>VILI2_ARATH (O81644) Villin-2|
Length = 976
Score = 237 bits (604), Expect = 1e-62
Identities = 112/159 (70%), Positives = 134/159 (84%)
Frame = +1
Query: 1 KNGSFQHDIHYWLGKDTSQDESGTAAIKTVELDVALGGRGVQYREVQGNETEKFLSYFKP 180
K G++ DIH+W+GKDTSQDE+GTAA+KTVELD LGGR VQ+RE+QG+E++KFLSYFKP
Sbjct: 55 KGGAYLFDIHFWIGKDTSQDEAGTAAVKTVELDAVLGGRAVQHREIQGHESDKFLSYFKP 114
Query: 181 CIIPEEGGVASGFRHAEINEREHVTRLFVCRGKHTVHVKEVPFARSSLNHDDIFILDTKS 360
CIIP EGGVASGF+ E E TRL+ C+GK + +K+VPFARSSLNHDD+FILDT+
Sbjct: 115 CIIPLEGGVASGFKTVE--EEVFETRLYTCKGKRAIRLKQVPFARSSLNHDDVFILDTEE 172
Query: 361 KIFQFNGSNSSIQERAKALEVVQYLXDTNHEGKCDVAAV 477
KI+QFNG+NS+IQERAKALEVVQYL D HEG CDVA V
Sbjct: 173 KIYQFNGANSNIQERAKALEVVQYLKDKYHEGTCDVAIV 211
Score = 55.1 bits (131), Expect = 9e-08
Identities = 36/144 (25%), Positives = 72/144 (50%), Gaps = 10/144 (6%)
Frame = +1
Query: 34 WLGKDTSQDESGTAAIKTVELDVALGGRGVQYREVQGNETEKFLSYFKPCIIPEEGGVAS 213
W GK + ++ TA + +L GR VQ R +G E +F++ F+P ++ + GG++S
Sbjct: 439 WFGKKSIPEDQDTAIRLANTMSNSLKGRPVQGRIYEGKEPPQFVALFQPMVVLK-GGLSS 497
Query: 214 GFRHAEINEREHVTRLFVCR----------GKHTVHVKEVPFARSSLNHDDIFILDTKSK 363
G++ + + E E + G H +V +SLN + F+L + +
Sbjct: 498 GYK-SSMGESESTDETYTPESIALVQVSGTGVHNNKAVQVETVATSLNSYECFLLQSGTS 556
Query: 364 IFQFNGSNSSIQERAKALEVVQYL 435
+F ++G+ S+ ++ A +V ++L
Sbjct: 557 MFLWHGNQSTHEQLELATKVAEFL 580
Score = 28.9 bits (63), Expect = 7.2
Identities = 18/57 (31%), Positives = 29/57 (50%)
Frame = +1
Query: 271 RGKHTVHVKEVPFARSSLNHDDIFILDTKSKIFQFNGSNSSIQERAKALEVVQYLXD 441
RGK V + FA+ L +DI+ LDT +++F + G +E+ E+ Q D
Sbjct: 630 RGKFQVE-EIYNFAQDDLLTEDIYFLDTHAEVFVWVGQCVEPKEKQTVFEIGQKYID 685
>VILI1_ARATH (O81643) Villin-1|
Length = 910
Score = 181 bits (458), Expect = 1e-45
Identities = 92/154 (59%), Positives = 112/154 (72%)
Frame = +1
Query: 16 QHDIHYWLGKDTSQDESGTAAIKTVELDVALGGRGVQYREVQGNETEKFLSYFKPCIIPE 195
Q+DIHYWLG D ++ +S A+ K ++LD ALG VQYREVQG ETEKFLSYFKPCIIP
Sbjct: 62 QYDIHYWLGIDANEVDSILASDKALDLDAALGCCTVQYREVQGQETEKFLSYFKPCIIPV 121
Query: 196 EGGVASGFRHAEINEREHVTRLFVCRGKHTVHVKEVPFARSSLNHDDIFILDTKSKIFQF 375
EG + + E VT L C+G H V VKEVPF RSSLNHDD+FILDT SK+F F
Sbjct: 122 EGKYSP--KTGIAGETYQVT-LLRCKGDHVVRVKEVPFLRSSLNHDDVFILDTASKVFLF 178
Query: 376 NGSNSSIQERAKALEVVQYLXDTNHEGKCDVAAV 477
G NSS QE+AKA+EVV+Y+ D H+G+C+VA +
Sbjct: 179 AGCNSSTQEKAKAMEVVEYIKDNKHDGRCEVATI 212
Score = 48.1 bits (113), Expect = 1e-05
Identities = 37/146 (25%), Positives = 69/146 (47%), Gaps = 8/146 (5%)
Frame = +1
Query: 4 NGSFQHDIHY------WLGKDTSQDESGTAAIKTVELDVALGGRGVQYREVQGNETEKFL 165
N S+ + + Y W+GK +S + LD + ++ +GNET+ F
Sbjct: 543 NSSYSYILQYGASAFTWIGKLSSDSDHEVLDRMLYFLDTSCQPTYIR----EGNETDTFW 598
Query: 166 SYFKPCIIPEEGGVASGFRHAEINEREHVTRLFVCR-GKHTVHVKEV-PFARSSLNHDDI 339
+ GG + + E+ ++ LF C + VKE+ F + L +D+
Sbjct: 599 NLL--------GGKSEYPKEKEMRKQIEEPHLFTCSCSSDVLKVKEIYNFVQDDLTTEDV 650
Query: 340 FILDTKSKIFQFNGSNSSIQERAKAL 417
F+LD +S+++ + GSNS+I+ + +AL
Sbjct: 651 FLLDCQSEVYVWIGSNSNIKSKEEAL 676
Score = 37.4 bits (85), Expect = 0.020
Identities = 33/153 (21%), Positives = 62/153 (40%), Gaps = 9/153 (5%)
Frame = +1
Query: 16 QHDIHYWLGKDTSQDESGTAAIKTVELDVALGGRGVQYREVQGNETEKFLSYFKPCIIPE 195
+H ++ W+G ++ Q + A + G V QGNE +F F+ ++
Sbjct: 432 EHLLYVWIGCESIQQDRADAITNASAIVGTTKGESVLCHIYQGNEPSRFFPMFQSLVV-F 490
Query: 196 EGGVASGFR---------HAEINEREHVTRLFVCRGKHTVHVKEVPFARSSLNHDDIFIL 348
+GG++ ++ E NE + V + +V +SLN +IL
Sbjct: 491 KGGLSRRYKVLLAEKEKIGEEYNENKASLFRVVGTSPRNMQAIQVNLVATSLNSSYSYIL 550
Query: 349 DTKSKIFQFNGSNSSIQERAKALEVVQYLXDTN 447
+ F + G SS + + L+ + Y DT+
Sbjct: 551 QYGASAFTWIGKLSSDSDH-EVLDRMLYFLDTS 582
>GELS_PIG (P20305) Gelsolin precursor (Actin-depolymerizing factor) (ADF)|
(Brevin) (Fragment)
Length = 772
Score = 146 bits (368), Expect = 3e-35
Identities = 78/156 (50%), Positives = 101/156 (64%)
Frame = +1
Query: 1 KNGSFQHDIHYWLGKDTSQDESGTAAIKTVELDVALGGRGVQYREVQGNETEKFLSYFKP 180
+NG+ Q+D+HYWLG + SQDESG AAI TV+LD L GR VQ+REVQG E+ FL YFK
Sbjct: 94 RNGNLQYDLHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKS 153
Query: 181 CIIPEEGGVASGFRHAEINEREHVTRLFVCRGKHTVHVKEVPFARSSLNHDDIFILDTKS 360
+ ++GGVASGF+H NE V RLF +G+ V EVP + S N D FILD +
Sbjct: 154 GLKYKKGGVASGFKHVVPNE-VAVQRLFQVKGRRVVRATEVPVSWESFNRGDCFILDLGN 212
Query: 361 KIFQFNGSNSSIQERAKALEVVQYLXDTNHEGKCDV 468
I+Q+ GSNS+ ER KA +V + + D G+ V
Sbjct: 213 DIYQWCGSNSNRYERLKATQVSKGIRDNERSGRAHV 248
Score = 68.6 bits (166), Expect = 8e-12
Identities = 55/151 (36%), Positives = 77/151 (50%), Gaps = 6/151 (3%)
Frame = +1
Query: 1 KNGSFQHDIHY-WLGKDTSQDESGTAAIKTVELDVALGGRGVQYREVQGNETEKFLSYF- 174
++G Q I Y W G ++QDE +AI T +LD LGG VQ R VQG E +S F
Sbjct: 471 RHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEPAHLMSLFG 530
Query: 175 -KPCIIPEEGGVASGFRHAEINEREHVTRLFVCRGKH---TVHVKEVPFARSSLNHDDIF 342
KP II G G + A + TRLF R T V+ +P A +LN +D F
Sbjct: 531 GKPMIIYRGGTSREGGQTAPAS-----TRLFQVRASSSGATRAVEVIPKA-GALNSNDAF 584
Query: 343 ILDTKSKIFQFNGSNSSIQERAKALEVVQYL 435
+L T S + + G+ +S E+ A E+++ L
Sbjct: 585 VLKTPSAAYLWVGTGASEAEKTGAQELLRVL 615
Score = 40.0 bits (92), Expect = 0.003
Identities = 40/146 (27%), Positives = 65/146 (44%), Gaps = 6/146 (4%)
Frame = +1
Query: 28 HYWLGKDTSQDESGTAAIKTVELDVALGGRGVQYREVQGNETEKFLSYFKPCIIPEEGGV 207
+ W+G S+ E A EL L + VQ E G+E + F GG
Sbjct: 593 YLWVGTGASEAEKTGAQ----ELLRVLRAQPVQVAE--GSEPDSFWEAL--------GGK 638
Query: 208 ASGFRHAEINERE---HVTRLFVCRGK-HTVHVKEVP--FARSSLNHDDIFILDTKSKIF 369
A+ + +++ H RLF C K V+EVP + L DD+ +LDT ++F
Sbjct: 639 AAYRTSPRLKDKKMDAHPPRLFACSNKIGRFVVEEVPGELMQEDLATDDVMLLDTWDQVF 698
Query: 370 QFNGSNSSIQERAKALEVVQYLXDTN 447
+ G +S +E+ +AL + +T+
Sbjct: 699 VWVGKDSQEEEKTEALTSAKRYIETD 724
Score = 36.6 bits (83), Expect = 0.034
Identities = 42/164 (25%), Positives = 72/164 (43%), Gaps = 11/164 (6%)
Frame = +1
Query: 19 HDIHYWLGKDTSQDE--SGTAAIKTVELDVALGGRGVQYREVQGNETEKFLSYFKPC-II 189
+DI+ W G ++++ E T K + D GR + + E L P +
Sbjct: 212 NDIYQWCGSNSNRYERLKATQVSKGIR-DNERSGRAHVHVSEEDAEPAGMLQVLGPKPTL 270
Query: 190 PEEGGVASGFRHAEINEREHVTRLF-VCRGKHTVHVK----EVPFARSSLNHDDIFILD- 351
PE G + N + + +L+ V G T+ V E PFA+ +L +D FILD
Sbjct: 271 PE--GTEDTVKEDAANRK--LAKLYKVSNGAGTMTVSLVADENPFAQGALKSEDCFILDH 326
Query: 352 -TKSKIFQFNGSNSSIQERAKALEVV-QYLXDTNHEGKCDVAAV 477
KIF + G ++ +ER AL+ ++ N+ + V+ +
Sbjct: 327 GKDGKIFVWKGKQANTEERKAALKTASDFISKMNYPKQTQVSVL 370
>GELS_HUMAN (P06396) Gelsolin precursor (Actin-depolymerizing factor) (ADF)|
(Brevin) (AGEL)
Length = 782
Score = 144 bits (364), Expect = 9e-35
