ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
menu 
| Clone Name | bart43f04 |
|---|---|
| Clone Library Name | barley_pub |
>GBLP_ORYSA (P49027) Guanine nucleotide-binding protein beta subunit-like| protein (GPB-LR) (RWD) Length = 334 Score = 298 bits (763), Expect = 7e-81 Identities = 148/162 (91%), Positives = 153/162 (94%), Gaps = 2/162 (1%) Frame = +1 Query: 73 MAGAQESLVYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTS- 249 MAGAQESLV AGVM GHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNP+Q + + Sbjct: 1 MAGAQESLVLAGVMHGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPVQNVGEGAG 60 Query: 250 -SEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDV 426 SEYGVPFRRLTGH HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGH+KDV Sbjct: 61 ASEYGVPFRRLTGHSHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHDKDV 120 Query: 427 LSVAFSIDNRQIVSASRDRTIKLWNTLGECKYTIGGDLGGGE 552 LSVAFS+DNRQIVSASRDRTIKLWNTLGECKYTIGGDLGGGE Sbjct: 121 LSVAFSVDNRQIVSASRDRTIKLWNTLGECKYTIGGDLGGGE 162 Score = 57.4 bits (137), Expect = 3e-08 Identities = 44/131 (33%), Positives = 63/131 (48%), Gaps = 3/131 (2%) Frame = +1 Query: 118 GHNDVVTAIA-TPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGH 294 GHN V+ + +P P IVS S D+++ VW+LTN L GHG Sbjct: 163 GHNGWVSCVRFSPNTFQPTIVSGSWDRTVKVWNLTNCKLRCN------------LEGHGG 210 Query: 295 FVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKD--VLSVAFSIDNRQIVS 468 +V V +S DG SG DG LWDL+ G +R + + S+ FS NR + Sbjct: 211 YVNAVAVSPDGSLCASGGKDGVTLLWDLAEG---KRLYSLDAGSIIHSLCFS-PNRYWLC 266 Query: 469 ASRDRTIKLWN 501 A+ +IK+W+ Sbjct: 267 AATQDSIKIWD 277
>GBLP_MEDSA (O24076) Guanine nucleotide-binding protein beta subunit-like| protein Length = 325 Score = 225 bits (574), Expect = 6e-59 Identities = 113/147 (76%), Positives = 120/147 (81%) Frame = +1 Query: 88 ESLVYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVP 267 E LV G MR H DVVTAIATPIDNS IV++SRDKS+++W LT YGVP Sbjct: 3 EGLVLRGTMRAHTDVVTAIATPIDNSDMIVTASRDKSIILWHLTKE-------DKTYGVP 55 Query: 268 FRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSI 447 RRLTGH HFVQDVVLSSDGQFALSGSWDGELRLWDL+ G + RRFVGH KDVLSVAFSI Sbjct: 56 RRRLTGHSHFVQDVVLSSDGQFALSGSWDGELRLWDLNAGTSARRFVGHTKDVLSVAFSI 115 Query: 448 DNRQIVSASRDRTIKLWNTLGECKYTI 528 DNRQIVSASRDRTIKLWNTLGECKYTI Sbjct: 116 DNRQIVSASRDRTIKLWNTLGECKYTI 142 Score = 58.5 bits (140), Expect = 1e-08 Identities = 40/129 (31%), Positives = 64/129 (49%), Gaps = 2/129 (1%) Frame = +1 Query: 121 HNDVVTAIA-TPIDNSPFIVSSSRDKSLLVWDLTN-PIQATQDTSSEYGVPFRRLTGHGH 294 H+D V+ + +P P IVS+S D+++ VW+LTN ++ T L GH Sbjct: 148 HSDWVSCVRFSPSTPQPTIVSASWDRTVKVWNLTNCKLRNT-------------LAGHSG 194 Query: 295 FVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSAS 474 +V V +S DG SG DG + LWDL+ G R + ++ NR + A+ Sbjct: 195 YVNTVAVSPDGSLCASGGKDGVILLWDLAEG--KRLYSLDAGSIIHALCFSPNRYWLCAA 252 Query: 475 RDRTIKLWN 501 + +IK+W+ Sbjct: 253 TESSIKIWD 261
>GBLP_BRANA (Q39336) Guanine nucleotide-binding protein beta subunit-like| protein Length = 327 Score = 224 bits (572), Expect = 1e-58 Identities = 115/152 (75%), Positives = 124/152 (81%), Gaps = 2/152 (1%) Frame = +1 Query: 88 ESLVYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVP 267 E LV G MR H D+VTAIATPIDNS IVS+SRDKS++VW LT YGV Sbjct: 3 EGLVLKGTMRAHTDMVTAIATPIDNSDTIVSASRDKSIIVWKLTKD-------DKSYGVR 55 Query: 268 FRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSI 447 RRLTGH HFV+DVVLSSDGQFALSGSWDGELRLWDL+ GV+TRRFVGH KDVLSVAFS+ Sbjct: 56 QRRLTGHSHFVEDVVLSSDGQFALSGSWDGELRLWDLAAGVSTRRFVGHTKDVLSVAFSL 115 Query: 448 DNRQIVSASRDRTIKLWNTLGECKYTI--GGD 537 DNRQIVSASRDRTIKLWNTLGECKYTI GG+ Sbjct: 116 DNRQIVSASRDRTIKLWNTLGECKYTISEGGE 147 Score = 59.7 bits (143), Expect = 5e-09 Identities = 41/130 (31%), Positives = 65/130 (50%), Gaps = 2/130 (1%) Frame = +1 Query: 118 GHNDVVTAIA-TPIDNSPFIVSSSRDKSLLVWDLTN-PIQATQDTSSEYGVPFRRLTGHG 291 GH D V+ + +P P IVS+S DK++ VW+L+N +++T L GH Sbjct: 148 GHRDWVSCVRFSPNTLQPTIVSASCDKTVKVWNLSNCKLRST-------------LAGHT 194 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSA 471 +V V +S DG SG DG + LWDL+ G + + V+ NR + A Sbjct: 195 GYVSTVAVSPDGSLCASGGKDGVVLLWDLAEG--KKLYSLEANSVIHALCFTPNRYWLCA 252 Query: 472 SRDRTIKLWN 501 + ++ IK+W+ Sbjct: 253 ATEQGIKIWD 262
>GBLP_ARATH (O24456) Guanine nucleotide-binding protein beta subunit-like| protein (WD-40 repeat auxin-dependent protein ARCA) Length = 327 Score = 224 bits (571), Expect = 1e-58 Identities = 114/152 (75%), Positives = 126/152 (82%), Gaps = 2/152 (1%) Frame = +1 Query: 88 ESLVYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVP 267 E LV G MR H D+VTAIATPIDN+ IVS+SRDKS+++W LT +A YGV Sbjct: 3 EGLVLKGTMRAHTDMVTAIATPIDNADIIVSASRDKSIILWKLTKDDKA-------YGVA 55 Query: 268 FRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSI 447 RRLTGH HFV+DVVLSSDGQFALSGSWDGELRLWDL+ GV+TRRFVGH KDVLSVAFS+ Sbjct: 56 QRRLTGHSHFVEDVVLSSDGQFALSGSWDGELRLWDLAAGVSTRRFVGHTKDVLSVAFSL 115 Query: 448 DNRQIVSASRDRTIKLWNTLGECKYTI--GGD 537 DNRQIVSASRDRTIKLWNTLGECKYTI GG+ Sbjct: 116 DNRQIVSASRDRTIKLWNTLGECKYTISEGGE 147 Score = 58.9 bits (141), Expect = 9e-09 Identities = 41/130 (31%), Positives = 64/130 (49%), Gaps = 2/130 (1%) Frame = +1 Query: 118 GHNDVVTAIA-TPIDNSPFIVSSSRDKSLLVWDLTN-PIQATQDTSSEYGVPFRRLTGHG 291 GH D V+ + +P P IVS+S DK++ VW+L+N +++T L GH Sbjct: 148 GHRDWVSCVRFSPNTLQPTIVSASWDKTVKVWNLSNCKLRST-------------LAGHT 194 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSA 471 +V V +S DG SG DG + LWDL+ G + + V+ NR + A Sbjct: 195 GYVSTVAVSPDGSLCASGGKDGVVLLWDLAEG--KKLYSLEANSVIHALCFSPNRYWLCA 252 Query: 472 SRDRTIKLWN 501 + + IK+W+ Sbjct: 253 ATEHGIKIWD 262
>GBLP_SOYBN (Q39836) Guanine nucleotide-binding protein beta subunit-like| protein Length = 325 Score = 224 bits (571), Expect = 1e-58 Identities = 112/147 (76%), Positives = 120/147 (81%) Frame = +1 Query: 88 ESLVYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVP 267 E LV G MR H DVVTAIATPIDNS IV++SRD+S+++W LT YGVP Sbjct: 3 EGLVLKGTMRAHTDVVTAIATPIDNSDMIVTASRDRSIILWHLTKE-------DKTYGVP 55 Query: 268 FRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSI 447 RRLTGH HFVQDVVLSSDGQFALSGSWDGELRLWDL+ G + RRFVGH KDVLSVAFSI Sbjct: 56 RRRLTGHSHFVQDVVLSSDGQFALSGSWDGELRLWDLAAGTSARRFVGHTKDVLSVAFSI 115 Query: 448 DNRQIVSASRDRTIKLWNTLGECKYTI 528 DNRQIVSASRDRTIKLWNTLGECKYTI Sbjct: 116 DNRQIVSASRDRTIKLWNTLGECKYTI 142 Score = 57.0 bits (136), Expect = 3e-08 Identities = 39/129 (30%), Positives = 65/129 (50%), Gaps = 2/129 (1%) Frame = +1 Query: 121 HNDVVTAIA-TPIDNSPFIVSSSRDKSLLVWDLTN-PIQATQDTSSEYGVPFRRLTGHGH 294 H+D V+ + +P P IVS+S D+++ VW+LTN ++ T L GH Sbjct: 148 HSDWVSCVRFSPSTLQPTIVSASWDRTVKVWNLTNCKLRNT-------------LAGHNG 194 Query: 295 FVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSAS 474 +V V +S DG SG DG + LWDL+ G R + ++ +R + A+ Sbjct: 195 YVNTVAVSPDGSLCASGGKDGVILLWDLAEG--KRLYSLDAGSIIHALCFSPSRYWLCAA 252 Query: 475 RDRTIKLWN 501 +++IK+W+ Sbjct: 253 TEQSIKIWD 261
>GBLP_TOBAC (P49026) Guanine nucleotide-binding protein beta subunit-like| protein Length = 326 Score = 223 bits (568), Expect = 3e-58 Identities = 110/149 (73%), Positives = 121/149 (81%) Frame = +1 Query: 82 AQESLVYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYG 261 +QESLV G MR H D VTAIAT +DNS IV+SSRDKS++VW +T +YG Sbjct: 2 SQESLVLRGTMRAHTDWVTAIATAVDNSDMIVTSSRDKSIIVWSITKD-------GPQYG 54 Query: 262 VPFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAF 441 VP RRLTGHGHFVQDVVLSSDG FALSGSWDGELRLWDL G T RRFVGH KDVLSVAF Sbjct: 55 VPRRRLTGHGHFVQDVVLSSDGMFALSGSWDGELRLWDLQAGTTARRFVGHTKDVLSVAF 114 Query: 442 SIDNRQIVSASRDRTIKLWNTLGECKYTI 528 S+DNRQIVSASRD++I+LWNTLGECKYTI Sbjct: 115 SVDNRQIVSASRDKSIRLWNTLGECKYTI 143 Score = 55.5 bits (132), Expect = 1e-07 Identities = 41/131 (31%), Positives = 67/131 (51%), Gaps = 4/131 (3%) Frame = +1 Query: 121 HNDVVTAIA-TPIDNSPFIVSSSRDKSLLVWDLTN-PIQATQDTSSEYGVPFRRLTGHGH 294 H+D V+ + +P + P IVS S D+++ +W+LTN ++ T L GH Sbjct: 149 HSDWVSCVRFSPNNLQPTIVSGSWDRTVKIWNLTNCKLRLT-------------LAGHTG 195 Query: 295 FVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKD--VLSVAFSIDNRQIVS 468 +V +S DG SG DG + LWDL+ G ++ E + S+ FS NR + Sbjct: 196 YVNTPAVSPDGSLCASGGKDGVILLWDLAEG---KKLYSLESGSIIHSLCFS-PNRYWLC 251 Query: 469 ASRDRTIKLWN 501 A+ + +IK+W+ Sbjct: 252 AATESSIKIWD 262 Score = 53.9 bits (128), Expect = 3e-07 Identities = 41/131 (31%), Positives = 60/131 (45%), Gaps = 3/131 (2%) Frame = +1 Query: 118 GHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQAT-QDTSSEYGVPFRRLTGHGH 294 GH V ++A +DN IVS+SRDKS+ +W+ + T QD S H Sbjct: 104 GHTKDVLSVAFSVDNRQ-IVSASRDKSIRLWNTLGECKYTIQDGDS-----------HSD 151 Query: 295 FVQDVVLSSDG--QFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVS 468 +V V S + +SGSWD +++W+L+ GH V + A S D S Sbjct: 152 WVSCVRFSPNNLQPTIVSGSWDRTVKIWNLTNCKLRLTLAGHTGYVNTPAVSPDGSLCAS 211 Query: 469 ASRDRTIKLWN 501 +D I LW+ Sbjct: 212 GGKDGVILLWD 222
>GBLP_NICPL (P93340) Guanine nucleotide-binding protein beta subunit-like| protein Length = 326 Score = 221 bits (563), Expect = 1e-57 Identities = 110/149 (73%), Positives = 119/149 (79%) Frame = +1 Query: 82 AQESLVYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYG 261 + ESLV G MR H D VTAIATP+DNS IV+SSRDKS++VW LT +YG Sbjct: 2 SHESLVLRGTMRAHTDWVTAIATPVDNSDMIVTSSRDKSIIVWSLTKD-------GPQYG 54 Query: 262 VPFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAF 441 VP RRLTGHGHFVQDVVLSSDG FALSGSWDGELRLWDL G T RRFVGH KDVLSVAF Sbjct: 55 VPRRRLTGHGHFVQDVVLSSDGMFALSGSWDGELRLWDLQAGTTARRFVGHTKDVLSVAF 114 Query: 442 SIDNRQIVSASRDRTIKLWNTLGECKYTI 528 S DNRQIVSASRD++I+LWNTLGECKY I Sbjct: 115 SADNRQIVSASRDKSIRLWNTLGECKYII 143 Score = 58.2 bits (139), Expect = 2e-08 Identities = 42/131 (32%), Positives = 68/131 (51%), Gaps = 4/131 (3%) Frame = +1 Query: 121 HNDVVTAIA-TPIDNSPFIVSSSRDKSLLVWDLTN-PIQATQDTSSEYGVPFRRLTGHGH 294 H+D V+ + +P + P IVS S D+++ +W+LTN ++AT L GH Sbjct: 149 HSDWVSCVRFSPNNLQPTIVSGSWDRTVKIWNLTNCKLRAT-------------LAGHTG 195 Query: 295 FVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKD--VLSVAFSIDNRQIVS 468 +V +S DG SG DG + LWDL+ G ++ E + S+ FS NR + Sbjct: 196 YVNTTAVSPDGSLCASGGKDGVILLWDLAEG---KKLYSLESGSIIHSLCFS-PNRYWLC 251 Query: 469 ASRDRTIKLWN 501 A+ + +IK+W+ Sbjct: 252 AATESSIKIWD 262 Score = 51.6 bits (122), Expect = 1e-06 Identities = 40/131 (30%), Positives = 58/131 (44%), Gaps = 3/131 (2%) Frame = +1 Query: 118 GHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQ-ATQDTSSEYGVPFRRLTGHGH 294 GH V ++A DN IVS+SRDKS+ +W+ + QD S H Sbjct: 104 GHTKDVLSVAFSADNRQ-IVSASRDKSIRLWNTLGECKYIIQDGDS-----------HSD 151 Query: 295 FVQDVVLSSDG--QFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVS 468 +V V S + +SGSWD +++W+L+ GH V + A S D S Sbjct: 152 WVSCVRFSPNNLQPTIVSGSWDRTVKIWNLTNCKLRATLAGHTGYVNTTAVSPDGSLCAS 211 Query: 469 ASRDRTIKLWN 501 +D I LW+ Sbjct: 212 GGKDGVILLWD 222
>GBLP_CHLRE (P25387) Guanine nucleotide-binding protein beta subunit-like| protein Length = 318 Score = 200 bits (508), Expect = 3e-51 Identities = 101/156 (64%), Positives = 120/156 (76%), Gaps = 1/156 (0%) Frame = +1 Query: 88 ESLVYAGVMRGHNDVVTAIATPID-NSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGV 264 E+L ++GH + VTAIATP+D +S ++S+SRDKS+LVW+L + + S YG Sbjct: 3 ETLTLRATLKGHTNWVTAIATPLDPSSNTLLSASRDKSVLVWEL-------ERSESNYGY 55 Query: 265 PFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFS 444 + L GH HFVQDVV+SSDGQF L+GSWDG LRLWDL+TG TTRRFVGH KDVLSVAFS Sbjct: 56 ARKALRGHSHFVQDVVISSDGQFCLTGSWDGTLRLWDLNTGTTTRRFVGHTKDVLSVAFS 115 Query: 445 IDNRQIVSASRDRTIKLWNTLGECKYTIGGDLGGGE 552 +DNRQIVS SRD+TIKLWNTLGECKYTIG G E Sbjct: 116 VDNRQIVSGSRDKTIKLWNTLGECKYTIGEPEGHTE 151 Score = 60.5 bits (145), Expect = 3e-09 Identities = 42/133 (31%), Positives = 60/133 (45%), Gaps = 1/133 (0%) Frame = +1 Query: 106 GVMRGHNDVVTAIA-TPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLT 282 G GH + V+ + +P+ +P IVS DK + VW+LTN L Sbjct: 144 GEPEGHTEWVSCVRFSPMTTNPIIVSGGWDKMVKVWNLTNCKLKNN------------LV 191 Query: 283 GHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQI 462 GH +V V +S DG SG DG LWDL+ G R + DV+ NR Sbjct: 192 GHHGYVNTVTVSPDGSLCASGGKDGIAMLWDLAEG--KRLYSLDAGDVIHCLCFSPNRYW 249 Query: 463 VSASRDRTIKLWN 501 + A+ +IK+W+ Sbjct: 250 LCAATQSSIKIWD 262
>GBLP_BIOGL (Q93134) Guanine nucleotide-binding protein beta subunit 2-like 1| (Receptor of activated protein kinase C) (RACK) Length = 316 Score = 194 bits (492), Expect = 2e-49 Identities = 100/150 (66%), Positives = 109/150 (72%) Frame = +1 Query: 88 ESLVYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVP 267 E + G ++GH VT IAT I+S+SRDKSL+VW LT S YGVP Sbjct: 3 EQMTLRGTLQGHGGWVTQIATTPQYPDMILSASRDKSLIVWRLTRD-------ESSYGVP 55 Query: 268 FRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSI 447 + L GHGHFV DV+LSSDGQFALSGSWD LRLWDLSTG TTRRFVGH KDVLSVAFS Sbjct: 56 QKSLHGHGHFVSDVILSSDGQFALSGSWDHTLRLWDLSTGQTTRRFVGHTKDVLSVAFSA 115 Query: 448 DNRQIVSASRDRTIKLWNTLGECKYTIGGD 537 DNRQIVS SRD+TIKLWNTLG CKYTI D Sbjct: 116 DNRQIVSGSRDKTIKLWNTLGVCKYTIQDD 145 Score = 55.1 bits (131), Expect = 1e-07 Identities = 39/132 (29%), Positives = 59/132 (44%), Gaps = 1/132 (0%) Frame = +1 Query: 121 HNDVVTAIA-TPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHF 297 H D + + +P +P IVSS D+ + VW+LTN T GH + Sbjct: 147 HTDWTSCVRFSPNTQNPIIVSSGWDRLVKVWNLTNCKLKTNHY------------GHTGY 194 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASR 477 V V +S DG SG D + LWDL+ G G + ++ FS NR + + Sbjct: 195 VNTVTVSPDGSLCASGGKDSQAMLWDLNEGKHLYTLDGAGDTINALCFS-PNRYWLCVAS 253 Query: 478 DRTIKLWNTLGE 513 +IK+W+ G+ Sbjct: 254 GPSIKIWDLEGK 265
>GBLP_RAT (P63245) Guanine nucleotide-binding protein beta subunit 2-like 1| (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase) Length = 316 Score = 191 bits (486), Expect = 9e-49 Identities = 94/147 (63%), Positives = 109/147 (74%) Frame = +1 Query: 88 ESLVYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVP 267 E + G ++GHN VT IAT I+S+SRDK++++W LT + YG+P Sbjct: 2 EQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRD-------ETNYGIP 54 Query: 268 FRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSI 447 R L GH HFV DVV+SSDGQFALSGSWDG LRLWDL+TG TTRRFVGH KDVLSVAFS Sbjct: 55 QRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSS 114 Query: 448 DNRQIVSASRDRTIKLWNTLGECKYTI 528 DNRQIVS SRD+TIKLWNTLG CKYT+ Sbjct: 115 DNRQIVSGSRDKTIKLWNTLGVCKYTV 141 Score = 55.1 bits (131), Expect = 1e-07 Identities = 38/132 (28%), Positives = 61/132 (46%), Gaps = 1/132 (0%) Frame = +1 Query: 121 HNDVVTAIA-TPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHF 297 H++ V+ + +P ++P IVS DK + VW+L N T GH + Sbjct: 146 HSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHI------------GHTGY 193 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASR 477 + V +S DG SG DG+ LWDL+ G G D+++ NR + A+ Sbjct: 194 LNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG--GDIINALCFSPNRYWLCAAT 251 Query: 478 DRTIKLWNTLGE 513 +IK+W+ G+ Sbjct: 252 GPSIKIWDLEGK 263
>GBLP_PIG (P63246) Guanine nucleotide-binding protein beta subunit 2-like 1| (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase) Length = 316 Score = 191 bits (486), Expect = 9e-49 Identities = 94/147 (63%), Positives = 109/147 (74%) Frame = +1 Query: 88 ESLVYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVP 267 E + G ++GHN VT IAT I+S+SRDK++++W LT + YG+P Sbjct: 2 EQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRD-------ETNYGIP 54 Query: 268 FRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSI 447 R L GH HFV DVV+SSDGQFALSGSWDG LRLWDL+TG TTRRFVGH KDVLSVAFS Sbjct: 55 QRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSS 114 Query: 448 DNRQIVSASRDRTIKLWNTLGECKYTI 528 DNRQIVS SRD+TIKLWNTLG CKYT+ Sbjct: 115 DNRQIVSGSRDKTIKLWNTLGVCKYTV 141 Score = 55.1 bits (131), Expect = 1e-07 Identities = 38/132 (28%), Positives = 61/132 (46%), Gaps = 1/132 (0%) Frame = +1 Query: 121 HNDVVTAIA-TPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHF 297 H++ V+ + +P ++P IVS DK + VW+L N T GH + Sbjct: 146 HSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHI------------GHTGY 193 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASR 477 + V +S DG SG DG+ LWDL+ G G D+++ NR + A+ Sbjct: 194 LNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG--GDIINALCFSPNRYWLCAAT 251 Query: 478 DRTIKLWNTLGE 513 +IK+W+ G+ Sbjct: 252 GPSIKIWDLEGK 263
>GBLP_MOUSE (P68040) Guanine nucleotide-binding protein beta subunit 2-like 1| (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase) (p205) (12-3) Length = 316 Score = 191 bits (486), Expect = 9e-49 Identities = 94/147 (63%), Positives = 109/147 (74%) Frame = +1 Query: 88 ESLVYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVP 267 E + G ++GHN VT IAT I+S+SRDK++++W LT + YG+P Sbjct: 2 EQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRD-------ETNYGIP 54 Query: 268 FRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSI 447 R L GH HFV DVV+SSDGQFALSGSWDG LRLWDL+TG TTRRFVGH KDVLSVAFS Sbjct: 55 QRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSS 114 Query: 448 DNRQIVSASRDRTIKLWNTLGECKYTI 528 DNRQIVS SRD+TIKLWNTLG CKYT+ Sbjct: 115 DNRQIVSGSRDKTIKLWNTLGVCKYTV 141 Score = 55.1 bits (131), Expect = 1e-07 Identities = 38/132 (28%), Positives = 61/132 (46%), Gaps = 1/132 (0%) Frame = +1 Query: 121 HNDVVTAIA-TPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHF 297 H++ V+ + +P ++P IVS DK + VW+L N T GH + Sbjct: 146 HSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHI------------GHTGY 193 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASR 477 + V +S DG SG DG+ LWDL+ G G D+++ NR + A+ Sbjct: 194 LNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG--GDIINALCFSPNRYWLCAAT 251 Query: 478 DRTIKLWNTLGE 513 +IK+W+ G+ Sbjct: 252 GPSIKIWDLEGK 263
>GBLP_MACFA (Q4R7Y4) Guanine nucleotide-binding protein beta subunit 2-like 1| Length = 316 Score = 191 bits (486), Expect = 9e-49 Identities = 94/147 (63%), Positives = 109/147 (74%) Frame = +1 Query: 88 ESLVYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVP 267 E + G ++GHN VT IAT I+S+SRDK++++W LT + YG+P Sbjct: 2 EQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRD-------ETNYGIP 54 Query: 268 FRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSI 447 R L GH HFV DVV+SSDGQFALSGSWDG LRLWDL+TG TTRRFVGH KDVLSVAFS Sbjct: 55 QRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSS 114 Query: 448 DNRQIVSASRDRTIKLWNTLGECKYTI 528 DNRQIVS SRD+TIKLWNTLG CKYT+ Sbjct: 115 DNRQIVSGSRDKTIKLWNTLGVCKYTV 141 Score = 55.1 bits (131), Expect = 1e-07 Identities = 38/132 (28%), Positives = 61/132 (46%), Gaps = 1/132 (0%) Frame = +1 Query: 121 HNDVVTAIA-TPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHF 297 H++ V+ + +P ++P IVS DK + VW+L N T GH + Sbjct: 146 HSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHI------------GHTGY 193 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASR 477 + V +S DG SG DG+ LWDL+ G G D+++ NR + A+ Sbjct: 194 LNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG--GDIINALCFSPNRYWLCAAT 251 Query: 478 DRTIKLWNTLGE 513 +IK+W+ G+ Sbjct: 252 GPSIKIWDLEGK 263
>GBLP_HUMAN (P63244) Guanine nucleotide-binding protein beta subunit 2-like 1| (Guanine nucleotide-binding protein beta subunit-like protein 12.3) (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase) Length = 316 Score = 191 bits (486), Expect = 9e-49 Identities = 94/147 (63%), Positives = 109/147 (74%) Frame = +1 Query: 88 ESLVYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVP 267 E + G ++GHN VT IAT I+S+SRDK++++W LT + YG+P Sbjct: 2 EQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRD-------ETNYGIP 54 Query: 268 FRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSI 447 R L GH HFV DVV+SSDGQFALSGSWDG LRLWDL+TG TTRRFVGH KDVLSVAFS Sbjct: 55 QRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSS 114 Query: 448 DNRQIVSASRDRTIKLWNTLGECKYTI 528 DNRQIVS SRD+TIKLWNTLG CKYT+ Sbjct: 115 DNRQIVSGSRDKTIKLWNTLGVCKYTV 141 Score = 55.1 bits (131), Expect = 1e-07 Identities = 38/132 (28%), Positives = 61/132 (46%), Gaps = 1/132 (0%) Frame = +1 Query: 121 HNDVVTAIA-TPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHF 297 H++ V+ + +P ++P IVS DK + VW+L N T GH + Sbjct: 146 HSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHI------------GHTGY 193 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASR 477 + V +S DG SG DG+ LWDL+ G G D+++ NR + A+ Sbjct: 194 LNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG--GDIINALCFSPNRYWLCAAT 251 Query: 478 DRTIKLWNTLGE 513 +IK+W+ G+ Sbjct: 252 GPSIKIWDLEGK 263
>GBLP_BOVIN (P63243) Guanine nucleotide-binding protein beta subunit 2-like 1| (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase) Length = 316 Score = 191 bits (486), Expect = 9e-49 Identities = 94/147 (63%), Positives = 109/147 (74%) Frame = +1 Query: 88 ESLVYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVP 267 E + G ++GHN VT IAT I+S+SRDK++++W LT + YG+P Sbjct: 2 EQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRD-------ETNYGIP 54 Query: 268 FRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSI 447 R L GH HFV DVV+SSDGQFALSGSWDG LRLWDL+TG TTRRFVGH KDVLSVAFS Sbjct: 55 QRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSS 114 Query: 448 DNRQIVSASRDRTIKLWNTLGECKYTI 528 DNRQIVS SRD+TIKLWNTLG CKYT+ Sbjct: 115 DNRQIVSGSRDKTIKLWNTLGVCKYTV 141 Score = 55.1 bits (131), Expect = 1e-07 Identities = 38/132 (28%), Positives = 61/132 (46%), Gaps = 1/132 (0%) Frame = +1 Query: 121 HNDVVTAIA-TPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHF 297 H++ V+ + +P ++P IVS DK + VW+L N T GH + Sbjct: 146 HSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHI------------GHTGY 193 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASR 477 + V +S DG SG DG+ LWDL+ G G D+++ NR + A+ Sbjct: 194 LNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG--GDIINALCFSPNRYWLCAAT 251 Query: 478 DRTIKLWNTLGE 513 +IK+W+ G+ Sbjct: 252 GPSIKIWDLEGK 263
>GBLP_CHICK (P63247) Guanine nucleotide-binding protein beta subunit 2-like 1| (Guanine nucleotide-binding protein beta subunit-like protein 12.3) (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase) Length = 317 Score = 191 bits (486), Expect = 9e-49 Identities = 94/147 (63%), Positives = 109/147 (74%) Frame = +1 Query: 88 ESLVYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVP 267 E + G ++GHN VT IAT I+S+SRDK++++W LT + YG+P Sbjct: 3 EQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRD-------ETNYGIP 55 Query: 268 FRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSI 447 R L GH HFV DVV+SSDGQFALSGSWDG LRLWDL+TG TTRRFVGH KDVLSVAFS Sbjct: 56 QRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSS 115 Query: 448 DNRQIVSASRDRTIKLWNTLGECKYTI 528 DNRQIVS SRD+TIKLWNTLG CKYT+ Sbjct: 116 DNRQIVSGSRDKTIKLWNTLGVCKYTV 142 Score = 55.1 bits (131), Expect = 1e-07 Identities = 38/132 (28%), Positives = 61/132 (46%), Gaps = 1/132 (0%) Frame = +1 Query: 121 HNDVVTAIA-TPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHF 297 H++ V+ + +P ++P IVS DK + VW+L N T GH + Sbjct: 147 HSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHI------------GHTGY 194 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASR 477 + V +S DG SG DG+ LWDL+ G G D+++ NR + A+ Sbjct: 195 LNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG--GDIINALCFSPNRYWLCAAT 252 Query: 478 DRTIKLWNTLGE 513 +IK+W+ G+ Sbjct: 253 GPSIKIWDLEGK 264
>GBLP_BRARE (O42248) Guanine nucleotide-binding protein beta subunit 2-like 1| (Receptor of activated protein kinase C) (RACK) Length = 317 Score = 191 bits (486), Expect = 9e-49 Identities = 95/150 (63%), Positives = 110/150 (73%) Frame = +1 Query: 88 ESLVYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVP 267 E + G ++GH+ VT IAT I+S+SRDK++++W LT + YG+P Sbjct: 3 EQMTVRGTLKGHSGWVTQIATTPQFPDMILSASRDKTIIMWKLTRD-------ETNYGIP 55 Query: 268 FRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSI 447 R L GH HFV DVV+SSDGQFALSGSWDG LRLWDL+TG TTRRFVGH KDVLSVAFS Sbjct: 56 QRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSA 115 Query: 448 DNRQIVSASRDRTIKLWNTLGECKYTIGGD 537 DNRQIVS SRD+TIKLWNTLG CKYTI D Sbjct: 116 DNRQIVSGSRDKTIKLWNTLGVCKYTIQDD 145 Score = 53.9 bits (128), Expect = 3e-07 Identities = 38/132 (28%), Positives = 59/132 (44%), Gaps = 1/132 (0%) Frame = +1 Query: 121 HNDVVTAIA-TPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHF 297 H + V+ + +P ++P IVS DK + VW+L N T GH + Sbjct: 147 HTEWVSCVRFSPNSSNPIIVSCGWDKMVKVWNLANCKLKTNHI------------GHTGY 194 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASR 477 + V +S DG SG DG+ LWDL+ G G D ++ NR + A+ Sbjct: 195 LNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG--GDTINALCFSPNRYWLCAAT 252 Query: 478 DRTIKLWNTLGE 513 +IK+W+ G+ Sbjct: 253 GPSIKIWDLEGK 264
>GBLP_ORENI (O42249) Guanine nucleotide-binding protein beta subunit 2-like 1| (Receptor of activated protein kinase C) (RACK) Length = 317 Score = 191 bits (484), Expect = 2e-48 Identities = 94/147 (63%), Positives = 110/147 (74%) Frame = +1 Query: 88 ESLVYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVP 267 E + G ++GH+ VT IAT I+S+SRDKS+++W LT + YG+P Sbjct: 3 EQMTVRGTLKGHSGWVTQIATTPKYPDMILSASRDKSIIMWKLTRD-------ETNYGIP 55 Query: 268 FRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSI 447 R L GH HFV DVV+SSDGQFALSG+WDG LRLWDL+TG+TTRRFVGH KDVLSVAFS Sbjct: 56 QRSLKGHSHFVSDVVISSDGQFALSGAWDGTLRLWDLTTGLTTRRFVGHTKDVLSVAFSA 115 Query: 448 DNRQIVSASRDRTIKLWNTLGECKYTI 528 DNRQIVS SRD+TIKLWNTLG CKYTI Sbjct: 116 DNRQIVSGSRDKTIKLWNTLGVCKYTI 142 Score = 57.8 bits (138), Expect = 2e-08 Identities = 39/133 (29%), Positives = 61/133 (45%), Gaps = 1/133 (0%) Frame = +1 Query: 118 GHNDVVTAIA-TPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGH 294 GH + V+ + +P ++P IVS DK + VW+L N T GH Sbjct: 146 GHTEWVSCVRFSPNSSNPIIVSCGWDKMVKVWNLANCKLKTNHI------------GHTG 193 Query: 295 FVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSAS 474 ++ V +S DG SG DG+ LWDL+ G + DV++ NR + A+ Sbjct: 194 YLNTVTVSPDGSLCASGGKDGQAMLWDLNEG--KHLYTLDSGDVINALCFSPNRYWLCAA 251 Query: 475 RDRTIKLWNTLGE 513 +IK+W+ G+ Sbjct: 252 TGPSIKIWDLEGK 264
>GBLP_HYDAT (Q25189) Guanine nucleotide-binding protein beta subunit-like| protein (Receptor of activated protein kinase C) (RACK) Length = 317 Score = 189 bits (479), Expect = 6e-48 Identities = 94/147 (63%), Positives = 109/147 (74%) Frame = +1 Query: 88 ESLVYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVP 267 E + G ++GHN VT IAT N I+S+SRDK+L+ W LT +D + YG P Sbjct: 2 EQMTLRGTLKGHNGWVTQIATTPQNPDLILSASRDKTLIQWQLT------RDDQTNYGFP 55 Query: 268 FRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSI 447 + LTGH HFV DVVLSSDGQFALS SWD LRLWDL+ G+TT++FVGH KDVLSVAFS Sbjct: 56 KKCLTGHNHFVSDVVLSSDGQFALSCSWDKTLRLWDLNQGITTKQFVGHTKDVLSVAFSA 115 Query: 448 DNRQIVSASRDRTIKLWNTLGECKYTI 528 DNRQIVS SRD TIKLWNTLG+CKYTI Sbjct: 116 DNRQIVSGSRDNTIKLWNTLGQCKYTI 142 Score = 51.6 bits (122), Expect = 1e-06 Identities = 38/128 (29%), Positives = 57/128 (44%), Gaps = 1/128 (0%) Frame = +1 Query: 121 HNDVVTAIA-TPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHF 297 H++ V+ + +P +P IVS DK + VW+LTN T GH + Sbjct: 147 HSEWVSCVRFSPNTQNPIIVSCGWDKMVKVWNLTNCKLKTNHF------------GHTGY 194 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASR 477 + V +S DG SG DG LWDL+ G G +V++ NR + A+ Sbjct: 195 LNAVTVSPDGSLCASGGKDGNAMLWDLNEGKHLYTLDG--GNVINALCFSPNRYWLCAAT 252 Query: 478 DRTIKLWN 501 IK+W+ Sbjct: 253 GPMIKIWD 260
>GBLP_NEUCR (Q01369) Guanine nucleotide-binding protein beta subunit-like| protein (Cross-pathway control WD-repeat protein cpc-2) Length = 316 Score = 186 bits (473), Expect = 3e-47 Identities = 90/147 (61%), Positives = 108/147 (73%) Frame = +1 Query: 88 ESLVYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVP 267 E L+ G + GHN VT++AT ++N ++S SRDKSL++W+LT + YG P Sbjct: 3 EQLILKGTLEGHNGWVTSLATSLENPNMLLSGSRDKSLIIWNLTRD-------ETSYGYP 55 Query: 268 FRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSI 447 RRL GH H V D V+SSDG +ALS SWD LRLW+LSTG TTRRFVGH DVLSV+FS Sbjct: 56 KRRLHGHSHIVSDCVISSDGAYALSASWDKTLRLWELSTGTTTRRFVGHTNDVLSVSFSA 115 Query: 448 DNRQIVSASRDRTIKLWNTLGECKYTI 528 DNRQIVS SRDRTIKLWNTLG+CK+TI Sbjct: 116 DNRQIVSGSRDRTIKLWNTLGDCKFTI 142 Score = 51.2 bits (121), Expect = 2e-06 Identities = 40/137 (29%), Positives = 65/137 (47%), Gaps = 2/137 (1%) Frame = +1 Query: 118 GHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHF 297 GH + V +++ DN IVS SRD+++ +W N + + T +E GH + Sbjct: 103 GHTNDVLSVSFSADNRQ-IVSGSRDRTIKLW---NTLGDCKFTITE--------KGHTEW 150 Query: 298 VQDVVLSSDGQ--FALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSA 471 V V S + Q +S WD +++W+LS+ +GH + +V S D S Sbjct: 151 VSCVRFSPNPQNPVIVSSGWDKLVKVWELSSCKLQTDHIGHTGYINAVTISPDGSLCASG 210 Query: 472 SRDRTIKLWNTLGECKY 522 +D T LW+ L E K+ Sbjct: 211 GKDGTTMLWD-LNESKH 226
>GBLP_DROME (O18640) Guanine nucleotide-binding protein beta subunit-like| protein (Receptor of activated protein kinase C homolog) Length = 318 Score = 184 bits (468), Expect = 1e-46 Identities = 94/150 (62%), Positives = 109/150 (72%) Frame = +1 Query: 88 ESLVYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVP 267 E+L G + GHN VT IAT + I+S+SRDK+L+VW LT +D + YG P Sbjct: 3 ETLQLRGTLIGHNGWVTQIATNPKDPDTIISASRDKTLIVWKLT------RDEDTNYGYP 56 Query: 268 FRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSI 447 +RL GH HF+ DVVLSSDG +ALSGSWD LRLWDL+ G TTRRF GH KDVLSVAFS Sbjct: 57 QKRLYGHSHFISDVVLSSDGNYALSGSWDQTLRLWDLAAGKTTRRFEGHTKDVLSVAFSA 116 Query: 448 DNRQIVSASRDRTIKLWNTLGECKYTIGGD 537 DNRQIVS SRD+TIKLWNTL ECK+TI D Sbjct: 117 DNRQIVSGSRDKTIKLWNTLAECKFTIQED 146 Score = 53.5 bits (127), Expect = 4e-07 Identities = 37/138 (26%), Positives = 61/138 (44%), Gaps = 1/138 (0%) Frame = +1 Query: 118 GHNDVVTAIA-TPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGH 294 GH D V+ + +P ++P IVS D+++ VW+L N GH Sbjct: 147 GHTDWVSCVRFSPNHSNPIIVSCGWDRTVKVWNLANCKLKNNHH------------GHNG 194 Query: 295 FVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSAS 474 ++ V +S DG SG D + LWDL+ G + D+++ NR + + Sbjct: 195 YLNTVTVSPDGSLCTSGGKDSKALLWDLNDG--KNLYTLEHNDIINALCFSPNRYWLCVA 252 Query: 475 RDRTIKLWNTLGECKYTI 528 +IK+W+ CK T+ Sbjct: 253 YGPSIKIWDL--ACKKTV 268
>GBLP_CAEEL (Q21215) Guanine nucleotide-binding protein beta subunit 2-like 1| Length = 324 Score = 177 bits (450), Expect = 1e-44 Identities = 91/152 (59%), Positives = 108/152 (71%), Gaps = 1/152 (0%) Frame = +1 Query: 85 QESLVYAGVMRGHNDVVTAIATPIDNSPF-IVSSSRDKSLLVWDLTNPIQATQDTSSEYG 261 QE + G + GH VT IAT N ++SSSRDK++LVWD+ + + G Sbjct: 2 QEQMKLTGTLEGHTGWVTQIATYTRNDKTTVLSSSRDKTILVWDVDSVAPVDE---GPIG 58 Query: 262 VPFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAF 441 P R LTGH HFV DVV+SSDGQFALSGSWD LRLWDL+ GV+TR+F+ H KDVLSVAF Sbjct: 59 RPVRSLTGHNHFVSDVVISSDGQFALSGSWDKTLRLWDLNQGVSTRQFISHTKDVLSVAF 118 Query: 442 SIDNRQIVSASRDRTIKLWNTLGECKYTIGGD 537 S DNRQIVS SRD++IKLWNTL +CKYTI D Sbjct: 119 SADNRQIVSGSRDKSIKLWNTLAQCKYTITDD 150 Score = 57.4 bits (137), Expect = 3e-08 Identities = 40/128 (31%), Positives = 59/128 (46%), Gaps = 1/128 (0%) Frame = +1 Query: 121 HNDVVTAIA-TPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHF 297 H D V+ + +P + P IVS+ DK + VW+L N T GH + Sbjct: 152 HTDWVSTVRFSPSNRDPVIVSAGWDKVVKVWNLGNCRLKTNHI------------GHTGY 199 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASR 477 V V +S DG SG DG+ LWDL+ G G+ DV++ NR + A+ Sbjct: 200 VNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLPGN--DVINAMSFSPNRYWLCAAV 257 Query: 478 DRTIKLWN 501 +IK+W+ Sbjct: 258 GSSIKIWD 265
>GBLP_DICDI (P46800) Guanine nucleotide-binding protein beta subunit-like| protein Length = 329 Score = 175 bits (444), Expect = 7e-44 Identities = 89/150 (59%), Positives = 108/150 (72%) Frame = +1 Query: 85 QESLVYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGV 264 Q + + G + GHN VT+IA +N I+SSSRDK+++VW LT P AT G Sbjct: 8 QVTYLEVGSLVGHNGFVTSIAVSPENPDTIISSSRDKTVMVWQLT-PTDATSP-----GK 61 Query: 265 PFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFS 444 R L GH HFVQDVV+S DGQFALSGSWD LRLWD++ GV+TR F GH +DV+SVAFS Sbjct: 62 AHRSLKGHSHFVQDVVISHDGQFALSGSWDNTLRLWDITKGVSTRLFKGHTQDVMSVAFS 121 Query: 445 IDNRQIVSASRDRTIKLWNTLGECKYTIGG 534 DNRQI+S SRD TIK+WNTLGECK+T+ G Sbjct: 122 SDNRQIISGSRDATIKVWNTLGECKFTLEG 151 Score = 51.6 bits (122), Expect = 1e-06 Identities = 33/130 (25%), Positives = 55/130 (42%) Frame = +1 Query: 109 VMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 + +GH V ++A DN I+S SRD ++ VW+ + T + H Sbjct: 107 LFKGHTQDVMSVAFSSDNRQ-IISGSRDATIKVWNTLGECKFTLEGPE----------AH 155 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVS 468 +V + S + +SGSWD ++++WD+ + H V +V S D S Sbjct: 156 QDWVSCIRFSPNTPTIVSGSWDNKVKIWDIKSFKCNHTLTDHTGYVNTVTISPDGSLCAS 215 Query: 469 ASRDRTIKLW 498 +D LW Sbjct: 216 GGKDTFACLW 225 Score = 48.5 bits (114), Expect = 1e-05 Identities = 40/132 (30%), Positives = 60/132 (45%), Gaps = 3/132 (2%) Frame = +1 Query: 121 HNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFR---RLTGHG 291 H D V+ I N+P IVS S D + +WD+ + F+ LT H Sbjct: 155 HQDWVSCIRFS-PNTPTIVSGSWDNKVKIWDIKS---------------FKCNHTLTDHT 198 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSA 471 +V V +S DG SG D LW+LS+G + + ++AFS N+ +SA Sbjct: 199 GYVNTVTISPDGSLCASGGKDTFACLWELSSGKPLYKLEA-RNTINALAFS-PNKYWLSA 256 Query: 472 SRDRTIKLWNTL 507 + D I +W+ L Sbjct: 257 ATDDKIIIWDLL 268
>GBLP_SCHPO (Q10281) Guanine nucleotide-binding protein beta subunit-like| protein (Receptor of activated protein kinase C) Length = 314 Score = 157 bits (396), Expect = 2e-38 Identities = 76/147 (51%), Positives = 96/147 (65%) Frame = +1 Query: 88 ESLVYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVP 267 E LV + GH+ VT+++T +N ++S SRDKS+++W+L YGV Sbjct: 3 EQLVLRATLEGHSGWVTSLSTAPENPDILLSGSRDKSIILWNLVRD-------DVNYGVA 55 Query: 268 FRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSI 447 RRLTGH HFV D LS D +ALS SWD +RLWDL G T +FVGH DVLSV+ S Sbjct: 56 QRRLTGHSHFVSDCALSFDSHYALSASWDKTIRLWDLEKGECTHQFVGHTSDVLSVSISP 115 Query: 448 DNRQIVSASRDRTIKLWNTLGECKYTI 528 DNRQ+VS SRD+TIK+WN +G CKYTI Sbjct: 116 DNRQVVSGSRDKTIKIWNIIGNCKYTI 142 Score = 55.1 bits (131), Expect = 1e-07 Identities = 38/130 (29%), Positives = 56/130 (43%), Gaps = 2/130 (1%) Frame = +1 Query: 118 GHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHF 297 GH V +++ DN +VS SRDK++ +W++ + T GH + Sbjct: 103 GHTSDVLSVSISPDNRQ-VVSGSRDKTIKIWNIIGNCKYTITDG-----------GHSDW 150 Query: 298 VQDVVLSS--DGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSA 471 V V S D +S WD +++WDL T GH V +V S D S Sbjct: 151 VSCVRFSPNPDNLTFVSAGWDKAVKVWDLETFSLRTSHYGHTGYVSAVTISPDGSLCASG 210 Query: 472 SRDRTIKLWN 501 RD T+ LW+ Sbjct: 211 GRDGTLMLWD 220 Score = 48.1 bits (113), Expect = 2e-05 Identities = 37/129 (28%), Positives = 62/129 (48%), Gaps = 1/129 (0%) Frame = +1 Query: 118 GHNDVVTAIA-TPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGH 294 GH+D V+ + +P ++ VS+ DK++ VWDL + +S YG H Sbjct: 146 GHSDWVSCVRFSPNPDNLTFVSAGWDKAVKVWDL----ETFSLRTSHYG--------HTG 193 Query: 295 FVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSAS 474 +V V +S DG SG DG L LWDL+ +T + K ++ NR + A+ Sbjct: 194 YVSAVTISPDGSLCASGGRDGTLMLWDLNE--STHLYSLEAKANINALVFSPNRYWLCAA 251 Query: 475 RDRTIKLWN 501 +I++++ Sbjct: 252 TGSSIRIFD 260
>GBLP_TRYBR (P69104) Guanine nucleotide-binding protein beta subunit-like| protein (Activated protein kinase C receptor homolog) (Track) Length = 318 Score = 143 bits (361), Expect = 3e-34 Identities = 74/148 (50%), Positives = 99/148 (66%), Gaps = 2/148 (1%) Frame = +1 Query: 91 SLVYAGVMRGHNDVVTAIATPI--DNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGV 264 ++ Y G + GH VT++A P + + +VS+SRDK+LL W NP + + + S YG+ Sbjct: 2 AVAYEGQLTGHRGWVTSLACPQTPETATKVVSTSRDKTLLSWG-PNPDRHSSECS--YGL 58 Query: 265 PFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFS 444 P RRL GH FV DV LS++G FA+S SWD LRLW+L G +F+GH KDVLSVAFS Sbjct: 59 PDRRLEGHSAFVSDVALSNNGNFAVSASWDHSLRLWNLQNGQCQYKFLGHTKDVLSVAFS 118 Query: 445 IDNRQIVSASRDRTIKLWNTLGECKYTI 528 DNRQIVS RD +++WN GEC +T+ Sbjct: 119 PDNRQIVSGGRDNALRVWNVKGECMHTL 146 Score = 58.2 bits (139), Expect = 2e-08 Identities = 43/135 (31%), Positives = 59/135 (43%), Gaps = 3/135 (2%) Frame = +1 Query: 118 GHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHF 297 GH V ++A DN IVS RD +L VW++ T + H + Sbjct: 107 GHTKDVLSVAFSPDNRQ-IVSGGRDNALRVWNVKGECMHTLSRGA-----------HTDW 154 Query: 298 VQDVVLSS--DGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSA 471 V V S D +SG WD +++WDL+TG GH V SV S D S+ Sbjct: 155 VSCVRFSPSLDAPVIVSGGWDNLVKVWDLATGRLVTDLKGHTNYVTSVTVSPDGSLCASS 214 Query: 472 SRDRTIKLWN-TLGE 513 +D +LW+ T GE Sbjct: 215 DKDGVARLWDLTKGE 229
>GBLP_TRYBB (P69103) Guanine nucleotide-binding protein beta subunit-like| protein (Activated protein kinase C receptor homolog) Length = 318 Score = 143 bits (361), Expect = 3e-34 Identities = 74/148 (50%), Positives = 99/148 (66%), Gaps = 2/148 (1%) Frame = +1 Query: 91 SLVYAGVMRGHNDVVTAIATPI--DNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGV 264 ++ Y G + GH VT++A P + + +VS+SRDK+LL W NP + + + S YG+ Sbjct: 2 AVAYEGQLTGHRGWVTSLACPQTPETATKVVSTSRDKTLLSWG-PNPDRHSSECS--YGL 58 Query: 265 PFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFS 444 P RRL GH FV DV LS++G FA+S SWD LRLW+L G +F+GH KDVLSVAFS Sbjct: 59 PDRRLEGHSAFVSDVALSNNGNFAVSASWDHSLRLWNLQNGQCQYKFLGHTKDVLSVAFS 118 Query: 445 IDNRQIVSASRDRTIKLWNTLGECKYTI 528 DNRQIVS RD +++WN GEC +T+ Sbjct: 119 PDNRQIVSGGRDNALRVWNVKGECMHTL 146 Score = 58.2 bits (139), Expect = 2e-08 Identities = 43/135 (31%), Positives = 59/135 (43%), Gaps = 3/135 (2%) Frame = +1 Query: 118 GHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHF 297 GH V ++A DN IVS RD +L VW++ T + H + Sbjct: 107 GHTKDVLSVAFSPDNRQ-IVSGGRDNALRVWNVKGECMHTLSRGA-----------HTDW 154 Query: 298 VQDVVLSS--DGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSA 471 V V S D +SG WD +++WDL+TG GH V SV S D S+ Sbjct: 155 VSCVRFSPSLDAPVIVSGGWDNLVKVWDLATGRLVTDLKGHTNYVTSVTVSPDGSLCASS 214 Query: 472 SRDRTIKLWN-TLGE 513 +D +LW+ T GE Sbjct: 215 DKDGVARLWDLTKGE 229
>GBLP_YEAST (P38011) Guanine nucleotide-binding protein beta subunit-like| protein (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase) Length = 318 Score = 140 bits (352), Expect = 3e-33 Identities = 70/151 (46%), Positives = 94/151 (62%) Frame = +1 Query: 82 AQESLVYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYG 261 + E LV G + GHN VT++AT ++S+SRDK+L+ W LT Q ++G Sbjct: 2 SNEVLVLRGTLEGHNGWVTSLATSAGQPNLLLSASRDKTLISWKLTGDDQ-------KFG 54 Query: 262 VPFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAF 441 VP R GH H VQD L++DG +ALS SWD LRLWD++TG T +RFVGH+ DV+SV Sbjct: 55 VPVRSFKGHSHIVQDCTLTADGAYALSASWDKTLRLWDVATGETYQRFVGHKSDVMSVDI 114 Query: 442 SIDNRQIVSASRDRTIKLWNTLGECKYTIGG 534 I+S SRD+TIK+W G+C T+ G Sbjct: 115 DKKASMIISGSRDKTIKVWTIKGQCLATLLG 145 Score = 50.1 bits (118), Expect = 4e-06 Identities = 38/135 (28%), Positives = 58/135 (42%), Gaps = 7/135 (5%) Frame = +1 Query: 118 GHNDVVTAIATPIDN-SPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGH 294 GH V ++ ID + I+S SRDK++ VW + AT L GH Sbjct: 104 GHKSDVMSV--DIDKKASMIISGSRDKTIKVWTIKGQCLAT-------------LLGHND 148 Query: 295 FVQDVVL------SSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNR 456 +V V + D +S D ++ W+L+ F+GH ++ ++ S D Sbjct: 149 WVSQVRVVPNEKADDDSVTIISAGNDKMVKAWNLNQFQIEADFIGHNSNINTLTASPDGT 208 Query: 457 QIVSASRDRTIKLWN 501 I SA +D I LWN Sbjct: 209 LIASAGKDGEIMLWN 223 Score = 45.8 bits (107), Expect = 8e-05 Identities = 38/133 (28%), Positives = 60/133 (45%), Gaps = 5/133 (3%) Frame = +1 Query: 118 GHNDVVTAIAT-----PIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLT 282 GHND V+ + D+S I+S+ DK + W+L N Q D Sbjct: 145 GHNDWVSQVRVVPNEKADDDSVTIISAGNDKMVKAWNL-NQFQIEAD-----------FI 192 Query: 283 GHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQI 462 GH + + S DG S DGE+ LW+L+ + + +V S+AFS NR Sbjct: 193 GHNSNINTLTASPDGTLIASAGKDGEIMLWNLA-AKKAMYTLSAQDEVFSLAFS-PNRYW 250 Query: 463 VSASRDRTIKLWN 501 ++A+ IK+++ Sbjct: 251 LAAATATGIKVFS 263
>GBLP_LEIMA (Q25306) Guanine nucleotide-binding protein beta subunit-like| protein (Antigen LACK) Length = 312 Score = 121 bits (304), Expect = 1e-27 Identities = 65/143 (45%), Positives = 90/143 (62%), Gaps = 2/143 (1%) Frame = +1 Query: 100 YAGVMRGHNDVVTAIATPIDNSPFI--VSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFR 273 Y G ++GH VT++A P +I VS+SRD +++ W NP + + D S+YG+P Sbjct: 3 YEGHLKGHRGWVTSLACPQQAGSYIKVVSTSRDGTVISWK-ANPDRHSVD--SDYGLPNH 59 Query: 274 RLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDN 453 RL GH FV V L+ +AL+ SWD +R+WDL G R+F+ H KDVL+VAFS D+ Sbjct: 60 RLEGHTGFVSCVSLAHATDYALTASWDRSIRMWDLRNGQCQRKFLKHTKDVLAVAFSPDD 119 Query: 454 RQIVSASRDRTIKLWNTLGECKY 522 R IVSA RD I++WN GEC + Sbjct: 120 RLIVSAGRDNVIRVWNVAGECMH 142 Score = 59.3 bits (142), Expect = 7e-09 Identities = 40/129 (31%), Positives = 63/129 (48%), Gaps = 1/129 (0%) Frame = +1 Query: 118 GHNDVVTAIA-TPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGH 294 GH D V++I +P P +VS S D ++ VW++ G R L GH + Sbjct: 148 GHEDWVSSICFSPSLEHPIVVSGSWDNTIKVWNVNG------------GKCERTLKGHSN 195 Query: 295 FVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSAS 474 +V V +S DG SG DG LWDLSTG + + E + + FS NR + + Sbjct: 196 YVSTVTVSPDGSLCASGGKDGAALLWDLSTGEQLFK-INVESPINQIGFS-PNRFWMCVA 253 Query: 475 RDRTIKLWN 501 +R++ +++ Sbjct: 254 TERSLSVYD 262
>GBLP_LEIIN (P62884) Guanine nucleotide-binding protein beta subunit-like| protein (Antigen LACK) (LiP36) (p36Li) Length = 312 Score = 121 bits (303), Expect = 1e-27 Identities = 65/143 (45%), Positives = 89/143 (62%), Gaps = 2/143 (1%) Frame = +1 Query: 100 YAGVMRGHNDVVTAIATPIDNSPFI--VSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFR 273 Y G ++GH VT++A P +I VS+SRD + + W NP + + D S+YG+P Sbjct: 3 YEGHLKGHRGWVTSLACPQQAGSYIKVVSTSRDGTAISWK-ANPDRHSVD--SDYGLPSH 59 Query: 274 RLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDN 453 RL GH FV V L+ +AL+ SWD +R+WDL G R+F+ H KDVL+VAFS D+ Sbjct: 60 RLEGHTGFVSCVSLAHATDYALTASWDRSIRMWDLRNGQCQRKFLKHTKDVLAVAFSPDD 119 Query: 454 RQIVSASRDRTIKLWNTLGECKY 522 R IVSA RD I++WN GEC + Sbjct: 120 RLIVSAGRDNVIRVWNVAGECMH 142 Score = 60.8 bits (146), Expect = 2e-09 Identities = 41/129 (31%), Positives = 64/129 (49%), Gaps = 1/129 (0%) Frame = +1 Query: 118 GHNDVVTAIA-TPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGH 294 GH D V++I +P P +VS S D ++ VW++ G R L GH + Sbjct: 148 GHEDWVSSICFSPSLEHPIVVSGSWDNTIKVWNVNG------------GKCERTLKGHSN 195 Query: 295 FVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSAS 474 +V V +S DG SG DG LWDLSTG + + E + +AFS NR + + Sbjct: 196 YVSTVTVSPDGSLCASGGKDGAALLWDLSTGEQLFK-INVESPINQIAFS-PNRFWMCVA 253 Query: 475 RDRTIKLWN 501 +R++ +++ Sbjct: 254 TERSLSVYD 262
>GBLP_LEICH (P62883) Guanine nucleotide-binding protein beta subunit-like| protein (Antigen LACK) Length = 312 Score = 121 bits (303), Expect = 1e-27 Identities = 65/143 (45%), Positives = 89/143 (62%), Gaps = 2/143 (1%) Frame = +1 Query: 100 YAGVMRGHNDVVTAIATPIDNSPFI--VSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFR 273 Y G ++GH VT++A P +I VS+SRD + + W NP + + D S+YG+P Sbjct: 3 YEGHLKGHRGWVTSLACPQQAGSYIKVVSTSRDGTAISWK-ANPDRHSVD--SDYGLPSH 59 Query: 274 RLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDN 453 RL GH FV V L+ +AL+ SWD +R+WDL G R+F+ H KDVL+VAFS D+ Sbjct: 60 RLEGHTGFVSCVSLAHATDYALTASWDRSIRMWDLRNGQCQRKFLKHTKDVLAVAFSPDD 119 Query: 454 RQIVSASRDRTIKLWNTLGECKY 522 R IVSA RD I++WN GEC + Sbjct: 120 RLIVSAGRDNVIRVWNVAGECMH 142 Score = 60.8 bits (146), Expect = 2e-09 Identities = 41/129 (31%), Positives = 64/129 (49%), Gaps = 1/129 (0%) Frame = +1 Query: 118 GHNDVVTAIA-TPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGH 294 GH D V++I +P P +VS S D ++ VW++ G R L GH + Sbjct: 148 GHEDWVSSICFSPSLEHPIVVSGSWDNTIKVWNVNG------------GKCERTLKGHSN 195 Query: 295 FVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSAS 474 +V V +S DG SG DG LWDLSTG + + E + +AFS NR + + Sbjct: 196 YVSTVTVSPDGSLCASGGKDGAALLWDLSTGEQLFK-INVESPINQIAFS-PNRFWMCVA 253 Query: 475 RDRTIKLWN 501 +R++ +++ Sbjct: 254 TERSLSVYD 262
>HETE1_PODAN (Q00808) Vegetatible incompatibility protein HET-E-1| Length = 1356 Score = 92.4 bits (228), Expect = 7e-19 Identities = 54/145 (37%), Positives = 76/145 (52%), Gaps = 1/145 (0%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 + GH V ++A D + S S DK++ +WD + G + L GHG Sbjct: 879 LEGHGGSVWSVAFSPDRER-VASGSDDKTIKIWDAAS------------GTCTQTLEGHG 925 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSA 471 VQ V S DGQ SGS D +++WD ++G T+ GH VLSVAFS D +++ S Sbjct: 926 GRVQSVAFSPDGQRVASGSDDHTIKIWDAASGTCTQTLEGHGSSVLSVAFSPDGQRVASG 985 Query: 472 SRDRTIKLWNTL-GECKYTIGGDLG 543 S D+TIK+W+T G C T+ G G Sbjct: 986 SGDKTIKIWDTASGTCTQTLEGHGG 1010 Score = 90.9 bits (224), Expect = 2e-18 Identities = 53/145 (36%), Positives = 76/145 (52%), Gaps = 1/145 (0%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 + GH D V ++A D + S S D ++ +WD + G + L GHG Sbjct: 1089 LEGHGDSVWSVAFSPDGQR-VASGSIDGTIKIWDAAS------------GTCTQTLEGHG 1135 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSA 471 +V V S DGQ SGS DG +++WD ++G T+ GH V SVAFS D +++ S Sbjct: 1136 GWVHSVAFSPDGQRVASGSIDGTIKIWDAASGTCTQTLEGHGGWVQSVAFSPDGQRVASG 1195 Query: 472 SRDRTIKLWNTL-GECKYTIGGDLG 543 S D+TIK+W+T G C T+ G G Sbjct: 1196 SSDKTIKIWDTASGTCTQTLEGHGG 1220 Score = 87.8 bits (216), Expect = 2e-17 Identities = 53/145 (36%), Positives = 74/145 (51%), Gaps = 1/145 (0%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 + GH V ++A D + S S DK++ +WD + G + L GHG Sbjct: 1005 LEGHGGSVWSVAFSPDGQR-VASGSDDKTIKIWDTAS------------GTCTQTLEGHG 1051 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSA 471 +VQ VV S DGQ SGS D +++WD +G T+ GH V SVAFS D +++ S Sbjct: 1052 GWVQSVVFSPDGQRVASGSDDHTIKIWDAVSGTCTQTLEGHGDSVWSVAFSPDGQRVASG 1111 Query: 472 SRDRTIKLWNTL-GECKYTIGGDLG 543 S D TIK+W+ G C T+ G G Sbjct: 1112 SIDGTIKIWDAASGTCTQTLEGHGG 1136 Score = 85.9 bits (211), Expect = 7e-17 Identities = 51/145 (35%), Positives = 73/145 (50%), Gaps = 1/145 (0%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 + GH V ++A D + S S D ++ +WD + G + L GHG Sbjct: 921 LEGHGGRVQSVAFSPDGQR-VASGSDDHTIKIWDAAS------------GTCTQTLEGHG 967 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSA 471 V V S DGQ SGS D +++WD ++G T+ GH V SVAFS D +++ S Sbjct: 968 SSVLSVAFSPDGQRVASGSGDKTIKIWDTASGTCTQTLEGHGGSVWSVAFSPDGQRVASG 1027 Query: 472 SRDRTIKLWNTL-GECKYTIGGDLG 543 S D+TIK+W+T G C T+ G G Sbjct: 1028 SDDKTIKIWDTASGTCTQTLEGHGG 1052 Score = 84.0 bits (206), Expect = 3e-16 Identities = 50/140 (35%), Positives = 72/140 (51%), Gaps = 1/140 (0%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 + GH V ++A D + S S D ++ +WD + G + L GHG Sbjct: 1131 LEGHGGWVHSVAFSPDGQR-VASGSIDGTIKIWDAAS------------GTCTQTLEGHG 1177 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSA 471 +VQ V S DGQ SGS D +++WD ++G T+ GH V SVAFS D +++ S Sbjct: 1178 GWVQSVAFSPDGQRVASGSSDKTIKIWDTASGTCTQTLEGHGGWVQSVAFSPDGQRVASG 1237 Query: 472 SRDRTIKLWNTL-GECKYTI 528 S D TIK+W+T G C T+ Sbjct: 1238 SSDNTIKIWDTASGTCTQTL 1257 Score = 82.4 bits (202), Expect = 8e-16 Identities = 49/142 (34%), Positives = 71/142 (50%), Gaps = 1/142 (0%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 + GH V ++A D + S S DK++ +WD + G + L GHG Sbjct: 963 LEGHGSSVLSVAFSPDGQR-VASGSGDKTIKIWDTAS------------GTCTQTLEGHG 1009 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSA 471 V V S DGQ SGS D +++WD ++G T+ GH V SV FS D +++ S Sbjct: 1010 GSVWSVAFSPDGQRVASGSDDKTIKIWDTASGTCTQTLEGHGGWVQSVVFSPDGQRVASG 1069 Query: 472 SRDRTIKLWNTL-GECKYTIGG 534 S D TIK+W+ + G C T+ G Sbjct: 1070 SDDHTIKIWDAVSGTCTQTLEG 1091 Score = 81.3 bits (199), Expect = 2e-15 Identities = 50/145 (34%), Positives = 71/145 (48%), Gaps = 1/145 (0%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 + GH V ++ D + S S D ++ +WD + G + L GHG Sbjct: 1047 LEGHGGWVQSVVFSPDGQR-VASGSDDHTIKIWDAVS------------GTCTQTLEGHG 1093 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSA 471 V V S DGQ SGS DG +++WD ++G T+ GH V SVAFS D +++ S Sbjct: 1094 DSVWSVAFSPDGQRVASGSIDGTIKIWDAASGTCTQTLEGHGGWVHSVAFSPDGQRVASG 1153 Query: 472 SRDRTIKLWNTL-GECKYTIGGDLG 543 S D TIK+W+ G C T+ G G Sbjct: 1154 SIDGTIKIWDAASGTCTQTLEGHGG 1178 Score = 80.9 bits (198), Expect = 2e-15 Identities = 48/142 (33%), Positives = 70/142 (49%), Gaps = 1/142 (0%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 + GH V ++A D + S S DK++ +WD + G + L GHG Sbjct: 837 LEGHGSSVLSVAFSADGQR-VASGSDDKTIKIWDTAS------------GTGTQTLEGHG 883 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSA 471 V V S D + SGS D +++WD ++G T+ GH V SVAFS D +++ S Sbjct: 884 GSVWSVAFSPDRERVASGSDDKTIKIWDAASGTCTQTLEGHGGRVQSVAFSPDGQRVASG 943 Query: 472 SRDRTIKLWNTL-GECKYTIGG 534 S D TIK+W+ G C T+ G Sbjct: 944 SDDHTIKIWDAASGTCTQTLEG 965 Score = 75.9 bits (185), Expect = 7e-14 Identities = 40/99 (40%), Positives = 56/99 (56%), Gaps = 1/99 (1%) Frame = +1 Query: 250 SEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVL 429 +E+ + L GHG V V S+DGQ SGS D +++WD ++G T+ GH V Sbjct: 828 AEWNACTQTLEGHGSSVLSVAFSADGQRVASGSDDKTIKIWDTASGTGTQTLEGHGGSVW 887 Query: 430 SVAFSIDNRQIVSASRDRTIKLWNTL-GECKYTIGGDLG 543 SVAFS D ++ S S D+TIK+W+ G C T+ G G Sbjct: 888 SVAFSPDRERVASGSDDKTIKIWDAASGTCTQTLEGHGG 926 Score = 45.4 bits (106), Expect = 1e-04 Identities = 20/52 (38%), Positives = 30/52 (57%) Frame = +1 Query: 349 WDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNT 504 W + + + T+ GH VLSVAFS D +++ S S D+TIK+W+T Sbjct: 819 WISTISVVEAEWNACTQTLEGHGSSVLSVAFSADGQRVASGSDDKTIKIWDT 870
>Y2800_ANASP (Q8YTC2) Hypothetical WD-repeat protein alr2800| Length = 1258 Score = 89.0 bits (219), Expect = 8e-18 Identities = 51/139 (36%), Positives = 77/139 (55%), Gaps = 2/139 (1%) Frame = +1 Query: 106 GVMRGH-NDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLT 282 G++RGH N V +AI +P N I + S D+++ +WD + G + LT Sbjct: 1098 GILRGHSNRVYSAIFSP--NGEIIATCSTDQTVKIWDW------------QQGKCLKTLT 1143 Query: 283 GHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQI 462 GH ++V D+ S DG+ S S D +R+WD++TG +GH V SVAFS D + Sbjct: 1144 GHTNWVFDIAFSPDGKILASASHDQTVRIWDVNTGKCHHICIGHTHLVSSVAFSPDGEVV 1203 Query: 463 VSASRDRTIKLWNT-LGEC 516 S S+D+T+++WN GEC Sbjct: 1204 ASGSQDQTVRIWNVKTGEC 1222 Score = 83.2 bits (204), Expect = 5e-16 Identities = 45/130 (34%), Positives = 71/130 (54%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 + GH D V +A D + + SS+ D ++ +WD++ G R L H Sbjct: 764 LTGHTDWVRCVAFSPDGNT-LASSAADHTIKLWDVSQ------------GKCLRTLKSHT 810 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSA 471 +V+ V S+DGQ SGS D +++W+ TG + ++GH V S+A+S D++ +VS Sbjct: 811 GWVRSVAFSADGQTLASGSGDRTIKIWNYHTGECLKTYIGHTNSVYSIAYSPDSKILVSG 870 Query: 472 SRDRTIKLWN 501 S DRTIKLW+ Sbjct: 871 SGDRTIKLWD 880 Score = 79.3 bits (194), Expect = 7e-15 Identities = 51/142 (35%), Positives = 71/142 (50%), Gaps = 1/142 (0%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 + GH V ++A D + S+S DK++ +WD+ + G + LTGH Sbjct: 722 LTGHEHEVFSVAFHPDGET-LASASGDKTIKLWDIQD------------GTCLQTLTGHT 768 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSA 471 +V+ V S DG S + D ++LWD+S G R H V SVAFS D + + S Sbjct: 769 DWVRCVAFSPDGNTLASSAADHTIKLWDVSQGKCLRTLKSHTGWVRSVAFSADGQTLASG 828 Query: 472 SRDRTIKLWN-TLGECKYTIGG 534 S DRTIK+WN GEC T G Sbjct: 829 SGDRTIKIWNYHTGECLKTYIG 850 Score = 73.6 bits (179), Expect = 4e-13 Identities = 45/146 (30%), Positives = 69/146 (47%), Gaps = 1/146 (0%) Frame = +1 Query: 109 VMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 + RGH++ V + D + S D+++ +W + + GV + LTGH Sbjct: 679 ICRGHSNWVRFVVFSPDGE-ILASCGADENVKLWSVRD------------GVCIKTLTGH 725 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVS 468 H V V DG+ S S D ++LWD+ G + GH V VAFS D + S Sbjct: 726 EHEVFSVAFHPDGETLASASGDKTIKLWDIQDGTCLQTLTGHTDWVRCVAFSPDGNTLAS 785 Query: 469 ASRDRTIKLWN-TLGECKYTIGGDLG 543 ++ D TIKLW+ + G+C T+ G Sbjct: 786 SAADHTIKLWDVSQGKCLRTLKSHTG 811 Score = 68.6 bits (166), Expect = 1e-11 Identities = 42/140 (30%), Positives = 70/140 (50%), Gaps = 1/140 (0%) Frame = +1 Query: 100 YAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRL 279 Y + GH D + IA D S + S+S D S+ +W+++ G F+ L Sbjct: 970 YISSLEGHTDFIYGIAFSPD-SQTLASASTDSSVRLWNIST------------GQCFQIL 1016 Query: 280 TGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQ 459 H +V VV G+ +GS D ++LW++STG + H +L +A+S D + Sbjct: 1017 LEHTDWVYAVVFHPQGKIIATGSADCTVKLWNISTGQCLKTLSEHSDKILGMAWSPDGQL 1076 Query: 460 IVSASRDRTIKLWN-TLGEC 516 + SAS D++++LW+ G C Sbjct: 1077 LASASADQSVRLWDCCTGRC 1096 Score = 67.8 bits (164), Expect = 2e-11 Identities = 38/136 (27%), Positives = 65/136 (47%), Gaps = 1/136 (0%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 ++ H V ++A D + S S D+++ +W+ G + GH Sbjct: 806 LKSHTGWVRSVAFSADGQT-LASGSGDRTIKIWNYHT------------GECLKTYIGHT 852 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSA 471 + V + S D + +SGS D ++LWD T + + GH +V SVAFS D + + Sbjct: 853 NSVYSIAYSPDSKILVSGSGDRTIKLWDCQTHICIKTLHGHTNEVCSVAFSPDGQTLACV 912 Query: 472 SRDRTIKLWN-TLGEC 516 S D++++LWN G+C Sbjct: 913 SLDQSVRLWNCRTGQC 928 Score = 67.0 bits (162), Expect = 3e-11 Identities = 44/128 (34%), Positives = 63/128 (49%) Frame = +1 Query: 118 GHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHF 297 GH + V +IA D S +VS S D+++ +WD I + L GH + Sbjct: 850 GHTNSVYSIAYSPD-SKILVSGSGDRTIKLWDCQTHIC------------IKTLHGHTNE 896 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASR 477 V V S DGQ S D +RLW+ TG + + G+ L VAFS D + + S S Sbjct: 897 VCSVAFSPDGQTLACVSLDQSVRLWNCRTGQCLKAWYGNTDWALPVAFSPDRQILASGSN 956 Query: 478 DRTIKLWN 501 D+T+KLW+ Sbjct: 957 DKTVKLWD 964 Score = 65.9 bits (159), Expect = 7e-11 Identities = 42/132 (31%), Positives = 62/132 (46%), Gaps = 4/132 (3%) Frame = +1 Query: 145 ATPIDNSP---FIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVL 315 A P+ SP + S S DK++ +WD + G L GH F+ + Sbjct: 939 ALPVAFSPDRQILASGSNDKTVKLWDW------------QTGKYISSLEGHTDFIYGIAF 986 Query: 316 SSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKL 495 S D Q S S D +RLW++STG + + H V +V F + I + S D T+KL Sbjct: 987 SPDSQTLASASTDSSVRLWNISTGQCFQILLEHTDWVYAVVFHPQGKIIATGSADCTVKL 1046 Query: 496 WN-TLGECKYTI 528 WN + G+C T+ Sbjct: 1047 WNISTGQCLKTL 1058 Score = 40.0 bits (92), Expect = 0.004 Identities = 23/80 (28%), Positives = 35/80 (43%), Gaps = 1/80 (1%) Frame = +1 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASR 477 + S +GQ + D +R+W++ +G GH V V FS D + S Sbjct: 645 ILSAAFSPEGQLLATCDTDCHVRVWEVKSGKLLLICRGHSNWVRFVVFSPDGEILASCGA 704 Query: 478 DRTIKLWNTL-GECKYTIGG 534 D +KLW+ G C T+ G Sbjct: 705 DENVKLWSVRDGVCIKTLTG 724
>TUP11_SCHPO (Q09715) Transcriptional repressor tup11| Length = 614 Score = 84.0 bits (206), Expect = 3e-16 Identities = 47/130 (36%), Positives = 68/130 (52%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 + GH + V +IA D+S ++S S DK++ VW+L G+ TGH Sbjct: 480 LEGHKESVYSIAFSPDSS-ILLSGSLDKTIKVWELQATRSVGLSAIKPEGICKATYTGHT 538 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSA 471 FV V +S D ++ LSGS D ++ WDL TG + GH+ V+SV FS D RQ S Sbjct: 539 DFVLSVAVSPDSRWGLSGSKDRSMQFWDLQTGQSYLTCQGHKNSVISVCFSPDGRQFASG 598 Query: 472 SRDRTIKLWN 501 S D ++W+ Sbjct: 599 SGDLRARIWS 608 Score = 67.8 bits (164), Expect = 2e-11 Identities = 32/75 (42%), Positives = 50/75 (66%), Gaps = 1/75 (1%) Frame = +1 Query: 295 FVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSAS 474 +V+ + S DG++ ++G+ D +++LWDLST F GHE+D+ S+ FS + R IVS S Sbjct: 362 YVRTIAFSPDGKYLVTGTEDRQIKLWDLSTQKVRYVFSGHEQDIYSLDFSHNGRFIVSGS 421 Query: 475 RDRTIKLWNT-LGEC 516 DRT +LW+ G+C Sbjct: 422 GDRTARLWDVETGQC 436 Score = 62.8 bits (151), Expect = 6e-10 Identities = 43/135 (31%), Positives = 61/135 (45%), Gaps = 12/135 (8%) Frame = +1 Query: 133 VTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVV 312 VTAIA N FI S D+ + VW ++ G RL GH V + Sbjct: 446 VTAIAIS-PNDQFIAVGSLDQIIRVWSVS-------------GTLVERLEGHKESVYSIA 491 Query: 313 LSSDGQFALSGSWDGELRLWDLST------------GVTTRRFVGHEKDVLSVAFSIDNR 456 S D LSGS D +++W+L G+ + GH VLSVA S D+R Sbjct: 492 FSPDSSILLSGSLDKTIKVWELQATRSVGLSAIKPEGICKATYTGHTDFVLSVAVSPDSR 551 Query: 457 QIVSASRDRTIKLWN 501 +S S+DR+++ W+ Sbjct: 552 WGLSGSKDRSMQFWD 566 Score = 60.8 bits (146), Expect = 2e-09 Identities = 39/113 (34%), Positives = 57/113 (50%) Frame = +1 Query: 160 NSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFAL 339 N FIVS S D++ +WD+ Q E GV + +S + QF Sbjct: 413 NGRFIVSGSGDRTARLWDVETG-QCILKLEIENGVTA------------IAISPNDQFIA 459 Query: 340 SGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLW 498 GS D +R+W +S G R GH++ V S+AFS D+ ++S S D+TIK+W Sbjct: 460 VGSLDQIIRVWSVS-GTLVERLEGHKESVYSIAFSPDSSILLSGSLDKTIKVW 511 Score = 42.4 bits (98), Expect = 9e-04 Identities = 28/87 (32%), Positives = 41/87 (47%) Frame = +1 Query: 118 GHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHF 297 GH D V ++A D S + +S S+D+S+ WDL + G + GH + Sbjct: 536 GHTDFVLSVAVSPD-SRWGLSGSKDRSMQFWDL------------QTGQSYLTCQGHKNS 582 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDL 378 V V S DG+ SGS D R+W + Sbjct: 583 VISVCFSPDGRQFASGSGDLRARIWSI 609
>Y2124_ANASP (Q8YV57) Hypothetical WD-repeat protein all2124| Length = 1683 Score = 82.4 bits (202), Expect = 8e-16 Identities = 56/161 (34%), Positives = 75/161 (46%), Gaps = 1/161 (0%) Frame = +1 Query: 67 TTMAGAQESLVYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDT 246 TT+ A + + GH D V +I+ D I S S DK++ +W Sbjct: 1053 TTLQQALFEMQERNRLEGHKDGVISISISRDGQT-IASGSLDKTIKLW------------ 1099 Query: 247 SSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDV 426 S G FR L GH V V S DGQ SG D ++LW S G + GHE+ V Sbjct: 1100 -SRDGRLFRTLNGHEDAVYSVSFSPDGQTIASGGSDKTIKLWQTSDGTLLKTITGHEQTV 1158 Query: 427 LSVAFSIDNRQIVSASRDRTIKLWNTL-GECKYTIGGDLGG 546 +V FS D + + SAS D +IKLW+T G+ T+ G G Sbjct: 1159 NNVYFSPDGKNLASASSDHSIKLWDTTSGQLLMTLTGHSAG 1199 Score = 74.3 bits (181), Expect = 2e-13 Identities = 40/130 (30%), Positives = 64/130 (49%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 + GH D V +++ D I S DK++ +W ++ G + +TGH Sbjct: 1109 LNGHEDAVYSVSFSPDGQT-IASGGSDKTIKLWQTSD------------GTLLKTITGHE 1155 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSA 471 V +V S DG+ S S D ++LWD ++G GH V++V FS D + I + Sbjct: 1156 QTVNNVYFSPDGKNLASASSDHSIKLWDTTSGQLLMTLTGHSAGVITVRFSPDGQTIAAG 1215 Query: 472 SRDRTIKLWN 501 S D+T+KLW+ Sbjct: 1216 SEDKTVKLWH 1225 Score = 72.0 bits (175), Expect = 1e-12 Identities = 49/145 (33%), Positives = 66/145 (45%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 + GH+ V + D I + S DK++ +W QD G + L GH Sbjct: 1193 LTGHSAGVITVRFSPDGQT-IAAGSEDKTVKLWH-------RQD-----GKLLKTLNGHQ 1239 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSA 471 +V + S DG+ S S D ++LW ++ G + GH V V FS D + I SA Sbjct: 1240 DWVNSLSFSPDGKTLASASADKTIKLWRIADGKLVKTLKGHNDSVWDVNFSSDGKAIASA 1299 Query: 472 SRDRTIKLWNTLGECKYTIGGDLGG 546 SRD TIKLWN G T G GG Sbjct: 1300 SRDNTIKLWNRHGIELETFTGHSGG 1324 Score = 68.2 bits (165), Expect = 2e-11 Identities = 45/139 (32%), Positives = 62/139 (44%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 ++GH D V ++ D I S+S DK++ +WD S G + L H Sbjct: 1484 LKGHTDEVFWVSFSPDGK-IIASASADKTIRLWD------------SFSGNLIKSLPAHN 1530 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSA 471 V V + DG S S D ++LW G F GH V S +FS D R I SA Sbjct: 1531 DLVYSVNFNPDGSMLASTSADKTVKLWRSHDGHLLHTFSGHSNVVYSSSFSPDGRYIASA 1590 Query: 472 SRDRTIKLWNTLGECKYTI 528 S D+T+K+W G T+ Sbjct: 1591 SEDKTVKIWQIDGHLLTTL 1609 Score = 67.0 bits (162), Expect = 3e-11 Identities = 43/129 (33%), Positives = 63/129 (48%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 + GH D V +++ D + S+S DK++ +W + + G + L GH Sbjct: 1235 LNGHQDWVNSLSFSPDGKT-LASASADKTIKLWRIAD------------GKLVKTLKGHN 1281 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSA 471 V DV SSDG+ S S D ++LW+ G+ F GH V +V F D+ I SA Sbjct: 1282 DSVWDVNFSSDGKAIASASRDNTIKLWNRH-GIELETFTGHSGGVYAVNFLPDSNIIASA 1340 Query: 472 SRDRTIKLW 498 S D TI+LW Sbjct: 1341 SLDNTIRLW 1349 Score = 66.2 bits (160), Expect = 6e-11 Identities = 37/111 (33%), Positives = 59/111 (53%) Frame = +1 Query: 172 IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSW 351 I S++ DK++ +W + + G + L GH + V V S DG+ S S Sbjct: 1419 IASANADKTVKIWRVRD------------GKALKTLIGHDNEVNKVNFSPDGKTLASASR 1466 Query: 352 DGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNT 504 D ++LW++S G + GH +V V+FS D + I SAS D+TI+LW++ Sbjct: 1467 DNTVKLWNVSDGKFKKTLKGHTDEVFWVSFSPDGKIIASASADKTIRLWDS 1517 Score = 59.7 bits (143), Expect = 5e-09 Identities = 42/140 (30%), Positives = 65/140 (46%), Gaps = 1/140 (0%) Frame = +1 Query: 118 GHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHF 297 GH++ V + D + S+SRD ++ +W++++ G + L GH Sbjct: 1444 GHDNEVNKVNFSPDGKT-LASASRDNTVKLWNVSD------------GKFKKTLKGHTDE 1490 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASR 477 V V S DG+ S S D +RLWD +G + H V SV F+ D + S S Sbjct: 1491 VFWVSFSPDGKIIASASADKTIRLWDSFSGNLIKSLPAHNDLVYSVNFNPDGSMLASTSA 1550 Query: 478 DRTIKLWNTL-GECKYTIGG 534 D+T+KLW + G +T G Sbjct: 1551 DKTVKLWRSHDGHLLHTFSG 1570 Score = 59.7 bits (143), Expect = 5e-09 Identities = 44/169 (26%), Positives = 74/169 (43%), Gaps = 30/169 (17%) Frame = +1 Query: 118 GHNDVVTAIATPIDNSPFIVSSSRDKSLLVWD--LTNPIQATQDTSSEYGVPF------- 270 GH+ V A+ + +S I S+S D ++ +W L +P++ S Y V F Sbjct: 1320 GHSGGVYAVNF-LPDSNIIASASLDNTIRLWQRPLISPLEVLAGNSGVYAVSFLHDGSII 1378 Query: 271 --------------------RRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGV 390 + L G+ + + + G S + D +++W + G Sbjct: 1379 ATAGADGNIQLWHSQDGSLLKTLPGN-KAIYGISFTPQGDLIASANADKTVKIWRVRDGK 1437 Query: 391 TTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNTL-GECKYTIGG 534 + +GH+ +V V FS D + + SASRD T+KLWN G+ K T+ G Sbjct: 1438 ALKTLIGHDNEVNKVNFSPDGKTLASASRDNTVKLWNVSDGKFKKTLKG 1486 Score = 36.6 bits (83), Expect = 0.049 Identities = 23/85 (27%), Positives = 39/85 (45%) Frame = +1 Query: 118 GHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHF 297 GH++VV + + D +I S+S DK++ +W + + T L H Sbjct: 1570 GHSNVVYSSSFSPDGR-YIASASEDKTVKIWQIDGHLLTT-------------LPQHQAG 1615 Query: 298 VQDVVLSSDGQFALSGSWDGELRLW 372 V + S DG+ +SGS D ++W Sbjct: 1616 VMSAIFSPDGKTLISGSLDTTTKIW 1640
>PKWA_THECU (P49695) Probable serine/threonine-protein kinase pkwA (EC| 2.7.11.1) Length = 742 Score = 82.0 bits (201), Expect = 1e-15 Identities = 48/130 (36%), Positives = 67/130 (51%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 + GH D V A+A D + + S S D ++ +WD+ ++E F GH Sbjct: 497 LEGHTDWVRAVAFSPDGA-LLASGSDDATVRLWDVA---------AAEERAVFE---GHT 543 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSA 471 H+V D+ S DG SGS DG RLW+++TG GH V +VAFS D + S Sbjct: 544 HYVLDIAFSPDGSMVASGSRDGTARLWNVATGTEHAVLKGHTDYVYAVAFSPDGSMVASG 603 Query: 472 SRDRTIKLWN 501 SRD TI+LW+ Sbjct: 604 SRDGTIRLWD 613 Score = 73.9 bits (180), Expect = 3e-13 Identities = 55/161 (34%), Positives = 79/161 (49%), Gaps = 1/161 (0%) Frame = +1 Query: 55 SLRHTTMAGAQESLVYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQA 234 ++R +A A+E V+ GH V IA D S + S SRD + +W++ Sbjct: 524 TVRLWDVAAAEERAVF----EGHTHYVLDIAFSPDGS-MVASGSRDGTARLWNVA----- 573 Query: 235 TQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGH 414 T +E+ V L GH +V V S DG SGS DG +RLWD++TG Sbjct: 574 ---TGTEHAV----LKGHTDYVYAVAFSPDGSMVASGSRDGTIRLWDVATGKERDVLQAP 626 Query: 415 EKDVLSVAFSIDNRQIVSASRDRTIKLWNTL-GECKYTIGG 534 ++V+S+AFS D +V S D T+ LW+ GE +T G Sbjct: 627 AENVVSLAFSPDGSMLVHGS-DSTVHLWDVASGEALHTFEG 666 Score = 73.2 bits (178), Expect = 5e-13 Identities = 48/139 (34%), Positives = 69/139 (49%) Frame = +1 Query: 109 VMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 V++GH D V A+A D S + S SRD ++ +WD+ T E V L Sbjct: 580 VLKGHTDYVYAVAFSPDGS-MVASGSRDGTIRLWDVA--------TGKERDV----LQAP 626 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVS 468 V + S DG + GS D + LWD+++G F GH V +VAFS D + S Sbjct: 627 AENVVSLAFSPDGSMLVHGS-DSTVHLWDVASGEALHTFEGHTDWVRAVAFSPDGALLAS 685 Query: 469 ASRDRTIKLWNTLGECKYT 525 S DRTI+LW+ + ++T Sbjct: 686 GSDDRTIRLWDVAAQEEHT 704 Score = 71.6 bits (174), Expect = 1e-12 Identities = 50/159 (31%), Positives = 68/159 (42%) Frame = +1 Query: 25 LHRTPRKP*RSLRHTTMAGAQESLVYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLL 204 L TP +P S + A E L ++ + V +P + S DK + Sbjct: 428 LPETPLRPDSSTAPSESADPHE-LNEPRILTTDREAVAVAFSP--GGSLLAGGSGDKLIH 484 Query: 205 VWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLST 384 VWD+ + G L GH +V+ V S DG SGS D +RLWD++ Sbjct: 485 VWDVAS------------GDELHTLEGHTDWVRAVAFSPDGALLASGSDDATVRLWDVAA 532 Query: 385 GVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN 501 F GH VL +AFS D + S SRD T +LWN Sbjct: 533 AEERAVFEGHTHYVLDIAFSPDGSMVASGSRDGTARLWN 571 Score = 40.8 bits (94), Expect = 0.003 Identities = 26/89 (29%), Positives = 40/89 (44%) Frame = +1 Query: 118 GHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHF 297 GH D V A+A D + + S S D+++ +WD+ + T L GH Sbjct: 666 GHTDWVRAVAFSPDGA-LLASGSDDRTIRLWDVAAQEEHTT------------LEGHTEP 712 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLST 384 V V +G S S DG +R+W ++T Sbjct: 713 VHSVAFHPEGTTLASASEDGTIRIWPIAT 741
