Clone Name | bart42a04 |
---|---|
Clone Library Name | barley_pub |
>CYPH_MAIZE (P21569) Peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8) (PPIase)| (Rotamase) (Cyclophilin) (Cyclosporin A-binding protein) Length = 172 Score = 264 bits (674), Expect = 2e-70 Identities = 128/167 (76%), Positives = 138/167 (82%) Frame = +2 Query: 104 MANPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSF 283 MANP+VFFDMTVGGAPAGRIVMELY + VP+T ENFRALCTGEKGVGKSGKPLHYKGS+F Sbjct: 1 MANPRVFFDMTVGGAPAGRIVMELYANEVPKTAENFRALCTGEKGVGKSGKPLHYKGSTF 60 Query: 284 HRVIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFF 463 HRVIP+FMCQ ESIYGEKF DEKFV K PG+LSMANAGPNTNGSQFF Sbjct: 61 HRVIPEFMCQGGDFTRGNGTGGESIYGEKFPDEKFVRKQPAPGVLSMANAGPNTNGSQFF 120 Query: 464 ICTVPCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRSGICFKQVVIAD 604 ICTV WLDGKHVVFG+VVEGMDVVK IEKVG+R+G K V +AD Sbjct: 121 ICTVATPWLDGKHVVFGQVVEGMDVVKAIEKVGTRNGSTSKVVKVAD 167
>CYPH_LYCES (P21568) Peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8) (PPIase)| (Rotamase) (Cyclophilin) (Cyclosporin A-binding protein) Length = 171 Score = 258 bits (658), Expect = 1e-68 Identities = 123/167 (73%), Positives = 132/167 (79%) Frame = +2 Query: 104 MANPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSF 283 MANPKVFFD+T+GGAPAGR+VMEL+ D P+T ENFRALCTGEKGVGK GKPLHYKGS+F Sbjct: 1 MANPKVFFDLTIGGAPAGRVVMELFADTTPKTAENFRALCTGEKGVGKMGKPLHYKGSTF 60 Query: 284 HRVIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFF 463 HRVIP FMCQ ESIYG KF DE FV KHT PGILSMANAGP TNGSQFF Sbjct: 61 HRVIPGFMCQGGDFTAGNGTGGESIYGAKFNDENFVKKHTGPGILSMANAGPGTNGSQFF 120 Query: 464 ICTVPCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRSGICFKQVVIAD 604 ICT WL+GKHVVFG+VVEGMDV+K E VGS SG C K VVIAD Sbjct: 121 ICTAKTEWLNGKHVVFGQVVEGMDVIKKAEAVGSSSGRCSKPVVIAD 167
>CYPH_CATRO (Q39613) Peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8) (PPIase)| (Rotamase) (Cyclophilin) (Cyclosporin A-binding protein) Length = 172 Score = 256 bits (655), Expect = 3e-68 Identities = 124/167 (74%), Positives = 132/167 (79%) Frame = +2 Query: 104 MANPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSF 283 M NP+VFFDM+VGG PAGRIVMEL+ D PRT ENFRALCTGEKG G+SGKPLHYK SSF Sbjct: 1 MPNPRVFFDMSVGGQPAGRIVMELFADTTPRTAENFRALCTGEKGTGRSGKPLHYKDSSF 60 Query: 284 HRVIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFF 463 HRVIP FMCQ ESIYG KFADE F+ KHT PGILSMANAGPNTNGSQFF Sbjct: 61 HRVIPGFMCQGGDFTAGNGTGGESIYGAKFADENFIKKHTGPGILSMANAGPNTNGSQFF 120 Query: 464 ICTVPCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRSGICFKQVVIAD 604 ICT WLDGKHVVFG+VVEGMDVVK IEKVGS SG K+VV+ D Sbjct: 121 ICTAKTEWLDGKHVVFGQVVEGMDVVKAIEKVGSSSGRTAKKVVVED 167
>CP19B_ARATH (Q9SKQ0) Peptidyl-prolyl cis-trans isomerase CYP19-2 (EC 5.2.1.8)| (PPIase CYP19-2) (Rotamase cyclophilin-6) (Cyclophilin of 19 kDa 2) (Cyclophilin-2) Length = 174 Score = 254 bits (649), Expect = 1e-67 Identities = 123/166 (74%), Positives = 135/166 (81%) Frame = +2 Query: 107 ANPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFH 286 ++PKVFFDMT+GGAPAG+IVMELY D P+T ENFRALCTGEKGVG+SGKPLH+KGSSFH Sbjct: 3 SHPKVFFDMTIGGAPAGKIVMELYTDKTPKTAENFRALCTGEKGVGRSGKPLHFKGSSFH 62 Query: 287 RVIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFFI 466 RVIP+FMCQ ESIYG KF DE F KHT PGILSMANAG NTNGSQFFI Sbjct: 63 RVIPNFMCQGGDFTKGNGTGGESIYGAKFEDENFERKHTGPGILSMANAGANTNGSQFFI 122 Query: 467 CTVPCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRSGICFKQVVIAD 604 CTV +WLDGKHVVFG+VVEG+DVVK IEK+GS SG K VVIAD Sbjct: 123 CTVKTDWLDGKHVVFGQVVEGLDVVKAIEKIGSSSGKPTKPVVIAD 168
>CYPH_LUPLU (O49886) Peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8) (PPIase)| (Rotamase) (Cyclophilin) (Cyclosporin A-binding protein) Length = 172 Score = 249 bits (636), Expect = 4e-66 Identities = 119/167 (71%), Positives = 132/167 (79%) Frame = +2 Query: 104 MANPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSF 283 M+NPKVFFDM + G PAGRIVMELY D PRT ENFRALCTGEKGVG+SGKPLHYKGS+F Sbjct: 1 MSNPKVFFDMAIAGNPAGRIVMELYADTTPRTAENFRALCTGEKGVGRSGKPLHYKGSTF 60 Query: 284 HRVIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFF 463 HRVIP+FMCQ ESIYG KFADE F+ +HT PGILSMANAG TNGSQFF Sbjct: 61 HRVIPNFMCQGGDFTAGNGTGAESIYGAKFADENFIKRHTGPGILSMANAGAGTNGSQFF 120 Query: 464 ICTVPCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRSGICFKQVVIAD 604 ICT WLDGKHVVFG+V+EGM+VV++IEKVGS SG + V IAD Sbjct: 121 ICTEKTEWLDGKHVVFGKVIEGMNVVRDIEKVGSGSGKTSRPVTIAD 167
>CP18C_ARATH (P34790) Peptidyl-prolyl cis-trans isomerase CYP18-3 (EC 5.2.1.8)| (PPIase CYP18-3) (Rotamase cyclophilin-1) (Cyclophilin of 18 kDa 3) (Cyclosporin A-binding protein) Length = 172 Score = 249 bits (635), Expect = 6e-66 Identities = 122/167 (73%), Positives = 131/167 (78%) Frame = +2 Query: 104 MANPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSF 283 MA PKV+FDMT+ G PAGRIVMELY D PRT ENFRALCTGEKGVG +GKPLH+KGS F Sbjct: 1 MAFPKVYFDMTIDGQPAGRIVMELYTDKTPRTAENFRALCTGEKGVGGTGKPLHFKGSKF 60 Query: 284 HRVIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFF 463 HRVIP+FMCQ ESIYG KF DE F KHT PGILSMANAG NTNGSQFF Sbjct: 61 HRVIPNFMCQGGDFTAGNGTGGESIYGSKFEDENFERKHTGPGILSMANAGANTNGSQFF 120 Query: 464 ICTVPCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRSGICFKQVVIAD 604 ICTV +WLDGKHVVFG+VVEG+DVVK IEKVGS SG K VV+AD Sbjct: 121 ICTVKTDWLDGKHVVFGQVVEGLDVVKAIEKVGSSSGKPTKPVVVAD 167
>CP19A_ARATH (Q38900) Peptidyl-prolyl cis-trans isomerase CYP19-1 (EC 5.2.1.8)| (PPIase CYP19-1) (Rotamase cyclophilin-3) (Cyclophilin of 19 kDa 1) Length = 173 Score = 248 bits (634), Expect = 7e-66 Identities = 120/165 (72%), Positives = 130/165 (78%) Frame = +2 Query: 110 NPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHR 289 NPKV+FDMTVGG AGRIVMELY D P T ENFRALCTGE+G+GK GKPLHYKGSSFHR Sbjct: 4 NPKVYFDMTVGGKSAGRIVMELYADTTPETAENFRALCTGERGIGKQGKPLHYKGSSFHR 63 Query: 290 VIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFFIC 469 VIP FMCQ ESIYG KF DE F+ KHT PGILSMANAG NTNGSQFFIC Sbjct: 64 VIPKFMCQGGDFTAGNGTGGESIYGSKFKDENFIKKHTGPGILSMANAGANTNGSQFFIC 123 Query: 470 TVPCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRSGICFKQVVIAD 604 T +WLDGKHVVFG+VVEG++VV++IEKVGS SG K VVIAD Sbjct: 124 TEKTSWLDGKHVVFGQVVEGLNVVRDIEKVGSDSGRTSKPVVIAD 168
>CYPH_BRANA (P24525) Peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8) (PPIase)| (Rotamase) (Cyclophilin) (Cyclosporin A-binding protein) Length = 171 Score = 248 bits (632), Expect = 1e-65 Identities = 121/167 (72%), Positives = 130/167 (77%) Frame = +2 Query: 104 MANPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSF 283 M NPKV+FDMTVG AGRIVMELY D VP T ENFRALCTGE+G+GKSGKPLHYKGS+F Sbjct: 1 MVNPKVYFDMTVGDKAAGRIVMELYADTVPETAENFRALCTGERGIGKSGKPLHYKGSAF 60 Query: 284 HRVIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFF 463 HRVIP FMCQ ESIYG KF DE FV KHT PGILSM NAG NTNGSQFF Sbjct: 61 HRVIPKFMCQGGDFTAGNGTGGESIYGMKFKDENFVKKHTGPGILSMRNAGSNTNGSQFF 120 Query: 464 ICTVPCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRSGICFKQVVIAD 604 ICT +WLDGKHVVFG+VVEGMDVV++IEKVGS SG K+VV D Sbjct: 121 ICTEKTSWLDGKHVVFGQVVEGMDVVRDIEKVGSDSGRTSKKVVTCD 167
>CYP7_CAEEL (P52015) Peptidyl-prolyl cis-trans isomerase 7 (EC 5.2.1.8)| (PPIase) (Rotamase) (Cyclophilin-7) Length = 171 Score = 238 bits (607), Expect = 1e-62 Identities = 112/167 (67%), Positives = 127/167 (76%) Frame = +2 Query: 104 MANPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSF 283 M+ P+VFFD+T+ G P GRIVMELY D VP+T ENFRALCTGEKGVGKSGKPLH+KGS F Sbjct: 1 MSRPRVFFDITIAGKPTGRIVMELYNDIVPKTAENFRALCTGEKGVGKSGKPLHFKGSKF 60 Query: 284 HRVIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFF 463 HR+IP+FM Q ESIYGEKF DE F KHT PG+LSMANAGPNTNGSQFF Sbjct: 61 HRIIPEFMIQGGDFTRGNGTGGESIYGEKFPDENFKEKHTGPGVLSMANAGPNTNGSQFF 120 Query: 464 ICTVPCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRSGICFKQVVIAD 604 +CTV WLDGKHVVFG VVEG+D+V +E GS SG + +IAD Sbjct: 121 LCTVKTAWLDGKHVVFGRVVEGLDIVSKVEGNGSSSGTPKSECLIAD 167
>CYP3_CAEEL (P52011) Peptidyl-prolyl cis-trans isomerase 3 (EC 5.2.1.8)| (PPIase) (Rotamase) (Cyclophilin-3) Length = 173 Score = 235 bits (600), Expect = 7e-62 Identities = 112/167 (67%), Positives = 127/167 (76%) Frame = +2 Query: 104 MANPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSF 283 M+ KVFFD+T+GG +GRIVMELY D VP+T NFRALCTGE G+GKSGKPLH+KGS F Sbjct: 1 MSRSKVFFDITIGGKASGRIVMELYDDVVPKTAGNFRALCTGENGIGKSGKPLHFKGSKF 60 Query: 284 HRVIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFF 463 HR+IP+FM Q ESIYGEKF DE F KHT PG+LSMANAGPNTNGSQFF Sbjct: 61 HRIIPNFMIQGGDFTRGNGTGGESIYGEKFPDENFKEKHTGPGVLSMANAGPNTNGSQFF 120 Query: 464 ICTVPCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRSGICFKQVVIAD 604 +CTV WLDGKHVVFG VVEG+DVVK +E GS+SG K +IAD Sbjct: 121 LCTVKTEWLDGKHVVFGRVVEGLDVVKAVESNGSQSGKPVKDCMIAD 167
>CP18D_ARATH (Q42406) Peptidyl-prolyl cis-trans isomerase CYP18-4 (EC 5.2.1.8)| (PPIase CYP18-4) (Rotamase cyclophilin-5) (Cyclophilin of 18 kDa 4) (Cyclophilin-1) Length = 172 Score = 234 bits (597), Expect = 1e-61 Identities = 113/167 (67%), Positives = 126/167 (75%) Frame = +2 Query: 104 MANPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSF 283 M+NP+VFFDM++ G P GRI MEL+ D P T ENFRALCTGEKG+GK GKPLH+KGS F Sbjct: 1 MSNPRVFFDMSLSGTPIGRIEMELFADTTPNTAENFRALCTGEKGMGKLGKPLHFKGSIF 60 Query: 284 HRVIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFF 463 HRVIP FMCQ ESIYG KF DE F+ KHT GILSMAN+GPNTNGSQFF Sbjct: 61 HRVIPGFMCQGGDFTAKNGTGGESIYGAKFKDENFIKKHTGAGILSMANSGPNTNGSQFF 120 Query: 464 ICTVPCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRSGICFKQVVIAD 604 ICT +WLDGKHVVFG+VV+G+DVVK IEKVGS SG K V I D Sbjct: 121 ICTDKTSWLDGKHVVFGQVVKGLDVVKAIEKVGSDSGKTSKVVTITD 167