Identities = 78/156 (50%), Positives = 101/156 (64%)
Frame = +1
Query: 1 KNGSFQHDIHYWLGKDTSQDESGTAAIKTVELDVALGGRGVQYREVQGNETEKFLSYFKP 180
+NG+ Q+D+HYWLG + SQDESG AAI TV+LD L GR VQ+REVQG E+ FL YFK
Sbjct: 104 RNGNLQYDLHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKS 163
Query: 181 CIIPEEGGVASGFRHAEINEREHVTRLFVCRGKHTVHVKEVPFARSSLNHDDIFILDTKS 360
+ ++GGVASGF+H NE V RLF +G+ V EVP + S N+ D FILD +
Sbjct: 164 GLKYKKGGVASGFKHVVPNE-VVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGN 222
Query: 361 KIFQFNGSNSSIQERAKALEVVQYLXDTNHEGKCDV 468
I Q+ GSNS+ ER KA +V + + D G+ V
Sbjct: 223 NIHQWCGSNSNRYERLKATQVSKGIRDNERSGRARV 258
Score = 68.2 bits (165), Expect = 1e-11
Identities = 55/151 (36%), Positives = 78/151 (51%), Gaps = 6/151 (3%)
Frame = +1
Query: 1 KNGSFQHDIHY-WLGKDTSQDESGTAAIKTVELDVALGGRGVQYREVQGNETEKFLSYF- 174
++G Q I Y W G ++QDE +AI T +LD LGG VQ R VQG E +S F
Sbjct: 481 RHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEPAHLMSLFG 540
Query: 175 -KPCIIPEEGGVASGFRHAEINEREHVTRLFVCRGKH---TVHVKEVPFARSSLNHDDIF 342
KP II + G G + A + TRLF R T V+ +P A +LN +D F
Sbjct: 541 GKPMIIYKGGTSREGGQTAPAS-----TRLFQVRANSAGATRAVEVLPKA-GALNSNDAF 594
Query: 343 ILDTKSKIFQFNGSNSSIQERAKALEVVQYL 435
+L T S + + G+ +S E+ A E+++ L
Sbjct: 595 VLKTPSAAYLWVGTGASEAEKTGAQELLRVL 625
Score = 40.8 bits (94), Expect = 0.002
Identities = 41/145 (28%), Positives = 65/145 (44%), Gaps = 11/145 (7%)
Frame = +1
Query: 19 HDIHYWLGKDTSQDE--SGTAAIKTVELDVALGGRGVQYREVQGNETEKFLSYF--KPCI 186
++IH W G ++++ E T K + D GR + +G E E L KP +
Sbjct: 222 NNIHQWCGSNSNRYERLKATQVSKGIR-DNERSGRARVHVSEEGTEPEAMLQVLGPKPAL 280
Query: 187 IPEEGGVASGFRHAEINEREHVTRLF-VCRGKHTVHVK----EVPFARSSLNHDDIFILD 351
G + N + + +L+ V G T+ V E PFA+ +L +D FILD
Sbjct: 281 ---PAGTEDTAKEDAANRK--LAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILD 335
Query: 352 --TKSKIFQFNGSNSSIQERAKALE 420
KIF + G ++ +ER AL+
Sbjct: 336 HGKDGKIFVWKGKQANTEERKAALK 360
Score = 38.9 bits (89), Expect = 0.007
Identities = 39/146 (26%), Positives = 65/146 (44%), Gaps = 6/146 (4%)
Frame = +1
Query: 28 HYWLGKDTSQDESGTAAIKTVELDVALGGRGVQYREVQGNETEKFLSYFKPCIIPEEGGV 207
+ W+G S+ E A EL L + VQ E G+E + F GG
Sbjct: 603 YLWVGTGASEAEKTGAQ----ELLRVLRAQPVQVAE--GSEPDGFWEAL--------GGK 648
Query: 208 ASGFRHAEINERE---HVTRLFVCRGK-HTVHVKEVP--FARSSLNHDDIFILDTKSKIF 369
A+ + +++ H RLF C K ++EVP + L DD+ +LDT ++F
Sbjct: 649 AAYRTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVF 708
Query: 370 QFNGSNSSIQERAKALEVVQYLXDTN 447
+ G +S +E+ +AL + +T+
Sbjct: 709 VWVGKDSQEEEKTEALTSAKRYIETD 734
>GELS_CHICK (O93510) Gelsolin precursor (Actin-depolymerizing factor) (ADF)|
(Brevin) (Homogenin)
Length = 778
Score = 142 bits (357), Expect = 6e-34
Identities = 76/156 (48%), Positives = 101/156 (64%)
Frame = +1
Query: 1 KNGSFQHDIHYWLGKDTSQDESGTAAIKTVELDVALGGRGVQYREVQGNETEKFLSYFKP 180
++G+ Q+D+H+WLG ++SQDE G AAI TV++D L G+ VQ+REVQG+E+ FL YFK
Sbjct: 100 RSGNLQYDLHFWLGDESSQDERGAAAIFTVQMDDYLQGKAVQHREVQGHESSTFLGYFKS 159
Query: 181 CIIPEEGGVASGFRHAEINEREHVTRLFVCRGKHTVHVKEVPFARSSLNHDDIFILDTKS 360
I + GGVASGFRH NE V RL +G+ TV EVP + S N D FILD S
Sbjct: 160 GIKYKAGGVASGFRHVVPNE-VTVQRLLQVKGRRTVRATEVPVSWESFNTGDCFILDLGS 218
Query: 361 KIFQFNGSNSSIQERAKALEVVQYLXDTNHEGKCDV 468
I+Q+ GSNS+ QER KA + + + D G+ V
Sbjct: 219 NIYQWCGSNSNRQERLKATVLAKGIRDNEKNGRAKV 254
Score = 67.8 bits (164), Expect = 1e-11
Identities = 50/141 (35%), Positives = 70/141 (49%), Gaps = 4/141 (2%)
Frame = +1
Query: 25 IHYWLGKDTSQDESGTAAIKTVELDVALGGRGVQYREVQGNETEKFLSYF--KPCIIPEE 198
I+ W G ++QDE T+A TV+LD LGG VQ R VQG E +S F KP I+ +
Sbjct: 486 IYTWQGAHSTQDEIATSAFLTVQLDEELGGSPVQKRVVQGKEPPHLMSMFGGKPLIVYKG 545
Query: 199 GGVASGFRHAEINEREHVTRLFVCRGKHT--VHVKEVPFARSSLNHDDIFILDTKSKIFQ 372
G G + TRLF R + E+ A S LN +D F+L T S +
Sbjct: 546 GTSREGGQTTPAQ-----TRLFQVRSSTSGATRAVELDPAASQLNSNDAFVLKTPSAAYL 600
Query: 373 FNGSNSSIQERAKALEVVQYL 435
+ G S+ E + A E+++ L
Sbjct: 601 WVGRGSNSAELSGAQELLKVL 621
Score = 43.9 bits (102), Expect = 2e-04
Identities = 40/147 (27%), Positives = 65/147 (44%), Gaps = 7/147 (4%)
Frame = +1
Query: 22 DIHYWLGKDTSQDESGTAAIKTVEL-DVALGGRGVQYREVQGNETEKFLSYFKPCIIPEE 198
+I+ W G ++++ E A + + D GR + +G E E+ L P +
Sbjct: 219 NIYQWCGSNSNRQERLKATVLAKGIRDNEKNGRAKVFVSEEGAEREEMLQVLGPKPSLPQ 278
Query: 199 GGVASGFRHAEINEREHVTRLFVCRGKHTVHVK----EVPFARSSLNHDDIFILD--TKS 360
G AS + R+ V G + V E PF++++LN +D FILD T
Sbjct: 279 G--ASDDTKTDTANRKLAKLYKVSNGAGNMAVSLVADENPFSQAALNTEDCFILDHGTDG 336
Query: 361 KIFQFNGSNSSIQERAKALEVVQYLXD 441
KIF + G +++ ER AL+ D
Sbjct: 337 KIFVWKGRSANSDERKAALKTATDFID 363
Score = 41.6 bits (96), Expect = 0.001
Identities = 39/146 (26%), Positives = 66/146 (45%), Gaps = 6/146 (4%)
Frame = +1
Query: 28 HYWLGKDTSQDESGTAAIKTVELDVALGGRGVQYREVQGNETEKFLSYFKPCIIPEEGGV 207
+ W+G+ ++ E A EL LG R VQ E G E + F GG
Sbjct: 599 YLWVGRGSNSAELSGAQ----ELLKVLGARPVQVSE--GREPDNFWVAL--------GGK 644
Query: 208 ASGFRHAEINERE---HVTRLFVCRGKH-TVHVKEVP--FARSSLNHDDIFILDTKSKIF 369
A + +++ + RLF C K ++EVP + L DD+ ILDT ++F
Sbjct: 645 APYRTSPRLKDKKMDAYPPRLFACSNKSGRFTIEEVPGDLTQDDLATDDVMILDTWDQVF 704
Query: 370 QFNGSNSSIQERAKALEVVQYLXDTN 447
+ G ++ +E+ +AL+ + +T+
Sbjct: 705 VWIGKDAQEEEKTEALKSAKRYIETD 730
>GELS_MOUSE (P13020) Gelsolin precursor (Actin-depolymerizing factor) (ADF)|
(Brevin)
Length = 780
Score = 142 bits (357), Expect = 6e-34
Identities = 76/156 (48%), Positives = 100/156 (64%)
Frame = +1
Query: 1 KNGSFQHDIHYWLGKDTSQDESGTAAIKTVELDVALGGRGVQYREVQGNETEKFLSYFKP 180
+NG+ Q+D+HYWLG + SQDESG AAI TV+LD L GR VQ+REVQG E+ F YFK
Sbjct: 102 RNGNLQYDLHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESSTFSGYFKS 161
Query: 181 CIIPEEGGVASGFRHAEINEREHVTRLFVCRGKHTVHVKEVPFARSSLNHDDIFILDTKS 360
+ ++GGVASGF+H NE V RLF +G+ V EVP + S N+ D FILD +
Sbjct: 162 GLKYKKGGVASGFKHVVPNE-VVVQRLFQVKGRRVVRATEVPVSWDSFNNGDCFILDLGN 220
Query: 361 KIFQFNGSNSSIQERAKALEVVQYLXDTNHEGKCDV 468
I+Q+ GS S+ ER KA +V + + D G+ V
Sbjct: 221 NIYQWCGSGSNKFERLKATQVSKGIRDNERSGRAQV 256
Score = 66.2 bits (160), Expect = 4e-11
Identities = 52/150 (34%), Positives = 74/150 (49%), Gaps = 5/150 (3%)
Frame = +1
Query: 1 KNGSFQHDIHY-WLGKDTSQDESGTAAIKTVELDVALGGRGVQYREVQGNETEKFLSYF- 174
++G Q I Y W G ++QDE +AI T +LD LGG VQ R VQG E +S F
Sbjct: 479 RHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEPAHLMSLFG 538
Query: 175 -KPCIIPEEGGVASGFRHAEINEREHVTRLFVCRGKHT--VHVKEVPFARSSLNHDDIFI 345
KP II + G G + A + RLF R + EV +LN +D F+
Sbjct: 539 GKPMIIYKGGTSRDGGQTAPAS-----IRLFQVRASSSGATRAVEVMPKSGALNSNDAFV 593
