ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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更新日:2016年5月1日

Clone Information

BLAST Search Result

Clone Name bart59g08
Clone Library Name barley_pub

No. Definition Score
(bits)
E
Value
1IDH3A_CAEEL (Q93714) Probable isocitrate dehydrogenase [NAD] sub... 65 1e-10
2IDH3A_DROME (Q9VWH4) Probable isocitrate dehydrogenase [NAD] sub... 63 4e-10
3IDH3A_BOVIN (P41563) Isocitrate dehydrogenase [NAD] subunit alph... 62 6e-10
4IDH3A_RAT (Q99NA5) Isocitrate dehydrogenase [NAD] subunit alpha,... 62 1e-09
5IDH3A_MOUSE (Q9D6R2) Isocitrate dehydrogenase [NAD] subunit alph... 62 1e-09
6IDH2_YEAST (P28241) Isocitrate dehydrogenase [NAD] subunit 2, mi... 60 4e-09
7IDH3A_PONPY (Q5R678) Isocitrate dehydrogenase [NAD] subunit alph... 59 5e-09
8IDH3A_HUMAN (P50213) Isocitrate dehydrogenase [NAD] subunit alph... 59 5e-09
9IDH2_SCHPO (Q9USP8) Isocitrate dehydrogenase [NAD] subunit 2, mi... 59 9e-09
10IDH3A_MACFA (Q28480) Isocitrate dehydrogenase [NAD] subunit alph... 59 9e-09
11IDH_THET8 (P33197) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)... 58 2e-08
12IDH2_KLULA (O94230) Isocitrate dehydrogenase [NAD] subunit 2, mi... 55 1e-07
13LEU3_SOLTU (P29696) 3-isopropylmalate dehydrogenase, chloroplast... 53 4e-07
14IDH1_KLULA (O94229) Isocitrate dehydrogenase [NAD] subunit 1, mi... 52 1e-06
15IDH1_SCHPO (O13696) Isocitrate dehydrogenase [NAD] subunit 1, mi... 50 1e-06
16IDH1_YEAST (P28834) Isocitrate dehydrogenase [NAD] subunit 1, mi... 49 6e-06
17IDH3B_RAT (Q68FX0) Isocitrate dehydrogenase [NAD] subunit beta, ... 45 1e-05
18IDH1_AJECA (O13302) Isocitrate dehydrogenase [NAD] subunit 1, mi... 47 3e-05
19IDH3B_BOVIN (O77784) Isocitrate dehydrogenase [NAD] subunit beta... 45 8e-05
20IDH3B_MACFA (Q28479) Isocitrate dehydrogenase [NAD] subunit beta... 45 1e-04
21IDH3B_PONPY (Q5RBT4) Isocitrate dehydrogenase [NAD] subunit beta... 45 1e-04
22IDH3B_HUMAN (O43837) Isocitrate dehydrogenase [NAD] subunit beta... 45 1e-04
23IDH3G_RAT (P41565) Isocitrate dehydrogenase [NAD] subunit gamma,... 43 4e-04
24IDH3G_MACFA (P41564) Isocitrate dehydrogenase [NAD] subunit gamm... 43 5e-04
25IDH3G_MOUSE (P70404) Isocitrate dehydrogenase [NAD] subunit gamm... 43 5e-04
26IDH3G_HUMAN (P51553) Isocitrate dehydrogenase [NAD] subunit gamm... 43 5e-04
27IDH_RICCN (Q92IR7) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)... 42 7e-04
28IDH_ANASP (P50214) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)... 42 0.001
29IDH3B_CAEEL (Q93353) Probable isocitrate dehydrogenase [NAD] sub... 41 0.002
30IDH_ECOLI (P08200) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)... 40 0.003
31IDH_STAES (Q8CNX4) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)... 40 0.003
32IDH_STAEQ (Q5HNL1) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)... 40 0.003
33IDH3A_PIG (P56471) Isocitrate dehydrogenase [NAD] subunit alpha,... 40 0.004
34IDH_STAAW (Q8NW61) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)... 38 0.013
35IDH_STAAS (Q6G8N2) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)... 38 0.013
36IDH_STAAR (Q6GG12) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)... 38 0.013
37IDH_STAAN (P99167) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)... 38 0.013
38IDH_STAAM (P65099) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)... 38 0.013
39IDH_STAAC (Q5HF79) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)... 38 0.013
40IDH_SYNY3 (P80046) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)... 38 0.017
41IDH_BACSU (P39126) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)... 37 0.028
42IDH1_COLMA (P41560) Isocitrate dehydrogenase [NADP] 1 (EC 1.1.1.... 37 0.037
43IDH_CALNO (P96318) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)... 37 0.037
44IDH_RICPR (Q9ZDR0) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)... 37 0.037
45LEU3_MYCTU (P95313) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 36 0.048
46LEU3_MYCBO (P94929) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 36 0.048
47IDH_RICTY (Q68XA5) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)... 36 0.048
48IDH_ARCFU (O29610) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)... 36 0.048
49LEU3_DEIRA (Q9RTH9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 36 0.063
50LEU3_MYCPA (Q73VI1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 34 0.18
51IDH_STRSL (Q59985) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)... 34 0.18
52LEU3_CHRVO (Q7NUC2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 34 0.18
53LEU3_BORPE (Q7VY73) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 34 0.18
54LEU3_BORPA (Q7W929) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 34 0.18
55LEU3_BORBR (Q7WKH4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 34 0.18
56LEU3_SYNPX (Q7U840) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 34 0.24
57IDH_HELPJ (Q9ZN36) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)... 33 0.31
58IDH_AQUAE (O67480) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)... 33 0.41
59IDH_HELPY (P56063) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)... 33 0.53
60LRP11_HUMAN (Q86VZ4) Low-density lipoprotein receptor-related pr... 33 0.53
61LEU3_PROMT (Q46LE2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 33 0.53
62LEU3_SHIBS (Q326G2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 33 0.53
63LEU3_NOCFA (Q5YRX2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 33 0.53
64LEU3_THIDA (Q3SHL3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 33 0.53
65LEU3_ECOLI (P30125) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 33 0.53
66LEU3_ECOL6 (Q8FL76) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 33 0.53
67LEU3_ECO57 (Q8X9Z9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 33 0.53
68LEU3_CHLTE (P59028) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 32 0.70
69RSMB_DROME (Q05856) Small nuclear ribonucleoprotein-associated p... 32 0.70
70LEU3_ARCFU (O29627) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 32 0.70
71LEU3_AGRT5 (P24404) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 32 0.70
72DLPA_LEGPH (Q48806) Protein dlpA 32 0.91
73LEU3_SHISS (Q3Z5T7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 32 0.91
74LEU3_SHIDS (Q32K21) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 32 0.91
75MYO15_HUMAN (Q9UKN7) Myosin-15 (Myosin XV) (Unconventional myosi... 32 0.91
76LEU3_PSEHT (Q3IJS3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 32 0.91
77LEU3_SHIFL (Q83SP1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 32 0.91
78IDH_STRMU (Q59940) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)... 32 1.2
79LEU3_MYCLE (O33117) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 32 1.2
80LEU3_PHACH (O59930) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 32 1.2
81LEU3_BACHD (Q9K8E9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 32 1.2
82LEU3_THEFY (Q47SB4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 32 1.2
83LEU3_SALTY (P37412) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 31 1.6
84LEU3_SALCH (Q57TE7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 31 1.6
85LEU3_ACIAD (Q6FEV6) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 31 1.6
86KDSB_VIBCH (Q9KQX2) 3-deoxy-manno-octulosonate cytidylyltransfer... 31 1.6
87WASP_MOUSE (P70315) Wiskott-Aldrich syndrome protein homolog (WASp) 31 1.6
88LEU3_BRUSU (Q8FVF3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 31 1.6
89LEU3_BRUME (Q8YCX4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 31 1.6
90KDSB_VIBPA (Q87R14) 3-deoxy-manno-octulosonate cytidylyltransfer... 31 1.6
91LEU3_THEAQ (P24098) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 31 2.0
92LEU3_SALTI (Q8Z9I1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 31 2.0
93LEU3_SALPA (Q5PDG2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 31 2.0
94NMDE3_HUMAN (Q14957) Glutamate [NMDA] receptor subunit epsilon 3... 31 2.0
95LEU3_THETH (P61495) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 30 2.7
96LEU3_THET8 (Q5SIY4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 30 2.7
97LEU3_THET2 (P61494) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 30 2.7
98LEU3_PROMM (Q7V842) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 30 2.7
99SPN90_HUMAN (Q9NZQ3) SH3 adapter protein SPIN90 (NCK-interacting... 30 2.7
100LEU3_RALEJ (Q46YW0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 30 2.7
101LEU3_AZOSE (Q5P1J6) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 30 2.7
102TTUC5_AGRVI (O34295) Probable tartrate dehydrogenase/decarboxyla... 30 2.7
103TTUC4_AGRVI (P70792) Probable tartrate dehydrogenase/decarboxyla... 30 2.7
104TTUC3_AGRVI (O34296) Probable tartrate dehydrogenase/decarboxyla... 30 2.7
105TTUC2_AGRVI (P70787) Probable tartrate dehydrogenase/decarboxyla... 30 2.7
106TTUC1_AGRVI (Q44471) Probable tartrate dehydrogenase/decarboxyla... 30 2.7
107LEU3_BACSK (Q5WEN4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 30 2.7
108IDH3B_PIG (P56472) Isocitrate dehydrogenase [NAD] subunit beta, ... 30 3.5
109FBX41_HUMAN (Q8TF61) F-box only protein 41 30 3.5
110CSKI1_HUMAN (Q8WXD9) Caskin-1 (CASK-interacting protein 1) 30 3.5
111SENP3_HUMAN (Q9H4L4) Sentrin-specific protease 3 (EC 3.4.22.-) (... 30 3.5
112LEU3_RHIME (Q92KY8) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 30 3.5
113LEU3_CAUCR (Q9ABN3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 30 3.5
114Y1617_METMA (Q8PWH0) UPF0272 protein MM1617 30 3.5
115KDSB_YERPE (Q8ZGA4) 3-deoxy-manno-octulosonate cytidylyltransfer... 30 3.5
116LEU31_ARATH (Q9SA14) 3-isopropylmalate dehydrogenase 1, chloropl... 30 4.5
117LEU3_VIBVY (Q7MP78) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 30 4.5
118LEU3_VIBVU (Q8DEE0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 30 4.5
119LEU3_BRAJA (Q89X19) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 30 4.5
120LEU32_ARATH (P93832) 3-isopropylmalate dehydrogenase 2, chloropl... 30 4.5
121CENG1_HUMAN (Q99490) Centaurin-gamma 1 (ARF-GAP with GTP-binding... 30 4.5
122LEU3_METCA (Q606F4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 30 4.5
123LEU3_BRANA (P29102) 3-isopropylmalate dehydrogenase, chloroplast... 29 5.9
124LEU3_YERPS (Q66EM2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 29 5.9
125LEU3_YERPE (Q8ZIG9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 29 5.9
126HSLU_AQUAE (O66574) ATP-dependent hsl protease ATP-binding subun... 29 5.9
127MUCDL_RAT (Q9JIK1) Mucin and cadherin-like protein precursor (Mu... 29 5.9
128MUC2_RAT (Q62635) Mucin-2 precursor (Intestinal mucin 2) (Fragment) 29 5.9
129LEU3_PELCD (Q3A3B2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 29 5.9
130EFS_MOUSE (Q64355) Embryonal Fyn-associated substrate (SRC-inter... 29 7.7
131BAG3_MOUSE (Q9JLV1) BAG family molecular chaperone regulator 3 (... 29 7.7
132MUC2_HUMAN (Q02817) Mucin-2 precursor (Intestinal mucin 2) 29 7.7
133Y429_METAC (Q8TTK2) UPF0272 protein MA0429 29 7.7
134LEU3_GEOSL (Q748X2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 29 7.7
135UCRI_PROMM (Q7V654) Cytochrome b6-f complex iron-sulfur subunit ... 29 7.7
136SF3A2_HUMAN (Q15428) Splicing factor 3A subunit 2 (Spliceosome-a... 29 7.7
137LEU3_CORDI (Q6NHM7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 29 7.7
138LEU3_SYNP6 (Q5MZ40) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 29 7.7
139LEU3_SILPO (Q5LWZ5) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 26 9.9

>IDH3A_CAEEL (Q93714) Probable isocitrate dehydrogenase [NAD] subunit alpha,|
           mitochondrial precursor (EC 1.1.1.41) (Isocitric
           dehydrogenase) (NAD(+)-specific ICDH)
          Length = 358

 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 38/91 (41%), Positives = 51/91 (56%), Gaps = 5/91 (5%)
 Frame = +3

Query: 180 ARRTVTYMPRPGDGTPRPVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDV-----HG 344
           A  TV    R   G  R VTLIPGDGIGP ++ +V+++ EA  AP+ ++  DV       
Sbjct: 9   ASSTVGQSIRYSSGDVRRVTLIPGDGIGPEISASVQKIFEAADAPIAWDPVDVTPVKGRD 68

Query: 345 DMPAVPPAVIESIPRNKVCLKGGLATPVGGG 437
            +  +P   IE +  NKV LKG L TP+G G
Sbjct: 69  GVFRIPSRCIELMHANKVGLKGPLETPIGKG 99



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>IDH3A_DROME (Q9VWH4) Probable isocitrate dehydrogenase [NAD] subunit alpha,|
           mitochondrial precursor (EC 1.1.1.41) (Isocitric
           dehydrogenase) (NAD(+)-specific ICDH)
          Length = 377

 Score = 63.2 bits (152), Expect = 4e-10
 Identities = 33/75 (44%), Positives = 46/75 (61%), Gaps = 5/75 (6%)
 Frame = +3

Query: 228 RPVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDV-----HGDMPAVPPAVIESIPRN 392
           + VTLIPGDGIGP ++ AV+++  A + P+ +E  DV           +P A I+S+  N
Sbjct: 48  KKVTLIPGDGIGPEISAAVQKIFTAANVPIEWEAVDVTPVRGPDGKFGIPQAAIDSVNTN 107

