>VILI1_ARATH (O81643) Villin-1|
Length = 910
Score = 145 bits (365), Expect = 5e-35
Identities = 69/127 (54%), Positives = 95/127 (74%), Gaps = 1/127 (0%)
Frame = +3
Query: 39 YDVHFWIGKDSSQDEAGTAAIKTVELDSVLGGRAVQYRELQGYESDKFLSYFKPCIIPME 218
YD+H+W+G D+++ ++ A+ K ++LD+ LG VQYRE+QG E++KFLSYFKPCIIP+E
Sbjct: 63 YDIHYWLGIDANEVDSILASDKALDLDAALGCCTVQYREVQGQETEKFLSYFKPCIIPVE 122
Query: 219 GGFASGFKTP-EEETFETRLYICKGKRAIRIKQVPFARSSLNHDDVFILDTEKKIYQFNG 395
G ++ KT ET++ L CKG +R+K+VPF RSSLNHDDVFILDT K++ F G
Sbjct: 123 GKYSP--KTGIAGETYQVTLLRCKGDHVVRVKEVPFLRSSLNHDDVFILDTASKVFLFAG 180
Query: 396 CNSNIQE 416
CNS+ QE
Sbjct: 181 CNSSTQE 187
Score = 37.7 bits (86), Expect = 0.011
Identities = 33/124 (26%), Positives = 57/124 (45%), Gaps = 4/124 (3%)
Frame = +3
Query: 54 WIGKDSSQDEAGTAAIKTVELDSVLGGRAVQYRELQGYESDKFLSYFKPCIIPMEGGFAS 233
WIGK SS + LD+ ++ +G E+D F + GG +
Sbjct: 559 WIGKLSSDSDHEVLDRMLYFLDTSCQPTYIR----EGNETDTFWNLL--------GGKSE 606
Query: 234 GFKTPE--EETFETRLYICK-GKRAIRIKQV-PFARSSLNHDDVFILDTEKKIYQFNGCN 401
K E ++ E L+ C +++K++ F + L +DVF+LD + ++Y + G N
Sbjct: 607 YPKEKEMRKQIEEPHLFTCSCSSDVLKVKEIYNFVQDDLTTEDVFLLDCQSEVYVWIGSN 666
Query: 402 SNIQ 413
SNI+
Sbjct: 667 SNIK 670
>GELS_CHICK (O93510) Gelsolin precursor (Actin-depolymerizing factor) (ADF)|
(Brevin) (Homogenin)
Length = 778
Score = 129 bits (323), Expect = 4e-30
Identities = 71/140 (50%), Positives = 88/140 (62%), Gaps = 2/140 (1%)
Frame = +3
Query: 3 LQTTSPKGGAYLYDVHFWIGKDSSQDEAGTAAIKTVELDSVLGGRAVQYRELQGYESDKF 182
L T + G YD+HFW+G +SSQDE G AAI TV++D L G+AVQ+RE+QG+ES F
Sbjct: 94 LNTIRQRSGNLQYDLHFWLGDESSQDERGAAAIFTVQMDDYLQGKAVQHREVQGHESSTF 153
Query: 183 LSYFKPCIIPMEGGFASGFK--TPEEETFETRLYICKGKRAIRIKQVPFARSSLNHDDVF 356
L YFK I GG ASGF+ P E T + RL KG+R +R +VP + S N D F
Sbjct: 154 LGYFKSGIKYKAGGVASGFRHVVPNEVTVQ-RLLQVKGRRTVRATEVPVSWESFNTGDCF 212
Query: 357 ILDTEKKIYQFNGCNSNIQE 416
ILD IYQ+ G NSN QE
Sbjct: 213 ILDLGSNIYQWCGSNSNRQE 232
Score = 68.6 bits (166), Expect = 6e-12
Identities = 47/128 (36%), Positives = 63/128 (49%), Gaps = 4/128 (3%)
Frame = +3
Query: 45 VHFWIGKDSSQDEAGTAAIKTVELDSVLGGRAVQYRELQGYESDKFLSYF--KPCIIPME 218
++ W G S+QDE T+A TV+LD LGG VQ R +QG E +S F KP I+
Sbjct: 486 IYTWQGAHSTQDEIATSAFLTVQLDEELGGSPVQKRVVQGKEPPHLMSMFGGKPLIVYKG 545
Query: 219 GGFASGFKTPEEET--FETRLYICKGKRAIRIKQVPFARSSLNHDDVFILDTEKKIYQFN 392
G G +T +T F+ R RA+ + A S LN +D F+L T Y +
Sbjct: 546 GTSREGGQTTPAQTRLFQVRSSTSGATRAVELDP---AASQLNSNDAFVLKTPSAAYLWV 602
Query: 393 GCNSNIQE 416
G SN E
Sbjct: 603 GRGSNSAE 610
Score = 40.4 bits (93), Expect = 0.002
Identities = 35/133 (26%), Positives = 64/133 (48%), Gaps = 8/133 (6%)
Frame = +3
Query: 42 DVHFWIGKDSSQDEAGTAAIKTVEL-DSVLGGRAVQYRELQGYESDKFLSYFKPCIIPME 218
+++ W G +S++ E A + + D+ GRA + +G E ++ L P +
Sbjct: 219 NIYQWCGSNSNRQERLKATVLAKGIRDNEKNGRAKVFVSEEGAEREEMLQVLGPKP-SLP 277
Query: 219 GGFASGFKTPEEETFETRLY-ICKGKRAIRIKQV----PFARSSLNHDDVFILD--TEKK 377
G + KT +LY + G + + V PF++++LN +D FILD T+ K
Sbjct: 278 QGASDDTKTDTANRKLAKLYKVSNGAGNMAVSLVADENPFSQAALNTEDCFILDHGTDGK 337
Query: 378 IYQFNGCNSNIQE 416
I+ + G ++N E
Sbjct: 338 IFVWKGRSANSDE 350
Score = 40.0 bits (92), Expect = 0.002
Identities = 39/131 (29%), Positives = 58/131 (44%), Gaps = 8/131 (6%)
Frame = +3
Query: 48 HFWIGKDSSQDEAGTAAIKTVELDSVLGGRAVQYRELQGYESDKFLSYFKPCIIPMEGGF 227
+ W+G+ S+ E A EL VLG R VQ E G E D F GG
Sbjct: 599 YLWVGRGSNSAELSGAQ----ELLKVLGARPVQVSE--GREPDNFWVAL--------GGK 644
Query: 228 ASGFKTP-----EEETFETRLYICKGKRA-IRIKQVP--FARSSLNHDDVFILDTEKKIY 383
A +P + + + RL+ C K I++VP + L DDV ILDT +++
Sbjct: 645 APYRTSPRLKDKKMDAYPPRLFACSNKSGRFTIEEVPGDLTQDDLATDDVMILDTWDQVF 704
Query: 384 QFNGCNSNIQE 416
+ G ++ +E
Sbjct: 705 VWIGKDAQEEE 715
>GELS_PIG (P20305) Gelsolin precursor (Actin-depolymerizing factor) (ADF)|
(Brevin) (Fragment)
Length = 772
Score = 128 bits (322), Expect = 5e-30
Identities = 69/140 (49%), Positives = 89/140 (63%), Gaps = 2/140 (1%)
Frame = +3
Query: 3 LQTTSPKGGAYLYDVHFWIGKDSSQDEAGTAAIKTVELDSVLGGRAVQYRELQGYESDKF 182
L+T + G YD+H+W+G + SQDE+G AAI TV+LD L GRAVQ+RE+QG+ES F
Sbjct: 88 LKTVQLRNGNLQYDLHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATF 147
Query: 183 LSYFKPCIIPMEGGFASGFK--TPEEETFETRLYICKGKRAIRIKQVPFARSSLNHDDVF 356
L YFK + +GG ASGFK P E + RL+ KG+R +R +VP + S N D F
Sbjct: 148 LGYFKSGLKYKKGGVASGFKHVVPNEVAVQ-RLFQVKGRRVVRATEVPVSWESFNRGDCF 206
Query: 357 ILDTEKKIYQFNGCNSNIQE 416
ILD IYQ+ G NSN E
Sbjct: 207 ILDLGNDIYQWCGSNSNRYE 226
Score = 63.2 bits (152), Expect = 2e-10
Identities = 47/135 (34%), Positives = 65/135 (48%), Gaps = 4/135 (2%)
Frame = +3
Query: 24 GGAYLYDVHFWIGKDSSQDEAGTAAIKTVELDSVLGGRAVQYRELQGYESDKFLSYF--K 197
GG ++ W G S+QDE +AI T +LD LGG VQ R +QG E +S F K
Sbjct: 473 GGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEPAHLMSLFGGK 532
Query: 198 PCIIPMEGGFASGFKTPEEET--FETRLYICKGKRAIRIKQVPFARSSLNHDDVFILDTE 371
P II G G +T T F+ R RA+ + +P A +LN +D F+L T
Sbjct: 533 PMIIYRGGTSREGGQTAPASTRLFQVRASSSGATRAVEV--IPKA-GALNSNDAFVLKTP 589
Query: 372 KKIYQFNGCNSNIQE 416
Y + G ++ E
Sbjct: 590 SAAYLWVGTGASEAE 604
Score = 32.0 bits (71), Expect = 0.59
Identities = 36/131 (27%), Positives = 57/131 (43%), Gaps = 8/131 (6%)
Frame = +3
Query: 48 HFWIGKDSSQDEAGTAAIKTVELDSVLGGRAVQYRELQGYESDKFLSYFKPCIIPMEGGF 227
+ W+G +S+ E A EL VL + VQ E G E D F GG
