Clone Name | bart48a05 |
---|---|
Clone Library Name | barley_pub |
>LAP1_CAEEL (O61967) Protein lap1 (Protein lethal-413)| Length = 699 Score = 102 bits (255), Expect = 6e-22 Identities = 67/185 (36%), Positives = 98/185 (52%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQL 192 L ++ +LDV N+L LP IG L++L LN++ N + LP T++ C+ L LN + N Sbjct: 58 LRHLRILDVSDNELAVLPAEIGNLTQLIELNLNRNSIAKLPDTMQNCKLLTTLNLSSNPF 117 Query: 193 TRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXX 372 TRLP+T+ E S+ LS+N LT LP + +T LR L+AR N +R Sbjct: 118 TRLPETI-CECSSITILSLNETSLTLLPSNIGSLTNLRVLEARDNLLRTIPLSIVELRKL 176 Query: 373 XXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPLIC 552 QN L LP +G LTSLRE + NS++ LPDS+ L++ N +I Sbjct: 177 EELDLGQN--ELEALPAEIGKLTSLREFYVDINSLTSLPDSISGCRMLDQLDVSENQIIR 234 Query: 553 PPMDI 567 P ++ Sbjct: 235 LPENL 239 Score = 91.7 bits (226), Expect = 1e-18 Identities = 63/188 (33%), Positives = 95/188 (50%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 I L + LD+ N+L++LP IG L+ LR V N L SLP +I CR L++L+ + Sbjct: 170 IVELRKLEELDLGQNELEALPAEIGKLTSLREFYVDINSLTSLPDSISGCRMLDQLDVSE 229 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXX 363 NQ+ RLP+ LG + +L L+++ N++ LP S + L+ L A N + Sbjct: 230 NQIIRLPENLG-RMPNLTDLNISINEIIELPSSFGELKRLQMLKADRNSLHNLTSEIGKC 288 Query: 364 XXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNP 543 QN FL +LP +G L L L++ N++S +PD++G L S N Sbjct: 289 QSLTELYLGQN--FLTDLPDTIGDLRQLTTLNVDCNNLSDIPDTIGNCKSLTVLSLRQNI 346 Query: 544 LICPPMDI 567 L PM I Sbjct: 347 LTELPMTI 354 Score = 87.8 bits (216), Expect = 2e-17 Identities = 65/181 (35%), Positives = 86/181 (47%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 I ++ +L + L LP++IG L+ LRVL NLL+++P +I E R LEEL+ Sbjct: 124 ICECSSITILSLNETSLTLLPSNIGSLTNLRVLEARDNLLRTIPLSIVELRKLEELDLGQ 183 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXX 363 N+L LP +G +L SLR V+ N LTSLP S S L LD N I Sbjct: 184 NELEALPAEIG-KLTSLREFYVDINSLTSLPDSISGCRMLDQLDVSENQI---------- 232 Query: 364 XXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNP 543 LP LG + +L +L+IS N I LP S G L +L A N Sbjct: 233 ---------------IRLPENLGRMPNLTDLNISINEIIELPSSFGELKRLQMLKADRNS 277 Query: 544 L 546 L Sbjct: 278 L 278 Score = 75.1 bits (183), Expect = 1e-13 Identities = 52/171 (30%), Positives = 84/171 (49%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 + R+ N+ L++ N++ LP+S G L +L++L N L +L + I +C++L EL Sbjct: 239 LGRMPNLTDLNISINEIIELPSSFGELKRLQMLKADRNSLHNLTSEIGKCQSLTELYLGQ 298 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXX 363 N LT LPDT+G +L L L+V+ N L+ +P + + +L L R N Sbjct: 299 NFLTDLPDTIG-DLRQLTTLNVDCNNLSDIPDTIGNCKSLTVLSLRQN------------ 345 Query: 364 XXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKL 516 L ELP +G +L LD++ N + LP ++ L KL Sbjct: 346 -------------ILTELPMTIGKCENLTVLDVASNKLPHLPFTVKVLYKL 383 Score = 63.9 bits (154), Expect = 3e-10 Identities = 41/103 (39%), Positives = 58/103 (56%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 I + ++ L + N L LP++IG L +L LNV N L +P TI C++L L+ Sbjct: 285 IGKCQSLTELYLGQNFLTDLPDTIGDLRQLTTLNVDCNNLSDIPDTIGNCKSLTVLSLRQ 344 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRAL 312 N LT LP T+G + +L L V SNKL LPF+ + L+AL Sbjct: 345 NILTELPMTIG-KCENLTVLDVASNKLPHLPFTVKVLYKLQAL 386 Score = 61.2 bits (147), Expect = 2e-09 Identities = 50/167 (29%), Positives = 77/167 (46%) Frame = +1 Query: 73 IGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDTLGFELHSLRRLSVN 252 + C ++ ++ S + LQ++P+ I R LE+LN N + L L F L LR L V+ Sbjct: 9 MACQRQVDSIDRSQSNLQAIPSDIFRFRKLEDLNLTMNNIKELDHRL-FSLRHLRILDVS 67 Query: 253 SNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHFLRELPYGLG 432 N+L LP ++T L L+ N I S N F R LP + Sbjct: 68 DNELAVLPAEIGNLTQLIELNLNRNSIAKLPDTMQNCKLLTTLNLSSN-PFTR-LPETIC 125 Query: 433 LLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPLICPPMDIVE 573 +S+ L ++ S+++LP ++G L L A N L P+ IVE Sbjct: 126 ECSSITILSLNETSLTLLPSNIGSLTNLRVLEARDNLLRTIPLSIVE 172
>LAP1_DROME (Q9V780) Protein lap1| Length = 849 Score = 89.0 bits (219), Expect = 9e-18 Identities = 63/180 (35%), Positives = 92/180 (51%) Frame = +1 Query: 28 VLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPD 207 VL V SN L+S+P +IG L +L+ L+++ NL+ ++P I+ C+ L L+ + N L RLPD Sbjct: 67 VLHVNSNNLESIPQAIGSLRQLQHLDLNRNLIVNVPEEIKSCKHLTHLDLSCNSLQRLPD 126 Query: 208 TLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXX 387 + L SL+ L +N L LP + + LR L+ RLN + Sbjct: 127 AI-TSLISLQELLLNETYLEFLPANFGRLVNLRILELRLNNLMTLPKSMVRLINLQRLDI 185 Query: 388 SQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPLICPPMDI 567 N ELP +G L SLREL I +N I + ++G L L F A GN L P ++ Sbjct: 186 GGN--EFTELPEVVGELKSLRELWIDFNQIRRVSANIGKLRDLQHFEANGNLLDTLPSEL 243 Score = 81.3 bits (199), Expect = 2e-15 Identities = 56/179 (31%), Positives = 85/179 (47%) Frame = +1 Query: 10 RLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQ 189 RL+N+ +L++R N L +LP S+ L L+ L++ GN LP + E ++L EL +FNQ Sbjct: 153 RLVNLRILELRLNNLMTLPKSMVRLINLQRLDIGGNEFTELPEVVGELKSLRELWIDFNQ 212 Query: 190 LTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXX 369 + R+ +G +L L+ N N L +LP S+ + L N + A Sbjct: 213 IRRVSANIG-KLRDLQHFEANGNLLDTLPSELSNWRNVEVLSICSNSLEAFPFSVGMLKS 271 Query: 370 XXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPL 546 N L ELP + L L EL +S+N + LP ++G L L A N L Sbjct: 272 LVTFKCESN--GLTELPDSISYLEQLEELVLSHNKLIRLPSTIGMLRSLRFLFADDNQL 328 Score = 73.6 bits (179), Expect = 4e-13 Identities = 56/188 (29%), Positives = 82/188 (43%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 + RL+N+ LD+ N+ LP +G L LR L + N ++ + A I + R L+ AN Sbjct: 174 MVRLINLQRLDIGGNEFTELPEVVGELKSLRELWIDFNQIRRVSANIGKLRDLQHFEANG 233 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXX 363 N L LP L ++ LS+ SN L + PFS + +L N + Sbjct: 234 NLLDTLPSELS-NWRNVEVLSICSNSLEAFPFSVGMLKSLVTFKCESNGLTELPDSISYL 292 Query: 364 XXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNP 543 S N L LP +G+L SLR L N + LPD + +L+ S N Sbjct: 293 EQLEELVLSHN--KLIRLPSTIGMLRSLRFLFADDNQLRQLPDELCSCQQLSVLSVANNQ 350 Query: 544 LICPPMDI 567 L P +I Sbjct: 351 LSALPQNI 358 Score = 65.9 bits (159), Expect = 8e-11 Identities = 51/188 (27%), Positives = 85/188 (45%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 I L+++ L + L+ LP + G L LR+L + N L +LP ++ L+ L+ Sbjct: 128 ITSLISLQELLLNETYLEFLPANFGRLVNLRILELRLNNLMTLPKSMVRLINLQRLDIGG 187 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXX 363 N+ T LP+ +G EL SLR L ++ N++ + + + L+ +A N + Sbjct: 188 NEFTELPEVVG-ELKSLRELWIDFNQIRRVSANIGKLRDLQHFEANGNLLDTLPSELSNW 246 Query: 364 XXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNP 543 N L P+ +G+L SL N ++ LPDS+ L +L + N Sbjct: 247 RNVEVLSICSN--SLEAFPFSVGMLKSLVTFKCESNGLTELPDSISYLEQLEELVLSHNK 304 Query: 544 LICPPMDI 567 LI P I Sbjct: 305 LIRLPSTI 312 Score = 61.6 bits (148), Expect = 2e-09 Identities = 42/112 (37%), Positives = 63/112 (56%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 + L ++V SN L LP+SI L +L L +S N L LP+TI R+L L A+ Sbjct: 266 VGMLKSLVTFKCESNGLTELPDSISYLEQLEELVLSHNKLIRLPSTIGMLRSLRFLFADD 325 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRA 339 NQL +LPD L L LSV +N+L++LP + +++ ++ L+ N I A Sbjct: 326 NQLRQLPDEL-CSCQQLSVLSVANNQLSALPQNIGNLSKMKVLNVVNNYINA 376 Score = 43.5 bits (101), Expect = 4e-04 Identities = 20/39 (51%), Positives = 29/39 (74%) Frame = +1 Query: 28 VLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATI 144 VL V +NQL +LP +IG LSK++VLNV N + +LP ++ Sbjct: 343 VLSVANNQLSALPQNIGNLSKMKVLNVVNNYINALPVSM 381 Score = 38.5 bits (88), Expect = 0.014 Identities = 23/68 (33%), Positives = 35/68 (51%) Frame = +1 Query: 1 GIARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNAN 180 G+ R L + D NQL+ LP+ + +L VL+V+ N L +LP I ++ LN Sbjct: 313 GMLRSLRFLFAD--DNQLRQLPDELCSCQQLSVLSVANNQLSALPQNIGNLSKMKVLNVV 370 Query: 181 FNQLTRLP 204 N + LP Sbjct: 371 NNYINALP 378
>LRC40_XENLA (Q6GPJ5) Leucine-rich repeat-containing protein 40| Length = 605 Score = 84.7 bits (208), Expect = 2e-16 Identities = 58/182 (31%), Positives = 93/182 (51%), Gaps = 1/182 (0%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 + +L +V ++ SN+L +LP IG + LR L+ + NLL+++PA++ +LE+L Sbjct: 193 VGQLTGLVKFNLSSNKLTALPTEIGKMKNLRQLDCTSNLLENVPASVAGMESLEQLYLRQ 252 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTSL-PFSTSHMTALRALDARLNCIRAXXXXXXX 360 N+LT LP+ L F L L+ L V +N++ +L P ++++L L+ R N ++ Sbjct: 253 NKLTYLPE-LPF-LTKLKELHVGNNQIQTLGPEHLQNLSSLSVLELRYNKLKV------- 303 Query: 361 XXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGN 540 LP + LL L LD+S N I LPD++G L L GN Sbjct: 304 ------------------LPKEISLLKGLERLDLSNNDIGSLPDTLGSLPNLKSLQLDGN 345 Query: 541 PL 546 PL Sbjct: 346 PL 347 Score = 80.1 bits (196), Expect = 4e-15 Identities = 54/176 (30%), Positives = 86/176 (48%) Frame = +1 Query: 31 LDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDT 210 L + SN+L++L I L L VL++ N + SLP I E L++LN + N++ +LP+ Sbjct: 87 LILASNKLQALSEDISLLPALVVLDIHDNQIASLPCAIRELTNLQKLNISHNKIKQLPNE 146 Query: 211 LGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXS 390 L L +L+ + N+L LP S H++ L LD NC+R+ S Sbjct: 147 LQ-HLQNLKSFLLQHNQLEELPDSIGHLSILEELDVSNNCLRSVSSSVGQLTGLVKFNLS 205 Query: 391 QNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPLICPP 558 N L LP +G + +LR+LD + N + +P S+ + L + N L P Sbjct: 206 SN--KLTALPTEIGKMKNLRQLDCTSNLLENVPASVAGMESLEQLYLRQNKLTYLP 259 Score = 47.8 bits (112), Expect = 2e-05 Identities = 29/95 (30%), Positives = 51/95 (53%), Gaps = 1/95 (1%) Frame = +1 Query: 46 NQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDTLGFEL 225 N++ S+ ++ L KL L++ N L SLP +E L+ + +FN+ PD L + + Sbjct: 462 NKISSISLNLCMLLKLTHLDMRNNALASLPPEMEALTRLQSIILSFNRFKHFPDVL-YTI 520 Query: 226 HSLRRLSVNSNKLTSL-PFSTSHMTALRALDARLN 327 +L + ++SN++ S+ P MT L LD + N Sbjct: 521 PNLETILISSNQIGSIDPIQLKKMTKLSTLDLQNN 555 Score = 45.8 bits (107), Expect = 9e-05 Identities = 44/190 (23%), Positives = 78/190 (41%), Gaps = 4/190 (2%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSLPNSI---GCLSKLRVLNVSGNLLQSLPATIEECR-ALEELNAN 180 ++ + L+ Q +P ++ S + +N S N L +PA I E + ++ ++N Sbjct: 401 IMTLKTLEYCEKQASLIPEAVFNAAASSPITTVNFSKNQLTEVPARIVEMKDSVYDVNLG 460 Query: 181 FNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXX 360 FN+++ + L L L L + +N L SLP +T L+++ N + Sbjct: 461 FNKISSISLNLCMLL-KLTHLDMRNNALASLPPEMEALTRLQSIILSFNRFKHFPDVLYT 519 Query: 361 XXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGN 540 S N + P L +T L LD+ N + +P ++G L GN Sbjct: 520 IPNLETILISSNQIGSID-PIQLKKMTKLSTLDLQNNDLLQIPPALGNCESLRALHLEGN 578 Query: 541 PLICPPMDIV 570 P P I+ Sbjct: 579 PFRNPRATIL 588 Score = 44.7 bits (104), Expect = 2e-04 Identities = 30/111 (27%), Positives = 54/111 (48%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 + LL + LD+R+N L SLP + L++L+ + +S N + P + LE + + Sbjct: 471 LCMLLKLTHLDMRNNALASLPPEMEALTRLQSIILSFNRFKHFPDVLYTIPNLETILISS 530 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIR 336 NQ+ + ++ L L + +N L +P + + +LRAL N R Sbjct: 531 NQIGSIDPIQLKKMTKLSTLDLQNNDLLQIPPALGNCESLRALHLEGNPFR 581 Score = 31.6 bits (70), Expect = 1.7 Identities = 14/47 (29%), Positives = 28/47 (59%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATI 144 + ++ + LD+++N L +P ++G LR L++ GN ++ ATI Sbjct: 541 LKKMTKLSTLDLQNNDLLQIPPALGNCESLRALHLEGNPFRNPRATI 587 Score = 31.6 bits (70), Expect = 1.7 Identities = 15/43 (34%), Positives = 27/43 (62%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSL 132 I+ L + LD+ +N + SLP+++G L L+ L + GN L+ + Sbjct: 308 ISLLKGLERLDLSNNDIGSLPDTLGSLPNLKSLQLDGNPLRGI 350
>LRRC1_MOUSE (Q80VQ1) Leucine-rich repeat-containing protein 1| Length = 524 Score = 84.3 bits (207), Expect = 2e-16 Identities = 58/185 (31%), Positives = 89/185 (48%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQL 192 L N+ L V L+SLP +IG L L L + NLL LP ++ + R LEEL+ N++ Sbjct: 127 LQNLTCLSVNDISLQSLPENIGNLYNLASLELRENLLTYLPDSLTQLRRLEELDLGNNEI 186 Query: 193 TRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXX 372 LP+++G LH L+ L ++ N+L+ LP ++ L LD N + Sbjct: 187 YNLPESIGALLH-LKDLWLDGNQLSELPQEIGNLKNLLCLDVSENRLERLPEEISGLTSL 245 Query: 373 XXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPLIC 552 SQN L +P G+G L L L + N ++ LP+++G L + N L+ Sbjct: 246 TYLVISQN--LLETIPEGIGKLKKLSILKLDQNRLTQLPEAIGDCENLTELVLTENRLLT 303 Query: 553 PPMDI 567 P I Sbjct: 304 LPKSI 308 Score = 72.0 bits (175), Expect = 1e-12 Identities = 56/171 (32%), Positives = 78/171 (45%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 IA + +V LDV N + +P SI L+V + SGN L LP + E + L L+ N Sbjct: 78 IANFMQLVELDVSRNDIPEIPESIAFCKALQVADFSGNPLTRLPESFPELQNLTCLSVND 137 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXX 363 L LP+ +G L++L L + N LT LP S + + L LD N I Sbjct: 138 ISLQSLPENIG-NLYNLASLELRENLLTYLPDSLTQLRRLEELDLGNNEIYNLPESIGAL 196 Query: 364 XXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKL 516 N L ELP +G L +L LD+S N + LP+ + L L Sbjct: 197 LHLKDLWLDGN--QLSELPQEIGNLKNLLCLDVSENRLERLPEEISGLTSL 245 Score = 71.6 bits (174), Expect = 1e-12 Identities = 60/187 (32%), Positives = 83/187 (44%) Frame = +1 Query: 7 ARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFN 186 AR L ++LD +NQL+ LP L KLR L +S N +Q LP I L EL+ + N Sbjct: 35 ARSLEELLLD--ANQLRELPEQFFQLVKLRKLGLSDNEIQRLPPEIANFMQLVELDVSRN 92 Query: 187 QLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXX 366 + +P+++ F +L+ + N LT LP S + L L +N I Sbjct: 93 DIPEIPESIAF-CKALQVADFSGNPLTRLPESFPELQNLTCLS--VNDISLQSLPENIGN 149 Query: 367 XXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPL 546 + L LP L L L ELD+ N I LP+S+G L L GN L Sbjct: 150 LYNLASLELRENLLTYLPDSLTQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDGNQL 209 Query: 547 ICPPMDI 567 P +I Sbjct: 210 SELPQEI 216 Score = 67.8 bits (164), Expect = 2e-11 Identities = 51/168 (30%), Positives = 81/168 (48%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 I L N++ LDV N+L+ LP I L+ L L +S NLL+++P I + + L L + Sbjct: 216 IGNLKNLLCLDVSENRLERLPEEISGLTSLTYLVISQNLLETIPEGIGKLKKLSILKLDQ 275 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXX 363 N+LT+LP+ +G + +L L + N+L +LP S + L L+A N + + Sbjct: 276 NRLTQLPEAIG-DCENLTELVLTENRLLTLPKSIGKLKKLSNLNADRNKLVSLPKEIGGC 334 Query: 364 XXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCL 507 N L LP + L LD++ N + LP S+ L Sbjct: 335 CSLTMFCIRDN--RLTRLPAEVSQAVELHVLDVAGNRLHHLPLSLTTL 380 Score = 60.1 bits (144), Expect = 4e-09 Identities = 38/109 (34%), Positives = 55/109 (50%) Frame = +1 Query: 1 GIARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNAN 180 GI +L + +L + N+L LP +IG L L ++ N L +LP +I + + L LNA+ Sbjct: 261 GIGKLKKLSILKLDQNRLTQLPEAIGDCENLTELVLTENRLLTLPKSIGKLKKLSNLNAD 320 Query: 181 FNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLN 327 N+L LP +G SL + N+LT LP S L LD N Sbjct: 321 RNKLVSLPKEIG-GCCSLTMFCIRDNRLTRLPAEVSQAVELHVLDVAGN 368 Score = 34.3 bits (77), Expect = 0.26 Identities = 34/140 (24%), Positives = 51/140 (36%) Frame = +1 Query: 154 RALEELNANFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCI 333 R +E ++ L +P+ + SL L +++N+L LP + LR L N I Sbjct: 12 RHVEAIDKRHCSLVYVPEEIYRYARSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEI 71 Query: 334 RAXXXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAK 513 + LP + L ELD+S N I +P+S+ Sbjct: 72 Q-------------------------RLPPEIANFMQLVELDVSRNDIPEIPESIAFCKA 106 Query: 514 LNKFSAVGNPLICPPMDIVE 573 L GNPL P E Sbjct: 107 LQVADFSGNPLTRLPESFPE 126
>LRRC1_HUMAN (Q9BTT6) Leucine-rich repeat-containing protein 1 (LAP and no PDZ| protein) (LANO adapter protein) Length = 524 Score = 84.3 bits (207), Expect = 2e-16 Identities = 58/185 (31%), Positives = 89/185 (48%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQL 192 L N+ L V L+SLP +IG L L L + NLL LP ++ + R LEEL+ N++ Sbjct: 127 LQNLTCLSVNDISLQSLPENIGNLYNLASLELRENLLTYLPDSLTQLRRLEELDLGNNEI 186 Query: 193 TRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXX 372 LP+++G LH L+ L ++ N+L+ LP ++ L LD N + Sbjct: 187 YNLPESIGALLH-LKDLWLDGNQLSELPQEIGNLKNLLCLDVSENRLERLPEEISGLTSL 245 Query: 373 XXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPLIC 552 SQN L +P G+G L L L + N ++ LP+++G L + N L+ Sbjct: 246 TDLVISQN--LLETIPDGIGKLKKLSILKVDQNRLTQLPEAVGECESLTELVLTENQLLT 303 Query: 553 PPMDI 567 P I Sbjct: 304 LPKSI 308 Score = 72.8 bits (177), Expect = 7e-13 Identities = 56/171 (32%), Positives = 79/171 (46%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 IA + +V LDV N++ +P SI L+V + SGN L LP + E + L L+ N Sbjct: 78 IANFMQLVELDVSRNEIPEIPESISFCKALQVADFSGNPLTRLPESFPELQNLTCLSVND 137 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXX 363 L LP+ +G L++L L + N LT LP S + + L LD N I Sbjct: 138 ISLQSLPENIG-NLYNLASLELRENLLTYLPDSLTQLRRLEELDLGNNEIYNLPESIGAL 196 Query: 364 XXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKL 516 N L ELP +G L +L LD+S N + LP+ + L L Sbjct: 197 LHLKDLWLDGN--QLSELPQEIGNLKNLLCLDVSENRLERLPEEISGLTSL 245 Score = 72.4 bits (176), Expect = 9e-13 Identities = 60/187 (32%), Positives = 84/187 (44%) Frame = +1 Query: 7 ARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFN 186 AR L ++LD +NQL+ LP L KLR L +S N +Q LP I L EL+ + N Sbjct: 35 ARSLEELLLD--ANQLRELPEQFFQLVKLRKLGLSDNEIQRLPPEIANFMQLVELDVSRN 92 Query: 187 QLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXX 366 ++ +P+++ F +L+ + N LT LP S + L L +N I Sbjct: 93 EIPEIPESISF-CKALQVADFSGNPLTRLPESFPELQNLTCLS--VNDISLQSLPENIGN 149 Query: 367 XXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPL 546 + L LP L L L ELD+ N I LP+S+G L L GN L Sbjct: 150 LYNLASLELRENLLTYLPDSLTQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDGNQL 209 Query: 547 ICPPMDI 567 P +I Sbjct: 210 SELPQEI 216 Score = 69.7 bits (169), Expect = 6e-12 Identities = 53/168 (31%), Positives = 82/168 (48%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 I L N++ LDV N+L+ LP I L+ L L +S NLL+++P I + + L L + Sbjct: 216 IGNLKNLLCLDVSENRLERLPEEISGLTSLTDLVISQNLLETIPDGIGKLKKLSILKVDQ 275 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXX 363 N+LT+LP+ +G E SL L + N+L +LP S + L L+A N + + Sbjct: 276 NRLTQLPEAVG-ECESLTELVLTENQLLTLPKSIGKLKKLSNLNADRNKLVSLPKEIGGC 334 Query: 364 XXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCL 507 N L +P + T L LD++ N + LP S+ L Sbjct: 335 CSLTVFCVRDN--RLTRIPAEVSQATELHVLDVAGNRLLHLPLSLTAL 380 Score = 61.2 bits (147), Expect = 2e-09 Identities = 39/109 (35%), Positives = 56/109 (51%) Frame = +1 Query: 1 GIARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNAN 180 GI +L + +L V N+L LP ++G L L ++ N L +LP +I + + L LNA+ Sbjct: 261 GIGKLKKLSILKVDQNRLTQLPEAVGECESLTELVLTENQLLTLPKSIGKLKKLSNLNAD 320 Query: 181 FNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLN 327 N+L LP +G SL V N+LT +P S T L LD N Sbjct: 321 RNKLVSLPKEIG-GCCSLTVFCVRDNRLTRIPAEVSQATELHVLDVAGN 368 Score = 34.7 bits (78), Expect = 0.20 Identities = 34/140 (24%), Positives = 51/140 (36%) Frame = +1 Query: 154 RALEELNANFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCI 333 R +E ++ L +P+ + SL L +++N+L LP + LR L N I Sbjct: 12 RHVESIDKRHCSLVYVPEEIYRYARSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEI 71 Query: 334 RAXXXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAK 513 + LP + L ELD+S N I +P+S+ Sbjct: 72 Q-------------------------RLPPEIANFMQLVELDVSRNEIPEIPESISFCKA 106 Query: 514 LNKFSAVGNPLICPPMDIVE 573 L GNPL P E Sbjct: 107 LQVADFSGNPLTRLPESFPE 126
>LRRC7_RAT (P70587) Leucine-rich repeat-containing protein 7 (LAP1 protein)| (Densin-180) Length = 1495 Score = 83.6 bits (205), Expect = 4e-16 Identities = 59/189 (31%), Positives = 94/189 (49%) Frame = +1 Query: 1 GIARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNAN 180 G +LLN+ L + L+ LP + G L KLR+L + N L++LP ++ + LE L+ Sbjct: 138 GFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMHKLAQLERLDLG 197 Query: 181 FNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXX 360 N+ + LP+ L ++ +LR L +++N L LP S + L LD N I Sbjct: 198 NNEFSELPEVLD-QIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISG 256 Query: 361 XXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGN 540 S N L++LP +GLL L L + N +++LP+++G L+ L +F N Sbjct: 257 CEALEDLLLSSN--MLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCN 314 Query: 541 PLICPPMDI 567 L P I Sbjct: 315 ELESLPPTI 323 Score = 78.2 bits (191), Expect = 2e-14 Identities = 52/179 (29%), Positives = 89/179 (49%) Frame = +1 Query: 10 RLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQ 189 ++ N+ L + +N L+ LP SIG L L L++S N ++++ I C ALE+L + N Sbjct: 210 QIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNM 269 Query: 190 LTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXX 369 L +LPD++G L L L V+ N+LT LP + +++ L D N + + Sbjct: 270 LQQLPDSIGL-LKKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPPTIGYLHS 328 Query: 370 XXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPL 546 +N FL ELP +G ++ + + N + LP+ +G + +L + N L Sbjct: 329 LRTLAVDEN--FLPELPREIGSCKNVTVMSLRSNKLEFLPEEIGQMQRLRVLNLSDNRL 385 Score = 72.8 bits (177), Expect = 7e-13 Identities = 55/158 (34%), Positives = 72/158 (45%) Frame = +1 Query: 43 SNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDTLGFE 222 SN L+ LP+SIG L KL L V N L LP TI LEE + + N+L LP T+G+ Sbjct: 267 SNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPPTIGY- 325 Query: 223 LHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFH 402 LHSLR L+V+ N L LP + + R N Sbjct: 326 LHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSN------------------------- 360 Query: 403 FLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKL 516 L LP +G + LR L++S N + LP S L +L Sbjct: 361 KLEFLPEEIGQMQRLRVLNLSDNRLKNLPFSFTKLKEL 398 Score = 62.4 bits (150), Expect = 9e-10 Identities = 60/210 (28%), Positives = 91/210 (43%), Gaps = 24/210 (11%) Frame = +1 Query: 10 RLLNVVVLDVRSNQLKS-----------------------LPNSIGCLSKLRVLNVSGNL 120 R L + LD +NQ++ LP SI L L+ L++S N Sbjct: 51 RTLEELYLD--ANQIEELPKQLFNCQALRKLSIPDNDLSSLPTSIASLVNLKELDISKNG 108 Query: 121 LQSLPATIEECRALEELNANFNQLTRLPDTLGF-ELHSLRRLSVNSNKLTSLPFSTSHMT 297 +Q P I+ C+ L + A+ N +++LPD GF +L +L +L +N L LP + + Sbjct: 109 VQEFPENIKCCKCLTIIEASVNPISKLPD--GFTQLLNLTQLYLNDAFLEFLPANFGRLV 166 Query: 298 ALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSI 477 LR L+ R N ++ N ELP L + +LREL + N++ Sbjct: 167 KLRILELRENHLKTLPKSMHKLAQLERLDLGNN--EFSELPEVLDQIQNLRELWMDNNAL 224 Query: 478 SVLPDSMGCLAKLNKFSAVGNPLICPPMDI 567 VLP S+G L L N + MDI Sbjct: 225 QVLPGSIGKLKMLVYLDMSKNRIETVDMDI 254 Score = 59.3 bits (142), Expect = 8e-09 Identities = 42/111 (37%), Positives = 56/111 (50%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 I L + L V NQL LPN+IG LS L + S N L+SLP TI +L L + Sbjct: 277 IGLLKKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPPTIGYLHSLRTLAVDE 336 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIR 336 N L LP +G ++ +S+ SNKL LP M LR L+ N ++ Sbjct: 337 NFLPELPREIG-SCKNVTVMSLRSNKLEFLPEEIGQMQRLRVLNLSDNRLK 386 Score = 48.9 bits (115), Expect = 1e-05 Identities = 25/57 (43%), Positives = 38/57 (66%) Frame = +1 Query: 19 NVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQ 189 NV V+ +RSN+L+ LP IG + +LRVLN+S N L++LP + + + L L + NQ Sbjct: 351 NVTVMSLRSNKLEFLPEEIGQMQRLRVLNLSDNRLKNLPFSFTKLKELAALWLSDNQ 407
>LRRC7_MOUSE (Q80TE7) Leucine-rich repeat-containing protein 7 (LAP1 protein)| (Densin-180) Length = 1490 Score = 83.6 bits (205), Expect = 4e-16 Identities = 59/189 (31%), Positives = 94/189 (49%) Frame = +1 Query: 1 GIARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNAN 180 G +LLN+ L + L+ LP + G L KLR+L + N L++LP ++ + LE L+ Sbjct: 133 GFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMHKLAQLERLDLG 192 Query: 181 FNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXX 360 N+ + LP+ L ++ +LR L +++N L LP S + L LD N I Sbjct: 193 NNEFSELPEVLD-QIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISG 251 Query: 361 XXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGN 540 S N L++LP +GLL L L + N +++LP+++G L+ L +F N Sbjct: 252 CEALEDLLLSSN--MLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCN 309 Query: 541 PLICPPMDI 567 L P I Sbjct: 310 ELESLPPTI 318 Score = 78.2 bits (191), Expect = 2e-14 Identities = 52/179 (29%), Positives = 89/179 (49%) Frame = +1 Query: 10 RLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQ 189 ++ N+ L + +N L+ LP SIG L L L++S N ++++ I C ALE+L + N Sbjct: 205 QIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNM 264 Query: 190 LTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXX 369 L +LPD++G L L L V+ N+LT LP + +++ L D N + + Sbjct: 265 LQQLPDSIGL-LKKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPPTIGYLHS 323 Query: 370 XXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPL 546 +N FL ELP +G ++ + + N + LP+ +G + +L + N L Sbjct: 324 LRTLAVDEN--FLPELPREIGSCKNVTVMSLRSNKLEFLPEEIGQMQRLRVLNLSDNRL 380 Score = 72.8 bits (177), Expect = 7e-13 Identities = 55/158 (34%), Positives = 72/158 (45%) Frame = +1 Query: 43 SNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDTLGFE 222 SN L+ LP+SIG L KL L V N L LP TI LEE + + N+L LP T+G+ Sbjct: 262 SNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPPTIGY- 320 Query: 223 LHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFH 402 LHSLR L+V+ N L LP + + R N Sbjct: 321 LHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSN------------------------- 355 Query: 403 FLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKL 516 L LP +G + LR L++S N + LP S L +L Sbjct: 356 KLEFLPEEIGQMQRLRVLNLSDNRLKNLPFSFTKLKEL 393 Score = 62.4 bits (150), Expect = 9e-10 Identities = 60/210 (28%), Positives = 91/210 (43%), Gaps = 24/210 (11%) Frame = +1 Query: 10 RLLNVVVLDVRSNQLKS-----------------------LPNSIGCLSKLRVLNVSGNL 120 R L + LD +NQ++ LP SI L L+ L++S N Sbjct: 46 RTLEELYLD--ANQIEELPKQLFNCQALRKLSIPDNDLSSLPTSIASLVNLKELDISKNG 103 Query: 121 LQSLPATIEECRALEELNANFNQLTRLPDTLGF-ELHSLRRLSVNSNKLTSLPFSTSHMT 297 +Q P I+ C+ L + A+ N +++LPD GF +L +L +L +N L LP + + Sbjct: 104 VQEFPENIKCCKCLTIIEASVNPISKLPD--GFTQLLNLTQLYLNDAFLEFLPANFGRLV 161 Query: 298 ALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSI 477 LR L+ R N ++ N ELP L + +LREL + N++ Sbjct: 162 KLRILELRENHLKTLPKSMHKLAQLERLDLGNN--EFSELPEVLDQIQNLRELWMDNNAL 219 Query: 478 SVLPDSMGCLAKLNKFSAVGNPLICPPMDI 567 VLP S+G L L N + MDI Sbjct: 220 QVLPGSIGKLKMLVYLDMSKNRIETVDMDI 249 Score = 59.3 bits (142), Expect = 8e-09 Identities = 42/111 (37%), Positives = 56/111 (50%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 I L + L V NQL LPN+IG LS L + S N L+SLP TI +L L + Sbjct: 272 IGLLKKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPPTIGYLHSLRTLAVDE 331 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIR 336 N L LP +G ++ +S+ SNKL LP M LR L+ N ++ Sbjct: 332 NFLPELPREIG-SCKNVTVMSLRSNKLEFLPEEIGQMQRLRVLNLSDNRLK 381 Score = 48.9 bits (115), Expect = 1e-05 Identities = 25/57 (43%), Positives = 38/57 (66%) Frame = +1 Query: 19 NVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQ 189 NV V+ +RSN+L+ LP IG + +LRVLN+S N L++LP + + + L L + NQ Sbjct: 346 NVTVMSLRSNKLEFLPEEIGQMQRLRVLNLSDNRLKNLPFSFTKLKELAALWLSDNQ 402
>LRRC7_HUMAN (Q96NW7) Leucine-rich repeat-containing protein 7 (LAP1 protein)| (Densin-180) Length = 1537 Score = 82.8 bits (203), Expect = 6e-16 Identities = 59/189 (31%), Positives = 93/189 (49%) Frame = +1 Query: 1 GIARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNAN 180 G +LLN+ L + L+ LP + G L KLR+L + N L++LP ++ + LE L+ Sbjct: 133 GFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMHKLAQLERLDLG 192 Query: 181 FNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXX 360 N+ LP+ L ++ +LR L +++N L LP S + L LD N I Sbjct: 193 NNEFGELPEVLD-QIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISG 251 Query: 361 XXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGN 540 S N L++LP +GLL L L + N +++LP+++G L+ L +F N Sbjct: 252 CEALEDLLLSSN--MLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCN 309 Query: 541 PLICPPMDI 567 L P I Sbjct: 310 ELESLPSTI 318 Score = 80.1 bits (196), Expect = 4e-15 Identities = 53/179 (29%), Positives = 89/179 (49%) Frame = +1 Query: 10 RLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQ 189 ++ N+ L + +N L+ LP SIG L L L++S N ++++ I C ALE+L + N Sbjct: 205 QIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNM 264 Query: 190 LTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXX 369 L +LPD++G L L L V+ N+LT LP + +++ L D N + + Sbjct: 265 LQQLPDSIGL-LKKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIGYLHS 323 Query: 370 XXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPL 546 +N FL ELP +G ++ + + N + LP+ +G + KL + N L Sbjct: 324 LRTLAVDEN--FLPELPREIGSCKNVTVMSLRSNKLEFLPEEIGQMQKLRVLNLSDNRL 380 Score = 73.6 bits (179), Expect = 4e-13 Identities = 55/158 (34%), Positives = 72/158 (45%) Frame = +1 Query: 43 SNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDTLGFE 222 SN L+ LP+SIG L KL L V N L LP TI LEE + + N+L LP T+G+ Sbjct: 262 SNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIGY- 320 Query: 223 LHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFH 402 LHSLR L+V+ N L LP + + R N Sbjct: 321 LHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSN------------------------- 355 Query: 403 FLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKL 516 L LP +G + LR L++S N + LP S L +L Sbjct: 356 KLEFLPEEIGQMQKLRVLNLSDNRLKNLPFSFTKLKEL 393 Score = 65.5 bits (158), Expect = 1e-10 Identities = 36/93 (38%), Positives = 56/93 (60%) Frame = +1 Query: 34 DVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDTL 213 D N+L+SLP++IG L LR L V N L LP I C+ + ++ N+L LP+ + Sbjct: 305 DCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLEFLPEEI 364 Query: 214 GFELHSLRRLSVNSNKLTSLPFSTSHMTALRAL 312 G ++ LR L+++ N+L +LPFS + + L AL Sbjct: 365 G-QMQKLRVLNLSDNRLKNLPFSFTKLKELAAL 396 Score = 60.8 bits (146), Expect = 3e-09 Identities = 59/210 (28%), Positives = 91/210 (43%), Gaps = 24/210 (11%) Frame = +1 Query: 10 RLLNVVVLDVRSNQLKS-----------------------LPNSIGCLSKLRVLNVSGNL 120 R L + LD +NQ++ LP +I L L+ L++S N Sbjct: 46 RTLEELYLD--ANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNG 103 Query: 121 LQSLPATIEECRALEELNANFNQLTRLPDTLGF-ELHSLRRLSVNSNKLTSLPFSTSHMT 297 +Q P I+ C+ L + A+ N +++LPD GF +L +L +L +N L LP + + Sbjct: 104 VQEFPENIKCCKCLTIIEASVNPISKLPD--GFTQLLNLTQLYLNDAFLEFLPANFGRLV 161 Query: 298 ALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSI 477 LR L+ R N ++ N ELP L + +LREL + N++ Sbjct: 162 KLRILELRENHLKTLPKSMHKLAQLERLDLGNN--EFGELPEVLDQIQNLRELWMDNNAL 219 Query: 478 SVLPDSMGCLAKLNKFSAVGNPLICPPMDI 567 VLP S+G L L N + MDI Sbjct: 220 QVLPGSIGKLKMLVYLDMSKNRIETVDMDI 249 Score = 60.1 bits (144), Expect = 4e-09 Identities = 42/111 (37%), Positives = 57/111 (51%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 I L + L V NQL LPN+IG LS L + S N L+SLP+TI +L L + Sbjct: 272 IGLLKKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDE 331 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIR 336 N L LP +G ++ +S+ SNKL LP M LR L+ N ++ Sbjct: 332 NFLPELPREIG-SCKNVTVMSLRSNKLEFLPEEIGQMQKLRVLNLSDNRLK 381 Score = 50.1 bits (118), Expect = 5e-06 Identities = 26/57 (45%), Positives = 38/57 (66%) Frame = +1 Query: 19 NVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQ 189 NV V+ +RSN+L+ LP IG + KLRVLN+S N L++LP + + + L L + NQ Sbjct: 346 NVTVMSLRSNKLEFLPEEIGQMQKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDNQ 402
>LRC40_XENTR (Q5M8G4) Leucine-rich repeat-containing protein 40| Length = 605 Score = 82.0 bits (201), Expect = 1e-15 Identities = 59/202 (29%), Positives = 94/202 (46%), Gaps = 21/202 (10%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 + L N+ L ++ NQL+ LP+SIG LS L L+VS N L+S+ +++ + L + N + Sbjct: 147 LQHLQNLKSLLLQHNQLEELPDSIGHLSILEELDVSNNCLRSISSSVGQLTGLVKFNLSS 206 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIR--------- 336 N+LT LP +G ++ +L++L SN L ++P S + M +L L R N + Sbjct: 207 NKLTALPTEIG-KMKNLKQLDCTSNLLENVPASVAGMESLEQLYLRQNKLTYLPELPFLT 265 Query: 337 ------------AXXXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSIS 480 ++ L+ LP + LL L LD+S N + Sbjct: 266 KLKELHVGNNQIQTLGPEHLQNLSSLSVLELRYNKLKVLPEEISLLNGLERLDLSNNDLG 325 Query: 481 VLPDSMGCLAKLNKFSAVGNPL 546 LP ++G L L GNPL Sbjct: 326 SLPCTLGSLPNLKSLQLEGNPL 347 Score = 79.7 bits (195), Expect = 5e-15 Identities = 64/212 (30%), Positives = 97/212 (45%), Gaps = 24/212 (11%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 I+ L +VVLD+ NQ+ SLP +I L+ L+ LN+S N ++ LP ++ + L+ L Sbjct: 101 ISLLPALVVLDIHDNQIVSLPCAIKELTNLQKLNISHNKIKQLPKELQHLQNLKSLLLQH 160 Query: 184 NQLTRLPDTLGF----------------------ELHSLRRLSVNSNKLTSLPFSTSHMT 297 NQL LPD++G +L L + +++SNKLT+LP M Sbjct: 161 NQLEELPDSIGHLSILEELDVSNNCLRSISSSVGQLTGLVKFNLSSNKLTALPTEIGKMK 220 Query: 298 ALRALDARLNCIRAXXXXXXXXXXXXXXXXSQN-FHFLRELPYGLGLLTSLRELDISYNS 474 L+ LD N + QN +L ELP+ LT L+EL + N Sbjct: 221 NLKQLDCTSNLLENVPASVAGMESLEQLYLRQNKLTYLPELPF----LTKLKELHVGNNQ 276 Query: 475 ISVL-PDSMGCLAKLNKFSAVGNPLICPPMDI 567 I L P+ + L+ L+ N L P +I Sbjct: 277 IQTLGPEHLQNLSSLSVLELRYNKLKVLPEEI 308 Score = 78.6 bits (192), Expect = 1e-14 Identities = 54/176 (30%), Positives = 86/176 (48%) Frame = +1 Query: 31 LDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDT 210 L + SN+L+ L I L L VL++ N + SLP I+E L++LN + N++ +LP Sbjct: 87 LILASNKLQLLSEDISLLPALVVLDIHDNQIVSLPCAIKELTNLQKLNISHNKIKQLPKE 146 Query: 211 LGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXS 390 L L +L+ L + N+L LP S H++ L LD NC+R+ S Sbjct: 147 LQ-HLQNLKSLLLQHNQLEELPDSIGHLSILEELDVSNNCLRSISSSVGQLTGLVKFNLS 205 Query: 391 QNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPLICPP 558 N L LP +G + +L++LD + N + +P S+ + L + N L P Sbjct: 206 SN--KLTALPTEIGKMKNLKQLDCTSNLLENVPASVAGMESLEQLYLRQNKLTYLP 259 Score = 48.1 bits (113), Expect = 2e-05 Identities = 29/111 (26%), Positives = 56/111 (50%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 + LL + +D+R+N L SLP+ + +++L+ + +S N + P + LE + + Sbjct: 471 LCMLLKLTHIDMRNNVLTSLPSEMEAMTRLQSVILSFNRFKHFPDVLYRIPTLETILISS 530 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIR 336 NQ+ + T ++ L L + +N L +P + + +LRAL N R Sbjct: 531 NQIGSIDPTQLIKMTKLSTLDLQNNDLLQIPPALGNCESLRALHLEGNPFR 581 Score = 47.0 bits (110), Expect = 4e-05 Identities = 28/95 (29%), Positives = 53/95 (55%), Gaps = 1/95 (1%) Frame = +1 Query: 46 NQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDTLGFEL 225 N++ S+ ++ L KL +++ N+L SLP+ +E L+ + +FN+ PD L + + Sbjct: 462 NKISSISLNLCMLLKLTHIDMRNNVLTSLPSEMEAMTRLQSVILSFNRFKHFPDVL-YRI 520 Query: 226 HSLRRLSVNSNKLTSL-PFSTSHMTALRALDARLN 327 +L + ++SN++ S+ P MT L LD + N Sbjct: 521 PTLETILISSNQIGSIDPTQLIKMTKLSTLDLQNN 555 Score = 43.5 bits (101), Expect = 4e-04 Identities = 41/158 (25%), Positives = 67/158 (42%), Gaps = 1/158 (0%) Frame = +1 Query: 85 SKLRVLNVSGNLLQSLPATIEECR-ALEELNANFNQLTRLPDTLGFELHSLRRLSVNSNK 261 S + +N S N L +PA I E + ++ ++N FN+++ + L L L + + +N Sbjct: 428 SFITTVNFSKNQLTEVPARIVEMKDSVCDVNLGFNKISSISLNLCMLL-KLTHIDMRNNV 486 Query: 262 LTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLT 441 LTSLP MT L+++ N + S N + P L +T Sbjct: 487 LTSLPSEMEAMTRLQSVILSFNRFKHFPDVLYRIPTLETILISSNQIGSID-PTQLIKMT 545 Query: 442 SLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPLICP 555 L LD+ N + +P ++G L GNP P Sbjct: 546 KLSTLDLQNNDLLQIPPALGNCESLRALHLEGNPFRNP 583 Score = 31.6 bits (70), Expect = 1.7 Identities = 39/182 (21%), Positives = 77/182 (42%), Gaps = 3/182 (1%) Frame = +1 Query: 31 LDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPD- 207 LD+ +N L SLP ++G L L+ L + GN L+ + I + +EL ++PD Sbjct: 317 LDLSNNDLGSLPCTLGSLPNLKSLQLEGNPLRGIRRDILN-KGTQELLKYLKGRVQVPDV 375 Query: 208 -TLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXX 384 T E + +++ S + + + + L + + + I Sbjct: 376 KTQEDENSTATAMTLPSESVVN-THAIVTLKTLEYCEKQASLIPEAVFNATGSSFITTVN 434 Query: 385 XSQNFHFLRELPYGL-GLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPLICPPM 561 S+N L E+P + + S+ ++++ +N IS + ++ L KL N L P Sbjct: 435 FSKN--QLTEVPARIVEMKDSVCDVNLGFNKISSISLNLCMLLKLTHIDMRNNVLTSLPS 492 Query: 562 DI 567 ++ Sbjct: 493 EM 494
>LRC40_BRARE (Q7SXW3) Leucine-rich repeat-containing protein 40| Length = 601 Score = 81.6 bits (200), Expect = 1e-15 Identities = 58/182 (31%), Positives = 90/182 (49%), Gaps = 1/182 (0%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 +A L N+V LD+ N+LKSLP +I + LR+L+ S N ++S+P + + +LE+L Sbjct: 191 LANLQNLVKLDLSCNKLKSLPPAISQMKNLRMLDCSRNQMESIPPVLAQMESLEQLYLRH 250 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFS-TSHMTALRALDARLNCIRAXXXXXXX 360 N+L LP+ + +L+ L +N++ L H+ AL L+ R N +++ Sbjct: 251 NKLRYLPELPCCK--TLKELHCGNNQIEVLEAEHLKHLNALSLLELRDNKVKS------- 301 Query: 361 XXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGN 540 LP + LL L LD++ N IS LP +G L KL S GN Sbjct: 302 ------------------LPEEITLLQGLERLDLTNNDISSLPCGLGTLPKLKSLSLEGN 343 Query: 541 PL 546 PL Sbjct: 344 PL 345 Score = 67.4 bits (163), Expect = 3e-11 Identities = 50/152 (32%), Positives = 74/152 (48%) Frame = +1 Query: 91 LRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDTLGFELHSLRRLSVNSNKLTS 270 L L +S N LQS+P ++ AL L+ + NQL+ LPD++G +L L++L ++ NKLT Sbjct: 82 LTKLLLSSNKLQSIPDDVKLLPALVVLDIHDNQLSSLPDSIG-DLEQLQKLILSHNKLTE 140 Query: 271 LPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLR 450 LP +T LR L + N I ++P LG L +L Sbjct: 141 LPSGVWRLTNLRCLHLQQNLI-------------------------EQIPRDLGQLVNLD 175 Query: 451 ELDISYNSISVLPDSMGCLAKLNKFSAVGNPL 546 ELD+S N + +P+S+ L L K N L Sbjct: 176 ELDLSNNHLIDIPESLANLQNLVKLDLSCNKL 207 Score = 60.5 bits (145), Expect = 3e-09 Identities = 47/168 (27%), Positives = 77/168 (45%) Frame = +1 Query: 43 SNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDTLGFE 222 SN+L+S+P+ + L L VL++ N L SLP +I + L++L + N+LT LP + + Sbjct: 89 SNKLQSIPDDVKLLPALVVLDIHDNQLSSLPDSIGDLEQLQKLILSHNKLTELPSGV-WR 147 Query: 223 LHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFH 402 L +LR L + N + +P + L LD N + S N Sbjct: 148 LTNLRCLHLQQNLIEQIPRDLGQLVNLDELDLSNNHLIDIPESLANLQNLVKLDLSCN-- 205 Query: 403 FLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPL 546 L+ LP + + +LR LD S N + +P + + L + N L Sbjct: 206 KLKSLPPAISQMKNLRMLDCSRNQMESIPPVLAQMESLEQLYLRHNKL 253 Score = 50.1 bits (118), Expect = 5e-06 Identities = 46/153 (30%), Positives = 65/153 (42%) Frame = +1 Query: 100 LNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPF 279 LN+SG L +PA++ A N D +E L +L ++SNKL S+P Sbjct: 39 LNLSGRGLTEVPASVWRLNLDTPQEAKQNVSFGAEDRW-WEQTDLTKLLLSSNKLQSIPD 97 Query: 280 STSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELD 459 + AL LD N + + S N L ELP G+ LT+LR L Sbjct: 98 DVKLLPALVVLDIHDNQLSSLPDSIGDLEQLQKLILSHN--KLTELPSGVWRLTNLRCLH 155 Query: 460 ISYNSISVLPDSMGCLAKLNKFSAVGNPLICPP 558 + N I +P +G L L++ N LI P Sbjct: 156 LQQNLIEQIPRDLGQLVNLDELDLSNNHLIDIP 188 Score = 44.7 bits (104), Expect = 2e-04 Identities = 30/100 (30%), Positives = 52/100 (52%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQL 192 L ++ +D+R+N L SLP + L KLR + +S N +S P + +LE + + NQ+ Sbjct: 470 LKQLMHIDLRNNLLISLPMELEGLIKLRSVILSFNRFKSFPEVLYRIPSLETILISSNQV 529 Query: 193 TRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRAL 312 + L L L +++N + +P + T+LRAL Sbjct: 530 GGIDAVQMKTLSRLSTLDLSNNDIMQVPPELGNCTSLRAL 569 Score = 43.1 bits (100), Expect = 6e-04 Identities = 39/153 (25%), Positives = 63/153 (41%), Gaps = 1/153 (0%) Frame = +1 Query: 100 LNVSGNLLQSLPATIEECR-ALEELNANFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLP 276 +N S N L ++P I + + +L ++N FN+LT +P L L + + +N L SLP Sbjct: 429 VNFSKNQLTAVPHRIVDLKDSLADINLGFNKLTTIPADF-CHLKQLMHIDLRNNLLISLP 487 Query: 277 FSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLREL 456 + LR++ N ++ S N + + L+ L L Sbjct: 488 MELEGLIKLRSVILSFNRFKSFPEVLYRIPSLETILISSNQVGGIDAVQ-MKTLSRLSTL 546 Query: 457 DISYNSISVLPDSMGCLAKLNKFSAVGNPLICP 555 D+S N I +P +G L GNP P Sbjct: 547 DLSNNDIMQVPPELGNCTSLRALMLDGNPFRNP 579 Score = 37.0 bits (84), Expect = 0.040 Identities = 21/73 (28%), Positives = 40/73 (54%) Frame = +1 Query: 46 NQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDTLGFEL 225 N+L ++P L +L +++ NLL SLP +E L + +FN+ P+ L + + Sbjct: 458 NKLTTIPADFCHLKQLMHIDLRNNLLISLPMELEGLIKLRSVILSFNRFKSFPEVL-YRI 516 Query: 226 HSLRRLSVNSNKL 264 SL + ++SN++ Sbjct: 517 PSLETILISSNQV 529 Score = 32.7 bits (73), Expect = 0.75 Identities = 14/34 (41%), Positives = 24/34 (70%) Frame = +1 Query: 31 LDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSL 132 LD+ +N + SLP +G L KL+ L++ GN L+++ Sbjct: 315 LDLTNNDISSLPCGLGTLPKLKSLSLEGNPLRAI 348
>LAP4_HUMAN (Q14160) LAP4 protein (Scribble homolog protein) (hScrib)| Length = 1630 Score = 81.3 bits (199), Expect = 2e-15 Identities = 64/188 (34%), Positives = 88/188 (46%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 + L N+V L++R N LKSLP S+ L KL L++ GN L+ LP T+ L EL + Sbjct: 147 VGNLANLVTLELRENLLKSLPASLSFLVKLEQLDLGGNDLEVLPDTLGALPNLRELWLDR 206 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXX 363 NQL+ LP LG L L L V+ N+L LP + L L N +R Sbjct: 207 NQLSALPPELG-NLRRLVCLDVSENRLEELPAELGGLVLLTDLLLSQNLLRRLPDGIGQL 265 Query: 364 XXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNP 543 QN L E+ +G +L EL ++ N + LP S+G L KL + N Sbjct: 266 KQLSILKVDQN--RLCEVTEAIGDCENLSELILTENLLMALPRSLGKLTKLTNLNVDRNH 323 Query: 544 LICPPMDI 567 L P +I Sbjct: 324 LEALPPEI 331 Score = 80.9 bits (198), Expect = 2e-15 Identities = 58/187 (31%), Positives = 90/187 (48%), Gaps = 1/187 (0%) Frame = +1 Query: 10 RLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQ 189 RLLN+ L + N+++ LP + +L L+VS N + +P +I+ C+ALE + + N Sbjct: 57 RLLNLRKLGLSDNEIQRLPPEVANFMQLVELDVSRNDIPEIPESIKFCKALEIADFSGNP 116 Query: 190 LTRLPDTLGF-ELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXX 366 L+RLPD GF +L SL L++N L +LP ++ L L+ R N Sbjct: 117 LSRLPD--GFTQLRSLAHLALNDVSLQALPGDVGNLANLVTLELREN------------- 161 Query: 367 XXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPL 546 L+ LP L L L +LD+ N + VLPD++G L L + N L Sbjct: 162 ------------LLKSLPASLSFLVKLEQLDLGGNDLEVLPDTLGALPNLRELWLDRNQL 209 Query: 547 ICPPMDI 567 P ++ Sbjct: 210 SALPPEL 216 Score = 80.5 bits (197), Expect = 3e-15 Identities = 58/189 (30%), Positives = 92/189 (48%) Frame = +1 Query: 1 GIARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNAN 180 G +L ++ L + L++LP +G L+ L L + NLL+SLPA++ LE+L+ Sbjct: 123 GFTQLRSLAHLALNDVSLQALPGDVGNLANLVTLELRENLLKSLPASLSFLVKLEQLDLG 182 Query: 181 FNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXX 360 N L LPDTLG L +LR L ++ N+L++LP ++ L LD N + Sbjct: 183 GNDLEVLPDTLG-ALPNLRELWLDRNQLSALPPELGNLRRLVCLDVSENRLEELPAELGG 241 Query: 361 XXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGN 540 SQN LR LP G+G L L L + N + + +++G L++ N Sbjct: 242 LVLLTDLLLSQN--LLRRLPDGIGQLKQLSILKVDQNRLCEVTEAIGDCENLSELILTEN 299 Query: 541 PLICPPMDI 567 L+ P + Sbjct: 300 LLMALPRSL 308 Score = 68.6 bits (166), Expect = 1e-11 Identities = 55/171 (32%), Positives = 73/171 (42%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 +A + +V LDV N + +P SI L + + SGN L LP + R+L L N Sbjct: 78 VANFMQLVELDVSRNDIPEIPESIKFCKALEIADFSGNPLSRLPDGFTQLRSLAHLALND 137 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXX 363 L LP +G L +L L + N L SLP S S + L LD N Sbjct: 138 VSLQALPGDVG-NLANLVTLELRENLLKSLPASLSFLVKLEQLDLGGN------------ 184 Query: 364 XXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKL 516 L LP LG L +LREL + N +S LP +G L +L Sbjct: 185 -------------DLEVLPDTLGALPNLRELWLDRNQLSALPPELGNLRRL 222 Score = 60.5 bits (145), Expect = 3e-09 Identities = 43/100 (43%), Positives = 57/100 (57%), Gaps = 2/100 (2%) Frame = +1 Query: 19 NVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTR 198 N+ L + N L +LP S+G L+KL LNV N L++LP I C AL L+ N+L Sbjct: 290 NLSELILTENLLMALPRSLGKLTKLTNLNVDRNHLEALPPEIGGCVALSVLSLRDNRLAV 349 Query: 199 LPDTLGF--ELHSLRRLSVNSNKLTSLPFSTSHMTALRAL 312 LP L ELH L V N+L SLPF+ +H+ L+AL Sbjct: 350 LPPELAHTTELHV---LDVAGNRLQSLPFALTHLN-LKAL 385 Score = 55.8 bits (133), Expect = 8e-08 Identities = 37/113 (32%), Positives = 58/113 (51%) Frame = +1 Query: 1 GIARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNAN 180 GI +L + +L V N+L + +IG L L ++ NLL +LP ++ + L LN + Sbjct: 261 GIGQLKQLSILKVDQNRLCEVTEAIGDCENLSELILTENLLMALPRSLGKLTKLTNLNVD 320 Query: 181 FNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRA 339 N L LP +G +L LS+ N+L LP +H T L LD N +++ Sbjct: 321 RNHLEALPPEIG-GCVALSVLSLRDNRLAVLPPELAHTTELHVLDVAGNRLQS 372 Score = 48.9 bits (115), Expect = 1e-05 Identities = 44/133 (33%), Positives = 60/133 (45%), Gaps = 1/133 (0%) Frame = +1 Query: 121 LQSLPATIEE-CRALEELNANFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMT 297 LQ++P I R+LEEL + NQL LP F L +LR+L ++ N++ LP ++ Sbjct: 24 LQAVPEEIYRYSRSLEELLLDANQLRELPKPF-FRLLNLRKLGLSDNEIQRLPPEVANFM 82 Query: 298 ALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSI 477 L LD N I S N L LP G L SL L ++ S+ Sbjct: 83 QLVELDVSRNDIPEIPESIKFCKALEIADFSGN--PLSRLPDGFTQLRSLAHLALNDVSL 140 Query: 478 SVLPDSMGCLAKL 516 LP +G LA L Sbjct: 141 QALPGDVGNLANL 153
>LAP4_MOUSE (Q80U72) LAP4 protein (Scribble homolog protein)| Length = 1612 Score = 80.9 bits (198), Expect = 2e-15 Identities = 63/186 (33%), Positives = 89/186 (47%), Gaps = 1/186 (0%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 + L N+V L++R N LKSLP S+ L KL L++ GN L+ LP T+ L EL + Sbjct: 147 VGNLANLVTLELRENLLKSLPASLSFLVKLEQLDLGGNDLEVLPDTLGALPNLRELWLDR 206 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXX 363 NQL+ LP LG L L L V+ N+L LP + L L N ++ Sbjct: 207 NQLSALPPELG-NLRRLVCLDVSENRLEELPVELGGLALLTDLLLSQNLLQRLPEGIGQL 265 Query: 364 XXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNP 543 QN L E+ +G +L EL ++ N ++ LP S+G L KL + N Sbjct: 266 KQLSILKVDQN--RLCEVTEAIGDCENLSELILTENLLTALPHSLGKLTKLTNLNVDRNH 323 Query: 544 L-ICPP 558 L + PP Sbjct: 324 LEVLPP 329 Score = 80.9 bits (198), Expect = 2e-15 Identities = 58/187 (31%), Positives = 90/187 (48%), Gaps = 1/187 (0%) Frame = +1 Query: 10 RLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQ 189 RLLN+ L + N+++ LP + +L L+VS N + +P +I+ C+ALE + + N Sbjct: 57 RLLNLRKLGLSDNEIQRLPPEVANFMQLVELDVSRNDIPEIPESIKFCKALEIADFSGNP 116 Query: 190 LTRLPDTLGF-ELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXX 366 L+RLPD GF +L SL L++N L +LP ++ L L+ R N Sbjct: 117 LSRLPD--GFTQLRSLAHLALNDVSLQALPGDVGNLANLVTLELREN------------- 161 Query: 367 XXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPL 546 L+ LP L L L +LD+ N + VLPD++G L L + N L Sbjct: 162 ------------LLKSLPASLSFLVKLEQLDLGGNDLEVLPDTLGALPNLRELWLDRNQL 209 Query: 547 ICPPMDI 567 P ++ Sbjct: 210 SALPPEL 216 Score = 78.2 bits (191), Expect = 2e-14 Identities = 57/186 (30%), Positives = 90/186 (48%) Frame = +1 Query: 1 GIARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNAN 180 G +L ++ L + L++LP +G L+ L L + NLL+SLPA++ LE+L+ Sbjct: 123 GFTQLRSLAHLALNDVSLQALPGDVGNLANLVTLELRENLLKSLPASLSFLVKLEQLDLG 182 Query: 181 FNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXX 360 N L LPDTLG L +LR L ++ N+L++LP ++ L LD N + Sbjct: 183 GNDLEVLPDTLG-ALPNLRELWLDRNQLSALPPELGNLRRLVCLDVSENRLEELPVELGG 241 Query: 361 XXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGN 540 SQN L+ LP G+G L L L + N + + +++G L++ N Sbjct: 242 LALLTDLLLSQN--LLQRLPEGIGQLKQLSILKVDQNRLCEVTEAIGDCENLSELILTEN 299 Query: 541 PLICPP 558 L P Sbjct: 300 LLTALP 305 Score = 68.6 bits (166), Expect = 1e-11 Identities = 55/171 (32%), Positives = 73/171 (42%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 +A + +V LDV N + +P SI L + + SGN L LP + R+L L N Sbjct: 78 VANFMQLVELDVSRNDIPEIPESIKFCKALEIADFSGNPLSRLPDGFTQLRSLAHLALND 137 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXX 363 L LP +G L +L L + N L SLP S S + L LD N Sbjct: 138 VSLQALPGDVG-NLANLVTLELRENLLKSLPASLSFLVKLEQLDLGGN------------ 184 Query: 364 XXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKL 516 L LP LG L +LREL + N +S LP +G L +L Sbjct: 185 -------------DLEVLPDTLGALPNLRELWLDRNQLSALPPELGNLRRL 222 Score = 59.7 bits (143), Expect = 6e-09 Identities = 43/100 (43%), Positives = 57/100 (57%), Gaps = 2/100 (2%) Frame = +1 Query: 19 NVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTR 198 N+ L + N L +LP+S+G L+KL LNV N L+ LP I C AL L+ N+L Sbjct: 290 NLSELILTENLLTALPHSLGKLTKLTNLNVDRNHLEVLPPEIGGCVALSVLSLRDNRLAV 349 Query: 199 LPDTLGF--ELHSLRRLSVNSNKLTSLPFSTSHMTALRAL 312 LP L ELH L V N+L SLPF+ +H+ L+AL Sbjct: 350 LPPELAHTAELHV---LDVAGNRLRSLPFALTHLN-LKAL 385 Score = 53.9 bits (128), Expect = 3e-07 Identities = 37/113 (32%), Positives = 57/113 (50%) Frame = +1 Query: 1 GIARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNAN 180 GI +L + +L V N+L + +IG L L ++ NLL +LP ++ + L LN + Sbjct: 261 GIGQLKQLSILKVDQNRLCEVTEAIGDCENLSELILTENLLTALPHSLGKLTKLTNLNVD 320 Query: 181 FNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRA 339 N L LP +G +L LS+ N+L LP +H L LD N +R+ Sbjct: 321 RNHLEVLPPEIG-GCVALSVLSLRDNRLAVLPPELAHTAELHVLDVAGNRLRS 372 Score = 47.8 bits (112), Expect = 2e-05 Identities = 44/133 (33%), Positives = 59/133 (44%), Gaps = 1/133 (0%) Frame = +1 Query: 121 LQSLPATIEE-CRALEELNANFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMT 297 LQ +P I R+LEEL + NQL LP F L +LR+L ++ N++ LP ++ Sbjct: 24 LQVVPEEIYRYSRSLEELLLDANQLRELPKPF-FRLLNLRKLGLSDNEIQRLPPEVANFM 82 Query: 298 ALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSI 477 L LD N I S N L LP G L SL L ++ S+ Sbjct: 83 QLVELDVSRNDIPEIPESIKFCKALEIADFSGN--PLSRLPDGFTQLRSLAHLALNDVSL 140 Query: 478 SVLPDSMGCLAKL 516 LP +G LA L Sbjct: 141 QALPGDVGNLANL 153
>SHOC2_MOUSE (O88520) Leucine-rich repeat protein SHOC-2 (Ras-binding protein| Sur-8) Length = 582 Score = 80.5 bits (197), Expect = 3e-15 Identities = 54/190 (28%), Positives = 90/190 (47%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 + L + L + SN+L+SLP +GCL L L +S N L SLP +++ + L L+ Sbjct: 119 VKELTQLTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDSLDNLKKLRMLDLRH 178 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXX 363 N+L +P + + L SL L + N++T++ ++ L L R N I+ Sbjct: 179 NKLREIPSVV-YRLDSLTTLYLRFNRITTVEKDIKNLPKLSMLSIRENKIKQLPAEIGEL 237 Query: 364 XXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNP 543 + N L LP +G T + LD+ +N + LPD++G L+ LN+ N Sbjct: 238 CNLITLDVAHN--QLEHLPKEIGNCTQITNLDLQHNDLLDLPDTIGNLSSLNRLGLRYNR 295 Query: 544 LICPPMDIVE 573 L P + + Sbjct: 296 LSAIPRSLAK 305 Score = 79.3 bits (194), Expect = 7e-15 Identities = 64/236 (27%), Positives = 96/236 (40%), Gaps = 48/236 (20%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 I + LD++ N L LP++IG LS L L + N L ++P ++ +C ALEELN Sbjct: 257 IGNCTQITNLDLQHNDLLDLPDTIGNLSSLNRLGLRYNRLSAIPRSLAKCSALEELNLEN 316 Query: 184 NQLTRLPDTL---------------GFELHS----------------------------- 231 N ++ LP++L F+L+ Sbjct: 317 NNISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFS 376 Query: 232 ----LRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNF 399 L +L++ N+LTSLP T++ L+ N + S N Sbjct: 377 RAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNN- 435 Query: 400 HFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPLICPPMDI 567 L++LP+GLG L LRELD+ N + LP+ + L L K N L P I Sbjct: 436 -LLKKLPHGLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLSTLPRGI 490 Score = 75.1 bits (183), Expect = 1e-13 Identities = 56/188 (29%), Positives = 87/188 (46%), Gaps = 1/188 (0%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 I L + +L +R N++K LP IG L L L+V+ N L+ LP I C + L+ Sbjct: 211 IKNLPKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQH 270 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXX 363 N L LPDT+G L SL RL + N+L+++P S + +AL L+ N I Sbjct: 271 NDLLDLPDTIG-NLSSLNRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPESLLSS 329 Query: 364 XXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAK-LNKFSAVGN 540 F G +++ L++ +N I+ +P + AK L+K + N Sbjct: 330 LVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDN 389 Query: 541 PLICPPMD 564 L P+D Sbjct: 390 QLTSLPLD 397 Score = 73.2 bits (178), Expect = 5e-13 Identities = 51/186 (27%), Positives = 86/186 (46%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQL 192 L+N++ L + N L SLP+S+ L KLR+L++ N L+ +P+ + +L L FN++ Sbjct: 145 LVNLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRI 204 Query: 193 TRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXX 372 T + + L L LS+ NK+ LP + L LD N + Sbjct: 205 TTVEKDIK-NLPKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQI 263 Query: 373 XXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPLIC 552 N L +LP +G L+SL L + YN +S +P S+ + L + + N + Sbjct: 264 TNLDLQHND--LLDLPDTIGNLSSLNRLGLRYNRLSAIPRSLAKCSALEELNLENNNIST 321 Query: 553 PPMDIV 570 P ++ Sbjct: 322 LPESLL 327 Score = 68.9 bits (167), Expect = 9e-12 Identities = 55/185 (29%), Positives = 87/185 (47%), Gaps = 1/185 (0%) Frame = +1 Query: 19 NVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTR 198 ++V L++ +NQL +P + L L VL +S NLL+ LP + R L EL+ N+L Sbjct: 403 SMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLES 462 Query: 199 LPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXX 378 LP+ + + L L++L + +N+L++LP H+T L L N Sbjct: 463 LPNEIAY-LKDLQKLVLTNNQLSTLPRGIGHLTNLTHLGLGEN----------------- 504 Query: 379 XXXSQNFHFLRELPYGLGLLTSLRELDISYN-SISVLPDSMGCLAKLNKFSAVGNPLICP 555 L LP +G L +L EL ++ N ++ LP + +KL+ S PL Sbjct: 505 --------LLTHLPEEIGTLENLEELYLNDNPNLHSLPFELALCSKLSIMSIENCPLSHL 556 Query: 556 PMDIV 570 P IV Sbjct: 557 PPQIV 561 Score = 67.8 bits (164), Expect = 2e-11 Identities = 52/171 (30%), Positives = 77/171 (45%) Frame = +1 Query: 31 LDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDT 210 L+++ NQL SLP G + + LN++ N L +P + +LE L + N L +LP Sbjct: 384 LNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHG 443 Query: 211 LGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXS 390 LG L LR L + NKL SLP +++ L+ L N Sbjct: 444 LG-NLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNN--------------------- 481 Query: 391 QNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNP 543 L LP G+G LT+L L + N ++ LP+ +G L L + NP Sbjct: 482 ----QLSTLPRGIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDNP 528 Score = 67.8 bits (164), Expect = 2e-11 Identities = 53/180 (29%), Positives = 81/180 (45%) Frame = +1 Query: 19 NVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTR 198 N + LD+ + LP S+ L++L L + N LQSLPA + L L + N LT Sbjct: 101 NSMRLDLSKRSIHILPPSVKELTQLTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTS 160 Query: 199 LPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXX 378 LPD+L L LR L + NKL +P + +L L R N I Sbjct: 161 LPDSLD-NLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLPKLSM 219 Query: 379 XXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPLICPP 558 +N +++LP +G L +L LD+++N + LP +G ++ N L+ P Sbjct: 220 LSIREN--KIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQHNDLLDLP 277 Score = 58.5 bits (140), Expect = 1e-08 Identities = 36/91 (39%), Positives = 55/91 (60%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 ++ L+++ VL + +N LK LP+ +G L KLR L++ N L+SLP I + L++L Sbjct: 421 VSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTN 480 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTSLP 276 NQL+ LP +G L +L L + N LT LP Sbjct: 481 NQLSTLPRGIG-HLTNLTHLGLGENLLTHLP 510 Score = 57.0 bits (136), Expect = 4e-08 Identities = 40/111 (36%), Positives = 56/111 (50%), Gaps = 1/111 (0%) Frame = +1 Query: 1 GIARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNAN 180 G+ L + LD+ N+L+SLPN I L L+ L ++ N L +LP I L L Sbjct: 443 GLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLSTLPRGIGHLTNLTHLGLG 502 Query: 181 FNQLTRLPDTLGFELHSLRRLSVNSN-KLTSLPFSTSHMTALRALDARLNC 330 N LT LP+ +G L +L L +N N L SLPF + + L + NC Sbjct: 503 ENLLTHLPEEIG-TLENLEELYLNDNPNLHSLPFELALCSKLSIMSIE-NC 551