>PPI2_SYNY3 (P73789) Peptidyl-prolyl cis-trans isomerase slr1251 (EC 5.2.1.8)| (PPIase) (Rotamase) Length = 171 Score = 226 bits (577), Expect = 3e-59 Identities = 107/163 (65%), Positives = 127/163 (77%) Frame = +2 Query: 116 KVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVI 295 KVFFD+T+G AGRIVMEL+ + P+T ENFRALCTGEKGVGK+GKPLH+KGS FHRVI Sbjct: 4 KVFFDITIGSDTAGRIVMELFDEVTPKTAENFRALCTGEKGVGKAGKPLHFKGSHFHRVI 63 Query: 296 PDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFFICTV 475 DFM Q ESIYGEKFADE F KH +PG+LSMANAGPNTNGSQFF+ V Sbjct: 64 TDFMAQGGDFTRGNGTGGESIYGEKFADENFQLKHDRPGLLSMANAGPNTNGSQFFLTFV 123 Query: 476 PCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRSGICFKQVVIAD 604 PC WLDGKHVVFGEVVEG+++++ +E GS+SG + +VI+D Sbjct: 124 PCPWLDGKHVVFGEVVEGLEILEQLEANGSQSGQTKQAIVISD 166
>CYP1_CAEEL (P52009) Peptidyl-prolyl cis-trans isomerase 1 (EC 5.2.1.8)| (PPIase) (Rotamase) (Cyclophilin-1) Length = 192 Score = 226 bits (576), Expect = 4e-59 Identities = 109/164 (66%), Positives = 122/164 (74%) Frame = +2 Query: 113 PKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRV 292 PKVFFD+++G PAGR+ MEL+ D VP+T ENFRALCTGEKGVG+ G LH+KGS FHR+ Sbjct: 22 PKVFFDVSIGEEPAGRVTMELFNDVVPKTAENFRALCTGEKGVGEQGVALHFKGSKFHRI 81 Query: 293 IPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFFICT 472 IP+FM Q ESIYG KF DE F KHT PG LSMANAGPNTNGSQFFICT Sbjct: 82 IPEFMIQGGDFTRHNGTGGESIYGNKFKDENFDLKHTGPGCLSMANAGPNTNGSQFFICT 141 Query: 473 VPCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRSGICFKQVVIAD 604 V WLDG HVVFG+V +GM VVK IEK+GSRSG K V IAD Sbjct: 142 VDTPWLDGGHVVFGQVTDGMSVVKKIEKMGSRSGAPAKTVTIAD 185
>CP19C_ARATH (Q38867) Peptidyl-prolyl cis-trans isomerase CYP19-3 (EC 5.2.1.8)| (PPIase CYP19-3) (Rotamase cyclophilin-2) (Cyclophilin of 19 kDa 3) (Cyclophilin-4) Length = 176 Score = 226 bits (576), Expect = 4e-59 Identities = 109/167 (65%), Positives = 125/167 (74%) Frame = +2 Query: 104 MANPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSF 283 MANPKVFFD+ +G AGR+VMEL+ D PRT NFRALCTGE G+GK+GK LHYKGS+F Sbjct: 1 MANPKVFFDILIGKMKAGRVVMELFADVTPRTANNFRALCTGENGIGKAGKALHYKGSAF 60 Query: 284 HRVIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFF 463 HR+IP FMCQ ESIYG KF DE F KHT PGILSMAN+GPNTNGSQFF Sbjct: 61 HRIIPGFMCQGGDFTRGNGTGGESIYGSKFEDENFKLKHTGPGILSMANSGPNTNGSQFF 120 Query: 464 ICTVPCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRSGICFKQVVIAD 604 ICT +WLDGKHVVFG+VV+G +VVK +E VGS G ++VVI D Sbjct: 121 ICTEKTSWLDGKHVVFGKVVDGYNVVKAMEDVGSDMGNPSERVVIED 167
>CYP2_CAEEL (P52010) Peptidyl-prolyl cis-trans isomerase 2 (EC 5.2.1.8)| (PPIase) (Rotamase) (Cyclophilin-2) Length = 172 Score = 226 bits (575), Expect = 5e-59 Identities = 110/167 (65%), Positives = 121/167 (72%) Frame = +2 Query: 104 MANPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSF 283 M KVFFD+T+GG GRIVMELY D VP+T ENFRALCTGEKG GKSGK LH+KGS F Sbjct: 1 MPRVKVFFDITIGGKKGGRIVMELYNDIVPKTAENFRALCTGEKGKGKSGKKLHFKGSKF 60 Query: 284 HRVIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFF 463 HR+IP+FM Q ESI+GEKF DE F KHT PG+LSMAN G NTNGSQFF Sbjct: 61 HRIIPEFMIQGGDFTEGNGTGGESIHGEKFDDENFKEKHTGPGVLSMANCGANTNGSQFF 120 Query: 464 ICTVPCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRSGICFKQVVIAD 604 +CTV WLDGKHVVFG+V+EGMDVVK IE GS G VIAD Sbjct: 121 LCTVKTTWLDGKHVVFGKVIEGMDVVKAIESKGSEDGAPSAPCVIAD 167
>CP19D_ARATH (Q8LDP4) Peptidyl-prolyl cis-trans isomerase CYP19-4 precursor (EC| 5.2.1.8) (PPIase CYP19-4) (Rotamase CYP19-4) (Cyclophilin of 19 kDa 4) (Cyclophilin-5) Length = 201 Score = 215 bits (547), Expect = 9e-56 Identities = 105/163 (64%), Positives = 123/163 (75%) Frame = +2 Query: 116 KVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVI 295 KV+FD+ + G AGR+V+ L+ AVP+T ENFRALCTGEKGVGKSGKPLHYKGS FHR+I Sbjct: 33 KVYFDVEIDGKSAGRVVIGLFGKAVPKTAENFRALCTGEKGVGKSGKPLHYKGSKFHRII 92 Query: 296 PDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFFICTV 475 P FM Q ESIYG+KFADE F KHT PG+LSMAN+G +TNGSQFFI TV Sbjct: 93 PSFMIQGGDFTHGNGMGGESIYGQKFADENFKLKHTGPGVLSMANSGEDTNGSQFFITTV 152 Query: 476 PCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRSGICFKQVVIAD 604 +WLDG+HVVFG+VV+GMDVV IE G +SG +VVIAD Sbjct: 153 TTSWLDGRHVVFGKVVQGMDVVYKIEAEGKQSGTPKSKVVIAD 195
>PPIF_HUMAN (P30405) Peptidyl-prolyl cis-trans isomerase, mitochondrial| precursor (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin F) Length = 207 Score = 213 bits (543), Expect = 3e-55 Identities = 108/196 (55%), Positives = 125/196 (63%) Frame = +2 Query: 17 PEEIPIRAPEFPIPPKTLAPIPIPIPASEMANPKVFFDMTVGGAPAGRIVMELYKDAVPR 196 P +P+R P K P +S NP V+ D+ G P GR+V+EL D VP+ Sbjct: 17 PRSVPLRLPAARACSKGSGD---PSSSSSSGNPLVYLDVDANGKPLGRVVLELKADVVPK 73 Query: 197 TVENFRALCTGEKGVGKSGKPLHYKGSSFHRVIPDFMCQXXXXXXXXXXXXESIYGEKFA 376 T ENFRALCTGEKG G YKGS+FHRVIP FMCQ +SIYG +F Sbjct: 74 TAENFRALCTGEKGFG-------YKGSTFHRVIPSFMCQAGDFTNHNGTGGKSIYGSRFP 126 Query: 377 DEKFVHKHTKPGILSMANAGPNTNGSQFFICTVPCNWLDGKHVVFGEVVEGMDVVKNIEK 556 DE F KH PG+LSMANAGPNTNGSQFFICT+ +WLDGKHVVFG V EGMDVVK IE Sbjct: 127 DENFTLKHVGPGVLSMANAGPNTNGSQFFICTIKTDWLDGKHVVFGHVKEGMDVVKKIES 186 Query: 557 VGSRSGICFKQVVIAD 604 GS+SG K++VI D Sbjct: 187 FGSKSGRTSKKIVITD 202
>CP20A_ARATH (Q9SP02) Peptidyl-prolyl cis-trans isomerase CYP20-1 precursor (EC| 5.2.1.8) (PPIase CYP20-1) (Rotamase cyclophilin-7) (Cyclophilin of 20 kDa 1) Length = 204 Score = 212 bits (540), Expect = 6e-55 Identities = 105/163 (64%), Positives = 121/163 (74%) Frame = +2 Query: 116 KVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVI 295 KV+FD+ + G AGRIVM L+ VP+TVENFRALCTGEKG+GK+GK LHYKGSSFHR+I Sbjct: 36 KVYFDVEIDGKAAGRIVMGLFGKTVPKTVENFRALCTGEKGIGKNGKALHYKGSSFHRII 95 Query: 296 PDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFFICTV 475 P FM Q ESIYGEKFADE F KHT PG LSMANAG +TNGSQFFI TV Sbjct: 96 PSFMLQGGDFTHGNGMGGESIYGEKFADENFKLKHTGPGFLSMANAGQDTNGSQFFITTV 155 Query: 476 PCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRSGICFKQVVIAD 604 +WLDG+HVVFG+VV GMDVV +E G++SG +VVI D Sbjct: 156 TTSWLDGRHVVFGKVVTGMDVVYKVEAEGNQSGTPKSKVVIVD 198
>PPIA_HEMPU (P91791) Peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8) (PPIase)| (Rotamase) (Cyclophilin) (Cyclosporin A-binding protein) Length = 164 Score = 210 bits (535), Expect = 2e-54 Identities = 104/167 (62%), Positives = 118/167 (70%) Frame = +2 Query: 104 MANPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSF 283 MA P+VFFD+ G GRIVMEL D VP+T ENFRALCTGEKG G YKGS+F Sbjct: 1 MAKPQVFFDLQANGENLGRIVMELRADVVPKTAENFRALCTGEKGFG-------YKGSTF 53 Query: 284 HRVIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFF 463 HRVIP FMCQ +SIYGEKFADE F KHT+PGILSMANAG NTNGSQFF Sbjct: 54 HRVIPGFMCQGGDFTRHNGTGGKSIYGEKFADENFTLKHTQPGILSMANAGVNTNGSQFF 113 Query: 464 ICTVPCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRSGICFKQVVIAD 604 ICT +WLDGKHVVFG V +G+D++K +E GS SG K++ IAD Sbjct: 114 ICTAVTSWLDGKHVVFGAVTQGLDIIKKVESYGSDSGKTSKKITIAD 160
>PPIA_DROME (P25007) Peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8) (PPIase)| (Rotamase) (Cyclophilin) (Cyclosporin A-binding protein) Length = 227 Score = 209 bits (531), Expect = 7e-54 Identities = 108/171 (63%), Positives = 121/171 (70%), Gaps = 1/171 (0%) Frame = +2 Query: 95 ASEMAN-PKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYK 271 AS+M+ P+VFFDMT P GRIVMEL D VP+T ENFRALCTGEKG G YK Sbjct: 60 ASKMSTLPRVFFDMTADNEPLGRIVMELRSDVVPKTAENFRALCTGEKGFG-------YK 112 Query: 272 GSSFHRVIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNG 451 GS FHRVIP+FMCQ +SIYG KF DE F KHT GILSMANAG NTNG Sbjct: 113 GSIFHRVIPNFMCQGGDFTNHNGTGGKSIYGNKFPDENFELKHTGSGILSMANAGANTNG 172 Query: 452 SQFFICTVPCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRSGICFKQVVIAD 604 SQFFICTV WLD KHVVFGEVVEG+DVVK IE GS+SG K++++A+ Sbjct: 173 SQFFICTVKTAWLDNKHVVFGEVVEGLDVVKKIESYGSQSGKTSKKIIVAN 223
>PPIA_BLAGE (P54985) Peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8) (PPIase)| (Rotamase) (Cyclophilin) (Cyclosporin A-binding protein) Length = 164 Score = 209 bits (531), Expect = 7e-54 Identities = 104/167 (62%), Positives = 118/167 (70%) Frame = +2 Query: 104 MANPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSF 283 MA+P+VFFDM+ G P GRIVMEL D VP+T ENFRALCTGEKG G YKGS F Sbjct: 1 MAHPRVFFDMSADGQPVGRIVMELRSDVVPKTAENFRALCTGEKGFG-------YKGSRF 53 Query: 284 HRVIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFF 463 HRVIP+FMCQ +SIYG KF DE F KHT PGIL MANAGPNTNGSQFF Sbjct: 54 HRVIPNFMCQGGDFTNHNGTGGKSIYGTKFEDENFQLKHTGPGILWMANAGPNTNGSQFF 113 Query: 464 ICTVPCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRSGICFKQVVIAD 604 I T +WLD +HVVFG VVEGMDVVK +E +GS+SG K++ + D Sbjct: 114 ITTAKTSWLDNRHVVFGSVVEGMDVVKKLESLGSQSGKTNKKIAVVD 160