Sbjct: 593 YLWVGTGASEAEKTGAQ----ELLRVLRAQPVQVAE--GSEPDSFWEAL--------GGK 638
Query: 228 ASGFKTP-----EEETFETRLYICKGKRA-IRIKQVP--FARSSLNHDDVFILDTEKKIY 383
A+ +P + + RL+ C K +++VP + L DDV +LDT +++
Sbjct: 639 AAYRTSPRLKDKKMDAHPPRLFACSNKIGRFVVEEVPGELMQEDLATDDVMLLDTWDQVF 698
Query: 384 QFNGCNSNIQE 416
+ G +S +E
Sbjct: 699 VWVGKDSQEEE 709
Score = 30.4 bits (67), Expect = 1.7
Identities = 33/133 (24%), Positives = 54/133 (40%), Gaps = 8/133 (6%)
Frame = +3
Query: 42 DVHFWIGKDSSQDEA--GTAAIKTVELDSVLGGRAVQYRELQGYESDKFLSYFKPCIIPM 215
D++ W G +S++ E T K + D+ GRA + + E L P
Sbjct: 213 DIYQWCGSNSNRYERLKATQVSKGIR-DNERSGRAHVHVSEEDAEPAGMLQVLGPKPTLP 271
Query: 216 EGGFASGFKTPEEETFETRLYICKGKRAIRIKQV----PFARSSLNHDDVFILDTEK--K 377
EG + + + G + + V PFA+ +L +D FILD K K
Sbjct: 272 EGTEDTVKEDAANRKLAKLYKVSNGAGTMTVSLVADENPFAQGALKSEDCFILDHGKDGK 331
Query: 378 IYQFNGCNSNIQE 416
I+ + G +N +E
Sbjct: 332 IFVWKGKQANTEE 344
Score = 30.0 bits (66), Expect = 2.3
Identities = 18/54 (33%), Positives = 28/54 (51%), Gaps = 4/54 (7%)
Frame = +3
Query: 45 VHFWIGKDSSQD---EAGTAAIKTVELDSVLGGRAVQYREL-QGYESDKFLSYF 194
V W+GKDS ++ EA T+A + +E D R + QG+E F+ +F
Sbjct: 697 VFVWVGKDSQEEEKTEALTSAKRYIETDPANRDRRTPINVVKQGFEPPSFVGWF 750
>GELS_HUMAN (P06396) Gelsolin precursor (Actin-depolymerizing factor) (ADF)|
(Brevin) (AGEL)
Length = 782
Score = 127 bits (319), Expect = 1e-29
Identities = 67/139 (48%), Positives = 88/139 (63%), Gaps = 1/139 (0%)
Frame = +3
Query: 3 LQTTSPKGGAYLYDVHFWIGKDSSQDEAGTAAIKTVELDSVLGGRAVQYRELQGYESDKF 182
L+T + G YD+H+W+G + SQDE+G AAI TV+LD L GRAVQ+RE+QG+ES F
Sbjct: 98 LKTVQLRNGNLQYDLHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATF 157
Query: 183 LSYFKPCIIPMEGGFASGFK-TPEEETFETRLYICKGKRAIRIKQVPFARSSLNHDDVFI 359
L YFK + +GG ASGFK E RL+ KG+R +R +VP + S N+ D FI
Sbjct: 158 LGYFKSGLKYKKGGVASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFI 217
Query: 360 LDTEKKIYQFNGCNSNIQE 416
LD I+Q+ G NSN E
Sbjct: 218 LDLGNNIHQWCGSNSNRYE 236
Score = 62.8 bits (151), Expect = 3e-10
Identities = 47/135 (34%), Positives = 65/135 (48%), Gaps = 4/135 (2%)
Frame = +3
Query: 24 GGAYLYDVHFWIGKDSSQDEAGTAAIKTVELDSVLGGRAVQYRELQGYESDKFLSYF--K 197
GG ++ W G S+QDE +AI T +LD LGG VQ R +QG E +S F K
Sbjct: 483 GGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEPAHLMSLFGGK 542
Query: 198 PCIIPMEGGFASGFKTPEEET--FETRLYICKGKRAIRIKQVPFARSSLNHDDVFILDTE 371
P II G G +T T F+ R RA+ + +P A +LN +D F+L T
Sbjct: 543 PMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEV--LPKA-GALNSNDAFVLKTP 599
Query: 372 KKIYQFNGCNSNIQE 416
Y + G ++ E
Sbjct: 600 SAAYLWVGTGASEAE 614
Score = 35.0 bits (79), Expect = 0.070
Identities = 36/134 (26%), Positives = 58/134 (43%), Gaps = 9/134 (6%)
Frame = +3
Query: 42 DVHFWIGKDSSQDEA--GTAAIKTVELDSVLGGRAVQYRELQGYESDKFLSYFKPCIIPM 215
++H W G +S++ E T K + D+ GRA + +G E + L P +
Sbjct: 223 NIHQWCGSNSNRYERLKATQVSKGIR-DNERSGRARVHVSEEGTEPEAMLQVLGPKPA-L 280
Query: 216 EGGFASGFKTPEEETFETRLY-ICKGKRAIRIKQV----PFARSSLNHDDVFILDTEK-- 374
G K +LY + G + + V PFA+ +L +D FILD K
Sbjct: 281 PAGTEDTAKEDAANRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDG 340
Query: 375 KIYQFNGCNSNIQE 416
KI+ + G +N +E
Sbjct: 341 KIFVWKGKQANTEE 354
Score = 31.6 bits (70), Expect = 0.78
Identities = 37/131 (28%), Positives = 57/131 (43%), Gaps = 8/131 (6%)
Frame = +3
Query: 48 HFWIGKDSSQDEAGTAAIKTVELDSVLGGRAVQYRELQGYESDKFLSYFKPCIIPMEGGF 227
+ W+G +S+ E A EL VL + VQ E G E D F GG
Sbjct: 603 YLWVGTGASEAEKTGAQ----ELLRVLRAQPVQVAE--GSEPDGFWEAL--------GGK 648
Query: 228 ASGFKTP-----EEETFETRLYICKGKRA-IRIKQVP--FARSSLNHDDVFILDTEKKIY 383
A+ +P + + RL+ C K I++VP + L DDV +LDT +++
Sbjct: 649 AAYRTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVF 708
Query: 384 QFNGCNSNIQE 416
+ G +S +E
Sbjct: 709 VWVGKDSQEEE 719
Score = 29.6 bits (65), Expect = 2.9
Identities = 18/54 (33%), Positives = 28/54 (51%), Gaps = 4/54 (7%)
Frame = +3
Query: 45 VHFWIGKDSSQD---EAGTAAIKTVELDSVLGGRAVQYREL-QGYESDKFLSYF 194
V W+GKDS ++ EA T+A + +E D R + QG+E F+ +F
Sbjct: 707 VFVWVGKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWF 760
>GELS_HORSE (Q28372) Gelsolin (Actin-depolymerizing factor) (ADF) (Brevin)|
Length = 730
Score = 125 bits (314), Expect = 4e-29
Identities = 66/136 (48%), Positives = 85/136 (62%), Gaps = 1/136 (0%)
Frame = +3
Query: 3 LQTTSPKGGAYLYDVHFWIGKDSSQDEAGTAAIKTVELDSVLGGRAVQYRELQGYESDKF 182
L+T + G YD+H+W+G + SQDE+G AAI TV+LD L GRAVQ+RE+QG+ES F
Sbjct: 46 LKTVQLRNGILQYDLHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATF 105
Query: 183 LSYFKPCIIPMEGGFASGFK-TPEEETFETRLYICKGKRAIRIKQVPFARSSLNHDDVFI 359
L YFK + +GG ASGFK E RL KG+R +R +VP + S N+ D FI
Sbjct: 106 LGYFKSGLKYKKGGVASGFKHVVPNEVVVQRLLQVKGRRVVRATEVPVSWESFNNGDCFI 165
Query: 360 LDTEKKIYQFNGCNSN 407
LD IYQ+ G SN
Sbjct: 166 LDLGNNIYQWCGSKSN 181
Score = 62.8 bits (151), Expect = 3e-10
Identities = 45/128 (35%), Positives = 63/128 (49%), Gaps = 4/128 (3%)
Frame = +3
Query: 45 VHFWIGKDSSQDEAGTAAIKTVELDSVLGGRAVQYRELQGYESDKFLSYF--KPCIIPME 218
++ W G S+QDE +AI T +LD LGG VQ R +QG E +S F KP I+
Sbjct: 438 IYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIVYKG 497
Query: 219 GGFASGFKTPEEET--FETRLYICKGKRAIRIKQVPFARSSLNHDDVFILDTEKKIYQFN 392
G G +T T F+ R RA+ I +P A +LN +D F+L T Y +
Sbjct: 498 GTSREGGQTAPASTRLFQVRASSSGATRAVEI--IPKA-GALNSNDAFVLKTPSAAYLWV 554
Query: 393 GCNSNIQE 416