>SHOC2_HUMAN (Q9UQ13) Leucine-rich repeat protein SHOC-2 (Ras-binding protein| Sur-8) Length = 582 Score = 80.1 bits (196), Expect = 4e-15 Identities = 64/236 (27%), Positives = 97/236 (41%), Gaps = 48/236 (20%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 I + LD++ N+L LP++IG LS L L + N L ++P ++ +C ALEELN Sbjct: 257 IGNCTQITNLDLQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLEN 316 Query: 184 NQLTRLPDTL---------------GFELHS----------------------------- 231 N ++ LP++L F+L+ Sbjct: 317 NNISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFS 376 Query: 232 ----LRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNF 399 L +L++ N+LTSLP T++ L+ N + S N Sbjct: 377 RAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNN- 435 Query: 400 HFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPLICPPMDI 567 L++LP+GLG L LRELD+ N + LP+ + L L K N L P I Sbjct: 436 -LLKKLPHGLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLTTLPRGI 490 Score = 79.7 bits (195), Expect = 5e-15 Identities = 54/190 (28%), Positives = 91/190 (47%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 I L + L + SN+L+SLP +GCL L L +S N L SLP +++ + L L+ Sbjct: 119 IKELTQLTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDSLDNLKKLRMLDLRH 178 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXX 363 N+L +P + + L SL L + N++T++ +++ L L R N I+ Sbjct: 179 NKLREIPSVV-YRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAEIGEL 237 Query: 364 XXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNP 543 + N L LP +G T + LD+ +N + LPD++G L+ L++ N Sbjct: 238 CNLITLDVAHN--QLEHLPKEIGNCTQITNLDLQHNELLDLPDTIGNLSSLSRLGLRYNR 295 Query: 544 LICPPMDIVE 573 L P + + Sbjct: 296 LSAIPRSLAK 305 Score = 75.9 bits (185), Expect = 8e-14 Identities = 56/188 (29%), Positives = 88/188 (46%), Gaps = 1/188 (0%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 I L + +L +R N++K LP IG L L L+V+ N L+ LP I C + L+ Sbjct: 211 IKNLSKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQH 270 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXX 363 N+L LPDT+G L SL RL + N+L+++P S + +AL L+ N I Sbjct: 271 NELLDLPDTIG-NLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPESLLSS 329 Query: 364 XXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAK-LNKFSAVGN 540 F G +++ L++ +N I+ +P + AK L+K + N Sbjct: 330 LVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDN 389 Query: 541 PLICPPMD 564 L P+D Sbjct: 390 QLTSLPLD 397 Score = 73.2 bits (178), Expect = 5e-13 Identities = 51/186 (27%), Positives = 86/186 (46%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQL 192 L+N++ L + N L SLP+S+ L KLR+L++ N L+ +P+ + +L L FN++ Sbjct: 145 LVNLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRI 204 Query: 193 TRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXX 372 T + + L L LS+ NK+ LP + L LD N + Sbjct: 205 TTVEKDIK-NLSKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQI 263 Query: 373 XXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPLIC 552 N L +LP +G L+SL L + YN +S +P S+ + L + + N + Sbjct: 264 TNLDLQHNE--LLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNIST 321 Query: 553 PPMDIV 570 P ++ Sbjct: 322 LPESLL 327 Score = 70.5 bits (171), Expect = 3e-12 Identities = 56/185 (30%), Positives = 87/185 (47%), Gaps = 1/185 (0%) Frame = +1 Query: 19 NVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTR 198 ++V L++ +NQL +P + L L VL +S NLL+ LP + R L EL+ N+L Sbjct: 403 SMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLES 462 Query: 199 LPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXX 378 LP+ + + L L++L + +N+LT+LP H+T L L N Sbjct: 463 LPNEIAY-LKDLQKLVLTNNQLTTLPRGIGHLTNLTHLGLGEN----------------- 504 Query: 379 XXXSQNFHFLRELPYGLGLLTSLRELDISYN-SISVLPDSMGCLAKLNKFSAVGNPLICP 555 L LP +G L +L EL ++ N ++ LP + +KL+ S PL Sbjct: 505 --------LLTHLPEEIGTLENLEELYLNDNPNLHSLPFELALCSKLSIMSIENCPLSHL 556 Query: 556 PMDIV 570 P IV Sbjct: 557 PPQIV 561 Score = 70.1 bits (170), Expect = 4e-12 Identities = 54/180 (30%), Positives = 82/180 (45%) Frame = +1 Query: 19 NVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTR 198 N + LD+ + LP+SI L++L L + N LQSLPA + L L + N LT Sbjct: 101 NSMRLDLSKRSIHILPSSIKELTQLTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTS 160 Query: 199 LPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXX 378 LPD+L L LR L + NKL +P + +L L R N I Sbjct: 161 LPDSLD-NLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSM 219 Query: 379 XXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPLICPP 558 +N +++LP +G L +L LD+++N + LP +G ++ N L+ P Sbjct: 220 LSIREN--KIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQHNELLDLP 277 Score = 67.8 bits (164), Expect = 2e-11 Identities = 52/171 (30%), Positives = 77/171 (45%) Frame = +1 Query: 31 LDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDT 210 L+++ NQL SLP G + + LN++ N L +P + +LE L + N L +LP Sbjct: 384 LNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHG 443 Query: 211 LGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXS 390 LG L LR L + NKL SLP +++ L+ L N Sbjct: 444 LG-NLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNN--------------------- 481 Query: 391 QNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNP 543 L LP G+G LT+L L + N ++ LP+ +G L L + NP Sbjct: 482 ----QLTTLPRGIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDNP 528 Score = 60.1 bits (144), Expect = 4e-09 Identities = 37/91 (40%), Positives = 55/91 (60%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 ++ L+++ VL + +N LK LP+ +G L KLR L++ N L+SLP I + L++L Sbjct: 421 VSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTN 480 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTSLP 276 NQLT LP +G L +L L + N LT LP Sbjct: 481 NQLTTLPRGIG-HLTNLTHLGLGENLLTHLP 510 Score = 56.6 bits (135), Expect = 5e-08 Identities = 40/111 (36%), Positives = 56/111 (50%), Gaps = 1/111 (0%) Frame = +1 Query: 1 GIARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNAN 180 G+ L + LD+ N+L+SLPN I L L+ L ++ N L +LP I L L Sbjct: 443 GLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTHLGLG 502 Query: 181 FNQLTRLPDTLGFELHSLRRLSVNSN-KLTSLPFSTSHMTALRALDARLNC 330 N LT LP+ +G L +L L +N N L SLPF + + L + NC Sbjct: 503 ENLLTHLPEEIG-TLENLEELYLNDNPNLHSLPFELALCSKLSIMSIE-NC 551
>LAP2_MOUSE (Q80TH2) LAP2 protein (Erbb2-interacting protein) (Erbin)| (Densin-180-like protein) Length = 1402 Score = 79.0 bits (193), Expect = 9e-15 Identities = 62/210 (29%), Positives = 92/210 (43%), Gaps = 21/210 (10%) Frame = +1 Query: 1 GIARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNAN 180 G ++LLN+ L + L+ LP + G L+KL++L + N L+ LP T+ LE L+ Sbjct: 133 GFSQLLNLTQLYLNDAFLEFLPANFGRLTKLQILELRENQLKMLPKTMNRLTQLERLDLG 192 Query: 181 FNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXX 360 N+ T +P+ L +L LR ++ N+LT +P + L LD N I Sbjct: 193 SNEFTEVPEVLE-QLSGLREFWMDGNRLTFIPGFIGSLRQLTYLDVSKNNIEMVEEGIST 251 Query: 361 XXXXXXXXXSQNF---------------------HFLRELPYGLGLLTSLRELDISYNSI 477 S N + L LP +G L S+ ELD S+N I Sbjct: 252 CENPQDFLLSSNSLQQLPETIGSLKNVTTLKIDENQLMYLPDSIGGLRSIEELDCSFNEI 311 Query: 478 SVLPDSMGCLAKLNKFSAVGNPLICPPMDI 567 LP S+G L + F+A N L P +I Sbjct: 312 EALPSSIGQLTNMRTFAADHNYLQQLPPEI 341 Score = 63.5 bits (153), Expect = 4e-10 Identities = 58/234 (24%), Positives = 89/234 (38%), Gaps = 46/234 (19%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSI------------------------------------ 75 IA L+N+ LDV N ++ P +I Sbjct: 88 IANLINLRELDVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLND 147 Query: 76 ----------GCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDTLGFEL 225 G L+KL++L + N L+ LP T+ LE L+ N+ T +P+ L +L Sbjct: 148 AFLEFLPANFGRLTKLQILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLE-QL 206 Query: 226 HSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHF 405 LR ++ N+LT +P + L LD N I S N Sbjct: 207 SGLREFWMDGNRLTFIPGFIGSLRQLTYLDVSKNNIEMVEEGISTCENPQDFLLSSN--S 264 Query: 406 LRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPLICPPMDI 567 L++LP +G L ++ L I N + LPDS+G L + + N + P I Sbjct: 265 LQQLPETIGSLKNVTTLKIDENQLMYLPDSIGGLRSIEELDCSFNEIEALPSSI 318 Score = 62.4 bits (150), Expect = 9e-10 Identities = 47/181 (25%), Positives = 78/181 (43%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 I L + LDV N ++ + I + +S N LQ LP TI + + L + Sbjct: 226 IGSLRQLTYLDVSKNNIEMVEEGISTCENPQDFLLSSNSLQQLPETIGSLKNVTTLKIDE 285 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXX 363 NQL LPD++G L S+ L + N++ +LP S +T +R A Sbjct: 286 NQLMYLPDSIG-GLRSIEELDCSFNEIEALPSSIGQLTNMRTFAA--------------- 329 Query: 364 XXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNP 543 + ++L++LP +G ++ L + N + LP+ MG + KL + N Sbjct: 330 ----------DHNYLQQLPPEIGNWKNITVLFLHCNKLETLPEEMGDMQKLKVINLSDNR 379 Query: 544 L 546 L Sbjct: 380 L 380 Score = 58.9 bits (141), Expect = 1e-08 Identities = 47/172 (27%), Positives = 79/172 (45%) Frame = +1 Query: 1 GIARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNAN 180 GI+ N + SN L+ LP +IG L + L + N L LP +I R++EEL+ + Sbjct: 248 GISTCENPQDFLLSSNSLQQLPETIGSLKNVTTLKIDENQLMYLPDSIGGLRSIEELDCS 307 Query: 181 FNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXX 360 FN++ LP ++G +L ++R + + N L LP + + L L+C + Sbjct: 308 FNEIEALPSSIG-QLTNMRTFAADHNYLQQLPPEIGNWKNITVL--FLHCNK-------- 356 Query: 361 XXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKL 516 L LP +G + L+ +++S N + LP S L +L Sbjct: 357 ---------------LETLPEEMGDMQKLKVINLSDNRLKNLPFSFTKLQQL 393 Score = 57.8 bits (138), Expect = 2e-08 Identities = 54/196 (27%), Positives = 83/196 (42%), Gaps = 24/196 (12%) Frame = +1 Query: 43 SNQLKSLPN-----------------------SIGCLSKLRVLNVSGNLLQSLPATIEEC 153 +NQ++ LP SI L LR L+VS N +Q P I+ C Sbjct: 55 ANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANLINLRELDVSKNGIQEFPENIKNC 114 Query: 154 RALEELNANFNQLTRLPDTLGF-ELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNC 330 + L + A+ N +++LPD GF +L +L +L +N L LP + +T L+ L+ R N Sbjct: 115 KVLTIVEASVNPISKLPD--GFSQLLNLTQLYLNDAFLEFLPANFGRLTKLQILELREN- 171 Query: 331 IRAXXXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLA 510 L+ LP + LT L LD+ N + +P+ + L+ Sbjct: 172 ------------------------QLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLS 207 Query: 511 KLNKFSAVGNPLICPP 558 L +F GN L P Sbjct: 208 GLREFWMDGNRLTFIP 223 Score = 53.5 bits (127), Expect = 4e-07 Identities = 44/150 (29%), Positives = 62/150 (41%), Gaps = 21/150 (14%) Frame = +1 Query: 154 RALEELNANFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCI 333 + LEEL + NQ+ LP L F SL +LS+ N LT+LP S +++ LR LD N I Sbjct: 46 KTLEELYLDANQIEELPKQL-FNCQSLHKLSLPDNDLTTLPASIANLINLRELDVSKNGI 104 Query: 334 RAXXXXXXXXXXXXXXXXS---------------------QNFHFLRELPYGLGLLTSLR 450 + S N FL LP G LT L+ Sbjct: 105 QEFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANFGRLTKLQ 164 Query: 451 ELDISYNSISVLPDSMGCLAKLNKFSAVGN 540 L++ N + +LP +M L +L + N Sbjct: 165 ILELRENQLKMLPKTMNRLTQLERLDLGSN 194 Score = 42.4 bits (98), Expect = 0.001 Identities = 20/57 (35%), Positives = 37/57 (64%) Frame = +1 Query: 19 NVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQ 189 N+ VL + N+L++LP +G + KL+V+N+S N L++LP + + + L + + NQ Sbjct: 346 NITVLFLHCNKLETLPEEMGDMQKLKVINLSDNRLKNLPFSFTKLQQLTAMWLSDNQ 402
>LRSM1_HUMAN (Q6UWE0) Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich| repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL) Length = 723 Score = 78.6 bits (192), Expect = 1e-14 Identities = 43/100 (43%), Positives = 61/100 (61%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQL 192 L + VLD+ NQL +LP+ +G L+ L+VLNV N L LP +I L+ LN N+L Sbjct: 80 LATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKL 139 Query: 193 TRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRAL 312 LPDT+G EL SLR L+++ N++ LP +H+ L L Sbjct: 140 KELPDTVG-ELRSLRTLNISGNEIQRLPQMLAHVRTLEML 178 Score = 64.3 bits (155), Expect = 2e-10 Identities = 36/91 (39%), Positives = 56/91 (61%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 + +L + VL+V NQL LP SIG L++L+ LNV N L+ LP T+ E R+L LN + Sbjct: 100 LGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKELPDTVGELRSLRTLNISG 159 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTSLP 276 N++ RLP L + +L LS++++ + P Sbjct: 160 NEIQRLPQMLA-HVRTLEMLSLDASAMVYPP 189 Score = 63.9 bits (154), Expect = 3e-10 Identities = 55/186 (29%), Positives = 87/186 (46%), Gaps = 6/186 (3%) Frame = +1 Query: 28 VLDVRSNQLKSLPNSIGCLSKL---RVLNVSGNLLQSL---PATIEECRALEELNANFNQ 189 +LD+ +L +P K+ +VL V N L SL ++ ++ L+ + NQ Sbjct: 33 ILDISKCELSEIPFGAFATCKVLQKKVLIVHTNHLTSLLPKSCSLLSLATIKVLDLHDNQ 92 Query: 190 LTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXX 369 LT LPD LG +L +L+ L+V N+L LP S ++T L+ L+ + N Sbjct: 93 LTALPDDLG-QLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNK------------- 138 Query: 370 XXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPLI 549 L+ELP +G L SLR L+IS N I LP + + L S + ++ Sbjct: 139 ------------LKELPDTVGELRSLRTLNISGNEIQRLPQMLAHVRTLEMLSLDASAMV 186 Query: 550 CPPMDI 567 PP ++ Sbjct: 187 YPPREV 192 Score = 58.5 bits (140), Expect = 1e-08 Identities = 42/112 (37%), Positives = 63/112 (56%), Gaps = 3/112 (2%) Frame = +1 Query: 10 RLLNVVVLDVRSNQLKSL-PNSIGCLS--KLRVLNVSGNLLQSLPATIEECRALEELNAN 180 ++L VL V +N L SL P S LS ++VL++ N L +LP + + AL+ LN Sbjct: 53 KVLQKKVLIVHTNHLTSLLPKSCSLLSLATIKVLDLHDNQLTALPDDLGQLTALQVLNVE 112 Query: 181 FNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIR 336 NQL +LP ++G L L+ L+V NKL LP + + +LR L+ N I+ Sbjct: 113 RNQLMQLPRSIG-NLTQLQTLNVKDNKLKELPDTVGELRSLRTLNISGNEIQ 163
>LRSM1_MOUSE (Q80ZI6) Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich| repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) Length = 727 Score = 78.6 bits (192), Expect = 1e-14 Identities = 44/100 (44%), Positives = 61/100 (61%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQL 192 L+ + VLD+ NQL +LP+ +G L+ L+VLNV N L LP +I L+ LN N+L Sbjct: 80 LVTIKVLDLHENQLTALPDDMGQLTVLQVLNVERNQLTHLPRSIGNLLQLQTLNVKDNKL 139 Query: 193 TRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRAL 312 LPDTLG EL SLR L ++ N++ LP +H+ L L Sbjct: 140 KELPDTLG-ELRSLRTLDISENEIQRLPQMLAHVRTLETL 178 Score = 62.4 bits (150), Expect = 9e-10 Identities = 56/186 (30%), Positives = 85/186 (45%), Gaps = 6/186 (3%) Frame = +1 Query: 28 VLDVRSNQLKSLPNSIGCLSKL---RVLNVSGNLLQSL---PATIEECRALEELNANFNQ 189 +LD+ +L +P K+ +VL V N L SL ++ ++ L+ + NQ Sbjct: 33 ILDISKCELSEIPFGAFATCKVLQKKVLIVHTNHLTSLLPKSCSLLSLVTIKVLDLHENQ 92 Query: 190 LTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXX 369 LT LPD +G +L L+ L+V N+LT LP S ++ L+ L+ + N Sbjct: 93 LTALPDDMG-QLTVLQVLNVERNQLTHLPRSIGNLLQLQTLNVKDNK------------- 138 Query: 370 XXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPLI 549 L+ELP LG L SLR LDIS N I LP + + L S ++ Sbjct: 139 ------------LKELPDTLGELRSLRTLDISENEIQRLPQMLAHVRTLETLSLNALAMV 186 Query: 550 CPPMDI 567 PP ++ Sbjct: 187 YPPPEV 192 Score = 60.1 bits (144), Expect = 4e-09 Identities = 35/84 (41%), Positives = 52/84 (61%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 + +L + VL+V NQL LP SIG L +L+ LNV N L+ LP T+ E R+L L+ + Sbjct: 100 MGQLTVLQVLNVERNQLTHLPRSIGNLLQLQTLNVKDNKLKELPDTLGELRSLRTLDISE 159 Query: 184 NQLTRLPDTLGFELHSLRRLSVNS 255 N++ RLP L + +L LS+N+ Sbjct: 160 NEIQRLPQMLA-HVRTLETLSLNA 182 Score = 59.7 bits (143), Expect = 6e-09 Identities = 43/112 (38%), Positives = 62/112 (55%), Gaps = 3/112 (2%) Frame = +1 Query: 10 RLLNVVVLDVRSNQLKSL-PNSIGCLS--KLRVLNVSGNLLQSLPATIEECRALEELNAN 180 ++L VL V +N L SL P S LS ++VL++ N L +LP + + L+ LN Sbjct: 53 KVLQKKVLIVHTNHLTSLLPKSCSLLSLVTIKVLDLHENQLTALPDDMGQLTVLQVLNVE 112 Query: 181 FNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIR 336 NQLT LP ++G L L+ L+V NKL LP + + +LR LD N I+ Sbjct: 113 RNQLTHLPRSIG-NLLQLQTLNVKDNKLKELPDTLGELRSLRTLDISENEIQ 163
>LAP2_HUMAN (Q96RT1) LAP2 protein (Erbb2-interacting protein) (Erbin)| (Densin-180-like protein) Length = 1412 Score = 78.6 bits (192), Expect = 1e-14 Identities = 61/210 (29%), Positives = 93/210 (44%), Gaps = 21/210 (10%) Frame = +1 Query: 1 GIARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNAN 180 G ++LLN+ L + L+ LP + G L+KL++L + N L+ LP T+ LE L+ Sbjct: 133 GFSQLLNLTQLYLNDAFLEFLPANFGRLTKLQILELRENQLKMLPKTMNRLTQLERLDLG 192 Query: 181 FNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXX 360 N+ T +P+ L +L L+ +++N+LT +P + L LD N I Sbjct: 193 SNEFTEVPEVLE-QLSGLKEFWMDANRLTFIPGFIGSLKQLTYLDVSKNNIEMVEEGIST 251 Query: 361 XXXXXXXXXSQNF---------------------HFLRELPYGLGLLTSLRELDISYNSI 477 S N + L LP +G L S+ ELD S+N + Sbjct: 252 CENLQDLLLSSNSLQQLPETIGSLKNITTLKIDENQLMYLPDSIGGLISVEELDCSFNEV 311 Query: 478 SVLPDSMGCLAKLNKFSAVGNPLICPPMDI 567 LP S+G L L F+A N L P +I Sbjct: 312 EALPSSIGQLTNLRTFAADHNYLQQLPPEI 341 Score = 73.6 bits (179), Expect = 4e-13 Identities = 47/168 (27%), Positives = 81/168 (48%) Frame = +1 Query: 43 SNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDTLGFE 222 +N+L +P IG L +L L+VS N ++ + I C L++L + N L +LP+T+G Sbjct: 216 ANRLTFIPGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSNSLQQLPETIG-S 274 Query: 223 LHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFH 402 L ++ L ++ N+L LP S + ++ LD N + A N Sbjct: 275 LKNITTLKIDENQLMYLPDSIGGLISVEELDCSFNEVEALPSSIGQLTNLRTFAADHN-- 332 Query: 403 FLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPL 546 +L++LP +G ++ L + N + LP+ MG + KL + N L Sbjct: 333 YLQQLPPEIGSWKNITVLFLHSNKLETLPEEMGDMQKLKVINLSDNRL 380 Score = 62.0 bits (149), Expect = 1e-09 Identities = 35/103 (33%), Positives = 61/103 (59%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 I L++V LD N++++LP+SIG L+ LR N LQ LP I + + L + Sbjct: 295 IGGLISVEELDCSFNEVEALPSSIGQLTNLRTFAADHNYLQQLPPEIGSWKNITVLFLHS 354 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRAL 312 N+L LP+ +G ++ L+ ++++ N+L +LPFS + + L A+ Sbjct: 355 NKLETLPEEMG-DMQKLKVINLSDNRLKNLPFSFTKLQQLTAM 396 Score = 57.0 bits (136), Expect = 4e-08 Identities = 36/111 (32%), Positives = 60/111 (54%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 I L N+ L + NQL LP+SIG L + L+ S N +++LP++I + L A+ Sbjct: 272 IGSLKNITTLKIDENQLMYLPDSIGGLISVEELDCSFNEVEALPSSIGQLTNLRTFAADH 331 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIR 336 N L +LP +G ++ L ++SNKL +LP M L+ ++ N ++ Sbjct: 332 NYLQQLPPEIG-SWKNITVLFLHSNKLETLPEEMGDMQKLKVINLSDNRLK 381 Score = 55.5 bits (132), Expect = 1e-07 Identities = 53/196 (27%), Positives = 82/196 (41%), Gaps = 24/196 (12%) Frame = +1 Query: 43 SNQLKSLPN-----------------------SIGCLSKLRVLNVSGNLLQSLPATIEEC 153 +NQ++ LP SI L LR L+VS N +Q P I+ C Sbjct: 55 ANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANLINLRELDVSKNGIQEFPENIKNC 114 Query: 154 RALEELNANFNQLTRLPDTLGF-ELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNC 330 + L + A+ N +++LPD GF +L +L +L +N L LP + +T L+ L+ R N Sbjct: 115 KVLTIVEASVNPISKLPD--GFSQLLNLTQLYLNDAFLEFLPANFGRLTKLQILELREN- 171 Query: 331 IRAXXXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLA 510 L+ LP + LT L LD+ N + +P+ + L+ Sbjct: 172 ------------------------QLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLS 207 Query: 511 KLNKFSAVGNPLICPP 558 L +F N L P Sbjct: 208 GLKEFWMDANRLTFIP 223 Score = 53.5 bits (127), Expect = 4e-07 Identities = 44/150 (29%), Positives = 62/150 (41%), Gaps = 21/150 (14%) Frame = +1 Query: 154 RALEELNANFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCI 333 + LEEL + NQ+ LP L F SL +LS+ N LT+LP S +++ LR LD N I Sbjct: 46 KTLEELYLDANQIEELPKQL-FNCQSLHKLSLPDNDLTTLPASIANLINLRELDVSKNGI 104 Query: 334 RAXXXXXXXXXXXXXXXXS---------------------QNFHFLRELPYGLGLLTSLR 450 + S N FL LP G LT L+ Sbjct: 105 QEFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANFGRLTKLQ 164 Query: 451 ELDISYNSISVLPDSMGCLAKLNKFSAVGN 540 L++ N + +LP +M L +L + N Sbjct: 165 ILELRENQLKMLPKTMNRLTQLERLDLGSN 194 Score = 44.3 bits (103), Expect = 2e-04 Identities = 21/57 (36%), Positives = 38/57 (66%) Frame = +1 Query: 19 NVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQ 189 N+ VL + SN+L++LP +G + KL+V+N+S N L++LP + + + L + + NQ Sbjct: 346 NITVLFLHSNKLETLPEEMGDMQKLKVINLSDNRLKNLPFSFTKLQQLTAMWLSDNQ 402
>LAP4_DROME (Q7KRY7) Protein lap4 (Protein scribble) (Protein smell-impaired)| Length = 1851 Score = 77.8 bits (190), Expect = 2e-14 Identities = 65/212 (30%), Positives = 93/212 (43%), Gaps = 23/212 (10%) Frame = +1 Query: 1 GIARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECR-------- 156 G ++L N+ VL + L +LP G L++L L + NLL+ LP TI + Sbjct: 124 GFSQLKNLTVLGLNDMSLTTLPADFGSLTQLESLELRENLLKHLPETISQLTKLKRLDLG 183 Query: 157 ---------------ALEELNANFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSH 291 L EL + NQL RLP LG L L L V+ N+L LP S Sbjct: 184 DNEIEDLPPYLGYLPGLHELWLDHNQLQRLPPELGL-LTKLTYLDVSENRLEELPNEISG 242 Query: 292 MTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYN 471 + +L LD N + A QN L+ L LG +++EL ++ N Sbjct: 243 LVSLTDLDLAQNLLEALPDGIAKLSRLTILKLDQN--RLQRLNDTLGNCENMQELILTEN 300 Query: 472 SISVLPDSMGCLAKLNKFSAVGNPLICPPMDI 567 +S LP S+G + KLN + N L P++I Sbjct: 301 FLSELPASIGQMTKLNNLNVDRNALEYLPLEI 332 Score = 73.6 bits (179), Expect = 4e-13 Identities = 55/162 (33%), Positives = 78/162 (48%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQL 192 L + LDV N+L+ LPN I L L L+++ NLL++LP I + L L + N+L Sbjct: 220 LTKLTYLDVSENRLEELPNEISGLVSLTDLDLAQNLLEALPDGIAKLSRLTILKLDQNRL 279 Query: 193 TRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXX 372 RL DTLG +++ L + N L+ LP S MT L L+ N + Sbjct: 280 QRLNDTLG-NCENMQELILTENFLSELPASIGQMTKLNNLNVDRNALEYLPLEIGQCANL 338 Query: 373 XXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSM 498 N L++LP LG T L LD+S N + LP S+ Sbjct: 339 GVLSLRDN--KLKKLPPELGNCTVLHVLDVSGNQLLYLPYSL 378 Score = 72.8 bits (177), Expect = 7e-13 Identities = 59/185 (31%), Positives = 79/185 (42%) Frame = +1 Query: 19 NVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTR 198 N+V LDV N + +P+ I L L+V + S N + LP+ + + L L N LT Sbjct: 84 NLVELDVSRNDIPDIPDDIKHLQSLQVADFSSNPIPKLPSGFSQLKNLTVLGLNDMSLTT 143 Query: 199 LPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXX 378 LP G L L L + N L LP + S +T L+ LD N I Sbjct: 144 LPADFG-SLTQLESLELRENLLKHLPETISQLTKLKRLDLGDNEIEDLPPYLGYLPGLHE 202 Query: 379 XXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPLICPP 558 N L+ LP LGLLT L LD+S N + LP+ + L L N L P Sbjct: 203 LWLDHN--QLQRLPPELGLLTKLTYLDVSENRLEELPNEISGLVSLTDLDLAQNLLEALP 260 Query: 559 MDIVE 573 I + Sbjct: 261 DGIAK 265 Score = 69.3 bits (168), Expect = 7e-12 Identities = 51/171 (29%), Positives = 78/171 (45%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 I L ++ V D SN + LP+ L L VL ++ L +LPA LE L Sbjct: 102 IKHLQSLQVADFSSNPIPKLPSGFSQLKNLTVLGLNDMSLTTLPADFGSLTQLESLELRE 161 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXX 363 N L LP+T+ +L L+RL + N++ LP ++ L L N ++ Sbjct: 162 NLLKHLPETIS-QLTKLKRLDLGDNEIEDLPPYLGYLPGLHELWLDHNQLQRLPPELGLL 220 Query: 364 XXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKL 516 S+N L ELP + L SL +LD++ N + LPD + L++L Sbjct: 221 TKLTYLDVSEN--RLEELPNEISGLVSLTDLDLAQNLLEALPDGIAKLSRL 269
>LRC40_CHICK (Q5ZLN0) Leucine-rich repeat-containing protein 40| Length = 603 Score = 76.6 bits (187), Expect = 5e-14 Identities = 51/161 (31%), Positives = 83/161 (51%) Frame = +1 Query: 22 VVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRL 201 + VLDV NQL SLP+++G L L+ L+VS N L+S+P + + L+ L N+L+ L Sbjct: 107 LTVLDVHDNQLTSLPSALGQLENLQKLDVSHNKLKSIPEELLQLSHLKGLLLQHNELSHL 166 Query: 202 PDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXX 381 PD G +L SL L +++N LT +P S + + L L+ N ++ Sbjct: 167 PDGFG-QLVSLEELDLSNNHLTDIPKSFALLINLVRLNLACNQLKDLPADISAMKSLRQL 225 Query: 382 XXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGC 504 ++N +L +P L + SL +L + N + LP+ C Sbjct: 226 DCTKN--YLESVPSELASMASLEQLYLRKNKLRSLPELPSC 264 Score = 74.3 bits (181), Expect = 2e-13 Identities = 56/190 (29%), Positives = 93/190 (48%), Gaps = 1/190 (0%) Frame = +1 Query: 7 ARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFN 186 A L+N+V L++ NQLK LP I + LR L+ + N L+S+P+ + +LE+L N Sbjct: 194 ALLINLVRLNLACNQLKDLPADISAMKSLRQLDCTKNYLESVPSELASMASLEQLYLRKN 253 Query: 187 QLTRLPDTLGFELHSLRRLSVNSNKLTSL-PFSTSHMTALRALDARLNCIRAXXXXXXXX 363 +L LP+ +L L+ L N++ L + H+ +L L+ R N I++ Sbjct: 254 KLRSLPELPSCKL--LKELHAGENQIEILNAENLKHLNSLSVLELRDNKIKS-------- 303 Query: 364 XXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNP 543 +P + LL L LD++ N IS LP ++G L++L + GNP Sbjct: 304 -----------------VPDEITLLQKLERLDLANNDISRLPYTLGNLSQLKFLALEGNP 346 Query: 544 LICPPMDIVE 573 L D+++ Sbjct: 347 LRTIRRDLLQ 356 Score = 67.8 bits (164), Expect = 2e-11 Identities = 48/172 (27%), Positives = 82/172 (47%) Frame = +1 Query: 31 LDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDT 210 L + SNQL+ L + L L VL+V N L SLP+ + + L++L+ + N+L +P+ Sbjct: 87 LILASNQLRCLSEDVRLLPALTVLDVHDNQLTSLPSALGQLENLQKLDVSHNKLKSIPEE 146 Query: 211 LGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXS 390 L +L L+ L + N+L+ LP + +L LD N + + Sbjct: 147 L-LQLSHLKGLLLQHNELSHLPDGFGQLVSLEELDLSNNHLTDIPKSFALLINLVRLNLA 205 Query: 391 QNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPL 546 N L++LP + + SLR+LD + N + +P + +A L + N L Sbjct: 206 CN--QLKDLPADISAMKSLRQLDCTKNYLESVPSELASMASLEQLYLRKNKL 255 Score = 61.2 bits (147), Expect = 2e-09 Identities = 50/159 (31%), Positives = 72/159 (45%) Frame = +1 Query: 91 LRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDTLGFELHSLRRLSVNSNKLTS 270 L L ++ N L+ L + AL L+ + NQLT LP LG +L +L++L V+ NKL S Sbjct: 84 LTKLILASNQLRCLSEDVRLLPALTVLDVHDNQLTSLPSALG-QLENLQKLDVSHNKLKS 142 Query: 271 LPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLR 450 +P ++ L+ L + N L LP G G L SL Sbjct: 143 IPEELLQLSHLKGLLLQHN-------------------------ELSHLPDGFGQLVSLE 177 Query: 451 ELDISYNSISVLPDSMGCLAKLNKFSAVGNPLICPPMDI 567 ELD+S N ++ +P S L L + + N L P DI Sbjct: 178 ELDLSNNHLTDIPKSFALLINLVRLNLACNQLKDLPADI 216 Score = 48.5 bits (114), Expect = 1e-05 Identities = 28/94 (29%), Positives = 49/94 (52%) Frame = +1 Query: 31 LDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDT 210 LD+R+N L SLP + L++L+V+N+S N + P+ + ALE + + NQ+ + Sbjct: 478 LDIRNNVLTSLPEEMEALTRLQVINLSFNRFKVFPSVLYRMLALETILLSNNQVGSIDPL 537 Query: 211 LGFELHSLRRLSVNSNKLTSLPFSTSHMTALRAL 312 ++ L L + +N L +P + LR L Sbjct: 538 QLKKMEQLGTLDLQNNDLLQVPPELGNCETLRTL 571 Score = 43.1 bits (100), Expect = 6e-04 Identities = 27/95 (28%), Positives = 50/95 (52%), Gaps = 1/95 (1%) Frame = +1 Query: 46 NQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDTLGFEL 225 N++ S+ + L KL L++ N+L SLP +E L+ +N +FN+ P L + + Sbjct: 460 NKISSVSLELCTLHKLTHLDIRNNVLTSLPEEMEALTRLQVINLSFNRFKVFPSVL-YRM 518 Query: 226 HSLRRLSVNSNKLTSL-PFSTSHMTALRALDARLN 327 +L + +++N++ S+ P M L LD + N Sbjct: 519 LALETILLSNNQVGSIDPLQLKKMEQLGTLDLQNN 553 Score = 36.6 bits (83), Expect = 0.052 Identities = 40/184 (21%), Positives = 66/184 (35%), Gaps = 26/184 (14%) Frame = +1 Query: 82 LSKLRVLNVSGNLLQSLPATIEEC---RALEELNANFNQLTRLPDTL------------G 216 ++ L++L+ S + +P + + +N + NQLT +P + G Sbjct: 399 ITTLKLLDYSEKQVAVIPDDVFSAVRSNPVTSVNFSKNQLTAIPPRIVELKDSVCDVNFG 458 Query: 217 FE-----------LHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXX 363 F LH L L + +N LTSLP +T L+ ++ N + Sbjct: 459 FNKISSVSLELCTLHKLTHLDIRNNVLTSLPEEMEALTRLQVINLSFNRFKVFPSVLYRM 518 Query: 364 XXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNP 543 S N + P L + L LD+ N + +P +G L GNP Sbjct: 519 LALETILLSNNQVGSID-PLQLKKMEQLGTLDLQNNDLLQVPPELGNCETLRTLLLEGNP 577 Query: 544 LICP 555 P Sbjct: 578 FRTP 581
>RSU1_HUMAN (Q15404) Ras suppressor protein 1 (Rsu-1) (RSP-1)| Length = 276 Score = 75.1 bits (183), Expect = 1e-13 Identities = 63/192 (32%), Positives = 86/192 (44%), Gaps = 5/192 (2%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 IA L N+ VL+ +NQ++ LP I L KL+ LN+ N L +LP ALE L+ + Sbjct: 58 IAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNRLNTLPRGFGSLPALEVLDLTY 117 Query: 184 NQLTR--LPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXX 357 N L+ LP F L +LR L ++ N LP +T L+ L R N Sbjct: 118 NNLSENSLPGNF-FYLTTLRALYLSDNDFEILPPDIGKLTKLQILSLRDN---------- 166 Query: 358 XXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCL---AKLNKFS 528 L LP +G LT L+EL I N ++VLP +G L + F Sbjct: 167 ---------------DLISLPKEIGELTQLKELHIQGNRLTVLPPELGNLDLTGQKQVFK 211 Query: 529 AVGNPLICPPMD 564 A NP + P D Sbjct: 212 AENNPWVTPIAD 223 Score = 43.1 bits (100), Expect = 6e-04 Identities = 46/178 (25%), Positives = 71/178 (39%), Gaps = 28/178 (15%) Frame = +1 Query: 124 QSLPATIEECRALE--ELNANFNQLTRLPDTLG-FELHSLRRLSVNSNKLTSLPFSTSHM 294 +SL +EE R E++ + ++ + D G F L + +L ++ NKLT +P + + + Sbjct: 2 KSLKKLVEESREKNQPEVDMSDRGISNMLDVNGLFTLSHITQLVLSHNKLTMVPPNIAEL 61 Query: 295 TALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNS 474 L L+ N I N L LP G G L +L LD++YN+ Sbjct: 62 KNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNR--LNTLPRGFGSLPALEVLDLTYNN 119 Query: 475 IS-------------------------VLPDSMGCLAKLNKFSAVGNPLICPPMDIVE 573 +S +LP +G L KL S N LI P +I E Sbjct: 120 LSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQILSLRDNDLISLPKEIGE 177
>RSU1_MOUSE (Q01730) Ras suppressor protein 1 (Rsu-1) (RSP-1)| Length = 276 Score = 74.7 bits (182), Expect = 2e-13 Identities = 62/192 (32%), Positives = 84/192 (43%), Gaps = 5/192 (2%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 +A L N+ VL+ +NQ++ LP I L KL+ LN+ N L +LP R LE L + Sbjct: 58 VAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNRLNTLPRGFGSSRLLEVLELTY 117 Query: 184 NQLTR--LPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXX 357 N L LP F L +LR L ++ N LP +T L+ L R N Sbjct: 118 NNLNEHSLPGNF-FYLTTLRALYLSDNDFEILPPDIGKLTKLQILSLRDN---------- 166 Query: 358 XXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCL---AKLNKFS 528 L LP +G LT L+EL I N ++VLP +G L + F Sbjct: 167 ---------------DLISLPKEIGELTQLKELHIQGNRLTVLPPELGNLDLTGQKQVFK 211 Query: 529 AVGNPLICPPMD 564 A NP + P D Sbjct: 212 AENNPWVTPIAD 223 Score = 50.8 bits (120), Expect = 3e-06 Identities = 34/92 (36%), Positives = 48/92 (52%) Frame = +1 Query: 1 GIARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNAN 180 G +RLL V+ L + SLP + L+ LR L +S N + LP I + L+ L+ Sbjct: 105 GSSRLLEVLELTYNNLNEHSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQILSLR 164 Query: 181 FNQLTRLPDTLGFELHSLRRLSVNSNKLTSLP 276 N L LP +G EL L+ L + N+LT LP Sbjct: 165 DNDLISLPKEIG-ELTQLKELHIQGNRLTVLP 195 Score = 37.7 bits (86), Expect = 0.023 Identities = 43/178 (24%), Positives = 70/178 (39%), Gaps = 28/178 (15%) Frame = +1 Query: 124 QSLPATIEECRALE--ELNANFNQLTRLPDTLG-FELHSLRRLSVNSNKLTSLPFSTSHM 294 +SL +EE R E++ + ++ + D G F L + +L ++ NKLT++P + + + Sbjct: 2 KSLKKLVEESREKNQPEVDMSDRGISSMLDVNGLFSLAHITQLVLSHNKLTTVPPNVAEL 61 Query: 295 TALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNS 474 L L+ N I N L LP G G L L+++YN+ Sbjct: 62 KNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNR--LNTLPRGFGSSRLLEVLELTYNN 119 Query: 475 IS-------------------------VLPDSMGCLAKLNKFSAVGNPLICPPMDIVE 573 ++ +LP +G L KL S N LI P +I E Sbjct: 120 LNEHSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQILSLRDNDLISLPKEIGE 177
>LRC40_MOUSE (Q9CRC8) Leucine-rich repeat-containing protein 40| Length = 602 Score = 73.9 bits (180), Expect = 3e-13 Identities = 49/162 (30%), Positives = 78/162 (48%) Frame = +1 Query: 31 LDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDT 210 L + SN+L+SL + + L L VL++ N L SLP+ I E L++LN + N+L LP+ Sbjct: 87 LIISSNKLQSLSDDLRLLPALTVLDIHDNQLTSLPSAIRELDNLQKLNVSHNKLKILPEE 146 Query: 211 LGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXS 390 + L +LR L + N+LT +P H++ L LD N + S Sbjct: 147 I-TSLKNLRTLHLQHNELTCIPEGFEHLSCLEDLDLSSNRLATVPADFALLSSLLRLNLS 205 Query: 391 QNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKL 516 N L+ LP + + L+ LD N + +P +G + L Sbjct: 206 SN--QLKNLPAEISRMKRLKHLDCDANLLETVPPDVGSMESL 245 Score = 71.6 bits (174), Expect = 1e-12 Identities = 52/162 (32%), Positives = 81/162 (50%), Gaps = 1/162 (0%) Frame = +1 Query: 22 VVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRL 201 + VLD+ NQL SLP++I L L+ LNVS N L+ LP I + L L+ N+LT + Sbjct: 107 LTVLDIHDNQLTSLPSAIRELDNLQKLNVSHNKLKILPEEITSLKNLRTLHLQHNELTCI 166 Query: 202 PDTLGFE-LHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXX 378 P+ GFE L L L ++SN+L ++P + +++L L+ N ++ Sbjct: 167 PE--GFEHLSCLEDLDLSSNRLATVPADFALLSSLLRLNLSSNQLKNLPAEISRMKRLKH 224 Query: 379 XXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGC 504 N L +P +G + SL L + N + VLP+ C Sbjct: 225 LDCDAN--LLETVPPDVGSMESLELLYLRRNKLRVLPEFPSC 264 Score = 67.4 bits (163), Expect = 3e-11 Identities = 57/181 (31%), Positives = 85/181 (46%), Gaps = 1/181 (0%) Frame = +1 Query: 7 ARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFN 186 A L +++ L++ SNQLK+LP I + +L+ L+ NLL+++P + +LE L N Sbjct: 194 ALLSSLLRLNLSSNQLKNLPAEISRMKRLKHLDCDANLLETVPPDVGSMESLELLYLRRN 253 Query: 187 QLTRLPDTLGFELHSLRRLSVNSNKLTSLPFS-TSHMTALRALDARLNCIRAXXXXXXXX 363 +L LP+ L+ L + N++ L H+ A+ LD R N Sbjct: 254 KLRVLPEFP--SCRQLKELHLAENQIEKLGAEHLQHLQAILVLDLRGN------------ 299 Query: 364 XXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNP 543 LR +P + LL SL LD+S N IS LP S+G L L + GNP Sbjct: 300 -------------KLRSVPEEMALLQSLERLDLSNNDISSLPCSLGNL-HLKFLALEGNP 345 Query: 544 L 546 L Sbjct: 346 L 346 Score = 58.5 bits (140), Expect = 1e-08 Identities = 49/159 (30%), Positives = 72/159 (45%) Frame = +1 Query: 91 LRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDTLGFELHSLRRLSVNSNKLTS 270 L L +S N LQSL + AL L+ + NQLT LP + EL +L++L+V+ NKL Sbjct: 84 LTKLIISSNKLQSLSDDLRLLPALTVLDIHDNQLTSLPSAIR-ELDNLQKLNVSHNKLKI 142 Query: 271 LPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLR 450 LP + + LR L + N + S N L +P LL+SL Sbjct: 143 LPEEITSLKNLRTLHLQHNELTCIPEGFEHLSCLEDLDLSSN--RLATVPADFALLSSLL 200 Query: 451 ELDISYNSISVLPDSMGCLAKLNKFSAVGNPLICPPMDI 567 L++S N + LP + + +L N L P D+ Sbjct: 201 RLNLSSNQLKNLPAEISRMKRLKHLDCDANLLETVPPDV 239 Score = 49.3 bits (116), Expect = 8e-06 Identities = 45/188 (23%), Positives = 80/188 (42%), Gaps = 4/188 (2%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVL---NVSGNLLQSLPATIEECRALE-EL 171 I + + +LD Q +P+ + +K ++ N S N L +P I E + + ++ Sbjct: 395 IHAIATLKLLDYSDKQATLIPDDLFDATKTTLITSINFSKNQLCEIPQRIVELKEMVLDI 454 Query: 172 NANFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXX 351 N +FN+L+ + L L L L + +N L+SLP S +T L+ ++ N + Sbjct: 455 NLSFNKLSFISHELCL-LQKLTFLDLRNNFLSSLPEEMSSLTKLQTINLSFNRFKVFPEV 513 Query: 352 XXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSA 531 S N + P + L+ +L LD+ N + +P +G +L Sbjct: 514 LYRISTLEAVLISNNQVGSVD-PQKMKLMENLNTLDLQNNDLLQIPPELGNCVQLRTLLL 572 Query: 532 VGNPLICP 555 GNP P Sbjct: 573 DGNPFRVP 580 Score = 38.5 bits (88), Expect = 0.014 Identities = 49/214 (22%), Positives = 83/214 (38%), Gaps = 43/214 (20%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECR----ALE-- 165 + L ++VLD+R N+L+S+P + L L L++S N + SLP ++ ALE Sbjct: 285 LQHLQAILVLDLRGNKLRSVPEEMALLQSLERLDLSNNDISSLPCSLGNLHLKFLALEGN 344 Query: 166 -------ELNANFNQ------------------------LTRLPDTLGFELHS---LRRL 243 E+ A Q LP +H+ L+ L Sbjct: 345 PLRTIRREIIAKGTQEVLKYLRSKIKDDRTNQNDSVPETAMTLPSEARVNIHAIATLKLL 404 Query: 244 SVNSNKLTSLP---FSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHFLRE 414 + + T +P F + T + +++ N + + +F+ L Sbjct: 405 DYSDKQATLIPDDLFDATKTTLITSINFSKNQL-CEIPQRIVELKEMVLDINLSFNKLSF 463 Query: 415 LPYGLGLLTSLRELDISYNSISVLPDSMGCLAKL 516 + + L LL L LD+ N +S LP+ M L KL Sbjct: 464 ISHELCLLQKLTFLDLRNNFLSSLPEEMSSLTKL 497
>LRRC2_HUMAN (Q9BYS8) Leucine-rich repeat-containing protein 2| Length = 371 Score = 71.6 bits (174), Expect = 1e-12 Identities = 54/178 (30%), Positives = 85/178 (47%), Gaps = 4/178 (2%) Frame = +1 Query: 28 VLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFN-QLTRLP 204 +LD+ NQ+ LP IGCL L+ LNV N L+S+P + +C LE L+ + N +L LP Sbjct: 148 ILDLPKNQISHLPAEIGCLKNLKELNVGFNYLKSIPPELGDCENLERLDCSGNLELMELP 207 Query: 205 DTLGFELHSLRRLS---VNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXX 375 FEL +L++++ +++NK +S+P M+ L+ LD N Sbjct: 208 ----FELSNLKQVTFVDISANKFSSVPICVLRMSNLQWLDISSN---------------- 247 Query: 376 XXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPLI 549 L +LP + L L+ + N ++ LP SM L KL G+ L+ Sbjct: 248 ---------NLTDLPQDIDRLEELQSFLLYKNKLTYLPYSMLNLKKLTLLVVSGDHLV 296 Score = 50.8 bits (120), Expect = 3e-06 Identities = 48/180 (26%), Positives = 74/180 (41%) Frame = +1 Query: 28 VLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPD 207 V ++ LP+S+ + LR +S L+Q +P I+ +A+ L+ NQ++ LP Sbjct: 102 VFELSGEHWTELPDSLKEQTHLREWYISNTLIQIIPTYIQLFQAMRILDLPKNQISHLPA 161 Query: 208 TLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXX 387 +G L +L+ L+V N L S+P L LD N Sbjct: 162 EIGC-LKNLKELNVGFNYLKSIPPELGDCENLERLDCSGNLE------------------ 202 Query: 388 SQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPLICPPMDI 567 L ELP+ L L + +DIS N S +P + ++ L N L P DI Sbjct: 203 ------LMELPFELSNLKQVTFVDISANKFSSVPICVLRMSNLQWLDISSNNLTDLPQDI 256 Score = 46.2 bits (108), Expect = 7e-05 Identities = 31/103 (30%), Positives = 54/103 (52%), Gaps = 1/103 (0%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNL-LQSLPATIEECRALEELNAN 180 I L N+ L+V N LKS+P +G L L+ SGNL L LP + + + ++ + Sbjct: 163 IGCLKNLKELNVGFNYLKSIPPELGDCENLERLDCSGNLELMELPFELSNLKQVTFVDIS 222 Query: 181 FNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRA 309 N+ + +P + + +L+ L ++SN LT LP + L++ Sbjct: 223 ANKFSSVPICV-LRMSNLQWLDISSNNLTDLPQDIDRLEELQS 264
>FLII_DROME (Q24020) Protein flightless-1 (Flightless-I)| Length = 1256 Score = 71.6 bits (174), Expect = 1e-12 Identities = 61/188 (32%), Positives = 85/188 (45%), Gaps = 3/188 (1%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 I L N+ LD+ N L LP+ + + L LN+S N L L A +E + LE LN + Sbjct: 215 IDSLANLCELDLSHNSLPKLPDCVYNVVTLVRLNLSDNELTELTAGVELWQRLESLNLSR 274 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLT--SLPFSTSHMTALRALDARLNCIRAXXXXXX 357 NQL LP L +L LRRL VN NKL +P + AL A N Sbjct: 275 NQLVALPAAL-CKLPKLRRLLVNDNKLNFEGIPSGIGKLGALEVFSAANN---------- 323 Query: 358 XXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVG 537 L +P GL +L++L++S N + LPD++ L L++ Sbjct: 324 ---------------LLEMVPEGLCRCGALKQLNLSCNRLITLPDAIHLLEGLDQLDLRN 368 Query: 538 NP-LICPP 558 NP L+ PP Sbjct: 369 NPELVMPP 376 Score = 68.6 bits (166), Expect = 1e-11 Identities = 52/175 (29%), Positives = 82/175 (46%), Gaps = 3/175 (1%) Frame = +1 Query: 31 LDVRSNQLKS--LPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLP 204 LD+R NQLK+ +P + L +L L++S N L+ +P +E + L LN + NQ+ +P Sbjct: 80 LDLRHNQLKNSGIPPELFHLEELTTLDLSHNKLKEVPEGLERAKNLIVLNLSNNQIESIP 139 Query: 205 DTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXX-XXXXXXXX 381 L L L L ++ N+L +LP T + L+ LD N + Sbjct: 140 TPLFIHLTDLLFLDLSHNRLETLPPQTRRLINLKTLDLSHNPLELFQLRQLPSLQSLEVL 199 Query: 382 XXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPL 546 S L P + L +L ELD+S+NS+ LPD + + L + + N L Sbjct: 200 KMSGTQRTLLNFPTSIDSLANLCELDLSHNSLPKLPDCVYNVVTLVRLNLSDNEL 254 Score = 54.7 bits (130), Expect = 2e-07 Identities = 55/190 (28%), Positives = 86/190 (45%), Gaps = 8/190 (4%) Frame = +1 Query: 1 GIARLLNVVVLDVRSNQLKSLPNSIGC-LSKLRVLNVSGNLLQSLPATIEECRALEELNA 177 G+ R N++VL++ +NQ++S+P + L+ L L++S N L++LP L+ L+ Sbjct: 118 GLERAKNLIVLNLSNNQIESIPTPLFIHLTDLLFLDLSHNRLETLPPQTRRLINLKTLDL 177 Query: 178 NFN-----QLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTS--HMTALRALDARLNCIR 336 + N QL +LP L SL L ++ + T L F TS + L LD N + Sbjct: 178 SHNPLELFQLRQLP-----SLQSLEVLKMSGTQRTLLNFPTSIDSLANLCELDLSHNSLP 232 Query: 337 AXXXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKL 516 S N L EL G+ L L L++S N + LP ++ L KL Sbjct: 233 KLPDCVYNVVTLVRLNLSDN--ELTELTAGVELWQRLESLNLSRNQLVALPAALCKLPKL 290 Query: 517 NKFSAVGNPL 546 + N L Sbjct: 291 RRLLVNDNKL 300 Score = 50.1 bits (118), Expect = 5e-06 Identities = 31/104 (29%), Positives = 56/104 (53%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 + +L ++V D + N + +P+ IG L L V + + NLL+ +P + C AL++LN + Sbjct: 287 LPKLRRLLVNDNKLN-FEGIPSGIGKLGALEVFSAANNLLEMVPEGLCRCGALKQLNLSC 345 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALD 315 N+L LPD + L L +L + +N +P S + +L+ Sbjct: 346 NRLITLPDAIHL-LEGLDQLDLRNNPELVMPPKPSEASKATSLE 388
>CYAA_PODAN (Q01513) Adenylate cyclase (EC 4.6.1.1) (ATP pyrophosphate-lyase)| (Adenylyl cyclase) Length = 2145 Score = 71.6 bits (174), Expect = 1e-12 Identities = 40/108 (37%), Positives = 66/108 (61%), Gaps = 1/108 (0%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQL 192 L ++ L++ +N+LK LP + LR LN+S NLL + P + + L +L+ +FN + Sbjct: 848 LTGLLKLNLANNKLKQLPREFEAFAVLRTLNISSNLLNNFPPFLAKLENLVDLDLSFNTI 907 Query: 193 TRLPDTLGFELHSLRRLSVNSNKLT-SLPFSTSHMTALRALDARLNCI 333 LPD +G ++ SL RL + +N+L+ SLP S ++ +LR LD + N I Sbjct: 908 QSLPDNVG-QMTSLERLVITNNELSGSLPPSFKNLRSLRELDIKYNAI 954 Score = 65.1 bits (157), Expect = 1e-10 Identities = 49/206 (23%), Positives = 97/206 (47%), Gaps = 18/206 (8%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQ-SLPATIEECRALEELNAN 180 +A+L N+V LD+ N ++SLP+++G ++ L L ++ N L SLP + + R+L EL+ Sbjct: 891 LAKLENLVDLDLSFNTIQSLPDNVGQMTSLERLVITNNELSGSLPPSFKNLRSLRELDIK 950 Query: 181 FNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRA---------LDARLNCI 333 +N ++ + D + +L L LS N ++ + + +++ + A + + Sbjct: 951 YNAISNI-DVIS-QLPKLEILSATRNNISQFSGTFERVRSIKLNWNPITKFEIKAPVPTL 1008 Query: 334 RAXXXXXXXXXXXXXXXXSQNF--------HFLRELPYGLGLLTSLRELDISYNSISVLP 489 +A + + ++ LP +G L L I++NS+ LP Sbjct: 1009 KALNLSNAQLASIDESFHNMSNLERLELDKNYFVSLPAHIGNLRRLEYFSIAHNSVGELP 1068 Query: 490 DSMGCLAKLNKFSAVGNPLICPPMDI 567 +GCL +L + GN + PM++ Sbjct: 1069 PEIGCLTELKRLDVRGNNIRKLPMEL 1094 Score = 56.6 bits (135), Expect = 5e-08 Identities = 47/175 (26%), Positives = 79/175 (45%), Gaps = 3/175 (1%) Frame = +1 Query: 31 LDVRSNQLKSLPNSI-GCLSKLRVLNVSGNLLQSLPAT-IEECRALEELNANFNQLTRLP 204 +D+ L ++P + +++ LN+S NL +P I C L ++ N N+ LP Sbjct: 759 IDLSGRSLSAIPVQLYPRANEIISLNLSRNLSLQVPRDFISVCPNLRDIKFNNNEARALP 818 Query: 205 DTLGFELHSLRRLSVNSNKLTSLPFSTSH-MTALRALDARLNCIRAXXXXXXXXXXXXXX 381 + G+ L L ++N+L SL + H +T L L+ N ++ Sbjct: 819 KSFGYASR-LTMLDASNNRLESLESAALHNLTGLLKLNLANNKLKQLPREFEAFAVLRTL 877 Query: 382 XXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPL 546 S N L P L L +L +LD+S+N+I LPD++G + L + N L Sbjct: 878 NISSNL--LNNFPPFLAKLENLVDLDLSFNTIQSLPDNVGQMTSLERLVITNNEL 930 Score = 44.7 bits (104), Expect = 2e-04 Identities = 31/86 (36%), Positives = 42/86 (48%), Gaps = 1/86 (1%) Frame = +1 Query: 82 LSKLRVLNVSGNLLQSLPA-TIEECRALEELNANFNQLTRLPDTLGFELHSLRRLSVNSN 258 L LRVLN+S N L +P +I+ L EL + N+L LP E L+ L +N N Sbjct: 1257 LENLRVLNLSYNDLSDMPQRSIKSWPQLVELYLSGNELASLPADDLEEYSMLQTLHINGN 1316 Query: 259 KLTSLPFSTSHMTALRALDARLNCIR 336 K T+LP S L D N ++ Sbjct: 1317 KFTNLPADISRAKKLTVFDCGSNSLK 1342 Score = 43.9 bits (102), Expect = 3e-04 Identities = 23/67 (34%), Positives = 35/67 (52%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 I L + + N + LP IGCL++L+ L+V GN ++ LP + L+ LNA+ Sbjct: 1048 IGNLRRLEYFSIAHNSVGELPPEIGCLTELKRLDVRGNNIRKLPMELWWANKLDYLNASS 1107 Query: 184 NQLTRLP 204 N L P Sbjct: 1108 NVLENFP 1114
>FLII_CAEEL (P34268) Protein flightless-1 homolog| Length = 1257 Score = 69.7 bits (169), Expect = 6e-12 Identities = 53/213 (24%), Positives = 92/213 (43%), Gaps = 26/213 (12%) Frame = +1 Query: 7 ARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGN----------------------- 117 A L++++ LD+ +N+L LP I LS L+ L +S N Sbjct: 147 ANLIDLLFLDLSNNKLDMLPPQIRRLSMLQSLKLSNNPLNHFQLKQLPSMTSLSVLHMSN 206 Query: 118 ---LLQSLPATIEECRALEELNANFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTS 288 L ++P T+++ L +++ + N L +P+ L F+L +LR+L+++ NK+ L + Sbjct: 207 TNRTLDNIPPTLDDMHNLRDVDFSENNLPIVPEAL-FKLRNLRKLNLSGNKIEKLNMTEG 265 Query: 289 HMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISY 468 L L+ N + + N +P G+G L L L +SY Sbjct: 266 EWENLETLNMSHNQLTVLPDCVVKLTRLTKLYAANNQLTFEGIPSGIGKLIQLTVLHLSY 325 Query: 469 NSISVLPDSMGCLAKLNKFSAVGNPLICPPMDI 567 N + ++P+ + KL K N LI P I Sbjct: 326 NKLELVPEGISRCVKLQKLKLDHNRLITLPEGI 358 Score = 59.3 bits (142), Expect = 8e-09 Identities = 50/159 (31%), Positives = 71/159 (44%), Gaps = 2/159 (1%) Frame = +1 Query: 19 NVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTR 198 N+ +D N L +P ++ L LR LN+SGN ++ L T E LE LN + NQLT Sbjct: 223 NLRDVDFSENNLPIVPEALFKLRNLRKLNLSGNKIEKLNMTEGEWENLETLNMSHNQLTV 282 Query: 199 LPDTLGFELHSLRRLSVNSNKLT--SLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXX 372 LPD + +L L +L +N+LT +P + L L N + Sbjct: 283 LPDCV-VKLTRLTKLYAANNQLTFEGIPSGIGKLIQLTVLHLSYNKLELVPEGISRCVKL 341 Query: 373 XXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLP 489 N L LP G+ LL L+ LD+ N V+P Sbjct: 342 QKLKLDHN--RLITLPEGIHLLPDLKVLDLHENENLVMP 378 Score = 48.9 bits (115), Expect = 1e-05 Identities = 44/185 (23%), Positives = 87/185 (47%), Gaps = 4/185 (2%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEE---LN 174 I R+ ++ ++D+ NQL+ +P ++ VLN+S N ++++P ++ C L + L+ Sbjct: 99 IFRMKDLTIIDLSRNQLREVPTNLEYAKGSIVLNLSYNNIETIPNSV--CANLIDLLFLD 156 Query: 175 ANFNQLTRLPDTLGFELHSLRRLS-VNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXX 351 + N+L LP +RRLS + S KL++ P + + L ++ Sbjct: 157 LSNNKLDMLPP-------QIRRLSMLQSLKLSNNPLNHFQLKQLPSM------------- 196 Query: 352 XXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSA 531 S L +P L + +LR++D S N++ ++P+++ L L K + Sbjct: 197 ----TSLSVLHMSNTNRTLDNIPPTLDDMHNLRDVDFSENNLPIVPEALFKLRNLRKLNL 252 Query: 532 VGNPL 546 GN + Sbjct: 253 SGNKI 257
>FLII_MOUSE (Q9JJ28) Protein flightless-1 homolog| Length = 1271 Score = 69.3 bits (168), Expect = 7e-12 Identities = 55/208 (26%), Positives = 93/208 (44%), Gaps = 26/208 (12%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLL----------------------- 123 L +++ LD+ N+L+SLP + L L+ L ++GN L Sbjct: 150 LTDLLYLDLSENRLESLPPQMRRLVHLQTLVLNGNPLLHAQLRQLPAMMALQTLHLRNTQ 209 Query: 124 ---QSLPATIEECRALEELNANFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHM 294 +LP ++E L +++ + N LTR+P+ L + L SLRRL+++SN++ L Sbjct: 210 RTQSNLPTSLEGLSNLSDVDLSCNDLTRVPECL-YTLPSLRRLNLSSNQIAELSLCIDQW 268 Query: 295 TALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNS 474 L L+ N + + + N LP G+G LTSL E + N+ Sbjct: 269 VHLETLNLSRNQLTSLPSAICKLTKLKKLYLNSNKLDFDGLPSGIGKLTSLEEFMAANNN 328 Query: 475 ISVLPDSMGCLAKLNKFSAVGNPLICPP 558 + ++P+S+ KL K N L+ P Sbjct: 329 LELIPESLCRCPKLKKLVLNKNRLVTLP 356 Score = 61.2 bits (147), Expect = 2e-09 Identities = 50/161 (31%), Positives = 75/161 (46%), Gaps = 2/161 (1%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQL 192 L N+ +D+ N L +P + L LR LN+S N + L I++ LE LN + NQL Sbjct: 222 LSNLSDVDLSCNDLTRVPECLYTLPSLRRLNLSSNQIAELSLCIDQWVHLETLNLSRNQL 281 Query: 193 TRLPDTLGFELHSLRRLSVNSNKLT--SLPFSTSHMTALRALDARLNCIRAXXXXXXXXX 366 T LP + +L L++L +NSNKL LP +T+L A N + Sbjct: 282 TSLPSAI-CKLTKLKKLYLNSNKLDFDGLPSGIGKLTSLEEFMAANNNLELIPESLCRCP 340 Query: 367 XXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLP 489 ++N L LP + LT ++ LD+ N V+P Sbjct: 341 KLKKLVLNKNR--LVTLPEAIHFLTEIQVLDVRENPSLVMP 379 Score = 58.5 bits (140), Expect = 1e-08 Identities = 38/110 (34%), Positives = 65/110 (59%), Gaps = 2/110 (1%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQ--SLPATIEECRALEELNA 177 I + +++ L++ NQL SLP++I L+KL+ L ++ N L LP+ I + +LEE A Sbjct: 265 IDQWVHLETLNLSRNQLTSLPSAICKLTKLKKLYLNSNKLDFDGLPSGIGKLTSLEEFMA 324 Query: 178 NFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLN 327 N L +P++L L++L +N N+L +LP + +T ++ LD R N Sbjct: 325 ANNNLELIPESL-CRCPKLKKLVLNKNRLVTLPEAIHFLTEIQVLDVREN 373 Score = 56.2 bits (134), Expect = 6e-08 Identities = 45/184 (24%), Positives = 82/184 (44%), Gaps = 3/184 (1%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKS--LPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNA 177 ++ L ++ + R+N LK+ +P+ I L L VL++S N L P +E + + LN Sbjct: 75 LSSLPSLRAIVARANSLKNSGVPDDIFKLDDLSVLDLSHNQLTECPRELENAKNMLVLNL 134 Query: 178 NFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLN-CIRAXXXXX 354 + N + +P+ L L L L ++ N+L SLP + L+ L N + A Sbjct: 135 SHNGIDSIPNQLFINLTDLLYLDLSENRLESLPPQMRRLVHLQTLVLNGNPLLHAQLRQL 194 Query: 355 XXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAV 534 LP L L++L ++D+S N ++ +P+ + L L + + Sbjct: 195 PAMMALQTLHLRNTQRTQSNLPTSLEGLSNLSDVDLSCNDLTRVPECLYTLPSLRRLNLS 254 Query: 535 GNPL 546 N + Sbjct: 255 SNQI 258 Score = 48.1 bits (113), Expect = 2e-05 Identities = 39/143 (27%), Positives = 65/143 (45%), Gaps = 2/143 (1%) Frame = +1 Query: 76 GCLSKLRVLNVSGNLLQS--LPATIEECRALEELNANFNQLTRLPDTLGFELHSLRRLSV 249 G L +R +++SGN + P ++ +L L N L LP+ L L L LSV Sbjct: 5 GVLPFVRGVDLSGNDFKGGYFPENVKAMTSLRWLKLNRTGLCYLPEELA-ALQKLEHLSV 63 Query: 250 NSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHFLRELPYGL 429 + N LT+L S + +LRA+ AR N ++ + + L E P L Sbjct: 64 SHNHLTTLHGELSSLPSLRAIVARANSLKNSGVPDDIFKLDDLSVLDLSHNQLTECPREL 123 Query: 430 GLLTSLRELDISYNSISVLPDSM 498 ++ L++S+N I +P+ + Sbjct: 124 ENAKNMLVLNLSHNGIDSIPNQL 146
>LRC40_PONPY (Q5RFE9) Leucine-rich repeat-containing protein 40| Length = 602 Score = 68.6 bits (166), Expect = 1e-11 Identities = 53/162 (32%), Positives = 82/162 (50%), Gaps = 1/162 (0%) Frame = +1 Query: 22 VVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRL 201 + VLD+ NQL SLP++I L L+ LNVS N L+ LP I R L+ L N+LT + Sbjct: 107 LTVLDIHDNQLTSLPSAIRELQNLQKLNVSHNKLKILPEEITNLRNLKCLYLQHNELTCI 166 Query: 202 PDTLGFELHS-LRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXX 378 + GFE S L L +++N+LT++P S S +++L L+ N +++ Sbjct: 167 SE--GFEQFSNLEDLDLSNNRLTTVPASFSSLSSLVRLNLSSNELKSLPAEINRMKRLKH 224 Query: 379 XXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGC 504 + N L +P L + SL L + N + LP+ C Sbjct: 225 LDCNSN--LLETIPPELAGMESLELLYLRRNKLRFLPEFPSC 264 Score = 67.0 bits (162), Expect = 4e-11 Identities = 57/179 (31%), Positives = 86/179 (48%), Gaps = 1/179 (0%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQL 192 L ++V L++ SN+LKSLP I + +L+ L+ + NLL+++P + +LE L N+L Sbjct: 196 LSSLVRLNLSSNELKSLPAEINRMKRLKHLDCNSNLLETIPPELAGMESLELLYLRRNKL 255 Query: 193 TRLPDTLGFELHSLRRLSVNSNKLTSLPFS-TSHMTALRALDARLNCIRAXXXXXXXXXX 369 LP+ L L+ L V N++ L H+ ++ LD R N Sbjct: 256 RFLPEFPSCSL--LKELHVGENQIEMLEAEHLKHLNSILVLDLRDN-------------- 299 Query: 370 XXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPL 546 L+ +P + LL SL LD+S N IS LP S+G L L + GNPL Sbjct: 300 -----------KLKSVPDEIILLQSLERLDLSNNDISSLPYSLGNL-HLKFLALEGNPL 346 Score = 62.8 bits (151), Expect = 7e-10 Identities = 44/162 (27%), Positives = 76/162 (46%) Frame = +1 Query: 31 LDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDT 210 L + +N+L+SL + + L L VL++ N L SLP+ I E + L++LN + N+L LP+ Sbjct: 87 LIISNNKLQSLTDDLRLLPALTVLDIHDNQLTSLPSAIRELQNLQKLNVSHNKLKILPEE 146 Query: 211 LGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXS 390 + L +L+ L + N+LT + + L LD N + S Sbjct: 147 I-TNLRNLKCLYLQHNELTCISEGFEQFSNLEDLDLSNNRLTTVPASFSSLSSLVRLNLS 205 Query: 391 QNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKL 516 N L+ LP + + L+ LD + N + +P + + L Sbjct: 206 SN--ELKSLPAEINRMKRLKHLDCNSNLLETIPPELAGMESL 245 Score = 54.7 bits (130), Expect = 2e-07 Identities = 46/159 (28%), Positives = 72/159 (45%) Frame = +1 Query: 91 LRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDTLGFELHSLRRLSVNSNKLTS 270 L L +S N LQSL + AL L+ + NQLT LP + EL +L++L+V+ NKL Sbjct: 84 LTKLIISNNKLQSLTDDLRLLPALTVLDIHDNQLTSLPSAIR-ELQNLQKLNVSHNKLKI 142 Query: 271 LPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLR 450 LP +++ L+ L + N + S N L +P L+SL Sbjct: 143 LPEEITNLRNLKCLYLQHNELTCISEGFEQFSNLEDLDLSNN--RLTTVPASFSSLSSLV 200 Query: 451 ELDISYNSISVLPDSMGCLAKLNKFSAVGNPLICPPMDI 567 L++S N + LP + + +L N L P ++ Sbjct: 201 RLNLSSNELKSLPAEINRMKRLKHLDCNSNLLETIPPEL 239 Score = 45.8 bits (107), Expect = 9e-05 Identities = 28/95 (29%), Positives = 50/95 (52%), Gaps = 1/95 (1%) Frame = +1 Query: 46 NQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDTLGFEL 225 N+L + + L KL L++ N L SLP +E L+ +N +FN+ LP+ L + + Sbjct: 459 NKLSFISLELCVLQKLTFLDLRNNFLNSLPEEVESLVRLQTINLSFNRFKMLPEVL-YRI 517 Query: 226 HSLRRLSVNSNKLTSL-PFSTSHMTALRALDARLN 327 +L + +++N++ S+ P M L LD + N Sbjct: 518 FTLETILISNNQVGSVDPQKMKMMENLTTLDLQNN 552 Score = 45.1 bits (105), Expect = 1e-04 Identities = 28/100 (28%), Positives = 48/100 (48%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQL 192 L + LD+R+N L SLP + L +L+ +N+S N + LP + LE + + NQ+ Sbjct: 471 LQKLTFLDLRNNFLNSLPEEVESLVRLQTINLSFNRFKMLPEVLYRIFTLETILISNNQV 530 Query: 193 TRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRAL 312 + + +L L + +N L +P + LR L Sbjct: 531 GSVDPQKMKMMENLTTLDLQNNDLLQIPPELGNCVNLRTL 570 Score = 43.5 bits (101), Expect = 4e-04 Identities = 41/188 (21%), Positives = 76/188 (40%), Gaps = 4/188 (2%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVL---NVSGNLLQSLPATIEECRAL-EEL 171 I ++ + +LD Q +P+ + K ++ N S N L +P + E + + ++ Sbjct: 395 IRAIITLKILDYSDKQATLIPDEVFDAVKSNIITSINFSKNQLCEIPKRMVELKEMVSDV 454 Query: 172 NANFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXX 351 N +FN+L+ + L L L L + +N L SLP + L+ ++ N + Sbjct: 455 NLSFNKLSFISLELCV-LQKLTFLDLRNNFLNSLPEEVESLVRLQTINLSFNRFKMLPEV 513 Query: 352 XXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSA 531 S N + P + ++ +L LD+ N + +P +G L Sbjct: 514 LYRIFTLETILISNNQVGSVD-PQKMKMMENLTTLDLQNNDLLQIPPELGNCVNLRTLLL 572 Query: 532 VGNPLICP 555 GNP P Sbjct: 573 DGNPFRVP 580 Score = 39.3 bits (90), Expect = 0.008 Identities = 19/47 (40%), Positives = 32/47 (68%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATI 144 + L +++VLD+R N+LKS+P+ I L L L++S N + SLP ++ Sbjct: 285 LKHLNSILVLDLRDNKLKSVPDEIILLQSLERLDLSNNDISSLPYSL 331
>LRC40_HUMAN (Q9H9A6) Leucine-rich repeat-containing protein 40| Length = 602 Score = 68.6 bits (166), Expect = 1e-11 Identities = 53/162 (32%), Positives = 82/162 (50%), Gaps = 1/162 (0%) Frame = +1 Query: 22 VVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRL 201 + VLD+ NQL SLP++I L L+ LNVS N L+ LP I R L+ L N+LT + Sbjct: 107 LTVLDIHDNQLTSLPSAIRELENLQKLNVSHNKLKILPEEITNLRNLKCLYLQHNELTCI 166 Query: 202 PDTLGFE-LHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXX 378 + GFE L +L L +++N LT++P S S +++L L+ N +++ Sbjct: 167 SE--GFEQLSNLEDLDLSNNHLTTVPASFSSLSSLVRLNLSSNELKSLPAEINRMKRLKH 224 Query: 379 XXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGC 504 + N L +P L + SL L + N + LP+ C Sbjct: 225 LDCNSN--LLETIPPELAGMESLELLYLRRNKLRFLPEFPSC 264 Score = 67.0 bits (162), Expect = 4e-11 Identities = 57/179 (31%), Positives = 86/179 (48%), Gaps = 1/179 (0%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQL 192 L ++V L++ SN+LKSLP I + +L+ L+ + NLL+++P + +LE L N+L Sbjct: 196 LSSLVRLNLSSNELKSLPAEINRMKRLKHLDCNSNLLETIPPELAGMESLELLYLRRNKL 255 Query: 193 TRLPDTLGFELHSLRRLSVNSNKLTSLPFS-TSHMTALRALDARLNCIRAXXXXXXXXXX 369 LP+ L L+ L V N++ L H+ ++ LD R N Sbjct: 256 RFLPEFPSCSL--LKELHVGENQIEMLEAEHLKHLNSILVLDLRDN-------------- 299 Query: 370 XXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPL 546 L+ +P + LL SL LD+S N IS LP S+G L L + GNPL Sbjct: 300 -----------KLKSVPDEIILLRSLERLDLSNNDISSLPYSLGNL-HLKFLALEGNPL 346 Score = 63.2 bits (152), Expect = 5e-10 Identities = 44/162 (27%), Positives = 76/162 (46%) Frame = +1 Query: 31 LDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDT 210 L + +N+L+SL + + L L VL++ N L SLP+ I E L++LN + N+L LP+ Sbjct: 87 LIISNNKLQSLTDDLRLLPALTVLDIHDNQLTSLPSAIRELENLQKLNVSHNKLKILPEE 146 Query: 211 LGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXS 390 + L +L+ L + N+LT + ++ L LD N + S Sbjct: 147 I-TNLRNLKCLYLQHNELTCISEGFEQLSNLEDLDLSNNHLTTVPASFSSLSSLVRLNLS 205 Query: 391 QNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKL 516 N L+ LP + + L+ LD + N + +P + + L Sbjct: 206 SN--ELKSLPAEINRMKRLKHLDCNSNLLETIPPELAGMESL 245 Score = 55.5 bits (132), Expect = 1e-07 Identities = 46/159 (28%), Positives = 72/159 (45%) Frame = +1 Query: 91 LRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDTLGFELHSLRRLSVNSNKLTS 270 L L +S N LQSL + AL L+ + NQLT LP + EL +L++L+V+ NKL Sbjct: 84 LTKLIISNNKLQSLTDDLRLLPALTVLDIHDNQLTSLPSAIR-ELENLQKLNVSHNKLKI 142 Query: 271 LPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLR 450 LP +++ L+ L + N + S N L +P L+SL Sbjct: 143 LPEEITNLRNLKCLYLQHNELTCISEGFEQLSNLEDLDLSNN--HLTTVPASFSSLSSLV 200 Query: 451 ELDISYNSISVLPDSMGCLAKLNKFSAVGNPLICPPMDI 567 L++S N + LP + + +L N L P ++ Sbjct: 201 RLNLSSNELKSLPAEINRMKRLKHLDCNSNLLETIPPEL 239 Score = 47.0 bits (110), Expect = 4e-05 Identities = 29/100 (29%), Positives = 53/100 (53%), Gaps = 1/100 (1%) Frame = +1 Query: 31 LDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDT 210 +D+ N+L + + L KL L++ N L SLP +E L+ +N +FN+ LP+ Sbjct: 454 VDLSFNKLSFISLELCVLQKLTFLDLRNNFLNSLPEEMESLVRLQTINLSFNRFKMLPEV 513 Query: 211 LGFELHSLRRLSVNSNKLTSL-PFSTSHMTALRALDARLN 327 L + + +L + +++N++ S+ P M L LD + N Sbjct: 514 L-YRIFTLETILISNNQVGSVDPQKMKMMENLTTLDLQNN 552 Score = 44.3 bits (103), Expect = 2e-04 Identities = 28/100 (28%), Positives = 48/100 (48%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQL 192 L + LD+R+N L SLP + L +L+ +N+S N + LP + LE + + NQ+ Sbjct: 471 LQKLTFLDLRNNFLNSLPEEMESLVRLQTINLSFNRFKMLPEVLYRIFTLETILISNNQV 530 Query: 193 TRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRAL 312 + + +L L + +N L +P + LR L Sbjct: 531 GSVDPQKMKMMENLTTLDLQNNDLLQIPPELGNCVNLRTL 570 Score = 38.9 bits (89), Expect = 0.010 Identities = 19/47 (40%), Positives = 32/47 (68%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATI 144 + L +++VLD+R N+LKS+P+ I L L L++S N + SLP ++ Sbjct: 285 LKHLNSILVLDLRDNKLKSVPDEIILLRSLERLDLSNNDISSLPYSL 331
