ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | bart60b01 |
|---|---|
| Clone Library Name | barley_pub |
>BRI1_LYCPE (Q8L899) Systemin receptor SR160 precursor (EC 2.7.11.1)| (Brassinosteroid LRR receptor kinase) Length = 1207 Score = 88.6 bits (218), Expect = 7e-18 Identities = 56/121 (46%), Positives = 72/121 (59%), Gaps = 7/121 (5%) Frame = +1 Query: 103 VLAGNRSSGLTPLDWEARSAIALATARGVAHIHSTG-PTASHGNIKSSNVLLTKSYEARV 279 VL + +G+ L+W AR IA+ ARG+A +H P H ++KSSNVLL ++ EARV Sbjct: 972 VLHDRKKTGIK-LNWPARRKIAIGAARGLAFLHHNCIPHIIHRDMKSSNVLLDENLEARV 1030 Query: 280 SDHGLPTLVGPSFSPTRVS------GYRAPEVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 SD G+ L+ + VS GY PE R S K DVYS+GV+LLELLTGK P Sbjct: 1031 SDFGMARLMSAMDTHLSVSTLAGTPGYVPPEYYQSFRCSTKGDVYSYGVVLLELLTGKQP 1090 Query: 442 T 444 T Sbjct: 1091 T 1091
>BRI1_ARATH (O22476) BRASSINOSTEROID INSENSITIVE 1 precursor (EC 2.7.11.1)| (AtBRI1) (Brassinosteroid LRR receptor kinase) Length = 1196 Score = 88.2 bits (217), Expect = 9e-18 Identities = 52/109 (47%), Positives = 67/109 (61%), Gaps = 7/109 (6%) Frame = +1 Query: 139 LDWEARSAIALATARGVAHIH-STGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPS 315 L+W R IA+ +ARG+A +H + P H ++KSSNVLL ++ EARVSD G+ L+ Sbjct: 978 LNWSTRRKIAIGSARGLAFLHHNCSPHIIHRDMKSSNVLLDENLEARVSDFGMARLMSAM 1037 Query: 316 FSPTRVS------GYRAPEVTDIRRVSQKADVYSFGVLLLELLTGKAPT 444 + VS GY PE R S K DVYS+GV+LLELLTGK PT Sbjct: 1038 DTHLSVSTLAGTPGYVPPEYYQSFRCSTKGDVYSYGVVLLELLTGKRPT 1086
>RLK5_ARATH (P47735) Receptor-like protein kinase 5 precursor (EC 2.7.11.1)| Length = 999 Score = 87.8 bits (216), Expect = 1e-17 Identities = 53/129 (41%), Positives = 78/129 (60%), Gaps = 9/129 (6%) Frame = +1 Query: 103 VLAGNRSSGLTPLDWEARSAIALATARGVAHIH-STGPTASHGNIKSSNVLLTKSYEARV 279 VL G+R G+ L W R IAL A G++++H P H ++KSSN+LL Y A+V Sbjct: 777 VLHGDRKGGVV-LGWPERLRIALDAAEGLSYLHHDCVPPIVHRDVKSSNILLDSDYGAKV 835 Query: 280 SDHGLPTL--VGPSFSPTRVSG------YRAPEVTDIRRVSQKADVYSFGVLLLELLTGK 435 +D G+ + + S +P +SG Y APE RV++K+D+YSFGV+LLEL+TGK Sbjct: 836 ADFGIAKVGQMSGSKTPEAMSGIAGSCGYIAPEYVYTLRVNEKSDIYSFGVVLLELVTGK 895 Query: 436 APTHAVVNE 462 PT + + + Sbjct: 896 QPTDSELGD 904
>BRI1_LYCES (Q8GUQ5) Brassinosteroid LRR receptor kinase precursor (EC 2.7.11.1)| (tBRI1) (Altered brassinolide sensitivity 1) (Systemin receptor SR160) Length = 1207 Score = 87.4 bits (215), Expect = 2e-17 Identities = 53/109 (48%), Positives = 66/109 (60%), Gaps = 7/109 (6%) Frame = +1 Query: 139 LDWEARSAIALATARGVAHIHSTG-PTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPS 315 L+W AR IA+ ARG+A +H P H ++KSSNVLL ++ EARVSD G+ L+ Sbjct: 983 LNWPARRKIAIGAARGLAFLHHNCIPHIIHRDMKSSNVLLDENLEARVSDFGMARLMSAM 1042 Query: 316 FSPTRVS------GYRAPEVTDIRRVSQKADVYSFGVLLLELLTGKAPT 444 + VS GY PE R S K DVYS+GV+LLELLTGK PT Sbjct: 1043 DTHLSVSTLAGTPGYVPPEYYQSFRCSTKGDVYSYGVVLLELLTGKQPT 1091
>BRL1_ARATH (Q9ZWC8) Serine/threonine-protein kinase BRI1-like 1 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 1) Length = 1166 Score = 86.7 bits (213), Expect = 3e-17 Identities = 52/108 (48%), Positives = 66/108 (61%), Gaps = 7/108 (6%) Frame = +1 Query: 139 LDWEARSAIALATARGVAHIH-STGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPS 315 L+W AR IA+ ARG+A +H S P H ++KSSNVLL + +EARVSD G+ LV Sbjct: 956 LNWAARKKIAIGAARGLAFLHHSCIPHIIHRDMKSSNVLLDEDFEARVSDFGMARLVSAL 1015 Query: 316 FSPTRVS------GYRAPEVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 + VS GY PE R + K DVYS+GV+LLELL+GK P Sbjct: 1016 DTHLSVSTLAGTPGYVPPEYYQSFRCTAKGDVYSYGVILLELLSGKKP 1063
>BRL3_ARATH (Q9LJF3) Serine/threonine-protein kinase BRI1-like 3 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 3) Length = 1164 Score = 86.3 bits (212), Expect = 4e-17 Identities = 52/108 (48%), Positives = 65/108 (60%), Gaps = 7/108 (6%) Frame = +1 Query: 139 LDWEARSAIALATARGVAHIH-STGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPS 315 LDW AR IA+ ARG+A +H S P H ++KSSNVLL + + ARVSD G+ LV Sbjct: 954 LDWSARKKIAIGAARGLAFLHHSCIPHIIHRDMKSSNVLLDQDFVARVSDFGMARLVSAL 1013 Query: 316 FSPTRVS------GYRAPEVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 + VS GY PE R + K DVYS+GV+LLELL+GK P Sbjct: 1014 DTHLSVSTLAGTPGYVPPEYYQSFRCTAKGDVYSYGVILLELLSGKKP 1061
>RLCK7_ARATH (Q9LQQ8) Probable serine/threonine-protein kinase RLCKVII (EC| 2.7.11.1) Length = 423 Score = 84.3 bits (207), Expect = 1e-16 Identities = 48/112 (42%), Positives = 68/112 (60%), Gaps = 8/112 (7%) Frame = +1 Query: 124 SGLTPLDWEARSAIALATARGVAHIHST-GPTASHGNIKSSNVLLTKSYEARVSDHGLPT 300 SG PLDW R IA ARG+ ++H P + ++K SN+LL + Y+ ++SD GL Sbjct: 194 SGKKPLDWNTRMKIAAGAARGLEYLHDRMTPPVIYRDLKCSNILLGEDYQPKLSDFGLAK 253 Query: 301 LVGPSFSPTRVS-------GYRAPEVTDIRRVSQKADVYSFGVLLLELLTGK 435 VGPS T VS GY AP+ +++ K+D+YSFGV+LLEL+TG+ Sbjct: 254 -VGPSGDKTHVSTRVMGTYGYCAPDYAMTGQLTFKSDIYSFGVVLLELITGR 304
>NAK_ARATH (P43293) Probable serine/threonine-protein kinase NAK (EC 2.7.11.1)| Length = 389 Score = 84.0 bits (206), Expect = 2e-16 Identities = 50/113 (44%), Positives = 67/113 (59%), Gaps = 7/113 (6%) Frame = +1 Query: 118 RSSGLTPLDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLP 297 R + PL W R +AL ARG+A +H+ P + + K+SN+LL +Y A++SD GL Sbjct: 166 RGTFYQPLSWNTRVRMALGAARGLAFLHNAQPQVIYRDFKASNILLDSNYNAKLSDFGL- 224 Query: 298 TLVGP----SFSPTRV---SGYRAPEVTDIRRVSQKADVYSFGVLLLELLTGK 435 GP S TRV GY APE +S K+DVYSFGV+LLELL+G+ Sbjct: 225 ARDGPMGDNSHVSTRVMGTQGYAAPEYLATGHLSVKSDVYSFGVVLLELLSGR 277
>EXS_ARATH (Q9LYN8) Leucine-rich repeat receptor protein kinase EXS precursor| (EC 2.7.11.1) (Extra sporogenous cells protein) (EXCESS MICROSPOROCYTES1 protein) Length = 1192 Score = 84.0 bits (206), Expect = 2e-16 Identities = 50/116 (43%), Positives = 65/116 (56%), Gaps = 6/116 (5%) Frame = +1 Query: 115 NRSSGLTPLDWEARSAIALATARGVAHIHSTG-PTASHGNIKSSNVLLTKSYEARVSDHG 291 N++ L LDW R IA+ ARG+A +H P H +IK+SN+LL +E +V+D G Sbjct: 1004 NQTGMLEVLDWSKRLKIAVGAARGLAFLHHGFIPHIIHRDIKASNILLDGDFEPKVADFG 1063 Query: 292 LPTLVGPSFSPTRVS-----GYRAPEVTDIRRVSQKADVYSFGVLLLELLTGKAPT 444 L L+ S GY PE R + K DVYSFGV+LLEL+TGK PT Sbjct: 1064 LARLISACESHVSTVIAGTFGYIPPEYGQSARATTKGDVYSFGVILLELVTGKEPT 1119
>TMKL1_ARATH (P33543) Putative kinase-like protein TMKL1 precursor| Length = 674 Score = 81.3 bits (199), Expect = 1e-15 Identities = 45/108 (41%), Positives = 70/108 (64%), Gaps = 7/108 (6%) Frame = +1 Query: 139 LDWEARSAIALATARGVAHIHSTGPTAS--HGNIKSSNVLLTKSYEARVSDHGLPTLVGP 312 L+W R IAL ARG+A++H TG HGNI+S NVL+ + AR+++ GL ++ Sbjct: 469 LNWARRHKIALGIARGLAYLH-TGQEVPIIHGNIRSKNVLVDDFFFARLTEFGLDKIMVQ 527 Query: 313 SFSPTRVS-----GYRAPEVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 + + VS GY+APE+ +++ + ++DVY+FG+LLLE+L GK P Sbjct: 528 AVADEIVSQAKSDGYKAPELHKMKKCNPRSDVYAFGILLLEILMGKKP 575
>NORK_MEDTR (Q8L4H4) Nodulation receptor kinase precursor (EC 2.7.11.1) (Does not| make infections protein 2) (Symbiosis receptor-like kinase) (MtSYMRK) Length = 925 Score = 80.9 bits (198), Expect = 1e-15 Identities = 45/108 (41%), Positives = 70/108 (64%), Gaps = 7/108 (6%) Frame = +1 Query: 139 LDWEARSAIALATARGVAHIHS-TGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLV--- 306 LDW R +IAL ARG+A++H+ G + H ++KSSN+LL +S A+V+D G Sbjct: 691 LDWPTRLSIALGAARGLAYLHTFPGRSVIHRDVKSSNILLDQSMCAKVADFGFSKYAPQE 750 Query: 307 GPSFSPTRV---SGYRAPEVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 G S+ V +GY PE +++S+K+DV+SFGV+LLE+++G+ P Sbjct: 751 GDSYVSLEVRGTAGYLDPEYYKTQQLSEKSDVFSFGVVLLEIVSGREP 798
>TMK1_ARATH (P43298) Putative receptor protein kinase TMK1 precursor (EC| 2.7.11.1) Length = 942 Score = 80.9 bits (198), Expect = 1e-15 Identities = 48/109 (44%), Positives = 65/109 (59%), Gaps = 6/109 (5%) Frame = +1 Query: 127 GLTPLDWEARSAIALATARGVAHIHSTGPTAS-HGNIKSSNVLLTKSYEARVSDHGLPTL 303 GL PL W+ R +AL ARGV ++H + H ++K SN+LL A+V+D GL L Sbjct: 682 GLKPLLWKQRLTLALDVARGVEYLHGLAHQSFIHRDLKPSNILLGDDMRAKVADFGLVRL 741 Query: 304 V--GPSFSPTRVSG---YRAPEVTDIRRVSQKADVYSFGVLLLELLTGK 435 G TR++G Y APE RV+ K DVYSFGV+L+EL+TG+ Sbjct: 742 APEGKGSIETRIAGTFGYLAPEYAVTGRVTTKVDVYSFGVILMELITGR 790
>CRI4_MAIZE (O24585) Putative receptor protein kinase CRINKLY4 precursor (EC| 2.7.11.1) Length = 901 Score = 80.9 bits (198), Expect = 1e-15 Identities = 45/107 (42%), Positives = 69/107 (64%), Gaps = 8/107 (7%) Frame = +1 Query: 139 LDWEARSAIALATARGVAHIHSTG-PTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPS 315 L+W R IA+ ARG+ ++H P H +IKSSN+L+ + + ARV+D GL +++GP+ Sbjct: 603 LNWARRVTIAVQAARGIEYLHGYACPPVIHRDIKSSNILIDEDHNARVADFGL-SILGPA 661 Query: 316 FSPTRVS-------GYRAPEVTDIRRVSQKADVYSFGVLLLELLTGK 435 S T +S GY PE + ++ K+DVYSFGV+LLE+L+G+ Sbjct: 662 DSGTPLSELPAGTLGYLDPEYYRLHYLTTKSDVYSFGVVLLEILSGR 708
>BAK1_ARATH (Q94F62) BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1| precursor (EC 2.7.11.1) (BRI1-associated receptor kinase 1) (Somatic embryogenesis receptor-like kinase 3) Length = 615 Score = 80.5 bits (197), Expect = 2e-15 Identities = 45/114 (39%), Positives = 67/114 (58%), Gaps = 8/114 (7%) Frame = +1 Query: 118 RSSGLTPLDWEARSAIALATARGVAHIHS-TGPTASHGNIKSSNVLLTKSYEARVSDHGL 294 R PLDW R IAL +ARG+A++H P H ++K++N+LL + +EA V D GL Sbjct: 378 RPESQPPLDWPKRQRIALGSARGLAYLHDHCDPKIIHRDVKAANILLDEEFEAVVGDFGL 437 Query: 295 PTLVGPSFSPTRVS-------GYRAPEVTDIRRVSQKADVYSFGVLLLELLTGK 435 L+ + T V+ G+ APE + S+K DV+ +GV+LLEL+TG+ Sbjct: 438 AKLM--DYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGVMLLELITGQ 489
>CLV1_ARATH (Q9SYQ8) Receptor protein kinase CLAVATA1 precursor (EC 2.7.11.1)| Length = 980 Score = 80.5 bits (197), Expect = 2e-15 Identities = 43/108 (39%), Positives = 63/108 (58%), Gaps = 7/108 (6%) Frame = +1 Query: 139 LDWEARSAIALATARGVAHIH-STGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPS 315 L WE R +A+ A+G+ ++H P H ++KS+N+LL +EA V+D GL + Sbjct: 786 LQWETRHRVAVEAAKGLCYLHHDCSPLILHRDVKSNNILLDSDFEAHVADFGLAKFLVDG 845 Query: 316 FSPTRVS------GYRAPEVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 + +S GY APE +V +K+DVYSFGV+LLEL+ GK P Sbjct: 846 AASECMSSIAGSYGYIAPEYAYTLKVDEKSDVYSFGVVLLELIAGKKP 893
>APK1A_ARATH (Q06548) Protein kinase APK1A, chloroplast precursor (EC 2.7.11.1)| Length = 410 Score = 80.5 bits (197), Expect = 2e-15 Identities = 45/107 (42%), Positives = 64/107 (59%), Gaps = 7/107 (6%) Frame = +1 Query: 136 PLDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPS 315 PL W+ R +AL A+G+A +HS+ + + K+SN+LL Y A++SD GL GP Sbjct: 172 PLSWKLRLKVALGAAKGLAFLHSSETRVIYRDFKTSNILLDSEYNAKLSDFGL-AKDGPI 230 Query: 316 FSPTRVS-------GYRAPEVTDIRRVSQKADVYSFGVLLLELLTGK 435 + VS GY APE ++ K+DVYSFGV+LLELL+G+ Sbjct: 231 GDKSHVSTRVMGTHGYAAPEYLATGHLTTKSDVYSFGVVLLELLSGR 277
>NORK_PEA (Q8LKZ1) Nodulation receptor kinase precursor (EC 2.7.11.1)| Length = 924 Score = 80.1 bits (196), Expect = 3e-15 Identities = 45/108 (41%), Positives = 69/108 (63%), Gaps = 7/108 (6%) Frame = +1 Query: 139 LDWEARSAIALATARGVAHIHS-TGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLV--- 306 LDW R +IAL ARG+A++H+ G + H ++KSSN+LL S A+V+D G Sbjct: 690 LDWPTRLSIALGAARGLAYLHTFPGRSVIHRDVKSSNILLDHSMCAKVADFGFSKYAPQE 749 Query: 307 GPSFSPTRV---SGYRAPEVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 G S+ V +GY PE +++S+K+DV+SFGV+LLE+++G+ P Sbjct: 750 GDSYVSLEVRGTAGYLDPEYYKTQQLSEKSDVFSFGVVLLEIVSGREP 797
>APK1B_ARATH (P46573) Protein kinase APK1B, chloroplast precursor (EC 2.7.11.1)| Length = 412 Score = 79.7 bits (195), Expect = 3e-15 Identities = 44/113 (38%), Positives = 66/113 (58%), Gaps = 7/113 (6%) Frame = +1 Query: 118 RSSGLTPLDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLP 297 R S PL W R +AL A+G+A +H+ + + + K+SN+LL Y A++SD GL Sbjct: 167 RGSYFQPLSWTLRLKVALGAAKGLAFLHNAETSVIYRDFKTSNILLDSEYNAKLSDFGL- 225 Query: 298 TLVGPSFSPTRVS-------GYRAPEVTDIRRVSQKADVYSFGVLLLELLTGK 435 GP+ + VS GY APE ++ K+DVYS+GV+LLE+L+G+ Sbjct: 226 AKDGPTGDKSHVSTRIMGTYGYAAPEYLATGHLTTKSDVYSYGVVLLEVLSGR 278
>PSKR_DAUCA (Q8LPB4) Phytosulfokine receptor precursor (EC 2.7.11.1)| (Phytosulfokine LRR receptor kinase) Length = 1021 Score = 79.3 bits (194), Expect = 4e-15 Identities = 47/111 (42%), Positives = 63/111 (56%), Gaps = 6/111 (5%) Frame = +1 Query: 127 GLTPLDWEARSAIALATARGVAHIH-STGPTASHGNIKSSNVLLTKSYEARVSDHGLPTL 303 G LDW+ R IA A G+A++H S P H +IKSSN+LL+ ++ A ++D GL L Sbjct: 834 GPPSLDWKTRLRIARGAAEGLAYLHQSCEPHILHRDIKSSNILLSDTFVAHLADFGLARL 893 Query: 304 VGPSFSPTRVS-----GYRAPEVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 + P + GY PE + K DVYSFGV+LLELLTG+ P Sbjct: 894 ILPYDTHVTTDLVGTLGYIPPEYGQASVATYKGDVYSFGVVLLELLTGRRP 944
>BRL2_ARATH (Q9ZPS9) Serine/threonine-protein kinase BRI1-like 2 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 2) (Protein VASCULAR HIGHWAY 1) Length = 1143 Score = 77.8 bits (190), Expect = 1e-14 Identities = 47/109 (43%), Positives = 61/109 (55%), Gaps = 7/109 (6%) Frame = +1 Query: 139 LDWEARSAIALATARGVAHIHSTG-PTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPS 315 L WE R IA A+G+ +H P H ++KSSNVLL + EARVSD G+ L+ Sbjct: 935 LGWEERKKIAKGAAKGLCFLHHNCIPHIIHRDMKSSNVLLDQDMEARVSDFGMARLISAL 994 Query: 316 FSPTRVS------GYRAPEVTDIRRVSQKADVYSFGVLLLELLTGKAPT 444 + VS GY PE R + K DVYS GV++LE+L+GK PT Sbjct: 995 DTHLSVSTLAGTPGYVPPEYYQSFRCTAKGDVYSIGVVMLEILSGKRPT 1043
>KPRO_MAIZE (P17801) Putative receptor protein kinase ZmPK1 precursor (EC| 2.7.11.1) Length = 817 Score = 76.6 bits (187), Expect = 3e-14 Identities = 44/105 (41%), Positives = 62/105 (59%), Gaps = 7/105 (6%) Frame = +1 Query: 139 LDWEARSAIALATARGVAHIHSTG-PTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPS 315 LDWE R IAL A+G+A++H H ++K N+LL +++E +++D GL L+ Sbjct: 627 LDWEGRFNIALGVAKGLAYLHHECLEWVIHCDVKPENILLDQAFEPKITDFGLVKLLNRG 686 Query: 316 FSPTRVS------GYRAPEVTDIRRVSQKADVYSFGVLLLELLTG 432 S VS GY APE ++ K DVYS+GV+LLELLTG Sbjct: 687 GSTQNVSHVRGTLGYIAPEWVSSLPITAKVDVYSYGVVLLELLTG 731
>KPEL_DROME (Q05652) Probable serine/threonine-protein kinase pelle (EC| 2.7.11.1) Length = 501 Score = 76.3 bits (186), Expect = 4e-14 Identities = 46/130 (35%), Positives = 70/130 (53%), Gaps = 8/130 (6%) Frame = +1 Query: 88 SCRRRVLAGNRSSGLTPLDWEARSAIALATARGVAHIHST-GPTASHGNIKSSNVLLTKS 264 S R+ A + L L W+ R +I+L TARG+ +H+ G HG+IK +N+LL + Sbjct: 298 SLEARLRAHKAQNPLPALTWQQRFSISLGTARGIYFLHTARGTPLIHGDIKPANILLDQC 357 Query: 265 YEARVSDHGL----PTLVGPSFSPTRVSG---YRAPEVTDIRRVSQKADVYSFGVLLLEL 423 + ++ D GL P + +V G Y PE + R++S DVYSFG++LLE+ Sbjct: 358 LQPKIGDFGLVREGPKSLDAVVEVNKVFGTKIYLPPEFRNFRQLSTGVDVYSFGIVLLEV 417 Query: 424 LTGKAPTHAV 453 TG+ T V Sbjct: 418 FTGRQVTDRV 427
>CX32_ARATH (P27450) Probable serine/threonine-protein kinase Cx32, chloroplast| precursor (EC 2.7.11.1) Length = 419 Score = 75.9 bits (185), Expect = 5e-14 Identities = 41/106 (38%), Positives = 63/106 (59%), Gaps = 7/106 (6%) Frame = +1 Query: 136 PLDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPS 315 P W+ R I + ARG+A +HS + + K+SN+LL +Y+A++SD GL L GP+ Sbjct: 187 PFPWDLRIKIVIGAARGLAFLHSLQREVIYRDFKASNILLDSNYDAKLSDFGLAKL-GPA 245 Query: 316 FSPTRVS-------GYRAPEVTDIRRVSQKADVYSFGVLLLELLTG 432 + V+ GY APE + K+DV++FGV+LLE++TG Sbjct: 246 DEKSHVTTRIMGTYGYAAPEYMATGHLYVKSDVFAFGVVLLEIMTG 291
>PSKR_ARATH (Q9ZVR7) Putative phytosulfokine receptor precursor (EC 2.7.11.1)| (Phytosulfokine LRR receptor kinase) Length = 1008 Score = 75.9 bits (185), Expect = 5e-14 Identities = 47/116 (40%), Positives = 64/116 (55%), Gaps = 8/116 (6%) Frame = +1 Query: 118 RSSGLTPLDWEARSAIALATARGVAHIHS-TGPTASHGNIKSSNVLLTKSYEARVSDHGL 294 R+ G L W+ R IA A+G+ ++H P H +IKSSN+LL +++ + ++D GL Sbjct: 822 RNDGPALLKWKTRLRIAQGAAKGLLYLHEGCDPHILHRDIKSSNILLDENFNSHLADFGL 881 Query: 295 PTLVGPSFSPTRVS-------GYRAPEVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 L+ P T VS GY PE + K DVYSFGV+LLELLT K P Sbjct: 882 ARLMSPY--ETHVSTDLVGTLGYIPPEYGQASVATYKGDVYSFGVVLLELLTDKRP 935
>RPK1_IPONI (P93194) Receptor-like protein kinase precursor (EC 2.7.11.1)| Length = 1109 Score = 75.9 bits (185), Expect = 5e-14 Identities = 44/107 (41%), Positives = 60/107 (56%), Gaps = 7/107 (6%) Frame = +1 Query: 136 PLDWEARSAIALATARGVAHIH-STGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVG- 309 PLDW R IA+ TA G+A++H P H +IK N+LL E +SD G+ L+ Sbjct: 910 PLDWSTRHNIAVGTAHGLAYLHFDCDPAIVHRDIKPMNILLDSDLEPHISDFGIAKLLDQ 969 Query: 310 -----PSFSPTRVSGYRAPEVTDIRRVSQKADVYSFGVLLLELLTGK 435 PS + GY APE S+++DVYS+GV+LLEL+T K Sbjct: 970 SATSIPSNTVQGTIGYMAPENAFTTVKSRESDVYSYGVVLLELITRK 1016
>PBS1_ARATH (Q9FE20) Serine/threonine-protein kinase PBS1 (EC 2.7.11.1)| (AvrPphB susceptible protein 1) Length = 456 Score = 74.3 bits (181), Expect = 1e-13 Identities = 43/107 (40%), Positives = 62/107 (57%), Gaps = 8/107 (7%) Frame = +1 Query: 139 LDWEARSAIALATARGVAHIHS-TGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPS 315 LDW R IA A+G+ +H P + + KSSN+LL + + ++SD GL L GP+ Sbjct: 182 LDWNMRMKIAAGAAKGLEFLHDKANPPVIYRDFKSSNILLDEGFHPKLSDFGLAKL-GPT 240 Query: 316 FSPTRVS-------GYRAPEVTDIRRVSQKADVYSFGVLLLELLTGK 435 + VS GY APE +++ K+DVYSFGV+ LEL+TG+ Sbjct: 241 GDKSHVSTRVMGTYGYCAPEYAMTGQLTVKSDVYSFGVVFLELITGR 287
>IRAK4_MOUSE (Q8R4K2) Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1)| (IRAK-4) Length = 459 Score = 72.8 bits (177), Expect = 4e-13 Identities = 43/110 (39%), Positives = 62/110 (56%), Gaps = 6/110 (5%) Frame = +1 Query: 127 GLTPLDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTL- 303 G PL W R +A TA G+ +H H +IKS+N+LL K + A++SD GL Sbjct: 279 GTPPLSWHTRCKVAQGTANGIRFLHENHHI--HRDIKSANILLDKDFTAKISDFGLARAS 336 Query: 304 --VGPSFSPTRVSG---YRAPEVTDIRRVSQKADVYSFGVLLLELLTGKA 438 + + +R+ G Y APE ++ K+D+YSFGV+LLEL+TG A Sbjct: 337 ARLAQTVMTSRIVGTTAYMAPEALR-GEITPKSDIYSFGVVLLELITGLA 385
>SIRK_ARATH (O64483) Senescence-induced receptor-like serine/threonine-protein| kinase precursor (FLG22-induced receptor-like kinase 1) Length = 876 Score = 70.5 bits (171), Expect = 2e-12 Identities = 44/117 (37%), Positives = 72/117 (61%), Gaps = 7/117 (5%) Frame = +1 Query: 106 LAGNRSSGLTPLDWEARSAIALATARGVAHIHS-TGPTASHGNIKSSNVLLTKSYEARVS 282 LAG RS L+ WE R I+L A+G+ ++H+ P H ++K +N+LL + +A+++ Sbjct: 658 LAGKRSFILS---WEERLKISLDAAQGLEYLHNGCKPPIVHRDVKPTNILLNEKLQAKMA 714 Query: 283 DHGLP---TLVGPSFSPTRVSG---YRAPEVTDIRRVSQKADVYSFGVLLLELLTGK 435 D GL ++ G T V+G Y PE R++++K+DVYS GV+LLE++TG+ Sbjct: 715 DFGLSRSFSVEGSGQISTVVAGSIGYLDPEYYSTRQMNEKSDVYSLGVVLLEVITGQ 771
>CTR1_ARATH (Q05609) Serine/threonine-protein kinase CTR1 (EC 2.7.11.1)| Length = 821 Score = 68.9 bits (167), Expect = 6e-12 Identities = 39/113 (34%), Positives = 63/113 (55%), Gaps = 4/113 (3%) Frame = +1 Query: 115 NRSSGLTPLDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGL 294 ++S LD R ++A A+G+ ++H+ P H ++KS N+L+ K Y +V D GL Sbjct: 638 HKSGAREQLDERRRLSMAYDVAKGMNYLHNRNPPIVHRDLKSPNLLVDKKYTVKVCDFGL 697 Query: 295 PTLVGPSFSPTRVSG----YRAPEVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 L +F ++ + + APEV ++K+DVYSFGV+L EL T + P Sbjct: 698 SRLKASTFLSSKSAAGTPEWMAPEVLRDEPSNEKSDVYSFGVILWELATLQQP 750
>IRAK4_HUMAN (Q9NWZ3) Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1)| (IRAK-4) (NY-REN-64 antigen) Length = 460 Score = 67.4 bits (163), Expect = 2e-11 Identities = 42/109 (38%), Positives = 61/109 (55%), Gaps = 7/109 (6%) Frame = +1 Query: 127 GLTPLDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLV 306 G PL W R IA A G+ +H H +IKS+N+LL +++ A++SD GL Sbjct: 279 GTPPLSWHMRCKIAQGAANGINFLHENHHI--HRDIKSANILLDEAFTAKISDFGLAR-A 335 Query: 307 GPSFSPT----RVSG---YRAPEVTDIRRVSQKADVYSFGVLLLELLTG 432 F+ T R+ G Y APE ++ K+D+YSFGV+LLE++TG Sbjct: 336 SEKFAQTVMTSRIVGTTAYMAPEALR-GEITPKSDIYSFGVVLLEIITG 383
>IRAK3_MOUSE (Q8K4B2) Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1)| (IRAK-3) (IL-1 receptor-associated kinase M) (IRAK-M) Length = 609 Score = 66.2 bits (160), Expect = 4e-11 Identities = 38/115 (33%), Positives = 62/115 (53%), Gaps = 11/115 (9%) Frame = +1 Query: 121 SSGLTPLDWEARSAIALATARGVAHIHSTGPTASH-GNIKSSNVLLTKSYEARVSD---- 285 ++G TPL W R ++ + A+ + ++H+T P A GN+ S+N+LL + +++D Sbjct: 269 TNGTTPLSWHVRISVLIGIAKAIQYLHNTQPCAVICGNVSSANILLDDQLQPKLTDFAAA 328 Query: 286 HGLPTLVGPSFSPTRVSG------YRAPEVTDIRRVSQKADVYSFGVLLLELLTG 432 H P L S + G Y E R+S K DVYSFG++++E+LTG Sbjct: 329 HFRPNLEQQSSTINMTGGGRKHLWYMPEEYIRQGRLSVKTDVYSFGIVIMEVLTG 383