Query: 393 KVCLKGGLATPVGGG 437
           K+ LKG L TPVG G
Sbjct: 108 KIGLKGPLMTPVGKG 122



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>IDH3A_BOVIN (P41563) Isocitrate dehydrogenase [NAD] subunit alpha,|
           mitochondrial precursor (EC 1.1.1.41) (Isocitric
           dehydrogenase) (NAD(+)-specific ICDH) (Isocitrate
           dehydrogenase subunits 3/4)
          Length = 366

 Score = 62.4 bits (150), Expect = 6e-10
 Identities = 36/92 (39%), Positives = 51/92 (55%), Gaps = 5/92 (5%)
 Frame = +3

Query: 177 GARRTVTYMPRPGDGTPRPVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDV-----H 341
           GA      + R   G  + VTLIPGDGIGP ++ AV ++ +A  AP+ +E  +V      
Sbjct: 15  GAFHNQKQVTRGFAGGVKTVTLIPGDGIGPEISAAVMKIFDAAKAPIQWEERNVAAIQGP 74

Query: 342 GDMPAVPPAVIESIPRNKVCLKGGLATPVGGG 437
           G    +PP   ES+ +NK+ LKG L TP+  G
Sbjct: 75  GGKWMIPPEAKESMDKNKMGLKGPLKTPIAAG 106



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>IDH3A_RAT (Q99NA5) Isocitrate dehydrogenase [NAD] subunit alpha,|
           mitochondrial precursor (EC 1.1.1.41) (Isocitric
           dehydrogenase) (NAD(+)-specific ICDH)
          Length = 366

 Score = 61.6 bits (148), Expect = 1e-09
 Identities = 35/92 (38%), Positives = 51/92 (55%), Gaps = 5/92 (5%)
 Frame = +3

Query: 177 GARRTVTYMPRPGDGTPRPVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDV-----H 341
           GA      + R   G  + VTLIPGDGIGP ++ +V ++ +A  AP+ +E  +V      
Sbjct: 15  GAFHNTKQVTRGFAGGVQTVTLIPGDGIGPEISASVMKIFDAAKAPIQWEERNVTAIQGP 74

Query: 342 GDMPAVPPAVIESIPRNKVCLKGGLATPVGGG 437
           G    +PP   ES+ +NK+ LKG L TP+  G
Sbjct: 75  GGKWMIPPEAKESMDKNKMGLKGPLKTPIAAG 106



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>IDH3A_MOUSE (Q9D6R2) Isocitrate dehydrogenase [NAD] subunit alpha,|
           mitochondrial precursor (EC 1.1.1.41) (Isocitric
           dehydrogenase) (NAD(+)-specific ICDH)
          Length = 366

 Score = 61.6 bits (148), Expect = 1e-09
 Identities = 35/92 (38%), Positives = 51/92 (55%), Gaps = 5/92 (5%)
 Frame = +3

Query: 177 GARRTVTYMPRPGDGTPRPVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDV-----H 341
           GA      + R   G  + VTLIPGDGIGP ++ +V ++ +A  AP+ +E  +V      
Sbjct: 15  GAFHNTKQVTRGFAGGVQTVTLIPGDGIGPEISASVMKIFDAAKAPIQWEERNVTAIQGP 74

Query: 342 GDMPAVPPAVIESIPRNKVCLKGGLATPVGGG 437
           G    +PP   ES+ +NK+ LKG L TP+  G
Sbjct: 75  GGKWMIPPEAKESMDKNKMGLKGPLKTPIAAG 106



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>IDH2_YEAST (P28241) Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial|
           precursor (EC 1.1.1.41) (Isocitric dehydrogenase)
           (NAD(+)-specific ICDH)
          Length = 369

 Score = 59.7 bits (143), Expect = 4e-09
 Identities = 31/85 (36%), Positives = 50/85 (58%), Gaps = 5/85 (5%)
 Frame = +3

Query: 198 YMPRPGDGTPR-PVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVH----GDMPAVP 362
           Y  +P   T +  V+ I GDGIGP ++ +V+++  A + P+ +E+ DV       +  +P
Sbjct: 26  YTGKPNPSTGKYTVSFIEGDGIGPEISKSVKKIFSAANVPIEWESCDVSPIFVNGLTTIP 85

Query: 363 PAVIESIPRNKVCLKGGLATPVGGG 437
              ++SI +N V LKG LATP+G G
Sbjct: 86  DPAVQSITKNLVALKGPLATPIGKG 110



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>IDH3A_PONPY (Q5R678) Isocitrate dehydrogenase [NAD] subunit alpha,|
           mitochondrial precursor (EC 1.1.1.41) (Isocitric
           dehydrogenase) (NAD(+)-specific ICDH)
          Length = 366

 Score = 59.3 bits (142), Expect = 5e-09
 Identities = 35/92 (38%), Positives = 50/92 (54%), Gaps = 5/92 (5%)
 Frame = +3

Query: 177 GARRTVTYMPRPGDGTPRPVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDV-----H 341
           GA      + R   G  + VTLIPGDGIGP ++ AV ++ +A  AP+ +E  +V      
Sbjct: 15  GAFHNPKQVTRGFTGGVQTVTLIPGDGIGPEISAAVMKIFDAAKAPIQWEERNVTAIQGP 74

Query: 342 GDMPAVPPAVIESIPRNKVCLKGGLATPVGGG 437
           G    +P    ES+ +NK+ LKG L TP+  G
Sbjct: 75  GGKWMIPSEAKESMDKNKMGLKGPLKTPIAAG 106



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>IDH3A_HUMAN (P50213) Isocitrate dehydrogenase [NAD] subunit alpha,|
           mitochondrial precursor (EC 1.1.1.41) (Isocitric
           dehydrogenase) (NAD(+)-specific ICDH)
          Length = 366

 Score = 59.3 bits (142), Expect = 5e-09
 Identities = 35/92 (38%), Positives = 50/92 (54%), Gaps = 5/92 (5%)
 Frame = +3

Query: 177 GARRTVTYMPRPGDGTPRPVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDV-----H 341
           GA      + R   G  + VTLIPGDGIGP ++ AV ++ +A  AP+ +E  +V      
Sbjct: 15  GAFHNPKQVTRGFTGGVQTVTLIPGDGIGPEISAAVMKIFDAAKAPIQWEERNVTAIQGP 74

Query: 342 GDMPAVPPAVIESIPRNKVCLKGGLATPVGGG 437
           G    +P    ES+ +NK+ LKG L TP+  G
Sbjct: 75  GGKWMIPSEAKESMDKNKMGLKGPLKTPIAAG 106



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>IDH2_SCHPO (Q9USP8) Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial|
           precursor (EC 1.1.1.41) (Isocitric dehydrogenase)
           (NAD(+)-specific ICDH)
          Length = 378

 Score = 58.5 bits (140), Expect = 9e-09
 Identities = 30/72 (41%), Positives = 43/72 (59%), Gaps = 4/72 (5%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVH----GDMPAVPPAVIESIPRNKVC 401
           VT+I GDGIGP +  +VE++ +A   P+ +E   V+         +P    ES+ +NKV 
Sbjct: 48  VTMIAGDGIGPEIAQSVERIFKAAKVPIEWERVKVYPILKNGTTTIPDDAKESVRKNKVA 107

Query: 402 LKGGLATPVGGG 437
           LKG LATP+G G
Sbjct: 108 LKGPLATPIGKG 119



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>IDH3A_MACFA (Q28480) Isocitrate dehydrogenase [NAD] subunit alpha,|
           mitochondrial precursor (EC 1.1.1.41) (Isocitric
           dehydrogenase) (NAD(+)-specific ICDH) (Fragment)
          Length = 347

 Score = 58.5 bits (140), Expect = 9e-09
 Identities = 32/78 (41%), Positives = 46/78 (58%), Gaps = 5/78 (6%)
 Frame = +3

Query: 219 GTPRPVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDV-----HGDMPAVPPAVIESI 383
           G  + VTLIPGDGIGP ++ AV ++ +A  AP+ +E  +V      G    +P    ES+
Sbjct: 10  GGVQTVTLIPGDGIGPEISAAVMKIFDAAKAPIQWEERNVTAIQGPGGKWMIPSEAKESM 69

Query: 384 PRNKVCLKGGLATPVGGG 437
            +NK+ LKG L TP+  G
Sbjct: 70  DKNKMGLKGPLKTPIAAG 87



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>IDH_THET8 (P33197) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)|
           (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
           ICDH) (IDP)
          Length = 496

 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 33/74 (44%), Positives = 42/74 (56%), Gaps = 6/74 (8%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDV------HGDMPAVPPAVIESIPRNK 395
           +T+IPGDGIGP    A  +V+EA  AP+ +E  +        G    VP   IESI + +
Sbjct: 22  ITVIPGDGIGPECVEATLKVLEAAKAPLAYEVREAGASVFRRGIASGVPQETIESIRKTR 81

Query: 396 VCLKGGLATPVGGG 437
           V LKG L TPVG G
Sbjct: 82  VVLKGPLETPVGYG 95



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>IDH2_KLULA (O94230) Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial|
           precursor (EC 1.1.1.41) (Isocitric dehydrogenase)
           (NAD(+)-specific ICDH)
          Length = 368

 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 29/83 (34%), Positives = 45/83 (54%), Gaps = 10/83 (12%)
 Frame = +3

Query: 219 GTPRP------VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVH----GDMPAVPPA 368
           G P P      V+ I GDG+GP ++ +V+ +  A   P+ +E+ DV       +  +P  
Sbjct: 27  GKPNPKTGKYTVSFIEGDGVGPEISKSVKAIFSAAKVPIEWESCDVSPIFVNGLTTIPDP 86

Query: 369 VIESIPRNKVCLKGGLATPVGGG 437
            + SI +N + LKG LATP+G G
Sbjct: 87  AVASINKNLIALKGPLATPIGKG 109



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>LEU3_SOLTU (P29696) 3-isopropylmalate dehydrogenase, chloroplast precursor (EC|
           1.1.1.85) (Beta-IPM dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 357

 Score = 53.1 bits (126), Expect = 4e-07
 Identities = 28/72 (38%), Positives = 42/72 (58%), Gaps = 5/72 (6%)
 Frame = +3

Query: 237 TLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHGDMPAVPPAV-----IESIPRNKVC 401
           TL PGDGIGP +  +V Q+ +    P+ +E + V  ++     +      +ES+ RNKV 
Sbjct: 40  TLFPGDGIGPEIAESVRQIFKVAEVPIEWEEHYVGTEVDPRTNSFLTWESLESVRRNKVG 99

Query: 402 LKGGLATPVGGG 437
           LKG +ATP+G G
Sbjct: 100 LKGPMATPIGKG 111



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>IDH1_KLULA (O94229) Isocitrate dehydrogenase [NAD] subunit 1, mitochondrial|
           precursor (EC 1.1.1.41) (Isocitric dehydrogenase)
           (NAD(+)-specific ICDH)
          Length = 361

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 29/65 (44%), Positives = 40/65 (61%), Gaps = 1/65 (1%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHG-DMPAVPPAVIESIPRNKVCLKG 410
           VTLIPGDG+G  VT +V ++ E  + P+ +ET D+ G +        +ES+ RNKV LKG
Sbjct: 32  VTLIPGDGVGKEVTDSVVKIFENENIPIDWETIDISGLENTENVQRAVESLKRNKVGLKG 91

Query: 411 GLATP 425
              TP
Sbjct: 92  IWHTP 96



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>IDH1_SCHPO (O13696) Isocitrate dehydrogenase [NAD] subunit 1, mitochondrial|
           precursor (EC 1.1.1.41) (Isocitric dehydrogenase)
           (NAD(+)-specific ICDH)
          Length = 356

 Score = 50.1 bits (118), Expect(2) = 1e-06
 Identities = 31/74 (41%), Positives = 39/74 (52%), Gaps = 6/74 (8%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHG------DMPAVPPAVIESIPRNK 395
           VTLIPGDGIG   + AV ++ +  + P+ FE  DV G               I+S+ RNK
Sbjct: 23  VTLIPGDGIGRETSNAVTEIFKTANVPIEFEEIDVTGMEKNNKSSGDALHEAIQSLKRNK 82

Query: 396 VCLKGGLATPVGGG 437
           V LKG L TP   G
Sbjct: 83  VGLKGILFTPFEKG 96



 Score = 20.8 bits (42), Expect(2) = 1e-06
 Identities = 8/10 (80%), Positives = 10/10 (100%)
 Frame = +2

Query: 458 LRKELDLFAS 487
           LRKELD++AS
Sbjct: 105 LRKELDIYAS 114



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>IDH1_YEAST (P28834) Isocitrate dehydrogenase [NAD] subunit 1, mitochondrial|
           precursor (EC 1.1.1.41) (Isocitric dehydrogenase)
           (NAD(+)-specific ICDH)
          Length = 360

 Score = 49.3 bits (116), Expect = 6e-06
 Identities = 27/65 (41%), Positives = 39/65 (60%), Gaps = 1/65 (1%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDV-HGDMPAVPPAVIESIPRNKVCLKG 410
           VTLIPGDG+G  +T +V  + EA + P+ +ET ++   D        +ES+ RNK+ LKG
Sbjct: 31  VTLIPGDGVGKEITDSVRTIFEAENIPIDWETINIKQTDHKEGVYEAVESLKRNKIGLKG 90

Query: 411 GLATP 425
              TP
Sbjct: 91  LWHTP 95



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>IDH3B_RAT (Q68FX0) Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial|
           precursor (EC 1.1.1.41) (Isocitric dehydrogenase)
           (NAD(+)-specific ICDH)
          Length = 385

 Score = 44.7 bits (104), Expect(2) = 1e-05
 Identities = 24/70 (34%), Positives = 39/70 (55%), Gaps = 4/70 (5%)
 Frame = +3