>LRC40_MACFA (Q4R3P6) Leucine-rich repeat-containing protein 40| Length = 602 Score = 68.2 bits (165), Expect = 2e-11 Identities = 58/179 (32%), Positives = 86/179 (48%), Gaps = 1/179 (0%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQL 192 L ++V L++ SNQLKSLP I + +L+ L+ + NLL+++P + +LE L N+L Sbjct: 196 LSSLVRLNLSSNQLKSLPAEINRMKRLKHLDCNSNLLETIPPELAGMESLELLYLRRNKL 255 Query: 193 TRLPDTLGFELHSLRRLSVNSNKLTSLPFS-TSHMTALRALDARLNCIRAXXXXXXXXXX 369 LP+ L L+ L V N++ L H+ ++ LD R N Sbjct: 256 RFLPEFPSCSL--LKELHVGENQIEMLEAEHLKHLNSILVLDLRDN-------------- 299 Query: 370 XXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPL 546 L+ +P + LL SL LD+S N IS LP S+G L L + GNPL Sbjct: 300 -----------KLKSVPDEIILLQSLERLDLSNNDISSLPYSLGNL-HLKFLALEGNPL 346 Score = 67.4 bits (163), Expect = 3e-11 Identities = 51/162 (31%), Positives = 82/162 (50%), Gaps = 1/162 (0%) Frame = +1 Query: 22 VVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRL 201 + VLD+ NQL SLP+++ L L+ LNVS N L+ P I R L+ L N+LT + Sbjct: 107 LTVLDIHDNQLTSLPSAMRELENLQKLNVSHNKLKIFPEEITNLRNLKCLYLQHNELTCI 166 Query: 202 PDTLGFE-LHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXX 378 + GFE L +L L +++N+LT++P S S +++L L+ N +++ Sbjct: 167 SE--GFEQLSNLEDLDLSNNRLTTVPASFSSLSSLVRLNLSSNQLKSLPAEINRMKRLKH 224 Query: 379 XXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGC 504 + N L +P L + SL L + N + LP+ C Sbjct: 225 LDCNSN--LLETIPPELAGMESLELLYLRRNKLRFLPEFPSC 264 Score = 53.1 bits (126), Expect = 5e-07 Identities = 45/159 (28%), Positives = 71/159 (44%) Frame = +1 Query: 91 LRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDTLGFELHSLRRLSVNSNKLTS 270 L L +S N LQSL + AL L+ + NQLT LP + EL +L++L+V+ NKL Sbjct: 84 LTKLIISNNKLQSLTDDLRLLPALTVLDIHDNQLTSLPSAMR-ELENLQKLNVSHNKLKI 142 Query: 271 LPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLR 450 P +++ L+ L + N + S N L +P L+SL Sbjct: 143 FPEEITNLRNLKCLYLQHNELTCISEGFEQLSNLEDLDLSNN--RLTTVPASFSSLSSLV 200 Query: 451 ELDISYNSISVLPDSMGCLAKLNKFSAVGNPLICPPMDI 567 L++S N + LP + + +L N L P ++ Sbjct: 201 RLNLSSNQLKSLPAEINRMKRLKHLDCNSNLLETIPPEL 239 Score = 45.1 bits (105), Expect = 1e-04 Identities = 28/95 (29%), Positives = 50/95 (52%), Gaps = 1/95 (1%) Frame = +1 Query: 46 NQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDTLGFEL 225 N+L + + L KL L++ N L SLP +E L+ +N +FN+ LP+ L + + Sbjct: 459 NKLSFISLELCMLQKLTFLDLRNNFLNSLPEEMESLVRLQTINLSFNRFKMLPEVL-YRI 517 Query: 226 HSLRRLSVNSNKLTSL-PFSTSHMTALRALDARLN 327 +L + +++N++ S+ P M L LD + N Sbjct: 518 FTLETILISNNQVGSVDPQKMKMMENLTTLDLQNN 552 Score = 44.7 bits (104), Expect = 2e-04 Identities = 28/103 (27%), Positives = 49/103 (47%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 + L + LD+R+N L SLP + L +L+ +N+S N + LP + LE + + Sbjct: 468 LCMLQKLTFLDLRNNFLNSLPEEMESLVRLQTINLSFNRFKMLPEVLYRIFTLETILISN 527 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRAL 312 NQ+ + + +L L + +N L +P + LR L Sbjct: 528 NQVGSVDPQKMKMMENLTTLDLQNNDLLQIPPELGNCVNLRTL 570 Score = 43.1 bits (100), Expect = 6e-04 Identities = 41/188 (21%), Positives = 76/188 (40%), Gaps = 4/188 (2%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVL---NVSGNLLQSLPATIEECRAL-EEL 171 I ++ + +LD Q +P+ + K ++ N S N L +P + E + + ++ Sbjct: 395 IHAIITLKILDYSDKQATLIPDEVFNAVKSNIITSINFSKNQLCEIPKRMVELKEMVSDV 454 Query: 172 NANFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXX 351 N +FN+L+ + L L L L + +N L SLP + L+ ++ N + Sbjct: 455 NLSFNKLSFISLELCM-LQKLTFLDLRNNFLNSLPEEMESLVRLQTINLSFNRFKMLPEV 513 Query: 352 XXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSA 531 S N + P + ++ +L LD+ N + +P +G L Sbjct: 514 LYRIFTLETILISNNQVGSVD-PQKMKMMENLTTLDLQNNDLLQIPPELGNCVNLRTLLL 572 Query: 532 VGNPLICP 555 GNP P Sbjct: 573 DGNPFRVP 580
>FLII_HUMAN (Q13045) Protein flightless-1 homolog| Length = 1269 Score = 68.2 bits (165), Expect = 2e-11 Identities = 54/208 (25%), Positives = 94/208 (45%), Gaps = 26/208 (12%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLL----------------------- 123 L +++ LD+ N+L+SLP + L L+ L ++GN L Sbjct: 150 LTDLLYLDLSENRLESLPPQMRRLVHLQTLVLNGNPLLHAQLRQLPAMTALQTLHLRSTQ 209 Query: 124 ---QSLPATIEECRALEELNANFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHM 294 +LP ++E L +++ + N LTR+P+ L + L SLRRL+++SN++T L Sbjct: 210 RTQSNLPTSLEGLSNLADVDLSCNDLTRVPECL-YTLPSLRRLNLSSNQITELSLCIDQW 268 Query: 295 TALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNS 474 + L+ N + + + N LP G+G LT+L E + N+ Sbjct: 269 VHVETLNLSRNQLTSLPSAICKLSKLKKLYLNSNKLDFDGLPSGIGKLTNLEEFMAANNN 328 Query: 475 ISVLPDSMGCLAKLNKFSAVGNPLICPP 558 + ++P+S+ KL K N L+ P Sbjct: 329 LELVPESLCRCPKLRKLVLNKNHLVTLP 356 Score = 60.1 bits (144), Expect = 4e-09 Identities = 49/161 (30%), Positives = 73/161 (45%), Gaps = 2/161 (1%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQL 192 L N+ +D+ N L +P + L LR LN+S N + L I++ +E LN + NQL Sbjct: 222 LSNLADVDLSCNDLTRVPECLYTLPSLRRLNLSSNQITELSLCIDQWVHVETLNLSRNQL 281 Query: 193 TRLPDTLGFELHSLRRLSVNSNKLT--SLPFSTSHMTALRALDARLNCIRAXXXXXXXXX 366 T LP + +L L++L +NSNKL LP +T L A N + Sbjct: 282 TSLPSAI-CKLSKLKKLYLNSNKLDFDGLPSGIGKLTNLEEFMAANNNLELVPESLCRCP 340 Query: 367 XXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLP 489 ++N L LP + LT + LD+ N V+P Sbjct: 341 KLRKLVLNKNH--LVTLPEAIHFLTEIEVLDVRENPNLVMP 379 Score = 58.9 bits (141), Expect = 1e-08 Identities = 41/110 (37%), Positives = 62/110 (56%), Gaps = 2/110 (1%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLL--QSLPATIEECRALEELNA 177 I + ++V L++ NQL SLP++I LSKL+ L ++ N L LP+ I + LEE A Sbjct: 265 IDQWVHVETLNLSRNQLTSLPSAICKLSKLKKLYLNSNKLDFDGLPSGIGKLTNLEEFMA 324 Query: 178 NFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLN 327 N L +P++L LR+L +N N L +LP + +T + LD R N Sbjct: 325 ANNNLELVPESL-CRCPKLRKLVLNKNHLVTLPEAIHFLTEIEVLDVREN 373 Score = 57.4 bits (137), Expect = 3e-08 Identities = 45/184 (24%), Positives = 82/184 (44%), Gaps = 3/184 (1%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKS--LPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNA 177 ++ L ++ + R+N LK+ +P+ I L L VL++S N L P +E + + LN Sbjct: 75 LSSLPSLRAIVARANSLKNSGVPDDIFKLDDLSVLDLSHNQLTECPRELENAKNMLVLNL 134 Query: 178 NFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLN-CIRAXXXXX 354 + N + +P+ L L L L ++ N+L SLP + L+ L N + A Sbjct: 135 SHNSIDTIPNQLFINLTDLLYLDLSENRLESLPPQMRRLVHLQTLVLNGNPLLHAQLRQL 194 Query: 355 XXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAV 534 LP L L++L ++D+S N ++ +P+ + L L + + Sbjct: 195 PAMTALQTLHLRSTQRTQSNLPTSLEGLSNLADVDLSCNDLTRVPECLYTLPSLRRLNLS 254 Query: 535 GNPL 546 N + Sbjct: 255 SNQI 258 Score = 50.8 bits (120), Expect = 3e-06 Identities = 40/143 (27%), Positives = 66/143 (46%), Gaps = 2/143 (1%) Frame = +1 Query: 76 GCLSKLRVLNVSGNLLQS--LPATIEECRALEELNANFNQLTRLPDTLGFELHSLRRLSV 249 G L +R +++SGN + P ++ +L L N L LP+ L L L LSV Sbjct: 5 GVLPFVRGVDLSGNDFKGGYFPENVKAMTSLRWLKLNRTGLCYLPEELA-ALQKLEHLSV 63 Query: 250 NSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHFLRELPYGL 429 + N LT+L S + +LRA+ AR N ++ + + L E P L Sbjct: 64 SHNNLTTLHGELSSLPSLRAIVARANSLKNSGVPDDIFKLDDLSVLDLSHNQLTECPREL 123 Query: 430 GLLTSLRELDISYNSISVLPDSM 498 ++ L++S+NSI +P+ + Sbjct: 124 ENAKNMLVLNLSHNSIDTIPNQL 146 Score = 32.0 bits (71), Expect = 1.3 Identities = 21/68 (30%), Positives = 33/68 (48%) Frame = +1 Query: 1 GIARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNAN 180 GI +L N+ +N L+ +P S+ KLR L ++ N L +LP I +E L+ Sbjct: 312 GIGKLTNLEEFMAANNNLELVPESLCRCPKLRKLVLNKNHLVTLPEAIHFLTEIEVLDVR 371 Query: 181 FNQLTRLP 204 N +P Sbjct: 372 ENPNLVMP 379
>RPK1_IPONI (P93194) Receptor-like protein kinase precursor (EC 2.7.11.1)| Length = 1109 Score = 68.2 bits (165), Expect = 2e-11 Identities = 55/163 (33%), Positives = 78/163 (47%), Gaps = 4/163 (2%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLK-SLPNSIGCLSKLRVLNVSGNLLQS-LPATIEECRALEELNA 177 + L NV + + SNQL S+P +G L KL LN+S N+L+ LP+ + C L EL+A Sbjct: 519 LGNLKNVTAIYLSSNQLSGSIPPELGSLVKLEHLNLSHNILKGILPSELSNCHKLSELDA 578 Query: 178 NFNQLT-RLPDTLGFELHSLRRLSVNSNKLTS-LPFSTSHMTALRALDARLNCIRAXXXX 351 + N L +P TLG L L +LS+ N + +P S L L N + Sbjct: 579 SHNLLNGSIPSTLG-SLTELTKLSLGENSFSGGIPTSLFQSNKLLNLQLGGNLLAGDIPP 637 Query: 352 XXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSIS 480 S N +LP LG L L ELD+S+N++S Sbjct: 638 VGALQALRSLNLSSN-KLNGQLPIDLGKLKMLEELDVSHNNLS 679 Score = 49.3 bits (116), Expect = 8e-06 Identities = 48/163 (29%), Positives = 72/163 (44%), Gaps = 4/163 (2%) Frame = +1 Query: 64 PNSIGCLSKLRVLNVSGNLLQ-SLPATIEECRALEELNANFNQLTR-LPDTLGFELHSLR 237 P S+ + L + +GN L S+P+ I L L + NQ + +P +LG + +L+ Sbjct: 157 PESLLSIPHLETVYFTGNGLNGSIPSNIGNMSELTTLWLDDNQFSGPVPSSLG-NITTLQ 215 Query: 238 RLSVNSNKLT-SLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHFLRE 414 L +N N L +LP + +++ L LD R N + N F Sbjct: 216 ELYLNDNNLVGTLPVTLNNLENLVYLDVRNNSLVGAIPLDFVSCKQIDTISLSNNQFTGG 275 Query: 415 LPYGLGLLTSLRELDISYNSIS-VLPDSMGCLAKLNKFSAVGN 540 LP GLG TSLRE ++S +P G L KL+ GN Sbjct: 276 LPPGLGNCTSLREFGAFSCALSGPIPSCFGQLTKLDTLYLAGN 318 Score = 44.7 bits (104), Expect = 2e-04 Identities = 37/140 (26%), Positives = 64/140 (45%), Gaps = 3/140 (2%) Frame = +1 Query: 61 LPNSIGCLSKLRVLNVSGNLLQS-LPATIEECRALEELNANFNQLT-RLPDTLGFELHSL 234 +P+ G L+KL L ++GN +P + +C+++ +L NQL +P LG L L Sbjct: 300 IPSCFGQLTKLDTLYLAGNHFSGRIPPELGKCKSMIDLQLQQNQLEGEIPGELGM-LSQL 358 Query: 235 RRLSVNSNKLTS-LPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHFLR 411 + L + +N L+ +P S + +L++L N + HF Sbjct: 359 QYLHLYTNNLSGEVPLSIWKIQSLQSLQLYQNNLSGELPVDMTELKQLVSLALYENHFTG 418 Query: 412 ELPYGLGLLTSLRELDISYN 471 +P LG +SL LD++ N Sbjct: 419 VIPQDLGANSSLEVLDLTRN 438 Score = 35.0 bits (79), Expect = 0.15 Identities = 46/182 (25%), Positives = 76/182 (41%), Gaps = 5/182 (2%) Frame = +1 Query: 43 SNQLKSLPNSIGCLSKLRVLNVSGN-LLQSLPATIEECRALEELNANFNQLTR-LPDTLG 216 +N + +LP ++ L L L+V N L+ ++P C+ ++ ++ + NQ T LP LG Sbjct: 222 NNLVGTLPVTLNNLENLVYLDVRNNSLVGAIPLDFVSCKQIDTISLSNNQFTGGLPPGLG 281 Query: 217 FELHSLRRLSVNSNKLTS-LPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQ 393 SLR S L+ +P +T L L N Q Sbjct: 282 -NCTSLREFGAFSCALSGPIPSCFGQLTKLDTLYLAGNHFSGRIPPELGKCKSMIDLQLQ 340 Query: 394 NFHFLRELPYGLGLLTSLRELDISYNSIS-VLPDSMGCLAKLNKFSAVGNPLICP-PMDI 567 E+P LG+L+ L+ L + N++S +P S+ + L N L P+D+ Sbjct: 341 QNQLEGEIPGELGMLSQLQYLHLYTNNLSGEVPLSIWKIQSLQSLQLYQNNLSGELPVDM 400 Query: 568 VE 573 E Sbjct: 401 TE 402
>CYAA_NEUCR (Q01631) Adenylate cyclase (EC 4.6.1.1) (ATP pyrophosphate-lyase)| (Adenylyl cyclase) Length = 2300 Score = 67.8 bits (164), Expect = 2e-11 Identities = 37/111 (33%), Positives = 65/111 (58%), Gaps = 1/111 (0%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 +++L ++ L++ +N L+SLP ++G LR LN+S N L P+ I E + +L+ +F Sbjct: 959 LSKLTGLLKLNLANNCLRSLPPTLGAYKSLRTLNISSNFLDVFPSFICELETIVDLDLSF 1018 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTS-LPFSTSHMTALRALDARLNCI 333 N + LPD L +L +L + + +N+L+ + S + +LR LD R N I Sbjct: 1019 NSINNLPDNL-MKLRNLEKFVITNNRLSGPISESVRDLVSLRELDIRYNQI 1068 Score = 62.8 bits (151), Expect = 7e-10 Identities = 50/154 (32%), Positives = 73/154 (47%), Gaps = 2/154 (1%) Frame = +1 Query: 100 LNVSGNLLQSLPAT-IEECRALEELNANFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLP 276 LN+S NL +P I+ C AL ++ N N+ LP + L L V++N+L L Sbjct: 897 LNLSRNLSLDVPRDFIQACTALRDIKYNNNEAQALPKSFA-TASKLTYLDVSNNRLQDLD 955 Query: 277 FST-SHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRE 453 S S +T L L+ NC+R+ S NF L P + L ++ + Sbjct: 956 HSELSKLTGLLKLNLANNCLRSLPPTLGAYKSLRTLNISSNF--LDVFPSFICELETIVD 1013 Query: 454 LDISYNSISVLPDSMGCLAKLNKFSAVGNPLICP 555 LD+S+NSI+ LPD++ L L KF N L P Sbjct: 1014 LDLSFNSINNLPDNLMKLRNLEKFVITNNRLSGP 1047 Score = 61.6 bits (148), Expect = 2e-09 Identities = 55/169 (32%), Positives = 76/169 (44%), Gaps = 1/169 (0%) Frame = +1 Query: 43 SNQLKSLPNSIGCLSKLRVLNVSGNLLQSLP-ATIEECRALEELNANFNQLTRLPDTLGF 219 +N+ ++LP S SKL L+VS N LQ L + + + L +LN N L LP TLG Sbjct: 925 NNEAQALPKSFATASKLTYLDVSNNRLQDLDHSELSKLTGLLKLNLANNCLRSLPPTLG- 983 Query: 220 ELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNF 399 SLR L+++SN L P + + LD N I + N Sbjct: 984 AYKSLRTLNISSNFLDVFPSFICELETIVDLDLSFNSINNLPDNLMKLRNLEKFVITNN- 1042 Query: 400 HFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPL 546 + + L SLRELDI YN IS + D + L +L SA N + Sbjct: 1043 RLSGPISESVRDLVSLRELDIRYNQISTI-DVLSDLPRLEILSADHNQI 1090 Score = 52.0 bits (123), Expect = 1e-06 Identities = 29/67 (43%), Positives = 38/67 (56%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 I L + L + +N L LP IGCL++LR L+V GN ++ LP I LE LNA+ Sbjct: 1162 IGNLKKLDHLSMANNHLGELPPEIGCLTELRTLDVHGNNMRKLPNEIWWANKLEHLNASS 1221 Query: 184 NQLTRLP 204 N LT P Sbjct: 1222 NILTEFP 1228 Score = 49.7 bits (117), Expect = 6e-06 Identities = 33/91 (36%), Positives = 49/91 (53%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 I L+N+ L + SN SLPN IG L KL L+++ N L LP I L L+ + Sbjct: 1139 IDNLMNLERLILDSNYFVSLPNQIGNLKKLDHLSMANNHLGELPPEIGCLTELRTLDVHG 1198 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTSLP 276 N + +LP+ + + + L L+ +SN LT P Sbjct: 1199 NNMRKLPNEIWW-ANKLEHLNASSNILTEFP 1228 Score = 47.4 bits (111), Expect = 3e-05 Identities = 34/87 (39%), Positives = 45/87 (51%), Gaps = 2/87 (2%) Frame = +1 Query: 82 LSKLRVLNVSGNLLQSLP-ATIEECRALEELNANFNQLTRLPDTLGFELHSL-RRLSVNS 255 L +LRVLN+S N L +P TI L EL + N+LT LP E H L + L +N Sbjct: 1373 LPELRVLNLSCNDLSDMPQGTIRSWPQLVELYLSGNELTSLPAEDFLEEHCLLQTLHING 1432 Query: 256 NKLTSLPFSTSHMTALRALDARLNCIR 336 NK +LP S L+ LD N ++ Sbjct: 1433 NKFINLPAEISRAKKLQVLDCSSNNLK 1459 Score = 46.2 bits (108), Expect = 7e-05 Identities = 48/197 (24%), Positives = 81/197 (41%), Gaps = 19/197 (9%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEE-------- 168 L+++ LD+R NQ+ ++ + + L +L +L+ N + + E R+L+ Sbjct: 1055 LVSLRELDIRYNQISTI-DVLSDLPRLEILSADHNQISKFSGSFERLRSLKLNSNPIVKF 1113 Query: 169 -----------LNANFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALD 315 LN + QL + +++ L +L RL ++SN SLP ++ L L Sbjct: 1114 EVKAPVPTLKILNLSNAQLASIDESID-NLMNLERLILDSNYFVSLPNQIGNLKKLDHLS 1172 Query: 316 ARLNCIRAXXXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDS 495 N L ELP +G LT LR LD+ N++ LP+ Sbjct: 1173 MANN-------------------------HLGELPPEIGCLTELRTLDVHGNNMRKLPNE 1207 Query: 496 MGCLAKLNKFSAVGNPL 546 + KL +A N L Sbjct: 1208 IWWANKLEHLNASSNIL 1224 Score = 33.1 bits (74), Expect = 0.58 Identities = 28/89 (31%), Positives = 46/89 (51%), Gaps = 9/89 (10%) Frame = +1 Query: 22 VVVLDVRSNQLKSLPNSI----GCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQ 189 +V L + N+L SLP CL L+ L+++GN +LPA I + L+ L+ + N Sbjct: 1400 LVELYLSGNELTSLPAEDFLEEHCL--LQTLHINGNKFINLPAEISRAKKLQVLDCSSNN 1457 Query: 190 L----TRLPDTLGFELH-SLRRLSVNSNK 261 L T +P + + LR L+++ NK Sbjct: 1458 LKYNVTNVPYDWNWNFNRDLRYLNLSGNK 1486
>PHLPP_CAEEL (Q09564) Protein phosphatase PHLPP-like protein (EC 3.1.3.16)| Length = 1036 Score = 66.2 bits (160), Expect = 6e-11 Identities = 35/96 (36%), Positives = 59/96 (61%) Frame = +1 Query: 10 RLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQ 189 R+ ++ V+D+ +NQ+ S P + LS LR LN+S N + S+P+ R L+ LN + NQ Sbjct: 195 RVHSLQVIDLSANQILSFPIQLTLLSHLRQLNLSSNYISSVPSECSNMRRLQYLNLSNNQ 254 Query: 190 LTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMT 297 L LPD++ EL +L+ L ++ N+ + +P H+T Sbjct: 255 LDTLPDSIS-ELQNLQSLDISFNQFSQIPPCLFHLT 289 Score = 51.2 bits (121), Expect = 2e-06 Identities = 51/212 (24%), Positives = 85/212 (40%), Gaps = 36/212 (16%) Frame = +1 Query: 31 LDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDT 210 L++ SN + S+P+ + +L+ LN+S N L +LP +I E + L+ L+ +FNQ +++P Sbjct: 225 LNLSSNYISSVPSECSNMRRLQYLNLSNNQLDTLPDSISELQNLQSLDISFNQFSQIPPC 284 Query: 211 LGFELHSLRRLSVNS------------------------------NKLTSLP------FS 282 L + RL+ N+ +T L S Sbjct: 285 LFHLTLEMWRLAGNNIEKIDRVGEMQIQKIDLRRNVLDTSFRLDIENITHLDLRDNSMIS 344 Query: 283 TSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDI 462 T H+T LR L ++C R + H L + + L +L+ L + Sbjct: 345 TVHLTNLRFLKV-IHCERLQLSSLHLSGESLTHVYAD--HNLLDSLVVMPLPQNLQTLSL 401 Query: 463 SYNSISVLPDSMGCLAKLNKFSAVGNPLICPP 558 S+N LPD + L A N L+ P Sbjct: 402 SFNHFRNLPDWISDCPNLTFLRANNNSLVALP 433 Score = 44.3 bits (103), Expect = 2e-04 Identities = 40/154 (25%), Positives = 69/154 (44%), Gaps = 1/154 (0%) Frame = +1 Query: 31 LDVRSNQLKSLPNSI-GCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPD 207 +D QL +P I +++++LN+ N L S P T + L + D Sbjct: 143 VDASDEQLTLIPEQILNNEARVQILNLRRNSLISRPPTEKSMAPLGYI-----------D 191 Query: 208 TLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXX 387 L + +HSL+ + +++N++ S P + ++ LR L+ N I + Sbjct: 192 DL-YRVHSLQVIDLSANQILSFPIQLTLLSHLRQLNLSSNYISSVPSECSNMRRLQYLNL 250 Query: 388 SQNFHFLRELPYGLGLLTSLRELDISYNSISVLP 489 S N L LP + L +L+ LDIS+N S +P Sbjct: 251 SNNQ--LDTLPDSISELQNLQSLDISFNQFSQIP 282 Score = 43.1 bits (100), Expect = 6e-04 Identities = 40/160 (25%), Positives = 67/160 (41%), Gaps = 1/160 (0%) Frame = +1 Query: 19 NVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTR 198 N+ L + N ++LP+ I L L + N L +LP I ++L + A N++ Sbjct: 395 NLQTLSLSFNHFRNLPDWISDCPNLTFLRANNNSLVALPERIFYSQSLRSIFAFINEIEH 454 Query: 199 LPDTLGFELHSLRRLSVNSNKLTSLP-FSTSHMTALRALDARLNCIRAXXXXXXXXXXXX 375 +PD E + L L + NKL+SLP S + LR L+ N I Sbjct: 455 IPDF--GEENCLETLILYKNKLSSLPKHFFSILPRLRQLNISSNFIELLPYFDGSSFCRL 512 Query: 376 XXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDS 495 N + + + L+ +D+S+N ++ DS Sbjct: 513 QILRCANNYLTENSVPVIVNMKHLKIIDLSHNRLNSFDDS 552 Score = 37.7 bits (86), Expect = 0.023 Identities = 29/86 (33%), Positives = 46/86 (53%), Gaps = 2/86 (2%) Frame = +1 Query: 82 LSKLRVLNVSGNLLQSLP-ATIEECRALEELNANFNQLTRLPDTLGFELHSLRRLSVNSN 258 + L+++++S N L S + + LE+LN + N+LTRL D L L L+ L +SN Sbjct: 533 MKHLKIIDLSHNRLNSFDDSALSSLELLEDLNLSSNRLTRLADCLAL-LPCLQVLRAHSN 591 Query: 259 KLTSLP-FSTSHMTALRALDARLNCI 333 +L +P F S+ L +D N I Sbjct: 592 QLVHVPEFRASNQ--LHTIDVSSNNI 615 Score = 35.0 bits (79), Expect = 0.15 Identities = 34/155 (21%), Positives = 65/155 (41%), Gaps = 2/155 (1%) Frame = +1 Query: 115 NLLQSLPATIEECRALEELNANFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHM 294 N+L++ ++ ++A+ QLT +P+ + ++ L++ N L S P + M Sbjct: 125 NILEAWLTRAQQVEKSNHVDASDEQLTLIPEQILNNEARVQILNLRRNSLISRPPTEKSM 184 Query: 295 TALRALD--ARLNCIRAXXXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISY 468 L +D R++ ++ + + P L LL+ LR+L++S Sbjct: 185 APLGYIDDLYRVHSLQVIDLSA---------------NQILSFPIQLTLLSHLRQLNLSS 229 Query: 469 NSISVLPDSMGCLAKLNKFSAVGNPLICPPMDIVE 573 N IS +P + +L + N L P I E Sbjct: 230 NYISSVPSECSNMRRLQYLNLSNNQLDTLPDSISE 264
>CYAA_USTMA (P49606) Adenylate cyclase (EC 4.6.1.1) (ATP pyrophosphate-lyase)| (Adenylyl cyclase) Length = 2493 Score = 66.2 bits (160), Expect = 6e-11 Identities = 63/214 (29%), Positives = 94/214 (43%), Gaps = 33/214 (15%) Frame = +1 Query: 22 VVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRL 201 +V L + NQL LP+++G L +L +L+ S NLL +LP +I + +AL+EL + N L L Sbjct: 1364 LVKLTLDGNQLVVLPDTLGDLKRLEMLSCSNNLLATLPESIGDLKALKELLVHNNNLKTL 1423 Query: 202 PDTLGFELHSLRRLSVNSNKLTSLPFSTSHMT-------ALRALDARLNCIRAXXXXXXX 360 P TL + SL ++++SN L S P T A A + + R Sbjct: 1424 PQTL-WLCESLAHINLSSNLLESFPAVPDIRTDASVGDAAAAAGTSAVIAARKGSTSSSL 1482 Query: 361 XXXXXXXXXSQNFHF--------------LRELPYG-----------LGLLTSLRELDIS 465 + N + L++L G L LTSL L++S Sbjct: 1483 THRSNTGGANGNINLSTPSEVFVAPLSLSLQKLRLGDNRLGDDVFSVLSELTSLEVLNLS 1542 Query: 466 YNSISVLPD-SMGCLAKLNKFSAVGNPLICPPMD 564 +N I +PD S+ L KL + GN L P D Sbjct: 1543 FNEIFEIPDFSLQTLTKLRELYISGNQLSTIPSD 1576 Score = 64.3 bits (155), Expect = 2e-10 Identities = 36/102 (35%), Positives = 58/102 (56%) Frame = +1 Query: 31 LDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDT 210 L V++N+L LP+ +S LR LN+S N + P I + +L +L+ +FN +T LP Sbjct: 1185 LKVQNNRLFDLPSYFSSISTLRNLNISNNRFEEFPKVICDVPSLVDLDVSFNSITELPAE 1244 Query: 211 LGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIR 336 + L +L R + N+L LP S S + +LR +D R N ++ Sbjct: 1245 IA-NLINLERFILAGNELEKLPDSMSELVSLRTIDLRRNKVQ 1285 Score = 57.8 bits (138), Expect = 2e-08 Identities = 47/176 (26%), Positives = 75/176 (42%), Gaps = 1/176 (0%) Frame = +1 Query: 22 VVVLDVRSNQLKSLP-NSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTR 198 +V LD+ N + LP + + S LR L +S L+ +P ++ L L+ + N++ Sbjct: 1111 IVSLDLSGNPMSDLPLDFVQLCSSLRTLRLSNLALKRIPQSVRHSETLTHLDVSNNRIVE 1170 Query: 199 LPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXX 378 L + L L V +N+L LP S ++ LR L+ N Sbjct: 1171 LAHVSLDLIPELMSLKVQNNRLFDLPSYFSSISTLRNLNISNNRFE-------------- 1216 Query: 379 XXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPL 546 E P + + SL +LD+S+NSI+ LP + L L +F GN L Sbjct: 1217 -----------EFPKVICDVPSLVDLDVSFNSITELPAEIANLINLERFILAGNEL 1261 Score = 48.1 bits (113), Expect = 2e-05 Identities = 50/185 (27%), Positives = 79/185 (42%), Gaps = 2/185 (1%) Frame = +1 Query: 19 NVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTR 198 ++V LDV N + LP I L L ++GN L+ LP ++ E +L ++ N++ Sbjct: 1227 SLVDLDVSFNSITELPAEIANLINLERFILAGNELEKLPDSMSELVSLRTIDLRRNKVQD 1286 Query: 199 LPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCI-RAXXXXXXXXXXXX 375 + LG L L+ + SN + S F + L ++ N + + Sbjct: 1287 VSSLLG--LPRLQNIQAESNNIKS--FEATLGPQLTQVELGRNPLSKVRIAALTTCDLTS 1342 Query: 376 XXXXSQNFHFLRELPYGL-GLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPLIC 552 S N L E GL L +L +L + N + VLPD++G L +L S N L Sbjct: 1343 LDLSSTNMTRLEE---GLFPQLPALVKLTLDGNQLVVLPDTLGDLKRLEMLSCSNNLLAT 1399 Query: 553 PPMDI 567 P I Sbjct: 1400 LPESI 1404 Score = 47.4 bits (111), Expect = 3e-05 Identities = 32/89 (35%), Positives = 54/89 (60%), Gaps = 2/89 (2%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPN-SIGCLSKLRVLNVSGNLLQSLPA-TIEECRALEELNA 177 ++ L ++ VL++ N++ +P+ S+ L+KLR L +SGN L ++P+ + + L L+ Sbjct: 1530 LSELTSLEVLNLSFNEIFEIPDFSLQTLTKLRELYISGNQLSTIPSDDLVVLQELRILHL 1589 Query: 178 NFNQLTRLPDTLGFELHSLRRLSVNSNKL 264 N N+LT LP LG +L L L V +N L Sbjct: 1590 NCNKLTTLPTELG-KLKKLANLDVGNNVL 1617 Score = 47.4 bits (111), Expect = 3e-05 Identities = 52/199 (26%), Positives = 88/199 (44%), Gaps = 11/199 (5%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 IA L+N+ + N+L+ LP+S+ L LR +++ N +Q + + + R L+ + A Sbjct: 1245 IANLINLERFILAGNELEKLPDSMSELVSLRTIDLRRNKVQDVSSLLGLPR-LQNIQAES 1303 Query: 184 NQLTRLPDTLGFE----------LHSLRRLSVNSNKLTSLPFSTSHMTAL-RALDARLNC 330 N + TLG + L +R ++ + LTSL S+++MT L L +L Sbjct: 1304 NNIKSFEATLGPQLTQVELGRNPLSKVRIAALTTCDLTSLDLSSTNMTRLEEGLFPQLPA 1363 Query: 331 IRAXXXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLA 510 + + + + L LP LG L L L S N ++ LP+S+G L Sbjct: 1364 L---------------VKLTLDGNQLVVLPDTLGDLKRLEMLSCSNNLLATLPESIGDLK 1408 Query: 511 KLNKFSAVGNPLICPPMDI 567 L + N L P + Sbjct: 1409 ALKELLVHNNNLKTLPQTL 1427 Score = 45.1 bits (105), Expect = 1e-04 Identities = 30/86 (34%), Positives = 45/86 (52%), Gaps = 1/86 (1%) Frame = +1 Query: 82 LSKLRVLNVSGNLLQSLPA-TIEECRALEELNANFNQLTRLPDTLGFELHSLRRLSVNSN 258 L+ L VLN+S N + +P +++ L EL + NQL+ +P L LR L +N N Sbjct: 1533 LTSLEVLNLSFNEIFEIPDFSLQTLTKLRELYISGNQLSTIPSDDLVVLQELRILHLNCN 1592 Query: 259 KLTSLPFSTSHMTALRALDARLNCIR 336 KLT+LP + L LD N ++ Sbjct: 1593 KLTTLPTELGKLKKLANLDVGNNVLK 1618 Score = 43.9 bits (102), Expect = 3e-04 Identities = 29/83 (34%), Positives = 47/83 (56%), Gaps = 1/83 (1%) Frame = +1 Query: 31 LDVRSNQLKSLPNSI-GCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPD 207 LD+ S + L + L L L + GN L LP T+ + + LE L+ + N L LP+ Sbjct: 1343 LDLSSTNMTRLEEGLFPQLPALVKLTLDGNQLVVLPDTLGDLKRLEMLSCSNNLLATLPE 1402 Query: 208 TLGFELHSLRRLSVNSNKLTSLP 276 ++G +L +L+ L V++N L +LP Sbjct: 1403 SIG-DLKALKELLVHNNNLKTLP 1424 Score = 37.7 bits (86), Expect = 0.023 Identities = 31/113 (27%), Positives = 49/113 (43%), Gaps = 1/113 (0%) Frame = +1 Query: 136 ATIEECRALEELNANFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALD 315 + + E +LE LN +FN++ +PD L LR L ++ N+L+++P + + L+ L Sbjct: 1528 SVLSELTSLEVLNLSFNEIFEIPDFSLQTLTKLRELYISGNQLSTIP--SDDLVVLQELR 1585 Query: 316 -ARLNCIRAXXXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYN 471 LNC + L LP LG L L LD+ N Sbjct: 1586 ILHLNCNK-----------------------LTTLPTELGKLKKLANLDVGNN 1615
>LRC39_MOUSE (Q8BGI7) Leucine-rich repeat-containing protein 39| Length = 337 Score = 65.9 bits (159), Expect = 8e-11 Identities = 49/182 (26%), Positives = 85/182 (46%), Gaps = 1/182 (0%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 I R +++VLD+ N + +P IG L++L+ L +S N ++++P + C +LE+L Sbjct: 102 IGRFQHLIVLDLSRNTISEIPRGIGLLTRLQELILSYNKIKTVPKELSNCTSLEKLELAV 161 Query: 184 NQ-LTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXX 360 N+ ++ LP L +L L L ++ N+ T++P + M AL LD N Sbjct: 162 NRDISDLPPELS-KLLKLTHLDLSMNQFTTIPHAVLDMPALEWLDMGSNS---------- 210 Query: 361 XXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGN 540 L++LP L + SL L + N I+ LP+++ + L N Sbjct: 211 ---------------LQQLPDSLDRMRSLHTLWLQRNEITCLPETIKNMKNLGTLVLSNN 255 Query: 541 PL 546 L Sbjct: 256 KL 257
>LRRC2_MOUSE (Q8VDB8) Leucine-rich repeat-containing protein 2| Length = 371 Score = 65.1 bits (157), Expect = 1e-10 Identities = 54/181 (29%), Positives = 84/181 (46%), Gaps = 4/181 (2%) Frame = +1 Query: 28 VLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFN-QLTRLP 204 +LD+ NQ+ LP IG L L+ LNVS N L+S+P + +C LE L+ + N L LP Sbjct: 148 ILDLPKNQITCLPAEIGRLKNLKELNVSFNHLKSIPPELGDCEHLERLDCSGNLDLMDLP 207 Query: 205 DTLGFELHSLRRLS---VNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXX 375 FEL +L++++ +++NK +S+P M L+ LD N Sbjct: 208 ----FELSNLKQVTFVDISANKFSSVPICVLRMCRLQWLDISSN---------------- 247 Query: 376 XXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPLICP 555 L +LP + L L+ + N ++ LP +M L KL G+ L+ Sbjct: 248 ---------NLSDLPQDIDRLEELQGFLLYKNKLTYLPQAMLNLKKLTLLVVSGDHLVEV 298 Query: 556 P 558 P Sbjct: 299 P 299 Score = 54.3 bits (129), Expect = 2e-07 Identities = 49/180 (27%), Positives = 77/180 (42%) Frame = +1 Query: 28 VLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPD 207 V ++ Q K LP+S+ + L+ + L+Q +P IE +A++ L+ NQ+T LP Sbjct: 102 VFELSGTQWKELPDSLKEQTHLKEWYIHSTLIQIIPTYIELFQAMKILDLPKNQITCLPA 161 Query: 208 TLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXX 387 +G L +L+ L+V+ N L S+P L LD N Sbjct: 162 EIG-RLKNLKELNVSFNHLKSIPPELGDCEHLERLDCSGNLD------------------ 202 Query: 388 SQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPLICPPMDI 567 L +LP+ L L + +DIS N S +P + + +L N L P DI Sbjct: 203 ------LMDLPFELSNLKQVTFVDISANKFSSVPICVLRMCRLQWLDISSNNLSDLPQDI 256 Score = 46.2 bits (108), Expect = 7e-05 Identities = 31/102 (30%), Positives = 53/102 (51%), Gaps = 1/102 (0%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNL-LQSLPATIEECRALEELNAN 180 I RL N+ L+V N LKS+P +G L L+ SGNL L LP + + + ++ + Sbjct: 163 IGRLKNLKELNVSFNHLKSIPPELGDCEHLERLDCSGNLDLMDLPFELSNLKQVTFVDIS 222 Query: 181 FNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALR 306 N+ + +P + + L+ L ++SN L+ LP + L+ Sbjct: 223 ANKFSSVPICV-LRMCRLQWLDISSNNLSDLPQDIDRLEELQ 263
>LRC57_BRARE (Q6DHL5) Leucine-rich repeat-containing protein 57| Length = 238 Score = 64.7 bits (156), Expect = 2e-10 Identities = 39/106 (36%), Positives = 58/106 (54%) Frame = +1 Query: 19 NVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTR 198 N+ +D+ +N+++ LP IG L+ +S N L SLP I + + LE L N NQL + Sbjct: 39 NLRTVDLSNNKIEELPAFIGSFQHLKSFTISCNKLTSLPNDIGKLKKLETLILNGNQLKQ 98 Query: 199 LPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIR 336 LP ++G +L SLR LS++ N+ P + L LD N IR Sbjct: 99 LPSSIG-QLKSLRTLSLSGNQFKEFPSGLGTLRQLDVLDLSKNQIR 143 Score = 60.8 bits (146), Expect = 3e-09 Identities = 36/110 (32%), Positives = 62/110 (56%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 I +L + L + NQLK LP+SIG L LR L++SGN + P+ + R L+ L+ + Sbjct: 80 IGKLKKLETLILNGNQLKQLPSSIGQLKSLRTLSLSGNQFKEFPSGLGTLRQLDVLDLSK 139 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCI 333 NQ+ +P + EL ++ +++N N+++S+ S L+ L NC+ Sbjct: 140 NQIRVVPAEVA-ELQAI-EINLNQNQISSVTQEVSRTPRLKVLRLEENCL 187 Score = 59.7 bits (143), Expect = 6e-09 Identities = 46/155 (29%), Positives = 70/155 (45%), Gaps = 1/155 (0%) Frame = +1 Query: 28 VLDVRSNQLKSLPNSIGCLS-KLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLP 204 V + L P + L+ LR +++S N ++ LPA I + L+ + N+LT LP Sbjct: 18 VFQLTGKGLTEFPEDLQKLTANLRTVDLSNNKIEELPAFIGSFQHLKSFTISCNKLTSLP 77 Query: 205 DTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXX 384 + +G +L L L +N N+L LP S + +LR L Sbjct: 78 NDIG-KLKKLETLILNGNQLKQLPSSIGQLKSLRTL------------------------ 112 Query: 385 XSQNFHFLRELPYGLGLLTSLRELDISYNSISVLP 489 S + + +E P GLG L L LD+S N I V+P Sbjct: 113 -SLSGNQFKEFPSGLGTLRQLDVLDLSKNQIRVVP 146 Score = 57.8 bits (138), Expect = 2e-08 Identities = 34/97 (35%), Positives = 56/97 (57%) Frame = +1 Query: 37 VRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDTLG 216 + N+L SLPN IG L KL L ++GN L+ LP++I + ++L L+ + NQ P LG Sbjct: 68 ISCNKLTSLPNDIGKLKKLETLILNGNQLKQLPSSIGQLKSLRTLSLSGNQFKEFPSGLG 127 Query: 217 FELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLN 327 L L L ++ N++ +P + + L+A++ LN Sbjct: 128 -TLRQLDVLDLSKNQIRVVP---AEVAELQAIEINLN 160 Score = 49.7 bits (117), Expect = 6e-06 Identities = 41/163 (25%), Positives = 68/163 (41%), Gaps = 1/163 (0%) Frame = +1 Query: 88 KLRVLNVSGNLLQSLPATIEECRA-LEELNANFNQLTRLPDTLGFELHSLRRLSVNSNKL 264 K V ++G L P +++ A L ++ + N++ LP +G H L+ +++ NKL Sbjct: 15 KTGVFQLTGKGLTEFPEDLQKLTANLRTVDLSNNKIEELPAFIGSFQH-LKSFTISCNKL 73 Query: 265 TSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTS 444 TSLP + L L N + L++LP +G L S Sbjct: 74 TSLPNDIGKLKKLETLIL-------------------------NGNQLKQLPSSIGQLKS 108 Query: 445 LRELDISYNSISVLPDSMGCLAKLNKFSAVGNPLICPPMDIVE 573 LR L +S N P +G L +L+ N + P ++ E Sbjct: 109 LRTLSLSGNQFKEFPSGLGTLRQLDVLDLSKNQIRVVPAEVAE 151
>LRC18_RAT (Q66HD6) Leucine-rich repeat-containing protein 18| Length = 256 Score = 64.3 bits (155), Expect = 2e-10 Identities = 38/110 (34%), Positives = 59/110 (53%), Gaps = 2/110 (1%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLL--QSLPATIEECRALEELNA 177 I++ N+ LD+ SN + LP SIG ++ L LNVS N L LP + + + + +N Sbjct: 69 ISKFQNLRWLDLHSNYIDKLPESIGQMTSLLFLNVSNNRLTTNGLPVELNQLKNIRTVNL 128 Query: 178 NFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLN 327 N L +P TLG L L + ++ N LTS+P S + L+ L+ + N Sbjct: 129 GLNHLDSVPTTLG-ALKELHEVGLHDNLLTSIPAGISKLPKLKKLNVKRN 177 Score = 44.7 bits (104), Expect = 2e-04 Identities = 25/78 (32%), Positives = 44/78 (56%) Frame = +1 Query: 10 RLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQ 189 +L N+ +++ N L S+P ++G L +L + + NLL S+PA I + L++LN N Sbjct: 119 QLKNIRTVNLGLNHLDSVPTTLGALKELHEVGLHDNLLTSIPAGISKLPKLKKLNVKRNP 178 Query: 190 LTRLPDTLGFELHSLRRL 243 + PD + S++RL Sbjct: 179 FPK-PDESDMFVDSIKRL 195 Score = 29.3 bits (64), Expect = 8.3 Identities = 15/49 (30%), Positives = 26/49 (53%) Frame = +1 Query: 400 HFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPL 546 + +R++P + +LR LD+ N I LP+S+G + L + N L Sbjct: 60 NMIRKIPDSISKFQNLRWLDLHSNYIDKLPESIGQMTSLLFLNVSNNRL 108
>LRC18_MOUSE (Q9CQ07) Leucine-rich repeat-containing protein 18 (Testis-specific| LRR protein) Length = 262 Score = 64.3 bits (155), Expect = 2e-10 Identities = 38/110 (34%), Positives = 60/110 (54%), Gaps = 2/110 (1%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLL--QSLPATIEECRALEELNA 177 IA+ N+ LD+ SN + LP SIG ++ L LNVS N L LP + + + + +N Sbjct: 69 IAKFQNLRWLDLHSNYIDKLPESIGQMTSLLFLNVSNNRLTTNGLPVELNQLKNIRTVNL 128 Query: 178 NFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLN 327 N L +P TLG L L + ++ N LT++P S + + L+ L+ + N Sbjct: 129 GLNHLDSVPTTLG-ALKELHEVGLHDNLLTTIPASIAKLPKLKKLNIKRN 177 Score = 41.2 bits (95), Expect = 0.002 Identities = 23/78 (29%), Positives = 45/78 (57%) Frame = +1 Query: 10 RLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQ 189 +L N+ +++ N L S+P ++G L +L + + NLL ++PA+I + L++LN N Sbjct: 119 QLKNIRTVNLGLNHLDSVPTTLGALKELHEVGLHDNLLTTIPASIAKLPKLKKLNIKRNP 178 Query: 190 LTRLPDTLGFELHSLRRL 243 ++ F + S++RL Sbjct: 179 FPNADESEMF-VDSIKRL 195 Score = 29.3 bits (64), Expect = 8.3 Identities = 15/49 (30%), Positives = 26/49 (53%) Frame = +1 Query: 400 HFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPL 546 + +R++P + +LR LD+ N I LP+S+G + L + N L Sbjct: 60 NMIRKIPDSIAKFQNLRWLDLHSNYIDKLPESIGQMTSLLFLNVSNNRL 108
>POPC_RALSO (Q9RBS2) Protein popC| Length = 1024 Score = 63.9 bits (154), Expect = 3e-10 Identities = 57/189 (30%), Positives = 87/189 (46%), Gaps = 1/189 (0%) Frame = +1 Query: 4 IARLLNVVVLDVRSN-QLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNAN 180 I L + L ++ N +L SLP S G LS L+ L ++GN + LP ++ +L+ L + Sbjct: 424 IGNLFTLKTLSLQDNPKLGSLPASFGQLSGLQELTLNGNRIHELP-SMGGASSLQTLTVD 482 Query: 181 FNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXX 360 L LP G L +L LS+++ +L LP +T ++ AL+ L + N Sbjct: 483 DTALAGLPADFG-ALRNLAHLSLSNTQLRELPANTGNLHALKTLSLQGN----------- 530 Query: 361 XXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGN 540 L LP LG L+ L EL + +S+S LP MG + L + + Sbjct: 531 -------------QQLATLPSSLGYLSGLEELTLKNSSVSELP-PMGPGSALKTLTVENS 576 Query: 541 PLICPPMDI 567 PL P DI Sbjct: 577 PLTSIPADI 585 Score = 45.8 bits (107), Expect = 9e-05 Identities = 55/207 (26%), Positives = 86/207 (41%), Gaps = 28/207 (13%) Frame = +1 Query: 7 ARLLNVVVLDVRS----NQLKSLPNSIGCLSKLRVLNVSGNLLQSLP----------ATI 144 A L N+ +L+ S K+LP+++ L L+ L +S L+SLP TI Sbjct: 241 ATLENLFLLETLSLKGAKNFKALPDAVWRLPALQELKLSETGLKSLPPVGGGSALQRLTI 300 Query: 145 EECRALEELNANF-------------NQLTRLPDTLGFELHSLRRLSVNSN-KLTSLPFS 282 E+ LE+L A F +L +L +G +L +L+ LS+ N KL LP S Sbjct: 301 ED-SPLEQLPAGFADLDQLASLSLSNTKLEKLSSGIG-QLPALKSLSLQDNPKLERLPKS 358 Query: 283 TSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDI 462 + L + R++ + + L +LP G L +L + + Sbjct: 359 LGQVEELTLIGGRIHALPSASGMSSLQKLTVDNSS------LAKLPADFGALGNLAHVSL 412 Query: 463 SYNSISVLPDSMGCLAKLNKFSAVGNP 543 S + LP S+G L L S NP Sbjct: 413 SNTKLRDLPASIGNLFTLKTLSLQDNP 439 Score = 36.2 bits (82), Expect = 0.068 Identities = 49/183 (26%), Positives = 76/183 (41%), Gaps = 12/183 (6%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPN--------SIGCLSKLRVLNVSGNLLQSLPATIEECRA 159 + L +V+ + S QLKSLP I L L ++ L +LPAT+E Sbjct: 192 VDHLKSVLRMSGDSVQLKSLPVPELPDVTFEIAHLKNLETVDCD---LHALPATLENLFL 248 Query: 160 LEELN-ANFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLP--FSTSHMTALRALDARLNC 330 LE L+ LPD + + L +L+ L ++ L SLP S + L D+ L Sbjct: 249 LETLSLKGAKNFKALPDAV-WRLPALQELKLSETGLKSLPPVGGGSALQRLTIEDSPLEQ 307 Query: 331 IRAXXXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYN-SISVLPDSMGCL 507 + A L +L G+G L +L+ L + N + LP S+G + Sbjct: 308 LPAGFADLDQLASLSLSNTK-----LEKLSSGIGQLPALKSLSLQDNPKLERLPKSLGQV 362 Query: 508 AKL 516 +L Sbjct: 363 EEL 365 Score = 33.1 bits (74), Expect = 0.58 Identities = 30/92 (32%), Positives = 49/92 (53%), Gaps = 8/92 (8%) Frame = +1 Query: 31 LDVRSNQLKSLPNSIGCLSKLRVLNVSGN-----LLQSLPATIEECRALEELNANFNQLT 195 L + + QL++LP+SIG LS L+ L + N L +S +E R ++ + +LT Sbjct: 595 LSLSNTQLRALPSSIGKLSNLKGLTLKNNARLELLSESGVRKLESVRKID--LSGCVRLT 652 Query: 196 RLPDTLGFELHSLRRLSVN---SNKLTSLPFS 282 LP ++G +L LR L ++ + SLP S Sbjct: 653 GLPSSIG-KLPKLRTLDLSGCTGLSMASLPRS 683
>LRC57_RAT (Q5FVI3) Leucine-rich repeat-containing protein 57| Length = 239 Score = 63.5 bits (153), Expect = 4e-10 Identities = 36/110 (32%), Positives = 64/110 (58%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 + L + L + +N L+ LP+S G LS L+ L++SGN L +LP + R L+ ++ + Sbjct: 81 LCNLKKLETLSLNNNHLRELPSSFGQLSALKTLSLSGNQLGALPPQLCSLRHLDVVDLSK 140 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCI 333 NQ+ +PDT+G EL ++ L++N N+++ + S L+ L NC+ Sbjct: 141 NQIRSIPDTVG-ELQAI-ELNLNQNQISQISVRISCCPRLKVLRLEENCL 188 Score = 49.3 bits (116), Expect = 8e-06 Identities = 34/102 (33%), Positives = 58/102 (56%), Gaps = 3/102 (2%) Frame = +1 Query: 31 LDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDT 210 L + +N+L LP+ + L KL L+++ N L+ LP++ + AL+ L+ + NQL LP Sbjct: 67 LSLNNNKLTVLPDELCNLKKLETLSLNNNHLRELPSSFGQLSALKTLSLSGNQLGALPP- 125 Query: 211 LGFELHSLRRLSV---NSNKLTSLPFSTSHMTALRALDARLN 327 +L SLR L V + N++ S+P + L+A++ LN Sbjct: 126 ---QLCSLRHLDVVDLSKNQIRSIPDTVGE---LQAIELNLN 161 Score = 46.2 bits (108), Expect = 7e-05 Identities = 42/164 (25%), Positives = 70/164 (42%), Gaps = 7/164 (4%) Frame = +1 Query: 88 KLRVLNVSGNLLQSLPATIEECRA-LEELNANFNQLTRLPDTLGFELHSLRRLSVNSNKL 264 K V + L P+ +++ + L ++ + N++ LP + + L+ LS+N+NKL Sbjct: 15 KTGVFQLKDRGLTEFPSELQKLTSNLRTIDLSNNKIDSLPPLIIGKFTLLKSLSLNNNKL 74 Query: 265 TSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTS 444 T LP ++ L L N +R S N L LP L L Sbjct: 75 TVLPDELCNLKKLETLSLNNNHLRELPSSFGQLSALKTLSLSGN--QLGALPPQLCSLRH 132 Query: 445 LRELDISYNSISVLPDSMGCLAKL------NKFSAVGNPLICPP 558 L +D+S N I +PD++G L + N+ S + + C P Sbjct: 133 LDVVDLSKNQIRSIPDTVGELQAIELNLNQNQISQISVRISCCP 176 Score = 42.7 bits (99), Expect = 7e-04 Identities = 36/132 (27%), Positives = 56/132 (42%), Gaps = 1/132 (0%) Frame = +1 Query: 127 SLPATIEECRALEELNANFNQLTRLPDTLGFELHSLRRLSVNSNKLTSL-PFSTSHMTAL 303 +L A +E + LT P L +LR + +++NK+ SL P T L Sbjct: 5 ALRAHVETAQKTGVFQLKDRGLTEFPSELQKLTSNLRTIDLSNNKIDSLPPLIIGKFTLL 64 Query: 304 RALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISV 483 ++L LN + S N + LRELP G L++L+ L +S N + Sbjct: 65 KSLS--LNNNKLTVLPDELCNLKKLETLSLNNNHLRELPSSFGQLSALKTLSLSGNQLGA 122 Query: 484 LPDSMGCLAKLN 519 LP + L L+ Sbjct: 123 LPPQLCSLRHLD 134
>LRC39_BOVIN (Q3ZC49) Leucine-rich repeat-containing protein 39| Length = 334 Score = 62.8 bits (151), Expect = 7e-10 Identities = 48/182 (26%), Positives = 84/182 (46%), Gaps = 1/182 (0%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 I R N++VLD+ N + +P IG L++L+ L +S N ++++P + C +LE+L Sbjct: 102 IGRFQNLIVLDLSRNTITEIPRGIGLLTRLQELILSYNRIKTVPMELSYCASLEKLELAV 161 Query: 184 NQ-LTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXX 360 N+ ++ LP L L L L ++ N T++P + +M AL LD N Sbjct: 162 NRDISDLPQELS-NLLKLTHLDLSMNLFTTIPPAVLNMPALEWLDMGSNR---------- 210 Query: 361 XXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGN 540 L +LP + + +L L + N I+ LP+++ + L+ N Sbjct: 211 ---------------LEQLPDTIERMQNLHTLWLQRNEITCLPETISSMKNLSTLVLSNN 255 Query: 541 PL 546 L Sbjct: 256 KL 257 Score = 56.2 bits (134), Expect = 6e-08 Identities = 34/111 (30%), Positives = 61/111 (54%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 ++ LL + LD+ N ++P ++ + L L++ N L+ LP TIE + L L Sbjct: 172 LSNLLKLTHLDLSMNLFTTIPPAVLNMPALEWLDMGSNRLEQLPDTIERMQNLHTLWLQR 231 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIR 336 N++T LP+T+ + +L L +++NKL +P MT LR ++ R N ++ Sbjct: 232 NEITCLPETIS-SMKNLSTLVLSNNKLQDIPVCMEKMTNLRFVNFRDNPLK 281 Score = 48.9 bits (115), Expect = 1e-05 Identities = 30/90 (33%), Positives = 48/90 (53%) Frame = +1 Query: 43 SNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDTLGFE 222 + + LP + L KL L++S NL ++P + ALE L+ N+L +LPDT+ Sbjct: 162 NRDISDLPQELSNLLKLTHLDLSMNLFTTIPPAVLNMPALEWLDMGSNRLEQLPDTIE-R 220 Query: 223 LHSLRRLSVNSNKLTSLPFSTSHMTALRAL 312 + +L L + N++T LP + S M L L Sbjct: 221 MQNLHTLWLQRNEITCLPETISSMKNLSTL 250 Score = 30.8 bits (68), Expect = 2.9 Identities = 16/54 (29%), Positives = 30/54 (55%) Frame = +1 Query: 406 LRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPLICPPMDI 567 L ++P +G +L LD+S N+I+ +P +G L +L + N + PM++ Sbjct: 95 LLKIPEFIGRFQNLIVLDLSRNTITEIPRGIGLLTRLQELILSYNRIKTVPMEL 148
>LRCH4_MOUSE (Q921G6) Leucine-rich repeats and calponin homology| domain-containing protein 4 Length = 680 Score = 62.8 bits (151), Expect = 7e-10 Identities = 39/95 (41%), Positives = 57/95 (60%) Frame = +1 Query: 28 VLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPD 207 VL + +N+L +LP I L LR L+VS N LQSLP + R+L +LN NQL+ LPD Sbjct: 140 VLIISNNKLGALPPDISTLGSLRQLDVSSNELQSLPVELCSLRSLRDLNVRRNQLSTLPD 199 Query: 208 TLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRAL 312 LG +L L RL + N+++ +P S + L+ + Sbjct: 200 ELG-DL-PLVRLDFSCNRISRIPVSFCRLRHLQVV 232 Score = 62.8 bits (151), Expect = 7e-10 Identities = 64/186 (34%), Positives = 85/186 (45%) Frame = +1 Query: 10 RLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQ 189 +L+++ L + N LK L ++G L+ L LN+S N L SLP I + L L + N+ Sbjct: 89 QLVSLEGLSLYHNCLKCLNPALGNLTALTYLNLSRNQLSSLPPYICQL-PLRVLIISNNK 147 Query: 190 LTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXX 369 L LP + L SLR+L V+SN+L SLP + +LR L+ R N Sbjct: 148 LGALPPDIS-TLGSLRQLDVSSNELQSLPVELCSLRSLRDLNVRRNQ------------- 193 Query: 370 XXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPLI 549 L LP LG L +R LD S N IS +P S L L NPL Sbjct: 194 ------------LSTLPDELGDLPLVR-LDFSCNRISRIPVSFCRLRHLQVVLLDSNPLQ 240 Query: 550 CPPMDI 567 PP I Sbjct: 241 SPPAQI 246 Score = 57.0 bits (136), Expect = 4e-08 Identities = 50/165 (30%), Positives = 76/165 (46%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQL 192 L ++ D+ N+ +P + L L L++ N L+ L + AL LN + NQL Sbjct: 67 LSDITQADLSRNRFPEVPEAACQLVSLEGLSLYHNCLKCLNPALGNLTALTYLNLSRNQL 126 Query: 193 TRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXX 372 + LP + +L LR L +++NKL +LP S + +LR LD N Sbjct: 127 SSLPPYI-CQL-PLRVLIISNNKLGALPPDISTLGSLRQLDVSSN--------------- 169 Query: 373 XXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCL 507 L+ LP L L SLR+L++ N +S LPD +G L Sbjct: 170 ----------ELQSLPVELCSLRSLRDLNVRRNQLSTLPDELGDL 204 Score = 44.7 bits (104), Expect = 2e-04 Identities = 33/91 (36%), Positives = 53/91 (58%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 I+ L ++ LDV SN+L+SLP + L LR LNV N L +LP + + L L+ + Sbjct: 155 ISTLGSLRQLDVSSNELQSLPVELCSLRSLRDLNVRRNQLSTLPDELGDL-PLVRLDFSC 213 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTSLP 276 N+++R+P + L L+ + ++SN L S P Sbjct: 214 NRISRIPVSF-CRLRHLQVVLLDSNPLQSPP 243 Score = 37.7 bits (86), Expect = 0.023 Identities = 35/170 (20%), Positives = 62/170 (36%), Gaps = 22/170 (12%) Frame = +1 Query: 124 QSLPATIEECRALEELNANFNQLTRLPD--TLGFELHSLRRLSVNSNKLTSLPFSTSHMT 297 +S +EE A LN + +L P ++L + + ++ N+ +P + + Sbjct: 32 RSAERALEEAVATGTLNLSNRRLKHFPRGAARSYDLSDITQADLSRNRFPEVPEAACQLV 91 Query: 298 ALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNF--------------------HFLREL 417 +L L NC++ S+N + L L Sbjct: 92 SLEGLSLYHNCLKCLNPALGNLTALTYLNLSRNQLSSLPPYICQLPLRVLIISNNKLGAL 151 Query: 418 PYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPLICPPMDI 567 P + L SLR+LD+S N + LP + L L + N L P ++ Sbjct: 152 PPDISTLGSLRQLDVSSNELQSLPVELCSLRSLRDLNVRRNQLSTLPDEL 201
>CYAA_YEAST (P08678) Adenylate cyclase (EC 4.6.1.1) (ATP pyrophosphate-lyase)| (Adenylyl cyclase) Length = 2026 Score = 62.4 bits (150), Expect = 9e-10 Identities = 46/171 (26%), Positives = 83/171 (48%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 I + +V L+++ N ++ +PNSI LS L +LN+ N L+SLPA E + L+ L+ + Sbjct: 859 ITKAYKLVSLELQRNFIRKVPNSIMKLSNLTILNLQCNELESLPAGFVELKNLQLLDLSS 918 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXX 363 N+ P+ + + +L ++ ++ NK+ SLP ST ++ L ++ N Sbjct: 919 NKFMHYPEVINY-CTNLLQIDLSYNKIQSLPQSTKYLVKLAKMNLSHN------------ 965 Query: 364 XXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKL 516 +F+ + L +T LR L++ YN IS + + L L Sbjct: 966 ----------KLNFIGD----LSEMTDLRTLNLRYNRISSIKTNASNLQNL 1002 Score = 47.0 bits (110), Expect = 4e-05 Identities = 48/177 (27%), Positives = 79/177 (44%), Gaps = 5/177 (2%) Frame = +1 Query: 31 LDVRSNQ-----LKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLT 195 LDV +N L+ + +SI LS LR++N+ + P+ I + L L N + Sbjct: 821 LDVSNNANIFLPLEFIESSIKLLS-LRMVNIRAS---KFPSNITKAYKLVSLELQRNFIR 876 Query: 196 RLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXX 375 ++P+++ +L +L L++ N+L SLP + L+ LD N Sbjct: 877 KVPNSI-MKLSNLTILNLQCNELESLPAGFVELKNLQLLDLSSN---------------- 919 Query: 376 XXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPL 546 + H+ P + T+L ++D+SYN I LP S L KL K + N L Sbjct: 920 -----KFMHY----PEVINYCTNLLQIDLSYNKIQSLPQSTKYLVKLAKMNLSHNKL 967 Score = 44.7 bits (104), Expect = 2e-04 Identities = 33/85 (38%), Positives = 44/85 (51%) Frame = +1 Query: 82 LSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDTLGFELHSLRRLSVNSNK 261 L+K ++ ++ G LL L LE+L N N LTRLP + +L L LSV NK Sbjct: 1047 LNKAQLSSIPGELLTKLSF-------LEKLELNQNNLTRLPQEIS-KLTKLVFLSVARNK 1098 Query: 262 LTSLPFSTSHMTALRALDARLNCIR 336 L +P S + +LR LD N IR Sbjct: 1099 LEYIPPELSQLKSLRTLDLHSNNIR 1123 Score = 43.1 bits (100), Expect = 6e-04 Identities = 40/139 (28%), Positives = 54/139 (38%) Frame = +1 Query: 82 LSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDTLGFELHSLRRLSVNSNK 261 L KLR L + N + S+ + + L N QL+ +P L +L L +L +N N Sbjct: 1016 LPKLRALEIQENPITSISFKDFYPKNMTSLTLNKAQLSSIPGELLTKLSFLEKLELNQNN 1075 Query: 262 LTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLT 441 LT LP S +T L L N L +P L L Sbjct: 1076 LTRLPQEISKLTKLVFLSVARNK-------------------------LEYIPPELSQLK 1110 Query: 442 SLRELDISYNSISVLPDSM 498 SLR LD+ N+I D M Sbjct: 1111 SLRTLDLHSNNIRDFVDGM 1129 Score = 41.2 bits (95), Expect = 0.002 Identities = 26/86 (30%), Positives = 44/86 (51%) Frame = +1 Query: 79 CLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDTLGFELHSLRRLSVNSN 258 C L+VLN+S N + + ++ EL + N+LT L + SL+ L +NSN Sbjct: 1187 CFVNLKVLNLSYNNFSDVSHM--KLESITELYLSGNKLTTLSGDTVLKWSSLKTLMLNSN 1244 Query: 259 KLTSLPFSTSHMTALRALDARLNCIR 336 ++ SLP S+++ L D N ++ Sbjct: 1245 QMLSLPAELSNLSQLSVFDVGANQLK 1270
>LRC57_MOUSE (Q9D1G5) Leucine-rich repeat-containing protein 57| Length = 239 Score = 62.0 bits (149), Expect = 1e-09 Identities = 36/110 (32%), Positives = 64/110 (58%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 + L + L + +N L+ LP++ G LS L+ L++SGN L +LP + R L+ ++ + Sbjct: 81 LCNLKKLETLSLNNNHLRELPSTFGQLSALKTLSLSGNQLGALPPQLCCLRHLDVVDLSK 140 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCI 333 NQ+ +PDT+G EL ++ L++N N+++ L S L+ L NC+ Sbjct: 141 NQIRSIPDTVG-ELQAI-ELNLNQNQISQLSVKISCCPRLKVLRLEENCL 188 Score = 56.6 bits (135), Expect = 5e-08 Identities = 54/185 (29%), Positives = 82/185 (44%), Gaps = 8/185 (4%) Frame = +1 Query: 28 VLDVRSNQLKSLPNSIGCL-SKLRVLNVSGNLLQSLPATI-EECRALEELNANFNQLTRL 201 V ++ L P+ + L S LR +++S N + SLP I + L+ L+ N N+LT L Sbjct: 18 VFQLKDRGLTEFPSELQKLTSNLRTIDLSNNKIDSLPPLIIGKFTLLKSLSLNNNKLTVL 77 Query: 202 PDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXX 381 PD L L L LS+N+N L LP + ++AL+ L N + A Sbjct: 78 PDEL-CNLKKLETLSLNNNHLRELPSTFGQLSALKTLSLSGNQLGA-------------- 122 Query: 382 XXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKL------NKFSAVGNP 543 LP L L L +D+S N I +PD++G L + N+ S + Sbjct: 123 -----------LPPQLCCLRHLDVVDLSKNQIRSIPDTVGELQAIELNLNQNQISQLSVK 171 Query: 544 LICPP 558 + C P Sbjct: 172 ISCCP 176 Score = 48.5 bits (114), Expect = 1e-05 Identities = 38/145 (26%), Positives = 64/145 (44%), Gaps = 1/145 (0%) Frame = +1 Query: 88 KLRVLNVSGNLLQSLPATIEECRA-LEELNANFNQLTRLPDTLGFELHSLRRLSVNSNKL 264 K V + L P+ +++ + L ++ + N++ LP + + L+ LS+N+NKL Sbjct: 15 KTGVFQLKDRGLTEFPSELQKLTSNLRTIDLSNNKIDSLPPLIIGKFTLLKSLSLNNNKL 74 Query: 265 TSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTS 444 T LP ++ L L S N + LRELP G L++ Sbjct: 75 TVLPDELCNLKKLETL-------------------------SLNNNHLRELPSTFGQLSA 109 Query: 445 LRELDISYNSISVLPDSMGCLAKLN 519 L+ L +S N + LP + CL L+ Sbjct: 110 LKTLSLSGNQLGALPPQLCCLRHLD 134
>LRCH4_HUMAN (O75427) Leucine-rich repeats and calponin homology| domain-containing protein 4 (Leucine-rich neuronal protein) Length = 683 Score = 62.0 bits (149), Expect = 1e-09 Identities = 61/186 (32%), Positives = 86/186 (46%) Frame = +1 Query: 10 RLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQ 189 +L+++ L + N L+ L ++G L+ L LN+S N L LP I + L L + N+ Sbjct: 89 QLVSLEGLSLYHNCLRCLNPALGNLTALTYLNLSRNQLSLLPPYICQL-PLRVLIVSNNK 147 Query: 190 LTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXX 369 L LP +G L SLR+L V+SN+L SLP +++LR L+ R N Sbjct: 148 LGALPPDIG-TLGSLRQLDVSSNELQSLPSELCGLSSLRDLNVRRNQ------------- 193 Query: 370 XXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPLI 549 L LP LG L +R LD S N +S +P S L L NPL Sbjct: 194 ------------LSTLPEELGDLPLVR-LDFSCNRVSRIPVSFCRLRHLQVILLDSNPLQ 240 Query: 550 CPPMDI 567 PP + Sbjct: 241 SPPAQV 246 Score = 61.2 bits (147), Expect = 2e-09 Identities = 39/95 (41%), Positives = 58/95 (61%) Frame = +1 Query: 28 VLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPD 207 VL V +N+L +LP IG L LR L+VS N LQSLP+ + +L +LN NQL+ LP+ Sbjct: 140 VLIVSNNKLGALPPDIGTLGSLRQLDVSSNELQSLPSELCGLSSLRDLNVRRNQLSTLPE 199 Query: 208 TLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRAL 312 LG +L L RL + N+++ +P S + L+ + Sbjct: 200 ELG-DL-PLVRLDFSCNRVSRIPVSFCRLRHLQVI 232 Score = 53.5 bits (127), Expect = 4e-07 Identities = 49/165 (29%), Positives = 76/165 (46%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQL 192 L ++ D+ N+ +P + L L L++ N L+ L + AL LN + NQL Sbjct: 67 LSDITQADLSRNRFPEVPEAACQLVSLEGLSLYHNCLRCLNPALGNLTALTYLNLSRNQL 126 Query: 193 TRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXX 372 + LP + +L LR L V++NKL +LP + +LR LD N Sbjct: 127 SLLPPYI-CQL-PLRVLIVSNNKLGALPPDIGTLGSLRQLDVSSN--------------- 169 Query: 373 XXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCL 507 L+ LP L L+SLR+L++ N +S LP+ +G L Sbjct: 170 ----------ELQSLPSELCGLSSLRDLNVRRNQLSTLPEELGDL 204 Score = 42.7 bits (99), Expect = 7e-04 Identities = 37/170 (21%), Positives = 64/170 (37%), Gaps = 22/170 (12%) Frame = +1 Query: 124 QSLPATIEECRALEELNANFNQLTRLPD--TLGFELHSLRRLSVNSNKLTSLPFSTSHMT 297 +S +EE A LN + +L P ++L + + ++ N+ +P + + Sbjct: 32 RSAERALEEAVATGTLNLSNRRLKHFPRGAARSYDLSDITQADLSRNRFPEVPEAACQLV 91 Query: 298 ALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNF--------------------HFLREL 417 +L L NC+R S+N + L L Sbjct: 92 SLEGLSLYHNCLRCLNPALGNLTALTYLNLSRNQLSLLPPYICQLPLRVLIVSNNKLGAL 151 Query: 418 PYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPLICPPMDI 567 P +G L SLR+LD+S N + LP + L+ L + N L P ++ Sbjct: 152 PPDIGTLGSLRQLDVSSNELQSLPSELCGLSSLRDLNVRRNQLSTLPEEL 201
>LGR4_RAT (Q9Z2H4) Leucine-rich repeat-containing G-protein coupled receptor| 4 precursor Length = 951 Score = 62.0 bits (149), Expect = 1e-09 Identities = 54/185 (29%), Positives = 94/185 (50%), Gaps = 4/185 (2%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPN-SIGCLSKLRVLNVSGNLLQSLPA-TIEECRALEELNA 177 ++ L + VL +++NQL+++P+ +I LS L+ L + N + S+P + E L L Sbjct: 101 LSGLKELKVLTLQNNQLRTVPSEAIHGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWL 160 Query: 178 NFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLP-FSTSHMTALRALDARLNCIRAXXXXX 354 + N LT +P L +L+ L++ N ++S+P F+ +++++L L N I++ Sbjct: 161 DDNSLTEVPVRPLSNLPTLQALTLALNNISSIPDFAFTNLSSLVVLHLHNNKIKSLSQHC 220 Query: 355 XXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPD-SMGCLAKLNKFSA 531 N+++L E P + L SL+EL NSISV+PD + G L Sbjct: 221 FDGLDNLETL-DLNYNYLDEFPQAIKALPSLKELGFHSNSISVIPDGAFGGNPLLRTIHL 279 Query: 532 VGNPL 546 NPL Sbjct: 280 YDNPL 284 Score = 53.9 bits (128), Expect = 3e-07 Identities = 45/179 (25%), Positives = 77/179 (43%), Gaps = 3/179 (1%) Frame = +1 Query: 31 LDVRSNQLKSL-PNSIGCLSKLRVLNVSGNLLQSLPA-TIEECRALEELNANFNQLTRLP 204 L + N L + P ++ L +L+VL + N L+++P+ I AL+ L + N +T +P Sbjct: 86 LQLAGNDLSLIHPKALSGLKELKVLTLQNNQLRTVPSEAIHGLSALQSLRLDANHITSVP 145 Query: 205 DTLGFELHSLRRLSVNSNKLTSLPFST-SHMTALRALDARLNCIRAXXXXXXXXXXXXXX 381 + L LR L ++ N LT +P S++ L+AL LN I + Sbjct: 146 EDSFEGLVQLRHLWLDDNSLTEVPVRPLSNLPTLQALTLALNNISSIPDFAFTNLSSLVV 205 Query: 382 XXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPLICPP 558 N + L +L LD++YN + P ++ L L + N + P Sbjct: 206 LHLHNNKIKSLSQHCFDGLDNLETLDLNYNYLDEFPQAIKALPSLKELGFHSNSISVIP 264 Score = 38.1 bits (87), Expect = 0.018 Identities = 25/82 (30%), Positives = 46/82 (56%), Gaps = 1/82 (1%) Frame = +1 Query: 31 LDVRSNQLKSLPNSIGCLSK-LRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPD 207 L + ++ S+P+ + K LR L++S N ++ LP+ CRALEE++ NQ++ + + Sbjct: 324 LTLTGTKISSIPDDLCQNQKMLRTLDLSYNNIRDLPS-FNGCRALEEISLQRNQISLIKE 382 Query: 208 TLGFELHSLRRLSVNSNKLTSL 273 L SLR L ++ N + + Sbjct: 383 NTFQGLTSLRILDLSRNLIREI 404
>RLK5_ARATH (P47735) Receptor-like protein kinase 5 precursor (EC 2.7.11.1)| Length = 999 Score = 61.6 bits (148), Expect = 2e-09 Identities = 49/172 (28%), Positives = 81/172 (47%), Gaps = 7/172 (4%) Frame = +1 Query: 13 LLNVVVLDVRSNQLK-SLPNSIGCLSKLRVLNVSGNLLQ-SLPATIEECRALEELNANFN 186 L N+ L++ N L ++P+S G KL LN++GN L ++PA++ L+EL +N Sbjct: 138 LPNLKFLEISGNNLSDTIPSSFGEFRKLESLNLAGNFLSGTIPASLGNVTTLKELKLAYN 197 Query: 187 QLTRLPDTLGFELHSLRRLSV----NSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXX 354 + P + +L +L L V N + +P S S +T+L LD N + Sbjct: 198 LFS--PSQIPSQLGNLTELQVLWLAGCNLVGPIPPSLSRLTSLVNLDLTFNQLTGSIPSW 255 Query: 355 XXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSIS-VLPDSMGCL 507 N F ELP +G +T+L+ D S N ++ +PD++ L Sbjct: 256 ITQLKTVEQIELFNNSFSGELPESMGNMTTLKRFDASMNKLTGKIPDNLNLL 307 Score = 45.4 bits (106), Expect = 1e-04 Identities = 40/166 (24%), Positives = 70/166 (42%), Gaps = 26/166 (15%) Frame = +1 Query: 61 LPNSIGCLSKLRVLNVSG-NLLQSLPATIEECRALEELNANFNQLT-------------- 195 +P+ +G L++L+VL ++G NL+ +P ++ +L L+ FNQLT Sbjct: 204 IPSQLGNLTELQVLWLAGCNLVGPIPPSLSRLTSLVNLDLTFNQLTGSIPSWITQLKTVE 263 Query: 196 -----------RLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAX 342 LP+++G + +L+R + NKLT ++ L +L+ N + Sbjct: 264 QIELFNNSFSGELPESMG-NMTTLKRFDASMNKLTGKIPDNLNLLNLESLNLFENMLEGP 322 Query: 343 XXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSIS 480 N LP LG + L+ +D+SYN S Sbjct: 323 LPESITRSKTLSELKLFNNRLTGVLPSQLGANSPLQYVDLSYNRFS 368 Score = 36.6 bits (83), Expect = 0.052 Identities = 36/143 (25%), Positives = 60/143 (41%), Gaps = 3/143 (2%) Frame = +1 Query: 61 LPNSIGCLSKLRVLNVSGNLLQ-SLPATIEECRALEELNANFNQLT-RLPDTLGFELHSL 234 +P+ L +L +L +S N S+P TI + L L + N+ + +P+ +G L+ + Sbjct: 419 IPHGFWGLPRLSLLELSDNSFTGSIPKTIIGAKNLSNLRISKNRFSGSIPNEIG-SLNGI 477 Query: 235 RRLSVNSNKLTS-LPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHFLR 411 +S N + +P S + L LD N + N H Sbjct: 478 IEISGAENDFSGEIPESLVKLKQLSRLDLSKNQLSGEIPRELRGWKNLNELNLANNHLSG 537 Query: 412 ELPYGLGLLTSLRELDISYNSIS 480 E+P +G+L L LD+S N S Sbjct: 538 EIPKEVGILPVLNYLDLSSNQFS 560
>LRC18_HUMAN (Q8N456) Leucine-rich repeat-containing protein 18| Length = 261 Score = 61.2 bits (147), Expect = 2e-09 Identities = 37/110 (33%), Positives = 60/110 (54%), Gaps = 2/110 (1%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQS--LPATIEECRALEELNA 177 I++ N+ LD+ SN + LP SIG ++ L LNVS N L S LP +++ + + +N Sbjct: 69 ISKFQNLRWLDLHSNYIDKLPESIGQMTSLLYLNVSNNRLTSNGLPVELKQLKNIRAVNL 128 Query: 178 NFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLN 327 N L + TLG L L + ++ N L ++P S S + L+ L+ + N Sbjct: 129 GLNHLDSVSTTLG-ALKELHEVGLHDNLLNNIPVSISKLPKLKKLNIKRN 177 Score = 58.9 bits (141), Expect = 1e-08 Identities = 48/177 (27%), Positives = 85/177 (48%), Gaps = 2/177 (1%) Frame = +1 Query: 31 LDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDT 210 LD+ + + P I LS + L++S NL++ +P +I + + L L+ + N + +LP++ Sbjct: 32 LDLSKMGITTFPKCILRLSDMDELDLSRNLIRKIPDSISKFQNLRWLDLHSNYIDKLPES 91 Query: 211 LGFELHSLRRLSVNSNKLTS--LPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXX 384 +G ++ SL L+V++N+LTS LP + +RA++ LN Sbjct: 92 IG-QMTSLLYLNVSNNRLTSNGLPVELKQLKNIRAVNLGLN------------------- 131 Query: 385 XSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPLICP 555 L + LG L L E+ + N ++ +P S+ L KL K + NP P Sbjct: 132 ------HLDSVSTTLGALKELHEVGLHDNLLNNIPVSISKLPKLKKLNIKRNPFPKP 182
