ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
menu 
| Clone Name | bart57d02 |
|---|---|
| Clone Library Name | barley_pub |
>ANR28_HUMAN (O15084) Ankyrin repeat domain-containing protein 28| Length = 1086 Score = 79.7 bits (195), Expect = 5e-15 Identities = 48/125 (38%), Positives = 69/125 (55%), Gaps = 2/125 (1%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLA--LNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXX 368 LH AA + E+L PL +N DR RT LH AA++GH ++VK L Sbjct: 144 LHIAAANKAVKCAEALV---PLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLLSRGANIN 200 Query: 369 XXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVR 548 IH+A+ GH+EVV+ L++ GA V K++K +T LH AA + + +VKYL+ Sbjct: 201 AFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLD 260 Query: 549 RGVDI 563 GVD+ Sbjct: 261 LGVDM 265 Score = 68.6 bits (166), Expect = 1e-11 Identities = 42/124 (33%), Positives = 65/124 (52%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH+A S AV+ L +N+RD+ +TPLH+AA V + L Sbjct: 111 LHRAVASCSEEAVQVLLKHSA-DVNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVS 169 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 +H A+ GH E+V+ LL+ GA++ A ++K A+H+AA H+E+VK LV G Sbjct: 170 DRAGRTALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHG 229 Query: 555 VDIT 566 ++T Sbjct: 230 AEVT 233 Score = 67.4 bits (163), Expect = 3e-11 Identities = 47/124 (37%), Positives = 61/124 (49%), Gaps = 1/124 (0%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 +H AA G V+ L S + +D+ S TPLH AA +G + VVK L Sbjct: 210 IHWAAYMGHIEVVKLLV-SHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEP 268 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLEL-VKYLVRR 551 +H A G VV EL+ GA V KN KGFT LHFAA ++H L ++ LV Sbjct: 269 NAYGNTPLHVACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGALCLELLVGN 328 Query: 552 GVDI 563 G D+ Sbjct: 329 GADV 332 Score = 60.8 bits (146), Expect = 3e-09 Identities = 41/123 (33%), Positives = 60/123 (48%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AA GDA +E L S +N++D TPLH A + + V+ L KH Sbjct: 78 LHAAAYLGDAEIIELLILSGA-RVNAKDSKWLTPLHRAVASCSEEAVQVLLKHSADVNAR 136 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 +H A+ ++ L+ ++V +R G TALH AA + H E+VK L+ RG Sbjct: 137 DKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLLSRG 196 Query: 555 VDI 563 +I Sbjct: 197 ANI 199 Score = 56.2 bits (134), Expect = 6e-08 Identities = 33/102 (32%), Positives = 51/102 (50%), Gaps = 4/102 (3%) Frame = +3 Query: 264 LNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVREL 443 ++++D+ RT LH A GH + V L +H IH ++ GH+ V+ L Sbjct: 712 VDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGAL 771 Query: 444 LASGASVKAK----NRKGFTALHFAAQNSHLELVKYLVRRGV 557 L S AS+ A + G+TALH+A N H V+ L+ + V Sbjct: 772 LQSAASMDANPATADNHGYTALHWACYNGHETCVELLLEQEV 813 Score = 53.9 bits (128), Expect = 3e-07 Identities = 34/122 (27%), Positives = 55/122 (45%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH A G + +++ S + ++ D+ TPLH+AA GH ++ L Sbjct: 343 LHMTALHGRFSRSQTIIQSGAV-IDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKR 401 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 +H A+ G + R+LL+SG + + G T LH AA +LE + L+ G Sbjct: 402 GIHGMFPLHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTG 461 Query: 555 VD 560 D Sbjct: 462 AD 463 Score = 50.8 bits (120), Expect = 3e-06 Identities = 38/123 (30%), Positives = 54/123 (43%), Gaps = 3/123 (2%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCL---CKHKXXX 365 L AA G V+ L + L L RTP+H AA GH + ++ L + + Sbjct: 620 LDLAAFKGHVECVDVLINQGASILVKDYILKRTPIHAAATNGHSECLRLLIGNAEPQNAV 679 Query: 366 XXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLV 545 + + GH + V LL GA+V AK++ G TALH A H E V L+ Sbjct: 680 DIQDGNGQTPLMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALL 739 Query: 546 RRG 554 + G Sbjct: 740 QHG 742 Score = 50.1 bits (118), Expect = 4e-06 Identities = 32/111 (28%), Positives = 50/111 (45%), Gaps = 2/111 (1%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLAL-NSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXX 371 LH A + + A E L D+ ++ N+ D RTPLH AA+ HV+ ++ L H Sbjct: 825 LHCAVINDNEGAAEMLIDTLGASIVNATDSKGRTPLHAAAFTDHVECLQLLLSHNAQVNS 884 Query: 372 XXXXXXXXIHFASQKGHLEVVRELLAS-GASVKAKNRKGFTALHFAAQNSH 521 + A++ G V L++S A + ++ TALH A H Sbjct: 885 VDSTGKTPLMMAAENGQTNTVEMLVSSASAELTLQDNSKNTALHLACSKGH 935 Score = 49.7 bits (117), Expect = 6e-06 Identities = 33/110 (30%), Positives = 53/110 (48%), Gaps = 1/110 (0%) Frame = +3 Query: 219 DAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXI 398 + + + L DSD +R + +PLHLAA+ GH ++ L + + Sbjct: 568 ETSGTDMLSDSD-------NRATISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPL 620 Query: 399 HFASQKGHLEVVRELLASGASVKAKNR-KGFTALHFAAQNSHLELVKYLV 545 A+ KGH+E V L+ GAS+ K+ T +H AA N H E ++ L+ Sbjct: 621 DLAAFKGHVECVDVLINQGASILVKDYILKRTPIHAAATNGHSECLRLLI 670 Score = 48.5 bits (114), Expect = 1e-05 Identities = 32/125 (25%), Positives = 52/125 (41%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AA S A L + +N + + +TPLH+ A G + + + Sbjct: 309 LHFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCE 368 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 +H A++ GH ++ L+ SGA + G LH AA + + + L+ G Sbjct: 369 DKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFSDCCRKLLSSG 428 Query: 555 VDITT 569 DI T Sbjct: 429 FDIDT 433 Score = 47.4 bits (111), Expect = 3e-05 Identities = 34/119 (28%), Positives = 58/119 (48%), Gaps = 1/119 (0%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AA SG + L S +++ D RT LH AA G+++ + L Sbjct: 409 LHLAALSGFSDCCRKLLSSG-FDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKK 467 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAA-QNSHLELVKYLVR 548 +H+A+ + + + L+ SGASV + +G T LH+AA ++ + ++YL+R Sbjct: 468 DKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAATSDTDGKCLEYLLR 526 Score = 46.6 bits (109), Expect = 5e-05 Identities = 34/110 (30%), Positives = 45/110 (40%), Gaps = 3/110 (2%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKH---KXXX 365 L AA +G VE L S L +D T LHLA GH + + + Sbjct: 893 LMMAAENGQTNTVEMLVSSASAELTLQDNSKNTALHLACSKGHETSALLILEKITDRNLI 952 Query: 366 XXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQN 515 +H A++ G VV+ELL GASV A + G+T A N Sbjct: 953 NATNAALQTPLHVAARNGLTMVVQELLGKGASVLAVDENGYTPALACAPN 1002 Score = 46.2 bits (108), Expect = 6e-05 Identities = 32/120 (26%), Positives = 56/120 (46%), Gaps = 2/120 (1%) Frame = +3 Query: 195 LHKAARSGDAAAVESLC-DSDPL-ALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXX 368 +H AA +G + + L +++P A++ +D +TPL L+ GH D V L Sbjct: 654 IHAAATNGHSECLRLLIGNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGANVD 713 Query: 369 XXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVR 548 +H + GH E V LL GA ++ +G T +H +A H+ ++ L++ Sbjct: 714 AKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGALLQ 773 Score = 38.1 bits (87), Expect = 0.018 Identities = 35/136 (25%), Positives = 52/136 (38%), Gaps = 13/136 (9%) Frame = +3 Query: 195 LHKAARSG-DAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGH------------VDVV 335 LH AA S D +E L +D RD+ +H +A GH +DV+ Sbjct: 508 LHYAATSDTDGKCLEYLLRNDANP-GVRDKQGYNAVHYSAAYGHRLCLQLIASETPLDVL 566 Query: 336 KCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQN 515 +H A+ GH + + L+ S + +N G T L AA Sbjct: 567 METSGTDMLSDSDNRATISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFK 626 Query: 516 SHLELVKYLVRRGVDI 563 H+E V L+ +G I Sbjct: 627 GHVECVDVLINQGASI 642
>RIPK4_HUMAN (P57078) Receptor-interacting serine/threonine-protein kinase 4 (EC| 2.7.11.1) (Ankyrin repeat domain protein 3) (PKC-delta-interacting protein kinase) Length = 832 Score = 77.4 bits (189), Expect = 3e-14 Identities = 46/125 (36%), Positives = 60/125 (48%) Frame = +3 Query: 189 LKLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXX 368 L LH AA G V+ L +++N++ RTPLHLAA GH V + L Sbjct: 620 LPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVN 679 Query: 369 XXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVR 548 +H A++ GH R LL GA +A G+TALH AA+N HL VK LV Sbjct: 680 VCSLLAQTPLHVAAETGHTSTARLLLHRGAGKEAMTSDGYTALHLAARNGHLATVKLLVE 739 Query: 549 RGVDI 563 D+ Sbjct: 740 EKADV 744 Score = 62.4 bits (150), Expect = 9e-10 Identities = 42/123 (34%), Positives = 57/123 (46%), Gaps = 2/123 (1%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCD--SDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXX 368 LH AA+ G L D SD +N L++TPLH+AA GH + L Sbjct: 656 LHLAAQRGHYRVARILIDLCSD---VNVCSLLAQTPLHVAAETGHTSTARLLLHRGAGKE 712 Query: 369 XXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVR 548 +H A++ GHL V+ L+ A V A+ TALH AA + H E+V+ LV Sbjct: 713 AMTSDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHGHSEVVEELVS 772 Query: 549 RGV 557 V Sbjct: 773 ADV 775 Score = 60.5 bits (145), Expect = 3e-09 Identities = 34/91 (37%), Positives = 48/91 (52%) Frame = +3 Query: 291 TPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKA 470 T LHLAA GH+ VK L + K +H A+ GH EVV EL+++ + Sbjct: 720 TALHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHGHSEVVEELVSADV-IDL 778 Query: 471 KNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 + +G +ALH AAQ H + V+ L+R G I Sbjct: 779 FDEQGLSALHLAAQGRHAQTVETLLRHGAHI 809 Score = 58.2 bits (139), Expect = 2e-08 Identities = 40/126 (31%), Positives = 59/126 (46%), Gaps = 2/126 (1%) Frame = +3 Query: 195 LHKAARSGDAAAVESLC--DSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXX 368 LH A +G + L +++P N +R TPLH+A VV+ L K Sbjct: 490 LHLAVEAGQEECAKWLLLNNANP---NLSNRRGSTPLHMAVERRVRGVVELLLARKISVN 546 Query: 369 XXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVR 548 +HFA+Q G R LL ASV + +G T +H A Q+ +V+ L+R Sbjct: 547 AKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQENIVRILLR 606 Query: 549 RGVDIT 566 RGVD++ Sbjct: 607 RGVDVS 612 Score = 52.0 bits (123), Expect = 1e-06 Identities = 36/124 (29%), Positives = 54/124 (43%), Gaps = 1/124 (0%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH A VE L + +++N++D T LH AA G + L + Sbjct: 523 LHMAVERRVRGVVELLL-ARKISVNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEV 581 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRR- 551 +H A Q G +VR LL G V + + + LH+AA HL +VK L ++ Sbjct: 582 DFEGRTPMHVACQHGQENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQP 641 Query: 552 GVDI 563 GV + Sbjct: 642 GVSV 645
>ANKR2_HUMAN (Q9GZV1) Ankyrin repeat domain-containing protein 2 (Skeletal| muscle ankyrin repeat protein) (hArpp) Length = 333 Score = 73.9 bits (180), Expect = 3e-13 Identities = 40/125 (32%), Positives = 66/125 (52%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH+A+ G +E L D+ ++ +DRL T +H A GH++VVK L H Sbjct: 158 LHRASLEGHMEILEKLLDNGA-TVDFQDRLDCTAMHWACRGGHLEVVKLLQSHGADTNVR 216 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 +H A + G +E+V L+ G + A++R+G TALH A + + +++K L+ G Sbjct: 217 DKLLSTPLHVAVRTGQVEIVEHFLSLGLEINARDREGDTALHDAVRLNRYKIIKLLLLHG 276 Query: 555 VDITT 569 D+ T Sbjct: 277 ADMMT 281 Score = 59.3 bits (142), Expect = 7e-09 Identities = 34/121 (28%), Positives = 63/121 (52%) Frame = +3 Query: 201 KAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXX 380 KAA G +E +D + ++ D+ RT LH A+ GH+++++ L + Sbjct: 127 KAAVEGKMKVIEKFL-ADGGSADTCDQFRRTALHRASLEGHMEILEKLLDNGATVDFQDR 185 Query: 381 XXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVD 560 +H+A + GHLEVV+ L + GA +++ T LH A + +E+V++ + G++ Sbjct: 186 LDCTAMHWACRGGHLEVVKLLQSHGADTNVRDKLLSTPLHVAVRTGQVEIVEHFLSLGLE 245 Query: 561 I 563 I Sbjct: 246 I 246
>GABP2_MOUSE (Q00420) GA-binding protein beta chain (GABP-beta-2 subunit)| (GABP-2) (GABP-beta-1 subunit) (GABPB-1) Length = 383 Score = 73.2 bits (178), Expect = 5e-13 Identities = 44/126 (34%), Positives = 65/126 (51%) Frame = +3 Query: 192 KLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXX 371 KL +AAR+G V L + A + D L +PLHLAA GH + L + Sbjct: 9 KLLEAARAGQDDEVRILMANG--APFTTDWLGTSPLHLAAQYGHFSTTEVLLRAGVSRDA 66 Query: 372 XXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRR 551 +H A+ +GH +V LL GA V AK+ TALH+A +++H E+V+ L++ Sbjct: 67 RTKVDRTPLHMAASEGHANIVEVLLKHGADVNAKDMLKMTALHWATEHNHQEVVELLIKY 126 Query: 552 GVDITT 569 G D+ T Sbjct: 127 GADVHT 132 Score = 62.4 bits (150), Expect = 9e-10 Identities = 36/116 (31%), Positives = 61/116 (52%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AA+ G + E L + ++ ++R ++ RTPLH+AA GH ++V+ L KH Sbjct: 42 LHLAAQYGHFSTTEVLLRAG-VSRDARTKVDRTPLHMAASEGHANIVEVLLKHGADVNAK 100 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYL 542 +H+A++ H EVV L+ GA V +++ TA + N + +L + L Sbjct: 101 DMLKMTALHWATEHNHQEVVELLIKYGADVHTQSKFCKTAFDISIDNGNEDLAEIL 156
>GABP2_HUMAN (Q06547) GA-binding protein beta chain (GABP-beta-2 subunit)| (GABP-2) (GABP-beta-1 subunit) (GABPB-1) (Transcription factor E4TF1-53) (Transcription factor E4TF1-47) (Nuclear respiratory factor 2) Length = 395 Score = 73.2 bits (178), Expect = 5e-13 Identities = 44/126 (34%), Positives = 65/126 (51%) Frame = +3 Query: 192 KLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXX 371 KL +AAR+G V L + A + D L +PLHLAA GH + L + Sbjct: 9 KLLEAARAGQDDEVRILMANG--APFTTDWLGTSPLHLAAQYGHYSTTEVLLRAGVSRDA 66 Query: 372 XXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRR 551 +H A+ +GH +V LL GA V AK+ TALH+A +++H E+V+ L++ Sbjct: 67 RTKVDRTPLHMAASEGHASIVEVLLKHGADVNAKDMLKMTALHWATEHNHQEVVELLIKY 126 Query: 552 GVDITT 569 G D+ T Sbjct: 127 GADVHT 132 Score = 62.0 bits (149), Expect = 1e-09 Identities = 36/116 (31%), Positives = 60/116 (51%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AA+ G + E L + ++ ++R ++ RTPLH+AA GH +V+ L KH Sbjct: 42 LHLAAQYGHYSTTEVLLRAG-VSRDARTKVDRTPLHMAASEGHASIVEVLLKHGADVNAK 100 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYL 542 +H+A++ H EVV L+ GA V +++ TA + N + +L + L Sbjct: 101 DMLKMTALHWATEHNHQEVVELLIKYGADVHTQSKFCKTAFDISIDNGNEDLAEIL 156
>ANK1_HUMAN (P16157) Ankyrin-1 (Erythrocyte ankyrin) (Ankyrin-R)| Length = 1880 Score = 72.8 bits (177), Expect = 6e-13 Identities = 45/121 (37%), Positives = 71/121 (58%), Gaps = 1/121 (0%) Frame = +3 Query: 201 KAARSGDA-AAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXX 377 +AARSG+ A++ L + + +N+ ++ LHLA+ GHV +V L + Sbjct: 17 RAARSGNLDKALDHLRNG--VDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETTT 74 Query: 378 XXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGV 557 +H A+ G EVVREL+ GA+V A+++KGFT L+ AAQ +HLE+VK+L+ G Sbjct: 75 KKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGA 134 Query: 558 D 560 + Sbjct: 135 N 135 Score = 71.6 bits (174), Expect = 1e-12 Identities = 43/120 (35%), Positives = 59/120 (49%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AA+ G A V L N ++ TPLHL A GHV V L KH Sbjct: 638 LHLAAQEGHAEMVALLLSKQANG-NLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDAT 696 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 +H AS G++++V+ LL A V AK + G++ LH AAQ H ++V L++ G Sbjct: 697 TRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNG 756 Score = 70.1 bits (170), Expect = 4e-12 Identities = 39/119 (32%), Positives = 62/119 (52%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AAR+G + L + +N++ + +TPLH AA GH ++VK L ++ Sbjct: 440 LHMAARAGHTEVAKYLLQNKA-KVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLA 498 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRR 551 +H A+++GH+E V LL AS +KGFT LH AA+ + + + L+ R Sbjct: 499 TTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLER 557 Score = 68.2 bits (165), Expect = 2e-11 Identities = 44/118 (37%), Positives = 55/118 (46%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AA G + L D NSR TPLH+A HV V++ L K Sbjct: 341 LHVAAHCGHHRVAKVLLDKGAKP-NSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAV 399 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVR 548 +H AS GHL +V+ LL GAS N K T LH AA+ H E+ KYL++ Sbjct: 400 TESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQ 457 Score = 67.4 bits (163), Expect = 3e-11 Identities = 39/123 (31%), Positives = 58/123 (47%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AA+ SL A N+ TPLHLAA GH ++V L + Sbjct: 605 LHIAAKQNQVEVARSLLQYGGSA-NAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLG 663 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 +H +Q+GH+ V L+ G V A R G+T LH A+ +++LVK+L++ Sbjct: 664 NKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQ 723 Query: 555 VDI 563 D+ Sbjct: 724 ADV 726 Score = 67.4 bits (163), Expect = 3e-11 Identities = 39/124 (31%), Positives = 63/124 (50%), Gaps = 1/124 (0%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSD-PLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXX 371 LH AAR+G E L D P+ +++ LS P+H+AA H+D V+ L ++ Sbjct: 275 LHCAARNGHVRISEILLDHGAPIQAKTKNGLS--PIHMAAQGDHLDCVRLLLQYDAEIDD 332 Query: 372 XXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRR 551 +H A+ GH V + LL GA ++ GFT LH A + +H+ +++ L++ Sbjct: 333 ITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKT 392 Query: 552 GVDI 563 G I Sbjct: 393 GASI 396 Score = 64.3 bits (155), Expect = 2e-10 Identities = 41/126 (32%), Positives = 64/126 (50%), Gaps = 3/126 (2%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRT---PLHLAAWAGHVDVVKCLCKHKXXX 365 LH AAR+ D L +DP + D LS+T PLH+AA +++V + L Sbjct: 176 LHIAARNDDTRTAAVLLQNDP----NPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASV 231 Query: 366 XXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLV 545 +H AS++G++ +VR LL GA ++ K + T LH AA+N H+ + + L+ Sbjct: 232 NFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILL 291 Query: 546 RRGVDI 563 G I Sbjct: 292 DHGAPI 297 Score = 62.8 bits (151), Expect = 7e-10 Identities = 38/120 (31%), Positives = 58/120 (48%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH A++ G V L + + L + + T LH+AA AG +VV+ L + Sbjct: 48 LHLASKEGHVKMVVELLHKE-IILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQ 106 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 ++ A+Q+ HLEVV+ LL +GA+ GFT L A Q H +V +L+ G Sbjct: 107 SQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLINYG 166 Score = 62.4 bits (150), Expect = 9e-10 Identities = 39/120 (32%), Positives = 58/120 (48%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AAR G V+ L +++ N TPLH+AA GHV+ V L + + Sbjct: 473 LHCAARIGHTNMVKLLLENNANP-NLATTAGHTPLHIAAREGHVETVLALLEKEASQACM 531 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 +H A++ G + V LL A A + G T LH A +++L++VK L+ RG Sbjct: 532 TKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRG 591 Score = 62.0 bits (149), Expect = 1e-09 Identities = 33/95 (34%), Positives = 49/95 (51%), Gaps = 2/95 (2%) Frame = +3 Query: 291 TPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKA 470 TPLH+AA V+V + L ++ +H A+Q+GH E+V LL+ A+ Sbjct: 603 TPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNL 662 Query: 471 KNRKGFTALHFAAQNSHLELVKYLVRRG--VDITT 569 N+ G T LH AQ H+ + L++ G VD TT Sbjct: 663 GNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATT 697 Score = 60.5 bits (145), Expect = 3e-09 Identities = 38/119 (31%), Positives = 58/119 (48%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH A+ G V++L S ++ TPLH+AA AGH +V K L ++K Sbjct: 407 LHVASFMGHLPIVKNLLQRGASPNVSNVKVE-TPLHMAARAGHTEVAKYLLQNKAKVNAK 465 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRR 551 +H A++ GH +V+ LL + A+ G T LH AA+ H+E V L+ + Sbjct: 466 AKDDQTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEK 524 Score = 60.5 bits (145), Expect = 3e-09 Identities = 36/122 (29%), Positives = 59/122 (48%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH A + +E L + ++++ TPLH+A++ GH+ +VK L + Sbjct: 374 LHIACKKNHVRVMELLLKTGA-SIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVS 432 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 +H A++ GH EV + LL + A V AK + T LH AA+ H +VK L+ Sbjct: 433 NVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENN 492 Query: 555 VD 560 + Sbjct: 493 AN 494 Score = 59.7 bits (143), Expect = 6e-09 Identities = 29/91 (31%), Positives = 49/91 (53%) Frame = +3 Query: 291 TPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKA 470 TPLH+A+ G+V +V+ L +H A++ GH+ + LL GA ++A Sbjct: 240 TPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQA 299 Query: 471 KNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 K + G + +H AAQ HL+ V+ L++ +I Sbjct: 300 KTKNGLSPIHMAAQGDHLDCVRLLLQYDAEI 330 Score = 57.8 bits (138), Expect = 2e-08 Identities = 41/121 (33%), Positives = 54/121 (44%), Gaps = 1/121 (0%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDP-LALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXX 371 LH A+R G+ V L D + ++D L TPLH AA GHV + + L H Sbjct: 242 LHIASRRGNVIMVRLLLDRGAQIETKTKDEL--TPLHCAARNGHVRISEILLDHGAPIQA 299 Query: 372 XXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRR 551 IH A+Q HL+ VR LL A + T LH AA H + K L+ + Sbjct: 300 KTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDK 359 Query: 552 G 554 G Sbjct: 360 G 360 Score = 54.3 bits (129), Expect = 2e-07 Identities = 32/116 (27%), Positives = 57/116 (49%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH A+ G + L + +++ R+ TPLH+A+ G++ +VK L +H+ Sbjct: 671 LHLVAQEGHVPVADVLIKHGVM-VDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAK 729 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYL 542 +H A+Q+GH ++V LL +GAS + G T L A + ++ + L Sbjct: 730 TKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTTPLAIAKRLGYISVTDVL 785 Score = 53.5 bits (127), Expect = 4e-07 Identities = 35/120 (29%), Positives = 57/120 (47%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AAR G V +L + + + + TPLH+AA G V V + L + Sbjct: 506 LHIAAREGHVETVLALLEKEA-SQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAA 564 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 +H A +L++V+ LL G S + G+T LH AA+ + +E+ + L++ G Sbjct: 565 GKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYG 624 Score = 47.8 bits (112), Expect = 2e-05 Identities = 38/152 (25%), Positives = 61/152 (40%), Gaps = 29/152 (19%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AA +G V L + +N++ + TPL++AA H++VVK L ++ Sbjct: 81 LHIAALAGQDEVVRELVNYGA-NVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVA 139 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAK--------------------------- 473 + A Q+GH VV L+ G K + Sbjct: 140 TEDGFTPLAVALQQGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPD 199 Query: 474 --NRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 ++ GFT LH AA +L + + L+ RG + Sbjct: 200 VLSKTGFTPLHIAAHYENLNVAQLLLNRGASV 231 Score = 45.4 bits (106), Expect = 1e-04 Identities = 29/103 (28%), Positives = 51/103 (49%) Frame = +3 Query: 255 PLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVV 434 P ++ R+ + T AA +G++D ++ +H AS++GH+++V Sbjct: 1 PYSVGFREADAATSFLRAARSGNLDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVKMV 60 Query: 435 RELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 ELL ++ +KG TALH AA E+V+ LV G ++ Sbjct: 61 VELLHKEIILETTTKKGNTALHIAALAGQDEVVRELVNYGANV 103 Score = 41.2 bits (95), Expect = 0.002 Identities = 26/91 (28%), Positives = 41/91 (45%) Frame = +3 Query: 297 LHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKN 476 LH+AA L ++ +H A+ +L V + LL GASV Sbjct: 176 LHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTP 235 Query: 477 RKGFTALHFAAQNSHLELVKYLVRRGVDITT 569 + G T LH A++ ++ +V+ L+ RG I T Sbjct: 236 QNGITPLHIASRRGNVIMVRLLLDRGAQIET 266
>ANK1_MOUSE (Q02357) Ankyrin-1 (Erythrocyte ankyrin)| Length = 1862 Score = 72.8 bits (177), Expect = 6e-13 Identities = 45/121 (37%), Positives = 71/121 (58%), Gaps = 1/121 (0%) Frame = +3 Query: 201 KAARSGDA-AAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXX 377 +AARSG+ A++ L + + +N+ ++ LHLA+ GHV +V L + Sbjct: 14 RAARSGNLDKALDHLRNG--VDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETTT 71 Query: 378 XXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGV 557 +H A+ G EVVREL+ GA+V A+++KGFT L+ AAQ +HLE+VK+L+ G Sbjct: 72 KKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGA 131 Query: 558 D 560 + Sbjct: 132 N 132 Score = 69.3 bits (168), Expect = 7e-12 Identities = 41/120 (34%), Positives = 58/120 (48%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AA+ G V L N ++ TPLHL + GHV V L KH Sbjct: 635 LHLAAQEGHTEMVALLLSKQANG-NLGNKSGLTPLHLVSQEGHVPVADVLIKHGVTVDAT 693 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 +H AS G++++V+ LL A V AK + G++ LH AAQ H ++V L++ G Sbjct: 694 TRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNG 753 Score = 68.9 bits (167), Expect = 9e-12 Identities = 40/123 (32%), Positives = 59/123 (47%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AA+ SL A N+ TPLHLAA GH ++V L + Sbjct: 602 LHIAAKQNQIEVARSLLQYGGSA-NAESVQGVTPLHLAAQEGHTEMVALLLSKQANGNLG 660 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 +H SQ+GH+ V L+ G +V A R G+T LH A+ +++LVK+L++ Sbjct: 661 NKSGLTPLHLVSQEGHVPVADVLIKHGVTVDATTRMGYTPLHVASHYGNIKLVKFLLQHQ 720 Query: 555 VDI 563 D+ Sbjct: 721 ADV 723 Score = 68.2 bits (165), Expect = 2e-11 Identities = 39/124 (31%), Positives = 63/124 (50%), Gaps = 1/124 (0%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSD-PLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXX 371 LH AAR+G E L D P+ +++ LS P+H+AA H+D V+ L ++ Sbjct: 272 LHCAARNGHVRISEILLDHGAPIQAKTKNGLS--PIHMAAQGDHLDCVRLLLQYNAEIDD 329 Query: 372 XXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRR 551 +H A+ GH V + LL GA ++ GFT LH A + +H+ +++ L++ Sbjct: 330 ITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHIRVMELLLKT 389 Query: 552 GVDI 563 G I Sbjct: 390 GASI 393 Score = 67.8 bits (164), Expect = 2e-11 Identities = 43/118 (36%), Positives = 55/118 (46%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AA G + L D NSR TPLH+A H+ V++ L K Sbjct: 338 LHVAAHCGHHRVAKVLLDKGAKP-NSRALNGFTPLHIACKKNHIRVMELLLKTGASIDAV 396 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVR 548 +H AS GHL +V+ LL GAS N K T LH AA+ H E+ KYL++ Sbjct: 397 TESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQ 454 Score = 65.5 bits (158), Expect = 1e-10 Identities = 38/117 (32%), Positives = 59/117 (50%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AAR+G + L + A N++ + +TPLH AA GH +VK L ++ Sbjct: 437 LHMAARAGHTEVAKYLLQNKAKA-NAKAKDDQTPLHCAARIGHTGMVKLLLENGASPNLA 495 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLV 545 +H A+++GH++ LL AS +KGFT LH AA+ + L + L+ Sbjct: 496 TTAGHTPLHTAAREGHVDTALALLEKEASQACMTKKGFTPLHVAAKYGKVRLAELLL 552 Score = 63.2 bits (152), Expect = 5e-10 Identities = 40/126 (31%), Positives = 64/126 (50%), Gaps = 3/126 (2%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRT---PLHLAAWAGHVDVVKCLCKHKXXX 365 LH AAR+ D L +DP + D LS+T PLH+AA +++V + L Sbjct: 173 LHIAARNDDTRTAAVLLQNDP----NPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASV 228 Query: 366 XXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLV 545 +H AS++G++ +VR LL GA ++ + + T LH AA+N H+ + + L+ Sbjct: 229 NFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETRTKDELTPLHCAARNGHVRISEILL 288 Query: 546 RRGVDI 563 G I Sbjct: 289 DHGAPI 294 Score = 62.8 bits (151), Expect = 7e-10 Identities = 38/120 (31%), Positives = 58/120 (48%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH A++ G V L + + L + + T LH+AA AG +VV+ L + Sbjct: 45 LHLASKEGHVKMVVELLHKE-IILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQ 103 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 ++ A+Q+ HLEVV+ LL +GA+ GFT L A Q H +V +L+ G Sbjct: 104 SQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLINYG 163 Score = 60.8 bits (146), Expect = 3e-09 Identities = 38/120 (31%), Positives = 56/120 (46%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AAR G V+ L ++ + N TPLH AA GHVD L + + Sbjct: 470 LHCAARIGHTGMVKLLLENGA-SPNLATTAGHTPLHTAAREGHVDTALALLEKEASQACM 528 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 +H A++ G + + LL A A + G T LH A +++L++VK L+ RG Sbjct: 529 TKKGFTPLHVAAKYGKVRLAELLLEHDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRG 588 Score = 60.5 bits (145), Expect = 3e-09 Identities = 28/91 (30%), Positives = 47/91 (51%) Frame = +3 Query: 291 TPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKA 470 TPLH+AA ++V + L ++ +H A+Q+GH E+V LL+ A+ Sbjct: 600 TPLHIAAKQNQIEVARSLLQYGGSANAESVQGVTPLHLAAQEGHTEMVALLLSKQANGNL 659 Query: 471 KNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 N+ G T LH +Q H+ + L++ GV + Sbjct: 660 GNKSGLTPLHLVSQEGHVPVADVLIKHGVTV 690 Score = 60.1 bits (144), Expect = 4e-09 Identities = 38/119 (31%), Positives = 58/119 (48%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH A+ G V++L S ++ TPLH+AA AGH +V K L ++K Sbjct: 404 LHVASFMGHLPIVKNLLQRGASPNVSNVKVE-TPLHMAARAGHTEVAKYLLQNKAKANAK 462 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRR 551 +H A++ GH +V+ LL +GAS G T LH AA+ H++ L+ + Sbjct: 463 AKDDQTPLHCAARIGHTGMVKLLLENGASPNLATTAGHTPLHTAAREGHVDTALALLEK 521 Score = 60.1 bits (144), Expect = 4e-09 Identities = 29/91 (31%), Positives = 49/91 (53%) Frame = +3 Query: 291 TPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKA 470 TPLH+A+ G+V +V+ L +H A++ GH+ + LL GA ++A Sbjct: 237 TPLHIASRRGNVIMVRLLLDRGAQIETRTKDELTPLHCAARNGHVRISEILLDHGAPIQA 296 Query: 471 KNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 K + G + +H AAQ HL+ V+ L++ +I Sbjct: 297 KTKNGLSPIHMAAQGDHLDCVRLLLQYNAEI 327 Score = 59.7 bits (143), Expect = 6e-09 Identities = 36/120 (30%), Positives = 58/120 (48%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH A + +E L + ++++ TPLH+A++ GH+ +VK L + Sbjct: 371 LHIACKKNHIRVMELLLKTGA-SIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVS 429 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 +H A++ GH EV + LL + A AK + T LH AA+ H +VK L+ G Sbjct: 430 NVKVETPLHMAARAGHTEVAKYLLQNKAKANAKAKDDQTPLHCAARIGHTGMVKLLLENG 489 Score = 58.9 bits (141), Expect = 1e-08 Identities = 40/120 (33%), Positives = 53/120 (44%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH A+R G+ V L D + +R + TPLH AA GHV + + L H Sbjct: 239 LHIASRRGNVIMVRLLLDRGA-QIETRTKDELTPLHCAARNGHVRISEILLDHGAPIQAK 297 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 IH A+Q HL+ VR LL A + T LH AA H + K L+ +G Sbjct: 298 TKNGLSPIHMAAQGDHLDCVRLLLQYNAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKG 357 Score = 54.7 bits (130), Expect = 2e-07 Identities = 34/120 (28%), Positives = 57/120 (47%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AAR G +L + + + + TPLH+AA G V + + L +H Sbjct: 503 LHTAAREGHVDTALALLEKEA-SQACMTKKGFTPLHVAAKYGKVRLAELLLEHDAHPNAA 561 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 +H A +L++V+ LL G S + G+T LH AA+ + +E+ + L++ G Sbjct: 562 GKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQIEVARSLLQYG 621 Score = 53.9 bits (128), Expect = 3e-07 Identities = 31/116 (26%), Positives = 57/116 (49%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH ++ G + L + +++ R+ TPLH+A+ G++ +VK L +H+ Sbjct: 668 LHLVSQEGHVPVADVLIKHG-VTVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAK 726 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYL 542 +H A+Q+GH ++V LL +GAS + G T L A + ++ + L Sbjct: 727 TKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSNGTTPLAIAKRLGYISVTDVL 782 Score = 47.8 bits (112), Expect = 2e-05 Identities = 38/152 (25%), Positives = 61/152 (40%), Gaps = 29/152 (19%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AA +G V L + +N++ + TPL++AA H++VVK L ++ Sbjct: 78 LHIAALAGQDEVVRELVNYGA-NVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVA 136 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAK--------------------------- 473 + A Q+GH VV L+ G K + Sbjct: 137 TEDGFTPLAVALQQGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPD 196 Query: 474 --NRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 ++ GFT LH AA +L + + L+ RG + Sbjct: 197 VLSKTGFTPLHIAAHYENLNVAQLLLNRGASV 228 Score = 43.9 bits (102), Expect = 3e-04 Identities = 22/56 (39%), Positives = 35/56 (62%) Frame = +3 Query: 396 IHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 +H AS++GH+++V ELL ++ +KG TALH AA E+V+ LV G ++ Sbjct: 45 LHLASKEGHVKMVVELLHKEIILETTTKKGNTALHIAALAGQDEVVRELVNYGANV 100 Score = 41.2 bits (95), Expect = 0.002 Identities = 26/91 (28%), Positives = 41/91 (45%) Frame = +3 Query: 297 LHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKN 476 LH+AA L ++ +H A+ +L V + LL GASV Sbjct: 173 LHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTP 232 Query: 477 RKGFTALHFAAQNSHLELVKYLVRRGVDITT 569 + G T LH A++ ++ +V+ L+ RG I T Sbjct: 233 QNGITPLHIASRRGNVIMVRLLLDRGAQIET 263
>ANK2_HUMAN (Q01484) Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin,| nonerythroid) Length = 3924 Score = 72.8 bits (177), Expect = 6e-13 Identities = 39/119 (32%), Positives = 66/119 (55%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AAR+G V L + L +++R R +TPLH+A+ G ++V+ L +H Sbjct: 468 LHMAARAGQVEVVRCLLRNGAL-VDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAA 526 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRR 551 +H ++++G ++V LL +GA+ +KGFT LH AA+ L++ K L++R Sbjct: 527 TTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQR 585 Score = 72.8 bits (177), Expect = 6e-13 Identities = 45/124 (36%), Positives = 65/124 (52%), Gaps = 1/124 (0%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSD-PLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXX 371 LH AARSG VE L + PL +++ LS PLH+AA HV+ VK L +HK Sbjct: 303 LHCAARSGHDQVVELLLERGAPLLARTKNGLS--PLHMAAQGDHVECVKHLLQHKAPVDD 360 Query: 372 XXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRR 551 +H A+ GH V + LL A+ A+ GFT LH A + + +++++ LV+ Sbjct: 361 VTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKY 420 Query: 552 GVDI 563 G I Sbjct: 421 GASI 424 Score = 72.8 bits (177), Expect = 6e-13 Identities = 41/123 (33%), Positives = 67/123 (54%) Frame = +3 Query: 201 KAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXX 380 +AAR+G+ V + +N+ ++ LHLAA GHV +V+ L Sbjct: 37 RAARAGNLDKVVEYLKGG-IDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATK 95 Query: 381 XXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVD 560 +H AS G EVV+ L+ GA++ A+++ GFT L+ AAQ +H+++VKYL+ G + Sbjct: 96 KGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGAN 155 Query: 561 ITT 569 +T Sbjct: 156 QST 158 Score = 68.2 bits (165), Expect = 2e-11 Identities = 41/130 (31%), Positives = 62/130 (47%), Gaps = 7/130 (5%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSD-------PLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKH 353 LH AAR D + L +D + +N TPLH+AA G+V+V L Sbjct: 196 LHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNR 255 Query: 354 KXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELV 533 +H AS++G+ +V+ LL G + AK R G T LH AA++ H ++V Sbjct: 256 GAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVV 315 Query: 534 KYLVRRGVDI 563 + L+ RG + Sbjct: 316 ELLLERGAPL 325 Score = 65.1 bits (157), Expect = 1e-10 Identities = 43/122 (35%), Positives = 61/122 (50%), Gaps = 2/122 (1%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCD--SDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXX 368 LH AA G + L D ++P N+R TPLH+A + V++ L K+ Sbjct: 369 LHVAAHCGHYRVTKLLLDKRANP---NARALNGFTPLHIACKKNRIKVMELLVKYGASIQ 425 Query: 369 XXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVR 548 IH A+ GHL +V LL +GAS N +G TALH AA+ +E+V+ L+R Sbjct: 426 AITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLR 485 Query: 549 RG 554 G Sbjct: 486 NG 487 Score = 63.5 bits (153), Expect = 4e-10 Identities = 40/118 (33%), Positives = 62/118 (52%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AA G+ V +L + A++ R TPLH+A+ G+ ++VK L Sbjct: 237 LHIAAHYGNVN-VATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAK 295 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVR 548 +H A++ GH +VV LL GA + A+ + G + LH AAQ H+E VK+L++ Sbjct: 296 TRDGLTPLHCAARSGHDQVVELLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQ 353 Score = 62.8 bits (151), Expect = 7e-10 Identities = 37/117 (31%), Positives = 57/117 (48%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AA+ G V+ L +++S + T LH+A+ AG +VVK L K Sbjct: 68 LHLAAKEGHVGLVQELLGRGS-SVDSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQ 126 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLV 545 ++ A+Q+ H++VV+ LL +GA+ GFT L A Q H + V L+ Sbjct: 127 SQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILL 183 Score = 60.5 bits (145), Expect = 3e-09 Identities = 38/120 (31%), Positives = 56/120 (46%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH A++ G V L D ++ + T LHLAA V+V L KH Sbjct: 666 LHLASQEGHTDMVTLLLDKGA-NIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAH 724 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 + A G++++V LL GA+V AK + G+T LH AAQ H ++ L++ G Sbjct: 725 TKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHG 784 Score = 58.5 bits (140), Expect = 1e-08 Identities = 28/90 (31%), Positives = 43/90 (47%) Frame = +3 Query: 291 TPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKA 470 TPLH+AA + + L + +H ASQ+GH ++V LL GA++ Sbjct: 631 TPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHM 690 Query: 471 KNRKGFTALHFAAQNSHLELVKYLVRRGVD 560 + G T+LH AAQ + + L + G D Sbjct: 691 STKSGLTSLHLAAQEDKVNVADILTKHGAD 720 Score = 58.2 bits (139), Expect = 2e-08 Identities = 30/86 (34%), Positives = 51/86 (59%) Frame = +3 Query: 291 TPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKA 470 TP+H+AA+ GH+++V L ++ +H A++ G +EVVR LL +GA V A Sbjct: 433 TPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDA 492 Query: 471 KNRKGFTALHFAAQNSHLELVKYLVR 548 + R+ T LH A++ E+V+ L++ Sbjct: 493 RAREEQTPLHIASRLGKTEIVQLLLQ 518 Score = 57.0 bits (136), Expect = 4e-08 Identities = 38/117 (32%), Positives = 55/117 (47%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH A++ G+ V+ L D ++++ R TPLH AA +GH VV+ L + Sbjct: 270 LHVASKRGNTNMVKLLLDRGG-QIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPLLAR 328 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLV 545 +H A+Q H+E V+ LL A V TALH AA H + K L+ Sbjct: 329 TKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLL 385 Score = 56.6 bits (135), Expect = 5e-08 Identities = 35/122 (28%), Positives = 57/122 (46%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH +AR G L ++ A + + TPLH+AA G +DV K L + + Sbjct: 534 LHISAREGQVDVASVLLEAGA-AHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSA 592 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 +H A+ + +V LL GAS A + G+T LH AA+ + +++ L+ G Sbjct: 593 GKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYG 652 Query: 555 VD 560 + Sbjct: 653 AE 654 Score = 55.5 bits (132), Expect = 1e-07 Identities = 29/88 (32%), Positives = 45/88 (51%) Frame = +3 Query: 291 TPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKA 470 T LH+AA AG V+VV+CL ++ +H AS+ G E+V+ LL A A Sbjct: 466 TALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDA 525 Query: 471 KNRKGFTALHFAAQNSHLELVKYLVRRG 554 G+T LH +A+ +++ L+ G Sbjct: 526 ATTNGYTPLHISAREGQVDVASVLLEAG 553 Score = 55.5 bits (132), Expect = 1e-07 Identities = 40/127 (31%), Positives = 59/127 (46%), Gaps = 3/127 (2%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSD-PLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXX 371 LH AA+ V+ L P+ + D L T LH+AA GH V K L + Sbjct: 336 LHMAAQGDHVECVKHLLQHKAPVDDVTLDYL--TALHVAAHCGHYRVTKLLLDKRANPNA 393 Query: 372 XXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRR 551 +H A +K ++V+ L+ GAS++A G T +H AA HL +V L++ Sbjct: 394 RALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQN 453 Query: 552 GV--DIT 566 G D+T Sbjct: 454 GASPDVT 460 Score = 54.3 bits (129), Expect = 2e-07 Identities = 34/123 (27%), Positives = 55/123 (44%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AA+ G + L A +S + TPLH+AA + V L + Sbjct: 567 LHVAAKYGSLDVAKLLLQRRAAA-DSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHAT 625 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 +H A++K +++ LL GA ++G T LH A+Q H ++V L+ +G Sbjct: 626 AKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKG 685 Query: 555 VDI 563 +I Sbjct: 686 ANI 688 Score = 50.1 bits (118), Expect = 4e-06 Identities = 35/122 (28%), Positives = 55/122 (45%), Gaps = 2/122 (1%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCD--SDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXX 368 LH A+R G V+ L + P A + TPLH++A G VDV L + Sbjct: 501 LHIASRLGKTEIVQLLLQHMAHPDAATTN---GYTPLHISAREGQVDVASVLLEAGAAHS 557 Query: 369 XXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVR 548 +H A++ G L+V + LL A+ + + G T LH AA + ++ L+ Sbjct: 558 LATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLE 617 Query: 549 RG 554 +G Sbjct: 618 KG 619 Score = 47.8 bits (112), Expect = 2e-05 Identities = 35/125 (28%), Positives = 54/125 (43%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AA+ D V + ++ +L TPL +A G+V +V L K Sbjct: 699 LHLAAQE-DKVNVADILTKHGADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAK 757 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 +H A+Q+GH ++ LL GA A G TAL A + ++ +V L Sbjct: 758 TKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYISVVDTLKVVT 817 Query: 555 VDITT 569 ++TT Sbjct: 818 EEVTT 822 Score = 45.8 bits (107), Expect = 8e-05 Identities = 33/118 (27%), Positives = 55/118 (46%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH A+ +G A V+ L + +N++ + TPL++AA H+DVVK L ++ Sbjct: 101 LHIASLAGQAEVVKVLV-KEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTA 159 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVR 548 + A Q+GH + V LL + K + ALH AA+ + L++ Sbjct: 160 TEDGFTPLAVALQQGHNQAVAILLENDTKGKVR----LPALHIAARKDDTKSAALLLQ 213
>ANK3_HUMAN (Q12955) Ankyrin-3 (ANK-3) (Ankyrin-G)| Length = 4377 Score = 72.4 bits (176), Expect = 8e-13 Identities = 43/120 (35%), Positives = 68/120 (56%), Gaps = 2/120 (1%) Frame = +3 Query: 201 KAARSGDAAAVESLCD--SDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 +AAR+G +E D + + +N ++ LHLA+ GHV+VV L + + Sbjct: 47 RAARAGH---LEKALDYIKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANVDAA 103 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 +H AS G EVV+ L+ +GA+V A+++ GFT L+ AAQ +HLE+VK+L+ G Sbjct: 104 TKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNG 163 Score = 71.2 bits (173), Expect = 2e-12 Identities = 40/119 (33%), Positives = 63/119 (52%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AARSG A V L D + ++ + +TPLH++A G D+V+ L + Sbjct: 470 LHMAARSGQAEVVRYLVQ-DGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAA 528 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRR 551 +H ++++GH +V LL GAS+ +KGFT LH AA+ LE+ L+++ Sbjct: 529 TTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQK 587 Score = 69.7 bits (169), Expect = 5e-12 Identities = 41/123 (33%), Positives = 60/123 (48%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AA G + L D N++ TPLH+A + V++ L KH Sbjct: 371 LHVAAHCGHYKVAKVLLDKKANP-NAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAV 429 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 IH A+ GH+ +V +L+ GAS N +G TALH AA++ E+V+YLV+ G Sbjct: 430 TESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDG 489 Query: 555 VDI 563 + Sbjct: 490 AQV 492 Score = 68.2 bits (165), Expect = 2e-11 Identities = 40/124 (32%), Positives = 64/124 (51%), Gaps = 1/124 (0%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCD-SDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXX 371 LH ARSG VE L D + P+ +++ LS PLH+A H++ V+ L +H Sbjct: 305 LHCGARSGHEQVVEMLLDRAAPILSKTKNGLS--PLHMATQGDHLNCVQLLLQHNVPVDD 362 Query: 372 XXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRR 551 +H A+ GH +V + LL A+ AK GFT LH A + + +++++ L++ Sbjct: 363 VTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKH 422 Query: 552 GVDI 563 G I Sbjct: 423 GASI 426 Score = 68.2 bits (165), Expect = 2e-11 Identities = 41/123 (33%), Positives = 61/123 (49%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AAR D A L +D A + + TPLH+AA G+++V L Sbjct: 206 LHIAARKDDTKAAALLLQNDNNA-DVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFT 264 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 +H AS++G+ +V+ LL GA + AK R G T LH A++ H ++V+ L+ R Sbjct: 265 ARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRA 324 Query: 555 VDI 563 I Sbjct: 325 API 327 Score = 63.2 bits (152), Expect = 5e-10 Identities = 29/91 (31%), Positives = 47/91 (51%) Frame = +3 Query: 291 TPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKA 470 TPLH+AA +D+ L ++ +H A+Q+GH+++V LL A+V Sbjct: 633 TPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANVNL 692 Query: 471 KNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 N+ G T LH AAQ + + + LV +G + Sbjct: 693 SNKSGLTPLHLAAQEDRVNVAEVLVNQGAHV 723 Score = 63.2 bits (152), Expect = 5e-10 Identities = 31/88 (35%), Positives = 50/88 (56%) Frame = +3 Query: 291 TPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKA 470 TP+H+AA+ GHV++V L H +H A++ G EVVR L+ GA V+A Sbjct: 435 TPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEA 494 Query: 471 KNRKGFTALHFAAQNSHLELVKYLVRRG 554 K + T LH +A+ ++V+ L+++G Sbjct: 495 KAKDDQTPLHISARLGKADIVQQLLQQG 522 Score = 60.8 bits (146), Expect = 3e-09 Identities = 37/117 (31%), Positives = 57/117 (48%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH A++ G V L + +++ + T LH+A+ AG +VVK L + Sbjct: 78 LHLASKEGHVEVVSELLQREA-NVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQ 136 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLV 545 ++ A+Q+ HLEVV+ LL +GAS GFT L A Q H ++V L+ Sbjct: 137 SQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLL 193 Score = 60.1 bits (144), Expect = 4e-09 Identities = 40/120 (33%), Positives = 54/120 (45%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH +AR G A V+ L + N+ TPLHL+A GH DV L H Sbjct: 503 LHISARLGKADIVQQLLQQGA-SPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSIT 561 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 +H A++ G LEV LL AS A + G T LH AA + ++ L+ +G Sbjct: 562 TKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQG 621 Score = 58.9 bits (141), Expect = 1e-08 Identities = 37/102 (36%), Positives = 53/102 (51%), Gaps = 4/102 (3%) Frame = +3 Query: 270 SRDRLSRTPLHL----AAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVR 437 SRDR ++ + AA AGH++ K+ +H AS++GH+EVV Sbjct: 32 SRDRKKKSDANASYLRAARAGHLEKALDYIKNGVDINICNQNGLNALHLASKEGHVEVVS 91 Query: 438 ELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 ELL A+V A +KG TALH A+ E+VK LV G ++ Sbjct: 92 ELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANV 133 Score = 58.5 bits (140), Expect = 1e-08 Identities = 37/123 (30%), Positives = 59/123 (47%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AA G+ V +L + A++ R TPLH+A+ G+ ++VK L Sbjct: 239 LHIAAHYGNIN-VATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAK 297 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 +H ++ GH +VV LL A + +K + G + LH A Q HL V+ L++ Sbjct: 298 TRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHN 357 Query: 555 VDI 563 V + Sbjct: 358 VPV 360 Score = 58.2 bits (139), Expect = 2e-08 Identities = 35/118 (29%), Positives = 54/118 (45%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 +H AA+ G V L + +N ++ TPLHLAA V+V + L Sbjct: 668 VHLAAQEGHVDMVSLLLGRNA-NVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQ 726 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVR 548 +H G++++V LL A V AK + G+T LH AAQ H ++ L++ Sbjct: 727 TKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQ 784 Score = 57.8 bits (138), Expect = 2e-08 Identities = 35/126 (27%), Positives = 59/126 (46%), Gaps = 2/126 (1%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCD--SDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXX 368 +H AA G V L + P N R T LH+AA +G +VV+ L + Sbjct: 437 IHVAAFMGHVNIVSQLMHHGASPNTTNVR---GETALHMAARSGQAEVVRYLVQDGAQVE 493 Query: 369 XXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVR 548 +H +++ G ++V++LL GAS A G+T LH +A+ H ++ +L+ Sbjct: 494 AKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLD 553 Query: 549 RGVDIT 566 G ++ Sbjct: 554 HGASLS 559 Score = 57.8 bits (138), Expect = 2e-08 Identities = 39/126 (30%), Positives = 56/126 (44%), Gaps = 1/126 (0%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSD-PLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXX 371 LH A + V+ L + P+ + D L T LH+AA GH V K L K Sbjct: 338 LHMATQGDHLNCVQLLLQHNVPVDDVTNDYL--TALHVAAHCGHYKVAKVLLDKKANPNA 395 Query: 372 XXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRR 551 +H A +K ++V+ LL GAS++A G T +H AA H+ +V L+ Sbjct: 396 KALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHH 455 Query: 552 GVDITT 569 G T Sbjct: 456 GASPNT 461 Score = 55.5 bits (132), Expect = 1e-07 Identities = 37/117 (31%), Positives = 53/117 (45%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH A++ G+A V+ L D ++++ R TPLH A +GH VV+ L Sbjct: 272 LHVASKRGNANMVKLLLDRGA-KIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSK 330 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLV 545 +H A+Q HL V+ LL V TALH AA H ++ K L+ Sbjct: 331 TKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLL 387 Score = 54.7 bits (130), Expect = 2e-07 Identities = 33/123 (26%), Positives = 55/123 (44%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AA+ +L + A N+ R +HLAA GHVD+V L Sbjct: 635 LHIAAKKNQMDIATTLLEYGADA-NAVTRQGIASVHLAAQEGHVDMVSLLLGRNANVNLS 693 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 +H A+Q+ + V L+ GA V A+ + G+T LH ++++V +L++ Sbjct: 694 NKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHS 753 Query: 555 VDI 563 + Sbjct: 754 AKV 756 Score = 54.3 bits (129), Expect = 2e-07 Identities = 32/123 (26%), Positives = 54/123 (43%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AA+ G L + ++ + TPLH+AA + V L Sbjct: 569 LHVAAKYGKLEVANLLLQKSA-SPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAA 627 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 +H A++K +++ LL GA A R+G ++H AAQ H+++V L+ R Sbjct: 628 AKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRN 687 Query: 555 VDI 563 ++ Sbjct: 688 ANV 690 Score = 53.9 bits (128), Expect = 3e-07 Identities = 35/122 (28%), Positives = 55/122 (45%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH +AR G L D +L+ + TPLH+AA G ++V L + Sbjct: 536 LHLSAREGHEDVAAFLLDHGA-SLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAA 594 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 +H A+ + +V LL GAS A + G+T LH AA+ + +++ L+ G Sbjct: 595 GKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYG 654 Query: 555 VD 560 D Sbjct: 655 AD 656 Score = 49.3 bits (116), Expect = 8e-06 Identities = 30/116 (25%), Positives = 54/116 (46%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AA+ D V + + ++++ ++ TPLH+ G++ +V L +H Sbjct: 701 LHLAAQE-DRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAK 759 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYL 542 +H A+Q+GH ++ LL + AS G TAL A + ++ +V L Sbjct: 760 TKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTALGIARRLGYISVVDTL 815 Score = 43.9 bits (102), Expect = 3e-04 Identities = 33/118 (27%), Positives = 56/118 (47%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH A+ +G A V+ L ++ +N++ + TPL++AA H++VVK L + Sbjct: 111 LHIASLAGQAEVVKVLV-TNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLA 169 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVR 548 + A Q+GH +VV LL + K + ALH AA+ + L++ Sbjct: 170 TEDGFTPLAVALQQGHDQVVSLLLENDTKGKVR----LPALHIAARKDDTKAAALLLQ 223 Score = 40.4 bits (93), Expect = 0.004 Identities = 29/120 (24%), Positives = 49/120 (40%) Frame = +3 Query: 204 AARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXX 383 A + G V L ++D ++ ++ LH+AA L ++ Sbjct: 180 ALQQGHDQVVSLLLEND-----TKGKVRLPALHIAARKDDTKAAALLLQNDNNADVESKS 234 Query: 384 XXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 +H A+ G++ V LL A+V R T LH A++ + +VK L+ RG I Sbjct: 235 GFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKI 294
>TNKS1_HUMAN (O95271) Tankyrase 1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1)| (TRF1-interacting ankyrin-related ADP-ribose polymerase) Length = 1327 Score = 70.1 bits (170), Expect = 4e-12 Identities = 43/127 (33%), Positives = 58/127 (45%) Frame = +3 Query: 186 DLKLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXX 365 D +L +A+++GD V+ LC S + + TPLH AA V VV+ L H Sbjct: 651 DYRLLEASKAGDLETVKQLCSSQNVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADV 710 Query: 366 XXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLV 545 +H A GH EV L+ GASV + FT LH AA E+ K L+ Sbjct: 711 HAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLL 770 Query: 546 RRGVDIT 566 + G D T Sbjct: 771 KHGADPT 777 Score = 65.1 bits (157), Expect = 1e-10 Identities = 43/129 (33%), Positives = 61/129 (47%), Gaps = 2/129 (1%) Frame = +3 Query: 186 DLKLHKAARSGDAAAVESLCDSDPLALNSRDRLSR--TPLHLAAWAGHVDVVKCLCKHKX 359 D L AA+ G A V+ LC P +N RD R TPLHLAA +++V + L +H Sbjct: 804 DAALLDAAKKGCLARVQKLCT--PENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGA 861 Query: 360 XXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKY 539 +H A+ GH+++ L+ V A ++ FT LH AAQ +L Sbjct: 862 DVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCAL 921 Query: 540 LVRRGVDIT 566 L+ G D T Sbjct: 922 LLAHGADPT 930 Score = 63.2 bits (152), Expect = 5e-10 Identities = 42/125 (33%), Positives = 59/125 (47%) Frame = +3 Query: 192 KLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXX 371 +L +AARSG+ + +L + ++ D TPLHLAA V +V+ L +H Sbjct: 338 ELLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHA 397 Query: 372 XXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRR 551 +H A GH EV LL GA V A + FT LH AA + +E+ L+ Sbjct: 398 KDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSH 457 Query: 552 GVDIT 566 G D T Sbjct: 458 GADPT 462 Score = 60.1 bits (144), Expect = 4e-09 Identities = 41/125 (32%), Positives = 62/125 (49%), Gaps = 2/125 (1%) Frame = +3 Query: 192 KLHKAARSGDAAAVESLCDSDPLALNSRDRLSR--TPLHLAAWAGHVDVVKCLCKHKXXX 365 +L +A R+GD + V+ L D+ +N++D R +PLH AA G DVV+ L + Sbjct: 185 ELLEACRNGDVSRVKRLVDA--ANVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQMGANV 242 Query: 366 XXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLV 545 +H A GH EVV LL GA A++ +T LH AA +++ L+ Sbjct: 243 HARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLL 302 Query: 546 RRGVD 560 + G D Sbjct: 303 QHGAD 307 Score = 53.1 bits (126), Expect = 5e-07 Identities = 35/104 (33%), Positives = 49/104 (47%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AA + E L + +N++D+ PLH AA GHVD+ L K+ Sbjct: 841 LHLAAGYNNLEVAEYLLEHGA-DVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVNAT 899 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFA 506 +H A+QKG ++ LLA GA KN++G T L A Sbjct: 900 DKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLA 943 Score = 48.1 bits (113), Expect = 2e-05 Identities = 26/77 (33%), Positives = 40/77 (51%) Frame = +3 Query: 264 LNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVREL 443 +N +++ TPLH+AA H DV++ L KH +H A+ GHL+ R L Sbjct: 551 VNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRAALAGHLQTCRLL 610 Query: 444 LASGASVKAKNRKGFTA 494 L+ G+ + +GFTA Sbjct: 611 LSYGSDPSIISLQGFTA 627 Score = 46.6 bits (109), Expect = 5e-05 Identities = 32/101 (31%), Positives = 45/101 (44%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AA + VE L ++++D+ PLH A GH +V + L +H Sbjct: 688 LHFAAGYNRVSVVEYLLHHGA-DVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVA 746 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTAL 497 +H A+ KG E+ + LL GA KNR G T L Sbjct: 747 DLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPL 787 Score = 40.8 bits (94), Expect = 0.003 Identities = 34/125 (27%), Positives = 54/125 (43%), Gaps = 3/125 (2%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHV---DVVKCLCKHKXXX 365 L +AAR D A V+ + + + + T LH A + H V + L + Sbjct: 493 LLQAAREADLAKVKKTLALEIINFK-QPQSHETALHCAVASLHPKRKQVTELLLRKGANV 551 Query: 366 XXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLV 545 +H A+++ H +V+ L GA + A + G TALH AA HL+ + L+ Sbjct: 552 NEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRAALAGHLQTCRLLL 611 Query: 546 RRGVD 560 G D Sbjct: 612 SYGSD 616 Score = 39.7 bits (91), Expect = 0.006 Identities = 26/92 (28%), Positives = 40/92 (43%) Frame = +3 Query: 264 LNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVREL 443 ++++D+ PLH A GH +V + L KH +H A+ K +EV L Sbjct: 395 VHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLL 454 Query: 444 LASGASVKAKNRKGFTALHFAAQNSHLELVKY 539 L+ GA N G +A+ A E + Y Sbjct: 455 LSHGADPTLVNCHGKSAVDMAPTPELRERLTY 486
>ANKR2_MOUSE (Q9WV06) Ankyrin repeat domain-containing protein 2 (Skeletal| muscle ankyrin repeat protein) (mArpp) Length = 328 Score = 69.3 bits (168), Expect = 7e-12 Identities = 37/123 (30%), Positives = 65/123 (52%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH+A+ G +E L ++ ++ +DRL T +H A GH++VV+ L Sbjct: 154 LHRASLEGHMEILEKLLENGA-TVDFQDRLDCTAMHWACRGGHLEVVRLLQSRGADTNVR 212 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 +H A + GH+E+V L+ G + AK+R+G +ALH A + + +++K L+ G Sbjct: 213 DKLLSTPLHVAVRTGHVEIVEHFLSLGLDINAKDREGDSALHDAVRLNRYKIIKLLLLHG 272 Query: 555 VDI 563 D+ Sbjct: 273 ADM 275 Score = 63.9 bits (154), Expect = 3e-10 Identities = 36/121 (29%), Positives = 64/121 (52%) Frame = +3 Query: 201 KAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXX 380 KAA G ++ +D + ++ D RT LH A+ GH+++++ L ++ Sbjct: 123 KAAVEGKMKVIDKYL-ADGGSADTCDEFRRTALHRASLEGHMEILEKLLENGATVDFQDR 181 Query: 381 XXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVD 560 +H+A + GHLEVVR L + GA +++ T LH A + H+E+V++ + G+D Sbjct: 182 LDCTAMHWACRGGHLEVVRLLQSRGADTNVRDKLLSTPLHVAVRTGHVEIVEHFLSLGLD 241 Query: 561 I 563 I Sbjct: 242 I 242
>EHMT1_HUMAN (Q9H9B1) Histone-lysine N-methyltransferase, H3 lysine-9 specific 5| (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a-like protein 1) (GLP1) Length = 1267 Score = 66.6 bits (161), Expect = 5e-11 Identities = 41/122 (33%), Positives = 61/122 (50%), Gaps = 1/122 (0%) Frame = +3 Query: 192 KLHKAARSGDAAAVE-SLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXX 368 +L+ +AR G+ V L D + R+PLH AA AGHVD+ L + Sbjct: 710 QLYFSARQGELQKVLLMLVDGIDPNFKMEHQNKRSPLHAAAEAGHVDICHMLVQAGANID 769 Query: 369 XXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVR 548 + A++ HLE V+ L+ +GA V K+ +G T LH AA+ H E+V+YL+ Sbjct: 770 TCSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLS 829 Query: 549 RG 554 G Sbjct: 830 NG 831 Score = 53.9 bits (128), Expect = 3e-07 Identities = 35/124 (28%), Positives = 57/124 (45%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AA+ G V+ L + + +N +D TP+ A HVD+VK L Sbjct: 812 LHLAAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIR 871 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 +H+A+ G +++ LLA+ + A N G + LH AA+ + + V + R Sbjct: 872 DNEENICLHWAAFSGCVDIAEILLAAKCDLHAVNIHGDSPLHIAARENRYDCVVLFLSRD 931 Query: 555 VDIT 566 D+T Sbjct: 932 SDVT 935 Score = 41.6 bits (96), Expect = 0.002 Identities = 25/87 (28%), Positives = 41/87 (47%) Frame = +3 Query: 264 LNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVREL 443 +N RD LH AA++G VD+ + L K +H A+++ + V Sbjct: 868 INIRDNEENICLHWAAFSGCVDIAEILLAAKCDLHAVNIHGDSPLHIAARENRYDCVVLF 927 Query: 444 LASGASVKAKNRKGFTALHFAAQNSHL 524 L+ + V KN++G T L A+ NS + Sbjct: 928 LSRDSDVTLKNKEGETPLQCASLNSQV 954