>PPID_NEUCR (Q9P3X9) 41 kDa peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8)| (PPIase) (Rotamase) (Cyclophilin-41) (CYP-41) Length = 375 Score = 208 bits (529), Expect = 1e-53 Identities = 104/168 (61%), Positives = 118/168 (70%) Frame = +2 Query: 101 EMANPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSS 280 + A +VFFD+T+GG AGRIV ELY D VP+T ENFRALCTGEKGVGK GKPLHYKGS+ Sbjct: 8 KQARSRVFFDITIGGKAAGRIVFELYNDIVPKTAENFRALCTGEKGVGKLGKPLHYKGST 67 Query: 281 FHRVIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQF 460 FHRVI FM Q ESIYG KF DE F KH +P +LSMANAGP TNGSQF Sbjct: 68 FHRVIKQFMIQGGDFTAGNGTGGESIYGAKFEDENFQLKHDRPFLLSMANAGPGTNGSQF 127 Query: 461 FICTVPCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRSGICFKQVVIAD 604 F+ TVP LDGKHVVFGEV+ G VV+ IE + ++ K VIAD Sbjct: 128 FVTTVPTPHLDGKHVVFGEVLSGKSVVRQIENLKTQGDKPTKDAVIAD 175
>PPIA_RAT (P10111) Peptidyl-prolyl cis-trans isomerase A (EC 5.2.1.8) (PPIase| A) (Rotamase A) (Cyclophilin A) (Cyclosporin A-binding protein) (p31) (p1B15) Length = 163 Score = 207 bits (528), Expect = 1e-53 Identities = 101/165 (61%), Positives = 117/165 (70%) Frame = +2 Query: 110 NPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHR 289 NP VFFD+T G P GR+ EL+ D VP+T ENFRAL TGEKG G YKGSSFHR Sbjct: 2 NPTVFFDITADGEPLGRVCFELFADKVPKTAENFRALSTGEKGFG-------YKGSSFHR 54 Query: 290 VIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFFIC 469 +IP FMCQ +SIYGEKF DE F+ KHT PGILSMANAGPNTNGSQFFIC Sbjct: 55 IIPGFMCQGGDFTRHNGTGGKSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFIC 114 Query: 470 TVPCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRSGICFKQVVIAD 604 T WLDGKHVVFG+V EGM +V+ +E+ GSR+G K++ I+D Sbjct: 115 TAKTEWLDGKHVVFGKVKEGMSIVEAMERFGSRNGKTSKKITISD 159
>PPIA_AOTTR (Q6DTV9) Peptidyl-prolyl cis-trans isomerase A (EC 5.2.1.8) (PPIase| A) (Rotamase A) (Cyclophilin A) (Cyclosporin A-binding protein) Length = 163 Score = 207 bits (528), Expect = 1e-53 Identities = 102/165 (61%), Positives = 118/165 (71%) Frame = +2 Query: 110 NPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHR 289 NP VFFD+ V G P GR+ EL+ D VP+T ENFRAL TGEKG G YKGS FHR Sbjct: 2 NPTVFFDIAVDGEPLGRVSFELFADKVPKTAENFRALSTGEKGFG-------YKGSCFHR 54 Query: 290 VIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFFIC 469 +IP FMCQ +SIYGEKF DE F+ KHT PGILSMANAGPNTNGSQFFIC Sbjct: 55 IIPGFMCQGGDFTRHNGTGGKSIYGEKFDDENFILKHTGPGILSMANAGPNTNGSQFFIC 114 Query: 470 TVPCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRSGICFKQVVIAD 604 TV WLDGKHVVFG+V EGM++V+ +E+ GSR+G K++ IAD Sbjct: 115 TVKTEWLDGKHVVFGKVKEGMNIVEAMERFGSRNGKTSKKITIAD 159
>PPIF_RAT (P29117) Peptidyl-prolyl cis-trans isomerase, mitochondrial| precursor (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin F) Length = 206 Score = 207 bits (527), Expect = 2e-53 Identities = 102/169 (60%), Positives = 116/169 (68%) Frame = +2 Query: 98 SEMANPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGS 277 S NP V+ D+ G P GR+V+EL D VP+T ENFRALCTGEKG G YKGS Sbjct: 40 SSSQNPLVYLDVGADGQPLGRVVLELKADVVPKTAENFRALCTGEKGFG-------YKGS 92 Query: 278 SFHRVIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQ 457 +FHRVIP FMCQ +SIYG +F DE F KH PG+LSMANAGPNTNGSQ Sbjct: 93 TFHRVIPAFMCQAGDFTNHNGTGGKSIYGSRFPDENFTLKHVGPGVLSMANAGPNTNGSQ 152 Query: 458 FFICTVPCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRSGICFKQVVIAD 604 FFICT+ +WLDGKHVVFG V EGMDVVK IE GS+SG K++VI D Sbjct: 153 FFICTIKTDWLDGKHVVFGHVKEGMDVVKKIESFGSKSGKTSKKIVITD 201
>PPIF_MOUSE (Q99KR7) Peptidyl-prolyl cis-trans isomerase, mitochondrial| precursor (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin F) Length = 206 Score = 207 bits (527), Expect = 2e-53 Identities = 102/169 (60%), Positives = 115/169 (68%) Frame = +2 Query: 98 SEMANPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGS 277 S NP V+ D+ G P GR+V+EL D VP+T ENFRALCTGEKG G YKGS Sbjct: 40 SSSGNPLVYLDVGADGQPLGRVVLELKADVVPKTAENFRALCTGEKGFG-------YKGS 92 Query: 278 SFHRVIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQ 457 +FHRVIP FMCQ SIYG +F DE F KH PG+LSMANAGPNTNGSQ Sbjct: 93 TFHRVIPAFMCQAGDFTNHNGTGGRSIYGSRFPDENFTLKHVGPGVLSMANAGPNTNGSQ 152 Query: 458 FFICTVPCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRSGICFKQVVIAD 604 FFICT+ +WLDGKHVVFG V EGMDVVK IE GS+SG K++VI D Sbjct: 153 FFICTIKTDWLDGKHVVFGHVKEGMDVVKKIESFGSKSGKTSKKIVITD 201
>CYPH_ALLCE (P34887) Peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8) (PPIase)| (Rotamase) (Cyclophilin) (Cyclosporin A-binding protein) Length = 150 Score = 207 bits (527), Expect = 2e-53 Identities = 103/146 (70%), Positives = 112/146 (76%) Frame = +2 Query: 167 MELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVIPDFMCQXXXXXXXXXXX 346 MEL++D VP+T ENFRALCTGEKG+G KPLHYKGSSFHRVIP FMCQ Sbjct: 1 MELFQDVVPQTAENFRALCTGEKGMGDR-KPLHYKGSSFHRVIPGFMCQGGDFTAGNGTG 59 Query: 347 XESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFFICTVPCNWLDGKHVVFGEVVE 526 ESIYG KF DE F+ KHT PG+LSMANAGP TNGSQFFICT WLDGKHVVFG+VVE Sbjct: 60 GESIYGAKFKDENFIKKHTGPGVLSMANAGPGTNGSQFFICTEKTAWLDGKHVVFGQVVE 119 Query: 527 GMDVVKNIEKVGSRSGICFKQVVIAD 604 GMDVV+ IEKVGS+SG K V IAD Sbjct: 120 GMDVVRAIEKVGSQSGQTKKPVKIAD 145
>PPID_GIBZE (Q4HXF6) Peptidyl-prolyl cis-trans isomerase D (EC 5.2.1.8) (PPIase| D) (Rotamase D) Length = 372 Score = 207 bits (526), Expect = 2e-53 Identities = 100/156 (64%), Positives = 115/156 (73%) Frame = +2 Query: 107 ANPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFH 286 A P+V+FD+++GG GRI MELY D VP+T +NFR+LCTGEKG+GKSGKPLHYKGS FH Sbjct: 9 ARPRVYFDISIGGKSVGRITMELYADLVPKTADNFRSLCTGEKGIGKSGKPLHYKGSVFH 68 Query: 287 RVIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFFI 466 RVI FM Q ESIYG KF DE F KH KP +LSMANAGPNTNGSQFFI Sbjct: 69 RVIKQFMIQGGDFTAGDGTGGESIYGNKFDDEAFPIKHEKPFLLSMANAGPNTNGSQFFI 128 Query: 467 CTVPCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRSG 574 TVP LDGKHVVFGEV+ G VV+ IE + ++SG Sbjct: 129 TTVPTPHLDGKHVVFGEVLNGKSVVRQIENLTTQSG 164
>PPIA_PAPAN (P62941) Peptidyl-prolyl cis-trans isomerase A (EC 5.2.1.8) (PPIase| A) (Rotamase A) (Cyclophilin A) (Cyclosporin A-binding protein) Length = 164 Score = 206 bits (525), Expect = 3e-53 Identities = 101/165 (61%), Positives = 117/165 (70%) Frame = +2 Query: 110 NPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHR 289 NP VFFD+ V G P GR+ EL+ D VP+T ENFRAL TGEKG G YKGS FHR Sbjct: 2 NPTVFFDIAVDGEPLGRVSFELFADKVPKTAENFRALSTGEKGFG-------YKGSCFHR 54 Query: 290 VIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFFIC 469 +IP FMCQ +SIYGEKF DE F+ KHT PGILSMANAGPNTNGSQFFIC Sbjct: 55 IIPGFMCQGGDFTRHNGTGGKSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFIC 114 Query: 470 TVPCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRSGICFKQVVIAD 604 T WLDGKHVVFG+V EGM++V+ +E+ GSR+G K++ IAD Sbjct: 115 TAKTEWLDGKHVVFGKVKEGMNIVEAMERFGSRNGKTSKKITIAD 159
>PPIA_MACMU (P62940) Peptidyl-prolyl cis-trans isomerase A (EC 5.2.1.8) (PPIase| A) (Rotamase A) (Cyclophilin A) (Cyclosporin A-binding protein) Length = 164 Score = 206 bits (525), Expect = 3e-53 Identities = 101/165 (61%), Positives = 117/165 (70%) Frame = +2 Query: 110 NPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHR 289 NP VFFD+ V G P GR+ EL+ D VP+T ENFRAL TGEKG G YKGS FHR Sbjct: 2 NPTVFFDIAVDGEPLGRVSFELFADKVPKTAENFRALSTGEKGFG-------YKGSCFHR 54 Query: 290 VIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFFIC 469 +IP FMCQ +SIYGEKF DE F+ KHT PGILSMANAGPNTNGSQFFIC Sbjct: 55 IIPGFMCQGGDFTRHNGTGGKSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFIC 114 Query: 470 TVPCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRSGICFKQVVIAD 604 T WLDGKHVVFG+V EGM++V+ +E+ GSR+G K++ IAD Sbjct: 115 TAKTEWLDGKHVVFGKVKEGMNIVEAMERFGSRNGKTSKKITIAD 159
>PPIA_HUMAN (P62937) Peptidyl-prolyl cis-trans isomerase A (EC 5.2.1.8) (PPIase| A) (Rotamase A) (Cyclophilin A) (Cyclosporin A-binding protein) Length = 164 Score = 206 bits (525), Expect = 3e-53 Identities = 101/165 (61%), Positives = 117/165 (70%) Frame = +2 Query: 110 NPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHR 289 NP VFFD+ V G P GR+ EL+ D VP+T ENFRAL TGEKG G YKGS FHR Sbjct: 2 NPTVFFDIAVDGEPLGRVSFELFADKVPKTAENFRALSTGEKGFG-------YKGSCFHR 54 Query: 290 VIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFFIC 469 +IP FMCQ +SIYGEKF DE F+ KHT PGILSMANAGPNTNGSQFFIC Sbjct: 55 IIPGFMCQGGDFTRHNGTGGKSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFIC 114 Query: 470 TVPCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRSGICFKQVVIAD 604 T WLDGKHVVFG+V EGM++V+ +E+ GSR+G K++ IAD Sbjct: 115 TAKTEWLDGKHVVFGKVKEGMNIVEAMERFGSRNGKTSKKITIAD 159
>PPIA_CERAE (P62938) Peptidyl-prolyl cis-trans isomerase A (EC 5.2.1.8) (PPIase| A) (Rotamase A) (Cyclophilin A) (Cyclosporin A-binding protein) Length = 164 Score = 206 bits (525), Expect = 3e-53 Identities = 101/165 (61%), Positives = 117/165 (70%) Frame = +2 Query: 110 NPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHR 289 NP VFFD+ V G P GR+ EL+ D VP+T ENFRAL TGEKG G YKGS FHR Sbjct: 2 NPTVFFDIAVDGEPLGRVSFELFADKVPKTAENFRALSTGEKGFG-------YKGSCFHR 54 Query: 290 VIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFFIC 469 +IP FMCQ +SIYGEKF DE F+ KHT PGILSMANAGPNTNGSQFFIC Sbjct: 55 IIPGFMCQGGDFTRHNGTGGKSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFIC 114 Query: 470 TVPCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRSGICFKQVVIAD 604 T WLDGKHVVFG+V EGM++V+ +E+ GSR+G K++ IAD Sbjct: 115 TAKTEWLDGKHVVFGKVKEGMNIVEAMERFGSRNGKTSKKITIAD 159
