Clone Information

BLAST Search Result

Clone Name	bastl08g12
Clone Library Name	barley_pub

No.	Definition	Score (bits)	E Value
1	VILI2_ARATH (O81644) Villin-2	254	7e-68
2	VILI3_ARATH (O81645) Villin-3	244	7e-65
3	VILI4_ARATH (O65570) Villin-4	197	1e-50
4	VILI1_ARATH (O81643) Villin-1	149	2e-36
5	GELS_DROME (Q07171) Gelsolin precursor	74	2e-13
6	AVIL_HUMAN (O75366) Advillin (p92)	72	5e-13
7	GELS_HOMAM (Q27319) Gelsolin, cytoplasmic (Actin-depolymerizing ...	71	1e-12
8	SEVE_DICDI (P10733) Severin	70	2e-12
9	SEVE_ECHGR (Q24800) Severin	67	2e-11
10	FLII_HUMAN (Q13045) Protein flightless-1 homolog	67	2e-11
11	AVIL_MOUSE (O88398) Advillin (p92) (Actin-binding protein DOC6)	67	2e-11
12	FLII_MOUSE (Q9JJ28) Protein flightless-1 homolog	66	3e-11
13	VILI_MOUSE (Q62468) Villin-1	66	3e-11
14	VILI_DICDI (P36418) Protovillin (100 kDa actin-binding protein)	66	3e-11
15	GELS_HORSE (Q28372) Gelsolin (Actin-depolymerizing factor) (ADF)...	65	6e-11
16	GELS_CHICK (O93510) Gelsolin precursor (Actin-depolymerizing fac...	65	8e-11
17	GELS_MOUSE (P13020) Gelsolin precursor (Actin-depolymerizing fac...	65	8e-11
18	GELS_HUMAN (P06396) Gelsolin precursor (Actin-depolymerizing fac...	65	8e-11
19	GELS_PIG (P20305) Gelsolin precursor (Actin-depolymerizing facto...	65	1e-10
20	VILL_HUMAN (O15195) Villin-like protein	60	2e-09
21	VILI_HUMAN (P09327) Villin-1	60	2e-09
22	VILL_MOUSE (Q91YD6) Villin-like protein (EF-6)	60	3e-09
23	VILI_CHICK (P02640) Villin-1	59	7e-09
24	VILD_DICDI (Q8WQ85) Villidin	58	1e-08
25	ADSV_PIG (Q29297) Adseverin (Scinderin) (Fragment)	57	2e-08
26	ADSV_MOUSE (Q60604) Adseverin (Scinderin) (Gelsolin-like protein)	56	4e-08
27	ADSV_BOVIN (Q28046) Adseverin (Scinderin) (SC)	56	4e-08
28	CAPG_MOUSE (P24452) Macrophage capping protein (Myc basic motif ...	56	4e-08
29	ADSV_HUMAN (Q9Y6U3) Adseverin (Scinderin)	55	1e-07
30	GELS_HALRO (O61270) Gelsolin, cytoplasmic (Actin-depolymerizing ...	54	2e-07
31	CAPG_HUMAN (P40121) Macrophage capping protein (Actin-regulatory...	50	2e-06
32	VILI_PIG (Q29261) Villin-1 (Fragment)	50	3e-06
33	FLII_DROME (Q24020) Protein flightless-1 (Flightless-I)	43	3e-04
34	SVIL_MOUSE (Q8K4L3) Supervillin (Archvillin) (p205/p250)	40	0.002
35	FLII_CAEEL (P34268) Protein flightless-1 homolog	37	0.017
36	SVIL_HUMAN (O95425) Supervillin (Archvillin) (p205/p250)	37	0.030
37	YWCC_LACLC (O86281) Hypothetical protein ywcC (ORFB)	31	1.2
38	MEP1B_HUMAN (Q16820) Meprin A beta-subunit precursor (EC 3.4.24....	31	1.6
39	MEP1B_MOUSE (Q61847) Meprin A beta-subunit precursor (EC 3.4.24....	30	2.1
40	YWCC_LACLA (O86271) Hypothetical protein ywcC	29	4.7
41	SYA_MYCGA (Q7NBY8) Alanyl-tRNA synthetase (EC 6.1.1.7) (Alanine-...	29	4.7
42	YR748_MIMIV (Q5UP04) Putative ankyrin repeat protein R748	29	4.7
43	GELS_XENLA (P14885) Gelsolin (Actin-depolymerizing factor) (ADF)...	29	4.7
44	YMJ6_YEAST (Q04489) Hypothetical 59.5 kDa protein in VPS9-RAD10 ...	29	6.2
45	LEU2_PROMP (Q7V336) 3-isopropylmalate dehydratase large subunit ...	29	6.2
46	TMM28_HUMAN (O75949) Transmembrane protein 28 (TED protein)	28	8.1
47	MUC5B_HUMAN (Q9HC84) Mucin-5B precursor (Mucin 5 subtype B, trac...	28	8.1
48	FTSW_MYCLE (Q50186) Probable cell division protein ftsW	28	8.1

>VILI2_ARATH (O81644) Villin-2|
          Length = 976

 Score =  254 bits (649), Expect = 7e-68
 Identities = 121/149 (81%), Positives = 132/149 (88%)
 Frame = +2

Query: 2   KPCIIPMEGGFASGFKTPEEETFETRLYICKGKRAIRIKQVPFARSSLNHDDVFILDTEK 181
           KPCIIP+EGG ASGFKT EEE FETRLY CKGKRAIR+KQVPFARSSLNHDDVFILDTE+
Sbjct: 113 KPCIIPLEGGVASGFKTVEEEVFETRLYTCKGKRAIRLKQVPFARSSLNHDDVFILDTEE 172

Query: 182 KIYQFNGANSNIQERAKSLEVIQHLKGKYHGGVCDVAIVDDGKLQAESDSGEFWVLFGGF 361
           KIYQFNGANSNIQERAK+LEV+Q+LK KYH G CDVAIVDDGKL  ESDSG FWVLFGGF
Sbjct: 173 KIYQFNGANSNIQERAKALEVVQYLKDKYHEGTCDVAIVDDGKLDTESDSGAFWVLFGGF 232

Query: 362 APIGKKTVSDDDVVLETTAPKLYSINGGE 448
           APIG+K  +DDD+V E+T PKLY I  G+
Sbjct: 233 APIGRKVANDDDIVPESTPPKLYCITDGK 261



 Score = 29.6 bits (65), Expect = 3.6
 Identities = 27/141 (19%), Positives = 58/141 (41%), Gaps = 11/141 (7%)
 Frame = +2

Query: 11  IIPMEGGFASGFKTPEEETFET-RLYICKGKRAIRIK----------QVPFARSSLNHDD 157
           ++ ++GG +SG+K+   E+  T   Y  +    +++           QV    +SLN  +
Sbjct: 488 MVVLKGGLSSGYKSSMGESESTDETYTPESIALVQVSGTGVHNNKAVQVETVATSLNSYE 547

Query: 158 VFILDTEKKIYQFNGANSNIQERAKSLEVIQHLKGKYHGGVCDVAIVDDGKLQAESDSGE 337
            F+L +   ++ ++G  S  ++   + +V + LK            +     +  ++S  
Sbjct: 548 CFLLQSGTSMFLWHGNQSTHEQLELATKVAEFLKPG----------ITLKHAKEGTESST 597

Query: 338 FWVLFGGFAPIGKKTVSDDDV 400
           FW   GG      K  S + +
Sbjct: 598 FWFALGGKQNFTSKKASSETI 618

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>VILI3_ARATH (O81645) Villin-3|
          Length = 966

 Score =  244 bits (623), Expect = 7e-65
 Identities = 116/149 (77%), Positives = 130/149 (87%)
 Frame = +2

Query: 2   KPCIIPMEGGFASGFKTPEEETFETRLYICKGKRAIRIKQVPFARSSLNHDDVFILDTEK 181
           KPCIIP+EGG ASGFK PEEE FETRLY CKGKRA+ +KQVPFARSSLNHDDVFILDT++
Sbjct: 115 KPCIIPLEGGVASGFKKPEEEEFETRLYTCKGKRAVHLKQVPFARSSLNHDDVFILDTKE 174

Query: 182 KIYQFNGANSNIQERAKSLEVIQHLKGKYHGGVCDVAIVDDGKLQAESDSGEFWVLFGGF 361
           KIYQFNGANSNIQERAK+L VIQ+LK K+H G  DVAIVDDGKL  ESDSGEFWVLFGGF
Sbjct: 175 KIYQFNGANSNIQERAKALVVIQYLKDKFHEGTSDVAIVDDGKLDTESDSGEFWVLFGGF 234

Query: 362 APIGKKTVSDDDVVLETTAPKLYSINGGE 448
           API +K  S+D+++ ETT PKLYSI  G+
Sbjct: 235 APIARKVASEDEIIPETTPPKLYSIADGQ 263



 Score = 32.7 bits (73), Expect = 0.43
 Identities = 33/141 (23%), Positives = 58/141 (41%), Gaps = 11/141 (7%)
 Frame = +2

Query: 11  IIPMEGGFASGFKTPEEETFET-RLYICKGKRAIRIK----------QVPFARSSLNHDD 157
           ++ ++GG +SG+K    E   +   Y  +    I++           QV    +SLN  D
Sbjct: 490 MVVLKGGLSSGYKNSMTEKGSSGETYTPESIALIQVSGTGVHNNKALQVEAVATSLNSYD 549

Query: 158 VFILDTEKKIYQFNGANSNIQERAKSLEVIQHLKGKYHGGVCDVAIVDDGKLQAESDSGE 337
            F+L +   ++ + G +S  +++  + +V + LK            +   K   ES S  
Sbjct: 550 CFLLQSGTSMFLWVGNHSTHEQQELAAKVAEFLK--------PGTTIKHAKEGTESSS-- 599

Query: 338 FWVLFGGFAPIGKKTVSDDDV 400
           FW   GG      K VS + V
Sbjct: 600 FWFALGGKQNFTSKKVSSETV 620

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>VILI4_ARATH (O65570) Villin-4|
          Length = 974

 Score =  197 bits (500), Expect = 1e-50
 Identities = 87/149 (58%), Positives = 116/149 (77%)
 Frame = +2

Query: 2   KPCIIPMEGGFASGFKTPEEETFETRLYICKGKRAIRIKQVPFARSSLNHDDVFILDTEK 181
           KPCIIP EGG ASGFK    E   TRL++C+GK  + +K+VPFARSSLNHDD++ILDT+ 
Sbjct: 115 KPCIIPQEGGVASGFKHVVAEEHITRLFVCRGKHVVHVKEVPFARSSLNHDDIYILDTKS 174

Query: 182 KIYQFNGANSNIQERAKSLEVIQHLKGKYHGGVCDVAIVDDGKLQAESDSGEFWVLFGGF 361
           KI+QFNG+NS+IQERAK+LEV+Q++K  YH G C+VA V+DGKL A++DSGEFW  FGGF
Sbjct: 175 KIFQFNGSNSSIQERAKALEVVQYIKDTYHDGTCEVATVEDGKLMADADSGEFWGFFGGF 234

Query: 362 APIGKKTVSDDDVVLETTAPKLYSINGGE 448
           AP+ +KT +D+D    +   +L+ +  G+
Sbjct: 235 APLPRKTANDEDKTYNSDITRLFCVEKGQ 263

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>VILI1_ARATH (O81643) Villin-1|
          Length = 910

