>ACOC_CUCMA (P49608) Aconitate hydratase, cytoplasmic (EC 4.2.1.3) (Citrate|
           hydro-lyase) (Aconitase)
          Length = 898

 Score = 98.2 bits (243), Expect = 4e-21
 Identities = 44/58 (75%), Positives = 52/58 (89%)
 Frame = +3

Query: 234 EHAYSNILTSLPKPGGGEYGKFYSLPALNDPRIDKLPYSIRILLESAIRNCDGFQLPR 407
           E+ +   LTSLPKPGGGE+GK+YSLP+LNDPRID+LPYSIRILLESAIRNCD FQ+ +
Sbjct: 4   ENPFKENLTSLPKPGGGEFGKYYSLPSLNDPRIDRLPYSIRILLESAIRNCDNFQVKK 61

>ACOC_ARATH (Q42560) Aconitate hydratase, cytoplasmic (EC 4.2.1.3) (Citrate|
           hydro-lyase) (Aconitase)
          Length = 898

 Score = 91.3 bits (225), Expect = 5e-19
 Identities = 42/57 (73%), Positives = 50/57 (87%)
 Frame = +3

Query: 231 TEHAYSNILTSLPKPGGGEYGKFYSLPALNDPRIDKLPYSIRILLESAIRNCDGFQL 401
           +E+ + +IL +L KP GGE+G +YSLPALNDPRIDKLPYSIRILLESAIRNCD FQ+
Sbjct: 3   SENPFRSILKALEKPDGGEFGNYYSLPALNDPRIDKLPYSIRILLESAIRNCDEFQV 59

>IREB2_RAT (Q62751) Iron-responsive element-binding protein 2 (IRE-BP 2) (Iron|
           regulatory protein 2) (IRP2)
          Length = 963

 Score = 52.8 bits (125), Expect = 2e-07
 Identities = 22/43 (51%), Positives = 31/43 (72%)
 Frame = +3

Query: 279 GGEYGKFYSLPALNDPRIDKLPYSIRILLESAIRNCDGFQLPR 407
           G    KF+++P L   + D LPYSIR+LLE+A+RNCDGF + +
Sbjct: 19  GSSQKKFFNVPKLGGTKYDILPYSIRVLLEAAVRNCDGFLMKK 61

>IREB2_MOUSE (Q811J3) Iron-responsive element-binding protein 2 (IRE-BP 2) (Iron|
           regulatory protein 2) (IRP2)
          Length = 963

 Score = 52.8 bits (125), Expect = 2e-07
 Identities = 22/43 (51%), Positives = 31/43 (72%)
 Frame = +3

Query: 279 GGEYGKFYSLPALNDPRIDKLPYSIRILLESAIRNCDGFQLPR 407
           G    KF+++P L   + D LPYSIR+LLE+A+RNCDGF + +
Sbjct: 19  GNSQKKFFNVPKLGGTKYDILPYSIRVLLEAAVRNCDGFLMKK 61

>IREB1_HUMAN (P21399) Iron-responsive element-binding protein 1 (IRE-BP 1) (Iron|
           regulatory protein 1) (IRP1) (Ferritin repressor
           protein) (Aconitate hydratase) (EC 4.2.1.3) (Citrate
           hydro-lyase) (Aconitase)
          Length = 889

 Score = 47.8 bits (112), Expect = 6e-06
 Identities = 21/34 (61%), Positives = 27/34 (79%)
 Frame = +3

Query: 294 KFYSLPALNDPRIDKLPYSIRILLESAIRNCDGF 395
           KF++L  L D R  +LP+SIR+LLE+AIRNCD F
Sbjct: 20  KFFNLNKLEDSRYGRLPFSIRVLLEAAIRNCDEF 53

>IREB1_RAT (Q63270) Iron-responsive element-binding protein 1 (IRE-BP 1) (Iron|
           regulatory protein 1) (IRP1) (Ferritin repressor
           protein) (Aconitate hydratase) (EC 4.2.1.3) (Citrate
           hydro-lyase) (Aconitase)
          Length = 889

 Score = 47.4 bits (111), Expect = 8e-06
 Identities = 20/34 (58%), Positives = 27/34 (79%)
 Frame = +3