Query: 346 LDTKSKIFQFNGSNSSIQERAKALEVVQYL 435
L T S + + G+ +S E+ A E+++ L
Sbjct: 594 LKTPSAAYLWVGAGASEAEKTGAQELLKVL 623
Score = 40.0 bits (92), Expect = 0.003
Identities = 41/144 (28%), Positives = 66/144 (45%), Gaps = 10/144 (6%)
Frame = +1
Query: 19 HDIHYWLGKDTSQDE--SGTAAIKTVELDVALGGRGVQYREVQGNETEKFLSYFKPC-II 189
++I+ W G +++ E T K + D GR + +G E E L P +
Sbjct: 220 NNIYQWCGSGSNKFERLKATQVSKGIR-DNERSGRAQVHVSEEGGEPEAMLQVLGPKPAL 278
Query: 190 PEEGGVASGFRHAEINEREHVTRLF-VCRGKHTVHVK----EVPFARSSLNHDDIFILD- 351
PE G + N R + +L+ V G ++ V E PFA+ +L +D FILD
Sbjct: 279 PE--GTEDTAKEDAANRR--LAKLYKVSNGAGSMSVSLVADENPFAQGALRSEDCFILDH 334
Query: 352 -TKSKIFQFNGSNSSIQERAKALE 420
KIF + G ++++ER AL+
Sbjct: 335 GRDGKIFVWKGKQANMEERKAALK 358
Score = 37.4 bits (85), Expect = 0.020
Identities = 37/146 (25%), Positives = 64/146 (43%), Gaps = 6/146 (4%)
Frame = +1
Query: 28 HYWLGKDTSQDESGTAAIKTVELDVALGGRGVQYREVQGNETEKFLSYFKPCIIPEEGGV 207
+ W+G S+ E A EL L + VQ E G+E + F GG
Sbjct: 601 YLWVGAGASEAEKTGAQ----ELLKVLRSQHVQVEE--GSEPDAFWEAL--------GGK 646
Query: 208 ASGFRHAEINERE---HVTRLFVCRGK-HTVHVKEVP--FARSSLNHDDIFILDTKSKIF 369
+ + +++ H RLF C + ++EVP + L DD+ +LDT ++F
Sbjct: 647 TAYRTSPRLKDKKMDAHPPRLFACSNRIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVF 706
Query: 370 QFNGSNSSIQERAKALEVVQYLXDTN 447
+ G +S +E+ +AL + +T+
Sbjct: 707 VWVGKDSQEEEKTEALTSAKRYIETD 732
>GELS_HORSE (Q28372) Gelsolin (Actin-depolymerizing factor) (ADF) (Brevin)|
Length = 730
Score = 140 bits (354), Expect = 1e-33
Identities = 76/157 (48%), Positives = 100/157 (63%)
Frame = +1
Query: 1 KNGSFQHDIHYWLGKDTSQDESGTAAIKTVELDVALGGRGVQYREVQGNETEKFLSYFKP 180
+NG Q+D+HYWLG + SQDESG AAI TV+LD L GR VQ+REVQG E+ FL YFK
Sbjct: 52 RNGILQYDLHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKS 111
Query: 181 CIIPEEGGVASGFRHAEINEREHVTRLFVCRGKHTVHVKEVPFARSSLNHDDIFILDTKS 360
+ ++GGVASGF+H NE V RL +G+ V EVP + S N+ D FILD +
Sbjct: 112 GLKYKKGGVASGFKHVVPNE-VVVQRLLQVKGRRVVRATEVPVSWESFNNGDCFILDLGN 170
Query: 361 KIFQFNGSNSSIQERAKALEVVQYLXDTNHEGKCDVA 471
I+Q+ GS S+ ER KA +V + + D G+ V+
Sbjct: 171 NIYQWCGSKSNRFERLKATQVSKGIRDNERSGRAQVS 207
Score = 69.7 bits (169), Expect = 4e-12
Identities = 55/151 (36%), Positives = 79/151 (52%), Gaps = 6/151 (3%)
Frame = +1
Query: 1 KNGSFQHDIHY-WLGKDTSQDESGTAAIKTVELDVALGGRGVQYREVQGNETEKFLSYF- 174
++GS Q I Y W G ++QDE +AI T +LD LGG VQ R VQG E +S F
Sbjct: 429 RHGSRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEPAHLMSLFG 488
Query: 175 -KPCIIPEEGGVASGFRHAEINEREHVTRLFVCRGKH---TVHVKEVPFARSSLNHDDIF 342
KP I+ + G G + A + TRLF R T V+ +P A +LN +D F
Sbjct: 489 GKPMIVYKGGTSREGGQTAPAS-----TRLFQVRASSSGATRAVEIIPKA-GALNSNDAF 542
Query: 343 ILDTKSKIFQFNGSNSSIQERAKALEVVQYL 435
+L T S + + G+ +S E+ A E+++ L
Sbjct: 543 VLKTPSAAYLWVGAGASEAEKTGAQELLRVL 573
Score = 43.5 bits (101), Expect = 3e-04
Identities = 41/146 (28%), Positives = 66/146 (45%), Gaps = 6/146 (4%)
Frame = +1
Query: 28 HYWLGKDTSQDESGTAAIKTVELDVALGGRGVQYREVQGNETEKFLSYFKPCIIPEEGGV 207
+ W+G S+ E A EL L + VQ E G+E + F GG
Sbjct: 551 YLWVGAGASEAEKTGAQ----ELLRVLRAQPVQVAE--GSEPDSFWEAL--------GGK 596
Query: 208 ASGFRHAEINERE---HVTRLFVCRGK-HTVHVKEVP--FARSSLNHDDIFILDTKSKIF 369
A+ + +++ H RLF C K ++EVP F + L DD+ +LDT ++F
Sbjct: 597 ATYRTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGEFMQEDLATDDVMLLDTWDQVF 656
Query: 370 QFNGSNSSIQERAKALEVVQYLXDTN 447
+ G +S +E+ +AL + DT+
Sbjct: 657 VWVGKDSQDEEKTEALTSAKRYIDTD 682
Score = 34.7 bits (78), Expect = 0.13
Identities = 18/43 (41%), Positives = 27/43 (62%), Gaps = 2/43 (4%)
Frame = +1
Query: 298 EVPFARSSLNHDDIFILD--TKSKIFQFNGSNSSIQERAKALE 420
E PFA+ +L +D FILD KIF + G ++++ER AL+
Sbjct: 266 ENPFAQGALRSEDCFILDHGKDGKIFVWKGKQANMEERKAALK 308
>GELS_HOMAM (Q27319) Gelsolin, cytoplasmic (Actin-depolymerizing factor) (ADF)|
Length = 754
Score = 136 bits (342), Expect = 3e-32
Identities = 69/158 (43%), Positives = 100/158 (63%)
Frame = +1
Query: 4 NGSFQHDIHYWLGKDTSQDESGTAAIKTVELDVALGGRGVQYREVQGNETEKFLSYFKPC 183
NG+ D+H+WLG +TSQDE+GTAAIKTVELD LGG VQ+REV+G+ET FLS FK
Sbjct: 50 NGNLSWDLHFWLGSETSQDEAGTAAIKTVELDDQLGGVPVQHREVEGHETSLFLSRFKKG 109
Query: 184 IIPEEGGVASGFRHAEINEREHVTRLFVCRGKHTVHVKEVPFARSSLNHDDIFILDTKSK 363
+ +GGVASGF H + + + RLF +G+ + +++V S+N D FILD S+
Sbjct: 110 VRYLKGGVASGFHHVD-PDAPYPARLFHVKGRRNIRIRQVEVGVGSMNKGDCFILDCGSQ 168
Query: 364 IFQFNGSNSSIQERAKALEVVQYLXDTNHEGKCDVAAV 477
++ + G +S +R KA++ + +H GK V +
Sbjct: 169 VYAYMGPSSRKMDRLKAIQAANPVRADDHAGKAKVIVI 206
Score = 89.7 bits (221), Expect = 3e-18
Identities = 57/147 (38%), Positives = 86/147 (58%), Gaps = 5/147 (3%)
Frame = +1
Query: 4 NGSFQHDIHYWLGKDTSQDESGTAAIKTVELDVALGGRGVQYREVQGNETEKFLSYFKPC 183
NG+ ++ +++W G +SQDE ++AI TV LD L G+ VQ R VQG E FL FK
Sbjct: 442 NGNERYILYFWQGCASSQDEKASSAIHTVRLDNELCGKAVQVRVVQGYEPAHFLRIFKGR 501
Query: 184 IIPEEGGVASGFRHAEINEREHV--TRLFVCRGK---HTVHVKEVPFARSSLNHDDIFIL 348
++ GG ASGF++ ++ V TRLF RG T +++ A SLN DD+F+L
Sbjct: 502 MVIFLGGKASGFKNVHDHDTYDVDGTRLFRVRGTCDFDTRAIQQTEVA-GSLNSDDVFVL 560
Query: 349 DTKSKIFQFNGSNSSIQERAKALEVVQ 429
+T K + + G +S +E+A +VV+
Sbjct: 561 ETPGKTYLWIGKGASEEEKAMGEKVVE 587
Score = 39.7 bits (91), Expect = 0.004
Identities = 39/143 (27%), Positives = 62/143 (43%), Gaps = 3/143 (2%)
Frame = +1
Query: 28 HYWLGKDTSQDESGTAAIKTVELDVALGGRGVQYREVQGNETEKFLSYFKPCIIPEEGGV 207
+ W+GK S++E K VEL V+ G V E G E + F GG
Sbjct: 567 YLWIGKGASEEEKAMGE-KVVEL-VSPGRDMVTVAE--GEEDDDFWGGL--------GGK 614
Query: 208 ASGFRHAEINEREHVTRLFVCRGKHT--VHVKEVP-FARSSLNHDDIFILDTKSKIFQFN 378
+++ RLF C + V E+ FA+ LN DD+ +LD+ +++ +
Sbjct: 615 GDYQTARDLDRPLLYPRLFHCTISPAGCLRVNEMSDFAQEDLNEDDVMVLDSGDEVYVWV 674
Query: 379 GSNSSIQERAKALEVVQYLXDTN 447
G S QE+ KA + + T+
Sbjct: 675 GQGSDDQEKEKAFTMAENYIKTD 697
>GELS_DROME (Q07171) Gelsolin precursor|
Length = 798
Score = 135 bits (340), Expect = 5e-32
Identities = 72/159 (45%), Positives = 99/159 (62%)
Frame = +1
Query: 1 KNGSFQHDIHYWLGKDTSQDESGTAAIKTVELDVALGGRGVQYREVQGNETEKFLSYFKP 180
K+ D+H+WLG +TS DE+G AAI TV+LD L G VQ+REVQ +E++ FLSYFK
Sbjct: 109 KDKKLSWDVHFWLGLETSTDEAGAAAILTVQLDDLLNGGPVQHREVQDHESQLFLSYFKN 168
Query: 181 CIIPEEGGVASGFRHAEINEREHVTRLFVCRGKHTVHVKEVPFARSSLNHDDIFILDTKS 360
I E+GGV +GF+H E N + TRLF +GK V V++V + SS+N D FILD S
Sbjct: 169 GIRYEQGGVGTGFKHVETNAQGE-TRLFQVKGKRNVRVRQVNLSVSSMNTGDCFILDAGS 227
Query: 361 KIFQFNGSNSSIQERAKALEVVQYLXDTNHEGKCDVAAV 477
I+ + GS + E+ KA+ + D +H G+ V V
Sbjct: 228 DIYVYVGSQAKRVEKLKAISAANQIRDQDHNGRARVQIV 266
Score = 32.0 bits (71), Expect = 0.85