>YY46_ANASP (Q8YRI1) Hypothetical WD-repeat protein alr3466| Length = 1526 Score = 78.2 bits (191), Expect = 1e-14 Identities = 49/141 (34%), Positives = 73/141 (51%), Gaps = 1/141 (0%) Frame = +1 Query: 115 RGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGH 294 +GH V ++ D S + S S DK++ +WD++ SS+ F+ GH + Sbjct: 1239 QGHTSWVNSVVFNPDGS-MLASGSSDKTVRLWDIS---------SSKCLHTFQ---GHTN 1285 Query: 295 FVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSAS 474 +V V + DG SGS D +RLW++S+ F GH V SV FS D + S S Sbjct: 1286 WVNSVAFNPDGSMLASGSGDQTVRLWEISSSKCLHTFQGHTSWVSSVTFSPDGTMLASGS 1345 Query: 475 RDRTIKLWN-TLGECKYTIGG 534 D+T++LW+ + GEC YT G Sbjct: 1346 DDQTVRLWSISSGECLYTFLG 1366 Score = 77.8 bits (190), Expect = 2e-14 Identities = 49/143 (34%), Positives = 75/143 (52%), Gaps = 1/143 (0%) Frame = +1 Query: 109 VMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 + +GH V ++A +D S + + S D+++ +WD++ SS+ F+ GH Sbjct: 985 IFQGHTGWVYSVAFNLDGS-MLATGSGDQTVRLWDIS---------SSQCFYIFQ---GH 1031 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVS 468 V+ VV SSDG SGS D +RLWD+S+G GH V SV FS D + S Sbjct: 1032 TSCVRSVVFSSDGAMLASGSDDQTVRLWDISSGNCLYTLQGHTSCVRSVVFSPDGAMLAS 1091 Query: 469 ASRDRTIKLWN-TLGECKYTIGG 534 D+ ++LW+ + G C YT+ G Sbjct: 1092 GGDDQIVRLWDISSGNCLYTLQG 1114 Score = 75.5 bits (184), Expect = 9e-14 Identities = 49/141 (34%), Positives = 76/141 (53%), Gaps = 1/141 (0%) Frame = +1 Query: 115 RGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGH 294 +GH + V ++A D S + S S D+++ +W+++ SS+ F+ GH Sbjct: 1281 QGHTNWVNSVAFNPDGS-MLASGSGDQTVRLWEIS---------SSKCLHTFQ---GHTS 1327 Query: 295 FVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSAS 474 +V V S DG SGS D +RLW +S+G F+GH V SV FS D + S S Sbjct: 1328 WVSSVTFSPDGTMLASGSDDQTVRLWSISSGECLYTFLGHTNWVGSVIFSPDGAILASGS 1387 Query: 475 RDRTIKLWN-TLGECKYTIGG 534 D+T++LW+ + G+C YT+ G Sbjct: 1388 GDQTVRLWSISSGKCLYTLQG 1408 Score = 74.3 bits (181), Expect = 2e-13 Identities = 53/166 (31%), Positives = 78/166 (46%), Gaps = 2/166 (1%) Frame = +1 Query: 52 RSLRHTTMAGAQ-ESLVYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPI 228 R L HT + GA + V ++ ++ T I S V+ S D L + I Sbjct: 828 RDLSHTVIIGADFTNTSLRCVNFTEANLAYSVFTKILGSVLTVAFSPDGKLFATGDSGGI 887 Query: 229 QATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFV 408 + ++ G GH +V V S DG+ SGS D +RLWD+S+G + F Sbjct: 888 VRFWEAAT--GKELLTCKGHNSWVNSVGFSQDGKMLASGSDDQTVRLWDISSGQCLKTFK 945 Query: 409 GHEKDVLSVAFSIDNRQIVSASRDRTIKLWN-TLGECKYTIGGDLG 543 GH V SV FS ++ + S S D+T++LW+ + GEC Y G G Sbjct: 946 GHTSRVRSVVFSPNSLMLASGSSDQTVRLWDISSGECLYIFQGHTG 991 Score = 73.6 bits (179), Expect = 4e-13 Identities = 46/143 (32%), Positives = 73/143 (51%), Gaps = 1/143 (0%) Frame = +1 Query: 109 VMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 +++GH V ++ D S + S S D+++ +W++ SS+ F+ GH Sbjct: 1195 ILQGHTSWVNSVVFNPDGST-LASGSSDQTVRLWEIN---------SSKCLCTFQ---GH 1241 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVS 468 +V VV + DG SGS D +RLWD+S+ F GH V SVAF+ D + S Sbjct: 1242 TSWVNSVVFNPDGSMLASGSSDKTVRLWDISSSKCLHTFQGHTNWVNSVAFNPDGSMLAS 1301 Query: 469 ASRDRTIKLWN-TLGECKYTIGG 534 S D+T++LW + +C +T G Sbjct: 1302 GSGDQTVRLWEISSSKCLHTFQG 1324 Score = 73.6 bits (179), Expect = 4e-13 Identities = 44/141 (31%), Positives = 71/141 (50%), Gaps = 1/141 (0%) Frame = +1 Query: 115 RGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGH 294 +GHN V ++ D + S S D+++ +WD+++ G + GH Sbjct: 903 KGHNSWVNSVGFSQDGK-MLASGSDDQTVRLWDISS------------GQCLKTFKGHTS 949 Query: 295 FVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSAS 474 V+ VV S + SGS D +RLWD+S+G F GH V SVAF++D + + S Sbjct: 950 RVRSVVFSPNSLMLASGSSDQTVRLWDISSGECLYIFQGHTGWVYSVAFNLDGSMLATGS 1009 Query: 475 RDRTIKLWN-TLGECKYTIGG 534 D+T++LW+ + +C Y G Sbjct: 1010 GDQTVRLWDISSSQCFYIFQG 1030 Score = 72.8 bits (177), Expect = 6e-13 Identities = 47/138 (34%), Positives = 69/138 (50%), Gaps = 1/138 (0%) Frame = +1 Query: 118 GHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHF 297 GH + V ++ D + + S S D+++ +W +++ G L GH ++ Sbjct: 1366 GHTNWVGSVIFSPDGA-ILASGSGDQTVRLWSISS------------GKCLYTLQGHNNW 1412 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASR 477 V +V S DG SGS D +RLW++S+G GH V SVAFS D + S S Sbjct: 1413 VGSIVFSPDGTLLASGSDDQTVRLWNISSGECLYTLHGHINSVRSVAFSSDGLILASGSD 1472 Query: 478 DRTIKLWNT-LGECKYTI 528 D TIKLW+ GEC T+ Sbjct: 1473 DETIKLWDVKTGECIKTL 1490 Score = 60.8 bits (146), Expect = 2e-09 Identities = 40/142 (28%), Positives = 70/142 (49%), Gaps = 1/142 (0%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 ++GH V ++ D + + S D+ + +WD+++ G L G+ Sbjct: 1070 LQGHTSCVRSVVFSPDGA-MLASGGDDQIVRLWDISS------------GNCLYTLQGYT 1116 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSA 471 +V+ +V S +G +GS D +RLWD+S+ GH V +VAFS D + S Sbjct: 1117 SWVRFLVFSPNGVTLANGSSDQIVRLWDISSKKCLYTLQGHTNWVNAVAFSPDGATLASG 1176 Query: 472 SRDRTIKLWN-TLGECKYTIGG 534 S D+T++LW+ + +C Y + G Sbjct: 1177 SGDQTVRLWDISSSKCLYILQG 1198 Score = 58.9 bits (141), Expect = 9e-09 Identities = 38/126 (30%), Positives = 57/126 (45%), Gaps = 1/126 (0%) Frame = +1 Query: 160 NSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFAL 339 N + + S D+ + +WD+++ L GH ++V V S DG Sbjct: 1127 NGVTLANGSSDQIVRLWDISSK------------KCLYTLQGHTNWVNAVAFSPDGATLA 1174 Query: 340 SGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN-TLGEC 516 SGS D +RLWD+S+ GH V SV F+ D + S S D+T++LW +C Sbjct: 1175 SGSGDQTVRLWDISSSKCLYILQGHTSWVNSVVFNPDGSTLASGSSDQTVRLWEINSSKC 1234 Query: 517 KYTIGG 534 T G Sbjct: 1235 LCTFQG 1240
>YCW2_YEAST (P25382) Hypothetical WD-repeat protein YCR072C| Length = 515 Score = 76.6 bits (187), Expect = 4e-14 Identities = 40/115 (34%), Positives = 65/115 (56%) Frame = +1 Query: 157 DNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFA 336 ++ +V++S D ++ +W NP+++T+ P R+TGH V V S DG++ Sbjct: 369 NSEEMMVTASDDYTMFLW---NPLKSTK--------PIARMTGHQKLVNHVAFSPDGRYI 417 Query: 337 LSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN 501 +S S+D ++LWD G F GH V VA+S D R +VS S+D T+K+W+ Sbjct: 418 VSASFDNSIKLWDGRDGKFISTFRGHVASVYQVAWSSDCRLLVSCSKDTTLKVWD 472 Score = 63.2 bits (152), Expect = 5e-10 Identities = 40/129 (31%), Positives = 66/129 (51%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 M GH +V +A D +IVS+S D S+ +WD ++ FR GH Sbjct: 398 MTGHQKLVNHVAFSPDGR-YIVSASFDNSIKLWD---------GRDGKFISTFR---GHV 444 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSA 471 V V SSD + +S S D L++WD+ T + GH+ +V +V +S+D +++ S Sbjct: 445 ASVYQVAWSSDCRLLVSCSKDTTLKVWDVRTRKLSVDLPGHKDEVYTVDWSVDGKRVCSG 504 Query: 472 SRDRTIKLW 498 +D+ ++LW Sbjct: 505 GKDKMVRLW 513 Score = 62.0 bits (149), Expect = 1e-09 Identities = 43/153 (28%), Positives = 72/153 (47%), Gaps = 9/153 (5%) Frame = +1 Query: 103 AGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLT 282 + + GH + A S +V+ + D + +WD DT + P L Sbjct: 136 SSAIAGHGSTILCSAFAPHTSSRMVTGAGDNTARIWDC--------DTQT----PMHTLK 183 Query: 283 GHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFV-GHEKDVLSVAFSI---- 447 GH ++V V S DG+ +GS D +RLWD +G + GH K + S+++ Sbjct: 184 GHYNWVLCVSWSPDGEVIATGSMDNTIRLWDPKSGQCLGDALRGHSKWITSLSWEPIHLV 243 Query: 448 ---DNRQIVSASRDRTIKLWNTLGE-CKYTIGG 534 ++ S+S+D TIK+W+T+ C+YT+ G Sbjct: 244 KPGSKPRLASSSKDGTIKIWDTVSRVCQYTMSG 276 Score = 38.5 bits (88), Expect = 0.013 Identities = 35/144 (24%), Positives = 58/144 (40%), Gaps = 9/144 (6%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 ++GH + V ++ D I + S D ++ +WD + Q D L GH Sbjct: 182 LKGHYNWVLCVSWSPDGE-VIATGSMDNTIRLWDPKSG-QCLGDA----------LRGHS 229 Query: 292 HFVQDV-------VLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSID 450 ++ + V S S DG +++WD + V GH V V + Sbjct: 230 KWITSLSWEPIHLVKPGSKPRLASSSKDGTIKIWDTVSRVCQYTMSGHTNSVSCVKWG-G 288 Query: 451 NRQIVSASRDRTIKLW--NTLGEC 516 + S S DRT+++W N+ G C Sbjct: 289 QGLLYSGSHDRTVRVWDINSQGRC 312
>UTP13_SCHPO (Q9USN3) Probable U3 small nucleolar RNA-associated protein 13 (U3| snoRNA-associated protein 13) Length = 777 Score = 73.9 bits (180), Expect = 3e-13 Identities = 48/150 (32%), Positives = 78/150 (52%), Gaps = 5/150 (3%) Frame = +1 Query: 109 VMRGHNDVVTAIAT-PIDNS---PFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRR 276 V GH VTA+A P+D + F+ SSS+D++L ++L + + + ++ Sbjct: 405 VFTGHTASVTAVALGPLDVNGYPTFLASSSQDRTLKRFNLGSQLNKSDFSNRAVWT---- 460 Query: 277 LTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNR 456 + H V + +S DG+ S S D ++LWD STG GH + V + +F+ +R Sbjct: 461 IKAHDRDVNAIQVSKDGRIIASASQDKTIKLWDSSTGEVVGVLRGHRRGVWACSFNPFSR 520 Query: 457 QIVSASRDRTIKLWNT-LGECKYTIGGDLG 543 Q+ S S DRTI++WN +C T+ G G Sbjct: 521 QLASGSGDRTIRIWNVDTQQCVQTLEGHTG 550 Score = 52.0 bits (123), Expect = 1e-06 Identities = 37/139 (26%), Positives = 62/139 (44%), Gaps = 3/139 (2%) Frame = +1 Query: 106 GVMRGHNDVVTAIATPIDNSPF---IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRR 276 GV+RGH V A + +PF + S S D+++ +W++ Q Q Sbjct: 501 GVLRGHRRGVWACSF----NPFSRQLASGSGDRTIRIWNVDTQ-QCVQT----------- 544 Query: 277 LTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNR 456 L GH + ++ S G +S + DG +++W LS+G HE V ++A D Sbjct: 545 LEGHTGAILKLIYISQGTQVVSAAADGLVKVWSLSSGECVATLDNHEDRVWALASRFDGS 604 Query: 457 QIVSASRDRTIKLWNTLGE 513 +VS D + +W + E Sbjct: 605 LLVSGGADAVVSVWKDVTE 623 Score = 45.1 bits (105), Expect = 1e-04 Identities = 19/54 (35%), Positives = 32/54 (59%) Frame = +1 Query: 340 SGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN 501 SG+ D +RLWDL++ + F GH + + F ++S SRD+T+++WN Sbjct: 164 SGADDSRVRLWDLNSSRSMAVFEGHSSVIRGLTFEPTGSFLLSGSRDKTVQVWN 217 Score = 38.1 bits (87), Expect = 0.017 Identities = 28/87 (32%), Positives = 43/87 (49%), Gaps = 9/87 (10%) Frame = +1 Query: 268 FRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRR----FVGHEKDVLSV 435 F L GH V + S DG + +G+ D +RLW+L+ + F GH V +V Sbjct: 357 FGVLEGHTDIVLTLDSSEDGVWLATGAKDNTVRLWNLNIEDNVYKCIHVFTGHTASVTAV 416 Query: 436 AFS-IDNRQ----IVSASRDRTIKLWN 501 A +D + S+S+DRT+K +N Sbjct: 417 ALGPLDVNGYPTFLASSSQDRTLKRFN 443 Score = 37.0 bits (84), Expect = 0.037 Identities = 24/89 (26%), Positives = 42/89 (47%), Gaps = 1/89 (1%) Frame = +1 Query: 115 RGHNDVVTAIATPIDNSPFIVSSSRDKSLL-VWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 RGH V++A+ + ++++S D S + +WDL SS F GH Sbjct: 142 RGHGGVISALCFGKHQNTWVLASGADDSRVRLWDLN---------SSRSMAVFE---GHS 189 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDL 378 ++ + G F LSGS D +++W++ Sbjct: 190 SVIRGLTFEPTGSFLLSGSRDKTVQVWNI 218 Score = 36.6 bits (83), Expect = 0.049 Identities = 24/133 (18%), Positives = 58/133 (43%), Gaps = 2/133 (1%) Frame = +1 Query: 109 VMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 + + +D VTA+A D+ ++++ R + L ++++ + G + + H Sbjct: 56 IKKDEDDYVTALAITSDSKK-LIAAFRSRLLTIYEIPS------------GRRIKSMKAH 102 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQ--I 462 V + + +G +G +++WD++ T F GH + ++ F + Sbjct: 103 ETPVITMTIDPTNTLLATGGAEGLVKVWDIAGAYVTHSFRGHGGVISALCFGKHQNTWVL 162 Query: 463 VSASRDRTIKLWN 501 S + D ++LW+ Sbjct: 163 ASGADDSRVRLWD 175 Score = 32.7 bits (73), Expect = 0.70 Identities = 20/112 (17%), Positives = 51/112 (45%) Frame = +1 Query: 175 VSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSWD 354 V+ ++ +LV LT+ I T+ + E ++ +V + ++SD + ++ Sbjct: 25 VAFDSNEKILVTALTDRIIGTRSETGERLFSIKK--DEDDYVTALAITSDSKKLIAAFRS 82 Query: 355 GELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNTLG 510 L ++++ +G + HE V+++ N + + + +K+W+ G Sbjct: 83 RLLTIYEIPSGRRIKSMKAHETPVITMTIDPTNTLLATGGAEGLVKVWDIAG 134
>TUP1_CANAL (P56093) Transcriptional repressor TUP1| Length = 514 Score = 72.4 bits (176), Expect = 8e-13 Identities = 50/142 (35%), Positives = 70/142 (49%), Gaps = 7/142 (4%) Frame = +1 Query: 109 VMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 ++RGH + ++ D +VS S D+S+ +WDL Q + S E GV Sbjct: 294 ILRGHEQDIYSLDFFPDGDR-LVSGSGDRSVRIWDLRTS-QCSLTLSIEDGVT------- 344 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFV-------GHEKDVLSVAFSI 447 V +S DG+ +GS D +R+WD +TG R GHE V SVAFS Sbjct: 345 -----TVAVSPDGKLIAAGSLDRTVRVWDSTTGFLVERLDSGNENGNGHEDSVYSVAFSN 399 Query: 448 DNRQIVSASRDRTIKLWNTLGE 513 + QI S S DRT+KLW+ G+ Sbjct: 400 NGEQIASGSLDRTVKLWHLEGK 421 Score = 61.6 bits (148), Expect = 1e-09 Identities = 43/132 (32%), Positives = 67/132 (50%), Gaps = 7/132 (5%) Frame = +1 Query: 127 DVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQ-DTSSEYGVPFRRLTGHGHFVQ 303 D VT +A D I + S D+++ VWD T + D+ +E G GH V Sbjct: 341 DGVTTVAVSPDGK-LIAAGSLDRTVRVWDSTTGFLVERLDSGNENG------NGHEDSVY 393 Query: 304 DVVLSSDGQFALSGSWDGELRLWDLSTGVTTRR------FVGHEKDVLSVAFSIDNRQIV 465 V S++G+ SGS D ++LW L G + ++ ++GH+ VLSV + DN I+ Sbjct: 394 SVAFSNNGEQIASGSLDRTVKLWHLE-GKSDKKSTCEVTYIGHKDFVLSVCCTPDNEYIL 452 Query: 466 SASRDRTIKLWN 501 S S+DR + W+ Sbjct: 453 SGSKDRGVIFWD 464 Score = 59.7 bits (143), Expect = 5e-09 Identities = 37/139 (26%), Positives = 69/139 (49%), Gaps = 3/139 (2%) Frame = +1 Query: 121 HNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNP--IQATQDTSSEYGVPFRRLTGHGH 294 H+ VV + D +++ +K+ V+++T + D SS Sbjct: 201 HSSVVCCVRFSRDGK--FIATGCNKTTQVFNVTTGELVAKLIDESSNENKDDNTTASGDL 258 Query: 295 FVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSAS 474 +++ V S DG+ +G+ D +R+WDLST + GHE+D+ S+ F D ++VS S Sbjct: 259 YIRSVCFSPDGKLLATGAEDKLIRIWDLSTKRIIKILRGHEQDIYSLDFFPDGDRLVSGS 318 Query: 475 RDRTIKLWN-TLGECKYTI 528 DR++++W+ +C T+ Sbjct: 319 GDRSVRIWDLRTSQCSLTL 337 Score = 55.5 bits (132), Expect = 1e-07 Identities = 39/131 (29%), Positives = 62/131 (47%), Gaps = 4/131 (3%) Frame = +1 Query: 118 GHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHF 297 GH D V ++A +N I S S D+++ +W L + D S V + GH F Sbjct: 387 GHEDSVYSVAFS-NNGEQIASGSLDRTVKLWHL----EGKSDKKSTCEVTY---IGHKDF 438 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQ----IV 465 V V + D ++ LSGS D + WD ++G GH V+SVA S++++ Sbjct: 439 VLSVCCTPDNEYILSGSKDRGVIFWDQASGNPLLMLQGHRNSVISVAVSLNSKGTEGIFA 498 Query: 466 SASRDRTIKLW 498 + S D ++W Sbjct: 499 TGSGDCKARIW 509
>POP2_SCHPO (O14170) WD-repeat protein pop2 (Proteolysis factor sud1)| Length = 703 Score = 71.6 bits (174), Expect = 1e-12 Identities = 52/166 (31%), Positives = 83/166 (50%), Gaps = 9/166 (5%) Frame = +1 Query: 64 HTTMAGAQESLVYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDL---TNPIQA 234 H ++ E LV + ++R ++V + P+IVS SRD +L VW L T+P Sbjct: 430 HISIIRCLEILVPSRLIRHGVEIVEP------DQPYIVSGSRDHTLRVWKLPKNTDPPYL 483 Query: 235 TQDTSS----EYGVPF-RRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTR 399 +T+S E F L GH V+ + S G +SGS+D +R+W +STG Sbjct: 484 PDNTNSIDRWEKNPYFVHTLIGHTDSVRTI--SGYGDILVSGSYDSSIRIWRVSTGECLY 541 Query: 400 RFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN-TLGECKYTIGG 534 GH + SV + + +S S D++I++W+ + G CKY + G Sbjct: 542 HLRGHSLRIYSVLYEPERNICISGSMDKSIRVWDLSTGTCKYVLEG 587 Score = 58.2 bits (139), Expect = 2e-08 Identities = 37/128 (28%), Positives = 57/128 (44%) Frame = +1 Query: 118 GHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHF 297 GH D V I+ D +VS S D S+ +W ++ G L GH Sbjct: 505 GHTDSVRTISGYGD---ILVSGSYDSSIRIWRVST------------GECLYHLRGHSLR 549 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASR 477 + V+ + +SGS D +R+WDLSTG GH D ++ +++S S Sbjct: 550 IYSVLYEPERNICISGSMDKSIRVWDLSTGTCKYVLEGH--DAFVTLLNVFQNRLISGSA 607 Query: 478 DRTIKLWN 501 D TI++W+ Sbjct: 608 DSTIRIWD 615 Score = 46.6 bits (109), Expect = 5e-05 Identities = 40/131 (30%), Positives = 62/131 (47%), Gaps = 1/131 (0%) Frame = +1 Query: 112 MRGHN-DVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 +RGH+ + + + P N +S S DKS+ VWDL+ G L GH Sbjct: 543 LRGHSLRIYSVLYEPERN--ICISGSMDKSIRVWDLST------------GTCKYVLEGH 588 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVS 468 FV +L+ +SGS D +R+WDL+TG + + S F D +I+S Sbjct: 589 DAFV--TLLNVFQNRLISGSADSTIRIWDLNTGKPLMVLPSNSGYISS--FVSDEHKIIS 644 Query: 469 ASRDRTIKLWN 501 + D ++KLW+ Sbjct: 645 GN-DGSVKLWD 654 Score = 38.1 bits (87), Expect = 0.017 Identities = 22/68 (32%), Positives = 37/68 (54%) Frame = +1 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASR 477 + ++L D SGS G +++ + TGV R GH++ V +V I +VS S Sbjct: 354 ITSLLLHKDRIITTSGS--GTIQIHNAITGVLEARLEGHKEGVWAV--KIHENTLVSGSI 409 Query: 478 DRTIKLWN 501 D+T+++WN Sbjct: 410 DKTVRVWN 417 Score = 37.0 bits (84), Expect = 0.037 Identities = 27/97 (27%), Positives = 44/97 (45%) Frame = +1 Query: 109 VMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 V+ GH+ VT + + ++S S D ++ +WDL G P L + Sbjct: 584 VLEGHDAFVTLLNVFQNR---LISGSADSTIRIWDLNT------------GKPLMVLPSN 628 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTR 399 ++ V SD +SG+ DG ++LWD+ TG R Sbjct: 629 SGYISSFV--SDEHKIISGN-DGSVKLWDVRTGKLLR 662 Score = 35.8 bits (81), Expect = 0.083 Identities = 27/94 (28%), Positives = 41/94 (43%), Gaps = 14/94 (14%) Frame = +1 Query: 259 GVPFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVA 438 GV RL GH V V + + +SGS D +R+W++ T F GH + + Sbjct: 381 GVLEARLEGHKEGVWAVKIHENT--LVSGSIDKTVRVWNIEKAKCTHIFRGHISIIRCLE 438 Query: 439 FSIDNR--------------QIVSASRDRTIKLW 498 + +R IVS SRD T+++W Sbjct: 439 ILVPSRLIRHGVEIVEPDQPYIVSGSRDHTLRVW 472
>TUP12_SCHPO (Q9UUG8) Transcriptional repressor tup12| Length = 586 Score = 71.2 bits (173), Expect = 2e-12 Identities = 45/143 (31%), Positives = 70/143 (48%), Gaps = 12/143 (8%) Frame = +1 Query: 109 VMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 ++ + V T + +P + FI + S DK + +W TSS G +L GH Sbjct: 413 ILHTDDGVTTVMFSP--DGQFIAAGSLDKVIRIW-----------TSS--GTLVEQLHGH 457 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDLST------------GVTTRRFVGHEKDVLS 432 V V S DG++ +SGS D ++LW+L G+ + F GH+ +LS Sbjct: 458 EESVYSVAFSPDGKYLVSGSLDNTIKLWELQCVSNVAPSMYKEGGICKQTFTGHKDFILS 517 Query: 433 VAFSIDNRQIVSASRDRTIKLWN 501 V S D + I+S S+DRTI+ W+ Sbjct: 518 VTVSPDGKWIISGSKDRTIQFWS 540 Score = 66.6 bits (161), Expect = 4e-11 Identities = 43/130 (33%), Positives = 65/130 (50%) Frame = +1 Query: 109 VMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 ++ GH + ++ D +VS S D+++ +WD+ Q + + Sbjct: 371 LLTGHEQEIYSLDFSKDGKT-LVSGSGDRTVCLWDVEAGEQ-------------KLILHT 416 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVS 468 V V+ S DGQF +GS D +R+W S+G + GHE+ V SVAFS D + +VS Sbjct: 417 DDGVTTVMFSPDGQFIAAGSLDKVIRIWT-SSGTLVEQLHGHEESVYSVAFSPDGKYLVS 475 Query: 469 ASRDRTIKLW 498 S D TIKLW Sbjct: 476 GSLDNTIKLW 485 Score = 66.2 bits (160), Expect = 6e-11 Identities = 36/130 (27%), Positives = 63/130 (48%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 + GH + V ++A D ++VS S D ++ +W+L E G+ + TGH Sbjct: 454 LHGHEESVYSVAFSPDGK-YLVSGSLDNTIKLWELQCVSNVAPSMYKEGGICKQTFTGHK 512 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSA 471 F+ V +S DG++ +SGS D ++ W + + GH V+SVA S + + Sbjct: 513 DFILSVTVSPDGKWIISGSKDRTIQFWSPDSPHSQLTLQGHNNSVISVAVSPNGHCFATG 572 Query: 472 SRDRTIKLWN 501 S D ++W+ Sbjct: 573 SGDLRARIWS 582 Score = 62.4 bits (150), Expect = 8e-10 Identities = 31/84 (36%), Positives = 50/84 (59%), Gaps = 1/84 (1%) Frame = +1 Query: 295 FVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSAS 474 +V+ V S DG++ +G D ++R+WD++ R GHE+++ S+ FS D + +VS S Sbjct: 336 YVRSVAFSPDGKYLATGVEDQQIRIWDIAQKRVYRLLTGHEQEIYSLDFSKDGKTLVSGS 395 Query: 475 RDRTIKLWNT-LGECKYTIGGDLG 543 DRT+ LW+ GE K + D G Sbjct: 396 GDRTVCLWDVEAGEQKLILHTDDG 419
>TAF5L_MOUSE (Q91WQ5) TAF5-like RNA polymerase II p300/CBP-associated| factor-associated factor 65 kDa subunit 5L (PCAF-associated factor 65 beta) (PAF65-beta) Length = 589 Score = 69.7 bits (169), Expect = 5e-12 Identities = 37/119 (31%), Positives = 61/119 (51%) Frame = +1 Query: 160 NSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFAL 339 NS ++ + S DK++ +W S++ G R TGH V + S +G++ Sbjct: 437 NSNYLATGSTDKTVRLW------------SAQQGNSVRLFTGHRGPVLSLSFSPNGKYLA 484 Query: 340 SGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNTLGEC 516 S D L+LWDL++G + GH + S+AFS D+ I SAS D ++++W+ C Sbjct: 485 SAGEDQRLKLWDLASGTLFKELRGHTDSITSLAFSPDSGLIASASMDNSVRVWDIRSTC 543 Score = 60.1 bits (144), Expect = 4e-09 Identities = 37/119 (31%), Positives = 55/119 (46%), Gaps = 3/119 (2%) Frame = +1 Query: 154 IDNSPF---IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSD 324 +D SPF S S D++ +W S + P R GH V V + Sbjct: 390 VDISPFSLYFASGSHDRTARLW------------SFDRTYPLRIYAGHLADVDCVKFHPN 437 Query: 325 GQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN 501 + +GS D +RLW G + R F GH VLS++FS + + + SA D+ +KLW+ Sbjct: 438 SNYLATGSTDKTVRLWSAQQGNSVRLFTGHRGPVLSLSFSPNGKYLASAGEDQRLKLWD 496 Score = 55.8 bits (133), Expect = 8e-08 Identities = 40/134 (29%), Positives = 60/134 (44%), Gaps = 3/134 (2%) Frame = +1 Query: 109 VMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDL---TNPIQATQDTSSEYGVPFRRL 279 ++RGH V + D+S ++S S D S+ WDL TN + Sbjct: 337 ILRGHCGPVYSTRFLADSSG-LLSCSEDMSIRYWDLGSFTNTVL---------------Y 380 Query: 280 TGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQ 459 GH + V DV +S + SGS D RLW R + GH DV V F ++ Sbjct: 381 QGHAYPVWDVDISPFSLYFASGSHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSNY 440 Query: 460 IVSASRDRTIKLWN 501 + + S D+T++LW+ Sbjct: 441 LATGSTDKTVRLWS 454 Score = 43.9 bits (102), Expect = 3e-04 Identities = 39/148 (26%), Positives = 60/148 (40%) Frame = +1 Query: 58 LRHTTMAGAQESLVYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQAT 237 L +T + L+ AG + + + + + P V +SR + L D + Sbjct: 270 LLNTAEISSDSKLLAAGFDNSCIKLWSLRSKKLKSEPHHVDTSRIR--LACDTLEEEENE 327 Query: 238 QDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHE 417 +D + G + L GH V +D LS S D +R WDL + T + GH Sbjct: 328 EDNT---GTEMKILRGHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFTNTVLYQGHA 384 Query: 418 KDVLSVAFSIDNRQIVSASRDRTIKLWN 501 V V S + S S DRT +LW+ Sbjct: 385 YPVWDVDISPFSLYFASGSHDRTARLWS 412 Score = 33.1 bits (74), Expect = 0.54 Identities = 16/35 (45%), Positives = 23/35 (65%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDL 216 +RGH D +T++A D S I S+S D S+ VWD+ Sbjct: 506 LRGHTDSITSLAFSPD-SGLIASASMDNSVRVWDI 539
>SWD3_SCHPO (O43017) Set1 complex component swd3 (Set1C component swd3)| (COMPASS component swd3) (Complex proteins associated with set1 protein swd3) Length = 380 Score = 69.7 bits (169), Expect = 5e-12 Identities = 37/123 (30%), Positives = 61/123 (49%), Gaps = 1/123 (0%) Frame = +1 Query: 163 SPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALS 342 S ++ S+S DK++ +WD E R L GH ++V + + G +S Sbjct: 108 SKYLASASDDKTIRIWDF------------EKRCSVRCLKGHTNYVSSIDFNPLGTLLVS 155 Query: 343 GSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNTL-GECK 519 GSWD +R+W+L G R H + ++SV+ S D +AS D ++W+ L G+C Sbjct: 156 GSWDETVRIWNLQDGTCLRMLPAHSEPIISVSISADGTLCATASYDGMARIWDVLSGQCL 215 Query: 520 YTI 528 T+ Sbjct: 216 KTL 218 Score = 54.3 bits (129), Expect = 2e-07 Identities = 36/129 (27%), Positives = 59/129 (45%), Gaps = 1/129 (0%) Frame = +1 Query: 118 GHNDVVTAIATPIDNSPFIVSSSRDKSLLVWD-LTNPIQATQDTSSEYGVPFRRLTGHGH 294 GH VT ++ N +I +SS D ++ +W LT ++ T L GH Sbjct: 52 GHEKSVTCVSVS-PNKRWIATSSSDGTIKIWSALTFRLECT-------------LFGHYR 97 Query: 295 FVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSAS 474 + V ++ ++ S S D +R+WD + R GH V S+ F+ +VS S Sbjct: 98 GISQVKWATGSKYLASASDDKTIRIWDFEKRCSVRCLKGHTNYVSSIDFNPLGTLLVSGS 157 Query: 475 RDRTIKLWN 501 D T+++WN Sbjct: 158 WDETVRIWN 166 Score = 49.3 bits (116), Expect = 7e-06 Identities = 34/134 (25%), Positives = 67/134 (50%), Gaps = 4/134 (2%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPF---IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLT 282 ++GH + V++I D +P +VS S D+++ +W+L + G R L Sbjct: 134 LKGHTNYVSSI----DFNPLGTLLVSGSWDETVRIWNLQD------------GTCLRMLP 177 Query: 283 GHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLS-VAFSIDNRQ 459 H + V +S+DG + S+DG R+WD+ +G + V LS + F+ + + Sbjct: 178 AHSEPIISVSISADGTLCATASYDGMARIWDVLSGQCLKTLVEPINVPLSNLQFTENRKY 237 Query: 460 IVSASRDRTIKLWN 501 ++ ++ + I+LW+ Sbjct: 238 LLVSNLNSQIRLWD 251 Score = 43.5 bits (101), Expect = 4e-04 Identities = 22/80 (27%), Positives = 41/80 (51%) Frame = +1 Query: 277 LTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNR 456 L GH V V +S + ++ + S DG +++W T GH + + V ++ ++ Sbjct: 50 LFGHEKSVTCVSVSPNKRWIATSSSDGTIKIWSALTFRLECTLFGHYRGISQVKWATGSK 109 Query: 457 QIVSASRDRTIKLWNTLGEC 516 + SAS D+TI++W+ C Sbjct: 110 YLASASDDKTIRIWDFEKRC 129
>TAF5_HUMAN (Q15542) Transcription initiation factor TFIID subunit 5| (Transcription initiation factor TFIID 100 kDa subunit) (TAF(II)100) (TAFII-100) (TAFII100) Length = 800 Score = 69.7 bits (169), Expect = 5e-12 Identities = 35/116 (30%), Positives = 58/116 (50%) Frame = +1 Query: 160 NSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFAL 339 NS ++ + S D+++ +WD+ N G R TGH + + S +G+F Sbjct: 638 NSNYVATGSADRTVRLWDVLN------------GNCVRIFTGHKGPIHSLTFSPNGRFLA 685 Query: 340 SGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNTL 507 +G+ DG + LWD+ G+ GH V S+ FS D + S S D T++LW+ + Sbjct: 686 TGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWDAI 741 Score = 55.8 bits (133), Expect = 8e-08 Identities = 42/146 (28%), Positives = 64/146 (43%), Gaps = 1/146 (0%) Frame = +1 Query: 109 VMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 ++ GH+ V + D + +++SSS D ++ +W L Q + G GH Sbjct: 538 ILYGHSGPVYGASFSPDRN-YLLSSSEDGTVRLWSL-------QTFTCLVGYK-----GH 584 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVS 468 + V D S G + +SG D RLW R F GH DV F ++ + + Sbjct: 585 NYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVAT 644 Query: 469 ASRDRTIKLWNTL-GECKYTIGGDLG 543 S DRT++LW+ L G C G G Sbjct: 645 GSADRTVRLWDVLNGNCVRIFTGHKG 670 Score = 34.3 bits (77), Expect = 0.24 Identities = 15/46 (32%), Positives = 24/46 (52%) Frame = +1 Query: 364 RLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN 501 R+ D T + GH V +FS D ++S+S D T++LW+ Sbjct: 526 RIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWS 571
>TAF5_MOUSE (Q8C092) Transcription initiation factor TFIID subunit 5| (Transcription initiation factor TFIID 100 kDa subunit) (TAF(II)100) (TAFII-100) (TAFII100) Length = 801 Score = 69.3 bits (168), Expect = 7e-12 Identities = 35/116 (30%), Positives = 58/116 (50%) Frame = +1 Query: 160 NSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFAL 339 NS ++ + S D+++ +WD+ N G R TGH + + S +G+F Sbjct: 639 NSNYVATGSADRTVRLWDVLN------------GNCVRIFTGHKGPIHSLTFSPNGRFLA 686 Query: 340 SGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNTL 507 +G+ DG + LWD+ G+ GH V S+ FS D + S S D T++LW+ + Sbjct: 687 TGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWDAV 742 Score = 54.7 bits (130), Expect = 2e-07 Identities = 41/146 (28%), Positives = 64/146 (43%), Gaps = 1/146 (0%) Frame = +1 Query: 109 VMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 ++ GH+ V + D + +++SSS D ++ +W L Q + G GH Sbjct: 539 ILYGHSGPVYGASFSPDRN-YLLSSSEDGTVRLWSL-------QTFTCLVGYK-----GH 585 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVS 468 + V D S G + +SG D RLW R F GH DV + ++ + + Sbjct: 586 NYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRYHPNSNYVAT 645 Query: 469 ASRDRTIKLWNTL-GECKYTIGGDLG 543 S DRT++LW+ L G C G G Sbjct: 646 GSADRTVRLWDVLNGNCVRIFTGHKG 671 Score = 34.3 bits (77), Expect = 0.24 Identities = 15/46 (32%), Positives = 24/46 (52%) Frame = +1 Query: 364 RLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN 501 R+ D T + GH V +FS D ++S+S D T++LW+ Sbjct: 527 RIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWS 572
>WSB2_MOUSE (O54929) WD repeat and SOCS box-containing protein 2 (WSB-2) (SOCS| box-containing WD protein SWiP-2) Length = 404 Score = 69.3 bits (168), Expect = 7e-12 Identities = 39/130 (30%), Positives = 68/130 (52%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 + GH DVV ++ S +VS+SRDK+L +WDL +++G + L+GH Sbjct: 149 LSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDL-----------NKHGKQIQVLSGHL 197 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSA 471 +V +S D S + + + LW + + R+ GH+ V+S FS D+ +V+A Sbjct: 198 QWVYCCSISPDCSMLCSAAGEKSVFLWSMRSYTLIRKLEGHQSSVVSCDFSPDSALLVTA 257 Query: 472 SRDRTIKLWN 501 S D ++ +W+ Sbjct: 258 SYDTSVIMWD 267 Score = 43.9 bits (102), Expect = 3e-04 Identities = 19/55 (34%), Positives = 36/55 (65%), Gaps = 1/55 (1%) Frame = +1 Query: 340 SGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQI-VSASRDRTIKLWN 501 +G DG++++W++ TG+ GH+ V ++F+ I VSASRD+T+++W+ Sbjct: 128 TGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWD 182
>WDS_DROME (Q9V3J8) Protein will die slowly| Length = 361 Score = 68.9 bits (167), Expect = 9e-12 Identities = 43/141 (30%), Positives = 70/141 (49%), Gaps = 2/141 (1%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRR-LTGH 288 + GH V+A+ N ++ SSS DK + +W Y F + ++GH Sbjct: 68 LAGHTKAVSAVKFS-PNGEWLASSSADKLIKIW-------------GAYDGKFEKTISGH 113 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVS 468 + DV SSD + +SGS D L++W+LSTG + + GH V F+ + IVS Sbjct: 114 KLGISDVAWSSDSRLLVSGSDDKTLKVWELSTGKSLKTLKGHSNYVFCCNFNPQSNLIVS 173 Query: 469 ASRDRTIKLWNT-LGECKYTI 528 S D ++++W+ G+C T+ Sbjct: 174 GSFDESVRIWDVRTGKCLKTL 194 Score = 68.2 bits (165), Expect = 2e-11 Identities = 44/141 (31%), Positives = 69/141 (48%), Gaps = 1/141 (0%) Frame = +1 Query: 118 GHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHF 297 GH ++ +A D S +VS S DK+L VW+L+ G + L GH ++ Sbjct: 112 GHKLGISDVAWSSD-SRLLVSGSDDKTLKVWELST------------GKSLKTLKGHSNY 158 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASR 477 V + +SGS+D +R+WD+ TG + H V +V F+ D IVS+S Sbjct: 159 VFCCNFNPQSNLIVSGSFDESVRIWDVRTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSY 218 Query: 478 DRTIKLWNTL-GECKYTIGGD 537 D ++W+T G+C T+ D Sbjct: 219 DGLCRIWDTASGQCLKTLIDD 239 Score = 61.2 bits (147), Expect = 2e-09 Identities = 42/143 (29%), Positives = 70/143 (48%), Gaps = 2/143 (1%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 ++GH++ V S IVS S D+S+ +WD+ G + L H Sbjct: 152 LKGHSNYVFCCNFN-PQSNLIVSGSFDESVRIWDVRT------------GKCLKTLPAHS 198 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLS-VAFSIDNRQIVS 468 V V + DG +S S+DG R+WD ++G + + + +S V FS + + I++ Sbjct: 199 DPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILA 258 Query: 469 ASRDRTIKLWN-TLGECKYTIGG 534 A+ D T+KLW+ + G+C T G Sbjct: 259 ATLDNTLKLWDYSKGKCLKTYTG 281 Score = 53.5 bits (127), Expect = 4e-07 Identities = 41/130 (31%), Positives = 61/130 (46%), Gaps = 3/130 (2%) Frame = +1 Query: 121 HNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFV 300 H+D V+A+ D S IVSSS D +WD + Q + + P V Sbjct: 197 HSDPVSAVHFNRDGS-LIVSSSYDGLCRIWDTASG-QCLKTLIDDDNPP----------V 244 Query: 301 QDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGH--EKDVLSVAFSI-DNRQIVSA 471 V S +G++ L+ + D L+LWD S G + + GH EK + FS+ + IVS Sbjct: 245 SFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSG 304 Query: 472 SRDRTIKLWN 501 S D + +WN Sbjct: 305 SEDNMVYIWN 314 Score = 44.7 bits (104), Expect = 2e-04 Identities = 31/120 (25%), Positives = 56/120 (46%), Gaps = 5/120 (4%) Frame = +1 Query: 160 NSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLS---SDGQ 330 N +I++++ D +L +WD + G + TGH + + + + G+ Sbjct: 252 NGKYILAATLDNTLKLWDYSK------------GKCLKTYTGHKNEKYCIFANFSVTGGK 299 Query: 331 FALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSAS--RDRTIKLWNT 504 + +SGS D + +W+L + ++ GH VL A I SA+ D+TIKLW + Sbjct: 300 WIVSGSEDNMVYIWNLQSKEVVQKLQGHTDTVLCTACHPTENIIASAALENDKTIKLWKS 359
>LIS1_RAT (P63004) Platelet-activating factor acetylhydrolase IB alpha| subunit (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1) Length = 409 Score = 68.9 bits (167), Expect = 9e-12 Identities = 51/143 (35%), Positives = 67/143 (46%), Gaps = 2/143 (1%) Frame = +1 Query: 112 MRGHNDVVT-AIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 + GH VT I P+ + +VS+S D ++ VWD E G R L GH Sbjct: 103 LSGHRSPVTRVIFHPVFS--VMVSASEDATIKVWDY------------ETGDFERTLKGH 148 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVS 468 VQD+ G+ S S D ++LWD R GH+ +V SVA + IVS Sbjct: 149 TDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVS 208 Query: 469 ASRDRTIKLWNT-LGECKYTIGG 534 ASRD+TIK+W G C T G Sbjct: 209 ASRDKTIKMWEVQTGYCVKTFTG 231 Score = 65.1 bits (157), Expect = 1e-10 Identities = 38/118 (32%), Positives = 61/118 (51%) Frame = +1 Query: 166 PFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSG 345 PF++S SRDK++ +WD++ G+ L GH ++V+ V+ S G+F LS Sbjct: 308 PFLLSGSRDKTIKMWDVST------------GMCLMTLVGHDNWVRGVLFHSGGKFILSC 355 Query: 346 SWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNTLGECK 519 + D LR+WD + HE V S+ F +V+ S D+T+K+W EC+ Sbjct: 356 ADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVW----ECR 409 Score = 61.2 bits (147), Expect = 2e-09 Identities = 40/138 (28%), Positives = 64/138 (46%), Gaps = 2/138 (1%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNS-PFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 ++GH D V I+ D+S + S S D ++ +WD R + GH Sbjct: 145 LKGHTDSVQDIS--FDHSGKLLASCSADMTIKLWDFQG------------FECIRTMHGH 190 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVS 468 H V V + +G +S S D +++W++ TG + F GH + V V + D I S Sbjct: 191 DHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIAS 250 Query: 469 ASRDRTIKLW-NTLGECK 519 S D+T+++W ECK Sbjct: 251 CSNDQTVRVWVVATKECK 268 Score = 57.4 bits (137), Expect = 3e-08 Identities = 40/148 (27%), Positives = 68/148 (45%), Gaps = 20/148 (13%) Frame = +1 Query: 118 GHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHF 297 GH + V + P + I S S D+++ VW + AT++ +E L H H Sbjct: 231 GHREWVRMVR-PNQDGTLIASCSNDQTVRVW-----VVATKECKAE-------LREHEHV 277 Query: 298 VQDVVLSSD--------------------GQFALSGSWDGELRLWDLSTGVTTRRFVGHE 417 V+ + + + G F LSGS D +++WD+STG+ VGH+ Sbjct: 278 VECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHD 337 Query: 418 KDVLSVAFSIDNRQIVSASRDRTIKLWN 501 V V F + I+S + D+T+++W+ Sbjct: 338 NWVRGVLFHSGGKFILSCADDKTLRVWD 365 Score = 55.5 bits (132), Expect = 1e-07 Identities = 43/162 (26%), Positives = 76/162 (46%), Gaps = 21/162 (12%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 M GH+ V+++A + N IVS+SRDK++ +W++ + G + TGH Sbjct: 187 MHGHDHNVSSVAI-MPNGDHIVSASRDKTIKMWEV------------QTGYCVKTFTGHR 233 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQ---- 459 +V+ V + DG S S D +R+W ++T HE V ++++ ++ Sbjct: 234 EWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSIS 293 Query: 460 ----------------IVSASRDRTIKLWN-TLGECKYTIGG 534 ++S SRD+TIK+W+ + G C T+ G Sbjct: 294 EATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVG 335
>LIS1_PANTR (Q5IS43) Platelet-activating factor acetylhydrolase IB alpha| subunit (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1) Length = 409 Score = 68.9 bits (167), Expect = 9e-12 Identities = 51/143 (35%), Positives = 67/143 (46%), Gaps = 2/143 (1%) Frame = +1 Query: 112 MRGHNDVVT-AIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 + GH VT I P+ + +VS+S D ++ VWD E G R L GH Sbjct: 103 LSGHRSPVTRVIFHPVFS--VMVSASEDATIKVWDY------------ETGDFERTLKGH 148 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVS 468 VQD+ G+ S S D ++LWD R GH+ +V SVA + IVS Sbjct: 149 TDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVS 208 Query: 469 ASRDRTIKLWNT-LGECKYTIGG 534 ASRD+TIK+W G C T G Sbjct: 209 ASRDKTIKMWEVQTGYCVKTFTG 231 Score = 62.8 bits (151), Expect = 6e-10 Identities = 37/118 (31%), Positives = 60/118 (50%) Frame = +1 Query: 166 PFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSG 345 PF++S SRDK++ +WD++ G+ L GH ++V+ V+ S G+F LS Sbjct: 308 PFLLSGSRDKTIKMWDVST------------GMCLMTLVGHDNWVRGVLFHSGGKFILSC 355 Query: 346 SWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNTLGECK 519 + D LR+WD + HE V S+ F +V+ D+T+K+W EC+ Sbjct: 356 ADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGFVDQTVKVW----ECR 409 Score = 61.2 bits (147), Expect = 2e-09 Identities = 40/138 (28%), Positives = 64/138 (46%), Gaps = 2/138 (1%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNS-PFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 ++GH D V I+ D+S + S S D ++ +WD R + GH Sbjct: 145 LKGHTDSVQDIS--FDHSGKLLASCSADMTIKLWDFQG------------FECIRTMHGH 190 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVS 468 H V V + +G +S S D +++W++ TG + F GH + V V + D I S Sbjct: 191 DHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIAS 250 Query: 469 ASRDRTIKLW-NTLGECK 519 S D+T+++W ECK Sbjct: 251 CSNDQTVRVWVVATKECK 268 Score = 57.4 bits (137), Expect = 3e-08 Identities = 40/148 (27%), Positives = 68/148 (45%), Gaps = 20/148 (13%) Frame = +1 Query: 118 GHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHF 297 GH + V + P + I S S D+++ VW + AT++ +E L H H Sbjct: 231 GHREWVRMVR-PNQDGTLIASCSNDQTVRVW-----VVATKECKAE-------LREHEHV 277 Query: 298 VQDVVLSSD--------------------GQFALSGSWDGELRLWDLSTGVTTRRFVGHE 417 V+ + + + G F LSGS D +++WD+STG+ VGH+ Sbjct: 278 VECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHD 337 Query: 418 KDVLSVAFSIDNRQIVSASRDRTIKLWN 501 V V F + I+S + D+T+++W+ Sbjct: 338 NWVRGVLFHSGGKFILSCADDKTLRVWD 365 Score = 55.5 bits (132), Expect = 1e-07 Identities = 43/162 (26%), Positives = 76/162 (46%), Gaps = 21/162 (12%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 M GH+ V+++A + N IVS+SRDK++ +W++ + G + TGH Sbjct: 187 MHGHDHNVSSVAI-MPNGDHIVSASRDKTIKMWEV------------QTGYCVKTFTGHR 233 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQ---- 459 +V+ V + DG S S D +R+W ++T HE V ++++ ++ Sbjct: 234 EWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSIS 293 Query: 460 ----------------IVSASRDRTIKLWN-TLGECKYTIGG 534 ++S SRD+TIK+W+ + G C T+ G Sbjct: 294 EATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVG 335
>LIS1_MOUSE (P63005) Platelet-activating factor acetylhydrolase IB alpha| subunit (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1) Length = 409 Score = 68.9 bits (167), Expect = 9e-12 Identities = 51/143 (35%), Positives = 67/143 (46%), Gaps = 2/143 (1%) Frame = +1 Query: 112 MRGHNDVVT-AIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 + GH VT I P+ + +VS+S D ++ VWD E G R L GH Sbjct: 103 LSGHRSPVTRVIFHPVFS--VMVSASEDATIKVWDY------------ETGDFERTLKGH 148 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVS 468 VQD+ G+ S S D ++LWD R GH+ +V SVA + IVS Sbjct: 149 TDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVS 208 Query: 469 ASRDRTIKLWNT-LGECKYTIGG 534 ASRD+TIK+W G C T G Sbjct: 209 ASRDKTIKMWEVQTGYCVKTFTG 231 Score = 65.1 bits (157), Expect = 1e-10 Identities = 38/118 (32%), Positives = 61/118 (51%) Frame = +1 Query: 166 PFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSG 345 PF++S SRDK++ +WD++ G+ L GH ++V+ V+ S G+F LS Sbjct: 308 PFLLSGSRDKTIKMWDVST------------GMCLMTLVGHDNWVRGVLFHSGGKFILSC 355 Query: 346 SWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNTLGECK 519 + D LR+WD + HE V S+ F +V+ S D+T+K+W EC+ Sbjct: 356 ADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVW----ECR 409 Score = 61.2 bits (147), Expect = 2e-09 Identities = 40/138 (28%), Positives = 64/138 (46%), Gaps = 2/138 (1%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNS-PFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 ++GH D V I+ D+S + S S D ++ +WD R + GH Sbjct: 145 LKGHTDSVQDIS--FDHSGKLLASCSADMTIKLWDFQG------------FECIRTMHGH 190 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVS 468 H V V + +G +S S D +++W++ TG + F GH + V V + D I S Sbjct: 191 DHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIAS 250 Query: 469 ASRDRTIKLW-NTLGECK 519 S D+T+++W ECK Sbjct: 251 CSNDQTVRVWVVATKECK 268 Score = 57.4 bits (137), Expect = 3e-08 Identities = 40/148 (27%), Positives = 68/148 (45%), Gaps = 20/148 (13%) Frame = +1 Query: 118 GHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHF 297 GH + V + P + I S S D+++ VW + AT++ +E L H H Sbjct: 231 GHREWVRMVR-PNQDGTLIASCSNDQTVRVW-----VVATKECKAE-------LREHEHV 277 Query: 298 VQDVVLSSD--------------------GQFALSGSWDGELRLWDLSTGVTTRRFVGHE 417 V+ + + + G F LSGS D +++WD+STG+ VGH+ Sbjct: 278 VECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHD 337 Query: 418 KDVLSVAFSIDNRQIVSASRDRTIKLWN 501 V V F + I+S + D+T+++W+ Sbjct: 338 NWVRGVLFHSGGKFILSCADDKTLRVWD 365 Score = 55.5 bits (132), Expect = 1e-07 Identities = 43/162 (26%), Positives = 76/162 (46%), Gaps = 21/162 (12%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 M GH+ V+++A + N IVS+SRDK++ +W++ + G + TGH Sbjct: 187 MHGHDHNVSSVAI-MPNGDHIVSASRDKTIKMWEV------------QTGYCVKTFTGHR 233 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQ---- 459 +V+ V + DG S S D +R+W ++T HE V ++++ ++ Sbjct: 234 EWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSIS 293 Query: 460 ----------------IVSASRDRTIKLWN-TLGECKYTIGG 534 ++S SRD+TIK+W+ + G C T+ G Sbjct: 294 EATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVG 335
>LIS1_HUMAN (P43034) Platelet-activating factor acetylhydrolase IB alpha| subunit (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1) Length = 409 Score = 68.9 bits (167), Expect = 9e-12 Identities = 51/143 (35%), Positives = 67/143 (46%), Gaps = 2/143 (1%) Frame = +1 Query: 112 MRGHNDVVT-AIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 + GH VT I P+ + +VS+S D ++ VWD E G R L GH Sbjct: 103 LSGHRSPVTRVIFHPVFS--VMVSASEDATIKVWDY------------ETGDFERTLKGH 148 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVS 468 VQD+ G+ S S D ++LWD R GH+ +V SVA + IVS Sbjct: 149 TDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVS 208 Query: 469 ASRDRTIKLWNT-LGECKYTIGG 534 ASRD+TIK+W G C T G Sbjct: 209 ASRDKTIKMWEVQTGYCVKTFTG 231 Score = 65.1 bits (157), Expect = 1e-10 Identities = 38/118 (32%), Positives = 61/118 (51%) Frame = +1 Query: 166 PFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSG 345 PF++S SRDK++ +WD++ G+ L GH ++V+ V+ S G+F LS Sbjct: 308 PFLLSGSRDKTIKMWDVST------------GMCLMTLVGHDNWVRGVLFHSGGKFILSC 355 Query: 346 SWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNTLGECK 519 + D LR+WD + HE V S+ F +V+ S D+T+K+W EC+ Sbjct: 356 ADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVW----ECR 409 Score = 61.2 bits (147), Expect = 2e-09 Identities = 40/138 (28%), Positives = 64/138 (46%), Gaps = 2/138 (1%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNS-PFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 ++GH D V I+ D+S + S S D ++ +WD R + GH Sbjct: 145 LKGHTDSVQDIS--FDHSGKLLASCSADMTIKLWDFQG------------FECIRTMHGH 190 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVS 468 H V V + +G +S S D +++W++ TG + F GH + V V + D I S Sbjct: 191 DHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIAS 250 Query: 469 ASRDRTIKLW-NTLGECK 519 S D+T+++W ECK Sbjct: 251 CSNDQTVRVWVVATKECK 268 Score = 57.4 bits (137), Expect = 3e-08 Identities = 40/148 (27%), Positives = 68/148 (45%), Gaps = 20/148 (13%) Frame = +1 Query: 118 GHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHF 297 GH + V + P + I S S D+++ VW + AT++ +E L H H Sbjct: 231 GHREWVRMVR-PNQDGTLIASCSNDQTVRVW-----VVATKECKAE-------LREHEHV 277 Query: 298 VQDVVLSSD--------------------GQFALSGSWDGELRLWDLSTGVTTRRFVGHE 417 V+ + + + G F LSGS D +++WD+STG+ VGH+ Sbjct: 278 VECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHD 337 Query: 418 KDVLSVAFSIDNRQIVSASRDRTIKLWN 501 V V F + I+S + D+T+++W+ Sbjct: 338 NWVRGVLFHSGGKFILSCADDKTLRVWD 365 Score = 55.5 bits (132), Expect = 1e-07 Identities = 43/162 (26%), Positives = 76/162 (46%), Gaps = 21/162 (12%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 M GH+ V+++A + N IVS+SRDK++ +W++ + G + TGH Sbjct: 187 MHGHDHNVSSVAI-MPNGDHIVSASRDKTIKMWEV------------QTGYCVKTFTGHR 233 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQ---- 459 +V+ V + DG S S D +R+W ++T HE V ++++ ++ Sbjct: 234 EWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSIS 293 Query: 460 ----------------IVSASRDRTIKLWN-TLGECKYTIGG 534 ++S SRD+TIK+W+ + G C T+ G Sbjct: 294 EATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVG 335
>WSB2_HUMAN (Q9NYS7) WD repeat and SOCS box-containing protein 2 (WSB-2) (CS| box-containing WD protein) Length = 404 Score = 68.9 bits (167), Expect = 9e-12 Identities = 39/130 (30%), Positives = 67/130 (51%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 + GH DVV ++ S +VS+SRDK+L +WDL +++G + L+GH Sbjct: 149 LSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDL-----------NKHGKQIQVLSGHL 197 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSA 471 +V +S D S + + + LW + + R+ GH+ V+S FS D+ +V+A Sbjct: 198 QWVYCCSISPDCSMLCSAAGEKSVFLWSMRSYTLIRKLEGHQSSVVSCDFSPDSALLVTA 257 Query: 472 SRDRTIKLWN 501 S D + +W+ Sbjct: 258 SYDTNVIMWD 267 Score = 43.9 bits (102), Expect = 3e-04 Identities = 19/55 (34%), Positives = 36/55 (65%), Gaps = 1/55 (1%) Frame = +1 Query: 340 SGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQI-VSASRDRTIKLWN 501 +G DG++++W++ TG+ GH+ V ++F+ I VSASRD+T+++W+ Sbjct: 128 TGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWD 182
>POP1_SCHPO (P87060) WD-repeat protein pop1| Length = 775 Score = 68.9 bits (167), Expect = 9e-12 Identities = 50/138 (36%), Positives = 67/138 (48%), Gaps = 15/138 (10%) Frame = +1 Query: 166 PFIVSSSRDKSLLVWDLT------------NPIQATQDTSSEYGVPF--RRLTGHGHFVQ 303 P+I+SSSRD ++ +W L NP Q TS+ PF R L GH V+ Sbjct: 523 PYIISSSRDCTIRLWSLPCLDDPPFVNVNENPDQNNDFTSATTN-PFYIRTLRGHTDSVR 581 Query: 304 DVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDR 483 +V D +S S+DG LR+W STGV GH V SV + +Q +SA D Sbjct: 582 EVACLGD--LIVSASYDGTLRVWKASTGVCLHVLRGHVGRVYSVTINPSRQQCISAGTDA 639 Query: 484 TIKLWN-TLGECKYTIGG 534 I++WN GE T+ G Sbjct: 640 KIRIWNLESGELLQTLHG 657 Score = 58.2 bits (139), Expect = 2e-08 Identities = 43/149 (28%), Positives = 66/149 (44%), Gaps = 1/149 (0%) Frame = +1 Query: 100 YAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRL 279 Y +RGH D V +A D IVS+S D +L VW + GV L Sbjct: 569 YIRTLRGHTDSVREVACLGD---LIVSASYDGTLRVWKAST------------GVCLHVL 613 Query: 280 TGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQ 459 GH V V ++ Q +S D ++R+W+L +G + GH V V F+ + Sbjct: 614 RGHVGRVYSVTINPSRQQCISAGTDAKIRIWNLESGELLQTLHGHSNLVSQVTFNQNILV 673 Query: 460 IVSASRDRTIKLWN-TLGECKYTIGGDLG 543 SA D ++++W+ G C+ + LG Sbjct: 674 SASAPPDTSLRVWDLNTGSCRDILKCPLG 702 Score = 37.7 bits (86), Expect = 0.022 Identities = 36/141 (25%), Positives = 52/141 (36%), Gaps = 24/141 (17%) Frame = +1 Query: 151 PIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQ 330 PI I D ++ +P DT + GV R L H V G Sbjct: 402 PIHGVRLITKLQFDDDKIIVSTCSPRINIYDTKT--GVLIRSLEEHEGDVW--TFEYVGD 457 Query: 331 FALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQ----------------- 459 ++GS D +R+WDL TG + F GH + + N+ Sbjct: 458 TLVTGSTDRTVRVWDLRTGECKQVFYGHTSTIRCIKIVQGNQSTTDTDDVEKENRPASND 517 Query: 460 -------IVSASRDRTIKLWN 501 I+S+SRD TI+LW+ Sbjct: 518 ANSMPPYIISSSRDCTIRLWS 538
>TUP1_YEAST (P16649) Glucose repression regulatory protein TUP1 (Flocculation| suppressor protein) (Repressor AER2) Length = 713 Score = 68.6 bits (166), Expect = 1e-11 Identities = 44/138 (31%), Positives = 71/138 (51%), Gaps = 13/138 (9%) Frame = +1 Query: 127 DVVTAIATPIDNSPFIVSSSRDKSLLVWDL-TNPIQATQDTSSEYGVPFRRLTGHGHFVQ 303 D VT +A + +I + S D+++ VWD T + D+ +E G TGH V Sbjct: 527 DGVTTVAVSPGDGKYIAAGSLDRAVRVWDSETGFLVERLDSENESG------TGHKDSVY 580 Query: 304 DVVLSSDGQFALSGSWDGELRLWDL------------STGVTTRRFVGHEKDVLSVAFSI 447 VV + DGQ +SGS D ++LW+L ++G ++GH+ VLSVA + Sbjct: 581 SVVFTRDGQSVVSGSLDRSVKLWNLQNANNKSDSKTPNSGTCEVTYIGHKDFVLSVATTQ 640 Query: 448 DNRQIVSASRDRTIKLWN 501 ++ I+S S+DR + W+ Sbjct: 641 NDEYILSGSKDRGVLFWD 658 Score = 64.3 bits (155), Expect = 2e-10 Identities = 42/138 (30%), Positives = 66/138 (47%), Gaps = 7/138 (5%) Frame = +1 Query: 109 VMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 +++GH + ++ + +VS S D+++ +WDL Q + S E GV Sbjct: 480 ILQGHEQDIYSLDY-FPSGDKLVSGSGDRTVRIWDLRTG-QCSLTLSIEDGV-------- 529 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRF-------VGHEKDVLSVAFSI 447 V DG++ +GS D +R+WD TG R GH+ V SV F+ Sbjct: 530 ---TTVAVSPGDGKYIAAGSLDRAVRVWDSETGFLVERLDSENESGTGHKDSVYSVVFTR 586 Query: 448 DNRQIVSASRDRTIKLWN 501 D + +VS S DR++KLWN Sbjct: 587 DGQSVVSGSLDRSVKLWN 604 Score = 57.4 bits (137), Expect = 3e-08 Identities = 25/79 (31%), Positives = 46/79 (58%), Gaps = 1/79 (1%) Frame = +1 Query: 295 FVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSAS 474 +++ V S DG+F +G+ D +R+WD+ GHE+D+ S+ + ++VS S Sbjct: 445 YIRSVCFSPDGKFLATGAEDRLIRIWDIENRKIVMILQGHEQDIYSLDYFPSGDKLVSGS 504 Query: 475 RDRTIKLWN-TLGECKYTI 528 DRT+++W+ G+C T+ Sbjct: 505 GDRTVRIWDLRTGQCSLTL 523 Score = 55.1 bits (131), Expect = 1e-07 Identities = 33/107 (30%), Positives = 49/107 (45%) Frame = +1 Query: 118 GHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHF 297 GH D V ++ D +VS S D+S+ +W+L N + + G GH F Sbjct: 574 GHKDSVYSVVFTRDGQS-VVSGSLDRSVKLWNLQNANNKSDSKTPNSGTCEVTYIGHKDF 632 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVA 438 V V + + ++ LSGS D + WD +G GH V+SVA Sbjct: 633 VLSVATTQNDEYILSGSKDRGVLFWDKKSGNPLLMLQGHRNSVISVA 679
>WDR5_MOUSE (P61965) WD-repeat protein 5 (BMP2-induced 3-kb gene protein)| (WD-repeat protein BIG-3) Length = 334 Score = 68.6 bits (166), Expect = 1e-11 Identities = 42/141 (29%), Positives = 72/141 (51%), Gaps = 1/141 (0%) Frame = +1 Query: 118 GHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHF 297 GH ++ +A D++ +VS+S DK+L +WD+++ G + L GH ++ Sbjct: 85 GHKLGISDVAWSSDSN-LLVSASDDKTLKIWDVSS------------GKCLKTLKGHSNY 131 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASR 477 V + +SGS+D +R+WD+ TG + H V +V F+ D IVS+S Sbjct: 132 VFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSY 191 Query: 478 DRTIKLWNTL-GECKYTIGGD 537 D ++W+T G+C T+ D Sbjct: 192 DGLCRIWDTASGQCLKTLIDD 212 Score = 63.9 bits (154), Expect = 3e-10 Identities = 46/167 (27%), Positives = 75/167 (44%), Gaps = 2/167 (1%) Frame = +1 Query: 34 TPRKP*RSLRHTTMAGAQESLVYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWD 213 TP KP +L+ T + GH V+++ N ++ SSS DK + +W Sbjct: 29 TPVKPNYALKFT--------------LAGHTKAVSSVKFS-PNGEWLASSSADKLIKIW- 72 Query: 214 LTNPIQATQDTSSEYGVPFRR-LTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGV 390 Y F + ++GH + DV SSD +S S D L++WD+S+G Sbjct: 73 ------------GAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGK 120 Query: 391 TTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNT-LGECKYTI 528 + GH V F+ + IVS S D ++++W+ G+C T+ Sbjct: 121 CLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTL 167 Score = 61.2 bits (147), Expect = 2e-09 Identities = 42/143 (29%), Positives = 70/143 (48%), Gaps = 2/143 (1%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 ++GH++ V S IVS S D+S+ +WD+ G + L H Sbjct: 125 LKGHSNYVFCCNFN-PQSNLIVSGSFDESVRIWDVKT------------GKCLKTLPAHS 171 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLS-VAFSIDNRQIVS 468 V V + DG +S S+DG R+WD ++G + + + +S V FS + + I++ Sbjct: 172 DPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILA 231 Query: 469 ASRDRTIKLWN-TLGECKYTIGG 534 A+ D T+KLW+ + G+C T G Sbjct: 232 ATLDNTLKLWDYSKGKCLKTYTG 254 Score = 53.5 bits (127), Expect = 4e-07 Identities = 41/130 (31%), Positives = 61/130 (46%), Gaps = 3/130 (2%) Frame = +1 Query: 121 HNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFV 300 H+D V+A+ D S IVSSS D +WD + Q + + P V Sbjct: 170 HSDPVSAVHFNRDGS-LIVSSSYDGLCRIWDTASG-QCLKTLIDDDNPP----------V 217 Query: 301 QDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGH--EKDVLSVAFSI-DNRQIVSA 471 V S +G++ L+ + D L+LWD S G + + GH EK + FS+ + IVS Sbjct: 218 SFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSG 277 Query: 472 SRDRTIKLWN 501 S D + +WN Sbjct: 278 SEDNLVYIWN 287 Score = 45.8 bits (107), Expect = 8e-05 Identities = 32/120 (26%), Positives = 57/120 (47%), Gaps = 5/120 (4%) Frame = +1 Query: 160 NSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLS---SDGQ 330 N +I++++ D +L +WD + G + TGH + + + + G+ Sbjct: 225 NGKYILAATLDNTLKLWDYSK------------GKCLKTYTGHKNEKYCIFANFSVTGGK 272 Query: 331 FALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSAS--RDRTIKLWNT 504 + +SGS D + +W+L T ++ GH V+S A I SA+ D+TIKLW + Sbjct: 273 WIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWKS 332
>WDR5_HUMAN (P61964) WD-repeat protein 5 (BMP2-induced 3-kb gene protein)| Length = 334 Score = 68.6 bits (166), Expect = 1e-11 Identities = 42/141 (29%), Positives = 72/141 (51%), Gaps = 1/141 (0%) Frame = +1 Query: 118 GHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHF 297 GH ++ +A D++ +VS+S DK+L +WD+++ G + L GH ++ Sbjct: 85 GHKLGISDVAWSSDSN-LLVSASDDKTLKIWDVSS------------GKCLKTLKGHSNY 131 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASR 477 V + +SGS+D +R+WD+ TG + H V +V F+ D IVS+S Sbjct: 132 VFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSY 191 Query: 478 DRTIKLWNTL-GECKYTIGGD 537 D ++W+T G+C T+ D Sbjct: 192 DGLCRIWDTASGQCLKTLIDD 212 Score = 63.9 bits (154), Expect = 3e-10 Identities = 46/167 (27%), Positives = 75/167 (44%), Gaps = 2/167 (1%) Frame = +1 Query: 34 TPRKP*RSLRHTTMAGAQESLVYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWD 213 TP KP +L+ T + GH V+++ N ++ SSS DK + +W Sbjct: 29 TPVKPNYALKFT--------------LAGHTKAVSSVKFS-PNGEWLASSSADKLIKIW- 72 Query: 214 LTNPIQATQDTSSEYGVPFRR-LTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGV 390 Y F + ++GH + DV SSD +S S D L++WD+S+G Sbjct: 73 ------------GAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGK 120 Query: 391 TTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNT-LGECKYTI 528 + GH V F+ + IVS S D ++++W+ G+C T+ Sbjct: 121 CLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTL 167 Score = 61.2 bits (147), Expect = 2e-09 Identities = 42/143 (29%), Positives = 70/143 (48%), Gaps = 2/143 (1%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 ++GH++ V S IVS S D+S+ +WD+ G + L H Sbjct: 125 LKGHSNYVFCCNFN-PQSNLIVSGSFDESVRIWDVKT------------GKCLKTLPAHS 171 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLS-VAFSIDNRQIVS 468 V V + DG +S S+DG R+WD ++G + + + +S V FS + + I++ Sbjct: 172 DPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILA 231 Query: 469 ASRDRTIKLWN-TLGECKYTIGG 534 A+ D T+KLW+ + G+C T G Sbjct: 232 ATLDNTLKLWDYSKGKCLKTYTG 254 Score = 53.5 bits (127), Expect = 4e-07 Identities = 41/130 (31%), Positives = 61/130 (46%), Gaps = 3/130 (2%) Frame = +1 Query: 121 HNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFV 300 H+D V+A+ D S IVSSS D +WD + Q + + P V Sbjct: 170 HSDPVSAVHFNRDGS-LIVSSSYDGLCRIWDTASG-QCLKTLIDDDNPP----------V 217 Query: 301 QDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGH--EKDVLSVAFSI-DNRQIVSA 471 V S +G++ L+ + D L+LWD S G + + GH EK + FS+ + IVS Sbjct: 218 SFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSG 277 Query: 472 SRDRTIKLWN 501 S D + +WN Sbjct: 278 SEDNLVYIWN 287 Score = 45.8 bits (107), Expect = 8e-05 Identities = 32/120 (26%), Positives = 57/120 (47%), Gaps = 5/120 (4%) Frame = +1 Query: 160 NSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLS---SDGQ 330 N +I++++ D +L +WD + G + TGH + + + + G+ Sbjct: 225 NGKYILAATLDNTLKLWDYSK------------GKCLKTYTGHKNEKYCIFANFSVTGGK 272 Query: 331 FALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSAS--RDRTIKLWNT 504 + +SGS D + +W+L T ++ GH V+S A I SA+ D+TIKLW + Sbjct: 273 WIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWKS 332
>TUP1_KLULA (P56094) Transcriptional repressor TUP1| Length = 682 Score = 68.6 bits (166), Expect = 1e-11 Identities = 45/135 (33%), Positives = 73/135 (54%), Gaps = 9/135 (6%) Frame = +1 Query: 127 DVVTAIATPIDNSPFIVSSSRDKSLLVWDL-TNPIQATQDTSSEYGVPFRRLTGHGHFVQ 303 D VT +A FI + S D+++ VWD T + D+ +E G TGH V Sbjct: 490 DGVTTVAVSPGEGKFIAAGSLDRTVRVWDSDTGFLVERLDSENELG------TGHRDSVY 543 Query: 304 DVVLSSDGQFALSGSWDGELRLWDLSTGVTTRR--------FVGHEKDVLSVAFSIDNRQ 459 VV + DG+ +SGS D ++LW+L+ G++ ++ + GH+ VLSVA + ++ Sbjct: 544 SVVFTRDGKGVVSGSLDRSVKLWNLN-GLSGQKSHAECEVTYTGHKDFVLSVATTQNDEY 602 Query: 460 IVSASRDRTIKLWNT 504 I+S S+DR + W+T Sbjct: 603 ILSGSKDRGVLFWDT 617 Score = 66.2 bits (160), Expect = 6e-11 Identities = 50/157 (31%), Positives = 71/157 (45%), Gaps = 16/157 (10%) Frame = +1 Query: 112 MRGHN-DVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 ++GH D+ + P N +VS S D+++ +WDLT + S E GV Sbjct: 444 LKGHEQDIYSLDYFPSGNK--LVSGSGDRTVRIWDLTTGT-CSLTLSIEDGV-------- 492 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRF-------VGHEKDVLSVAFSI 447 V +G+F +GS D +R+WD TG R GH V SV F+ Sbjct: 493 ---TTVAVSPGEGKFIAAGSLDRTVRVWDSDTGFLVERLDSENELGTGHRDSVYSVVFTR 549 Query: 448 DNRQIVSASRDRTIKLWNTLG--------ECKYTIGG 534 D + +VS S DR++KLWN G EC+ T G Sbjct: 550 DGKGVVSGSLDRSVKLWNLNGLSGQKSHAECEVTYTG 586 Score = 62.8 bits (151), Expect = 6e-10 Identities = 28/79 (35%), Positives = 47/79 (59%), Gaps = 1/79 (1%) Frame = +1 Query: 295 FVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSAS 474 +++ V S DG+F +G+ D +R+WDL T GHE+D+ S+ + ++VS S Sbjct: 408 YIRSVCFSPDGKFLATGAEDKLIRIWDLETKKIVMTLKGHEQDIYSLDYFPSGNKLVSGS 467 Query: 475 RDRTIKLWN-TLGECKYTI 528 DRT+++W+ T G C T+ Sbjct: 468 GDRTVRIWDLTTGTCSLTL 486 Score = 51.6 bits (122), Expect = 1e-06 Identities = 34/106 (32%), Positives = 52/106 (49%) Frame = +1 Query: 118 GHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHF 297 GH D V ++ D +VS S D+S+ +W+L + Q + +E V + TGH F Sbjct: 537 GHRDSVYSVVFTRDGKG-VVSGSLDRSVKLWNLNG--LSGQKSHAECEVTY---TGHKDF 590 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSV 435 V V + + ++ LSGS D + WD +G GH V+SV Sbjct: 591 VLSVATTQNDEYILSGSKDRGVLFWDTKSGNPLLMLQGHRNSVISV 636
>NLE1_BOVIN (Q58D20) Notchless homolog 1| Length = 485 Score = 68.2 bits (165), Expect = 2e-11 Identities = 38/110 (34%), Positives = 56/110 (50%) Frame = +1 Query: 172 IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSW 351 +VS S D +L +W + +E P R+TGH + VV S D + S S+ Sbjct: 344 LVSGSDDFTLFLW-----------SPAEDKKPLARMTGHQALINQVVFSPDSRVIASASF 392 Query: 352 DGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN 501 D ++LWD TG GH V +A+S D+R +VS S D T+K+W+ Sbjct: 393 DKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWD 442 Score = 64.7 bits (156), Expect = 2e-10 Identities = 41/148 (27%), Positives = 74/148 (50%), Gaps = 7/148 (4%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 + GH++ V ++A ++ S S D ++ WDL+ P GH Sbjct: 110 LEGHSEAVISVAFS-PTGKYLASGSGDTTVRFWDLSTE------------TPHFTCQGHR 156 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTT-RRFVGHEKDVLSVAF-----SIDN 453 H+V + S DG+ SG +G++ LWD STG R GH K + ++++ + + Sbjct: 157 HWVLSISWSPDGKKLASGCKNGQILLWDPSTGKQVGRALTGHSKWITALSWEPLHANPEC 216 Query: 454 RQIVSASRDRTIKLWN-TLGECKYTIGG 534 R + S+S+D ++++W+ T G C+ T+ G Sbjct: 217 RYVASSSKDGSVRVWDTTAGRCERTLTG 244 Score = 62.0 bits (149), Expect = 1e-09 Identities = 36/129 (27%), Positives = 61/129 (47%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 M GH ++ + D S I S+S DKS+ +WD G L GH Sbjct: 368 MTGHQALINQVVFSPD-SRVIASASFDKSIKLWD------------GRTGKYLASLRGHV 414 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSA 471 V + S+D + +SGS D L++WD+ + GH +V +V +S D +++ S Sbjct: 415 AAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLSTDLPGHADEVYAVDWSPDGQRVASG 474 Query: 472 SRDRTIKLW 498 +D+ +++W Sbjct: 475 GKDKCLRIW 483 Score = 55.1 bits (131), Expect = 1e-07 Identities = 38/133 (28%), Positives = 64/133 (48%), Gaps = 5/133 (3%) Frame = +1 Query: 115 RGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGH 294 +GH V +I+ D + S ++ +L+WD T + G R LTGH Sbjct: 153 QGHRHWVLSISWSPDGKK-LASGCKNGQILLWD--------PSTGKQVG---RALTGHSK 200 Query: 295 FV-----QDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQ 459 ++ + + + + ++ S S DG +R+WD + G R GH + V + + D Sbjct: 201 WITALSWEPLHANPECRYVASSSKDGSVRVWDTTAGRCERTLTGHAQSVTCLRWGGDG-L 259 Query: 460 IVSASRDRTIKLW 498 + SAS+DRTIK+W Sbjct: 260 LYSASQDRTIKVW 272 Score = 52.0 bits (123), Expect = 1e-06 Identities = 58/206 (28%), Positives = 82/206 (39%), Gaps = 76/206 (36%) Frame = +1 Query: 112 MRGHNDVVTAIA-TPIDNSP---FIVSSSRDKSLLVWD---------LTNPIQ------- 231 + GH+ +TA++ P+ +P ++ SSS+D S+ VWD LT Q Sbjct: 195 LTGHSKWITALSWEPLHANPECRYVASSSKDGSVRVWDTTAGRCERTLTGHAQSVTCLRW 254 Query: 232 --------ATQDTSSEY-----GVPFRRLTGHGHFVQDVVLSSD-----GQF-------- 333 A+QD + + GV R L GHGH+V + LS+D G F Sbjct: 255 GGDGLLYSASQDRTIKVWRAHDGVLCRTLQGHGHWVNTMALSTDYALRTGAFEPAEASVN 314 Query: 334 -----------------------------ALSGSWDGELRLWD-LSTGVTTRRFVGHEKD 423 +SGS D L LW R GH+ Sbjct: 315 AQDLRGSLQELKERALSRYNLVRGQGPERLVSGSDDFTLFLWSPAEDKKPLARMTGHQAL 374 Query: 424 VLSVAFSIDNRQIVSASRDRTIKLWN 501 + V FS D+R I SAS D++IKLW+ Sbjct: 375 INQVVFSPDSRVIASASFDKSIKLWD 400 Score = 33.1 bits (74), Expect = 0.54 Identities = 14/36 (38%), Positives = 21/36 (58%) Frame = +1 Query: 394 TRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN 501 T GH + V+SVAFS + + S S D T++ W+ Sbjct: 107 TSSLEGHSEAVISVAFSPTGKYLASGSGDTTVRFWD 142
>LIS1_MACFA (Q8HXX0) Platelet-activating factor acetylhydrolase IB alpha| subunit (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1) Length = 409 Score = 68.2 bits (165), Expect = 2e-11 Identities = 50/143 (34%), Positives = 67/143 (46%), Gaps = 2/143 (1%) Frame = +1 Query: 112 MRGHNDVVT-AIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 + GH VT I P+ + +VS+S D ++ VWD E G R L GH Sbjct: 103 LSGHRSPVTRVIFHPVFS--VMVSASEDATIKVWDY------------ETGDFERTLKGH 148 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVS 468 VQD+ G+ S S D ++LWD R GH+ +V SVA + +VS Sbjct: 149 TDSVQDISFDHSGKLLTSCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHLVS 208 Query: 469 ASRDRTIKLWNT-LGECKYTIGG 534 ASRD+TIK+W G C T G Sbjct: 209 ASRDKTIKMWEVQTGYCVKTFTG 231 Score = 65.1 bits (157), Expect = 1e-10 Identities = 38/118 (32%), Positives = 61/118 (51%) Frame = +1 Query: 166 PFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSG 345 PF++S SRDK++ +WD++ G+ L GH ++V+ V+ S G+F LS Sbjct: 308 PFLLSGSRDKTIKMWDVST------------GMCLMTLVGHDNWVRGVLFHSGGKFILSC 355 Query: 346 SWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNTLGECK 519 + D LR+WD + HE V S+ F +V+ S D+T+K+W EC+ Sbjct: 356 ADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVW----ECR 409 Score = 61.2 bits (147), Expect = 2e-09 Identities = 40/138 (28%), Positives = 64/138 (46%), Gaps = 2/138 (1%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNS-PFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 ++GH D V I+ D+S + S S D ++ +WD R + GH Sbjct: 145 LKGHTDSVQDIS--FDHSGKLLTSCSADMTIKLWDFQG------------FECIRTMHGH 190 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVS 468 H V V + +G +S S D +++W++ TG + F GH + V V + D I S Sbjct: 191 DHNVSSVAIMPNGDHLVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIAS 250 Query: 469 ASRDRTIKLW-NTLGECK 519 S D+T+++W ECK Sbjct: 251 CSNDQTVRVWVVATKECK 268 Score = 57.4 bits (137), Expect = 3e-08 Identities = 40/148 (27%), Positives = 68/148 (45%), Gaps = 20/148 (13%) Frame = +1 Query: 118 GHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHF 297 GH + V + P + I S S D+++ VW + AT++ +E L H H Sbjct: 231 GHREWVRMVR-PNQDGTLIASCSNDQTVRVW-----VVATKECKAE-------LREHEHV 277 Query: 298 VQDVVLSSD--------------------GQFALSGSWDGELRLWDLSTGVTTRRFVGHE 417 V+ + + + G F LSGS D +++WD+STG+ VGH+ Sbjct: 278 VECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHD 337 Query: 418 KDVLSVAFSIDNRQIVSASRDRTIKLWN 501 V V F + I+S + D+T+++W+ Sbjct: 338 NWVRGVLFHSGGKFILSCADDKTLRVWD 365 Score = 54.7 bits (130), Expect = 2e-07 Identities = 42/162 (25%), Positives = 76/162 (46%), Gaps = 21/162 (12%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 M GH+ V+++A + N +VS+SRDK++ +W++ + G + TGH Sbjct: 187 MHGHDHNVSSVAI-MPNGDHLVSASRDKTIKMWEV------------QTGYCVKTFTGHR 233 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQ---- 459 +V+ V + DG S S D +R+W ++T HE V ++++ ++ Sbjct: 234 EWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSIS 293 Query: 460 ----------------IVSASRDRTIKLWN-TLGECKYTIGG 534 ++S SRD+TIK+W+ + G C T+ G Sbjct: 294 EATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVG 335