>LRC8D_MOUSE (Q8BGR2) Leucine-rich repeat-containing protein 8D| Length = 859 Score = 61.2 bits (147), Expect = 2e-09 Identities = 38/110 (34%), Positives = 62/110 (56%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 I + N+ L +N+L+SLP ++ L KLR L+VS N + ++P I + L+ L+ Sbjct: 703 ITHVKNLESLYFSNNKLESLPTAVFSLQKLRCLDVSYNNISTIPIEIGLLQNLQHLHITG 762 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCI 333 N++ LP L F+ LR L++ N + SLP S +T L L+ + NC+ Sbjct: 763 NKVDILPKQL-FKCVKLRTLNLGQNCIASLPEKISQLTQLTQLELKGNCL 811 Score = 56.6 bits (135), Expect = 5e-08 Identities = 45/190 (23%), Positives = 88/190 (46%), Gaps = 2/190 (1%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATI--EECRALEELNA 177 + +++NV L++++ +L+ +P++I LS L+ L++ N ++++ I + + L L Sbjct: 632 LKKMMNVAELELQNCELERIPHAIFSLSNLQELDLKSNNIRTIEEIISFQHLKRLTCLKL 691 Query: 178 NFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXX 357 N++ +P ++ + +L L ++NKL SLP + + LR LD N I Sbjct: 692 WHNKIVAIPPSIT-HVKNLESLYFSNNKLESLPTAVFSLQKLRCLDVSYNNIST------ 744 Query: 358 XXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVG 537 +P +GLL +L+ L I+ N + +LP + KL + Sbjct: 745 -------------------IPIEIGLLQNLQHLHITGNKVDILPKQLFKCVKLRTLNLGQ 785 Query: 538 NPLICPPMDI 567 N + P I Sbjct: 786 NCIASLPEKI 795 Score = 52.8 bits (125), Expect = 7e-07 Identities = 54/194 (27%), Positives = 87/194 (44%), Gaps = 6/194 (3%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGC----LSKLRVLNVSGNLLQSLPATIEECRALEEL 171 + L ++ +L V+SN L +P++I L+KL + N LL + ++++ + EL Sbjct: 585 LRELRHLKILHVKSN-LTKVPSNITDVAPHLTKLVIHNDGTKLL--VLNSLKKMMNVAEL 641 Query: 172 NANFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLP--FSTSHMTALRALDARLNCIRAXX 345 +L R+P + F L +L+ L + SN + ++ S H+ L L N I A Sbjct: 642 ELQNCELERIPHAI-FSLSNLQELDLKSNNIRTIEEIISFQHLKRLTCLKLWHNKIVAIP 700 Query: 346 XXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKF 525 S N L LP + L LR LD+SYN+IS +P +G L L Sbjct: 701 PSITHVKNLESLYFSNNK--LESLPTAVFSLQKLRCLDVSYNNISTIPIEIGLLQNLQHL 758 Query: 526 SAVGNPLICPPMDI 567 GN + P + Sbjct: 759 HITGNKVDILPKQL 772 Score = 49.7 bits (117), Expect = 6e-06 Identities = 28/82 (34%), Positives = 44/82 (53%) Frame = +1 Query: 31 LDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDT 210 LDV N + ++P IG L L+ L+++GN + LP + +C L LN N + LP+ Sbjct: 735 LDVSYNNISTIPIEIGLLQNLQHLHITGNKVDILPKQLFKCVKLRTLNLGQNCIASLPEK 794 Query: 211 LGFELHSLRRLSVNSNKLTSLP 276 + +L L +L + N L LP Sbjct: 795 IS-QLTQLTQLELKGNCLDRLP 815 Score = 42.7 bits (99), Expect = 7e-04 Identities = 26/71 (36%), Positives = 35/71 (49%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 I L N+ L + N++ LP + KLR LN+ N + SLP I + L +L Sbjct: 749 IGLLQNLQHLHITGNKVDILPKQLFKCVKLRTLNLGQNCIASLPEKISQLTQLTQLELKG 808 Query: 184 NQLTRLPDTLG 216 N L RLP LG Sbjct: 809 NCLDRLPAQLG 819 Score = 38.9 bits (89), Expect = 0.010 Identities = 25/74 (33%), Positives = 37/74 (50%) Frame = +1 Query: 31 LDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDT 210 L++ N + SLP I L++L L + GN L LPA + +CR L++ +L DT Sbjct: 781 LNLGQNCIASLPEKISQLTQLTQLELKGNCLDRLPAQLGQCRMLKKSGLVVED--QLFDT 838 Query: 211 LGFELHSLRRLSVN 252 L E+ VN Sbjct: 839 LPLEVKEALNQDVN 852
>LRC57_HUMAN (Q8N9N7) Leucine-rich repeat-containing protein 57| Length = 239 Score = 60.8 bits (146), Expect = 3e-09 Identities = 35/110 (31%), Positives = 63/110 (57%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 I L + L + +N L+ LP++ G LS L+ L++SGN L +LP + R L+ ++ + Sbjct: 81 ICNLKKLETLSLNNNHLRELPSTFGQLSALKTLSLSGNQLGALPPQLCSLRHLDVMDLSK 140 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCI 333 NQ+ +PD++G EL + L++N N+++ + S L+ L NC+ Sbjct: 141 NQIRSIPDSVG-ELQVI-ELNLNQNQISQISVKISCCPRLKILRLEENCL 188 Score = 51.2 bits (121), Expect = 2e-06 Identities = 36/102 (35%), Positives = 57/102 (55%), Gaps = 3/102 (2%) Frame = +1 Query: 31 LDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDT 210 L + +N+L LP+ I L KL L+++ N L+ LP+T + AL+ L+ + NQL LP Sbjct: 67 LSLNNNKLTVLPDEICNLKKLETLSLNNNHLRELPSTFGQLSALKTLSLSGNQLGALPP- 125 Query: 211 LGFELHSLRRLSV---NSNKLTSLPFSTSHMTALRALDARLN 327 +L SLR L V + N++ S+P S L+ ++ LN Sbjct: 126 ---QLCSLRHLDVMDLSKNQIRSIPDSVGE---LQVIELNLN 161 Score = 49.7 bits (117), Expect = 6e-06 Identities = 45/164 (27%), Positives = 70/164 (42%), Gaps = 7/164 (4%) Frame = +1 Query: 88 KLRVLNVSGNLLQSLPATIEECRA-LEELNANFNQLTRLPDTLGFELHSLRRLSVNSNKL 264 K V + L PA +++ + L ++ + N++ LP L + L+ LS+N+NKL Sbjct: 15 KTGVFQLKDRGLTEFPADLQKLTSNLRTIDLSNNKIESLPPLLIGKFTLLKSLSLNNNKL 74 Query: 265 TSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTS 444 T LP ++ L L N +R S N L LP L L Sbjct: 75 TVLPDEICNLKKLETLSLNNNHLRELPSTFGQLSALKTLSLSGN--QLGALPPQLCSLRH 132 Query: 445 LRELDISYNSISVLPDSMGCLAKL------NKFSAVGNPLICPP 558 L +D+S N I +PDS+G L + N+ S + + C P Sbjct: 133 LDVMDLSKNQIRSIPDSVGELQVIELNLNQNQISQISVKISCCP 176 Score = 42.0 bits (97), Expect = 0.001 Identities = 39/150 (26%), Positives = 61/150 (40%), Gaps = 1/150 (0%) Frame = +1 Query: 127 SLPATIEECRALEELNANFNQLTRLPDTLGFELHSLRRLSVNSNKLTSL-PFSTSHMTAL 303 +L A +E + LT P L +LR + +++NK+ SL P T L Sbjct: 5 ALRAHVETAQKTGVFQLKDRGLTEFPADLQKLTSNLRTIDLSNNKIESLPPLLIGKFTLL 64 Query: 304 RALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISV 483 ++L LN + S N + LRELP G L++L+ L +S N + Sbjct: 65 KSLS--LNNNKLTVLPDEICNLKKLETLSLNNNHLRELPSTFGQLSALKTLSLSGNQLGA 122 Query: 484 LPDSMGCLAKLNKFSAVGNPLICPPMDIVE 573 LP + L L+ N + P + E Sbjct: 123 LPPQLCSLRHLDVMDLSKNQIRSIPDSVGE 152 Score = 30.4 bits (67), Expect = 3.7 Identities = 19/78 (24%), Positives = 39/78 (50%), Gaps = 4/78 (5%) Frame = +1 Query: 16 LNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQ--SLPATI--EECRALEELNANF 183 L V+ L++ NQ+ + I C +L++L + N L+ LP +I + L + N Sbjct: 153 LQVIELNLNQNQISQISVKISCCPRLKILRLEENCLELSMLPQSILSDSQICLLAVEGNL 212 Query: 184 NQLTRLPDTLGFELHSLR 237 ++ +L + G++ + R Sbjct: 213 FEIKKLRELEGYDKYMER 230
>LRCH1_HUMAN (Q9Y2L9) Leucine-rich repeats and calponin homology| domain-containing protein 1 (Calponin homology domain-containing protein 1) (Neuronal protein 81) (NP81) Length = 728 Score = 60.8 bits (146), Expect = 3e-09 Identities = 54/189 (28%), Positives = 88/189 (46%), Gaps = 1/189 (0%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRA-LEELNAN 180 + +++ +L++ N ++ +P +I L L LN+S N L +LPA + C L+ L A+ Sbjct: 116 LCHFVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQLSALPACL--CGLPLKVLIAS 173 Query: 181 FNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXX 360 N+L LP+ +G +L L L V+ N++T+LP + +LR L+ R N Sbjct: 174 NNKLGSLPEEIG-QLKQLMELDVSCNEITALPQQIGQLKSLRELNVRRN----------- 221 Query: 361 XXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGN 540 +L+ LP L L L + D S N + V+P + +L N Sbjct: 222 --------------YLKVLPQELVDLP-LVKFDFSCNKVLVIPICFREMKQLQVLLLENN 266 Query: 541 PLICPPMDI 567 PL PP I Sbjct: 267 PLQSPPAQI 275 Score = 58.9 bits (141), Expect = 1e-08 Identities = 55/184 (29%), Positives = 80/184 (43%), Gaps = 1/184 (0%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQL 192 L + V D+ N+L +P + L +LN+ N ++ +P I + L LN + NQL Sbjct: 96 LSDTVQADLSKNRLVEVPMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQL 155 Query: 193 TRLPDTL-GFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXX 369 + LP L G L+ L ++NKL SLP + L LD N I A Sbjct: 156 SALPACLCGL---PLKVLIASNNKLGSLPEEIGQLKQLMELDVSCNEITA---------- 202 Query: 370 XXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPLI 549 LP +G L SLREL++ N + VLP + L L KF N ++ Sbjct: 203 ---------------LPQQIGQLKSLRELNVRRNYLKVLPQELVDL-PLVKFDFSCNKVL 246 Query: 550 CPPM 561 P+ Sbjct: 247 VIPI 250 Score = 52.4 bits (124), Expect = 9e-07 Identities = 44/174 (25%), Positives = 67/174 (38%), Gaps = 22/174 (12%) Frame = +1 Query: 118 LLQSLPATIEECRALEELNANFNQLTRLPDTL--GFELHSLRRLSVNSNKLTSLPFSTSH 291 L + L +EE LN + +L P T G +L + ++ N+L +P H Sbjct: 59 LNRGLERALEEAANSGGLNLSARKLKEFPRTAAPGHDLSDTVQADLSKNRLVEVPMELCH 118 Query: 292 MTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQN--------------------FHFLR 411 +L L+ NCIR S+N + L Sbjct: 119 FVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQLSALPACLCGLPLKVLIASNNKLG 178 Query: 412 ELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPLICPPMDIVE 573 LP +G L L ELD+S N I+ LP +G L L + + N L P ++V+ Sbjct: 179 SLPEEIGQLKQLMELDVSCNEITALPQQIGQLKSLRELNVRRNYLKVLPQELVD 232
>LRC8E_MOUSE (Q66JT1) Leucine-rich repeat-containing protein 8E| Length = 795 Score = 60.8 bits (146), Expect = 3e-09 Identities = 49/157 (31%), Positives = 74/157 (47%), Gaps = 2/157 (1%) Frame = +1 Query: 52 LKSLPNSIGCLSKLRVLNVSGNLLQSLPATI--EECRALEELNANFNQLTRLPDTLGFEL 225 L+ +P++I L L+ L++ N L+S+ + + CR L L NQ+ +P+ + +L Sbjct: 593 LERIPHAIFSLGALQELDLKDNHLRSIEEILSFQHCRKLVTLRLWHNQIAYVPEHVR-KL 651 Query: 226 HSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHF 405 SL +L ++ NKL +LP LR LD N Sbjct: 652 RSLEQLYLSHNKLETLPTQLGQCFGLRLLDLSHNG------------------------- 686 Query: 406 LRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKL 516 LR LP LGLL SL+ L +SYN++ LPD + KL Sbjct: 687 LRSLPPELGLLQSLQHLALSYNALESLPDELFFCHKL 723 Score = 54.3 bits (129), Expect = 2e-07 Identities = 36/108 (33%), Positives = 60/108 (55%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 + +L ++ L + N+L++LP +G LR+L++S N L+SLP + ++L+ L ++ Sbjct: 648 VRKLRSLEQLYLSHNKLETLPTQLGQCFGLRLLDLSHNGLRSLPPELGLLQSLQHLALSY 707 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLN 327 N L LPD L F H LR L + + LT L + + AL L + N Sbjct: 708 NALESLPDEL-FFCHKLRTLLLGYDHLTQLSPDVAALQALSRLGLKGN 754 Score = 53.1 bits (126), Expect = 5e-07 Identities = 33/84 (39%), Positives = 48/84 (57%), Gaps = 1/84 (1%) Frame = +1 Query: 28 VLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRL-P 204 +LD+ N L+SLP +G L L+ L +S N L+SLP + C L L ++ LT+L P Sbjct: 679 LLDLSHNGLRSLPPELGLLQSLQHLALSYNALESLPDELFFCHKLRTLLLGYDHLTQLSP 738 Query: 205 DTLGFELHSLRRLSVNSNKLTSLP 276 D L +L RL + N+L +LP Sbjct: 739 DVAA--LQALSRLGLKGNRLETLP 760 Score = 52.0 bits (123), Expect = 1e-06 Identities = 45/167 (26%), Positives = 69/167 (41%) Frame = +1 Query: 22 VVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRL 201 +V L + NQ+ +P + L L L +S N L++LP + +C L L+ + N L L Sbjct: 631 LVTLRLWHNQIAYVPEHVRKLRSLEQLYLSHNKLETLPTQLGQCFGLRLLDLSHNGLRSL 690 Query: 202 PDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXX 381 P LG L SL+ L+++ N L SLP LR L Sbjct: 691 PPELGL-LQSLQHLALSYNALESLPDELFFCHKLRTL----------------------- 726 Query: 382 XXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNK 522 + L +L + L +L L + N + LP+ +G L K Sbjct: 727 --LLGYDHLTQLSPDVAALQALSRLGLKGNRLETLPEELGDCKGLKK 771 Score = 44.7 bits (104), Expect = 2e-04 Identities = 54/193 (27%), Positives = 78/193 (40%), Gaps = 5/193 (2%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLK---SLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELN 174 + L + VL +RSN K S+ + G L +L + N LL ++++ L EL Sbjct: 530 LRELKQLKVLSLRSNAGKVPASVTDVAGHLQRLSLHNDGARLLAL--NSLKKLAVLRELE 587 Query: 175 ANFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLP--FSTSHMTALRALDARLNCIRAXXX 348 L R+P + F L +L+ L + N L S+ S H L L N I Sbjct: 588 LVACGLERIPHAI-FSLGALQELDLKDNHLRSIEEILSFQHCRKLVTLRLWHNQIAYVPE 646 Query: 349 XXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFS 528 S N L LP LG LR LD+S+N + LP +G L L + Sbjct: 647 HVRKLRSLEQLYLSHNK--LETLPTQLGQCFGLRLLDLSHNGLRSLPPELGLLQSLQHLA 704 Query: 529 AVGNPLICPPMDI 567 N L P ++ Sbjct: 705 LSYNALESLPDEL 717
>PHLPP_HUMAN (O60346) PH domain leucine-rich repeat-containing protein phosphatase| (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory Length = 1717 Score = 60.8 bits (146), Expect = 3e-09 Identities = 35/103 (33%), Positives = 61/103 (59%), Gaps = 1/103 (0%) Frame = +1 Query: 31 LDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDT 210 L+V N L+S+P ++G + L+ + GN LQSLPA +E + L L +FN+ T +P+ Sbjct: 719 LNVSCNALRSVPAAVGVMHNLQTFLLDGNFLQSLPAELENMKQLSYLGLSFNEFTDIPEV 778 Query: 211 LGFELHSLRRLSVNSNKLTSLPF-STSHMTALRALDARLNCIR 336 L +L ++ +L ++ N + +L + M ++ +D RLN IR Sbjct: 779 LE-KLTAVDKLCMSGNCVETLRLQALRKMPHIKHVDLRLNVIR 820 Score = 57.0 bits (136), Expect = 4e-08 Identities = 36/86 (41%), Positives = 48/86 (55%) Frame = +1 Query: 28 VLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPD 207 VLD+ NQ+ LP + C S LR L N L LP +E ++E L+ NQL LP Sbjct: 921 VLDIGHNQICELPARLFCNSSLRKLLAGHNQLARLPERLER-TSVEVLDVQHNQLLELPP 979 Query: 208 TLGFELHSLRRLSVNSNKLTSLPFST 285 L + SLR L+ ++NKL SLP +T Sbjct: 980 NLLMKADSLRFLNASANKLESLPPAT 1005 Score = 50.8 bits (120), Expect = 3e-06 Identities = 53/188 (28%), Positives = 81/188 (43%), Gaps = 8/188 (4%) Frame = +1 Query: 31 LDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDT 210 +DV N+L+++P + KL VL++ N + LPA + +L +L A NQL RLP+ Sbjct: 899 MDVSRNRLENVPEWVCESRKLEVLDIGHNQICELPARLFCNSSLRKLLAGHNQLARLPER 958 Query: 211 LGFELHSLRRLSVNSNKLTSLP----FSTSHMTALRALDARLNCIRAXXXXXXXXXXXXX 378 L E S+ L V N+L LP + L A +L + Sbjct: 959 L--ERTSVEVLDVQHNQLLELPPNLLMKADSLRFLNASANKLESLPPATLSEETNSILQE 1016 Query: 379 XXXSQNFHFLRELPYGLGLLTS---LRELDISYNSISVLPDS-MGCLAKLNKFSAVGNPL 546 + N + +P LLT L+ L ++YN + P S M L +L + GN L Sbjct: 1017 LYLTNNSLTDKCVP----LLTGHPHLKILHMAYNRLQSFPASKMAKLEELEEIDLSGNKL 1072 Query: 547 ICPPMDIV 570 P I+ Sbjct: 1073 KAIPTTIM 1080 Score = 47.8 bits (112), Expect = 2e-05 Identities = 54/205 (26%), Positives = 85/205 (41%), Gaps = 30/205 (14%) Frame = +1 Query: 19 NVVVLDVRSNQLKSLP-NSIGCLSKLRVLNVSGNLLQSLP-ATIEE-------------- 150 +V VLDV+ NQL LP N + LR LN S N L+SLP AT+ E Sbjct: 963 SVEVLDVQHNQLLELPPNLLMKADSLRFLNASANKLESLPPATLSEETNSILQELYLTNN 1022 Query: 151 -----CRAL-------EELNANFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHM 294 C L + L+ +N+L P + +L L + ++ NKL ++P + + Sbjct: 1023 SLTDKCVPLLTGHPHLKILHMAYNRLQSFPASKMAKLEELEEIDLSGNKLKAIPTTIMNC 1082 Query: 295 TALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNS 474 + + A NCI F + +LP ++ +D+S N Sbjct: 1083 RRMHTVIAHSNCIEV-------------------FPEVMQLP-------EIKCVDLSCNE 1116 Query: 475 IS--VLPDSMGCLAKLNKFSAVGNP 543 +S LP+++ KL + GNP Sbjct: 1117 LSEVTLPENLP--PKLQELDLTGNP 1139 Score = 43.9 bits (102), Expect = 3e-04 Identities = 31/110 (28%), Positives = 52/110 (47%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 + R + L++ +N L P ++ + L LNVS N L+S+PA + L+ + Sbjct: 687 LQRFTKLKSLNLSNNHLGDFPLAVCSIPTLAELNVSCNALRSVPAAVGVMHNLQTFLLDG 746 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCI 333 N L LP L + L L ++ N+ T +P +TA+ L NC+ Sbjct: 747 NFLQSLPAELE-NMKQLSYLGLSFNEFTDIPEVLEKLTAVDKLCMSGNCV 795
>LRCH1_MOUSE (P62046) Leucine-rich repeats and calponin homology| domain-containing protein 1 (Calponin homology domain-containing protein 1) Length = 709 Score = 59.7 bits (143), Expect = 6e-09 Identities = 54/189 (28%), Positives = 89/189 (47%), Gaps = 1/189 (0%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRA-LEELNAN 180 + + +++ +L++ N ++ +P +I L L LN+S N L +LPA + C L+ L A+ Sbjct: 106 LCQFVSLEILNLYHNCIRVIPEAIVNLQMLTHLNLSRNQLSALPACL--CGLPLKVLIAS 163 Query: 181 FNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXX 360 N+L LP+ +G +L L L V+ N++T+LP + +LR L+ R N Sbjct: 164 NNKLGSLPEEIG-QLKQLMELDVSCNEITALPQQIGQLKSLRELNVRRN----------- 211 Query: 361 XXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGN 540 +L+ LP L L L + D S N + V+P + +L N Sbjct: 212 --------------YLKVLPPELVDLP-LVKFDFSCNKVLVIPVCFREMKQLQVLLLENN 256 Query: 541 PLICPPMDI 567 PL PP I Sbjct: 257 PLQSPPAQI 265 Score = 58.9 bits (141), Expect = 1e-08 Identities = 55/184 (29%), Positives = 80/184 (43%), Gaps = 1/184 (0%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQL 192 L + V D+ N+L +P + L +LN+ N ++ +P I + L LN + NQL Sbjct: 86 LSDTVRADLSKNRLVEVPMELCQFVSLEILNLYHNCIRVIPEAIVNLQMLTHLNLSRNQL 145 Query: 193 TRLPDTL-GFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXX 369 + LP L G L+ L ++NKL SLP + L LD N I A Sbjct: 146 SALPACLCGL---PLKVLIASNNKLGSLPEEIGQLKQLMELDVSCNEITA---------- 192 Query: 370 XXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPLI 549 LP +G L SLREL++ N + VLP + L L KF N ++ Sbjct: 193 ---------------LPQQIGQLKSLRELNVRRNYLKVLPPELVDL-PLVKFDFSCNKVL 236 Query: 550 CPPM 561 P+ Sbjct: 237 VIPV 240 Score = 50.1 bits (118), Expect = 5e-06 Identities = 44/174 (25%), Positives = 66/174 (37%), Gaps = 22/174 (12%) Frame = +1 Query: 118 LLQSLPATIEECRALEELNANFNQLTRLPDTL--GFELHSLRRLSVNSNKLTSLPFSTSH 291 L + L +EE LN + +L P T G +L R ++ N+L +P Sbjct: 49 LNRGLERALEEAANSGGLNLSARKLKEFPRTTAPGHDLSDTVRADLSKNRLVEVPMELCQ 108 Query: 292 MTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQN--------------------FHFLR 411 +L L+ NCIR S+N + L Sbjct: 109 FVSLEILNLYHNCIRVIPEAIVNLQMLTHLNLSRNQLSALPACLCGLPLKVLIASNNKLG 168 Query: 412 ELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPLICPPMDIVE 573 LP +G L L ELD+S N I+ LP +G L L + + N L P ++V+ Sbjct: 169 SLPEEIGQLKQLMELDVSCNEITALPQQIGQLKSLRELNVRRNYLKVLPPELVD 222
>LRC8A_RAT (Q4V8I7) Leucine-rich repeat-containing protein 8A| Length = 810 Score = 58.5 bits (140), Expect = 1e-08 Identities = 42/152 (27%), Positives = 70/152 (46%) Frame = +1 Query: 46 NQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDTLGFEL 225 N + +P IG L+ L L ++ N ++ +P + CR L L+ + N LT LP +G L Sbjct: 649 NHIAYIPIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTLLPADIGL-L 707 Query: 226 HSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHF 405 +L+ L+V +N++ +LP LRAL N Sbjct: 708 QNLQNLAVTANRIEALPPELFQCRKLRALHLGNN-------------------------V 742 Query: 406 LRELPYGLGLLTSLRELDISYNSISVLPDSMG 501 L+ LP +G LT+L ++++ N + LP +G Sbjct: 743 LQSLPSRVGELTNLTQIELRGNRLECLPVELG 774 Score = 55.1 bits (131), Expect = 1e-07 Identities = 32/92 (34%), Positives = 48/92 (52%) Frame = +1 Query: 31 LDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDT 210 LD+ N L LP IG L L+ L V+ N +++LP + +CR L L+ N L LP Sbjct: 690 LDLSHNNLTLLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSR 749 Query: 211 LGFELHSLRRLSVNSNKLTSLPFSTSHMTALR 306 +G EL +L ++ + N+L LP L+ Sbjct: 750 VG-ELTNLTQIELRGNRLECLPVELGECPLLK 780 Score = 54.7 bits (130), Expect = 2e-07 Identities = 36/108 (33%), Positives = 55/108 (50%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 I L N+ L + N+++ +P + KLR L++S N L LPA I + L+ L Sbjct: 658 IGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTLLPADIGLLQNLQNLAVTA 717 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLN 327 N++ LP L F+ LR L + +N L SLP +T L ++ R N Sbjct: 718 NRIEALPPEL-FQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGN 764 Score = 48.5 bits (114), Expect = 1e-05 Identities = 47/196 (23%), Positives = 88/196 (44%), Gaps = 5/196 (2%) Frame = +1 Query: 1 GIARLLNVVVLDVRSN--QLKSLPNSIGC-LSKLRVLNVSGNLLQSLPATIEECRALEEL 171 G+ L + VL ++SN +L + +G L KL + N L+ + ++++ L EL Sbjct: 539 GLRELKRLKVLRLKSNLSKLPQVVTDVGVHLQKLSINNEGTKLI--VLNSLKKMVNLTEL 596 Query: 172 NANFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLP--FSTSHMTALRALDARLNCIRAXX 345 L R+P ++ F LH+L+ + + N L ++ S H+ L L N I Sbjct: 597 ELIRCDLERIPHSI-FSLHNLQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYNHIAYIP 655 Query: 346 XXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKF 525 ++N + ++P L LR LD+S+N++++LP +G L L Sbjct: 656 IQIGNLTNLERLYLNRNK--IEKIPTQLFYCRKLRYLDLSHNNLTLLPADIGLLQNLQNL 713 Query: 526 SAVGNPLICPPMDIVE 573 + N + P ++ + Sbjct: 714 AVTANRIEALPPELFQ 729 Score = 47.0 bits (110), Expect = 4e-05 Identities = 33/93 (35%), Positives = 52/93 (55%), Gaps = 2/93 (2%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 I L N+ L V +N++++LP + KLR L++ N+LQSLP+ + E L ++ Sbjct: 704 IGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRG 763 Query: 184 NQLTRLPDTLGFELHSLRR--LSVNSNKLTSLP 276 N+L LP LG E L+R L V + ++LP Sbjct: 764 NRLECLPVELG-ECPLLKRSGLVVEEDLFSTLP 795
>EXS_ARATH (Q9LYN8) Leucine-rich repeat receptor protein kinase EXS precursor| (EC 2.7.11.1) (Extra sporogenous cells protein) (EXCESS MICROSPOROCYTES1 protein) Length = 1192 Score = 58.5 bits (140), Expect = 1e-08 Identities = 48/163 (29%), Positives = 77/163 (47%), Gaps = 4/163 (2%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKS-LPNSIGCLSKLRVLNVSGNLLQ-SLPATIEECRALEELNA 177 + L +V + + +N L +P S+ L+ L +L++SGN L S+P + L+ LN Sbjct: 600 LGECLVLVEISLSNNHLSGEIPASLSRLTNLTILDLSGNALTGSIPKEMGNSLKLQGLNL 659 Query: 178 NFNQLT-RLPDTLGFELHSLRRLSVNSNKLTS-LPFSTSHMTALRALDARLNCIRAXXXX 351 NQL +P++ G L SL +L++ NKL +P S ++ L +D N + Sbjct: 660 ANNQLNGHIPESFGL-LGSLVKLNLTKNKLDGPVPASLGNLKELTHMDLSFNNLSGELSS 718 Query: 352 XXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSIS 480 + F E+P LG LT L LD+S N +S Sbjct: 719 ELSTMEKLVGLYIEQNKFTGEIPSELGNLTQLEYLDVSENLLS 761 Score = 48.5 bits (114), Expect = 1e-05 Identities = 52/187 (27%), Positives = 80/187 (42%), Gaps = 5/187 (2%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKS-LPNSIGCLSKLRVLNVSGNLLQSL-PATIEECRALEELNA 177 I+ L N+ L + NQ +P I L L+ L++SGN L L P + E L L+ Sbjct: 85 ISSLKNLRELCLAGNQFSGKIPPEIWNLKHLQTLDLSGNSLTGLLPRLLSELPQLLYLDL 144 Query: 178 NFNQLT-RLPDTLGFELHSLRRLSVNSNKLTS-LPFSTSHMTALRALDARLNCIRAXXXX 351 + N + LP + L +L L V++N L+ +P ++ L L LN Sbjct: 145 SDNHFSGSLPPSFFISLPALSSLDVSNNSLSGEIPPEIGKLSNLSNLYMGLNSFSGQIPS 204 Query: 352 XXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISV-LPDSMGCLAKLNKFS 528 + + F LP + L L +LD+SYN + +P S G L L+ + Sbjct: 205 EIGNISLLKNFAAPSCFFNGPLPKEISKLKHLAKLDLSYNPLKCSIPKSFGELHNLSILN 264 Query: 529 AVGNPLI 549 V LI Sbjct: 265 LVSAELI 271 Score = 44.3 bits (103), Expect = 2e-04 Identities = 39/110 (35%), Positives = 58/110 (52%), Gaps = 3/110 (2%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLK-SLPNSIGCLSKLRVLN-VSGNLLQSLPATIEECRALEELNA 177 I++L ++ LD+ N LK S+P S G L L +LN VS L+ +P + C++L+ L Sbjct: 230 ISKLKHLAKLDLSYNPLKCSIPKSFGELHNLSILNLVSAELIGLIPPELGNCKSLKSLML 289 Query: 178 NFNQLTRLPDTLGFELHSLRRLSVNSNKLT-SLPFSTSHMTALRALDARL 324 +FN L+ P L L S N+L+ SLP S M + LD+ L Sbjct: 290 SFNSLSG-PLPLELSEIPLLTFSAERNQLSGSLP---SWMGKWKVLDSLL 335 Score = 42.0 bits (97), Expect = 0.001 Identities = 43/162 (26%), Positives = 73/162 (45%), Gaps = 4/162 (2%) Frame = +1 Query: 43 SNQLK-SLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTR-LPDTLG 216 +NQ+ S+P + L + + S N +P ++ + L E A++N+L LP +G Sbjct: 410 NNQINGSIPEDLWKLPLMALDLDSNNFTGEIPKSLWKSTNLMEFTASYNRLEGYLPAEIG 469 Query: 217 FELHSLRRLSVNSNKLTS-LPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQ 393 SL+RL ++ N+LT +P +T+L L+ N Sbjct: 470 -NAASLKRLVLSDNQLTGEIPREIGKLTSLSVLNLNANM--------------------- 507 Query: 394 NFHFLRELPYGLGLLTSLRELDISYNSI-SVLPDSMGCLAKL 516 F ++P LG TSL LD+ N++ +PD + LA+L Sbjct: 508 ---FQGKIPVELGDCTSLTTLDLGSNNLQGQIPDKITALAQL 546
>LRC8D_RAT (Q5U308) Leucine-rich repeat-containing protein 8D| Length = 858 Score = 58.5 bits (140), Expect = 1e-08 Identities = 37/110 (33%), Positives = 62/110 (56%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 I + N+ L +N+L+SLP ++ L KLR L+VS N + ++P I + L+ L+ Sbjct: 702 ITHVKNLESLYFSNNKLESLPVAVFSLQKLRCLDVSYNNISTIPIEIGLLQNLQHLHITG 761 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCI 333 N++ LP L F+ LR L++ N + SLP S ++ L L+ + NC+ Sbjct: 762 NKVDVLPKQL-FKCVKLRTLNLGQNCIASLPEKISQLSQLTQLELKGNCL 810 Score = 57.8 bits (138), Expect = 2e-08 Identities = 46/190 (24%), Positives = 88/190 (46%), Gaps = 2/190 (1%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATI--EECRALEELNA 177 + +++NV L++++ +L+ +P++I LS L+ L++ N ++++ I + + L L Sbjct: 631 LKKMMNVAELELQNCELERIPHAIFSLSNLQELDLKSNSIRTIEEIISFQHLKRLTCLKL 690 Query: 178 NFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXX 357 N++ +P ++ + +L L ++NKL SLP + + LR LD N I Sbjct: 691 WHNKIVAIPPSIT-HVKNLESLYFSNNKLESLPVAVFSLQKLRCLDVSYNNIST------ 743 Query: 358 XXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVG 537 +P +GLL +L+ L I+ N + VLP + KL + Sbjct: 744 -------------------IPIEIGLLQNLQHLHITGNKVDVLPKQLFKCVKLRTLNLGQ 784 Query: 538 NPLICPPMDI 567 N + P I Sbjct: 785 NCIASLPEKI 794 Score = 53.1 bits (126), Expect = 5e-07 Identities = 54/194 (27%), Positives = 87/194 (44%), Gaps = 6/194 (3%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGC----LSKLRVLNVSGNLLQSLPATIEECRALEEL 171 + L ++ +L V+SN L +P++I L+KL + N LL + ++++ + EL Sbjct: 584 LRELRHLKILHVKSN-LTKVPSNITDVAPHLTKLVIHNDGTKLL--VLNSLKKMMNVAEL 640 Query: 172 NANFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLP--FSTSHMTALRALDARLNCIRAXX 345 +L R+P + F L +L+ L + SN + ++ S H+ L L N I A Sbjct: 641 ELQNCELERIPHAI-FSLSNLQELDLKSNSIRTIEEIISFQHLKRLTCLKLWHNKIVAIP 699 Query: 346 XXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKF 525 S N L LP + L LR LD+SYN+IS +P +G L L Sbjct: 700 PSITHVKNLESLYFSNNK--LESLPVAVFSLQKLRCLDVSYNNISTIPIEIGLLQNLQHL 757 Query: 526 SAVGNPLICPPMDI 567 GN + P + Sbjct: 758 HITGNKVDVLPKQL 771 Score = 50.1 bits (118), Expect = 5e-06 Identities = 28/82 (34%), Positives = 44/82 (53%) Frame = +1 Query: 31 LDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDT 210 LDV N + ++P IG L L+ L+++GN + LP + +C L LN N + LP+ Sbjct: 734 LDVSYNNISTIPIEIGLLQNLQHLHITGNKVDVLPKQLFKCVKLRTLNLGQNCIASLPEK 793 Query: 211 LGFELHSLRRLSVNSNKLTSLP 276 + +L L +L + N L LP Sbjct: 794 IS-QLSQLTQLELKGNCLDRLP 814 Score = 42.7 bits (99), Expect = 7e-04 Identities = 26/71 (36%), Positives = 35/71 (49%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 I L N+ L + N++ LP + KLR LN+ N + SLP I + L +L Sbjct: 748 IGLLQNLQHLHITGNKVDVLPKQLFKCVKLRTLNLGQNCIASLPEKISQLSQLTQLELKG 807 Query: 184 NQLTRLPDTLG 216 N L RLP LG Sbjct: 808 NCLDRLPAQLG 818 Score = 40.0 bits (92), Expect = 0.005 Identities = 26/74 (35%), Positives = 37/74 (50%) Frame = +1 Query: 31 LDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDT 210 L++ N + SLP I LS+L L + GN L LPA + +CR L++ +L DT Sbjct: 780 LNLGQNCIASLPEKISQLSQLTQLELKGNCLDRLPAQLGQCRMLKKSGLVVED--QLFDT 837 Query: 211 LGFELHSLRRLSVN 252 L E+ VN Sbjct: 838 LPLEVKEALNQDVN 851
>LRC8D_HUMAN (Q7L1W4) Leucine-rich repeat-containing protein 8D| Length = 858 Score = 58.5 bits (140), Expect = 1e-08 Identities = 37/110 (33%), Positives = 61/110 (55%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 I + N+ L +N+L+SLP ++ L KLR L+VS N + +P I + L+ L+ Sbjct: 702 ITHVKNLESLYFSNNKLESLPVAVFSLQKLRCLDVSYNNISMIPIEIGLLQNLQHLHITG 761 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCI 333 N++ LP L F+ LR L++ N +TSLP ++ L L+ + NC+ Sbjct: 762 NKVDILPKQL-FKCIKLRTLNLGQNCITSLPEKVGQLSQLTQLELKGNCL 810 Score = 55.8 bits (133), Expect = 8e-08 Identities = 44/187 (23%), Positives = 87/187 (46%), Gaps = 2/187 (1%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATI--EECRALEELNA 177 + +++NV L++++ +L+ +P++I LS L+ L++ N ++++ I + + L L Sbjct: 631 LKKMMNVAELELQNCELERIPHAIFSLSNLQELDLKSNNIRTIEEIISFQHLKRLTCLKL 690 Query: 178 NFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXX 357 N++ +P ++ + +L L ++NKL SLP + + LR LD N I Sbjct: 691 WHNKIVTIPPSIT-HVKNLESLYFSNNKLESLPVAVFSLQKLRCLDVSYNNISM------ 743 Query: 358 XXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVG 537 +P +GLL +L+ L I+ N + +LP + KL + Sbjct: 744 -------------------IPIEIGLLQNLQHLHITGNKVDILPKQLFKCIKLRTLNLGQ 784 Query: 538 NPLICPP 558 N + P Sbjct: 785 NCITSLP 791 Score = 53.1 bits (126), Expect = 5e-07 Identities = 30/82 (36%), Positives = 45/82 (54%) Frame = +1 Query: 31 LDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDT 210 LDV N + +P IG L L+ L+++GN + LP + +C L LN N +T LP+ Sbjct: 734 LDVSYNNISMIPIEIGLLQNLQHLHITGNKVDILPKQLFKCIKLRTLNLGQNCITSLPEK 793 Query: 211 LGFELHSLRRLSVNSNKLTSLP 276 +G +L L +L + N L LP Sbjct: 794 VG-QLSQLTQLELKGNCLDRLP 814 Score = 52.0 bits (123), Expect = 1e-06 Identities = 53/194 (27%), Positives = 87/194 (44%), Gaps = 6/194 (3%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGC----LSKLRVLNVSGNLLQSLPATIEECRALEEL 171 + L ++ +L V+SN L +P++I L+KL + N LL + ++++ + EL Sbjct: 584 LRELRHLKILHVKSN-LTKVPSNITDVAPHLTKLVIHNDGTKLL--VLNSLKKMMNVAEL 640 Query: 172 NANFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLP--FSTSHMTALRALDARLNCIRAXX 345 +L R+P + F L +L+ L + SN + ++ S H+ L L N I Sbjct: 641 ELQNCELERIPHAI-FSLSNLQELDLKSNNIRTIEEIISFQHLKRLTCLKLWHNKIVTIP 699 Query: 346 XXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKF 525 S N L LP + L LR LD+SYN+IS++P +G L L Sbjct: 700 PSITHVKNLESLYFSNNK--LESLPVAVFSLQKLRCLDVSYNNISMIPIEIGLLQNLQHL 757 Query: 526 SAVGNPLICPPMDI 567 GN + P + Sbjct: 758 HITGNKVDILPKQL 771 Score = 41.6 bits (96), Expect = 0.002 Identities = 25/81 (30%), Positives = 40/81 (49%) Frame = +1 Query: 10 RLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQ 189 + + + L++ N + SLP +G LS+L L + GN L LPA + +CR L++ Sbjct: 773 KCIKLRTLNLGQNCITSLPEKVGQLSQLTQLELKGNCLDRLPAQLGQCRMLKKSGLVVED 832 Query: 190 LTRLPDTLGFELHSLRRLSVN 252 L DTL E+ +N Sbjct: 833 --HLFDTLPLEVKEALNQDIN 851 Score = 41.6 bits (96), Expect = 0.002 Identities = 25/71 (35%), Positives = 35/71 (49%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 I L N+ L + N++ LP + KLR LN+ N + SLP + + L +L Sbjct: 748 IGLLQNLQHLHITGNKVDILPKQLFKCIKLRTLNLGQNCITSLPEKVGQLSQLTQLELKG 807 Query: 184 NQLTRLPDTLG 216 N L RLP LG Sbjct: 808 NCLDRLPAQLG 818
>PHLPL_HUMAN (Q6ZVD8) PH domain leucine-rich repeat protein phosphatase-like (EC| 3.1.3.16) Length = 1323 Score = 58.2 bits (139), Expect = 2e-08 Identities = 53/181 (29%), Positives = 77/181 (42%), Gaps = 8/181 (4%) Frame = +1 Query: 22 VVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRL 201 + VLDV N L +P I LR L + N +Q+LP +E LE L+ N LTRL Sbjct: 527 IEVLDVSYNLLTEVPLRILSSLSLRKLMLGHNHVQNLPTLVEHI-PLEVLDLQHNALTRL 585 Query: 202 PDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARL--------NCIRAXXXXXX 357 PDTL + +LR L+ ++N L SLP + + +L L CI Sbjct: 586 PDTLFSKALNLRYLNASANSLESLPSACTGEESLSMLQLLYLTNNLLTDQCIPVLVGHLH 645 Query: 358 XXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVG 537 Q F + L L L EL++S N + +P ++ +L+ A Sbjct: 646 LRILHLANNQLQTFPASK-----LNKLEQLEELNLSGNKLKTIPTTIANCKRLHTLVAHS 700 Query: 538 N 540 N Sbjct: 701 N 701 Score = 53.1 bits (126), Expect = 5e-07 Identities = 32/101 (31%), Positives = 59/101 (58%), Gaps = 1/101 (0%) Frame = +1 Query: 16 LNVVVLDVRSNQLKSLPNS-IGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQL 192 L++ +L + +NQL++ P S + L +L LN+SGN L+++P TI C+ L L A+ N + Sbjct: 644 LHLRILHLANNQLQTFPASKLNKLEQLEELNLSGNKLKTIPTTIANCKRLHTLVAHSNNI 703 Query: 193 TRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALD 315 + P+ L +L ++ + ++ N LT + + L+ LD Sbjct: 704 SIFPEIL--QLPQIQFVDLSCNDLTEILIPEALPATLQDLD 742 Score = 45.1 bits (105), Expect = 1e-04 Identities = 29/112 (25%), Positives = 55/112 (49%), Gaps = 1/112 (0%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 + + + L++ N LP+ IG L L+ L + GN L +LP + + L L +F Sbjct: 318 LCEISTLTELNLSCNGFHDLPSQIGNLLNLQTLCLDGNFLTTLPEELGNLQQLSSLGISF 377 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFST-SHMTALRALDARLNCIR 336 N +++P+ +L L R+ + N L L + M ++ +D R+N ++ Sbjct: 378 NNFSQIPEVYE-KLTMLDRVVMAGNCLEVLNLGVLNRMNHIKHVDLRMNHLK 428 Score = 44.3 bits (103), Expect = 2e-04 Identities = 35/114 (30%), Positives = 60/114 (52%), Gaps = 5/114 (4%) Frame = +1 Query: 7 ARLLNVVVLDVRSNQLKSLPNSIG---CLSKLRVLNVSGNLL--QSLPATIEECRALEEL 171 ++ LN+ L+ +N L+SLP++ LS L++L ++ NLL Q +P + L L Sbjct: 591 SKALNLRYLNASANSLESLPSACTGEESLSMLQLLYLTNNLLTDQCIPVLVGHLH-LRIL 649 Query: 172 NANFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCI 333 + NQL P + +L L L+++ NKL ++P + ++ L L A N I Sbjct: 650 HLANNQLQTFPASKLNKLEQLEELNLSGNKLKTIPTTIANCKRLHTLVAHSNNI 703 Score = 41.6 bits (96), Expect = 0.002 Identities = 31/101 (30%), Positives = 48/101 (47%) Frame = +1 Query: 31 LDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDT 210 L++ N+L P + +S L LN+S N LP+ I L+ L + N LT LP+ Sbjct: 304 LNLSHNKLGLFPILLCEISTLTELNLSCNGFHDLPSQIGNLLNLQTLCLDGNFLTTLPEE 363 Query: 211 LGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCI 333 LG L L L ++ N + +P +T L + NC+ Sbjct: 364 LG-NLQQLSSLGISFNNFSQIPEVYEKLTMLDRVVMAGNCL 403 Score = 41.6 bits (96), Expect = 0.002 Identities = 42/157 (26%), Positives = 70/157 (44%), Gaps = 4/157 (2%) Frame = +1 Query: 88 KLRVLNVSGNLLQSLPATIEECRALEELNA--NFNQLTRLP--DTLGFELHSLRRLSVNS 255 ++ +++S L+ +P + + + LN NF QL R DTL ++ L+ L+++ Sbjct: 250 RISTVDLSCYSLEEVPEHLFYSQDITYLNLRHNFMQLERPGGLDTL-YKFSQLKGLNLSH 308 Query: 256 NKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHFLRELPYGLGL 435 NKL P ++ L L+ L+C + +FL LP LG Sbjct: 309 NKLGLFPILLCEISTLTELN--LSCNGFHDLPSQIGNLLNLQTLCLDGNFLTTLPEELGN 366 Query: 436 LTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPL 546 L L L IS+N+ S +P+ L L++ GN L Sbjct: 367 LQQLSSLGISFNNFSQIPEVYEKLTMLDRVVMAGNCL 403
>LRC8A_MOUSE (Q80WG5) Leucine-rich repeat-containing protein 8A| Length = 810 Score = 58.2 bits (139), Expect = 2e-08 Identities = 42/152 (27%), Positives = 70/152 (46%) Frame = +1 Query: 46 NQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDTLGFEL 225 N + +P IG L+ L L ++ N ++ +P + CR L L+ + N LT LP +G L Sbjct: 649 NHIAYIPIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGL-L 707 Query: 226 HSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHF 405 +L+ L+V +N++ +LP LRAL N Sbjct: 708 QNLQNLAVTANRIEALPPELFQCRKLRALHLGNN-------------------------V 742 Query: 406 LRELPYGLGLLTSLRELDISYNSISVLPDSMG 501 L+ LP +G LT+L ++++ N + LP +G Sbjct: 743 LQSLPSRVGELTNLTQIELRGNRLECLPVELG 774 Score = 55.1 bits (131), Expect = 1e-07 Identities = 32/92 (34%), Positives = 48/92 (52%) Frame = +1 Query: 31 LDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDT 210 LD+ N L LP IG L L+ L V+ N +++LP + +CR L L+ N L LP Sbjct: 690 LDLSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSR 749 Query: 211 LGFELHSLRRLSVNSNKLTSLPFSTSHMTALR 306 +G EL +L ++ + N+L LP L+ Sbjct: 750 VG-ELTNLTQIELRGNRLECLPVELGECPLLK 780 Score = 54.7 bits (130), Expect = 2e-07 Identities = 36/108 (33%), Positives = 55/108 (50%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 I L N+ L + N+++ +P + KLR L++S N L LPA I + L+ L Sbjct: 658 IGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAVTA 717 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLN 327 N++ LP L F+ LR L + +N L SLP +T L ++ R N Sbjct: 718 NRIEALPPEL-FQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGN 764 Score = 47.8 bits (112), Expect = 2e-05 Identities = 47/196 (23%), Positives = 87/196 (44%), Gaps = 5/196 (2%) Frame = +1 Query: 1 GIARLLNVVVLDVRSN--QLKSLPNSIGC-LSKLRVLNVSGNLLQSLPATIEECRALEEL 171 G+ L + VL ++SN +L + +G L KL + N L+ + ++++ L EL Sbjct: 539 GLRELKRLKVLRLKSNLSKLPQVVTDVGVHLQKLSINNEGTKLI--VLNSLKKMVNLTEL 596 Query: 172 NANFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLP--FSTSHMTALRALDARLNCIRAXX 345 L R+P ++ F LH+L+ + + N L ++ S H+ L L N I Sbjct: 597 ELIRCDLERIPHSI-FSLHNLQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYNHIAYIP 655 Query: 346 XXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKF 525 ++N + ++P L LR LD+S+N+++ LP +G L L Sbjct: 656 IQIGNLTNLERLYLNRNK--IEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNL 713 Query: 526 SAVGNPLICPPMDIVE 573 + N + P ++ + Sbjct: 714 AVTANRIEALPPELFQ 729 Score = 47.0 bits (110), Expect = 4e-05 Identities = 33/93 (35%), Positives = 52/93 (55%), Gaps = 2/93 (2%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 I L N+ L V +N++++LP + KLR L++ N+LQSLP+ + E L ++ Sbjct: 704 IGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRG 763 Query: 184 NQLTRLPDTLGFELHSLRR--LSVNSNKLTSLP 276 N+L LP LG E L+R L V + ++LP Sbjct: 764 NRLECLPVELG-ECPLLKRSGLVVEEDLFSTLP 795
>LGR4_HUMAN (Q9BXB1) Leucine-rich repeat-containing G-protein coupled receptor| 4 precursor (G-protein coupled receptor 48) Length = 951 Score = 58.2 bits (139), Expect = 2e-08 Identities = 50/166 (30%), Positives = 86/166 (51%), Gaps = 3/166 (1%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPN-SIGCLSKLRVLNVSGNLLQSLPA-TIEECRALEELNA 177 ++ L + VL +++NQLK++P+ +I LS L+ L + N + S+P + E L L Sbjct: 101 LSGLKELKVLTLQNNQLKTVPSEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWL 160 Query: 178 NFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLP-FSTSHMTALRALDARLNCIRAXXXXX 354 + N LT +P L +L+ L++ NK++S+P F+ +++++L L N IR Sbjct: 161 DDNSLTEVPVHPLSNLPTLQALTLALNKISSIPDFAFTNLSSLVVLHLHNNKIRGLSQHC 220 Query: 355 XXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPD 492 +++ L E P + SL+EL NSISV+PD Sbjct: 221 FDGLDNLETL-DLSYNNLGEFPQAIKARPSLKELGFHSNSISVIPD 265 Score = 53.5 bits (127), Expect = 4e-07 Identities = 45/179 (25%), Positives = 77/179 (43%), Gaps = 3/179 (1%) Frame = +1 Query: 31 LDVRSNQLKSL-PNSIGCLSKLRVLNVSGNLLQSLPA-TIEECRALEELNANFNQLTRLP 204 L + N L + P ++ L +L+VL + N L+++P+ I AL+ L + N +T +P Sbjct: 86 LQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKTVPSEAIRGLSALQSLRLDANHITSVP 145 Query: 205 DTLGFELHSLRRLSVNSNKLTSLPFST-SHMTALRALDARLNCIRAXXXXXXXXXXXXXX 381 + L LR L ++ N LT +P S++ L+AL LN I + Sbjct: 146 EDSFEGLVQLRHLWLDDNSLTEVPVHPLSNLPTLQALTLALNKISSIPDFAFTNLSSLVV 205 Query: 382 XXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPLICPP 558 N + L +L LD+SYN++ P ++ L + N + P Sbjct: 206 LHLHNNKIRGLSQHCFDGLDNLETLDLSYNNLGEFPQAIKARPSLKELGFHSNSISVIP 264 Score = 35.4 bits (80), Expect = 0.12 Identities = 30/107 (28%), Positives = 51/107 (47%), Gaps = 25/107 (23%) Frame = +1 Query: 31 LDVRSNQLKSLPNSIGCLSK-LRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPD 207 L + ++ S+PN++ K LR L++S N ++ LP+ C ALEE++ NQ+ ++ + Sbjct: 324 LTLTGTKISSIPNNLCQEQKMLRTLDLSYNNIRDLPS-FNGCHALEEISLQRNQIYQIKE 382 Query: 208 ----------------TLGFELHS--------LRRLSVNSNKLTSLP 276 L E+HS + L V+ N+LTS P Sbjct: 383 GTFQGLISLRILDLSRNLIHEIHSRAFATLGPITNLDVSFNELTSFP 429
>LRC8A_HUMAN (Q8IWT6) Leucine-rich repeat-containing protein 8A| Length = 810 Score = 57.8 bits (138), Expect = 2e-08 Identities = 41/152 (26%), Positives = 70/152 (46%) Frame = +1 Query: 46 NQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDTLGFEL 225 N + +P IG L+ L L ++ N ++ +P + CR L L+ + N LT LP +G L Sbjct: 649 NHIAYIPIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGL-L 707 Query: 226 HSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHF 405 +L+ L++ +N++ +LP LRAL N Sbjct: 708 QNLQNLAITANRIETLPPELFQCRKLRALHLGNN-------------------------V 742 Query: 406 LRELPYGLGLLTSLRELDISYNSISVLPDSMG 501 L+ LP +G LT+L ++++ N + LP +G Sbjct: 743 LQSLPSRVGELTNLTQIELRGNRLECLPVELG 774 Score = 54.7 bits (130), Expect = 2e-07 Identities = 31/92 (33%), Positives = 48/92 (52%) Frame = +1 Query: 31 LDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDT 210 LD+ N L LP IG L L+ L ++ N +++LP + +CR L L+ N L LP Sbjct: 690 LDLSHNNLTFLPADIGLLQNLQNLAITANRIETLPPELFQCRKLRALHLGNNVLQSLPSR 749 Query: 211 LGFELHSLRRLSVNSNKLTSLPFSTSHMTALR 306 +G EL +L ++ + N+L LP L+ Sbjct: 750 VG-ELTNLTQIELRGNRLECLPVELGECPLLK 780 Score = 54.3 bits (129), Expect = 2e-07 Identities = 36/108 (33%), Positives = 55/108 (50%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 I L N+ L + N+++ +P + KLR L++S N L LPA I + L+ L Sbjct: 658 IGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAITA 717 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLN 327 N++ LP L F+ LR L + +N L SLP +T L ++ R N Sbjct: 718 NRIETLPPEL-FQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGN 764 Score = 47.8 bits (112), Expect = 2e-05 Identities = 47/196 (23%), Positives = 87/196 (44%), Gaps = 5/196 (2%) Frame = +1 Query: 1 GIARLLNVVVLDVRSN--QLKSLPNSIGC-LSKLRVLNVSGNLLQSLPATIEECRALEEL 171 G+ L + VL ++SN +L + +G L KL + N L+ + ++++ L EL Sbjct: 539 GLRELKRLKVLRLKSNLSKLPQVVTDVGVHLQKLSINNEGTKLI--VLNSLKKMANLTEL 596 Query: 172 NANFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLP--FSTSHMTALRALDARLNCIRAXX 345 L R+P ++ F LH+L+ + + N L ++ S H+ L L N I Sbjct: 597 ELIRCDLERIPHSI-FSLHNLQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYNHIAYIP 655 Query: 346 XXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKF 525 ++N + ++P L LR LD+S+N+++ LP +G L L Sbjct: 656 IQIGNLTNLERLYLNRNK--IEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNL 713 Query: 526 SAVGNPLICPPMDIVE 573 + N + P ++ + Sbjct: 714 AITANRIETLPPELFQ 729 Score = 46.2 bits (108), Expect = 7e-05 Identities = 32/93 (34%), Positives = 51/93 (54%), Gaps = 2/93 (2%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 I L N+ L + +N++++LP + KLR L++ N+LQSLP+ + E L ++ Sbjct: 704 IGLLQNLQNLAITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRG 763 Query: 184 NQLTRLPDTLGFELHSLRR--LSVNSNKLTSLP 276 N+L LP LG E L+R L V + +LP Sbjct: 764 NRLECLPVELG-ECPLLKRSGLVVEEDLFNTLP 795
>LRC57_XENLA (Q6INV3) Leucine-rich repeat-containing protein 57| Length = 238 Score = 57.8 bits (138), Expect = 2e-08 Identities = 33/112 (29%), Positives = 62/112 (55%), Gaps = 2/112 (1%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 + +L + L + NQ+ LP L L+ LN+SGN L++LPA + + R L+ ++ + Sbjct: 80 LCKLKKLETLHLNGNQISQLPADFVQLLALKTLNLSGNRLKTLPAQLFKLRNLDVVDLSK 139 Query: 184 NQLTRLPDTLGFELHSLR--RLSVNSNKLTSLPFSTSHMTALRALDARLNCI 333 N++ +PD E+ L+ L++N N+++ + + SH L+ L NC+ Sbjct: 140 NRIQAIPD----EVSGLQAIELNLNQNQISQISVNISHCPRLKVLRLEENCL 187 Score = 55.5 bits (132), Expect = 1e-07 Identities = 31/99 (31%), Positives = 59/99 (59%) Frame = +1 Query: 31 LDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDT 210 L + +N++ LP+ + L KL L+++GN + LPA + AL+ LN + N+L LP Sbjct: 66 LSLNNNRISRLPDELCKLKKLETLHLNGNQISQLPADFVQLLALKTLNLSGNRLKTLPAQ 125 Query: 211 LGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLN 327 L F+L +L + ++ N++ ++P ++ L+A++ LN Sbjct: 126 L-FKLRNLDVVDLSKNRIQAIP---DEVSGLQAIELNLN 160 Score = 55.5 bits (132), Expect = 1e-07 Identities = 32/107 (29%), Positives = 63/107 (58%) Frame = +1 Query: 19 NVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTR 198 N+ +D+ SN+++ +P +G S L+ L+++ N + LP + + + LE L+ N NQ+++ Sbjct: 39 NLRTIDLSSNKIEVVPPMMGKFSLLKSLSLNNNRISRLPDELCKLKKLETLHLNGNQISQ 98 Query: 199 LPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRA 339 LP +L +L+ L+++ N+L +LP + L +D N I+A Sbjct: 99 LPADF-VQLLALKTLNLSGNRLKTLPAQLFKLRNLDVVDLSKNRIQA 144 Score = 52.8 bits (125), Expect = 7e-07 Identities = 48/189 (25%), Positives = 83/189 (43%), Gaps = 8/189 (4%) Frame = +1 Query: 28 VLDVRSNQLKSLPNSIGCLS-KLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLP 204 V + L P + LS LR +++S N ++ +P + + L+ L+ N N+++RLP Sbjct: 18 VFQLTDKGLTEFPEDLQRLSGNLRTIDLSSNKIEVVPPMMGKFSLLKSLSLNNNRISRLP 77 Query: 205 DTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXX 384 D L +L L L +N N+++ LP + AL+ L+ N Sbjct: 78 DEL-CKLKKLETLHLNGNQISQLPADFVQLLALKTLNLSGNR------------------ 118 Query: 385 XSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKL------NKFSAVG-NP 543 L+ LP L L +L +D+S N I +PD + L + N+ S + N Sbjct: 119 -------LKTLPAQLFKLRNLDVVDLSKNRIQAIPDEVSGLQAIELNLNQNQISQISVNI 171 Query: 544 LICPPMDIV 570 CP + ++ Sbjct: 172 SHCPRLKVL 180 Score = 31.6 bits (70), Expect = 1.7 Identities = 18/53 (33%), Positives = 27/53 (50%) Frame = +1 Query: 415 LPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPLICPPMDIVE 573 +P +G + L+ L ++ N IS LPD + L KL GN + P D V+ Sbjct: 53 VPPMMGKFSLLKSLSLNNNRISRLPDELCKLKKLETLHLNGNQISQLPADFVQ 105
>PHLPP_RAT (Q9WTR8) PH domain leucine-rich repeat protein phosphatase (EC| 3.1.3.16) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) Length = 1696 Score = 57.8 bits (138), Expect = 2e-08 Identities = 33/103 (32%), Positives = 58/103 (56%), Gaps = 1/103 (0%) Frame = +1 Query: 31 LDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDT 210 L+V N L+ +P ++G + L+ + GN LQSLPA +E L L +FN+ T +P+ Sbjct: 682 LNVSCNALQEVPAAVGAMQNLQTFLLDGNFLQSLPAELENMHQLSYLGLSFNEFTDIPEV 741 Query: 211 LGFELHSLRRLSVNSNKLTSLPF-STSHMTALRALDARLNCIR 336 L +L ++ +L + N + +L + M ++ +D RLN +R Sbjct: 742 LE-KLTAVDKLCMAGNCMETLRLQALRRMPHIKHVDLRLNILR 783 Score = 55.8 bits (133), Expect = 8e-08 Identities = 50/168 (29%), Positives = 73/168 (43%), Gaps = 9/168 (5%) Frame = +1 Query: 28 VLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPD 207 VLD+ NQ+ LP + C S LR L N L LP +E ++E L+ NQ+ LP Sbjct: 884 VLDIGHNQICELPARLFCNSSLRKLLAGHNRLARLPERLER-TSVEVLDVQHNQIIELPP 942 Query: 208 TLGFELHSLRRLSVNSNKLTSLP---FSTSHMTALRALDARLN-----CIRAXXXXXXXX 363 L + SLR L+ ++NKL +LP S + L+ L N C+ Sbjct: 943 NLLMKADSLRFLNASANKLETLPPATLSEETSSILQELYLTNNSLTDKCVPLLTGHPRLK 1002 Query: 364 XXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDS-MGC 504 Q+F + + L L E+DIS N + +P + M C Sbjct: 1003 ILHMAYNRLQSFPASK-----MAKLEELEEIDISGNKLKAIPTTIMNC 1045 Score = 49.3 bits (116), Expect = 8e-06 Identities = 32/110 (29%), Positives = 55/110 (50%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 + R + L++ +N L + P+++ + L LNVS N LQ +PA + + L+ + Sbjct: 650 LQRFTKLKSLNLSNNHLGAFPSAVCSIPTLAELNVSCNALQEVPAAVGAMQNLQTFLLDG 709 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCI 333 N L LP L +H L L ++ N+ T +P +TA+ L NC+ Sbjct: 710 NFLQSLPAELE-NMHQLSYLGLSFNEFTDIPEVLEKLTAVDKLCMAGNCM 758 Score = 48.5 bits (114), Expect = 1e-05 Identities = 52/188 (27%), Positives = 80/188 (42%), Gaps = 8/188 (4%) Frame = +1 Query: 31 LDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDT 210 +DV N L+S+P + KL VL++ N + LPA + +L +L A N+L RLP+ Sbjct: 862 MDVSRNCLESVPEWVCESRKLEVLDIGHNQICELPARLFCNSSLRKLLAGHNRLARLPER 921 Query: 211 LGFELHSLRRLSVNSNKLTSLP----FSTSHMTALRALDARLNCIRAXXXXXXXXXXXXX 378 L E S+ L V N++ LP + L A +L + Sbjct: 922 L--ERTSVEVLDVQHNQIIELPPNLLMKADSLRFLNASANKLETLPPATLSEETSSILQE 979 Query: 379 XXXSQNFHFLRELPYGLGLLTS---LRELDISYNSISVLPDS-MGCLAKLNKFSAVGNPL 546 + N + +P LLT L+ L ++YN + P S M L +L + GN L Sbjct: 980 LYLTNNSLTDKCVP----LLTGHPRLKILHMAYNRLQSFPASKMAKLEELEEIDISGNKL 1035 Query: 547 ICPPMDIV 570 P I+ Sbjct: 1036 KAIPTTIM 1043 Score = 46.6 bits (109), Expect = 5e-05 Identities = 49/203 (24%), Positives = 81/203 (39%), Gaps = 28/203 (13%) Frame = +1 Query: 19 NVVVLDVRSNQLKSLP-NSIGCLSKLRVLNVSGNLLQSLP-ATIEECRA----------- 159 +V VLDV+ NQ+ LP N + LR LN S N L++LP AT+ E + Sbjct: 926 SVEVLDVQHNQIIELPPNLLMKADSLRFLNASANKLETLPPATLSEETSSILQELYLTNN 985 Query: 160 ---------------LEELNANFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHM 294 L+ L+ +N+L P + +L L + ++ NKL ++P + + Sbjct: 986 SLTDKCVPLLTGHPRLKILHMAYNRLQSFPASKMAKLEELEEIDISGNKLKAIPTTIMNC 1045 Query: 295 TALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNS 474 + + A NCI F + +LP ++ +D+S N Sbjct: 1046 RRMHTVIAHSNCIEV-------------------FPEVMQLP-------EVKCVDLSCNE 1079 Query: 475 ISVLPDSMGCLAKLNKFSAVGNP 543 +S + KL + GNP Sbjct: 1080 LSEITLPENLPPKLQELDLTGNP 1102 Score = 43.9 bits (102), Expect = 3e-04 Identities = 31/81 (38%), Positives = 43/81 (53%) Frame = +1 Query: 91 LRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDTLGFELHSLRRLSVNSNKLTS 270 L ++VS N L+S+P + E R LE L+ NQ+ LP L F SLR+L N+L Sbjct: 859 LSYMDVSRNCLESVPEWVCESRKLEVLDIGHNQICELPARL-FCNSSLRKLLAGHNRLAR 917 Query: 271 LPFSTSHMTALRALDARLNCI 333 LP T++ LD + N I Sbjct: 918 LP-ERLERTSVEVLDVQHNQI 937 Score = 38.9 bits (89), Expect = 0.010 Identities = 35/147 (23%), Positives = 60/147 (40%), Gaps = 7/147 (4%) Frame = +1 Query: 121 LQSLPATIEECRALEELNANFNQLTR---LPDTLGF----ELHSLRRLSVNSNKLTSLPF 279 L+ LPA + + L LN N L + LP G L+ L++++N L + P Sbjct: 612 LEHLPANLFYSQDLTHLNLKQNFLRQNPSLPAARGLGELQRFTKLKSLNLSNNHLGAFPS 671 Query: 280 STSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELD 459 + + L L+ N ++ NF L+ LP L + L L Sbjct: 672 AVCSIPTLAELNVSCNALQEVPAAVGAMQNLQTFLLDGNF--LQSLPAELENMHQLSYLG 729 Query: 460 ISYNSISVLPDSMGCLAKLNKFSAVGN 540 +S+N + +P+ + L ++K GN Sbjct: 730 LSFNEFTDIPEVLEKLTAVDKLCMAGN 756
>LRC8E_HUMAN (Q6NSJ5) Leucine-rich repeat-containing protein 8E| Length = 796 Score = 57.4 bits (137), Expect = 3e-08 Identities = 38/103 (36%), Positives = 61/103 (59%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 + +L ++ L + N+L++LP+ +G S LR+L+VS N L SLP + + L+ L ++ Sbjct: 649 VRKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLHSLPPEVGLLQNLQHLALSY 708 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRAL 312 N L LP+ L F LR L + N+L+ L + H+ ALRAL Sbjct: 709 NALEALPEEL-FFCRKLRTLLLGDNQLSQL---SPHVGALRAL 747 Score = 56.2 bits (134), Expect = 6e-08 Identities = 46/167 (27%), Positives = 76/167 (45%), Gaps = 2/167 (1%) Frame = +1 Query: 52 LKSLPNSIGCLSKLRVLNVSGNLLQSLPATI--EECRALEELNANFNQLTRLPDTLGFEL 225 L+ +P+++ L L+ L++ N L+S+ + + CR L L NQ+ +P+ + +L Sbjct: 594 LERIPHAVFSLGALQELDLKDNHLRSIEEILSFQHCRKLVTLRLWHNQIAYVPEHVR-KL 652 Query: 226 HSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHF 405 SL +L ++ NKL +LP + LR LD N Sbjct: 653 RSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNG------------------------- 687 Query: 406 LRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPL 546 L LP +GLL +L+ L +SYN++ LP+ + KL N L Sbjct: 688 LHSLPPEVGLLQNLQHLALSYNALEALPEELFFCRKLRTLLLGDNQL 734 Score = 55.8 bits (133), Expect = 8e-08 Identities = 34/83 (40%), Positives = 48/83 (57%) Frame = +1 Query: 28 VLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPD 207 +LDV N L SLP +G L L+ L +S N L++LP + CR L L NQL++L Sbjct: 680 LLDVSHNGLHSLPPEVGLLQNLQHLALSYNALEALPEELFFCRKLRTLLLGDNQLSQLSP 739 Query: 208 TLGFELHSLRRLSVNSNKLTSLP 276 +G L +L RL + N+L +LP Sbjct: 740 HVG-ALRALSRLELKGNRLEALP 761 Score = 50.1 bits (118), Expect = 5e-06 Identities = 50/191 (26%), Positives = 82/191 (42%), Gaps = 3/191 (1%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLK---SLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELN 174 + L + VL +RSN K S+ + G L +L + N L+ ++++ AL EL Sbjct: 531 LRELKQLKVLSLRSNAGKVPASVTDVAGHLQRLSLHNDGARLVAL--NSLKKLAALRELE 588 Query: 175 ANFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXX 354 L R+P + F L +L+ L + N L S+ S + + RL + Sbjct: 589 LVACGLERIPHAV-FSLGALQELDLKDNHLRSIEEILSFQHCRKLVTLRLWHNQIAYVPE 647 Query: 355 XXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAV 534 +++ L LP LGL + LR LD+S+N + LP +G L L + Sbjct: 648 HVRKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLHSLPPEVGLLQNLQHLALS 707 Query: 535 GNPLICPPMDI 567 N L P ++ Sbjct: 708 YNALEALPEEL 718 Score = 38.5 bits (88), Expect = 0.014 Identities = 24/71 (33%), Positives = 34/71 (47%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 + L N+ L + N L++LP + KLR L + N L L + RAL L Sbjct: 695 VGLLQNLQHLALSYNALEALPEELFFCRKLRTLLLGDNQLSQLSPHVGALRALSRLELKG 754 Query: 184 NQLTRLPDTLG 216 N+L LP+ LG Sbjct: 755 NRLEALPEELG 765 Score = 31.6 bits (70), Expect = 1.7 Identities = 15/41 (36%), Positives = 22/41 (53%) Frame = +1 Query: 46 NQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEE 168 NQL L +G L L L + GN L++LP + C L++ Sbjct: 732 NQLSQLSPHVGALRALSRLELKGNRLEALPEELGNCGGLKK 772
>CYAA_SACKL (P23466) Adenylate cyclase (EC 4.6.1.1) (ATP pyrophosphate-lyase)| (Adenylyl cyclase) Length = 1839 Score = 57.0 bits (136), Expect = 4e-08 Identities = 53/208 (25%), Positives = 96/208 (46%), Gaps = 19/208 (9%) Frame = +1 Query: 1 GIARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNAN 180 G ++L N+ +LD+ SN+ + P I + L +++S N + SLP +I + L ++N Sbjct: 721 GFSKLKNLQLLDISSNKFVNYPEVINSCTNLLQIDLSYNKIHSLPVSINQLVKLAKMNLF 780 Query: 181 FNQLTRLPDTLGFELHSLRRLSVNSNKLTSLP---------FSTSH--------MTALRA 309 N+LT + D ++ +LR L++ N++TS+ F T + +T LR Sbjct: 781 NNRLTSVGDL--SQMKNLRTLNLRCNRVTSIECHAPNLQNLFLTDNRISTFDDDLTRLRT 838 Query: 310 LDARLNCIRAX--XXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISV 483 L+ + N I + ++ F EL L L L +L+++ N+++ Sbjct: 839 LELQQNPITSMVCGGNYMANMTSLSLNKAKLSSFSAEL---LSKLPRLEKLELNENNLTQ 895 Query: 484 LPDSMGCLAKLNKFSAVGNPLICPPMDI 567 LP + L +L S N L P +I Sbjct: 896 LPPEINKLTRLIYLSVARNKLESIPDEI 923 Score = 50.4 bits (119), Expect = 3e-06 Identities = 49/176 (27%), Positives = 78/176 (44%), Gaps = 4/176 (2%) Frame = +1 Query: 31 LDVRSNQLKSLP----NSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTR 198 LDV +N LP S LS LR++N+ + PA + + L L+ N + + Sbjct: 638 LDVSNNANIFLPLDFIESAIKLSSLRMVNIRAS---KFPANVTDAYKLVSLDLERNFIKK 694 Query: 199 LPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXX 378 +PD++ F+L++L +++ N L LP S + L+ LD N Sbjct: 695 VPDSI-FKLNNLTIVNLQCNNLERLPPGFSKLKNLQLLDISSN----------------- 736 Query: 379 XXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPL 546 F+ P + T+L ++D+SYN I LP S+ L KL K + N L Sbjct: 737 -------KFVN-YPEVINSCTNLLQIDLSYNKIHSLPVSINQLVKLAKMNLFNNRL 784 Score = 45.8 bits (107), Expect = 9e-05 Identities = 32/85 (37%), Positives = 46/85 (54%) Frame = +1 Query: 82 LSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDTLGFELHSLRRLSVNSNK 261 L+K ++ + S LL LP LE+L N N LT+LP + +L L LSV NK Sbjct: 864 LNKAKLSSFSAELLSKLPR-------LEKLELNENNLTQLPPEIN-KLTRLIYLSVARNK 915 Query: 262 LTSLPFSTSHMTALRALDARLNCIR 336 L S+P S + +L++LD N +R Sbjct: 916 LESIPDEISDLRSLKSLDLHSNNLR 940 Score = 42.0 bits (97), Expect = 0.001 Identities = 33/107 (30%), Positives = 50/107 (46%), Gaps = 1/107 (0%) Frame = +1 Query: 19 NVVVLDVRSNQLK-SLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLT 195 +++ L V N L S+ + L+ LN+S N + + + L EL + N T Sbjct: 982 SLLFLSVADNNLTDSIWPLVNTFQNLKTLNLSYNNFVEISDL--KLQNLTELYLSGNNFT 1039 Query: 196 RLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIR 336 LP L SL+ L +N NKL SLP S ++ L LD N ++ Sbjct: 1040 SLPGEAVQHLRSLKVLMLNGNKLLSLPAELSQLSRLSVLDVGSNQLK 1086
>LRC8E_RAT (Q3KRC6) Leucine-rich repeat-containing protein 8E| Length = 795 Score = 57.0 bits (136), Expect = 4e-08 Identities = 38/103 (36%), Positives = 60/103 (58%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 + +L ++ L + N+L++LP +G LR+L+VS N L+SLP + ++L+ L ++ Sbjct: 648 VRKLRSLEQLYLSHNKLETLPAQLGQCFGLRLLDVSHNGLRSLPPELGLLQSLQHLALSY 707 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRAL 312 N L LPD L F H LR L + N LT + H+ AL+AL Sbjct: 708 NALESLPDEL-FFCHKLRTLLLGYNHLTQF---SPHVAALQAL 746 Score = 55.5 bits (132), Expect = 1e-07 Identities = 47/167 (28%), Positives = 73/167 (43%) Frame = +1 Query: 22 VVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRL 201 +V+L + NQ+ +P + L L L +S N L++LPA + +C L L+ + N L L Sbjct: 631 LVILRLWHNQIAYVPEHVRKLRSLEQLYLSHNKLETLPAQLGQCFGLRLLDVSHNGLRSL 690 Query: 202 PDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXX 381 P LG L SL+ L+++ N L SLP LR L N Sbjct: 691 PPELGL-LQSLQHLALSYNALESLPDELFFCHKLRTLLLGYN------------------ 731 Query: 382 XXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNK 522 H + P+ + L +L L++ N + LP+ +G L K Sbjct: 732 ------HLTQFSPH-VAALQALSRLELKGNRLEALPEELGDCKGLKK 771 Score = 44.7 bits (104), Expect = 2e-04 Identities = 54/193 (27%), Positives = 78/193 (40%), Gaps = 5/193 (2%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLK---SLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELN 174 + L + VL +RSN K S+ + G L +L + N LL ++++ L EL Sbjct: 530 LRELKQLKVLSLRSNAGKVPASVTDVAGHLQRLSLHNDGARLLAL--NSLKKLAVLRELE 587 Query: 175 ANFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLP--FSTSHMTALRALDARLNCIRAXXX 348 L R+P + F L +L+ L + N L S+ S H L L N I Sbjct: 588 LVACGLERIPHAI-FSLGALQELDLKDNHLRSIEEILSFQHCRKLVILRLWHNQIAYVPE 646 Query: 349 XXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFS 528 S N L LP LG LR LD+S+N + LP +G L L + Sbjct: 647 HVRKLRSLEQLYLSHNK--LETLPAQLGQCFGLRLLDVSHNGLRSLPPELGLLQSLQHLA 704 Query: 529 AVGNPLICPPMDI 567 N L P ++ Sbjct: 705 LSYNALESLPDEL 717