 Score =  149 bits (377), Expect = 2e-36
 Identities = 72/147 (48%), Positives = 101/147 (68%), Gaps = 1/147 (0%)
 Frame = +2

Query: 2   KPCIIPMEGGFASGFKTP-EEETFETRLYICKGKRAIRIKQVPFARSSLNHDDVFILDTE 178
           KPCIIP+EG ++   KT    ET++  L  CKG   +R+K+VPF RSSLNHDDVFILDT 
Sbjct: 115 KPCIIPVEGKYSP--KTGIAGETYQVTLLRCKGDHVVRVKEVPFLRSSLNHDDVFILDTA 172

Query: 179 KKIYQFNGANSNIQERAKSLEVIQHLKGKYHGGVCDVAIVDDGKLQAESDSGEFWVLFGG 358
            K++ F G NS+ QE+AK++EV++++K   H G C+VA ++DGK   +SD+GEFW  FGG
Sbjct: 173 SKVFLFAGCNSSTQEKAKAMEVVEYIKDNKHDGRCEVATIEDGKFSGDSDAGEFWSFFGG 232

Query: 359 FAPIGKKTVSDDDVVLETTAPKLYSIN 439
           +API K + S      +T   +L+ I+
Sbjct: 233 YAPIPKLSSSTTQEQTQTPCAELFWID 259



 Score = 39.7 bits (91), Expect = 0.003
 Identities = 19/66 (28%), Positives = 39/66 (59%), Gaps = 2/66 (3%)
 Frame = +2

Query: 47  KTPEEETFETRLYICK-GKRAIRIKQV-PFARSSLNHDDVFILDTEKKIYQFNGANSNIQ 220
           K   ++  E  L+ C      +++K++  F +  L  +DVF+LD + ++Y + G+NSNI+
Sbjct: 611 KEMRKQIEEPHLFTCSCSSDVLKVKEIYNFVQDDLTTEDVFLLDCQSEVYVWIGSNSNIK 670

Query: 221 ERAKSL 238
            + ++L
Sbjct: 671 SKEEAL 676

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>GELS_DROME (Q07171) Gelsolin precursor|
          Length = 798

 Score = 73.9 bits (180), Expect = 2e-13
 Identities = 47/145 (32%), Positives = 76/145 (52%), Gaps = 6/145 (4%)
 Frame = +2

Query: 23  EGGFASGFKTPEEETF-ETRLYICKGKRAIRIKQVPFARSSLNHDDVFILDTEKKIYQFN 199
           +GG  +GFK  E     ETRL+  KGKR +R++QV  + SS+N  D FILD    IY + 
Sbjct: 174 QGGVGTGFKHVETNAQGETRLFQVKGKRNVRVRQVNLSVSSMNTGDCFILDAGSDIYVYV 233

Query: 200 GANSNIQERAKSLEVIQHLKGKYHGGVCDVAIVDDGKLQAESDSGEFWVLFGGFA--PIG 373
           G+ +   E+ K++     ++ + H G   V IVDD     ++D   F+ + G  +   + 
Sbjct: 234 GSQAKRVEKLKAISAANQIRDQDHNGRARVQIVDD--FSTDADKQHFFDVLGSGSADQVP 291

Query: 374 KKTVSDDDVVLETT---APKLYSIN 439
            ++ +D+D   E T   A  LY ++
Sbjct: 292 DESTADEDSAFERTDAAAVSLYKVS 316

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>AVIL_HUMAN (O75366) Advillin (p92)|
          Length = 819

 Score = 72.4 bits (176), Expect = 5e-13
 Identities = 47/132 (35%), Positives = 69/132 (52%), Gaps = 1/132 (0%)
 Frame = +2

Query: 2   KPCIIPMEGGFASGFKTPEEETFET-RLYICKGKRAIRIKQVPFARSSLNHDDVFILDTE 178
           K  II  +GG ASG K  E  T++  RL   KGKR IR  +V  +  S N  DVF+LD  
Sbjct: 109 KQGIIYKQGGVASGMKHVETNTYDVKRLLHVKGKRNIRATEVEMSWDSFNRGDVFLLDLG 168

Query: 179 KKIYQFNGANSNIQERAKSLEVIQHLKGKYHGGVCDVAIVDDGKLQAESDSGEFWVLFGG 358
           K I Q+NG  SN  ER K++ + + ++ +  GG  ++ +++  K  A  +  +      G
Sbjct: 169 KVIIQWNGPESNSGERLKAMLLAKDIRDRERGGRAEIGVIEGDKEAASPELMKVLQDTLG 228

Query: 359 FAPIGKKTVSDD 394
              I K TV D+
Sbjct: 229 RRSIIKPTVPDE 240



 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 37/121 (30%), Positives = 55/121 (45%), Gaps = 2/121 (1%)
 Frame = +2

Query: 11  IIPMEGGFASGFKTPEEETFETRLYICKG--KRAIRIKQVPFARSSLNHDDVFILDTEKK 184
           ++  EGG +   K   E     RL+   G  K   +  +VP   SSLN +DVF+L T+ +
Sbjct: 493 LVIFEGGTSR--KGNAEPDPPVRLFQIHGNDKSNTKAVEVPAFASSLNSNDVFLLRTQAE 550

Query: 185 IYQFNGANSNIQERAKSLEVIQHLKGKYHGGVCDVAIVDDGKLQAESDSGEFWVLFGGFA 364
            Y + G  S+  ERA + E+   L        CD +   +  +    +  EFW L GG  
Sbjct: 551 HYLWYGKGSSGDERAMAKELASLL--------CDGS---ENTVAEGQEPAEFWDLLGGKT 599

Query: 365 P 367
           P
Sbjct: 600 P 600



 Score = 33.5 bits (75), Expect = 0.25
 Identities = 20/63 (31%), Positives = 34/63 (53%), Gaps = 2/63 (3%)
 Frame = +2

Query: 125 PFARSSLNHDDVFILD-TEKKIYQFNGANSNIQERAKSL-EVIQHLKGKYHGGVCDVAIV 298
           P  +  LNHDD +ILD +  KIY + G  +   E+  ++ + +  +K K +    +V  V
Sbjct: 271 PLVQDLLNHDDCYILDQSGTKIYVWKGKGATKAEKQAAMSKALGFIKMKSYPSSTNVETV 330

Query: 299 DDG 307
           +DG
Sbjct: 331 NDG 333

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>GELS_HOMAM (Q27319) Gelsolin, cytoplasmic (Actin-depolymerizing factor) (ADF)|
          Length = 754

 Score = 70.9 bits (172), Expect = 1e-12
 Identities = 43/141 (30%), Positives = 76/141 (53%), Gaps = 1/141 (0%)
 Frame = +2

Query: 20  MEGGFASGFKTPEEET-FETRLYICKGKRAIRIKQVPFARSSLNHDDVFILDTEKKIYQF 196
           ++GG ASGF   + +  +  RL+  KG+R IRI+QV     S+N  D FILD   ++Y +
Sbjct: 113 LKGGVASGFHHVDPDAPYPARLFHVKGRRNIRIRQVEVGVGSMNKGDCFILDCGSQVYAY 172

Query: 197 NGANSNIQERAKSLEVIQHLKGKYHGGVCDVAIVDDGKLQAESDSGEFWVLFGGFAPIGK 376
            G +S   +R K+++    ++   H G   V ++D+    + S++GE     GG +P   
Sbjct: 173 MGPSSRKMDRLKAIQAANPVRADDHAGKAKVIVIDE--TASGSEAGESSPGLGGGSP--- 227

Query: 377 KTVSDDDVVLETTAPKLYSIN 439
             V+D+D  ++ +A +   +N
Sbjct: 228 DDVADEDTGVDDSAFERSEVN 248



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 39/121 (32%), Positives = 64/121 (52%), Gaps = 10/121 (8%)
 Frame = +2

Query: 26  GGFASGFKTPEE-ETFE---TRLYICKGK-----RAIRIKQVPFARSSLNHDDVFILDTE 178
           GG ASGFK   + +T++   TRL+  +G      RAI+  +V     SLN DDVF+L+T 
Sbjct: 507 GGKASGFKNVHDHDTYDVDGTRLFRVRGTCDFDTRAIQQTEVA---GSLNSDDVFVLETP 563

Query: 179 KKIYQFNGANSNIQERAKSLEVIQHLK-GKYHGGVCDVAIVDDGKLQAESDSGEFWVLFG 355
            K Y + G  ++ +E+A   +V++ +  G+      D+  V +G+     +  +FW   G
Sbjct: 564 GKTYLWIGKGASEEEKAMGEKVVELVSPGR------DMVTVAEGE-----EDDDFWGGLG 612

Query: 356 G 358
           G
Sbjct: 613 G 613



 Score = 36.6 bits (83), Expect = 0.030
 Identities = 20/62 (32%), Positives = 37/62 (59%), Gaps = 3/62 (4%)
 Frame = +2

Query: 77  RLYICKGKRA--IRIKQVP-FARSSLNHDDVFILDTEKKIYQFNGANSNIQERAKSLEVI 247
           RL+ C    A  +R+ ++  FA+  LN DDV +LD+  ++Y + G  S+ QE+ K+  + 
Sbjct: 631 RLFHCTISPAGCLRVNEMSDFAQEDLNEDDVMVLDSGDEVYVWVGQGSDDQEKEKAFTMA 690

Query: 248 QH 253
           ++
Sbjct: 691 EN 692

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>SEVE_DICDI (P10733) Severin|
          Length = 362

 Score = 70.1 bits (170), Expect = 2e-12
 Identities = 43/123 (34%), Positives = 63/123 (51%), Gaps = 3/123 (2%)
 Frame = +2

Query: 20  MEGGFASGFKTPEEETFETRLYICKGKRAIRIKQVPFARSSLNHDDVFILDTEKKIYQFN 199
           + GG  SGF   +   ++ RL    G +  ++ +VP A SSLN  D F+LD    IYQFN
Sbjct: 143 LSGGVESGFNHVKPTEYKPRLLHISGDKNAKVAEVPLATSSLNSGDCFLLDAGLTIYQFN 202

Query: 200 GANSNIQERAKSLEVIQHLKGKYHGGVCDVAIVDDGKLQAESDS---GEFWVLFGGFAPI 370
           G+ S+ QE+ K+ EV + +  +  G       +   ++  E+DS    EFW L GG   I
Sbjct: 203 GSKSSPQEKNKAAEVARAIDAERKG-------LPKVEVFCETDSDIPAEFWKLLGGKGAI 255

Query: 371 GKK 379
             K
Sbjct: 256 AAK 258



 Score = 29.6 bits (65), Expect = 3.6
 Identities = 13/31 (41%), Positives = 21/31 (67%)
 Frame = +2

Query: 134 RSSLNHDDVFILDTEKKIYQFNGANSNIQER 226
           +SSL  +DVFI+D   +IY + G+ S+  E+
Sbjct: 292 KSSLKSEDVFIIDLGNEIYTWIGSKSSPNEK 322

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>SEVE_ECHGR (Q24800) Severin|
          Length = 374

 Score = 67.4 bits (163), Expect = 2e-11
 Identities = 37/112 (33%), Positives = 64/112 (57%), Gaps = 4/112 (3%)
 Frame = +2

Query: 20  MEGGFASGFKTPEEETFETRLY-ICKGKRAIRIKQVPFARSSLNHDDVFILDTEKKIYQF 196
           ++GG+ASGF+  + + +  RL   CK  +   ++QV F++ S++  DVFILD   + YQF
Sbjct: 154 LKGGYASGFRHVKPDEYRPRLLRFCKEGKTTYMRQVAFSKQSVHSGDVFILDLGSRAYQF 213