Identities = 30/105 (28%), Positives = 46/105 (43%), Gaps = 4/105 (3%)
Frame = +1
Query: 118 GVQYREVQGNETEKFLSYFKPCIIPEEGGVASGFRHAEINEREHVTRLFVCRG--KHTVH 291
G+ + QG+E F FK G + + F + +LF RG + VH
Sbjct: 537 GLLVQTNQGHEPRHFYKIFK-------GKLLTSFTALPVT-----AQLFRIRGTVESDVH 584
Query: 292 VKEVPFARSSLNHDDIFILDT--KSKIFQFNGSNSSIQERAKALE 420
EV SSL D F+L + KI+ +NG +S E+ A++
Sbjct: 585 ASEVAADSSSLASSDAFVLHSGKSHKIYIWNGLGASAFEKQAAVD 629
Score = 28.5 bits (62), Expect = 9.4
Identities = 19/62 (30%), Positives = 32/62 (51%), Gaps = 3/62 (4%)
Frame = +1
Query: 253 TRLFVCR--GKHTVHVKEVP-FARSSLNHDDIFILDTKSKIFQFNGSNSSIQERAKALEV 423
+RLF C + V+EV + + L+ DDI +LD +I+ + G S +E K L+
Sbjct: 676 SRLFHCHLSSGGFLKVEEVAQYEQEDLDSDDIMLLDAGDEIYLWVGYGVSEEENGKLLDT 735
Query: 424 VQ 429
+
Sbjct: 736 AK 737
>VILI_MOUSE (Q62468) Villin-1|
Length = 826
Score = 134 bits (337), Expect = 1e-31
Identities = 69/158 (43%), Positives = 96/158 (60%)
Frame = +1
Query: 4 NGSFQHDIHYWLGKDTSQDESGTAAIKTVELDVALGGRGVQYREVQGNETEKFLSYFKPC 183
+ + +DIHYW+G+D+SQDE G AAI T ++D L GR VQ+REVQGNE+E F SYFK
Sbjct: 54 SSTLSYDIHYWIGQDSSQDEQGAAAIYTTQMDDYLKGRAVQHREVQGNESETFRSYFKQG 113
Query: 184 IIPEEGGVASGFRHAEINEREHVTRLFVCRGKHTVHVKEVPFARSSLNHDDIFILDTKSK 363
++ +GGVASG +H E N + V RL +GK V EV + S N D+F+LD
Sbjct: 114 LVIRKGGVASGMKHVETNSCD-VQRLLHVKGKRNVLAGEVEMSWKSFNRGDVFLLDLGKL 172
Query: 364 IFQFNGSNSSIQERAKALEVVQYLXDTNHEGKCDVAAV 477
I Q+NG S+ ER + + + + + D G+ V V
Sbjct: 173 IIQWNGPESNRMERLRGMPLAKEIRDQERGGRTYVGVV 210
Score = 64.3 bits (155), Expect = 2e-10
Identities = 52/154 (33%), Positives = 69/154 (44%), Gaps = 5/154 (3%)
Frame = +1
Query: 7 GSFQHDIHY-WLGKDTSQDESGTAAIKTVELDVALGGRGVQYREVQGNETEKFLSYFKPC 183
G QH + Y W G SQDE +A + V LD VQ R G E +S FK
Sbjct: 435 GEKQHYLLYIWQGSQASQDEIAASAYQAVLLDQKYNDEPVQIRVTMGKEPPHLMSIFKGR 494
Query: 184 IIPEEGGVASGFRHAEINEREHV--TRLFVCRGKHTVHVK--EVPFARSSLNHDDIFILD 351
++ +GG + N E V TRLF RG + + K EV +SLN +D+FIL
Sbjct: 495 MVVYQGGT------SRKNNLEPVPSTRLFQVRGTNADNTKAFEVTARATSLNSNDVFILK 548
Query: 352 TKSKIFQFNGSNSSIQERAKALEVVQYLXDTNHE 453
T S + + G S ER A V + T +
Sbjct: 549 TPSCCYLWCGKGCSGDEREMAKMVADTISRTEKQ 582
Score = 35.0 bits (79), Expect = 0.10
Identities = 37/151 (24%), Positives = 59/151 (39%), Gaps = 4/151 (2%)
Frame = +1
Query: 28 HYWLGKDTSQDESGTAAIKTVELDVALGGRGVQYREVQGNETEKFLSYFKPCIIPEEGGV 207
+ W GK S DE A + + R + V+G E F GG
Sbjct: 554 YLWCGKGCSGDEREMAKMVADTIS-----RTEKQVVVEGQEPANFWMAL--------GGK 600
Query: 208 ASGFRHAEINEREHVT--RLFVCRGK--HTVHVKEVPFARSSLNHDDIFILDTKSKIFQF 375
A + E V RLF C + + + F + L +D+F+LD ++F +
Sbjct: 601 APYANTKRLQEENQVITPRLFECSNQTGRFLATEIFDFNQDDLEEEDVFLLDVWDQVFFW 660
Query: 376 NGSNSSIQERAKALEVVQYLXDTNHEGKCDV 468
G +++ +E+ A VQ T H G D+
Sbjct: 661 IGKHANEEEKKAAATTVQEYLKT-HPGNRDL 690
Score = 33.5 bits (75), Expect = 0.29
Identities = 19/46 (41%), Positives = 28/46 (60%), Gaps = 4/46 (8%)
Frame = +1
Query: 292 VKEV---PFARSSLNHDDIFILDTKS-KIFQFNGSNSSIQERAKAL 417
V+EV P + L H+D +ILD KIF + G N++ QER+ A+
Sbjct: 266 VREVATRPLTQDLLKHEDCYILDQGGLKIFVWKGKNANAQERSGAM 311
>VILI_CHICK (P02640) Villin-1|
Length = 826
Score = 132 bits (332), Expect = 5e-31
Identities = 72/160 (45%), Positives = 99/160 (61%), Gaps = 1/160 (0%)
Frame = +1
Query: 1 KNGS-FQHDIHYWLGKDTSQDESGTAAIKTVELDVALGGRGVQYREVQGNETEKFLSYFK 177
K GS F ++IHYWLGK++SQDE G AAI T ++D LG VQ+REVQG+E+E F +YFK
Sbjct: 53 KTGSGFSYNIHYWLGKNSSQDEQGAAAIYTTQMDEYLGSVAVQHREVQGHESETFRAYFK 112
Query: 178 PCIIPEEGGVASGFRHAEINEREHVTRLFVCRGKHTVHVKEVPFARSSLNHDDIFILDTK 357
+I ++GGVASG +H E N +V RL +GK V EV + S N D+F+LD
Sbjct: 113 QGLIYKQGGVASGMKHVETN-TYNVQRLLHVKGKKNVVAAEVEMSWKSFNLGDVFLLDLG 171
Query: 358 SKIFQFNGSNSSIQERAKALEVVQYLXDTNHEGKCDVAAV 477
I Q+NG S+ ER +A+ + + + D G+ V V
Sbjct: 172 QLIIQWNGPESNRAERLRAMTLAKDIRDRERAGRAKVGVV 211
Score = 62.0 bits (149), Expect = 8e-10
Identities = 44/142 (30%), Positives = 62/142 (43%), Gaps = 2/142 (1%)
Frame = +1
Query: 25 IHYWLGKDTSQDESGTAAIKTVELDVALGGRGVQYREVQGNETEKFLSYFKPCIIPEEGG 204
I+ W G+ S DE +A + V LD VQ R G E ++ FK ++ E G
Sbjct: 443 IYIWQGRHASTDELAASAYQAVFLDQKYNNEPVQVRVTMGKEPAHLMAIFKGKMVVYENG 502
Query: 205 VASGFRHAEINEREHVTRLFVCRGKHTVHVK--EVPFARSSLNHDDIFILDTKSKIFQFN 378
+ A E TRLF G + + K EVP +SLN +D+F+L T S + +
Sbjct: 503 SS----RAGGTEPASSTRLFHVHGTNEYNTKAFEVPVRAASLNSNDVFVLKTPSSCYLWY 558
Query: 379 GSNSSIQERAKALEVVQYLXDT 444
G S ER V + T
Sbjct: 559 GKGCSGDEREMGKMVADIISKT 580
Score = 36.2 bits (82), Expect = 0.045
Identities = 24/74 (32%), Positives = 39/74 (52%), Gaps = 3/74 (4%)
Frame = +1
Query: 256 RLFVCRGK--HTVHVKEVPFARSSLNHDDIFILDTKSKIFQFNGSNSSIQERAKALEVVQ 429
RLF C K + + V F + L+ +D+++LDT +IF + G ++ E+ A E Q
Sbjct: 620 RLFECSNKTGRFLATEIVDFTQDDLDENDVYLLDTWDQIFFWIGKGANESEKEAAAETAQ 679
Query: 430 -YLXDTNHEGKCDV 468
YL +H G D+
Sbjct: 680 EYL--RSHPGSRDL 691
Score = 32.0 bits (71), Expect = 0.85
Identities = 19/62 (30%), Positives = 32/62 (51%), Gaps = 8/62 (12%)
Frame = +1
Query: 304 PFARSSLNHDDIFILDTKS-KIFQFNGSNSSIQERAKA-------LEVVQYLXDTNHEGK 459
P + L H+D +ILD KIF + G N++ +E+ +A ++ YL T+ E +
Sbjct: 274 PLTQDMLQHEDCYILDQAGLKIFVWKGKNANKEEKQQAMSRALGFIKAKNYLASTSVETE 333
Query: 460 CD 465
D
Sbjct: 334 ND 335
>VILI_HUMAN (P09327) Villin-1|
Length = 826
Score = 131 bits (329), Expect = 1e-30
Identities = 68/156 (43%), Positives = 93/156 (59%)
Frame = +1
Query: 10 SFQHDIHYWLGKDTSQDESGTAAIKTVELDVALGGRGVQYREVQGNETEKFLSYFKPCII 189
S +DIHYW+G+D+S DE G AAI T ++D L GR VQ+REVQGNE+E F YFK ++
Sbjct: 56 SLSYDIHYWIGQDSSLDEQGAAAIYTTQMDDFLKGRAVQHREVQGNESEAFRGYFKQGLV 115
Query: 190 PEEGGVASGFRHAEINEREHVTRLFVCRGKHTVHVKEVPFARSSLNHDDIFILDTKSKIF 369
+GGVASG +H E N + V RL +GK V EV + S N D+F+LD I
Sbjct: 116 IRKGGVASGMKHVETNSYD-VQRLLHVKGKRNVVAGEVEMSWKSFNRGDVFLLDLGKLII 174
Query: 370 QFNGSNSSIQERAKALEVVQYLXDTNHEGKCDVAAV 477
Q+NG S+ ER + + + + + D G+ V V
Sbjct: 175 QWNGPESTRMERLRGMTLAKEIRDQERGGRTYVGVV 210
Score = 63.5 bits (153), Expect = 3e-10
Identities = 49/152 (32%), Positives = 68/152 (44%), Gaps = 3/152 (1%)
Frame = +1
Query: 7 GSFQHDIHY-WLGKDTSQDESGTAAIKTVELDVALGGRGVQYREVQGNETEKFLSYFKPC 183
G QH + Y W G SQDE +A + V LD G VQ R G E +S FK
Sbjct: 435 GEKQHYLLYVWQGSQASQDEITASAYQAVILDQKYNGEPVQIRVPMGKEPPHLMSIFKGR 494
Query: 184 IIPEEGGVASGFRHAEINEREHVTRLFVCRGKHTVHVK--EVPFARSSLNHDDIFILDTK 357
++ +GG + E TRLF +G + K EVP + LN +D+F+L T+
Sbjct: 495 MVVYQGGTS----RTNNLETGPSTRLFQVQGTGANNTKAFEVPARANFLNSNDVFVLKTQ 550
Query: 358 SKIFQFNGSNSSIQERAKALEVVQYLXDTNHE 453
S + + G S ER A V + T +