Query: 231 PVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHGDMPAVP----PAVIESIPRNKV 398
           PVT++PGDG+GP +  AV++V +A   PV F+ + +              V+ S+  NKV
Sbjct: 50  PVTMLPGDGVGPELMHAVKEVFKAAAVPVEFKEHHLSEVQNMASEEKLEQVLSSMKENKV 109

Query: 399 CLKGGLATPV 428
            + G + TP+
Sbjct: 110 AIIGKIYTPM 119



 Score = 22.7 bits (47), Expect(2) = 1e-05
 Identities = 9/12 (75%), Positives = 12/12 (100%)
 Frame = +2

Query: 452 MQLRKELDLFAS 487
           MQLR++LDLFA+
Sbjct: 130 MQLRRKLDLFAN 141



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>IDH1_AJECA (O13302) Isocitrate dehydrogenase [NAD] subunit 1, mitochondrial|
           precursor (EC 1.1.1.41) (Isocitric dehydrogenase)
           (NAD(+)-specific ICDH)
          Length = 388

 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 30/71 (42%), Positives = 40/71 (56%), Gaps = 6/71 (8%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHG------DMPAVPPAVIESIPRNK 395
           VTLIPGDGIG  V  +V+ + +A + P+ +E  DV G          +    I S+ RNK
Sbjct: 54  VTLIPGDGIGTEVAESVKTIFKADNVPIEWEQVDVSGLDAGNKHSEDLFKESIASLKRNK 113

Query: 396 VCLKGGLATPV 428
           + LKG L TPV
Sbjct: 114 LGLKGILHTPV 124



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>IDH3B_BOVIN (O77784) Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial|
           precursor (EC 1.1.1.41) (Isocitric dehydrogenase)
           (NAD(+)-specific ICDH) (NAD(+)-isocitrate dehydrogenase
           subunit 1) (IDH1)
          Length = 385

 Score = 45.4 bits (106), Expect = 8e-05
 Identities = 24/70 (34%), Positives = 39/70 (55%), Gaps = 4/70 (5%)
 Frame = +3

Query: 231 PVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHGDMPAVP----PAVIESIPRNKV 398
           PVT++PGDG+GP +  AV++V +A   PV F+ + +              V+ S+  NKV
Sbjct: 50  PVTMLPGDGVGPELMHAVKEVFKAASVPVEFQEHHLSEVQNMASEEKLEQVLSSMKENKV 109

Query: 399 CLKGGLATPV 428
            + G + TP+
Sbjct: 110 AIIGKIHTPM 119



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>IDH3B_MACFA (Q28479) Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial|
           precursor (EC 1.1.1.41) (Isocitric dehydrogenase)
           (NAD(+)-specific ICDH) (Fragment)
          Length = 381

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 24/70 (34%), Positives = 39/70 (55%), Gaps = 4/70 (5%)
 Frame = +3

Query: 231 PVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHGDMPAVP----PAVIESIPRNKV 398
           PVT++PGDG+GP +  AV++V +A   PV F+ + +              V+ S+  NKV
Sbjct: 48  PVTMLPGDGVGPELMHAVKEVFKAAAVPVEFQEHHLSEVQNMASEEKLEQVLSSMKENKV 107

Query: 399 CLKGGLATPV 428
            + G + TP+
Sbjct: 108 AIIGKIHTPM 117



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>IDH3B_PONPY (Q5RBT4) Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial|
           precursor (EC 1.1.1.41) (Isocitric dehydrogenase)
           (NAD(+)-specific ICDH)
          Length = 385

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 24/70 (34%), Positives = 39/70 (55%), Gaps = 4/70 (5%)
 Frame = +3

Query: 231 PVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHGDMPAVP----PAVIESIPRNKV 398
           PVT++PGDG+GP +  AV++V +A   PV F+ + +              V+ S+  NKV
Sbjct: 50  PVTMLPGDGVGPELMHAVKEVFKAAAVPVEFQEHHLSEVQNMASEEKLEQVLSSMKENKV 109

Query: 399 CLKGGLATPV 428
            + G + TP+
Sbjct: 110 AIIGKIHTPM 119



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>IDH3B_HUMAN (O43837) Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial|
           precursor (EC 1.1.1.41) (Isocitric dehydrogenase)
           (NAD(+)-specific ICDH)
          Length = 385

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 24/70 (34%), Positives = 39/70 (55%), Gaps = 4/70 (5%)
 Frame = +3

Query: 231 PVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHGDMPAVP----PAVIESIPRNKV 398
           PVT++PGDG+GP +  AV++V +A   PV F+ + +              V+ S+  NKV
Sbjct: 50  PVTMLPGDGVGPELMHAVKEVFKAAAVPVEFQEHHLSEVQNMASEEKLEQVLSSMKENKV 109

Query: 399 CLKGGLATPV 428
            + G + TP+
Sbjct: 110 AIIGKIHTPM 119



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>IDH3G_RAT (P41565) Isocitrate dehydrogenase [NAD] subunit gamma,|
           mitochondrial precursor (EC 1.1.1.41) (Isocitric
           dehydrogenase) (NAD(+)-specific ICDH)
          Length = 393

 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 33/96 (34%), Positives = 48/96 (50%), Gaps = 2/96 (2%)
 Frame = +3

Query: 141 VASAPSLPGHGGGARRTVTYMPRPGDGTPRPVTLIPGDGIGPLVTGAVEQVMEAMHAPVY 320
           V +A   P     +++T+   P    G    VT+IPGDGIGP +   V+ V      PV 
Sbjct: 28  VLAAHEAPRRSISSQQTIP--PSAKYGGRHTVTMIPGDGIGPELMLHVKSVFRHACVPVD 85

Query: 321 FETYDV--HGDMPAVPPAVIESIPRNKVCLKGGLAT 422
           FE   V  + D   +  A++ +I RN+V LKG + T
Sbjct: 86  FEEVHVSSNADEEDIRNAIM-AIRRNRVALKGNIET 120



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>IDH3G_MACFA (P41564) Isocitrate dehydrogenase [NAD] subunit gamma,|
           mitochondrial precursor (EC 1.1.1.41) (Isocitric
           dehydrogenase) (NAD(+)-specific ICDH) (Fragment)
          Length = 355

 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 30/78 (38%), Positives = 40/78 (51%), Gaps = 2/78 (2%)
 Frame = +3

Query: 195 TYMPRPGDGTPRPVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDV--HGDMPAVPPA 368
           T  P    G    VT+IPGDGIGP +   V+ V      PV FE   V  + D   +  A
Sbjct: 6   TIPPSAKYGGRHTVTMIPGDGIGPELMLHVKSVFRHACVPVDFEEVHVSSNADEEDIRNA 65

Query: 369 VIESIPRNKVCLKGGLAT 422
           ++ +I RN+V LKG + T
Sbjct: 66  IM-AIRRNRVALKGNIET 82



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>IDH3G_MOUSE (P70404) Isocitrate dehydrogenase [NAD] subunit gamma,|
           mitochondrial precursor (EC 1.1.1.41) (Isocitric
           dehydrogenase) (NAD(+)-specific ICDH)
          Length = 393

 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 30/78 (38%), Positives = 40/78 (51%), Gaps = 2/78 (2%)
 Frame = +3

Query: 195 TYMPRPGDGTPRPVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDV--HGDMPAVPPA 368
           T  P    G    VT+IPGDGIGP +   V+ V      PV FE   V  + D   +  A
Sbjct: 44  TIPPSAKYGGRHTVTMIPGDGIGPELMLHVKSVFRHACVPVDFEEVHVSSNADEEDIRNA 103

Query: 369 VIESIPRNKVCLKGGLAT 422
           ++ +I RN+V LKG + T
Sbjct: 104 IM-AIRRNRVALKGNIET 120



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>IDH3G_HUMAN (P51553) Isocitrate dehydrogenase [NAD] subunit gamma,|
           mitochondrial precursor (EC 1.1.1.41) (Isocitric
           dehydrogenase) (NAD(+)-specific ICDH)
          Length = 393

 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 30/78 (38%), Positives = 40/78 (51%), Gaps = 2/78 (2%)
 Frame = +3

Query: 195 TYMPRPGDGTPRPVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDV--HGDMPAVPPA 368
           T  P    G    VT+IPGDGIGP +   V+ V      PV FE   V  + D   +  A
Sbjct: 44  TIPPSAKYGGRHTVTMIPGDGIGPELMLHVKSVFRHACVPVDFEEVHVSSNADEEDIRNA 103

Query: 369 VIESIPRNKVCLKGGLAT 422
           ++ +I RN+V LKG + T
Sbjct: 104 IM-AIRRNRVALKGNIET 120



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>IDH_RICCN (Q92IR7) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)|
           (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
           ICDH) (IDP)
          Length = 483

 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 25/75 (33%), Positives = 36/75 (48%), Gaps = 6/75 (8%)
 Frame = +3

Query: 231 PVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHGDM------PAVPPAVIESIPRN 392
           P+T+  GDGIGP +  AV  ++    A +  ET +V   +        +     ESI R 
Sbjct: 6   PITIAYGDGIGPEIMEAVLYILRKAEARIRLETIEVGEKLYKKHYTSGISEESWESIQRT 65

Query: 393 KVCLKGGLATPVGGG 437
            + LK  + TP GGG
Sbjct: 66  GIILKAPITTPQGGG 80



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>IDH_ANASP (P50214) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)|
           (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
           ICDH) (IDP)
          Length = 473

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 27/83 (32%), Positives = 40/83 (48%), Gaps = 14/83 (16%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVY--------FETY------DVHGDMPAVPPAV 371
           +  I GDG G  +  A E+V++A  A  Y        F+ Y      D++G    +P   
Sbjct: 29  IPFIRGDGTGIDIWPATEKVLDAAVAKAYQGKRKISWFKVYAGDEACDLYGTYQYLPEDT 88

Query: 372 IESIPRNKVCLKGGLATPVGGGV 440
           + +I    V +KG L TPVGGG+
Sbjct: 89  LTAIREYGVAIKGPLTTPVGGGI 111



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>IDH3B_CAEEL (Q93353) Probable isocitrate dehydrogenase [NAD] subunit beta,|
           mitochondrial precursor (EC 1.1.1.41) (Isocitric
           dehydrogenase) (NAD(+)-specific ICDH)
          Length = 379

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 35/109 (32%), Positives = 53/109 (48%), Gaps = 12/109 (11%)
 Frame = +3

Query: 126 LLRRLVAS----APSLPG--HGGGARRTVTYMPRPGDGTPRP--VTLIPGDGIGPLVTGA 281
           +L R V+S    AP   G  +   +R+     PRP     +   VT+IPGDG+GP +   
Sbjct: 1   MLSRTVSSLSRVAPQTLGAVNAASSRQYSITAPRPPTELNQKLKVTIIPGDGVGPELIYT 60

Query: 282 VEQVMEAMHAPVYFETY---DVHGDMPAVPPAVIESIPR-NKVCLKGGL 416
           V+ +++    P+ FE     +VH    +     +ESI R N V LKG +
Sbjct: 61  VQDIVKQTGIPIEFEEIFLSEVHYTRSSSIENAVESIGRNNNVALKGAI 109



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>IDH_ECOLI (P08200) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)|
           (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
           ICDH) (IDP)
          Length = 416

 Score = 40.4 bits (93), Expect = 0.003
 Identities = 28/83 (33%), Positives = 40/83 (48%), Gaps = 14/83 (16%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVY--------FETY------DVHGDMPAVPPAV 371
           +  I GDGIG  VT A+ +V++A     Y         E Y       V+G    +P   
Sbjct: 29  IPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERKISWMEIYTGEKSTQVYGQDVWLPAET 88

Query: 372 IESIPRNKVCLKGGLATPVGGGV 440
           ++ I   +V +KG L TPVGGG+
Sbjct: 89  LDLIREYRVAIKGPLTTPVGGGI 111



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>IDH_STAES (Q8CNX4) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)|
           (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
           ICDH) (IDP)
          Length = 422

 Score = 40.0 bits (92), Expect = 0.003
 Identities = 25/83 (30%), Positives = 39/83 (46%), Gaps = 14/83 (16%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYF--------------ETYDVHGDMPAVPPAV 371
           +  I GDGIGP +  A  +V++A     Y               + YD  G+   +P   
Sbjct: 21  IPFIIGDGIGPDIWKAASRVIDAAVEKAYNGEKRIEWKEVLAGQKAYDETGEW--LPQET 78

Query: 372 IESIPRNKVCLKGGLATPVGGGV 440
           +E+I    + +KG L TP+GGG+
Sbjct: 79  LETIKEYLIAVKGPLTTPIGGGI 101



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>IDH_STAEQ (Q5HNL1) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)|
           (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
           ICDH) (IDP)
          Length = 422

 Score = 40.0 bits (92), Expect = 0.003
 Identities = 25/83 (30%), Positives = 39/83 (46%), Gaps = 14/83 (16%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYF--------------ETYDVHGDMPAVPPAV 371
           +  I GDGIGP +  A  +V++A     Y               + YD  G+   +P   
Sbjct: 21  IPFIIGDGIGPDIWKAASRVIDAAVEKAYNGEKRIEWKEVLAGQKAYDETGEW--LPQET 78

Query: 372 IESIPRNKVCLKGGLATPVGGGV 440
           +E+I    + +KG L TP+GGG+
Sbjct: 79  LETIKEYLIAVKGPLTTPIGGGI 101



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>IDH3A_PIG (P56471) Isocitrate dehydrogenase [NAD] subunit alpha,|
           mitochondrial (EC 1.1.1.41) (Isocitric dehydrogenase)
           (NAD(+)-specific ICDH) (Fragments)
          Length = 90

 Score = 39.7 bits (91), Expect = 0.004
 Identities = 17/33 (51%), Positives = 24/33 (72%)
 Frame = +3

Query: 219 GTPRPVTLIPGDGIGPLVTGAVEQVMEAMHAPV 317
           G  + VTLIPGDGIGP ++ AV ++ +A  AP+
Sbjct: 2   GGVKTVTLIPGDGIGPEISAAVMKIFDAAKAPI 34