>LIS1_CAEEL (Q9NDC9) Lissencephaly-1 homolog (Pronuclear migration abnormal| protein 1) Length = 404 Score = 68.2 bits (165), Expect = 2e-11 Identities = 42/130 (32%), Positives = 56/130 (43%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 ++GH D V IA +VS S D S+ +WD + L GH Sbjct: 144 LKGHTDAVNDIAIDAAGKQ-LVSCSSDLSIKLWDFGQTYDC-----------LKSLKGHE 191 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSA 471 H V V G F LS S D ++ WD+STG F GH V + S D SA Sbjct: 192 HTVSSVTFLPTGDFVLSASRDHTIKQWDISTGYCVYTFRGHNDWVRMIRISNDGTLFASA 251 Query: 472 SRDRTIKLWN 501 S D+T+ +W+ Sbjct: 252 SLDQTVTVWS 261 Score = 61.2 bits (147), Expect = 2e-09 Identities = 43/123 (34%), Positives = 58/123 (47%), Gaps = 2/123 (1%) Frame = +1 Query: 172 IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSW 351 + S S D ++ VWD E G R L GH V D+ + + G+ +S S Sbjct: 121 MASCSEDATIKVWDY------------ETGQLERTLKGHTDAVNDIAIDAAGKQLVSCSS 168 Query: 352 DGELRLWDL-STGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN-TLGECKYT 525 D ++LWD T + GHE V SV F ++SASRD TIK W+ + G C YT Sbjct: 169 DLSIKLWDFGQTYDCLKSLKGHEHTVSSVTFLPTGDFVLSASRDHTIKQWDISTGYCVYT 228 Query: 526 IGG 534 G Sbjct: 229 FRG 231 Score = 52.4 bits (124), Expect = 9e-07 Identities = 39/155 (25%), Positives = 67/155 (43%), Gaps = 16/155 (10%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 ++GH V+++ T + F++S+SRD ++ WD++ G GH Sbjct: 187 LKGHEHTVSSV-TFLPTGDFVLSASRDHTIKQWDIST------------GYCVYTFRGHN 233 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQ---- 459 +V+ + +S+DG S S D + +W +T HE V V ++ D Sbjct: 234 DWVRMIRISNDGTLFASASLDQTVTVWSFATKSAKLVLRDHEHAVECVEWAPDTAYTNVT 293 Query: 460 -----------IVSASRDRTIKLWN-TLGECKYTI 528 + S SRDR+IK WN G+ +T+ Sbjct: 294 GQQPEGNSTHILFSGSRDRSIKAWNINTGDVLFTL 328 Score = 48.9 bits (115), Expect = 9e-06 Identities = 26/77 (33%), Positives = 38/77 (49%) Frame = +1 Query: 271 RRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSID 450 ++LTGH + V+ S S D +++WD TG R GH V +A Sbjct: 100 QKLTGHRLPITRVIFHPLWTIMASCSEDATIKVWDYETGQLERTLKGHTDAVNDIAIDAA 159 Query: 451 NRQIVSASRDRTIKLWN 501 +Q+VS S D +IKLW+ Sbjct: 160 GKQLVSCSSDLSIKLWD 176 Score = 48.1 bits (113), Expect = 2e-05 Identities = 34/124 (27%), Positives = 58/124 (46%), Gaps = 1/124 (0%) Frame = +1 Query: 151 PIDNSPFIV-SSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDG 327 P NS I+ S SRD+S+ W++ G L H ++V+ + G Sbjct: 297 PEGNSTHILFSGSRDRSIKAWNINT------------GDVLFTLLAHENWVRGLAFHPKG 344 Query: 328 QFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNTL 507 ++ +S + D LR+W+LS + HE V +VAF + +++ S D + K+W Sbjct: 345 KYLISVADDKTLRVWELSAQRCMKAIEAHEHFVSTVAFHQTSPFVITGSVDMSCKVW--- 401 Query: 508 GECK 519 EC+ Sbjct: 402 -ECR 404
>LIS1_BOVIN (P43033) Platelet-activating factor acetylhydrolase IB alpha| subunit (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1) Length = 409 Score = 67.8 bits (164), Expect = 2e-11 Identities = 50/143 (34%), Positives = 67/143 (46%), Gaps = 2/143 (1%) Frame = +1 Query: 112 MRGHNDVVT-AIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 + GH VT I P+ + +VS+S D ++ VWD E G R L GH Sbjct: 103 LSGHRSPVTRVIFHPVFS--VMVSASEDATIKVWDY------------ETGDFERTLKGH 148 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVS 468 V+D+ G+ S S D ++LWD R GH+ +V SVA + IVS Sbjct: 149 TDSVEDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVS 208 Query: 469 ASRDRTIKLWNT-LGECKYTIGG 534 ASRD+TIK+W G C T G Sbjct: 209 ASRDKTIKMWEVQTGYCVKTFTG 231 Score = 65.1 bits (157), Expect = 1e-10 Identities = 38/118 (32%), Positives = 61/118 (51%) Frame = +1 Query: 166 PFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSG 345 PF++S SRDK++ +WD++ G+ L GH ++V+ V+ S G+F LS Sbjct: 308 PFLLSGSRDKTIKMWDVST------------GMCLMTLVGHDNWVRGVLFHSGGKFILSC 355 Query: 346 SWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNTLGECK 519 + D LR+WD + HE V S+ F +V+ S D+T+K+W EC+ Sbjct: 356 ADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVW----ECR 409 Score = 61.2 bits (147), Expect = 2e-09 Identities = 40/138 (28%), Positives = 64/138 (46%), Gaps = 2/138 (1%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNS-PFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 ++GH D V I+ D+S + S S D ++ +WD R + GH Sbjct: 145 LKGHTDSVEDIS--FDHSGKLLASCSADMTIKLWDFQG------------FECIRTMHGH 190 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVS 468 H V V + +G +S S D +++W++ TG + F GH + V V + D I S Sbjct: 191 DHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIAS 250 Query: 469 ASRDRTIKLW-NTLGECK 519 S D+T+++W ECK Sbjct: 251 CSNDQTVRVWVVATKECK 268 Score = 57.4 bits (137), Expect = 3e-08 Identities = 40/148 (27%), Positives = 68/148 (45%), Gaps = 20/148 (13%) Frame = +1 Query: 118 GHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHF 297 GH + V + P + I S S D+++ VW + AT++ +E L H H Sbjct: 231 GHREWVRMVR-PNQDGTLIASCSNDQTVRVW-----VVATKECKAE-------LREHEHV 277 Query: 298 VQDVVLSSD--------------------GQFALSGSWDGELRLWDLSTGVTTRRFVGHE 417 V+ + + + G F LSGS D +++WD+STG+ VGH+ Sbjct: 278 VECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHD 337 Query: 418 KDVLSVAFSIDNRQIVSASRDRTIKLWN 501 V V F + I+S + D+T+++W+ Sbjct: 338 NWVRGVLFHSGGKFILSCADDKTLRVWD 365 Score = 55.5 bits (132), Expect = 1e-07 Identities = 43/162 (26%), Positives = 76/162 (46%), Gaps = 21/162 (12%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 M GH+ V+++A + N IVS+SRDK++ +W++ + G + TGH Sbjct: 187 MHGHDHNVSSVAI-MPNGDHIVSASRDKTIKMWEV------------QTGYCVKTFTGHR 233 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQ---- 459 +V+ V + DG S S D +R+W ++T HE V ++++ ++ Sbjct: 234 EWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSIS 293 Query: 460 ----------------IVSASRDRTIKLWN-TLGECKYTIGG 534 ++S SRD+TIK+W+ + G C T+ G Sbjct: 294 EATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVG 335
>NLE1_PONPY (Q5RFF8) Notchless homolog 1| Length = 484 Score = 67.8 bits (164), Expect = 2e-11 Identities = 37/110 (33%), Positives = 56/110 (50%) Frame = +1 Query: 172 IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSW 351 +VS S D +L +W + +E P R+TGH + V+ S D + S S+ Sbjct: 343 LVSGSDDFTLFLW-----------SPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASF 391 Query: 352 DGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN 501 D ++LWD TG GH V +A+S D+R +VS S D T+K+W+ Sbjct: 392 DKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWD 441 Score = 62.4 bits (150), Expect = 8e-10 Identities = 40/148 (27%), Positives = 72/148 (48%), Gaps = 7/148 (4%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 + GH++ V ++A ++ S S D ++ WDL+ P GH Sbjct: 109 LEGHSEAVISVAFS-PTGKYLASGSGDTTVRFWDLSTE------------TPHFTCKGHR 155 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTT-RRFVGHEKDVLSVAF-----SIDN 453 H+V + S DG+ SG +G++ LWD STG R GH K + +++ + + Sbjct: 156 HWVLSISWSPDGKKLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPEC 215 Query: 454 RQIVSASRDRTIKLWN-TLGECKYTIGG 534 R + S+S+D ++++W+ T G C+ + G Sbjct: 216 RYVASSSKDGSVRIWDTTAGRCERILTG 243 Score = 61.2 bits (147), Expect = 2e-09 Identities = 35/129 (27%), Positives = 60/129 (46%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 M GH ++ + D S + S+S DKS+ +WD G L GH Sbjct: 367 MTGHQALINQVLFSPD-SRIVASASFDKSIKLWD------------GRTGKYLASLRGHV 413 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSA 471 V + S+D + +SGS D L++WD+ GH +V +V +S D +++ S Sbjct: 414 AAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVASG 473 Query: 472 SRDRTIKLW 498 +D+ +++W Sbjct: 474 GKDKCLRIW 482 Score = 53.1 bits (126), Expect = 5e-07 Identities = 37/133 (27%), Positives = 63/133 (47%), Gaps = 5/133 (3%) Frame = +1 Query: 115 RGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGH 294 +GH V +I+ D + S ++ +L+WD T + G R L GH Sbjct: 152 KGHRHWVLSISWSPDGKK-LASGCKNGQILLWD--------PSTGKQVG---RTLAGHSK 199 Query: 295 FV-----QDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQ 459 ++ + + + + ++ S S DG +R+WD + G R GH + V + + D Sbjct: 200 WITGLSWEPLHANPECRYVASSSKDGSVRIWDTTAGRCERILTGHTQSVTCLRWGGDG-L 258 Query: 460 IVSASRDRTIKLW 498 + SAS+DRTIK+W Sbjct: 259 LYSASQDRTIKVW 271 Score = 48.9 bits (115), Expect = 9e-06 Identities = 55/206 (26%), Positives = 81/206 (39%), Gaps = 76/206 (36%) Frame = +1 Query: 112 MRGHNDVVTAIA-TPIDNSP---FIVSSSRDKSLLVWD---------LTNPIQ------- 231 + GH+ +T ++ P+ +P ++ SSS+D S+ +WD LT Q Sbjct: 194 LAGHSKWITGLSWEPLHANPECRYVASSSKDGSVRIWDTTAGRCERILTGHTQSVTCLRW 253 Query: 232 --------ATQDTSSEY-----GVPFRRLTGHGHFVQDVVLSSD-----GQF-------- 333 A+QD + + GV R L GHGH+V + LS+D G F Sbjct: 254 GGDGLLYSASQDRTIKVWRAHDGVLCRTLQGHGHWVNTMALSTDYALRTGAFEPAEASVN 313 Query: 334 -----------------------------ALSGSWDGELRLWD-LSTGVTTRRFVGHEKD 423 +SGS D L LW R GH+ Sbjct: 314 PQDLQGSLQELKERALSRYNLMRGQGPERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQAL 373 Query: 424 VLSVAFSIDNRQIVSASRDRTIKLWN 501 + V FS D+R + SAS D++IKLW+ Sbjct: 374 INQVLFSPDSRIVASASFDKSIKLWD 399 Score = 33.1 bits (74), Expect = 0.54 Identities = 14/36 (38%), Positives = 21/36 (58%) Frame = +1 Query: 394 TRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN 501 T GH + V+SVAFS + + S S D T++ W+ Sbjct: 106 TSSLEGHSEAVISVAFSPTGKYLASGSGDTTVRFWD 141
>NLE1_MOUSE (Q8VEJ4) Notchless homolog 1| Length = 484 Score = 67.8 bits (164), Expect = 2e-11 Identities = 37/110 (33%), Positives = 56/110 (50%) Frame = +1 Query: 172 IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSW 351 +VS S D +L +W + +E P R+TGH + V+ S D + S S+ Sbjct: 343 LVSGSDDFTLFLW-----------SPAEDKKPLARMTGHQALINQVLFSPDSRIVASASF 391 Query: 352 DGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN 501 D ++LWD TG GH V +A+S D+R +VS S D T+K+W+ Sbjct: 392 DKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWD 441 Score = 63.2 bits (152), Expect = 5e-10 Identities = 40/148 (27%), Positives = 73/148 (49%), Gaps = 7/148 (4%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 + GH++ V ++A ++ S S D ++ WDL+ P GH Sbjct: 109 LEGHSEAVISVAFS-PTGKYLASGSGDTTVRFWDLSTE------------TPHFTCKGHR 155 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTT-RRFVGHEKDVLSVAF-----SIDN 453 H+V + S DG+ SG +G++ LWD STG+ R GH K + +++ + + Sbjct: 156 HWVLSISWSPDGKKLASGCKNGQILLWDPSTGLQVGRTLTGHSKWITGLSWEPLHMNPEC 215 Query: 454 RQIVSASRDRTIKLWN-TLGECKYTIGG 534 R + S+S+D ++++W+ T G C+ + G Sbjct: 216 RYVASSSKDGSVRVWDTTAGRCERILTG 243 Score = 61.2 bits (147), Expect = 2e-09 Identities = 35/129 (27%), Positives = 60/129 (46%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 M GH ++ + D S + S+S DKS+ +WD G L GH Sbjct: 367 MTGHQALINQVLFSPD-SRIVASASFDKSIKLWD------------GRTGKYLASLRGHV 413 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSA 471 V + S+D + +SGS D L++WD+ GH +V +V +S D +++ S Sbjct: 414 AAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLATDLPGHADEVYAVDWSPDGQRVASG 473 Query: 472 SRDRTIKLW 498 +D+ +++W Sbjct: 474 GKDKCLRIW 482 Score = 56.2 bits (134), Expect = 6e-08 Identities = 37/133 (27%), Positives = 65/133 (48%), Gaps = 5/133 (3%) Frame = +1 Query: 115 RGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGH 294 +GH V +I+ D + S ++ +L+WD + +Q R LTGH Sbjct: 152 KGHRHWVLSISWSPDGKK-LASGCKNGQILLWDPSTGLQVG-----------RTLTGHSK 199 Query: 295 FV-----QDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQ 459 ++ + + ++ + ++ S S DG +R+WD + G R GH + V + + D Sbjct: 200 WITGLSWEPLHMNPECRYVASSSKDGSVRVWDTTAGRCERILTGHTQSVTCLRWGGDG-L 258 Query: 460 IVSASRDRTIKLW 498 + SAS+DRTIK+W Sbjct: 259 LYSASQDRTIKVW 271 Score = 49.3 bits (116), Expect = 7e-06 Identities = 56/206 (27%), Positives = 81/206 (39%), Gaps = 76/206 (36%) Frame = +1 Query: 112 MRGHNDVVTAIA-TPIDNSP---FIVSSSRDKSLLVWD---------LTNPIQ------- 231 + GH+ +T ++ P+ +P ++ SSS+D S+ VWD LT Q Sbjct: 194 LTGHSKWITGLSWEPLHMNPECRYVASSSKDGSVRVWDTTAGRCERILTGHTQSVTCLRW 253 Query: 232 --------ATQDTSSEY-----GVPFRRLTGHGHFVQDVVLSSD-----GQF-------- 333 A+QD + + GV R L GHGH+V + LS+D G F Sbjct: 254 GGDGLLYSASQDRTIKVWRAHDGVLCRTLQGHGHWVNTMALSTDYALRTGAFEPAEATVN 313 Query: 334 -----------------------------ALSGSWDGELRLWD-LSTGVTTRRFVGHEKD 423 +SGS D L LW R GH+ Sbjct: 314 AQDLQGSLKELKERASSRYNLVRGQGPERLVSGSDDFTLFLWSPAEDKKPLARMTGHQAL 373 Query: 424 VLSVAFSIDNRQIVSASRDRTIKLWN 501 + V FS D+R + SAS D++IKLW+ Sbjct: 374 INQVLFSPDSRIVASASFDKSIKLWD 399 Score = 33.1 bits (74), Expect = 0.54 Identities = 14/36 (38%), Positives = 21/36 (58%) Frame = +1 Query: 394 TRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN 501 T GH + V+SVAFS + + S S D T++ W+ Sbjct: 106 TSSLEGHSEAVISVAFSPTGKYLASGSGDTTVRFWD 141
>NLE1_HUMAN (Q9NVX2) Notchless homolog 1| Length = 484 Score = 67.8 bits (164), Expect = 2e-11 Identities = 37/110 (33%), Positives = 56/110 (50%) Frame = +1 Query: 172 IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSW 351 +VS S D +L +W + +E P R+TGH + V+ S D + S S+ Sbjct: 343 LVSGSDDFTLFLW-----------SPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASF 391 Query: 352 DGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN 501 D ++LWD TG GH V +A+S D+R +VS S D T+K+W+ Sbjct: 392 DKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWD 441 Score = 62.4 bits (150), Expect = 8e-10 Identities = 40/148 (27%), Positives = 72/148 (48%), Gaps = 7/148 (4%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 + GH++ V ++A ++ S S D ++ WDL+ P GH Sbjct: 109 LEGHSEAVISVAFS-PTGKYLASGSGDTTVRFWDLSTE------------TPHFTCKGHR 155 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTT-RRFVGHEKDVLSVAF-----SIDN 453 H+V + S DG+ SG +G++ LWD STG R GH K + +++ + + Sbjct: 156 HWVLSISWSPDGKKLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPEC 215 Query: 454 RQIVSASRDRTIKLWN-TLGECKYTIGG 534 R + S+S+D ++++W+ T G C+ + G Sbjct: 216 RYVASSSKDGSVRIWDTTAGRCERILTG 243 Score = 61.2 bits (147), Expect = 2e-09 Identities = 35/129 (27%), Positives = 60/129 (46%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 M GH ++ + D S + S+S DKS+ +WD G L GH Sbjct: 367 MTGHQALINQVLFSPD-SRIVASASFDKSIKLWD------------GRTGKYLASLRGHV 413 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSA 471 V + S+D + +SGS D L++WD+ GH +V +V +S D +++ S Sbjct: 414 AAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVASG 473 Query: 472 SRDRTIKLW 498 +D+ +++W Sbjct: 474 GKDKCLRIW 482 Score = 53.1 bits (126), Expect = 5e-07 Identities = 37/133 (27%), Positives = 63/133 (47%), Gaps = 5/133 (3%) Frame = +1 Query: 115 RGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGH 294 +GH V +I+ D + S ++ +L+WD T + G R L GH Sbjct: 152 KGHRHWVLSISWSPDGKK-LASGCKNGQILLWD--------PSTGKQVG---RTLAGHSK 199 Query: 295 FV-----QDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQ 459 ++ + + + + ++ S S DG +R+WD + G R GH + V + + D Sbjct: 200 WITGLSWEPLHANPECRYVASSSKDGSVRIWDTTAGRCERILTGHTQSVTCLRWGGDG-L 258 Query: 460 IVSASRDRTIKLW 498 + SAS+DRTIK+W Sbjct: 259 LYSASQDRTIKVW 271 Score = 48.9 bits (115), Expect = 9e-06 Identities = 55/206 (26%), Positives = 81/206 (39%), Gaps = 76/206 (36%) Frame = +1 Query: 112 MRGHNDVVTAIA-TPIDNSP---FIVSSSRDKSLLVWD---------LTNPIQ------- 231 + GH+ +T ++ P+ +P ++ SSS+D S+ +WD LT Q Sbjct: 194 LAGHSKWITGLSWEPLHANPECRYVASSSKDGSVRIWDTTAGRCERILTGHTQSVTCLRW 253 Query: 232 --------ATQDTSSEY-----GVPFRRLTGHGHFVQDVVLSSD-----GQF-------- 333 A+QD + + GV R L GHGH+V + LS+D G F Sbjct: 254 GGDGLLYSASQDRTIKVWRAHDGVLCRTLQGHGHWVNTMALSTDYALRTGAFEPAEASVN 313 Query: 334 -----------------------------ALSGSWDGELRLWD-LSTGVTTRRFVGHEKD 423 +SGS D L LW R GH+ Sbjct: 314 PQDLQGSLQELKERALSRYNLVRGQGPERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQAL 373 Query: 424 VLSVAFSIDNRQIVSASRDRTIKLWN 501 + V FS D+R + SAS D++IKLW+ Sbjct: 374 INQVLFSPDSRIVASASFDKSIKLWD 399 Score = 33.1 bits (74), Expect = 0.54 Identities = 14/36 (38%), Positives = 21/36 (58%) Frame = +1 Query: 394 TRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN 501 T GH + V+SVAFS + + S S D T++ W+ Sbjct: 106 TSSLEGHSEAVISVAFSPTGKYLASGSGDTTVRFWD 141
>TAF5L_HUMAN (O75529) TAF5-like RNA polymerase II p300/CBP-associated| factor-associated factor 65 kDa subunit 5L (PCAF-associated factor 65 beta) (PAF65-beta) Length = 589 Score = 67.4 bits (163), Expect = 3e-11 Identities = 35/114 (30%), Positives = 60/114 (52%) Frame = +1 Query: 160 NSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFAL 339 NS ++ + S DK++ +W S++ G R TGH V + S +G++ Sbjct: 437 NSNYLATGSTDKTVRLW------------SAQQGNSVRLFTGHRGPVLSLAFSPNGKYLA 484 Query: 340 SGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN 501 S D L+LWDL++G + GH ++ S+ FS D+ I SAS D ++++W+ Sbjct: 485 SAGEDQRLKLWDLASGTLYKELRGHTDNITSLTFSPDSGLIASASMDNSVRVWD 538 Score = 59.7 bits (143), Expect = 5e-09 Identities = 37/119 (31%), Positives = 55/119 (46%), Gaps = 3/119 (2%) Frame = +1 Query: 154 IDNSPF---IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSD 324 +D SP+ S S D++ +W S + P R GH V V + Sbjct: 390 LDISPYSLYFASGSHDRTARLW------------SFDRTYPLRIYAGHLADVDCVKFHPN 437 Query: 325 GQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN 501 + +GS D +RLW G + R F GH VLS+AFS + + + SA D+ +KLW+ Sbjct: 438 SNYLATGSTDKTVRLWSAQQGNSVRLFTGHRGPVLSLAFSPNGKYLASAGEDQRLKLWD 496 Score = 54.7 bits (130), Expect = 2e-07 Identities = 39/134 (29%), Positives = 60/134 (44%), Gaps = 3/134 (2%) Frame = +1 Query: 109 VMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDL---TNPIQATQDTSSEYGVPFRRL 279 ++RGH V + D+S ++S S D S+ WDL TN + Sbjct: 337 ILRGHCGPVYSTRFLADSSG-LLSCSEDMSIRYWDLGSFTNTVL---------------Y 380 Query: 280 TGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQ 459 GH + V D+ +S + SGS D RLW R + GH DV V F ++ Sbjct: 381 QGHAYPVWDLDISPYSLYFASGSHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSNY 440 Query: 460 IVSASRDRTIKLWN 501 + + S D+T++LW+ Sbjct: 441 LATGSTDKTVRLWS 454 Score = 43.9 bits (102), Expect = 3e-04 Identities = 32/128 (25%), Positives = 52/128 (40%), Gaps = 11/128 (8%) Frame = +1 Query: 118 GHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHF 297 GH V ++A N ++ S+ D+ L +WDL + G ++ L GH Sbjct: 466 GHRGPVLSLAFS-PNGKYLASAGEDQRLKLWDLAS------------GTLYKELRGHTDN 512 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDL-----------STGVTTRRFVGHEKDVLSVAFS 444 + + S D S S D +R+WD+ S+ + G +VLSV F Sbjct: 513 ITSLTFSPDSGLIASASMDNSVRVWDIRNTYCSAPADGSSSELVGVYTGQMSNVLSVQFM 572 Query: 445 IDNRQIVS 468 N +V+ Sbjct: 573 ACNLLLVT 580 Score = 43.5 bits (101), Expect = 4e-04 Identities = 27/92 (29%), Positives = 38/92 (41%) Frame = +1 Query: 226 IQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRF 405 ++ D G + L GH V +D LS S D +R WDL + T + Sbjct: 321 LEEEDDEDDNAGTEMKILRGHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFTNTVLY 380 Query: 406 VGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN 501 GH V + S + S S DRT +LW+ Sbjct: 381 QGHAYPVWDLDISPYSLYFASGSHDRTARLWS 412
>PRP46_DEBHA (Q6BU94) Pre-mRNA-splicing factor PRP46 (Pre-mRNA-processing| protein 46) Length = 417 Score = 67.0 bits (162), Expect = 3e-11 Identities = 41/137 (29%), Positives = 65/137 (47%) Frame = +1 Query: 91 SLVYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPF 270 SL + GH V ++A P++ S S DK++ WDL + T+S G Sbjct: 153 SLNLKATITGHIMGVRSLAVS-SRYPYLFSGSEDKTVKCWDL-------ERTNSLLGCQI 204 Query: 271 RRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSID 450 R GH + + L + +G D +R+WDL + GH D+ S+A I Sbjct: 205 RNYHGHVGGIYAMALHPELDLLFTGGRDSVIRVWDLRSRTEIMVLSGHRSDITSIASQIG 264 Query: 451 NRQIVSASRDRTIKLWN 501 + QI+++S D TI+LW+ Sbjct: 265 DPQIITSSMDATIRLWD 281 Score = 38.1 bits (87), Expect = 0.017 Identities = 18/55 (32%), Positives = 30/55 (54%) Frame = +1 Query: 337 LSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN 501 ++GS D +++WDL++ GH V S+A S + S S D+T+K W+ Sbjct: 138 VTGSSDSTIKIWDLASLNLKATITGHIMGVRSLAVSSRYPYLFSGSEDKTVKCWD 192 Score = 35.4 bits (80), Expect = 0.11 Identities = 22/109 (20%), Positives = 38/109 (34%) Frame = +1 Query: 172 IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSW 351 + + RD + VWDL + + L+GH + + ++ S Sbjct: 226 LFTGGRDSVIRVWDLRSRTEIMV------------LSGHRSDITSIASQIGDPQIITSSM 273 Query: 352 DGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLW 498 D +RLWD+ T H K + +A + S +K W Sbjct: 274 DATIRLWDIRKATTQLALTHHSKSIRLMAMHPQEMTMCSGDTSGNLKEW 322
>RCO1_NEUCR (P78706) Transcriptional repressor rco-1| Length = 604 Score = 66.6 bits (161), Expect = 4e-11 Identities = 39/107 (36%), Positives = 55/107 (51%) Frame = +1 Query: 118 GHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHF 297 GH D V ++A D +VS S DK++ +W+L+ P + G + GH F Sbjct: 469 GHKDSVYSVAFSPDGRN-LVSGSLDKTIKMWELSAPRGIPSSAPPKGGRCIKTFEGHRDF 527 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVA 438 V V L+ D Q+ LSGS D ++ WD TG T GH+ V+SVA Sbjct: 528 VLSVALTPDSQWVLSGSKDRGVQFWDPRTGHTQLMLQGHKNSVISVA 574 Score = 64.7 bits (156), Expect = 2e-10 Identities = 37/127 (29%), Positives = 62/127 (48%) Frame = +1 Query: 121 HNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFV 300 H VV + +D +R + + + QD + + LTG ++ Sbjct: 296 HESVVCCVRFSMDGKYVATGCNRSAQIYDVETGEKLCILQDENID-------LTGD-LYI 347 Query: 301 QDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRD 480 + V S DG++ +G+ D +R+WD+ + F GHE+D+ S+ FS D R I S S D Sbjct: 348 RSVCFSPDGKYLATGAEDKLIRVWDIQSRTIRNTFHGHEQDIYSLDFSRDGRTIASGSGD 407 Query: 481 RTIKLWN 501 RT++LW+ Sbjct: 408 RTVRLWD 414 Score = 64.3 bits (155), Expect = 2e-10 Identities = 42/137 (30%), Positives = 65/137 (47%), Gaps = 12/137 (8%) Frame = +1 Query: 127 DVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQD 306 D VT +A D F+ + S DKS+ VWD+ + + GH V Sbjct: 428 DGVTTVAISPDKQ-FVAAGSLDKSVRVWDMRGYLAERLEGPD----------GHKDSVYS 476 Query: 307 VVLSSDGQFALSGSWDGELRLWDLST------------GVTTRRFVGHEKDVLSVAFSID 450 V S DG+ +SGS D +++W+LS G + F GH VLSVA + D Sbjct: 477 VAFSPDGRNLVSGSLDKTIKMWELSAPRGIPSSAPPKGGRCIKTFEGHRDFVLSVALTPD 536 Query: 451 NRQIVSASRDRTIKLWN 501 ++ ++S S+DR ++ W+ Sbjct: 537 SQWVLSGSKDRGVQFWD 553 Score = 63.5 bits (153), Expect = 4e-10 Identities = 47/140 (33%), Positives = 65/140 (46%), Gaps = 3/140 (2%) Frame = +1 Query: 88 ESLVYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVP 267 +S GH + ++ D I S S D+++ +WD+ Q T S E GV Sbjct: 374 QSRTIRNTFHGHEQDIYSLDFSRDGRT-IASGSGDRTVRLWDIETG-QNTSVLSIEDGVT 431 Query: 268 FRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVG---HEKDVLSVA 438 V +S D QF +GS D +R+WD+ G R G H+ V SVA Sbjct: 432 ------------TVAISPDKQFVAAGSLDKSVRVWDMR-GYLAERLEGPDGHKDSVYSVA 478 Query: 439 FSIDNRQIVSASRDRTIKLW 498 FS D R +VS S D+TIK+W Sbjct: 479 FSPDGRNLVSGSLDKTIKMW 498
>LIS1_DROME (Q7KNS3) Lissencephaly-1 homolog (Lissencephaly1) (Dlis1) (DLis-1)| Length = 411 Score = 66.6 bits (161), Expect = 4e-11 Identities = 50/144 (34%), Positives = 67/144 (46%), Gaps = 3/144 (2%) Frame = +1 Query: 112 MRGHNDVVT-AIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 + GH +T I PI +VS+S D ++ +WD E G R L GH Sbjct: 104 LTGHRASITRVIFHPI--FALMVSASEDATIRIWDF------------ETGEYERSLKGH 149 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGV-TTRRFVGHEKDVLSVAFSIDNRQIV 465 VQDV + G+ S S D ++LWD + GH+ +V SVAF ++ Sbjct: 150 TDSVQDVAFDAQGKLLASCSADLSIKLWDFQQSYECIKTMHGHDHNVSSVAFVPAGDYVL 209 Query: 466 SASRDRTIKLWN-TLGECKYTIGG 534 SASRDRTIK+W G C T G Sbjct: 210 SASRDRTIKMWEVATGYCVKTYTG 233 Score = 65.1 bits (157), Expect = 1e-10 Identities = 38/141 (26%), Positives = 63/141 (44%), Gaps = 1/141 (0%) Frame = +1 Query: 100 YAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRL 279 Y ++GH D V +A + S S D S+ +WD + + + Sbjct: 142 YERSLKGHTDSVQDVAFDAQGK-LLASCSADLSIKLWDFQQSYEC-----------IKTM 189 Query: 280 TGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQ 459 GH H V V G + LS S D +++W+++TG + + GH + V V I+ Sbjct: 190 HGHDHNVSSVAFVPAGDYVLSASRDRTIKMWEVATGYCVKTYTGHREWVRMVRVHIEGSI 249 Query: 460 IVSASRDRTIKLWNTLG-ECK 519 + S D+TI++W T +CK Sbjct: 250 FATCSNDQTIRVWLTNSKDCK 270 Score = 62.4 bits (150), Expect = 8e-10 Identities = 33/118 (27%), Positives = 60/118 (50%) Frame = +1 Query: 166 PFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSG 345 PF+ S SRDK++ +WD++ G+ L+GH ++V+ + G++ +S Sbjct: 310 PFLASGSRDKTIRIWDVS------------VGLCLLTLSGHDNWVRGLAFHPGGKYLVSA 357 Query: 346 SWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNTLGECK 519 S D +R+WDL + H+ S+ F + ++S S D+T+K+W EC+ Sbjct: 358 SDDKTIRVWDLRNKRCMKTLYAHQHFCTSIDFHKAHPYVISGSVDQTVKVW----ECR 411 Score = 56.6 bits (135), Expect = 5e-08 Identities = 43/148 (29%), Positives = 68/148 (45%), Gaps = 20/148 (13%) Frame = +1 Query: 118 GHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHF 297 GH + V + I+ S F + S D+++ VW LTN ++D E L H H Sbjct: 233 GHREWVRMVRVHIEGSIF-ATCSNDQTIRVW-LTN----SKDCKVE-------LRDHEHT 279 Query: 298 VQDVVLSSD--------------------GQFALSGSWDGELRLWDLSTGVTTRRFVGHE 417 V+ + + + G F SGS D +R+WD+S G+ GH+ Sbjct: 280 VECIAWAPEAAASAINEAAGADNKKGHHQGPFLASGSRDKTIRIWDVSVGLCLLTLSGHD 339 Query: 418 KDVLSVAFSIDNRQIVSASRDRTIKLWN 501 V +AF + +VSAS D+TI++W+ Sbjct: 340 NWVRGLAFHPGGKYLVSASDDKTIRVWD 367
>WD51A_MOUSE (Q8JZX3) WD-repeat protein 51A| Length = 405 Score = 66.2 bits (160), Expect = 6e-11 Identities = 44/143 (30%), Positives = 66/143 (46%) Frame = +1 Query: 76 AGAQESLVYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSE 255 A +QE +GH D VT + + N+ + S S D +L++W + +A Sbjct: 3 APSQEDPSLERHFKGHRDAVTCVDFSL-NTKHLASGSMDSTLMIWHMKPQSRAY------ 55 Query: 256 YGVPFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSV 435 R TGH V V S G SGS D +R+W + + F H V SV Sbjct: 56 ------RFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSV 109 Query: 436 AFSIDNRQIVSASRDRTIKLWNT 504 F D + +V+AS D+T+K+W+T Sbjct: 110 HFCSDGQSLVTASDDKTVKVWST 132 Score = 46.6 bits (109), Expect = 5e-05 Identities = 33/125 (26%), Positives = 57/125 (45%), Gaps = 1/125 (0%) Frame = +1 Query: 172 IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSW 351 IVS+S DK++ +WD T+ ++ Y HG FV V G + Sbjct: 160 IVSASDDKTVKLWDKTS-----RECIHSY-------CEHGGFVTYVDFHPSGTCIAAAGM 207 Query: 352 DGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNTL-GECKYTI 528 D +++WD T + + H V +++F +++AS D T+K+ + + G YT+ Sbjct: 208 DNTVKVWDARTHRLLQHYQLHSAAVNALSFHPSGNYLITASSDSTLKILDLMEGRLLYTL 267 Query: 529 GGDLG 543 G G Sbjct: 268 HGHQG 272 Score = 45.4 bits (106), Expect = 1e-04 Identities = 38/158 (24%), Positives = 64/158 (40%), Gaps = 30/158 (18%) Frame = +1 Query: 118 GHNDVVTAIATPIDNSPFIVSSSRDKSLLVW-------------------------DLTN 222 GH D VT + + + S SRDK++ +W D + Sbjct: 59 GHKDAVTCVNFS-PSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQS 117 Query: 223 PIQATQDTSSEYGVPFRR-----LTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTG 387 + A+ D + + R+ LT H ++V+ S DG+ +S S D ++LWD ++ Sbjct: 118 LVTASDDKTVKVWSTHRQRFLFSLTQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKTSR 177 Query: 388 VTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN 501 + H V V F I +A D T+K+W+ Sbjct: 178 ECIHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWD 215 Score = 35.4 bits (80), Expect = 0.11 Identities = 25/111 (22%), Positives = 41/111 (36%) Frame = +1 Query: 172 IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSW 351 I ++ D ++ VWD T Y + H V + G + ++ S Sbjct: 202 IAAAGMDNTVKVWDAR-----THRLLQHYQL-------HSAAVNALSFHPSGNYLITASS 249 Query: 352 DGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNT 504 D L++ DL G GH+ +VAFS S D + +W + Sbjct: 250 DSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVWKS 300
>WDR48_BRARE (Q6PFM9) WD-repeat protein 48| Length = 677 Score = 65.5 bits (158), Expect = 1e-10 Identities = 39/130 (30%), Positives = 64/130 (49%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 +R H D V A+A D + S+ D+ + +WD+ T T+S V L+G+ Sbjct: 113 LRTHKDYVKALAYAKDKE-LVASAGLDRQIFLWDVNT---LTALTASNNTVTTSSLSGNK 168 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSA 471 + + ++ G +SGS + LR+WD T + GH +V S+ + D Q +S Sbjct: 169 DSIYSLAMNQTGTVIISGSTEKVLRVWDPRTCAKLMKLKGHTDNVKSLLLNRDGTQCLSG 228 Query: 472 SRDRTIKLWN 501 S D TI+LW+ Sbjct: 229 SSDGTIRLWS 238 Score = 50.8 bits (120), Expect = 2e-06 Identities = 39/140 (27%), Positives = 60/140 (42%) Frame = +1 Query: 70 TMAGAQESLVYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTS 249 T A + V + G+ D + ++A I+S S +K L VWD + Sbjct: 150 TALTASNNTVTTSSLSGNKDSIYSLAMN-QTGTVIISGSTEKVLRVWDPRTCAK------ 202 Query: 250 SEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVL 429 +L GH V+ ++L+ DG LSGS DG +RLW L + H++ V Sbjct: 203 ------LMKLKGHTDNVKSLLLNRDGTQCLSGSSDGTIRLWSLGQQRCIATYRVHDEGVW 256 Query: 430 SVAFSIDNRQIVSASRDRTI 489 ++ + I S RDR I Sbjct: 257 ALQVNEAFTHIYSGGRDRKI 276 Score = 48.1 bits (113), Expect = 2e-05 Identities = 30/114 (26%), Positives = 53/114 (46%), Gaps = 2/114 (1%) Frame = +1 Query: 172 IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSW 351 + ++ RD + +W + Q S E+ H +V D++L +G+ +S S Sbjct: 45 LFTAGRDSIIRIWSVNQHKQDPYIASMEH---------HTDWVNDIILCCNGKTLISASS 95 Query: 352 DGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLW--NTL 507 D +++W+ G H+ V ++A++ D + SA DR I LW NTL Sbjct: 96 DTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDVNTL 149
>CDC4_YEAST (P07834) Cell division control protein 4 (F-box protein CDC4) (E3| ubiquitin ligase complex SCF subunit CDC4) Length = 779 Score = 65.1 bits (157), Expect = 1e-10 Identities = 44/154 (28%), Positives = 66/154 (42%), Gaps = 16/154 (10%) Frame = +1 Query: 109 VMRGHNDVVTAI-ATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTG 285 V +GHN V + N +IV+ SRD +L VW L + D E+ P T Sbjct: 458 VFKGHNSTVRCLDIVEYKNIKYIVTGSRDNTLHVWKLPKE-SSVPDHGEEHDYPLVFHTP 516 Query: 286 H----------GHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSV 435 GH +S G +SGS+D L +WD++ GH + S Sbjct: 517 EENPYFVGVLRGHMASVRTVSGHGNIVVSGSYDNTLIVWDVAQMKCLYILSGHTDRIYST 576 Query: 436 AFSIDNRQIVSASRDRTIKLWN-----TLGECKY 522 + + ++ +SAS D TI++W+ GEC Y Sbjct: 577 IYDHERKRCISASMDTTIRIWDLENIWNNGECSY 610 Score = 48.1 bits (113), Expect = 2e-05 Identities = 38/131 (29%), Positives = 59/131 (45%), Gaps = 2/131 (1%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 +RGH V DN ++++ + DK + V+D N Q L+GH Sbjct: 377 LRGHMTSVITCLQFEDN--YVITGADDKMIRVYDSINKKFLLQ------------LSGHD 422 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDV--LSVAFSIDNRQIV 465 V + + G +SGS D +R+WD+ G T F GH V L + + + IV Sbjct: 423 GGVWALKYAHGG-ILVSGSTDRTVRVWDIKKGCCTHVFKGHNSTVRCLDIVEYKNIKYIV 481 Query: 466 SASRDRTIKLW 498 + SRD T+ +W Sbjct: 482 TGSRDNTLHVW 492 Score = 37.0 bits (84), Expect = 0.037 Identities = 35/141 (24%), Positives = 63/141 (44%), Gaps = 7/141 (4%) Frame = +1 Query: 82 AQESLVYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQ------ATQD 243 AQ +Y ++ GH D + + + I S+S D ++ +WDL N AT Sbjct: 558 AQMKCLY--ILSGHTDRIYSTIYDHERKRCI-SASMDTTIRIWDLENIWNNGECSYATNS 614 Query: 244 TSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKD 423 S + T GH +L +F +S + DG +R WD + +R+F H + Sbjct: 615 ASPCAKILGAMYTLQGHTALVGLLRLSDKFLVSAAADGSIRGWDAND--YSRKFSYHHTN 672 Query: 424 VLSV-AFSIDNRQIVSASRDR 483 + ++ F + + +VS S ++ Sbjct: 673 LSAITTFYVSDNILVSGSENQ 693 Score = 33.5 bits (75), Expect = 0.41 Identities = 20/83 (24%), Positives = 41/83 (49%), Gaps = 1/83 (1%) Frame = +1 Query: 271 RRLTGHGHFVQDVV-LSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSI 447 +R T GH + L + + ++G+ D +R++D + GH+ V ++ ++ Sbjct: 373 QRTTLRGHMTSVITCLQFEDNYVITGADDKMIRVYDSINKKFLLQLSGHDGGVWALKYA- 431 Query: 448 DNRQIVSASRDRTIKLWNTLGEC 516 +VS S DRT+++W+ C Sbjct: 432 HGGILVSGSTDRTVRVWDIKKGC 454
>PRP46_CANAL (Q5A7Q3) Pre-mRNA-splicing factor PRP46 (Pre-mRNA-processing| protein 46) Length = 389 Score = 64.7 bits (156), Expect = 2e-10 Identities = 34/112 (30%), Positives = 57/112 (50%) Frame = +1 Query: 166 PFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSG 345 P++ S DKSL WDL + ++S+ G R GH V + L + SG Sbjct: 141 PYLFSGGEDKSLRCWDL-------ERSNSDAGCQIRSYHGHLGGVYSIGLHPELDVLFSG 193 Query: 346 SWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN 501 D +R+WD+ + V +GH D+ S+ ++ Q++++S D TI+LW+ Sbjct: 194 GKDCVVRVWDIRSRVEAMTLLGHTNDITSIETDYNDPQVITSSMDGTIRLWD 245 Score = 47.0 bits (110), Expect = 4e-05 Identities = 33/133 (24%), Positives = 56/133 (42%), Gaps = 6/133 (4%) Frame = +1 Query: 121 HNDVVTAIATPIDNSPFIVSSSRDKSLLVWDL-TNPIQATQDTSSEYGVPFRRLTGHGHF 297 H + AIA + + V+ S D ++ +WD N ++A LTGH Sbjct: 84 HQGWIRAIALDEITNKWYVTGSADSTIKIWDFENNSLKAV-------------LTGHVLG 130 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDL-----STGVTTRRFVGHEKDVLSVAFSIDNRQI 462 ++ + +S + SG D LR WDL G R + GH V S+ + + Sbjct: 131 IRSLCISKRHPYLFSGGEDKSLRCWDLERSNSDAGCQIRSYHGHLGGVYSIGLHPELDVL 190 Query: 463 VSASRDRTIKLWN 501 S +D +++W+ Sbjct: 191 FSGGKDCVVRVWD 203 Score = 42.4 bits (98), Expect = 9e-04 Identities = 26/109 (23%), Positives = 43/109 (39%) Frame = +1 Query: 172 IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSW 351 + S +D + VWD+ + ++A L GH + + + + ++ S Sbjct: 190 LFSGGKDCVVRVWDIRSRVEAMT------------LLGHTNDITSIETDYNDPQVITSSM 237 Query: 352 DGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLW 498 DG +RLWDL T H K + S+ VS + IK W Sbjct: 238 DGTIRLWDLRKSKTELLITNHSKSIRSMKSHPKEATFVSGDSNGEIKQW 286 Score = 36.6 bits (83), Expect = 0.049 Identities = 27/105 (25%), Positives = 48/105 (45%) Frame = +1 Query: 91 SLVYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPF 270 S V A + GH + +T+I T N P +++SS D ++ +WDL + + +E Sbjct: 206 SRVEAMTLLGHTNDITSIETDY-NDPQVITSSMDGTIRLWDL-------RKSKTEL---- 253 Query: 271 RRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRF 405 +T H ++ + +SG +GE++ W L G F Sbjct: 254 -LITNHSKSIRSMKSHPKEATFVSGDSNGEIKQWLLPKGELLNEF 297 Score = 32.7 bits (73), Expect = 0.70 Identities = 17/79 (21%), Positives = 37/79 (46%), Gaps = 2/79 (2%) Frame = +1 Query: 271 RRLTG-HGHFVQDVVLSS-DGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFS 444 R L G H +++ + L ++ ++GS D +++WD GH + S+ S Sbjct: 78 RTLAGAHQGWIRAIALDEITNKWYVTGSADSTIKIWDFENNSLKAVLTGHVLGIRSLCIS 137 Query: 445 IDNRQIVSASRDRTIKLWN 501 + + S D++++ W+ Sbjct: 138 KRHPYLFSGGEDKSLRCWD 156
>STRN_MOUSE (O55106) Striatin| Length = 780 Score = 64.7 bits (156), Expect = 2e-10 Identities = 43/143 (30%), Positives = 72/143 (50%), Gaps = 12/143 (8%) Frame = +1 Query: 112 MRGHNDVVTAIAT-PIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 +R H D + A+A PI+ P ++++S D +L +W+L A + TS + P H Sbjct: 459 LRSHFDGIRALAFHPIE--PVLITASEDHTLKMWNLQKTAPAKKSTSLDVE-PIYTFRAH 515 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDLST-----------GVTTRRFVGHEKDVLSV 435 V VV+SS+G+ SG DG ++ W + V +GH V + Sbjct: 516 KGPVLCVVMSSNGEQCYSGGTDGRIQSWSTTNPNVDPYDAYDPSVLRGPLLGHTDAVWGL 575 Query: 436 AFSIDNRQIVSASRDRTIKLWNT 504 A+S +++++S S D T++LWNT Sbjct: 576 AYSAAHQRLLSCSADGTLRLWNT 598 Score = 38.9 bits (89), Expect = 0.010 Identities = 22/78 (28%), Positives = 36/78 (46%), Gaps = 4/78 (5%) Frame = +1 Query: 277 LTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGH----EKDVLSVAFS 444 + H V + + +G + +SGS D +RLW+L + + F H E+ + VAF Sbjct: 702 MVAHLEAVTSLAVDPNGLYLMSGSHDCSIRLWNLESKTCIQEFTAHRKKFEESIHDVAFH 761 Query: 445 IDNRQIVSASRDRTIKLW 498 I SA D K++ Sbjct: 762 PSKCYIASAGADALAKVF 779 Score = 34.7 bits (78), Expect = 0.18 Identities = 38/181 (20%), Positives = 68/181 (37%), Gaps = 41/181 (22%) Frame = +1 Query: 82 AQESLVYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTN--PIQATQDTSSE 255 A + V G + GH D V +A + ++S S D +L +W+ T P + + + E Sbjct: 555 AYDPSVLRGPLLGHTDAVWGLAYSAAHQR-LLSCSADGTLRLWNTTEVAPALSVFNDNQE 613 Query: 256 YGVPF------------------------------RRLTGHGHF---------VQDVVLS 318 G+P R LT + + V+ Sbjct: 614 LGIPASVDLVSSDPSHMVASFSKGYTSIFNMETQQRVLTLESNVDSTSSSSCQINRVISH 673 Query: 319 SDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLW 498 +++ D ++ +D +TG V H + V S+A + ++S S D +I+LW Sbjct: 674 PTLPISITAHEDRHIKFYDNNTGKLIHSMVAHLEAVTSLAVDPNGLYLMSGSHDCSIRLW 733 Query: 499 N 501 N Sbjct: 734 N 734
>WDR31_MOUSE (Q9JHB4) WD-repeat protein 31 (Spermatid WD-repeat protein) (spWD)| Length = 367 Score = 64.3 bits (155), Expect = 2e-10 Identities = 44/131 (33%), Positives = 64/131 (48%) Frame = +1 Query: 118 GHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHF 297 GH +T IA I + S+SRDK++L+WDL Q +S P ++L+GH Sbjct: 101 GHEREITKIAC-IPKANQFFSASRDKTVLMWDL-------QGSSH----PRQQLSGHAMV 148 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASR 477 V + +S D +GS D L LWD+ TG R V + + IV S Sbjct: 149 VTGLAVSPDSSQLCTGSRDNSLLLWDVGTGQCVERASVSRNLVTHLCWVPSEPYIVQTSE 208 Query: 478 DRTIKLWNTLG 510 D+TI+LW++ G Sbjct: 209 DKTIRLWDSRG 219 Score = 48.9 bits (115), Expect = 9e-06 Identities = 37/134 (27%), Positives = 58/134 (43%), Gaps = 2/134 (1%) Frame = +1 Query: 121 HNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFV 300 H D V+ IAT NS +S +DK+ + ++ G +R TGH + Sbjct: 61 HVDTVSVIATL--NSDLCISGGKDKTAVAYNWKT------------GRMVKRFTGHEREI 106 Query: 301 QDVVLSSDGQFALSGSWDGELRLWDLSTGVTTR-RFVGHEKDVLSVAFSIDNRQIVSASR 477 + S S D + +WDL R + GH V +A S D+ Q+ + SR Sbjct: 107 TKIACIPKANQFFSASRDKTVLMWDLQGSSHPRQQLSGHAMVVTGLAVSPDSSQLCTGSR 166 Query: 478 DRTIKLWNT-LGEC 516 D ++ LW+ G+C Sbjct: 167 DNSLLLWDVGTGQC 180 Score = 36.6 bits (83), Expect = 0.049 Identities = 47/186 (25%), Positives = 72/186 (38%), Gaps = 41/186 (22%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDL-----------------------TN 222 + GH VVT +A D+S + + SRD SLL+WD+ + Sbjct: 142 LSGHAMVVTGLAVSPDSSQ-LCTGSRDNSLLLWDVGTGQCVERASVSRNLVTHLCWVPSE 200 Query: 223 P--IQATQDTS----SEYGVPFRRL-TGHGHFVQDVVLSSDGQFALS-----GSWDGELR 366 P +Q ++D + G+ + H +S DG +S G E Sbjct: 201 PYIVQTSEDKTIRLWDSRGLQMAHMFPTKQHIQTHCEVSVDGHTCISCSSGFGGEGCEAT 260 Query: 367 LWDL-STGVTTRRFVGHEKDVLSVAFSIDNR----QIVSASRDRTIKLWN-TLGECKYTI 528 LWDL T + GH + V S F + I +++ D +K+WN G C T+ Sbjct: 261 LWDLRQTRDRMCEYKGHFQTVASCVFLPKSTALMPMIATSAHDSKVKIWNQDTGACLSTL 320 Query: 529 GGDLGG 546 D G Sbjct: 321 SLDGSG 326
>YKY4_CAEEL (Q17963) Hypothetical WD-repeat protein C14B1.4| Length = 376 Score = 63.9 bits (154), Expect = 3e-10 Identities = 41/151 (27%), Positives = 72/151 (47%), Gaps = 1/151 (0%) Frame = +1 Query: 88 ESLVYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVP 267 + ++ + GH V IA D S +VS+S DK+L ++++ Sbjct: 117 DHMICERTLTGHKLGVNDIAWSSD-SRCVVSASDDKTLKIFEIVTSRMT----------- 164 Query: 268 FRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSI 447 + L GH ++V + +SGS+D +R+WD+ TG+ + H V +V+F+ Sbjct: 165 -KTLKGHNNYVFCCNFNPQSSLVVSGSFDESVRIWDVKTGMCIKTLPAHSDPVSAVSFNR 223 Query: 448 DNRQIVSASRDRTIKLWNTL-GECKYTIGGD 537 D I S S D +++W+T G+C T+ D Sbjct: 224 DGSLIASGSYDGLVRIWDTANGQCIKTLVDD 254 Score = 63.2 bits (152), Expect = 5e-10 Identities = 40/131 (30%), Positives = 65/131 (49%), Gaps = 1/131 (0%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 ++GHN+ V +S +VS S D+S+ +WD+ G+ + L H Sbjct: 167 LKGHNNYVFCCNFNPQSS-LVVSGSFDESVRIWDVKT------------GMCIKTLPAHS 213 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEK-DVLSVAFSIDNRQIVS 468 V V + DG SGS+DG +R+WD + G + V E V V FS + + I++ Sbjct: 214 DPVSAVSFNRDGSLIASGSYDGLVRIWDTANGQCIKTLVDDENPPVAFVKFSPNGKYILA 273 Query: 469 ASRDRTIKLWN 501 ++ D T+KLW+ Sbjct: 274 SNLDSTLKLWD 284 Score = 56.6 bits (135), Expect = 5e-08 Identities = 41/130 (31%), Positives = 63/130 (48%), Gaps = 3/130 (2%) Frame = +1 Query: 121 HNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFV 300 H+D V+A++ D S I S S D + +WD N Q + + P V Sbjct: 212 HSDPVSAVSFNRDGS-LIASGSYDGLVRIWDTANG-QCIKTLVDDENPP----------V 259 Query: 301 QDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHE--KDVLSVAFSI-DNRQIVSA 471 V S +G++ L+ + D L+LWD S G T +++ GHE K + FS+ + I+S Sbjct: 260 AFVKFSPNGKYILASNLDSTLKLWDFSKGKTLKQYTGHENSKYCIFANFSVTGGKWIISG 319 Query: 472 SRDRTIKLWN 501 S D I +WN Sbjct: 320 SEDCKIYIWN 329 Score = 48.5 bits (114), Expect = 1e-05 Identities = 23/74 (31%), Positives = 42/74 (56%) Frame = +1 Query: 277 LTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNR 456 L GH + S G++ + S D +++W++ + R GH+ V +A+S D+R Sbjct: 83 LEGHTKSISSAKFSPCGKYLGTSSADKTVKIWNMDHMICERTLTGHKLGVNDIAWSSDSR 142 Query: 457 QIVSASRDRTIKLW 498 +VSAS D+T+K++ Sbjct: 143 CVVSASDDKTLKIF 156 Score = 37.4 bits (85), Expect = 0.028 Identities = 23/94 (24%), Positives = 46/94 (48%), Gaps = 3/94 (3%) Frame = +1 Query: 160 NSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLS---SDGQ 330 N +I++S+ D +L +WD + G ++ TGH + + + + G+ Sbjct: 267 NGKYILASNLDSTLKLWDFSK------------GKTLKQYTGHENSKYCIFANFSVTGGK 314 Query: 331 FALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLS 432 + +SGS D ++ +W+L T + GH + VL+ Sbjct: 315 WIISGSEDCKIYIWNLQTREIVQCLEGHTQPVLA 348 Score = 32.0 bits (71), Expect = 1.2 Identities = 12/31 (38%), Positives = 20/31 (64%) Frame = +1 Query: 409 GHEKDVLSVAFSIDNRQIVSASRDRTIKLWN 501 GH K + S FS + + ++S D+T+K+WN Sbjct: 85 GHTKSISSAKFSPCGKYLGTSSADKTVKIWN 115
>Y163_SYNY3 (Q55563) Hypothetical WD-repeat protein sll0163| Length = 1693 Score = 63.5 bits (153), Expect = 4e-10 Identities = 45/145 (31%), Positives = 70/145 (48%), Gaps = 3/145 (2%) Frame = +1 Query: 109 VMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 V+RGH D V + D S +IV++S+D + VW+ T R L Sbjct: 1419 VLRGHQDAVLNVRFSPD-SQYIVTASKDGTARVWNNTG----------------RELAVL 1461 Query: 289 GHFVQDVV---LSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQ 459 H+ +++ S+DGQF ++ S D +W++ G GHE V FS D+R Sbjct: 1462 RHYEKNIFAAEFSADGQFIVTASDDNTAGIWEI-VGREVGICRGHEGPVYFAQFSADSRY 1520 Query: 460 IVSASRDRTIKLWNTLGECKYTIGG 534 I++AS D T ++W+ LG T+ G Sbjct: 1521 ILTASVDNTARIWDFLGRPLLTLAG 1545 Score = 61.2 bits (147), Expect = 2e-09 Identities = 41/141 (29%), Positives = 63/141 (44%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 +RGH D V ++ + F+V+S +D + +W+ G GH Sbjct: 1092 LRGHEDWVRSVHFS-PHHQFLVTSGQDNTARIWNFA-------------GEQLTLCQGHA 1137 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSA 471 +V++ + GQ L+ S DG RLWDL G GH V + FS D + IV+ Sbjct: 1138 DWVRNAEFNCHGQILLTASRDGTARLWDLE-GREIGLCQGHTSWVRNAQFSPDGQWIVTC 1196 Query: 472 SRDRTIKLWNTLGECKYTIGG 534 S D T +LW+ +C + G Sbjct: 1197 SADGTARLWDLSSQCFAVLKG 1217 Score = 60.8 bits (146), Expect = 2e-09 Identities = 45/143 (31%), Positives = 63/143 (44%) Frame = +1 Query: 106 GVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTG 285 G+ RGH V D S +I+++S D + +WD G P L G Sbjct: 1500 GICRGHEGPVYFAQFSAD-SRYILTASVDNTARIWDFL-------------GRPLLTLAG 1545 Query: 286 HGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIV 465 H V S +G + S D RLWD S G T GH+ V +V +S D + +V Sbjct: 1546 HQSIVYQARFSPEGNLIATVSADHTARLWDRS-GKTVAVLYGHQGLVGTVDWSPDGQMLV 1604 Query: 466 SASRDRTIKLWNTLGECKYTIGG 534 +AS D T +LW+ G T+ G Sbjct: 1605 TASNDGTARLWDLSGRELLTLEG 1627 Score = 60.5 bits (145), Expect = 3e-09 Identities = 41/137 (29%), Positives = 62/137 (45%) Frame = +1 Query: 106 GVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTG 285 G +RGH+ + +D IV+ S D + +W ++ G L G Sbjct: 1254 GTLRGHDHNIHGARFSLDGQK-IVTYSTDNTARLW-------------TKEGTLLTILRG 1299 Query: 286 HGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIV 465 H V D S+DG+F + S D R WD+S T GH V + F+ +++ Sbjct: 1300 HQKEVYDADFSADGRFVFTVSADQTARQWDISQKDTIT-LTGHSHWVRNAHFNPKGDRLL 1358 Query: 466 SASRDRTIKLWNTLGEC 516 + SRD+T +LW T GEC Sbjct: 1359 TVSRDKTARLWTTEGEC 1375 Score = 60.1 bits (144), Expect = 4e-09 Identities = 38/121 (31%), Positives = 64/121 (52%) Frame = +1 Query: 172 IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSW 351 ++++SRD + +WDL E G+ GH +V++ S DGQ+ ++ S Sbjct: 1152 LLTASRDGTARLWDLEG---------REIGL----CQGHTSWVRNAQFSPDGQWIVTCSA 1198 Query: 352 DGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNTLGECKYTIG 531 DG RLWDLS+ GH+ V + +S D + I+++S D T ++W+ G+C T+ Sbjct: 1199 DGTARLWDLSSQCFA-VLKGHQNWVNNALWSPDGQHIITSSSDGTARVWSRHGKCLGTLR 1257 Query: 532 G 534 G Sbjct: 1258 G 1258 Score = 58.2 bits (139), Expect = 2e-08 Identities = 38/114 (33%), Positives = 60/114 (52%), Gaps = 1/114 (0%) Frame = +1 Query: 172 IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSW 351 +++ SRDK+ +W A L H +V++ S DGQ+ ++GS Sbjct: 1357 LLTVSRDKTARLWTTEGECVAV-------------LADHQGWVREGQFSPDGQWIVTGSA 1403 Query: 352 DGELRLWD-LSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNTLG 510 D +LW+ L +T R GH+ VL+V FS D++ IV+AS+D T ++WN G Sbjct: 1404 DKTAQLWNVLGKKLTVLR--GHQDAVLNVRFSPDSQYIVTASKDGTARVWNNTG 1455 Score = 57.4 bits (137), Expect = 3e-08 Identities = 43/143 (30%), Positives = 64/143 (44%), Gaps = 1/143 (0%) Frame = +1 Query: 109 VMRGH-NDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTG 285 V++GH N V A+ +P + I++SS D + VW S +G L G Sbjct: 1214 VLKGHQNWVNNALWSP--DGQHIITSSSDGTARVW-------------SRHGKCLGTLRG 1258 Query: 286 HGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIV 465 H H + S DGQ ++ S D RLW G GH+K+V FS D R + Sbjct: 1259 HDHNIHGARFSLDGQKIVTYSTDNTARLWT-KEGTLLTILRGHQKEVYDADFSADGRFVF 1317 Query: 466 SASRDRTIKLWNTLGECKYTIGG 534 + S D+T + W+ + T+ G Sbjct: 1318 TVSADQTARQWDISQKDTITLTG 1340 Score = 56.2 bits (134), Expect = 6e-08 Identities = 45/130 (34%), Positives = 58/130 (44%), Gaps = 1/130 (0%) Frame = +1 Query: 112 MRGHNDVV-TAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 + GH +V A +P N I + S D + +WD + A L GH Sbjct: 1543 LAGHQSIVYQARFSPEGN--LIATVSADHTARLWDRSGKTVAV-------------LYGH 1587 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVS 468 V V S DGQ ++ S DG RLWDLS G GH V S FS D R +++ Sbjct: 1588 QGLVGTVDWSPDGQMLVTASNDGTARLWDLS-GRELLTLEGHGNWVRSAEFSPDGRWVLT 1646 Query: 469 ASRDRTIKLW 498 +S D T KLW Sbjct: 1647 SSADGTAKLW 1656 Score = 55.8 bits (133), Expect = 8e-08 Identities = 41/135 (30%), Positives = 63/135 (46%) Frame = +1 Query: 109 VMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 ++RGH V D F+ + S D++ WD++ +DT + LTGH Sbjct: 1296 ILRGHQKEVYDADFSADGR-FVFTVSADQTARQWDISQ-----KDTIT--------LTGH 1341 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVS 468 H+V++ + G L+ S D RLW + G H+ V FS D + IV+ Sbjct: 1342 SHWVRNAHFNPKGDRLLTVSRDKTARLWT-TEGECVAVLADHQGWVREGQFSPDGQWIVT 1400 Query: 469 ASRDRTIKLWNTLGE 513 S D+T +LWN LG+ Sbjct: 1401 GSADKTAQLWNVLGK 1415 Score = 48.5 bits (114), Expect = 1e-05 Identities = 33/105 (31%), Positives = 51/105 (48%), Gaps = 6/105 (5%) Frame = +1 Query: 217 TNPIQATQDTS------SEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDL 378 T P+ T T+ S +G L GH + + S+DGQ+ + S D ++LW Sbjct: 1025 TPPLVLTATTNGIAYLWSFHGELINVLRGHQEAITALDWSADGQYFATASADHTVKLWQR 1084 Query: 379 STGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNTLGE 513 G GHE V SV FS ++ +V++ +D T ++WN GE Sbjct: 1085 H-GEEVATLRGHEDWVRSVHFSPHHQFLVTSGQDNTARIWNFAGE 1128 Score = 44.7 bits (104), Expect = 2e-04 Identities = 27/92 (29%), Positives = 44/92 (47%) Frame = +1 Query: 109 VMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 V+ GH +V + D +V++S D + +WDL+ G L GH Sbjct: 1583 VLYGHQGLVGTVDWSPDGQ-MLVTASNDGTARLWDLS-------------GRELLTLEGH 1628 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDLST 384 G++V+ S DG++ L+ S DG +LW + T Sbjct: 1629 GNWVRSAEFSPDGRWVLTSSADGTAKLWPVKT 1660 Score = 36.2 bits (82), Expect = 0.063 Identities = 20/66 (30%), Positives = 33/66 (50%) Frame = +1 Query: 337 LSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNTLGEC 516 L+ + +G LW G GH++ + ++ +S D + +AS D T+KLW GE Sbjct: 1030 LTATTNGIAYLWSFH-GELINVLRGHQEAITALDWSADGQYFATASADHTVKLWQRHGEE 1088 Query: 517 KYTIGG 534 T+ G Sbjct: 1089 VATLRG 1094
>GBB2_TOBAC (P93398) Guanine nucleotide-binding protein beta subunit 2| Length = 377 Score = 63.5 bits (153), Expect = 4e-10 Identities = 42/133 (31%), Positives = 71/133 (53%), Gaps = 2/133 (1%) Frame = +1 Query: 109 VMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 ++ GH V++ D +++SS D++ ++WD+T ++ +S +G F+ +GH Sbjct: 151 MLSGHKGYVSSCQYVPDEDTHVITSSGDQTCVLWDITTGLR-----TSVFGGEFQ--SGH 203 Query: 289 GHFVQDV-VLSSDGQFALSGSWDGELRLWDLSTGVTTRR-FVGHEKDVLSVAFSIDNRQI 462 VQ V + SS+ + +SGS D RLWD +R F GHE DV +V F D + Sbjct: 204 TADVQSVSISSSNPRLFVSGSCDSTARLWDTRVASRAQRTFYGHEGDVNTVKFFPDGNRF 263 Query: 463 VSASRDRTIKLWN 501 + S D T +L++ Sbjct: 264 GTGSDDGTCRLFD 276 Score = 47.0 bits (110), Expect = 4e-05 Identities = 54/197 (27%), Positives = 80/197 (40%), Gaps = 46/197 (23%) Frame = +1 Query: 52 RSLRHTTMAGAQESLVYAGVMRGHNDVVTAIA-TPIDNSPFIVSSSRDKSLLVWD-LTNP 225 RS T + LV +++GH V ++ TP N IVS+S+D L+VW+ LT+ Sbjct: 41 RSQGKTPVIFGPTDLVCCRILQGHTGKVYSLDWTPEKNR--IVSASQDGRLIVWNALTSQ 98 Query: 226 -------------------------------------IQATQDTSSEYGVPFRRLTGHGH 294 + + D + V R L+GH Sbjct: 99 KTHAIKLPCAWVMTCAFSPSGQSVACGGLDSVCSIFNLNSPIDKDGNHPVS-RMLSGHKG 157 Query: 295 FVQDV-VLSSDGQFALSGSWDGELRLWDLSTGVTTRRF-----VGHEKDVLSVAFSIDN- 453 +V + + ++ S D LWD++TG+ T F GH DV SV+ S N Sbjct: 158 YVSSCQYVPDEDTHVITSSGDQTCVLWDITTGLRTSVFGGEFQSGHTADVQSVSISSSNP 217 Query: 454 RQIVSASRDRTIKLWNT 504 R VS S D T +LW+T Sbjct: 218 RLFVSGSCDSTARLWDT 234 Score = 44.3 bits (103), Expect = 2e-04 Identities = 40/148 (27%), Positives = 58/148 (39%), Gaps = 5/148 (3%) Frame = +1 Query: 79 GAQESLVYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEY 258 G + S+ GH V +++ N VS S D + +WD +A Sbjct: 189 GLRTSVFGGEFQSGHTADVQSVSISSSNPRLFVSGSCDSTARLWDTRVASRAQ------- 241 Query: 259 GVPFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFV-----GHEKD 423 R GH V V DG +GS DG RL+D+ TG + + G Sbjct: 242 ----RTFYGHEGDVNTVKFFPDGNRFGTGSDDGTCRLFDIRTGHQLQVYYQPHGDGDIPH 297 Query: 424 VLSVAFSIDNRQIVSASRDRTIKLWNTL 507 V S+AFSI R + + +W+TL Sbjct: 298 VTSMAFSISGRLLFVGYSNGDCYVWDTL 325 Score = 29.6 bits (65), Expect = 5.9 Identities = 15/40 (37%), Positives = 23/40 (57%) Frame = +1 Query: 388 VTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNTL 507 V R GH V S+ ++ + +IVSAS+D + +WN L Sbjct: 56 VCCRILQGHTGKVYSLDWTPEKNRIVSASQDGRLIVWNAL 95
>TAF5_YEAST (P38129) Transcription initiation factor TFIID subunit 5| (TBP-associated factor 5) (TBP-associated factor 90 kDa) (TAFII-90) Length = 798 Score = 63.5 bits (153), Expect = 4e-10 Identities = 38/130 (29%), Positives = 66/130 (50%), Gaps = 1/130 (0%) Frame = +1 Query: 115 RGHNDVVTAIA-TPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 +GHN V ++ +P+ + + ++S D++ +W S ++ P R GH Sbjct: 564 KGHNHPVWDVSFSPLGH--YFATASHDQTARLW------------SCDHIYPLRIFAGHL 609 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSA 471 + V V +G + +GS D R+WD+STG + R F+GH V+S+A D R + + Sbjct: 610 NDVDCVSFHPNGCYVFTGSSDKTCRMWDVSTGDSVRLFLGHTAPVISIAVCPDGRWLSTG 669 Query: 472 SRDRTIKLWN 501 S D I +W+ Sbjct: 670 SEDGIINVWD 679 Score = 60.8 bits (146), Expect = 2e-09 Identities = 36/133 (27%), Positives = 66/133 (49%), Gaps = 2/133 (1%) Frame = +1 Query: 109 VMRGH-NDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTG 285 + GH NDV P N ++ + S DK+ +WD++ G R G Sbjct: 604 IFAGHLNDVDCVSFHP--NGCYVFTGSSDKTCRMWDVST------------GDSVRLFLG 649 Query: 286 HGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKD-VLSVAFSIDNRQI 462 H V + + DG++ +GS DG + +WD+ TG ++ GH K+ + S+++S + + Sbjct: 650 HTAPVISIAVCPDGRWLSTGSEDGIINVWDIGTGKRLKQMRGHGKNAIYSLSYSKEGNVL 709 Query: 463 VSASRDRTIKLWN 501 +S D T+++W+ Sbjct: 710 ISGGADHTVRVWD 722 Score = 58.9 bits (141), Expect = 9e-09 Identities = 34/120 (28%), Positives = 52/120 (43%), Gaps = 5/120 (4%) Frame = +1 Query: 157 DNSPFIVSSSRDKSLLVWDL-----TNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSS 321 D+ + +D + +W L NP A + + + L GH V S Sbjct: 476 DDCRIAAAGFQDSYIKIWSLDGSSLNNPNIALNNNDKDEDPTCKTLVGHSGTVYSTSFSP 535 Query: 322 DGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN 501 D ++ LSGS D +RLW + T + GH V V+FS +AS D+T +LW+ Sbjct: 536 DNKYLLSGSEDKTVRLWSMDTHTALVSYKGHNHPVWDVSFSPLGHYFATASHDQTARLWS 595 Score = 38.5 bits (88), Expect = 0.013 Identities = 34/131 (25%), Positives = 55/131 (41%), Gaps = 7/131 (5%) Frame = +1 Query: 118 GHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG-H 294 GH V +IA D ++ + S D + VWD+ G +++ GHG + Sbjct: 649 GHTAPVISIAVCPDGR-WLSTGSEDGIINVWDIGT------------GKRLKQMRGHGKN 695 Query: 295 FVQDVVLSSDGQFALSGSWDGELRLWDLSTGVT------TRRFVGHEKDVLSVAFSIDNR 456 + + S +G +SG D +R+WDL T F+G+ DV + N+ Sbjct: 696 AIYSLSYSKEGNVLISGGADHTVRVWDLKKATTEPSAEPDEPFIGYLGDVTASI----NQ 751 Query: 457 QIVSASRDRTI 489 I R RT+ Sbjct: 752 DIKEYGRRRTV 762
>WD51A_HUMAN (Q8NBT0) WD-repeat protein 51A| Length = 407 Score = 63.5 bits (153), Expect = 4e-10 Identities = 43/130 (33%), Positives = 59/130 (45%) Frame = +1 Query: 115 RGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGH 294 +GH D VT + I N+ + S S D L+VW + +A R TGH Sbjct: 16 KGHRDAVTCVDFSI-NTKQLASGSMDSCLMVWHMKPQSRAY------------RFTGHKD 62 Query: 295 FVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSAS 474 V V S G SGS D +R+W + + F H V SV F D + V+AS Sbjct: 63 AVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTAS 122 Query: 475 RDRTIKLWNT 504 D+T+K+W T Sbjct: 123 DDKTVKVWAT 132 Score = 48.5 bits (114), Expect = 1e-05 Identities = 29/83 (34%), Positives = 39/83 (46%), Gaps = 2/83 (2%) Frame = +1 Query: 271 RRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSID 450 R GH V V S + + SGS D L +W + RF GH+ V V FS Sbjct: 13 RHFKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPS 72 Query: 451 NRQIVSASRDRTIKLW--NTLGE 513 + S SRD+T+++W N GE Sbjct: 73 GHLLASGSRDKTVRIWVPNVKGE 95 Score = 47.4 bits (111), Expect = 3e-05 Identities = 36/131 (27%), Positives = 57/131 (43%) Frame = +1 Query: 109 VMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 V R H V ++ D F+ +S DK++ VW AT + L+ H Sbjct: 98 VFRAHTATVRSVHFCSDGQSFVTASD-DKTVKVW-------ATHRQKFLFS-----LSQH 144 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVS 468 ++V+ S DG+ +S S D ++LWD S+ + H V V F I + Sbjct: 145 INWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDFHPSGTCIAA 204 Query: 469 ASRDRTIKLWN 501 A D T+K+W+ Sbjct: 205 AGMDNTVKVWD 215 Score = 46.6 bits (109), Expect = 5e-05 Identities = 32/125 (25%), Positives = 58/125 (46%), Gaps = 1/125 (0%) Frame = +1 Query: 172 IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSW 351 IVS+S DK++ +WD +++++ Y HG FV V G + Sbjct: 160 IVSASDDKTVKLWD-----KSSRECVHSY-------CEHGGFVTYVDFHPSGTCIAAAGM 207 Query: 352 DGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNTL-GECKYTI 528 D +++WD+ T + + H V ++F +++AS D T+K+ + + G YT+ Sbjct: 208 DNTVKVWDVRTHRLLQHYQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTL 267 Query: 529 GGDLG 543 G G Sbjct: 268 HGHQG 272 Score = 36.6 bits (83), Expect = 0.049 Identities = 25/111 (22%), Positives = 42/111 (37%) Frame = +1 Query: 172 IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSW 351 I ++ D ++ VWD+ T Y + H V + G + ++ S Sbjct: 202 IAAAGMDNTVKVWDVR-----THRLLQHYQL-------HSAAVNGLSFHPSGNYLITASS 249 Query: 352 DGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNT 504 D L++ DL G GH+ +VAFS S D + +W + Sbjct: 250 DSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVWKS 300
>WDR48_CHICK (Q5F3K4) WD-repeat protein 48| Length = 678 Score = 63.2 bits (152), Expect = 5e-10 Identities = 38/130 (29%), Positives = 64/130 (49%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 +R H D V A+A D + S+ D+ + +WD+ T T+S V L+G+ Sbjct: 113 LRTHKDYVKALAYAKDKE-LVASAGLDRQIFLWDVNT---LTALTASNNTVTTSSLSGNK 168 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSA 471 + + ++ G +SGS + LR+WD T + GH +V ++ + D Q +S Sbjct: 169 DSIYSLAMNQMGTVIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLNRDGTQCLSG 228 Query: 472 SRDRTIKLWN 501 S D TI+LW+ Sbjct: 229 SSDGTIRLWS 238 Score = 49.3 bits (116), Expect = 7e-06 Identities = 39/140 (27%), Positives = 60/140 (42%) Frame = +1 Query: 70 TMAGAQESLVYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTS 249 T A + V + G+ D + ++A IVS S +K L VWD + Sbjct: 150 TALTASNNTVTTSSLSGNKDSIYSLAMN-QMGTVIVSGSTEKVLRVWDPRTCAK------ 202 Query: 250 SEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVL 429 +L GH V+ ++L+ DG LSGS DG +RLW L + H++ V Sbjct: 203 ------LMKLKGHTDNVKALLLNRDGTQCLSGSSDGTIRLWSLGQQRCIATYRVHDEGVW 256 Query: 430 SVAFSIDNRQIVSASRDRTI 489 ++ + + S RDR I Sbjct: 257 ALQVNEAFTHVYSGGRDRKI 276 Score = 48.5 bits (114), Expect = 1e-05 Identities = 31/114 (27%), Positives = 53/114 (46%), Gaps = 2/114 (1%) Frame = +1 Query: 172 IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSW 351 + ++ RD + +W + Q S E+ H +V D+VL +G+ +S S Sbjct: 45 LFTAGRDSIIRIWSVNQHKQDPYIASMEH---------HTDWVNDIVLCCNGKTLISASS 95 Query: 352 DGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLW--NTL 507 D +++W+ G H+ V ++A++ D + SA DR I LW NTL Sbjct: 96 DTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDVNTL 149
>GBB1_TOBAC (P93397) Guanine nucleotide-binding protein beta subunit 1| Length = 377 Score = 63.2 bits (152), Expect = 5e-10 Identities = 42/133 (31%), Positives = 71/133 (53%), Gaps = 2/133 (1%) Frame = +1 Query: 109 VMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 ++ GH V++ D +++SS D++ ++WD+T ++ +S +G F+ +GH Sbjct: 151 MLSGHKGYVSSCQYVPDEDTHLITSSGDQTCVLWDITTGLR-----TSVFGGEFQ--SGH 203 Query: 289 GHFVQDV-VLSSDGQFALSGSWDGELRLWDLSTGVTTRR-FVGHEKDVLSVAFSIDNRQI 462 VQ V + SS+ + +SGS D RLWD +R F GHE DV +V F D + Sbjct: 204 TADVQSVSISSSNPRLFVSGSCDTTARLWDTRVASRAQRTFYGHEGDVNTVKFFPDGNRF 263 Query: 463 VSASRDRTIKLWN 501 + S D T +L++ Sbjct: 264 GTGSEDGTCRLFD 276 Score = 47.0 bits (110), Expect = 4e-05 Identities = 54/197 (27%), Positives = 80/197 (40%), Gaps = 46/197 (23%) Frame = +1 Query: 52 RSLRHTTMAGAQESLVYAGVMRGHNDVVTAIA-TPIDNSPFIVSSSRDKSLLVWD-LTNP 225 RS T + LV +++GH V ++ TP N IVS+S+D L+VW+ LT+ Sbjct: 41 RSQGKTPVTFGPTDLVCCRILQGHTGKVYSLDWTPEKNR--IVSASQDGRLIVWNALTSQ 98 Query: 226 -------------------------------------IQATQDTSSEYGVPFRRLTGHGH 294 + + D + V R L+GH Sbjct: 99 KTHAIKLPCAWVMTCAFSPSGQSVACGGLDSVCSIFNLNSPIDKDGNHPVS-RMLSGHKG 157 Query: 295 FVQDV-VLSSDGQFALSGSWDGELRLWDLSTGVTTRRF-----VGHEKDVLSVAFSIDN- 453 +V + + ++ S D LWD++TG+ T F GH DV SV+ S N Sbjct: 158 YVSSCQYVPDEDTHLITSSGDQTCVLWDITTGLRTSVFGGEFQSGHTADVQSVSISSSNP 217 Query: 454 RQIVSASRDRTIKLWNT 504 R VS S D T +LW+T Sbjct: 218 RLFVSGSCDTTARLWDT 234 Score = 41.2 bits (95), Expect = 0.002 Identities = 39/148 (26%), Positives = 57/148 (38%), Gaps = 5/148 (3%) Frame = +1 Query: 79 GAQESLVYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEY 258 G + S+ GH V +++ N VS S D + +WD +A Sbjct: 189 GLRTSVFGGEFQSGHTADVQSVSISSSNPRLFVSGSCDTTARLWDTRVASRAQ------- 241 Query: 259 GVPFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFV-----GHEKD 423 R GH V V DG +GS DG RL+D+ T + + G Sbjct: 242 ----RTFYGHEGDVNTVKFFPDGNRFGTGSEDGTCRLFDIRTEHQLQVYYQPHGDGDIPH 297 Query: 424 VLSVAFSIDNRQIVSASRDRTIKLWNTL 507 V S+AFSI R + + +W+TL Sbjct: 298 VTSMAFSISGRLLFVGYSNGDCYVWDTL 325 Score = 29.6 bits (65), Expect = 5.9 Identities = 15/40 (37%), Positives = 23/40 (57%) Frame = +1 Query: 388 VTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNTL 507 V R GH V S+ ++ + +IVSAS+D + +WN L Sbjct: 56 VCCRILQGHTGKVYSLDWTPEKNRIVSASQDGRLIVWNAL 95
>WDR48_PONPY (Q5RAW8) WD-repeat protein 48| Length = 677 Score = 63.2 bits (152), Expect = 5e-10 Identities = 38/130 (29%), Positives = 64/130 (49%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 +R H D V A+A D + S+ D+ + +WD+ T T+S V L+G+ Sbjct: 113 LRTHKDYVKALAYAKDKE-LVASAGLDRQIFLWDVNT---LTALTASNNTVTTSSLSGNK 168 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSA 471 + + ++ G +SGS + LR+WD T + GH +V ++ + D Q +S Sbjct: 169 DSIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLNRDGTQCLSG 228 Query: 472 SRDRTIKLWN 501 S D TI+LW+ Sbjct: 229 SSDGTIRLWS 238 Score = 49.3 bits (116), Expect = 7e-06 Identities = 39/140 (27%), Positives = 60/140 (42%) Frame = +1 Query: 70 TMAGAQESLVYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTS 249 T A + V + G+ D + ++A IVS S +K L VWD + Sbjct: 150 TALTASNNTVTTSSLSGNKDSIYSLAMN-QLGTIIVSGSTEKVLRVWDPRTCAK------ 202 Query: 250 SEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVL 429 +L GH V+ ++L+ DG LSGS DG +RLW L + H++ V Sbjct: 203 ------LMKLKGHTDNVKALLLNRDGTQCLSGSSDGTIRLWSLGQQRCIATYRVHDEGVW 256 Query: 430 SVAFSIDNRQIVSASRDRTI 489 ++ + + S RDR I Sbjct: 257 ALQVNDAFTHVYSGGRDRKI 276 Score = 48.5 bits (114), Expect = 1e-05 Identities = 31/114 (27%), Positives = 53/114 (46%), Gaps = 2/114 (1%) Frame = +1 Query: 172 IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSW 351 + ++ RD + +W + Q S E+ H +V D+VL +G+ +S S Sbjct: 45 LFTAGRDSIIRIWSVNQHKQDPYIASMEH---------HTDWVNDIVLCCNGKTLISASS 95 Query: 352 DGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLW--NTL 507 D +++W+ G H+ V ++A++ D + SA DR I LW NTL Sbjct: 96 DTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDVNTL 149
>WDR48_HUMAN (Q8TAF3) WD-repeat protein 48 (WD repeat endosomal protein) (p80)| Length = 677 Score = 63.2 bits (152), Expect = 5e-10 Identities = 38/130 (29%), Positives = 64/130 (49%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 +R H D V A+A D + S+ D+ + +WD+ T T+S V L+G+ Sbjct: 113 LRTHKDYVKALAYAKDKE-LVASAGLDRQIFLWDVNT---LTALTASNNTVTTSSLSGNK 168 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSA 471 + + ++ G +SGS + LR+WD T + GH +V ++ + D Q +S Sbjct: 169 DSIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLNRDGTQCLSG 228 Query: 472 SRDRTIKLWN 501 S D TI+LW+ Sbjct: 229 SSDGTIRLWS 238 Score = 49.3 bits (116), Expect = 7e-06 Identities = 39/140 (27%), Positives = 60/140 (42%) Frame = +1 Query: 70 TMAGAQESLVYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTS 249 T A + V + G+ D + ++A IVS S +K L VWD + Sbjct: 150 TALTASNNTVTTSSLSGNKDSIYSLAMN-QLGTIIVSGSTEKVLRVWDPRTCAK------ 202 Query: 250 SEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVL 429 +L GH V+ ++L+ DG LSGS DG +RLW L + H++ V Sbjct: 203 ------LMKLKGHTDNVKALLLNRDGTQCLSGSSDGTIRLWSLGQQRCIATYRVHDEGVW 256 Query: 430 SVAFSIDNRQIVSASRDRTI 489 ++ + + S RDR I Sbjct: 257 ALQVNDAFTHVYSGGRDRKI 276 Score = 48.5 bits (114), Expect = 1e-05 Identities = 31/114 (27%), Positives = 53/114 (46%), Gaps = 2/114 (1%) Frame = +1 Query: 172 IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSW 351 + ++ RD + +W + Q S E+ H +V D+VL +G+ +S S Sbjct: 45 LFTAGRDSIIRIWSVNQHKQDPYIASMEH---------HTDWVNDIVLCCNGKTLISASS 95 Query: 352 DGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLW--NTL 507 D +++W+ G H+ V ++A++ D + SA DR I LW NTL Sbjct: 96 DTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDVNTL 149
>STRN_HUMAN (O43815) Striatin| Length = 780 Score = 63.2 bits (152), Expect = 5e-10 Identities = 43/143 (30%), Positives = 73/143 (51%), Gaps = 12/143 (8%) Frame = +1 Query: 112 MRGHNDVVTAIAT-PIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 +R H D + A+A PI+ P ++++S D +L +W+L A + TS + P H Sbjct: 459 LRSHFDGIRALAFHPIE--PVLITASEDHTLKMWNLQKTAPAKKSTSLDVE-PIYTFRAH 515 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDLST-----------GVTTRRFVGHEKDVLSV 435 V VV+SS+G+ SG DG ++ W+ + V +GH V + Sbjct: 516 KGPVLCVVMSSNGEQCYSGGTDGLIQGWNTTNPNIDPYDSYDPSVLRGPLLGHTDAVWGL 575 Query: 436 AFSIDNRQIVSASRDRTIKLWNT 504 A+S +++++S S D T++LWNT Sbjct: 576 AYSAAHQRLLSCSADGTLRLWNT 598 Score = 38.9 bits (89), Expect = 0.010 Identities = 22/78 (28%), Positives = 36/78 (46%), Gaps = 4/78 (5%) Frame = +1 Query: 277 LTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGH----EKDVLSVAFS 444 + H V + + +G + +SGS D +RLW+L + + F H E+ + VAF Sbjct: 702 MVAHLEAVTSLAVDPNGLYLMSGSHDCSIRLWNLESKTCIQEFTAHRKKFEESIHDVAFH 761 Query: 445 IDNRQIVSASRDRTIKLW 498 I SA D K++ Sbjct: 762 PSKCYIASAGADALAKVF 779 Score = 33.9 bits (76), Expect = 0.31 Identities = 16/50 (32%), Positives = 27/50 (54%) Frame = +1 Query: 352 DGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN 501 D ++ +D +TG V H + V S+A + ++S S D +I+LWN Sbjct: 685 DRHIKFYDNNTGKLIHSMVAHLEAVTSLAVDPNGLYLMSGSHDCSIRLWN 734
>WDR48_MACFA (Q4R2Z6) WD-repeat protein 48| Length = 622 Score = 63.2 bits (152), Expect = 5e-10 Identities = 38/130 (29%), Positives = 64/130 (49%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 +R H D V A+A D + S+ D+ + +WD+ T T+S V L+G+ Sbjct: 113 LRTHKDYVKALAYAKDKE-LVASAGLDRQIFLWDVNT---LTALTASNNTVTTSSLSGNK 168 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSA 471 + + ++ G +SGS + LR+WD T + GH +V ++ + D Q +S Sbjct: 169 DSIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLNRDGTQCLSG 228 Query: 472 SRDRTIKLWN 501 S D TI+LW+ Sbjct: 229 SSDGTIRLWS 238 Score = 49.3 bits (116), Expect = 7e-06 Identities = 39/140 (27%), Positives = 60/140 (42%) Frame = +1 Query: 70 TMAGAQESLVYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTS 249 T A + V + G+ D + ++A IVS S +K L VWD + Sbjct: 150 TALTASNNTVTTSSLSGNKDSIYSLAMN-QLGTIIVSGSTEKVLRVWDPRTCAK------ 202 Query: 250 SEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVL 429 +L GH V+ ++L+ DG LSGS DG +RLW L + H++ V Sbjct: 203 ------LMKLKGHTDNVKALLLNRDGTQCLSGSSDGTIRLWSLGQQRCIATYRVHDEGVW 256 Query: 430 SVAFSIDNRQIVSASRDRTI 489 ++ + + S RDR I Sbjct: 257 ALQVNDAFTHVYSGGRDRKI 276 Score = 48.5 bits (114), Expect = 1e-05 Identities = 31/114 (27%), Positives = 53/114 (46%), Gaps = 2/114 (1%) Frame = +1 Query: 172 IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSW 351 + ++ RD + +W + Q S E+ H +V D+VL +G+ +S S Sbjct: 45 LFTAGRDSIIRIWSVNQHKQDPYIASMEH---------HTDWVNDIVLCCNGKTLISASS 95 Query: 352 DGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLW--NTL 507 D +++W+ G H+ V ++A++ D + SA DR I LW NTL Sbjct: 96 DTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDVNTL 149