Sbjct: 551 SCCYLWCGKGCSGDEREMAKMVADTISRTEKQ 582
Score = 37.4 bits (85), Expect = 0.020
Identities = 38/148 (25%), Positives = 59/148 (39%), Gaps = 4/148 (2%)
Frame = +1
Query: 28 HYWLGKDTSQDESGTAAIKTVELDVALGGRGVQYREVQGNETEKFLSYFKPCIIPEEGGV 207
+ W GK S DE A + + R + V+G E F GG
Sbjct: 554 YLWCGKGCSGDEREMAKMVADTIS-----RTEKQVVVEGQEPANFWMAL--------GGK 600
Query: 208 ASGFRHAEINEREHVT--RLFVCRGKHTVHVK-EVP-FARSSLNHDDIFILDTKSKIFQF 375
A + E V RLF C K + E+P F + L DD+F+LD ++F +
Sbjct: 601 APYANTKRLQEENLVITPRLFECSNKTGRFLATEIPDFNQDDLEEDDVFLLDVWDQVFFW 660
Query: 376 NGSNSSIQERAKALEVVQYLXDTNHEGK 459
G +++ +E+ A Q T+ G+
Sbjct: 661 IGKHANEEEKKAAATTAQEYLKTHPSGR 688
>AVIL_HUMAN (O75366) Advillin (p92)|
Length = 819
Score = 128 bits (322), Expect = 7e-30
Identities = 66/152 (43%), Positives = 93/152 (61%)
Frame = +1
Query: 22 DIHYWLGKDTSQDESGTAAIKTVELDVALGGRGVQYREVQGNETEKFLSYFKPCIIPEEG 201
DIH+W+GKD+SQDE AAI T +LD LGG VQ+REVQ +E++ F YFK II ++G
Sbjct: 58 DIHFWIGKDSSQDEQSCAAIYTTQLDDYLGGSPVQHREVQYHESDTFRGYFKQGIIYKQG 117
Query: 202 GVASGFRHAEINEREHVTRLFVCRGKHTVHVKEVPFARSSLNHDDIFILDTKSKIFQFNG 381
GVASG +H E N + V RL +GK + EV + S N D+F+LD I Q+NG
Sbjct: 118 GVASGMKHVETNTYD-VKRLLHVKGKRNIRATEVEMSWDSFNRGDVFLLDLGKVIIQWNG 176
Query: 382 SNSSIQERAKALEVVQYLXDTNHEGKCDVAAV 477
S+ ER KA+ + + + D G+ ++ +
Sbjct: 177 PESNSGERLKAMLLAKDIRDRERGGRAEIGVI 208
Score = 77.0 bits (188), Expect = 2e-14
Identities = 51/148 (34%), Positives = 73/148 (49%), Gaps = 2/148 (1%)
Frame = +1
Query: 4 NGSFQHDIHYWLGKDTSQDESGTAAIKTVELDVALGGRGVQYREVQGNETEKFLSYFKPC 183
NG H ++ W + SQDE +A + VE+D G VQ R G E F++ FK
Sbjct: 433 NGKPHHILYIWQDRHASQDELAASAYQAVEVDRQFDGAAVQVRVRMGTEPRHFMAIFKGK 492
Query: 184 IIPEEGGVASGFRHAEINEREHVTRLFVCRGKHTVHVK--EVPFARSSLNHDDIFILDTK 357
++ EGG + E + RLF G + K EVP SSLN +D+F+L T+
Sbjct: 493 LVIFEGGTS----RKGNAEPDPPVRLFQIHGNDKSNTKAVEVPAFASSLNSNDVFLLRTQ 548
Query: 358 SKIFQFNGSNSSIQERAKALEVVQYLXD 441
++ + + G SS ERA A E+ L D
Sbjct: 549 AEHYLWYGKGSSGDERAMAKELASLLCD 576
Score = 30.0 bits (66), Expect = 3.2
Identities = 14/39 (35%), Positives = 24/39 (61%), Gaps = 1/39 (2%)
Frame = +1
Query: 304 PFARSSLNHDDIFILD-TKSKIFQFNGSNSSIQERAKAL 417
P + LNHDD +ILD + +KI+ + G ++ E+ A+
Sbjct: 271 PLVQDLLNHDDCYILDQSGTKIYVWKGKGATKAEKQAAM 309
>AVIL_MOUSE (O88398) Advillin (p92) (Actin-binding protein DOC6)|
Length = 819
Score = 125 bits (315), Expect = 4e-29
Identities = 65/152 (42%), Positives = 93/152 (61%)
Frame = +1
Query: 22 DIHYWLGKDTSQDESGTAAIKTVELDVALGGRGVQYREVQGNETEKFLSYFKPCIIPEEG 201
+IH+W+GKD+SQDE AAI T +LD LGG VQ+REVQ +E++ F YFK II ++G
Sbjct: 58 NIHFWIGKDSSQDEQSCAAIYTTQLDDYLGGSPVQHREVQYHESDTFRGYFKQGIIYKKG 117
Query: 202 GVASGFRHAEINEREHVTRLFVCRGKHTVHVKEVPFARSSLNHDDIFILDTKSKIFQFNG 381
GVASG +H E N + V RL +GK + EV + S N D+F+LD I Q+NG
Sbjct: 118 GVASGMKHVETNTYD-VKRLLHVKGKRNIQATEVEMSWDSFNRGDVFLLDLGMVIIQWNG 176
Query: 382 SNSSIQERAKALEVVQYLXDTNHEGKCDVAAV 477
S+ ER KA+ + + + D G+ ++ +
Sbjct: 177 PESNSGERLKAMLLAKDIRDRERGGRAEIGVI 208
Score = 72.0 bits (175), Expect = 7e-13
Identities = 49/150 (32%), Positives = 74/150 (49%), Gaps = 2/150 (1%)
Frame = +1
Query: 4 NGSFQHDIHYWLGKDTSQDESGTAAIKTVELDVALGGRGVQYREVQGNETEKFLSYFKPC 183
NG + ++ W G+ S+DE +A + VE+D VQ R G E F++ FK
Sbjct: 433 NGKPHYILYIWQGRHASRDELAASAYRAVEVDQQFDRAPVQVRVSMGKEPRHFMAIFKGK 492
Query: 184 IIPEEGGVASGFRHAEINEREHVTRLFVCRGKHTVHVK--EVPFARSSLNHDDIFILDTK 357
++ EGG + E + RLF G + K EV + SSL +D+F+L T+
Sbjct: 493 LVIYEGGTS----RKGNEEPDPPVRLFQIHGNDKSNTKAVEVSASASSLISNDVFLLRTQ 548
Query: 358 SKIFQFNGSNSSIQERAKALEVVQYLXDTN 447
++ + + G SS ERA A E+V L D N
Sbjct: 549 AEHYLWYGKGSSGDERAMAKELVDLLCDGN 578
Score = 30.8 bits (68), Expect = 1.9
Identities = 20/58 (34%), Positives = 33/58 (56%), Gaps = 8/58 (13%)
Frame = +1
Query: 304 PFARSSLNHDDIFILD-TKSKIFQFNGSNSSIQER----AKALEVVQ---YLXDTNHE 453
P + LNHDD +ILD + +KI+ + G ++ E+ +KAL+ ++ Y TN E
Sbjct: 271 PLVQDLLNHDDCYILDQSGTKIYVWKGKGATKVEKQAAMSKALDFIKMKGYPSSTNVE 328
>ADSV_MOUSE (Q60604) Adseverin (Scinderin) (Gelsolin-like protein)|
Length = 715
Score = 117 bits (294), Expect = 1e-26
Identities = 64/155 (41%), Positives = 92/155 (59%)
Frame = +1
Query: 13 FQHDIHYWLGKDTSQDESGTAAIKTVELDVALGGRGVQYREVQGNETEKFLSYFKPCIIP 192
F + +H+WLGK+ SQDES AAI TV++D LGG+ VQ RE+QG E+ F+ YFK +
Sbjct: 58 FSYRLHFWLGKECSQDESTAAAIFTVQMDDYLGGKPVQSRELQGYESTDFVGYFKGGLKY 117
Query: 193 EEGGVASGFRHAEINEREHVTRLFVCRGKHTVHVKEVPFARSSLNHDDIFILDTKSKIFQ 372
+ GGVASG H N+ RL +G+ V EVP + S N D FI+D ++I+Q
Sbjct: 118 KAGGVASGLNHVLTNDLT-AKRLLHVKGRRVVRATEVPLSWESFNKGDCFIIDLGTEIYQ 176
Query: 373 FNGSNSSIQERAKALEVVQYLXDTNHEGKCDVAAV 477
+ GS+ + ER KA +V + D +G+ + V
Sbjct: 177 WCGSSCNKYERLKASQVAIGIRDNERKGRSQLIVV 211
Score = 55.8 bits (133), Expect = 5e-08
Identities = 49/139 (35%), Positives = 66/139 (47%), Gaps = 5/139 (3%)
Frame = +1
Query: 25 IHYWLGKDTSQDESGTAAIKTVELDVALGGRGVQYREVQGNETEKFLSYF--KPCIIPEE 198
I+ W G + ++DE +A TV+LD +LGG+ VQ R QG E LS F KP II
Sbjct: 437 IYTWQGANATRDELTMSAFLTVQLDRSLGGQAVQVRVSQGKEPAHLLSLFKDKPLII--- 493
Query: 199 GGVASGFRHAEINEREHVTRLFVCRGK--HTVHVKEVPFARSSLNHDDIFILD-TKSKIF 369
+G E TRLF R + EV +SLN +D F+L ++ F
Sbjct: 494 --YKNGTSKKEGQAPAPPTRLFQVRRNLASITRIVEVDVDANSLNSNDTFVLKLPRNNGF 551
Query: 370 QFNGSNSSIQERAKALEVV 426
+ G +S QE K E V
Sbjct: 552 IWIGKGAS-QEEEKGAEYV 569
Score = 38.1 bits (87), Expect = 0.012
Identities = 35/148 (23%), Positives = 65/148 (43%), Gaps = 6/148 (4%)
Frame = +1
Query: 34 WLGKDTSQDESGTAAIKTVELDVALGGRGVQYREVQGNETEKFLSYFKPCIIPEEGGVAS 213
W+GK SQ+E A L R +G E E+F + G
Sbjct: 553 WIGKGASQEEEKGAEYVADVLKCKAS------RIQEGKEPEEFWNSL---------GGRG 597
Query: 214 GFRHAEINE---REHVTRLFVCRGKH-TVHVKEVP--FARSSLNHDDIFILDTKSKIFQF 375
++ + + E +H RL+ C K ++EVP F + L DD+ +LD +IF +
Sbjct: 598 DYQTSPLLETRAEDHPPRLYGCSNKTGRFIIEEVPGEFTQDDLAEDDVMLLDAWEQIFIW 657
Query: 376 NGSNSSIQERAKALEVVQYLXDTNHEGK 459
G +++ E+ ++++ + +T+ G+
Sbjct: 658 IGKDANEVEKKESVKSAKMYLETDPSGR 685
Score = 32.3 bits (72), Expect = 0.65
Identities = 18/53 (33%), Positives = 30/53 (56%), Gaps = 2/53 (3%)
Frame = +1
Query: 277 KHTVHVKEVPFARSSLNHDDIFILD--TKSKIFQFNGSNSSIQERAKALEVVQ 429
K T+ +E PF+ L ++ FILD +IF + G N++ QER A++ +
Sbjct: 262 KVTLVAEENPFSMGMLLSEECFILDHGAAKQIFVWKGKNANPQERKTAMKTAE 314
>ADSV_HUMAN (Q9Y6U3) Adseverin (Scinderin)|
Length = 715
Score = 117 bits (293), Expect = 2e-26
Identities = 64/155 (41%), Positives = 93/155 (60%)
Frame = +1
Query: 13 FQHDIHYWLGKDTSQDESGTAAIKTVELDVALGGRGVQYREVQGNETEKFLSYFKPCIIP 192
F + +H+WLGK+ SQDES AAI TV++D LGG+ VQ RE+QG E+ F+SYFK +