>PPIA_PIG (P62936) Peptidyl-prolyl cis-trans isomerase A (EC 5.2.1.8) (PPIase| A) (Rotamase A) (Cyclophilin A) (Cyclosporin A-binding protein) Length = 163 Score = 206 bits (524), Expect = 4e-53 Identities = 101/165 (61%), Positives = 117/165 (70%) Frame = +2 Query: 110 NPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHR 289 NP VFFD+ V G P GR+ EL+ D VP+T ENFRAL TGEKG G YKGS FHR Sbjct: 2 NPTVFFDIAVDGEPLGRVSFELFADKVPKTAENFRALSTGEKGFG-------YKGSCFHR 54 Query: 290 VIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFFIC 469 +IP FMCQ +SIYGEKF DE F+ KHT PGILSMANAGPNTNGSQFFIC Sbjct: 55 IIPGFMCQGGDFTRHNGTGGKSIYGEKFDDENFILKHTGPGILSMANAGPNTNGSQFFIC 114 Query: 470 TVPCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRSGICFKQVVIAD 604 T WLDGKHVVFG+V EGM++V+ +E+ GSR+G K++ IAD Sbjct: 115 TAKTEWLDGKHVVFGKVKEGMNIVEAMERFGSRNGKTSKKITIAD 159
>PPIA_BOVIN (P62935) Peptidyl-prolyl cis-trans isomerase A (EC 5.2.1.8) (PPIase| A) (Rotamase A) (Cyclophilin A) (Cyclosporin A-binding protein) Length = 163 Score = 206 bits (524), Expect = 4e-53 Identities = 101/165 (61%), Positives = 117/165 (70%) Frame = +2 Query: 110 NPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHR 289 NP VFFD+ V G P GR+ EL+ D VP+T ENFRAL TGEKG G YKGS FHR Sbjct: 2 NPTVFFDIAVDGEPLGRVSFELFADKVPKTAENFRALSTGEKGFG-------YKGSCFHR 54 Query: 290 VIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFFIC 469 +IP FMCQ +SIYGEKF DE F+ KHT PGILSMANAGPNTNGSQFFIC Sbjct: 55 IIPGFMCQGGDFTRHNGTGGKSIYGEKFDDENFILKHTGPGILSMANAGPNTNGSQFFIC 114 Query: 470 TVPCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRSGICFKQVVIAD 604 T WLDGKHVVFG+V EGM++V+ +E+ GSR+G K++ IAD Sbjct: 115 TAKTEWLDGKHVVFGKVKEGMNIVEAMERFGSRNGKTSKKITIAD 159
>CYPX_USEUD (P35627) Peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8) (PPIase)| (Rotamase) (Cyclophilin) (Cyclosporin A-binding protein) Length = 169 Score = 206 bits (524), Expect = 4e-53 Identities = 102/151 (67%), Positives = 114/151 (75%) Frame = +2 Query: 122 FFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVIPD 301 FFDMT+GG PAGRI+MEL+ D VP+T ENFRALCTGEKG+G SGK + Y+GS FHRVIP Sbjct: 5 FFDMTIGGQPAGRIIMELFPD-VPKTAENFRALCTGEKGIGPSGKKMTYEGSVFHRVIPK 63 Query: 302 FMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFFICTVPC 481 FM Q ESIYG KFADE F+HKHT PG+LSMANAGP TNGSQFFI TV Sbjct: 64 FMLQGGDFTLGNGRGGESIYGAKFADENFIHKHTTPGLLSMANAGPGTNGSQFFITTVAT 123 Query: 482 NWLDGKHVVFGEVVEGMDVVKNIEKVGSRSG 574 LDGKHVVFG+VVEGMDVV+ IE + G Sbjct: 124 PHLDGKHVVFGKVVEGMDVVRKIEATQTDRG 154
>PPIA_CRIGR (P14851) Peptidyl-prolyl cis-trans isomerase A (EC 5.2.1.8) (PPIase| A) (Rotamase A) (Cyclophilin A) (Cyclosporin A-binding protein) Length = 163 Score = 206 bits (523), Expect = 6e-53 Identities = 100/165 (60%), Positives = 117/165 (70%) Frame = +2 Query: 110 NPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHR 289 NP VFFD++ G P GR+ EL+ D VP+T ENFRAL TGEKG G YKGSSFHR Sbjct: 2 NPTVFFDISADGEPLGRVSFELFADKVPKTAENFRALSTGEKGFG-------YKGSSFHR 54 Query: 290 VIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFFIC 469 +IP FMCQ SIYGEKF DE F+ KHT PGILSMANAGPNTNGSQFFIC Sbjct: 55 IIPGFMCQGGDFTRHNGTGGRSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFIC 114 Query: 470 TVPCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRSGICFKQVVIAD 604 T WLDGKHVVFG+V EGM++V+ +E+ GSR+G K++ I+D Sbjct: 115 TAKTEWLDGKHVVFGKVKEGMNIVEAMERFGSRNGKTSKKITISD 159
>PPIA_MOUSE (P17742) Peptidyl-prolyl cis-trans isomerase A (EC 5.2.1.8) (PPIase| A) (Rotamase A) (Cyclophilin A) (Cyclosporin A-binding protein) (SP18) Length = 163 Score = 204 bits (520), Expect = 1e-52 Identities = 100/165 (60%), Positives = 116/165 (70%) Frame = +2 Query: 110 NPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHR 289 NP VFFD+T P GR+ EL+ D VP+T ENFRAL TGEKG G YKGSSFHR Sbjct: 2 NPTVFFDITADDEPLGRVSFELFADKVPKTAENFRALSTGEKGFG-------YKGSSFHR 54 Query: 290 VIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFFIC 469 +IP FMCQ SIYGEKF DE F+ KHT PGILSMANAGPNTNGSQFFIC Sbjct: 55 IIPGFMCQGGDFTRHNGTGGRSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFIC 114 Query: 470 TVPCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRSGICFKQVVIAD 604 T WLDGKHVVFG+V EGM++V+ +E+ GSR+G K++ I+D Sbjct: 115 TAKTEWLDGKHVVFGKVKEGMNIVEAMERFGSRNGKTSKKITISD 159
>PPIA_PONPY (Q5R8S7) Peptidyl-prolyl cis-trans isomerase A (EC 5.2.1.8) (PPIase| A) (Rotamase A) (Cyclophilin A) (Cyclosporin A-binding protein) Length = 164 Score = 204 bits (519), Expect = 2e-52 Identities = 100/165 (60%), Positives = 116/165 (70%) Frame = +2 Query: 110 NPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHR 289 NP VF D+ V G P GR+ EL+ D VP+T ENFRAL TGEKG G YKGS FHR Sbjct: 2 NPTVFLDIAVDGEPLGRVSFELFADKVPKTAENFRALSTGEKGFG-------YKGSCFHR 54 Query: 290 VIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFFIC 469 +IP FMCQ +SIYGEKF DE F+ KHT PGILSMANAGPNTNGSQFFIC Sbjct: 55 IIPGFMCQGGDFTRHNGTGGKSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFIC 114 Query: 470 TVPCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRSGICFKQVVIAD 604 T WLDGKHVVFG+V EGM++V+ +E+ GSR+G K++ IAD Sbjct: 115 TAKTEWLDGKHVVFGKVKEGMNIVEAMERFGSRNGKTSKKITIAD 159
>PPIA_FELCA (Q8HXS3) Peptidyl-prolyl cis-trans isomerase A (EC 5.2.1.8) (PPIase| A) (Rotamase A) (Cyclophilin A) (Cyclosporin A-binding protein) Length = 163 Score = 203 bits (516), Expect = 4e-52 Identities = 100/165 (60%), Positives = 116/165 (70%) Frame = +2 Query: 110 NPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHR 289 NP VFFD+ V G P GR+ +L+ D VP+T ENFRAL TGEKG G YKGS FHR Sbjct: 2 NPIVFFDIAVDGEPLGRVSFDLFADKVPKTAENFRALSTGEKGFG-------YKGSCFHR 54 Query: 290 VIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFFIC 469 +IP FMCQ +SIYGEKF DE F+ KHT PGILSMANAGPNTNGSQFFIC Sbjct: 55 IIPGFMCQGGDFTRHNGTGGKSIYGEKFDDENFILKHTGPGILSMANAGPNTNGSQFFIC 114 Query: 470 TVPCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRSGICFKQVVIAD 604 T WLDGKHVVFG V EGM++V+ +E+ GSR+G K++ IAD Sbjct: 115 TAKTEWLDGKHVVFGMVKEGMNIVEAMERFGSRNGKTSKKITIAD 159
>PPIA_CANAL (P22011) Peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8) (PPIase)| (Rotamase) (Cyclophilin) (Cyclosporin A-binding protein) (CPH) Length = 162 Score = 201 bits (511), Expect = 1e-51 Identities = 98/162 (60%), Positives = 114/162 (70%) Frame = +2 Query: 119 VFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVIP 298 V+FD++ G G+I +LY D VP+T ENFRALCTGEKG G YKGS FHRVIP Sbjct: 4 VYFDVSADGQKLGKITFKLYDDVVPKTAENFRALCTGEKGFG-------YKGSIFHRVIP 56 Query: 299 DFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFFICTVP 478 FM Q +SIYG KFADE FV +H +PG+LSMANAGPNTNGSQFFI TVP Sbjct: 57 QFMLQGGDFTNFNGTGGKSIYGTKFADENFVKRHDRPGLLSMANAGPNTNGSQFFITTVP 116 Query: 479 CNWLDGKHVVFGEVVEGMDVVKNIEKVGSRSGICFKQVVIAD 604 C WLDGKHVVFGEV +G+D+VK IE GS SG K++VI + Sbjct: 117 CPWLDGKHVVFGEVTDGLDIVKKIESFGSGSGATSKKIVIEE 158
>PPIF_BOVIN (P30404) Peptidyl-prolyl cis-trans isomerase, mitochondrial| precursor (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin F) Length = 209 Score = 201 bits (511), Expect = 1e-51 Identities = 98/160 (61%), Positives = 111/160 (69%) Frame = +2 Query: 95 ASEMANPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKG 274 +S NP V+ D+ G P GR+V+EL D VP+T ENFRALCTGEKG G YKG Sbjct: 41 SSSSGNPLVYLDVGADGQPLGRVVLELKADVVPKTAENFRALCTGEKGFG-------YKG 93 Query: 275 SSFHRVIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGS 454 S+FHRVIP FMCQ +SIYG +F DE F KH PG+LSMANAGPNTNGS Sbjct: 94 STFHRVIPSFMCQAGDFTNHNGTGGKSIYGSRFPDENFKLKHEGPGVLSMANAGPNTNGS 153 Query: 455 QFFICTVPCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRSG 574 QFFICT+ +WLDGKHVVFG V EGMDVVK IE GS+SG Sbjct: 154 QFFICTIKTDWLDGKHVVFGHVKEGMDVVKKIESFGSKSG 193
>PPIA_RABIT (Q9TTC6) Peptidyl-prolyl cis-trans isomerase A (EC 5.2.1.8) (PPIase| A) (Rotamase A) (Cyclophilin A) (Cyclosporin A-binding protein) (Cyclophilin 18) Length = 163 Score = 200 bits (508), Expect = 3e-51 Identities = 99/165 (60%), Positives = 113/165 (68%) Frame = +2 Query: 110 NPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHR 289 NP VFFD+ V G P GR+ EL+ D VP+T ENFRAL TGEKG G YKGS FHR Sbjct: 2 NPTVFFDIAVDGEPLGRVSFELFADKVPKTAENFRALSTGEKGFG-------YKGSCFHR 54 Query: 290 VIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFFIC 469 +IP FMCQ +SIYGEKF DE F+ KHT PGILSMANAGPNTNGSQFFIC Sbjct: 55 IIPGFMCQGGDFTRHNGTGGKSIYGEKFEDENFLLKHTGPGILSMANAGPNTNGSQFFIC 114 Query: 470 TVPCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRSGICFKQVVIAD 604 T WLDGKHVVFG V EGM +V+ +E GS +G K++ IA+ Sbjct: 115 TAKTEWLDGKHVVFGRVKEGMSIVEAMEHFGSENGKTSKKITIAN 159
>CYPH_YEAST (P14832) Peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8) (PPIase)| (Rotamase) (Cyclophilin) (Cyclosporin A-binding protein) (CPH) (PPI-II) Length = 161 Score = 200 bits (508), Expect = 3e-51 Identities = 97/162 (59%), Positives = 113/162 (69%) Frame = +2 Query: 116 KVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVI 295 +V+FD+ G P GR+V +LY D VP+T ENFRALCTGEKG G Y GS FHRVI Sbjct: 2 QVYFDVEADGQPIGRVVFKLYNDIVPKTAENFRALCTGEKGFG-------YAGSPFHRVI 54 Query: 296 PDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFFICTV 475 PDFM Q +SIYG KF DE F H +PG+LSMANAGPNTNGSQFFI TV Sbjct: 55 PDFMLQGGDFTAGNGTGGKSIYGGKFPDENFKKHHDRPGLLSMANAGPNTNGSQFFITTV 114 Query: 476 PCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRSGICFKQVVIA 601 PC WLDGKHVVFGEVV+G D+VK +E +GS SG ++V+A Sbjct: 115 PCPWLDGKHVVFGEVVDGYDIVKKVESLGSPSGATKARIVVA 156