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>IDH_STAAW (Q8NW61) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)|
           (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
           ICDH) (IDP)
          Length = 422

 Score = 38.1 bits (87), Expect = 0.013
 Identities = 23/83 (27%), Positives = 39/83 (46%), Gaps = 14/83 (16%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYF--------------ETYDVHGDMPAVPPAV 371
           +  I GDGIGP +  A  +V++A     Y               + +D  G+   +P   
Sbjct: 21  IPFIIGDGIGPDIWKAASRVIDAAVEKAYNGEKRIEWKEVLAGQKAFDTTGEW--LPQET 78

Query: 372 IESIPRNKVCLKGGLATPVGGGV 440
           +++I    + +KG L TP+GGG+
Sbjct: 79  LDTIKEYLIAVKGPLTTPIGGGI 101



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>IDH_STAAS (Q6G8N2) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)|
           (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
           ICDH) (IDP)
          Length = 422

 Score = 38.1 bits (87), Expect = 0.013
 Identities = 23/83 (27%), Positives = 39/83 (46%), Gaps = 14/83 (16%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYF--------------ETYDVHGDMPAVPPAV 371
           +  I GDGIGP +  A  +V++A     Y               + +D  G+   +P   
Sbjct: 21  IPFIIGDGIGPDIWKAASRVIDAAVEKAYNGEKRIEWKEVLAGQKAFDTTGEW--LPQET 78

Query: 372 IESIPRNKVCLKGGLATPVGGGV 440
           +++I    + +KG L TP+GGG+
Sbjct: 79  LDTIKEYLIAVKGPLTTPIGGGI 101



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>IDH_STAAR (Q6GG12) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)|
           (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
           ICDH) (IDP)
          Length = 422

 Score = 38.1 bits (87), Expect = 0.013
 Identities = 23/83 (27%), Positives = 39/83 (46%), Gaps = 14/83 (16%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYF--------------ETYDVHGDMPAVPPAV 371
           +  I GDGIGP +  A  +V++A     Y               + +D  G+   +P   
Sbjct: 21  IPFIIGDGIGPDIWKAASRVIDAAVEKAYNGEKRIEWKEVLAGQKAFDTTGEW--LPQET 78

Query: 372 IESIPRNKVCLKGGLATPVGGGV 440
           +++I    + +KG L TP+GGG+
Sbjct: 79  LDTIKEYLIAVKGPLTTPIGGGI 101



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>IDH_STAAN (P99167) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)|
           (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
           ICDH) (IDP)
          Length = 422

 Score = 38.1 bits (87), Expect = 0.013
 Identities = 23/83 (27%), Positives = 39/83 (46%), Gaps = 14/83 (16%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYF--------------ETYDVHGDMPAVPPAV 371
           +  I GDGIGP +  A  +V++A     Y               + +D  G+   +P   
Sbjct: 21  IPFIIGDGIGPDIWKAASRVIDAAVEKAYNGEKRIEWKEVLAGQKAFDTTGEW--LPQET 78

Query: 372 IESIPRNKVCLKGGLATPVGGGV 440
           +++I    + +KG L TP+GGG+
Sbjct: 79  LDTIKEYLIAVKGPLTTPIGGGI 101



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>IDH_STAAM (P65099) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)|
           (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
           ICDH) (IDP)
          Length = 422

 Score = 38.1 bits (87), Expect = 0.013
 Identities = 23/83 (27%), Positives = 39/83 (46%), Gaps = 14/83 (16%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYF--------------ETYDVHGDMPAVPPAV 371
           +  I GDGIGP +  A  +V++A     Y               + +D  G+   +P   
Sbjct: 21  IPFIIGDGIGPDIWKAASRVIDAAVEKAYNGEKRIEWKEVLAGQKAFDTTGEW--LPQET 78

Query: 372 IESIPRNKVCLKGGLATPVGGGV 440
           +++I    + +KG L TP+GGG+
Sbjct: 79  LDTIKEYLIAVKGPLTTPIGGGI 101



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>IDH_STAAC (Q5HF79) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)|
           (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
           ICDH) (IDP)
          Length = 422

 Score = 38.1 bits (87), Expect = 0.013
 Identities = 23/83 (27%), Positives = 39/83 (46%), Gaps = 14/83 (16%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYF--------------ETYDVHGDMPAVPPAV 371
           +  I GDGIGP +  A  +V++A     Y               + +D  G+   +P   
Sbjct: 21  IPFIIGDGIGPDIWKAASRVIDAAVEKAYNGEKRIEWKEVLAGQKAFDTTGEW--LPQET 78

Query: 372 IESIPRNKVCLKGGLATPVGGGV 440
           +++I    + +KG L TP+GGG+
Sbjct: 79  LDTIKEYLIAVKGPLTTPIGGGI 101



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>IDH_SYNY3 (P80046) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)|
           (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
           ICDH) (IDP)
          Length = 475

 Score = 37.7 bits (86), Expect = 0.017
 Identities = 26/83 (31%), Positives = 37/83 (44%), Gaps = 14/83 (16%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVY--------FETY------DVHGDMPAVPPAV 371
           +  I GDG G  +  A E V+ A  A  Y        F+ Y      +++G     P   
Sbjct: 29  IPYIRGDGTGVDIWPATELVINAAIAKAYGGREEINWFKVYAGDEACELYGTYQIFPEDT 88

Query: 372 IESIPRNKVCLKGGLATPVGGGV 440
           + +I    V +KG L TPVGGG+
Sbjct: 89  LTAIKEYGVAIKGPLTTPVGGGI 111



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>IDH_BACSU (P39126) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)|
           (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
           ICDH) (IDP)
          Length = 423

 Score = 37.0 bits (84), Expect = 0.028
 Identities = 24/83 (28%), Positives = 37/83 (44%), Gaps = 14/83 (16%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYF--------------ETYDVHGDMPAVPPAV 371
           +  I GDG GP +  A  +V+EA     Y               + Y+  G+   +P   
Sbjct: 22  IPFIEGDGTGPDIWNAASKVLEAAVEKAYKGEKKITWKEVYAGEKAYNKTGEW--LPAET 79

Query: 372 IESIPRNKVCLKGGLATPVGGGV 440
           ++ I    + +KG L TPVGGG+
Sbjct: 80  LDVIREYFIAIKGPLTTPVGGGI 102



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>IDH1_COLMA (P41560) Isocitrate dehydrogenase [NADP] 1 (EC 1.1.1.42)|
           (Oxalosuccinate decarboxylase 1) (IDH-I)
           (NADP(+)-specific ICDH 1) (IDP-1)
          Length = 414

 Score = 36.6 bits (83), Expect = 0.037
 Identities = 27/83 (32%), Positives = 38/83 (45%), Gaps = 14/83 (16%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVY-----FETYDVHGDMPA---------VPPAV 371
           +  I GDGIG  VT  + +V+ A  A  Y      E  +V+    A         +P   
Sbjct: 28  IPYIEGDGIGVDVTPPMLKVVNAAVAKAYGGDRKIEWLEVYAGEKATKMYDSETWLPEET 87

Query: 372 IESIPRNKVCLKGGLATPVGGGV 440
           +  +   KV +KG L TPVGGG+
Sbjct: 88  LNILQEYKVSIKGPLTTPVGGGM 110



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>IDH_CALNO (P96318) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)|
           (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
           ICDH) (IDP)
          Length = 429

 Score = 36.6 bits (83), Expect = 0.037
 Identities = 25/80 (31%), Positives = 38/80 (47%), Gaps = 12/80 (15%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFET-----YDVHGDMPA-------VPPAVIE 377
           V    GDGIGP +  + ++V++A     Y  T     ++V     A       +P   ++
Sbjct: 35  VAYFKGDGIGPEIVESAKKVLDAAVDKAYGGTRRIVWWEVTAGEEAQKECGSLLPDGTLQ 94

Query: 378 SIPRNKVCLKGGLATPVGGG 437
           +    +V LKG L TPVGGG
Sbjct: 95  AFKLARVNLKGPLTTPVGGG 114



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>IDH_RICPR (Q9ZDR0) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)|
           (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
           ICDH) (IDP)
          Length = 483

 Score = 36.6 bits (83), Expect = 0.037
 Identities = 22/75 (29%), Positives = 34/75 (45%), Gaps = 6/75 (8%)
 Frame = +3

Query: 231 PVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHGDM------PAVPPAVIESIPRN 392
           P+T+  GDGIGP +  AV  ++    A +  ET +V   +        +     + I R 
Sbjct: 6   PITIAYGDGIGPEIMEAVLYILRKAEARISLETIEVGEKLYKKHYTSGISEESWDVIQRT 65

Query: 393 KVCLKGGLATPVGGG 437
            + LK  + TP  GG
Sbjct: 66  GIILKAPITTPQSGG 80



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>LEU3_MYCTU (P95313) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 336

 Score = 36.2 bits (82), Expect = 0.048
 Identities = 20/69 (28%), Positives = 34/69 (49%), Gaps = 5/69 (7%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDV-----HGDMPAVPPAVIESIPRNKV 398
           + +I GDGIGP VT    +V++A+   V   +YD+     H     +P +V+  +  +  
Sbjct: 3   LAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNHDA 62

Query: 399 CLKGGLATP 425
            L G +  P
Sbjct: 63  ILLGAIGDP 71



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>LEU3_MYCBO (P94929) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 336

 Score = 36.2 bits (82), Expect = 0.048
 Identities = 20/69 (28%), Positives = 34/69 (49%), Gaps = 5/69 (7%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDV-----HGDMPAVPPAVIESIPRNKV 398
           + +I GDGIGP VT    +V++A+   V   +YD+     H     +P +V+  +  +  
Sbjct: 3   LAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNHDA 62

Query: 399 CLKGGLATP 425
            L G +  P
Sbjct: 63  ILLGAIGDP 71



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>IDH_RICTY (Q68XA5) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)|
           (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
           ICDH) (IDP)
          Length = 483

 Score = 36.2 bits (82), Expect = 0.048
 Identities = 22/75 (29%), Positives = 33/75 (44%), Gaps = 6/75 (8%)
 Frame = +3

Query: 231 PVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHGDM------PAVPPAVIESIPRN 392
           P+T+  GDGIGP +  AV  ++    A +  ET +V   +        +       I R 
Sbjct: 6   PITIAYGDGIGPEIMDAVLYILRQAEARISLETIEVGEKLYKKHYTSGISEESWNVIQRT 65

Query: 393 KVCLKGGLATPVGGG 437
            + LK  + TP  GG
Sbjct: 66  GIILKAPITTPQSGG 80



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>IDH_ARCFU (O29610) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)|
           (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
           ICDH) (IDP)
          Length = 412

 Score = 36.2 bits (82), Expect = 0.048
 Identities = 26/74 (35%), Positives = 38/74 (51%), Gaps = 11/74 (14%)
 Frame = +3

Query: 249 GDGIGPLVTGAVEQVMEAM-----HAPVYFETY------DVHGDMPAVPPAVIESIPRNK 395
           GDGIG  V  A  +V++A         V+F+ Y       ++G+   +P   + +I   +
Sbjct: 35  GDGIGKDVVPAAIRVLDAAADKIGKEVVWFQVYAGEDAYKLYGNY--LPDDTLNAIKEFR 92

Query: 396 VCLKGGLATPVGGG 437
           V LKG L TPVGGG
Sbjct: 93  VALKGPLTTPVGGG 106



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>LEU3_DEIRA (Q9RTH9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 352

 Score = 35.8 bits (81), Expect = 0.063
 Identities = 21/48 (43%), Positives = 26/48 (54%), Gaps = 7/48 (14%)
 Frame = +3

Query: 225 PRPVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFE-------TYDVHGD 347
           P+ +TL PGDGIGP VT A  QV+  +   V  E        YD HG+
Sbjct: 2   PKVITL-PGDGIGPEVTAAAVQVLREVAPDVTVEEHAIGGGAYDAHGE 48



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>LEU3_MYCPA (Q73VI1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 336

 Score = 34.3 bits (77), Expect = 0.18
 Identities = 21/69 (30%), Positives = 34/69 (49%), Gaps = 5/69 (7%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDV-----HGDMPAVPPAVIESIPRNKV 398
           + +I GDGIGP VT    +V++A+   V    YD+     H     +P +VI+ +  +  
Sbjct: 3   LAVIGGDGIGPEVTAEALKVLDAVLPGVDKTEYDLGARRYHATGELLPDSVIDELRAHDA 62

Query: 399 CLKGGLATP 425
            L G +  P
Sbjct: 63  ILLGAIGDP 71



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>IDH_STRSL (Q59985) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)|
           (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
           ICDH) (IDP)
          Length = 391

 Score = 34.3 bits (77), Expect = 0.18
 Identities = 26/83 (31%), Positives = 37/83 (44%), Gaps = 14/83 (16%)
 Frame = +3

Query: 234 VTLIPGDGIG--------PLVTGAVEQVMEAMHAPVYFE------TYDVHGDMPAVPPAV 371
           +  I GDG+G         +   AVE   E      + E       YD  G+   +P   
Sbjct: 20  IPFIEGDGVGHDIWKNAQAIFDKAVEVAYEGKRHIEWQELLAGKKAYDKTGEW--LPKET 77

Query: 372 IESIPRNKVCLKGGLATPVGGGV 440
           +E+I  + V +KG L TPVGGG+
Sbjct: 78  LEAIRESLVAIKGPLETPVGGGI 100



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>LEU3_CHRVO (Q7NUC2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 354

 Score = 34.3 bits (77), Expect = 0.18
 Identities = 16/47 (34%), Positives = 25/47 (53%), Gaps = 10/47 (21%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVMEAM----------HAPVYFETYDVHG 344
           + ++PGDGIGP +    E+V+E +          HAP+    YD +G
Sbjct: 3   IAILPGDGIGPEIIAQAERVLEVLRRDGLKIETEHAPLGGAAYDQYG 49



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>LEU3_BORPE (Q7VY73) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 358