>KTNB1_HUMAN (Q9BVA0) Katanin p80 WD40-containing subunit B1 (Katanin p80| subunit B1) (p80 katanin) Length = 655 Score = 62.8 bits (151), Expect = 6e-10 Identities = 45/147 (30%), Positives = 67/147 (45%), Gaps = 3/147 (2%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSP--FIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTG 285 + GH V ++ N+P IV+ S+ S+ VWDL E R L G Sbjct: 59 LTGHTSPVESVRL---NTPEELIVAGSQSGSIRVWDL------------EAAKILRTLMG 103 Query: 286 HGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIV 465 H + + G+F SGS D ++LWD+ R+ GH + V + FS D + + Sbjct: 104 HKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLA 163 Query: 466 SASRDRTIKLWN-TLGECKYTIGGDLG 543 SA+ D T+KLW+ T G+ G G Sbjct: 164 SAADDHTVKLWDLTAGKMMSEFPGHTG 190 Score = 58.2 bits (139), Expect = 2e-08 Identities = 35/111 (31%), Positives = 53/111 (47%) Frame = +1 Query: 169 FIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGS 348 F+ S S+D ++ +WD+ G FR GH V+ + S DG++ S + Sbjct: 119 FVASGSQDTNIKLWDIRRK-----------GCVFR-YRGHSQAVRCLRFSPDGKWLASAA 166 Query: 349 WDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN 501 D ++LWDL+ G F GH V V F + + S S DRTI+ W+ Sbjct: 167 DDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWD 217 Score = 37.4 bits (85), Expect = 0.028 Identities = 32/122 (26%), Positives = 46/122 (37%) Frame = +1 Query: 115 RGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGH 294 RGH+ V + D ++ S++ D ++ +WDLT G GH Sbjct: 144 RGHSQAVRCLRFSPDGK-WLASAADDHTVKLWDLTA------------GKMMSEFPGHTG 190 Query: 295 FVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSAS 474 V V + SGS D +R WDL G V SV F+ D + S Sbjct: 191 PVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDGCCLYSGC 250 Query: 475 RD 480 +D Sbjct: 251 QD 252 Score = 34.7 bits (78), Expect = 0.18 Identities = 19/78 (24%), Positives = 35/78 (44%), Gaps = 1/78 (1%) Frame = +1 Query: 271 RRLTGHGHFVQDVVLS-SDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSI 447 + + H V +VL + G+ +G D + LW ++ GH V SV + Sbjct: 14 QEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNT 73 Query: 448 DNRQIVSASRDRTIKLWN 501 IV+ S+ +I++W+ Sbjct: 74 PEELIVAGSQSGSIRVWD 91
>Y143_SYNY3 (P74442) Hypothetical WD-repeat protein slr0143| Length = 1191 Score = 62.8 bits (151), Expect = 6e-10 Identities = 43/141 (30%), Positives = 66/141 (46%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 ++GH D V +++ D + S+SRD+++ +W + G L GH Sbjct: 638 LKGHQDSVYSVSFSPDGE-ILASTSRDRTVRLWHWRS------------GKTLAVLGGHT 684 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSA 471 V D S DGQ +S DG++RLWDL G R+F E V + + + A Sbjct: 685 KSVDDAQFSPDGQTLVSVCRDGQIRLWDLD-GNLIRQFGLPEVAFFGVNWHPNGNLLAVA 743 Query: 472 SRDRTIKLWNTLGECKYTIGG 534 + D T++LW GE K T+ G Sbjct: 744 ADDGTVRLWTPQGEIKATLSG 764 Score = 62.4 bits (150), Expect = 8e-10 Identities = 50/162 (30%), Positives = 67/162 (41%), Gaps = 28/162 (17%) Frame = +1 Query: 109 VMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPI--QATQDTSSEYGVPF---- 270 V+ GH D VT++A + I S+SRD ++ +W + T T S Y V F Sbjct: 555 VLTGHRDGVTSVAIS-SHKNLIASASRDGTVHLWTPQGEFLREFTGHTGSIYRVDFSPNG 613 Query: 271 ----------------------RRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLST 384 + L GH V V S DG+ S S D +RLW + Sbjct: 614 KIFATAGQDQTVKIWDLDGNLLQTLKGHQDSVYSVSFSPDGEILASTSRDRTVRLWHWRS 673 Query: 385 GVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNTLG 510 G T GH K V FS D + +VS RD I+LW+ G Sbjct: 674 GKTLAVLGGHTKSVDDAQFSPDGQTLVSVCRDGQIRLWDLDG 715 Score = 57.4 bits (137), Expect = 3e-08 Identities = 36/115 (31%), Positives = 55/115 (47%) Frame = +1 Query: 190 DKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRL 369 D++L + T+P+ + Q S+ LTGH V V +SS S S DG + L Sbjct: 528 DETLSQYPATSPLVSLQQILSQIAEK-NVLTGHRDGVTSVAISSHKNLIASASRDGTVHL 586 Query: 370 WDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNTLGECKYTIGG 534 W G R F GH + V FS + + +A +D+T+K+W+ G T+ G Sbjct: 587 WT-PQGEFLREFTGHTGSIYRVDFSPNGKIFATAGQDQTVKIWDLDGNLLQTLKG 640 Score = 40.4 bits (93), Expect = 0.003 Identities = 27/109 (24%), Positives = 47/109 (43%) Frame = +1 Query: 211 DLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGV 390 +L +PI S + P R ++ H Q +G G L LW+ G Sbjct: 981 ELNDPIVLALGNSIQRKEPIRSVSLHPTLPQ----------LAAGDEQGNLTLWNFD-GT 1029 Query: 391 TTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNTLGECKYTIGGD 537 R V H + + +S + + ++SA R+ T K+W+ G+ +T+ D Sbjct: 1030 LIRSIVAHGDRLNQLQYSPNGKYLLSAGREGTAKIWSVEGQLLHTLKSD 1078 Score = 36.2 bits (82), Expect = 0.063 Identities = 20/45 (44%), Positives = 21/45 (46%) Frame = +1 Query: 409 GHEKDVLSVAFSIDNRQIVSASRDRTIKLWNTLGECKYTIGGDLG 543 GH V SVA S I SASRD T+ LW GE G G Sbjct: 558 GHRDGVTSVAISSHKNLIASASRDGTVHLWTPQGEFLREFTGHTG 602 Score = 30.0 bits (66), Expect = 4.5 Identities = 20/90 (22%), Positives = 41/90 (45%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 + GH++ VT + D + SSS + S++ W S G ++ G+ Sbjct: 762 LSGHDEFVTRVVFTPDGKQ-LFSSSSNGSVIHW-------------STSGKMLKKYQGYP 807 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLS 381 + + L+S+G G+ + +++WD+S Sbjct: 808 EAIFGLALASNGALLAIGAENNLVKVWDMS 837
>WD51A_BOVIN (Q2TBP4) WD-repeat protein 51A| Length = 407 Score = 62.8 bits (151), Expect = 6e-10 Identities = 41/130 (31%), Positives = 60/130 (46%) Frame = +1 Query: 115 RGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGH 294 +GH D VT++ + N+ + S S D L+VW + +A R GH Sbjct: 16 KGHRDAVTSVDFSL-NTKQLASGSMDSCLMVWHMKPQTRAY------------RFAGHKD 62 Query: 295 FVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSAS 474 V V S G SGS D +R+W + + F H V SV F D + V+AS Sbjct: 63 AVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTAS 122 Query: 475 RDRTIKLWNT 504 D+T+K+W+T Sbjct: 123 DDKTVKVWST 132 Score = 50.4 bits (119), Expect = 3e-06 Identities = 29/83 (34%), Positives = 39/83 (46%), Gaps = 2/83 (2%) Frame = +1 Query: 271 RRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSID 450 R GH V V S + + SGS D L +W + RF GH+ V V FS Sbjct: 13 RHFKGHRDAVTSVDFSLNTKQLASGSMDSCLMVWHMKPQTRAYRFAGHKDAVTCVNFSPS 72 Query: 451 NRQIVSASRDRTIKLW--NTLGE 513 + S SRD+T+++W N GE Sbjct: 73 GHLLASGSRDKTVRIWVPNVKGE 95 Score = 47.8 bits (112), Expect = 2e-05 Identities = 34/125 (27%), Positives = 58/125 (46%), Gaps = 1/125 (0%) Frame = +1 Query: 172 IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSW 351 IVS+S DK++ +WD T+ ++ Y HG FV V G + Sbjct: 160 IVSASDDKTVKLWDKTS-----RECVHSY-------CEHGGFVTYVDFHPSGTCIAAAGM 207 Query: 352 DGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNTL-GECKYTI 528 D +++WD+ T + + H V +++F +V+AS D T+K+ + + G YT+ Sbjct: 208 DNTVKVWDVRTHRLLQHYQLHSAAVNALSFHPSGNYLVTASSDSTLKILDLMEGRLLYTL 267 Query: 529 GGDLG 543 G G Sbjct: 268 HGHQG 272 Score = 45.4 bits (106), Expect = 1e-04 Identities = 34/131 (25%), Positives = 56/131 (42%) Frame = +1 Query: 109 VMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 V R H V ++ D F+ +S DK++ VW S+ L+ H Sbjct: 98 VFRAHTATVRSVHFCSDGQSFVTASD-DKTVKVW------------STHRQKFLFSLSQH 144 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVS 468 ++V+ S DG+ +S S D ++LWD ++ + H V V F I + Sbjct: 145 INWVRCAKFSPDGRLIVSASDDKTVKLWDKTSRECVHSYCEHGGFVTYVDFHPSGTCIAA 204 Query: 469 ASRDRTIKLWN 501 A D T+K+W+ Sbjct: 205 AGMDNTVKVWD 215 Score = 35.8 bits (81), Expect = 0.083 Identities = 25/111 (22%), Positives = 42/111 (37%) Frame = +1 Query: 172 IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSW 351 I ++ D ++ VWD+ T Y + H V + G + ++ S Sbjct: 202 IAAAGMDNTVKVWDVR-----THRLLQHYQL-------HSAAVNALSFHPSGNYLVTASS 249 Query: 352 DGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNT 504 D L++ DL G GH+ +VAFS S D + +W + Sbjct: 250 DSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVWKS 300
>KTNB1_MOUSE (Q8BG40) Katanin p80 WD40-containing subunit B1 (Katanin p80| subunit B1) (p80 katanin) Length = 658 Score = 62.8 bits (151), Expect = 6e-10 Identities = 45/147 (30%), Positives = 67/147 (45%), Gaps = 3/147 (2%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSP--FIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTG 285 + GH V ++ N+P IV+ S+ S+ VWDL E R L G Sbjct: 59 LTGHTSPVESVRL---NTPEELIVAGSQSGSIRVWDL------------EAAKILRTLMG 103 Query: 286 HGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIV 465 H + + G+F SGS D ++LWD+ R+ GH + V + FS D + + Sbjct: 104 HKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLA 163 Query: 466 SASRDRTIKLWN-TLGECKYTIGGDLG 543 SA+ D T+KLW+ T G+ G G Sbjct: 164 SAADDHTVKLWDLTAGKMMSEFPGHTG 190 Score = 58.2 bits (139), Expect = 2e-08 Identities = 35/111 (31%), Positives = 53/111 (47%) Frame = +1 Query: 169 FIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGS 348 F+ S S+D ++ +WD+ G FR GH V+ + S DG++ S + Sbjct: 119 FVASGSQDTNIKLWDIRRK-----------GCVFR-YRGHSQAVRCLRFSPDGKWLASAA 166 Query: 349 WDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN 501 D ++LWDL+ G F GH V V F + + S S DRTI+ W+ Sbjct: 167 DDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWD 217 Score = 37.4 bits (85), Expect = 0.028 Identities = 32/122 (26%), Positives = 46/122 (37%) Frame = +1 Query: 115 RGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGH 294 RGH+ V + D ++ S++ D ++ +WDLT G GH Sbjct: 144 RGHSQAVRCLRFSPDGK-WLASAADDHTVKLWDLTA------------GKMMSEFPGHTG 190 Query: 295 FVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSAS 474 V V + SGS D +R WDL G V SV F+ D + S Sbjct: 191 PVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDGCCLYSGC 250 Query: 475 RD 480 +D Sbjct: 251 QD 252 Score = 34.7 bits (78), Expect = 0.18 Identities = 19/78 (24%), Positives = 35/78 (44%), Gaps = 1/78 (1%) Frame = +1 Query: 271 RRLTGHGHFVQDVVLS-SDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSI 447 + + H V +VL + G+ +G D + LW ++ GH V SV + Sbjct: 14 QEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNT 73 Query: 448 DNRQIVSASRDRTIKLWN 501 IV+ S+ +I++W+ Sbjct: 74 PEELIVAGSQSGSIRVWD 91
>WSB1_HUMAN (Q9Y6I7) WD repeat and SOCS box-containing protein 1 (WSB-1) (SOCS| box-containing WD protein SWiP-1) Length = 421 Score = 62.4 bits (150), Expect = 8e-10 Identities = 38/127 (29%), Positives = 58/127 (45%) Frame = +1 Query: 121 HNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFV 300 H +VV + D S +VS+SRDK+L VWDL + G + L GH ++V Sbjct: 169 HTEVVRDLTFAPDGSLILVSASRDKTLRVWDLKDD-----------GNMMKVLRGHQNWV 217 Query: 301 QDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRD 480 S D S + LW++ R+ GH DV++ FS D + +AS D Sbjct: 218 YSCAFSPDSSMLCSVGASKAVFLWNMDKYTMIRKLEGHHHDVVACDFSPDGALLATASYD 277 Query: 481 RTIKLWN 501 + +W+ Sbjct: 278 TRVYIWD 284 Score = 35.8 bits (81), Expect = 0.083 Identities = 33/134 (24%), Positives = 55/134 (41%), Gaps = 6/134 (4%) Frame = +1 Query: 121 HNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLT------ 282 H+DVV +P + + ++S D + +WD N D E+G F T Sbjct: 256 HHDVVACDFSP--DGALLATASYDTRVYIWDPHNG-----DILMEFGHLFPPPTPIFAGG 308 Query: 283 GHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQI 462 + +V+ V S DG S + D +R W + + V + L AFS D + Sbjct: 309 ANDRWVRSVSFSHDGLHVASLADDKMVRFWRIDEDYPVQ--VAPLSNGLCCAFSTDGSVL 366 Query: 463 VSASRDRTIKLWNT 504 + + D ++ W T Sbjct: 367 AAGTHDGSVYFWAT 380
>WDR48_MOUSE (Q8BH57) WD-repeat protein 48| Length = 676 Score = 62.4 bits (150), Expect = 8e-10 Identities = 38/130 (29%), Positives = 63/130 (48%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 +R H D V A+A D + S+ D+ + +WD+ T T+S V L+G+ Sbjct: 113 LRTHKDYVKALAYAKDKE-LVASAGLDRQIFLWDVNT---LTALTASNNTVTTSSLSGNK 168 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSA 471 + + ++ G +SGS + LR+WD T + GH +V ++ D Q +S Sbjct: 169 DSIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLHRDGTQCLSG 228 Query: 472 SRDRTIKLWN 501 S D TI+LW+ Sbjct: 229 SSDGTIRLWS 238 Score = 48.9 bits (115), Expect = 9e-06 Identities = 32/114 (28%), Positives = 53/114 (46%), Gaps = 2/114 (1%) Frame = +1 Query: 172 IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSW 351 + ++ RD + +W + Q S E+ H +V DVVL +G+ +S S Sbjct: 45 LFTAGRDSIIRIWSVNQHKQDPYIASMEH---------HTDWVNDVVLCCNGKTLISASS 95 Query: 352 DGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLW--NTL 507 D +++W+ G H+ V ++A++ D + SA DR I LW NTL Sbjct: 96 DTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDVNTL 149 Score = 48.5 bits (114), Expect = 1e-05 Identities = 39/140 (27%), Positives = 59/140 (42%) Frame = +1 Query: 70 TMAGAQESLVYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTS 249 T A + V + G+ D + ++A IVS S +K L VWD + Sbjct: 150 TALTASNNTVTTSSLSGNKDSIYSLAMN-QLGTIIVSGSTEKVLRVWDPRTCAK------ 202 Query: 250 SEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVL 429 +L GH V+ ++L DG LSGS DG +RLW L + H++ V Sbjct: 203 ------LMKLKGHTDNVKALLLHRDGTQCLSGSSDGTIRLWSLGQQRCIATYRVHDEGVW 256 Query: 430 SVAFSIDNRQIVSASRDRTI 489 ++ + + S RDR I Sbjct: 257 ALQVNDAFTHVYSGGRDRKI 276
>GBB3_TOBAC (Q40507) Guanine nucleotide-binding protein beta subunit| Length = 375 Score = 62.4 bits (150), Expect = 8e-10 Identities = 42/133 (31%), Positives = 71/133 (53%), Gaps = 2/133 (1%) Frame = +1 Query: 109 VMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 ++ GH V++ D +++SS D++ ++WD+T ++ +S +G F+ +GH Sbjct: 151 MLSGHKGYVSSCQYVPDEDTHLITSSGDQTCVLWDITTGLR-----TSVFGGEFQ--SGH 203 Query: 289 GHFVQDV-VLSSDGQFALSGSWDGELRLWDLSTGVTTRR-FVGHEKDVLSVAFSIDNRQI 462 VQ V + SS+ + +SGS D RLWD +R F GHE DV +V F D + Sbjct: 204 TADVQSVSISSSNPRLFVSGSCDTTARLWDNRVASRAQRTFYGHEGDVNTVKFFPDGNRF 263 Query: 463 VSASRDRTIKLWN 501 + S D T +L++ Sbjct: 264 GTGSEDGTCRLFD 276 Score = 45.1 bits (105), Expect = 1e-04 Identities = 53/196 (27%), Positives = 79/196 (40%), Gaps = 46/196 (23%) Frame = +1 Query: 52 RSLRHTTMAGAQESLVYAGVMRGHNDVVTAIA-TPIDNSPFIVSSSRDKSLLVWD-LTNP 225 RS T + LV +++GH V ++ TP N IVS+S+D L+VW+ LT+ Sbjct: 41 RSQGKTPVTFGPTDLVCCRILQGHTGKVYSLDWTPEKNR--IVSASQDGRLIVWNALTSQ 98 Query: 226 -------------------------------------IQATQDTSSEYGVPFRRLTGHGH 294 + + D + V R L+GH Sbjct: 99 KTHAIKLPCAWVMTCAFSPSGQSVACGGLDSVCSIYNLNSPIDKDGNHPVS-RMLSGHKG 157 Query: 295 FVQDV-VLSSDGQFALSGSWDGELRLWDLSTGVTTRRF-----VGHEKDVLSVAFSIDN- 453 +V + + ++ S D LWD++TG+ T F GH DV SV+ S N Sbjct: 158 YVSSCQYVPDEDTHLITSSGDQTCVLWDITTGLRTSVFGGEFQSGHTADVQSVSISSSNP 217 Query: 454 RQIVSASRDRTIKLWN 501 R VS S D T +LW+ Sbjct: 218 RLFVSGSCDTTARLWD 233 Score = 43.5 bits (101), Expect = 4e-04 Identities = 40/148 (27%), Positives = 58/148 (39%), Gaps = 5/148 (3%) Frame = +1 Query: 79 GAQESLVYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEY 258 G + S+ GH V +++ N VS S D + +WD +A Sbjct: 189 GLRTSVFGGEFQSGHTADVQSVSISSSNPRLFVSGSCDTTARLWDNRVASRAQ------- 241 Query: 259 GVPFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFV-----GHEKD 423 R GH V V DG +GS DG RL+D+ TG + + G Sbjct: 242 ----RTFYGHEGDVNTVKFFPDGNRFGTGSEDGTCRLFDIRTGHQLQVYYQPHGDGDIPH 297 Query: 424 VLSVAFSIDNRQIVSASRDRTIKLWNTL 507 V S+AFSI R + + +W+TL Sbjct: 298 VTSMAFSISGRLLFVGYSNGDCYVWDTL 325 Score = 29.6 bits (65), Expect = 5.9 Identities = 15/40 (37%), Positives = 23/40 (57%) Frame = +1 Query: 388 VTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNTL 507 V R GH V S+ ++ + +IVSAS+D + +WN L Sbjct: 56 VCCRILQGHTGKVYSLDWTPEKNRIVSASQDGRLIVWNAL 95
>HIRL_SCHPO (P87314) Histone transcription regulator 1 homolog| Length = 932 Score = 62.0 bits (149), Expect = 1e-09 Identities = 37/135 (27%), Positives = 61/135 (45%), Gaps = 6/135 (4%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDT------SSEYGVPFR 273 M H VT++ N ++ S S D+ +++W I T +E +R Sbjct: 70 MSTHTGTVTSVRFS-PNGQYLASGSDDRVVIIWHKEEAIPGLGSTFGSGEKHTENWRSYR 128 Query: 274 RLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDN 453 RL GH + +QD+ S D Q +S D + +W+ +T +R H+ V + F Sbjct: 129 RLLGHDNDIQDLCWSYDSQLVVSVGLDSSIIVWNGTTFERLKRIEAHQSHVKGITFDPAG 188 Query: 454 RQIVSASRDRTIKLW 498 + + S DRTIK+W Sbjct: 189 KYFATESDDRTIKVW 203 Score = 34.7 bits (78), Expect = 0.18 Identities = 28/106 (26%), Positives = 41/106 (38%), Gaps = 16/106 (15%) Frame = +1 Query: 283 GHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRR----------------FVGH 414 GH + + + DG +G DG +R+W ST R H Sbjct: 16 GHRLSIFSIHIHPDGSRIATGGLDGTIRIW--STEAINRENENENENEDLPKQLCCMSTH 73 Query: 415 EKDVLSVAFSIDNRQIVSASRDRTIKLWNTLGECKYTIGGDLGGGE 552 V SV FS + + + S S DR + +W+ E +G G GE Sbjct: 74 TGTVTSVRFSPNGQYLASGSDDRVVIIWHK-EEAIPGLGSTFGSGE 118
>YZLL_CAEEL (Q93847) Hypothetical WD-repeat protein K04G11.4| Length = 395 Score = 62.0 bits (149), Expect = 1e-09 Identities = 44/145 (30%), Positives = 66/145 (45%), Gaps = 1/145 (0%) Frame = +1 Query: 97 VYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRR 276 VY + GH + + D S IVS S DK + V+D+++ G + Sbjct: 139 VYEKTLMGHRLGINEFSWSSD-SKLIVSCSDDKLVKVFDVSS------------GRCVKT 185 Query: 277 LTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNR 456 L GH ++V + G SGS+D +R+W G T GHE V SV F+ D Sbjct: 186 LKGHTNYVFCCCFNPSGTLIASGSFDETIRIWCARNGNTIFSIPGHEDPVSSVCFNRDGA 245 Query: 457 QIVSASRDRTIKLW-NTLGECKYTI 528 + S S D +++W +T G C T+ Sbjct: 246 YLASGSYDGIVRIWDSTTGTCVKTL 270 Score = 57.8 bits (138), Expect = 2e-08 Identities = 34/131 (25%), Positives = 66/131 (50%), Gaps = 1/131 (0%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 ++GH + V + I S S D+++ +W ++ ++ + +P GH Sbjct: 186 LKGHTNYVFCCCFN-PSGTLIASGSFDETIRIW-------CARNGNTIFSIP-----GHE 232 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHE-KDVLSVAFSIDNRQIVS 468 V V + DG + SGS+DG +R+WD +TG + + E + V FS + + I++ Sbjct: 233 DPVSSVCFNRDGAYLASGSYDGIVRIWDSTTGTCVKTLIDEEHPPITHVKFSPNGKYILA 292 Query: 469 ASRDRTIKLWN 501 ++ + T+KLW+ Sbjct: 293 SNLNNTLKLWD 303 Score = 48.9 bits (115), Expect = 9e-06 Identities = 36/132 (27%), Positives = 59/132 (44%), Gaps = 4/132 (3%) Frame = +1 Query: 118 GHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHF 297 GH D V+++ D + ++ S S D + +WD T G + L H Sbjct: 230 GHEDPVSSVCFNRDGA-YLASGSYDGIVRIWDSTT------------GTCVKTLIDEEHP 276 Query: 298 -VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVA--FSI-DNRQIV 465 + V S +G++ L+ + + L+LWD + + GHE VA FS+ + IV Sbjct: 277 PITHVKFSPNGKYILASNLNNTLKLWDYQKLRVLKEYTGHENSKYCVAANFSVTGGKWIV 336 Query: 466 SASRDRTIKLWN 501 S S D + +WN Sbjct: 337 SGSEDHKVYIWN 348 Score = 43.9 bits (102), Expect = 3e-04 Identities = 24/84 (28%), Positives = 46/84 (54%), Gaps = 1/84 (1%) Frame = +1 Query: 286 HGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIV 465 H + + S DG++ SGS D +++W + V + +GH + ++S D++ IV Sbjct: 106 HKKSISGIKFSPDGRYMGSGSADCSIKIWRMDF-VYEKTLMGHRLGINEFSWSSDSKLIV 164 Query: 466 SASRDRTIKLWN-TLGECKYTIGG 534 S S D+ +K+++ + G C T+ G Sbjct: 165 SCSDDKLVKVFDVSSGRCVKTLKG 188 Score = 33.5 bits (75), Expect = 0.41 Identities = 30/120 (25%), Positives = 52/120 (43%), Gaps = 5/120 (4%) Frame = +1 Query: 160 NSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLS---SDGQ 330 N +I++S+ + +L +WD EY TGH + V + + G+ Sbjct: 286 NGKYILASNLNNTLKLWDYQK-----LRVLKEY-------TGHENSKYCVAANFSVTGGK 333 Query: 331 FALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSAS--RDRTIKLWNT 504 + +SGS D ++ +W+L T + GH V+ I SA+ D IK+W + Sbjct: 334 WIVSGSEDHKVYIWNLQTREILQTLDGHNTAVMCTDCHPGQNIIASAALEPDMRIKIWRS 393
>U3IP2_HUMAN (O43818) U3 small nucleolar RNA-interacting protein 2 (U3 small| nucleolar ribonucleoproptein-associated 55-kDa protein) (U3 snoRNP-associated 55-kDa protein) (U3-55K) Length = 475 Score = 62.0 bits (149), Expect = 1e-09 Identities = 37/131 (28%), Positives = 65/131 (49%) Frame = +1 Query: 109 VMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 V+RGH +T + D+S I S+++D S++ W + + + ++ G + GH Sbjct: 141 VLRGHQLSITCLVVTPDDSA-IFSAAKDCSIIKWSVESGRKLHVIPRAKKGAEGKP-PGH 198 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVS 468 V + +SSDG++ SG + +W+ + F GH V +AF Q+ S Sbjct: 199 SSHVLCMAISSDGKYLASGDRSKLILIWEAQSCQHLYTFTGHRDAVSGLAFRRGTHQLYS 258 Query: 469 ASRDRTIKLWN 501 S DR++K+WN Sbjct: 259 TSHDRSVKVWN 269 Score = 38.9 bits (89), Expect = 0.010 Identities = 30/142 (21%), Positives = 55/142 (38%) Frame = +1 Query: 118 GHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHF 297 GH+ V +A D ++ S R K +L+W+ Q+ Q + TGH Sbjct: 197 GHSSHVLCMAISSDGK-YLASGDRSKLILIWEA----QSCQHLYT--------FTGHRDA 243 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASR 477 V + S S D +++W+++ GH+ V ++ + + R Sbjct: 244 VSGLAFRRGTHQLYSTSHDRSVKVWNVAENSYVETLFGHQDAVAALDALSRECCVTAGGR 303 Query: 478 DRTIKLWNTLGECKYTIGGDLG 543 D T+++W E + G G Sbjct: 304 DGTVRVWKIPEESQLVFYGHQG 325 Score = 29.3 bits (64), Expect = 7.8 Identities = 29/144 (20%), Positives = 54/144 (37%), Gaps = 11/144 (7%) Frame = +1 Query: 100 YAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRL 279 Y + GH D V A+ + + + RD ++ VW + Q Sbjct: 275 YVETLFGHQDAVAALDA-LSRECCVTAGGRDGTVRVWKIPEESQLV-------------F 320 Query: 280 TGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLST-----------GVTTRRFVGHEKDV 426 GH + + L ++ + +SG+ DG + LW LS G+ + + Sbjct: 321 YGHQGSIDCIHLINE-EHMVSGADDGSVALWGLSKKRPLALQREAHGLRGEPGLEQPFWI 379 Query: 427 LSVAFSIDNRQIVSASRDRTIKLW 498 SVA ++ + + S ++LW Sbjct: 380 SSVAALLNTDLVATGSHSSCVRLW 403
>WDR31_HUMAN (Q8NA23) WD-repeat protein 31| Length = 367 Score = 62.0 bits (149), Expect = 1e-09 Identities = 39/132 (29%), Positives = 63/132 (47%) Frame = +1 Query: 115 RGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGH 294 +GH +T +A +S F S+SRD+ +++WDL Q P ++L GH Sbjct: 100 KGHEHEITKVACIPKSSQFF-SASRDRMVMMWDLHGSSQ-----------PRQQLCGHAM 147 Query: 295 FVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSAS 474 V + +S D +GS D L LWD+ TG + R V + + I+ S Sbjct: 148 VVTGLAVSPDSSQLCTGSRDNTLLLWDVVTGQSVERASVSRNVVTHLCWVPREPYILQTS 207 Query: 475 RDRTIKLWNTLG 510 D+T++LW++ G Sbjct: 208 EDKTLRLWDSRG 219 Score = 50.1 bits (118), Expect = 4e-06 Identities = 35/130 (26%), Positives = 57/130 (43%), Gaps = 1/130 (0%) Frame = +1 Query: 121 HNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFV 300 H D V+ +A NS VS +DK+++ ++ G +R GH H + Sbjct: 61 HMDTVSVVAAL--NSDLCVSGGKDKTVVAYNWKT------------GNVVKRFKGHEHEI 106 Query: 301 QDVVLSSDGQFALSGSWDGELRLWDL-STGVTTRRFVGHEKDVLSVAFSIDNRQIVSASR 477 V S S D + +WDL + ++ GH V +A S D+ Q+ + SR Sbjct: 107 TKVACIPKSSQFFSASRDRMVMMWDLHGSSQPRQQLCGHAMVVTGLAVSPDSSQLCTGSR 166 Query: 478 DRTIKLWNTL 507 D T+ LW+ + Sbjct: 167 DNTLLLWDVV 176 Score = 45.4 bits (106), Expect = 1e-04 Identities = 23/68 (33%), Positives = 36/68 (52%) Frame = +1 Query: 307 VVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRT 486 VV + + +SG D + ++ TG +RF GHE ++ VA + Q SASRDR Sbjct: 67 VVAALNSDLCVSGGKDKTVVAYNWKTGNVVKRFKGHEHEITKVACIPKSSQFFSASRDRM 126 Query: 487 IKLWNTLG 510 + +W+ G Sbjct: 127 VMMWDLHG 134
>KTNB1_BRARE (Q7ZUV2) Katanin p80 WD40-containing subunit B1 homolog| Length = 694 Score = 61.6 bits (148), Expect = 1e-09 Identities = 40/132 (30%), Positives = 60/132 (45%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 + GH V I + +V+ S SL +WDL E R L GH Sbjct: 59 LTGHTSAVGCIQFN-SSEERVVAGSLSGSLRLWDL------------EAAKILRTLMGHK 105 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSA 471 + + G++ SGS D ++LWD+ R+ GH + V +AFS D + + SA Sbjct: 106 ASISSLDFHPMGEYLASGSVDSNIKLWDVRRKGCVFRYKGHTQAVRCLAFSPDGKWLASA 165 Query: 472 SRDRTIKLWNTL 507 S D T+KLW+ + Sbjct: 166 SDDSTVKLWDLI 177 Score = 57.4 bits (137), Expect = 3e-08 Identities = 35/111 (31%), Positives = 51/111 (45%) Frame = +1 Query: 169 FIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGS 348 ++ S S D ++ +WD+ G FR GH V+ + S DG++ S S Sbjct: 119 YLASGSVDSNIKLWDVRRK-----------GCVFR-YKGHTQAVRCLAFSPDGKWLASAS 166 Query: 349 WDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN 501 D ++LWDL G F H V V F + + S S DRT+KLW+ Sbjct: 167 DDSTVKLWDLIAGKMITEFTSHTSAVNVVQFHPNEYLLASGSADRTVKLWD 217 Score = 37.0 bits (84), Expect = 0.037 Identities = 34/128 (26%), Positives = 53/128 (41%) Frame = +1 Query: 115 RGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGH 294 +GH V +A D ++ S+S D ++ +WDL T+ TS H Sbjct: 144 KGHTQAVRCLAFSPDGK-WLASASDDSTVKLWDLIAGKMITEFTS------------HTS 190 Query: 295 FVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSAS 474 V V + SGS D ++LWDL G V SV F+ D + S S Sbjct: 191 AVNVVQFHPNEYLLASGSADRTVKLWDLEKFNMIGSSEGETGVVRSVLFNPDGSCLYSGS 250 Query: 475 RDRTIKLW 498 + T++++ Sbjct: 251 -ENTLRVY 257 Score = 34.7 bits (78), Expect = 0.18 Identities = 18/78 (23%), Positives = 35/78 (44%), Gaps = 1/78 (1%) Frame = +1 Query: 271 RRLTGHGHFVQDVVLS-SDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSI 447 + + H V +VL S G+ +G D + +W +S GH V + F+ Sbjct: 14 QEIVAHSSNVSSLVLGKSSGRLLATGGEDCRVNIWAVSKPNCIMSLTGHTSAVGCIQFNS 73 Query: 448 DNRQIVSASRDRTIKLWN 501 ++V+ S +++LW+ Sbjct: 74 SEERVVAGSLSGSLRLWD 91
>STRN3_HUMAN (Q13033) Striatin-3 (Cell-cycle autoantigen SG2NA) (S/G2 antigen)| Length = 797 Score = 61.6 bits (148), Expect = 1e-09 Identities = 45/156 (28%), Positives = 74/156 (47%), Gaps = 14/156 (8%) Frame = +1 Query: 112 MRGHNDVVTAIAT-PIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 +R H D V A+A P++ P +V++S D +L +W+L + A + S + P H Sbjct: 476 LRSHFDGVRALAFHPVE--PVLVTASEDHTLKLWNLQKTVPAKKSASLDVE-PIYTFRAH 532 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDLST-----------GVTTRRFVGHEKDVLSV 435 V + +SS+G+ SG D ++ W++ + V VGH V + Sbjct: 533 IGPVLSLAISSNGEQCFSGGIDATIQWWNMPSPSVDPYDTYEPNVLAGTLVGHTDAVWGL 592 Query: 436 AFSIDNRQIVSASRDRTIKLWNTLGE--CKYTIGGD 537 A+S Q++S S D T++LWN + C T GD Sbjct: 593 AYSGIKNQLLSCSADGTVRLWNPQEKLPCICTYNGD 628 Score = 38.5 bits (88), Expect = 0.013 Identities = 27/133 (20%), Positives = 54/133 (40%), Gaps = 4/133 (3%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 ++ +N + ++ P P +++ D+ + +D ++ G + H Sbjct: 678 LQSNNHINRVVSHP--TLPVTITAHEDRHIKFFD------------NKTGKMIHSMVAHL 723 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEK----DVLSVAFSIDNRQ 459 V + + +G + +SGS D +RLW+L + + H K + VAF Sbjct: 724 DAVTSLAVDPNGIYLMSGSHDCSIRLWNLDSKTCVQEITAHRKKLDESIYDVAFHSSKAY 783 Query: 460 IVSASRDRTIKLW 498 I SA D K++ Sbjct: 784 IASAGADALAKVF 796 Score = 32.0 bits (71), Expect = 1.2 Identities = 16/50 (32%), Positives = 25/50 (50%) Frame = +1 Query: 352 DGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN 501 D ++ +D TG V H V S+A + ++S S D +I+LWN Sbjct: 702 DRHIKFFDNKTGKMIHSMVAHLDAVTSLAVDPNGIYLMSGSHDCSIRLWN 751
>TAF5_SCHPO (O13282) Transcription initiation factor TFIID subunit 5| (Transcription initiation factor TFIID 72 kDa subunit) (TAFII-72) Length = 643 Score = 61.2 bits (147), Expect = 2e-09 Identities = 37/131 (28%), Positives = 61/131 (46%) Frame = +1 Query: 109 VMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 V GH V + T NS ++++ S DK+ +WD+ G R GH Sbjct: 458 VFAGHLSDVDCV-TFHPNSAYVLTGSSDKTCRLWDVHR------------GHSVRVFNGH 504 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVS 468 V V ++ DG S +G + LWD+ TG + GH ++ S++FS ++ +VS Sbjct: 505 TQPVTAVAIAPDGHTMASADSEGLIHLWDIGTGRRIKTMRGHRGNIYSLSFSRESTVLVS 564 Query: 469 ASRDRTIKLWN 501 D T++ W+ Sbjct: 565 GGSDCTVRAWD 575 Score = 54.3 bits (129), Expect = 2e-07 Identities = 31/91 (34%), Positives = 44/91 (48%) Frame = +1 Query: 229 QATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFV 408 Q Q S ++ P R GH V V + + L+GS D RLWD+ G + R F Sbjct: 443 QTAQLWSCDHIYPLRVFAGHLSDVDCVTFHPNSAYVLTGSSDKTCRLWDVHRGHSVRVFN 502 Query: 409 GHEKDVLSVAFSIDNRQIVSASRDRTIKLWN 501 GH + V +VA + D + SA + I LW+ Sbjct: 503 GHTQPVTAVAIAPDGHTMASADSEGLIHLWD 533 Score = 48.5 bits (114), Expect = 1e-05 Identities = 32/115 (27%), Positives = 48/115 (41%), Gaps = 1/115 (0%) Frame = +1 Query: 160 NSPFIVSSSRDKSLLVWDL-TNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFA 336 +S I ++ + +W + + + TS E RL H V S D ++ Sbjct: 335 DSTMIACGFQESYIRLWSIKADKKSLPKSTSVEDSDGSVRLLSHSGPVYGTTFSPDNKYL 394 Query: 337 LSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN 501 LS S D RLW + T + GH V VAF +AS D+T +LW+ Sbjct: 395 LSCSEDASARLWSVDTKTALVAYKGHTGPVWDVAFGPFGHYFATASHDQTAQLWS 449 Score = 45.1 bits (105), Expect = 1e-04 Identities = 31/114 (27%), Positives = 52/114 (45%) Frame = +1 Query: 160 NSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFAL 339 ++ +++S S D S +W + DT + V ++ GH V DV G + Sbjct: 390 DNKYLLSCSEDASARLWSV--------DTKTAL-VAYK---GHTGPVWDVAFGPFGHYFA 437 Query: 340 SGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN 501 + S D +LW R F GH DV V F ++ +++ S D+T +LW+ Sbjct: 438 TASHDQTAQLWSCDHIYPLRVFAGHLSDVDCVTFHPNSAYVLTGSSDKTCRLWD 491 Score = 30.0 bits (66), Expect = 4.5 Identities = 21/90 (23%), Positives = 36/90 (40%) Frame = +1 Query: 109 VMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 V GH VTA+A D + S+ + + +WD+ G + + GH Sbjct: 500 VFNGHTQPVTAVAIAPDGHT-MASADSEGLIHLWDIGT------------GRRIKTMRGH 546 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDL 378 + + S + +SG D +R WD+ Sbjct: 547 RGNIYSLSFSRESTVLVSGGSDCTVRAWDV 576
>MORG1_RAT (Q5BLX8) Mitogen-activated protein kinase organizer 1 (MAPK| organizer 1) Length = 315 Score = 61.2 bits (147), Expect = 2e-09 Identities = 38/123 (30%), Positives = 62/123 (50%) Frame = +1 Query: 133 VTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVV 312 V A+ +D + + ++ DK+L +W NP++ T R +GHG+ V D Sbjct: 28 VRAVRFNVDGN-YCLTCGSDKTLKLW---NPLRGTL---------LRTYSGHGYEVLDAA 74 Query: 313 LSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIK 492 S D SG D + LWD++TG R+F GH V +V F+ + I+S S D +++ Sbjct: 75 GSFDNSHLCSGGGDKTVVLWDVATGQVVRKFRGHAGKVNTVQFNEEATVILSGSIDSSVR 134 Query: 493 LWN 501 W+ Sbjct: 135 CWD 137 Score = 41.2 bits (95), Expect = 0.002 Identities = 42/161 (26%), Positives = 60/161 (37%), Gaps = 32/161 (19%) Frame = +1 Query: 115 RGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTN----PIQATQDTSSEYGVPFRRLT 282 RGH V + + + I+S S D S+ WD + P+Q + G+ +++ Sbjct: 106 RGHAGKVNTVQFN-EEATVILSGSIDSSVRCWDCRSRKPEPVQTLDEARD--GISSVKVS 162 Query: 283 GH------------------GHFVQDVV--------LSSDGQFALSGSWDGELRLWDLST 384 H G D V S DGQ L S D LRL D T Sbjct: 163 DHEILAGSVDGRVRRYDLRMGQVTSDYVGSPITCTCFSRDGQCTLISSLDSTLRLLDKDT 222 Query: 385 GVTTRRFVGH--EKDVLSVAFSIDNRQIVSASRDRTIKLWN 501 G +VGH +K L S + +VS S D + W+ Sbjct: 223 GELLGEYVGHKNQKYKLDCCLSERDTHVVSCSEDGKVFFWD 263 Score = 29.6 bits (65), Expect = 5.9 Identities = 11/28 (39%), Positives = 18/28 (64%) Frame = +1 Query: 424 VLSVAFSIDNRQIVSASRDRTIKLWNTL 507 V +V F++D ++ D+T+KLWN L Sbjct: 28 VRAVRFNVDGNYCLTCGSDKTLKLWNPL 55
>MORG1_MOUSE (Q9DAJ4) Mitogen-activated protein kinase organizer 1 (MAPK| organizer 1) Length = 315 Score = 61.2 bits (147), Expect = 2e-09 Identities = 38/123 (30%), Positives = 62/123 (50%) Frame = +1 Query: 133 VTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVV 312 V A+ +D + + ++ DK+L +W NP++ T R +GHG+ V D Sbjct: 28 VRAVRFNVDGN-YCLTCGSDKTLKLW---NPLRGTL---------LRTYSGHGYEVLDAA 74 Query: 313 LSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIK 492 S D SG D + LWD++TG R+F GH V +V F+ + I+S S D +++ Sbjct: 75 GSFDNSHLCSGGGDKTVVLWDVATGQVVRKFRGHAGKVNTVQFNEEATVILSGSIDSSVR 134 Query: 493 LWN 501 W+ Sbjct: 135 CWD 137 Score = 39.3 bits (90), Expect = 0.007 Identities = 41/161 (25%), Positives = 59/161 (36%), Gaps = 32/161 (19%) Frame = +1 Query: 115 RGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTN----PIQATQDTSSEYGVPFRRLT 282 RGH V + + + I+S S D S+ WD + P+Q + G+ +++ Sbjct: 106 RGHAGKVNTVQFN-EEATVILSGSIDSSVRCWDCRSRKPEPVQTLDEARD--GISSVKVS 162 Query: 283 GH------------------GHFVQDVV--------LSSDGQFALSGSWDGELRLWDLST 384 H G D V S DGQ L S D LRL D T Sbjct: 163 DHEILAGSVDGRVRRYDLRMGQVSSDYVGSPITCTCFSRDGQCTLISSLDSTLRLLDKDT 222 Query: 385 GVTTRRFVGHEKD--VLSVAFSIDNRQIVSASRDRTIKLWN 501 G +VGH+ L S + +VS S D + W+ Sbjct: 223 GELLGEYVGHKNQQYKLDCCLSERDTHVVSCSEDGKVFFWD 263 Score = 29.6 bits (65), Expect = 5.9 Identities = 11/28 (39%), Positives = 18/28 (64%) Frame = +1 Query: 424 VLSVAFSIDNRQIVSASRDRTIKLWNTL 507 V +V F++D ++ D+T+KLWN L Sbjct: 28 VRAVRFNVDGNYCLTCGSDKTLKLWNPL 55
>KTNB1_STRPU (O61585) Katanin p80 WD40-containing subunit B1 (Katanin p80| subunit B1) (p80 katanin) Length = 690 Score = 61.2 bits (147), Expect = 2e-09 Identities = 41/140 (29%), Positives = 67/140 (47%), Gaps = 7/140 (5%) Frame = +1 Query: 148 TPIDNSPF------IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDV 309 +P+D+ F +V+ S+ ++ ++DL E R LTGH + ++ + Sbjct: 60 SPVDSVKFNSSEELVVAGSQSGTMKIYDL------------EPAKIVRTLTGHRNSIRCM 107 Query: 310 VLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTI 489 G+F SGS D ++LWD+ + GH V + FS D + +V+AS D TI Sbjct: 108 DFHPFGEFVASGSTDTNVKLWDVRRKGCIYTYKGHSDQVNMIKFSPDGKWLVTASEDTTI 167 Query: 490 KLWN-TLGECKYTIGGDLGG 546 KLW+ T+G+ GG Sbjct: 168 KLWDLTMGKLFQEFKNHTGG 187 Score = 52.0 bits (123), Expect = 1e-06 Identities = 30/111 (27%), Positives = 51/111 (45%) Frame = +1 Query: 169 FIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGS 348 F+ S S D ++ +WD+ G + GH V + S DG++ ++ S Sbjct: 115 FVASGSTDTNVKLWDVRRK-----------GCIYT-YKGHSDQVNMIKFSPDGKWLVTAS 162 Query: 349 WDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN 501 D ++LWDL+ G + F H V + F + + S S DRT++ W+ Sbjct: 163 EDTTIKLWDLTMGKLFQEFKNHTGGVTGIEFHPNEFLLASGSSDRTVQFWD 213 Score = 47.0 bits (110), Expect = 4e-05 Identities = 25/87 (28%), Positives = 40/87 (45%), Gaps = 1/87 (1%) Frame = +1 Query: 277 LTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNR 456 L+GH V V +S + ++GS G ++++DL R GH + + F Sbjct: 55 LSGHTSPVDSVKFNSSEELVVAGSQSGTMKIYDLEPAKIVRTLTGHRNSIRCMDFHPFGE 114 Query: 457 QIVSASRDRTIKLWNTLGE-CKYTIGG 534 + S S D +KLW+ + C YT G Sbjct: 115 FVASGSTDTNVKLWDVRRKGCIYTYKG 141 Score = 39.7 bits (91), Expect = 0.006 Identities = 31/122 (25%), Positives = 50/122 (40%) Frame = +1 Query: 115 RGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGH 294 +GH+D V I D ++V++S D ++ +WDLT G F+ H Sbjct: 140 KGHSDQVNMIKFSPDGK-WLVTASEDTTIKLWDLT------------MGKLFQEFKNHTG 186 Query: 295 FVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSAS 474 V + + SGS D ++ WDL T V S++F D + +S Sbjct: 187 GVTGIEFHPNEFLLASGSSDRTVQFWDLETFQLVSSTSPGASAVRSISFHPDGSYLFCSS 246 Query: 475 RD 480 +D Sbjct: 247 QD 248 Score = 30.4 bits (67), Expect = 3.5 Identities = 19/78 (24%), Positives = 35/78 (44%), Gaps = 1/78 (1%) Frame = +1 Query: 271 RRLTGHGHFVQDVVLSS-DGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSI 447 + L H V + L G+ ++G D ++ LW + GH V SV F+ Sbjct: 10 QELVAHSSNVNCLALGPMSGRVMVTGGEDKKVNLWAVGKQNCIISLSGHTSPVDSVKFNS 69 Query: 448 DNRQIVSASRDRTIKLWN 501 +V+ S+ T+K+++ Sbjct: 70 SEELVVAGSQSGTMKIYD 87
>STRN_RAT (P70483) Striatin| Length = 780 Score = 61.2 bits (147), Expect = 2e-09 Identities = 42/143 (29%), Positives = 71/143 (49%), Gaps = 12/143 (8%) Frame = +1 Query: 112 MRGHNDVVTAIAT-PIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 +R H D + A+A PI+ P ++++S D +L +W+L A + TS + P H Sbjct: 459 LRSHFDGIRALAFHPIE--PVLITASEDHTLKMWNLQKTAPAKKSTSLDVE-PIYTFRAH 515 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDLST-----------GVTTRRFVGHEKDVLSV 435 V VV+SS+G+ SG DG ++ W + V +GH V + Sbjct: 516 KGPVLCVVMSSNGEQCYSGGTDGLIQSWSTTNPNVDPYDSYDPSVLRGPLLGHTDAVWGL 575 Query: 436 AFSIDNRQIVSASRDRTIKLWNT 504 A+S +++++S S D T++LW T Sbjct: 576 AYSAAHQRLLSCSADGTLRLWTT 598 Score = 38.9 bits (89), Expect = 0.010 Identities = 22/78 (28%), Positives = 36/78 (46%), Gaps = 4/78 (5%) Frame = +1 Query: 277 LTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGH----EKDVLSVAFS 444 + H V + + +G + +SGS D +RLW+L + + F H E+ + VAF Sbjct: 702 MVAHLEAVTSLAVDPNGLYLMSGSHDCSIRLWNLESKTCIQEFTAHRKKFEESIHDVAFH 761 Query: 445 IDNRQIVSASRDRTIKLW 498 I SA D K++ Sbjct: 762 PSKCYIASAGADALAKVF 779 Score = 33.9 bits (76), Expect = 0.31 Identities = 16/50 (32%), Positives = 27/50 (54%) Frame = +1 Query: 352 DGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN 501 D ++ +D +TG V H + V S+A + ++S S D +I+LWN Sbjct: 685 DRHIKFYDNNTGKLIHSMVAHLEAVTSLAVDPNGLYLMSGSHDCSIRLWN 734
>WD51B_MOUSE (Q8BHD1) WD-repeat protein 51B| Length = 476 Score = 60.8 bits (146), Expect = 2e-09 Identities = 43/130 (33%), Positives = 65/130 (50%), Gaps = 1/130 (0%) Frame = +1 Query: 118 GHNDVVTAIA-TPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGH 294 GH DVVT++ +P N + S+SRD+++ +W L + SSE+ H Sbjct: 58 GHKDVVTSLQFSPQGN--LLASASRDRTVRLWVLDR-----KGKSSEF-------KAHTA 103 Query: 295 FVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSAS 474 V+ V S+DGQ ++ S D +++W + H V FS D R IVS S Sbjct: 104 PVRSVDFSADGQLLVTASEDKSIKVWSMFRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCS 163 Query: 475 RDRTIKLWNT 504 D+TIK+W+T Sbjct: 164 EDKTIKIWDT 173 Score = 59.7 bits (143), Expect = 5e-09 Identities = 43/143 (30%), Positives = 62/143 (43%) Frame = +1 Query: 73 MAGAQESLVYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSS 252 MA E + +GH +T+ A N I ++S D L++W L +A Sbjct: 1 MASGLEDPILERSFKGHKAAITS-ADFSPNCKQIATASWDTFLMLWSLKPHARAY----- 54 Query: 253 EYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLS 432 R GH V + S G S S D +RLW L + F H V S Sbjct: 55 -------RYVGHKDVVTSLQFSPQGNLLASASRDRTVRLWVLDRKGKSSEFKAHTAPVRS 107 Query: 433 VAFSIDNRQIVSASRDRTIKLWN 501 V FS D + +V+AS D++IK+W+ Sbjct: 108 VDFSADGQLLVTASEDKSIKVWS 130 Score = 39.3 bits (90), Expect = 0.007 Identities = 37/142 (26%), Positives = 55/142 (38%), Gaps = 31/142 (21%) Frame = +1 Query: 172 IVSSSRDKSLLVWDLTNPIQATQDTSSEYG----VPFR------RLTGHGHFVQ--DVVL 315 IVS S DK++ +WD TN Q + S G V F G H V+ D+ + Sbjct: 159 IVSCSEDKTIKIWDTTNK-QCVNNFSDSVGFANFVDFNPNGTCIASAGSDHAVKIWDIRM 217 Query: 316 SSD-------------------GQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVA 438 + G ++ S DG +++ DL G GH V +V+ Sbjct: 218 NKLLQHYQVHSCGVNCLSFHPLGNSLVTASSDGTVKMLDLIEGRLIYTLQGHTGPVFTVS 277 Query: 439 FSIDNRQIVSASRDRTIKLWNT 504 FS D + S D + +W T Sbjct: 278 FSKDGELLTSGGADAQVLIWRT 299
>GBB1_CAEEL (P17343) Guanine nucleotide-binding protein beta subunit 1| Length = 340 Score = 60.8 bits (146), Expect = 2e-09 Identities = 39/128 (30%), Positives = 59/128 (46%) Frame = +1 Query: 118 GHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHF 297 GH ++ DN IV+SS D + +WD+ Q T TGH Sbjct: 141 GHTGYLSCCRFLDDNQ--IVTSSGDMTCALWDIETGQQCTA------------FTGHTGD 186 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASR 477 V + LS D + +SG+ D +LWD+ G+ + F GHE D+ +VAF + S Sbjct: 187 VMSLSLSPDFRTFISGACDASAKLWDIRDGMCKQTFPGHESDINAVAFFPSGNAFATGSD 246 Query: 478 DRTIKLWN 501 D T +L++ Sbjct: 247 DATCRLFD 254 Score = 32.7 bits (73), Expect = 0.70 Identities = 16/68 (23%), Positives = 27/68 (39%) Frame = +1 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASR 477 + V S G+ +G D +WD GH+ V + + D + + S Sbjct: 273 ITSVAFSKSGRLLFAGYDDFNCNVWDSMRQERAGVLAGHDNRVSCLGVTEDGMAVCTGSW 332 Query: 478 DRTIKLWN 501 D +K+WN Sbjct: 333 DSFLKIWN 340 Score = 31.6 bits (70), Expect = 1.6 Identities = 12/33 (36%), Positives = 20/33 (60%) Frame = +1 Query: 277 LTGHGHFVQDVVLSSDGQFALSGSWDGELRLWD 375 L GH + V + ++ DG +GSWD L++W+ Sbjct: 308 LAGHDNRVSCLGVTEDGMAVCTGSWDSFLKIWN 340
>GBB1_CAEBR (Q61ZF6) Guanine nucleotide-binding protein beta subunit 1| Length = 340 Score = 60.8 bits (146), Expect = 2e-09 Identities = 39/128 (30%), Positives = 59/128 (46%) Frame = +1 Query: 118 GHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHF 297 GH ++ DN IV+SS D + +WD+ Q T TGH Sbjct: 141 GHTGYLSCCRFLDDNQ--IVTSSGDMTCALWDIETGQQCTA------------FTGHTGD 186 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASR 477 V + LS D + +SG+ D +LWD+ G+ + F GHE D+ +VAF + S Sbjct: 187 VMSLSLSPDFRTFISGACDASAKLWDIRDGMCKQTFPGHESDINAVAFFPSGNAFATGSD 246 Query: 478 DRTIKLWN 501 D T +L++ Sbjct: 247 DATCRLFD 254 Score = 32.7 bits (73), Expect = 0.70 Identities = 16/68 (23%), Positives = 27/68 (39%) Frame = +1 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASR 477 + V S G+ +G D +WD GH+ V + + D + + S Sbjct: 273 ITSVAFSKSGRLLFAGYDDFNCNVWDSMRQERAGVLAGHDNRVSCLGVTEDGMAVCTGSW 332 Query: 478 DRTIKLWN 501 D +K+WN Sbjct: 333 DSFLKIWN 340 Score = 31.6 bits (70), Expect = 1.6 Identities = 12/33 (36%), Positives = 20/33 (60%) Frame = +1 Query: 277 LTGHGHFVQDVVLSSDGQFALSGSWDGELRLWD 375 L GH + V + ++ DG +GSWD L++W+ Sbjct: 308 LAGHDNRVSCLGVTEDGMAVCTGSWDSFLKIWN 340
>STRN3_MOUSE (Q9ERG2) Striatin-3 (Cell-cycle autoantigen SG2NA) (S/G2 antigen)| Length = 796 Score = 60.5 bits (145), Expect = 3e-09 Identities = 45/156 (28%), Positives = 73/156 (46%), Gaps = 14/156 (8%) Frame = +1 Query: 112 MRGHNDVVTAIAT-PIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 +R H D V A+A P++ P +V++S D +L +W+L + A + S + P H Sbjct: 475 LRSHFDGVRALAFHPVE--PVLVTASEDHTLKLWNLQKTVPAKKSASLDVE-PIYTFRAH 531 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDL-----------STGVTTRRFVGHEKDVLSV 435 V + +SS+G+ SG D ++ W++ + V V H V + Sbjct: 532 IGPVLSLAISSNGEQCFSGGIDATIQWWNMPSPNVDPYDTYESNVLAGTLVAHTDAVWGL 591 Query: 436 AFSIDNRQIVSASRDRTIKLWNTLGE--CKYTIGGD 537 A+S Q++S S D TI+LWN + C T GD Sbjct: 592 AYSGIKNQLLSCSADGTIRLWNPQEKLPCVCTYNGD 627 Score = 37.7 bits (86), Expect = 0.022 Identities = 22/84 (26%), Positives = 35/84 (41%), Gaps = 4/84 (4%) Frame = +1 Query: 259 GVPFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEK----DV 426 G + H V + + +G + +SGS D +RLW+L + + H K + Sbjct: 712 GKMIHSMVAHLDAVTSLAVDPNGIYLMSGSHDCSIRLWNLDSKTCVQEITAHRKKLDESI 771 Query: 427 LSVAFSIDNRQIVSASRDRTIKLW 498 VAF I SA D K++ Sbjct: 772 YDVAFHPSKAYIASAGADALAKVF 795 Score = 34.3 bits (77), Expect = 0.24 Identities = 45/180 (25%), Positives = 67/180 (37%), Gaps = 42/180 (23%) Frame = +1 Query: 88 ESLVYAGVMRGHNDVVTAIA-TPIDNSPFIVSSSRDKSLLVWDLTN--PIQATQDTSSEY 258 ES V AG + H D V +A + I N ++S S D ++ +W+ P T + E+ Sbjct: 573 ESNVLAGTLVAHTDAVWGLAYSGIKNQ--LLSCSADGTIRLWNPQEKLPCVCTYNGDKEH 630 Query: 259 GVPFR-RLTG--HGHFVQD-----------------VVLSSDGQFALSGS---------- 348 G+P G H V V+LSS L S Sbjct: 631 GIPTSVDFIGCDPAHMVTSFNTGSAVIYDLETSQSLVMLSSQVDSGLQSSNHINRVVSHP 690 Query: 349 ---------WDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN 501 D ++ +D TG V H V S+A + ++S S D +I+LWN Sbjct: 691 TLPVTITAHEDRHIKFFDNKTGKMIHSMVAHLDAVTSLAVDPNGIYLMSGSHDCSIRLWN 750
>WD51B_PONPY (Q5RD06) WD-repeat protein 51B| Length = 451 Score = 60.5 bits (145), Expect = 3e-09 Identities = 43/130 (33%), Positives = 64/130 (49%), Gaps = 1/130 (0%) Frame = +1 Query: 118 GHNDVVTAIA-TPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGH 294 GH DVVT++ +P N + S+SRD+++ +W I + SE+ H Sbjct: 58 GHKDVVTSVQFSPHGN--LLASASRDRTVRLW-----IPDKRGKFSEF-------KAHTA 103 Query: 295 FVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSAS 474 V+ V S+DGQF + S D +++W + H V FS D R IVS S Sbjct: 104 PVRSVDFSADGQFLATASEDKSIKVWSMYRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCS 163 Query: 475 RDRTIKLWNT 504 D+TIK+W+T Sbjct: 164 EDKTIKIWDT 173 Score = 59.7 bits (143), Expect = 5e-09 Identities = 32/85 (37%), Positives = 46/85 (54%) Frame = +1 Query: 244 TSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKD 423 +++E V R GH + + LS +G+ + SWD L LW+ R+VGH+ Sbjct: 3 SATEDPVLERYFKGHKAAITSLDLSPNGKQLATASWDTFLMLWNFKPHARAYRYVGHKDV 62 Query: 424 VLSVAFSIDNRQIVSASRDRTIKLW 498 V SV FS + SASRDRT++LW Sbjct: 63 VTSVQFSPHGNLLASASRDRTVRLW 87 Score = 38.5 bits (88), Expect = 0.013 Identities = 33/142 (23%), Positives = 47/142 (33%), Gaps = 31/142 (21%) Frame = +1 Query: 172 IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVP---------------------------- 267 IVS S DK++ +WD TN Q + S G Sbjct: 159 IVSCSEDKTIKIWDTTNK-QCVNNFSDSVGFANFVDFNPSGTCIASAGSDQTVKVWDVRV 217 Query: 268 ---FRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVA 438 + H V + + ++ S DG L++ DL G GH V +V+ Sbjct: 218 NKLLQHYQVHSGGVNCISFHPSDNYLVTASSDGTLKILDLLEGRLIYTLQGHTGPVFTVS 277 Query: 439 FSIDNRQIVSASRDRTIKLWNT 504 FS S D + LW T Sbjct: 278 FSKGGELFASGGADTQVLLWRT 299 Score = 30.8 bits (68), Expect = 2.7 Identities = 14/38 (36%), Positives = 22/38 (57%) Frame = +1 Query: 388 VTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN 501 V R F GH+ + S+ S + +Q+ +AS D + LWN Sbjct: 9 VLERYFKGHKAAITSLDLSPNGKQLATASWDTFLMLWN 46
>GBB1_CRIGR (Q6TMK6) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 339 Score = 60.5 bits (145), Expect = 3e-09 Identities = 36/130 (27%), Positives = 60/130 (46%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 + GH ++ DN IV+SS D + +WD+ Q T TGH Sbjct: 138 LAGHTGYLSCCRFLNDNQ--IVTSSEDTTCALWDIETGQQTTT------------FTGHT 183 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSA 471 V + L+ D + +SG+ D +LWD+ G+ + F GHE D+ ++ F + + Sbjct: 184 GDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATG 243 Query: 472 SRDRTIKLWN 501 S D T +L++ Sbjct: 244 SDDATCRLFD 253 Score = 34.3 bits (77), Expect = 0.24 Identities = 17/68 (25%), Positives = 28/68 (41%) Frame = +1 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASR 477 + V S G+ L+G D +WD GH+ V + + D + + S Sbjct: 272 ITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSW 331 Query: 478 DRTIKLWN 501 D +K+WN Sbjct: 332 DSFLKIWN 339 Score = 31.6 bits (70), Expect = 1.6 Identities = 12/33 (36%), Positives = 20/33 (60%) Frame = +1 Query: 277 LTGHGHFVQDVVLSSDGQFALSGSWDGELRLWD 375 L GH + V + ++ DG +GSWD L++W+ Sbjct: 307 LAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 339
>TAF5_DROME (P49846) Transcription initiation factor TFIID subunit 5| (Transcription initiation factor TFIID 85 kDa subunit) (p85) (TAFII-80) Length = 704 Score = 60.5 bits (145), Expect = 3e-09 Identities = 32/114 (28%), Positives = 54/114 (47%) Frame = +1 Query: 160 NSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFAL 339 NS ++ + S D+++ +WD + G R +TGH V + S+ G++ Sbjct: 545 NSNYVATGSSDRTVRLWD------------NMTGQSVRLMTGHKGSVSSLAFSACGRYLA 592 Query: 340 SGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN 501 SGS D + +WDLS G + H V ++ FS D + +A D + LW+ Sbjct: 593 SGSVDHNIIIWDLSNGSLVTTLLRHTSTVTTITFSRDGTVLAAAGLDNNLTLWD 646 Score = 54.7 bits (130), Expect = 2e-07 Identities = 34/111 (30%), Positives = 50/111 (45%) Frame = +1 Query: 169 FIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGS 348 + VS S DK+ +W +++ R GH V V + + +GS Sbjct: 506 YFVSCSYDKTARLW------------ATDSNQALRVFVGHLSDVDCVQFHPNSNYVATGS 553 Query: 349 WDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN 501 D +RLWD TG + R GH+ V S+AFS R + S S D I +W+ Sbjct: 554 SDRTVRLWDNMTGQSVRLMTGHKGSVSSLAFSACGRYLASGSVDHNIIIWD 604 Score = 54.7 bits (130), Expect = 2e-07 Identities = 34/112 (30%), Positives = 55/112 (49%) Frame = +1 Query: 172 IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSW 351 ++S S D ++ +W L + V +R GH + V DV + G + +S S+ Sbjct: 465 LLSCSEDSTIRLWSLL---------TWSCVVTYR---GHVYPVWDVRFAPHGYYFVSCSY 512 Query: 352 DGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNTL 507 D RLW + R FVGH DV V F ++ + + S DRT++LW+ + Sbjct: 513 DKTARLWATDSNQALRVFVGHLSDVDCVQFHPNSNYVATGSSDRTVRLWDNM 564 Score = 48.5 bits (114), Expect = 1e-05 Identities = 43/157 (27%), Positives = 60/157 (38%), Gaps = 19/157 (12%) Frame = +1 Query: 91 SLVYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNP-IQATQDTSS----- 252 S V+ V+ H V A + D+S + D S+ +W LT ++ +D S Sbjct: 367 SAVFYTVLNSHQGVTCAEIS--DDSTMLACGFGDSSVRIWSLTPAKLRTLKDADSLRELD 424 Query: 253 -------------EYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVT 393 G R L GH V + + LS S D +RLW L T Sbjct: 425 KESADINVRMLDDRSGEVTRSLMGHTGPVYRCAFAPEMNLLLSCSEDSTIRLWSLLTWSC 484 Query: 394 TRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNT 504 + GH V V F+ VS S D+T +LW T Sbjct: 485 VVTYRGHVYPVWDVRFAPHGYYFVSCSYDKTARLWAT 521
>FBXW7_DROME (Q9VZF4) F-box/WD-repeat protein 7 (F-box and WD-40 domain protein 7)| (Protein archipelago) Length = 1326 Score = 60.5 bits (145), Expect = 3e-09 Identities = 45/145 (31%), Positives = 64/145 (44%), Gaps = 1/145 (0%) Frame = +1 Query: 109 VMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 V++GH+D V N IVS S D +L VW N G R L GH Sbjct: 989 VLKGHDDHVITCLQFSGNR--IVSGSDDNTLKVWSAVN------------GKCLRTLVGH 1034 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVS 468 V +S G +SGS D L++WD+ +G GH V + ++VS Sbjct: 1035 TGGVWSSQMS--GNIIISGSTDRTLKVWDMDSGACVHTLQGHTSTVR--CMHLHGSKVVS 1090 Query: 469 ASRDRTIKLWN-TLGECKYTIGGDL 540 SRD T+++W+ G C + + G L Sbjct: 1091 GSRDATLRVWDIEQGSCLHVLVGHL 1115 Score = 57.0 bits (136), Expect = 3e-08 Identities = 44/168 (26%), Positives = 70/168 (41%), Gaps = 27/168 (16%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNP---------------------- 225 ++GH V + + +VS SRD +L VWD+ Sbjct: 1071 LQGHTSTVRCMHL---HGSKVVSGSRDATLRVWDIEQGSCLHVLVGHLAAVRCVQYDGKL 1127 Query: 226 -IQATQDTSSEYGVPFRRLTGH---GHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVT 393 + D + P R+ H GH + L DG +SGS D +R+WD+ TG Sbjct: 1128 IVSGAYDYMVKIWHPERQECLHTLQGHTNRVYSLQFDGLHVVSGSLDTSIRVWDVETGNC 1187 Query: 394 TRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN-TLGECKYTIGG 534 +GH+ L+ + +VS + D T+K+W+ T G+C T+ G Sbjct: 1188 KHTLMGHQS--LTSGMELRQNILVSGNADSTVKVWDITTGQCLQTLSG 1233 Score = 55.1 bits (131), Expect = 1e-07 Identities = 40/122 (32%), Positives = 58/122 (47%), Gaps = 1/122 (0%) Frame = +1 Query: 172 IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSW 351 I+S S D++L VWD+ + G L GH V+ + L G +SGS Sbjct: 1048 IISGSTDRTLKVWDMDS------------GACVHTLQGHTSTVRCMHLH--GSKVVSGSR 1093 Query: 352 DGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN-TLGECKYTI 528 D LR+WD+ G VGH V V + D + IVS + D +K+W+ EC +T+ Sbjct: 1094 DATLRVWDIEQGSCLHVLVGHLAAVRCVQY--DGKLIVSGAYDYMVKIWHPERQECLHTL 1151 Query: 529 GG 534 G Sbjct: 1152 QG 1153 Score = 46.6 bits (109), Expect = 5e-05 Identities = 32/111 (28%), Positives = 53/111 (47%), Gaps = 1/111 (0%) Frame = +1 Query: 172 IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSW 351 +VS S D S+ VWD+ E G L GH + L + +SG+ Sbjct: 1168 VVSGSLDTSIRVWDV------------ETGNCKHTLMGHQSLTSGMELRQN--ILVSGNA 1213 Query: 352 DGELRLWDLSTGVTTRRFVGHEKDVLSV-AFSIDNRQIVSASRDRTIKLWN 501 D +++WD++TG + G K +V ++R +V++S D T+KLW+ Sbjct: 1214 DSTVKVWDITTGQCLQTLSGPNKHHSAVTCLQFNSRFVVTSSDDGTVKLWD 1264
>WD51B_HUMAN (Q8TC44) WD-repeat protein 51B| Length = 478 Score = 60.5 bits (145), Expect = 3e-09 Identities = 43/130 (33%), Positives = 64/130 (49%), Gaps = 1/130 (0%) Frame = +1 Query: 118 GHNDVVTAIA-TPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGH 294 GH DVVT++ +P N + S+SRD+++ +W I + SE+ H Sbjct: 58 GHKDVVTSVQFSPHGN--LLASASRDRTVRLW-----IPDKRGKFSEF-------KAHTA 103 Query: 295 FVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSAS 474 V+ V S+DGQF + S D +++W + H V FS D R IVS S Sbjct: 104 PVRSVDFSADGQFLATASEDKSIKVWSMYRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCS 163 Query: 475 RDRTIKLWNT 504 D+TIK+W+T Sbjct: 164 EDKTIKIWDT 173 Score = 59.7 bits (143), Expect = 5e-09 Identities = 32/85 (37%), Positives = 46/85 (54%) Frame = +1 Query: 244 TSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKD 423 +++E V R GH + + LS +G+ + SWD L LW+ R+VGH+ Sbjct: 3 SATEDPVLERYFKGHKAAITSLDLSPNGKQLATASWDTFLMLWNFKPHARAYRYVGHKDV 62 Query: 424 VLSVAFSIDNRQIVSASRDRTIKLW 498 V SV FS + SASRDRT++LW Sbjct: 63 VTSVQFSPHGNLLASASRDRTVRLW 87 Score = 41.6 bits (96), Expect = 0.002 Identities = 34/142 (23%), Positives = 48/142 (33%), Gaps = 31/142 (21%) Frame = +1 Query: 172 IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVP---------------------------- 267 IVS S DK++ +WD TN Q + S G Sbjct: 159 IVSCSEDKTIKIWDTTNK-QCVNNFSDSVGFANFVDFNPSGTCIASAGSDQTVKVWDVRV 217 Query: 268 ---FRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVA 438 + H V + G + ++ S DG L++ DL G GH V +V+ Sbjct: 218 NKLLQHYQVHSGGVNCISFHPSGNYLITASSDGTLKILDLLEGRLIYTLQGHTGPVFTVS 277 Query: 439 FSIDNRQIVSASRDRTIKLWNT 504 FS S D + LW T Sbjct: 278 FSKGGELFASGGADTQVLLWRT 299 Score = 30.8 bits (68), Expect = 2.7 Identities = 14/38 (36%), Positives = 22/38 (57%) Frame = +1 Query: 388 VTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN 501 V R F GH+ + S+ S + +Q+ +AS D + LWN Sbjct: 9 VLERYFKGHKAAITSLDLSPNGKQLATASWDTFLMLWN 46
>WSB1_FUGRU (Q9W5Z5) WD repeat and SOCS box-containing protein 1 (WSB-1)| Length = 427 Score = 60.1 bits (144), Expect = 4e-09 Identities = 41/139 (29%), Positives = 59/139 (42%), Gaps = 4/139 (2%) Frame = +1 Query: 97 VYAGVM----RGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGV 264 VY G + H D+V + D S +VS+S DK L VWDL + G Sbjct: 162 VYTGTLLLNLMDHTDIVRDLTFAPDGSLMLVSASTDKKLRVWDLKDD-----------GN 210 Query: 265 PFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFS 444 + L GH + V S D S + LW++ R+ GH DV+S FS Sbjct: 211 MVKVLWGHPNRVYSSAFSPDSSVLCSVGASKAVLLWNMDKYTLIRKLEGHHNDVVSCEFS 270 Query: 445 IDNRQIVSASRDRTIKLWN 501 D + +AS D + +W+ Sbjct: 271 PDGALLATASYDTRVIVWD 289
>GBB2_BOVIN (P11017) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 2 (Transducin beta chain 2) (G protein beta 2 subunit) (Fragment) Length = 326 Score = 59.7 bits (143), Expect = 5e-09 Identities = 36/128 (28%), Positives = 61/128 (47%) Frame = +1 Query: 118 GHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHF 297 GH ++ DN I++SS D + +WD+ E G GH Sbjct: 127 GHTGYLSCCRFLDDNQ--IITSSGDTTCALWDI------------ETGQQTVGFAGHSGD 172 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASR 477 V + L+ DG+ +SG+ D ++LWD+ + + F+GHE D+ +VAF + + S Sbjct: 173 VMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSD 232 Query: 478 DRTIKLWN 501 D T +L++ Sbjct: 233 DATCRLFD 240 Score = 37.7 bits (86), Expect = 0.022 Identities = 18/68 (26%), Positives = 29/68 (42%) Frame = +1 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASR 477 + V S G+ L+G D +WD G GH+ V + + D + + S Sbjct: 259 ITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSW 318 Query: 478 DRTIKLWN 501 D +K+WN Sbjct: 319 DSFLKIWN 326 Score = 31.6 bits (70), Expect = 1.6 Identities = 12/33 (36%), Positives = 20/33 (60%) Frame = +1 Query: 277 LTGHGHFVQDVVLSSDGQFALSGSWDGELRLWD 375 L GH + V + ++ DG +GSWD L++W+ Sbjct: 294 LAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 326
>SCONB_EMENI (Q00659) Sulfur metabolite repression control protein| Length = 678 Score = 59.7 bits (143), Expect = 5e-09 Identities = 33/90 (36%), Positives = 47/90 (52%), Gaps = 1/90 (1%) Frame = +1 Query: 280 TGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQ 459 T GH + L + +GS+D +++WD TG R GHE + + F D+ + Sbjct: 344 TFKGHTNGVMCLQFEDNILATGSYDTTIKIWDTETGEELRTLRGHESGIRCLQF--DDTK 401 Query: 460 IVSASRDRTIKLWN-TLGECKYTIGGDLGG 546 ++S S DRTIK+WN GEC T G GG Sbjct: 402 LISGSMDRTIKVWNWRTGECISTYTGHRGG 431 Score = 52.0 bits (123), Expect = 1e-06 Identities = 37/140 (26%), Positives = 64/140 (45%) Frame = +1 Query: 115 RGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGH 294 +GH + V + DN + + S D ++ +WD +E G R L GH Sbjct: 346 KGHTNGVMCLQFE-DN--ILATGSYDTTIKIWD------------TETGEELRTLRGHES 390 Query: 295 FVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSAS 474 ++ L D +SGS D +++W+ TG + GH V+ + F D + S S Sbjct: 391 GIR--CLQFDDTKLISGSMDRTIKVWNWRTGECISTYTGHRGGVIGLHF--DASILASGS 446 Query: 475 RDRTIKLWNTLGECKYTIGG 534 D+T+K+WN + +++ G Sbjct: 447 VDKTVKIWNFEDKSTFSLRG 466 Score = 42.0 bits (97), Expect = 0.001 Identities = 40/145 (27%), Positives = 65/145 (44%), Gaps = 1/145 (0%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 +RGH + + D++ ++S S D+++ VW+ T + S Y TGH Sbjct: 385 LRGHESGIRCLQ--FDDTK-LISGSMDRTIKVWNWR-----TGECISTY-------TGHR 429 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSA 471 V + L D SGS D +++W+ +T GH V +V +R + SA Sbjct: 430 GGV--IGLHFDASILASGSVDKTVKIWNFEDK-STFSLRGHTDWVNAVRVDTSSRTVFSA 486 Query: 472 SRDRTIKLWN-TLGECKYTIGGDLG 543 S D T++LW+ C T G +G Sbjct: 487 SDDCTVRLWDLDTKTCIRTFHGHVG 511 Score = 38.1 bits (87), Expect = 0.017 Identities = 30/127 (23%), Positives = 55/127 (43%), Gaps = 5/127 (3%) Frame = +1 Query: 136 TAIATPIDNSP-----FIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFV 300 +A T DN ++V+S+ D ++ +W+ T G R GH V Sbjct: 565 SAFGTSFDNGRAAPPRYMVTSALDSTIRLWETTT------------GRCLRTFFGHLEGV 612 Query: 301 QDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRD 480 L +D +SG+ D +++WD TG R F GH V + + + + + S D Sbjct: 613 W--ALGADTLRIVSGAEDRMIKIWDPRTGKCERTFTGHSGPVTCI--GLGDSRFATGSED 668 Query: 481 RTIKLWN 501 +++++ Sbjct: 669 CEVRMYS 675 Score = 38.1 bits (87), Expect = 0.017 Identities = 27/92 (29%), Positives = 41/92 (44%) Frame = +1 Query: 160 NSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFAL 339 ++ + S S DK++ +W+ + + T S L GH +V V + + + Sbjct: 438 DASILASGSVDKTVKIWNFED-----KSTFS--------LRGHTDWVNAVRVDTSSRTVF 484 Query: 340 SGSWDGELRLWDLSTGVTTRRFVGHEKDVLSV 435 S S D +RLWDL T R F GH V V Sbjct: 485 SASDDCTVRLWDLDTKTCIRTFHGHVGQVQQV 516
>PRP46_YEAST (Q12417) Pre-mRNA-splicing factor PRP46 (Pre-mRNA-processing| protein 46) (Complexed with CEF1 protein 1) (PRP19-associated complex protein 50) (PRP nineteen-associated complex protein 50) Length = 451 Score = 59.7 bits (143), Expect = 5e-09 Identities = 44/133 (33%), Positives = 62/133 (46%), Gaps = 2/133 (1%) Frame = +1 Query: 109 VMRGHNDVVTAIAT-PIDNSPFIVSSSRDKSLLVWDL-TNPIQATQDTSSEYGVPFRRLT 282 V+ GH V +A P+DN FI S+ D ++ VWDL T ++ T L Sbjct: 134 VINGHLGWVRCVAIDPVDNEWFITGSN-DTTMKVWDLATGKLKTT-------------LA 179 Query: 283 GHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQI 462 GH V+DV +S + S S D ++ WDL R + GH V +V+ I Sbjct: 180 GHVMTVRDVAVSDRHPYLFSVSEDKTVKCWDLEKNQIIRDYYGHLSGVRTVSIHPTLDLI 239 Query: 463 VSASRDRTIKLWN 501 +A RD IKLW+ Sbjct: 240 ATAGRDSVIKLWD 252 Score = 54.3 bits (129), Expect = 2e-07 Identities = 36/132 (27%), Positives = 59/132 (44%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 + GH V +A D P++ S S DK++ WDL E R GH Sbjct: 178 LAGHVMTVRDVAVS-DRHPYLFSVSEDKTVKCWDL------------EKNQIIRDYYGHL 224 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSA 471 V+ V + + D ++LWD+ T + VGH+ + V + + Q+VS+ Sbjct: 225 SGVRTVSIHPTLDLIATAGRDSVIKLWDMRTRIPVITLVGHKGPINQVQCTPVDPQVVSS 284 Query: 472 SRDRTIKLWNTL 507 S D T++LW+ + Sbjct: 285 STDATVRLWDVV 296 Score = 49.3 bits (116), Expect = 7e-06 Identities = 26/78 (33%), Positives = 43/78 (55%), Gaps = 1/78 (1%) Frame = +1 Query: 271 RRLTGHGHFVQDVVLSS-DGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSI 447 R + GH +V+ V + D ++ ++GS D +++WDL+TG GH V VA S Sbjct: 133 RVINGHLGWVRCVAIDPVDNEWFITGSNDTTMKVWDLATGKLKTTLAGHVMTVRDVAVSD 192 Query: 448 DNRQIVSASRDRTIKLWN 501 + + S S D+T+K W+ Sbjct: 193 RHPYLFSVSEDKTVKCWD 210
>KTNB1_CHICK (Q5ZIU8) Katanin p80 WD40-containing subunit B1 (Katanin p80| subunit B1) (p80 katanin) Length = 657 Score = 59.7 bits (143), Expect = 5e-09 Identities = 42/144 (29%), Positives = 65/144 (45%), Gaps = 7/144 (4%) Frame = +1 Query: 133 VTAIATPIDN------SPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGH 294 +T TPI++ IV+ S+ S+ VWDL E R L GH Sbjct: 58 LTGHTTPIESLQISAKEELIVAGSQSGSIRVWDL------------EAAKILRTLLGHKA 105 Query: 295 FVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSAS 474 + + G F SGS D +++LWD+ ++ H + V + FS D + + SA+ Sbjct: 106 NICSLDFHPYGSFVASGSLDTDIKLWDVRRKGCIFKYKSHTQAVRCLRFSPDGKWLASAA 165 Query: 475 RDRTIKLWN-TLGECKYTIGGDLG 543 D T+KLW+ T G+ + G G Sbjct: 166 DDHTVKLWDLTAGKVMFEFTGHSG 189 Score = 52.8 bits (125), Expect = 7e-07 Identities = 36/130 (27%), Positives = 59/130 (45%), Gaps = 6/130 (4%) Frame = +1 Query: 130 VVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPF------RRLTGHG 291 VVT A + + SS SL++ T + AT + V LTGH Sbjct: 5 VVTKTAWKLQE--IVAHSSNVSSLVLGKSTGRLLATGGDDCQVNVWSVKAQLRHELTGHT 62 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSA 471 ++ + +S+ + ++GS G +R+WDL R +GH+ ++ S+ F + S Sbjct: 63 TPIESLQISAKEELIVAGSQSGSIRVWDLEAAKILRTLLGHKANICSLDFHPYGSFVASG 122 Query: 472 SRDRTIKLWN 501 S D IKLW+ Sbjct: 123 SLDTDIKLWD 132 Score = 52.0 bits (123), Expect = 1e-06 Identities = 33/111 (29%), Positives = 49/111 (44%) Frame = +1 Query: 169 FIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGS 348 F+ S S D + +WD+ G F+ H V+ + S DG++ S + Sbjct: 118 FVASGSLDTDIKLWDVRRK-----------GCIFK-YKSHTQAVRCLRFSPDGKWLASAA 165 Query: 349 WDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN 501 D ++LWDL+ G F GH V V F + S S DRTI+ W+ Sbjct: 166 DDHTVKLWDLTAGKVMFEFTGHSGPVNVVEFHPSEYLLASGSSDRTIRFWD 216 Score = 30.0 bits (66), Expect = 4.5 Identities = 23/88 (26%), Positives = 33/88 (37%) Frame = +1 Query: 115 RGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGH 294 + H V + D ++ S++ D ++ +WDLT G TGH Sbjct: 143 KSHTQAVRCLRFSPDGK-WLASAADDHTVKLWDLTA------------GKVMFEFTGHSG 189 Query: 295 FVQDVVLSSDGQFALSGSWDGELRLWDL 378 V V SGS D +R WDL Sbjct: 190 PVNVVEFHPSEYLLASGSSDRTIRFWDL 217
>GBB2_RAT (P54313) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 2 (Transducin beta chain 2) (G protein beta 2 subunit) Length = 339 Score = 59.7 bits (143), Expect = 5e-09 Identities = 36/128 (28%), Positives = 61/128 (47%) Frame = +1 Query: 118 GHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHF 297 GH ++ DN I++SS D + +WD+ E G GH Sbjct: 140 GHTGYLSCCRFLDDNQ--IITSSGDTTCALWDI------------ETGQQTVGFAGHSGD 185 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASR 477 V + L+ DG+ +SG+ D ++LWD+ + + F+GHE D+ +VAF + + S Sbjct: 186 VMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSD 245 Query: 478 DRTIKLWN 501 D T +L++ Sbjct: 246 DATCRLFD 253 Score = 37.7 bits (86), Expect = 0.022 Identities = 18/68 (26%), Positives = 29/68 (42%) Frame = +1 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASR 477 + V S G+ L+G D +WD G GH+ V + + D + + S Sbjct: 272 ITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSW 331 Query: 478 DRTIKLWN 501 D +K+WN Sbjct: 332 DSFLKIWN 339 Score = 31.6 bits (70), Expect = 1.6 Identities = 12/33 (36%), Positives = 20/33 (60%) Frame = +1 Query: 277 LTGHGHFVQDVVLSSDGQFALSGSWDGELRLWD 375 L GH + V + ++ DG +GSWD L++W+ Sbjct: 307 LAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 339
>GBB2_MOUSE (P62880) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 2 (Transducin beta chain 2) (G protein beta 2 subunit) Length = 339 Score = 59.7 bits (143), Expect = 5e-09 Identities = 36/128 (28%), Positives = 61/128 (47%) Frame = +1 Query: 118 GHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHF 297 GH ++ DN I++SS D + +WD+ E G GH Sbjct: 140 GHTGYLSCCRFLDDNQ--IITSSGDTTCALWDI------------ETGQQTVGFAGHSGD 185 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASR 477 V + L+ DG+ +SG+ D ++LWD+ + + F+GHE D+ +VAF + + S Sbjct: 186 VMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSD 245 Query: 478 DRTIKLWN 501 D T +L++ Sbjct: 246 DATCRLFD 253 Score = 37.7 bits (86), Expect = 0.022 Identities = 18/68 (26%), Positives = 29/68 (42%) Frame = +1 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASR 477 + V S G+ L+G D +WD G GH+ V + + D + + S Sbjct: 272 ITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSW 331 Query: 478 DRTIKLWN 501 D +K+WN Sbjct: 332 DSFLKIWN 339 Score = 31.6 bits (70), Expect = 1.6 Identities = 12/33 (36%), Positives = 20/33 (60%) Frame = +1 Query: 277 LTGHGHFVQDVVLSSDGQFALSGSWDGELRLWD 375 L GH + V + ++ DG +GSWD L++W+ Sbjct: 307 LAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 339
>GBB2_HUMAN (P62879) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 2 (Transducin beta chain 2) (G protein beta 2 subunit) Length = 339 Score = 59.7 bits (143), Expect = 5e-09 Identities = 36/128 (28%), Positives = 61/128 (47%) Frame = +1 Query: 118 GHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHF 297 GH ++ DN I++SS D + +WD+ E G GH Sbjct: 140 GHTGYLSCCRFLDDNQ--IITSSGDTTCALWDI------------ETGQQTVGFAGHSGD 185 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASR 477 V + L+ DG+ +SG+ D ++LWD+ + + F+GHE D+ +VAF + + S Sbjct: 186 VMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSD 245 Query: 478 DRTIKLWN 501 D T +L++ Sbjct: 246 DATCRLFD 253 Score = 37.7 bits (86), Expect = 0.022 Identities = 18/68 (26%), Positives = 29/68 (42%) Frame = +1 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASR 477 + V S G+ L+G D +WD G GH+ V + + D + + S Sbjct: 272 ITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSW 331 Query: 478 DRTIKLWN 501 D +K+WN Sbjct: 332 DSFLKIWN 339 Score = 31.6 bits (70), Expect = 1.6 Identities = 12/33 (36%), Positives = 20/33 (60%) Frame = +1 Query: 277 LTGHGHFVQDVVLSSDGQFALSGSWDGELRLWD 375 L GH + V + ++ DG +GSWD L++W+ Sbjct: 307 LAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 339
>GBB1_RAT (P54311) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 339 Score = 59.7 bits (143), Expect = 5e-09 Identities = 36/130 (27%), Positives = 60/130 (46%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 + GH ++ DN IV+SS D + +WD+ Q T TGH Sbjct: 138 LAGHTGYLSCCRFLDDNQ--IVTSSGDTTCALWDIETGQQTTT------------FTGHT 183 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSA 471 V + L+ D + +SG+ D +LWD+ G+ + F GHE D+ ++ F + + Sbjct: 184 GDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATG 243 Query: 472 SRDRTIKLWN 501 S D T +L++ Sbjct: 244 SDDATCRLFD 253 Score = 34.3 bits (77), Expect = 0.24 Identities = 17/68 (25%), Positives = 28/68 (41%) Frame = +1 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASR 477 + V S G+ L+G D +WD GH+ V + + D + + S Sbjct: 272 ITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSW 331 Query: 478 DRTIKLWN 501 D +K+WN Sbjct: 332 DSFLKIWN 339 Score = 31.6 bits (70), Expect = 1.6 Identities = 12/33 (36%), Positives = 20/33 (60%) Frame = +1 Query: 277 LTGHGHFVQDVVLSSDGQFALSGSWDGELRLWD 375 L GH + V + ++ DG +GSWD L++W+ Sbjct: 307 LAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 339