>GABP3_MOUSE (P81069) GA-binding protein beta-2-1 chain (GABP-beta-2-1 subunit)| (GABPB2-1) Length = 414 Score = 66.6 bits (161), Expect = 5e-11 Identities = 41/124 (33%), Positives = 62/124 (50%) Frame = +3 Query: 192 KLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXX 371 +L +AAR G V L + A + D L +PLHLAA GH + L + Sbjct: 9 RLLEAARKGQDDEVRILMANG--APFTTDWLGTSPLHLAAQYGHYSTAEVLLRAGVSRDA 66 Query: 372 XXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRR 551 +H A+ GH+ +V L+ SGA V AK+ TALH+A ++ H +V+ L++ Sbjct: 67 RTKVDRTPLHMAAADGHVHIVELLVRSGADVNAKDMLQMTALHWATEHHHRLVVELLIKY 126 Query: 552 GVDI 563 G D+ Sbjct: 127 GADV 130 Score = 53.5 bits (127), Expect = 4e-07 Identities = 34/116 (29%), Positives = 60/116 (51%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AA+ G + E L + ++ ++R ++ RTPLH+AA GHV +V+ L + Sbjct: 42 LHLAAQYGHYSTAEVLLRAG-VSRDARTKVDRTPLHMAAADGHVHIVELLVRSGADVNAK 100 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYL 542 +H+A++ H VV L+ GA V A ++ +A A + ++ E++ L Sbjct: 101 DMLQMTALHWATEHHHRLVVELLIKYGADVYAFSKFDKSAFDIAMEKNNTEILVML 156
>TNKS2_HUMAN (Q9H2K2) Tankyrase 2 (EC 2.4.2.30) (TANK2) (Tankyrase II) (TNKS-2)| (TRF1-interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase-like protein) (Tankyrase-related protein) Length = 1166 Score = 66.6 bits (161), Expect = 5e-11 Identities = 42/127 (33%), Positives = 57/127 (44%) Frame = +3 Query: 186 DLKLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXX 365 D +L +AA++GD V+ LC + + TPLH AA V VV+ L +H Sbjct: 493 DRQLLEAAKAGDVETVKKLCTVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADV 552 Query: 366 XXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLV 545 +H A GH EV L+ GA V + FT LH AA E+ K L+ Sbjct: 553 HAKDKGGLVPLHNACSYGHYEVAELLVKHGAVVNVADLWKFTPLHEAAAKGKYEICKLLL 612 Query: 546 RRGVDIT 566 + G D T Sbjct: 613 QHGADPT 619 Score = 64.3 bits (155), Expect = 2e-10 Identities = 45/129 (34%), Positives = 62/129 (48%), Gaps = 2/129 (1%) Frame = +3 Query: 186 DLKLHKAARSGDAAAVESLCDSDPLALNSRDRLSR--TPLHLAAWAGHVDVVKCLCKHKX 359 D L AA+ G A V+ L S P +N RD R TPLHLAA +++V + L +H Sbjct: 646 DAALLDAAKKGCLARVKKL--SSPDNVNCRDTQGRHSTPLHLAAGYNNLEVAEYLLQHGA 703 Query: 360 XXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKY 539 +H A+ GH++V L+ A V A ++ FT LH AAQ +L Sbjct: 704 DVNAQDKGGLIPLHNAASYGHVDVAALLIKYNACVNATDKWAFTPLHEAAQKGRTQLCAL 763 Query: 540 LVRRGVDIT 566 L+ G D T Sbjct: 764 LLAHGADPT 772 Score = 63.5 bits (153), Expect = 4e-10 Identities = 44/127 (34%), Positives = 62/127 (48%), Gaps = 2/127 (1%) Frame = +3 Query: 192 KLHKAARSGDAAAVESLCDSDPLALNSRDRLSR--TPLHLAAWAGHVDVVKCLCKHKXXX 365 +L +A R+GD V+ L P +NSRD R TPLH AA G DVV+ L ++ Sbjct: 27 ELFEACRNGDVERVKRLVT--PEKVNSRDTAGRKSTPLHFAAGFGRKDVVEYLLQNGANV 84 Query: 366 XXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLV 545 +H A GH EVV LL GA A++ +T LH AA +++ L+ Sbjct: 85 QARDDGGLIPLHNACSFGHAEVVNLLLRHGADPNARDNWNYTPLHEAAIKGKIDVCIVLL 144 Query: 546 RRGVDIT 566 + G + T Sbjct: 145 QHGAEPT 151 Score = 60.5 bits (145), Expect = 3e-09 Identities = 40/125 (32%), Positives = 59/125 (47%) Frame = +3 Query: 192 KLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXX 371 +L ++ARSG+ + +L + ++ D TPLHLAA V +V+ L +H Sbjct: 180 ELLESARSGNEEKMMALLTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHA 239 Query: 372 XXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRR 551 +H A GH EV L+ GA V A + FT LH AA + +E+ L+ Sbjct: 240 KDKGDLVPLHNACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSY 299 Query: 552 GVDIT 566 G D T Sbjct: 300 GADPT 304 Score = 53.1 bits (126), Expect = 5e-07 Identities = 30/100 (30%), Positives = 50/100 (50%) Frame = +3 Query: 264 LNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVREL 443 +N + + TPLH+A+ H DVV+ + KH+ +H A+ GHL+ R L Sbjct: 393 INEKTKEFLTPLHVASEKAHNDVVEVVVKHEAKVNALDNLGQTSLHRAAYCGHLQTCRLL 452 Query: 444 LASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 L+ G + +GFTAL +N V+ L++ G+ + Sbjct: 453 LSYGCDPNIISLQGFTALQMGNEN-----VQQLLQEGISL 487 Score = 51.6 bits (122), Expect = 2e-06 Identities = 35/101 (34%), Positives = 47/101 (46%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AA + E L +N++D+ PLH AA GHVDV L K+ Sbjct: 683 LHLAAGYNNLEVAEYLLQHGA-DVNAQDKGGLIPLHNAASYGHVDVAALLIKYNACVNAT 741 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTAL 497 +H A+QKG ++ LLA GA KN++G T L Sbjct: 742 DKWAFTPLHEAAQKGRTQLCALLLAHGADPTLKNQEGQTPL 782 Score = 47.8 bits (112), Expect = 2e-05 Identities = 33/101 (32%), Positives = 45/101 (44%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AA + VE L ++++D+ PLH A GH +V + L KH Sbjct: 530 LHFAAGYNRVSVVEYLLQHGA-DVHAKDKGGLVPLHNACSYGHYEVAELLVKHGAVVNVA 588 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTAL 497 +H A+ KG E+ + LL GA KNR G T L Sbjct: 589 DLWKFTPLHEAAAKGKYEICKLLLQHGADPTKKNRDGNTPL 629 Score = 45.8 bits (107), Expect = 8e-05 Identities = 35/104 (33%), Positives = 45/104 (43%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AA G VE L + + +RD PLH A GH +VV L +H Sbjct: 62 LHFAAGFGRKDVVEYLLQNGA-NVQARDDGGLIPLHNACSFGHAEVVNLLLRHGADPNAR 120 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFA 506 +H A+ KG ++V LL GA +N G TAL A Sbjct: 121 DNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLA 164 Score = 37.4 bits (85), Expect = 0.030 Identities = 25/92 (27%), Positives = 39/92 (42%) Frame = +3 Query: 264 LNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVREL 443 ++++D+ PLH A GH +V + L KH +H A+ K +EV L Sbjct: 237 VHAKDKGDLVPLHNACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLL 296 Query: 444 LASGASVKAKNRKGFTALHFAAQNSHLELVKY 539 L+ GA N +A+ A E + Y Sbjct: 297 LSYGADPTLLNCHNKSAIDLAPTPQLKERLAY 328
>ANR50_HUMAN (Q9ULJ7) Ankyrin repeat domain-containing protein 50| Length = 1375 Score = 65.9 bits (159), Expect = 8e-11 Identities = 34/97 (35%), Positives = 53/97 (54%) Frame = +3 Query: 264 LNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVREL 443 +N+ D R+ L AAW GHV VV+ L +H + A+Q+GH++VV+ L Sbjct: 951 VNAADNEKRSALQSAAWQGHVKVVQLLIEHGAVVDHTCNQGATALCIAAQEGHIDVVQVL 1010 Query: 444 LASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 L GA ++ G TA+ AA+N H +++K L + G Sbjct: 1011 LEHGADPNHADQFGRTAMRVAAKNGHSQIIKLLEKYG 1047 Score = 62.4 bits (150), Expect = 9e-10 Identities = 31/99 (31%), Positives = 53/99 (53%) Frame = +3 Query: 264 LNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVREL 443 + + D RT LH++ W GH+++V+ L + + A+ +GH++VV+ L Sbjct: 918 VEASDAEGRTALHVSCWQGHMEMVQVLIAYHADVNAADNEKRSALQSAAWQGHVKVVQLL 977 Query: 444 LASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVD 560 + GA V +G TAL AAQ H+++V+ L+ G D Sbjct: 978 IEHGAVVDHTCNQGATALCIAAQEGHIDVVQVLLEHGAD 1016 Score = 58.5 bits (140), Expect = 1e-08 Identities = 41/128 (32%), Positives = 57/128 (44%), Gaps = 5/128 (3%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 L AA G V +L + + ++ D SRT L AAW GH D+V L +H Sbjct: 561 LRSAAWGGHTEVVSALLYAG-VKVDCADADSRTALRAAAWGGHEDIVLNLLQHGAEVNKA 619 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFA-----AQNSHLELVKY 539 + A+ GH E+V LL GA V ++ G TAL A A H +V Sbjct: 620 DNEGRTALIAAAYMGHREIVEHLLDHGAEVNHEDVDGRTALSVAALCVPASKGHASVVSL 679 Query: 540 LVRRGVDI 563 L+ RG ++ Sbjct: 680 LIDRGAEV 687 Score = 57.0 bits (136), Expect = 4e-08 Identities = 39/118 (33%), Positives = 59/118 (50%) Frame = +3 Query: 207 ARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXX 386 A G A+ V L D ++ D+ TPL +AA+ GHVDVV L + Sbjct: 669 ASKGHASVVSLLIDRGA-EVDHCDKDGMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNG 727 Query: 387 XXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVD 560 + A+ GH VV LL GA+V + + +G T L A+ ++E+V+ L+ RG+D Sbjct: 728 RTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLD 785 Score = 55.1 bits (131), Expect = 1e-07 Identities = 34/123 (27%), Positives = 54/123 (43%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AA G E+L + N D R P LA+ GH D V+ L ++K Sbjct: 797 LHMAAFEGHRLICEALIEQGART-NEIDNDGRIPFILASQEGHYDCVQILLENKSNIDQR 855 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 + A+ +GH ++V L + GA V K+ G L+ A + L + +Y + G Sbjct: 856 GYDGRNALRVAALEGHRDIVELLFSHGADVNCKDADGRPTLYILALENQLTMAEYFLENG 915 Query: 555 VDI 563 ++ Sbjct: 916 ANV 918 Score = 54.3 bits (129), Expect = 2e-07 Identities = 34/112 (30%), Positives = 57/112 (50%) Frame = +3 Query: 228 AVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFA 407 ++ +L D+ ++N D RT L AA++G +DVV L + A Sbjct: 473 SIRTLLDNGA-SVNQCDSNGRTLLANAAYSGSLDVVNLLVSRGADLEIEDAHGHTPLTLA 531 Query: 408 SQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 +++GH +VV L+ GA++ ++ G+TAL AA H E+V L+ GV + Sbjct: 532 ARQGHTKVVNCLIGCGANINHTDQDGWTALRSAAWGGHTEVVSALLYAGVKV 583 Score = 50.8 bits (120), Expect = 3e-06 Identities = 31/120 (25%), Positives = 57/120 (47%) Frame = +3 Query: 204 AARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXX 383 A++ G V+ L ++ ++ R R L +AA GH D+V+ L H Sbjct: 833 ASQEGHYDCVQILLENKS-NIDQRGYDGRNALRVAALEGHRDIVELLFSHGADVNCKDAD 891 Query: 384 XXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 ++ + + L + L +GA+V+A + +G TALH + H+E+V+ L+ D+ Sbjct: 892 GRPTLYILALENQLTMAEYFLENGANVEASDAEGRTALHVSCWQGHMEMVQVLIAYHADV 951 Score = 50.8 bits (120), Expect = 3e-06 Identities = 36/117 (30%), Positives = 51/117 (43%) Frame = +3 Query: 204 AARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXX 383 AA G V+ L + ++ D RTPL AA GH VV L Sbjct: 701 AAYEGHVDVVDLLLEGGA-DVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAAVDSIDSE 759 Query: 384 XXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 + AS +G++EVVR LL G ++ G+T LH AA H + + L+ +G Sbjct: 760 GRTVLSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEGHRLICEALIEQG 816 Score = 37.0 bits (84), Expect = 0.039 Identities = 24/89 (26%), Positives = 42/89 (47%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 L AA G V+ L + + ++ ++ T L +AA GH+DVV+ L +H Sbjct: 962 LQSAAWQGHVKVVQLLIEHGAVVDHTCNQ-GATALCIAAQEGHIDVVQVLLEHGADPNHA 1020 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGAS 461 + A++ GH ++++ L GAS Sbjct: 1021 DQFGRTAMRVAAKNGHSQIIKLLEKYGAS 1049
>YL063_MIMIV (Q5UPE2) Putative ankyrin repeat protein L63| Length = 580 Score = 65.5 bits (158), Expect = 1e-10 Identities = 36/82 (43%), Positives = 51/82 (62%) Frame = +3 Query: 318 GHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTAL 497 GH++VVK L + FAS+KGHLEVV+ L++ GA+++AK+ + T Sbjct: 412 GHLEVVKYLVDQ---GANIRANNDRAVRFASRKGHLEVVKYLVSKGANIRAKDDRAVT-- 466 Query: 498 HFAAQNSHLELVKYLVRRGVDI 563 A+QN HLE+VKYLV +G DI Sbjct: 467 -LASQNGHLEVVKYLVSQGTDI 487 Score = 59.7 bits (143), Expect = 6e-09 Identities = 34/93 (36%), Positives = 54/93 (58%) Frame = +3 Query: 285 SRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASV 464 S + +A+ GH++VV+ L I +AS+ GHLEVV+ L+ GA++ Sbjct: 371 SNCAVTIASENGHIEVVRYLIS---LGADINSGNNYAIKYASENGHLEVVKYLVDQGANI 427 Query: 465 KAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 +A N + A+ FA++ HLE+VKYLV +G +I Sbjct: 428 RANNDR---AVRFASRKGHLEVVKYLVSKGANI 457 Score = 57.0 bits (136), Expect = 4e-08 Identities = 41/126 (32%), Positives = 63/126 (50%) Frame = +3 Query: 186 DLKLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXX 365 D + A+R G V+ L DR + LA+ GH++VVK L Sbjct: 432 DRAVRFASRKGHLEVVKYLVSKGANIRAKDDRA----VTLASQNGHLEVVKYLVSQ---G 484 Query: 366 XXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLV 545 + +AS+ GHLEVV+ L++ GA++KA + A+ +A+ N HLE+VK+LV Sbjct: 485 TDIKAGDDYAVRWASRNGHLEVVKYLISQGANIKADDD---YAVRWASLNGHLEVVKFLV 541 Query: 546 RRGVDI 563 + DI Sbjct: 542 NQNADI 547 Score = 55.8 bits (133), Expect = 8e-08 Identities = 35/86 (40%), Positives = 46/86 (53%) Frame = +3 Query: 306 AAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKG 485 AA GH+ VVK L I FAS+ GHLEVV L++ GA + A N Sbjct: 119 AAKNGHIGVVKYLVSK---GVNIGANDNCAIKFASENGHLEVVEYLVSKGADINANNN-- 173 Query: 486 FTALHFAAQNSHLELVKYLVRRGVDI 563 + A++N HL++V+YLV GVDI Sbjct: 174 -YPIEMASKNGHLKVVEYLVSLGVDI 198 Score = 45.4 bits (106), Expect = 1e-04 Identities = 20/58 (34%), Positives = 36/58 (62%) Frame = +3 Query: 396 IHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDITT 569 + A Q GHLE++R ++ G ++K + A+ A++N H+E+V+YL+ G DI + Sbjct: 345 VMLACQNGHLEIIRYFVSQGFNIKCGSN---CAVTIASENGHIEVVRYLISLGADINS 399 Score = 45.1 bits (105), Expect = 1e-04 Identities = 29/87 (33%), Positives = 45/87 (51%), Gaps = 3/87 (3%) Frame = +3 Query: 312 WA---GHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRK 482 WA GH++VVK L + +AS GHLEVV+ L+ A ++A N Sbjct: 497 WASRNGHLEVVKYLISQ---GANIKADDDYAVRWASLNGHLEVVKFLVNQNADIRAINN- 552 Query: 483 GFTALHFAAQNSHLELVKYLVRRGVDI 563 A+ +A +N H ++V+YL+ +G I Sbjct: 553 --YAVRWAHKNKHFDVVEYLISQGAVI 577 Score = 35.8 bits (81), Expect = 0.088 Identities = 17/50 (34%), Positives = 30/50 (60%) Frame = +3 Query: 414 KGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 +G L ++++L+ GAS + A+ A QN HLE+++Y V +G +I Sbjct: 325 EGDLSIIKDLILLGASERK-------AVMLACQNGHLEIIRYFVSQGFNI 367
>ANKS1_HUMAN (Q92625) Ankyrin repeat and SAM domain-containing protein 1A (Odin)| Length = 1133 Score = 65.1 bits (157), Expect = 1e-10 Identities = 43/124 (34%), Positives = 61/124 (49%), Gaps = 2/124 (1%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDP--LALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXX 368 LH AA GDA V L P +N ++ + T LH AA GH +VVK L + Sbjct: 116 LHLAAWKGDAQIVRLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPT 175 Query: 369 XXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVR 548 + A+ G LEVV+ LL + ++ + N K T LH AA+N H +V+ L+ Sbjct: 176 MRNNKFETPLDLAALYGRLEVVKMLLNAHPNLLSCNTKKHTPLHLAARNGHKAVVQVLLD 235 Query: 549 RGVD 560 G+D Sbjct: 236 AGMD 239 Score = 61.6 bits (148), Expect = 1e-09 Identities = 39/104 (37%), Positives = 51/104 (49%), Gaps = 3/104 (2%) Frame = +3 Query: 264 LNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVREL 443 +N D TPLH AA GH DVV+ L ++ +H A+ KG ++VR L Sbjct: 72 VNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIVRLL 131 Query: 444 LASGAS---VKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDIT 566 + G S V +N TALH AAQ H E+VK L+ D T Sbjct: 132 IHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPT 175 Score = 45.1 bits (105), Expect = 1e-04 Identities = 35/101 (34%), Positives = 47/101 (46%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 L AA G V+ L ++ P L+ + TPLHLAA GH VV+ L Sbjct: 185 LDLAALYGRLEVVKMLLNAHPNLLSCNTK-KHTPLHLAARNGHKAVVQVLLD-AGMDSNY 242 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTAL 497 +H A+ G +VV+ LLA+G V K+ G TAL Sbjct: 243 QTEMGSALHEAALFGKTDVVQILLAAGTDVNIKDNHGLTAL 283 Score = 30.0 bits (66), Expect = 4.8 Identities = 13/32 (40%), Positives = 20/32 (62%) Frame = +3 Query: 453 GASVKAKNRKGFTALHFAAQNSHLELVKYLVR 548 G +V + G+T LH AA N H ++V+ L+R Sbjct: 69 GPNVNCVDSTGYTPLHHAALNGHKDVVEVLLR 100
>YD58_SCHPO (Q10311) Hypothetical protein C6C3.08 in chromosome I| Length = 234 Score = 64.3 bits (155), Expect = 2e-10 Identities = 36/101 (35%), Positives = 50/101 (49%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AA G + V+ LCD P + +D +TPLH AA G + VVK L + Sbjct: 111 LHYAAGKGRLSIVQLLCDKAPELIRKKDLQGQTPLHRAAAVGKIQVVKYLISQRAPLNTS 170 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTAL 497 +HFA +GH +V EL+ +GA K+ + TAL Sbjct: 171 DSYGFTPLHFALAEGHPDVGVELVRAGADTLRKDSENHTAL 211 Score = 51.2 bits (121), Expect = 2e-06 Identities = 35/118 (29%), Positives = 53/118 (44%), Gaps = 1/118 (0%) Frame = +3 Query: 210 RSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLC-KHKXXXXXXXXXX 386 RS +E L + + R +T LH AA G + +V+ LC K Sbjct: 82 RSVPDNVIEELINRSDVDPTITTRGGQTCLHYAAGKGRLSIVQLLCDKAPELIRKKDLQG 141 Query: 387 XXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVD 560 +H A+ G ++VV+ L++ A + + GFT LHFA H ++ LVR G D Sbjct: 142 QTPLHRAAAVGKIQVVKYLISQRAPLNTSDSYGFTPLHFALAEGHPDVGVELVRAGAD 199 Score = 42.0 bits (97), Expect = 0.001 Identities = 38/152 (25%), Positives = 58/152 (38%), Gaps = 39/152 (25%) Frame = +3 Query: 231 VESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXX--------------- 365 VE +DP +LN+ D RTPLH A G V+ + L K Sbjct: 19 VEQAIQNDPNSLNAVDDDKRTPLHWACSVGKVNTIYFLLKQPNIKPDEKDEAGWTPLMIS 78 Query: 366 ----------------------XXXXXXXXXXIHFASQKGHLEVVRELLASGAS--VKAK 473 +H+A+ KG L +V +LL A ++ K Sbjct: 79 INNRSVPDNVIEELINRSDVDPTITTRGGQTCLHYAAGKGRLSIV-QLLCDKAPELIRKK 137 Query: 474 NRKGFTALHFAAQNSHLELVKYLVRRGVDITT 569 + +G T LH AA +++VKYL+ + + T Sbjct: 138 DLQGQTPLHRAAAVGKIQVVKYLISQRAPLNT 169
>MIB2_MOUSE (Q8R516) Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb| homolog 2) (Mind bomb-2) (Skeletrophin) (Dystrophin-like protein) (Dyslike) Length = 973 Score = 63.9 bits (154), Expect = 3e-10 Identities = 45/124 (36%), Positives = 63/124 (50%), Gaps = 4/124 (3%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLH--LAAWAGHVDVVKCLCKHKXXXX 368 LH A + G V+ LC+ +N D + TPLH ++A AG +V+ L + Sbjct: 551 LHVAVQRGFLEVVKILCERG-CDVNLPDAHADTPLHSAISAGAGASSIVEVLTEVPGIDV 609 Query: 369 XXXXXXXXXI-HFASQKGHLEVVRELLASGAS-VKAKNRKGFTALHFAAQNSHLELVKYL 542 + H AS KGH+ VR++LA V AK GFTALH AA N+H E+ + L Sbjct: 610 TATNSQGFTLLHHASLKGHVLAVRKILARARQLVDAKKEDGFTALHLAALNNHREVAQVL 669 Query: 543 VRRG 554 +R G Sbjct: 670 IREG 673 Score = 60.1 bits (144), Expect = 4e-09 Identities = 32/92 (34%), Positives = 48/92 (52%) Frame = +3 Query: 288 RTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVK 467 RT L +AA+ G V++V+ L + + +H+ + E R LL++G +V Sbjct: 482 RTALQVAAYLGQVELVRLLLQARASMDLPDDEGNTVLHYTAMGNQPEATRVLLSAGCAVD 541 Query: 468 AKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 A+N TALH A Q LE+VK L RG D+ Sbjct: 542 ARNGTRSTALHVAVQRGFLEVVKILCERGCDV 573 Score = 56.2 bits (134), Expect = 6e-08 Identities = 42/132 (31%), Positives = 60/132 (45%), Gaps = 4/132 (3%) Frame = +3 Query: 186 DLKLHKAARSGDAAA--VESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVV-KCLCKHK 356 D LH A +G A+ VE L + + + + + T LH A+ GHV V K L + + Sbjct: 581 DTPLHSAISAGAGASSIVEVLTEVPGIDVTATNSQGFTLLHHASLKGHVLAVRKILARAR 640 Query: 357 XXXXXXXXXXXXXIHFASQKGHLEVVRELLASG-ASVKAKNRKGFTALHFAAQNSHLELV 533 +H A+ H EV + L+ G V +NRK + LH A Q +HL LV Sbjct: 641 QLVDAKKEDGFTALHLAALNNHREVAQVLIREGRCDVNVRNRKLQSPLHLAVQQAHLGLV 700 Query: 534 KYLVRRGVDITT 569 LV G + T Sbjct: 701 PLLVDAGCSVNT 712 Score = 48.1 bits (113), Expect = 2e-05 Identities = 33/111 (29%), Positives = 51/111 (45%), Gaps = 1/111 (0%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKH-KXXXXX 371 LH A+ G AV + ++++ T LHLAA H +V + L + + Sbjct: 620 LHHASLKGHVLAVRKILARARQLVDAKKEDGFTALHLAALNNHREVAQVLIREGRCDVNV 679 Query: 372 XXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHL 524 +H A Q+ HL +V L+ +G SV ++ +G TALH A Q L Sbjct: 680 RNRKLQSPLHLAVQQAHLGLVPLLVDAGCSVNTEDEEGDTALHVALQRHQL 730 Score = 33.5 bits (75), Expect = 0.44 Identities = 33/127 (25%), Positives = 47/127 (37%), Gaps = 3/127 (2%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 L AA G V L + +++ D T LH A + + L Sbjct: 485 LQVAAYLGQVELVRLLLQARA-SMDLPDDEGNTVLHYTAMGNQPEATRVLLSAGCAVDAR 543 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFA--AQNSHLELVKYLVR 548 +H A Q+G LEVV+ L G V + T LH A A +V+ L Sbjct: 544 NGTRSTALHVAVQRGFLEVVKILCERGCDVNLPDAHADTPLHSAISAGAGASSIVEVLTE 603 Query: 549 -RGVDIT 566 G+D+T Sbjct: 604 VPGIDVT 610
>MIB2_RAT (Q68LP1) Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb| homolog 2) (RBSC-skeletrophin/dystrophin-like polypeptide) Length = 971 Score = 63.9 bits (154), Expect = 3e-10 Identities = 45/124 (36%), Positives = 63/124 (50%), Gaps = 4/124 (3%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLH--LAAWAGHVDVVKCLCKHKXXXX 368 LH A + G V+ LC+ +N D + TPLH ++A AG +V+ L + Sbjct: 549 LHVAVQRGFLEVVKILCEHG-CDVNLPDAHADTPLHSAISAGAGASSIVEVLTEVPGIDV 607 Query: 369 XXXXXXXXXI-HFASQKGHLEVVRELLASGAS-VKAKNRKGFTALHFAAQNSHLELVKYL 542 + H AS KGH+ VR++LA V AK GFTALH AA N+H E+ + L Sbjct: 608 TATNSQGFTLLHHASLKGHVLAVRKILARARQLVDAKKEDGFTALHLAALNNHREVAQVL 667 Query: 543 VRRG 554 +R G Sbjct: 668 IREG 671 Score = 57.8 bits (138), Expect = 2e-08 Identities = 31/92 (33%), Positives = 46/92 (50%) Frame = +3 Query: 288 RTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVK 467 RT L +AA+ G V++V+ L + + +H+ + E R LL++G V Sbjct: 480 RTALQVAAYLGQVELVRLLLQARASVDLLDEEGNTALHYTAMGNQPEATRLLLSAGCGVD 539 Query: 468 AKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 A+N TALH A Q LE+VK L G D+ Sbjct: 540 AQNGTRSTALHVAVQRGFLEVVKILCEHGCDV 571 Score = 56.6 bits (135), Expect = 5e-08 Identities = 42/132 (31%), Positives = 61/132 (46%), Gaps = 4/132 (3%) Frame = +3 Query: 186 DLKLHKAARSGDAAA--VESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVV-KCLCKHK 356 D LH A +G A+ VE L + + + + + T LH A+ GHV V K L + + Sbjct: 579 DTPLHSAISAGAGASSIVEVLTEVPGIDVTATNSQGFTLLHHASLKGHVLAVRKILARAR 638 Query: 357 XXXXXXXXXXXXXIHFASQKGHLEVVRELLASG-ASVKAKNRKGFTALHFAAQNSHLELV 533 +H A+ H EV + L+ G V +NRK + LH A Q +HL LV Sbjct: 639 QLVDAKKEDGFTALHLAALNNHREVAQVLIREGRCDVNVRNRKLQSPLHLAVQQAHLGLV 698 Query: 534 KYLVRRGVDITT 569 LV G ++ T Sbjct: 699 PLLVDAGCNVNT 710 Score = 47.0 bits (110), Expect = 4e-05 Identities = 32/111 (28%), Positives = 51/111 (45%), Gaps = 1/111 (0%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKH-KXXXXX 371 LH A+ G AV + ++++ T LHLAA H +V + L + + Sbjct: 618 LHHASLKGHVLAVRKILARARQLVDAKKEDGFTALHLAALNNHREVAQVLIREGRCDVNV 677 Query: 372 XXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHL 524 +H A Q+ HL +V L+ +G +V ++ +G TALH A Q L Sbjct: 678 RNRKLQSPLHLAVQQAHLGLVPLLVDAGCNVNTEDEEGDTALHVALQRHQL 728 Score = 33.9 bits (76), Expect = 0.33 Identities = 27/100 (27%), Positives = 37/100 (37%), Gaps = 3/100 (3%) Frame = +3 Query: 276 DRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASG 455 D T LH A + + L +H A Q+G LEVV+ L G Sbjct: 509 DEEGNTALHYTAMGNQPEATRLLLSAGCGVDAQNGTRSTALHVAVQRGFLEVVKILCEHG 568 Query: 456 ASVKAKNRKGFTALHFA--AQNSHLELVKYLVR-RGVDIT 566 V + T LH A A +V+ L G+D+T Sbjct: 569 CDVNLPDAHADTPLHSAISAGAGASSIVEVLTEVPGIDVT 608
>MIB2_HUMAN (Q96AX9) Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb| homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N) Length = 1013 Score = 63.9 bits (154), Expect = 3e-10 Identities = 45/124 (36%), Positives = 61/124 (49%), Gaps = 4/124 (3%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLH--LAAWAGHVDVVKCLCK-HKXXX 365 LH A + G V +LC+ +N D S TPLH ++A G +V+ L + Sbjct: 593 LHVAVQRGFLEVVRALCERG-CDVNLPDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDV 651 Query: 366 XXXXXXXXXXIHFASQKGHLEVVRELLASGAS-VKAKNRKGFTALHFAAQNSHLELVKYL 542 +H AS KGH VR++LA V AK GFTALH AA N+H E+ + L Sbjct: 652 TATNSQGFTLLHHASLKGHALAVRKILARARQLVDAKKEDGFTALHLAALNNHREVAQIL 711 Query: 543 VRRG 554 +R G Sbjct: 712 IREG 715 Score = 57.8 bits (138), Expect = 2e-08 Identities = 35/116 (30%), Positives = 58/116 (50%) Frame = +3 Query: 216 GDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXX 395 G+AA L P ++++++ RT L +AA+ G V++++ L + + Sbjct: 501 GNAARALDLLRRRPEQVDTKNQ-GRTALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTA 559 Query: 396 IHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 +H+A+ E R LL++G A N TALH A Q LE+V+ L RG D+ Sbjct: 560 LHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDV 615 Score = 51.6 bits (122), Expect = 2e-06 Identities = 39/130 (30%), Positives = 58/130 (44%), Gaps = 4/130 (3%) Frame = +3 Query: 186 DLKLHKAARSGDAAA--VESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVV-KCLCKHK 356 D LH A +G A+ VE L + + + + + T LH A+ GH V K L + + Sbjct: 623 DTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQGFTLLHHASLKGHALAVRKILARAR 682 Query: 357 XXXXXXXXXXXXXIHFASQKGHLEVVRELLASG-ASVKAKNRKGFTALHFAAQNSHLELV 533 +H A+ H EV + L+ G V +NRK + LH A Q +H+ LV Sbjct: 683 QLVDAKKEDGFTALHLAALNNHREVAQILIREGRCDVNVRNRKLQSPLHLAVQQAHVGLV 742 Query: 534 KYLVRRGVDI 563 LV G + Sbjct: 743 PLLVDAGCSV 752 Score = 50.1 bits (118), Expect = 4e-06 Identities = 34/111 (30%), Positives = 53/111 (47%), Gaps = 1/111 (0%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKH-KXXXXX 371 LH A+ G A AV + ++++ T LHLAA H +V + L + + Sbjct: 662 LHHASLKGHALAVRKILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGRCDVNV 721 Query: 372 XXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHL 524 +H A Q+ H+ +V L+ +G SV A++ +G TALH A Q L Sbjct: 722 RNRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEEGDTALHVALQRHQL 772 Score = 36.2 bits (82), Expect = 0.067 Identities = 23/77 (29%), Positives = 28/77 (36%) Frame = +3 Query: 276 DRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASG 455 D T LH AA + + L +H A Q+G LEVVR L G Sbjct: 553 DDEGNTALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERG 612 Query: 456 ASVKAKNRKGFTALHFA 506 V + T LH A Sbjct: 613 CDVNLPDAHSDTPLHSA 629
>MIB1_BRARE (Q804S5) Ubiquitin ligase protein mib (EC 6.3.2.-) (Mind bomb| protein) Length = 1030 Score = 63.5 bits (153), Expect = 4e-10 Identities = 40/121 (33%), Positives = 58/121 (47%) Frame = +3 Query: 192 KLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXX 371 +L KAA +GD A VE + + +N + T + A+ GHVDV+K L KH Sbjct: 434 ELVKAAANGDLAKVEDILKRPDVDVNGQCA-GHTAMQAASQNGHVDVLKLLLKHSVDLEA 492 Query: 372 XXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRR 551 +H AS V+ L GA + A+N++ T LH A HL++VK L+ Sbjct: 493 EDKDGDRAVHHASFGDEGSVIEVLHRGGADLNARNKRRQTPLHIAVNKGHLQVVKTLLDF 552 Query: 552 G 554 G Sbjct: 553 G 553 Score = 52.8 bits (125), Expect = 7e-07 Identities = 43/159 (27%), Positives = 63/159 (39%), Gaps = 36/159 (22%) Frame = +3 Query: 186 DLKLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXX 365 D +H A+ GD +V + LN+R++ +TPLH+A GH+ VVK L Sbjct: 498 DRAVHHAS-FGDEGSVIEVLHRGGADLNARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHP 556 Query: 366 XXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGF------------------- 488 +H A K +++ LL +GA V N GF Sbjct: 557 SLQDSEGDTPLHDAISKKRDDMLSVLLEAGADVTITNNNGFNALHHAALRGNPSAMRVLL 616 Query: 489 -----------------TALHFAAQNSHLELVKYLVRRG 554 TALH AA N+H+E+ + LV +G Sbjct: 617 SKLPRPWIVDEKKDDGYTALHLAALNNHVEVAELLVHQG 655 Score = 44.3 bits (103), Expect = 2e-04 Identities = 32/119 (26%), Positives = 55/119 (46%), Gaps = 3/119 (2%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDS--DPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKH-KXXX 365 LH AA G+ +A+ L P ++ + T LHLAA HV+V + L Sbjct: 600 LHHAALRGNPSAMRVLLSKLPRPWIVDEKKDDGYTALHLAALNNHVEVAELLVHQGNANL 659 Query: 366 XXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYL 542 +H A ++ H ++VR L+ + A + +++ G T LH A ++ L ++ L Sbjct: 660 DVQNVNQQTALHLAVERQHTQIVRLLVRAEAKLDVQDKDGDTPLHEALRHHTLSQLRQL 718 Score = 37.4 bits (85), Expect = 0.030 Identities = 19/52 (36%), Positives = 30/52 (57%), Gaps = 1/52 (1%) Frame = +3 Query: 396 IHFASQKGHLEVVRELLASG-ASVKAKNRKGFTALHFAAQNSHLELVKYLVR 548 +H A+ H+EV L+ G A++ +N TALH A + H ++V+ LVR Sbjct: 636 LHLAALNNHVEVAELLVHQGNANLDVQNVNQQTALHLAVERQHTQIVRLLVR 687 Score = 30.4 bits (67), Expect = 3.7 Identities = 16/53 (30%), Positives = 28/53 (52%) Frame = +3 Query: 405 ASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 A+ G L V ++L G TA+ A+QN H++++K L++ VD+ Sbjct: 438 AAANGDLAKVEDILKRPDVDVNGQCAGHTAMQAASQNGHVDVLKLLLKHSVDL 490
>TNI3K_PONPY (Q5RF15) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) Length = 617 Score = 62.8 bits (151), Expect = 7e-10 Identities = 38/125 (30%), Positives = 62/125 (49%), Gaps = 2/125 (1%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH A +G A + L +N +D + TPLH+AA+ GH V + L K Sbjct: 137 LHIATIAGHLEAADVLLQHGA-NVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVS 195 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASG--ASVKAKNRKGFTALHFAAQNSHLELVKYLVR 548 +H AS KG L + + L+ G A V A++ + LHF ++ H ++VKYL++ Sbjct: 196 GEVGDRPLHLASAKGFLNIAKLLMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLLQ 255 Query: 549 RGVDI 563 +++ Sbjct: 256 NDLEV 260 Score = 51.6 bits (122), Expect = 2e-06 Identities = 28/88 (31%), Positives = 38/88 (43%) Frame = +3 Query: 291 TPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKA 470 T LH+A AGH++ L +H +H A+ GH +V R LL GA V Sbjct: 135 TALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNV 194 Query: 471 KNRKGFTALHFAAQNSHLELVKYLVRRG 554 G LH A+ L + K L+ G Sbjct: 195 SGEVGDRPLHLASAKGFLNIAKLLMEEG 222 Score = 50.4 bits (119), Expect = 3e-06 Identities = 30/98 (30%), Positives = 47/98 (47%), Gaps = 3/98 (3%) Frame = +3 Query: 279 RLSR---TPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLA 449 RL+R T LHLA + + +++ L +H A+ GHLE LL Sbjct: 95 RLTRNGFTALHLAVYKDNAELITSLLHGGADIQQVGYGGLTALHIATIAGHLEAADVLLQ 154 Query: 450 SGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 GA+V ++ FT LH AA H ++ + L++ G D+ Sbjct: 155 HGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADV 192 Score = 42.0 bits (97), Expect = 0.001 Identities = 38/166 (22%), Positives = 62/166 (37%), Gaps = 40/166 (24%) Frame = +3 Query: 186 DLKLHKAARSGDAAAVESLCDSDPLA-LNSRDRLSRTPLHLAAWAGHVDVVKCLCKH--K 356 D LH A+ G + L + A +N++D PLH + GH D+VK L ++ + Sbjct: 200 DRPLHLASAKGFLNIAKLLMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLLQNDLE 259 Query: 357 XXXXXXXXXXXXXIHFASQKGHLEVVRELLA-SGA------------------------- 458 +H A G EV +E++ SG Sbjct: 260 VQPHVVNIYGDTPLHLACYNGKFEVAKEIIQISGTESLTKENIFSETAFHSACTYGKSID 319 Query: 459 -----------SVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 ++ + R G T LH A + H+ LV++L+ G D+ Sbjct: 320 LVKFLLDQNVININHQGRDGHTGLHSACYHGHIHLVQFLLDNGADM 365 Score = 36.2 bits (82), Expect = 0.067 Identities = 18/49 (36%), Positives = 24/49 (48%) Frame = +3 Query: 417 GHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 G+ +R L+ G R GFTALH A + EL+ L+ G DI Sbjct: 78 GNKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSLLHGGADI 126
>TNI3K_HUMAN (Q59H18) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 936 Score = 62.4 bits (150), Expect = 9e-10 Identities = 38/125 (30%), Positives = 62/125 (49%), Gaps = 2/125 (1%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH A +G A + L +N +D + TPLH+AA+ GH V + L K Sbjct: 239 LHIATIAGHLEAADVLLQHGA-NVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVS 297 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASG--ASVKAKNRKGFTALHFAAQNSHLELVKYLVR 548 +H AS KG L + + L+ G A V A++ + LHF ++ H ++VKYL++ Sbjct: 298 GEVGDRPLHLASAKGFLNIAKLLMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLLQ 357 Query: 549 RGVDI 563 +++ Sbjct: 358 SDLEV 362 Score = 51.6 bits (122), Expect = 2e-06 Identities = 28/88 (31%), Positives = 38/88 (43%) Frame = +3 Query: 291 TPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKA 470 T LH+A AGH++ L +H +H A+ GH +V R LL GA V Sbjct: 237 TALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNV 296 Query: 471 KNRKGFTALHFAAQNSHLELVKYLVRRG 554 G LH A+ L + K L+ G Sbjct: 297 SGEVGDRPLHLASAKGFLNIAKLLMEEG 324 Score = 50.8 bits (120), Expect = 3e-06 Identities = 30/98 (30%), Positives = 47/98 (47%), Gaps = 3/98 (3%) Frame = +3 Query: 279 RLSR---TPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLA 449 RL+R T LHLA + + +++ L +H A+ GHLE LL Sbjct: 197 RLTRNGFTALHLAVYKDNAELITSLLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQ 256 Query: 450 SGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 GA+V ++ FT LH AA H ++ + L++ G D+ Sbjct: 257 HGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADV 294 Score = 42.4 bits (98), Expect = 0.001 Identities = 37/131 (28%), Positives = 57/131 (43%), Gaps = 8/131 (6%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSD----PLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXX 362 LH +R G V+ L SD P +N TPLHLA + G +V K + + Sbjct: 340 LHFCSRFGHHDIVKYLLQSDLEVQPHVVNI---YGDTPLHLACYNGKFEVAKEIIQISGT 396 Query: 363 XXXXXXX--XXXXIHFASQKGH-LEVVRELLASGA-SVKAKNRKGFTALHFAAQNSHLEL 530 H A G +++V+ LL ++ + R G T LH A + H+ L Sbjct: 397 ESLTKENIFSETAFHSACTYGKSIDLVKFLLDQNVININHQGRDGHTGLHSACYHGHIRL 456 Query: 531 VKYLVRRGVDI 563 V++L+ G D+ Sbjct: 457 VQFLLDNGADM 467 Score = 35.8 bits (81), Expect = 0.088 Identities = 17/44 (38%), Positives = 22/44 (50%) Frame = +3 Query: 432 VRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 +R L+ G R GFTALH A + EL+ L+ G DI Sbjct: 185 IRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSLLHSGADI 228
>ANKR6_HUMAN (Q9Y2G4) Ankyrin repeat domain-containing protein 6| Length = 692 Score = 62.4 bits (150), Expect = 9e-10 Identities = 36/117 (30%), Positives = 55/117 (47%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH+A G+ + +L + AL+ +D+ T LH A+W G K L K Sbjct: 79 LHRATVVGNTEIIAALIH-EGCALDRQDKDGNTALHEASWHGFSQSAKLLVKAGANVLAK 137 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLV 545 +H A Q H + R LL +G+ KN G T LH AA+ +HL +++ L+ Sbjct: 138 NKAGNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSIIRLLL 194 Score = 59.3 bits (142), Expect = 7e-09 Identities = 40/124 (32%), Positives = 58/124 (46%), Gaps = 4/124 (3%) Frame = +3 Query: 195 LHKAARSGDAAAVESL----CDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXX 362 LH AA G V+ L CD L+ +D +T LH A G+ +++ L Sbjct: 46 LHLAANKGHLPVVQILLKAGCD-----LDVQDDGDQTALHRATVVGNTEIIAALIHEGCA 100 Query: 363 XXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYL 542 +H AS G + + L+ +GA+V AKN+ G TALH A QNSH + + L Sbjct: 101 LDRQDKDGNTALHEASWHGFSQSAKLLVKAGANVLAKNKAGNTALHLACQNSHSQSTRVL 160 Query: 543 VRRG 554 + G Sbjct: 161 LLAG 164 Score = 58.5 bits (140), Expect = 1e-08 Identities = 37/124 (29%), Positives = 59/124 (47%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH+A+ G + + + L + L ++++ T LHLA H + L Sbjct: 112 LHEASWHGFSQSAKLLVKAGANVL-AKNKAGNTALHLACQNSHSQSTRVLLLAGSRADLK 170 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 +H A++ HL ++R LL + SV KN+ G TALH AA +H ++ K L+ G Sbjct: 171 NNAGDTCLHVAARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAKILLEAG 230 Query: 555 VDIT 566 D T Sbjct: 231 ADTT 234 Score = 55.1 bits (131), Expect = 1e-07 Identities = 30/92 (32%), Positives = 49/92 (53%) Frame = +3 Query: 288 RTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVK 467 RTPLHLAA GH+ VV+ L K +H A+ G+ E++ L+ G ++ Sbjct: 43 RTPLHLAANKGHLPVVQILLKAGCDLDVQDDGDQTALHRATVVGNTEIIAALIHEGCALD 102 Query: 468 AKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 +++ G TALH A+ + + K LV+ G ++ Sbjct: 103 RQDKDGNTALHEASWHGFSQSAKLLVKAGANV 134 Score = 38.9 bits (89), Expect = 0.010 Identities = 22/53 (41%), Positives = 31/53 (58%) Frame = +3 Query: 405 ASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 A+ KG E V +L+ GA V A + G T LH AA HL +V+ L++ G D+ Sbjct: 17 AAYKGQTENVVQLINKGARV-AVTKHGRTPLHLAANKGHLPVVQILLKAGCDL 68
>EHMT2_HUMAN (Q96KQ7) Histone-lysine N-methyltransferase, H3 lysine-9 specific 3| (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a) Length = 1210 Score = 62.4 bits (150), Expect = 9e-10 Identities = 37/125 (29%), Positives = 67/125 (53%), Gaps = 1/125 (0%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AA+ G L + +N+ D+ RTPL A H++V + + + Sbjct: 689 LHAAAQKGSVEICHVLLQAGA-NINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSK 747 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASG-ASVKAKNRKGFTALHFAAQNSHLELVKYLVRR 551 +H A++ G+LE+V LL++G V A++ G+T + +AA++ H+E+++ L+ R Sbjct: 748 EEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTR 807 Query: 552 GVDIT 566 G D+T Sbjct: 808 GADVT 812 Score = 53.5 bits (127), Expect = 4e-07 Identities = 34/122 (27%), Positives = 56/122 (45%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AA+ G+ V L + + +N++D TP+ AA H++V++ L Sbjct: 755 LHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLT 814 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 +H+AS G + LL + + A N G T LH AA+ S+ + V + RG Sbjct: 815 DNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRG 874 Query: 555 VD 560 + Sbjct: 875 AN 876 Score = 50.8 bits (120), Expect = 3e-06 Identities = 38/126 (30%), Positives = 57/126 (45%), Gaps = 2/126 (1%) Frame = +3 Query: 192 KLHKAARSGDAAAVE-SLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXX 368 +L+ + + G+ V L D+ S + RTPLH AA G V++ L + Sbjct: 653 QLYLSVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANIN 712 Query: 369 XXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVR 548 + A HLEV R ++ G V +K G T LH AA+ +LE+V L+ Sbjct: 713 AVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLS 772 Query: 549 RG-VDI 563 G VD+ Sbjct: 773 TGQVDV 778 Score = 34.7 bits (78), Expect = 0.20 Identities = 25/99 (25%), Positives = 45/99 (45%), Gaps = 1/99 (1%) Frame = +3 Query: 270 SRDRLSRTPLHLAAWAGHVDVVKCLCKH-KXXXXXXXXXXXXXIHFASQKGHLEVVRELL 446 S++ T LH AA G++++V L + I +A++ H+EV+R LL Sbjct: 746 SKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLL 805 Query: 447 ASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 GA V + + LH+A+ + + L+ D+ Sbjct: 806 TRGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDL 844
>LATA_LATMA (P23631) Alpha-latrotoxin precursor (Alpha-LTX)| Length = 1401 Score = 62.4 bits (150), Expect = 9e-10 Identities = 34/117 (29%), Positives = 57/117 (48%) Frame = +3 Query: 189 LKLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXX 368 + +H AA +G +++ D ++ D+ S TPL+LAA H+DV+K Sbjct: 831 MPIHGAAMTGLLDVAQAIISIDATVVDIEDKNSDTPLNLAAQNSHIDVIKYFIDQGADIN 890 Query: 369 XXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKY 539 + S+KG+L++V+ L A+V + G ++A QN HL +VKY Sbjct: 891 TRNKKGLAPLLAFSKKGNLDMVKYLFDKNANVYIADNDGMNFFYYAVQNGHLNIVKY 947 Score = 57.8 bits (138), Expect = 2e-08 Identities = 32/89 (35%), Positives = 49/89 (55%) Frame = +3 Query: 294 PLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAK 473 PLH AA GH+D+VK L + + + +AS+ GH VV+ L+++GA V Sbjct: 1007 PLHQAARYGHLDIVKYLVEEEFLSVDGSKTDTP-LCYASENGHFTVVQYLVSNGAKVNHD 1065 Query: 474 NRKGFTALHFAAQNSHLELVKYLVRRGVD 560 G TA+ A +HL++V++L GVD Sbjct: 1066 CGNGMTAIDKAITKNHLQVVQFLAANGVD 1094 Score = 57.8 bits (138), Expect = 2e-08 Identities = 37/126 (29%), Positives = 61/126 (48%), Gaps = 1/126 (0%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AA S ++ L D ++ TPLHLA + G L ++ Sbjct: 767 LHLAAMSKYPELIQILLDQGS-NFEAKTNSGATPLHLATFKGKSQAALILLNNEVNWRDT 825 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASV-KAKNRKGFTALHFAAQNSHLELVKYLVRR 551 IH A+ G L+V + +++ A+V +++ T L+ AAQNSH++++KY + + Sbjct: 826 DENGQMPIHGAAMTGLLDVAQAIISIDATVVDIEDKNSDTPLNLAAQNSHIDVIKYFIDQ 885 Query: 552 GVDITT 569 G DI T Sbjct: 886 GADINT 891 Score = 53.5 bits (127), Expect = 4e-07 Identities = 37/118 (31%), Positives = 57/118 (48%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH+AAR G V+ L + + L+++ + TPL A+ GH VV+ L + Sbjct: 1008 LHQAARYGHLDIVKYLVEEEFLSVDGSK--TDTPLCYASENGHFTVVQYLVSNGAKVNHD 1065 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVR 548 I A K HL+VV+ L A+G + KN +G T A + L + +YL+R Sbjct: 1066 CGNGMTAIDKAITKNHLQVVQFLAANGVDFRRKNSRGTTPFLTAVAENALHIAEYLIR 1123 Score = 49.3 bits (116), Expect = 8e-06 Identities = 29/124 (23%), Positives = 58/124 (46%), Gaps = 1/124 (0%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH A G + A L +++ + D + P+H AA G +DV + + Sbjct: 800 LHLATFKGKSQAALILLNNE-VNWRDTDENGQMPIHGAAMTGLLDVAQAIISIDATVVDI 858 Query: 375 XXXXXXX-IHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRR 551 ++ A+Q H++V++ + GA + +N+KG L ++ +L++VKYL + Sbjct: 859 EDKNSDTPLNLAAQNSHIDVIKYFIDQGADINTRNKKGLAPLLAFSKKGNLDMVKYLFDK 918 Query: 552 GVDI 563 ++ Sbjct: 919 NANV 922 Score = 48.1 bits (113), Expect = 2e-05 Identities = 32/125 (25%), Positives = 60/125 (48%), Gaps = 3/125 (2%) Frame = +3 Query: 198 HKAARSGDAAAVESLCD-SDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 H AA+SG+ + L + LN D+ TP+H+AA +G+ +V L + Sbjct: 496 HAAAKSGNDKIMFGLTFLAKSTELNQPDKKGYTPIHVAADSGNAGIVNLLIQRGVSINSK 555 Query: 375 XXXXXXX-IHFASQKGHLEVVRELLAS-GASVKAKNRKGFTALHFAAQNSHLELVKYLVR 548 +H A+Q+G + + L+ S ++ +++ GFT LH+A + L +L + Sbjct: 556 TYHFLQTPLHLAAQRGFVTTFQRLMESPEININERDKDGFTPLHYAIRGGERILEAFLNQ 615 Query: 549 RGVDI 563 +D+ Sbjct: 616 ISIDV 620 Score = 47.4 bits (111), Expect = 3e-05 Identities = 35/118 (29%), Positives = 48/118 (40%), Gaps = 1/118 (0%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AA+ G + L +S + +N RD+ TPLH A G + L + Sbjct: 564 LHLAAQRGFVTTFQRLMESPEININERDKDGFTPLHYAIRGGERILEAFLNQISIDVNAK 623 Query: 375 XXXXXXXIHFASQKGHLEVVRELLAS-GASVKAKNRKGFTALHFAAQNSHLELVKYLV 545 H A K V LL S + A + TALH+AA +LE K L+ Sbjct: 624 SNTGLTPFHLAIIKNDWPVASTLLGSKKVDINAVDENNITALHYAAILGYLETTKQLI 681 Score = 36.6 bits (83), Expect = 0.051 Identities = 18/59 (30%), Positives = 35/59 (59%), Gaps = 2/59 (3%) Frame = +3 Query: 399 HFASQKGHLEVVREL--LASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDITT 569 H A++ G+ +++ L LA + ++KG+T +H AA + + +V L++RGV I + Sbjct: 496 HAAAKSGNDKIMFGLTFLAKSTELNQPDKKGYTPIHVAADSGNAGIVNLLIQRGVSINS 554 Score = 34.3 bits (77), Expect = 0.26 Identities = 21/87 (24%), Positives = 39/87 (44%), Gaps = 1/87 (1%) Frame = +3 Query: 297 LHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXX-IHFASQKGHLEVVRELLASGASVKAK 473 LH A H DV L + +H A +G +++ + G +++ K Sbjct: 700 LHYAILYKHDDVASFLMRSSNVNVNLKALGGITPLHLAVIQGRKQILSLMFDIGVNIEQK 759 Query: 474 NRKGFTALHFAAQNSHLELVKYLVRRG 554 + +T LH AA + + EL++ L+ +G Sbjct: 760 TDEKYTPLHLAAMSKYPELIQILLDQG 786
>ANKK1_MOUSE (Q8BZ25) Ankyrin repeat and protein kinase domain-containing| protein 1 (EC 2.7.11.1) Length = 745 Score = 62.4 bits (150), Expect = 9e-10 Identities = 39/123 (31%), Positives = 60/123 (48%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AA G V+ L L+++ R RTPLHLA G V ++ L K Sbjct: 506 LHVAAYFGHIGLVK-LLSGQGAELDAQQRNLRTPLHLAVERGKVRAIQHLLKCGALPDAL 564 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 +H A+ +G + + LL GAS++ + ++G+T LH A HLE++ L + Sbjct: 565 DHSGYSPLHIAAARGKDLIFKMLLRYGASLELRTQQGWTPLHLATYKGHLEIIHQLAKSH 624 Query: 555 VDI 563 VD+ Sbjct: 625 VDL 627 Score = 58.5 bits (140), Expect = 1e-08 Identities = 36/120 (30%), Positives = 58/120 (48%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AA++GD L D L +N+R+ TPLHLAA +V + L + Sbjct: 440 LHFAAQNGDDHTARLLLDHGAL-VNAREHEGWTPLHLAAQNNFENVARLLVSRQADLSPH 498 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 +H A+ GH+ +V+ L GA + A+ R T LH A + + +++L++ G Sbjct: 499 EAEGKTPLHVAAYFGHIGLVKLLSGQGAELDAQQRNLRTPLHLAVERGKVRAIQHLLKCG 558 Score = 53.9 bits (128), Expect = 3e-07 Identities = 37/124 (29%), Positives = 53/124 (42%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH G V L D + ++ + TPL +A D+ L H Sbjct: 374 LHFLVAGGSLEQVRLLLSHD-VDVDCQTASGYTPLLIATQDQQPDLCALLLAHGADTNLA 432 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 +HFA+Q G R LL GA V A+ +G+T LH AAQN+ + + LV R Sbjct: 433 DEDGWAPLHFAAQNGDDHTARLLLDHGALVNAREHEGWTPLHLAAQNNFENVARLLVSRQ 492 Query: 555 VDIT 566 D++ Sbjct: 493 ADLS 496 Score = 53.1 bits (126), Expect = 5e-07 Identities = 30/101 (29%), Positives = 47/101 (46%) Frame = +3 Query: 261 ALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRE 440 +L R + TPLHLA + GH++++ L K +H A+ +G V+ Sbjct: 593 SLELRTQQGWTPLHLATYKGHLEIIHQLAKSHVDLDALGSMQWTPLHLAAFQGEEGVMLA 652 Query: 441 LLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 LL GA+ A + G+T LH A + +L+ G DI Sbjct: 653 LLQCGANPNAAEQSGWTPLHLAVHKGTFLGITHLLEYGADI 693 Score = 52.4 bits (124), Expect = 9e-07 Identities = 35/123 (28%), Positives = 53/123 (43%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH A G + L S + L++ + TPLHLAA+ G V+ L + Sbjct: 605 LHLATYKGHLEIIHQLAKSH-VDLDALGSMQWTPLHLAAFQGEEGVMLALLQCGANPNAA 663 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 +H A KG + LL GA + A N+ G+T H AA + ++K LV+ Sbjct: 664 EQSGWTPLHLAVHKGTFLGITHLLEYGADIHACNKVGWTPAHLAALKGNTAILKVLVKAA 723 Query: 555 VDI 563 + Sbjct: 724 AQV 726 Score = 51.2 bits (121), Expect = 2e-06 Identities = 34/107 (31%), Positives = 49/107 (45%), Gaps = 2/107 (1%) Frame = +3 Query: 195 LHKAARSGDAAAVESL--CDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXX 368 LH A G A++ L C + P AL D +PLH+AA G + K L ++ Sbjct: 539 LHLAVERGKVRAIQHLLKCGALPDAL---DHSGYSPLHIAAARGKDLIFKMLLRYGASLE 595 Query: 369 XXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAA 509 +H A+ KGHLE++ +L S + A +T LH AA Sbjct: 596 LRTQQGWTPLHLATYKGHLEIIHQLAKSHVDLDALGSMQWTPLHLAA 642 Score = 44.7 bits (104), Expect = 2e-04 Identities = 29/99 (29%), Positives = 40/99 (40%) Frame = +3 Query: 267 NSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELL 446 N D PLH AA G + L H +H A+Q V R L+ Sbjct: 430 NLADEDGWAPLHFAAQNGDDHTARLLLDHGALVNAREHEGWTPLHLAAQNNFENVARLLV 489 Query: 447 ASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 + A + +G T LH AA H+ LVK L +G ++ Sbjct: 490 SRQADLSPHEAEGKTPLHVAAYFGHIGLVKLLSGQGAEL 528 Score = 42.7 bits (99), Expect = 7e-04 Identities = 29/105 (27%), Positives = 41/105 (39%) Frame = +3 Query: 240 LCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKG 419 L DS L + TPLH G ++ V+ L H + A+Q Sbjct: 355 LSDSKSLVASDVYENRVTPLHFLVAGGSLEQVRLLLSHDVDVDCQTASGYTPLLIATQDQ 414 Query: 420 HLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 ++ LLA GA + G+ LHFAAQN + L+ G Sbjct: 415 QPDLCALLLAHGADTNLADEDGWAPLHFAAQNGDDHTARLLLDHG 459 Score = 35.8 bits (81), Expect = 0.088 Identities = 28/106 (26%), Positives = 46/106 (43%), Gaps = 2/106 (1%) Frame = +3 Query: 195 LHKAARSGDAAAVESL--CDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXX 368 LH AA G+ + +L C ++P N+ ++ TPLHLA G + L ++ Sbjct: 638 LHLAAFQGEEGVMLALLQCGANP---NAAEQSGWTPLHLAVHKGTFLGITHLLEYGADIH 694 Query: 369 XXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFA 506 H A+ KG+ +++ L+ + A V K T L A Sbjct: 695 ACNKVGWTPAHLAALKGNTAILKVLVKAAAQVDVKGGVSCTPLQLA 740
>TRPA1_CAEEL (Q18297) Transient receptor potential cation channel subfamily A| member 1 homolog Length = 1193 Score = 62.0 bits (149), Expect = 1e-09 Identities = 40/126 (31%), Positives = 61/126 (48%), Gaps = 5/126 (3%) Frame = +3 Query: 198 HKAARSGDAAAVESLCDSDPL----ALNSRDRLSRTPLHLAAWAGHVDVVKCLCK-HKXX 362 H A G+ +E + D DP+ ALN + +TPL +A H + +K + + K Sbjct: 227 HIVALRGEPEYLEMMMDHDPVEAIKALNLFNNEKKTPLRMAVEGNHPETLKKILQMEKKN 286 Query: 363 XXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYL 542 IHFA++KG LEV++ L+ +G + N LH AAQ + LE+V YL Sbjct: 287 SCKWMDREKELIHFAAEKGFLEVLKALVEAGGNKNELNEVKAVPLHVAAQMNQLEVVSYL 346 Query: 543 VRRGVD 560 + D Sbjct: 347 IEEEKD 352 Score = 59.3 bits (142), Expect = 7e-09 Identities = 38/123 (30%), Positives = 56/123 (45%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH+AA G AV L + D L +D + + LHLAA +GH K L + Sbjct: 493 LHRAAIGGQTGAVRQLLEWDIRLLLMKDEMGNSALHLAARSGHDATTKVLLDNGADKEAK 552 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 + A G LE + L+A GA +++ + T LH AA + +V+Y + G Sbjct: 553 NSYQKTPLQVAVDSGKLETCQRLVAKGAQIESSSDTK-TVLHTAAFYGNESIVRYFIAEG 611 Query: 555 VDI 563 V I Sbjct: 612 VTI 614 Score = 52.0 bits (123), Expect = 1e-06 Identities = 35/147 (23%), Positives = 60/147 (40%), Gaps = 24/147 (16%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 +H++AR G+ A++ PLA+N++D TPLH AA G+ D VK L Sbjct: 36 IHQSAREGNVNALQEALLKAPLAVNAQDGDFMTPLHYAARYGNYDAVKLLLSKNALPNTK 95 Query: 375 XXXXXXXIHFASQ------------------------KGHLEVVRELLASGASVKAKNRK 482 +H AS+ +++ L++ A + N+ Sbjct: 96 NREGDTPLHIASKYIYGYSDICSIIDEDQADSARKYNTATKKIINALVSENAEIDPVNKY 155 Query: 483 GFTALHFAAQNSHLELVKYLVRRGVDI 563 T LH+AA S+ + L++ D+ Sbjct: 156 QLTPLHYAAMKSNFSALHALIKLKADV 182 Score = 49.3 bits (116), Expect = 8e-06 Identities = 34/116 (29%), Positives = 56/116 (48%), Gaps = 2/116 (1%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDS--DPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXX 368 LH AARSG A + L D+ D A NS +TPL +A +G ++ + L K Sbjct: 527 LHLAARSGHDATTKVLLDNGADKEAKNS---YQKTPLQVAVDSGKLETCQRLVA-KGAQI 582 Query: 369 XXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVK 536 +H A+ G+ +VR +A G ++ ++ +G TA A +N H ++ + Sbjct: 583 ESSSDTKTVLHTAAFYGNESIVRYFIAEGVTIDRRDEEGKTAFDIACENDHKDVAR 638 Score = 48.5 bits (114), Expect = 1e-05 Identities = 30/100 (30%), Positives = 48/100 (48%), Gaps = 1/100 (1%) Frame = +3 Query: 264 LNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVREL 443 +N DR TP+H+ A G++++++ L KH +H A+ G VR+L Sbjct: 449 VNMVDRDQNTPMHIVASNGYLEMMQLLQKHGASITQVNEDEETALHRAAIGGQTGAVRQL 508 Query: 444 LASGAS-VKAKNRKGFTALHFAAQNSHLELVKYLVRRGVD 560 L + K+ G +ALH AA++ H K L+ G D Sbjct: 509 LEWDIRLLLMKDEMGNSALHLAARSGHDATTKVLLDNGAD 548
>RN5A_MOUSE (Q05921) 2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent| RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4) Length = 735 Score = 62.0 bits (149), Expect = 1e-09 Identities = 38/126 (30%), Positives = 57/126 (45%) Frame = +3 Query: 186 DLKLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXX 365 D L KA + GD V+ L + A D TPLH A AG VD+V L H Sbjct: 26 DSSLIKAVQKGDVVRVQQLLEKGADANACEDTWGWTPLHNAVQAGRVDIVNLLLSHGADP 85 Query: 366 XXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLV 545 A +G ++++ LL+ GA V + GFTA AA+ + E +++L Sbjct: 86 HRRKKNGATPFIIAGIQGDVKLLEILLSCGADVNECDENGFTAFMEAAERGNAEALRFLF 145 Query: 546 RRGVDI 563 +G ++ Sbjct: 146 AKGANV 151 Score = 35.0 bits (79), Expect = 0.15 Identities = 30/127 (23%), Positives = 54/127 (42%), Gaps = 5/127 (3%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPL--HLAAW--AGHVDVVKCLCKHKXX 362 L AA G + L + +++RD + R L L W ++ L +H Sbjct: 172 LMSAAEKGHLEVLRILLNDMKAEVDARDNMGRNALIRTLLNWDCENVEEITSILIQHGAD 231 Query: 363 XXXXXXXXXXXIHFASQKGHLEVVRELLA-SGASVKAKNRKGFTALHFAAQNSHLELVKY 539 + A ++ H +V+ LL+ G ++ A++ +G TAL A E+V+ Sbjct: 232 VNVRGERGKTPLIAAVERKHTGLVQMLLSREGINIDARDNEGKTALLIAVDKQLKEIVQL 291 Query: 540 LVRRGVD 560 L+ +G D Sbjct: 292 LLEKGAD 298
>MIB1_XENLA (Q6GNY1) Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb| homolog 1) Length = 1011 Score = 62.0 bits (149), Expect = 1e-09 Identities = 37/118 (31%), Positives = 57/118 (48%) Frame = +3 Query: 192 KLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXX 371 +L KAA +GD A V+ L + +N + T + A+ GHVD++K L KH Sbjct: 434 ELVKAAANGDVAKVDDLLKRQDVDVNGQCA-GHTAMQAASQNGHVDILKLLLKHSVDVEA 492 Query: 372 XXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLV 545 +H A+ V+ L GA + A+N++ T LH A HL++VK L+ Sbjct: 493 EDKDGDRAVHHAAFGDEGTVIEVLQRGGADLNARNKRRQTPLHIAVNKGHLQVVKKLL 550 Score = 54.7 bits (130), Expect = 2e-07 Identities = 44/159 (27%), Positives = 62/159 (38%), Gaps = 36/159 (22%) Frame = +3 Query: 186 DLKLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXX 365 D +H AA GD V + LN+R++ +TPLH+A GH+ VVK L Sbjct: 498 DRAVHHAA-FGDEGTVIEVLQRGGADLNARNKRRQTPLHIAVNKGHLQVVKKLLDFSCHP 556 Query: 366 XXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGF------------------- 488 +H A K +++ LL +GA V N GF Sbjct: 557 SLQDSEGDTPLHDAISKKRDDILAVLLEAGADVTITNNNGFNALHHAALRGNPSAMRVLL 616 Query: 489 -----------------TALHFAAQNSHLELVKYLVRRG 554 TALH AA N+H+E+ + LV +G Sbjct: 617 SKLPRPWIVDEKKDDGYTALHLAALNNHVEVAELLVHQG 655 Score = 43.9 bits (102), Expect = 3e-04 Identities = 32/119 (26%), Positives = 55/119 (46%), Gaps = 3/119 (2%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDS--DPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKH-KXXX 365 LH AA G+ +A+ L P ++ + T LHLAA HV+V + L Sbjct: 600 LHHAALRGNPSAMRVLLSKLPRPWIVDEKKDDGYTALHLAALNNHVEVAELLVHQGSANL 659 Query: 366 XXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYL 542 +H A ++ H ++VR L+ + A + +++ G T LH A ++ L ++ L Sbjct: 660 DIQNVNQQTALHLAVERQHTQIVRLLVRAEAKLDIQDKDGDTPLHEALRHHTLSQLRQL 718 Score = 40.4 bits (93), Expect = 0.004 Identities = 25/86 (29%), Positives = 41/86 (47%) Frame = +3 Query: 306 AAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKG 485 AA G V V L K + + ASQ GH+++++ LL V+A+++ G Sbjct: 438 AAANGDVAKVDDLLKRQDVDVNGQCAGHTAMQAASQNGHVDILKLLLKHSVDVEAEDKDG 497 Query: 486 FTALHFAAQNSHLELVKYLVRRGVDI 563 A+H AA +++ L R G D+ Sbjct: 498 DRAVHHAAFGDEGTVIEVLQRGGADL 523 Score = 37.0 bits (84), Expect = 0.039 Identities = 19/52 (36%), Positives = 30/52 (57%), Gaps = 1/52 (1%) Frame = +3 Query: 396 IHFASQKGHLEVVRELLASG-ASVKAKNRKGFTALHFAAQNSHLELVKYLVR 548 +H A+ H+EV L+ G A++ +N TALH A + H ++V+ LVR Sbjct: 636 LHLAALNNHVEVAELLVHQGSANLDIQNVNQQTALHLAVERQHTQIVRLLVR 687
>FEM1_CAEEL (P17221) Sex-determining protein fem-1 (Feminization of XX and XO| animals protein 1) Length = 656 Score = 61.6 bits (148), Expect = 1e-09 Identities = 37/120 (30%), Positives = 59/120 (49%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 L A+ +G V+ L + +N TPL A + GH+D+VK L + Sbjct: 93 LWAASAAGHIEIVKLLIEKANADVNQATNTRSTPLRGACYDGHLDIVKYLLEKGADPHIP 152 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 + AS + + +V ELL +G V K +G TALH AA++ ++E+VK L++ G Sbjct: 153 NRHGHTCLMIASYRNKVGIVEELLKTGIDVNKKTERGNTALHDAAESGNVEVVKILLKHG 212 Score = 42.7 bits (99), Expect = 7e-04 Identities = 39/135 (28%), Positives = 58/135 (42%), Gaps = 21/135 (15%) Frame = +3 Query: 219 DAAAVESLCDSDPLALNSR------------DRLSRTPLHLAAWAGHVDVVKCLCKHKXX 362 +AAAV +L +NSR D+ R PL +AA GH +VV+ L + Sbjct: 14 NAAAVGNLQRIKVFTINSRNDRQWIIDCFNSDQDGRYPLVIAARNGHANVVEYLLEIGAD 73 Query: 363 XXXXXXXXXXXIHF--------ASQKGHLEVVRELLA-SGASVKAKNRKGFTALHFAAQN 515 + AS GH+E+V+ L+ + A V T L A + Sbjct: 74 PSVRGVVEFDNENIQGTPPLWAASAAGHIEIVKLLIEKANADVNQATNTRSTPLRGACYD 133 Query: 516 SHLELVKYLVRRGVD 560 HL++VKYL+ +G D Sbjct: 134 GHLDIVKYLLEKGAD 148
>PSD10_RAT (Q9Z2X3) 26S proteasome non-ATPase regulatory subunit 10 (26S| proteasome regulatory subunit p28) (Gankyrin) Length = 231 Score = 61.2 bits (147), Expect = 2e-09 Identities = 38/109 (34%), Positives = 55/109 (50%) Frame = +3 Query: 234 ESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQ 413 ES+ LA + D+ SRT LH A AGH ++V+ L + +H A+ Sbjct: 24 ESILADKSLATRT-DQDSRTALHWACSAGHTEIVEFLLQLGVPVNEKDDAGWSPLHIAAS 82 Query: 414 KGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVD 560 G E+V+ LL GA V A N+ G TALH+AA + E+ L+ G + Sbjct: 83 AGRDEIVKALLIKGAQVNAVNQNGCTALHYAASKNRHEIAVMLLEGGAN 131 Score = 45.8 bits (107), Expect = 8e-05 Identities = 40/156 (25%), Positives = 59/156 (37%), Gaps = 33/156 (21%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH A +G VE L + +N +D +PLH+AA AG ++VK L Sbjct: 44 LHWACSAGHTEIVEFLLQLG-VPVNEKDDAGWSPLHIAASAGRDEIVKALLIKGAQVNAV 102 Query: 375 XXXXXXXIHFASQ---------------------------------KGHLEVVRELLASG 455 +H+A+ KG+L++V LL Sbjct: 103 NQNGCTALHYAASKNRHEIAVMLLEGGANPDAKNHYDATAMHRAAAKGNLKMVHILLFYK 162 Query: 456 ASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 AS ++ +G T LH A +E K LV +G I Sbjct: 163 ASTNIQDTEGNTPLHLACDEERVEEAKLLVTQGASI 198 Score = 44.7 bits (104), Expect = 2e-04 Identities = 26/86 (30%), Positives = 40/86 (46%), Gaps = 1/86 (1%) Frame = +3 Query: 309 AWAGHVDVVK-CLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKG 485 A+ G +D +K + K +H+A GH E+V LL G V K+ G Sbjct: 14 AYNGKLDELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNEKDDAG 73 Query: 486 FTALHFAAQNSHLELVKYLVRRGVDI 563 ++ LH AA E+VK L+ +G + Sbjct: 74 WSPLHIAASAGRDEIVKALLIKGAQV 99 Score = 34.3 bits (77), Expect = 0.26 Identities = 19/80 (23%), Positives = 37/80 (46%) Frame = +3 Query: 267 NSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELL 446 ++++ T +H AA G++ +V L +K +H A + +E + L+ Sbjct: 133 DAKNHYDATAMHRAAAKGNLKMVHILLFYKASTNIQDTEGNTPLHLACDEERVEEAKLLV 192 Query: 447 ASGASVKAKNRKGFTALHFA 506 GAS+ +N++ T L A Sbjct: 193 TQGASIYIENKEEKTPLQVA 212
>DAPK1_HUMAN (P53355) Death-associated protein kinase 1 (EC 2.7.11.1) (DAP| kinase 1) Length = 1432 Score = 61.2 bits (147), Expect = 2e-09 Identities = 34/113 (30%), Positives = 61/113 (53%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AA G + ++LC++ +N ++R TPL A+ G+ D+V+CL +H Sbjct: 484 LHCAAWHGYYSVAKALCEAG-CNVNIKNREGETPLLTASARGYHDIVECLAEHGADLNAC 542 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELV 533 +H A ++ +EV++ LL+ G V ++R G T LH A ++ ++ +V Sbjct: 543 DKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIV 595 Score = 55.1 bits (131), Expect = 1e-07 Identities = 37/120 (30%), Positives = 54/120 (45%) Frame = +3 Query: 189 LKLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXX 368 + LH A R +++L S ++ +DR TPLH+A G++ +V LC+ Sbjct: 548 IALHLAVRRCQMEVIKTLL-SQGCFVDYQDRHGNTPLHVACKDGNMPIVVALCEANCNLD 606 Query: 369 XXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVR 548 +H A+ G L+VVR L GASV+A G TA A H + L R Sbjct: 607 ISNKYGRTPLHLAANNGILDVVRYLCLMGASVEALTTDGKTAEDLARSEQHEHVAGLLAR 666 Score = 54.3 bits (129), Expect = 2e-07 Identities = 36/122 (29%), Positives = 58/122 (47%), Gaps = 2/122 (1%) Frame = +3 Query: 204 AARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDV--VKCLCKHKXXXXXXX 377 AAR G ++ L ++ L+ +D+ LH+AA GH DV V+ LC Sbjct: 419 AARHGHVDTLKFLSENK-CPLDVKDKSGEMALHVAARYGHADVAQVQVLCSFGSNPNIQD 477 Query: 378 XXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGV 557 +H A+ G+ V + L +G +V KNR+G T L A+ + ++V+ L G Sbjct: 478 KEEETPLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIVECLAEHGA 537 Query: 558 DI 563 D+ Sbjct: 538 DL 539 Score = 43.1 bits (100), Expect = 5e-04 Identities = 21/94 (22%), Positives = 47/94 (50%) Frame = +3 Query: 264 LNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVREL 443 +N ++ PL +AA G++ +++ L K +++A++ GH++ ++ L Sbjct: 372 VNQPNKHGTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAARHGHVDTLKFL 431 Query: 444 LASGASVKAKNRKGFTALHFAAQNSHLELVKYLV 545 + + K++ G ALH AA+ H ++ + V Sbjct: 432 SENKCPLDVKDKSGEMALHVAARYGHADVAQVQV 465