>YR831_MIMIV (Q7T6Y2) Putative serine/threonine-protein kinase/receptor R831| precursor (EC 2.7.11.1) Length = 1624 Score = 65.1 bits (157), Expect = 8e-11 Identities = 32/90 (35%), Positives = 55/90 (61%), Gaps = 2/90 (2%) Frame = +1 Query: 178 ARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPSFSPTRVSG--YRAP 351 A G+ ++HS+ P H +IK +N+L+ + + +++D G + + + TR + AP Sbjct: 1470 AMGIDYLHSSNPMIVHRDIKPANILVDEHFNVKIADFGFARIKEDNTTMTRCGTPCWTAP 1529 Query: 352 EVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 EV + +KADV+SFGV++ E+LTGK P Sbjct: 1530 EVIRGEKYCEKADVFSFGVVMWEVLTGKEP 1559 Score = 47.4 bits (111), Expect = 2e-05 Identities = 36/102 (35%), Positives = 54/102 (52%), Gaps = 9/102 (8%) Frame = +1 Query: 163 IALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPSFSPTRVSG- 339 +A ++G+ +HS+G H ++KS N+LL + +VSD GL T V + + Sbjct: 888 MAYQASKGMHFLHSSGIV--HRDLKSLNLLLDSKWNVKVSDFGL-TKVKSELDKKKTNDN 944 Query: 340 ------YRAPEV-TDIRRVSQ-KADVYSFGVLLLELLTGKAP 441 + APE+ D V ADVYSFG++L ELLT + P Sbjct: 945 IIGTIHWIAPEILNDSTEVDYILADVYSFGIILWELLTREQP 986
>IRAK1_MOUSE (Q62406) Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1)| (IRAK-1) (IRAK) (Pelle-like protein kinase) (mPLK) Length = 710 Score = 62.8 bits (151), Expect = 4e-10 Identities = 39/119 (32%), Positives = 56/119 (47%), Gaps = 13/119 (10%) Frame = +1 Query: 118 RSSGLTPLDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLP 297 ++ +PL W R I L TAR + +H P+ HG+IKSSNVLL + ++ D GL Sbjct: 303 QTQACSPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLMPKLGDFGLA 362 Query: 298 TL-------VGPSFSPTRVS------GYRAPEVTDIRRVSQKADVYSFGVLLLELLTGK 435 S + R S Y E R++ D +SFGV++LE L G+ Sbjct: 363 RFSRFAGAKASQSSTVARTSTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVILETLAGQ 421
>IRAK1_HUMAN (P51617) Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1)| (IRAK-1) Length = 712 Score = 62.0 bits (149), Expect = 7e-10 Identities = 37/113 (32%), Positives = 54/113 (47%), Gaps = 13/113 (11%) Frame = +1 Query: 136 PLDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGL------- 294 PL W R I L TAR + +H P+ HG+IKSSNVLL + ++ D GL Sbjct: 309 PLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFA 368 Query: 295 ------PTLVGPSFSPTRVSGYRAPEVTDIRRVSQKADVYSFGVLLLELLTGK 435 ++V + + Y E R++ D +SFGV++LE L G+ Sbjct: 369 GSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQ 421
>RIPK3_RAT (Q9Z2P5) Receptor-interacting serine/threonine-protein kinase 3 (EC| 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) (Homocysteine respondent protein HCYP2) Length = 478 Score = 60.8 bits (146), Expect = 2e-09 Identities = 40/109 (36%), Positives = 58/109 (53%), Gaps = 9/109 (8%) Frame = +1 Query: 136 PLDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVG-- 309 P W + G+ ++HS P+ H ++K SNVLL A+++D GL T G Sbjct: 112 PRPWPLLCRLLEEVVLGMCYLHSLNPSLLHRDLKPSNVLLDLELHAKLADFGLSTFQGGS 171 Query: 310 --PSFSPTRVSG----YRAPEVTD-IRRVSQKADVYSFGVLLLELLTGK 435 S S +R SG Y APE+ D + S+ +DVYSFGVL+ +L G+ Sbjct: 172 QSGSGSGSRDSGGTLAYLAPELLDNDGKASKASDVYSFGVLVWTVLAGR 220
>SRK6_BRAOE (Q09092) Putative serine/threonine-protein kinase receptor| precursor (EC 2.7.11.1) (S-receptor kinase) (SRK) Length = 849 Score = 58.9 bits (141), Expect = 6e-09 Identities = 34/106 (32%), Positives = 56/106 (52%), Gaps = 7/106 (6%) Frame = +1 Query: 139 LDWEARSAIALATARGVAHIHSTGP-TASHGNIKSSNVLLTKSYEARVSDHGLPTLV--- 306 L+W R I ARG+ ++H H ++K SN+LL K+ ++SD G+ + Sbjct: 622 LNWNERFDITNGVARGLLYLHQDSRFRIIHRDLKVSNILLDKNMIPKISDFGMARIFERD 681 Query: 307 ---GPSFSPTRVSGYRAPEVTDIRRVSQKADVYSFGVLLLELLTGK 435 + GY +PE S+K+DV+SFGV++LE+++GK Sbjct: 682 ETEANTMKVVGTYGYMSPEYAMYGIFSEKSDVFSFGVIVLEIVSGK 727
>GUC2C_HUMAN (P25092) Heat-stable enterotoxin receptor precursor (GC-C)| (Intestinal guanylate cyclase) (EC 4.6.1.2) (STA receptor) (hSTAR) Length = 1073 Score = 58.9 bits (141), Expect = 6e-09 Identities = 30/101 (29%), Positives = 58/101 (57%) Frame = +1 Query: 133 TPLDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGP 312 T +DWE + ++ A+G++++HS+ T HG +KS+N ++ +++D G +++ Sbjct: 583 TFMDWEFKISVLYDIAKGMSYLHSS-KTEVHGRLKSTNCVVDSRMVVKITDFGCNSIL-- 639 Query: 313 SFSPTRVSGYRAPEVTDIRRVSQKADVYSFGVLLLELLTGK 435 P + + APE +SQK DVYS+G++ E++ K Sbjct: 640 ---PPKKDLWTAPEHLRQANISQKGDVYSYGIIAQEIILRK 677
>M3K10_HUMAN (Q02779) Mitogen-activated protein kinase kinase kinase 10 (EC| 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST) Length = 954 Score = 58.5 bits (140), Expect = 8e-09 Identities = 42/125 (33%), Positives = 65/125 (52%), Gaps = 11/125 (8%) Frame = +1 Query: 100 RVLAGNRSSGLTPLDWEARSAIALATARGVAHIHSTGPTAS-HGNIKSSNVLLTKSYE-- 270 RVLAG R ++W A+ ARG+ ++H+ P H ++KS N+L+ ++ E Sbjct: 184 RVLAGRRVPPHVLVNW------AVQVARGMNYLHNDAPVPIIHRDLKSINILILEAIENH 237 Query: 271 ------ARVSDHGLPTLVGPSFSPTRVSGYR--APEVTDIRRVSQKADVYSFGVLLLELL 426 +++D GL + + Y APEV + S+ +DV+SFGVLL ELL Sbjct: 238 NLADTVLKITDFGLAREWHKTTKMSAAGTYAWMAPEVIRLSLFSKSSDVWSFGVLLWELL 297 Query: 427 TGKAP 441 TG+ P Sbjct: 298 TGEVP 302
>GUC2C_PIG (P55204) Heat-stable enterotoxin receptor precursor (GC-C)| (Intestinal guanylate cyclase) (EC 4.6.1.2) (STA receptor) Length = 1073 Score = 58.5 bits (140), Expect = 8e-09 Identities = 30/98 (30%), Positives = 57/98 (58%) Frame = +1 Query: 133 TPLDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGP 312 T +DWE + ++ A+G++++HS+ T HG +KS+N ++ +++D G +++ P Sbjct: 583 TFMDWEFKISVLYDIAKGMSYLHSS-KTEVHGRLKSTNCVVDSRMVVKITDFGCNSILAP 641 Query: 313 SFSPTRVSGYRAPEVTDIRRVSQKADVYSFGVLLLELL 426 + + APE VSQK DVYS+G++ E++ Sbjct: 642 -----KKDLWTAPEHLRRASVSQKGDVYSYGIIAQEII 674
>RIPK3_HUMAN (Q9Y572) Receptor-interacting serine/threonine-protein kinase 3 (EC| 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) Length = 518 Score = 57.8 bits (138), Expect = 1e-08 Identities = 36/108 (33%), Positives = 51/108 (47%), Gaps = 8/108 (7%) Frame = +1 Query: 136 PLDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPS 315 P W + G+ ++H P H ++K SNVL +++D GL T G S Sbjct: 111 PRPWPLLCRLLKEVVLGMFYLHDQNPVLLHRDLKPSNVLPDPELHVKLADFGLSTFQGGS 170 Query: 316 FS------PTRVSGYRAPE--VTDIRRVSQKADVYSFGVLLLELLTGK 435 S P GY APE V R+ S +DVYSFG+L+ +L G+ Sbjct: 171 QSGTGSGEPGGTLGYLAPELFVNVNRKASTASDVYSFGILMWAVLAGR 218
>M3K13_HUMAN (O43283) Mitogen-activated protein kinase kinase kinase 13 (EC| 2.7.11.25) (Mixed lineage kinase) (MLK) (Leucine zipper-bearing kinase) Length = 966 Score = 57.8 bits (138), Expect = 1e-08 Identities = 37/114 (32%), Positives = 58/114 (50%), Gaps = 3/114 (2%) Frame = +1 Query: 109 AGNRSSGLTPLDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDH 288 AG + + +DW +A+ H+H H ++KS NVL+T + ++SD Sbjct: 247 AGRKITPRLLVDWST----GIASGMNYLHLHKI----IHRDLKSPNVLVTHTDAVKISDF 298 Query: 289 GLPTLVGPSFSPTRVSG---YRAPEVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 G + + +G + APEV VS+K D++SFGV+L ELLTG+ P Sbjct: 299 GTSKELSDKSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIP 352
>M3K13_PONPY (Q5R8X7) Mitogen-activated protein kinase kinase kinase 13 (EC| 2.7.11.25) Length = 966 Score = 57.4 bits (137), Expect = 2e-08 Identities = 37/114 (32%), Positives = 58/114 (50%), Gaps = 3/114 (2%) Frame = +1 Query: 109 AGNRSSGLTPLDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDH 288 AG + + +DW +A+ H+H H ++KS NVL+T + ++SD Sbjct: 247 AGRKITPRLLVDWST----GIASGMNYLHLHKI----IHRDLKSPNVLVTHTDAVKISDF 298 Query: 289 GLPTLVGPSFSPTRVSG---YRAPEVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 G + + +G + APEV VS+K D++SFGV+L ELLTG+ P Sbjct: 299 GTSKELSDKSTKMSFAGTVAWLAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIP 352
>RIPK2_MOUSE (P58801) Receptor-interacting serine/threonine-protein kinase 2 (EC| 2.7.11.1) Length = 539 Score = 55.8 bits (133), Expect = 5e-08 Identities = 38/128 (29%), Positives = 59/128 (46%), Gaps = 13/128 (10%) Frame = +1 Query: 115 NRSSGLTPLDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGL 294 +R + + W R I A GV ++H+ P H ++K+ N+LL + +++D GL Sbjct: 108 HRKTEYPDIAWPLRFRILHEIALGVNYLHNMNPPLLHHDLKTQNILLDNEFHVKIADFGL 167 Query: 295 PTLVGPSFSPTRVSGYRAPEVTDI-------------RRVSQKADVYSFGVLLLELLTGK 435 S S +R S APE I R S K D+YS+ V++ E+L+ K Sbjct: 168 SKWRMMSLSQSR-SYKSAPEGGTIIYMPPENYEPGQKSRASVKHDIYSYAVIMWEVLSRK 226 Query: 436 APTHAVVN 459 P V N Sbjct: 227 QPFEEVTN 234
>M3LK7_DROME (P83104) Putative mitogen-activated protein kinase kinase kinase| 7-like (EC 2.7.11.25) Length = 393 Score = 55.8 bits (133), Expect = 5e-08 Identities = 36/96 (37%), Positives = 54/96 (56%), Gaps = 4/96 (4%) Frame = +1 Query: 166 ALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYE-ARVSDHGLPTLVGPSFSPTRVSG- 339 AL A+ +A++HS H +IK N+LL +E ++ D GL T + S + T + G Sbjct: 112 ALQCAKALAYLHSLDRPIVHRDIKPQNMLLYNQHEDLKICDFGLATDM--SNNKTDMQGT 169 Query: 340 --YRAPEVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 Y APE + + K DVYSFG++L EL+T + P Sbjct: 170 LRYMAPEAIKHLKYTAKCDVYSFGIMLWELMTRQLP 205
>GCY1_CAEEL (Q09435) Guanylate cyclase receptor-type gcy-1 precursor (EC| 4.6.1.2) Length = 1137 Score = 55.8 bits (133), Expect = 5e-08 Identities = 34/119 (28%), Positives = 61/119 (51%), Gaps = 4/119 (3%) Frame = +1 Query: 91 CRRRVLAGNRSSGLTPLDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYE 270 C R L S G +D+ I A+G+ ++H T HGN++S+ L+ S++ Sbjct: 639 CSRGSLQDILSRGNFSMDYFFMFCIIRDVAKGLEYLHKTF-LRLHGNLRSATCLVNDSWQ 697 Query: 271 ARVSDHGLPTLVGPSFSPTRVSGYRAPEVT----DIRRVSQKADVYSFGVLLLELLTGK 435 +++++G+ LV P + + APEV + ++ AD+YSF ++ E+LT K Sbjct: 698 VKLAEYGMDNLVEEQTPPKKRLLWVAPEVLRGSLSVSQMEPSADIYSFAIIASEILTKK 756
>OXSR1_PONPY (Q5R495) Serine/threonine-protein kinase OSR1 (EC 2.7.11.1)| (Oxidative stress-responsive 1 protein) Length = 527 Score = 54.7 bits (130), Expect = 1e-07 Identities = 37/125 (29%), Positives = 59/125 (47%), Gaps = 10/125 (8%) Frame = +1 Query: 103 VLAGNRSSGLTPLDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVS 282 V G SG+ LD + I G+ ++H G H ++K+ N+LL + +++ Sbjct: 108 VAKGEHKSGV--LDESTIATILREVLEGLEYLHKNGQI--HRDVKAGNILLGEDGSVQIA 163 Query: 283 DHGLPTLVGPSFSPTR---------VSGYRAPEVTD-IRRVSQKADVYSFGVLLLELLTG 432 D G+ + TR + APEV + +R KAD++SFG+ +EL TG Sbjct: 164 DFGVSAFLATGGDITRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADIWSFGITAIELATG 223 Query: 433 KAPTH 447 AP H Sbjct: 224 AAPYH 228
>OXSR1_HUMAN (O95747) Serine/threonine-protein kinase OSR1 (EC 2.7.11.1)| (Oxidative stress-responsive 1 protein) Length = 527 Score = 54.7 bits (130), Expect = 1e-07 Identities = 37/125 (29%), Positives = 59/125 (47%), Gaps = 10/125 (8%) Frame = +1 Query: 103 VLAGNRSSGLTPLDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVS 282 V G SG+ LD + I G+ ++H G H ++K+ N+LL + +++ Sbjct: 108 VAKGEHKSGV--LDESTIATILREVLEGLEYLHKNGQI--HRDVKAGNILLGEDGSVQIA 163 Query: 283 DHGLPTLVGPSFSPTR---------VSGYRAPEVTD-IRRVSQKADVYSFGVLLLELLTG 432 D G+ + TR + APEV + +R KAD++SFG+ +EL TG Sbjct: 164 DFGVSAFLATGGDITRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADIWSFGITAIELATG 223 Query: 433 KAPTH 447 AP H Sbjct: 224 AAPYH 228
>TESK1_HUMAN (Q15569) Dual specificity testis-specific protein kinase 1 (EC| 2.7.12.1) (Testicular protein kinase 1) Length = 626 Score = 54.7 bits (130), Expect = 1e-07 Identities = 38/108 (35%), Positives = 55/108 (50%), Gaps = 11/108 (10%) Frame = +1 Query: 136 PLDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKS---YEARVSDHGLPTLV 306 PL W R +AL ARG+ ++HS G H ++ S N L+ + + A V D GL + Sbjct: 146 PLSWPVRLHLALDIARGLRYLHSKG--VFHRDLTSKNCLVRREDRGFTAVVGDFGLAEKI 203 Query: 307 -----GPSFSPTRVSG---YRAPEVTDIRRVSQKADVYSFGVLLLELL 426 G P V G + APEV +KADV++FG++L EL+ Sbjct: 204 PVYREGARKEPLAVVGSPYWMAPEVLRGELYDEKADVFAFGIVLCELI 251
>OXSR1_MOUSE (Q6P9R2) Serine/threonine-protein kinase OSR1 (EC 2.7.11.1)| (Oxidative stress-responsive 1 protein) Length = 527 Score = 54.3 bits (129), Expect = 1e-07 Identities = 37/125 (29%), Positives = 59/125 (47%), Gaps = 10/125 (8%) Frame = +1 Query: 103 VLAGNRSSGLTPLDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVS 282 V G SG+ LD + I G+ ++H G H ++K+ N+LL + +++ Sbjct: 108 VAKGEHKSGV--LDEPTIATILREVLEGLEYLHKNGQI--HRDVKAGNILLGEDGSVQIA 163 Query: 283 DHGLPTLVGPSFSPTR---------VSGYRAPEVTD-IRRVSQKADVYSFGVLLLELLTG 432 D G+ + TR + APEV + +R KAD++SFG+ +EL TG Sbjct: 164 DFGVSAFLATGGDITRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADIWSFGITAIELATG 223 Query: 433 KAPTH 447 AP H Sbjct: 224 AAPYH 228
>RIPK4_HUMAN (P57078) Receptor-interacting serine/threonine-protein kinase 4 (EC| 2.7.11.1) (Ankyrin repeat domain protein 3) (PKC-delta-interacting protein kinase) Length = 832 Score = 54.3 bits (129), Expect = 1e-07 Identities = 39/113 (34%), Positives = 53/113 (46%), Gaps = 11/113 (9%) Frame = +1 Query: 136 PLDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPS 315 PL W+ R I TA G+ +H P H ++K +N+LL Y ++SD GL G S Sbjct: 112 PLPWDLRFRIIHETAVGMNFLHCMAPPLLHLDLKPANILLDAHYHVKISDFGLAKCNGLS 171 Query: 316 FSPT-------RVSGYRAPEVTDIRRVSQ----KADVYSFGVLLLELLTGKAP 441 S Y PE IR S+ K DVYSF +++ +LT K P Sbjct: 172 HSHDLSMDGLFGTIAYLPPE--RIREKSRLFDTKHDVYSFAIVIWGVLTQKKP 222
>M3K12_RAT (Q63796) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 888 Score = 54.3 bits (129), Expect = 1e-07 Identities = 34/104 (32%), Positives = 54/104 (51%), Gaps = 3/104 (2%) Frame = +1 Query: 139 LDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPSF 318 +DW ++ +A H+H H ++KS N+L+T ++SD G + Sbjct: 247 VDW----SMGIAGGMNYLHLHKI----IHRDLKSPNMLITYDDVVKISDFGTSKELSDKS 298 Query: 319 SPTRVSG---YRAPEVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 + +G + APEV VS+K D++SFGV+L ELLTG+ P Sbjct: 299 TKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIP 342
>M3K12_MOUSE (Q60700) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 888 Score = 54.3 bits (129), Expect = 1e-07 Identities = 34/104 (32%), Positives = 54/104 (51%), Gaps = 3/104 (2%) Frame = +1 Query: 139 LDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPSF 318 +DW ++ +A H+H H ++KS N+L+T ++SD G + Sbjct: 247 VDW----SMGIAGGMNYLHLHKI----IHRDLKSPNMLITYDDVVKISDFGTSKELSDKS 298 Query: 319 SPTRVSG---YRAPEVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 + +G + APEV VS+K D++SFGV+L ELLTG+ P Sbjct: 299 TKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIP 342
>GUC2C_RAT (P23897) Heat-stable enterotoxin receptor precursor (GC-C)| (Intestinal guanylate cyclase) (EC 4.6.1.2) (STA receptor) Length = 1072 Score = 54.3 bits (129), Expect = 1e-07 Identities = 29/101 (28%), Positives = 56/101 (55%) Frame = +1 Query: 133 TPLDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGP 312 T +DWE + ++ A+G++++HS+ HG +KS+N ++ +++D G +++ Sbjct: 582 TFMDWEFKISVLNDIAKGMSYLHSS-KIEVHGRLKSTNCVVDSRMVVKITDFGCNSIL-- 638 Query: 313 SFSPTRVSGYRAPEVTDIRRVSQKADVYSFGVLLLELLTGK 435 P + + APE +SQK DVYSF ++ E++ K Sbjct: 639 ---PPKKDLWTAPEHLRQATISQKGDVYSFSIIAQEIILRK 676
>OXSR1_PIG (Q863I2) Serine/threonine-protein kinase OSR1 (EC 2.7.11.1)| (Oxidative stress-responsive 1 protein) Length = 529 Score = 54.3 bits (129), Expect = 1e-07 Identities = 37/125 (29%), Positives = 59/125 (47%), Gaps = 10/125 (8%) Frame = +1 Query: 103 VLAGNRSSGLTPLDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVS 282 V G SG+ LD + I G+ ++H G H ++K+ N+LL + +++ Sbjct: 108 VAKGEHKSGV--LDEATIATILREVLEGLEYLHKNGQI--HRDVKAGNILLGEDGSVQIA 163 Query: 283 DHGLPTLVGPSFSPTR---------VSGYRAPEVTD-IRRVSQKADVYSFGVLLLELLTG 432 D G+ + TR + APEV + +R KAD++SFG+ +EL TG Sbjct: 164 DFGVSAFLATGGDITRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADIWSFGITAIELATG 223 Query: 433 KAPTH 447 AP H Sbjct: 224 AAPYH 228
>M3K12_HUMAN (Q12852) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 859 Score = 54.3 bits (129), Expect = 1e-07 Identities = 34/104 (32%), Positives = 54/104 (51%), Gaps = 3/104 (2%) Frame = +1 Query: 139 LDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPSF 318 +DW ++ +A H+H H ++KS N+L+T ++SD G + Sbjct: 214 VDW----SMGIAGGMNYLHLHKI----IHRDLKSPNMLITYDDVVKISDFGTSKELSDKS 265 Query: 319 SPTRVSG---YRAPEVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 + +G + APEV VS+K D++SFGV+L ELLTG+ P Sbjct: 266 TKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIP 309
>M3KSL_DROME (Q95UN8) Mitogen-activated protein kinase kinase kinase (EC| 2.7.11.25) (Mixed lineage kinase) (dMLK) (Protein slipper) Length = 1161 Score = 53.9 bits (128), Expect = 2e-07 Identities = 34/103 (33%), Positives = 58/103 (56%), Gaps = 11/103 (10%) Frame = +1 Query: 166 ALATARGVAHIHSTGPTAS-HGNIKSSNVLLTKSYEA--------RVSDHGLPTLVGPS- 315 A+ ARG+ ++H+ P + H ++KSSNVL+ ++ E +++D GL + + Sbjct: 242 AIQIARGMNYLHNEAPMSIIHRDLKSSNVLIYEAIEGNHLQQKTLKITDFGLAREMYNTQ 301 Query: 316 -FSPTRVSGYRAPEVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 S + PEV + S+ +DV+S+GVLL EL+TG+ P Sbjct: 302 RMSAAGTYAWMPPEVISVSTYSKFSDVWSYGVLLWELITGETP 344
>RIPK2_HUMAN (O43353) Receptor-interacting serine/threonine-protein kinase 2 (EC| 2.7.11.1) (RIP-like-interacting CLARP kinase) (Receptor-interacting protein 2) (RIP-2) (CARD-containing interleukin-1 beta-converting enzyme-associated kinase) (CARD-containi Length = 540 Score = 53.9 bits (128), Expect = 2e-07 Identities = 38/128 (29%), Positives = 58/128 (45%), Gaps = 13/128 (10%) Frame = +1 Query: 115 NRSSGLTPLDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGL 294 +R + + W R I A GV ++H+ P H ++K+ N+LL + +++D GL Sbjct: 108 HRKTEYPDVAWPLRFRILHEIALGVNYLHNMTPPLLHHDLKTQNILLDNEFHVKIADFGL 167 Query: 295 PTLVGPSFSPTRVSGYRAPEVTDI-------------RRVSQKADVYSFGVLLLELLTGK 435 S S +R S APE I R S K D+YS+ V+ E+L+ K Sbjct: 168 SKWRMMSLSQSR-SSKSAPEGGTIIYMPPENYEPGQKSRASIKHDIYSYAVITWEVLSRK 226 Query: 436 APTHAVVN 459 P V N Sbjct: 227 QPFEDVTN 234
>ANPRA_RAT (P18910) Atrial natriuretic peptide receptor A precursor (ANP-A)| (ANPRA) (GC-A) (Guanylate cyclase) (EC 4.6.1.2) (NPR-A) (Atrial natriuretic peptide A-type receptor) Length = 1057 Score = 53.5 bits (127), Expect = 3e-07 Identities = 33/103 (32%), Positives = 54/103 (52%), Gaps = 8/103 (7%) Frame = +1 Query: 139 LDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPSF 318 LDW R ++ +G+ +H+ G SHGN+KSSN ++ + +++D+GL + P Sbjct: 627 LDWMFRYSLTNDIVKGMLFLHN-GAICSHGNLKSSNCVVDGRFVLKITDYGLESFRDPEP 685 Query: 319 SPTRV----SGYRAPEVTDI----RRVSQKADVYSFGVLLLEL 423 + APE+ + R SQ DVYSFG++L E+ Sbjct: 686 EQGHTLFAKKLWTAPELLRMASPPARGSQAGDVYSFGIILQEI 728
>ANPRA_MOUSE (P18293) Atrial natriuretic peptide receptor A precursor (ANP-A)| (ANPRA) (GC-A) (Guanylate cyclase) (EC 4.6.1.2) (NPR-A) (Atrial natriuretic peptide A-type receptor) Length = 1057 Score = 53.5 bits (127), Expect = 3e-07 Identities = 33/103 (32%), Positives = 54/103 (52%), Gaps = 8/103 (7%) Frame = +1 Query: 139 LDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPSF 318 LDW R ++ +G+ +H+ G SHGN+KSSN ++ + +++D+GL + P Sbjct: 627 LDWMFRYSLTNDIVKGMLFLHN-GAIGSHGNLKSSNCVVDGRFVLKITDYGLESFRDPEP 685 Query: 319 SPTRV----SGYRAPEVTDI----RRVSQKADVYSFGVLLLEL 423 + APE+ + R SQ DVYSFG++L E+ Sbjct: 686 EQGHTLFAKKLWTAPELLRMASPPARGSQAGDVYSFGIILQEI 728
>TNI3K_RAT (Q7TQP6) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 834 Score = 53.5 bits (127), Expect = 3e-07 Identities = 37/107 (34%), Positives = 59/107 (55%), Gaps = 6/107 (5%) Frame = +1 Query: 139 LDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVG--P 312 LD +++ IA+ A+G+ ++HS H ++ S N+LL + A V+D G + Sbjct: 557 LDLQSKLIIAVDVAKGMEYLHSLTQPIIHRDLNSHNILLYEDGHAVVADFGESRFLQSLD 616 Query: 313 SFSPTRVSG---YRAPEV-TDIRRVSQKADVYSFGVLLLELLTGKAP 441 + T+ G + APEV T R + KADV+S+ + L ELLTG+ P Sbjct: 617 EDNMTKQPGNLRWMAPEVFTQCTRYTIKADVFSYSLCLWELLTGEIP 663
>HT1_ARATH (Q2MHE4) Serine/threonine-protein kinase HT1 (EC 2.7.11.1) (High| leaf temperature protein 1) Length = 390 Score = 53.5 bits (127), Expect = 3e-07 Identities = 33/96 (34%), Positives = 52/96 (54%), Gaps = 3/96 (3%) Frame = +1 Query: 163 IALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHG---LPTLVGPSFSPTRV 333 +AL +RG+ ++HS G H ++KS+N+LL +V+D G L T + Sbjct: 192 LALDISRGMEYLHSQG--VIHRDLKSNNLLLNDEMRVKVADFGTSCLETQCREAKGNMGT 249 Query: 334 SGYRAPEVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 + APE+ + ++K DVYSFG++L EL T P Sbjct: 250 YRWMAPEMIKEKPYTRKVDVYSFGIVLWELTTALLP 285
>M3K11_HUMAN (Q16584) Mitogen-activated protein kinase kinase kinase 11 (EC| 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline-rich kinase) Length = 847 Score = 53.5 bits (127), Expect = 3e-07 Identities = 41/129 (31%), Positives = 63/129 (48%), Gaps = 11/129 (8%) Frame = +1 Query: 100 RVLAGNRSSGLTPLDWEARSAIALATARGVAHIHSTGPT-ASHGNIKSSNVLLTKSYEA- 273 R LAG R ++W A+ ARG+ ++H H ++KS+N+LL + E+ Sbjct: 203 RALAGRRVPPHVLVNW------AVQIARGMHYLHCEALVPVIHRDLKSNNILLLQPIESD 256 Query: 274 -------RVSDHGLPTLVGPSFSPTRVSGYR--APEVTDIRRVSQKADVYSFGVLLLELL 426 +++D GL + + Y APEV S+ +DV+SFGVLL ELL Sbjct: 257 DMEHKTLKITDFGLAREWHKTTQMSAAGTYAWMAPEVIKASTFSKGSDVWSFGVLLWELL 316 Query: 427 TGKAPTHAV 453 TG+ P + Sbjct: 317 TGEVPYRGI 325