>GBB1_PONPY (Q5R5W8) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 339 Score = 59.7 bits (143), Expect = 5e-09 Identities = 36/130 (27%), Positives = 60/130 (46%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 + GH ++ DN IV+SS D + +WD+ Q T TGH Sbjct: 138 LAGHTGYLSCCRFLDDNQ--IVTSSGDTTCALWDIETGQQTTT------------FTGHT 183 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSA 471 V + L+ D + +SG+ D +LWD+ G+ + F GHE D+ ++ F + + Sbjct: 184 GDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATG 243 Query: 472 SRDRTIKLWN 501 S D T +L++ Sbjct: 244 SDDATCRLFD 253 Score = 33.9 bits (76), Expect = 0.31 Identities = 17/68 (25%), Positives = 28/68 (41%) Frame = +1 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASR 477 + V S G+ L+G D +WD GH+ V + + D + + S Sbjct: 272 ITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDDRVSCLGVTDDGMAVATGSW 331 Query: 478 DRTIKLWN 501 D +K+WN Sbjct: 332 DSFLKIWN 339 Score = 30.8 bits (68), Expect = 2.7 Identities = 12/33 (36%), Positives = 19/33 (57%) Frame = +1 Query: 277 LTGHGHFVQDVVLSSDGQFALSGSWDGELRLWD 375 L GH V + ++ DG +GSWD L++W+ Sbjct: 307 LAGHDDRVSCLGVTDDGMAVATGSWDSFLKIWN 339
>GBB1_MOUSE (P62874) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 339 Score = 59.7 bits (143), Expect = 5e-09 Identities = 36/130 (27%), Positives = 60/130 (46%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 + GH ++ DN IV+SS D + +WD+ Q T TGH Sbjct: 138 LAGHTGYLSCCRFLDDNQ--IVTSSGDTTCALWDIETGQQTTT------------FTGHT 183 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSA 471 V + L+ D + +SG+ D +LWD+ G+ + F GHE D+ ++ F + + Sbjct: 184 GDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATG 243 Query: 472 SRDRTIKLWN 501 S D T +L++ Sbjct: 244 SDDATCRLFD 253 Score = 34.3 bits (77), Expect = 0.24 Identities = 17/68 (25%), Positives = 28/68 (41%) Frame = +1 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASR 477 + V S G+ L+G D +WD GH+ V + + D + + S Sbjct: 272 ITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSW 331 Query: 478 DRTIKLWN 501 D +K+WN Sbjct: 332 DSFLKIWN 339 Score = 31.6 bits (70), Expect = 1.6 Identities = 12/33 (36%), Positives = 20/33 (60%) Frame = +1 Query: 277 LTGHGHFVQDVVLSSDGQFALSGSWDGELRLWD 375 L GH + V + ++ DG +GSWD L++W+ Sbjct: 307 LAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 339
>GBB1_HUMAN (P62873) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 339 Score = 59.7 bits (143), Expect = 5e-09 Identities = 36/130 (27%), Positives = 60/130 (46%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 + GH ++ DN IV+SS D + +WD+ Q T TGH Sbjct: 138 LAGHTGYLSCCRFLDDNQ--IVTSSGDTTCALWDIETGQQTTT------------FTGHT 183 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSA 471 V + L+ D + +SG+ D +LWD+ G+ + F GHE D+ ++ F + + Sbjct: 184 GDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATG 243 Query: 472 SRDRTIKLWN 501 S D T +L++ Sbjct: 244 SDDATCRLFD 253 Score = 34.3 bits (77), Expect = 0.24 Identities = 17/68 (25%), Positives = 28/68 (41%) Frame = +1 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASR 477 + V S G+ L+G D +WD GH+ V + + D + + S Sbjct: 272 ITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSW 331 Query: 478 DRTIKLWN 501 D +K+WN Sbjct: 332 DSFLKIWN 339 Score = 31.6 bits (70), Expect = 1.6 Identities = 12/33 (36%), Positives = 20/33 (60%) Frame = +1 Query: 277 LTGHGHFVQDVVLSSDGQFALSGSWDGELRLWD 375 L GH + V + ++ DG +GSWD L++W+ Sbjct: 307 LAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 339
>GBB1_CANFA (P62872) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 339 Score = 59.7 bits (143), Expect = 5e-09 Identities = 36/130 (27%), Positives = 60/130 (46%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 + GH ++ DN IV+SS D + +WD+ Q T TGH Sbjct: 138 LAGHTGYLSCCRFLDDNQ--IVTSSGDTTCALWDIETGQQTTT------------FTGHT 183 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSA 471 V + L+ D + +SG+ D +LWD+ G+ + F GHE D+ ++ F + + Sbjct: 184 GDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATG 243 Query: 472 SRDRTIKLWN 501 S D T +L++ Sbjct: 244 SDDATCRLFD 253 Score = 34.3 bits (77), Expect = 0.24 Identities = 17/68 (25%), Positives = 28/68 (41%) Frame = +1 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASR 477 + V S G+ L+G D +WD GH+ V + + D + + S Sbjct: 272 ITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSW 331 Query: 478 DRTIKLWN 501 D +K+WN Sbjct: 332 DSFLKIWN 339 Score = 31.6 bits (70), Expect = 1.6 Identities = 12/33 (36%), Positives = 20/33 (60%) Frame = +1 Query: 277 LTGHGHFVQDVVLSSDGQFALSGSWDGELRLWD 375 L GH + V + ++ DG +GSWD L++W+ Sbjct: 307 LAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 339
>GBB1_BOVIN (P62871) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 339 Score = 59.7 bits (143), Expect = 5e-09 Identities = 36/130 (27%), Positives = 60/130 (46%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 + GH ++ DN IV+SS D + +WD+ Q T TGH Sbjct: 138 LAGHTGYLSCCRFLDDNQ--IVTSSGDTTCALWDIETGQQTTT------------FTGHT 183 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSA 471 V + L+ D + +SG+ D +LWD+ G+ + F GHE D+ ++ F + + Sbjct: 184 GDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATG 243 Query: 472 SRDRTIKLWN 501 S D T +L++ Sbjct: 244 SDDATCRLFD 253 Score = 34.3 bits (77), Expect = 0.24 Identities = 17/68 (25%), Positives = 28/68 (41%) Frame = +1 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASR 477 + V S G+ L+G D +WD GH+ V + + D + + S Sbjct: 272 ITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSW 331 Query: 478 DRTIKLWN 501 D +K+WN Sbjct: 332 DSFLKIWN 339 Score = 31.6 bits (70), Expect = 1.6 Identities = 12/33 (36%), Positives = 20/33 (60%) Frame = +1 Query: 277 LTGHGHFVQDVVLSSDGQFALSGSWDGELRLWD 375 L GH + V + ++ DG +GSWD L++W+ Sbjct: 307 LAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 339
>GBB_MAIZE (P49178) Guanine nucleotide-binding protein beta subunit| Length = 380 Score = 59.7 bits (143), Expect = 5e-09 Identities = 43/133 (32%), Positives = 68/133 (51%), Gaps = 2/133 (1%) Frame = +1 Query: 109 VMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 ++ GH V++ D +++SS D++ ++WD+T T S +G F +GH Sbjct: 152 ILTGHKGYVSSCQYVPDQETRLITSSGDQTCVLWDVT-----TGQRISIFGGEFP--SGH 204 Query: 289 GHFVQDV-VLSSDGQFALSGSWDGELRLWDLS-TGVTTRRFVGHEKDVLSVAFSIDNRQI 462 VQ V + SS+ +SGS D +RLWD+ R + GHE DV SV F D + Sbjct: 205 TADVQSVSINSSNTNMFVSGSCDTTVRLWDIRIASRAVRTYHGHEDDVNSVKFFPDGHRF 264 Query: 463 VSASRDRTIKLWN 501 + S D T +L++ Sbjct: 265 GTGSDDGTCRLFD 277 Score = 46.6 bits (109), Expect = 5e-05 Identities = 39/138 (28%), Positives = 59/138 (42%), Gaps = 8/138 (5%) Frame = +1 Query: 118 GHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHF 297 GH V +++ N+ VS S D ++ +WD+ +A R GH Sbjct: 203 GHTADVQSVSINSSNTNMFVSGSCDTTVRLWDIRIASRAV-----------RTYHGHEDD 251 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKD--------VLSVAFSIDN 453 V V DG +GS DG RL+D+ TG + + E D V S+AFSI Sbjct: 252 VNSVKFFPDGHRFGTGSDDGTCRLFDMRTGHQLQVY-SREPDRNSNELPTVTSIAFSISG 310 Query: 454 RQIVSASRDRTIKLWNTL 507 R + + + +W+TL Sbjct: 311 RLLFAGYSNGDCYVWDTL 328 Score = 40.8 bits (94), Expect = 0.003 Identities = 49/181 (27%), Positives = 72/181 (39%), Gaps = 45/181 (24%) Frame = +1 Query: 94 LVYAGVMRGHNDVVTAIA-TPIDNSPFIVSSSRDKSLLVWD-LTNP-------------- 225 LV ++GH+ V ++ TP N +IVS+S+D L+VW+ LT+ Sbjct: 56 LVCCRTLQGHSGKVYSLDWTPEKN--WIVSASQDGRLIVWNALTSQKTHAIKLHCPWVMA 113 Query: 226 ---------------------IQATQDTSSEYGVPFRR-LTGHGHFVQDVVLSSDGQFAL 339 + +P R LTGH +V D + L Sbjct: 114 CAFAPNGQSVACGGLDSACSIFNLNSQADRDGNMPVSRILTGHKGYVSSCQYVPDQETRL 173 Query: 340 -SGSWDGELRLWDLSTGVTTRRF-----VGHEKDVLSVAFSIDN-RQIVSASRDRTIKLW 498 + S D LWD++TG F GH DV SV+ + N VS S D T++LW Sbjct: 174 ITSSGDQTCVLWDVTTGQRISIFGGEFPSGHTADVQSVSINSSNTNMFVSGSCDTTVRLW 233 Query: 499 N 501 + Sbjct: 234 D 234 Score = 30.0 bits (66), Expect = 4.5 Identities = 15/38 (39%), Positives = 19/38 (50%) Frame = +1 Query: 313 LSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDV 426 +SSDG +GSWD L++W F GH K V Sbjct: 352 MSSDGSALCTGSWDKNLKIW---------AFSGHRKIV 380 Score = 29.6 bits (65), Expect = 5.9 Identities = 15/40 (37%), Positives = 22/40 (55%) Frame = +1 Query: 388 VTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNTL 507 V R GH V S+ ++ + IVSAS+D + +WN L Sbjct: 57 VCCRTLQGHSGKVYSLDWTPEKNWIVSASQDGRLIVWNAL 96
>MORG1_HUMAN (Q9BRX9) Mitogen-activated protein kinase organizer 1 (MAPK| organizer 1) Length = 315 Score = 59.7 bits (143), Expect = 5e-09 Identities = 38/123 (30%), Positives = 62/123 (50%) Frame = +1 Query: 133 VTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVV 312 V A+ +D + + ++ DK+L +W NP++ T R +GHG+ V D Sbjct: 28 VRAVRFNVDGN-YCLTCGSDKTLKLW---NPLRGTL---------LRTYSGHGYEVLDAA 74 Query: 313 LSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIK 492 S D SG D + LWD+++G R+F GH V +V F+ + I+S S D +I+ Sbjct: 75 GSFDNSSLCSGGGDKAVVLWDVASGQVVRKFRGHAGKVNTVQFNEEATVILSGSIDSSIR 134 Query: 493 LWN 501 W+ Sbjct: 135 CWD 137 Score = 38.5 bits (88), Expect = 0.013 Identities = 41/161 (25%), Positives = 58/161 (36%), Gaps = 32/161 (19%) Frame = +1 Query: 115 RGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTN----PIQATQDTSSEYGVPFRRLT 282 RGH V + + + I+S S D S+ WD + P+Q + GV +++ Sbjct: 106 RGHAGKVNTVQFN-EEATVILSGSIDSSIRCWDCRSRRPEPVQTLDEARD--GVSSVKVS 162 Query: 283 GH------------------GHFVQDVV--------LSSDGQFALSGSWDGELRLWDLST 384 H G D V S DGQ L S D LRL D T Sbjct: 163 DHEILAGSVDGRVRRYDLRMGQLFSDYVGSPITCTCFSRDGQCTLVSSLDSTLRLLDKDT 222 Query: 385 GVTTRRFVGHEKD--VLSVAFSIDNRQIVSASRDRTIKLWN 501 G + GH+ L S + +VS S D + W+ Sbjct: 223 GELLGEYKGHKNQEYKLDCCLSERDTHVVSCSEDGKVFFWD 263 Score = 29.6 bits (65), Expect = 5.9 Identities = 11/28 (39%), Positives = 18/28 (64%) Frame = +1 Query: 424 VLSVAFSIDNRQIVSASRDRTIKLWNTL 507 V +V F++D ++ D+T+KLWN L Sbjct: 28 VRAVRFNVDGNYCLTCGSDKTLKLWNPL 55
>TRCB_XENLA (Q91854) Beta-TrCP (Beta-transducin repeat-containing protein)| Length = 518 Score = 59.7 bits (143), Expect = 5e-09 Identities = 46/150 (30%), Positives = 73/150 (48%) Frame = +1 Query: 52 RSLRHTTMAGAQESLVYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQ 231 RS+ MA A + + V+ GH V + + +IVS+S D+++ VW+ + Sbjct: 332 RSIAVWDMASATD-ITLRRVLVGHRAAVNVVDF---DDKYIVSASGDRTIKVWNTS---- 383 Query: 232 ATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVG 411 + E+ R L GH + L + +SGS D +RLWD+ G R G Sbjct: 384 -----TCEF---VRTLNGHKRGI--ACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEG 433 Query: 412 HEKDVLSVAFSIDNRQIVSASRDRTIKLWN 501 HE+ V + F DN++IVS + D IK+W+ Sbjct: 434 HEELVRCIRF--DNKRIVSGAYDGKIKVWD 461 Score = 52.4 bits (124), Expect = 9e-07 Identities = 37/123 (30%), Positives = 58/123 (47%), Gaps = 9/123 (7%) Frame = +1 Query: 172 IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSW 351 +VS S D ++ +WD+ E G R L GH V+ + D + +SG++ Sbjct: 408 VVSGSSDNTIRLWDI------------ECGACLRVLEGHEELVR--CIRFDNKRIVSGAY 453 Query: 352 DGELRLWDLSTG---------VTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNT 504 DG++++WDL + R V H V + F D QIVS+S D TI +W+ Sbjct: 454 DGKIKVWDLVAALDPRAPAGTLCLRTLVEHSGRVFRLQF--DEFQIVSSSHDDTILIWDF 511 Query: 505 LGE 513 L + Sbjct: 512 LND 514 Score = 51.2 bits (121), Expect = 2e-06 Identities = 35/119 (29%), Positives = 59/119 (49%) Frame = +1 Query: 172 IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSW 351 IVS RD ++ +WD N ++ R L GH V + L D + ++GS Sbjct: 245 IVSGLRDNTIKIWD-KNTLECK-----------RVLMGHTGSV--LCLQYDERVIITGSS 290 Query: 352 DGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNTLGECKYTI 528 D +R+WD++TG + H + VL + F +N +V+ S+DR+I +W+ T+ Sbjct: 291 DSTVRVWDVNTGEMLNTLIHHCEAVLHLRF--NNGMMVTCSKDRSIAVWDMASATDITL 347 Score = 49.7 bits (117), Expect = 6e-06 Identities = 47/151 (31%), Positives = 70/151 (46%), Gaps = 5/151 (3%) Frame = +1 Query: 109 VMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 V+ GH V + + I++ S D ++ VWD+ G L H Sbjct: 267 VLMGHTGSVLCLQY---DERVIITGSSDSTVRVWDVNT------------GEMLNTLIHH 311 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDLS--TGVTTRR-FVGHEKDVLSVAFSIDNRQ 459 V + L + ++ S D + +WD++ T +T RR VGH V V F D++ Sbjct: 312 CEAV--LHLRFNNGMMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDF--DDKY 367 Query: 460 IVSASRDRTIKLWNTLGECKY--TIGGDLGG 546 IVSAS DRTIK+WNT C++ T+ G G Sbjct: 368 IVSASGDRTIKVWNT-STCEFVRTLNGHKRG 397 Score = 42.0 bits (97), Expect = 0.001 Identities = 21/63 (33%), Positives = 35/63 (55%) Frame = +1 Query: 313 LSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIK 492 L D Q +SG D +++WD +T R +GH VL + + D R I++ S D T++ Sbjct: 238 LQYDDQKIVSGLRDNTIKIWDKNTLECKRVLMGHTGSVLCLQY--DERVIITGSSDSTVR 295 Query: 493 LWN 501 +W+ Sbjct: 296 VWD 298
>LIN23_CAEEL (Q09990) F-box/WD-repeat protein lin-23 (Abnormal cell lineage| protein 23) Length = 665 Score = 59.7 bits (143), Expect = 5e-09 Identities = 42/131 (32%), Positives = 66/131 (50%) Frame = +1 Query: 109 VMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 V+ GH V + + +IVS+S D+++ VW + + E+ R L GH Sbjct: 340 VLVGHRAAVNVVDF---DDRYIVSASGDRTIKVWSMD---------TLEF---VRTLAGH 384 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVS 468 + L G+ +SGS D +RLWD+ +GV R GHE+ V + F D ++IVS Sbjct: 385 RRGI--ACLQYRGRLVVSGSSDNTIRLWDIHSGVCLRVLEGHEELVRCIRF--DEKRIVS 440 Query: 469 ASRDRTIKLWN 501 + D IK+W+ Sbjct: 441 GAYDGKIKVWD 451 Score = 53.9 bits (128), Expect = 3e-07 Identities = 38/119 (31%), Positives = 61/119 (51%) Frame = +1 Query: 172 IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSW 351 IVS RD ++ +WD +D S R L+GH V + L D + +SGS Sbjct: 235 IVSGLRDNTIKIWD-------RKDYSCS-----RILSGHTGSV--LCLQYDNRVIISGSS 280 Query: 352 DGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNTLGECKYTI 528 D +R+WD+ TG + + H + VL + F+ N +V+ S+DR+I +W+ + TI Sbjct: 281 DATVRVWDVETGECIKTLIHHCEAVLHLRFA--NGIMVTCSKDRSIAVWDMVSPRDITI 337 Score = 53.1 bits (126), Expect = 5e-07 Identities = 41/156 (26%), Positives = 70/156 (44%), Gaps = 9/156 (5%) Frame = +1 Query: 67 TTMAGAQESLVYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDT 246 T + ++L + + GH + + +VS S D ++ +WD+ + Sbjct: 366 TIKVWSMDTLEFVRTLAGHRRGIACLQY---RGRLVVSGSSDNTIRLWDIHS-------- 414 Query: 247 SSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTR--------- 399 GV R L GH V+ + D + +SG++DG++++WDL + R Sbjct: 415 ----GVCLRVLEGHEELVR--CIRFDEKRIVSGAYDGKIKVWDLQAALDPRALSSEICLC 468 Query: 400 RFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNTL 507 V H V + F D+ QIVS+S D TI +W+ L Sbjct: 469 SLVQHTGRVFRLQF--DDFQIVSSSHDDTILIWDFL 502 Score = 44.3 bits (103), Expect = 2e-04 Identities = 25/73 (34%), Positives = 38/73 (52%), Gaps = 1/73 (1%) Frame = +1 Query: 313 LSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIK 492 L D +SG D +++WD +R GH VL + + DNR I+S S D T++ Sbjct: 228 LQYDDDKIVSGLRDNTIKIWDRKDYSCSRILSGHTGSVLCLQY--DNRVIISGSSDATVR 285 Query: 493 LWNT-LGECKYTI 528 +W+ GEC T+ Sbjct: 286 VWDVETGECIKTL 298
>PRP46_ASHGO (Q75BY3) Pre-mRNA-splicing factor PRP46 (Pre-mRNA-processing| protein 46) Length = 425 Score = 59.7 bits (143), Expect = 5e-09 Identities = 45/148 (30%), Positives = 66/148 (44%), Gaps = 3/148 (2%) Frame = +1 Query: 109 VMRGHNDVVTAIAT-PIDNSPFIVSSSRDKSLLVWDL-TNPIQATQDTSSEYGVPFRRLT 282 V+ GH V + P+DN+ F + S D ++ VWDL T ++ T L Sbjct: 108 VINGHTGWVRCVCVDPVDNAWF-ATGSNDSTIRVWDLATGKLKVT-------------LQ 153 Query: 283 GHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQI 462 GH V+D+ +S+ + S S D ++ WDL R F G V SV I Sbjct: 154 GHIMTVRDICISARHPYMFSASQDKLVKCWDLERNTVVRDFHGTLSGVHSVDLHPSLDLI 213 Query: 463 VSASRDRTIKLWNTLG-ECKYTIGGDLG 543 VSA RD +++W+ C T+ G G Sbjct: 214 VSAGRDSVVRVWDIRSRSCVLTLAGHRG 241 Score = 45.1 bits (105), Expect = 1e-04 Identities = 32/112 (28%), Positives = 46/112 (41%) Frame = +1 Query: 166 PFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSG 345 P++ S+S+DK + WDL E R G V V L +S Sbjct: 169 PYMFSASQDKLVKCWDL------------ERNTVVRDFHGTLSGVHSVDLHPSLDLIVSA 216 Query: 346 SWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN 501 D +R+WD+ + GH + V + QIVS S D T+KLW+ Sbjct: 217 GRDSVVRVWDIRSRSCVLTLAGHRGPINKVRCLPVDPQIVSCSTDATVKLWD 268 Score = 35.8 bits (81), Expect = 0.083 Identities = 41/168 (24%), Positives = 65/168 (38%), Gaps = 39/168 (23%) Frame = +1 Query: 112 MRGHNDVVTAI-ATPIDNSPFIVSSSRDKSLLVWDLT--------------------NPI 228 + GH + + P+D P IVS S D ++ +WDL NP Sbjct: 236 LAGHRGPINKVRCLPVD--PQIVSCSTDATVKLWDLVAGKPMKTLTHHKRNVRDLAFNPT 293 Query: 229 Q------ATQDTSSEYGVPFRRLTGHGH----FVQDVVLSSDGQFALSGSWDGELRLWDL 378 + T D S V + LT V + + DG +G GEL +D Sbjct: 294 EFSFASACTDDIRSWKLVDGQLLTNFNSEALGIVNTLACNQDG-VLFAGGDTGELSFFDY 352 Query: 379 STGVTTRRF--------VGHEKDVLSVAFSIDNRQIVSASRDRTIKLW 498 TG ++ + EK VL+ F ++++ RD++IK+W Sbjct: 353 KTGHKFQKLETTAMPGSLESEKGVLASTFDRTGLRLLTCERDKSIKIW 400
>GBB_LYMST (Q08706) Guanine nucleotide-binding protein beta subunit| Length = 341 Score = 59.3 bits (142), Expect = 7e-09 Identities = 39/128 (30%), Positives = 62/128 (48%) Frame = +1 Query: 118 GHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHF 297 GH ++ DNS IV+SS D S +WD I+ Q T+S TGH Sbjct: 142 GHTGYLSCCRFIDDNS--IVTSSGDMSCALWD----IETGQQTTS--------FTGHTGD 187 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASR 477 V + S D + +SG+ D +LWD+ G+ + F GHE D+ ++ + + + S Sbjct: 188 VMSLSTSPDFRTFVSGACDASAKLWDVRDGMCKQTFSGHESDINAITYFPNGHAFATGSD 247 Query: 478 DRTIKLWN 501 D T +L++ Sbjct: 248 DATCRLFD 255 Score = 58.5 bits (140), Expect = 1e-08 Identities = 55/176 (31%), Positives = 72/176 (40%), Gaps = 35/176 (19%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWD--LTNPIQATQDTSS----------- 252 +RGH + A+ D S +VS+S+D L+VWD TN + A SS Sbjct: 52 LRGHLAKIYAMHWASD-SRNLVSASQDGKLIVWDGYTTNKVHAIPLRSSWVMTCAYAPSG 110 Query: 253 --------------------EYGVPF-RRLTGHGHFVQDVVLSSDGQFALSGSWDGELRL 369 E V R L GH ++ D S S D L Sbjct: 111 NFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFIDDNSIVTS-SGDMSCAL 169 Query: 370 WDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNTL-GECKYTIGG 534 WD+ TG T F GH DV+S++ S D R VS + D + KLW+ G CK T G Sbjct: 170 WDIETGQQTTSFTGHTGDVMSLSTSPDFRTFVSGACDASAKLWDVRDGMCKQTFSG 225 Score = 33.5 bits (75), Expect = 0.41 Identities = 17/68 (25%), Positives = 28/68 (41%) Frame = +1 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASR 477 + V S G+ L D +WD+ T GH+ V + + D + + S Sbjct: 274 ITSVAFSKSGRLLLGRYDDFNCNVWDVLKQETHGVLAGHDNRVSCLGVTEDGSAVATGSW 333 Query: 478 DRTIKLWN 501 D +K+WN Sbjct: 334 DSFLKIWN 341 Score = 32.7 bits (73), Expect = 0.70 Identities = 23/90 (25%), Positives = 43/90 (47%), Gaps = 2/90 (2%) Frame = +1 Query: 112 MRGHNDVVTAIATPI--DNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTG 285 M H++++ I + + ++ D + VWD+ Q+T +GV L G Sbjct: 264 MYSHDNIICGITSVAFSKSGRLLLGRYDDFNCNVWDVLK-----QET---HGV----LAG 311 Query: 286 HGHFVQDVVLSSDGQFALSGSWDGELRLWD 375 H + V + ++ DG +GSWD L++W+ Sbjct: 312 HDNRVSCLGVTEDGSAVATGSWDSFLKIWN 341
>TIPD_DICDI (O15736) Protein tipD| Length = 612 Score = 59.3 bits (142), Expect = 7e-09 Identities = 28/92 (30%), Positives = 52/92 (56%), Gaps = 1/92 (1%) Frame = +1 Query: 271 RRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSID 450 +R TGH + + +S G +G D +++WD+ +G +G + ++SV+FS + Sbjct: 318 KRWTGHNSEIYCMAFNSIGNLLATGGGDKCVKVWDVISGQQKSTLLGASQSIVSVSFSPN 377 Query: 451 NRQIVSASRDRTIKLWNT-LGECKYTIGGDLG 543 + I+ S D + +LWNT LG ++T+ G +G Sbjct: 378 DESILGTSNDNSARLWNTELGRSRHTLTGHIG 409 Score = 50.4 bits (119), Expect = 3e-06 Identities = 41/139 (29%), Positives = 61/139 (43%), Gaps = 2/139 (1%) Frame = +1 Query: 118 GHNDVVTAIA-TPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGH 294 GHN + +A I N + + DK + VWD+ + Q + L G Sbjct: 322 GHNSEIYCMAFNSIGN--LLATGGGDKCVKVWDVISGQQKST------------LLGASQ 367 Query: 295 FVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSAS 474 + V S + + L S D RLW+ G + GH V + F I++ ++V+ S Sbjct: 368 SIVSVSFSPNDESILGTSNDNSARLWNTELGRSRHTLTGHIGKVYTGKF-INSNRVVTGS 426 Query: 475 RDRTIKLWN-TLGECKYTI 528 DRTIKLW+ G C TI Sbjct: 427 HDRTIKLWDLQKGYCTRTI 445 Score = 43.1 bits (100), Expect = 5e-04 Identities = 35/129 (27%), Positives = 59/129 (45%), Gaps = 3/129 (2%) Frame = +1 Query: 121 HNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFV 300 H +T+I N+ I+++SRD +L + D+ T DT + P R +G Sbjct: 491 HEGQITSITNSPTNTNQILTNSRDHTLKIIDIR-----TFDTIRTFKDPEYR---NGLNW 542 Query: 301 QDVVLSSDGQFALSGSWDGELRLWDLSTGVTTR---RFVGHEKDVLSVAFSIDNRQIVSA 471 S DG++ SGS DG + +WD + G T + + + V ++S +SA Sbjct: 543 TKASWSPDGRYIASGSIDGSICIWDATNGKTVKVLTKVHNNGSSVCCCSWSPLANIFISA 602 Query: 472 SRDRTIKLW 498 +D+ I W Sbjct: 603 DKDKNIIQW 611
>FBW1B_HUMAN (Q9UKB1) F-box/WD-repeat protein 11 (F-box/WD-repeat protein 1B)| (F-box and WD-repeats protein beta-TrCP2) Length = 542 Score = 59.3 bits (142), Expect = 7e-09 Identities = 46/150 (30%), Positives = 72/150 (48%) Frame = +1 Query: 52 RSLRHTTMAGAQESLVYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQ 231 RS+ MA A + + V+ GH V + + +IVS+S D+++ VW + Sbjct: 340 RSIAVWDMASATD-ITLRRVLVGHRAAVNVVDF---DDKYIVSASGDRTIKVWSTS---- 391 Query: 232 ATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVG 411 + E+ R L GH + L + +SGS D +RLWD+ G R G Sbjct: 392 -----TCEF---VRTLNGHKRGI--ACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEG 441 Query: 412 HEKDVLSVAFSIDNRQIVSASRDRTIKLWN 501 HE+ V + F DN++IVS + D IK+W+ Sbjct: 442 HEELVRCIRF--DNKRIVSGAYDGKIKVWD 469 Score = 55.8 bits (133), Expect = 8e-08 Identities = 38/119 (31%), Positives = 60/119 (50%) Frame = +1 Query: 172 IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSW 351 I+S RD S+ +WD TS E + LTGH V + L D + ++GS Sbjct: 253 IISGLRDNSIKIWD---------KTSLEC---LKVLTGHTGSV--LCLQYDERVIVTGSS 298 Query: 352 DGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNTLGECKYTI 528 D +R+WD++TG + H + VL + FS N +V+ S+DR+I +W+ T+ Sbjct: 299 DSTVRVWDVNTGEVLNTLIHHNEAVLHLRFS--NGLMVTCSKDRSIAVWDMASATDITL 355 Score = 52.0 bits (123), Expect = 1e-06 Identities = 36/121 (29%), Positives = 59/121 (48%), Gaps = 9/121 (7%) Frame = +1 Query: 172 IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSW 351 +VS S D ++ +WD+ E G R L GH V+ + D + +SG++ Sbjct: 416 VVSGSSDNTIRLWDI------------ECGACLRVLEGHEELVR--CIRFDNKRIVSGAY 461 Query: 352 DGELRLWDL---------STGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNT 504 DG++++WDL ++ + R V H V + F D QI+S+S D TI +W+ Sbjct: 462 DGKIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRLQF--DEFQIISSSHDDTILIWDF 519 Query: 505 L 507 L Sbjct: 520 L 520 Score = 38.9 bits (89), Expect = 0.010 Identities = 19/63 (30%), Positives = 34/63 (53%) Frame = +1 Query: 313 LSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIK 492 L D + +SG D +++WD ++ + GH VL + + D R IV+ S D T++ Sbjct: 246 LQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQY--DERVIVTGSSDSTVR 303 Query: 493 LWN 501 +W+ Sbjct: 304 VWD 306
>MET30_YEAST (P39014) F-box protein MET30 (Methionine requiring protein 30) (E3| ubiquitin ligase complex SCF(Met30) subunit MET30) Length = 640 Score = 59.3 bits (142), Expect = 7e-09 Identities = 43/140 (30%), Positives = 65/140 (46%) Frame = +1 Query: 115 RGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGH 294 +GH D V + N + + S D ++ +WDL G RRL+GH Sbjct: 299 KGHMDGVLTLQF---NYRLLFTGSYDSTIGIWDLFT------------GKLIRRLSGHSD 343 Query: 295 FVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSAS 474 V+ L D + ++GS D +R+W+ TG + GH VLSV + IVS S Sbjct: 344 GVK--TLYFDDRKLITGSLDKTIRVWNYITGECISTYRGHSDSVLSV--DSYQKVIVSGS 399 Query: 475 RDRTIKLWNTLGECKYTIGG 534 D+T+K+W+ YT+ G Sbjct: 400 ADKTVKVWHVESRTCYTLRG 419 Score = 48.1 bits (113), Expect = 2e-05 Identities = 26/67 (38%), Positives = 38/67 (56%), Gaps = 1/67 (1%) Frame = +1 Query: 337 LSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN-TLGE 513 LS D ++LWD+ TG R GH + V +A DN +I+S S D +IK+W+ G+ Sbjct: 526 LSCGLDNTIKLWDVKTGKCIRTQFGHVEGVWDIA--ADNFRIISGSHDGSIKVWDLQSGK 583 Query: 514 CKYTIGG 534 C +T G Sbjct: 584 CMHTFNG 590 Score = 39.3 bits (90), Expect = 0.007 Identities = 31/107 (28%), Positives = 45/107 (42%) Frame = +1 Query: 115 RGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGH 294 RGH+D V ++ + IVS S DK++ VW + + T L GH Sbjct: 379 RGHSDSVLSVDS---YQKVIVSGSADKTVKVWHVESRTCYT-------------LRGHTE 422 Query: 295 FVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSV 435 +V V L S S D +R+WD+ T + F GH V + Sbjct: 423 WVNCVKLHPKSFSCFSCSDDTTIRMWDIRTNSCLKVFRGHVGQVQKI 469 Score = 35.8 bits (81), Expect = 0.083 Identities = 25/96 (26%), Positives = 41/96 (42%) Frame = +1 Query: 124 NDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQ 303 N+ T + I ++S D ++ +WD+ G R GH V Sbjct: 509 NEQETVLDENIPYPTHLLSCGLDNTIKLWDVKT------------GKCIRTQFGHVEGVW 556 Query: 304 DVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVG 411 D+ ++D +SGS DG +++WDL +G F G Sbjct: 557 DI--AADNFRIISGSHDGSIKVWDLQSGKCMHTFNG 590
>GBB1_XENLA (P79959) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) (XGbeta1) Length = 340 Score = 59.3 bits (142), Expect = 7e-09 Identities = 35/130 (26%), Positives = 60/130 (46%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 + GH ++ DN I++SS D + +WD+ Q T TGH Sbjct: 139 LAGHTGYLSCCRFLDDNQ--IITSSGDTTCALWDIETGQQTTT------------FTGHT 184 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSA 471 V + L+ D + +SG+ D +LWD+ G+ + F GHE D+ ++ F + + Sbjct: 185 GDVMSLSLAPDSRCFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATG 244 Query: 472 SRDRTIKLWN 501 S D T +L++ Sbjct: 245 SDDATCRLFD 254 Score = 35.0 bits (79), Expect = 0.14 Identities = 17/68 (25%), Positives = 28/68 (41%) Frame = +1 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASR 477 + V S G+ L+G D +WD GH+ V + + D + + S Sbjct: 273 ITSVAFSKSGRLLLAGYDDFNCNVWDTLKADRAGVLAGHDNRVSCLGVTDDGMAVATGSW 332 Query: 478 DRTIKLWN 501 D +K+WN Sbjct: 333 DSFLKIWN 340 Score = 33.1 bits (74), Expect = 0.54 Identities = 25/99 (25%), Positives = 46/99 (46%), Gaps = 2/99 (2%) Frame = +1 Query: 85 QESLVYAGVMRGHNDVVTAIATPI--DNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEY 258 QE +VY+ H++++ I + + +++ D + VWD +A Sbjct: 259 QELMVYS-----HDNIICGITSVAFSKSGRLLLAGYDDFNCNVWDTLKADRA-------- 305 Query: 259 GVPFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWD 375 GV L GH + V + ++ DG +GSWD L++W+ Sbjct: 306 GV----LAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
>GBB1_HOMAM (O45040) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 340 Score = 59.3 bits (142), Expect = 7e-09 Identities = 38/128 (29%), Positives = 59/128 (46%) Frame = +1 Query: 118 GHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHF 297 GH ++ DN IV+SS D + +WD+ Q TQ TGH Sbjct: 141 GHTGYLSCCRFVDDNQ--IVTSSGDMTCALWDIETGQQCTQ------------FTGHTGD 186 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASR 477 V + LS + + SG+ D +LWD+ G+ + F GHE D+ +V F + + S Sbjct: 187 VMSLSLSPNMRTFTSGACDASAKLWDIRDGMCRQTFPGHESDINAVTFFPNGHAFATGSD 246 Query: 478 DRTIKLWN 501 D T +L++ Sbjct: 247 DATCRLFD 254 Score = 34.7 bits (78), Expect = 0.18 Identities = 17/68 (25%), Positives = 28/68 (41%) Frame = +1 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASR 477 + V S G+ L+G D +WD GH+ V + + D + + S Sbjct: 273 ITSVAFSKSGKLLLAGYDDFNCNVWDSMRTERAGVLAGHDNRVSCLGVTEDGMAVATGSW 332 Query: 478 DRTIKLWN 501 D +K+WN Sbjct: 333 DSFLKIWN 340 Score = 32.0 bits (71), Expect = 1.2 Identities = 22/90 (24%), Positives = 41/90 (45%), Gaps = 2/90 (2%) Frame = +1 Query: 112 MRGHNDVVTAIATPI--DNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTG 285 M H++++ I + + +++ D + VWD +A GV L G Sbjct: 263 MYSHDNIICGITSVAFSKSGKLLLAGYDDFNCNVWDSMRTERA--------GV----LAG 310 Query: 286 HGHFVQDVVLSSDGQFALSGSWDGELRLWD 375 H + V + ++ DG +GSWD L++W+ Sbjct: 311 HDNRVSCLGVTEDGMAVATGSWDSFLKIWN 340
>GBB_NICPL (P93339) Guanine nucleotide-binding protein beta subunit (NpGPB1)| Length = 377 Score = 58.5 bits (140), Expect = 1e-08 Identities = 41/133 (30%), Positives = 69/133 (51%), Gaps = 2/133 (1%) Frame = +1 Query: 109 VMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 ++ GH V++ D +++SS D++ ++WD+T ++ +S +G F+ GH Sbjct: 151 MLSGHKGYVSSCQYVPDEDTHLITSSGDQTCVLWDITTGLR-----TSVFGGEFQ--FGH 203 Query: 289 GHFVQDV-VLSSDGQFALSGSWDGELRLWDLSTGVTTRR-FVGHEKDVLSVAFSIDNRQI 462 VQ V + SS+ + +SGS D RLWD +R F HE DV +V F D + Sbjct: 204 TADVQSVSISSSNPRLFVSGSCDTTARLWDTRVASRAQRTFYCHEGDVNTVKFFPDGNRF 263 Query: 463 VSASRDRTIKLWN 501 + S D T +L++ Sbjct: 264 GTGSEDGTCRLFD 276 Score = 47.4 bits (111), Expect = 3e-05 Identities = 54/197 (27%), Positives = 80/197 (40%), Gaps = 46/197 (23%) Frame = +1 Query: 52 RSLRHTTMAGAQESLVYAGVMRGHNDVVTAIA-TPIDNSPFIVSSSRDKSLLVWD-LTNP 225 RS T + LV +++GH V ++ TP N IVS+S+D L+VW+ LT+ Sbjct: 41 RSQGKTPVTFGPTDLVCCRILQGHTGKVYSLDWTPEKNR--IVSASQDGRLIVWNALTSQ 98 Query: 226 -------------------------------------IQATQDTSSEYGVPFRRLTGHGH 294 + + D + V R L+GH Sbjct: 99 KTHAIKLPCAWVMTCAFSPSGHSVACGGLDSVCSIFNLNSPIDKDGNHPVS-RMLSGHKG 157 Query: 295 FVQDV-VLSSDGQFALSGSWDGELRLWDLSTGVTTRRF-----VGHEKDVLSVAFSIDN- 453 +V + + ++ S D LWD++TG+ T F GH DV SV+ S N Sbjct: 158 YVSSCQYVPDEDTHLITSSGDQTCVLWDITTGLRTSVFGGEFQFGHTADVQSVSISSSNP 217 Query: 454 RQIVSASRDRTIKLWNT 504 R VS S D T +LW+T Sbjct: 218 RLFVSGSCDTTARLWDT 234 Score = 29.6 bits (65), Expect = 5.9 Identities = 15/40 (37%), Positives = 23/40 (57%) Frame = +1 Query: 388 VTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNTL 507 V R GH V S+ ++ + +IVSAS+D + +WN L Sbjct: 56 VCCRILQGHTGKVYSLDWTPEKNRIVSASQDGRLIVWNAL 95
>ATG16_XENTR (Q5I0B9) Autophagy-related protein 16 (APG16-like 1)| Length = 537 Score = 58.5 bits (140), Expect = 1e-08 Identities = 49/168 (29%), Positives = 71/168 (42%), Gaps = 4/168 (2%) Frame = +1 Query: 10 SLRRRLHRTPRKP*RSLRHTTMAGAQESLVYAGVMRG---HNDVVTAIATPIDNSPFIVS 180 S RR L+ P P T AG +E V A + H+ V A+ S + + Sbjct: 213 SKRRSLNSFPASP--DCADTPGAGNREVRVPATAVYSFDAHDGEVNAVRFS-PGSRLLAT 269 Query: 181 SSRDKSLLVWDLT-NPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSWDG 357 D+ + +WD+ N +A LTG + + S G + L+ S D Sbjct: 270 GGMDRRVKLWDVIGNKCEAKGS-----------LTGSNAGITSIEFDSAGSYLLAASNDF 318 Query: 358 ELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN 501 R+W + GH VLS F +DN +IVS S DRT+KLW+ Sbjct: 319 ASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWD 366 Score = 43.5 bits (101), Expect = 4e-04 Identities = 33/128 (25%), Positives = 61/128 (47%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 + GH+ V + +DN+ IVS S D++L +WDL + + + G Sbjct: 334 LTGHSGKVLSAKFLLDNAR-IVSGSHDRTLKLWDLRSKVCI-------------KTVFAG 379 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSA 471 D+V + Q +SG +D ++R WD+ T R + + + ++ + + Q++S Sbjct: 380 SSCNDIVCTE--QCVMSGHFDKKIRFWDIRTECIVRE-LELQGRITALDLNPERTQLLSC 436 Query: 472 SRDRTIKL 495 SRD IK+ Sbjct: 437 SRDDLIKI 444 Score = 42.4 bits (98), Expect = 9e-04 Identities = 33/111 (29%), Positives = 49/111 (44%), Gaps = 1/111 (0%) Frame = +1 Query: 172 IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSW 351 ++S SRD + + DL A Q T S G G V+ S DG + +GS Sbjct: 433 LLSCSRDDLIKITDLR--ANAVQQTFSAPGFKC------GSDWTRVIFSPDGSYVSAGSA 484 Query: 352 DGELRLWDLSTGVTTRRF-VGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN 501 +G L W++ TG R F H + +VA+S +VS + LW+ Sbjct: 485 EGTLYFWNVLTGKVERMFSKQHSSSINAVAWSPSGTHVVSVDKGSRGVLWS 535 Score = 38.1 bits (87), Expect = 0.017 Identities = 36/139 (25%), Positives = 60/139 (43%), Gaps = 2/139 (1%) Frame = +1 Query: 106 GVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTG 285 G + G N +T+I S +++++S D + +W T +Y + LTG Sbjct: 290 GSLTGSNAGITSIEFDSAGS-YLLAASNDFASRIW-----------TVDDYRLR-HTLTG 336 Query: 286 HGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRR-FVGHE-KDVLSVAFSIDNRQ 459 H V D +SGS D L+LWDL + V + F G D++ + Sbjct: 337 HSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTVFAGSSCNDIVCT-----EQC 391 Query: 460 IVSASRDRTIKLWNTLGEC 516 ++S D+ I+ W+ EC Sbjct: 392 VMSGHFDKKIRFWDIRTEC 410 Score = 33.5 bits (75), Expect = 0.41 Identities = 17/51 (33%), Positives = 28/51 (54%), Gaps = 3/51 (5%) Frame = +1 Query: 403 FVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNTLG---ECKYTIGGDLGG 546 F H+ +V +V FS +R + + DR +KLW+ +G E K ++ G G Sbjct: 248 FDAHDGEVNAVRFSPGSRLLATGGMDRRVKLWDVIGNKCEAKGSLTGSNAG 298
>GBB_SOLTU (P93563) Guanine nucleotide-binding protein beta subunit| Length = 377 Score = 58.2 bits (139), Expect = 2e-08 Identities = 40/133 (30%), Positives = 70/133 (52%), Gaps = 2/133 (1%) Frame = +1 Query: 109 VMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 ++ GH V++ D +++SS D++ ++WD+T ++ +S +G F+ +GH Sbjct: 151 MLSGHKGYVSSCQYVPDEDTHLITSSGDQTCVLWDITTGLR-----TSVFGGEFQ--SGH 203 Query: 289 GHFVQDV-VLSSDGQFALSGSWDGELRLWDLSTGVTTRR-FVGHEKDVLSVAFSIDNRQI 462 V V + SS+ + +SGS D RLWD +R F GHE DV +V F D + Sbjct: 204 TADVLSVSISSSNPKLFVSGSCDTTARLWDTRVASRAQRTFHGHESDVNTVKFFPDGNRF 263 Query: 463 VSASRDRTIKLWN 501 + S D + +L++ Sbjct: 264 GTGSDDGSCRLFD 276 Score = 45.8 bits (107), Expect = 8e-05 Identities = 51/183 (27%), Positives = 78/183 (42%), Gaps = 46/183 (25%) Frame = +1 Query: 94 LVYAGVMRGHNDVVTAIA-TPIDNSPFIVSSSRDKSLLVWD-LTNP-------------- 225 LV +++GH V ++ TP N IVS+S+D L+VW+ LT+ Sbjct: 55 LVCCRILQGHTGKVYSLDWTPEKNR--IVSASQDGRLIVWNALTSQKTHAIKLPCAWVMT 112 Query: 226 -----------------------IQATQDTSSEYGVPFRRLTGHGHFVQDV-VLSSDGQF 333 + + D + V R L+GH +V + + Sbjct: 113 CAFSPSGQSVACGGLDSACSIFNLNSPIDKDGIHPVS-RMLSGHKGYVSSCQYVPDEDTH 171 Query: 334 ALSGSWDGELRLWDLSTGVTTRRF-----VGHEKDVLSVAFSIDNRQI-VSASRDRTIKL 495 ++ S D LWD++TG+ T F GH DVLSV+ S N ++ VS S D T +L Sbjct: 172 LITSSGDQTCVLWDITTGLRTSVFGGEFQSGHTADVLSVSISSSNPKLFVSGSCDTTARL 231 Query: 496 WNT 504 W+T Sbjct: 232 WDT 234 Score = 44.3 bits (103), Expect = 2e-04 Identities = 40/148 (27%), Positives = 58/148 (39%), Gaps = 5/148 (3%) Frame = +1 Query: 79 GAQESLVYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEY 258 G + S+ GH V +++ N VS S D + +WD +A Sbjct: 189 GLRTSVFGGEFQSGHTADVLSVSISSSNPKLFVSGSCDTTARLWDTRVASRAQ------- 241 Query: 259 GVPFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRF-----VGHEKD 423 R GH V V DG +GS DG RL+D+ TG + + G Sbjct: 242 ----RTFHGHESDVNTVKFFPDGNRFGTGSDDGSCRLFDIRTGHQLQVYNQPHGDGDIPH 297 Query: 424 VLSVAFSIDNRQIVSASRDRTIKLWNTL 507 V S+AFSI R + + +W+TL Sbjct: 298 VTSMAFSISGRLLFVGYSNGDCYVWDTL 325 Score = 29.6 bits (65), Expect = 5.9 Identities = 15/40 (37%), Positives = 23/40 (57%) Frame = +1 Query: 388 VTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNTL 507 V R GH V S+ ++ + +IVSAS+D + +WN L Sbjct: 56 VCCRILQGHTGKVYSLDWTPEKNRIVSASQDGRLIVWNAL 95
>SEL10_CAEEL (Q93794) F-box/WD-repeat protein sel-10 (Suppressor/enhancer of| lin-12) (Sel-10 protein) Length = 587 Score = 58.2 bits (139), Expect = 2e-08 Identities = 35/130 (26%), Positives = 57/130 (43%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 ++GH V +A +V+ SRD +L VWD+ + T HG Sbjct: 334 LQGHTSTVRCMAMA---GSILVTGSRDTTLRVWDVESGRHLA--------------TLHG 376 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSA 471 H + DG +SG +D +++W+ TG R GH V S+ F + + S Sbjct: 377 HHAAVRCVQFDGTTVVSGGYDFTVKIWNAHTGRCIRTLTGHNNRVYSLLFESERSIVCSG 436 Query: 472 SRDRTIKLWN 501 S D +I++W+ Sbjct: 437 SLDTSIRVWD 446 Score = 53.9 bits (128), Expect = 3e-07 Identities = 38/123 (30%), Positives = 56/123 (45%), Gaps = 1/123 (0%) Frame = +1 Query: 169 FIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGS 348 +IVS S D+++ VW + G L GH V+ + ++ G ++GS Sbjct: 310 YIVSGSTDRTVKVWSTVD------------GSLLHTLQGHTSTVRCMAMA--GSILVTGS 355 Query: 349 WDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNT-LGECKYT 525 D LR+WD+ +G GH V V F D +VS D T+K+WN G C T Sbjct: 356 RDTTLRVWDVESGRHLATLHGHHAAVRCVQF--DGTTVVSGGYDFTVKIWNAHTGRCIRT 413 Query: 526 IGG 534 + G Sbjct: 414 LTG 416 Score = 50.1 bits (118), Expect = 4e-06 Identities = 35/130 (26%), Positives = 56/130 (43%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 + GHN+ V ++ + S + S S D S+ VWD T P E L GH Sbjct: 414 LTGHNNRVYSLLFESERS-IVCSGSLDTSIRVWDFTRP---------EGQECVALLQGHT 463 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSA 471 + L G +S + D +R+WD+ G GH + S+ + + ++ Sbjct: 464 SLTSGMQLR--GNILVSCNADSHVRVWDIHEGTCVHMLSGHRSAITSLQW-FGRNMVATS 520 Query: 472 SRDRTIKLWN 501 S D T+KLW+ Sbjct: 521 SDDGTVKLWD 530 Score = 49.3 bits (116), Expect = 7e-06 Identities = 37/134 (27%), Positives = 61/134 (45%), Gaps = 1/134 (0%) Frame = +1 Query: 103 AGVMRGHND-VVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRL 279 + V+RGH D V+T + D +V+ S D +L VW + + G L Sbjct: 248 SAVLRGHEDHVITCMQIHDD---VLVTGSDDNTLKVWCI------------DKGEVMYTL 292 Query: 280 TGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQ 459 GH V +S G++ +SGS D +++W G GH V +A + Sbjct: 293 VGHTGGVWTSQISQCGRYIVSGSTDRTVKVWSTVDGSLLHTLQGHTSTVRCMAMA--GSI 350 Query: 460 IVSASRDRTIKLWN 501 +V+ SRD T+++W+ Sbjct: 351 LVTGSRDTTLRVWD 364 Score = 46.2 bits (108), Expect = 6e-05 Identities = 30/88 (34%), Positives = 45/88 (51%), Gaps = 2/88 (2%) Frame = +1 Query: 277 LTGH-GHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDN 453 L GH H + + + D ++GS D L++W + G VGH V + S Sbjct: 251 LRGHEDHVITCMQIHDD--VLVTGSDDNTLKVWCIDKGEVMYTLVGHTGGVWTSQISQCG 308 Query: 454 RQIVSASRDRTIKLWNTL-GECKYTIGG 534 R IVS S DRT+K+W+T+ G +T+ G Sbjct: 309 RYIVSGSTDRTVKVWSTVDGSLLHTLQG 336
>TAF73_SCHPO (O74319) Transcription initiation factor TFIID subunit taf73| (Transcription initiation factor TFIID 73 kDa subunit) (TAFII-73) Length = 642 Score = 58.2 bits (139), Expect = 2e-08 Identities = 38/131 (29%), Positives = 57/131 (43%), Gaps = 3/131 (2%) Frame = +1 Query: 118 GHNDVVTAIATPIDNSPF---IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 GHN A + SPF ++S D++ +WD+ E+ P R GH Sbjct: 443 GHN----APIWDVQFSPFGYYFATASHDQTARLWDV------------EHAAPLRVFVGH 486 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVS 468 + V V + + +GS D R+WD+ TG T R F H V ++ S D + S Sbjct: 487 QNDVDCVSFHPNAAYLATGSSDHTTRMWDVRTGGTVRVFNAHHSPVSALCMSADGLSLAS 546 Query: 469 ASRDRTIKLWN 501 A IK+W+ Sbjct: 547 ADESGIIKVWD 557 Score = 56.6 bits (135), Expect = 5e-08 Identities = 39/143 (27%), Positives = 62/143 (43%) Frame = +1 Query: 73 MAGAQESLVYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSS 252 + G+Q + + GH V ++ FI+S S D +W + T+ T Sbjct: 386 LVGSQNEPLQKSSLIGHTRPVFGVSIS-PQKEFILSCSEDGFTRLWS-----KDTKSTIV 439 Query: 253 EYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLS 432 +Y GH + DV S G + + S D RLWD+ R FVGH+ DV Sbjct: 440 KYA-------GHNAPIWDVQFSPFGYYFATASHDQTARLWDVEHAAPLRVFVGHQNDVDC 492 Query: 433 VAFSIDNRQIVSASRDRTIKLWN 501 V+F + + + S D T ++W+ Sbjct: 493 VSFHPNAAYLATGSSDHTTRMWD 515 Score = 52.8 bits (125), Expect = 7e-07 Identities = 34/131 (25%), Positives = 57/131 (43%) Frame = +1 Query: 109 VMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 V GH + V ++ N+ ++ + S D + +WD+ G R H Sbjct: 482 VFVGHQNDVDCVSFH-PNAAYLATGSSDHTTRMWDVRT------------GGTVRVFNAH 528 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVS 468 V + +S+DG S G +++WDL + FV H V S++FS DN+ +VS Sbjct: 529 HSPVSALCMSADGLSLASADESGIIKVWDLRSSNQHVSFVKHSSIVYSLSFSYDNKILVS 588 Query: 469 ASRDRTIKLWN 501 D + W+ Sbjct: 589 GGADTDVNFWD 599
>FBW1A_HUMAN (Q9Y297) F-box/WD-repeat protein 1A (F-box and WD-repeats protein| beta-TrCP) (E3RSIkappaB) (pIkappaBalpha-E3 receptor subunit) Length = 605 Score = 58.2 bits (139), Expect = 2e-08 Identities = 41/131 (31%), Positives = 65/131 (49%) Frame = +1 Query: 109 VMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 V+ GH V + + +IVS+S D+++ VW+ + + E+ R L GH Sbjct: 421 VLVGHRAAVNVVDF---DDKYIVSASGDRTIKVWNTS---------TCEF---VRTLNGH 465 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVS 468 + L + +SGS D +RLWD+ G R GHE+ V + F DN++IVS Sbjct: 466 KRGI--ACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRF--DNKRIVS 521 Query: 469 ASRDRTIKLWN 501 + D IK+W+ Sbjct: 522 GAYDGKIKVWD 532 Score = 53.5 bits (127), Expect = 4e-07 Identities = 36/119 (30%), Positives = 60/119 (50%) Frame = +1 Query: 172 IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSW 351 IVS RD ++ +WD N ++ R LTGH V + L D + ++GS Sbjct: 316 IVSGLRDNTIKIWD-KNTLECK-----------RILTGHTGSV--LCLQYDERVIITGSS 361 Query: 352 DGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNTLGECKYTI 528 D +R+WD++TG + H + VL + F +N +V+ S+DR+I +W+ T+ Sbjct: 362 DSTVRVWDVNTGEMLNTLIHHCEAVLHLRF--NNGMMVTCSKDRSIAVWDMASPTDITL 418 Score = 52.4 bits (124), Expect = 9e-07 Identities = 37/123 (30%), Positives = 58/123 (47%), Gaps = 9/123 (7%) Frame = +1 Query: 172 IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSW 351 +VS S D ++ +WD+ E G R L GH V+ + D + +SG++ Sbjct: 479 VVSGSSDNTIRLWDI------------ECGACLRVLEGHEELVR--CIRFDNKRIVSGAY 524 Query: 352 DGELRLWDLSTG---------VTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNT 504 DG++++WDL + R V H V + F D QIVS+S D TI +W+ Sbjct: 525 DGKIKVWDLVAALDPRAPAGTLCLRTLVEHSGRVFRLQF--DEFQIVSSSHDDTILIWDF 582 Query: 505 LGE 513 L + Sbjct: 583 LND 585 Score = 41.6 bits (96), Expect = 0.002 Identities = 21/63 (33%), Positives = 34/63 (53%) Frame = +1 Query: 313 LSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIK 492 L D Q +SG D +++WD +T R GH VL + + D R I++ S D T++ Sbjct: 309 LQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQY--DERVIITGSSDSTVR 366 Query: 493 LWN 501 +W+ Sbjct: 367 VWD 369
>U3IP2_MOUSE (Q91WM3) U3 small nucleolar RNA-interacting protein 2 (U3 small| nucleolar ribonucleoproptein-associated 55-kDa protein) (U3 snoRNP-associated 55-kDa protein) (U3-55K) Length = 475 Score = 58.2 bits (139), Expect = 2e-08 Identities = 37/132 (28%), Positives = 65/132 (49%), Gaps = 1/132 (0%) Frame = +1 Query: 109 VMRGHNDVVTAIA-TPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTG 285 V+RGH +T + TP D + F S+++D +++ W + + ++ G + G Sbjct: 141 VLRGHQLSITCLVITPDDLAIF--SAAKDCTIIKWSVETGRKLHVIPRAKKGAQGQP-AG 197 Query: 286 HGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIV 465 H V + +SSDG++ SG + +W+ + F GH V +AF Q+ Sbjct: 198 HSSHVLCMAISSDGKYLASGDRSKLILIWEAQSCQHLYTFTGHRDAVSGLAFRKGTHQLY 257 Query: 466 SASRDRTIKLWN 501 S S DR++K+WN Sbjct: 258 STSHDRSVKVWN 269 Score = 40.0 bits (92), Expect = 0.004 Identities = 39/175 (22%), Positives = 64/175 (36%) Frame = +1 Query: 19 RRLHRTPRKP*RSLRHTTMAGAQESLVYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKS 198 R+LH PR GAQ G GH+ V +A D ++ S R K Sbjct: 179 RKLHVIPR---------AKKGAQ------GQPAGHSSHVLCMAISSDGK-YLASGDRSKL 222 Query: 199 LLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDL 378 +L+W+ Q+ Q + TGH V + S S D +++W+ Sbjct: 223 ILIWEA----QSCQHLYT--------FTGHRDAVSGLAFRKGTHQLYSTSHDRSVKVWNA 270 Query: 379 STGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNTLGECKYTIGGDLG 543 + GH+ V ++ + + RD T+++W E + G G Sbjct: 271 AENSYVETLFGHQDAVAALDALSRECCVTAGGRDGTVRVWKIPEESQLVFYGHQG 325 Score = 33.1 bits (74), Expect = 0.54 Identities = 24/87 (27%), Positives = 37/87 (42%), Gaps = 11/87 (12%) Frame = +1 Query: 271 RRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTG----VTTR-------RFVGHE 417 R L GH + +V++ D S + D + W + TG V R + GH Sbjct: 140 RVLRGHQLSITCLVITPDDLAIFSAAKDCTIIKWSVETGRKLHVIPRAKKGAQGQPAGHS 199 Query: 418 KDVLSVAFSIDNRQIVSASRDRTIKLW 498 VL +A S D + + S R + I +W Sbjct: 200 SHVLCMAISSDGKYLASGDRSKLILIW 226 Score = 29.6 bits (65), Expect = 5.9 Identities = 30/144 (20%), Positives = 55/144 (38%), Gaps = 11/144 (7%) Frame = +1 Query: 100 YAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRL 279 Y + GH D V A+ + + + RD ++ VW + Q Sbjct: 275 YVETLFGHQDAVAALDA-LSRECCVTAGGRDGTVRVWKIPEESQLV-------------F 320 Query: 280 TGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLST-----------GVTTRRFVGHEKDV 426 GH + + L ++ + +SG+ DG + LW LS G+ + V Sbjct: 321 YGHQGSIDCIHLINE-EHMVSGADDGSVALWGLSKKRPLALQREAHGLHGEPGLEQPFWV 379 Query: 427 LSVAFSIDNRQIVSASRDRTIKLW 498 SVA ++ + + S + ++LW Sbjct: 380 SSVAALLNTDLVATGSHNARVRLW 403
>YK16_YEAST (P36130) Hypothetical 74.7 kDa Trp-Asp repeats-containing protein| in DAL80-GAP1 intergenic region Length = 659 Score = 58.2 bits (139), Expect = 2e-08 Identities = 41/138 (29%), Positives = 64/138 (46%), Gaps = 11/138 (7%) Frame = +1 Query: 121 HNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQ------DTSSEYGVPFRRLT 282 H D +TA++ +S +VS SRDK + WDLT Q T S+ +P R L Sbjct: 439 HKDEITALSF---DSEALVSGSRDKKIFHWDLTTGKCIQQLDLIFTPTHSDIKMPARSLN 495 Query: 283 GHGHFVQDVV-----LSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSI 447 + L +G+ DG +RLWDL G R GH + S+ F Sbjct: 496 NGACLLGTEAPMIGALQCYNSALATGTKDGIVRLWDLRVGKPVRLLEGHTDGITSLKF-- 553 Query: 448 DNRQIVSASRDRTIKLWN 501 D+ ++V+ S D ++++W+ Sbjct: 554 DSEKLVTGSMDNSVRIWD 571 Score = 41.6 bits (96), Expect = 0.002 Identities = 41/153 (26%), Positives = 63/153 (41%), Gaps = 21/153 (13%) Frame = +1 Query: 121 HNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFV 300 H + +TA+ SS +D+ + VWDL + IQ + L GH V Sbjct: 334 HGNSITALDFDTPWGTLCSSSYQDRIVKVWDLNHGIQVGE------------LPGHLATV 381 Query: 301 QDVVLSSDG-QFALSGSWDGELRLWDLSTG-----------------VT--TRRFVGHEK 420 + + ++GS D L+LWDL+ VT F H+ Sbjct: 382 NCMQIDKKNYNMLITGSKDATLKLWDLNLSREIYLDHSPLKEKTEEIVTPCIHNFELHKD 441 Query: 421 DVLSVAFSIDNRQIVSASRDRTIKLWN-TLGEC 516 ++ A S D+ +VS SRD+ I W+ T G+C Sbjct: 442 EI--TALSFDSEALVSGSRDKKIFHWDLTTGKC 472 Score = 37.7 bits (86), Expect = 0.022 Identities = 34/133 (25%), Positives = 56/133 (42%), Gaps = 14/133 (10%) Frame = +1 Query: 97 VYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRR 276 + G + GH V + N +++ S+D +L +WDL + D S P + Sbjct: 369 IQVGELPGHLATVNCMQIDKKNYNMLITGSKDATLKLWDLNLSREIYLDHS-----PLKE 423 Query: 277 LTG-------HG---HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRR----FVGH 414 T H H + LS D + +SGS D ++ WDL+TG ++ F Sbjct: 424 KTEEIVTPCIHNFELHKDEITALSFDSEALVSGSRDKKIFHWDLTTGKCIQQLDLIFTPT 483 Query: 415 EKDVLSVAFSIDN 453 D+ A S++N Sbjct: 484 HSDIKMPARSLNN 496 Score = 34.3 bits (77), Expect = 0.24 Identities = 26/110 (23%), Positives = 49/110 (44%) Frame = +1 Query: 172 IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSW 351 + + ++D + +WDL G P R L GH + L D + ++GS Sbjct: 518 LATGTKDGIVRLWDL------------RVGKPVRLLEGHTDGITS--LKFDSEKLVTGSM 563 Query: 352 DGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN 501 D +R+WDL T + + ++ V S+ F D + I + + + ++N Sbjct: 564 DNSVRIWDLRTS-SILDVIAYDLPVSSLDF--DGKLITVGANEGGVNVFN 610
>WS17_SCHMA (Q26544) WD-repeat protein SL1-17| Length = 301 Score = 57.8 bits (138), Expect = 2e-08 Identities = 35/114 (30%), Positives = 56/114 (49%) Frame = +1 Query: 160 NSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFAL 339 N +I++ S D L+ W+ TN S+ ++ GH V V ++S G A Sbjct: 28 NKQYIITGSLDNGLIAWEWTN---------SQLKCLYQ-FEGHRLGVISVDINSTGTLAA 77 Query: 340 SGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN 501 S S D ++ LWDL TG T+ + G D ++AFS D+R + + S + + N Sbjct: 78 SSSLDSQILLWDLETGRLTKTYDGDPADTWTIAFSPDSRFLATGSHTGCVNMIN 131 Score = 50.8 bits (120), Expect = 2e-06 Identities = 27/76 (35%), Positives = 46/76 (60%), Gaps = 1/76 (1%) Frame = +1 Query: 277 LTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTG-VTTRRFVGHEKDVLSVAFSIDN 453 L GH V+ V S DG+ S S D +++++D+ G + GH+ V+SV F+ DN Sbjct: 182 LDGHATPVRSVSFSPDGRLLASASDDKQIKVFDVRDGRLVIPSLNGHKGWVVSVDFASDN 241 Query: 454 RQIVSASRDRTIKLWN 501 R +V+AS D ++++W+ Sbjct: 242 RHLVTASTDCSVRIWD 257 Score = 47.0 bits (110), Expect = 4e-05 Identities = 34/124 (27%), Positives = 57/124 (45%), Gaps = 6/124 (4%) Frame = +1 Query: 145 ATPIDNSPF------IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQD 306 ATP+ + F + S+S DK + V+D+ + +P L GH +V Sbjct: 186 ATPVRSVSFSPDGRLLASASDDKQIKVFDVRD---------GRLVIP--SLNGHKGWVVS 234 Query: 307 VVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRT 486 V +SD + ++ S D +R+WDL++ F HE V +S I+S DR+ Sbjct: 235 VDFASDNRHLVTASTDCSVRIWDLASKEEKHCFNTHEDQVWCARYSPQGNNIISVGDDRS 294 Query: 487 IKLW 498 I ++ Sbjct: 295 IMIY 298
>TBL1X_HUMAN (O60907) F-box-like/WD-repeat protein TBL1X (Transducin beta-like| 1X protein) (Transducin-beta-like 1, X-linked) (SMAP55) Length = 526 Score = 57.8 bits (138), Expect = 2e-08 Identities = 40/139 (28%), Positives = 59/139 (42%), Gaps = 9/139 (6%) Frame = +1 Query: 115 RGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGH 294 +GH + V AI + + S S D +L +W S + V L H Sbjct: 358 QGHTNEVNAIKWD-PSGMLLASCSDDMTLKIW------------SMKQEVCIHDLQAHNK 404 Query: 295 FVQDVVLSSDGQ---------FALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSI 447 + + S G S S+D +RLWD+ GV T H++ V SVAFS Sbjct: 405 EIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDIERGVCTHTLTKHQEPVYSVAFSP 464 Query: 448 DNRQIVSASRDRTIKLWNT 504 D + + S S D+ + +WNT Sbjct: 465 DGKYLASGSFDKCVHIWNT 483 Score = 40.0 bits (92), Expect = 0.004 Identities = 25/98 (25%), Positives = 42/98 (42%), Gaps = 10/98 (10%) Frame = +1 Query: 265 PFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFS 444 P + GH + V + G S S D L++W + V H K++ ++ +S Sbjct: 353 PVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWS 412 Query: 445 ---------IDNRQIVSASRDRTIKLWN-TLGECKYTI 528 N + SAS D T++LW+ G C +T+ Sbjct: 413 PTGPATSNPNSNIMLASASFDSTVRLWDIERGVCTHTL 450 Score = 39.3 bits (90), Expect = 0.007 Identities = 28/93 (30%), Positives = 43/93 (46%), Gaps = 1/93 (1%) Frame = +1 Query: 136 TAIATPIDNSPFIVSS-SRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVV 312 T AT NS +++S S D ++ +WD+ E GV LT H V V Sbjct: 414 TGPATSNPNSNIMLASASFDSTVRLWDI------------ERGVCTHTLTKHQEPVYSVA 461 Query: 313 LSSDGQFALSGSWDGELRLWDLSTGVTTRRFVG 411 S DG++ SGS+D + +W+ +G + G Sbjct: 462 FSPDGKYLASGSFDKCVHIWNTQSGNLVHSYRG 494 Score = 31.6 bits (70), Expect = 1.6 Identities = 27/103 (26%), Positives = 42/103 (40%), Gaps = 14/103 (13%) Frame = +1 Query: 277 LTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDL-------STGVTTRRFV---GHE--- 417 L GH V + SGS D R+W+L ST + R + GH+ Sbjct: 177 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPS 236 Query: 418 -KDVLSVAFSIDNRQIVSASRDRTIKLWNTLGECKYTIGGDLG 543 KDV S+ ++ + + + S D ++W G T+G G Sbjct: 237 NKDVTSLDWNTNGTLLATGSYDGFARIWTEDGNLASTLGQHKG 279
>GBB1_BRARE (Q6PH57) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 340 Score = 57.8 bits (138), Expect = 2e-08 Identities = 35/130 (26%), Positives = 59/130 (45%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 + GH ++ DN IV+SS D + +WD+ Q T GH Sbjct: 139 LAGHTGYLSCCRFLDDNQ--IVTSSGDTTCALWDIETGQQTTT------------FAGHT 184 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSA 471 V + L+ D + +SG+ D +LWD+ G+ + F GHE D+ ++ F + + Sbjct: 185 GDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATG 244 Query: 472 SRDRTIKLWN 501 S D T +L++ Sbjct: 245 SDDATCRLFD 254 Score = 35.0 bits (79), Expect = 0.14 Identities = 17/68 (25%), Positives = 28/68 (41%) Frame = +1 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASR 477 + V S G+ L+G D +WD GH+ V + + D + + S Sbjct: 273 ITSVAFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSW 332 Query: 478 DRTIKLWN 501 D +K+WN Sbjct: 333 DSFLKIWN 340 Score = 33.1 bits (74), Expect = 0.54 Identities = 25/99 (25%), Positives = 46/99 (46%), Gaps = 2/99 (2%) Frame = +1 Query: 85 QESLVYAGVMRGHNDVVTAIATPI--DNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEY 258 QE +VY+ H++++ I + + +++ D + VWD +A Sbjct: 259 QELMVYS-----HDNIICGITSVAFSKSGRLLLAGYDDFNCNVWDALKADRA-------- 305 Query: 259 GVPFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWD 375 GV L GH + V + ++ DG +GSWD L++W+ Sbjct: 306 GV----LAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
>KMHB_DICDI (P90648) Myosin heavy chain kinase B (EC 2.7.11.7) (MHCK B)| Length = 732 Score = 57.4 bits (137), Expect = 3e-08 Identities = 43/142 (30%), Positives = 66/142 (46%), Gaps = 1/142 (0%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 + GH+ V + N ++ S S DK++ VWDL + +Y L H Sbjct: 538 LEGHDKPVHTVLL---NDKYLFSGSSDKTIKVWDL-------KTLECKY-----TLESHA 582 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSA 471 V+ + +S GQ+ SGS D +++WDL T GH K V ++ I + S Sbjct: 583 RAVKTLCIS--GQYLFSGSNDKTIKVWDLKTFRCNYTLKGHTKWVTTIC--ILGTNLYSG 638 Query: 472 SRDRTIKLWNTLG-ECKYTIGG 534 S D+TI++WN EC T+ G Sbjct: 639 SYDKTIRVWNLKSLECSATLRG 660 Score = 49.7 bits (117), Expect = 6e-06 Identities = 37/130 (28%), Positives = 59/130 (45%), Gaps = 1/130 (0%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTN-PIQATQDTSSEYGVPFRRLTGH 288 ++GH VT I N + S S DK++ VW+L + AT L GH Sbjct: 618 LKGHTKWVTTICILGTN---LYSGSYDKTIRVWNLKSLECSAT-------------LRGH 661 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVS 468 +V+ +V+ F S D +++WDL T GH V +A D + ++S Sbjct: 662 DRWVEHMVICDKLLFTASD--DNTIKIWDLETLRCNTTLEGHNATVQCLAVWEDKKCVIS 719 Query: 469 ASRDRTIKLW 498 S D++I++W Sbjct: 720 CSHDQSIRVW 729 Score = 48.1 bits (113), Expect = 2e-05 Identities = 31/86 (36%), Positives = 49/86 (56%), Gaps = 2/86 (2%) Frame = +1 Query: 277 LTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNR 456 L GH V+ + + Q+ SGS D +++WDL GH+K V +V ++++ Sbjct: 498 LKGHEGPVESICYND--QYLFSGSSDHSIKVWDLKKLRCIFTLEGHDKPVHTVL--LNDK 553 Query: 457 QIVSASRDRTIKLWN--TLGECKYTI 528 + S S D+TIK+W+ TL ECKYT+ Sbjct: 554 YLFSGSSDKTIKVWDLKTL-ECKYTL 578
>TBL1R_MOUSE (Q8BHJ5) F-box-like/WD-repeat protein TBL1XR1 (Transducin beta-like| 1X-related protein 1) (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1) (TBL1-related protein 1) Length = 514 Score = 57.4 bits (137), Expect = 3e-08 Identities = 42/133 (31%), Positives = 61/133 (45%), Gaps = 3/133 (2%) Frame = +1 Query: 115 RGHNDVVTAIA-TPIDNSPFIVSSSRDKSLLVWDLT--NPIQATQDTSSEYGVPFRRLTG 285 +GH + V AI P N + S S D +L +W + N + Q + E TG Sbjct: 346 QGHTNEVNAIKWDPTGN--LLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWSPTG 403 Query: 286 HGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIV 465 G + L S S+D +RLWD+ G+ H++ V SVAFS D R + Sbjct: 404 PGTNNPNANL-----MLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLA 458 Query: 466 SASRDRTIKLWNT 504 S S D+ + +WNT Sbjct: 459 SGSFDKCVHIWNT 471 Score = 41.2 bits (95), Expect = 0.002 Identities = 28/108 (25%), Positives = 47/108 (43%), Gaps = 8/108 (7%) Frame = +1 Query: 112 MRGHNDVVTAI----ATPIDNSP----FIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVP 267 ++ HN + I P N+P + S+S D ++ +WD+ + G+ Sbjct: 387 LQAHNKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVRLWDV------------DRGIC 434 Query: 268 FRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVG 411 LT H V V S DG++ SGS+D + +W+ TG + G Sbjct: 435 IHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSYRG 482 Score = 39.3 bits (90), Expect = 0.007 Identities = 38/148 (25%), Positives = 62/148 (41%), Gaps = 9/148 (6%) Frame = +1 Query: 103 AGVMRGHNDVVTAIA-TPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRL 279 A V+RGH V A P+ S + S S D + +W+L+ TS + R Sbjct: 162 AVVLRGHESEVFICAWNPV--SDLLASGSGDSTARIWNLSE-----NSTSGPTQLVLRHC 214 Query: 280 TGHG-------HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVA 438 G V + +S+G +GS+DG R+W G H+ + ++ Sbjct: 215 IREGGQDVPSNKDVTSLDWNSEGTLLATGSYDGFARIW-TKDGNLASTLGQHKGPIFALK 273 Query: 439 FSIDNRQIVSASRDRTIKLWNT-LGECK 519 ++ I+SA D+T +W+ GE K Sbjct: 274 WNKKGNFILSAGVDKTTIIWDAHTGEAK 301 Score = 37.4 bits (85), Expect = 0.028 Identities = 24/98 (24%), Positives = 41/98 (41%), Gaps = 10/98 (10%) Frame = +1 Query: 265 PFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFS 444 P + GH + V + G S S D L++W + H K++ ++ +S Sbjct: 341 PIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWS 400 Query: 445 ID---------NRQIVSASRDRTIKLWNT-LGECKYTI 528 N + SAS D T++LW+ G C +T+ Sbjct: 401 PTGPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTL 438 Score = 30.8 bits (68), Expect = 2.7 Identities = 26/103 (25%), Positives = 40/103 (38%), Gaps = 14/103 (13%) Frame = +1 Query: 277 LTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVT---TRRFVGH----------- 414 L GH V + SGS D R+W+LS T T+ + H Sbjct: 165 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLSENSTSGPTQLVLRHCIREGGQDVPS 224 Query: 415 EKDVLSVAFSIDNRQIVSASRDRTIKLWNTLGECKYTIGGDLG 543 KDV S+ ++ + + + S D ++W G T+G G Sbjct: 225 NKDVTSLDWNSEGTLLATGSYDGFARIWTKDGNLASTLGQHKG 267 Score = 29.3 bits (64), Expect = 7.8 Identities = 18/55 (32%), Positives = 22/55 (40%) Frame = +1 Query: 325 GQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTI 489 G F LS D +WD TG ++F H L V + N S S D I Sbjct: 278 GNFILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQ-SNNTFASCSTDMCI 331
>TBL1R_HUMAN (Q9BZK7) F-box-like/WD-repeat protein TBL1XR1 (Transducin beta-like| 1X-related protein 1) (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1) (TBL1-related protein 1) Length = 514 Score = 57.4 bits (137), Expect = 3e-08 Identities = 42/133 (31%), Positives = 61/133 (45%), Gaps = 3/133 (2%) Frame = +1 Query: 115 RGHNDVVTAIA-TPIDNSPFIVSSSRDKSLLVWDLT--NPIQATQDTSSEYGVPFRRLTG 285 +GH + V AI P N + S S D +L +W + N + Q + E TG Sbjct: 346 QGHTNEVNAIKWDPTGN--LLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWSPTG 403 Query: 286 HGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIV 465 G + L S S+D +RLWD+ G+ H++ V SVAFS D R + Sbjct: 404 PGTNNPNANL-----MLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLA 458 Query: 466 SASRDRTIKLWNT 504 S S D+ + +WNT Sbjct: 459 SGSFDKCVHIWNT 471 Score = 41.2 bits (95), Expect = 0.002 Identities = 28/108 (25%), Positives = 47/108 (43%), Gaps = 8/108 (7%) Frame = +1 Query: 112 MRGHNDVVTAI----ATPIDNSP----FIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVP 267 ++ HN + I P N+P + S+S D ++ +WD+ + G+ Sbjct: 387 LQAHNKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVRLWDV------------DRGIC 434 Query: 268 FRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVG 411 LT H V V S DG++ SGS+D + +W+ TG + G Sbjct: 435 IHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSYRG 482 Score = 39.7 bits (91), Expect = 0.006 Identities = 38/148 (25%), Positives = 62/148 (41%), Gaps = 9/148 (6%) Frame = +1 Query: 103 AGVMRGHNDVVTAIA-TPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRL 279 A V+RGH V A P+ S + S S D + +W+L+ TS + R Sbjct: 162 AVVLRGHESEVFICAWNPV--SDLLASGSGDSTARIWNLSE-----NSTSGSTQLVLRHC 214 Query: 280 TGHG-------HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVA 438 G V + +S+G +GS+DG R+W G H+ + ++ Sbjct: 215 IREGGQDVPSNKDVTSLDWNSEGTLLATGSYDGFARIW-TKDGNLASTLGQHKGPIFALK 273 Query: 439 FSIDNRQIVSASRDRTIKLWNT-LGECK 519 ++ I+SA D+T +W+ GE K Sbjct: 274 WNKKGNFILSAGVDKTTIIWDAHTGEAK 301 Score = 37.4 bits (85), Expect = 0.028 Identities = 24/98 (24%), Positives = 41/98 (41%), Gaps = 10/98 (10%) Frame = +1 Query: 265 PFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFS 444 P + GH + V + G S S D L++W + H K++ ++ +S Sbjct: 341 PIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWS 400 Query: 445 ID---------NRQIVSASRDRTIKLWNT-LGECKYTI 528 N + SAS D T++LW+ G C +T+ Sbjct: 401 PTGPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTL 438 Score = 31.2 bits (69), Expect = 2.0 Identities = 26/103 (25%), Positives = 41/103 (39%), Gaps = 14/103 (13%) Frame = +1 Query: 277 LTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLS---TGVTTRRFVGH----------- 414 L GH V + SGS D R+W+LS T +T+ + H Sbjct: 165 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVPS 224 Query: 415 EKDVLSVAFSIDNRQIVSASRDRTIKLWNTLGECKYTIGGDLG 543 KDV S+ ++ + + + S D ++W G T+G G Sbjct: 225 NKDVTSLDWNSEGTLLATGSYDGFARIWTKDGNLASTLGQHKG 267 Score = 29.3 bits (64), Expect = 7.8 Identities = 18/55 (32%), Positives = 22/55 (40%) Frame = +1 Query: 325 GQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTI 489 G F LS D +WD TG ++F H L V + N S S D I Sbjct: 278 GNFILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQ-SNNTFASCSTDMCI 331
>APAF_RAT (Q9EPV5) Apoptotic protease-activating factor 1 (Apaf-1)| Length = 1249 Score = 57.4 bits (137), Expect = 3e-08 Identities = 42/128 (32%), Positives = 60/128 (46%) Frame = +1 Query: 118 GHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHF 297 GH V I D ++SSS D + VW+ + EY L H Sbjct: 1001 GHKKAVRHIQFTADGKT-LISSSEDSVIQVWNWQ---------TEEYVF----LQAHQET 1046 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASR 477 V+D L D + LS S+DG +++W++ TG R F H+ VLS A S D + S S Sbjct: 1047 VKDFRLLRDSRL-LSWSFDGTVKVWNVITGRIERDFTCHQGTVLSCAISSDATKFSSTSA 1105 Query: 478 DRTIKLWN 501 D+T K+W+ Sbjct: 1106 DKTAKIWS 1113 Score = 53.1 bits (126), Expect = 5e-07 Identities = 40/131 (30%), Positives = 57/131 (43%), Gaps = 1/131 (0%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDL-TNPIQATQDTSSEYGVPFRRLTGH 288 ++ H D V A D+S +I + S DK + +WD T + T + SE Sbjct: 653 IKAHEDEVLCCAFSSDDS-YIATCSVDKKVKIWDSGTGKLVHTYEEHSEQ-------VNC 704 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVS 468 HF S+ +GS D L+LWDL+ GH V FS D+ + S Sbjct: 705 CHFTN----KSNHLLLATGSNDSFLKLWDLNQKECRNTMFGHTNSVTHCRFSPDDELLAS 760 Query: 469 ASRDRTIKLWN 501 S D T+KLW+ Sbjct: 761 CSADGTLKLWD 771 Score = 45.4 bits (106), Expect = 1e-04 Identities = 42/145 (28%), Positives = 58/145 (40%), Gaps = 10/145 (6%) Frame = +1 Query: 121 HNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFV 300 H V + A D + F S+S DK+ +W S E P L GH V Sbjct: 1084 HQGTVLSCAISSDATKFS-STSADKTAKIW------------SFELPSPLHELKGHNSCV 1130 Query: 301 QDVVLSSDGQFALSGSWDGELRLWDLSTG---------VTTRRFVGHEKDVLSVAFSIDN 453 + S DG +G +GE+R+W++S G H V V FS D Sbjct: 1131 RCSAFSLDGILLATGDDNGEIRIWNVSDGQLLHLCAPISIEEGTATHGGWVTDVCFSPDR 1190 Query: 454 RQIVSASRDRTIKLWNTL-GECKYT 525 + +VSA +K WN + GE T Sbjct: 1191 KMLVSAG--GYLKWWNVVTGESSQT 1213 Score = 43.1 bits (100), Expect = 5e-04 Identities = 24/73 (32%), Positives = 35/73 (47%) Frame = +1 Query: 286 HGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIV 465 H V S DGQ S D L+++ TG HE +VL AFS D+ I Sbjct: 614 HTDAVYHACFSQDGQRIASCGADKTLQVFKAETGEKLLDIKAHEDEVLCCAFSSDDSYIA 673 Query: 466 SASRDRTIKLWNT 504 + S D+ +K+W++ Sbjct: 674 TCSVDKKVKIWDS 686 Score = 41.6 bits (96), Expect = 0.002 Identities = 38/145 (26%), Positives = 59/145 (40%), Gaps = 3/145 (2%) Frame = +1 Query: 109 VMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 V+R H D V D I S DK+L V+ +E G + H Sbjct: 610 VVRPHTDAVYHACFSQDGQR-IASCGADKTLQVF------------KAETGEKLLDIKAH 656 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVS 468 V SSD + + S D ++++WD TG + H + V F+ + ++ Sbjct: 657 EDEVLCCAFSSDDSYIATCSVDKKVKIWDSGTGKLVHTYEEHSEQVNCCHFTNKSNHLLL 716 Query: 469 A--SRDRTIKLWN-TLGECKYTIGG 534 A S D +KLW+ EC+ T+ G Sbjct: 717 ATGSNDSFLKLWDLNQKECRNTMFG 741 Score = 40.0 bits (92), Expect = 0.004 Identities = 35/163 (21%), Positives = 66/163 (40%), Gaps = 25/163 (15%) Frame = +1 Query: 88 ESLVYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDT-SSEYGV 264 +S V RGH V + D S F+ +S D+++ VW+ + + E V Sbjct: 870 DSRVKVADCRGHLSWVHGVMFSPDGSSFLTASD-DQTIRVWETRKVCKNSAIVLKQEIDV 928 Query: 265 PFRR-------------------LTGHGHFVQDV-----VLSSDGQFALSGSWDGELRLW 372 F+ TG ++ + LS ++ G +G +++ Sbjct: 929 VFQENEMMVLAVDNIRGLQLIAGKTGQIDYLPEAQVSCCCLSPHLEYVAFGDEEGAIKII 988 Query: 373 DLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN 501 +L +GH+K V + F+ D + ++S+S D I++WN Sbjct: 989 ELPNNRVFSSGIGHKKAVRHIQFTADGKTLISSSEDSVIQVWN 1031 Score = 40.0 bits (92), Expect = 0.004 Identities = 25/80 (31%), Positives = 36/80 (45%) Frame = +1 Query: 280 TGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQ 459 TGH +Q S A+ + LW++ + V GH V V FS D Sbjct: 837 TGHHSTIQYCDFSPYDHLAVIALSQYCVELWNIDSRVKVADCRGHLSWVHGVMFSPDGSS 896 Query: 460 IVSASRDRTIKLWNTLGECK 519 ++AS D+TI++W T CK Sbjct: 897 FLTASDDQTIRVWETRKVCK 916 Score = 35.8 bits (81), Expect = 0.083 Identities = 22/78 (28%), Positives = 41/78 (52%), Gaps = 3/78 (3%) Frame = +1 Query: 283 GHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFV---GHEKDVLSVAFSIDN 453 GH V+ + ++DG+ +S S D +++W+ T +V H++ V D+ Sbjct: 1001 GHKKAVRHIQFTADGKTLISSSEDSVIQVWNWQT----EEYVFLQAHQETVKDFRLLRDS 1056 Query: 454 RQIVSASRDRTIKLWNTL 507 R ++S S D T+K+WN + Sbjct: 1057 R-LLSWSFDGTVKVWNVI 1073 Score = 34.7 bits (78), Expect = 0.18 Identities = 30/125 (24%), Positives = 54/125 (43%), Gaps = 13/125 (10%) Frame = +1 Query: 160 NSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFAL 339 N + + S D L +WDL + ++T + GH + V S D + Sbjct: 712 NHLLLATGSNDSFLKLWDLNQ--KECRNT----------MFGHTNSVTHCRFSPDDELLA 759 Query: 340 SGSWDGELRLWDLST-----GVTTRRFVGHEKD--------VLSVAFSIDNRQIVSASRD 480 S S DG L+LWD+ + + +RF +D V ++S D +I+ A+++ Sbjct: 760 SCSADGTLKLWDVRSANEKKSINVKRFFLSSEDPPEDVEVIVKCCSWSADGDRIIVAAKN 819 Query: 481 RTIKL 495 + + L Sbjct: 820 KVLLL 824