>ASB2_BOVIN (Q3SX45) Ankyrin repeat and SOCS box protein 2 (ASB-2)| Length = 633 Score = 61.2 bits (147), Expect = 2e-09 Identities = 44/160 (27%), Positives = 67/160 (41%), Gaps = 33/160 (20%) Frame = +3 Query: 189 LKLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVD------------- 329 L LH+AA G +++L + P ++ R T L+LA GHVD Sbjct: 138 LPLHEAAYYGQLNCLKALHRAYPAVIDQRTLQEETALYLATCRGHVDCLQFLLQAGAEPD 197 Query: 330 --------------------VVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLA 449 V+ L ++K +H + + LEV+ L++ Sbjct: 198 ISNKSRETPLYKACERKNVEAVRILVQYKADTNHRCNRGWTALHESVARNDLEVMEILVS 257 Query: 450 SGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDITT 569 GA V+AKN G T L AAQ+ LE +++L + G DI T Sbjct: 258 GGAKVEAKNAYGITPLFVAAQSGQLEALRFLAKYGADINT 297 Score = 54.7 bits (130), Expect = 2e-07 Identities = 31/117 (26%), Positives = 56/117 (47%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH++ D +E L S + +++ TPL +AA +G ++ ++ L K+ Sbjct: 240 LHESVARNDLEVMEILV-SGGAKVEAKNAYGITPLFVAAQSGQLEALRFLAKYGADINTQ 298 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLV 545 ++ A + GH EVV LL+ GA N+ G LH A++ + +V+ L+ Sbjct: 299 ASDSASALYEACKNGHEEVVEFLLSQGADANKTNKDGMLPLHIASKKGNYRIVQMLL 355 Score = 43.5 bits (101), Expect = 4e-04 Identities = 32/122 (26%), Positives = 52/122 (42%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 L+KA + AV L N R T LH + ++V++ L Sbjct: 207 LYKACERKNVEAVRILVQYKA-DTNHRCNRGWTALHESVARNDLEVMEILVSGGAKVEAK 265 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 + A+Q G LE +R L GA + + +AL+ A +N H E+V++L+ +G Sbjct: 266 NAYGITPLFVAAQSGQLEALRFLAKYGADINTQASDSASALYEACKNGHEEVVEFLLSQG 325 Query: 555 VD 560 D Sbjct: 326 AD 327
>TNI3K_RAT (Q7TQP6) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 834 Score = 61.2 bits (147), Expect = 2e-09 Identities = 39/125 (31%), Positives = 60/125 (48%), Gaps = 2/125 (1%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AA +G A E L +N +D + TPLH+AA+ GH V L K Sbjct: 137 LHIAAIAGHPEAAEVLLQHGA-NVNVQDAVFFTPLHIAAYYGHEQVTSVLLKFGADVNVS 195 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASG--ASVKAKNRKGFTALHFAAQNSHLELVKYLVR 548 +H AS KG +V+ L+ G A V A++ + LHF ++ H +V YL++ Sbjct: 196 GEVGDRPLHLASAKGFFNIVKLLVEEGSKADVNAQDNEDHVPLHFCSRFGHHNIVSYLLQ 255 Query: 549 RGVDI 563 +++ Sbjct: 256 SDLEV 260 Score = 52.0 bits (123), Expect = 1e-06 Identities = 29/88 (32%), Positives = 38/88 (43%) Frame = +3 Query: 291 TPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKA 470 T LH+AA AGH + + L +H +H A+ GH +V LL GA V Sbjct: 135 TALHIAAIAGHPEAAEVLLQHGANVNVQDAVFFTPLHIAAYYGHEQVTSVLLKFGADVNV 194 Query: 471 KNRKGFTALHFAAQNSHLELVKYLVRRG 554 G LH A+ +VK LV G Sbjct: 195 SGEVGDRPLHLASAKGFFNIVKLLVEEG 222 Score = 45.4 bits (106), Expect = 1e-04 Identities = 38/131 (29%), Positives = 59/131 (45%), Gaps = 8/131 (6%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSD----PLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXX 362 LH +R G V L SD P +N TPLHLA + G+ +V K + + Sbjct: 238 LHFCSRFGHHNIVSYLLQSDLEVQPHVINI---YGDTPLHLACYNGNFEVAKEIVQVTGT 294 Query: 363 XXXXXXX--XXXXIHFASQKG-HLEVVRELLASGA-SVKAKNRKGFTALHFAAQNSHLEL 530 H A G ++++V+ LL A ++ + R G T LH A + H+ L Sbjct: 295 ESLTKENIFSETAFHSACTYGKNIDLVKFLLDQNAVNINHRGRDGHTGLHSACYHGHIRL 354 Query: 531 VKYLVRRGVDI 563 V++L+ G D+ Sbjct: 355 VQFLLDNGADM 365 Score = 45.1 bits (105), Expect = 1e-04 Identities = 25/89 (28%), Positives = 39/89 (43%) Frame = +3 Query: 297 LHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKN 476 LHLA + +++ L +H A+ GH E LL GA+V ++ Sbjct: 104 LHLAVYKDSPELITSLLHSGADVQQVGYGGLTALHIAAIAGHPEAAEVLLQHGANVNVQD 163 Query: 477 RKGFTALHFAAQNSHLELVKYLVRRGVDI 563 FT LH AA H ++ L++ G D+ Sbjct: 164 AVFFTPLHIAAYYGHEQVTSVLLKFGADV 192 Score = 32.3 bits (72), Expect = 0.97 Identities = 16/49 (32%), Positives = 22/49 (44%) Frame = +3 Query: 417 GHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 G+ +R L+ G R GF ALH A EL+ L+ G D+ Sbjct: 78 GNKSHIRALMLKGLRPSRLTRNGFPALHLAVYKDSPELITSLLHSGADV 126
>TNI3K_MOUSE (Q5GIG6) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 833 Score = 60.8 bits (146), Expect = 3e-09 Identities = 39/124 (31%), Positives = 61/124 (49%), Gaps = 1/124 (0%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AA +G AVE L +N +D + TPLH+AA+ GH V L K Sbjct: 137 LHIAAIAGHPEAVEVLLQHGA-NVNVQDAVFFTPLHIAAYYGHEQVTSVLLKFGADVNVS 195 Query: 375 XXXXXXXIHFASQKGHLEVVRELL-ASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRR 551 +H AS KG +V+ L+ + A V A++ + LHF ++ H +V YL++ Sbjct: 196 GEVGDRPLHLASAKGFFNIVKLLVEGNKADVNAQDNEDHVPLHFCSRFGHHNIVSYLLQS 255 Query: 552 GVDI 563 +++ Sbjct: 256 DLEV 259 Score = 51.2 bits (121), Expect = 2e-06 Identities = 29/85 (34%), Positives = 38/85 (44%) Frame = +3 Query: 291 TPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKA 470 T LH+AA AGH + V+ L +H +H A+ GH +V LL GA V Sbjct: 135 TALHIAAIAGHPEAVEVLLQHGANVNVQDAVFFTPLHIAAYYGHEQVTSVLLKFGADVNV 194 Query: 471 KNRKGFTALHFAAQNSHLELVKYLV 545 G LH A+ +VK LV Sbjct: 195 SGEVGDRPLHLASAKGFFNIVKLLV 219 Score = 48.1 bits (113), Expect = 2e-05 Identities = 26/89 (29%), Positives = 41/89 (46%) Frame = +3 Query: 297 LHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKN 476 LHLA + ++++ L +H A+ GH E V LL GA+V ++ Sbjct: 104 LHLAVYKDSLELITSLLHSGADVQQAGYGGLTALHIAAIAGHPEAVEVLLQHGANVNVQD 163 Query: 477 RKGFTALHFAAQNSHLELVKYLVRRGVDI 563 FT LH AA H ++ L++ G D+ Sbjct: 164 AVFFTPLHIAAYYGHEQVTSVLLKFGADV 192 Score = 44.7 bits (104), Expect = 2e-04 Identities = 38/131 (29%), Positives = 58/131 (44%), Gaps = 8/131 (6%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSD----PLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXX 362 LH +R G V L SD P +N TPLHLA + G+ +V K + Sbjct: 237 LHFCSRFGHHNIVSYLLQSDLEVQPHVINI---YGDTPLHLACYNGNFEVAKEIVHVTGT 293 Query: 363 XXXXXXX--XXXXIHFASQKG-HLEVVRELLASGA-SVKAKNRKGFTALHFAAQNSHLEL 530 H A G ++++V+ LL A ++ + R G T LH A + H+ L Sbjct: 294 ESLTKENIFSETAFHSACTYGKNIDLVKFLLDQNAVNINHRGRDGHTGLHSACYHGHIRL 353 Query: 531 VKYLVRRGVDI 563 V++L+ G D+ Sbjct: 354 VQFLLDNGADM 364 Score = 35.0 bits (79), Expect = 0.15 Identities = 17/49 (34%), Positives = 23/49 (46%) Frame = +3 Query: 417 GHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 G+ +R L+ G R GF ALH A LEL+ L+ G D+ Sbjct: 78 GNKSHIRALMLKGLRPSRLTRNGFPALHLAVYKDSLELITSLLHSGADV 126
>MIB_DROME (Q9VUX2) Ubiquitin ligase protein mind-bomb (EC 6.3.2.-) (Mind bomb| homolog) (D-mib) Length = 1226 Score = 60.8 bits (146), Expect = 3e-09 Identities = 40/122 (32%), Positives = 59/122 (48%) Frame = +3 Query: 186 DLKLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXX 365 D +H AA +AA +E L + LN+R++ +T LH+A GH++VVK L Sbjct: 602 DRAVHHAAFGDEAAVIEILAKAGA-DLNARNKRRQTSLHIAVNKGHLNVVKTLLTLGCHP 660 Query: 366 XXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLV 545 +H A K H E++ LL GA + N GF ALH AA + +K L+ Sbjct: 661 SLQDSEGDTPLHDAISKEHDEMLSLLLDFGADITLNNNNGFNALHHAALKGNPSAMKILL 720 Query: 546 RR 551 + Sbjct: 721 TK 722 Score = 51.6 bits (122), Expect = 2e-06 Identities = 34/124 (27%), Positives = 54/124 (43%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 L A+++G ++ L + + D+ +H AA+ V++ L K Sbjct: 572 LQAASQNGHIEVIQVLL-RHAVDVEIEDKDGDRAVHHAAFGDEAAVIEILAKAGADLNAR 630 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 +H A KGHL VV+ LL G ++ +G T LH A H E++ L+ G Sbjct: 631 NKRRQTSLHIAVNKGHLNVVKTLLTLGCHPSLQDSEGDTPLHDAISKEHDEMLSLLLDFG 690 Query: 555 VDIT 566 DIT Sbjct: 691 ADIT 694 Score = 50.8 bits (120), Expect = 3e-06 Identities = 26/88 (29%), Positives = 43/88 (48%) Frame = +3 Query: 291 TPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKA 470 T L A+ GH++V++ L +H +H A+ V+ L +GA + A Sbjct: 570 TALQAASQNGHIEVIQVLLRHAVDVEIEDKDGDRAVHHAAFGDEAAVIEILAKAGADLNA 629 Query: 471 KNRKGFTALHFAAQNSHLELVKYLVRRG 554 +N++ T+LH A HL +VK L+ G Sbjct: 630 RNKRRQTSLHIAVNKGHLNVVKTLLTLG 657 Score = 41.2 bits (95), Expect = 0.002 Identities = 35/131 (26%), Positives = 56/131 (42%), Gaps = 5/131 (3%) Frame = +3 Query: 186 DLKLHKAARSGDAAAVESLCD-SDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLC---KH 353 D LH A + L D + LN+ + + LH AA G+ +K L Sbjct: 668 DTPLHDAISKEHDEMLSLLLDFGADITLNNNNGFNA--LHHAALKGNPSAMKILLTKTNR 725 Query: 354 KXXXXXXXXXXXXXIHFASQKGHLEVVRELLASG-ASVKAKNRKGFTALHFAAQNSHLEL 530 +H A+ H+E+ L+ G A++ +N TALH A + H+++ Sbjct: 726 PWIVEEKKDDGYTALHLAALNNHVEIAELLVHMGKANMDRQNVNLQTALHLAVERQHVQI 785 Query: 531 VKYLVRRGVDI 563 VK LV+ G D+ Sbjct: 786 VKLLVQDGADL 796 Score = 33.1 bits (74), Expect = 0.57 Identities = 13/27 (48%), Positives = 20/27 (74%) Frame = +3 Query: 483 GFTALHFAAQNSHLELVKYLVRRGVDI 563 G TAL A+QN H+E+++ L+R VD+ Sbjct: 568 GHTALQAASQNGHIEVIQVLLRHAVDV 594
>ANKK1_HUMAN (Q8NFD2) Ankyrin repeat and protein kinase domain-containing| protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (X-kinase) (SgK288) Length = 765 Score = 60.8 bits (146), Expect = 3e-09 Identities = 39/116 (33%), Positives = 57/116 (49%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AA G + V+ L S L+++ R RTPLHLA G V ++ L K Sbjct: 498 LHVAAYFGHVSLVK-LLTSQGAELDAQQRNLRTPLHLAVERGKVRAIQHLLKSGAVPDAL 556 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYL 542 +H A+ +G + + LL GAS++ +G+T LH AA HLE++ L Sbjct: 557 DQSGYGPLHTAAARGKYLICKMLLRYGASLELPTHQGWTPLHLAAYKGHLEIIHLL 612 Score = 58.9 bits (141), Expect = 1e-08 Identities = 38/125 (30%), Positives = 58/125 (46%), Gaps = 2/125 (1%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCD--SDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXX 368 LH AA++ L +DP N + +TPLH+AA+ GHV +VK L Sbjct: 465 LHLAAQNNFENVARLLVSRQADP---NLHEAEGKTPLHVAAYFGHVSLVKLLTSQGAELD 521 Query: 369 XXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVR 548 +H A ++G + ++ LL SGA A ++ G+ LH AA + K L+R Sbjct: 522 AQQRNLRTPLHLAVERGKVRAIQHLLKSGAVPDALDQSGYGPLHTAAARGKYLICKMLLR 581 Query: 549 RGVDI 563 G + Sbjct: 582 YGASL 586 Score = 57.8 bits (138), Expect = 2e-08 Identities = 34/120 (28%), Positives = 59/120 (49%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AA++GD L D +++++R TPLHLAA +V + L + Sbjct: 432 LHFAAQNGDDGTARLLLDHGA-CVDAQEREGWTPLHLAAQNNFENVARLLVSRQADPNLH 490 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 +H A+ GH+ +V+ L + GA + A+ R T LH A + + +++L++ G Sbjct: 491 EAEGKTPLHVAAYFGHVSLVKLLTSQGAELDAQQRNLRTPLHLAVERGKVRAIQHLLKSG 550 Score = 55.5 bits (132), Expect = 1e-07 Identities = 36/122 (29%), Positives = 57/122 (46%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH A G A++ L S + ++ D+ PLH AA G + K L ++ Sbjct: 531 LHLAVERGKVRAIQHLLKSGAVP-DALDQSGYGPLHTAAARGKYLICKMLLRYGASLELP 589 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 +H A+ KGHLE++ L S A++ A +T LH AA++ +V L++ G Sbjct: 590 THQGWTPLHLAAYKGHLEIIHLLAESHANMGALGAVNWTPLHLAARHGEEAVVSALLQCG 649 Query: 555 VD 560 D Sbjct: 650 AD 651 Score = 53.5 bits (127), Expect = 4e-07 Identities = 27/76 (35%), Positives = 38/76 (50%) Frame = +3 Query: 291 TPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKA 470 TPLHLAA+ GH++++ L + +H A++ G VV LL GA A Sbjct: 595 TPLHLAAYKGHLEIIHLLAESHANMGALGAVNWTPLHLAARHGEEAVVSALLQCGADPNA 654 Query: 471 KNRKGFTALHFAAQNS 518 + G+T LH A Q S Sbjct: 655 AEQSGWTPLHLAVQRS 670 Score = 53.5 bits (127), Expect = 4e-07 Identities = 33/90 (36%), Positives = 43/90 (47%) Frame = +3 Query: 291 TPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKA 470 TPL +AA D+ L H +HFA+Q G R LL GA V A Sbjct: 397 TPLLIAAQDQQPDLCALLLAHGADANRVDEDGWAPLHFAAQNGDDGTARLLLDHGACVDA 456 Query: 471 KNRKGFTALHFAAQNSHLELVKYLVRRGVD 560 + R+G+T LH AAQN+ + + LV R D Sbjct: 457 QEREGWTPLHLAAQNNFENVARLLVSRQAD 486 Score = 51.6 bits (122), Expect = 2e-06 Identities = 37/123 (30%), Positives = 54/123 (43%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AA G + L +S + + ++ TPLHLAA G VV L + Sbjct: 597 LHLAAYKGHLEIIHLLAESHA-NMGALGAVNWTPLHLAARHGEEAVVSALLQCGADPNAA 655 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 +H A Q+ V LL A+V A+N+ G+T H AA + ++K LV G Sbjct: 656 EQSGWTPLHLAVQRSTFLSVINLLEHHANVHARNKVGWTPAHLAALKGNTAILKVLVEAG 715 Query: 555 VDI 563 + Sbjct: 716 AQL 718 Score = 47.8 bits (112), Expect = 2e-05 Identities = 34/127 (26%), Positives = 58/127 (45%), Gaps = 2/127 (1%) Frame = +3 Query: 195 LHKAARSGDAAAVESL--CDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXX 368 LH AAR G+ A V +L C +DP N+ ++ TPLHLA V L +H Sbjct: 630 LHLAARHGEEAVVSALLQCGADP---NAAEQSGWTPLHLAVQRSTFLSVINLLEHHANVH 686 Query: 369 XXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVR 548 H A+ KG+ +++ L+ +GA + ++ T L A ++ ++ +L Sbjct: 687 ARNKVGWTPAHLAALKGNTAILKVLVEAGAQLDVQDGVSCTPLQLALRSRKQGIMSFLEG 746 Query: 549 RGVDITT 569 + + T Sbjct: 747 KEPSVAT 753 Score = 44.3 bits (103), Expect = 2e-04 Identities = 29/99 (29%), Positives = 39/99 (39%) Frame = +3 Query: 267 NSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELL 446 N D PLH AA G + L H +H A+Q V R L+ Sbjct: 422 NRVDEDGWAPLHFAAQNGDDGTARLLLDHGACVDAQEREGWTPLHLAAQNNFENVARLLV 481 Query: 447 ASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 + A +G T LH AA H+ LVK L +G ++ Sbjct: 482 SRQADPNLHEAEGKTPLHVAAYFGHVSLVKLLTSQGAEL 520 Score = 42.0 bits (97), Expect = 0.001 Identities = 26/88 (29%), Positives = 37/88 (42%) Frame = +3 Query: 291 TPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKA 470 TPLH G V+ V+ L H+ + A+Q ++ LLA GA Sbjct: 364 TPLHFLVAQGSVEQVRLLLAHEVDVDCQTASGYTPLLIAAQDQQPDLCALLLAHGADANR 423 Query: 471 KNRKGFTALHFAAQNSHLELVKYLVRRG 554 + G+ LHFAAQN + L+ G Sbjct: 424 VDEDGWAPLHFAAQNGDDGTARLLLDHG 451 Score = 37.0 bits (84), Expect = 0.039 Identities = 20/55 (36%), Positives = 28/55 (50%) Frame = +3 Query: 396 IHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVD 560 +HF +G +E VR LLA V + G+T L AAQ+ +L L+ G D Sbjct: 366 LHFLVAQGSVEQVRLLLAHEVDVDCQTASGYTPLLIAAQDQQPDLCALLLAHGAD 420
>INVS_BRARE (Q8UVC1) Inversin| Length = 1021 Score = 60.5 bits (145), Expect = 3e-09 Identities = 36/122 (29%), Positives = 62/122 (50%), Gaps = 2/122 (1%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AA G+A E L ++ ++ N +D+ RTPL AA+AG+++ + L +H Sbjct: 420 LHWAALGGNAEVCEVLMENG-ISPNLQDQAGRTPLQCAAYAGYINCMALLIQHDADPNIQ 478 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGA--SVKAKNRKGFTALHFAAQNSHLELVKYLVR 548 +H++ G+L+ V+ LL GA + + +T L +A H EL ++L+ Sbjct: 479 DKEGRTALHWSCNNGYLDAVKLLLGCGAFPNHMEHTEERYTPLDYALLGEHQELTQFLLE 538 Query: 549 RG 554 G Sbjct: 539 HG 540 Score = 51.6 bits (122), Expect = 2e-06 Identities = 32/119 (26%), Positives = 57/119 (47%) Frame = +3 Query: 192 KLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXX 371 ++H AA +GD + L L +S D+ RTPL A +D + L K Sbjct: 11 QVHAAAVNGDKNTLHKLITESALR-DSEDQFGRTPLMYCVLADRLDCAEVLLKAGAGINK 69 Query: 372 XXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVR 548 +H A+QKG++ ++ LL+ A + K+ + T LH A+++S + + L++ Sbjct: 70 TDHSQRTALHLAAQKGNVRFMKLLLSRHADWRLKDLEEMTPLHLASRHSSSKPLSLLLK 128 Score = 50.8 bits (120), Expect = 3e-06 Identities = 34/122 (27%), Positives = 55/122 (45%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AA SG + V L + + ++ D + TPL A GH DV+ L K Sbjct: 354 LHAAALSGHVSTVRLLLEQGGM-VDPLDVMKHTPLFRACEMGHRDVILTLIKGGARVDLV 412 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 +H+A+ G+ EV L+ +G S +++ G T L AA ++ + L++ Sbjct: 413 DIDGHSALHWAALGGNAEVCEVLMENGISPNLQDQAGRTPLQCAAYAGYINCMALLIQHD 472 Query: 555 VD 560 D Sbjct: 473 AD 474 Score = 50.4 bits (119), Expect = 3e-06 Identities = 34/126 (26%), Positives = 58/126 (46%), Gaps = 3/126 (2%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLC-KHKXXXXX 371 LH A G+ A VE L + ++ + D L RTPLH AA GH +V L ++K Sbjct: 218 LHFAVADGNEAVVEVLTSYEGCSVTAYDNLFRTPLHWAALLGHAKIVHLLLERNKSGMIP 277 Query: 372 XXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYL--V 545 +H+ +Q + V L + + +G TA +AA +++K + + Sbjct: 278 SDSQGATPLHYGAQSNFADTVAVFLKHHSVRDEPDLEGRTAFMWAAGKGSNDVIKIMLDL 337 Query: 546 RRGVDI 563 ++ +DI Sbjct: 338 KKDIDI 343 Score = 42.7 bits (99), Expect = 7e-04 Identities = 33/112 (29%), Positives = 53/112 (47%), Gaps = 2/112 (1%) Frame = +3 Query: 219 DAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKX-XXXXXXXXXXXX 395 +AA ESL LN +D RTPLH A G+ VV+ L ++ Sbjct: 199 EAAPTESL-------LNWQDYEGRTPLHFAVADGNEAVVEVLTSYEGCSVTAYDNLFRTP 251 Query: 396 IHFASQKGHLEVVRELLASGAS-VKAKNRKGFTALHFAAQNSHLELVKYLVR 548 +H+A+ GH ++V LL S + + +G T LH+ AQ++ + V ++ Sbjct: 252 LHWAALLGHAKIVHLLLERNKSGMIPSDSQGATPLHYGAQSNFADTVAVFLK 303 Score = 40.4 bits (93), Expect = 0.004 Identities = 31/123 (25%), Positives = 55/123 (44%), Gaps = 7/123 (5%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDS-DPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXX 371 LH A+R + + L P ++++DR +T LH +A+ H + VK L KH Sbjct: 111 LHLASRHSSSKPLSLLLKHMAPGEVDTQDRNKQTALHWSAFYNHPEHVKLLIKHDSNIGI 170 Query: 372 XXXXXXXXIHFASQKGHLEVVR------ELLASGASVKAKNRKGFTALHFAAQNSHLELV 533 +H+A+ H R E + + + ++ +G T LHFA + + +V Sbjct: 171 PDSEGKIPLHWAAHNKHPNATRTVRCILEAAPTESLLNWQDYEGRTPLHFAVADGNEAVV 230 Query: 534 KYL 542 + L Sbjct: 231 EVL 233
>PSD10_HUMAN (O75832) 26S proteasome non-ATPase regulatory subunit 10 (26S| proteasome regulatory subunit p28) (Gankyrin) Length = 226 Score = 60.5 bits (145), Expect = 3e-09 Identities = 38/125 (30%), Positives = 58/125 (46%) Frame = +3 Query: 186 DLKLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXX 365 +L + A SG ++ +D D+ SRT LH A AGH ++V+ L + Sbjct: 7 NLMVCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPV 66 Query: 366 XXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLV 545 +H A+ G E+V+ LL GA V A N+ G T LH+AA + E+ L+ Sbjct: 67 NDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLL 126 Query: 546 RRGVD 560 G + Sbjct: 127 EGGAN 131 Score = 55.8 bits (133), Expect = 8e-08 Identities = 36/117 (30%), Positives = 56/117 (47%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH A +G VE L + +N +D +PLH+AA AG ++VK L Sbjct: 44 LHWACSAGHTEIVEFLLQLG-VPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAV 102 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLV 545 +H+A+ K E+ LL GA+ AK+ TA+H AA +L+++ L+ Sbjct: 103 NQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILL 159 Score = 48.9 bits (115), Expect = 1e-05 Identities = 35/123 (28%), Positives = 56/123 (45%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AA +G V++L +N+ ++ TPLH AA ++ L + Sbjct: 77 LHIAASAGRDEIVKALLGKGA-QVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAK 135 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 +H A+ KG+L+++ LL AS ++ +G T LH A +E K LV +G Sbjct: 136 DHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQG 195 Query: 555 VDI 563 I Sbjct: 196 ASI 198 Score = 44.3 bits (103), Expect = 2e-04 Identities = 25/86 (29%), Positives = 41/86 (47%), Gaps = 1/86 (1%) Frame = +3 Query: 309 AWAGHVDVVK-CLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKG 485 A++G ++ +K + K +H+A GH E+V LL G V K+ G Sbjct: 14 AYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAG 73 Query: 486 FTALHFAAQNSHLELVKYLVRRGVDI 563 ++ LH AA E+VK L+ +G + Sbjct: 74 WSPLHIAASAGRDEIVKALLGKGAQV 99 Score = 36.6 bits (83), Expect = 0.051 Identities = 19/80 (23%), Positives = 38/80 (47%) Frame = +3 Query: 267 NSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELL 446 +++D T +H AA G++ ++ L +K +H A + +E + L+ Sbjct: 133 DAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLV 192 Query: 447 ASGASVKAKNRKGFTALHFA 506 + GAS+ +N++ T L A Sbjct: 193 SQGASIYIENKEEKTPLQVA 212
>EHMT2_MOUSE (Q9Z148) Histone-lysine N-methyltransferase, H3 lysine-9 specific 3| (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a) Length = 1263 Score = 60.1 bits (144), Expect = 4e-09 Identities = 36/125 (28%), Positives = 67/125 (53%), Gaps = 1/125 (0%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AA+ G L + +N+ D+ RTPL A H++V + + + Sbjct: 742 LHAAAQKGSVEICHVLLQAGA-NINAVDKQQRTPLMEAVVNNHLEVARYMVQLGGCVYSK 800 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASG-ASVKAKNRKGFTALHFAAQNSHLELVKYLVRR 551 +H A++ G+LE+V LL++G V A++ G+T + +AA++ H+++++ L+ R Sbjct: 801 EEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIDVIRMLLTR 860 Query: 552 GVDIT 566 G D+T Sbjct: 861 GADVT 865 Score = 55.1 bits (131), Expect = 1e-07 Identities = 35/122 (28%), Positives = 56/122 (45%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AA+ G+ V L + + +N++D TP+ AA H+DV++ L Sbjct: 808 LHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIDVIRMLLTRGADVTLT 867 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 +H+AS G + LL + + A N G T LH AA+ S+ + V + RG Sbjct: 868 DNEENICLHWASFTGSAAIAEVLLNAQCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRG 927 Query: 555 VD 560 + Sbjct: 928 AN 929 Score = 50.4 bits (119), Expect = 3e-06 Identities = 38/126 (30%), Positives = 57/126 (45%), Gaps = 2/126 (1%) Frame = +3 Query: 192 KLHKAARSGDAAAVE-SLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXX 368 +L+ + + G+ V L D+ S + RTPLH AA G V++ L + Sbjct: 706 QLYLSVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANIN 765 Query: 369 XXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVR 548 + A HLEV R ++ G V +K G T LH AA+ +LE+V L+ Sbjct: 766 AVDKQQRTPLMEAVVNNHLEVARYMVQLGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLS 825 Query: 549 RG-VDI 563 G VD+ Sbjct: 826 TGQVDV 831 Score = 33.5 bits (75), Expect = 0.44 Identities = 24/99 (24%), Positives = 45/99 (45%), Gaps = 1/99 (1%) Frame = +3 Query: 270 SRDRLSRTPLHLAAWAGHVDVVKCLCKH-KXXXXXXXXXXXXXIHFASQKGHLEVVRELL 446 S++ T LH AA G++++V L + I +A++ H++V+R LL Sbjct: 799 SKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIDVIRMLL 858 Query: 447 ASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 GA V + + LH+A+ + + L+ D+ Sbjct: 859 TRGADVTLTDNEENICLHWASFTGSAAIAEVLLNAQCDL 897
>BARD1_HUMAN (Q99728) BRCA1-associated RING domain protein 1 (BARD-1)| Length = 777 Score = 60.1 bits (144), Expect = 4e-09 Identities = 40/115 (34%), Positives = 57/115 (49%), Gaps = 2/115 (1%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCD--SDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXX 368 LH A+ GD +VE L SDP N +D TPLH A GH+ VV+ L +HK Sbjct: 432 LHIASIKGDIPSVEYLLQNGSDP---NVKDHAGWTPLHEACNHGHLKVVELLLQHKALVN 488 Query: 369 XXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELV 533 +H A++ GH+++V+ LL+ GAS A N G + + S L+ Sbjct: 489 TTGYQNDSPLHDAAKNGHVDIVKLLLSYGASRNAVNIFGLRPVDYTDDESMKSLL 543 Score = 47.0 bits (110), Expect = 4e-05 Identities = 29/94 (30%), Positives = 45/94 (47%) Frame = +3 Query: 273 RDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLAS 452 R+ T LH+A+ G + V+ L ++ +H A GHL+VV LL Sbjct: 424 RNHRGETLLHIASIKGDIPSVEYLLQNGSDPNVKDHAGWTPLHEACNHGHLKVVELLLQH 483 Query: 453 GASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 A V + + LH AA+N H+++VK L+ G Sbjct: 484 KALVNTTGYQNDSPLHDAAKNGHVDIVKLLLSYG 517 Score = 41.2 bits (95), Expect = 0.002 Identities = 20/58 (34%), Positives = 33/58 (56%) Frame = +3 Query: 396 IHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDITT 569 +H AS KG + V LL +G+ K+ G+T LH A + HL++V+ L++ + T Sbjct: 432 LHIASIKGDIPSVEYLLQNGSDPNVKDHAGWTPLHEACNHGHLKVVELLLQHKALVNT 489
>AKR1_CRYNE (Q5KP49) Palmitoyltransferase AKR1 (EC 2.3.1.-) (Ankyrin| repeat-containing protein AKR1) Length = 776 Score = 60.1 bits (144), Expect = 4e-09 Identities = 38/128 (29%), Positives = 62/128 (48%), Gaps = 2/128 (1%) Frame = +3 Query: 186 DLKLHKAARSGDAAAVESLCDSDP-LALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXX 362 DL +H A+ GD AA+ ++ +P L L++RD TPLH AA H+ + L Sbjct: 70 DLDIHALAQRGDTAAIAAMLQENPSLNLSARDAQDVTPLHWAAINAHMGTCRLLIDSGAD 129 Query: 363 XXXXXXXXXXX-IHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKY 539 + +A++ GHL VV L++ GA + +GF LH +S + + Y Sbjct: 130 IDAIGGELKATPLQWAARNGHLYVVHLLISRGADPNIHDSQGFNTLHLITHSSAVMPLLY 189 Query: 540 LVRRGVDI 563 ++ + V I Sbjct: 190 MLHQPVAI 197 Score = 40.4 bits (93), Expect = 0.004 Identities = 24/86 (27%), Positives = 39/86 (45%) Frame = +3 Query: 255 PLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVV 434 P+A++ +D T L AA+ G V L +H +H+A+ KG+ + Sbjct: 194 PVAIDEKDTDGHTALMWAAYQGDALSVDLLIRHGASVNSTDNAGMTPLHWAAVKGNKVSI 253 Query: 435 RELLASGASVKAKNRKGFTALHFAAQ 512 L+ +GAS+ AK G T A + Sbjct: 254 MHLVEAGASLDAKEEAGKTPRDMAEE 279 Score = 35.0 bits (79), Expect = 0.15 Identities = 32/125 (25%), Positives = 49/125 (39%), Gaps = 2/125 (1%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCD--SDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXX 368 L AAR+G V L +DP N D LHL + V + + Sbjct: 142 LQWAARNGHLYVVHLLISRGADP---NIHDSQGFNTLHLITHSSAVMPLLYMLHQPVAID 198 Query: 369 XXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVR 548 + +A+ +G V L+ GASV + + G T LH+AA + + +LV Sbjct: 199 EKDTDGHTALMWAAYQGDALSVDLLIRHGASVNSTDNAGMTPLHWAAVKGNKVSIMHLVE 258 Query: 549 RGVDI 563 G + Sbjct: 259 AGASL 263
>YL483_MIMIV (Q5UQF1) Putative ankyrin repeat protein L483| Length = 408 Score = 59.7 bits (143), Expect = 6e-09 Identities = 35/91 (38%), Positives = 54/91 (59%) Frame = +3 Query: 297 LHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKN 476 + LA+ GH++VVK L + I ++S GHLEVV+ L++ GA ++++N Sbjct: 263 VRLASSNGHLEVVKYLVSLRANIRARCDFA---IKWSSSNGHLEVVKYLVSQGADIRSQN 319 Query: 477 RKGFTALHFAAQNSHLELVKYLVRRGVDITT 569 A+ +A+ N HLE+VKYLV +G DI T Sbjct: 320 DY---AVRYASTNGHLEVVKYLVGQGADIRT 347 Score = 52.8 bits (125), Expect = 7e-07 Identities = 26/56 (46%), Positives = 40/56 (71%) Frame = +3 Query: 396 IHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 + ASQ GHLEV+ L+A GA+++A N A+ +A++N +L++VKYLV +G DI Sbjct: 113 VQLASQNGHLEVIEYLVAQGANIRADND---YAVIWASRNGYLDIVKYLVSQGADI 165 Score = 51.2 bits (121), Expect = 2e-06 Identities = 29/87 (33%), Positives = 51/87 (58%), Gaps = 3/87 (3%) Frame = +3 Query: 312 WA---GHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRK 482 WA G++D+VK L + +AS+ GHL+VV+ L++ GA+++ +N Sbjct: 145 WASRNGYLDIVKYLVSQ---GADIRANNDYAVRWASRNGHLKVVKYLVSLGANIRTENDY 201 Query: 483 GFTALHFAAQNSHLELVKYLVRRGVDI 563 A+ +A++N +L +V+YLV +G DI Sbjct: 202 ---AIKYASENGYLRIVEYLVSQGADI 225 Score = 51.2 bits (121), Expect = 2e-06 Identities = 29/91 (31%), Positives = 53/91 (58%) Frame = +3 Query: 297 LHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKN 476 + LA+ GH++V++ L + +AS+ G+L++V+ L++ GA ++A N Sbjct: 113 VQLASQNGHLEVIEYLVAQ---GANIRADNDYAVIWASRNGYLDIVKYLVSQGADIRANN 169 Query: 477 RKGFTALHFAAQNSHLELVKYLVRRGVDITT 569 A+ +A++N HL++VKYLV G +I T Sbjct: 170 DY---AVRWASRNGHLKVVKYLVSLGANIRT 197 Score = 47.0 bits (110), Expect = 4e-05 Identities = 29/87 (33%), Positives = 50/87 (57%) Frame = +3 Query: 306 AAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKG 485 A+ GH++VVK L + +AS+ G LEVV+ L+ GA+++AK+ Sbjct: 326 ASTNGHLEVVKYLVGQ---GADIRTGDDYAVRWASRGGCLEVVKYLVDQGANIRAKDDY- 381 Query: 486 FTALHFAAQNSHLELVKYLVRRGVDIT 566 A+ +A++ HLE+VK+L+ +G +T Sbjct: 382 --AVKWASEKGHLEIVKFLISQGAVLT 406 Score = 47.0 bits (110), Expect = 4e-05 Identities = 30/87 (34%), Positives = 45/87 (51%), Gaps = 3/87 (3%) Frame = +3 Query: 312 WA---GHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRK 482 WA GH+ VVK L I +AS+ G+L +V L++ GA ++A N Sbjct: 175 WASRNGHLKVVKYLVS---LGANIRTENDYAIKYASENGYLRIVEYLVSQGADIRADNDY 231 Query: 483 GFTALHFAAQNSHLELVKYLVRRGVDI 563 A+ A+ N H E+V+YLV +G +I Sbjct: 232 ---AVGLASSNGHFEVVEYLVSQGANI 255 Score = 43.5 bits (101), Expect = 4e-04 Identities = 22/50 (44%), Positives = 31/50 (62%) Frame = +3 Query: 396 IHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLV 545 + AS GH EVV L++ GA+++ N A+ A+ N HLE+VKYLV Sbjct: 233 VGLASSNGHFEVVEYLVSQGANIRVDND---YAVRLASSNGHLEVVKYLV 279 Score = 40.0 bits (92), Expect = 0.005 Identities = 19/51 (37%), Positives = 34/51 (66%) Frame = +3 Query: 411 QKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 +K L +++ L++ GA +KA + A+ A+QN HLE+++YLV +G +I Sbjct: 88 KKNKLNIIKYLVSLGADIKAGDD---CAVQLASQNGHLEVIEYLVAQGANI 135 Score = 29.6 bits (65), Expect = 6.3 Identities = 14/27 (51%), Positives = 21/27 (77%) Frame = +3 Query: 396 IHFASQKGHLEVVRELLASGASVKAKN 476 + +AS+KGHLE+V+ L++ GA V KN Sbjct: 383 VKWASEKGHLEIVKFLISQGA-VLTKN 408
>DAPK1_MOUSE (Q80YE7) Death-associated protein kinase 1 (EC 2.7.11.1) (DAP| kinase 1) Length = 1442 Score = 59.7 bits (143), Expect = 6e-09 Identities = 36/123 (29%), Positives = 60/123 (48%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 ++ A+R G ++ L + + L+ +D+ T LH+AA GH DVV+ LC Sbjct: 416 IYWASRHGHVDTLKFL-NENKCPLDVKDKSGETALHVAARYGHADVVQLLCSFGSNPDFQ 474 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 +H A+ G+ V + L G +V KNR+G T L A+ + ++V+ L G Sbjct: 475 DKEEETPLHCAAWHGYYSVAKALCEVGCNVNIKNREGETPLLTASARGYHDIVECLAEHG 534 Query: 555 VDI 563 D+ Sbjct: 535 ADL 537 Score = 58.5 bits (140), Expect = 1e-08 Identities = 34/113 (30%), Positives = 58/113 (51%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AA G + ++LC+ +N ++R TPL A+ G+ D+V+CL +H Sbjct: 482 LHCAAWHGYYSVAKALCEVG-CNVNIKNREGETPLLTASARGYHDIVECLAEHGADLNAS 540 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELV 533 +H A ++ +EV++ LL G+ V ++R G T LH A ++ +V Sbjct: 541 DKDGHIALHLAVRRCQMEVIKTLLGHGSFVDFQDRHGNTPLHVACKDGSAPIV 593 Score = 51.2 bits (121), Expect = 2e-06 Identities = 35/120 (29%), Positives = 51/120 (42%) Frame = +3 Query: 189 LKLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXX 368 + LH A R +++L ++ +DR TPLH+A G +V LC+ Sbjct: 546 IALHLAVRRCQMEVIKTLLGHGSF-VDFQDRHGNTPLHVACKDGSAPIVVALCEASCNLD 604 Query: 369 XXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVR 548 +H A+ G L+VVR L GA+V+A G TA A H + L R Sbjct: 605 ISNKYGRTPLHLAANNGILDVVRYLCLMGANVEALTSDGKTAEDLAKAEQHEHVAGLLAR 664 Score = 48.5 bits (114), Expect = 1e-05 Identities = 26/97 (26%), Positives = 50/97 (51%) Frame = +3 Query: 264 LNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVREL 443 +N ++ PL +AA G++ +++ L K I++AS+ GH++ ++ L Sbjct: 372 VNQPNKHGTPPLLIAAGCGNIQMLQLLIKRGSRIDVQDKGGSNAIYWASRHGHVDTLKFL 431 Query: 444 LASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 + + K++ G TALH AA+ H ++V+ L G Sbjct: 432 NENKCPLDVKDKSGETALHVAARYGHADVVQLLCSFG 468 Score = 44.7 bits (104), Expect = 2e-04 Identities = 25/100 (25%), Positives = 52/100 (52%) Frame = +3 Query: 264 LNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVREL 443 ++ +D+ ++ A+ GHVD +K L ++K +H A++ GH +VV+ L Sbjct: 405 IDVQDKGGSNAIYWASRHGHVDTLKFLNENKCPLDVKDKSGETALHVAARYGHADVVQLL 464 Query: 444 LASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 + G++ ++++ T LH AA + + + K L G ++ Sbjct: 465 CSFGSNPDFQDKEEETPLHCAAWHGYYSVAKALCEVGCNV 504
>PSD10_MOUSE (Q9Z2X2) 26S proteasome non-ATPase regulatory subunit 10 (26S| proteasome regulatory subunit p28) (Gankyrin) Length = 231 Score = 59.3 bits (142), Expect = 7e-09 Identities = 37/118 (31%), Positives = 55/118 (46%) Frame = +3 Query: 207 ARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXX 386 A SG ++ +D D+ SRT LH A AGH ++V+ L + Sbjct: 14 AYSGKLDELKERILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAG 73 Query: 387 XXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVD 560 +H A+ G E+V+ LL GA V A N+ G T LH+AA + E+ L+ G + Sbjct: 74 WSPLHIAASAGRDEIVKALLVKGAHVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGAN 131 Score = 56.6 bits (135), Expect = 5e-08 Identities = 37/117 (31%), Positives = 56/117 (47%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH A +G VE L + +N +D +PLH+AA AG ++VK L Sbjct: 44 LHWACSAGHTEIVEFLLQLG-VPVNDKDDAGWSPLHIAASAGRDEIVKALLVKGAHVNAV 102 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLV 545 +H+A+ K E+ LL GA+ AK+ TA+H AA +L++V L+ Sbjct: 103 NQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYDATAMHRAAAKGNLKMVHILL 159 Score = 49.7 bits (117), Expect = 6e-06 Identities = 36/123 (29%), Positives = 57/123 (46%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AA +G V++L +N+ ++ TPLH AA ++ L + Sbjct: 77 LHIAASAGRDEIVKALLVKGA-HVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAK 135 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 +H A+ KG+L++V LL AS ++ +G T LH A +E K+LV +G Sbjct: 136 DHYDATAMHRAAAKGNLKMVHILLFYKASTNIQDTEGNTPLHLACDEERVEEAKFLVTQG 195 Query: 555 VDI 563 I Sbjct: 196 ASI 198 Score = 44.3 bits (103), Expect = 2e-04 Identities = 26/86 (30%), Positives = 41/86 (47%), Gaps = 1/86 (1%) Frame = +3 Query: 309 AWAGHVDVVK-CLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKG 485 A++G +D +K + K +H+A GH E+V LL G V K+ G Sbjct: 14 AYSGKLDELKERILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAG 73 Query: 486 FTALHFAAQNSHLELVKYLVRRGVDI 563 ++ LH AA E+VK L+ +G + Sbjct: 74 WSPLHIAASAGRDEIVKALLVKGAHV 99 Score = 36.2 bits (82), Expect = 0.067 Identities = 20/80 (25%), Positives = 37/80 (46%) Frame = +3 Query: 267 NSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELL 446 +++D T +H AA G++ +V L +K +H A + +E + L+ Sbjct: 133 DAKDHYDATAMHRAAAKGNLKMVHILLFYKASTNIQDTEGNTPLHLACDEERVEEAKFLV 192 Query: 447 ASGASVKAKNRKGFTALHFA 506 GAS+ +N++ T L A Sbjct: 193 TQGASIYIENKEEKTPLQVA 212
>YR901_MIMIV (Q5UQZ7) Putative ankyrin repeat protein R901| Length = 361 Score = 58.9 bits (141), Expect = 1e-08 Identities = 41/120 (34%), Positives = 65/120 (54%) Frame = +3 Query: 204 AARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXX 383 A+R+G VE L S +++ D L+ + A+ GH++VVK L Sbjct: 146 ASRNGHIEVVEYLV-SQGANISAEDNLA---IRWASQNGHLEVVKYLVS---LNANIRAD 198 Query: 384 XXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 + +ASQ GHLE+V+ L+ GA+++A + A+ +A+ N HLE+VKYLV + DI Sbjct: 199 NDYAVRWASQNGHLEIVKYLVGQGANIRANDD---YAVRWASINGHLEVVKYLVSQDADI 255 Score = 57.8 bits (138), Expect = 2e-08 Identities = 35/87 (40%), Positives = 51/87 (58%), Gaps = 3/87 (3%) Frame = +3 Query: 312 WA---GHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRK 482 WA GH++VV+ L I +ASQ GHLEVV+ L++ A+++A N Sbjct: 145 WASRNGHIEVVEYLVSQ---GANISAEDNLAIRWASQNGHLEVVKYLVSLNANIRADNDY 201 Query: 483 GFTALHFAAQNSHLELVKYLVRRGVDI 563 A+ +A+QN HLE+VKYLV +G +I Sbjct: 202 ---AVRWASQNGHLEIVKYLVGQGANI 225 Score = 55.8 bits (133), Expect = 8e-08 Identities = 34/87 (39%), Positives = 48/87 (55%), Gaps = 3/87 (3%) Frame = +3 Query: 312 WA---GHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRK 482 WA GH++VVK L + AS+ GHL+VV L++SGA + +N Sbjct: 235 WASINGHLEVVKYLVSQDADIRALDNSA---VKCASRNGHLKVVEYLVSSGADITVENN- 290 Query: 483 GFTALHFAAQNSHLELVKYLVRRGVDI 563 A+ A++N HLE+VKYLV +G DI Sbjct: 291 --CAIGLASRNGHLEVVKYLVAQGTDI 315 Score = 55.1 bits (131), Expect = 1e-07 Identities = 42/125 (33%), Positives = 66/125 (52%), Gaps = 2/125 (1%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCD--SDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXX 368 L K+++ G VE L +D +LN+ L LA+ GH++VV+ L Sbjct: 83 LIKSSKKGQLKIVECLVSLGADIKSLNN------CALGLASENGHLEVVEYLVGQ---GA 133 Query: 369 XXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVR 548 I +AS+ GH+EVV L++ GA++ A++ A+ +A+QN HLE+VKYLV Sbjct: 134 NVRSNKNYAIIWASRNGHIEVVEYLVSQGANISAEDN---LAIRWASQNGHLEVVKYLVS 190 Query: 549 RGVDI 563 +I Sbjct: 191 LNANI 195 Score = 54.3 bits (129), Expect = 2e-07 Identities = 35/94 (37%), Positives = 49/94 (52%) Frame = +3 Query: 282 LSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGAS 461 L + + A+ GH+ VV+ L I AS+ GHLEVV+ L+A G Sbjct: 258 LDNSAVKCASRNGHLKVVEYLVS---SGADITVENNCAIGLASRNGHLEVVKYLVAQGTD 314 Query: 462 VKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 ++A+N A+ A+ N HLE+VKYLV G DI Sbjct: 315 IRAENN---YAIKLASLNGHLEVVKYLVSVGADI 345 Score = 51.6 bits (122), Expect = 2e-06 Identities = 39/130 (30%), Positives = 67/130 (51%), Gaps = 3/130 (2%) Frame = +3 Query: 186 DLKLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWA---GHVDVVKCLCKHK 356 +L + A+++G V+ L ++LN+ R + WA GH+++VK L Sbjct: 170 NLAIRWASQNGHLEVVKYL-----VSLNANIRADND--YAVRWASQNGHLEIVKYLVGQ- 221 Query: 357 XXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVK 536 + +AS GHLEVV+ L++ A ++A + +A+ A++N HL++V+ Sbjct: 222 --GANIRANDDYAVRWASINGHLEVVKYLVSQDADIRALDN---SAVKCASRNGHLKVVE 276 Query: 537 YLVRRGVDIT 566 YLV G DIT Sbjct: 277 YLVSSGADIT 286 Score = 47.8 bits (112), Expect = 2e-05 Identities = 27/83 (32%), Positives = 46/83 (55%) Frame = +3 Query: 318 GHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTAL 497 G + +V+CL + AS+ GHLEVV L+ GA+V++ A+ Sbjct: 90 GQLKIVECLVS---LGADIKSLNNCALGLASENGHLEVVEYLVGQGANVRSNKNY---AI 143 Query: 498 HFAAQNSHLELVKYLVRRGVDIT 566 +A++N H+E+V+YLV +G +I+ Sbjct: 144 IWASRNGHIEVVEYLVSQGANIS 166 Score = 37.4 bits (85), Expect = 0.030 Identities = 32/93 (34%), Positives = 43/93 (46%), Gaps = 2/93 (2%) Frame = +3 Query: 204 AARSGDAAAVESLCDS--DPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXX 377 A+R+G VE L S D N+ + LA+ GH++VVK L Sbjct: 266 ASRNGHLKVVEYLVSSGADITVENN------CAIGLASRNGHLEVVKYLVAQ---GTDIR 316 Query: 378 XXXXXXIHFASQKGHLEVVRELLASGASVKAKN 476 I AS GHLEVV+ L++ GA +KA N Sbjct: 317 AENNYAIKLASLNGHLEVVKYLVSVGADIKADN 349
>ASB2_HUMAN (Q96Q27) Ankyrin repeat and SOCS box protein 2 (ASB-2)| Length = 587 Score = 58.9 bits (141), Expect = 1e-08 Identities = 42/160 (26%), Positives = 66/160 (41%), Gaps = 33/160 (20%) Frame = +3 Query: 189 LKLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVD------------- 329 L LH+AA G ++ L + P ++ R T ++LA GH+D Sbjct: 92 LPLHEAAYYGQVGCLKVLQRAYPGTIDQRTLQEETAVYLATCRGHLDCLLSLLQAGAEPD 151 Query: 330 --------------------VVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLA 449 VK L +H +H + + LEV++ L++ Sbjct: 152 ISNKSRETPLYKACERKNAEAVKILVQHNADTNHRCNRGWTALHESVSRNDLEVMQILVS 211 Query: 450 SGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDITT 569 GA V++KN G T L AAQ+ LE +++L + G DI T Sbjct: 212 GGAKVESKNAYGITPLFVAAQSGQLEALRFLAKYGADINT 251 Score = 51.2 bits (121), Expect = 2e-06 Identities = 30/117 (25%), Positives = 55/117 (47%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH++ D ++ L S + S++ TPL +AA +G ++ ++ L K+ Sbjct: 194 LHESVSRNDLEVMQILV-SGGAKVESKNAYGITPLFVAAQSGQLEALRFLAKYGADINTQ 252 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLV 545 ++ A + H EVV LL+ GA N+ G LH A++ + +V+ L+ Sbjct: 253 ASDNASALYEACKNEHEEVVEFLLSQGADANKTNKDGLLPLHIASKKGNYRIVQMLL 309 Score = 46.6 bits (109), Expect = 5e-05 Identities = 33/122 (27%), Positives = 55/122 (45%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 L+KA +A AV+ L + N R T LH + ++V++ L Sbjct: 161 LYKACERKNAEAVKILVQHNA-DTNHRCNRGWTALHESVSRNDLEVMQILVSGGAKVESK 219 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 + A+Q G LE +R L GA + + +AL+ A +N H E+V++L+ +G Sbjct: 220 NAYGITPLFVAAQSGQLEALRFLAKYGADINTQASDNASALYEACKNEHEEVVEFLLSQG 279 Query: 555 VD 560 D Sbjct: 280 AD 281 Score = 33.1 bits (74), Expect = 0.57 Identities = 35/137 (25%), Positives = 57/137 (41%), Gaps = 12/137 (8%) Frame = +3 Query: 189 LKLHKAARSGDAAAVESLCDSDPLALNSRDRLSRT---PLHLAAWAGHVDVVKCLCKHK- 356 L LH A++ G+ V+ L L + SR R+ R+ PLHLAA H +V++ L + Sbjct: 291 LPLHIASKKGNYRIVQML-----LPVTSRTRIRRSGVSPLHLAAERNHDEVLEALLSARF 345 Query: 357 --------XXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQ 512 ++FA ++ LL GA NR + L A + Sbjct: 346 DVNTPLAPERARLYEDRRSSALYFAVVNNNVYATELLLQHGAD---PNRDVISPLLVAIR 402 Query: 513 NSHLELVKYLVRRGVDI 563 + L ++ L+ G +I Sbjct: 403 HGCLRTMQLLLDHGANI 419
>YR911_MIMIV (Q5UR04) Putative ankyrin repeat protein R911| Length = 467 Score = 58.5 bits (140), Expect = 1e-08 Identities = 33/87 (37%), Positives = 51/87 (58%) Frame = +3 Query: 303 LAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRK 482 LA++ G+++VVK L + AS+ GH+EVV L++ GA++++ N Sbjct: 176 LASYYGYLEVVKYLVSQ---GADIRSDNDYAVRMASRNGHIEVVEYLVSQGANIRSDNDY 232 Query: 483 GFTALHFAAQNSHLELVKYLVRRGVDI 563 A+ A+QN HLE+VKYLV +G DI Sbjct: 233 ---AVRLASQNGHLEVVKYLVSQGADI 256 Score = 58.2 bits (139), Expect = 2e-08 Identities = 33/89 (37%), Positives = 51/89 (57%) Frame = +3 Query: 297 LHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKN 476 + +A+ GH++VV+ L + ASQ GHLEVV+ L++ GA +K+ N Sbjct: 204 VRMASRNGHIEVVEYLVSQ---GANIRSDNDYAVRLASQNGHLEVVKYLVSQGADIKSDN 260 Query: 477 RKGFTALHFAAQNSHLELVKYLVRRGVDI 563 A+ A+QN HLE+V+YLV +G +I Sbjct: 261 D---YAVRLASQNGHLEVVEYLVTQGTNI 286 Score = 54.7 bits (130), Expect = 2e-07 Identities = 40/126 (31%), Positives = 63/126 (50%) Frame = +3 Query: 186 DLKLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXX 365 D + A+++G V+ L + D R LA+ GH++VV+ L Sbjct: 231 DYAVRLASQNGHLEVVKYLVSQGADIKSDNDYAVR----LASQNGHLEVVEYLVTQ---G 283 Query: 366 XXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLV 545 + +AS+ G+LEVV+ L++ GA + A N A+ +A++N HLE+VKYLV Sbjct: 284 TNIRVNNNYAVEWASKNGNLEVVKYLISQGADIIADNN---FAVRWASRNGHLEVVKYLV 340 Query: 546 RRGVDI 563 G DI Sbjct: 341 SLGADI 346 Score = 53.9 bits (128), Expect = 3e-07 Identities = 34/87 (39%), Positives = 50/87 (57%), Gaps = 3/87 (3%) Frame = +3 Query: 312 WA---GHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRK 482 WA G+++VVK L + +AS+ GHLEVV+ L++ GA +K+ N Sbjct: 296 WASKNGNLEVVKYLISQ---GADIIADNNFAVRWASRNGHLEVVKYLVSLGADIKSDND- 351 Query: 483 GFTALHFAAQNSHLELVKYLVRRGVDI 563 A+ +A+ N HLE+VKYLV +G DI Sbjct: 352 --YAVRWASGNGHLEVVKYLVSQGSDI 376 Score = 52.8 bits (125), Expect = 7e-07 Identities = 30/87 (34%), Positives = 49/87 (56%), Gaps = 3/87 (3%) Frame = +3 Query: 312 WA---GHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRK 482 WA GH++VVK L + +AS GHLEVV+ L++ G+ ++ +N Sbjct: 326 WASRNGHLEVVKYLVS---LGADIKSDNDYAVRWASGNGHLEVVKYLVSQGSDIRVEND- 381 Query: 483 GFTALHFAAQNSHLELVKYLVRRGVDI 563 A+ +A++N H +++KYLV +G DI Sbjct: 382 --YAVRWASRNGHFDVIKYLVSQGADI 406 Score = 52.4 bits (124), Expect = 9e-07 Identities = 32/87 (36%), Positives = 49/87 (56%) Frame = +3 Query: 303 LAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRK 482 L++ GH++VVK L + +AS GHLEVV+ L++ GA+++A N Sbjct: 116 LSSQNGHLEVVKYLVNQ---GSDIRAENDYAVRWASGNGHLEVVKYLVSQGANIRADNDH 172 Query: 483 GFTALHFAAQNSHLELVKYLVRRGVDI 563 A+ A+ +LE+VKYLV +G DI Sbjct: 173 ---AIGLASYYGYLEVVKYLVSQGADI 196 Score = 52.0 bits (123), Expect = 1e-06 Identities = 30/87 (34%), Positives = 49/87 (56%), Gaps = 3/87 (3%) Frame = +3 Query: 312 WA---GHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRK 482 WA GH++VVK L + +AS+ GH +V++ L++ GA +++ N Sbjct: 356 WASGNGHLEVVKYLVSQ---GSDIRVENDYAVRWASRNGHFDVIKYLVSQGADIRSDNDY 412 Query: 483 GFTALHFAAQNSHLELVKYLVRRGVDI 563 A+ +A++N HLE+VK+LV G DI Sbjct: 413 ---AVKWASENGHLEVVKFLVSLGADI 436 Score = 51.2 bits (121), Expect = 2e-06 Identities = 31/84 (36%), Positives = 48/84 (57%), Gaps = 3/84 (3%) Frame = +3 Query: 312 WA---GHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRK 482 WA GH DV+K L + +AS+ GHLEVV+ L++ GA +KA++ Sbjct: 386 WASRNGHFDVIKYLVSQ---GADIRSDNDYAVKWASENGHLEVVKFLVSLGADIKAEDD- 441 Query: 483 GFTALHFAAQNSHLELVKYLVRRG 554 A+ +A++ HLE+V+YLV +G Sbjct: 442 --YAVRWASEKGHLEVVEYLVSQG 463 Score = 50.1 bits (118), Expect = 4e-06 Identities = 25/56 (44%), Positives = 39/56 (69%) Frame = +3 Query: 396 IHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 + +SQ GHLEVV+ L+ G+ ++A+N A+ +A+ N HLE+VKYLV +G +I Sbjct: 114 VGLSSQNGHLEVVKYLVNQGSDIRAEND---YAVRWASGNGHLEVVKYLVSQGANI 166 Score = 48.9 bits (115), Expect = 1e-05 Identities = 31/87 (35%), Positives = 48/87 (55%), Gaps = 3/87 (3%) Frame = +3 Query: 312 WA---GHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRK 482 WA GH++VVK L I AS G+LEVV+ L++ GA +++ N Sbjct: 146 WASGNGHLEVVKYLVSQ---GANIRADNDHAIGLASYYGYLEVVKYLVSQGADIRSDND- 201 Query: 483 GFTALHFAAQNSHLELVKYLVRRGVDI 563 A+ A++N H+E+V+YLV +G +I Sbjct: 202 --YAVRMASRNGHIEVVEYLVSQGANI 226 Score = 42.4 bits (98), Expect = 0.001 Identities = 22/50 (44%), Positives = 34/50 (68%) Frame = +3 Query: 414 KGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 + LE+V+ L++ GA ++A N A+ ++QN HLE+VKYLV +G DI Sbjct: 90 ENQLEIVKFLVSLGADIRAGNDY---AVGLSSQNGHLEVVKYLVNQGSDI 136 Score = 32.7 bits (73), Expect = 0.74 Identities = 20/52 (38%), Positives = 27/52 (51%), Gaps = 3/52 (5%) Frame = +3 Query: 312 WA---GHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGA 458 WA GH++VVK L + +AS+KGHLEVV L++ GA Sbjct: 416 WASENGHLEVVKFLVS---LGADIKAEDDYAVRWASEKGHLEVVEYLVSQGA 464
>ASB15_BOVIN (Q8HXA6) Ankyrin repeat and SOCS box protein 15 (ASB-15)| Length = 588 Score = 58.5 bits (140), Expect = 1e-08 Identities = 30/99 (30%), Positives = 53/99 (53%) Frame = +3 Query: 267 NSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELL 446 N+++ TPL LA G D+V L KH +H A+++GH +++ LL Sbjct: 138 NTKNDKGETPLLLAIKRGSYDMVSALLKHNTSLDQPCVKRWSAMHEAAKQGHKDIIALLL 197 Query: 447 ASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 +G +V K+ G T L AA+ H +++++L+ +G D+ Sbjct: 198 NNGGNVHLKDGFGVTPLGVAAEYGHCDVLEHLIHKGGDV 236
>YR873_MIMIV (Q5UP39) Putative ankyrin repeat protein R873| Length = 468 Score = 58.5 bits (140), Expect = 1e-08 Identities = 34/89 (38%), Positives = 55/89 (61%), Gaps = 1/89 (1%) Frame = +3 Query: 306 AAWAGHVDVVKCL-CKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRK 482 A+ GH++VVK L CK + +AS KGHL+VV+ L++ G+ ++++N Sbjct: 116 ASHHGHIEVVKYLVCK----GANFRANNDKAVRWASDKGHLDVVKYLVSQGSDIRSEND- 170 Query: 483 GFTALHFAAQNSHLELVKYLVRRGVDITT 569 ++ +A+ N HLE+VKYLV +GV+I T Sbjct: 171 --CSICWASGNGHLEMVKYLVSQGVNIRT 197 Score = 53.5 bits (127), Expect = 4e-07 Identities = 33/87 (37%), Positives = 48/87 (55%), Gaps = 3/87 (3%) Frame = +3 Query: 312 WA---GHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRK 482 WA GH+DVVK L I +AS GHLE+V+ L++ G +++ + Sbjct: 145 WASDKGHLDVVKYLVSQ---GSDIRSENDCSICWASGNGHLEMVKYLVSQGVNIRTNDD- 200 Query: 483 GFTALHFAAQNSHLELVKYLVRRGVDI 563 A+ A++N HLE+VKYLV +G DI Sbjct: 201 --WAIRLASENGHLEVVKYLVSQGADI 225 Score = 53.1 bits (126), Expect = 5e-07 Identities = 31/91 (34%), Positives = 54/91 (59%) Frame = +3 Query: 297 LHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKN 476 + LA+ GH++VVK L I +AS GHLE+V+ L++ +++ A++ Sbjct: 203 IRLASENGHLEVVKYLVSQ---GADIRSQDDHAIKWASGNGHLEMVKYLVSQSSNIIAED 259 Query: 477 RKGFTALHFAAQNSHLELVKYLVRRGVDITT 569 A+ +A++N HLE++KYLV +G +IT+ Sbjct: 260 NY---AVRWASENGHLEVIKYLVSQGSNITS 287 Score = 51.6 bits (122), Expect = 2e-06 Identities = 28/91 (30%), Positives = 51/91 (56%), Gaps = 3/91 (3%) Frame = +3 Query: 300 HLAAWA---GHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKA 470 H WA GH+++VK L + +AS+ GHLEV++ L++ G+++ + Sbjct: 231 HAIKWASGNGHLEMVKYLVSQSSNIIAEDNYA---VRWASENGHLEVIKYLVSQGSNITS 287 Query: 471 KNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 + + A++N H+++VKYLV +GV+I Sbjct: 288 N----YYTIIAASKNGHIDIVKYLVSQGVNI 314 Score = 50.1 bits (118), Expect = 4e-06 Identities = 28/86 (32%), Positives = 49/86 (56%), Gaps = 3/86 (3%) Frame = +3 Query: 312 WA---GHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRK 482 WA GH++V+K L I AS+ GH+++V+ L++ G +++ + Sbjct: 265 WASENGHLEVIKYLVSQ----GSNITSNYYTIIAASKNGHIDIVKYLVSQGVNIRDCDS- 319 Query: 483 GFTALHFAAQNSHLELVKYLVRRGVD 560 +A+ A++N HLE+VKYLV +G+D Sbjct: 320 --SAVQIASENGHLEVVKYLVSQGID 343 Score = 48.1 bits (113), Expect = 2e-05 Identities = 26/87 (29%), Positives = 48/87 (55%) Frame = +3 Query: 294 PLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAK 473 P+ +A+ G + VVK + +++KGH+EVV+ L+ +GA+++A Sbjct: 381 PVRMASHCGRLGVVKYFVSQ---GADVRAEDDYAVRMSAEKGHIEVVKFLVDNGANIRAD 437 Query: 474 NRKGFTALHFAAQNSHLELVKYLVRRG 554 N A+ A++N H+++V+YLV G Sbjct: 438 ND---YAVRLASENGHIKIVEYLVSMG 461 Score = 47.8 bits (112), Expect = 2e-05 Identities = 28/81 (34%), Positives = 41/81 (50%) Frame = +3 Query: 318 GHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTAL 497 GH+D+VK L + AS+ GHLEVV+ L++ G + + F Sbjct: 299 GHIDIVKYLVSQ---GVNIRDCDSSAVQIASENGHLEVVKYLVSQGIDFREHDDLTFD-- 353 Query: 498 HFAAQNSHLELVKYLVRRGVD 560 A + H+E+VKYLV +GVD Sbjct: 354 -MALRKGHVEIVKYLVGQGVD 373 Score = 40.4 bits (93), Expect = 0.004 Identities = 27/87 (31%), Positives = 44/87 (50%) Frame = +3 Query: 303 LAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRK 482 +A GHV++VK L + AS G L VV+ ++ GA V+A++ Sbjct: 354 MALRKGHVEIVKYLVGQ---GVDFRVYDDYPVRMASHCGRLGVVKYFVSQGADVRAEDDY 410 Query: 483 GFTALHFAAQNSHLELVKYLVRRGVDI 563 A+ +A+ H+E+VK+LV G +I Sbjct: 411 ---AVRMSAEKGHIEVVKFLVDNGANI 434
>YL482_MIMIV (Q5UQF2) Putative ankyrin repeat protein L482 (Fragment)| Length = 109 Score = 58.2 bits (139), Expect = 2e-08 Identities = 32/82 (39%), Positives = 47/82 (57%) Frame = +3 Query: 318 GHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTAL 497 GH+++VKCL I AS+KGHLEVV+ L+ A+++++N A+ Sbjct: 9 GHIEIVKCLVN---LGANITTNNNYAIIQASEKGHLEVVKYLVGQNANIRSENN---LAV 62 Query: 498 HFAAQNSHLELVKYLVRRGVDI 563 A+ N HLE+V+YLV G DI Sbjct: 63 RLASGNGHLEVVEYLVNLGADI 84 Score = 47.8 bits (112), Expect = 2e-05 Identities = 29/80 (36%), Positives = 43/80 (53%) Frame = +3 Query: 306 AAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKG 485 A+ GH++VVK L + AS GHLEVV L+ GA ++++N Sbjct: 35 ASEKGHLEVVKYLVGQNANIRSENNLA---VRLASGNGHLEVVEYLVNLGADIRSENN-- 89 Query: 486 FTALHFAAQNSHLELVKYLV 545 A+ A+QN HLE+++YLV Sbjct: 90 -YAIQSASQNGHLEVIEYLV 108 Score = 39.3 bits (90), Expect = 0.008 Identities = 21/52 (40%), Positives = 33/52 (63%) Frame = +3 Query: 408 SQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 S KGH+E+V+ L+ GA++ N A+ A++ HLE+VKYLV + +I Sbjct: 6 SGKGHIEIVKCLVNLGANITTNNN---YAIIQASEKGHLEVVKYLVGQNANI 54
>YL025_MIMIV (Q5UPA0) Putative ankyrin repeat protein L25| Length = 326 Score = 58.2 bits (139), Expect = 2e-08 Identities = 34/86 (39%), Positives = 49/86 (56%) Frame = +3 Query: 306 AAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKG 485 A+ GH+ +VK L K + +AS+ GHLEVV+ L+ GA+ +A+N Sbjct: 133 ASEGGHLQIVKYLVKK---GADIHAEDDEALKWASRSGHLEVVKYLVEKGANFRAENDY- 188 Query: 486 FTALHFAAQNSHLELVKYLVRRGVDI 563 AL +A + HLE+VKYLV +G DI Sbjct: 189 --ALRWACEKGHLEIVKYLVEKGADI 212 Score = 57.0 bits (136), Expect = 4e-08 Identities = 33/89 (37%), Positives = 52/89 (58%) Frame = +3 Query: 297 LHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKN 476 L A+ +GH++VVK L + + +A +KGHLE+V+ L+ GA + A++ Sbjct: 160 LKWASRSGHLEVVKYLVEK---GANFRAENDYALRWACEKGHLEIVKYLVEKGADIHAED 216 Query: 477 RKGFTALHFAAQNSHLELVKYLVRRGVDI 563 AL +A+++ HLE+VKYLV G DI Sbjct: 217 EY---ALRWASRSGHLEVVKYLVENGADI 242 Score = 54.3 bits (129), Expect = 2e-07 Identities = 31/89 (34%), Positives = 54/89 (60%) Frame = +3 Query: 294 PLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAK 473 PL A+ GH++VVK L ++ + +AS+ GHL++V+ L+ GA + A+ Sbjct: 100 PLKWASKNGHLEVVKYLVEN----GADIHAYNELVVYASEGGHLQIVKYLVKKGADIHAE 155 Query: 474 NRKGFTALHFAAQNSHLELVKYLVRRGVD 560 + + AL +A+++ HLE+VKYLV +G + Sbjct: 156 DDE---ALKWASRSGHLEVVKYLVEKGAN 181 Score = 53.1 bits (126), Expect = 5e-07 Identities = 41/126 (32%), Positives = 60/126 (47%) Frame = +3 Query: 186 DLKLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXX 365 D L A+RSG V+ L + D L A GH+++VK L + Sbjct: 157 DEALKWASRSGHLEVVKYLVEKGANFRAENDYA----LRWACEKGHLEIVKYLVEK---G 209 Query: 366 XXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLV 545 + +AS+ GHLEVV+ L+ +GA + A N G L A++N HL +VKYL+ Sbjct: 210 ADIHAEDEYALRWASRSGHLEVVKYLVENGADIHACNDYG---LRKASRNRHLNVVKYLM 266 Query: 546 RRGVDI 563 G +I Sbjct: 267 ENGANI 272 Score = 51.2 bits (121), Expect = 2e-06 Identities = 29/86 (33%), Positives = 50/86 (58%) Frame = +3 Query: 306 AAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKG 485 A+ G++++V L K+ + +AS+ GHLEVV+ L+ +GA + A N Sbjct: 74 ASKGGYLELVNLLIKN---GADIHVNDDAPLKWASKNGHLEVVKYLVENGADIHAYNE-- 128 Query: 486 FTALHFAAQNSHLELVKYLVRRGVDI 563 + +A++ HL++VKYLV++G DI Sbjct: 129 --LVVYASEGGHLQIVKYLVKKGADI 152 Score = 47.8 bits (112), Expect = 2e-05 Identities = 31/89 (34%), Positives = 49/89 (55%) Frame = +3 Query: 297 LHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKN 476 L A+ +GH++VVK L ++ + AS+ HL VV+ L+ +GA++ AK+ Sbjct: 220 LRWASRSGHLEVVKYLVEN---GADIHACNDYGLRKASRNRHLNVVKYLMENGANIHAKD 276 Query: 477 RKGFTALHFAAQNSHLELVKYLVRRGVDI 563 AL A+ N H +LVK+LV G +I Sbjct: 277 DY---ALRLASVNGHFKLVKFLVENGANI 302 Score = 45.1 bits (105), Expect = 1e-04 Identities = 23/54 (42%), Positives = 35/54 (64%) Frame = +3 Query: 402 FASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 +AS+ G+LE+V L+ +GA + + L +A++N HLE+VKYLV G DI Sbjct: 73 YASKGGYLELVNLLIKNGADIHVNDD---APLKWASKNGHLEVVKYLVENGADI 123 Score = 35.4 bits (80), Expect = 0.11 Identities = 28/93 (30%), Positives = 48/93 (51%) Frame = +3 Query: 285 SRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASV 464 S PL A+ GHV+VV L ++ F K +L+VV+ L+ +G+++ Sbjct: 12 SEYPLRWASTEGHVEVVIYLVENGADLNVLKL-------FYVDK-YLQVVKYLIENGSNI 63 Query: 465 KAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 + FT + +A++ +LELV L++ G DI Sbjct: 64 HVDDE--FTLI-YASKGGYLELVNLLIKNGADI 93 Score = 35.0 bits (79), Expect = 0.15 Identities = 34/118 (28%), Positives = 55/118 (46%), Gaps = 2/118 (1%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDS--DPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXX 368 L A+RSG V+ L ++ D A N L A+ H++VVK L ++ Sbjct: 220 LRWASRSGHLEVVKYLVENGADIHACNDYG------LRKASRNRHLNVVKYLMEN---GA 270 Query: 369 XXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYL 542 + AS GH ++V+ L+ +GA++ AKN + AL H+++V YL Sbjct: 271 NIHAKDDYALRLASVNGHFKLVKFLVENGANIHAKNNE---ALIRPLGEGHIKIVTYL 325
>ANKR5_MOUSE (Q9D2J7) Ankyrin repeat domain-containing protein 5| Length = 775 Score = 58.2 bits (139), Expect = 2e-08 Identities = 33/115 (28%), Positives = 61/115 (53%) Frame = +3 Query: 210 RSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXX 389 ++GD A+++ ++ + ++ +D +TPL +A +G++DVVK L + Sbjct: 501 KAGDLASLKKAIETG-IPVDMKDNTYKTPLMIACASGNIDVVKFLIEKGANVNATDNFLW 559 Query: 390 XXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 +HFA G ++V L+ +GAS+ A + T L A ++ L+ VKYL+ G Sbjct: 560 TPLHFACHAGQQDIVELLVKAGASIDATSINNSTPLSRAIESCRLDTVKYLLDMG 614 Score = 46.6 bits (109), Expect = 5e-05 Identities = 31/101 (30%), Positives = 45/101 (44%) Frame = +3 Query: 204 AARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXX 383 A SG+ V+ L + +N+ D TPLH A AG D+V+ L K Sbjct: 532 ACASGNIDVVKFLIEKGA-NVNATDNFLWTPLHFACHAGQQDIVELLVKAGASIDATSIN 590 Query: 384 XXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFA 506 + A + L+ V+ LL GA + +NRKG A+ A Sbjct: 591 NSTPLSRAIESCRLDTVKYLLDMGAKFQIENRKGHAAMDIA 631 Score = 43.5 bits (101), Expect = 4e-04 Identities = 26/105 (24%), Positives = 49/105 (46%) Frame = +3 Query: 249 SDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLE 428 ++P A+N+ RT L ++ G +++V+ + + HFA++ G + Sbjct: 175 ANPNAINTST--GRTALMESSREGVLEIVRGILERGGEVNAYDNDRHHAAHFAAKGGFFD 232 Query: 429 VVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 +++ L A + G T LHFAA + KY+ +RG D+ Sbjct: 233 ILKLLFAYNGDMGLIGMDGNTPLHFAAMGGFADCCKYIAQRGCDL 277 Score = 30.0 bits (66), Expect = 4.8 Identities = 17/71 (23%), Positives = 28/71 (39%) Frame = +3 Query: 264 LNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVREL 443 +N+ D H AA G D++K L + +HFA+ G + + + Sbjct: 211 VNAYDNDRHHAAHFAAKGGFFDILKLLFAYNGDMGLIGMDGNTPLHFAAMGGFADCCKYI 270 Query: 444 LASGASVKAKN 476 G +K KN Sbjct: 271 AQRGCDLKWKN 281
>AKT1_ARATH (Q38998) Potassium channel AKT1| Length = 857 Score = 57.8 bits (138), Expect = 2e-08 Identities = 42/128 (32%), Positives = 62/128 (48%), Gaps = 5/128 (3%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCD--SDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXX 368 LH AA G V L + +DP N RD PL A GH VVK L +H Sbjct: 555 LHIAASKGTLNCVLLLLEYHADP---NCRDAEGSVPLWEAMVEGHEKVVKVLLEHGSTID 611 Query: 369 XXXXXXXXXIHFA---SQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKY 539 HFA +++G+L++++E++ G V G +ALH A ++E+VKY Sbjct: 612 AGDVG-----HFACTAAEQGNLKLLKEIVLHGGDVTRPRATGTSALHTAVCEENIEMVKY 666 Query: 540 LVRRGVDI 563 L+ +G D+ Sbjct: 667 LLEQGADV 674
>YR863_MIMIV (Q5UQJ2) Putative ankyrin repeat protein R863| Length = 514 Score = 57.8 bits (138), Expect = 2e-08 Identities = 41/126 (32%), Positives = 63/126 (50%) Frame = +3 Query: 186 DLKLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXX 365 D + A+ +G V+ L D + D R A+ GH++VVK L Sbjct: 387 DCAIKLASENGHLEVVKYLVSQDADIRVNNDYAIRW----ASRNGHIEVVKYLVSQ---G 439 Query: 366 XXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLV 545 + AS+ GHLEVV+ L+ GA+VKA+N A+ +A++N H+ +VKYLV Sbjct: 440 ADIRADNDYAVRMASENGHLEVVKYLVNLGANVKAQNN---YAVGWASRNGHIGVVKYLV 496 Query: 546 RRGVDI 563 +G D+ Sbjct: 497 SQGADV 502 Score = 56.6 bits (135), Expect = 5e-08 Identities = 35/89 (39%), Positives = 50/89 (56%) Frame = +3 Query: 297 LHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKN 476 + LA+ GH+DVVK L I AS+ GH+EVV L++ GA+VK+ N Sbjct: 210 VRLASENGHIDVVKYLVS---LGADIRADNNYAIRHASRGGHIEVVEYLVSLGANVKSCN 266 Query: 477 RKGFTALHFAAQNSHLELVKYLVRRGVDI 563 A+ FA++N HL +VKYL +G D+ Sbjct: 267 D---CAVKFASKNGHLGVVKYLASQGADV 292 Score = 55.1 bits (131), Expect = 1e-07 Identities = 32/86 (37%), Positives = 49/86 (56%) Frame = +3 Query: 306 AAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKG 485 A+ GH++VV+ L + FAS+ GHL VV+ L + GA V+++N Sbjct: 243 ASRGGHIEVVEYLVS---LGANVKSCNDCAVKFASKNGHLGVVKYLASQGADVRSENDYA 299 Query: 486 FTALHFAAQNSHLELVKYLVRRGVDI 563 F A++N HLE+V YLVR+GV++ Sbjct: 300 F---RMASENGHLEVVVYLVRQGVNV 322 Score = 49.7 bits (117), Expect = 6e-06 Identities = 34/125 (27%), Positives = 64/125 (51%) Frame = +3 Query: 186 DLKLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXX 365 D + A+++G V+ L + D R +A+ GH++VV L + Sbjct: 267 DCAVKFASKNGHLGVVKYLASQGADVRSENDYAFR----MASENGHLEVVVYLVRQ---G 319 Query: 366 XXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLV 545 + AS+ G+LE+V+ L++ GA++++KN A+ A++N HLE+V++LV Sbjct: 320 VNVRADNNYAVRMASENGYLEIVKFLVSQGANIRSKND---YAIQKASKNGHLEVVEHLV 376 Query: 546 RRGVD 560 +G + Sbjct: 377 NQGAN 381 Score = 49.3 bits (116), Expect = 8e-06 Identities = 29/91 (31%), Positives = 49/91 (53%), Gaps = 3/91 (3%) Frame = +3 Query: 300 HLAAWA---GHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKA 470 + WA GH++VVK L + +AS+ G+++VV+ L + A+++A Sbjct: 148 YAVVWASRNGHLEVVKYLVS---LGANIKVDDNFAVRWASRNGYIDVVKYLTSQDANIRA 204 Query: 471 KNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 N A+ A++N H+++VKYLV G DI Sbjct: 205 DNNY---AVRLASENGHIDVVKYLVSLGADI 232 Score = 48.5 bits (114), Expect = 1e-05 Identities = 31/89 (34%), Positives = 47/89 (52%) Frame = +3 Query: 297 LHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKN 476 + +A+ G++++VK L I AS+ GHLEVV L+ GA+ K+ Sbjct: 330 VRMASENGYLEIVKFLVSQ---GANIRSKNDYAIQKASKNGHLEVVEHLVNQGANFKSDY 386 Query: 477 RKGFTALHFAAQNSHLELVKYLVRRGVDI 563 A+ A++N HLE+VKYLV + DI Sbjct: 387 D---CAIKLASENGHLEVVKYLVSQDADI 412 Score = 47.8 bits (112), Expect = 2e-05 Identities = 24/56 (42%), Positives = 39/56 (69%) Frame = +3 Query: 396 IHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 + AS++G+LE+V+ L++ GA V+A A+ +A++N HLE+VKYLV G +I Sbjct: 120 VRLASERGYLEIVKYLVSQGADVRANKD---YAVVWASRNGHLEVVKYLVSLGANI 172 Score = 38.9 bits (89), Expect = 0.010 Identities = 17/51 (33%), Positives = 33/51 (64%) Frame = +3 Query: 411 QKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 +K L++++ L+ GA + +K + A+ A++ +LE+VKYLV +G D+ Sbjct: 95 EKRRLDIIQYLINIGADINSKKNR---AVRLASERGYLEIVKYLVSQGADV 142