Query: 197 NGANSNIQERAKSLEVIQHLKGKYHGGVCDVAIVDDGKLQAESDSG---EFW 343
           NG+  +  E++ +   +Q L+ K   G C+ +++D+       D G   EFW
Sbjct: 214 NGSKCSAFEKSSAAAFLQDLESK-RNGRCNTSVLDEA--DTPQDVGVLHEFW 262

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>FLII_HUMAN (Q13045) Protein flightless-1 homolog|
          Length = 1269

 Score = 67.4 bits (163), Expect = 2e-11
 Identities = 44/142 (30%), Positives = 69/142 (48%)
 Frame = +2

Query: 20   MEGGFASGFKTPEEETFETRLYICKGKRAIRIKQVPFARSSLNHDDVFILDTEKKIYQFN 199
            +EGG ASGF T E+  + TR+Y   GK+ I+++ VP   +SL+   VF+LD    IY + 
Sbjct: 601  IEGGTASGFYTVEDTHYVTRMYRVYGKKNIKLEPVPLKGTSLDPRFVFLLDRGLDIYVWR 660

Query: 200  GANSNIQERAKSLEVIQHLKGKYHGGVCDVAIVDDGKLQAESDSGEFWVLFGGFAPIGKK 379
            GA + +    K+    + +      G  ++ ++  G+     +  EFW   GG     KK
Sbjct: 661  GAQATLSSTTKARLFAEKINKNERKGKAEITLLVQGQ-----ELPEFWEALGGEPSEIKK 715

Query: 380  TVSDDDVVLETTAPKLYSINGG 445
             V +D        PKLY +  G
Sbjct: 716  HVPED---FWPPQPKLYKVGLG 734



 Score = 38.5 bits (88), Expect = 0.008
 Identities = 24/73 (32%), Positives = 38/73 (52%), Gaps = 7/73 (9%)
 Frame = +2

Query: 74   TRLYIC---KGKRAIRIKQVPFARSSLNHDDVFILDTEKKIYQFNGANSNIQERAKSLEV 244
            TRL+ C   KG  A+  K   F +  L  DD+ +LD  +++Y + G  ++  E   SL+ 
Sbjct: 1164 TRLFRCSNEKGYFAVTEKCSDFCQDDLADDDIMLLDNGQEVYMWVGTQTSQVEIKLSLKA 1223

Query: 245  ----IQHLKGKYH 271
                IQH++ K H
Sbjct: 1224 CQVYIQHMRSKEH 1236

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>AVIL_MOUSE (O88398) Advillin (p92) (Actin-binding protein DOC6)|
          Length = 819

 Score = 67.0 bits (162), Expect = 2e-11
 Identities = 38/104 (36%), Positives = 58/104 (55%), Gaps = 1/104 (0%)
 Frame = +2

Query: 2   KPCIIPMEGGFASGFKTPEEETFET-RLYICKGKRAIRIKQVPFARSSLNHDDVFILDTE 178
           K  II  +GG ASG K  E  T++  RL   KGKR I+  +V  +  S N  DVF+LD  
Sbjct: 109 KQGIIYKKGGVASGMKHVETNTYDVKRLLHVKGKRNIQATEVEMSWDSFNRGDVFLLDLG 168

Query: 179 KKIYQFNGANSNIQERAKSLEVIQHLKGKYHGGVCDVAIVDDGK 310
             I Q+NG  SN  ER K++ + + ++ +  GG  ++ +++  K
Sbjct: 169 MVIIQWNGPESNSGERLKAMLLAKDIRDRERGGRAEIGVIEGDK 212



 Score = 37.0 bits (84), Expect = 0.023
 Identities = 37/120 (30%), Positives = 56/120 (46%), Gaps = 4/120 (3%)
 Frame = +2

Query: 11  IIPMEGGFASGFKTPEEETFETRLYICKG--KRAIRIKQVPFARSSLNHDDVFILDTEKK 184
           ++  EGG +   K  EE     RL+   G  K   +  +V  + SSL  +DVF+L T+ +
Sbjct: 493 LVIYEGGTSR--KGNEEPDPPVRLFQIHGNDKSNTKAVEVSASASSLISNDVFLLRTQAE 550

Query: 185 IYQFNGANSNIQERAKSLEVIQHLKGKYHGGVCD--VAIVDDGKLQAESDSGEFWVLFGG 358
            Y + G  S+  ERA + E++  L        CD     V +G+     +  EFW L GG
Sbjct: 551 HYLWYGKGSSGDERAMAKELVDLL--------CDGNADTVAEGQ-----EPPEFWDLLGG 597



 Score = 35.0 bits (79), Expect = 0.086
 Identities = 20/63 (31%), Positives = 35/63 (55%), Gaps = 2/63 (3%)
 Frame = +2

Query: 125 PFARSSLNHDDVFILD-TEKKIYQFNGAN-SNIQERAKSLEVIQHLKGKYHGGVCDVAIV 298
           P  +  LNHDD +ILD +  KIY + G   + ++++A   + +  +K K +    +V  V
Sbjct: 271 PLVQDLLNHDDCYILDQSGTKIYVWKGKGATKVEKQAAMSKALDFIKMKGYPSSTNVETV 330

Query: 299 DDG 307
           +DG
Sbjct: 331 NDG 333

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>FLII_MOUSE (Q9JJ28) Protein flightless-1 homolog|
          Length = 1271

 Score = 66.2 bits (160), Expect = 3e-11
 Identities = 44/142 (30%), Positives = 68/142 (47%)
 Frame = +2

Query: 20   MEGGFASGFKTPEEETFETRLYICKGKRAIRIKQVPFARSSLNHDDVFILDTEKKIYQFN 199
            +EGG ASGF T E+  + TR+Y   GK+ I+++ VP   SSL+   VF+LD    IY + 
Sbjct: 601  IEGGTASGFYTVEDTHYVTRMYRVYGKKNIKLEPVPLKGSSLDPRFVFLLDQGLDIYVWR 660

Query: 200  GANSNIQERAKSLEVIQHLKGKYHGGVCDVAIVDDGKLQAESDSGEFWVLFGGFAPIGKK 379
            GA + +    K+    + +      G  ++ ++  G+     +   FW + GG     K 
Sbjct: 661  GAQATLSNTTKARLFAEKINKNERKGKAEITLLVQGQ-----EPPGFWDVLGGEPSEIKN 715

Query: 380  TVSDDDVVLETTAPKLYSINGG 445
             V DD        PKLY +  G
Sbjct: 716  HVPDD---FWPPQPKLYKVGLG 734



 Score = 37.4 bits (85), Expect = 0.017
 Identities = 24/73 (32%), Positives = 37/73 (50%), Gaps = 7/73 (9%)
 Frame = +2

Query: 74   TRLYIC---KGKRAIRIKQVPFARSSLNHDDVFILDTEKKIYQFNGANSNIQERAKSLEV 244
            TRL+ C   KG  A+  K   F +  L  DD+ +LD  +++Y + G  ++  E   SL+ 
Sbjct: 1166 TRLFRCSNEKGYFAVTEKCSDFCQDDLADDDIMLLDNGQEVYMWVGTQTSQVEIKLSLKA 1225

Query: 245  ----IQHLKGKYH 271
                IQH + K H
Sbjct: 1226 CQVYIQHTRSKEH 1238

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>VILI_MOUSE (Q62468) Villin-1|
          Length = 826

 Score = 66.2 bits (160), Expect = 3e-11
 Identities = 49/154 (31%), Positives = 74/154 (48%), Gaps = 5/154 (3%)
 Frame = +2

Query: 2   KPCIIPMEGGFASGFKTPEEETFET-RLYICKGKRAIRIKQVPFARSSLNHDDVFILDTE 178
           K  ++  +GG ASG K  E  + +  RL   KGKR +   +V  +  S N  DVF+LD  
Sbjct: 111 KQGLVIRKGGVASGMKHVETNSCDVQRLLHVKGKRNVLAGEVEMSWKSFNRGDVFLLDLG 170

Query: 179 KKIYQFNGANSNIQERAKSLEVIQHLKGKYHGGVCDVAIVDDGKLQAESDSGEFWVLFGG 358
           K I Q+NG  SN  ER + + + + ++ +  GG   V +VD  K   E DS +   +   
Sbjct: 171 KLIIQWNGPESNRMERLRGMPLAKEIRDQERGGRTYVGVVDGEK---EGDSPQLMAIMNH 227

Query: 359 -FAPIGKKTVSDDDVVLETTAP---KLYSINGGE 448
              P  +   +  D V+E  A    KLY ++  E
Sbjct: 228 VLGPRKELKAAISDSVVEPAAKAALKLYHVSDSE 261



 Score = 38.5 bits (88), Expect = 0.008
 Identities = 23/75 (30%), Positives = 41/75 (54%), Gaps = 3/75 (4%)
 Frame = +2

Query: 92  KGKRAIR-IKQVPFARSSLNHDDVFILDTEK-KIYQFNGANSNIQERAKSL-EVIQHLKG 262
           +GK  +R +   P  +  L H+D +ILD    KI+ + G N+N QER+ ++ + +  +K 
Sbjct: 261 EGKLVVREVATRPLTQDLLKHEDCYILDQGGLKIFVWKGKNANAQERSGAMSQALNFIKA 320

Query: 263 KYHGGVCDVAIVDDG 307
           K +     V + +DG
Sbjct: 321 KQYPPSTQVEVQNDG 335



 Score = 35.4 bits (80), Expect = 0.066
 Identities = 33/122 (27%), Positives = 55/122 (45%), Gaps = 3/122 (2%)
 Frame = +2

Query: 74  TRLYICKGKRAIRIK--QVPFARSSLNHDDVFILDTEKKIYQFNGANSNIQERAKSLEVI 247
           TRL+  +G  A   K  +V    +SLN +DVFIL T    Y + G   +  ER  +  V 
Sbjct: 514 TRLFQVRGTNADNTKAFEVTARATSLNSNDVFILKTPSCCYLWCGKGCSGDEREMAKMVA 573

Query: 248 QHLKGKYHGGVCDVAIVDDGKLQAESDSGEFWVLFGGFAPIGK-KTVSDDDVVLETTAPK 424
             +         +  +V +G+     +   FW+  GG AP    K + +++ V+    P+
Sbjct: 574 DTISR------TEKQVVVEGQ-----EPANFWMALGGKAPYANTKRLQEENQVI---TPR 619

Query: 425 LY 430
           L+
Sbjct: 620 LF 621



 Score = 32.3 bits (72), Expect = 0.56
 Identities = 20/80 (25%), Positives = 39/80 (48%), Gaps = 2/80 (2%)
 Frame = +2

Query: 56  EEETFETRLYICKGK--RAIRIKQVPFARSSLNHDDVFILDTEKKIYQFNGANSNIQERA 229
           E +    RL+ C  +  R +  +   F +  L  +DVF+LD   +++ + G ++N +E+ 
Sbjct: 612 ENQVITPRLFECSNQTGRFLATEIFDFNQDDLEEEDVFLLDVWDQVFFWIGKHANEEEKK 671

Query: 230 KSLEVIQHLKGKYHGGVCDV 289
            +   +Q    K H G  D+
Sbjct: 672 AAATTVQEYL-KTHPGNRDL 690

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>VILI_DICDI (P36418) Protovillin (100 kDa actin-binding protein)|
          Length = 959

 Score = 66.2 bits (160), Expect = 3e-11
 Identities = 42/124 (33%), Positives = 64/124 (51%), Gaps = 4/124 (3%)
 Frame = +2

