>DCNL4_HUMAN (Q92564) DCN1-like protein 4 (Defective in cullin neddylation|
           protein 1-like protein 4) (DCUN1 domain-containing
           protein 4)
          Length = 292

 Score = 79.3 bits (194), Expect = 8e-15
 Identities = 43/124 (34%), Positives = 70/124 (56%)
 Frame = +3

Query: 213 ERIDQLFFTYADSSSSMIDPEGIETLCSHLEVPHTDVRILMLAWKMGCEKQGYFTLDEWR 392
           +R  + F+ YA  +  ++ PEG+E  C  + V   +V +L+LAWK+  +  GYFTL EW 
Sbjct: 104 KRCLEWFYEYA-GTDDVVGPEGMEKFCEDIGVEPENVVMLVLAWKLDAQNMGYFTLQEWL 162

Query: 393 TGMKALRADSISKLKKAFPELVQEVTRSSNFHDFYPYAFRYCLTEDKKKCIEIPVACELL 572
            GM +L+ D+  KL+     L   +  S+NF   Y YAF +   +D++  ++I  A  +L
Sbjct: 163 KGMTSLQCDTTEKLRNTLDYLRSFLNDSTNFKLIYRYAFDFAREKDQRS-LDINTAKCML 221

Query: 573 NLVL 584
            L+L
Sbjct: 222 GLLL 225

>DCNL4_MOUSE (Q8CCA0) DCN1-like protein 4 (Defective in cullin neddylation|
           protein 1-like protein 4) (DCUN1 domain-containing
           protein 4)
          Length = 292

 Score = 77.4 bits (189), Expect = 3e-14
 Identities = 42/124 (33%), Positives = 70/124 (56%)
 Frame = +3

Query: 213 ERIDQLFFTYADSSSSMIDPEGIETLCSHLEVPHTDVRILMLAWKMGCEKQGYFTLDEWR 392
           +R  + F+ YA +  + + PEG+E  C  + V   +V +L+LAWK+  +  GYFTL EW 
Sbjct: 104 KRCLEWFYEYAGTEDA-VGPEGMEKFCEDIGVEPENVVMLVLAWKLDAQNMGYFTLQEWL 162

Query: 393 TGMKALRADSISKLKKAFPELVQEVTRSSNFHDFYPYAFRYCLTEDKKKCIEIPVACELL 572
            GM +L+ D+  KL+     L   +  ++NF   Y YAF +   +D++  ++I  A  +L
Sbjct: 163 KGMTSLQCDTTEKLRTTLDYLRSLLNDTTNFKLIYRYAFDFAREKDQRS-LDINTAKCML 221

Query: 573 NLVL 584
            L+L
Sbjct: 222 GLLL 225

>DCNL4_BRARE (Q5RHX6) DCN1-like protein 4 (Defective in cullin neddylation|
           protein 1-like protein 4) (DCUN1 domain-containing
           protein 4)
          Length = 280

 Score = 76.3 bits (186), Expect = 7e-14
 Identities = 41/124 (33%), Positives = 70/124 (56%)
 Frame = +3

Query: 213 ERIDQLFFTYADSSSSMIDPEGIETLCSHLEVPHTDVRILMLAWKMGCEKQGYFTLDEWR 392
           +R  + F+ YA     ++ PEG+E  C  + V   +V +L+LAWK+  +  GYFTL EW 
Sbjct: 92  KRCLEWFYEYA-GCDDVVGPEGMEKFCEDIGVEPENVVMLVLAWKLDAQSMGYFTLQEWL 150

Query: 393 TGMKALRADSISKLKKAFPELVQEVTRSSNFHDFYPYAFRYCLTEDKKKCIEIPVACELL 572
            GM +L+ DS  KL+ +   L   +  +++F   Y YAF +   +D++  +++  A  +L
Sbjct: 151 KGMGSLQCDSTEKLRNSLDYLRSVLNDATSFKLIYRYAFDFAREKDQRS-LDLNTAKCML 209

Query: 573 NLVL 584
            L+L
Sbjct: 210 GLLL 213

>DCNL1_MOUSE (Q9QZ73) DCN1-like protein 1 (Defective in cullin neddylation|
           protein 1-like protein 1) (DCUN1 domain-containing
           protein 1) (Testis-specific protein 3)
          Length = 259

 Score = 74.3 bits (181), Expect = 3e-13
 Identities = 40/130 (30%), Positives = 68/130 (52%), Gaps = 1/130 (0%)
 Frame = +3