>GUC2C_CAVPO (P70106) Heat-stable enterotoxin receptor precursor (GC-C)| (Intestinal guanylate cyclase) (EC 4.6.1.2) (STA receptor) (Guanylyl cyclase C) Length = 1076 Score = 53.1 bits (126), Expect = 3e-07 Identities = 28/98 (28%), Positives = 54/98 (55%) Frame = +1 Query: 133 TPLDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGP 312 T + WE + ++ A+G++++HS+ HG +KS+N ++ +++D G +++ Sbjct: 586 TIMGWEFKISVLYDIAKGMSYLHSS-KIEVHGRLKSTNCVVDSRMVVKITDFGYNSIL-- 642 Query: 313 SFSPTRVSGYRAPEVTDIRRVSQKADVYSFGVLLLELL 426 P + + APE SQK DVYSFG++ E++ Sbjct: 643 ---PPKKDLWTAPEHLRQASTSQKGDVYSFGIIAQEII 677
>PKPA_PHYBL (Q01577) Serine/threonine-protein kinase pkpA (EC 2.7.11.1)| Length = 613 Score = 53.1 bits (126), Expect = 3e-07 Identities = 26/89 (29%), Positives = 51/89 (57%), Gaps = 2/89 (2%) Frame = +1 Query: 181 RGVAHIHSTGPTASHGNIKSSNVLLTKSY-EARVSDHGLPTLV-GPSFSPTRVSGYRAPE 354 +G+A++H P H +IK N+ + ++ E ++ D G + G ++ + APE Sbjct: 124 KGLAYLHGHEPPIIHRDIKCDNIFINGAHGEIKIGDMGTAEMKNGKKYTVIGTPEFMAPE 183 Query: 355 VTDIRRVSQKADVYSFGVLLLELLTGKAP 441 + + + ++K D+Y+FG+ LLE+ TG+ P Sbjct: 184 MYEEQGYNEKVDIYAFGMCLLEMATGEYP 212
>KYK2_DICDI (P18161) Tyrosine-protein kinase 2 (EC 2.7.10.2) (Fragment)| Length = 410 Score = 53.1 bits (126), Expect = 3e-07 Identities = 34/100 (34%), Positives = 54/100 (54%), Gaps = 7/100 (7%) Frame = +1 Query: 163 IALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPSFSPTRVSG- 339 +A A G+ H+HS T H ++ S N+LL + ++SD GL S T +G Sbjct: 212 MATDMALGLLHLHSI--TIVHRDLTSQNILLDELGNIKISDFGLSAEKSREGSMTMTNGG 269 Query: 340 -----YRAPEVT-DIRRVSQKADVYSFGVLLLELLTGKAP 441 +R PE+T ++ S+K DVY F +++ E+LTG+ P Sbjct: 270 ICNPRWRPPELTKNLGHYSEKVDVYCFSLVVWEILTGEIP 309
>ANPRA_HUMAN (P16066) Atrial natriuretic peptide receptor A precursor (ANP-A)| (ANPRA) (GC-A) (Guanylate cyclase) (EC 4.6.1.2) (NPR-A) (Atrial natriuretic peptide A-type receptor) Length = 1061 Score = 53.1 bits (126), Expect = 3e-07 Identities = 34/103 (33%), Positives = 57/103 (55%), Gaps = 8/103 (7%) Frame = +1 Query: 139 LDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTL--VGP 312 LDW R ++ +G+ +H+ G SHGN+KSSN ++ + +++D+GL + + P Sbjct: 631 LDWMFRYSLTNDIVKGMLFLHN-GAICSHGNLKSSNCVVDGRFVLKITDYGLESFRDLDP 689 Query: 313 SFSPTRVSG--YRAPEVTDIR----RVSQKADVYSFGVLLLEL 423 T + + APE+ + R SQ DVYSFG++L E+ Sbjct: 690 EQGHTVYAKKLWTAPELLRMASPPVRGSQAGDVYSFGIILQEI 732
>KYK1_DICDI (P18160) Non-receptor tyrosine kinase spore lysis A (EC 2.7.10.2)| (Tyrosine-protein kinase 1) Length = 1584 Score = 52.8 bits (125), Expect = 4e-07 Identities = 37/113 (32%), Positives = 54/113 (47%), Gaps = 17/113 (15%) Frame = +1 Query: 154 RSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYE-------------ARVSDHGL 294 R +AL A+G+ ++H P H ++ S N+LL + + ++SD GL Sbjct: 1392 RLKLALDIAKGMNYLHGWTPPILHRDLSSRNILLDHNIDPKNPVVSSRQDIKCKISDFGL 1451 Query: 295 PTLVGPSFSPTRVS----GYRAPEVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 L S S Y APEV S+K+DVYS+G++L ELLT P Sbjct: 1452 SRLKKEQASQMTQSVGCIPYMAPEVFKGDSNSEKSDVYSYGMVLFELLTSDEP 1504
>RMIL_AVEVR (P27966) Serine/threonine-protein kinase transforming protein Rmil| (EC 2.7.11.1) Length = 450 Score = 52.8 bits (125), Expect = 4e-07 Identities = 36/108 (33%), Positives = 61/108 (56%), Gaps = 9/108 (8%) Frame = +1 Query: 163 IALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGP---SFSPTRV 333 IA TA+G+ ++H+ + H ++KS+N+ L + ++ D GL T+ S ++ Sbjct: 182 IARQTAQGMDYLHAK--SIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQL 239 Query: 334 SG---YRAPEVT---DIRRVSQKADVYSFGVLLLELLTGKAPTHAVVN 459 SG + APEV D S ++DVY+FG++L EL+TG+ P + N Sbjct: 240 SGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINN 287
>BRAF1_CHICK (Q04982) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Rmil serine/threonine-protein kinase) (c-Rmil) Length = 806 Score = 52.8 bits (125), Expect = 4e-07 Identities = 36/108 (33%), Positives = 61/108 (56%), Gaps = 9/108 (8%) Frame = +1 Query: 163 IALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGP---SFSPTRV 333 IA TA+G+ ++H+ + H ++KS+N+ L + ++ D GL T+ S ++ Sbjct: 596 IARQTAQGMDYLHAK--SIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQL 653 Query: 334 SG---YRAPEVT---DIRRVSQKADVYSFGVLLLELLTGKAPTHAVVN 459 SG + APEV D S ++DVY+FG++L EL+TG+ P + N Sbjct: 654 SGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINN 701
>IRAK3_HUMAN (Q9Y616) Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1)| (IRAK-3) (IL-1 receptor-associated kinase M) (IRAK-M) Length = 596 Score = 52.8 bits (125), Expect = 4e-07 Identities = 29/110 (26%), Positives = 57/110 (51%), Gaps = 11/110 (10%) Frame = +1 Query: 136 PLDWEARSAIALATARGVAHIHSTGP-TASHGNIKSSNVLLTKSYEARVSDHGLPTL--- 303 PL W R I + ++ + ++H+ P + G+I S+N+LL ++ +++D + Sbjct: 261 PLPWHIRIGILIGISKAIHYLHNVQPCSVICGSISSANILLDDQFQPKLTDFAMAHFRSH 320 Query: 304 -------VGPSFSPTRVSGYRAPEVTDIRRVSQKADVYSFGVLLLELLTG 432 + + S ++ Y E ++S K DVYSFG++++E+LTG Sbjct: 321 LEHQSCTINMTSSSSKHLWYMPEEYIRQGKLSIKTDVYSFGIVIMEVLTG 370
>TAOK1_RAT (O88664) Serine/threonine-protein kinase TAO1 (EC 2.7.11.1)| (Thousand and one amino acid protein 1) Length = 1001 Score = 52.8 bits (125), Expect = 4e-07 Identities = 34/105 (32%), Positives = 55/105 (52%), Gaps = 3/105 (2%) Frame = +1 Query: 136 PLDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPS 315 PL +AI +G+A++HS T H +IK+ N+LLT+ + +++D G ++ P+ Sbjct: 122 PLQEVEIAAITHGALQGLAYLHSH--TMIHRDIKAGNILLTEPGQVKLADFGSASMASPA 179 Query: 316 FSPTRVSGYRAPEV---TDIRRVSQKADVYSFGVLLLELLTGKAP 441 S + APEV D + K DV+S G+ +EL K P Sbjct: 180 NSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPP 224
>TAOK1_MOUSE (Q5F2E8) Serine/threonine-protein kinase TAO1 (EC 2.7.11.1)| (Thousand and one amino acid protein 1) Length = 1001 Score = 52.8 bits (125), Expect = 4e-07 Identities = 34/105 (32%), Positives = 55/105 (52%), Gaps = 3/105 (2%) Frame = +1 Query: 136 PLDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPS 315 PL +AI +G+A++HS T H +IK+ N+LLT+ + +++D G ++ P+ Sbjct: 122 PLQEVEIAAITHGALQGLAYLHSH--TMIHRDIKAGNILLTEPGQVKLADFGSASMASPA 179 Query: 316 FSPTRVSGYRAPEV---TDIRRVSQKADVYSFGVLLLELLTGKAP 441 S + APEV D + K DV+S G+ +EL K P Sbjct: 180 NSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPP 224
>TAOK1_HUMAN (Q7L7X3) Serine/threonine-protein kinase TAO1 (EC 2.7.11.1)| (Thousand and one amino acid protein 1) (STE20-like kinase PSK2) (Kinase from chicken homolog B) (hKFC-B) Length = 1001 Score = 52.8 bits (125), Expect = 4e-07 Identities = 34/105 (32%), Positives = 55/105 (52%), Gaps = 3/105 (2%) Frame = +1 Query: 136 PLDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPS 315 PL +AI +G+A++HS T H +IK+ N+LLT+ + +++D G ++ P+ Sbjct: 122 PLQEVEIAAITHGALQGLAYLHSH--TMIHRDIKAGNILLTEPGQVKLADFGSASMASPA 179 Query: 316 FSPTRVSGYRAPEV---TDIRRVSQKADVYSFGVLLLELLTGKAP 441 S + APEV D + K DV+S G+ +EL K P Sbjct: 180 NSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPP 224
>RIPK3_MOUSE (Q9QZL0) Receptor-interacting serine/threonine-protein kinase 3 (EC| 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) (mRIP3) Length = 486 Score = 52.8 bits (125), Expect = 4e-07 Identities = 36/112 (32%), Positives = 55/112 (49%), Gaps = 12/112 (10%) Frame = +1 Query: 136 PLDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVG-- 309 P W + G+ ++HS P H ++K SN+LL A+++D GL T G Sbjct: 112 PRPWPLLCRLLQEVVLGMCYLHSLDPPLLHRDLKPSNILLDPELHAKLADFGLSTFQGGS 171 Query: 310 ----PSFSPTRVSG----YRAPEV--TDIRRVSQKADVYSFGVLLLELLTGK 435 S S +R SG Y PE+ + S+ +DVYSFG+L+ +L G+ Sbjct: 172 QSGSGSGSGSRDSGGTLAYLDPELLFKVNLKASKASDVYSFGILVWAVLAGR 223
>BRAF1_HUMAN (P15056) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (p94) (v-Raf murine sarcoma viral oncogene homolog B1) Length = 766 Score = 52.8 bits (125), Expect = 4e-07 Identities = 36/108 (33%), Positives = 61/108 (56%), Gaps = 9/108 (8%) Frame = +1 Query: 163 IALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGP---SFSPTRV 333 IA TA+G+ ++H+ + H ++KS+N+ L + ++ D GL T+ S ++ Sbjct: 556 IARQTAQGMDYLHAK--SIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQL 613 Query: 334 SG---YRAPEVT---DIRRVSQKADVYSFGVLLLELLTGKAPTHAVVN 459 SG + APEV D S ++DVY+FG++L EL+TG+ P + N Sbjct: 614 SGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINN 661
>BRAF1_COTJA (P34908) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (RMIL serine/threonine-protein kinase) (c-RMIL) Length = 807 Score = 52.8 bits (125), Expect = 4e-07 Identities = 36/108 (33%), Positives = 61/108 (56%), Gaps = 9/108 (8%) Frame = +1 Query: 163 IALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGP---SFSPTRV 333 IA TA+G+ ++H+ + H ++KS+N+ L + ++ D GL T+ S ++ Sbjct: 596 IARQTAQGMDYLHAK--SIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQL 653 Query: 334 SG---YRAPEVT---DIRRVSQKADVYSFGVLLLELLTGKAPTHAVVN 459 SG + APEV D S ++DVY+FG++L EL+TG+ P + N Sbjct: 654 SGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINN 701
>PKNK_MYCBO (Q7TXA9) Probable serine/threonine-protein kinase pknK (EC| 2.7.11.1) Length = 1110 Score = 52.8 bits (125), Expect = 4e-07 Identities = 34/105 (32%), Positives = 51/105 (48%), Gaps = 4/105 (3%) Frame = +1 Query: 136 PLDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPS 315 PLDW +I + A + H G H ++K N+LLT E +++D G+ + G Sbjct: 120 PLDWRETLSIGVKLAGALEAAHRVGTL--HRDVKPGNILLTDYGEPQLTDFGIARIAGGF 177 Query: 316 FSPTRV----SGYRAPEVTDIRRVSQKADVYSFGVLLLELLTGKA 438 + T V + APEV + + +DVYS G L +LTG A Sbjct: 178 ETATGVIAGSPAFTAPEVLEGASPTPASDVYSLGATLFCVLTGHA 222
>GCY3E_DROME (Q07553) Guanylate cyclase 32E precursor (EC 4.6.1.2)| Length = 1163 Score = 52.8 bits (125), Expect = 4e-07 Identities = 37/111 (33%), Positives = 56/111 (50%), Gaps = 10/111 (9%) Frame = +1 Query: 139 LDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPSF 318 LD S++ +G+ ++H + SHGN++SSN L+ + ++SD GL L Sbjct: 623 LDHMFISSLVSDILKGMIYLHDS-EIISHGNLRSSNCLIDSRWVCQISDFGLHELKAGQE 681 Query: 319 SPTRV------SGYRAPEVTDIR----RVSQKADVYSFGVLLLELLTGKAP 441 P + + APE+ R SQK DVYSFG+LL E++ K P Sbjct: 682 EPNKSELELKRALCMAPELLRDAYRPGRGSQKGDVYSFGILLYEMIGRKGP 732
>RMIL_AVII1 (P10533) Serine/threonine-protein kinase transforming protein Rmil| (EC 2.7.11.1) Length = 367 Score = 52.8 bits (125), Expect = 4e-07 Identities = 36/108 (33%), Positives = 61/108 (56%), Gaps = 9/108 (8%) Frame = +1 Query: 163 IALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGP---SFSPTRV 333 IA TA+G+ ++H+ + H ++KS+N+ L + ++ D GL T+ S ++ Sbjct: 166 IARQTAQGMDYLHAK--SIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQL 223 Query: 334 SG---YRAPEVT---DIRRVSQKADVYSFGVLLLELLTGKAPTHAVVN 459 SG + APEV D S ++DVY+FG++L EL+TG+ P + N Sbjct: 224 SGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINN 271
>BRAF1_MOUSE (P28028) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Fragment) Length = 328 Score = 52.8 bits (125), Expect = 4e-07 Identities = 36/108 (33%), Positives = 61/108 (56%), Gaps = 9/108 (8%) Frame = +1 Query: 163 IALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGP---SFSPTRV 333 IA TA+G+ ++H+ + H ++KS+N+ L + ++ D GL T+ S ++ Sbjct: 118 IARQTAQGMDYLHAK--SIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQL 175 Query: 334 SG---YRAPEVT---DIRRVSQKADVYSFGVLLLELLTGKAPTHAVVN 459 SG + APEV D S ++DVY+FG++L EL+TG+ P + N Sbjct: 176 SGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINN 223
>BYR2_SCHPO (P28829) Protein kinase byr2 (EC 2.7.11.25) (Protein kinase ste8)| (MAPK kinase kinase) (MAPKKK) Length = 659 Score = 52.4 bits (124), Expect = 6e-07 Identities = 30/99 (30%), Positives = 53/99 (53%), Gaps = 10/99 (10%) Frame = +1 Query: 175 TARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPSFSPTRVSGYR--- 345 T +G+ ++HS G H +IK +N+L+ + ++SD G+ + + + T+ G R Sbjct: 506 TLKGLEYLHSRGIV--HRDIKGANILVDNKGKIKISDFGISKKLELNSTSTKTGGARPSF 563 Query: 346 -------APEVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 APEV ++K D++S G L++E+LT K P Sbjct: 564 QGSSFWMAPEVVKQTMHTEKTDIWSLGCLVIEMLTSKHP 602
>ANPRB_BOVIN (P46197) Atrial natriuretic peptide receptor B precursor (ANP-B)| (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor) Length = 1047 Score = 52.4 bits (124), Expect = 6e-07 Identities = 35/110 (31%), Positives = 59/110 (53%), Gaps = 9/110 (8%) Frame = +1 Query: 139 LDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTL---VG 309 LDW R ++ +G+A +H++ ASHG++KSSN ++ + +++D+GL + Sbjct: 615 LDWMFRYSLINDLVKGMAFLHNS-IIASHGSLKSSNCVVDSRFVLKITDYGLASFRSTAE 673 Query: 310 PSFSPTRVSG--YRAPEVTDIRRV----SQKADVYSFGVLLLELLTGKAP 441 P S + + APE+ + QKADVYSFG++L E+ P Sbjct: 674 PDDSHALYAKKLWTAPELLSGNPLPTTGMQKADVYSFGIILQEIALRSGP 723
>TESK1_RAT (Q63572) Dual specificity testis-specific protein kinase 1 (EC| 2.7.12.1) (Testicular protein kinase 1) Length = 628 Score = 52.0 bits (123), Expect = 7e-07 Identities = 36/108 (33%), Positives = 55/108 (50%), Gaps = 11/108 (10%) Frame = +1 Query: 136 PLDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKS---YEARVSDHGLPTLV 306 PL W R +AL A+G+ ++H+ G H ++ S N L+ + + A V D GL + Sbjct: 141 PLSWPVRLHLALDIAQGLRYLHAKG--VFHRDLTSKNCLVRREDGGFTAVVGDFGLAEKI 198 Query: 307 -----GPSFSPTRVSG---YRAPEVTDIRRVSQKADVYSFGVLLLELL 426 G P V G + APEV +KADV++FG++L EL+ Sbjct: 199 PVYREGARKEPLAVVGSPYWMAPEVLRGELYDEKADVFAFGIVLCELI 246
>CDC15_YEAST (P27636) Cell division control protein 15 (EC 2.7.11.1)| Length = 974 Score = 52.0 bits (123), Expect = 7e-07 Identities = 34/117 (29%), Positives = 63/117 (53%), Gaps = 1/117 (0%) Frame = +1 Query: 100 RVLAGNRSSGLTPLDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARV 279 R L S+GL+ + E+++ + T G+ ++H G H +IK++N+LL+ ++ Sbjct: 108 RRLISRSSTGLS--ENESKTYVT-QTLLGLKYLHGEG--VIHRDIKAANILLSADNTVKL 162 Query: 280 SDHGLPTLVGPS-FSPTRVSGYRAPEVTDIRRVSQKADVYSFGVLLLELLTGKAPTH 447 +D G+ T+V S + + APE+ R S +D++S G ++E+LT P H Sbjct: 163 ADFGVSTIVNSSALTLAGTLNWMAPEILGNRGASTLSDIWSLGATVVEMLTKNPPYH 219
>RAF1_CHICK (P05625) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (RAF-1) (C-RAF) (MIL proto-oncogene serine/threonine-protein kinase) (C-MIL) Length = 647 Score = 52.0 bits (123), Expect = 7e-07 Identities = 35/108 (32%), Positives = 57/108 (52%), Gaps = 9/108 (8%) Frame = +1 Query: 163 IALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVG------PSFSP 324 IA TA+G+ ++H+ H ++KS+N+ L + ++ D GL T+ P Sbjct: 448 IARQTAQGMDYLHAKN--IIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQP 505 Query: 325 TRVSGYRAPEVT---DIRRVSQKADVYSFGVLLLELLTGKAPTHAVVN 459 T + APEV D S ++DVYS+G++L EL+TG+ P + N Sbjct: 506 TGSILWMAPEVIRMQDSNPFSFQSDVYSYGIVLYELMTGELPYSHINN 553
>PKNK_MYCTU (P95078) Probable serine/threonine-protein kinase pknK (EC| 2.7.11.1) Length = 1110 Score = 52.0 bits (123), Expect = 7e-07 Identities = 34/105 (32%), Positives = 50/105 (47%), Gaps = 4/105 (3%) Frame = +1 Query: 136 PLDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPS 315 PLDW +I + A + H G H ++K N+LLT E +++D G+ + G Sbjct: 120 PLDWRETLSIGVKLAGALEAAHRVGTL--HRDVKPGNILLTDYGEPQLTDFGIARIAGGF 177 Query: 316 FSPTRV----SGYRAPEVTDIRRVSQKADVYSFGVLLLELLTGKA 438 + T V + APEV + + +DVYS G L LTG A Sbjct: 178 ETATGVIAGSPAFTAPEVLEGASPTPASDVYSLGATLFCALTGHA 222
>TESK1_MOUSE (O70146) Dual specificity testis-specific protein kinase 1 (EC| 2.7.12.1) (Testicular protein kinase 1) Length = 627 Score = 52.0 bits (123), Expect = 7e-07 Identities = 36/108 (33%), Positives = 55/108 (50%), Gaps = 11/108 (10%) Frame = +1 Query: 136 PLDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKS---YEARVSDHGLPTLV 306 PL W R +AL A+G+ ++H+ G H ++ S N L+ + + A V D GL + Sbjct: 141 PLSWPVRLHLALDIAQGLRYLHAKG--VFHRDLTSKNCLVRREDRGFTAVVGDFGLAEKI 198 Query: 307 -----GPSFSPTRVSG---YRAPEVTDIRRVSQKADVYSFGVLLLELL 426 G P V G + APEV +KADV++FG++L EL+ Sbjct: 199 PVYREGTRKEPLAVVGSPYWMAPEVLRGELYDEKADVFAFGIVLCELI 246
>TAOK3_CHICK (Q9I9E0) Serine/threonine-protein kinase TAO3 (EC 2.7.11.1)| (Thousand and one amino acid protein 3) (Kinase from chicken) Length = 898 Score = 52.0 bits (123), Expect = 7e-07 Identities = 34/105 (32%), Positives = 55/105 (52%), Gaps = 3/105 (2%) Frame = +1 Query: 136 PLDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPS 315 PL +AI +G+A++HS H +IK+ N+LLT+ + +++D G ++V P+ Sbjct: 118 PLQEVEIAAITHGALQGLAYLHSH--CKIHRDIKAGNILLTEPGQVKLADFGSASIVSPA 175 Query: 316 FSPTRVSGYRAPEV---TDIRRVSQKADVYSFGVLLLELLTGKAP 441 S + APEV D + K DV+S G+ +EL K P Sbjct: 176 NSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPP 220
>RAF1_RAT (P11345) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Raf-1) (C-RAF) (cRaf) Length = 648 Score = 51.6 bits (122), Expect = 1e-06 Identities = 35/108 (32%), Positives = 57/108 (52%), Gaps = 9/108 (8%) Frame = +1 Query: 163 IALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVG------PSFSP 324 IA TA+G+ ++H+ H ++KS+N+ L + ++ D GL T+ P Sbjct: 448 IARQTAQGMDYLHAKN--IIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQP 505 Query: 325 TRVSGYRAPEVT---DIRRVSQKADVYSFGVLLLELLTGKAPTHAVVN 459 T + APEV D S ++DVYS+G++L EL+TG+ P + N Sbjct: 506 TGSVLWMAPEVIRMQDNNPFSFQSDVYSYGIVLYELMTGELPYSHINN 553
>RAF1_HUMAN (P04049) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Raf-1) (C-RAF) (cRaf) Length = 648 Score = 51.6 bits (122), Expect = 1e-06 Identities = 35/108 (32%), Positives = 57/108 (52%), Gaps = 9/108 (8%) Frame = +1 Query: 163 IALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVG------PSFSP 324 IA TA+G+ ++H+ H ++KS+N+ L + ++ D GL T+ P Sbjct: 448 IARQTAQGMDYLHAKN--IIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQP 505 Query: 325 TRVSGYRAPEVT---DIRRVSQKADVYSFGVLLLELLTGKAPTHAVVN 459 T + APEV D S ++DVYS+G++L EL+TG+ P + N Sbjct: 506 TGSVLWMAPEVIRMQDNNPFSFQSDVYSYGIVLYELMTGELPYSHINN 553
>TAO1B_XENLA (Q7ZYJ0) Serine/threonine-protein kinase TAO1-B (EC 2.7.11.1)| (Thousand and one amino acid protein 1-B) Length = 1001 Score = 51.6 bits (122), Expect = 1e-06 Identities = 34/105 (32%), Positives = 55/105 (52%), Gaps = 3/105 (2%) Frame = +1 Query: 136 PLDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPS 315 PL +AI +G+A++HS H +IK+ N+LLT+ + +++D G ++V P+ Sbjct: 122 PLQEIEIAAITHGALQGLAYLHSHN--LIHRDIKAGNILLTEPGQVKLADFGSASIVSPA 179 Query: 316 FSPTRVSGYRAPEV---TDIRRVSQKADVYSFGVLLLELLTGKAP 441 S + APEV D + K DV+S G+ +EL K P Sbjct: 180 NSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCVELAERKPP 224
>TNI3K_HUMAN (Q59H18) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 936 Score = 51.6 bits (122), Expect = 1e-06 Identities = 35/107 (32%), Positives = 59/107 (55%), Gaps = 6/107 (5%) Frame = +1 Query: 139 LDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVG--P 312 LD +++ IA+ A+G+ ++H+ H ++ S N+LL + A V+D G + Sbjct: 659 LDLQSKLIIAVDVAKGMEYLHNLTQPIIHRDLNSHNILLYEDGHAVVADFGESRFLQSLD 718 Query: 313 SFSPTRVSG---YRAPEV-TDIRRVSQKADVYSFGVLLLELLTGKAP 441 + T+ G + APEV T R + KADV+S+ + L E+LTG+ P Sbjct: 719 EDNMTKQPGNLRWMAPEVFTQCTRYTIKADVFSYALCLWEILTGEIP 765
>M3K9_HUMAN (P80192) Mitogen-activated protein kinase kinase kinase 9 (EC| 2.7.11.25) (Mixed lineage kinase 1) Length = 1104 Score = 51.2 bits (121), Expect = 1e-06 Identities = 40/129 (31%), Positives = 63/129 (48%), Gaps = 11/129 (8%) Frame = +1 Query: 100 RVLAGNRSSGLTPLDWEARSAIALATARGVAHIHSTGPTAS-HGNIKSSNVLLTKSYE-- 270 RVL+G R ++W A+ ARG+ ++H H ++KSSN+L+ + E Sbjct: 230 RVLSGKRIPPDILVNW------AVQIARGMNYLHDEAIVPIIHRDLKSSNILILQKVENG 283 Query: 271 ------ARVSDHGLPTLVGPSFSPTRVSGYR--APEVTDIRRVSQKADVYSFGVLLLELL 426 +++D GL + + Y APEV S+ +DV+S+GVLL ELL Sbjct: 284 DLSNKILKITDFGLAREWHRTTKMSAAGTYAWMAPEVIRASMFSKGSDVWSYGVLLWELL 343 Query: 427 TGKAPTHAV 453 TG+ P + Sbjct: 344 TGEVPFRGI 352
>SHK1_SCHPO (P50527) Serine/threonine-protein kinase pak1/shk1 (EC 2.7.11.1)| Length = 658 Score = 51.2 bits (121), Expect = 1e-06 Identities = 30/99 (30%), Positives = 53/99 (53%), Gaps = 4/99 (4%) Frame = +1 Query: 157 SAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPSFSP-TRV 333 +AI T G+ H+H G H +IKS N+LL+ + +++D G + + + T + Sbjct: 483 AAICKETLEGLQHLHENGIV--HRDIKSDNILLSLQGDIKLTDFGFCAQIDSNMTKRTTM 540 Query: 334 SG---YRAPEVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 G + APEV + K DV+S G++ +E++ G+ P Sbjct: 541 VGTPYWMAPEVVTRKEYGFKVDVWSLGIMAIEMVEGEPP 579
>TNI3K_MOUSE (Q5GIG6) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 833 Score = 51.2 bits (121), Expect = 1e-06 Identities = 36/107 (33%), Positives = 58/107 (54%), Gaps = 6/107 (5%) Frame = +1 Query: 139 LDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVG--P 312 LD +++ IA+ A+G+ ++HS H ++ S N+LL + A V+D G + Sbjct: 556 LDLQSKLIIAVDVAKGMEYLHSLTQPIIHRDLNSHNILLYEDGHAVVADFGESRFLQSLD 615 Query: 313 SFSPTRVSG---YRAPEV-TDIRRVSQKADVYSFGVLLLELLTGKAP 441 + T+ G + APEV T R + KADV+S+ + L ELL G+ P Sbjct: 616 EDNMTKQPGNLRWMAPEVFTQCTRYTIKADVFSYALCLWELLIGEIP 662