>YL023_MIMIV (Q5UPA2) Putative ankyrin repeat protein L23| Length = 269 Score = 57.4 bits (137), Expect = 3e-08 Identities = 34/87 (39%), Positives = 48/87 (55%), Gaps = 3/87 (3%) Frame = +3 Query: 312 WA---GHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRK 482 WA GH+DVVK L + +AS GHLEVV+ L++ GA+++ +N Sbjct: 155 WASENGHIDVVKYLVSQNADIRADNDYA---VKWASSNGHLEVVKYLVSQGANIREQND- 210 Query: 483 GFTALHFAAQNSHLELVKYLVRRGVDI 563 A+ A+Q HLE+VKYL+ G DI Sbjct: 211 --YAIRLASQYGHLEVVKYLISLGADI 235 Score = 57.0 bits (136), Expect = 4e-08 Identities = 34/87 (39%), Positives = 48/87 (55%), Gaps = 3/87 (3%) Frame = +3 Query: 312 WA---GHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRK 482 WA GH++VVK L I ASQ GHLEVV+ L++ GA ++A N Sbjct: 185 WASSNGHLEVVKYLVSQ---GANIREQNDYAIRLASQYGHLEVVKYLISLGADIRADND- 240 Query: 483 GFTALHFAAQNSHLELVKYLVRRGVDI 563 A+ A++N H+E+V YL+ +G DI Sbjct: 241 --CAVRLASENGHIEIVNYLISQGADI 265 Score = 47.8 bits (112), Expect = 2e-05 Identities = 23/56 (41%), Positives = 39/56 (69%) Frame = +3 Query: 396 IHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 + +AS+ GHL+VV L++ GA +K+ G A+ +A++N H+++VKYLV + DI Sbjct: 123 VKWASKNGHLKVVEYLVSLGADIKSD---GDYAVRWASENGHIDVVKYLVSQNADI 175 Score = 37.0 bits (84), Expect = 0.039 Identities = 19/59 (32%), Positives = 31/59 (52%) Frame = +3 Query: 297 LHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAK 473 + LA+ GH++VVK L + AS+ GH+E+V L++ GA ++AK Sbjct: 213 IRLASQYGHLEVVKYLIS---LGADIRADNDCAVRLASENGHIEIVNYLISQGADIRAK 268 Score = 30.4 bits (67), Expect = 3.7 Identities = 14/41 (34%), Positives = 28/41 (68%) Frame = +3 Query: 441 LLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 +++ G ++A++ A+ +A++N HL++V+YLV G DI Sbjct: 108 MVSKGVDIRAEDDY---AVKWASKNGHLKVVEYLVSLGADI 145
>MIB1_MOUSE (Q80SY4) Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb| homolog 1) (DAPK-interacting protein 1) (DIP-1) Length = 1006 Score = 57.4 bits (137), Expect = 3e-08 Identities = 37/121 (30%), Positives = 56/121 (46%) Frame = +3 Query: 192 KLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXX 371 +L KAA +GD A VE L + +N + T + A+ GHVD++K L K Sbjct: 434 ELVKAAANGDVAKVEDLLKRPDVDVNGQCA-GHTAMQAASQNGHVDILKLLLKQNVDVEA 492 Query: 372 XXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRR 551 +H A+ V+ L A + A+N++ T LH A HL++VK L+ Sbjct: 493 EDKDGDRAVHHAAFGDEGAVIEVLHRGSADLNARNKRRQTPLHIAVNKGHLQVVKTLLDF 552 Query: 552 G 554 G Sbjct: 553 G 553 Score = 56.2 bits (134), Expect = 6e-08 Identities = 45/159 (28%), Positives = 63/159 (39%), Gaps = 36/159 (22%) Frame = +3 Query: 186 DLKLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXX 365 D +H AA GD AV + LN+R++ +TPLH+A GH+ VVK L Sbjct: 498 DRAVHHAA-FGDEGAVIEVLHRGSADLNARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHP 556 Query: 366 XXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGF------------------- 488 +H A K +++ LL +GA V N GF Sbjct: 557 SLQDSEGDTPLHDAISKKRDDILAVLLEAGADVTITNNNGFNALHHAALRGNPSAMRVLL 616 Query: 489 -----------------TALHFAAQNSHLELVKYLVRRG 554 TALH AA N+H+E+ + LV +G Sbjct: 617 SKLPRPWIVDEKKDDGYTALHLAALNNHVEVAELLVHQG 655 Score = 47.0 bits (110), Expect = 4e-05 Identities = 33/119 (27%), Positives = 56/119 (47%), Gaps = 3/119 (2%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDS--DPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKH-KXXX 365 LH AA G+ +A+ L P ++ + T LHLAA HV+V + L Sbjct: 600 LHHAALRGNPSAMRVLLSKLPRPWIVDEKKDDGYTALHLAALNNHVEVAELLVHQGNANL 659 Query: 366 XXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYL 542 +H A ++ H ++VR L+ +GA + +++ G T LH A ++ L ++ L Sbjct: 660 DIQNVNQQTALHLAVERQHTQIVRLLVRAGAKLDIQDKDGDTPLHEALRHHTLSQLRQL 718 Score = 39.3 bits (90), Expect = 0.008 Identities = 20/57 (35%), Positives = 32/57 (56%), Gaps = 1/57 (1%) Frame = +3 Query: 396 IHFASQKGHLEVVRELLASG-ASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 +H A+ H+EV L+ G A++ +N TALH A + H ++V+ LVR G + Sbjct: 636 LHLAALNNHVEVAELLVHQGNANLDIQNVNQQTALHLAVERQHTQIVRLLVRAGAKL 692 Score = 38.1 bits (87), Expect = 0.018 Identities = 24/86 (27%), Positives = 40/86 (46%) Frame = +3 Query: 306 AAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKG 485 AA G V V+ L K + ASQ GH+++++ LL V+A+++ G Sbjct: 438 AAANGDVAKVEDLLKRPDVDVNGQCAGHTAMQAASQNGHVDILKLLLKQNVDVEAEDKDG 497 Query: 486 FTALHFAAQNSHLELVKYLVRRGVDI 563 A+H AA +++ L R D+ Sbjct: 498 DRAVHHAAFGDEGAVIEVLHRGSADL 523
>MIB1_HUMAN (Q86YT6) Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb| homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2) Length = 1006 Score = 57.4 bits (137), Expect = 3e-08 Identities = 37/121 (30%), Positives = 56/121 (46%) Frame = +3 Query: 192 KLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXX 371 +L KAA +GD A VE L + +N + T + A+ GHVD++K L K Sbjct: 434 ELVKAAANGDVAKVEDLLKRPDVDVNGQCA-GHTAMQAASQNGHVDILKLLLKQNVDVEA 492 Query: 372 XXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRR 551 +H A+ V+ L A + A+N++ T LH A HL++VK L+ Sbjct: 493 EDKDGDRAVHHAAFGDEGAVIEVLHRGSADLNARNKRRQTPLHIAVNKGHLQVVKTLLDF 552 Query: 552 G 554 G Sbjct: 553 G 553 Score = 56.2 bits (134), Expect = 6e-08 Identities = 45/159 (28%), Positives = 63/159 (39%), Gaps = 36/159 (22%) Frame = +3 Query: 186 DLKLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXX 365 D +H AA GD AV + LN+R++ +TPLH+A GH+ VVK L Sbjct: 498 DRAVHHAA-FGDEGAVIEVLHRGSADLNARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHP 556 Query: 366 XXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGF------------------- 488 +H A K +++ LL +GA V N GF Sbjct: 557 SLQDSEGDTPLHDAISKKRDDILAVLLEAGADVTITNNNGFNALHHAALRGNPSAMRVLL 616 Query: 489 -----------------TALHFAAQNSHLELVKYLVRRG 554 TALH AA N+H+E+ + LV +G Sbjct: 617 SKLPRPWIVDEKKDDGYTALHLAALNNHVEVAELLVHQG 655 Score = 47.0 bits (110), Expect = 4e-05 Identities = 33/119 (27%), Positives = 56/119 (47%), Gaps = 3/119 (2%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDS--DPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKH-KXXX 365 LH AA G+ +A+ L P ++ + T LHLAA HV+V + L Sbjct: 600 LHHAALRGNPSAMRVLLSKLPRPWIVDEKKDDGYTALHLAALNNHVEVAELLVHQGNANL 659 Query: 366 XXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYL 542 +H A ++ H ++VR L+ +GA + +++ G T LH A ++ L ++ L Sbjct: 660 DIQNVNQQTALHLAVERQHTQIVRLLVRAGAKLDIQDKDGDTPLHEALRHHTLSQLRQL 718 Score = 39.3 bits (90), Expect = 0.008 Identities = 20/57 (35%), Positives = 32/57 (56%), Gaps = 1/57 (1%) Frame = +3 Query: 396 IHFASQKGHLEVVRELLASG-ASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 +H A+ H+EV L+ G A++ +N TALH A + H ++V+ LVR G + Sbjct: 636 LHLAALNNHVEVAELLVHQGNANLDIQNVNQQTALHLAVERQHTQIVRLLVRAGAKL 692 Score = 38.1 bits (87), Expect = 0.018 Identities = 24/86 (27%), Positives = 40/86 (46%) Frame = +3 Query: 306 AAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKG 485 AA G V V+ L K + ASQ GH+++++ LL V+A+++ G Sbjct: 438 AAANGDVAKVEDLLKRPDVDVNGQCAGHTAMQAASQNGHVDILKLLLKQNVDVEAEDKDG 497 Query: 486 FTALHFAAQNSHLELVKYLVRRGVDI 563 A+H AA +++ L R D+ Sbjct: 498 DRAVHHAAFGDEGAVIEVLHRGSADL 523
>BARD1_RAT (Q9QZH2) BRCA1-associated RING domain protein 1 (BARD-1)| Length = 768 Score = 57.4 bits (137), Expect = 3e-08 Identities = 34/96 (35%), Positives = 51/96 (53%), Gaps = 2/96 (2%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDS--DPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXX 368 LH A+ GD ++VE L + DP N +D TPLH A GH+ +V+ L +H Sbjct: 422 LHIASIKGDISSVEYLLQNGNDP---NVKDHAGWTPLHEACSHGHLKIVELLLQHNALVN 478 Query: 369 XXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKN 476 +H A++ GH+++V+ LL+ GAS A N Sbjct: 479 TTGYHNDSPLHDAAKNGHIDIVKVLLSHGASRNAVN 514 Score = 48.5 bits (114), Expect = 1e-05 Identities = 29/102 (28%), Positives = 46/102 (45%) Frame = +3 Query: 249 SDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLE 428 S + R+ T LH+A+ G + V+ L ++ +H A GHL+ Sbjct: 406 SSGIPARKRNHRGETLLHIASIKGDISSVEYLLQNGNDPNVKDHAGWTPLHEACSHGHLK 465 Query: 429 VVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 +V LL A V + LH AA+N H+++VK L+ G Sbjct: 466 IVELLLQHNALVNTTGYHNDSPLHDAAKNGHIDIVKVLLSHG 507 Score = 41.6 bits (96), Expect = 0.002 Identities = 20/58 (34%), Positives = 32/58 (55%) Frame = +3 Query: 396 IHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDITT 569 +H AS KG + V LL +G K+ G+T LH A + HL++V+ L++ + T Sbjct: 422 LHIASIKGDISSVEYLLQNGNDPNVKDHAGWTPLHEACSHGHLKIVELLLQHNALVNT 479 Score = 32.0 bits (71), Expect = 1.3 Identities = 14/39 (35%), Positives = 23/39 (58%) Frame = +3 Query: 444 LASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVD 560 L+SG + +N +G T LH A+ + V+YL++ G D Sbjct: 405 LSSGIPARKRNHRGETLLHIASIKGDISSVEYLLQNGND 443
>FANK1_HUMAN (Q8TC84) Fibronectin type 3 and ankyrin repeat domains protein 1| Length = 345 Score = 57.4 bits (137), Expect = 3e-08 Identities = 32/123 (26%), Positives = 60/123 (48%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH+A D + + + ++ ++ T L +AA G+ +VK L + Sbjct: 114 LHRAVSVNDEDLLVRILQGGRVKVDVPNKFGFTALMVAAQKGYTRLVKILVSNGTDVNLK 173 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 + A GHL+VV+ L GAS +A++ G TALH+AA H +++++++ G Sbjct: 174 NGSGKDSLMLACYAGHLDVVKYLRRHGASWQARDLGGCTALHWAADGGHCSVIEWMIKDG 233 Query: 555 VDI 563 ++ Sbjct: 234 CEV 236 Score = 52.0 bits (123), Expect = 1e-06 Identities = 42/154 (27%), Positives = 64/154 (41%), Gaps = 35/154 (22%) Frame = +3 Query: 204 AARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXX 383 AA+ G V+ L S+ +N ++ + L LA +AGH+DVVK L +H Sbjct: 151 AAQKGYTRLVKILV-SNGTDVNLKNGSGKDSLMLACYAGHLDVVKYLRRHGASWQARDLG 209 Query: 384 XXXXIHFASQKGHLEVVRE-----------------------------------LLASGA 458 +H+A+ GH V+ L+ +GA Sbjct: 210 GCTALHWAADGGHCSVIEWMIKDGCEVDVVDTGSGWTPLMRVSAVSGNQRVASLLIDAGA 269 Query: 459 SVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVD 560 +V K+R G T L A N+H ELV+ L+ +G D Sbjct: 270 NVNVKDRNGKTPLMVAVLNNHEELVQLLLDKGAD 303
>TRPA1_RAT (Q6RI86) Transient receptor potential cation channel subfamily A| member 1 (Ankyrin-like with transmembrane domains protein 1) Length = 1125 Score = 57.0 bits (136), Expect = 4e-08 Identities = 43/126 (34%), Positives = 58/126 (46%), Gaps = 3/126 (2%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCD--SDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXX 368 LH AA G + L SD LN D TPLHLAA GH VV+ L K K Sbjct: 451 LHFAASYGRINTCQRLLQDISDTRLLNEGDLHGMTPLHLAAKNGHDKVVQLLLK-KGALF 509 Query: 369 XXXXXXXXXIHFASQKGHLEVVRELLASGASVKAK-NRKGFTALHFAAQNSHLELVKYLV 545 +H AS G+ + ++ +L + + + +G TALHFAA+ H + V L+ Sbjct: 510 LSDHNGWTALHHASMGGYTQTMKVILDTNLKCTDRLDEEGNTALHFAAREGHAKAVAMLL 569 Query: 546 RRGVDI 563 DI Sbjct: 570 SYNADI 575 Score = 48.9 bits (115), Expect = 1e-05 Identities = 38/139 (27%), Positives = 64/139 (46%), Gaps = 11/139 (7%) Frame = +3 Query: 186 DLKLHKAARSGDAAAVESLCD-------SDPLALNSRDRLSRTPLHLAAWAGHVDVVKCL 344 D +H+AA SG +E + S +N + +PLHLA +G +D++K Sbjct: 200 DYPVHQAAFSGAKRCMELILAYGEKTGYSREAHINFVNHKKASPLHLAVQSGDLDMIKMC 259 Query: 345 CKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLAS--GAS--VKAKNRKGFTALHFAAQ 512 +HFA+ +G ++V+ +++S G+S V A + T LH A+ Sbjct: 260 LDSGAHIDMMENAKCMALHFAATQGATDIVKLMISSYTGSSDIVNAVDGNQETLLHRASL 319 Query: 513 NSHLELVKYLVRRGVDITT 569 H +L YL+ G DI + Sbjct: 320 FDHHDLADYLISVGADINS 338 Score = 47.0 bits (110), Expect = 4e-05 Identities = 33/127 (25%), Positives = 63/127 (49%), Gaps = 3/127 (2%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH A R G +V +L + ++++S+ + ++PLH AA G ++ + L + Sbjct: 418 LHYACRQGAPVSVNNLLRFN-VSVHSKSKDKKSPLHFAASYGRINTCQRLLQDISDTRLL 476 Query: 375 XXXXXXX---IHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLV 545 +H A++ GH +VV+ LL GA + + G+TALH A+ + + +K ++ Sbjct: 477 NEGDLHGMTPLHLAAKNGHDKVVQLLLKKGA-LFLSDHNGWTALHHASMGGYTQTMKVIL 535 Query: 546 RRGVDIT 566 + T Sbjct: 536 DTNLKCT 542 Score = 42.4 bits (98), Expect = 0.001 Identities = 26/91 (28%), Positives = 40/91 (43%), Gaps = 3/91 (3%) Frame = +3 Query: 291 TPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKA 470 TPLH A G V L + +HFA+ G + + LL + + Sbjct: 416 TPLHYACRQGAPVSVNNLLRFNVSVHSKSKDKKSPLHFAASYGRINTCQRLLQDISDTRL 475 Query: 471 KNR---KGFTALHFAAQNSHLELVKYLVRRG 554 N G T LH AA+N H ++V+ L+++G Sbjct: 476 LNEGDLHGMTPLHLAAKNGHDKVVQLLLKKG 506 Score = 42.0 bits (97), Expect = 0.001 Identities = 33/125 (26%), Positives = 51/125 (40%), Gaps = 2/125 (1%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPL-ALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXX 371 LH AA G ++ + + ALN D TPLH AA V+ VK L Sbjct: 68 LHHAAAEGQVELMQLIINGSSCEALNVMDDYGNTPLHWAAEKNQVESVKFLLSQGANPNL 127 Query: 372 XXXXXXXXIHFASQKGHLEVVRELLASGA-SVKAKNRKGFTALHFAAQNSHLELVKYLVR 548 +H A Q + EV++ L A ++ + G TAL + E ++ L+ Sbjct: 128 RNRNMMAPLHIAVQGMYNEVIKVLTEHKATNINLEGENGNTALMSTCAKDNSEALQILLE 187 Query: 549 RGVDI 563 +G + Sbjct: 188 KGAKL 192 Score = 35.8 bits (81), Expect = 0.088 Identities = 30/106 (28%), Positives = 45/106 (42%), Gaps = 1/106 (0%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXX-XXX 371 LH AA +V+ L S N R+R PLH+A + +V+K L +HK Sbjct: 103 LHWAAEKNQVESVKFLL-SQGANPNLRNRNMMAPLHIAVQGMYNEVIKVLTEHKATNINL 161 Query: 372 XXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAA 509 + K + E ++ LL GA + N+ G +H AA Sbjct: 162 EGENGNTALMSTCAKDNSEALQILLEKGAKLCKSNKWGDYPVHQAA 207
>TRPA1_MOUSE (Q8BLA8) Transient receptor potential cation channel subfamily A| member 1 (Ankyrin-like with transmembrane domains protein 1) Length = 1125 Score = 57.0 bits (136), Expect = 4e-08 Identities = 43/126 (34%), Positives = 58/126 (46%), Gaps = 3/126 (2%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCD--SDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXX 368 LH AA G + L SD LN D TPLHLAA GH VV+ L K K Sbjct: 451 LHFAASYGRINTCQRLLQDISDTRLLNEGDLHGMTPLHLAAKNGHDKVVQLLLK-KGALF 509 Query: 369 XXXXXXXXXIHFASQKGHLEVVRELLASGASVKAK-NRKGFTALHFAAQNSHLELVKYLV 545 +H AS G+ + ++ +L + + + +G TALHFAA+ H + V L+ Sbjct: 510 LSDHNGWTALHHASMGGYTQTMKVILDTNLKCTDRLDEEGNTALHFAAREGHAKAVAMLL 569 Query: 546 RRGVDI 563 DI Sbjct: 570 SYNADI 575 Score = 50.4 bits (119), Expect = 3e-06 Identities = 38/139 (27%), Positives = 66/139 (47%), Gaps = 11/139 (7%) Frame = +3 Query: 186 DLKLHKAARSGDAAAVESLCD-------SDPLALNSRDRLSRTPLHLAAWAGHVDVVKCL 344 D +H+AA SG +E + S +N + +PLHLA +G +D++K Sbjct: 200 DYPVHQAAFSGAKKCMELILAYGEKNGYSRETHINFVNHKKASPLHLAVQSGDLDMIKMC 259 Query: 345 CKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLAS--GAS--VKAKNRKGFTALHFAAQ 512 + +HFA+ +G ++V+ +++S G+S V A + T LH A+ Sbjct: 260 LDNGAHIDMMENAKCMALHFAATQGATDIVKLMISSYTGSSDIVNAVDGNQETLLHRASL 319 Query: 513 NSHLELVKYLVRRGVDITT 569 H +L +YL+ G DI + Sbjct: 320 FDHHDLAEYLISVGADINS 338 Score = 47.4 bits (111), Expect = 3e-05 Identities = 33/127 (25%), Positives = 63/127 (49%), Gaps = 3/127 (2%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH A R G +V +L + ++++S+ + ++PLH AA G ++ + L + Sbjct: 418 LHYACRQGVPVSVNNLLGFN-VSIHSKSKDKKSPLHFAASYGRINTCQRLLQDISDTRLL 476 Query: 375 XXXXXXX---IHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLV 545 +H A++ GH +VV+ LL GA + + G+TALH A+ + + +K ++ Sbjct: 477 NEGDLHGMTPLHLAAKNGHDKVVQLLLKKGA-LFLSDHNGWTALHHASMGGYTQTMKVIL 535 Query: 546 RRGVDIT 566 + T Sbjct: 536 DTNLKCT 542 Score = 40.4 bits (93), Expect = 0.004 Identities = 24/85 (28%), Positives = 41/85 (48%), Gaps = 2/85 (2%) Frame = +3 Query: 294 PLHLAAWAGHVDVVKCLCKHKX--XXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVK 467 PLH AA G V++++ + +H A++K +E V+ LL+ GA+ Sbjct: 67 PLHHAAAEGQVELMELIINGSSCEVLNIMDGYGNTPLHCAAEKNQVESVKFLLSQGANPN 126 Query: 468 AKNRKGFTALHFAAQNSHLELVKYL 542 +NR + LH A + E++K L Sbjct: 127 LRNRNMMSPLHIAVHGMYNEVIKVL 151 Score = 36.6 bits (83), Expect = 0.051 Identities = 31/121 (25%), Positives = 53/121 (43%), Gaps = 1/121 (0%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXX-XXX 371 LH AA +V+ L S N R+R +PLH+A + +V+K L +HK Sbjct: 103 LHCAAEKNQVESVKFLL-SQGANPNLRNRNMMSPLHIAVHGMYNEVIKVLTEHKATNINL 161 Query: 372 XXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRR 551 + K + E ++ LL GA + N+ G +H AA + + ++ ++ Sbjct: 162 EGENGNTALMSTCAKDNSEALQILLEKGAKLCKSNKWGDYPVHQAAFSGAKKCMELILAY 221 Query: 552 G 554 G Sbjct: 222 G 222
>TRPA1_HUMAN (O75762) Transient receptor potential cation channel subfamily A| member 1 (Ankyrin-like with transmembrane domains protein 1) (Transformation sensitive-protein p120) Length = 1119 Score = 57.0 bits (136), Expect = 4e-08 Identities = 43/126 (34%), Positives = 57/126 (45%), Gaps = 3/126 (2%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCD--SDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXX 368 LH AA G + L SD LN D TPLHLAA GH VV+ L K K Sbjct: 450 LHFAASYGRINTCQRLLQDISDTRLLNEGDLHGMTPLHLAAKNGHDKVVQLLLK-KGALF 508 Query: 369 XXXXXXXXXIHFASQKGHLEVVRELLASGASVKAK-NRKGFTALHFAAQNSHLELVKYLV 545 +H AS G+ + ++ +L + + + G TALHFAA+ H + V L+ Sbjct: 509 LSDHNGWTALHHASMGGYTQTMKVILDTNLKCTDRLDEDGNTALHFAAREGHAKAVALLL 568 Query: 546 RRGVDI 563 DI Sbjct: 569 SHNADI 574 Score = 49.7 bits (117), Expect = 6e-06 Identities = 40/134 (29%), Positives = 60/134 (44%), Gaps = 11/134 (8%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCD-------SDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKH 353 +H+AA SG +E + S L +N + TPLHLA G ++++K + Sbjct: 202 IHQAAFSGSKECMEIILRFGEEHGYSRQLHINFMNNGKATPLHLAVQNGDLEMIKMCLDN 261 Query: 354 KXXXXXXXXXXXXXIHFASQKGHLEVVRELLAS-GASVKAKNRKGF---TALHFAAQNSH 521 IHFA+ +G E+V+ +++S SV N T LH A+ H Sbjct: 262 GAQIDPVEKGRCTAIHFAATQGATEIVKLMISSYSGSVDIVNTTDGCHETMLHRASLFDH 321 Query: 522 LELVKYLVRRGVDI 563 EL YL+ G DI Sbjct: 322 HELADYLISVGADI 335 Score = 48.1 bits (113), Expect = 2e-05 Identities = 33/127 (25%), Positives = 63/127 (49%), Gaps = 3/127 (2%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH A R G +V +L + ++++S+ + ++PLH AA G ++ + L + Sbjct: 417 LHYACRQGGPGSVNNLLGFN-VSIHSKSKDKKSPLHFAASYGRINTCQRLLQDISDTRLL 475 Query: 375 XXXXXXX---IHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLV 545 +H A++ GH +VV+ LL GA + + G+TALH A+ + + +K ++ Sbjct: 476 NEGDLHGMTPLHLAAKNGHDKVVQLLLKKGA-LFLSDHNGWTALHHASMGGYTQTMKVIL 534 Query: 546 RRGVDIT 566 + T Sbjct: 535 DTNLKCT 541 Score = 40.8 bits (94), Expect = 0.003 Identities = 23/92 (25%), Positives = 43/92 (46%), Gaps = 8/92 (8%) Frame = +3 Query: 294 PLHLAAWAGHVDVVKCLCK--------HKXXXXXXXXXXXXXIHFASQKGHLEVVRELLA 449 P+H AA++G + ++ + + + +H A Q G LE+++ L Sbjct: 201 PIHQAAFSGSKECMEIILRFGEEHGYSRQLHINFMNNGKATPLHLAVQNGDLEMIKMCLD 260 Query: 450 SGASVKAKNRKGFTALHFAAQNSHLELVKYLV 545 +GA + + TA+HFAA E+VK ++ Sbjct: 261 NGAQIDPVEKGRCTAIHFAATQGATEIVKLMI 292
>CSKI2_XENLA (Q6DD51) Caskin-2| Length = 1205 Score = 57.0 bits (136), Expect = 4e-08 Identities = 40/131 (30%), Positives = 63/131 (48%), Gaps = 8/131 (6%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AA G V L + ++N+ + PLHLAA GH +V + L +H+ Sbjct: 86 LHYAAWQGQPEPVRLLLRASA-SVNAASHDGQIPLHLAAQYGHYEVSETLLQHQSNPCHV 144 Query: 375 XXXXXXXIHFASQKGHLEVVRELLAS--------GASVKAKNRKGFTALHFAAQNSHLEL 530 + A + G ++VV+ LL S G S + T LH AA+N HLE+ Sbjct: 145 NKGKKTPLDLACEFGRVKVVQLLLNSHLCVSLLEGTSKDPTDPNFTTPLHLAAKNGHLEV 204 Query: 531 VKYLVRRGVDI 563 ++ L++ G++I Sbjct: 205 IRLLLKLGIEI 215 Score = 56.6 bits (135), Expect = 5e-08 Identities = 45/135 (33%), Positives = 61/135 (45%), Gaps = 10/135 (7%) Frame = +3 Query: 189 LKLHKAARSGDAAAVESLCD--SDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXX 362 + LH AA+ G E+L S+P +N +TPL LA G V VV+ L Sbjct: 117 IPLHLAAQYGHYEVSETLLQHQSNPCHVNKG---KKTPLDLACEFGRVKVVQLLLNSHLC 173 Query: 363 XXXXXXXX--------XXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNS 518 +H A++ GHLEV+R LL G + + G TALH AA Sbjct: 174 VSLLEGTSKDPTDPNFTTPLHLAAKNGHLEVIRLLLKLGIEINKVTKMG-TALHEAALCG 232 Query: 519 HLELVKYLVRRGVDI 563 E+VK L+ GVD+ Sbjct: 233 KTEVVKLLIENGVDV 247 Score = 52.0 bits (123), Expect = 1e-06 Identities = 38/131 (29%), Positives = 63/131 (48%), Gaps = 12/131 (9%) Frame = +3 Query: 192 KLHKAARSGDAAAVES------------LCDSDPLALNSRDRLSRTPLHLAAWAGHVDVV 335 +L +A +SGD AV+ L + L +N +D + LH AA +G+ +++ Sbjct: 6 ELIQAVKSGDVGAVQKFLAKFRTPKSKLLGSTKRLNVNHQDADGFSALHHAALSGNSELL 65 Query: 336 KCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQN 515 L + + +H+A+ +G E VR LL + ASV A + G LH AAQ Sbjct: 66 LLLLEMQASVDIKDGNGMRPLHYAAWQGQPEPVRLLLRASASVNAASHDGQIPLHLAAQY 125 Query: 516 SHLELVKYLVR 548 H E+ + L++ Sbjct: 126 GHYEVSETLLQ 136 Score = 42.4 bits (98), Expect = 0.001 Identities = 31/94 (32%), Positives = 45/94 (47%), Gaps = 3/94 (3%) Frame = +3 Query: 291 TPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKA 470 TPLHLAA GH++V++ L K +H A+ G EVV+ L+ +G V Sbjct: 191 TPLHLAAKNGHLEVIRLLLK-LGIEINKVTKMGTALHEAALCGKTEVVKLLIENGVDVNI 249 Query: 471 KNRKGFTALHFAAQ--NSHLEL-VKYLVRRGVDI 563 +N TAL Q +H + +K L+R I Sbjct: 250 RNTYNQTALDIVNQFTTTHASIDIKQLLREASGI 283 Score = 34.7 bits (78), Expect = 0.20 Identities = 19/56 (33%), Positives = 29/56 (51%) Frame = +3 Query: 396 IHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 +H A+ G+ E++ LL ASV K+ G LH+AA E V+ L+R + Sbjct: 53 LHHAALSGNSELLLLLLEMQASVDIKDGNGMRPLHYAAWQGQPEPVRLLLRASASV 108
>FANK1_BOVIN (Q6B858) Fibronectin type 3 and ankyrin repeat domains protein 1| (GV14) Length = 345 Score = 57.0 bits (136), Expect = 4e-08 Identities = 32/123 (26%), Positives = 57/123 (46%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH+A D + + + ++ ++ T L +AA G+ +VK L H Sbjct: 114 LHRAVNVNDEDLLVRILQGGNVKVDVPNKFGFTALMVAAQRGYTRLVKILISHGTDVNLQ 173 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 + A GHL+VV+ L GAS ++ G TALH+AA H ++++++ G Sbjct: 174 NGSGKDSLMLACYAGHLDVVKYLRRHGASWDTRDMGGCTALHWAADGGHCNVIEWMIGDG 233 Query: 555 VDI 563 ++ Sbjct: 234 CEV 236 Score = 50.1 bits (118), Expect = 4e-06 Identities = 43/154 (27%), Positives = 62/154 (40%), Gaps = 35/154 (22%) Frame = +3 Query: 204 AARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXX 383 AA+ G V+ L S +N ++ + L LA +AGH+DVVK L +H Sbjct: 151 AAQRGYTRLVKILI-SHGTDVNLQNGSGKDSLMLACYAGHLDVVKYLRRHGASWDTRDMG 209 Query: 384 XXXXIHFASQKGHL-----------------------------------EVVRELLASGA 458 +H+A+ GH EV L+ +GA Sbjct: 210 GCTALHWAADGGHCNVIEWMIGDGCEVDAVDAGSRWTPLMRVSAVSGNQEVASLLIDAGA 269 Query: 459 SVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVD 560 V K++ G T L A N+H ELV+ L+ RG D Sbjct: 270 DVNVKDKDGKTPLMVAVLNNHEELVQLLLDRGAD 303 Score = 40.4 bits (93), Expect = 0.004 Identities = 20/55 (36%), Positives = 31/55 (56%) Frame = +3 Query: 405 ASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDITT 569 A+Q+G+ +V+ L++ G V +N G +L A HL++VKYL R G T Sbjct: 151 AAQRGYTRLVKILISHGTDVNLQNGSGKDSLMLACYAGHLDVVKYLRRHGASWDT 205
>AKR1_SCHPO (Q09701) Palmitoyltransferase akr1 (EC 2.3.1.-) (Ankyrin| repeat-containing protein akr1) Length = 642 Score = 56.6 bits (135), Expect = 5e-08 Identities = 35/124 (28%), Positives = 59/124 (47%), Gaps = 1/124 (0%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 L AA G+ V++L S+ + +N+ D T LH AA + + K L +H Sbjct: 4 LFLAASQGELDTVKNLISSEKIDVNATDEGGATALHWAALNQQIPICKFLLEHGADVNAI 63 Query: 375 XXXXXXX-IHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRR 551 IH+A+++G ++ V L+ GA K+++GF LH A + LV YL+ Sbjct: 64 GGDLQAAPIHWAAKRGSVKTVHYLVQHGADPLLKDKQGFNCLHLAVHAASPLLVVYLLHL 123 Query: 552 GVDI 563 + + Sbjct: 124 DISV 127 Score = 30.8 bits (68), Expect = 2.8 Identities = 20/87 (22%), Positives = 38/87 (43%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH A + V L D ++++ RD TPL A++ G+ + CL + Sbjct: 105 LHLAVHAASPLLVVYLLHLD-ISVDLRDDQQHTPLMWASYHGNEPITNCLLRWGADVLAT 163 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASG 455 +H++ G+L+ ++ +L G Sbjct: 164 DEDKMTPLHWSIVGGNLKCMKLILKEG 190
>ANKR5_HUMAN (Q9NU02) Ankyrin repeat domain-containing protein 5| Length = 776 Score = 56.6 bits (135), Expect = 5e-08 Identities = 34/115 (29%), Positives = 60/115 (52%) Frame = +3 Query: 210 RSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXX 389 ++GD A+++ +S + ++ +D +TPL A +G++DVVK L + Sbjct: 501 KAGDLASLKKAFESG-IPVDMKDNYYKTPLMTACASGNIDVVKFLLEKGANVNATDNFLW 559 Query: 390 XXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 +HFA G ++V L+ SGA + A + T L+ A ++ L+ VKYL+ G Sbjct: 560 TPLHFACHAGQQDIVELLVESGALIDAASINNSTPLNRAIESCRLDTVKYLLDIG 614 Score = 48.1 bits (113), Expect = 2e-05 Identities = 33/121 (27%), Positives = 56/121 (46%), Gaps = 6/121 (4%) Frame = +3 Query: 219 DAAAVESLC------DSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXX 380 DA V+ +C ++P A+NS RT L A+ G V++V+ + + Sbjct: 159 DAHDVKDVCLTFLEKGANPNAINSST--GRTALMEASREGVVEIVRGILERGGEVNAFDN 216 Query: 381 XXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVD 560 HFA++ G ++++ L A V + G T LH+AA + KY+ +RG D Sbjct: 217 DRHHAAHFAAKGGFFDILKLLFAYNGDVGLISINGNTPLHYAAMGGFADCCKYIAQRGCD 276 Query: 561 I 563 + Sbjct: 277 L 277 Score = 46.2 bits (108), Expect = 6e-05 Identities = 33/122 (27%), Positives = 56/122 (45%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 L A SG+ V+ L + +N+ D TPLH A AG D+V+ L + Sbjct: 529 LMTACASGNIDVVKFLLEKGA-NVNATDNFLWTPLHFACHAGQQDIVELLVESGALIDAA 587 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 ++ A + L+ V+ LL GA + +NRKG +A+ A + ++ L++ Sbjct: 588 SINNSTPLNRAIESCRLDTVKYLLDIGAKFQLENRKGHSAMDVAKAYADYRIID-LIKEK 646 Query: 555 VD 560 +D Sbjct: 647 LD 648 Score = 30.4 bits (67), Expect = 3.7 Identities = 21/94 (22%), Positives = 37/94 (39%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 L +A+R G V + + +N+ D H AA G D++K L + Sbjct: 189 LMEASREGVVEIVRGILERGG-EVNAFDNDRHHAAHFAAKGGFFDILKLLFAYNGDVGLI 247 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKN 476 +H+A+ G + + + G +K KN Sbjct: 248 SINGNTPLHYAAMGGFADCCKYIAQRGCDLKWKN 281
>ANR11_HUMAN (Q6UB99) Ankyrin repeat domain-containing protein 11 (Ankyrin| repeat-containing cofactor 1) Length = 2664 Score = 56.6 bits (135), Expect = 5e-08 Identities = 33/97 (34%), Positives = 46/97 (47%) Frame = +3 Query: 264 LNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVREL 443 +N R+ T LH AA G +K L +H A +G+ +V ++L Sbjct: 162 VNKRNERGETRLHRAAIRGDARRIKELISEGADVNVKDFAGWTALHEACNRGYYDVAKQL 221 Query: 444 LASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 LA+GA V K T LH AA N H ++VK L+R G Sbjct: 222 LAAGAEVNTKGLDDDTPLHDAANNGHYKVVKLLLRYG 258 Score = 53.9 bits (128), Expect = 3e-07 Identities = 37/116 (31%), Positives = 55/116 (47%) Frame = +3 Query: 186 DLKLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXX 365 + +LH+AA GDA ++ L S+ +N +D T LH A G+ DV K L Sbjct: 170 ETRLHRAAIRGDARRIKELI-SEGADVNVKDFAGWTALHEACNRGYYDVAKQLLAAGAEV 228 Query: 366 XXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELV 533 +H A+ GH +VV+ LL G + + NRKG T L A + + L+ Sbjct: 229 NTKGLDDDTPLHDAANNGHYKVVKLLLRYGGNPQQSNRKGETPLKVANSPTMVNLL 284 Score = 43.5 bits (101), Expect = 4e-04 Identities = 19/58 (32%), Positives = 34/58 (58%) Frame = +3 Query: 396 IHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDITT 569 +H A+ +G ++EL++ GA V K+ G+TALH A + ++ K L+ G ++ T Sbjct: 173 LHRAAIRGDARRIKELISEGADVNVKDFAGWTALHEACNRGYYDVAKQLLAAGAEVNT 230
>ANKS1_MOUSE (P59672) Ankyrin repeat and SAM domain-containing protein 1A| Length = 1149 Score = 56.2 bits (134), Expect = 6e-08 Identities = 40/125 (32%), Positives = 52/125 (41%), Gaps = 24/125 (19%) Frame = +3 Query: 264 LNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVREL 443 +N D TPLH AA GH DVV+ L ++ +H A+ KG ++VR L Sbjct: 68 VNCVDSTGYTPLHHAALNGHRDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIVRLL 127 Query: 444 LASGAS------------------------VKAKNRKGFTALHFAAQNSHLELVKYLVRR 551 + G S + AKN TALH AAQ H E+VK L+ Sbjct: 128 IQQGPSHTRVNEQNALEIRELKKYGPFDPYINAKNNDNETALHCAAQYGHTEVVKALLEE 187 Query: 552 GVDIT 566 D T Sbjct: 188 LTDPT 192 Score = 55.5 bits (132), Expect = 1e-07 Identities = 41/145 (28%), Positives = 62/145 (42%), Gaps = 23/145 (15%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLA-----------------------LNSRDRLSRTPLHL 305 LH AA GDA V L P +N+++ + T LH Sbjct: 112 LHLAAWKGDAQIVRLLIQQGPSHTRVNEQNALEIRELKKYGPFDPYINAKNNDNETALHC 171 Query: 306 AAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKG 485 AA GH +VVK L + + A+ G LEVV+ LL + ++ + + + Sbjct: 172 AAQYGHTEVVKALLEELTDPTMRNNKFETPLDLAALYGRLEVVKLLLGAHPNLLSCSTRK 231 Query: 486 FTALHFAAQNSHLELVKYLVRRGVD 560 T LH AA+N H +V+ L+ G+D Sbjct: 232 HTPLHLAARNGHKAVVQVLLDAGMD 256 Score = 54.7 bits (130), Expect = 2e-07 Identities = 40/125 (32%), Positives = 62/125 (49%), Gaps = 2/125 (1%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCD--SDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXX 368 LH AA+ G V++L + +DP N++ TPL LAA G ++VVK L Sbjct: 169 LHCAAQYGHTEVVKALLEELTDPTMRNNK---FETPLDLAALYGRLEVVKLLLGAHPNLL 225 Query: 369 XXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVR 548 +H A++ GH VV+ LL +G + G +ALH AA ++V+ L+ Sbjct: 226 SCSTRKHTPLHLAARNGHKAVVQVLLDAGMDSNYQTEMG-SALHEAALFGKTDVVQILLA 284 Query: 549 RGVDI 563 G+D+ Sbjct: 285 AGIDV 289 Score = 45.4 bits (106), Expect = 1e-04 Identities = 36/101 (35%), Positives = 47/101 (46%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 L AA G V+ L + P L+ R TPLHLAA GH VV+ L Sbjct: 202 LDLAALYGRLEVVKLLLGAHPNLLSCSTR-KHTPLHLAARNGHKAVVQVLLD-AGMDSNY 259 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTAL 497 +H A+ G +VV+ LLA+G V K+ +G TAL Sbjct: 260 QTEMGSALHEAALFGKTDVVQILLAAGIDVNIKDNRGLTAL 300 Score = 30.0 bits (66), Expect = 4.8 Identities = 13/32 (40%), Positives = 20/32 (62%) Frame = +3 Query: 453 GASVKAKNRKGFTALHFAAQNSHLELVKYLVR 548 G +V + G+T LH AA N H ++V+ L+R Sbjct: 65 GPNVNCVDSTGYTPLHHAALNGHRDVVEVLLR 96
>CSKI2_MOUSE (Q8VHK1) Caskin-2| Length = 1201 Score = 55.8 bits (133), Expect = 8e-08 Identities = 42/135 (31%), Positives = 63/135 (46%), Gaps = 10/135 (7%) Frame = +3 Query: 189 LKLHKAARSGDAAAVESLCD--SDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXX 362 + LH AA+ G E L S+P +N +L +TPL LA G + V + L Sbjct: 117 IPLHLAAQYGHYEVSEMLLQHQSNPCLVN---KLKKTPLDLACEFGRLKVAQLLLNSHLC 173 Query: 363 XXXXXXXX--------XXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNS 518 +H A++ GH EV+R+LL +G + + + G TALH AA Sbjct: 174 VALLEGEAKDPCDPNYTTPLHLAAKNGHREVIRQLLKAGIEINRQTKTG-TALHEAALYG 232 Query: 519 HLELVKYLVRRGVDI 563 E+V+ L+ GVD+ Sbjct: 233 KTEVVRLLLEGGVDV 247 Score = 52.4 bits (124), Expect = 9e-07 Identities = 33/109 (30%), Positives = 55/109 (50%) Frame = +3 Query: 222 AAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIH 401 AA + L + L +N +D + LH AA G ++++ L + + +H Sbjct: 28 AAKTKLLGSTKRLNINYQDADGFSALHHAALGGSLELIALLLEAQATVDIKDSNGMRPLH 87 Query: 402 FASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVR 548 +A+ +G LE VR LL + A+V A + G LH AAQ H E+ + L++ Sbjct: 88 YAAWQGRLEPVRLLLRASAAVNAASLDGQIPLHLAAQYGHYEVSEMLLQ 136 Score = 52.0 bits (123), Expect = 1e-06 Identities = 39/131 (29%), Positives = 61/131 (46%), Gaps = 8/131 (6%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AA G V L + A+N+ + PLHLAA GH +V + L +H+ Sbjct: 86 LHYAAWQGRLEPVRLLLRASA-AVNAASLDGQIPLHLAAQYGHYEVSEMLLQHQSNPCLV 144 Query: 375 XXXXXXXIHFASQKGHLEVVRELLAS--------GASVKAKNRKGFTALHFAAQNSHLEL 530 + A + G L+V + LL S G + + T LH AA+N H E+ Sbjct: 145 NKLKKTPLDLACEFGRLKVAQLLLNSHLCVALLEGEAKDPCDPNYTTPLHLAAKNGHREV 204 Query: 531 VKYLVRRGVDI 563 ++ L++ G++I Sbjct: 205 IRQLLKAGIEI 215 Score = 48.1 bits (113), Expect = 2e-05 Identities = 31/117 (26%), Positives = 51/117 (43%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AA G + L ++ ++ +D PLH AAW G ++ V+ L + Sbjct: 53 LHHAALGGSLELIALLLEAQA-TVDIKDSNGMRPLHYAAWQGRLEPVRLLLRASAAVNAA 111 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLV 545 +H A+Q GH EV LL ++ N+ T L A + L++ + L+ Sbjct: 112 SLDGQIPLHLAAQYGHYEVSEMLLQHQSNPCLVNKLKKTPLDLACEFGRLKVAQLLL 168 Score = 41.6 bits (96), Expect = 0.002 Identities = 28/74 (37%), Positives = 34/74 (45%) Frame = +3 Query: 291 TPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKA 470 TPLHLAA GH +V++ L K +H A+ G EVVR LL G V Sbjct: 191 TPLHLAAKNGHREVIRQLLK-AGIEINRQTKTGTALHEAALYGKTEVVRLLLEGGVDVNI 249 Query: 471 KNRKGFTALHFAAQ 512 +N TAL Q Sbjct: 250 RNTYNQTALDIVNQ 263
>LCTA_LATMA (Q9XZC0) Alpha-latrocrustotoxin (Alpha-LCT) (Crusta1)| Length = 1395 Score = 55.8 bits (133), Expect = 8e-08 Identities = 35/123 (28%), Positives = 55/123 (44%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH A +SL + +++R + TPLHLAA G+ +VK + Sbjct: 686 LHLAILFKKFDVAQSLLQVRNIDISTRADQAITPLHLAAATGNSQIVKTILNSGAVVDQE 745 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 +H A + E + L+A GA++ AK G T LHFAA + + L+ +G Sbjct: 746 TANGFTALHLAIMNPNTETPQFLIAKGANINAKTNDGSTPLHFAAALGKTNIFQLLMDKG 805 Query: 555 VDI 563 +I Sbjct: 806 ANI 808 Score = 53.5 bits (127), Expect = 4e-07 Identities = 34/123 (27%), Positives = 58/123 (47%), Gaps = 1/123 (0%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AA G + L D + + + +++ P+H A GH+ +VK L + Sbjct: 786 LHFAAALGKTNIFQLLMDKGA-NIKAENLINQMPIHEAVVNGHLAIVKMLIEQDSSLMNA 844 Query: 375 XXXXXXX-IHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRR 551 + A++K + +V L + GA V KN G T LH + N +E+V++L++ Sbjct: 845 KNMRDEYPFYLAAEKRYKDVFNYLESKGADVNEKNNDGNTLLHLFSINGEVEVVQFLIQN 904 Query: 552 GVD 560 G D Sbjct: 905 GAD 907 Score = 51.6 bits (122), Expect = 2e-06 Identities = 31/112 (27%), Positives = 53/112 (47%), Gaps = 1/112 (0%) Frame = +3 Query: 231 VESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFAS 410 VE L D P D TP+ A + V ++ L ++ + A+ Sbjct: 1042 VEYLVDKTPDINKECDTQQSTPVSSAVYGNKVSILNYLIRN-GADPNKKVRGDPPLFIAA 1100 Query: 411 QKGHLEVVRELLASGA-SVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 G ++V+ L+ V +N++ FT LH AA N H+++VKYL+++G D+ Sbjct: 1101 MIGQYDIVKSLVEQHKIDVNTRNKEQFTPLHAAASNDHIDVVKYLIQKGADV 1152 Score = 50.4 bits (119), Expect = 3e-06 Identities = 33/126 (26%), Positives = 57/126 (45%), Gaps = 3/126 (2%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AAR V++L + + +N+++R TPLHL+ + + + Sbjct: 549 LHLAARQDFTIIVKTLMEKRGIDVNAKERAGFTPLHLSITSNSRAARTLINETPAGINIK 608 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAK--NRKGFTALHFAAQNSHLELVKYLV- 545 +H A + +L + L+ S VK + G T LH+A+ +LE VKY Sbjct: 609 SNSGLTPLHLAVLQNNLSAAKVLVKSNKKVKLNEMDNNGMTPLHYASMLGNLEFVKYFTS 668 Query: 546 RRGVDI 563 +G+D+ Sbjct: 669 EQGIDV 674 Score = 48.9 bits (115), Expect = 1e-05 Identities = 29/119 (24%), Positives = 54/119 (45%) Frame = +3 Query: 189 LKLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXX 368 + +H+A +G A V+ L + D +N+++ P +LAA + DV L Sbjct: 817 MPIHEAVVNGHLAIVKMLIEQDSSLMNAKNMRDEYPFYLAAEKRYKDVFNYLESKGADVN 876 Query: 369 XXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLV 545 +H S G +EVV+ L+ +GA + +N++ + A + H +V Y + Sbjct: 877 EKNNDGNTLLHLFSINGEVEVVQFLIQNGADFRLRNKERKSFFDLAVEFGHAGIVGYAI 935 Score = 45.4 bits (106), Expect = 1e-04 Identities = 27/101 (26%), Positives = 46/101 (45%), Gaps = 1/101 (0%) Frame = +3 Query: 264 LNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVREL 443 +N++ TPLH AA G ++ + L IH A GHL +V+ L Sbjct: 775 INAKTNDGSTPLHFAAALGKTNIFQLLMDKGANIKAENLINQMPIHEAVVNGHLAIVKML 834 Query: 444 LASGASV-KAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 + +S+ AKN + + AA+ + ++ YL +G D+ Sbjct: 835 IEQDSSLMNAKNMRDEYPFYLAAEKRYKDVFNYLESKGADV 875 Score = 43.5 bits (101), Expect = 4e-04 Identities = 24/76 (31%), Positives = 36/76 (47%), Gaps = 1/76 (1%) Frame = +3 Query: 294 PLHLAAWAGHVDVVKCLCK-HKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKA 470 PL +AA G D+VK L + HK +H A+ H++VV+ L+ GA V A Sbjct: 1095 PLFIAAMIGQYDIVKSLVEQHKIDVNTRNKEQFTPLHAAASNDHIDVVKYLIQKGADVNA 1154 Query: 471 KNRKGFTALHFAAQNS 518 K + + A + S Sbjct: 1155 KGDENLKPIDLAGEKS 1170 Score = 42.7 bits (99), Expect = 7e-04 Identities = 31/106 (29%), Positives = 48/106 (45%), Gaps = 2/106 (1%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLC-KHKXXXXX 371 +H +A +G+ L + LN D+ TPLH+A+ + D VK L K Sbjct: 481 IHASATAGNDDVARLLLAKNNGLLNVPDKNGYTPLHIASERKNNDFVKFLLEKGADVNVR 540 Query: 372 XXXXXXXXIHFASQKGHLEVVRELLAS-GASVKAKNRKGFTALHFA 506 +H A+++ +V+ L+ G V AK R GFT LH + Sbjct: 541 TFANELTPLHLAARQDFTIIVKTLMEKRGIDVNAKERAGFTPLHLS 586 Score = 38.9 bits (89), Expect = 0.010 Identities = 18/57 (31%), Positives = 35/57 (61%), Gaps = 1/57 (1%) Frame = +3 Query: 396 IHFASQKGHLEVVRELLA-SGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 IH ++ G+ +V R LLA + + ++ G+T LH A++ + + VK+L+ +G D+ Sbjct: 481 IHASATAGNDDVARLLLAKNNGLLNVPDKNGYTPLHIASERKNNDFVKFLLEKGADV 537 Score = 38.1 bits (87), Expect = 0.018 Identities = 22/53 (41%), Positives = 30/53 (56%) Frame = +3 Query: 186 DLKLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCL 344 D L AA G V+SL + + +N+R++ TPLH AA H+DVVK L Sbjct: 1093 DPPLFIAAMIGQYDIVKSLVEQHKIDVNTRNKEQFTPLHAAASNDHIDVVKYL 1145
>FANK1_MOUSE (Q9DAM9) Fibronectin type 3 and ankyrin repeat domains 1 protein| (Germ cell-specific gene 1 protein) (GSG1) Length = 344 Score = 55.8 bits (133), Expect = 8e-08 Identities = 31/122 (25%), Positives = 59/122 (48%) Frame = +3 Query: 198 HKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXX 377 H+A D + + + + ++ ++ T L +AA G+ +VK L + Sbjct: 115 HRAVSVNDEDLLLRILEGGHVMIDVPNKFGFTALMVAAQKGYTRLVKILVSNGTDVNLKN 174 Query: 378 XXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGV 557 + A GHL+VV+ L GAS +A++ G TALH+AA H ++ ++++ G Sbjct: 175 GSGKDSLMLACYAGHLDVVKYLRRHGASWEARDLGGCTALHWAADGGHCSVIDWMIKDGC 234 Query: 558 DI 563 ++ Sbjct: 235 EV 236 Score = 50.1 bits (118), Expect = 4e-06 Identities = 41/156 (26%), Positives = 64/156 (41%), Gaps = 35/156 (22%) Frame = +3 Query: 204 AARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXX 383 AA+ G V+ L S+ +N ++ + L LA +AGH+DVVK L +H Sbjct: 151 AAQKGYTRLVKILV-SNGTDVNLKNGSGKDSLMLACYAGHLDVVKYLRRHGASWEARDLG 209 Query: 384 XXXXIHFASQKGHLEVV-----------------------------------RELLASGA 458 +H+A+ GH V+ L+ +GA Sbjct: 210 GCTALHWAADGGHCSVIDWMIKDGCEVDVVDTGSGWTPLMRVSAVTGSQKVASLLIEAGA 269 Query: 459 SVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDIT 566 V K++ G T L A N+H +LV+ L+ +G D T Sbjct: 270 DVNIKDKDGKTPLMVAVLNNHEQLVQLLLDKGADAT 305
>INVSA_XENLA (Q71S22) Inversin-A| Length = 1007 Score = 55.5 bits (132), Expect = 1e-07 Identities = 31/120 (25%), Positives = 57/120 (47%), Gaps = 1/120 (0%) Frame = +3 Query: 204 AARSGDAAAVESLCDSDP-LALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXX 380 AA G V ++ + DP L +N D+ T LH A+ +G + V+ L +++ Sbjct: 325 AAGKGSDEVVRTMLELDPELEVNRTDKYGGTALHAASLSGQITTVRILLENRVQVDAVDV 384 Query: 381 XXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVD 560 + A + GH EV+ L+ GA V ++ G + LH+AA + + + L+ ++ Sbjct: 385 MKHTALFRACEMGHREVISTLIKGGAKVHLVDKDGRSPLHWAALGGNANVCQILIENNIN 444 Score = 46.6 bits (109), Expect = 5e-05 Identities = 26/115 (22%), Positives = 51/115 (44%) Frame = +3 Query: 204 AARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXX 383 AA +GD + L S P ++ D+L RTPL + + L KH Sbjct: 17 AAVTGDKTTLLKLIASSPEVIDQEDQLGRTPLMYSVLGDRRSCAEALLKHGAQVNHPDRS 76 Query: 384 XXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVR 548 +H A+Q G+ +++ LL+ A ++ + TA+H + ++ + +++ Sbjct: 77 GRTALHLAAQTGNHRLLKLLLSRKADCTHRDLRDITAVHLSTRHQDTRCLALILK 131 Score = 44.3 bits (103), Expect = 2e-04 Identities = 38/126 (30%), Positives = 60/126 (47%), Gaps = 7/126 (5%) Frame = +3 Query: 189 LKLHKAARSGD---AAAVESLCDSDPLA--LNSRDRLSRTPLHLAAWAGHVDVVKCLCKH 353 + LH AA D A V L ++ P LN +D RTPLHLA G+ +VV+ L + Sbjct: 180 IPLHWAAGHKDPEAALTVRCLLEAAPTESLLNWQDYEGRTPLHLAVGDGNQEVVRLLTSY 239 Query: 354 KX-XXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVK-AKNRKGFTALHFAAQNSHLE 527 + +H+A+ G+ + LL + S + +G T LH+AAQ + + Sbjct: 240 RGCNVAPYDNLFRTPLHWAALLGYTPIAHLLLETNNSPNIPSDSQGATPLHYAAQGNCPD 299 Query: 528 LVKYLV 545 V+ L+ Sbjct: 300 TVRVLL 305 Score = 42.4 bits (98), Expect = 0.001 Identities = 29/102 (28%), Positives = 48/102 (47%), Gaps = 2/102 (1%) Frame = +3 Query: 264 LNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVREL 443 +N DR RT LHLAA G+ ++K L K +H +++ + + Sbjct: 70 VNHPDRSGRTALHLAAQTGNHRLLKLLLSRKADCTHRDLRDITAVHLSTRHQDTRCLALI 129 Query: 444 L--ASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 L V A++++ TALH++A + V+ LVR G +I Sbjct: 130 LKYTPPGQVDAQDQRKQTALHWSAYYNRPRHVRLLVRHGSNI 171
>INVS_CHICK (Q8UVC3) Inversin| Length = 1106 Score = 55.5 bits (132), Expect = 1e-07 Identities = 32/120 (26%), Positives = 57/120 (47%), Gaps = 1/120 (0%) Frame = +3 Query: 204 AARSGDAAAVESLCDSD-PLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXX 380 AA G + ++ D + +N D+ + T LH AA +GHV VK L + Sbjct: 329 AAGKGSDNVIRTMLDLKLDIDINMTDKYAGTALHAAALSGHVSTVKLLLERNAQVDALDV 388 Query: 381 XXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVD 560 + A + GH EV++ L+ GA V ++ G + LH+AA + ++ + L+ ++ Sbjct: 389 MKHTPLFRACEMGHKEVIQTLIKGGARVDLVDQDGHSPLHWAALGGNADVCQILIENKIN 448 Score = 50.4 bits (119), Expect = 3e-06 Identities = 34/124 (27%), Positives = 55/124 (44%), Gaps = 1/124 (0%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLC-KHKXXXXX 371 LH A G+ A V+ L + + S D L RTPLH AA GH +V L ++K Sbjct: 225 LHFAVADGNVAVVDVLTSYEGCNVTSYDNLFRTPLHWAALLGHAQIVHLLLERNKFGTIP 284 Query: 372 XXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRR 551 +H+A+Q E V L + + +G T+ +AA +++ ++ Sbjct: 285 SDSQGATPLHYAAQSNFAETVEVFLKHPSVKDDSDLEGRTSFMWAAGKGSDNVIRTMLDL 344 Query: 552 GVDI 563 +DI Sbjct: 345 KLDI 348 Score = 50.4 bits (119), Expect = 3e-06 Identities = 30/119 (25%), Positives = 53/119 (44%) Frame = +3 Query: 192 KLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXX 371 ++H AA +GD + + L + + D+ RTPL A VD + L K Sbjct: 17 EVHAAAVNGDKSTLLKLIAGNSELKDKEDQFGRTPLMYCVLADRVDCAEALLKAGADVNR 76 Query: 372 XXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVR 548 +H A+QKG+ ++ LLA + K+ +G T LH ++ + + L++ Sbjct: 77 ADRSRRTALHLAAQKGNYRFMKLLLARRGNWMQKDLEGMTPLHLTTRHKSPKCLALLLK 135 Score = 48.5 bits (114), Expect = 1e-05 Identities = 37/127 (29%), Positives = 62/127 (48%), Gaps = 7/127 (5%) Frame = +3 Query: 189 LKLHKAARSGDAAAVES---LCDSDPLA--LNSRDRLSRTPLHLAAWAGHVDVVKCLCKH 353 + LH AA + D +A+ + + ++ P LN +D RTPLH A G+V VV L + Sbjct: 184 IPLHWAANNKDPSAIHTVKCILEAAPTESLLNWQDYEGRTPLHFAVADGNVAVVDVLTSY 243 Query: 354 KX-XXXXXXXXXXXXIHFASQKGHLEVVRELLASGA-SVKAKNRKGFTALHFAAQNSHLE 527 + +H+A+ GH ++V LL + +G T LH+AAQ++ E Sbjct: 244 EGCNVTSYDNLFRTPLHWAALLGHAQIVHLLLERNKFGTIPSDSQGATPLHYAAQSNFAE 303 Query: 528 LVKYLVR 548 V+ ++ Sbjct: 304 TVEVFLK 310 Score = 34.3 bits (77), Expect = 0.26 Identities = 25/112 (22%), Positives = 53/112 (47%), Gaps = 7/112 (6%) Frame = +3 Query: 255 PLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGH---- 422 P ++++DR +T LH +A+ + + VK L KH +H+A+ Sbjct: 139 PGEVDTQDRNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDIEGKIPLHWAANNKDPSAI 198 Query: 423 --LEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVR-RGVDITT 569 ++ + E + + + ++ +G T LHFA + ++ +V L G ++T+ Sbjct: 199 HTVKCILEAAPTESLLNWQDYEGRTPLHFAVADGNVAVVDVLTSYEGCNVTS 250
>CSKI1_HUMAN (Q8WXD9) Caskin-1 (CASK-interacting protein 1)| Length = 1431 Score = 55.1 bits (131), Expect = 1e-07 Identities = 38/131 (29%), Positives = 62/131 (47%), Gaps = 8/131 (6%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AA G ++ + + A+N PLHLAA GH DV + L +H+ Sbjct: 86 LHYAAWQGRKEPMKLVLKAGS-AVNIPSDEGHIPLHLAAQHGHYDVSEMLLQHQSNPCMV 144 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASV--------KAKNRKGFTALHFAAQNSHLEL 530 + A + G + VV+ LL+S A + G + LH AA+N H+++ Sbjct: 145 DNSGKTPLDLACEFGRVGVVQLLLSSNMCAALLEPRPGDATDPNGTSPLHLAAKNGHIDI 204 Query: 531 VKYLVRRGVDI 563 ++ L++ G+DI Sbjct: 205 IRLLLQAGIDI 215 Score = 50.4 bits (119), Expect = 3e-06 Identities = 39/134 (29%), Positives = 61/134 (45%), Gaps = 10/134 (7%) Frame = +3 Query: 189 LKLHKAARSGDAAAVESLCD--SDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXX 362 + LH AA+ G E L S+P + D +TPL LA G V VV+ L Sbjct: 117 IPLHLAAQHGHYDVSEMLLQHQSNPCMV---DNSGKTPLDLACEFGRVGVVQLLLSSNMC 173 Query: 363 XX--------XXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNS 518 +H A++ GH++++R LL +G + + + G TALH AA Sbjct: 174 AALLEPRPGDATDPNGTSPLHLAAKNGHIDIIRLLLQAGIDINRQTKSG-TALHEAALCG 232 Query: 519 HLELVKYLVRRGVD 560 E+V+ L+ G++ Sbjct: 233 KTEVVRLLLDSGIN 246 Score = 43.9 bits (102), Expect = 3e-04 Identities = 28/119 (23%), Positives = 60/119 (50%) Frame = +3 Query: 192 KLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXX 371 +L + R G A + S + + +N +D + LH AA G+ +++ L + + Sbjct: 21 RLLQRPRPGKAKLLGS---TKKINVNFQDPDGFSALHHAALNGNTELISLLLEAQAAVDI 77 Query: 372 XXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVR 548 +H+A+ +G E ++ +L +G++V + +G LH AAQ+ H ++ + L++ Sbjct: 78 KDNKGMRPLHYAAWQGRKEPMKLVLKAGSAVNIPSDEGHIPLHLAAQHGHYDVSEMLLQ 136 Score = 43.1 bits (100), Expect = 5e-04 Identities = 28/87 (32%), Positives = 41/87 (47%) Frame = +3 Query: 252 DPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEV 431 +P ++ D +PLHLAA GH+D+++ L + +H A+ G EV Sbjct: 178 EPRPGDATDPNGTSPLHLAAKNGHIDIIRLLLQ-AGIDINRQTKSGTALHEAALCGKTEV 236 Query: 432 VRELLASGASVKAKNRKGFTALHFAAQ 512 VR LL SG + +N TAL Q Sbjct: 237 VRLLLDSGINAHVRNTYSQTALDIVHQ 263
>BARD1_MOUSE (O70445) BRCA1-associated RING domain protein 1 (BARD-1)| Length = 765 Score = 55.1 bits (131), Expect = 1e-07 Identities = 35/96 (36%), Positives = 49/96 (51%), Gaps = 2/96 (2%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDS--DPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXX 368 LH A+ GD +VE L + DP N +D TPLH A GH+ VV+ L +H Sbjct: 420 LHIASIKGDIPSVEYLLQNGNDP---NVKDHAGWTPLHEACSHGHLKVVELLLQHNALVN 476 Query: 369 XXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKN 476 +H A + GH+++V+ LL+ GAS A N Sbjct: 477 TPGYQNDSPLHDAVKSGHIDIVKVLLSHGASRNAVN 512 Score = 45.8 bits (107), Expect = 8e-05 Identities = 28/102 (27%), Positives = 46/102 (45%) Frame = +3 Query: 249 SDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLE 428 S + R+ T LH+A+ G + V+ L ++ +H A GHL+ Sbjct: 404 SSGMPARKRNHRGETLLHIASIKGDIPSVEYLLQNGNDPNVKDHAGWTPLHEACSHGHLK 463 Query: 429 VVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 VV LL A V + + LH A ++ H+++VK L+ G Sbjct: 464 VVELLLQHNALVNTPGYQNDSPLHDAVKSGHIDIVKVLLSHG 505 Score = 40.8 bits (94), Expect = 0.003 Identities = 20/58 (34%), Positives = 32/58 (55%) Frame = +3 Query: 396 IHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDITT 569 +H AS KG + V LL +G K+ G+T LH A + HL++V+ L++ + T Sbjct: 420 LHIASIKGDIPSVEYLLQNGNDPNVKDHAGWTPLHEACSHGHLKVVELLLQHNALVNT 477 Score = 31.6 bits (70), Expect = 1.7 Identities = 14/39 (35%), Positives = 23/39 (58%) Frame = +3 Query: 444 LASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVD 560 L+SG + +N +G T LH A+ + V+YL++ G D Sbjct: 403 LSSGMPARKRNHRGETLLHIASIKGDIPSVEYLLQNGND 441
>ASB2_MOUSE (Q8K0L0) Ankyrin repeat and SOCS box protein 2 (ASB-2)| Length = 634 Score = 55.1 bits (131), Expect = 1e-07 Identities = 32/117 (27%), Positives = 57/117 (48%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH++ D +E L S + +++ S TPL +AA +G ++ ++ L KH Sbjct: 242 LHESVSRNDLEVMEILV-SGGAKVEAKNVYSITPLFVAAQSGQLEALRFLAKHGADINTQ 300 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLV 545 ++ AS+ H +VV LL+ GA N+ G LH A++ + +V+ L+ Sbjct: 301 ASDSASALYEASKNEHEDVVEFLLSQGADANKANKDGLLPLHVASKKGNYRIVQMLL 357 Score = 53.9 bits (128), Expect = 3e-07 Identities = 29/93 (31%), Positives = 47/93 (50%) Frame = +3 Query: 291 TPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKA 470 TPL+ A + + V+ L ++ +H + + LEV+ L++ GA V+A Sbjct: 207 TPLYKACERKNAEAVRILVRYNADANHRCNRGWTALHESVSRNDLEVMEILVSGGAKVEA 266 Query: 471 KNRKGFTALHFAAQNSHLELVKYLVRRGVDITT 569 KN T L AAQ+ LE +++L + G DI T Sbjct: 267 KNVYSITPLFVAAQSGQLEALRFLAKHGADINT 299 Score = 49.3 bits (116), Expect = 8e-06 Identities = 32/125 (25%), Positives = 57/125 (45%) Frame = +3 Query: 189 LKLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXX 368 L LH+AA G ++ L + P ++ R T L+LA H+D + L + Sbjct: 140 LPLHEAAYYGQLGCLKVLQQAYPGTIDQRTLQEETALYLATCREHLDCLLSLLQAGAEPD 199 Query: 369 XXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVR 548 ++ A ++ + E VR L+ A + +G+TALH + + LE+++ LV Sbjct: 200 ISNKSRETPLYKACERKNAEAVRILVRYNADANHRCNRGWTALHESVSRNDLEVMEILVS 259 Query: 549 RGVDI 563 G + Sbjct: 260 GGAKV 264 Score = 45.8 bits (107), Expect = 8e-05 Identities = 33/122 (27%), Positives = 56/122 (45%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 L+KA +A AV L + A N R T LH + ++V++ L Sbjct: 209 LYKACERKNAEAVRILVRYNADA-NHRCNRGWTALHESVSRNDLEVMEILVSGGAKVEAK 267 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 + A+Q G LE +R L GA + + +AL+ A++N H ++V++L+ +G Sbjct: 268 NVYSITPLFVAAQSGQLEALRFLAKHGADINTQASDSASALYEASKNEHEDVVEFLLSQG 327 Query: 555 VD 560 D Sbjct: 328 AD 329 Score = 33.5 bits (75), Expect = 0.44 Identities = 32/132 (24%), Positives = 60/132 (45%), Gaps = 10/132 (7%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 L++A+++ VE L A N ++ PLH+A+ G+ +V+ L Sbjct: 308 LYEASKNEHEDVVEFLLSQGADA-NKANKDGLLPLHVASKKGNYRIVQMLLP-VTSRTRV 365 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKA----------KNRKGFTALHFAAQNSHL 524 +H A+++ H V+ LLA+ V A ++R+ +AL+FA N+++ Sbjct: 366 RRSGISPLHLAAERNHDAVLEALLAARFDVNAPLAPERARLYEDRRS-SALYFAVVNNNV 424 Query: 525 ELVKYLVRRGVD 560 + L+ G D Sbjct: 425 YATELLLLAGAD 436
>NFKB1_HUMAN (P19838) Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor| KBF1) (EBP-1) [Contains: Nuclear factor NF-kappa-B p50 subunit] Length = 968 Score = 54.7 bits (130), Expect = 2e-07 Identities = 46/132 (34%), Positives = 61/132 (46%), Gaps = 7/132 (5%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH A + VE L + L+ DRL + LHLAA GH V+ L KHK Sbjct: 586 LHLAVITKQEDVVEDLLRAGA-DLSLLDRLGNSVLHLAAKEGHDKVLSILLKHKKAALLL 644 Query: 375 XX---XXXXXIHFASQKGHLEVVRELLASGASVKAKNRK-GFTALHFAAQNSHLELVKYL 542 IH A L + L+A+GA V A+ +K G TALH A ++ ++ L L Sbjct: 645 DHPNGDGLNAIHLAMMSNSLPCLLLLVAAGADVNAQEQKSGRTALHLAVEHDNISLAGCL 704 Query: 543 VRRG---VDITT 569 + G VD TT Sbjct: 705 LLEGDAHVDSTT 716 Score = 46.2 bits (108), Expect = 6e-05 Identities = 35/118 (29%), Positives = 54/118 (45%), Gaps = 3/118 (2%) Frame = +3 Query: 219 DAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXI 398 D V S SD + +N R+ L +TPLHLA DVV+ L + + Sbjct: 561 DLLEVTSGLISDDI-INMRNDLYQTPLHLAVITKQEDVVEDLLRAGADLSLLDRLGNSVL 619 Query: 399 HFASQKGHLEVVRELL---ASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 H A+++GH +V+ LL + + N G A+H A ++ L + LV G D+ Sbjct: 620 HLAAKEGHDKVLSILLKHKKAALLLDHPNGDGLNAIHLAMMSNSLPCLLLLVAAGADV 677
>ANR18_HUMAN (Q8IVF6) Ankyrin repeat domain-containing protein 18A| Length = 992 Score = 54.7 bits (130), Expect = 2e-07 Identities = 45/128 (35%), Positives = 59/128 (46%), Gaps = 4/128 (3%) Frame = +3 Query: 192 KLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCL----CKHKX 359 K+H+AA GDAA VE L++RDR RT LHLA G V VV L C+ Sbjct: 37 KIHRAAIKGDAAEVERCLTRRFRDLDARDRKDRTVLHLACAHGRVQVVTLLLHRRCQIDI 96 Query: 360 XXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKY 539 +H SQ+ +V LL GA+ K+ G TALH+A N L + Sbjct: 97 CDRLNRTPLMKAVH--SQEEACAIV--LLECGANPNIKDIYGNTALHYAVYNKGTSLAER 152 Query: 540 LVRRGVDI 563 L+ +I Sbjct: 153 LLSHHANI 160
>ANR12_HUMAN (Q6UB98) Ankyrin repeat domain-containing protein 12 (Ankyrin| repeat-containing cofactor 2) (GAC-1 protein) Length = 2062 Score = 54.7 bits (130), Expect = 2e-07 Identities = 32/97 (32%), Positives = 47/97 (48%) Frame = +3 Query: 264 LNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVREL 443 +N R+ TPLH+AA G V VK L +H A G+ +V + L Sbjct: 178 VNKRNERGETPLHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNVGYYDVAKIL 237 Query: 444 LASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 +A+GA V + T LH +A + H ++VK L+R G Sbjct: 238 IAAGADVNTQGLDDDTPLHDSASSGHRDIVKLLLRHG 274 Score = 45.4 bits (106), Expect = 1e-04 Identities = 20/58 (34%), Positives = 36/58 (62%) Frame = +3 Query: 396 IHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDITT 569 +H A+ +G ++ V+EL++ GA+V K+ G+T LH A + ++ K L+ G D+ T Sbjct: 189 LHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNVGYYDVAKILIAAGADVNT 246 Score = 31.6 bits (70), Expect = 1.7 Identities = 20/55 (36%), Positives = 30/55 (54%), Gaps = 2/55 (3%) Frame = +3 Query: 195 LHKAARSG--DAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKH 353 LH+A G D A + +D +N++ TPLH +A +GH D+VK L +H Sbjct: 222 LHEACNVGYYDVAKILIAAGAD---VNTQGLDDDTPLHDSASSGHRDIVKLLLRH 273
>IKBA_CHICK (Q91974) NF-kappa-B inhibitor alpha (I-kappa-B-alpha)| (IkappaBalpha) (IKB-alpha) (REL-associated protein pp40) Length = 318 Score = 54.7 bits (130), Expect = 2e-07 Identities = 45/134 (33%), Positives = 59/134 (44%), Gaps = 11/134 (8%) Frame = +3 Query: 195 LHKAARSGDAAAVESL----CDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKH--- 353 LH A + A E L CD L+ RD TPLH+A G + V L +H Sbjct: 119 LHLAVITDQAEIAEHLLKAGCD-----LDVRDFRGNTPLHIACQQGSLRSVSVLTQHCQP 173 Query: 354 ---KXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNR-KGFTALHFAAQNSH 521 +H AS +G+L VV LL+ GA V A+ G TALH A + Sbjct: 174 HHLLAVLQATNYNGHTCLHLASIQGYLAVVEYLLSLGADVNAQEPCNGRTALHLAVDLQN 233 Query: 522 LELVKYLVRRGVDI 563 +LV LV+ G D+ Sbjct: 234 SDLVSLLVKHGPDV 247 Score = 50.8 bits (120), Expect = 3e-06 Identities = 34/110 (30%), Positives = 50/110 (45%), Gaps = 6/110 (5%) Frame = +3 Query: 252 DPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEV 431 D LN ++ LS+TPLHLA ++ + L K +H A Q+G L Sbjct: 104 DAAFLNFQNNLSQTPLHLAVITDQAEIAEHLLKAGCDLDVRDFRGNTPLHIACQQGSLRS 163 Query: 432 VRELLASG------ASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 V L A ++A N G T LH A+ +L +V+YL+ G D+ Sbjct: 164 VSVLTQHCQPHHLLAVLQATNYNGHTCLHLASIQGYLAVVEYLLSLGADV 213 Score = 31.2 bits (69), Expect = 2.2 Identities = 14/47 (29%), Positives = 24/47 (51%) Frame = +3 Query: 423 LEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 LEV+R+ A + +N T LH A E+ ++L++ G D+ Sbjct: 95 LEVIRQAAGDAAFLNFQNNLSQTPLHLAVITDQAEIAEHLLKAGCDL 141
>FANK1_RAT (Q66H07) Fibronectin type 3 and ankyrin repeat domains 1 protein| Length = 344 Score = 54.7 bits (130), Expect = 2e-07 Identities = 31/122 (25%), Positives = 58/122 (47%) Frame = +3 Query: 198 HKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXX 377 H+A D + + + + ++ ++ T L +AA G+ +VK L + Sbjct: 115 HRAVNVNDEDLLLRILEGGHVMVDVPNKFGFTALMVAAQKGYTRLVKILISNGTDVNLKN 174 Query: 378 XXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGV 557 + A GHL+VV+ L GAS A++ G TALH+AA H ++ ++++ G Sbjct: 175 GSGKDSLMLACYAGHLDVVKYLRKHGASWDARDLGGCTALHWAADGGHCPVIDWMIKDGC 234 Query: 558 DI 563 ++ Sbjct: 235 EV 236 Score = 50.1 bits (118), Expect = 4e-06 Identities = 41/156 (26%), Positives = 64/156 (41%), Gaps = 35/156 (22%) Frame = +3 Query: 204 AARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXX 383 AA+ G V+ L S+ +N ++ + L LA +AGH+DVVK L KH Sbjct: 151 AAQKGYTRLVKILI-SNGTDVNLKNGSGKDSLMLACYAGHLDVVKYLRKHGASWDARDLG 209 Query: 384 XXXXIHFASQKGHLEVV-----------------------------------RELLASGA 458 +H+A+ GH V+ L+ +GA Sbjct: 210 GCTALHWAADGGHCPVIDWMIKDGCEVDVVDTGSGWTPLMRVSAVTGSQKVASLLIEAGA 269 Query: 459 SVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDIT 566 V +++ G T L A N+H +LV+ L+ +G D T Sbjct: 270 DVNVRDKDGKTPLMVAVLNNHEQLVQLLLDKGADAT 305
>HOS4_YEAST (P40480) Protein HOS4| Length = 1083 Score = 54.7 bits (130), Expect = 2e-07 Identities = 36/101 (35%), Positives = 53/101 (52%), Gaps = 3/101 (2%) Frame = +3 Query: 273 RDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXX-XXIHFASQKGHLEVVRELLA 449 RD RT L +A G DVVK + + +H A+ +GH+E+V L+ Sbjct: 326 RDSGGRTRLQIACDKGKYDVVKKMIEEGGYDINDQDNAGNTALHEAALQGHIEIVELLIE 385 Query: 450 SGASVKAKNRKGF--TALHFAAQNSHLELVKYLVRRGVDIT 566 +GA V K+ + F T L A+ N HL++VKYL++ G D T Sbjct: 386 NGADVNIKSIEMFGDTPLIDASANGHLDVVKYLLKNGADPT 426 Score = 32.0 bits (71), Expect = 1.3 Identities = 21/54 (38%), Positives = 30/54 (55%), Gaps = 1/54 (1%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDP-LALNSRDRLSRTPLHLAAWAGHVDVVKCLCKH 353 LH+AA G VE L ++ + + S + TPL A+ GH+DVVK L K+ Sbjct: 368 LHEAALQGHIEIVELLIENGADVNIKSIEMFGDTPLIDASANGHLDVVKYLLKN 421 Score = 31.6 bits (70), Expect = 1.7 Identities = 14/31 (45%), Positives = 22/31 (70%) Frame = +3 Query: 414 KGHLEVVRELLASGASVKAKNRKGFTALHFA 506 +GHL V+ LL +GA +++KG TAL++A Sbjct: 604 RGHLGTVKLLLEAGADPTKRDKKGRTALYYA 634
>INVS_CANFA (Q6JAN1) Inversin (Inversion of embryo turning protein)| (Nephrocystin-2) Length = 1081 Score = 54.3 bits (129), Expect = 2e-07 Identities = 30/119 (25%), Positives = 54/119 (45%) Frame = +3 Query: 204 AARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXX 383 A + D L + +N D+ T LH AA +GHV VK L ++ Sbjct: 330 AGKGSDDVLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVM 389 Query: 384 XXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVD 560 + A + GH +V++ L+ GA V ++ G + LH+AA + ++ + L+ ++ Sbjct: 390 KHTPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIENKIN 448 Score = 53.5 bits (127), Expect = 4e-07 Identities = 41/127 (32%), Positives = 62/127 (48%), Gaps = 7/127 (5%) Frame = +3 Query: 189 LKLHKAARSGDAAAVES---LCDSDPLA--LNSRDRLSRTPLHLAAWAGHVDVVKCLCKH 353 + LH AA D +AV + + D+ P LN +D RTPLH A G+V VV L + Sbjct: 184 IPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHFAVADGNVTVVDVLTSY 243 Query: 354 KX-XXXXXXXXXXXXIHFASQKGHLEVVRELLASGAS-VKAKNRKGFTALHFAAQNSHLE 527 + +H+A+ GH ++V LL S + +G T LH+AAQ++ E Sbjct: 244 ESCNITSYDNLFRTPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAE 303 Query: 528 LVKYLVR 548 VK ++ Sbjct: 304 TVKVFLK 310 Score = 51.6 bits (122), Expect = 2e-06 Identities = 41/159 (25%), Positives = 62/159 (38%), Gaps = 36/159 (22%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLC-KHKXXXXX 371 LH A G+ V+ L + + S D L RTPLH AA GH +V L ++K Sbjct: 225 LHFAVADGNVTVVDVLTSYESCNITSYDNLFRTPLHWAALLGHAQIVHLLLERNKSGTIP 284 Query: 372 XXXXXXXXIHFASQ---------------------------------KGHLEVVRELLA- 449 +H+A+Q KG +V+R +L+ Sbjct: 285 SDSQGATPLHYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSDDVLRTMLSL 344 Query: 450 -SGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 S + ++ G TALH AA + H+ VK L+ + Sbjct: 345 KSDIDINMADKYGGTALHAAALSGHVSTVKLLLENNAQV 383 Score = 49.3 bits (116), Expect = 8e-06 Identities = 30/119 (25%), Positives = 52/119 (43%) Frame = +3 Query: 192 KLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXX 371 ++H AA +GD A+ L + + D+ RTPL A +D L K Sbjct: 17 QVHAAAINGDKGALHRLIIGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNK 76 Query: 372 XXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVR 548 +H A+QKG+ ++ LL A+ K+ + T LH A ++ + + L++ Sbjct: 77 TDHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLATRHKSPKCLALLLK 135 Score = 47.8 bits (112), Expect = 2e-05 Identities = 31/122 (25%), Positives = 57/122 (46%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AA SG + V+ L +++ +++ D + TPL A GH DV++ L K Sbjct: 361 LHAAALSGHVSTVKLLLENNA-QVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARVDLV 419 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 +H+A+ G+ +V + L+ + + ++ G T L AA ++ + L+ Sbjct: 420 DQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENN 479 Query: 555 VD 560 D Sbjct: 480 AD 481 Score = 32.0 bits (71), Expect = 1.3 Identities = 25/102 (24%), Positives = 47/102 (46%), Gaps = 6/102 (5%) Frame = +3 Query: 255 PLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFAS---QKGHL 425 P ++++D+ +T LH +A+ + + VK L KH +H+A+ + Sbjct: 139 PGEVDTQDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSAV 198 Query: 426 EVVRELLASGASVKAKN---RKGFTALHFAAQNSHLELVKYL 542 VR +L + + N +G T LHFA + ++ +V L Sbjct: 199 HTVRCILDAAPTESLLNWQDYEGRTPLHFAVADGNVTVVDVL 240