Query: 294 KFYSLPALNDPRIDKLPYSIRILLESAIRNCDGF 395
           KF++L  L D R  +LP+SIR+LLE+A+RNCD F
Sbjct: 20  KFFNLNKLEDSRYGRLPFSIRVLLEAAVRNCDEF 53

>IREB1_CHICK (Q90875) Iron-responsive element binding protein (IRE-BP) (Iron|
           regulatory protein) (IRP) (Ferritin repressor protein)
           (Aconitate hydratase) (EC 4.2.1.3) (Citrate hydro-lyase)
           (Aconitase)
          Length = 889

 Score = 47.4 bits (111), Expect = 8e-06
 Identities = 21/34 (61%), Positives = 27/34 (79%)
 Frame = +3

Query: 294 KFYSLPALNDPRIDKLPYSIRILLESAIRNCDGF 395
           KF++L  L D R  +LP+SIR+LLE+AIRNCD F
Sbjct: 20  KFFNLSKLEDVRYARLPFSIRVLLEAAIRNCDEF 53

>IREB1_MOUSE (P28271) Iron-responsive element-binding protein 1 (IRE-BP 1) (Iron|
           regulatory protein 1) (IRP1) (Ferritin repressor
           protein) (Aconitate hydratase) (EC 4.2.1.3) (Citrate
           hydro-lyase) (Aconitase)
          Length = 889

 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 19/34 (55%), Positives = 27/34 (79%)
 Frame = +3

Query: 294 KFYSLPALNDPRIDKLPYSIRILLESAIRNCDGF 395
           +F++L  L D R  +LP+SIR+LLE+A+RNCD F
Sbjct: 20  RFFNLNKLEDSRYGRLPFSIRVLLEAAVRNCDEF 53

>ACOC_CAEEL (Q23500) Probable aconitate hydratase, cytoplasmic (EC 4.2.1.3)|
           (Citrate hydro-lyase) (Aconitase)
          Length = 887

 Score = 45.4 bits (106), Expect = 3e-05
 Identities = 22/54 (40%), Positives = 36/54 (66%)
 Frame = +3

Query: 240 AYSNILTSLPKPGGGEYGKFYSLPALNDPRIDKLPYSIRILLESAIRNCDGFQL 401
           A++N++ +L    G    K++ L  LND R ++LP SI+ LLE+A+R+CD F +
Sbjct: 2   AFNNLIRNLAI--GDNVYKYFDLNGLNDARYNELPISIKYLLEAAVRHCDEFHV 53

>IREB2_HUMAN (P48200) Iron-responsive element-binding protein 2 (IRE-BP 2) (Iron|
           regulatory protein 2) (IRP2)
          Length = 963

 Score = 44.3 bits (103), Expect = 7e-05
 Identities = 20/38 (52%), Positives = 28/38 (73%)
 Frame = +3

Query: 294 KFYSLPALNDPRIDKLPYSIRILLESAIRNCDGFQLPR 407
           KF+ +  L   + D LPYSIR+LLE+A+RNCDGF + +
Sbjct: 24  KFFDVSKLGT-KYDVLPYSIRVLLEAAVRNCDGFLMKK 60

>IREB1_RABIT (Q01059) Iron-responsive element-binding protein 1 (IRE-BP 1) (Iron|
           regulatory protein 1) (IRP1) (Ferritin repressor
           protein) (Aconitate hydratase) (EC 4.2.1.3) (Citrate
           hydro-lyase) (Aconitase)
          Length = 889

 Score = 44.3 bits (103), Expect = 7e-05
 Identities = 19/34 (55%), Positives = 27/34 (79%)
 Frame = +3

Query: 294 KFYSLPALNDPRIDKLPYSIRILLESAIRNCDGF 395
           KF++L  L+  R  +LP+SIR+LLE+A+RNCD F
Sbjct: 20  KFFNLNKLDYSRYGRLPFSIRVLLEAAVRNCDKF 53

>ACON_BACSU (P09339) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)|
           (Aconitase)
          Length = 908

 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 21/45 (46%), Positives = 30/45 (66%), Gaps = 3/45 (6%)
 Frame = +3