Query: 77  RLYICKGKRAIRIKQVPFARSSLNHDDVFILDTEKKIYQFNGANSNIQERAKSLEVIQHL 256
           +L+  KG+R IR+KQV  +  SLN  DVF+LD E  IYQ+NG+ S+  E+ K L++   L
Sbjct: 194 KLFHLKGRRNIRVKQVDISSKSLNSGDVFVLDCEDFIYQWNGSESSRLEKGKGLDLTIRL 253

Query: 257 KGKYHGGVCDVAIVDDGKLQAESDSGEFWVLFGGFA-PIGKKTVSDDDVVLETTAP---K 424
           + +       + ++D+     + D  EFW   GG    + K     DD   E  +    K
Sbjct: 254 RDE-KSAKAKIIVMDEN--DTDKDHPEFWKRLGGCKDDVQKAEQGGDDFAYEKKSVEQIK 310

Query: 425 LYSI 436
           LY +
Sbjct: 311 LYQV 314



 Score = 35.0 bits (79), Expect = 0.086
 Identities = 21/67 (31%), Positives = 40/67 (59%), Gaps = 2/67 (2%)
 Frame = +2

Query: 47  KTPEEETFETRLYICKGKRAI-RIKQV-PFARSSLNHDDVFILDTEKKIYQFNGANSNIQ 220
           +T E+E  +TRL+ C     + ++ ++  F++  L+ DDV ILD +K+I+ + G  S+  
Sbjct: 693 RTVEQEK-KTRLFQCSNNSGVFKVFEIHDFSQDDLDSDDVMILDNQKQIFVWVGKESSDT 751

Query: 221 ERAKSLE 241
           E+  + E
Sbjct: 752 EKLMANE 758

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>GELS_HORSE (Q28372) Gelsolin (Actin-depolymerizing factor) (ADF) (Brevin)|
          Length = 730

 Score = 65.5 bits (158), Expect = 6e-11
 Identities = 48/147 (32%), Positives = 73/147 (49%), Gaps = 6/147 (4%)
 Frame = +2

Query: 23  EGGFASGFK--TPEEETFETRLYICKGKRAIRIKQVPFARSSLNHDDVFILDTEKKIYQF 196
           +GG ASGFK   P E   + RL   KG+R +R  +VP +  S N+ D FILD    IYQ+
Sbjct: 117 KGGVASGFKHVVPNEVVVQ-RLLQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIYQW 175

Query: 197 NGANSNIQERAKSLEVIQHLKGKYHGGVCDVAIVDDGKLQAESDSGEFWVLFGGFAPIGK 376
            G+ SN  ER K+ +V + ++     G   V++ ++G   AE ++     +     P   
Sbjct: 176 CGSKSNRFERLKATQVSKGIRDNERSGRAQVSVFEEG---AEPEA-----MLQVLGPKPT 227

Query: 377 KTVSDDDVVLETTA----PKLYSINGG 445
              + +D V E  A     KLY ++ G
Sbjct: 228 LPEATEDTVKEDAANRKLAKLYKVSNG 254



 Score = 34.3 bits (77), Expect = 0.15
 Identities = 17/41 (41%), Positives = 27/41 (65%), Gaps = 2/41 (4%)
 Frame = +2

Query: 125 PFARSSLNHDDVFILDTEK--KIYQFNGANSNIQERAKSLE 241
           PFA+ +L  +D FILD  K  KI+ + G  +N++ER  +L+
Sbjct: 268 PFAQGALRSEDCFILDHGKDGKIFVWKGKQANMEERKAALK 308



 Score = 32.7 bits (73), Expect = 0.43
 Identities = 20/67 (29%), Positives = 36/67 (53%), Gaps = 3/67 (4%)
 Frame = +2

Query: 47  KTPEEETFETRLYICKGKRA-IRIKQVP--FARSSLNHDDVFILDTEKKIYQFNGANSNI 217
           K  + +    RL+ C  K     I++VP  F +  L  DDV +LDT  +++ + G +S  
Sbjct: 606 KDKKMDAHPPRLFACSNKIGRFVIEEVPGEFMQEDLATDDVMLLDTWDQVFVWVGKDSQD 665

Query: 218 QERAKSL 238
           +E+ ++L
Sbjct: 666 EEKTEAL 672

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>GELS_CHICK (O93510) Gelsolin precursor (Actin-depolymerizing factor) (ADF)|
           (Brevin) (Homogenin)
          Length = 778

 Score = 65.1 bits (157), Expect = 8e-11
 Identities = 39/101 (38%), Positives = 56/101 (55%), Gaps = 2/101 (1%)
 Frame = +2

Query: 26  GGFASGFK--TPEEETFETRLYICKGKRAIRIKQVPFARSSLNHDDVFILDTEKKIYQFN 199
           GG ASGF+   P E T + RL   KG+R +R  +VP +  S N  D FILD    IYQ+ 
Sbjct: 166 GGVASGFRHVVPNEVTVQ-RLLQVKGRRTVRATEVPVSWESFNTGDCFILDLGSNIYQWC 224

Query: 200 GANSNIQERAKSLEVIQHLKGKYHGGVCDVAIVDDGKLQAE 322
           G+NSN QER K+  + + ++     G   V + ++G  + E
Sbjct: 225 GSNSNRQERLKATVLAKGIRDNEKNGRAKVFVSEEGAEREE 265



 Score = 35.4 bits (80), Expect = 0.066
 Identities = 17/41 (41%), Positives = 29/41 (70%), Gaps = 2/41 (4%)
 Frame = +2

Query: 125 PFARSSLNHDDVFILD--TEKKIYQFNGANSNIQERAKSLE 241
           PF++++LN +D FILD  T+ KI+ + G ++N  ER  +L+
Sbjct: 316 PFSQAALNTEDCFILDHGTDGKIFVWKGRSANSDERKAALK 356



 Score = 33.9 bits (76), Expect = 0.19
 Identities = 19/68 (27%), Positives = 37/68 (54%), Gaps = 3/68 (4%)
 Frame = +2

Query: 47  KTPEEETFETRLYICKGKRA-IRIKQVP--FARSSLNHDDVFILDTEKKIYQFNGANSNI 217
           K  + + +  RL+ C  K     I++VP    +  L  DDV ILDT  +++ + G ++  
Sbjct: 654 KDKKMDAYPPRLFACSNKSGRFTIEEVPGDLTQDDLATDDVMILDTWDQVFVWIGKDAQE 713

Query: 218 QERAKSLE 241
           +E+ ++L+
Sbjct: 714 EEKTEALK 721

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>GELS_MOUSE (P13020) Gelsolin precursor (Actin-depolymerizing factor) (ADF)|
           (Brevin)
          Length = 780

 Score = 65.1 bits (157), Expect = 8e-11
 Identities = 47/147 (31%), Positives = 69/147 (46%), Gaps = 6/147 (4%)
 Frame = +2

Query: 23  EGGFASGFK--TPEEETFETRLYICKGKRAIRIKQVPFARSSLNHDDVFILDTEKKIYQF 196
           +GG ASGFK   P E   + RL+  KG+R +R  +VP +  S N+ D FILD    IYQ+
Sbjct: 167 KGGVASGFKHVVPNEVVVQ-RLFQVKGRRVVRATEVPVSWDSFNNGDCFILDLGNNIYQW 225

Query: 197 NGANSNIQERAKSLEVIQHLKGKYHGGVCDVAIVDDGKLQAESDSGEFWVLFGGFAPIGK 376
            G+ SN  ER K+ +V + ++     G   V + ++G        GE   +     P   
Sbjct: 226 CGSGSNKFERLKATQVSKGIRDNERSGRAQVHVSEEG--------GEPEAMLQVLGPKPA 277

Query: 377 KTVSDDDVVLETTA----PKLYSINGG 445
                +D   E  A     KLY ++ G
Sbjct: 278 LPEGTEDTAKEDAANRRLAKLYKVSNG 304



 Score = 33.5 bits (75), Expect = 0.25
 Identities = 16/41 (39%), Positives = 27/41 (65%), Gaps = 2/41 (4%)
 Frame = +2

Query: 125 PFARSSLNHDDVFILD--TEKKIYQFNGANSNIQERAKSLE 241
           PFA+ +L  +D FILD   + KI+ + G  +N++ER  +L+
Sbjct: 318 PFAQGALRSEDCFILDHGRDGKIFVWKGKQANMEERKAALK 358



 Score = 29.3 bits (64), Expect = 4.7
 Identities = 18/67 (26%), Positives = 35/67 (52%), Gaps = 3/67 (4%)
 Frame = +2

Query: 47  KTPEEETFETRLYICKGKRA-IRIKQVP--FARSSLNHDDVFILDTEKKIYQFNGANSNI 217
           K  + +    RL+ C  +     I++VP    +  L  DDV +LDT  +++ + G +S  
Sbjct: 656 KDKKMDAHPPRLFACSNRIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWVGKDSQE 715

Query: 218 QERAKSL 238
           +E+ ++L
Sbjct: 716 EEKTEAL 722

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>GELS_HUMAN (P06396) Gelsolin precursor (Actin-depolymerizing factor) (ADF)|
           (Brevin) (AGEL)
          Length = 782

 Score = 65.1 bits (157), Expect = 8e-11
 Identities = 37/97 (38%), Positives = 56/97 (57%), Gaps = 2/97 (2%)
 Frame = +2

Query: 23  EGGFASGFK--TPEEETFETRLYICKGKRAIRIKQVPFARSSLNHDDVFILDTEKKIYQF 196
           +GG ASGFK   P E   + RL+  KG+R +R  +VP +  S N+ D FILD    I+Q+
Sbjct: 169 KGGVASGFKHVVPNEVVVQ-RLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQW 227

Query: 197 NGANSNIQERAKSLEVIQHLKGKYHGGVCDVAIVDDG 307
            G+NSN  ER K+ +V + ++     G   V + ++G
Sbjct: 228 CGSNSNRYERLKATQVSKGIRDNERSGRARVHVSEEG 264



 Score = 33.5 bits (75), Expect = 0.25
 Identities = 17/41 (41%), Positives = 26/41 (63%), Gaps = 2/41 (4%)
 Frame = +2

Query: 125 PFARSSLNHDDVFILDTEK--KIYQFNGANSNIQERAKSLE 241
           PFA+ +L  +D FILD  K  KI+ + G  +N +ER  +L+
Sbjct: 320 PFAQGALKSEDCFILDHGKDGKIFVWKGKQANTEERKAALK 360



 Score = 30.4 bits (67), Expect = 2.1
 Identities = 19/67 (28%), Positives = 35/67 (52%), Gaps = 3/67 (4%)
 Frame = +2

Query: 47  KTPEEETFETRLYICKGKRA-IRIKQVP--FARSSLNHDDVFILDTEKKIYQFNGANSNI 217
           K  + +    RL+ C  K     I++VP    +  L  DDV +LDT  +++ + G +S  
Sbjct: 658 KDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWVGKDSQE 717

Query: 218 QERAKSL 238
           +E+ ++L
Sbjct: 718 EEKTEAL 724

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>GELS_PIG (P20305) Gelsolin precursor (Actin-depolymerizing factor) (ADF)|
           (Brevin) (Fragment)
          Length = 772

 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 49/147 (33%), Positives = 70/147 (47%), Gaps = 6/147 (4%)
 Frame = +2