>CYPC_YEAST (P25719) Peptidyl-prolyl cis-trans isomerase C, mitochondrial| precursor (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin C) (PPI-III) Length = 182 Score = 199 bits (506), Expect = 5e-51 Identities = 101/163 (61%), Positives = 112/163 (68%) Frame = +2 Query: 116 KVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVI 295 KVFFD V G GRI ELY + VP+T ENFRALCTGEKG G YKG FHR+I Sbjct: 23 KVFFDPAVNGTKIGRIEFELYDNVVPKTAENFRALCTGEKGWG-------YKGVPFHRII 75 Query: 296 PDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFFICTV 475 PDFM Q +SIYG KFADE FV KH K G+LSMANAGPNTNGSQFFI TV Sbjct: 76 PDFMIQGGDTDLTNGFGGKSIYGSKFADENFVKKHDKAGLLSMANAGPNTNGSQFFITTV 135 Query: 476 PCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRSGICFKQVVIAD 604 PC WLDGKHVVFGEV +GMD+VK IE G+ SG ++VI + Sbjct: 136 PCPWLDGKHVVFGEVTKGMDIVKAIESYGTASGKPRAEIVIEE 178
>PPIE_MOUSE (Q9QZH3) Peptidyl-prolyl cis-trans isomerase E (EC 5.2.1.8) (PPIase| E) (Rotamase E) (Cyclophilin E) (Cyclophilin 33) Length = 301 Score = 198 bits (503), Expect = 1e-50 Identities = 101/187 (54%), Positives = 122/187 (65%) Frame = +2 Query: 44 EFPIPPKTLAPIPIPIPASEMANPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALC 223 E P PPK A P +NP+V+ D+ +G PAGRI M L D VP T ENFR LC Sbjct: 117 EGPEPPKAEAQEGEPTAKKARSNPQVYMDIKIGNKPAGRIQMLLRSDVVPMTAENFRCLC 176 Query: 224 TGEKGVGKSGKPLHYKGSSFHRVIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHT 403 T EKG G +KGSSFHR+IP FMCQ +SIYG+KF DE F+ KHT Sbjct: 177 THEKGFG-------FKGSSFHRIIPQFMCQGGDFTNHNGTGGKSIYGKKFDDENFILKHT 229 Query: 404 KPGILSMANAGPNTNGSQFFICTVPCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRSGICF 583 PG+LSMAN+GPNTNGSQFF+ +WLDGKHVVFGEV EG+DV++ IE GS+ G Sbjct: 230 GPGLLSMANSGPNTNGSQFFLTCDKTDWLDGKHVVFGEVTEGLDVLRQIEAQGSKDGKPK 289 Query: 584 KQVVIAD 604 ++V+IAD Sbjct: 290 QKVMIAD 296
>PPIA_ECHGR (P14088) Peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8) (PPIase)| (Rotamase) (Cyclophilin) (Cyclosporin A-binding protein) (EGCyP-1) Length = 162 Score = 198 bits (503), Expect = 1e-50 Identities = 101/163 (61%), Positives = 116/163 (71%) Frame = +2 Query: 116 KVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVI 295 K FFD+++GG PAGRIV L+ D VP+TVENFRALCTGEKG G YKGS FHR+I Sbjct: 4 KCFFDISIGGKPAGRIVFALFDD-VPKTVENFRALCTGEKGFG-------YKGSKFHRII 55 Query: 296 PDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFFICTV 475 P FMCQ +SIYG KF DE F HKH+KP +LSMANAG NTNGSQFFI T Sbjct: 56 PGFMCQGGDFTAGNGTGGKSIYGSKFEDENFNHKHSKPMMLSMANAGKNTNGSQFFITTA 115 Query: 476 PCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRSGICFKQVVIAD 604 +WLDGKHVVFGEV G DVVK++E VGS SG ++V+I D Sbjct: 116 VTSWLDGKHVVFGEVESGEDVVKDMEAVGSSSGKTSQEVLITD 158
>PPID_BOVIN (P26882) 40 kDa peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8)| (PPIase) (Rotamase) (Cyclophilin-40) (CYP-40) (Cyclophilin-related protein) (Estrogen receptor-binding cyclophilin) Length = 369 Score = 197 bits (502), Expect = 2e-50 Identities = 100/170 (58%), Positives = 119/170 (70%), Gaps = 1/170 (0%) Frame = +2 Query: 98 SEMANPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKS-GKPLHYKG 274 S +NP+VFFD+ +GG GRIV+EL+ D VP+T ENFRALCTGEKG+G + GKPLH+KG Sbjct: 10 SNPSNPRVFFDVDIGGERVGRIVLELFADIVPKTAENFRALCTGEKGIGPTTGKPLHFKG 69 Query: 275 SSFHRVIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGS 454 FHR+I FM Q ESIYGEKF DE F +KH K G+LSMANAG NTNGS Sbjct: 70 CPFHRIIKKFMIQGGDFSNQNGTGGESIYGEKFEDENFHYKHDKEGLLSMANAGSNTNGS 129 Query: 455 QFFICTVPCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRSGICFKQVVIAD 604 QFFI TVP LDGKHVVFG+V++GM V K +E V + K VIA+ Sbjct: 130 QFFITTVPTPHLDGKHVVFGQVIKGMGVAKILENVEVKGEKPAKLCVIAE 179
>PPIE_HUMAN (Q9UNP9) Peptidyl-prolyl cis-trans isomerase E (EC 5.2.1.8) (PPIase| E) (Rotamase E) (Cyclophilin E) (Cyclophilin 33) Length = 301 Score = 197 bits (500), Expect = 3e-50 Identities = 99/183 (54%), Positives = 120/183 (65%) Frame = +2 Query: 56 PPKTLAPIPIPIPASEMANPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEK 235 PPK PI +NP+V+ D+ +G PAGRI M L D VP T ENFR LCT EK Sbjct: 121 PPKAETQEGEPIAKKARSNPQVYMDIKIGNKPAGRIQMLLRSDVVPMTAENFRCLCTHEK 180 Query: 236 GVGKSGKPLHYKGSSFHRVIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGI 415 G G +KGSSFHR+IP FMCQ +SIYG+KF DE F+ KHT PG+ Sbjct: 181 GFG-------FKGSSFHRIIPQFMCQGGDFTNHNGTGGKSIYGKKFDDENFILKHTGPGL 233 Query: 416 LSMANAGPNTNGSQFFICTVPCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRSGICFKQVV 595 LSMAN+GPNTNGSQFF+ +WLDGKHVVFGEV EG+DV++ IE GS+ G ++V+ Sbjct: 234 LSMANSGPNTNGSQFFLTCDKTDWLDGKHVVFGEVTEGLDVLRQIEAQGSKDGKPKQKVI 293 Query: 596 IAD 604 IAD Sbjct: 294 IAD 296
>PPID_EMENI (Q5B4E7) Peptidyl-prolyl cis-trans isomerase D (EC 5.2.1.8) (PPIase| D) (Rotamase D) Length = 372 Score = 197 bits (500), Expect = 3e-50 Identities = 97/169 (57%), Positives = 115/169 (68%) Frame = +2 Query: 98 SEMANPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGS 277 +E P+VFFD+ +G GRI EL+ D VP+T ENFRALCTGEKG+GK GKPLH+KGS Sbjct: 2 AESKRPRVFFDIQIGQQQTGRIAFELFNDVVPKTAENFRALCTGEKGMGKQGKPLHFKGS 61 Query: 278 SFHRVIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQ 457 FHRVI FM Q ESIYGEKF DE F KH +P +LSMAN+GP TNGSQ Sbjct: 62 IFHRVIKQFMIQGGDFTAFNGTGGESIYGEKFPDENFELKHDRPFLLSMANSGPGTNGSQ 121 Query: 458 FFICTVPCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRSGICFKQVVIAD 604 FFI TVP LDGKHVVFGEV+ G VV+ IE + +++ V IA+ Sbjct: 122 FFITTVPTPHLDGKHVVFGEVINGKSVVRKIENMPTQADKPTTDVTIAE 170
>PPID_MOUSE (Q9CR16) 40 kDa peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8)| (PPIase) (Rotamase) (Cyclophilin-40) (CYP-40) Length = 369 Score = 196 bits (499), Expect = 3e-50 Identities = 98/170 (57%), Positives = 117/170 (68%), Gaps = 1/170 (0%) Frame = +2 Query: 98 SEMANPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKS-GKPLHYKG 274 S NP+VFFD+ +GG GRIV+EL+ D VP+T ENFRALCTGEKG G + GKPLH+KG Sbjct: 10 SNSKNPRVFFDVDIGGERVGRIVLELFADIVPKTAENFRALCTGEKGTGSTTGKPLHFKG 69 Query: 275 SSFHRVIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGS 454 FHR+I FM Q ESIYGEKF DE F +KH + G+LSMANAGPNTNGS Sbjct: 70 CPFHRIIKKFMIQGGDFSNQNGTGGESIYGEKFEDENFHYKHDREGLLSMANAGPNTNGS 129 Query: 455 QFFICTVPCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRSGICFKQVVIAD 604 QFFI TVP LDGKHVVFG+V++G+ V + +E V K VIA+ Sbjct: 130 QFFITTVPTPHLDGKHVVFGQVIKGLGVARTLENVEVNGEKPAKLCVIAE 179
>PPID_RAT (Q6DGG0) 40 kDa peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8)| (PPIase) (Rotamase) (Cyclophilin-40) (CYP-40) Length = 369 Score = 196 bits (498), Expect = 4e-50 Identities = 101/177 (57%), Positives = 120/177 (67%), Gaps = 4/177 (2%) Frame = +2 Query: 86 PIPA---SEMANPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKS-G 253 P PA S NP+VFFD+ +GG GRIV+EL+ D VP+T ENFRALCTGEKG G + G Sbjct: 3 PSPAGKPSNSKNPRVFFDVDIGGERVGRIVLELFADIVPKTAENFRALCTGEKGTGPTTG 62 Query: 254 KPLHYKGSSFHRVIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANA 433 KPLH+KG FHR+I FM Q ESIYGEKF DE F +KH + G+LSMANA Sbjct: 63 KPLHFKGCPFHRIIKKFMIQGGDFSNQNGTGGESIYGEKFEDENFHYKHDREGLLSMANA 122 Query: 434 GPNTNGSQFFICTVPCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRSGICFKQVVIAD 604 GPNTNGSQFFI TVP LDGKHVVFG+V++G+ V + +E V K VIA+ Sbjct: 123 GPNTNGSQFFITTVPTPHLDGKHVVFGQVIKGLGVARMLENVEVNGEKPAKLCVIAE 179
>CYPH_SCHPO (P18253) Peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8) (PPIase)| (Rotamase) (Cyclophilin) (Cyclosporin A-binding protein) (CPH) Length = 162 Score = 195 bits (496), Expect = 7e-50 Identities = 98/159 (61%), Positives = 109/159 (68%) Frame = +2 Query: 122 FFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVIPD 301 FFD+ G P GRIV +L+ D VP+T NFRALCTGEKG G Y GS+FHRVIP Sbjct: 5 FFDVIANGQPLGRIVFKLFDDVVPKTAANFRALCTGEKGYG-------YAGSTFHRVIPQ 57 Query: 302 FMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFFICTVPC 481 FM Q +SIYGEKF DE F KH KPG+LSMANAGPNTNGSQFFI TV Sbjct: 58 FMLQGGDFTRGNGTGGKSIYGEKFPDENFALKHNKPGLLSMANAGPNTNGSQFFITTVVT 117 Query: 482 NWLDGKHVVFGEVVEGMDVVKNIEKVGSRSGICFKQVVI 598 WLDGKHVVFGEV EGMDVVK +E +GS SG ++VI Sbjct: 118 PWLDGKHVVFGEVTEGMDVVKKVESLGSNSGATRARIVI 156
>PPID_AMAMU (Q5U8Z7) Peptidyl-prolyl cis-trans isomerase D (EC 5.2.1.8) (PPIase| D) (Rotamase D) Length = 371 Score = 195 bits (495), Expect = 1e-49 Identities = 100/165 (60%), Positives = 116/165 (70%), Gaps = 1/165 (0%) Frame = +2 Query: 113 PKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRV 292 P VFFD+ +GG AGR+ LY D VP+T ENFRALCTGEKG+G+SGKPL YKGS+FHRV Sbjct: 5 PIVFFDIAIGGQLAGRVAFRLYSDLVPKTAENFRALCTGEKGLGQSGKPLWYKGSAFHRV 64 Query: 293 IPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFFICT 472 I FMCQ ESIYGEKF DE F H++P +LSMANAGPNTNGSQFFI Sbjct: 65 IKGFMCQGGDFTAGNGTGGESIYGEKFEDEGFPVHHSRPFLLSMANAGPNTNGSQFFITV 124 Query: 473 VPCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRSGICFKQ-VVIAD 604 LDGKHVVFGEV++G VV+ IE + +G K+ VVIAD Sbjct: 125 SATPHLDGKHVVFGEVIKGRSVVRTIENNPATNGDVPKEPVVIAD 169