Query: 282 GEYGKFYSLPALNDP---RIDKLPYSIRILLESAIRNCDGFQLPR 407
           G+   +YSL AL D    ++ KLPYSI++LLES +R  DGF + +
Sbjct: 22  GKTYHYYSLKALEDSGIGKVSKLPYSIKVLLESVLRQVDGFVIKK 66

>ACON_FRATH (Q2A1K3) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)|
           (Aconitase)
          Length = 937

 Score = 37.7 bits (86), Expect = 0.007
 Identities = 20/52 (38%), Positives = 31/52 (59%), Gaps = 3/52 (5%)
 Frame = +3

Query: 255 LTSLPKPGGGEYGKFYSLPALNDPR---IDKLPYSIRILLESAIRNCDGFQL 401
           +T L     G+    YSL  L+      + +LPYSIR+LLE+ +RN DG+++
Sbjct: 7   ITKLQIEDKGKKYSLYSLKKLSQELGKDVTRLPYSIRVLLENQLRNIDGYKV 58

>ACON_STAES (Q8CPC2) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)|
           (Aconitase)
          Length = 901

 Score = 36.2 bits (82), Expect = 0.019
 Identities = 19/41 (46%), Positives = 25/41 (60%), Gaps = 3/41 (7%)
 Frame = +3

Query: 282 GEYGKFYSLPALNDP---RIDKLPYSIRILLESAIRNCDGF 395
           G+   +Y L  L +    +I KLPYSIR+LLES +R  D F
Sbjct: 17  GQSYTYYDLQTLEEKGLAKISKLPYSIRVLLESVLRQEDDF 57

>ACON_STAEQ (Q5HPJ0) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)|
           (Aconitase)
          Length = 901

 Score = 36.2 bits (82), Expect = 0.019
 Identities = 19/41 (46%), Positives = 25/41 (60%), Gaps = 3/41 (7%)
 Frame = +3

Query: 282 GEYGKFYSLPALNDP---RIDKLPYSIRILLESAIRNCDGF 395
           G+   +Y L  L +    +I KLPYSIR+LLES +R  D F
Sbjct: 17  GQSYTYYDLQTLEEKGLAKISKLPYSIRVLLESVLRQEDDF 57

>ACON_STAAR (Q6GH55) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)|
           (Aconitase)
          Length = 901

 Score = 35.8 bits (81), Expect = 0.025
 Identities = 18/41 (43%), Positives = 26/41 (63%), Gaps = 3/41 (7%)
 Frame = +3

Query: 282 GEYGKFYSLPALNDP---RIDKLPYSIRILLESAIRNCDGF 395
           G+   +Y L A+ +    ++ KLPYSIR+LLES +R  D F
Sbjct: 17  GQSYTYYDLKAVEEQGITKVSKLPYSIRVLLESLLRQEDDF 57

>ACON_BRAJA (P70920) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)|
           (Aconitase)
          Length = 906

 Score = 34.3 bits (77), Expect = 0.072
 Identities = 17/35 (48%), Positives = 23/35 (65%), Gaps = 3/35 (8%)
 Frame = +3

Query: 297 FYSLPALND---PRIDKLPYSIRILLESAIRNCDG 392
           +YSLP         I KLPYS+++LLE+ +RN DG
Sbjct: 22  YYSLPTAEKNGLKGISKLPYSMKVLLENLLRNEDG 56

>ACON_STAAW (P63434) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)|
           (Aconitase)
          Length = 901

 Score = 34.3 bits (77), Expect = 0.072
 Identities = 19/41 (46%), Positives = 25/41 (60%), Gaps = 3/41 (7%)
 Frame = +3

Query: 282 GEYGKFYSLPALNDPRIDK---LPYSIRILLESAIRNCDGF 395
           G+   +Y L A+ +  I K   LPYSIR+LLES +R  D F
Sbjct: 17  GQSYTYYDLKAVEEQGITKVSNLPYSIRVLLESLLRQEDDF 57

>ACON_STAAS (Q6G9K9) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)|
           (Aconitase)
          Length = 901

