Clone Name | bart59g08 |
---|---|
Clone Library Name | barley_pub |
>IDH3A_CAEEL (Q93714) Probable isocitrate dehydrogenase [NAD] subunit alpha,| mitochondrial precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) Length = 358 Score = 64.7 bits (156), Expect = 1e-10 Identities = 38/91 (41%), Positives = 51/91 (56%), Gaps = 5/91 (5%) Frame = +3 Query: 180 ARRTVTYMPRPGDGTPRPVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDV-----HG 344 A TV R G R VTLIPGDGIGP ++ +V+++ EA AP+ ++ DV Sbjct: 9 ASSTVGQSIRYSSGDVRRVTLIPGDGIGPEISASVQKIFEAADAPIAWDPVDVTPVKGRD 68 Query: 345 DMPAVPPAVIESIPRNKVCLKGGLATPVGGG 437 + +P IE + NKV LKG L TP+G G Sbjct: 69 GVFRIPSRCIELMHANKVGLKGPLETPIGKG 99
>IDH3A_DROME (Q9VWH4) Probable isocitrate dehydrogenase [NAD] subunit alpha,| mitochondrial precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) Length = 377 Score = 63.2 bits (152), Expect = 4e-10 Identities = 33/75 (44%), Positives = 46/75 (61%), Gaps = 5/75 (6%) Frame = +3 Query: 228 RPVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDV-----HGDMPAVPPAVIESIPRN 392 + VTLIPGDGIGP ++ AV+++ A + P+ +E DV +P A I+S+ N Sbjct: 48 KKVTLIPGDGIGPEISAAVQKIFTAANVPIEWEAVDVTPVRGPDGKFGIPQAAIDSVNTN 107 Query: 393 KVCLKGGLATPVGGG 437 K+ LKG L TPVG G Sbjct: 108 KIGLKGPLMTPVGKG 122
>IDH3A_BOVIN (P41563) Isocitrate dehydrogenase [NAD] subunit alpha,| mitochondrial precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) (Isocitrate dehydrogenase subunits 3/4) Length = 366 Score = 62.4 bits (150), Expect = 6e-10 Identities = 36/92 (39%), Positives = 51/92 (55%), Gaps = 5/92 (5%) Frame = +3 Query: 177 GARRTVTYMPRPGDGTPRPVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDV-----H 341 GA + R G + VTLIPGDGIGP ++ AV ++ +A AP+ +E +V Sbjct: 15 GAFHNQKQVTRGFAGGVKTVTLIPGDGIGPEISAAVMKIFDAAKAPIQWEERNVAAIQGP 74 Query: 342 GDMPAVPPAVIESIPRNKVCLKGGLATPVGGG 437 G +PP ES+ +NK+ LKG L TP+ G Sbjct: 75 GGKWMIPPEAKESMDKNKMGLKGPLKTPIAAG 106
>IDH3A_RAT (Q99NA5) Isocitrate dehydrogenase [NAD] subunit alpha,| mitochondrial precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) Length = 366 Score = 61.6 bits (148), Expect = 1e-09 Identities = 35/92 (38%), Positives = 51/92 (55%), Gaps = 5/92 (5%) Frame = +3 Query: 177 GARRTVTYMPRPGDGTPRPVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDV-----H 341 GA + R G + VTLIPGDGIGP ++ +V ++ +A AP+ +E +V Sbjct: 15 GAFHNTKQVTRGFAGGVQTVTLIPGDGIGPEISASVMKIFDAAKAPIQWEERNVTAIQGP 74 Query: 342 GDMPAVPPAVIESIPRNKVCLKGGLATPVGGG 437 G +PP ES+ +NK+ LKG L TP+ G Sbjct: 75 GGKWMIPPEAKESMDKNKMGLKGPLKTPIAAG 106
>IDH3A_MOUSE (Q9D6R2) Isocitrate dehydrogenase [NAD] subunit alpha,| mitochondrial precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) Length = 366 Score = 61.6 bits (148), Expect = 1e-09 Identities = 35/92 (38%), Positives = 51/92 (55%), Gaps = 5/92 (5%) Frame = +3 Query: 177 GARRTVTYMPRPGDGTPRPVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDV-----H 341 GA + R G + VTLIPGDGIGP ++ +V ++ +A AP+ +E +V Sbjct: 15 GAFHNTKQVTRGFAGGVQTVTLIPGDGIGPEISASVMKIFDAAKAPIQWEERNVTAIQGP 74 Query: 342 GDMPAVPPAVIESIPRNKVCLKGGLATPVGGG 437 G +PP ES+ +NK+ LKG L TP+ G Sbjct: 75 GGKWMIPPEAKESMDKNKMGLKGPLKTPIAAG 106
>IDH2_YEAST (P28241) Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial| precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) Length = 369 Score = 59.7 bits (143), Expect = 4e-09 Identities = 31/85 (36%), Positives = 50/85 (58%), Gaps = 5/85 (5%) Frame = +3 Query: 198 YMPRPGDGTPR-PVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVH----GDMPAVP 362 Y +P T + V+ I GDGIGP ++ +V+++ A + P+ +E+ DV + +P Sbjct: 26 YTGKPNPSTGKYTVSFIEGDGIGPEISKSVKKIFSAANVPIEWESCDVSPIFVNGLTTIP 85 Query: 363 PAVIESIPRNKVCLKGGLATPVGGG 437 ++SI +N V LKG LATP+G G Sbjct: 86 DPAVQSITKNLVALKGPLATPIGKG 110
>IDH3A_PONPY (Q5R678) Isocitrate dehydrogenase [NAD] subunit alpha,| mitochondrial precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) Length = 366 Score = 59.3 bits (142), Expect = 5e-09 Identities = 35/92 (38%), Positives = 50/92 (54%), Gaps = 5/92 (5%) Frame = +3 Query: 177 GARRTVTYMPRPGDGTPRPVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDV-----H 341 GA + R G + VTLIPGDGIGP ++ AV ++ +A AP+ +E +V Sbjct: 15 GAFHNPKQVTRGFTGGVQTVTLIPGDGIGPEISAAVMKIFDAAKAPIQWEERNVTAIQGP 74 Query: 342 GDMPAVPPAVIESIPRNKVCLKGGLATPVGGG 437 G +P ES+ +NK+ LKG L TP+ G Sbjct: 75 GGKWMIPSEAKESMDKNKMGLKGPLKTPIAAG 106
>IDH3A_HUMAN (P50213) Isocitrate dehydrogenase [NAD] subunit alpha,| mitochondrial precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) Length = 366 Score = 59.3 bits (142), Expect = 5e-09 Identities = 35/92 (38%), Positives = 50/92 (54%), Gaps = 5/92 (5%) Frame = +3 Query: 177 GARRTVTYMPRPGDGTPRPVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDV-----H 341 GA + R G + VTLIPGDGIGP ++ AV ++ +A AP+ +E +V Sbjct: 15 GAFHNPKQVTRGFTGGVQTVTLIPGDGIGPEISAAVMKIFDAAKAPIQWEERNVTAIQGP 74 Query: 342 GDMPAVPPAVIESIPRNKVCLKGGLATPVGGG 437 G +P ES+ +NK+ LKG L TP+ G Sbjct: 75 GGKWMIPSEAKESMDKNKMGLKGPLKTPIAAG 106
>IDH2_SCHPO (Q9USP8) Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial| precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) Length = 378 Score = 58.5 bits (140), Expect = 9e-09 Identities = 30/72 (41%), Positives = 43/72 (59%), Gaps = 4/72 (5%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVH----GDMPAVPPAVIESIPRNKVC 401 VT+I GDGIGP + +VE++ +A P+ +E V+ +P ES+ +NKV Sbjct: 48 VTMIAGDGIGPEIAQSVERIFKAAKVPIEWERVKVYPILKNGTTTIPDDAKESVRKNKVA 107 Query: 402 LKGGLATPVGGG 437 LKG LATP+G G Sbjct: 108 LKGPLATPIGKG 119
>IDH3A_MACFA (Q28480) Isocitrate dehydrogenase [NAD] subunit alpha,| mitochondrial precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) (Fragment) Length = 347 Score = 58.5 bits (140), Expect = 9e-09 Identities = 32/78 (41%), Positives = 46/78 (58%), Gaps = 5/78 (6%) Frame = +3 Query: 219 GTPRPVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDV-----HGDMPAVPPAVIESI 383 G + VTLIPGDGIGP ++ AV ++ +A AP+ +E +V G +P ES+ Sbjct: 10 GGVQTVTLIPGDGIGPEISAAVMKIFDAAKAPIQWEERNVTAIQGPGGKWMIPSEAKESM 69 Query: 384 PRNKVCLKGGLATPVGGG 437 +NK+ LKG L TP+ G Sbjct: 70 DKNKMGLKGPLKTPIAAG 87
>IDH_THET8 (P33197) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 496 Score = 57.8 bits (138), Expect = 2e-08 Identities = 33/74 (44%), Positives = 42/74 (56%), Gaps = 6/74 (8%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDV------HGDMPAVPPAVIESIPRNK 395 +T+IPGDGIGP A +V+EA AP+ +E + G VP IESI + + Sbjct: 22 ITVIPGDGIGPECVEATLKVLEAAKAPLAYEVREAGASVFRRGIASGVPQETIESIRKTR 81 Query: 396 VCLKGGLATPVGGG 437 V LKG L TPVG G Sbjct: 82 VVLKGPLETPVGYG 95
>IDH2_KLULA (O94230) Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial| precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) Length = 368 Score = 55.1 bits (131), Expect = 1e-07 Identities = 29/83 (34%), Positives = 45/83 (54%), Gaps = 10/83 (12%) Frame = +3 Query: 219 GTPRP------VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVH----GDMPAVPPA 368 G P P V+ I GDG+GP ++ +V+ + A P+ +E+ DV + +P Sbjct: 27 GKPNPKTGKYTVSFIEGDGVGPEISKSVKAIFSAAKVPIEWESCDVSPIFVNGLTTIPDP 86 Query: 369 VIESIPRNKVCLKGGLATPVGGG 437 + SI +N + LKG LATP+G G Sbjct: 87 AVASINKNLIALKGPLATPIGKG 109
>LEU3_SOLTU (P29696) 3-isopropylmalate dehydrogenase, chloroplast precursor (EC| 1.1.1.85) (Beta-IPM dehydrogenase) (IMDH) (3-IPM-DH) Length = 357 Score = 53.1 bits (126), Expect = 4e-07 Identities = 28/72 (38%), Positives = 42/72 (58%), Gaps = 5/72 (6%) Frame = +3 Query: 237 TLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHGDMPAVPPAV-----IESIPRNKVC 401 TL PGDGIGP + +V Q+ + P+ +E + V ++ + +ES+ RNKV Sbjct: 40 TLFPGDGIGPEIAESVRQIFKVAEVPIEWEEHYVGTEVDPRTNSFLTWESLESVRRNKVG 99 Query: 402 LKGGLATPVGGG 437 LKG +ATP+G G Sbjct: 100 LKGPMATPIGKG 111
>IDH1_KLULA (O94229) Isocitrate dehydrogenase [NAD] subunit 1, mitochondrial| precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) Length = 361 Score = 51.6 bits (122), Expect = 1e-06 Identities = 29/65 (44%), Positives = 40/65 (61%), Gaps = 1/65 (1%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHG-DMPAVPPAVIESIPRNKVCLKG 410 VTLIPGDG+G VT +V ++ E + P+ +ET D+ G + +ES+ RNKV LKG Sbjct: 32 VTLIPGDGVGKEVTDSVVKIFENENIPIDWETIDISGLENTENVQRAVESLKRNKVGLKG 91 Query: 411 GLATP 425 TP Sbjct: 92 IWHTP 96