>PRP4_HUMAN (O43172) U4/U6 small nuclear ribonucleoprotein Prp4 (U4/U6 snRNP 60| kDa protein) (WD splicing factor Prp4) (hPrp4) Length = 522 Score = 57.0 bits (136), Expect = 3e-08 Identities = 37/121 (30%), Positives = 56/121 (46%), Gaps = 1/121 (0%) Frame = +1 Query: 169 FIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGS 348 F+ ++ D+S +WDL +A ++ + GH V D+ DG A +G Sbjct: 337 FLGTTCYDRSWRLWDL----EAQEEILHQ--------EGHSMGVYDIAFHQDGSLAGTGG 384 Query: 349 WDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN-TLGECKYT 525 D R+WDL TG GH K++ + FS + I + S D T K+W+ C YT Sbjct: 385 LDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYT 444 Query: 526 I 528 I Sbjct: 445 I 445 Score = 48.9 bits (115), Expect = 9e-06 Identities = 33/114 (28%), Positives = 48/114 (42%), Gaps = 1/114 (0%) Frame = +1 Query: 160 NSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSS-DGQFA 336 N I + S D + VWDL + Y +P H + V V G F Sbjct: 418 NGYHIATGSGDNTCKVWDL-------RQRRCVYTIP-----AHQNLVTGVKFEPIHGNFL 465 Query: 337 LSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLW 498 L+G++D ++W + GHE V+ + S D + I + S DRT KLW Sbjct: 466 LTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLW 519 Score = 38.9 bits (89), Expect = 0.010 Identities = 38/151 (25%), Positives = 57/151 (37%), Gaps = 8/151 (5%) Frame = +1 Query: 112 MRGHNDVVTAIA----TPIDNSPF---IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPF 270 +RGHN V AI + + P + S + D S+ +W L + P Sbjct: 269 LRGHNTNVGAIVFHPKSTVSLDPKDVNLASCAADGSVKLWSLDSD------------EPV 316 Query: 271 RRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSID 450 + GH V V+ G+F + +D RLWDL GH V +AF D Sbjct: 317 ADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQD 376 Query: 451 NRQIVSASRDRTIKLWN-TLGECKYTIGGDL 540 + D ++W+ G C + G L Sbjct: 377 GSLAGTGGLDAFGRVWDLRTGRCIMFLEGHL 407 Score = 35.4 bits (80), Expect = 0.11 Identities = 37/144 (25%), Positives = 54/144 (37%), Gaps = 1/144 (0%) Frame = +1 Query: 82 AQESLVYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYG 261 AQE +++ GH+ V IA D S + D VWDL G Sbjct: 354 AQEEILH---QEGHSMGVYDIAFHQDGS-LAGTGGLDAFGRVWDLRT------------G 397 Query: 262 VPFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAF 441 L GH + + S +G +GS D ++WDL H+ V V F Sbjct: 398 RCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKF 457 Query: 442 S-IDNRQIVSASRDRTIKLWNTLG 510 I +++ + D T K+W G Sbjct: 458 EPIHGNFLLTGAYDNTAKIWTHPG 481
>GBB_ARATH (P49177) Guanine nucleotide-binding protein beta subunit| (transducin) (AGB1) Length = 377 Score = 57.0 bits (136), Expect = 3e-08 Identities = 40/133 (30%), Positives = 69/133 (51%), Gaps = 2/133 (1%) Frame = +1 Query: 109 VMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 ++ GH V+ + +++SS D++ ++WD+T ++ +S +G F+ +GH Sbjct: 151 MLTGHRGYVSCCQYVPNEDAHLITSSGDQTCILWDVTTGLK-----TSVFGGEFQ--SGH 203 Query: 289 GHFVQDVVLS-SDGQFALSGSWDGELRLWDL-STGVTTRRFVGHEKDVLSVAFSIDNRQI 462 V V +S S+ + +SGS D RLWD + R F GHE DV +V F D + Sbjct: 204 TADVLSVSISGSNPNWFISGSCDSTARLWDTRAASRAVRTFHGHEGDVNTVKFFPDGYRF 263 Query: 463 VSASRDRTIKLWN 501 + S D T +L++ Sbjct: 264 GTGSDDGTCRLYD 276 Score = 47.4 bits (111), Expect = 3e-05 Identities = 42/157 (26%), Positives = 66/157 (42%), Gaps = 6/157 (3%) Frame = +1 Query: 79 GAQESLVYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEY 258 G + S+ GH V +++ N + +S S D + +WD +A Sbjct: 189 GLKTSVFGGEFQSGHTADVLSVSISGSNPNWFISGSCDSTARLWDTRAASRAV------- 241 Query: 259 GVPFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFV----GHEKDV 426 R GH V V DG +GS DG RL+D+ TG + + G V Sbjct: 242 ----RTFHGHEGDVNTVKFFPDGYRFGTGSDDGTCRLYDIRTGHQLQVYQPHGDGENGPV 297 Query: 427 LSVAFSIDNRQIVSA-SRDRTIKLWNT-LGECKYTIG 531 S+AFS+ R + + + + T +W+T LGE +G Sbjct: 298 TSIAFSVSGRLLFAGYASNNTCYVWDTLLGEVVLDLG 334 Score = 34.3 bits (77), Expect = 0.24 Identities = 21/85 (24%), Positives = 37/85 (43%) Frame = +1 Query: 118 GHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHF 297 G N VT+IA + + + + VWD + + G+ + H + Sbjct: 292 GENGPVTSIAFSVSGRLLFAGYASNNTCYVWDTL-----LGEVVLDLGL---QQDSHRNR 343 Query: 298 VQDVVLSSDGQFALSGSWDGELRLW 372 + + LS+DG +GSWD L++W Sbjct: 344 ISCLGLSADGSALCTGSWDSNLKIW 368 Score = 30.4 bits (67), Expect = 3.5 Identities = 15/40 (37%), Positives = 23/40 (57%) Frame = +1 Query: 388 VTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNTL 507 V R GH V S+ ++ + +IVSAS+D + +WN L Sbjct: 56 VCCRTLQGHTGKVYSLDWTPERNRIVSASQDGRLIVWNAL 95
>GBB_ORYSA (Q40687) Guanine nucleotide-binding protein beta subunit| Length = 380 Score = 57.0 bits (136), Expect = 3e-08 Identities = 40/133 (30%), Positives = 68/133 (51%), Gaps = 2/133 (1%) Frame = +1 Query: 109 VMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 ++ GH V++ D +++SS D++ ++WD+T T S +G F +GH Sbjct: 152 ILTGHKGYVSSCQYVPDQETRLITSSGDQTCVLWDVT-----TGQRISIFGGEFP--SGH 204 Query: 289 GHFVQDV-VLSSDGQFALSGSWDGELRLWDLS-TGVTTRRFVGHEKDVLSVAFSIDNRQI 462 V + + SS+ +SGS D +RLWD+ R + GHE D+ SV F D ++ Sbjct: 205 TADVLSLSINSSNSNMFVSGSCDATVRLWDIRIASRAVRTYHGHEGDINSVKFFPDGQRF 264 Query: 463 VSASRDRTIKLWN 501 + S D T +L++ Sbjct: 265 GTGSDDGTCRLFD 277 Score = 48.1 bits (113), Expect = 2e-05 Identities = 40/138 (28%), Positives = 60/138 (43%), Gaps = 8/138 (5%) Frame = +1 Query: 118 GHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHF 297 GH V +++ NS VS S D ++ +WD+ +A R GH Sbjct: 203 GHTADVLSLSINSSNSNMFVSGSCDATVRLWDIRIASRAV-----------RTYHGHEGD 251 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKD--------VLSVAFSIDN 453 + V DGQ +GS DG RL+D+ TG + + E D V S+AFSI Sbjct: 252 INSVKFFPDGQRFGTGSDDGTCRLFDVRTGHQLQVY-SREPDRNDNELPTVTSIAFSISG 310 Query: 454 RQIVSASRDRTIKLWNTL 507 R + + + +W+TL Sbjct: 311 RLLFAGYSNGDCYVWDTL 328 Score = 43.5 bits (101), Expect = 4e-04 Identities = 56/219 (25%), Positives = 88/219 (40%), Gaps = 53/219 (24%) Frame = +1 Query: 4 ISSLRRRLHRTPR--------KP*RSLRHTTMAGAQESLVYAGVMRGHNDVVTAIA-TPI 156 ++SLR RL + + + R+ T ++ LV ++GH+ V ++ TP Sbjct: 18 VNSLRERLRQRRQMLLDTDVERYSRTQGRTPVSFNPTDLVCCRTLQGHSGKVYSLDWTPE 77 Query: 157 DNSPFIVSSSRDKSLLVWD-LTNP-----------------------------------I 228 N +IVS+S+D L+VW+ LT+ Sbjct: 78 KN--WIVSASQDGRLIVWNALTSQKTHAIKLHCPWVMTCAFAPNGQSVACGGLDSACSIF 135 Query: 229 QATQDTSSEYGVPFRR-LTGHGHFVQDVVLSSDGQFAL-SGSWDGELRLWDLSTGVTTRR 402 + +P R LTGH +V D + L + S D LWD++TG Sbjct: 136 NLNSQADRDGNIPVSRILTGHKGYVSSCQYVPDQETRLITSSGDQTCVLWDVTTGQRISI 195 Query: 403 F-----VGHEKDVLSVAFSIDN-RQIVSASRDRTIKLWN 501 F GH DVLS++ + N VS S D T++LW+ Sbjct: 196 FGGEFPSGHTADVLSLSINSSNSNMFVSGSCDATVRLWD 234 Score = 30.8 bits (68), Expect = 2.7 Identities = 16/38 (42%), Positives = 19/38 (50%) Frame = +1 Query: 313 LSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDV 426 LSSDG +GSWD L++W F GH K V Sbjct: 352 LSSDGSALCTGSWDKNLKIW---------AFSGHRKIV 380 Score = 29.6 bits (65), Expect = 5.9 Identities = 15/40 (37%), Positives = 22/40 (55%) Frame = +1 Query: 388 VTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNTL 507 V R GH V S+ ++ + IVSAS+D + +WN L Sbjct: 57 VCCRTLQGHSGKVYSLDWTPEKNWIVSASQDGRLIVWNAL 96
>GBB4_HUMAN (Q9HAV0) Guanine nucleotide-binding protein beta subunit 4| (Transducin beta chain 4) Length = 339 Score = 57.0 bits (136), Expect = 3e-08 Identities = 34/110 (30%), Positives = 56/110 (50%) Frame = +1 Query: 172 IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSW 351 IV+SS D + +WD I+ Q T++ TGH V + LS D + +SG+ Sbjct: 156 IVTSSGDTTCALWD----IETAQQTTT--------FTGHSGDVMSLSLSPDMRTFVSGAC 203 Query: 352 DGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN 501 D +LWD+ G+ + F GH D+ +V+F + + S D T +L++ Sbjct: 204 DASSKLWDIRDGMCRQSFTGHVSDINAVSFFPNGYAFATGSDDATCRLFD 253 Score = 55.5 bits (132), Expect = 1e-07 Identities = 52/176 (29%), Positives = 72/176 (40%), Gaps = 35/176 (19%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWD--LTNPIQATQDTSS----------- 252 +RGH + A+ D S +VS+S+D L++WD TN + A SS Sbjct: 50 LRGHLAKIYAMHWGYD-SRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAPSG 108 Query: 253 --------------------EYGVPF-RRLTGHGHFVQDVVLSSDGQFALSGSWDGELRL 369 E V R L GH ++ D Q S S D L Sbjct: 109 NYVACGGLDNICSIYNLKTREGNVRVSRELPGHTGYLSCCRFLDDSQIVTS-SGDTTCAL 167 Query: 370 WDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNTL-GECKYTIGG 534 WD+ T T F GH DV+S++ S D R VS + D + KLW+ G C+ + G Sbjct: 168 WDIETAQQTTTFTGHSGDVMSLSLSPDMRTFVSGACDASSKLWDIRDGMCRQSFTG 223 Score = 36.2 bits (82), Expect = 0.063 Identities = 17/68 (25%), Positives = 29/68 (42%) Frame = +1 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASR 477 + V S G+ L+G D +WD G GH+ V + + D + + S Sbjct: 272 ITSVAFSKSGRLLLAGYDDFNCNVWDTLKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSW 331 Query: 478 DRTIKLWN 501 D +++WN Sbjct: 332 DSFLRIWN 339 Score = 33.5 bits (75), Expect = 0.41 Identities = 26/99 (26%), Positives = 46/99 (46%), Gaps = 2/99 (2%) Frame = +1 Query: 85 QESLVYAGVMRGHNDVVTAIATPI--DNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEY 258 QE L+Y+ H++++ I + + +++ D + VWD +A Sbjct: 258 QELLLYS-----HDNIICGITSVAFSKSGRLLLAGYDDFNCNVWDTLKGDRA-------- 304 Query: 259 GVPFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWD 375 GV L GH + V + ++ DG +GSWD LR+W+ Sbjct: 305 GV----LAGHDNRVSCLGVTDDGMAVATGSWDSFLRIWN 339
>PRP46_CRYNE (Q5KDR4) Pre-mRNA-splicing factor PRP46 (Pre-mRNA-processing| protein 46) Length = 473 Score = 57.0 bits (136), Expect = 3e-08 Identities = 39/142 (27%), Positives = 60/142 (42%), Gaps = 3/142 (2%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 + GH + +A D P++ S + DK + WDL T Y HG Sbjct: 220 LTGHISTIRGLAVS-DRHPYLFSCAEDKMVKCWDLE-----TNKVIRHY---------HG 264 Query: 292 HF--VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIV 465 HF V + + ++G D +R+WD+ T GH V V + QI+ Sbjct: 265 HFSGVYSLSVHPTLDVLVTGGRDASVRVWDMRTRANIFTLTGHTSTVGDVKTQDSDPQII 324 Query: 466 SASRDRTIKLWN-TLGECKYTI 528 S S D T++LW+ G+C T+ Sbjct: 325 SGSMDSTVRLWDLAAGKCMNTL 346 Score = 48.9 bits (115), Expect = 9e-06 Identities = 34/110 (30%), Positives = 44/110 (40%), Gaps = 1/110 (0%) Frame = +1 Query: 172 IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSW 351 +V+ RD S+ VWD+ LTGH V DV +SGS Sbjct: 281 LVTGGRDASVRVWDMRTRANIFT------------LTGHTSTVGDVKTQDSDPQIISGSM 328 Query: 352 DGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASR-DRTIKLW 498 D +RLWDL+ G H+K V ++A SAS IK W Sbjct: 329 DSTVRLWDLAAGKCMNTLTHHKKSVRALAIHPTEYSFASASSGGNNIKKW 378 Score = 47.8 bits (112), Expect = 2e-05 Identities = 33/131 (25%), Positives = 60/131 (45%), Gaps = 1/131 (0%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 + GH V + T D+ P I+S S D ++ +WDL G LT H Sbjct: 304 LTGHTSTVGDVKTQ-DSDPQIISGSMDSTVRLWDLAA------------GKCMNTLTHHK 350 Query: 292 HFVQDVVLS-SDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVS 468 V+ + + ++ FA + S ++ W G+ FVGHE + +++ + +N + S Sbjct: 351 KSVRALAIHPTEYSFASASSGGNNIKKWKCPEGIFVNNFVGHEAIINTLSINSEN-VLFS 409 Query: 469 ASRDRTIKLWN 501 + + T+ LW+ Sbjct: 410 GADNGTLTLWD 420 Score = 45.1 bits (105), Expect = 1e-04 Identities = 20/77 (25%), Positives = 41/77 (53%) Frame = +1 Query: 271 RRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSID 450 R ++GH +V+ V + Q+ +G+ D +++WDL++G GH + +A S Sbjct: 176 RVISGHMGWVRAVAMDPGNQWFATGAGDRVIKIWDLASGELKLSLTGHISTIRGLAVSDR 235 Query: 451 NRQIVSASRDRTIKLWN 501 + + S + D+ +K W+ Sbjct: 236 HPYLFSCAEDKMVKCWD 252 Score = 29.6 bits (65), Expect = 5.9 Identities = 17/50 (34%), Positives = 26/50 (52%), Gaps = 1/50 (2%) Frame = +1 Query: 394 TRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN-TLGECKYTIGGDL 540 TR GH V +VA N+ + + DR IK+W+ GE K ++ G + Sbjct: 175 TRVISGHMGWVRAVAMDPGNQWFATGAGDRVIKIWDLASGELKLSLTGHI 224
>PRP4_PONPY (Q5NVD0) U4/U6 small nuclear ribonucleoprotein Prp4 (U4/U6 snRNP 60| kDa protein) (WD splicing factor Prp4) Length = 521 Score = 57.0 bits (136), Expect = 3e-08 Identities = 37/121 (30%), Positives = 56/121 (46%), Gaps = 1/121 (0%) Frame = +1 Query: 169 FIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGS 348 F+ ++ D+S +WDL +A ++ + GH V D+ DG A +G Sbjct: 336 FLGTTCYDRSWRLWDL----EAQEEILHQ--------EGHSMGVYDIAFHQDGSLAGTGG 383 Query: 349 WDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN-TLGECKYT 525 D R+WDL TG GH K++ + FS + I + S D T K+W+ C YT Sbjct: 384 LDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYT 443 Query: 526 I 528 I Sbjct: 444 I 444 Score = 48.9 bits (115), Expect = 9e-06 Identities = 33/114 (28%), Positives = 48/114 (42%), Gaps = 1/114 (0%) Frame = +1 Query: 160 NSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSS-DGQFA 336 N I + S D + VWDL + Y +P H + V V G F Sbjct: 417 NGYHIATGSGDNTCKVWDL-------RQRRCVYTIP-----AHQNLVTGVKFEPIHGNFL 464 Query: 337 LSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLW 498 L+G++D ++W + GHE V+ + S D + I + S DRT KLW Sbjct: 465 LTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLW 518 Score = 39.3 bits (90), Expect = 0.007 Identities = 38/151 (25%), Positives = 56/151 (37%), Gaps = 8/151 (5%) Frame = +1 Query: 112 MRGHNDVVTAIA------TPIDNSPF-IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPF 270 +RGHN V AI +D + S + D S+ +W L + P Sbjct: 268 LRGHNTNVGAIVFHPKSTVSLDQKDVNLASCAADGSVKLWSLDSD------------EPV 315 Query: 271 RRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSID 450 + GH V V+ G+F + +D RLWDL GH V +AF D Sbjct: 316 ADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQD 375 Query: 451 NRQIVSASRDRTIKLWN-TLGECKYTIGGDL 540 + D ++W+ G C + G L Sbjct: 376 GSLAGTGGLDAFGRVWDLRTGRCIMFLEGHL 406 Score = 35.4 bits (80), Expect = 0.11 Identities = 37/144 (25%), Positives = 54/144 (37%), Gaps = 1/144 (0%) Frame = +1 Query: 82 AQESLVYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYG 261 AQE +++ GH+ V IA D S + D VWDL G Sbjct: 353 AQEEILH---QEGHSMGVYDIAFHQDGS-LAGTGGLDAFGRVWDLRT------------G 396 Query: 262 VPFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAF 441 L GH + + S +G +GS D ++WDL H+ V V F Sbjct: 397 RCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKF 456 Query: 442 S-IDNRQIVSASRDRTIKLWNTLG 510 I +++ + D T K+W G Sbjct: 457 EPIHGNFLLTGAYDNTAKIWTHPG 480 Score = 29.3 bits (64), Expect = 7.8 Identities = 16/70 (22%), Positives = 31/70 (44%), Gaps = 8/70 (11%) Frame = +1 Query: 316 SSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAF------SIDNRQI--VSA 471 S + + + W G +LW + GH +V ++ F S+D + + S Sbjct: 239 SPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDQKDVNLASC 298 Query: 472 SRDRTIKLWN 501 + D ++KLW+ Sbjct: 299 AADGSVKLWS 308
>PRP4_MOUSE (Q9DAW6) U4/U6 small nuclear ribonucleoprotein Prp4 (U4/U6 snRNP 60| kDa protein) (WD splicing factor Prp4) Length = 521 Score = 57.0 bits (136), Expect = 3e-08 Identities = 37/121 (30%), Positives = 56/121 (46%), Gaps = 1/121 (0%) Frame = +1 Query: 169 FIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGS 348 F+ ++ D+S +WDL +A ++ + GH V D+ DG A +G Sbjct: 336 FLGTTCYDRSWRLWDL----EAQEEILHQ--------EGHSMGVYDIAFHQDGSLAGTGG 383 Query: 349 WDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN-TLGECKYT 525 D R+WDL TG GH K++ + FS + I + S D T K+W+ C YT Sbjct: 384 LDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYT 443 Query: 526 I 528 I Sbjct: 444 I 444 Score = 48.9 bits (115), Expect = 9e-06 Identities = 33/114 (28%), Positives = 48/114 (42%), Gaps = 1/114 (0%) Frame = +1 Query: 160 NSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSS-DGQFA 336 N I + S D + VWDL + Y +P H + V V G F Sbjct: 417 NGYHIATGSGDNTCKVWDL-------RQRRCVYTIP-----AHQNLVTGVKFEPIHGDFL 464 Query: 337 LSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLW 498 L+G++D ++W + GHE V+ + S D + I + S DRT KLW Sbjct: 465 LTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLW 518 Score = 39.3 bits (90), Expect = 0.007 Identities = 38/151 (25%), Positives = 56/151 (37%), Gaps = 8/151 (5%) Frame = +1 Query: 112 MRGHNDVVTAIA------TPIDNSPF-IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPF 270 +RGHN V AI +D + S + D S+ +W L + P Sbjct: 268 LRGHNTNVGAIVFHPKSTVSLDQKDVNLASCAADGSVKLWSLDSD------------EPV 315 Query: 271 RRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSID 450 + GH V V+ G+F + +D RLWDL GH V +AF D Sbjct: 316 ADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQD 375 Query: 451 NRQIVSASRDRTIKLWN-TLGECKYTIGGDL 540 + D ++W+ G C + G L Sbjct: 376 GSLAGTGGLDAFGRVWDLRTGRCIMFLEGHL 406 Score = 34.7 bits (78), Expect = 0.18 Identities = 37/144 (25%), Positives = 54/144 (37%), Gaps = 1/144 (0%) Frame = +1 Query: 82 AQESLVYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYG 261 AQE +++ GH+ V IA D S + D VWDL G Sbjct: 353 AQEEILH---QEGHSMGVYDIAFHQDGS-LAGTGGLDAFGRVWDLRT------------G 396 Query: 262 VPFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAF 441 L GH + + S +G +GS D ++WDL H+ V V F Sbjct: 397 RCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKF 456 Query: 442 S-IDNRQIVSASRDRTIKLWNTLG 510 I +++ + D T K+W G Sbjct: 457 EPIHGDFLLTGAYDNTAKIWTHPG 480 Score = 29.6 bits (65), Expect = 5.9 Identities = 16/70 (22%), Positives = 31/70 (44%), Gaps = 8/70 (11%) Frame = +1 Query: 316 SSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAF------SIDNRQI--VSA 471 S + + + W G +LW + GH +V ++ F S+D + + S Sbjct: 239 SPNSKMLATACWSGLCKLWSVPDCSLLHTLRGHNTNVGAIVFHPKSTVSLDQKDVNLASC 298 Query: 472 SRDRTIKLWN 501 + D ++KLW+ Sbjct: 299 AADGSVKLWS 308
>CDC4_CANAL (P53699) Cell division control protein 4| Length = 684 Score = 56.6 bits (135), Expect = 5e-08 Identities = 40/129 (31%), Positives = 58/129 (44%), Gaps = 6/129 (4%) Frame = +1 Query: 166 PFIVSSSRDKSLLVWDLTNPIQATQD----TSSEYGVPFRRLTGHGHFVQDVVLSSDGQF 333 P +++ SRD ++ VW L + +QD E+ P+ GH +S G Sbjct: 434 PLLITGSRDHNIHVWKLP-VVDDSQDYIETFEGEFDNPYLIAVLSGHTQSVRSISGYGNI 492 Query: 334 ALSGSWDGELRLWD-LSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN-TL 507 +SGS+D +R+WD L G T GH V S A ++ S S D I +WN Sbjct: 493 IISGSYDSTVRVWDLLDDGHCTHVLQGHLDRVYSTAIDFHSKTCFSGSMDSNINVWNFET 552 Query: 508 GECKYTIGG 534 GE K + G Sbjct: 553 GELKKVLVG 561 Score = 51.2 bits (121), Expect = 2e-06 Identities = 40/156 (25%), Positives = 65/156 (41%), Gaps = 1/156 (0%) Frame = +1 Query: 70 TMAGAQESLVYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTS 249 T G ++ V+ GH V +I+ I+S S D ++ VWDL + T Sbjct: 462 TFEGEFDNPYLIAVLSGHTQSVRSIS---GYGNIIISGSYDSTVRVWDLLDDGHCTHV-- 516 Query: 250 SEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVL 429 L GH V + + SGS D + +W+ TG + VGH L Sbjct: 517 ---------LQGHLDRVYSTAIDFHSKTCFSGSMDSNINVWNFETGELKKVLVGHAS--L 565 Query: 430 SVAFSIDNRQIVSASRDRTIKLWNT-LGECKYTIGG 534 + + +VSA+ D T+++W+ GE + + G Sbjct: 566 VGLLDLVDDVLVSAAADATLRIWDAKTGELRSKLKG 601 Score = 39.7 bits (91), Expect = 0.006 Identities = 24/87 (27%), Positives = 45/87 (51%), Gaps = 1/87 (1%) Frame = +1 Query: 277 LTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNR 456 ++GHG+ V L D + ++G D + ++ TG + GHE V ++ ++ Sbjct: 320 VSGHGNKVV-TCLQHDDEKVVTGVDDKCISIYSTQTGQLMKVLEGHEGGVWALKYT--GN 376 Query: 457 QIVSASRDRTIKLWN-TLGECKYTIGG 534 +V+ S DRT+++WN G+C + G Sbjct: 377 TLVTGSTDRTVRVWNMKTGQCTHIFRG 403 Score = 34.3 bits (77), Expect = 0.24 Identities = 27/100 (27%), Positives = 43/100 (43%), Gaps = 16/100 (16%) Frame = +1 Query: 247 SSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEK-- 420 S++ G + L GH V L G ++GS D +R+W++ TG T F GH Sbjct: 351 STQTGQLMKVLEGHEGGVW--ALKYTGNTLVTGSTDRTVRVWNMKTGQCTHIFRGHTSTI 408 Query: 421 ---DVLSVAFSIDNRQ-----------IVSASRDRTIKLW 498 D++ A N+ +++ SRD I +W Sbjct: 409 RCLDIIHPAVIGKNQDGEDIVFPEYPLLITGSRDHNIHVW 448
>GBB_DICDI (P36408) Guanine nucleotide-binding protein beta subunit| Length = 347 Score = 56.6 bits (135), Expect = 5e-08 Identities = 32/114 (28%), Positives = 56/114 (49%) Frame = +1 Query: 160 NSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFAL 339 N IV+SS D + ++WD+ N + T+ + H V V +S D + + Sbjct: 160 NDRQIVTSSGDMTCILWDVENGTKITE------------FSDHNGDVMSVSVSPDKNYFI 207 Query: 340 SGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN 501 SG+ D +LWDL +G + F GHE D+ +V + + + S D + +L++ Sbjct: 208 SGACDATAKLWDLRSGKCVQTFTGHEADINAVQYFPNGLSFGTGSDDASCRLFD 261 Score = 42.0 bits (97), Expect = 0.001 Identities = 41/149 (27%), Positives = 64/149 (42%), Gaps = 4/149 (2%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWD-LTNPIQATQDTSSEYGVPFRRLTGH 288 ++GH + A+ DN +VS+S+D LLVWD LT T+ + +P R Sbjct: 58 LKGHLAKIYAMHWAEDNV-HLVSASQDGKLLVWDGLT--------TNKVHAIPLR----- 103 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDLSTG---VTTRRFVGHEKDVLSVAFSIDNRQ 459 +V S F G D +++L + + R + LS +++RQ Sbjct: 104 SSWVMTCAYSPTANFVACGGLDNICSIYNLRSREQPIRVCRELNSHTGYLSCCRFLNDRQ 163 Query: 460 IVSASRDRTIKLWNTLGECKYTIGGDLGG 546 IV++S D T LW+ K T D G Sbjct: 164 IVTSSGDMTCILWDVENGTKITEFSDHNG 192 Score = 35.0 bits (79), Expect = 0.14 Identities = 14/32 (43%), Positives = 21/32 (65%) Frame = +1 Query: 277 LTGHGHFVQDVVLSSDGQFALSGSWDGELRLW 372 LTGHG+ V + + +DG +GSWD L++W Sbjct: 315 LTGHGNRVSCLGVPTDGMALCTGSWDSLLKIW 346 Score = 32.7 bits (73), Expect = 0.70 Identities = 17/67 (25%), Positives = 26/67 (38%) Frame = +1 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASR 477 + V S G+F +G D +WD G GH V + D + + S Sbjct: 280 ITSVGFSFSGRFLFAGYDDFTCNVWDTLKGERVLSLTGHGNRVSCLGVPTDGMALCTGSW 339 Query: 478 DRTIKLW 498 D +K+W Sbjct: 340 DSLLKIW 346
>PRP4_ARATH (O22212) U4/U6 small nuclear ribonucleoprotein PRP4-like protein| Length = 554 Score = 56.6 bits (135), Expect = 5e-08 Identities = 36/128 (28%), Positives = 54/128 (42%) Frame = +1 Query: 118 GHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHF 297 GH D + +A + ++ ++S DK+ +WD+ G GH Sbjct: 337 GHLDRLARVAFH-PSGKYLGTTSYDKTWRLWDINT------------GAELLLQEGHSRS 383 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASR 477 V + DG A S D R+WDL TG + F GH K V SV FS + + S Sbjct: 384 VYGIAFQQDGALAASCGLDSLARVWDLRTGRSILVFQGHIKPVFSVNFSPNGYHLASGGE 443 Query: 478 DRTIKLWN 501 D ++W+ Sbjct: 444 DNQCRIWD 451 Score = 51.2 bits (121), Expect = 2e-06 Identities = 37/135 (27%), Positives = 57/135 (42%), Gaps = 1/135 (0%) Frame = +1 Query: 109 VMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 V +GH V ++ N + S D +WDL + S Y +P H Sbjct: 418 VFQGHIKPVFSVNFS-PNGYHLASGGEDNQCRIWDL-------RMRKSLYIIP-----AH 464 Query: 289 GHFVQDVVLS-SDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIV 465 + V V +G F + S+D ++ +W + GHE V S+ + D+ I Sbjct: 465 ANLVSQVKYEPQEGYFLATASYDMKVNIWSGRDFSLVKSLAGHESKVASLDITADSSCIA 524 Query: 466 SASRDRTIKLWNTLG 510 + S DRTIKLW + G Sbjct: 525 TVSHDRTIKLWTSSG 539 Score = 46.6 bits (109), Expect = 5e-05 Identities = 30/132 (22%), Positives = 57/132 (43%), Gaps = 1/132 (0%) Frame = +1 Query: 109 VMRGHNDVVTAIA-TPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTG 285 V++ H + T + +P+D+ + ++S D++ +W + T + G Sbjct: 293 VLKDHKERATDVVFSPVDDC--LATASADRTAKLWKTDGTLLQTFE-------------G 337 Query: 286 HGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIV 465 H + V G++ + S+D RLWD++TG GH + V +AF D Sbjct: 338 HLDRLARVAFHPSGKYLGTTSYDKTWRLWDINTGAELLLQEGHSRSVYGIAFQQDGALAA 397 Query: 466 SASRDRTIKLWN 501 S D ++W+ Sbjct: 398 SCGLDSLARVWD 409 Score = 39.7 bits (91), Expect = 0.006 Identities = 25/76 (32%), Positives = 36/76 (47%), Gaps = 1/76 (1%) Frame = +1 Query: 316 SSDGQFALSGSWDGELRLWDLSTGVTTRRFV-GHEKDVLSVAFSIDNRQIVSASRDRTIK 492 S DG+ + S G +LW++ T + H++ V FS + + +AS DRT K Sbjct: 264 SRDGKILATCSLSGVTKLWEMPQVTNTIAVLKDHKERATDVVFSPVDDCLATASADRTAK 323 Query: 493 LWNTLGECKYTIGGDL 540 LW T G T G L Sbjct: 324 LWKTDGTLLQTFEGHL 339
>GBB1_DROME (P26308) Guanine nucleotide-binding protein beta subunit 1| Length = 340 Score = 56.6 bits (135), Expect = 5e-08 Identities = 37/128 (28%), Positives = 59/128 (46%) Frame = +1 Query: 118 GHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHF 297 GH ++ DN IV+SS D S +WD+ +Q T GH Sbjct: 141 GHGGYLSCCRFLDDNQ--IVTSSGDMSCGLWDIETGLQVTS------------FLGHTGD 186 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASR 477 V + L+ + +SG+ D +LWD+ GV + F GHE D+ +V F + + + S Sbjct: 187 VMALSLAPQCKTFVSGACDASAKLWDIREGVCKQTFPGHESDINAVTFFPNGQAFATGSD 246 Query: 478 DRTIKLWN 501 D T +L++ Sbjct: 247 DATCRLFD 254 Score = 37.7 bits (86), Expect = 0.022 Identities = 34/133 (25%), Positives = 54/133 (40%), Gaps = 3/133 (2%) Frame = +1 Query: 118 GHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHF 297 GH V A++ F VS + D S +WD+ GV + GH Sbjct: 182 GHTGDVMALSLAPQCKTF-VSGACDASAKLWDIRE------------GVCKQTFPGHESD 228 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEK---DVLSVAFSIDNRQIVS 468 + V +GQ +GS D RL+D+ + H+ + SVAFS R +++ Sbjct: 229 INAVTFFPNGQAFATGSDDATCRLFDIRADQELAMY-SHDNIICGITSVAFSKSGRLLLA 287 Query: 469 ASRDRTIKLWNTL 507 D +W+T+ Sbjct: 288 GYDDFNCNVWDTM 300 Score = 32.7 bits (73), Expect = 0.70 Identities = 15/68 (22%), Positives = 29/68 (42%) Frame = +1 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASR 477 + V S G+ L+G D +WD + GH+ V + + + + + S Sbjct: 273 ITSVAFSKSGRLLLAGYDDFNCNVWDTMKAERSGILAGHDNRVSCLGVTENGMAVATGSW 332 Query: 478 DRTIKLWN 501 D +++WN Sbjct: 333 DSFLRVWN 340 Score = 30.4 bits (67), Expect = 3.5 Identities = 12/33 (36%), Positives = 20/33 (60%) Frame = +1 Query: 277 LTGHGHFVQDVVLSSDGQFALSGSWDGELRLWD 375 L GH + V + ++ +G +GSWD LR+W+ Sbjct: 308 LAGHDNRVSCLGVTENGMAVATGSWDSFLRVWN 340
>APAF_MOUSE (O88879) Apoptotic protease-activating factor 1 (Apaf-1)| Length = 1249 Score = 56.6 bits (135), Expect = 5e-08 Identities = 41/128 (32%), Positives = 60/128 (46%) Frame = +1 Query: 118 GHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHF 297 GH V I D ++SSS D + VW+ + +Y L H Sbjct: 1001 GHKKAVRHIQFTADGKT-LISSSEDSVIQVWNWQ---------TGDYVF----LQAHQET 1046 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASR 477 V+D L D + LS S+DG +++W++ TG R F H+ VLS A S D + S S Sbjct: 1047 VKDFRLLQDSRL-LSWSFDGTVKVWNVITGRIERDFTCHQGTVLSCAISSDATKFSSTSA 1105 Query: 478 DRTIKLWN 501 D+T K+W+ Sbjct: 1106 DKTAKIWS 1113 Score = 54.3 bits (129), Expect = 2e-07 Identities = 41/131 (31%), Positives = 58/131 (44%), Gaps = 1/131 (0%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWD-LTNPIQATQDTSSEYGVPFRRLTGH 288 ++ H D V A D+S +I + S DK + +WD T + T D SE Sbjct: 653 IKAHEDEVLCCAFSSDDS-YIATCSADKKVKIWDSATGKLVHTYDEHSEQ-------VNC 704 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVS 468 HF SS+ +GS D L+LWDL+ GH V FS D+ + S Sbjct: 705 CHFTN----SSNHLLLATGSNDFFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDELLAS 760 Query: 469 ASRDRTIKLWN 501 S D T++LW+ Sbjct: 761 CSADGTLRLWD 771 Score = 43.9 bits (102), Expect = 3e-04 Identities = 24/73 (32%), Positives = 35/73 (47%) Frame = +1 Query: 286 HGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIV 465 H V S DGQ S D L+++ TG HE +VL AFS D+ I Sbjct: 614 HTDAVYHACFSQDGQRIASCGADKTLQVFKAETGEKLLDIKAHEDEVLCCAFSSDDSYIA 673 Query: 466 SASRDRTIKLWNT 504 + S D+ +K+W++ Sbjct: 674 TCSADKKVKIWDS 686 Score = 42.4 bits (98), Expect = 9e-04 Identities = 38/136 (27%), Positives = 55/136 (40%), Gaps = 9/136 (6%) Frame = +1 Query: 121 HNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFV 300 H V + A D + F S+S DK+ +W S + P L GH V Sbjct: 1084 HQGTVLSCAISSDATKFS-STSADKTAKIW------------SFDLLSPLHELKGHNGCV 1130 Query: 301 QDVVLSSDGQFALSGSWDGELRLWDLSTG---------VTTRRFVGHEKDVLSVAFSIDN 453 + S DG +G +GE+R+W++S G H V V FS D+ Sbjct: 1131 RCSAFSLDGILLATGDDNGEIRIWNVSDGQLLHSCAPISVEEGTATHGGWVTDVCFSPDS 1190 Query: 454 RQIVSASRDRTIKLWN 501 + +VSA +K WN Sbjct: 1191 KTLVSAG--GYLKWWN 1204 Score = 41.6 bits (96), Expect = 0.002 Identities = 19/63 (30%), Positives = 34/63 (53%) Frame = +1 Query: 313 LSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIK 492 LS ++ G DG +++ +L VGH+K V + F+ D + ++S+S D I+ Sbjct: 969 LSPHLEYVAFGDEDGAIKIIELPNNRVFSSGVGHKKAVRHIQFTADGKTLISSSEDSVIQ 1028 Query: 493 LWN 501 +WN Sbjct: 1029 VWN 1031 Score = 41.2 bits (95), Expect = 0.002 Identities = 38/145 (26%), Positives = 60/145 (41%), Gaps = 3/145 (2%) Frame = +1 Query: 109 VMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 V+R H D V D I S DK+L V+ +E G + H Sbjct: 610 VVRPHTDAVYHACFSQDGQR-IASCGADKTLQVF------------KAETGEKLLDIKAH 656 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVS 468 V SSD + + S D ++++WD +TG + H + V F+ + ++ Sbjct: 657 EDEVLCCAFSSDDSYIATCSADKKVKIWDSATGKLVHTYDEHSEQVNCCHFTNSSNHLLL 716 Query: 469 A--SRDRTIKLWN-TLGECKYTIGG 534 A S D +KLW+ EC+ T+ G Sbjct: 717 ATGSNDFFLKLWDLNQKECRNTMFG 741 Score = 38.9 bits (89), Expect = 0.010 Identities = 24/80 (30%), Positives = 36/80 (45%) Frame = +1 Query: 280 TGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQ 459 TGH +Q S A+ + LW++ + + GH V V FS D Sbjct: 837 TGHHSTIQYCDFSPYDHLAVIALSQYCVELWNIDSRLKVADCRGHLSWVHGVMFSPDGSS 896 Query: 460 IVSASRDRTIKLWNTLGECK 519 ++AS D+TI++W T CK Sbjct: 897 FLTASDDQTIRVWETKKVCK 916 Score = 38.1 bits (87), Expect = 0.017 Identities = 22/75 (29%), Positives = 40/75 (53%) Frame = +1 Query: 283 GHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQI 462 GH V+ + ++DG+ +S S D +++W+ TG H++ V D+R + Sbjct: 1001 GHKKAVRHIQFTADGKTLISSSEDSVIQVWNWQTGDYVF-LQAHQETVKDFRLLQDSR-L 1058 Query: 463 VSASRDRTIKLWNTL 507 +S S D T+K+WN + Sbjct: 1059 LSWSFDGTVKVWNVI 1073 Score = 36.2 bits (82), Expect = 0.063 Identities = 28/121 (23%), Positives = 57/121 (47%), Gaps = 2/121 (1%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNP--IQATQDTSSEYGVPFRRLTG 285 ++GHN V A +D + + + + +W++++ + + S E G Sbjct: 1123 LKGHNGCVRCSAFSLDGI-LLATGDDNGEIRIWNVSDGQLLHSCAPISVEEGT-----AT 1176 Query: 286 HGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIV 465 HG +V DV S D + +S G L+ W+++TG +++ F + ++ + S D R V Sbjct: 1177 HGGWVTDVCFSPDSKTLVSAG--GYLKWWNVATGDSSQTFYTNGTNLKKIHVSPDFRTYV 1234 Query: 466 S 468 + Sbjct: 1235 T 1235
>TBL1Y_HUMAN (Q9BQ87) F-box-like/WD-repeat protein TBL1Y (Transducin beta-like| 1Y protein) (Transducin-beta-like 1, Y-linked) Length = 522 Score = 56.2 bits (134), Expect = 6e-08 Identities = 40/139 (28%), Positives = 60/139 (43%), Gaps = 9/139 (6%) Frame = +1 Query: 115 RGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGH 294 +GH + V AI + + S S D +L +W + QD L H Sbjct: 356 QGHTNEVNAIKWD-PSGMLLASCSDDMTLKIWSMK------QDAC------VHDLQAHSK 402 Query: 295 FVQDVVLSSDGQ---------FALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSI 447 + + S G S S+D +RLWD+ GV T + H++ V SVAFS Sbjct: 403 EIYTIKWSPTGPATSNPNSSIMLASASFDSTVRLWDVEQGVCTHTLMKHQEPVYSVAFSP 462 Query: 448 DNRQIVSASRDRTIKLWNT 504 D + + S S D+ + +WNT Sbjct: 463 DGKYLASGSFDKYVHIWNT 481 Score = 38.9 bits (89), Expect = 0.010 Identities = 23/85 (27%), Positives = 39/85 (45%) Frame = +1 Query: 157 DNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFA 336 ++S + S+S D ++ +WD+ E GV L H V V S DG++ Sbjct: 420 NSSIMLASASFDSTVRLWDV------------EQGVCTHTLMKHQEPVYSVAFSPDGKYL 467 Query: 337 LSGSWDGELRLWDLSTGVTTRRFVG 411 SGS+D + +W+ +G + G Sbjct: 468 ASGSFDKYVHIWNTQSGSLVHSYQG 492 Score = 37.7 bits (86), Expect = 0.022 Identities = 23/98 (23%), Positives = 41/98 (41%), Gaps = 10/98 (10%) Frame = +1 Query: 265 PFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFS 444 P + GH + V + G S S D L++W + H K++ ++ +S Sbjct: 351 PVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDACVHDLQAHSKEIYTIKWS 410 Query: 445 ---------IDNRQIVSASRDRTIKLWNT-LGECKYTI 528 + + SAS D T++LW+ G C +T+ Sbjct: 411 PTGPATSNPNSSIMLASASFDSTVRLWDVEQGVCTHTL 448 Score = 32.7 bits (73), Expect = 0.70 Identities = 28/103 (27%), Positives = 41/103 (39%), Gaps = 14/103 (13%) Frame = +1 Query: 277 LTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDL-------STGVTTRRFV---GHE--- 417 L GH V + SGS D R+W+L ST + R + GH+ Sbjct: 175 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPS 234 Query: 418 -KDVLSVAFSIDNRQIVSASRDRTIKLWNTLGECKYTIGGDLG 543 KDV S+ ++ D + S D ++W G T+G G Sbjct: 235 NKDVTSLDWNSDGTLLAMGSYDGFARIWTENGNLASTLGQHKG 277
>TB1RB_XENLA (Q6GPC6) F-box-like/WD-repeat-containing protein TBL1XR1-B| (Transducin beta-like 1X-related homolog 1-B) (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1-B) (TBL1-related protein 1-B) Length = 522 Score = 56.2 bits (134), Expect = 6e-08 Identities = 41/133 (30%), Positives = 61/133 (45%), Gaps = 3/133 (2%) Frame = +1 Query: 115 RGHNDVVTAIA-TPIDNSPFIVSSSRDKSLLVWDLTNP--IQATQDTSSEYGVPFRRLTG 285 +GH + V AI P N + S S D +L +W + + + Q + E TG Sbjct: 354 QGHTNEVNAIKWDPTGN--LLASCSDDMTLKIWSMKHDTCVHDLQAHNKEIYTIKWSPTG 411 Query: 286 HGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIV 465 G + L S S+D +RLWD+ G+ H++ V SVAFS D R + Sbjct: 412 PGTNNPNANL-----MLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLA 466 Query: 466 SASRDRTIKLWNT 504 S S D+ + +WNT Sbjct: 467 SGSFDKCVHIWNT 479 Score = 41.2 bits (95), Expect = 0.002 Identities = 28/108 (25%), Positives = 47/108 (43%), Gaps = 8/108 (7%) Frame = +1 Query: 112 MRGHNDVVTAI----ATPIDNSP----FIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVP 267 ++ HN + I P N+P + S+S D ++ +WD+ + G+ Sbjct: 395 LQAHNKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVRLWDV------------DRGIC 442 Query: 268 FRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVG 411 LT H V V S DG++ SGS+D + +W+ TG + G Sbjct: 443 IHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSYRG 490 Score = 39.7 bits (91), Expect = 0.006 Identities = 38/148 (25%), Positives = 62/148 (41%), Gaps = 9/148 (6%) Frame = +1 Query: 103 AGVMRGHNDVVTAIA-TPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRL 279 A V+RGH V A P+ S + S S D + +W+L+ TS + R Sbjct: 170 AVVLRGHESEVFICAWNPV--SDLLASGSGDSTARIWNLSE-----NSTSGSTQLVLRHC 222 Query: 280 TGHG-------HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVA 438 G V + +S+G +GS+DG R+W G H+ + ++ Sbjct: 223 IREGGQDVPSNKDVTSLDWNSEGTLLATGSYDGFARIW-TKDGNLASTLGQHKGPIFALK 281 Query: 439 FSIDNRQIVSASRDRTIKLWNT-LGECK 519 ++ I+SA D+T +W+ GE K Sbjct: 282 WNKKGNFILSAGVDKTTIIWDAHTGEAK 309 Score = 38.1 bits (87), Expect = 0.017 Identities = 24/98 (24%), Positives = 41/98 (41%), Gaps = 10/98 (10%) Frame = +1 Query: 265 PFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFS 444 P + GH + V + G S S D L++W + H K++ ++ +S Sbjct: 349 PIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSMKHDTCVHDLQAHNKEIYTIKWS 408 Query: 445 ID---------NRQIVSASRDRTIKLWNT-LGECKYTI 528 N + SAS D T++LW+ G C +T+ Sbjct: 409 PTGPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTL 446 Score = 31.2 bits (69), Expect = 2.0 Identities = 26/103 (25%), Positives = 41/103 (39%), Gaps = 14/103 (13%) Frame = +1 Query: 277 LTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLS---TGVTTRRFVGH----------- 414 L GH V + SGS D R+W+LS T +T+ + H Sbjct: 173 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVPS 232 Query: 415 EKDVLSVAFSIDNRQIVSASRDRTIKLWNTLGECKYTIGGDLG 543 KDV S+ ++ + + + S D ++W G T+G G Sbjct: 233 NKDVTSLDWNSEGTLLATGSYDGFARIWTKDGNLASTLGQHKG 275 Score = 29.3 bits (64), Expect = 7.8 Identities = 18/55 (32%), Positives = 22/55 (40%) Frame = +1 Query: 325 GQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTI 489 G F LS D +WD TG ++F H L V + N S S D I Sbjct: 286 GNFILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQ-SNNTFASCSTDMCI 339
>TB1RA_XENLA (Q7SZM9) F-box-like/WD-repeat-containing protein TBL1XR1-A| (Transducin beta-like 1X-related protein 1-A) (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1-A) (TBL1-related protein 1-A) (xTBLR1) Length = 519 Score = 56.2 bits (134), Expect = 6e-08 Identities = 41/133 (30%), Positives = 61/133 (45%), Gaps = 3/133 (2%) Frame = +1 Query: 115 RGHNDVVTAIA-TPIDNSPFIVSSSRDKSLLVWDLTNP--IQATQDTSSEYGVPFRRLTG 285 +GH + V AI P N + S S D +L +W + + + Q + E TG Sbjct: 351 QGHTNEVNAIKWDPTGN--LLASCSDDMTLKIWSMKHDTCVHDLQAHNKEIYTIKWSPTG 408 Query: 286 HGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIV 465 G + L S S+D +RLWD+ G+ H++ V SVAFS D R + Sbjct: 409 PGTNNPNANL-----MLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLA 463 Query: 466 SASRDRTIKLWNT 504 S S D+ + +WNT Sbjct: 464 SGSFDKCVHIWNT 476 Score = 41.2 bits (95), Expect = 0.002 Identities = 28/108 (25%), Positives = 47/108 (43%), Gaps = 8/108 (7%) Frame = +1 Query: 112 MRGHNDVVTAI----ATPIDNSP----FIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVP 267 ++ HN + I P N+P + S+S D ++ +WD+ + G+ Sbjct: 392 LQAHNKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVRLWDV------------DRGIC 439 Query: 268 FRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVG 411 LT H V V S DG++ SGS+D + +W+ TG + G Sbjct: 440 IHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSYRG 487 Score = 39.7 bits (91), Expect = 0.006 Identities = 38/148 (25%), Positives = 62/148 (41%), Gaps = 9/148 (6%) Frame = +1 Query: 103 AGVMRGHNDVVTAIA-TPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRL 279 A V+RGH V A P+ S + S S D + +W+L+ TS + R Sbjct: 167 AVVLRGHESEVFICAWNPV--SDLLASGSGDSTARIWNLSE-----NSTSGSTQLVLRHC 219 Query: 280 TGHG-------HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVA 438 G V + +S+G +GS+DG R+W G H+ + ++ Sbjct: 220 IREGGQDVPSNKDVTSLDWNSEGTLLATGSYDGFARIW-TKDGNLASTLGQHKGPIFALK 278 Query: 439 FSIDNRQIVSASRDRTIKLWNT-LGECK 519 ++ I+SA D+T +W+ GE K Sbjct: 279 WNKKGNFILSAGVDKTTIIWDAHTGEAK 306 Score = 38.1 bits (87), Expect = 0.017 Identities = 24/98 (24%), Positives = 41/98 (41%), Gaps = 10/98 (10%) Frame = +1 Query: 265 PFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFS 444 P + GH + V + G S S D L++W + H K++ ++ +S Sbjct: 346 PIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSMKHDTCVHDLQAHNKEIYTIKWS 405 Query: 445 ID---------NRQIVSASRDRTIKLWNT-LGECKYTI 528 N + SAS D T++LW+ G C +T+ Sbjct: 406 PTGPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTL 443 Score = 31.2 bits (69), Expect = 2.0 Identities = 26/103 (25%), Positives = 41/103 (39%), Gaps = 14/103 (13%) Frame = +1 Query: 277 LTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLS---TGVTTRRFVGH----------- 414 L GH V + SGS D R+W+LS T +T+ + H Sbjct: 170 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVPS 229 Query: 415 EKDVLSVAFSIDNRQIVSASRDRTIKLWNTLGECKYTIGGDLG 543 KDV S+ ++ + + + S D ++W G T+G G Sbjct: 230 NKDVTSLDWNSEGTLLATGSYDGFARIWTKDGNLASTLGQHKG 272 Score = 29.3 bits (64), Expect = 7.8 Identities = 18/55 (32%), Positives = 22/55 (40%) Frame = +1 Query: 325 GQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTI 489 G F LS D +WD TG ++F H L V + N S S D I Sbjct: 283 GNFILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQ-SNNTFASCSTDMCI 336
>UTP15_MOUSE (Q8C7V3) U3 small nucleolar RNA-associated protein 15 homolog| (Src-associated protein SAW) Length = 528 Score = 56.2 bits (134), Expect = 6e-08 Identities = 26/60 (43%), Positives = 40/60 (66%) Frame = +1 Query: 322 DGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN 501 DGQ ++GS DG ++L+D++ R+F GH K V +V F+ DN +VS + D T+KLW+ Sbjct: 91 DGQLLVAGSEDGVVQLFDINGRAPLRQFEGHTKAVHTVDFTADNYHVVSGADDYTVKLWD 150 Score = 37.0 bits (84), Expect = 0.037 Identities = 22/80 (27%), Positives = 37/80 (46%), Gaps = 1/80 (1%) Frame = +1 Query: 265 PFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDV-LSVAF 441 P R+ GH V V ++D +SG+ D ++LWD+ F H V A Sbjct: 114 PLRQFEGHTKAVHTVDFTADNYHVVSGADDYTVKLWDIPNSKEILTFKEHSDYVRCGCAS 173 Query: 442 SIDNRQIVSASRDRTIKLWN 501 ++ V+ S D T+K+++ Sbjct: 174 KLNPDLFVTGSYDHTVKIFD 193 Score = 31.6 bits (70), Expect = 1.6 Identities = 23/83 (27%), Positives = 39/83 (46%) Frame = +1 Query: 277 LTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNR 456 L H V + LSS GQ LSGS D +++++ ++ F + +LS+A S + Sbjct: 244 LKNHHKTVTCLCLSSSGQRLLSGSLDRKVKVYSTTSYKVVHSF-DYAASILSLALSHQDE 302 Query: 457 QIVSASRDRTIKLWNTLGECKYT 525 IV + + + + E K T Sbjct: 303 TIVVGMTNGILSVKHRKSEAKKT 325
>WDR71_HUMAN (Q9BRP4) WD-repeat protein 71 (Protein G-16)| Length = 392 Score = 55.8 bits (133), Expect = 8e-08 Identities = 39/128 (30%), Positives = 53/128 (41%), Gaps = 8/128 (6%) Frame = +1 Query: 175 VSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSWD 354 VSSS D ++ +W +N G R L GH V G LSG D Sbjct: 108 VSSSTDGTMKIWQASN------------GELRRVLEGHVFDVNCCRFFPSGLVVLSGGMD 155 Query: 355 GELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN--------TLG 510 +L++W F GH+ +L A R +VSASRD T +LW+ L Sbjct: 156 AQLKIWSAEDASCVVTFKGHKGGILDTAIVDRGRNVVSASRDGTARLWDCGRSACLGVLA 215 Query: 511 ECKYTIGG 534 +C +I G Sbjct: 216 DCGSSING 223 Score = 46.6 bits (109), Expect = 5e-05 Identities = 29/105 (27%), Positives = 47/105 (44%), Gaps = 2/105 (1%) Frame = +1 Query: 238 QDTSSEYGVPFRRLTG-HGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGH 414 ++ SS++ P+ + H + + +SS G +S S DG +++W S G R GH Sbjct: 74 ENASSKFLAPYTTFSRIHTKSITCLDISSRGGLGVSSSTDGTMKIWQASNGELRRVLEGH 133 Query: 415 EKDVLSVAFSIDNRQIVSASRDRTIKLWNTL-GECKYTIGGDLGG 546 DV F ++S D +K+W+ C T G GG Sbjct: 134 VFDVNCCRFFPSGLVVLSGGMDAQLKIWSAEDASCVVTFKGHKGG 178
>YJL2_YEAST (P47025) Hypothetical 80.0 kDa Trp-Asp repeats-containing protein| in ASF1-CCT7 intergenic region Length = 714 Score = 55.8 bits (133), Expect = 8e-08 Identities = 42/137 (30%), Positives = 67/137 (48%), Gaps = 10/137 (7%) Frame = +1 Query: 121 HNDVVTAIATPIDNSPFIVSSSRDKSLLVWDL-------TNPIQATQDTSSEYGVPFRR- 276 H D VTA++ +D S F+VS S+D+++ WDL T + ++ V + Sbjct: 501 HTDEVTALS--LDPS-FLVSGSQDRTIRQWDLRSGKCLQTIDLSFANVLTTSTNVDLSKS 557 Query: 277 --LTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSID 450 LT L S +G+ DG +RLWDL +G R GH + S+ F D Sbjct: 558 TLLTQRNERPSIGALQSFDAALATGTKDGVVRLWDLRSGKVIRTLKGHTDAITSLKF--D 615 Query: 451 NRQIVSASRDRTIKLWN 501 + +V+ S DRT+++W+ Sbjct: 616 SACLVTGSYDRTVRIWD 632 Score = 41.2 bits (95), Expect = 0.002 Identities = 40/160 (25%), Positives = 66/160 (41%), Gaps = 20/160 (12%) Frame = +1 Query: 109 VMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 +M H+D +T + + D ++ +WDL+ Q+ E L GH Sbjct: 393 IMSTHDDFLTCLDFDAPFGTLCTAGYLDHTVKIWDLSK-----QNKIGE-------LAGH 440 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDLS------------TGVT-------TRRFVG 411 + + ++ D ++G D L+LW+L+ T T F Sbjct: 441 LATINCMQINRDYGTLVTGGRDAALKLWNLNLAQQLYQETQNLTSPTNHIDSPCVHTFEA 500 Query: 412 HEKDVLSVAFSIDNRQIVSASRDRTIKLWN-TLGECKYTI 528 H +V A S+D +VS S+DRTI+ W+ G+C TI Sbjct: 501 HTDEV--TALSLDPSFLVSGSQDRTIRQWDLRSGKCLQTI 538 Score = 39.3 bits (90), Expect = 0.007 Identities = 32/121 (26%), Positives = 53/121 (43%), Gaps = 6/121 (4%) Frame = +1 Query: 106 GVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRL-- 279 G + GH + + D +V+ RD +L +W+L Q Q+T + P + Sbjct: 435 GELAGHLATINCMQINRDYGT-LVTGGRDAALKLWNLNLAQQLYQETQNLTS-PTNHIDS 492 Query: 280 ----TGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSI 447 T H + LS D F +SGS D +R WDL +G + +VL+ + ++ Sbjct: 493 PCVHTFEAHTDEVTALSLDPSFLVSGSQDRTIRQWDLRSGKCLQTIDLSFANVLTTSTNV 552 Query: 448 D 450 D Sbjct: 553 D 553 Score = 38.1 bits (87), Expect = 0.017 Identities = 27/100 (27%), Positives = 46/100 (46%) Frame = +1 Query: 172 IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSW 351 + + ++D + +WDL + G R L GH + L D ++GS+ Sbjct: 579 LATGTKDGVVRLWDLRS------------GKVIRTLKGHTDAITS--LKFDSACLVTGSY 624 Query: 352 DGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSA 471 D +R+WDL TG+ +F + VLS+ +N +V A Sbjct: 625 DRTVRIWDLRTGL-LNKFHAYSAPVLSLDLFQENAAVVVA 663
>COPB2_MOUSE (O55029) Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP)| (p102) Length = 905 Score = 55.8 bits (133), Expect = 8e-08 Identities = 40/147 (27%), Positives = 67/147 (45%), Gaps = 5/147 (3%) Frame = +1 Query: 109 VMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 + H+D + IA PFI++SS D + +WD +Q GH Sbjct: 94 MFEAHSDYIRCIAVH-PTQPFILTSSDDMLIKLWDWDKKWSCSQ-----------VFEGH 141 Query: 289 GHFVQDVVLS--SDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAF--SIDNR 456 H+V +V++ + QFA S S D +++W L + GHEK V + + D Sbjct: 142 THYVMQIVINPKDNNQFA-SASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGGDKP 200 Query: 457 QIVSASRDRTIKLWNTLGE-CKYTIGG 534 ++S + DR +K+W+ + C T+ G Sbjct: 201 YLISGADDRLVKIWDYQNKTCVQTLEG 227 Score = 50.1 bits (118), Expect = 4e-06 Identities = 36/135 (26%), Positives = 60/135 (44%), Gaps = 3/135 (2%) Frame = +1 Query: 109 VMRGHNDVVTAIA-TPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTG 285 V GH V I P DN+ F S+S D+++ VW L + P L G Sbjct: 137 VFEGHTHYVMQIVINPKDNNQF-ASASLDRTIKVWQLGS------------SSPNFTLEG 183 Query: 286 HGHFVQ--DVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQ 459 H V D D + +SG+ D +++WD + GH ++V +F + Sbjct: 184 HEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTCVQTLEGHAQNVSCASFHPELPI 243 Query: 460 IVSASRDRTIKLWNT 504 I++ S D T+++W++ Sbjct: 244 IITGSEDGTVRIWHS 258 Score = 32.7 bits (73), Expect = 0.70 Identities = 18/75 (24%), Positives = 32/75 (42%) Frame = +1 Query: 160 NSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFAL 339 + P+++S + D+ + +WD N + L GH V + + Sbjct: 198 DKPYLISGADDRLVKIWDYQNKTCV------------QTLEGHAQNVSCASFHPELPIII 245 Query: 340 SGSWDGELRLWDLST 384 +GS DG +R+W ST Sbjct: 246 TGSEDGTVRIWHSST 260
>COPB2_HUMAN (P35606) Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP)| (p102) Length = 905 Score = 55.8 bits (133), Expect = 8e-08 Identities = 40/147 (27%), Positives = 67/147 (45%), Gaps = 5/147 (3%) Frame = +1 Query: 109 VMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 + H+D + IA PFI++SS D + +WD +Q GH Sbjct: 93 MFEAHSDYIRCIAVH-PTQPFILTSSDDMLIKLWDWDKKWSCSQ-----------VFEGH 140 Query: 289 GHFVQDVVLS--SDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAF--SIDNR 456 H+V +V++ + QFA S S D +++W L + GHEK V + + D Sbjct: 141 THYVMQIVINPKDNNQFA-SASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGGDKP 199 Query: 457 QIVSASRDRTIKLWNTLGE-CKYTIGG 534 ++S + DR +K+W+ + C T+ G Sbjct: 200 YLISGADDRLVKIWDYQNKTCVQTLEG 226 Score = 50.1 bits (118), Expect = 4e-06 Identities = 36/135 (26%), Positives = 60/135 (44%), Gaps = 3/135 (2%) Frame = +1 Query: 109 VMRGHNDVVTAIA-TPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTG 285 V GH V I P DN+ F S+S D+++ VW L + P L G Sbjct: 136 VFEGHTHYVMQIVINPKDNNQF-ASASLDRTIKVWQLGS------------SSPNFTLEG 182 Query: 286 HGHFVQ--DVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQ 459 H V D D + +SG+ D +++WD + GH ++V +F + Sbjct: 183 HEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTCVQTLEGHAQNVSCASFHPELPI 242 Query: 460 IVSASRDRTIKLWNT 504 I++ S D T+++W++ Sbjct: 243 IITGSEDGTVRIWHS 257 Score = 32.7 bits (73), Expect = 0.70 Identities = 18/75 (24%), Positives = 32/75 (42%) Frame = +1 Query: 160 NSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFAL 339 + P+++S + D+ + +WD N + L GH V + + Sbjct: 197 DKPYLISGADDRLVKIWDYQNKTCV------------QTLEGHAQNVSCASFHPELPIII 244 Query: 340 SGSWDGELRLWDLST 384 +GS DG +R+W ST Sbjct: 245 TGSEDGTVRIWHSST 259
>COPB2_BOVIN (P35605) Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP)| (p102) Length = 905 Score = 55.8 bits (133), Expect = 8e-08 Identities = 40/147 (27%), Positives = 67/147 (45%), Gaps = 5/147 (3%) Frame = +1 Query: 109 VMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 + H+D + IA PFI++SS D + +WD +Q GH Sbjct: 93 MFEAHSDYIRCIAVH-PTQPFILTSSDDMLIKLWDWDKKWSCSQ-----------VFEGH 140 Query: 289 GHFVQDVVLS--SDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAF--SIDNR 456 H+V +V++ + QFA S S D +++W L + GHEK V + + D Sbjct: 141 THYVMQIVINPKDNNQFA-SASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGGDKP 199 Query: 457 QIVSASRDRTIKLWNTLGE-CKYTIGG 534 ++S + DR +K+W+ + C T+ G Sbjct: 200 YLISGADDRLVKIWDYQNKTCVQTLEG 226 Score = 50.1 bits (118), Expect = 4e-06 Identities = 36/135 (26%), Positives = 60/135 (44%), Gaps = 3/135 (2%) Frame = +1 Query: 109 VMRGHNDVVTAIA-TPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTG 285 V GH V I P DN+ F S+S D+++ VW L + P L G Sbjct: 136 VFEGHTHYVMQIVINPKDNNQF-ASASLDRTIKVWQLGS------------SSPNFTLEG 182 Query: 286 HGHFVQ--DVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQ 459 H V D D + +SG+ D +++WD + GH ++V +F + Sbjct: 183 HEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTCVQTLEGHAQNVSCASFHPELPI 242 Query: 460 IVSASRDRTIKLWNT 504 I++ S D T+++W++ Sbjct: 243 IITGSEDGTVRIWHS 257 Score = 32.7 bits (73), Expect = 0.70 Identities = 18/75 (24%), Positives = 32/75 (42%) Frame = +1 Query: 160 NSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFAL 339 + P+++S + D+ + +WD N + L GH V + + Sbjct: 197 DKPYLISGADDRLVKIWDYQNKTCV------------QTLEGHAQNVSCASFHPELPIII 244 Query: 340 SGSWDGELRLWDLST 384 +GS DG +R+W ST Sbjct: 245 TGSEDGTVRIWHSST 259
>WSB1_MOUSE (O54927) WD repeat and SOCS box-containing protein 1 (WSB-1)| Length = 421 Score = 55.8 bits (133), Expect = 8e-08 Identities = 36/127 (28%), Positives = 57/127 (44%) Frame = +1 Query: 121 HNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFV 300 H ++V + D S +VS+SRDK+L VWDL + G + L H ++V Sbjct: 169 HIEMVRDLTFAPDGSLLLVSASRDKTLRVWDLKDD-----------GNMVKVLRAHQNWV 217 Query: 301 QDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRD 480 S D S + LW++ R+ GH DV++ FS D + +AS D Sbjct: 218 YSCAFSPDCSMLCSVGASKAVFLWNMDKYTMIRKLEGHHHDVVACDFSPDGALLATASYD 277 Query: 481 RTIKLWN 501 + +W+ Sbjct: 278 TRVYVWD 284 Score = 35.8 bits (81), Expect = 0.083 Identities = 34/134 (25%), Positives = 55/134 (41%), Gaps = 6/134 (4%) Frame = +1 Query: 121 HNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLT------ 282 H+DVV +P + + ++S D + VWD N D E+G F T Sbjct: 256 HHDVVACDFSP--DGALLATASYDTRVYVWDPHNG-----DLLMEFGHLFPSPTPIFAGG 308 Query: 283 GHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQI 462 + +V+ V S DG S + D +R W + + V + L AFS D + Sbjct: 309 ANDRWVRAVSFSHDGLHVASLADDKMVRFWRIDEDCPVQ--VAPLSNGLCCAFSTDGSVL 366 Query: 463 VSASRDRTIKLWNT 504 + + D ++ W T Sbjct: 367 AAGTHDGSVYFWAT 380
>HIR1_YEAST (P32479) Histone transcription regulator 1| Length = 788 Score = 55.8 bits (133), Expect = 8e-08 Identities = 39/146 (26%), Positives = 69/146 (47%), Gaps = 7/146 (4%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQ-----DTSSEYGVPFRR 276 M H +T + D ++ S S D+ LL+W L Q++Q + E+ +R Sbjct: 23 MSRHTGSITCVKFSPDGK-YLASGSDDRILLIWALDEE-QSSQPAFGSEHEREHWTVRKR 80 Query: 277 LTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNR 456 L H + +QD+ + D ++ D + +W+ ST +RF H+ V V F N+ Sbjct: 81 LVAHDNDIQDICWAPDSSILVTVGLDRSVIVWNGSTFEKLKRFDVHQSLVKGVVFDPANK 140 Query: 457 QIVSASRDRTIKL--WNTLGECKYTI 528 + S DRT+K+ ++ G+ +TI Sbjct: 141 YFATTSDDRTMKIFRYHKTGDISFTI 166 Score = 40.4 bits (93), Expect = 0.003 Identities = 28/112 (25%), Positives = 49/112 (43%), Gaps = 16/112 (14%) Frame = +1 Query: 214 LTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVT 393 LT I QD +P ++ H + V S DG++ SGS D L +W L + Sbjct: 6 LTPEIPLPQDLQ----MPLCSMSRHTGSITCVKFSPDGKYLASGSDDRILLIWALDEEQS 61 Query: 394 T----------------RRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN 501 + +R V H+ D+ + ++ D+ +V+ DR++ +WN Sbjct: 62 SQPAFGSEHEREHWTVRKRLVAHDNDIQDICWAPDSSILVTVGLDRSVIVWN 113
>WDR57_PONPY (Q5RF51) WD-repeat protein 57| Length = 357 Score = 55.5 bits (132), Expect = 1e-07 Identities = 40/143 (27%), Positives = 62/143 (43%), Gaps = 9/143 (6%) Frame = +1 Query: 103 AGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLT-NPIQATQDTSSEYGVPFRRL 279 A + N T D S I+S D + VWDL N + T + Sbjct: 185 AAIQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYT-------------M 231 Query: 280 TGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFV--------GHEKDVLSV 435 GH V + LSS+G + LS + D +R+WD+ R V EK++L Sbjct: 232 RGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRC 291 Query: 436 AFSIDNRQIVSASRDRTIKLWNT 504 ++S D +I + S DR++ +W+T Sbjct: 292 SWSPDGSKIAAGSADRSVCVWDT 314 Score = 48.9 bits (115), Expect = 9e-06 Identities = 39/139 (28%), Positives = 65/139 (46%), Gaps = 4/139 (2%) Frame = +1 Query: 85 QESLVYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGV 264 Q L Y MRGH D VT ++ + S +++S++ D ++ VWD+ P + + Sbjct: 224 QNKLTYT--MRGHADSVTGLSLSSEGS-YLLSNAMDNTVRVWDV-RPFAPKERCVKIF-- 277 Query: 265 PFRRLTGHGHFVQDVVL----SSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLS 432 G+ H + +L S DG +GS D + +WD ++ + GH + Sbjct: 278 -----QGNVHNFEKNLLRCSWSPDGSKIAAGSADRSVCVWDTTSRRILYKLPGHAGSINE 332 Query: 433 VAFSIDNRQIVSASRDRTI 489 VAF D I+SAS D+ + Sbjct: 333 VAFHPDEPIIISASSDKRL 351 Score = 45.4 bits (106), Expect = 1e-04 Identities = 28/132 (21%), Positives = 54/132 (40%), Gaps = 2/132 (1%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNP--IQATQDTSSEYGVPFRRLTG 285 ++GH V + + + S D ++ +WD+ IQ Q+T V F + Sbjct: 147 LKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRKKAAIQTFQNTYQVLAVTFNDTSD 206 Query: 286 HGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIV 465 +SG D ++++WDL T GH V ++ S + ++ Sbjct: 207 Q---------------IISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLSLSSEGSYLL 251 Query: 466 SASRDRTIKLWN 501 S + D T+++W+ Sbjct: 252 SNAMDNTVRVWD 263 Score = 44.3 bits (103), Expect = 2e-04 Identities = 31/115 (26%), Positives = 53/115 (46%), Gaps = 1/115 (0%) Frame = +1 Query: 160 NSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFAL 339 N + S+ D+ +L+W++ D + + L G+ V ++ ++DG Sbjct: 77 NGSTLASAGFDRLILLWNVYG------DCGN-----YATLKGYSGAVMELHYNTDGSMLF 125 Query: 340 SGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIV-SASRDRTIKLWN 501 S S D + +WD TG +R GH V S + Q+V + S D T+KLW+ Sbjct: 126 SASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWD 180 Score = 34.7 bits (78), Expect = 0.18 Identities = 24/97 (24%), Positives = 41/97 (42%), Gaps = 4/97 (4%) Frame = +1 Query: 226 IQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLW----DLSTGVT 393 +QA S P L+GH V +G S +D + LW D T Sbjct: 45 LQAGPPRCSSLQAPIMLLSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCGNYAT 104 Query: 394 TRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNT 504 + G+ V+ + ++ D + SAS D+T+ +W++ Sbjct: 105 LK---GYSGAVMELHYNTDGSMLFSASTDKTVAVWDS 138 Score = 33.9 bits (76), Expect = 0.31 Identities = 15/36 (41%), Positives = 19/36 (52%) Frame = +1 Query: 409 GHEKDVLSVAFSIDNRQIVSASRDRTIKLWNTLGEC 516 GHE +V F + + SA DR I LWN G+C Sbjct: 64 GHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDC 99
>GBB2_DROME (P29829) Guanine nucleotide-binding protein beta subunit 2| Length = 346 Score = 55.5 bits (132), Expect = 1e-07 Identities = 37/128 (28%), Positives = 58/128 (45%) Frame = +1 Query: 130 VVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDV 309 V+T +P N F+ D V+D+ N +S + L G+ F+ Sbjct: 104 VMTVAFSPSGN--FVACGGMDNQCTVYDVNNR------DASGVAKMVKELMGYEGFLSSC 155 Query: 310 VLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTI 489 DG ++GS D ++ WDL GV T F GH D+ ++ S D + ++ S D+T Sbjct: 156 RFLDDGHL-ITGSGDMKICHWDLEKGVKTMDFNGHAGDIAGLSLSPDMKTYITGSVDKTA 214 Query: 490 KLWNTLGE 513 KLW+ E Sbjct: 215 KLWDVREE 222 Score = 48.5 bits (114), Expect = 1e-05 Identities = 30/110 (27%), Positives = 49/110 (44%) Frame = +1 Query: 172 IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSW 351 +++ S D + WDL E GV GH + + LS D + ++GS Sbjct: 163 LITGSGDMKICHWDL------------EKGVKTMDFNGHAGDIAGLSLSPDMKTYITGSV 210 Query: 352 DGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN 501 D +LWD+ + F GH+ DV SV + S S D+T ++++ Sbjct: 211 DKTAKLWDVREEGHKQMFFGHDMDVSSVCYHPSGFGFASCSEDQTARMYD 260 Score = 38.1 bits (87), Expect = 0.017 Identities = 28/127 (22%), Positives = 51/127 (40%) Frame = +1 Query: 118 GHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHF 297 GH+ V+++ F S S D++ ++DL Q Q + F Sbjct: 230 GHDMDVSSVCYHPSGFGF-ASCSEDQTARMYDLRADQQIAQYEPPQKNTGFT-------- 280 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASR 477 LS+ G++ + G +G + WD T GHE + ++ + + S S Sbjct: 281 --SCALSTSGRYLMCGGIEGNVHSWDTMKQRHTGTLSGHENRITCISLCPNGMCLASTSW 338 Query: 478 DRTIKLW 498 D+ ++LW Sbjct: 339 DQQVRLW 345 Score = 34.3 bits (77), Expect = 0.24 Identities = 20/75 (26%), Positives = 34/75 (45%) Frame = +1 Query: 277 LTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNR 456 L GH + V V + D + ++GS DG+L +WD T + V++VAFS Sbjct: 55 LKGHINKVNSVHFAGDSRHCVTGSLDGKLIIWDTWTANKVQIIPLRSAWVMTVAFSPSGN 114 Query: 457 QIVSASRDRTIKLWN 501 + D +++ Sbjct: 115 FVACGGMDNQCTVYD 129
>PEX7_CRIGR (Q8R537) Peroxisomal targeting signal 2 receptor (PTS2 receptor)| (Peroxin-7) Length = 318 Score = 55.1 bits (131), Expect = 1e-07 Identities = 37/120 (30%), Positives = 59/120 (49%), Gaps = 5/120 (4%) Frame = +1 Query: 157 DNSPFIVSSSRDKSLLVWDL---TNPIQATQDTSSE-YGVPFRRLTGHGHFVQDVVLSSD 324 DN +V+ S D SL +WD T P+Q ++ + E Y V + + G Sbjct: 73 DNEHVLVTCSGDGSLQLWDTAKATGPLQVYKEHTQEVYSVDWSQTRGE------------ 120 Query: 325 GQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSID-NRQIVSASRDRTIKLWN 501 Q +SGSWD +++WD + G + F GHE + S +S SAS D+T+++W+ Sbjct: 121 -QLVVSGSWDQTVKVWDPTVGNSLCTFRGHESVIYSTIWSPHIPGCFASASGDQTLRIWD 179
>MORG1_BRARE (Q6DH44) Mitogen-activated protein kinase organizer 1 (MAPK| organizer 1) Length = 315 Score = 55.1 bits (131), Expect = 1e-07 Identities = 33/112 (29%), Positives = 55/112 (49%) Frame = +1 Query: 169 FIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGS 348 ++++ DKSL +W ++ G + +GHG+ V D S D S S Sbjct: 39 YLLTCGSDKSLKLWSVSR------------GTLLKTYSGHGYEVLDADGSYDNSQLCSCS 86 Query: 349 WDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNT 504 D + LWD+++G TR+ GH V V F+ + ++S S D T++ W+T Sbjct: 87 SDKTVILWDVASGQVTRKLRGHAGKVNCVQFNEEATVMLSGSIDGTVRCWDT 138 Score = 52.8 bits (125), Expect = 7e-07 Identities = 25/68 (36%), Positives = 39/68 (57%) Frame = +1 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASR 477 V+ V ++DG + L+ D L+LW +S G + + GH +VL S DN Q+ S S Sbjct: 28 VRAVRFNADGNYLLTCGSDKSLKLWSVSRGTLLKTYSGHGYEVLDADGSYDNSQLCSCSS 87 Query: 478 DRTIKLWN 501 D+T+ LW+ Sbjct: 88 DKTVILWD 95 Score = 35.8 bits (81), Expect = 0.083 Identities = 38/162 (23%), Positives = 62/162 (38%), Gaps = 32/162 (19%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTN----PIQATQDTSSEYGVPFRRL 279 +RGH V + + + ++S S D ++ WD + PIQ + S+ G+ ++ Sbjct: 105 LRGHAGKVNCVQFN-EEATVMLSGSIDGTVRCWDTRSRRMEPIQILDE--SQDGISSLKV 161 Query: 280 TGH--------------------------GHFVQDVVLSSDGQFALSGSWDGELRLWDLS 381 + H G + V S DGQ LS S D +RL D S Sbjct: 162 SEHELLTGSVDGRVRRYDLRMGQLQVDYIGSPITCVCFSRDGQCTLSSSLDSTVRLLDKS 221 Query: 382 TGVTTRRFVGHEKD--VLSVAFSIDNRQIVSASRDRTIKLWN 501 TG + GH L + + ++S S D + W+ Sbjct: 222 TGEMLGEYSGHVNKGYKLDCCLTDKDTHVLSCSEDGHVYYWD 263
>PLRG1_RAT (Q9WUC8) Pleiotropic regulator 1| Length = 514 Score = 55.1 bits (131), Expect = 1e-07 Identities = 38/140 (27%), Positives = 58/140 (41%), Gaps = 1/140 (0%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 + GH V + SP++ S DK + WDL EY R GH Sbjct: 242 LTGHISTVRGVIVST-RSPYLFSCGEDKQVKCWDL------------EYNKVIRHYHGHL 288 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSA 471 V + L ++ S D R+WD+ T + GH V +V QI++ Sbjct: 289 SAVYGLDLHPTIDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITG 348 Query: 472 SRDRTIKLWNTL-GECKYTI 528 S D TI+LW+ + G+ + T+ Sbjct: 349 SHDTTIRLWDLVAGKTRVTL 368 Score = 46.6 bits (109), Expect = 5e-05 Identities = 21/78 (26%), Positives = 41/78 (52%) Frame = +1 Query: 268 FRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSI 447 +R ++GH +V+ + + Q+ ++GS D +++WDL++G GH V V S Sbjct: 197 YRVISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVST 256 Query: 448 DNRQIVSASRDRTIKLWN 501 + + S D+ +K W+ Sbjct: 257 RSPYLFSCGEDKQVKCWD 274 Score = 43.9 bits (102), Expect = 3e-04 Identities = 39/138 (28%), Positives = 59/138 (42%), Gaps = 3/138 (2%) Frame = +1 Query: 94 LVYAGVMRGHNDVVTAIATPIDNSPFI---VSSSRDKSLLVWDLTNPIQATQDTSSEYGV 264 L Y V+R ++ ++A+ +D P I V+ SRD + +WD+ Sbjct: 275 LEYNKVIRHYHGHLSAVYG-LDLHPTIDVLVTCSRDSTARIWDVRTKASV---------- 323 Query: 265 PFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFS 444 L+GH + V V + ++GS D +RLWDL G T H+K V +V Sbjct: 324 --HTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVRAVVLH 381 Query: 445 IDNRQIVSASRDRTIKLW 498 + S S D IK W Sbjct: 382 PLHYTFASGSPD-NIKQW 398
>PLRG1_HUMAN (O43660) Pleiotropic regulator 1| Length = 514 Score = 55.1 bits (131), Expect = 1e-07 Identities = 38/140 (27%), Positives = 58/140 (41%), Gaps = 1/140 (0%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 + GH V + SP++ S DK + WDL EY R GH Sbjct: 242 LTGHISTVRGVIVST-RSPYLFSCGEDKQVKCWDL------------EYNKVIRHYHGHL 288 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSA 471 V + L ++ S D R+WD+ T + GH V +V QI++ Sbjct: 289 SAVYGLDLHPTIDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITG 348 Query: 472 SRDRTIKLWNTL-GECKYTI 528 S D TI+LW+ + G+ + T+ Sbjct: 349 SHDTTIRLWDLVAGKTRVTL 368 Score = 46.6 bits (109), Expect = 5e-05 Identities = 21/78 (26%), Positives = 41/78 (52%) Frame = +1 Query: 268 FRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSI 447 +R ++GH +V+ + + Q+ ++GS D +++WDL++G GH V V S Sbjct: 197 YRVISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVST 256 Query: 448 DNRQIVSASRDRTIKLWN 501 + + S D+ +K W+ Sbjct: 257 RSPYLFSCGEDKQVKCWD 274 Score = 44.7 bits (104), Expect = 2e-04 Identities = 39/138 (28%), Positives = 59/138 (42%), Gaps = 3/138 (2%) Frame = +1 Query: 94 LVYAGVMRGHNDVVTAIATPIDNSPFI---VSSSRDKSLLVWDLTNPIQATQDTSSEYGV 264 L Y V+R ++ ++A+ +D P I V+ SRD + +WD+ Sbjct: 275 LEYNKVIRHYHGHLSAVYG-LDLHPTIDVLVTCSRDSTARIWDVRTKASV---------- 323 Query: 265 PFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFS 444 L+GH + V V + ++GS D +RLWDL G T H+K V +V Sbjct: 324 --HTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVRAVVLH 381 Query: 445 IDNRQIVSASRDRTIKLW 498 + S S D IK W Sbjct: 382 PRHYTFASGSPD-NIKQW 398
>NUDF_EMENI (Q00664) Nuclear migration protein nudF| Length = 444 Score = 55.1 bits (131), Expect = 1e-07 Identities = 37/111 (33%), Positives = 55/111 (49%), Gaps = 2/111 (1%) Frame = +1 Query: 172 IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDV-VLSSDGQFALSGS 348 + S S D ++ +WD S +Y R L+GH H V V L+S+ +S S Sbjct: 173 LASCSSDLTIKLWD----------PSKDYA-NIRTLSGHDHSVSSVRFLTSNDNHLISAS 221 Query: 349 WDGELRLWDLSTGVTTRRFVGH-EKDVLSVAFSIDNRQIVSASRDRTIKLW 498 DG LR+WD+STG + E + V+ S D + +VS RD+ I +W Sbjct: 222 RDGTLRIWDVSTGFCVKVIKSATESWIRDVSPSFDGKWLVSGGRDQAITVW 272 Score = 52.4 bits (124), Expect = 9e-07 Identities = 38/168 (22%), Positives = 71/168 (42%), Gaps = 23/168 (13%) Frame = +1 Query: 100 YAGV--MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFR 273 YA + + GH+ V+++ N ++S+SRD +L +WD++ S+ Sbjct: 191 YANIRTLSGHDHSVSSVRFLTSNDNHLISASRDGTLRIWDVSTGFCVKVIKSATES---- 246 Query: 274 RLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAF---- 441 +++DV S DG++ +SG D + +W++S+ +GHE + F Sbjct: 247 -------WIRDVSPSFDGKWLVSGGRDQAITVWEVSSAEPKAALLGHENFIECCVFAPPA 299 Query: 442 -----------------SIDNRQIVSASRDRTIKLWNTLGECKYTIGG 534 + + + +RD+TIKLW G T+ G Sbjct: 300 SYEHLATLAGLKKPPPATSSCEFVATGARDKTIKLWEARGRLIKTLHG 347 Score = 47.4 bits (111), Expect = 3e-05 Identities = 41/135 (30%), Positives = 58/135 (42%), Gaps = 5/135 (3%) Frame = +1 Query: 112 MRGHNDVVTAIAT-PIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 + H D VT +A P+ S + S S D ++ +WD E G R L GH Sbjct: 110 LTSHRDAVTCVAFHPVFTS--LASGSEDCTIKIWDW------------ELGEIERTLKGH 155 Query: 289 GHFVQDVVLSSDGQFALSGSWDGEL--RLWDLSTGVTT-RRFVGHEKDVLSVAFSIDN-R 456 V + L S +L +LWD S R GH+ V SV F N Sbjct: 156 IRGVSGLDYGGQKGNTLLASCSSDLTIKLWDPSKDYANIRTLSGHDHSVSSVRFLTSNDN 215 Query: 457 QIVSASRDRTIKLWN 501 ++SASRD T+++W+ Sbjct: 216 HLISASRDGTLRIWD 230 Score = 42.7 bits (99), Expect = 7e-04 Identities = 30/139 (21%), Positives = 60/139 (43%), Gaps = 21/139 (15%) Frame = +1 Query: 148 TPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLS--- 318 +P + ++VS RD+++ VW++++ P L GH +F++ V + Sbjct: 252 SPSFDGKWLVSGGRDQAITVWEVSS------------AEPKAALLGHENFIECCVFAPPA 299 Query: 319 ------------------SDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFS 444 S +F +G+ D ++LW+ + G + GH+ V + F Sbjct: 300 SYEHLATLAGLKKPPPATSSCEFVATGARDKTIKLWE-ARGRLIKTLHGHDNWVRGLVFH 358 Query: 445 IDNRQIVSASRDRTIKLWN 501 + + S S D+TI+ W+ Sbjct: 359 PGGKYLFSVSDDKTIRCWD 377 Score = 37.0 bits (84), Expect = 0.037 Identities = 20/71 (28%), Positives = 35/71 (49%) Frame = +1 Query: 169 FIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGS 348 F+ + +RDK++ +W+ + T L GH ++V+ +V G++ S S Sbjct: 322 FVATGARDKTIKLWEARGRLIKT-------------LHGHDNWVRGLVFHPGGKYLFSVS 368 Query: 349 WDGELRLWDLS 381 D +R WDLS Sbjct: 369 DDKTIRCWDLS 379 Score = 32.3 bits (72), Expect = 0.92 Identities = 19/53 (35%), Positives = 26/53 (49%), Gaps = 1/53 (1%) Frame = +1 Query: 391 TTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN-TLGECKYTIGGDLGG 546 +T H V VAF + S S D TIK+W+ LGE + T+ G + G Sbjct: 106 STHTLTSHRDAVTCVAFHPVFTSLASGSEDCTIKIWDWELGEIERTLKGHIRG 158
>TBL2_MOUSE (Q9R099) Transducin beta-like 2 protein| Length = 442 Score = 55.1 bits (131), Expect = 1e-07 Identities = 41/126 (32%), Positives = 64/126 (50%), Gaps = 5/126 (3%) Frame = +1 Query: 157 DNSPFIVSSSRDKSLLVWDLTNPIQATQDTS---SEYGV--PFRRLTGHGHFVQDVVLSS 321 D FI+++S D ++L+W+L + +T +T+ + + V P R G F DV + Sbjct: 194 DTGKFIMTASSDTTVLIWNLKGQVLSTINTNQMNNSHAVISPCSRFVGSCGFTPDVKVW- 252 Query: 322 DGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN 501 + F G + LR ++L GH V S AFS D+R++ S S+D T KLW+ Sbjct: 253 EVCFGKKGEFQEVLRAFELK---------GHSASVHSFAFSNDSRRMASVSKDGTWKLWD 303 Query: 502 TLGECK 519 T E K Sbjct: 304 TDVEYK 309