Query: 23  EGGFASGFK--TPEEETFETRLYICKGKRAIRIKQVPFARSSLNHDDVFILDTEKKIYQF 196
           +GG ASGFK   P E   + RL+  KG+R +R  +VP +  S N  D FILD    IYQ+
Sbjct: 159 KGGVASGFKHVVPNEVAVQ-RLFQVKGRRVVRATEVPVSWESFNRGDCFILDLGNDIYQW 217

Query: 197 NGANSNIQERAKSLEVIQHLKGKYHGGVCDVAIVDDGKLQAESDSGEFWVLFGGFAPIGK 376
            G+NSN  ER K+ +V + ++     G   V + ++        +G   VL     P   
Sbjct: 218 CGSNSNRYERLKATQVSKGIRDNERSGRAHVHVSEED----AEPAGMLQVL----GPKPT 269

Query: 377 KTVSDDDVVLETTA----PKLYSINGG 445
                +D V E  A     KLY ++ G
Sbjct: 270 LPEGTEDTVKEDAANRKLAKLYKVSNG 296



 Score = 33.5 bits (75), Expect = 0.25
 Identities = 17/41 (41%), Positives = 26/41 (63%), Gaps = 2/41 (4%)
 Frame = +2

Query: 125 PFARSSLNHDDVFILDTEK--KIYQFNGANSNIQERAKSLE 241
           PFA+ +L  +D FILD  K  KI+ + G  +N +ER  +L+
Sbjct: 310 PFAQGALKSEDCFILDHGKDGKIFVWKGKQANTEERKAALK 350



 Score = 30.0 bits (66), Expect = 2.8
 Identities = 18/67 (26%), Positives = 35/67 (52%), Gaps = 3/67 (4%)
 Frame = +2

Query: 47  KTPEEETFETRLYICKGKRA-IRIKQVP--FARSSLNHDDVFILDTEKKIYQFNGANSNI 217
           K  + +    RL+ C  K     +++VP    +  L  DDV +LDT  +++ + G +S  
Sbjct: 648 KDKKMDAHPPRLFACSNKIGRFVVEEVPGELMQEDLATDDVMLLDTWDQVFVWVGKDSQE 707

Query: 218 QERAKSL 238
           +E+ ++L
Sbjct: 708 EEKTEAL 714

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>VILL_HUMAN (O15195) Villin-like protein|
          Length = 856

 Score = 60.5 bits (145), Expect = 2e-09
 Identities = 35/103 (33%), Positives = 56/103 (54%), Gaps = 2/103 (1%)
 Frame = +2

Query: 2   KPCIIPMEGGFASGFKTPEEETFET-RLYICKGKRAIRIKQVPFARSSLNHDDVFILDTE 178
           +P II  +GG AS  K  E   F   RL   KG++ +   +V  + +S N  D+F+LD  
Sbjct: 110 RPGIIYRKGGLASDLKHVETNLFNIQRLLHIKGRKHVSATEVELSWNSFNKGDIFLLDLG 169

Query: 179 KKIYQFNGANSNIQERAKSLEVIQHLKGKYH-GGVCDVAIVDD 304
           K + Q+NG  ++I E+A+ L +   L+ +   GG   + +VDD
Sbjct: 170 KMMIQWNGPKTSISEKARGLALTYSLRDRERGGGRAQIGVVDD 212



 Score = 35.0 bits (79), Expect = 0.086
 Identities = 28/100 (28%), Positives = 41/100 (41%), Gaps = 2/100 (2%)
 Frame = +2

Query: 74  TRLYICKGKRA--IRIKQVPFARSSLNHDDVFILDTEKKIYQFNGANSNIQERAKSLEVI 247
           TRL+  +G  +   R  +VP   SSLN  D+F+L T    Y + G   N  +R  +  V+
Sbjct: 508 TRLFQVQGTDSHNTRTMEVPARASSLNSSDIFLLVTASVCYLWFGKGCNGDQREMARVVV 567

Query: 248 QHLKGKYHGGVCDVAIVDDGKLQAESDSGEFWVLFGGFAP 367
             +  K    V +             +   FW   GG AP
Sbjct: 568 TVISRKNEETVLE-----------GQEPPHFWEALGGRAP 596

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>VILI_HUMAN (P09327) Villin-1|
          Length = 826

 Score = 60.5 bits (145), Expect = 2e-09
 Identities = 35/101 (34%), Positives = 54/101 (53%), Gaps = 1/101 (0%)
 Frame = +2

Query: 2   KPCIIPMEGGFASGFKTPEEETFET-RLYICKGKRAIRIKQVPFARSSLNHDDVFILDTE 178
           K  ++  +GG ASG K  E  +++  RL   KGKR +   +V  +  S N  DVF+LD  
Sbjct: 111 KQGLVIRKGGVASGMKHVETNSYDVQRLLHVKGKRNVVAGEVEMSWKSFNRGDVFLLDLG 170

Query: 179 KKIYQFNGANSNIQERAKSLEVIQHLKGKYHGGVCDVAIVD 301
           K I Q+NG  S   ER + + + + ++ +  GG   V +VD
Sbjct: 171 KLIIQWNGPESTRMERLRGMTLAKEIRDQERGGRTYVGVVD 211



 Score = 37.0 bits (84), Expect = 0.023
 Identities = 32/122 (26%), Positives = 57/122 (46%), Gaps = 3/122 (2%)
 Frame = +2

Query: 74  TRLYICKGKRAIRIK--QVPFARSSLNHDDVFILDTEKKIYQFNGANSNIQERAKSLEVI 247
           TRL+  +G  A   K  +VP   + LN +DVF+L T+   Y + G   +  ER  +  V 
Sbjct: 514 TRLFQVQGTGANNTKAFEVPARANFLNSNDVFVLKTQSCCYLWCGKGCSGDEREMAKMVA 573

Query: 248 QHLKGKYHGGVCDVAIVDDGKLQAESDSGEFWVLFGGFAPIGK-KTVSDDDVVLETTAPK 424
             +         +  +V +G+     +   FW+  GG AP    K + ++++V+    P+
Sbjct: 574 DTISR------TEKQVVVEGQ-----EPANFWMALGGKAPYANTKRLQEENLVI---TPR 619

Query: 425 LY 430
           L+
Sbjct: 620 LF 621



 Score = 33.5 bits (75), Expect = 0.25
 Identities = 23/78 (29%), Positives = 39/78 (50%), Gaps = 2/78 (2%)
 Frame = +2

Query: 125 PFARSSLNHDDVFILDT-EKKIYQFNGANSNIQERAKSL-EVIQHLKGKYHGGVCDVAIV 298
           P  +  L+H+D +ILD    KIY + G  +N QE+  ++   +  +K K +     V + 
Sbjct: 273 PLTQDLLSHEDCYILDQGGLKIYVWKGKKANEQEKKGAMSHALNFIKAKQYPPSTQVEVQ 332

Query: 299 DDGKLQAESDSGEFWVLF 352
           +DG     ++S  F  LF
Sbjct: 333 NDG-----AESAVFQQLF 345



 Score = 31.6 bits (70), Expect = 0.95
 Identities = 21/76 (27%), Positives = 38/76 (50%), Gaps = 3/76 (3%)
 Frame = +2

Query: 32  FASGFKTPEEETFET-RLYICKGK--RAIRIKQVPFARSSLNHDDVFILDTEKKIYQFNG 202
           +A+  +  EE    T RL+ C  K  R +  +   F +  L  DDVF+LD   +++ + G
Sbjct: 603 YANTKRLQEENLVITPRLFECSNKTGRFLATEIPDFNQDDLEEDDVFLLDVWDQVFFWIG 662

Query: 203 ANSNIQERAKSLEVIQ 250
            ++N +E+  +    Q
Sbjct: 663 KHANEEEKKAAATTAQ 678

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>VILL_MOUSE (Q91YD6) Villin-like protein (EF-6)|
          Length = 859

 Score = 59.7 bits (143), Expect = 3e-09
 Identities = 32/100 (32%), Positives = 56/100 (56%), Gaps = 1/100 (1%)
 Frame = +2

Query: 5   PCIIPMEGGFASGFKTPEEETFET-RLYICKGKRAIRIKQVPFARSSLNHDDVFILDTEK 181
           P +I  +GG  S  K  E   +   RL   KG++ +   +V  + +S N  D+F+LD  K
Sbjct: 113 PGVIYRKGGRDSALKFAETNMYNVQRLLHIKGRKHVSATEVALSWNSFNKGDIFLLDLGK 172

Query: 182 KIYQFNGANSNIQERAKSLEVIQHLKGKYHGGVCDVAIVD 301
            + Q+NG  ++I E+A++L +  +L+ +  GG   +A+VD
Sbjct: 173 VMIQWNGPKASISEKARALTLTCNLRDRERGGRAQIAVVD 212



 Score = 31.2 bits (69), Expect = 1.2
 Identities = 29/112 (25%), Positives = 42/112 (37%), Gaps = 2/112 (1%)
 Frame = +2

Query: 38  SGFKTPEEETFETRLYICKGKRA--IRIKQVPFARSSLNHDDVFILDTEKKIYQFNGANS 211
           +G K       +TRL+  +G  +   R  +VP   SSL   DVF L T    Y + G   
Sbjct: 496 AGNKGERPPVSDTRLFHVQGTESHNTRTMEVPARASSLTSGDVFFLITSHVCYLWFGKGC 555

Query: 212 NIQERAKSLEVIQHLKGKYHGGVCDVAIVDDGKLQAESDSGEFWVLFGGFAP 367
           +  +R  +  V+    G     V +             +   FW   GG AP
Sbjct: 556 HGDQREMARTVVSVFPGNNKETVLE-----------GQEPLYFWEALGGRAP 596

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>VILI_CHICK (P02640) Villin-1|
          Length = 826

 Score = 58.5 bits (140), Expect = 7e-09
 Identities = 37/109 (33%), Positives = 59/109 (54%), Gaps = 1/109 (0%)
 Frame = +2

Query: 2   KPCIIPMEGGFASGFKTPEEETFET-RLYICKGKRAIRIKQVPFARSSLNHDDVFILDTE 178
           K  +I  +GG ASG K  E  T+   RL   KGK+ +   +V  +  S N  DVF+LD  
Sbjct: 112 KQGLIYKQGGVASGMKHVETNTYNVQRLLHVKGKKNVVAAEVEMSWKSFNLGDVFLLDLG 171

Query: 179 KKIYQFNGANSNIQERAKSLEVIQHLKGKYHGGVCDVAIVDDGKLQAES 325
           + I Q+NG  SN  ER +++ + + ++ +   G   V +V +G+ +A S
Sbjct: 172 QLIIQWNGPESNRAERLRAMTLAKDIRDRERAGRAKVGVV-EGENEAAS 219



 Score = 37.4 bits (85), Expect = 0.017
 Identities = 32/103 (31%), Positives = 43/103 (41%), Gaps = 3/103 (2%)
 Frame = +2

Query: 59  EETFETRLYICKGKRAIRIK--QVPFARSSLNHDDVFILDTEKKIYQFNGANSNIQERAK 232
           E    TRL+   G      K  +VP   +SLN +DVF+L T    Y + G   +  ER  
Sbjct: 510 EPASSTRLFHVHGTNEYNTKAFEVPVRAASLNSNDVFVLKTPSSCYLWYGKGCSGDERE- 568

Query: 233 SLEVIQHLKGKYHGGVCDVAIVDDGKLQAE-SDSGEFWVLFGG 358
                    GK    V D+    +  + AE  +  EFWV  GG
Sbjct: 569 --------MGKM---VADIISKTEKPVVAEGQEPPEFWVALGG 600