>IDH1_SCHPO (O13696) Isocitrate dehydrogenase [NAD] subunit 1, mitochondrial| precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) Length = 356 Score = 50.1 bits (118), Expect(2) = 1e-06 Identities = 31/74 (41%), Positives = 39/74 (52%), Gaps = 6/74 (8%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHG------DMPAVPPAVIESIPRNK 395 VTLIPGDGIG + AV ++ + + P+ FE DV G I+S+ RNK Sbjct: 23 VTLIPGDGIGRETSNAVTEIFKTANVPIEFEEIDVTGMEKNNKSSGDALHEAIQSLKRNK 82 Query: 396 VCLKGGLATPVGGG 437 V LKG L TP G Sbjct: 83 VGLKGILFTPFEKG 96 Score = 20.8 bits (42), Expect(2) = 1e-06 Identities = 8/10 (80%), Positives = 10/10 (100%) Frame = +2 Query: 458 LRKELDLFAS 487 LRKELD++AS Sbjct: 105 LRKELDIYAS 114
>IDH1_YEAST (P28834) Isocitrate dehydrogenase [NAD] subunit 1, mitochondrial| precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) Length = 360 Score = 49.3 bits (116), Expect = 6e-06 Identities = 27/65 (41%), Positives = 39/65 (60%), Gaps = 1/65 (1%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDV-HGDMPAVPPAVIESIPRNKVCLKG 410 VTLIPGDG+G +T +V + EA + P+ +ET ++ D +ES+ RNK+ LKG Sbjct: 31 VTLIPGDGVGKEITDSVRTIFEAENIPIDWETINIKQTDHKEGVYEAVESLKRNKIGLKG 90 Query: 411 GLATP 425 TP Sbjct: 91 LWHTP 95
>IDH3B_RAT (Q68FX0) Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial| precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) Length = 385 Score = 44.7 bits (104), Expect(2) = 1e-05 Identities = 24/70 (34%), Positives = 39/70 (55%), Gaps = 4/70 (5%) Frame = +3 Query: 231 PVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHGDMPAVP----PAVIESIPRNKV 398 PVT++PGDG+GP + AV++V +A PV F+ + + V+ S+ NKV Sbjct: 50 PVTMLPGDGVGPELMHAVKEVFKAAAVPVEFKEHHLSEVQNMASEEKLEQVLSSMKENKV 109 Query: 399 CLKGGLATPV 428 + G + TP+ Sbjct: 110 AIIGKIYTPM 119 Score = 22.7 bits (47), Expect(2) = 1e-05 Identities = 9/12 (75%), Positives = 12/12 (100%) Frame = +2 Query: 452 MQLRKELDLFAS 487 MQLR++LDLFA+ Sbjct: 130 MQLRRKLDLFAN 141
>IDH1_AJECA (O13302) Isocitrate dehydrogenase [NAD] subunit 1, mitochondrial| precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) Length = 388 Score = 47.0 bits (110), Expect = 3e-05 Identities = 30/71 (42%), Positives = 40/71 (56%), Gaps = 6/71 (8%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHG------DMPAVPPAVIESIPRNK 395 VTLIPGDGIG V +V+ + +A + P+ +E DV G + I S+ RNK Sbjct: 54 VTLIPGDGIGTEVAESVKTIFKADNVPIEWEQVDVSGLDAGNKHSEDLFKESIASLKRNK 113 Query: 396 VCLKGGLATPV 428 + LKG L TPV Sbjct: 114 LGLKGILHTPV 124
>IDH3B_BOVIN (O77784) Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial| precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) (NAD(+)-isocitrate dehydrogenase subunit 1) (IDH1) Length = 385 Score = 45.4 bits (106), Expect = 8e-05 Identities = 24/70 (34%), Positives = 39/70 (55%), Gaps = 4/70 (5%) Frame = +3 Query: 231 PVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHGDMPAVP----PAVIESIPRNKV 398 PVT++PGDG+GP + AV++V +A PV F+ + + V+ S+ NKV Sbjct: 50 PVTMLPGDGVGPELMHAVKEVFKAASVPVEFQEHHLSEVQNMASEEKLEQVLSSMKENKV 109 Query: 399 CLKGGLATPV 428 + G + TP+ Sbjct: 110 AIIGKIHTPM 119
>IDH3B_MACFA (Q28479) Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial| precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) (Fragment) Length = 381 Score = 45.1 bits (105), Expect = 1e-04 Identities = 24/70 (34%), Positives = 39/70 (55%), Gaps = 4/70 (5%) Frame = +3 Query: 231 PVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHGDMPAVP----PAVIESIPRNKV 398 PVT++PGDG+GP + AV++V +A PV F+ + + V+ S+ NKV Sbjct: 48 PVTMLPGDGVGPELMHAVKEVFKAAAVPVEFQEHHLSEVQNMASEEKLEQVLSSMKENKV 107 Query: 399 CLKGGLATPV 428 + G + TP+ Sbjct: 108 AIIGKIHTPM 117
>IDH3B_PONPY (Q5RBT4) Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial| precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) Length = 385 Score = 45.1 bits (105), Expect = 1e-04 Identities = 24/70 (34%), Positives = 39/70 (55%), Gaps = 4/70 (5%) Frame = +3 Query: 231 PVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHGDMPAVP----PAVIESIPRNKV 398 PVT++PGDG+GP + AV++V +A PV F+ + + V+ S+ NKV Sbjct: 50 PVTMLPGDGVGPELMHAVKEVFKAAAVPVEFQEHHLSEVQNMASEEKLEQVLSSMKENKV 109 Query: 399 CLKGGLATPV 428 + G + TP+ Sbjct: 110 AIIGKIHTPM 119
>IDH3B_HUMAN (O43837) Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial| precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) Length = 385 Score = 45.1 bits (105), Expect = 1e-04 Identities = 24/70 (34%), Positives = 39/70 (55%), Gaps = 4/70 (5%) Frame = +3 Query: 231 PVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHGDMPAVP----PAVIESIPRNKV 398 PVT++PGDG+GP + AV++V +A PV F+ + + V+ S+ NKV Sbjct: 50 PVTMLPGDGVGPELMHAVKEVFKAAAVPVEFQEHHLSEVQNMASEEKLEQVLSSMKENKV 109 Query: 399 CLKGGLATPV 428 + G + TP+ Sbjct: 110 AIIGKIHTPM 119
>IDH3G_RAT (P41565) Isocitrate dehydrogenase [NAD] subunit gamma,| mitochondrial precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) Length = 393 Score = 43.1 bits (100), Expect = 4e-04 Identities = 33/96 (34%), Positives = 48/96 (50%), Gaps = 2/96 (2%) Frame = +3 Query: 141 VASAPSLPGHGGGARRTVTYMPRPGDGTPRPVTLIPGDGIGPLVTGAVEQVMEAMHAPVY 320 V +A P +++T+ P G VT+IPGDGIGP + V+ V PV Sbjct: 28 VLAAHEAPRRSISSQQTIP--PSAKYGGRHTVTMIPGDGIGPELMLHVKSVFRHACVPVD 85 Query: 321 FETYDV--HGDMPAVPPAVIESIPRNKVCLKGGLAT 422 FE V + D + A++ +I RN+V LKG + T Sbjct: 86 FEEVHVSSNADEEDIRNAIM-AIRRNRVALKGNIET 120
>IDH3G_MACFA (P41564) Isocitrate dehydrogenase [NAD] subunit gamma,| mitochondrial precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) (Fragment) Length = 355 Score = 42.7 bits (99), Expect = 5e-04 Identities = 30/78 (38%), Positives = 40/78 (51%), Gaps = 2/78 (2%) Frame = +3 Query: 195 TYMPRPGDGTPRPVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDV--HGDMPAVPPA 368 T P G VT+IPGDGIGP + V+ V PV FE V + D + A Sbjct: 6 TIPPSAKYGGRHTVTMIPGDGIGPELMLHVKSVFRHACVPVDFEEVHVSSNADEEDIRNA 65 Query: 369 VIESIPRNKVCLKGGLAT 422 ++ +I RN+V LKG + T Sbjct: 66 IM-AIRRNRVALKGNIET 82
>IDH3G_MOUSE (P70404) Isocitrate dehydrogenase [NAD] subunit gamma,| mitochondrial precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) Length = 393 Score = 42.7 bits (99), Expect = 5e-04 Identities = 30/78 (38%), Positives = 40/78 (51%), Gaps = 2/78 (2%) Frame = +3 Query: 195 TYMPRPGDGTPRPVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDV--HGDMPAVPPA 368 T P G VT+IPGDGIGP + V+ V PV FE V + D + A Sbjct: 44 TIPPSAKYGGRHTVTMIPGDGIGPELMLHVKSVFRHACVPVDFEEVHVSSNADEEDIRNA 103 Query: 369 VIESIPRNKVCLKGGLAT 422 ++ +I RN+V LKG + T Sbjct: 104 IM-AIRRNRVALKGNIET 120
>IDH3G_HUMAN (P51553) Isocitrate dehydrogenase [NAD] subunit gamma,| mitochondrial precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) Length = 393 Score = 42.7 bits (99), Expect = 5e-04 Identities = 30/78 (38%), Positives = 40/78 (51%), Gaps = 2/78 (2%) Frame = +3 Query: 195 TYMPRPGDGTPRPVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDV--HGDMPAVPPA 368 T P G VT+IPGDGIGP + V+ V PV FE V + D + A Sbjct: 44 TIPPSAKYGGRHTVTMIPGDGIGPELMLHVKSVFRHACVPVDFEEVHVSSNADEEDIRNA 103 Query: 369 VIESIPRNKVCLKGGLAT 422 ++ +I RN+V LKG + T Sbjct: 104 IM-AIRRNRVALKGNIET 120
>IDH_RICCN (Q92IR7) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 483 Score = 42.4 bits (98), Expect = 7e-04 Identities = 25/75 (33%), Positives = 36/75 (48%), Gaps = 6/75 (8%) Frame = +3 Query: 231 PVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHGDM------PAVPPAVIESIPRN 392 P+T+ GDGIGP + AV ++ A + ET +V + + ESI R Sbjct: 6 PITIAYGDGIGPEIMEAVLYILRKAEARIRLETIEVGEKLYKKHYTSGISEESWESIQRT 65 Query: 393 KVCLKGGLATPVGGG 437 + LK + TP GGG Sbjct: 66 GIILKAPITTPQGGG 80