>YR848_MIMIV (Q5UP11) Putative ankyrin repeat protein R848| Length = 262 Score = 54.3 bits (129), Expect = 2e-07 Identities = 33/89 (37%), Positives = 48/89 (53%) Frame = +3 Query: 297 LHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKN 476 L LA+ GH+ VVK L + +AS+ GH EVV+ L+ GA ++ Sbjct: 13 LSLASKNGHIKVVKYLVSKDANVTHDNNYA---VRYASENGHFEVVKYLVDQGADIRDCR 69 Query: 477 RKGFTALHFAAQNSHLELVKYLVRRGVDI 563 A+ FA++N HLE+VKYLV +G +I Sbjct: 70 DY---AVRFASENGHLEVVKYLVDKGANI 95 Score = 51.6 bits (122), Expect = 2e-06 Identities = 38/120 (31%), Positives = 61/120 (50%) Frame = +3 Query: 204 AARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXX 383 A+ +G V+ L D + RD R A+ GH++VVK L Sbjct: 46 ASENGHFEVVKYLVDQGADIRDCRDYAVR----FASENGHLEVVKYLVDK---GANIRAL 98 Query: 384 XXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 + AS G++E+V+ L++ GA+ +A N A+ FA++N +LE+VK+LV +G DI Sbjct: 99 DDYAVCLASVNGYIEIVKYLVSQGANFRADNDY---AVRFASENGYLEVVKFLVDQGADI 155 Score = 50.8 bits (120), Expect = 3e-06 Identities = 38/125 (30%), Positives = 61/125 (48%) Frame = +3 Query: 186 DLKLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXX 365 D L A+++G V+ L D + + R A+ GH +VVK L Sbjct: 10 DYALSLASKNGHIKVVKYLVSKDANVTHDNNYAVR----YASENGHFEVVKYLVDQ---G 62 Query: 366 XXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLV 545 + FAS+ GHLEVV+ L+ GA+++A + A+ A+ N ++E+VKYLV Sbjct: 63 ADIRDCRDYAVRFASENGHLEVVKYLVDKGANIRALDD---YAVCLASVNGYIEIVKYLV 119 Query: 546 RRGVD 560 +G + Sbjct: 120 SQGAN 124 Score = 44.7 bits (104), Expect = 2e-04 Identities = 36/125 (28%), Positives = 61/125 (48%) Frame = +3 Query: 186 DLKLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXX 365 D + A+ +G V+ L D N R L + LA+ G++++VK L Sbjct: 70 DYAVRFASENGHLEVVKYLVDK---GANIR-ALDDYAVCLASVNGYIEIVKYLVSQ---G 122 Query: 366 XXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLV 545 + FAS+ G+LEVV+ L+ GA ++A + A+ A+ HLE++K+L+ Sbjct: 123 ANFRADNDYAVRFASENGYLEVVKFLVDQGADIRADDD---YAIISASVYGHLEVIKFLM 179 Query: 546 RRGVD 560 +G D Sbjct: 180 SQGAD 184 Score = 39.3 bits (90), Expect = 0.008 Identities = 25/91 (27%), Positives = 45/91 (49%) Frame = +3 Query: 297 LHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKN 476 + A+ G+++VVK L I AS GHLEV++ L++ GA ++KN Sbjct: 133 VRFASENGYLEVVKFLVDQ---GADIRADDDYAIISASVYGHLEVIKFLMSQGADFRSKN 189 Query: 477 RKGFTALHFAAQNSHLELVKYLVRRGVDITT 569 ++ A + H E+++Y + + D+ T Sbjct: 190 N---ASIKLAIKYKHPEIIEYFLTQCTDVNT 217 Score = 30.0 bits (66), Expect = 4.8 Identities = 14/38 (36%), Positives = 25/38 (65%) Frame = +3 Query: 453 GASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDIT 566 GA+++ N AL A++N H+++VKYLV + ++T Sbjct: 2 GANIRYSNDY---ALSLASKNGHIKVVKYLVSKDANVT 36
>INVS_HUMAN (Q9Y283) Inversin (Inversion of embryo turning homolog)| (Nephrocystin-2) Length = 1065 Score = 54.3 bits (129), Expect = 2e-07 Identities = 30/119 (25%), Positives = 54/119 (45%) Frame = +3 Query: 204 AARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXX 383 A + D L + +N D+ T LH AA +GHV VK L ++ Sbjct: 330 AGKGSDDVLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVM 389 Query: 384 XXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVD 560 + A + GH +V++ L+ GA V ++ G + LH+AA + ++ + L+ ++ Sbjct: 390 KHTPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIENKIN 448 Score = 53.5 bits (127), Expect = 4e-07 Identities = 41/127 (32%), Positives = 62/127 (48%), Gaps = 7/127 (5%) Frame = +3 Query: 189 LKLHKAARSGDAAAVES---LCDSDPLA--LNSRDRLSRTPLHLAAWAGHVDVVKCLCKH 353 + LH AA D +AV + + D+ P LN +D RTPLH A G+V VV L + Sbjct: 184 IPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHFAVADGNVTVVDVLTSY 243 Query: 354 KX-XXXXXXXXXXXXIHFASQKGHLEVVRELLASGAS-VKAKNRKGFTALHFAAQNSHLE 527 + +H+A+ GH ++V LL S + +G T LH+AAQ++ E Sbjct: 244 ESCNITSYDNLFRTPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAE 303 Query: 528 LVKYLVR 548 VK ++ Sbjct: 304 TVKVFLK 310 Score = 51.6 bits (122), Expect = 2e-06 Identities = 41/159 (25%), Positives = 62/159 (38%), Gaps = 36/159 (22%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLC-KHKXXXXX 371 LH A G+ V+ L + + S D L RTPLH AA GH +V L ++K Sbjct: 225 LHFAVADGNVTVVDVLTSYESCNITSYDNLFRTPLHWAALLGHAQIVHLLLERNKSGTIP 284 Query: 372 XXXXXXXXIHFASQ---------------------------------KGHLEVVRELLA- 449 +H+A+Q KG +V+R +L+ Sbjct: 285 SDSQGATPLHYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSDDVLRTMLSL 344 Query: 450 -SGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 S + ++ G TALH AA + H+ VK L+ + Sbjct: 345 KSDIDINMADKYGGTALHAAALSGHVSTVKLLLENNAQV 383 Score = 48.1 bits (113), Expect = 2e-05 Identities = 29/119 (24%), Positives = 52/119 (43%) Frame = +3 Query: 192 KLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXX 371 ++H AA +GD A++ L + + D+ RTPL A +D L K Sbjct: 17 QVHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNK 76 Query: 372 XXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVR 548 +H A+QKG+ ++ LL A+ K+ + T LH ++ + + L++ Sbjct: 77 TDHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLALLLK 135 Score = 47.8 bits (112), Expect = 2e-05 Identities = 31/122 (25%), Positives = 57/122 (46%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AA SG + V+ L +++ +++ D + TPL A GH DV++ L K Sbjct: 361 LHAAALSGHVSTVKLLLENNA-QVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARVDLV 419 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 +H+A+ G+ +V + L+ + + ++ G T L AA ++ + L+ Sbjct: 420 DQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENN 479 Query: 555 VD 560 D Sbjct: 480 AD 481 Score = 32.0 bits (71), Expect = 1.3 Identities = 25/102 (24%), Positives = 47/102 (46%), Gaps = 6/102 (5%) Frame = +3 Query: 255 PLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFAS---QKGHL 425 P ++++D+ +T LH +A+ + + VK L KH +H+A+ + Sbjct: 139 PGEVDTQDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSAV 198 Query: 426 EVVRELLASGASVKAKN---RKGFTALHFAAQNSHLELVKYL 542 VR +L + + N +G T LHFA + ++ +V L Sbjct: 199 HTVRCILDAAPTESLLNWQDYEGRTPLHFAVADGNVTVVDVL 240
>LITA_LATMA (Q02989) Alpha-latroinsectotoxin precursor (Alpha-LIT) (Fragment)| Length = 1411 Score = 54.3 bits (129), Expect = 2e-07 Identities = 35/112 (31%), Positives = 57/112 (50%), Gaps = 1/112 (0%) Frame = +3 Query: 231 VESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFAS 410 VE L D P D TP+ +A +A V ++ L ++ A+ Sbjct: 1063 VEYLSDKIPDINGKCDVQENTPITVAIFANKVSILNYLVGI-GADPNQQVDGDPPLYIAA 1121 Query: 411 QKGHLEVVRELL-ASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 ++G E+VR L+ + +N++ FTALH AA+N +++VKYLVR+G D+ Sbjct: 1122 RQGRFEIVRCLIEVHKVDINTRNKERFTALHAAARNDFMDVVKYLVRQGADV 1173 Score = 53.1 bits (126), Expect = 5e-07 Identities = 30/121 (24%), Positives = 53/121 (43%) Frame = +3 Query: 189 LKLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXX 368 + +H+A +G V L + DP +N ++ + P +LA + D+ Sbjct: 838 MPIHEAVSNGHLEIVRILIEKDPSLMNVKNIRNEYPFYLAVEKRYKDIFDYFVSKDANVN 897 Query: 369 XXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVR 548 +H S G LEVV+ L+ +GA+ + KN + T A +N L +V + V Sbjct: 898 EVDHNGNTLLHLFSSTGELEVVQFLMQNGANFRLKNNERKTFFDLAIENGRLNIVAFAVE 957 Query: 549 R 551 + Sbjct: 958 K 958 Score = 52.8 bits (125), Expect = 7e-07 Identities = 32/119 (26%), Positives = 54/119 (45%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AAR ++L D + LN++D+ TPLHL+ + + Sbjct: 572 LHLAARRDLTDVTQTLIDITEIDLNAQDKSGFTPLHLSISSTSETAAILIRNTNAVINIK 631 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRR 551 +H A+ + +L V + L GA + + G T LH+AA +LE+V +L+ + Sbjct: 632 SKVGLTPLHLATLQNNLSVSKLLAGKGAYLNDGDANGMTPLHYAAMTGNLEMVDFLLNQ 690 Score = 44.7 bits (104), Expect = 2e-04 Identities = 32/121 (26%), Positives = 55/121 (45%), Gaps = 2/121 (1%) Frame = +3 Query: 195 LHKAARSGDAAAVESLC--DSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXX 368 LH A+ +G+ V L ++D L S+ + LHL + ++ L + Sbjct: 741 LHLASATGNKQLVIELLAKNADVTRLTSK---GFSALHLGIIGKNEEIPFFLVEKGANVN 797 Query: 369 XXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVR 548 +HFA+ G + R LL+ GA +KA++ +H A N HLE+V+ L+ Sbjct: 798 DKTNSGVTPLHFAAGLGKANIFRLLLSRGADIKAEDINSQMPIHEAVSNGHLEIVRILIE 857 Query: 549 R 551 + Sbjct: 858 K 858 Score = 44.3 bits (103), Expect = 2e-04 Identities = 42/158 (26%), Positives = 60/158 (37%), Gaps = 35/158 (22%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSR-TPLHLAAWAGHVDVV-KCLCKHKXXXX 368 LH AA +G+ V+ L + + +N+ + + TPLHLA DV + L Sbjct: 672 LHYAAMTGNLEMVDFLLNQQYININAATKEKKWTPLHLAILFKKNDVAERLLSDENLNIR 731 Query: 369 XXXXXXXXXIHFASQKGHLEVVRELLAS-------------------------------- 452 +H AS G+ ++V ELLA Sbjct: 732 LETNGGINPLHLASATGNKQLVIELLAKNADVTRLTSKGFSALHLGIIGKNEEIPFFLVE 791 Query: 453 -GASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 GA+V K G T LHFAA + + L+ RG DI Sbjct: 792 KGANVNDKTNSGVTPLHFAAGLGKANIFRLLLSRGADI 829 Score = 42.4 bits (98), Expect = 0.001 Identities = 25/101 (24%), Positives = 42/101 (41%), Gaps = 1/101 (0%) Frame = +3 Query: 264 LNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVREL 443 +N + TPLH AA G ++ + L IH A GHLE+VR L Sbjct: 796 VNDKTNSGVTPLHFAAGLGKANIFRLLLSRGADIKAEDINSQMPIHEAVSNGHLEIVRIL 855 Query: 444 LASGAS-VKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 + S + KN + + A + + ++ Y V + ++ Sbjct: 856 IEKDPSLMNVKNIRNEYPFYLAVEKRYKDIFDYFVSKDANV 896 Score = 40.4 bits (93), Expect = 0.004 Identities = 32/120 (26%), Positives = 55/120 (45%), Gaps = 2/120 (1%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 +H AA +G+ E L + D L D+ TPLH+AA + D V L + Sbjct: 504 IHAAASAGNYDVGELLLNKDINLLEKADKNGYTPLHIAADSNKNDFVMFLIGNNADVNVR 563 Query: 375 XXXXXXX-IHFASQKGHLEVVRELL-ASGASVKAKNRKGFTALHFAAQNSHLELVKYLVR 548 +H A+++ +V + L+ + + A+++ GFT LH + +S E L+R Sbjct: 564 TKSDLFTPLHLAARRDLTDVTQTLIDITEIDLNAQDKSGFTPLHLSI-SSTSETAAILIR 622 Score = 32.3 bits (72), Expect = 0.97 Identities = 30/103 (29%), Positives = 44/103 (42%), Gaps = 2/103 (1%) Frame = +3 Query: 186 DLKLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXX 365 D L+ AAR G V L + + +N+R++ T LH AA +DVVK L + Sbjct: 1114 DPPLYIAARQGRFEIVRCLIEVHKVDINTRNKERFTALHAAARNDFMDVVKYLVRQGADV 1173 Query: 366 XXXXXXXXXXIHFASQ--KGHLEVVRELLASGASVKAKNRKGF 488 I A + K +L+ R L SG S ++ F Sbjct: 1174 NAKGIDDLRPIDIAGEKAKAYLQSSR-FLRSGHSFQSNEIDSF 1215 Score = 32.3 bits (72), Expect = 0.97 Identities = 17/57 (29%), Positives = 31/57 (54%), Gaps = 1/57 (1%) Frame = +3 Query: 396 IHFASQKGHLEVVRELLASGASVKAK-NRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 IH A+ G+ +V LL ++ K ++ G+T LH AA ++ + V +L+ D+ Sbjct: 504 IHAAASAGNYDVGELLLNKDINLLEKADKNGYTPLHIAADSNKNDFVMFLIGNNADV 560
>MIB2_CHICK (Q5ZIJ9) Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb| homolog 2) Length = 954 Score = 53.9 bits (128), Expect = 3e-07 Identities = 34/119 (28%), Positives = 55/119 (46%) Frame = +3 Query: 207 ARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXX 386 A +AA V L P ++++++ RT L +A++ GH+DVVK L + Sbjct: 440 AALNNAAKVRELLQKYPDKVDNKNQ-GRTALQIASYQGHLDVVKILLQAHATVNLRDEEG 498 Query: 387 XXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 +H+A+ +V R L+A GA N TAL+ A E+V+ L D+ Sbjct: 499 DTALHYAAFGNQADVARVLMAKGAGADLLNNAKCTALYVAVSQGFTEVVQALCELNCDV 557 Score = 50.4 bits (119), Expect = 3e-06 Identities = 34/121 (28%), Positives = 57/121 (47%), Gaps = 1/121 (0%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKH-KXXXXX 371 LH +A G+ A++ + ++S+ T LHLAA H +V + L K + Sbjct: 602 LHYSALKGNKLAIKKILARARQLVDSKKEDGFTALHLAALNNHKEVAEILIKEGRCDVNV 661 Query: 372 XXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRR 551 +H A +GH+ +V+ L++ G+ V A++ G TA+H A + L V R Sbjct: 662 KNNRNQTPLHLAIIQGHVGLVQLLVSEGSDVNAEDEDGDTAMHIALERQQLMSVLMEKRE 721 Query: 552 G 554 G Sbjct: 722 G 722 Score = 38.9 bits (89), Expect = 0.010 Identities = 24/93 (25%), Positives = 37/93 (39%) Frame = +3 Query: 264 LNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVREL 443 +N RD T LH AA+ DV + L ++ A +G EVV+ L Sbjct: 491 VNLRDEEGDTALHYAAFGNQADVARVLMAKGAGADLLNNAKCTALYVAVSQGFTEVVQAL 550 Query: 444 LASGASVKAKNRKGFTALHFAAQNSHLELVKYL 542 V + G T LH+A + +++ L Sbjct: 551 CELNCDVNLPDSHGDTPLHYAITADYKVIIEIL 583 Score = 33.5 bits (75), Expect = 0.44 Identities = 29/124 (23%), Positives = 55/124 (44%), Gaps = 2/124 (1%) Frame = +3 Query: 186 DLKLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXX 365 D LH AA G+ A V + + + + T L++A G +VV+ LC+ Sbjct: 499 DTALHYAA-FGNQADVARVLMAKGAGADLLNNAKCTALYVAVSQGFTEVVQALCELNCDV 557 Query: 366 XXXXXXXXXXIHFASQKGHLEVVRELLASGASVK--AKNRKGFTALHFAAQNSHLELVKY 539 +H+A + +V+ E+L ++ +N +GF LH++A + +K Sbjct: 558 NLPDSHGDTPLHYAITADY-KVIIEILTEVPNIDFTVQNCQGFNLLHYSALKGNKLAIKK 616 Query: 540 LVRR 551 ++ R Sbjct: 617 ILAR 620
>CSKI2_HUMAN (Q8WXE0) Caskin-2| Length = 1202 Score = 53.9 bits (128), Expect = 3e-07 Identities = 41/135 (30%), Positives = 62/135 (45%), Gaps = 10/135 (7%) Frame = +3 Query: 189 LKLHKAARSGDAAAVESLCD--SDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXX 362 + LH AA+ G E L S+P +N + +TPL LA G + V + L Sbjct: 117 IPLHLAAQYGHYEVSEMLLQHQSNPCLVN---KAKKTPLDLACEFGRLKVAQLLLNSHLC 173 Query: 363 XXXXXXXX--------XXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNS 518 +H A++ GH EV+R+LL +G + + + G TALH AA Sbjct: 174 VALLEGEAKDPCDPNYTTPLHLAAKNGHREVIRQLLRAGIEINRQTKTG-TALHEAALYG 232 Query: 519 HLELVKYLVRRGVDI 563 E+V+ L+ GVD+ Sbjct: 233 KTEVVRLLLEGGVDV 247 Score = 53.5 bits (127), Expect = 4e-07 Identities = 40/131 (30%), Positives = 61/131 (46%), Gaps = 8/131 (6%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AA G V L + A+N+ + PLHLAA GH +V + L +H+ Sbjct: 86 LHYAAWQGRLEPVRLLLRASA-AVNAASLDGQIPLHLAAQYGHYEVSEMLLQHQSNPCLV 144 Query: 375 XXXXXXXIHFASQKGHLEVVRELLAS--------GASVKAKNRKGFTALHFAAQNSHLEL 530 + A + G L+V + LL S G + + T LH AA+N H E+ Sbjct: 145 NKAKKTPLDLACEFGRLKVAQLLLNSHLCVALLEGEAKDPCDPNYTTPLHLAAKNGHREV 204 Query: 531 VKYLVRRGVDI 563 ++ L+R G++I Sbjct: 205 IRQLLRAGIEI 215 Score = 51.2 bits (121), Expect = 2e-06 Identities = 35/127 (27%), Positives = 59/127 (46%), Gaps = 12/127 (9%) Frame = +3 Query: 204 AARSGDAAAVESLC------------DSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLC 347 A ++GD V+ L + L +N +D + LH AA G ++++ L Sbjct: 10 AVKNGDVTGVQKLVAKVKATKTKLLGSTKRLNVNYQDADGFSALHHAALGGSLELIALLL 69 Query: 348 KHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLE 527 + + +H+A+ +G LE VR LL + A+V A + G LH AAQ H E Sbjct: 70 EAQATVDIKDSNGMRPLHYAAWQGRLEPVRLLLRASAAVNAASLDGQIPLHLAAQYGHYE 129 Query: 528 LVKYLVR 548 + + L++ Sbjct: 130 VSEMLLQ 136 Score = 48.5 bits (114), Expect = 1e-05 Identities = 31/117 (26%), Positives = 51/117 (43%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AA G + L ++ ++ +D PLH AAW G ++ V+ L + Sbjct: 53 LHHAALGGSLELIALLLEAQA-TVDIKDSNGMRPLHYAAWQGRLEPVRLLLRASAAVNAA 111 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLV 545 +H A+Q GH EV LL ++ N+ T L A + L++ + L+ Sbjct: 112 SLDGQIPLHLAAQYGHYEVSEMLLQHQSNPCLVNKAKKTPLDLACEFGRLKVAQLLL 168 Score = 40.4 bits (93), Expect = 0.004 Identities = 27/74 (36%), Positives = 34/74 (45%) Frame = +3 Query: 291 TPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKA 470 TPLHLAA GH +V++ L + +H A+ G EVVR LL G V Sbjct: 191 TPLHLAAKNGHREVIRQLLR-AGIEINRQTKTGTALHEAALYGKTEVVRLLLEGGVDVNI 249 Query: 471 KNRKGFTALHFAAQ 512 +N TAL Q Sbjct: 250 RNTYNQTALDIVNQ 263
>YR840_MIMIV (Q5URB9) Putative ankyrin repeat protein R840| Length = 526 Score = 53.9 bits (128), Expect = 3e-07 Identities = 31/89 (34%), Positives = 51/89 (57%) Frame = +3 Query: 297 LHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKN 476 + +A+ GH++VVK L + +AS GHLEVV L++ GA +K++ Sbjct: 261 IRIASGNGHLEVVKFLVSK---GCNIRSEIDHAVQWASTNGHLEVVEYLVSQGADIKSEY 317 Query: 477 RKGFTALHFAAQNSHLELVKYLVRRGVDI 563 + ++ A+QN H+E+VKYLV +G +I Sbjct: 318 DR---SVRCASQNGHIEVVKYLVSQGANI 343 Score = 52.4 bits (124), Expect = 9e-07 Identities = 37/120 (30%), Positives = 59/120 (49%) Frame = +3 Query: 204 AARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXX 383 A ++G V+ L N+ +S AA GH+++VK L Sbjct: 206 AVKNGHLEVVKYLVSQSDRCRNNSAIIS------AAENGHIEIVKFLASR---GSNIRID 256 Query: 384 XXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 I AS GHLEVV+ L++ G +++++ A+ +A+ N HLE+V+YLV +G DI Sbjct: 257 DDYTIRIASGNGHLEVVKFLVSKGCNIRSEIDH---AVQWASTNGHLEVVEYLVSQGADI 313 Score = 51.2 bits (121), Expect = 2e-06 Identities = 38/127 (29%), Positives = 61/127 (48%) Frame = +3 Query: 186 DLKLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXX 365 D + A+++G V+ L N D R A+ GH++VV+ L Sbjct: 318 DRSVRCASQNGHIEVVKYLVSQGANIRNINDYAVR----YASENGHIEVVEYLVSQGANI 373 Query: 366 XXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLV 545 A KGH++VV+ L++SGA ++ N + L AA N HLE++KYLV Sbjct: 374 RVDNDSPLLR---ACLKGHIKVVKFLVSSGADIRVNN---YQPLLIAAGNGHLEILKYLV 427 Query: 546 RRGVDIT 566 +GV+++ Sbjct: 428 SQGVNVS 434 Score = 48.9 bits (115), Expect = 1e-05 Identities = 36/120 (30%), Positives = 56/120 (46%) Frame = +3 Query: 204 AARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXX 383 A+ +G VE L + DR R A+ GH++VVK L Sbjct: 294 ASTNGHLEVVEYLVSQGADIKSEYDRSVRC----ASQNGHIEVVKYLVSQ---GANIRNI 346 Query: 384 XXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 + +AS+ GH+EVV L++ GA+++ N + L A H+++VK+LV G DI Sbjct: 347 NDYAVRYASENGHIEVVEYLVSQGANIRVDND---SPLLRACLKGHIKVVKFLVSSGADI 403 Score = 41.6 bits (96), Expect = 0.002 Identities = 26/83 (31%), Positives = 42/83 (50%) Frame = +3 Query: 297 LHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKN 476 + +A GH+D+VK L I +AS+ GH+E+V+ L++ G + Sbjct: 143 VRIACNNGHIDIVKLLISK---GANIRDYDNCAIKWASENGHIEIVKILVSQGYDSTSNF 199 Query: 477 RKGFTALHFAAQNSHLELVKYLV 545 + + A +N HLE+VKYLV Sbjct: 200 NE---PVILAVKNGHLEVVKYLV 219 Score = 40.8 bits (94), Expect = 0.003 Identities = 26/90 (28%), Positives = 45/90 (50%) Frame = +3 Query: 294 PLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAK 473 PL +AA GH++++K L + I G+ E+V+ L++ GA + Sbjct: 410 PLLIAAGNGHLEILKYLVS-QGVNVSIINVPLVGIACIDGYGYFEIVKYLVSIGADI--- 465 Query: 474 NRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 N A+ A++ HL++VKYLV G ++ Sbjct: 466 NLADDMAIRLASEYGHLDIVKYLVENGANV 495 Score = 40.8 bits (94), Expect = 0.003 Identities = 18/56 (32%), Positives = 34/56 (60%) Frame = +3 Query: 396 IHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 I A + GH+EVV+ L+ +G ++++ A+ A N H+++VK L+ +G +I Sbjct: 113 IKLACEHGHIEVVKYLIDNGVDIRSEKN---YAVRIACNNGHIDIVKLLISKGANI 165 Score = 38.1 bits (87), Expect = 0.018 Identities = 16/56 (28%), Positives = 36/56 (64%) Frame = +3 Query: 396 IHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 + + ++G + V+ ++ GA++++++ A+ A ++ H+E+VKYL+ GVDI Sbjct: 83 LFISCKRGRNDFVKYFVSKGANIRSRDN---FAIKLACEHGHIEVVKYLIDNGVDI 135 Score = 32.0 bits (71), Expect = 1.3 Identities = 19/54 (35%), Positives = 27/54 (50%) Frame = +3 Query: 297 LHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGA 458 + LA+ GH+D+VK L ++ H +KGH EVV LL+ GA Sbjct: 473 IRLASEYGHLDIVKYLVENGANVRAENDYAIKQAH---RKGHQEVVNYLLSKGA 523
>Y045_METMA (Q8Q0U0) Hypothetical ANK-repeat protein MM0045| Length = 360 Score = 53.9 bits (128), Expect = 3e-07 Identities = 29/100 (29%), Positives = 49/100 (49%) Frame = +3 Query: 264 LNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVREL 443 LN +D +T L A GH +V+ L + +A+ +G+ ++V L Sbjct: 226 LNIQDNSGKTALVAATKIGHKGIVELLVNAGADLNLQDKNGNTALIYAADRGYRDIVNLL 285 Query: 444 LASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 + GAS+ + G TAL F+AQ ++V+ L++ G DI Sbjct: 286 IEGGASLNIPDEAGLTALMFSAQTGRKDIVELLIKAGADI 325 Score = 45.1 bits (105), Expect = 1e-04 Identities = 31/123 (25%), Positives = 55/123 (44%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 L AA G + L +S P L+ +D T L AA D++ L K+ Sbjct: 105 LISAADKGYRDVIGLLIESGP-NLDLQDENGNTALISAAKIERGDIIDLLVKNGADLNFQ 163 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 + FA + G+ + +L+ +G + ++ G TAL AA +H ++ + L++ G Sbjct: 164 DENGETALKFAVKVGYKNIADQLIDAGTDLNIQDENGETALICAADRAHRDIAELLIKAG 223 Query: 555 VDI 563 D+ Sbjct: 224 ADL 226 Score = 38.5 bits (88), Expect = 0.014 Identities = 24/100 (24%), Positives = 42/100 (42%) Frame = +3 Query: 264 LNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVREL 443 LN +D T L A G+ ++ L + A+ + H ++ L Sbjct: 160 LNFQDENGETALKFAVKVGYKNIADQLIDAGTDLNIQDENGETALICAADRAHRDIAELL 219 Query: 444 LASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 + +GA + ++ G TAL A + H +V+ LV G D+ Sbjct: 220 IKAGADLNIQDNSGKTALVAATKIGHKGIVELLVNAGADL 259 Score = 35.0 bits (79), Expect = 0.15 Identities = 21/79 (26%), Positives = 39/79 (49%) Frame = +3 Query: 327 DVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFA 506 +V K L +K + A+ KG+ +V+ L+ SG ++ ++ G TAL A Sbjct: 82 NVEKLLRSNKVDVNYQDAYGKTALISAADKGYRDVIGLLIESGPNLDLQDENGNTALISA 141 Query: 507 AQNSHLELVKYLVRRGVDI 563 A+ +++ LV+ G D+ Sbjct: 142 AKIERGDIIDLLVKNGADL 160
>ILK_MOUSE (O55222) Integrin-linked protein kinase (EC 2.7.11.1)| Length = 452 Score = 53.5 bits (127), Expect = 4e-07 Identities = 35/97 (36%), Positives = 49/97 (50%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH A R G +A VE L +N +R TPLHLAA GH D+V+ L ++K Sbjct: 38 LHWACREGRSAVVEMLIMRGA-RINVMNRGDDTPLHLAASHGHRDIVQKLLQYKADTNAV 96 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKG 485 +H+A G +V +L+A+GA V N+ G Sbjct: 97 NEHGNVPLHYACFWGQDQVAEDLVANGALVSICNKYG 133 Score = 49.3 bits (116), Expect = 8e-06 Identities = 34/115 (29%), Positives = 48/115 (41%) Frame = +3 Query: 210 RSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXX 389 R G+A AV D+ LN D +PLH A G VV+ L Sbjct: 9 REGNAVAVRLWLDNTENDLNQGDDHGFSPLHWACREGRSAVVEMLIMRGARINVMNRGDD 68 Query: 390 XXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 +H A+ GH ++V++LL A A N G LH+A ++ + LV G Sbjct: 69 TPLHLAASHGHRDIVQKLLQYKADTNAVNEHGNVPLHYACFWGQDQVAEDLVANG 123 Score = 39.7 bits (91), Expect = 0.006 Identities = 19/55 (34%), Positives = 31/55 (56%) Frame = +3 Query: 396 IHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVD 560 +H+A ++G VV L+ GA + NR T LH AA + H ++V+ L++ D Sbjct: 38 LHWACREGRSAVVEMLIMRGARINVMNRGDDTPLHLAASHGHRDIVQKLLQYKAD 92
>ASB8_MOUSE (Q91ZT9) Ankyrin repeat and SOCS box protein 8 (ASB-8)| Length = 288 Score = 53.5 bits (127), Expect = 4e-07 Identities = 41/123 (33%), Positives = 58/123 (47%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH A DA VE L + +N+ D +RT LH AA V+ L ++ Sbjct: 57 LHCACMVSDADCVELLLEKGA-EVNALDGYNRTALHYAAERDEA-CVEVLLEYGANPNAL 114 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 +H+A+ K + E VR LL SGASV A + T L +AA +LE V L+ G Sbjct: 115 DGNRDTPLHWAAFKNNAECVRALLESGASVNALDYNNDTPLSWAAMKGNLESVSILLDYG 174 Query: 555 VDI 563 ++ Sbjct: 175 AEV 177 Score = 37.0 bits (84), Expect = 0.039 Identities = 24/90 (26%), Positives = 39/90 (43%) Frame = +3 Query: 294 PLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAK 473 PLH A D V+ L + +H+A+++ V LL GA+ A Sbjct: 56 PLHCACMVSDADCVELLLEKGAEVNALDGYNRTALHYAAERDE-ACVEVLLEYGANPNAL 114 Query: 474 NRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 + T LH+AA ++ E V+ L+ G + Sbjct: 115 DGNRDTPLHWAAFKNNAECVRALLESGASV 144
>ASB8_HUMAN (Q9H765) Ankyrin repeat and SOCS box protein 8 (ASB-8)| Length = 288 Score = 53.5 bits (127), Expect = 4e-07 Identities = 41/123 (33%), Positives = 58/123 (47%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH A DA VE L + +N+ D +RT LH AA V+ L ++ Sbjct: 57 LHCACMVSDADCVELLLEKGA-EVNALDGYNRTALHYAAEKDEA-CVEVLLEYGANPNAL 114 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 +H+A+ K + E VR LL SGASV A + T L +AA +LE V L+ G Sbjct: 115 DGNRDTPLHWAAFKNNAECVRALLESGASVNALDYNNDTPLSWAAMKGNLESVSILLDYG 174 Query: 555 VDI 563 ++ Sbjct: 175 AEV 177 Score = 38.1 bits (87), Expect = 0.018 Identities = 25/90 (27%), Positives = 39/90 (43%) Frame = +3 Query: 294 PLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAK 473 PLH A D V+ L + +H+A++K V LL GA+ A Sbjct: 56 PLHCACMVSDADCVELLLEKGAEVNALDGYNRTALHYAAEKDE-ACVEVLLEYGANPNAL 114 Query: 474 NRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 + T LH+AA ++ E V+ L+ G + Sbjct: 115 DGNRDTPLHWAAFKNNAECVRALLESGASV 144
>ASB15_HUMAN (Q8WXK1) Ankyrin repeat and SOCS box protein 15 (ASB-15)| Length = 588 Score = 53.5 bits (127), Expect = 4e-07 Identities = 28/99 (28%), Positives = 51/99 (51%) Frame = +3 Query: 267 NSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELL 446 N+++ TPL +A G D+V L KH +H A+++G ++V LL Sbjct: 138 NTKNDKGETPLLIAVKKGSYDMVSTLIKHNTSLDQPCVKRWSAMHEAAKQGRKDIVALLL 197 Query: 447 ASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 G +V ++ G T L AA+ H +++++L+ +G D+ Sbjct: 198 KHGGNVHLRDGFGVTPLGVAAEYGHCDVLEHLIHKGGDV 236 Score = 30.4 bits (67), Expect = 3.7 Identities = 30/131 (22%), Positives = 53/131 (40%), Gaps = 9/131 (6%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 L +AA G+ + L + N +R P+H AA+ GH +K L Sbjct: 247 LFEAAGGGNPDCISLLLEYGGSG-NVPNRAGHLPIHRAAYEGHYLALKYLIP-VTSKNAI 304 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASV---------KAKNRKGFTALHFAAQNSHLE 527 IH A+ + + + L+ +G V ++ + + TAL+FA N+ + Sbjct: 305 RKSGLTPIHSAADGQNAQCLELLIENGFDVNTLLADHISQSCDDERKTALYFAVSNNDVH 364 Query: 528 LVKYLVRRGVD 560 + L+ G D Sbjct: 365 CTEVLLAAGAD 375
>CSKI1_RAT (Q8VHK2) Caskin-1 (CASK-interacting protein 1)| Length = 1430 Score = 53.5 bits (127), Expect = 4e-07 Identities = 37/131 (28%), Positives = 61/131 (46%), Gaps = 8/131 (6%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AA G ++ + + A+N PLHLAA GH DV + L +H+ Sbjct: 86 LHYAAWQGRKEPMKLVLKAGS-AVNVPSDEGHIPLHLAAQHGHYDVSEMLLQHQSNPCIV 144 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASV--------KAKNRKGFTALHFAAQNSHLEL 530 + A + G + VV+ LL+S + G + LH AA+N H+++ Sbjct: 145 DNSGKTPLDLACEFGRVGVVQLLLSSNMCAALLEPRPGDTTDPNGTSPLHLAAKNGHIDI 204 Query: 531 VKYLVRRGVDI 563 ++ L++ G+DI Sbjct: 205 IRLLLQAGIDI 215 Score = 50.4 bits (119), Expect = 3e-06 Identities = 39/134 (29%), Positives = 61/134 (45%), Gaps = 10/134 (7%) Frame = +3 Query: 189 LKLHKAARSGDAAAVESLCD--SDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXX 362 + LH AA+ G E L S+P + D +TPL LA G V VV+ L Sbjct: 117 IPLHLAAQHGHYDVSEMLLQHQSNPCIV---DNSGKTPLDLACEFGRVGVVQLLLSSNMC 173 Query: 363 XX--------XXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNS 518 +H A++ GH++++R LL +G + + + G TALH AA Sbjct: 174 AALLEPRPGDTTDPNGTSPLHLAAKNGHIDIIRLLLQAGIDINRQTKSG-TALHEAALCG 232 Query: 519 HLELVKYLVRRGVD 560 E+V+ L+ G++ Sbjct: 233 KTEVVRLLLDSGIN 246 Score = 44.3 bits (103), Expect = 2e-04 Identities = 28/119 (23%), Positives = 60/119 (50%) Frame = +3 Query: 192 KLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXX 371 +L + R G A + S + + +N +D + LH AA G+ +++ L + + Sbjct: 21 RLLQRPRPGKAKLLGS---TKKINVNFQDPDGFSALHHAALNGNTELISLLLEAQAAVDI 77 Query: 372 XXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVR 548 +H+A+ +G E ++ +L +G++V + +G LH AAQ+ H ++ + L++ Sbjct: 78 KDNKGMRPLHYAAWQGRKEPMKLVLKAGSAVNVPSDEGHIPLHLAAQHGHYDVSEMLLQ 136 Score = 43.9 bits (102), Expect = 3e-04 Identities = 28/87 (32%), Positives = 42/87 (48%) Frame = +3 Query: 252 DPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEV 431 +P ++ D +PLHLAA GH+D+++ L + +H A+ G EV Sbjct: 178 EPRPGDTTDPNGTSPLHLAAKNGHIDIIRLLLQ-AGIDINRQTKSGTALHEAALCGKTEV 236 Query: 432 VRELLASGASVKAKNRKGFTALHFAAQ 512 VR LL SG + + +N TAL Q Sbjct: 237 VRLLLDSGINAQVRNTYSQTALDIVHQ 263
>SAMD6_RAT (P0C0T2) Sterile alpha motif domain-containing protein 6| (Polycystic kidney disease protein 1) (SamCystin) Length = 871 Score = 53.5 bits (127), Expect = 4e-07 Identities = 35/114 (30%), Positives = 53/114 (46%) Frame = +3 Query: 222 AAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIH 401 A AVE+ P+ ++ D + L LAA GH +V+ L + + Sbjct: 51 ARAVEA---GTPVPVDCSDEAGNSALQLAAAGGHEPLVRFLLRRGASVNSRNHYGWSALM 107 Query: 402 FASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 A++ GH V LL GA V A+NR G + L A++ HL +VK L+ G + Sbjct: 108 QAARCGHASVAHLLLDHGADVNAQNRLGASVLTVASRGGHLGVVKLLLEAGATV 161 Score = 48.1 bits (113), Expect = 2e-05 Identities = 35/114 (30%), Positives = 49/114 (42%), Gaps = 14/114 (12%) Frame = +3 Query: 261 ALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRE 440 ++NSR+ + L AA GH V L H + AS+ GHL VV+ Sbjct: 94 SVNSRNHYGWSALMQAARCGHASVAHLLLDHGADVNAQNRLGASVLTVASRGGHLGVVKL 153 Query: 441 LLASGASVKAKNRK--------------GFTALHFAAQNSHLELVKYLVRRGVD 560 LL +GA+V +N G TAL A Q+ H +V+ L+ G D Sbjct: 154 LLEAGATVDHRNPSGESTASGGSRDELLGITALMAAVQHGHEAVVRLLMEWGAD 207 Score = 45.8 bits (107), Expect = 8e-05 Identities = 35/116 (30%), Positives = 54/116 (46%), Gaps = 3/116 (2%) Frame = +3 Query: 204 AARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLC-KHKXXXXXXXX 380 A + G+ V+ + D DP +N + TPL LAA G + +V+ L KH Sbjct: 290 ALKMGNFQLVKEIADEDPNHVNLVNGDGATPLMLAAVTGQLPLVQLLVEKHADMNKQDSV 349 Query: 381 XXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTA--LHFAAQNSHLELVKYL 542 + A+ G+ E+V+ LL GA V + + G+TA L + ELV+ L Sbjct: 350 HGWTALMQATYHGNKEIVKYLLNQGADVTLRAKNGYTAFDLVMLLNDPDTELVRLL 405
>SAMD6_MOUSE (Q6GQX6) Sterile alpha motif domain-containing protein 6| Length = 883 Score = 53.5 bits (127), Expect = 4e-07 Identities = 35/118 (29%), Positives = 55/118 (46%) Frame = +3 Query: 201 KAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXX 380 +A R+ +A A P+ ++ D + L LAA GH +V+ L + Sbjct: 49 EAVRAAEAGA--------PVPVDCSDEAGNSALQLAAAGGHEPLVRFLLRRGASVNSRNH 100 Query: 381 XXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 + A++ GH+ V LL GA V A+NR G + L A++ HL +VK L+ G Sbjct: 101 YGWSALMQAARCGHVSVAHLLLDHGADVNAQNRLGASVLTVASRGGHLGVVKLLLEAG 158 Score = 48.9 bits (115), Expect = 1e-05 Identities = 36/116 (31%), Positives = 55/116 (47%), Gaps = 3/116 (2%) Frame = +3 Query: 204 AARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLC-KHKXXXXXXXX 380 A + G+ V+ + D DP +N + TPL LAA GH+ +V+ L KH Sbjct: 290 ALKMGNFQLVKEIADEDPNHVNLVNGDGATPLMLAAVTGHLPLVQLLVEKHADMDKQDSV 349 Query: 381 XXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTA--LHFAAQNSHLELVKYL 542 + A+ G+ E+V+ LL GA V + + G+TA L + ELV+ L Sbjct: 350 HGWTALMQATYHGNKEIVKYLLNQGADVALRAKNGYTAFDLVMLLNDPDTELVRLL 405 Score = 45.4 bits (106), Expect = 1e-04 Identities = 35/114 (30%), Positives = 47/114 (41%), Gaps = 14/114 (12%) Frame = +3 Query: 261 ALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRE 440 ++NSR+ + L AA GHV V L H + AS+ GHL VV+ Sbjct: 94 SVNSRNHYGWSALMQAARCGHVSVAHLLLDHGADVNAQNRLGASVLTVASRGGHLGVVKL 153 Query: 441 LLASGASV--------------KAKNRKGFTALHFAAQNSHLELVKYLVRRGVD 560 LL +GA V G TAL A Q+ H +V+ L+ G D Sbjct: 154 LLEAGAIVDHHTPSGESPATGGSGDELLGITALMAAVQHGHEAVVRLLMEWGAD 207 Score = 41.2 bits (95), Expect = 0.002 Identities = 21/56 (37%), Positives = 33/56 (58%) Frame = +3 Query: 396 IHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 + A+ GH +VR LL GASV ++N G++AL AA+ H+ + L+ G D+ Sbjct: 73 LQLAAAGGHEPLVRFLLRRGASVNSRNHYGWSALMQAARCGHVSVAHLLLDHGADV 128
>INVSB_XENLA (Q71S21) Inversin-B| Length = 1002 Score = 53.5 bits (127), Expect = 4e-07 Identities = 30/120 (25%), Positives = 57/120 (47%), Gaps = 1/120 (0%) Frame = +3 Query: 204 AARSGDAAAVESLCDSDP-LALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXX 380 AA G V ++ + +P L +N D+ T LH A+ +G + V+ L +++ Sbjct: 325 AAGKGSDEVVRTMLELNPKLEVNRTDKYGGTALHAASLSGQITTVRILLENRAQADAVDV 384 Query: 381 XXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVD 560 + A + GH EV+ L+ GA V ++ G + LH+AA + + + L+ ++ Sbjct: 385 MKHTPLFRACEMGHREVIATLIKGGAKVHLVDKDGRSPLHWAALGGNANVCQILIENNIN 444 Score = 47.4 bits (111), Expect = 3e-05 Identities = 28/118 (23%), Positives = 52/118 (44%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 + AA +GD + L S P ++ D+L RTPL + + L KH Sbjct: 14 IQAAAVTGDKTTLLRLIASSPQVIDQEDQLGRTPLMYSVLGDRRSCAEALLKHGAKVNRP 73 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVR 548 +H A+Q G+ +++ LL+ A ++ TALH + ++ + + L++ Sbjct: 74 DRSGRTALHLAAQTGNHRLLKLLLSRKADCTHRDLCDITALHLSTRHQDTQCLVLLLK 131 Score = 45.4 bits (106), Expect = 1e-04 Identities = 39/126 (30%), Positives = 59/126 (46%), Gaps = 7/126 (5%) Frame = +3 Query: 189 LKLHKAARSGD---AAAVESLCDSDPLA--LNSRDRLSRTPLHLAAWAGHVDVVKCLCKH 353 + LH AA D A V L ++ P LN +D RTPLHLA G+ +VV+ L + Sbjct: 180 IPLHWAAGHKDPEAALTVRCLFEAAPTESLLNWQDYEGRTPLHLAVGDGNQEVVRLLTSY 239 Query: 354 KX-XXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVK-AKNRKGFTALHFAAQNSHLE 527 + +H+A+ GH + LL S + +G T LH+AAQ + + Sbjct: 240 RGCNVAPYDNLFRTPLHWAALLGHTPIAHLLLERNNSPNIPSDSQGATPLHYAAQGNCPD 299 Query: 528 LVKYLV 545 V+ L+ Sbjct: 300 TVRVLL 305 Score = 43.1 bits (100), Expect = 5e-04 Identities = 30/102 (29%), Positives = 50/102 (49%), Gaps = 2/102 (1%) Frame = +3 Query: 264 LNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVREL 443 +N DR RT LHLAA G+ ++K L K +H +++ + + L Sbjct: 70 VNRPDRSGRTALHLAAQTGNHRLLKLLLSRKADCTHRDLCDITALHLSTRHQDTQCLVLL 129 Query: 444 L--ASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 L V A++++ TALH++A + + V+ LVR G +I Sbjct: 130 LKYTPPGQVDAQDQRKQTALHWSAYYNRPQHVRLLVRHGSNI 171 Score = 42.4 bits (98), Expect = 0.001 Identities = 33/118 (27%), Positives = 51/118 (43%), Gaps = 1/118 (0%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLC-KHKXXXXX 371 LH A G+ V L + D L RTPLH AA GH + L ++ Sbjct: 221 LHLAVGDGNQEVVRLLTSYRGCNVAPYDNLFRTPLHWAALLGHTPIAHLLLERNNSPNIP 280 Query: 372 XXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLV 545 +H+A+Q + VR LL+ + + +G TAL +AA E+V+ ++ Sbjct: 281 SDSQGATPLHYAAQGNCPDTVRVLLSHPSVRDEADLEGRTALMWAAGKGSDEVVRTML 338
>CSKI1_MOUSE (Q6P9K8) Caskin-1 (CASK-interacting protein 1)| Length = 1431 Score = 53.5 bits (127), Expect = 4e-07 Identities = 37/131 (28%), Positives = 61/131 (46%), Gaps = 8/131 (6%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AA G ++ + + A+N PLHLAA GH DV + L +H+ Sbjct: 86 LHYAAWQGRKEPMKLVLKAGS-AVNVPSDEGHIPLHLAAQHGHYDVSEMLLQHQSNPCMV 144 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASV--------KAKNRKGFTALHFAAQNSHLEL 530 + A + G + VV+ LL+S + G + LH AA+N H+++ Sbjct: 145 DNSGKTPLDLACEFGRVGVVQLLLSSNMCAALLEPRPGDTTDPNGTSPLHLAAKNGHIDI 204 Query: 531 VKYLVRRGVDI 563 ++ L++ G+DI Sbjct: 205 IRLLLQAGIDI 215 Score = 50.4 bits (119), Expect = 3e-06 Identities = 39/134 (29%), Positives = 61/134 (45%), Gaps = 10/134 (7%) Frame = +3 Query: 189 LKLHKAARSGDAAAVESLCD--SDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXX 362 + LH AA+ G E L S+P + D +TPL LA G V VV+ L Sbjct: 117 IPLHLAAQHGHYDVSEMLLQHQSNPCMV---DNSGKTPLDLACEFGRVGVVQLLLSSNMC 173 Query: 363 XX--------XXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNS 518 +H A++ GH++++R LL +G + + + G TALH AA Sbjct: 174 AALLEPRPGDTTDPNGTSPLHLAAKNGHIDIIRLLLQAGIDINRQTKSG-TALHEAALCG 232 Query: 519 HLELVKYLVRRGVD 560 E+V+ L+ G++ Sbjct: 233 KTEVVRLLLDSGIN 246 Score = 44.3 bits (103), Expect = 2e-04 Identities = 28/119 (23%), Positives = 60/119 (50%) Frame = +3 Query: 192 KLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXX 371 +L + R G A + S + + +N +D + LH AA G+ +++ L + + Sbjct: 21 RLLQRPRPGKAKLLGS---TKKINVNFQDPDGFSALHHAALNGNTELISLLLEAQAAVDI 77 Query: 372 XXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVR 548 +H+A+ +G E ++ +L +G++V + +G LH AAQ+ H ++ + L++ Sbjct: 78 KDNKGMRPLHYAAWQGRKEPMKLVLKAGSAVNVPSDEGHIPLHLAAQHGHYDVSEMLLQ 136 Score = 43.9 bits (102), Expect = 3e-04 Identities = 28/87 (32%), Positives = 42/87 (48%) Frame = +3 Query: 252 DPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEV 431 +P ++ D +PLHLAA GH+D+++ L + +H A+ G EV Sbjct: 178 EPRPGDTTDPNGTSPLHLAAKNGHIDIIRLLLQ-AGIDINRQTKSGTALHEAALCGKTEV 236 Query: 432 VRELLASGASVKAKNRKGFTALHFAAQ 512 VR LL SG + + +N TAL Q Sbjct: 237 VRLLLDSGINAQVRNTYSQTALDIVHQ 263
>LITD_LATMA (Q25338) Delta-latroinsectotoxin precursor (Delta-LIT)| Length = 1214 Score = 53.5 bits (127), Expect = 4e-07 Identities = 34/123 (27%), Positives = 54/123 (43%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH A A + L D + L + T LHLA G ++++K L K Sbjct: 711 LHFAIYFKKEDAAKELLKQDDINLTIVADGNLTVLHLAVSTGQINIIKELLKRGSNIEEK 770 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 +H A+ + E+ L+ +GA ++A++ T LH AA+ V YL+ +G Sbjct: 771 TGEGYTSLHIAAMRKEPEIAVVLIENGADIEARSADNLTPLHSAAKIGRKSTVLYLLEKG 830 Query: 555 VDI 563 DI Sbjct: 831 ADI 833 Score = 51.2 bits (121), Expect = 2e-06 Identities = 35/121 (28%), Positives = 53/121 (43%), Gaps = 2/121 (1%) Frame = +3 Query: 204 AARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXX 383 A R + A+ L + + + +D+ TPLH+AA AG VK L H Sbjct: 510 AYRGNNKIALRFLLKNQSIDIELKDKNGFTPLHIAAEAGQAGFVKLLINHGADVNAKTSK 569 Query: 384 XXXX-IHFASQKGHLEVVRELLAS-GASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGV 557 +H A++ G + VR LL S V K GFT LH A ++++ + L + Sbjct: 570 TNLTPLHLATRSGFSKTVRNLLESPNIKVNEKEDDGFTPLHTAVMSTYMVVDALLNHPDI 629 Query: 558 D 560 D Sbjct: 630 D 630 Score = 48.9 bits (115), Expect = 1e-05 Identities = 32/118 (27%), Positives = 53/118 (44%), Gaps = 1/118 (0%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH A RSG + V +L +S + +N ++ TPLH A + ++ VV L H Sbjct: 575 LHLATRSGFSKTVRNLLESPNIKVNEKEDDGFTPLHTAVMSTYM-VVDALLNHPDIDKNA 633 Query: 375 XXXXXXX-IHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLV 545 H A EV L+ S A + ++ +HFAA +++++YL+ Sbjct: 634 QSTSGLTPFHLAIINESQEVAESLVESNADLNIQDVNHMAPIHFAASMGSIKMLRYLI 691 Score = 45.1 bits (105), Expect = 1e-04 Identities = 30/123 (24%), Positives = 51/123 (41%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH A +G ++ L + + T LH+AA ++ L ++ Sbjct: 745 LHLAVSTGQINIIKELLKRGS-NIEEKTGEGYTSLHIAAMRKEPEIAVVLIENGADIEAR 803 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 +H A++ G V LL GA + AK G TALH A ++ V+ L+ +G Sbjct: 804 SADNLTPLHSAAKIGRKSTVLYLLEKGADIGAKTADGSTALHLAVSGRKMKTVETLLNKG 863 Query: 555 VDI 563 ++ Sbjct: 864 ANL 866 Score = 39.7 bits (91), Expect = 0.006 Identities = 32/120 (26%), Positives = 49/120 (40%), Gaps = 1/120 (0%) Frame = +3 Query: 195 LHKAA-RSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXX 371 LH AA R AV + + + S D L TPLH AA G V L + Sbjct: 778 LHIAAMRKEPEIAVVLIENGADIEARSADNL--TPLHSAAKIGRKSTVLYLLEKGADIGA 835 Query: 372 XXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRR 551 +H A ++ V LL GA++K + + +H A N L++V+ + + Sbjct: 836 KTADGSTALHLAVSGRKMKTVETLLNKGANLKEYDNNKYLPIHKAIINDDLDMVRLFLEK 895 Score = 36.2 bits (82), Expect = 0.067 Identities = 17/58 (29%), Positives = 30/58 (51%), Gaps = 2/58 (3%) Frame = +3 Query: 396 IHFASQKGHLEVVRELLASGASV--KAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 +H + +G+ ++ L S+ + K++ GFT LH AA+ VK L+ G D+ Sbjct: 506 MHAVAYRGNNKIALRFLLKNQSIDIELKDKNGFTPLHIAAEAGQAGFVKLLINHGADV 563 Score = 35.8 bits (81), Expect = 0.088 Identities = 29/122 (23%), Positives = 51/122 (41%), Gaps = 3/122 (2%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH A S V++L + + N++ TP HLA +V + L + Sbjct: 609 LHTAVMS-TYMVVDALLNHPDIDKNAQSTSGLTPFHLAIINESQEVAESLVESNADLNIQ 667 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKN---RKGFTALHFAAQNSHLELVKYLV 545 IHFA+ G ++++R L++ V + +T LHFA + K L+ Sbjct: 668 DVNHMAPIHFAASMGSIKMLRYLISIKDKVSINSVTENNNWTPLHFAIYFKKEDAAKELL 727 Query: 546 RR 551 ++ Sbjct: 728 KQ 729 Score = 35.4 bits (80), Expect = 0.11 Identities = 31/124 (25%), Positives = 47/124 (37%), Gaps = 1/124 (0%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKH-KXXXXX 371 LH AA +G A V+ L + + + TPLHLA +G V+ L + Sbjct: 541 LHIAAEAGQAGFVKLLINHGADVNAKTSKTNLTPLHLATRSGFSKTVRNLLESPNIKVNE 600 Query: 372 XXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRR 551 +H A ++ V L A++ G T H A N E+ + LV Sbjct: 601 KEDDGFTPLHTAVMSTYMVVDALLNHPDIDKNAQSTSGLTPFHLAIINESQEVAESLVES 660 Query: 552 GVDI 563 D+ Sbjct: 661 NADL 664
>ASB2_RAT (Q5U2S6) Ankyrin repeat and SOCS box protein 2 (ASB-2)| Length = 634 Score = 53.5 bits (127), Expect = 4e-07 Identities = 29/93 (31%), Positives = 47/93 (50%) Frame = +3 Query: 291 TPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKA 470 TPL+ A + + V+ L ++ +H + + LEV+ L++ GA V+A Sbjct: 207 TPLYKACERKNAEAVRILVQYNADANHRCNRGWTALHESVSRNDLEVMEILVSGGAKVEA 266 Query: 471 KNRKGFTALHFAAQNSHLELVKYLVRRGVDITT 569 KN T L AAQ+ LE +++L + G DI T Sbjct: 267 KNVYSITPLFVAAQSGQLEALRFLAKHGADINT 299 Score = 53.1 bits (126), Expect = 5e-07 Identities = 31/117 (26%), Positives = 56/117 (47%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH++ D +E L S + +++ S TPL +AA +G ++ ++ L KH Sbjct: 242 LHESVSRNDLEVMEILV-SGGAKVEAKNVYSITPLFVAAQSGQLEALRFLAKHGADINTQ 300 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLV 545 ++ A + H +VV LL+ GA N+ G LH A++ + +V+ L+ Sbjct: 301 ASDSASALYEACKNEHEDVVEFLLSQGADANKANKDGLLPLHVASKKGNYRIVQMLL 357 Score = 48.1 bits (113), Expect = 2e-05 Identities = 32/125 (25%), Positives = 57/125 (45%) Frame = +3 Query: 189 LKLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXX 368 L LH+AA G ++ L + P ++ R T L+LA H+D + L + Sbjct: 140 LPLHEAAYYGKLGCLKVLQRAYPGTIDQRTLQEETALYLATCREHLDCLLSLLQAGAEPD 199 Query: 369 XXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVR 548 ++ A ++ + E VR L+ A + +G+TALH + + LE+++ LV Sbjct: 200 ISNKSRETPLYKACERKNAEAVRILVQYNADANHRCNRGWTALHESVSRNDLEVMEILVS 259 Query: 549 RGVDI 563 G + Sbjct: 260 GGAKV 264 Score = 46.2 bits (108), Expect = 6e-05 Identities = 33/122 (27%), Positives = 55/122 (45%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 L+KA +A AV L + A N R T LH + ++V++ L Sbjct: 209 LYKACERKNAEAVRILVQYNADA-NHRCNRGWTALHESVSRNDLEVMEILVSGGAKVEAK 267 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 + A+Q G LE +R L GA + + +AL+ A +N H ++V++L+ +G Sbjct: 268 NVYSITPLFVAAQSGQLEALRFLAKHGADINTQASDSASALYEACKNEHEDVVEFLLSQG 327 Query: 555 VD 560 D Sbjct: 328 AD 329 Score = 32.0 bits (71), Expect = 1.3 Identities = 35/137 (25%), Positives = 57/137 (41%), Gaps = 12/137 (8%) Frame = +3 Query: 189 LKLHKAARSGDAAAVESLCDSDPLALNSRDRLSRT---PLHLAAWAGHVDVVKCLCKHK- 356 L LH A++ G+ V+ L L + SR R+ R+ PLHLAA H V++ L + Sbjct: 339 LPLHVASKKGNYRIVQML-----LPVTSRTRVRRSGISPLHLAAERNHDAVLEALLAARF 393 Query: 357 --------XXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQ 512 ++FA ++ LL +GA NR + L A + Sbjct: 394 DVNTPLAPERARLYEDRRTSALYFAVVNNNVYATELLLLAGAD---PNRDVISPLLVAIR 450 Query: 513 NSHLELVKYLVRRGVDI 563 + L ++ L+ G +I Sbjct: 451 HGCLRTMQLLLDHGANI 467
>ILK2_HUMAN (P57043) Integrin-linked protein kinase 2 (EC 2.7.11.1) (ILK-2)| Length = 452 Score = 53.1 bits (126), Expect = 5e-07 Identities = 35/97 (36%), Positives = 49/97 (50%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH A R G +A VE L +N +R TPLHLAA GH D+V+ L ++K Sbjct: 38 LHWACREGRSAVVEMLIMRGA-RINVMNRGDDTPLHLAASHGHRDIVQKLLQYKADINAV 96 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKG 485 +H+A G +V +L+A+GA V N+ G Sbjct: 97 NEHGNVPLHYACFWGQDQVAEDLVANGALVSICNKYG 133 Score = 50.4 bits (119), Expect = 3e-06 Identities = 34/115 (29%), Positives = 49/115 (42%) Frame = +3 Query: 210 RSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXX 389 R G+A AV D+ LN D +PLH A G VV+ L Sbjct: 9 REGNAVAVRLWLDNTENDLNQGDDHGFSPLHWACREGRSAVVEMLIMRGARINVMNRGDD 68 Query: 390 XXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 +H A+ GH ++V++LL A + A N G LH+A ++ + LV G Sbjct: 69 TPLHLAASHGHRDIVQKLLQYKADINAVNEHGNVPLHYACFWGQDQVAEDLVANG 123 Score = 41.2 bits (95), Expect = 0.002 Identities = 20/56 (35%), Positives = 32/56 (57%) Frame = +3 Query: 396 IHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 +H+A ++G VV L+ GA + NR T LH AA + H ++V+ L++ DI Sbjct: 38 LHWACREGRSAVVEMLIMRGARINVMNRGDDTPLHLAASHGHRDIVQKLLQYKADI 93
>ILK1_HUMAN (Q13418) Integrin-linked protein kinase 1 (EC 2.7.11.1) (ILK-1) (59| kDa serine/threonine-protein kinase) (p59ILK) Length = 452 Score = 53.1 bits (126), Expect = 5e-07 Identities = 35/97 (36%), Positives = 49/97 (50%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH A R G +A VE L +N +R TPLHLAA GH D+V+ L ++K Sbjct: 38 LHWACREGRSAVVEMLIMRGA-RINVMNRGDDTPLHLAASHGHRDIVQKLLQYKADINAV 96 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKG 485 +H+A G +V +L+A+GA V N+ G Sbjct: 97 NEHGNVPLHYACFWGQDQVAEDLVANGALVSICNKYG 133 Score = 50.4 bits (119), Expect = 3e-06 Identities = 34/115 (29%), Positives = 49/115 (42%) Frame = +3 Query: 210 RSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXX 389 R G+A AV D+ LN D +PLH A G VV+ L Sbjct: 9 REGNAVAVRLWLDNTENDLNQGDDHGFSPLHWACREGRSAVVEMLIMRGARINVMNRGDD 68 Query: 390 XXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 +H A+ GH ++V++LL A + A N G LH+A ++ + LV G Sbjct: 69 TPLHLAASHGHRDIVQKLLQYKADINAVNEHGNVPLHYACFWGQDQVAEDLVANG 123 Score = 41.2 bits (95), Expect = 0.002 Identities = 20/56 (35%), Positives = 32/56 (57%) Frame = +3 Query: 396 IHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 +H+A ++G VV L+ GA + NR T LH AA + H ++V+ L++ DI Sbjct: 38 LHWACREGRSAVVEMLIMRGARINVMNRGDDTPLHLAASHGHRDIVQKLLQYKADI 93
>ZDH17_MOUSE (Q80TN5) Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger| DHHC domain-containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14) Length = 632 Score = 53.1 bits (126), Expect = 5e-07 Identities = 30/97 (30%), Positives = 51/97 (52%), Gaps = 1/97 (1%) Frame = +3 Query: 276 DRLSRTPLHLAAWAGHVDVVKC-LCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLAS 452 D+ + T LH AA +D+VK + K +H+A+++GHL +V +L+ Sbjct: 87 DKENVTLLHWAAINNRIDLVKYYISKGAIVDQLGGDLNSTPLHWATRQGHLSMVVQLMKY 146 Query: 453 GASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 GA + +G + +H AAQ H +V YL+ +G D+ Sbjct: 147 GADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQDV 183 Score = 50.4 bits (119), Expect = 3e-06 Identities = 28/80 (35%), Positives = 39/80 (48%) Frame = +3 Query: 282 LSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGAS 461 L+ TPLH A GH+ +V L K+ IH A+Q GH +V L+A G Sbjct: 123 LNSTPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQD 182 Query: 462 VKAKNRKGFTALHFAAQNSH 521 V ++ G T L +AA +H Sbjct: 183 VDMMDQNGMTPLMWAAYRTH 202 Score = 42.7 bits (99), Expect = 7e-04 Identities = 20/50 (40%), Positives = 33/50 (66%) Frame = +3 Query: 405 ASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 A+Q G E REL+ +G V+ +++ T LH+AA N+ ++LVKY + +G Sbjct: 64 ATQYGIYERCRELVEAGYDVRQPDKENVTLLHWAAINNRIDLVKYYISKG 113
>ZDH17_HUMAN (Q8IUH5) Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger| DHHC domain-containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14) (Huntingtin-interacting protein 3) (Huntingtin-interacting protein HYPH) (Putative NF-kappa-B-act Length = 632 Score = 53.1 bits (126), Expect = 5e-07 Identities = 30/97 (30%), Positives = 51/97 (52%), Gaps = 1/97 (1%) Frame = +3 Query: 276 DRLSRTPLHLAAWAGHVDVVKC-LCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLAS 452 D+ + T LH AA +D+VK + K +H+A+++GHL +V +L+ Sbjct: 87 DKENVTLLHWAAINNRIDLVKYYISKGAIVDQLGGDLNSTPLHWATRQGHLSMVVQLMKY 146 Query: 453 GASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 GA + +G + +H AAQ H +V YL+ +G D+ Sbjct: 147 GADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQDV 183 Score = 50.4 bits (119), Expect = 3e-06 Identities = 28/80 (35%), Positives = 39/80 (48%) Frame = +3 Query: 282 LSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGAS 461 L+ TPLH A GH+ +V L K+ IH A+Q GH +V L+A G Sbjct: 123 LNSTPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQD 182 Query: 462 VKAKNRKGFTALHFAAQNSH 521 V ++ G T L +AA +H Sbjct: 183 VDMMDQNGMTPLMWAAYRTH 202 Score = 42.7 bits (99), Expect = 7e-04 Identities = 20/50 (40%), Positives = 33/50 (66%) Frame = +3 Query: 405 ASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 A+Q G E REL+ +G V+ +++ T LH+AA N+ ++LVKY + +G Sbjct: 64 ATQYGIYERCRELVEAGYDVRQPDKENVTLLHWAAINNRIDLVKYYISKG 113
>ASB1_HUMAN (Q9Y576) Ankyrin repeat and SOCS box protein 1 (ASB-1)| Length = 335 Score = 53.1 bits (126), Expect = 5e-07 Identities = 36/133 (27%), Positives = 56/133 (42%), Gaps = 7/133 (5%) Frame = +3 Query: 186 DLKLHKAARSGDAAAVESLCDSDPLALNSRDR-------LSRTPLHLAAWAGHVDVVKCL 344 D +LH AA GD + SL + ++ L TPL +AA AGH V L Sbjct: 38 DTRLHDAAYVGDLQTLRSLLQEESYRSRINEKSVWCCGWLPCTPLRIAATAGHGSCVDFL 97 Query: 345 CKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHL 524 + ++ A GHLE + LL +GA T ++ A++ Sbjct: 98 IRKGAEVDLVDVKGQTALYVAVVNGHLESTQILLEAGADPNGSRHHRSTPVYHASRVGRA 157 Query: 525 ELVKYLVRRGVDI 563 +++K L+R G D+ Sbjct: 158 DILKALIRYGADV 170
>ANR10_HUMAN (Q9NXR5) Ankyrin repeat domain-containing protein 10| Length = 420 Score = 53.1 bits (126), Expect = 5e-07 Identities = 39/129 (30%), Positives = 59/129 (45%), Gaps = 6/129 (4%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLA-LNSRDRL-SRTPLHLAAWAGHVDVVKCLCK----HK 356 LH+A R GD A + SL P A L S D TP+H WA H ++CL + Sbjct: 26 LHRACRDGDLATLCSLLQQTPHAHLASEDSFYGWTPVH---WAAHFGKLECLVQLVRAGA 82 Query: 357 XXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVK 536 H A+ GH + + L+ +GA++ + +G T +H AA++ LE + Sbjct: 83 TLNVSTTRYAQTPAHIAAFGGHPQCLVWLIQAGANINKPDCEGETPIHKAARSGSLECIS 142 Query: 537 YLVRRGVDI 563 LV G + Sbjct: 143 ALVANGAHV 151
>AKR1_USTMA (Q4P6L3) Palmitoyltransferase AKR1 (EC 2.3.1.-) (Ankyrin| repeat-containing protein AKR1) Length = 844 Score = 53.1 bits (126), Expect = 5e-07 Identities = 33/122 (27%), Positives = 58/122 (47%), Gaps = 1/122 (0%) Frame = +3 Query: 189 LKLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXX 368 L +H AA+ GD A+ L DS ++ RD + TPLH AA + + L H Sbjct: 70 LTIHSAAQRGDLPAIMRLVDSGRATVHDRDDDNITPLHWAAINAQLATCRYLLDHGAQVD 129 Query: 369 XXXXXXXXX-IHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLV 545 + +A++ GH+ V+ L + GA + +GF ALH +S + + +++ Sbjct: 130 ALGGDLIASPLQWAARNGHVYVLELLCSRGADPTITDSQGFNALHLTVHSSAVMPLVFML 189 Query: 546 RR 551 ++ Sbjct: 190 QQ 191 Score = 39.3 bits (90), Expect = 0.008 Identities = 21/57 (36%), Positives = 33/57 (57%), Gaps = 1/57 (1%) Frame = +3 Query: 396 IHFASQKGHLEVVRELLASG-ASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 IH A+Q+G L + L+ SG A+V ++ T LH+AA N+ L +YL+ G + Sbjct: 72 IHSAAQRGDLPAIMRLVDSGRATVHDRDDDNITPLHWAAINAQLATCRYLLDHGAQV 128 Score = 33.5 bits (75), Expect = 0.44 Identities = 25/86 (29%), Positives = 34/86 (39%) Frame = +3 Query: 255 PLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVV 434 P L+S D T L AA+ G V L KH +H+A KG+ + Sbjct: 197 PEGLDSTDSQGHTALMWAAYQGDAISVDILLKHGADVHKRDGAGLTAMHWAVVKGNRLCI 256 Query: 435 RELLASGASVKAKNRKGFTALHFAAQ 512 R L + A + AK G T A + Sbjct: 257 RLLADAKADLLAKEDSGKTPRDMAIE 282
>ANKS3_RAT (Q5M9H0) Ankyrin repeat and SAM domain-containing protein 3| Length = 663 Score = 53.1 bits (126), Expect = 5e-07 Identities = 35/124 (28%), Positives = 55/124 (44%) Frame = +3 Query: 189 LKLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXX 368 L LH AA G V+ L LN ++ TPL A++ GH +V L + Sbjct: 37 LDLHTAASIGQYEVVKECVQRRELDLNKKNGGGWTPLMYASYIGHDTIVHLLLEAGVSVN 96 Query: 369 XXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVR 548 + AS G+ + LL GA ++ K+ +G+TAL H ++VK+L+ Sbjct: 97 VPTPEGQTPLMLASSCGNESIAYFLLQQGAELEMKDIQGWTALFHCTSAGHQQMVKFLLE 156 Query: 549 RGVD 560 G + Sbjct: 157 SGAN 160 Score = 41.2 bits (95), Expect = 0.002 Identities = 27/95 (28%), Positives = 43/95 (45%), Gaps = 1/95 (1%) Frame = +3 Query: 288 RTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVK 467 +TPL LA+ G+ + L + + + GH ++V+ LL SGA+ Sbjct: 103 QTPLMLASSCGNESIAYFLLQQGAELEMKDIQGWTALFHCTSAGHQQMVKFLLESGANAN 162 Query: 468 AKNR-KGFTALHFAAQNSHLELVKYLVRRGVDITT 569 + GFT L AA H +V+Y + GV + T Sbjct: 163 VREPVYGFTPLMEAAAAGHEIIVQYFLNHGVKVDT 197
>INVS_MOUSE (O89019) Inversin (Inversion of embryo turning protein)| (Nephrocystin-2) Length = 1062 Score = 53.1 bits (126), Expect = 5e-07 Identities = 30/119 (25%), Positives = 53/119 (44%) Frame = +3 Query: 204 AARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXX 383 A + D L + +N D+ T LH AA +GHV VK L + Sbjct: 330 AGKGNDDVLRTMLSLKSDIDINMSDKYGGTALHAAALSGHVSTVKLLLDNDAQVDATDVM 389 Query: 384 XXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVD 560 + A + GH +V++ L+ GA V ++ G + LH+AA + ++ + L+ ++ Sbjct: 390 KHTPLFRACEMGHRDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIENKIN 448 Score = 52.0 bits (123), Expect = 1e-06 Identities = 40/127 (31%), Positives = 62/127 (48%), Gaps = 7/127 (5%) Frame = +3 Query: 189 LKLHKAARSGDAAAVES---LCDSDPLA--LNSRDRLSRTPLHLAAWAGHVDVVKCLCKH 353 + LH AA D +AV + + D+ P LN +D RTPLH A G++ VV L + Sbjct: 184 IPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHFAVADGNLTVVDVLTSY 243 Query: 354 KX-XXXXXXXXXXXXIHFASQKGHLEVVRELLASGAS-VKAKNRKGFTALHFAAQNSHLE 527 + +H+A+ GH ++V LL S + +G T LH+AAQ++ E Sbjct: 244 ESCNITSYDNLFRTPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAE 303 Query: 528 LVKYLVR 548 VK ++ Sbjct: 304 TVKVFLQ 310 Score = 51.2 bits (121), Expect = 2e-06 Identities = 41/153 (26%), Positives = 62/153 (40%), Gaps = 36/153 (23%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLC-KHKXXXXX 371 LH A G+ V+ L + + S D L RTPLH AA GH +V L ++K Sbjct: 225 LHFAVADGNLTVVDVLTSYESCNITSYDNLFRTPLHWAALLGHAQIVHLLLERNKSGTIP 284 Query: 372 XXXXXXXXIHFASQ---------------------------------KGHLEVVRELLA- 449 +H+A+Q KG+ +V+R +L+ Sbjct: 285 SDSQGATPLHYAAQSNFAETVKVFLQHPSVKDDSDLEGRTSFMWAAGKGNDDVLRTMLSL 344 Query: 450 -SGASVKAKNRKGFTALHFAAQNSHLELVKYLV 545 S + ++ G TALH AA + H+ VK L+ Sbjct: 345 KSDIDINMSDKYGGTALHAAALSGHVSTVKLLL 377 Score = 51.2 bits (121), Expect = 2e-06 Identities = 31/119 (26%), Positives = 53/119 (44%) Frame = +3 Query: 192 KLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXX 371 ++H AA +GD A++ L + + DR RTPL A VD L K Sbjct: 17 QVHAAAVNGDKGALQRLIVGNSALRDKEDRFGRTPLMYCVLADRVDCADALLKAGADVNK 76 Query: 372 XXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVR 548 +H A+QKG+ ++ LL A+ K+ + T LH + ++ + + L++ Sbjct: 77 TDHSRRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLSTRHRSPKCLALLLK 135 Score = 50.8 bits (120), Expect = 3e-06 Identities = 33/122 (27%), Positives = 57/122 (46%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AA SG + V+ L D+D +++ D + TPL A GH DV++ L K Sbjct: 361 LHAAALSGHVSTVKLLLDNDA-QVDATDVMKHTPLFRACEMGHRDVIQTLIKGGARVDLV 419 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 +H+A+ G+ +V + L+ + + ++ G T L AA ++ + L+ Sbjct: 420 DQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENN 479 Query: 555 VD 560 D Sbjct: 480 AD 481 Score = 31.6 bits (70), Expect = 1.7 Identities = 25/102 (24%), Positives = 46/102 (45%), Gaps = 6/102 (5%) Frame = +3 Query: 255 PLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFAS---QKGHL 425 P ++++D+ +T LH +A+ + + K L KH +H+A+ + Sbjct: 139 PGEVDTQDKNKQTALHWSAYYNNPEHAKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSAV 198 Query: 426 EVVRELLASGASVKAKN---RKGFTALHFAAQNSHLELVKYL 542 VR +L + + N +G T LHFA + +L +V L Sbjct: 199 HTVRCILDAAPTESLLNWQDYEGRTPLHFAVADGNLTVVDVL 240
>ILK_CAVPO (P57044) Integrin-linked protein kinase (EC 2.7.11.1)| (Beta-integrin-linked kinase) Length = 451 Score = 53.1 bits (126), Expect = 5e-07 Identities = 35/97 (36%), Positives = 49/97 (50%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH A R G +A VE L +N +R TPLHLAA GH D+V+ L ++K Sbjct: 38 LHWACREGRSAVVEMLIMRGA-RINVMNRGDDTPLHLAASHGHRDIVQKLLQYKADINAV 96 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKG 485 +H+A G +V +L+A+GA V N+ G Sbjct: 97 NEHGNVPLHYACFWGQDQVAEDLVANGALVSICNKYG 133 Score = 50.4 bits (119), Expect = 3e-06 Identities = 34/115 (29%), Positives = 49/115 (42%) Frame = +3 Query: 210 RSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXX 389 R G+A AV D+ LN D +PLH A G VV+ L Sbjct: 9 REGNAVAVRLWLDNTENDLNQGDDHGFSPLHWACREGRSAVVEMLIMRGARINVMNRGDD 68 Query: 390 XXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 +H A+ GH ++V++LL A + A N G LH+A ++ + LV G Sbjct: 69 TPLHLAASHGHRDIVQKLLQYKADINAVNEHGNVPLHYACFWGQDQVAEDLVANG 123 Score = 41.2 bits (95), Expect = 0.002 Identities = 20/56 (35%), Positives = 32/56 (57%) Frame = +3 Query: 396 IHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 +H+A ++G VV L+ GA + NR T LH AA + H ++V+ L++ DI Sbjct: 38 LHWACREGRSAVVEMLIMRGARINVMNRGDDTPLHLAASHGHRDIVQKLLQYKADI 93
>NFKB1_CANFA (Q6F3J0) Nuclear factor NF-kappa-B p105 subunit [Contains: Nuclear| factor NF-kappa-B p50 subunit] Length = 972 Score = 52.8 bits (125), Expect = 7e-07 Identities = 44/132 (33%), Positives = 61/132 (46%), Gaps = 7/132 (5%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH A + A V+ L + L+ DRL + LHLAA G ++ L KHK Sbjct: 583 LHLAVITKQEAVVDDLLRAGA-DLSLLDRLGNSVLHLAAKEGQDKILSILLKHKKAALLM 641 Query: 375 ---XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRK-GFTALHFAAQNSHLELVKYL 542 IH A + + L+A+GA V A+ RK G TALH A ++ ++ L L Sbjct: 642 DHPNGEGLNAIHIAVMSNSMPCLLLLVAAGADVNAQERKSGRTALHLAVEHDNISLAGCL 701 Query: 543 VRRG---VDITT 569 + G VD TT Sbjct: 702 LLEGDAHVDSTT 713 Score = 39.3 bits (90), Expect = 0.008 Identities = 31/118 (26%), Positives = 52/118 (44%), Gaps = 3/118 (2%) Frame = +3 Query: 219 DAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXI 398 D V S SD + +N R+ L +TPLHLA VV L + + Sbjct: 558 DLLEVTSGLISDDI-INMRNDLYQTPLHLAVITKQEAVVDDLLRAGADLSLLDRLGNSVL 616 Query: 399 HFASQKGHLEVVRELL---ASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 H A+++G +++ LL + + N +G A+H A ++ + + LV G D+ Sbjct: 617 HLAAKEGQDKILSILLKHKKAALLMDHPNGEGLNAIHIAVMSNSMPCLLLLVAAGADV 674
>SAMD6_HUMAN (Q68DC2) Sterile alpha motif domain-containing protein 6 (Ankyrin| repeat domain-containing protein 14) Length = 871 Score = 52.8 bits (125), Expect = 7e-07 Identities = 31/100 (31%), Positives = 47/100 (47%) Frame = +3 Query: 255 PLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVV 434 P+ ++ D T L AA GH +V+ L + + A++ GH+ V Sbjct: 68 PVPVDCSDEAGNTALQFAAAGGHEPLVRFLLRRGASVNSRNHYGWSALMQAARFGHVSVA 127 Query: 435 RELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 LL GA V A+NR G + L A++ HL +VK L+ G Sbjct: 128 HLLLDHGADVNAQNRLGASVLTVASRGGHLGVVKLLLEAG 167 Score = 44.7 bits (104), Expect = 2e-04 Identities = 34/116 (29%), Positives = 54/116 (46%), Gaps = 3/116 (2%) Frame = +3 Query: 204 AARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLC-KHKXXXXXXXX 380 A + G+ V+ + D DP +N + TPL LAA G + +V+ L +H Sbjct: 299 ALKMGNFQLVKEIADEDPSHVNLVNGDGATPLMLAAVTGQLALVQLLVERHADVDKQDSV 358 Query: 381 XXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTA--LHFAAQNSHLELVKYL 542 + A+ G+ E+V+ LL GA V + + G+TA L + ELV+ L Sbjct: 359 HGWTALMQATYHGNKEIVKYLLNQGADVTLRAKNGYTAFDLVMLLNDPDTELVRLL 414 Score = 44.3 bits (103), Expect = 2e-04 Identities = 35/114 (30%), Positives = 48/114 (42%), Gaps = 14/114 (12%) Frame = +3 Query: 261 ALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRE 440 ++NSR+ + L AA GHV V L H + AS+ GHL VV+ Sbjct: 103 SVNSRNHYGWSALMQAARFGHVSVAHLLLDHGADVNAQNRLGASVLTVASRGGHLGVVKL 162 Query: 441 LLASGASVKAKNRKG--------------FTALHFAAQNSHLELVKYLVRRGVD 560 LL +GA V + G TAL A Q+ H +V+ L+ G D Sbjct: 163 LLEAGAFVDHHHPSGEQLGLGGSRDEPLDITALMAAIQHGHEAVVRLLMEWGAD 216 Score = 43.5 bits (101), Expect = 4e-04 Identities = 22/56 (39%), Positives = 34/56 (60%) Frame = +3 Query: 396 IHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 + FA+ GH +VR LL GASV ++N G++AL AA+ H+ + L+ G D+ Sbjct: 82 LQFAAAGGHEPLVRFLLRRGASVNSRNHYGWSALMQAARFGHVSVAHLLLDHGADV 137 Score = 33.1 bits (74), Expect = 0.57 Identities = 15/36 (41%), Positives = 21/36 (58%) Frame = +3 Query: 462 VKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDITT 569 V + G TAL FAA H LV++L+RRG + + Sbjct: 71 VDCSDEAGNTALQFAAAGGHEPLVRFLLRRGASVNS 106