>PHLPL_MOUSE (Q8BXA7) PH domain leucine-rich repeat protein phosphatase-like (EC| 3.1.3.16) Length = 1320 Score = 56.6 bits (135), Expect = 5e-08 Identities = 51/179 (28%), Positives = 76/179 (42%), Gaps = 8/179 (4%) Frame = +1 Query: 28 VLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPD 207 +LD+ N L +P I LR L V N + LPA +E LE L+ N L+RLPD Sbjct: 526 ILDISHNLLTEVPMRILSSLSLRKLMVGHNHIHVLPALVEHI-PLEVLDIQHNTLSRLPD 584 Query: 208 TLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARL--------NCIRAXXXXXXXX 363 TL + +LR L+ ++N L SLP + + +L L CI Sbjct: 585 TLFSKALNLRYLNASANSLESLPSACAGEESLSVLQLLYLTSNLLTDQCIPVLVGHPHLR 644 Query: 364 XXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGN 540 Q F + L L L EL++S N ++ +P ++ +L+ A N Sbjct: 645 VLHLANNQLQTFPASK-----LNKLEQLEELNLSGNKLTAIPTTIANCKRLHTLVAHAN 698 Score = 51.6 bits (122), Expect = 2e-06 Identities = 32/97 (32%), Positives = 55/97 (56%), Gaps = 1/97 (1%) Frame = +1 Query: 28 VLDVRSNQLKSLPNS-IGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLP 204 VL + +NQL++ P S + L +L LN+SGN L ++P TI C+ L L A+ N ++ P Sbjct: 645 VLHLANNQLQTFPASKLNKLEQLEELNLSGNKLTAIPTTIANCKRLHTLVAHANNISIFP 704 Query: 205 DTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALD 315 + L +L ++ + ++ N LT + + L+ LD Sbjct: 705 EIL--QLPQIQFVDLSCNDLTEILIPEALPATLQDLD 739 Score = 48.5 bits (114), Expect = 1e-05 Identities = 30/112 (26%), Positives = 58/112 (51%), Gaps = 1/112 (0%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 + + + L + N LP+ IG L L+ L++ GN L +LP + R L L +F Sbjct: 315 LCEISTLTELSLSCNGFHDLPSQIGKLLNLQTLSLDGNGLTALPDELGNLRQLTSLGISF 374 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTSLPF-STSHMTALRALDARLNCIR 336 N +P+ L +L L ++++ N+L L + + M+ ++ +D R+N ++ Sbjct: 375 NDFRHIPEVLE-KLTMLDKVAMAGNRLEVLNLGALTRMSQVKHVDLRMNHLK 425 Score = 47.0 bits (110), Expect = 4e-05 Identities = 36/114 (31%), Positives = 61/114 (53%), Gaps = 5/114 (4%) Frame = +1 Query: 7 ARLLNVVVLDVRSNQLKSLPNSIG---CLSKLRVLNVSGNLL--QSLPATIEECRALEEL 171 ++ LN+ L+ +N L+SLP++ LS L++L ++ NLL Q +P + L L Sbjct: 588 SKALNLRYLNASANSLESLPSACAGEESLSVLQLLYLTSNLLTDQCIPVLVGHPH-LRVL 646 Query: 172 NANFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCI 333 + NQL P + +L L L+++ NKLT++P + ++ L L A N I Sbjct: 647 HLANNQLQTFPASKLNKLEQLEELNLSGNKLTAIPTTIANCKRLHTLVAHANNI 700 Score = 40.8 bits (94), Expect = 0.003 Identities = 44/176 (25%), Positives = 70/176 (39%), Gaps = 4/176 (2%) Frame = +1 Query: 31 LDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQ-SLPA---TIEECRALEELNANFNQLTR 198 +D+ L+ +P + + LN+ N +Q P T+ + L+ LN + N+L Sbjct: 251 VDLSCYSLEEVPEHLFYSQDITYLNLRHNFMQLERPGGLDTLHKFSQLKGLNLSHNKLGL 310 Query: 199 LPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXX 378 P L E+ +L LS++ N LP + L+ L N + A Sbjct: 311 FPVLL-CEISTLTELSLSCNGFHDLPSQIGKLLNLQTLSLDGNGLTA------------- 356 Query: 379 XXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPL 546 LP LG L L L IS+N +P+ + L L+K + GN L Sbjct: 357 ------------LPDELGNLRQLTSLGISFNDFRHIPEVLEKLTMLDKVAMAGNRL 400 Score = 36.2 bits (82), Expect = 0.068 Identities = 50/226 (22%), Positives = 82/226 (36%), Gaps = 64/226 (28%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEE----- 168 I +LLN+ L + N L +LP+ +G L +L L +S N + +P +E+ L++ Sbjct: 338 IGKLLNLQTLSLDGNGLTALPDELGNLRQLTSLGISFNDFRHIPEVLEKLTMLDKVAMAG 397 Query: 169 -------------------------------------------LNANFNQLTRLP----- 204 ++ NQLT L Sbjct: 398 NRLEVLNLGALTRMSQVKHVDLRMNHLKTVITENMEGNKHITHMDLRDNQLTDLDLSSLC 457 Query: 205 --DTLGFELHSLRRLSVNSNKLTSLPFSTSHMTA---------LRALDARLNCIRAXXXX 351 + L E + LR L+++ L +L S + +TA L +L+ N + Sbjct: 458 SLEQLHCERNQLRELTLSGFSLRTLYASWNRLTAVNVYPVPSLLTSLELSQNLLECVPDW 517 Query: 352 XXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLP 489 S N L E+P + SLR+L + +N I VLP Sbjct: 518 ACEAKKLEILDISHNL--LTEVPMRILSSLSLRKLMVGHNHIHVLP 561 Score = 33.5 bits (75), Expect = 0.44 Identities = 45/177 (25%), Positives = 68/177 (38%), Gaps = 17/177 (9%) Frame = +1 Query: 19 NVVVLDVRSNQLKSLPNSIGCL--------SKLRVLNVSGNLLQSLPATIEECRA----- 159 ++ +D+R NQL L S C ++LR L +SG L++L A+ A Sbjct: 437 HITHMDLRDNQLTDLDLSSLCSLEQLHCERNQLRELTLSGFSLRTLYASWNRLTAVNVYP 496 Query: 160 ----LEELNANFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLN 327 L L + N L +PD E L L ++ N LT +P +LR L N Sbjct: 497 VPSLLTSLELSQNLLECVPDW-ACEAKKLEILDISHNLLTEVPMRILSSLSLRKLMVGHN 555 Query: 328 CIRAXXXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSM 498 I + +P L LDI +N++S LPD++ Sbjct: 556 HIHVLPA------------------LVEHIP--------LEVLDIQHNTLSRLPDTL 586
>PHLPP_MOUSE (Q8CHE4) PH domain leucine-rich repeat-containing protein| phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory Length = 1687 Score = 56.6 bits (135), Expect = 5e-08 Identities = 33/103 (32%), Positives = 58/103 (56%), Gaps = 1/103 (0%) Frame = +1 Query: 31 LDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDT 210 L+V N L+ +P ++G + L+ + GN LQSLPA +E L L +FN+ T +P+ Sbjct: 675 LNVSCNALREVPAAVGDMQNLQTFLLDGNFLQSLPAELESMHQLSYLGLSFNEFTDIPEV 734 Query: 211 LGFELHSLRRLSVNSNKLTSLPF-STSHMTALRALDARLNCIR 336 L +L ++ +L + N + +L + M ++ +D RLN +R Sbjct: 735 LE-KLTAVDKLCMAGNCVETLRLQALRRMPHIKHVDLRLNILR 776 Score = 50.8 bits (120), Expect = 3e-06 Identities = 53/188 (28%), Positives = 81/188 (43%), Gaps = 8/188 (4%) Frame = +1 Query: 31 LDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDT 210 +DV N L+S+P + KL VL++ N + LPA + +L +L A N+L RLP+ Sbjct: 855 MDVSRNCLESVPEWVCESRKLEVLDIGHNQICELPARLFCNSSLRKLLAGHNRLARLPER 914 Query: 211 LGFELHSLRRLSVNSNKLTSLP----FSTSHMTALRALDARLNCIRAXXXXXXXXXXXXX 378 L E S+ L V N++T LP + L A +L + Sbjct: 915 L--ERTSVEVLDVQHNQITELPPNLLMKADSLRFLNASANKLETLPPATLSEETSSILQE 972 Query: 379 XXXSQNFHFLRELPYGLGLLTS---LRELDISYNSISVLPDS-MGCLAKLNKFSAVGNPL 546 + N + +P LLT L+ L ++YN + P S M L +L + GN L Sbjct: 973 LYLTNNCLTDKCVP----LLTGHPRLKILHMAYNRLQSFPASKMAKLEELEEIDISGNKL 1028 Query: 547 ICPPMDIV 570 P I+ Sbjct: 1029 KAIPTTIM 1036 Score = 49.7 bits (117), Expect = 6e-06 Identities = 31/110 (28%), Positives = 56/110 (50%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 + R + L++ +N L + P+++ + L LNVS N L+ +PA + + + L+ + Sbjct: 643 LQRFTKLKSLNLSNNHLGAFPSAVCSIPTLAELNVSCNALREVPAAVGDMQNLQTFLLDG 702 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCI 333 N L LP L +H L L ++ N+ T +P +TA+ L NC+ Sbjct: 703 NFLQSLPAELE-SMHQLSYLGLSFNEFTDIPEVLEKLTAVDKLCMAGNCV 751 Score = 47.4 bits (111), Expect = 3e-05 Identities = 49/203 (24%), Positives = 81/203 (39%), Gaps = 28/203 (13%) Frame = +1 Query: 19 NVVVLDVRSNQLKSLP-NSIGCLSKLRVLNVSGNLLQSLP-ATIEECRA----------- 159 +V VLDV+ NQ+ LP N + LR LN S N L++LP AT+ E + Sbjct: 919 SVEVLDVQHNQITELPPNLLMKADSLRFLNASANKLETLPPATLSEETSSILQELYLTNN 978 Query: 160 ---------------LEELNANFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHM 294 L+ L+ +N+L P + +L L + ++ NKL ++P + + Sbjct: 979 CLTDKCVPLLTGHPRLKILHMAYNRLQSFPASKMAKLEELEEIDISGNKLKAIPTTIMNC 1038 Query: 295 TALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNS 474 + + A NCI F + +LP ++ +D+S N Sbjct: 1039 RRMHTVIAHSNCIEV-------------------FPEVMQLP-------EVKCVDLSCNE 1072 Query: 475 ISVLPDSMGCLAKLNKFSAVGNP 543 +S + KL + GNP Sbjct: 1073 LSEITLPENLPPKLQELDLTGNP 1095 Score = 45.1 bits (105), Expect = 1e-04 Identities = 40/113 (35%), Positives = 57/113 (50%), Gaps = 9/113 (7%) Frame = +1 Query: 22 VVVLDVRSNQLKSLPNSIGCLSKLRV---------LNVSGNLLQSLPATIEECRALEELN 174 +V L+V LK+L S L++L V ++VS N L+S+P + E R LE L+ Sbjct: 820 LVTLNVCGYFLKALYASSNELAQLDVYPVPNYLSYMDVSRNCLESVPEWVCESRKLEVLD 879 Query: 175 ANFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCI 333 NQ+ LP L F SLR+L N+L LP T++ LD + N I Sbjct: 880 IGHNQICELPARL-FCNSSLRKLLAGHNRLARLP-ERLERTSVEVLDVQHNQI 930 Score = 42.4 bits (98), Expect = 0.001 Identities = 39/170 (22%), Positives = 67/170 (39%) Frame = +1 Query: 31 LDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDT 210 +D+ L+ LP ++ L LN+ N L+ P T+ R L EL Sbjct: 598 VDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQTP-TLPAARGLGELQ------------ 644 Query: 211 LGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXS 390 L+ L++++N L + P + + L L+ N +R Sbjct: 645 ---RFTKLKSLNLSNNHLGAFPSAVCSIPTLAELNVSCNALREVPAAVGDMQNLQTFLLD 701 Query: 391 QNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGN 540 NF L+ LP L + L L +S+N + +P+ + L ++K GN Sbjct: 702 GNF--LQSLPAELESMHQLSYLGLSFNEFTDIPEVLEKLTAVDKLCMAGN 749
>CNOT6_RAT (Q6AXU9) CCR4-NOT transcription complex subunit 6 (EC 3.1.-.-)| (Cytoplasmic deadenylase) (Carbon catabolite repressor protein 4 homolog) (CCR4 carbon catabolite repression 4-like) Length = 557 Score = 56.2 bits (134), Expect = 6e-08 Identities = 34/85 (40%), Positives = 49/85 (57%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQL 192 L ++ L + N L +P+ I L L L++S N +QSLPA + +L EL+ N+NQL Sbjct: 50 LTHLTALHLSDNSLSCIPSDIAKLHNLVYLDLSHNQIQSLPAELGNMVSLRELHLNYNQL 109 Query: 193 TRLPDTLGFELHSLRRLSVNSNKLT 267 LP LG +L L+ LS+ N LT Sbjct: 110 RVLPFELG-KLFQLQTLSLKGNPLT 133 Score = 52.4 bits (124), Expect = 9e-07 Identities = 34/102 (33%), Positives = 49/102 (48%) Frame = +1 Query: 241 LSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHFLRELP 420 +S L+S +S +H+TAL D L+CI + ++ LP Sbjct: 36 ISGKVRSLSSSLWSLTHLTALHLSDNSLSCIPSDIAKLHNLVYLDLSHNQ-----IQSLP 90 Query: 421 YGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPL 546 LG + SLREL ++YN + VLP +G L +L S GNPL Sbjct: 91 AELGNMVSLRELHLNYNQLRVLPFELGKLFQLQTLSLKGNPL 132 Score = 46.6 bits (109), Expect = 5e-05 Identities = 30/80 (37%), Positives = 46/80 (57%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 IA+L N+V LD+ NQ++SLP +G + LR L+++ N L+ LP + + L+ L+ Sbjct: 70 IAKLHNLVYLDLSHNQIQSLPAELGNMVSLRELHLNYNQLRVLPFELGKLFQLQTLSLKG 129 Query: 184 NQLTRLPDTLGFELHSLRRL 243 N LT+ L E RRL Sbjct: 130 NPLTQDILNLCLEPDGTRRL 149 Score = 39.7 bits (91), Expect = 0.006 Identities = 33/127 (25%), Positives = 59/127 (46%) Frame = +1 Query: 100 LNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPF 279 L +SG + +SL +++ L L+ + N L+ +P + +LH+L L ++ N++ SLP Sbjct: 34 LEISGKV-RSLSSSLWSLTHLTALHLSDNSLSCIPSDIA-KLHNLVYLDLSHNQIQSLPA 91 Query: 280 STSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELD 459 +M +LR L N++ LR LP+ LG L L+ L Sbjct: 92 ELGNMVSLRELHL-------------------------NYNQLRVLPFELGKLFQLQTLS 126 Query: 460 ISYNSIS 480 + N ++ Sbjct: 127 LKGNPLT 133
>CNOT6_MOUSE (Q8K3P5) CCR4-NOT transcription complex subunit 6 (EC 3.1.-.-)| (Cytoplasmic deadenylase) (Carbon catabolite repressor protein 4 homolog) (CCR4 carbon catabolite repression 4-like) Length = 557 Score = 56.2 bits (134), Expect = 6e-08 Identities = 34/85 (40%), Positives = 49/85 (57%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQL 192 L ++ L + N L +P+ I L L L++S N +QSLPA + +L EL+ N+NQL Sbjct: 50 LTHLTALHLSDNSLSCIPSDIAKLHNLVYLDLSHNQIQSLPAELGNMVSLRELHLNYNQL 109 Query: 193 TRLPDTLGFELHSLRRLSVNSNKLT 267 LP LG +L L+ LS+ N LT Sbjct: 110 RVLPFELG-KLFQLQTLSLKGNPLT 133 Score = 52.4 bits (124), Expect = 9e-07 Identities = 34/102 (33%), Positives = 49/102 (48%) Frame = +1 Query: 241 LSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHFLRELP 420 +S L+S +S +H+TAL D L+CI + ++ LP Sbjct: 36 ISGKVRSLSSSLWSLTHLTALHLSDNSLSCIPSDIAKLHNLVYLDLSHNQ-----IQSLP 90 Query: 421 YGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPL 546 LG + SLREL ++YN + VLP +G L +L S GNPL Sbjct: 91 AELGNMVSLRELHLNYNQLRVLPFELGKLFQLQTLSLKGNPL 132 Score = 46.6 bits (109), Expect = 5e-05 Identities = 30/80 (37%), Positives = 46/80 (57%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 IA+L N+V LD+ NQ++SLP +G + LR L+++ N L+ LP + + L+ L+ Sbjct: 70 IAKLHNLVYLDLSHNQIQSLPAELGNMVSLRELHLNYNQLRVLPFELGKLFQLQTLSLKG 129 Query: 184 NQLTRLPDTLGFELHSLRRL 243 N LT+ L E RRL Sbjct: 130 NPLTQDILNLCLEPDGTRRL 149 Score = 39.7 bits (91), Expect = 0.006 Identities = 33/127 (25%), Positives = 59/127 (46%) Frame = +1 Query: 100 LNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPF 279 L +SG + +SL +++ L L+ + N L+ +P + +LH+L L ++ N++ SLP Sbjct: 34 LEISGKV-RSLSSSLWSLTHLTALHLSDNSLSCIPSDIA-KLHNLVYLDLSHNQIQSLPA 91 Query: 280 STSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELD 459 +M +LR L N++ LR LP+ LG L L+ L Sbjct: 92 ELGNMVSLRELHL-------------------------NYNQLRVLPFELGKLFQLQTLS 126 Query: 460 ISYNSIS 480 + N ++ Sbjct: 127 LKGNPLT 133
>CNOT6_XENLA (Q5BJ41) CCR4-NOT transcription complex subunit 6 (EC 3.1.-.-)| (Cytoplasmic deadenylase) Length = 552 Score = 56.2 bits (134), Expect = 6e-08 Identities = 34/85 (40%), Positives = 49/85 (57%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQL 192 L ++ L + N L +P+ I L L L++S N +QSLPA + +L EL+ N+NQL Sbjct: 50 LTHLTALHLSDNSLSCIPSDIAKLHNLVYLDLSHNQIQSLPAELGNMVSLRELHLNYNQL 109 Query: 193 TRLPDTLGFELHSLRRLSVNSNKLT 267 LP LG +L L+ LS+ N LT Sbjct: 110 RVLPFELG-KLFQLQTLSLKGNPLT 133 Score = 52.4 bits (124), Expect = 9e-07 Identities = 34/102 (33%), Positives = 49/102 (48%) Frame = +1 Query: 241 LSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHFLRELP 420 +S L+S +S +H+TAL D L+CI + ++ LP Sbjct: 36 ISGKVRSLSSSLWSLTHLTALHLSDNSLSCIPSDIAKLHNLVYLDLSHNQ-----IQSLP 90 Query: 421 YGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPL 546 LG + SLREL ++YN + VLP +G L +L S GNPL Sbjct: 91 AELGNMVSLRELHLNYNQLRVLPFELGKLFQLQTLSLKGNPL 132 Score = 46.6 bits (109), Expect = 5e-05 Identities = 30/80 (37%), Positives = 46/80 (57%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 IA+L N+V LD+ NQ++SLP +G + LR L+++ N L+ LP + + L+ L+ Sbjct: 70 IAKLHNLVYLDLSHNQIQSLPAELGNMVSLRELHLNYNQLRVLPFELGKLFQLQTLSLKG 129 Query: 184 NQLTRLPDTLGFELHSLRRL 243 N LT+ L E RRL Sbjct: 130 NPLTQDILNLCLEPDGTRRL 149 Score = 39.7 bits (91), Expect = 0.006 Identities = 33/127 (25%), Positives = 59/127 (46%) Frame = +1 Query: 100 LNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPF 279 L +SG + +SL +++ L L+ + N L+ +P + +LH+L L ++ N++ SLP Sbjct: 34 LEISGKV-RSLSSSLWSLTHLTALHLSDNSLSCIPSDIA-KLHNLVYLDLSHNQIQSLPA 91 Query: 280 STSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELD 459 +M +LR L N++ LR LP+ LG L L+ L Sbjct: 92 ELGNMVSLRELHL-------------------------NYNQLRVLPFELGKLFQLQTLS 126 Query: 460 ISYNSIS 480 + N ++ Sbjct: 127 LKGNPLT 133
>LRC10_HUMAN (Q5BKY1) Leucine-rich repeat-containing protein 10| Length = 277 Score = 55.8 bits (133), Expect = 8e-08 Identities = 51/174 (29%), Positives = 76/174 (43%) Frame = +1 Query: 22 VVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRL 201 +V L + N L SLP +G L L++L + N ++LP + + L L N+L L Sbjct: 54 LVKLYLSDNHLNSLPPELGQLQNLQILALDFNNFKALPQVVCTLKQLCILYLGNNKLCDL 113 Query: 202 PDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXX 381 P L L +LR L + +N LT LP ++ L+ L A N +R Sbjct: 114 PSELSL-LQNLRTLWIEANCLTQLPDVVCELSLLKTLHAGSNALRLLPGQLRRLQELRTI 172 Query: 382 XXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNP 543 S N L + P L + L +D+ +NSI P S+ L+ L NP Sbjct: 173 WLSGN--RLTDFPTVLLHMPFLEVIDVDWNSIRYFP-SLAHLSSLKLVIYDHNP 223 Score = 50.4 bits (119), Expect = 3e-06 Identities = 44/154 (28%), Positives = 66/154 (42%) Frame = +1 Query: 28 VLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPD 207 ++D+ +QL+ P + +L L +S N L SLP + + + L+ L +FN LP Sbjct: 33 MVDLSGSQLRRFPLHVCSFRELVKLYLSDNHLNSLPPELGQLQNLQILALDFNNFKALPQ 92 Query: 208 TLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXX 387 + L L L + +NKL LP S + LR L NC+ Sbjct: 93 VV-CTLKQLCILYLGNNKLCDLPSELSLLQNLRTLWIEANCLTQLPDVVCELSLLKTLHA 151 Query: 388 SQNFHFLRELPYGLGLLTSLRELDISYNSISVLP 489 N LR LP L L LR + +S N ++ P Sbjct: 152 GSN--ALRLLPGQLRRLQELRTIWLSGNRLTDFP 183 Score = 48.9 bits (115), Expect = 1e-05 Identities = 33/103 (32%), Positives = 51/103 (49%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 + +L N+ +L + N K+LP + L +L +L + N L LP+ + + L L Sbjct: 71 LGQLQNLQILALDFNNFKALPQVVCTLKQLCILYLGNNKLCDLPSELSLLQNLRTLWIEA 130 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRAL 312 N LT+LPD + EL L+ L SN L LP + LR + Sbjct: 131 NCLTQLPDVV-CELSLLKTLHAGSNALRLLPGQLRRLQELRTI 172 Score = 39.7 bits (91), Expect = 0.006 Identities = 48/179 (26%), Positives = 73/179 (40%) Frame = +1 Query: 10 RLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQ 189 R N VV D+R L +++++SG+ L+ P + R L +L + N Sbjct: 16 RCQNYVVRDLREMPLD------------KMVDLSGSQLRRFPLHVCSFRELVKLYLSDNH 63 Query: 190 LTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXX 369 L LP LG +L +L+ L+++ N +LP + L L N Sbjct: 64 LNSLPPELG-QLQNLQILALDFNNFKALPQVVCTLKQLCILYLGNNK------------- 109 Query: 370 XXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPL 546 L +LP L LL +LR L I N ++ LPD + L+ L A N L Sbjct: 110 ------------LCDLPSELSLLQNLRTLWIEANCLTQLPDVVCELSLLKTLHAGSNAL 156
>LRC47_HUMAN (Q8N1G4) Leucine-rich repeat-containing protein 47| Length = 583 Score = 55.5 bits (132), Expect = 1e-07 Identities = 56/183 (30%), Positives = 77/183 (42%), Gaps = 11/183 (6%) Frame = +1 Query: 31 LDVRSNQL-KSLPNSIGCLSKLRVLNVSGNLLQSLP-------ATIEECRALEELNANFN 186 L +R N L L +G L LRVL++SGN L++LP A L+ LN + N Sbjct: 80 LVLRRNALGPGLSPELGPLPALRVLDLSGNALEALPPGQGLGPAEPPGLPQLQSLNLSGN 139 Query: 187 QLTRLPDTLGFELHSLRRLSVNSNKLTSLP---FSTSHMTALRALDARLNCIRAXXXXXX 357 +L LP L L+ L++ N L S P F + L L A NC Sbjct: 140 RLRELPADLARCAPRLQSLNLTGNCLDSFPAELFRPGALPLLSELAAADNC--------- 190 Query: 358 XXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVG 537 LREL + L SL+ LD+S N +S +P + KL + + G Sbjct: 191 ----------------LRELSPDIAHLASLKTLDLSNNQLSEIPAELADCPKLKEINFRG 234 Query: 538 NPL 546 N L Sbjct: 235 NKL 237
>LRC8E_XENTR (Q68F79) Leucine-rich repeat-containing protein 8E| Length = 806 Score = 55.1 bits (131), Expect = 1e-07 Identities = 50/183 (27%), Positives = 81/183 (44%), Gaps = 2/183 (1%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATI--EECRALEELNA 177 + RL V L++ +L+ +P+++ L+ L+VL++ N L ++ I + CR L L Sbjct: 588 LKRLALVKELELVRCELERIPHAVFSLTNLQVLDLKENTLHTIEEIISLQHCRKLSVLRL 647 Query: 178 NFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXX 357 NQ+ +P+ + +L L LS+N NK+ +P LR LD N IR Sbjct: 648 WHNQIAYIPEHIR-KLKGLEELSLNRNKILVIPSQLFLCNKLRHLDLSNNEIR------- 699 Query: 358 XXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVG 537 ELP +G+L L+ L +S N + LP+ + KL Sbjct: 700 ------------------ELPPEIGVLQLLQYLGLSGNFLEDLPNELFFCQKLKTLKLGQ 741 Query: 538 NPL 546 N L Sbjct: 742 NRL 744 Score = 43.1 bits (100), Expect = 6e-04 Identities = 30/108 (27%), Positives = 54/108 (50%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 I +L + L + N++ +P+ + +KLR L++S N ++ LP I + L+ L + Sbjct: 659 IRKLKGLEELSLNRNKILVIPSQLFLCNKLRHLDLSNNEIRELPPEIGVLQLLQYLGLSG 718 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLN 327 N L LP+ L F L+ L + N+L +L + L L+ + N Sbjct: 719 NFLEDLPNEL-FFCQKLKTLKLGQNRLGNLSPKVGSLVCLVKLELKGN 765
>LRC47_MOUSE (Q505F5) Leucine-rich repeat-containing protein 47| Length = 581 Score = 54.7 bits (130), Expect = 2e-07 Identities = 54/183 (29%), Positives = 78/183 (42%), Gaps = 11/183 (6%) Frame = +1 Query: 31 LDVRSNQL-KSLPNSIGCLSKLRVLNVSGNLLQSLP-------ATIEECRALEELNANFN 186 L +R N L L +G L LRVL++SGN L++LP A L+ LN + N Sbjct: 82 LVLRRNALGPGLSPELGPLPALRVLDLSGNALETLPPGEGLGPAEPPGLPQLQSLNLSGN 141 Query: 187 QLTRLPDTLGFELHSLRRLSVNSNKLTSLP---FSTSHMTALRALDARLNCIRAXXXXXX 357 +L LP L L+ L++ N+L + P F + L L A NC Sbjct: 142 RLRELPADLARCAPRLQSLNLTGNRLDAFPPELFRPGALPLLSELAAADNC--------- 192 Query: 358 XXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVG 537 LREL + L SL+ LD+S N ++ +P + KL + + G Sbjct: 193 ----------------LRELSPDIAHLASLKTLDLSNNQLTEIPAELADCPKLKEINFRG 236 Query: 538 NPL 546 N L Sbjct: 237 NRL 239
>LRC8C_HUMAN (Q8TDW0) Leucine-rich repeat-containing protein 8C (Protein AD158)| Length = 803 Score = 54.7 bits (130), Expect = 2e-07 Identities = 52/188 (27%), Positives = 84/188 (44%), Gaps = 3/188 (1%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATI--EECRALEELNA 177 + ++ N+ L++ L+ +P+++ L L+ L++ N L+S+ + + R L L Sbjct: 585 LKKMTNLTELELVHCDLERIPHAVFSLLSLQELDLKENNLKSIEEIVSFQHLRKLTVLKL 644 Query: 178 NFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXX 357 N +T +P+ + +L SL RLS + NK+ LP +R LD N IR Sbjct: 645 WHNSITYIPEHIK-KLTSLERLSFSHNKIEVLPSHLFLCNKIRYLDLSYNDIRFIPPEIG 703 Query: 358 XXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVG 537 + N + LP L L+ L I NS+SVL +G L L+ G Sbjct: 704 VLQSLQYFSITCNK--VESLPDELYFCKKLKTLKIGKNSLSVLSPKIGNLLFLSYLDVKG 761 Query: 538 NPL-ICPP 558 N I PP Sbjct: 762 NHFEILPP 769 Score = 49.3 bits (116), Expect = 8e-06 Identities = 44/176 (25%), Positives = 77/176 (43%), Gaps = 2/176 (1%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSLPNSIGC--LSKLRVLNVSGNLLQSLPATIEECRALEELNANFN 186 LL++ LD++ N LKS+ + L KL VL + N + +P I++ +LE L+ + N Sbjct: 611 LLSLQELDLKENNLKSIEEIVSFQHLRKLTVLKLWHNSITYIPEHIKKLTSLERLSFSHN 670 Query: 187 QLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXX 366 ++ LP L F + +R L ++ N + +P + +L+ N + + Sbjct: 671 KIEVLPSHL-FLCNKIRYLDLSYNDIRFIPPEIGVLQSLQYFSITCNKVESLPDELYFCK 729 Query: 367 XXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAV 534 +N L L +G L L LD+ N +LP +G L + V Sbjct: 730 KLKTLKIGKNS--LSVLSPKIGNLLFLSYLDVKGNHFEILPPELGDCRALKRAGLV 783 Score = 47.8 bits (112), Expect = 2e-05 Identities = 45/178 (25%), Positives = 73/178 (41%), Gaps = 1/178 (0%) Frame = +1 Query: 37 VRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDTLG 216 V N LK + N L++L +++ L+ +P + +L+EL+ N L + + + Sbjct: 580 VMLNNLKKMTN----LTELELVHCD---LERIPHAVFSLLSLQELDLKENNLKSIEEIVS 632 Query: 217 FE-LHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQ 393 F+ L L L + N +T +P +T+L L N I Sbjct: 633 FQHLRKLTVLKLWHNSITYIPEHIKKLTSLERLSFSHNKIEV------------------ 674 Query: 394 NFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPLICPPMDI 567 LP L L +R LD+SYN I +P +G L L FS N + P ++ Sbjct: 675 -------LPSHLFLCNKIRYLDLSYNDIRFIPPEIGVLQSLQYFSITCNKVESLPDEL 725
>LRC10_MOUSE (Q8K3W2) Leucine-rich repeat-containing protein 10| (Heart-restricted leucine-rich repeat protein) Length = 274 Score = 54.3 bits (129), Expect = 2e-07 Identities = 47/162 (29%), Positives = 69/162 (42%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 + +V L + N L SLP + L L++L + N ++LP + + L L Sbjct: 48 VCSFTELVKLYLSDNHLHSLPPDLAQLQNLQILALDFNNFKALPRVVCTLKQLCILYLGN 107 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXX 363 N+L LPD L L +LR L + SN LT LP ++ L+ L A N +R Sbjct: 108 NKLCDLPDELSL-LQNLRTLWLESNCLTRLPDVVCELSLLKTLHAGSNALRLLPGQLRRL 166 Query: 364 XXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLP 489 S N L + P L + L +D+ NSI P Sbjct: 167 RELRTIWLSGN--QLADFPSVLLRMPFLEVIDVDRNSIRYFP 206 Score = 50.4 bits (119), Expect = 3e-06 Identities = 44/154 (28%), Positives = 67/154 (43%) Frame = +1 Query: 28 VLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPD 207 ++D+ +QL+ P + ++L L +S N L SLP + + + L+ L +FN LP Sbjct: 33 MVDLSGSQLRRFPLHVCSFTELVKLYLSDNHLHSLPPDLAQLQNLQILALDFNNFKALPR 92 Query: 208 TLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXX 387 + L L L + +NKL LP S + LR L NC+ Sbjct: 93 VV-CTLKQLCILYLGNNKLCDLPDELSLLQNLRTLWLESNCLTRLPDVVCELSLLKTLHA 151 Query: 388 SQNFHFLRELPYGLGLLTSLRELDISYNSISVLP 489 N LR LP L L LR + +S N ++ P Sbjct: 152 GSN--ALRLLPGQLRRLRELRTIWLSGNQLADFP 183 Score = 33.1 bits (74), Expect = 0.58 Identities = 39/151 (25%), Positives = 63/151 (41%) Frame = +1 Query: 94 RVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDTLGFELHSLRRLSVNSNKLTSL 273 R++++SG+ L+ P + L +L + N L LP L +L +L+ L+++ N +L Sbjct: 32 RMVDLSGSQLRRFPLHVCSFTELVKLYLSDNHLHSLPPDLA-QLQNLQILALDFNNFKAL 90 Query: 274 PFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRE 453 P + L L N L +LP L LL +LR Sbjct: 91 PRVVCTLKQLCILYLGNNK-------------------------LCDLPDELSLLQNLRT 125 Query: 454 LDISYNSISVLPDSMGCLAKLNKFSAVGNPL 546 L + N ++ LPD + L+ L A N L Sbjct: 126 LWLESNCLTRLPDVVCELSLLKTLHAGSNAL 156
>LRC39_HUMAN (Q96DD0) Leucine-rich repeat-containing protein 39 (Densin hlg)| Length = 335 Score = 53.9 bits (128), Expect = 3e-07 Identities = 33/111 (29%), Positives = 59/111 (53%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 ++ LL + LD+ N ++P ++ + L L++ N L+ LP TIE + L L Sbjct: 172 LSNLLKLTHLDLSMNDFTTIPLAVLNMPALEWLDMGSNKLEQLPDTIERMQNLHTLWLQR 231 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIR 336 N++T LP T+ + +L L +++NKL +P M LR ++ R N ++ Sbjct: 232 NEITCLPQTIS-NMKNLGTLVLSNNKLQDIPVCMEEMANLRFVNFRDNPLK 281 Score = 45.8 bits (107), Expect = 9e-05 Identities = 36/150 (24%), Positives = 63/150 (42%), Gaps = 47/150 (31%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEEL---- 171 I R N++VLD+ N + +P IG L++L+ L +S N ++++P + C +LE+L Sbjct: 102 IGRFQNLIVLDLSRNTISEIPPGIGLLTRLQELILSYNKIKTVPKELSNCASLEKLELAV 161 Query: 172 -------------------------------------------NANFNQLTRLPDTLGFE 222 + N+L +LPDT+ Sbjct: 162 NRDICDLPQELSNLLKLTHLDLSMNDFTTIPLAVLNMPALEWLDMGSNKLEQLPDTIE-R 220 Query: 223 LHSLRRLSVNSNKLTSLPFSTSHMTALRAL 312 + +L L + N++T LP + S+M L L Sbjct: 221 MQNLHTLWLQRNEITCLPQTISNMKNLGTL 250 Score = 43.9 bits (102), Expect = 3e-04 Identities = 36/155 (23%), Positives = 69/155 (44%) Frame = +1 Query: 25 VVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLP 204 V+L + + K+LP+S+ L++L+ + L +P I + L L+ + N ++ +P Sbjct: 63 VILKIEKEEWKTLPSSLLKLNQLQEWQLHRTGLLKIPEFIGRFQNLIVLDLSRNTISEIP 122 Query: 205 DTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXX 384 +G L L+ L ++ NK+ ++P S+ +L L+ +N Sbjct: 123 PGIGL-LTRLQELILSYNKIKTVPKELSNCASLEKLELAVN------------------- 162 Query: 385 XSQNFHFLRELPYGLGLLTSLRELDISYNSISVLP 489 + +LP L L L LD+S N + +P Sbjct: 163 -----RDICDLPQELSNLLKLTHLDLSMNDFTTIP 192 Score = 42.7 bits (99), Expect = 7e-04 Identities = 21/49 (42%), Positives = 28/49 (57%) Frame = +1 Query: 406 LRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPLIC 552 + E+P G+GLLT L+EL +SYN I +P + A L K N IC Sbjct: 118 ISEIPPGIGLLTRLQELILSYNKIKTVPKELSNCASLEKLELAVNRDIC 166
>LRRK2_MOUSE (Q5S006) Leucine-rich repeat serine/threonine-protein kinase 2 (EC| 2.7.11.1) Length = 2527 Score = 53.9 bits (128), Expect = 3e-07 Identities = 44/183 (24%), Positives = 83/183 (45%), Gaps = 4/183 (2%) Frame = +1 Query: 22 VVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEE----CRALEELNANFNQ 189 ++ LD+ SN+ S P+ + L R+ N+ + P + + C +L++LN ++NQ Sbjct: 1037 LIHLDLHSNKFTSFPSFV--LKMPRITNLDASRNDIGPTVVLDPAMKCPSLKQLNLSYNQ 1094 Query: 190 LTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXX 369 L+ +P+ L + L +L + NK++ + S + L+ L+ N I Sbjct: 1095 LSSIPENLAQVVEKLEQLLLEGNKISGI-CSPLSLKELKILNLSKNHI-PSLPGDFLEAC 1152 Query: 370 XXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPLI 549 S +FL +P L +S+ L +S NS + +P+++ L L N + Sbjct: 1153 SKVESFSARMNFLAAMP---ALPSSITSLKLSQNSFTCIPEAIFSLPHLRSLDMSHNNIE 1209 Query: 550 CPP 558 C P Sbjct: 1210 CLP 1212 Score = 52.8 bits (125), Expect = 7e-07 Identities = 46/171 (26%), Positives = 72/171 (42%), Gaps = 26/171 (15%) Frame = +1 Query: 82 LSKLRVLNVSGNLLQSLPAT-IEECRALEELNANFNQLTRLPDTLGFELHSLRRLSVNSN 258 L +L++LN+S N + SLP +E C +E +A N L +P S+ L ++ N Sbjct: 1128 LKELKILNLSKNHIPSLPGDFLEACSKVESFSARMNFLAAMPALPS----SITSLKLSQN 1183 Query: 259 KLTSLPFSTSHMTALRALDARLNCIRAX-----------XXXXXXXXXXXXXXXSQNFHF 405 T +P + + LR+LD N I S+N H Sbjct: 1184 SFTCIPEAIFSLPHLRSLDMSHNNIECLPGPAHWKSLNLRELIFSKNQISTLDFSENPHV 1243 Query: 406 -------------LRELPYGLGLLTSLRELDISYN-SISVLPDSMGCLAKL 516 L+E+P +G L +L LD+SYN + P+ MG L+K+ Sbjct: 1244 WSRVEKLHLSHNKLKEIPPEIGCLENLTSLDVSYNLELRSFPNEMGKLSKI 1294 Score = 48.1 bits (113), Expect = 2e-05 Identities = 44/167 (26%), Positives = 69/167 (41%), Gaps = 9/167 (5%) Frame = +1 Query: 100 LNVSGNLLQSLPATIEEC------RALEELNANFNQLTRLPDTLGFELHSLRRLSVNSNK 261 L++S N L+ + A ++C L +L + N LT P L L L L ++SNK Sbjct: 987 LDLSANELKDIDALSQKCCLSSHLEHLTKLELHQNSLTSFPQQLCETLKCLIHLDLHSNK 1046 Query: 262 LTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLT 441 TS P M + LDA N I Sbjct: 1047 FTSFPSFVLKMPRITNLDASRNDIGPTVVLDPAMK-----------------------CP 1083 Query: 442 SLRELDISYNSISVLPDSMG-CLAKLNKFSAVGNPL--ICPPMDIVE 573 SL++L++SYN +S +P+++ + KL + GN + IC P+ + E Sbjct: 1084 SLKQLNLSYNQLSSIPENLAQVVEKLEQLLLEGNKISGICSPLSLKE 1130
>CYAA_SCHPO (P14605) Adenylate cyclase (EC 4.6.1.1) (ATP pyrophosphate-lyase)| (Adenylyl cyclase) Length = 1692 Score = 53.1 bits (126), Expect = 5e-07 Identities = 48/177 (27%), Positives = 69/177 (38%), Gaps = 24/177 (13%) Frame = +1 Query: 88 KLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDTL--GFELHSLRRLSVNSNK 261 KL+ L++S NL I R LE LN + N + L + G +SL+ L++ +NK Sbjct: 454 KLKRLDISNNLRSPRGKPITALRQLEVLNMSRNDIYELDPLIFSGLSRNSLKELNIANNK 513 Query: 262 LTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNF-------------- 399 L LP ST ++ L LD N S N Sbjct: 514 LFFLPHSTRYLVNLTYLDLSYNNFVTFPLIITELSQLETLNFSHNLLSQISSKIGSLVKL 573 Query: 400 --------HFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPL 546 LP +GLL +L +D+SYN+I+ + C KLN + N L Sbjct: 574 KHLYLQFNDLSNRLPQEIGLLKNLETIDLSYNAITNIASLSEC-PKLNSINVACNLL 629 Score = 47.0 bits (110), Expect = 4e-05 Identities = 34/108 (31%), Positives = 55/108 (50%), Gaps = 1/108 (0%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQL 192 L+N+ LD+ N + P I LS+L LN S NLL + + I L+ L FN L Sbjct: 524 LVNLTYLDLSYNNFVTFPLIITELSQLETLNFSHNLLSQISSKIGSLVKLKHLYLQFNDL 583 Query: 193 T-RLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCI 333 + RLP +G L +L + ++ N +T++ S S L +++ N + Sbjct: 584 SNRLPQEIGL-LKNLETIDLSYNAITNIA-SLSECPKLNSINVACNLL 629 Score = 42.4 bits (98), Expect = 0.001 Identities = 49/216 (22%), Positives = 78/216 (36%), Gaps = 55/216 (25%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQS--LPA------------- 138 + +L ++V LD+ +N +K P + +S L+V+N+S N+L+ LP Sbjct: 725 LGKLKHLVHLDLHANNIKIFPEEVWQVSSLKVVNLSSNILEKIKLPVATSKKLTRTISQL 784 Query: 139 ----------------------TIEEC------------------RALEELNANFNQLTR 198 T+EE + L+ LN ++N LT Sbjct: 785 KIMRTLSGNPVSSLSSQEFVMPTVEELYLVDNRLGNDCFTALEYFKCLKVLNLSYNYLTE 844 Query: 199 LPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXX 378 +P L+ L V+ N+L +L S++ L L A Sbjct: 845 IPSKFFQNFSDLKHLFVSGNELANLSISSTAQVLLETLYA-------------------- 884 Query: 379 XXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVL 486 N + L P L SLR LDIS N++ L Sbjct: 885 -----NGNRLSSFPKNEALSKSLRFLDISTNNLQNL 915
>GPV_RAT (O08770) Platelet glycoprotein V precursor (GPV) (CD42D antigen)| Length = 567 Score = 52.8 bits (125), Expect = 7e-07 Identities = 48/169 (28%), Positives = 77/169 (45%), Gaps = 4/169 (2%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSL-PNSIGCLSKLRVLNVSGNLLQSL-PATIEECRALEELNA 177 +A L + L + N L+S+ P + L L L +SGNLL+SL PA L L Sbjct: 214 LANLGALTELRLERNHLRSIAPGAFDSLGNLSTLTLSGNLLESLPPALFLHVSWLTRLTL 273 Query: 178 NFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFST-SHMTALRALDARLNCIRAXXXXX 354 N L LP+ L E+ LR L +N L +LP + +++ L+ L N + + Sbjct: 274 FENPLEELPEVLFGEMAGLRELWLNGTHLRTLPAAAFRNLSGLQTLGLTRNPLLSALPPG 333 Query: 355 XXXXXXXXXXXSQNFHFLRELPY-GLGLLTSLRELDISYNSISVLPDSM 498 + + + L ELP L L LR++ + +N + LP ++ Sbjct: 334 MFHGLTELRVLAVHTNALEELPEDALRGLGRLRQVSLRHNRLRALPRTL 382
>CPN2_MOUSE (Q9DBB9) Carboxypeptidase N subunit 2 precursor (Carboxypeptidase N| polypeptide 2) (Carboxypeptidase N 83 kDa chain) (Carboxypeptidase N regulatory subunit) (Carboxypeptidase N large subunit) Length = 547 Score = 52.4 bits (124), Expect = 9e-07 Identities = 48/165 (29%), Positives = 79/165 (47%), Gaps = 3/165 (1%) Frame = +1 Query: 1 GIARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATI-EECRALEELNA 177 G L VV L+ + L+ P++ G L +L+ L ++G+ + +L A I +LE+L Sbjct: 71 GSPNLTKVVFLNTQVRHLE--PDAFGGLPRLQDLEITGSPVSNLSAHIFSNLSSLEKLTL 128 Query: 178 NFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFST-SHMTALRALDARLNCIRAXXXXX 354 +F++L LP+ L + L L + N+L +LP + LR L+ N + Sbjct: 129 DFDRLAGLPEDLFCHMDILESLQLQGNQLRTLPGRLFQSLRDLRTLNLAQNLLTQLPKGA 188 Query: 355 XXXXXXXXXXXSQNFHFLRELPYG-LGLLTSLRELDISYNSISVL 486 N + L LP G LG L+SL+EL + N+I+ L Sbjct: 189 FQSLTGLQMLKLSN-NMLARLPEGALGSLSSLQELFLDGNAITEL 232 Score = 44.3 bits (103), Expect = 2e-04 Identities = 31/90 (34%), Positives = 47/90 (52%), Gaps = 2/90 (2%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSLPN-SIGCLSKLRVLNVSGNLLQSL-PATIEECRALEELNANFN 186 L + +L + +N L LP ++G LS L+ L + GN + L P + +LE L N Sbjct: 192 LTGLQMLKLSNNMLARLPEGALGSLSSLQELFLDGNAITELSPHLFSQLFSLEMLWLQHN 251 Query: 187 QLTRLPDTLGFELHSLRRLSVNSNKLTSLP 276 + LP +L LH+L LS+ N L +LP Sbjct: 252 AICHLPVSLFSSLHNLTFLSLKDNALRTLP 281
>CPN2_HUMAN (P22792) Carboxypeptidase N subunit 2 precursor (Carboxypeptidase N| polypeptide 2) (Carboxypeptidase N 83 kDa chain) (Carboxypeptidase N regulatory subunit) (Carboxypeptidase N large subunit) Length = 545 Score = 52.4 bits (124), Expect = 9e-07 Identities = 53/175 (30%), Positives = 80/175 (45%), Gaps = 7/175 (4%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATI-EECRALEELNANFNQ 189 L VV L+ + Q + P++ G L +L L V+G+ +L I +L +L NFN Sbjct: 75 LTKVVFLNTQLCQFR--PDAFGGLPRLEDLEVTGSSFLNLSTNIFSNLTSLGKLTLNFNM 132 Query: 190 LTRLPDTLGFELHSLRRLSVNSNKLTSLPFST-SHMTALRALDARLNCIRAXXXXXXXXX 366 L LP+ L L +L L + N+L +LP +T L+ L+ N + Sbjct: 133 LEALPEGLFQHLAALESLHLQGNQLQALPRRLFQPLTHLKTLNLAQNLLAQLPEELFHPL 192 Query: 367 XXXXXXXSQNFHFLRELPYGL-GLLTSLRELDISYNSISVLP----DSMGCLAKL 516 N + L LP G+ G L SL+EL + N+IS LP + CL +L Sbjct: 193 TSLQTLKLSN-NALSGLPQGVFGKLGSLQELFLDSNNISELPPQVFSQLFCLERL 246 Score = 31.6 bits (70), Expect = 1.7 Identities = 28/86 (32%), Positives = 44/86 (51%), Gaps = 2/86 (2%) Frame = +1 Query: 7 ARLLNVVVLDVRSNQLKSLPNSI-GCLSKLRVLNVSGNLLQSL-PATIEECRALEELNAN 180 A L N+ L + N + LP I L +L L + N L +L PA + LE L+ + Sbjct: 310 AHLSNLRSLMLSYNAITHLPAGIFRDLEELVKLYLGSNNLTALHPALFQNLSKLELLSLS 369 Query: 181 FNQLTRLPDTLGFELHSLRRLSVNSN 258 NQLT LP+ + ++L L+++ N Sbjct: 370 KNQLTTLPEGIFDTNYNLFNLALHGN 395
>LGR5_HUMAN (O75473) Leucine-rich repeat-containing G-protein coupled receptor| 5 precursor (Orphan G-protein coupled receptor HG38) (G-protein coupled receptor 49) (G-protein coupled receptor 67) Length = 907 Score = 51.6 bits (122), Expect = 2e-06 Identities = 46/175 (26%), Positives = 79/175 (45%), Gaps = 5/175 (2%) Frame = +1 Query: 31 LDVRSNQLKSLPN-SIGCLSKLRVLNVSGNLLQSLPA-TIEECRALEELNANFNQLTRLP 204 L + N L +P + L L+VL + N L+ +P ++ R+L+ L + N ++ +P Sbjct: 95 LRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVP 154 Query: 205 DTLGFELHSLRRLSVNSNKLTSLPFSTSH-MTALRALDARLNCIRAXXXXXXXXXXXXXX 381 + LHSLR L ++ N LT +P ++AL+A+ LN I Sbjct: 155 PSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSLVV 214 Query: 382 XXSQN--FHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGN 540 N H L + + L SL LD++YN++ P ++ L+ L + N Sbjct: 215 LHLHNNRIHSLGKKCFDG--LHSLETLDLNYNNLDEFPTAIRTLSNLKELGFHSN 267 Score = 43.1 bits (100), Expect = 6e-04 Identities = 32/107 (29%), Positives = 59/107 (55%), Gaps = 2/107 (1%) Frame = +1 Query: 19 NVVVLDVRSNQLKSLPNSI-GCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLT 195 N+ L + Q+ SLP ++ L L+VL++S NLL+ LP+ C+ L++++ N++ Sbjct: 329 NLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDLPS-FSVCQKLQKIDLRHNEIY 387 Query: 196 RLPDTLGFELHSLRRLSVNSNKLTSL-PFSTSHMTALRALDARLNCI 333 + +L SLR L++ NK+ + P + S + +L LD N + Sbjct: 388 EIKVDTFQQLLSLRSLNLAWNKIAIIHPNAFSTLPSLIKLDLSSNLL 434 Score = 40.4 bits (93), Expect = 0.004 Identities = 28/95 (29%), Positives = 51/95 (53%), Gaps = 1/95 (1%) Frame = +1 Query: 10 RLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPA-TIEECRALEELNANFN 186 +L N+ VLD+ N L+ LP+ C KL+ +++ N + + T ++ +L LN +N Sbjct: 350 QLPNLQVLDLSYNLLEDLPSFSVC-QKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWN 408 Query: 187 QLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSH 291 ++ + L SL +L ++SN L+S P + H Sbjct: 409 KIAIIHPNAFSTLPSLIKLDLSSNLLSSFPITGLH 443 Score = 36.6 bits (83), Expect = 0.052 Identities = 47/195 (24%), Positives = 74/195 (37%), Gaps = 28/195 (14%) Frame = +1 Query: 46 NQLKSLPN-SIGCLSKLRVLNVSGNLLQSL-PATIEECRALEELNANFNQLTRLPDTLGF 219 N++ +P+ + G LS L VL++ N + SL + +LE L+ N+N L P + Sbjct: 196 NKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTAIR- 254 Query: 220 ELHSLRRLSVNSNKLTSLPFST-------------------------SHMTALRALDARL 324 L +L+ L +SN + S+P H+ LR L L Sbjct: 255 TLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSAFQHLPELRTLT--L 312 Query: 325 NCIRAXXXXXXXXXXXXXXXXSQNFHFLRELPYGL-GLLTSLRELDISYNSISVLPDSMG 501 N + + LP + L +L+ LD+SYN + LP Sbjct: 313 NGASQITEFPDLTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDLPSFSV 372 Query: 502 CLAKLNKFSAVGNPL 546 C KL K N + Sbjct: 373 C-QKLQKIDLRHNEI 386
>RGA3_SOLBU (Q7XA40) Putative disease resistance protein RGA3 (RGA1-blb)| (Blight resistance protein B149) Length = 947 Score = 51.6 bits (122), Expect = 2e-06 Identities = 35/102 (34%), Positives = 61/102 (59%), Gaps = 1/102 (0%) Frame = +1 Query: 10 RLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNA-NFN 186 R +++ VL++ +++ + LP+S+G L LR L++SGN + SLP + + + L+ L+ N Sbjct: 533 RFVSLRVLNLSNSEFEQLPSSVGDLVHLRYLDLSGNKICSLPKRLCKLQNLQTLDLYNCQ 592 Query: 187 QLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRAL 312 L+ LP +L SLR L ++ LTS+P +T L+ L Sbjct: 593 SLSCLPKQTS-KLCSLRNLVLDHCPLTSMPPRIGLLTCLKTL 633 Score = 35.0 bits (79), Expect = 0.15 Identities = 29/108 (26%), Positives = 48/108 (44%) Frame = +1 Query: 133 PATIEECRALEELNANFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRAL 312 P+ + +L LN + ++ +LP ++G +H LR L ++ NK+ SLP + L+ L Sbjct: 528 PSLFKRFVSLRVLNLSNSEFEQLPSSVGDLVH-LRYLDLSGNKICSLPKRLCKLQNLQTL 586 Query: 313 DARLNCIRAXXXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLREL 456 D NC + L +P +GLLT L+ L Sbjct: 587 DL-YNCQSLSCLPKQTSKLCSLRNLVLDHCPLTSMPPRIGLLTCLKTL 633
>RGA1_SOLBU (Q7XA42) Putative disease resistance protein RGA1 (RGA3-blb)| Length = 1025 Score = 51.2 bits (121), Expect = 2e-06 Identities = 35/105 (33%), Positives = 65/105 (61%), Gaps = 2/105 (1%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNL-LQSLPATIEECRALEELNAN 180 + + +++ VL++R++ L LP+SIG L LR L++SGN +++LP + + + L+ L+ + Sbjct: 567 LQKFVSLRVLNLRNSNLNQLPSSIGDLVHLRYLDLSGNFRIRNLPKRLCKLQNLQTLDLH 626 Query: 181 F-NQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRAL 312 + + L+ LP +L SLR L ++ LTS P +T L++L Sbjct: 627 YCDSLSCLPKQTS-KLGSLRNLLLDGCSLTSTPPRIGLLTCLKSL 670 Score = 32.3 bits (72), Expect = 0.98 Identities = 28/86 (32%), Positives = 48/86 (55%), Gaps = 3/86 (3%) Frame = +1 Query: 64 PNSIGCLSKLRVLNVSGNLLQSLPATIEECRALE--ELNANFNQLTRLPDTLGFELHSLR 237 P+ + LRVLN+ + L LP++I + L +L+ NF ++ LP L +L +L+ Sbjct: 564 PSLLQKFVSLRVLNLRNSNLNQLPSSIGDLVHLRYLDLSGNF-RIRNLPKRL-CKLQNLQ 621 Query: 238 RLSVN-SNKLTSLPFSTSHMTALRAL 312 L ++ + L+ LP TS + +LR L Sbjct: 622 TLDLHYCDSLSCLPKQTSKLGSLRNL 647
>LRRK1_HUMAN (Q38SD2) Leucine-rich repeat serine/threonine-protein kinase 1 (EC| 2.7.11.1) Length = 2038 Score = 50.8 bits (120), Expect = 3e-06 Identities = 48/161 (29%), Positives = 70/161 (43%), Gaps = 8/161 (4%) Frame = +1 Query: 100 LNVSGNLLQSLPATIE-ECRALEELNANFNQLTRLPDTLGFE---LHSLRRLSVNSNKLT 267 L++S N L +LP+ I L +LN + N L LP + L + ++SNKL+ Sbjct: 306 LDLSANCLATLPSVIPWGLINLRKLNLSDNHLGELPGVQSSDEIICSRLLEIDISSNKLS 365 Query: 268 SLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQ---NFHFLRELP-YGLGL 435 LP H++ L+ L A NC+ + + + L ELP L Sbjct: 366 HLPPGFLHLSKLQKLTASKNCLEKLFEEENATNWIGLRKLQELDISDNKLTELPALFLHS 425 Query: 436 LTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPLICPP 558 SL L++S N++ V PD C K K S N L C P Sbjct: 426 FKSLNSLNVSRNNLKVFPDPWACPLKCCKASR--NALECLP 464 Score = 38.9 bits (89), Expect = 0.010 Identities = 44/161 (27%), Positives = 65/161 (40%), Gaps = 8/161 (4%) Frame = +1 Query: 31 LDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIE-ECRALEELNANFNQLTRLPD 207 +D N LK +P + L L L + GN L +LP + CR L+ L+ + NQL + D Sbjct: 478 VDFSENALKEVPLGLFQLDALMFLRLQGNQLAALPPQEKWTCRQLKTLDLSRNQLGKNED 537 Query: 208 TLG------FELHSLRRLSVNSNKLTSLP-FSTSHMTALRALDARLNCIRAXXXXXXXXX 366 L F +R + + P F + + L D L+ + Sbjct: 538 GLKTKRIAFFTTRGRQRSGTEAASVLEFPAFLSESLEVLCLNDNHLDTVPPSVCLLKSLS 597 Query: 367 XXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLP 489 N LRELP LG L +L +LD +IS +P Sbjct: 598 ELYLG----NNPGLRELPPELGQLGNLWQLDTEDLTISNVP 634
>LRC8C_RAT (Q498T9) Leucine-rich repeat-containing protein 8C| Length = 803 Score = 50.8 bits (120), Expect = 3e-06 Identities = 49/188 (26%), Positives = 83/188 (44%), Gaps = 3/188 (1%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATI--EECRALEELNA 177 + ++ N+ L++ L+ +P+++ L L+ L++ N L+S+ + + R L L Sbjct: 585 LKKMTNLTELELVHCDLERIPHAVFSLLSLQELDLKENNLKSIEEIVSFQHLRKLTVLKL 644 Query: 178 NFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXX 357 +N + +P+ + +L SL RL + NK+ LP +R LD N IR Sbjct: 645 WYNSIAYIPEHIK-KLTSLERLFFSHNKVEVLPSHLFLCNKIRYLDLSYNDIRFIPPEIG 703 Query: 358 XXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVG 537 + N + LP L L+ L I NS+SVL +G L L+ G Sbjct: 704 VLQSLQYFSITCNK--VESLPDELYFCKKLKTLKIGKNSLSVLSPKIGNLLFLSYLDIKG 761 Query: 538 NPL-ICPP 558 N + PP Sbjct: 762 NHFEVLPP 769 Score = 47.8 bits (112), Expect = 2e-05 Identities = 46/176 (26%), Positives = 76/176 (43%), Gaps = 2/176 (1%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSLPNSIGC--LSKLRVLNVSGNLLQSLPATIEECRALEELNANFN 186 LL++ LD++ N LKS+ + L KL VL + N + +P I++ +LE L + N Sbjct: 611 LLSLQELDLKENNLKSIEEIVSFQHLRKLTVLKLWYNSIAYIPEHIKKLTSLERLFFSHN 670 Query: 187 QLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXX 366 ++ LP L F + +R L ++ N + +P + +L+ N + + Sbjct: 671 KVEVLPSHL-FLCNKIRYLDLSYNDIRFIPPEIGVLQSLQYFSITCNKVESLPDELYFCK 729 Query: 367 XXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAV 534 +N L L +G L L LDI N VLP +G L + V Sbjct: 730 KLKTLKIGKNS--LSVLSPKIGNLLFLSYLDIKGNHFEVLPPELGDCRALKRAGLV 783 Score = 47.0 bits (110), Expect = 4e-05 Identities = 51/191 (26%), Positives = 80/191 (41%), Gaps = 6/191 (3%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSLPNSI----GCLSKLRVLNVSGNLLQSLPATIEECRALEELNAN 180 L ++ +L ++SN K +P ++ L K+ + N L+ + +++ L EL Sbjct: 541 LKSLKILSIKSNVSK-IPQAVVDVSSHLQKMCIHNDGTKLV--MLNNLKKMTNLTELELV 597 Query: 181 FNQLTRLPDTLGFELHSLRRLSVNSNKLTSLP--FSTSHMTALRALDARLNCIRAXXXXX 354 L R+P + F L SL+ L + N L S+ S H+ L L N I Sbjct: 598 HCDLERIPHAV-FSLLSLQELDLKENNLKSIEEIVSFQHLRKLTVLKLWYNSIAYIPEHI 656 Query: 355 XXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAV 534 S N + LP L L +R LD+SYN I +P +G L L FS Sbjct: 657 KKLTSLERLFFSHNK--VEVLPSHLFLCNKIRYLDLSYNDIRFIPPEIGVLQSLQYFSIT 714 Query: 535 GNPLICPPMDI 567 N + P ++ Sbjct: 715 CNKVESLPDEL 725
>LRC8C_MOUSE (Q8R502) Leucine-rich repeat-containing protein 8C (Protein AD158)| Length = 803 Score = 50.8 bits (120), Expect = 3e-06 Identities = 49/188 (26%), Positives = 83/188 (44%), Gaps = 3/188 (1%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATI--EECRALEELNA 177 + ++ N+ L++ L+ +P+++ L L+ L++ N L+S+ + + R L L Sbjct: 585 LKKMTNLTELELVHCDLERIPHAVFSLLSLQELDLKENNLKSIEEIVSFQHLRKLTVLKL 644 Query: 178 NFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXX 357 +N + +P+ + +L SL RL + NK+ LP +R LD N IR Sbjct: 645 WYNSIAYIPEHIK-KLTSLERLFFSHNKVEVLPSHLFLCNKIRYLDLSYNDIRFIPPEIG 703 Query: 358 XXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVG 537 + N + LP L L+ L I NS+SVL +G L L+ G Sbjct: 704 VLQSLQYFSITCNK--VESLPDELYFCKKLKTLKIGKNSLSVLSPKIGNLLFLSYLDIKG 761 Query: 538 NPL-ICPP 558 N + PP Sbjct: 762 NHFEVLPP 769 Score = 47.8 bits (112), Expect = 2e-05 Identities = 46/176 (26%), Positives = 76/176 (43%), Gaps = 2/176 (1%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSLPNSIGC--LSKLRVLNVSGNLLQSLPATIEECRALEELNANFN 186 LL++ LD++ N LKS+ + L KL VL + N + +P I++ +LE L + N Sbjct: 611 LLSLQELDLKENNLKSIEEIVSFQHLRKLTVLKLWYNSIAYIPEHIKKLTSLERLFFSHN 670 Query: 187 QLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXX 366 ++ LP L F + +R L ++ N + +P + +L+ N + + Sbjct: 671 KVEVLPSHL-FLCNKIRYLDLSYNDIRFIPPEIGVLQSLQYFSITCNKVESLPDELYFCK 729 Query: 367 XXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAV 534 +N L L +G L L LDI N VLP +G L + V Sbjct: 730 KLKTLKIGKNS--LSVLSPKIGNLLFLSYLDIKGNHFEVLPPELGDCRALKRAGLV 783 Score = 47.4 bits (111), Expect = 3e-05 Identities = 52/191 (27%), Positives = 80/191 (41%), Gaps = 6/191 (3%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSLPNSI----GCLSKLRVLNVSGNLLQSLPATIEECRALEELNAN 180 L ++ +L ++SN K +P ++ L K+ V N L+ + +++ L EL Sbjct: 541 LKSLKILSIKSNVSK-IPQAVVDVSSHLQKMCVHNDGTKLV--MLNNLKKMTNLTELELV 597 Query: 181 FNQLTRLPDTLGFELHSLRRLSVNSNKLTSLP--FSTSHMTALRALDARLNCIRAXXXXX 354 L R+P + F L SL+ L + N L S+ S H+ L L N I Sbjct: 598 HCDLERIPHAV-FSLLSLQELDLKENNLKSIEEIVSFQHLRKLTVLKLWYNSIAYIPEHI 656 Query: 355 XXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAV 534 S N + LP L L +R LD+SYN I +P +G L L FS Sbjct: 657 KKLTSLERLFFSHNK--VEVLPSHLFLCNKIRYLDLSYNDIRFIPPEIGVLQSLQYFSIT 714 Query: 535 GNPLICPPMDI 567 N + P ++ Sbjct: 715 CNKVESLPDEL 725
>BRI1_LYCES (Q8GUQ5) Brassinosteroid LRR receptor kinase precursor (EC| 2.7.11.1) (tBRI1) (Altered brassinolide sensitivity 1) (Systemin receptor SR160) Length = 1207 Score = 50.8 bits (120), Expect = 3e-06 Identities = 47/164 (28%), Positives = 75/164 (45%), Gaps = 6/164 (3%) Frame = +1 Query: 7 ARLLNVVVLDVRSNQLKSLPNSIGC---LSKLRVLNVSGNLLQS-LPATIEECRALEELN 174 + LL + LD+ SN L + S C ++ L+VL + NL + +P ++ C L L+ Sbjct: 398 SNLLKLETLDMSSNNLTGVIPSGICKDPMNNLKVLYLQNNLFKGPIPDSLSNCSQLVSLD 457 Query: 175 ANFNQLT-RLPDTLGFELHSLRRLSVNSNKLTS-LPFSTSHMTALRALDARLNCIRAXXX 348 +FN LT +P +LG L L+ L + N+L+ +P ++ AL L N + Sbjct: 458 LSFNYLTGSIPSSLG-SLSKLKDLILWLNQLSGEIPQELMYLQALENLILDFNDLTGPIP 516 Query: 349 XXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSIS 480 N E+P LG L++L L + NSIS Sbjct: 517 ASLSNCTKLNWISLSNNQLSGEIPASLGRLSNLAILKLGNNSIS 560 Score = 30.4 bits (67), Expect = 3.7 Identities = 25/97 (25%), Positives = 52/97 (53%), Gaps = 8/97 (8%) Frame = +1 Query: 19 NVVVLDVRSNQLK-SLPNSIGCLSKLRVLNVSGNLLQS-LPATIEECRALEELNANFNQL 192 +++ LD+ N+L+ S+P +G + L +LN+ N L +P + + + L+ ++N+ Sbjct: 664 SMIFLDLSYNKLEGSIPKELGAMYYLSILNLGHNDLSGMIPQQLGGLKNVAILDLSYNRF 723 Query: 193 T-RLPDTLGFELHSLRRLSVNSNKLT-----SLPFST 285 +P++L L L + +++N L+ S PF T Sbjct: 724 NGTIPNSL-TSLTLLGEIDLSNNNLSGMIPESAPFDT 759
>CNOT6_HUMAN (Q9ULM6) CCR4-NOT transcription complex subunit 6 (EC 3.1.-.-)| (Cytoplasmic deadenylase) (Carbon catabolite repressor protein 4 homolog) (CCR4 carbon catabolite repression 4-like) Length = 557 Score = 50.1 bits (118), Expect = 5e-06 Identities = 32/95 (33%), Positives = 52/95 (54%) Frame = +1 Query: 43 SNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDTLGFE 222 S +++SL S+ L+ L L++S N L +P+ I + L L+ + N++ LP LG Sbjct: 37 SGKVRSLSASLWSLTHLTALHLSDNSLSRIPSDIAKLHNLVYLDLSSNKIRSLPAELG-N 95 Query: 223 LHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLN 327 + SLR L +N+N L LPF + L+ L + N Sbjct: 96 MVSLRELHLNNNLLRVLPFELGKLFQLQTLGLKGN 130 Score = 49.3 bits (116), Expect = 8e-06 Identities = 31/80 (38%), Positives = 47/80 (58%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 IA+L N+V LD+ SN+++SLP +G + LR L+++ NLL+ LP + + L+ L Sbjct: 70 IAKLHNLVYLDLSSNKIRSLPAELGNMVSLRELHLNNNLLRVLPFELGKLFQLQTLGLKG 129 Query: 184 NQLTRLPDTLGFELHSLRRL 243 N LT+ L E RRL Sbjct: 130 NPLTQDILNLYQEPDGTRRL 149 Score = 45.8 bits (107), Expect = 9e-05 Identities = 37/127 (29%), Positives = 60/127 (47%) Frame = +1 Query: 100 LNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPF 279 L +SG + +SL A++ L L+ + N L+R+P + +LH+L L ++SNK+ SLP Sbjct: 34 LEISGKV-RSLSASLWSLTHLTALHLSDNSLSRIPSDIA-KLHNLVYLDLSSNKIRSLPA 91 Query: 280 STSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELD 459 +M +LR L N + LR LP+ LG L L+ L Sbjct: 92 ELGNMVSLRELHL-------------------------NNNLLRVLPFELGKLFQLQTLG 126 Query: 460 ISYNSIS 480 + N ++ Sbjct: 127 LKGNPLT 133
>LRRK2_HUMAN (Q5S007) Leucine-rich repeat serine/threonine-protein kinase 2 (EC| 2.7.11.1) (Dardarin) Length = 2527 Score = 49.3 bits (116), Expect = 8e-06 Identities = 40/155 (25%), Positives = 69/155 (44%), Gaps = 2/155 (1%) Frame = +1 Query: 82 LSKLRVLNVSGNLLQSLPAT-IEECRALEELNANFNQLTRLPDTLGFELHSLRRLSVNSN 258 L +L++LN+S N + SL +E C +E +A N L +P F S+ L ++ N Sbjct: 1128 LKELKILNLSKNHISSLSENFLEACPKVESFSARMNFLAAMP----FLPPSMTILKLSQN 1183 Query: 259 KLTSLPFSTSHMTALRALDARLNCIRAXXXXXX-XXXXXXXXXXSQNFHFLRELPYGLGL 435 K + +P + ++ LR+LD N I+ S N + +L L Sbjct: 1184 KFSCIPEAILNLPHLRSLDMSSNDIQYLPGPAHWKSLNLRELLFSHNQISILDLSEKAYL 1243 Query: 436 LTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGN 540 + + +L +S+N + +P +GCL L N Sbjct: 1244 WSRVEKLHLSHNKLKEIPPEIGCLENLTSLDVSYN 1278 Score = 48.1 bits (113), Expect = 2e-05 Identities = 45/181 (24%), Positives = 84/181 (46%), Gaps = 3/181 (1%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQS---LPATIEECRALEELNANF 183 L ++ LD+ SN+ S P+ + +S + L+VS N + L T++ C L++ N ++ Sbjct: 1034 LKSLTHLDLHSNKFTSFPSYLLKMSCIANLDVSRNDIGPSVVLDPTVK-CPTLKQFNLSY 1092 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXX 363 NQL+ +P+ L + L +L + NK++ + S + L+ L+ N I + Sbjct: 1093 NQLSFVPENLTDVVEKLEQLILEGNKISGI-CSPLRLKELKILNLSKNHI-SSLSENFLE 1150 Query: 364 XXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNP 543 S +FL +P+ L S+ L +S N S +P+++ L L N Sbjct: 1151 ACPKVESFSARMNFLAAMPF---LPPSMTILKLSQNKFSCIPEAILNLPHLRSLDMSSND 1207 Query: 544 L 546 + Sbjct: 1208 I 1208
>LRC8B_HUMAN (Q6P9F7) Leucine-rich repeat-containing protein 8B (T-cell activation| leucine repeat-rich protein) Length = 803 Score = 48.9 bits (115), Expect = 1e-05 Identities = 47/190 (24%), Positives = 85/190 (44%), Gaps = 2/190 (1%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATI--EECRALEELNA 177 + +++N+ L++ S L+ +P+SI L+ L L++ N L+++ I + + L L Sbjct: 581 LKKMVNLKSLELISCDLERIPHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKL 640 Query: 178 NFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXX 357 N + +P +G L +L +LS++ N + +LP T L LD N + Sbjct: 641 WHNNIAYIPAQIG-ALSNLEQLSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQ 699 Query: 358 XXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVG 537 + N + LP GL L+ L + NS+ L +G L+ L +G Sbjct: 700 YLSNLQYFAVTNNN--IEMLPDGLFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIG 757 Query: 538 NPLICPPMDI 567 N L P ++ Sbjct: 758 NYLETLPPEL 767 Score = 43.1 bits (100), Expect = 6e-04 Identities = 41/176 (23%), Positives = 74/176 (42%), Gaps = 1/176 (0%) Frame = +1 Query: 16 LNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLT 195 L + LD ++L L N++ + L+ L + L+ +P +I L EL+ N L Sbjct: 563 LQKLSLDNEGSKLVVL-NNLKKMVNLKSLELISCDLERIPHSIFSLNNLHELDLRENNLK 621 Query: 196 RLPDTLGFE-LHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXX 372 + + + F+ L +L L + N + +P ++ L L Sbjct: 622 TVEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQL-------------------- 661 Query: 373 XXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGN 540 S + + + LP L L T L LD+SYN ++ +P+ + L+ L F+ N Sbjct: 662 -----SLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNN 712 Score = 34.7 bits (78), Expect = 0.20 Identities = 23/70 (32%), Positives = 36/70 (51%), Gaps = 2/70 (2%) Frame = +1 Query: 1 GIARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEE--LN 174 G+ + + L + N L +L +G LS L L + GN L++LP +E C++L+ L Sbjct: 720 GLFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLPPELEGCQSLKRNCLI 779 Query: 175 ANFNQLTRLP 204 N L LP Sbjct: 780 VEENLLNTLP 789
>LRC8E_XENLA (Q6NU09) Leucine-rich repeat-containing protein 8E| Length = 806 Score = 48.9 bits (115), Expect = 1e-05 Identities = 47/190 (24%), Positives = 76/190 (40%), Gaps = 2/190 (1%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATI--EECRALEELNA 177 + RL+ V L++ +L+ +P+++ L+ L+VL++ N L ++ I + CR L L Sbjct: 588 LKRLVLVKELELVRCELERIPHAVFSLTNLQVLDLKENTLHTIEEIISLQHCRKLSVLRL 647 Query: 178 NFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXX 357 NQ+ +PD + +L L LS+N NK+ + Sbjct: 648 WHNQIAYIPDHIR-KLKGLEELSLNRNKILVI---------------------------- 678 Query: 358 XXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVG 537 P L L LR LD+S+N I LP +G L L G Sbjct: 679 --------------------PSQLFLCNKLRHLDLSFNEIRELPPEIGVLQLLQYLGLSG 718 Query: 538 NPLICPPMDI 567 N L P ++ Sbjct: 719 NFLEDLPTEL 728
>GPV_MOUSE (O08742) Platelet glycoprotein V precursor (GPV) (CD42D antigen)| Length = 567 Score = 48.9 bits (115), Expect = 1e-05 Identities = 55/204 (26%), Positives = 79/204 (38%), Gaps = 30/204 (14%) Frame = +1 Query: 31 LDVRSNQLKSL-PNSIGCLSKLRVLNVSGNLLQSLP-ATIEECRALEELNANFNQLTRLP 204 L + N L+S+ P + L L L +SGNLL+SLP A ++ L N L LP Sbjct: 223 LRLERNHLRSVAPGAFDRLGNLSSLTLSGNLLESLPPALFLHVSSVSRLTLFENPLEELP 282 Query: 205 DTLGFELHSLRRLSVNSNKLTSLPFST--------------------------SHMTALR 306 D L E+ LR L +N L++LP + + LR Sbjct: 283 DVLFGEMAGLRELWLNGTHLSTLPAAAFRNLSGLQTLGLTRNPRLSALPRGVFQGLRELR 342 Query: 307 ALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHFLRELPYGL-GLLTSLRELDISYNSISV 483 L N + A S + LR LP L L+SL + + +N + Sbjct: 343 VLGLHTNAL-AELRDDALRGLGHLRQVSLRHNRLRALPRTLFRNLSSLESVQLEHNQLET 401 Query: 484 LP-DSMGCLAKLNKFSAVGNPLIC 552 LP D L +L + NP +C Sbjct: 402 LPGDVFAALPQLTQVLLGHNPWLC 425
>LRC8B_MOUSE (Q5DU41) Leucine-rich repeat-containing protein 8B| Length = 791 Score = 48.5 bits (114), Expect = 1e-05 Identities = 47/190 (24%), Positives = 84/190 (44%), Gaps = 2/190 (1%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATI--EECRALEELNA 177 + +++N+ L++ S L+ +P+SI L+ L L++ N L+++ I + +L L Sbjct: 569 LKKMVNLKSLELLSCDLERIPHSIFSLNNLHELDLKENNLKTVEEIISFQHLPSLSCLKL 628 Query: 178 NFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXX 357 N + +P +G L +L +L + N + SLP T L LD N + Sbjct: 629 WHNNIAYIPAQIG-ALSNLEQLFLGHNNIESLPLQLFLCTKLHYLDLSYNHLTFIPEEIQ 687 Query: 358 XXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVG 537 + N + LP GL L+ L + NS++ L +G L+ L G Sbjct: 688 YLTNLQYFAVTNNN--IEMLPDGLFQCKKLQCLLLGRNSLTDLSPLVGELSNLTHLELTG 745 Query: 538 NPLICPPMDI 567 N L P+++ Sbjct: 746 NYLETLPVEL 755 Score = 43.1 bits (100), Expect = 6e-04 Identities = 51/181 (28%), Positives = 79/181 (43%), Gaps = 2/181 (1%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 ++R+ VV + S Q SL N SKL VLN NL + + ++LE L+ + Sbjct: 537 LSRIPQVVTDLLPSLQKLSLDNEG---SKLVVLN---NLKKMV-----NLKSLELLSCD- 584 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTSLP--FSTSHMTALRALDARLNCIRAXXXXXX 357 L R+P ++ F L++L L + N L ++ S H+ +L L N I Sbjct: 585 --LERIPHSI-FSLNNLHELDLKENNLKTVEEIISFQHLPSLSCLKLWHNNIAYIPAQIG 641 Query: 358 XXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVG 537 N + LP L L T L LD+SYN ++ +P+ + L L F+ Sbjct: 642 ALSNLEQLFLGHNN--IESLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLTNLQYFAVTN 699 Query: 538 N 540 N Sbjct: 700 N 700 Score = 33.9 bits (76), Expect = 0.34 Identities = 16/40 (40%), Positives = 25/40 (62%) Frame = +1 Query: 46 NQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALE 165 N L L +G LS L L ++GN L++LP +E C++L+ Sbjct: 723 NSLTDLSPLVGELSNLTHLELTGNYLETLPVELEGCQSLK 762 Score = 30.0 bits (66), Expect = 4.9 Identities = 22/87 (25%), Positives = 41/87 (47%) Frame = +1 Query: 52 LKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDTLGFELHS 231 L LP+++ L+++ VL++ LPA + + L EL+ + L L F + Sbjct: 417 LNGLPDNVFELTEMEVLSLELIPEVKLPAAVAQLVNLRELHVYHSSLVVDHPALAFLEEN 476 Query: 232 LRRLSVNSNKLTSLPFSTSHMTALRAL 312 LR L + ++ +P H+ L+ L Sbjct: 477 LRILRLKFTEMGKIPRWVFHLKNLKEL 503
>RGA4_SOLBU (Q7XA39) Putative disease resistance protein RGA4 (RGA4-blb)| Length = 988 Score = 48.5 bits (114), Expect = 1e-05 Identities = 36/104 (34%), Positives = 59/104 (56%), Gaps = 1/104 (0%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNA-N 180 + + +++ VL++ ++L+ LP+SIG L LR L++S N +SLP + + + L+ L+ N Sbjct: 523 LKKFVSLRVLNLSYSKLEQLPSSIGDLLHLRYLDLSCNNFRSLPERLCKLQNLQTLDVHN 582 Query: 181 FNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRAL 312 L LP +L SLR L V+ LTS P +T L+ L Sbjct: 583 CYSLNCLPKQTS-KLSSLRHLVVDGCPLTSTPPRIGLLTCLKTL 625 Score = 42.0 bits (97), Expect = 0.001 Identities = 30/84 (35%), Positives = 47/84 (55%), Gaps = 1/84 (1%) Frame = +1 Query: 64 PNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDTLGFELHSLRRL 243 P+ + LRVLN+S + L+ LP++I + L L+ + N LP+ L +L +L+ L Sbjct: 520 PSLLKKFVSLRVLNLSYSKLEQLPSSIGDLLHLRYLDLSCNNFRSLPERL-CKLQNLQTL 578 Query: 244 SV-NSNKLTSLPFSTSHMTALRAL 312 V N L LP TS +++LR L Sbjct: 579 DVHNCYSLNCLPKQTSKLSSLRHL 602
>GP1BA_HUMAN (P07359) Platelet glycoprotein Ib alpha chain precursor| (Glycoprotein Ibalpha) (GP-Ib alpha) (GPIbA) (GPIb-alpha) (Antigen CD42b-alpha) (CD42b antigen) [Contains: Glycocalicin] Length = 626 Score = 48.5 bits (114), Expect = 1e-05 Identities = 35/83 (42%), Positives = 44/83 (53%), Gaps = 1/83 (1%) Frame = +1 Query: 31 LDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLP-ATIEECRALEELNANFNQLTRLPD 207 LD+ NQL+SLP L L VL+VS N L SLP + L+EL N+L LP Sbjct: 98 LDLSHNQLQSLPLLGQTLPALTVLDVSFNRLTSLPLGALRGLGELQELYLKGNELKTLPP 157 Query: 208 TLGFELHSLRRLSVNSNKLTSLP 276 L L +LS+ +N LT LP Sbjct: 158 GLLTPTPKLEKLSLANNNLTELP 180 Score = 44.3 bits (103), Expect = 2e-04 Identities = 35/95 (36%), Positives = 52/95 (54%), Gaps = 4/95 (4%) Frame = +1 Query: 22 VVVLDVRSNQLKSLP-NSIGCLSKLRVLNVSGNLLQSL-PATIEECRALEELNANFNQLT 195 + VLDV N+L SLP ++ L +L+ L + GN L++L P + LE+L+ N LT Sbjct: 118 LTVLDVSFNRLTSLPLGALRGLGELQELYLKGNELKTLPPGLLTPTPKLEKLSLANNNLT 177 Query: 196 RLPDTLGFELHSLRRLSVNSNKLTSLP--FSTSHM 294 LP L L +L L + N L ++P F SH+ Sbjct: 178 ELPAGLLNGLENLDTLLLQENSLYTIPKGFFGSHL 212 Score = 41.2 bits (95), Expect = 0.002 Identities = 27/67 (40%), Positives = 37/67 (55%) Frame = +1 Query: 76 GCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDTLGFELHSLRRLSVNS 255 G L L L++S N LQSLP + AL L+ +FN+LT LP L L+ L + Sbjct: 90 GTLPVLGTLDLSHNQLQSLPLLGQTLPALTVLDVSFNRLTSLPLGALRGLGELQELYLKG 149 Query: 256 NKLTSLP 276 N+L +LP Sbjct: 150 NELKTLP 156