>IDH_ANASP (P50214) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 473 Score = 41.6 bits (96), Expect = 0.001 Identities = 27/83 (32%), Positives = 40/83 (48%), Gaps = 14/83 (16%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVY--------FETY------DVHGDMPAVPPAV 371 + I GDG G + A E+V++A A Y F+ Y D++G +P Sbjct: 29 IPFIRGDGTGIDIWPATEKVLDAAVAKAYQGKRKISWFKVYAGDEACDLYGTYQYLPEDT 88 Query: 372 IESIPRNKVCLKGGLATPVGGGV 440 + +I V +KG L TPVGGG+ Sbjct: 89 LTAIREYGVAIKGPLTTPVGGGI 111
>IDH3B_CAEEL (Q93353) Probable isocitrate dehydrogenase [NAD] subunit beta,| mitochondrial precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) Length = 379 Score = 41.2 bits (95), Expect = 0.002 Identities = 35/109 (32%), Positives = 53/109 (48%), Gaps = 12/109 (11%) Frame = +3 Query: 126 LLRRLVAS----APSLPG--HGGGARRTVTYMPRPGDGTPRP--VTLIPGDGIGPLVTGA 281 +L R V+S AP G + +R+ PRP + VT+IPGDG+GP + Sbjct: 1 MLSRTVSSLSRVAPQTLGAVNAASSRQYSITAPRPPTELNQKLKVTIIPGDGVGPELIYT 60 Query: 282 VEQVMEAMHAPVYFETY---DVHGDMPAVPPAVIESIPR-NKVCLKGGL 416 V+ +++ P+ FE +VH + +ESI R N V LKG + Sbjct: 61 VQDIVKQTGIPIEFEEIFLSEVHYTRSSSIENAVESIGRNNNVALKGAI 109
>IDH_ECOLI (P08200) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 416 Score = 40.4 bits (93), Expect = 0.003 Identities = 28/83 (33%), Positives = 40/83 (48%), Gaps = 14/83 (16%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVY--------FETY------DVHGDMPAVPPAV 371 + I GDGIG VT A+ +V++A Y E Y V+G +P Sbjct: 29 IPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERKISWMEIYTGEKSTQVYGQDVWLPAET 88 Query: 372 IESIPRNKVCLKGGLATPVGGGV 440 ++ I +V +KG L TPVGGG+ Sbjct: 89 LDLIREYRVAIKGPLTTPVGGGI 111
>IDH_STAES (Q8CNX4) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 422 Score = 40.0 bits (92), Expect = 0.003 Identities = 25/83 (30%), Positives = 39/83 (46%), Gaps = 14/83 (16%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYF--------------ETYDVHGDMPAVPPAV 371 + I GDGIGP + A +V++A Y + YD G+ +P Sbjct: 21 IPFIIGDGIGPDIWKAASRVIDAAVEKAYNGEKRIEWKEVLAGQKAYDETGEW--LPQET 78 Query: 372 IESIPRNKVCLKGGLATPVGGGV 440 +E+I + +KG L TP+GGG+ Sbjct: 79 LETIKEYLIAVKGPLTTPIGGGI 101
>IDH_STAEQ (Q5HNL1) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 422 Score = 40.0 bits (92), Expect = 0.003 Identities = 25/83 (30%), Positives = 39/83 (46%), Gaps = 14/83 (16%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYF--------------ETYDVHGDMPAVPPAV 371 + I GDGIGP + A +V++A Y + YD G+ +P Sbjct: 21 IPFIIGDGIGPDIWKAASRVIDAAVEKAYNGEKRIEWKEVLAGQKAYDETGEW--LPQET 78 Query: 372 IESIPRNKVCLKGGLATPVGGGV 440 +E+I + +KG L TP+GGG+ Sbjct: 79 LETIKEYLIAVKGPLTTPIGGGI 101
>IDH3A_PIG (P56471) Isocitrate dehydrogenase [NAD] subunit alpha,| mitochondrial (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) (Fragments) Length = 90 Score = 39.7 bits (91), Expect = 0.004 Identities = 17/33 (51%), Positives = 24/33 (72%) Frame = +3 Query: 219 GTPRPVTLIPGDGIGPLVTGAVEQVMEAMHAPV 317 G + VTLIPGDGIGP ++ AV ++ +A AP+ Sbjct: 2 GGVKTVTLIPGDGIGPEISAAVMKIFDAAKAPI 34
>IDH_STAAW (Q8NW61) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 422 Score = 38.1 bits (87), Expect = 0.013 Identities = 23/83 (27%), Positives = 39/83 (46%), Gaps = 14/83 (16%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYF--------------ETYDVHGDMPAVPPAV 371 + I GDGIGP + A +V++A Y + +D G+ +P Sbjct: 21 IPFIIGDGIGPDIWKAASRVIDAAVEKAYNGEKRIEWKEVLAGQKAFDTTGEW--LPQET 78 Query: 372 IESIPRNKVCLKGGLATPVGGGV 440 +++I + +KG L TP+GGG+ Sbjct: 79 LDTIKEYLIAVKGPLTTPIGGGI 101
>IDH_STAAS (Q6G8N2) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 422 Score = 38.1 bits (87), Expect = 0.013 Identities = 23/83 (27%), Positives = 39/83 (46%), Gaps = 14/83 (16%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYF--------------ETYDVHGDMPAVPPAV 371 + I GDGIGP + A +V++A Y + +D G+ +P Sbjct: 21 IPFIIGDGIGPDIWKAASRVIDAAVEKAYNGEKRIEWKEVLAGQKAFDTTGEW--LPQET 78 Query: 372 IESIPRNKVCLKGGLATPVGGGV 440 +++I + +KG L TP+GGG+ Sbjct: 79 LDTIKEYLIAVKGPLTTPIGGGI 101
>IDH_STAAR (Q6GG12) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 422 Score = 38.1 bits (87), Expect = 0.013 Identities = 23/83 (27%), Positives = 39/83 (46%), Gaps = 14/83 (16%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYF--------------ETYDVHGDMPAVPPAV 371 + I GDGIGP + A +V++A Y + +D G+ +P Sbjct: 21 IPFIIGDGIGPDIWKAASRVIDAAVEKAYNGEKRIEWKEVLAGQKAFDTTGEW--LPQET 78 Query: 372 IESIPRNKVCLKGGLATPVGGGV 440 +++I + +KG L TP+GGG+ Sbjct: 79 LDTIKEYLIAVKGPLTTPIGGGI 101
>IDH_STAAN (P99167) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 422 Score = 38.1 bits (87), Expect = 0.013 Identities = 23/83 (27%), Positives = 39/83 (46%), Gaps = 14/83 (16%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYF--------------ETYDVHGDMPAVPPAV 371 + I GDGIGP + A +V++A Y + +D G+ +P Sbjct: 21 IPFIIGDGIGPDIWKAASRVIDAAVEKAYNGEKRIEWKEVLAGQKAFDTTGEW--LPQET 78 Query: 372 IESIPRNKVCLKGGLATPVGGGV 440 +++I + +KG L TP+GGG+ Sbjct: 79 LDTIKEYLIAVKGPLTTPIGGGI 101
>IDH_STAAM (P65099) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 422 Score = 38.1 bits (87), Expect = 0.013 Identities = 23/83 (27%), Positives = 39/83 (46%), Gaps = 14/83 (16%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYF--------------ETYDVHGDMPAVPPAV 371 + I GDGIGP + A +V++A Y + +D G+ +P Sbjct: 21 IPFIIGDGIGPDIWKAASRVIDAAVEKAYNGEKRIEWKEVLAGQKAFDTTGEW--LPQET 78 Query: 372 IESIPRNKVCLKGGLATPVGGGV 440 +++I + +KG L TP+GGG+ Sbjct: 79 LDTIKEYLIAVKGPLTTPIGGGI 101
>IDH_STAAC (Q5HF79) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 422 Score = 38.1 bits (87), Expect = 0.013 Identities = 23/83 (27%), Positives = 39/83 (46%), Gaps = 14/83 (16%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYF--------------ETYDVHGDMPAVPPAV 371 + I GDGIGP + A +V++A Y + +D G+ +P Sbjct: 21 IPFIIGDGIGPDIWKAASRVIDAAVEKAYNGEKRIEWKEVLAGQKAFDTTGEW--LPQET 78 Query: 372 IESIPRNKVCLKGGLATPVGGGV 440 +++I + +KG L TP+GGG+ Sbjct: 79 LDTIKEYLIAVKGPLTTPIGGGI 101
>IDH_SYNY3 (P80046) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 475 Score = 37.7 bits (86), Expect = 0.017 Identities = 26/83 (31%), Positives = 37/83 (44%), Gaps = 14/83 (16%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVY--------FETY------DVHGDMPAVPPAV 371 + I GDG G + A E V+ A A Y F+ Y +++G P Sbjct: 29 IPYIRGDGTGVDIWPATELVINAAIAKAYGGREEINWFKVYAGDEACELYGTYQIFPEDT 88 Query: 372 IESIPRNKVCLKGGLATPVGGGV 440 + +I V +KG L TPVGGG+ Sbjct: 89 LTAIKEYGVAIKGPLTTPVGGGI 111
>IDH_BACSU (P39126) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 423 Score = 37.0 bits (84), Expect = 0.028 Identities = 24/83 (28%), Positives = 37/83 (44%), Gaps = 14/83 (16%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYF--------------ETYDVHGDMPAVPPAV 371 + I GDG GP + A +V+EA Y + Y+ G+ +P Sbjct: 22 IPFIEGDGTGPDIWNAASKVLEAAVEKAYKGEKKITWKEVYAGEKAYNKTGEW--LPAET 79 Query: 372 IESIPRNKVCLKGGLATPVGGGV 440 ++ I + +KG L TPVGGG+ Sbjct: 80 LDVIREYFIAIKGPLTTPVGGGI 102
>IDH1_COLMA (P41560) Isocitrate dehydrogenase [NADP] 1 (EC 1.1.1.42)| (Oxalosuccinate decarboxylase 1) (IDH-I) (NADP(+)-specific ICDH 1) (IDP-1) Length = 414 Score = 36.6 bits (83), Expect = 0.037 Identities = 27/83 (32%), Positives = 38/83 (45%), Gaps = 14/83 (16%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVY-----FETYDVHGDMPA---------VPPAV 371 + I GDGIG VT + +V+ A A Y E +V+ A +P Sbjct: 28 IPYIEGDGIGVDVTPPMLKVVNAAVAKAYGGDRKIEWLEVYAGEKATKMYDSETWLPEET 87 Query: 372 IESIPRNKVCLKGGLATPVGGGV 440 + + KV +KG L TPVGGG+ Sbjct: 88 LNILQEYKVSIKGPLTTPVGGGM 110
>IDH_CALNO (P96318) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 429 Score = 36.6 bits (83), Expect = 0.037 Identities = 25/80 (31%), Positives = 38/80 (47%), Gaps = 12/80 (15%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFET-----YDVHGDMPA-------VPPAVIE 377 V GDGIGP + + ++V++A Y T ++V A +P ++ Sbjct: 35 VAYFKGDGIGPEIVESAKKVLDAAVDKAYGGTRRIVWWEVTAGEEAQKECGSLLPDGTLQ 94 Query: 378 SIPRNKVCLKGGLATPVGGG 437 + +V LKG L TPVGGG Sbjct: 95 AFKLARVNLKGPLTTPVGGG 114
>IDH_RICPR (Q9ZDR0) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 483 Score = 36.6 bits (83), Expect = 0.037 Identities = 22/75 (29%), Positives = 34/75 (45%), Gaps = 6/75 (8%) Frame = +3 Query: 231 PVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHGDM------PAVPPAVIESIPRN 392 P+T+ GDGIGP + AV ++ A + ET +V + + + I R Sbjct: 6 PITIAYGDGIGPEIMEAVLYILRKAEARISLETIEVGEKLYKKHYTSGISEESWDVIQRT 65 Query: 393 KVCLKGGLATPVGGG 437 + LK + TP GG Sbjct: 66 GIILKAPITTPQSGG 80