G ++ E
Sbjct: 555 GAGASEAE 562
Score = 34.7 bits (78), Expect = 0.092
Identities = 38/131 (29%), Positives = 58/131 (44%), Gaps = 8/131 (6%)
Frame = +3
Query: 48 HFWIGKDSSQDEAGTAAIKTVELDSVLGGRAVQYRELQGYESDKFLSYFKPCIIPMEGGF 227
+ W+G +S+ E A EL VL + VQ E G E D F GG
Sbjct: 551 YLWVGAGASEAEKTGAQ----ELLRVLRAQPVQVAE--GSEPDSFWEAL--------GGK 596
Query: 228 ASGFKTP-----EEETFETRLYICKGKRA-IRIKQVP--FARSSLNHDDVFILDTEKKIY 383
A+ +P + + RL+ C K I++VP F + L DDV +LDT +++
Sbjct: 597 ATYRTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGEFMQEDLATDDVMLLDTWDQVF 656
Query: 384 QFNGCNSNIQE 416
+ G +S +E
Sbjct: 657 VWVGKDSQDEE 667
Score = 30.0 bits (66), Expect = 2.3
Identities = 15/35 (42%), Positives = 23/35 (65%), Gaps = 2/35 (5%)
Frame = +3
Query: 318 PFARSSLNHDDVFILDTEK--KIYQFNGCNSNIQE 416
PFA+ +L +D FILD K KI+ + G +N++E
Sbjct: 268 PFAQGALRSEDCFILDHGKDGKIFVWKGKQANMEE 302
>GELS_MOUSE (P13020) Gelsolin precursor (Actin-depolymerizing factor) (ADF)|
(Brevin)
Length = 780
Score = 125 bits (313), Expect = 5e-29
Identities = 65/136 (47%), Positives = 85/136 (62%), Gaps = 1/136 (0%)
Frame = +3
Query: 3 LQTTSPKGGAYLYDVHFWIGKDSSQDEAGTAAIKTVELDSVLGGRAVQYRELQGYESDKF 182
L+T + G YD+H+W+G + SQDE+G AAI TV+LD L GRAVQ+RE+QG+ES F
Sbjct: 96 LKTVQLRNGNLQYDLHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESSTF 155
Query: 183 LSYFKPCIIPMEGGFASGFK-TPEEETFETRLYICKGKRAIRIKQVPFARSSLNHDDVFI 359
YFK + +GG ASGFK E RL+ KG+R +R +VP + S N+ D FI
Sbjct: 156 SGYFKSGLKYKKGGVASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWDSFNNGDCFI 215
Query: 360 LDTEKKIYQFNGCNSN 407
LD IYQ+ G SN
Sbjct: 216 LDLGNNIYQWCGSGSN 231
Score = 59.7 bits (143), Expect = 3e-09
Identities = 44/135 (32%), Positives = 61/135 (45%), Gaps = 4/135 (2%)
Frame = +3
Query: 24 GGAYLYDVHFWIGKDSSQDEAGTAAIKTVELDSVLGGRAVQYRELQGYESDKFLSYF--K 197
GG ++ W G S+QDE +AI T +LD LGG VQ R +QG E +S F K
Sbjct: 481 GGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEPAHLMSLFGGK 540
Query: 198 PCIIPMEGGFASGFKTPEE--ETFETRLYICKGKRAIRIKQVPFARSSLNHDDVFILDTE 371
P II G G +T F+ R RA+ + +LN +D F+L T
Sbjct: 541 PMIIYKGGTSRDGGQTAPASIRLFQVRASSSGATRAVEVMP---KSGALNSNDAFVLKTP 597
Query: 372 KKIYQFNGCNSNIQE 416
Y + G ++ E
Sbjct: 598 SAAYLWVGAGASEAE 612
Score = 33.9 bits (76), Expect = 0.16
Identities = 32/133 (24%), Positives = 57/133 (42%), Gaps = 8/133 (6%)
Frame = +3
Query: 42 DVHFWIGKDSSQDEA--GTAAIKTVELDSVLGGRAVQYRELQGYESDKFLSYFKPCIIPM 215
+++ W G S++ E T K + D+ GRA + +G E + L P
Sbjct: 221 NIYQWCGSGSNKFERLKATQVSKGIR-DNERSGRAQVHVSEEGGEPEAMLQVLGPKPALP 279
Query: 216 EGGFASGFKTPEEETFETRLYICKGKRAIRIKQV----PFARSSLNHDDVFILD--TEKK 377
EG + + + G ++ + V PFA+ +L +D FILD + K
Sbjct: 280 EGTEDTAKEDAANRRLAKLYKVSNGAGSMSVSLVADENPFAQGALRSEDCFILDHGRDGK 339
Query: 378 IYQFNGCNSNIQE 416
I+ + G +N++E
Sbjct: 340 IFVWKGKQANMEE 352
Score = 29.6 bits (65), Expect = 2.9
Identities = 18/54 (33%), Positives = 28/54 (51%), Gaps = 4/54 (7%)
Frame = +3
Query: 45 VHFWIGKDSSQD---EAGTAAIKTVELDSVLGGRAVQYREL-QGYESDKFLSYF 194
V W+GKDS ++ EA T+A + +E D R + QG+E F+ +F
Sbjct: 705 VFVWVGKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVRQGFEPPSFVGWF 758
Score = 29.6 bits (65), Expect = 2.9
Identities = 35/131 (26%), Positives = 56/131 (42%), Gaps = 8/131 (6%)
Frame = +3
Query: 48 HFWIGKDSSQDEAGTAAIKTVELDSVLGGRAVQYRELQGYESDKFLSYFKPCIIPMEGGF 227
+ W+G +S+ E A EL VL + VQ E G E D F GG
Sbjct: 601 YLWVGAGASEAEKTGAQ----ELLKVLRSQHVQVEE--GSEPDAFWEAL--------GGK 646
Query: 228 ASGFKTP-----EEETFETRLYICKGKRA-IRIKQVP--FARSSLNHDDVFILDTEKKIY 383
+ +P + + RL+ C + I++VP + L DDV +LDT +++
Sbjct: 647 TAYRTSPRLKDKKMDAHPPRLFACSNRIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVF 706
Query: 384 QFNGCNSNIQE 416
+ G +S +E
Sbjct: 707 VWVGKDSQEEE 717
>AVIL_HUMAN (O75366) Advillin (p92)|
Length = 819
Score = 123 bits (308), Expect = 2e-28
Identities = 68/126 (53%), Positives = 80/126 (63%), Gaps = 1/126 (0%)
Frame = +3
Query: 42 DVHFWIGKDSSQDEAGTAAIKTVELDSVLGGRAVQYRELQGYESDKFLSYFKPCIIPMEG 221
D+HFWIGKDSSQDE AAI T +LD LGG VQ+RE+Q +ESD F YFK II +G
Sbjct: 58 DIHFWIGKDSSQDEQSCAAIYTTQLDDYLGGSPVQHREVQYHESDTFRGYFKQGIIYKQG 117
Query: 222 GFASGFKTPEEETFET-RLYICKGKRAIRIKQVPFARSSLNHDDVFILDTEKKIYQFNGC 398
G ASG K E T++ RL KGKR IR +V + S N DVF+LD K I Q+NG
Sbjct: 118 GVASGMKHVETNTYDVKRLLHVKGKRNIRATEVEMSWDSFNRGDVFLLDLGKVIIQWNGP 177
Query: 399 NSNIQE 416
SN E
Sbjct: 178 ESNSGE 183
Score = 62.4 bits (150), Expect = 4e-10
Identities = 43/126 (34%), Positives = 64/126 (50%), Gaps = 2/126 (1%)
Frame = +3
Query: 45 VHFWIGKDSSQDEAGTAAIKTVELDSVLGGRAVQYRELQGYESDKFLSYFKPCIIPMEGG 224
++ W + +SQDE +A + VE+D G AVQ R G E F++ FK ++ EGG
Sbjct: 440 LYIWQDRHASQDELAASAYQAVEVDRQFDGAAVQVRVRMGTEPRHFMAIFKGKLVIFEGG 499
Query: 225 FASGFKTPEEETFETRLYICKG--KRAIRIKQVPFARSSLNHDDVFILDTEKKIYQFNGC 398
+ K E RL+ G K + +VP SSLN +DVF+L T+ + Y + G
Sbjct: 500 --TSRKGNAEPDPPVRLFQIHGNDKSNTKAVEVPAFASSLNSNDVFLLRTQAEHYLWYGK 557
Query: 399 NSNIQE 416
S+ E
Sbjct: 558 GSSGDE 563
>GELS_HOMAM (Q27319) Gelsolin, cytoplasmic (Actin-depolymerizing factor) (ADF)|
Length = 754
Score = 120 bits (301), Expect = 1e-27
Identities = 63/132 (47%), Positives = 87/132 (65%), Gaps = 1/132 (0%)
Frame = +3
Query: 12 TSPKGGAYLYDVHFWIGKDSSQDEAGTAAIKTVELDSVLGGRAVQYRELQGYESDKFLSY 191
T G +D+HFW+G ++SQDEAGTAAIKTVELD LGG VQ+RE++G+E+ FLS