>CTTB2_MICMU (Q2QL82) Cortactin-binding protein 2 (CortBP2)| Length = 1647 Score = 52.4 bits (124), Expect = 9e-07 Identities = 31/117 (26%), Positives = 57/117 (48%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 L+ AA++G V L +++ +N+ D+ TPL AA GH + V+ L + Sbjct: 734 LYSAAKNGHTDCVRLLLNAEA-QVNAADKNGFTPLCAAAAQGHFECVELLIAYDANINHA 792 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLV 545 ++ A + G+ E ++ LL +G K R G+T +H A +++ +K L+ Sbjct: 793 ADGGQTPLYLACKNGNKECIKLLLEAGTDRSVKTRDGWTPVHAAVDTGNVDSLKLLM 849 Score = 51.6 bits (122), Expect = 2e-06 Identities = 33/122 (27%), Positives = 54/122 (44%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 L +AA G+ + L + + L +N + L+ AA GH D V+ L + Sbjct: 700 LQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLNAEAQVNAA 759 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 + A+ +GH E V L+A A++ G T L+ A +N + E +K L+ G Sbjct: 760 DKNGFTPLCAAAAQGHFECVELLIAYDANINHAADGGQTPLYLACKNGNKECIKLLLEAG 819 Query: 555 VD 560 D Sbjct: 820 TD 821 Score = 40.8 bits (94), Expect = 0.003 Identities = 28/92 (30%), Positives = 43/92 (46%), Gaps = 1/92 (1%) Frame = +3 Query: 291 TPLHLAAWAGHVDVVKCLCKHKXXXXXXX-XXXXXXIHFASQKGHLEVVRELLASGASVK 467 T L AA G+V ++ L + ++ A++ GH + VR LL + A V Sbjct: 698 TLLQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLNAEAQVN 757 Query: 468 AKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 A ++ GFT L AA H E V+ L+ +I Sbjct: 758 AADKNGFTPLCAAAAQGHFECVELLIAYDANI 789
>POT15_HUMAN (Q6S5H4) Prostate, ovary, testis expressed protein on chromosome 15| Length = 581 Score = 52.4 bits (124), Expect = 9e-07 Identities = 39/124 (31%), Positives = 55/124 (44%) Frame = +3 Query: 192 KLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXX 371 KLH+AA G + + +N RD+ RT LHLA+ G+ +VV+ L + Sbjct: 142 KLHRAAWWGKVPRKDLIVMLRDTDMNKRDKQKRTALHLASANGNSEVVQLLLDRRCQLNV 201 Query: 372 XXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRR 551 + A Q E V LL GA ++ G TALH+A N + K L+ Sbjct: 202 LDNKKRTALIKAVQCQEDECVLMLLEHGADGNIQDEYGNTALHYAIYNEDKLMAKALLLY 261 Query: 552 GVDI 563 G DI Sbjct: 262 GADI 265 Score = 46.2 bits (108), Expect = 6e-05 Identities = 31/123 (25%), Positives = 54/123 (43%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH A+ +G++ V+ L D LN D RT L A + V L +H Sbjct: 177 LHLASANGNSEVVQLLLDRR-CQLNVLDNKKRTALIKAVQCQEDECVLMLLEHGADGNIQ 235 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 +H+A + + LL GA +++KN+ G T L ++VK+L+++ Sbjct: 236 DEYGNTALHYAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQQVVKFLIKKK 295 Query: 555 VDI 563 ++ Sbjct: 296 ANL 298 Score = 32.0 bits (71), Expect = 1.3 Identities = 22/86 (25%), Positives = 33/86 (38%) Frame = +3 Query: 264 LNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVREL 443 + S+++ TPL L VVK L K K + A G +V L Sbjct: 265 IESKNKCGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVNLL 324 Query: 444 LASGASVKAKNRKGFTALHFAAQNSH 521 L V +++ G TA +A + H Sbjct: 325 LEQNVDVSSQDLSGQTAREYAVSSHH 350
>CTTB2_CALMO (Q2QLB3) Cortactin-binding protein 2 (CortBP2)| Length = 1663 Score = 52.0 bits (123), Expect = 1e-06 Identities = 33/122 (27%), Positives = 54/122 (44%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 L +AA G+ + L + + L +N + L+ AA GH D V+ L + Sbjct: 714 LQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAA 773 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 + A+ +GH E V L+A A++ G T L+ A +N + E +K L+ G Sbjct: 774 DTNGFTPLCAAAAQGHFECVELLIAYDANINHAAGGGQTPLYLACKNGNKECIKLLLEAG 833 Query: 555 VD 560 D Sbjct: 834 TD 835 Score = 47.4 bits (111), Expect = 3e-05 Identities = 30/117 (25%), Positives = 54/117 (46%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 L+ AA++G V L ++ +N+ D TPL AA GH + V+ L + Sbjct: 748 LYSAAKNGHTDCVRLLLSAEA-QVNAADTNGFTPLCAAAAQGHFECVELLIAYDANINHA 806 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLV 545 ++ A + G+ E ++ LL +G K G+T +H A +++ +K L+ Sbjct: 807 AGGGQTPLYLACKNGNKECIKLLLEAGTDRCVKTTDGWTPVHAAVDTGNVDSLKLLM 863 Score = 40.8 bits (94), Expect = 0.003 Identities = 28/92 (30%), Positives = 43/92 (46%), Gaps = 1/92 (1%) Frame = +3 Query: 291 TPLHLAAWAGHVDVVKCLCKHKXXXXXXX-XXXXXXIHFASQKGHLEVVRELLASGASVK 467 T L AA G+V ++ L + ++ A++ GH + VR LL++ A V Sbjct: 712 TLLQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVN 771 Query: 468 AKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 A + GFT L AA H E V+ L+ +I Sbjct: 772 AADTNGFTPLCAAAAQGHFECVELLIAYDANI 803 Score = 31.2 bits (69), Expect = 2.2 Identities = 22/92 (23%), Positives = 36/92 (39%), Gaps = 4/92 (4%) Frame = +3 Query: 291 TPLHLAAWAGHVDVVKCLCKHKX----XXXXXXXXXXXXIHFASQKGHLEVVRELLASGA 458 TP+H A G+VD +K L H+ ++ E + + + Sbjct: 845 TPVHAAVDTGNVDSLKLLMYHRVPAHGNSFSEEESESGVFDLDGEEESPEGKSKPVVTAD 904 Query: 459 SVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 + NR+G+TA H AA ++ L R G Sbjct: 905 LINHANREGWTAAHIAAAKGFKNCLEILCRHG 936
>AKT6_ARATH (Q8GXE6) Potassium channel AKT6 (Shaker pollen inward rectifier| K(+) channel) (Potassium channel SPIK) Length = 888 Score = 52.0 bits (123), Expect = 1e-06 Identities = 37/125 (29%), Positives = 57/125 (45%), Gaps = 2/125 (1%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCD--SDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXX 368 LH AA G V L + +DP N RD PL A H ++ K L ++ Sbjct: 581 LHIAASKGSHYCVVLLLEHGADP---NIRDSEGNVPLWEAIIGRHREIAKLLAENGAKLS 637 Query: 369 XXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVR 548 + A +K L+ +++++ G V + G TALH A HLE+VK+L+ Sbjct: 638 LDSVSYFSGL--AVEKNCLDALKDIIKYGGDVTLPDGNGTTALHRAVSEGHLEIVKFLLD 695 Query: 549 RGVDI 563 +G D+ Sbjct: 696 QGADL 700 Score = 32.3 bits (72), Expect = 0.97 Identities = 18/53 (33%), Positives = 27/53 (50%) Frame = +3 Query: 402 FASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVD 560 FA+ +G ++ +LL G+S ++ G TALH AA V L+ G D Sbjct: 550 FAAARGDDLLLHQLLRRGSSPNEMDKDGRTALHIAASKGSHYCVVLLLEHGAD 602 Score = 31.6 bits (70), Expect = 1.7 Identities = 20/76 (26%), Positives = 33/76 (43%) Frame = +3 Query: 303 LAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRK 482 LA +D +K + K+ +H A +GHLE+V+ LL GA + + Sbjct: 647 LAVEKNCLDALKDIIKYGGDVTLPDGNGTTALHRAVSEGHLEIVKFLLDQGADLDWPDSY 706 Query: 483 GFTALHFAAQNSHLEL 530 G+T A + E+ Sbjct: 707 GWTPRGLADHQGNEEI 722
>AKR_ARATH (Q05753) Ankyrin repeat protein, chloroplast precursor (AKRP)| Length = 435 Score = 52.0 bits (123), Expect = 1e-06 Identities = 36/125 (28%), Positives = 55/125 (44%) Frame = +3 Query: 189 LKLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXX 368 L LH A G+ V+SL + L +N+ D T LH A + L + Sbjct: 262 LPLHTLAACGEFYLVDSLLKHN-LDINATDVGGLTVLHRAIIGKKQAITNYLLRESANPF 320 Query: 369 XXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVR 548 +H+A Q ++ LL A + A++R G+T LH A Q ++VK L+ Sbjct: 321 VLDDEGATLMHYAVQTASAPTIKLLLLYNADINAQDRDGWTPLHVAVQARRSDIVKLLLI 380 Query: 549 RGVDI 563 +G DI Sbjct: 381 KGADI 385
>AKR1_YARLI (Q6C520) Palmitoyltransferase AKR1 (EC 2.3.1.-) (Ankyrin| repeat-containing protein AKR1) Length = 702 Score = 52.0 bits (123), Expect = 1e-06 Identities = 32/121 (26%), Positives = 59/121 (48%), Gaps = 1/121 (0%) Frame = +3 Query: 204 AARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXX 383 AAR G+ A V+ LC+S ++ T LH AA + + L + Sbjct: 57 AARDGNTAEVKRLCESGSYSVLDTAEDGVTALHWAAVNNRISTCQYLVEQGAVVDAKGGQ 116 Query: 384 XXXX-IHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVD 560 +H+A ++G + +V L+ +GA + +G+ ALH A +S++ L+ YL+ +G+ Sbjct: 117 LNGTPLHWACRRGLVYIVHYLIQNGADPLRSDVQGYNALHLATHSSNVMLLVYLLHQGLP 176 Query: 561 I 563 + Sbjct: 177 V 177 Score = 45.1 bits (105), Expect = 1e-04 Identities = 33/123 (26%), Positives = 54/123 (43%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AA + + + L + + +L+ TPLH A G V +V L ++ Sbjct: 88 LHWAAVNNRISTCQYLVEQGAVVDAKGGQLNGTPLHWACRRGLVYIVHYLIQNGADPLRS 147 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 +H A+ ++ ++ LL G V ++ G TALH+AA V L+R G Sbjct: 148 DVQGYNALHLATHSSNVMLLVYLLHQGLPVDCQDPNGRTALHWAAYQGDALSVDVLLRWG 207 Query: 555 VDI 563 D+ Sbjct: 208 SDV 210 Score = 37.4 bits (85), Expect = 0.030 Identities = 33/123 (26%), Positives = 49/123 (39%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH A R G V L + L S D LHLA + +V ++ L Sbjct: 122 LHWACRRGLVYIVHYLIQNGADPLRS-DVQGYNALHLATHSSNVMLLVYLLHQGLPVDCQ 180 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 +H+A+ +G V LL G+ VK + +GF LH+ N + L+ G Sbjct: 181 DPNGRTALHWAAYQGDALSVDVLLRWGSDVKITDTQGFLPLHWGIVNGSRNSLARLIEEG 240 Query: 555 VDI 563 D+ Sbjct: 241 SDM 243
>TRPA1_DROME (Q7Z020) Transient receptor potential cation channel subfamily A| member 1 (Ankyrin-like with transmembrane domains protein 1) (dANKTM1) Length = 1197 Score = 52.0 bits (123), Expect = 1e-06 Identities = 30/102 (29%), Positives = 49/102 (48%), Gaps = 3/102 (2%) Frame = +3 Query: 258 LALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVR 437 L LN +D + +PLH A+ GH+ ++ L + +HFA++ G VR Sbjct: 435 LLLNEKDSMGCSPLHYASRDGHIRSLENLIRLGACINLKNNNNESPLHFAARYGRYNTVR 494 Query: 438 ELLASGAS---VKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 +LL S + + G T LH ++Q H +V+ L+ RG Sbjct: 495 QLLDSEKGSFIINESDGAGMTPLHISSQQGHTRVVQLLLNRG 536 Score = 45.1 bits (105), Expect = 1e-04 Identities = 37/124 (29%), Positives = 55/124 (44%), Gaps = 4/124 (3%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDP--LALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXX 368 LH AAR G V L DS+ +N D TPLH+++ GH VV+ L ++ Sbjct: 481 LHFAARYGRYNTVRQLLDSEKGSFIINESDGAGMTPLHISSQQGHTRVVQLLL-NRGALL 539 Query: 369 XXXXXXXXXIHFASQKGHLEVVRELLASGAS--VKAKNRKGFTALHFAAQNSHLELVKYL 542 + A+ G+ E + ELL S S + ++ G TALH A + + L Sbjct: 540 HRDHTGRNPLQLAAMSGYTETI-ELLHSVHSHLLDQVDKDGNTALHLATMENKPHAISVL 598 Query: 543 VRRG 554 + G Sbjct: 599 MSMG 602 Score = 41.6 bits (96), Expect = 0.002 Identities = 34/126 (26%), Positives = 52/126 (41%) Frame = +3 Query: 186 DLKLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXX 365 ++ LH A GD AVE LC ++++ TP+HLA G +D+VK + + + Sbjct: 267 NVPLHSAVHGGDIKAVE-LCLKSGAKISTQQHDLSTPVHLACAQGAIDIVKLMFEMQ--- 322 Query: 366 XXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLV 545 + + L S V+ T LH A+ H ++V YLV Sbjct: 323 --------------------PMEKRLCLSCTDVQK-----MTPLHCASMFDHPDIVSYLV 357 Query: 546 RRGVDI 563 G DI Sbjct: 358 AEGADI 363 Score = 33.9 bits (76), Expect = 0.33 Identities = 22/95 (23%), Positives = 39/95 (41%), Gaps = 2/95 (2%) Frame = +3 Query: 267 NSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVREL- 443 N++D TPLH+A + D + L +H A++ ++ +R + Sbjct: 117 NAKDNAGNTPLHIAVESDAYDALDYLLSIPVDTGVLNEKKQAPVHLATELNKVKSLRVMG 176 Query: 444 -LASGASVKAKNRKGFTALHFAAQNSHLELVKYLV 545 + ++ G TALH AA H E + L+ Sbjct: 177 QYRNVIDIQQGGEHGRTALHLAAIYDHEECARILI 211 Score = 33.5 bits (75), Expect = 0.44 Identities = 22/91 (24%), Positives = 39/91 (42%), Gaps = 1/91 (1%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCL-CKHKXXXXX 371 LH +++ G V+ L + AL RD R PL LAA +G+ + ++ L H Sbjct: 517 LHISSQQGHTRVVQLLLNRG--ALLHRDHTGRNPLQLAAMSGYTETIELLHSVHSHLLDQ 574 Query: 372 XXXXXXXXIHFASQKGHLEVVRELLASGASV 464 +H A+ + + L++ G + Sbjct: 575 VDKDGNTALHLATMENKPHAISVLMSMGCKL 605 Score = 31.2 bits (69), Expect = 2.2 Identities = 26/108 (24%), Positives = 46/108 (42%), Gaps = 8/108 (7%) Frame = +3 Query: 264 LNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKG-HLEVVRE 440 +N+ D+ R+PL LAA V L + +HF G L E Sbjct: 363 INALDKEHRSPLLLAASRSGWKTVHLLIRLGACISVKDAAARNVLHFVIMNGGRLTDFAE 422 Query: 441 LLASGAS-------VKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 +A+ + + K+ G + LH+A+++ H+ ++ L+R G I Sbjct: 423 QVANCQTQAQLKLLLNEKDSMGCSPLHYASRDGHIRSLENLIRLGACI 470 Score = 29.6 bits (65), Expect = 6.3 Identities = 14/54 (25%), Positives = 26/54 (48%) Frame = +3 Query: 399 HFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVD 560 H A+ + + ++R + AK+ G T LH A ++ + + YL+ VD Sbjct: 95 HQAAARNRVNILRYIRDQNGDFNAKDNAGNTPLHIAVESDAYDALDYLLSIPVD 148 Score = 29.3 bits (64), Expect = 8.2 Identities = 24/123 (19%), Positives = 49/123 (39%), Gaps = 2/123 (1%) Frame = +3 Query: 201 KAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXX 380 +AA SG+ + L +D + +D RT H AA V++++ + Sbjct: 62 EAAESGNLDDFKRLFMADNSRIALKDAKGRTAAHQAAARNRVNILRYIRDQNGDFNAKDN 121 Query: 381 XXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYL--VRRG 554 +H A + + + LL+ N K +H A + + ++ ++ + R Sbjct: 122 AGNTPLHIAVESDAYDALDYLLSIPVDTGVLNEKKQAPVHLATELNKVKSLRVMGQYRNV 181 Query: 555 VDI 563 +DI Sbjct: 182 IDI 184
>NOTC4_MOUSE (P31695) Neurogenic locus notch homolog protein 4 precursor (Notch 4)| [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain] Length = 1964 Score = 51.6 bits (122), Expect = 2e-06 Identities = 37/123 (30%), Positives = 59/123 (47%), Gaps = 1/123 (0%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCL-CKHKXXXXX 371 LH AAR A L ++ N DR RTPLH A A +V + L + Sbjct: 1633 LHLAARFSRPTAARRLLEAGANP-NQPDRAGRTPLHTAVAADAREVCQLLLASRQTSVDA 1691 Query: 372 XXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRR 551 + A++ ++V EL+A+ A V A++++G TALH+AA ++ + L++ Sbjct: 1692 RTEDGTTPLMLAARLAVEDLVEELIAARADVGARDKRGKTALHWAAAVNNARAARSLLQA 1751 Query: 552 GVD 560 G D Sbjct: 1752 GAD 1754 Score = 41.6 bits (96), Expect = 0.002 Identities = 30/120 (25%), Positives = 52/120 (43%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH A + + L S ++++R TPL LAA D+V+ L + Sbjct: 1666 LHTAVAADAREVCQLLLASRQTSVDARTEDGTTPLMLAARLAVEDLVEELIAARADVGAR 1725 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 +H+A+ + R LL +GA A++ + T L AA+ +E+ + L+ G Sbjct: 1726 DKRGKTALHWAAAVNNARAARSLLQAGADKDAQDSREQTPLFLAAREGAVEVAQLLLELG 1785
>AKR1_CANGA (Q6FJ70) Palmitoyltransferase AKR1 (EC 2.3.1.-) (Ankyrin| repeat-containing protein AKR1) Length = 763 Score = 51.6 bits (122), Expect = 2e-06 Identities = 35/120 (29%), Positives = 57/120 (47%), Gaps = 2/120 (1%) Frame = +3 Query: 192 KLHKAARSGDAAAVESLCDSDPLALNS-RDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXX 368 K H A + GD V + + ++S DR T LH AA ++VV L + Sbjct: 61 KYHNACQRGDLEVVREMIHGGQVNVSSDADREGVTGLHWAAINNRLNVVDFLVREGANVE 120 Query: 369 XXXXXXXXX-IHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLV 545 +H+A++ G + VV LL GAS +++GF LH + +S++ LV Y++ Sbjct: 121 SKAGALEATPLHWAARYGFVYVVDYLLQHGASATTTDKQGFNLLHLSVNSSNIMLVVYVL 180 Score = 47.8 bits (112), Expect = 2e-05 Identities = 26/57 (45%), Positives = 39/57 (68%), Gaps = 2/57 (3%) Frame = +3 Query: 399 HFASQKGHLEVVRELLASG-ASVKAK-NRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 H A Q+G LEVVRE++ G +V + +R+G T LH+AA N+ L +V +LVR G ++ Sbjct: 63 HNACQRGDLEVVREMIHGGQVNVSSDADREGVTGLHWAAINNRLNVVDFLVREGANV 119 Score = 39.7 bits (91), Expect = 0.006 Identities = 39/160 (24%), Positives = 54/160 (33%), Gaps = 38/160 (23%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AA + V+ L + L TPLH AA G V VV L +H Sbjct: 97 LHWAAINNRLNVVDFLVREGANVESKAGALEATPLHWAARYGFVYVVDYLLQHGASATTT 156 Query: 375 XXXXXXXIH----------------FASQKGHLEV----------------------VRE 440 +H F KG +++ V Sbjct: 157 DKQGFNLLHLSVNSSNIMLVVYVLFFVVSKGIIDIDYVDPKGRTALLWAAYQGDSLTVAA 216 Query: 441 LLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVD 560 L+ ASVK + GFT LH+ ++KYL++ G D Sbjct: 217 LIKFNASVKIADEGGFTPLHWGTVKGQPHVLKYLIQDGAD 256 Score = 35.8 bits (81), Expect = 0.088 Identities = 21/59 (35%), Positives = 34/59 (57%), Gaps = 1/59 (1%) Frame = +3 Query: 396 IHFASQKGHLEVVRELLASGASVKAK-NRKGFTALHFAAQNSHLELVKYLVRRGVDITT 569 +H+A+ L VV L+ GA+V++K T LH+AA+ + +V YL++ G TT Sbjct: 97 LHWAAINNRLNVVDFLVREGANVESKAGALEATPLHWAARYGFVYVVDYLLQHGASATT 155
>ANKH_CHRVI (Q06527) Ankyrin homolog precursor| Length = 323 Score = 51.6 bits (122), Expect = 2e-06 Identities = 36/119 (30%), Positives = 53/119 (44%) Frame = +3 Query: 207 ARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXX 386 A GD +L S +N+R TPL AA AGH+ + L + Sbjct: 72 AVEGDDLETVALLLSRGADVNARTVAGCTPLTFAAEAGHIGISALLLERGAHVHDRTRSG 131 Query: 387 XXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 + AS+ G ++V +LL GA KA +R+G TAL AA ++ L+ G D+ Sbjct: 132 WDALMIASRHGITDMVEQLLFKGADPKAADREGRTALMQAASKGETGVLPLLIEGGADL 190 Score = 50.1 bits (118), Expect = 4e-06 Identities = 36/120 (30%), Positives = 51/120 (42%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 L +AA G+ + L + L +RD+ T L +AA G V+ L Sbjct: 168 LMQAASKGETGVLPLLIEGGA-DLEARDKQGATALLIAADQGQAGAVETLAGLGAQLDAV 226 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 + A GH+ +V LLA GA ++RKG TAL A H EL+ L+ G Sbjct: 227 DALGSTALILAVGHGHVAMVERLLAMGADPNRQDRKGTTALMEAVATDHAELIDRLIAAG 286 Score = 42.0 bits (97), Expect = 0.001 Identities = 23/49 (46%), Positives = 27/49 (55%) Frame = +3 Query: 417 GHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 G E ELL GA V A N+ G TAL FA + LE V L+ RG D+ Sbjct: 43 GDTETAAELLDQGAHVDAPNQFGKTALMFAVEGDDLETVALLLSRGADV 91 Score = 41.6 bits (96), Expect = 0.002 Identities = 36/121 (29%), Positives = 50/121 (41%), Gaps = 2/121 (1%) Frame = +3 Query: 204 AARSGDAAAVESLC--DSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXX 377 A+R G VE L +DP A DR RT L AA G V+ L + Sbjct: 138 ASRHGITDMVEQLLFKGADPKAA---DREGRTALMQAASKGETGVLPLLIEGGADLEARD 194 Query: 378 XXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGV 557 + A+ +G V L GA + A + G TAL A + H+ +V+ L+ G Sbjct: 195 KQGATALLIAADQGQAGAVETLAGLGAQLDAVDALGSTALILAVGHGHVAMVERLLAMGA 254 Query: 558 D 560 D Sbjct: 255 D 255
>YR896_MIMIV (Q5UQY9) Putative ankyrin repeat protein R896| Length = 332 Score = 51.6 bits (122), Expect = 2e-06 Identities = 40/122 (32%), Positives = 61/122 (50%) Frame = +3 Query: 204 AARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXX 383 AA+ G+ V+ L +S + S+D + + LA+ GH+DVV+ L K Sbjct: 167 AAQKGNLEIVKFLVESGA-NVKSQDNCA---VRLASEFGHLDVVEYLYK---SGANVKAD 219 Query: 384 XXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 I +A + GHL V+ L + GA +KA + AA HL ++KYLV RG +I Sbjct: 220 GNYAITWACKNGHLPVIEFLTSVGADIKAAQN---LPIKMAAIGGHLNVIKYLVDRGANI 276 Query: 564 TT 569 +T Sbjct: 277 ST 278 Score = 47.4 bits (111), Expect = 3e-05 Identities = 30/87 (34%), Positives = 47/87 (54%) Frame = +3 Query: 303 LAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRK 482 +AA G++++VK L + + AS+ GHL+VV L SGA+VKA Sbjct: 166 IAAQKGNLEIVKFLVE---SGANVKSQDNCAVRLASEFGHLDVVEYLYKSGANVKA---D 219 Query: 483 GFTALHFAAQNSHLELVKYLVRRGVDI 563 G A+ +A +N HL ++++L G DI Sbjct: 220 GNYAITWACKNGHLPVIEFLTSVGADI 246 Score = 36.6 bits (83), Expect = 0.051 Identities = 20/56 (35%), Positives = 30/56 (53%) Frame = +3 Query: 396 IHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 I A+ GHL V++ L+ GA++ N F + A +N H +L +Y V G DI Sbjct: 254 IKMAAIGGHLNVIKYLVDRGANISTDNDYVF---NIACRNGHTDLAEYAVSLGADI 306
>Y3287_PSEAE (Q9HYV6) Hypothetical ANK-repeat protein PA3287| Length = 171 Score = 51.2 bits (121), Expect = 2e-06 Identities = 38/121 (31%), Positives = 56/121 (46%) Frame = +3 Query: 192 KLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXX 371 +L AR G++ +E L L N R+ + L LA++ GH D V+ L +K Sbjct: 19 QLFDLARQGNSQRLEQLLQQG-LPPNLRNHKGDSLLMLASYHGHADTVRLLLAYKADPDL 77 Query: 372 XXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRR 551 + A+ KG L +V LLA GA V+ + G TAL AA + E+ L+ Sbjct: 78 RNLAGQTPLAGAAFKGDLAMVELLLAGGADVEGASADGKTALMMAAMFNQAEVAASLLAH 137 Query: 552 G 554 G Sbjct: 138 G 138 Score = 33.9 bits (76), Expect = 0.33 Identities = 21/53 (39%), Positives = 27/53 (50%) Frame = +3 Query: 405 ASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 AS GH + VR LLA A +N G T L AA L +V+ L+ G D+ Sbjct: 56 ASYHGHADTVRLLLAYKADPDLRNLAGQTPLAGAAFKGDLAMVELLLAGGADV 108
>ANR21_HUMAN (Q86YR6) Ankyrin repeat domain-containing protein 21 (Protein POTE)| (Prostate, ovary, testis expressed protein) Length = 584 Score = 51.2 bits (121), Expect = 2e-06 Identities = 39/124 (31%), Positives = 54/124 (43%) Frame = +3 Query: 192 KLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXX 371 KLH+AA G + + +N RD+ RT LHLA+ G+ +VV+ L + Sbjct: 142 KLHRAAWWGKVPRKDLIVMLRDTDMNKRDKEKRTALHLASANGNSEVVQLLLDRRCQLNV 201 Query: 372 XXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRR 551 + A Q E V LL GA + G TALH+A N + K L+ Sbjct: 202 LDNKKRTALIKAIQCQEDECVLMLLEHGADRNIPDEYGNTALHYAIYNEDKLMAKALLLY 261 Query: 552 GVDI 563 G DI Sbjct: 262 GADI 265 Score = 45.4 bits (106), Expect = 1e-04 Identities = 31/123 (25%), Positives = 54/123 (43%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH A+ +G++ V+ L D LN D RT L A + V L +H Sbjct: 177 LHLASANGNSEVVQLLLDRR-CQLNVLDNKKRTALIKAIQCQEDECVLMLLEHGADRNIP 235 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 +H+A + + LL GA +++KN+ G T L ++VK+L+++ Sbjct: 236 DEYGNTALHYAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQQVVKFLIKKK 295 Query: 555 VDI 563 ++ Sbjct: 296 ANL 298 Score = 31.6 bits (70), Expect = 1.7 Identities = 22/86 (25%), Positives = 33/86 (38%) Frame = +3 Query: 264 LNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVREL 443 + S+++ TPL L VVK L K K + A G +V L Sbjct: 265 IESKNKCGLTPLLLGVHEQKQQVVKFLIKKKANLNVLDRYGRTALILAVCCGSASIVNLL 324 Query: 444 LASGASVKAKNRKGFTALHFAAQNSH 521 L V +++ G TA +A + H Sbjct: 325 LEQNVDVSSQDLSGQTAREYAVSSHH 350
>V227_FOWPV (Q9J508) Putative ankyrin repeat protein FPV227| Length = 361 Score = 50.8 bits (120), Expect = 3e-06 Identities = 30/100 (30%), Positives = 48/100 (48%) Frame = +3 Query: 267 NSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELL 446 N D R+P+H A G+ ++VK L +HK I + + +E+V+ LL Sbjct: 53 NFYDEYMRSPIHYAVEKGNTEMVKALLEHKADPNIFDDNFDYPITNSIIENKVEIVKILL 112 Query: 447 ASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDIT 566 GA N F LH A +N H+++ K L+ G+ +T Sbjct: 113 QYGADKTMINE--FDLLHDAIKNKHIDMAKILIDNGISLT 150
>YR844_MIMIV (Q5UP15) Putative ankyrin repeat protein R844| Length = 214 Score = 50.8 bits (120), Expect = 3e-06 Identities = 32/90 (35%), Positives = 46/90 (51%) Frame = +3 Query: 294 PLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAK 473 PL LA+ GH+D +K L ++ + AS GH+ VV+ L+ GA V + Sbjct: 115 PLRLASQNGHIDTIKYLIENSVDVRANNDCA---LRMASLFGHINVVKYLVDMGADVTSD 171 Query: 474 NRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 N F +H A++ LEL KYL +G DI Sbjct: 172 NN--FAIIH-TARSGRLELAKYLAEKGADI 198 Score = 43.9 bits (102), Expect = 3e-04 Identities = 21/58 (36%), Positives = 34/58 (58%) Frame = +3 Query: 396 IHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDITT 569 + ASQ GH++ ++ L+ + V+A N AL A+ H+ +VKYLV G D+T+ Sbjct: 116 LRLASQNGHIDTIKYLIENSVDVRANND---CALRMASLFGHINVVKYLVDMGADVTS 170 Score = 43.5 bits (101), Expect = 4e-04 Identities = 19/49 (38%), Positives = 30/49 (61%) Frame = +3 Query: 417 GHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 GHLE+ + ++ GA+VK N L A+QN H++ +KYL+ VD+ Sbjct: 93 GHLEMTKYFVSQGANVKTDNNM---PLRLASQNGHIDTIKYLIENSVDV 138
>ASB1_MOUSE (Q9WV74) Ankyrin repeat and SOCS box protein 1 (ASB-1)| Length = 336 Score = 50.8 bits (120), Expect = 3e-06 Identities = 35/133 (26%), Positives = 56/133 (42%), Gaps = 7/133 (5%) Frame = +3 Query: 186 DLKLHKAARSGDAAAVESLCDSDPLALNSRDR-------LSRTPLHLAAWAGHVDVVKCL 344 D +LH AA GD + +L + ++ L TPL +AA AGH + V L Sbjct: 39 DTRLHDAAYVGDLQTLRNLLQEESYRSRINEKSVWCCGWLPCTPLRIAATAGHGNCVDFL 98 Query: 345 CKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHL 524 + ++ A GHLE LL +GA T ++ A++ Sbjct: 99 IRKGAEVDLVDVKGQTALYVAVVNGHLESTEILLEAGADPNGSRHHRSTPVYHASRVGRD 158 Query: 525 ELVKYLVRRGVDI 563 +++K L+R G D+ Sbjct: 159 DILKALIRYGADV 171
>CTTB2_CALJA (Q2QLF8) Cortactin-binding protein 2 (CortBP2)| Length = 1662 Score = 50.8 bits (120), Expect = 3e-06 Identities = 31/117 (26%), Positives = 55/117 (47%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 L+ AA++G V L ++ +N+ D+ TPL AA GH + V+ L + Sbjct: 747 LYSAAKNGHTDCVRLLLSAEA-QVNAADKNGFTPLCAAAAQGHFECVELLIAYDANINHA 805 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLV 545 ++ A + G+ E +R LL +G K G+T +H A +++ +K L+ Sbjct: 806 ADGGQTPLYLACKNGNKECIRLLLEAGTDRSVKTTDGWTPVHAAVDTGNVDSLKLLM 862 Score = 50.4 bits (119), Expect = 3e-06 Identities = 32/122 (26%), Positives = 54/122 (44%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 L +AA G+ + L + + L +N + L+ AA GH D V+ L + Sbjct: 713 LQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAA 772 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 + A+ +GH E V L+A A++ G T L+ A +N + E ++ L+ G Sbjct: 773 DKNGFTPLCAAAAQGHFECVELLIAYDANINHAADGGQTPLYLACKNGNKECIRLLLEAG 832 Query: 555 VD 560 D Sbjct: 833 TD 834 Score = 42.0 bits (97), Expect = 0.001 Identities = 28/92 (30%), Positives = 44/92 (47%), Gaps = 1/92 (1%) Frame = +3 Query: 291 TPLHLAAWAGHVDVVKCLCKHKXXXXXXX-XXXXXXIHFASQKGHLEVVRELLASGASVK 467 T L AA G+V ++ L + ++ A++ GH + VR LL++ A V Sbjct: 711 TLLQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVN 770 Query: 468 AKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 A ++ GFT L AA H E V+ L+ +I Sbjct: 771 AADKNGFTPLCAAAAQGHFECVELLIAYDANI 802
>V219_FOWPV (Q9J516) Putative ankyrin repeat protein FPV219| Length = 434 Score = 50.8 bits (120), Expect = 3e-06 Identities = 31/99 (31%), Positives = 51/99 (51%) Frame = +3 Query: 264 LNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVREL 443 +N+ D L P+HLA G++D++K L H +H + + EVV L Sbjct: 159 VNTFDPLYGYPIHLAIRYGNIDIIKELLYH--GVIESYSLYPSLLHQSIMCNNKEVVLLL 216 Query: 444 LASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVD 560 ++ G V AK+ +G T +H A Q + + +VK L+ +G D Sbjct: 217 ISMGFDVNAKDNEGNTPMHLAVQKNLVGIVKILLDKGAD 255 Score = 40.8 bits (94), Expect = 0.003 Identities = 19/55 (34%), Positives = 32/55 (58%) Frame = +3 Query: 396 IHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVD 560 +H A +G+ E+V +L GA V N + + LH A +N ++E+V+ L+ G D Sbjct: 38 LHHAVSRGYKEIVISMLEHGADVNLCNDEVCSPLHIAIKNDNVEMVQLLIDNGAD 92
>SHAN1_HUMAN (Q9Y566) SH3 and multiple ankyrin repeat domains protein 1 (Shank1)| (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP) Length = 2161 Score = 50.4 bits (119), Expect = 3e-06 Identities = 40/123 (32%), Positives = 55/123 (44%), Gaps = 1/123 (0%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPL-HLAAWAGHVDVVKCLCKHKXXXXX 371 LHKAA + A+ +L D + N +DR TPL H A G + L ++ Sbjct: 251 LHKAACARHCLALTALLDLGG-SPNYKDRRGLTPLFHTAMVGGDPRCCELLLFNRAQLGI 309 Query: 372 XXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRR 551 IH A Q+GH + + LL GA A+N G TALH A + + L+ R Sbjct: 310 ADENGWQEIHQACQRGHSQHLEHLLFYGAEPGAQNASGNTALHICALYNKETCARILLYR 369 Query: 552 GVD 560 G D Sbjct: 370 GAD 372 Score = 33.5 bits (75), Expect = 0.44 Identities = 17/39 (43%), Positives = 22/39 (56%) Frame = +3 Query: 405 ASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSH 521 A +G +EV+R L GA + + R G TALH AA H Sbjct: 221 AQTEGSVEVIRTLCLGGAHIDFRARDGMTALHKAACARH 259
>CTTB2_HUMAN (Q8WZ74) Cortactin-binding protein 2 (CortBP2)| Length = 1663 Score = 50.4 bits (119), Expect = 3e-06 Identities = 30/117 (25%), Positives = 56/117 (47%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 L+ AA++G V L ++ +N+ D+ TPL AA GH + V+ L + Sbjct: 748 LYSAAKNGHTDCVRLLLSAEA-QVNAADKNGFTPLCAAAAQGHFECVELLISYDANINHA 806 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLV 545 ++ A + G+ E ++ LL +G + K G+T +H A +++ +K L+ Sbjct: 807 ADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLM 863 Score = 48.5 bits (114), Expect = 1e-05 Identities = 31/122 (25%), Positives = 54/122 (44%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 L +AA G+ + L + + L +N + L+ AA GH D V+ L + Sbjct: 714 LQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAA 773 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 + A+ +GH E V L++ A++ G T L+ A +N + E +K L+ G Sbjct: 774 DKNGFTPLCAAAAQGHFECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLLLEAG 833 Query: 555 VD 560 + Sbjct: 834 TN 835 Score = 42.0 bits (97), Expect = 0.001 Identities = 28/92 (30%), Positives = 44/92 (47%), Gaps = 1/92 (1%) Frame = +3 Query: 291 TPLHLAAWAGHVDVVKCLCKHKXXXXXXX-XXXXXXIHFASQKGHLEVVRELLASGASVK 467 T L AA G+V ++ L + ++ A++ GH + VR LL++ A V Sbjct: 712 TLLQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVN 771 Query: 468 AKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 A ++ GFT L AA H E V+ L+ +I Sbjct: 772 AADKNGFTPLCAAAAQGHFECVELLISYDANI 803 Score = 31.2 bits (69), Expect = 2.2 Identities = 22/92 (23%), Positives = 35/92 (38%), Gaps = 4/92 (4%) Frame = +3 Query: 291 TPLHLAAWAGHVDVVKCLCKHKXXXXXXXX----XXXXXIHFASQKGHLEVVRELLASGA 458 TP+H A G+VD +K L H+ + E + + + Sbjct: 845 TPVHAAVDTGNVDSLKLLMYHRIPAHGNSFNEEESESSVFDLDGGEESPEGISKPVVPAD 904 Query: 459 SVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 + NR+G+TA H AA ++ L R G Sbjct: 905 LINHANREGWTAAHIAASKGFKNCLEILCRHG 936
>NOTC4_HUMAN (Q99466) Neurogenic locus notch homolog protein 4 precursor (Notch 4)| (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain] Length = 2003 Score = 50.4 bits (119), Expect = 3e-06 Identities = 37/123 (30%), Positives = 59/123 (47%), Gaps = 1/123 (0%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AAR A L ++ N DR RTPLH A A +V + L + + Sbjct: 1638 LHLAARFSRPTAARRLLEAGANP-NQPDRAGRTPLHAAVAADAREVCQLLLRSRQTAVDA 1696 Query: 375 XXXXXXX-IHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRR 551 + A++ ++V EL+A+ A V A+++ G TALH+AA ++ + L++ Sbjct: 1697 RTEDGTTPLMLAARLAVEDLVEELIAAQADVGARDKWGKTALHWAAAVNNARAARSLLQA 1756 Query: 552 GVD 560 G D Sbjct: 1757 GAD 1759 Score = 41.6 bits (96), Expect = 0.002 Identities = 31/120 (25%), Positives = 52/120 (43%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH A + + L S A+++R TPL LAA D+V+ L + Sbjct: 1671 LHAAVAADAREVCQLLLRSRQTAVDARTEDGTTPLMLAARLAVEDLVEELIAAQADVGAR 1730 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 +H+A+ + R LL +GA A++ + T L AA+ +E+ + L+ G Sbjct: 1731 DKWGKTALHWAAAVNNARAARSLLQAGADKDAQDNREQTPLFLAAREGAVEVAQLLLGLG 1790
>YR634_MIMIV (Q5UR87) Putative ankyrin repeat protein R634| Length = 486 Score = 50.4 bits (119), Expect = 3e-06 Identities = 32/91 (35%), Positives = 48/91 (52%) Frame = +3 Query: 291 TPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKA 470 TPL A GH+++VK L I AS+ GHL +V+ L++ ++ Sbjct: 177 TPLIWACHNGHLEIVKYLVDQ---GADVNSQSHKSIITASKMGHLGIVKYLVSKTTNIDW 233 Query: 471 KNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 ++ A FAAQN+HLE+VKYLV G ++ Sbjct: 234 RHNY---AAAFAAQNNHLEIVKYLVNEGANL 261 Score = 47.4 bits (111), Expect = 3e-05 Identities = 38/126 (30%), Positives = 61/126 (48%) Frame = +3 Query: 186 DLKLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXX 365 D L A +G V+ L D +NS+ S + A+ GH+ +VK L Sbjct: 176 DTPLIWACHNGHLEIVKYLVDQGA-DVNSQSHKS---IITASKMGHLGIVKYLVSKTTNI 231 Query: 366 XXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLV 545 FA+Q HLE+V+ L+ GA+++ ++ + AA+N HL++VKYLV Sbjct: 232 DWRHNYAAA---FAAQNNHLEIVKYLVNEGANLEIEDG---CIIRVAAKNGHLDIVKYLV 285 Query: 546 RRGVDI 563 G++I Sbjct: 286 SLGMEI 291 Score = 46.2 bits (108), Expect = 6e-05 Identities = 23/55 (41%), Positives = 35/55 (63%) Frame = +3 Query: 405 ASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDITT 569 A++ GHLE+++ L++ G S++ K K AL A HLE+VKYLV G ++ T Sbjct: 345 AAEYGHLEIIKYLVSQGISLEKKINK---ALIVACSKGHLEIVKYLVENGANVKT 396 Score = 45.4 bits (106), Expect = 1e-04 Identities = 28/88 (31%), Positives = 44/88 (50%) Frame = +3 Query: 306 AAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKG 485 AA GH++++K L + A KGHLE+V+ L+ +GA+VK Sbjct: 345 AAEYGHLEIIKYLVSQ---GISLEKKINKALIVACSKGHLEIVKYLVENGANVKTNEG-- 399 Query: 486 FTALHFAAQNSHLELVKYLVRRGVDITT 569 L A ++L++ KYLV G D+T+ Sbjct: 400 -LPLRQACWGNYLDIAKYLVSNGADVTS 426 Score = 42.7 bits (99), Expect = 7e-04 Identities = 28/91 (30%), Positives = 46/91 (50%) Frame = +3 Query: 297 LHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKN 476 L+ A GH+D+ + L + AS G+L++V+ L++ GA+ + Sbjct: 119 LNRAVENGHMDIFEYLISK---GADLYANKNTLVRCASYGGNLDMVKYLISIGANFRENC 175 Query: 477 RKGFTALHFAAQNSHLELVKYLVRRGVDITT 569 T L +A N HLE+VKYLV +G D+ + Sbjct: 176 D---TPLIWACHNGHLEIVKYLVDQGADVNS 203 Score = 37.4 bits (85), Expect = 0.030 Identities = 16/49 (32%), Positives = 32/49 (65%) Frame = +3 Query: 417 GHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 G L+ ++ L++ GA+V+ N AL+ A +N H+++ +YL+ +G D+ Sbjct: 96 GKLDSIKRLVSMGANVREHND---VALNRAVENGHMDIFEYLISKGADL 141 Score = 32.0 bits (71), Expect = 1.3 Identities = 25/97 (25%), Positives = 39/97 (40%), Gaps = 11/97 (11%) Frame = +3 Query: 306 AAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKN--- 476 AA H+++VK L I A++ GHL++V+ L++ G + K Sbjct: 242 AAQNNHLEIVKYLVNE---GANLEIEDGCIIRVAAKNGHLDIVKYLVSLGMEIGFKKILI 298 Query: 477 --------RKGFTALHFAAQNSHLELVKYLVRRGVDI 563 K + A + HL +VKY V G I Sbjct: 299 GTSNFGVVNKITPVIGSAVEGGHLSMVKYFVSIGATI 335
>CTTB2_OTOGA (Q2QLG9) Cortactin-binding protein 2 (CortBP2)| Length = 1655 Score = 50.4 bits (119), Expect = 3e-06 Identities = 30/117 (25%), Positives = 56/117 (47%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 L+ AA++G V L +++ +N+ D+ TPL AA GH + V+ L + Sbjct: 739 LYSAAKNGHTDCVRLLLNAEA-QVNAADKNGFTPLCAAAAQGHFECVELLIAYDAHINHA 797 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLV 545 ++ A + G+ E ++ LL +G + K R G+T +H ++ +K L+ Sbjct: 798 ADEGQTPLYLACKNGNKECIKLLLEAGTNRNVKTRDGWTPVHAVVDTGDVDSLKLLM 854 Score = 50.1 bits (118), Expect = 4e-06 Identities = 32/122 (26%), Positives = 54/122 (44%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 L +AA G+ + L + + L +N + L+ AA GH D V+ L + Sbjct: 705 LQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLNAEAQVNAA 764 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 + A+ +GH E V L+A A + +G T L+ A +N + E +K L+ G Sbjct: 765 DKNGFTPLCAAAAQGHFECVELLIAYDAHINHAADEGQTPLYLACKNGNKECIKLLLEAG 824 Query: 555 VD 560 + Sbjct: 825 TN 826 Score = 30.0 bits (66), Expect = 4.8 Identities = 28/127 (22%), Positives = 51/127 (40%), Gaps = 5/127 (3%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 L+ A ++G+ ++ L ++ N + R TP+H G VD +K L H+ Sbjct: 805 LYLACKNGNKECIKLLLEAGTNR-NVKTRDGWTPVHAVVDTGDVDSLKLLMYHRAPARGN 863 Query: 375 XXXX----XXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYL 542 + E + + + + NR+G+TA H AA ++ L Sbjct: 864 SLNEEEPKSDIFDLDEGEESPEGISKPVIPADLINYANREGWTAAHIAASKGFKNCLEIL 923 Query: 543 VR-RGVD 560 R RG++ Sbjct: 924 CRHRGLE 930
>PME5_CAEEL (Q9TXQ1) Poly(ADP-ribose) polymerase pme-5 (EC 2.4.2.30) (Poly| ADP-ribose metabolism enzyme 5) Length = 2276 Score = 50.4 bits (119), Expect = 3e-06 Identities = 39/144 (27%), Positives = 60/144 (41%), Gaps = 20/144 (13%) Frame = +3 Query: 195 LHKAARSGDAAAV----------------ESLCDSDPLALNSRDRLSRTPLHLAAWAGHV 326 LH AAR+G A ES +D +N+R R + LHLA ++ Sbjct: 416 LHVAARAGRAVNCTFLMKEMLDLEKGDDGESTIRADRSIINARTRSGNSALHLAVLRNNL 475 Query: 327 DVVKCLCKHKXXX----XXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTA 494 DVV L + A KG+LE+ ++L+ GA V+ K++K T Sbjct: 476 DVVDALLAEPTIVVDNPTSTGQNRLTPLMMACGKGYLEMAKKLVEKGALVEGKDKKKRTP 535 Query: 495 LHFAAQNSHLELVKYLVRRGVDIT 566 L A N + +L+ +G +T Sbjct: 536 LIHAMLNGQIHTAAFLLAKGASLT 559 Score = 38.9 bits (89), Expect = 0.010 Identities = 30/108 (27%), Positives = 45/108 (41%) Frame = +3 Query: 219 DAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXI 398 DA E D ++RL TPL +A G++++ K L + + Sbjct: 479 DALLAEPTIVVDNPTSTGQNRL--TPLMMACGKGYLEMAKKLVEKGALVEGKDKKKRTPL 536 Query: 399 HFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYL 542 A G + LLA GAS+ + G TA H+AA L+ +K L Sbjct: 537 IHAMLNGQIHTAAFLLAKGASLTLADSSGNTAAHYAAAYGFLDCLKLL 584 Score = 31.2 bits (69), Expect = 2.2 Identities = 34/141 (24%), Positives = 53/141 (37%), Gaps = 21/141 (14%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKH------- 353 +H AA + A +E L + ++ + + TPLH+AA AG L K Sbjct: 383 MHYAACAPGTAPMEFLLKNGG-SVTMLTKQTETPLHVAARAGRAVNCTFLMKEMLDLEKG 441 Query: 354 ----------KXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASV----KAKNRKGFT 491 + +H A + +L+VV LLA V + + T Sbjct: 442 DDGESTIRADRSIINARTRSGNSALHLAVLRNNLDVVDALLAEPTIVVDNPTSTGQNRLT 501 Query: 492 ALHFAAQNSHLELVKYLVRRG 554 L A +LE+ K LV +G Sbjct: 502 PLMMACGKGYLEMAKKLVEKG 522
>ANKS3_HUMAN (Q6ZW76) Ankyrin repeat and SAM domain-containing protein 3| Length = 656 Score = 50.4 bits (119), Expect = 3e-06 Identities = 34/124 (27%), Positives = 54/124 (43%) Frame = +3 Query: 189 LKLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXX 368 L LH AA G V+ L LN ++ TPL A++ GH +V L + Sbjct: 37 LDLHTAASIGQYEVVKECVQRRELDLNKKNGGGWTPLMYASYIGHDTIVHLLLEAGVSVN 96 Query: 369 XXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVR 548 + AS G+ + LL GA ++ K+ +G+TAL H +V++L+ Sbjct: 97 VPTPEGQTPLMLASSCGNESIAYFLLQQGAELEMKDIQGWTALFHCTSAGHQHMVRFLLD 156 Query: 549 RGVD 560 G + Sbjct: 157 SGAN 160 Score = 39.3 bits (90), Expect = 0.008 Identities = 27/93 (29%), Positives = 41/93 (44%), Gaps = 1/93 (1%) Frame = +3 Query: 288 RTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVK 467 +TPL LA+ G+ + L + + + GH +VR LL SGA+ Sbjct: 103 QTPLMLASSCGNESIAYFLLQQGAELEMKDIQGWTALFHCTSAGHQHMVRFLLDSGANAN 162 Query: 468 AKNR-KGFTALHFAAQNSHLELVKYLVRRGVDI 563 + GFT L AA H +V+Y + GV + Sbjct: 163 VREPICGFTPLMEAAAAGHEIIVQYFLNHGVKV 195
>YL045_MIMIV (Q5UPB6) Putative ankyrin repeat protein L45| Length = 227 Score = 50.1 bits (118), Expect = 4e-06 Identities = 24/53 (45%), Positives = 38/53 (71%) Frame = +3 Query: 405 ASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 AS+ GH+E+V L++ G+ V+A N A+ +A++N HLE+VKYLV +G D+ Sbjct: 116 ASEYGHIEIVEYLVSKGSDVRADNDY---AVIYASKNGHLEIVKYLVSQGCDV 165 Score = 47.4 bits (111), Expect = 3e-05 Identities = 26/86 (30%), Positives = 49/86 (56%) Frame = +3 Query: 303 LAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRK 482 LA+ GH+++V+ L + +AS+ GHLE+V+ L++ G V++ + Sbjct: 115 LASEYGHIEIVEYLVSK---GSDVRADNDYAVIYASKNGHLEIVKYLVSQGCDVRSCDS- 170 Query: 483 GFTALHFAAQNSHLELVKYLVRRGVD 560 A+ A++ HLE+VK+LV++G + Sbjct: 171 --YAVRLASEYGHLEIVKFLVKKGAN 194 Score = 42.7 bits (99), Expect = 7e-04 Identities = 26/83 (31%), Positives = 43/83 (51%) Frame = +3 Query: 318 GHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTAL 497 GH+++VK L + AS+ GHLE+V+ L+ GA+ +A N A+ Sbjct: 150 GHLEIVKYLVSQ---GCDVRSCDSYAVRLASEYGHLEIVKFLVKKGANYRALNHH---AV 203 Query: 498 HFAAQNSHLELVKYLVRRGVDIT 566 A++N H E+V++L+ IT Sbjct: 204 IEASKNKHYEIVEFLMNYSTGIT 226 Score = 34.3 bits (77), Expect = 0.26 Identities = 17/56 (30%), Positives = 34/56 (60%) Frame = +3 Query: 396 IHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 ++ + + G LE+V+ L+ GA++ A+ A++ H+E+V+YLV +G D+ Sbjct: 83 LNASCKNGKLEIVKLLVDLGANIFHNEN---CAMMLASEYGHIEIVEYLVSKGSDV 135
>ANKR7_HUMAN (Q92527) Ankyrin repeat domain-containing protein 7| (Testis-specific protein TSA806) Length = 201 Score = 50.1 bits (118), Expect = 4e-06 Identities = 34/123 (27%), Positives = 57/123 (46%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH A +G V L + +N RD +++PL A + D L Sbjct: 10 LHLACANGHTDVVLFLIEQQ-CKINVRDSENKSPLIKAVQCQNEDCATILLNFGADPDLR 68 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 +H+A L +V +LL A ++AKN+ G+T L A N++ ++VK+L+ +G Sbjct: 69 DIRYNTVLHYAVCGQSLSLVEKLLEYEADLEAKNKDGYTPLLVAVINNNPKMVKFLLEKG 128 Query: 555 VDI 563 D+ Sbjct: 129 ADV 131 Score = 33.5 bits (75), Expect = 0.44 Identities = 30/115 (26%), Positives = 50/115 (43%) Frame = +3 Query: 219 DAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXI 398 D A + +DP + RD T LH A + +V+ L +++ + Sbjct: 53 DCATILLNFGADP---DLRDIRYNTVLHYAVCGQSLSLVEKLLEYEADLEAKNKDGYTPL 109 Query: 399 HFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 A + ++V+ LL GA V A + TAL A LVK L+++GV++ Sbjct: 110 LVAVINNNPKMVKFLLEKGADVNASDNYQRTALILAVSGEPPCLVKLLLQQGVEL 164
>YR847_MIMIV (Q5UP12) Putative ankyrin repeat protein R847 (Fragment)| Length = 147 Score = 50.1 bits (118), Expect = 4e-06 Identities = 31/81 (38%), Positives = 47/81 (58%) Frame = +3 Query: 303 LAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRK 482 LA+ GH+DVVK L I +AS GHLEVV+ L++ GA+++A+N Sbjct: 39 LASENGHLDVVKYLV---VLGVNIRVDNDCAIRWASLHGHLEVVKYLVSQGANIRAENN- 94 Query: 483 GFTALHFAAQNSHLELVKYLV 545 A+ +A++N H E+V YL+ Sbjct: 95 --FAVEWASRNGHREIVDYLI 113 Score = 47.4 bits (111), Expect = 3e-05 Identities = 24/53 (45%), Positives = 39/53 (73%) Frame = +3 Query: 405 ASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 AS G+L +V+ L++ GA+++AKN + A+ A++N HL++VKYLV GV+I Sbjct: 10 ASCNGYLSIVKYLVSQGANIRAKNDR---AVILASENGHLDVVKYLVVLGVNI 59 Score = 45.4 bits (106), Expect = 1e-04 Identities = 27/86 (31%), Positives = 46/86 (53%) Frame = +3 Query: 306 AAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKG 485 A+ G++ +VK L + AS+ GHL+VV+ L+ G +++ N Sbjct: 10 ASCNGYLSIVKYLVSQ---GANIRAKNDRAVILASENGHLDVVKYLVVLGVNIRVDND-- 64 Query: 486 FTALHFAAQNSHLELVKYLVRRGVDI 563 A+ +A+ + HLE+VKYLV +G +I Sbjct: 65 -CAIRWASLHGHLEVVKYLVSQGANI 89
>POT14_HUMAN (Q6S5H5) Prostate, ovary, testis expressed protein on chromosome 14| Length = 594 Score = 50.1 bits (118), Expect = 4e-06 Identities = 37/124 (29%), Positives = 52/124 (41%) Frame = +3 Query: 192 KLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXX 371 KLH+AA G + + +N +D+ RT LHLA+ G+ +VVK L + Sbjct: 142 KLHRAAWWGKVPRKDLIVMLKDTDMNKKDKQKRTALHLASANGNSEVVKLLLDRRCQLNI 201 Query: 372 XXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRR 551 + A Q E LL G + G TALH+A N + K L+ Sbjct: 202 LDNKKRTALTKAVQCQEDECALMLLEHGTDPNIPDEYGNTALHYAIYNEDKLMAKALLLY 261 Query: 552 GVDI 563 G DI Sbjct: 262 GADI 265 Score = 31.6 bits (70), Expect = 1.7 Identities = 24/95 (25%), Positives = 39/95 (41%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH A+ +G++ V+ L D LN D RT L A + L +H Sbjct: 177 LHLASANGNSEVVKLLLDRR-CQLNILDNKKRTALTKAVQCQEDECALMLLEHGTDPNIP 235 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNR 479 +H+A + + LL GA +++KN+ Sbjct: 236 DEYGNTALHYAIYNEDKLMAKALLLYGADIESKNK 270
>YR864_MIMIV (Q5UP19) Putative ankyrin repeat protein R864| Length = 299 Score = 50.1 bits (118), Expect = 4e-06 Identities = 26/53 (49%), Positives = 38/53 (71%) Frame = +3 Query: 405 ASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 AS GHLEVV+ L++ GA++K+KN + + +A+Q+ LE+VKYLV G DI Sbjct: 116 ASGGGHLEVVKYLVSQGANIKSKNNR---VVGWASQHGRLEVVKYLVSLGADI 165 Score = 48.1 bits (113), Expect = 2e-05 Identities = 23/58 (39%), Positives = 38/58 (65%) Frame = +3 Query: 396 IHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDITT 569 + +ASQ GH+++V+ L + GA ++ N + A++N H+E+VKYLV +G DI T Sbjct: 233 VKWASQCGHIDIVKYLASQGADIRNDNDY---CVGLASKNGHIEVVKYLVSQGADIKT 287 Score = 47.8 bits (112), Expect = 2e-05 Identities = 30/90 (33%), Positives = 48/90 (53%), Gaps = 3/90 (3%) Frame = +3 Query: 303 LAAWA---GHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAK 473 + WA G ++VVK L + +AS+ GHLEV + L++ GA +++K Sbjct: 142 VVGWASQHGRLEVVKYLVS---LGADIRSNDDYAVRWASEHGHLEVAKYLVSLGADIRSK 198 Query: 474 NRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 + L A+QN +LE++KY+V G DI Sbjct: 199 Y---YYILCGASQNGYLEIIKYIVSLGADI 225 Score = 46.2 bits (108), Expect = 6e-05 Identities = 21/53 (39%), Positives = 37/53 (69%) Frame = +3 Query: 405 ASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 ASQ G+LE+++ +++ GA ++A N A+ +A+Q H+++VKYL +G DI Sbjct: 206 ASQNGYLEIIKYIVSLGADIRAYNN---CAVKWASQCGHIDIVKYLASQGADI 255 Score = 39.3 bits (90), Expect = 0.008 Identities = 20/50 (40%), Positives = 33/50 (66%) Frame = +3 Query: 414 KGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 KG L++V+ L+ GA++++ N A+ A+ HLE+VKYLV +G +I Sbjct: 89 KGQLKIVQHLINIGANIESNNNY---AVLLASGGGHLEVVKYLVSQGANI 135 Score = 36.2 bits (82), Expect = 0.067 Identities = 19/57 (33%), Positives = 29/57 (50%) Frame = +3 Query: 306 AAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKN 476 A+ GH+D+VK L + AS+ GH+EVV+ L++ GA +K N Sbjct: 236 ASQCGHIDIVKYLASQ---GADIRNDNDYCVGLASKNGHIEVVKYLVSQGADIKTYN 289
>V240_FOWPV (P14360) Putative ankyrin repeat protein FPV240 (BamHI-ORF7)| Length = 410 Score = 50.1 bits (118), Expect = 4e-06 Identities = 40/157 (25%), Positives = 61/157 (38%), Gaps = 34/157 (21%) Frame = +3 Query: 192 KLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXX 371 +LH+A GD VE L DS + + TPLHLA + ++D+++ L Sbjct: 70 ELHEAVEEGDVVKVEELLDSGKFINDVIYKKGNTPLHLATISKNLDMMRLLIARGADTDV 129 Query: 372 XXXXXXXXIH---------------------------------FASQKGHLEVVRELLAS 452 +H A KG EV R LL S Sbjct: 130 PNTDRFTPLHLAVMSKDIKGIELLLDHRACTNIEDCYGCTPLIIAMSKGDTEVCRMLLDS 189 Query: 453 GASVK-AKNRKGFTALHFAAQNSHLELVKYLVRRGVD 560 GA++ R TA+ +A QN+ +++V ++RG D Sbjct: 190 GANIDYFSKRPCVTAMCYAIQNNKIDMVSMFLKRGAD 226
>YR787_MIMIV (Q5UQ08) Putative ankyrin repeat protein R787| Length = 437 Score = 50.1 bits (118), Expect = 4e-06 Identities = 39/129 (30%), Positives = 63/129 (48%), Gaps = 2/129 (1%) Frame = +3 Query: 186 DLKLHKAARSGDAAAVESLCD--SDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKX 359 +L L +AA +G + V+ L D +D A NS + ++ GH++VV+ L K Sbjct: 246 NLALRQAAENGHLSIVKYLVDLGADINAKNS------CAIRWSSRQGHLNVVQFLINQKA 299 Query: 360 XXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKY 539 I+ A +KG+ ++++ L+ SGA K N L AA H+ +V+Y Sbjct: 300 DVNAKDNYA---INHACKKGYTDIIKCLVESGAEFKHNNN---YCLRIAAGKGHMSIVRY 353 Query: 540 LVRRGVDIT 566 LV +G D T Sbjct: 354 LVEKGSDYT 362 Score = 47.0 bits (110), Expect = 4e-05 Identities = 40/128 (31%), Positives = 58/128 (45%), Gaps = 2/128 (1%) Frame = +3 Query: 186 DLKLHKAARSGDAAAVESLCD--SDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKX 359 D L +AA G V+ LC+ SD ++S++ L+ L A GH+D+V L Sbjct: 157 DAMLREAALKGQFEMVKYLCEIGSD---VSSKNNLT---LVWAIIGGHIDIVDYLISK-- 208 Query: 360 XXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKY 539 + +A GH +V + +KA + AL AA+N HL +VKY Sbjct: 209 --GADYRQINNPLAWACHHGHFNIVEYFVDKNVDIKADDN---LALRQAAENGHLSIVKY 263 Query: 540 LVRRGVDI 563 LV G DI Sbjct: 264 LVDLGADI 271 Score = 41.6 bits (96), Expect = 0.002 Identities = 26/81 (32%), Positives = 39/81 (48%), Gaps = 1/81 (1%) Frame = +3 Query: 321 HVDVVKCL-CKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTAL 497 ++D +K + H + A + GHL VV+ L+ GA +KA+ + L Sbjct: 75 YIDKIKLIDTSHSKNTRFELSDIQNYLRKACKYGHLSVVKYLVGRGADIKAEK----SYL 130 Query: 498 HFAAQNSHLELVKYLVRRGVD 560 N HLE+VKY+V GVD Sbjct: 131 TGPITNGHLEVVKYMVSMGVD 151 Score = 40.4 bits (93), Expect = 0.004 Identities = 24/95 (25%), Positives = 45/95 (47%) Frame = +3 Query: 279 RLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGA 458 R PL A GH ++V+ + A++ GHL +V+ L+ GA Sbjct: 213 RQINNPLAWACHHGHFNIVEYFVDKNVDIKADDNLA---LRQAAENGHLSIVKYLVDLGA 269 Query: 459 SVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 + AKN A+ ++++ HL +V++L+ + D+ Sbjct: 270 DINAKNS---CAIRWSSRQGHLNVVQFLINQKADV 301 Score = 32.7 bits (73), Expect = 0.74 Identities = 30/103 (29%), Positives = 43/103 (41%), Gaps = 2/103 (1%) Frame = +3 Query: 267 NSRDRLS--RTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRE 440 N+R LS + L A GH+ VVK L I GHLEVV+ Sbjct: 89 NTRFELSDIQNYLRKACKYGHLSVVKYLVGRGADIKAEKSYLTGPI----TNGHLEVVKY 144 Query: 441 LLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDITT 569 +++ G + + L AA E+VKYL G D+++ Sbjct: 145 MVSMGVDFRYDDD---AMLREAALKGQFEMVKYLCEIGSDVSS 184
>SHARK_DROME (Q24145) Tyrosine-protein kinase shark (EC 2.7.10.2)| Length = 939 Score = 49.7 bits (117), Expect = 6e-06 Identities = 31/118 (26%), Positives = 59/118 (50%), Gaps = 1/118 (0%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH+A ++ V L +++++ +T LHLAA D++K L K Sbjct: 124 LHRATSKNESKVVFELLKCGYRNFDAKNQDGQTALHLAALHSDEDILKHLLNAKVQVNSS 183 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKN-RKGFTALHFAAQNSHLELVKYLV 545 +H+A++ +R L+++ A+V+ +N G+ LH AA++ +LE V+ L+ Sbjct: 184 DSFGCQPLHYAARSKPASFIRTLISAQANVQGRNIDNGYVPLHEAAKHGNLEAVQELL 241 Score = 40.0 bits (92), Expect = 0.005 Identities = 23/59 (38%), Positives = 36/59 (61%), Gaps = 1/59 (1%) Frame = +3 Query: 396 IHFASQKGHLEVVRELLASG-ASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDITT 569 +H A+ K +VV ELL G + AKN+ G TALH AA +S +++K+L+ V + + Sbjct: 124 LHRATSKNESKVVFELLKCGYRNFDAKNQDGQTALHLAALHSDEDILKHLLNAKVQVNS 182
>YL014_MIMIV (Q5UP96) Putative ankyrin repeat protein L14 (Fragment)| Length = 107 Score = 49.7 bits (117), Expect = 6e-06 Identities = 24/53 (45%), Positives = 39/53 (73%) Frame = +3 Query: 396 IHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 + FAS+ GHLEVV+ L++ GA+++A N A+ +A++N HL++V+YLV G Sbjct: 54 VRFASRNGHLEVVKYLVSLGANIRADND---CAVRWASRNGHLDVVEYLVSLG 103 Score = 45.8 bits (107), Expect = 8e-05 Identities = 24/52 (46%), Positives = 37/52 (71%) Frame = +3 Query: 408 SQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 S K ++EVV+ L++ GA+++A N A+ FA++N HLE+VKYLV G +I Sbjct: 28 SIKVYIEVVKYLVSQGANIRADND---CAVRFASRNGHLEVVKYLVSLGANI 76
>YR837_MIMIV (Q5UQI8) Putative ankyrin repeat protein R837| Length = 626 Score = 49.7 bits (117), Expect = 6e-06 Identities = 23/54 (42%), Positives = 36/54 (66%) Frame = +3 Query: 405 ASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDIT 566 A+ GH ++V L+ GA++K++N AL FA +N H +VK+L+ +GVDIT Sbjct: 118 AAANGHSDIVEYLVNGGANIKSRNNY---ALRFAVKNGHYNMVKFLIEQGVDIT 168 Score = 30.0 bits (66), Expect = 4.8 Identities = 17/51 (33%), Positives = 28/51 (54%) Frame = +3 Query: 411 QKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 Q G++ +V+ + GA+ + K L AA N H ++V+YLV G +I Sbjct: 90 QNGNILLVKFFIEKGANHRYSEDK---PLGIAAANGHSDIVEYLVNGGANI 137
>ANR10_MOUSE (Q99LW0) Ankyrin repeat domain-containing protein 10| Length = 415 Score = 49.7 bits (117), Expect = 6e-06 Identities = 38/126 (30%), Positives = 58/126 (46%), Gaps = 6/126 (4%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLA-LNSRDRL-SRTPLHLAAWAGHVDVVKCLCK----HK 356 LH+A R GD A+ SL P A L + D TP+H WA H ++CL + Sbjct: 25 LHRACRDGDLVALCSLLPHTPRAHLAAEDSFYGWTPVH---WAAHFGKLECLMQLVRAGA 81 Query: 357 XXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVK 536 H A+ GH + + L+ +GA++ + +G T +H AA++ LE + Sbjct: 82 SLNVSTTRYAQTPAHIAAFGGHPQCLVWLIQAGANINKPDCEGETPIHKAARSGSLECIT 141 Query: 537 YLVRRG 554 LV G Sbjct: 142 ALVGSG 147
>ANKS3_MOUSE (Q9CZK6) Ankyrin repeat and SAM domain-containing protein 3| Length = 655 Score = 49.7 bits (117), Expect = 6e-06 Identities = 34/124 (27%), Positives = 53/124 (42%) Frame = +3 Query: 189 LKLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXX 368 L LH AA G V+ L LN ++ T L A++ GH +V L + Sbjct: 37 LDLHTAASIGQHEVVKECVQRGELDLNKKNGGGWTALMYASYIGHDTIVHLLLEAGVSVN 96 Query: 369 XXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVR 548 + AS G+ + LL GA ++ K+ G+TAL H ++VK+L+ Sbjct: 97 VPTPEGQTPLMLASSCGNESIAYFLLQQGAELEMKDIHGWTALFHCTSAGHQQMVKFLLE 156 Query: 549 RGVD 560 G + Sbjct: 157 SGAN 160 Score = 41.2 bits (95), Expect = 0.002 Identities = 26/95 (27%), Positives = 44/95 (46%), Gaps = 1/95 (1%) Frame = +3 Query: 288 RTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVK 467 +TPL LA+ G+ + L + + + GH ++V+ LL SGA+ Sbjct: 103 QTPLMLASSCGNESIAYFLLQQGAELEMKDIHGWTALFHCTSAGHQQMVKFLLESGANAN 162 Query: 468 AKNR-KGFTALHFAAQNSHLELVKYLVRRGVDITT 569 + G+T L AA + H +V+Y + GV + T Sbjct: 163 VREPVYGYTPLMEAAASGHEIIVQYFLNHGVKVDT 197
>CTTB2_HORSE (Q2QLA2) Cortactin-binding protein 2 (CortBP2)| Length = 1665 Score = 49.7 bits (117), Expect = 6e-06 Identities = 32/122 (26%), Positives = 55/122 (45%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 L +AA G+ + L + + L +N + L+ AA GH D V+ L + Sbjct: 715 LQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLNAEAQVDAA 774 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 + A+ +GH + V+ L+A A++ G T L+ A +N + E +K L+ G Sbjct: 775 DKNGFTPLCAAAAQGHFKCVQLLIAYDANINHAADGGQTPLYLACKNGNKECIKLLLEAG 834 Query: 555 VD 560 D Sbjct: 835 SD 836 Score = 49.3 bits (116), Expect = 8e-06 Identities = 30/117 (25%), Positives = 57/117 (48%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 L+ AA++G V L +++ +++ D+ TPL AA GH V+ L + Sbjct: 749 LYSAAKNGHTDCVRLLLNAEA-QVDAADKNGFTPLCAAAAQGHFKCVQLLIAYDANINHA 807 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLV 545 ++ A + G+ E ++ LL +G+ K R G+T +H A +++ +K L+ Sbjct: 808 ADGGQTPLYLACKNGNKECIKLLLEAGSDRSIKTRDGWTPVHAAVDTGNVDSLKLLM 864 Score = 38.9 bits (89), Expect = 0.010 Identities = 27/92 (29%), Positives = 43/92 (46%), Gaps = 1/92 (1%) Frame = +3 Query: 291 TPLHLAAWAGHVDVVKCLCKHKXXXXXXX-XXXXXXIHFASQKGHLEVVRELLASGASVK 467 T L AA G+V ++ L + ++ A++ GH + VR LL + A V Sbjct: 713 TLLQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLNAEAQVD 772 Query: 468 AKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 A ++ GFT L AA H + V+ L+ +I Sbjct: 773 AADKNGFTPLCAAAAQGHFKCVQLLIAYDANI 804 Score = 32.0 bits (71), Expect = 1.3 Identities = 29/126 (23%), Positives = 54/126 (42%), Gaps = 6/126 (4%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDS-DPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXX 371 L+ A ++G+ ++ L ++ ++ +RD TP+H A G+VD +K L H+ Sbjct: 815 LYLACKNGNKECIKLLLEAGSDRSIKTRD--GWTPVHAAVDTGNVDSLKLLMYHRAPAHG 872 Query: 372 XXXXXX---XXIHFASQKGHL--EVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVK 536 I ++G E + + + +R+G+TA H AA ++ Sbjct: 873 SSLHKEEPESSIFDLDRQGEESPEGTFKPVVPADLINQADREGWTAAHIAASKGFKNCLE 932 Query: 537 YLVRRG 554 L R G Sbjct: 933 ILCRHG 938
>POTE8_HUMAN (Q6S8J7) Prostate, ovary, testis expressed protein on chromosome 8| Length = 498 Score = 49.7 bits (117), Expect = 6e-06 Identities = 37/124 (29%), Positives = 51/124 (41%) Frame = +3 Query: 192 KLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXX 371 KLH+AA G+ + + +N RD+ RT LHLA G+ +VV L + Sbjct: 68 KLHRAAWWGEVPRADLIVMLRGPGINKRDKKKRTALHLACANGNSEVVSLLLDRQCQLHV 127 Query: 372 XXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRR 551 + A Q E LL G + G TALH+A N + K L+ Sbjct: 128 FDSKKRTALIKAVQCQEDECALMLLQHGTDPNLPDMYGNTALHYAVYNEDKLMAKTLLLY 187 Query: 552 GVDI 563 G DI Sbjct: 188 GADI 191
>V222_FOWPV (Q9J513) Putative ankyrin repeat protein FPV222| Length = 747 Score = 49.7 bits (117), Expect = 6e-06 Identities = 25/99 (25%), Positives = 47/99 (47%) Frame = +3 Query: 264 LNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVREL 443 +N + + TPLH+A+ +G +V+ L H +H++ L + L Sbjct: 130 VNMNNMKNITPLHIASSSGSYKMVELLLLHGANTNALTSYGETSLHYSVSSNDLNISELL 189 Query: 444 LASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVD 560 + +G +V N+ TAL A + ++LV+ L+ +G D Sbjct: 190 IENGTNVNVANKDSITALIIAVEIMSIDLVRLLLDKGAD 228 Score = 40.8 bits (94), Expect = 0.003 Identities = 25/91 (27%), Positives = 41/91 (45%), Gaps = 3/91 (3%) Frame = +3 Query: 297 LHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQ---KGHLEVVRELLASGASVK 467 +H A H +++ L ++ H+A + + ++ L +GAS Sbjct: 333 MHYAVIRKHYEMLNILIRYDAYTDVKDRQQNTPAHYAVKLPISESCKYLKLLKLAGASFN 392 Query: 468 AKNRKGFTALHFAAQNSHLELVKYLVRRGVD 560 NRKG T LH A + ++ E VKYL+ G D Sbjct: 393 LTNRKGRTPLHTACKYNNTEAVKYLIESGCD 423 Score = 39.3 bits (90), Expect = 0.008 Identities = 19/81 (23%), Positives = 39/81 (48%) Frame = +3 Query: 321 HVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALH 500 ++++ K L ++ +H AS G ++V LL GA+ A G T+LH Sbjct: 116 NLEIAKMLIQNGALVNMNNMKNITPLHIASSSGSYKMVELLLLHGANTNALTSYGETSLH 175 Query: 501 FAAQNSHLELVKYLVRRGVDI 563 ++ ++ L + + L+ G ++ Sbjct: 176 YSVSSNDLNISELLIENGTNV 196 Score = 34.7 bits (78), Expect = 0.20 Identities = 15/51 (29%), Positives = 29/51 (56%) Frame = +3 Query: 408 SQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVD 560 ++ +LE+ + L+ +GA V N K T LH A+ + ++V+ L+ G + Sbjct: 112 NENRNLEIAKMLIQNGALVNMNNMKNITPLHIASSSGSYKMVELLLLHGAN 162 Score = 31.6 bits (70), Expect = 1.7 Identities = 14/49 (28%), Positives = 27/49 (55%) Frame = +3 Query: 414 KGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVD 560 K + VR+ L G + KN+ T L+ A ++ +++++K L+ G D Sbjct: 16 KNDVVSVRKYLEKGINPNEKNKDNCTMLYTAVEHRYIDIIKLLLDHGAD 64
>AKR1_ASHGO (Q755Y0) Palmitoyltransferase AKR1 (EC 2.3.1.-) (Ankyrin| repeat-containing protein AKR1) Length = 724 Score = 49.7 bits (117), Expect = 6e-06 Identities = 29/106 (27%), Positives = 49/106 (46%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH + S + + + + + ++S D +T LH AA+ G + V+ L K Sbjct: 162 LHTSTFSSEVMLITYVLFTGQIPVDSPDPTGKTALHWAAYQGDPNTVEALLKFDADVRVV 221 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQ 512 +H+A+ KGH V++ L+ G+ V KN G AL A + Sbjct: 222 DTGGFTPLHWATVKGHPHVLKALIEHGSDVFLKNNDGKNALMIAQE 267 Score = 45.4 bits (106), Expect = 1e-04 Identities = 35/126 (27%), Positives = 56/126 (44%), Gaps = 3/126 (2%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCD--SDPLALNSRDRLSRTPLHLAAWAGHVDVVK-CLCKHKXXX 365 LH A++SG V L + +DPL DR LH + ++ V ++ L + Sbjct: 129 LHWASKSGYVYIVHCLLEHGADPLIT---DRQGYNLLHTSTFSSEVMLITYVLFTGQIPV 185 Query: 366 XXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLV 545 +H+A+ +G V LL A V+ + GFT LH+A H ++K L+ Sbjct: 186 DSPDPTGKTALHWAAYQGDPNTVEALLKFDADVRVVDTGGFTPLHWATVKGHPHVLKALI 245 Query: 546 RRGVDI 563 G D+ Sbjct: 246 EHGSDV 251 Score = 42.0 bits (97), Expect = 0.001 Identities = 21/58 (36%), Positives = 37/58 (63%), Gaps = 3/58 (5%) Frame = +3 Query: 399 HFASQKGHLEVVRELLASGA-SVKAK--NRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 H A Q+G L+ V++++ +G VKA + + LH+A+ N+ L LV+YL+ +G D+ Sbjct: 60 HAACQRGDLKTVKDMIEAGVIDVKADWDEEEQVSGLHWASANNRLNLVRYLIAQGADV 117
>ASZ1_MOUSE (Q8VD46) Ankyrin repeat, SAM and basic leucine zipper| domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein) Length = 475 Score = 49.7 bits (117), Expect = 6e-06 Identities = 30/99 (30%), Positives = 47/99 (47%) Frame = +3 Query: 246 DSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHL 425 ++DP N+ R TP+ AA GH VV L H + +A+++GH Sbjct: 139 NADP---NTACRRLMTPIMYAARDGHTQVVALLVAHGAEVNAQDENGYTALTWAARQGHK 195 Query: 426 EVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYL 542 V+ +LL GA+ + + G T A +N HLE+ +L Sbjct: 196 NVILKLLELGANKMLQTKDGRTPSEIAKRNKHLEIFNFL 234 Score = 48.5 bits (114), Expect = 1e-05 Identities = 35/122 (28%), Positives = 55/122 (45%), Gaps = 3/122 (2%) Frame = +3 Query: 204 AARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKC---LCKHKXXXXXX 374 AA +A V L D A +D+L+ +A V+KC L Sbjct: 86 AASVANAELVRFLLDRGANASFDKDKLTILISACSARGSEEQVLKCVELLLSRNADPNTA 145 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 I +A++ GH +VV L+A GA V A++ G+TAL +AA+ H ++ L+ G Sbjct: 146 CRRLMTPIMYAARDGHTQVVALLVAHGAEVNAQDENGYTALTWAARQGHKNVILKLLELG 205 Query: 555 VD 560 + Sbjct: 206 AN 207 Score = 40.8 bits (94), Expect = 0.003 Identities = 20/48 (41%), Positives = 33/48 (68%) Frame = +3 Query: 417 GHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVD 560 G + +V+ELL SG +V + R G+T L +AA ++ ELV++L+ RG + Sbjct: 57 GDISLVKELLDSGINVDSSFRYGWTPLMYAASVANAELVRFLLDRGAN 104