>LEU3_MYCTU (P95313) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 336 Score = 36.2 bits (82), Expect = 0.048 Identities = 20/69 (28%), Positives = 34/69 (49%), Gaps = 5/69 (7%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDV-----HGDMPAVPPAVIESIPRNKV 398 + +I GDGIGP VT +V++A+ V +YD+ H +P +V+ + + Sbjct: 3 LAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNHDA 62 Query: 399 CLKGGLATP 425 L G + P Sbjct: 63 ILLGAIGDP 71
>LEU3_MYCBO (P94929) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 336 Score = 36.2 bits (82), Expect = 0.048 Identities = 20/69 (28%), Positives = 34/69 (49%), Gaps = 5/69 (7%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDV-----HGDMPAVPPAVIESIPRNKV 398 + +I GDGIGP VT +V++A+ V +YD+ H +P +V+ + + Sbjct: 3 LAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNHDA 62 Query: 399 CLKGGLATP 425 L G + P Sbjct: 63 ILLGAIGDP 71
>IDH_RICTY (Q68XA5) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 483 Score = 36.2 bits (82), Expect = 0.048 Identities = 22/75 (29%), Positives = 33/75 (44%), Gaps = 6/75 (8%) Frame = +3 Query: 231 PVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHGDM------PAVPPAVIESIPRN 392 P+T+ GDGIGP + AV ++ A + ET +V + + I R Sbjct: 6 PITIAYGDGIGPEIMDAVLYILRQAEARISLETIEVGEKLYKKHYTSGISEESWNVIQRT 65 Query: 393 KVCLKGGLATPVGGG 437 + LK + TP GG Sbjct: 66 GIILKAPITTPQSGG 80
>IDH_ARCFU (O29610) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 412 Score = 36.2 bits (82), Expect = 0.048 Identities = 26/74 (35%), Positives = 38/74 (51%), Gaps = 11/74 (14%) Frame = +3 Query: 249 GDGIGPLVTGAVEQVMEAM-----HAPVYFETY------DVHGDMPAVPPAVIESIPRNK 395 GDGIG V A +V++A V+F+ Y ++G+ +P + +I + Sbjct: 35 GDGIGKDVVPAAIRVLDAAADKIGKEVVWFQVYAGEDAYKLYGNY--LPDDTLNAIKEFR 92 Query: 396 VCLKGGLATPVGGG 437 V LKG L TPVGGG Sbjct: 93 VALKGPLTTPVGGG 106
>LEU3_DEIRA (Q9RTH9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 352 Score = 35.8 bits (81), Expect = 0.063 Identities = 21/48 (43%), Positives = 26/48 (54%), Gaps = 7/48 (14%) Frame = +3 Query: 225 PRPVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFE-------TYDVHGD 347 P+ +TL PGDGIGP VT A QV+ + V E YD HG+ Sbjct: 2 PKVITL-PGDGIGPEVTAAAVQVLREVAPDVTVEEHAIGGGAYDAHGE 48
>LEU3_MYCPA (Q73VI1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 336 Score = 34.3 bits (77), Expect = 0.18 Identities = 21/69 (30%), Positives = 34/69 (49%), Gaps = 5/69 (7%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDV-----HGDMPAVPPAVIESIPRNKV 398 + +I GDGIGP VT +V++A+ V YD+ H +P +VI+ + + Sbjct: 3 LAVIGGDGIGPEVTAEALKVLDAVLPGVDKTEYDLGARRYHATGELLPDSVIDELRAHDA 62 Query: 399 CLKGGLATP 425 L G + P Sbjct: 63 ILLGAIGDP 71
>IDH_STRSL (Q59985) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 391 Score = 34.3 bits (77), Expect = 0.18 Identities = 26/83 (31%), Positives = 37/83 (44%), Gaps = 14/83 (16%) Frame = +3 Query: 234 VTLIPGDGIG--------PLVTGAVEQVMEAMHAPVYFE------TYDVHGDMPAVPPAV 371 + I GDG+G + AVE E + E YD G+ +P Sbjct: 20 IPFIEGDGVGHDIWKNAQAIFDKAVEVAYEGKRHIEWQELLAGKKAYDKTGEW--LPKET 77 Query: 372 IESIPRNKVCLKGGLATPVGGGV 440 +E+I + V +KG L TPVGGG+ Sbjct: 78 LEAIRESLVAIKGPLETPVGGGI 100
>LEU3_CHRVO (Q7NUC2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 354 Score = 34.3 bits (77), Expect = 0.18 Identities = 16/47 (34%), Positives = 25/47 (53%), Gaps = 10/47 (21%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVMEAM----------HAPVYFETYDVHG 344 + ++PGDGIGP + E+V+E + HAP+ YD +G Sbjct: 3 IAILPGDGIGPEIIAQAERVLEVLRRDGLKIETEHAPLGGAAYDQYG 49
>LEU3_BORPE (Q7VY73) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 358 Score = 34.3 bits (77), Expect = 0.18 Identities = 19/66 (28%), Positives = 32/66 (48%), Gaps = 5/66 (7%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHGDM-----PAVPPAVIESIPRNKV 398 + ++PGDGIGP + E+V++A+ P+ V G +PPA +E + Sbjct: 5 IAVLPGDGIGPEIVEQAERVLKALDLPLELRQAPVGGAAFDQFEHPLPPATLELAQGSHA 64 Query: 399 CLKGGL 416 L G + Sbjct: 65 VLFGAV 70
>LEU3_BORPA (Q7W929) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 358 Score = 34.3 bits (77), Expect = 0.18 Identities = 19/66 (28%), Positives = 32/66 (48%), Gaps = 5/66 (7%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHGDM-----PAVPPAVIESIPRNKV 398 + ++PGDGIGP + E+V++A+ P+ V G +PPA +E + Sbjct: 5 IAVLPGDGIGPEIVEQAERVLKALDLPLELRQAPVGGAAFDQFEHPLPPATLELAQGSHA 64 Query: 399 CLKGGL 416 L G + Sbjct: 65 VLFGAV 70
>LEU3_BORBR (Q7WKH4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 358 Score = 34.3 bits (77), Expect = 0.18 Identities = 19/66 (28%), Positives = 32/66 (48%), Gaps = 5/66 (7%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHGDM-----PAVPPAVIESIPRNKV 398 + ++PGDGIGP + E+V++A+ P+ V G +PPA +E + Sbjct: 5 IAVLPGDGIGPEIVEQAERVLKALDLPLELRQAPVGGAAFDQFEHPLPPATLELAQGSHA 64 Query: 399 CLKGGL 416 L G + Sbjct: 65 VLFGAV 70
>LEU3_SYNPX (Q7U840) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 357 Score = 33.9 bits (76), Expect = 0.24 Identities = 15/31 (48%), Positives = 20/31 (64%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFE 326 V L+PGDGIGP +T Q++EA+ FE Sbjct: 6 VVLLPGDGIGPEITAVARQLLEAVSQRHGFE 36
>IDH_HELPJ (Q9ZN36) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 425 Score = 33.5 bits (75), Expect = 0.31 Identities = 24/89 (26%), Positives = 40/89 (44%), Gaps = 21/89 (23%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVY-----------------FETYDVHGDMPA-- 356 + I GDGIG +T A+ +V+++ Y ++ + H ++ Sbjct: 32 IPFIEGDGIGSDITPAMIKVVDSAVQKAYKGEKKIAWYEVFVGEKCYQKFKDHKELSPEE 91 Query: 357 --VPPAVIESIPRNKVCLKGGLATPVGGG 437 + P IE+I KV +KG L TP+G G Sbjct: 92 QWLLPDTIEAINHYKVSIKGPLTTPIGEG 120
>IDH_AQUAE (O67480) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 426 Score = 33.1 bits (74), Expect = 0.41 Identities = 23/81 (28%), Positives = 37/81 (45%), Gaps = 12/81 (14%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVH------GDMPA------VPPAVIE 377 + I GDGIGP +T A+ ++ Y + ++ GD +P ++ Sbjct: 41 IPFIEGDGIGPEITQAMLLIINTAVEKTYNGSKKIYWVELLAGDKAEEKTGERLPQETLD 100 Query: 378 SIPRNKVCLKGGLATPVGGGV 440 + + V +KG L TPVG GV Sbjct: 101 VLKESIVGIKGPLGTPVGKGV 121
>IDH_HELPY (P56063) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 425 Score = 32.7 bits (73), Expect = 0.53 Identities = 25/89 (28%), Positives = 40/89 (44%), Gaps = 21/89 (23%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVY--------------------FETY-DVHGDM 350 + I GDGIG +T A+ +V+++ Y F+ Y ++ + Sbjct: 32 IPFIEGDGIGSDITPAMIKVVDSAVQKAYKGEKKIAWYEVFVGEKCYQKFKDYKELSPEE 91 Query: 351 PAVPPAVIESIPRNKVCLKGGLATPVGGG 437 + P IE+I KV +KG L TP+G G Sbjct: 92 QWLLPDTIEAINHYKVSIKGPLTTPIGEG 120
>LRP11_HUMAN (Q86VZ4) Low-density lipoprotein receptor-related protein 11| precursor Length = 500 Score = 32.7 bits (73), Expect = 0.53 Identities = 25/88 (28%), Positives = 38/88 (43%), Gaps = 5/88 (5%) Frame = -3 Query: 478 EVELLAELHVREETPPPTGVARPPLRQTLLRGMDSMTAGGT-----AGMSPWTSYVSK*T 314 E+EL A +E+ P P + ++R DS+ AG + A + W V+ Sbjct: 76 ELELRAGGGPQEDCPGPGSGGYSAMPDAIIRTKDSLAAGASFLRAPAAVRGWRQCVA--- 132 Query: 313 GACMASMTCSTAPVTRGPMPSPGMSVTG 230 AC + CS A V P+P +V G Sbjct: 133 -ACCSEPRCSVAVVELPRRPAPPAAVLG 159
>LEU3_PROMT (Q46LE2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 359 Score = 32.7 bits (73), Expect = 0.53 Identities = 12/31 (38%), Positives = 20/31 (64%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFE 326 +TL+PGDGIGP +T ++++ + FE Sbjct: 6 ITLLPGDGIGPEITNVTHKILDLVSRKFGFE 36
>LEU3_SHIBS (Q326G2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 32.7 bits (73), Expect = 0.53 Identities = 22/75 (29%), Positives = 33/75 (44%), Gaps = 11/75 (14%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVMEAM-----------HAPVYFETYDVHGDMPAVPPAVIES 380 + ++PGDGIGP V +V++A+ H V D HG +PPA +E Sbjct: 7 IAVLPGDGIGPEVMTQALKVLDAVRNRFAMRITTSHYDVGGAAIDNHGQ--PLPPATVEG 64 Query: 381 IPRNKVCLKGGLATP 425 + L G + P Sbjct: 65 CEQADAVLFGSVGGP 79