Sbjct: 58 FTYHLHFWLGKECSQDESTAAAIFTVQMDDYLGGKPVQNRELQGYESNDFVSYFKGGLKY 117
Query: 193 EEGGVASGFRHAEINEREHVTRLFVCRGKHTVHVKEVPFARSSLNHDDIFILDTKSKIFQ 372
+ GGVASG H N+ RL +G+ V EVP + S N D FI+D ++I+Q
Sbjct: 118 KAGGVASGLNHVLTNDLT-AKRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQ 176
Query: 373 FNGSNSSIQERAKALEVVQYLXDTNHEGKCDVAAV 477
+ GS+ + ER KA +V + +G+ ++ V
Sbjct: 177 WCGSSCNKYERLKANQVATGIRYNERKGRSELIVV 211
Score = 59.3 bits (142), Expect = 5e-09
Identities = 47/138 (34%), Positives = 63/138 (45%), Gaps = 4/138 (2%)
Frame = +1
Query: 25 IHYWLGKDTSQDESGTAAIKTVELDVALGGRGVQYREVQGNETEKFLSYF--KPCIIPEE 198
I+ W G + ++DE T+A TV+LD +LGG+ VQ R QG E LS F KP II +
Sbjct: 437 IYTWQGANATRDELTTSAFLTVQLDRSLGGQAVQIRVSQGKEPVHLLSLFKDKPLIIYKN 496
Query: 199 GGVASGFRHAEINEREHVTRLFVCRGK--HTVHVKEVPFARSSLNHDDIFILDTKSKIFQ 372
G G + TRLF R + EV +SLN +D+F+L
Sbjct: 497 GTSKKGGQ-----APAPPTRLFQVRRNLASITRIVEVDVDANSLNSNDVFVLKLPQNSGY 551
Query: 373 FNGSNSSIQERAKALEVV 426
+ QE K E V
Sbjct: 552 IWVGKGASQEEEKGAEYV 569
Score = 40.0 bits (92), Expect = 0.003
Identities = 38/154 (24%), Positives = 70/154 (45%), Gaps = 6/154 (3%)
Frame = +1
Query: 16 QHDIHYWLGKDTSQDESGTAAIKTVELDVALGGRGVQYREVQGNETEKFLSYFKPCIIPE 195
Q+ + W+GK SQ+E A VA + R +G E E+F +
Sbjct: 547 QNSGYIWVGKGASQEEEKGAEY------VASVLKCKTLRIQEGEEPEEFWNSL------- 593
Query: 196 EGGVASGFRHAEINE---REHVTRLFVCRGKHTVHV-KEVP--FARSSLNHDDIFILDTK 357
G ++ + + E +H RL+ C K V +E+P F + L DD+ +LD
Sbjct: 594 --GGKKDYQTSPLLETQAEDHPPRLYGCSNKTGRFVIEEIPGEFTQDDLAEDDVMLLDAW 651
Query: 358 SKIFQFNGSNSSIQERAKALEVVQYLXDTNHEGK 459
+IF + G +++ E+ ++L+ + +T+ G+
Sbjct: 652 EQIFIWIGKDANEVEKKESLKSAKMYLETDPSGR 685
Score = 31.6 bits (70), Expect = 1.1
Identities = 19/59 (32%), Positives = 34/59 (57%), Gaps = 3/59 (5%)
Frame = +1
Query: 283 TVHVKEVPFARSSLNHDDIFILD--TKSKIFQFNGSNSSIQERAKALEVV-QYLXDTNH 450
TV +E PF+ + L ++ FILD +IF + G +++ QER A++ ++L N+
Sbjct: 264 TVVAEENPFSMAMLLSEECFILDHGAAKQIFVWKGKDANPQERKAAMKTAEEFLQQMNY 322
>ADSV_BOVIN (Q28046) Adseverin (Scinderin) (SC)|
Length = 715
Score = 116 bits (291), Expect = 3e-26
Identities = 63/155 (40%), Positives = 92/155 (59%)
Frame = +1
Query: 13 FQHDIHYWLGKDTSQDESGTAAIKTVELDVALGGRGVQYREVQGNETEKFLSYFKPCIIP 192
F + +H+WLGK+ +QDES AAI TV++D LGG+ VQ RE+QG E+ F+ YFK +
Sbjct: 58 FTYRLHFWLGKECTQDESTAAAIFTVQMDDYLGGKPVQNRELQGYESTDFVGYFKGGLKY 117
Query: 193 EEGGVASGFRHAEINEREHVTRLFVCRGKHTVHVKEVPFARSSLNHDDIFILDTKSKIFQ 372
+ GGVASG H N+ RL +G+ V EVP + S N D FI+D ++I+Q
Sbjct: 118 KAGGVASGLNHVLTNDLT-AQRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQ 176
Query: 373 FNGSNSSIQERAKALEVVQYLXDTNHEGKCDVAAV 477
+ GS+ + ER KA +V + D +G+ + V
Sbjct: 177 WCGSSCNKYERLKASQVAIGIRDNERKGRAQLIVV 211
Score = 60.8 bits (146), Expect = 2e-09
Identities = 55/157 (35%), Positives = 72/157 (45%), Gaps = 12/157 (7%)
Frame = +1
Query: 25 IHYWLGKDTSQDESGTAAIKTVELDVALGGRGVQYREVQGNETEKFLSYF--KPCIIPEE 198
I+ W G + ++DE T+A TV+LD +LGG+ VQ R QG E LS F KP II
Sbjct: 437 IYTWQGANATRDELTTSAFLTVQLDRSLGGQAVQIRVSQGKEPAHLLSLFKDKPLII--- 493
Query: 199 GGVASGFRHAEINEREHVTRLFVCRGK--HTVHVKEVPFARSSLNHDDIFILDTKSKIFQ 372
+G E RLF R + EV +SLN +D+F+L K+ Q
Sbjct: 494 --YKNGTSKKEGQAPAPPIRLFQVRRNLASITRIMEVDVDANSLNSNDVFVL----KLRQ 547
Query: 373 FNG----SNSSIQERAKALE----VVQYLXDTNHEGK 459
NG S QE K E V++ T EGK
Sbjct: 548 NNGYIWIGKGSTQEEEKGAEYVASVLKCKTSTIQEGK 584
Score = 39.3 bits (90), Expect = 0.005
Identities = 36/154 (23%), Positives = 72/154 (46%), Gaps = 6/154 (3%)
Frame = +1
Query: 16 QHDIHYWLGKDTSQDESGTAAIKTVELDVALGGRGVQYREVQGNETEKFLSYFKPCIIPE 195
Q++ + W+GK ++Q+E A L +Q +G E E+F +
Sbjct: 547 QNNGYIWIGKGSTQEEEKGAEYVASVLKCKTST--IQ----EGKEPEEFWNSL------- 593
Query: 196 EGGVASGFRHAEINE---REHVTRLFVCRGKH-TVHVKEVP--FARSSLNHDDIFILDTK 357
G ++ + + E +H RL+ C K ++EVP F + L DD+ +LD
Sbjct: 594 --GGKKDYQTSPLLESQAEDHPPRLYGCSNKTGRFIIEEVPGEFTQDDLAEDDVMLLDAW 651
Query: 358 SKIFQFNGSNSSIQERAKALEVVQYLXDTNHEGK 459
+IF + G +++ E++++L+ + +T+ G+
Sbjct: 652 EQIFIWIGKDANEVEKSESLKSAKIYLETDPSGR 685
Score = 28.9 bits (63), Expect = 7.2
Identities = 29/104 (27%), Positives = 42/104 (40%), Gaps = 3/104 (2%)
Frame = +1
Query: 25 IHYWLGKDTSQDESGTAAIKTVE--LDVALGGRGVQYREV-QGNETEKFLSYFKPCIIPE 195
I W GKD + E AA+KT E L Q + + +G ET F +FK
Sbjct: 293 IFVWKGKDANPQER-KAAMKTAEEFLQQMNYSTNTQIQVLPEGGETPIFKQFFKDW---R 348
Query: 196 EGGVASGFRHAEINEREHVTRLFVCRGKHTVHVKEVPFARSSLN 327
+ + GF + E+ HVK++PF S L+
Sbjct: 349 DRDQSDGFGKVYVTEK-------------VAHVKQIPFDASKLH 379
>GELS_HALRO (O61270) Gelsolin, cytoplasmic (Actin-depolymerizing factor) (ADF)|
(Ascidian gelsolin)
Length = 715
Score = 105 bits (263), Expect = 5e-23
Identities = 60/152 (39%), Positives = 88/152 (57%)
Frame = +1
Query: 13 FQHDIHYWLGKDTSQDESGTAAIKTVELDVALGGRGVQYREVQGNETEKFLSYFKPCIIP 192
F+ ++HYW GK++SQDE G AI V++D L G V++REVQGNE+ F F P I
Sbjct: 57 FEWNLHYWQGKESSQDERGAVAILAVKMDDHLNGGPVEHREVQGNESAAFKGLF-PTITY 115
Query: 193 EEGGVASGFRHAEINEREHVTRLFVCRGKHTVHVKEVPFARSSLNHDDIFILDTKSKIFQ 372
GGVASGF H EINE E L +GK V +VP +SL D ++ D +I+
Sbjct: 116 LIGGVASGFTHVEINEVEDRKVLTRVKGKRPVRATQVPIKWTSLTDSDSYVFDIGKEIYV 175
Query: 373 FNGSNSSIQERAKALEVVQYLXDTNHEGKCDV 468
++G +S E+ KA++ L + +G+ ++
Sbjct: 176 WSGPKASHFEKNKAIQYADGLKN-ERQGRAEL 206
Score = 37.7 bits (86), Expect = 0.015
Identities = 37/146 (25%), Positives = 58/146 (39%), Gaps = 3/146 (2%)
Frame = +1
Query: 25 IHYWLGKDTSQDESGTAAIKTVEL-DVALGGRGVQYREVQGNETEKFLSYF--KPCIIPE 195
++YW G S +E I+T + G Q R VQG E + F KP I+
Sbjct: 437 LYYWQGNKASINERTALPIQTKNTHETECDGNASQIRVVQGTEPPHMMMLFGGKPLIVHL 496
Query: 196 EGGVASGFRHAEINEREHVTRLFVCRGKHTVHVKEVPFARSSLNHDDIFILDTKSKIFQF 375
++ + + R + + F V EVP S LN +D F+L T S + +
Sbjct: 497 GDTISPTGKSKAASTRLYQVQSFFAGRCRAV---EVPAKSSHLNSNDAFLLITPSGSYIW 553
Query: 376 NGSNSSIQERAKALEVVQYLXDTNHE 453
G + E A + L + +E
Sbjct: 554 VGKGAVESEIQGAKDTAGILKISKYE 579
>CAPG_MOUSE (P24452) Macrophage capping protein (Myc basic motif homolog 1)|
(Actin-capping protein GCAP39)
Length = 352
Score = 105 bits (262), Expect = 6e-23
Identities = 58/153 (37%), Positives = 84/153 (54%), Gaps = 2/153 (1%)
Frame = +1
Query: 25 IHYWLGKDTSQDESGTAAIKTVELDVALGGRGVQYREVQGNETEKFLSYF-KPCIIPEEG 201
+H W+G+ +S+DE G A+ V L+ LG R VQ+REVQGNE++ F+SYF + EG
Sbjct: 61 LHLWIGQQSSRDEQGACAVLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYYREG 120
Query: 202 GVASGFRHAEINER-EHVTRLFVCRGKHTVHVKEVPFARSSLNHDDIFILDTKSKIFQFN 378
GV S F R + +L+ +GK + E P + S N D FILD IF +