>RFXK_MOUSE (Q9Z205) DNA-binding protein RFXANK (Regulatory factor X subunit B)| (RFX-B) (Regulatory factor X-associated ankyrin-containing protein) (Ankyrin repeat-containing adapter protein Tvl-1) Length = 269 Score = 49.3 bits (116), Expect = 8e-06 Identities = 34/137 (24%), Positives = 59/137 (43%), Gaps = 10/137 (7%) Frame = +3 Query: 189 LKLHKAARSGDAAAVES----------LCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVK 338 L +H+ A G+ + ++ C S +N D TPL A+ G ++ V+ Sbjct: 91 LSIHQLAAQGELSQLKDHLRKGACPACTCLSGNNLINKPDERGFTPLIWASAFGEIETVR 150 Query: 339 CLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNS 518 L + AS G+ ++VR LL + + G T L +A + + Sbjct: 151 FLLDWGADPHILAKERESALSLASMGGYTDIVRLLLDRDVDINIYDWNGGTPLLYAVRGN 210 Query: 519 HLELVKYLVRRGVDITT 569 H++ V+ L+ RG D+TT Sbjct: 211 HVKCVEALLARGADLTT 227 Score = 33.9 bits (76), Expect = 0.33 Identities = 28/103 (27%), Positives = 47/103 (45%), Gaps = 2/103 (1%) Frame = +3 Query: 204 AARSGDAAAVESLCD--SDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXX 377 A+ G+ V L D +DP L +++R S L LA+ G+ D+V+ L Sbjct: 140 ASAFGEIETVRFLLDWGADPHIL-AKERESA--LSLASMGGYTDIVRLLLDRDVDINIYD 196 Query: 378 XXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFA 506 + +A + H++ V LLA GA + + G+T + A Sbjct: 197 WNGGTPLLYAVRGNHVKCVEALLARGADLTTEADSGYTPMDLA 239
>USH1G_MOUSE (Q80T11) Usher syndrome type-1G protein homolog (Scaffold protein| containing ankyrin repeats and SAM domain) (Jackson shaker protein) Length = 461 Score = 49.3 bits (116), Expect = 8e-06 Identities = 32/115 (27%), Positives = 54/115 (46%) Frame = +3 Query: 198 HKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXX 377 H+AAR G +E L ++ LN+ D TP AA+ G+++ ++ + Sbjct: 6 HRAARDG---YLELLKEATRKELNAPDEDGMTPTLWAAYHGNLESLRLIVSRGGDPDKCD 62 Query: 378 XXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYL 542 +H A+ GHL + L++ GA++ + T L AA H+E V+YL Sbjct: 63 IWGNTPLHLAASNGHLHCLSFLVSFGANIWCLDNDYHTPLDMAAMKGHMECVRYL 117 Score = 35.8 bits (81), Expect = 0.088 Identities = 19/54 (35%), Positives = 30/54 (55%) Frame = +3 Query: 402 FASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 +A+ G+LE +R +++ G + G T LH AA N HL + +LV G +I Sbjct: 38 WAAYHGNLESLRLIVSRGGDPDKCDIWGNTPLHLAASNGHLHCLSFLVSFGANI 91
>USH1G_HUMAN (Q495M9) Usher syndrome type-1G protein (Scaffold protein| containing ankyrin repeats and SAM domain) Length = 461 Score = 49.3 bits (116), Expect = 8e-06 Identities = 32/115 (27%), Positives = 54/115 (46%) Frame = +3 Query: 198 HKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXX 377 H+AAR G +E L ++ LN+ D TP AA+ G+++ ++ + Sbjct: 6 HRAARDG---YLELLKEATRKELNAPDEDGMTPTLWAAYHGNLESLRLIVSRGGDPDKCD 62 Query: 378 XXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYL 542 +H A+ GHL + L++ GA++ + T L AA H+E V+YL Sbjct: 63 IWGNTPLHLAASNGHLHCLSFLVSFGANIWCLDNDYHTPLDMAAMKGHMECVRYL 117 Score = 35.8 bits (81), Expect = 0.088 Identities = 19/54 (35%), Positives = 30/54 (55%) Frame = +3 Query: 402 FASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 +A+ G+LE +R +++ G + G T LH AA N HL + +LV G +I Sbjct: 38 WAAYHGNLESLRLIVSRGGDPDKCDIWGNTPLHLAASNGHLHCLSFLVSFGANI 91
>SHAN1_RAT (Q9WV48) SH3 and multiple ankyrin repeat domains protein 1 (Shank1)| (GKAP/SAPAP-interacting protein) (SPANK-1) (Synamon) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP) Length = 2167 Score = 48.9 bits (115), Expect = 1e-05 Identities = 39/123 (31%), Positives = 55/123 (44%), Gaps = 1/123 (0%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPL-HLAAWAGHVDVVKCLCKHKXXXXX 371 LHKAA + A+ +L D + N +DR TPL H A G + L ++ Sbjct: 251 LHKAACARHCLALTALLDLGG-SPNYKDRRGLTPLFHTAMVGGDPRCCELLLYNRAQLGI 309 Query: 372 XXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRR 551 IH A Q+GH + + LL GA A+N G TALH A + + L+ R Sbjct: 310 ADENGWQEIHQACQRGHSQHLEHLLFYGAEPGAQNASGNTALHICALYNKETCARILLYR 369 Query: 552 GVD 560 G + Sbjct: 370 GAN 372 Score = 33.5 bits (75), Expect = 0.44 Identities = 17/39 (43%), Positives = 22/39 (56%) Frame = +3 Query: 405 ASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSH 521 A +G +EV+R L GA + + R G TALH AA H Sbjct: 221 AQTEGSVEVIRTLCLGGAHIDFRARDGMTALHKAACARH 259
>ASZ1_CALJA (Q2QLG0) Ankyrin repeat, SAM and basic leucine zipper| domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein) Length = 477 Score = 48.9 bits (115), Expect = 1e-05 Identities = 41/160 (25%), Positives = 65/160 (40%), Gaps = 37/160 (23%) Frame = +3 Query: 192 KLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLC-------- 347 K KA +GD + V L DS +++++ R TPL AA + ++V+ L Sbjct: 50 KFKKALTTGDVSLVLELLDSGIISVDATFRYGWTPLMYAASVANAELVRVLLDRGANASF 109 Query: 348 -KHKXXXXXXXXXXXXX----------------------------IHFASQKGHLEVVRE 440 K K I +A++ GH +VV Sbjct: 110 EKDKQTILITACSAHGSEEQILKCVELLLSRNADPNVACRRLMTPIMYAARDGHTQVVAL 169 Query: 441 LLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVD 560 L+ASGA V ++ G+TAL +AA+ H +V L+ G + Sbjct: 170 LVASGAEVNTQDENGYTALTWAARQGHKSIVLKLLELGAN 209 Score = 38.5 bits (88), Expect = 0.014 Identities = 27/99 (27%), Positives = 42/99 (42%) Frame = +3 Query: 246 DSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHL 425 ++DP N R TP+ AA GH VV L + +A+++GH Sbjct: 141 NADP---NVACRRLMTPIMYAARDGHTQVVALLVASGAEVNTQDENGYTALTWAARQGHK 197 Query: 426 EVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYL 542 +V +LL GA+ + + G A +N H E+ L Sbjct: 198 SIVLKLLELGANKMLQTKDGKLPSEIAKRNKHHEIFNLL 236
>OSTF1_MOUSE (Q62422) Osteoclast-stimulating factor 1 (SH3 domain protein 3)| Length = 215 Score = 48.9 bits (115), Expect = 1e-05 Identities = 33/118 (27%), Positives = 56/118 (47%), Gaps = 1/118 (0%) Frame = +3 Query: 186 DLKLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCL-CKHKXX 362 D LH+AA+ G+ + + C + + +N D+ T L+ A GH D+V+ L + Sbjct: 74 DNPLHEAAKRGNLSWLRE-CLDNRVGVNGLDKAGSTALYWACHGGHKDIVEVLFTQPNVE 132 Query: 363 XXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVK 536 +H A+ KG+ ++V+ LLA GA +N + AL A + L+K Sbjct: 133 LNQQNKLGDTALHAAAWKGYADIVQLLLAKGARTDLRNNEKKLALDMATNAACASLLK 190
>RFXK_HUMAN (O14593) DNA-binding protein RFXANK (Regulatory factor X subunit B)| (RFX-B) (Ankyrin repeat family A protein 1) Length = 260 Score = 48.9 bits (115), Expect = 1e-05 Identities = 31/127 (24%), Positives = 56/127 (44%) Frame = +3 Query: 189 LKLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXX 368 L +H+ A G+ ++ +N D TPL A+ G ++ V+ L + Sbjct: 92 LSIHQLAAQGELDQLKEHLRKGDNLVNKPDERGFTPLIWASAFGEIETVRFLLEWGADPH 151 Query: 369 XXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVR 548 + AS G+ ++V LL + + G T L +A + +H++ V+ L+ Sbjct: 152 ILAKERESALSLASTGGYTDIVGLLLERDVDINIYDWNGGTPLLYAVRGNHVKCVEALLA 211 Query: 549 RGVDITT 569 RG D+TT Sbjct: 212 RGADLTT 218 Score = 31.2 bits (69), Expect = 2.2 Identities = 27/103 (26%), Positives = 47/103 (45%), Gaps = 2/103 (1%) Frame = +3 Query: 204 AARSGDAAAVESLCD--SDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXX 377 A+ G+ V L + +DP L +++R S L LA+ G+ D+V L + Sbjct: 131 ASAFGEIETVRFLLEWGADPHIL-AKERESA--LSLASTGGYTDIVGLLLERDVDINIYD 187 Query: 378 XXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFA 506 + +A + H++ V LLA GA + + G+T + A Sbjct: 188 WNGGTPLLYAVRGNHVKCVEALLARGADLTTEADSGYTPMDLA 230
>PYX_DROME (Q9W0T5) Transient receptor potential channel pyrexia| Length = 956 Score = 48.9 bits (115), Expect = 1e-05 Identities = 36/125 (28%), Positives = 56/125 (44%), Gaps = 2/125 (1%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH A+ +G A V+ L + + T LHLAA +V+ + L +H+ Sbjct: 236 LHTASAAGFAKCVQLLLSHNADVRSQFGEGKVTALHLAAENDYVECARLLLEHRAEVDCR 295 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFA--AQNSHLELVKYLVR 548 +H A + V L++ GA+V A R G TALH A Q+ L+ L++ Sbjct: 296 NASHQTPLHLACLSQSIGTVDLLISYGANVNAVYRDGRTALHAAIVKQSRSLDCCNALLK 355 Query: 549 RGVDI 563 G D+ Sbjct: 356 AGADV 360 Score = 47.4 bits (111), Expect = 3e-05 Identities = 36/126 (28%), Positives = 50/126 (39%), Gaps = 2/126 (1%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AA + D L ++ R+ +TPLHLA + + V L + Sbjct: 270 LHLAAEN-DYVECARLLLEHRAEVDCRNASHQTPLHLACLSQSIGTVDLLISYGANVNAV 328 Query: 375 XXXXXXXIHFA--SQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVR 548 +H A Q L+ LL +GA V + G+T LH AA N V + Sbjct: 329 YRDGRTALHAAIVKQSRSLDCCNALLKAGADVNKADNYGYTPLHIAALNEFSSCVYTFIE 388 Query: 549 RGVDIT 566 G DIT Sbjct: 389 HGADIT 394 Score = 34.7 bits (78), Expect = 0.20 Identities = 29/109 (26%), Positives = 47/109 (43%), Gaps = 1/109 (0%) Frame = +3 Query: 246 DSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXX-XXXXXXXXXXXIHFASQKGH 422 ++DP +SR RTPLH A + + K L +H A+ Sbjct: 123 NADPNVADSR---GRTPLHFACCRANAPIAKVLLDFGADPNRWDARKEVTSLHCAASSKS 179 Query: 423 LEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDITT 569 +E + LL AS+ K +ALH+A + ++ V+ L++ G D T Sbjct: 180 VECILLLLRRKASINIGIEKR-SALHYAIDVNAVDCVEILLKYGADPNT 227
>V018_FOWPV (Q9J5I3) Putative ankyrin repeat protein FPV018| Length = 700 Score = 48.5 bits (114), Expect = 1e-05 Identities = 28/100 (28%), Positives = 47/100 (47%) Frame = +3 Query: 264 LNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVREL 443 +N R+R +TP+HLA + +K L K+ + S++G + + L Sbjct: 422 VNVRNRYGKTPIHLACMYSKIGNIKVLIKNGANVNERDNYGITPLMICSREGKVSNMEYL 481 Query: 444 LASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 LA+GA V + TAL +A +N E + L+ G D+ Sbjct: 482 LANGADVNQTDYDKNTALTYAIRNKSKECTRVLLEHGADM 521 Score = 36.2 bits (82), Expect = 0.067 Identities = 18/56 (32%), Positives = 28/56 (50%) Frame = +3 Query: 396 IHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 IH A + R L+ GA V +NR G T +H A S + +K L++ G ++ Sbjct: 400 IHAAVSINTSRLTRLLINKGADVNVRNRYGKTPIHLACMYSKIGNIKVLIKNGANV 455 Score = 29.3 bits (64), Expect = 8.2 Identities = 25/125 (20%), Positives = 48/125 (38%) Frame = +3 Query: 189 LKLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXX 368 L LH + + + L +SD +N D PLH+A +++V+ L + Sbjct: 32 LSLHNILKENNVDRLRELIESDKDVINMYDSNRLLPLHIAIEHSDIEIVEMLLDNNAVIN 91 Query: 369 XXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVR 548 I+ A L R +L + +++ L + ++VK L++ Sbjct: 92 GGETIKTHPINIAM---ILAGGRMMLYNDNKPVKPSKRIRRLLTVNNTEKYTKIVKLLIK 148 Query: 549 RGVDI 563 G D+ Sbjct: 149 HGADL 153
>YR845_MIMIV (Q5UP14) Putative ankyrin repeat protein R845| Length = 224 Score = 48.5 bits (114), Expect = 1e-05 Identities = 37/126 (29%), Positives = 62/126 (49%), Gaps = 1/126 (0%) Frame = +3 Query: 186 DLKLHKAARSGDAAAVESLCDSDPLALNSRDRLSR-TPLHLAAWAGHVDVVKCLCKHKXX 362 D + KA+++G VE L + L + R+ + + A+ GH+ V+ L Sbjct: 77 DKAVRKASKNGRLEIVEYL-----VTLGADIRIDNDSAVRWASKNGHIKTVEFLV---AK 128 Query: 363 XXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYL 542 + +S+ GH+++V L+A GA V+A N A+ +A+ HLE+VKYL Sbjct: 129 GADIRAKNDYSLRHSSKHGHIKMVEYLVAQGADVRADNDY---AIKWASGKGHLEVVKYL 185 Query: 543 VRRGVD 560 V +G D Sbjct: 186 VEKGAD 191 Score = 47.8 bits (112), Expect = 2e-05 Identities = 33/126 (26%), Positives = 64/126 (50%) Frame = +3 Query: 186 DLKLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXX 365 D L +A+R+G V+ L + + D+ R A+ G +++V+ L Sbjct: 47 DYILLRASRNGYIDVVKYLIEQGVDPRTNNDKAVRK----ASKNGRLEIVEYLV---TLG 99 Query: 366 XXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLV 545 + +AS+ GH++ V L+A GA ++AKN +L ++++ H+++V+YLV Sbjct: 100 ADIRIDNDSAVRWASKNGHIKTVEFLVAKGADIRAKND---YSLRHSSKHGHIKMVEYLV 156 Query: 546 RRGVDI 563 +G D+ Sbjct: 157 AQGADV 162 Score = 44.3 bits (103), Expect = 2e-04 Identities = 24/53 (45%), Positives = 35/53 (66%) Frame = +3 Query: 396 IHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 I +AS KGHLEVV+ L+ GA +A N A+ +A+Q +E+V+YLV +G Sbjct: 170 IKWASGKGHLEVVKYLVEKGADFRADND---CAVKWASQTGRVEIVEYLVSKG 219 Score = 37.4 bits (85), Expect = 0.030 Identities = 20/64 (31%), Positives = 38/64 (59%), Gaps = 6/64 (9%) Frame = +3 Query: 396 IHFASQKGHLEVVRELLASGASVKAKNRKGFTALHF------AAQNSHLELVKYLVRRGV 557 I A + GHL+V++ L++ G+ V ++H+ A++N ++++VKYL+ +GV Sbjct: 20 IKSAFENGHLQVIKYLISLGSDV---------SMHYDYILLRASRNGYIDVVKYLIEQGV 70 Query: 558 DITT 569 D T Sbjct: 71 DPRT 74 Score = 30.0 bits (66), Expect = 4.8 Identities = 15/46 (32%), Positives = 28/46 (60%) Frame = +3 Query: 429 VVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDIT 566 +V L++ GA V++ A+ A +N HL+++KYL+ G D++ Sbjct: 1 MVEYLVSLGADVRSNYDH---AIKSAFENGHLQVIKYLISLGSDVS 43
>NFKB1_RAT (Q63369) Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor| KBF1) (EBP-1) [Contains: Nuclear factor NF-kappa-B p50 subunit] (Fragment) Length = 522 Score = 48.5 bits (114), Expect = 1e-05 Identities = 33/118 (27%), Positives = 57/118 (48%), Gaps = 3/118 (2%) Frame = +3 Query: 219 DAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXI 398 D V S SD + +N R+ L +TPLHLA DVV+ L + + Sbjct: 108 DLLEVTSGSISDDI-INMRNDLYQTPLHLAVITKQEDVVEDLLRVGADLSLLDRWGNSVL 166 Query: 399 HFASQKGHLEVVRELLASGAS---VKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 H A+++GH +++ LL + + + N +G A+H A ++ L ++ LV G ++ Sbjct: 167 HLAAKEGHDKILGVLLKNSKAALLINHPNGEGLNAIHIAVMSNSLSCLQLLVAAGAEV 224
>AKR1_GIBZE (Q4I8B6) Palmitoyltransferase AKR1 (EC 2.3.1.-) (Ankyrin| repeat-containing protein AKR1) Length = 702 Score = 48.5 bits (114), Expect = 1e-05 Identities = 33/122 (27%), Positives = 53/122 (43%), Gaps = 1/122 (0%) Frame = +3 Query: 201 KAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXX 380 + AR GD A+E L +S D TPLH AA + K L +H Sbjct: 34 QVARVGDVPAMEKLFESGEYDATYHDDEGITPLHWAAINNQYAMCKFLIEHGAEINRKGG 93 Query: 381 XXXXX-IHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGV 557 + +A+Q+ H V LL GA + +G+ LH + N ++ L+ L+ +G+ Sbjct: 94 ESIATPLQWAAQRCHYYTVNLLLQHGADPLVTDAQGYNTLHISTFNGNVLLLVLLLHQGI 153 Query: 558 DI 563 + Sbjct: 154 PV 155 Score = 39.3 bits (90), Expect = 0.008 Identities = 28/104 (26%), Positives = 47/104 (45%) Frame = +3 Query: 249 SDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLE 428 +DPL +++ LH++ + G+V ++ L + +A+ KG + Sbjct: 120 ADPLVTDAQ---GYNTLHISTFNGNVLLLVLLLHQGIPVDVIDTFGHTALMWAAYKGFPQ 176 Query: 429 VVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVD 560 V L GASV A + +GFTALH+A + L+ G D Sbjct: 177 CVDLFLRWGASVHATDEQGFTALHWALVKGSPGCILKLIEYGAD 220
>BCOR_MOUSE (Q8CGN4) BCoR protein (BCL-6 corepressor)| Length = 1759 Score = 48.5 bits (114), Expect = 1e-05 Identities = 33/93 (35%), Positives = 43/93 (46%), Gaps = 1/93 (1%) Frame = +3 Query: 291 TPLHLAAWAGHVDVVK-CLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVK 467 T L AA G+ +VV CL +H A +G L +VR LL GA V Sbjct: 1469 TLLQRAARLGYEEVVLYCLENKVCDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVN 1528 Query: 468 AKNRKGFTALHFAAQNSHLELVKYLVRRGVDIT 566 + G LH A +N HLE+V+ L+ G D T Sbjct: 1529 CSAQDGTRPLHDAVENDHLEIVRLLLSYGADPT 1561 Score = 41.2 bits (95), Expect = 0.002 Identities = 31/114 (27%), Positives = 50/114 (43%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 L +AAR G V ++ +N RD LH A G +++V+ L ++ Sbjct: 1471 LQRAARLGYEEVVLYCLENKVCDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVNCS 1530 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVK 536 +H A + HLE+VR LL+ GA G T + + +H EL++ Sbjct: 1531 AQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIM----KMTHSELME 1580
>V244_FOWPV (Q9J4Z6) Putative ankyrin repeat protein FPV244| Length = 668 Score = 48.5 bits (114), Expect = 1e-05 Identities = 30/102 (29%), Positives = 52/102 (50%), Gaps = 2/102 (1%) Frame = +3 Query: 264 LNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEV-VRE 440 +N+RD +TP+H AA +V ++ L + +HFA + + V+ Sbjct: 368 VNARDYCDKTPIHYAAVRNNVVIINTLLDYGADIEALSQKIGTVLHFALYGTNPYMSVKT 427 Query: 441 LLASGASVKAKNRKGFTALHFAA-QNSHLELVKYLVRRGVDI 563 L+ GA+V +KN+ T LH+A +N E++K L+ G D+ Sbjct: 428 LIDRGANVNSKNKYLSTPLHYACKKNCKPEVIKMLLDNGADV 469 Score = 43.1 bits (100), Expect = 5e-04 Identities = 30/104 (28%), Positives = 53/104 (50%), Gaps = 2/104 (1%) Frame = +3 Query: 264 LNSRDRLSRTPLHLAAWAG-HVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRE 440 +N+ D L TPLH A+ + D V L + IH+A+ + ++ ++ Sbjct: 334 VNAADSLYITPLHQASTLDRYKDTVITLLELGANVNARDYCDKTPIHYAAVRNNVVIINT 393 Query: 441 LLASGASVKAKNRKGFTALHFAAQNSHLEL-VKYLVRRGVDITT 569 LL GA ++A ++K T LHFA ++ + VK L+ RG ++ + Sbjct: 394 LLDYGADIEALSQKIGTVLHFALYGTNPYMSVKTLIDRGANVNS 437 Score = 32.3 bits (72), Expect = 0.97 Identities = 16/51 (31%), Positives = 27/51 (52%) Frame = +3 Query: 411 QKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 Q+ L + LL G V AK+ T +H+AA+ + ++V L+ G D+ Sbjct: 154 QQDELLIAEMLLKKGIDVNAKDVYCRTPIHYAAERGNTKMVNLLLSYGADV 204
>IASPP_CAEEL (Q9XVN3) Apoptotic enhancer 1 protein (Inhibitor member of the ASPP| family) (Protein iASPP) (Ce-iASPP) Length = 769 Score = 48.5 bits (114), Expect = 1e-05 Identities = 31/98 (31%), Positives = 48/98 (48%), Gaps = 3/98 (3%) Frame = +3 Query: 270 SRDRLSRTPLHL---AAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRE 440 ++ R+ PL L AA G +D+V+ +H A GH E+VR Sbjct: 545 NKGRIEFDPLALLLDAALEGELDLVRSSASKLTDVSQANDEGITALHNAICAGHYEIVRF 604 Query: 441 LLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 L+ + A V A++ G+T LH AA ++L +V+ LV G Sbjct: 605 LIENDADVNAQDSDGWTPLHCAASCNNLPMVRQLVEGG 642 Score = 38.1 bits (87), Expect = 0.018 Identities = 18/53 (33%), Positives = 29/53 (54%) Frame = +3 Query: 405 ASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 A+ +G L++VR + V N +G TALH A H E+V++L+ D+ Sbjct: 560 AALEGELDLVRSSASKLTDVSQANDEGITALHNAICAGHYEIVRFLIENDADV 612
>ASB3_HUMAN (Q9Y575) Ankyrin repeat and SOCS box protein 3 (ASB-3)| Length = 518 Score = 48.5 bits (114), Expect = 1e-05 Identities = 33/127 (25%), Positives = 59/127 (46%), Gaps = 3/127 (2%) Frame = +3 Query: 189 LKLHKAARSGDAAAVESL--CDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXX 362 + +H+AA ++ L DS + + LHLAA GH +V+ L + Sbjct: 45 MPIHEAAYHNSVECLQMLINADSSENYIKMKTFEGFCALHLAASQGHWKIVQILLEAGAD 104 Query: 363 XXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRK-GFTALHFAAQNSHLELVKY 539 + A + G ++V+R LL GA+V + G+ +LH A+ + E++K Sbjct: 105 PNATTLEETTPLFLAVENGQIDVLRLLLQHGANVNGSHSMCGWNSLHQASFQENAEIIKL 164 Query: 540 LVRRGVD 560 L+R+G + Sbjct: 165 LLRKGAN 171 Score = 43.5 bits (101), Expect = 4e-04 Identities = 28/123 (22%), Positives = 56/123 (45%), Gaps = 3/123 (2%) Frame = +3 Query: 204 AARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXX 383 AAR G+ + L +++ D P+H AA+ V+ ++ L Sbjct: 17 AAREGNVKVLRKLLKKGR-SVDVADNRGWMPIHEAAYHNSVECLQMLINADSSENYIKMK 75 Query: 384 XXX---XIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 +H A+ +GH ++V+ LL +GA A + T L A +N +++++ L++ G Sbjct: 76 TFEGFCALHLAASQGHWKIVQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHG 135 Query: 555 VDI 563 ++ Sbjct: 136 ANV 138 Score = 41.6 bits (96), Expect = 0.002 Identities = 25/88 (28%), Positives = 42/88 (47%) Frame = +3 Query: 297 LHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKN 476 LH A++ + +++K L + + A+Q G LE + L++SGA+V + Sbjct: 150 LHQASFQENAEIIKLLLRKGANKECQDDFGITPLFVAAQYGKLESLSILISSGANVNCQA 209 Query: 477 RKGFTALHFAAQNSHLELVKYLVRRGVD 560 T L AAQ H + V+ L+ G D Sbjct: 210 LDKATPLFIAAQEGHTKCVELLLSSGAD 237 Score = 34.7 bits (78), Expect = 0.20 Identities = 24/93 (25%), Positives = 40/93 (43%), Gaps = 2/93 (2%) Frame = +3 Query: 273 RDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLAS 452 +D TPL +AA G ++ + L + A+Q+GH + V LL+S Sbjct: 175 QDDFGITPLFVAAQYGKLESLSILISSGANVNCQALDKATPLFIAAQEGHTKCVELLLSS 234 Query: 453 GA--SVKAKNRKGFTALHFAAQNSHLELVKYLV 545 GA + +H AAQ H +++ L+ Sbjct: 235 GADPDLYCNEDSWQLPIHAAAQMGHTKILDLLI 267
>ANR15_HUMAN (Q14678) Ankyrin repeat domain-containing protein 15 (Kidney ankyrin| repeat-containing protein) Length = 1352 Score = 48.1 bits (113), Expect = 2e-05 Identities = 33/122 (27%), Positives = 60/122 (49%), Gaps = 5/122 (4%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAG-----HVDVVKCLCKHKX 359 LH + + V+ L D+D ++ +++ TP+ LAA A + +V+ L Sbjct: 1166 LHYSVSHSNFEIVKLLLDADVCNVDHQNKAGYTPIMLAALAAVEAEKDMRIVEELFGCGD 1225 Query: 360 XXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKY 539 + A G +++V+ LLA GA V ++ +G TAL A+++ H+E+VK Sbjct: 1226 VNAKASQAGQTALMLAVSHGRIDMVKGLLACGADVNIQDDEGSTALMCASEHGHVEIVKL 1285 Query: 540 LV 545 L+ Sbjct: 1286 LL 1287 Score = 37.7 bits (86), Expect = 0.023 Identities = 26/86 (30%), Positives = 40/86 (46%), Gaps = 1/86 (1%) Frame = +3 Query: 288 RTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLAS-GASV 464 +T L LA G +D+VK L + AS+ GH+E+V+ LLA G + Sbjct: 1235 QTALMLAVSHGRIDMVKGLLACGADVNIQDDEGSTALMCASEHGHVEIVKLLLAQPGCNG 1294 Query: 465 KAKNRKGFTALHFAAQNSHLELVKYL 542 ++ G TAL A + H ++ L Sbjct: 1295 HLEDNDGSTALSIALEAGHKDIAVLL 1320 Score = 31.6 bits (70), Expect = 1.7 Identities = 30/128 (23%), Positives = 48/128 (37%), Gaps = 9/128 (7%) Frame = +3 Query: 207 ARSGDAAAVESLCDSDPL--ALNSRDRLSRTPLHLAAWAGHVDVVK-------CLCKHKX 359 A GD A D L +N D T LH + + ++VK C H+ Sbjct: 1134 AMVGDYIAAFEAISPDVLRYVINLADGNGNTALHYSVSHSNFEIVKLLLDADVCNVDHQN 1193 Query: 360 XXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKY 539 ++K + +V EL G ++ G TAL A + +++VK Sbjct: 1194 KAGYTPIMLAALAAVEAEKD-MRIVEELFGCGDVNAKASQAGQTALMLAVSHGRIDMVKG 1252 Query: 540 LVRRGVDI 563 L+ G D+ Sbjct: 1253 LLACGADV 1260
>BCL3_HUMAN (P20749) B-cell lymphoma 3-encoded protein (Protein Bcl-3)| Length = 446 Score = 48.1 bits (113), Expect = 2e-05 Identities = 41/133 (30%), Positives = 54/133 (40%), Gaps = 7/133 (5%) Frame = +3 Query: 186 DLKLHKAARSGDAAAVESLCD---SDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHK 356 D LH A G+ AV L + L+ + L +TPLHLA VV+ L Sbjct: 128 DTPLHIAVVQGNLPAVHRLVNLFQQGGRELDIYNNLRQTPLHLAVITTLPSVVRLLVTAG 187 Query: 357 XXXXXXXXXXXXXIHFASQKGHLEVVRELLASGA----SVKAKNRKGFTALHFAAQNSHL 524 H A + +R LL S A ++A+N G TALH A Sbjct: 188 ASPMALDRHGQTAAHLACEHRSPTCLRALLDSAAPGTLDLEARNYDGLTALHVAVNTECQ 247 Query: 525 ELVKYLVRRGVDI 563 E V+ L+ RG DI Sbjct: 248 ETVQLLLERGADI 260 Score = 40.0 bits (92), Expect = 0.005 Identities = 38/126 (30%), Positives = 54/126 (42%), Gaps = 5/126 (3%) Frame = +3 Query: 198 HKAARSGDAAAVESLCDS---DPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXX 368 H A + +L DS L L +R+ T LH+A + V+ L + Sbjct: 202 HLACEHRSPTCLRALLDSAAPGTLDLEARNYDGLTALHVAVNTECQETVQLLLERGADID 261 Query: 369 XXXXXXXXX--IHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYL 542 IH A + L +V+ LL GA+V A+ G +ALH A+ L LV+ L Sbjct: 262 AVDIKSGRSPLIH-AVENNSLSMVQLLLQHGANVNAQMYSGSSALHSASGRGLLPLVRTL 320 Query: 543 VRRGVD 560 VR G D Sbjct: 321 VRSGAD 326
>BCOR_HUMAN (Q6W2J9) BCoR protein (BCL-6 corepressor)| Length = 1755 Score = 48.1 bits (113), Expect = 2e-05 Identities = 33/93 (35%), Positives = 43/93 (46%), Gaps = 1/93 (1%) Frame = +3 Query: 291 TPLHLAAWAGHVDVVK-CLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVK 467 T L AA G+ +VV CL +H A +G L +VR LL GA V Sbjct: 1465 TLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVN 1524 Query: 468 AKNRKGFTALHFAAQNSHLELVKYLVRRGVDIT 566 + G LH A +N HLE+V+ L+ G D T Sbjct: 1525 CSAQDGTRPLHDAVENDHLEIVRLLLSYGADPT 1557 Score = 40.8 bits (94), Expect = 0.003 Identities = 31/114 (27%), Positives = 50/114 (43%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 L +AAR G V ++ +N RD LH A G +++V+ L ++ Sbjct: 1467 LQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVNCS 1526 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVK 536 +H A + HLE+VR LL+ GA G T + + +H EL++ Sbjct: 1527 AQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIM----KMTHSELME 1576
>ASZ1_HORSE (Q2QLA4) Ankyrin repeat, SAM and basic leucine zipper| domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein) Length = 475 Score = 48.1 bits (113), Expect = 2e-05 Identities = 31/99 (31%), Positives = 46/99 (46%) Frame = +3 Query: 246 DSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHL 425 ++DP N R TP+ AA GH VV L H + +A+++GH Sbjct: 139 NADP---NVACRRLMTPIMYAARDGHPQVVALLVAHGAEVNTQDENGYTALTWAARQGHK 195 Query: 426 EVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYL 542 VV +LL GA+ + + G T A +N HLE+ +L Sbjct: 196 NVVLKLLELGANKMLQTKDGKTPSEIAKRNKHLEIFNFL 234 Score = 48.1 bits (113), Expect = 2e-05 Identities = 43/157 (27%), Positives = 65/157 (41%), Gaps = 37/157 (23%) Frame = +3 Query: 201 KAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLC---------KH 353 +A +GD A VE L DS ++++S R TPL AA +VD+V+ L K Sbjct: 52 RALTAGDVALVEELLDSG-ISVDSSFRYGWTPLMYAASVSNVDLVRVLLDRGAKASFDKD 110 Query: 354 KXXXXXXXXXXXXX----------------------------IHFASQKGHLEVVRELLA 449 K I +A++ GH +VV L+A Sbjct: 111 KQTILITACSARGSEEQILKCVELLLSRNADPNVACRRLMTPIMYAARDGHPQVVALLVA 170 Query: 450 SGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVD 560 GA V ++ G+TAL +AA+ H +V L+ G + Sbjct: 171 HGAEVNTQDENGYTALTWAARQGHKNVVLKLLELGAN 207
>ASZ1_BOVIN (Q8WMX8) Ankyrin repeat, SAM and basic leucine zipper| domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein) Length = 475 Score = 48.1 bits (113), Expect = 2e-05 Identities = 31/99 (31%), Positives = 46/99 (46%) Frame = +3 Query: 246 DSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHL 425 ++DP N R TP+ AA GH VV L H + +A+++GH Sbjct: 139 NADP---NVACRRLMTPIMYAARDGHPQVVALLVAHGAEVNTQDENGYTALTWAARQGHK 195 Query: 426 EVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYL 542 VV +LL GA+ + + G T A +N HLE+ +L Sbjct: 196 NVVLKLLELGANKMIQTKDGKTPSEIAKRNKHLEIFNFL 234 Score = 42.4 bits (98), Expect = 0.001 Identities = 21/55 (38%), Positives = 34/55 (61%) Frame = +3 Query: 396 IHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVD 560 I +A++ GH +VV L+A GA V ++ G+TAL +AA+ H +V L+ G + Sbjct: 153 IMYAARDGHPQVVALLVAHGAEVNTQDENGYTALTWAARQGHKNVVLKLLELGAN 207 Score = 41.2 bits (95), Expect = 0.002 Identities = 21/48 (43%), Positives = 33/48 (68%) Frame = +3 Query: 417 GHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVD 560 G++ +V ELL SG SV + G+T+L +AA S++ELV+ L+ RG + Sbjct: 57 GNISLVEELLDSGISVDTSFQYGWTSLMYAASVSNVELVRVLLDRGAN 104
>ACBD6_MOUSE (Q9D061) Acyl-CoA-binding domain-containing protein 6| Length = 282 Score = 47.8 bits (112), Expect = 2e-05 Identities = 22/57 (38%), Positives = 37/57 (64%) Frame = +3 Query: 396 IHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDIT 566 +H+A +GH E+V+ LL A + ++ +G TALH+AA L++V+ L++ G D T Sbjct: 196 LHWACDRGHKELVKVLLQYEAGINCQDNEGQTALHYAAACEFLDIVELLLQSGADPT 252 Score = 37.7 bits (86), Expect = 0.023 Identities = 24/100 (24%), Positives = 41/100 (41%) Frame = +3 Query: 186 DLKLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXX 365 D + R + + S +N D R LH A GH ++VK L +++ Sbjct: 159 DKNIFDYCRENNIDHIAKAIKSKAADVNMTDEEGRALLHWACDRGHKELVKVLLQYEAGI 218 Query: 366 XXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKG 485 +H+A+ L++V LL SGA +++ G Sbjct: 219 NCQDNEGQTALHYAAACEFLDIVELLLQSGADPTLRDQDG 258
>YL062_MIMIV (Q5UPE3) Putative ankyrin repeat protein L62| Length = 252 Score = 47.4 bits (111), Expect = 3e-05 Identities = 26/85 (30%), Positives = 43/85 (50%) Frame = +3 Query: 306 AAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKG 485 A + GH++++K L I +S G++E+V+ L+ G V+ N Sbjct: 23 ACYGGHLEIIKYLVSQ---GADVRYDDDMNISISSMTGNIEIVKYLVTQGCDVRTGNNH- 78 Query: 486 FTALHFAAQNSHLELVKYLVRRGVD 560 A+ +A N HLE+VKYL+ +G D Sbjct: 79 --AIRWACGNGHLEVVKYLMSQGAD 101 Score = 45.4 bits (106), Expect = 1e-04 Identities = 27/89 (30%), Positives = 44/89 (49%) Frame = +3 Query: 297 LHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKN 476 + +++ G++++VK L I +A GHLEVV+ L++ GA + Sbjct: 50 ISISSMTGNIEIVKYLVTQ---GCDVRTGNNHAIRWACGNGHLEVVKYLMSQGADTSVYD 106 Query: 477 RKGFTALHFAAQNSHLELVKYLVRRGVDI 563 L +A N H E+VKYL+ +G DI Sbjct: 107 NY---VLCWAVTNKHFEIVKYLISQGTDI 132 Score = 42.7 bits (99), Expect = 7e-04 Identities = 21/55 (38%), Positives = 36/55 (65%) Frame = +3 Query: 396 IHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVD 560 I AS+ GH+EVV+ L++ GA +A++ A+ +A++N + E+V YL +G D Sbjct: 170 IKMASKNGHIEVVKYLVSQGADFRAEDN---FAVRWASRNGYFEVVYYLTSQGAD 221 Score = 40.4 bits (93), Expect = 0.004 Identities = 18/58 (31%), Positives = 35/58 (60%) Frame = +3 Query: 396 IHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDITT 569 + +A GHLE+++ L++ GA V+ + + ++ ++E+VKYLV +G D+ T Sbjct: 20 VQYACYGGHLEIIKYLVSQGADVRYDDDMN---ISISSMTGNIEIVKYLVTQGCDVRT 74 Score = 40.0 bits (92), Expect = 0.005 Identities = 20/55 (36%), Positives = 36/55 (65%) Frame = +3 Query: 396 IHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVD 560 I AS+ G++E+V+ + GA+ + ++ A+ A++N H+E+VKYLV +G D Sbjct: 140 IKSASENGYIEMVKYFVYLGANFRDEDD---CAIKMASKNGHIEVVKYLVSQGAD 191 Score = 32.7 bits (73), Expect = 0.74 Identities = 15/45 (33%), Positives = 26/45 (57%) Frame = +3 Query: 429 VVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 +V+ L++ G + G A+ +A HLE++KYLV +G D+ Sbjct: 1 MVKYLVSKGCDISLI---GDVAVQYACYGGHLEIIKYLVSQGADV 42
>AKR1_MORAP (Q9UVH3) Palmitoyltransferase AKR1 (EC 2.3.1.-) (Ankyrin| repeat-containing protein AKR1) (Fragment) Length = 559 Score = 47.4 bits (111), Expect = 3e-05 Identities = 30/99 (30%), Positives = 48/99 (48%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH A S +A V L + + +++ D L T L AA+ G V+ L KH Sbjct: 13 LHLATHSSNAMLVLYLLMAGEMPVDTADTLGHTSLMWAAYQGDSLSVQILLKHGARVDTK 72 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFT 491 +H+A KG+ E + ++L +GA +KA ++ G T Sbjct: 73 DREGFTPLHWAVVKGNRECLSKILMAGADIKAGDKSGKT 111
>POTE2_HUMAN (Q6S8J3) Prostate, ovary, testis expressed protein on chromosome 2| (Fragment) Length = 712 Score = 47.4 bits (111), Expect = 3e-05 Identities = 36/124 (29%), Positives = 51/124 (41%) Frame = +3 Query: 192 KLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXX 371 KLH+AA G + + +N +D+ RT LHLA+ G+ +VVK L + Sbjct: 142 KLHRAAWWGKVPRKDLIVMLRDTDVNKKDKQKRTALHLASANGNSEVVKLLLDRRCQLNV 201 Query: 372 XXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRR 551 + A Q E LL G + G T LH+A N + K L+ Sbjct: 202 LDNKKRTALIKAVQCQEDECALMLLEHGTDPNIPDEYGNTTLHYAIYNEDKLMAKALLLY 261 Query: 552 GVDI 563 G DI Sbjct: 262 GADI 265 Score = 44.3 bits (103), Expect = 2e-04 Identities = 30/123 (24%), Positives = 53/123 (43%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH A+ +G++ V+ L D LN D RT L A + L +H Sbjct: 177 LHLASANGNSEVVKLLLDRR-CQLNVLDNKKRTALIKAVQCQEDECALMLLEHGTDPNIP 235 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 +H+A + + LL GA +++KN+ G T L ++VK+L+++ Sbjct: 236 DEYGNTTLHYAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKK 295 Query: 555 VDI 563 ++ Sbjct: 296 ANL 298 Score = 30.4 bits (67), Expect = 3.7 Identities = 22/86 (25%), Positives = 33/86 (38%) Frame = +3 Query: 264 LNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVREL 443 + S+++ TPL L VVK L K K + A G +V L Sbjct: 265 IESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVSLL 324 Query: 444 LASGASVKAKNRKGFTALHFAAQNSH 521 L V +++ G TA +A + H Sbjct: 325 LEQNIDVSSQDLSGQTAREYAVSSHH 350 Score = 29.3 bits (64), Expect = 8.2 Identities = 26/118 (22%), Positives = 44/118 (37%), Gaps = 9/118 (7%) Frame = +3 Query: 243 CDSDPLAL---------NSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXX 395 C D AL N D T LH A + + K L + Sbjct: 216 CQEDECALMLLEHGTDPNIPDEYGNTTLHYAIYNEDKLMAKALLLYGADIESKNKHGLTP 275 Query: 396 IHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDITT 569 + + +VV+ L+ A++ A +R G TAL A +V L+ + +D+++ Sbjct: 276 LLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVSLLLEQNIDVSS 333
>ASB4_HUMAN (Q9Y574) Ankyrin repeat and SOCS box protein 4 (ASB-4)| Length = 426 Score = 47.4 bits (111), Expect = 3e-05 Identities = 36/122 (29%), Positives = 52/122 (42%), Gaps = 2/122 (1%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH + G + L D + +N R +TPLH+A +VD VK LC Sbjct: 79 LHLSVLFGHVECLLVLLDHNA-TINCRPN-GKTPLHVACEMANVDCVKILCDRGAKLNCY 136 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASV--KAKNRKGFTALHFAAQNSHLELVKYLVR 548 +HF + + ++L+ GA+V K N+ T LH AA ELV + V Sbjct: 137 SLSGHTALHFCTTPSSILCAKQLVWRGANVNMKTNNQDEETPLHTAAHFGLSELVAFYVE 196 Query: 549 RG 554 G Sbjct: 197 HG 198 Score = 43.1 bits (100), Expect = 5e-04 Identities = 27/91 (29%), Positives = 41/91 (45%) Frame = +3 Query: 291 TPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKA 470 T LHL+ GHV+ + L H +H A + +++ V+ L GA + Sbjct: 77 TGLHLSVLFGHVECLLVLLDHNATINCRPNGKTP-LHVACEMANVDCVKILCDRGAKLNC 135 Query: 471 KNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 + G TALHF S + K LV RG ++ Sbjct: 136 YSLSGHTALHFCTTPSSILCAKQLVWRGANV 166
>YL022_MIMIV (Q5UPA3) Putative ankyrin repeat protein L22| Length = 122 Score = 47.0 bits (110), Expect = 4e-05 Identities = 28/89 (31%), Positives = 48/89 (53%) Frame = +3 Query: 297 LHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKN 476 + LA+ G+++VVK L + +AS+ GHL VV+ L++ GA ++ N Sbjct: 8 VRLASRNGYIEVVKYLVS---IGADIKADDDYAVKWASRYGHLRVVKFLVSQGADIRVNN 64 Query: 477 RKGFTALHFAAQNSHLELVKYLVRRGVDI 563 A+ A++N H ++VKYLV + +I Sbjct: 65 DY---AVQLASENGHFDVVKYLVSQDANI 90 Score = 43.5 bits (101), Expect = 4e-04 Identities = 28/84 (33%), Positives = 44/84 (52%), Gaps = 3/84 (3%) Frame = +3 Query: 312 WA---GHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRK 482 WA GH+ VVK L + AS+ GH +VV+ L++ A+++A + Sbjct: 40 WASRYGHLRVVKFLVSQ---GADIRVNNDYAVQLASENGHFDVVKYLVSQDANIRADDDY 96 Query: 483 GFTALHFAAQNSHLELVKYLVRRG 554 A+ A+ N H+E+VKYLV +G Sbjct: 97 ---AVKLASVNGHVEVVKYLVSQG 117 Score = 30.8 bits (68), Expect = 2.8 Identities = 19/54 (35%), Positives = 26/54 (48%) Frame = +3 Query: 297 LHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGA 458 + LA+ GH DVVK L + AS GH+EVV+ L++ GA Sbjct: 68 VQLASENGHFDVVKYLVSQDANIRADDDYA---VKLASVNGHVEVVKYLVSQGA 118
>CDN2C_HUMAN (P42773) Cyclin-dependent kinase 6 inhibitor (p18-INK6)| (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c) Length = 168 Score = 47.0 bits (110), Expect = 4e-05 Identities = 32/119 (26%), Positives = 59/119 (49%) Frame = +3 Query: 192 KLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXX 371 +L AA GD + SL ++ + +N+++ RT L + G+ ++ + L Sbjct: 8 ELASAAARGDLEQLTSLLQNN-VNVNAQNGFGRTALQVMK-LGNPEIARRLLLRGANPDL 65 Query: 372 XXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVR 548 IH A++ G L+ ++ LL A V ++ +G LH AA+ HL +V++LV+ Sbjct: 66 KDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVK 124 Score = 41.6 bits (96), Expect = 0.002 Identities = 29/95 (30%), Positives = 44/95 (46%), Gaps = 1/95 (1%) Frame = +3 Query: 273 RDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLAS 452 +DR +H AA AG +D ++ L + + +H A+++GHL VV L+ Sbjct: 66 KDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKH 125 Query: 453 GAS-VKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 AS V +N KG TA A E+V + G Sbjct: 126 TASNVGHRNHKGDTACDLARLYGRNEVVSLMQANG 160 Score = 38.1 bits (87), Expect = 0.018 Identities = 29/89 (32%), Positives = 40/89 (44%), Gaps = 1/89 (1%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXX-XXX 371 +H AAR+G +++L + +N D PLHLAA GH+ VV+ L KH Sbjct: 74 IHDAARAGFLDTLQTLLEFQA-DVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGH 132 Query: 372 XXXXXXXXIHFASQKGHLEVVRELLASGA 458 A G EVV + A+GA Sbjct: 133 RNHKGDTACDLARLYGRNEVVSLMQANGA 161
>V155_FOWPV (Q9J5A7) Putative ankyrin repeat protein FPV115| Length = 542 Score = 47.0 bits (110), Expect = 4e-05 Identities = 29/105 (27%), Positives = 55/105 (52%), Gaps = 1/105 (0%) Frame = +3 Query: 258 LALNSRDRLSRTPLHLAAWAGH-VDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVV 434 L +N++D+ +T LH A + + ++ VK + K+ +H A + G L++ Sbjct: 243 LDINTKDKKGKTALHYACNSINCIETVKEIMKYGADINVKDREGLTPLHSACKYGDLKLS 302 Query: 435 RELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDITT 569 + L+ GA VK K T L+ A ++ ++ELVK+L+ + + T Sbjct: 303 KLLIEYGADVKVKTTS--TVLNLAVESGNVELVKFLIEKNPEFIT 345 Score = 33.5 bits (75), Expect = 0.44 Identities = 16/42 (38%), Positives = 27/42 (64%), Gaps = 1/42 (2%) Frame = +3 Query: 441 LLASGASVKAKNRKGFTALHFAAQNSH-LELVKYLVRRGVDI 563 L+ G + K++KG TALH+A + + +E VK +++ G DI Sbjct: 238 LIEIGLDINTKDKKGKTALHYACNSINCIETVKEIMKYGADI 279
>YL099_MIMIV (Q5UPH1) Putative ankyrin repeat protein L99| Length = 261 Score = 47.0 bits (110), Expect = 4e-05 Identities = 27/89 (30%), Positives = 50/89 (56%) Frame = +3 Query: 297 LHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKN 476 L +++ ++++VK L H +H+A+Q+G EVV+ L+ +GA+V A+ Sbjct: 56 LKYSSFKCNLELVKVLISH---GANIHSDRDLALHYAAQQGCFEVVKYLIKNGANVNARQ 112 Query: 477 RKGFTALHFAAQNSHLELVKYLVRRGVDI 563 +AL A + H E++KYL+ +G +I Sbjct: 113 N---SALIRACDSHHYEMIKYLIDKGANI 138 Score = 36.2 bits (82), Expect = 0.067 Identities = 29/93 (31%), Positives = 41/93 (44%), Gaps = 4/93 (4%) Frame = +3 Query: 297 LHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKN 476 LH AA G +VVK L K+ A H E+++ L+ GA++ AKN Sbjct: 86 LHYAAQQGCFEVVKYLIKNGANVNARQNSALIR---ACDSHHYEMIKYLIDKGANIHAKN 142 Query: 477 RKGFTALHFAAQNSHL----ELVKYLVRRGVDI 563 +F +NS L E+ YL+ G DI Sbjct: 143 -------NFCLRNSVLHHKWEIFTYLMNNGADI 168
>BCL3_MOUSE (Q9Z2F6) B-cell lymphoma 3-encoded protein homolog (Protein Bcl-3)| Length = 440 Score = 47.0 bits (110), Expect = 4e-05 Identities = 40/133 (30%), Positives = 53/133 (39%), Gaps = 7/133 (5%) Frame = +3 Query: 186 DLKLHKAARSGDAAAVESLCDSDPLALNSRD---RLSRTPLHLAAWAGHVDVVKCLCKHK 356 D LH A + AAV + L D L +TPLHLA D+V+ L Sbjct: 123 DTPLHIAVVQNNIAAVYRILSLFKLGSREVDVHNNLRQTPLHLAVITTLPDMVRLLVTAG 182 Query: 357 XXXXXXXXXXXXXIHFASQKGHLEVVRELLASGAS----VKAKNRKGFTALHFAAQNSHL 524 IH A + ++ LL S S ++ +N +G TALH A Sbjct: 183 ASPMALDRHGQTAIHLACEHRSPSCLQALLDSATSGSVDLEVRNYEGLTALHVAVNTGCQ 242 Query: 525 ELVKYLVRRGVDI 563 E V L+ RG DI Sbjct: 243 EAVLLLLERGADI 255 Score = 42.0 bits (97), Expect = 0.001 Identities = 38/127 (29%), Positives = 56/127 (44%), Gaps = 5/127 (3%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDS---DPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXX 365 +H A + +++L DS + L R+ T LH+A G + V L + Sbjct: 196 IHLACEHRSPSCLQALLDSATSGSVDLEVRNYEGLTALHVAVNTGCQEAVLLLLERGADI 255 Query: 366 XXXXXXXXXX--IHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKY 539 IH A + L +V+ LL GA+V A+ G +ALH A+ L LV+ Sbjct: 256 DAVDIKSGRSPLIH-AVENNSLNMVQLLLLHGANVNAQMYSGSSALHSASGRGLLPLVRT 314 Query: 540 LVRRGVD 560 LVR G D Sbjct: 315 LVRSGAD 321
>UACA_HUMAN (Q9BZF9) Uveal autoantigen with coiled-coil domains and ankyrin| repeats protein Length = 1416 Score = 46.6 bits (109), Expect = 5e-05 Identities = 32/124 (25%), Positives = 54/124 (43%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AA+ G A ++ L + D RT LH AA A ++ LC H Sbjct: 105 LHLAAKYGHALCLQKLLQYN-CPTEHADLQGRTALHDAAMADCPSSIQLLCDHGASVNAK 163 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 + A+Q + + L+ GA V +++++ TAL + + V+ L++ G Sbjct: 164 DVDGRTPLVLATQMSRPTICQLLIDRGADVNSRDKQNRTALMLGCEYGCRDAVEVLIKNG 223 Query: 555 VDIT 566 DI+ Sbjct: 224 ADIS 227 Score = 43.5 bits (101), Expect = 4e-04 Identities = 29/102 (28%), Positives = 45/102 (44%) Frame = +3 Query: 264 LNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVREL 443 + + D R LHLAA GH ++ L ++ +H A+ ++ L Sbjct: 94 ITTSDTAGRNALHLAAKYGHALCLQKLLQYNCPTEHADLQGRTALHDAAMADCPSSIQLL 153 Query: 444 LASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDITT 569 GASV AK+ G T L A Q S + + L+ RG D+ + Sbjct: 154 CDHGASVNAKDVDGRTPLVLATQMSRPTICQLLIDRGADVNS 195 Score = 43.5 bits (101), Expect = 4e-04 Identities = 29/126 (23%), Positives = 51/126 (40%) Frame = +3 Query: 186 DLKLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXX 365 D +L KAA GD V S+ + D R+ H+ G+++ + + H Sbjct: 35 DDRLMKAAERGDVEKVTSILAKKGVNPGKLDVEGRSVFHVVTSKGNLECLNAILIHGVDI 94 Query: 366 XXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLV 545 +H A++ GH +++LL + + +G TALH AA ++ L Sbjct: 95 TTSDTAGRNALHLAAKYGHALCLQKLLQYNCPTEHADLQGRTALHDAAMADCPSSIQLLC 154 Query: 546 RRGVDI 563 G + Sbjct: 155 DHGASV 160 Score = 30.4 bits (67), Expect = 3.7 Identities = 17/56 (30%), Positives = 30/56 (53%), Gaps = 1/56 (1%) Frame = +3 Query: 405 ASQKGHLEVVRELLAS-GASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDITT 569 A+++G +E V +LA G + + +G + H +LE + ++ GVDITT Sbjct: 41 AAERGDVEKVTSILAKKGVNPGKLDVEGRSVFHVVTSKGNLECLNAILIHGVDITT 96
>YR880_MIMIV (Q5UQX8) Putative ankyrin repeat protein R880| Length = 255 Score = 46.6 bits (109), Expect = 5e-05 Identities = 29/89 (32%), Positives = 49/89 (55%) Frame = +3 Query: 297 LHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKN 476 L LA G++++VK L K + AS++GHL++V+ L+ G +V+ K+ Sbjct: 115 LQLACKYGYLEIVKYLVKK---GANINTDDCYAVQLASREGHLKIVKYLVELGTNVR-KD 170 Query: 477 RKGFTALHFAAQNSHLELVKYLVRRGVDI 563 R A ++ +N+HL + KYLV G D+ Sbjct: 171 RD--LAFRWSVENNHLSVTKYLVELGSDV 197
>ASB10_MOUSE (Q91ZT7) Ankyrin repeat and SOCS box protein 10 (ASB-10)| Length = 467 Score = 46.6 bits (109), Expect = 5e-05 Identities = 28/91 (30%), Positives = 42/91 (46%) Frame = +3 Query: 291 TPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKA 470 TPLH+AA GH +V++ L + + +H A GH VR LL +GA Sbjct: 118 TPLHVAASRGHTEVLELLLRRRAKPDSAPGGRTA-LHEACSAGHAACVRVLLVAGADPNT 176 Query: 471 KNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 ++ G LH LE V+ L++ G + Sbjct: 177 LDQDGKRPLHLCRGPGILECVELLLKFGAQV 207 Score = 45.1 bits (105), Expect = 1e-04 Identities = 33/104 (31%), Positives = 50/104 (48%), Gaps = 3/104 (2%) Frame = +3 Query: 195 LHKAARSGDAAAVESL--CDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXX 368 LH+A +G AA V L +DP N+ D+ + PLHL G ++ V+ L K Sbjct: 152 LHEACSAGHAACVRVLLVAGADP---NTLDQDGKRPLHLCRGPGILECVELLLKFGAQVD 208 Query: 369 XXXXXXXXX-IHFASQKGHLEVVRELLASGASVKAKNRKGFTAL 497 +H A++ GH+E+ LL GA +N +G+T L Sbjct: 209 GRTEDEEETPLHIAARLGHVELADLLLRWGACPDVRNSEGWTPL 252 Score = 42.4 bits (98), Expect = 0.001 Identities = 41/127 (32%), Positives = 49/127 (38%), Gaps = 7/127 (5%) Frame = +3 Query: 195 LHKAARSGDAAAVESLC------DSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHK 356 LH AA G +E L DS P RT LH A AGH V+ L Sbjct: 120 LHVAASRGHTEVLELLLRRRAKPDSAPGG--------RTALHEACSAGHAACVRVLLVAG 171 Query: 357 XXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNR-KGFTALHFAAQNSHLELV 533 +H G LE V LL GA V + + T LH AA+ H+EL Sbjct: 172 ADPNTLDQDGKRPLHLCRGPGILECVELLLKFGAQVDGRTEDEEETPLHIAARLGHVELA 231 Query: 534 KYLVRRG 554 L+R G Sbjct: 232 DLLLRWG 238 Score = 32.7 bits (73), Expect = 0.74 Identities = 21/58 (36%), Positives = 28/58 (48%) Frame = +3 Query: 396 IHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDITT 569 +H A+ +GH EV+ LL A + G TALH A H V+ L+ G D T Sbjct: 120 LHVAASRGHTEVLELLLRRRAKPDSAPG-GRTALHEACSAGHAACVRVLLVAGADPNT 176 Score = 30.8 bits (68), Expect = 2.8 Identities = 15/37 (40%), Positives = 21/37 (56%) Frame = +3 Query: 396 IHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFA 506 +H A + GH VV+ LL+ G + A + G T LH A Sbjct: 298 LHLACRHGHSAVVQLLLSCGVNANAMDYGGHTPLHCA 334
>ASZ1_PANTR (Q8WMX6) Ankyrin repeat, SAM and basic leucine zipper| domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein) Length = 475 Score = 46.6 bits (109), Expect = 5e-05 Identities = 34/122 (27%), Positives = 53/122 (43%), Gaps = 3/122 (2%) Frame = +3 Query: 204 AARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKC---LCKHKXXXXXX 374 AA +A V L D A +D+ S +A ++KC L Sbjct: 86 AASVANAELVRVLLDRGANASFEKDKQSILITACSAHGSEEQILKCVELLLSRNADPNVA 145 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 I +A++ GH +VV L+A GA V ++ G+TAL +AA+ H +V L+ G Sbjct: 146 CRRLMTPIMYAARDGHTQVVALLVAHGAEVNTQDENGYTALTWAARQGHKNIVLKLLELG 205 Query: 555 VD 560 + Sbjct: 206 AN 207 Score = 42.0 bits (97), Expect = 0.001 Identities = 28/99 (28%), Positives = 43/99 (43%) Frame = +3 Query: 246 DSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHL 425 ++DP N R TP+ AA GH VV L H + +A+++GH Sbjct: 139 NADP---NVACRRLMTPIMYAARDGHTQVVALLVAHGAEVNTQDENGYTALTWAARQGHK 195 Query: 426 EVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYL 542 +V +LL GA+ + + G A +N H E+ L Sbjct: 196 NIVLKLLELGANKMLQTKDGKMPSEIAKRNKHHEIFNLL 234 Score = 37.7 bits (86), Expect = 0.023 Identities = 20/48 (41%), Positives = 32/48 (66%) Frame = +3 Query: 417 GHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVD 560 G + +V+ELL SG SV + + G+T L +AA ++ ELV+ L+ RG + Sbjct: 57 GDVSLVQELLDSGISVDSTFQYGWTPLMYAASVANAELVRVLLDRGAN 104
>ASZ1_HUMAN (Q8WWH4) Ankyrin repeat, SAM and basic leucine zipper| domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein) Length = 475 Score = 46.6 bits (109), Expect = 5e-05 Identities = 34/122 (27%), Positives = 53/122 (43%), Gaps = 3/122 (2%) Frame = +3 Query: 204 AARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKC---LCKHKXXXXXX 374 AA +A V L D A +D+ S +A ++KC L Sbjct: 86 AASVANAELVRVLLDRGANASFEKDKQSILITACSAHGSEEQILKCVELLLSRNADPNVA 145 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 I +A++ GH +VV L+A GA V ++ G+TAL +AA+ H +V L+ G Sbjct: 146 CRRLMTPIMYAARDGHTQVVALLVAHGAEVNTQDENGYTALTWAARQGHKNIVLKLLELG 205 Query: 555 VD 560 + Sbjct: 206 AN 207 Score = 42.0 bits (97), Expect = 0.001 Identities = 28/99 (28%), Positives = 43/99 (43%) Frame = +3 Query: 246 DSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHL 425 ++DP N R TP+ AA GH VV L H + +A+++GH Sbjct: 139 NADP---NVACRRLMTPIMYAARDGHTQVVALLVAHGAEVNTQDENGYTALTWAARQGHK 195 Query: 426 EVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYL 542 +V +LL GA+ + + G A +N H E+ L Sbjct: 196 NIVLKLLELGANKMLQTKDGKMPSEIAKRNKHHEIFNLL 234 Score = 38.1 bits (87), Expect = 0.018 Identities = 20/48 (41%), Positives = 32/48 (66%) Frame = +3 Query: 417 GHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVD 560 G + +V+ELL SG SV + + G+T L +AA ++ ELV+ L+ RG + Sbjct: 57 GDVSLVQELLDSGISVDSNFQYGWTPLMYAASVANAELVRVLLDRGAN 104
>NFKB1_MOUSE (P25799) Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor| KBF1) (EBP-1) (NF-kappa-B1 p84/NF-kappa-B1 p98) [Contains: Nuclear factor NF-kappa-B p50 subunit] Length = 971 Score = 46.6 bits (109), Expect = 5e-05 Identities = 34/118 (28%), Positives = 55/118 (46%), Gaps = 3/118 (2%) Frame = +3 Query: 219 DAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXI 398 D V S SD + +N R+ L +TPLHLA DVV+ L + + Sbjct: 557 DLLEVTSGLISDDI-INMRNDLYQTPLHLAVITKQEDVVEDLLRVGADLSLLDRWGNSVL 615 Query: 399 HFASQKGHLEVVRELLASGAS---VKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 H A+++GH ++ LL S + + N +G A+H A ++ L + LV G ++ Sbjct: 616 HLAAKEGHDRILSILLKSRKAAPLIDHPNGEGLNAIHIAVMSNSLPCLLLLVAAGAEV 673
>CDN2D_HUMAN (P55273) Cyclin-dependent kinase 4 inhibitor D (p19-INK4d)| Length = 166 Score = 46.6 bits (109), Expect = 5e-05 Identities = 29/92 (31%), Positives = 43/92 (46%) Frame = +3 Query: 267 NSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELL 446 N +D +P+H AA G +D +K L +H IH A Q+GH VV L Sbjct: 68 NVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVV-SFL 126 Query: 447 ASGASVKAKNRKGFTALHFAAQNSHLELVKYL 542 A+ + + ++ +G T L A Q +LV L Sbjct: 127 AAESDLHRRDARGLTPLELALQRGAQDLVDIL 158 Score = 35.4 bits (80), Expect = 0.11 Identities = 17/49 (34%), Positives = 26/49 (53%) Frame = +3 Query: 417 GHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 G + ELL GAS ++ G + +H AA+ L+ +K LV G D+ Sbjct: 52 GSTAIALELLKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADV 100
>ASB9_HUMAN (Q96DX5) Ankyrin repeat and SOCS box protein 9 (ASB-9)| Length = 294 Score = 46.6 bits (109), Expect = 5e-05 Identities = 37/123 (30%), Positives = 56/123 (45%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 +H+AA G ++ +L S A+N +PLH A GH+ VK L KH Sbjct: 40 MHEAAIHGHQLSLRNLI-SQGWAVNIITADHVSPLHEACLGGHLSCVKILLKHGAQVNGV 98 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 + A G + V LL GASV+ ++ + +H AA+ H+E V L+ G Sbjct: 99 TADWHTPLFNACVSGSWDCVNLLLQHGASVQPESDLA-SPIHEAARRGHVECVNSLIAYG 157 Query: 555 VDI 563 +I Sbjct: 158 GNI 160 Score = 35.0 bits (79), Expect = 0.15 Identities = 25/90 (27%), Positives = 40/90 (44%) Frame = +3 Query: 291 TPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKA 470 +P+H AA GHV+ V L + ++ A + V++LL SGA V Sbjct: 136 SPIHEAARRGHVECVNSLIAYGGNIDHKISHLGTPLYLACENQQRACVKKLLESGADVN- 194 Query: 471 KNRKGFTALHFAAQNSHLELVKYLVRRGVD 560 + + + LH A+ + EL L+ G D Sbjct: 195 QGKGQDSPLHAVARTASEELACLLMDFGAD 224
>CDN2C_MOUSE (Q60772) Cyclin-dependent kinase 6 inhibitor (p18-INK6)| (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c) Length = 168 Score = 46.6 bits (109), Expect = 5e-05 Identities = 32/119 (26%), Positives = 59/119 (49%) Frame = +3 Query: 192 KLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXX 371 +L AA GD + SL ++ + +N+++ RT L + G+ ++ + L Sbjct: 8 ELASAAARGDLEQLTSLLQNN-VNVNAQNGFGRTALQVMK-LGNPEIARRLLLRGANPNL 65 Query: 372 XXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVR 548 IH A++ G L+ V+ LL A V ++ +G LH AA+ HL +V++L++ Sbjct: 66 KDGTGFAVIHDAARAGFLDTVQALLEFQADVNIEDNEGNLPLHLAAKEGHLPVVEFLMK 124 Score = 38.9 bits (89), Expect = 0.010 Identities = 22/53 (41%), Positives = 30/53 (56%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKH 353 +H AAR+G V++L + +N D PLHLAA GH+ VV+ L KH Sbjct: 74 IHDAARAGFLDTVQALLEFQA-DVNIEDNEGNLPLHLAAKEGHLPVVEFLMKH 125
>NFKB1_CHICK (Q04861) Nuclear factor NF-kappa-B p105 subunit [Contains: Nuclear| factor NF-kappa-B p50 subunit] Length = 984 Score = 46.6 bits (109), Expect = 5e-05 Identities = 28/103 (27%), Positives = 49/103 (47%), Gaps = 3/103 (2%) Frame = +3 Query: 264 LNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVREL 443 +N R+ L +TPLHLA +VV+ L K +H A+ +G +++ L Sbjct: 573 INMRNDLYQTPLHLAVITKQAEVVEDLLKAGANVNLLDRHGNSVLHLAAAEGDDKILSLL 632 Query: 444 L---ASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 L + + + N +G +A+H + L +K L+ GVD+ Sbjct: 633 LKHQKASSMIDLSNGEGLSAIHMVVTANSLSCLKLLIAAGVDV 675
>Y714_RICPR (Q9ZCL3) Hypothetical ANK-repeat protein RP714| Length = 107 Score = 46.6 bits (109), Expect = 5e-05 Identities = 24/85 (28%), Positives = 45/85 (52%) Frame = +3 Query: 291 TPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKA 470 +PL +A G+++ L ++ +H A+ KG+ ++ LL GA++ A Sbjct: 10 SPLIIAVLNGNIEYTSELLQNGVDIDVRDKNGNSALHIAASKGYTKIATMLLLYGATIDA 69 Query: 471 KNRKGFTALHFAAQNSHLELVKYLV 545 N + T LH+AA N++ +L +YL+ Sbjct: 70 PNFELATPLHYAAANNYKDLTQYLL 94 Score = 34.7 bits (78), Expect = 0.20 Identities = 15/49 (30%), Positives = 27/49 (55%) Frame = +3 Query: 417 GHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 G++E ELL +G + +++ G +ALH AA + ++ L+ G I Sbjct: 19 GNIEYTSELLQNGVDIDVRDKNGNSALHIAASKGYTKIATMLLLYGATI 67
>UACA_CANFA (Q9GL21) Uveal autoantigen with coiled-coil domains and ankyrin| repeats protein Length = 1415 Score = 46.2 bits (108), Expect = 6e-05 Identities = 30/126 (23%), Positives = 52/126 (41%) Frame = +3 Query: 186 DLKLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXX 365 D +L KAA GD V S+ + D R+ H+ A G+++ + + H Sbjct: 37 DDRLMKAAERGDVEKVSSILAKKGINPGKLDVEGRSAFHVVASKGNLECLNAILIHGVDI 96 Query: 366 XXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLV 545 +H A++ GH +++LL + + +G TALH AA ++ L Sbjct: 97 TTSDTAGRNALHLAAKYGHALCLQKLLQYNCPTEHADLQGRTALHDAAMADCPSSIQLLC 156 Query: 546 RRGVDI 563 G + Sbjct: 157 DHGASV 162 Score = 43.9 bits (102), Expect = 3e-04 Identities = 30/124 (24%), Positives = 54/124 (43%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AA+ G A ++ L + D RT LH AA A ++ LC H Sbjct: 107 LHLAAKYGHALCLQKLLQYN-CPTEHADLQGRTALHDAAMADCPSSIQLLCDHGASVNAK 165 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 + A+Q + + L+ GA + +++++ TAL + + V+ L++ G Sbjct: 166 DVDGRTPLVLATQMCRPAICQLLIDRGAEINSRDKQNRTALMLGCEYGCKDAVEVLLKNG 225 Query: 555 VDIT 566 D++ Sbjct: 226 ADVS 229 Score = 40.4 bits (93), Expect = 0.004 Identities = 28/102 (27%), Positives = 44/102 (43%) Frame = +3 Query: 264 LNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVREL 443 + + D R LHLAA GH ++ L ++ +H A+ ++ L Sbjct: 96 ITTSDTAGRNALHLAAKYGHALCLQKLLQYNCPTEHADLQGRTALHDAAMADCPSSIQLL 155 Query: 444 LASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDITT 569 GASV AK+ G T L A Q + + L+ RG +I + Sbjct: 156 CDHGASVNAKDVDGRTPLVLATQMCRPAICQLLIDRGAEINS 197 Score = 33.1 bits (74), Expect = 0.57 Identities = 19/56 (33%), Positives = 32/56 (57%), Gaps = 1/56 (1%) Frame = +3 Query: 405 ASQKGHLEVVRELLAS-GASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDITT 569 A+++G +E V +LA G + + +G +A H A +LE + ++ GVDITT Sbjct: 43 AAERGDVEKVSSILAKKGINPGKLDVEGRSAFHVVASKGNLECLNAILIHGVDITT 98
>DGK2_DROME (Q09103) Eye-specific diacylglycerol kinase (EC 2.7.1.107) (Retinal| degeneration A protein) (Diglyceride kinase 2) (DGK 2) (DAG kinase 2) Length = 1457 Score = 46.2 bits (108), Expect = 6e-05 Identities = 21/50 (42%), Positives = 34/50 (68%) Frame = +3 Query: 396 IHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLV 545 I A+Q G L ++R L G S+++ N+ G TALHFA + +H ++VKY++ Sbjct: 1325 ILLAAQSGDLNMLRALHEQGYSLQSVNKNGQTALHFACKYNHRDIVKYII 1374 Score = 39.3 bits (90), Expect = 0.008 Identities = 24/92 (26%), Positives = 43/92 (46%), Gaps = 3/92 (3%) Frame = +3 Query: 303 LAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGAS---VKAK 473 LAA +G +++++ L + +HFA + H ++V+ ++AS A Sbjct: 1327 LAAQSGDLNMLRALHEQGYSLQSVNKNGQTALHFACKYNHRDIVKYIIASATRRLINMAD 1386 Query: 474 NRKGFTALHFAAQNSHLELVKYLVRRGVDITT 569 G TALH AA+ + ++ LV G + T Sbjct: 1387 KELGQTALHIAAEQNRRDICVMLVAAGAHLDT 1418 Score = 37.4 bits (85), Expect = 0.030 Identities = 28/116 (24%), Positives = 52/116 (44%), Gaps = 3/116 (2%) Frame = +3 Query: 204 AARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCL---CKHKXXXXXX 374 AA+SGD + +L + +L S ++ +T LH A H D+VK + + Sbjct: 1328 AAQSGDLNMLRALHEQG-YSLQSVNKNGQTALHFACKYNHRDIVKYIIASATRRLINMAD 1386 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYL 542 +H A+++ ++ L+A+GA + + G T + A + E+ YL Sbjct: 1387 KELGQTALHIAAEQNRRDICVMLVAAGAHLDTLDSGGNTPMMVAFNKNANEIATYL 1442
>V245_FOWPV (Q9J4Z5) Putative ankyrin repeat protein FPV245| Length = 436 Score = 46.2 bits (108), Expect = 6e-05 Identities = 36/140 (25%), Positives = 56/140 (40%), Gaps = 23/140 (16%) Frame = +3 Query: 213 SGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXX 392 SGD + VE L + +N + TPL A G+ +V+ KH Sbjct: 11 SGDISLVEKLIKNKGNCINISVEETTTPLIDAIRTGNAKIVELFIKHGAQVNHVNTKIPN 70 Query: 393 XIHFASQKG-----------------------HLEVVRELLASGASVKAKNRKGFTALHF 503 + A + G + E+++ +L SG V KN K T LH+ Sbjct: 71 PLLTAIKIGSHDIVKLLLINGVDTSILPVPCINKEMIKTILDSGVKVNTKNAKSKTFLHY 130 Query: 504 AAQNSHLELVKYLVRRGVDI 563 A +N+ LE++K L G D+ Sbjct: 131 AIKNNDLEVIKMLFEYGADV 150 Score = 40.0 bits (92), Expect = 0.005 Identities = 17/53 (32%), Positives = 31/53 (58%) Frame = +3 Query: 396 IHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 +H+A + LEV++ L GA V K+ G +H A +++ E++K L+ +G Sbjct: 128 LHYAIKNNDLEVIKMLFEYGADVNIKDDNGCYPIHIATRSNSYEIIKLLLEKG 180 Score = 39.7 bits (91), Expect = 0.006 Identities = 32/125 (25%), Positives = 52/125 (41%), Gaps = 1/125 (0%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 +H A RS ++ L + A N +D +PLH AA G +K + H Sbjct: 161 IHIATRSNSYEIIKLLLEKGAYA-NVKDNYGNSPLHNAAKYGDYACIKLVLDHTNNISNK 219 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQ-NSHLELVKYLVRR 551 +H A V ELL + S+ + G+T LH+A Q ++++ L+ Sbjct: 220 CNNGVTPLHNAILYNRSAV--ELLINNRSINDTDVDGYTPLHYALQPPCSIDIIDILLYN 277 Query: 552 GVDIT 566 DI+ Sbjct: 278 NADIS 282
>ASZ1_PONPY (Q2IBE3) Ankyrin repeat, SAM and basic leucine zipper| domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein) Length = 475 Score = 46.2 bits (108), Expect = 6e-05 Identities = 34/122 (27%), Positives = 53/122 (43%), Gaps = 3/122 (2%) Frame = +3 Query: 204 AARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKC---LCKHKXXXXXX 374 AA +A V L D A +D+ S +A ++KC L Sbjct: 86 AASVANAELVRVLLDRGANASFEKDKQSILITACSARGSEEQILKCVELLLSRNADPNVA 145 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 I +A++ GH +VV L+A GA V ++ G+TAL +AA+ H +V L+ G Sbjct: 146 CRRLMTPIMYAARDGHTQVVALLVAHGAEVNTQDENGYTALTWAARQGHKNIVLKLLELG 205 Query: 555 VD 560 + Sbjct: 206 AN 207 Score = 42.0 bits (97), Expect = 0.001 Identities = 28/99 (28%), Positives = 43/99 (43%) Frame = +3 Query: 246 DSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHL 425 ++DP N R TP+ AA GH VV L H + +A+++GH Sbjct: 139 NADP---NVACRRLMTPIMYAARDGHTQVVALLVAHGAEVNTQDENGYTALTWAARQGHK 195 Query: 426 EVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYL 542 +V +LL GA+ + + G A +N H E+ L Sbjct: 196 NIVLKLLELGANKMLQTKDGKMPSEIAKRNKHHEIFNLL 234 Score = 37.7 bits (86), Expect = 0.023 Identities = 20/48 (41%), Positives = 32/48 (66%) Frame = +3 Query: 417 GHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVD 560 G + +V+ELL SG SV + + G+T L +AA ++ ELV+ L+ RG + Sbjct: 57 GDVSLVQELLDSGISVDSTFQYGWTPLMYAASVANAELVRVLLDRGAN 104
>ASZ1_OTOGA (Q2QLH1) Ankyrin repeat, SAM and basic leucine zipper| domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein) Length = 475 Score = 45.8 bits (107), Expect = 8e-05 Identities = 30/99 (30%), Positives = 45/99 (45%) Frame = +3 Query: 246 DSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHL 425 ++DP N R TP+ AA GH VV L H + +A+++GH Sbjct: 139 NADP---NVACRRLMTPIMYAARDGHPQVVALLVAHGAEVNTQDENGYTALTWAARQGHK 195 Query: 426 EVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYL 542 VV +LL GA+ + + G A +N HLE+ +L Sbjct: 196 NVVLKLLELGANKMLQTKDGKIPSEIAKRNKHLEIFNFL 234 Score = 44.7 bits (104), Expect = 2e-04 Identities = 41/157 (26%), Positives = 65/157 (41%), Gaps = 37/157 (23%) Frame = +3 Query: 201 KAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLC---------KH 353 KA +GD + V+ L DS ++++S R TPL AA +V++V+ L K Sbjct: 52 KALTTGDISLVQELLDSG-ISVDSSFRYGWTPLMYAASVANVELVRVLLDRGANASFDKD 110 Query: 354 KXXXXXXXXXXXXX----------------------------IHFASQKGHLEVVRELLA 449 K I +A++ GH +VV L+A Sbjct: 111 KQTILITACSARGLEEQILKCVELLLSRNADPNVACRRLMTPIMYAARDGHPQVVALLVA 170 Query: 450 SGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVD 560 GA V ++ G+TAL +AA+ H +V L+ G + Sbjct: 171 HGAEVNTQDENGYTALTWAARQGHKNVVLKLLELGAN 207