>PPID_DEBHA (Q6BXZ7) Peptidyl-prolyl cis-trans isomerase D (EC 5.2.1.8) (PPIase| D) (Rotamase D) Length = 370 Score = 194 bits (494), Expect = 1e-49 Identities = 94/155 (60%), Positives = 111/155 (71%), Gaps = 1/155 (0%) Frame = +2 Query: 95 ASEMANPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKS-GKPLHYK 271 + ++ PKVFFD++ G P GR+V ELY D VP+T ENFRALCTGEKG +S GK LHYK Sbjct: 2 SDKLNRPKVFFDISADGKPKGRVVFELYNDVVPKTAENFRALCTGEKGASESSGKQLHYK 61 Query: 272 GSSFHRVIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNG 451 GS FHR+I DFMCQ ESIYGEKF DE F H KP +LSMANAG NTNG Sbjct: 62 GSIFHRIIKDFMCQGGDFTHGSGIGGESIYGEKFEDENFQLTHDKPFLLSMANAGANTNG 121 Query: 452 SQFFICTVPCNWLDGKHVVFGEVVEGMDVVKNIEK 556 SQFFI TVP L+GKHVVFGEV++G +V+ +E+ Sbjct: 122 SQFFITTVPTPHLNGKHVVFGEVIQGKSIVRQLER 156
>PPIE_SCHMA (Q26548) Peptidyl-prolyl cis-trans isomerase E (EC 5.2.1.8) (PPIase| E) (Rotamase E) (Cyclophilin E) Length = 273 Score = 194 bits (492), Expect = 2e-49 Identities = 96/163 (58%), Positives = 112/163 (68%) Frame = +2 Query: 113 PKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRV 292 P+VFFD+ +G AGRIVMEL D VPRT ENFRALCTGE+G G Y FHRV Sbjct: 112 PRVFFDIRIGNGDAGRIVMELRSDIVPRTAENFRALCTGERGFG-------YHNCCFHRV 164 Query: 293 IPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFFICT 472 IP FMCQ +SIYG KF DE F +H G+LSMAN+GPNTNGSQFFICT Sbjct: 165 IPQFMCQGGDFVKGDGTGGKSIYGRKFDDENFQLRHEGFGVLSMANSGPNTNGSQFFICT 224 Query: 473 VPCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRSGICFKQVVIA 601 C+WLDGKHVVFG VV+G +VVK +E VGS+SG + V+I+ Sbjct: 225 TKCDWLDGKHVVFGRVVDGQNVVKKMESVGSKSGKVKEPVIIS 267
>PPIH_NEUCR (Q7SG06) Peptidyl-prolyl cis-trans isomerase H (EC 5.2.1.8) (PPIase| H) (Rotamase H) Length = 182 Score = 194 bits (492), Expect = 2e-49 Identities = 102/166 (61%), Positives = 115/166 (69%), Gaps = 3/166 (1%) Frame = +2 Query: 80 PIPIPASEMANPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKP 259 P +PAS NP VFFD+T+GG P GRI EL+KD VPRT ENFR CTGE G+P Sbjct: 3 PTVLPAS--GNPLVFFDITLGGEPLGRITFELFKDVVPRTAENFRQFCTGESK-NNLGRP 59 Query: 260 LHYKGSSFHRVIPDFMCQXXXXXXXXXXXXESIYGEK-FADEKFVHKHTKPGILSMANAG 436 YKGS FHR+IP+FMCQ IYG K FADE F+ KH PG+LSMANAG Sbjct: 60 QGYKGSKFHRIIPNFMCQGGDFLNGDGTGSTCIYGTKSFADENFLLKHDTPGLLSMANAG 119 Query: 437 PNTNGSQFFICTVPCNWLDGKHVVFGEVVEGMDVVKNIE--KVGSR 568 PNTNGSQFFI TVP +LDGKHVVFG+VV+GMDVVK +E K G R Sbjct: 120 PNTNGSQFFITTVPTPFLDGKHVVFGKVVDGMDVVKKMENTKTGYR 165
>PPID_HUMAN (Q08752) 40 kDa peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8)| (PPIase) (Rotamase) (Cyclophilin-40) (CYP-40) (Cyclophilin-related protein) Length = 369 Score = 193 bits (491), Expect = 3e-49 Identities = 97/170 (57%), Positives = 119/170 (70%), Gaps = 1/170 (0%) Frame = +2 Query: 98 SEMANPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKS-GKPLHYKG 274 S +NP+VFFD+ +GG GRIV+EL+ D VP+T ENFRALCTGEKG+G + GKPLH+KG Sbjct: 10 SNPSNPRVFFDVDIGGERVGRIVLELFADIVPKTAENFRALCTGEKGIGHTTGKPLHFKG 69 Query: 275 SSFHRVIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGS 454 FHR+I FM Q ESIYGEKF DE F +KH + G+LSMANAG NTNGS Sbjct: 70 CPFHRIIKKFMIQGGDFSNQNGTGGESIYGEKFEDENFHYKHDREGLLSMANAGRNTNGS 129 Query: 455 QFFICTVPCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRSGICFKQVVIAD 604 QFFI TVP LDGKHVVFG+V++G+ V + +E V + K VIA+ Sbjct: 130 QFFITTVPTPHLDGKHVVFGQVIKGIGVARILENVEVKGEKPAKLCVIAE 179
>PPID_ASPOR (Q2U0E0) Peptidyl-prolyl cis-trans isomerase D (EC 5.2.1.8) (PPIase| D) (Rotamase D) Length = 371 Score = 191 bits (486), Expect = 1e-48 Identities = 96/170 (56%), Positives = 113/170 (66%) Frame = +2 Query: 95 ASEMANPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKG 274 A P+VFFD+ +G GRI +EL VP+T ENFRALCTGEKG+GK GKPLH+KG Sbjct: 2 ADSQRRPRVFFDIQIGNEKTGRIALELV--LVPKTAENFRALCTGEKGMGKQGKPLHFKG 59 Query: 275 SSFHRVIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGS 454 S FHRVI FM Q ESIYGEKF DE F KH KP +LSMAN+GP TNGS Sbjct: 60 SIFHRVIKQFMIQGGDFTAFNGTGGESIYGEKFPDENFELKHDKPFLLSMANSGPGTNGS 119 Query: 455 QFFICTVPCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRSGICFKQVVIAD 604 QFFI TVP LDGKHVVFGEV+ G VV+ +E + +++ K V I + Sbjct: 120 QFFITTVPTPHLDGKHVVFGEVINGKSVVRKVENMNTQADKPVKDVTIVE 169
>PPIE_SCHJA (Q26516) Peptidyl-prolyl cis-trans isomerase E (EC 5.2.1.8) (PPIase| E) (Rotamase E) (Cyclophilin E) (Fragment) Length = 179 Score = 191 bits (485), Expect = 1e-48 Identities = 95/163 (58%), Positives = 111/163 (68%) Frame = +2 Query: 113 PKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRV 292 P+VFFD+ +G A GRIVMEL D VPRT ENFRALCTG++G G Y FHRV Sbjct: 18 PRVFFDIRIGNADRGRIVMELRSDIVPRTAENFRALCTGDRGFG-------YHNCCFHRV 70 Query: 293 IPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFFICT 472 IP FMCQ +SIYG KF DE F +H G+LSMAN+GPNTNGSQFFICT Sbjct: 71 IPQFMCQGGDFVKGDGTGGKSIYGRKFDDENFQLRHEGFGVLSMANSGPNTNGSQFFICT 130 Query: 473 VPCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRSGICFKQVVIA 601 C+WLDGKHVVFG VV+G +VVK +E VGS+SG + V I+ Sbjct: 131 TKCDWLDGKHVVFGRVVDGQNVVKKMESVGSKSGKVKEPVTIS 173
>PPIE_DROME (Q9V3G3) Peptidyl-prolyl cis-trans isomerase E (EC 5.2.1.8) (PPIase| E) (Rotamase E) (Cyclophilin E) (Cyclophilin 33) Length = 300 Score = 188 bits (477), Expect = 1e-47 Identities = 95/173 (54%), Positives = 115/173 (66%) Frame = +2 Query: 80 PIPIPASEMANPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKP 259 P I +E NP+VFFD+ +GG AGRIVM L D VP+T ENFR LCT E+G G Sbjct: 128 PAVIEKAEKRNPQVFFDIRIGGNDAGRIVMLLRADVVPKTAENFRQLCTHEQGYG----- 182 Query: 260 LHYKGSSFHRVIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGP 439 YKG SFHRVIP+FMCQ +SIYG+KF DE F KH G LSMAN+G Sbjct: 183 --YKGCSFHRVIPEFMCQGGDFTNNNGTGGKSIYGKKFNDENFNLKHNSFGTLSMANSGA 240 Query: 440 NTNGSQFFICTVPCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRSGICFKQVVI 598 NTNGSQFFICT +WLD KHVVFG V+ G +VV+ +E+ GS+SG +++VI Sbjct: 241 NTNGSQFFICTTKTDWLDNKHVVFGHVISGAEVVRKMERCGSKSGTPSQKIVI 293
>PPID_ASPFU (Q4WIF3) Peptidyl-prolyl cis-trans isomerase D (EC 5.2.1.8) (PPIase| D) (Rotamase D) Length = 377 Score = 187 bits (476), Expect = 2e-47 Identities = 96/174 (55%), Positives = 113/174 (64%), Gaps = 4/174 (2%) Frame = +2 Query: 95 ASEMANPKVFFDMTVGGAPAGRIVMEL----YKDAVPRTVENFRALCTGEKGVGKSGKPL 262 A P+V+FD+ +G AGRI +EL + D VP+T ENFRALCTGEKGVGK KPL Sbjct: 2 AETQRRPRVYFDIQIGSQKAGRIALELVRLPFNDVVPKTAENFRALCTGEKGVGKQRKPL 61 Query: 263 HYKGSSFHRVIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPN 442 YKGS FHRVI FM Q ESIYGEKF DE F KH +P +LSMAN+GP Sbjct: 62 SYKGSIFHRVIKQFMIQGGDFTNFNGTGGESIYGEKFPDENFELKHDRPFLLSMANSGPG 121 Query: 443 TNGSQFFICTVPCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRSGICFKQVVIAD 604 TNGSQFFI TVP LDGKHVVFGEV+ G +V+ IE + +++ V I D Sbjct: 122 TNGSQFFITTVPTPHLDGKHVVFGEVINGKSIVRKIENMPTQADKPTTDVTIVD 175
>CP20C_ARATH (P34791) Peptidyl-prolyl cis-trans isomerase CYP20-3, chloroplast| precursor (EC 5.2.1.8) (PPIase CYP20-3) (Rotamase cyclophilin-4) (Cyclophilin of 20 kDa 3) (Cyclosporin A-binding protein) Length = 260 Score = 187 bits (475), Expect = 2e-47 Identities = 95/160 (59%), Positives = 113/160 (70%) Frame = +2 Query: 92 PASEMANPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYK 271 P +++ N KV+FD+ +GG AGRIVM L+ + VP+TVENFRALCTGEK G YK Sbjct: 89 PQAKVTN-KVYFDVEIGGEVAGRIVMGLFGEVVPKTVENFRALCTGEKKYG-------YK 140 Query: 272 GSSFHRVIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNG 451 GSSFHR+I DFM Q SIYG KF DE F KHT PGILSMANAGPNTNG Sbjct: 141 GSSFHRIIKDFMIQGGDFTEGNGTGGISIYGAKFEDENFTLKHTGPGILSMANAGPNTNG 200 Query: 452 SQFFICTVPCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRS 571 SQFFICTV +WLD KHVVFG+V+EGM +V+ +E +R+ Sbjct: 201 SQFFICTVKTSWLDNKHVVFGQVIEGMKLVRTLESQETRA 240
>PPIH_GIBZE (Q4IPH4) Peptidyl-prolyl cis-trans isomerase H (EC 5.2.1.8) (PPIase| H) (Rotamase H) Length = 182 Score = 185 bits (470), Expect = 8e-47 Identities = 96/164 (58%), Positives = 109/164 (66%), Gaps = 3/164 (1%) Frame = +2 Query: 86 PIPASEMANPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLH 265 P E NP VFFD+T+GG P GRI EL+KD VP+T ENFR CTGE G+P Sbjct: 3 PTKLPESGNPLVFFDITIGGEPLGRITFELFKDVVPKTAENFRQFCTGESKT-PVGRPQG 61 Query: 266 YKGSSFHRVIPDFMCQXXXXXXXXXXXXESIYGEK-FADEKFVHKHTKPGILSMANAGPN 442 YKGS FHR+IP+FMCQ I+G K F DE F KH +PG+LSMANAGPN Sbjct: 62 YKGSKFHRIIPNFMCQGGDFLNGDGTGSTCIWGFKSFEDENFTLKHDQPGLLSMANAGPN 121 Query: 443 TNGSQFFICTVPCNWLDGKHVVFGEVVEGMDVVKNIE--KVGSR 568 TNGSQFFI TVP +LD KHVVFG+V EGMDVVK +E K G R Sbjct: 122 TNGSQFFITTVPTPFLDNKHVVFGKVFEGMDVVKKMEATKTGYR 165
>PPID_CANGA (Q6FNU6) Peptidyl-prolyl cis-trans isomerase D (EC 5.2.1.8) (PPIase| D) (Rotamase D) Length = 371 Score = 185 bits (469), Expect = 1e-46 Identities = 95/159 (59%), Positives = 107/159 (67%), Gaps = 2/159 (1%) Frame = +2 Query: 104 MANPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGK--PLHYKGS 277 M PK +FD+++GG P GRIV ELYKD VP+T ENF LC G+ G+ KS PL YKGS Sbjct: 1 MTRPKAYFDISIGGTPKGRIVFELYKDVVPKTAENFLKLCEGKSGMAKSKPDVPLSYKGS 60 Query: 278 SFHRVIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQ 457 FHRVI DFM Q ESIYGEKF DE F KH KP +LSMANAGPNTNGSQ Sbjct: 61 IFHRVIKDFMIQFGDFTNFDGTGGESIYGEKFEDENFEIKHDKPFLLSMANAGPNTNGSQ 120 Query: 458 FFICTVPCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRSG 574 FI VP LDGKHVVFGEV+EG +V+ IEK + G Sbjct: 121 AFITCVPTPHLDGKHVVFGEVIEGKRLVRLIEKQQTEDG 159