Query: 213 ERIDQLFFTYAD-SSSSMIDPEGIETLCSHLEVPHTDVRILMLAWKMGCEKQGYFTLDEW 389
           ++++QL+  Y D    + I  +GI+  C  L +    + +L++AWK     Q  F+  E+
Sbjct: 63  KKLEQLYTRYKDPQDENKIGIDGIQQFCDDLALDPASISVLIIAWKFRAATQCEFSKQEF 122

Query: 390 RTGMKALRADSISKLKKAFPELVQEVTRSSNFHDFYPYAFRYCLTEDKKKCIEIPVACEL 569
             GM  L  DSI KLK   P++ QE+     F DFY + F +     +K  +++ +A   
Sbjct: 123 MDGMTELGCDSIEKLKAQIPKMEQELKEPGRFKDFYQFTFNFAKNPGQKG-LDLEMAIAY 181

Query: 570 LNLVLSLQFR 599
            NLVL+ +F+
Sbjct: 182 WNLVLNGRFK 191

>DCNL1_HUMAN (Q96GG9) DCN1-like protein 1 (Defective in cullin neddylation|
           protein 1-like protein 1) (DCUN1 domain-containing
           protein 1) (Squamous cell carcinoma-related oncogene)
          Length = 259

 Score = 73.9 bits (180), Expect = 3e-13
 Identities = 40/130 (30%), Positives = 68/130 (52%), Gaps = 1/130 (0%)
 Frame = +3

Query: 213 ERIDQLFFTYAD-SSSSMIDPEGIETLCSHLEVPHTDVRILMLAWKMGCEKQGYFTLDEW 389
           ++++QL+  Y D    + I  +GI+  C  L +    + +L++AWK     Q  F+  E+
Sbjct: 63  KKLEQLYNRYKDPQDENKIGIDGIQQFCDDLALDPASISVLIIAWKFRAATQCEFSKQEF 122

Query: 390 RTGMKALRADSISKLKKAFPELVQEVTRSSNFHDFYPYAFRYCLTEDKKKCIEIPVACEL 569
             GM  L  DSI KLK   P++ QE+     F DFY + F +     +K  +++ +A   
Sbjct: 123 MDGMTELGCDSIEKLKAQIPKMEQELKEPGRFKDFYQFTFNFAKNPGQKG-LDLEMAIAY 181

Query: 570 LNLVLSLQFR 599
            NLVL+ +F+
Sbjct: 182 WNLVLNGRFK 191

>DCN1L_DROME (Q9VUQ8) DCN1-like protein (Defective in cullin neddylation protein|
           1-like protein)
          Length = 288

 Score = 73.6 bits (179), Expect = 4e-13
 Identities = 46/130 (35%), Positives = 69/130 (53%), Gaps = 1/130 (0%)
 Frame = +3

Query: 213 ERIDQLFFTYADSSSSM-IDPEGIETLCSHLEVPHTDVRILMLAWKMGCEKQGYFTLDEW 389
           +RI+QLF  Y D S  + I  +G+      L++      +L++AWK   E Q  F+ DE+
Sbjct: 59  KRIEQLFMRYRDPSDPLKIGSQGVIHFLEDLDLKPDSKLVLIIAWKFHAEVQCEFSRDEF 118

Query: 390 RTGMKALRADSISKLKKAFPELVQEVTRSSNFHDFYPYAFRYCLTEDKKKCIEIPVACEL 569
             GM  L  DSI KLK   P L QE+  +  F DFY + F Y   +  +K I++ +A   
Sbjct: 119 INGMCDLGIDSIDKLKTKLPILEQELNDAGKFKDFYHFTFNYA-KDPGQKGIDLEMAIAY 177

Query: 570 LNLVLSLQFR 599
             +VLS +F+
Sbjct: 178 WCIVLSGRFK 187

>DCNL1_CHICK (Q5ZKU1) DCN1-like protein 1 (Defective in cullin neddylation|
           protein 1-like protein 1) (DCUN1 domain-containing
           protein 1)
          Length = 259

 Score = 72.4 bits (176), Expect = 1e-12
 Identities = 40/130 (30%), Positives = 68/130 (52%), Gaps = 1/130 (0%)
 Frame = +3

Query: 213 ERIDQLFFTYAD-SSSSMIDPEGIETLCSHLEVPHTDVRILMLAWKMGCEKQGYFTLDEW 389
           ++++QL+  Y D    + I  +GI+  C  L +    + +L++AWK     Q  F+  E+
Sbjct: 63  KKLEQLYNRYKDPQDENKIGIDGIQQFCDDLALDPASITVLIIAWKFRAATQCEFSKLEF 122