Sbjct: 121 GVESAFHKTTSGARGAAIRKLYQVKGKKNIRATERPLSWDSFNTGDCFILDLGQNIFAWC 180
Query: 379 GSNSSIQERAKALEVVQYLXDTNHEGKCDVAAV 477
G S+I ER KA ++ + D+ +GK V +
Sbjct: 181 GGKSNILERNKARDLALAIRDSERQGKAQVEII 213
Score = 28.5 bits (62), Expect = 9.4
Identities = 16/42 (38%), Positives = 25/42 (59%), Gaps = 2/42 (4%)
Frame = +1
Query: 304 PFARSSLNHDDIFILDTK--SKIFQFNGSNSSIQERAKALEV 423
PFA L DD F+LD ++I+ + G ++ +ER AL+V
Sbjct: 275 PFASELLIPDDCFVLDNGLCAQIYIWKGRKANEKERQAALQV 316
>VILL_HUMAN (O15195) Villin-like protein|
Length = 856
Score = 104 bits (260), Expect = 1e-22
Identities = 56/145 (38%), Positives = 81/145 (55%)
Frame = +1
Query: 22 DIHYWLGKDTSQDESGTAAIKTVELDVALGGRGVQYREVQGNETEKFLSYFKPCIIPEEG 201
D+HYW+GK + G A L LGG+ V +RE QG+E++ F SYF+P II +G
Sbjct: 59 DLHYWVGKQAGAEAQGAAEAFQQRLQDELGGQTVLHREAQGHESDCFCSYFRPGIIYRKG 118
Query: 202 GVASGFRHAEINEREHVTRLFVCRGKHTVHVKEVPFARSSLNHDDIFILDTKSKIFQFNG 381
G+AS +H E N ++ RL +G+ V EV + +S N DIF+LD + Q+NG
Sbjct: 119 GLASDLKHVETN-LFNIQRLLHIKGRKHVSATEVELSWNSFNKGDIFLLDLGKMMIQWNG 177
Query: 382 SNSSIQERAKALEVVQYLXDTNHEG 456
+SI E+A+ L + L D G
Sbjct: 178 PKTSISEKARGLALTYSLRDRERGG 202
Score = 63.2 bits (152), Expect = 3e-10
Identities = 49/153 (32%), Positives = 64/153 (41%), Gaps = 4/153 (2%)
Frame = +1
Query: 7 GSFQHDIHYWLGKDTSQDESGTAAIKTVELDVALGGRGVQYREVQGNETEKFLSYFKP-- 180
G Q+ ++ W G + DE ELDV GG VQ G+E FL+ F+
Sbjct: 430 GRVQYILYLWQGHQATADEIEALNSNAEELDVMYGGVLVQEHVTMGSEPPHFLAIFQGQL 489
Query: 181 CIIPEEGGVASGFRHAEINEREHVTRLFVCRG--KHTVHVKEVPFARSSLNHDDIFILDT 354
I E G H + TRLF +G H EVP SSLN DIF+L T
Sbjct: 490 VIFQERAG------HHGKGQSASTTRLFQVQGTDSHNTRTMEVPARASSLNSSDIFLLVT 543
Query: 355 KSKIFQFNGSNSSIQERAKALEVVQYLXDTNHE 453
S + + G + +R A VV + N E
Sbjct: 544 ASVCYLWFGKGCNGDQREMARVVVTVISRKNEE 576
Score = 30.0 bits (66), Expect = 3.2
Identities = 36/135 (26%), Positives = 52/135 (38%), Gaps = 8/135 (5%)
Frame = +1
Query: 34 WLGKDTSQDESGTAAIKTVEL-DVALGGRGVQYREVQGNETEKFLSYFKPCIIPEE-GGV 207
W G TS E T L D GG Q V L ++ G +
Sbjct: 175 WNGPKTSISEKARGLALTYSLRDRERGGGRAQIGVVDDEAKAPDLMQIMEAVLGRRVGSL 234
Query: 208 ASGFRHAEINEREHVT-RLFVC--RGKHTV--HVKEVPFARSSLNHDDIFILDTKS-KIF 369
+ +IN+ + RL+ +GK V + P + L +D +ILD KI+
Sbjct: 235 RAATPSKDINQLQKANVRLYHVYEKGKDLVVLELATPPLTQDLLQEEDFYILDQGGFKIY 294
Query: 370 QFNGSNSSIQERAKA 414
+ G SS+QER A
Sbjct: 295 VWQGRMSSLQERKAA 309
>VILL_MOUSE (Q91YD6) Villin-like protein (EF-6)|
Length = 859
Score = 100 bits (250), Expect = 1e-21
Identities = 61/153 (39%), Positives = 88/153 (57%), Gaps = 1/153 (0%)
Frame = +1
Query: 22 DIHYWLGKDTSQDESGTAAIKTVE-LDVALGGRGVQYREVQGNETEKFLSYFKPCIIPEE 198
D+HYW+GKD S E+ AA+ V+ L LG + V +RE QG+E++ F SYF P +I +
Sbjct: 61 DLHYWIGKDASA-EAREAAVSFVQCLQEDLGDQTVLHRESQGHESDCFHSYFHPGVIYRK 119
Query: 199 GGVASGFRHAEINEREHVTRLFVCRGKHTVHVKEVPFARSSLNHDDIFILDTKSKIFQFN 378
GG S + AE N +V RL +G+ V EV + +S N DIF+LD + Q+N
Sbjct: 120 GGRDSALKFAETN-MYNVQRLLHIKGRKHVSATEVALSWNSFNKGDIFLLDLGKVMIQWN 178
Query: 379 GSNSSIQERAKALEVVQYLXDTNHEGKCDVAAV 477
G +SI E+A+AL + L D G+ +A V
Sbjct: 179 GPKASISEKARALTLTCNLRDRERGGRAQIAVV 211
Score = 52.0 bits (123), Expect = 8e-07
Identities = 39/153 (25%), Positives = 63/153 (41%), Gaps = 2/153 (1%)
Frame = +1
Query: 1 KNGSFQHDIHYWLGKDTSQDESGTAAIKTVELDVALGGRGVQYREVQGNETEKFLSYFKP 180
K G Q+ ++ W G ++ +++ ELD+ G Q G+E FL+ F+
Sbjct: 428 KLGCVQYLLYLWQGHQSTVEDTKALNCSAEELDLMHQGALAQGHVTMGSEPPHFLAIFQG 487
Query: 181 CIIPEEGGVASGFRHAEINEREHVTRLFVCRG--KHTVHVKEVPFARSSLNHDDIFILDT 354
++ +G + +++ TRLF +G H EVP SSL D+F L T
Sbjct: 488 RLVVFQGNAGNKGERPPVSD----TRLFHVQGTESHNTRTMEVPARASSLTSGDVFFLIT 543
Query: 355 KSKIFQFNGSNSSIQERAKALEVVQYLXDTNHE 453
+ + G +R A VV N E
Sbjct: 544 SHVCYLWFGKGCHGDQREMARTVVSVFPGNNKE 576
Score = 30.8 bits (68), Expect = 1.9
Identities = 34/135 (25%), Positives = 51/135 (37%), Gaps = 7/135 (5%)
Frame = +1
Query: 34 WLGKDTSQDESGTAAIKTVEL-DVALGGRGVQYREVQGNETEKFLSYFKPCIIPEEGGVA 210
W G S E A T L D GGR NE L + + G +
Sbjct: 177 WNGPKASISEKARALTLTCNLRDRERGGRAQIAVVDAENEATNLLRIMEAVLGCRSGSLC 236
Query: 211 SGFRHAEINE--REHVTRLFVCRGKHTVHVKEV---PFARSSLNHDDIFILDTKS-KIFQ 372
+++ + +V VC + V+E+ P + L D ++LD KI+
Sbjct: 237 PSVPSNSVSQLQKANVRLYHVCEKGTDLVVQELATRPLTQDLLQEDGCYLLDQGGFKIYM 296
Query: 373 FNGSNSSIQERAKAL 417
+ G SS QE+ AL
Sbjct: 297 WQGRKSSPQEKKAAL 311
>FLII_DROME (Q24020) Protein flightless-1 (Flightless-I)|
Length = 1256
Score = 81.6 bits (200), Expect = 9e-16
Identities = 53/156 (33%), Positives = 84/156 (53%), Gaps = 2/156 (1%)
Frame = +1
Query: 7 GSFQHDIHYWLGKDTSQDESGTAAIKTVELDVALGGRGVQYREVQGNETEKFLSYFKPCI 186
G +I +W+G + + D+ AAI V L LG R RE QG+E+E+FLS F+ +
Sbjct: 537 GLLDWEIFFWIGNEATLDKRACAAIHAVNLRNFLGARCRTVREEQGDESEQFLSLFETEV 596
Query: 187 IPEEGG-VASGFRHAEINEREHVTRLFVCRG-KHTVHVKEVPFARSSLNHDDIFILDTKS 360
I EGG A+GF I E H+TRL++ T+H++ V A +SL+ F+LD +
Sbjct: 597 IYIEGGRTATGF--YTIEEMIHITRLYLVHAYGATIHLEPVAPAITSLDPRHAFVLDLGT 654
Query: 361 KIFQFNGSNSSIQERAKALEVVQYLXDTNHEGKCDV 468
I+ + G S +KA + + + T + KC++
Sbjct: 655 HIYIWMGERSKNTLNSKARLMAEKISKTERKNKCEI 690
Score = 35.8 bits (81), Expect = 0.059
Identities = 29/80 (36%), Positives = 37/80 (46%), Gaps = 5/80 (6%)
Frame = +1
Query: 205 VASGFRHAEINEREHV--TRLFVC---RGKHTVHVKEVPFARSSLNHDDIFILDTKSKIF 369
VA G R + E++ TRLF C RG +TV K F + L DDI ILD +F
Sbjct: 1134 VALGGRKPYDTDAEYMNYTRLFRCSNERGYYTVAEKCADFCQDDLADDDIMILDNGEHVF 1193
Query: 370 QFNGSNSSIQERAKALEVVQ 429
+ G S E A + Q
Sbjct: 1194 LWMGPRCSEVEVKLAYKSAQ 1213
>GELS_XENLA (P14885) Gelsolin (Actin-depolymerizing factor) (ADF) (Brevin)|
(Fragment)
Length = 417
Score = 66.6 bits (161), Expect = 3e-11
Identities = 53/150 (35%), Positives = 75/150 (50%), Gaps = 5/150 (3%)
Frame = +1
Query: 1 KNGSFQHDIHY-WLGKDTSQDESGTAAIKTVELDVALGGRGVQYREVQGNETEKFLSYF- 174
K+G Q I Y W G D+++DE +AI + +LD LGG VQ R VQG E +S F
Sbjct: 117 KSGGKQGQIIYTWQGDDSTKDEITASAILSAQLDEELGGGPVQVRVVQGKEPAHLISLFG 176
Query: 175 -KPCIIPEEGGVASGFRHAEINEREHVTRLFVCRGKHT--VHVKEVPFARSSLNHDDIFI 345
KP II + G G + + N RLF R + EV S+LN +D F+
Sbjct: 177 GKPMIIYKGGTSREGGQTKDAN-----VRLFQVRTSSSGFSRAVEVDNTASNLNSNDAFV 231
Query: 346 LDTKSKIFQFNGSNSSIQERAKALEVVQYL 435
L T S + + G S+ E+ A E+++ L
Sbjct: 232 LTTPSASYLWVGQGSTNVEKNGAKELLKIL 261
Score = 35.8 bits (81), Expect = 0.059
Identities = 35/135 (25%), Positives = 60/135 (44%), Gaps = 5/135 (3%)
Frame = +1
Query: 28 HYWLGKDTSQDESGTAAIKTVELDVALGGRGVQYREVQGNETEKFLSYFKPCIIPEEGGV 207
+ W+G+ ++ E A EL LG + E G ET+ F GG
Sbjct: 239 YLWVGQGSTNVEKNGAK----ELLKILGVSASEIPE--GQETDDFWGAL--------GGK 284
