>RPC7_HUMAN (O15318) DNA-directed RNA polymerase III 32 kDa polypeptide (EC|
           2.7.7.6) (RNA polymerase III C32 subunit)
          Length = 233

 Score = 33.1 bits (74), Expect = 0.34
 Identities = 23/61 (37%), Positives = 35/61 (57%), Gaps = 3/61 (4%)
 Frame = +1

Query: 277 LADVIDVMKKEVEEKKRG-GDRG--ENKEDAGAGDKSNWMSTAQLWTGDSVRGDDASEKQ 447
           L +  DV+KK VE +KRG G++   EN+E  G+ +KS          GD    DDA+E++
Sbjct: 135 LTNTEDVLKKMVELEKRGDGEKSDEENEEKEGSKEKSK--------EGDDDDDDDAAEQE 186

Query: 448 D 450
           +
Sbjct: 187 E 187

>MUTS2_AQUAE (O67287) MutS2 protein|
          Length = 762

 Score = 32.3 bits (72), Expect = 0.58
 Identities = 23/72 (31%), Positives = 38/72 (52%), Gaps = 3/72 (4%)
 Frame = +1

Query: 148 AAKSLGRAREAPAAAMD---DCIRRLEEEKSKIEVFRRELPLCARLLADVIDVMKKEVEE 318
           A + +G   E    AM+   D +++ EEE  K+E  R+EL    +   + ++ ++KE EE
Sbjct: 502 AKRHVGEFGEQYIKAMEKLSDYVKKYEEEFRKLEELRKEL----QKEKEEVEKLRKEYEE 557

Query: 319 KKRGGDRGENKE 354
            KR G +   KE
Sbjct: 558 AKRKGWKEAYKE 569

>RENT2_HUMAN (Q9HAU5) Regulator of nonsense transcripts 2 (Nonsense mRNA|
           reducing factor 2) (Up-frameshift suppressor 2 homolog)
           (hUpf2)
          Length = 1272

 Score = 31.2 bits (69), Expect = 1.3
 Identities = 26/90 (28%), Positives = 45/90 (50%)
 Frame = +1

Query: 133 DLKMFAAKSLGRAREAPAAAMDDCIRRLEEEKSKIEVFRRELPLCARLLADVIDVMKKEV 312
           D+K+ A K + +A E       D  +RLE++K K E   R+     ++ A+  +  KKE 
Sbjct: 40  DIKLTAKKEVSKAPE-------DKKKRLEDDKRKKEDKERKKKDEEKVKAEE-ESKKKEE 91

Query: 313 EEKKRGGDRGENKEDAGAGDKSNWMSTAQL 402
           EEKK+  +    K++  A  +    + AQ+
Sbjct: 92  EEKKKHQEEERKKQEEQAKRQQEEEAAAQM 121

>PFDA_HALMA (Q5UY26) Prefoldin alpha subunit (GimC alpha subunit)|
          Length = 154

 Score = 30.8 bits (68), Expect = 1.7
 Identities = 20/80 (25%), Positives = 34/80 (42%)
 Frame = +1

Query: 19  TFSCNKSVKIPFGAPVRCKPNPMGLDVGEIGMGADLSLDLKMFAAKSLGRAREAPAAAMD 198
           T     +V++P G     +     +D   + +G   S + +   A S     E     +D
Sbjct: 54  TLDSGSTVQVPLGGDAYIRATIEDIDEVVVSLGGGYSAEREQDGAVS---TLETKKETLD 110

Query: 199 DCIRRLEEEKSKIEVFRREL 258
           D I  L+EEK+++E    EL
Sbjct: 111 DHISDLQEEKAEVETEMEEL 130

>IF2_VIBPA (Q87M02) Translation initiation factor IF-2|
          Length = 905

 Score = 30.4 bits (67), Expect = 2.2
 Identities = 25/95 (26%), Positives = 43/95 (45%), Gaps = 2/95 (2%)
 Frame = +1

Query: 175 EAPAAAMDDCIRRLEEEKSKI--EVFRRELPLCARLLADVIDVMKKEVEEKKRGGDRGEN 348
           EA   A +   R  EE   ++  E  +RE    A+  A+  D +K+E EEK +     + 
Sbjct: 106 EAKREAEEVAKREAEEAAKRVAEETAKREAEEAAKREAE--DAVKREAEEKAKREAEEKA 163

Query: 349 KEDAGAGDKSNWMSTAQLWTGDSVRGDDASEKQDE 453
           K DA    + N    A+    + ++ + A ++ DE
Sbjct: 164 KRDADTNAQRNAEEKAKRDAEEKIKQEAARKEADE 198