>LEU3_NOCFA (Q5YRX2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 335 Score = 32.7 bits (73), Expect = 0.53 Identities = 19/69 (27%), Positives = 32/69 (46%), Gaps = 5/69 (7%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDV-----HGDMPAVPPAVIESIPRNKV 398 + +IPGDGIGP V +V++ + V YD+ H +P +V+ + + Sbjct: 3 LAVIPGDGIGPEVIAEALKVLDVVVPGVEKTEYDLGAKRYHATGEILPDSVLPELREHDA 62 Query: 399 CLKGGLATP 425 L G + P Sbjct: 63 ILLGAIGDP 71
>LEU3_THIDA (Q3SHL3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 353 Score = 32.7 bits (73), Expect = 0.53 Identities = 21/74 (28%), Positives = 33/74 (44%), Gaps = 10/74 (13%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMH----------APVYFETYDVHGDMPAVPPAVIESI 383 + ++PGDGIGP + +V+EA+ AP+ YD GD +P A ++ Sbjct: 3 IAVLPGDGIGPEIISQAVKVLEALKSEGAKIEMETAPIGGAGYDAAGD--PLPEATLKLA 60 Query: 384 PRNKVCLKGGLATP 425 L G + P Sbjct: 61 READAVLLGAVGGP 74
>LEU3_ECOLI (P30125) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 362 Score = 32.7 bits (73), Expect = 0.53 Identities = 22/75 (29%), Positives = 33/75 (44%), Gaps = 11/75 (14%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVMEAM-----------HAPVYFETYDVHGDMPAVPPAVIES 380 + ++PGDGIGP V +V++A+ H V D HG +PPA +E Sbjct: 6 IAVLPGDGIGPEVMTQALKVLDAVRNRFAMRITTSHYDVGGAAIDNHGQ--PLPPATVEG 63 Query: 381 IPRNKVCLKGGLATP 425 + L G + P Sbjct: 64 CEQADAVLFGSVGGP 78
>LEU3_ECOL6 (Q8FL76) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 362 Score = 32.7 bits (73), Expect = 0.53 Identities = 22/75 (29%), Positives = 33/75 (44%), Gaps = 11/75 (14%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVMEAM-----------HAPVYFETYDVHGDMPAVPPAVIES 380 + ++PGDGIGP V +V++A+ H V D HG +PPA +E Sbjct: 6 IAVLPGDGIGPEVMTQALKVLDAVRNRFAMRITTSHYDVGGAAIDNHGQ--PLPPATVEG 63 Query: 381 IPRNKVCLKGGLATP 425 + L G + P Sbjct: 64 CEQADAVLFGSVGGP 78
>LEU3_ECO57 (Q8X9Z9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 362 Score = 32.7 bits (73), Expect = 0.53 Identities = 22/75 (29%), Positives = 33/75 (44%), Gaps = 11/75 (14%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVMEAM-----------HAPVYFETYDVHGDMPAVPPAVIES 380 + ++PGDGIGP V +V++A+ H V D HG +PPA +E Sbjct: 6 IAVLPGDGIGPEVMTQALKVLDAVRNRFAMRITTSHYDVGGAAIDNHGQ--PLPPATVEG 63 Query: 381 IPRNKVCLKGGLATP 425 + L G + P Sbjct: 64 CEQADAVLFGSVGGP 78
>LEU3_CHLTE (P59028) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 352 Score = 32.3 bits (72), Expect = 0.70 Identities = 19/50 (38%), Positives = 23/50 (46%), Gaps = 11/50 (22%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFE-----------TYDVHGDM 350 + IPGDGIGP V V+ A+ FE +YDVHG M Sbjct: 5 IVSIPGDGIGPEVVAGALDVLNAVAKKHGFEVSVEEHLFGGASYDVHGSM 54
>RSMB_DROME (Q05856) Small nuclear ribonucleoprotein-associated protein B| (snRNP-B) (Sm protein B) (Sm-B) (SmB) Length = 199 Score = 32.3 bits (72), Expect = 0.70 Identities = 38/128 (29%), Positives = 46/128 (35%), Gaps = 21/128 (16%) Frame = -3 Query: 472 ELLAELHVREETPPPTGVARPPLR---------QTLLRGMDSMTAGGTAGMSPWTSYVSK 320 E + L V PP G+ R P+ + RGM + AG+ V Sbjct: 75 ENIVSLTVEGPPPPEEGLPRVPIPGAAPGPGIGRVAGRGMPINLSAVPAGLQGPVRGVG- 133 Query: 319 *TGACMASMTCSTAPVTRGPM---PSPGM---------SVTGRGVPSPGRGM*VTVRRAP 176 G M V R PM P PGM GRG P P RG ++ R Sbjct: 134 --GPAQQHMAPMGRGVPRAPMMGAPPPGMIPGGMPSMPGNMGRGAPPPMRGPPPSMIRGA 191 Query: 175 PPWPGRDG 152 PP PGR G Sbjct: 192 PP-PGRGG 198
>LEU3_ARCFU (O29627) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 326 Score = 32.3 bits (72), Expect = 0.70 Identities = 18/66 (27%), Positives = 31/66 (46%), Gaps = 5/66 (7%) Frame = +3 Query: 228 RPVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHGDM-----PAVPPAVIESIPRN 392 + + +IPGDGIG V A ++E + P + YD + A+P +E+ ++ Sbjct: 2 KKIVVIPGDGIGKEVMEAAMLILEKLDLPFEYSYYDAGDEALEKYGKALPDETLEACRKS 61 Query: 393 KVCLKG 410 L G Sbjct: 62 DAVLFG 67
>LEU3_AGRT5 (P24404) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 370 Score = 32.3 bits (72), Expect = 0.70 Identities = 26/84 (30%), Positives = 36/84 (42%), Gaps = 11/84 (13%) Frame = +3 Query: 222 TPRPVTLIPGDGIGPLVTGAVEQVMEAMHAP-----------VYFETYDVHGDMPAVPPA 368 T R + L+PGDGIGP V +++E M++ V YD HG A+ A Sbjct: 2 TVRSLFLLPGDGIGPEAMTEVRKLIEYMNSAHNAGFTVSEGLVGGSAYDAHG--VAISDA 59 Query: 369 VIESIPRNKVCLKGGLATPVGGGV 440 +E L G + P GV Sbjct: 60 DMEKALAADAILFGAVGGPKWDGV 83
>DLPA_LEGPH (Q48806) Protein dlpA| Length = 615 Score = 32.0 bits (71), Expect = 0.91 Identities = 20/71 (28%), Positives = 31/71 (43%), Gaps = 5/71 (7%) Frame = +3 Query: 225 PRPVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHGDM-----PAVPPAVIESIPR 389 P + ++PGDGIG VT A V E + PV D+ + A+P + I Sbjct: 6 PIKIAVLPGDGIGIEVTEATLPVFEVLDVPVILNYGDIGWEFWKKEGAAIPSRTWQLIAS 65 Query: 390 NKVCLKGGLAT 422 + L G + + Sbjct: 66 SDTVLLGAITS 76
>LEU3_SHISS (Q3Z5T7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 32.0 bits (71), Expect = 0.91 Identities = 22/75 (29%), Positives = 32/75 (42%), Gaps = 11/75 (14%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVMEAM-----------HAPVYFETYDVHGDMPAVPPAVIES 380 + ++PGDGIGP V +V+ A+ H V D HG +PPA +E Sbjct: 7 IAVLPGDGIGPEVMTQALKVLNAVRNRFAMRITTSHYDVGGAAIDNHGQ--PLPPATVEG 64 Query: 381 IPRNKVCLKGGLATP 425 + L G + P Sbjct: 65 CEQADAVLFGSVGGP 79
>LEU3_SHIDS (Q32K21) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 32.0 bits (71), Expect = 0.91 Identities = 22/75 (29%), Positives = 32/75 (42%), Gaps = 11/75 (14%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVMEAM-----------HAPVYFETYDVHGDMPAVPPAVIES 380 + +PGDGIGP V +V++A+ H V D HG +PPA +E Sbjct: 7 IAALPGDGIGPEVMTQALKVLDAVRNRFAMRITTSHYDVGGAAIDNHGQ--PLPPATVEG 64 Query: 381 IPRNKVCLKGGLATP 425 + L G + P Sbjct: 65 CEQADAVLFGSVGGP 79
>MYO15_HUMAN (Q9UKN7) Myosin-15 (Myosin XV) (Unconventional myosin-15)| Length = 3530 Score = 32.0 bits (71), Expect = 0.91 Identities = 15/37 (40%), Positives = 21/37 (56%) Frame = -3 Query: 277 PVTRGPMPSPGMSVTGRGVPSPGRGM*VTVRRAPPPW 167 P + GP P+P +S G+P P ++RR PPPW Sbjct: 669 PPSSGPPPAPPLSPALSGLPRPASPY-GSLRRHPPPW 704
>LEU3_PSEHT (Q3IJS3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 358 Score = 32.0 bits (71), Expect = 0.91 Identities = 21/75 (28%), Positives = 33/75 (44%), Gaps = 11/75 (14%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVMEAM-----------HAPVYFETYDVHGDMPAVPPAVIES 380 V ++ GDGIGP + A EQV++A+ H + D HG A+P + + + Sbjct: 8 VAVLAGDGIGPEIMAAAEQVLDAVSNKFGFTLNREHHAIGGAAIDKHG--KALPQSTVTA 65 Query: 381 IPRNKVCLKGGLATP 425 L G + P Sbjct: 66 CENADAILFGAVGGP 80
>LEU3_SHIFL (Q83SP1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 362 Score = 32.0 bits (71), Expect = 0.91 Identities = 22/75 (29%), Positives = 32/75 (42%), Gaps = 11/75 (14%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVMEAM-----------HAPVYFETYDVHGDMPAVPPAVIES 380 + ++PGDGIGP V +V+ A+ H V D HG +PPA +E Sbjct: 6 IAVLPGDGIGPEVMTQALKVLNAVRNRFAMRITTSHYDVGGAAIDNHGQ--PLPPATVEG 63 Query: 381 IPRNKVCLKGGLATP 425 + L G + P Sbjct: 64 CEQADAVLFGSVGGP 78
>IDH_STRMU (Q59940) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 393 Score = 31.6 bits (70), Expect = 1.2 Identities = 23/83 (27%), Positives = 37/83 (44%), Gaps = 14/83 (16%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYF--------------ETYDVHGDMPAVPPAV 371 + I GDG+G + + V + A VY + Y+ G+ +P Sbjct: 20 IPYIEGDGVGQDIWKNAQIVFDKAIAKVYGGHKQVIWREVLAGKKAYNETGNW--LPNET 77 Query: 372 IESIPRNKVCLKGGLATPVGGGV 440 +E I + + +KG L TPVGGG+ Sbjct: 78 LEIIKTHLLAIKGPLETPVGGGI 100
>LEU3_MYCLE (O33117) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 336 Score = 31.6 bits (70), Expect = 1.2 Identities = 18/69 (26%), Positives = 32/69 (46%), Gaps = 5/69 (7%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDV-----HGDMPAVPPAVIESIPRNKV 398 + +I GDGIGP V ++++ + V TYD+ H +P +V+ + + Sbjct: 3 LAIIGGDGIGPEVVAQAVKILDVVLPGVQKTTYDLGARRYHTTGELLPESVLAELREHDA 62 Query: 399 CLKGGLATP 425 L G + P Sbjct: 63 ILLGAVGDP 71
>LEU3_PHACH (O59930) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 380 Score = 31.6 bits (70), Expect = 1.2 Identities = 23/77 (29%), Positives = 34/77 (44%), Gaps = 10/77 (12%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHA-----PVYFETYDVHG---DMPAVP--PAVIESI 383 + ++PGDGIGP V +V+E + A + ET+D G D P A +E+ Sbjct: 8 IVILPGDGIGPEVVAEATRVLEVVSASSSDVEIKLETHDFGGCSIDKHGEPLTAATLEAC 67 Query: 384 PRNKVCLKGGLATPVGG 434 L G + P G Sbjct: 68 KLADAILLGAIGGPKWG 84