 Score = 34.3 bits (77), Expect = 0.072
 Identities = 19/41 (46%), Positives = 25/41 (60%), Gaps = 3/41 (7%)
 Frame = +3

Query: 282 GEYGKFYSLPALNDPRIDK---LPYSIRILLESAIRNCDGF 395
           G+   +Y L A+ +  I K   LPYSIR+LLES +R  D F
Sbjct: 17  GQSYTYYDLKAVEEQGITKVSNLPYSIRVLLESLLRQEDDF 57

>ACON_STAAN (P99148) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)|
           (Aconitase)
          Length = 901

 Score = 34.3 bits (77), Expect = 0.072
 Identities = 19/41 (46%), Positives = 25/41 (60%), Gaps = 3/41 (7%)
 Frame = +3

Query: 282 GEYGKFYSLPALNDPRIDK---LPYSIRILLESAIRNCDGF 395
           G+   +Y L A+ +  I K   LPYSIR+LLES +R  D F
Sbjct: 17  GQSYTYYDLKAVEEQGITKVSNLPYSIRVLLESLLRQEDDF 57

>ACON_STAAM (P63433) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)|
           (Aconitase)
          Length = 901

 Score = 34.3 bits (77), Expect = 0.072
 Identities = 19/41 (46%), Positives = 25/41 (60%), Gaps = 3/41 (7%)
 Frame = +3

Query: 282 GEYGKFYSLPALNDPRIDK---LPYSIRILLESAIRNCDGF 395
           G+   +Y L A+ +  I K   LPYSIR+LLES +R  D F
Sbjct: 17  GQSYTYYDLKAVEEQGITKVSNLPYSIRVLLESLLRQEDDF 57

>ACON_STAAC (Q5HG69) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)|
           (Aconitase)
          Length = 901

 Score = 34.3 bits (77), Expect = 0.072
 Identities = 19/41 (46%), Positives = 25/41 (60%), Gaps = 3/41 (7%)
 Frame = +3

Query: 282 GEYGKFYSLPALNDPRIDK---LPYSIRILLESAIRNCDGF 395
           G+   +Y L A+ +  I K   LPYSIR+LLES +R  D F
Sbjct: 17  GQSYTYYDLKAVEEQGITKVSNLPYSIRVLLESLLRQEDDF 57

>ACON_MYCAV (O08451) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)|
           (Aconitase)
          Length = 961

 Score = 33.5 bits (75), Expect = 0.12
 Identities = 16/43 (37%), Positives = 27/43 (62%)
 Frame = +3

Query: 279 GGEYGKFYSLPALNDPRIDKLPYSIRILLESAIRNCDGFQLPR 407
           G +  + Y L A+  P  +KLPYS+++L E+ +RN DG  + +
Sbjct: 44  GDKSYQIYRLDAV--PNTEKLPYSLKVLAENLLRNEDGSNITK 84

>ACON_CORJK (Q4JVM4) Aconitate hydratase (EC 4.2.1.3)|
          Length = 936

 Score = 32.7 bits (73), Expect = 0.21
 Identities = 15/37 (40%), Positives = 27/37 (72%)
 Frame = +3

Query: 297 FYSLPALNDPRIDKLPYSIRILLESAIRNCDGFQLPR 407
           +++L A+  P ++KLPYS+++L E+ +RN DG  + R
Sbjct: 23  YFALDAV--PGMEKLPYSLKVLGENLLRNEDGKNITR 57

>ACON_COREF (Q8FTA8) Aconitate hydratase (EC 4.2.1.3)|
          Length = 937

 Score = 30.8 bits (68), Expect = 0.80
 Identities = 14/32 (43%), Positives = 24/32 (75%)
 Frame = +3

Query: 297 FYSLPALNDPRIDKLPYSIRILLESAIRNCDG 392
           +Y+L A+  P ++KLPYS+++L E+ +R  DG
Sbjct: 23  YYALSAV--PGMEKLPYSLKVLGENLLRTEDG 52

>UBP30_HUMAN (Q70CQ3) Ubiquitin carboxyl-terminal hydrolase 30 (EC 3.1.2.15)|
           (Ubiquitin thioesterase 30)
           (Ubiquitin-specific-processing protease 30)
           (Deubiquitinating enzyme 30)
          Length = 517