>ASB15_MOUSE (Q8VHS6) Ankyrin repeat and SOCS box protein 15 (ASB-15)| Length = 583 Score = 45.8 bits (107), Expect = 8e-05 Identities = 36/118 (30%), Positives = 54/118 (45%), Gaps = 1/118 (0%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 +H+AA+ G + L + ++ RD TPL +AA GH DV++ L HK Sbjct: 181 MHEAAKQGRKDIITLLLNHRG-NVHLRDGFGVTPLGVAAEYGHCDVLEHLI-HKGGDVFA 238 Query: 375 XXXXXXXIHF-ASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLV 545 + F A+ G+ + + LL G S NR G +H AA H +KYL+ Sbjct: 239 LADDGASVLFEAAGGGNPDCISLLLKYGGSGNVPNRAGHLPIHRAAYEGHYLALKYLI 296 Score = 35.4 bits (80), Expect = 0.11 Identities = 21/86 (24%), Positives = 37/86 (43%) Frame = +3 Query: 297 LHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKN 476 +H AA G D++ L H+ + A++ GH +V+ L+ G V A Sbjct: 181 MHEAAKQGRKDIITLLLNHRGNVHLRDGFGVTPLGVAAEYGHCDVLEHLIHKGGDVFALA 240 Query: 477 RKGFTALHFAAQNSHLELVKYLVRRG 554 G + L AA + + + L++ G Sbjct: 241 DDGASVLFEAAGGGNPDCISLLLKYG 266 Score = 34.7 bits (78), Expect = 0.20 Identities = 29/109 (26%), Positives = 45/109 (41%), Gaps = 11/109 (10%) Frame = +3 Query: 267 NSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELL 446 N +R P+H AA+ GH +K L IH A++ + + + L+ Sbjct: 270 NVPNRAGHLPIHRAAYEGHYLALKYLIP-VTSKHAIQKSGLTPIHSAAEGQNAQCLELLI 328 Query: 447 ASGASVKA-----------KNRKGFTALHFAAQNSHLELVKYLVRRGVD 560 +G VKA RK TAL+FA N+ + + L+ G D Sbjct: 329 ENGFDVKALLADHISQSYDDERK--TALYFAVSNNDIHCTEVLLAAGAD 375
>YL589_MIMIV (Q5UP49) Putative ankyrin repeat protein L589| Length = 274 Score = 45.8 bits (107), Expect = 8e-05 Identities = 22/53 (41%), Positives = 37/53 (69%) Frame = +3 Query: 405 ASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 A+Q GHLE+V+ + + A++ + N AL F++QN H+++VKYLV +G D+ Sbjct: 184 AAQFGHLELVKYSIDNRANIASYNNY---ALRFSSQNGHIDVVKYLVSKGADL 233
>KRIT1_MOUSE (Q6S5J6) Krev interaction trapped protein 1 (Krev interaction| trapped 1) (Cerebral cavernous malformations 1 protein homolog) Length = 736 Score = 45.8 bits (107), Expect = 8e-05 Identities = 29/88 (32%), Positives = 41/88 (46%), Gaps = 1/88 (1%) Frame = +3 Query: 186 DLKLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLC-KHKXX 362 D LH+ A GD+ + L D L++N D P+H A W G V+ + L K K Sbjct: 289 DFPLHRNACEGDSELLSHLLDKG-LSVNQLDNDHWAPIHYACWYGKVEATRILLEKGKCN 347 Query: 363 XXXXXXXXXXXIHFASQKGHLEVVRELL 446 +HFA+ GH E+V+ LL Sbjct: 348 PNLLNGQLSSPLHFAAGGGHAEIVQILL 375 Score = 29.6 bits (65), Expect = 6.3 Identities = 16/53 (30%), Positives = 23/53 (43%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKH 353 +H A G A L + N + +PLH AA GH ++V+ L H Sbjct: 325 IHYACWYGKVEATRILLEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILLTH 377
>ASZ1_CALMO (Q2QLB5) Ankyrin repeat, SAM and basic leucine zipper| domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein) Length = 476 Score = 45.8 bits (107), Expect = 8e-05 Identities = 33/122 (27%), Positives = 53/122 (43%), Gaps = 3/122 (2%) Frame = +3 Query: 204 AARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKC---LCKHKXXXXXX 374 AA +A V L D A +D+ + +A ++KC L Sbjct: 87 AASVANAELVRVLLDRGANASFEKDKQTILITACSAHGSEEQILKCVELLLSRNADPNVA 146 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 I +A++ GH +VV L+A GA V ++ G+TAL +AA+ H +V L+ G Sbjct: 147 CRRLMTPIMYAARDGHTQVVALLVAGGAEVNTQDENGYTALTWAARQGHKSIVLKLLELG 206 Query: 555 VD 560 + Sbjct: 207 AN 208 Score = 40.4 bits (93), Expect = 0.004 Identities = 22/48 (45%), Positives = 32/48 (66%) Frame = +3 Query: 417 GHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVD 560 G + +V+ELL SG SV A R G+T L +AA ++ ELV+ L+ RG + Sbjct: 58 GDVSLVQELLDSGISVDATFRYGWTPLMYAASVANAELVRVLLDRGAN 105 Score = 38.1 bits (87), Expect = 0.018 Identities = 27/99 (27%), Positives = 42/99 (42%) Frame = +3 Query: 246 DSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHL 425 ++DP N R TP+ AA GH VV L + +A+++GH Sbjct: 140 NADP---NVACRRLMTPIMYAARDGHTQVVALLVAGGAEVNTQDENGYTALTWAARQGHK 196 Query: 426 EVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYL 542 +V +LL GA+ + + G A +N H E+ L Sbjct: 197 SIVLKLLELGANKMLQTKDGKLPSEIAKRNKHHEIFNLL 235
>ASZ1_MICMU (Q2QL84) Ankyrin repeat, SAM and basic leucine zipper| domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein) Length = 481 Score = 45.8 bits (107), Expect = 8e-05 Identities = 30/99 (30%), Positives = 45/99 (45%) Frame = +3 Query: 246 DSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHL 425 ++DP N R TP+ AA GH VV L H + +A+++GH Sbjct: 139 NADP---NVACRRLMTPIMYAARDGHPQVVAVLVAHGAEVNTQDENGYTALTWAARQGHK 195 Query: 426 EVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYL 542 VV +LL GA+ + + G A +N HLE+ +L Sbjct: 196 NVVLKLLELGANKMLQTKDGKIPSEIAKRNKHLEIFNFL 234 Score = 45.1 bits (105), Expect = 1e-04 Identities = 41/157 (26%), Positives = 65/157 (41%), Gaps = 37/157 (23%) Frame = +3 Query: 201 KAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLC---------KH 353 KA +GD + V+ L DS ++++S R TPL AA +V++V+ L K Sbjct: 52 KALTTGDISLVQELLDSG-ISVDSSFRYGWTPLMYAASIANVELVRVLLDRGANASFDKD 110 Query: 354 KXXXXXXXXXXXXX----------------------------IHFASQKGHLEVVRELLA 449 K I +A++ GH +VV L+A Sbjct: 111 KQTILITACSARGSEEQILKCVELLLSRNADPNVACRRLMTPIMYAARDGHPQVVAVLVA 170 Query: 450 SGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVD 560 GA V ++ G+TAL +AA+ H +V L+ G + Sbjct: 171 HGAEVNTQDENGYTALTWAARQGHKNVVLKLLELGAN 207
>ACBD6_RAT (Q5RJK8) Acyl-CoA-binding domain-containing protein 6| Length = 282 Score = 45.8 bits (107), Expect = 8e-05 Identities = 21/57 (36%), Positives = 36/57 (63%) Frame = +3 Query: 396 IHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDIT 566 +H+A +GH E+V+ LL A + ++ +G TALH+AA ++V+ L++ G D T Sbjct: 196 LHWACDRGHKELVKVLLQCEAGINCQDNEGQTALHYAAACEFSDIVELLLQSGADPT 252 Score = 34.3 bits (77), Expect = 0.26 Identities = 23/100 (23%), Positives = 40/100 (40%) Frame = +3 Query: 186 DLKLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXX 365 D + R + + S + +N D R LH A GH ++VK L + + Sbjct: 159 DKNIFDYCRENNIDHITKAIKSKTVDVNMTDEEGRALLHWACDRGHKELVKVLLQCEAGI 218 Query: 366 XXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKG 485 +H+A+ ++V LL SGA +++ G Sbjct: 219 NCQDNEGQTALHYAAACEFSDIVELLLQSGADPTLRDQDG 258
>ACBD6_HUMAN (Q9BR61) Acyl-CoA-binding domain-containing protein 6| Length = 282 Score = 45.8 bits (107), Expect = 8e-05 Identities = 21/57 (36%), Positives = 36/57 (63%) Frame = +3 Query: 396 IHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDIT 566 +H+A +GH E+V LL A + ++ +G TALH+A+ L++V+ L++ G D T Sbjct: 196 LHWACDRGHKELVTVLLQHRADINCQDNEGQTALHYASACEFLDIVELLLQSGADPT 252 Score = 40.4 bits (93), Expect = 0.004 Identities = 25/100 (25%), Positives = 42/100 (42%) Frame = +3 Query: 186 DLKLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXX 365 D + R + + S + +N +D R LH A GH ++V L +H+ Sbjct: 159 DKNIFDYCRENNIDHITKAIKSKNVDVNVKDEEGRALLHWACDRGHKELVTVLLQHRADI 218 Query: 366 XXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKG 485 +H+AS L++V LL SGA +++ G Sbjct: 219 NCQDNEGQTALHYASACEFLDIVELLLQSGADPTLRDQDG 258 Score = 30.0 bits (66), Expect = 4.8 Identities = 13/45 (28%), Positives = 22/45 (48%) Frame = +3 Query: 429 VVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 + + + + V K+ +G LH+A H ELV L++ DI Sbjct: 174 ITKAIKSKNVDVNVKDEEGRALLHWACDRGHKELVTVLLQHRADI 218
>ASB4_MOUSE (Q9WV71) Ankyrin repeat and SOCS box protein 4 (ASB-4)| Length = 426 Score = 45.8 bits (107), Expect = 8e-05 Identities = 34/122 (27%), Positives = 52/122 (42%), Gaps = 2/122 (1%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH + G + L D + +N R +TPLH+A +++ VK LC Sbjct: 79 LHLSVLLGHVECLMVLLDHNA-TINCRPN-GKTPLHVACEIANLECVKILCDRGAKLNCY 136 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASV--KAKNRKGFTALHFAAQNSHLELVKYLVR 548 +HF + + ++L+ GA+V K N+ T LH AA ELV + V Sbjct: 137 SLSGHTALHFCTTPSSILCAKQLVLRGANVNMKTNNQDEETPLHTAAHFGLSELVAFYVE 196 Query: 549 RG 554 G Sbjct: 197 NG 198 Score = 45.8 bits (107), Expect = 8e-05 Identities = 29/91 (31%), Positives = 41/91 (45%) Frame = +3 Query: 291 TPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKA 470 T LHL+ GHV+ + L H +H A + +LE V+ L GA + Sbjct: 77 TGLHLSVLLGHVECLMVLLDHNATINCRPNGKTP-LHVACEIANLECVKILCDRGAKLNC 135 Query: 471 KNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 + G TALHF S + K LV RG ++ Sbjct: 136 YSLSGHTALHFCTTPSSILCAKQLVLRGANV 166
>UACA_BOVIN (Q8HYY4) Uveal autoantigen with coiled-coil domains and ankyrin| repeats protein (Beta-actin-binding protein) (BetaCAP73) Length = 1401 Score = 45.4 bits (106), Expect = 1e-04 Identities = 31/124 (25%), Positives = 54/124 (43%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AA+ G A ++ L + D RT LH AA A ++ LC H Sbjct: 92 LHLAAKYGHALCLQKLLQYN-CPTEHVDLQGRTALHDAAMADCPSSIQLLCDHGASVNAK 150 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 + A+Q + + L+ GA + +++++ TAL + + V+ L++ G Sbjct: 151 DVDGRTPLVLATQMCRPTICQLLIDRGADINSRDKQNRTALMLGCEYGCKDAVEVLIKNG 210 Query: 555 VDIT 566 D+T Sbjct: 211 ADVT 214 Score = 44.3 bits (103), Expect = 2e-04 Identities = 29/126 (23%), Positives = 52/126 (41%) Frame = +3 Query: 186 DLKLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXX 365 D +L +AA GD V S+ + D R+ H+ A G+++ + + H Sbjct: 22 DDRLMRAAERGDVEKVSSILAKKGVNPGKLDVEGRSAFHVVASKGNLECLNAILIHGVDI 81 Query: 366 XXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLV 545 +H A++ GH +++LL + + +G TALH AA ++ L Sbjct: 82 TTSDTAGRNALHLAAKYGHALCLQKLLQYNCPTEHVDLQGRTALHDAAMADCPSSIQLLC 141 Query: 546 RRGVDI 563 G + Sbjct: 142 DHGASV 147 Score = 41.6 bits (96), Expect = 0.002 Identities = 29/102 (28%), Positives = 44/102 (43%) Frame = +3 Query: 264 LNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVREL 443 + + D R LHLAA GH ++ L ++ +H A+ ++ L Sbjct: 81 ITTSDTAGRNALHLAAKYGHALCLQKLLQYNCPTEHVDLQGRTALHDAAMADCPSSIQLL 140 Query: 444 LASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDITT 569 GASV AK+ G T L A Q + + L+ RG DI + Sbjct: 141 CDHGASVNAKDVDGRTPLVLATQMCRPTICQLLIDRGADINS 182 Score = 33.5 bits (75), Expect = 0.44 Identities = 19/56 (33%), Positives = 32/56 (57%), Gaps = 1/56 (1%) Frame = +3 Query: 405 ASQKGHLEVVRELLAS-GASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDITT 569 A+++G +E V +LA G + + +G +A H A +LE + ++ GVDITT Sbjct: 28 AAERGDVEKVSSILAKKGVNPGKLDVEGRSAFHVVASKGNLECLNAILIHGVDITT 83
>AKT1_ORYSA (Q8VYX2) Potassium channel AKT1 (OsAKT1)| Length = 935 Score = 45.4 bits (106), Expect = 1e-04 Identities = 35/125 (28%), Positives = 56/125 (44%), Gaps = 2/125 (1%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCD--SDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXX 368 LH AA G+ V L + +DP N+RD + PL A H VV+ L + Sbjct: 603 LHIAASKGNEQCVRLLLEYGADP---NARDSEGKVPLWEALCEKHAAVVQLLVEGGADLS 659 Query: 369 XXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVR 548 I A ++ E++ +++ G V R G TALH A + ++++ + L+ Sbjct: 660 SGDTGLYACI--AVEESDTELLNDIIHYGGDVNRARRDGTTALHRAVCDGNVQMAELLLE 717 Query: 549 RGVDI 563 G DI Sbjct: 718 HGADI 722 Score = 37.4 bits (85), Expect = 0.030 Identities = 20/58 (34%), Positives = 32/58 (55%) Frame = +3 Query: 396 IHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDITT 569 +H A+ KG+ + VR LL GA A++ +G L A H +V+ LV G D+++ Sbjct: 603 LHIAASKGNEQCVRLLLEYGADPNARDSEGKVPLWEALCEKHAAVVQLLVEGGADLSS 660 Score = 32.3 bits (72), Expect = 0.97 Identities = 17/53 (32%), Positives = 26/53 (49%) Frame = +3 Query: 402 FASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVD 560 FA +G ++ +LL G + G TALH AA + + V+ L+ G D Sbjct: 572 FAVTRGDDFLLHQLLKRGMDPNESDNDGHTALHIAASKGNEQCVRLLLEYGAD 624
>IKBA_PIG (Q08353) NF-kappa-B inhibitor alpha (I-kappa-B-alpha)| (IkappaBalpha) (IKB-alpha) (ECI-6) Length = 314 Score = 45.4 bits (106), Expect = 1e-04 Identities = 40/132 (30%), Positives = 58/132 (43%), Gaps = 9/132 (6%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDS--DPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXX 368 LH A + E+L ++ DP RD TPLHLA G + V L + + Sbjct: 115 LHLAVITNQPEIAEALLEAGCDP---ELRDFRGNTPLHLACEQGCLASVGVLTQPRGTQH 171 Query: 369 XXXXXXXXX------IHFASQKGHLEVVRELLASGASVKAKNR-KGFTALHFAAQNSHLE 527 +H AS G+L +V L++ GA V A+ G TALH A + + Sbjct: 172 LHSILQATNYNGHTCLHLASIHGYLGIVELLVSLGADVNAQEPCNGRTALHLAVDLQNPD 231 Query: 528 LVKYLVRRGVDI 563 LV L++ G D+ Sbjct: 232 LVSLLLKCGADV 243 Score = 43.1 bits (100), Expect = 5e-04 Identities = 29/106 (27%), Positives = 48/106 (45%), Gaps = 6/106 (5%) Frame = +3 Query: 264 LNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVREL 443 LN ++ L +TPLHLA ++ + L + +H A ++G L V L Sbjct: 104 LNFQNNLQQTPLHLAVITNQPEIAEALLEAGCDPELRDFRGNTPLHLACEQGCLASVGVL 163 Query: 444 LASGAS------VKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 + ++A N G T LH A+ + +L +V+ LV G D+ Sbjct: 164 TQPRGTQHLHSILQATNYNGHTCLHLASIHGYLGIVELLVSLGADV 209
>IKBA_MOUSE (Q9Z1E3) NF-kappa-B inhibitor alpha (I-kappa-B-alpha)| (IkappaBalpha) (IKB-alpha) Length = 314 Score = 45.4 bits (106), Expect = 1e-04 Identities = 41/132 (31%), Positives = 56/132 (42%), Gaps = 9/132 (6%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDS--DPLALNSRDRLSRTPLHLAAWAGHVDVVK-----CLCKH 353 LH A + E+L + DP RD TPLHLA G + V C +H Sbjct: 115 LHLAVITNQPGIAEALLKAGCDP---ELRDFRGNTPLHLACEQGCLASVAVLTQTCTPQH 171 Query: 354 KXXXXXXXXXXXXX-IHFASQKGHLEVVRELLASGASVKAKNR-KGFTALHFAAQNSHLE 527 +H AS G+L +V L+ GA V A+ G TALH A + + Sbjct: 172 LHSVLQATNYNGHTCLHLASIHGYLAIVEHLVTLGADVNAQEPCNGRTALHLAVDLQNPD 231 Query: 528 LVKYLVRRGVDI 563 LV L++ G D+ Sbjct: 232 LVSLLLKCGADV 243 Score = 45.4 bits (106), Expect = 1e-04 Identities = 30/106 (28%), Positives = 49/106 (46%), Gaps = 6/106 (5%) Frame = +3 Query: 264 LNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVREL 443 LN ++ L +TPLHLA + + L K +H A ++G L V L Sbjct: 104 LNFQNNLQQTPLHLAVITNQPGIAEALLKAGCDPELRDFRGNTPLHLACEQGCLASVAVL 163 Query: 444 LAS------GASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 + + ++A N G T LH A+ + +L +V++LV G D+ Sbjct: 164 TQTCTPQHLHSVLQATNYNGHTCLHLASIHGYLAIVEHLVTLGADV 209
>AKR1_SACKL (Q875S9) Palmitoyltransferase AKR1 (EC 2.3.1.-) (Ankyrin| repeat-containing protein AKR1) Length = 737 Score = 45.4 bits (106), Expect = 1e-04 Identities = 33/121 (27%), Positives = 59/121 (48%), Gaps = 3/121 (2%) Frame = +3 Query: 192 KLHKAARSGDAAAVESLCDSDPLAL-NSRDRLSRTP-LHLAAWAGHVDVVKCLC-KHKXX 362 K H A + GD A V+ + ++ + L + D + R LH A+ + VV+ L K Sbjct: 58 KYHLACQQGDLATVKEIIENGVIDLKHDYDDVERVSGLHWASINNRLSVVRYLISKDVDV 117 Query: 363 XXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYL 542 +H+A++ G++ +V LL GA + +GF LH + +S++ LV Y+ Sbjct: 118 NFQGGELNATPLHWAARYGYVYIVDYLLEHGADPSVTDAQGFNLLHLSINSSNIMLVIYV 177 Query: 543 V 545 + Sbjct: 178 L 178 Score = 42.0 bits (97), Expect = 0.001 Identities = 38/159 (23%), Positives = 57/159 (35%), Gaps = 37/159 (23%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH A+ + + V L D L+ TPLH AA G+V +V L +H Sbjct: 95 LHWASINNRLSVVRYLISKDVDVNFQGGELNATPLHWAARYGYVYIVDYLLEHGADPSVT 154 Query: 375 XXXXXXXIH-------------------------------------FASQKGHLEVVREL 443 +H +A+ +G V L Sbjct: 155 DAQGFNLLHLSINSSNIMLVIYVLFFVIDDKLDIDCVDPNGRTALLWAAYQGDSLSVETL 214 Query: 444 LASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVD 560 L ASVKA ++ GFT LH+ +++K+L+ G D Sbjct: 215 LKFRASVKATDKGGFTPLHWGTVKGQAQVLKHLIENGAD 253 Score = 36.6 bits (83), Expect = 0.051 Identities = 19/59 (32%), Positives = 36/59 (61%), Gaps = 4/59 (6%) Frame = +3 Query: 399 HFASQKGHLEVVRELLASGASVKAKNR----KGFTALHFAAQNSHLELVKYLVRRGVDI 563 H A Q+G L V+E++ +G + K+ + + LH+A+ N+ L +V+YL+ + VD+ Sbjct: 60 HLACQQGDLATVKEIIENGV-IDLKHDYDDVERVSGLHWASINNRLSVVRYLISKDVDV 117
>ZDH13_PONPY (Q5NVB9) Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc| finger DHHC domain-containing protein 13) (DHHC-13) Length = 622 Score = 45.4 bits (106), Expect = 1e-04 Identities = 27/97 (27%), Positives = 49/97 (50%), Gaps = 1/97 (1%) Frame = +3 Query: 276 DRLSRTPLHLAAWAGHVDVVKC-LCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLAS 452 D+ + + LH AA +D+VK + K +H+A ++GHL +V LL Sbjct: 79 DKENVSLLHWAAINNRLDLVKFYISKGAVVDQLGGDLNSTPLHWAIRQGHLPMVILLLQH 138 Query: 453 GASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 GA + +GF+++H A H+ ++ YL+ +G + Sbjct: 139 GADPTLIDGEGFSSIHLAVLFQHMPIIAYLISKGQSV 175 Score = 39.7 bits (91), Expect = 0.006 Identities = 18/50 (36%), Positives = 33/50 (66%) Frame = +3 Query: 405 ASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 A+Q G E +EL+ +G V+ +++ + LH+AA N+ L+LVK+ + +G Sbjct: 56 ATQYGIFERCKELVEAGYDVRQPDKENVSLLHWAAINNRLDLVKFYISKG 105 Score = 38.9 bits (89), Expect = 0.010 Identities = 23/76 (30%), Positives = 34/76 (44%) Frame = +3 Query: 282 LSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGAS 461 L+ TPLH A GH+ +V L +H IH A H+ ++ L++ G S Sbjct: 115 LNSTPLHWAIRQGHLPMVILLLQHGADPTLIDGEGFSSIHLAVLFQHMPIIAYLISKGQS 174 Query: 462 VKAKNRKGFTALHFAA 509 V + G T L +A Sbjct: 175 VNMTDVNGQTPLMLSA 190 Score = 32.0 bits (71), Expect = 1.3 Identities = 18/58 (31%), Positives = 32/58 (55%), Gaps = 1/58 (1%) Frame = +3 Query: 396 IHFASQKGHLEVVRELLASGASV-KAKNRKGFTALHFAAQNSHLELVKYLVRRGVDIT 566 +H+A+ L++V+ ++ GA V + T LH+A + HL +V L++ G D T Sbjct: 86 LHWAAINNRLDLVKFYISKGAVVDQLGGDLNSTPLHWAIRQGHLPMVILLLQHGADPT 143
>RN5A_HUMAN (Q05823) 2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent| RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4) Length = 741 Score = 45.4 bits (106), Expect = 1e-04 Identities = 31/123 (25%), Positives = 54/123 (43%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 L KA ++ D V+ L + + TPLH A D+V+ L +H Sbjct: 29 LIKAVQNEDVDLVQQLLEGGANVNFQEEEGGWTPLHNAVQMSREDIVELLLRHGADPVLR 88 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 A+ G +++++ L+ GA V + GFTA AA ++ +K+L +RG Sbjct: 89 KKNGATPFILAAIAGSVKLLKLFLSKGADVNECDFYGFTAFMEAAVYGKVKALKFLYKRG 148 Query: 555 VDI 563 ++ Sbjct: 149 ANV 151 Score = 34.7 bits (78), Expect = 0.20 Identities = 36/136 (26%), Positives = 56/136 (41%), Gaps = 13/136 (9%) Frame = +3 Query: 195 LHKAARSGDAAAVESLC--DSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXX 368 LH A + VE L +DP+ R + TP LAA AG V ++K Sbjct: 63 LHNAVQMSREDIVELLLRHGADPVL---RKKNGATPFILAAIAGSVKLLKLFLSKGADVN 119 Query: 369 XXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRK----------GFTALHFAAQNS 518 A+ G ++ ++ L GA+V + + G TAL AA+ Sbjct: 120 ECDFYGFTAFMEAAVYGKVKALKFLYKRGANVNLRRKTKEDQERLRKGGATALMDAAEKG 179 Query: 519 HLELVKYLV-RRGVDI 563 H+E++K L+ G D+ Sbjct: 180 HVEVLKILLDEMGADV 195
>ASB3_MOUSE (Q9WV72) Ankyrin repeat and SOCS box protein 3 (ASB-3)| Length = 525 Score = 45.4 bits (106), Expect = 1e-04 Identities = 33/122 (27%), Positives = 50/122 (40%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 L A SG ++ L S LH A++ G+ + +K L K Sbjct: 116 LFLAVESGRIDVLKLLLQHGANVNGSHSMSGWNSLHQASFQGNAETIKLLLKQGADRECQ 175 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 + A+Q G LE + L++SGA+V + T L AAQ H + V+ L+ G Sbjct: 176 DDFGITPLFVAAQYGKLESMSILISSGANVNCQALDKATPLFIAAQEGHTKCVELLLSSG 235 Query: 555 VD 560 D Sbjct: 236 AD 237 Score = 43.1 bits (100), Expect = 5e-04 Identities = 30/127 (23%), Positives = 58/127 (45%), Gaps = 3/127 (2%) Frame = +3 Query: 189 LKLHKAARSGDAAAVESLC--DSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXX 362 + +H+AA ++ L DS + ++ LHLA GH + + L + Sbjct: 45 MPIHEAAYHNAVECLQMLIHTDSSENYIKAKTFEGFCALHLAVSQGHWKITQILLEAGAD 104 Query: 363 XXXXXXXXXXXIHFASQKGHLEVVRELLASGASVK-AKNRKGFTALHFAAQNSHLELVKY 539 + A + G ++V++ LL GA+V + + G+ +LH A+ + E +K Sbjct: 105 PNETTLEETTPLFLAVESGRIDVLKLLLQHGANVNGSHSMSGWNSLHQASFQGNAETIKL 164 Query: 540 LVRRGVD 560 L+++G D Sbjct: 165 LLKQGAD 171 Score = 37.7 bits (86), Expect = 0.023 Identities = 26/123 (21%), Positives = 54/123 (43%), Gaps = 3/123 (2%) Frame = +3 Query: 204 AARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLC---KHKXXXXXX 374 AAR G+ + L +++ D P+H AA+ V+ ++ L + Sbjct: 17 AAREGNVKILRKLLKKGR-SVDVADNRGWMPIHEAAYHNAVECLQMLIHTDSSENYIKAK 75 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 +H A +GH ++ + LL +GA + T L A ++ ++++K L++ G Sbjct: 76 TFEGFCALHLAVSQGHWKITQILLEAGADPNETTLEETTPLFLAVESGRIDVLKLLLQHG 135 Query: 555 VDI 563 ++ Sbjct: 136 ANV 138
>V162_FOWPV (Q9J569) Putative ankyrin repeat protein FPV162| Length = 603 Score = 45.4 bits (106), Expect = 1e-04 Identities = 40/135 (29%), Positives = 61/135 (45%), Gaps = 7/135 (5%) Frame = +3 Query: 186 DLKLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGH-VDVVKCLCKHKXX 362 D LH AARS + + +N+ + +S TPLHLA ++ + + +K L +H Sbjct: 263 DTPLHCAARSRNPVHKLKTLIAHGSNVNAVNGISVTPLHLATYSDNATEALKVLIEHGAE 322 Query: 363 XXXXXXXXXXXIHFASQ---KGHLEVVRELLAS-GASVKAKNRKGFTALHFAAQNSH--L 524 +H+ S+ L+ ELL GA ++AKN G T L A N L Sbjct: 323 VNSVDIYGRTPMHYISRSYSSQSLKTAVELLVEHGADIEAKNVIGGTPLSSACNNIEYDL 382 Query: 525 ELVKYLVRRGVDITT 569 L++ + G DI T Sbjct: 383 RLIECFIEYGADINT 397 Score = 35.0 bits (79), Expect = 0.15 Identities = 26/95 (27%), Positives = 41/95 (43%), Gaps = 2/95 (2%) Frame = +3 Query: 291 TPLHLAAWAGH-VDVVKCLCKHKXXXXXXXXXXXXXIHFASQK-GHLEVVRELLASGASV 464 TPLH A V+ ++ +H+A++K EV++ L+ G +V Sbjct: 26 TPLHKAVMLPDAVERIRMFVSKGADINVISDFKKTALHYAAKKLATPEVLKTLIYLGTNV 85 Query: 465 KAKNRKGFTALHFAAQNSHLELVKYLVRRGVDITT 569 + T LH+A Q + LE K L+ G D T Sbjct: 86 NVTDMFESTPLHYAVQENGLEATKKLLDLGADPNT 120
>AKR2_YEAST (Q12013) Probable palmitoyltransferase AKR2 (EC 2.3.1.-) (Ankyrin| repeat-containing protein AKR2) Length = 749 Score = 45.4 bits (106), Expect = 1e-04 Identities = 31/117 (26%), Positives = 58/117 (49%), Gaps = 2/117 (1%) Frame = +3 Query: 201 KAARSGDAAAVESLCDSDPLALNSRDRLSR-TPLHLAAWAGHVDVVK-CLCKHKXXXXXX 374 +AA+ GD V+ + +S + +N+ DR+ + LH A V K L + Sbjct: 56 EAAKDGDLKVVKDVVESGAVDINN-DRIDELSGLHWACINNRFSVAKFLLLRGANPNQAA 114 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLV 545 +H+A++ G++ +V LL GA K+ +G +HF+ +S++ LV Y++ Sbjct: 115 GPGGATALHWAARYGNIYIVDLLLKHGADPTLKDEQGLNIMHFSVYSSNILLVVYVL 171 Score = 36.6 bits (83), Expect = 0.051 Identities = 22/79 (27%), Positives = 38/79 (48%) Frame = +3 Query: 246 DSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHL 425 ++D + ++S+D +RTPL AA+ G V+ L K +H A G Sbjct: 177 NNDNVDIDSKDNNNRTPLLWAAYQGDFLTVELLLKFGSTVAWTDNRGFNALHCALVGGDQ 236 Query: 426 EVVRELLASGASVKAKNRK 482 V+ +L+ SGA+ +N + Sbjct: 237 RVICDLILSGANFYERNNQ 255 Score = 33.9 bits (76), Expect = 0.33 Identities = 20/58 (34%), Positives = 32/58 (55%), Gaps = 1/58 (1%) Frame = +3 Query: 396 IHFASQKGHLEVVRELLASGASV-KAKNRKGFTALHFAAQNSHLELVKYLVRRGVDIT 566 +H+A V + LL GA+ +A G TALH+AA+ ++ +V L++ G D T Sbjct: 88 LHWACINNRFSVAKFLLLRGANPNQAAGPGGATALHWAARYGNIYIVDLLLKHGADPT 145 Score = 31.6 bits (70), Expect = 1.7 Identities = 16/53 (30%), Positives = 31/53 (58%), Gaps = 1/53 (1%) Frame = +3 Query: 405 ASQKGHLEVVRELLASGA-SVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVD 560 A++ G L+VV++++ SGA + + LH+A N+ + K+L+ RG + Sbjct: 57 AAKDGDLKVVKDVVESGAVDINNDRIDELSGLHWACINNRFSVAKFLLLRGAN 109
>ASZ1_PAPAN (Q8WMX7) Ankyrin repeat, SAM and basic leucine zipper| domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein) Length = 475 Score = 45.4 bits (106), Expect = 1e-04 Identities = 33/122 (27%), Positives = 53/122 (43%), Gaps = 3/122 (2%) Frame = +3 Query: 204 AARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKC---LCKHKXXXXXX 374 AA +A V L D A +D+ + +A ++KC L Sbjct: 86 AASVANAELVRVLLDRGANASFEKDKQTILITACSAHGSEEQILKCVELLLSRNADPNVA 145 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 I +A++ GH +VV L+A GA V ++ G+TAL +AA+ H +V L+ G Sbjct: 146 CRRLMTPIMYAARDGHTQVVALLVAHGAEVNTQDENGYTALTWAARQGHKNIVLKLLELG 205 Query: 555 VD 560 + Sbjct: 206 AN 207 Score = 42.0 bits (97), Expect = 0.001 Identities = 28/99 (28%), Positives = 43/99 (43%) Frame = +3 Query: 246 DSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHL 425 ++DP N R TP+ AA GH VV L H + +A+++GH Sbjct: 139 NADP---NVACRRLMTPIMYAARDGHTQVVALLVAHGAEVNTQDENGYTALTWAARQGHK 195 Query: 426 EVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYL 542 +V +LL GA+ + + G A +N H E+ L Sbjct: 196 NIVLKLLELGANKMLQTKDGKMPSEIAKRNKHHEIFNLL 234 Score = 37.7 bits (86), Expect = 0.023 Identities = 20/48 (41%), Positives = 32/48 (66%) Frame = +3 Query: 417 GHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVD 560 G + +V+ELL SG SV + + G+T L +AA ++ ELV+ L+ RG + Sbjct: 57 GDVSLVQELLDSGISVDSTFQYGWTPLMYAASVANAELVRVLLDRGAN 104
>IKBA_RAT (Q63746) NF-kappa-B inhibitor alpha (I-kappa-B-alpha)| (IkappaBalpha) (IKB-alpha) (RL/IF-1) Length = 314 Score = 45.1 bits (105), Expect = 1e-04 Identities = 41/132 (31%), Positives = 56/132 (42%), Gaps = 9/132 (6%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDS--DPLALNSRDRLSRTPLHLAAWAGHVDVVK-----CLCKH 353 LH A + E+L + DP RD TPLHLA G + V C +H Sbjct: 115 LHLAVITNQPGIAEALLKAGCDP---ELRDFRGNTPLHLACEQGCLASVAVLTQTCTPQH 171 Query: 354 KXXXXXXXXXXXXX-IHFASQKGHLEVVRELLASGASVKAKNR-KGFTALHFAAQNSHLE 527 +H AS G+L +V L+ GA V A+ G TALH A + + Sbjct: 172 LHSVLQATNYNGHTCLHLASIHGYLGIVEHLVTLGADVNAQEPCNGRTALHLAVDLQNPD 231 Query: 528 LVKYLVRRGVDI 563 LV L++ G D+ Sbjct: 232 LVSLLLKCGADV 243 Score = 45.1 bits (105), Expect = 1e-04 Identities = 30/106 (28%), Positives = 49/106 (46%), Gaps = 6/106 (5%) Frame = +3 Query: 264 LNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVREL 443 LN ++ L +TPLHLA + + L K +H A ++G L V L Sbjct: 104 LNFQNNLQQTPLHLAVITNQPGIAEALLKAGCDPELRDFRGNTPLHLACEQGCLASVAVL 163 Query: 444 LAS------GASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 + + ++A N G T LH A+ + +L +V++LV G D+ Sbjct: 164 TQTCTPQHLHSVLQATNYNGHTCLHLASIHGYLGIVEHLVTLGADV 209
>ZDH13_MOUSE (Q9CWU2) Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc| finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein) Length = 622 Score = 45.1 bits (105), Expect = 1e-04 Identities = 27/97 (27%), Positives = 49/97 (50%), Gaps = 1/97 (1%) Frame = +3 Query: 276 DRLSRTPLHLAAWAGHVDVVKC-LCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLAS 452 DR + + LH AA +++VK + K +H+A ++GHL +V LL Sbjct: 79 DRENVSLLHWAAINNRLELVKFYISKGAVIDQLGGDLNSTPLHWAIRQGHLPMVILLLQH 138 Query: 453 GASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 GA + +GF+++H A H+ ++ YL+ +G + Sbjct: 139 GADPTLIDGEGFSSIHLAVLFQHMPIIAYLISKGQSV 175 Score = 42.4 bits (98), Expect = 0.001 Identities = 21/53 (39%), Positives = 34/53 (64%) Frame = +3 Query: 405 ASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 A+Q G E +EL+ +G V+ +R+ + LH+AA N+ LELVK+ + +G I Sbjct: 56 ATQYGIFERCKELVEAGYDVRQPDRENVSLLHWAAINNRLELVKFYISKGAVI 108 Score = 38.9 bits (89), Expect = 0.010 Identities = 23/76 (30%), Positives = 34/76 (44%) Frame = +3 Query: 282 LSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGAS 461 L+ TPLH A GH+ +V L +H IH A H+ ++ L++ G S Sbjct: 115 LNSTPLHWAIRQGHLPMVILLLQHGADPTLIDGEGFSSIHLAVLFQHMPIIAYLISKGQS 174 Query: 462 VKAKNRKGFTALHFAA 509 V + G T L +A Sbjct: 175 VNMTDVNGQTPLMLSA 190 Score = 32.7 bits (73), Expect = 0.74 Identities = 18/58 (31%), Positives = 32/58 (55%), Gaps = 1/58 (1%) Frame = +3 Query: 396 IHFASQKGHLEVVRELLASGASV-KAKNRKGFTALHFAAQNSHLELVKYLVRRGVDIT 566 +H+A+ LE+V+ ++ GA + + T LH+A + HL +V L++ G D T Sbjct: 86 LHWAAINNRLELVKFYISKGAVIDQLGGDLNSTPLHWAIRQGHLPMVILLLQHGADPT 143
>IKBA_HUMAN (P25963) NF-kappa-B inhibitor alpha (Major histocompatibility| complex enhancer-binding protein MAD3) (I-kappa-B-alpha) (IkappaBalpha) (IKB-alpha) Length = 317 Score = 45.1 bits (105), Expect = 1e-04 Identities = 31/106 (29%), Positives = 48/106 (45%), Gaps = 6/106 (5%) Frame = +3 Query: 264 LNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVREL 443 LN ++ L +TPLHLA ++ + L +H A ++G L V L Sbjct: 104 LNFQNNLQQTPLHLAVITNQPEIAEALLGAGCDPELRDFRGNTPLHLACEQGCLASVGVL 163 Query: 444 LASGAS------VKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 S + +KA N G T LH A+ + +L +V+ LV G D+ Sbjct: 164 TQSCTTPHLHSILKATNYNGHTCLHLASIHGYLGIVELLVSLGADV 209 Score = 44.3 bits (103), Expect = 2e-04 Identities = 41/132 (31%), Positives = 56/132 (42%), Gaps = 9/132 (6%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDS--DPLALNSRDRLSRTPLHLAAWAGHVDVV-----KCLCKH 353 LH A + E+L + DP RD TPLHLA G + V C H Sbjct: 115 LHLAVITNQPEIAEALLGAGCDP---ELRDFRGNTPLHLACEQGCLASVGVLTQSCTTPH 171 Query: 354 KXXXXXXXXXXXXX-IHFASQKGHLEVVRELLASGASVKAKNR-KGFTALHFAAQNSHLE 527 +H AS G+L +V L++ GA V A+ G TALH A + + Sbjct: 172 LHSILKATNYNGHTCLHLASIHGYLGIVELLVSLGADVNAQEPCNGRTALHLAVDLQNPD 231 Query: 528 LVKYLVRRGVDI 563 LV L++ G D+ Sbjct: 232 LVSLLLKCGADV 243
>ASZ1_CARPS (Q2QLC6) Ankyrin repeat, SAM and basic leucine zipper| domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein) Length = 475 Score = 45.1 bits (105), Expect = 1e-04 Identities = 41/157 (26%), Positives = 65/157 (41%), Gaps = 37/157 (23%) Frame = +3 Query: 201 KAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLC---------KH 353 KA +GD + V+ L +S ++++S R TPL AA +V++V+ L K Sbjct: 52 KALTTGDISLVQELLNSG-ISVDSSFRYGWTPLMYAASVSNVELVRVLLDRGANANFDKD 110 Query: 354 KXXXXXXXXXXXXX----------------------------IHFASQKGHLEVVRELLA 449 K I +A++ GH +VV L+A Sbjct: 111 KQTILITTCSSRGSEEQIVKCVELLLSRNADPNVPCRRLMTPIMYAARDGHPQVVALLVA 170 Query: 450 SGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVD 560 GA V ++ G+TAL +AA+ H +V L+ G D Sbjct: 171 HGAEVNTQDESGYTALTWAARQGHKNVVLKLLELGAD 207 Score = 40.8 bits (94), Expect = 0.003 Identities = 25/84 (29%), Positives = 36/84 (42%) Frame = +3 Query: 291 TPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKA 470 TP+ AA GH VV L H + +A+++GH VV +LL GA Sbjct: 151 TPIMYAARDGHPQVVALLVAHGAEVNTQDESGYTALTWAARQGHKNVVLKLLELGADKML 210 Query: 471 KNRKGFTALHFAAQNSHLELVKYL 542 + + G A + HLE+ L Sbjct: 211 QTKDGNIPSEIAKRYKHLEIFSLL 234
>AKR1_SACCA (Q876A6) Palmitoyltransferase AKR1 (EC 2.3.1.-) (Ankyrin| repeat-containing protein AKR1) (Fragments) Length = 742 Score = 45.1 bits (105), Expect = 1e-04 Identities = 24/56 (42%), Positives = 35/56 (62%), Gaps = 1/56 (1%) Frame = +3 Query: 399 HFASQKGHLEVVRELLASGASVKAKNRKG-FTALHFAAQNSHLELVKYLVRRGVDI 563 H A QKG L V++LL SG + G T LH+A+ N+ L +VKYL+ +G+D+ Sbjct: 64 HQACQKGDLATVKQLLDSGVLDLNTDLTGDITGLHWASINNRLSVVKYLISQGIDV 119 Score = 40.4 bits (93), Expect = 0.004 Identities = 46/178 (25%), Positives = 63/178 (35%), Gaps = 57/178 (32%) Frame = +3 Query: 198 HKAARSGDAAAVESLCDSDPLALNS--------------RDRLS---------------- 287 H+A + GD A V+ L DS L LN+ +RLS Sbjct: 64 HQACQKGDLATVKQLLDSGVLDLNTDLTGDITGLHWASINNRLSVVKYLISQGIDVNAKA 123 Query: 288 ----RTPLHLAAWAGHVDVVKCLC-----------------------KHKXXXXXXXXXX 386 TPLH AA G+V +V CL K Sbjct: 124 GDLEATPLHWAARYGYVHIVDCLLNKGADPTMCEVHVVEFLLPVLFFKGIIDIDCQDPKG 183 Query: 387 XXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVD 560 + +A+ +G V LL GAS K + GFT LH+A ++ +L+R G D Sbjct: 184 RTPLLWAAYQGDSLSVMLLLKFGASTKIVDEGGFTPLHWATVKGQPYVLTHLIRDGAD 241 Score = 30.8 bits (68), Expect = 2.8 Identities = 21/74 (28%), Positives = 30/74 (40%) Frame = +3 Query: 264 LNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVREL 443 ++ +D RTPL AA+ G V L K +H+A+ KG V+ L Sbjct: 176 IDCQDPKGRTPLLWAAYQGDSLSVMLLLKFGASTKIVDEGGFTPLHWATVKGQPYVLTHL 235 Query: 444 LASGASVKAKNRKG 485 + GA K G Sbjct: 236 IRDGADFFLKTNDG 249
>YR886_MIMIV (Q5UQY4) Putative ankyrin repeat protein R886 (Fragment)| Length = 130 Score = 44.7 bits (104), Expect = 2e-04 Identities = 20/47 (42%), Positives = 32/47 (68%) Frame = +3 Query: 405 ASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLV 545 +S+ G+ E+V+ L+ +GA + A N GFT L +++N H E+VK LV Sbjct: 29 SSEYGNFEIVKYLIDNGADITAINEYGFTPLDLSSKNGHYEIVKLLV 75 Score = 40.4 bits (93), Expect = 0.004 Identities = 25/83 (30%), Positives = 41/83 (49%), Gaps = 1/83 (1%) Frame = +3 Query: 318 GHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASV-KAKNRKGFTA 494 G+ ++VK L + + +S+ GH E+V+ L+ AS+ K N Sbjct: 33 GNFEIVKYLIDNGADITAINEYGFTPLDLSSKNGHYEIVKLLVECRASIIKTDN----LT 88 Query: 495 LHFAAQNSHLELVKYLVRRGVDI 563 L A++N H+++VK LV G DI Sbjct: 89 LILASENGHIKIVKLLVENGADI 111 Score = 35.8 bits (81), Expect = 0.088 Identities = 26/99 (26%), Positives = 49/99 (49%), Gaps = 2/99 (2%) Frame = +3 Query: 186 DLKLHKAARSGDAAAVESLCDS--DPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKX 359 D + ++ G+ V+ L D+ D A+N TPL L++ GH ++VK L + + Sbjct: 23 DRTIINSSEYGNFEIVKYLIDNGADITAINE---YGFTPLDLSSKNGHYEIVKLLVECR- 78 Query: 360 XXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKN 476 + AS+ GH+++V+ L+ +GA ++ N Sbjct: 79 --ASIIKTDNLTLILASENGHIKIVKLLVENGADIRYHN 115
>PP16B_MOUSE (Q8VHQ3) Protein phosphatase 1 regulatory inhibitor subunit 16B| (TGF-beta-inhibited membrane-associated protein) (CAAX box protein TIMAP) Length = 568 Score = 44.7 bits (104), Expect = 2e-04 Identities = 27/86 (31%), Positives = 42/86 (48%) Frame = +3 Query: 306 AAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKG 485 A+ + V+ K+K +H E+V+ LL+ GA+V AK+ + Sbjct: 75 ASLRNDAEEVRYFLKNKVSPDLCNEDGLTALHQCCIDNFEEIVKLLLSHGANVNAKDNEL 134 Query: 486 FTALHFAAQNSHLELVKYLVRRGVDI 563 +T LH AA H+ LVK LV+ G D+ Sbjct: 135 WTPLHAAATCGHINLVKILVQYGADL 160 Score = 35.4 bits (80), Expect = 0.11 Identities = 27/129 (20%), Positives = 48/129 (37%), Gaps = 29/129 (22%) Frame = +3 Query: 264 LNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRE- 440 +N++D TPLH AA GH+++VK L ++ + L+V+ Sbjct: 127 VNAKDNELWTPLHAAATCGHINLVKILVQYGADLLAVNSDGNMPYDLCEDEPTLDVIETC 186 Query: 441 ----------------------------LLASGASVKAKNRKGFTALHFAAQNSHLELVK 536 ++A+G + + +G T LH A N +L + Sbjct: 187 MAYQGITQEKINEMRAAPEQKMISDIHCMIAAGQDLDWIDGQGATLLHIAGANGYLRAAE 246 Query: 537 YLVRRGVDI 563 L+ GV + Sbjct: 247 LLLDHGVRV 255 Score = 32.3 bits (72), Expect = 0.97 Identities = 17/57 (29%), Positives = 26/57 (45%) Frame = +3 Query: 396 IHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDIT 566 +H A G+L LL G V K+ G+ LH AA + + + LV G ++ Sbjct: 233 LHIAGANGYLRAAELLLDHGVRVDVKDWDGWEPLHAAAFWGQMPMAELLVSHGASLS 289 Score = 31.2 bits (69), Expect = 2.2 Identities = 22/82 (26%), Positives = 32/82 (39%) Frame = +3 Query: 240 LCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKG 419 LC+ D L T LH ++VK L H +H A+ G Sbjct: 96 LCNEDGL----------TALHQCCIDNFEEIVKLLLSHGANVNAKDNELWTPLHAAATCG 145 Query: 420 HLEVVRELLASGASVKAKNRKG 485 H+ +V+ L+ GA + A N G Sbjct: 146 HINLVKILVQYGADLLAVNSDG 167
>PP16B_BOVIN (Q95N27) Protein phosphatase 1 regulatory inhibitor subunit 16B| (TGF-beta-inhibited membrane-associated protein) (bTIMAP) (CAAX box protein TIMAP) Length = 568 Score = 44.7 bits (104), Expect = 2e-04 Identities = 27/86 (31%), Positives = 42/86 (48%) Frame = +3 Query: 306 AAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKG 485 A+ + V+ K+K +H E+V+ LL+ GA+V AK+ + Sbjct: 75 ASLRNDAEEVRYFLKNKVSPDLCNEDGLTALHQCCIDNFEEIVKLLLSHGANVNAKDNEL 134 Query: 486 FTALHFAAQNSHLELVKYLVRRGVDI 563 +T LH AA H+ LVK LV+ G D+ Sbjct: 135 WTPLHAAATCGHINLVKILVQYGADL 160 Score = 36.2 bits (82), Expect = 0.067 Identities = 27/129 (20%), Positives = 48/129 (37%), Gaps = 29/129 (22%) Frame = +3 Query: 264 LNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRE- 440 +N++D TPLH AA GH+++VK L ++ + L+V+ Sbjct: 127 VNAKDNELWTPLHAAATCGHINLVKILVQYGADLLAVNSDGNMPYDLCEDEPTLDVIETC 186 Query: 441 ----------------------------LLASGASVKAKNRKGFTALHFAAQNSHLELVK 536 ++A+G + + +G T LH A N +L + Sbjct: 187 MAYQGITQEKINEMRAAPEQQMISDIHCMIAAGQDLDWVDAQGATLLHIAGANGYLRAAE 246 Query: 537 YLVRRGVDI 563 L+ GV + Sbjct: 247 LLLDHGVRV 255 Score = 33.5 bits (75), Expect = 0.44 Identities = 17/57 (29%), Positives = 27/57 (47%) Frame = +3 Query: 396 IHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDIT 566 +H A G+L LL G V K+ G+ LH AA +++ + LV G ++ Sbjct: 233 LHIAGANGYLRAAELLLDHGVRVDVKDWDGWEPLHAAAFWGQMQMAELLVSHGASLS 289 Score = 31.2 bits (69), Expect = 2.2 Identities = 22/82 (26%), Positives = 32/82 (39%) Frame = +3 Query: 240 LCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKG 419 LC+ D L T LH ++VK L H +H A+ G Sbjct: 96 LCNEDGL----------TALHQCCIDNFEEIVKLLLSHGANVNAKDNELWTPLHAAATCG 145 Query: 420 HLEVVRELLASGASVKAKNRKG 485 H+ +V+ L+ GA + A N G Sbjct: 146 HINLVKILVQYGADLLAVNSDG 167
>ASB13_MOUSE (Q8VBX0) Ankyrin repeat and SOCS box protein 13 (ASB-13)| Length = 278 Score = 44.7 bits (104), Expect = 2e-04 Identities = 30/94 (31%), Positives = 44/94 (46%) Frame = +3 Query: 282 LSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGAS 461 + RTP+H AA G ++ L +H AS +G + V+ LLA+GA Sbjct: 18 VERTPVHEAAQRGESLQLQQLIDSGACVNQVTVDSITPLHAASLQGQAQCVQLLLAAGAQ 77 Query: 462 VKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 V A+N G T L A + +E VK L+ G + Sbjct: 78 VDARNIDGSTPLCDACASGSIECVKLLLSYGAKV 111 Score = 39.7 bits (91), Expect = 0.006 Identities = 26/97 (26%), Positives = 46/97 (47%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH+A SG + V L D L + D TPLH+A H+D VK L + Sbjct: 121 LHEACMSGSSECVRLLIDVGA-NLEAHDCHFGTPLHVACAREHLDCVKVLL-NAGANVNA 178 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKG 485 +H A++ +++++ L+ G ++ A++ +G Sbjct: 179 AKLHETALHHAAKVKNVDLIEMLIEFGGNIYARDNRG 215
>ASB13_HUMAN (Q8WXK3) Ankyrin repeat and SOCS box protein 13 (ASB-13)| Length = 278 Score = 44.7 bits (104), Expect = 2e-04 Identities = 30/94 (31%), Positives = 44/94 (46%) Frame = +3 Query: 282 LSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGAS 461 + RTP+H AA G ++ L + +H AS +G V+ LLA+GA Sbjct: 18 VERTPVHEAAQRGESLQLQQLIESGACVNQVTVDSITPLHAASLQGQARCVQLLLAAGAQ 77 Query: 462 VKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 V A+N G T L A + +E VK L+ G + Sbjct: 78 VDARNIDGSTPLCDACASGSIECVKLLLSYGAKV 111 Score = 39.7 bits (91), Expect = 0.006 Identities = 26/97 (26%), Positives = 46/97 (47%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH+A SG + V L D L + D TPLH+A H+D VK L + Sbjct: 121 LHEACMSGSSECVRLLIDVGA-NLEAHDCHFGTPLHVACAREHLDCVKVLL-NAGANVNA 178 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKG 485 +H A++ +++++ L+ G ++ A++ +G Sbjct: 179 AKLHETALHHAAKVKNVDLIEMLIEFGGNIYARDNRG 215
>YR846_MIMIV (Q5UP13) Putative ankyrin repeat protein R846| Length = 170 Score = 44.7 bits (104), Expect = 2e-04 Identities = 21/54 (38%), Positives = 31/54 (57%) Frame = +3 Query: 405 ASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDIT 566 A + GHLE+V+ L++ GA + N A+ N H E+V+YL+ G DIT Sbjct: 119 ACENGHLEMVKYLVSQGADITVDNNYSIMK---ASSNGHFEMVQYLINEGADIT 169 Score = 43.9 bits (102), Expect = 3e-04 Identities = 22/50 (44%), Positives = 34/50 (68%) Frame = +3 Query: 417 GHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDIT 566 G +E+V+ L+ GA++K ++ A+ A +N HLE+VKYLV +G DIT Sbjct: 93 GLIEIVKYLIILGANIKERDN---IAVGKACENGHLEMVKYLVSQGADIT 139
>ZDH13_MACFA (Q4R690) Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc| finger DHHC domain-containing protein 13) (DHHC-13) Length = 622 Score = 44.7 bits (104), Expect = 2e-04 Identities = 29/100 (29%), Positives = 52/100 (52%), Gaps = 3/100 (3%) Frame = +3 Query: 276 DRLSRTPLHLAAWAGHVDVVKC-LCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLAS 452 D+ + + LH AA +D+VK + K +H+A ++GHL +V LL Sbjct: 79 DKENVSLLHWAAINNRLDLVKFYISKGAVVDQLGGDLNSTPLHWAIRQGHLPMVILLLQH 138 Query: 453 GASVKAKNRKGFTALHFAAQNSHLELVKYLV--RRGVDIT 566 GA + +GF+++H A H+ ++ YL+ R+ V++T Sbjct: 139 GADPTLTDGEGFSSIHLAVLFQHMPIIAYLISKRQSVNMT 178 Score = 39.7 bits (91), Expect = 0.006 Identities = 18/50 (36%), Positives = 33/50 (66%) Frame = +3 Query: 405 ASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 A+Q G E +EL+ +G V+ +++ + LH+AA N+ L+LVK+ + +G Sbjct: 56 ATQYGIFERCKELVEAGYDVRQPDKENVSLLHWAAINNRLDLVKFYISKG 105 Score = 36.2 bits (82), Expect = 0.067 Identities = 22/76 (28%), Positives = 33/76 (43%) Frame = +3 Query: 282 LSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGAS 461 L+ TPLH A GH+ +V L +H IH A H+ ++ L++ S Sbjct: 115 LNSTPLHWAIRQGHLPMVILLLQHGADPTLTDGEGFSSIHLAVLFQHMPIIAYLISKRQS 174 Query: 462 VKAKNRKGFTALHFAA 509 V + G T L +A Sbjct: 175 VNMTDVNGQTPLMLSA 190
>PP16B_HUMAN (Q96T49) Protein phosphatase 1 regulatory inhibitor subunit 16B| (TGF-beta-inhibited membrane-associated protein) (hTIMAP) (CAAX box protein TIMAP) (Ankyrin repeat domain protein 4) Length = 567 Score = 44.7 bits (104), Expect = 2e-04 Identities = 27/86 (31%), Positives = 42/86 (48%) Frame = +3 Query: 306 AAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKG 485 A+ + V+ K+K +H E+V+ LL+ GA+V AK+ + Sbjct: 75 ASLRNDAEEVRYFLKNKVSPDLCNEDGLTALHQCCIDNFEEIVKLLLSHGANVNAKDNEL 134 Query: 486 FTALHFAAQNSHLELVKYLVRRGVDI 563 +T LH AA H+ LVK LV+ G D+ Sbjct: 135 WTPLHAAATCGHINLVKILVQYGADL 160 Score = 35.8 bits (81), Expect = 0.088 Identities = 27/129 (20%), Positives = 48/129 (37%), Gaps = 29/129 (22%) Frame = +3 Query: 264 LNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRE- 440 +N++D TPLH AA GH+++VK L ++ + L+V+ Sbjct: 127 VNAKDNELWTPLHAAATCGHINLVKILVQYGADLLAVNSDGNMPYDLCEDEPTLDVIETC 186 Query: 441 ----------------------------LLASGASVKAKNRKGFTALHFAAQNSHLELVK 536 ++A+G + + +G T LH A N +L + Sbjct: 187 MAYQGITQEKINEMRVAPEQQMIADIHCMIAAGQDLDWIDAQGATLLHIAGANGYLRAAE 246 Query: 537 YLVRRGVDI 563 L+ GV + Sbjct: 247 LLLDHGVRV 255 Score = 33.5 bits (75), Expect = 0.44 Identities = 17/57 (29%), Positives = 27/57 (47%) Frame = +3 Query: 396 IHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDIT 566 +H A G+L LL G V K+ G+ LH AA +++ + LV G ++ Sbjct: 233 LHIAGANGYLRAAELLLDHGVRVDVKDWDGWEPLHAAAFWGQMQMAELLVSHGASLS 289 Score = 31.2 bits (69), Expect = 2.2 Identities = 22/82 (26%), Positives = 32/82 (39%) Frame = +3 Query: 240 LCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKG 419 LC+ D L T LH ++VK L H +H A+ G Sbjct: 96 LCNEDGL----------TALHQCCIDNFEEIVKLLLSHGANVNAKDNELWTPLHAAATCG 145 Query: 420 HLEVVRELLASGASVKAKNRKG 485 H+ +V+ L+ GA + A N G Sbjct: 146 HINLVKILVQYGADLLAVNSDG 167
>KRIT1_HUMAN (O00522) Krev interaction trapped protein 1 (Krev interaction| trapped 1) (Cerebral cavernous malformations 1 protein) Length = 736 Score = 44.7 bits (104), Expect = 2e-04 Identities = 28/88 (31%), Positives = 42/88 (47%), Gaps = 1/88 (1%) Frame = +3 Query: 186 DLKLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLC-KHKXX 362 D LH++A GD+ + L S+ ++N D P+H A W G V+ + L K K Sbjct: 289 DFPLHRSACEGDSELLSRLL-SERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCN 347 Query: 363 XXXXXXXXXXXIHFASQKGHLEVVRELL 446 +HFA+ GH E+V+ LL Sbjct: 348 PNLLNGQLSSPLHFAAGGGHAEIVQILL 375 Score = 37.7 bits (86), Expect = 0.023 Identities = 25/85 (29%), Positives = 38/85 (44%), Gaps = 1/85 (1%) Frame = +3 Query: 294 PLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASG-ASVKA 470 PLH +A G +++ L + IH+A G +E R LL G + Sbjct: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350 Query: 471 KNRKGFTALHFAAQNSHLELVKYLV 545 N + + LHFAA H E+V+ L+ Sbjct: 351 LNGQLSSPLHFAAGGGHAEIVQILL 375 Score = 30.0 bits (66), Expect = 4.8 Identities = 16/53 (30%), Positives = 23/53 (43%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKH 353 +H A G A L + N + +PLH AA GH ++V+ L H Sbjct: 325 IHYACWYGKVEATRILLEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILLNH 377
>YL059_MIMIV (Q5UPD5) Putative ankyrin repeat protein L59| Length = 307 Score = 44.7 bits (104), Expect = 2e-04 Identities = 39/126 (30%), Positives = 57/126 (45%) Frame = +3 Query: 186 DLKLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXX 365 D + AAR+G V L S + + D + L AA GH+++VK L Sbjct: 160 DFAIKYAARNGHFKLVRYL-HSQGSDIRTDDDYA---LRWAARNGHLEIVKYL---HSKG 212 Query: 366 XXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLV 545 I +AS G+LE+V L G ++ N + +AA N HLE+V+YL Sbjct: 213 CNIHAYGDSAIKWASMGGYLEIVEYLHGVGCDIRIDNDY---PIRWAASNGHLEVVEYLF 269 Query: 546 RRGVDI 563 +G DI Sbjct: 270 SQGCDI 275 Score = 40.8 bits (94), Expect = 0.003 Identities = 24/58 (41%), Positives = 35/58 (60%) Frame = +3 Query: 396 IHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDITT 569 + +A+ G LE+V L G V+ NR F A+ +AA+N H +LV+YL +G DI T Sbjct: 133 LRWAALSGCLEMVEYLQTQGCDVR--NRNDF-AIKYAARNGHFKLVRYLHSQGSDIRT 187 Score = 37.7 bits (86), Expect = 0.023 Identities = 20/50 (40%), Positives = 30/50 (60%) Frame = +3 Query: 396 IHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLV 545 I +A+ GHLEVV L + G + A N AL +A +N H ++V+Y+V Sbjct: 253 IRWAASNGHLEVVEYLFSQGCDIGADNN---YALMWAKKNGHDDVVEYIV 299
>ASB14_MOUSE (Q8VHS7) Ankyrin repeat and SOCS box protein 14 (ASB-14)| Length = 433 Score = 44.3 bits (103), Expect = 2e-04 Identities = 21/53 (39%), Positives = 36/53 (67%) Frame = +3 Query: 396 IHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 +H A++ G L++V+ +LASGA A++ GFT L AAQ H +++ L+++G Sbjct: 23 LHEAAKLGRLDMVKLMLASGAYPDARSSYGFTPLALAAQGGHTGIMQLLLQKG 75 Score = 37.7 bits (86), Expect = 0.023 Identities = 35/128 (27%), Positives = 50/128 (39%), Gaps = 11/128 (8%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH+AA+ G V+ + S ++R TPL LAA GH +++ L + K Sbjct: 23 LHEAAKLGRLDMVKLMLASGAYP-DARSSYGFTPLALAAQGGHTGIMQLLLQ-KGKAYLM 80 Query: 375 XXXXXXXIHF-----------ASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSH 521 +H A + G+ E V LL GA G +H AA H Sbjct: 81 VDYRGADVHSQASDSSSVLLEAVRGGNPEAVSLLLEYGADANIPKSSGHLPIHVAADKGH 140 Query: 522 LELVKYLV 545 +K LV Sbjct: 141 FLALKVLV 148
>ZDH13_HUMAN (Q8IUH4) Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc| finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein) (Huntingtin-interacting protein HIP3RP) (Putativ Length = 622 Score = 44.3 bits (103), Expect = 2e-04 Identities = 26/97 (26%), Positives = 49/97 (50%), Gaps = 1/97 (1%) Frame = +3 Query: 276 DRLSRTPLHLAAWAGHVDVVKC-LCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLAS 452 D+ + + LH AA +D+V+ + K +H+A ++GHL +V LL Sbjct: 79 DKENVSLLHWAAINNRLDLVRFYISKGAVVDQLGGDLNSTPLHWAIRQGHLPMVILLLQH 138 Query: 453 GASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 GA + +GF+++H A H+ ++ YL+ +G + Sbjct: 139 GADPTLIDGEGFSSIHLAVLFQHMPIIAYLISKGQSV 175 Score = 38.9 bits (89), Expect = 0.010 Identities = 23/76 (30%), Positives = 34/76 (44%) Frame = +3 Query: 282 LSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGAS 461 L+ TPLH A GH+ +V L +H IH A H+ ++ L++ G S Sbjct: 115 LNSTPLHWAIRQGHLPMVILLLQHGADPTLIDGEGFSSIHLAVLFQHMPIIAYLISKGQS 174 Query: 462 VKAKNRKGFTALHFAA 509 V + G T L +A Sbjct: 175 VNMTDVNGQTPLMLSA 190 Score = 33.1 bits (74), Expect = 0.57 Identities = 19/58 (32%), Positives = 32/58 (55%), Gaps = 1/58 (1%) Frame = +3 Query: 396 IHFASQKGHLEVVRELLASGASV-KAKNRKGFTALHFAAQNSHLELVKYLVRRGVDIT 566 +H+A+ L++VR ++ GA V + T LH+A + HL +V L++ G D T Sbjct: 86 LHWAAINNRLDLVRFYISKGAVVDQLGGDLNSTPLHWAIRQGHLPMVILLLQHGADPT 143
>CACT_DROME (Q03017) NF-kappa-B inhibitor cactus| Length = 500 Score = 44.3 bits (103), Expect = 2e-04 Identities = 28/90 (31%), Positives = 41/90 (45%), Gaps = 3/90 (3%) Frame = +3 Query: 291 TPLHLAAWAGHVDVVKCLCK---HKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGAS 461 TPLHLA +G VDVV L + H +H A+ ++R LL +GA Sbjct: 232 TPLHLACISGSVDVVAALIRMAPHPCLLNIQNDVAQTPLHLAALTAQPNIMRILLLAGAE 291 Query: 462 VKAKNRKGFTALHFAAQNSHLELVKYLVRR 551 ++R G TALH + + V+ L + Sbjct: 292 PTVRDRHGNTALHLSCIAGEKQCVRALTEK 321 Score = 43.1 bits (100), Expect = 5e-04 Identities = 36/158 (22%), Positives = 59/158 (37%), Gaps = 32/158 (20%) Frame = +3 Query: 186 DLKLHKAARSGDAAAVESLCDS--DPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKX 359 D LH A SG V +L P LN ++ +++TPLHLAA ++++ L Sbjct: 231 DTPLHLACISGSVDVVAALIRMAPHPCLLNIQNDVAQTPLHLAALTAQPNIMRILLLAGA 290 Query: 360 XXXXXXXXXXXXIHFASQKGHLEVVRELLAS----------------------------- 452 +H + G + VR L Sbjct: 291 EPTVRDRHGNTALHLSCIAGEKQCVRALTEKFGATEIHEAHRQYGHRSNDKAVSSLSYAC 350 Query: 453 -GASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 A ++ +N G +H AA+ H+++++ LV G DI Sbjct: 351 LPADLEIRNYDGERCVHLAAEAGHIDILRILVSHGADI 388 Score = 39.7 bits (91), Expect = 0.006 Identities = 17/51 (33%), Positives = 33/51 (64%), Gaps = 1/51 (1%) Frame = +3 Query: 396 IHFASQKGHLEVVRELLASGASVKAKNRK-GFTALHFAAQNSHLELVKYLV 545 +H A++ GH++++R L++ GA + A+ K G T LH A + + +L +L+ Sbjct: 366 VHLAAEAGHIDILRILVSHGADINAREGKSGRTPLHIAIEGCNEDLANFLL 416 Score = 34.7 bits (78), Expect = 0.20 Identities = 30/123 (24%), Positives = 48/123 (39%), Gaps = 3/123 (2%) Frame = +3 Query: 210 RSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXX 389 RS D A P L R+ +HLAA AGH+D+++ L H Sbjct: 337 RSNDKAVSSLSYACLPADLEIRNYDGERCVHLAAEAGHIDILRILVSHGADINAREGKSG 396 Query: 390 XX-IHFASQKGHLEVVRELL--ASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVD 560 +H A + + ++ LL +++ G TA FA + + L +RG + Sbjct: 397 RTPLHIAIEGCNEDLANFLLDECEKLNLETATYAGLTAYQFACIMNKSRMQNILEKRGAE 456 Query: 561 ITT 569 T Sbjct: 457 TVT 459
>AKR1_YEAST (P39010) Palmitoyltransferase AKR1 (EC 2.3.1.-) (Ankyrin| repeat-containing protein AKR1) Length = 764 Score = 44.3 bits (103), Expect = 2e-04 Identities = 42/161 (26%), Positives = 62/161 (38%), Gaps = 39/161 (24%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSR-DRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXX 371 LH A+ + + V+ L S +N+R L TPLH AA G+V +V L KH Sbjct: 113 LHWASINNRLSVVDFLV-SQGADVNARAGALHATPLHWAARYGYVYIVDFLLKHGADPTM 171 Query: 372 XXXXXXXXIH--------------------------------------FASQKGHLEVVR 437 +H +A+ +G V Sbjct: 172 TDDQGFNLLHLSVNSSNIMLVLYVLFNVVSKGLLDIDCRDPKGRTSLLWAAYQGDSLTVA 231 Query: 438 ELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVD 560 ELL GAS+K + +GFT LH+ ++KYL++ G D Sbjct: 232 ELLKFGASIKIADTEGFTPLHWGTVKGQPHVLKYLIQDGAD 272 Score = 43.5 bits (101), Expect = 4e-04 Identities = 31/121 (25%), Positives = 55/121 (45%), Gaps = 3/121 (2%) Frame = +3 Query: 192 KLHKAARSGDAAAVESLCDSDPLALNSRDRLSR--TPLHLAAWAGHVDVVKCLCKHKXXX 365 + H A + GD A V+ + L +N+ + T LH A+ + VV L Sbjct: 76 RYHTACQRGDLATVKEMIHGKLLEVNNDGDSTEHITGLHWASINNRLSVVDFLVSQGADV 135 Query: 366 XXXXXXXXXX-IHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYL 542 +H+A++ G++ +V LL GA + +GF LH + +S++ LV Y+ Sbjct: 136 NARAGALHATPLHWAARYGYVYIVDFLLKHGADPTMTDDQGFNLLHLSVNSSNIMLVLYV 195 Query: 543 V 545 + Sbjct: 196 L 196 Score = 39.7 bits (91), Expect = 0.006 Identities = 38/130 (29%), Positives = 55/130 (42%), Gaps = 8/130 (6%) Frame = +3 Query: 201 KAARSGDAAAVESLCDSDPLALNSRDRLSRTPL----HLAAWAGHVDVVKCLCKHKXXXX 368 KA RSG+ +S +N D PL H A G + VK + K Sbjct: 47 KAIRSGNEE------ESGNEQVNHNDEAEEDPLLTRYHTACQRGDLATVKEMIHGKLLEV 100 Query: 369 XXXXXXXXXI---HFASQKGHLEVVRELLASGASVKAK-NRKGFTALHFAAQNSHLELVK 536 I H+AS L VV L++ GA V A+ T LH+AA+ ++ +V Sbjct: 101 NNDGDSTEHITGLHWASINNRLSVVDFLVSQGADVNARAGALHATPLHWAARYGYVYIVD 160 Query: 537 YLVRRGVDIT 566 +L++ G D T Sbjct: 161 FLLKHGADPT 170
>ACBD6_BRARE (Q4V8X4) Acyl-CoA-binding domain-containing protein 6| Length = 300 Score = 44.3 bits (103), Expect = 2e-04 Identities = 19/55 (34%), Positives = 36/55 (65%) Frame = +3 Query: 396 IHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVD 560 +H+A +GH ++V LL + A + +++ +G TALH+A+ E+V+ L++ G D Sbjct: 214 LHWACDRGHKDLVSLLLQNNADINSQDDEGQTALHYASACEFAEIVELLLKAGAD 268 Score = 44.3 bits (103), Expect = 2e-04 Identities = 27/100 (27%), Positives = 42/100 (42%) Frame = +3 Query: 186 DLKLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXX 365 D + R + V S + +N+RD R LH A GH D+V L ++ Sbjct: 177 DKNIFDYCRENNIEHVSKAISSKTVDVNTRDEEGRALLHWACDRGHKDLVSLLLQNNADI 236 Query: 366 XXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKG 485 +H+AS E+V LL +GA K+++G Sbjct: 237 NSQDDEGQTALHYASACEFAEIVELLLKAGADPSIKDQEG 276
>UACA_MOUSE (Q8CGB3) Uveal autoantigen with coiled-coil domains and ankyrin| repeats protein (Nucling) (Nuclear membrane-binding protein) Length = 1411 Score = 44.3 bits (103), Expect = 2e-04 Identities = 32/124 (25%), Positives = 53/124 (42%) Frame = +3 Query: 195 LHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXX 374 LH AA+ G A ++ L + D RT LH A A ++ LC H Sbjct: 107 LHLAAKYGHALCLQKLLQYN-CPTEHVDLQGRTALHDAVMADCPSSIQLLCDHGASVNAK 165 Query: 375 XXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRG 554 + A+Q + + L+ GA V +++++ TAL + + V+ LV+ G Sbjct: 166 DIDGRTPLVLATQMCRPTICQLLIDRGADVNSRDKQNRTALMLGCEYGCRDAVEVLVKNG 225 Query: 555 VDIT 566 D+T Sbjct: 226 ADLT 229 Score = 44.3 bits (103), Expect = 2e-04 Identities = 29/126 (23%), Positives = 51/126 (40%) Frame = +3 Query: 186 DLKLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXX 365 D +L KAA GD V S+ + D R+ H+ A G+++ + + H Sbjct: 37 DDRLMKAAERGDVEKVSSILAKKGVHPGKLDVEGRSAFHVVASKGNLECLNAILTHGIDV 96 Query: 366 XXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLV 545 +H A++ GH +++LL + + +G TALH A ++ L Sbjct: 97 ATRDSAGRNALHLAAKYGHALCLQKLLQYNCPTEHVDLQGRTALHDAVMADCPSSIQLLC 156 Query: 546 RRGVDI 563 G + Sbjct: 157 DHGASV 162 Score = 42.4 bits (98), Expect = 0.001 Identities = 32/124 (25%), Positives = 53/124 (42%) Frame = +3 Query: 198 HKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXX 377 H A G+ + ++ + + + +RD R LHLAA GH ++ L ++ Sbjct: 75 HVVASKGNLECLNAIL-THGIDVATRDSAGRNALHLAAKYGHALCLQKLLQYNCPTEHVD 133 Query: 378 XXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGV 557 +H A ++ L GASV AK+ G T L A Q + + L+ RG Sbjct: 134 LQGRTALHDAVMADCPSSIQLLCDHGASVNAKDIDGRTPLVLATQMCRPTICQLLIDRGA 193 Query: 558 DITT 569 D+ + Sbjct: 194 DVNS 197 Score = 30.8 bits (68), Expect = 2.8 Identities = 16/56 (28%), Positives = 30/56 (53%), Gaps = 1/56 (1%) Frame = +3 Query: 405 ASQKGHLEVVRELLAS-GASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDITT 569 A+++G +E V +LA G + +G +A H A +LE + ++ G+D+ T Sbjct: 43 AAERGDVEKVSSILAKKGVHPGKLDVEGRSAFHVVASKGNLECLNAILTHGIDVAT 98
>ANR13_MOUSE (Q80UP5) Ankyrin repeat domain-containing protein 13| Length = 588 Score = 44.3 bits (103), Expect = 2e-04 Identities = 28/89 (31%), Positives = 40/89 (44%) Frame = +3 Query: 267 NSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELL 446 ++RD SR PLHL W + ++ + + +H A GHLE R LL Sbjct: 3 SARDTSSRFPLHLLVWNNDYEQLEKELRDQNAEALDPRGRTL-LHLAVSLGHLESARVLL 61 Query: 447 ASGASVKAKNRKGFTALHFAAQNSHLELV 533 A V +N +G+T LH A E+V Sbjct: 62 RHKADVTKENGQGWTVLHEAVSTGDPEMV 90 Score = 33.1 bits (74), Expect = 0.57 Identities = 26/85 (30%), Positives = 37/85 (43%), Gaps = 1/85 (1%) Frame = +3 Query: 195 LHKAARSGDAAAVES-LCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXX 371 LH + D +E L D + AL+ R RT LHLA GH++ + L +HK Sbjct: 13 LHLLVWNNDYEQLEKELRDQNAEALDPR---GRTLLHLAVSLGHLESARVLLRHKADVTK 69 Query: 372 XXXXXXXXIHFASQKGHLEVVRELL 446 +H A G E+V +L Sbjct: 70 ENGQGWTVLHEAVSTGDPEMVYTVL 94
>AKT2_ARATH (Q38898) Potassium channel AKT2/3| Length = 802 Score = 44.3 bits (103), Expect = 2e-04 Identities = 36/148 (24%), Positives = 61/148 (41%), Gaps = 31/148 (20%) Frame = +3 Query: 213 SGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKH------------- 353 +G+AA ++ L + L+ + D +TPLH+AA G+ D V L KH Sbjct: 551 TGNAALLDELLKAK-LSPDITDSKGKTPLHVAASRGYEDCVLVLLKHGCNIHIRDVNGNS 609 Query: 354 ---KXXXXXXXXXXXXXIHF---------------ASQKGHLEVVRELLASGASVKAKNR 479 + HF A+++ ++EV++ LL G +V ++ Sbjct: 610 ALWEAIISKHYEIFRILYHFAAISDPHIAGDLLCEAAKQNNVEVMKALLKQGLNVDTEDH 669 Query: 480 KGFTALHFAAQNSHLELVKYLVRRGVDI 563 G TAL A +++V L G D+ Sbjct: 670 HGVTALQVAMAEDQMDMVNLLATNGADV 697
>POT22_HUMAN (Q6S545) Prostate, ovary, testis expressed protein on chromosome 22| Length = 288 Score = 43.9 bits (102), Expect = 3e-04 Identities = 32/108 (29%), Positives = 45/108 (41%) Frame = +3 Query: 192 KLHKAARSGDAAAVESLCDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXXX 371 KLH+AA G + + +N +D+ RT LHLA+ G+ +VVK L + Sbjct: 179 KLHRAAWWGKVPRKDLIVMLKDTDMNKKDKQKRTALHLASANGNSEVVKLLLDRRCQLNV 238 Query: 372 XXXXXXXXIHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQN 515 + A Q E LL G + G TALH+A N Sbjct: 239 LDNKKRTALTKAVQCQEDECALMLLEHGTDPNIPDEYGNTALHYAIYN 286 Score = 32.3 bits (72), Expect = 0.97 Identities = 27/89 (30%), Positives = 34/89 (38%), Gaps = 1/89 (1%) Frame = +3 Query: 297 LHLAAWAGHVDVVKCLCKHKXXXXXXXXXXX-XXIHFASQKGHLEVVRELLASGASVKAK 473 LH AAW G V + K +H AS G+ EVV+ LL + Sbjct: 180 LHRAAWWGKVPRKDLIVMLKDTDMNKKDKQKRTALHLASANGNSEVVKLLLDRRCQLNVL 239 Query: 474 NRKGFTALHFAAQNSHLELVKYLVRRGVD 560 + K TAL A Q E L+ G D Sbjct: 240 DNKKRTALTKAVQCQEDECALMLLEHGTD 268
>ASB10_HUMAN (Q8WXI3) Ankyrin repeat and SOCS box protein 10 (ASB-10)| Length = 429 Score = 43.9 bits (102), Expect = 3e-04 Identities = 27/91 (29%), Positives = 40/91 (43%) Frame = +3 Query: 291 TPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKA 470 TPLH+AA GH +V++ L + + +H A GH V LL +GA Sbjct: 118 TPLHVAASRGHTEVLRLLLRRRARPDSAPGGRTA-LHEACAAGHTACVHVLLVAGADPNI 176 Query: 471 KNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 ++ G LH LE + L+R G + Sbjct: 177 ADQDGKRPLHLCRGPGTLECAELLLRFGARV 207 Score = 42.4 bits (98), Expect = 0.001 Identities = 31/104 (29%), Positives = 48/104 (46%), Gaps = 3/104 (2%) Frame = +3 Query: 195 LHKAARSGDAAAVESL--CDSDPLALNSRDRLSRTPLHLAAWAGHVDVVKCLCKHKXXXX 368 LH+A +G A V L +DP N D+ + PLHL G ++ + L + Sbjct: 152 LHEACAAGHTACVHVLLVAGADP---NIADQDGKRPLHLCRGPGTLECAELLLRFGARVD 208 Query: 369 XXXXXXXXX-IHFASQKGHLEVVRELLASGASVKAKNRKGFTAL 497 +H A++ GH+E+ LL GA A+N +G+T L Sbjct: 209 GRSEEEEETPLHVAARLGHVELADLLLRRGACPDARNAEGWTPL 252 Score = 42.0 bits (97), Expect = 0.001 Identities = 31/90 (34%), Positives = 38/90 (42%), Gaps = 1/90 (1%) Frame = +3 Query: 288 RTPLHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVK 467 RT LH A AGH V L +H G LE LL GA V Sbjct: 149 RTALHEACAAGHTACVHVLLVAGADPNIADQDGKRPLHLCRGPGTLECAELLLRFGARVD 208 Query: 468 AKNRKGF-TALHFAAQNSHLELVKYLVRRG 554 ++ + T LH AA+ H+EL L+RRG Sbjct: 209 GRSEEEEETPLHVAARLGHVELADLLLRRG 238 Score = 33.1 bits (74), Expect = 0.57 Identities = 16/39 (41%), Positives = 21/39 (53%) Frame = +3 Query: 396 IHFASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQ 512 +H A ++GH VV LL+ G S + G T LH A Q Sbjct: 298 LHLACRRGHAAVVELLLSCGVSANTMDYGGHTPLHCALQ 336
>YR838_MIMIV (Q5UQI7) Putative ankyrin repeat protein R838| Length = 276 Score = 43.9 bits (102), Expect = 3e-04 Identities = 21/53 (39%), Positives = 33/53 (62%) Frame = +3 Query: 405 ASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDI 563 A++KGH++VV+ LL GA + + N L +AA E+VK+L+ RG D+ Sbjct: 172 AAEKGHIDVVKLLLEKGADISSHNH---WPLSYAALEGKFEMVKFLISRGADV 221 Score = 41.6 bits (96), Expect = 0.002 Identities = 25/83 (30%), Positives = 42/83 (50%) Frame = +3 Query: 297 LHLAAWAGHVDVVKCLCKHKXXXXXXXXXXXXXIHFASQKGHLEVVRELLASGASVKAKN 476 L AA GH+DVVK L + + +A+ +G E+V+ L++ GA V+AKN Sbjct: 169 LRSAAEKGHIDVVKLLLE---KGADISSHNHWPLSYAALEGKFEMVKFLISRGADVRAKN 225 Query: 477 RKGFTALHFAAQNSHLELVKYLV 545 + + +A H E+ Y++ Sbjct: 226 ---YNPIKYALDGGHREIADYML 245 Score = 33.9 bits (76), Expect = 0.33 Identities = 18/55 (32%), Positives = 32/55 (58%) Frame = +3 Query: 405 ASQKGHLEVVRELLASGASVKAKNRKGFTALHFAAQNSHLELVKYLVRRGVDITT 569 A++ G+ EVV L+ G ++ AL AA+ H+++VK L+ +G DI++ Sbjct: 142 AAENGYYEVVTYLINKGCDPRSDYDY---ALRSAAEKGHIDVVKLLLEKGADISS 193 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 62,016,951 Number of Sequences: 219361 Number of extensions: 1180372 Number of successful extensions: 6172 Number of sequences better than 10.0: 462 Number of HSP's better than 10.0 without gapping: 4023 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5417 length of database: 80,573,946 effective HSP length: 106 effective length of database: 57,321,680 effective search space used: 4757699440 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