>GOGA4_HUMAN (Q13439) Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa|
           golgin) (Golgin-245) (Protein 72.1)
          Length = 2230

 Score = 30.4 bits (67), Expect = 2.2
 Identities = 20/65 (30%), Positives = 36/65 (55%), Gaps = 1/65 (1%)
 Frame = +1

Query: 130 LDLKMFAAKSLGRAREAPAAAMDDCIRRLEEEKSKIEV-FRRELPLCARLLADVIDVMKK 306
           L+  +  A+    AR    A MD+ I+ +E+   +  +  ++EL   +R+  +V+DVMKK
Sbjct: 416 LEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQEL---SRVKQEVVDVMKK 472

Query: 307 EVEEK 321
             EE+
Sbjct: 473 SSEEQ 477

>PFDA_AQUAE (O66961) Putative prefoldin alpha subunit|
          Length = 149

 Score = 30.4 bits (67), Expect = 2.2
 Identities = 24/106 (22%), Positives = 45/106 (42%)
 Frame = +1

Query: 34  KSVKIPFGAPVRCKPNPMGLDVGEIGMGADLSLDLKMFAAKSLGRAREAPAAAMDDCIRR 213
           K V IP GA  + K    G+D   + +G  +S                    + D+ + R
Sbjct: 64  KEVLIPVGATAQIKAKSEGVDEVIMSIGTGIS-----------------AVMSYDEAVDR 106

Query: 214 LEEEKSKIEVFRRELPLCARLLADVIDVMKKEVEEKKRGGDRGENK 351
           + +E + +E  RR L      +AD+ + +++ +EE ++ G     K
Sbjct: 107 IRKEIAALEALRRAL---EEAIADLYNKIEELLEEVRKVGQEEAKK 149

>FLNB_MOUSE (Q80X90) Filamin-B (FLN-B) (Beta-filamin) (Actin-binding-like|
            protein) (ABP-280-like protein)
          Length = 2602

 Score = 30.0 bits (66), Expect = 2.9
 Identities = 15/48 (31%), Positives = 23/48 (47%)
 Frame = +1

Query: 61   PVRCKPNPMGLDVGEIGMGADLSLDLKMFAAKSLGRAREAPAAAMDDC 204
            P + K +  GL+ G +G  A+ ++D K      LG   E P  A  +C
Sbjct: 1040 PTKVKAHGPGLEGGLVGKPAEFTIDTKGAGTGGLGLTVEGPCEAKIEC 1087

>Y096_MYCGE (P47342) Hypothetical protein MG096|
          Length = 650

 Score = 29.6 bits (65), Expect = 3.8
 Identities = 25/95 (26%), Positives = 44/95 (46%)
 Frame = +1

Query: 166 RAREAPAAAMDDCIRRLEEEKSKIEVFRRELPLCARLLADVIDVMKKEVEEKKRGGDRGE 345
           + REA   A ++  RRLEEE+      +R+L    R  A+     K++ EE KR  ++  
Sbjct: 330 KEREAAKKAYEEEQRRLEEER------KRQLEELRRREAE----EKRKAEEAKRNQEKAR 379

Query: 346 NKEDAGAGDKSNWMSTAQLWTGDSVRGDDASEKQD 450
            + +A     +++      W     +G D ++K D
Sbjct: 380 REREAYEKSFNSFKDFKFYWL---TKGKDVTKKAD 411

>THYX_PYRKO (Q5JI17) Thymidylate synthase thyX (EC 2.1.1.148) (TS) (TSase)|
          Length = 245

 Score = 29.6 bits (65), Expect = 3.8
 Identities = 13/29 (44%), Positives = 22/29 (75%)
 Frame = +1

Query: 274 LLADVIDVMKKEVEEKKRGGDRGENKEDA 360
           LLA+  ++MKK +E  K+  +RG+++EDA
Sbjct: 120 LLAEWKELMKKSIELYKKSVERGQHQEDA 148

>DEP1_YEAST (P31385) Protein DEP1|
          Length = 420

 Score = 29.6 bits (65), Expect = 3.8
 Identities = 22/80 (27%), Positives = 36/80 (45%), Gaps = 4/80 (5%)
 Frame = +1

Query: 154 KSLGRAREAPAAAMDDCIRRL----EEEKSKIEVFRRELPLCARLLADVIDVMKKEVEEK 321
           +SL R  E    A+D+  +       E++SK E   +EL        + ID  +K  + +
Sbjct: 85  ESLKRPHEDEKEAIDEAKKMKVPGENEDESKEEEKSQELE-------EAIDSKEKSTDAR 137