>LEU3_BACHD (Q9K8E9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 31.6 bits (70), Expect = 1.2 Identities = 12/26 (46%), Positives = 20/26 (76%) Frame = +3 Query: 228 RPVTLIPGDGIGPLVTGAVEQVMEAM 305 + + ++PGDGIGP VT A +V++A+ Sbjct: 3 KQIAVLPGDGIGPEVTDAAIEVLQAV 28
>LEU3_THEFY (Q47SB4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 354 Score = 31.6 bits (70), Expect = 1.2 Identities = 23/74 (31%), Positives = 34/74 (45%), Gaps = 10/74 (13%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDV----------HGDMPAVPPAVIESI 383 + +IPGDGIGP V +V+ A+ AP + T D H +P AV E + Sbjct: 8 LAVIPGDGIGPEVVAEGLKVLSAV-APRHGLTLDTTEYELGAQRWHATGEVLPDAVEEEL 66 Query: 384 PRNKVCLKGGLATP 425 ++ L G + P Sbjct: 67 RQHDAILLGAVGDP 80
>LEU3_SALTY (P37412) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 31.2 bits (69), Expect = 1.6 Identities = 19/73 (26%), Positives = 31/73 (42%), Gaps = 9/73 (12%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHGDMPAV---------PPAVIESIP 386 + ++PGDGIGP V +VM+A+ + H D+ + P A +E Sbjct: 7 IAVLPGDGIGPEVMAQALKVMDAVRSRFDMRITTSHYDVGGIAIDNHGHPLPKATVEGCE 66 Query: 387 RNKVCLKGGLATP 425 + L G + P Sbjct: 67 QADAILFGSVGGP 79
>LEU3_SALCH (Q57TE7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 31.2 bits (69), Expect = 1.6 Identities = 19/73 (26%), Positives = 31/73 (42%), Gaps = 9/73 (12%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHGDMPAV---------PPAVIESIP 386 + ++PGDGIGP V +VM+A+ + H D+ + P A +E Sbjct: 7 IAVLPGDGIGPEVMAQALKVMDAVRSRFDMRITTSHYDVGGIAIDNHGHPLPKATVEGCE 66 Query: 387 RNKVCLKGGLATP 425 + L G + P Sbjct: 67 QADAILFGSVGGP 79
>LEU3_ACIAD (Q6FEV6) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 359 Score = 31.2 bits (69), Expect = 1.6 Identities = 20/77 (25%), Positives = 31/77 (40%), Gaps = 11/77 (14%) Frame = +3 Query: 228 RPVTLIPGDGIGPLVTGAVEQVMEAM-----------HAPVYFETYDVHGDMPAVPPAVI 374 + + ++ GDGIGP + GA EQV+ + H + D HG+ P Sbjct: 3 KQILILAGDGIGPEIVGAAEQVLTKVNEKFELGLTWEHGLLGGSAIDAHGE--PYPAVTS 60 Query: 375 ESIPRNKVCLKGGLATP 425 E + L G + P Sbjct: 61 EQAKKADAILLGAVGGP 77
>KDSB_VIBCH (Q9KQX2) 3-deoxy-manno-octulosonate cytidylyltransferase (EC| 2.7.7.38) (CMP-KDO synthetase) (CMP-2-keto-3-deoxyoctulosonic acid synthetase) (CKS) Length = 252 Score = 31.2 bits (69), Expect = 1.6 Identities = 15/50 (30%), Positives = 23/50 (46%) Frame = +3 Query: 273 TGAVEQVMEAMHAPVYFETYDVHGDMPAVPPAVIESIPRNKVCLKGGLAT 422 T + +V+ M P +V GD P +PPA+I + N +AT Sbjct: 76 TERLAEVVAKMAIPADHIVVNVQGDEPLIPPAIIRQVADNLAACSAPMAT 125
>WASP_MOUSE (P70315) Wiskott-Aldrich syndrome protein homolog (WASp)| Length = 520 Score = 31.2 bits (69), Expect = 1.6 Identities = 32/103 (31%), Positives = 37/103 (35%) Frame = -3 Query: 460 ELHVREETPPPTGVARPPLRQTLLRGMDSMTAGGTAGMSPWTSYVSK*TGACMASMTCST 281 E+ +E PPP PP R G GG G P V + S + Sbjct: 308 EMRRQEPLPPPP----PPCRGGGGGGGGGGGGGGGGGGQPLRPPV-------VGSNKGRS 356 Query: 280 APVTRGPMPSPGMSVTGRGVPSPGRGM*VTVRRAPPPWPGRDG 152 P+ PM T RG P PGRG PPP GR G Sbjct: 357 GPLPPVPMGGAPPPPTPRGPPPPGRG---GPPPPPPPATGRSG 396
>LEU3_BRUSU (Q8FVF3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 370 Score = 31.2 bits (69), Expect = 1.6 Identities = 24/77 (31%), Positives = 35/77 (45%), Gaps = 11/77 (14%) Frame = +3 Query: 228 RPVTLIPGDGIGPLVTGAVEQVMEAMHAPVY--FET---------YDVHGDMPAVPPAVI 374 R + L+PGDGIGP V +V+ +++ + FET YD HG A+ A + Sbjct: 4 RKLLLLPGDGIGPEAMAEVRKVIAFLNSDLNLGFETEEGLVGGCAYDAHGQ--AISDADM 61 Query: 375 ESIPRNKVCLKGGLATP 425 E L G + P Sbjct: 62 EKALAADAVLFGAVGGP 78
>LEU3_BRUME (Q8YCX4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 370 Score = 31.2 bits (69), Expect = 1.6 Identities = 24/77 (31%), Positives = 35/77 (45%), Gaps = 11/77 (14%) Frame = +3 Query: 228 RPVTLIPGDGIGPLVTGAVEQVMEAMHAPVY--FET---------YDVHGDMPAVPPAVI 374 R + L+PGDGIGP V +V+ +++ + FET YD HG A+ A + Sbjct: 4 RKLLLLPGDGIGPEAMAEVRKVIAFLNSDLNLGFETEEGLVGGCAYDAHGQ--AISDADM 61 Query: 375 ESIPRNKVCLKGGLATP 425 E L G + P Sbjct: 62 EKALAADAVLFGAVGGP 78
>KDSB_VIBPA (Q87R14) 3-deoxy-manno-octulosonate cytidylyltransferase (EC| 2.7.7.38) (CMP-KDO synthetase) (CMP-2-keto-3-deoxyoctulosonic acid synthetase) (CKS) Length = 251 Score = 31.2 bits (69), Expect = 1.6 Identities = 16/50 (32%), Positives = 23/50 (46%) Frame = +3 Query: 273 TGAVEQVMEAMHAPVYFETYDVHGDMPAVPPAVIESIPRNKVCLKGGLAT 422 T + +V+E M P +V GD P VPP +I + N +AT Sbjct: 76 TERLAEVVEKMAIPADHIIVNVQGDEPLVPPVIIRQVADNLAASDAPMAT 125
>LEU3_THEAQ (P24098) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 344 Score = 30.8 bits (68), Expect = 2.0 Identities = 13/24 (54%), Positives = 19/24 (79%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVMEAM 305 V ++PGDGIGP VT A +V++A+ Sbjct: 3 VAVLPGDGIGPEVTEAALRVLKAL 26
>LEU3_SALTI (Q8Z9I1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 30.8 bits (68), Expect = 2.0 Identities = 21/73 (28%), Positives = 33/73 (45%), Gaps = 9/73 (12%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHA----PVYFETYDVHG-----DMPAVPPAVIESIP 386 + ++PGDGIGP V +VM+A+ + + YDV G +P A +E Sbjct: 7 IAVLPGDGIGPEVMAQALKVMDAVRSRFDMRITTSRYDVGGIAIDNHGHPLPKATVEGCE 66 Query: 387 RNKVCLKGGLATP 425 + L G + P Sbjct: 67 QADAILFGSVGGP 79
>LEU3_SALPA (Q5PDG2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 30.8 bits (68), Expect = 2.0 Identities = 21/73 (28%), Positives = 33/73 (45%), Gaps = 9/73 (12%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHA----PVYFETYDVHG-----DMPAVPPAVIESIP 386 + ++PGDGIGP V +VM+A+ + + YDV G +P A +E Sbjct: 7 IAVLPGDGIGPEVMAQALKVMDAVRSRFDMRITTSRYDVGGIAIDNHGHPLPKATVEGCE 66 Query: 387 RNKVCLKGGLATP 425 + L G + P Sbjct: 67 QADAILFGSVGGP 79
>NMDE3_HUMAN (Q14957) Glutamate [NMDA] receptor subunit epsilon 3 precursor| (N-methyl D-aspartate receptor subtype 2C) (NR2C) (NMDAR2C) Length = 1233 Score = 30.8 bits (68), Expect = 2.0 Identities = 20/41 (48%), Positives = 21/41 (51%) Frame = -3 Query: 280 APVTRGPMPSPGMSVTGRGVPSPGRGM*VTVRRAPPPWPGR 158 +P P P P S TG G P GR VRRAP P PGR Sbjct: 943 SPCLPTPDPPPEPSPTGWGPPDGGRA--ALVRRAPQP-PGR 980
>LEU3_THETH (P61495) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 345 Score = 30.4 bits (67), Expect = 2.7 Identities = 13/24 (54%), Positives = 18/24 (75%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVMEAM 305 V ++PGDGIGP VT A +V+ A+ Sbjct: 3 VAVLPGDGIGPEVTEAALKVLRAL 26
>LEU3_THET8 (Q5SIY4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 345 Score = 30.4 bits (67), Expect = 2.7 Identities = 13/24 (54%), Positives = 18/24 (75%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVMEAM 305 V ++PGDGIGP VT A +V+ A+ Sbjct: 3 VAVLPGDGIGPEVTEAALKVLRAL 26
>LEU3_THET2 (P61494) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 345 Score = 30.4 bits (67), Expect = 2.7 Identities = 13/24 (54%), Positives = 18/24 (75%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVMEAM 305 V ++PGDGIGP VT A +V+ A+ Sbjct: 3 VAVLPGDGIGPEVTEAALKVLRAL 26
>LEU3_PROMM (Q7V842) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 357 Score = 30.4 bits (67), Expect = 2.7 Identities = 18/73 (24%), Positives = 36/73 (49%), Gaps = 9/73 (12%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVMEAM---HA-PVYFETYDVHG-----DMPAVPPAVIESIP 386 + L+PGDGIGP +T + +++A+ H + FE + + G +P + +E+ Sbjct: 6 IVLLPGDGIGPEITAVAKLLLDALGHQHGFKLNFEQHPIGGVAIDASGSPLPASTLEACQ 65 Query: 387 RNKVCLKGGLATP 425 + L + +P Sbjct: 66 ASDAVLLAAIGSP 78
>SPN90_HUMAN (Q9NZQ3) SH3 adapter protein SPIN90 (NCK-interacting protein with| SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (AF3p21) (Diaphanous protein-interacting protein) (Dia-interacting protein 1) Length = 722 Score = 30.4 bits (67), Expect = 2.7 Identities = 24/90 (26%), Positives = 36/90 (40%) Frame = -3 Query: 439 TPPPTGVARPPLRQTLLRGMDSMTAGGTAGMSPWTSYVSK*TGACMASMTCSTAPVTRGP 260 TPPP P+++ R +++ A G+ G + S + + S T T Sbjct: 181 TPPP------PVKR---RDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDTLYTSSS 231 Query: 259 MPSPGMSVTGRGVPSPGRGM*VTVRRAPPP 170 PG S + P P RG TV + PP Sbjct: 232 PSEPGSSCSPTPPPVPRRGTHTTVSQVQPP 261