 Score = 30.0 bits (66), Expect = 1.4
 Identities = 13/26 (50%), Positives = 20/26 (76%)
 Frame = +1

Query: 268 LSPGVVNMGNSTAFLH*MIQGSISCP 345
           L PG+VN+GN T F++ ++QG  +CP
Sbjct: 66  LVPGLVNLGN-TCFMNSLLQGLSACP 90

>ACON_STRMU (Q59938) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)|
           (Aconitase)
          Length = 888

 Score = 30.0 bits (66), Expect = 1.4
 Identities = 13/23 (56%), Positives = 17/23 (73%)
 Frame = +3

Query: 321 DPRIDKLPYSIRILLESAIRNCD 389
           D  +D LPY+I+ILLES +R  D
Sbjct: 28  DIELDSLPYTIKILLESLLRKHD 50

>ACON_CORGL (Q8NQ98) Aconitate hydratase (EC 4.2.1.3)|
          Length = 939

 Score = 29.3 bits (64), Expect = 2.3
 Identities = 13/32 (40%), Positives = 24/32 (75%)
 Frame = +3

Query: 297 FYSLPALNDPRIDKLPYSIRILLESAIRNCDG 392
           +++L A+  P ++KLPYS+++L E+ +R  DG
Sbjct: 23  YFALSAV--PGMEKLPYSLKVLGENLLRTEDG 52

>ACON_LEGPH (P37032) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)|
           (Aconitase) (Major iron-containing protein) (MICP)
           (IP210)
          Length = 891

 Score = 29.3 bits (64), Expect = 2.3
 Identities = 15/40 (37%), Positives = 25/40 (62%), Gaps = 3/40 (7%)
 Frame = +3

Query: 282 GEYGKFYSLPALNDPR---IDKLPYSIRILLESAIRNCDG 392
           G+   +YSL    +     I++LPYS+++LLE+ +R  DG
Sbjct: 18  GKTYNYYSLKEAENKHFKGINRLPYSLKVLLENLLRFEDG 57

>HYIN1_BRAJA (P59385) Indoleacetamide hydrolase (EC 3.5.1.-) (IAH)|
           (Indole-3-acetamide hydrolase)
          Length = 524

 Score = 28.9 bits (63), Expect = 3.0
 Identities = 12/32 (37%), Positives = 17/32 (53%)
 Frame = -2

Query: 342 AAYRSLDHLVQEGCRISHIHHPRA*GGWSKYC 247
           A  R+ DHL + G R+S +  P   G W  +C
Sbjct: 334 ALRRAADHLERSGYRVSEVEVPDINGVWQTWC 365

>PHD1_YEAST (P36093) Putative transcription factor PHD1|
          Length = 366

 Score = 27.3 bits (59), Expect = 8.8
 Identities = 16/54 (29%), Positives = 28/54 (51%), Gaps = 3/54 (5%)
 Frame = +3

Query: 231 TEHAYSNIL---TSLPKPGGGEYGKFYSLPALNDPRIDKLPYSIRILLESAIRN 383
           T +AY+N+    TS  +   G Y ++Y++P    P+  + PY   +L  + I N
Sbjct: 53  TPNAYANVAQLATSPTQAKSGYYCRYYAVPFPTYPQQPQSPYQQAVLPYATIPN 106

>ACON_RICPR (Q9ZCF4) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)|
           (Aconitase)
          Length = 878

 Score = 27.3 bits (59), Expect = 8.8
 Identities = 10/17 (58%), Positives = 15/17 (88%)
 Frame = +3

Query: 330 IDKLPYSIRILLESAIR 380
           + KLPYS+R+LLE+ +R
Sbjct: 36  LKKLPYSLRVLLENVLR 52


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 37,650,303
Number of Sequences: 219361
Number of extensions: 649390
Number of successful extensions: 1335
Number of sequences better than 10.0: 32
Number of HSP's better than 10.0 without gapping: 1313
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 1335
length of database: 80,573,946
effective HSP length: 112
effective length of database: 56,005,514
effective search space used: 1344132336
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)