 Score = 36.2 bits (82), Expect = 0.039
 Identities = 21/75 (28%), Positives = 37/75 (49%), Gaps = 2/75 (2%)
 Frame = +2

Query: 56  EEETFETRLYICKGK--RAIRIKQVPFARSSLNHDDVFILDTEKKIYQFNGANSNIQERA 229
           E  +   RL+ C  K  R +  + V F +  L+ +DV++LDT  +I+ + G  +N  E+ 
Sbjct: 613 ENPSVPPRLFECSNKTGRFLATEIVDFTQDDLDENDVYLLDTWDQIFFWIGKGANESEKE 672

Query: 230 KSLEVIQHLKGKYHG 274
            + E  Q     + G
Sbjct: 673 AAAETAQEYLRSHPG 687



 Score = 32.7 bits (73), Expect = 0.43
 Identities = 23/78 (29%), Positives = 39/78 (50%), Gaps = 2/78 (2%)
 Frame = +2

Query: 125 PFARSSLNHDDVFILD-TEKKIYQFNGANSNIQERAKSL-EVIQHLKGKYHGGVCDVAIV 298
           P  +  L H+D +ILD    KI+ + G N+N +E+ +++   +  +K K +     V   
Sbjct: 274 PLTQDMLQHEDCYILDQAGLKIFVWKGKNANKEEKQQAMSRALGFIKAKNYLASTSVETE 333

Query: 299 DDGKLQAESDSGEFWVLF 352
           +DG     S+S  F  LF
Sbjct: 334 NDG-----SESAVFRQLF 346

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>VILD_DICDI (Q8WQ85) Villidin|
          Length = 1704

 Score = 57.8 bits (138), Expect = 1e-08
 Identities = 30/89 (33%), Positives = 51/89 (57%)
 Frame = +2

Query: 92   KGKRAIRIKQVPFARSSLNHDDVFILDTEKKIYQFNGANSNIQERAKSLEVIQHLKGKYH 271
            KGKR IR++ V  + SSLN  + FILD   +I+ + G+ ++   +AK+L+    ++ K  
Sbjct: 1033 KGKRKIRVRMVKLSTSSLNCHNSFILDAGPRIFVWAGSKTSRVNKAKALDFANRIRTKER 1092

Query: 272  GGVCDVAIVDDGKLQAESDSGEFWVLFGG 358
            GG   +  +D G+   +  S +FW + GG
Sbjct: 1093 GGKSTLIQLDQGR---DEQSFDFWEILGG 1118



 Score = 35.4 bits (80), Expect = 0.066
 Identities = 18/67 (26%), Positives = 35/67 (52%), Gaps = 2/67 (2%)
 Frame = +2

Query: 53   PEEETFETRLYICKGKRAIR--IKQVPFARSSLNHDDVFILDTEKKIYQFNGANSNIQER 226
            P   T++ R ++C     I    ++ PF++  L+   V ILD +  IY + G+ +  + +
Sbjct: 1512 PTSFTYKPRFFVCSNASGIVEVTEESPFSQDDLDIGSVCILDVQSHIYLWIGSRATHRTK 1571

Query: 227  AKSLEVI 247
              S+EV+
Sbjct: 1572 RASMEVV 1578

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>ADSV_PIG (Q29297) Adseverin (Scinderin) (Fragment)|
          Length = 125

 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 32/95 (33%), Positives = 49/95 (51%), Gaps = 1/95 (1%)
 Frame = +2

Query: 26  GGFASGFKTPEEETFET-RLYICKGKRAIRIKQVPFARSSLNHDDVFILDTEKKIYQFNG 202
           GG ASGF           RL   KG+R +R  +VP +  S N  D FI+D   +IYQ+ G
Sbjct: 31  GGVASGFNHVLTNXLSAQRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGSEIYQWFG 90

Query: 203 ANSNIQERAKSLEVIQHLKGKYHGGVCDVAIVDDG 307
           ++ N  ER K+ +V   ++     G   + +V++G
Sbjct: 91  SSCNKYERLKASQVATGIRDNERNGRSQLIVVEEG 125

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>ADSV_MOUSE (Q60604) Adseverin (Scinderin) (Gelsolin-like protein)|
          Length = 715

 Score = 56.2 bits (134), Expect = 4e-08
 Identities = 41/135 (30%), Positives = 65/135 (48%), Gaps = 1/135 (0%)
 Frame = +2

Query: 26  GGFASGFK-TPEEETFETRLYICKGKRAIRIKQVPFARSSLNHDDVFILDTEKKIYQFNG 202
           GG ASG       +    RL   KG+R +R  +VP +  S N  D FI+D   +IYQ+ G
Sbjct: 120 GGVASGLNHVLTNDLTAKRLLHVKGRRVVRATEVPLSWESFNKGDCFIIDLGTEIYQWCG 179

Query: 203 ANSNIQERAKSLEVIQHLKGKYHGGVCDVAIVDDGKLQAESDSGEFWVLFGGFAPIGKKT 382
           ++ N  ER K+ +V   ++     G   + +V++G     S+  E   + G   P     
Sbjct: 180 SSCNKYERLKASQVAIGIRDNERKGRSQLIVVEEG-----SEPSELMKVLGR-KPELPDG 233

Query: 383 VSDDDVVLETTAPKL 427
            +DDDVV + +  K+
Sbjct: 234 DNDDDVVADISNRKM 248



 Score = 33.5 bits (75), Expect = 0.25
 Identities = 21/63 (33%), Positives = 35/63 (55%), Gaps = 3/63 (4%)
 Frame = +2

Query: 62  ETFETRLYICKGKRA-IRIKQVP--FARSSLNHDDVFILDTEKKIYQFNGANSNIQERAK 232
           E    RLY C  K     I++VP  F +  L  DDV +LD  ++I+ + G ++N  E+ +
Sbjct: 610 EDHPPRLYGCSNKTGRFIIEEVPGEFTQDDLAEDDVMLLDAWEQIFIWIGKDANEVEKKE 669

Query: 233 SLE 241
           S++
Sbjct: 670 SVK 672



 Score = 30.4 bits (67), Expect = 2.1
 Identities = 16/49 (32%), Positives = 27/49 (55%), Gaps = 2/49 (4%)
 Frame = +2

Query: 125 PFARSSLNHDDVFILD--TEKKIYQFNGANSNIQERAKSLEVIQHLKGK 265
           PF+   L  ++ FILD    K+I+ + G N+N QER  +++  +    K
Sbjct: 271 PFSMGMLLSEECFILDHGAAKQIFVWKGKNANPQERKTAMKTAEEFLQK 319



 Score = 28.5 bits (62), Expect = 8.1
 Identities = 35/124 (28%), Positives = 48/124 (38%), Gaps = 5/124 (4%)
 Frame = +2

Query: 2   KPCIIPMEGGFASGFKTPEEETFETRLYICKGKRA--IRIKQVPFARSSLNHDDVFILDT 175
           KP II   G      + P   T   RL+  +   A   RI +V    +SLN +D F+L  
Sbjct: 489 KPLIIYKNGTSKKEGQAPAPPT---RLFQVRRNLASITRIVEVDVDANSLNSNDTFVLKL 545

Query: 176 EKK---IYQFNGANSNIQERAKSLEVIQHLKGKYHGGVCDVAIVDDGKLQAESDSGEFWV 346
            +    I+   GA+   QE  K  E            V DV      ++Q   +  EFW 
Sbjct: 546 PRNNGFIWIGKGAS---QEEEKGAEY-----------VADVLKCKASRIQEGKEPEEFWN 591

Query: 347 LFGG 358
             GG
Sbjct: 592 SLGG 595

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>ADSV_BOVIN (Q28046) Adseverin (Scinderin) (SC)|
          Length = 715

 Score = 56.2 bits (134), Expect = 4e-08
 Identities = 40/135 (29%), Positives = 64/135 (47%), Gaps = 1/135 (0%)
 Frame = +2

Query: 26  GGFASGFK-TPEEETFETRLYICKGKRAIRIKQVPFARSSLNHDDVFILDTEKKIYQFNG 202
           GG ASG       +    RL   KG+R +R  +VP +  S N  D FI+D   +IYQ+ G
Sbjct: 120 GGVASGLNHVLTNDLTAQRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQWCG 179

Query: 203 ANSNIQERAKSLEVIQHLKGKYHGGVCDVAIVDDGKLQAESDSGEFWVLFGGFAPIGKKT 382
           ++ N  ER K+ +V   ++     G   + +V++G     S+  E   + G   P  +  
Sbjct: 180 SSCNKYERLKASQVAIGIRDNERKGRAQLIVVEEG-----SEPSELTKVLGE-KPKLRDG 233

Query: 383 VSDDDVVLETTAPKL 427
             DDD+  + T  K+
Sbjct: 234 EDDDDIKADITNRKM 248



 Score = 35.8 bits (81), Expect = 0.050
 Identities = 22/65 (33%), Positives = 37/65 (56%), Gaps = 3/65 (4%)
 Frame = +2

Query: 56  EEETFETRLYICKGKRA-IRIKQVP--FARSSLNHDDVFILDTEKKIYQFNGANSNIQER 226
           + E    RLY C  K     I++VP  F +  L  DDV +LD  ++I+ + G ++N  E+
Sbjct: 608 QAEDHPPRLYGCSNKTGRFIIEEVPGEFTQDDLAEDDVMLLDAWEQIFIWIGKDANEVEK 667

Query: 227 AKSLE 241
           ++SL+
Sbjct: 668 SESLK 672



 Score = 31.6 bits (70), Expect = 0.95
 Identities = 26/87 (29%), Positives = 38/87 (43%), Gaps = 4/87 (4%)
 Frame = +2

Query: 110 RIKQVPFARSSLNHDDVFILDTEKKIYQFNG----ANSNIQERAKSLEVIQHLKGKYHGG 277
           RI +V    +SLN +DVF+L    K+ Q NG       + QE  K  E +  +       
Sbjct: 524 RIMEVDVDANSLNSNDVFVL----KLRQNNGYIWIGKGSTQEEEKGAEYVASVL------ 573

Query: 278 VCDVAIVDDGKLQAESDSGEFWVLFGG 358
            C  + + +GK     +  EFW   GG
Sbjct: 574 KCKTSTIQEGK-----EPEEFWNSLGG 595

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>CAPG_MOUSE (P24452) Macrophage capping protein (Myc basic motif homolog 1)|
           (Actin-capping protein GCAP39)
          Length = 352

 Score = 56.2 bits (134), Expect = 4e-08
 Identities = 43/136 (31%), Positives = 63/136 (46%), Gaps = 3/136 (2%)
 Frame = +2

Query: 23  EGGFASGF-KTPEEETFET--RLYICKGKRAIRIKQVPFARSSLNHDDVFILDTEKKIYQ 193
           EGG  S F KT          +LY  KGK+ IR  + P +  S N  D FILD  + I+ 
Sbjct: 119 EGGVESAFHKTTSGARGAAIRKLYQVKGKKNIRATERPLSWDSFNTGDCFILDLGQNIFA 178

Query: 194 FNGANSNIQERAKSLEVIQHLKGKYHGGVCDVAIVDDGKLQAESDSGEFWVLFGGFAPIG 373
           + G  SNI ER K+ ++   ++     G   V I+ DG+  AE       +   G  P  
Sbjct: 179 WCGGKSNILERNKARDLALAIRDSERQGKAQVEIITDGEEPAE------MIQVLGPKPAL 232