>ANPRB_HUMAN (P20594) Atrial natriuretic peptide receptor B precursor (ANP-B)| (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor) Length = 1047 Score = 51.2 bits (121), Expect = 1e-06 Identities = 33/110 (30%), Positives = 58/110 (52%), Gaps = 9/110 (8%) Frame = +1 Query: 139 LDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPSF 318 LDW R ++ +G+A +H++ +SHG++KSSN ++ + +++D+GL + + Sbjct: 615 LDWMFRYSLINDLVKGMAFLHNS-IISSHGSLKSSNCVVDSRFVLKITDYGLASFRSTAE 673 Query: 319 SPTRVSGYR-----APEVTDIRRVS----QKADVYSFGVLLLELLTGKAP 441 + Y APE+ + QKADVYSFG++L E+ P Sbjct: 674 PDDSHALYAKKLWTAPELLSGNPLPTTGMQKADVYSFGIILQEIALRSGP 723
>RAF1_XENLA (P09560) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (C-RAF) Length = 638 Score = 50.8 bits (120), Expect = 2e-06 Identities = 36/108 (33%), Positives = 57/108 (52%), Gaps = 15/108 (13%) Frame = +1 Query: 163 IALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPSFSPTRVSG- 339 IA TA+G+ ++H+ H ++KS+N+ L + ++ D GL T+ TR SG Sbjct: 439 IARQTAQGMDYLHAKN--IIHRDMKSNNIFLHEGLTVKIGDFGLATV------KTRWSGS 490 Query: 340 -----------YRAPEVT---DIRRVSQKADVYSFGVLLLELLTGKAP 441 + APEV D S ++DVYS+G++L EL+TG+ P Sbjct: 491 QQVEQLTGSILWMAPEVIRMQDNNPFSFQSDVYSYGIVLYELMTGELP 538
>MIL_AVIMH (P00531) Serine/threonine-protein kinase transforming protein mil| (EC 2.7.11.1) Length = 380 Score = 50.8 bits (120), Expect = 2e-06 Identities = 35/108 (32%), Positives = 56/108 (51%), Gaps = 9/108 (8%) Frame = +1 Query: 163 IALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVG------PSFSP 324 IA TA+G+ ++H+ H ++KS+N+ L ++ D GL T+ P Sbjct: 181 IARQTAQGMDYLHAKN--IIHRDMKSNNIFLHGGLTVKIGDFGLATVKSRWSGSQQVEQP 238 Query: 325 TRVSGYRAPEVT---DIRRVSQKADVYSFGVLLLELLTGKAPTHAVVN 459 T + APEV D S ++DVYS+G++L EL+TG+ P + N Sbjct: 239 TGSILWMAPEVIRMQDSNPFSFQSDVYSYGIVLYELMTGELPYSHINN 286
>GPRK2_DROME (P32866) G protein-coupled receptor kinase 2 (EC 2.7.11.16)| Length = 714 Score = 50.4 bits (119), Expect = 2e-06 Identities = 34/96 (35%), Positives = 47/96 (48%), Gaps = 4/96 (4%) Frame = +1 Query: 166 ALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPSFSPTR----V 333 A A G+ H+H G + + K N+LL R+SD GL + P R Sbjct: 416 AAEVACGLQHLHKQGIV--YRDCKPENILLDDHGHVRISDLGLAVEI-PEGEMVRGRVGT 472 Query: 334 SGYRAPEVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 GY APEV D + + D +SFG LL E++ G+AP Sbjct: 473 VGYMAPEVIDNEKYAFSPDWFSFGCLLYEMIEGQAP 508
>MP2K4_HUMAN (P45985) Dual specificity mitogen-activated protein kinase kinase 4| (EC 2.7.12.2) (MAP kinase kinase 4) (JNK-activating kinase 1) (c-Jun N-terminal kinase kinase 1) (JNKK) (SAPK/ERK kinase 1) (SEK1) Length = 399 Score = 50.4 bits (119), Expect = 2e-06 Identities = 36/105 (34%), Positives = 53/105 (50%), Gaps = 7/105 (6%) Frame = +1 Query: 148 EARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPSFSPT 327 E I LAT + + H+ H +IK SN+LL +S ++ D G+ + S + T Sbjct: 203 EILGKITLATVKALNHLKENLKII-HRDIKPSNILLDRSGNIKLCDFGISGQLVDSIAKT 261 Query: 328 RVSG---YRAPEVTDIRRVSQ----KADVYSFGVLLLELLTGKAP 441 R +G Y APE D Q ++DV+S G+ L EL TG+ P Sbjct: 262 RDAGCRPYMAPERIDPSASRQGYDVRSDVWSLGITLYELATGRFP 306
>MP2K4_MOUSE (P47809) Dual specificity mitogen-activated protein kinase kinase 4| (EC 2.7.12.2) (MAP kinase kinase 4) (MAPKK 4) (MAPK/ERK kinase 4) (JNK-activating kinase 1) (C-JUN N-terminal kinase kinase 1) (JNK kinase 1) (JNKK 1) (SAPK/ERK kinase 1) (SE Length = 397 Score = 50.4 bits (119), Expect = 2e-06 Identities = 36/105 (34%), Positives = 53/105 (50%), Gaps = 7/105 (6%) Frame = +1 Query: 148 EARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPSFSPT 327 E I LAT + + H+ H +IK SN+LL +S ++ D G+ + S + T Sbjct: 201 EILGKITLATVKALNHLKENLKII-HRDIKPSNILLDRSGNIKLCDFGISGQLVDSIAKT 259 Query: 328 RVSG---YRAPEVTDIRRVSQ----KADVYSFGVLLLELLTGKAP 441 R +G Y APE D Q ++DV+S G+ L EL TG+ P Sbjct: 260 RDAGCRPYMAPERIDPSASRQGYDVRSDVWSLGITLYELATGRFP 304
>STE20_YEAST (Q03497) Serine/threonine-protein kinase STE20 (EC 2.7.11.1)| Length = 939 Score = 50.4 bits (119), Expect = 2e-06 Identities = 28/98 (28%), Positives = 52/98 (53%), Gaps = 4/98 (4%) Frame = +1 Query: 160 AIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGP-SFSPTRVS 336 A+ T G+ +HS G H +IKS N+LL+ + +++D G + + T + Sbjct: 718 AVCRETLSGLEFLHSKG--VLHRDIKSDNILLSMEGDIKLTDFGFCAQINELNLKRTTMV 775 Query: 337 G---YRAPEVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 G + APEV + K D++S G++++E++ G+ P Sbjct: 776 GTPYWMAPEVVSRKEYGPKVDIWSLGIMIIEMIEGEPP 813
>TAO1A_XENLA (Q6NU21) Serine/threonine-protein kinase TAO1-A (EC 2.7.11.1)| (Thousand and one amino acid protein 1-A) Length = 1001 Score = 50.4 bits (119), Expect = 2e-06 Identities = 33/105 (31%), Positives = 54/105 (51%), Gaps = 3/105 (2%) Frame = +1 Query: 136 PLDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPS 315 PL +AI +G+A++HS H +IK+ N+LLT+ + +++D G ++ P+ Sbjct: 122 PLQEIEIAAITHGALQGLAYLHSHN--LIHRDIKAGNILLTEPGQVKLADFGSASIASPA 179 Query: 316 FSPTRVSGYRAPEV---TDIRRVSQKADVYSFGVLLLELLTGKAP 441 S + APEV D + K DV+S G+ +EL K P Sbjct: 180 NSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPP 224
>SHK2_SCHPO (Q10056) Serine/threonine-protein kinase shk2 (EC 2.7.11.1)| Length = 589 Score = 50.4 bits (119), Expect = 2e-06 Identities = 28/97 (28%), Positives = 47/97 (48%), Gaps = 4/97 (4%) Frame = +1 Query: 163 IALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHG----LPTLVGPSFSPTR 330 I L T +G+ H+H+ H +IKS NVLL S +++D G L + Sbjct: 414 ICLETCKGIQHLHARN--IIHRDIKSDNVLLDNSGNIKITDFGFCARLSNRTNKRVTMVG 471 Query: 331 VSGYRAPEVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 + APEV K D++S G++++E++ + P Sbjct: 472 TPYWMAPEVVKQNEYGTKVDIWSLGIMIIEMIENEPP 508
>WNK4_RAT (Q7TPK6) Serine/threonine-protein kinase WNK4 (EC 2.7.11.1)| (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4) Length = 1222 Score = 50.4 bits (119), Expect = 2e-06 Identities = 30/90 (33%), Positives = 50/90 (55%), Gaps = 3/90 (3%) Frame = +1 Query: 181 RGVAHIHSTGPTASHGNIKSSNVLLT-KSYEARVSDHGLPTLVGPSFSPTRVSG--YRAP 351 RG+ +HS P H ++K NV +T S ++ D GL TL SF+ + + + AP Sbjct: 283 RGLHFLHSRVPPILHRDLKCDNVFITGPSGSVKIGDLGLATLKRASFAKSVIGTPEFMAP 342 Query: 352 EVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 E+ + + + DVY+FG+ +LE+ T + P Sbjct: 343 EMYE-EKYDEAVDVYAFGMCMLEMATSEYP 371
>WNK4_MOUSE (Q80UE6) Serine/threonine-protein kinase WNK4 (EC 2.7.11.1)| (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4) Length = 1222 Score = 50.4 bits (119), Expect = 2e-06 Identities = 30/90 (33%), Positives = 50/90 (55%), Gaps = 3/90 (3%) Frame = +1 Query: 181 RGVAHIHSTGPTASHGNIKSSNVLLT-KSYEARVSDHGLPTLVGPSFSPTRVSG--YRAP 351 RG+ +HS P H ++K NV +T S ++ D GL TL SF+ + + + AP Sbjct: 283 RGLHFLHSRVPPILHRDLKCDNVFITGPSGSVKIGDLGLATLKRASFAKSVIGTPEFMAP 342 Query: 352 EVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 E+ + + + DVY+FG+ +LE+ T + P Sbjct: 343 EMYE-EKYDEAVDVYAFGMCMLEMATSEYP 371
>SRMS_HUMAN (Q9H3Y6) Tyrosine-protein kinase Srms (EC 2.7.10.2)| Length = 488 Score = 50.4 bits (119), Expect = 2e-06 Identities = 35/104 (33%), Positives = 53/104 (50%), Gaps = 6/104 (5%) Frame = +1 Query: 166 ALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLV-----GPSFSPTR 330 A A G++++ H ++ + NVL+ +V+D GL L+ PS S Sbjct: 331 ACQVAEGMSYLEEQ--RVVHRDLAARNVLVDDGLACKVADFGLARLLKDDIYSPSSSSKI 388 Query: 331 VSGYRAPEVTDIRRVSQKADVYSFGVLLLELLT-GKAPTHAVVN 459 + APE + R SQK+DV+SFGVLL E+ T G+ P + N Sbjct: 389 PVKWTAPEAANYRVFSQKSDVWSFGVLLHEVFTYGQCPYEGMTN 432
>KS6A2_HUMAN (Q15349) Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1)| (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (MAP kinase-activated protein kinase 1c) (MAPKAPK1C) Length = 733 Score = 50.4 bits (119), Expect = 2e-06 Identities = 32/92 (34%), Positives = 49/92 (53%), Gaps = 4/92 (4%) Frame = +1 Query: 178 ARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLV----GPSFSPTRVSGYR 345 A + H+HS G + ++K N+LL + +++D GL ++S Y Sbjct: 169 ALALDHLHSLG--IIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKRAYSFCGTIEYM 226 Query: 346 APEVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 APEV + R +Q AD +SFGVL+ E+LTG P Sbjct: 227 APEVVNRRGHTQSADWWSFGVLMFEMLTGSLP 258 Score = 35.8 bits (81), Expect = 0.055 Identities = 27/103 (26%), Positives = 45/103 (43%), Gaps = 8/103 (7%) Frame = +1 Query: 157 SAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEA----RVSDHGLPTLV----GP 312 S + + + ++HS G H ++K SN+L + RV D G + G Sbjct: 510 SDVLCTITKTMDYLHSQGVV--HRDLKPSNILYRDESGSPESIRVCDFGFAKQLRAGNGL 567 Query: 313 SFSPTRVSGYRAPEVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 +P + + APEV + D++S G+LL +L G P Sbjct: 568 LMTPCYTANFVAPEVLKRQGYDAACDIWSLGILLYTMLAGFTP 610
>MOS_MSVMT (P32593) Serine/threonine-protein kinase transforming protein mos| (EC 2.7.11.1) Length = 354 Score = 50.1 bits (118), Expect = 3e-06 Identities = 30/99 (30%), Positives = 53/99 (53%), Gaps = 7/99 (7%) Frame = +1 Query: 166 ALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHG----LPTLVGPSFSPTRV 333 +L G+ +HS + H ++K +N+L+++ ++SD G L L G SP + Sbjct: 190 SLDVVNGLLFLHSQ--SILHLDLKPANILISEQDVCKISDFGCSQKLQVLRGRQASPPHI 247 Query: 334 SG---YRAPEVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 G ++APE+ + KAD+YSFG+ L ++ T + P Sbjct: 248 GGTYTHQAPEILKGEIATPKADIYSFGITLWQMTTREVP 286
>STE7_YEAST (P06784) Serine/threonine-protein kinase STE7 (EC 2.7.12.2)| Length = 515 Score = 50.1 bits (118), Expect = 3e-06 Identities = 40/128 (31%), Positives = 63/128 (49%), Gaps = 2/128 (1%) Frame = +1 Query: 64 GNCD*L*CSCRRRVLAGNRSSGLTPLDWEARSAIALATARGVAHIHSTGPTASHGNIKSS 243 G+ D + +R V G SS T + S IA G+ H++ H +IK S Sbjct: 277 GSLDKILSVYKRFVQRGTVSSKKTWFNELTISKIAYGVLNGLDHLYRQYKII-HRDIKPS 335 Query: 244 NVLLTKSYEARVSDHGLPTLVGPSFSPTRV--SGYRAPEVTDIRRVSQKADVYSFGVLLL 417 NVL+ + ++ D G+ + S + T V S Y +PE S K DV+S G++++ Sbjct: 336 NVLINSKGQIKLCDFGVSKKLINSIADTFVGTSTYMSPERIQGNVYSIKGDVWSLGLMII 395 Query: 418 ELLTGKAP 441 EL+TG+ P Sbjct: 396 ELVTGEFP 403
>MK08_XENLA (Q8QHK8) Mitogen-activated protein kinase 8 (EC 2.7.11.24)| (Stress-activated protein kinase JNK1) Length = 426 Score = 50.1 bits (118), Expect = 3e-06 Identities = 32/101 (31%), Positives = 48/101 (47%), Gaps = 3/101 (2%) Frame = +1 Query: 139 LDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPSF 318 LD E S + G+ H+HS G H ++K SN+++ ++ D GL G SF Sbjct: 123 LDHERMSYLLYQMLCGIKHLHSAG--IIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF 180 Query: 319 SPTR---VSGYRAPEVTDIRRVSQKADVYSFGVLLLELLTG 432 T YRAPEV + D++S G +L E++ G Sbjct: 181 MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCILGEMIKG 221
>ANPRB_ANGJA (P55202) Atrial natriuretic peptide receptor B precursor (ANP-B)| (ANPRB) (GC-B) (Guanylate cyclase) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor) Length = 1050 Score = 50.1 bits (118), Expect = 3e-06 Identities = 33/110 (30%), Positives = 56/110 (50%), Gaps = 9/110 (8%) Frame = +1 Query: 139 LDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPSF 318 LDW R ++ +G+ +H++ SHGN+KSSN ++ + +++D+GL + Sbjct: 619 LDWMFRYSLINDIVKGMNFLHNSY-IGSHGNLKSSNCVVDSRFVLKITDYGLASFRSSCE 677 Query: 319 SPTRVSGY-----RAPEVTDIRR----VSQKADVYSFGVLLLELLTGKAP 441 + + Y APE+ R +QK DVYSFG++L E+ P Sbjct: 678 NEDSHALYAKKLWTAPELLIYDRHPPQGTQKGDVYSFGIILQEIALRNGP 727
>SKM1_YEAST (Q12469) Serine/threonine-protein kinase SKM1 (EC 2.7.11.1)| (Protein kinase 75490 D) Length = 655 Score = 50.1 bits (118), Expect = 3e-06 Identities = 32/124 (25%), Positives = 58/124 (46%), Gaps = 11/124 (8%) Frame = +1 Query: 103 VLAGNRSSGLTPLDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVS 282 V N +PL+ + I T +G+ +H+ H +IKS N+LL +++ Sbjct: 467 VARSNTGEHSSPLNENQMAYIVKETCQGLKFLHNK--KIIHRDIKSDNILLNSQGLVKIT 524 Query: 283 DHGL-----------PTLVGPSFSPTRVSGYRAPEVTDIRRVSQKADVYSFGVLLLELLT 429 D G T+VG + + APE+ + + +K DV+S G++L+E++ Sbjct: 525 DFGFCVELTEKRSKRATMVGTPY-------WMAPEIVNQKGYDEKVDVWSLGIMLIEMIE 577 Query: 430 GKAP 441 G+ P Sbjct: 578 GEPP 581
>PKN1_THETN (Q8R9T6) Probable serine/threonine-protein kinase Sps1 (EC| 2.7.11.1) Length = 625 Score = 50.1 bits (118), Expect = 3e-06 Identities = 33/107 (30%), Positives = 52/107 (48%), Gaps = 5/107 (4%) Frame = +1 Query: 136 PLDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLV-GP 312 PL+ + IA R + H H H +IK N+L+T +V+D G+ G Sbjct: 105 PLEVKRAVEIASQVCRALDHAHKN--KIIHRDIKPQNILVTDEDVVKVTDFGIARAANGA 162 Query: 313 SFSPTR----VSGYRAPEVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 + + T + Y +PE V ++ D+YS G++L E+LTGK P Sbjct: 163 TITYTGDVIGTAYYFSPEQAKGSIVDERTDIYSLGIVLFEMLTGKVP 209
>TAOK3_HUMAN (Q9H2K8) Serine/threonine-protein kinase TAO3 (EC 2.7.11.1)| (Thousand and one amino acid protein 3) (Jun kinase-inhibitory kinase) (JNK/SAPK-inhibitory kinase) (Dendritic cell-derived protein kinase) (Cutaneous T-cell lymphoma tumor antigen H Length = 898 Score = 50.1 bits (118), Expect = 3e-06 Identities = 32/105 (30%), Positives = 53/105 (50%), Gaps = 3/105 (2%) Frame = +1 Query: 136 PLDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPS 315 PL +AI G+A++HS H +IK+ N+LLT+ + +++D G ++ P+ Sbjct: 118 PLQEVEIAAITHGALHGLAYLHSHA--LIHRDIKAGNILLTEPGQVKLADFGSASMASPA 175 Query: 316 FSPTRVSGYRAPEV---TDIRRVSQKADVYSFGVLLLELLTGKAP 441 S + APEV D + K D++S G+ +EL K P Sbjct: 176 NSFVGTPYWMAPEVILAMDEGQYDGKVDIWSLGITCIELAERKPP 220
>MOS_MSVMO (P00538) Serine/threonine-protein kinase transforming protein mos| (EC 2.7.11.1) Length = 374 Score = 49.7 bits (117), Expect = 4e-06 Identities = 30/99 (30%), Positives = 53/99 (53%), Gaps = 7/99 (7%) Frame = +1 Query: 166 ALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHG----LPTLVGPSFSPTRV 333 +L G+ +HS + H ++K +N+L+++ ++SD G L L G SP + Sbjct: 210 SLDVVNGLLFLHSQ--SILHLDLKPANILISEQDVCKISDFGCSQKLQDLRGRQASPPHI 267 Query: 334 SG---YRAPEVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 G ++APE+ + KAD+YSFG+ L ++ T + P Sbjct: 268 GGTYTHQAPEILKGEIATPKADIYSFGITLWQMTTREVP 306
>PKN6_MYXXA (P54738) Serine/threonine-protein kinase pkn6 (EC 2.7.11.1)| Length = 710 Score = 49.7 bits (117), Expect = 4e-06 Identities = 33/111 (29%), Positives = 52/111 (46%), Gaps = 12/111 (10%) Frame = +1 Query: 163 IALATARGVAHIHS-----TGPTAS--HGNIKSSNVLLTKSYEARVSDHGLPTLVGPSFS 321 + A A G+A+ H TG H ++ N+L+++ +V D G+ + G Sbjct: 114 VVAAAAEGLAYAHEFRDVETGEPLGLIHRDVSPDNILVSRQGAVKVVDFGIAKVAGQGHR 173 Query: 322 PTR--VSG---YRAPEVTDIRRVSQKADVYSFGVLLLELLTGKAPTHAVVN 459 V G Y PE + + ++ DVY+ GV+L ELLTGK P A + Sbjct: 174 TLTGVVKGKVAYMPPEQLQAKAMDRRVDVYALGVVLYELLTGKRPFDATTD 224
>SRMS_MOUSE (Q62270) Tyrosine-protein kinase Srms (EC 2.7.10.2) (PTK70)| Length = 496 Score = 49.3 bits (116), Expect = 5e-06 Identities = 34/104 (32%), Positives = 55/104 (52%), Gaps = 6/104 (5%) Frame = +1 Query: 166 ALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPS-FSPTRVSG- 339 A A G++++ H ++ + NVL+ +V+D GL L+ +SP+ S Sbjct: 335 ACQVAEGMSYLEER--RVVHRDLAARNVLVGDDLTCKVADFGLARLLKDDVYSPSSGSKI 392 Query: 340 ---YRAPEVTDIRRVSQKADVYSFGVLLLELLT-GKAPTHAVVN 459 + APE + R SQK+DV+SFG+LL E+ T G+ P + N Sbjct: 393 PVKWTAPEAANYRVFSQKSDVWSFGILLYEVFTYGQCPYEGMTN 436
>RAF1_MOUSE (Q99N57) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Raf-1) (C-RAF) (cRaf) Length = 648 Score = 49.3 bits (116), Expect = 5e-06 Identities = 33/102 (32%), Positives = 54/102 (52%), Gaps = 9/102 (8%) Frame = +1 Query: 163 IALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVG------PSFSP 324 IA TA+G+ ++H+ H ++KS+N+ L + ++ D GL T+ P Sbjct: 448 IARQTAQGMDYLHAKN--IIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQP 505 Query: 325 TRVSGYRAPEVT---DIRRVSQKADVYSFGVLLLELLTGKAP 441 T + APEV D S ++DVYS+G++L EL+ G+ P Sbjct: 506 TGSVLWMAPEVIRMQDDNPFSFQSDVYSYGIVLYELMAGELP 547
>RAF_MSV36 (P00532) Serine/threonine-protein kinase transforming protein raf| (EC 2.7.11.1) Length = 323 Score = 49.3 bits (116), Expect = 5e-06 Identities = 33/102 (32%), Positives = 54/102 (52%), Gaps = 9/102 (8%) Frame = +1 Query: 163 IALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVG------PSFSP 324 IA TA+G+ ++H+ H ++KS+N+ L + ++ D GL T+ P Sbjct: 123 IARQTAQGMDYLHAKN--IIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQP 180 Query: 325 TRVSGYRAPEVT---DIRRVSQKADVYSFGVLLLELLTGKAP 441 T + APEV D S ++DVYS+G++L EL+ G+ P Sbjct: 181 TGSVLWMAPEVIRMQDDNPFSFQSDVYSYGIVLYELMAGELP 222
>WNK4_HUMAN (Q96J92) Serine/threonine-protein kinase WNK4 (EC 2.7.11.1)| (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4) Length = 1243 Score = 49.3 bits (116), Expect = 5e-06 Identities = 29/90 (32%), Positives = 50/90 (55%), Gaps = 3/90 (3%) Frame = +1 Query: 181 RGVAHIHSTGPTASHGNIKSSNVLLT-KSYEARVSDHGLPTLVGPSFSPTRVSG--YRAP 351 RG+ +HS P H ++K NV +T + ++ D GL TL SF+ + + + AP Sbjct: 286 RGLHFLHSRVPPILHRDLKCDNVFITGPTGSVKIGDLGLATLKRASFAKSVIGTPEFMAP 345 Query: 352 EVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 E+ + + + DVY+FG+ +LE+ T + P Sbjct: 346 EMYE-EKYDEAVDVYAFGMCMLEMATSEYP 374
>MK14B_DROME (O61443) Mitogen-activated protein kinase 14B (EC 2.7.11.24) (MAP| kinase p38b) (D-p38b) Length = 365 Score = 49.3 bits (116), Expect = 5e-06 Identities = 30/87 (34%), Positives = 47/87 (54%), Gaps = 2/87 (2%) Frame = +1 Query: 181 RGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPSFSP-TRVSGYRAPEV 357 RG+ +IHS G H ++K SN+ + + E R+ D GL + YRAPE+ Sbjct: 139 RGLKYIHSAG--VIHRDLKPSNIAVNEDCELRILDFGLARPAESEMTGYVATRWYRAPEI 196 Query: 358 T-DIRRVSQKADVYSFGVLLLELLTGK 435 + +Q AD++S G ++ ELLTG+ Sbjct: 197 MLNWMHYNQTADIWSVGCIMAELLTGR 223
>STK39_RAT (O88506) STE20/SPS1-related proline-alanine-rich protein kinase (EC| 2.7.11.1) (Ste-20-related kinase) (Serine/threonine-protein kinase 39) (Pancreatic serine/threonine-protein kinase) (PS/TK) (PSTK1) Length = 553 Score = 49.3 bits (116), Expect = 5e-06 Identities = 30/98 (30%), Positives = 50/98 (51%), Gaps = 10/98 (10%) Frame = +1 Query: 184 GVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPSFSPTR---------VS 336 G+ ++H G H ++K+ N+LL + +++D G+ + TR Sbjct: 188 GLDYLHRNGQI--HRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTRNKVRKTFVGTP 245 Query: 337 GYRAPEVTD-IRRVSQKADVYSFGVLLLELLTGKAPTH 447 + APEV + +R KAD++SFG+ +EL TG AP H Sbjct: 246 CWMAPEVMEQVRGYDFKADMWSFGITAIELATGAAPYH 283
>STK39_MOUSE (Q9Z1W9) STE20/SPS1-related proline-alanine-rich protein kinase (EC| 2.7.11.1) (Ste-20-related kinase) (Serine/threonine-protein kinase 39) Length = 556 Score = 49.3 bits (116), Expect = 5e-06 Identities = 30/98 (30%), Positives = 50/98 (51%), Gaps = 10/98 (10%) Frame = +1 Query: 184 GVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPSFSPTR---------VS 336 G+ ++H G H ++K+ N+LL + +++D G+ + TR Sbjct: 191 GLDYLHRNGQI--HRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTRNKVRKTFVGTP 248 Query: 337 GYRAPEVTD-IRRVSQKADVYSFGVLLLELLTGKAPTH 447 + APEV + +R KAD++SFG+ +EL TG AP H Sbjct: 249 CWMAPEVMEQVRGYDFKADMWSFGITAIELATGAAPYH 286
>AVR2A_XENLA (P27039) Activin receptor type 2A precursor (EC 2.7.11.30) (Activin| receptor type II) (ACTR-II) Length = 514 Score = 49.3 bits (116), Expect = 5e-06 Identities = 37/127 (29%), Positives = 56/127 (44%), Gaps = 19/127 (14%) Frame = +1 Query: 139 LDWEARSAIALATARGVAHIHST--------GPTASHGNIKSSNVLLTKSYEARVSDHGL 294 + W IA ARG++H+H P +H +IKS NVLL + A ++D GL Sbjct: 285 VSWNELCLIAETMARGLSHLHEDIPGLKDGHKPAVAHRDIKSKNVLLKNNLTACIADFGL 344 Query: 295 P------TLVGPSFSPTRVSGYRAPEVTD-----IRRVSQKADVYSFGVLLLELLTGKAP 441 G + Y APEV + R + D+Y+FG++L EL + Sbjct: 345 ALKFEAGKSAGDTHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAFGLVLWELASRCTA 404 Query: 442 THAVVNE 462 + V+E Sbjct: 405 SDGPVDE 411
>KS6A2_MOUSE (Q9WUT3) Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1)| (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (Protein-tyrosine kinase Mpk-9) (MAP kinase-activated protein kinase 1c) (M Length = 733 Score = 49.3 bits (116), Expect = 5e-06 Identities = 31/92 (33%), Positives = 48/92 (52%), Gaps = 4/92 (4%) Frame = +1 Query: 178 ARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGP----SFSPTRVSGYR 345 A + H+H G + ++K N+LL + +++D GL ++S Y Sbjct: 169 ALALDHLHGLG--IIYRDLKPENILLDEEGHIKITDFGLSKEATDHDKRAYSFCGTIEYM 226 Query: 346 APEVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 APEV + R +Q AD +SFGVL+ E+LTG P Sbjct: 227 APEVVNRRGHTQSADWWSFGVLMFEMLTGSLP 258 Score = 38.5 bits (88), Expect = 0.008 Identities = 29/103 (28%), Positives = 45/103 (43%), Gaps = 8/103 (7%) Frame = +1 Query: 157 SAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSY----EARVSDHGLPTLV----GP 312 S + AR + ++HS G H ++K SN+L R+ D G + G Sbjct: 510 SDVLYTIARTMDYLHSQGVV--HRDLKPSNILYMDESGNPESIRICDFGFAKQLRAENGL 567 Query: 313 SFSPTRVSGYRAPEVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 +P + + APEV + DV+S G+LL +L G P Sbjct: 568 LMTPCYTANFVAPEVLKRQGYDAACDVWSLGILLYTMLAGFTP 610