>TLR6_HUMAN (Q9Y2C9) Toll-like receptor 6 precursor| Length = 796 Score = 48.5 bits (114), Expect = 1e-05 Identities = 35/107 (32%), Positives = 56/107 (52%), Gaps = 3/107 (2%) Frame = +1 Query: 19 NVVVLDVRSNQLKSLPNSIGCLS-KLRVLNVSGNLLQSLPATIEECRALEELNANFNQLT 195 ++VVL++ SN L + CL +++VL++ N ++S+P + + AL+ELN FN LT Sbjct: 429 SIVVLNLSSNMLTD--SVFRCLPPRIKVLDLHSNKIKSVPKQVVKLEALQELNVAFNSLT 486 Query: 196 RLPDTLGFELHSLRRLSVNSNKLTSLPF--STSHMTALRALDARLNC 330 LP F S+ + NS S F S M +++A D C Sbjct: 487 DLPGCGSFSSLSVLIIDHNSVSHPSADFFQSCQKMRSIKAGDNPFQC 533 Score = 36.2 bits (82), Expect = 0.068 Identities = 53/193 (27%), Positives = 80/193 (41%), Gaps = 13/193 (6%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSLPNSIGCLSK----LRVLNVSGNLLQSLPATIEECRALEE---L 171 L+ + L ++ N LK L +G ++K L +L+VS N L+S E C +E L Sbjct: 376 LVKLETLILQKNGLKDL-FKVGLMTKDMPSLEILDVSWNSLES-GRHKENCTWVESIVVL 433 Query: 172 NANFNQLTR-----LPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIR 336 N + N LT LP + + L ++SNK+ S+P + AL+ L+ Sbjct: 434 NLSSNMLTDSVFRCLPPRI-------KVLDLHSNKIKSVPKQVVKLEALQELNVA----- 481 Query: 337 AXXXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSIS-VLPDSMGCLAK 513 F+ L +LP G G +SL L I +NS+S D K Sbjct: 482 --------------------FNSLTDLP-GCGSFSSLSVLIIDHNSVSHPSADFFQSCQK 520 Query: 514 LNKFSAVGNPLIC 552 + A NP C Sbjct: 521 MRSIKAGDNPFQC 533
>BRI1_LYCPE (Q8L899) Systemin receptor SR160 precursor (EC 2.7.11.1)| (Brassinosteroid LRR receptor kinase) Length = 1207 Score = 48.5 bits (114), Expect = 1e-05 Identities = 46/164 (28%), Positives = 74/164 (45%), Gaps = 6/164 (3%) Frame = +1 Query: 7 ARLLNVVVLDVRSNQLKSLPNSIGC---LSKLRVLNVSGNLLQS-LPATIEECRALEELN 174 + L + LD+ SN L + S C ++ L+VL + NL + +P ++ C L L+ Sbjct: 398 SNLPKLETLDMSSNNLTGIIPSGICKDPMNNLKVLYLQNNLFKGPIPDSLSNCSQLVSLD 457 Query: 175 ANFNQLT-RLPDTLGFELHSLRRLSVNSNKLTS-LPFSTSHMTALRALDARLNCIRAXXX 348 +FN LT +P +LG L L+ L + N+L+ +P ++ AL L N + Sbjct: 458 LSFNYLTGSIPSSLG-SLSKLKDLILWLNQLSGEIPQELMYLQALENLILDFNDLTGPIP 516 Query: 349 XXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSIS 480 N E+P LG L++L L + NSIS Sbjct: 517 ASLSNCTKLNWISLSNNQLSGEIPASLGRLSNLAILKLGNNSIS 560 Score = 30.4 bits (67), Expect = 3.7 Identities = 25/97 (25%), Positives = 52/97 (53%), Gaps = 8/97 (8%) Frame = +1 Query: 19 NVVVLDVRSNQLK-SLPNSIGCLSKLRVLNVSGNLLQS-LPATIEECRALEELNANFNQL 192 +++ LD+ N+L+ S+P +G + L +LN+ N L +P + + + L+ ++N+ Sbjct: 664 SMIFLDLSYNKLEGSIPKELGAMYYLSILNLGHNDLSGMIPQQLGGLKNVAILDLSYNRF 723 Query: 193 T-RLPDTLGFELHSLRRLSVNSNKLT-----SLPFST 285 +P++L L L + +++N L+ S PF T Sbjct: 724 NGTIPNSL-TSLTLLGEIDLSNNNLSGMIPESAPFDT 759
>VASN_XENTR (Q6DF55) Vasorin precursor| Length = 661 Score = 48.1 bits (113), Expect = 2e-05 Identities = 52/174 (29%), Positives = 78/174 (44%), Gaps = 4/174 (2%) Frame = +1 Query: 28 VLDVRSNQLKSLPNSI-GCLSKLRVLNVSGNLLQSLPA-TIEECRALEELNANFNQLTRL 201 +LD+ NQL SLP + L+ L L+++ N L + A T + LE L N N++ + Sbjct: 78 LLDLSHNQLSSLPGGVFRNLANLSNLDLTSNQLTEISADTFQGLSRLERLYLNGNRIRSI 137 Query: 202 PDTLGFELHSLRRLSVNSNKLTSLP-FSTSHMTALRALDARLNCIRAXXXXXXXXXXXXX 378 + SL L +++N+L + P FS H L LD N I Sbjct: 138 HPEAFKGIESLLELKLSNNQLVTPPAFSLPH---LLLLDLSYNAIPVIQQGVFNAGNIES 194 Query: 379 XXXSQNFHFLRELPYGL-GLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVG 537 + L+E+P L L +L ELD+S N + +P + L KLN VG Sbjct: 195 LRLAGLG--LKEVPEELLSGLKNLHELDLSDNQLDKVPPGLHGLTKLNIAGNVG 246
>LRC20_HUMAN (Q8TCA0) Leucine-rich repeat-containing protein 20| Length = 184 Score = 48.1 bits (113), Expect = 2e-05 Identities = 30/106 (28%), Positives = 60/106 (56%), Gaps = 2/106 (1%) Frame = +1 Query: 28 VLDVRSNQLKSLPNS-IGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLP 204 ++ + +N+LKSL + + S+LR L++ GN L LP+ + + L+ ++ + NQ P Sbjct: 54 LITLANNELKSLTSKFMTTFSQLRELHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFP 113 Query: 205 DTLGFELHSLRRLSVNSNKLTSLPF-STSHMTALRALDARLNCIRA 339 + L L +L +++ N++ +P + M ALR+++ R N + A Sbjct: 114 EQL-TALPALETINLEENEIVDVPVEKLAAMPALRSINLRFNPLNA 158
>IPA4_SHIFL (P18009) 65.4 kDa antigen| Length = 574 Score = 47.4 bits (111), Expect = 3e-05 Identities = 52/187 (27%), Positives = 86/187 (45%), Gaps = 10/187 (5%) Frame = +1 Query: 16 LNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQ-L 192 L++ L++ +N+L SLP + L++L V + N+L +LP+ L +LN +FN+ L Sbjct: 82 LHIRELNISNNELISLPENSPLLTELHVNGNNLNILPTLPS------QLIKLNISFNRNL 135 Query: 193 TRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCI-----RAXXXXXX 357 + LP + L+ LS N L +LP S +T LR RL + R Sbjct: 136 SCLPSLPPY----LQSLSARFNSLETLPELPSTLTILRIEGNRLTVLPELPHRLQELFVS 191 Query: 358 XXXXXXXXXXSQNFHFLRELPYGLGLLTSLRE----LDISYNSISVLPDSMGCLAKLNKF 525 Q+ +L+ L L+ L + LD+S N ++ LP+++ L Sbjct: 192 GNRLQELPEFPQSLKYLKVGENQLRRLSRLPQELLALDVSNNLLTSLPENIITLPICTNV 251 Query: 526 SAVGNPL 546 + GNPL Sbjct: 252 NISGNPL 258
>BRI1_ARATH (O22476) BRASSINOSTEROID INSENSITIVE 1 precursor (EC 2.7.11.1)| (AtBRI1) (Brassinosteroid LRR receptor kinase) Length = 1196 Score = 47.4 bits (111), Expect = 3e-05 Identities = 57/196 (29%), Positives = 82/196 (41%), Gaps = 13/196 (6%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQ-SLPATIEECRALEELNAN 180 ++R +N+ LDV SN + +G S L+ L++SGN L I C L+ LN + Sbjct: 218 VSRCVNLEFLDVSSNNFSTGIPFLGDCSALQHLDISGNKLSGDFSRAISTCTELKLLNIS 277 Query: 181 FNQLTRLPDTLGFELHSLRRLSVNSNKLT-SLP-FSTSHMTALRALDARLNCIRAXXXXX 354 NQ L L SL+ LS+ NK T +P F + L LD N Sbjct: 278 SNQFVGPIPPL--PLKSLQYLSLAENKFTGEIPDFLSGACDTLTGLDLSGNHFYGAVPPF 335 Query: 355 XXXXXXXXXXXSQNFHFLRELPYGLGL-LTSLRELDISYNSIS-VLPDSMGCLA------ 510 + +F ELP L + L+ LD+S+N S LP+S+ L+ Sbjct: 336 FGSCSLLESLALSSNNFSGELPMDTLLKMRGLKVLDLSFNEFSGELPESLTNLSASLLTL 395 Query: 511 --KLNKFSAVGNPLIC 552 N FS P +C Sbjct: 396 DLSSNNFSGPILPNLC 411 Score = 39.3 bits (90), Expect = 0.008 Identities = 30/85 (35%), Positives = 50/85 (58%), Gaps = 3/85 (3%) Frame = +1 Query: 22 VVVLDVRSNQLK-SLPNSIGCLSKLRVLNVSGNLLQ-SLPATIEECRALEELNANFNQLT 195 +V L + N L ++P+S+G LSKLR L + N+L+ +P + + LE L +FN LT Sbjct: 442 LVSLHLSFNYLSGTIPSSLGSLSKLRDLKLWLNMLEGEIPQELMYVKTLETLILDFNDLT 501 Query: 196 -RLPDTLGFELHSLRRLSVNSNKLT 267 +P L +L +S+++N+LT Sbjct: 502 GEIPSGLS-NCTNLNWISLSNNRLT 525 Score = 33.5 bits (75), Expect = 0.44 Identities = 20/64 (31%), Positives = 36/64 (56%), Gaps = 2/64 (3%) Frame = +1 Query: 1 GIARLLNVVVLDVRSNQLKS-LPNSIGCLSKLRVLNVSGNLLQ-SLPATIEECRALEELN 174 G++ N+ + + +N+L +P IG L L +L +S N ++PA + +CR+L L+ Sbjct: 507 GLSNCTNLNWISLSNNRLTGEIPKWIGRLENLAILKLSNNSFSGNIPAELGDCRSLIWLD 566 Query: 175 ANFN 186 N N Sbjct: 567 LNTN 570 Score = 30.0 bits (66), Expect = 4.9 Identities = 41/160 (25%), Positives = 68/160 (42%), Gaps = 10/160 (6%) Frame = +1 Query: 31 LDVRSNQLK---SLPNSIGCLSKLRVLNVSGNLLQSLPATIE---ECRALEELNANFNQL 192 LD+ N L + S+G S L+ LNVS N L P + + +LE L+ + N + Sbjct: 127 LDLSRNSLSGPVTTLTSLGSCSGLKFLNVSSNTL-DFPGKVSGGLKLNSLEVLDLSANSI 185 Query: 193 TRLPDTLGFELH----SLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXX 360 + + +G+ L L+ L+++ NK++ S L LD N Sbjct: 186 SG-ANVVGWVLSDGCGELKHLAISGNKISG-DVDVSRCVNLEFLDVSSN----------- 232 Query: 361 XXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSIS 480 +F +P+ LG ++L+ LDIS N +S Sbjct: 233 -------------NFSTGIPF-LGDCSALQHLDISGNKLS 258
>VASN_MOUSE (Q9CZT5) Vasorin precursor (Protein Slit-like 2)| Length = 673 Score = 47.0 bits (110), Expect = 4e-05 Identities = 53/184 (28%), Positives = 76/184 (41%), Gaps = 3/184 (1%) Frame = +1 Query: 7 ARLLNVVVLDVRSNQLKSLPNSI-GCLSKLRVLNVSGNLLQSLP-ATIEECRALEELNAN 180 A L + +LD+ NQ+ SLP I L L L+++ N L + T R LE L Sbjct: 74 AGLPGLQLLDLSQNQITSLPGGIFQPLVNLSNLDLTANKLHEISNETFRGLRRLERLYLG 133 Query: 181 FNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXX 360 N++ + L L L + N+L LP H+ L LD N I A Sbjct: 134 KNRIRHIQPGAFDALDRLLELKLPDNELRVLP--PLHLPRLLLLDLSHNSIPALEAGILD 191 Query: 361 XXXXXXXXXSQNFHFLRELPYGL-GLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVG 537 + LR+L GL G L +L +LD+S N + +P + L L + G Sbjct: 192 TANVEALRLAGLG--LRQLDEGLFGRLLNLHDLDVSDNQLEHMPSVIQGLRGLTRLRLAG 249 Query: 538 NPLI 549 N I Sbjct: 250 NTRI 253 Score = 42.7 bits (99), Expect = 7e-04 Identities = 32/90 (35%), Positives = 44/90 (48%), Gaps = 2/90 (2%) Frame = +1 Query: 10 RLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGN--LLQSLPATIEECRALEELNANF 183 RLLN+ LDV NQL+ +P+ I L L L ++GN + Q P + AL+EL+ + Sbjct: 215 RLLNLHDLDVSDNQLEHMPSVIQGLRGLTRLRLAGNTRIAQIRPEDLAGLTALQELDVSN 274 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTSL 273 L LP L LR L+ N L Sbjct: 275 LSLQALPSDLSSLFPRLRLLAAARNPFNCL 304
>LRC33_BRARE (Q6AXL3) Leucine-rich repeat-containing protein 33 precursor| Length = 685 Score = 47.0 bits (110), Expect = 4e-05 Identities = 30/107 (28%), Positives = 56/107 (52%), Gaps = 6/107 (5%) Frame = +1 Query: 31 LDVRSNQL----KSLPNSIGCLSKLRVLNVSGNLLQS--LPATIEECRALEELNANFNQL 192 L++ +N+L K + + L++L+ L++SGN L + + +LE L + N + Sbjct: 109 LNLANNELHHGHKQVAQAFRSLTQLKTLDLSGNGLSEDMVSVLVANLSSLESLYLSRNGM 168 Query: 193 TRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCI 333 RL ++ +LH L+ L+V N L + + HM L+ L+ NC+ Sbjct: 169 QRLDESTFRDLHQLKELNVERNLLFEISGAFDHMKKLQRLNLAFNCL 215 Score = 30.8 bits (68), Expect = 2.9 Identities = 46/182 (25%), Positives = 74/182 (40%), Gaps = 18/182 (9%) Frame = +1 Query: 16 LNVVVLDVRSNQL---KSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNA--- 177 + + LDV N+L K+ S L+ L LN+S N LQ+ P I +L LN Sbjct: 375 VTIYELDVSRNRLTEIKASQTSKNKLNNLTHLNLSTNDLQNFPPMI--FTSLPNLNTLDL 432 Query: 178 --NFNQLTRLPDTLGFE-------LHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNC 330 N + + +G + SL++L + + ++P S T+L L+ N Sbjct: 433 SHNTVDVCYSSNYMGLSGCVEWSSMASLKQLYLADCSIQNVPSSAFKGTSLTHLELSNNP 492 Query: 331 ---IRAXXXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMG 501 ++ + PY T+L+ L+IS NS+S LPDS+ Sbjct: 493 NLHLKQQSLKGLANTLQHLGIGNTGLQDFDFSPY-----TNLKSLNISRNSLSKLPDSLM 547 Query: 502 CL 507 L Sbjct: 548 AL 549
>LLR1_HUMAN (Q96L50) Peptidylprolyl isomerase-like 5 (LRR-repeat protein 1)| (LRR-1) (4-1BB-mediated signaling molecule) (4-1BBlrr) Length = 414 Score = 47.0 bits (110), Expect = 4e-05 Identities = 30/80 (37%), Positives = 42/80 (52%), Gaps = 2/80 (2%) Frame = +1 Query: 79 CLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDTLGFEL--HSLRRLSVN 252 CL LR L++S N ++ LPATI + L+ELN N N L L SLR L ++ Sbjct: 175 CLKSLRKLDLSHNHIKKLPATIGDLIHLQELNLNDNHLESFSVALCHSTLQKSLRSLDLS 234 Query: 253 SNKLTSLPFSTSHMTALRAL 312 NK+ +LP + L+ L Sbjct: 235 KNKIKALPVQFCQLQELKNL 254 Score = 40.8 bits (94), Expect = 0.003 Identities = 31/95 (32%), Positives = 53/95 (55%), Gaps = 4/95 (4%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLS----KLRVLNVSGNLLQSLPATIEECRALEEL 171 I L+++ L++ N L+S ++ C S LR L++S N +++LP + + L+ L Sbjct: 196 IGDLIHLQELNLNDNHLESFSVAL-CHSTLQKSLRSLDLSKNKIKALPVQFCQLQELKNL 254 Query: 172 NANFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLP 276 + N+L + P +G +L +LR LS NKL LP Sbjct: 255 KLDDNELIQFPCKIG-QLINLRFLSAARNKLPFLP 288 Score = 30.4 bits (67), Expect = 3.7 Identities = 16/37 (43%), Positives = 23/37 (62%) Frame = +1 Query: 436 LTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPL 546 L SLR+LD+S+N I LP ++G L L + + N L Sbjct: 176 LKSLRKLDLSHNHIKKLPATIGDLIHLQELNLNDNHL 212
>TMVRN_NICGU (Q40392) TMV resistance protein N| Length = 1144 Score = 47.0 bits (110), Expect = 4e-05 Identities = 41/135 (30%), Positives = 64/135 (47%), Gaps = 29/135 (21%) Frame = +1 Query: 4 IARLLNVVVLDVRS-NQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATI------------ 144 I RL ++V L V ++L+SLP IG L LRV + S L+ P++I Sbjct: 756 ICRLKSLVSLSVSGCSKLESLPEEIGDLDNLRVFDASDTLILRPPSSIIRLNKLIILMFR 815 Query: 145 --------------EECRALEELNANFNQLT--RLPDTLGFELHSLRRLSVNSNKLTSLP 276 E +LE LN ++ L LP+ +G L SL++L ++ N LP Sbjct: 816 GFKDGVHFEFPPVAEGLHSLEYLNLSYCNLIDGGLPEEIG-SLSSLKKLDLSRNNFEHLP 874 Query: 277 FSTSHMTALRALDAR 321 S + + AL++LD + Sbjct: 875 SSIAQLGALQSLDLK 889
>DR100_ARATH (Q00874) DNA-damage-repair/toleration protein DRT100 precursor| Length = 372 Score = 46.6 bits (109), Expect = 5e-05 Identities = 40/114 (35%), Positives = 60/114 (52%), Gaps = 4/114 (3%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKS-LPNSIGCLSKLRVLNVSGNLLQ-SLPATIEECRALEELNA 177 I L ++ +LD+ N++ +P IG LSKL VLN++ N + +PA++ L+ L Sbjct: 131 ITSLASLRILDLAGNKITGEIPAEIGKLSKLAVLNLAENQMSGEIPASLTSLIELKHLEL 190 Query: 178 NFNQLTR-LPDTLGFELHSLRRLSVNSNKLT-SLPFSTSHMTALRALDARLNCI 333 N +T +P G L L R+ + N+LT S+P S S M L LD N I Sbjct: 191 TENGITGVIPADFG-SLKMLSRVLLGRNELTGSIPESISGMERLADLDLSKNHI 243 Score = 32.3 bits (72), Expect = 0.98 Identities = 37/144 (25%), Positives = 64/144 (44%), Gaps = 4/144 (2%) Frame = +1 Query: 61 LPNSIGCLSKLRVLNVSGN-LLQSLPATIEECRALEELNANFNQLT-RLPDTLGFELHSL 234 +P I L+ LR+L+++GN + +PA I + L LN NQ++ +P +L L L Sbjct: 127 IPPCITSLASLRILDLAGNKITGEIPAEIGKLSKLAVLNLAENQMSGEIPASL-TSLIEL 185 Query: 235 RRLSVNSNKLTS-LPFSTSHMTAL-RALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHFL 408 + L + N +T +P + L R L R + S+N H Sbjct: 186 KHLELTENGITGVIPADFGSLKMLSRVLLGRNELTGSIPESISGMERLADLDLSKN-HIE 244 Query: 409 RELPYGLGLLTSLRELDISYNSIS 480 +P +G + L L++ NS++ Sbjct: 245 GPIPEWMGNMKVLSLLNLDCNSLT 268
>CLV1_ARATH (Q9SYQ8) Receptor protein kinase CLAVATA1 precursor (EC 2.7.11.1)| Length = 980 Score = 46.6 bits (109), Expect = 5e-05 Identities = 32/115 (27%), Positives = 49/115 (42%), Gaps = 1/115 (0%) Frame = +1 Query: 217 FELHSLRRLSVNSNKLTS-LPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQ 393 FEL L R++ ++N +T +P S S + L ++D N I Sbjct: 501 FELKHLSRINTSANNITGGIPDSISRCSTLISVDLSRNRINGEIPKGINNVKNLGTLNIS 560 Query: 394 NFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPLICPP 558 +P G+G +TSL LD+S+N +S G N+ S GN +C P Sbjct: 561 GNQLTGSIPTGIGNMTSLTTLDLSFNDLSGRVPLGGQFLVFNETSFAGNTYLCLP 615 Score = 37.7 bits (86), Expect = 0.023 Identities = 30/98 (30%), Positives = 47/98 (47%), Gaps = 3/98 (3%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKS-LPNSIGCLSKLRVLNVSGN-LLQSLPATIEECRALEELNA 177 I+R ++ +D+ N++ +P I + L LN+SGN L S+P I +L L+ Sbjct: 524 ISRCSTLISVDLSRNRINGEIPKGINNVKNLGTLNISGNQLTGSIPTGIGNMTSLTTLDL 583 Query: 178 NFNQLT-RLPDTLGFELHSLRRLSVNSNKLTSLPFSTS 288 +FN L+ R+P LG + S N LP S Sbjct: 584 SFNDLSGRVP--LGGQFLVFNETSFAGNTYLCLPHRVS 619 Score = 35.4 bits (80), Expect = 0.12 Identities = 36/145 (24%), Positives = 66/145 (45%), Gaps = 3/145 (2%) Frame = +1 Query: 61 LPNSIGCLSKLRVLNVSG-NLLQSLPATIEECRALEELNANFNQLT-RLPDTLGFELHSL 234 +P G L+KL +L+++ L +P ++ + L L + N LT +P L L SL Sbjct: 233 VPPEFGGLTKLEILDMASCTLTGEIPTSLSNLKHLHTLFLHINNLTGHIPPELS-GLVSL 291 Query: 235 RRLSVNSNKLTS-LPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHFLR 411 + L ++ N+LT +P S ++ + ++ N + +F Sbjct: 292 KSLDLSINQLTGEIPQSFINLGNITLINLFRNNLYGQIPEAIGELPKLEVFEVWENNFTL 351 Query: 412 ELPYGLGLLTSLRELDISYNSISVL 486 +LP LG +L +LD+S N ++ L Sbjct: 352 QLPANLGRNGNLIKLDVSDNHLTGL 376
>LRC15_HUMAN (Q8TF66) Leucine-rich repeat-containing protein 15 precursor (hLib)| Length = 581 Score = 46.6 bits (109), Expect = 5e-05 Identities = 54/187 (28%), Positives = 80/187 (42%), Gaps = 15/187 (8%) Frame = +1 Query: 31 LDVRSNQLKSLPNSI--GCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLP 204 L + +N+L+ LP + G S +L S LLQ PA +C L+EL + N L +P Sbjct: 106 LSLANNKLQVLPIGLFQGLDSLESLLLSSNQLLQIQPAHFSQCSNLKELQLHGNHLEYIP 165 Query: 205 DTLGFELHSLRRLSVNSNKLTSL-PFSTSH---MTALRALDARLNCIRAXXXXXXXXXXX 372 D L L +L++ N LT + P H + LR + RL I Sbjct: 166 DGAFDHLVGLTKLNLGKNSLTHISPRVFQHLGNLQVLRLYENRLTDIPMGTFDGLVNLQE 225 Query: 373 XXXXXSQNFHFLRELPYGLGLLT--------SLRELDISYNSISVLPDSMGC-LAKLNKF 525 +Q +GLL+ +L+ L +S N IS LP S+ L +LN+ Sbjct: 226 LALQQNQ-----------IGLLSPGLFHNNHNLQRLYLSNNHISQLPPSIFMQLPQLNRL 274 Query: 526 SAVGNPL 546 + GN L Sbjct: 275 TLFGNSL 281 Score = 38.1 bits (87), Expect = 0.018 Identities = 25/92 (27%), Positives = 49/92 (53%), Gaps = 2/92 (2%) Frame = +1 Query: 7 ARLLNVVVLDVRSNQLKSL-PNSIGCLSKLRVLNVSGNLLQSLPATIEECRA-LEELNAN 180 + L + VL + NQ+ + P + L++LR L++ N LQ L + A L+ ++ Sbjct: 314 SNLRQLQVLILSRNQISFISPGAFNGLTELRELSLHTNALQDLDGNVFRMLANLQNISLQ 373 Query: 181 FNQLTRLPDTLGFELHSLRRLSVNSNKLTSLP 276 N+L +LP + ++ L + + +N+L +LP Sbjct: 374 NNRLRQLPGNIFANVNGLMAIQLQNNQLENLP 405
>LRC59_BOVIN (Q5E9X4) Leucine-rich repeat-containing protein 59| Length = 306 Score = 46.6 bits (109), Expect = 5e-05 Identities = 32/100 (32%), Positives = 56/100 (56%), Gaps = 1/100 (1%) Frame = +1 Query: 31 LDVRSNQLKSLP-NSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPD 207 LD+ + L +P + L K VL++S N L +LP+ L +L+ + N+L +LP Sbjct: 20 LDLSLSDLNEVPVKELAALPKATVLDLSCNKLTTLPSDFCGLTHLVKLDLSKNKLRQLPA 79 Query: 208 TLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLN 327 G L +L+ L + +N+L +LP S + + +L+ LD + N Sbjct: 80 DFG-RLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDN 118 Score = 42.7 bits (99), Expect = 7e-04 Identities = 30/87 (34%), Positives = 46/87 (52%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 +A L VLD+ N+L +LP+ L+ L L++S N L+ LPA L+ L+ Sbjct: 35 LAALPKATVLDLSCNKLTTLPSDFCGLTHLVKLDLSKNKLRQLPADFGRLVNLQHLDLLN 94 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKL 264 N+L LP + +L SL+ L + N L Sbjct: 95 NRLVTLPVSFA-QLKSLKWLDLKDNPL 120 Score = 37.7 bits (86), Expect = 0.023 Identities = 35/127 (27%), Positives = 48/127 (37%) Frame = +1 Query: 166 ELNANFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXX 345 EL+ + + L +P L L ++ NKLT+LP +T L LD N Sbjct: 19 ELDLSLSDLNEVPVKELAALPKATVLDLSCNKLTTLPSDFCGLTHLVKLDLSKN------ 72 Query: 346 XXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKF 525 LR+LP G L +L+ LD+ N + LP S L L Sbjct: 73 -------------------KLRQLPADFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWL 113 Query: 526 SAVGNPL 546 NPL Sbjct: 114 DLKDNPL 120
>CHAO_TRICA (P82963) Chaoptin (Photoreceptor cell-specific membrane protein)| (Fragment) Length = 782 Score = 46.2 bits (108), Expect = 7e-05 Identities = 49/205 (23%), Positives = 83/205 (40%), Gaps = 29/205 (14%) Frame = +1 Query: 19 NVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPAT---IEECRALEELNANFNQ 189 N+ ++D N+L+SLP+++ + L L+VS NLL LP T + + L EL+ ++N Sbjct: 321 NLRIVDFSHNRLRSLPDNLFRETGLERLDVSHNLLGKLPLTSLSLASAQTLSELDLSWNS 380 Query: 190 LTRLP------------------------DTLGFE-LHSLRRLSVNSNKLTSLPFSTSHM 294 ++ L D F+ + L L++ N +L + Sbjct: 381 ISSLSHGGQLARFKCLSWLDLSYNRLGQIDAGTFKGIPRLASLNLGHNSQLTLEINGLSF 440 Query: 295 TALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHFLRELPYGL-GLLTSLRELDISYN 471 L LN S F+ L + + G ++SLR L++ YN Sbjct: 441 QGLEYTLLHLNLDNVSLSQVPALSTPNLLSLSLAFNSLPTVALEVAGNISSLRYLNLDYN 500 Query: 472 SISVLPDSMGCLAKLNKFSAVGNPL 546 +S +P L +L S GNP+ Sbjct: 501 DLSAVPIVTHSLTELRHLSLEGNPI 525 Score = 44.3 bits (103), Expect = 2e-04 Identities = 42/149 (28%), Positives = 66/149 (44%), Gaps = 4/149 (2%) Frame = +1 Query: 52 LKSLPNSIGCLSKLRVLNVSGNLLQSLPA-TIEECRALEELNANFNQLTRLPDTLGFELH 228 L + + G + L+VL++S N L L T + L+ L+ + N+++ +P+ L L Sbjct: 261 LNATKDLFGNMPHLQVLDLSHNSLYELDFDTFRNTKKLQWLDTSHNRISEIPNDLFRFLG 320 Query: 229 SLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHFL 408 +LR + + N+L SLP + T L LD N L Sbjct: 321 NLRIVDFSHNRLRSLPDNLFRETGLERLDVSHN-------------------------LL 355 Query: 409 RELP---YGLGLLTSLRELDISYNSISVL 486 +LP L +L ELD+S+NSIS L Sbjct: 356 GKLPLTSLSLASAQTLSELDLSWNSISSL 384 Score = 32.7 bits (73), Expect = 0.75 Identities = 41/155 (26%), Positives = 63/155 (40%), Gaps = 3/155 (1%) Frame = +1 Query: 73 IGCLSKLRVLNVSGNLLQSLPATIEEC--RALEELNANFNQLTRLPDTLGFELHSLRRLS 246 +G L ++VL++S N + S+ +L +L N+L L + L+ L Sbjct: 219 LGGLQNIKVLDLSFNNITSVAKQFFRPVELSLMQLYLGHNKLLNATKDLFGNMPHLQVLD 278 Query: 247 VNSNKLTSLPFSTSHMTA-LRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHFLRELPY 423 ++ N L L F T T L+ LD N I + + + LR LP Sbjct: 279 LSHNSLYELDFDTFRNTKKLQWLDTSHNRI-SEIPNDLFRFLGNLRIVDFSHNRLRSLPD 337 Query: 424 GLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFS 528 L T L LD+S+N + LP + LA S Sbjct: 338 NLFRETGLERLDVSHNLLGKLPLTSLSLASAQTLS 372
>LRC59_HUMAN (Q96AG4) Leucine-rich repeat-containing protein 59| Length = 307 Score = 46.2 bits (108), Expect = 7e-05 Identities = 32/100 (32%), Positives = 55/100 (55%), Gaps = 1/100 (1%) Frame = +1 Query: 31 LDVRSNQLKSLP-NSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPD 207 LD+ + L +P + L K +L++S N L +LP+ L +L+ + N+L +LP Sbjct: 20 LDLSLSDLNEVPVKELAALPKATILDLSCNKLTTLPSDFCGLTHLVKLDLSKNKLQQLPA 79 Query: 208 TLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLN 327 G L +L+ L + +NKL +LP S + + L+ LD + N Sbjct: 80 DFG-RLVNLQHLDLLNNKLVTLPVSFAQLKNLKWLDLKDN 118 Score = 42.7 bits (99), Expect = 7e-04 Identities = 29/87 (33%), Positives = 46/87 (52%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 +A L +LD+ N+L +LP+ L+ L L++S N LQ LPA L+ L+ Sbjct: 35 LAALPKATILDLSCNKLTTLPSDFCGLTHLVKLDLSKNKLQQLPADFGRLVNLQHLDLLN 94 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKL 264 N+L LP + +L +L+ L + N L Sbjct: 95 NKLVTLPVSFA-QLKNLKWLDLKDNPL 120 Score = 36.6 bits (83), Expect = 0.052 Identities = 34/127 (26%), Positives = 48/127 (37%) Frame = +1 Query: 166 ELNANFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXX 345 EL+ + + L +P L L ++ NKLT+LP +T L LD N Sbjct: 19 ELDLSLSDLNEVPVKELAALPKATILDLSCNKLTTLPSDFCGLTHLVKLDLSKNK----- 73 Query: 346 XXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKF 525 L++LP G L +L+ LD+ N + LP S L L Sbjct: 74 --------------------LQQLPADFGRLVNLQHLDLLNNKLVTLPVSFAQLKNLKWL 113 Query: 526 SAVGNPL 546 NPL Sbjct: 114 DLKDNPL 120
>ALS_HUMAN (P35858) Insulin-like growth factor-binding protein complex acid| labile chain precursor (ALS) Length = 605 Score = 46.2 bits (108), Expect = 7e-05 Identities = 49/161 (30%), Positives = 66/161 (40%), Gaps = 3/161 (1%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSLP-NSIGCLSKLRVLNVSGNLLQSLP-ATIEECRALEELNANFN 186 L N+ L + NQL+SL + L L +S N L L E +L +LN +N Sbjct: 121 LENLCHLHLERNQLRSLALGTFAHTPALASLGLSNNRLSRLEDGLFEGLGSLWDLNLGWN 180 Query: 187 QLTRLPDTLGFELHSLRRLSVNSNKLTSL-PFSTSHMTALRALDARLNCIRAXXXXXXXX 363 L LPD L SLR L + N+L L P S + LR LD N +RA Sbjct: 181 SLAVLPDAAFRGLGSLRELVLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQ 240 Query: 364 XXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVL 486 P L +LR LD+S+N ++ L Sbjct: 241 LPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVAGL 281 Score = 35.0 bits (79), Expect = 0.15 Identities = 36/114 (31%), Positives = 50/114 (43%), Gaps = 26/114 (22%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSLPNSI-GCLSKLRVLNVSGNLLQSL-PAT--------------- 141 L NV V+++ N L++LP + L KL L++ G+ L + P T Sbjct: 361 LTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDN 420 Query: 142 ----IEE-----CRALEELNANFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLP 276 IEE L EL+ NQLT LP L L L L ++ N+L LP Sbjct: 421 GLVGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQGLGKLEYLLLSRNRLAELP 474
>LRC59_RAT (Q5RJR8) Leucine-rich repeat-containing protein 59 (Protein p34)| Length = 307 Score = 45.8 bits (107), Expect = 9e-05 Identities = 32/100 (32%), Positives = 55/100 (55%), Gaps = 1/100 (1%) Frame = +1 Query: 31 LDVRSNQLKSLP-NSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPD 207 LD+ + L +P + L K VL++S N L +LP+ L +L+ + N+L +LP Sbjct: 20 LDLSLSDLNEVPVKELAALPKATVLDLSCNKLSTLPSDFCGLTHLVKLDLSKNKLQQLPA 79 Query: 208 TLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLN 327 G L +L+ L + +N+L +LP S + + L+ LD + N Sbjct: 80 DFG-RLVNLQHLDLLNNRLVTLPVSFAQLKNLKWLDLKDN 118 Score = 43.5 bits (101), Expect = 4e-04 Identities = 30/87 (34%), Positives = 46/87 (52%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 +A L VLD+ N+L +LP+ L+ L L++S N LQ LPA L+ L+ Sbjct: 35 LAALPKATVLDLSCNKLSTLPSDFCGLTHLVKLDLSKNKLQQLPADFGRLVNLQHLDLLN 94 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKL 264 N+L LP + +L +L+ L + N L Sbjct: 95 NRLVTLPVSFA-QLKNLKWLDLKDNPL 120 Score = 34.7 bits (78), Expect = 0.20 Identities = 33/127 (25%), Positives = 48/127 (37%) Frame = +1 Query: 166 ELNANFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXX 345 EL+ + + L +P L L ++ NKL++LP +T L LD N Sbjct: 19 ELDLSLSDLNEVPVKELAALPKATVLDLSCNKLSTLPSDFCGLTHLVKLDLSKNK----- 73 Query: 346 XXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKF 525 L++LP G L +L+ LD+ N + LP S L L Sbjct: 74 --------------------LQQLPADFGRLVNLQHLDLLNNRLVTLPVSFAQLKNLKWL 113 Query: 526 SAVGNPL 546 NPL Sbjct: 114 DLKDNPL 120
>LRC59_MOUSE (Q922Q8) Leucine-rich repeat-containing protein 59| Length = 307 Score = 45.8 bits (107), Expect = 9e-05 Identities = 32/100 (32%), Positives = 55/100 (55%), Gaps = 1/100 (1%) Frame = +1 Query: 31 LDVRSNQLKSLP-NSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPD 207 LD+ + L +P + L K VL++S N L +LP+ L +L+ + N+L +LP Sbjct: 20 LDLSLSDLNEVPVKELAALPKATVLDLSCNKLSTLPSDFCGLTHLVKLDLSKNKLQQLPA 79 Query: 208 TLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLN 327 G L +L+ L + +N+L +LP S + + L+ LD + N Sbjct: 80 DFG-RLVNLQHLDLLNNRLVTLPVSFAQLKNLKWLDLKDN 118 Score = 43.5 bits (101), Expect = 4e-04 Identities = 30/87 (34%), Positives = 46/87 (52%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 +A L VLD+ N+L +LP+ L+ L L++S N LQ LPA L+ L+ Sbjct: 35 LAALPKATVLDLSCNKLSTLPSDFCGLTHLVKLDLSKNKLQQLPADFGRLVNLQHLDLLN 94 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKL 264 N+L LP + +L +L+ L + N L Sbjct: 95 NRLVTLPVSFA-QLKNLKWLDLKDNPL 120 Score = 34.7 bits (78), Expect = 0.20 Identities = 33/127 (25%), Positives = 48/127 (37%) Frame = +1 Query: 166 ELNANFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXX 345 EL+ + + L +P L L ++ NKL++LP +T L LD N Sbjct: 19 ELDLSLSDLNEVPVKELAALPKATVLDLSCNKLSTLPSDFCGLTHLVKLDLSKNK----- 73 Query: 346 XXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKF 525 L++LP G L +L+ LD+ N + LP S L L Sbjct: 74 --------------------LQQLPADFGRLVNLQHLDLLNNRLVTLPVSFAQLKNLKWL 113 Query: 526 SAVGNPL 546 NPL Sbjct: 114 DLKDNPL 120
>LRIG3_MOUSE (Q6P1C6) Leucine-rich repeats and immunoglobulin-like domains| protein 3 precursor Length = 1117 Score = 45.4 bits (106), Expect = 1e-04 Identities = 35/108 (32%), Positives = 56/108 (51%), Gaps = 3/108 (2%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSLPNS-IGCLSKLRVLNVSGNLLQSL-PATIEECRALEELNANFN 186 L N+ VL + N L + + L LR L++S N + + P E C+ L EL+ FN Sbjct: 262 LSNMEVLQLDHNNLTEITKGWLYGLLMLRELHLSQNAINRISPDAWEFCQKLSELDLTFN 321 Query: 187 QLTRLPDTLGFELHSLRRLSVNSNKLTSL-PFSTSHMTALRALDARLN 327 L+RL D+ L L L + +NK++ + + +T+L+ LD R N Sbjct: 322 HLSRLDDSSFLGLSLLNALHIGNNKVSYIADCAFRGLTSLKTLDLRNN 369 Score = 40.4 bits (93), Expect = 0.004 Identities = 23/91 (25%), Positives = 54/91 (59%), Gaps = 1/91 (1%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQS-LPATIEECRALEELNAN 180 ++ L ++ + + +N+L+++PN + +R L+++GN + LP +E ++LE L+ + Sbjct: 94 LSHLQSLQEVKLNNNELETIPNLGSISANIRQLSLAGNAIDKILPEQLEAFQSLETLDLS 153 Query: 181 FNQLTRLPDTLGFELHSLRRLSVNSNKLTSL 273 N ++ L F L+ L +N+N+++S+ Sbjct: 154 NNNISEL--RTAFPPLQLKYLYINNNRVSSM 182 Score = 36.6 bits (83), Expect = 0.052 Identities = 37/160 (23%), Positives = 69/160 (43%), Gaps = 2/160 (1%) Frame = +1 Query: 22 VVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPA-TIEECRALEELNANFNQLTR 198 ++VL + N++ ++P + L +L+ L ++ N ++++ T + AL+ L N +T+ Sbjct: 194 LLVLKLNRNRISAIPPKMFKLPQLQHLELNRNKIKNVDGLTFQGLGALKSLKMQRNGVTK 253 Query: 199 LPDTLGFELHSLRRLSVNSNKLTSLPFSTSH-MTALRALDARLNCIRAXXXXXXXXXXXX 375 L D + L ++ L ++ N LT + + + LR L N I Sbjct: 254 LMDGAFWGLSNMEVLQLDHNNLTEITKGWLYGLLMLRELHLSQNAIN------------- 300 Query: 376 XXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDS 495 R P L ELD+++N +S L DS Sbjct: 301 -----------RISPDAWEFCQKLSELDLTFNHLSRLDDS 329
>ALS_PAPHA (O02833) Insulin-like growth factor-binding protein complex acid| labile chain precursor (ALS) Length = 605 Score = 45.4 bits (106), Expect = 1e-04 Identities = 48/161 (29%), Positives = 65/161 (40%), Gaps = 3/161 (1%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSLP-NSIGCLSKLRVLNVSGNLLQSLP-ATIEECRALEELNANFN 186 L N+ L + NQL+SL + L +L +S N L L E L +LN +N Sbjct: 121 LENLCHLHLERNQLRSLAVGTFAYTPALALLGLSNNRLSRLEDGLFEGLGNLWDLNLGWN 180 Query: 187 QLTRLPDTLGFELHSLRRLSVNSNKLTSL-PFSTSHMTALRALDARLNCIRAXXXXXXXX 363 L LPD L LR L + N+L L P S + LR LD N +RA Sbjct: 181 SLAVLPDAAFRGLGGLRELVLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFAQ 240 Query: 364 XXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVL 486 P L +LR LD+S+N ++ L Sbjct: 241 LPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVAGL 281 Score = 35.0 bits (79), Expect = 0.15 Identities = 36/114 (31%), Positives = 50/114 (43%), Gaps = 26/114 (22%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSLPNSI-GCLSKLRVLNVSGNLLQSL-PAT--------------- 141 L NV V+++ N L++LP + L KL L++ G+ L + P T Sbjct: 361 LTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFAGLSGLRRLFLKDN 420 Query: 142 ----IEE-----CRALEELNANFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLP 276 IEE L EL+ NQLT LP L L L L ++ N+L LP Sbjct: 421 GLVGIEEQSLWGLAELLELDLTSNQLTHLPHQLFQGLGKLEYLLLSHNRLAELP 474
>LUM_COTJA (Q9DE67) Lumican precursor (Keratan sulfate proteoglycan lumican)| (KSPG lumican) Length = 343 Score = 45.1 bits (105), Expect = 1e-04 Identities = 34/113 (30%), Positives = 63/113 (55%), Gaps = 4/113 (3%) Frame = +1 Query: 13 LLNVVVLDVRSNQLK--SLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFN 186 L+N+ V+ +++NQLK S+ + L+ L L++S N L LP + +L L + N Sbjct: 163 LVNLTVIHLQNNQLKADSISGAFKGLNSLLYLDLSFNQLTKLPTGLPH--SLLMLYFDNN 220 Query: 187 QLTRLPDTLGFELHSLRRLSVNSNKLT--SLPFSTSHMTALRALDARLNCIRA 339 Q++ +PD +L+ L ++ NKLT +P + ++T+L LD N +++ Sbjct: 221 QISNIPDEYFQGFKTLQYLRLSHNKLTDSGIPGNVFNITSLVELDLSFNQLKS 273 Score = 38.1 bits (87), Expect = 0.018 Identities = 36/144 (25%), Positives = 64/144 (44%), Gaps = 2/144 (1%) Frame = +1 Query: 64 PNSIGCLSKLRVLNVSGNLLQ--SLPATIEECRALEELNANFNQLTRLPDTLGFELHSLR 237 P ++ L L V+++ N L+ S+ + +L L+ +FNQLT+LP L HSL Sbjct: 157 PGALEGLVNLTVIHLQNNQLKADSISGAFKGLNSLLYLDLSFNQLTKLPTGLP---HSLL 213 Query: 238 RLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHFLREL 417 L ++N+++++P + + L S N + Sbjct: 214 MLYFDNNQISNIP--DEYFQGFKTLQ--------------------YLRLSHNKLTDSGI 251 Query: 418 PYGLGLLTSLRELDISYNSISVLP 489 P + +TSL ELD+S+N + +P Sbjct: 252 PGNVFNITSLVELDLSFNQLKSIP 275
>LUM_CHICK (P51890) Lumican precursor (Keratan sulfate proteoglycan lumican)| (KSPG lumican) Length = 343 Score = 45.1 bits (105), Expect = 1e-04 Identities = 34/113 (30%), Positives = 63/113 (55%), Gaps = 4/113 (3%) Frame = +1 Query: 13 LLNVVVLDVRSNQLK--SLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFN 186 L+N+ V+ +++NQLK S+ + L+ L L++S N L LP + +L L + N Sbjct: 163 LVNLTVIHLQNNQLKTDSISGAFKGLNSLLYLDLSFNQLTKLPTGLPH--SLLMLYFDNN 220 Query: 187 QLTRLPDTLGFELHSLRRLSVNSNKLT--SLPFSTSHMTALRALDARLNCIRA 339 Q++ +PD +L+ L ++ NKLT +P + ++T+L LD N +++ Sbjct: 221 QISNIPDEYFQGFKTLQYLRLSHNKLTDSGIPGNVFNITSLVELDLSFNQLKS 273 Score = 38.1 bits (87), Expect = 0.018 Identities = 36/144 (25%), Positives = 64/144 (44%), Gaps = 2/144 (1%) Frame = +1 Query: 64 PNSIGCLSKLRVLNVSGNLLQ--SLPATIEECRALEELNANFNQLTRLPDTLGFELHSLR 237 P ++ L L V+++ N L+ S+ + +L L+ +FNQLT+LP L HSL Sbjct: 157 PGALEGLVNLTVIHLQNNQLKTDSISGAFKGLNSLLYLDLSFNQLTKLPTGLP---HSLL 213 Query: 238 RLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHFLREL 417 L ++N+++++P + + L S N + Sbjct: 214 MLYFDNNQISNIP--DEYFQGFKTLQ--------------------YLRLSHNKLTDSGI 251 Query: 418 PYGLGLLTSLRELDISYNSISVLP 489 P + +TSL ELD+S+N + +P Sbjct: 252 PGNVFNITSLVELDLSFNQLKSIP 275
>RGA2_SOLBU (Q7XBQ9) Disease resistance protein RGA2 (RGA2-blb) (Blight| resistance protein RPI) Length = 970 Score = 45.1 bits (105), Expect = 1e-04 Identities = 33/105 (31%), Positives = 59/105 (56%), Gaps = 2/105 (1%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 + + +++ VL++ + LP+SIG L LR LN+ G+ ++SLP + + + L+ L+ + Sbjct: 522 LEKFISLRVLNLGDSTFNKLPSSIGDLVHLRYLNLYGSGMRSLPKQLCKLQNLQTLDLQY 581 Query: 184 -NQLTRLPDTLGFELHSLRRLSVN-SNKLTSLPFSTSHMTALRAL 312 +L LP +L SLR L ++ S LT +P +T L+ L Sbjct: 582 CTKLCCLPKETS-KLGSLRNLLLDGSQSLTCMPPRIGSLTCLKTL 625
>Y4FR_RHISN (P55456) Hypothetical 60.5 kDa protein y4fR| Length = 546 Score = 45.1 bits (105), Expect = 1e-04 Identities = 34/84 (40%), Positives = 46/84 (54%) Frame = +1 Query: 31 LDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDT 210 L+ N+L LP+ L +L NV N L +LP + ALE L A +NQLTRLP+ Sbjct: 129 LEASENRLTRLPDLPAGLQRL---NVENNRLTNLPEPLPA--ALEWLGAGYNQLTRLPEM 183 Query: 211 LGFELHSLRRLSVNSNKLTSLPFS 282 + E L L +N+LTS+P S Sbjct: 184 IPPE---LIWLGARNNQLTSVPES 204 Score = 35.4 bits (80), Expect = 0.12 Identities = 25/70 (35%), Positives = 33/70 (47%) Frame = +1 Query: 115 NLLQSLPATIEECRALEELNANFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHM 294 + L P +I L LN N NQL LPDTL +L L + N+LT LP + + Sbjct: 90 SFLSLTPLSIPLVSGLRRLNVNNNQLGDLPDTLP---GTLLELEASENRLTRLPDLPAGL 146 Query: 295 TALRALDARL 324 L + RL Sbjct: 147 QRLNVENNRL 156
>CCR4_YEAST (P31384) Glucose-repressible alcohol dehydrogenase transcriptional| effector (EC 3.1.-.-) (Cytoplasmic deadenylase) (Carbon catabolite repressor protein 4) Length = 837 Score = 44.3 bits (103), Expect = 2e-04 Identities = 32/78 (41%), Positives = 40/78 (51%) Frame = +1 Query: 31 LDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDT 210 L + N L LP I LS LRVL++S N L SLPA + C L+ N +T LP Sbjct: 362 LYLNGNSLTELPAEIKNLSNLRVLDLSHNRLTSLPAELGSCFQLKYFYFFDNMVTTLPWE 421 Query: 211 LGFELHSLRRLSVNSNKL 264 G L +L+ L V N L Sbjct: 422 FG-NLCNLQFLGVEGNPL 438 Score = 40.0 bits (92), Expect = 0.005 Identities = 30/99 (30%), Positives = 49/99 (49%) Frame = +1 Query: 31 LDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDT 210 LD+ + Q+ ++ +I L L ++GN L LPA I+ L L+ + N+LT LP Sbjct: 339 LDLSNLQIFNISANIFKYDFLTRLYLNGNSLTELPAEIKNLSNLRVLDLSHNRLTSLPAE 398 Query: 211 LGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLN 327 LG L+ N +T+LP+ ++ L+ L N Sbjct: 399 LG-SCFQLKYFYFFDNMVTTLPWEFGNLCNLQFLGVEGN 436 Score = 33.5 bits (75), Expect = 0.44 Identities = 19/57 (33%), Positives = 31/57 (54%) Frame = +1 Query: 394 NFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPLICPPMD 564 N + L ELP + L++LR LD+S+N ++ LP +G +L F N + P + Sbjct: 365 NGNSLTELPAEIKNLSNLRVLDLSHNRLTSLPAELGSCFQLKYFYFFDNMVTTLPWE 421 Score = 32.0 bits (71), Expect = 1.3 Identities = 20/65 (30%), Positives = 31/65 (47%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 I L N+ VLD+ N+L SLP +G +L+ N++ +LP L+ L Sbjct: 376 IKNLSNLRVLDLSHNRLTSLPAELGSCFQLKYFYFFDNMVTTLPWEFGNLCNLQFLGVEG 435 Query: 184 NQLTR 198 N L + Sbjct: 436 NPLEK 440
>OMD_MOUSE (O35103) Osteomodulin precursor (Osteoadherin) (OSAD) (Keratan| sulfate proteoglycan osteomodulin) (KSPG osteomodulin) Length = 423 Score = 44.3 bits (103), Expect = 2e-04 Identities = 30/111 (27%), Positives = 56/111 (50%), Gaps = 3/111 (2%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSL---PNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 L+NV +LD+ N L ++ + KL LN+ N L+S+P + +L L+ Sbjct: 185 LVNVTMLDLCYNHLSDSMLKEKTLSKMEKLMQLNLCNNRLESMPLGLPS--SLMYLSLEN 242 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIR 336 N ++ +PD +L L L ++ NKL +P+ +++ L L+ N ++ Sbjct: 243 NSISSIPDNYFDKLPKLHALRISHNKLEDIPYDIFNLSNLIELNVGHNKLK 293 Score = 33.9 bits (76), Expect = 0.34 Identities = 46/183 (25%), Positives = 77/183 (42%), Gaps = 4/183 (2%) Frame = +1 Query: 31 LDVRSNQLKSLPNSIGC---LSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRL 201 +++ N++KS G LS L+ L++ N L+ P + ++LE L +N+++ L Sbjct: 120 INLSHNKIKSQKIDYGVFAKLSNLQQLHLEHNNLEEFPFPLP--KSLERLLLGYNEISIL 177 Query: 202 PDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXX 381 P L ++ L + N L+ ++ + L +LN Sbjct: 178 PTNAMDGLVNVTMLDLCYNHLSDSMLKEKTLSKMEKL-MQLNLCN--------------- 221 Query: 382 XXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDS-MGCLAKLNKFSAVGNPLICPP 558 + L +P LGL +SL L + NSIS +PD+ L KL+ N L P Sbjct: 222 ------NRLESMP--LGLPSSLMYLSLENNSISSIPDNYFDKLPKLHALRISHNKLEDIP 273 Query: 559 MDI 567 DI Sbjct: 274 YDI 276
>LRC49_MOUSE (Q91YK0) Leucine-rich repeat-containing protein 49| Length = 686 Score = 44.3 bits (103), Expect = 2e-04 Identities = 32/89 (35%), Positives = 49/89 (55%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 + L N+ VLD+ NQ+ + N + L LRVLN++ NLL + + +L ELN Sbjct: 174 LENLKNLDVLDLHGNQITKIEN-VNHLCDLRVLNLARNLLSHVD-NLNGLDSLTELNLRH 231 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTS 270 NQ+T + D L L+RL ++ N +TS Sbjct: 232 NQITFVRDV--DNLPCLQRLFLSFNNITS 258
>LRIG2_HUMAN (O94898) Leucine-rich repeats and immunoglobulin-like domains| protein 2 precursor (LIG-2) Length = 1065 Score = 43.9 bits (102), Expect = 3e-04 Identities = 34/108 (31%), Positives = 57/108 (52%), Gaps = 3/108 (2%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSLPNS-IGCLSKLRVLNVSGNLLQSL-PATIEECRALEELNANFN 186 L N+ L++ N L + + L L+ L VS N ++ + P E C+ L EL+ ++N Sbjct: 262 LNNMEELELEHNNLTRVNKGWLYGLRMLQQLYVSQNAIERISPDAWEFCQRLSELDLSYN 321 Query: 187 QLTRLPDTLGFELHSLRRLSVNSNKLTSLPFST-SHMTALRALDARLN 327 QLTRL ++ L L RL++ N++T + ++ L+ LD R N Sbjct: 322 QLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLDLRNN 369 Score = 33.9 bits (76), Expect = 0.34 Identities = 40/172 (23%), Positives = 71/172 (41%), Gaps = 5/172 (2%) Frame = +1 Query: 19 NVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPA-TIEECRALEELNANFNQLT 195 +++V+ + N++ +P I L L+ L + N ++ + T + +L L N ++ Sbjct: 193 SLLVVKLNRNRMSMIPPKIFKLPHLQFLELKRNRIKIVEGLTFQGLDSLRSLKMQRNGIS 252 Query: 196 RLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXX 375 +L D F L+++ L + N LT + + + LR L Sbjct: 253 KLKDGAFFGLNNMEELELEHNNLTRV--NKGWLYGLRMLQQ------------------- 291 Query: 376 XXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDS----MGCLAKLN 519 SQN R P L ELD+SYN ++ L +S + L +LN Sbjct: 292 -LYVSQNA-IERISPDAWEFCQRLSELDLSYNQLTRLDESAFVGLSLLERLN 341
>LRIG2_MOUSE (Q52KR2) Leucine-rich repeats and immunoglobulin-like domains| protein 2 precursor Length = 1054 Score = 43.9 bits (102), Expect = 3e-04 Identities = 34/110 (30%), Positives = 58/110 (52%), Gaps = 3/110 (2%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSLPNS-IGCLSKLRVLNVSGNLLQSL-PATIEECRALEELNANFN 186 L N+ L++ N L + + L L+ L +S N ++ + P E C+ L EL+ ++N Sbjct: 261 LNNMEELELEHNNLTGVNKGWLYGLRMLQQLYMSQNAIEKISPDAWEFCQRLSELDLSYN 320 Query: 187 QLTRLPDTLGFELHSLRRLSVNSNKLTSLPFST-SHMTALRALDARLNCI 333 QLTRL ++ L L RL++ N++T + ++ L+ LD R N I Sbjct: 321 QLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLDLRNNDI 370
>TLR11_MOUSE (Q6R5P0) Toll-like receptor 11 precursor| Length = 926 Score = 43.9 bits (102), Expect = 3e-04 Identities = 54/189 (28%), Positives = 82/189 (43%), Gaps = 11/189 (5%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSL--PATIEECRALEELNANFN 186 LL++ L + ++ +P S+ S+LR L++ N +Q++ I +ALE L+ + N Sbjct: 263 LLHLHFLSLVGTGIEKVPASLTGYSELRALDLGKNQIQNILENGEIPGYKALEFLSLHDN 322 Query: 187 QLTRLPDTLGFELHSLRRLSVNSNKL---TSLP---FSTSHMTALRALDARLN--CIRAX 342 L LP L L++L+++ NKL LP FST+ L+ LD N C Sbjct: 323 HLQTLPTRFLHTLPQLQKLNLSMNKLGPILELPEGLFSTN----LKVLDLSYNQLCDVPH 378 Query: 343 XXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVL-PDSMGCLAKLN 519 N L L L LR LD+S+N I VL P + L L Sbjct: 379 GALSLLSQLQELWLSGNNISSLSN--ESLQGLRQLRTLDLSWNQIKVLKPGWLSHLPALT 436 Query: 520 KFSAVGNPL 546 + +G L Sbjct: 437 TLNLLGTYL 445 Score = 40.8 bits (94), Expect = 0.003 Identities = 42/162 (25%), Positives = 79/162 (48%), Gaps = 5/162 (3%) Frame = +1 Query: 16 LNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLT 195 L+ ++LD LK+L + L L L++ G ++ +PA++ L L+ NQ+ Sbjct: 243 LHSLILD--GTPLKALDLTDSGLLHLHFLSLVGTGIEKVPASLTGYSELRALDLGKNQIQ 300 Query: 196 RL---PDTLGFELHSLRRLSVNSNKLTSLPFSTSH-MTALRALDARLNCIRAXXXXXXXX 363 + + G++ +L LS++ N L +LP H + L+ L+ +N + Sbjct: 301 NILENGEIPGYK--ALEFLSLHDNHLQTLPTRFLHTLPQLQKLNLSMNKLGPILELPEGL 358 Query: 364 XXXXXXXXSQNFHFLRELPYG-LGLLTSLRELDISYNSISVL 486 +++ L ++P+G L LL+ L+EL +S N+IS L Sbjct: 359 FSTNLKVLDLSYNQLCDVPHGALSLLSQLQELWLSGNNISSL 400
>LRC59_XENTR (Q6NX28) Leucine-rich repeat-containing protein 59| Length = 308 Score = 43.9 bits (102), Expect = 3e-04 Identities = 29/103 (28%), Positives = 54/103 (52%), Gaps = 1/103 (0%) Frame = +1 Query: 31 LDVRSNQLKSLP-NSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPD 207 LD+ + L +P + + K L++S N L SLP + L+ + NQ+ +LP Sbjct: 20 LDLSLSDLSEVPVRDLVAIPKATALDLSCNKLTSLPDDFCNLSYIVRLDLSKNQIAQLPS 79 Query: 208 TLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIR 336 G L +L+ L + N++ +LP S + + +L+ LD + N ++ Sbjct: 80 EFG-RLVNLQHLDLLQNRIVALPVSFAQLKSLKWLDLKDNPLK 121 Score = 36.2 bits (82), Expect = 0.068 Identities = 33/127 (25%), Positives = 49/127 (38%) Frame = +1 Query: 166 ELNANFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXX 345 EL+ + + L+ +P + L ++ NKLTSLP +++ + LD N I Sbjct: 19 ELDLSLSDLSEVPVRDLVAIPKATALDLSCNKLTSLPDDFCNLSYIVRLDLSKNQIA--- 75 Query: 346 XXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKF 525 +LP G L +L+ LD+ N I LP S L L Sbjct: 76 ----------------------QLPSEFGRLVNLQHLDLLQNRIVALPVSFAQLKSLKWL 113 Query: 526 SAVGNPL 546 NPL Sbjct: 114 DLKDNPL 120 Score = 35.0 bits (79), Expect = 0.15 Identities = 18/57 (31%), Positives = 33/57 (57%) Frame = +1 Query: 22 VVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQL 192 +V LD+ NQ+ LP+ G L L+ L++ N + +LP + + ++L+ L+ N L Sbjct: 64 IVRLDLSKNQIAQLPSEFGRLVNLQHLDLLQNRIVALPVSFAQLKSLKWLDLKDNPL 120
>LRC59_XENLA (Q8AVS8) Leucine-rich repeat-containing protein 59| Length = 307 Score = 43.5 bits (101), Expect = 4e-04 Identities = 30/103 (29%), Positives = 53/103 (51%), Gaps = 1/103 (0%) Frame = +1 Query: 31 LDVRSNQLKSLP-NSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPD 207 LD+ + L +P + + K L++S N L +LP + L+ + NQ+ +LP Sbjct: 20 LDLSLSDLSEVPVRDLVAIPKATALDLSCNKLTTLPDDFCNLSHIVRLDLSKNQIVQLPS 79 Query: 208 TLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIR 336 G L +L+ L + N L SLP S + + +L+ LD + N ++ Sbjct: 80 EFG-RLMNLQHLDLLQNHLMSLPVSFAQLKSLKWLDLKDNPLK 121 Score = 38.5 bits (88), Expect = 0.014 Identities = 21/60 (35%), Positives = 35/60 (58%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQL 192 L ++V LD+ NQ+ LP+ G L L+ L++ N L SLP + + ++L+ L+ N L Sbjct: 61 LSHIVRLDLSKNQIVQLPSEFGRLMNLQHLDLLQNHLMSLPVSFAQLKSLKWLDLKDNPL 120 Score = 29.3 bits (64), Expect = 8.3 Identities = 16/39 (41%), Positives = 23/39 (58%) Frame = +1 Query: 10 RLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQ 126 RL+N+ LD+ N L SLP S L L+ L++ N L+ Sbjct: 83 RLMNLQHLDLLQNHLMSLPVSFAQLKSLKWLDLKDNPLK 121
>TLR1_HUMAN (Q15399) Toll-like receptor 1 precursor (Toll/interleukin-1| receptor-like protein) (TIL) (CD281 antigen) Length = 786 Score = 43.5 bits (101), Expect = 4e-04 Identities = 27/83 (32%), Positives = 43/83 (51%), Gaps = 2/83 (2%) Frame = +1 Query: 88 KLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDTLGFELHSLRRLSVNSNKLT 267 +++VL++ N ++S+P + + AL+ELN FN LT LP F S+ + NS Sbjct: 446 RIKVLDLHSNKIKSIPKQVVKLEALQELNVAFNSLTDLPGCGSFSSLSVLIIDHNSVSHP 505 Query: 268 SLPF--STSHMTALRALDARLNC 330 S F S M +++A D C Sbjct: 506 SADFFQSCQKMRSIKAGDNPFQC 528 Score = 35.4 bits (80), Expect = 0.12 Identities = 17/38 (44%), Positives = 25/38 (65%) Frame = +1 Query: 22 VVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLP 135 + VLD+ SN++KS+P + L L+ LNV+ N L LP Sbjct: 447 IKVLDLHSNKIKSIPKQVVKLEALQELNVAFNSLTDLP 484 Score = 32.3 bits (72), Expect = 0.98 Identities = 50/188 (26%), Positives = 78/188 (41%), Gaps = 8/188 (4%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSLPNSIGC---LSKLRVLNVSGNLLQSLPATIEEC---RALEELN 174 L + L ++ NQLK L + L+ L++S N + S +C ++L LN Sbjct: 371 LTELETLILQMNQLKELSKIAEMTTQMKSLQQLDISQNSV-SYDEKKGDCSWTKSLLSLN 429 Query: 175 ANFNQLTRLPDTLGFELHS-LRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXX 351 + N LT DT+ L ++ L ++SNK+ S+P + AL+ L+ Sbjct: 430 MSSNILT---DTIFRCLPPRIKVLDLHSNKIKSIPKQVVKLEALQELNVA---------- 476 Query: 352 XXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSIS-VLPDSMGCLAKLNKFS 528 F+ L +LP G G +SL L I +NS+S D K+ Sbjct: 477 ---------------FNSLTDLP-GCGSFSSLSVLIIDHNSVSHPSADFFQSCQKMRSIK 520 Query: 529 AVGNPLIC 552 A NP C Sbjct: 521 AGDNPFQC 528 Score = 30.4 bits (67), Expect = 3.7 Identities = 25/85 (29%), Positives = 46/85 (54%), Gaps = 2/85 (2%) Frame = +1 Query: 28 VLDVRSNQLKSLPNS-IGCLSKLRVLNVSGNLLQSLPATIEEC-RALEELNANFNQLTRL 201 +L++ N + L S I LSKLR+L +S N +Q L ++ + + LE L+ + N+L ++ Sbjct: 49 ILNISQNYISELWTSDILSLSKLRILIISHNRIQYLDISVFKFNQELEYLDLSHNKLVKI 108 Query: 202 PDTLGFELHSLRRLSVNSNKLTSLP 276 +L+ L ++ N +LP Sbjct: 109 S---CHPTVNLKHLDLSFNAFDALP 130
>LRC15_RAT (Q8R5M3) Leucine-rich repeat-containing protein 15 precursor (rLib)| Length = 578 Score = 43.1 bits (100), Expect = 6e-04 Identities = 29/105 (27%), Positives = 53/105 (50%), Gaps = 3/105 (2%) Frame = +1 Query: 22 VVVLDVRSNQLKSL-PNSIGCLSKLRVLNVSGNLLQSLPATI-EECRALEELNANFNQLT 195 ++ L + N+L ++ P + L LR L+++ N L+ LP + ++ LE L + NQL Sbjct: 79 LIALKMEKNELSTIMPGAFRNLGSLRYLSLANNKLRMLPIRVFQDVNNLESLLLSNNQLV 138 Query: 196 RLPDTLGFELHSLRRLSVNSNKLTSLPFST-SHMTALRALDARLN 327 ++ + +LR L ++ N L S+P H+ L L+ N Sbjct: 139 QIQPAQFSQFSNLRELQLHGNNLESIPEEAFDHLVGLTKLNLGRN 183 Score = 38.5 bits (88), Expect = 0.014 Identities = 26/92 (28%), Positives = 49/92 (53%), Gaps = 2/92 (2%) Frame = +1 Query: 7 ARLLNVVVLDVRSNQLKSL-PNSIGCLSKLRVLNVSGNLLQSLPATIEECRA-LEELNAN 180 + L + VL + NQL + P + L+ LR L++ N LQ L + + A L+ ++ Sbjct: 314 SHLNQLQVLILSHNQLTYISPGAFNGLTNLRELSLHTNALQDLDSNVFRSLANLQNISLQ 373 Query: 181 FNQLTRLPDTLGFELHSLRRLSVNSNKLTSLP 276 N+L +LP ++ ++ L + + +N L +LP Sbjct: 374 SNRLRQLPGSIFANVNGLTTIQLQNNNLENLP 405
>TLR2_CRIGR (Q9R1F8) Toll-like receptor 2 precursor (CD282 antigen)| Length = 784 Score = 43.1 bits (100), Expect = 6e-04 Identities = 34/107 (31%), Positives = 52/107 (48%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQL 192 L N+ LD+ N +S+P+S K+R LN+S +Q++ I + LE L+ + N L Sbjct: 412 LKNLTALDISRNSFQSMPDSCQWPGKMRFLNLSSTGIQAVKMCIPQ--TLEVLDVSNNNL 469 Query: 193 TRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCI 333 + L LR L ++ NKL +LP S L + R N I Sbjct: 470 I----SFSLFLPLLRELYISRNKLHTLP-DASLFPVLLVMKIRENAI 511
>LRC59_BRARE (Q6NWG1) Leucine-rich repeat-containing protein 59| Length = 314 Score = 43.1 bits (100), Expect = 6e-04 Identities = 31/100 (31%), Positives = 52/100 (52%), Gaps = 1/100 (1%) Frame = +1 Query: 31 LDVRSNQLKSLP-NSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPD 207 LD+ + L +P + K L++S N L +L L +++ N NQL LP+ Sbjct: 18 LDLSLSNLTEVPVKELAAFPKATFLDLSCNNLITLTPEFCSLTHLIKIDLNKNQLVCLPE 77 Query: 208 TLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLN 327 +G +L +L+ L + +NKL LP S + +L+ LD + N Sbjct: 78 EIG-QLVNLQHLDLYNNKLKMLPIGFSQLKSLKWLDLKDN 116
>ALS_RAT (P35859) Insulin-like growth factor-binding protein complex acid| labile chain precursor (ALS) Length = 603 Score = 43.1 bits (100), Expect = 6e-04 Identities = 46/163 (28%), Positives = 72/163 (44%), Gaps = 5/163 (3%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSLPNSIGCLS---KLRVLNVSGNLLQSLPATI-EECRALEELNAN 180 L N+ L + N+L++L ++G + L L++S NLL L + + L +LN Sbjct: 121 LQNLYYLHLERNRLRNL--AVGLFTHTPSLASLSLSSNLLGRLEEGLFQGLSHLWDLNLG 178 Query: 181 FNQLTRLPDTLGFELHSLRRLSVNSNKLTSL-PFSTSHMTALRALDARLNCIRAXXXXXX 357 +N L LPDT+ L +L L + NKLT L P + LR LD N +R+ Sbjct: 179 WNSLVVLPDTVFQGLGNLHELVLAGNKLTYLQPALFCGLGELRELDLSRNALRSVKANVF 238 Query: 358 XXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVL 486 P + +LR LD+S+N ++ L Sbjct: 239 VHLPRLQKLYLDRNLITAVAPGAFLGMKALRWLDLSHNRVAGL 281 Score = 37.7 bits (86), Expect = 0.023 Identities = 43/185 (23%), Positives = 81/185 (43%), Gaps = 4/185 (2%) Frame = +1 Query: 31 LDVRSNQLKSL-PNSIGCLSKLRVLNVSGNLLQSL-PATIEECRALEELNANFNQLTRLP 204 LD+ N++ L ++ L L VL ++ N + SL P T ++ LEEL N++ +L Sbjct: 271 LDLSHNRVAGLMEDTFPGLLGLHVLRLAHNAIASLRPRTFKDLHFLEELQLGHNRIRQLG 330 Query: 205 DTLGFELHSLRRLSVNSNKLTSLPFST-SHMTALRALDARLNCIRAXXXXXXXXXXXXXX 381 + L L L++N N++T + S + + ++ NC+R+ Sbjct: 331 ERTFEGLGQLEVLTLNDNQITEVRVGAFSGLFNVAVMNLSGNCLRSLPERVFQGLDKLHS 390 Query: 382 XXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPD-SMGCLAKLNKFSAVGNPLICPP 558 ++ + L+ LR L + NSIS + + S+ L++L + N L P Sbjct: 391 LHLEHSCLGHVRLHTFAGLSGLRRLFLRDNSISSIEEQSLAGLSELLELDLTTNRLTHLP 450 Query: 559 MDIVE 573 + + Sbjct: 451 RQLFQ 455 Score = 33.5 bits (75), Expect = 0.44 Identities = 46/172 (26%), Positives = 71/172 (41%), Gaps = 4/172 (2%) Frame = +1 Query: 43 SNQLKSLPNSIGCLSKLRVLNVSGNLLQSLP-ATIEECRALEELNANFNQLTRLPDTLGF 219 S L LP+ I + R L + GN L S+P A + +L+ LN + L L Sbjct: 62 SKNLTHLPDDIPVST--RALWLDGNNLSSIPSAAFQNLSSLDFLNLQGSWLRSLEPQALL 119 Query: 220 ELHSLRRLSVNSNKLTSLPFST-SHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQN 396 L +L L + N+L +L +H +L +L N Sbjct: 120 GLQNLYYLHLERNRLRNLAVGLFTHTPSLASLSLSSN----------------------- 156 Query: 397 FHFLRELPYGLGL-LTSLRELDISYNSISVLPDSM-GCLAKLNKFSAVGNPL 546 L L GL L+ L +L++ +NS+ VLPD++ L L++ GN L Sbjct: 157 --LLGRLEEGLFQGLSHLWDLNLGWNSLVVLPDTVFQGLGNLHELVLAGNKL 206
>OMGP_HUMAN (P23515) Oligodendrocyte-myelin glycoprotein precursor| Length = 440 Score = 42.7 bits (99), Expect = 7e-04 Identities = 44/179 (24%), Positives = 76/179 (42%), Gaps = 1/179 (0%) Frame = +1 Query: 19 NVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTR 198 N++ L++ N L N + + LR L++S N L+SLPA + R+L ++A N + Sbjct: 56 NIIHLNLSYNHFTDLHNQLTQYTNLRTLDISNNRLESLPAHLP--RSLWNMSAANNNIKL 113 Query: 199 LPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXX 378 L + +L+ L V+ N L + + + +L L+ N + Sbjct: 114 LDKSDTAYQWNLKYLDVSKNMLEKVVLIKNTLRSLEVLNLSSNKL---WTVPTNMPSKLH 170 Query: 379 XXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPD-SMGCLAKLNKFSAVGNPLIC 552 N + LP L LT+L L + N + +PD S L +L + + N C Sbjct: 171 IVDLSNNSLTQILPGTLINLTNLTHLYLHNNKFTFIPDQSFDQLFQLQEITLYNNRWSC 229 Score = 41.2 bits (95), Expect = 0.002 Identities = 36/126 (28%), Positives = 62/126 (49%), Gaps = 23/126 (18%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLP--------------NSIGCLSK--------LRVLNVSGN 117 + + N+ LD+ +N+L+SLP N+I L K L+ L+VS N Sbjct: 74 LTQYTNLRTLDISNNRLESLPAHLPRSLWNMSAANNNIKLLDKSDTAYQWNLKYLDVSKN 133 Query: 118 LLQSLPATIEECRALEELNANFNQLTRLPDTLGFELHSLRRLSVNSNKLTS-LPFSTSHM 294 +L+ + R+LE LN + N+L +P + +LH + +++N LT LP + ++ Sbjct: 134 MLEKVVLIKNTLRSLEVLNLSSNKLWTVPTNMPSKLHI---VDLSNNSLTQILPGTLINL 190 Query: 295 TALRAL 312 T L L Sbjct: 191 TNLTHL 196
>LGR5_MOUSE (Q9Z1P4) Leucine-rich repeat-containing G-protein coupled receptor| 5 precursor (G-protein coupled receptor 49) (Orphan G-protein coupled receptor FEX) Length = 907 Score = 42.7 bits (99), Expect = 7e-04 Identities = 33/110 (30%), Positives = 58/110 (52%), Gaps = 7/110 (6%) Frame = +1 Query: 10 RLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLP-ATIEECRALEELNANFN 186 +L N+ VLD+ N L+ LP+ GC KL+ +++ N + + +T ++ L LN +N Sbjct: 350 QLPNLQVLDLSYNLLEDLPSLSGC-QKLQKIDLRHNEIYEIKGSTFQQLFNLRSLNLAWN 408 Query: 187 QLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSH------MTALRALDA 318 ++ + L SL +L ++SN L+S P + H +T RAL + Sbjct: 409 KIAIIHPNAFSTLPSLIKLDLSSNLLSSFPVTGLHGLTHLKLTGNRALQS 458 Score = 41.6 bits (96), Expect = 0.002 Identities = 46/181 (25%), Positives = 73/181 (40%), Gaps = 3/181 (1%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSLPNS-IGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQ 189 L ++VVL + +N++ SL L L L+++ N L P I+ L+EL + N Sbjct: 209 LSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTAIKTLSNLKELGFHSNN 268 Query: 190 LTRLPDTLGFELHSLRRLSVNSNKLTSLPFST-SHMTALRALDARLNCIRAXXXXXXXXX 366 + +P+ SL + N + + S H+ LR L LN Sbjct: 269 IRSIPERAFVGNPSLITIHFYDNPIQFVGVSAFQHLPELRTLT--LNGASHITEFPHLTG 326 Query: 367 XXXXXXXSQNFHFLRELPYGL-GLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNP 543 + + LP + L +L+ LD+SYN + LP GC KL K N Sbjct: 327 TATLESLTLTGAKISSLPQAVCDQLPNLQVLDLSYNLLEDLPSLSGC-QKLQKIDLRHNE 385 Query: 544 L 546 + Sbjct: 386 I 386 Score = 36.6 bits (83), Expect = 0.052 Identities = 25/76 (32%), Positives = 40/76 (52%), Gaps = 1/76 (1%) Frame = +1 Query: 52 LKSLPNSIGCLSKLRVLNVSGNLLQSLPATI-EECRALEELNANFNQLTRLPDTLGFELH 228 L LP+++ + L++S N + LPA++ LEEL N LT +P LH Sbjct: 57 LSELPSNLSVFTSY--LDLSMNNISQLPASLLHRLCFLEELRLAGNALTHIPKGAFTGLH 114 Query: 229 SLRRLSVNSNKLTSLP 276 SL+ L + +N+L +P Sbjct: 115 SLKVLMLQNNQLRKVP 130
>TMM_ARATH (Q9SSD1) TOO MANY MOUTHS protein precursor (TMM)| Length = 496 Score = 42.7 bits (99), Expect = 7e-04 Identities = 40/112 (35%), Positives = 59/112 (52%), Gaps = 4/112 (3%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLK-SLPNSIGCLSKLRVLNVSGN-LLQSLPATIEECRALEELNA 177 + L N+ VLD+ N L S+P S S LR L++SGN L S+P + AL L+ Sbjct: 179 LGNLTNLKVLDLHKNHLNGSIPLSFNRFSGLRSLDLSGNRLTGSIPGFV--LPALSVLDL 236 Query: 178 NFNQLT-RLPDTLGFELHSLRRLSVNSNKLTS-LPFSTSHMTALRALDARLN 327 N N LT +P TL SL ++ ++ N++T +P S + + L LD N Sbjct: 237 NQNLLTGPVPPTL-TSCGSLIKIDLSRNRVTGPIPESINRLNQLVLLDLSYN 287 Score = 40.4 bits (93), Expect = 0.004 Identities = 45/167 (26%), Positives = 71/167 (42%), Gaps = 4/167 (2%) Frame = +1 Query: 52 LKSLPNSIGCLSKLRVLNVSGNLLQ-SLPATIEECRALEELNANFNQLT-RLPDTLGFEL 225 L +P+ +G L+ L+VL++ N L S+P + L L+ + N+LT +P GF L Sbjct: 172 LGPIPDELGNLTNLKVLDLHKNHLNGSIPLSFNRFSGLRSLDLSGNRLTGSIP---GFVL 228 Query: 226 HSLRRLSVNSNKLTS-LPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFH 402 +L L +N N LT +P + + +L +D N + Sbjct: 229 PALSVLDLNQNLLTGPVPPTLTSCGSLIKIDLSRNRVTG--------------------- 267 Query: 403 FLRELPYGLGLLTSLRELDISYNSIS-VLPDSMGCLAKLNKFSAVGN 540 +P + L L LD+SYN +S P S+ L L GN Sbjct: 268 ---PIPESINRLNQLVLLDLSYNRLSGPFPSSLQGLNSLQALMLKGN 311 Score = 36.6 bits (83), Expect = 0.052 Identities = 22/63 (34%), Positives = 37/63 (58%), Gaps = 2/63 (3%) Frame = +1 Query: 13 LLNVVVLDVRSNQLK-SLPNSIGCLSKLRVLNVSG-NLLQSLPATIEECRALEELNANFN 186 L N+++L + + ++ S+P S+ L+ LRVL++ G NL +P + + L EL N N Sbjct: 326 LKNLMILVLSNTNIQGSIPKSLTRLNSLRVLHLEGNNLTGEIPLEFRDVKHLSELRLNDN 385 Query: 187 QLT 195 LT Sbjct: 386 SLT 388
>FLRT1_HUMAN (Q9NZU1) Leucine-rich repeat transmembrane protein FLRT1 precursor| (Fibronectin-like domain-containing leucine-rich transmembrane protein 1) Length = 646 Score = 42.4 bits (98), Expect = 0.001 Identities = 48/175 (27%), Positives = 81/175 (46%), Gaps = 7/175 (4%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSLPNSIGCLSK-LRVLNVSGNLLQSLPATIEECRALEELNANFNQ 189 LL + LD S S+ SK L++L +S N L S+P+ + LEEL + N+ Sbjct: 124 LLEKLHLDDNSVSTVSIEEDAFADSKQLKLLFLSRNHLSSIPSGLPH--TLEELRLDDNR 181 Query: 190 LTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIR-AXXXXXXXXX 366 ++ +P L+SLRRL ++ N L + + + L+ L L+ +R + Sbjct: 182 ISTIPLHAFKGLNSLRRLVLDGNLLANQRIADDTFSRLQNL-TELSLVRNSLAAPPLNLP 240 Query: 367 XXXXXXXSQNFHFLRELPYG-LGLLTSLRELDISYNSISVLP----DSMGCLAKL 516 + + +PY L + L LD+S N+++ LP D +G LA+L Sbjct: 241 SAHLQKLYLQDNAISHIPYNTLAKMRELERLDLSNNNLTTLPRGLFDDLGNLAQL 295
>SLIK2_MOUSE (Q810C0) SLIT and NTRK-like protein 2 precursor| Length = 846 Score = 42.4 bits (98), Expect = 0.001 Identities = 32/108 (29%), Positives = 55/108 (50%), Gaps = 2/108 (1%) Frame = +1 Query: 19 NVVVLDVRSNQLKSL-PNSIGCLSKLRVLNVSGNLLQSLPA-TIEECRALEELNANFNQL 192 N V L + +N L+ + P + L L+ L+++ N L+ L T +LE L A++N + Sbjct: 87 NAVTLHLGNNGLQEIRPGAFSGLKTLKRLHLNNNKLEVLREDTFLGLESLEYLQADYNYI 146 Query: 193 TRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIR 336 + + +L+ L+ L +N N L SLP + L LD R N ++ Sbjct: 147 STIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVLLTHLDLRGNRLK 194 Score = 37.0 bits (84), Expect = 0.040 Identities = 27/83 (32%), Positives = 45/83 (54%), Gaps = 1/83 (1%) Frame = +1 Query: 82 LSKLRVLNVSGNLLQSL-PATIEECRALEELNANFNQLTRLPDTLGFELHSLRRLSVNSN 258 L+ LR L ++GN L+ L P+ + ++L+ L +N + + L +L+ L +N+N Sbjct: 423 LTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNN 482 Query: 259 KLTSLPFSTSHMTALRALDARLN 327 L SLP + TAL L+ R N Sbjct: 483 LLRSLPDNIFGGTALTRLNLRNN 505 Score = 33.5 bits (75), Expect = 0.44 Identities = 43/156 (27%), Positives = 67/156 (42%), Gaps = 5/156 (3%) Frame = +1 Query: 100 LNVSGNLLQSLPAT-IEECRALEELNANFNQLTRLPDTLGFELHSLRRLSVNSNKLTSL- 273 L ++GN LQ++ + E +L+ L+ N++ + + L SLRRL +N N L L Sbjct: 381 LYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVLY 440 Query: 274 PFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRE 453 P + +L+ L N I+ N + LR LP + T+L Sbjct: 441 PSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNN-NLLRSLPDNIFGGTALTR 499 Query: 454 LDISYNSISVLPDSMGCLAKLNKFSAVG---NPLIC 552 L++ N S LP G L +L F + NP C Sbjct: 500 LNLRNNHFSHLP-VKGVLDQLPAFIQIDLQENPWDC 534 Score = 32.0 bits (71), Expect = 1.3 Identities = 22/65 (33%), Positives = 34/65 (52%), Gaps = 1/65 (1%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSL-PNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQ 189 L ++ L + N +K + P + L L++L ++ NLL+SLP I AL LN N Sbjct: 447 LQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIFGGTALTRLNLRNNH 506 Query: 190 LTRLP 204 + LP Sbjct: 507 FSHLP 511 Score = 29.3 bits (64), Expect = 8.3 Identities = 16/41 (39%), Positives = 25/41 (60%) Frame = +1 Query: 82 LSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLP 204 L+KL+VL ++ NLL SLP+ + L L+ N+L +P Sbjct: 157 LNKLKVLILNDNLLLSLPSNVFRFVLLTHLDLRGNRLKVMP 197