Query: 208 ASGFRHAEINER--EHVTRLFVCRGKH-TVHVKEVP--FARSSLNHDDIFILDTKSKIFQ 372
A A + ++ H RLF C K ++EVP ++ L DD+ +LDT +++
Sbjct: 285 ADYRTSARLKDKLNAHPPRLFACSNKTGRFIIEEVPGEISQDDLATDDVMLLDTWDQVYV 344
Query: 373 FNGSNSSIQERAKAL 417
+ G+ + E+ +A+
Sbjct: 345 WVGNEAQEDEKKEAI 359
>FLII_CAEEL (P34268) Protein flightless-1 homolog|
Length = 1257
Score = 66.6 bits (161), Expect = 3e-11
Identities = 51/157 (32%), Positives = 77/157 (49%), Gaps = 2/157 (1%)
Frame = +1
Query: 4 NGSFQHDIHYWLGKDTSQDESGTAAIKTVELDVALGGRGVQYREVQGNETEKFLSYFKPC 183
+G +H I YWLG+ S D+ +A+ V L L RE +ETE+FL+ F
Sbjct: 547 SGQLRHAIFYWLGEHASLDKGMCSAVHAVGLRNHLNATCRTQREEMNDETEEFLTLFGEE 606
Query: 184 IIPEEGG-VASGFRHAEINEREHVTRLFVCRGKHT-VHVKEVPFARSSLNHDDIFILDTK 357
I+ EGG SGF E + H+TRL+ T V ++ VP + SL+ F+LD
Sbjct: 607 IVYIEGGRTISGFYTTE--KPAHLTRLYRAGVNGTAVEMEPVPLSVESLDPRFCFLLDAG 664
Query: 358 SKIFQFNGSNSSIQERAKALEVVQYLXDTNHEGKCDV 468
I+ ++G S I KA + L + +GK ++
Sbjct: 665 ETIWIWSGYKSRITVSNKARLFAERLNKRDRKGKSEI 701
Score = 43.5 bits (101), Expect = 3e-04
Identities = 39/140 (27%), Positives = 63/140 (45%), Gaps = 5/140 (3%)
Frame = +1
Query: 25 IHYWLGKDTSQDESGTAAIKTVELDVALGGRGVQYREVQGNETEKFLSYFKPCIIPEEGG 204
++ W+GKD+ E A + V D+ + +R V+ E E+ ++K
Sbjct: 1086 VYVWMGKDSDPREHEFA--RQVASDLVVRDDDNDFRIVEVQEGEENEEFWK--------- 1134
Query: 205 VASGFRHAEINER--EHVTRLFVC---RGKHTVHVKEVPFARSSLNHDDIFILDTKSKIF 369
V G + E + +H TRLF C +G + K V F + L+ DDI ILD +F
Sbjct: 1135 VLGGKKKYETDSSFVKH-TRLFRCTNEKGYFAISEKTVDFCQDDLDDDDIMILDNGDAVF 1193
Query: 370 QFNGSNSSIQERAKALEVVQ 429
+ G+ SS E + + Q
Sbjct: 1194 LWIGARSSDIEAKLSYQAAQ 1213
>VILI_DICDI (P36418) Protovillin (100 kDa actin-binding protein)|
Length = 959
Score = 66.2 bits (160), Expect = 4e-11
Identities = 50/160 (31%), Positives = 77/160 (48%), Gaps = 19/160 (11%)
Frame = +1
Query: 19 HDIHYWLGK--DTSQDESGTAAIKTVELDVALGGRGVQ------------YREVQGNETE 156
++IH+W+G+ SQ+ + EL+ + Q YRE QG E +
Sbjct: 100 YNIHFWIGELLINSQETINFCNDRIEELERIIKYNQKQFDSEQFYPEPILYREFQGKEGD 159
Query: 157 KFLSYFKPC-----IIPEEGGVASGFRHAEINEREHVTRLFVCRGKHTVHVKEVPFARSS 321
F+SYFK + P + AS A I +LF +G+ + VK+V + S
Sbjct: 160 IFMSYFKSYGGPRYVAPLKLTSAS----AAIATAAKQYKLFHLKGRRNIRVKQVDISSKS 215
Query: 322 LNHDDIFILDTKSKIFQFNGSNSSIQERAKALEVVQYLXD 441
LN D+F+LD + I+Q+NGS SS E+ K L++ L D
Sbjct: 216 LNSGDVFVLDCEDFIYQWNGSESSRLEKGKGLDLTIRLRD 255
Score = 46.6 bits (109), Expect = 3e-05
Identities = 35/143 (24%), Positives = 63/143 (44%), Gaps = 3/143 (2%)
Frame = +1
Query: 4 NGSFQHDIHYWLGKDTSQDESGTAAIKTVELDVALGGRGVQYREVQGNETEKFLSYFKPC 183
+GS ++YW G+ +S ++ G AA+ ++ L + R VQ E FL +F+
Sbjct: 508 DGSNNSILYYWQGRFSSSEDKGAAALLAKDVGKELHRSCIHVRTVQNKEPNHFLEHFQGR 567
Query: 184 IIPEEGGVASGFRHAEI-NEREHVTRLFVCRGKH--TVHVKEVPFARSSLNHDDIFILDT 354
++ +G + + N + L+ RG +H +V A SSL+ +D FIL
Sbjct: 568 MVVFKGSRPNATTEVSLENLSSSLQGLYHVRGTEPINIHSIQVEKAISSLDSNDSFILVN 627
Query: 355 KSKIFQFNGSNSSIQERAKALEV 423
+ E+ AL++
Sbjct: 628 FKNTISYIWVGKYSDEKEAALQI 650
Score = 38.9 bits (89), Expect = 0.007
Identities = 39/140 (27%), Positives = 63/140 (45%), Gaps = 3/140 (2%)
Frame = +1
Query: 10 SFQHDIHY-WLGKDTSQDESGTAAIKTVELDVALGGRGVQYREVQGNETEKFLSYFKPCI 186
+F++ I Y W+GK + + E+ V G Q + +G+ET +F +
Sbjct: 627 NFKNTISYIWVGKYSDEKEAALQISSNV-----FTGYNFQLID-EGDETSEFWESLETN- 679
Query: 187 IPEEGGVASGFRHAEINEREHVTRLFVCRGKHTVH-VKEV-PFARSSLNHDDIFILDTKS 360
+ + E+E TRLF C V V E+ F++ L+ DD+ ILD +
Sbjct: 680 -SSLSLLKDYYTQLRTVEQEKKTRLFQCSNNSGVFKVFEIHDFSQDDLDSDDVMILDNQK 738
Query: 361 KIFQFNGSNSSIQERAKALE 420
+IF + G SS E+ A E
Sbjct: 739 QIFVWVGKESSDTEKLMANE 758
>VILD_DICDI (Q8WQ85) Villidin|
Length = 1704
Score = 65.1 bits (157), Expect = 9e-11
Identities = 46/151 (30%), Positives = 76/151 (50%), Gaps = 2/151 (1%)
Frame = +1
Query: 1 KNGSFQHDIHYWLGKDTSQDESGTAAIKTVELDVALGGRGVQYREVQGNETEKFLSYFKP 180
+N H I+Y+LG+D+S +E GT+A TV+L+ +L G VQ R V E + FL+ FK
Sbjct: 1330 QNNKEAHVIYYYLGRDSSINEKGTSAYLTVDLNESLVGACVQTRVVANKECKNFLNLFKT 1389
Query: 181 CIIPEEGGVASGFRHAEINEREHVTRLFVCRGKHTVHVK--EVPFARSSLNHDDIFILDT 354
++ +G N L+ +G + ++ +V F+ S LN + IL T
Sbjct: 1390 KMVIHKGKYN--------NYDPKKPSLYQVKGLDKIDIRAVQVEFSSSMLNTLHVSILRT 1441
Query: 355 KSKIFQFNGSNSSIQERAKALEVVQYLXDTN 447
KI+ ++G S E+ AL + + T+
Sbjct: 1442 PEKIYIWHGKFSLDAEQNSALSIAENFNSTS 1472
Score = 42.4 bits (98), Expect = 6e-04
Identities = 24/67 (35%), Positives = 35/67 (52%)
Frame = +1
Query: 259 LFVCRGKHTVHVKEVPFARSSLNHDDIFILDTKSKIFQFNGSNSSIQERAKALEVVQYLX 438
L +GK + V+ V + SSLN + FILD +IF + GS +S +AKAL+ +
Sbjct: 1029 LIQVKGKRKIRVRMVKLSTSSLNCHNSFILDAGPRIFVWAGSKTSRVNKAKALDFANRIR 1088
Query: 439 DTNHEGK 459
GK
Sbjct: 1089 TKERGGK 1095
Score = 36.6 bits (83), Expect = 0.034
Identities = 30/114 (26%), Positives = 52/114 (45%), Gaps = 8/114 (7%)
Frame = +1
Query: 139 QGNETEKFLSYFKPCIIPEEGGVASGFRHAEINEREHVT------RLFVCRGKHTVH--V 294
+G+E+ +F S F+ GG F I T R FVC +
Sbjct: 1480 EGSESNEFWSAFE-----STGGRQKYFNDIMIQSSSIPTSFTYKPRFFVCSNASGIVEVT 1534
Query: 295 KEVPFARSSLNHDDIFILDTKSKIFQFNGSNSSIQERAKALEVVQYLXDTNHEG 456
+E PF++ L+ + ILD +S I+ + GS ++ + + ++EVV +T+ G
Sbjct: 1535 EESPFSQDDLDIGSVCILDVQSHIYLWIGSRATHRTKRASMEVVLNFIETSKLG 1588
>NANE_STAAS (Q6GCF3) Putative N-acetylmannosamine-6-phosphate 2-epimerase (EC|
5.1.3.9) (ManNAc-6-P epimerase)
Length = 222
Score = 28.5 bits (62), Expect = 9.4
Identities = 30/112 (26%), Positives = 49/112 (43%), Gaps = 11/112 (9%)
Frame = +1
Query: 175 KPCIIPEEGGVASGFRHAEINEREHVTRLFVCRGKHTVHVKEVPFARSSLNHDDIFILDT 354
K + EGG A G R N +E + + K TV + + + NH D+FI T
Sbjct: 26 KMALAAYEGG-AVGIR---ANTKEDILAI-----KETVDLPVIGIVKRDYNHSDVFITAT 76
Query: 355 KSKIFQFNGS-------NSSIQERAKAL--EVVQYLXD--TNHEGKCDVAAV 477
++ + S ++++Q+R K E+V Y+ N E D+A V
Sbjct: 77 SKEVDELIESQCEVIALDATLQQRPKETLDELVSYIRTHAPNVEIMADIATV 128
Database: uniprot_sprot.fasta
Posted date: May 25, 2006 5:36 PM
Number of letters in database: 80,573,946
Number of sequences in database: 219,361
Lambda K H
0.317 0.135 0.395
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 70,560,324
Number of Sequences: 219361
Number of extensions: 1478840
Number of successful extensions: 3944
Number of sequences better than 10.0: 52
Number of HSP's better than 10.0 without gapping: 3731
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3894
length of database: 80,573,946
effective HSP length: 103
effective length of database: 57,979,763
effective search space used: 3188886965
frameshift window, decay const: 50, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)