>PPID_YARLI (Q6CBP4) Peptidyl-prolyl cis-trans isomerase D (EC 5.2.1.8) (PPIase| D) (Rotamase D) Length = 367 Score = 184 bits (467), Expect = 2e-46 Identities = 88/151 (58%), Positives = 107/151 (70%) Frame = +2 Query: 104 MANPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSF 283 M NP+VFF++ +GG G+I EL+ D VP+T ENFRALCTGEKG ++G PLH+KGSSF Sbjct: 1 MTNPRVFFEVAIGGKTIGKIYFELFADKVPKTAENFRALCTGEKGNTQAGIPLHFKGSSF 60 Query: 284 HRVIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFF 463 HRVI DFM Q ESIYGEKF DE F + H +P +LSMANAGPNTNGSQFF Sbjct: 61 HRVIKDFMVQGGDFTAGNGTGGESIYGEKFPDEAFPYPHDQPFLLSMANAGPNTNGSQFF 120 Query: 464 ICTVPCNWLDGKHVVFGEVVEGMDVVKNIEK 556 I T LD KHVVFG+++ G +V+ IE+ Sbjct: 121 ITTTETPHLDNKHVVFGKLLSGKGIVRQIER 151
>CP20B_ARATH (Q9ASS6) Peptidyl-prolyl cis-trans isomerase CYP20-2, chloroplast| precursor (EC 5.2.1.8) (PPIase CYP20-2) (Rotamase CYP20-2) (Cyclophilin of 20 kDa 2) (Thylakoid lumen PPIase of 20 kDa) (TLP20) Length = 259 Score = 184 bits (467), Expect = 2e-46 Identities = 101/175 (57%), Positives = 122/175 (69%), Gaps = 4/175 (2%) Frame = +2 Query: 92 PASEMANPKVFFDMTVG---GAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPL 262 P S++ + KV+FD++VG G AGRIV+ LY D VP+TVENFRALCTGEKG G Sbjct: 84 PQSKITH-KVYFDISVGNPVGKLAGRIVIGLYGDDVPQTVENFRALCTGEKGFG------ 136 Query: 263 HYKGSSFHRVIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPN 442 YKGS+FHRVI DFM Q +S+YG F DE F H PG+LSMANAGPN Sbjct: 137 -YKGSTFHRVIRDFMIQGGDFEKGNGTGGKSVYGRTFKDENFKLSHVGPGVLSMANAGPN 195 Query: 443 TNGSQFFICTVPCNWLDGKHVVFGEVVEGMDVVKNIEKVGS-RSGICFKQVVIAD 604 TNGSQFFICT+ +WLDG+HVVFG+V+EGM+VVK IE+ + R K+VVIAD Sbjct: 196 TNGSQFFICTIKTSWLDGRHVVFGQVIEGMEVVKLIEEQETDRGDRPRKKVVIAD 250
>CYP40_ARATH (Q9C566) Peptidyl-prolyl cis-trans isomerase CYP40 (EC 5.2.1.8)| (PPIase CYP40) (Rotamase CYP40) (Cyclophilin-40) (Cyclophilin of 40 kDa) (Protein SQUINT) Length = 361 Score = 183 bits (464), Expect = 4e-46 Identities = 94/166 (56%), Positives = 110/166 (66%), Gaps = 1/166 (0%) Frame = +2 Query: 104 MANPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVG-KSGKPLHYKGSS 280 M K F D+++GG GRIV+ELY D VP+T ENFR LCTGEKG+G +G PLHYKG+ Sbjct: 1 MGRSKCFMDISIGGELEGRIVIELYDDVVPKTAENFRLLCTGEKGLGPNTGVPLHYKGNR 60 Query: 281 FHRVIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQF 460 FHRVI FM Q ESIYG KF DE F KH + G+LSMAN+GPNTNGSQF Sbjct: 61 FHRVIKGFMIQGGDISANDGTGGESIYGLKFDDENFELKHERKGMLSMANSGPNTNGSQF 120 Query: 461 FICTVPCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRSGICFKQVVI 598 FI T + LDGKHVVFG V +GM VV++IE V C Q V+ Sbjct: 121 FITTTRTSHLDGKHVVFGRVTKGMGVVRSIEHVSIEEQSCPSQDVV 166
>PPID_CANAL (Q5ACI8) Peptidyl-prolyl cis-trans isomerase D (EC 5.2.1.8) (PPIase| D) (Rotamase D) Length = 369 Score = 182 bits (463), Expect = 5e-46 Identities = 91/155 (58%), Positives = 107/155 (69%), Gaps = 4/155 (2%) Frame = +2 Query: 104 MANPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVG-KSGKPLHYKGSS 280 M V+FD++ G P GR+V +LY D VP+T NFR+LCTG+KG+ KSGKPL YK S Sbjct: 1 MTATPVYFDISCNGKPKGRVVFKLYDDVVPKTAANFRSLCTGDKGISPKSGKPLSYKDSI 60 Query: 281 FHRVIPDFMCQXXXXXXXXX---XXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNG 451 FHRVI DFMCQ ESIYGEKF DE F H KP +LSMAN+GPNTNG Sbjct: 61 FHRVIKDFMCQGGDFTAPSDHLGTGGESIYGEKFEDENFKLNHNKPFLLSMANSGPNTNG 120 Query: 452 SQFFICTVPCNWLDGKHVVFGEVVEGMDVVKNIEK 556 SQFFI TVP LDGKHVVFGEV+EG +V+ +E+ Sbjct: 121 SQFFITTVPTPHLDGKHVVFGEVIEGKSIVRQLER 155
>CYPB_VICFA (Q41651) Peptidyl-prolyl cis-trans isomerase, chloroplast precursor| (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin) (Cyclosporin A-binding protein) (CYP B) Length = 248 Score = 180 bits (457), Expect = 2e-45 Identities = 88/146 (60%), Positives = 103/146 (70%) Frame = +2 Query: 116 KVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVI 295 K+FFD+ +GG AGRIV+ L+ DAVP+TVENF+ L TG KG G Y+GS FHR+I Sbjct: 83 KIFFDIEIGGESAGRIVIGLFGDAVPKTVENFKTLSTGAKGYG-------YQGSFFHRII 135 Query: 296 PDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFFICTV 475 P+FM Q SIYG KF DE F KH PG+LSMANAGPNTNGSQFFICTV Sbjct: 136 PNFMIQGGDFTEGNGTGGVSIYGSKFEDESFDLKHVGPGVLSMANAGPNTNGSQFFICTV 195 Query: 476 PCNWLDGKHVVFGEVVEGMDVVKNIE 553 P WLD +HVVFG V+EG+DVVK +E Sbjct: 196 PTPWLDNRHVVFGHVIEGLDVVKQLE 221
>PPID_YEAST (P53691) Peptidyl-prolyl cis-trans isomerase CPR6 (EC 5.2.1.8)| (PPIase) (Rotamase) Length = 371 Score = 180 bits (456), Expect = 3e-45 Identities = 91/152 (59%), Positives = 102/152 (67%), Gaps = 2/152 (1%) Frame = +2 Query: 104 MANPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGK--PLHYKGS 277 M PK FFD+++GG P GRIV ELY D VP+T ENF LC G G+ K+ PL YKGS Sbjct: 1 MTRPKTFFDISIGGKPQGRIVFELYNDIVPKTAENFLKLCEGNAGMAKTKPDVPLSYKGS 60 Query: 278 SFHRVIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQ 457 FHRVI DFMCQ ESIY EKF DE F KH KP +LSMANAGPNTNGSQ Sbjct: 61 IFHRVIKDFMCQFGDFTNFNGTGGESIYDEKFEDENFTVKHDKPFLLSMANAGPNTNGSQ 120 Query: 458 FFICTVPCNWLDGKHVVFGEVVEGMDVVKNIE 553 FI VP LDGKHVVFGEV++G +V+ IE Sbjct: 121 AFITCVPTPHLDGKHVVFGEVIQGKRIVRLIE 152
>PPID_KLULA (Q6CL78) Peptidyl-prolyl cis-trans isomerase D (EC 5.2.1.8) (PPIase| D) (Rotamase D) Length = 372 Score = 179 bits (453), Expect = 7e-45 Identities = 91/149 (61%), Positives = 100/149 (67%), Gaps = 2/149 (1%) Frame = +2 Query: 113 PKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGK--PLHYKGSSFH 286 PK FFD+++GG PAGRIV ELY D VP+T ENF LC G G KS PL YKGS FH Sbjct: 6 PKTFFDISIGGKPAGRIVFELYSDVVPKTAENFLKLCEGNSGFAKSKPDIPLSYKGSIFH 65 Query: 287 RVIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFFI 466 RVI FMCQ ESIYGEKF DE F KH KP +LSMANAG NTNGSQ FI Sbjct: 66 RVIKSFMCQFGDFTNFNGTGGESIYGEKFEDENFTLKHDKPFLLSMANAGANTNGSQCFI 125 Query: 467 CTVPCNWLDGKHVVFGEVVEGMDVVKNIE 553 VP LDGKHVVFGEV++G +V+ IE Sbjct: 126 TCVPTPHLDGKHVVFGEVIQGKRLVRTIE 154
>PPIA_STRCH (Q06118) Peptidyl-prolyl cis-trans isomerase A (EC 5.2.1.8) (PPIase| A) (Rotamase A) (Cyclophilin ScCypA) (Cyclophilin homolog) Length = 165 Score = 178 bits (452), Expect = 9e-45 Identities = 96/165 (58%), Positives = 110/165 (66%), Gaps = 2/165 (1%) Frame = +2 Query: 116 KVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVI 295 KV+FD+T+ APAGRI L+ D VP+T ENFRAL TGEKG G Y GSSFHRVI Sbjct: 4 KVYFDITIDDAPAGRITFNLFDDVVPKTAENFRALATGEKGFG-------YAGSSFHRVI 56 Query: 296 PDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFFICTV 475 DFM Q +SIYGEKFADE F KH + G+LSMANAG NTNGSQFFI TV Sbjct: 57 TDFMLQGGDFTRGDGTGGKSIYGEKFADENFQLKHDRVGLLSMANAGKNTNGSQFFITTV 116 Query: 476 PCNWLDGKHVVFGEVV--EGMDVVKNIEKVGSRSGICFKQVVIAD 604 WLDGKHVVFGEV + M +V+ IE +GS SG +V IA+ Sbjct: 117 LTPWLDGKHVVFGEVADDDSMALVRKIEALGSSSGRTSAKVTIAE 161
>PPIA_SCHMA (Q26565) Peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8) (PPIase)| (Rotamase) (Cyclophilin) (Cyclosporin A-binding protein) (p17.7) (Smp17.7) Length = 161 Score = 176 bits (446), Expect = 5e-44 Identities = 92/163 (56%), Positives = 107/163 (65%) Frame = +2 Query: 116 KVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVI 295 K FFD+ G GRI+ EL+ D VP T NFR LCT + G YKGS FHR+I Sbjct: 4 KAFFDIKAGDERLGRIIFELFND-VPDTTRNFRELCTHKNNFG-------YKGSVFHRII 55 Query: 296 PDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFFICTV 475 P FMCQ +SIYG KF DE F HKH + LSMANAGPNTNGSQFFI TV Sbjct: 56 PGFMCQGGDFTNGDGTGGKSIYGNKFKDENFNHKH-EAFSLSMANAGPNTNGSQFFITTV 114 Query: 476 PCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRSGICFKQVVIAD 604 PC+WLDGKHVVFG+VV G+DVVK +E +GS SG K+++I D Sbjct: 115 PCSWLDGKHVVFGKVVSGIDVVKKMESLGSTSGKPSKKIIIED 157
>PPIA_PARPR (O00845) Peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8) (PPIase)| (Rotamase) (Cyclophilin) (Cyclosporin A-binding protein) Length = 162 Score = 176 bits (446), Expect = 5e-44 Identities = 92/157 (58%), Positives = 104/157 (66%) Frame = +2 Query: 104 MANPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSF 283 MAN VFFD+ GG +IV +LY D VP+T NFR L TG +G G YKGS F Sbjct: 1 MAN--VFFDVQFGGDAPKKIVFKLYDDVVPKTAANFRELATGSRGFG-------YKGSVF 51 Query: 284 HRVIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFF 463 HRVI DFM Q +SIYGEKFADE F KHTKP +LSMANAGPNTNGSQFF Sbjct: 52 HRVITDFMAQGGDFTNFNGTGGKSIYGEKFADENFKLKHTKPALLSMANAGPNTNGSQFF 111 Query: 464 ICTVPCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRSG 574 I VPC WLDGKHVVFGEVV+G D ++ +K S+ G Sbjct: 112 ITFVPCPWLDGKHVVFGEVVDGFDTLELFKKNSSQQG 148
>PPIB_ASPNG (Q8X166) Peptidyl-prolyl cis-trans isomerase B precursor (EC| 5.2.1.8) (PPIase B) (Rotamase B) Length = 212 Score = 175 bits (443), Expect = 1e-43 Identities = 89/156 (57%), Positives = 104/156 (66%) Frame = +2 Query: 92 PASEMANPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYK 271 P KVFFD+ G P GR+V+ LY VP+T ENFRAL TGEKG G Y+ Sbjct: 28 PRGPKITSKVFFDIEHGDKPLGRVVLGLYGKTVPKTAENFRALATGEKGFG-------YE 80 Query: 272 GSSFHRVIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNG 451 GS+FHRVI DFM Q +SIYGEKFADE F +HT+ G+LSMANAG +TNG Sbjct: 81 GSTFHRVIKDFMIQGGDFTRGDGTGGKSIYGEKFADENFKLRHTRKGLLSMANAGKDTNG 140 Query: 452 SQFFICTVPCNWLDGKHVVFGEVVEGMDVVKNIEKV 559 SQFFI TVP WLDG+HVVFGEV+EG ++V IE V Sbjct: 141 SQFFITTVPTPWLDGRHVVFGEVLEGYEIVAQIENV 176