Query: 322 KRGGDRGENKEDAGAGDKSN 381
              GD G+N+E+    D  N
Sbjct: 138 DEQGDEGDNEEENNEEDNEN 157

>YD186_YEAST (P48568) Hypothetical 32.2 kDa protein in PPH22-VMA1 intergenic|
           region
          Length = 277

 Score = 29.6 bits (65), Expect = 3.8
 Identities = 15/31 (48%), Positives = 18/31 (58%)
 Frame = +1

Query: 40  VKIPFGAPVRCKPNPMGLDVGEIGMGADLSL 132
           V  P+ AP R K NP    V EIG G +LS+
Sbjct: 183 VLFPYEAPTRTKQNPAERKVIEIGDGEELSI 213

>PP220_ASFB7 (Q08358) Polyprotein pp220 (220 kDa polyprotein) [Contains: p34;|
           p14; p37; p150]
          Length = 2474

 Score = 29.6 bits (65), Expect = 3.8
 Identities = 25/84 (29%), Positives = 41/84 (48%), Gaps = 3/84 (3%)
 Frame = +1

Query: 124 LSLDLKMFAAKSLGRAREAPAAAMDD--CIRRLEEEKSKIEV-FRRELPLCARLLADVID 294
           ++LDL +    +   ARE     +     ++ + EE+SKI+  F+     C+RLL  +ID
Sbjct: 440 IALDLSLIGFYTNAAAREERETFLTQFMLVKNVLEEQSKIDPNFKNLYDSCSRLL-QIID 498

Query: 295 VMKKEVEEKKRGGDRGENKEDAGA 366
                V++K  GG+  E     GA
Sbjct: 499 FYTDIVQKKYGGGEDCECTRVGGA 522

>FLNB_HUMAN (O75369) Filamin-B (FLN-B) (Beta-filamin) (Actin-binding-like|
            protein) (Thyroid autoantigen) (Truncated actin-binding
            protein) (Truncated ABP) (ABP-280 homolog) (ABP-278)
            (Filamin 3) (Filamin homolog 1) (Fh1)
          Length = 2602

 Score = 29.3 bits (64), Expect = 4.9
 Identities = 15/48 (31%), Positives = 23/48 (47%)
 Frame = +1

Query: 61   PVRCKPNPMGLDVGEIGMGADLSLDLKMFAAKSLGRAREAPAAAMDDC 204
            P + K +  GL+ G +G  A+ ++D K      LG   E P  A  +C
Sbjct: 1040 PSKVKAHGPGLEGGLVGKPAEFTIDTKGAGTGGLGLTVEGPCEAKIEC 1087

>SPT6H_CAEEL (P34703) Suppressor of Ty 6 homolog (Abnormal embryogenesis protein|
           5)
          Length = 1521

 Score = 29.3 bits (64), Expect = 4.9
 Identities = 14/46 (30%), Positives = 25/46 (54%), Gaps = 1/46 (2%)
 Frame = +1

Query: 322 KRGGDRGENKEDAGAGDKSNWMSTAQLWTGDSVRGD-DASEKQDER 456
           +RG D G+ ++D G GD+  + S ++    D +  D DA  +  +R
Sbjct: 140 ERGSDDGDRRKDRGRGDRGGYGSESERSEDDFIEDDGDAPRRHRKR 185

>RRP3_YEAST (P38712) ATP-dependent rRNA helicase RRP3 (EC 3.6.1.-) (Ribosomal|
           RNA-processing protein RRP3)
          Length = 501

 Score = 29.3 bits (64), Expect = 4.9
 Identities = 13/38 (34%), Positives = 22/38 (57%)
 Frame = +1

Query: 262 LCARLLADVIDVMKKEVEEKKRGGDRGENKEDAGAGDK 375
           L  ++ A  ++  KK +E +K GG   +++EDA A  K
Sbjct: 19  LAEKIRAKALENQKKLIEAEKEGGSESDSEEDATAEKK 56

>RNR_UREPA (Q9PR88) Ribonuclease R (EC 3.1.-.-) (RNase R) (VacB protein|
           homolog)
          Length = 721

 Score = 29.3 bits (64), Expect = 4.9
 Identities = 21/90 (23%), Positives = 41/90 (45%), Gaps = 4/90 (4%)
 Frame = +1

Query: 130 LDLKMFAAKSLGRAREAPAAAMDDCIRRLEEEK--SKIEVFRRELPLCARL--LADVIDV 297
           +D+K++  K+     E    A ++ +    EE     ++ F  E+P   R+     +I++
Sbjct: 434 IDIKIYERKTAQMMVEDFMIAANEAVTMFAEEHMDKTLKEFNLEMPFIYRVHDKPSIINL 493