>TLR7_MOUSE (P58681) Toll-like receptor 7 precursor| Length = 1050 Score = 42.0 bits (97), Expect = 0.001 Identities = 36/112 (32%), Positives = 57/112 (50%), Gaps = 4/112 (3%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSLPNSI--GCLSKLRVLNVSGNLLQS-LPATIEECRALEELNANF 183 L N+ VLD+ N L SLP + G L+ L+++ N L+S ++ + LE L+ + Sbjct: 650 LFNLEVLDISRNSLNSLPPEVFEGMPPNLKNLSLAKNGLKSFFWDRLQLLKHLEILDLSH 709 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTSL-PFSTSHMTALRALDARLNCIR 336 NQLT++P+ L SL L + N++ L + LR LD N I+ Sbjct: 710 NQLTKVPERLANCSKSLTTLILKHNQIRQLTKYFLEDALQLRYLDISSNKIQ 761 Score = 31.6 bits (70), Expect = 1.7 Identities = 33/98 (33%), Positives = 47/98 (47%), Gaps = 6/98 (6%) Frame = +1 Query: 40 RSNQLKSLPNSIGCLSKLRVLNVSGNLL-QSLPAT-IEECRALEELNANFNQLTRLPDTL 213 R+N P+ LS L+ LN+SGN + Q+L + + R L L+ + N+L L T Sbjct: 503 RNNIFFIKPSDFQHLSFLKCLNLSGNTIGQTLNGSELWPLRELRYLDFSNNRLDLLYSTA 562 Query: 214 GFELHSLRRLSVNSNKLTSLPFSTSHM----TALRALD 315 EL SL L ++SN +HM LR LD Sbjct: 563 FEELQSLEVLDLSSNSHYFQAEGITHMLNFTKKLRLLD 600
>LRIG3_HUMAN (Q6UXM1) Leucine-rich repeats and immunoglobulin-like domains| protein 3 precursor (LIG-3) Length = 1119 Score = 42.0 bits (97), Expect = 0.001 Identities = 24/91 (26%), Positives = 57/91 (62%), Gaps = 1/91 (1%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGN-LLQSLPATIEECRALEELNAN 180 ++ L ++ + + +N+L+++PN + + +L+++GN +++ LP ++E ++LE L+ + Sbjct: 94 MSHLQSLREVKLNNNELETIPNLGPVSANITLLSLAGNRIVEILPEHLKEFQSLETLDLS 153 Query: 181 FNQLTRLPDTLGFELHSLRRLSVNSNKLTSL 273 N ++ L F L+ L +NSN++TS+ Sbjct: 154 SNNISEL--QTAFPALQLKYLYLNSNRVTSM 182 Score = 35.0 bits (79), Expect = 0.15 Identities = 36/160 (22%), Positives = 69/160 (43%), Gaps = 2/160 (1%) Frame = +1 Query: 22 VVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPA-TIEECRALEELNANFNQLTR 198 ++VL + N++ ++P + L +L+ L ++ N ++++ T + AL+ L N +T+ Sbjct: 194 LLVLKLNRNRISAIPPKMFKLPQLQHLELNRNKIKNVDGLTFQGLGALKSLKMQRNGVTK 253 Query: 199 LPDTLGFELHSLRRLSVNSNKLTSLPFSTSH-MTALRALDARLNCIRAXXXXXXXXXXXX 375 L D + L ++ L ++ N LT + + + L+ L N I Sbjct: 254 LMDGAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAIN------------- 300 Query: 376 XXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDS 495 R P L ELD+++N +S L DS Sbjct: 301 -----------RISPDAWEFCQKLSELDLTFNHLSRLDDS 329
>TLR6_MOUSE (Q9EPW9) Toll-like receptor 6 precursor| Length = 795 Score = 42.0 bits (97), Expect = 0.001 Identities = 34/104 (32%), Positives = 53/104 (50%), Gaps = 1/104 (0%) Frame = +1 Query: 19 NVVVLDVRSNQLKSLPNSIGCLS-KLRVLNVSGNLLQSLPATIEECRALEELNANFNQLT 195 +++VL++ SN L + CL K++VL++ N + S+P + +AL+ELN N LT Sbjct: 429 SILVLNLSSNMLTG--SVFRCLPPKVKVLDLHNNRIMSIPKDVTHLQALQELNVASNSLT 486 Query: 196 RLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLN 327 LP F S+ + NS S F S +R+L A N Sbjct: 487 DLPGCGAFSSLSVLVIDHNSVSHPSEDFFQSCQN-IRSLTAGNN 529
>LRTM1_PONPY (Q5R6B1) Leucine-rich repeat transmembrane neuronal protein 1| precursor Length = 522 Score = 41.6 bits (96), Expect = 0.002 Identities = 32/106 (30%), Positives = 55/106 (51%), Gaps = 3/106 (2%) Frame = +1 Query: 19 NVVVLDVRSNQLKSL-PNSIGCLSKLRVLNVSGNLLQSLPATI-EECRALEELNANFNQL 192 N+ +D+ N+L++L P+ L KL L++ N +Q +P I ++CR+L+ L+ +NQL Sbjct: 138 NLRSVDLSYNKLQALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQDCRSLKFLDIGYNQL 197 Query: 193 TRLPDTLGFELHSLRRLSVNSNKLTSLPFS-TSHMTALRALDARLN 327 L L L L + N L + F+ + +L +L R N Sbjct: 198 KSLARNSFAGLFKLTELHLEHNDLVKVNFAHFPRLISLHSLCLRRN 243 Score = 37.4 bits (85), Expect = 0.031 Identities = 29/90 (32%), Positives = 46/90 (51%), Gaps = 2/90 (2%) Frame = +1 Query: 10 RLLNVVVLDVRSNQLKSLPN-SIGCLSKLRVLNVSGNLLQSL-PATIEECRALEELNANF 183 +L V L + SNQ+ LPN + + LR +++S N LQ+L P R L L+ Sbjct: 111 KLRRVKELTLSSNQITQLPNTTFRPMPNLRSVDLSYNKLQALAPDLFHGLRKLTTLHMRA 170 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTSL 273 N + +P + + SL+ L + N+L SL Sbjct: 171 NAIQFVPVRIFQDCRSLKFLDIGYNQLKSL 200 Score = 37.0 bits (84), Expect = 0.040 Identities = 32/111 (28%), Positives = 55/111 (49%), Gaps = 3/111 (2%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSL-PNSIGCLSKLRVLNVSGNLLQSLPA-TIEECRALEELNANFN 186 L ++ L +R N L L L +L L + N + S+ ++ R ++EL + N Sbjct: 64 LSGLLGLSLRYNSLSELRAGQFTGLMQLTWLYLDHNHICSVQGDAFQKLRRVKELTLSSN 123 Query: 187 QLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSH-MTALRALDARLNCIR 336 Q+T+LP+T + +LR + ++ NKL +L H + L L R N I+ Sbjct: 124 QITQLPNTTFRPMPNLRSVDLSYNKLQALAPDLFHGLRKLTTLHMRANAIQ 174
>LRTM1_HUMAN (Q86UE6) Leucine-rich repeat transmembrane neuronal protein 1| precursor Length = 522 Score = 41.6 bits (96), Expect = 0.002 Identities = 32/106 (30%), Positives = 55/106 (51%), Gaps = 3/106 (2%) Frame = +1 Query: 19 NVVVLDVRSNQLKSL-PNSIGCLSKLRVLNVSGNLLQSLPATI-EECRALEELNANFNQL 192 N+ +D+ N+L++L P+ L KL L++ N +Q +P I ++CR+L+ L+ +NQL Sbjct: 138 NLRSVDLSYNKLQALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQDCRSLKFLDIGYNQL 197 Query: 193 TRLPDTLGFELHSLRRLSVNSNKLTSLPFS-TSHMTALRALDARLN 327 L L L L + N L + F+ + +L +L R N Sbjct: 198 KSLARNSFAGLFKLTELHLEHNDLVKVNFAHFPRLISLHSLCLRRN 243 Score = 37.4 bits (85), Expect = 0.031 Identities = 29/90 (32%), Positives = 46/90 (51%), Gaps = 2/90 (2%) Frame = +1 Query: 10 RLLNVVVLDVRSNQLKSLPN-SIGCLSKLRVLNVSGNLLQSL-PATIEECRALEELNANF 183 +L V L + SNQ+ LPN + + LR +++S N LQ+L P R L L+ Sbjct: 111 KLRRVKELTLSSNQITQLPNTTFRPMPNLRSVDLSYNKLQALAPDLFHGLRKLTTLHMRA 170 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTSL 273 N + +P + + SL+ L + N+L SL Sbjct: 171 NAIQFVPVRIFQDCRSLKFLDIGYNQLKSL 200 Score = 37.0 bits (84), Expect = 0.040 Identities = 32/111 (28%), Positives = 55/111 (49%), Gaps = 3/111 (2%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSL-PNSIGCLSKLRVLNVSGNLLQSLPA-TIEECRALEELNANFN 186 L ++ L +R N L L L +L L + N + S+ ++ R ++EL + N Sbjct: 64 LSGLLGLSLRYNSLSELRAGQFTGLMQLTWLYLDHNHICSVQGDAFQKLRRVKELTLSSN 123 Query: 187 QLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSH-MTALRALDARLNCIR 336 Q+T+LP+T + +LR + ++ NKL +L H + L L R N I+ Sbjct: 124 QITQLPNTTFRPMPNLRSVDLSYNKLQALAPDLFHGLRKLTTLHMRANAIQ 174
>IPA7_SHIFL (P18014) 60 kDa antigen| Length = 532 Score = 41.6 bits (96), Expect = 0.002 Identities = 53/197 (26%), Positives = 75/197 (38%), Gaps = 24/197 (12%) Frame = +1 Query: 28 VLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPD 207 VL++ L SLP +S L V N L LPA L+ELNA+ N+L+ +P+ Sbjct: 28 VLNLSDLNLTSLPELPKHISALIVENNKLTSLPKLPAF------LKELNADNNRLSVIPE 81 Query: 208 ------TLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXX 369 TL + L L V N LTSL + + L AL +L + Sbjct: 82 LPESLTTLSVRSNQLENLPVLPNHLTSLFVENNRLYNLPALPEKLKFLHVYYNRLTT--- 138 Query: 370 XXXXXXSQNFHFLRELPYGLGLLTSLR------------------ELDISYNSISVLPDS 495 L +LP L +L + R E +N I+ LP+S Sbjct: 139 ------------LPDLPDKLEILCAQRNNLVTFPQFSDRNNIRQKEYYFHFNQITTLPES 186 Query: 496 MGCLAKLNKFSAVGNPL 546 L + + GNPL Sbjct: 187 FSQLDSSYRINISGNPL 203 Score = 38.1 bits (87), Expect = 0.018 Identities = 32/86 (37%), Positives = 44/86 (51%) Frame = +1 Query: 19 NVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTR 198 ++ L VRSNQL++LP L+ L V N N L +LPA E+ L+ L+ +N+LT Sbjct: 85 SLTTLSVRSNQLENLPVLPNHLTSLFVEN---NRLYNLPALPEK---LKFLHVYYNRLTT 138 Query: 199 LPDTLGFELHSLRRLSVNSNKLTSLP 276 LPD L L N L + P Sbjct: 139 LPDL----PDKLEILCAQRNNLVTFP 160
>LGR6_HUMAN (Q9HBX8) Leucine-rich repeat-containing G-protein coupled receptor| 6 (VTS20631) Length = 828 Score = 41.2 bits (95), Expect = 0.002 Identities = 25/86 (29%), Positives = 47/86 (54%), Gaps = 1/86 (1%) Frame = +1 Query: 28 VLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPA-TIEECRALEELNANFNQLTRLP 204 VL++ NQ++ LP+ C KL + + N + + A T + +L+ L+ ++N + + Sbjct: 217 VLELSHNQIEELPSLHRC-QKLEEIGLQHNRIWEIGADTFSQLSSLQALDLSWNAIRSIH 275 Query: 205 DTLGFELHSLRRLSVNSNKLTSLPFS 282 LHSL +L + N+LT+LP + Sbjct: 276 PEAFSTLHSLVKLDLTDNQLTTLPLA 301 Score = 39.3 bits (90), Expect = 0.008 Identities = 24/73 (32%), Positives = 41/73 (56%), Gaps = 3/73 (4%) Frame = +1 Query: 82 LSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDTLGFELHSLRRLSVNSNK 261 L +LRVL +S N ++ LP ++ C+ LEE+ N++ + +L SL+ L ++ N Sbjct: 212 LPRLRVLELSHNQIEELP-SLHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLSWNA 270 Query: 262 LTSL---PFSTSH 291 + S+ FST H Sbjct: 271 IRSIHPEAFSTLH 283 Score = 39.3 bits (90), Expect = 0.008 Identities = 34/104 (32%), Positives = 47/104 (45%), Gaps = 2/104 (1%) Frame = +1 Query: 34 DVRSNQLKSL-PNSIGCLSKLRVLNVSGNLLQSLPA-TIEECRALEELNANFNQLTRLPD 207 D+ N L L P L L L +SGN L +P +L+ L NQL +P Sbjct: 29 DLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPA 88 Query: 208 TLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRA 339 +EL SL+ L +N NKL P + + L+ L N I+A Sbjct: 89 EALWELPSLQSLDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKA 132
>CT075_HUMAN (Q8WUT4) Protein C20orf75 precursor| Length = 740 Score = 41.2 bits (95), Expect = 0.002 Identities = 35/102 (34%), Positives = 54/102 (52%), Gaps = 2/102 (1%) Frame = +1 Query: 31 LDVRSNQLKSLPNS-IGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPD 207 LD N L++L S +G L +L+VL + N + +L L L+ ++NQL LP Sbjct: 80 LDASHNLLRALSTSELGHLEQLQVLTLRHNRIAALRWGPGGPAGLHTLDLSYNQLAALPP 139 Query: 208 TLGFELHSLRRLSVNSNKLTSL-PFSTSHMTALRALDARLNC 330 G L SLR L++ N L +L P + + AL+ L+ L+C Sbjct: 140 CTGPALSSLRALALAGNPLRALQPRAFACFPALQLLN--LSC 179 Score = 39.7 bits (91), Expect = 0.006 Identities = 45/150 (30%), Positives = 60/150 (40%), Gaps = 2/150 (1%) Frame = +1 Query: 103 NVSGNLLQSLPATIEECRALEELNANFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFS 282 N + + + LPA + AL N N L RLP L +LR L + N L +L S Sbjct: 42 NATDSPCEGLPAA--DATALTLANRN---LERLPGCLP---RTLRSLDASHNLLRALSTS 93 Query: 283 T-SHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELD 459 H+ L+ L R N I A L +G G L LD Sbjct: 94 ELGHLEQLQVLTLRHNRIAA-------------------------LRWGPGGPAGLHTLD 128 Query: 460 ISYNSISVLPDSMG-CLAKLNKFSAVGNPL 546 +SYN ++ LP G L+ L + GNPL Sbjct: 129 LSYNQLAALPPCTGPALSSLRALALAGNPL 158
>LRC20_MOUSE (Q8CI70) Leucine-rich repeat-containing protein 20| Length = 184 Score = 41.2 bits (95), Expect = 0.002 Identities = 23/80 (28%), Positives = 40/80 (50%) Frame = +1 Query: 31 LDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDT 210 L + N L LPN + L LR +++S N Q P + ALE +N N++ +P Sbjct: 79 LRLEGNYLFRLPNEVSSLQHLRAIDLSRNQFQDFPEQLTTLPALETINLEENEIVDVPVE 138 Query: 211 LGFELHSLRRLSVNSNKLTS 270 + +LR +++ N L++ Sbjct: 139 KLAAMPALRVINLRLNPLSA 158
>OMGP_MOUSE (Q63912) Oligodendrocyte-myelin glycoprotein precursor| Length = 440 Score = 41.2 bits (95), Expect = 0.002 Identities = 43/179 (24%), Positives = 76/179 (42%), Gaps = 1/179 (0%) Frame = +1 Query: 19 NVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTR 198 N++ L++ N L N + + LR L++S N L+SLPA + R+L ++A N + Sbjct: 56 NIIHLNLSYNHFTDLHNQLTPYTNLRTLDISNNRLESLPAQLP--RSLWNMSAANNNIKL 113 Query: 199 LPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXX 378 L + +L+ L V+ N L + + + +L L+ N + Sbjct: 114 LDKSDTAYQWNLKYLDVSKNMLEKVVLIKNTLRSLEVLNLSSNKL---WTVPTNMPSKLH 170 Query: 379 XXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPD-SMGCLAKLNKFSAVGNPLIC 552 N + LP L LT+L L + N + +P+ S L +L + + N C Sbjct: 171 IVDLSNNSLTQILPGTLINLTNLTHLYLHNNKFTFIPEQSFDQLLQLQEITLHNNRWSC 229
>TLR9_FELCA (Q5I2M7) Toll-like receptor 9 precursor (CD289 antigen)| Length = 1031 Score = 41.2 bits (95), Expect = 0.002 Identities = 55/191 (28%), Positives = 80/191 (41%), Gaps = 10/191 (5%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPAT-------IEECRAL 162 +A+L + L + N + S + C + LR L+ SGN L + A R+L Sbjct: 571 VAQLPALRYLSLAHNDIHSRVSQQLCSASLRALDFSGNALSRMWAEGDLYLHFFRGLRSL 630 Query: 163 EELNANFNQL-TRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTA-LRALDARLNCIR 336 L+ + N+L T LP TL SLR L + N L +S+ + L ALD N ++ Sbjct: 631 VRLDLSQNRLHTLLPRTLDNLPKSLRLLRLRDNYLAFFNWSSLVLLPRLEALDLAGNQLK 690 Query: 337 AXXXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLA-K 513 A LP G T L+ LD+S NSIS + S LA + Sbjct: 691 ALSNGS--------------------LPNG----TQLQRLDLSSNSISFVASSFFALATR 726 Query: 514 LNKFSAVGNPL 546 L + + N L Sbjct: 727 LRELNLSANAL 737 Score = 37.7 bits (86), Expect = 0.023 Identities = 36/108 (33%), Positives = 49/108 (45%), Gaps = 9/108 (8%) Frame = +1 Query: 40 RSNQLKSLPNSIGCLSKLRVLNVSGNL---------LQSLPATIEECRALEELNANFNQL 192 R+N L P ++ L LR L + GN LQ P + L L+ +N L Sbjct: 152 RTNILVLDPANLAGLHSLRFLFLDGNCYYKNPCPQALQVAPGALLGLGNLTHLSLKYNNL 211 Query: 193 TRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIR 336 T +P L L L LS N + +T P +++TALR LD NC R Sbjct: 212 TAVPRGLPPSLEYLL-LSYN-HIITLAPEDLANLTALRVLDVGGNCRR 257 Score = 30.0 bits (66), Expect = 4.9 Identities = 27/97 (27%), Positives = 44/97 (45%), Gaps = 4/97 (4%) Frame = +1 Query: 241 LSVNSNKLTSLPFSTS-HMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHFLREL 417 LS+ SN++ L S H+++LR L+ + NC A HF + Sbjct: 68 LSLYSNRIHHLHDSDFVHLSSLRRLNLKWNCPPASLSP---------------MHFPCHM 112 Query: 418 ---PYGLGLLTSLRELDISYNSISVLPDSMGCLAKLN 519 P+ + +L EL++SYNSI+ +P L L+ Sbjct: 113 TIEPHTFLAVPTLEELNLSYNSITTVPALPSSLVSLS 149
>OMD_RAT (Q9Z1S7) Osteomodulin precursor (Osteoadherin) (OSAD) (Keratan| sulfate proteoglycan osteomodulin) (KSPG osteomodulin) Length = 423 Score = 41.2 bits (95), Expect = 0.002 Identities = 30/111 (27%), Positives = 55/111 (49%), Gaps = 3/111 (2%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSLP---NSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 L+NV +LD+ N L + L KL LN+ N L+S+P + +L L+ Sbjct: 185 LVNVTMLDLCYNHLSDSTLKGKILSKLEKLMQLNLCNNRLESMPPGLP--LSLMYLSLEN 242 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIR 336 N ++ +P+ +L L L ++ NKL +P+ +++ L L+ N ++ Sbjct: 243 NSISSIPEDYFQKLPKLHALRISHNKLEDIPYDIFNLSNLIELNVGHNKLK 293
>SLIT_DROME (P24014) Protein slit precursor [Contains: Protein slit N-product;| Protein slit C-product] Length = 1504 Score = 41.2 bits (95), Expect = 0.002 Identities = 32/112 (28%), Positives = 60/112 (53%), Gaps = 6/112 (5%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSLP-NSIGCLSKLRVLNVSGNLLQSLPATI-EECRALEELNANFN 186 L+++ L + +N+LK++P N + + L L++S N++ ++ + + ++L L + N Sbjct: 147 LVSLERLRLNNNRLKAIPENFVTSSASLLRLDISNNVITTVGRRVFKGAQSLRSLQLDNN 206 Query: 187 QLTRLPDTLGFELHSLRRLSVNSNKLTSLPFS----TSHMTALRALDARLNC 330 Q+T L + L L L++N+N LTSLP + + ALR D C Sbjct: 207 QITCLDEHAFKGLVELEILTLNNNNLTSLPHNIFGGLGRLRALRLSDNPFAC 258 Score = 38.1 bits (87), Expect = 0.018 Identities = 45/178 (25%), Positives = 70/178 (39%), Gaps = 4/178 (2%) Frame = +1 Query: 31 LDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPAT-IEECRALEELNANFNQLTRLPD 207 +D L S+P I + + L + GN L + T + L L NQ+ + Sbjct: 84 VDCSHRGLTSVPRKIS--ADVERLELQGNNLTVIYETDFQRLTKLRMLQLTDNQIHTIER 141 Query: 208 TLGFELHSLRRLSVNSNKLTSLP--FSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXX 381 +L SL RL +N+N+L ++P F TS + LR LD N I Sbjct: 142 NSFQDLVSLERLRLNNNRLKAIPENFVTSSASLLR-LDISNNVITTVGRRVFKGAQSLRS 200 Query: 382 XXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSM-GCLAKLNKFSAVGNPLIC 552 N + L L L ++ N+++ LP ++ G L +L NP C Sbjct: 201 LQLDNNQITCLDEHAFKGLVELEILTLNNNNLTSLPHNIFGGLGRLRALRLSDNPFAC 258 Score = 30.0 bits (66), Expect = 4.9 Identities = 30/97 (30%), Positives = 42/97 (43%), Gaps = 1/97 (1%) Frame = +1 Query: 46 NQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDTLGFEL 225 NQLK +P I + L S + Q I R+L L+ + NQ+T L + L Sbjct: 755 NQLKEIPRGIPAETSELYLE-SNEIEQIHYERIRHLRSLTRLDLSNNQITILSNYTFANL 813 Query: 226 HSLRRLSVNSNKLTSLP-FSTSHMTALRALDARLNCI 333 L L ++ NKL L + S + LR L N I Sbjct: 814 TKLSTLIISYNKLQCLQRHALSGLNNLRVLSLHGNRI 850
>LRTM1_MOUSE (Q8K377) Leucine-rich repeat transmembrane neuronal protein 1| precursor Length = 522 Score = 41.2 bits (95), Expect = 0.002 Identities = 32/106 (30%), Positives = 55/106 (51%), Gaps = 3/106 (2%) Frame = +1 Query: 19 NVVVLDVRSNQLKSL-PNSIGCLSKLRVLNVSGNLLQSLPATI-EECRALEELNANFNQL 192 N+ +D+ N+L++L P+ L KL L++ N +Q +P I ++CR+L+ L+ +NQL Sbjct: 138 NLRSVDLSYNKLQALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQDCRSLKFLDIGYNQL 197 Query: 193 TRLPDTLGFELHSLRRLSVNSNKLTSLPFS-TSHMTALRALDARLN 327 L L L L + N L + F+ + +L +L R N Sbjct: 198 KSLARNSFAGLFKLTELHLEHNDLIKVNFAHFPRLISLHSLCLRRN 243 Score = 33.5 bits (75), Expect = 0.44 Identities = 31/111 (27%), Positives = 53/111 (47%), Gaps = 3/111 (2%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSL-PNSIGCLSKLRVLNVSGNLLQSLPA-TIEECRALEELNANFN 186 L ++ L +R N L L L +L L + N + S+ ++ R ++EL + N Sbjct: 64 LSGLLGLSLRYNSLSELRAGQFTGLMQLTWLYLDHNHICSVQGDAFQKLRRVKELTLSSN 123 Query: 187 QLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSH-MTALRALDARLNCIR 336 Q+T L +T + +LR + ++ NKL +L H + L L R N I+ Sbjct: 124 QITELANTTFRPMPNLRSVDLSYNKLQALAPDLFHGLRKLTTLHMRANAIQ 174
>TLR1_MOUSE (Q9EPQ1) Toll-like receptor 1 precursor (Toll/interleukin-1| receptor-like protein) (TIL) (CD281 antigen) Length = 795 Score = 41.2 bits (95), Expect = 0.002 Identities = 34/104 (32%), Positives = 53/104 (50%), Gaps = 1/104 (0%) Frame = +1 Query: 19 NVVVLDVRSNQLKSLPNSIGCLS-KLRVLNVSGNLLQSLPATIEECRALEELNANFNQLT 195 +++VL++ SN L + CL K++VL++ N + S+P + +AL+ELN N LT Sbjct: 427 SLLVLNLSSNMLTG--SVFRCLPPKVKVLDLHNNRIMSIPKDVTHLQALQELNVASNSLT 484 Query: 196 RLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLN 327 LP F S+ + NS S F S +R+L A N Sbjct: 485 DLPGCGAFSSLSVLVIDHNSVSHPSEDFFQSCQN-IRSLTAGNN 527 Score = 34.3 bits (77), Expect = 0.26 Identities = 31/89 (34%), Positives = 45/89 (50%), Gaps = 2/89 (2%) Frame = +1 Query: 16 LNVVVLDVRSNQLKSLPNS-IGCLSKLRVLNVSGNLLQSLPATIEECRA-LEELNANFNQ 189 L LD+ N + L S I LSKLRVL +S N LQ L ++ + LE L+ + N+ Sbjct: 48 LQTTTLDLSQNNISELQTSDILSLSKLRVLIMSYNRLQYLNISVFKFNTELEYLDLSHNE 107 Query: 190 LTRLPDTLGFELHSLRRLSVNSNKLTSLP 276 L + L SL+ L ++ N +LP Sbjct: 108 LKVI---LCHPTVSLKHLDLSFNAFDALP 133
>LRC32_HUMAN (Q14392) Leucine-rich repeat-containing protein 32 precursor (GARP| protein) (Garpin) (Glycoprotein A repetitions predominant) Length = 662 Score = 41.2 bits (95), Expect = 0.002 Identities = 42/176 (23%), Positives = 71/176 (40%), Gaps = 4/176 (2%) Frame = +1 Query: 31 LDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLP-- 204 LD+R N+L P+ + L +L LN+S NL++ ++ + + + ++ L Sbjct: 248 LDLRENKLLHFPD-LAALPRLIYLNLSNNLIRLPTGPPQDSKGIHAPSEGWSALPLSAPS 306 Query: 205 -DTLGFELHSLRRLSVNSNKLTSLPFS-TSHMTALRALDARLNCIRAXXXXXXXXXXXXX 378 + G L L L ++ N++ +P S H+T+L L+ NC+R Sbjct: 307 GNASGRPLSQLLNLDLSYNEIELIPDSFLEHLTSLCFLNLSRNCLRTFEARR-------- 358 Query: 379 XXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPL 546 LG L L LD+S+N++ L L L GN L Sbjct: 359 ----------------LGSLPCLMLLDLSHNALETLELGARALGSLRTLLLQGNAL 398
>VASN_HUMAN (Q6EMK4) Vasorin precursor (Protein Slit-like 2)| Length = 673 Score = 40.8 bits (94), Expect = 0.003 Identities = 48/184 (26%), Positives = 77/184 (41%), Gaps = 3/184 (1%) Frame = +1 Query: 7 ARLLNVVVLDVRSNQLKSLPNSI-GCLSKLRVLNVSGNLLQSLP-ATIEECRALEELNAN 180 A L + +LD+ NQ+ SLP+ + L+ L L+++ N L + T R LE L Sbjct: 73 AGLPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEITNETFRGLRRLERLYLG 132 Query: 181 FNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXX 360 N++ + L L L + N+L +LP + L LD N + A Sbjct: 133 KNRIRHIQPGAFDTLDRLLELKLQDNELRALP--PLRLPRLLLLDLSHNSLLALEPGILD 190 Query: 361 XXXXXXXXXSQNFHFLRELPYGL-GLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVG 537 + L++L GL L +L +LD+S N + +P + L L + G Sbjct: 191 TANVEALRLAGLG--LQQLDEGLFSRLRNLHDLDVSDNQLERVPPVIRGLRGLTRLRLAG 248 Query: 538 NPLI 549 N I Sbjct: 249 NTRI 252 Score = 37.7 bits (86), Expect = 0.023 Identities = 30/86 (34%), Positives = 42/86 (48%), Gaps = 2/86 (2%) Frame = +1 Query: 7 ARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGN--LLQSLPATIEECRALEELNAN 180 +RL N+ LDV NQL+ +P I L L L ++GN + Q P + AL+EL+ + Sbjct: 213 SRLRNLHDLDVSDNQLERVPPVIRGLRGLTRLRLAGNTRIAQLRPEDLAGLAALQELDVS 272 Query: 181 FNQLTRLPDTLGFELHSLRRLSVNSN 258 L LP L LR L+ N Sbjct: 273 NLSLQALPGDLSGLFPRLRLLAAARN 298
>LRFN3_HUMAN (Q9BTN0) Leucine-rich repeat and fibronectin type-III| domain-containing protein 3 precursor Length = 628 Score = 40.4 bits (93), Expect = 0.004 Identities = 38/116 (32%), Positives = 57/116 (49%), Gaps = 27/116 (23%) Frame = +1 Query: 10 RLLNVVVLDVRSNQLKSL-PNSIGCLSKLRVLNVSGNLLQSLPA-TIEEC-RALEELNAN 180 R L + LD N+L SL + L LR L +S N L +L A +++C LE+L+ + Sbjct: 107 RALRALHLD--GNRLTSLGEGQLRGLVNLRHLILSNNQLAALAAGALDDCAETLEDLDLS 164 Query: 181 FNQLTRLP----------DTLGFE--------------LHSLRRLSVNSNKLTSLP 276 +N L +LP +TLG + LH L RL + SN+LT++P Sbjct: 165 YNNLEQLPWEALGRLGNVNTLGLDHNLLASVPAGAFSRLHKLARLDMTSNRLTTIP 220 Score = 34.7 bits (78), Expect = 0.20 Identities = 41/181 (22%), Positives = 74/181 (40%), Gaps = 3/181 (1%) Frame = +1 Query: 31 LDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDT 210 LD R+ +L+ N I + + + N++G L L+ + N + + Sbjct: 57 LDRRAAELRLADNFIASVRRRDLANMTGLL---------------HLSLSRNTIRHVAAG 101 Query: 211 LGFELHSLRRLSVNSNKLTSL-PFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXX 387 +L +LR L ++ N+LTSL + LR L N + A Sbjct: 102 AFADLRALRALHLDGNRLTSLGEGQLRGLVNLRHLILSNNQLAALAAGALDDCAETLEDL 161 Query: 388 SQNFHFLRELPY-GLGLLTSLRELDISYNSISVLP-DSMGCLAKLNKFSAVGNPLICPPM 561 +++ L +LP+ LG L ++ L + +N ++ +P + L KL + N L P Sbjct: 162 DLSYNNLEQLPWEALGRLGNVNTLGLDHNLLASVPAGAFSRLHKLARLDMTSNRLTTIPP 221 Query: 562 D 564 D Sbjct: 222 D 222
>BRL2_ARATH (Q9ZPS9) Serine/threonine-protein kinase BRI1-like 2 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 2) (Protein VASCULAR HIGHWAY 1) Length = 1143 Score = 40.4 bits (93), Expect = 0.004 Identities = 38/151 (25%), Positives = 73/151 (48%), Gaps = 4/151 (2%) Frame = +1 Query: 61 LPNSIGCLSKLRVLNVSGNLLQ-SLPATIEECRALEELNANFNQLT-RLPDTLGFELHSL 234 +P +I S+LR +++S N L ++P I + LE+ A +N + +P +G +L +L Sbjct: 391 IPPAISQCSELRTIDLSLNYLNGTIPPEIGNLQKLEQFIAWYNNIAGEIPPEIG-KLQNL 449 Query: 235 RRLSVNSNKLTS-LPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHFLR 411 + L +N+N+LT +P + + + + N + N +F Sbjct: 450 KDLILNNNQLTGEIPPEFFNCSNIEWVSFTSNRLTGEVPKDFGILSRLAVLQLGNNNFTG 509 Query: 412 ELPYGLGLLTSLRELDISYNSIS-VLPDSMG 501 E+P LG T+L LD++ N ++ +P +G Sbjct: 510 EIPPELGKCTTLVWLDLNTNHLTGEIPPRLG 540 Score = 34.7 bits (78), Expect = 0.20 Identities = 31/135 (22%), Positives = 61/135 (45%), Gaps = 2/135 (1%) Frame = +1 Query: 154 RALEELNANFNQLT-RLPDTLGFELHSLRRLSVNSNKLTS-LPFSTSHMTALRALDARLN 327 + +E L+ ++NQL ++PD +G E+ +L+ L ++ N+L+ +PF+ + L DA N Sbjct: 611 QTIEYLDLSYNQLRGKIPDEIG-EMIALQVLELSHNQLSGEIPFTIGQLKNLGVFDASDN 669 Query: 328 CIRAXXXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCL 507 ++ ++P L+ L ++D+S N ++ G L Sbjct: 670 RLQG------------------------QIPESFSNLSFLVQIDLSNNELTGPIPQRGQL 705 Query: 508 AKLNKFSAVGNPLIC 552 + L NP +C Sbjct: 706 STLPATQYANNPGLC 720 Score = 29.3 bits (64), Expect = 8.3 Identities = 29/130 (22%), Positives = 51/130 (39%), Gaps = 6/130 (4%) Frame = +1 Query: 109 SGNLLQSLPATI-EECRALEELNANFNQLT-RLPDTLGFELHSLRRLSVNSNKLTS---- 270 S L+ +LP + L + ++N T +LP+ L L+ L ++ N +T Sbjct: 136 SSGLIGTLPENFFSKYSNLISITLSYNNFTGKLPNDLFLSSKKLQTLDLSYNNITGPISG 195 Query: 271 LPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLR 450 L S ++ LD N I +F ++P G L L+ Sbjct: 196 LTIPLSSCVSMTYLDFSGNSISGYISDSLINCTNLKSLNLSYNNFDGQIPKSFGELKLLQ 255 Query: 451 ELDISYNSIS 480 LD+S+N ++ Sbjct: 256 SLDLSHNRLT 265
>LRFN5_MOUSE (Q8BXA0) Leucine-rich repeat and fibronectin type-III| domain-containing protein 5 precursor Length = 719 Score = 40.4 bits (93), Expect = 0.004 Identities = 36/116 (31%), Positives = 53/116 (45%), Gaps = 26/116 (22%) Frame = +1 Query: 7 ARLLNVVVLDVRSNQLKSLPNSI-GCLSKLRVLNVSGNLLQSLPAT-IEECRALEELNAN 180 A L N+ L + SN+L + N + LS L L ++ N L + +T ++ ALEEL+ + Sbjct: 96 ADLRNLRALHLNSNRLTKITNDMFSGLSNLHHLILNNNQLTLISSTAFDDVFALEELDLS 155 Query: 181 FNQLTRLP----------DTLGFE--------------LHSLRRLSVNSNKLTSLP 276 +N L +P TL + LH + RL V SNKL LP Sbjct: 156 YNNLETIPWDAVEKMVSLHTLSLDHNMIDNIPKGTFSHLHKMTRLDVTSNKLQKLP 211
>LRFN5_HUMAN (Q96NI6) Leucine-rich repeat and fibronectin type-III| domain-containing protein 5 precursor Length = 719 Score = 40.4 bits (93), Expect = 0.004 Identities = 36/116 (31%), Positives = 53/116 (45%), Gaps = 26/116 (22%) Frame = +1 Query: 7 ARLLNVVVLDVRSNQLKSLPNSI-GCLSKLRVLNVSGNLLQSLPAT-IEECRALEELNAN 180 A L N+ L + SN+L + N + LS L L ++ N L + +T ++ ALEEL+ + Sbjct: 96 ADLRNLRALHLNSNRLTKITNDMFSGLSNLHHLILNNNQLTLISSTAFDDVFALEELDLS 155 Query: 181 FNQLTRLP----------DTLGFE--------------LHSLRRLSVNSNKLTSLP 276 +N L +P TL + LH + RL V SNKL LP Sbjct: 156 YNNLETIPWDAVEKMVSLHTLSLDHNMIDNIPKGTFSHLHKMTRLDVTSNKLQKLP 211
>PSKR_DAUCA (Q8LPB4) Phytosulfokine receptor precursor (EC 2.7.11.1)| (Phytosulfokine LRR receptor kinase) Length = 1021 Score = 40.4 bits (93), Expect = 0.004 Identities = 49/181 (27%), Positives = 67/181 (37%), Gaps = 2/181 (1%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 + L N+ VLD+ SN L S+ L LRVLNV N L Sbjct: 130 LLNLSNLEVLDLSSNDFSGLFPSLINLPSLRVLNVYENSFHGL----------------- 172 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLT-SLPFSTSHMTALRALDARLNCIRAXXXXXXX 360 +P +L L +R + + N S+P + +++ L N + Sbjct: 173 -----IPASLCNNLPRIREIDLAMNYFDGSIPVGIGNCSSVEYLGLASNNLSGSIPQELF 227 Query: 361 XXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSIS-VLPDSMGCLAKLNKFSAVG 537 QN L LG L++L LDIS N S +PD L KL FSA Sbjct: 228 QLSNLSVLALQNNRLSGALSSKLGKLSNLGRLDISSNKFSGKIPDVFLELNKLWYFSAQS 287 Query: 538 N 540 N Sbjct: 288 N 288 Score = 37.4 bits (85), Expect = 0.031 Identities = 46/186 (24%), Positives = 78/186 (41%), Gaps = 10/186 (5%) Frame = +1 Query: 28 VLDVRSNQLK-SLPNSIGCLSKLRVLNVSGNL--------LQSLPATIEECRALEELNAN 180 +LD+ NQL ++P +G L+ L L++S N L SL + + + A+EE + Sbjct: 453 LLDLSWNQLSGTIPPWLGSLNSLFYLDLSNNTFIGEIPHSLTSLQSLVSKENAVEEPS-- 510 Query: 181 FNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXX 360 PD F+ + + N+ +S P +D N + Sbjct: 511 -------PDFPFFKKKNTNAGGLQYNQPSSFP---------PMIDLSYNSLNGSIWPEFG 554 Query: 361 XXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSIS-VLPDSMGCLAKLNKFSAVG 537 +N + +P L +TSL LD+S+N++S +P S+ L+ L+ FS Sbjct: 555 DLRQLHVLNLKNNNLSGNIPANLSGMTSLEVLDLSHNNLSGNIPPSLVKLSFLSTFSVAY 614 Query: 538 NPLICP 555 N L P Sbjct: 615 NKLSGP 620
>LRFN4_MOUSE (Q80XU8) Leucine-rich repeat and fibronectin type-III| domain-containing protein 4 precursor Length = 636 Score = 40.4 bits (93), Expect = 0.004 Identities = 37/146 (25%), Positives = 67/146 (45%), Gaps = 3/146 (2%) Frame = +1 Query: 100 LNVSGNLLQSL-PATIEECRALEELNANFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLP 276 L ++ N +Q+L P L +L + N +TR+ +L SLR L ++ N+L L Sbjct: 53 LRLADNFIQALGPPDFRNMTGLVDLTLSRNAITRIGARSFGDLESLRSLHLDGNRLVELG 112 Query: 277 FSTSH-MTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHFLRELPY-GLGLLTSLR 450 S+ L+ L N + +++ LR++P+ G+G + +L Sbjct: 113 SSSLRGPVNLQHLILSGNQLGRIAPGAFDDFLDSLEDLDVSYNNLRQVPWAGIGSMPALH 172 Query: 451 ELDISYNSISVLPDSMGCLAKLNKFS 528 L++ +N I LP G A+L++ S Sbjct: 173 TLNLDHNLIDALPP--GVFAQLSQLS 196 Score = 32.7 bits (73), Expect = 0.75 Identities = 23/64 (35%), Positives = 32/64 (50%), Gaps = 3/64 (4%) Frame = +1 Query: 31 LDVRSNQLKSLP-NSIGCLSKLRVLNVSGNLLQSL-PATIEECRALEELNANFNQLTRL- 201 LDV N L+ +P IG + L LN+ NL+ +L P + L L+ N+L L Sbjct: 150 LDVSYNNLRQVPWAGIGSMPALHTLNLDHNLIDALPPGVFAQLSQLSRLDLTSNRLATLA 209 Query: 202 PDTL 213 PD L Sbjct: 210 PDPL 213
>LRC59_CHICK (Q5F334) Leucine-rich repeat-containing protein 59| Length = 339 Score = 40.4 bits (93), Expect = 0.004 Identities = 25/67 (37%), Positives = 35/67 (52%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 +A L VLD+ N L SLP+ L+ L L++S N LQ LP +L+ L+ Sbjct: 35 LAALPKATVLDLSCNSLVSLPSDFCSLTHLVKLDLSKNRLQQLPVDFGRLVSLQHLDLLN 94 Query: 184 NQLTRLP 204 N+L LP Sbjct: 95 NRLVTLP 101 Score = 40.4 bits (93), Expect = 0.004 Identities = 30/89 (33%), Positives = 48/89 (53%), Gaps = 1/89 (1%) Frame = +1 Query: 31 LDVRSNQLKSLP-NSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPD 207 LD+ L +P + L K VL++S N L SLP+ L +L+ + N+L +LP Sbjct: 20 LDLSLCGLSEVPVRELAALPKATVLDLSCNSLVSLPSDFCSLTHLVKLDLSKNRLQQLPV 79 Query: 208 TLGFELHSLRRLSVNSNKLTSLPFSTSHM 294 G L SL+ L + +N+L +LP S + + Sbjct: 80 DFG-RLVSLQHLDLLNNRLVTLPVSFAQL 107
>LRFN3_MOUSE (Q8BLY3) Leucine-rich repeat and fibronectin type-III| domain-containing protein 3 precursor Length = 626 Score = 40.4 bits (93), Expect = 0.004 Identities = 38/116 (32%), Positives = 57/116 (49%), Gaps = 27/116 (23%) Frame = +1 Query: 10 RLLNVVVLDVRSNQLKSL-PNSIGCLSKLRVLNVSGNLLQSLPA-TIEEC-RALEELNAN 180 R L + LD N+L SL + L LR L +S N L +L A +++C LE+L+ + Sbjct: 107 RALRALHLD--GNRLTSLGEGQLRGLVNLRHLILSNNQLAALAAGALDDCAETLEDLDLS 164 Query: 181 FNQLTRLP----------DTLGFE--------------LHSLRRLSVNSNKLTSLP 276 +N L +LP +TLG + LH L RL + SN+LT++P Sbjct: 165 YNNLEQLPWEALGRLGNVNTLGLDHNLLASVPAGAFSRLHKLARLDMTSNRLTTIP 220 Score = 35.0 bits (79), Expect = 0.15 Identities = 41/181 (22%), Positives = 74/181 (40%), Gaps = 3/181 (1%) Frame = +1 Query: 31 LDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDT 210 LD R+ +L+ N I + + + N++G L L+ + N + + Sbjct: 57 LDRRAAELRLADNFIAAVRRRDLANMTGLL---------------HLSLSRNTIRHVAAG 101 Query: 211 LGFELHSLRRLSVNSNKLTSL-PFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXX 387 +L +LR L ++ N+LTSL + LR L N + A Sbjct: 102 AFADLRALRALHLDGNRLTSLGEGQLRGLVNLRHLILSNNQLAALAAGALDDCAETLEDL 161 Query: 388 SQNFHFLRELPY-GLGLLTSLRELDISYNSISVLP-DSMGCLAKLNKFSAVGNPLICPPM 561 +++ L +LP+ LG L ++ L + +N ++ +P + L KL + N L P Sbjct: 162 DLSYNNLEQLPWEALGRLGNVNTLGLDHNLLASVPAGAFSRLHKLARLDMTSNRLTTIPP 221 Query: 562 D 564 D Sbjct: 222 D 222
>SLIT1_MOUSE (Q80TR4) Slit homolog 1 protein precursor (Slit-1)| Length = 1531 Score = 40.0 bits (92), Expect = 0.005 Identities = 47/185 (25%), Positives = 77/185 (41%), Gaps = 7/185 (3%) Frame = +1 Query: 19 NVVVLDVRSNQLKSL-PNSIGCLSKLRVLNVSGNLLQSLP-ATIEECRALEELNANFNQL 192 N L++ N + + N L +LRVL + N + ++ ++ + LE L N NQL Sbjct: 62 NTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQL 121 Query: 193 TRLPDTLGFELHSLRRLSVNSNKLTSLP----FSTSHMTALRALDARLNCIRAXXXXXXX 360 LP+ L +L RL ++ N L ++P + + L+ R++CI Sbjct: 122 QVLPELLFQNNQALSRLDLSENFLQAVPRKAFRGATDLKNLQLDKNRISCIEEGA----- 176 Query: 361 XXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLP-DSMGCLAKLNKFSAVG 537 F LR GL +LT ++ N+I+ +P S + KL F Sbjct: 177 ------------FRALR----GLEVLT------LNNNNITTIPVSSFNHMPKLRTFRLHS 214 Query: 538 NPLIC 552 N L C Sbjct: 215 NHLFC 219 Score = 33.9 bits (76), Expect = 0.34 Identities = 28/108 (25%), Positives = 51/108 (47%), Gaps = 5/108 (4%) Frame = +1 Query: 28 VLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLP-ATIEECRALEELNANFNQLTRLP 204 ++D R L ++P ++ + + + N ++S+P R L ++ + NQ+ + Sbjct: 292 IVDCRGKGLTAIPANLP--ETMTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIA 349 Query: 205 DTLGFELHSLRRLSVNSNKLTSLP---FSTSHMTALRALDA-RLNCIR 336 L SL L + NK+T LP F + L L+A ++NCIR Sbjct: 350 PDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIR 397
>LRTM2_MOUSE (Q8BGA3) Leucine-rich repeat transmembrane neuronal protein 2| precursor Length = 515 Score = 40.0 bits (92), Expect = 0.005 Identities = 40/137 (29%), Positives = 62/137 (45%), Gaps = 27/137 (19%) Frame = +1 Query: 10 RLLNVVVLDVRSNQLKSL-PNSIGCLSKLRVLNVSGNLLQSLPATIE-ECRALE------ 165 +L+N+ LD+ NQL SL P L KL+ L++ N L+++P + +CR+LE Sbjct: 131 QLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEFLDLST 190 Query: 166 ------------------ELNANFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTS- 288 EL+ NQLT++ L SL L + NK+++L Sbjct: 191 NRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLTCGMDW 250 Query: 289 HMTALRALDARLNCIRA 339 + L LD N I+A Sbjct: 251 TWSTLEKLDLTGNEIKA 267
>LRRN3_PONPY (Q5R482) Leucine-rich repeats neuronal protein 3 precursor| (Neuronal leucine-rich repeat protein 3) (NLRR-3) Length = 708 Score = 40.0 bits (92), Expect = 0.005 Identities = 28/85 (32%), Positives = 45/85 (52%), Gaps = 2/85 (2%) Frame = +1 Query: 16 LNVVVLDVRSNQLKSLPN-SIGCLSKLRVLNVSGNLLQSLPAT-IEECRALEELNANFNQ 189 +N+ LD+ N L S+ N ++ + +L + + N L LP + E L+EL N N Sbjct: 92 VNLTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQELYINHNL 151 Query: 190 LTRLPDTLGFELHSLRRLSVNSNKL 264 L+ + LH+L RL +NSN+L Sbjct: 152 LSTISPGAFIGLHNLLRLHLNSNRL 176
>LRRN3_HUMAN (Q9H3W5) Leucine-rich repeats neuronal protein 3 precursor| (Neuronal leucine-rich repeat protein 3) (NLRR-3) Length = 708 Score = 40.0 bits (92), Expect = 0.005 Identities = 28/85 (32%), Positives = 45/85 (52%), Gaps = 2/85 (2%) Frame = +1 Query: 16 LNVVVLDVRSNQLKSLPN-SIGCLSKLRVLNVSGNLLQSLPAT-IEECRALEELNANFNQ 189 +N+ LD+ N L S+ N ++ + +L + + N L LP + E L+EL N N Sbjct: 92 VNLTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQELYINHNL 151 Query: 190 LTRLPDTLGFELHSLRRLSVNSNKL 264 L+ + LH+L RL +NSN+L Sbjct: 152 LSTISPGAFIGLHNLLRLHLNSNRL 176
>LRRN3_MOUSE (Q8CBC6) Leucine-rich repeats neuronal protein 3 precursor| (Neuronal leucine-rich repeat protein 3) (NLRR-3) Length = 707 Score = 40.0 bits (92), Expect = 0.005 Identities = 30/88 (34%), Positives = 47/88 (53%), Gaps = 5/88 (5%) Frame = +1 Query: 16 LNVVVLDVRSNQLKSLPN-SIGCLSKLRVLNVSGNLLQSLPATIEEC----RALEELNAN 180 +N+ LD+ N L S+ N ++ +S+L + + N L LP E+C L+EL N Sbjct: 92 VNLTGLDLSQNNLSSVTNINVQKMSQLLSVYLEENKLTELP---EKCLYGLSNLQELYVN 148 Query: 181 FNQLTRLPDTLGFELHSLRRLSVNSNKL 264 N L+ + LH+L RL +NSN+L Sbjct: 149 HNLLSTISPGAFIGLHNLLRLHLNSNRL 176
>LRFN4_HUMAN (Q6PJG9) Leucine-rich repeat and fibronectin type-III| domain-containing protein 4 precursor Length = 635 Score = 40.0 bits (92), Expect = 0.005 Identities = 37/146 (25%), Positives = 65/146 (44%), Gaps = 3/146 (2%) Frame = +1 Query: 100 LNVSGNLLQSL-PATIEECRALEELNANFNQLTRLPDTLGFELHSLRRLSVNSNKLTSL- 273 L ++ N +Q+L P L +L + N +TR+ +L SLR L ++ N+L L Sbjct: 53 LRLADNFIQALGPPDFRNMTGLVDLTLSRNAITRIGARAFGDLESLRSLHLDGNRLVELG 112 Query: 274 PFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHFLRELPY-GLGLLTSLR 450 S L+ L N + +++ LR++P+ G+G + +L Sbjct: 113 TGSLRGPVNLQHLILSGNQLGRIAPGAFDDFLESLEDLDLSYNNLRQVPWAGIGAMPALH 172 Query: 451 ELDISYNSISVLPDSMGCLAKLNKFS 528 L++ +N I LP G A+L + S Sbjct: 173 TLNLDHNLIDALPP--GAFAQLGQLS 196 Score = 31.6 bits (70), Expect = 1.7 Identities = 22/64 (34%), Positives = 32/64 (50%), Gaps = 3/64 (4%) Frame = +1 Query: 31 LDVRSNQLKSLP-NSIGCLSKLRVLNVSGNLLQSL-PATIEECRALEELNANFNQLTRL- 201 LD+ N L+ +P IG + L LN+ NL+ +L P + L L+ N+L L Sbjct: 150 LDLSYNNLRQVPWAGIGAMPALHTLNLDHNLIDALPPGAFAQLGQLSRLDLTSNRLATLA 209 Query: 202 PDTL 213 PD L Sbjct: 210 PDPL 213
>OMD_BOVIN (O77742) Osteomodulin precursor (Osteoadherin) (OSAD) (Keratan| sulfate proteoglycan osteomodulin) (KSPG osteomodulin) Length = 422 Score = 40.0 bits (92), Expect = 0.005 Identities = 27/111 (24%), Positives = 57/111 (51%), Gaps = 3/111 (2%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSL---PNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 L+N+ +LD+ N++ + + KL LN+ N L+S+P + +L L+ Sbjct: 185 LVNLTMLDLCFNKIDDSVLQEKVLAKMEKLMQLNLCNNRLESMPPGLPS--SLMYLSLEN 242 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIR 336 N ++ +P+ +L L L ++ NKL +P++ +++ L L+ N ++ Sbjct: 243 NSISSIPENYFNKLPKLHALRISHNKLQDIPYNIFNLSNLIELNVGHNKLK 293
>TLR9_MOUSE (Q9EQU3) Toll-like receptor 9 precursor (CD289 antigen)| Length = 1032 Score = 39.7 bits (91), Expect = 0.006 Identities = 37/116 (31%), Positives = 52/116 (44%), Gaps = 10/116 (8%) Frame = +1 Query: 19 NVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPAT---------IEECRALEEL 171 N++VLD NS+ L LRVL + GN P T + L L Sbjct: 154 NILVLDA---------NSLAGLYSLRVLFMDGNCYYKNPCTGAVKVTPGALLGLSNLTHL 204 Query: 172 NANFNQLTRLPDTLGFELHSLRRLSVNSNKLTSL-PFSTSHMTALRALDARLNCIR 336 + +N LT++P L SL L V+ N + L P +++T+LR LD NC R Sbjct: 205 SLKYNNLTKVPRQLP---PSLEYLLVSYNLIVKLGPEDLANLTSLRVLDVGGNCRR 257 Score = 32.7 bits (73), Expect = 0.75 Identities = 31/87 (35%), Positives = 48/87 (55%), Gaps = 3/87 (3%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSLPN-SIGCLSKLRVLNVSGNLLQS-LPATIEECRALEELNANFN 186 L N+ VLD+ NQLK+L N ++ + L+ L+VS N + S +PA L+E+N + N Sbjct: 677 LPNLEVLDLAGNQLKALTNGTLPNGTLLQKLDVSSNSIVSVVPAFFALAVELKEVNLSHN 736 Query: 187 QLTRLPDT-LGFELHSLRRLSVNSNKL 264 L + + G + +L L V SN L Sbjct: 737 ILKTVDRSWFGPIVMNLTVLDVRSNPL 763
>TLR8_MOUSE (P58682) Toll-like receptor 8 precursor| Length = 1032 Score = 39.7 bits (91), Expect = 0.006 Identities = 35/112 (31%), Positives = 54/112 (48%), Gaps = 4/112 (3%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSLPNS--IGCLSKLRVLNVSGNLLQSLPATI-EECRALEELNANF 183 L N++ LD+ N L+ +PN + L+ L +SGN L+ T+ + L L+ + Sbjct: 629 LQNLIRLDLSYNNLQQIPNGAFLNLPQSLQELLISGNKLRFFNWTLLQYFPHLHLLDLSR 688 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFS-TSHMTALRALDARLNCIR 336 N+L LP+ L HSL L ++ N + LP S L LD N I+ Sbjct: 689 NELYFLPNCLSKFAHSLETLLLSHNHFSHLPSGFLSEARNLVHLDLSFNTIK 740
>DRL42_ARATH (Q9FKZ1) Probable disease resistance protein At5g66900| Length = 809 Score = 39.7 bits (91), Expect = 0.006 Identities = 44/151 (29%), Positives = 73/151 (48%), Gaps = 6/151 (3%) Frame = +1 Query: 82 LSKLRVLNVSGNL-LQSLPATIEECRALEELN-ANFNQLTRLPDTLGFELHSLRRLSV-- 249 LSKL+ +++ L LP I E +L+ L+ N N+L++LP+ +G +L RL V Sbjct: 648 LSKLQEIDIDYCYDLDELPYWISEIVSLKTLSITNCNKLSQLPEAIG----NLSRLEVLR 703 Query: 250 --NSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHFLRELPY 423 +S L+ LP +T ++ LR LD +C+ LR+LP Sbjct: 704 LCSSMNLSELPEATEGLSNLRFLDIS-HCLG-----------------------LRKLPQ 739 Query: 424 GLGLLTSLRELDISYNSISVLPDSMGCLAKL 516 +G L +L+++ + S LP+S+ L L Sbjct: 740 EIGKLQNLKKISMRKCSGCELPESVTNLENL 770
>SLIT1_RAT (O88279) Slit homolog 1 protein precursor (Slit-1) (Multiple| epidermal growth factor-like domains 4) Length = 1531 Score = 39.7 bits (91), Expect = 0.006 Identities = 46/185 (24%), Positives = 77/185 (41%), Gaps = 7/185 (3%) Frame = +1 Query: 19 NVVVLDVRSNQLKSL-PNSIGCLSKLRVLNVSGNLLQSLP-ATIEECRALEELNANFNQL 192 N L++ N + + N L +LRVL + N + ++ ++ + LE L N NQL Sbjct: 62 NTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQL 121 Query: 193 TRLPDTLGFELHSLRRLSVNSNKLTSLP----FSTSHMTALRALDARLNCIRAXXXXXXX 360 LP+ L +L RL ++ N L ++P + + L+ +++CI Sbjct: 122 QVLPELLFQNNQALSRLDLSENSLQAVPRKAFRGATDLKNLQLDKNQISCIEEGA----- 176 Query: 361 XXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLP-DSMGCLAKLNKFSAVG 537 F LR GL +LT ++ N+I+ +P S + KL F Sbjct: 177 ------------FRALR----GLEVLT------LNNNNITTIPVSSFNHMPKLRTFRLHS 214 Query: 538 NPLIC 552 N L C Sbjct: 215 NHLFC 219 Score = 33.9 bits (76), Expect = 0.34 Identities = 28/108 (25%), Positives = 51/108 (47%), Gaps = 5/108 (4%) Frame = +1 Query: 28 VLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLP-ATIEECRALEELNANFNQLTRLP 204 ++D R L ++P ++ + + + N ++S+P R L ++ + NQ+ + Sbjct: 292 IVDCRGKGLTAIPANLP--ETMTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIA 349 Query: 205 DTLGFELHSLRRLSVNSNKLTSLP---FSTSHMTALRALDA-RLNCIR 336 L SL L + NK+T LP F + L L+A ++NCIR Sbjct: 350 PDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIR 397
>LRRK1_MOUSE (Q3UHC2) Leucine-rich repeat serine/threonine-protein kinase 1 (EC| 2.7.11.1) Length = 2014 Score = 39.7 bits (91), Expect = 0.006 Identities = 45/160 (28%), Positives = 64/160 (40%), Gaps = 8/160 (5%) Frame = +1 Query: 34 DVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIE-ECRALEELNANFNQLTRLPDT 210 D N LK +P + L L L + GN L SLP + C L+ L+ + NQL + D Sbjct: 456 DFSENSLKEVPLGLFQLDALMFLRLQGNQLLSLPPQEKWTCTQLKTLDLSRNQLGKNEDG 515 Query: 211 LG------FELHSLRRLSVNSNKLTSLP-FSTSHMTALRALDARLNCIRAXXXXXXXXXX 369 L F +R + + P F + + L D L+ + Sbjct: 516 LKTKRISLFTTRGRQRSGTETASMLEFPAFLSESLEVLCLNDNHLDAVPPSVCLLKNLSE 575 Query: 370 XXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLP 489 N LRELP LG L +L +LDI +IS +P Sbjct: 576 LYLG----NNPGLRELPPELGQLGNLWQLDIEDLNISNVP 611
>CHAO_DROME (P12024) Chaoptin precursor (Photoreceptor cell-specific membrane| protein) Length = 1315 Score = 39.7 bits (91), Expect = 0.006 Identities = 28/94 (29%), Positives = 49/94 (52%), Gaps = 4/94 (4%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPN-SIGCLSKLRVLNVSGNLL-QSLPATIEEC--RALEEL 171 + L ++ LD +N + S+ + S L LR+L + N + Q L T + LEE+ Sbjct: 522 LRHLTSLQELDFSNNHISSMSDTSFHFLKNLRLLELHDNRIEQVLKGTFQGDIHSKLEEI 581 Query: 172 NANFNQLTRLPDTLGFELHSLRRLSVNSNKLTSL 273 + FN LT + F+L +LR+L ++ NK+ + Sbjct: 582 SLRFNHLTSISQHTFFDLEALRKLHLDDNKIDKI 615 Score = 38.9 bits (89), Expect = 0.010 Identities = 46/200 (23%), Positives = 79/200 (39%), Gaps = 27/200 (13%) Frame = +1 Query: 28 VLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRA---LEELNANFNQLTR 198 ++D N L+ LP+++ + L+VS N++ +P++ A L EL+ + N ++ Sbjct: 808 IVDFSHNHLRGLPDNLFYNGGMEKLDVSHNMMLKIPSSSLSSLAALTLCELHLSNNFIST 867 Query: 199 LPDT-LGFELHSLRRLSVNSNKLTSLP---FST---------SHMTALRALDARLNCIRA 339 + L + SLR L ++ N L + F+T SH L+ +D + Sbjct: 868 IHSMDLSNKFRSLRYLDISYNYLLRIDDAVFATMPKLAVLDLSHNRDLKVMDKSFMGLEN 927 Query: 340 XXXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTS-----------LRELDISYNSISVL 486 +LRE G L S LR LD+S N ++ + Sbjct: 928 SLIKLGLENISLSTVPEIRLKYLREFRLGYNELPSIPQELAHNMSNLRMLDLSNNDLTNV 987 Query: 487 PDSMGCLAKLNKFSAVGNPL 546 P L L + GNP+ Sbjct: 988 PLMTQALPHLRRLMLSGNPI 1007 Score = 35.4 bits (80), Expect = 0.12 Identities = 42/155 (27%), Positives = 65/155 (41%), Gaps = 6/155 (3%) Frame = +1 Query: 31 LDVRSNQLKSLPNSI--GCLSKLRVLNVSGNLLQSLPA-TIEECRALEELNANFNQLTRL 201 L + N L +P+ G L L + N L +P+ ++ + L L+ +N +T + Sbjct: 107 LKISGNHLTEIPDDAFTGLERSLWELILPQNDLVEIPSKSLRHLQKLRHLDLGYNHITHI 166 Query: 202 P-DTLGFELHSLRRLSVNSNKLTSL-PFSTSHMTALRALDARLNCIRAXXXXXXXXXXXX 375 D+ SL+ L + N ++ L S S + L LD N + Sbjct: 167 QHDSFRGLEDSLQTLILRENCISQLMSHSFSGLLILETLDLSGNNLFEIDPNVFVDGMPR 226 Query: 376 XXXXSQNFHFLRELPY-GLGLLTSLRELDISYNSI 477 + L E+PY LG L SLR LDIS+N I Sbjct: 227 LTRLLLTDNILSEIPYDALGPLKSLRTLDISHNVI 261
>LRRN3_RAT (Q9ESY6) Leucine-rich repeats neuronal protein 3 precursor| (Neuronal leucine-rich repeat protein 3) (NLRR-3) Length = 707 Score = 39.7 bits (91), Expect = 0.006 Identities = 30/88 (34%), Positives = 47/88 (53%), Gaps = 5/88 (5%) Frame = +1 Query: 16 LNVVVLDVRSNQLKSLPN-SIGCLSKLRVLNVSGNLLQSLPATIEEC----RALEELNAN 180 +N+ LD+ N L S+ N ++ +S+L + + N L LP E+C L+EL N Sbjct: 92 VNLTGLDLSQNNLSSVTNINVQKMSQLLSVYLEENKLTELP---EKCLYGLSNLQELYVN 148 Query: 181 FNQLTRLPDTLGFELHSLRRLSVNSNKL 264 N L+ + LH+L RL +NSN+L Sbjct: 149 HNLLSAISPGAFVGLHNLLRLHLNSNRL 176
>ALS_MOUSE (P70389) Insulin-like growth factor-binding protein complex acid| labile chain precursor (ALS) Length = 603 Score = 39.7 bits (91), Expect = 0.006 Identities = 45/161 (27%), Positives = 66/161 (40%), Gaps = 3/161 (1%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSLPNSI-GCLSKLRVLNVSGNLLQSLPATI-EECRALEELNANFN 186 L N+ L + N L+SL + L L++ NLL L + L +LN +N Sbjct: 121 LQNLYHLHLERNLLRSLAAGLFRHTPSLASLSLGNNLLGRLEEGLFRGLSHLWDLNLGWN 180 Query: 187 QLTRLPDTLGFELHSLRRLSVNSNKLTSL-PFSTSHMTALRALDARLNCIRAXXXXXXXX 363 L LPDT+ L +L L + NKLT L P + LR LD N +R+ Sbjct: 181 SLVVLPDTVFQGLGNLHELVLAGNKLTYLQPALLCGLGELRELDLSRNALRSVKANVFIH 240 Query: 364 XXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVL 486 P + +LR LD+S+N ++ L Sbjct: 241 LPRLQKLYLDRNLITAVAPRAFLGMKALRWLDLSHNRVAGL 281 Score = 36.2 bits (82), Expect = 0.068 Identities = 42/185 (22%), Positives = 80/185 (43%), Gaps = 4/185 (2%) Frame = +1 Query: 31 LDVRSNQLKSL-PNSIGCLSKLRVLNVSGNLLQSL-PATIEECRALEELNANFNQLTRLP 204 LD+ N++ L ++ L L VL ++ N + SL P T ++ LEEL N++ +L Sbjct: 271 LDLSHNRVAGLLEDTFPGLLGLHVLRLAHNAITSLRPRTFKDLHFLEELQLGHNRIRQLG 330 Query: 205 DTLGFELHSLRRLSVNSNKLTSLPFSTSH-MTALRALDARLNCIRAXXXXXXXXXXXXXX 381 + L L L++N N++ + + + ++ NC+R+ Sbjct: 331 EKTFEGLGQLEVLTLNDNQIHEVKVGAFFGLFNVAVMNLSGNCLRSLPEHVFQGLGRLHS 390 Query: 382 XXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPD-SMGCLAKLNKFSAVGNPLICPP 558 ++ R + L+ LR L + NSIS + + S+ L++L + N L P Sbjct: 391 LHLEHSCLGRIRLHTFAGLSGLRRLFLRDNSISSIEEQSLAGLSELLELDLTANQLTHLP 450 Query: 559 MDIVE 573 + + Sbjct: 451 RQLFQ 455 Score = 32.3 bits (72), Expect = 0.98 Identities = 47/172 (27%), Positives = 69/172 (40%), Gaps = 4/172 (2%) Frame = +1 Query: 43 SNQLKSLPNSIGCLSKLRVLNVSGNLLQSLP-ATIEECRALEELNANFNQLTRLPDTLGF 219 S L LP+ I + R L + GN L S+P A + +L+ LN + L L Sbjct: 62 SRNLTQLPDGIPVST--RALWLDGNNLSSIPSAAFQNLSSLDFLNLQGSWLRSLEPQALL 119 Query: 220 ELHSLRRLSVNSNKLTSLPFST-SHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQN 396 L +L L + N L SL H +L +L N Sbjct: 120 GLQNLYHLHLERNLLRSLAAGLFRHTPSLASLSLGNN----------------------- 156 Query: 397 FHFLRELPYGLGL-LTSLRELDISYNSISVLPDSM-GCLAKLNKFSAVGNPL 546 L L GL L+ L +L++ +NS+ VLPD++ L L++ GN L Sbjct: 157 --LLGRLEEGLFRGLSHLWDLNLGWNSLVVLPDTVFQGLGNLHELVLAGNKL 206
>LRTM2_HUMAN (O43300) Leucine-rich repeat transmembrane neuronal protein 2| precursor (Leucine-rich repeat neuronal 2 protein) Length = 516 Score = 39.7 bits (91), Expect = 0.006 Identities = 34/114 (29%), Positives = 54/114 (47%), Gaps = 26/114 (22%) Frame = +1 Query: 10 RLLNVVVLDVRSNQLKSL-PNSIGCLSKLRVLNVSGNLLQSLPATIE-ECRALE------ 165 +L+N+ LD+ NQL SL P L KL+ L++ N L+++P + +CR+LE Sbjct: 131 QLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEFLDLST 190 Query: 166 ------------------ELNANFNQLTRLPDTLGFELHSLRRLSVNSNKLTSL 273 EL+ NQLT++ L SL L + NK+++L Sbjct: 191 NRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNL 244
>PSKR_ARATH (Q9ZVR7) Putative phytosulfokine receptor precursor (EC 2.7.11.1)| (Phytosulfokine LRR receptor kinase) Length = 1008 Score = 39.3 bits (90), Expect = 0.008 Identities = 33/107 (30%), Positives = 61/107 (57%), Gaps = 5/107 (4%) Frame = +1 Query: 22 VVVLDVRSNQLKS-LPNSIGCLSKLRVLNVSGNLLQ-SLPATIEECRALEELNANFNQLT 195 V+ L++ + +L L S+G L ++RVLN+S N ++ S+P +I + L+ L+ + N L+ Sbjct: 78 VIRLELGNKKLSGKLSESLGKLDEIRVLNLSRNFIKDSIPLSIFNLKNLQTLDLSSNDLS 137 Query: 196 -RLPDTLGFELHSLRRLSVNSNKLT-SLPFSTSH-MTALRALDARLN 327 +P ++ L +L+ ++SNK SLP H T +R + +N Sbjct: 138 GGIPTSI--NLPALQSFDLSSNKFNGSLPSHICHNSTQIRVVKLAVN 182 Score = 37.7 bits (86), Expect = 0.023 Identities = 52/182 (28%), Positives = 83/182 (45%), Gaps = 19/182 (10%) Frame = +1 Query: 58 SLPNSIGCLSKLRVLNVSGNLLQ-SLPATIEECRALEELNANFNQLT-RLPDTLGFELHS 231 S+P + ++L++L++S N L ++P+ I + +AL L+ + N T +P +L +L S Sbjct: 430 SMPRWLSSSNELQLLDLSWNRLTGAIPSWIGDFKALFYLDLSNNSFTGEIPKSLT-KLES 488 Query: 232 L--RRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHF 405 L R +SVN PF + RAL + N I + F Sbjct: 489 LTSRNISVNEPS-PDFPFFMKRNESARAL--QYNQIFGFPPTIELGHNNLSGPIWEEFGN 545 Query: 406 LREL--------------PYGLGLLTSLRELDISYNSIS-VLPDSMGCLAKLNKFSAVGN 540 L++L P L +TSL LD+S N +S +P S+ L+ L+KFS N Sbjct: 546 LKKLHVFDLKWNALSGSIPSSLSGMTSLEALDLSNNRLSGSIPVSLQQLSFLSKFSVAYN 605 Query: 541 PL 546 L Sbjct: 606 NL 607
>CHAD_MOUSE (O55226) Chondroadherin precursor (Cartilage leucine-rich protein)| Length = 358 Score = 39.3 bits (90), Expect = 0.008 Identities = 25/93 (26%), Positives = 50/93 (53%), Gaps = 2/93 (2%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSL-PNSIGCLSKLRVLNVSGNLLQSL-PATIEECRALEELNA 177 ++ L+N+ +L + +N+++ L + LR L +S N L SL P ++++ L + + Sbjct: 142 LSPLVNLFILQLNNNKIRELRAGAFQGAKDLRWLYLSENALSSLQPGSLDDVENLAKFHL 201 Query: 178 NFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLP 276 + NQL+ P +L + L ++ N L S+P Sbjct: 202 DKNQLSSYPSAALSKLRVVEELKLSHNPLKSIP 234
>TLR7_HUMAN (Q9NYK1) Toll-like receptor 7 precursor| Length = 1049 Score = 39.3 bits (90), Expect = 0.008 Identities = 27/84 (32%), Positives = 42/84 (50%), Gaps = 2/84 (2%) Frame = +1 Query: 19 NVVVLDVRSNQLKSLP-NSIGCLSKLRVLNVSGNLLQSLPATIEEC-RALEELNANFNQL 192 N+ L + N LKS + CL L L++S N L ++P + C R+L+ L NQ+ Sbjct: 676 NLKNLSLAKNGLKSFSWKKLQCLKNLETLDLSHNQLTTVPERLSNCSRSLKNLILKNNQI 735 Query: 193 TRLPDTLGFELHSLRRLSVNSNKL 264 L + LR L ++SNK+ Sbjct: 736 RSLTKYFLQDAFQLRYLDLSSNKI 759 Score = 38.9 bits (89), Expect = 0.010 Identities = 55/191 (28%), Positives = 79/191 (41%), Gaps = 19/191 (9%) Frame = +1 Query: 31 LDVRSNQLKSLPNS-IGCLSKLRVLNVSGNLL-QSLPAT-IEECRALEELNANFNQLTRL 201 LD+ N + + +S LS L+ LN+SGNL+ Q+L + + L L+ + N+L L Sbjct: 498 LDLSKNSIFFVKSSDFQHLSFLKCLNLSGNLISQTLNGSEFQPLAELRYLDFSNNRLDLL 557 Query: 202 PDTLGFELHSLRRLSVNSNK-------LTSLPFSTSHMTALRALDARLNCIRAXXXXXXX 360 T ELH L L ++SN +T + T ++ L+ L N I + Sbjct: 558 HSTAFEELHKLEVLDISSNSHYFQSEGITHMLNFTKNLKVLQKLMMNDNDISSSTSRTME 617 Query: 361 XXXXXXXXXSQNFHFL-------RELPYGLGLLTSLRELDISYNSISVLPDSM--GCLAK 513 N + R L LL L ELDIS NS+S LP + G Sbjct: 618 SESLRTLEFRGNHLDVLWREGDNRYLQLFKNLL-KLEELDISKNSLSFLPSGVFDGMPPN 676 Query: 514 LNKFSAVGNPL 546 L S N L Sbjct: 677 LKNLSLAKNGL 687
>SLIT1_HUMAN (O75093) Slit homolog 1 protein precursor (Slit-1) (Multiple| epidermal growth factor-like domains 4) Length = 1534 Score = 39.3 bits (90), Expect = 0.008 Identities = 45/185 (24%), Positives = 77/185 (41%), Gaps = 7/185 (3%) Frame = +1 Query: 19 NVVVLDVRSNQLKSL-PNSIGCLSKLRVLNVSGNLLQSLP-ATIEECRALEELNANFNQL 192 N L++ N + + N L +LRVL + N + ++ ++ + LE L N NQL Sbjct: 62 NTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQL 121 Query: 193 TRLPDTLGFELHSLRRLSVNSNKLTSLP----FSTSHMTALRALDARLNCIRAXXXXXXX 360 LP+ L +L RL ++ N + ++P + + L+ +++CI Sbjct: 122 HMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGA----- 176 Query: 361 XXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLP-DSMGCLAKLNKFSAVG 537 F LR GL +LT ++ N+I+ +P S + KL F Sbjct: 177 ------------FRALR----GLEVLT------LNNNNITTIPVSSFNHMPKLRTFRLHS 214 Query: 538 NPLIC 552 N L C Sbjct: 215 NHLFC 219 Score = 33.9 bits (76), Expect = 0.34 Identities = 28/108 (25%), Positives = 51/108 (47%), Gaps = 5/108 (4%) Frame = +1 Query: 28 VLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLP-ATIEECRALEELNANFNQLTRLP 204 ++D R L ++P ++ + + + N ++S+P R L ++ + NQ+ + Sbjct: 292 IVDCRGKGLTAIPANLP--ETMTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIA 349 Query: 205 DTLGFELHSLRRLSVNSNKLTSLP---FSTSHMTALRALDA-RLNCIR 336 L SL L + NK+T LP F + L L+A ++NCIR Sbjct: 350 PDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIR 397
>SLIK2_HUMAN (Q9H156) SLIT and NTRK-like protein 2 precursor| Length = 845 Score = 39.3 bits (90), Expect = 0.008 Identities = 31/108 (28%), Positives = 54/108 (50%), Gaps = 2/108 (1%) Frame = +1 Query: 19 NVVVLDVRSNQLKSL-PNSIGCLSKLRVLNVSGNLLQSLPA-TIEECRALEELNANFNQL 192 N V L + +N L+ + + L L+ L+++ N L+ L T +LE L A++N + Sbjct: 87 NAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILREDTFLGLESLEYLQADYNYI 146 Query: 193 TRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIR 336 + + +L+ L+ L +N N L SLP + L LD R N ++ Sbjct: 147 SAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVLLTHLDLRGNRLK 194 Score = 37.0 bits (84), Expect = 0.040 Identities = 27/83 (32%), Positives = 45/83 (54%), Gaps = 1/83 (1%) Frame = +1 Query: 82 LSKLRVLNVSGNLLQSL-PATIEECRALEELNANFNQLTRLPDTLGFELHSLRRLSVNSN 258 L+ LR L ++GN L+ L P+ + ++L+ L +N + + L +L+ L +N+N Sbjct: 422 LTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNN 481 Query: 259 KLTSLPFSTSHMTALRALDARLN 327 L SLP + TAL L+ R N Sbjct: 482 LLRSLPDNIFGGTALTRLNLRNN 504 Score = 33.5 bits (75), Expect = 0.44 Identities = 43/156 (27%), Positives = 67/156 (42%), Gaps = 5/156 (3%) Frame = +1 Query: 100 LNVSGNLLQSLPAT-IEECRALEELNANFNQLTRLPDTLGFELHSLRRLSVNSNKLTSL- 273 L ++GN LQ++ + E +L+ L+ N++ + + L SLRRL +N N L L Sbjct: 380 LYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVLY 439 Query: 274 PFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRE 453 P + +L+ L N I+ N + LR LP + T+L Sbjct: 440 PSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNN-NLLRSLPDNIFGGTALTR 498 Query: 454 LDISYNSISVLPDSMGCLAKLNKFSAVG---NPLIC 552 L++ N S LP G L +L F + NP C Sbjct: 499 LNLRNNHFSHLP-VKGVLDQLPAFIQIDLQENPWDC 533 Score = 32.0 bits (71), Expect = 1.3 Identities = 22/65 (33%), Positives = 34/65 (52%), Gaps = 1/65 (1%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSL-PNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQ 189 L ++ L + N +K + P + L L++L ++ NLL+SLP I AL LN N Sbjct: 446 LQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIFGGTALTRLNLRNNH 505 Query: 190 LTRLP 204 + LP Sbjct: 506 FSHLP 510 Score = 29.3 bits (64), Expect = 8.3 Identities = 16/41 (39%), Positives = 25/41 (60%) Frame = +1 Query: 82 LSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLP 204 L+KL+VL ++ NLL SLP+ + L L+ N+L +P Sbjct: 157 LNKLKVLILNDNLLLSLPSNVFRFVLLTHLDLRGNRLKVMP 197
>AMGO1_HUMAN (Q86WK6) Amphoterin-induced protein 1 precursor (Alivin-2)| Length = 493 Score = 38.9 bits (89), Expect = 0.010 Identities = 30/93 (32%), Positives = 51/93 (54%), Gaps = 7/93 (7%) Frame = +1 Query: 19 NVVVLDVRSNQLKSLPNSIGCLSKLRVLNV----SGNLLQSLPATIEECRALEELNANFN 186 N+ LD+ SNQL++L + S L+VL V + +++ ++ L++L + N Sbjct: 111 NLRYLDLSSNQLRTLDEFL--FSDLQVLEVLLLYNNHIMAVDRCAFDDMAQLQKLYLSQN 168 Query: 187 QLTRLPDTL---GFELHSLRRLSVNSNKLTSLP 276 Q++R P L G +L L L ++SNKL +LP Sbjct: 169 QISRFPLELVKEGAKLPKLTLLDLSSNKLKNLP 201
>LUM_BOVIN (Q05443) Lumican precursor (Keratan sulfate proteoglycan) (KSPG)| (Corneal keratan sulfate proteoglycan 37B core protein) Length = 342 Score = 38.9 bits (89), Expect = 0.010 Identities = 41/160 (25%), Positives = 77/160 (48%), Gaps = 3/160 (1%) Frame = +1 Query: 19 NVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQ--SLPATIEECRALEELNANFNQL 192 ++V L + +N++ L + G L L +++ N L+ ++ A ++ ++LE L+ +FNQ+ Sbjct: 142 SLVDLQLTNNKISKLGSFDG-LVNLTFIHLQHNQLKEDAVSAALKGLKSLEYLDLSFNQM 200 Query: 193 TRLPDTLGFELHSLRRLSVNSNKLTSLPFS-TSHMTALRALDARLNCIRAXXXXXXXXXX 369 T+LP L SL L +++NK++++P +AL+ L Sbjct: 201 TKLPSGLPV---SLLTLYLDNNKISNIPDEYFKRFSALQYL------------------- 238 Query: 370 XXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLP 489 S N +P ++SL ELD+SYN + +P Sbjct: 239 ----RLSHNELADSGVPGNSFNVSSLLELDLSYNKLKSIP 274 Score = 32.0 bits (71), Expect = 1.3 Identities = 27/91 (29%), Positives = 46/91 (50%), Gaps = 3/91 (3%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPAT-IEECRALEELNANFNQ 189 L ++ LD+ NQ+ LP+ G L L + N + ++P + AL+ L + N+ Sbjct: 187 LKSLEYLDLSFNQMTKLPS--GLPVSLLTLYLDNNKISNIPDEYFKRFSALQYLRLSHNE 244 Query: 190 L--TRLPDTLGFELHSLRRLSVNSNKLTSLP 276 L + +P F + SL L ++ NKL S+P Sbjct: 245 LADSGVPGN-SFNVSSLLELDLSYNKLKSIP 274
>LGR8_HUMAN (Q8WXD0) Relaxin receptor 2 (Leucine-rich repeat-containing| G-protein coupled receptor 8) (G-protein coupled receptor affecting testicular descent) (G-protein coupled receptor 106) Length = 754 Score = 38.9 bits (89), Expect = 0.010 Identities = 52/207 (25%), Positives = 85/207 (41%), Gaps = 30/207 (14%) Frame = +1 Query: 19 NVVVLDVRSNQLKSLPNSI--------------GC-----------LSKLRVLNVSGNLL 123 NV +L ++ N++ SLP+ + C L L++L ++ N + Sbjct: 138 NVTLLSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKAFFGLCNLQILYLNHNCI 197 Query: 124 QSL-PATIEECRALEELNANFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFS-TSHMT 297 +L P ++ L L + N +TR+ L L+SL LS+ +N L +LP + M Sbjct: 198 TTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQMP 257 Query: 298 ALRALDARLNCIR--AXXXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYN 471 L +D N I+ F+ E + L +L ELD+S N Sbjct: 258 QLNWVDLEGNRIKYLTNSTFLSCDSLTVLFLPRNQIGFVPEKTF--SSLKNLGELDLSSN 315 Query: 472 SISVL-PDSMGCLAKLNKFSAVGNPLI 549 +I+ L P L L K + NPL+ Sbjct: 316 TITELSPHLFKDLKLLQKLNLSSNPLM 342