Query: 374 KKTVSDDDVVLETTAP 421
           K+   ++D+  + T P
Sbjct: 233 KEGNPEEDITADQTRP 248



 Score = 30.0 bits (66), Expect = 2.8
 Identities = 17/42 (40%), Positives = 24/42 (57%), Gaps = 2/42 (4%)
 Frame = +2

Query: 125 PFARSSLNHDDVFILDTE--KKIYQFNGANSNIQERAKSLEV 244
           PFA   L  DD F+LD     +IY + G  +N +ER  +L+V
Sbjct: 275 PFASELLIPDDCFVLDNGLCAQIYIWKGRKANEKERQAALQV 316

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>ADSV_HUMAN (Q9Y6U3) Adseverin (Scinderin)|
          Length = 715

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 32/100 (32%), Positives = 52/100 (52%), Gaps = 1/100 (1%)
 Frame = +2

Query: 26  GGFASGFK-TPEEETFETRLYICKGKRAIRIKQVPFARSSLNHDDVFILDTEKKIYQFNG 202
           GG ASG       +    RL   KG+R +R  +VP +  S N  D FI+D   +IYQ+ G
Sbjct: 120 GGVASGLNHVLTNDLTAKRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQWCG 179

Query: 203 ANSNIQERAKSLEVIQHLKGKYHGGVCDVAIVDDGKLQAE 322
           ++ N  ER K+ +V   ++     G  ++ +V++G   +E
Sbjct: 180 SSCNKYERLKANQVATGIRYNERKGRSELIVVEEGSEPSE 219



 Score = 34.7 bits (78), Expect = 0.11
 Identities = 21/65 (32%), Positives = 36/65 (55%), Gaps = 3/65 (4%)
 Frame = +2

Query: 56  EEETFETRLYICKGKRA-IRIKQVP--FARSSLNHDDVFILDTEKKIYQFNGANSNIQER 226
           + E    RLY C  K     I+++P  F +  L  DDV +LD  ++I+ + G ++N  E+
Sbjct: 608 QAEDHPPRLYGCSNKTGRFVIEEIPGEFTQDDLAEDDVMLLDAWEQIFIWIGKDANEVEK 667

Query: 227 AKSLE 241
            +SL+
Sbjct: 668 KESLK 672



 Score = 30.8 bits (68), Expect = 1.6
 Identities = 42/150 (28%), Positives = 61/150 (40%), Gaps = 7/150 (4%)
 Frame = +2

Query: 2   KPCIIPMEGGFASGFKTPEEETFETRLYICKGKRA--IRIKQVPFARSSLNHDDVFILD- 172
           KP II   G    G + P   T   RL+  +   A   RI +V    +SLN +DVF+L  
Sbjct: 489 KPLIIYKNGTSKKGGQAPAPPT---RLFQVRRNLASITRIVEVDVDANSLNSNDVFVLKL 545

Query: 173 TEKKIYQFNGANSNIQERAKSLEVIQHLKGKYHGGVCDVAIVDDGKLQAESDSGEFWVLF 352
            +   Y + G  ++ +E   +  V   LK       C    + +G+     +  EFW   
Sbjct: 546 PQNSGYIWVGKGASQEEEKGAEYVASVLK-------CKTLRIQEGE-----EPEEFWNSL 593

Query: 353 GGFAPIGKKTVSDDDVVLETTA----PKLY 430
           GG      K       +LET A    P+LY
Sbjct: 594 GG------KKDYQTSPLLETQAEDHPPRLY 617

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>GELS_HALRO (O61270) Gelsolin, cytoplasmic (Actin-depolymerizing factor) (ADF)|
           (Ascidian gelsolin)
          Length = 715

 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 32/92 (34%), Positives = 48/92 (52%), Gaps = 2/92 (2%)
 Frame = +2

Query: 5   PCIIPMEGGFASGFKTPEEETFETRLYIC--KGKRAIRIKQVPFARSSLNHDDVFILDTE 178
           P I  + GG ASGF   E    E R  +   KGKR +R  QVP   +SL   D ++ D  
Sbjct: 111 PTITYLIGGVASGFTHVEINEVEDRKVLTRVKGKRPVRATQVPIKWTSLTDSDSYVFDIG 170

Query: 179 KKIYQFNGANSNIQERAKSLEVIQHLKGKYHG 274
           K+IY ++G  ++  E+ K+++    LK +  G
Sbjct: 171 KEIYVWSGPKASHFEKNKAIQYADGLKNERQG 202

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>CAPG_HUMAN (P40121) Macrophage capping protein (Actin-regulatory protein|
           CAP-G)
          Length = 348

 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 35/102 (34%), Positives = 47/102 (46%), Gaps = 2/102 (1%)
 Frame = +2

Query: 23  EGGFASGFKTPEEETFET--RLYICKGKRAIRIKQVPFARSSLNHDDVFILDTEKKIYQF 196
           EGG  S F            +LY  KGK+ IR  +      S N  D FILD  + I+ +
Sbjct: 118 EGGVESAFHKTSTGAPAAIKKLYQVKGKKNIRATERALNWDSFNTGDCFILDLGQNIFAW 177

Query: 197 NGANSNIQERAKSLEVIQHLKGKYHGGVCDVAIVDDGKLQAE 322
            G  SNI ER K+ ++   ++     G   V IV DG+  AE
Sbjct: 178 CGGKSNILERNKARDLALAIRDSERQGKAQVEIVTDGEEPAE 219



 Score = 31.6 bits (70), Expect = 0.95
 Identities = 18/44 (40%), Positives = 25/44 (56%), Gaps = 2/44 (4%)
 Frame = +2

Query: 125 PFARSSLNHDDVFILDTE--KKIYQFNGANSNIQERAKSLEVIQ 250
           PFA   L  DD F+LD     KIY + G  +N +ER  +L+V +
Sbjct: 271 PFALELLISDDCFVLDNGLCGKIYIWKGRKANEKERQAALQVAE 314

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>VILI_PIG (Q29261) Villin-1 (Fragment)|
          Length = 131

 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 30/86 (34%), Positives = 45/86 (52%), Gaps = 1/86 (1%)
 Frame = +2

Query: 2   KPCIIPMEGGFASGFKTPEEETFET-RLYICKGKRAIRIKQVPFARSSLNHDDVFILDTE 178
           K  I+  +GG ASG K  E  +++  RL   KGKR +   +V  +  S N  DVF+LD  
Sbjct: 40  KQGIVIRKGGVASGMKKVETNSYDIQRLLHVKGKRNVVAXEVEMSWKSFNRGDVFLLDLG 99

Query: 179 KKIYQFNGANSNIQERAKSLEVIQHL 256
           K I Q+N   SN   R + + + + +
Sbjct: 100 KLIIQWNXPESNRMVRLRGMXLAKEI 125

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>FLII_DROME (Q24020) Protein flightless-1 (Flightless-I)|
          Length = 1256

 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 43/153 (28%), Positives = 68/153 (44%), Gaps = 8/153 (5%)
 Frame = +2

Query: 11   IIPMEGG-FASGFKTPEEETFETRLYICKGKRA-IRIKQVPFARSSLNHDDVFILDTEKK 184
            +I +EGG  A+GF T EE    TRLY+     A I ++ V  A +SL+    F+LD    
Sbjct: 596  VIYIEGGRTATGFYTIEEMIHITRLYLVHAYGATIHLEPVAPAITSLDPRHAFVLDLGTH 655

Query: 185  IYQFNGANSNIQERAKSLEVIQHLKGKYHGGVCDVAIVDDGKLQAESDSGEFWVLFG--- 355
            IY + G  S     +K+  + + +        C++ +   G+     +S EFW   G   
Sbjct: 656  IYIWMGERSKNTLNSKARLMAEKISKTERKNKCEIQLERQGE-----ESAEFWQGLGMTS 710

Query: 356  ---GFAPIGKKTVSDDDVVLETTAPKLYSINGG 445
                 A   K+ V +D    +   P+LY +  G
Sbjct: 711  EEADAAEPPKEHVPED---YQPVQPRLYQVQLG 740



 Score = 30.8 bits (68), Expect = 1.6
 Identities = 23/81 (28%), Positives = 39/81 (48%), Gaps = 7/81 (8%)
 Frame = +2

Query: 44   FKTPEEETFETRLYICKGKRA---IRIKQVPFARSSLNHDDVFILDTEKKIYQFNG---A 205
            + T  E    TRL+ C  +R    +  K   F +  L  DD+ ILD  + ++ + G   +
Sbjct: 1142 YDTDAEYMNYTRLFRCSNERGYYTVAEKCADFCQDDLADDDIMILDNGEHVFLWMGPRCS 1201

Query: 206  NSNIQERAKSLEV-IQHLKGK 265
               ++   KS +V IQH++ K
Sbjct: 1202 EVEVKLAYKSAQVYIQHMRIK 1222

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>SVIL_MOUSE (Q8K4L3) Supervillin (Archvillin) (p205/p250)|
          Length = 2170

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 29/109 (26%), Positives = 52/109 (47%), Gaps = 2/109 (1%)
 Frame = +2

Query: 92   KGKRAIRIKQVPFARSSLNHDDVFILDTEKKIYQFNGANSNIQERAKSLEVIQHLKGKYH 271
            KG+R ++ + V    SSLN  D F+L + +  + + G  SN+ E+AK+ E+   ++ K  
Sbjct: 1405 KGRRHVQTRLVEPRASSLNSGDCFLLLSPQYCFLWVGEFSNVIEKAKASELATLIQTKRE 1464

Query: 272  GG--VCDVAIVDDGKLQAESDSGEFWVLFGGFAPIGKKTVSDDDVVLET 412
             G     +  +++G       + +FW L GG           +D + ET
Sbjct: 1465 LGCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSYQSAGDPKEDELYET 1513

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>FLII_CAEEL (P34268) Protein flightless-1 homolog|
          Length = 1257

 Score = 37.4 bits (85), Expect = 0.017
 Identities = 24/72 (33%), Positives = 35/72 (48%), Gaps = 3/72 (4%)
 Frame = +2

Query: 44   FKTPEEETFETRLYIC---KGKRAIRIKQVPFARSSLNHDDVFILDTEKKIYQFNGANSN 214
            ++T       TRL+ C   KG  AI  K V F +  L+ DD+ ILD    ++ + GA S+
Sbjct: 1142 YETDSSFVKHTRLFRCTNEKGYFAISEKTVDFCQDDLDDDDIMILDNGDAVFLWIGARSS 1201

Query: 215  IQERAKSLEVIQ 250
              E   S +  Q
Sbjct: 1202 DIEAKLSYQAAQ 1213



 Score = 35.8 bits (81), Expect = 0.050
 Identities = 32/118 (27%), Positives = 51/118 (43%), Gaps = 2/118 (1%)
 Frame = +2

Query: 11  IIPMEGGFA-SGFKTPEEETFETRLYIC-KGKRAIRIKQVPFARSSLNHDDVFILDTEKK 184
           I+ +EGG   SGF T E+    TRLY       A+ ++ VP +  SL+    F+LD  + 
Sbjct: 607 IVYIEGGRTISGFYTTEKPAHLTRLYRAGVNGTAVEMEPVPLSVESLDPRFCFLLDAGET 666

Query: 185 IYQFNGANSNIQERAKSLEVIQHLKGKYHGGVCDVAIVDDGKLQAESDSGEFWVLFGG 358
           I+ ++G  S I    K+    + L  +   G  ++      +        EFW    G
Sbjct: 667 IWIWSGYKSRITVSNKARLFAERLNKRDRKGKSEIETCRQARCPP-----EFWQALTG 719