Sbjct: 46 TRDVNGNLSWDLHFWLGSETSQDEAGTAAIKTVELDDQLGGVPVQHREVEGHETSLFLSR 105
Query: 192 FKPCIIPMEGGFASGFKTPEEET-FETRLYICKGKRAIRIKQVPFARSSLNHDDVFILDT 368
FK + ++GG ASGF + + + RL+ KG+R IRI+QV S+N D FILD
Sbjct: 106 FKKGVRYLKGGVASGFHHVDPDAPYPARLFHVKGRRNIRIRQVEVGVGSMNKGDCFILDC 165
Query: 369 EKKIYQFNGCNS 404
++Y + G +S
Sbjct: 166 GSQVYAYMGPSS 177
Score = 87.4 bits (215), Expect = 1e-17
Identities = 58/135 (42%), Positives = 81/135 (60%), Gaps = 9/135 (6%)
Frame = +3
Query: 39 YDVHFWIGKDSSQDEAGTAAIKTVELDSVLGGRAVQYRELQGYESDKFLSYFKPCIIPME 218
Y ++FW G SSQDE ++AI TV LD+ L G+AVQ R +QGYE FL FK ++
Sbjct: 447 YILYFWQGCASSQDEKASSAIHTVRLDNELCGKAVQVRVVQGYEPAHFLRIFKGRMVIFL 506
Query: 219 GGFASGFK-TPEEETFE---TRLYICKG-----KRAIRIKQVPFARSSLNHDDVFILDTE 371
GG ASGFK + +T++ TRL+ +G RAI+ +V SLN DDVF+L+T
Sbjct: 507 GGKASGFKNVHDHDTYDVDGTRLFRVRGTCDFDTRAIQQTEV---AGSLNSDDVFVLETP 563
Query: 372 KKIYQFNGCNSNIQE 416
K Y + G ++ +E
Sbjct: 564 GKTYLWIGKGASEEE 578
Score = 37.7 bits (86), Expect = 0.011
Identities = 37/126 (29%), Positives = 61/126 (48%), Gaps = 3/126 (2%)
Frame = +3
Query: 48 HFWIGKDSSQDEAGTAAIKTVELDSVLGGRAVQYRELQGYESDKFLSYFKPCIIPMEGGF 227
+ WIGK +S++E K VEL V GR + +G E D F + +G +
Sbjct: 567 YLWIGKGASEEEKAMGE-KVVEL--VSPGRDM-VTVAEGEEDDDFWGG-----LGGKGDY 617
Query: 228 ASGFKTPEEETFETRLYICKGKRA--IRIKQVP-FARSSLNHDDVFILDTEKKIYQFNGC 398
+ + + RL+ C A +R+ ++ FA+ LN DDV +LD+ ++Y + G
Sbjct: 618 QTA-RDLDRPLLYPRLFHCTISPAGCLRVNEMSDFAQEDLNEDDVMVLDSGDEVYVWVGQ 676
Query: 399 NSNIQE 416
S+ QE
Sbjct: 677 GSDDQE 682
>VILI_MOUSE (Q62468) Villin-1|
Length = 826
Score = 120 bits (300), Expect = 2e-27
Identities = 64/127 (50%), Positives = 82/127 (64%), Gaps = 1/127 (0%)
Frame = +3
Query: 39 YDVHFWIGKDSSQDEAGTAAIKTVELDSVLGGRAVQYRELQGYESDKFLSYFKPCIIPME 218
YD+H+WIG+DSSQDE G AAI T ++D L GRAVQ+RE+QG ES+ F SYFK ++ +
Sbjct: 59 YDIHYWIGQDSSQDEQGAAAIYTTQMDDYLKGRAVQHREVQGNESETFRSYFKQGLVIRK 118
Query: 219 GGFASGFKTPEEETFET-RLYICKGKRAIRIKQVPFARSSLNHDDVFILDTEKKIYQFNG 395
GG ASG K E + + RL KGKR + +V + S N DVF+LD K I Q+NG
Sbjct: 119 GGVASGMKHVETNSCDVQRLLHVKGKRNVLAGEVEMSWKSFNRGDVFLLDLGKLIIQWNG 178
Query: 396 CNSNIQE 416
SN E
Sbjct: 179 PESNRME 185
Score = 59.3 bits (142), Expect = 3e-09
Identities = 43/130 (33%), Positives = 62/130 (47%), Gaps = 4/130 (3%)
Frame = +3
Query: 39 YDVHFWIGKDSSQDEAGTAAIKTVELDSVLGGRAVQYRELQGYESDKFLSYFKPCIIPME 218
Y ++ W G +SQDE +A + V LD VQ R G E +S FK ++ +
Sbjct: 440 YLLYIWQGSQASQDEIAASAYQAVLLDQKYNDEPVQIRVTMGKEPPHLMSIFKGRMVVYQ 499
Query: 219 GGFASGFKTPEEETFETRLYICKGKRAIRIK--QVPFARSSLNHDDVFILDTEKKIYQF- 389
GG + K E TRL+ +G A K +V +SLN +DVFIL T Y +
Sbjct: 500 GG--TSRKNNLEPVPSTRLFQVRGTNADNTKAFEVTARATSLNSNDVFILKTPSCCYLWC 557
Query: 390 -NGCNSNIQE 416
GC+ + +E
Sbjct: 558 GKGCSGDERE 567
Score = 29.6 bits (65), Expect = 2.9
Identities = 17/46 (36%), Positives = 26/46 (56%), Gaps = 2/46 (4%)
Frame = +3
Query: 285 KGKRAIR-IKQVPFARSSLNHDDVFILDT-EKKIYQFNGCNSNIQE 416
+GK +R + P + L H+D +ILD KI+ + G N+N QE
Sbjct: 261 EGKLVVREVATRPLTQDLLKHEDCYILDQGGLKIFVWKGKNANAQE 306
Score = 28.9 bits (63), Expect = 5.0
Identities = 31/129 (24%), Positives = 53/129 (41%), Gaps = 6/129 (4%)
Frame = +3
Query: 48 HFWIGKDSSQDEAGTAAIKTVELDSVLGGRAVQYRELQGYESDKFLSYFKPCIIPMEGGF 227
+ W GK S DE A + D++ R + ++G E F GG
Sbjct: 554 YLWCGKGCSGDEREMAKMVA---DTI--SRTEKQVVVEGQEPANFWMAL--------GGK 600
Query: 228 ASGFKTP----EEETFETRLYICKGK--RAIRIKQVPFARSSLNHDDVFILDTEKKIYQF 389
A T E + RL+ C + R + + F + L +DVF+LD +++ +
Sbjct: 601 APYANTKRLQEENQVITPRLFECSNQTGRFLATEIFDFNQDDLEEEDVFLLDVWDQVFFW 660
Query: 390 NGCNSNIQE 416
G ++N +E
Sbjct: 661 IGKHANEEE 669
>VILI_CHICK (P02640) Villin-1|
Length = 826
Score = 119 bits (297), Expect = 4e-27
Identities = 63/139 (45%), Positives = 87/139 (62%), Gaps = 1/139 (0%)
Frame = +3
Query: 3 LQTTSPKGGAYLYDVHFWIGKDSSQDEAGTAAIKTVELDSVLGGRAVQYRELQGYESDKF 182
L +T G + Y++H+W+GK+SSQDE G AAI T ++D LG AVQ+RE+QG+ES+ F
Sbjct: 48 LLSTRKTGSGFSYNIHYWLGKNSSQDEQGAAAIYTTQMDEYLGSVAVQHREVQGHESETF 107
Query: 183 LSYFKPCIIPMEGGFASGFKTPEEETFET-RLYICKGKRAIRIKQVPFARSSLNHDDVFI 359
+YFK +I +GG ASG K E T+ RL KGK+ + +V + S N DVF+
Sbjct: 108 RAYFKQGLIYKQGGVASGMKHVETNTYNVQRLLHVKGKKNVVAAEVEMSWKSFNLGDVFL 167
Query: 360 LDTEKKIYQFNGCNSNIQE 416
LD + I Q+NG SN E
Sbjct: 168 LDLGQLIIQWNGPESNRAE 186
Score = 57.4 bits (137), Expect = 1e-08
Identities = 39/128 (30%), Positives = 59/128 (46%), Gaps = 4/128 (3%)
Frame = +3
Query: 45 VHFWIGKDSSQDEAGTAAIKTVELDSVLGGRAVQYRELQGYESDKFLSYFKPCIIPMEGG 224
++ W G+ +S DE +A + V LD VQ R G E ++ FK ++ E G
Sbjct: 443 IYIWQGRHASTDELAASAYQAVFLDQKYNNEPVQVRVTMGKEPAHLMAIFKGKMVVYENG 502
Query: 225 FASGFKTPEEETFETRLYICKGKRAIRIK--QVPFARSSLNHDDVFILDTEKKIYQF--N 392
+ T E TRL+ G K +VP +SLN +DVF+L T Y +
Sbjct: 503 SSRAGGT--EPASSTRLFHVHGTNEYNTKAFEVPVRAASLNSNDVFVLKTPSSCYLWYGK 560
Query: 393 GCNSNIQE 416
GC+ + +E
Sbjct: 561 GCSGDERE 568
Score = 31.6 bits (70), Expect = 0.78
Identities = 18/58 (31%), Positives = 31/58 (53%), Gaps = 2/58 (3%)
Frame = +3
Query: 249 EEETFETRLYICKGK--RAIRIKQVPFARSSLNHDDVFILDTEKKIYQFNGCNSNIQE 416
E + RL+ C K R + + V F + L+ +DV++LDT +I+ + G +N E
Sbjct: 613 ENPSVPPRLFECSNKTGRFLATEIVDFTQDDLDENDVYLLDTWDQIFFWIGKGANESE 670
>AVIL_MOUSE (O88398) Advillin (p92) (Actin-binding protein DOC6)|
Length = 819
Score = 117 bits (294), Expect = 8e-27
Identities = 67/137 (48%), Positives = 82/137 (59%), Gaps = 1/137 (0%)