>PLRG1_MOUSE (Q922V4) Pleiotropic regulator 1| Length = 513 Score = 55.1 bits (131), Expect = 1e-07 Identities = 38/140 (27%), Positives = 58/140 (41%), Gaps = 1/140 (0%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 + GH V + SP++ S DK + WDL EY R GH Sbjct: 241 LTGHISTVRGVIVST-RSPYLFSCGEDKQVKCWDL------------EYNKVIRHYHGHL 287 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSA 471 V + L ++ S D R+WD+ T + GH V +V QI++ Sbjct: 288 SAVYGLDLHPTLDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITG 347 Query: 472 SRDRTIKLWNTL-GECKYTI 528 S D TI+LW+ + G+ + T+ Sbjct: 348 SHDTTIRLWDLVAGKTRVTL 367 Score = 46.6 bits (109), Expect = 5e-05 Identities = 21/78 (26%), Positives = 41/78 (52%) Frame = +1 Query: 268 FRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSI 447 +R ++GH +V+ + + Q+ ++GS D +++WDL++G GH V V S Sbjct: 196 YRVISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVST 255 Query: 448 DNRQIVSASRDRTIKLWN 501 + + S D+ +K W+ Sbjct: 256 RSPYLFSCGEDKQVKCWD 273 Score = 42.0 bits (97), Expect = 0.001 Identities = 38/138 (27%), Positives = 58/138 (42%), Gaps = 3/138 (2%) Frame = +1 Query: 94 LVYAGVMRGHNDVVTAIATPIDNSP---FIVSSSRDKSLLVWDLTNPIQATQDTSSEYGV 264 L Y V+R ++ ++A+ +D P +V+ SRD + +WD+ Sbjct: 274 LEYNKVIRHYHGHLSAVYG-LDLHPTLDVLVTCSRDSTARIWDVRTKASV---------- 322 Query: 265 PFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFS 444 L+GH + V V + ++GS D +RLWDL G T H+K V +V Sbjct: 323 --HTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVRAVVLH 380 Query: 445 IDNRQIVSASRDRTIKLW 498 S S D IK W Sbjct: 381 PLLYTFASGSPD-NIKQW 397
>COPB2_RAT (O35142) Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP)| (p102) Length = 904 Score = 55.1 bits (131), Expect = 1e-07 Identities = 37/135 (27%), Positives = 62/135 (45%), Gaps = 4/135 (2%) Frame = +1 Query: 109 VMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 + H+D + IA PFI++SS D + +WD +Q GH Sbjct: 93 MFEAHSDYIRCIAVH-PTQPFILTSSDDMLIKLWDWDKKWSCSQ-----------VFEGH 140 Query: 289 GHFVQDVVLS--SDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAF--SIDNR 456 H+V +V++ + QFA S S D +++W L + GHEK V + + D Sbjct: 141 THYVMQIVINPKDNNQFA-SASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGGDKP 199 Query: 457 QIVSASRDRTIKLWN 501 ++S + DR +K+W+ Sbjct: 200 YLISGADDRLVKIWD 214 Score = 48.1 bits (113), Expect = 2e-05 Identities = 36/135 (26%), Positives = 59/135 (43%), Gaps = 3/135 (2%) Frame = +1 Query: 109 VMRGHNDVVTAIA-TPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTG 285 V GH V I P DN+ F S+S D+++ VW L + P L G Sbjct: 136 VFEGHTHYVMQIVINPKDNNQF-ASASLDRTIKVWQLGS------------SSPNFTLEG 182 Query: 286 HGHFVQ--DVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQ 459 H V D D + +SG+ D +++WD + GH ++V F + Sbjct: 183 HEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTCVQTPEGHAQNVSCATFHPELPI 242 Query: 460 IVSASRDRTIKLWNT 504 I++ S D T+++W++ Sbjct: 243 IITGSEDGTVRIWHS 257 Score = 31.6 bits (70), Expect = 1.6 Identities = 18/77 (23%), Positives = 33/77 (42%), Gaps = 2/77 (2%) Frame = +1 Query: 160 NSPFIVSSSRDKSLLVWDLTNP--IQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQF 333 + P+++S + D+ + +WD N +Q + GH V + Sbjct: 197 DKPYLISGADDRLVKIWDYQNKTCVQTPE--------------GHAQNVSCATFHPELPI 242 Query: 334 ALSGSWDGELRLWDLST 384 ++GS DG +R+W ST Sbjct: 243 IITGSEDGTVRIWHSST 259
>POF11_SCHPO (Q09855) F-box/WD-repeat protein pof11| Length = 506 Score = 54.7 bits (130), Expect = 2e-07 Identities = 39/131 (29%), Positives = 65/131 (49%) Frame = +1 Query: 109 VMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 V+RGH V ++ + IV++S D++L WD+T G R + H Sbjct: 342 VLRGHLASVNSVQYS-SKTGLIVTASSDRTLRTWDITT------------GHCIRII--H 386 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVS 468 H +G+F +SGS D +R+++ S+G R GHE + +V F ++ +IVS Sbjct: 387 AHQRGIACAQYNGKFIVSGSSDLTIRIFEASSGKLLRMLQGHEDLIRTVRF--NDEKIVS 444 Query: 469 ASRDRTIKLWN 501 D T+++WN Sbjct: 445 GGYDGTVRIWN 455 Score = 54.3 bits (129), Expect = 2e-07 Identities = 40/129 (31%), Positives = 60/129 (46%), Gaps = 2/129 (1%) Frame = +1 Query: 118 GHNDVVTAIATPIDNSPFIVSSSRDKSLLVW--DLTNPIQATQDTSSEYGVPFRRLTGHG 291 GH D V + + +I+SSSRD + VW D T+P +A L GH Sbjct: 301 GHTDNVLGVVV---SENYIISSSRDHTARVWRLDATSPAEACMHV----------LRGHL 347 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSA 471 V V SS ++ S D LR WD++TG R H++ + + + + IVS Sbjct: 348 ASVNSVQYSSKTGLIVTASSDRTLRTWDITTGHCIRIIHAHQRGIACAQY--NGKFIVSG 405 Query: 472 SRDRTIKLW 498 S D TI+++ Sbjct: 406 SSDLTIRIF 414 Score = 45.4 bits (106), Expect = 1e-04 Identities = 29/109 (26%), Positives = 49/109 (44%) Frame = +1 Query: 172 IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSW 351 +VS S+D+++ VWD+ + +L GH V + +SGS Sbjct: 234 MVSGSKDRTVSVWDVNSRFI------------LYKLYGHSGSVLCLDFCRRRNLLVSGSS 281 Query: 352 DGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLW 498 D + +WD + + GH +VL V + I+S+SRD T ++W Sbjct: 282 DSTIIIWDWQNRRPLKVYFGHTDNVLGVV--VSENYIISSSRDHTARVW 328 Score = 42.7 bits (99), Expect = 7e-04 Identities = 27/114 (23%), Positives = 54/114 (47%) Frame = +1 Query: 160 NSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFAL 339 N FIVS S D ++ +++ ++ G R L GH ++ V + + + Sbjct: 398 NGKFIVSGSSDLTIRIFEASS------------GKLLRMLQGHEDLIRTVRFNDEK--IV 443 Query: 340 SGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN 501 SG +DG +R+W+ +TG + + ++ D+R+I++ + I +WN Sbjct: 444 SGGYDGTVRIWNFNTG-EQHCVLHNSRNSRVFGLQFDHRRIIACTHSSEILVWN 496 Score = 39.3 bits (90), Expect = 0.007 Identities = 19/60 (31%), Positives = 31/60 (51%) Frame = +1 Query: 322 DGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN 501 D + +SGS D + +WD+++ + GH VL + F +VS S D TI +W+ Sbjct: 230 DDEIMVSGSKDRTVSVWDVNSRFILYKLYGHSGSVLCLDFCRRRNLLVSGSSDSTIIIWD 289
>GBB4_RAT (O35353) Guanine nucleotide-binding protein beta subunit 4| (Transducin beta chain 4) Length = 339 Score = 54.7 bits (130), Expect = 2e-07 Identities = 32/110 (29%), Positives = 52/110 (47%) Frame = +1 Query: 172 IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSW 351 I++SS D + +WD+ Q T TGH V + LS D + +SG+ Sbjct: 156 IITSSGDTTCALWDIETGQQTTT------------FTGHSGDVMSLSLSPDLKTFVSGAC 203 Query: 352 DGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN 501 D +LWD+ G+ + F GH D+ +V+F + S D T +L++ Sbjct: 204 DASSKLWDIRDGMCRQSFTGHISDINAVSFFPSGYAFATGSDDATCRLFD 253 Score = 43.5 bits (101), Expect = 4e-04 Identities = 35/134 (26%), Positives = 60/134 (44%), Gaps = 4/134 (2%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 +RGH + A+ D S +VS+S+D L++WD + T+ + +P R Sbjct: 50 LRGHLAKIYAMHWGYD-SRLLVSASQDGKLIIWD-------SYTTNKMHAIPLR-----S 96 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGV----TTRRFVGHEKDVLSVAFSIDNRQ 459 +V + G + G D +++L T +R GH LS +D+ Q Sbjct: 97 SWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELPGHT-GYLSCCRFLDDGQ 155 Query: 460 IVSASRDRTIKLWN 501 I+++S D T LW+ Sbjct: 156 IITSSGDTTCALWD 169 Score = 35.8 bits (81), Expect = 0.083 Identities = 17/68 (25%), Positives = 29/68 (42%) Frame = +1 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASR 477 + V S G+ L+G D +WD G GH+ V + + D + + S Sbjct: 272 ITSVAFSKSGRLLLAGYDDFNCSVWDALKGGRAGVLAGHDNRVSCLGVTDDGMAVATGSW 331 Query: 478 DRTIKLWN 501 D +++WN Sbjct: 332 DSFLRIWN 339 Score = 33.5 bits (75), Expect = 0.41 Identities = 26/99 (26%), Positives = 46/99 (46%), Gaps = 2/99 (2%) Frame = +1 Query: 85 QESLVYAGVMRGHNDVVTAIATPI--DNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEY 258 QE L+Y+ H++++ I + + +++ D + VWD +A Sbjct: 258 QELLLYS-----HDNIICGITSVAFSKSGRLLLAGYDDFNCSVWDALKGGRA-------- 304 Query: 259 GVPFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWD 375 GV L GH + V + ++ DG +GSWD LR+W+ Sbjct: 305 GV----LAGHDNRVSCLGVTDDGMAVATGSWDSFLRIWN 339
>GBB4_MOUSE (P29387) Guanine nucleotide-binding protein beta subunit 4| (Transducin beta chain 4) Length = 339 Score = 54.7 bits (130), Expect = 2e-07 Identities = 32/110 (29%), Positives = 52/110 (47%) Frame = +1 Query: 172 IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSW 351 I++SS D + +WD+ Q T TGH V + LS D + +SG+ Sbjct: 156 IITSSGDTTCALWDIETGQQTTT------------FTGHSGDVMSLSLSPDLKTFVSGAC 203 Query: 352 DGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN 501 D +LWD+ G+ + F GH D+ +V+F + S D T +L++ Sbjct: 204 DASSKLWDIRDGMCRQSFTGHISDINAVSFFPSGYAFATGSDDATCRLFD 253 Score = 43.5 bits (101), Expect = 4e-04 Identities = 35/134 (26%), Positives = 60/134 (44%), Gaps = 4/134 (2%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 +RGH + A+ D S +VS+S+D L++WD + T+ + +P R Sbjct: 50 LRGHLAKIYAMHWGYD-SRLLVSASQDGKLIIWD-------SYTTNKMHAIPLR-----S 96 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGV----TTRRFVGHEKDVLSVAFSIDNRQ 459 +V + G + G D +++L T +R GH LS +D+ Q Sbjct: 97 SWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELPGHT-GYLSCCRFLDDGQ 155 Query: 460 IVSASRDRTIKLWN 501 I+++S D T LW+ Sbjct: 156 IITSSGDTTCALWD 169 Score = 36.2 bits (82), Expect = 0.063 Identities = 17/68 (25%), Positives = 30/68 (44%) Frame = +1 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASR 477 + V S G+ L+G D +WD G + GH+ V + + D + + S Sbjct: 272 ITSVAFSKSGRLLLAGYDDFNCSVWDALKGGRSGVLAGHDNRVSCLGVTDDGMAVATGSW 331 Query: 478 DRTIKLWN 501 D +++WN Sbjct: 332 DSFLRIWN 339 Score = 33.1 bits (74), Expect = 0.54 Identities = 25/99 (25%), Positives = 44/99 (44%), Gaps = 2/99 (2%) Frame = +1 Query: 85 QESLVYAGVMRGHNDVVTAIATPI--DNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEY 258 QE L+Y+ H++++ I + + +++ D + VWD Sbjct: 258 QELLLYS-----HDNIICGITSVAFSKSGRLLLAGYDDFNCSVWDALK--------GGRS 304 Query: 259 GVPFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWD 375 GV L GH + V + ++ DG +GSWD LR+W+ Sbjct: 305 GV----LAGHDNRVSCLGVTDDGMAVATGSWDSFLRIWN 339
>YH92_CAEEL (Q23256) Hypothetical WD-repeat protein ZC302.2| Length = 501 Score = 54.7 bits (130), Expect = 2e-07 Identities = 30/124 (24%), Positives = 58/124 (46%), Gaps = 1/124 (0%) Frame = +1 Query: 160 NSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFAL 339 NS FI S+S D ++ ++D+ + G R + GH ++V + Sbjct: 266 NSQFIASASDDTTVKIFDVIS------------GACLRTMRGHTNYVFCCSFNPQSSLIA 313 Query: 340 SGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNTL-GEC 516 S +D +R+WD TG+ + H + S++++ D + ++S D I++W+ G C Sbjct: 314 SAGFDETVRVWDFKTGLCVKCIPAHSDPITSISYNHDGNTMATSSYDGCIRVWDAASGSC 373 Query: 517 KYTI 528 T+ Sbjct: 374 LKTL 377 Score = 52.0 bits (123), Expect = 1e-06 Identities = 34/131 (25%), Positives = 62/131 (47%), Gaps = 1/131 (0%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 MRGH + V + +S I S+ D+++ VWD G+ + + H Sbjct: 293 MRGHTNYVFCCSFNPQSS-LIASAGFDETVRVWDFKT------------GLCVKCIPAHS 339 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHE-KDVLSVAFSIDNRQIVS 468 + + + DG + S+DG +R+WD ++G + V + V V FS + + ++S Sbjct: 340 DPITSISYNHDGNTMATSSYDGCIRVWDAASGSCLKTLVDTDHAPVTFVCFSPNGKYLLS 399 Query: 469 ASRDRTIKLWN 501 A D ++KLW+ Sbjct: 400 AQLDSSLKLWD 410 Score = 47.8 bits (112), Expect = 2e-05 Identities = 30/111 (27%), Positives = 51/111 (45%) Frame = +1 Query: 169 FIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGS 348 ++ + S DK + VW N + T + L H + D SS+ QF S S Sbjct: 227 YLGTGSADKQIKVW---NTVDMTY---------LQTLASHQLGINDFSWSSNSQFIASAS 274 Query: 349 WDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN 501 D ++++D+ +G R GH V +F+ + I SA D T+++W+ Sbjct: 275 DDTTVKIFDVISGACLRTMRGHTNYVFCCSFNPQSSLIASAGFDETVRVWD 325 Score = 42.4 bits (98), Expect = 9e-04 Identities = 36/131 (27%), Positives = 58/131 (44%), Gaps = 4/131 (3%) Frame = +1 Query: 121 HNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHF- 297 H+D +T+I+ D + + +SS D + VWD + G + L H Sbjct: 338 HSDPITSISYNHDGNT-MATSSYDGCIRVWDAAS------------GSCLKTLVDTDHAP 384 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGH--EKDVLSVAFSID-NRQIVS 468 V V S +G++ LS D L+LWD + + GH +K L S+ + I+S Sbjct: 385 VTFVCFSPNGKYLLSAQLDSSLKLWDPKKAKPLKYYNGHKNKKYCLFANMSVPLGKHIIS 444 Query: 469 ASRDRTIKLWN 501 S D I +W+ Sbjct: 445 GSEDGRILVWS 455 Score = 41.6 bits (96), Expect = 0.002 Identities = 22/89 (24%), Positives = 48/89 (53%), Gaps = 1/89 (1%) Frame = +1 Query: 271 RRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSID 450 + ++GH V + S G++ +GS D ++++W+ + H+ + ++S + Sbjct: 207 KTISGHTKSVSVIKFSYCGKYLGTGSADKQIKVWNTVDMTYLQTLASHQLGINDFSWSSN 266 Query: 451 NRQIVSASRDRTIKLWNTL-GECKYTIGG 534 ++ I SAS D T+K+++ + G C T+ G Sbjct: 267 SQFIASASDDTTVKIFDVISGACLRTMRG 295 Score = 33.9 bits (76), Expect = 0.31 Identities = 29/118 (24%), Positives = 48/118 (40%), Gaps = 5/118 (4%) Frame = +1 Query: 160 NSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSD---GQ 330 N +++S+ D SL +WD P +A P + GH + + + G+ Sbjct: 393 NGKYLLSAQLDSSLKLWD---PKKAK---------PLKYYNGHKNKKYCLFANMSVPLGK 440 Query: 331 FALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSA--SRDRTIKLW 498 +SGS DG + +W + T + GH VL+ I S D I++W Sbjct: 441 HIISGSEDGRILVWSIQTKQIVQILEGHTTPVLATDSHPTLNIIASGGLEPDNVIRIW 498
>TEP1_HUMAN (Q99973) Telomerase protein component 1 (Telomerase-associated| protein 1) (Telomerase protein 1) (p240) (p80 telomerase homolog) Length = 2627 Score = 54.7 bits (130), Expect = 2e-07 Identities = 40/133 (30%), Positives = 60/133 (45%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 +RGH V+ + D + + RD+SLL WD+ P S H Sbjct: 2057 LRGHEGPVSCCSFSTDGGS-LATGGRDRSLLCWDVRTPKTPVLIHSFP--------ACHR 2107 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSA 471 +V + D +S S DG + LWD +G +F+GH+ V +VA +VS Sbjct: 2108 DWVTGCAWTKDN-LLISCSSDGSVGLWDPESGQRLGQFLGHQSAVSAVA--AVEEHVVSV 2164 Query: 472 SRDRTIKLWNTLG 510 SRD T+K+W+ G Sbjct: 2165 SRDGTLKVWDHQG 2177 Score = 43.5 bits (101), Expect = 4e-04 Identities = 37/149 (24%), Positives = 59/149 (39%), Gaps = 9/149 (6%) Frame = +1 Query: 106 GVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTG 285 G GH V+A+A ++ +VS SRD +L VWD GV + Sbjct: 2142 GQFLGHQSAVSAVAAVEEH---VVSVSRDGTLKVWD-------------HQGVELTSIPA 2185 Query: 286 HGHFVQDVVLSSDGQFA---------LSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVA 438 H + + + + A ++ DG RLW T +GH V + A Sbjct: 2186 HSGPISHCAAAMEPRAAGQPGSELLVVTVGLDGATRLWHPLLVCQTHTLLGHSGPVRAAA 2245 Query: 439 FSIDNRQIVSASRDRTIKLWNTLGECKYT 525 S + +++AS D +++LW E T Sbjct: 2246 VSETSGLMLTASEDGSVRLWQVPKEADDT 2274 Score = 36.2 bits (82), Expect = 0.063 Identities = 28/99 (28%), Positives = 42/99 (42%) Frame = +1 Query: 118 GHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHF 297 GH+ V A A + S ++++S D S+ +W + T S V Sbjct: 2236 GHSGPVRAAAVS-ETSGLMLTASEDGSVRLWQVPKEADDTCIPRSSAAVTA--------- 2285 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGH 414 V + DG A+SG+ GEL LW + V T + GH Sbjct: 2286 ---VAWAPDGSMAVSGNQAGELILWQEAKAVATAQAPGH 2321 Score = 35.0 bits (79), Expect = 0.14 Identities = 20/65 (30%), Positives = 30/65 (46%) Frame = +1 Query: 313 LSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIK 492 LS D F + +DG L LWDL G + H+ + S D R + + +K Sbjct: 1727 LSDDTLFLTA--FDGLLELWDLQHGCRVLQTKAHQYQITGCCLSPDCRLLATVCLGGCLK 1784 Query: 493 LWNTL 507 LW+T+ Sbjct: 1785 LWDTV 1789
>GBB3_CANFA (P79147) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 3 (Transducin beta chain 3) Length = 340 Score = 54.7 bits (130), Expect = 2e-07 Identities = 32/122 (26%), Positives = 55/122 (45%) Frame = +1 Query: 172 IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSW 351 IV+SS D + +WD+ Q T GH + +S D + +SG+ Sbjct: 157 IVTSSGDTTCALWDIETGQQKTV------------FVGHTGDCMSLAVSPDFKLFISGAC 204 Query: 352 DGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNTLGECKYTIG 531 D +LWD+ G + F GHE D+ ++ F + I + S D + +L++ + + T Sbjct: 205 DASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELTAY 264 Query: 532 GD 537 D Sbjct: 265 SD 266 Score = 53.9 bits (128), Expect = 3e-07 Identities = 51/176 (28%), Positives = 71/176 (40%), Gaps = 35/176 (19%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDL--TNPIQATQDTSS----------- 252 +RGH + A+ D S +VS+S+D L+VWD TN + A SS Sbjct: 51 LRGHLAKIYAMHWATD-SKLLVSASQDGKLIVWDTYTTNKVHAIPLRSSWVMTCAYAPSG 109 Query: 253 --------------------EYGVPF-RRLTGHGHFVQDVVLSSDGQFALSGSWDGELRL 369 E V R L+ H ++ D S S D L Sbjct: 110 NFVACGGLDNMCSIYSLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTS-SGDTTCAL 168 Query: 370 WDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNTL-GECKYTIGG 534 WD+ TG FVGH D +S+A S D + +S + D + KLW+ G C+ T G Sbjct: 169 WDIETGQQKTVFVGHTGDCMSLAVSPDFKLFISGACDASAKLWDVREGTCRQTFTG 224 Score = 38.1 bits (87), Expect = 0.017 Identities = 32/130 (24%), Positives = 48/130 (36%), Gaps = 2/130 (1%) Frame = +1 Query: 118 GHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLT--NPIQATQDTSSEYGVPFRRLTGHG 291 GH + AI N I + S D S ++DL + A D S G+ Sbjct: 224 GHESDINAICF-FPNGEAICTGSDDASCRLFDLRADQELTAYSDESIICGIT-------- 274 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSA 471 V S G+ +G D +WD G GH+ V + + D + + Sbjct: 275 ----SVAFSLSGRLLFAGYDDFNCNIWDSMKGERVGILSGHDNRVSCLGVTADGMAVATG 330 Query: 472 SRDRTIKLWN 501 S D +K+WN Sbjct: 331 SWDSFLKVWN 340
>WDR12_MOUSE (Q9JJA4) WD-repeat protein 12 (YTM1 homolog)| Length = 423 Score = 54.3 bits (129), Expect = 2e-07 Identities = 45/144 (31%), Positives = 67/144 (46%), Gaps = 15/144 (10%) Frame = +1 Query: 115 RGHNDVVTAIATPIDNSPFIVSSSRDKSLLVW------------DLTNPIQATQDTSSEY 258 RGH V AIA + F S S DK L +W + TN + Q T + Sbjct: 186 RGHAGSVDAIAVDSSGAKFC-SGSWDKMLKIWSTVPTDEEDEMEEATNRPRKKQKTE-QL 243 Query: 259 GV---PFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVL 429 G+ P L+GH + V L SD + S SWD +R+WD+ +G G+ K Sbjct: 244 GLTRTPLVTLSGHTEAISSV-LWSDAEEICSASWDHTIRVWDVESGGLKSTLTGN-KVFN 301 Query: 430 SVAFSIDNRQIVSASRDRTIKLWN 501 +++S +++ S S DR I+LW+ Sbjct: 302 CISYSPLCKRLASGSTDRHIRLWD 325 Score = 36.2 bits (82), Expect = 0.063 Identities = 31/136 (22%), Positives = 57/136 (41%), Gaps = 7/136 (5%) Frame = +1 Query: 121 HNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFV 300 H+D +++I + +I+S S DK+ +W L G + GH V Sbjct: 100 HDDWISSIEGAEE---WILSGSYDKTSRIWSLE-------------GKSIMTIVGHTDVV 143 Query: 301 QDVVLSSDGQFA---LSGSWDGELRLWDLSTGVTTRRFV----GHEKDVLSVAFSIDNRQ 459 +DV + L+ S D + LW+ + + + GH V ++A + Sbjct: 144 KDVAWVKKDSLSCLLLTASMDQTVLLWEWNVEKNKVKALHCCRGHAGSVDAIAVDSSGAK 203 Query: 460 IVSASRDRTIKLWNTL 507 S S D+ +K+W+T+ Sbjct: 204 FCSGSWDKMLKIWSTV 219
>PEX7_MOUSE (P97865) Peroxisomal targeting signal 2 receptor (PTS2 receptor)| (Peroxin-7) Length = 318 Score = 54.3 bits (129), Expect = 2e-07 Identities = 38/131 (29%), Positives = 63/131 (48%), Gaps = 5/131 (3%) Frame = +1 Query: 124 NDVVTAIATPIDNSPFIVSSSRDKSLLVWDL---TNPIQATQDTSSE-YGVPFRRLTGHG 291 ND + + +N +V+ S D SL +WD T P+Q ++ + E Y V + + G Sbjct: 62 NDGLFDVTWSENNEHVLVTCSGDGSLQLWDTAKATGPLQVYKEHTQEVYSVDWSQTRGE- 120 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSID-NRQIVS 468 Q +SGSWD +++WD + G + F GHE + S +S S Sbjct: 121 ------------QLVVSGSWDQTVKVWDPTVGNSLCTFRGHESVIYSTIWSPHIPGCFAS 168 Query: 469 ASRDRTIKLWN 501 AS D+T+++W+ Sbjct: 169 ASGDQTLRIWD 179
>SPG16_MOUSE (Q8K450) Sperm-associated antigen 16 protein (PF20 protein homolog)| Length = 639 Score = 54.3 bits (129), Expect = 2e-07 Identities = 37/142 (26%), Positives = 63/142 (44%), Gaps = 1/142 (0%) Frame = +1 Query: 118 GHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHF 297 GH D ++ S + +SS D ++ +WDL G L GH H Sbjct: 400 GHTDWLSGCCFHPSGSK-LATSSGDSTIKLWDLNK------------GECTLTLEGHNHA 446 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASR 477 V S G F S S D ++WD+++ GH V S+ F + +++AS Sbjct: 447 VWSCTWHSCGDFVASASLDMTSKIWDVNSERCRYTLYGHTDSVNSIEFFPFSNILLTASA 506 Query: 478 DRTIKLWNT-LGECKYTIGGDL 540 D+T+ +W+ G+C+ ++ G + Sbjct: 507 DKTLSVWDARTGKCEQSLYGHM 528 Score = 49.7 bits (117), Expect = 6e-06 Identities = 30/89 (33%), Positives = 42/89 (47%), Gaps = 3/89 (3%) Frame = +1 Query: 277 LTGHGH--FVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSID 450 LTG GH ++ G + S D ++LWDL+ G T GH V S + Sbjct: 396 LTGSGHTDWLSGCCFHPSGSKLATSSGDSTIKLWDLNKGECTLTLEGHNHAVWSCTWHSC 455 Query: 451 NRQIVSASRDRTIKLWNTLGE-CKYTIGG 534 + SAS D T K+W+ E C+YT+ G Sbjct: 456 GDFVASASLDMTSKIWDVNSERCRYTLYG 484 Score = 44.7 bits (104), Expect = 2e-04 Identities = 41/158 (25%), Positives = 58/158 (36%), Gaps = 31/158 (19%) Frame = +1 Query: 118 GHNDVVTAIAT-PIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGH 294 GH D V +I P N ++++S DK+L VWD + V T GH Sbjct: 484 GHTDSVNSIEFFPFSN--ILLTASADKTLSVWDARTGKCEQSLYGHMHSVNDATFTPRGH 541 Query: 295 FV------------------------------QDVVLSSDGQFALSGSWDGELRLWDLST 384 + +V G+ S +G + L DL + Sbjct: 542 IIASCDARGVTKLWDFRKLIPIVSIDVGPSSGNEVNFDQSGRVLAQASANGIIHLLDLKS 601 Query: 385 GVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLW 498 G + VGHE +V SV FS + S D TI+LW Sbjct: 602 G-QIHKLVGHESEVHSVVFSHLGENLYSGGSDGTIRLW 638 Score = 40.0 bits (92), Expect = 0.004 Identities = 33/130 (25%), Positives = 47/130 (36%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 + GHN V + T F+ S+S D + +WD+ + Y L GH Sbjct: 440 LEGHNHAVWS-CTWHSCGDFVASASLDMTSKIWDVNSE-------RCRY-----TLYGHT 486 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSA 471 V + L+ S D L +WD TG + GH V F+ I S Sbjct: 487 DSVNSIEFFPFSNILLTASADKTLSVWDARTGKCEQSLYGHMHSVNDATFTPRGHIIASC 546 Query: 472 SRDRTIKLWN 501 KLW+ Sbjct: 547 DARGVTKLWD 556 Score = 30.8 bits (68), Expect = 2.7 Identities = 22/80 (27%), Positives = 35/80 (43%), Gaps = 1/80 (1%) Frame = +1 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASR 477 V +V+ + +S S D ++ L G GH + F ++ ++S Sbjct: 363 VSCIVMHPCRDYLISCSEDRLWKMVGLPQGNVLLTGSGHTDWLSGCCFHPSGSKLATSSG 422 Query: 478 DRTIKLWN-TLGECKYTIGG 534 D TIKLW+ GEC T+ G Sbjct: 423 DSTIKLWDLNKGECTLTLEG 442
>GBB3_RAT (P52287) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 3 (Transducin beta chain 3) Length = 340 Score = 54.3 bits (129), Expect = 2e-07 Identities = 51/176 (28%), Positives = 71/176 (40%), Gaps = 35/176 (19%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDL--TNPIQATQDTSS----------- 252 +RGH + A+ D S +VS+S+D L+VWD TN + A SS Sbjct: 51 LRGHLAKIYAMHWATD-SKLLVSASQDGKLIVWDTYTTNKVHAIPLRSSWVMTCAYAPSG 109 Query: 253 --------------------EYGVPF-RRLTGHGHFVQDVVLSSDGQFALSGSWDGELRL 369 E V R L+ H ++ D S S D L Sbjct: 110 NFVACGGLDNMCSIYSLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTS-SGDTTCAL 168 Query: 370 WDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNTL-GECKYTIGG 534 WD+ TG FVGH D +S+A S D + +S + D + KLW+ G C+ T G Sbjct: 169 WDIETGQQKTVFVGHTGDCMSLAVSPDYKLFISGACDASAKLWDVREGTCRQTFTG 224 Score = 53.9 bits (128), Expect = 3e-07 Identities = 31/118 (26%), Positives = 54/118 (45%) Frame = +1 Query: 172 IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSW 351 IV+SS D + +WD+ Q T GH + +S D + +SG+ Sbjct: 157 IVTSSGDTTCALWDIETGQQKTV------------FVGHTGDCMSLAVSPDYKLFISGAC 204 Query: 352 DGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNTLGECKYT 525 D +LWD+ G + F GHE D+ ++ F + I + S D + +L++ + + T Sbjct: 205 DASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELT 262 Score = 34.7 bits (78), Expect = 0.18 Identities = 32/133 (24%), Positives = 50/133 (37%), Gaps = 5/133 (3%) Frame = +1 Query: 118 GHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHF 297 GH + AI N I + S D S ++DL +A Q+ LT + H Sbjct: 224 GHESDINAICF-FPNGEAICTGSDDASCRLFDL----RADQE-----------LTAYSHE 267 Query: 298 -----VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQI 462 + V S G+ +G D +WD GH+ V + + D + Sbjct: 268 SIICGITSVAFSLSGRLLFAGYDDFNCNVWDSLKCERVGVLSGHDNRVSCLGVTADGMAV 327 Query: 463 VSASRDRTIKLWN 501 + S D +K+WN Sbjct: 328 ATGSWDSFLKIWN 340
>GBB3_MOUSE (Q61011) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 3 (Transducin beta chain 3) Length = 340 Score = 54.3 bits (129), Expect = 2e-07 Identities = 51/176 (28%), Positives = 71/176 (40%), Gaps = 35/176 (19%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDL--TNPIQATQDTSS----------- 252 +RGH + A+ D S +VS+S+D L+VWD TN + A SS Sbjct: 51 LRGHLAKIYAMHWATD-SKLLVSASQDGKLIVWDTYTTNKVHAIPLRSSWVMTCAYAPSG 109 Query: 253 --------------------EYGVPF-RRLTGHGHFVQDVVLSSDGQFALSGSWDGELRL 369 E V R L+ H ++ D S S D L Sbjct: 110 NFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTS-SGDTTCAL 168 Query: 370 WDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNTL-GECKYTIGG 534 WD+ TG FVGH D +S+A S D + +S + D + KLW+ G C+ T G Sbjct: 169 WDIETGQQKTVFVGHTGDCMSLAVSPDYKLFISGACDASAKLWDVREGTCRQTFTG 224 Score = 53.9 bits (128), Expect = 3e-07 Identities = 31/118 (26%), Positives = 54/118 (45%) Frame = +1 Query: 172 IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSW 351 IV+SS D + +WD+ Q T GH + +S D + +SG+ Sbjct: 157 IVTSSGDTTCALWDIETGQQKTV------------FVGHTGDCMSLAVSPDYKLFISGAC 204 Query: 352 DGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNTLGECKYT 525 D +LWD+ G + F GHE D+ ++ F + I + S D + +L++ + + T Sbjct: 205 DASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELT 262 Score = 33.1 bits (74), Expect = 0.54 Identities = 29/128 (22%), Positives = 47/128 (36%) Frame = +1 Query: 118 GHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHF 297 GH + AI N I + S D S ++DL + T + + G Sbjct: 224 GHESDINAICF-FPNGEAICTGSDDASCRLFDLRADQELTAYSQESI------ICG---- 272 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASR 477 + V S G+ +G D +WD GH+ V + + D + + S Sbjct: 273 ITSVAFSLSGRLLFAGYDDFNCNVWDSLKCERVGILSGHDNRVSCLGVTADGMAVATGSW 332 Query: 478 DRTIKLWN 501 D +K+WN Sbjct: 333 DSFLKIWN 340
>MORG1_XENLA (Q3KQ62) Mitogen-activated protein kinase organizer 1 (MAPK| organizer 1) Length = 314 Score = 53.9 bits (128), Expect = 3e-07 Identities = 38/123 (30%), Positives = 59/123 (47%) Frame = +1 Query: 133 VTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVV 312 V A+ +D + + ++ DKSL +W NP + G + +GHG+ V D Sbjct: 28 VRAVRFNVDGN-YCMTCGSDKSLKLW---NPHK---------GSLLKTYSGHGYEVLDTA 74 Query: 313 LSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIK 492 S D S S D + LWD++ G R+F GH V V F+ + I+S S D +I+ Sbjct: 75 GSCDNSQLCSCSSDKTVILWDVAQGQVVRKFRGHAGKVNCVQFNEEATVIISGSIDSSIR 134 Query: 493 LWN 501 W+ Sbjct: 135 CWD 137 Score = 38.5 bits (88), Expect = 0.013 Identities = 34/131 (25%), Positives = 59/131 (45%), Gaps = 4/131 (3%) Frame = +1 Query: 115 RGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTN----PIQATQDTSSEYGVPFRRLT 282 RGH V + + + I+S S D S+ WD + IQ + G+ +++ Sbjct: 106 RGHAGKVNCVQFN-EEATVIISGSIDSSIRCWDCRSRRPDAIQIMDEAKD--GISSVKVS 162 Query: 283 GHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQI 462 H L+GS DG LR +DL G ++G + V+FS D++ + Sbjct: 163 AHE--------------ILAGSVDGNLRRYDLRKGEMCADYLG--SPITCVSFSQDSQCL 206 Query: 463 VSASRDRTIKL 495 +++S D T++L Sbjct: 207 LASSLDSTLRL 217 Score = 36.2 bits (82), Expect = 0.063 Identities = 22/67 (32%), Positives = 30/67 (44%), Gaps = 2/67 (2%) Frame = +1 Query: 307 VVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHE--KDVLSVAFSIDNRQIVSASRD 480 V S D Q L+ S D LRL D TG + GH+ L S + ++S S D Sbjct: 197 VSFSQDSQCLLASSLDSTLRLLDKDTGELLGEYTGHQNLSYKLDSCLSEKDTHVLSCSED 256 Query: 481 RTIKLWN 501 T+ W+ Sbjct: 257 GTVCFWD 263
>APAF_HUMAN (O14727) Apoptotic protease-activating factor 1 (Apaf-1)| Length = 1248 Score = 53.9 bits (128), Expect = 3e-07 Identities = 41/131 (31%), Positives = 58/131 (44%), Gaps = 1/131 (0%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWD-LTNPIQATQDTSSEYGVPFRRLTGH 288 ++ H D V A D+ FI + S DK + +W+ +T + T D SE Sbjct: 653 IKAHEDEVLCCAFSTDDR-FIATCSVDKKVKIWNSMTGELVHTYDEHSEQ-------VNC 704 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVS 468 HF SS +GS D L+LWDL+ GH V FS D++ + S Sbjct: 705 CHFTN----SSHHLLLATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLAS 760 Query: 469 ASRDRTIKLWN 501 S D T+KLW+ Sbjct: 761 CSADGTLKLWD 771 Score = 50.8 bits (120), Expect = 2e-06 Identities = 28/75 (37%), Positives = 43/75 (57%) Frame = +1 Query: 277 LTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNR 456 L GH V+D L + + LS S+DG +++W++ TG + FV H+ VLS S D Sbjct: 1040 LRGHQETVKDFRLLKNSRL-LSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDAT 1098 Query: 457 QIVSASRDRTIKLWN 501 + S S D+T K+W+ Sbjct: 1099 KFSSTSADKTAKIWS 1113 Score = 49.7 bits (117), Expect = 6e-06 Identities = 29/81 (35%), Positives = 41/81 (50%), Gaps = 1/81 (1%) Frame = +1 Query: 286 HGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIV 465 H V S DGQ S D L+++ TG HE +VL AFS D+R I Sbjct: 614 HTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIA 673 Query: 466 SASRDRTIKLWNTL-GECKYT 525 + S D+ +K+WN++ GE +T Sbjct: 674 TCSVDKKVKIWNSMTGELVHT 694 Score = 42.4 bits (98), Expect = 9e-04 Identities = 34/125 (27%), Positives = 53/125 (42%), Gaps = 9/125 (7%) Frame = +1 Query: 178 SSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSWDG 357 S+S DK+ +W S + +P L GH V+ S D +G +G Sbjct: 1102 STSADKTAKIW------------SFDLLLPLHELRGHNGCVRCSAFSVDSTLLATGDDNG 1149 Query: 358 ELRLWDLSTG--------VTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNTL-G 510 E+R+W++S G ++ H V + FS D + ++SA IK WN + G Sbjct: 1150 EIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLCFSPDGKMLISAG--GYIKWWNVVTG 1207 Query: 511 ECKYT 525 E T Sbjct: 1208 ESSQT 1212 Score = 38.1 bits (87), Expect = 0.017 Identities = 24/80 (30%), Positives = 34/80 (42%) Frame = +1 Query: 280 TGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQ 459 TGH +Q S A+ + LW+ + GH V V FS D Sbjct: 837 TGHHSTIQYCDFSPQNHLAVVALSQYCVELWNTDSRSKVADCRGHLSWVHGVMFSPDGSS 896 Query: 460 IVSASRDRTIKLWNTLGECK 519 +++S D+TI+LW T CK Sbjct: 897 FLTSSDDQTIRLWETKKVCK 916 Score = 36.2 bits (82), Expect = 0.063 Identities = 39/165 (23%), Positives = 68/165 (41%), Gaps = 26/165 (15%) Frame = +1 Query: 115 RGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQ-ATQDTSSEYGVPF------- 270 RGH V + D S F+ SS D+++ +W+ + + E V F Sbjct: 879 RGHLSWVHGVMFSPDGSSFLTSSD-DQTIRLWETKKVCKNSAVMLKQEVDVVFQENEVMV 937 Query: 271 ------RRL------TGHGHFVQDV-----VLSSDGQFALSGSWDGELRLWDLSTGVTTR 399 RRL TG ++ + LS Q+ G +G + + +L + Sbjct: 938 LAVDHIRRLQLINGRTGQIDYLTEAQVSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQ 997 Query: 400 RFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN-TLGECKYTIG 531 H+K V + F+ D + ++S+S D I++WN L +C + G Sbjct: 998 SRFQHKKTVWHIQFTADEKTLISSSDDAEIQVWNWQLDKCIFLRG 1042 Score = 32.3 bits (72), Expect = 0.92 Identities = 21/76 (27%), Positives = 40/76 (52%), Gaps = 2/76 (2%) Frame = +1 Query: 286 HGHFVQDVVLSSDGQFALSGSWDGELRLWD--LSTGVTTRRFVGHEKDVLSVAFSIDNRQ 459 H V + ++D + +S S D E+++W+ L + R GH++ V + N + Sbjct: 1002 HKKTVWHIQFTADEKTLISSSDDAEIQVWNWQLDKCIFLR---GHQETVKDFRL-LKNSR 1057 Query: 460 IVSASRDRTIKLWNTL 507 ++S S D T+K+WN + Sbjct: 1058 LLSWSFDGTVKVWNII 1073 Score = 30.4 bits (67), Expect = 3.5 Identities = 33/136 (24%), Positives = 56/136 (41%), Gaps = 5/136 (3%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 M GH + V D+ + S S D +L +WD T+ + ++ F L Sbjct: 739 MFGHTNSVNHCRFSPDDK-LLASCSADGTLKLWDATSANERKSINVKQF---FLNLEDPQ 794 Query: 292 HFVQDVVL----SSDGQFALSGSWDGELRLWDLST-GVTTRRFVGHEKDVLSVAFSIDNR 456 ++ +V S+DG + + ++ L+D+ T G+ GH + FS N Sbjct: 795 EDMEVIVKCCSWSADGARIMVAA-KNKIFLFDIHTSGLLGEIHTGHHSTIQYCDFSPQNH 853 Query: 457 QIVSASRDRTIKLWNT 504 V A ++LWNT Sbjct: 854 LAVVALSQYCVELWNT 869
>YIRF_SCHPO (Q9P7I3) Hypothetical WD-repeat protein C664.15 in chromosome I| Length = 651 Score = 53.9 bits (128), Expect = 3e-07 Identities = 40/142 (28%), Positives = 70/142 (49%), Gaps = 11/142 (7%) Frame = +1 Query: 109 VMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNP--IQA-------TQDTSSEYG 261 V+ H VTA+A D+ +++ + DK++ WD+ IQ T DTS+ Sbjct: 430 VLTSHTAPVTALALSSDD--VLITGADDKTVRQWDIVTGRCIQTLDFVWAETHDTSTS-- 485 Query: 262 VPFRRLTGHGHFVQDVVLSSDGQFAL--SGSWDGELRLWDLSTGVTTRRFVGHEKDVLSV 435 + L + + + + D A SG+ DG +R+WDL G+ R F+GH + S+ Sbjct: 486 ---QILVSDTYKQEPFIRALDCLDAAVASGTVDGLIRIWDLRIGLPVRSFIGHTAPISSL 542 Query: 436 AFSIDNRQIVSASRDRTIKLWN 501 F D+ + S S D ++++W+ Sbjct: 543 QF--DSNHLYSGSYDNSVRIWD 562 Score = 46.2 bits (108), Expect = 6e-05 Identities = 36/119 (30%), Positives = 60/119 (50%), Gaps = 11/119 (9%) Frame = +1 Query: 94 LVYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDL-------TNPIQATQDTSS 252 +VY G ++GH+D V+ +A FI + S D ++ +W+L NP++ + ++ Sbjct: 364 VVYLGSLKGHSDYVSCLAI---QDSFIATGSMDTTVRLWNLDNDVLHKDNPVEESLNSPP 420 Query: 253 EYGV--PFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTG--VTTRRFVGHE 417 + V LT H V + LSSD ++G+ D +R WD+ TG + T FV E Sbjct: 421 DQPVDNATNVLTSHTAPVTALALSSD-DVLITGADDKTVRQWDIVTGRCIQTLDFVWAE 478 Score = 40.8 bits (94), Expect = 0.003 Identities = 36/162 (22%), Positives = 68/162 (41%), Gaps = 24/162 (14%) Frame = +1 Query: 115 RGHNDVVTAIATPIDNSPF--IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 + H++ +T++ + PF + ++S DK++ VWD+ + L GH Sbjct: 329 QAHSEYITSLDF---SHPFGTLATASTDKTVKVWDMAGVVYLGS------------LKGH 373 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGV---------------------TTRRF 405 +V L+ F +GS D +RLW+L V T Sbjct: 374 SDYVS--CLAIQDSFIATGSMDTTVRLWNLDNDVLHKDNPVEESLNSPPDQPVDNATNVL 431 Query: 406 VGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNTL-GECKYTI 528 H V ++A S D+ +++ + D+T++ W+ + G C T+ Sbjct: 432 TSHTAPVTALALSSDD-VLITGADDKTVRQWDIVTGRCIQTL 472 Score = 37.4 bits (85), Expect = 0.028 Identities = 28/112 (25%), Positives = 51/112 (45%) Frame = +1 Query: 172 IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSW 351 + S + D + +WDL G+P R GH + L D SGS+ Sbjct: 509 VASGTVDGLIRIWDL------------RIGLPVRSFIGHTAPISS--LQFDSNHLYSGSY 554 Query: 352 DGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNTL 507 D +R+WDL +G + + EK V S+ + ++ AS + +++++T+ Sbjct: 555 DNSVRIWDLRSG-SPINIIPMEKKVNSL--RLYQGRLAVASDEPNVRIFDTV 603 Score = 33.5 bits (75), Expect = 0.41 Identities = 19/77 (24%), Positives = 35/77 (45%) Frame = +1 Query: 271 RRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSID 450 ++ H ++ + S + S D +++WD++ V GH V +A I Sbjct: 326 KQFQAHSEYITSLDFSHPFGTLATASTDKTVKVWDMAGVVYLGSLKGHSDYVSCLA--IQ 383 Query: 451 NRQIVSASRDRTIKLWN 501 + I + S D T++LWN Sbjct: 384 DSFIATGSMDTTVRLWN 400 Score = 30.8 bits (68), Expect = 2.7 Identities = 13/42 (30%), Positives = 24/42 (57%) Frame = +1 Query: 385 GVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNTLG 510 G ++F H + + S+ FS + +AS D+T+K+W+ G Sbjct: 322 GNLVKQFQAHSEYITSLDFSHPFGTLATASTDKTVKVWDMAG 363
>TBLX_MOUSE (Q9QXE7) F-box-like/WD-repeat protein TBL1X (Transducin beta-like| 1X protein) Length = 527 Score = 53.9 bits (128), Expect = 3e-07 Identities = 39/139 (28%), Positives = 58/139 (41%), Gaps = 9/139 (6%) Frame = +1 Query: 115 RGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGH 294 +GH + V AI + + S S D +L +W + QD L H Sbjct: 359 QGHTNEVNAIKWD-PSGMLLASCSDDMTLKIWSMK------QDAC------VHDLQAHSK 405 Query: 295 FVQDVVLSSDGQ---------FALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSI 447 + + S G S S+D +RLWD+ GV H++ V SVAFS Sbjct: 406 EIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDVERGVCIHTLTKHQEPVYSVAFSP 465 Query: 448 DNRQIVSASRDRTIKLWNT 504 D + + S S D+ + +WNT Sbjct: 466 DGKYLASGSFDKCVHIWNT 484 Score = 41.2 bits (95), Expect = 0.002 Identities = 41/147 (27%), Positives = 64/147 (43%), Gaps = 8/147 (5%) Frame = +1 Query: 103 AGVMRGHNDVVTAIA-TPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRL 279 A V+RGH V A P+ S + S S D + +W+L + S V + Sbjct: 175 ATVLRGHESEVFICAWNPV--SDLLASGSGDSTARIWNLNE----NSNGGSTQLVLRHCI 228 Query: 280 TGHGHFV---QDVVL---SSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAF 441 GH V +DV +SDG +GS+DG R+W G H+ + ++ + Sbjct: 229 REGGHDVPSNKDVTSLDWNSDGTLLATGSYDGFARIW-TEDGNLASTLGQHKGPIFALKW 287 Query: 442 SIDNRQIVSASRDRTIKLWNT-LGECK 519 + I+SA D+T +W+ GE K Sbjct: 288 NKKGNYILSAGVDKTTIIWDAHTGEAK 314 Score = 40.0 bits (92), Expect = 0.004 Identities = 28/93 (30%), Positives = 43/93 (46%), Gaps = 1/93 (1%) Frame = +1 Query: 136 TAIATPIDNSPFIVSS-SRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVV 312 T AT NS +++S S D ++ +WD+ E GV LT H V V Sbjct: 415 TGPATSNPNSNIMLASASFDSTVRLWDV------------ERGVCIHTLTKHQEPVYSVA 462 Query: 313 LSSDGQFALSGSWDGELRLWDLSTGVTTRRFVG 411 S DG++ SGS+D + +W+ +G + G Sbjct: 463 FSPDGKYLASGSFDKCVHIWNTQSGSLVHSYRG 495 Score = 38.9 bits (89), Expect = 0.010 Identities = 24/98 (24%), Positives = 41/98 (41%), Gaps = 10/98 (10%) Frame = +1 Query: 265 PFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFS 444 P + GH + V + G S S D L++W + H K++ ++ +S Sbjct: 354 PVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDACVHDLQAHSKEIYTIKWS 413 Query: 445 ---------IDNRQIVSASRDRTIKLWNT-LGECKYTI 528 N + SAS D T++LW+ G C +T+ Sbjct: 414 PTGPATSNPNSNIMLASASFDSTVRLWDVERGVCIHTL 451 Score = 33.1 bits (74), Expect = 0.54 Identities = 28/103 (27%), Positives = 42/103 (40%), Gaps = 14/103 (13%) Frame = +1 Query: 277 LTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDL-------STGVTTRRFV---GHE--- 417 L GH V + SGS D R+W+L ST + R + GH+ Sbjct: 178 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPS 237 Query: 418 -KDVLSVAFSIDNRQIVSASRDRTIKLWNTLGECKYTIGGDLG 543 KDV S+ ++ D + + S D ++W G T+G G Sbjct: 238 NKDVTSLDWNSDGTLLATGSYDGFARIWTEDGNLASTLGQHKG 280
>YA4E_SCHPO (Q09731) Hypothetical WD-repeat protein C31A2.14 in chromosome I| Length = 962 Score = 53.5 bits (127), Expect = 4e-07 Identities = 37/128 (28%), Positives = 57/128 (44%), Gaps = 1/128 (0%) Frame = +1 Query: 121 HNDVVTAIATP-IDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHF 297 H D V ++ P SP + S DK ++VWD Q+ +P L G Sbjct: 122 HTDYVKRVSIPKYSKSPLVASGGLDKRIIVWDYN----VGQEVMRFEQLPDCSLVV-GPR 176 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASR 477 L+++ +G +++LWD + VGH +V + S D R I++AS Sbjct: 177 SGVYSLAANNNIIANGGLQKDIQLWDCVSKKRITDLVGHTDNVRDILISDDGRTILTASS 236 Query: 478 DRTIKLWN 501 D TIKLW+ Sbjct: 237 DATIKLWS 244 Score = 41.2 bits (95), Expect = 0.002 Identities = 23/89 (25%), Positives = 38/89 (42%) Frame = +1 Query: 160 NSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFAL 339 N+ I + K + +WD + + T L GH V+D+++S DG+ L Sbjct: 185 NNNIIANGGLQKDIQLWDCVSKKRITD------------LVGHTDNVRDILISDDGRTIL 232 Query: 340 SGSWDGELRLWDLSTGVTTRRFVGHEKDV 426 + S D ++LW L F+ H V Sbjct: 233 TASSDATIKLWSLRAQKCLFSFIAHSDSV 261 Score = 34.7 bits (78), Expect = 0.18 Identities = 22/72 (30%), Positives = 31/72 (43%), Gaps = 8/72 (11%) Frame = +1 Query: 340 SGSWDGELRLWDLS-----TGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN- 501 SG DG+L WD+ + H V +A + D+ ++S S D T+KLW Sbjct: 49 SGGRDGQLFGWDIGYDYGKASQPLAKIQAHSAWVNDIALTHDSEGVISCSSDSTVKLWKP 108 Query: 502 --TLGECKYTIG 531 C TIG Sbjct: 109 HVLNASCLSTIG 120
>FBXW7_HUMAN (Q969H0) F-box/WD-repeat protein 7 (F-box and WD-40 domain protein| 7) (F-box protein FBX30) (hCdc4) (Archipelago homolog) (hAgo) (SEL-10) Length = 707 Score = 53.5 bits (127), Expect = 4e-07 Identities = 39/122 (31%), Positives = 60/122 (49%), Gaps = 1/122 (0%) Frame = +1 Query: 172 IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSW 351 I+S S D++L VW+ +E G L GH V+ + L + +SGS Sbjct: 434 IISGSTDRTLKVWN------------AETGECIHTLYGHTSTVRCMHLHE--KRVVSGSR 479 Query: 352 DGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNTLGE-CKYTI 528 D LR+WD+ TG +GH V V + D R++VS + D +K+W+ E C +T+ Sbjct: 480 DATLRVWDIETGQCLHVLMGHVAAVRCVQY--DGRRVVSGAYDFMVKVWDPETETCLHTL 537 Query: 529 GG 534 G Sbjct: 538 QG 539 Score = 53.1 bits (126), Expect = 5e-07 Identities = 41/143 (28%), Positives = 63/143 (44%), Gaps = 1/143 (0%) Frame = +1 Query: 109 VMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 V+ GH V A+ + +VS + D + VWD E L GH Sbjct: 496 VLMGH---VAAVRCVQYDGRRVVSGAYDFMVKVWD------------PETETCLHTLQGH 540 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVS 468 + V L DG +SGS D +R+WD+ TG GH+ L+ + + +VS Sbjct: 541 TNRVYS--LQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQS--LTSGMELKDNILVS 596 Query: 469 ASRDRTIKLWN-TLGECKYTIGG 534 + D T+K+W+ G+C T+ G Sbjct: 597 GNADSTVKIWDIKTGQCLQTLQG 619 Score = 50.1 bits (118), Expect = 4e-06 Identities = 34/87 (39%), Positives = 44/87 (50%), Gaps = 1/87 (1%) Frame = +1 Query: 277 LTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNR 456 L GH V L G +SGS D L++W TG R VGH V S + + Sbjct: 376 LKGHDDHVI-TCLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWS--SQMRDN 432 Query: 457 QIVSASRDRTIKLWNT-LGECKYTIGG 534 I+S S DRT+K+WN GEC +T+ G Sbjct: 433 IIISGSTDRTLKVWNAETGECIHTLYG 459 Score = 48.1 bits (113), Expect = 2e-05 Identities = 32/111 (28%), Positives = 52/111 (46%), Gaps = 1/111 (0%) Frame = +1 Query: 172 IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSW 351 +VS S D S+ VWD+ E G LTGH + L + +SG+ Sbjct: 554 VVSGSLDTSIRVWDV------------ETGNCIHTLTGHQSLTSGMELKDN--ILVSGNA 599 Query: 352 DGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQ-IVSASRDRTIKLWN 501 D +++WD+ TG + G K +V N+ ++++S D T+KLW+ Sbjct: 600 DSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLWD 650
>PEX7_HUMAN (O00628) Peroxisomal targeting signal 2 receptor (PTS2 receptor)| (Peroxin-7) Length = 323 Score = 53.5 bits (127), Expect = 4e-07 Identities = 37/131 (28%), Positives = 62/131 (47%), Gaps = 5/131 (3%) Frame = +1 Query: 124 NDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTN---PIQATQDTSSE-YGVPFRRLTGHG 291 ND + + +N +++ S D SL +WD P+Q ++ + E Y V + + G Sbjct: 67 NDGLFDVTWSENNEHVLITCSGDGSLQLWDTAKAAGPLQVYKEHAQEVYSVDWSQTRGE- 125 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSID-NRQIVS 468 Q +SGSWD ++LWD + G + F GHE + S +S S Sbjct: 126 ------------QLVVSGSWDQTVKLWDPTVGKSLCTFRGHESIIYSTIWSPHIPGCFAS 173 Query: 469 ASRDRTIKLWN 501 AS D+T+++W+ Sbjct: 174 ASGDQTLRIWD 184
>PRP46_CANGA (Q6FJZ9) Pre-mRNA-splicing factor PRP46 (Pre-mRNA-processing| protein 46) Length = 427 Score = 53.5 bits (127), Expect = 4e-07 Identities = 34/131 (25%), Positives = 59/131 (45%) Frame = +1 Query: 109 VMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 V+ GH+ V IA ++ + + S DK++ +W+L + G L H Sbjct: 110 VIHGHHGWVRCIAMDKVDNEWFATGSNDKTIKIWNLAS------------GKLKVTLKAH 157 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVS 468 V+D+ +S+ + S S D ++ WDL R + GH V +V +V+ Sbjct: 158 DMTVRDLAISNRHPYMFSVSEDKTVKCWDLEKNTAIRNYHGHLSGVHTVDIHPTVDVVVT 217 Query: 469 ASRDRTIKLWN 501 A RD +K+W+ Sbjct: 218 AGRDSVVKVWD 228 Score = 47.4 bits (111), Expect = 3e-05 Identities = 31/130 (23%), Positives = 57/130 (43%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 ++ H+ V +A + P++ S S DK++ WDL E R GH Sbjct: 154 LKAHDMTVRDLAIS-NRHPYMFSVSEDKTVKCWDL------------EKNTAIRNYHGHL 200 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSA 471 V V + ++ D +++WD+ T + GH+ + V + Q++S+ Sbjct: 201 SGVHTVDIHPTVDVVVTAGRDSVVKVWDIRTRLPVMTLPGHKGPITKVRCLPVDPQVISS 260 Query: 472 SRDRTIKLWN 501 S D +I+LW+ Sbjct: 261 SVDASIRLWD 270 Score = 43.9 bits (102), Expect = 3e-04 Identities = 33/122 (27%), Positives = 56/122 (45%), Gaps = 1/122 (0%) Frame = +1 Query: 118 GHNDVVTAI-ATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGH 294 GH +T + P+D P ++SSS D S+ +WDL G + LT H Sbjct: 240 GHKGPITKVRCLPVD--PQVISSSVDASIRLWDLV------------AGKSMKVLTHHQR 285 Query: 295 FVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSAS 474 V+D+ + +F+ + + ++R W L G FV + DV++ SI+ ++ A Sbjct: 286 TVRDISV-HPSEFSFASACTNDIRSWLLPKGELLTNFVSQDLDVINTV-SINQDDVLFAG 343 Query: 475 RD 480 D Sbjct: 344 SD 345 Score = 41.6 bits (96), Expect = 0.002 Identities = 21/78 (26%), Positives = 42/78 (53%), Gaps = 1/78 (1%) Frame = +1 Query: 271 RRLTGHGHFVQDVVLSS-DGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSI 447 R + GH +V+ + + D ++ +GS D +++W+L++G H+ V +A S Sbjct: 109 RVIHGHHGWVRCIAMDKVDNEWFATGSNDKTIKIWNLASGKLKVTLKAHDMTVRDLAISN 168 Query: 448 DNRQIVSASRDRTIKLWN 501 + + S S D+T+K W+ Sbjct: 169 RHPYMFSVSEDKTVKCWD 186 Score = 36.6 bits (83), Expect = 0.049 Identities = 29/110 (26%), Positives = 46/110 (41%), Gaps = 1/110 (0%) Frame = +1 Query: 172 IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH-GHFVQDVVLSSDGQFALSGS 348 +V++ RD + VWD+ + P L GH G + L D Q +S S Sbjct: 215 VVTAGRDSVVKVWDIRTRL------------PVMTLPGHKGPITKVRCLPVDPQ-VISSS 261 Query: 349 WDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLW 498 D +RLWDL G + + H++ V ++ SA + I+ W Sbjct: 262 VDASIRLWDLVAGKSMKVLTHHQRTVRDISVHPSEFSFASACTN-DIRSW 310
>PRP46_YARLI (Q6C709) Pre-mRNA-splicing factor PRP46 (Pre-mRNA-processing| protein 46) Length = 472 Score = 53.5 bits (127), Expect = 4e-07 Identities = 38/132 (28%), Positives = 60/132 (45%), Gaps = 1/132 (0%) Frame = +1 Query: 109 VMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDL-TNPIQATQDTSSEYGVPFRRLTG 285 V+ GH V ++ +N F S+ DK++ +WDL T ++ T LTG Sbjct: 158 VITGHQGWVRSVCVEPENQWFATGSA-DKTIKIWDLATGKLRLT-------------LTG 203 Query: 286 HGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIV 465 H V+ + +S + SG D ++ WDL T R + GH V S+ +V Sbjct: 204 HIMGVRALGVSPRHPYMFSGGEDKMVKCWDLETNKVVRHYHGHLSAVYSLDIHPTLDVLV 263 Query: 466 SASRDRTIKLWN 501 SA RD ++W+ Sbjct: 264 SAGRDAVARVWD 275 Score = 50.1 bits (118), Expect = 4e-06 Identities = 23/78 (29%), Positives = 42/78 (53%) Frame = +1 Query: 268 FRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSI 447 +R +TGH +V+ V + + Q+ +GS D +++WDL+TG GH V ++ S Sbjct: 156 YRVITGHQGWVRSVCVEPENQWFATGSADKTIKIWDLATGKLRLTLTGHIMGVRALGVSP 215 Query: 448 DNRQIVSASRDRTIKLWN 501 + + S D+ +K W+ Sbjct: 216 RHPYMFSGGEDKMVKCWD 233 Score = 49.7 bits (117), Expect = 6e-06 Identities = 31/113 (27%), Positives = 47/113 (41%), Gaps = 1/113 (0%) Frame = +1 Query: 166 PFIVSSSRDKSLLVWDL-TNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALS 342 P++ S DK + WDL TN + R GH V + + +S Sbjct: 218 PYMFSGGEDKMVKCWDLETNKV-------------VRHYHGHLSAVYSLDIHPTLDVLVS 264 Query: 343 GSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN 501 D R+WD+ T GH+ + V F Q+++AS D T++LWN Sbjct: 265 AGRDAVARVWDIRTRDPVVVLSGHKSTINRVKFQASEPQVITASADETVRLWN 317 Score = 37.4 bits (85), Expect = 0.028 Identities = 29/109 (26%), Positives = 46/109 (42%) Frame = +1 Query: 172 IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSW 351 +VS+ RD VWD+ T+D P L+GH + V + ++ S Sbjct: 262 LVSAGRDAVARVWDIR-----TRD-------PVVVLSGHKSTINRVKFQASEPQVITASA 309 Query: 352 DGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLW 498 D +RLW+L G T H+K V + + +AS + + K W Sbjct: 310 DETVRLWNLQAGKTMTTLTHHKKSVRGLTLHPEEFTFSTASANSS-KQW 357
>UTP15_PONPY (Q5REE0) U3 small nucleolar RNA-associated protein 15 homolog| Length = 518 Score = 53.5 bits (127), Expect = 4e-07 Identities = 25/60 (41%), Positives = 39/60 (65%) Frame = +1 Query: 322 DGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN 501 DG+ ++GS DG ++L+D+S R+F GH K V +V F+ D +VS + D T+KLW+ Sbjct: 91 DGRLIVAGSEDGGVQLFDISGRAPLRQFEGHTKAVHTVDFTADKYHVVSGADDYTVKLWD 150 Score = 37.4 bits (85), Expect = 0.028 Identities = 28/120 (23%), Positives = 51/120 (42%), Gaps = 1/120 (0%) Frame = +1 Query: 145 ATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSD 324 AT + IV+ S D + ++D++ P R+ GH V V ++D Sbjct: 86 ATFRQDGRLIVAGSEDGGVQLFDISGR------------APLRQFEGHTKAVHTVDFTAD 133 Query: 325 GQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDV-LSVAFSIDNRQIVSASRDRTIKLWN 501 +SG+ D ++LWD+ F H V A ++ ++ S D T+K+++ Sbjct: 134 KYHVVSGADDYTVKLWDIPNSKEVLTFKEHSDYVRCGCASKLNPDLFITGSYDHTVKMFD 193 Score = 30.0 bits (66), Expect = 4.5 Identities = 21/81 (25%), Positives = 39/81 (48%) Frame = +1 Query: 277 LTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNR 456 L H V + LSS GQ LSGS D +++++ ++ F + +LS+A + ++ Sbjct: 244 LKNHHKTVTCLCLSSSGQRLLSGSLDRKVKVYSTTSYKVVHSF-DYAASILSLALAHEDE 302 Query: 457 QIVSASRDRTIKLWNTLGECK 519 IV + + + + E K Sbjct: 303 TIVVGMTNGILSVKHRKSEAK 323
>FBXW7_MOUSE (Q8VBV4) F-box/WD-repeat protein 7 (F-box and WD-40 domain protein| 7) (F-box protein FBW7) (F-box protein Fbxw6) (F-box-WD40 repeat protein 6) (SEL-10) Length = 629 Score = 53.5 bits (127), Expect = 4e-07 Identities = 39/122 (31%), Positives = 60/122 (49%), Gaps = 1/122 (0%) Frame = +1 Query: 172 IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSW 351 I+S S D++L VW+ +E G L GH V+ + L + +SGS Sbjct: 356 IISGSTDRTLKVWN------------AETGECIHTLYGHTSTVRCMHLHE--KRVVSGSR 401 Query: 352 DGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNTLGE-CKYTI 528 D LR+WD+ TG +GH V V + D R++VS + D +K+W+ E C +T+ Sbjct: 402 DATLRVWDIETGQCLHVLMGHVAAVRCVQY--DGRRVVSGAYDFMVKVWDPETETCLHTL 459 Query: 529 GG 534 G Sbjct: 460 QG 461 Score = 53.1 bits (126), Expect = 5e-07 Identities = 41/143 (28%), Positives = 63/143 (44%), Gaps = 1/143 (0%) Frame = +1 Query: 109 VMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 V+ GH V A+ + +VS + D + VWD E L GH Sbjct: 418 VLMGH---VAAVRCVQYDGRRVVSGAYDFMVKVWD------------PETETCLHTLQGH 462 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVS 468 + V L DG +SGS D +R+WD+ TG GH+ L+ + + +VS Sbjct: 463 TNRVYS--LQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQS--LTSGMELKDNILVS 518 Query: 469 ASRDRTIKLWN-TLGECKYTIGG 534 + D T+K+W+ G+C T+ G Sbjct: 519 GNADSTVKIWDIKTGQCLQTLQG 541 Score = 50.1 bits (118), Expect = 4e-06 Identities = 34/87 (39%), Positives = 44/87 (50%), Gaps = 1/87 (1%) Frame = +1 Query: 277 LTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNR 456 L GH V L G +SGS D L++W TG R VGH V S + + Sbjct: 298 LKGHDDHVI-TCLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWS--SQMRDN 354 Query: 457 QIVSASRDRTIKLWNT-LGECKYTIGG 534 I+S S DRT+K+WN GEC +T+ G Sbjct: 355 IIISGSTDRTLKVWNAETGECIHTLYG 381 Score = 48.1 bits (113), Expect = 2e-05 Identities = 32/111 (28%), Positives = 52/111 (46%), Gaps = 1/111 (0%) Frame = +1 Query: 172 IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSW 351 +VS S D S+ VWD+ E G LTGH + L + +SG+ Sbjct: 476 VVSGSLDTSIRVWDV------------ETGNCIHTLTGHQSLTSGMELKDN--ILVSGNA 521 Query: 352 DGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQ-IVSASRDRTIKLWN 501 D +++WD+ TG + G K +V N+ ++++S D T+KLW+ Sbjct: 522 DSTVKIWDIKTGQCLQTLQGPSKHQSAVTCLQFNKNFVITSSDDGTVKLWD 572
>PRP46_KLULA (Q6CKE8) Pre-mRNA-splicing factor PRP46 (Pre-mRNA-processing| protein 46) Length = 434 Score = 53.5 bits (127), Expect = 4e-07 Identities = 38/133 (28%), Positives = 58/133 (43%), Gaps = 2/133 (1%) Frame = +1 Query: 109 VMRGHNDVVTAIAT-PIDNSPFIVSSSRDKSLLVWDLT-NPIQATQDTSSEYGVPFRRLT 282 V+ GH V + P+DN F + S D ++ +WDL ++ T L Sbjct: 117 VINGHTGWVRCVCVDPVDNEWF-ATGSNDTTIKIWDLAAGKLKIT-------------LI 162 Query: 283 GHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQI 462 GH V+D+ +S + S S D ++ WDL R F GH V +V I Sbjct: 163 GHVMSVRDIAISKRHPYMFSASEDKLVKCWDLERNTAIRDFHGHLSGVHTVDVHPSLDII 222 Query: 463 VSASRDRTIKLWN 501 +A RD ++LW+ Sbjct: 223 ATAGRDAVVRLWD 235 Score = 45.1 bits (105), Expect = 1e-04 Identities = 30/114 (26%), Positives = 47/114 (41%) Frame = +1 Query: 166 PFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSG 345 P++ S+S DK + WDL E R GH V V + + Sbjct: 178 PYMFSASEDKLVKCWDL------------ERNTAIRDFHGHLSGVHTVDVHPSLDIIATA 225 Query: 346 SWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNTL 507 D +RLWD+ + GH+ + V + QI+S S D T++LW+ + Sbjct: 226 GRDAVVRLWDIRSRSEIMVLPGHKSPINKVKCLPVDPQIISCSGDATVRLWDII 279
>CWF17_SCHPO (O94620) Cell cycle control protein cwf17| Length = 340 Score = 53.5 bits (127), Expect = 4e-07 Identities = 46/180 (25%), Positives = 75/180 (41%), Gaps = 37/180 (20%) Frame = +1 Query: 115 RGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWD---------------LTNPIQATQDTS 249 +GH VV A+ S + S S D ++ VWD LT A Q T Sbjct: 132 KGHAGVVNALDVLKVGSELLTSVSDDCTMKVWDSRSKDCIKTIEEKYPLTAVAIAQQGTQ 191 Query: 250 SEYGV--------PFRR------LTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTG 387 G R L GH + + +S DG LS S D +R++D+ Sbjct: 192 VFIGGIDGAIKIWDLRNNHCSHVLKGHKDIITSLAISKDGSSLLSNSMDNTVRIFDVKPF 251 Query: 388 VTTRRFV--------GHEKDVLSVAFSIDNRQIVSASRDRTIKLWNTLGECKYTIGGDLG 543 + +R + G E ++L VA+S ++R + + S D+ + +W+ G+ +Y + G G Sbjct: 252 ASAQRQLQIFEGAIHGQEHNLLGVAWSRNSRFVGAGSSDKNVYVWSATGDLRYVLPGHEG 311 Score = 50.8 bits (120), Expect = 2e-06 Identities = 39/129 (30%), Positives = 63/129 (48%) Frame = +1 Query: 109 VMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 V++GH D++T++A D S ++S+S D ++ ++D+ A + G + G Sbjct: 214 VLKGHKDIITSLAISKDGSS-LLSNSMDNTVRIFDVKPFASAQRQLQIFEGA----IHGQ 268 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVS 468 H + V S + +F +GS D + +W +TG GHE V V F I+S Sbjct: 269 EHNLLGVAWSRNSRFVGAGSSDKNVYVWS-ATGDLRYVLPGHEGSVNHVDFHPHQDIILS 327 Query: 469 ASRDRTIKL 495 S DRTI L Sbjct: 328 CSSDRTIFL 336 Score = 42.7 bits (99), Expect = 7e-04 Identities = 37/142 (26%), Positives = 63/142 (44%), Gaps = 3/142 (2%) Frame = +1 Query: 112 MRGHN-DVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 M GH +V+ A P + + S D+ +L+W++ ++ YGV L G Sbjct: 46 MFGHTAEVLVARFDP--SGSYFASGGMDRQILLWNVFGDVK-------NYGV----LNGC 92 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSV-AFSIDNRQIV 465 + D+ S D + S D L WD +G R+ GH V ++ + + + Sbjct: 93 KGAITDLQWSRDSRVVYCSSSDTHLMSWDAVSGQKIRKHKGHAGVVNALDVLKVGSELLT 152 Query: 466 SASRDRTIKLWNTLG-ECKYTI 528 S S D T+K+W++ +C TI Sbjct: 153 SVSDDCTMKVWDSRSKDCIKTI 174 Score = 31.2 bits (69), Expect = 2.0 Identities = 15/44 (34%), Positives = 18/44 (40%) Frame = +1 Query: 388 VTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNTLGECK 519 V + GH +VL F S DR I LWN G+ K Sbjct: 41 VPNLQMFGHTAEVLVARFDPSGSYFASGGMDRQILLWNVFGDVK 84 Score = 31.2 bits (69), Expect = 2.0 Identities = 20/88 (22%), Positives = 40/88 (45%), Gaps = 1/88 (1%) Frame = +1 Query: 247 SSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFV-GHEKD 423 +S+ VP ++ GH V G + SG D ++ LW++ V + G + Sbjct: 36 TSDLNVPNLQMFGHTAEVLVARFDPSGSYFASGGMDRQILLWNVFGDVKNYGVLNGCKGA 95 Query: 424 VLSVAFSIDNRQIVSASRDRTIKLWNTL 507 + + +S D+R + +S D + W+ + Sbjct: 96 ITDLQWSRDSRVVYCSSSDTHLMSWDAV 123
>WDR39_HUMAN (O76071) WD-repeat protein 39 (Ciao 1 protein)| Length = 339 Score = 53.1 bits (126), Expect = 5e-07 Identities = 40/141 (28%), Positives = 64/141 (45%), Gaps = 3/141 (2%) Frame = +1 Query: 85 QESLVYAGVMRGHNDVVTAIA-TPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYG 261 Q+ + GH + V ++A P N + + SRDKS+ VW++ D EY Sbjct: 92 QDDFECVTTLEGHENEVKSVAWAPSGN--LLATCSRDKSVWVWEV--------DEEDEYE 141 Query: 262 VPFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLW--DLSTGVTTRRFVGHEKDVLSV 435 L H V+ VV + S S+D ++L+ + V GHE V S+ Sbjct: 142 C-VSVLNSHTQDVKHVVWHPSQELLASASYDDTVKLYREEEDDWVCCATLEGHESTVWSL 200 Query: 436 AFSIDNRQIVSASRDRTIKLW 498 AF +++ S S DRT+++W Sbjct: 201 AFDPSGQRLASCSDDRTVRIW 221 Score = 44.3 bits (103), Expect = 2e-04 Identities = 37/150 (24%), Positives = 60/150 (40%), Gaps = 4/150 (2%) Frame = +1 Query: 85 QESLVYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGV 264 ++SLV G + H D + S D+ + +W + SE Sbjct: 2 KDSLVLLGRVPAHPDSRCWFLAWNPAGTLLASCGGDRRIRIWGTEGDSWICKSVLSE--- 58 Query: 265 PFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTG----VTTRRFVGHEKDVLS 432 GH V+ V S G + S S+D +W + VTT GHE +V S Sbjct: 59 ------GHQRTVRKVAWSPCGNYLASASFDATTCIWKKNQDDFECVTTLE--GHENEVKS 110 Query: 433 VAFSIDNRQIVSASRDRTIKLWNTLGECKY 522 VA++ + + SRD+++ +W E +Y Sbjct: 111 VAWAPSGNLLATCSRDKSVWVWEVDEEDEY 140
>POF1_SCHPO (P87053) F-box/WD-repeat protein pof1 (Skp1-binding protein 1)| Length = 605 Score = 53.1 bits (126), Expect = 5e-07 Identities = 41/147 (27%), Positives = 65/147 (44%), Gaps = 1/147 (0%) Frame = +1 Query: 109 VMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 ++ GH D V + +S +VS S D ++ +W + + T L GH Sbjct: 348 ILHGHTDSVLCLTF---DSTLLVSGSADCTVKLWHFSGGKRIT-------------LRGH 391 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVS 468 V V + D LSGS D +++W L T F H V S+A + + ++ S Sbjct: 392 TGPVNSVRIIRDRGLVLSGSDDSTIKIWSLETNTCLHTFSAHIGPVQSLALA--DSRLFS 449 Query: 469 ASRDRTIKLWN-TLGECKYTIGGDLGG 546 S D TIK W+ +C +T+ G + G Sbjct: 450 CSLDGTIKQWDIEKKKCVHTLFGHIEG 476 Score = 50.8 bits (120), Expect = 2e-06 Identities = 42/145 (28%), Positives = 62/145 (42%) Frame = +1 Query: 109 VMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 V+ GH+D V + + + S S D ++ +W+L Q L GH Sbjct: 268 VLSGHSDGVMCLQLVRN---ILASGSYDATIRLWNLATFQQVAL------------LEGH 312 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVS 468 V L D +SGS D +R+W+ T GH VL + F D+ +VS Sbjct: 313 SSGV--TCLQFDQCKLISGSMDKTIRIWNYRTSECISILHGHTDSVLCLTF--DSTLLVS 368 Query: 469 ASRDRTIKLWNTLGECKYTIGGDLG 543 S D T+KLW+ G + T+ G G Sbjct: 369 GSADCTVKLWHFSGGKRITLRGHTG 393 Score = 46.6 bits (109), Expect = 5e-05 Identities = 32/82 (39%), Positives = 43/82 (52%), Gaps = 10/82 (12%) Frame = +1 Query: 286 HGHFVQDVVLS--SDGQFAL--------SGSWDGELRLWDLSTGVTTRRFVGHEKDVLSV 435 HG Q VVLS SDG L SGS+D +RLW+L+T GH V + Sbjct: 261 HGRCRQ-VVLSGHSDGVMCLQLVRNILASGSYDATIRLWNLATFQQVALLEGHSSGVTCL 319 Query: 436 AFSIDNRQIVSASRDRTIKLWN 501 F D +++S S D+TI++WN Sbjct: 320 QF--DQCKLISGSMDKTIRIWN 339 Score = 45.8 bits (107), Expect = 8e-05 Identities = 34/139 (24%), Positives = 59/139 (42%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 +RGH V ++ D ++S S D ++ +W L E + H Sbjct: 388 LRGHTGPVNSVRIIRDRG-LVLSGSDDSTIKIWSL------------ETNTCLHTFSAHI 434 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSA 471 VQ + L+ F S S DG ++ WD+ GH + V +A D+ +++S Sbjct: 435 GPVQSLALADSRLF--SCSLDGTIKQWDIEKKKCVHTLFGHIEGVWEIA--ADHLRLISG 490 Query: 472 SRDRTIKLWNTLGECKYTI 528 + D +K+W EC +T+ Sbjct: 491 AHDGVVKVWEAC-ECVHTL 508
>A16L1_HUMAN (Q676U5) Autophagy-related protein 16-1 (APG16-like 1)| Length = 607 Score = 53.1 bits (126), Expect = 5e-07 Identities = 27/75 (36%), Positives = 38/75 (50%) Frame = +1 Query: 277 LTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNR 456 L+G + + S G + L+ S D R+W + GH VLS F +DN Sbjct: 362 LSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNA 421 Query: 457 QIVSASRDRTIKLWN 501 +IVS S DRT+KLW+ Sbjct: 422 RIVSGSHDRTLKLWD 436 Score = 40.0 bits (92), Expect = 0.004 Identities = 34/112 (30%), Positives = 50/112 (44%), Gaps = 3/112 (2%) Frame = +1 Query: 172 IVSSSRDKSLLVWDL-TNPIQATQDTSS-EYGVPFRRLTGHGHFVQDVVLSSDGQFALSG 345 ++S SRD L V DL TN I+ T + G + R VV S DG + +G Sbjct: 503 LLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTR----------VVFSPDGSYVAAG 552 Query: 346 SWDGELRLWDLSTGVTTRRF-VGHEKDVLSVAFSIDNRQIVSASRDRTIKLW 498 S +G L +W + TG + H + +VA+S +VS + LW Sbjct: 553 SAEGSLYIWSVLTGKVEKVLSKQHSSSINAVAWSPSGSHVVSVDKGCKAVLW 604 Score = 37.0 bits (84), Expect = 0.037 Identities = 36/144 (25%), Positives = 61/144 (42%), Gaps = 2/144 (1%) Frame = +1 Query: 88 ESLVYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVP 267 E + G + G N +T+I S +++++S D + +W T +Y + Sbjct: 354 EKCEFKGSLSGSNAGITSIEFDSAGS-YLLAASNDFASRIW-----------TVDDYRLR 401 Query: 268 FRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRR-FVGHE-KDVLSVAF 441 LTGH V D +SGS D L+LWDL + V + F G D++ Sbjct: 402 -HTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTVFAGSSCNDIVCT-- 458 Query: 442 SIDNRQIVSASRDRTIKLWNTLGE 513 + ++S D+ I+ W+ E Sbjct: 459 ---EQCVMSGHFDKKIRFWDIRSE 479
>GBB3_HUMAN (P16520) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 3 (Transducin beta chain 3) Length = 340 Score = 53.1 bits (126), Expect = 5e-07 Identities = 30/110 (27%), Positives = 50/110 (45%) Frame = +1 Query: 172 IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSW 351 IV+SS D + +WD+ Q T GH + +S D +SG+ Sbjct: 157 IVTSSGDTTCALWDIETGQQKTV------------FVGHTGDCMSLAVSPDFNLFISGAC 204 Query: 352 DGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN 501 D +LWD+ G + F GHE D+ ++ F + I + S D + +L++ Sbjct: 205 DASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFD 254 Score = 53.1 bits (126), Expect = 5e-07 Identities = 51/176 (28%), Positives = 70/176 (39%), Gaps = 35/176 (19%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWD--LTNPIQATQDTSS----------- 252 +RGH + A+ D S +VS+S+D L+VWD TN + A SS Sbjct: 51 LRGHLAKIYAMHWATD-SKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109 Query: 253 --------------------EYGVPF-RRLTGHGHFVQDVVLSSDGQFALSGSWDGELRL 369 E V R L+ H ++ D S S D L Sbjct: 110 NFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTS-SGDTTCAL 168 Query: 370 WDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNTL-GECKYTIGG 534 WD+ TG FVGH D +S+A S D +S + D + KLW+ G C+ T G Sbjct: 169 WDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTG 224 Score = 33.1 bits (74), Expect = 0.54 Identities = 16/68 (23%), Positives = 27/68 (39%) Frame = +1 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASR 477 + V S G+ +G D +WD GH+ V + + D + + S Sbjct: 273 ITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAVATGSW 332 Query: 478 DRTIKLWN 501 D +K+WN Sbjct: 333 DSFLKIWN 340 Score = 32.3 bits (72), Expect = 0.92 Identities = 12/33 (36%), Positives = 22/33 (66%) Frame = +1 Query: 277 LTGHGHFVQDVVLSSDGQFALSGSWDGELRLWD 375 L+GH + V + +++DG +GSWD L++W+ Sbjct: 308 LSGHDNRVSCLGVTADGMAVATGSWDSFLKIWN 340
>WDR12_RAT (P61480) WD-repeat protein 12| Length = 423 Score = 52.8 bits (125), Expect = 7e-07 Identities = 45/144 (31%), Positives = 65/144 (45%), Gaps = 15/144 (10%) Frame = +1 Query: 115 RGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDL------------TNPIQATQDTSSEY 258 RGH V AIA + F S S DK L +W TN + Q T + Sbjct: 186 RGHAGSVDAIAVDSSGTKFC-SGSWDKMLKIWSTVPTDEEDEIQEPTNRPRKKQKTE-QL 243 Query: 259 GV---PFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVL 429 G+ P L+GH + V L SD S SWD +R+WD+ +G G+ K Sbjct: 244 GLTRTPLVTLSGHTEAISSV-LWSDADEVCSASWDHTVRVWDVESGGLKSTLTGN-KVFN 301 Query: 430 SVAFSIDNRQIVSASRDRTIKLWN 501 +++S +++ S S DR I+LW+ Sbjct: 302 CISYSPLCKRLASGSTDRHIRLWD 325 Score = 35.8 bits (81), Expect = 0.083 Identities = 31/136 (22%), Positives = 57/136 (41%), Gaps = 7/136 (5%) Frame = +1 Query: 121 HNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFV 300 H+D +++I + +I+S S DK+ +W L G + GH V Sbjct: 100 HDDWISSIKGAEE---WILSGSYDKTSRIWSLE-------------GKSIMTIVGHTDVV 143 Query: 301 QDVVLSSDGQFA---LSGSWDGELRLWDLSTGVTTRRFV----GHEKDVLSVAFSIDNRQ 459 +DV + L+ S D + LW+ + + + GH V ++A + Sbjct: 144 KDVAWVKKDSLSCLLLTASMDQTILLWEWNIERNKVKALHCCRGHAGSVDAIAVDSSGTK 203 Query: 460 IVSASRDRTIKLWNTL 507 S S D+ +K+W+T+ Sbjct: 204 FCSGSWDKMLKIWSTV 219
>COPB2_CAEEL (Q20168) Probable coatomer subunit beta' (Beta'-coat protein)| (Beta'-COP) Length = 1000 Score = 52.8 bits (125), Expect = 7e-07 Identities = 39/131 (29%), Positives = 61/131 (46%), Gaps = 3/131 (2%) Frame = +1 Query: 118 GHNDVVTAIA-TPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGH 294 GH V IA P DN+ F ++S DK++ VW + VP L GH Sbjct: 140 GHTHYVMQIAINPKDNNTF-ATASLDKTVKVWQFGS------------NVPNFTLEGHEK 186 Query: 295 FVQDVVLSSDGQ--FALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVS 468 V V G+ + +SG+ D +++WD + GH ++V SV F + I++ Sbjct: 187 GVNCVDYYHGGEKPYIISGADDHLVKIWDYQNKTCVQTLDGHAQNVSSVCFHPELPLIIT 246 Query: 469 ASRDRTIKLWN 501 S D T++LW+ Sbjct: 247 GSEDSTVRLWH 257 Score = 48.9 bits (115), Expect = 9e-06 Identities = 32/127 (25%), Positives = 55/127 (43%), Gaps = 4/127 (3%) Frame = +1 Query: 166 PFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLS-SDGQFALS 342 P+++SSS D + +WD N Q GH H+V + ++ D + Sbjct: 112 PYVISSSDDMLVKMWDWDNKWAMKQS-----------FEGHTHYVMQIAINPKDNNTFAT 160 Query: 343 GSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAF--SIDNRQIVSASRDRTIKLWNTLGE- 513 S D +++W + V GHEK V V + + I+S + D +K+W+ + Sbjct: 161 ASLDKTVKVWQFGSNVPNFTLEGHEKGVNCVDYYHGGEKPYIISGADDHLVKIWDYQNKT 220 Query: 514 CKYTIGG 534 C T+ G Sbjct: 221 CVQTLDG 227 Score = 32.7 bits (73), Expect = 0.70 Identities = 19/73 (26%), Positives = 30/73 (41%) Frame = +1 Query: 166 PFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSG 345 P+I+S + D + +WD N + L GH V V + ++G Sbjct: 200 PYIISGADDHLVKIWDYQNKTCV------------QTLDGHAQNVSSVCFHPELPLIITG 247 Query: 346 SWDGELRLWDLST 384 S D +RLW +T Sbjct: 248 SEDSTVRLWHANT 260
>KTNB1_ARATH (Q8H0T9) Katanin p80 WD40-containing subunit B1 homolog 1| Length = 837 Score = 52.8 bits (125), Expect = 7e-07 Identities = 30/111 (27%), Positives = 48/111 (43%) Frame = +1 Query: 169 FIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGS 348 F S S D +L +WD+ GH V + + DG++ +SG Sbjct: 115 FFASGSLDTNLKIWDIRKK------------GCIHTYKGHTRGVNVLRFTPDGRWVVSGG 162 Query: 349 WDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN 501 D +++WDL+ G F HE + S+ F + + S DRT+K W+ Sbjct: 163 EDNIVKVWDLTAGKLLTEFKSHEGQIQSLDFHPHEFLLATGSADRTVKFWD 213 Score = 52.0 bits (123), Expect = 1e-06 Identities = 35/129 (27%), Positives = 58/129 (44%), Gaps = 1/129 (0%) Frame = +1 Query: 118 GHNDVVTAIATPIDNSPFIVSS-SRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGH 294 GH+ + ++ D S +V++ + ++ +WDL E R LTGH Sbjct: 57 GHSSGIDSVT--FDASEVLVAAGAASGTIKLWDL------------EEAKIVRTLTGHRS 102 Query: 295 FVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSAS 474 V G+F SGS D L++WD+ + GH + V + F+ D R +VS Sbjct: 103 NCISVDFHPFGEFFASGSLDTNLKIWDIRKKGCIHTYKGHTRGVNVLRFTPDGRWVVSGG 162 Query: 475 RDRTIKLWN 501 D +K+W+ Sbjct: 163 EDNIVKVWD 171 Score = 47.4 bits (111), Expect = 3e-05 Identities = 32/143 (22%), Positives = 53/143 (37%), Gaps = 1/143 (0%) Frame = +1 Query: 121 HNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFV 300 H+ V + +S +V+ D + +W + P L GH + Sbjct: 15 HSAAVNCLKIGRKSSRVLVTGGEDHKVNLWAIGKPNAILS------------LYGHSSGI 62 Query: 301 QDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRD 480 V + +G+ G ++LWDL R GH + +SV F S S D Sbjct: 63 DSVTFDASEVLVAAGAASGTIKLWDLEEAKIVRTLTGHRSNCISVDFHPFGEFFASGSLD 122 Query: 481 RTIKLWNTLGE-CKYTIGGDLGG 546 +K+W+ + C +T G G Sbjct: 123 TNLKIWDIRKKGCIHTYKGHTRG 145