Query: 298 MKKEVEEKKRGGDRGENKEDAGAGDKSNWM 387
            K E+E KK   +   + E+      SNW+
Sbjct: 494 QKFEIEAKKLSFNISHDFENIQPNTISNWL 523

>EGFL7_HUMAN (Q9UHF1) EGF-like domain-containing protein 7 precursor (Multiple|
           EGF-like domain protein 7) (Multiple epidermal growth
           factor-like domain protein 7) (Vascular endothelial
           statin) (VE-statin) (NOTCH4-like protein) (ZNEU1)
          Length = 273

 Score = 29.3 bits (64), Expect = 4.9
 Identities = 11/27 (40%), Positives = 17/27 (62%)
 Frame = +1

Query: 16  HTFSCNKSVKIPFGAPVRCKPNPMGLD 96
           H+ S + ++ +P G P R  PNP G+D
Sbjct: 167 HSLSADGTLCVPKGGPPRVAPNPTGVD 193

>HS90A_CHICK (P11501) Heat shock protein HSP 90-alpha|
          Length = 728

 Score = 28.9 bits (63), Expect = 6.4
 Identities = 22/79 (27%), Positives = 31/79 (39%)
 Frame = +1

Query: 172 REAPAAAMDDCIRRLEEEKSKIEVFRRELPLCARLLADVIDVMKKEVEEKKRGGDRGENK 351
           +E      DD     EEEK + E    + P       ++ DV   E EEKK G  + + K
Sbjct: 223 KERDKEVSDDEAEEKEEEKEEKEEKTEDKP-------EIEDVGSDEEEEKKDGDKKKKKK 275

Query: 352 EDAGAGDKSNWMSTAQLWT 408
                 D+     T  +WT
Sbjct: 276 IKEKYIDEEELNKTKPIWT 294

>CNGB1_BOVIN (Q28181) 240 kDa protein of rod photoreceptor CNG-channel|
           [Contains: Glutamic acid-rich protein (GARP);
           Cyclic-nucleotide-gated cation channel 4 (CNG channel 4)
           (CNG-4) (Cyclic nucleotide-gated cation channel
           modulatory subunit)]
          Length = 1394

 Score = 28.9 bits (63), Expect = 6.4
 Identities = 23/84 (27%), Positives = 37/84 (44%), Gaps = 5/84 (5%)
 Frame = +1

Query: 217 EEEKSKI-EVFRRELPLCARLLADVIDVMKKEVEEKKRGGDR----GENKEDAGAGDKSN 381
           +EEK K+ E   RELP       D  +  +   EE++ G ++    GE KE+    +K  
Sbjct: 336 DEEKGKVVEQTPRELPRIQEEKEDEEEEKEDGEEEEEEGREKEEEEGEEKEEEEGREKEE 395

Query: 382 WMSTAQLWTGDSVRGDDASEKQDE 453
                +   G     ++  EK+DE
Sbjct: 396 EEGEKKEEEGREKEEEEGGEKEDE 419

>LMNA_CHICK (P13648) Lamin-A|
          Length = 657

 Score = 28.9 bits (63), Expect = 6.4
 Identities = 18/74 (24%), Positives = 35/74 (47%)
 Frame = +1

Query: 133 DLKMFAAKSLGRAREAPAAAMDDCIRRLEEEKSKIEVFRRELPLCARLLADVIDVMKKEV 312
           DL+   AK  G   EA     D+ +RR++ E ++++  + EL     + ++ +   K+  
Sbjct: 163 DLRAQVAKLEGALSEAKKQLQDEMLRRVDAE-NRLQTLKEELEFQKNIYSEELRETKRRH 221

Query: 313 EEKKRGGDRGENKE 354
           E +    D G  +E
Sbjct: 222 ETRLVEIDNGRQQE 235

>MYH14_HUMAN (Q7Z406) Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle|
            myosin heavy chain IIc) (NMHC II-C)
          Length = 1995

 Score = 28.9 bits (63), Expect = 6.4
 Identities = 16/65 (24%), Positives = 30/65 (46%)
 Frame = +1

Query: 160  LGRAREAPAAAMDDCIRRLEEEKSKIEVFRRELPLCARLLADVIDVMKKEVEEKKRGGDR 339
            L R R      +DD    LE+++  +    ++     +LLA+    + + VEE++R    
Sbjct: 1435 LERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAE 1494