>STK39_HUMAN (Q9UEW8) STE20/SPS1-related proline-alanine-rich protein kinase (EC| 2.7.11.1) (Ste-20-related kinase) (Serine/threonine-protein kinase 39) (DCHT) Length = 547 Score = 49.3 bits (116), Expect = 5e-06 Identities = 30/98 (30%), Positives = 50/98 (51%), Gaps = 10/98 (10%) Frame = +1 Query: 184 GVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPSFSPTR---------VS 336 G+ ++H G H ++K+ N+LL + +++D G+ + TR Sbjct: 181 GLDYLHRNGQI--HRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTRNKVRKTFVGTP 238 Query: 337 GYRAPEVTD-IRRVSQKADVYSFGVLLLELLTGKAPTH 447 + APEV + +R KAD++SFG+ +EL TG AP H Sbjct: 239 CWMAPEVMEQVRGYDFKADMWSFGITAIELATGAAPYH 276
>KS6A3_MOUSE (P18654) Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1)| (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (MAP kinase-activated protein kinase 1b) (MAPKAPK1B) Length = 740 Score = 48.9 bits (115), Expect = 6e-06 Identities = 32/92 (34%), Positives = 49/92 (53%), Gaps = 4/92 (4%) Frame = +1 Query: 178 ARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLV----GPSFSPTRVSGYR 345 A + H+HS G + ++K N+LL + +++D GL ++S Y Sbjct: 178 ALALDHLHSLG--IIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYM 235 Query: 346 APEVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 APEV + R +Q AD +SFGVL+ E+LTG P Sbjct: 236 APEVVNRRGHTQSADWWSFGVLMFEMLTGTLP 267 Score = 41.6 bits (96), Expect = 0.001 Identities = 29/103 (28%), Positives = 46/103 (44%), Gaps = 8/103 (7%) Frame = +1 Query: 157 SAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSY----EARVSDHGLPTLV----GP 312 SA+ + V ++H+ G H ++K SN+L R+ D G + G Sbjct: 517 SAVLFTITKTVEYLHAQGVV--HRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGL 574 Query: 313 SFSPTRVSGYRAPEVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 +P + + APEV + D++S GVLL +LTG P Sbjct: 575 LMTPCYTANFVAPEVLKRQGYDAACDIWSLGVLLYTMLTGYTP 617
>KS6A3_HUMAN (P51812) Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1)| (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protei Length = 740 Score = 48.9 bits (115), Expect = 6e-06 Identities = 32/92 (34%), Positives = 49/92 (53%), Gaps = 4/92 (4%) Frame = +1 Query: 178 ARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLV----GPSFSPTRVSGYR 345 A + H+HS G + ++K N+LL + +++D GL ++S Y Sbjct: 178 ALALDHLHSLG--IIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYM 235 Query: 346 APEVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 APEV + R +Q AD +SFGVL+ E+LTG P Sbjct: 236 APEVVNRRGHTQSADWWSFGVLMFEMLTGTLP 267 Score = 41.6 bits (96), Expect = 0.001 Identities = 29/103 (28%), Positives = 46/103 (44%), Gaps = 8/103 (7%) Frame = +1 Query: 157 SAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSY----EARVSDHGLPTLV----GP 312 SA+ + V ++H+ G H ++K SN+L R+ D G + G Sbjct: 517 SAVLFTITKTVEYLHAQGVV--HRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGL 574 Query: 313 SFSPTRVSGYRAPEVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 +P + + APEV + D++S GVLL +LTG P Sbjct: 575 LMTPCYTANFVAPEVLKRQGYDAACDIWSLGVLLYTMLTGYTP 617
>MK11_HUMAN (Q15759) Mitogen-activated protein kinase 11 (EC 2.7.11.24)| (Mitogen-activated protein kinase p38 beta) (MAP kinase p38 beta) (p38b) (p38-2) (Stress-activated protein kinase 2) Length = 372 Score = 48.9 bits (115), Expect = 6e-06 Identities = 31/88 (35%), Positives = 46/88 (52%), Gaps = 2/88 (2%) Frame = +1 Query: 181 RGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPSFSP-TRVSGYRAPEV 357 RG+ +IHS G H ++K SNV + + E R+ D GL + YRAPE+ Sbjct: 144 RGLKYIHSAG--IIHRDLKPSNVAVNEDCELRILDFGLARQADEEMTGYVATRWYRAPEI 201 Query: 358 T-DIRRVSQKADVYSFGVLLLELLTGKA 438 + +Q D++S G ++ ELL GKA Sbjct: 202 MLNWMHYNQTVDIWSVGCIMAELLQGKA 229
>ANPRB_RAT (P16067) Atrial natriuretic peptide receptor B precursor (ANP-B)| (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor) Length = 1047 Score = 48.9 bits (115), Expect = 6e-06 Identities = 33/110 (30%), Positives = 58/110 (52%), Gaps = 9/110 (8%) Frame = +1 Query: 139 LDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTL---VG 309 LDW R ++ +G+A +H++ +SHG++KSSN ++ + +++D+GL + Sbjct: 615 LDWMFRYSLINDLVKGMAFLHNS-IISSHGSLKSSNCVVDSRFVLKITDYGLASFRSTAE 673 Query: 310 PSFSPTRVSG--YRAPEVTDIRRV----SQKADVYSFGVLLLELLTGKAP 441 P S + + APE+ + QKADVYSF ++L E+ P Sbjct: 674 PDDSHALYAKKLWTAPELLSGNPLPTTGMQKADVYSFAIILQEIALRSGP 723
>ANPRB_MOUSE (Q6VVW5) Atrial natriuretic peptide receptor B precursor (ANP-B)| (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor) Length = 1047 Score = 48.9 bits (115), Expect = 6e-06 Identities = 33/110 (30%), Positives = 58/110 (52%), Gaps = 9/110 (8%) Frame = +1 Query: 139 LDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTL---VG 309 LDW R ++ +G+A +H++ +SHG++KSSN ++ + +++D+GL + Sbjct: 615 LDWMFRYSLINDLVKGMAFLHNS-IISSHGSLKSSNCVVDSRFVLKITDYGLASFRSTAE 673 Query: 310 PSFSPTRVSG--YRAPEVTDIRRV----SQKADVYSFGVLLLELLTGKAP 441 P S + + APE+ + QKADVYSF ++L E+ P Sbjct: 674 PDDSHALYAKKLWTAPELLSGNPLPTTGMQKADVYSFAIILQEIALRSGP 723
>MK11_MOUSE (Q9WUI1) Mitogen-activated protein kinase 11 (EC 2.7.11.24)| (Mitogen-activated protein kinase p38 beta) (MAP kinase p38 beta) (p38B) Length = 364 Score = 48.9 bits (115), Expect = 6e-06 Identities = 31/88 (35%), Positives = 46/88 (52%), Gaps = 2/88 (2%) Frame = +1 Query: 181 RGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPSFSP-TRVSGYRAPEV 357 RG+ +IHS G H ++K SNV + + E R+ D GL + YRAPE+ Sbjct: 136 RGLKYIHSAG--IIHRDLKPSNVAVNEDCELRILDFGLAPQADEEMTGYVATRWYRAPEI 193 Query: 358 T-DIRRVSQKADVYSFGVLLLELLTGKA 438 + +Q D++S G ++ ELL GKA Sbjct: 194 MLNWMHYNQTVDIWSVGCIMAELLQGKA 221
>KS6AA_CHICK (P18652) Ribosomal protein S6 kinase 2 alpha (EC 2.7.11.1)| (Ribosomal protein S6 kinase II alpha) (S6KII-alpha) (P90-RSK) (MAP kinase-activated protein kinase 1) (MAPK-activated protein kinase 1) (MAPKAP kinase 1) (MAPKAPK-1) Length = 752 Score = 48.9 bits (115), Expect = 6e-06 Identities = 31/92 (33%), Positives = 49/92 (53%), Gaps = 4/92 (4%) Frame = +1 Query: 178 ARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLV----GPSFSPTRVSGYR 345 A G+ H+HS G + ++K N+LL + +++D GL ++S Y Sbjct: 190 ALGLDHLHSLG--IIYRDLKPENILLDEEGHIKLTDFGLSKEAIDHEKKAYSFCGTVEYM 247 Query: 346 APEVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 APEV + + S AD +S+GVL+ E+LTG P Sbjct: 248 APEVVNRQGHSHSADWWSYGVLMFEMLTGSLP 279 Score = 38.9 bits (89), Expect = 0.006 Identities = 28/103 (27%), Positives = 46/103 (44%), Gaps = 8/103 (7%) Frame = +1 Query: 157 SAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSY----EARVSDHGLPTLV----GP 312 S++ + V ++HS G H ++K SN+L R+ D G + G Sbjct: 530 SSVLHTICKTVEYLHSQGVV--HRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGL 587 Query: 313 SFSPTRVSGYRAPEVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 +P + + APEV + + D++S GVLL +L G P Sbjct: 588 LMTPCYTANFVAPEVLKRQGYDEGCDIWSLGVLLYTMLAGCTP 630
>STE20_CANAL (Q92212) Serine/threonine-protein kinase STE20 homolog (EC 2.7.11.1)| Length = 1230 Score = 48.9 bits (115), Expect = 6e-06 Identities = 29/93 (31%), Positives = 48/93 (51%), Gaps = 4/93 (4%) Frame = +1 Query: 175 TARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPSFSP--TRVSG--Y 342 T +G+ +HS G H +IKS N+LL +++D G + S T V + Sbjct: 1057 TLKGLKFLHSKG--VIHRDIKSDNILLNMDGNIKITDFGFCAQINEINSKRITMVGTPYW 1114 Query: 343 RAPEVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 APE+ + K DV+S G++++E+L G+ P Sbjct: 1115 MAPEIVSRKEYGPKVDVWSLGIMIIEMLEGEPP 1147
>KS6AA_XENLA (P10665) Ribosomal protein S6 kinase 2 alpha (EC 2.7.11.1)| (Ribosomal protein S6 kinase II alpha) (S6KII-alpha) (P90-RSK) (MAP kinase-activated protein kinase 1) (MAPK-activated protein kinase 1) (MAPKAP kinase 1) (MAPKAPK-1) Length = 733 Score = 48.9 bits (115), Expect = 6e-06 Identities = 31/92 (33%), Positives = 49/92 (53%), Gaps = 4/92 (4%) Frame = +1 Query: 178 ARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLV----GPSFSPTRVSGYR 345 A G+ H+HS G + ++K N+LL + +++D GL ++S Y Sbjct: 172 ALGLDHLHSLG--IIYRDLKPENILLDEEGHIKLTDFGLSKEAIDHEKKAYSFCGTVEYM 229 Query: 346 APEVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 APEV + + S AD +S+GVL+ E+LTG P Sbjct: 230 APEVVNRQGHSHSADWWSYGVLMFEMLTGSLP 261 Score = 40.0 bits (92), Expect = 0.003 Identities = 27/103 (26%), Positives = 46/103 (44%), Gaps = 8/103 (7%) Frame = +1 Query: 157 SAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSY----EARVSDHGLPTLV----GP 312 S++ + V ++HS G H ++K SN+L R+ D G + G Sbjct: 511 SSVLFTVCKTVENLHSQGVV--HRDLKPSNILYVDESGDPESIRICDFGFAKQLRADNGL 568 Query: 313 SFSPTRVSGYRAPEVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 +P + + APEV + + D++S G+LL +L G P Sbjct: 569 LMTPCYTANFVAPEVLKRQGYDEGCDIWSLGILLYTMLAGYTP 611
>KS6A1_HUMAN (Q15418) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1)| (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 735 Score = 48.9 bits (115), Expect = 6e-06 Identities = 31/92 (33%), Positives = 49/92 (53%), Gaps = 4/92 (4%) Frame = +1 Query: 178 ARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLV----GPSFSPTRVSGYR 345 A G+ H+HS G + ++K N+LL + +++D GL ++S Y Sbjct: 172 ALGLDHLHSLG--IIYRDLKPENILLDEEGHIKLTDFGLSKEAIDHEKKAYSFCGTVEYM 229 Query: 346 APEVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 APEV + + S AD +S+GVL+ E+LTG P Sbjct: 230 APEVVNRQGHSHSADWWSYGVLMFEMLTGSLP 261 Score = 37.4 bits (85), Expect = 0.019 Identities = 29/107 (27%), Positives = 48/107 (44%), Gaps = 9/107 (8%) Frame = +1 Query: 148 EARSAIALAT-ARGVAHIHSTGPTASHGNIKSSNVLLTKSYE----ARVSDHGLPTLV-- 306 E ++ L T + V ++HS G H ++K SN+L R+ D G + Sbjct: 509 EREASFVLHTIGKTVEYLHSQGVV--HRDLKPSNILYVDESGNPECLRICDFGFAKQLRA 566 Query: 307 --GPSFSPTRVSGYRAPEVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 G +P + + APEV + + D++S G+LL +L G P Sbjct: 567 ENGLLMTPCYTANFVAPEVLKRQGYDEGCDIWSLGILLYTMLAGYTP 613
>MATK_MOUSE (P41242) Megakaryocyte-associated tyrosine-protein kinase (EC| 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK) Length = 505 Score = 48.9 bits (115), Expect = 6e-06 Identities = 33/94 (35%), Positives = 52/94 (55%), Gaps = 2/94 (2%) Frame = +1 Query: 166 ALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPSFSPTRVS-GY 342 AL A G+ ++ S H ++ + N+L+++ A+VSD GL +R+ + Sbjct: 331 ALHVAEGMEYLESK--KLVHRDLAARNILVSEDLVAKVSDFGLAKAERKGLDSSRLPVKW 388 Query: 343 RAPEVTDIRRVSQKADVYSFGVLLLELLT-GKAP 441 APE R S K+DV+SFGVLL E+ + G+AP Sbjct: 389 TAPEALKNGRFSSKSDVWSFGVLLWEVFSYGRAP 422
>PKNA2_BIFLO (Q8G4G1) Probable serine/threonine-protein kinase pknA2 (EC| 2.7.11.1) Length = 757 Score = 48.5 bits (114), Expect = 8e-06 Identities = 29/98 (29%), Positives = 49/98 (50%), Gaps = 5/98 (5%) Frame = +1 Query: 163 IALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPS-FSPTRV-- 333 + T G+A H G H +IK N+L+ +++D GL + S T + Sbjct: 120 VVAETLDGLASAHRAGVV--HRDIKPENILINDRGHVQITDFGLAKAASQATLSSTGMLL 177 Query: 334 --SGYRAPEVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 + Y APE+ + + + + D+YS G++ E+LTGK P Sbjct: 178 GTAAYLAPEMIENNQATAQGDLYSVGIMAWEMLTGKVP 215
>STK6_HUMAN (O14965) Serine/threonine-protein kinase 6 (EC 2.7.11.1)| (Serine/threonine kinase 15) (Aurora/IPL1-related kinase 1) (Aurora-related kinase 1) (hARK1) (Aurora-A) (Breast-tumor-amplified kinase) Length = 403 Score = 48.5 bits (114), Expect = 8e-06 Identities = 34/110 (30%), Positives = 54/110 (49%), Gaps = 3/110 (2%) Frame = +1 Query: 130 LTPLDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVG 309 L+ D + + A +++ HS H +IK N+LL + E +++D G ++ Sbjct: 225 LSKFDEQRTATYITELANALSYCHSK--RVIHRDIKPENLLLGSAGELKIADFGW-SVHA 281 Query: 310 PSFSPTRVSG---YRAPEVTDIRRVSQKADVYSFGVLLLELLTGKAPTHA 450 PS T + G Y PE+ + R +K D++S GVL E L GK P A Sbjct: 282 PSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEA 331
>PKNL_MYCTU (O53510) Probable serine/threonine-protein kinase pknL (EC| 2.7.11.1) Length = 399 Score = 48.5 bits (114), Expect = 8e-06 Identities = 34/107 (31%), Positives = 52/107 (48%), Gaps = 5/107 (4%) Frame = +1 Query: 136 PLDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGP- 312 P+ A A+ G+A H G H ++K N+L++ + +++D GL V Sbjct: 113 PMPPHAVVAVLRPVLGGLAAAHRAGLV--HRDVKPENILISDDGDVKLADFGLVRAVAAA 170 Query: 313 SFSPTRV----SGYRAPEVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 S + T V + Y +PE ++DVYS GVL+ ELLTG P Sbjct: 171 SITSTGVILGTAAYLSPEQVRDGNADPRSDVYSVGVLVYELLTGHTP 217
>PKNL_MYCBO (Q7TYY6) Probable serine/threonine-protein kinase pknL (EC| 2.7.11.1) Length = 399 Score = 48.5 bits (114), Expect = 8e-06 Identities = 34/107 (31%), Positives = 52/107 (48%), Gaps = 5/107 (4%) Frame = +1 Query: 136 PLDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGP- 312 P+ A A+ G+A H G H ++K N+L++ + +++D GL V Sbjct: 113 PMPPHAVVAVLRPVLGGLAAAHRAGLV--HRDVKPENILISDDGDVKLADFGLVRAVAAA 170 Query: 313 SFSPTRV----SGYRAPEVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 S + T V + Y +PE ++DVYS GVL+ ELLTG P Sbjct: 171 SITSTGVILGTAAYLSPEQVRDGNADPRSDVYSVGVLVYELLTGHTP 217
>PAK7_HUMAN (Q9P286) Serine/threonine-protein kinase PAK 7 (EC 2.7.11.1)| (p21-activated kinase 7) (PAK-7) (PAK-5) Length = 719 Score = 48.5 bits (114), Expect = 8e-06 Identities = 30/108 (27%), Positives = 56/108 (51%), Gaps = 5/108 (4%) Frame = +1 Query: 133 TPLDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGP 312 T ++ E + + L+ R ++++H+ G H +IKS ++LLT ++SD G V Sbjct: 538 TRMNEEQIATVCLSVLRALSYLHNQG--VIHRDIKSDSILLTSDGRIKLSDFGFCAQVSK 595 Query: 313 SFSPTRVS-----GYRAPEVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 P R S + APEV + D++S G++++E++ G+ P Sbjct: 596 EV-PKRKSLVGTPYWMAPEVISRLPYGTEVDIWSLGIMVIEMIDGEPP 642
>CLA4_CANAL (O14427) Serine/threonine-protein kinase CLA4 (EC 2.7.11.1)| Length = 971 Score = 48.5 bits (114), Expect = 8e-06 Identities = 30/106 (28%), Positives = 50/106 (47%), Gaps = 11/106 (10%) Frame = +1 Query: 157 SAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGL-----------PTL 303 + I T +G+ H+H H +IKS NVLL +++D G T+ Sbjct: 781 ATICFETLKGLQHLHKKH--IIHRDIKSDNVLLDAYGNVKITDFGFCAKLTDQRNKRATM 838 Query: 304 VGPSFSPTRVSGYRAPEVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 VG + + APEV + +K DV+S G++ +E++ G+ P Sbjct: 839 VGTPY-------WMAPEVVKQKEYDEKVDVWSLGIMTIEMIEGEPP 877
>ARAF_PIG (O19004) A-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (A-Raf-1) Length = 606 Score = 48.5 bits (114), Expect = 8e-06 Identities = 32/102 (31%), Positives = 54/102 (52%), Gaps = 9/102 (8%) Frame = +1 Query: 163 IALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTL------VGPSFSP 324 +A TA+G+ ++H+ H ++KS+N+ L + ++ D GL T+ P P Sbjct: 409 VARQTAQGMDYLHAKN--IIHRDLKSNNIFLHEGLTVKIGDFGLATVKTRWSGAQPLEQP 466 Query: 325 TRVSGYRAPEVT---DIRRVSQKADVYSFGVLLLELLTGKAP 441 + + A EV D S ++DVY++GV+L EL+TG P Sbjct: 467 SGSVLWMAAEVIRMQDPNPYSFQSDVYAYGVVLYELMTGSLP 508
>ARAF_HUMAN (P10398) A-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (A-raf-1) (Proto-oncogene Pks) Length = 606 Score = 48.5 bits (114), Expect = 8e-06 Identities = 32/102 (31%), Positives = 54/102 (52%), Gaps = 9/102 (8%) Frame = +1 Query: 163 IALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTL------VGPSFSP 324 +A TA+G+ ++H+ H ++KS+N+ L + ++ D GL T+ P P Sbjct: 409 VARQTAQGMDYLHAKN--IIHRDLKSNNIFLHEGLTVKIGDFGLATVKTRWSGAQPLEQP 466 Query: 325 TRVSGYRAPEVT---DIRRVSQKADVYSFGVLLLELLTGKAP 441 + + A EV D S ++DVY++GV+L EL+TG P Sbjct: 467 SGSVLWMAAEVIRMQDPNPYSFQSDVYAYGVVLYELMTGSLP 508
>ARAF_RAT (P14056) A-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) Length = 604 Score = 48.5 bits (114), Expect = 8e-06 Identities = 32/102 (31%), Positives = 54/102 (52%), Gaps = 9/102 (8%) Frame = +1 Query: 163 IALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTL------VGPSFSP 324 +A TA+G+ ++H+ H ++KS+N+ L + ++ D GL T+ P P Sbjct: 407 VARQTAQGMDYLHAKN--IIHRDLKSNNIFLHEGLTVKIGDFGLATVKTRWSGAQPLEQP 464 Query: 325 TRVSGYRAPEVT---DIRRVSQKADVYSFGVLLLELLTGKAP 441 + + A EV D S ++DVY++GV+L EL+TG P Sbjct: 465 SGSVLWMAAEVIRMQDPNPYSFQSDVYAYGVVLYELMTGSLP 506
>ARAF_MOUSE (P04627) A-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) Length = 604 Score = 48.5 bits (114), Expect = 8e-06 Identities = 32/102 (31%), Positives = 54/102 (52%), Gaps = 9/102 (8%) Frame = +1 Query: 163 IALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTL------VGPSFSP 324 +A TA+G+ ++H+ H ++KS+N+ L + ++ D GL T+ P P Sbjct: 407 VARQTAQGMDYLHAKN--IIHRDLKSNNIFLHEGLTVKIGDFGLATVKTRWSGAQPLEQP 464 Query: 325 TRVSGYRAPEVT---DIRRVSQKADVYSFGVLLLELLTGKAP 441 + + A EV D S ++DVY++GV+L EL+TG P Sbjct: 465 SGSVLWMAAEVIRMQDPNPYSFQSDVYAYGVVLYELMTGSLP 506
>PKN2_MYXXA (P54736) Serine/threonine-protein kinase pkn2 (EC 2.7.11.1)| Length = 830 Score = 48.5 bits (114), Expect = 8e-06 Identities = 33/99 (33%), Positives = 51/99 (51%), Gaps = 11/99 (11%) Frame = +1 Query: 178 ARGVAHIHSTGPTASHGNIKSSNVLLTKSY---EARVSDHGLPTLVGPSFSPT------- 327 A G+A IH G H ++K NV ++KS +AR+ D G+ LV P + + Sbjct: 120 AEGLAAIHDKG--IIHRDLKPENVFISKSARGEQARLLDFGIARLVEPDAASSVSQIGVV 177 Query: 328 -RVSGYRAPEVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 Y +PE +V ++D+YSFGVL +L+G+ P Sbjct: 178 LGTPEYLSPEQAVGAKVDTRSDLYSFGVLTYRVLSGRLP 216
>M3KL4_HUMAN (Q5TCX8) Mitogen-activated protein kinase kinase kinase (EC| 2.7.11.25) (Mixed lineage kinase 4) Length = 1036 Score = 48.5 bits (114), Expect = 8e-06 Identities = 34/107 (31%), Positives = 54/107 (50%), Gaps = 11/107 (10%) Frame = +1 Query: 166 ALATARGVAHIHSTG-PTASHGNIKSSNVLLTKSYE--------ARVSDHGLPTLVGPSF 318 A+ ARG+ ++H H ++KSSN+LL + E +++D GL + Sbjct: 241 AVQIARGMLYLHEEAFVPILHRDLKSSNILLLEKIEHDDICNKTLKITDFGLAREWHRTT 300 Query: 319 SPTRVSGYR--APEVTDIRRVSQKADVYSFGVLLLELLTGKAPTHAV 453 + Y APEV S+ +D++S+GVLL ELLTG+ P + Sbjct: 301 KMSTAGTYAWMAPEVIKSSLFSKGSDIWSYGVLLWELLTGEVPYRGI 347
>GUC2D_BOVIN (P55203) Retinal guanylyl cyclase 1 precursor (EC 4.6.1.2)| (Guanylate cyclase 2D, retinal) (RETGC-1) (Rod outer segment membrane guanylate cyclase) (ROS-GC) (Guanylate cyclase E) (GC-E) Length = 1110 Score = 48.5 bits (114), Expect = 8e-06 Identities = 32/110 (29%), Positives = 55/110 (50%), Gaps = 9/110 (8%) Frame = +1 Query: 139 LDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTL----- 303 LDW +S++ L +G+ ++H G +HG +KS N ++ + +V+DHG L Sbjct: 643 LDWMFKSSLLLDLIKGIRYLHHRG--VAHGRLKSRNCVVDGRFVLKVTDHGHGRLLEAQR 700 Query: 304 VGPSFSPTRVSGYRAPEVTD----IRRVSQKADVYSFGVLLLELLTGKAP 441 V P + APE+ RR + DV+S G+++ E++ AP Sbjct: 701 VLPEPPSAEDQLWTAPELLRDPVLERRGTLAGDVFSLGIIMQEVVCRSAP 750
>TAOK3_RAT (Q53UA7) Serine/threonine-protein kinase TAO3 (EC 2.7.11.1)| (Thousand and one amino acid protein 3) (Jun kinase-inhibitory kinase) (JNK/SAPK-inhibitory kinase) (Axotomy-related gene 357 protein) Length = 898 Score = 48.5 bits (114), Expect = 8e-06 Identities = 31/105 (29%), Positives = 54/105 (51%), Gaps = 3/105 (2%) Frame = +1 Query: 136 PLDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPS 315 PL +AI +G+A++H + H +IK+ N+LLT+ + +++D G ++ P+ Sbjct: 118 PLQEVEIAAITHGALQGLAYLHFH--SLIHRDIKAGNILLTEPGQVKLADFGSASMASPA 175 Query: 316 FSPTRVSGYRAPEV---TDIRRVSQKADVYSFGVLLLELLTGKAP 441 S + APEV D + K D++S G+ +EL K P Sbjct: 176 NSFVGTPYWMAPEVILAMDEGQYDGKVDIWSLGITCIELAERKPP 220
>TAOK3_MOUSE (Q8BYC6) Serine/threonine-protein kinase TAO3 (EC 2.7.11.1)| (Thousand and one amino acid protein 3) Length = 898 Score = 48.5 bits (114), Expect = 8e-06 Identities = 31/105 (29%), Positives = 54/105 (51%), Gaps = 3/105 (2%) Frame = +1 Query: 136 PLDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPS 315 PL +AI +G+A++H + H +IK+ N+LLT+ + +++D G ++ P+ Sbjct: 118 PLQEVEIAAITHGALQGLAYLHFH--SLIHRDIKAGNILLTEPGQVKLADFGSASMASPA 175 Query: 316 FSPTRVSGYRAPEV---TDIRRVSQKADVYSFGVLLLELLTGKAP 441 S + APEV D + K D++S G+ +EL K P Sbjct: 176 NSFVGTPYWMAPEVILAMDEGQYDGKVDIWSLGITCIELAERKPP 220
>MP2K2_XENLA (Q07192) Dual specificity mitogen-activated protein kinase kinase 2| (EC 2.7.12.2) (MAP kinase kinase 2) (MAPKK 2) (MAPK-ERK kinase 2) (Fragment) Length = 446 Score = 48.1 bits (113), Expect = 1e-05 Identities = 35/105 (33%), Positives = 52/105 (49%), Gaps = 7/105 (6%) Frame = +1 Query: 148 EARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPSFSPT 327 E I LAT + + H+ H +IK SN+LL + ++ D G+ + S + T Sbjct: 250 EILGKITLATVKALNHLKENLKII-HRDIKPSNILLDTNGNIKLCDFGISGQLVDSIAKT 308 Query: 328 RVSG---YRAPEVTDIRRVSQ----KADVYSFGVLLLELLTGKAP 441 R +G Y APE D Q ++DV+S G+ L EL TG+ P Sbjct: 309 RDAGCRPYMAPERIDPSASRQGYDVRSDVWSLGITLYELATGRFP 353