Frame = +3
Query: 9 TTSPKGGAYLYDVHFWIGKDSSQDEAGTAAIKTVELDSVLGGRAVQYRELQGYESDKFLS 188
+T G ++HFWIGKDSSQDE AAI T +LD LGG VQ+RE+Q +ESD F
Sbjct: 47 STRRVGSLLSQNIHFWIGKDSSQDEQSCAAIYTTQLDDYLGGSPVQHREVQYHESDTFRG 106
Query: 189 YFKPCIIPMEGGFASGFKTPEEETFET-RLYICKGKRAIRIKQVPFARSSLNHDDVFILD 365
YFK II +GG ASG K E T++ RL KGKR I+ +V + S N DVF+LD
Sbjct: 107 YFKQGIIYKKGGVASGMKHVETNTYDVKRLLHVKGKRNIQATEVEMSWDSFNRGDVFLLD 166
Query: 366 TEKKIYQFNGCNSNIQE 416
I Q+NG SN E
Sbjct: 167 LGMVIIQWNGPESNSGE 183
Score = 57.4 bits (137), Expect = 1e-08
Identities = 41/128 (32%), Positives = 64/128 (50%), Gaps = 2/128 (1%)
Frame = +3
Query: 39 YDVHFWIGKDSSQDEAGTAAIKTVELDSVLGGRAVQYRELQGYESDKFLSYFKPCIIPME 218
Y ++ W G+ +S+DE +A + VE+D VQ R G E F++ FK ++ E
Sbjct: 438 YILYIWQGRHASRDELAASAYRAVEVDQQFDRAPVQVRVSMGKEPRHFMAIFKGKLVIYE 497
Query: 219 GGFASGFKTPEEETFETRLYICKG--KRAIRIKQVPFARSSLNHDDVFILDTEKKIYQFN 392
GG + K EE RL+ G K + +V + SSL +DVF+L T+ + Y +
Sbjct: 498 GG--TSRKGNEEPDPPVRLFQIHGNDKSNTKAVEVSASASSLISNDVFLLRTQAEHYLWY 555
Query: 393 GCNSNIQE 416
G S+ E
Sbjct: 556 GKGSSGDE 563
>VILI_HUMAN (P09327) Villin-1|
Length = 826
Score = 115 bits (287), Expect = 5e-26
Identities = 61/127 (48%), Positives = 80/127 (62%), Gaps = 1/127 (0%)
Frame = +3
Query: 39 YDVHFWIGKDSSQDEAGTAAIKTVELDSVLGGRAVQYRELQGYESDKFLSYFKPCIIPME 218
YD+H+WIG+DSS DE G AAI T ++D L GRAVQ+RE+QG ES+ F YFK ++ +
Sbjct: 59 YDIHYWIGQDSSLDEQGAAAIYTTQMDDFLKGRAVQHREVQGNESEAFRGYFKQGLVIRK 118
Query: 219 GGFASGFKTPEEETFET-RLYICKGKRAIRIKQVPFARSSLNHDDVFILDTEKKIYQFNG 395
GG ASG K E +++ RL KGKR + +V + S N DVF+LD K I Q+NG
Sbjct: 119 GGVASGMKHVETNSYDVQRLLHVKGKRNVVAGEVEMSWKSFNRGDVFLLDLGKLIIQWNG 178
Query: 396 CNSNIQE 416
S E
Sbjct: 179 PESTRME 185
Score = 59.3 bits (142), Expect = 3e-09
Identities = 44/131 (33%), Positives = 66/131 (50%), Gaps = 5/131 (3%)
Frame = +3
Query: 39 YDVHFWIGKDSSQDEAGTAAIKTVELDSVLGGRAVQYRELQGYESDKFLSYFKPCIIPME 218
Y ++ W G +SQDE +A + V LD G VQ R G E +S FK ++ +
Sbjct: 440 YLLYVWQGSQASQDEITASAYQAVILDQKYNGEPVQIRVPMGKEPPHLMSIFKGRMVVYQ 499
Query: 219 GGFASGFKTPEEETF-ETRLYICKGKRAIRIK--QVPFARSSLNHDDVFILDTEKKIYQF 389
GG + +T ET TRL+ +G A K +VP + LN +DVF+L T+ Y +
Sbjct: 500 GGTS---RTNNLETGPSTRLFQVQGTGANNTKAFEVPARANFLNSNDVFVLKTQSCCYLW 556
Query: 390 --NGCNSNIQE 416
GC+ + +E
Sbjct: 557 CGKGCSGDERE 567
Score = 31.6 bits (70), Expect = 0.78
Identities = 32/126 (25%), Positives = 56/126 (44%), Gaps = 3/126 (2%)
Frame = +3
Query: 48 HFWIGKDSSQDEAGTAAIKTVELDSVLGGRAVQYRELQGYESDKFLSYFKPCIIPMEGGF 227
+ W GK S DE A + D++ R + ++G E F + + +
Sbjct: 554 YLWCGKGCSGDEREMAKMVA---DTI--SRTEKQVVVEGQEPANFWM-----ALGGKAPY 603
Query: 228 ASGFKTPEEETFET-RLYICKGK--RAIRIKQVPFARSSLNHDDVFILDTEKKIYQFNGC 398
A+ + EE T RL+ C K R + + F + L DDVF+LD +++ + G
Sbjct: 604 ANTKRLQEENLVITPRLFECSNKTGRFLATEIPDFNQDDLEEDDVFLLDVWDQVFFWIGK 663
Query: 399 NSNIQE 416
++N +E
Sbjct: 664 HANEEE 669
>ADSV_HUMAN (Q9Y6U3) Adseverin (Scinderin)|
Length = 715
Score = 111 bits (278), Expect = 6e-25
Identities = 60/136 (44%), Positives = 81/136 (59%), Gaps = 1/136 (0%)
Frame = +3
Query: 12 TSPKGGAYLYDVHFWIGKDSSQDEAGTAAIKTVELDSVLGGRAVQYRELQGYESDKFLSY 191
T+ + Y +HFW+GK+ SQDE+ AAI TV++D LGG+ VQ RELQGYES+ F+SY
Sbjct: 51 TAKTSRGFTYHLHFWLGKECSQDESTAAAIFTVQMDDYLGGKPVQNRELQGYESNDFVSY 110
Query: 192 FKPCIIPMEGGFASGFK-TPEEETFETRLYICKGKRAIRIKQVPFARSSLNHDDVFILDT 368
FK + GG ASG + RL KG+R +R +VP + S N D FI+D
Sbjct: 111 FKGGLKYKAGGVASGLNHVLTNDLTAKRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDL 170
Query: 369 EKKIYQFNGCNSNIQE 416
+IYQ+ G + N E
Sbjct: 171 GTEIYQWCGSSCNKYE 186
Score = 62.4 bits (150), Expect = 4e-10
Identities = 43/110 (39%), Positives = 59/110 (53%), Gaps = 4/110 (3%)
Frame = +3
Query: 45 VHFWIGKDSSQDEAGTAAIKTVELDSVLGGRAVQYRELQGYESDKFLSYF--KPCIIPME 218
++ W G ++++DE T+A TV+LD LGG+AVQ R QG E LS F KP II
Sbjct: 437 IYTWQGANATRDELTTSAFLTVQLDRSLGGQAVQIRVSQGKEPVHLLSLFKDKPLIIYKN 496
Query: 219 GGFASGFKTPEEET--FETRLYICKGKRAIRIKQVPFARSSLNHDDVFIL 362
G G + P T F+ R + RI +V +SLN +DVF+L
Sbjct: 497 GTSKKGGQAPAPPTRLFQVRRNLAS---ITRIVEVDVDANSLNSNDVFVL 543
Score = 35.8 bits (81), Expect = 0.041
Identities = 35/127 (27%), Positives = 60/127 (47%), Gaps = 7/127 (5%)
Frame = +3
Query: 48 HFWIGKDSSQDEAGTAAIKTVELDSVLGGRAVQYRELQGYESDKFLSYFKPCIIPMEGGF 227
+ W+GK +SQ+E A + SVL + ++ +E G E ++F + GG
Sbjct: 551 YIWVGKGASQEEEKGAEY----VASVLKCKTLRIQE--GEEPEEFWNSL--------GGK 596
Query: 228 ASGFKTP----EEETFETRLYICKGKRA-IRIKQVP--FARSSLNHDDVFILDTEKKIYQ 386
+P + E RLY C K I+++P F + L DDV +LD ++I+
Sbjct: 597 KDYQTSPLLETQAEDHPPRLYGCSNKTGRFVIEEIPGEFTQDDLAEDDVMLLDAWEQIFI 656
Query: 387 FNGCNSN 407
+ G ++N
Sbjct: 657 WIGKDAN 663
>ADSV_MOUSE (Q60604) Adseverin (Scinderin) (Gelsolin-like protein)|
Length = 715
Score = 109 bits (273), Expect = 2e-24
Identities = 62/139 (44%), Positives = 81/139 (58%), Gaps = 1/139 (0%)
Frame = +3
Query: 3 LQTTSPKGGAYLYDVHFWIGKDSSQDEAGTAAIKTVELDSVLGGRAVQYRELQGYESDKF 182
L TT G + Y +HFW+GK+ SQDE+ AAI TV++D LGG+ VQ RELQGYES F
Sbjct: 49 LHTTKSSRG-FSYRLHFWLGKECSQDESTAAAIFTVQMDDYLGGKPVQSRELQGYESTDF 107
Query: 183 LSYFKPCIIPMEGGFASGFK-TPEEETFETRLYICKGKRAIRIKQVPFARSSLNHDDVFI 359
+ YFK + GG ASG + RL KG+R +R +VP + S N D FI
Sbjct: 108 VGYFKGGLKYKAGGVASGLNHVLTNDLTAKRLLHVKGRRVVRATEVPLSWESFNKGDCFI 167
Query: 360 LDTEKKIYQFNGCNSNIQE 416
+D +IYQ+ G + N E