 Score = 34.3 bits (77), Expect = 0.18
 Identities = 19/66 (28%), Positives = 32/66 (48%), Gaps = 5/66 (7%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHGDM-----PAVPPAVIESIPRNKV 398
           + ++PGDGIGP +    E+V++A+  P+      V G         +PPA +E    +  
Sbjct: 5   IAVLPGDGIGPEIVEQAERVLKALDLPLELRQAPVGGAAFDQFEHPLPPATLELAQGSHA 64

Query: 399 CLKGGL 416
            L G +
Sbjct: 65  VLFGAV 70



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>LEU3_BORPA (Q7W929) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 358

 Score = 34.3 bits (77), Expect = 0.18
 Identities = 19/66 (28%), Positives = 32/66 (48%), Gaps = 5/66 (7%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHGDM-----PAVPPAVIESIPRNKV 398
           + ++PGDGIGP +    E+V++A+  P+      V G         +PPA +E    +  
Sbjct: 5   IAVLPGDGIGPEIVEQAERVLKALDLPLELRQAPVGGAAFDQFEHPLPPATLELAQGSHA 64

Query: 399 CLKGGL 416
            L G +
Sbjct: 65  VLFGAV 70



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>LEU3_BORBR (Q7WKH4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 358

 Score = 34.3 bits (77), Expect = 0.18
 Identities = 19/66 (28%), Positives = 32/66 (48%), Gaps = 5/66 (7%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHGDM-----PAVPPAVIESIPRNKV 398
           + ++PGDGIGP +    E+V++A+  P+      V G         +PPA +E    +  
Sbjct: 5   IAVLPGDGIGPEIVEQAERVLKALDLPLELRQAPVGGAAFDQFEHPLPPATLELAQGSHA 64

Query: 399 CLKGGL 416
            L G +
Sbjct: 65  VLFGAV 70



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>LEU3_SYNPX (Q7U840) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 357

 Score = 33.9 bits (76), Expect = 0.24
 Identities = 15/31 (48%), Positives = 20/31 (64%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFE 326
           V L+PGDGIGP +T    Q++EA+     FE
Sbjct: 6   VVLLPGDGIGPEITAVARQLLEAVSQRHGFE 36



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>IDH_HELPJ (Q9ZN36) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)|
           (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
           ICDH) (IDP)
          Length = 425

 Score = 33.5 bits (75), Expect = 0.31
 Identities = 24/89 (26%), Positives = 40/89 (44%), Gaps = 21/89 (23%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVY-----------------FETYDVHGDMPA-- 356
           +  I GDGIG  +T A+ +V+++     Y                 ++ +  H ++    
Sbjct: 32  IPFIEGDGIGSDITPAMIKVVDSAVQKAYKGEKKIAWYEVFVGEKCYQKFKDHKELSPEE 91

Query: 357 --VPPAVIESIPRNKVCLKGGLATPVGGG 437
             + P  IE+I   KV +KG L TP+G G
Sbjct: 92  QWLLPDTIEAINHYKVSIKGPLTTPIGEG 120



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>IDH_AQUAE (O67480) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)|
           (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
           ICDH) (IDP)
          Length = 426

 Score = 33.1 bits (74), Expect = 0.41
 Identities = 23/81 (28%), Positives = 37/81 (45%), Gaps = 12/81 (14%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVH------GDMPA------VPPAVIE 377
           +  I GDGIGP +T A+  ++       Y  +  ++      GD         +P   ++
Sbjct: 41  IPFIEGDGIGPEITQAMLLIINTAVEKTYNGSKKIYWVELLAGDKAEEKTGERLPQETLD 100

Query: 378 SIPRNKVCLKGGLATPVGGGV 440
            +  + V +KG L TPVG GV
Sbjct: 101 VLKESIVGIKGPLGTPVGKGV 121



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>IDH_HELPY (P56063) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)|
           (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
           ICDH) (IDP)
          Length = 425

 Score = 32.7 bits (73), Expect = 0.53
 Identities = 25/89 (28%), Positives = 40/89 (44%), Gaps = 21/89 (23%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVY--------------------FETY-DVHGDM 350
           +  I GDGIG  +T A+ +V+++     Y                    F+ Y ++  + 
Sbjct: 32  IPFIEGDGIGSDITPAMIKVVDSAVQKAYKGEKKIAWYEVFVGEKCYQKFKDYKELSPEE 91

Query: 351 PAVPPAVIESIPRNKVCLKGGLATPVGGG 437
             + P  IE+I   KV +KG L TP+G G
Sbjct: 92  QWLLPDTIEAINHYKVSIKGPLTTPIGEG 120



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>LRP11_HUMAN (Q86VZ4) Low-density lipoprotein receptor-related protein 11|
           precursor
          Length = 500

 Score = 32.7 bits (73), Expect = 0.53
 Identities = 25/88 (28%), Positives = 38/88 (43%), Gaps = 5/88 (5%)
 Frame = -3

Query: 478 EVELLAELHVREETPPPTGVARPPLRQTLLRGMDSMTAGGT-----AGMSPWTSYVSK*T 314
           E+EL A    +E+ P P       +   ++R  DS+ AG +     A +  W   V+   
Sbjct: 76  ELELRAGGGPQEDCPGPGSGGYSAMPDAIIRTKDSLAAGASFLRAPAAVRGWRQCVA--- 132

Query: 313 GACMASMTCSTAPVTRGPMPSPGMSVTG 230
            AC +   CS A V     P+P  +V G
Sbjct: 133 -ACCSEPRCSVAVVELPRRPAPPAAVLG 159



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>LEU3_PROMT (Q46LE2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 359

 Score = 32.7 bits (73), Expect = 0.53
 Identities = 12/31 (38%), Positives = 20/31 (64%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFE 326
           +TL+PGDGIGP +T    ++++ +     FE
Sbjct: 6   ITLLPGDGIGPEITNVTHKILDLVSRKFGFE 36



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>LEU3_SHIBS (Q326G2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 363

 Score = 32.7 bits (73), Expect = 0.53
 Identities = 22/75 (29%), Positives = 33/75 (44%), Gaps = 11/75 (14%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVMEAM-----------HAPVYFETYDVHGDMPAVPPAVIES 380
           + ++PGDGIGP V     +V++A+           H  V     D HG    +PPA +E 
Sbjct: 7   IAVLPGDGIGPEVMTQALKVLDAVRNRFAMRITTSHYDVGGAAIDNHGQ--PLPPATVEG 64

Query: 381 IPRNKVCLKGGLATP 425
             +    L G +  P
Sbjct: 65  CEQADAVLFGSVGGP 79



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>LEU3_NOCFA (Q5YRX2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 335

 Score = 32.7 bits (73), Expect = 0.53
 Identities = 19/69 (27%), Positives = 32/69 (46%), Gaps = 5/69 (7%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDV-----HGDMPAVPPAVIESIPRNKV 398
           + +IPGDGIGP V     +V++ +   V    YD+     H     +P +V+  +  +  
Sbjct: 3   LAVIPGDGIGPEVIAEALKVLDVVVPGVEKTEYDLGAKRYHATGEILPDSVLPELREHDA 62

Query: 399 CLKGGLATP 425
            L G +  P
Sbjct: 63  ILLGAIGDP 71



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>LEU3_THIDA (Q3SHL3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 353

 Score = 32.7 bits (73), Expect = 0.53
 Identities = 21/74 (28%), Positives = 33/74 (44%), Gaps = 10/74 (13%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMH----------APVYFETYDVHGDMPAVPPAVIESI 383
           + ++PGDGIGP +     +V+EA+           AP+    YD  GD   +P A ++  
Sbjct: 3   IAVLPGDGIGPEIISQAVKVLEALKSEGAKIEMETAPIGGAGYDAAGD--PLPEATLKLA 60

Query: 384 PRNKVCLKGGLATP 425
                 L G +  P
Sbjct: 61  READAVLLGAVGGP 74



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>LEU3_ECOLI (P30125) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 362

 Score = 32.7 bits (73), Expect = 0.53
 Identities = 22/75 (29%), Positives = 33/75 (44%), Gaps = 11/75 (14%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVMEAM-----------HAPVYFETYDVHGDMPAVPPAVIES 380
           + ++PGDGIGP V     +V++A+           H  V     D HG    +PPA +E 
Sbjct: 6   IAVLPGDGIGPEVMTQALKVLDAVRNRFAMRITTSHYDVGGAAIDNHGQ--PLPPATVEG 63

Query: 381 IPRNKVCLKGGLATP 425
             +    L G +  P
Sbjct: 64  CEQADAVLFGSVGGP 78



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>LEU3_ECOL6 (Q8FL76) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 362

 Score = 32.7 bits (73), Expect = 0.53
 Identities = 22/75 (29%), Positives = 33/75 (44%), Gaps = 11/75 (14%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVMEAM-----------HAPVYFETYDVHGDMPAVPPAVIES 380
           + ++PGDGIGP V     +V++A+           H  V     D HG    +PPA +E 
Sbjct: 6   IAVLPGDGIGPEVMTQALKVLDAVRNRFAMRITTSHYDVGGAAIDNHGQ--PLPPATVEG 63

Query: 381 IPRNKVCLKGGLATP 425
             +    L G +  P
Sbjct: 64  CEQADAVLFGSVGGP 78



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>LEU3_ECO57 (Q8X9Z9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 362

 Score = 32.7 bits (73), Expect = 0.53
 Identities = 22/75 (29%), Positives = 33/75 (44%), Gaps = 11/75 (14%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVMEAM-----------HAPVYFETYDVHGDMPAVPPAVIES 380
           + ++PGDGIGP V     +V++A+           H  V     D HG    +PPA +E 
Sbjct: 6   IAVLPGDGIGPEVMTQALKVLDAVRNRFAMRITTSHYDVGGAAIDNHGQ--PLPPATVEG 63

Query: 381 IPRNKVCLKGGLATP 425
             +    L G +  P
Sbjct: 64  CEQADAVLFGSVGGP 78



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>LEU3_CHLTE (P59028) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 352

 Score = 32.3 bits (72), Expect = 0.70
 Identities = 19/50 (38%), Positives = 23/50 (46%), Gaps = 11/50 (22%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFE-----------TYDVHGDM 350
           +  IPGDGIGP V      V+ A+     FE           +YDVHG M
Sbjct: 5   IVSIPGDGIGPEVVAGALDVLNAVAKKHGFEVSVEEHLFGGASYDVHGSM 54



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>RSMB_DROME (Q05856) Small nuclear ribonucleoprotein-associated protein B|
           (snRNP-B) (Sm protein B) (Sm-B) (SmB)
          Length = 199

 Score = 32.3 bits (72), Expect = 0.70
 Identities = 38/128 (29%), Positives = 46/128 (35%), Gaps = 21/128 (16%)
 Frame = -3

Query: 472 ELLAELHVREETPPPTGVARPPLR---------QTLLRGMDSMTAGGTAGMSPWTSYVSK 320
           E +  L V    PP  G+ R P+          +   RGM    +   AG+      V  
Sbjct: 75  ENIVSLTVEGPPPPEEGLPRVPIPGAAPGPGIGRVAGRGMPINLSAVPAGLQGPVRGVG- 133

Query: 319 *TGACMASMTCSTAPVTRGPM---PSPGM---------SVTGRGVPSPGRGM*VTVRRAP 176
             G     M      V R PM   P PGM            GRG P P RG   ++ R  
Sbjct: 134 --GPAQQHMAPMGRGVPRAPMMGAPPPGMIPGGMPSMPGNMGRGAPPPMRGPPPSMIRGA 191

Query: 175 PPWPGRDG 152
           PP PGR G
Sbjct: 192 PP-PGRGG 198



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>LEU3_ARCFU (O29627) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 326

 Score = 32.3 bits (72), Expect = 0.70
 Identities = 18/66 (27%), Positives = 31/66 (46%), Gaps = 5/66 (7%)
 Frame = +3

Query: 228 RPVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHGDM-----PAVPPAVIESIPRN 392
           + + +IPGDGIG  V  A   ++E +  P  +  YD   +       A+P   +E+  ++
Sbjct: 2   KKIVVIPGDGIGKEVMEAAMLILEKLDLPFEYSYYDAGDEALEKYGKALPDETLEACRKS 61

Query: 393 KVCLKG 410
              L G
Sbjct: 62  DAVLFG 67



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>LEU3_AGRT5 (P24404) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 370

 Score = 32.3 bits (72), Expect = 0.70
 Identities = 26/84 (30%), Positives = 36/84 (42%), Gaps = 11/84 (13%)
 Frame = +3

Query: 222 TPRPVTLIPGDGIGPLVTGAVEQVMEAMHAP-----------VYFETYDVHGDMPAVPPA 368
           T R + L+PGDGIGP     V +++E M++            V    YD HG   A+  A
Sbjct: 2   TVRSLFLLPGDGIGPEAMTEVRKLIEYMNSAHNAGFTVSEGLVGGSAYDAHG--VAISDA 59

Query: 369 VIESIPRNKVCLKGGLATPVGGGV 440
            +E        L G +  P   GV
Sbjct: 60  DMEKALAADAILFGAVGGPKWDGV 83



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>DLPA_LEGPH (Q48806) Protein dlpA|
          Length = 615

 Score = 32.0 bits (71), Expect = 0.91
 Identities = 20/71 (28%), Positives = 31/71 (43%), Gaps = 5/71 (7%)
 Frame = +3

Query: 225 PRPVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHGDM-----PAVPPAVIESIPR 389
           P  + ++PGDGIG  VT A   V E +  PV     D+  +       A+P    + I  
Sbjct: 6   PIKIAVLPGDGIGIEVTEATLPVFEVLDVPVILNYGDIGWEFWKKEGAAIPSRTWQLIAS 65

Query: 390 NKVCLKGGLAT 422
           +   L G + +
Sbjct: 66  SDTVLLGAITS 76



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>LEU3_SHISS (Q3Z5T7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 363