Query: 390 RTGMKALRADSISKLKKAFPELVQEVTRSSNFHDFYPYAFRYCLTEDKKKCIEIPVACEL 569
             GM  L  DSI KLK   P++ QE+     F DFY + F +     +K  +++ +A   
Sbjct: 123 MDGMTELGCDSIEKLKAQIPKMEQELKEPGRFKDFYQFTFNFAKNPGQKG-LDLEMAIAY 181

Query: 570 LNLVLSLQFR 599
            NLVL+ +F+
Sbjct: 182 WNLVLNGRFK 191

>DCNL2_HUMAN (Q6PH85) DCN1-like protein 2 (Defective in cullin neddylation|
           protein 2-like protein 2) (DCUN1 domain-containing
           protein 2)
          Length = 259

 Score = 70.5 bits (171), Expect = 4e-12
 Identities = 39/130 (30%), Positives = 68/130 (52%), Gaps = 1/130 (0%)
 Frame = +3

Query: 213 ERIDQLFFTYAD-SSSSMIDPEGIETLCSHLEVPHTDVRILMLAWKMGCEKQGYFTLDEW 389
           +++++L+  Y D    + I  +GI+  C  L +    + +L++AWK     Q  F+  E+
Sbjct: 63  KKLERLYGRYKDPQDENKIGVDGIQQFCDDLSLDPASISVLVIAWKFRAATQCEFSRKEF 122

Query: 390 RTGMKALRADSISKLKKAFPELVQEVTRSSNFHDFYPYAFRYCLTEDKKKCIEIPVACEL 569
             GM  L  DS+ KLK   P L QE+  ++ F DFY + F +     +K  +++ +A   
Sbjct: 123 LDGMTELGCDSMEKLKALLPRLEQELKDTAKFKDFYQFTFTFAKNPGQKG-LDLEMAVAY 181

Query: 570 LNLVLSLQFR 599
             LVLS +F+
Sbjct: 182 WKLVLSGRFK 191

>DCN1_CAEEL (Q9U3C8) Defective in cullin neddylation protein 1|
          Length = 295

 Score = 68.2 bits (165), Expect = 2e-11
 Identities = 37/104 (35%), Positives = 57/104 (54%), Gaps = 5/104 (4%)
 Frame = +3

Query: 219 IDQLFFTYADSSSSM----IDPEGIETLCSHLEVPHTDVRILMLAWKMGCEKQGYFTLDE 386
           I++LF  Y D    +    + P GI  L + L    TD R+L+LAWK   + Q  F+LDE
Sbjct: 65  IERLFNQYVDPKDKVGEKRMGPHGINRLLTDLGYEATDRRVLVLAWKFTAQTQCEFSLDE 124

Query: 387 WRTGMKALRADSISKLKKAFPELVQEV-TRSSNFHDFYPYAFRY 515
           W  GM AL+AD++  L++    +   + +  + FH+ Y +AF Y
Sbjct: 125 WVKGMTALQADTVQNLRQRIDSINSGLESDKAKFHELYLFAFNY 168

>DCNL2_MOUSE (Q8BZJ7) DCN1-like protein 2 (Defective in cullin neddylation|
           protein 2-like protein 2) (DCUN1 domain-containing
           protein 2)
          Length = 258

 Score = 66.6 bits (161), Expect = 5e-11
 Identities = 38/130 (29%), Positives = 65/130 (50%), Gaps = 1/130 (0%)
 Frame = +3

Query: 213 ERIDQLFFTYAD-SSSSMIDPEGIETLCSHLEVPHTDVRILMLAWKMGCEKQGYFTLDEW 389
           ++++QL+  Y D    + I  +GI+  C  L +    + +L++AWK     Q  F+  E+
Sbjct: 63  KKLEQLYSRYKDPQDENKIGIDGIQQFCDDLSLDPASISVLVIAWKFRAATQCEFSKKEF 122

Query: 390 RTGMKALRADSISKLKKAFPELVQEVTRSSNFHDFYPYAFRYCLTEDKKKCIEIPVACEL 569
             GM  L  DS  +LK   P L QE+   + F D Y + F +     +K  +++ +A   
Sbjct: 123 VDGMTELGCDSTERLKALLPRLEQELKDPAKFKDLYQFTFTFAKNPGQKG-LDLEMAVAY 181