>YX05_CAEEL (Q11112) Putative tyrosine-protein kinase C03B1.5 in chromosome X| (EC 2.7.10.2) Length = 328 Score = 48.1 bits (113), Expect = 1e-05 Identities = 30/92 (32%), Positives = 48/92 (52%), Gaps = 9/92 (9%) Frame = +1 Query: 193 HIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPSFSPTRVS---------GYR 345 HIH+ G HG++ N+L+T ++SD G+ +F TR S G+ Sbjct: 145 HIHNLGIV--HGDLSVKNILMTHEGVVKLSDFGMAN----TFEQTRKSKNQSILGTPGFI 198 Query: 346 APEVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 APE+ +++ KAD++ G+L L LL G+ P Sbjct: 199 APEIINLQGYDGKADLWGLGILSLFLLKGENP 230
>KS6AB_XENLA (P10666) Ribosomal protein S6 kinase 2 beta (EC 2.7.11.1)| (Ribosomal protein S6 kinase II beta) (S6KII-beta) (P90-RSK) Length = 629 Score = 48.1 bits (113), Expect = 1e-05 Identities = 31/92 (33%), Positives = 49/92 (53%), Gaps = 4/92 (4%) Frame = +1 Query: 178 ARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLV----GPSFSPTRVSGYR 345 A G+ H+HS G + ++K N+LL + +++D GL ++S Y Sbjct: 172 ALGLDHLHSLG--IIYRDLKPENILLDEEGHIKLTDFGLSKEAIDHEKKAYSFCGTVEYM 229 Query: 346 APEVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 APEV + + S AD +S+GVL+ E+LTG P Sbjct: 230 APEVVNRQGHSHGADWWSYGVLMFEMLTGSLP 261 Score = 38.9 bits (89), Expect = 0.006 Identities = 26/102 (25%), Positives = 45/102 (44%), Gaps = 8/102 (7%) Frame = +1 Query: 160 AIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSY----EARVSDHGLPTLV----GPS 315 ++ + V ++HS G H ++K SN+L R+ D G + G Sbjct: 512 SVLFTVCKTVEYLHSQGVV--HRDLKPSNILYVDESGDPESIRICDFGFSKQLRAENGLL 569 Query: 316 FSPTRVSGYRAPEVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 +P + + APEV + + D++S G+LL +L G P Sbjct: 570 MTPCYTANFVAPEVLKRQGYDEGCDIWSLGILLYTMLAGYTP 611
>NRKA_TRYBB (Q08942) Putative serine/threonine-protein kinase A (EC 2.7.11.1)| Length = 431 Score = 48.1 bits (113), Expect = 1e-05 Identities = 32/84 (38%), Positives = 48/84 (57%), Gaps = 8/84 (9%) Frame = +1 Query: 223 HGNIKSSNVLLTKSYEARVSDHG--------LPTLVGPSFSPTRVSGYRAPEVTDIRRVS 378 H +IKS+NVLLT + ++ D G + +V +F T Y APE+ + +R + Sbjct: 145 HRDIKSANVLLTSTGLVKLGDFGFSHQYEDTVSGVVASTFCGTPY--YLAPELWNNKRYN 202 Query: 379 QKADVYSFGVLLLELLTGKAPTHA 450 +KADV+S GVLL E++ K P A Sbjct: 203 KKADVWSLGVLLYEIMGMKKPFSA 226
>FYN_XENLA (P13406) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 536 Score = 48.1 bits (113), Expect = 1e-05 Identities = 32/99 (32%), Positives = 53/99 (53%), Gaps = 6/99 (6%) Frame = +1 Query: 163 IALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPSFSPTRVSG- 339 +A ARG+A+I H +++S+N+L+ +++D GL L+ + R Sbjct: 369 MAAQVARGMAYIERMNYI--HRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAK 426 Query: 340 ----YRAPEVTDIRRVSQKADVYSFGVLLLELLT-GKAP 441 + APE R + K+DV+SFG+LL EL+T G+ P Sbjct: 427 FPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVP 465
>JNK_SUBDO (Q966Y3) Stress-activated protein kinase JNK (EC 2.7.11.24)| Length = 361 Score = 48.1 bits (113), Expect = 1e-05 Identities = 28/101 (27%), Positives = 49/101 (48%), Gaps = 3/101 (2%) Frame = +1 Query: 139 LDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPSF 318 LD + S + G+ H+HS G H ++K SN+++ + ++ D GL +F Sbjct: 119 LDHDRMSYLLYQLLCGIKHLHSAG--IIHRDLKPSNIVVKEDCSLKILDFGLARTADQTF 176 Query: 319 SPTR---VSGYRAPEVTDIRRVSQKADVYSFGVLLLELLTG 432 + T YRAPEV + + D++S G + E++ G Sbjct: 177 NMTPYVVTRYYRAPEVIVGMKYKENVDIWSVGCIFAEMIRG 217
>WNK3_HUMAN (Q9BYP7) Serine/threonine-protein kinase WNK3 (EC 2.7.11.1)| (Protein kinase with no lysine 3) (Protein kinase, lysine-deficient 3) Length = 1743 Score = 48.1 bits (113), Expect = 1e-05 Identities = 26/90 (28%), Positives = 50/90 (55%), Gaps = 3/90 (3%) Frame = +1 Query: 181 RGVAHIHSTGPTASHGNIKSSNVLLT-KSYEARVSDHGLPTLVGPSFSPTRVSG--YRAP 351 +G+ +H+ P H ++K N+ +T + ++ D GL TL+ SF+ + + + AP Sbjct: 259 KGLQFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLMRTSFAKSVIGTPEFMAP 318 Query: 352 EVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 E+ + + DVY+FG+ +LE+ T + P Sbjct: 319 EMYE-EHYDESVDVYAFGMCMLEMATSEYP 347
>SRC42_DROME (Q9V9J3) Tyrosine-protein kinase Src42A (EC 2.7.10.2) (Dsrc41)| Length = 517 Score = 48.1 bits (113), Expect = 1e-05 Identities = 33/105 (31%), Positives = 54/105 (51%), Gaps = 6/105 (5%) Frame = +1 Query: 163 IALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPSFSPTRVSG- 339 +A A G+A++ S H ++ + NVL+ +++D GL L+ RV Sbjct: 350 MAAQIAAGMAYLESQNYI--HRDLAARNVLVGDGNIVKIADFGLARLIKEDEYEARVGAR 407 Query: 340 ----YRAPEVTDIRRVSQKADVYSFGVLLLELLT-GKAPTHAVVN 459 + APE + + S K+DV+SFG+LL EL+T G+ P + N Sbjct: 408 FPIKWTAPEAANYSKFSIKSDVWSFGILLTELVTYGRIPYPGMTN 452
>CDS1_SCHPO (Q09170) Serine/threonine-protein kinase cds1 (EC 2.7.11.1)| (Checkpoint kinase cds1) Length = 460 Score = 48.1 bits (113), Expect = 1e-05 Identities = 31/93 (33%), Positives = 47/93 (50%), Gaps = 10/93 (10%) Frame = +1 Query: 193 HIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLV--GPSFSPT--RVSGYRAPEVT 360 H+H G T H +IK N+L+T + ++SD GL ++ +F T GY APEV Sbjct: 284 HLHKQGVT--HRDIKPENILITNDFHLKISDFGLAKVIHGTGTFLETFCGTMGYLAPEVL 341 Query: 361 DIRRVS------QKADVYSFGVLLLELLTGKAP 441 + V+ K D++S G +L +LT P Sbjct: 342 KSKNVNLDGGYDDKVDIWSLGCVLYVMLTASIP 374
>WNK1_HUMAN (Q9H4A3) Serine/threonine-protein kinase WNK1 (EC 2.7.11.1)| (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein) Length = 2382 Score = 47.8 bits (112), Expect = 1e-05 Identities = 26/90 (28%), Positives = 50/90 (55%), Gaps = 3/90 (3%) Frame = +1 Query: 181 RGVAHIHSTGPTASHGNIKSSNVLLT-KSYEARVSDHGLPTLVGPSFSPTRVSG--YRAP 351 +G+ +H+ P H ++K N+ +T + ++ D GL TL SF+ + + + AP Sbjct: 333 KGLQFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRASFAKSVIGTPEFMAP 392 Query: 352 EVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 E+ + + + DVY+FG+ +LE+ T + P Sbjct: 393 EMYE-EKYDESVDVYAFGMCMLEMATSEYP 421
>PAK4_MOUSE (Q8BTW9) Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1)| (p21-activated kinase 4) (PAK-4) Length = 593 Score = 47.8 bits (112), Expect = 1e-05 Identities = 32/108 (29%), Positives = 56/108 (51%), Gaps = 5/108 (4%) Frame = +1 Query: 133 TPLDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGP 312 T ++ E +A+ LA + +A +H+ G H +IKS ++LLT ++SD G V Sbjct: 412 TRMNEEQIAAVCLAVLQALAVLHAQG--VIHRDIKSDSILLTHDGRVKLSDFGFCAQVSK 469 Query: 313 SFSPTRVS-----GYRAPEVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 P R S + APE+ + D++S GV+++E++ G+ P Sbjct: 470 EV-PRRKSLVGTPYWMAPELISRLPYGPEVDIWSLGVMVIEMVDGEPP 516
>SRC_HUMAN (P12931) Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2)| (p60-Src) (c-Src) (pp60c-src) Length = 535 Score = 47.8 bits (112), Expect = 1e-05 Identities = 32/105 (30%), Positives = 56/105 (53%), Gaps = 6/105 (5%) Frame = +1 Query: 163 IALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPSFSPTRVSG- 339 +A A G+A++ H +++++N+L+ ++ +V+D GL L+ + R Sbjct: 368 MAAQIASGMAYVERMNYV--HRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAK 425 Query: 340 ----YRAPEVTDIRRVSQKADVYSFGVLLLELLT-GKAPTHAVVN 459 + APE R + K+DV+SFG+LL EL T G+ P +VN Sbjct: 426 FPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVN 470
>KS6A1_RAT (Q63531) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1)| (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 735 Score = 47.8 bits (112), Expect = 1e-05 Identities = 30/92 (32%), Positives = 49/92 (53%), Gaps = 4/92 (4%) Frame = +1 Query: 178 ARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLV----GPSFSPTRVSGYR 345 A G+ H+HS G + ++K N+LL + +++D GL ++S Y Sbjct: 172 ALGLDHLHSLG--IIYRDLKPENILLDEEGHIKLTDFGLSKEAIDHEKKAYSFCGTVEYM 229 Query: 346 APEVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 APEV + + + AD +S+GVL+ E+LTG P Sbjct: 230 APEVVNRQGHTHSADWWSYGVLMFEMLTGSLP 261 Score = 38.5 bits (88), Expect = 0.008 Identities = 28/103 (27%), Positives = 46/103 (44%), Gaps = 8/103 (7%) Frame = +1 Query: 157 SAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYE----ARVSDHGLPTLV----GP 312 S + ++ V ++HS G H ++K SN+L R+ D G + G Sbjct: 513 SFVLYTISKTVEYLHSQGVV--HRDLKPSNILYVDESGNPECLRICDFGFAKQLRAENGL 570 Query: 313 SFSPTRVSGYRAPEVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 +P + + APEV + + D++S GVLL +L G P Sbjct: 571 LMTPCYTANFVAPEVLKRQGYDEGCDIWSLGVLLYTMLAGYTP 613
>SRC_RSVPA (P31693) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 522 Score = 47.8 bits (112), Expect = 1e-05 Identities = 32/105 (30%), Positives = 56/105 (53%), Gaps = 6/105 (5%) Frame = +1 Query: 163 IALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPSFSPTRVSG- 339 +A A G+A++ H +++++N+L+ ++ +V+D GL L+ + R Sbjct: 362 MAAQIASGMAYVERMNYV--HRDLRAANILVGENLVCKVADFGLARLIEDNEYTARPGAR 419 Query: 340 ----YRAPEVTDIRRVSQKADVYSFGVLLLELLT-GKAPTHAVVN 459 + APE R + K+DV+SFG+LL EL T G+ P +VN Sbjct: 420 FPVKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVN 464
>SRC2_XENLA (P13116) Tyrosine-protein kinase Src-2 (EC 2.7.10.2) (p60-Src-2)| Length = 531 Score = 47.8 bits (112), Expect = 1e-05 Identities = 32/105 (30%), Positives = 56/105 (53%), Gaps = 6/105 (5%) Frame = +1 Query: 163 IALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPSFSPTRVSG- 339 +A A G+A++ H +++++N+L+ ++ +V+D GL L+ + R Sbjct: 364 MAAQIASGMAYVERMNYV--HRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAK 421 Query: 340 ----YRAPEVTDIRRVSQKADVYSFGVLLLELLT-GKAPTHAVVN 459 + APE R + K+DV+SFG+LL EL T G+ P +VN Sbjct: 422 FPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVN 466
>SRC1_XENLA (P13115) Tyrosine-protein kinase Src-1 (EC 2.7.10.2) (p60-Src-1)| Length = 531 Score = 47.8 bits (112), Expect = 1e-05 Identities = 32/105 (30%), Positives = 56/105 (53%), Gaps = 6/105 (5%) Frame = +1 Query: 163 IALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPSFSPTRVSG- 339 +A A G+A++ H +++++N+L+ ++ +V+D GL L+ + R Sbjct: 364 MAAQIASGMAYVERMNYV--HRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAK 421 Query: 340 ----YRAPEVTDIRRVSQKADVYSFGVLLLELLT-GKAPTHAVVN 459 + APE R + K+DV+SFG+LL EL T G+ P +VN Sbjct: 422 FPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVN 466
>SRC_AVIST (P14085) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 556 Score = 47.8 bits (112), Expect = 1e-05 Identities = 32/105 (30%), Positives = 56/105 (53%), Gaps = 6/105 (5%) Frame = +1 Query: 163 IALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPSFSPTRVSG- 339 +A A G+A++ H +++++N+L+ ++ +V+D GL L+ + R Sbjct: 365 MAAQIASGMAYVERMNYV--HRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAK 422 Query: 340 ----YRAPEVTDIRRVSQKADVYSFGVLLLELLT-GKAPTHAVVN 459 + APE R + K+DV+SFG+LL EL T G+ P +VN Sbjct: 423 FPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVN 467
>SRC_RSVP (P00526) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 47.8 bits (112), Expect = 1e-05 Identities = 32/105 (30%), Positives = 56/105 (53%), Gaps = 6/105 (5%) Frame = +1 Query: 163 IALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPSFSPTRVSG- 339 +A A G+A++ H +++++N+L+ ++ +V+D GL L+ + R Sbjct: 365 MAAQIASGMAYVERMNYV--HRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAK 422 Query: 340 ----YRAPEVTDIRRVSQKADVYSFGVLLLELLT-GKAPTHAVVN 459 + APE R + K+DV+SFG+LL EL T G+ P +VN Sbjct: 423 FPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVN 467
>SRC_RSVH1 (P25020) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 47.8 bits (112), Expect = 1e-05 Identities = 32/105 (30%), Positives = 56/105 (53%), Gaps = 6/105 (5%) Frame = +1 Query: 163 IALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPSFSPTRVSG- 339 +A A G+A++ H +++++N+L+ ++ +V+D GL L+ + R Sbjct: 365 MAAQIASGMAYVERMNYV--HRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAK 422 Query: 340 ----YRAPEVTDIRRVSQKADVYSFGVLLLELLT-GKAPTHAVVN 459 + APE R + K+DV+SFG+LL EL T G+ P +VN Sbjct: 423 FPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVN 467
>MK10_MOUSE (Q61831) Mitogen-activated protein kinase 10 (EC 2.7.11.24)| (Stress-activated protein kinase JNK3) (c-Jun N-terminal kinase 3) (MAP kinase p49 3F12) Length = 464 Score = 47.8 bits (112), Expect = 1e-05 Identities = 31/102 (30%), Positives = 48/102 (47%), Gaps = 3/102 (2%) Frame = +1 Query: 139 LDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPSF 318 LD E S + G+ H+HS G H ++K SN+++ ++ D GL G SF Sbjct: 161 LDHERMSYLLYQMLCGIKHLHSAG--IIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF 218 Query: 319 SPTR---VSGYRAPEVTDIRRVSQKADVYSFGVLLLELLTGK 435 T YRAPEV + D++S G ++ E++ K Sbjct: 219 MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMVRHK 260
>MK10_HUMAN (P53779) Mitogen-activated protein kinase 10 (EC 2.7.11.24)| (Stress-activated protein kinase JNK3) (c-Jun N-terminal kinase 3) (MAP kinase p49 3F12) Length = 464 Score = 47.8 bits (112), Expect = 1e-05 Identities = 31/102 (30%), Positives = 48/102 (47%), Gaps = 3/102 (2%) Frame = +1 Query: 139 LDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPSF 318 LD E S + G+ H+HS G H ++K SN+++ ++ D GL G SF Sbjct: 161 LDHERMSYLLYQMLCGIKHLHSAG--IIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF 218 Query: 319 SPTR---VSGYRAPEVTDIRRVSQKADVYSFGVLLLELLTGK 435 T YRAPEV + D++S G ++ E++ K Sbjct: 219 MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMVRHK 260
>PKN5_MYXXA (P54737) Serine/threonine-protein kinase pkn5 (EC 2.7.11.1)| Length = 380 Score = 47.8 bits (112), Expect = 1e-05 Identities = 31/100 (31%), Positives = 48/100 (48%), Gaps = 6/100 (6%) Frame = +1 Query: 169 LATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPSFSPTRVSG--- 339 L +A+IH G H ++K SN+++ + R+ D GL + + T Sbjct: 226 LQICEALAYIHGHGLV--HRDLKPSNIMVDDDRQVRLMDFGLAKFLADDAAITEAGKLVG 283 Query: 340 ---YRAPEVTDIRRVSQKADVYSFGVLLLELLTGKAPTHA 450 Y APE + +AD+YS GV+L ELL+G+ P A Sbjct: 284 TYRYMAPEQILGEPLDGRADLYSLGVILYELLSGRPPFDA 323
>SRC_AVISS (P14084) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 567 Score = 47.8 bits (112), Expect = 1e-05 Identities = 32/105 (30%), Positives = 56/105 (53%), Gaps = 6/105 (5%) Frame = +1 Query: 163 IALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPSFSPTRVSG- 339 +A A G+A++ H +++++N+L+ ++ +V+D GL L+ + R Sbjct: 365 MAAQIASGMAYVERMNYV--HRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAK 422 Query: 340 ----YRAPEVTDIRRVSQKADVYSFGVLLLELLT-GKAPTHAVVN 459 + APE R + K+DV+SFG+LL EL T G+ P +VN Sbjct: 423 FPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVN 467
>WNK1_MOUSE (P83741) Serine/threonine-protein kinase WNK1 (EC 2.7.11.1)| (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) Length = 2377 Score = 47.8 bits (112), Expect = 1e-05 Identities = 26/90 (28%), Positives = 50/90 (55%), Gaps = 3/90 (3%) Frame = +1 Query: 181 RGVAHIHSTGPTASHGNIKSSNVLLT-KSYEARVSDHGLPTLVGPSFSPTRVSG--YRAP 351 +G+ +H+ P H ++K N+ +T + ++ D GL TL SF+ + + + AP Sbjct: 333 KGLQFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRASFAKSVIGTPEFMAP 392 Query: 352 EVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 E+ + + + DVY+FG+ +LE+ T + P Sbjct: 393 EMYE-EKYDESVDVYAFGMCMLEMATSEYP 421
>ANKK1_HUMAN (Q8NFD2) Ankyrin repeat and protein kinase domain-containing| protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (X-kinase) (SgK288) Length = 765 Score = 47.8 bits (112), Expect = 1e-05 Identities = 33/111 (29%), Positives = 50/111 (45%), Gaps = 10/111 (9%) Frame = +1 Query: 139 LDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPSF 318 L W+ R I T+ + +HS P H ++K N+LL + ++SD GL + S Sbjct: 115 LCWKLRFRIIHETSLAMNFLHSIKPPLLHLDLKPGNILLDSNMHVKISDFGLSKWMEQST 174 Query: 319 SPTRVS--------GYRAPE--VTDIRRVSQKADVYSFGVLLLELLTGKAP 441 + Y PE + + K DVYSF +++ ELLT K P Sbjct: 175 RMQYIERSALRGMLSYIPPEMFLESNKAPGPKYDVYSFAIVIWELLTQKKP 225
>WNK1_RAT (Q9JIH7) Serine/threonine-protein kinase WNK1 (EC 2.7.11.1)| (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) Length = 2126 Score = 47.8 bits (112), Expect = 1e-05 Identities = 26/90 (28%), Positives = 50/90 (55%), Gaps = 3/90 (3%) Frame = +1 Query: 181 RGVAHIHSTGPTASHGNIKSSNVLLT-KSYEARVSDHGLPTLVGPSFSPTRVSG--YRAP 351 +G+ +H+ P H ++K N+ +T + ++ D GL TL SF+ + + + AP Sbjct: 333 KGLQFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRASFAKSVIGTPEFMAP 392 Query: 352 EVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 E+ + + + DVY+FG+ +LE+ T + P Sbjct: 393 EMYE-EKYDESVDVYAFGMCMLEMATSEYP 421
>TAOK3_XENLA (Q6DD27) Serine/threonine-protein kinase TAO3 (EC 2.7.11.1)| (Thousand and one amino acid protein 3) Length = 896 Score = 47.8 bits (112), Expect = 1e-05 Identities = 32/105 (30%), Positives = 53/105 (50%), Gaps = 3/105 (2%) Frame = +1 Query: 136 PLDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPS 315 PL +AI +G+A++HS H +IK+ N+LLT+ + +++D G + P+ Sbjct: 118 PLQEVEIAAITHGALQGLAYLHSHNMI--HRDIKAGNILLTEPGQVKLADFGSASKSSPA 175 Query: 316 FSPTRVSGYRAPEV---TDIRRVSQKADVYSFGVLLLELLTGKAP 441 S + APEV D + K D++S G+ +EL K P Sbjct: 176 NSFVGTPYWMAPEVILAMDEGQYDGKIDIWSLGITCIELAERKPP 220
>SRC_CHICK (P00523) Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2)| (p60-Src) (c-Src) (pp60c-src) Length = 532 Score = 47.8 bits (112), Expect = 1e-05 Identities = 32/105 (30%), Positives = 56/105 (53%), Gaps = 6/105 (5%) Frame = +1 Query: 163 IALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPSFSPTRVSG- 339 +A A G+A++ H +++++N+L+ ++ +V+D GL L+ + R Sbjct: 365 MAAQIASGMAYVERMNYV--HRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAK 422 Query: 340 ----YRAPEVTDIRRVSQKADVYSFGVLLLELLT-GKAPTHAVVN 459 + APE R + K+DV+SFG+LL EL T G+ P +VN Sbjct: 423 FPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVN 467
>SRC_AVIS2 (P15054) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 586 Score = 47.8 bits (112), Expect = 1e-05 Identities = 32/105 (30%), Positives = 56/105 (53%), Gaps = 6/105 (5%) Frame = +1 Query: 163 IALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPSFSPTRVSG- 339 +A A G+A++ H +++++N+L+ ++ +V+D GL L+ + R Sbjct: 365 MAAQIASGMAYVERMNYV--HRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAK 422 Query: 340 ----YRAPEVTDIRRVSQKADVYSFGVLLLELLT-GKAPTHAVVN 459 + APE R + K+DV+SFG+LL EL T G+ P +VN Sbjct: 423 FPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVN 467
>STK24_HUMAN (Q9Y6E0) Serine/threonine-protein kinase 24 (EC 2.7.11.1)| (STE20-like kinase MST3) (MST-3) (Mammalian STE20-like protein kinase 3) Length = 443 Score = 47.8 bits (112), Expect = 1e-05 Identities = 34/113 (30%), Positives = 54/113 (47%), Gaps = 11/113 (9%) Frame = +1 Query: 136 PLDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLP------ 297 PLD + I +G+ ++HS H +IK++NVLL++ E +++D G+ Sbjct: 127 PLDETQIATILREILKGLDYLHSEKKI--HRDIKAANVLLSEHGEVKLADFGVAGQLTDT 184 Query: 298 -----TLVGPSFSPTRVSGYRAPEVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 T VG F + APEV KAD++S G+ +EL G+ P Sbjct: 185 QIKRNTFVGTPF-------WMAPEVIKQSAYDSKADIWSLGITAIELARGEPP 230
>TAOK3_PONPY (Q5R4F3) Serine/threonine-protein kinase TAO3 (EC 2.7.11.1)| (Thousand and one amino acid protein 3) Length = 898 Score = 47.8 bits (112), Expect = 1e-05 Identities = 32/103 (31%), Positives = 52/103 (50%), Gaps = 3/103 (2%) Frame = +1 Query: 136 PLDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPS 315 PL +AI G+A++HS H +IK+ N+LLT+ + +++D G ++ P+ Sbjct: 118 PLQEVEIAAITHGALHGLAYLHSHA--LIHRDIKAGNILLTEPGQVKLADFGSASVASPA 175 Query: 316 FSPTRVSGYRAPEV---TDIRRVSQKADVYSFGVLLLELLTGK 435 S + APEV D + K DV+S G+ +EL K Sbjct: 176 NSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERK 218
>CHK1_SCHPO (P34208) Serine/threonine-protein kinase chk1 (EC 2.7.11.1)| (Checkpoint kinase 1) Length = 496 Score = 47.4 bits (111), Expect = 2e-05 Identities = 32/92 (34%), Positives = 48/92 (52%), Gaps = 6/92 (6%) Frame = +1 Query: 184 GVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLV---GPS---FSPTRVSGYR 345 G++ +HS G +H ++K N+LL + ++SD G +L G S SP Y Sbjct: 124 GISFMHSKG--VAHRDLKPENILLDYNGNLKISDFGFASLFSYKGKSRLLNSPVGSPPYA 181 Query: 346 APEVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 APE+T + K DV+S G++L LL G P Sbjct: 182 APEITQ-QYDGSKVDVWSCGIILFALLLGNTP 212
>STK6_RAT (P59241) Serine/threonine-protein kinase 6 (EC 2.7.11.1) (Aurora-A)| (ratAurA) Length = 397 Score = 47.4 bits (111), Expect = 2e-05 Identities = 33/110 (30%), Positives = 54/110 (49%), Gaps = 3/110 (2%) Frame = +1 Query: 130 LTPLDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVG 309 L+ D + + A +++ HS H +IK N+LL + E +++D G ++ Sbjct: 218 LSKFDEQRTATYITELANALSYCHSK--RVIHRDIKPENLLLGSNGELKIADFGW-SVHA 274 Query: 310 PSFSPTRVSG---YRAPEVTDIRRVSQKADVYSFGVLLLELLTGKAPTHA 450 PS T + G Y+ PE+ + R +K D++S GVL E L G P A Sbjct: 275 PSSRRTTLCGTLDYQPPEMIEGRMHDEKVDLWSLGVLCYEFLVGMPPFEA 324