Sbjct: 168 IDLGTEIYQWCGSSCNKYE 186
Score = 55.8 bits (133), Expect = 4e-08
Identities = 40/110 (36%), Positives = 56/110 (50%), Gaps = 4/110 (3%)
Frame = +3
Query: 45 VHFWIGKDSSQDEAGTAAIKTVELDSVLGGRAVQYRELQGYESDKFLSYF--KPCIIPME 218
++ W G ++++DE +A TV+LD LGG+AVQ R QG E LS F KP II
Sbjct: 437 IYTWQGANATRDELTMSAFLTVQLDRSLGGQAVQVRVSQGKEPAHLLSLFKDKPLIIYKN 496
Query: 219 GGFASGFKTPEEET--FETRLYICKGKRAIRIKQVPFARSSLNHDDVFIL 362
G + P T F+ R + RI +V +SLN +D F+L
Sbjct: 497 GTSKKEGQAPAPPTRLFQVRRNLAS---ITRIVEVDVDANSLNSNDTFVL 543
Score = 34.7 bits (78), Expect = 0.092
Identities = 38/125 (30%), Positives = 58/125 (46%), Gaps = 7/125 (5%)
Frame = +3
Query: 54 WIGKDSSQDEAGTAAIKTVELDSVLGGRAVQYRELQGYESDKFLSYFKPCIIPMEGGFAS 233
WIGK +SQ+E A + VL +A + +E G E ++F + GG
Sbjct: 553 WIGKGASQEEEKGAEY----VADVLKCKASRIQE--GKEPEEFWNSL--------GGRGD 598
Query: 234 GFKTPEEET----FETRLYICKGKRA-IRIKQVP--FARSSLNHDDVFILDTEKKIYQFN 392
+P ET RLY C K I++VP F + L DDV +LD ++I+ +
Sbjct: 599 YQTSPLLETRAEDHPPRLYGCSNKTGRFIIEEVPGEFTQDDLAEDDVMLLDAWEQIFIWI 658
Query: 393 GCNSN 407
G ++N
Sbjct: 659 GKDAN 663
>ADSV_BOVIN (Q28046) Adseverin (Scinderin) (SC)|
Length = 715
Score = 108 bits (271), Expect = 4e-24
Identities = 61/139 (43%), Positives = 81/139 (58%), Gaps = 1/139 (0%)
Frame = +3
Query: 3 LQTTSPKGGAYLYDVHFWIGKDSSQDEAGTAAIKTVELDSVLGGRAVQYRELQGYESDKF 182
L TT G + Y +HFW+GK+ +QDE+ AAI TV++D LGG+ VQ RELQGYES F
Sbjct: 49 LHTTQASRG-FTYRLHFWLGKECTQDESTAAAIFTVQMDDYLGGKPVQNRELQGYESTDF 107
Query: 183 LSYFKPCIIPMEGGFASGFK-TPEEETFETRLYICKGKRAIRIKQVPFARSSLNHDDVFI 359
+ YFK + GG ASG + RL KG+R +R +VP + S N D FI
Sbjct: 108 VGYFKGGLKYKAGGVASGLNHVLTNDLTAQRLLHVKGRRVVRATEVPLSWDSFNKGDCFI 167
Query: 360 LDTEKKIYQFNGCNSNIQE 416
+D +IYQ+ G + N E
Sbjct: 168 IDLGTEIYQWCGSSCNKYE 186
Score = 59.7 bits (143), Expect = 3e-09
Identities = 45/121 (37%), Positives = 62/121 (51%), Gaps = 4/121 (3%)
Frame = +3
Query: 45 VHFWIGKDSSQDEAGTAAIKTVELDSVLGGRAVQYRELQGYESDKFLSYF--KPCIIPME 218
++ W G ++++DE T+A TV+LD LGG+AVQ R QG E LS F KP II
Sbjct: 437 IYTWQGANATRDELTTSAFLTVQLDRSLGGQAVQIRVSQGKEPAHLLSLFKDKPLIIYKN 496
Query: 219 GGFASGFKTPEE--ETFETRLYICKGKRAIRIKQVPFARSSLNHDDVFILDTEKKIYQFN 392
G + P F+ R + RI +V +SLN +DVF+L K+ Q N
Sbjct: 497 GTSKKEGQAPAPPIRLFQVRRNLAS---ITRIMEVDVDANSLNSNDVFVL----KLRQNN 549
Query: 393 G 395
G
Sbjct: 550 G 550
Score = 34.7 bits (78), Expect = 0.092
Identities = 37/127 (29%), Positives = 58/127 (45%), Gaps = 7/127 (5%)
Frame = +3
Query: 48 HFWIGKDSSQDEAGTAAIKTVELDSVLGGRAVQYRELQGYESDKFLSYFKPCIIPMEGGF 227
+ WIGK S+Q+E A + SVL + +E G E ++F + GG
Sbjct: 551 YIWIGKGSTQEEEKGAEY----VASVLKCKTSTIQE--GKEPEEFWNSL--------GGK 596
Query: 228 ASGFKTP----EEETFETRLYICKGKRA-IRIKQVP--FARSSLNHDDVFILDTEKKIYQ 386
+P + E RLY C K I++VP F + L DDV +LD ++I+
Sbjct: 597 KDYQTSPLLESQAEDHPPRLYGCSNKTGRFIIEEVPGEFTQDDLAEDDVMLLDAWEQIFI 656
Query: 387 FNGCNSN 407
+ G ++N
Sbjct: 657 WIGKDAN 663
>VILL_HUMAN (O15195) Villin-like protein|
Length = 856
Score = 94.7 bits (234), Expect = 7e-20
Identities = 50/126 (39%), Positives = 72/126 (57%), Gaps = 1/126 (0%)
Frame = +3
Query: 42 DVHFWIGKDSSQDEAGTAAIKTVELDSVLGGRAVQYRELQGYESDKFLSYFKPCIIPMEG 221
D+H+W+GK + + G A L LGG+ V +RE QG+ESD F SYF+P II +G
Sbjct: 59 DLHYWVGKQAGAEAQGAAEAFQQRLQDELGGQTVLHREAQGHESDCFCSYFRPGIIYRKG 118
Query: 222 GFASGFKTPEEETFE-TRLYICKGKRAIRIKQVPFARSSLNHDDVFILDTEKKIYQFNGC 398
G AS K E F RL KG++ + +V + +S N D+F+LD K + Q+NG
Sbjct: 119 GLASDLKHVETNLFNIQRLLHIKGRKHVSATEVELSWNSFNKGDIFLLDLGKMMIQWNGP 178
Query: 399 NSNIQE 416
++I E
Sbjct: 179 KTSISE 184
Score = 52.4 bits (124), Expect = 4e-07
Identities = 39/134 (29%), Positives = 59/134 (44%), Gaps = 4/134 (2%)
Frame = +3
Query: 27 GAYLYDVHFWIGKDSSQDEAGTAAIKTVELDSVLGGRAVQYRELQGYESDKFLSYFKPCI 206
G Y ++ W G ++ DE ELD + GG VQ G E FL+ F+ +
Sbjct: 430 GRVQYILYLWQGHQATADEIEALNSNAEELDVMYGGVLVQEHVTMGSEPPHFLAIFQGQL 489
Query: 207 IPMEGGFASGFKTPEEETFETRLYICKG--KRAIRIKQVPFARSSLNHDDVFILDTEKKI 380
+ + +G + TRL+ +G R +VP SSLN D+F+L T
Sbjct: 490 VIFQE--RAGHHGKGQSASTTRLFQVQGTDSHNTRTMEVPARASSLNSSDIFLLVTASVC 547
Query: 381 YQF--NGCNSNIQE 416
Y + GCN + +E
Sbjct: 548 YLWFGKGCNGDQRE 561
>GELS_HALRO (O61270) Gelsolin, cytoplasmic (Actin-depolymerizing factor) (ADF)|
(Ascidian gelsolin)
Length = 715
Score = 94.7 bits (234), Expect = 7e-20
Identities = 57/134 (42%), Positives = 79/134 (58%), Gaps = 3/134 (2%)
Frame = +3
Query: 3 LQTTSPKGG-AYLYDVHFWIGKDSSQDEAGTAAIKTVELDSVLGGRAVQYRELQGYESDK 179
L+TT+ + G + +++H+W GK+SSQDE G AI V++D L G V++RE+QG ES
Sbjct: 46 LKTTALESGRGFEWNLHYWQGKESSQDERGAVAILAVKMDDHLNGGPVEHREVQGNESAA 105
Query: 180 FLSYFKPCIIPMEGGFASGFKTPEEETFETR--LYICKGKRAIRIKQVPFARSSLNHDDV 353
F F P I + GG ASGF E E R L KGKR +R QVP +SL D
Sbjct: 106 FKGLF-PTITYLIGGVASGFTHVEINEVEDRKVLTRVKGKRPVRATQVPIKWTSLTDSDS 164
Query: 354 FILDTEKKIYQFNG 395
++ D K+IY ++G
Sbjct: 165 YVFDIGKEIYVWSG 178
Score = 39.7 bits (91), Expect = 0.003
Identities = 38/132 (28%), Positives = 62/132 (46%), Gaps = 5/132 (3%)
Frame = +3
Query: 15 SPKGGAYLYDVHFWIGKDSSQDEAGTAAIKTVEL-DSVLGGRAVQYRELQGYESDKFLSY 191
+P+ GA + +++W G +S +E I+T ++ G A Q R +QG E +
Sbjct: 429 TPQRGANV--LYYWQGNKASINERTALPIQTKNTHETECDGNASQIRVVQGTEPPHMMML 486
Query: 192 F--KPCIIPMEGGFASGFKTPEEETFETRLYICKGKRAIRIK--QVPFARSSLNHDDVFI 359
F KP I+ + + T + + TRLY + A R + +VP S LN +D F+