>TLR9_PIG (Q5I2M3) Toll-like receptor 9 precursor (CD289 antigen)| Length = 1030 Score = 38.9 bits (89), Expect = 0.010 Identities = 35/108 (32%), Positives = 51/108 (47%), Gaps = 9/108 (8%) Frame = +1 Query: 40 RSNQLKSLPNSIGCLSKLRVLNVSGNL---------LQSLPATIEECRALEELNANFNQL 192 R+N L P + L LR L + GN L+ +P + L L+ +N L Sbjct: 151 RTNILVLDPTHLTGLHALRYLYMDGNCYYKNPCQGALEVVPGALLGLGNLTHLSLKYNNL 210 Query: 193 TRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIR 336 T +P +L L +L LS N + +T P +++TALR LD NC R Sbjct: 211 TEVPRSLPPSLETLL-LSYN-HIVTLTPEDLANLTALRVLDVGGNCRR 256 Score = 32.7 bits (73), Expect = 0.75 Identities = 48/179 (26%), Positives = 71/179 (39%), Gaps = 9/179 (5%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPAT-------IEECRAL 162 +A+L + L + N + S + C + L L+ SGN L + A + R+L Sbjct: 570 VAQLPALRYLSLAHNDIHSRVSQQLCSASLCALDFSGNDLSRMWAEGDLYLRFFQGLRSL 629 Query: 163 EELNANFNQL-TRLPDTLGFELHSLRRLSVNSNKLTSLPFST-SHMTALRALDARLNCIR 336 L+ + N L T LP L SL+ L + N L +S+ + + L LD N ++ Sbjct: 630 VWLDLSQNHLHTLLPRALDNLPKSLKHLHLRDNNLAFFNWSSLTLLPKLETLDLAGNQLK 689 Query: 337 AXXXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAK 513 A LP G T LR LD+S NSI + LAK Sbjct: 690 ALSNGS--------------------LPSG----TQLRRLDLSGNSIGFVNPGFFALAK 724
>DRL21_ARATH (Q9LRR5) Putative disease resistance protein At3g14460| Length = 1424 Score = 38.9 bits (89), Expect = 0.010 Identities = 26/87 (29%), Positives = 45/87 (51%) Frame = +1 Query: 55 KSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDTLGFELHSL 234 K L + LS LR+L++S + +LP +++ + L L+ + ++ LP+ + + Sbjct: 563 KVLNPLLNALSGLRILSLSHYQITNLPKSLKGLKLLRYLDLSSTKIKELPEFVCTLCNLQ 622 Query: 235 RRLSVNSNKLTSLPFSTSHMTALRALD 315 L N LTSLP S + + LR LD Sbjct: 623 TLLLSNCRDLTSLPKSIAELINLRLLD 649
>LGR8_CANFA (Q5XM32) Relaxin receptor 2 (Leucine-rich repeat-containing| G-protein coupled receptor 8) (INSL3 receptor) Length = 737 Score = 38.9 bits (89), Expect = 0.010 Identities = 51/207 (24%), Positives = 83/207 (40%), Gaps = 30/207 (14%) Frame = +1 Query: 19 NVVVLDVRSNQLKSLPNSI--------------GCLS-----------KLRVLNVSGNLL 123 N +L ++ N++ SLP+ + C++ L++L +S N + Sbjct: 121 NTTLLSLKKNKIHSLPDKVFTKYTQLKQIFLQHNCITHISRKAFFGLHNLQILYLSHNCI 180 Query: 124 QSL-PATIEECRALEELNANFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFS-TSHMT 297 +L P ++ L L + N +TR+ L L SL LS+ +N L +LP + M Sbjct: 181 TTLRPGVFKDLHQLTWLILDDNPITRISQQLFTGLKSLFFLSMVNNYLEALPKQMCAQMP 240 Query: 298 ALRALDARLNCIR--AXXXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYN 471 L +D N I+ F+ E + L +L ELD+S N Sbjct: 241 QLNWMDLEGNGIKYLTNSSFLSCNSLTVLFLPRNQIDFVPEKTF--SSLKNLGELDLSSN 298 Query: 472 SISVL-PDSMGCLAKLNKFSAVGNPLI 549 I L P+ L L K + NPL+ Sbjct: 299 MIMELPPEIFKDLKLLQKLNLSSNPLL 325
>CHAD_RAT (O70210) Chondroadherin precursor (Cartilage leucine-rich protein)| Length = 358 Score = 38.9 bits (89), Expect = 0.010 Identities = 25/93 (26%), Positives = 50/93 (53%), Gaps = 2/93 (2%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSL-PNSIGCLSKLRVLNVSGNLLQSL-PATIEECRALEELNA 177 ++ L+N+ +L + +N+++ L + LR L +S N L SL P ++++ L + + Sbjct: 142 LSPLVNLFILQLNNNKIRELRAGAFQGAKDLRWLYLSENALTSLHPGSLDDVENLAKFHL 201 Query: 178 NFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLP 276 + NQL+ P +L + L ++ N L S+P Sbjct: 202 DRNQLSSYPSAALSKLRVVEELKLSHNPLKSIP 234
>SLIT2_MOUSE (Q9R1B9) Slit homolog 2 protein precursor (Slit-2) [Contains: Slit| homolog 2 protein N-product; Slit homolog 2 protein C-product] Length = 1521 Score = 38.9 bits (89), Expect = 0.010 Identities = 32/96 (33%), Positives = 52/96 (54%), Gaps = 2/96 (2%) Frame = +1 Query: 31 LDVRSNQLKSL-PNSIGCLSKLRVLNVSGNLLQSLPATI-EECRALEELNANFNQLTRLP 204 LD+ +NQ+ L P++ L L L + GN + LP ++ E +L+ L N N++ L Sbjct: 329 LDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLR 388 Query: 205 DTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRAL 312 +LH+L LS+ NKL ++ T +ALRA+ Sbjct: 389 VDAFQDLHNLNLLSLYDNKLQTVAKGT--FSALRAI 422 Score = 34.3 bits (77), Expect = 0.26 Identities = 28/102 (27%), Positives = 49/102 (48%), Gaps = 3/102 (2%) Frame = +1 Query: 31 LDVRSNQLKSLPNSIGC-LSKLRVLNVSGNLLQSLPA-TIEECRALEELNANFNQLTRLP 204 L + N L+ P + +KL L++S N +Q++P ++ L ++NQ++ + Sbjct: 108 LRLNRNNLQLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIE 167 Query: 205 DTLGFELHSLRRLSVNSNKLTSLPF-STSHMTALRALDARLN 327 D L L L++N+N +T L S +HM LR N Sbjct: 168 DGAFRALRDLEVLTLNNNNITRLSVASFNHMPKLRTFRLHSN 209 Score = 32.7 bits (73), Expect = 0.75 Identities = 28/108 (25%), Positives = 51/108 (47%), Gaps = 5/108 (4%) Frame = +1 Query: 28 VLDVRSNQLKSLPNSIG-CLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLP 204 ++D R L +P ++ ++++R+ S ++ P + L L+ + NQ++ L Sbjct: 283 IVDCRGKGLTEIPTNLPETITEIRLEQNSIRVIP--PGAFSPYKKLRRLDLSNNQISELA 340 Query: 205 DTLGFELHSLRRLSVNSNKLTSLP---FSTSHMTALRALDA-RLNCIR 336 L SL L + NK+T LP F L L+A ++NC+R Sbjct: 341 PDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLR 388
>SLIT2_RAT (Q9WVC1) Slit homolog 2 protein precursor (Slit-2) (Fragment)| Length = 766 Score = 38.9 bits (89), Expect = 0.010 Identities = 32/96 (33%), Positives = 52/96 (54%), Gaps = 2/96 (2%) Frame = +1 Query: 31 LDVRSNQLKSL-PNSIGCLSKLRVLNVSGNLLQSLPATI-EECRALEELNANFNQLTRLP 204 LD+ +NQ+ L P++ L L L + GN + LP ++ E +L+ L N N++ L Sbjct: 333 LDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLR 392 Query: 205 DTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRAL 312 +LH+L LS+ NKL ++ T +ALRA+ Sbjct: 393 VDAFQDLHNLNLLSLYDNKLQTVAKGT--FSALRAI 426 Score = 34.3 bits (77), Expect = 0.26 Identities = 28/102 (27%), Positives = 49/102 (48%), Gaps = 3/102 (2%) Frame = +1 Query: 31 LDVRSNQLKSLPNSIGC-LSKLRVLNVSGNLLQSLPA-TIEECRALEELNANFNQLTRLP 204 L + N L+ P + +KL L++S N +Q++P ++ L ++NQ++ + Sbjct: 108 LRLNRNNLQLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIE 167 Query: 205 DTLGFELHSLRRLSVNSNKLTSLPF-STSHMTALRALDARLN 327 D L L L++N+N +T L S +HM LR N Sbjct: 168 DGAFRALRDLEVLTLNNNNITRLSVASFNHMPKLRTFRLHSN 209 Score = 32.7 bits (73), Expect = 0.75 Identities = 28/108 (25%), Positives = 51/108 (47%), Gaps = 5/108 (4%) Frame = +1 Query: 28 VLDVRSNQLKSLPNSIG-CLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLP 204 ++D R L +P ++ ++++R+ S ++ P + L L+ + NQ++ L Sbjct: 287 IVDCRGKGLTEIPTNLPETITEIRLEQNSIRVIP--PGAFSPYKKLRRLDLSNNQISELA 344 Query: 205 DTLGFELHSLRRLSVNSNKLTSLP---FSTSHMTALRALDA-RLNCIR 336 L SL L + NK+T LP F L L+A ++NC+R Sbjct: 345 PDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLR 392
>TLR2_MOUSE (Q9QUN7) Toll-like receptor 2 precursor (CD282 antigen)| Length = 784 Score = 38.5 bits (88), Expect = 0.014 Identities = 31/107 (28%), Positives = 50/107 (46%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQL 192 L N+ LD+ N +P+S K+R LN+S ++ + I + LE L+ + N L Sbjct: 412 LKNLTSLDISRNTFHPMPDSCQWPEKMRFLNLSSTGIRVVKTCIPQ--TLEVLDVSNNNL 469 Query: 193 TRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCI 333 D+ L L+ L ++ NKL +LP S L + R N + Sbjct: 470 ----DSFSLFLPRLQELYISRNKLKTLP-DASLFPVLLVMKIRENAV 511
>TLR2_BOVIN (Q95LA9) Toll-like receptor 2 precursor (CD282 antigen)| Length = 784 Score = 38.5 bits (88), Expect = 0.014 Identities = 27/88 (30%), Positives = 44/88 (50%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQL 192 L N+ LD+ N S+P + K++ LN+S + SL + + LE L+ + N L Sbjct: 412 LENLNNLDISKNNFLSMPETCQWPGKMKQLNLSSTRIHSLTQCLPQ--TLEILDVSNNNL 469 Query: 193 TRLPDTLGFELHSLRRLSVNSNKLTSLP 276 D+ L L+ L ++ NKL +LP Sbjct: 470 ----DSFSLILPQLKELYISRNKLKTLP 493
>LRC32_PONPY (Q5RF01) Leucine-rich repeat-containing protein 32 precursor| Length = 662 Score = 38.5 bits (88), Expect = 0.014 Identities = 41/176 (23%), Positives = 70/176 (39%), Gaps = 4/176 (2%) Frame = +1 Query: 31 LDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQL---TRL 201 LD+R N+L P+ + L +L LN+S NL++ ++ + + + ++ L T Sbjct: 248 LDLRENKLLHFPD-LAALPRLIYLNLSNNLIRLPTGPPQDSKGIHAPSEGWSALPLSTPS 306 Query: 202 PDTLGFELHSLRRLSVNSNKLTSLPFS-TSHMTALRALDARLNCIRAXXXXXXXXXXXXX 378 + L L L ++ N++ +P S H+T+L L+ NC+R Sbjct: 307 WNASARPLSQLLNLDLSYNEIELIPDSFLEHLTSLCFLNLSRNCLRTFEARRS------- 359 Query: 379 XXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPL 546 G L L LD+S+N++ L L L GN L Sbjct: 360 -----------------GSLPCLMLLDLSHNALETLELGARALGSLRTLLLQGNAL 398
>LGR8_MOUSE (Q91ZZ5) Relaxin receptor 2 (Leucine-rich repeat-containing| G-protein coupled receptor 8) (G-protein coupled receptor affecting testicular descent) (G-protein coupled receptor 106) Length = 737 Score = 38.5 bits (88), Expect = 0.014 Identities = 28/81 (34%), Positives = 48/81 (59%), Gaps = 3/81 (3%) Frame = +1 Query: 31 LDVRSNQLKSLPNS--IGCLSKLRVLNVSGNLLQSLPA-TIEECRALEELNANFNQLTRL 201 +D+ +N +K + NS + C S L VL + N + +P T + L EL+ + N +T+L Sbjct: 245 VDLANNGIKYITNSTFLTCDS-LTVLFLPRNQIGFVPEKTFSSLKNLGELDLSSNMITKL 303 Query: 202 PDTLGFELHSLRRLSVNSNKL 264 P L +LH L++L+++SN L Sbjct: 304 PVHLFSDLHLLQKLNLSSNPL 324 Score = 37.0 bits (84), Expect = 0.040 Identities = 44/161 (27%), Positives = 69/161 (42%), Gaps = 5/161 (3%) Frame = +1 Query: 82 LSKLRVLNVSGNLLQSL-PATIEECRALEELNANFNQLTRLPDTLGFELHSLRRLSVNSN 258 L L++L +S N + SL P ++ L L + N +TR+ L+SL L + N Sbjct: 167 LHNLQILYLSHNCITSLRPGIFKDLHQLAWLILDDNPITRISQKSFMGLNSLFFLPMVGN 226 Query: 259 KLTSLPFS-TSHMTALRALDARLNCIR--AXXXXXXXXXXXXXXXXSQNFHFLRELPYGL 429 +L +LP + + M L +D N I+ F+ E + Sbjct: 227 RLEALPETLCAQMPQLNWVDLANNGIKYITNSTFLTCDSLTVLFLPRNQIGFVPEKTF-- 284 Query: 430 GLLTSLRELDISYNSISVLPDSM-GCLAKLNKFSAVGNPLI 549 L +L ELD+S N I+ LP + L L K + NPL+ Sbjct: 285 SSLKNLGELDLSSNMITKLPVHLFSDLHLLQKLNLSSNPLL 325
>RP8L1_ARATH (O04093) Putative disease resistance protein RPP8-like protein 1| Length = 821 Score = 38.5 bits (88), Expect = 0.014 Identities = 29/100 (29%), Positives = 47/100 (47%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQL 192 LL V+ L + LP+SIG L LR L++ + LP+++ + L LN FN + Sbjct: 555 LLRVLDLSRVKFEGGKLPSSIGDLIHLRFLSLHRAWISHLPSSLRNLKLLLYLNLGFNGM 614 Query: 193 TRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRAL 312 +P+ L E+ LR L + + S + L +L Sbjct: 615 VHVPNVLK-EMQELRYLQLPMSMHDKTKLELSDLVNLESL 653
>DRL43_ARATH (Q9FKZ0) Probable disease resistance protein At5g66910| Length = 815 Score = 38.5 bits (88), Expect = 0.014 Identities = 40/137 (29%), Positives = 62/137 (45%), Gaps = 5/137 (3%) Frame = +1 Query: 121 LQSLPATIEECRALEELN-ANFNQLTRLPDTLGFELHSLRRLSV----NSNKLTSLPFST 285 L LP I E +L+ L+ N N+L++LP+ +G +L RL V + L+ LP +T Sbjct: 668 LDELPYWIPEVVSLKTLSITNCNKLSQLPEAIG----NLSRLEVLRMCSCMNLSELPEAT 723 Query: 286 SHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDIS 465 ++ LR+LD +C+ LR+LP +G L L + + Sbjct: 724 ERLSNLRSLDIS-HCLG-----------------------LRKLPQEIGKLQKLENISMR 759 Query: 466 YNSISVLPDSMGCLAKL 516 S LPDS+ L L Sbjct: 760 KCSGCELPDSVRYLENL 776
>FMOD_BOVIN (P13605) Fibromodulin precursor (FM) (Collagen-binding 59 kDa| protein) (Keratan sulfate proteoglycan fibromodulin) (KSPG fibromodulin) Length = 375 Score = 38.5 bits (88), Expect = 0.014 Identities = 38/156 (24%), Positives = 72/156 (46%), Gaps = 3/156 (1%) Frame = +1 Query: 37 VRSNQLKSLPNSIGCLSKLRVLN---VSGNLLQSLPATIEECRALEELNANFNQLTRLPD 207 + NQ+ S SKLR L + N L +P+ + R+L EL+ + NQ++R+P+ Sbjct: 135 LHGNQITSDKVGKKVFSKLRHLERLYLDHNNLTRIPSPLP--RSLRELHLDHNQISRVPN 192 Query: 208 TLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXX 387 L +L L ++ N++ + S + +L LD Sbjct: 193 NALEGLENLTALYLHHNEIQEVGSSMKGLRSLILLDL----------------------- 229 Query: 388 SQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDS 495 +++ LR++P GL ++L +L + +N++ +PDS Sbjct: 230 --SYNHLRKVPDGLP--SALEQLYLEHNNVFSVPDS 261
>CHAD_HUMAN (O15335) Chondroadherin precursor (Cartilage leucine-rich protein)| Length = 359 Score = 38.5 bits (88), Expect = 0.014 Identities = 25/93 (26%), Positives = 48/93 (51%), Gaps = 2/93 (2%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSL-PNSIGCLSKLRVLNVSGNLLQSL-PATIEECRALEELNA 177 ++ L+N+ +L + +N+++ L LR L +S N L SL P +++ L + + Sbjct: 143 LSPLVNLFILQLNNNKIRELRAGPFQGAKDLRWLYLSENALSSLQPGALDDVENLAKFHV 202 Query: 178 NFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLP 276 + NQL+ P +L + L ++ N L S+P Sbjct: 203 DRNQLSSYPSAALSKLRVVEELKLSHNPLKSIP 235
>DRL25_ARATH (O50052) Putative disease resistance protein At4g19050| Length = 1181 Score = 38.1 bits (87), Expect = 0.018 Identities = 39/160 (24%), Positives = 72/160 (45%), Gaps = 2/160 (1%) Frame = +1 Query: 49 QLKSLPNSIGCLSKLRVLNVSG--NLLQSLPATIEECRALEELNANFNQLTRLPDTLGFE 222 +LK LP + L+ L++L+ G +L++ L +EE + L L+ + L L DT+ Sbjct: 643 RLKRLPQ-LRPLTNLQILDACGATDLVEMLEVCLEEKKELRILDMSKTSLPELADTIADV 701 Query: 223 LHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFH 402 ++ + L N + + LP S +T L D CI+ Sbjct: 702 VNLNKLLLRNCSLIEELP-SIEKLTHLEVFDVS-GCIK---------------------- 737 Query: 403 FLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNK 522 L+ + G ++ L E+++S ++S LPD + L+ L + Sbjct: 738 -LKNINGSFGEMSYLHEVNLSETNLSELPDKISELSNLKE 776
>FMOD_RAT (P50609) Fibromodulin precursor (FM) (Collagen-binding 59 kDa| protein) (Keratan sulfate proteoglycan fibromodulin) (KSPG fibromodulin) Length = 376 Score = 38.1 bits (87), Expect = 0.018 Identities = 38/156 (24%), Positives = 70/156 (44%), Gaps = 3/156 (1%) Frame = +1 Query: 37 VRSNQLKSLPNSIGCLSKLRVLN---VSGNLLQSLPATIEECRALEELNANFNQLTRLPD 207 + NQ+ S SKLR L + N L +P + R+L EL+ + NQ++R+P+ Sbjct: 136 LHGNQITSDKIGRKVFSKLRHLERLYLDHNNLTRMPGPLP--RSLRELHLDHNQISRVPN 193 Query: 208 TLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXX 387 L +L L ++ N++ + S + +L LD Sbjct: 194 NALEGLENLTALYLHHNEIQEVGSSMRGLRSLILLDL----------------------- 230 Query: 388 SQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDS 495 +++ LR +P GL ++L +L + +N++ +PDS Sbjct: 231 --SYNHLRRVPDGLP--SALEQLYLEHNNVYTVPDS 262 Score = 34.3 bits (77), Expect = 0.26 Identities = 31/107 (28%), Positives = 53/107 (49%), Gaps = 2/107 (1%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQL 192 L N+ L + N+++ + +S+ L L +L++S N L+ +P + ALE+L N + Sbjct: 199 LENLTALYLHHNEIQEVGSSMRGLRSLILLDLSYNHLRRVPDGLPS--ALEQLYLEHNNV 256 Query: 193 TRLPDTL--GFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLN 327 +PD+ G RLS NS L +T + ++L LD N Sbjct: 257 YTVPDSYFRGSPKLLYVRLSHNSLTNNGLATNTFNSSSLLELDLSYN 303
>FMOD_MOUSE (P50608) Fibromodulin precursor (FM) (Collagen-binding 59 kDa| protein) (Keratan sulfate proteoglycan fibromodulin) (KSPG fibromodulin) Length = 376 Score = 38.1 bits (87), Expect = 0.018 Identities = 38/156 (24%), Positives = 70/156 (44%), Gaps = 3/156 (1%) Frame = +1 Query: 37 VRSNQLKSLPNSIGCLSKLRVLN---VSGNLLQSLPATIEECRALEELNANFNQLTRLPD 207 + NQ+ S SKLR L + N L +P + R+L EL+ + NQ++R+P+ Sbjct: 136 LHGNQITSDKVGRKVFSKLRHLERLYLDHNNLTRMPGPLP--RSLRELHLDHNQISRVPN 193 Query: 208 TLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXX 387 L +L L ++ N++ + S + +L LD Sbjct: 194 NALEGLENLTALYLHHNEIQEVGSSMRGLRSLILLDL----------------------- 230 Query: 388 SQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDS 495 +++ LR +P GL ++L +L + +N++ +PDS Sbjct: 231 --SYNHLRRVPDGLP--SALEQLYLEHNNVYTVPDS 262 Score = 34.3 bits (77), Expect = 0.26 Identities = 31/107 (28%), Positives = 53/107 (49%), Gaps = 2/107 (1%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQL 192 L N+ L + N+++ + +S+ L L +L++S N L+ +P + ALE+L N + Sbjct: 199 LENLTALYLHHNEIQEVGSSMRGLRSLILLDLSYNHLRRVPDGLPS--ALEQLYLEHNNV 256 Query: 193 TRLPDTL--GFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLN 327 +PD+ G RLS NS L +T + ++L LD N Sbjct: 257 YTVPDSYFRGSPKLLYVRLSHNSLTNNGLATNTFNSSSLLELDLSYN 303
>FMOD_HUMAN (Q06828) Fibromodulin precursor (FM) (Collagen-binding 59 kDa| protein) (Keratan sulfate proteoglycan fibromodulin) (KSPG fibromodulin) Length = 376 Score = 38.1 bits (87), Expect = 0.018 Identities = 38/156 (24%), Positives = 70/156 (44%), Gaps = 3/156 (1%) Frame = +1 Query: 37 VRSNQLKSLPNSIGCLSKLRVLN---VSGNLLQSLPATIEECRALEELNANFNQLTRLPD 207 + NQ+ S SKLR L + N L +P + R+L EL+ + NQ++R+P+ Sbjct: 136 LHGNQITSDKVGRKVFSKLRHLERLYLDHNNLTRMPGPLP--RSLRELHLDHNQISRVPN 193 Query: 208 TLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXX 387 L +L L + N++ + S + +L LD Sbjct: 194 NALEGLENLTALYLQHNEIQEVGSSMRGLRSLYLLDL----------------------- 230 Query: 388 SQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDS 495 +++ LR++P GL ++L +L + +N++ +PDS Sbjct: 231 --SYNHLRKVPDGLP--SALEQLYMEHNNVYTVPDS 262
>CHAD_BOVIN (Q27972) Chondroadherin precursor (Cartilage leucine-rich protein)| (38 kDa bone protein) [Contains: Chondroadherin minor form] Length = 361 Score = 37.7 bits (86), Expect = 0.023 Identities = 26/93 (27%), Positives = 50/93 (53%), Gaps = 2/93 (2%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSK-LRVLNVSGNLLQSL-PATIEECRALEELNA 177 ++ L+N+ +L + +N+++ L + +K LR L +S N L SL P +++ L + Sbjct: 145 LSPLVNLFILQLNNNKIRELRSGAFQGAKDLRWLYLSENSLSSLQPGALDDVENLAKFYL 204 Query: 178 NFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLP 276 + NQL+ P +L + L ++ N L S+P Sbjct: 205 DRNQLSSYPSAALSKLRVVEELKLSHNPLKSIP 237
>SLIK4_MOUSE (Q810B8) SLIT and NTRK-like protein 4 precursor| Length = 837 Score = 37.7 bits (86), Expect = 0.023 Identities = 40/155 (25%), Positives = 65/155 (41%), Gaps = 4/155 (2%) Frame = +1 Query: 100 LNVSGNLLQSLPAT-IEECRALEELNANFNQLTRLPDTLGFELHSLRRLSVNSNKLTSL- 273 L+V+GN ++ + + E L+ L+ NQ+T + + L +LRRL +N N++ L Sbjct: 382 LHVNGNNIKDVDISDFTEFEGLDLLHLGSNQITLIKGEVFHNLTNLRRLYLNGNQIERLY 441 Query: 274 PFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRE 453 P S + L+ L N I+ N + L+ LP + L Sbjct: 442 PEIFSGLHNLQYLYLEYNLIKEILAGTFDSMPNLQLLYLNN-NLLKSLPVYIFSGAPLAR 500 Query: 454 LDISYNSISVLPDS--MGCLAKLNKFSAVGNPLIC 552 L++ N LP S + L L + GNP C Sbjct: 501 LNLRNNKFMYLPVSGVLDQLQSLTQIDLEGNPWDC 535 Score = 37.7 bits (86), Expect = 0.023 Identities = 32/108 (29%), Positives = 56/108 (51%), Gaps = 2/108 (1%) Frame = +1 Query: 19 NVVVLDVRSNQLKSLPNSIGC-LSKLRVLNVSGNLLQSLPA-TIEECRALEELNANFNQL 192 + V L + +N+L+++ LS L+ L+++ N L+ L A T LE L A++N + Sbjct: 84 HAVSLHLGNNKLQNIEGGAFLGLSALKQLHLNNNELKILRADTFLGIENLEYLQADYNLI 143 Query: 193 TRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIR 336 + +LH L+ L +N N ++ LP + +L LD R N I+ Sbjct: 144 KYIERGAFNKLHKLKVLILNDNLISFLPDNIFRFASLTHLDIRGNRIQ 191 Score = 30.8 bits (68), Expect = 2.9 Identities = 25/84 (29%), Positives = 41/84 (48%), Gaps = 2/84 (2%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKS-LPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQ 189 L N+ L + N +K L + + L++L ++ NLL+SLP I L LN N+ Sbjct: 448 LHNLQYLYLEYNLIKEILAGTFDSMPNLQLLYLNNNLLKSLPVYIFSGAPLARLNLRNNK 507 Query: 190 LTRLP-DTLGFELHSLRRLSVNSN 258 LP + +L SL ++ + N Sbjct: 508 FMYLPVSGVLDQLQSLTQIDLEGN 531
>SLIK4_HUMAN (Q8IW52) SLIT and NTRK-like protein 4 precursor| Length = 837 Score = 37.7 bits (86), Expect = 0.023 Identities = 41/178 (23%), Positives = 74/178 (41%), Gaps = 4/178 (2%) Frame = +1 Query: 31 LDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPAT-IEECRALEELNANFNQLTRLPD 207 ++ + ++S+ I + L+V+GN ++ + + + L+ L+ NQ+T + Sbjct: 359 VNCQEKNIQSMSELIPKPLNAKKLHVNGNSIKDVDVSDFTDFEGLDLLHLGSNQITVIKG 418 Query: 208 TLGFELHSLRRLSVNSNKLTSL-PFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXX 384 + L +LRRL +N N++ L P S + L+ L N I+ Sbjct: 419 DVFHNLTNLRRLYLNGNQIERLYPEIFSGLHNLQYLYLEYNLIKEISAGTFDSMPNLQLL 478 Query: 385 XSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDS--MGCLAKLNKFSAVGNPLIC 552 N + L+ LP + L L++ N LP S + L L + GNP C Sbjct: 479 YLNN-NLLKSLPVYIFSGAPLARLNLRNNKFMYLPVSGVLDQLQSLTQIDLEGNPWDC 535 Score = 37.7 bits (86), Expect = 0.023 Identities = 32/108 (29%), Positives = 56/108 (51%), Gaps = 2/108 (1%) Frame = +1 Query: 19 NVVVLDVRSNQLKSLPNSIGC-LSKLRVLNVSGNLLQSLPA-TIEECRALEELNANFNQL 192 + V L + +N+L+++ LS L+ L+++ N L+ L A T LE L A++N + Sbjct: 84 HAVSLHLGNNKLQNIEGGAFLGLSALKQLHLNNNELKILRADTFLGIENLEYLQADYNLI 143 Query: 193 TRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIR 336 + +LH L+ L +N N ++ LP + +L LD R N I+ Sbjct: 144 KYIERGAFNKLHKLKVLILNDNLISFLPDNIFRFASLTHLDIRGNRIQ 191 Score = 30.4 bits (67), Expect = 3.7 Identities = 22/79 (27%), Positives = 39/79 (49%), Gaps = 1/79 (1%) Frame = +1 Query: 25 VVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLP 204 ++ ++ + S+PN L++L ++ NLL+SLP I L LN N+ LP Sbjct: 460 LIKEISAGTFDSMPN-------LQLLYLNNNLLKSLPVYIFSGAPLARLNLRNNKFMYLP 512 Query: 205 -DTLGFELHSLRRLSVNSN 258 + +L SL ++ + N Sbjct: 513 VSGVLDQLQSLTQIDLEGN 531
>R13L2_ARATH (Q9STE5) Putative disease resistance RPP13-like protein 2| Length = 847 Score = 37.7 bits (86), Expect = 0.023 Identities = 24/63 (38%), Positives = 35/63 (55%) Frame = +1 Query: 58 SLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDTLGFELHSLR 237 SLP+ IG L LR L ++ ++ +LP I R L+ L+A+ N R+ D L SLR Sbjct: 579 SLPDVIGGLVHLRYLGIADTVVNNLPDFISNLRFLQTLDASGNSFERMTDL--SNLTSLR 636 Query: 238 RLS 246 L+ Sbjct: 637 HLT 639
>LRC33_BOVIN (Q3ZBI5) Leucine-rich repeat-containing protein 33 precursor| Length = 692 Score = 37.4 bits (85), Expect = 0.031 Identities = 46/182 (25%), Positives = 70/182 (38%), Gaps = 19/182 (10%) Frame = +1 Query: 22 VVVLDVRSNQLKSL---PNSIGCLSKLRVLNVSGNLLQSLPATI-EECRALEELNANFNQ 189 +V LD+ NQL L P GCL L+ N+S N L +PA + R L ++ + NQ Sbjct: 378 LVELDLSQNQLSELHLAPGLPGCLRSLQSFNLSSNQLLGVPAGLFANARNLATVDMSHNQ 437 Query: 190 LTRLPDTLGFE------------LHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLN-- 327 ++ P + + SL+ LS+ L +L + TAL LD N Sbjct: 438 ISLCPLPASLDPGGTPGCVDFRNVASLQSLSLEDCGLEALQDCSFQGTALTHLDLSGNWG 497 Query: 328 CIRAXXXXXXXXXXXXXXXXSQNFHFLREL-PYGLGLLTSLRELDISYNSISVLPDSMGC 504 + +N +LR LD+S N+++ P G Sbjct: 498 VLNGSIAPLWDVAPTLQVLSLRNVGLTSSFTELDFSAFENLRSLDLSGNALTSFPRFGGS 557 Query: 505 LA 510 LA Sbjct: 558 LA 559
>LRC15_MOUSE (Q80X72) Leucine-rich repeat-containing protein 15 precursor| Length = 579 Score = 37.4 bits (85), Expect = 0.031 Identities = 30/114 (26%), Positives = 53/114 (46%), Gaps = 6/114 (5%) Frame = +1 Query: 7 ARLLNVVVLDVRSNQLKSL-PNSIGCLSKLRVLNVSGNLLQSLPATIEECRA-LEELNAN 180 + L + VL + NQL + P + L+ LR L++ N LQ L + A L ++ Sbjct: 314 SHLNQLQVLILSHNQLSYISPGAFNGLTNLRELSLHTNALQDLDGNVFRSLANLRNVSLQ 373 Query: 181 FNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFS----TSHMTALRALDARLNC 330 N+L +LP ++ ++ L + + +N L +LP ++ LR D C Sbjct: 374 NNRLRQLPGSIFANVNGLMTIQLQNNNLENLPLGIFDHLGNLCELRLYDNPWRC 427
>BRL3_ARATH (Q9LJF3) Serine/threonine-protein kinase BRI1-like 3 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 3) Length = 1164 Score = 37.4 bits (85), Expect = 0.031 Identities = 46/193 (23%), Positives = 81/193 (41%), Gaps = 32/193 (16%) Frame = +1 Query: 19 NVVVLDVRSNQLKS-LPN---SIGCLSKLRVLNVSGNLLQ-SLPATIEECRALEELNANF 183 N+ VLD+ SN+ +P+ S+ S L L ++ N L ++P + +C++L+ ++ +F Sbjct: 376 NLRVLDLSSNEFTGEVPSGFCSLQSSSVLEKLLIANNYLSGTVPVELGKCKSLKTIDLSF 435 Query: 184 NQLTRL-------------------------PDTLGFELHSLRRLSVNSNKLT-SLPFST 285 N LT L P+++ + +L L +N+N LT SLP S Sbjct: 436 NALTGLIPKEIWTLPKLSDLVMWANNLTGGIPESICVDGGNLETLILNNNLLTGSLPESI 495 Query: 286 SHMTALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDIS 465 S T + + N + E+P G+G L L L + Sbjct: 496 SKCTNMLWISLSSNLLTG------------------------EIPVGIGKLEKLAILQLG 531 Query: 466 YNSIS-VLPDSMG 501 NS++ +P +G Sbjct: 532 NNSLTGNIPSELG 544 Score = 37.0 bits (84), Expect = 0.040 Identities = 31/91 (34%), Positives = 51/91 (56%), Gaps = 4/91 (4%) Frame = +1 Query: 19 NVVVLDVRSNQLK-SLPNSIGCLSKLRVLNVSGNLLQ-SLPATIEECRALEELNANFNQL 192 +++ LD+ N + S+P G + L+VLN+ NLL ++P + +A+ L+ + N L Sbjct: 640 SMIYLDLSYNAVSGSIPLGYGAMGYLQVLNLGHNLLTGTIPDSFGGLKAIGVLDLSHNDL 699 Query: 193 TR-LPDTLGFELHSLRRLSVNSNKLTS-LPF 279 LP +LG L L L V++N LT +PF Sbjct: 700 QGFLPGSLG-GLSFLSDLDVSNNNLTGPIPF 729
>SLIK1_PONPY (Q5RAC4) SLIT and NTRK-like protein 1 precursor| Length = 696 Score = 37.4 bits (85), Expect = 0.031 Identities = 23/67 (34%), Positives = 38/67 (56%), Gaps = 1/67 (1%) Frame = +1 Query: 7 ARLLNVVVLDVRSNQLKS-LPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 A L N+ L+V N ++ LP + + KLR+L ++ NLL+SLP + +L +L+ + Sbjct: 444 AGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILNNNLLRSLPVDVFAGVSLSKLSLHN 503 Query: 184 NQLTRLP 204 N LP Sbjct: 504 NYFMYLP 510 Score = 36.2 bits (82), Expect = 0.068 Identities = 30/112 (26%), Positives = 53/112 (47%), Gaps = 2/112 (1%) Frame = +1 Query: 7 ARLLNVVVLDVRSNQLKSL-PNSIGCLSKLRVLNVSGNLLQSL-PATIEECRALEELNAN 180 A N V L + +N L + P + L ++ L+++ N ++S T LE L A+ Sbjct: 79 ANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSFRKQTFLGLDDLEYLQAD 138 Query: 181 FNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIR 336 FN L + +L+ L L +N N +++LP + + LD R N ++ Sbjct: 139 FNLLRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYVPITHLDLRGNRLK 190 Score = 33.9 bits (76), Expect = 0.34 Identities = 32/106 (30%), Positives = 50/106 (47%), Gaps = 3/106 (2%) Frame = +1 Query: 19 NVVVLDVRSNQLKSLPNS-IGCLSKLRVLNVSGNLLQSLPAT-IEECRALEELNANFNQL 192 N+++LD+ +N + ++ N+ L LR L + N L +L + LE LN +N + Sbjct: 400 NLILLDLGNNNIATVENNTFKNLLDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEYNAI 459 Query: 193 TR-LPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLN 327 LP T + LR L +N+N L SLP +L L N Sbjct: 460 QLILPGTFN-AMPKLRILILNNNLLRSLPVDVFAGVSLSKLSLHNN 504 Score = 31.2 bits (69), Expect = 2.2 Identities = 16/47 (34%), Positives = 27/47 (57%) Frame = +1 Query: 64 PNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLP 204 P + L+KL VL ++ NL+ +LPA + + + L+ N+L LP Sbjct: 147 PGAFQDLNKLEVLILNDNLISTLPANVFQYVPITHLDLRGNRLKTLP 193
>SLIK1_MOUSE (Q810C1) SLIT and NTRK-like protein 1 precursor| Length = 696 Score = 37.4 bits (85), Expect = 0.031 Identities = 23/67 (34%), Positives = 38/67 (56%), Gaps = 1/67 (1%) Frame = +1 Query: 7 ARLLNVVVLDVRSNQLKS-LPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 A L N+ L+V N ++ LP + + KLR+L ++ NLL+SLP + +L +L+ + Sbjct: 444 AGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILNNNLLRSLPVDVFAGVSLSKLSLHN 503 Query: 184 NQLTRLP 204 N LP Sbjct: 504 NYFMYLP 510 Score = 36.2 bits (82), Expect = 0.068 Identities = 30/112 (26%), Positives = 53/112 (47%), Gaps = 2/112 (1%) Frame = +1 Query: 7 ARLLNVVVLDVRSNQLKSL-PNSIGCLSKLRVLNVSGNLLQSL-PATIEECRALEELNAN 180 A N V L + +N L + P + L ++ L+++ N ++S T LE L A+ Sbjct: 79 ANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSFRKQTFLGLDDLEYLQAD 138 Query: 181 FNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIR 336 FN L + +L+ L L +N N +++LP + + LD R N ++ Sbjct: 139 FNLLRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYVPITHLDLRGNRLK 190 Score = 34.3 bits (77), Expect = 0.26 Identities = 32/106 (30%), Positives = 50/106 (47%), Gaps = 3/106 (2%) Frame = +1 Query: 19 NVVVLDVRSNQLKSLPNS-IGCLSKLRVLNVSGNLLQSLPAT-IEECRALEELNANFNQL 192 N+++LD+ +N + ++ N+ L LR L + N L +L + LE LN +N + Sbjct: 400 NLILLDLGNNNIANIENNTFKNLLDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEYNAI 459 Query: 193 TR-LPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLN 327 LP T + LR L +N+N L SLP +L L N Sbjct: 460 QLILPGTFN-AMPKLRILILNNNLLRSLPVDVFAGVSLSKLSLHNN 504 Score = 31.2 bits (69), Expect = 2.2 Identities = 16/47 (34%), Positives = 27/47 (57%) Frame = +1 Query: 64 PNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLP 204 P + L+KL VL ++ NL+ +LPA + + + L+ N+L LP Sbjct: 147 PGAFQDLNKLEVLILNDNLISTLPANVFQYVPITHLDLRGNRLKTLP 193
>SLIK1_HUMAN (Q96PX8) SLIT and NTRK-like protein 1 precursor (Leucine-rich| repeat-containing protein 12) Length = 696 Score = 37.4 bits (85), Expect = 0.031 Identities = 23/67 (34%), Positives = 38/67 (56%), Gaps = 1/67 (1%) Frame = +1 Query: 7 ARLLNVVVLDVRSNQLKS-LPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 A L N+ L+V N ++ LP + + KLR+L ++ NLL+SLP + +L +L+ + Sbjct: 444 AGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILNNNLLRSLPVDVFAGVSLSKLSLHN 503 Query: 184 NQLTRLP 204 N LP Sbjct: 504 NYFMYLP 510 Score = 36.2 bits (82), Expect = 0.068 Identities = 30/112 (26%), Positives = 53/112 (47%), Gaps = 2/112 (1%) Frame = +1 Query: 7 ARLLNVVVLDVRSNQLKSL-PNSIGCLSKLRVLNVSGNLLQSL-PATIEECRALEELNAN 180 A N V L + +N L + P + L ++ L+++ N ++S T LE L A+ Sbjct: 79 ANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSFRKQTFLGLDDLEYLQAD 138 Query: 181 FNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIR 336 FN L + +L+ L L +N N +++LP + + LD R N ++ Sbjct: 139 FNLLRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYVPITHLDLRGNRLK 190 Score = 33.9 bits (76), Expect = 0.34 Identities = 32/106 (30%), Positives = 50/106 (47%), Gaps = 3/106 (2%) Frame = +1 Query: 19 NVVVLDVRSNQLKSLPNS-IGCLSKLRVLNVSGNLLQSLPAT-IEECRALEELNANFNQL 192 N+++LD+ +N + ++ N+ L LR L + N L +L + LE LN +N + Sbjct: 400 NLILLDLGNNNIATVENNTFKNLLDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEYNAI 459 Query: 193 TR-LPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLN 327 LP T + LR L +N+N L SLP +L L N Sbjct: 460 QLILPGTFN-AMPKLRILILNNNLLRSLPVDVFAGVSLSKLSLHNN 504 Score = 31.2 bits (69), Expect = 2.2 Identities = 16/47 (34%), Positives = 27/47 (57%) Frame = +1 Query: 64 PNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLP 204 P + L+KL VL ++ NL+ +LPA + + + L+ N+L LP Sbjct: 147 PGAFQDLNKLEVLILNDNLISTLPANVFQYVPITHLDLRGNRLKTLP 193
>TLR4_CRIGR (Q9WV82) Toll-like receptor 4 precursor (CD284 antigen)| Length = 838 Score = 37.4 bits (85), Expect = 0.031 Identities = 29/81 (35%), Positives = 44/81 (54%), Gaps = 2/81 (2%) Frame = +1 Query: 1 GIARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQS--LPATIEECRALEELN 174 G+A L N+V ++++ L SLP IG L L+ LNV+ NL+ S LP LE L+ Sbjct: 123 GLANLQNLVAVEIKLASLDSLP--IGHLVTLKKLNVAHNLIHSFKLPEYFSNLTNLEHLD 180 Query: 175 ANFNQLTRLPDTLGFELHSLR 237 + N + + T +L +LR Sbjct: 181 LSNNYIQTIYYT---DLQTLR 198
>DRL37_ARATH (Q9LVT4) Probable disease resistance protein At5g47250| Length = 843 Score = 37.4 bits (85), Expect = 0.031 Identities = 21/43 (48%), Positives = 28/43 (65%) Frame = +1 Query: 388 SQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKL 516 S NF + ELP G+ L SLR L++S SI LP+ +G L+KL Sbjct: 566 SWNFQ-ITELPKGISALVSLRLLNLSGTSIKHLPEGLGVLSKL 607
>LRC27_HUMAN (Q9C0I9) Leucine-rich repeat-containing protein 27| Length = 530 Score = 37.4 bits (85), Expect = 0.031 Identities = 19/54 (35%), Positives = 31/54 (57%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELN 174 L N+ LD+R N++K+LP+ IG L+ L + N ++ LP + L+ LN Sbjct: 90 LPNLTWLDLRYNRIKALPSGIGAHQHLKTLLLERNPIKMLPVELGSVTTLKALN 143 Score = 32.7 bits (73), Expect = 0.75 Identities = 35/136 (25%), Positives = 55/136 (40%), Gaps = 1/136 (0%) Frame = +1 Query: 169 LNANFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTA-LRALDARLNCIRAXX 345 L+ + + L RL + F + SL++L + N L +P + L LD R N I+A Sbjct: 50 LDLSESGLCRLEEV--FRIPSLQQLHLQRNALCVIPQDFFQLLPNLTWLDLRYNRIKA-- 105 Query: 346 XXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKF 525 LP G+G L+ L + N I +LP +G + L Sbjct: 106 -----------------------LPSGIGAHQHLKTLLLERNPIKMLPVELGSVTTLKAL 142 Query: 526 SAVGNPLICPPMDIVE 573 + PL PP +V+ Sbjct: 143 NLRHCPLEFPPQLVVQ 158
>SLIK6_MOUSE (Q8C110) SLIT and NTRK-like protein 6 precursor| Length = 840 Score = 37.0 bits (84), Expect = 0.040 Identities = 21/48 (43%), Positives = 27/48 (56%) Frame = +1 Query: 61 LPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLP 204 LP + + KL+VL ++ NLLQ LPA I L +N NQ T LP Sbjct: 450 LPGTFNPMPKLKVLYLNNNLLQVLPAHIFLGIPLTRVNLKTNQFTHLP 497 Score = 33.1 bits (74), Expect = 0.58 Identities = 26/87 (29%), Positives = 42/87 (48%) Frame = +1 Query: 67 NSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDTLGFELHSLRRLS 246 N +G L +L + + S +L+ T LE L A+ N +T + + +L+ L+ L Sbjct: 109 NGLGLLKQLHINHNSLEILKE--DTFHGLENLEFLQADNNFITIIEPSAFSKLNRLKVLI 166 Query: 247 VNSNKLTSLPFSTSHMTALRALDARLN 327 +N N + SLP + L LD R N Sbjct: 167 LNDNAIESLPPNIFRFVPLTHLDLRGN 193 Score = 32.7 bits (73), Expect = 0.75 Identities = 22/62 (35%), Positives = 34/62 (54%) Frame = +1 Query: 64 PNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDTLGFELHSLRRL 243 P++ L++L+VL ++ N ++SLP I L L+ NQL LP +GF H R L Sbjct: 153 PSAFSKLNRLKVLILNDNAIESLPPNIFRFVPLTHLDLRGNQLQTLP-YVGFLEHIGRIL 211 Query: 244 SV 249 + Sbjct: 212 DL 213
>OMD_HUMAN (Q99983) Osteomodulin precursor (Osteoadherin) (OSAD) (Keratan| sulfate proteoglycan osteomodulin) (KSPG osteomodulin) Length = 421 Score = 37.0 bits (84), Expect = 0.040 Identities = 29/111 (26%), Positives = 56/111 (50%), Gaps = 3/111 (2%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKS--LPNSIGC-LSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 L+N+ +LD+ N L L + I + KL LN+ N L+S+P + +L L+ Sbjct: 185 LVNLTMLDLCYNYLHDSLLKDKIFAKMEKLMQLNLCSNRLESMPPGLPS--SLMYLSLEN 242 Query: 184 NQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIR 336 N ++ +P+ +L L L ++ NKL +P++ ++ + L N ++ Sbjct: 243 NSISSIPEKYFDKLPKLHTLRMSHNKLQDIPYNIFNLPNIVELSVGHNKLK 293
>YOPM_YERPE (P17778) Outer membrane protein yopM| Length = 409 Score = 37.0 bits (84), Expect = 0.040 Identities = 33/102 (32%), Positives = 46/102 (45%) Frame = +1 Query: 19 NVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTR 198 N+ L+ SN+++SL L LNVS N L LPA LE L A+FN L Sbjct: 298 NLYYLNASSNEIRSL---CDLPPSLEELNVSNNKLIELPALPPR---LERLIASFNHLAE 351 Query: 199 LPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARL 324 +P+ +L++L V N L P + LR R+ Sbjct: 352 VPEL----PQNLKQLHVEYNPLREFPDIPESVEDLRMNSERV 389 Score = 31.6 bits (70), Expect = 1.7 Identities = 27/90 (30%), Positives = 43/90 (47%), Gaps = 3/90 (3%) Frame = +1 Query: 28 VLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPD 207 ++DV +N LK LP+ L + N L+ LP ++ L + A+ N L +LPD Sbjct: 157 IIDVDNNSLKKLPD---LPPSLEFIAAGNNQLEELP-ELQNLPFLTAIYADNNSLKKLPD 212 Query: 208 TLGFELHSL---RRLSVNSNKLTSLPFSTS 288 L L S+ + +L +LPF T+ Sbjct: 213 -LPLSLESIVAGNNILEELPELQNLPFLTT 241
>LUM_RAT (P51886) Lumican precursor (Keratan sulfate proteoglycan lumican)| (KSPG lumican) Length = 338 Score = 37.0 bits (84), Expect = 0.040 Identities = 40/156 (25%), Positives = 74/156 (47%), Gaps = 3/156 (1%) Frame = +1 Query: 31 LDVRSNQLKSLPNSIGCLSKLRVLNVSGNLL--QSLPATIEECRALEELNANFNQLTRLP 204 L + +N++ L + G L L + + N L +++ A+++ ++LE L+ +FNQ+++LP Sbjct: 142 LQLANNKISKLGSFDG-LVNLTFIYLQHNQLKEEAVSASLKGLKSLEYLDLSFNQMSKLP 200 Query: 205 DTLGFELHSLRRLSVNSNKLTSLPFS-TSHMTALRALDARLNCIRAXXXXXXXXXXXXXX 381 L SL L +++NK+T++P + T L+ L Sbjct: 201 AGLP---TSLLTLYLDNNKITNIPDEYFNRFTGLQYL----------------------- 234 Query: 382 XXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLP 489 S N +P ++SL ELD+SYN + +P Sbjct: 235 RLSHNELADSGVPGNSFNISSLLELDLSYNKLKSIP 270 Score = 33.9 bits (76), Expect = 0.34 Identities = 38/158 (24%), Positives = 75/158 (47%), Gaps = 4/158 (2%) Frame = +1 Query: 31 LDVRSNQLKSLPN-SIGCLSKLRVLNVSGNLLQSLPA---TIEECRALEELNANFNQLTR 198 L +R+NQ+ + + ++ L+ L + NLL++ + + L++L+ N+N LT Sbjct: 71 LYLRNNQIDHIDEKAFENVTDLQWLILDHNLLENSKIKGKVFSKLKQLKKLHINYNNLT- 129 Query: 199 LPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXX 378 +++G SL+ L + +NK++ L S + L + + N ++ Sbjct: 130 --ESVGPLPKSLQDLQLANNKISKLG-SFDGLVNLTFIYLQHNQLKEEAVSASLKGLKSL 186 Query: 379 XXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPD 492 +F+ + +LP GL TSL L + N I+ +PD Sbjct: 187 EYLDLSFNQMSKLPAGLP--TSLLTLYLDNNKITNIPD 222 Score = 32.7 bits (73), Expect = 0.75 Identities = 30/115 (26%), Positives = 51/115 (44%), Gaps = 27/115 (23%) Frame = +1 Query: 13 LLNVVVLDVRSNQLK--SLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFN 186 L+N+ + ++ NQLK ++ S+ L L L++S N + LPA + +L L + N Sbjct: 158 LVNLTFIYLQHNQLKEEAVSASLKGLKSLEYLDLSFNQMSKLPAGLPT--SLLTLYLDNN 215 Query: 187 QLTRLPDTL-------------------------GFELHSLRRLSVNSNKLTSLP 276 ++T +PD F + SL L ++ NKL S+P Sbjct: 216 KITNIPDEYFNRFTGLQYLRLSHNELADSGVPGNSFNISSLLELDLSYNKLKSIP 270
>SLIT3_RAT (O88280) Slit homolog 3 protein precursor (Slit-3) (Multiple| epidermal growth factor-like domains 5) Length = 1523 Score = 37.0 bits (84), Expect = 0.040 Identities = 28/105 (26%), Positives = 53/105 (50%), Gaps = 2/105 (1%) Frame = +1 Query: 19 NVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPA-TIEECRALEELNANFNQLT 195 +V L + N L ++P + +L ++++S N + L T L L ++N+L Sbjct: 753 DVTELYLEGNHLTAVPKELSTFRQLTLIDLSNNSISMLTNHTFSNMSHLSTLILSYNRLR 812 Query: 196 RLPDTLGFELHSLRRLSVNSNKLTSLP-FSTSHMTALRALDARLN 327 +P L SLR L+++ N ++S+P S + +T+L L +N Sbjct: 813 CIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGIN 857 Score = 30.0 bits (66), Expect = 4.9 Identities = 26/108 (24%), Positives = 53/108 (49%), Gaps = 5/108 (4%) Frame = +1 Query: 28 VLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPA-TIEECRALEELNANFNQLTRLP 204 ++D R L +P ++ + + + N ++S+PA + + L+ ++ + NQ++ + Sbjct: 290 IVDCRGKGLTEIPANLP--EGIVEIRLEQNSIKSIPAGAFIQYKKLKRIDISKNQISDIA 347 Query: 205 DTLGFELHSLRRLSVNSNKLTSLP---FSTSHMTALRALDA-RLNCIR 336 L SL L + NK+T +P F L L+A ++NC+R Sbjct: 348 PDAFQGLKSLTSLVLYGNKITEIPKGLFDGLVSLQLLLLNANKINCLR 395
>SLIT3_HUMAN (O75094) Slit homolog 3 protein precursor (Slit-3) (Multiple| epidermal growth factor-like domains 5) Length = 1523 Score = 37.0 bits (84), Expect = 0.040 Identities = 24/87 (27%), Positives = 44/87 (50%), Gaps = 1/87 (1%) Frame = +1 Query: 19 NVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPA-TIEECRALEELNANFNQLT 195 +V L + N L ++P + L L ++++S N + L T L L ++N+L Sbjct: 753 DVTELYLEGNHLTAVPRELSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNRLR 812 Query: 196 RLPDTLGFELHSLRRLSVNSNKLTSLP 276 +P L SLR L+++ N ++S+P Sbjct: 813 CIPVHAFNGLRSLRVLTLHGNDISSVP 839
>LRC33_HUMAN (Q86YC3) Leucine-rich repeat-containing protein 33 precursor| Length = 692 Score = 36.6 bits (83), Expect = 0.052 Identities = 57/201 (28%), Positives = 75/201 (37%), Gaps = 42/201 (20%) Frame = +1 Query: 82 LSKLRVLNVSGNLLQSLPATIEECR-ALEELNANFNQLTRLPDTLGFELHSLRRLSVNSN 258 L++LRVLNVS N+L+ AT E LE L+ + NQL P L + LR L + N Sbjct: 225 LTRLRVLNVSYNVLEWFLATGGEAAFELETLDLSHNQLLFFP--LLPQYSKLRTLLLRDN 282 Query: 259 KL--------TSLP-------------------------FSTSHMTALRALDARLNCIRA 339 + TS P FS+S + LR LD N + Sbjct: 283 NMGFYRDLYNTSSPREMVAQFLLVDGNVTNITTVSLWEEFSSSDLADLRFLDMSQNQFQY 342 Query: 340 XXXXXXXXX-XXXXXXXSQN----FHFLRELPYGLGLLTSLRELDISYNSISVL---PDS 495 QN H P G +L ELD+S+N +S L P Sbjct: 343 LPDGFLRKMPSLSHLNLHQNCLMTLHIREHEPPG-----ALTELDLSHNQLSELHLAPGL 397 Query: 496 MGCLAKLNKFSAVGNPLICPP 558 CL L F+ N L+ P Sbjct: 398 ASCLGSLRLFNLSSNQLLGVP 418
>NUD1_YEAST (P32336) Protein NUD1| Length = 851 Score = 36.6 bits (83), Expect = 0.052 Identities = 22/85 (25%), Positives = 45/85 (52%) Frame = +1 Query: 19 NVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTR 198 NVV L +N++ S S+ L L++S NLL + + C L+E+N ++N + Sbjct: 521 NVVQLFCSNNKITSAHCSLAGFHDLECLDLSYNLLNTSLKFLSLCHHLQEVNLSYNSIQS 580 Query: 199 LPDTLGFELHSLRRLSVNSNKLTSL 273 L G +++L++++N++ + Sbjct: 581 LE---GIGSSRMKKLNLSNNEINGI 602 Score = 33.9 bits (76), Expect = 0.34 Identities = 18/39 (46%), Positives = 27/39 (69%) Frame = +1 Query: 16 LNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSL 132 L V VLD+ +N + + N I CL +L+VLN++GN L S+ Sbjct: 620 LTVEVLDLSNNNIIGVRN-INCLPRLKVLNLNGNPLVSI 657
>SLIT2_HUMAN (O94813) Slit homolog 2 protein precursor (Slit-2) [Contains: Slit| homolog 2 protein N-product; Slit homolog 2 protein C-product] Length = 1529 Score = 36.6 bits (83), Expect = 0.052 Identities = 30/96 (31%), Positives = 51/96 (53%), Gaps = 2/96 (2%) Frame = +1 Query: 31 LDVRSNQLKSL-PNSIGCLSKLRVLNVSGNLLQSLPATI-EECRALEELNANFNQLTRLP 204 +D+ +NQ+ L P++ L L L + GN + LP ++ E +L+ L N N++ L Sbjct: 329 IDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLR 388 Query: 205 DTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRAL 312 +LH+L LS+ NKL ++ T + LRA+ Sbjct: 389 VDAFQDLHNLNLLSLYDNKLQTIAKGT--FSPLRAI 422 Score = 34.3 bits (77), Expect = 0.26 Identities = 28/102 (27%), Positives = 49/102 (48%), Gaps = 3/102 (2%) Frame = +1 Query: 31 LDVRSNQLKSLPNSIGC-LSKLRVLNVSGNLLQSLPA-TIEECRALEELNANFNQLTRLP 204 L + N L+ P + +KL L++S N +Q++P ++ L ++NQ++ + Sbjct: 108 LRLNRNHLQLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIE 167 Query: 205 DTLGFELHSLRRLSVNSNKLTSLPF-STSHMTALRALDARLN 327 D L L L++N+N +T L S +HM LR N Sbjct: 168 DGAFRALRDLEVLTLNNNNITRLSVASFNHMPKLRTFRLHSN 209 Score = 32.0 bits (71), Expect = 1.3 Identities = 26/108 (24%), Positives = 49/108 (45%), Gaps = 5/108 (4%) Frame = +1 Query: 28 VLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLP-ATIEECRALEELNANFNQLTRLP 204 ++D R L +P ++ + + + N ++ +P + L ++ + NQ++ L Sbjct: 283 IVDCRGKGLTEIPTNLP--ETITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELA 340 Query: 205 DTLGFELHSLRRLSVNSNKLTSLP---FSTSHMTALRALDA-RLNCIR 336 L SL L + NK+T LP F L L+A ++NC+R Sbjct: 341 PDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLR 388 Score = 29.3 bits (64), Expect = 8.3 Identities = 20/65 (30%), Positives = 32/65 (49%) Frame = +1 Query: 79 CLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDTLGFELHSLRRLSVNSN 258 C ++ G L+S+P I R E L+ N N +TR+ T L LR L + N Sbjct: 32 CSCSGSTVDCHGLALRSVPRNIP--RNTERLDLNGNNITRITKTDFAGLRHLRVLQLMEN 89 Query: 259 KLTSL 273 K++++ Sbjct: 90 KISTI 94
>GPV_HUMAN (P40197) Platelet glycoprotein V precursor (GPV) (CD42D antigen)| Length = 560 Score = 36.2 bits (82), Expect = 0.068 Identities = 30/79 (37%), Positives = 44/79 (55%), Gaps = 3/79 (3%) Frame = +1 Query: 49 QLKSLPNS-IGCLSKLRVLNVS-GNLLQSLP-ATIEECRALEELNANFNQLTRLPDTLGF 219 QL++LP + LS+LR L V+ L +LP + L+ L + N LT LPD L Sbjct: 301 QLRTLPAAAFRNLSRLRYLGVTLSPRLSALPQGAFQGLGELQVLALHSNGLTALPDGLLR 360 Query: 220 ELHSLRRLSVNSNKLTSLP 276 L LR++S+ N+L +LP Sbjct: 361 GLGKLRQVSLRRNRLRALP 379
>TLR9_CANFA (Q5I2M8) Toll-like receptor 9 precursor (CD289 antigen)| Length = 1032 Score = 36.2 bits (82), Expect = 0.068 Identities = 36/108 (33%), Positives = 49/108 (45%), Gaps = 9/108 (8%) Frame = +1 Query: 40 RSNQLKSLPNSIGCLSKLRVLNVSGNL---------LQSLPATIEECRALEELNANFNQL 192 R+N L P ++ L LR L + GN LQ P + L L+ +N L Sbjct: 152 RTNILVLDPATLAGLYALRFLFLDGNCYYKNPCQQALQVAPGALLGLGNLTHLSLKYNNL 211 Query: 193 TRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIR 336 T +P L L L LS N + +T P +++TALR LD NC R Sbjct: 212 TVVPRGLPPSLEYLL-LSYN-HIITLAPEDLANLTALRVLDVGGNCRR 257 Score = 35.0 bits (79), Expect = 0.15 Identities = 51/191 (26%), Positives = 79/191 (41%), Gaps = 10/191 (5%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPAT-------IEECRAL 162 +A+L + L + N + S + + LR L+ SGN L + A + R+L Sbjct: 573 VAQLPALRYLSLAHNGIHSRVSQQLRSASLRALDFSGNTLSQMWAEGDLYLRFFQGLRSL 632 Query: 163 EELNANFNQL-TRLPDTLGFELHSLRRLSVNSNKLTSLPFST-SHMTALRALDARLNCIR 336 +L+ + N+L T LP L SLR L + N L +S+ + + L ALD N ++ Sbjct: 633 VQLDLSQNRLHTLLPRNLDNLPKSLRLLRLRDNYLAFFNWSSLALLPKLEALDLAGNQLK 692 Query: 337 AXXXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSIS-VLPDSMGCLAK 513 A LP G T L+ LD+S NSI V+P + Sbjct: 693 ALSNGS--------------------LPNG----TQLQRLDLSGNSIGFVVPSFFALAVR 728 Query: 514 LNKFSAVGNPL 546 L + + N L Sbjct: 729 LRELNLSANAL 739
>R13L3_ARATH (Q9STE7) Putative disease resistance RPP13-like protein 3| Length = 847 Score = 36.2 bits (82), Expect = 0.068 Identities = 28/81 (34%), Positives = 44/81 (54%), Gaps = 1/81 (1%) Frame = +1 Query: 4 IARLLNVV-VLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNAN 180 + R+LN+ +L V N +LP+ IG L LR L ++ + LPA+I R L+ L+A+ Sbjct: 566 LLRVLNMEGLLFVSKNISNTLPDVIGELIHLRYLGIADTYVSILPASISNLRFLQTLDAS 625 Query: 181 FNQLTRLPDTLGFELHSLRRL 243 N + L +L SLR + Sbjct: 626 GNDPFQYTTDLS-KLTSLRHV 645
>SLIT3_MOUSE (Q9WVB4) Slit homolog 3 protein precursor (Slit-3) (Slit3)| Length = 1523 Score = 36.2 bits (82), Expect = 0.068 Identities = 23/87 (26%), Positives = 44/87 (50%), Gaps = 1/87 (1%) Frame = +1 Query: 19 NVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPA-TIEECRALEELNANFNQLT 195 +V L + N L ++P + +L ++++S N + L T L L ++N+L Sbjct: 753 DVTELYLEGNHLTAVPKELSAFRQLTLIDLSNNSISMLTNHTFSNMSHLSTLILSYNRLR 812 Query: 196 RLPDTLGFELHSLRRLSVNSNKLTSLP 276 +P L SLR L+++ N ++S+P Sbjct: 813 CIPVHAFNGLRSLRVLTLHGNDISSVP 839 Score = 30.8 bits (68), Expect = 2.9 Identities = 26/108 (24%), Positives = 53/108 (49%), Gaps = 5/108 (4%) Frame = +1 Query: 28 VLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPA-TIEECRALEELNANFNQLTRLP 204 ++D R L +P ++ + + + N ++S+PA + + L+ ++ + NQ++ + Sbjct: 290 IVDCRGKGLTEIPANLP--EGIVEIRLEQNSIKSIPAGAFTQYKKLKRIDISKNQISDIA 347 Query: 205 DTLGFELHSLRRLSVNSNKLTSLP---FSTSHMTALRALDA-RLNCIR 336 L SL L + NK+T +P F L L+A ++NC+R Sbjct: 348 PDAFQGLKSLTSLVLYGNKITEIPKGLFDGLVSLQLLLLNANKINCLR 395
>LRRN1_RAT (Q32Q07) Leucine-rich repeats neuronal protein 1 precursor| (Neuronal leucine-rich repeat protein 1) (NLRR-1) Length = 716 Score = 35.8 bits (81), Expect = 0.089 Identities = 24/89 (26%), Positives = 45/89 (50%), Gaps = 2/89 (2%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPN-SIGCLSKLRVLNVSGNLLQSLPA-TIEECRALEELNA 177 + +L N+ LD N ++ + L++L L++ N + + +++ L+EL Sbjct: 91 LQQLFNLTELDFSQNNFTNIKEVGLANLTQLTTLHLEENQISEMTDYCLQDLSNLQELYI 150 Query: 178 NFNQLTRLPDTLGFELHSLRRLSVNSNKL 264 N NQ++ + L +L RL +NSNKL Sbjct: 151 NHNQISSISANAFSGLKNLLRLHLNSNKL 179
>LRRN1_MOUSE (Q61809) Leucine-rich repeats neuronal protein 1 precursor| (Neuronal leucine-rich repeat protein 1) (NLRR-1) Length = 716 Score = 35.8 bits (81), Expect = 0.089 Identities = 24/89 (26%), Positives = 45/89 (50%), Gaps = 2/89 (2%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPN-SIGCLSKLRVLNVSGNLLQSLPA-TIEECRALEELNA 177 + +L N+ LD N ++ + L++L L++ N + + +++ L+EL Sbjct: 91 LQQLFNLTELDFSQNNFTNIKEVGLANLTQLTTLHLEENQISEMTDYCLQDLSNLQELYI 150 Query: 178 NFNQLTRLPDTLGFELHSLRRLSVNSNKL 264 N NQ++ + L +L RL +NSNKL Sbjct: 151 NHNQISTISANAFSGLKNLLRLHLNSNKL 179
>DRL33_ARATH (Q9FG90) Probable disease resistance protein At5g43740| Length = 862 Score = 35.8 bits (81), Expect = 0.089 Identities = 22/55 (40%), Positives = 32/55 (58%), Gaps = 1/55 (1%) Frame = +1 Query: 22 VVVLDVRSN-QLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANF 183 +VVLD+ +N L LP I L L+ LN+S ++SLP +++ R L LN F Sbjct: 559 LVVLDLSANLDLIKLPEEISNLGSLQYLNISLTGIKSLPVGLKKLRKLIYLNLEF 613
>LUM_MOUSE (P51885) Lumican precursor (Keratan sulfate proteoglycan lumican)| (KSPG lumican) Length = 338 Score = 35.8 bits (81), Expect = 0.089 Identities = 39/158 (24%), Positives = 75/158 (47%), Gaps = 4/158 (2%) Frame = +1 Query: 31 LDVRSNQLKSLPN-SIGCLSKLRVLNVSGNLLQSLPA---TIEECRALEELNANFNQLTR 198 L +R+NQ+ + + ++ L+ L + NLL++ + + L++L+ N+N LT Sbjct: 71 LYLRNNQIDHIDEKAFENVTDLQWLILDHNLLENSKIKGKVFSKLKQLKKLHINYNNLT- 129 Query: 199 LPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXX 378 +++G SL+ L + +NK++ L S + L + + N ++ Sbjct: 130 --ESVGPLPKSLQDLQLTNNKISKLG-SFDGLVNLTFIYLQHNQLKEDAVSASLKGLKSL 186 Query: 379 XXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPD 492 +F+ + +LP GL TSL L + N IS +PD Sbjct: 187 EYLDLSFNQMSKLPAGLP--TSLLTLYLDNNKISNIPD 222 Score = 31.6 bits (70), Expect = 1.7 Identities = 26/91 (28%), Positives = 45/91 (49%), Gaps = 3/91 (3%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPAT-IEECRALEELNANFNQ 189 L ++ LD+ NQ+ LP G + L L + N + ++P + L+ L + N+ Sbjct: 183 LKSLEYLDLSFNQMSKLP--AGLPTSLLTLYLDNNKISNIPDEYFKRFTGLQYLRLSHNE 240 Query: 190 L--TRLPDTLGFELHSLRRLSVNSNKLTSLP 276 L + +P F + SL L ++ NKL S+P Sbjct: 241 LADSGVPGN-SFNISSLLELDLSYNKLKSIP 270
>LRC27_MOUSE (Q80YS5) Leucine-rich repeat-containing protein 27| Length = 523 Score = 35.8 bits (81), Expect = 0.089 Identities = 19/54 (35%), Positives = 30/54 (55%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELN 174 L N+ LD+R N++K LP+ IG L+ L + N ++ LP + + L LN Sbjct: 99 LPNLTWLDLRYNKIKVLPSGIGSHKHLKTLLLERNPIKMLPVELGQVTTLTALN 152 Score = 33.5 bits (75), Expect = 0.44 Identities = 20/57 (35%), Positives = 29/57 (50%), Gaps = 1/57 (1%) Frame = +1 Query: 400 HFLRELPYGL-GLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPLICPPMDI 567 + LRE+P LL +L LD+ YN I VLP +G L NP+ P+++ Sbjct: 86 NLLREIPEDFFQLLPNLTWLDLRYNKIKVLPSGIGSHKHLKTLLLERNPIKMLPVEL 142 Score = 30.4 bits (67), Expect = 3.7 Identities = 18/59 (30%), Positives = 30/59 (50%) Frame = +1 Query: 397 FHFLRELPYGLGLLTSLRELDISYNSISVLPDSMGCLAKLNKFSAVGNPLICPPMDIVE 573 ++ ++ LP G+G L+ L + N I +LP +G + L + PL PP IV+ Sbjct: 109 YNKIKVLPSGIGSHKHLKTLLLERNPIKMLPVELGQVTTLTALNLRHCPLEFPPRLIVQ 167
>PRELP_BOVIN (Q9GKN8) Prolargin precursor (Proline-arginine-rich end| leucine-rich repeat protein) Length = 381 Score = 35.4 bits (80), Expect = 0.12 Identities = 24/77 (31%), Positives = 39/77 (50%) Frame = +1 Query: 82 LSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDTLGFELHSLRRLSVNSNK 261 L L L + N L+ +PA + R LE+L + NQ++R+P + +L +L L + NK Sbjct: 148 LPSLVFLYLEKNQLEEVPAALP--RNLEQLRLSQNQISRIPPGVFSKLENLLLLDLQHNK 205 Query: 262 LTSLPFSTSHMTALRAL 312 L+ F L+ L Sbjct: 206 LSDGVFKPDTFQGLKNL 222 Score = 32.0 bits (71), Expect = 1.3 Identities = 23/90 (25%), Positives = 45/90 (50%), Gaps = 4/90 (4%) Frame = +1 Query: 19 NVVVLDVRSNQLKSLPNSI-GCLSKLRVLNVSGNLLQS---LPATIEECRALEELNANFN 186 N+ L + NQ+ +P + L L +L++ N L P T + + L +LN N Sbjct: 171 NLEQLRLSQNQISRIPPGVFSKLENLLLLDLQHNKLSDGVFKPDTFQGLKNLMQLNLAHN 230 Query: 187 QLTRLPDTLGFELHSLRRLSVNSNKLTSLP 276 L ++P + +H +L ++SN++ ++P Sbjct: 231 TLRKMPPKVPSAIH---QLYLDSNRIEAIP 257
>SLIK5_HUMAN (O94991) SLIT and NTRK-like protein 5 precursor (Leucine-rich| repeat-containing protein 11) Length = 958 Score = 35.4 bits (80), Expect = 0.12 Identities = 30/105 (28%), Positives = 52/105 (49%), Gaps = 2/105 (1%) Frame = +1 Query: 28 VLDVRSNQLKSLPN-SIGCLSKLRVLNVSGNLLQSL-PATIEECRALEELNANFNQLTRL 201 +L + SN ++ + + L LR L+++ N L+ L T LE L ++N ++ + Sbjct: 109 ILHLGSNVIQDIETGAFHGLRGLRRLHLNNNKLELLRDDTFLGLENLEYLQVDYNYISVI 168 Query: 202 PDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIR 336 +LH L+ L +N N L+SLP + L LD R N ++ Sbjct: 169 EPNAFGKLHLLQVLILNDNLLSSLPNNLFRFVPLTHLDLRGNRLK 213 Score = 33.9 bits (76), Expect = 0.34 Identities = 24/65 (36%), Positives = 34/65 (52%), Gaps = 1/65 (1%) Frame = +1 Query: 13 LLNVVVLDVRSNQLKSL-PNSIGCLSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQ 189 L N+ L V N + + PN+ G L L+VL ++ NLL SLP + L L+ N+ Sbjct: 152 LENLEYLQVDYNYISVIEPNAFGKLHLLQVLILNDNLLSSLPNNLFRFVPLTHLDLRGNR 211 Query: 190 LTRLP 204 L LP Sbjct: 212 LKLLP 216 Score = 30.8 bits (68), Expect = 2.9 Identities = 34/138 (24%), Positives = 59/138 (42%), Gaps = 3/138 (2%) Frame = +1 Query: 148 ECRALEELNANFNQLTRLPDTLGFELHSLRRLSVNSNKLTSL-PFSTSHMTALRALDARL 324 E L+ L+ N+++ + D +L +LRRL +N N++ L P + +L+ L + Sbjct: 431 EATGLDLLHLGNNRISMIQDRAFGDLTNLRRLYLNGNRIERLSPELFYGLQSLQYLFLQY 490 Query: 325 NCIRAXXXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDS--M 498 N IR N + L+ +P G+ +L L++ N + LP S + Sbjct: 491 NLIREIQSGTFDPVPNLQLLFLNN-NLLQAMPSGVFSGLTLLRLNLRSNHFTSLPVSGVL 549 Query: 499 GCLAKLNKFSAVGNPLIC 552 L L + NP C Sbjct: 550 DQLKSLIQIDLHDNPWDC 567
>DRL28_ARATH (O81825) Putative disease resistance protein At4g27220| Length = 919 Score = 35.0 bits (79), Expect = 0.15 Identities = 42/148 (28%), Positives = 69/148 (46%), Gaps = 3/148 (2%) Frame = +1 Query: 31 LDVRSNQLKSLPNSIGCLSKLRVLNVSGNL-LQSLP-ATIEECRALEELNANFNQLTRLP 204 + + +N+L+ LPN++ + VL + GN ++ +P ++ L L+ + ++ LP Sbjct: 475 VSLMANKLERLPNNVIEGVETLVLLLQGNSHVKEVPNGFLQAFPNLRILDLSGVRIRTLP 534 Query: 205 DTLGFELHSLRRLSV-NSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXX 381 D+ LHSLR L + N KL +LP S + L+ LD + IR Sbjct: 535 DSFS-NLHSLRSLVLRNCKKLRNLP-SLESLVKLQFLDLHESAIR--------------- 577 Query: 382 XXSQNFHFLRELPYGLGLLTSLRELDIS 465 ELP GL L+SLR + +S Sbjct: 578 ----------ELPRGLEALSSLRYICVS 595 Score = 33.9 bits (76), Expect = 0.34 Identities = 32/102 (31%), Positives = 57/102 (55%), Gaps = 3/102 (2%) Frame = +1 Query: 19 NVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSG-NLLQSLPATIEECRALEELNANFNQLT 195 N+ +LD+ ++++LP+S L LR L + L++LP ++E L+ L+ + + + Sbjct: 519 NLRILDLSGVRIRTLPDSFSNLHSLRSLVLRNCKKLRNLP-SLESLVKLQFLDLHESAIR 577 Query: 196 RLPDTLGFELHSLRRLSV-NSNKLTSLPFST-SHMTALRALD 315 LP L L SLR + V N+ +L S+P T +++L LD Sbjct: 578 ELPRGLE-ALSSLRYICVSNTYQLQSIPAGTILQLSSLEVLD 618
>TLR9_HUMAN (Q9NR96) Toll-like receptor 9 precursor (CD289 antigen)| Length = 1032 Score = 35.0 bits (79), Expect = 0.15 Identities = 31/99 (31%), Positives = 45/99 (45%), Gaps = 10/99 (10%) Frame = +1 Query: 70 SIGCLSKLRVLNVSGNL---------LQSLPATIEECRALEELNANFNQLTRLPDTLGFE 222 S+ L LR L + GN L+ P + L L+ +N LT +P L Sbjct: 162 SLAGLHALRFLFMDGNCYYKNPCRQALEVAPGALLGLGNLTHLSLKYNNLTVVPRNLP-- 219 Query: 223 LHSLRRLSVNSNKLTSL-PFSTSHMTALRALDARLNCIR 336 SL L ++ N++ L P +++TALR LD NC R Sbjct: 220 -SSLEYLLLSYNRIVKLAPEDLANLTALRVLDVGGNCRR 257 Score = 34.7 bits (78), Expect = 0.20 Identities = 52/191 (27%), Positives = 75/191 (39%), Gaps = 10/191 (5%) Frame = +1 Query: 4 IARLLNVVVLDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQSLPAT-------IEECRAL 162 +A L + L + N + S + C + LR L+ SGN L + A + L Sbjct: 571 VAHLRTLRHLSLAHNNIHSQVSQQLCSTSLRALDFSGNALGHMWAEGDLYLHFFQGLSGL 630 Query: 163 EELNANFNQL-TRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSH-MTALRALDARLNCIR 336 L+ + N+L T LP TL SL+ L + N L + + H + L LD N ++ Sbjct: 631 IWLDLSQNRLHTLLPQTLRNLPKSLQVLRLRDNYLAFFKWWSLHFLPKLEVLDLAGNQLK 690 Query: 337 AXXXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSIS-VLPDSMGCLAK 513 A LP G T LR LD+S NSIS V P + Sbjct: 691 ALTNGS--------------------LPAG----TRLRRLDVSCNSISFVAPGFFSKAKE 726 Query: 514 LNKFSAVGNPL 546 L + + N L Sbjct: 727 LRELNLSANAL 737 Score = 31.2 bits (69), Expect = 2.2 Identities = 46/174 (26%), Positives = 67/174 (38%), Gaps = 14/174 (8%) Frame = +1 Query: 19 NVVVLDVRSNQLKSLPNS-IGCLSKLRVLNVSGNL-------------LQSLPATIEECR 156 NV L + SN++ L +S L LR LN+ N + P+T Sbjct: 64 NVTSLSLSSNRIHHLHDSDFAHLPSLRHLNLKWNCPPVGLSPMHFPCHMTIEPSTFLAVP 123 Query: 157 ALEELNANFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIR 336 LEELN ++N + +P L L SL N L S + H ALR L NC Sbjct: 124 TLEELNLSYNNIMTVP-ALPKSLISLSLSHTNILMLDSASLAGLH--ALRFLFMDGNC-- 178 Query: 337 AXXXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNSISVLPDSM 498 + L P L L +L L + YN+++V+P ++ Sbjct: 179 --------------YYKNPCRQALEVAPGALLGLGNLTHLSLKYNNLTVVPRNL 218
>KERA_HUMAN (O60938) Keratocan precursor (KTN) (Keratan sulfate proteoglycan| keratocan) Length = 352 Score = 35.0 bits (79), Expect = 0.15 Identities = 23/77 (29%), Positives = 38/77 (49%) Frame = +1 Query: 82 LSKLRVLNVSGNLLQSLPATIEECRALEELNANFNQLTRLPDTLGFELHSLRRLSVNSNK 261 L KL L + N L+ +P+ + R+LE+L N+++R+P L +L L + +NK Sbjct: 120 LKKLLFLFLEDNELEEVPSPLP--RSLEQLQLARNKVSRIPQGTFSNLENLTLLDLQNNK 177 Query: 262 LTSLPFSTSHMTALRAL 312 L F L+ L Sbjct: 178 LVDNAFQRDTFKGLKNL 194 Score = 30.0 bits (66), Expect = 4.9 Identities = 23/91 (25%), Positives = 47/91 (51%), Gaps = 3/91 (3%) Frame = +1 Query: 19 NVVVLDVRSNQLKSLP-NSIGCLSKLRVLNVSGNLL--QSLPATIEECRALEELNANFNQ 189 N + L + +N ++ +P N + K+ L ++ N L + LP+ + ++ +L + NQ Sbjct: 214 NTMQLFLDNNSIEGIPENYFNVIPKVAFLRLNHNKLSDEGLPSRGFDVSSILDLQLSHNQ 273 Query: 190 LTRLPDTLGFELHSLRRLSVNSNKLTSLPFS 282 LT++P L+ L ++ NK+ S+ S Sbjct: 274 LTKVPRISA----HLQHLHLDHNKIKSVNVS 300
>LUM_HUMAN (P51884) Lumican precursor (Keratan sulfate proteoglycan lumican)| (KSPG lumican) Length = 338 Score = 35.0 bits (79), Expect = 0.15 Identities = 38/155 (24%), Positives = 68/155 (43%), Gaps = 2/155 (1%) Frame = +1 Query: 31 LDVRSNQLKSLPNSIGCLSKLRVLNVSGNLLQ--SLPATIEECRALEELNANFNQLTRLP 204 L + N++ L + G L L +++ N L+ ++ A + ++LE L+ +FNQ+ RLP Sbjct: 142 LQLTHNKITKLGSFEG-LVNLTFIHLQHNRLKEDAVSAAFKGLKSLEYLDLSFNQIARLP 200 Query: 205 DTLGFELHSLRRLSVNSNKLTSLPFSTSHMTALRALDARLNCIRAXXXXXXXXXXXXXXX 384 L SL L +++NK++++P R N ++ Sbjct: 201 SGLPV---SLLTLYLDNNKISNIP---------DEYFKRFNALQYLRLSHNELADSGIPG 248 Query: 385 XSQNFHFLRELPYGLGLLTSLRELDISYNSISVLP 489 S N ++SL ELD+SYN + +P Sbjct: 249 NSFN-------------VSSLVELDLSYNKLKNIP 270
>FMOD_RABIT (O46378) Fibromodulin (FM) (Collagen-binding 59 kDa protein)| (Keratan sulfate proteoglycan fibromodulin) (KSPG fibromodulin) (Fragment) Length = 147 Score = 35.0 bits (79), Expect = 0.15 Identities = 30/127 (23%), Positives = 58/127 (45%) Frame = +1 Query: 115 NLLQSLPATIEECRALEELNANFNQLTRLPDTLGFELHSLRRLSVNSNKLTSLPFSTSHM 294 N L +P + R+L EL+ + NQ++R+P+ L +L L + N++ + S + Sbjct: 4 NNLTRMPGPLP--RSLRELHLDHNQISRVPNNALEGLENLTALYLQHNEIQEVGSSMRGL 61 Query: 295 TALRALDARLNCIRAXXXXXXXXXXXXXXXXSQNFHFLRELPYGLGLLTSLRELDISYNS 474 +L LD +++ LR +P GL ++L +L + +N+ Sbjct: 62 RSLILLDL-------------------------SYNHLRRVPDGLP--SALEQLYLEHNN 94 Query: 475 ISVLPDS 495 + +PDS Sbjct: 95 VYTVPDS 101 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 63,879,582 Number of Sequences: 219361 Number of extensions: 1175320 Number of successful extensions: 7635 Number of sequences better than 10.0: 358 Number of HSP's better than 10.0 without gapping: 5566 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 7017 length of database: 80,573,946 effective HSP length: 106 effective length of database: 57,321,680 effective search space used: 4815021120 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)