>PAK7_MOUSE (Q8C015) Serine/threonine-protein kinase PAK 7 (EC 2.7.11.1)| (p21-activated kinase 7) (PAK-7) (p21-activated kinase 5) Length = 719 Score = 47.4 bits (111), Expect = 2e-05 Identities = 29/108 (26%), Positives = 56/108 (51%), Gaps = 5/108 (4%) Frame = +1 Query: 133 TPLDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGP 312 T ++ E + + L+ + ++++H+ G H +IKS ++LLT ++SD G V Sbjct: 538 TRMNEEQIATVCLSVLKALSYLHNQG--VIHRDIKSDSILLTSDGRIKLSDFGFCAQVSK 595 Query: 313 SFSPTRVS-----GYRAPEVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 P R S + APEV + D++S G++++E++ G+ P Sbjct: 596 EV-PKRKSLVGTPYWMAPEVISRLPYGTEVDIWSLGIMVIEMIDGEPP 642
>MLTK_MOUSE (Q9ESL4) Mitogen-activated protein kinase kinase kinase MLT (EC| 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper-and sterile alpha motif kinase ZAK) (Sterile alpha motif- and leucine zipper-containing kinase AZK) ( Length = 802 Score = 47.4 bits (111), Expect = 2e-05 Identities = 31/104 (29%), Positives = 50/104 (48%), Gaps = 3/104 (2%) Frame = +1 Query: 139 LDWEARSAIALATARGVAHIHSTGPT-ASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPS 315 +D E A A+G+ ++H P H ++KS NV++ ++ D G + Sbjct: 102 MDMEHIMTWATDVAKGMHYLHMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASRFHNHT 161 Query: 316 FSPTRVSGY--RAPEVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 + V + APEV VS+ D YS+GV+L E+LT + P Sbjct: 162 THMSLVGTFPWMAPEVIQSLPVSETCDTYSYGVVLWEMLTREVP 205
>LRRK1_HUMAN (Q38SD2) Leucine-rich repeat serine/threonine-protein kinase 1 (EC| 2.7.11.1) Length = 2038 Score = 47.0 bits (110), Expect = 2e-05 Identities = 37/125 (29%), Positives = 62/125 (49%), Gaps = 12/125 (9%) Frame = +1 Query: 103 VLAGN-RSSGLTPLDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLL-----TKS 264 VL+ N R S PL IA A G+A++H ++KS N+L+ + Sbjct: 1368 VLSENARDSSFIPLGHMLTQKIAYQIASGLAYLHKKNIIFC--DLKSDNILVWSLDVKEH 1425 Query: 265 YEARVSDHGLPT------LVGPSFSPTRVSGYRAPEVTDIRRVSQKADVYSFGVLLLELL 426 ++SD+G+ +G +P GY+APE+ +K D++S+G++L ELL Sbjct: 1426 INIKLSDYGISRQSFHEGALGVEGTP----GYQAPEIRPRIVYDEKVDMFSYGMVLYELL 1481 Query: 427 TGKAP 441 +G+ P Sbjct: 1482 SGQRP 1486
>MKK1_YEAST (P32490) MAP kinase kinase MKK1/SSP32 (EC 2.7.12.2)| Length = 508 Score = 47.0 bits (110), Expect = 2e-05 Identities = 31/95 (32%), Positives = 50/95 (52%), Gaps = 2/95 (2%) Frame = +1 Query: 163 IALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPSFSPT--RVS 336 IA A RG++++H H +IK N+LL ++ + ++ D G+ S + T S Sbjct: 329 IAEAVLRGLSYLHEK--KVIHRDIKPQNILLNENGQVKLCDFGVSGEAVNSLATTFTGTS 386 Query: 337 GYRAPEVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 Y APE + S +DV+S G+ +LE+ GK P Sbjct: 387 FYMAPERIQGQPYSVTSDVWSLGLTILEVANGKFP 421
>AMHR2_RAT (Q62893) Anti-Muellerian hormone type-2 receptor precursor (EC| 2.7.11.30) (Anti-Muellerian hormone type II receptor) (AMH type II receptor) (MIS type II receptor) (MISRII) (MRII) (C14) Length = 557 Score = 47.0 bits (110), Expect = 2e-05 Identities = 36/126 (28%), Positives = 57/126 (45%), Gaps = 30/126 (23%) Frame = +1 Query: 142 DWEARSAIALATARGVAHIHSTG-------PTASHGNIKSSNVLLTKSYEARVSDHGLPT 300 DW + +AL+ A G+A +H P +H ++ S NVL+ + + D GL Sbjct: 295 DWGSSLRMALSLAEGLAFLHGERWQDGQYKPGIAHRDLSSQNVLIREDRSCAIGDLGLAL 354 Query: 301 LVG-----PSFSPTRVSG-----------YRAPEVTDIR-------RVSQKADVYSFGVL 411 ++ P+ +PT+ G Y APE+ D Q+ADVYS +L Sbjct: 355 VLPGLAQPPALAPTQPRGPAAILEAGTQRYMAPELLDKTLDLQDWGTALQRADVYSLALL 414 Query: 412 LLELLT 429 L E+L+ Sbjct: 415 LWEILS 420
>CDC7_SCHPO (P41892) Cell division control protein 7 (EC 2.7.11.1)| Length = 1062 Score = 47.0 bits (110), Expect = 2e-05 Identities = 26/89 (29%), Positives = 49/89 (55%), Gaps = 2/89 (2%) Frame = +1 Query: 181 RGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPSFSPTRVSG--YRAPE 354 +G+ ++H+ G H +IK +N+L TK +++D G+ T + + V + APE Sbjct: 117 QGLLYLHNQG--VIHRDIKGANILTTKDGTIKLADFGVATKINALEDHSVVGSPYWMAPE 174 Query: 355 VTDIRRVSQKADVYSFGVLLLELLTGKAP 441 V ++ + +D++S G ++ELL G P Sbjct: 175 VIELVGATTASDIWSVGCTVIELLDGNPP 203
>JNK_DROME (P92208) Stress-activated protein kinase JNK (EC 2.7.11.24) (dJNK)| (Protein basket) Length = 372 Score = 47.0 bits (110), Expect = 2e-05 Identities = 29/101 (28%), Positives = 49/101 (48%), Gaps = 3/101 (2%) Frame = +1 Query: 139 LDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPSF 318 LD + S + G+ H+HS G H ++K SN+++ ++ D GL G +F Sbjct: 121 LDHDRMSYLLYQMLCGIKHLHSAG--IIHRDLKPSNIVVKADCTLKILDFGLARTAGTTF 178 Query: 319 SPTR---VSGYRAPEVTDIRRVSQKADVYSFGVLLLELLTG 432 T YRAPEV ++ D++S G ++ E++ G Sbjct: 179 MMTPYVVTRYYRAPEVILGMGYTENVDIWSVGCIMGEMIRG 219
>PKNX_STRCO (Q9XA16) Probable serine/threonine-protein kinase SCO3848 (EC| 2.7.11.1) Length = 673 Score = 47.0 bits (110), Expect = 2e-05 Identities = 28/80 (35%), Positives = 46/80 (57%), Gaps = 7/80 (8%) Frame = +1 Query: 223 HGNIKSSNVLLTKSYEARVSDHGLPTLVGPS-FSPTRVSG------YRAPEVTDIRRVSQ 381 H +IK +NV+LT++ + +V D G+ +G S + T+ + Y +PE +V Sbjct: 136 HRDIKPANVMLTRNGQVKVMDFGIARAMGDSGMTMTQTAAVIGTAQYLSPEQAKGEQVDA 195 Query: 382 KADVYSFGVLLLELLTGKAP 441 ++D+YS G LL ELLT + P Sbjct: 196 RSDLYSTGCLLYELLTVRPP 215
>M3K7_MOUSE (Q62073) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1) Length = 579 Score = 47.0 bits (110), Expect = 2e-05 Identities = 30/94 (31%), Positives = 52/94 (55%), Gaps = 3/94 (3%) Frame = +1 Query: 169 LATARGVAHIHSTGPTAS-HGNIKSSNVLLTKSYEA-RVSDHGLPTLVGPSFSPTRVSG- 339 L ++GVA++HS P A H ++K N+LL ++ D G + + + S Sbjct: 135 LQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGTVLKICDFGTACDIQTHMTNNKGSAA 194 Query: 340 YRAPEVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 + APEV + S+K DV+S+G++L E++T + P Sbjct: 195 WMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKP 228
>RIPK5_XENLA (Q67E01) Receptor-interacting serine/threonine-protein kinase 5 (EC| 2.7.11.1) (Dusty protein kinase) (Dusty PK) Length = 916 Score = 47.0 bits (110), Expect = 2e-05 Identities = 33/103 (32%), Positives = 51/103 (49%), Gaps = 3/103 (2%) Frame = +1 Query: 133 TPLDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGL---PTL 303 T L E R IAL G+ +H+ G H +IK NVLL K + A+++D G + Sbjct: 736 TGLSLETRLQIALDVVEGIRFLHNQGVV--HRDIKLKNVLLDKKHRAKITDLGFCKPEAM 793 Query: 304 VGPSFSPTRVSGYRAPEVTDIRRVSQKADVYSFGVLLLELLTG 432 + S T + + APE+ + DVY+FG+L + +G Sbjct: 794 MSGSIVGTPI--HMAPELFS-GKYDNSVDVYAFGILFWYICSG 833
>MK08_HUMAN (P45983) Mitogen-activated protein kinase 8 (EC 2.7.11.24)| (Stress-activated protein kinase JNK1) (c-Jun N-terminal kinase 1) (JNK-46) Length = 427 Score = 47.0 bits (110), Expect = 2e-05 Identities = 31/102 (30%), Positives = 48/102 (47%), Gaps = 3/102 (2%) Frame = +1 Query: 139 LDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPSF 318 LD E S + G+ H+HS G H ++K SN+++ ++ D GL G SF Sbjct: 123 LDHERMSYLLYQMLCGIKHLHSAG--IIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF 180 Query: 319 SPTR---VSGYRAPEVTDIRRVSQKADVYSFGVLLLELLTGK 435 T YRAPEV + D++S G ++ E++ K Sbjct: 181 MMTPYVVTRYYRAPEVILGMGYKENVDLWSVGCIMGEMVCHK 222
>YES_AVISY (P00527) Tyrosine-protein kinase transforming protein YES (EC| 2.7.10.2) (Fragment) Length = 528 Score = 47.0 bits (110), Expect = 2e-05 Identities = 32/105 (30%), Positives = 56/105 (53%), Gaps = 6/105 (5%) Frame = +1 Query: 163 IALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPSFSPTRVSG- 339 +A A G+A+I H +++++N+L+ + +++D GL L+ + R Sbjct: 366 MAAQIADGMAYIERMNYI--HRDLRAANILVGDNLVCKIADFGLARLIEDNEYTARQGAK 423 Query: 340 ----YRAPEVTDIRRVSQKADVYSFGVLLLELLT-GKAPTHAVVN 459 + APE R + K+DV+SFG+LL EL+T G+ P +VN Sbjct: 424 FPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMVN 468
>TAOK2_XENLA (Q6GPK9) Serine/threonine-protein kinase TAO2 (EC 2.7.11.1)| (Thousand and one amino acid protein 2) Length = 1025 Score = 47.0 bits (110), Expect = 2e-05 Identities = 31/105 (29%), Positives = 53/105 (50%), Gaps = 3/105 (2%) Frame = +1 Query: 136 PLDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPS 315 PL +AI +G+A++H+ H ++K+ N+LLT+ ++ D G +++ P+ Sbjct: 122 PLQEMEIAAITHGALQGLAYLHNHNMI--HRDVKAGNILLTEPGLVKLGDFGSASIMAPA 179 Query: 316 FSPTRVSGYRAPEV---TDIRRVSQKADVYSFGVLLLELLTGKAP 441 S + APEV D + K DV+S G+ +EL K P Sbjct: 180 NSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITSIELAERKPP 224
>YES_XIPHE (P27447) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 543 Score = 47.0 bits (110), Expect = 2e-05 Identities = 27/85 (31%), Positives = 48/85 (56%), Gaps = 6/85 (7%) Frame = +1 Query: 223 HGNIKSSNVLLTKSYEARVSDHGLPTLVGPSFSPTRVSG-----YRAPEVTDIRRVSQKA 387 H +++++N+L+ + +++D GL L+ + R + APE R + K+ Sbjct: 394 HRDLRAANILVADNLVCKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS 453 Query: 388 DVYSFGVLLLELLT-GKAPTHAVVN 459 DV+SFG+LL EL+T G+ P +VN Sbjct: 454 DVWSFGILLTELVTKGRVPYPGMVN 478
>WNK2_HUMAN (Q9Y3S1) Serine/threonine-protein kinase WNK2 (EC 2.7.11.1)| (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2) Length = 2297 Score = 47.0 bits (110), Expect = 2e-05 Identities = 26/90 (28%), Positives = 49/90 (54%), Gaps = 3/90 (3%) Frame = +1 Query: 181 RGVAHIHSTGPTASHGNIKSSNVLLT-KSYEARVSDHGLPTLVGPSFSPTRVSG--YRAP 351 +G+ +H+ P H ++K N+ +T + ++ D GL TL SF+ + + + AP Sbjct: 307 KGLLFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRASFAKSVIGTPEFMAP 366 Query: 352 EVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 E+ + + DVY+FG+ +LE+ T + P Sbjct: 367 EMYE-EHYDESVDVYAFGMCMLEMATSEYP 395
>STK24_MOUSE (Q99KH8) Serine/threonine-protein kinase 24 (EC 2.7.11.1)| Length = 431 Score = 47.0 bits (110), Expect = 2e-05 Identities = 34/113 (30%), Positives = 54/113 (47%), Gaps = 11/113 (9%) Frame = +1 Query: 136 PLDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLP------ 297 PLD + I +G+ ++HS H +IK++NVLL++ E +++D G+ Sbjct: 115 PLDEIQIATILREILKGLDYLHSEKKI--HRDIKAANVLLSEHGEVKLADFGVAGQLTDT 172 Query: 298 -----TLVGPSFSPTRVSGYRAPEVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 T VG F + APEV KAD++S G+ +EL G+ P Sbjct: 173 QIKRNTFVGTPF-------WMAPEVIKQSAYDSKADIWSLGITAIELAKGEPP 218
>M3K7_HUMAN (O43318) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1) Length = 606 Score = 47.0 bits (110), Expect = 2e-05 Identities = 30/94 (31%), Positives = 52/94 (55%), Gaps = 3/94 (3%) Frame = +1 Query: 169 LATARGVAHIHSTGPTAS-HGNIKSSNVLLTKSYEA-RVSDHGLPTLVGPSFSPTRVSG- 339 L ++GVA++HS P A H ++K N+LL ++ D G + + + S Sbjct: 135 LQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGTVLKICDFGTACDIQTHMTNNKGSAA 194 Query: 340 YRAPEVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 + APEV + S+K DV+S+G++L E++T + P Sbjct: 195 WMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKP 228
>KS6A_CAEEL (Q21734) Putative ribosomal protein S6 kinase alpha (EC 2.7.11.1)| Length = 784 Score = 47.0 bits (110), Expect = 2e-05 Identities = 32/87 (36%), Positives = 44/87 (50%), Gaps = 4/87 (4%) Frame = +1 Query: 193 HIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPS----FSPTRVSGYRAPEVT 360 H+HS G + ++K N+LL +V+D GL S +S Y APEV Sbjct: 219 HLHSLGIV--YRDLKPENILLDADGHIKVTDFGLSKEAIDSEKKTYSFCGTVEYMAPEVI 276 Query: 361 DIRRVSQKADVYSFGVLLLELLTGKAP 441 + R S AD +S GVL+ E+LTG P Sbjct: 277 NRRGHSMAADFWSLGVLMFEMLTGHLP 303 Score = 34.3 bits (77), Expect = 0.16 Identities = 28/103 (27%), Positives = 45/103 (43%), Gaps = 8/103 (7%) Frame = +1 Query: 157 SAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKS----YEARVSDHGLPTLV----GP 312 +AI V ++HS +H ++ ++N+L R+ D G G Sbjct: 550 AAIMANLLNAVQYLHSQ--QVAHRDLTAANILFALKDGDPSSLRIVDFGFAKQSRAENGM 607 Query: 313 SFSPTRVSGYRAPEVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 +P + + APEV + + DV+S GVLL +LTG P Sbjct: 608 LMTPCYTAQFVAPEVLRKQGYDRSCDVWSLGVLLHTMLTGCTP 650
>TGFR2_HUMAN (P37173) TGF-beta receptor type-2 precursor (EC 2.7.11.30)| (TGF-beta receptor type II) (TGFR-2) (TGF-beta type II receptor) Length = 567 Score = 47.0 bits (110), Expect = 2e-05 Identities = 37/127 (29%), Positives = 56/127 (44%), Gaps = 23/127 (18%) Frame = +1 Query: 112 GNRSSGLTP--LDWEARSAIALATARGVAHIHSTGPTAS-------HGNIKSSNVLLTKS 264 GN LT + WE + + ARG+AH+HS H ++KSSN+L+ Sbjct: 331 GNLQEYLTRHVISWEDLRKLGSSLARGIAHLHSDHTPCGRPKMPIVHRDLKSSNILVKND 390 Query: 265 YEARVSDHGLPTLVGPSFSPTRVSG--------YRAPEVTDIRRVSQKA------DVYSF 402 + D GL + P+ S ++ Y APEV + R + A DVYS Sbjct: 391 LTCCLCDFGLSLRLDPTLSVDDLANSGQVGTARYMAPEVLESRMNLENAESFKQTDVYSM 450 Query: 403 GVLLLEL 423 ++L E+ Sbjct: 451 ALVLWEM 457
>KS6A6_HUMAN (Q9UK32) Ribosomal protein S6 kinase alpha-6 (EC 2.7.11.1)| (S6K-alpha 6) (90 kDa ribosomal protein S6 kinase 6) (p90-RSK 6) (Ribosomal S6 kinase 4) (RSK-4) (pp90RSK4) Length = 745 Score = 47.0 bits (110), Expect = 2e-05 Identities = 31/92 (33%), Positives = 48/92 (52%), Gaps = 4/92 (4%) Frame = +1 Query: 178 ARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPT----LVGPSFSPTRVSGYR 345 A + H+H G + ++K N+LL + +++D GL ++S Y Sbjct: 183 ALALDHLHQLGIV--YRDLKPENILLDEIGHIKLTDFGLSKESVDQEKKAYSFCGTVEYM 240 Query: 346 APEVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 APEV + R SQ AD +S+GVL+ E+LTG P Sbjct: 241 APEVVNRRGHSQSADWWSYGVLMFEMLTGTLP 272 Score = 35.0 bits (79), Expect = 0.093 Identities = 29/103 (28%), Positives = 47/103 (45%), Gaps = 8/103 (7%) Frame = +1 Query: 157 SAIALATARGVAHIHSTGPTASHGNIKSSNVL-LTKSYEA---RVSDHGLPTLV----GP 312 S I ++ V ++H G H ++K SN+L + +S A R+ D G + G Sbjct: 521 SDILYVISKTVDYLHCQGVV--HRDLKPSNILYMDESASADSIRICDFGFAKQLRGENGL 578 Query: 313 SFSPTRVSGYRAPEVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 +P + + APEV + D++S GVL +L G P Sbjct: 579 LLTPCYTANFVAPEVLMQQGYDAACDIWSLGVLFYTMLAGYTP 621
>MK08_MOUSE (Q91Y86) Mitogen-activated protein kinase 8 (EC 2.7.11.24)| (Stress-activated protein kinase JNK1) (c-Jun N-terminal kinase 1) Length = 384 Score = 47.0 bits (110), Expect = 2e-05 Identities = 31/102 (30%), Positives = 48/102 (47%), Gaps = 3/102 (2%) Frame = +1 Query: 139 LDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPSF 318 LD E S + G+ H+HS G H ++K SN+++ ++ D GL G SF Sbjct: 123 LDHERMSYLLYQMLCGIKHLHSAG--IIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF 180 Query: 319 SPTR---VSGYRAPEVTDIRRVSQKADVYSFGVLLLELLTGK 435 T YRAPEV + D++S G ++ E++ K Sbjct: 181 MMTPYVVTRYYRAPEVILGMGYKENVDLWSVGCIMGEMVCHK 222
>GUC2D_CANFA (O19179) Retinal guanylyl cyclase 1 precursor (EC 4.6.1.2)| (Guanylate cyclase 2D, retinal) (RETGC-1) (Rod outer segment membrane guanylate cyclase) (ROS-GC) (Guanylate cyclase E) (GC-E) Length = 1109 Score = 47.0 bits (110), Expect = 2e-05 Identities = 31/110 (28%), Positives = 55/110 (50%), Gaps = 9/110 (8%) Frame = +1 Query: 139 LDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPS- 315 LDW +S++ L +G+ ++H G +HG +KS N ++ + +V+DHG L+ Sbjct: 642 LDWMFKSSLLLDLIKGMRYLHHRG--VAHGRLKSRNCVVDGRFVLKVTDHGHARLMEAQR 699 Query: 316 --FSPTRVSG--YRAPEVTD----IRRVSQKADVYSFGVLLLELLTGKAP 441 P + APE+ RR + DV+S G+++ E++ AP Sbjct: 700 VLLEPPSAEDQLWTAPELLRDPALERRGTLPGDVFSLGIIMQEVVCRSAP 749
>CLA4_YEAST (P48562) Serine/threonine-protein kinase CLA4 (EC 2.7.11.1)| Length = 842 Score = 47.0 bits (110), Expect = 2e-05 Identities = 33/114 (28%), Positives = 52/114 (45%), Gaps = 11/114 (9%) Frame = +1 Query: 133 TPLDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGL------ 294 +PL + I T +G+ +H H +IKS NVLL +++D G Sbjct: 663 SPLTEPQIAYIVRETCQGLKFLHDKH--IIHRDIKSDNVLLDTRARVKITDFGFCARLTD 720 Query: 295 -----PTLVGPSFSPTRVSGYRAPEVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 T+VG + + APEV R +K DV+S G++ +E+L G+ P Sbjct: 721 KRSKRATMVGTPY-------WMAPEVVKQREYDEKIDVWSLGIMTIEMLEGEPP 767
>YES_CHICK (P09324) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 540 Score = 47.0 bits (110), Expect = 2e-05 Identities = 32/105 (30%), Positives = 56/105 (53%), Gaps = 6/105 (5%) Frame = +1 Query: 163 IALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPSFSPTRVSG- 339 +A A G+A+I H +++++N+L+ + +++D GL L+ + R Sbjct: 373 MAAQIADGMAYIERMNYI--HRDLRAANILVGDNLVCKIADFGLARLIEDNEYTARQGAK 430 Query: 340 ----YRAPEVTDIRRVSQKADVYSFGVLLLELLT-GKAPTHAVVN 459 + APE R + K+DV+SFG+LL EL+T G+ P +VN Sbjct: 431 FPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMVN 475
>SRC_MOUSE (P05480) Neuronal proto-oncogene tyrosine-protein kinase Src (EC| 2.7.10.2) (p60-Src) (c-Src) (pp60c-src) Length = 540 Score = 47.0 bits (110), Expect = 2e-05 Identities = 31/100 (31%), Positives = 54/100 (54%), Gaps = 6/100 (6%) Frame = +1 Query: 178 ARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPSFSPTRVSG-----Y 342 A G+A++ H +++++N+L+ ++ +V+D GL L+ + R + Sbjct: 378 ASGMAYVERMNYV--HRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKW 435 Query: 343 RAPEVTDIRRVSQKADVYSFGVLLLELLT-GKAPTHAVVN 459 APE R + K+DV+SFG+LL EL T G+ P +VN Sbjct: 436 TAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVN 475
>BLK_HUMAN (P51451) Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte| kinase) (p55-BLK) Length = 504 Score = 47.0 bits (110), Expect = 2e-05 Identities = 28/99 (28%), Positives = 57/99 (57%), Gaps = 5/99 (5%) Frame = +1 Query: 178 ARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPSFSPTRVSGY----R 345 A G+A+I + H +++++N+L++++ +++D GL ++ ++ + + Sbjct: 344 AEGMAYIERMN--SIHRDLRAANILVSEALCCKIADFGLARIIDSEYTAQEGAKFPIKWT 401 Query: 346 APEVTDIRRVSQKADVYSFGVLLLELLT-GKAPTHAVVN 459 APE + KADV+SFGVLL+E++T G+ P + N Sbjct: 402 APEAIHFGVFTIKADVWSFGVLLMEVVTYGRVPYPGMSN 440
>RIPK5_XENTR (Q67E00) Receptor-interacting serine/threonine-protein kinase 5 (EC| 2.7.11.1) (Dusty protein kinase) (Dusty PK) Length = 918 Score = 46.6 bits (109), Expect = 3e-05 Identities = 33/103 (32%), Positives = 51/103 (49%), Gaps = 3/103 (2%) Frame = +1 Query: 133 TPLDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGL---PTL 303 T L E R IAL G+ +H+ G H +IK NVLL K + A+++D G + Sbjct: 738 TGLSLETRLQIALDVVEGIRFLHNQGLV--HRDIKLKNVLLDKKHRAKITDLGFCKPEAM 795 Query: 304 VGPSFSPTRVSGYRAPEVTDIRRVSQKADVYSFGVLLLELLTG 432 + S T + + APE+ + DVY+FG+L + +G Sbjct: 796 MSGSIVGTPI--HMAPELFS-GKYDNSVDVYAFGILFWYICSG 835
>PKNB_MYCLE (P54744) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 622 Score = 46.6 bits (109), Expect = 3e-05 Identities = 24/79 (30%), Positives = 43/79 (54%), Gaps = 6/79 (7%) Frame = +1 Query: 223 HGNIKSSNVLLTKSYEARVSDHGLPTLVGPSFSPTRVSG------YRAPEVTDIRRVSQK 384 H ++K +N++++ + +V D G+ + S S T+ + Y +PE V + Sbjct: 136 HRDVKPANIMISATNAVKVMDFGIARAIADSTSVTQTAAVIGTAQYLSPEQARGDSVDAR 195 Query: 385 ADVYSFGVLLLELLTGKAP 441 +DVYS G +L E+LTG+ P Sbjct: 196 SDVYSLGCVLYEILTGEPP 214
>KPCT_HUMAN (Q04759) Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta)| Length = 706 Score = 46.6 bits (109), Expect = 3e-05 Identities = 29/92 (31%), Positives = 51/92 (55%), Gaps = 4/92 (4%) Frame = +1 Query: 184 GVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGL--PTLVGPSFSPT--RVSGYRAP 351 G+ +HS G + ++K N+LL K +++D G+ ++G + + T Y AP Sbjct: 491 GLQFLHSKGIV--YRDLKLDNILLDKDGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAP 548 Query: 352 EVTDIRRVSQKADVYSFGVLLLELLTGKAPTH 447 E+ ++ + D +SFGVLL E+L G++P H Sbjct: 549 EILLGQKYNHSVDWWSFGVLLYEMLIGQSPFH 580
>SRC_RAT (Q9WUD9) Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2)| (p60-Src) (c-Src) (pp60c-src) Length = 535 Score = 46.6 bits (109), Expect = 3e-05 Identities = 28/85 (32%), Positives = 48/85 (56%), Gaps = 6/85 (7%) Frame = +1 Query: 223 HGNIKSSNVLLTKSYEARVSDHGLPTLVGPSFSPTRVSG-----YRAPEVTDIRRVSQKA 387 H +++++N+L+ ++ +V+D GL L+ + R + APE R + K+ Sbjct: 386 HRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS 445 Query: 388 DVYSFGVLLLELLT-GKAPTHAVVN 459 DV+SFG+LL EL T G+ P +VN Sbjct: 446 DVWSFGILLTELTTKGRVPYPGMVN 470
>TAOK2_MOUSE (Q6ZQ29) Serine/threonine-protein kinase TAO2 (EC 2.7.11.1)| (Thousand and one amino acid protein 2) Length = 1055 Score = 46.6 bits (109), Expect = 3e-05 Identities = 30/105 (28%), Positives = 53/105 (50%), Gaps = 3/105 (2%) Frame = +1 Query: 136 PLDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPS 315 PL +A+ +G+A++HS H ++K+ N+LL++ ++ D G +++ P+ Sbjct: 122 PLQEVEIAAVTHGALQGLAYLHSHNMI--HRDVKAGNILLSEPGLVKLGDFGSASIMAPA 179 Query: 316 FSPTRVSGYRAPEV---TDIRRVSQKADVYSFGVLLLELLTGKAP 441 S + APEV D + K DV+S G+ +EL K P Sbjct: 180 NSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPP 224
>RIPK5_CHICK (Q6XUX0) Receptor-interacting serine/threonine-protein kinase 5 (EC| 2.7.11.1) (Dusty protein kinase) (Dusty PK) Length = 930 Score = 46.6 bits (109), Expect = 3e-05 Identities = 33/101 (32%), Positives = 51/101 (50%), Gaps = 3/101 (2%) Frame = +1 Query: 139 LDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGL---PTLVG 309 L+ E R IAL G+ ++HS G H +IK NVLL K A+++D G ++ Sbjct: 750 LELETRLQIALDVVEGIRYLHSQG--LVHRDIKLKNVLLDKKNRAKITDLGFCKPEAMMS 807 Query: 310 PSFSPTRVSGYRAPEVTDIRRVSQKADVYSFGVLLLELLTG 432 S T + + APE+ + DVY+FG+L + +G Sbjct: 808 GSIVGTPI--HMAPELF-TGKYDNSVDVYAFGILFWYICSG 845