>PWP2_SCHPO (Q9C1X1) Periodic tryptophan protein 2 homolog| Length = 854 Score = 52.8 bits (125), Expect = 7e-07 Identities = 35/104 (33%), Positives = 49/104 (47%), Gaps = 3/104 (2%) Frame = +1 Query: 247 SSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDV 426 S + G L GH V + +S G SGSWD +R+WD+ + + DV Sbjct: 453 SVQTGQLLETLAGHEGPVSSLSFNSSGSLLASGSWDKTVRIWDIFSRSGIVEPLPIPSDV 512 Query: 427 LSVAFSIDNRQIVSASRDRTIKLWNTL-GECKYTIGG--DLGGG 549 LS+AF D +++ AS D + WN G+ I G DL GG Sbjct: 513 LSLAFHPDGKEVCVASLDGQLTFWNVQEGKQTSLIDGRKDLSGG 556 Score = 49.3 bits (116), Expect = 7e-06 Identities = 28/111 (25%), Positives = 53/111 (47%) Frame = +1 Query: 175 VSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSWD 354 + SS+ LLVW+ + + S H + + SSDGQ ++G+ D Sbjct: 313 IGSSKLGQLLVWEWQSESYVLKQQS------------HYDALSTLQYSSDGQRIITGADD 360 Query: 355 GELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNTL 507 G++++WD+++G F H V + FS + S+S D +++ W+ + Sbjct: 361 GKIKVWDMNSGFCIVTFTQHTSAVSGLCFSKRGNVLFSSSLDGSVRAWDLI 411 Score = 45.8 bits (107), Expect = 8e-05 Identities = 30/112 (26%), Positives = 48/112 (42%), Gaps = 2/112 (1%) Frame = +1 Query: 172 IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHF-VQDVVLSSDGQFALSGS 348 + SSS D S+ WDL FR T + + G+ +GS Sbjct: 396 LFSSSLDGSVRAWDLIRYRN------------FRTFTAPSRVQFSCIAVDPSGEIVCAGS 443 Query: 349 WDG-ELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN 501 D E+ +W + TG GHE V S++F+ + S S D+T+++W+ Sbjct: 444 QDSFEIFMWSVQTGQLLETLAGHEGPVSSLSFNSSGSLLASGSWDKTVRIWD 495 Score = 38.9 bits (89), Expect = 0.010 Identities = 30/107 (28%), Positives = 47/107 (43%), Gaps = 2/107 (1%) Frame = +1 Query: 184 SRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSWDGEL 363 S K + VW N ++ + V R TGH + + S+D +F +S S D Sbjct: 114 SLGKLIQVWRTPNSLEEREFAPF---VLHREYTGHFDDIVSISWSADSRFFISTSKDLTA 170 Query: 364 RLWDLST--GVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLW 498 RL + G GH+ V+S FS D + I + S+D + +W Sbjct: 171 RLHSVDPIEGFHPCALTGHKNTVVSGFFSKDQQTIYTVSKDGALFVW 217 Score = 30.0 bits (66), Expect = 4.5 Identities = 15/69 (21%), Positives = 37/69 (53%), Gaps = 1/69 (1%) Frame = +1 Query: 298 VQDVVLSSDGQF-ALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSAS 474 + + ++S G + A+ S G+L +W+ + + H + ++ +S D ++I++ + Sbjct: 299 IDTLTVNSTGDWIAIGSSKLGQLLVWEWQSESYVLKQQSHYDALSTLQYSSDGQRIITGA 358 Query: 475 RDRTIKLWN 501 D IK+W+ Sbjct: 359 DDGKIKVWD 367
>PWP2_YEAST (P25635) Periodic tryptophan protein 2 (U3 small nucleolar| RNA-associated protein 1) (U3 snoRNA-associated protein 1) Length = 923 Score = 52.8 bits (125), Expect = 7e-07 Identities = 47/173 (27%), Positives = 77/173 (44%), Gaps = 32/173 (18%) Frame = +1 Query: 88 ESLVYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQAT---QDTSSEY 258 +S Y +GH D ++A D S +V++S D + VWD+T+ + TSS Sbjct: 333 QSESYILKQQGHFDSTNSLAYSPDGSR-VVTASEDGKIKVWDITSGFCLATFEEHTSSVT 391 Query: 259 GVPFRR------------------LTGHGHF--------VQDVVLSSD--GQFALSGSWD 354 V F + L + +F +Q L+ D G+ +GS D Sbjct: 392 AVQFAKRGQVMFSSSLDGTVRAWDLIRYRNFRTFTGTERIQFNCLAVDPSGEVVCAGSLD 451 Query: 355 G-ELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNTLG 510 ++ +W + TG GHE V ++FS +N + SAS D+TI++W+ G Sbjct: 452 NFDIHVWSVQTGQLLDALSGHEGPVSCLSFSQENSVLASASWDKTIRIWSIFG 504 Score = 40.0 bits (92), Expect = 0.004 Identities = 25/84 (29%), Positives = 40/84 (47%), Gaps = 6/84 (7%) Frame = +1 Query: 265 PFRRLTGH-GHF--VQDVVLSSDGQFALSGSWDGELRLWDLST---GVTTRRFVGHEKDV 426 PF R H GHF + + S D +F L+ S D ++W + + + F GH V Sbjct: 135 PFVRHRVHAGHFQDITSLTWSQDSRFILTTSKDLSAKIWSVDSEEKNLAATTFNGHRDYV 194 Query: 427 LSVAFSIDNRQIVSASRDRTIKLW 498 + FS D +I + S+D + +W Sbjct: 195 MGAFFSHDQEKIYTVSKDGAVFVW 218 Score = 34.7 bits (78), Expect = 0.18 Identities = 24/78 (30%), Positives = 41/78 (52%), Gaps = 2/78 (2%) Frame = +1 Query: 298 VQDVVLSSDGQFALSGSWD-GELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSAS 474 V V ++ G++ GS G+L +++ + + GH S+A+S D ++V+AS Sbjct: 305 VNTVSVNQTGEWLAFGSSKLGQLLVYEWQSESYILKQQGHFDSTNSLAYSPDGSRVVTAS 364 Query: 475 RDRTIKLWN-TLGECKYT 525 D IK+W+ T G C T Sbjct: 365 EDGKIKVWDITSGFCLAT 382 Score = 33.5 bits (75), Expect = 0.41 Identities = 16/44 (36%), Positives = 27/44 (61%) Frame = +1 Query: 388 VTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNTLGECK 519 V R GH +D+ S+ +S D+R I++ S+D + K+W+ E K Sbjct: 137 VRHRVHAGHFQDITSLTWSQDSRFILTTSKDLSAKIWSVDSEEK 180 Score = 33.1 bits (74), Expect = 0.54 Identities = 23/91 (25%), Positives = 40/91 (43%) Frame = +1 Query: 109 VMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 V GH +T++ D S FI+++S+D S +W + S E + GH Sbjct: 141 VHAGHFQDITSLTWSQD-SRFILTTSKDLSAKIWSVD---------SEEKNLAATTFNGH 190 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDLS 381 +V S D + + S DG + +W+ + Sbjct: 191 RDYVMGAFFSHDQEKIYTVSKDGAVFVWEFT 221
>A16L1_MOUSE (Q8C0J2) Autophagy-related protein 16-1 (APG16-like 1)| Length = 607 Score = 52.8 bits (125), Expect = 7e-07 Identities = 27/75 (36%), Positives = 38/75 (50%) Frame = +1 Query: 277 LTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNR 456 L+G + + S G + L+ S D R+W + GH VLS F +DN Sbjct: 362 LSGSNAGITSIEFDSAGAYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNA 421 Query: 457 QIVSASRDRTIKLWN 501 +IVS S DRT+KLW+ Sbjct: 422 RIVSGSHDRTLKLWD 436 Score = 39.7 bits (91), Expect = 0.006 Identities = 31/128 (24%), Positives = 60/128 (46%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 + GH+ V + +DN+ IVS S D++L +WDL + + + G Sbjct: 404 LTGHSGKVLSAKFLLDNAR-IVSGSHDRTLKLWDLRSKVCI-------------KTVFAG 449 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSA 471 D+V + Q +SG +D ++R WD+ + R K + ++ + + +++S Sbjct: 450 SSCNDIVCTE--QCVMSGHFDKKIRFWDIRSESVVREMELLGK-ITALDLNPERTELLSC 506 Query: 472 SRDRTIKL 495 SRD +K+ Sbjct: 507 SRDDLLKV 514 Score = 38.5 bits (88), Expect = 0.013 Identities = 32/112 (28%), Positives = 50/112 (44%), Gaps = 3/112 (2%) Frame = +1 Query: 172 IVSSSRDKSLLVWDL-TNPIQATQDTSS-EYGVPFRRLTGHGHFVQDVVLSSDGQFALSG 345 ++S SRD L V DL TN ++ T + G + R VV S DG + +G Sbjct: 503 LLSCSRDDLLKVIDLRTNAVKQTFSAPGFKCGSDWTR----------VVFSPDGSYVAAG 552 Query: 346 SWDGELRLWDLSTGVTTRRF-VGHEKDVLSVAFSIDNRQIVSASRDRTIKLW 498 S +G L +W + TG + H + +VA++ +VS + LW Sbjct: 553 SAEGSLYVWSVLTGKVEKVLSKQHSSSINAVAWAPSGLHVVSVDKGSRAVLW 604 Score = 35.0 bits (79), Expect = 0.14 Identities = 34/140 (24%), Positives = 60/140 (42%), Gaps = 2/140 (1%) Frame = +1 Query: 100 YAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRL 279 + G + G N +T+I + +++++S D + +W T +Y + L Sbjct: 358 FKGSLSGSNAGITSIEFDSAGA-YLLAASNDFASRIW-----------TVDDYRLR-HTL 404 Query: 280 TGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRR-FVGHE-KDVLSVAFSIDN 453 TGH V D +SGS D L+LWDL + V + F G D++ Sbjct: 405 TGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTVFAGSSCNDIVCT-----E 459 Query: 454 RQIVSASRDRTIKLWNTLGE 513 + ++S D+ I+ W+ E Sbjct: 460 QCVMSGHFDKKIRFWDIRSE 479
>WDR12_HUMAN (Q9GZL7) WD-repeat protein 12 (YTM1 homolog)| Length = 423 Score = 52.4 bits (124), Expect = 9e-07 Identities = 45/144 (31%), Positives = 67/144 (46%), Gaps = 15/144 (10%) Frame = +1 Query: 115 RGHNDVVTAIATPIDNSPFIVSSSRDKSLLVW------------DLTNPIQATQDTSSEY 258 RGH V +IA + F S S DK L +W + TN + Q T + Sbjct: 186 RGHAGSVDSIAVDGSGTKFC-SGSWDKMLKIWSTVPTDEEDEMEESTNRPRKKQKTE-QL 243 Query: 259 GV---PFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVL 429 G+ P L+GH V V L SD + S SWD +R+WD+ +G G+ K Sbjct: 244 GLTRTPIVTLSGHMEAVSSV-LWSDAEEICSASWDHTIRVWDVESGSLKSTLTGN-KVFN 301 Query: 430 SVAFSIDNRQIVSASRDRTIKLWN 501 +++S +++ S S DR I+LW+ Sbjct: 302 CISYSPLCKRLASGSTDRHIRLWD 325 Score = 41.6 bits (96), Expect = 0.002 Identities = 39/135 (28%), Positives = 62/135 (45%), Gaps = 4/135 (2%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 + GH + V+++ ++ I S+S D ++ VWD+ E G LTG+ Sbjct: 253 LSGHMEAVSSVLW--SDAEEICSASWDHTIRVWDV------------ESGSLKSTLTGNK 298 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLST---GVTTRRFVGHEKDVLSVAFS-IDNRQ 459 F + S + SGS D +RLWD T + + H V SV +S +Q Sbjct: 299 VF-NCISYSPLCKRLASGSTDRHIRLWDPRTKDGSLVSLSLTSHTGWVTSVKWSPTHEQQ 357 Query: 460 IVSASRDRTIKLWNT 504 ++S S D +KLW+T Sbjct: 358 LISGSLDNIVKLWDT 372 Score = 36.6 bits (83), Expect = 0.049 Identities = 28/107 (26%), Positives = 43/107 (40%), Gaps = 7/107 (6%) Frame = +1 Query: 208 WDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFA---LSGSWDGELRLWDL 378 W LT T S G + GH V+DV + LS S D + LW+ Sbjct: 113 WILTGSYDKTSRIWSLEGKSIMTIVGHTDVVKDVAWVKKDSLSCLLLSASMDQTILLWEW 172 Query: 379 STGVTTRRFV----GHEKDVLSVAFSIDNRQIVSASRDRTIKLWNTL 507 + + + GH V S+A + S S D+ +K+W+T+ Sbjct: 173 NVERNKVKALHCCRGHAGSVDSIAVDGSGTKFCSGSWDKMLKIWSTV 219 Score = 35.4 bits (80), Expect = 0.11 Identities = 27/73 (36%), Positives = 38/73 (52%), Gaps = 5/73 (6%) Frame = +1 Query: 295 FVQDVVLSSDG--QFALSGSWDGELRLWDLSTGVTTRRFVGHE---KDVLSVAFSIDNRQ 459 F D + S G ++ L+GS+D R+W L G + VGH KDV V + Sbjct: 99 FHDDWISSIKGAEEWILTGSYDKTSRIWSLE-GKSIMTIVGHTDVVKDVAWVKKDSLSCL 157 Query: 460 IVSASRDRTIKLW 498 ++SAS D+TI LW Sbjct: 158 LLSASMDQTILLW 170
>YTM1_YEAST (Q12024) Microtubule-associated protein YTM1| Length = 460 Score = 52.4 bits (124), Expect = 9e-07 Identities = 26/70 (37%), Positives = 43/70 (61%) Frame = +1 Query: 295 FVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSAS 474 +V + + + +SGS+DG +R WDLS G +++ GH + +V + I N ++VSA Sbjct: 105 WVSSLDVGDGSKHIISGSYDGIVRTWDLS-GNVQKQYSGHSGPIRAVKY-ISNTRLVSAG 162 Query: 475 RDRTIKLWNT 504 DRT++LW T Sbjct: 163 NDRTLRLWKT 172 Score = 43.9 bits (102), Expect = 3e-04 Identities = 37/140 (26%), Positives = 60/140 (42%), Gaps = 23/140 (16%) Frame = +1 Query: 157 DNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFA 336 D S I+S S D + WDL+ +Q ++ +GH ++ V S+ + Sbjct: 113 DGSKHIISGSYDGIVRTWDLSGNVQ-------------KQYSGHSGPIRAVKYISNTRLV 159 Query: 337 LSGSWDGELRLW-----------------------DLSTGVTTRRFVGHEKDVLSVAFSI 447 +G+ D LRLW ++ G T GH+ V+S+ S Sbjct: 160 SAGN-DRTLRLWKTKNDDLKLTSQQQAQEDDDDEVNIEDGKTLAILEGHKAPVVSIDVS- 217 Query: 448 DNRQIVSASRDRTIKLWNTL 507 DN +I+SAS D +I W+T+ Sbjct: 218 DNSRILSASYDNSIGFWSTI 237 Score = 34.7 bits (78), Expect = 0.18 Identities = 23/83 (27%), Positives = 44/83 (53%), Gaps = 8/83 (9%) Frame = +1 Query: 271 RRLTGHGHFVQDVVLSSDGQFAL-SGSWDGELRLWDLSTG----VTTRRFVGHEKDVLSV 435 ++L GH +FV + + ++ L SGS DG +++WD+ + TR +K V Sbjct: 369 QQLIGHKNFVSSLDTCPENEYILCSGSHDGTVKVWDVRSTSPMYTITREDKSVQKGVNDK 428 Query: 436 AFSI---DNRQIVSASRDRTIKL 495 F++ + I+SA +D+ I++ Sbjct: 429 VFAVKWAEKVGIISAGQDKKIQI 451 Score = 30.8 bits (68), Expect = 2.7 Identities = 23/78 (29%), Positives = 40/78 (51%), Gaps = 8/78 (10%) Frame = +1 Query: 55 SLRHTTM----AGAQESLVYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDL-- 216 S RH T+ GA + ++ GH + V+++ T +N + S S D ++ VWD+ Sbjct: 349 SARHITLHDPRVGASSKVTQQQLI-GHKNFVSSLDTCPENEYILCSGSHDGTVKVWDVRS 407 Query: 217 TNPIQ--ATQDTSSEYGV 264 T+P+ +D S + GV Sbjct: 408 TSPMYTITREDKSVQKGV 425
>FZR_HUMAN (Q9UM11) Fizzy-related protein homolog (Fzr) (Cdh1/Hct1 homolog)| (hCDH1) (CDC20-like protein 1) Length = 496 Score = 52.4 bits (124), Expect = 9e-07 Identities = 41/137 (29%), Positives = 69/137 (50%), Gaps = 4/137 (2%) Frame = +1 Query: 109 VMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDL-TNPIQATQDTSSEYGVPFRRLTG 285 ++ GH V A+A N+ + S SRD+ +L D+ T P+Q+ RRL G Sbjct: 266 MLEGHTARVGALAW---NAEQLSSGSRDRMILQRDIRTPPLQSE-----------RRLQG 311 Query: 286 HGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIV 465 H V + S+D Q SG D +L +W+ S+ +++ H V ++A+S ++ Sbjct: 312 HRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLL 371 Query: 466 SA---SRDRTIKLWNTL 507 ++ + DR I+ WNTL Sbjct: 372 ASGGGTADRCIRFWNTL 388 Score = 35.8 bits (81), Expect = 0.083 Identities = 16/61 (26%), Positives = 28/61 (45%) Frame = +1 Query: 343 GSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNTLGECKY 522 G ++ +W + + GH VL +A S D IV+ + D T++ WN + + Sbjct: 419 GYSQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRS 478 Query: 523 T 525 T Sbjct: 479 T 479 Score = 33.9 bits (76), Expect = 0.31 Identities = 22/71 (30%), Positives = 34/71 (47%) Frame = +1 Query: 277 LTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNR 456 L+ G V V S G G+ G +++WD + G GH V ++A++ + Sbjct: 225 LSVEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAE-- 282 Query: 457 QIVSASRDRTI 489 Q+ S SRDR I Sbjct: 283 QLSSGSRDRMI 293 Score = 32.7 bits (73), Expect = 0.70 Identities = 15/54 (27%), Positives = 30/54 (55%) Frame = +1 Query: 274 RLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSV 435 +LTGH + V + +S DG+ ++G+ D LR W++ + + + VL++ Sbjct: 438 KLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRSTKVKWESVSVLNL 491
>POP3_SCHPO (O74184) WD-repeat protein pop3 (WD-repeat protein wat1)| Length = 314 Score = 52.4 bits (124), Expect = 9e-07 Identities = 30/78 (38%), Positives = 43/78 (55%) Frame = +1 Query: 211 DLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGV 390 D T I +T+D S RRL GH +V D S+D + ++ S D RLW+LS+G Sbjct: 236 DATVNIWSTEDMSFMLE---RRLQGHQRWVWDCAFSADSTYLVTASSDHVARLWELSSGE 292 Query: 391 TTRRFVGHEKDVLSVAFS 444 T R++ GH K + VA + Sbjct: 293 TIRQYSGHHKAAVCVALN 310 Score = 47.0 bits (110), Expect = 4e-05 Identities = 30/123 (24%), Positives = 61/123 (49%), Gaps = 2/123 (1%) Frame = +1 Query: 139 AIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLS 318 ++ P +S +VSS D ++ W+ + G+ R + V + +S Sbjct: 2 SVQYPPQHSVLLVSSGYDHTIRFWEALS------------GICSRTIQHADSQVNRLCIS 49 Query: 319 SDGQFALSGSWDGELRLWDLSTG--VTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIK 492 D +F L+ + + +RL+D++T + F GH +V ++AF D + + ++S D T+K Sbjct: 50 PDKKF-LAAAGNPHVRLYDINTSSQMPLMTFEGHTNNVTAIAFHCDGKWLATSSEDGTVK 108 Query: 493 LWN 501 +W+ Sbjct: 109 VWD 111 Score = 44.7 bits (104), Expect = 2e-04 Identities = 30/126 (23%), Positives = 54/126 (42%), Gaps = 2/126 (1%) Frame = +1 Query: 127 DVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQD 306 DV + T + +++ + + VW + N + P + H ++ Sbjct: 167 DVPMSSITVGSDGSMLIAGNNKGNCYVWRMLN------HQGASLLQPVVKFQAHQRYITR 220 Query: 307 VVLSSDGQFALSGSWDGELRLWDLS--TGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRD 480 VLS D + + S D + +W + + RR GH++ V AFS D+ +V+AS D Sbjct: 221 CVLSPDVKHLATCSADATVNIWSTEDMSFMLERRLQGHQRWVWDCAFSADSTYLVTASSD 280 Query: 481 RTIKLW 498 +LW Sbjct: 281 HVARLW 286 Score = 40.0 bits (92), Expect = 0.004 Identities = 22/98 (22%), Positives = 45/98 (45%) Frame = +1 Query: 220 NPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTR 399 NP D ++ +P GH + V + DG++ + S DG +++WD+ R Sbjct: 60 NPHVRLYDINTSSQMPLMTFEGHTNNVTAIAFHCDGKWLATSSEDGTVKVWDMRAPSVQR 119 Query: 400 RFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNTLGE 513 + H+ V + + +++S + ++ W+ LGE Sbjct: 120 NY-DHKSPVNDLLIHPNQGELLSCDQSGRVRAWD-LGE 155 Score = 39.7 bits (91), Expect = 0.006 Identities = 35/165 (21%), Positives = 62/165 (37%), Gaps = 36/165 (21%) Frame = +1 Query: 118 GHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNP-IQATQDTSS-------------- 252 GH + VTAIA D ++ +SS D ++ VWD+ P +Q D S Sbjct: 81 GHTNNVTAIAFHCDGK-WLATSSEDGTVKVWDMRAPSVQRNYDHKSPVNDLLIHPNQGEL 139 Query: 253 ---------------EYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDL--- 378 E + + + + SDG ++G+ G +W + Sbjct: 140 LSCDQSGRVRAWDLGENSCTHELIPEEDVPMSSITVGSDGSMLIAGNNKGNCYVWRMLNH 199 Query: 379 ---STGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNT 504 S +F H++ + S D + + + S D T+ +W+T Sbjct: 200 QGASLLQPVVKFQAHQRYITRCVLSPDVKHLATCSADATVNIWST 244
>MORG1_XENTR (Q5XGI5) Mitogen-activated protein kinase organizer 1 (MAPK| organizer 1) Length = 314 Score = 52.4 bits (124), Expect = 9e-07 Identities = 37/123 (30%), Positives = 59/123 (47%) Frame = +1 Query: 133 VTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVV 312 V A+ +D + + ++ DK+L +W NP + T + +GHG+ V D Sbjct: 28 VRAVRFNVDGN-YCMTCGSDKTLKLW---NPHKGTL---------LKTYSGHGYEVLDTA 74 Query: 313 LSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIK 492 S D S S D + LWD++ G R+F GH V V F+ + I+S S D +I+ Sbjct: 75 GSYDNSQMCSCSSDKTVILWDVAQGQVVRKFRGHAGKVNCVQFNEEATVIMSGSIDSSIR 134 Query: 493 LWN 501 W+ Sbjct: 135 CWD 137 Score = 37.7 bits (86), Expect = 0.022 Identities = 34/131 (25%), Positives = 59/131 (45%), Gaps = 4/131 (3%) Frame = +1 Query: 115 RGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTN----PIQATQDTSSEYGVPFRRLT 282 RGH V + + + I+S S D S+ WD + IQ + G+ +++ Sbjct: 106 RGHAGKVNCVQFN-EEATVIMSGSIDSSIRCWDCRSRRPEAIQILDEAKD--GISSIKIS 162 Query: 283 GHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQI 462 H L+GS DG LR +DL G ++G + V+FS D++ + Sbjct: 163 DHE--------------ILAGSVDGNLRRYDLRKGEMCADYLG--SPITCVSFSQDSQCL 206 Query: 463 VSASRDRTIKL 495 +++S D T++L Sbjct: 207 LASSLDSTLRL 217 Score = 37.0 bits (84), Expect = 0.037 Identities = 22/67 (32%), Positives = 30/67 (44%), Gaps = 2/67 (2%) Frame = +1 Query: 307 VVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKD--VLSVAFSIDNRQIVSASRD 480 V S D Q L+ S D LRL D TG + GH+ L S + ++S S D Sbjct: 197 VSFSQDSQCLLASSLDSTLRLLDKDTGELLGEYTGHQNHSYKLDSCLSEKDTHVLSCSED 256 Query: 481 RTIKLWN 501 T+ W+ Sbjct: 257 GTVCFWD 263
>FZR_MOUSE (Q9R1K5) Fizzy-related protein homolog (Fzr) (Cdh1/Hct1 homolog)| Length = 493 Score = 52.4 bits (124), Expect = 9e-07 Identities = 41/137 (29%), Positives = 68/137 (49%), Gaps = 4/137 (2%) Frame = +1 Query: 109 VMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDL-TNPIQATQDTSSEYGVPFRRLTG 285 ++ GH V A+A D + S SRD+ +L D+ T P+Q+ RRL G Sbjct: 266 MLEGHTARVGALAWNADQ---LSSGSRDRMILQRDIRTPPLQSE-----------RRLQG 311 Query: 286 HGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIV 465 H V + S+D Q SG D +L +W+ S+ +++ H V ++A+S ++ Sbjct: 312 HRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLL 371 Query: 466 SA---SRDRTIKLWNTL 507 ++ + DR I+ WNTL Sbjct: 372 ASGGGTADRCIRFWNTL 388 Score = 35.8 bits (81), Expect = 0.083 Identities = 16/61 (26%), Positives = 28/61 (45%) Frame = +1 Query: 343 GSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNTLGECKY 522 G ++ +W + + GH VL +A S D IV+ + D T++ WN + + Sbjct: 419 GYSQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRS 478 Query: 523 T 525 T Sbjct: 479 T 479 Score = 35.4 bits (80), Expect = 0.11 Identities = 23/71 (32%), Positives = 34/71 (47%) Frame = +1 Query: 277 LTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNR 456 L+ G V V S G G+ G +++WD + G GH V ++A++ D Sbjct: 225 LSVEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAD-- 282 Query: 457 QIVSASRDRTI 489 Q+ S SRDR I Sbjct: 283 QLSSGSRDRMI 293 Score = 32.3 bits (72), Expect = 0.92 Identities = 13/35 (37%), Positives = 23/35 (65%) Frame = +1 Query: 274 RLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDL 378 +LTGH + V + +S DG+ ++G+ D LR W++ Sbjct: 438 KLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNV 472
>WDR71_CHICK (Q5ZK69) WD-repeat protein 71| Length = 392 Score = 52.0 bits (123), Expect = 1e-06 Identities = 32/109 (29%), Positives = 46/109 (42%) Frame = +1 Query: 175 VSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSWD 354 VS+S D ++ +W N G R L GH + V G LSG D Sbjct: 108 VSTSTDGTMKIWQAAN------------GEIRRLLEGHVYDVNCCRFFPSGLVVLSGGMD 155 Query: 355 GELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN 501 +L++W F GH+ +L A R ++S SRD T +LW+ Sbjct: 156 AQLKIWSAEDASCVVTFKGHKGGILDTAIVDRGRNVLSCSRDGTARLWD 204 Score = 45.4 bits (106), Expect = 1e-04 Identities = 32/128 (25%), Positives = 55/128 (42%), Gaps = 2/128 (1%) Frame = +1 Query: 169 FIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTG-HGHFVQDVVLSSDGQFALSG 345 F+V KS+L+ ++ S+++ P+ + H + + +SS G +S Sbjct: 57 FVVGEVTKKSILI------SCPHENVSTKFLAPYTTFSRIHQKSITCLDISSGGGLGVST 110 Query: 346 SWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNTL-GECKY 522 S DG +++W + G R GH DV F ++S D +K+W+ C Sbjct: 111 STDGTMKIWQAANGEIRRLLEGHVYDVNCCRFFPSGLVVLSGGMDAQLKIWSAEDASCVV 170 Query: 523 TIGGDLGG 546 T G GG Sbjct: 171 TFKGHKGG 178
>PRP19_RAT (Q9JMJ4) Pre-mRNA-splicing factor 19 (PRP19/PSO4 homolog) (Neuronal| differentiation-related gene protein) Length = 504 Score = 52.0 bits (123), Expect = 1e-06 Identities = 33/131 (25%), Positives = 57/131 (43%) Frame = +1 Query: 109 VMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 V+R H VT ++ +++SSS D+ D+ T+ T G H Sbjct: 301 VVRAHESAVTGLSLHATGD-YLLSSSDDQYWAFSDIQTGRVLTKVTDETSGCSLTCAQFH 359 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVS 468 DG +G+ D ++++WDL F GH + S+AFS + + + Sbjct: 360 ----------PDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLAT 409 Query: 469 ASRDRTIKLWN 501 A+ D ++KLW+ Sbjct: 410 AADDSSVKLWD 420 Score = 38.9 bits (89), Expect = 0.010 Identities = 22/61 (36%), Positives = 30/61 (49%) Frame = +1 Query: 319 SDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLW 498 SD L+G D + ++D ST GH K V SV F + SAS D TI++W Sbjct: 232 SDTNKILTGGADKNVVVFDKSTEQILATLKGHTKKVTSVVFHPSQELVFSASPDATIRIW 291 Query: 499 N 501 + Sbjct: 292 S 292 Score = 33.5 bits (75), Expect = 0.41 Identities = 29/129 (22%), Positives = 55/129 (42%), Gaps = 1/129 (0%) Frame = +1 Query: 118 GHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHF 297 GH+ +T+IA +N ++ +++ D S+ +WDL F+ L +F Sbjct: 390 GHSGPITSIAFS-ENGYYLATAADDSSVKLWDLRKLKN------------FKTLQLDNNF 436 Query: 298 -VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSAS 474 V+ ++ G + G D ++ + T + F H VAF + I S Sbjct: 437 EVKSLIFDQSGTYLALGGTDVQIYICKQWTEIL--HFTEHSGLTTGVAFGHHAKFIASTG 494 Query: 475 RDRTIKLWN 501 DR++K ++ Sbjct: 495 MDRSLKFYS 503 Score = 32.3 bits (72), Expect = 0.92 Identities = 26/105 (24%), Positives = 43/105 (40%), Gaps = 1/105 (0%) Frame = +1 Query: 172 IVSSSRDKSLLVWDL-TNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGS 348 I++ DK+++V+D T I AT L GH V VV + S S Sbjct: 237 ILTGGADKNVVVFDKSTEQILAT-------------LKGHTKKVTSVVFHPSQELVFSAS 283 Query: 349 WDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDR 483 D +R+W + + HE V ++ ++S+S D+ Sbjct: 284 PDATIRIWSVPNTSCVQVVRAHESAVTGLSLHATGDYLLSSSDDQ 328
>PRP19_MOUSE (Q99KP6) Pre-mRNA-splicing factor 19 (PRP19/PSO4 homolog) (Nuclear| matrix protein 200) (Nuclear matrix protein SNEV) Length = 504 Score = 52.0 bits (123), Expect = 1e-06 Identities = 33/131 (25%), Positives = 57/131 (43%) Frame = +1 Query: 109 VMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 V+R H VT ++ +++SSS D+ D+ T+ T G H Sbjct: 301 VVRAHESAVTGLSLHATGD-YLLSSSDDQYWAFSDIQTGRVLTKVTDETSGCSLTCAQFH 359 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVS 468 DG +G+ D ++++WDL F GH + S+AFS + + + Sbjct: 360 ----------PDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLAT 409 Query: 469 ASRDRTIKLWN 501 A+ D ++KLW+ Sbjct: 410 AADDSSVKLWD 420 Score = 38.9 bits (89), Expect = 0.010 Identities = 22/61 (36%), Positives = 30/61 (49%) Frame = +1 Query: 319 SDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLW 498 SD L+G D + ++D ST GH K V SV F + SAS D TI++W Sbjct: 232 SDTNKILTGGADKNVVVFDKSTEQILATLKGHTKKVTSVVFHPSQELVFSASPDATIRIW 291 Query: 499 N 501 + Sbjct: 292 S 292 Score = 33.5 bits (75), Expect = 0.41 Identities = 29/129 (22%), Positives = 55/129 (42%), Gaps = 1/129 (0%) Frame = +1 Query: 118 GHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHF 297 GH+ +T+IA +N ++ +++ D S+ +WDL F+ L +F Sbjct: 390 GHSGPITSIAFS-ENGYYLATAADDSSVKLWDLRKLKN------------FKTLQLDNNF 436 Query: 298 -VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSAS 474 V+ ++ G + G D ++ + T + F H VAF + I S Sbjct: 437 EVKSLIFDQSGTYLALGGTDVQIYICKQWTEIL--HFTEHSGLTTGVAFGHHAKFIASTG 494 Query: 475 RDRTIKLWN 501 DR++K ++ Sbjct: 495 MDRSLKFYS 503 Score = 32.3 bits (72), Expect = 0.92 Identities = 26/105 (24%), Positives = 43/105 (40%), Gaps = 1/105 (0%) Frame = +1 Query: 172 IVSSSRDKSLLVWDL-TNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGS 348 I++ DK+++V+D T I AT L GH V VV + S S Sbjct: 237 ILTGGADKNVVVFDKSTEQILAT-------------LKGHTKKVTSVVFHPSQELVFSAS 283 Query: 349 WDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDR 483 D +R+W + + HE V ++ ++S+S D+ Sbjct: 284 PDATIRIWSVPNTSCVQVVRAHESAVTGLSLHATGDYLLSSSDDQ 328
>PRP19_HUMAN (Q9UMS4) Pre-mRNA-splicing factor 19 (PRP19/PSO4 homolog) (Nuclear| matrix protein 200) (hPso4) Length = 504 Score = 52.0 bits (123), Expect = 1e-06 Identities = 33/131 (25%), Positives = 57/131 (43%) Frame = +1 Query: 109 VMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 V+R H VT ++ +++SSS D+ D+ T+ T G H Sbjct: 301 VVRAHESAVTGLSLHATGD-YLLSSSDDQYWAFSDIQTGRVLTKVTDETSGCSLTCAQFH 359 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVS 468 DG +G+ D ++++WDL F GH + S+AFS + + + Sbjct: 360 ----------PDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLAT 409 Query: 469 ASRDRTIKLWN 501 A+ D ++KLW+ Sbjct: 410 AADDSSVKLWD 420 Score = 36.6 bits (83), Expect = 0.049 Identities = 21/61 (34%), Positives = 30/61 (49%) Frame = +1 Query: 319 SDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLW 498 SD L+G D + ++D S+ GH K V SV F + SAS D TI++W Sbjct: 232 SDTNKILTGGADKNVVVFDKSSEQILATLKGHTKKVTSVVFHPSQDLVFSASPDATIRIW 291 Query: 499 N 501 + Sbjct: 292 S 292 Score = 33.5 bits (75), Expect = 0.41 Identities = 29/129 (22%), Positives = 55/129 (42%), Gaps = 1/129 (0%) Frame = +1 Query: 118 GHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHF 297 GH+ +T+IA +N ++ +++ D S+ +WDL F+ L +F Sbjct: 390 GHSGPITSIAFS-ENGYYLATAADDSSVKLWDLRKLKN------------FKTLQLDNNF 436 Query: 298 -VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSAS 474 V+ ++ G + G D ++ + T + F H VAF + I S Sbjct: 437 EVKSLIFDQSGTYLALGGTDVQIYICKQWTEIL--HFTEHSGLTTGVAFGHHAKFIASTG 494 Query: 475 RDRTIKLWN 501 DR++K ++ Sbjct: 495 MDRSLKFYS 503 Score = 31.2 bits (69), Expect = 2.0 Identities = 25/105 (23%), Positives = 43/105 (40%), Gaps = 1/105 (0%) Frame = +1 Query: 172 IVSSSRDKSLLVWDLTNP-IQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGS 348 I++ DK+++V+D ++ I AT L GH V VV S S Sbjct: 237 ILTGGADKNVVVFDKSSEQILAT-------------LKGHTKKVTSVVFHPSQDLVFSAS 283 Query: 349 WDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDR 483 D +R+W + + HE V ++ ++S+S D+ Sbjct: 284 PDATIRIWSVPNASCVQVVRAHESAVTGLSLHATGDYLLSSSDDQ 328
>PFS2_YEAST (P42841) Protein PFS2| Length = 465 Score = 51.6 bits (122), Expect = 1e-06 Identities = 35/137 (25%), Positives = 61/137 (44%) Frame = +1 Query: 91 SLVYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPF 270 S + +M+ H+ VT + D S +++S D + +W + D + Sbjct: 124 SFTFETLMQAHDSAVTTMKYSHD-SDWMISGDADGMIKIWQPNFSMVKEIDAA------- 175 Query: 271 RRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSID 450 H ++D+ SS+ ++ S D L++W+ S G R GH DV S + + Sbjct: 176 -----HTESIRDMAFSSNDSKFVTCSDDNILKIWNFSNGKQERVLSGHHWDVKSCDWHPE 230 Query: 451 NRQIVSASRDRTIKLWN 501 I SAS+D +KLW+ Sbjct: 231 MGLIASASKDNLVKLWD 247 Score = 31.2 bits (69), Expect = 2.0 Identities = 28/128 (21%), Positives = 54/128 (42%), Gaps = 1/128 (0%) Frame = +1 Query: 121 HNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFV 300 H + + +A ++S F+ S D L +W+ +N G R L+GH V Sbjct: 176 HTESIRDMAFSSNDSKFVTCSD-DNILKIWNFSN------------GKQERVLSGHHWDV 222 Query: 301 QDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSA-SR 477 + + S S D ++LWD +G + + VL F ++ A S+ Sbjct: 223 KSCDWHPEMGLIASASKDNLVKLWDPRSGNCISSILKFKHTVLKTRFQPTKGNLLMAISK 282 Query: 478 DRTIKLWN 501 D++ ++++ Sbjct: 283 DKSCRVFD 290 Score = 30.0 bits (66), Expect = 4.5 Identities = 25/112 (22%), Positives = 51/112 (45%), Gaps = 3/112 (2%) Frame = +1 Query: 172 IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSW 351 +++ S+DKS V+D+ ++ E + L H ++ F L+ + Sbjct: 277 LMAISKDKSCRVFDIRYSMKELMCVRDE--TDYMTLEWHP--------INESMFTLA-CY 325 Query: 352 DGELRLWDLSTGVTTRRFV---GHEKDVLSVAFSIDNRQIVSASRDRTIKLW 498 DG L+ +DL + H+K + S++++ +A++DRTI+ W Sbjct: 326 DGSLKHFDLLQNLNEPILTIPYAHDKCITSLSYNPVGHIFATAAKDRTIRFW 377
>TBL2_HUMAN (Q9Y4P3) Transducin beta-like 2 protein (WS beta-transducin repeats| protein) (WS-betaTRP) (Williams-Beuren syndrome chromosome region 13 protein) Length = 447 Score = 51.6 bits (122), Expect = 1e-06 Identities = 35/125 (28%), Positives = 59/125 (47%), Gaps = 8/125 (6%) Frame = +1 Query: 169 FIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGS 348 FI+++S D ++L+W L + +T +T+ +S G+F S Sbjct: 202 FIMTASSDTTVLIWSLKGQVLSTINTNQMNNT-------------HAAVSPCGRFVASCG 248 Query: 349 WDGELRLWDLSTG--------VTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNT 504 + ++++W++ G V GH V S AFS D+R++ S S+D T KLW+T Sbjct: 249 FTPDVKVWEVCFGKKGEFQEVVRAFELKGHSAAVHSFAFSNDSRRMASVSKDGTWKLWDT 308 Query: 505 LGECK 519 E K Sbjct: 309 DVEYK 313
>A16L1_PONPY (Q5RAC9) Autophagy-related protein 16-1 (APG16-like 1)| Length = 607 Score = 51.6 bits (122), Expect = 1e-06 Identities = 26/75 (34%), Positives = 37/75 (49%) Frame = +1 Query: 277 LTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNR 456 L+G + + S G + L+ S D R+W + GH VLS F +DN Sbjct: 362 LSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDSRLRHTLTGHSGKVLSAKFLLDNA 421 Query: 457 QIVSASRDRTIKLWN 501 +IVS S DRT+K W+ Sbjct: 422 RIVSGSHDRTLKHWD 436 Score = 38.5 bits (88), Expect = 0.013 Identities = 34/112 (30%), Positives = 49/112 (43%), Gaps = 3/112 (2%) Frame = +1 Query: 172 IVSSSRDKSLLVWDL-TNPIQATQDTSS-EYGVPFRRLTGHGHFVQDVVLSSDGQFALSG 345 ++S SRD L V DL TN I+ T + G + R VV S DG + +G Sbjct: 503 LLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTR----------VVFSPDGSYVAAG 552 Query: 346 SWDGELRLWDLSTGVTTRRF-VGHEKDVLSVAFSIDNRQIVSASRDRTIKLW 498 S +G L W + TG + H + +VA+S +VS + LW Sbjct: 553 SAEGSLYTWSVLTGKVEKVLSKQHSSSINAVAWSPSGLHVVSVDKGCKAVLW 604 Score = 33.1 bits (74), Expect = 0.54 Identities = 34/144 (23%), Positives = 60/144 (41%), Gaps = 2/144 (1%) Frame = +1 Query: 88 ESLVYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVP 267 E + G + G N +T+I S +++++S D + +W + D+ + Sbjct: 354 EKCEFKGSLSGSNAGITSIEFDSAGS-YLLAASNDFASRIWTV-------DDSRLRH--- 402 Query: 268 FRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRR-FVGHE-KDVLSVAF 441 LTGH V D +SGS D L+ WDL + V + F G D++ Sbjct: 403 --TLTGHSGKVLSAKFLLDNARIVSGSHDRTLKHWDLRSKVCIKTVFAGSSCNDIVCT-- 458 Query: 442 SIDNRQIVSASRDRTIKLWNTLGE 513 + ++S D+ I+ W+ E Sbjct: 459 ---EQCVMSGHFDKKIRFWDIRSE 479
>YGA4_YEAST (P53196) Hypothetical 46.4 kDa Trp-Asp repeats-containing protein| in PMC1-TFG2 intergenic region Length = 417 Score = 51.2 bits (121), Expect = 2e-06 Identities = 41/131 (31%), Positives = 62/131 (47%), Gaps = 6/131 (4%) Frame = +1 Query: 172 IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSW 351 ++SSS+D L +W + + G R L GH V D+ + G+ LS S Sbjct: 151 LISSSQDMQLKIWSVKD------------GSNPRTLIGHRATVTDIAIIDRGRNVLSASL 198 Query: 352 DGELRLWDLSTGVTTRRFVGHEK---DVLSVAFSI-DNRQI--VSASRDRTIKLWNTLGE 513 DG +RLW+ TG T F E V S+A + +RQ+ +S S+ ++ + T G Sbjct: 199 DGTIRLWECGTGTTIHTFNRKENPHDGVNSIALFVGTDRQLHEISTSKKNNLE-FGTYG- 256 Query: 514 CKYTIGGDLGG 546 KY I G + G Sbjct: 257 -KYVIAGHVSG 266 Score = 47.4 bits (111), Expect = 3e-05 Identities = 21/58 (36%), Positives = 32/58 (55%) Frame = +1 Query: 325 GQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLW 498 G+ +S S D +L++W + G R +GH V +A R ++SAS D TI+LW Sbjct: 148 GEALISSSQDMQLKIWSVKDGSNPRTLIGHRATVTDIAIIDRGRNVLSASLDGTIRLW 205
>YB1C_SCHPO (P87177) Hypothetical WD-repeat protein C3D6.12 in chromosome II| Length = 922 Score = 51.2 bits (121), Expect = 2e-06 Identities = 34/143 (23%), Positives = 68/143 (47%), Gaps = 4/143 (2%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 ++ H+ + +A D + F +S+ D ++ +W L + T+ + T Sbjct: 473 IQAHDGAIWDLAVGHDGTYFATASA-DHTVKLWSLKSSFDFVPGTTRKVTTLKLEQTRQI 531 Query: 292 HFVQDVV---LSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQI 462 F DV+ +S DG+F + D ++++ L + GH+ VLS+ S D++ + Sbjct: 532 DFTDDVLAVKISPDGRFVAASLLDNTVKVYYLDSLKFFLNLYGHKLPVLSMDISYDSKLL 591 Query: 463 VSASRDRTIKLWN-TLGECKYTI 528 V+ S D+ +K+W G+C +I Sbjct: 592 VTCSADKNVKIWGLDFGDCHKSI 614 Score = 43.5 bits (101), Expect = 4e-04 Identities = 34/137 (24%), Positives = 61/137 (44%) Frame = +1 Query: 88 ESLVYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVP 267 +SL + + GH V ++ D S +V+ S DK++ +W L ++G Sbjct: 564 DSLKFFLNLYGHKLPVLSMDISYD-SKLLVTCSADKNVKIWGL------------DFGDC 610 Query: 268 FRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSI 447 + + H + +V D + S D E+R WD + + GH +V ++A + Sbjct: 611 HKSIFAHQDSIMEVTFQPDTYNFFTCSKDREVRYWDGKSFDLILKLRGHHSEVWALA--V 668 Query: 448 DNRQIVSASRDRTIKLW 498 +VS S D +I+LW Sbjct: 669 GPTFVVSGSHDHSIRLW 685 Score = 42.7 bits (99), Expect = 7e-04 Identities = 20/78 (25%), Positives = 37/78 (47%) Frame = +1 Query: 268 FRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSI 447 F L GH V + +S D + ++ S D +++W L G + H+ ++ V F Sbjct: 569 FLNLYGHKLPVLSMDISYDSKLLVTCSADKNVKIWGLDFGDCHKSIFAHQDSIMEVTFQP 628 Query: 448 DNRQIVSASRDRTIKLWN 501 D + S+DR ++ W+ Sbjct: 629 DTYNFFTCSKDREVRYWD 646 Score = 40.0 bits (92), Expect = 0.004 Identities = 34/144 (23%), Positives = 56/144 (38%), Gaps = 15/144 (10%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPI-------QATQDTSSEYGVPF 270 + GH VT + + + S S D ++VWD+ Q T + P Sbjct: 100 LNGHKSAVTTMDFDKMGTR-LASGSMDTDIIVWDIVAETGLFRLRGHKDQITKLLFITPP 158 Query: 271 RRLTGHGHFVQ--------DVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDV 426 + T V DV S F LS D ++LWDLS V H+ ++ Sbjct: 159 SKNTAEETVVDTDIDSGDMDVDSKSSDSFLLSVGKDSFMKLWDLSIQHCVETHVDHQGEI 218 Query: 427 LSVAFSIDNRQIVSASRDRTIKLW 498 ++ S D ++ ++A +K+W Sbjct: 219 WAMCVSPDAKRCLTAGTGSDVKVW 242 Score = 36.2 bits (82), Expect = 0.063 Identities = 15/49 (30%), Positives = 26/49 (53%) Frame = +1 Query: 355 GELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN 501 GEL ++D+++ R H+ + +A D +AS D T+KLW+ Sbjct: 457 GELEVYDIASSSLIERIQAHDGAIWDLAVGHDGTYFATASADHTVKLWS 505 Score = 29.6 bits (65), Expect = 5.9 Identities = 19/68 (27%), Positives = 32/68 (47%) Frame = +1 Query: 310 VLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTI 489 + + D +A+ G DG +RLW G GH+ V ++ F ++ S S D I Sbjct: 72 IANFDEMYAV-GYADGSIRLW--KDGELLITLNGHKSAVTTMDFDKMGTRLASGSMDTDI 128 Query: 490 KLWNTLGE 513 +W+ + E Sbjct: 129 IVWDIVAE 136
>PRP19_CHICK (Q5ZMA2) Pre-mRNA-splicing factor 19 (PRP19/PSO4 homolog)| Length = 505 Score = 51.2 bits (121), Expect = 2e-06 Identities = 33/131 (25%), Positives = 57/131 (43%) Frame = +1 Query: 109 VMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 V+R H VT ++ +++SSS D+ D+ T+ T G H Sbjct: 302 VVRAHEGSVTGLSLHATGD-YLLSSSDDQYWAFSDIQTGRVLTKVTDESSGCALTCAQFH 360 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVS 468 DG +G+ D ++++WDL F GH + S+AFS + + + Sbjct: 361 ----------PDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLAT 410 Query: 469 ASRDRTIKLWN 501 A+ D ++KLW+ Sbjct: 411 AADDSSVKLWD 421 Score = 37.0 bits (84), Expect = 0.037 Identities = 21/61 (34%), Positives = 30/61 (49%) Frame = +1 Query: 319 SDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLW 498 SD L+G D + ++D S+ GH K V SV F + SAS D TI++W Sbjct: 233 SDTNKILTGGADKNVIVFDKSSEQILATLKGHSKKVTSVVFHPSQDLVFSASPDATIRIW 292 Query: 499 N 501 + Sbjct: 293 S 293 Score = 33.5 bits (75), Expect = 0.41 Identities = 29/129 (22%), Positives = 55/129 (42%), Gaps = 1/129 (0%) Frame = +1 Query: 118 GHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHF 297 GH+ +T+IA +N ++ +++ D S+ +WDL F+ L +F Sbjct: 391 GHSGPITSIAFS-ENGYYLATAADDSSVKLWDLRKLKN------------FKTLQLDNNF 437 Query: 298 -VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSAS 474 V+ ++ G + G D ++ + T + F H VAF + I S Sbjct: 438 EVKSLIFDQSGTYLALGGTDVQIYICKQWTEIL--HFTEHSGLTTGVAFGHHAKFIASTG 495 Query: 475 RDRTIKLWN 501 DR++K ++ Sbjct: 496 MDRSLKFYS 504 Score = 32.3 bits (72), Expect = 0.92 Identities = 25/105 (23%), Positives = 43/105 (40%), Gaps = 1/105 (0%) Frame = +1 Query: 172 IVSSSRDKSLLVWDLTNP-IQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGS 348 I++ DK+++V+D ++ I AT L GH V VV S S Sbjct: 238 ILTGGADKNVIVFDKSSEQILAT-------------LKGHSKKVTSVVFHPSQDLVFSAS 284 Query: 349 WDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDR 483 D +R+W + + HE V ++ ++S+S D+ Sbjct: 285 PDATIRIWSVPNASCVQVVRAHEGSVTGLSLHATGDYLLSSSDDQ 329
>GBB_CRYPA (O14435) Guanine nucleotide-binding protein beta subunit| Length = 359 Score = 51.2 bits (121), Expect = 2e-06 Identities = 33/126 (26%), Positives = 55/126 (43%), Gaps = 1/126 (0%) Frame = +1 Query: 160 NSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFA- 336 N I++SS D + + WD+ E G H V + L+ Q Sbjct: 170 NDRSILTSSGDMTCMKWDI------------ETGTKQIEFADHLGDVMSISLNPTNQNTF 217 Query: 337 LSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNTLGEC 516 +SG+ D +LWD+ G + F GHE D+ ++ F D V+ S D T +L++ + Sbjct: 218 ISGACDAFAKLWDIRAGKAVQTFAGHESDINAIQFFPDGHSFVTGSDDATCRLFDIRADR 277 Query: 517 KYTIGG 534 + + G Sbjct: 278 ELNVYG 283 Score = 41.2 bits (95), Expect = 0.002 Identities = 20/67 (29%), Positives = 32/67 (47%) Frame = +1 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASR 477 + V S G+ +G D E ++WD++ G VGHE V + S D + + S Sbjct: 291 ITSVATSVSGRLLFAGYDDFECKVWDVTRGEKVGSLVGHENRVSCLGVSNDGISLCTGSW 350 Query: 478 DRTIKLW 498 D +K+W Sbjct: 351 DSLLKIW 357 Score = 35.0 bits (79), Expect = 0.14 Identities = 22/80 (27%), Positives = 36/80 (45%) Frame = +1 Query: 133 VTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVV 312 +T++AT + + + D VWD+T G L GH + V + Sbjct: 291 ITSVATSVSGR-LLFAGYDDFECKVWDVTR------------GEKVGSLVGHENRVSCLG 337 Query: 313 LSSDGQFALSGSWDGELRLW 372 +S+DG +GSWD L++W Sbjct: 338 VSNDGISLCTGSWDSLLKIW 357 Score = 30.4 bits (67), Expect = 3.5 Identities = 13/37 (35%), Positives = 22/37 (59%) Frame = +1 Query: 391 TTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN 501 T R GH + ++ +S D R +VSAS+D + +W+ Sbjct: 63 TKRTLKGHLAKIYAMHWSTDRRHLVSASQDGKLIIWD 99 Score = 29.6 bits (65), Expect = 5.9 Identities = 18/77 (23%), Positives = 32/77 (41%) Frame = +1 Query: 271 RRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSID 450 R L GH + + S+D + +S S DG+L +WD T V++ A++ Sbjct: 65 RTLKGHLAKIYAMHWSTDRRHLVSASQDGKLIIWDAYTTNKVHAIPLRSSWVMTCAYAPS 124 Query: 451 NRQIVSASRDRTIKLWN 501 + D ++N Sbjct: 125 GNYVACGGLDNICSIYN 141
>UTP13_YEAST (Q05946) U3 small nucleolar RNA-associated protein 13 (U3| snoRNA-associated protein 13) Length = 817 Score = 50.8 bits (120), Expect = 2e-06 Identities = 36/140 (25%), Positives = 63/140 (45%), Gaps = 2/140 (1%) Frame = +1 Query: 121 HNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTN-PIQATQDTSSEYGVPFRRLTGHGHF 297 H + A++ ++S F ++S DK+ +W+L N ++AT L H Sbjct: 490 HEKDINALSVSPNDSIF-ATASYDKTCKIWNLENGELEAT-------------LANHKRG 535 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASR 477 + DV + + S D +++W L T + GH V +F +Q++S Sbjct: 536 LWDVSFCQYDKLLATSSGDKTVKIWSLDTFSVMKTLEGHTNAVQRCSFINKQKQLISCGA 595 Query: 478 DRTIKLWN-TLGECKYTIGG 534 D IK+W+ + GEC T+ G Sbjct: 596 DGLIKIWDCSSGECLKTLDG 615 Score = 49.7 bits (117), Expect = 6e-06 Identities = 35/135 (25%), Positives = 65/135 (48%), Gaps = 7/135 (5%) Frame = +1 Query: 118 GHNDVVTAIATPIDNSP----FIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTG 285 GH+ VTA+ P S F++++S D ++ W + P A+ D + T Sbjct: 432 GHSAAVTAVGLPNIVSKGYPEFLLTASNDLTIKKWIIPKPT-ASMDVQI---IKVSEYTR 487 Query: 286 HGHFVQDVVLS---SDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNR 456 H H LS +D FA + S+D ++W+L G H++ + V+F ++ Sbjct: 488 HAHEKDINALSVSPNDSIFA-TASYDKTCKIWNLENGELEATLANHKRGLWDVSFCQYDK 546 Query: 457 QIVSASRDRTIKLWN 501 + ++S D+T+K+W+ Sbjct: 547 LLATSSGDKTVKIWS 561 Score = 45.8 bits (107), Expect = 8e-05 Identities = 31/114 (27%), Positives = 51/114 (44%) Frame = +1 Query: 172 IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSW 351 + +SS DK++ +W L DT S + L GH + VQ + + +S Sbjct: 548 LATSSGDKTVKIWSL--------DTFSV----MKTLEGHTNAVQRCSFINKQKQLISCGA 595 Query: 352 DGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNTLGE 513 DG +++WD S+G + GH + +++ D IVSA D + W E Sbjct: 596 DGLIKIWDCSSGECLKTLDGHNNRLWALSTMNDGDMIVSADADGVFQFWKDCTE 649
>WDR1_XENLA (Q9W7F2) WD-repeat protein 1 (Actin-interacting protein 1) (XAIP1)| Length = 608 Score = 50.8 bits (120), Expect = 2e-06 Identities = 33/103 (32%), Positives = 51/103 (49%), Gaps = 9/103 (8%) Frame = +1 Query: 259 GVPFR---RLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVG---HEK 420 G PF+ ++ H FV V S DG S DG++ L+D TG G H+ Sbjct: 176 GPPFKFKFTMSDHSRFVNCVRFSPDGSKLASAGADGQIFLYDGKTGEKVCSLGGSKAHDG 235 Query: 421 DVLSVAFSIDNRQIVSASRDRTIKLWNTLGECKYT---IGGDL 540 + +V++S D Q++SAS D+T K+W+ T +G D+ Sbjct: 236 GIYAVSWSPDGTQLLSASGDKTTKIWDVAANSAVTTFNLGSDV 278 Score = 37.4 bits (85), Expect = 0.028 Identities = 26/79 (32%), Positives = 41/79 (51%), Gaps = 3/79 (3%) Frame = +1 Query: 265 PFRRLTGHGHFVQDVVLS-SDGQFAL-SGSWDGELRLWDLSTGVT-TRRFVGHEKDVLSV 435 P R + GH +Q + ++ SDG+ + +GS DG + WD TG T GH V S+ Sbjct: 312 PLRVIKGHNKSIQCMTVNNSDGRSTIYTGSHDGHINYWDAETGENDTFTGKGHTNQVSSM 371 Query: 436 AFSIDNRQIVSASRDRTIK 492 N Q+++ S D T++ Sbjct: 372 DLDGCN-QLITCSMDDTLR 389 Score = 30.8 bits (68), Expect = 2.7 Identities = 33/145 (22%), Positives = 62/145 (42%), Gaps = 9/145 (6%) Frame = +1 Query: 97 VYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRR 276 V+A + + V +A + F+ ++ KS+++ ++ NP A D +E Sbjct: 8 VFASLPQMERGVAKILAGDPKGNNFLYTNG--KSVIIRNIDNP--AIADIYTE------- 56 Query: 277 LTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLS-----TGVTTRRFVGHEKDVLSVAF 441 H H + G + SG G+LR+WD + + F G KD +A+ Sbjct: 57 ---HAHQAVVARYAPSGFYIASGDTSGKLRIWDTTQKEHLLKYEYQPFAGKIKD---IAW 110 Query: 442 SIDNRQIVSASRDR----TIKLWNT 504 + D+++I R ++ LW+T Sbjct: 111 TEDSKRIAVVGEGREKFASVFLWDT 135 Score = 29.3 bits (64), Expect = 7.8 Identities = 17/59 (28%), Positives = 29/59 (49%), Gaps = 1/59 (1%) Frame = +1 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRR-FVGHEKDVLSVAFSIDNRQIVSA 471 V D+ S DG F + + ++ ++ G + + + GH LSVA+S DN S+ Sbjct: 492 VTDLAYSHDGAFLAVTDANKVVTVFSVADGYSEKNSYYGHHAKALSVAWSPDNEHFASS 550
>SPG16_HUMAN (Q8N0X2) Sperm-associated antigen 16 protein (PF20 protein homolog)| Length = 631 Score = 50.8 bits (120), Expect = 2e-06 Identities = 30/89 (33%), Positives = 44/89 (49%), Gaps = 3/89 (3%) Frame = +1 Query: 277 LTGHGH--FVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSID 450 LTG GH ++ D G + S D ++LWDL TG F GH + V S + Sbjct: 388 LTGFGHTDWLSDCCFHPSGDKLATSSGDTTVKLWDLCTGDCILTFEGHSRAVWSCTWHSC 447 Query: 451 NRQIVSASRDRTIKLWNTLGE-CKYTIGG 534 + S+S D+T K+W+ E C+ T+ G Sbjct: 448 GNFVASSSLDKTSKIWDVNSERCRCTLYG 476 Score = 46.6 bits (109), Expect = 5e-05 Identities = 30/124 (24%), Positives = 54/124 (43%), Gaps = 1/124 (0%) Frame = +1 Query: 172 IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSW 351 + +SS D ++ +WDL G GH V S G F S S Sbjct: 409 LATSSGDTTVKLWDLCT------------GDCILTFEGHSRAVWSCTWHSCGNFVASSSL 456 Query: 352 DGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNT-LGECKYTI 528 D ++WD+++ GH V S+ F + ++++S D+T+ +W+ G C+ ++ Sbjct: 457 DKTSKIWDVNSERCRCTLYGHTDSVNSIEFFPFSNTLLTSSADKTLSIWDARTGICEQSL 516 Query: 529 GGDL 540 G + Sbjct: 517 YGHM 520 Score = 44.3 bits (103), Expect = 2e-04 Identities = 37/159 (23%), Positives = 60/159 (37%), Gaps = 31/159 (19%) Frame = +1 Query: 118 GHNDVVTAIAT-PIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGH 294 GH D V +I P N+ +++SS DK+L +WD I + + GH Sbjct: 476 GHTDSVNSIEFFPFSNT--LLTSSADKTLSIWDARTGICEQSLYGHMHSINDAIFDPRGH 533 Query: 295 FV------------------------------QDVVLSSDGQFALSGSWDGELRLWDLST 384 + +V S G+ S +G + L DL + Sbjct: 534 MIASCDACGVTKLWDFRKLLPIVSIDIGPSPGNEVNFDSSGRVLAQASGNGVIHLLDLKS 593 Query: 385 GVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN 501 G + +GHE + +V FS D + S D T++ W+ Sbjct: 594 G-EIHKLMGHENEAHTVVFSHDGEILFSGGSDGTVRTWS 631 Score = 42.4 bits (98), Expect = 9e-04 Identities = 29/111 (26%), Positives = 43/111 (38%) Frame = +1 Query: 169 FIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGS 348 F+ SSS DK+ +WD+ + + + T L GH V + L+ S Sbjct: 450 FVASSSLDKTSKIWDVNS--ERCRCT----------LYGHTDSVNSIEFFPFSNTLLTSS 497 Query: 349 WDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN 501 D L +WD TG+ + GH + F I S KLW+ Sbjct: 498 ADKTLSIWDARTGICEQSLYGHMHSINDAIFDPRGHMIASCDACGVTKLWD 548
>CORO_YEAST (Q06440) Coronin-like protein| Length = 651 Score = 50.8 bits (120), Expect = 2e-06 Identities = 43/144 (29%), Positives = 66/144 (45%), Gaps = 13/144 (9%) Frame = +1 Query: 109 VMRGHNDVVTAIATPIDNSPF----IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPF-- 270 + RGH TA D PF I S S D + +WD+ + D E G P Sbjct: 76 LFRGH----TAQVLDTDFDPFNDHRIASGSDDSKIGIWDIPENYKF-HDHVDEDGEPIDI 130 Query: 271 ---RRLTGHGHFVQDVVLSSDGQFAL-SGSWDGELRLWDLSTG---VTTRRFVGHEKDVL 429 + LTGH V V+ + L S S D ++LW++ TG +T + H V Sbjct: 131 KPVKFLTGHARKVGHVLYHPVAENVLASSSGDYTVKLWNVETGKDMITLK----HPDMVT 186 Query: 430 SVAFSIDNRQIVSASRDRTIKLWN 501 S++FS D + + +RD+ +++WN Sbjct: 187 SMSFSYDGNYLATVARDKKLRVWN 210
>YP183_YEAST (Q08924) WD-repeat protein YPL183C| Length = 1013 Score = 50.8 bits (120), Expect = 2e-06 Identities = 35/145 (24%), Positives = 66/145 (45%), Gaps = 2/145 (1%) Frame = +1 Query: 79 GAQESLVYAGVMR--GHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSS 252 G + S++Y+G+++ G + V T + +++WDL + + Sbjct: 131 GGERSILYSGIIKVFGPDKVYVNAGTVMGG------------VIIWDLFSETK------- 171 Query: 253 EYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLS 432 L GH + V LS++G++ S S D +RLWDL TG H + + Sbjct: 172 -----IHNLLGHEGSIFYVNLSNNGRYVASCSDDRSIRLWDLETGKQLSVGWSHTARIWN 226 Query: 433 VAFSIDNRQIVSASRDRTIKLWNTL 507 + F ++ +++S S D T ++WN + Sbjct: 227 LMFFDNDSKLISVSEDCTCRVWNII 251
>APAF_BRARE (Q9I9H8) Apoptotic protease-activating factor 1 (Apaf-1)| Length = 1261 Score = 50.4 bits (119), Expect = 3e-06 Identities = 37/118 (31%), Positives = 56/118 (47%), Gaps = 2/118 (1%) Frame = +1 Query: 157 DNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVL--SSDGQ 330 D+ +++SS D ++ VW + E V L GH V+ L SS Sbjct: 1018 DDCEILITSSEDSTIRVWKWR---------TGECMV----LQGHMEPVRKFHLLSSSSSP 1064 Query: 331 FALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNT 504 S S+DG +++WDL+ G + V HE VLS S D R + S +RT K+W++ Sbjct: 1065 HLFSWSFDGTVKVWDLTRGQMLQDLVCHEGAVLSCDVSSDGRLFATTSANRTAKVWSS 1122 Score = 47.4 bits (111), Expect = 3e-05 Identities = 29/78 (37%), Positives = 38/78 (48%), Gaps = 2/78 (2%) Frame = +1 Query: 274 RLTGHGH--FVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSI 447 RL H H V S DG S LR++ ++G HE+DVL AFS Sbjct: 610 RLVMHPHQGAVYYACFSKDGSKIASCGASKALRVFKSTSGEKLLELQAHEEDVLCCAFSP 669 Query: 448 DNRQIVSASRDRTIKLWN 501 D+R I + + DR +KLWN Sbjct: 670 DDRHIATCASDRKVKLWN 687 Score = 46.6 bits (109), Expect = 5e-05 Identities = 38/134 (28%), Positives = 61/134 (45%), Gaps = 1/134 (0%) Frame = +1 Query: 109 VMRGHNDVVTAI-ATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTG 285 V++GH + V +SP + S S D ++ VWDLT Q QD L Sbjct: 1044 VLQGHMEPVRKFHLLSSSSSPHLFSWSFDGTVKVWDLTRG-QMLQD-----------LVC 1091 Query: 286 HGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIV 465 H V +SSDG+ + S + ++W ++ GH+ V S FS DN+++ Sbjct: 1092 HEGAVLSCDVSSDGRLFATTSANRTAKVWSSASWKMLFLLEGHKDCVRSCRFSWDNKRLA 1151 Query: 466 SASRDRTIKLWNTL 507 + + I+LW+ L Sbjct: 1152 TGDDNGEIRLWSML 1165 Score = 46.2 bits (108), Expect = 6e-05 Identities = 30/130 (23%), Positives = 62/130 (47%), Gaps = 1/130 (0%) Frame = +1 Query: 130 VVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDV 309 V T+ A + ++SS D +++ D +N +Q ++ + L+ ++ Sbjct: 916 VHTSSAVALKRDTDVLSSHSDATIIAPDSSNRLQVLSGSTGAVVLESEELSSR---IRCS 972 Query: 310 VLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTI 489 +S + F GS DG +++ ++ + + + GH K V F+ D ++++S D TI Sbjct: 973 CISRNAAFVALGSEDGTVQVIEVPSSKASVKLSGHTKTVHHCQFTDDCEILITSSEDSTI 1032 Query: 490 KLWN-TLGEC 516 ++W GEC Sbjct: 1033 RVWKWRTGEC 1042 Score = 34.3 bits (77), Expect = 0.24 Identities = 17/48 (35%), Positives = 25/48 (52%) Frame = +1 Query: 361 LRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNT 504 + LW+ + GH V V FS D ++S+S D+TI+LW T Sbjct: 866 VELWNFESSKKKAECSGHLSWVHCVQFSPDGSLLLSSSDDQTIRLWET 913 Score = 30.0 bits (66), Expect = 4.5 Identities = 24/74 (32%), Positives = 34/74 (45%), Gaps = 9/74 (12%) Frame = +1 Query: 280 TGHGHFVQDVVLSSDGQFALSGSWDGELRLWD-----LSTGVTTRR---FVGHEKDVLSV 435 +GH +V V S DG LS S D +RLW+ S+ V +R + D + Sbjct: 881 SGHLSWVHCVQFSPDGSLLLSSSDDQTIRLWETDRVHTSSAVALKRDTDVLSSHSDATII 940 Query: 436 AFSIDNR-QIVSAS 474 A NR Q++S S Sbjct: 941 APDSSNRLQVLSGS 954
>WDR1_CHICK (O93277) WD-repeat protein 1 (Actin-interacting protein 1) (AIP1)| Length = 609 Score = 50.4 bits (119), Expect = 3e-06 Identities = 36/138 (26%), Positives = 63/138 (45%), Gaps = 6/138 (4%) Frame = +1 Query: 106 GVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFR---R 276 G + GHN V+ ++ + + S D ++ G PF+ Sbjct: 142 GEITGHNKVINSVDIKQTRPYRLATGSDDNCAAFFE---------------GPPFKFKFT 186 Query: 277 LTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVG---HEKDVLSVAFSI 447 L+ H FV V S DG + S DG++ ++D TG G H+ + ++++S Sbjct: 187 LSDHTRFVNCVRFSPDGNRFATASADGQIFIYDGKTGEKVCALGGGKAHDGGIYAISWSP 246 Query: 448 DNRQIVSASRDRTIKLWN 501 D+ Q++SAS D+T K+W+ Sbjct: 247 DSSQLLSASGDKTAKIWD 264 Score = 39.3 bits (90), Expect = 0.007 Identities = 41/173 (23%), Positives = 69/173 (39%), Gaps = 35/173 (20%) Frame = +1 Query: 88 ESLVYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDL-TNPIQATQDTSSEY-- 258 E + G + H+ + AI+ D+S ++S+S DK+ +WD+ N + +T + S Sbjct: 224 EKVCALGGGKAHDGGIYAISWSPDSSQ-LLSASGDKTAKIWDVGANSVVSTFNMGSNVLD 282 Query: 259 -----------------------------GVPFRRLTGHGHFVQDVVLSSDG--QFALSG 345 P R + GH +Q + + +G + SG Sbjct: 283 QQLGCLWQKDHLLSLSLSGYINYLDKNNPDKPLRVIKGHSKSIQCLTVHKNGGKSYIYSG 342 Query: 346 SWDGELRLWDLSTGVTTR-RFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN 501 S DG + WD TG GH V +A + Q+V+ S D T++ N Sbjct: 343 SNDGHINYWDSDTGENDGFSGKGHTNQVSRMAVD-EMDQLVTCSMDDTVRYTN 394 Score = 32.0 bits (71), Expect = 1.2 Identities = 18/68 (26%), Positives = 29/68 (42%), Gaps = 1/68 (1%) Frame = +1 Query: 298 VQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRR-FVGHEKDVLSVAFSIDNRQIVSAS 474 V D+ S DG F + + ++ + G F GH V+ +A+S DN S Sbjct: 494 VTDLAYSHDGAFLAVCDANKVVTVFSVPDGYVEHNVFYGHHAKVVCIAWSPDNEHFASGG 553 Query: 475 RDRTIKLW 498 D + +W Sbjct: 554 MDMMVYVW 561
>DOA1_YEAST (P36037) Protein DOA1| Length = 715 Score = 50.4 bits (119), Expect = 3e-06 Identities = 41/146 (28%), Positives = 66/146 (45%), Gaps = 1/146 (0%) Frame = +1 Query: 67 TTMAGAQESLVYAGVMRGHN-DVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQD 243 T + SLVY ++ HN V A + F+ +S+ DK++ +W I+ Sbjct: 120 TAKVWKEGSLVYN--LQAHNASVWDAKVVSFSENKFLTASA-DKTIKLWQNDKVIKTFSG 176 Query: 244 TSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKD 423 H V+ + + DG F +S S DG ++L D+ TG R + GHE Sbjct: 177 I-------------HNDVVRHLAVVDDGHF-ISCSNDGLIKLVDMHTGDVLRTYEGHESF 222 Query: 424 VLSVAFSIDNRQIVSASRDRTIKLWN 501 V + + N IVS DRT+++W+ Sbjct: 223 VYCIKL-LPNGDIVSCGEDRTVRIWS 247 Score = 35.8 bits (81), Expect = 0.083 Identities = 38/164 (23%), Positives = 58/164 (35%), Gaps = 32/164 (19%) Frame = +1 Query: 103 AGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQAT-------------QD 243 + ++GH+ V + D+ + S SRD ++ +W + T D Sbjct: 6 SATLKGHDQDVRDVVAVDDSK--VASVSRDGTVRLWSKDDQWLGTVVYTGQGFLNSVCYD 63 Query: 244 TSSEY-----------GVPFRRLTGH-------GHFVQDVVLSSDGQFALSGSWDGELRL 369 + E GVP +G GH LS +SGSWD ++ Sbjct: 64 SEKELLLFGGKDTMINGVPLFATSGEDPLYTLIGHQGNVCSLSFQDGVVISGSWDKTAKV 123 Query: 370 WDLSTGVTTRRFVGHEKDVLSV-AFSIDNRQIVSASRDRTIKLW 498 W G H V S + ++AS D+TIKLW Sbjct: 124 W--KEGSLVYNLQAHNASVWDAKVVSFSENKFLTASADKTIKLW 165 Score = 34.3 bits (77), Expect = 0.24 Identities = 19/48 (39%), Positives = 29/48 (60%), Gaps = 4/48 (8%) Frame = +1 Query: 409 GHEKDVLSVAFSIDNRQIVSASRDRTIKLWNT----LGECKYTIGGDL 540 GH++DV V ++D+ ++ S SRD T++LW+ LG YT G L Sbjct: 11 GHDQDVRDVV-AVDDSKVASVSRDGTVRLWSKDDQWLGTVVYTGQGFL 57
>TBL3_HUMAN (Q12788) WD-repeat protein SAZD (Transducin beta-like 3 protein)| Length = 519 Score = 50.4 bits (119), Expect = 3e-06 Identities = 43/155 (27%), Positives = 72/155 (46%), Gaps = 18/155 (11%) Frame = +1 Query: 109 VMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 ++ GH D+V A+ S ++D+S+ +W + +A Q G +GH Sbjct: 257 ILHGHTDIVLALDV-FRKGWLFASCAKDQSVRIWRMN---KAGQVMCVAQG------SGH 306 Query: 289 GHFVQDVVLSS-DGQFALSGSWDGELRLWDLSTGV-----------------TTRRFVGH 414 H V V S F ++GS D ++LW L + TT+R H Sbjct: 307 THSVGTVCCSRLKESFLVTGSQDCTVKLWPLPKALLSKNTAPDNGPILLQAHTTQRC--H 364 Query: 415 EKDVLSVAFSIDNRQIVSASRDRTIKLWNTLGECK 519 +KD+ SVA + +++ + + S+DRT KLW L +C+ Sbjct: 365 DKDINSVAIAPNDKLLATGSQDRTAKLW-ALPQCQ 398 Score = 38.1 bits (87), Expect = 0.017 Identities = 41/158 (25%), Positives = 62/158 (39%), Gaps = 12/158 (7%) Frame = +1 Query: 115 RGHNDVVTAIATPIDNSPFIV-SSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 RG VV +A D + ++ SS+ D ++ VW L QD S LT H Sbjct: 34 RGSPGVVHLVAFHPDPTRLLLFSSATDAAIRVWSL-------QDRSC-----LAVLTAHY 81 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTR----------RFVGHEKDVLSVAF 441 V + S+DG LS D +WDL + TR + E+ V + Sbjct: 82 SAVTSLAFSADGHTMLSSGRDKICIIWDLQSCQATRTVPVFESVEAAVLLPEEPVSQLGV 141 Query: 442 SIDNRQIVSASRDRTIKLWNTL-GECKYTIGGDLGGGE 552 ++A T+++W G+C YT G G+ Sbjct: 142 KSPGLYFLTAGDQGTLRVWEAASGQCVYTQAQPPGPGQ 179 Score = 32.7 bits (73), Expect = 0.70 Identities = 18/56 (32%), Positives = 30/56 (53%), Gaps = 2/56 (3%) Frame = +1 Query: 340 SGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIV--SASRDRTIKLWN 501 +G DG +R+WD+ T F G V VAF D +++ S++ D I++W+ Sbjct: 12 TGGCDGAVRVWDIVRHYGTHHFRGSPGVVHLVAFHPDPTRLLLFSSATDAAIRVWS 67 Score = 29.3 bits (64), Expect = 7.8 Identities = 21/102 (20%), Positives = 39/102 (38%), Gaps = 3/102 (2%) Frame = +1 Query: 118 GHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTG---H 288 GH V + F+V+ S+D ++ +W L + + + + T H Sbjct: 305 GHTHSVGTVCCSRLKESFLVTGSQDCTVKLWPLPKALLSKNTAPDNGPILLQAHTTQRCH 364 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGH 414 + V ++ + + +GS D +LW L F GH Sbjct: 365 DKDINSVAIAPNDKLLATGSQDRTAKLWALPQCQLLGVFSGH 406
>SCON2_NEUCR (Q01277) Sulfur controller 2 (SCON2)| Length = 650 Score = 50.4 bits (119), Expect = 3e-06 Identities = 38/142 (26%), Positives = 67/142 (47%) Frame = +1 Query: 109 VMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 V++GH + VT + DN + + S D ++ +W++ T++ R L GH Sbjct: 289 VLKGHENGVTCLQLD-DN--ILATGSYDTTIKIWNIE-----TEEC-------IRTLVGH 333 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVS 468 ++ L D +SGS D +++W+ TG F H V+SV F D + S Sbjct: 334 TAGIR--ALQFDDSKLISGSLDHTIKVWNWHTGECLSTFAAHTDSVISVHF--DGHLLAS 389 Query: 469 ASRDRTIKLWNTLGECKYTIGG 534 S D+T+K+++ + Y + G Sbjct: 390 GSSDKTVKIFDFNSKETYCLKG 411 Score = 45.1 bits (105), Expect = 1e-04 Identities = 27/84 (32%), Positives = 41/84 (48%), Gaps = 1/84 (1%) Frame = +1 Query: 295 FVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSAS 474 FV D ++ ++G D +RLWD +TG R GH + V S+A D +++S + Sbjct: 538 FVADESRPLPPRYFMTGGLDSTMRLWDSATGRCLRTLFGHLEGVWSLAG--DTIRVISGA 595 Query: 475 RDRTIKLWN-TLGECKYTIGGDLG 543 D +K W G+C T G G Sbjct: 596 NDGMVKTWEPRSGKCDATYTGHCG 619 Score = 33.5 bits (75), Expect = 0.41 Identities = 29/109 (26%), Positives = 46/109 (42%) Frame = +1 Query: 169 FIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGS 348 + ++ D ++ +WD S G R L GH V L+ D +SG+ Sbjct: 550 YFMTGGLDSTMRLWD------------SATGRCLRTLFGHLEGVWS--LAGDTIRVISGA 595 Query: 349 WDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKL 495 DG ++ W+ +G + GH V V S + + S S D TI+L Sbjct: 596 NDGMVKTWEPRSGKCDATYTGHCGPVTCVGLS--DSLMASGSEDGTIRL 642 Score = 33.5 bits (75), Expect = 0.41 Identities = 34/147 (23%), Positives = 55/147 (37%), Gaps = 5/147 (3%) Frame = +1 Query: 55 SLRHTTMAGAQESLVYAGVMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQA 234 SL HT + H D V ++ + + S S DK++ ++D + Sbjct: 351 SLDHTIKVWNWHTGECLSTFAAHTDSVISVHF---DGHLLASGSSDKTVKIFDFNS---- 403 Query: 235 TQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGH 414 ++T L GH +V + + S S D ++LWDL T R + GH Sbjct: 404 -KETYC--------LKGHSDWVNSTHVDIKSRTVFSASDDTTIKLWDLDTRQVIRTYEGH 454 Query: 415 EKDVLSV-----AFSIDNRQIVSASRD 480 V V + D + AS+D Sbjct: 455 VGHVQQVLILPPEYEPDEEVLNGASQD 481
>UTP15_HUMAN (Q8TED0) U3 small nucleolar RNA-associated protein 15 homolog| Length = 518 Score = 50.4 bits (119), Expect = 3e-06 Identities = 24/60 (40%), Positives = 38/60 (63%) Frame = +1 Query: 322 DGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN 501 DG+ ++GS DG ++L+D+S R+F GH K V +V + D +VS + D T+KLW+ Sbjct: 91 DGRLLVAGSEDGGVQLFDISGRAPLRQFEGHTKAVHTVDSTADKYHVVSGADDYTVKLWD 150 Score = 35.4 bits (80), Expect = 0.11 Identities = 27/120 (22%), Positives = 51/120 (42%), Gaps = 1/120 (0%) Frame = +1 Query: 145 ATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSD 324 AT + +V+ S D + ++D++ P R+ GH V V ++D Sbjct: 86 ATFRQDGRLLVAGSEDGGVQLFDISGR------------APLRQFEGHTKAVHTVDSTAD 133 Query: 325 GQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDV-LSVAFSIDNRQIVSASRDRTIKLWN 501 +SG+ D ++LWD+ F H V A ++ ++ S D T+K+++ Sbjct: 134 KYHVVSGADDYTVKLWDIPNSKEILTFKEHSDYVRCGCASKLNPDLFITGSYDHTVKMFD 193 Score = 30.0 bits (66), Expect = 4.5 Identities = 21/81 (25%), Positives = 39/81 (48%) Frame = +1 Query: 277 LTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNR 456 L H V + LSS GQ LSGS D +++++ ++ F + +LS+A + ++ Sbjct: 244 LKNHHKTVTCLCLSSSGQRLLSGSLDRKVKVYSTTSYKVVHSF-DYAASILSLALAHEDE 302 Query: 457 QIVSASRDRTIKLWNTLGECK 519 IV + + + + E K Sbjct: 303 TIVVGMTNGILSVKHRKSEAK 323
>PRP46_ASPFU (Q4WT34) Pre-mRNA-splicing factor prp46 (Pre-mRNA-processing| protein 46) Length = 453 Score = 50.1 bits (118), Expect = 4e-06 Identities = 35/131 (26%), Positives = 54/131 (41%), Gaps = 1/131 (0%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDL-TNPIQATQDTSSEYGVPFRRLTGH 288 + GH V +A P++ S DK + WDL TN + R GH Sbjct: 182 LTGHISTVRGLAVS-PRHPYLFSCGEDKMVKCWDLETNKV-------------IRHYHGH 227 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVS 468 V + L ++G DG R+WD+ T GH+ V + + QI++ Sbjct: 228 LSGVYTLALHPRLDLLVTGGRDGVARVWDMRTRSNIHVLSGHKGTVADLKCQEADPQIIT 287 Query: 469 ASRDRTIKLWN 501 S D T++LW+ Sbjct: 288 GSLDATVRLWD 298 Score = 45.8 bits (107), Expect = 8e-05 Identities = 23/93 (24%), Positives = 48/93 (51%), Gaps = 3/93 (3%) Frame = +1 Query: 232 ATQDTSSEYGVPF---RRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRR 402 AT+ ++ P+ R ++GH +V+ + + + ++ SG+ D +++W+L+TG Sbjct: 122 ATRQQRPDWHPPWKLMRVISGHLGWVRSLAVEPNNEWFASGAGDRTIKIWNLATGALRLT 181 Query: 403 FVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN 501 GH V +A S + + S D+ +K W+ Sbjct: 182 LTGHISTVRGLAVSPRHPYLFSCGEDKMVKCWD 214 Score = 42.0 bits (97), Expect = 0.001 Identities = 34/109 (31%), Positives = 47/109 (43%) Frame = +1 Query: 172 IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSW 351 +V+ RD VWD+ T S V L+GH V D+ ++GS Sbjct: 243 LVTGGRDGVARVWDMR--------TRSNIHV----LSGHKGTVADLKCQEADPQIITGSL 290 Query: 352 DGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLW 498 D +RLWDL+ G T H+K V ++A SAS +IK W Sbjct: 291 DATVRLWDLAAGKTMGVLTHHKKGVRNLAIHPREFTFASASTG-SIKQW 338 Score = 35.4 bits (80), Expect = 0.11 Identities = 32/167 (19%), Positives = 62/167 (37%), Gaps = 37/167 (22%) Frame = +1 Query: 109 VMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLT--------------------NPI 228 V+ GH V + + P I++ S D ++ +WDL +P Sbjct: 265 VLSGHKGTVADLKCQ-EADPQIITGSLDATVRLWDLAAGKTMGVLTHHKKGVRNLAIHPR 323 Query: 229 QATQDTSSEYGVP---------FRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLS 381 + T ++S + + GH + + ++ D SG +G + WD Sbjct: 324 EFTFASASTGSIKQWKCPEGDFMQNFEGHNAVINSLAVNEDNVL-FSGGDNGSMCFWDWK 382 Query: 382 TGVTTRRF--------VGHEKDVLSVAFSIDNRQIVSASRDRTIKLW 498 TG + + E ++S F ++++ D+TIK+W Sbjct: 383 TGYKFQSIDTMAQPGSLDAEAGIMSATFDRTGLRLITGEADKTIKVW 429
>PRP46_EMENI (Q5BE22) Pre-mRNA-splicing factor prp46 (Pre-mRNA-processing| protein 46) Length = 452 Score = 50.1 bits (118), Expect = 4e-06 Identities = 35/131 (26%), Positives = 53/131 (40%), Gaps = 1/131 (0%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDL-TNPIQATQDTSSEYGVPFRRLTGH 288 + GH V +A P++ S DK + WDL TN + R GH Sbjct: 181 LTGHISTVRGLAVS-PRHPYLFSCGEDKMVKCWDLETNKV-------------IRHYHGH 226 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVS 468 V + L ++G DG R+WD+ T GH V V + Q+++ Sbjct: 227 LSGVYTLALHPRLDLLVTGGRDGVARVWDMRTRSNIHVLSGHTGTVADVQCQEADPQVIT 286 Query: 469 ASRDRTIKLWN 501 S D T++LW+ Sbjct: 287 GSLDATVRLWD 297 Score = 47.8 bits (112), Expect = 2e-05 Identities = 24/93 (25%), Positives = 48/93 (51%), Gaps = 3/93 (3%) Frame = +1 Query: 232 ATQDTSSEYGVPF---RRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRR 402 AT+ E+ P+ R ++GH +V+ + + + ++ SG+ D +++W+L+TG Sbjct: 121 ATRQQPPEWHAPWKLMRVISGHLGWVRSLAVEPNNEWFASGAGDRTIKIWNLATGALRLT 180 Query: 403 FVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWN 501 GH V +A S + + S D+ +K W+ Sbjct: 181 LTGHISTVRGLAVSPRHPYLFSCGEDKMVKCWD 213 Score = 44.3 bits (103), Expect = 2e-04 Identities = 36/113 (31%), Positives = 48/113 (42%) Frame = +1 Query: 172 IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSW 351 +V+ RD VWD+ T S V L+GH V DV ++GS Sbjct: 242 LVTGGRDGVARVWDMR--------TRSNIHV----LSGHTGTVADVQCQEADPQVITGSL 289 Query: 352 DGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNTLG 510 D +RLWDL+ G T H+K + S+A SAS +IK W G Sbjct: 290 DATVRLWDLAAGKTMGVLTHHKKGIRSLATHPREFTFASASTG-SIKQWKCPG 341 Score = 35.4 bits (80), Expect = 0.11 Identities = 33/167 (19%), Positives = 64/167 (38%), Gaps = 37/167 (22%) Frame = +1 Query: 109 VMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDL--------------------TNPI 228 V+ GH V + + P +++ S D ++ +WDL T+P Sbjct: 264 VLSGHTGTVADVQCQ-EADPQVITGSLDATVRLWDLAAGKTMGVLTHHKKGIRSLATHPR 322 Query: 229 QATQDTSSEYGVP---------FRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLS 381 + T ++S + + GH + + ++ D SG +G + WD Sbjct: 323 EFTFASASTGSIKQWKCPGGEFMQNFEGHNAIINTLSVNEDNVL-FSGGDNGSMSFWDWK 381 Query: 382 TG-----VTTRRFVGH---EKDVLSVAFSIDNRQIVSASRDRTIKLW 498 TG + T G E +++ F ++++ D+TIK+W Sbjct: 382 TGYRYQTIDTTAQPGSLEAEAGIMTSTFDRTGLRLITGEADKTIKVW 428
>PRL1_ARATH (Q42384) PP1/PP2A phosphatases pleiotropic regulator PRL1| Length = 486 Score = 50.1 bits (118), Expect = 4e-06 Identities = 36/130 (27%), Positives = 54/130 (41%) Frame = +1 Query: 112 MRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHG 291 + GH + V +A + ++ S+ DK + WDL E R GH Sbjct: 214 LTGHIEQVRGLAVS-NRHTYMFSAGDDKQVKCWDL------------EQNKVIRSYHGHL 260 Query: 292 HFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSA 471 V + L L+G D R+WD+ T + GH+ V SV + Q+V+ Sbjct: 261 SGVYCLALHPTLDVLLTGGRDSVCRVWDIRTKMQIFALSGHDNTVCSVFTRPTDPQVVTG 320 Query: 472 SRDRTIKLWN 501 S D TIK W+ Sbjct: 321 SHDTTIKFWD 330 Score = 49.7 bits (117), Expect = 6e-06 Identities = 23/78 (29%), Positives = 42/78 (53%) Frame = +1 Query: 268 FRRLTGHGHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSI 447 +R + GH +V+ V ++ +GS D +++WD++TGV GH + V +A S Sbjct: 169 YRVIQGHLGWVRSVAFDPSNEWFCTGSADRTIKIWDVATGVLKLTLTGHIEQVRGLAVSN 228 Query: 448 DNRQIVSASRDRTIKLWN 501 + + SA D+ +K W+ Sbjct: 229 RHTYMFSAGDDKQVKCWD 246 Score = 47.8 bits (112), Expect = 2e-05 Identities = 32/131 (24%), Positives = 58/131 (44%) Frame = +1 Query: 109 VMRGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGH 288 V++GH V ++A N F S+ D+++ +WD+ GV LTGH Sbjct: 171 VIQGHLGWVRSVAFDPSNEWFCTGSA-DRTIKIWDVAT------------GVLKLTLTGH 217 Query: 289 GHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVS 468 V+ + +S+ + S D +++ WDL R + GH V +A +++ Sbjct: 218 IEQVRGLAVSNRHTYMFSAGDDKQVKCWDLEQNKVIRSYHGHLSGVYCLALHPTLDVLLT 277 Query: 469 ASRDRTIKLWN 501 RD ++W+ Sbjct: 278 GGRDSVCRVWD 288 Score = 42.7 bits (99), Expect = 7e-04 Identities = 30/114 (26%), Positives = 44/114 (38%) Frame = +1 Query: 172 IVSSSRDKSLLVWDLTNPIQATQDTSSEYGVPFRRLTGHGHFVQDVVLSSDGQFALSGSW 351 +++ RD VWD+ +Q L+GH + V V ++GS Sbjct: 275 LLTGGRDSVCRVWDIRTKMQIFA------------LSGHDNTVCSVFTRPTDPQVVTGSH 322 Query: 352 DGELRLWDLSTGVTTRRFVGHEKDVLSVAFSIDNRQIVSASRDRTIKLWNTLGE 513 D ++ WDL G T H+K V ++ SAS D T K GE Sbjct: 323 DTTIKFWDLRYGKTMSTLTHHKKSVRAMTLHPKENAFASASADNTKKFSLPKGE 376 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 57,096,163 Number of Sequences: 219361 Number of extensions: 991286 Number of successful extensions: 8428 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 5019 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 7121 length of database: 80,573,946 effective HSP length: 105 effective length of database: 57,541,041 effective search space used: 4488201198 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