 Score = 32.0 bits (71), Expect = 0.91
 Identities = 22/75 (29%), Positives = 32/75 (42%), Gaps = 11/75 (14%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVMEAM-----------HAPVYFETYDVHGDMPAVPPAVIES 380
           + ++PGDGIGP V     +V+ A+           H  V     D HG    +PPA +E 
Sbjct: 7   IAVLPGDGIGPEVMTQALKVLNAVRNRFAMRITTSHYDVGGAAIDNHGQ--PLPPATVEG 64

Query: 381 IPRNKVCLKGGLATP 425
             +    L G +  P
Sbjct: 65  CEQADAVLFGSVGGP 79



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>LEU3_SHIDS (Q32K21) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 363

 Score = 32.0 bits (71), Expect = 0.91
 Identities = 22/75 (29%), Positives = 32/75 (42%), Gaps = 11/75 (14%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVMEAM-----------HAPVYFETYDVHGDMPAVPPAVIES 380
           +  +PGDGIGP V     +V++A+           H  V     D HG    +PPA +E 
Sbjct: 7   IAALPGDGIGPEVMTQALKVLDAVRNRFAMRITTSHYDVGGAAIDNHGQ--PLPPATVEG 64

Query: 381 IPRNKVCLKGGLATP 425
             +    L G +  P
Sbjct: 65  CEQADAVLFGSVGGP 79



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>MYO15_HUMAN (Q9UKN7) Myosin-15 (Myosin XV) (Unconventional myosin-15)|
          Length = 3530

 Score = 32.0 bits (71), Expect = 0.91
 Identities = 15/37 (40%), Positives = 21/37 (56%)
 Frame = -3

Query: 277 PVTRGPMPSPGMSVTGRGVPSPGRGM*VTVRRAPPPW 167
           P + GP P+P +S    G+P P      ++RR PPPW
Sbjct: 669 PPSSGPPPAPPLSPALSGLPRPASPY-GSLRRHPPPW 704



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>LEU3_PSEHT (Q3IJS3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 358

 Score = 32.0 bits (71), Expect = 0.91
 Identities = 21/75 (28%), Positives = 33/75 (44%), Gaps = 11/75 (14%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVMEAM-----------HAPVYFETYDVHGDMPAVPPAVIES 380
           V ++ GDGIGP +  A EQV++A+           H  +     D HG   A+P + + +
Sbjct: 8   VAVLAGDGIGPEIMAAAEQVLDAVSNKFGFTLNREHHAIGGAAIDKHG--KALPQSTVTA 65

Query: 381 IPRNKVCLKGGLATP 425
                  L G +  P
Sbjct: 66  CENADAILFGAVGGP 80



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>LEU3_SHIFL (Q83SP1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 362

 Score = 32.0 bits (71), Expect = 0.91
 Identities = 22/75 (29%), Positives = 32/75 (42%), Gaps = 11/75 (14%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVMEAM-----------HAPVYFETYDVHGDMPAVPPAVIES 380
           + ++PGDGIGP V     +V+ A+           H  V     D HG    +PPA +E 
Sbjct: 6   IAVLPGDGIGPEVMTQALKVLNAVRNRFAMRITTSHYDVGGAAIDNHGQ--PLPPATVEG 63

Query: 381 IPRNKVCLKGGLATP 425
             +    L G +  P
Sbjct: 64  CEQADAVLFGSVGGP 78



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>IDH_STRMU (Q59940) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)|
           (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
           ICDH) (IDP)
          Length = 393

 Score = 31.6 bits (70), Expect = 1.2
 Identities = 23/83 (27%), Positives = 37/83 (44%), Gaps = 14/83 (16%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYF--------------ETYDVHGDMPAVPPAV 371
           +  I GDG+G  +    + V +   A VY               + Y+  G+   +P   
Sbjct: 20  IPYIEGDGVGQDIWKNAQIVFDKAIAKVYGGHKQVIWREVLAGKKAYNETGNW--LPNET 77

Query: 372 IESIPRNKVCLKGGLATPVGGGV 440
           +E I  + + +KG L TPVGGG+
Sbjct: 78  LEIIKTHLLAIKGPLETPVGGGI 100



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>LEU3_MYCLE (O33117) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 336

 Score = 31.6 bits (70), Expect = 1.2
 Identities = 18/69 (26%), Positives = 32/69 (46%), Gaps = 5/69 (7%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDV-----HGDMPAVPPAVIESIPRNKV 398
           + +I GDGIGP V     ++++ +   V   TYD+     H     +P +V+  +  +  
Sbjct: 3   LAIIGGDGIGPEVVAQAVKILDVVLPGVQKTTYDLGARRYHTTGELLPESVLAELREHDA 62

Query: 399 CLKGGLATP 425
            L G +  P
Sbjct: 63  ILLGAVGDP 71



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>LEU3_PHACH (O59930) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 380

 Score = 31.6 bits (70), Expect = 1.2
 Identities = 23/77 (29%), Positives = 34/77 (44%), Gaps = 10/77 (12%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHA-----PVYFETYDVHG---DMPAVP--PAVIESI 383
           + ++PGDGIGP V     +V+E + A      +  ET+D  G   D    P   A +E+ 
Sbjct: 8   IVILPGDGIGPEVVAEATRVLEVVSASSSDVEIKLETHDFGGCSIDKHGEPLTAATLEAC 67

Query: 384 PRNKVCLKGGLATPVGG 434
                 L G +  P  G
Sbjct: 68  KLADAILLGAIGGPKWG 84



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>LEU3_BACHD (Q9K8E9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 363

 Score = 31.6 bits (70), Expect = 1.2
 Identities = 12/26 (46%), Positives = 20/26 (76%)
 Frame = +3

Query: 228 RPVTLIPGDGIGPLVTGAVEQVMEAM 305
           + + ++PGDGIGP VT A  +V++A+
Sbjct: 3   KQIAVLPGDGIGPEVTDAAIEVLQAV 28



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>LEU3_THEFY (Q47SB4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 354

 Score = 31.6 bits (70), Expect = 1.2
 Identities = 23/74 (31%), Positives = 34/74 (45%), Gaps = 10/74 (13%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDV----------HGDMPAVPPAVIESI 383
           + +IPGDGIGP V     +V+ A+ AP +  T D           H     +P AV E +
Sbjct: 8   LAVIPGDGIGPEVVAEGLKVLSAV-APRHGLTLDTTEYELGAQRWHATGEVLPDAVEEEL 66

Query: 384 PRNKVCLKGGLATP 425
            ++   L G +  P
Sbjct: 67  RQHDAILLGAVGDP 80



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>LEU3_SALTY (P37412) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 363

 Score = 31.2 bits (69), Expect = 1.6
 Identities = 19/73 (26%), Positives = 31/73 (42%), Gaps = 9/73 (12%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHGDMPAV---------PPAVIESIP 386
           + ++PGDGIGP V     +VM+A+ +         H D+  +         P A +E   
Sbjct: 7   IAVLPGDGIGPEVMAQALKVMDAVRSRFDMRITTSHYDVGGIAIDNHGHPLPKATVEGCE 66

Query: 387 RNKVCLKGGLATP 425
           +    L G +  P
Sbjct: 67  QADAILFGSVGGP 79



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>LEU3_SALCH (Q57TE7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 363

 Score = 31.2 bits (69), Expect = 1.6
 Identities = 19/73 (26%), Positives = 31/73 (42%), Gaps = 9/73 (12%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHGDMPAV---------PPAVIESIP 386
           + ++PGDGIGP V     +VM+A+ +         H D+  +         P A +E   
Sbjct: 7   IAVLPGDGIGPEVMAQALKVMDAVRSRFDMRITTSHYDVGGIAIDNHGHPLPKATVEGCE 66

Query: 387 RNKVCLKGGLATP 425
           +    L G +  P
Sbjct: 67  QADAILFGSVGGP 79



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>LEU3_ACIAD (Q6FEV6) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 359

 Score = 31.2 bits (69), Expect = 1.6
 Identities = 20/77 (25%), Positives = 31/77 (40%), Gaps = 11/77 (14%)
 Frame = +3

Query: 228 RPVTLIPGDGIGPLVTGAVEQVMEAM-----------HAPVYFETYDVHGDMPAVPPAVI 374
           + + ++ GDGIGP + GA EQV+  +           H  +     D HG+    P    
Sbjct: 3   KQILILAGDGIGPEIVGAAEQVLTKVNEKFELGLTWEHGLLGGSAIDAHGE--PYPAVTS 60

Query: 375 ESIPRNKVCLKGGLATP 425
           E   +    L G +  P
Sbjct: 61  EQAKKADAILLGAVGGP 77



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>KDSB_VIBCH (Q9KQX2) 3-deoxy-manno-octulosonate cytidylyltransferase (EC|
           2.7.7.38) (CMP-KDO synthetase)
           (CMP-2-keto-3-deoxyoctulosonic acid synthetase) (CKS)
          Length = 252

 Score = 31.2 bits (69), Expect = 1.6
 Identities = 15/50 (30%), Positives = 23/50 (46%)
 Frame = +3

Query: 273 TGAVEQVMEAMHAPVYFETYDVHGDMPAVPPAVIESIPRNKVCLKGGLAT 422
           T  + +V+  M  P      +V GD P +PPA+I  +  N       +AT
Sbjct: 76  TERLAEVVAKMAIPADHIVVNVQGDEPLIPPAIIRQVADNLAACSAPMAT 125



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>WASP_MOUSE (P70315) Wiskott-Aldrich syndrome protein homolog (WASp)|
          Length = 520

 Score = 31.2 bits (69), Expect = 1.6
 Identities = 32/103 (31%), Positives = 37/103 (35%)
 Frame = -3

Query: 460 ELHVREETPPPTGVARPPLRQTLLRGMDSMTAGGTAGMSPWTSYVSK*TGACMASMTCST 281
           E+  +E  PPP     PP R     G      GG  G  P    V       + S    +
Sbjct: 308 EMRRQEPLPPPP----PPCRGGGGGGGGGGGGGGGGGGQPLRPPV-------VGSNKGRS 356

Query: 280 APVTRGPMPSPGMSVTGRGVPSPGRGM*VTVRRAPPPWPGRDG 152
            P+   PM       T RG P PGRG        PPP  GR G
Sbjct: 357 GPLPPVPMGGAPPPPTPRGPPPPGRG---GPPPPPPPATGRSG 396



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>LEU3_BRUSU (Q8FVF3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 370

 Score = 31.2 bits (69), Expect = 1.6
 Identities = 24/77 (31%), Positives = 35/77 (45%), Gaps = 11/77 (14%)
 Frame = +3

Query: 228 RPVTLIPGDGIGPLVTGAVEQVMEAMHAPVY--FET---------YDVHGDMPAVPPAVI 374
           R + L+PGDGIGP     V +V+  +++ +   FET         YD HG   A+  A +
Sbjct: 4   RKLLLLPGDGIGPEAMAEVRKVIAFLNSDLNLGFETEEGLVGGCAYDAHGQ--AISDADM 61

Query: 375 ESIPRNKVCLKGGLATP 425
           E        L G +  P
Sbjct: 62  EKALAADAVLFGAVGGP 78



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>LEU3_BRUME (Q8YCX4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 370

 Score = 31.2 bits (69), Expect = 1.6
 Identities = 24/77 (31%), Positives = 35/77 (45%), Gaps = 11/77 (14%)
 Frame = +3

Query: 228 RPVTLIPGDGIGPLVTGAVEQVMEAMHAPVY--FET---------YDVHGDMPAVPPAVI 374
           R + L+PGDGIGP     V +V+  +++ +   FET         YD HG   A+  A +
Sbjct: 4   RKLLLLPGDGIGPEAMAEVRKVIAFLNSDLNLGFETEEGLVGGCAYDAHGQ--AISDADM 61

Query: 375 ESIPRNKVCLKGGLATP 425
           E        L G +  P
Sbjct: 62  EKALAADAVLFGAVGGP 78



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>KDSB_VIBPA (Q87R14) 3-deoxy-manno-octulosonate cytidylyltransferase (EC|
           2.7.7.38) (CMP-KDO synthetase)
           (CMP-2-keto-3-deoxyoctulosonic acid synthetase) (CKS)
          Length = 251

 Score = 31.2 bits (69), Expect = 1.6
 Identities = 16/50 (32%), Positives = 23/50 (46%)
 Frame = +3

Query: 273 TGAVEQVMEAMHAPVYFETYDVHGDMPAVPPAVIESIPRNKVCLKGGLAT 422
           T  + +V+E M  P      +V GD P VPP +I  +  N       +AT
Sbjct: 76  TERLAEVVEKMAIPADHIIVNVQGDEPLVPPVIIRQVADNLAASDAPMAT 125



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>LEU3_THEAQ (P24098) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 344

 Score = 30.8 bits (68), Expect = 2.0
 Identities = 13/24 (54%), Positives = 19/24 (79%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVMEAM 305
           V ++PGDGIGP VT A  +V++A+
Sbjct: 3   VAVLPGDGIGPEVTEAALRVLKAL 26



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>LEU3_SALTI (Q8Z9I1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 363

 Score = 30.8 bits (68), Expect = 2.0
 Identities = 21/73 (28%), Positives = 33/73 (45%), Gaps = 9/73 (12%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHA----PVYFETYDVHG-----DMPAVPPAVIESIP 386
           + ++PGDGIGP V     +VM+A+ +     +    YDV G         +P A +E   
Sbjct: 7   IAVLPGDGIGPEVMAQALKVMDAVRSRFDMRITTSRYDVGGIAIDNHGHPLPKATVEGCE 66

Query: 387 RNKVCLKGGLATP 425
           +    L G +  P
Sbjct: 67  QADAILFGSVGGP 79



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>LEU3_SALPA (Q5PDG2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 363

 Score = 30.8 bits (68), Expect = 2.0
 Identities = 21/73 (28%), Positives = 33/73 (45%), Gaps = 9/73 (12%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHA----PVYFETYDVHG-----DMPAVPPAVIESIP 386
           + ++PGDGIGP V     +VM+A+ +     +    YDV G         +P A +E   
Sbjct: 7   IAVLPGDGIGPEVMAQALKVMDAVRSRFDMRITTSRYDVGGIAIDNHGHPLPKATVEGCE 66