>LEU3_RALEJ (Q46YW0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 355 Score = 30.4 bits (67), Expect = 2.7 Identities = 13/37 (35%), Positives = 20/37 (54%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHG 344 + ++PGDGIGP + +V+ A+ ET V G Sbjct: 3 IAVLPGDGIGPEIVAEAVKVLNALDEKFEMETAPVGG 39
>LEU3_AZOSE (Q5P1J6) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 350 Score = 30.4 bits (67), Expect = 2.7 Identities = 11/24 (45%), Positives = 18/24 (75%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVMEAM 305 + ++PGDGIGP +T +V+EA+ Sbjct: 3 ICILPGDGIGPEITAEAVRVIEAL 26
>TTUC5_AGRVI (O34295) Probable tartrate dehydrogenase/decarboxylase ttuC' (EC| 1.1.1.93) (EC 4.1.1.73) (TDH) (D-malate dehydrogenase [decarboxylating]) (EC 1.1.1.83) Length = 358 Score = 30.4 bits (67), Expect = 2.7 Identities = 17/43 (39%), Positives = 23/43 (53%), Gaps = 5/43 (11%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHA-----PVYFETYDVHGD 347 + IP DGIGP V A QV+EA+ ++ ET+D D Sbjct: 6 IAAIPADGIGPEVIAAGLQVLEALEQRSGDFKIHTETFDWGSD 48
>TTUC4_AGRVI (P70792) Probable tartrate dehydrogenase/decarboxylase ttuC' (EC| 1.1.1.93) (EC 4.1.1.73) (TDH) (D-malate dehydrogenase [decarboxylating]) (EC 1.1.1.83) Length = 358 Score = 30.4 bits (67), Expect = 2.7 Identities = 17/43 (39%), Positives = 23/43 (53%), Gaps = 5/43 (11%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHA-----PVYFETYDVHGD 347 + IP DGIGP V A QV+EA+ ++ ET+D D Sbjct: 6 IAAIPADGIGPEVIAAGLQVLEALEKRSGDFSIHTETFDWGSD 48
>TTUC3_AGRVI (O34296) Probable tartrate dehydrogenase/decarboxylase ttuC' (EC| 1.1.1.93) (EC 4.1.1.73) (TDH) (D-malate dehydrogenase [decarboxylating]) (EC 1.1.1.83) Length = 358 Score = 30.4 bits (67), Expect = 2.7 Identities = 17/43 (39%), Positives = 23/43 (53%), Gaps = 5/43 (11%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHA-----PVYFETYDVHGD 347 + IP DGIGP V A QV+EA+ ++ ET+D D Sbjct: 6 IAAIPADGIGPEVIAAGLQVLEALEQRSGDFKIHTETFDWGSD 48
>TTUC2_AGRVI (P70787) Probable tartrate dehydrogenase/decarboxylase ttuC (EC| 1.1.1.93) (EC 4.1.1.73) (TDH) (D-malate dehydrogenase [decarboxylating]) (EC 1.1.1.83) Length = 364 Score = 30.4 bits (67), Expect = 2.7 Identities = 17/43 (39%), Positives = 23/43 (53%), Gaps = 5/43 (11%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHA-----PVYFETYDVHGD 347 + IP DGIGP V A QV+EA+ ++ ET+D D Sbjct: 6 IAAIPADGIGPEVIAAGLQVLEALEKRSGDFSIHTETFDWGSD 48
>TTUC1_AGRVI (Q44471) Probable tartrate dehydrogenase/decarboxylase ttuC (EC| 1.1.1.93) (EC 4.1.1.73) (TDH) (D-malate dehydrogenase [decarboxylating]) (EC 1.1.1.83) Length = 364 Score = 30.4 bits (67), Expect = 2.7 Identities = 17/43 (39%), Positives = 23/43 (53%), Gaps = 5/43 (11%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHA-----PVYFETYDVHGD 347 + IP DGIGP V A QV+EA+ ++ ET+D D Sbjct: 6 IAAIPADGIGPEVIAAGLQVLEALEQRSGDFKIHTETFDWGSD 48
>LEU3_BACSK (Q5WEN4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 364 Score = 30.4 bits (67), Expect = 2.7 Identities = 13/35 (37%), Positives = 23/35 (65%) Frame = +3 Query: 228 RPVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETY 332 + + L+PGDGIGP + ++V+E + A +Y T+ Sbjct: 3 KQILLLPGDGIGPEIIAETKRVLEEI-ARLYHHTF 36
>IDH3B_PIG (P56472) Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial| (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) (Fragments) Length = 103 Score = 30.0 bits (66), Expect = 3.5 Identities = 11/18 (61%), Positives = 15/18 (83%) Frame = +3 Query: 231 PVTLIPGDGIGPLVTGAV 284 PVT++PGDG+GP + AV Sbjct: 16 PVTMLPGDGVGPELMAAV 33
>FBX41_HUMAN (Q8TF61) F-box only protein 41| Length = 874 Score = 30.0 bits (66), Expect = 3.5 Identities = 14/31 (45%), Positives = 16/31 (51%) Frame = -3 Query: 304 MASMTCSTAPVTRGPMPSPGMSVTGRGVPSP 212 +AS CST P GP P PG + PSP Sbjct: 162 VASSACSTPPPGPGPGPCPGPASASPASPSP 192
>CSKI1_HUMAN (Q8WXD9) Caskin-1 (CASK-interacting protein 1)| Length = 1431 Score = 30.0 bits (66), Expect = 3.5 Identities = 29/104 (27%), Positives = 36/104 (34%), Gaps = 9/104 (8%) Frame = -3 Query: 448 REETPPPTGVARPPLRQTLLRGMDSMTAGGTAGMSPWTSYVS------K*TGACMASMTC 287 R+ PP T PP T R GG G +P T+ V T M+ + Sbjct: 764 RQVLPPGTSHFTPPQTPTKTRPGSPQALGGPHGPAPATAKVKPTPQLLPPTERPMSPRSL 823 Query: 286 STAPVTRG---PMPSPGMSVTGRGVPSPGRGM*VTVRRAPPPWP 164 +P RG +P P G P P APPP P Sbjct: 824 PQSPTHRGFAYVLPQPVEGEVGPAAPGP----------APPPVP 857
>SENP3_HUMAN (Q9H4L4) Sentrin-specific protease 3 (EC 3.4.22.-)| (Sentrin/SUMO-specific protease SENP3) (SUMO-1-specific protease 3) Length = 574 Score = 30.0 bits (66), Expect = 3.5 Identities = 15/38 (39%), Positives = 17/38 (44%) Frame = -3 Query: 262 PMPSPGMSVTGRGVPSPGRGM*VTVRRAPPPWPGRDGA 149 P P P + G P PG G V RR P P P D + Sbjct: 36 PPPKPRLKSGGGFGPDPGSGTTVPTRRLPAPRPSFDAS 73
>LEU3_RHIME (Q92KY8) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 370 Score = 30.0 bits (66), Expect = 3.5 Identities = 18/52 (34%), Positives = 24/52 (46%), Gaps = 11/52 (21%) Frame = +3 Query: 222 TPRPVTLIPGDGIGPLVTGAVEQVMEAMHAP-----------VYFETYDVHG 344 T R + L+PGDGIGP V +++ M+A V YD HG Sbjct: 2 TVRNLFLLPGDGIGPEAMAEVRKIIAYMNAERDAGFVTDEGLVGGSAYDAHG 53
>LEU3_CAUCR (Q9ABN3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 350 Score = 30.0 bits (66), Expect = 3.5 Identities = 16/42 (38%), Positives = 22/42 (52%), Gaps = 7/42 (16%) Frame = +3 Query: 240 LIPGDGIGPLVTGAVEQVMEAMHAPVYFE-------TYDVHG 344 L+PGDGIGP V V +V A+ + + +YD HG Sbjct: 6 LLPGDGIGPEVCAQVRRVAAALTPDLKVDEALYGGASYDTHG 47
>Y1617_METMA (Q8PWH0) UPF0272 protein MM1617| Length = 396 Score = 30.0 bits (66), Expect = 3.5 Identities = 14/39 (35%), Positives = 20/39 (51%), Gaps = 5/39 (12%) Frame = +3 Query: 339 HGDMPAVPPAVIESIPRNKVCLKGG-----LATPVGGGV 440 HG +P PA +E + R K+ +GG L TP G + Sbjct: 159 HGTLPVPAPATLEILRRGKLYFRGGNVNKELLTPTGAAI 197
>KDSB_YERPE (Q8ZGA4) 3-deoxy-manno-octulosonate cytidylyltransferase (EC| 2.7.7.38) (CMP-KDO synthetase) (CMP-2-keto-3-deoxyoctulosonic acid synthetase) (CKS) Length = 250 Score = 30.0 bits (66), Expect = 3.5 Identities = 12/30 (40%), Positives = 16/30 (53%) Frame = +3 Query: 333 DVHGDMPAVPPAVIESIPRNKVCLKGGLAT 422 +V GD P VPP +I + N G+AT Sbjct: 96 NVQGDEPLVPPVIIRQVADNLAACSAGMAT 125
>LEU31_ARATH (Q9SA14) 3-isopropylmalate dehydrogenase 1, chloroplast precursor| (EC 1.1.1.85) (Beta-IPM dehydrogenase 1) (IMDH 1) (3-IPM-DH 1) Length = 406 Score = 29.6 bits (65), Expect = 4.5 Identities = 11/22 (50%), Positives = 16/22 (72%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVME 299 +TL+PGDGIGP V + V++ Sbjct: 46 ITLLPGDGIGPEVISVAKNVLQ 67
>LEU3_VIBVY (Q7MP78) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 29.6 bits (65), Expect = 4.5 Identities = 17/42 (40%), Positives = 27/42 (64%), Gaps = 5/42 (11%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVMEAM---HAPVYF--ETYDVHG 344 + ++PGDGIGP V +V++A+ HA ++F E +DV G Sbjct: 8 IAVLPGDGIGPEVMAQAHKVLDAIEKKHA-IHFEREEHDVGG 48
>LEU3_VIBVU (Q8DEE0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 29.6 bits (65), Expect = 4.5 Identities = 17/42 (40%), Positives = 27/42 (64%), Gaps = 5/42 (11%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVMEAM---HAPVYF--ETYDVHG 344 + ++PGDGIGP V +V++A+ HA ++F E +DV G Sbjct: 8 IAVLPGDGIGPEVMAQAHKVLDAIEKKHA-IHFEREEHDVGG 48
>LEU3_BRAJA (Q89X19) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 370 Score = 29.6 bits (65), Expect = 4.5 Identities = 17/45 (37%), Positives = 26/45 (57%), Gaps = 11/45 (24%) Frame = +3 Query: 240 LIPGDGIGPLVTGAVEQVMEAMHAP--VYFET---------YDVH 341 L+PGDGIGP V G V+++++ +++ FET YD H Sbjct: 8 LLPGDGIGPEVMGEVKRLIDWLNSAGIAKFETDTGLVGGSAYDAH 52
>LEU32_ARATH (P93832) 3-isopropylmalate dehydrogenase 2, chloroplast precursor| (EC 1.1.1.85) (Beta-IPM dehydrogenase 2) (IMDH 2) (3-IPM-DH 2) Length = 405 Score = 29.6 bits (65), Expect = 4.5 Identities = 11/22 (50%), Positives = 16/22 (72%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVME 299 +TL+PGDGIGP V + V++ Sbjct: 45 ITLLPGDGIGPEVVSIAKNVLQ 66