Sbjct: 487 FGGKPLIVHLGDTISP---TGKSKAASTRLYQVQSFFAGRCRAVEVPAKSSHLNSNDAFL 543
Query: 360 LDTEKKIYQFNG 395
L T Y + G
Sbjct: 544 LITPSGSYIWVG 555
>FLII_MOUSE (Q9JJ28) Protein flightless-1 homolog|
Length = 1271
Score = 88.2 bits (217), Expect = 7e-18
Identities = 49/136 (36%), Positives = 77/136 (56%)
Frame = +3
Query: 3 LQTTSPKGGAYLYDVHFWIGKDSSQDEAGTAAIKTVELDSVLGGRAVQYRELQGYESDKF 182
L+T G+ +++++WIG +++ D+ +AI V L + LG RE G ES++F
Sbjct: 531 LKTFLDDSGSLNWEIYYWIGGEATLDKKACSAIHAVNLRNYLGAECRTVREEMGDESEEF 590
Query: 183 LSYFKPCIIPMEGGFASGFKTPEEETFETRLYICKGKRAIRIKQVPFARSSLNHDDVFIL 362
L F I +EGG ASGF T E+ + TR+Y GK+ I+++ VP SSL+ VF+L
Sbjct: 591 LQVFDNDISYIEGGTASGFYTVEDTHYVTRMYRVYGKKNIKLEPVPLKGSSLDPRFVFLL 650
Query: 363 DTEKKIYQFNGCNSNI 410
D IY + G + +
Sbjct: 651 DQGLDIYVWRGAQATL 666
Score = 34.7 bits (78), Expect = 0.092
Identities = 31/125 (24%), Positives = 52/125 (41%), Gaps = 4/125 (3%)
Frame = +3
Query: 45 VHFWIGKDSSQDEAGTAA-IKTVELDSVLGGRAVQYRELQGYESDKFLSYFKPCIIPMEG 221
V+ W+G+ S DEA A I D+ + + +G E + F +
Sbjct: 1103 VYAWVGRASDPDEAKLAEDILNTMFDASYSKQVIN----EGEEPENFFW--------VGI 1150
Query: 222 GFASGFKTPEEETFETRLYIC---KGKRAIRIKQVPFARSSLNHDDVFILDTEKKIYQFN 392
G + E TRL+ C KG A+ K F + L DD+ +LD +++Y +
Sbjct: 1151 GAQKPYDDDAEYMKHTRLFRCSNEKGYFAVTEKCSDFCQDDLADDDIMLLDNGQEVYMWV 1210
Query: 393 GCNSN 407
G ++
Sbjct: 1211 GTQTS 1215
Score = 28.5 bits (62), Expect = 6.6
Identities = 30/110 (27%), Positives = 46/110 (41%), Gaps = 4/110 (3%)
Frame = +3
Query: 45 VHFWIGKDSSQDEAGTAAIKTVE-LDSVLGGRAVQYRELQGYESDKFLSYFKPCIIPMEG 221
V+FW G+++S T + +S+ G+ R Q E+ KFLS+FK I
Sbjct: 986 VYFWQGREASNMGWLTFTFSLQKKFESLFPGKLEVVRMTQQQENPKFLSHFKRKFI---- 1041
Query: 222 GFASGFKTPEEETFETRLYICK---GKRAIRIKQVPFARSSLNHDDVFIL 362
G + + T + LY + R Q+ S LN + FIL
Sbjct: 1042 -IHRGKRKVTQGTLQPTLYQIRTNGSALCTRCIQINTDSSLLNSEFCFIL 1090
>VILL_MOUSE (Q91YD6) Villin-like protein (EF-6)|
Length = 859
Score = 87.4 bits (215), Expect = 1e-17
Identities = 52/127 (40%), Positives = 75/127 (59%), Gaps = 2/127 (1%)
Frame = +3
Query: 42 DVHFWIGKDSSQDEAGTAAIKTVE-LDSVLGGRAVQYRELQGYESDKFLSYFKPCIIPME 218
D+H+WIGKD+S EA AA+ V+ L LG + V +RE QG+ESD F SYF P +I +
Sbjct: 61 DLHYWIGKDASA-EAREAAVSFVQCLQEDLGDQTVLHRESQGHESDCFHSYFHPGVIYRK 119
Query: 219 GGFASGFKTPEEETFET-RLYICKGKRAIRIKQVPFARSSLNHDDVFILDTEKKIYQFNG 395
GG S K E + RL KG++ + +V + +S N D+F+LD K + Q+NG
Sbjct: 120 GGRDSALKFAETNMYNVQRLLHIKGRKHVSATEVALSWNSFNKGDIFLLDLGKVMIQWNG 179
Query: 396 CNSNIQE 416
++I E
Sbjct: 180 PKASISE 186
Score = 48.9 bits (115), Expect = 5e-06
Identities = 39/139 (28%), Positives = 60/139 (43%), Gaps = 4/139 (2%)
Frame = +3
Query: 12 TSPKGGAYLYDVHFWIGKDSSQDEAGTAAIKTVELDSVLGGRAVQYRELQGYESDKFLSY 191
T K G Y ++ W G S+ ++ ELD + G Q G E FL+
Sbjct: 425 TYQKLGCVQYLLYLWQGHQSTVEDTKALNCSAEELDLMHQGALAQGHVTMGSEPPHFLAI 484
Query: 192 FKPCIIPMEGGFASGFKTPEEETFETRLYICKGKRA--IRIKQVPFARSSLNHDDVFILD 365
F+ ++ +G +G K +TRL+ +G + R +VP SSL DVF L
Sbjct: 485 FQGRLVVFQGN--AGNKGERPPVSDTRLFHVQGTESHNTRTMEVPARASSLTSGDVFFLI 542
Query: 366 TEKKIYQF--NGCNSNIQE 416
T Y + GC+ + +E
Sbjct: 543 TSHVCYLWFGKGCHGDQRE 561
>FLII_DROME (Q24020) Protein flightless-1 (Flightless-I)|
Length = 1256
Score = 75.9 bits (185), Expect = 4e-14
Identities = 52/133 (39%), Positives = 74/133 (55%), Gaps = 2/133 (1%)
Frame = +3
Query: 3 LQTTSPKGGAYLYDVHFWIGKDSSQDEAGTAAIKTVELDSVLGGRAVQYRELQGYESDKF 182
L+T G +++ FWIG +++ D+ AAI V L + LG R RE QG ES++F
Sbjct: 529 LKTKFDDLGLLDWEIFFWIGNEATLDKRACAAIHAVNLRNFLGARCRTVREEQGDESEQF 588
Query: 183 LSYFKPCIIPMEGG-FASGFKTPEEETFETRLYICKGKRA-IRIKQVPFARSSLNHDDVF 356
LS F+ +I +EGG A+GF T EE TRLY+ A I ++ V A +SL+ F
Sbjct: 589 LSLFETEVIYIEGGRTATGFYTIEEMIHITRLYLVHAYGATIHLEPVAPAITSLDPRHAF 648
Query: 357 ILDTEKKIYQFNG 395
+LD IY + G
Sbjct: 649 VLDLGTHIYIWMG 661
Score = 28.9 bits (63), Expect = 5.0
Identities = 30/122 (24%), Positives = 51/122 (41%), Gaps = 5/122 (4%)
Frame = +3
Query: 45 VHFWIGKDSSQDEAGTAAIKTVE--LDSVLGGRAVQYRELQGYESDKFLSYFKPCIIPME 218
V+ WIG + +EA K V+ + + V + L E D+ ++F +
Sbjct: 1088 VYVWIGSKACNEEA-----KLVQDIAEQMFNSPWVSLQILN--EGDEPENFFWVAL---- 1136
Query: 219 GGFASGFKTPEEETFETRLYICKGKRA---IRIKQVPFARSSLNHDDVFILDTEKKIYQF 389
G + T E TRL+ C +R + K F + L DD+ ILD + ++ +
Sbjct: 1137 -GGRKPYDTDAEYMNYTRLFRCSNERGYYTVAEKCADFCQDDLADDDIMILDNGEHVFLW 1195
Query: 390 NG 395
G
Sbjct: 1196 MG 1197
>VILI_DICDI (P36418) Protovillin (100 kDa actin-binding protein)|
Length = 959
Score = 74.3 bits (181), Expect = 1e-13
Identities = 50/142 (35%), Positives = 73/142 (51%), Gaps = 19/142 (13%)
Frame = +3
Query: 39 YDVHFWIGK--DSSQDEAGTAAIKTVELDSVLGGRAVQ------------YRELQGYESD 176
Y++HFWIG+ +SQ+ + EL+ ++ Q YRE QG E D
Sbjct: 100 YNIHFWIGELLINSQETINFCNDRIEELERIIKYNQKQFDSEQFYPEPILYREFQGKEGD 159
Query: 177 KFLSYFKPC-----IIPMEGGFASGFKTPEEETFETRLYICKGKRAIRIKQVPFARSSLN 341
F+SYFK + P++ AS + + +L+ KG+R IR+KQV + SLN
Sbjct: 160 IFMSYFKSYGGPRYVAPLKLTSASAAIATAAKQY--KLFHLKGRRNIRVKQVDISSKSLN 217
Query: 342 HDDVFILDTEKKIYQFNGCNSN 407
DVF+LD E IYQ+NG S+
Sbjct: 218 SGDVFVLDCEDFIYQWNGSESS 239
Score = 36.2 bits (82), Expect = 0.031
Identities = 32/126 (25%), Positives = 62/126 (49%), Gaps = 3/126 (2%)
Frame = +3
Query: 48 HFWIGKDSSQDEAGTAAIKTVELDSVLGGRAVQYRELQGYESDKFLSYFKP-CIIPMEGG 224
+ W+GK S + EA +V G Q + +G E+ +F + + +
Sbjct: 634 YIWVGKYSDEKEAALQISS-----NVFTGYNFQLID-EGDETSEFWESLETNSSLSLLKD 687