Query: 340  GENKE 354
            G  +E
Sbjct: 1495 GRERE 1499

>MNN4_YEAST (P36044) Protein MNN4|
          Length = 1178

 Score = 28.5 bits (62), Expect = 8.4
 Identities = 18/79 (22%), Positives = 37/79 (46%)
 Frame = +1

Query: 217  EEEKSKIEVFRRELPLCARLLADVIDVMKKEVEEKKRGGDRGENKEDAGAGDKSNWMSTA 396
            EE+K K E  +++     +   +  +  KKE EEKK+  +  + K++     K       
Sbjct: 1048 EEKKKKEEEEKKKKEEEEKKKKEEEEKKKKEEEEKKKKEEEEKKKQEEEEKKKKEEEEKK 1107

Query: 397  QLWTGDSVRGDDASEKQDE 453
            +   G+ ++ +D   K++E
Sbjct: 1108 KQEEGEKMKNEDEENKKNE 1126

>IMUA_CAUCR (Q9A3J1) Protein imuA|
          Length = 244

 Score = 28.5 bits (62), Expect = 8.4
 Identities = 15/39 (38%), Positives = 21/39 (53%)
 Frame = -2

Query: 182 GASLARPRLLAANIFKSRLKSAPMPISPTSRPIGLGLQR 66
           G +  +PRL++ +   SR + AP P  P    IGLG  R
Sbjct: 155 GRAGGKPRLVSGSASFSRWRIAPAPSGPPPDDIGLGPPR 193

>ZCHC6_MOUSE (Q5BLK4) Zinc finger CCHC domain-containing protein 6|
          Length = 1491

 Score = 28.5 bits (62), Expect = 8.4
 Identities = 19/76 (25%), Positives = 33/76 (43%)
 Frame = +1

Query: 130 LDLKMFAAKSLGRAREAPAAAMDDCIRRLEEEKSKIEVFRRELPLCARLLADVIDVMKKE 309
           +D  + + K L   ++A      DCI RL+         +    LC  L+ D I    K 
Sbjct: 204 IDESVLSTKELLGLQQAEERLKRDCIDRLKRRPRNCPTAKYTCKLCDALI-DSIPFAHKH 262

Query: 310 VEEKKRGGDRGENKED 357
           ++EK+   +  E +E+
Sbjct: 263 IKEKRHKKNLKEKQEE 278

>FAM9A_HUMAN (Q8IZU1) Protein FAM9A|
          Length = 332

 Score = 28.5 bits (62), Expect = 8.4
 Identities = 22/77 (28%), Positives = 34/77 (44%)
 Frame = +1

Query: 148 AAKSLGRAREAPAAAMDDCIRRLEEEKSKIEVFRRELPLCARLLADVIDVMKKEVEEKKR 327
           AA     A EA AAA +  +   EEE+ K E   +E               ++E  E++ 
Sbjct: 199 AAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKE--------------EEEEEGEEEG 244

Query: 328 GGDRGENKEDAGAGDKS 378
           GG+ GE     G G+++
Sbjct: 245 GGEEGEEGGGGGEGEET 261

>AFAD_RAT (O35889) Afadin (Af-6 protein)|
          Length = 1829

 Score = 28.5 bits (62), Expect = 8.4
 Identities = 14/56 (25%), Positives = 24/56 (42%)
 Frame = +1

Query: 286  VIDVMKKEVEEKKRGGDRGENKEDAGAGDKSNWMSTAQLWTGDSVRGDDASEKQDE 453
            ++D++ KE+ E +  GDR   + D        W    +L        DD  E+ D+
Sbjct: 1537 IVDMLSKEIHELQNKGDRTAEESDRLRKLMLEWQFQKRLQESKQKDEDDDEEEDDD 1592

>CPCE_ANASP (P07125) Phycocyanobilin lyase alpha subunit (EC 4.-.-.-)|
           (Phycocyanin operon protein cpcE)
          Length = 276

 Score = 28.5 bits (62), Expect = 8.4
 Identities = 15/38 (39%), Positives = 23/38 (60%)
 Frame = +1

Query: 130 LDLKMFAAKSLGRAREAPAAAMDDCIRRLEEEKSKIEV 243
           L L+ +AA  LG+ R   +AA+D  I  LE+E  + E+
Sbjct: 31  LSLRYYAAWWLGKYRVKESAAVDALIAALEDEADRTEL 68


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.314    0.133    0.390 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 51,679,479
Number of Sequences: 219361
Number of extensions: 941571
Number of successful extensions: 2932
Number of sequences better than 10.0: 28
Number of HSP's better than 10.0 without gapping: 2757
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2918
length of database: 80,573,946
effective HSP length: 102
effective length of database: 58,199,124
effective search space used: 2851757076
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)