Query: 387 RNKVCLKGGLATP 425
           +    L G +  P
Sbjct: 67  QADAILFGSVGGP 79



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>NMDE3_HUMAN (Q14957) Glutamate [NMDA] receptor subunit epsilon 3 precursor|
            (N-methyl D-aspartate receptor subtype 2C) (NR2C)
            (NMDAR2C)
          Length = 1233

 Score = 30.8 bits (68), Expect = 2.0
 Identities = 20/41 (48%), Positives = 21/41 (51%)
 Frame = -3

Query: 280  APVTRGPMPSPGMSVTGRGVPSPGRGM*VTVRRAPPPWPGR 158
            +P    P P P  S TG G P  GR     VRRAP P PGR
Sbjct: 943  SPCLPTPDPPPEPSPTGWGPPDGGRA--ALVRRAPQP-PGR 980



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>LEU3_THETH (P61495) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 345

 Score = 30.4 bits (67), Expect = 2.7
 Identities = 13/24 (54%), Positives = 18/24 (75%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVMEAM 305
           V ++PGDGIGP VT A  +V+ A+
Sbjct: 3   VAVLPGDGIGPEVTEAALKVLRAL 26



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>LEU3_THET8 (Q5SIY4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 345

 Score = 30.4 bits (67), Expect = 2.7
 Identities = 13/24 (54%), Positives = 18/24 (75%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVMEAM 305
           V ++PGDGIGP VT A  +V+ A+
Sbjct: 3   VAVLPGDGIGPEVTEAALKVLRAL 26



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>LEU3_THET2 (P61494) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 345

 Score = 30.4 bits (67), Expect = 2.7
 Identities = 13/24 (54%), Positives = 18/24 (75%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVMEAM 305
           V ++PGDGIGP VT A  +V+ A+
Sbjct: 3   VAVLPGDGIGPEVTEAALKVLRAL 26



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>LEU3_PROMM (Q7V842) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 357

 Score = 30.4 bits (67), Expect = 2.7
 Identities = 18/73 (24%), Positives = 36/73 (49%), Gaps = 9/73 (12%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVMEAM---HA-PVYFETYDVHG-----DMPAVPPAVIESIP 386
           + L+PGDGIGP +T   + +++A+   H   + FE + + G         +P + +E+  
Sbjct: 6   IVLLPGDGIGPEITAVAKLLLDALGHQHGFKLNFEQHPIGGVAIDASGSPLPASTLEACQ 65

Query: 387 RNKVCLKGGLATP 425
            +   L   + +P
Sbjct: 66  ASDAVLLAAIGSP 78



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>SPN90_HUMAN (Q9NZQ3) SH3 adapter protein SPIN90 (NCK-interacting protein with|
           SH3 domain) (SH3 protein interacting with Nck, 90 kDa)
           (VacA-interacting protein, 54 kDa) (VIP54) (AF3p21)
           (Diaphanous protein-interacting protein)
           (Dia-interacting protein 1)
          Length = 722

 Score = 30.4 bits (67), Expect = 2.7
 Identities = 24/90 (26%), Positives = 36/90 (40%)
 Frame = -3

Query: 439 TPPPTGVARPPLRQTLLRGMDSMTAGGTAGMSPWTSYVSK*TGACMASMTCSTAPVTRGP 260
           TPPP      P+++   R  +++ A G+ G +   S  +  +     S T      T   
Sbjct: 181 TPPP------PVKR---RDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDTLYTSSS 231

Query: 259 MPSPGMSVTGRGVPSPGRGM*VTVRRAPPP 170
              PG S +    P P RG   TV +  PP
Sbjct: 232 PSEPGSSCSPTPPPVPRRGTHTTVSQVQPP 261



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>LEU3_RALEJ (Q46YW0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 355

 Score = 30.4 bits (67), Expect = 2.7
 Identities = 13/37 (35%), Positives = 20/37 (54%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHG 344
           + ++PGDGIGP +     +V+ A+      ET  V G
Sbjct: 3   IAVLPGDGIGPEIVAEAVKVLNALDEKFEMETAPVGG 39



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>LEU3_AZOSE (Q5P1J6) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 350

 Score = 30.4 bits (67), Expect = 2.7
 Identities = 11/24 (45%), Positives = 18/24 (75%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVMEAM 305
           + ++PGDGIGP +T    +V+EA+
Sbjct: 3   ICILPGDGIGPEITAEAVRVIEAL 26



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>TTUC5_AGRVI (O34295) Probable tartrate dehydrogenase/decarboxylase ttuC' (EC|
           1.1.1.93) (EC 4.1.1.73) (TDH) (D-malate dehydrogenase
           [decarboxylating]) (EC 1.1.1.83)
          Length = 358

 Score = 30.4 bits (67), Expect = 2.7
 Identities = 17/43 (39%), Positives = 23/43 (53%), Gaps = 5/43 (11%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHA-----PVYFETYDVHGD 347
           +  IP DGIGP V  A  QV+EA+        ++ ET+D   D
Sbjct: 6   IAAIPADGIGPEVIAAGLQVLEALEQRSGDFKIHTETFDWGSD 48



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>TTUC4_AGRVI (P70792) Probable tartrate dehydrogenase/decarboxylase ttuC' (EC|
           1.1.1.93) (EC 4.1.1.73) (TDH) (D-malate dehydrogenase
           [decarboxylating]) (EC 1.1.1.83)
          Length = 358

 Score = 30.4 bits (67), Expect = 2.7
 Identities = 17/43 (39%), Positives = 23/43 (53%), Gaps = 5/43 (11%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHA-----PVYFETYDVHGD 347
           +  IP DGIGP V  A  QV+EA+        ++ ET+D   D
Sbjct: 6   IAAIPADGIGPEVIAAGLQVLEALEKRSGDFSIHTETFDWGSD 48



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>TTUC3_AGRVI (O34296) Probable tartrate dehydrogenase/decarboxylase ttuC' (EC|
           1.1.1.93) (EC 4.1.1.73) (TDH) (D-malate dehydrogenase
           [decarboxylating]) (EC 1.1.1.83)
          Length = 358

 Score = 30.4 bits (67), Expect = 2.7
 Identities = 17/43 (39%), Positives = 23/43 (53%), Gaps = 5/43 (11%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHA-----PVYFETYDVHGD 347
           +  IP DGIGP V  A  QV+EA+        ++ ET+D   D
Sbjct: 6   IAAIPADGIGPEVIAAGLQVLEALEQRSGDFKIHTETFDWGSD 48



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>TTUC2_AGRVI (P70787) Probable tartrate dehydrogenase/decarboxylase ttuC (EC|
           1.1.1.93) (EC 4.1.1.73) (TDH) (D-malate dehydrogenase
           [decarboxylating]) (EC 1.1.1.83)
          Length = 364

 Score = 30.4 bits (67), Expect = 2.7
 Identities = 17/43 (39%), Positives = 23/43 (53%), Gaps = 5/43 (11%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHA-----PVYFETYDVHGD 347
           +  IP DGIGP V  A  QV+EA+        ++ ET+D   D
Sbjct: 6   IAAIPADGIGPEVIAAGLQVLEALEKRSGDFSIHTETFDWGSD 48



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>TTUC1_AGRVI (Q44471) Probable tartrate dehydrogenase/decarboxylase ttuC (EC|
           1.1.1.93) (EC 4.1.1.73) (TDH) (D-malate dehydrogenase
           [decarboxylating]) (EC 1.1.1.83)
          Length = 364

 Score = 30.4 bits (67), Expect = 2.7
 Identities = 17/43 (39%), Positives = 23/43 (53%), Gaps = 5/43 (11%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHA-----PVYFETYDVHGD 347
           +  IP DGIGP V  A  QV+EA+        ++ ET+D   D
Sbjct: 6   IAAIPADGIGPEVIAAGLQVLEALEQRSGDFKIHTETFDWGSD 48



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>LEU3_BACSK (Q5WEN4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 364

 Score = 30.4 bits (67), Expect = 2.7
 Identities = 13/35 (37%), Positives = 23/35 (65%)
 Frame = +3

Query: 228 RPVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETY 332
           + + L+PGDGIGP +    ++V+E + A +Y  T+
Sbjct: 3   KQILLLPGDGIGPEIIAETKRVLEEI-ARLYHHTF 36



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>IDH3B_PIG (P56472) Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial|
           (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific
           ICDH) (Fragments)
          Length = 103

 Score = 30.0 bits (66), Expect = 3.5
 Identities = 11/18 (61%), Positives = 15/18 (83%)
 Frame = +3

Query: 231 PVTLIPGDGIGPLVTGAV 284
           PVT++PGDG+GP +  AV
Sbjct: 16  PVTMLPGDGVGPELMAAV 33



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>FBX41_HUMAN (Q8TF61) F-box only protein 41|
          Length = 874

 Score = 30.0 bits (66), Expect = 3.5
 Identities = 14/31 (45%), Positives = 16/31 (51%)
 Frame = -3

Query: 304 MASMTCSTAPVTRGPMPSPGMSVTGRGVPSP 212
           +AS  CST P   GP P PG +      PSP
Sbjct: 162 VASSACSTPPPGPGPGPCPGPASASPASPSP 192



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>CSKI1_HUMAN (Q8WXD9) Caskin-1 (CASK-interacting protein 1)|
          Length = 1431

 Score = 30.0 bits (66), Expect = 3.5
 Identities = 29/104 (27%), Positives = 36/104 (34%), Gaps = 9/104 (8%)
 Frame = -3

Query: 448  REETPPPTGVARPPLRQTLLRGMDSMTAGGTAGMSPWTSYVS------K*TGACMASMTC 287
            R+  PP T    PP   T  R       GG  G +P T+ V         T   M+  + 
Sbjct: 764  RQVLPPGTSHFTPPQTPTKTRPGSPQALGGPHGPAPATAKVKPTPQLLPPTERPMSPRSL 823

Query: 286  STAPVTRG---PMPSPGMSVTGRGVPSPGRGM*VTVRRAPPPWP 164
              +P  RG    +P P     G   P P          APPP P
Sbjct: 824  PQSPTHRGFAYVLPQPVEGEVGPAAPGP----------APPPVP 857



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>SENP3_HUMAN (Q9H4L4) Sentrin-specific protease 3 (EC 3.4.22.-)|
           (Sentrin/SUMO-specific protease SENP3) (SUMO-1-specific
           protease 3)
          Length = 574

 Score = 30.0 bits (66), Expect = 3.5
 Identities = 15/38 (39%), Positives = 17/38 (44%)
 Frame = -3

Query: 262 PMPSPGMSVTGRGVPSPGRGM*VTVRRAPPPWPGRDGA 149
           P P P +   G   P PG G  V  RR P P P  D +
Sbjct: 36  PPPKPRLKSGGGFGPDPGSGTTVPTRRLPAPRPSFDAS 73



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>LEU3_RHIME (Q92KY8) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 370

 Score = 30.0 bits (66), Expect = 3.5
 Identities = 18/52 (34%), Positives = 24/52 (46%), Gaps = 11/52 (21%)
 Frame = +3

Query: 222 TPRPVTLIPGDGIGPLVTGAVEQVMEAMHAP-----------VYFETYDVHG 344
           T R + L+PGDGIGP     V +++  M+A            V    YD HG
Sbjct: 2   TVRNLFLLPGDGIGPEAMAEVRKIIAYMNAERDAGFVTDEGLVGGSAYDAHG 53



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>LEU3_CAUCR (Q9ABN3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 350

 Score = 30.0 bits (66), Expect = 3.5
 Identities = 16/42 (38%), Positives = 22/42 (52%), Gaps = 7/42 (16%)
 Frame = +3

Query: 240 LIPGDGIGPLVTGAVEQVMEAMHAPVYFE-------TYDVHG 344
           L+PGDGIGP V   V +V  A+   +  +       +YD HG
Sbjct: 6   LLPGDGIGPEVCAQVRRVAAALTPDLKVDEALYGGASYDTHG 47



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>Y1617_METMA (Q8PWH0) UPF0272 protein MM1617|
          Length = 396

 Score = 30.0 bits (66), Expect = 3.5
 Identities = 14/39 (35%), Positives = 20/39 (51%), Gaps = 5/39 (12%)
 Frame = +3

Query: 339 HGDMPAVPPAVIESIPRNKVCLKGG-----LATPVGGGV 440
           HG +P   PA +E + R K+  +GG     L TP G  +
Sbjct: 159 HGTLPVPAPATLEILRRGKLYFRGGNVNKELLTPTGAAI 197



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>KDSB_YERPE (Q8ZGA4) 3-deoxy-manno-octulosonate cytidylyltransferase (EC|
           2.7.7.38) (CMP-KDO synthetase)
           (CMP-2-keto-3-deoxyoctulosonic acid synthetase) (CKS)
          Length = 250

 Score = 30.0 bits (66), Expect = 3.5
 Identities = 12/30 (40%), Positives = 16/30 (53%)
 Frame = +3

Query: 333 DVHGDMPAVPPAVIESIPRNKVCLKGGLAT 422
           +V GD P VPP +I  +  N      G+AT
Sbjct: 96  NVQGDEPLVPPVIIRQVADNLAACSAGMAT 125



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>LEU31_ARATH (Q9SA14) 3-isopropylmalate dehydrogenase 1, chloroplast precursor|
           (EC 1.1.1.85) (Beta-IPM dehydrogenase 1) (IMDH 1)
           (3-IPM-DH 1)
          Length = 406

 Score = 29.6 bits (65), Expect = 4.5
 Identities = 11/22 (50%), Positives = 16/22 (72%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVME 299
           +TL+PGDGIGP V    + V++
Sbjct: 46  ITLLPGDGIGPEVISVAKNVLQ 67



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>LEU3_VIBVY (Q7MP78) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 363

 Score = 29.6 bits (65), Expect = 4.5
 Identities = 17/42 (40%), Positives = 27/42 (64%), Gaps = 5/42 (11%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVMEAM---HAPVYF--ETYDVHG 344
           + ++PGDGIGP V     +V++A+   HA ++F  E +DV G
Sbjct: 8   IAVLPGDGIGPEVMAQAHKVLDAIEKKHA-IHFEREEHDVGG 48