>NRKB_TRYBB (Q03428) Putative serine/threonine-protein kinase B (EC 2.7.11.1)| Length = 431 Score = 46.6 bits (109), Expect = 3e-05 Identities = 32/84 (38%), Positives = 47/84 (55%), Gaps = 8/84 (9%) Frame = +1 Query: 223 HGNIKSSNVLLTKSYEARVSDHG--------LPTLVGPSFSPTRVSGYRAPEVTDIRRVS 378 H +IKS+NVLLT + ++ D G + +V +F T Y APE+ + R + Sbjct: 145 HRDIKSANVLLTSTGLVKLGDFGFSHQYEDTVSGVVASTFCGTPY--YLAPELWNNLRYN 202 Query: 379 QKADVYSFGVLLLELLTGKAPTHA 450 +KADV+S GVLL E++ K P A Sbjct: 203 KKADVWSLGVLLYEIMGMKKPFSA 226
>NEK3_HUMAN (P51956) Serine/threonine-protein kinase Nek3 (EC 2.7.11.1)| (NimA-related protein kinase 3) (HSPK 36) Length = 506 Score = 46.6 bits (109), Expect = 3e-05 Identities = 32/93 (34%), Positives = 49/93 (52%), Gaps = 4/93 (4%) Frame = +1 Query: 184 GVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGP--SFSPTRVSG--YRAP 351 GV HIH H +IKS N+ LT++ + ++ D G L+ +F+ T V Y P Sbjct: 114 GVNHIHKK--RVLHRDIKSKNIFLTQNGKVKLGDFGSARLLSNPMAFACTYVGTPYYVPP 171 Query: 352 EVTDIRRVSQKADVYSFGVLLLELLTGKAPTHA 450 E+ + + K+D++S G +L EL T K P A Sbjct: 172 EIWENLPYNNKSDIWSLGCILYELCTLKHPFQA 204
>MP2K5_RAT (Q62862) Dual specificity mitogen-activated protein kinase kinase 5| (EC 2.7.12.2) (MAP kinase kinase 5) (MAPKK 5) (MAPK/ERK kinase 5) Length = 448 Score = 46.6 bits (109), Expect = 3e-05 Identities = 29/95 (30%), Positives = 51/95 (53%), Gaps = 2/95 (2%) Frame = +1 Query: 163 IALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPSFSPTRV--S 336 IA+A +G+ ++ S H ++K SN+L+ S + ++ D G+ T + S + T V + Sbjct: 263 IAVAVVKGLTYLWSL--KILHRDVKPSNMLVNTSGQVKLCDFGVSTQLVNSIAKTYVGTN 320 Query: 337 GYRAPEVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 Y APE + +DV+S G+ +EL G+ P Sbjct: 321 AYMAPERISGEQYGIHSDVWSLGISFMELALGRFP 355
>STK6L_XENLA (Q91819) Serine/threonine-protein kinase Eg2-like (EC 2.7.11.1)| (p46XlEg22) Length = 408 Score = 46.6 bits (109), Expect = 3e-05 Identities = 34/102 (33%), Positives = 53/102 (51%), Gaps = 4/102 (3%) Frame = +1 Query: 148 EARSAIALAT-ARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPSFSP 324 + RSA+ + A + + HS H +IK N+LL + E +++D G ++ PS Sbjct: 237 DQRSALYIKQLAEALLYCHSK--KVIHRDIKPENLLLGSNGELKIADFGW-SVHAPSSRR 293 Query: 325 TRVSG---YRAPEVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 T + G Y PE+ + R +K D++S GVL E L GK P Sbjct: 294 TTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPP 335
>TAOK2_RAT (Q9JLS3) Serine/threonine-protein kinase TAO2 (EC 2.7.11.1)| (Thousand and one amino acid protein 2) Length = 1235 Score = 46.6 bits (109), Expect = 3e-05 Identities = 30/105 (28%), Positives = 53/105 (50%), Gaps = 3/105 (2%) Frame = +1 Query: 136 PLDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPS 315 PL +A+ +G+A++HS H ++K+ N+LL++ ++ D G +++ P+ Sbjct: 122 PLQEVEIAAVTHGALQGLAYLHSHNMI--HRDVKAGNILLSEPGLVKLGDFGSASIMAPA 179 Query: 316 FSPTRVSGYRAPEV---TDIRRVSQKADVYSFGVLLLELLTGKAP 441 S + APEV D + K DV+S G+ +EL K P Sbjct: 180 NSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPP 224
>TAOK2_HUMAN (Q9UL54) Serine/threonine-protein kinase TAO2 (EC 2.7.11.1)| (Thousand and one amino acid protein 2) (Prostate-derived STE20-like kinase 1) (PSK-1) (Kinase from chicken homolog C) (hKFC-C) Length = 1235 Score = 46.6 bits (109), Expect = 3e-05 Identities = 30/105 (28%), Positives = 53/105 (50%), Gaps = 3/105 (2%) Frame = +1 Query: 136 PLDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPS 315 PL +A+ +G+A++HS H ++K+ N+LL++ ++ D G +++ P+ Sbjct: 122 PLQEVEIAAVTHGALQGLAYLHSHNMI--HRDVKAGNILLSEPGLVKLGDFGSASIMAPA 179 Query: 316 FSPTRVSGYRAPEV---TDIRRVSQKADVYSFGVLLLELLTGKAP 441 S + APEV D + K DV+S G+ +EL K P Sbjct: 180 NSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPP 224
>MOS_MOUSE (P00536) Proto-oncogene serine/threonine-protein kinase mos (EC| 2.7.11.1) (c-mos) (Oocyte maturation factor mos) Length = 390 Score = 46.2 bits (108), Expect = 4e-05 Identities = 29/99 (29%), Positives = 52/99 (52%), Gaps = 7/99 (7%) Frame = +1 Query: 166 ALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHG----LPTLVGPSFSPTRV 333 +L G+ +HS + H ++K +N+L+++ ++SD G L L SP + Sbjct: 226 SLDVVNGLLFLHSQ--SILHLDLKPANILISEQDVCKISDFGCSQKLQVLRCRQASPHHI 283 Query: 334 SG---YRAPEVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 G ++APE+ + KAD+YSFG+ L ++ T + P Sbjct: 284 GGTYTHQAPEILKGEIATPKADIYSFGITLWQMTTREVP 322
>FGR_HUMAN (P09769) Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2)| (P55-FGR) (C-FGR) Length = 529 Score = 46.2 bits (108), Expect = 4e-05 Identities = 30/99 (30%), Positives = 56/99 (56%), Gaps = 6/99 (6%) Frame = +1 Query: 163 IALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLV-GPSFSPTRVSG 339 +A A G+A++ H +++++N+L+ + +++D GL L+ ++P + S Sbjct: 362 MAAQVAEGMAYMERMNYI--HRDLRAANILVGERLACKIADFGLARLIKDDEYNPCQGSK 419 Query: 340 Y----RAPEVTDIRRVSQKADVYSFGVLLLELLT-GKAP 441 + APE R + K+DV+SFG+LL EL+T G+ P Sbjct: 420 FPIKWTAPEAALFGRFTIKSDVWSFGILLTELITKGRIP 458
>GUC2E_RAT (P51840) Guanylyl cyclase GC-E precursor (EC 4.6.1.2) (Guanylate| cyclase 2E) Length = 1108 Score = 46.2 bits (108), Expect = 4e-05 Identities = 31/110 (28%), Positives = 54/110 (49%), Gaps = 9/110 (8%) Frame = +1 Query: 139 LDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTL----- 303 LDW +S++ L +G+ ++H G +HG +KS N ++ + +V+DHG L Sbjct: 641 LDWMFKSSLLLDLIKGMRYLHHRG--VAHGRLKSRNCVVDGRFVLKVTDHGHGRLLEAQR 698 Query: 304 VGPSFSPTRVSGYRAPEVTD----IRRVSQKADVYSFGVLLLELLTGKAP 441 V P + APE+ RR + DV+S G+++ E++ P Sbjct: 699 VLPEPPSAEDQLWTAPELLRDPALERRGTLAGDVFSLGIIMQEVVCRSTP 748
>TGFR2_RAT (P38438) TGF-beta receptor type-2 precursor (EC 2.7.11.30)| (TGF-beta receptor type II) (TGFR-2) (TGF-beta type II receptor) Length = 567 Score = 46.2 bits (108), Expect = 4e-05 Identities = 36/127 (28%), Positives = 56/127 (44%), Gaps = 23/127 (18%) Frame = +1 Query: 112 GNRSSGLTP--LDWEARSAIALATARGVAHIHSTGPTAS-------HGNIKSSNVLLTKS 264 GN LT + WE + + ARG+AH+HS H ++KSSN+L+ Sbjct: 331 GNLQEYLTRHVISWEDLRKLGSSLARGIAHLHSDHTPCGRPKMPIVHRDLKSSNILVKND 390 Query: 265 YEARVSDHGLPTLVGPSFSPTRVSG--------YRAPEVTDIR------RVSQKADVYSF 402 + D GL + P+ S ++ Y APEV + R ++ DVYS Sbjct: 391 LTCCLCDFGLSLRLDPTLSVDDLANSGQVGTARYMAPEVLESRMNLENMESFKQTDVYSM 450 Query: 403 GVLLLEL 423 ++L E+ Sbjct: 451 ALVLWEM 457
>STK6_MOUSE (P97477) Serine/threonine-protein kinase 6 (EC 2.7.11.1)| (Aurora-family kinase 1) (Aurora/IPL1-related kinase 1) (Ipl1- and aurora-related kinase 1) (Aurora-A) (Serine/threonine-protein kinase Ayk1) Length = 395 Score = 46.2 bits (108), Expect = 4e-05 Identities = 33/110 (30%), Positives = 53/110 (48%), Gaps = 3/110 (2%) Frame = +1 Query: 130 LTPLDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVG 309 L+ D + + A +++ HS H +IK N+LL + E +++D G ++ Sbjct: 216 LSKFDEQRTATYITELANALSYCHSK--RVIHRDIKPENLLLGSNGELKIADFGW-SVHA 272 Query: 310 PSFSPTRVSG---YRAPEVTDIRRVSQKADVYSFGVLLLELLTGKAPTHA 450 PS T + G Y PE+ + R +K D++S GVL E L G P A Sbjct: 273 PSSRRTTMCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGMPPFEA 322
>PKSC_STRCO (Q9S2C0) Serine/threonine protein kinase pksC (EC 2.7.11.1)| Length = 556 Score = 46.2 bits (108), Expect = 4e-05 Identities = 32/118 (27%), Positives = 53/118 (44%), Gaps = 7/118 (5%) Frame = +1 Query: 118 RSSGLTPLDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLP 297 R G P D + + A ++H H +IK NV++TK +V D G+ Sbjct: 118 RQQGAMPADKALKITADVLAALEISHEMGL----VHRDIKPGNVMMTKRGVVKVMDFGIA 173 Query: 298 TLVGPSFSPTRVSG-------YRAPEVTDIRRVSQKADVYSFGVLLLELLTGKAPTHA 450 + + +G Y +PE R V ++D+YS G++L +L+TG+ P A Sbjct: 174 RAMQSGVTSMTQTGMVVGTPQYLSPEQALGRGVDARSDLYSVGIMLFQLVTGRLPFDA 231
>MK10_RAT (P49187) Mitogen-activated protein kinase 10 (EC 2.7.11.24)| (Stress-activated protein kinase JNK3) (c-Jun N-terminal kinase 3) (SAPK-beta) (p54-beta) Length = 464 Score = 46.2 bits (108), Expect = 4e-05 Identities = 30/102 (29%), Positives = 47/102 (46%), Gaps = 3/102 (2%) Frame = +1 Query: 139 LDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPSF 318 LD E S + + H+HS G H ++K SN+++ ++ D GL G SF Sbjct: 161 LDHERMSYLLYQMLSAIKHLHSAG--IIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF 218 Query: 319 SPTR---VSGYRAPEVTDIRRVSQKADVYSFGVLLLELLTGK 435 T YRAPEV + D++S G ++ E++ K Sbjct: 219 MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMVRHK 260
>FYN_XIPHE (P27446) Proto-oncogene tyrosine-protein kinase FYN (EC 2.7.10.2)| (P59-FYN) Length = 536 Score = 46.2 bits (108), Expect = 4e-05 Identities = 31/99 (31%), Positives = 53/99 (53%), Gaps = 6/99 (6%) Frame = +1 Query: 163 IALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPSFSPTRVSG- 339 +A A G+A+I H +++S+N+L+ + +++D GL L+ + R Sbjct: 369 MAAQVAAGMAYIERMNYI--HRDLRSANILVGDNLVCKIADFGLARLIEDNEYTARQGAK 426 Query: 340 ----YRAPEVTDIRRVSQKADVYSFGVLLLELLT-GKAP 441 + APE R + K+DV+SFG+LL EL+T G+ P Sbjct: 427 FPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVP 465
>GUC2D_HUMAN (Q02846) Retinal guanylyl cyclase 1 precursor (EC 4.6.1.2)| (Guanylate cyclase 2D, retinal) (RETGC-1) (Rod outer segment membrane guanylate cyclase) (ROS-GC) Length = 1103 Score = 46.2 bits (108), Expect = 4e-05 Identities = 30/110 (27%), Positives = 55/110 (50%), Gaps = 9/110 (8%) Frame = +1 Query: 139 LDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPSF 318 LDW +S++ L +G+ ++H G +HG +KS N ++ + +++DHG L+ Sbjct: 638 LDWMFKSSLLLDLIKGIRYLHHRG--VAHGRLKSRNCIVDGRFVLKITDHGHGRLLEAQK 695 Query: 319 ---SPTRVSG--YRAPEVTD----IRRVSQKADVYSFGVLLLELLTGKAP 441 P R + APE+ RR + DV+S +++ E++ AP Sbjct: 696 VLPEPPRAEDQLWTAPELLRDPALERRGTLAGDVFSLAIIMQEVVCRSAP 745
>TGFR2_MOUSE (Q62312) TGF-beta receptor type-2 precursor (EC 2.7.11.30)| (TGF-beta receptor type II) (TGFR-2) (TGF-beta type II receptor) Length = 592 Score = 46.2 bits (108), Expect = 4e-05 Identities = 36/127 (28%), Positives = 56/127 (44%), Gaps = 23/127 (18%) Frame = +1 Query: 112 GNRSSGLTP--LDWEARSAIALATARGVAHIHSTGPTAS-------HGNIKSSNVLLTKS 264 GN LT + WE + + ARG+AH+HS H ++KSSN+L+ Sbjct: 356 GNLQEYLTRHVISWEDLRKLGSSLARGIAHLHSDHTPCGRPKMPIVHRDLKSSNILVKND 415 Query: 265 YEARVSDHGLPTLVGPSFSPTRVSG--------YRAPEVTDIR------RVSQKADVYSF 402 + D GL + P+ S ++ Y APEV + R ++ DVYS Sbjct: 416 LTCCLCDFGLSLRLDPTLSVDDLANSGQVGTARYMAPEVLESRMNLENVESFKQTDVYSM 475 Query: 403 GVLLLEL 423 ++L E+ Sbjct: 476 ALVLWEM 482
>MOS_CHICK (P10741) Serine/threonine-protein kinase mos (EC 2.7.11.1) (Oocyte| maturation factor mos) Length = 349 Score = 46.2 bits (108), Expect = 4e-05 Identities = 31/111 (27%), Positives = 55/111 (49%), Gaps = 15/111 (13%) Frame = +1 Query: 154 RSAIALATA--------RGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVG 309 R A+++A A G+A +HS G H ++K +N+L+T+ ++ D G + Sbjct: 174 RKALSMAEAVCYSCDIVTGLAFLHSQGIV--HLDLKPANILITEHGACKIGDFGCSQRLE 231 Query: 310 PSFSPTR-------VSGYRAPEVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 S + +RAPE+ RV+ KAD+YSF + L +++ + P Sbjct: 232 EGLSQSHHVCQQGGTYTHRAPELLKGERVTAKADIYSFAITLWQIVMREQP 282
>MK08_RAT (P49185) Mitogen-activated protein kinase 8 (EC 2.7.11.24)| (Stress-activated protein kinase JNK1) (c-Jun N-terminal kinase 1) (SAPK gamma) (p54 gamma) Length = 411 Score = 46.2 bits (108), Expect = 4e-05 Identities = 30/99 (30%), Positives = 47/99 (47%), Gaps = 3/99 (3%) Frame = +1 Query: 139 LDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPSF 318 LD E S + G+ H+HS G H ++K SN+++ ++ D GL G SF Sbjct: 123 LDHERMSYLLYQMLCGIKHLHSAG--IIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF 180 Query: 319 SPTR---VSGYRAPEVTDIRRVSQKADVYSFGVLLLELL 426 T YRAPEV + D++S G ++ E++ Sbjct: 181 MMTPYVVTRYYRAPEVILGMGYKENVDLWSVGCIMGEMV 219
>KPK1_ARATH (P42818) Serine/threonine-protein kinase AtPK1/AtPK6 (EC 2.7.11.1)| Length = 465 Score = 46.2 bits (108), Expect = 4e-05 Identities = 28/88 (31%), Positives = 44/88 (50%), Gaps = 3/88 (3%) Frame = +1 Query: 187 VAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPSFSPTRVSG---YRAPEV 357 V+H+H G H ++K N+L+ ++D GL + + G Y APE+ Sbjct: 245 VSHLHEKG--IMHRDLKPENILMDTDGHVMLTDFGLAKEFEENTRSNSMCGTTEYMAPEI 302 Query: 358 TDIRRVSQKADVYSFGVLLLELLTGKAP 441 + + AD +S G+LL E+LTGK P Sbjct: 303 VRGKGHDKAADWWSVGILLYEMLTGKPP 330
>MLTK_HUMAN (Q9NYL2) Mitogen-activated protein kinase kinase kinase MLT (EC| 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper-and sterile alpha motif-containing kinase) (Sterile alpha motif- and leucine zipper-containing kinase Length = 800 Score = 46.2 bits (108), Expect = 4e-05 Identities = 29/95 (30%), Positives = 47/95 (49%), Gaps = 3/95 (3%) Frame = +1 Query: 166 ALATARGVAHIHSTGPT-ASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPSFSPTRVSGY 342 A A+G+ ++H P H ++KS NV++ ++ D G + + V + Sbjct: 111 ATDVAKGMHYLHMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASRFHNHTTHMSLVGTF 170 Query: 343 --RAPEVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 APEV VS+ D YS+GV+L E+LT + P Sbjct: 171 PWMAPEVIQSLPVSETCDTYSYGVVLWEMLTREVP 205
>PAK4_HUMAN (O96013) Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1)| (p21-activated kinase 4) (PAK-4) Length = 591 Score = 46.2 bits (108), Expect = 4e-05 Identities = 30/108 (27%), Positives = 56/108 (51%), Gaps = 5/108 (4%) Frame = +1 Query: 133 TPLDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGP 312 T ++ E +A+ LA + ++ +H+ G H +IKS ++LLT ++SD G V Sbjct: 410 TRMNEEQIAAVCLAVLQALSVLHAQG--VIHRDIKSDSILLTHDGRVKLSDFGFCAQVSK 467 Query: 313 SFSPTRVS-----GYRAPEVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 P R S + APE+ + D++S G++++E++ G+ P Sbjct: 468 EV-PRRKSLVGTPYWMAPELISRLPYGPEVDIWSLGIMVIEMVDGEPP 514
>CLA4_ASHGO (Q9HFW2) Serine/threonine-protein kinase CLA4 (EC 2.7.11.1)| Length = 793 Score = 46.2 bits (108), Expect = 4e-05 Identities = 31/104 (29%), Positives = 48/104 (46%), Gaps = 11/104 (10%) Frame = +1 Query: 163 IALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGL-----------PTLVG 309 I T +G+ +H H +IKS NVLL +++D G T+VG Sbjct: 624 IVRETCQGLKFLHDKH--IIHRDIKSDNVLLDTHGRVKITDFGFCAKLTDKRSKRATMVG 681 Query: 310 PSFSPTRVSGYRAPEVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 + + APEV R +K DV+S G++ +E+L G+ P Sbjct: 682 TPY-------WMAPEVVKQREYDEKVDVWSLGIMTIEMLEGEPP 718
>AMHR2_HUMAN (Q16671) Anti-Muellerian hormone type-2 receptor precursor (EC| 2.7.11.30) (Anti-Muellerian hormone type II receptor) (AMH type II receptor) (MIS type II receptor) (MISRII) (MRII) Length = 573 Score = 45.8 bits (107), Expect = 5e-05 Identities = 35/126 (27%), Positives = 59/126 (46%), Gaps = 30/126 (23%) Frame = +1 Query: 142 DWEARSAIALATARGVAHIHSTG-------PTASHGNIKSSNVLLTKSYEARVSDHGLPT 300 DW + +AL+ A+G+A +H P +H ++ S NVL+ + + D GL Sbjct: 297 DWGSSLRMALSLAQGLAFLHEERWQNGQYKPGIAHRDLSSQNVLIREDGSCAIGDLGLAL 356 Query: 301 LVG-----PSFSPTRVSG-----------YRAPEVTDIRRVSQ-------KADVYSFGVL 411 ++ P+++PT+ G Y APE+ D Q +AD+YS +L Sbjct: 357 VLPGLTQPPAWTPTQPQGPAAIMEAGTQRYMAPELLDKTLDLQDWGMALRRADIYSLALL 416 Query: 412 LLELLT 429 L E+L+ Sbjct: 417 LWEILS 422
>FYN_MOUSE (P39688) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 533 Score = 45.8 bits (107), Expect = 5e-05 Identities = 31/99 (31%), Positives = 52/99 (52%), Gaps = 6/99 (6%) Frame = +1 Query: 163 IALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPSFSPTRVSG- 339 +A A G+A+I H +++S+N+L+ +++D GL L+ + R Sbjct: 366 MAAQVAAGMAYIERMNYI--HRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAK 423 Query: 340 ----YRAPEVTDIRRVSQKADVYSFGVLLLELLT-GKAP 441 + APE R + K+DV+SFG+LL EL+T G+ P Sbjct: 424 FPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVP 462
>FYN_CHICK (Q05876) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 533 Score = 45.8 bits (107), Expect = 5e-05 Identities = 31/99 (31%), Positives = 52/99 (52%), Gaps = 6/99 (6%) Frame = +1 Query: 163 IALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPSFSPTRVSG- 339 +A A G+A+I H +++S+N+L+ +++D GL L+ + R Sbjct: 366 MAAQVAAGMAYIERMNYI--HRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAK 423 Query: 340 ----YRAPEVTDIRRVSQKADVYSFGVLLLELLT-GKAP 441 + APE R + K+DV+SFG+LL EL+T G+ P Sbjct: 424 FPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVP 462
>ZAP70_HUMAN (P43403) Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa| zeta-associated protein) (Syk-related tyrosine kinase) Length = 619 Score = 45.8 bits (107), Expect = 5e-05 Identities = 28/81 (34%), Positives = 47/81 (58%), Gaps = 8/81 (9%) Frame = +1 Query: 223 HGNIKSSNVLLTKSYEARVSDHGLPTLVGP--SFSPTRVSG-----YRAPEVTDIRRVSQ 381 H ++ + NVLL + A++SD GL +G S+ R +G + APE + R+ S Sbjct: 459 HRDLAARNVLLVNRHYAKISDFGLSKALGADDSYYTARSAGKWPLKWYAPECINFRKFSS 518 Query: 382 KADVYSFGVLLLELLT-GKAP 441 ++DV+S+GV + E L+ G+ P Sbjct: 519 RSDVWSYGVTMWEALSYGQKP 539
>FYN_HUMAN (P06241) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) (Protooncogene Syn) (SLK) Length = 536 Score = 45.8 bits (107), Expect = 5e-05 Identities = 31/99 (31%), Positives = 52/99 (52%), Gaps = 6/99 (6%) Frame = +1 Query: 163 IALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPSFSPTRVSG- 339 +A A G+A+I H +++S+N+L+ +++D GL L+ + R Sbjct: 369 MAAQVAAGMAYIERMNYI--HRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAK 426 Query: 340 ----YRAPEVTDIRRVSQKADVYSFGVLLLELLT-GKAP 441 + APE R + K+DV+SFG+LL EL+T G+ P Sbjct: 427 FPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVP 465
>MK14_XENLA (P47812) Mitogen-activated protein kinase 14 (EC 2.7.11.24)| (Mitogen-activated Mitogen-activated protein kinase 2) (MAP kinase 2) (MPK2) Length = 361 Score = 45.8 bits (107), Expect = 5e-05 Identities = 28/87 (32%), Positives = 46/87 (52%), Gaps = 2/87 (2%) Frame = +1 Query: 181 RGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPSFSP-TRVSGYRAPEV 357 RG+ +IHS G H ++K SN+ + + E ++ D GL + YRAPE+ Sbjct: 137 RGLKYIHSAG--IIHRDLKPSNLAVNEDCELKILDFGLARHTDEEMTGYVATRWYRAPEI 194 Query: 358 T-DIRRVSQKADVYSFGVLLLELLTGK 435 + +Q D++S G ++ ELLTG+ Sbjct: 195 MLNWMHYNQTVDIWSVGCIMAELLTGR 221
>M3K7_DROME (Q9V3Q6) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (TGF-beta-activated kinase 1) (dTAK1) Length = 678 Score = 45.8 bits (107), Expect = 5e-05 Identities = 31/99 (31%), Positives = 54/99 (54%), Gaps = 5/99 (5%) Frame = +1 Query: 178 ARGVAHIHSTGPTAS-HGNIKSSNVLLT-KSYEARVSDHGLPTLVGPSFSPTRVSG---Y 342 A G+A++H+ P H ++K N+LLT K ++ D G T+ S T G + Sbjct: 122 AEGLAYLHAMTPKPLIHRDVKPLNLLLTNKGRNLKICDFG--TVADKSTMMTNNRGSAAW 179 Query: 343 RAPEVTDIRRVSQKADVYSFGVLLLELLTGKAPTHAVVN 459 APEV + + ++K D++S+ ++L E+L+ K P + N Sbjct: 180 MAPEVFEGSKYTEKCDIFSWAIVLWEVLSRKQPFKGIDN 218
>E2AK2_HUMAN (P19525) Interferon-induced, double-stranded RNA-activated protein| kinase (EC 2.7.11.1) (Interferon-inducible RNA-dependent protein kinase) (Protein kinase RNA-activated) (PKR) (p68 kinase) (P1/eIF-2A protein kinase) Length = 551 Score = 45.8 bits (107), Expect = 5e-05 Identities = 27/85 (31%), Positives = 45/85 (52%), Gaps = 3/85 (3%) Frame = +1 Query: 181 RGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPSFSPTRVSG---YRAP 351 +GV +IHS H ++K SN+ L + + ++ D GL T + TR G Y +P Sbjct: 400 KGVDYIHSK--KLIHRDLKPSNIFLVDTKQVKIGDFGLVTSLKNDGKRTRSKGTLRYMSP 457 Query: 352 EVTDIRRVSQKADVYSFGVLLLELL 426 E + ++ D+Y+ G++L ELL Sbjct: 458 EQISSQDYGKEVDLYALGLILAELL 482
>STK_HYDAT (P17713) Tyrosine-protein kinase STK (EC 2.7.10.2) (P57-STK)| Length = 509 Score = 45.8 bits (107), Expect = 5e-05 Identities = 30/105 (28%), Positives = 54/105 (51%), Gaps = 6/105 (5%) Frame = +1 Query: 163 IALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPSFSPTRVSG- 339 +A A G+A + + G H ++ + N+L+ ++Y +V+D GL L+ Sbjct: 340 MAAQVASGMAFLEAQGYI--HRDLAARNILVGENYICKVADFGLARLIEDDEYTAHEGAK 397 Query: 340 ----YRAPEVTDIRRVSQKADVYSFGVLLLELLT-GKAPTHAVVN 459 + APE R + K+DV+SFG+L+ E++T G+ P + N Sbjct: 398 FPIKWTAPEAALYNRFTIKSDVWSFGILMAEIVTKGRIPYPGMTN 442
>PAK6_HUMAN (Q9NQU5) Serine/threonine-protein kinase PAK 6 (EC 2.7.11.1)| (p21-activated kinase 6) (PAK-6) (PAK-5) Length = 681 Score = 45.8 bits (107), Expect = 5e-05 Identities = 29/106 (27%), Positives = 55/106 (51%), Gaps = 5/106 (4%) Frame = +1 Query: 139 LDWEARSAIALATARGVAHIHSTGPTASHGNIKSSNVLLTKSYEARVSDHGLPTLVGPSF 318 L+ E + + A + +A++H+ G H +IKS ++LLT ++SD G + Sbjct: 498 LNEEQIATVCEAVLQALAYLHAQG--VIHRDIKSDSILLTLDGRVKLSDFGFCAQISKDV 555 Query: 319 SPTRVS-----GYRAPEVTDIRRVSQKADVYSFGVLLLELLTGKAP 441 P R S + APEV + + D++S G++++E++ G+ P Sbjct: 556 -PKRKSLVGTPYWMAPEVISRSLYATEVDIWSLGIMVIEMVDGEPP 600 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 56,042,264 Number of Sequences: 219361 Number of extensions: 1054961 Number of successful extensions: 6178 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 5387 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5893 length of database: 80,573,946 effective HSP length: 102 effective length of database: 58,199,124 effective search space used: 2968155324 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