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>SVIL_HUMAN (O95425) Supervillin (Archvillin) (p205/p250)|
          Length = 2214

 Score = 36.6 bits (83), Expect = 0.030
 Identities = 24/91 (26%), Positives = 46/91 (50%), Gaps = 2/91 (2%)
 Frame = +2

Query: 92   KGKRAIRIKQVPFARSSLNHDDVFILDTEKKIYQFNGANSNIQERAKSLEVIQHLKGKYH 271
            KG+R ++ + V    S+LN  D F+L +    + + G  +N+ E+AK+ E+   ++ K  
Sbjct: 1449 KGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQTKRE 1508

Query: 272  GG--VCDVAIVDDGKLQAESDSGEFWVLFGG 358
             G     +  +++G       + +FW L GG
Sbjct: 1509 LGCRATYIQTIEEGINTHTHAAKDFWKLLGG 1539

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>YWCC_LACLC (O86281) Hypothetical protein ywcC (ORFB)|
          Length = 341

 Score = 31.2 bits (69), Expect = 1.2
 Identities = 34/138 (24%), Positives = 50/138 (36%), Gaps = 10/138 (7%)
 Frame = +2

Query: 65  TFETRLYICKGKRAIRIKQVPFARSSLNHDDVFILDTEKKIYQFNGANSNIQE------- 223
           T E  +Y   G+  + I  +  A   +    +      K  Y     NS I+        
Sbjct: 161 TDEVTVYDVIGEGKLNIVTIYRAEKGMGARHISFHPNGKIAYLVGELNSTIEVLSYNEEK 220

Query: 224 -RAKSLEVIQHLKGKYHG--GVCDVAIVDDGKLQAESDSGEFWVLFGGFAPIGKKTVSDD 394
            R   L+ I  L   YHG  GV  + I  DGK    S+ G   +     +P+G K  S  
Sbjct: 221 GRFARLQTISTLPEDYHGANGVAAIRISSDGKFLYASNRGHDSLAIYKVSPLGTKLESIG 280

Query: 395 DVVLETTAPKLYSINGGE 448
               E   P+ ++ N  E
Sbjct: 281 WTKTEYHIPRDFNFNKTE 298

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>MEP1B_HUMAN (Q16820) Meprin A beta-subunit precursor (EC 3.4.24.18)|
           (Endopeptidase-2) (N-benzoyl-L-tyrosyl-P-amino-benzoic
           acid hydrolase beta subunit) (PABA peptide hydrolase)
           (PPH beta)
          Length = 701

 Score = 30.8 bits (68), Expect = 1.6
 Identities = 22/75 (29%), Positives = 31/75 (41%)
 Frame = +2

Query: 131 ARSSLNHDDVFILDTEKKIYQFNGANSNIQERAKSLEVIQHLKGKYHGGVCDVAIVDDGK 310
           +R  +  DDV+IL T + I   N     +       ++      K + GVC V    DGK
Sbjct: 570 SRDFIKGDDVYILLTVEDISHLNSTQIQLTPAPSVQDLCSKTTCK-NDGVCTVR---DGK 625

Query: 311 LQAESDSGEFWVLFG 355
            +    SGE W   G
Sbjct: 626 AECRCQSGEDWWYMG 640

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>MEP1B_MOUSE (Q61847) Meprin A beta-subunit precursor (EC 3.4.24.18)|
           (Endopeptidase-2)
          Length = 704

 Score = 30.4 bits (67), Expect = 2.1
 Identities = 21/77 (27%), Positives = 37/77 (48%), Gaps = 2/77 (2%)
 Frame = +2

Query: 131 ARSSLNHDDVFILDTEKKIYQFNGANSNIQERAKSLEVIQHLKGKY--HGGVCDVAIVDD 304
           +R  +  DD++IL T + I   N + S + +   +L V          +GG+C   +V D
Sbjct: 571 SREFIKGDDIYILLTVEDISHLN-STSAVPDPVPTLAVHNACSEVVCQNGGIC---VVQD 626

Query: 305 GKLQAESDSGEFWVLFG 355
           G+ + +  +GE W   G
Sbjct: 627 GRAECKCPAGEDWWYMG 643

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>YWCC_LACLA (O86271) Hypothetical protein ywcC|
          Length = 341

 Score = 29.3 bits (64), Expect = 4.7
 Identities = 33/138 (23%), Positives = 50/138 (36%), Gaps = 10/138 (7%)
 Frame = +2

Query: 65  TFETRLYICKGKRAIRIKQVPFARSSLNHDDVFILDTEKKIYQFNGANSNIQE------- 223
           T E  +Y   G+  + I  +  A   +    +      K  Y     NS I+        
Sbjct: 161 TDEVTVYDVIGEGKLNIATIYRAEKGMGARHITFHPNGKIAYLVGELNSTIEVLSYNEEK 220

Query: 224 -RAKSLEVIQHLKGKYHG--GVCDVAIVDDGKLQAESDSGEFWVLFGGFAPIGKKTVSDD 394
            R   L+ I  L   YHG  GV  + I  DGK    S+ G   +     +P+G K  +  
Sbjct: 221 GRFARLQTISTLPEDYHGANGVAAIRISSDGKFLYTSNRGHDSLTTYKVSPLGTKLETIG 280

Query: 395 DVVLETTAPKLYSINGGE 448
               E   P+ ++ N  E
Sbjct: 281 WTNTEGHIPRDFNFNKTE 298

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>SYA_MYCGA (Q7NBY8) Alanyl-tRNA synthetase (EC 6.1.1.7) (Alanine--tRNA ligase)|
           (AlaRS)
          Length = 902

 Score = 29.3 bits (64), Expect = 4.7
 Identities = 15/41 (36%), Positives = 24/41 (58%)
 Frame = +2

Query: 146 NHDDVFILDTEKKIYQFNGANSNIQERAKSLEVIQHLKGKY 268
           N+D    LD  KK++ FN  NS I++  K+L   + +K +Y
Sbjct: 733 NYDLTHYLDFSKKLHSFNLPNS-IKDLRKTLRAFEQIKEEY 772

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>YR748_MIMIV (Q5UP04) Putative ankyrin repeat protein R748|
          Length = 877

 Score = 29.3 bits (64), Expect = 4.7
 Identities = 24/78 (30%), Positives = 33/78 (42%), Gaps = 6/78 (7%)
 Frame = +2

Query: 122 VPFARSSLNHDDVFILDTEKKIYQF--NGANSNIQERAKSLEVIQHLKGKYHGGVCD--- 286
           VPF + +  +    I +  K    F  N  N NI  R+K+   I HL    + G  D   
Sbjct: 74  VPFDKQNNTYLHQSIFNRHKIFVDFFMNELNDNINYRSKNKIGISHLHALVNYGYIDHIE 133

Query: 287 -VAIVDDGKLQAESDSGE 337
              I D G +Q  SD G+
Sbjct: 134 TAIIKDPGAIQQLSDDGQ 151

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>GELS_XENLA (P14885) Gelsolin (Actin-depolymerizing factor) (ADF) (Brevin)|
           (Fragment)
          Length = 417

 Score = 29.3 bits (64), Expect = 4.7
 Identities = 17/57 (29%), Positives = 31/57 (54%), Gaps = 3/57 (5%)
 Frame = +2

Query: 77  RLYICKGKRA-IRIKQVP--FARSSLNHDDVFILDTEKKIYQFNGANSNIQERAKSL 238
           RL+ C  K     I++VP   ++  L  DDV +LDT  ++Y + G  +   E+ +++
Sbjct: 303 RLFACSNKTGRFIIEEVPGEISQDDLATDDVMLLDTWDQVYVWVGNEAQEDEKKEAI 359

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>YMJ6_YEAST (Q04489) Hypothetical 59.5 kDa protein in VPS9-RAD10 intergenic|
           region
          Length = 525

 Score = 28.9 bits (63), Expect = 6.2
 Identities = 26/100 (26%), Positives = 45/100 (45%), Gaps = 12/100 (12%)
 Frame = +2

Query: 125 PFARSSLNHDDVFILDTEKKIYQ---FNGAN---------SNIQERAKSLEVIQHLKGKY 268
           PF + S+N DD + L    ++Y      G N          N++E    ++VI+ L+G+Y
Sbjct: 77  PFTKQSINVDDRYFLQFNGELYNKEISQGDNDSLYIASMLQNLKEGMGVIDVIKSLEGEY 136

Query: 269 HGGVCDVAIVDDGKLQAESDSGEFWVLFGGFAPIGKKTVS 388
              + D   V+  K            L+ G  PIG++++S
Sbjct: 137 AYTIYD---VNSSK------------LYFGRDPIGRRSLS 161

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>LEU2_PROMP (Q7V336) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)|
           (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI)
          Length = 469

 Score = 28.9 bits (63), Expect = 6.2
 Identities = 20/64 (31%), Positives = 32/64 (50%), Gaps = 6/64 (9%)
 Frame = +2

Query: 8   CIIPMEGGFASGFKTPEEETFE-TRLYICKGKRAIRIKQVPFARS-----SLNHDDVFIL 169
           C + +EGG   G+  P+E+TF   +  +C  +     K V + +S     +  +DDVF L
Sbjct: 221 CNMSIEGGARCGYINPDEKTFSYMKDKLCSPQNENWEKAVKWWKSLESSDNCVYDDVFKL 280

Query: 170 DTEK 181
           D  K
Sbjct: 281 DASK 284

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>TMM28_HUMAN (O75949) Transmembrane protein 28 (TED protein)|
          Length = 473

 Score = 28.5 bits (62), Expect = 8.1
 Identities = 15/46 (32%), Positives = 19/46 (41%), Gaps = 1/46 (2%)
 Frame = -1

Query: 350 KGPRIHQSLIPLVVSHHQRLQ-HHTRPHGTSPLNVGSLPVI*PFLG 216
           + P+ HQ        HH   Q HH  PH   P  V + P + P  G
Sbjct: 378 EAPKTHQQQFHHSYFHHYHQQYHHYHPHHDPPGRVSNKPALLPVSG 423

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>MUC5B_HUMAN (Q9HC84) Mucin-5B precursor (Mucin 5 subtype B, tracheobronchial)|
            (High molecular weight salivary mucin MG1) (Sublingual
            gland mucin)
          Length = 5703

 Score = 28.5 bits (62), Expect = 8.1
 Identities = 13/31 (41%), Positives = 19/31 (61%), Gaps = 2/31 (6%)
 Frame = -3

Query: 357  PPK--RTQNSPESDSACSFPSSTIATSHTPP 271
            PP+   T  +P + S+   PSS + T+HTPP
Sbjct: 3915 PPELTTTATTPAATSSTVTPSSALGTTHTPP 3945

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>FTSW_MYCLE (Q50186) Probable cell division protein ftsW|
          Length = 465

 Score = 28.5 bits (62), Expect = 8.1
 Identities = 13/27 (48%), Positives = 16/27 (59%)
 Frame = -1

Query: 311 VSHHQRLQHHTRPHGTSPLNVGSLPVI 231
           +SH  R    +RPH TSP+ V S  VI
Sbjct: 436 ISHSARHPLRSRPHNTSPIAVASTEVI 462


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 70,049,509
Number of Sequences: 219361
Number of extensions: 1463627
Number of successful extensions: 4673
Number of sequences better than 10.0: 48
Number of HSP's better than 10.0 without gapping: 4478
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4661
length of database: 80,573,946
effective HSP length: 102
effective length of database: 58,199,124
effective search space used: 2735358828
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

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full-length cDNA and EST

Clone Information

BLAST Search Result