Query: 570 LNLVLSLQFR 599
             LVLS +F+
Sbjct: 182 WKLVLSGRFK 191

>DCN1_CAEBR (Q60YT5) Defective in cullin neddylation protein 1|
          Length = 292

 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 30/80 (37%), Positives = 40/80 (50%), Gaps = 3/80 (3%)
 Frame = +3

Query: 225 QLFFTYADSSSSM---IDPEGIETLCSHLEVPHTDVRILMLAWKMGCEKQGYFTLDEWRT 395
           QLF  Y D    +   I P G++ L   L     D R+L+LAW    E Q  F+L E+  
Sbjct: 66  QLFTQYVDKRDGLGERIGPHGMQRLLIDLGYEPIDRRVLILAWVFKAETQCEFSLQEFTN 125

Query: 396 GMKALRADSISKLKKAFPEL 455
           GM +L+ DSI  LK+    L
Sbjct: 126 GMASLQVDSIQGLKQKIDAL 145

>P_HUMAN (Q04671) P protein (Melanocyte-specific transporter protein)|
           (Pink-eyed dilution protein homolog)
          Length = 838

 Score = 31.6 bits (70), Expect = 1.9
 Identities = 16/54 (29%), Positives = 29/54 (53%), Gaps = 2/54 (3%)
 Frame = -1

Query: 466 TSWTSSGKAFFSLLMLSARRAFIPVLHSSRVK*PCFSQ--PIFHANIRIRTSVC 311
           +SW  +G+ F S L      + +P + SSR K  CF++  P+   +++ + S C
Sbjct: 59  SSWAPAGQEFASFLTKGRSHSSLPQMSSSRSKDSCFTENTPLLRNSLQEKGSRC 112

>VE2_HPV38 (Q80910) Regulatory protein E2|
          Length = 441

 Score = 30.0 bits (66), Expect = 5.6
 Identities = 21/49 (42%), Positives = 26/49 (53%), Gaps = 1/49 (2%)
 Frame = +3

Query: 3   TRTLNRDSREDETRRDNSATARRGEVG-TRDEREGGGDKKPRGRATMRR 146
           +R+ NR  R+  TRR +S   R   V  TR  R GGGD + RG  T  R
Sbjct: 271 SRSTNRGGRD--TRRSSS---RGSSVSPTRGRRRGGGDSRRRGPVTRSR 314

>MOG1_CAEEL (P34498) Probable pre-mRNA-splicing factor ATP-dependent RNA|
           helicase mog-1 (EC 3.6.1.-) (Sex determination protein
           mog-1) (Masculinization of germ line protein 1)
          Length = 1131

 Score = 30.0 bits (66), Expect = 5.6
 Identities = 14/40 (35%), Positives = 21/40 (52%)
 Frame = +3

Query: 6   RTLNRDSREDETRRDNSATARRGEVGTRDEREGGGDKKPR 125
           R +   SR+D+ RRD   + RR     R  ++  GD+ PR
Sbjct: 88  RGMKYKSRDDDRRRDRDRSERREPSSRRGWKDRSGDQTPR 127

>SYK_THEVO (Q979B8) Lysyl-tRNA synthetase (EC 6.1.1.6) (Lysine--tRNA ligase)|
           (LysRS)
          Length = 503

 Score = 29.3 bits (64), Expect = 9.5
 Identities = 22/96 (22%), Positives = 40/96 (41%), Gaps = 1/96 (1%)
 Frame = +3

Query: 219 IDQLFFTYADSSSSMI-DPEGIETLCSHLEVPHTDVRILMLAWKMGCEKQGYFTLDEWRT 395
           +DQ +  Y       I  P+G+     H   P  +V       K G   +   T D +  
Sbjct: 71  LDQSYSKYVGFPLKNIPSPDGVGVYSDHFLNPFIEVMR-----KTGIPARVIKTSDLYGN 125

Query: 396 GMKALRADSISKLKKAFPELVQEVTRSSNFHDFYPY 503
           G+ A   D++ + +    ++++++T      DFYPY
Sbjct: 126 GILADAIDTVMERRSEIKDILEKITGRMIEGDFYPY 161


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 72,683,202
Number of Sequences: 219361
Number of extensions: 1326281
Number of successful extensions: 3624
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 3466
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3621
length of database: 80,573,946
effective HSP length: 107
effective length of database: 57,102,319
effective search space used: 5481822624
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)