Query: 225 FASGFKTPEEETFETRLYICKGKRAI-RIKQV-PFARSSLNHDDVFILDTEKKIYQFNGC 398
+ + +T E+E +TRL+ C + ++ ++ F++ L+ DDV ILD +K+I+ + G
Sbjct: 688 YYTQLRTVEQEK-KTRLFQCSNNSGVFKVFEIHDFSQDDLDSDDVMILDNQKQIFVWVGK 746
Query: 399 NSNIQE 416
S+ E
Sbjct: 747 ESSDTE 752
>FLII_CAEEL (P34268) Protein flightless-1 homolog|
Length = 1257
Score = 62.8 bits (151), Expect = 3e-10
Identities = 43/138 (31%), Positives = 71/138 (51%), Gaps = 2/138 (1%)
Frame = +3
Query: 3 LQTTSPKGGAYLYDVHFWIGKDSSQDEAGTAAIKTVELDSVLGGRAVQYRELQGYESDKF 182
L+TT G + + +W+G+ +S D+ +A+ V L + L RE E+++F
Sbjct: 540 LKTTREASGQLRHAIFYWLGEHASLDKGMCSAVHAVGLRNHLNATCRTQREEMNDETEEF 599
Query: 183 LSYFKPCIIPMEGGFA-SGFKTPEEETFETRLYIC-KGKRAIRIKQVPFARSSLNHDDVF 356
L+ F I+ +EGG SGF T E+ TRLY A+ ++ VP + SL+ F
Sbjct: 600 LTLFGEEIVYIEGGRTISGFYTTEKPAHLTRLYRAGVNGTAVEMEPVPLSVESLDPRFCF 659
Query: 357 ILDTEKKIYQFNGCNSNI 410
+LD + I+ ++G S I
Sbjct: 660 LLDAGETIWIWSGYKSRI 677
Score = 42.4 bits (98), Expect = 4e-04
Identities = 35/124 (28%), Positives = 56/124 (45%), Gaps = 3/124 (2%)
Frame = +3
Query: 45 VHFWIGKDSSQDEAGTAAIKTVELDSVLGGRAVQYRELQGYESDKFLSYFKPCIIPMEGG 224
V+ W+GKDS E A + V D V+ +R ++ E ++ ++K G
Sbjct: 1086 VYVWMGKDSDPREHEFA--RQVASDLVVRDDDNDFRIVEVQEGEENEEFWKVL------G 1137
Query: 225 FASGFKTPEEETFETRLYIC---KGKRAIRIKQVPFARSSLNHDDVFILDTEKKIYQFNG 395
++T TRL+ C KG AI K V F + L+ DD+ ILD ++ + G
Sbjct: 1138 GKKKYETDSSFVKHTRLFRCTNEKGYFAISEKTVDFCQDDLDDDDIMILDNGDAVFLWIG 1197
Query: 396 CNSN 407
S+
Sbjct: 1198 ARSS 1201
>VILD_DICDI (Q8WQ85) Villidin|
Length = 1704
Score = 61.2 bits (147), Expect = 9e-10
Identities = 44/119 (36%), Positives = 65/119 (54%), Gaps = 2/119 (1%)
Frame = +3
Query: 45 VHFWIGKDSSQDEAGTAAIKTVELDSVLGGRAVQYRELQGYESDKFLSYFKPCIIPMEGG 224
+++++G+DSS +E GT+A TV+L+ L G VQ R + E FL+ FK ++ +G
Sbjct: 1338 IYYYLGRDSSINEKGTSAYLTVDLNESLVGACVQTRVVANKECKNFLNLFKTKMVIHKG- 1396
Query: 225 FASGFKTPEEETFETRLYICKG--KRAIRIKQVPFARSSLNHDDVFILDTEKKIYQFNG 395
K + + LY KG K IR QV F+ S LN V IL T +KIY ++G
Sbjct: 1397 -----KYNNYDPKKPSLYQVKGLDKIDIRAVQVEFSSSMLNTLHVSILRTPEKIYIWHG 1450
Score = 35.4 bits (80), Expect = 0.054
Identities = 17/41 (41%), Positives = 26/41 (63%)
Frame = +3
Query: 285 KGKRAIRIKQVPFARSSLNHDDVFILDTEKKIYQFNGCNSN 407
KGKR IR++ V + SSLN + FILD +I+ + G ++
Sbjct: 1033 KGKRKIRVRMVKLSTSSLNCHNSFILDAGPRIFVWAGSKTS 1073
Score = 31.6 bits (70), Expect = 0.78
Identities = 31/127 (24%), Positives = 51/127 (40%), Gaps = 10/127 (7%)
Frame = +3
Query: 45 VHFWIGKDSSQDEAGTAAIKTVELDSVLGGRAVQYRELQGYESDKFLSYFKPCIIPMEGG 224
++ W GK S E +A +S + +G ES++F S F+ GG
Sbjct: 1445 IYIWHGKFSLDAEQNSALSIAENFNSTSAPIEILK---EGSESNEFWSAFEST-----GG 1496
Query: 225 FASGFKT--------PEEETFETRLYICKGKRAIR--IKQVPFARSSLNHDDVFILDTEK 374
F P T++ R ++C I ++ PF++ L+ V ILD +
Sbjct: 1497 RQKYFNDIMIQSSSIPTSFTYKPRFFVCSNASGIVEVTEESPFSQDDLDIGSVCILDVQS 1556
Query: 375 KIYQFNG 395
IY + G
Sbjct: 1557 HIYLWIG 1563
>GELS_XENLA (P14885) Gelsolin (Actin-depolymerizing factor) (ADF) (Brevin)|
(Fragment)
Length = 417
Score = 60.1 bits (144), Expect = 2e-09
Identities = 45/131 (34%), Positives = 63/131 (48%), Gaps = 4/131 (3%)
Frame = +3
Query: 24 GGAYLYDVHFWIGKDSSQDEAGTAAIKTVELDSVLGGRAVQYRELQGYESDKFLSYF--K 197
GG ++ W G DS++DE +AI + +LD LGG VQ R +QG E +S F K
Sbjct: 119 GGKQGQIIYTWQGDDSTKDEITASAILSAQLDEELGGGPVQVRVVQGKEPAHLISLFGGK 178
Query: 198 PCIIPMEGGFASGFKTPEEET--FETRLYICKGKRAIRIKQVPFARSSLNHDDVFILDTE 371
P II G G +T + F+ R RA+ +V S+LN +D F+L T
Sbjct: 179 PMIIYKGGTSREGGQTKDANVRLFQVRTSSSGFSRAV---EVDNTASNLNSNDAFVLTTP 235
Query: 372 KKIYQFNGCNS 404
Y + G S
Sbjct: 236 SASYLWVGQGS 246
Score = 30.8 bits (68), Expect = 1.3
Identities = 33/124 (26%), Positives = 52/124 (41%), Gaps = 8/124 (6%)
Frame = +3
Query: 48 HFWIGKDSSQDEAGTAAIKTVELDSVLGGRAVQYRELQGYESDKFLSYFKPCIIPMEGGF 227
+ W+G+ S+ E A EL +LG A + E G E+D F G
Sbjct: 239 YLWVGQGSTNVEKNGAK----ELLKILGVSASEIPE--GQETDDFWGAL---------GG 283
Query: 228 ASGFKTPEE-----ETFETRLYICKGKRA-IRIKQVP--FARSSLNHDDVFILDTEKKIY 383
+ ++T RL+ C K I++VP ++ L DDV +LDT ++Y
Sbjct: 284 KADYRTSARLKDKLNAHPPRLFACSNKTGRFIIEEVPGEISQDDLATDDVMLLDTWDQVY 343
Query: 384 QFNG 395
+ G
Sbjct: 344 VWVG 347
>ARS2_DROME (Q9V9K7) Arsenite-resistance protein 2 homolog|
Length = 943
Score = 28.1 bits (61), Expect = 8.6
Identities = 16/82 (19%), Positives = 37/82 (45%)
Frame = +3
Query: 72 SQDEAGTAAIKTVELDSVLGGRAVQYRELQGYESDKFLSYFKPCIIPMEGGFASGFKTPE 251
S+++ G +T +L + ++ ++D + C+I +EGG K +
Sbjct: 216 SEEQRGFLQRRTDVFMELLENGTIGSVKVDSSQADALIRVLDTCVIKLEGGTDEDLKVLD 275
Query: 252 EETFETRLYICKGKRAIRIKQV 317
E+ + +Y K ++ +K+V
Sbjct: 276 EKPKDPVVYERKAEQMQSVKEV 297
Database: uniprot_sprot.fasta
Posted date: May 25, 2006 5:36 PM
Number of letters in database: 80,573,946
Number of sequences in database: 219,361
Lambda K H
0.318 0.135 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 62,638,696
Number of Sequences: 219361
Number of extensions: 1280378
Number of successful extensions: 4357
Number of sequences better than 10.0: 52
Number of HSP's better than 10.0 without gapping: 4181
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4311
length of database: 80,573,946
effective HSP length: 100
effective length of database: 58,637,846
effective search space used: 2228238148
frameshift window, decay const: 50, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)