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>LEU3_VIBVU (Q8DEE0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 363

 Score = 29.6 bits (65), Expect = 4.5
 Identities = 17/42 (40%), Positives = 27/42 (64%), Gaps = 5/42 (11%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVMEAM---HAPVYF--ETYDVHG 344
           + ++PGDGIGP V     +V++A+   HA ++F  E +DV G
Sbjct: 8   IAVLPGDGIGPEVMAQAHKVLDAIEKKHA-IHFEREEHDVGG 48



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>LEU3_BRAJA (Q89X19) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 370

 Score = 29.6 bits (65), Expect = 4.5
 Identities = 17/45 (37%), Positives = 26/45 (57%), Gaps = 11/45 (24%)
 Frame = +3

Query: 240 LIPGDGIGPLVTGAVEQVMEAMHAP--VYFET---------YDVH 341
           L+PGDGIGP V G V+++++ +++     FET         YD H
Sbjct: 8   LLPGDGIGPEVMGEVKRLIDWLNSAGIAKFETDTGLVGGSAYDAH 52



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>LEU32_ARATH (P93832) 3-isopropylmalate dehydrogenase 2, chloroplast precursor|
           (EC 1.1.1.85) (Beta-IPM dehydrogenase 2) (IMDH 2)
           (3-IPM-DH 2)
          Length = 405

 Score = 29.6 bits (65), Expect = 4.5
 Identities = 11/22 (50%), Positives = 16/22 (72%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVME 299
           +TL+PGDGIGP V    + V++
Sbjct: 45  ITLLPGDGIGPEVVSIAKNVLQ 66



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>CENG1_HUMAN (Q99490) Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like,|
           ankyrin repeat and pleckstrin homology domains 2)
           (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE)
           (GTP-binding and GTPase activating protein 2) (GGAP2)
          Length = 1192

 Score = 29.6 bits (65), Expect = 4.5
 Identities = 16/42 (38%), Positives = 20/42 (47%)
 Frame = -3

Query: 286 STAPVTRGPMPSPGMSVTGRGVPSPGRGM*VTVRRAPPPWPG 161
           S  P+T  P PSP  +VT      PG    +T+    PP PG
Sbjct: 289 SPPPLTLPPTPSPATAVTAASAQPPGPAPPITLE---PPAPG 327



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>LEU3_METCA (Q606F4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 360

 Score = 29.6 bits (65), Expect = 4.5
 Identities = 14/48 (29%), Positives = 23/48 (47%), Gaps = 11/48 (22%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVMEAM-----------HAPVYFETYDVHG 344
           + ++PGDGIGP +     +V++ +           HA +    YD HG
Sbjct: 5   IAVLPGDGIGPEIVAEALKVLDCLRSDFGLAVETEHALIGGAAYDAHG 52



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>LEU3_BRANA (P29102) 3-isopropylmalate dehydrogenase, chloroplast precursor (EC|
           1.1.1.85) (Beta-IPM dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 406

 Score = 29.3 bits (64), Expect = 5.9
 Identities = 11/22 (50%), Positives = 16/22 (72%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVME 299
           +TL+PGDGIGP V    + V++
Sbjct: 46  ITLLPGDGIGPEVISIAKNVLQ 67



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>LEU3_YERPS (Q66EM2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 363

 Score = 29.3 bits (64), Expect = 5.9
 Identities = 14/41 (34%), Positives = 22/41 (53%), Gaps = 4/41 (9%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMH----APVYFETYDVHG 344
           + ++PGDGIGP V     +V++A+       +    YDV G
Sbjct: 7   IAVLPGDGIGPEVMAQASKVLDAVRQRFGLKISTSVYDVGG 47



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>LEU3_YERPE (Q8ZIG9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 363

 Score = 29.3 bits (64), Expect = 5.9
 Identities = 14/41 (34%), Positives = 22/41 (53%), Gaps = 4/41 (9%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMH----APVYFETYDVHG 344
           + ++PGDGIGP V     +V++A+       +    YDV G
Sbjct: 7   IAVLPGDGIGPEVMAQASKVLDAVRQRFGLKISTSVYDVGG 47



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>HSLU_AQUAE (O66574) ATP-dependent hsl protease ATP-binding subunit hslU|
          Length = 450

 Score = 29.3 bits (64), Expect = 5.9
 Identities = 14/41 (34%), Positives = 23/41 (56%)
 Frame = -3

Query: 484 GEEVELLAELHVREETPPPTGVARPPLRQTLLRGMDSMTAG 362
           GE  + + E+ V+E+T P  G+A PP  + L   +  M +G
Sbjct: 173 GELDDRIVEIEVKEKTVPMVGIAGPPGLEELENQIKEMLSG 213



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>MUCDL_RAT (Q9JIK1) Mucin and cadherin-like protein precursor|
           (Mu-protocadherin) (GP100)
          Length = 862

 Score = 29.3 bits (64), Expect = 5.9
 Identities = 20/78 (25%), Positives = 31/78 (39%)
 Frame = -3

Query: 466 LAELHVREETPPPTGVARPPLRQTLLRGMDSMTAGGTAGMSPWTSYVSK*TGACMASMTC 287
           + E+ V E  PP T    PP             AGGT G S  T+  +  T         
Sbjct: 449 IVEIQVSEREPPSTESPTPP------------EAGGTTGPSSNTTLETPSTSGTSQGPAT 496

Query: 286 STAPVTRGPMPSPGMSVT 233
           +++  + GP P  G +++
Sbjct: 497 TSSGGSAGPFPPAGTTLS 514



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>MUC2_RAT (Q62635) Mucin-2 precursor (Intestinal mucin 2) (Fragment)|
          Length = 1513

 Score = 29.3 bits (64), Expect = 5.9
 Identities = 23/78 (29%), Positives = 33/78 (42%), Gaps = 2/78 (2%)
 Frame = -3

Query: 439  TPPPTGVARPPLRQTLLRGMDSMTAGGTAGMSPWTSYVSK*TGACMASMTCSTAPV--TR 266
            T P T  A  P    +   +   T+  T+  SP TS  +  T    ++ + + +P   T 
Sbjct: 1415 TSPLTSSATSPTTSHITSTVSPTTSPTTSTTSPTTSPTTSTTSPTTSTTSPTPSPTTSTT 1474

Query: 265  GPMPSPGMSVTGRGVPSP 212
             P PSP  S T    PSP
Sbjct: 1475 SPTPSPTTSTTS-PTPSP 1491



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>LEU3_PELCD (Q3A3B2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 365

 Score = 29.3 bits (64), Expect = 5.9
 Identities = 20/73 (27%), Positives = 33/73 (45%), Gaps = 9/73 (12%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHA--PVYFETY-------DVHGDMPAVPPAVIESIP 386
           + ++PGDGIGP +     +V++A+     V FE          +  D  A+P A +E   
Sbjct: 7   LAVLPGDGIGPEIMAEAMKVLDAVEQKFQVRFERQFANVGGAAIDRDGKALPDATVEICQ 66

Query: 387 RNKVCLKGGLATP 425
            +   L G +  P
Sbjct: 67  ASDAILFGSVGGP 79



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>EFS_MOUSE (Q64355) Embryonal Fyn-associated substrate (SRC-interacting|
           protein) (Signal-integrating protein)
          Length = 560

 Score = 28.9 bits (63), Expect = 7.7
 Identities = 16/38 (42%), Positives = 19/38 (50%)
 Frame = -3

Query: 277 PVTRGPMPSPGMSVTGRGVPSPGRGM*VTVRRAPPPWP 164
           PV+  P PSP  S      P+PGR   +  R  PPP P
Sbjct: 310 PVSEAPAPSPAPS------PAPGRKGSIQDRPLPPPPP 341



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>BAG3_MOUSE (Q9JLV1) BAG family molecular chaperone regulator 3 (BCL-2-binding|
           athanogene-3) (BAG-3) (Bcl-2-binding protein Bis)
          Length = 577

 Score = 28.9 bits (63), Expect = 7.7
 Identities = 14/42 (33%), Positives = 19/42 (45%)
 Frame = -3

Query: 274 VTRGPMPSPGMSVTGRGVPSPGRGM*VTVRRAPPPWPGRDGA 149
           V+  P+P P  S     VPSP + +    + AP P P    A
Sbjct: 371 VSSAPIPCPSPSPAPSAVPSPPKNVAAEQKAAPSPAPAEPAA 412



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>MUC2_HUMAN (Q02817) Mucin-2 precursor (Intestinal mucin 2)|
          Length = 5179

 Score = 28.9 bits (63), Expect = 7.7
 Identities = 24/90 (26%), Positives = 33/90 (36%)
 Frame = -3

Query: 439  TPPPTGVARPPLRQTLLRGMDSMTAGGTAGMSPWTSYVSK*TGACMASMTCSTAPVTRGP 260
            TPPPT    PP+   +     + T   T   SP T+             T +T P T  P
Sbjct: 1493 TPPPTTTPSPPMTTPITPPASTTTLPPTTTPSPPTT-------------TTTTPPPTTTP 1539

Query: 259  MPSPGMSVTGRGVPSPGRGM*VTVRRAPPP 170
             P     +T    P+    +  T   +PPP
Sbjct: 1540 SPPTTTPIT---PPTSTTTLPPTTTPSPPP 1566



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>Y429_METAC (Q8TTK2) UPF0272 protein MA0429|
          Length = 396

 Score = 28.9 bits (63), Expect = 7.7
 Identities = 13/39 (33%), Positives = 20/39 (51%), Gaps = 5/39 (12%)
 Frame = +3

Query: 339 HGDMPAVPPAVIESIPRNKVCLKGG-----LATPVGGGV 440
           HG +P   PA +E + + K+  +GG     L TP G  +
Sbjct: 159 HGTLPVPAPATLEILRKGKLYFRGGSVNKELLTPTGAAI 197



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>LEU3_GEOSL (Q748X2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 362

 Score = 28.9 bits (63), Expect = 7.7
 Identities = 12/26 (46%), Positives = 18/26 (69%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHA 311
           V ++PGDGIGP V     +V++A+ A
Sbjct: 7   VAVLPGDGIGPEVMAEALRVLDAVEA 32



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>UCRI_PROMM (Q7V654) Cytochrome b6-f complex iron-sulfur subunit (EC 1.10.99.1)|
           (Rieske iron-sulfur protein)
           (Plastohydroquinone:plastocyanin oxidoreductase
           iron-sulfur protein) (ISP) (RISP)
          Length = 178

 Score = 28.9 bits (63), Expect = 7.7
 Identities = 14/30 (46%), Positives = 15/30 (50%)
 Frame = -3

Query: 343 PWTSYVSK*TGACMASMTCSTAPVTRGPMP 254
           PW S V+K    C  S   ST  V RGP P
Sbjct: 115 PWNSGVNKFVCPCHGSQYNSTGKVVRGPAP 144



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>SF3A2_HUMAN (Q15428) Splicing factor 3A subunit 2 (Spliceosome-associated|
           protein 62) (SAP 62) (SF3a66)
          Length = 464

 Score = 28.9 bits (63), Expect = 7.7
 Identities = 22/59 (37%), Positives = 25/59 (42%), Gaps = 4/59 (6%)
 Frame = +3

Query: 204 PRPGDGTPRPVTLIPGDGIGPLVTGAVEQVMEAMHAP---VYFETYDVHGDMPAV-PPA 368
           P PG   P PV   P  G+ P   G V      +H P   V+  T  VH   P V PPA
Sbjct: 283 PAPGVHPPAPVVHPPASGVHPPAPG-VHPPAPGVHPPAPGVHPPTSGVHPPAPGVHPPA 340



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>LEU3_CORDI (Q6NHM7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 339

 Score = 28.9 bits (63), Expect = 7.7
 Identities = 20/71 (28%), Positives = 34/71 (47%), Gaps = 7/71 (9%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDV-------HGDMPAVPPAVIESIPRN 392
           + +I GDGIGP VT    +V+ A+   +    YD+       +G++ A   A + S+  +
Sbjct: 3   LAVIGGDGIGPEVTAEALKVLNAVRDDIEVTDYDLGARRYLRNGELLA--DADLVSLREH 60

Query: 393 KVCLKGGLATP 425
              L G +  P
Sbjct: 61  DAILLGAIGAP 71



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>LEU3_SYNP6 (Q5MZ40) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 365

 Score = 28.9 bits (63), Expect = 7.7
 Identities = 10/24 (41%), Positives = 16/24 (66%)
 Frame = +3

Query: 234 VTLIPGDGIGPLVTGAVEQVMEAM 305
           +TL+PGDGIGP +      ++ A+
Sbjct: 7   ITLLPGDGIGPEIMAVTVDILRAI 30



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>LEU3_SILPO (Q5LWZ5) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 367

 Score = 26.2 bits (56), Expect(2) = 9.9
 Identities = 15/46 (32%), Positives = 21/46 (45%), Gaps = 11/46 (23%)
 Frame = +3

Query: 240 LIPGDGIGPLVTGAVEQVM-----------EAMHAPVYFETYDVHG 344
           ++PGDGIGP V   V +++           +     V    YDVHG
Sbjct: 8   ILPGDGIGPEVMAEVRKIIGWFGDKRGLNFDVSEDLVGGAAYDVHG 53



 Score = 20.8 bits (42), Expect(2) = 9.9
 Identities = 7/12 (58%), Positives = 12/12 (100%)
 Frame = +2

Query: 452 MQLRKELDLFAS 487
           ++LRKE+DLF++
Sbjct: 94  LRLRKEMDLFSN 105


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,643,659
Number of Sequences: 219361
Number of extensions: 856272
Number of successful extensions: 4533
Number of sequences better than 10.0: 139
Number of HSP's better than 10.0 without gapping: 4105
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4456
length of database: 80,573,946
effective HSP length: 103
effective length of database: 57,979,763
effective search space used: 3420806017
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
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