>CENG1_HUMAN (Q99490) Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like,| ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase activating protein 2) (GGAP2) Length = 1192 Score = 29.6 bits (65), Expect = 4.5 Identities = 16/42 (38%), Positives = 20/42 (47%) Frame = -3 Query: 286 STAPVTRGPMPSPGMSVTGRGVPSPGRGM*VTVRRAPPPWPG 161 S P+T P PSP +VT PG +T+ PP PG Sbjct: 289 SPPPLTLPPTPSPATAVTAASAQPPGPAPPITLE---PPAPG 327
>LEU3_METCA (Q606F4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 360 Score = 29.6 bits (65), Expect = 4.5 Identities = 14/48 (29%), Positives = 23/48 (47%), Gaps = 11/48 (22%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVMEAM-----------HAPVYFETYDVHG 344 + ++PGDGIGP + +V++ + HA + YD HG Sbjct: 5 IAVLPGDGIGPEIVAEALKVLDCLRSDFGLAVETEHALIGGAAYDAHG 52
>LEU3_BRANA (P29102) 3-isopropylmalate dehydrogenase, chloroplast precursor (EC| 1.1.1.85) (Beta-IPM dehydrogenase) (IMDH) (3-IPM-DH) Length = 406 Score = 29.3 bits (64), Expect = 5.9 Identities = 11/22 (50%), Positives = 16/22 (72%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVME 299 +TL+PGDGIGP V + V++ Sbjct: 46 ITLLPGDGIGPEVISIAKNVLQ 67
>LEU3_YERPS (Q66EM2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 29.3 bits (64), Expect = 5.9 Identities = 14/41 (34%), Positives = 22/41 (53%), Gaps = 4/41 (9%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMH----APVYFETYDVHG 344 + ++PGDGIGP V +V++A+ + YDV G Sbjct: 7 IAVLPGDGIGPEVMAQASKVLDAVRQRFGLKISTSVYDVGG 47
>LEU3_YERPE (Q8ZIG9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 29.3 bits (64), Expect = 5.9 Identities = 14/41 (34%), Positives = 22/41 (53%), Gaps = 4/41 (9%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMH----APVYFETYDVHG 344 + ++PGDGIGP V +V++A+ + YDV G Sbjct: 7 IAVLPGDGIGPEVMAQASKVLDAVRQRFGLKISTSVYDVGG 47
>HSLU_AQUAE (O66574) ATP-dependent hsl protease ATP-binding subunit hslU| Length = 450 Score = 29.3 bits (64), Expect = 5.9 Identities = 14/41 (34%), Positives = 23/41 (56%) Frame = -3 Query: 484 GEEVELLAELHVREETPPPTGVARPPLRQTLLRGMDSMTAG 362 GE + + E+ V+E+T P G+A PP + L + M +G Sbjct: 173 GELDDRIVEIEVKEKTVPMVGIAGPPGLEELENQIKEMLSG 213
>MUCDL_RAT (Q9JIK1) Mucin and cadherin-like protein precursor| (Mu-protocadherin) (GP100) Length = 862 Score = 29.3 bits (64), Expect = 5.9 Identities = 20/78 (25%), Positives = 31/78 (39%) Frame = -3 Query: 466 LAELHVREETPPPTGVARPPLRQTLLRGMDSMTAGGTAGMSPWTSYVSK*TGACMASMTC 287 + E+ V E PP T PP AGGT G S T+ + T Sbjct: 449 IVEIQVSEREPPSTESPTPP------------EAGGTTGPSSNTTLETPSTSGTSQGPAT 496 Query: 286 STAPVTRGPMPSPGMSVT 233 +++ + GP P G +++ Sbjct: 497 TSSGGSAGPFPPAGTTLS 514
>MUC2_RAT (Q62635) Mucin-2 precursor (Intestinal mucin 2) (Fragment)| Length = 1513 Score = 29.3 bits (64), Expect = 5.9 Identities = 23/78 (29%), Positives = 33/78 (42%), Gaps = 2/78 (2%) Frame = -3 Query: 439 TPPPTGVARPPLRQTLLRGMDSMTAGGTAGMSPWTSYVSK*TGACMASMTCSTAPV--TR 266 T P T A P + + T+ T+ SP TS + T ++ + + +P T Sbjct: 1415 TSPLTSSATSPTTSHITSTVSPTTSPTTSTTSPTTSPTTSTTSPTTSTTSPTPSPTTSTT 1474 Query: 265 GPMPSPGMSVTGRGVPSP 212 P PSP S T PSP Sbjct: 1475 SPTPSPTTSTTS-PTPSP 1491
>LEU3_PELCD (Q3A3B2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 365 Score = 29.3 bits (64), Expect = 5.9 Identities = 20/73 (27%), Positives = 33/73 (45%), Gaps = 9/73 (12%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHA--PVYFETY-------DVHGDMPAVPPAVIESIP 386 + ++PGDGIGP + +V++A+ V FE + D A+P A +E Sbjct: 7 LAVLPGDGIGPEIMAEAMKVLDAVEQKFQVRFERQFANVGGAAIDRDGKALPDATVEICQ 66 Query: 387 RNKVCLKGGLATP 425 + L G + P Sbjct: 67 ASDAILFGSVGGP 79
>EFS_MOUSE (Q64355) Embryonal Fyn-associated substrate (SRC-interacting| protein) (Signal-integrating protein) Length = 560 Score = 28.9 bits (63), Expect = 7.7 Identities = 16/38 (42%), Positives = 19/38 (50%) Frame = -3 Query: 277 PVTRGPMPSPGMSVTGRGVPSPGRGM*VTVRRAPPPWP 164 PV+ P PSP S P+PGR + R PPP P Sbjct: 310 PVSEAPAPSPAPS------PAPGRKGSIQDRPLPPPPP 341
>BAG3_MOUSE (Q9JLV1) BAG family molecular chaperone regulator 3 (BCL-2-binding| athanogene-3) (BAG-3) (Bcl-2-binding protein Bis) Length = 577 Score = 28.9 bits (63), Expect = 7.7 Identities = 14/42 (33%), Positives = 19/42 (45%) Frame = -3 Query: 274 VTRGPMPSPGMSVTGRGVPSPGRGM*VTVRRAPPPWPGRDGA 149 V+ P+P P S VPSP + + + AP P P A Sbjct: 371 VSSAPIPCPSPSPAPSAVPSPPKNVAAEQKAAPSPAPAEPAA 412
>MUC2_HUMAN (Q02817) Mucin-2 precursor (Intestinal mucin 2)| Length = 5179 Score = 28.9 bits (63), Expect = 7.7 Identities = 24/90 (26%), Positives = 33/90 (36%) Frame = -3 Query: 439 TPPPTGVARPPLRQTLLRGMDSMTAGGTAGMSPWTSYVSK*TGACMASMTCSTAPVTRGP 260 TPPPT PP+ + + T T SP T+ T +T P T P Sbjct: 1493 TPPPTTTPSPPMTTPITPPASTTTLPPTTTPSPPTT-------------TTTTPPPTTTP 1539 Query: 259 MPSPGMSVTGRGVPSPGRGM*VTVRRAPPP 170 P +T P+ + T +PPP Sbjct: 1540 SPPTTTPIT---PPTSTTTLPPTTTPSPPP 1566
>Y429_METAC (Q8TTK2) UPF0272 protein MA0429| Length = 396 Score = 28.9 bits (63), Expect = 7.7 Identities = 13/39 (33%), Positives = 20/39 (51%), Gaps = 5/39 (12%) Frame = +3 Query: 339 HGDMPAVPPAVIESIPRNKVCLKGG-----LATPVGGGV 440 HG +P PA +E + + K+ +GG L TP G + Sbjct: 159 HGTLPVPAPATLEILRKGKLYFRGGSVNKELLTPTGAAI 197
>LEU3_GEOSL (Q748X2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 362 Score = 28.9 bits (63), Expect = 7.7 Identities = 12/26 (46%), Positives = 18/26 (69%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHA 311 V ++PGDGIGP V +V++A+ A Sbjct: 7 VAVLPGDGIGPEVMAEALRVLDAVEA 32
>UCRI_PROMM (Q7V654) Cytochrome b6-f complex iron-sulfur subunit (EC 1.10.99.1)| (Rieske iron-sulfur protein) (Plastohydroquinone:plastocyanin oxidoreductase iron-sulfur protein) (ISP) (RISP) Length = 178 Score = 28.9 bits (63), Expect = 7.7 Identities = 14/30 (46%), Positives = 15/30 (50%) Frame = -3 Query: 343 PWTSYVSK*TGACMASMTCSTAPVTRGPMP 254 PW S V+K C S ST V RGP P Sbjct: 115 PWNSGVNKFVCPCHGSQYNSTGKVVRGPAP 144
>SF3A2_HUMAN (Q15428) Splicing factor 3A subunit 2 (Spliceosome-associated| protein 62) (SAP 62) (SF3a66) Length = 464 Score = 28.9 bits (63), Expect = 7.7 Identities = 22/59 (37%), Positives = 25/59 (42%), Gaps = 4/59 (6%) Frame = +3 Query: 204 PRPGDGTPRPVTLIPGDGIGPLVTGAVEQVMEAMHAP---VYFETYDVHGDMPAV-PPA 368 P PG P PV P G+ P G V +H P V+ T VH P V PPA Sbjct: 283 PAPGVHPPAPVVHPPASGVHPPAPG-VHPPAPGVHPPAPGVHPPTSGVHPPAPGVHPPA 340
>LEU3_CORDI (Q6NHM7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 339 Score = 28.9 bits (63), Expect = 7.7 Identities = 20/71 (28%), Positives = 34/71 (47%), Gaps = 7/71 (9%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDV-------HGDMPAVPPAVIESIPRN 392 + +I GDGIGP VT +V+ A+ + YD+ +G++ A A + S+ + Sbjct: 3 LAVIGGDGIGPEVTAEALKVLNAVRDDIEVTDYDLGARRYLRNGELLA--DADLVSLREH 60 Query: 393 KVCLKGGLATP 425 L G + P Sbjct: 61 DAILLGAIGAP 71
>LEU3_SYNP6 (Q5MZ40) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 365 Score = 28.9 bits (63), Expect = 7.7 Identities = 10/24 (41%), Positives = 16/24 (66%) Frame = +3 Query: 234 VTLIPGDGIGPLVTGAVEQVMEAM 305 +TL+PGDGIGP + ++ A+ Sbjct: 7 ITLLPGDGIGPEIMAVTVDILRAI 30
>LEU3_SILPO (Q5LWZ5) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 367 Score = 26.2 bits (56), Expect(2) = 9.9 Identities = 15/46 (32%), Positives = 21/46 (45%), Gaps = 11/46 (23%) Frame = +3 Query: 240 LIPGDGIGPLVTGAVEQVM-----------EAMHAPVYFETYDVHG 344 ++PGDGIGP V V +++ + V YDVHG Sbjct: 8 ILPGDGIGPEVMAEVRKIIGWFGDKRGLNFDVSEDLVGGAAYDVHG 53 Score = 20.8 bits (42), Expect(2) = 9.9 Identities = 7/12 (58%), Positives = 12/12 (100%) Frame = +2 Query: 452 MQLRKELDLFAS 487 ++LRKE+DLF++ Sbjct: 94 LRLRKEMDLFSN 105 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 41,643,659 Number of Sequences: 219361 Number of extensions: 856272 Number of successful extensions: 4533 Number of sequences better than 10.0: 139 Number of HSP's better than 10.0 without gapping: 4105 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4456 length of database: 80,573,946 effective HSP length: 103 effective length of database: 57,979,763 effective search space used: 3420806017 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)