>PPIB_ASPFU (Q4WP12) Peptidyl-prolyl cis-trans isomerase B precursor (EC| 5.2.1.8) (PPIase B) (Rotamase B) Length = 209 Score = 174 bits (442), Expect = 1e-43 Identities = 91/161 (56%), Positives = 105/161 (65%) Frame = +2 Query: 92 PASEMANPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYK 271 P KVFFD+ G P GRIV+ LY VP+T ENFRAL TGEKG G Y+ Sbjct: 29 PRGPKITSKVFFDIEHGDKPLGRIVLGLYGKTVPKTAENFRALATGEKGFG-------YE 81 Query: 272 GSSFHRVIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNG 451 GS+FHRVI FM Q +SIYGEKFADE F +HT+ G+LSMANAG +TNG Sbjct: 82 GSTFHRVIKSFMIQGGDFTRGDGTGGKSIYGEKFADENFKLRHTRKGLLSMANAGKDTNG 141 Query: 452 SQFFICTVPCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRSG 574 SQFFI TVP WLDG+HVVFGEV+EG +VV+ IE V G Sbjct: 142 SQFFITTVPTPWLDGRHVVFGEVLEGYEVVEQIENVPKGPG 182
>RBP2_HUMAN (P49792) Ran-binding protein 2 (RanBP2) (Nuclear pore complex protein| Nup358) (Nucleoporin Nup358) (358 kDa nucleoporin) (P270) Length = 3224 Score = 174 bits (441), Expect = 2e-43 Identities = 91/169 (53%), Positives = 105/169 (62%) Frame = +2 Query: 98 SEMANPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGS 277 S+ NP VFFD+ G P GRI MEL+ + VPRT ENFRALCTGEKG G +K S Sbjct: 3059 SKETNPVVFFDVCADGEPLGRITMELFSNIVPRTAENFRALCTGEKGFG-------FKNS 3111 Query: 278 SFHRVIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQ 457 FHRVIPDF+CQ +SIYG+KF DE F KHT PG+LSMAN G NTN SQ Sbjct: 3112 IFHRVIPDFVCQGGDITKHDGTGGQSIYGDKFEDENFDVKHTGPGLLSMANQGQNTNNSQ 3171 Query: 458 FFICTVPCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRSGICFKQVVIAD 604 F I LD KHVVFG V +GMD VK IE GS G +++ I + Sbjct: 3172 FVITLKKAEHLDFKHVVFGFVKDGMDTVKKIESFGSPKGSVCRRITITE 3220
>PPIB_ORPSP (Q01490) Peptidyl-prolyl cis-trans isomerase B precursor (EC| 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin B) Length = 203 Score = 174 bits (441), Expect = 2e-43 Identities = 95/173 (54%), Positives = 111/173 (64%), Gaps = 4/173 (2%) Frame = +2 Query: 68 LAPIPIPIPASEMANPKV----FFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEK 235 LA + + S NPKV +FD+ G GRIV+ LY + VP+TVENFRAL TGEK Sbjct: 11 LAIVALATLVSASTNPKVTNKVYFDIKQGDKDLGRIVLGLYGEVVPKTVENFRALATGEK 70 Query: 236 GVGKSGKPLHYKGSSFHRVIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGI 415 G G YK S FHRVI DFM Q +SIYGE+FADE F +HT PGI Sbjct: 71 GYG-------YKNSKFHRVIKDFMIQGGDFTRGDGTGGKSIYGERFADENFKLRHTGPGI 123 Query: 416 LSMANAGPNTNGSQFFICTVPCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRSG 574 LSMANAG +TNGSQFFI TV +WLDG+HVVFG+V+EGMDVV IE + G Sbjct: 124 LSMANAGRDTNGSQFFITTVTTSWLDGRHVVFGKVIEGMDVVTAIETTKTLPG 176
>RBP2_MOUSE (Q9ERU9) Ran-binding protein 2 (RanBP2)| Length = 3053 Score = 173 bits (439), Expect = 3e-43 Identities = 89/169 (52%), Positives = 107/169 (63%) Frame = +2 Query: 98 SEMANPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGS 277 S+ NP VFFD+ G P GRI+MEL+ + VP+T ENFRALCTGEKG G +K S Sbjct: 2888 SKDTNPVVFFDVCADGEPLGRIIMELFSNIVPQTAENFRALCTGEKGFG-------FKNS 2940 Query: 278 SFHRVIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQ 457 FHRV+PDF+CQ +SIYG+KF DE F KHT PG+LSMAN G NTN SQ Sbjct: 2941 IFHRVVPDFICQGGDITKYNGTGGQSIYGDKFDDENFDLKHTGPGLLSMANYGQNTNSSQ 3000 Query: 458 FFICTVPCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRSGICFKQVVIAD 604 FFI LD KHVVFG V +GMD V+ IE GS G +++ I + Sbjct: 3001 FFITLKKAEHLDFKHVVFGFVKDGMDTVRKIESFGSPKGSVSRRICITE 3049
>CYPH_NEUCR (P10255) Peptidyl-prolyl cis-trans isomerase, mitochondrial| precursor (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin) (Cyclosporin A-binding protein) (CPH) Length = 223 Score = 173 bits (439), Expect = 3e-43 Identities = 92/169 (54%), Positives = 106/169 (62%), Gaps = 16/169 (9%) Frame = +2 Query: 116 KVFFDMTVGG--------------APAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSG 253 KVFFD+ G A +GRI LY D VP+T NF+ LCTG+ G G Sbjct: 46 KVFFDLEWEGPVLGPNNKPTSEIKAQSGRINFTLYDDVVPKTARNFKELCTGQNGFG--- 102 Query: 254 KPLHYKGSSFHRVIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANA 433 YKGSSFHR+IP+FM Q +SIYGEKFADE F KH +PG+LSMANA Sbjct: 103 ----YKGSSFHRIIPEFMLQGGDFTRGNGTGGKSIYGEKFADENFAKKHVRPGLLSMANA 158 Query: 434 GPNTNGSQFFICTVPCNWLDGKHVVFGEVV--EGMDVVKNIEKVGSRSG 574 GPNTNGSQFF+ TVP +WLDG+HVVFGEV E M VVK +E GS SG Sbjct: 159 GPNTNGSQFFVTTVPTSWLDGRHVVFGEVADDESMKVVKALEATGSSSG 207
>PPID_ASHGO (Q75A33) Peptidyl-prolyl cis-trans isomerase D (EC 5.2.1.8) (PPIase| D) (Rotamase D) Length = 369 Score = 172 bits (436), Expect = 7e-43 Identities = 85/149 (57%), Positives = 100/149 (67%), Gaps = 2/149 (1%) Frame = +2 Query: 116 KVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGV--GKSGKPLHYKGSSFHR 289 K +FD+++GG PAGR+V E+Y D P+T ENF LC G+ G K G PL Y+GS FHR Sbjct: 6 KTYFDLSIGGKPAGRVVFEVYSDVTPKTAENFVRLCAGDAGECRTKPGVPLCYQGSLFHR 65 Query: 290 VIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFFIC 469 VI FMCQ ESIYGEKF DE F KH +P +LSMANAGPNTNGSQ FI Sbjct: 66 VIKGFMCQFGDFTNGDGTGGESIYGEKFEDENFARKHDRPFLLSMANAGPNTNGSQCFIT 125 Query: 470 TVPCNWLDGKHVVFGEVVEGMDVVKNIEK 556 P LDGKHVVFGEV++G VV+ IE+ Sbjct: 126 CAPTPHLDGKHVVFGEVIQGKRVVRAIER 154
>PPIB_YARLI (Q6C4W6) Peptidyl-prolyl cis-trans isomerase B precursor (EC| 5.2.1.8) (PPIase B) (Rotamase B) Length = 228 Score = 172 bits (435), Expect = 9e-43 Identities = 95/162 (58%), Positives = 108/162 (66%), Gaps = 2/162 (1%) Frame = +2 Query: 92 PASEMANPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYK 271 P +E+ + KV+FD+ G G+IVM LY D VP+TVENFRALCTGE G G YK Sbjct: 26 PDAEITH-KVYFDIKQGEESLGKIVMGLYGDVVPKTVENFRALCTGETGKG-------YK 77 Query: 272 GSSFHRVIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNG 451 GS FHRVI +FM Q ESIYG KF DE F KHTKP LSMANAG +TNG Sbjct: 78 GSKFHRVIKNFMIQGGDFTRGDGTGGESIYGRKFPDENFQLKHTKPYKLSMANAGRDTNG 137 Query: 452 SQFFICTVPCNWLDGKHVVFGEVVEGMDVVKNIEK--VGSRS 571 SQFFI TV +WLDGKHVVFGEV+EG D+V IE G+RS Sbjct: 138 SQFFITTVVTSWLDGKHVVFGEVLEGQDIVDAIENAPTGARS 179
>CYP1_BRUMA (Q27450) Peptidyl-prolyl cis-trans isomerase 1 (EC 5.2.1.8) (PPIase| 1) (Cyclophilin) (BmCYP-1) Length = 843 Score = 172 bits (435), Expect = 9e-43 Identities = 89/153 (58%), Positives = 103/153 (67%), Gaps = 1/153 (0%) Frame = +2 Query: 116 KVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGK-SGKPLHYKGSSFHRV 292 +VF D+T+ G AGRIVMELY D PRT NF LCTG G GK SGKPLHYKGS+FHRV Sbjct: 8 RVFLDVTIDGNLAGRIVMELYNDIAPRTCNNFLMLCTGMAGTGKISGKPLHYKGSTFHRV 67 Query: 293 IPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFFICT 472 I +FM Q ESIYG F DE+FV KH +P ++SMAN GPNTNGSQFFI T Sbjct: 68 IKNFMIQGGDFTKGDGTGGESIYGGMFDDEEFVMKHDEPFVVSMANKGPNTNGSQFFITT 127 Query: 473 VPCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRS 571 P L+ HVVFG+VV G +VV IE + + S Sbjct: 128 TPAPHLNNIHVVFGKVVSGQEVVTKIEYLKTNS 160
>RBP2_BOVIN (P48820) Ran-binding protein 2 (RanBP2) (Nuclear pore complex protein| Nup358) (Nucleoporin Nup358) (358 kDa nucleoporin) (P270) (Fragment) Length = 1085 Score = 171 bits (433), Expect = 2e-42 Identities = 89/169 (52%), Positives = 105/169 (62%) Frame = +2 Query: 98 SEMANPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGS 277 S+ NP VFFD+ P GRI MEL+ + VP+T ENFRALCTGEKG G +K S Sbjct: 920 SKETNPVVFFDICADDEPLGRITMELFSNIVPKTAENFRALCTGEKGFG-------FKSS 972 Query: 278 SFHRVIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQ 457 FHRVIPDF+CQ SIYG+KF DE F KHT PG+LSMAN G +TN SQ Sbjct: 973 IFHRVIPDFVCQGGDITKHDGTGGRSIYGDKFEDENFDVKHTGPGLLSMANRGQDTNNSQ 1032 Query: 458 FFICTVPCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRSGICFKQVVIAD 604 FFI LD KHVVFG V +GMD VK IE GS G ++++I + Sbjct: 1033 FFITLKKAERLDFKHVVFGFVKDGMDTVKKIESFGSPKGSVSRRIIITE 1081
>PPIB_NEUCR (Q7S7Z6) Peptidyl-prolyl cis-trans isomerase B precursor (EC| 5.2.1.8) (PPIase B) (Rotamase B) Length = 207 Score = 171 bits (432), Expect = 2e-42 Identities = 91/153 (59%), Positives = 104/153 (67%), Gaps = 2/153 (1%) Frame = +2 Query: 116 KVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVI 295 KV+FD+ G P GRIVM LY VP+T ENFRAL TGEKG G Y+GS+FHRVI Sbjct: 36 KVYFDIEQGDKPLGRIVMGLYGKTVPKTAENFRALATGEKGFG-------YEGSTFHRVI 88 Query: 296 PDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFFICTV 475 FM Q +SIYG+KF DE F KH+K G+LSMANAG +TNGSQFFI TV Sbjct: 89 KQFMIQGGDFTKGDGTGGKSIYGDKFPDENFKLKHSKKGLLSMANAGKDTNGSQFFITTV 148 Query: 476 PCNWLDGKHVVFGEVVEGMDVVKNIE--KVGSR 568 +WLDGKHVVFGEV+EG DVV+ IE K G R Sbjct: 149 ITSWLDGKHVVFGEVLEGYDVVEKIENTKTGPR 181
>PPIH_EMENI (Q5AQL0) Peptidyl-prolyl cis-trans isomerase H (EC 5.2.1.8) (PPIase| H) (Rotamase H) Length = 183 Score = 171 bits (432), Expect = 2e-42 Identities = 83/156 (53%), Positives = 106/156 (67%), Gaps = 1/156 (0%) Frame = +2 Query: 89 IPASEMANPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHY 268 +P + +NP VFFD+ +GG P GR+ +EL+ D PRT ENFR CTGE + G+P Y Sbjct: 8 VPQTTSSNPIVFFDVALGGEPLGRLKLELFADVTPRTAENFRQFCTGESK-NQQGRPQGY 66 Query: 269 KGSSFHRVIPDFMCQXXXXXXXXXXXXESIYGE-KFADEKFVHKHTKPGILSMANAGPNT 445 KGS FHRVI DFM Q +IYG KF+DE F +H +PG+LSMAN+GPNT Sbjct: 67 KGSKFHRVIKDFMIQGGDFVNGDGTGSCTIYGTPKFSDENFTLRHDRPGLLSMANSGPNT 126 Query: 446 NGSQFFICTVPCNWLDGKHVVFGEVVEGMDVVKNIE 553 NG QFFI T +L+GKHVVFG+V++GMD+V+ IE Sbjct: 127 NGCQFFITTTATPFLNGKHVVFGQVIDGMDIVRMIE 162
>PPIB_GIBZE (Q4I5R9) Peptidyl-prolyl cis-trans isomerase B precursor (EC| 5.2.1.8) (PPIase B) (Rotamase B) Length = 207 Score = 170 bits (430), Expect = 3e-42 Identities = 88/159 (55%), Positives = 108/159 (67%) Frame = +2 Query: 116 KVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVI 295 KV+FD+T G P GR+VM LY VP T ENFRAL TGEKG G Y+GS+FHRVI Sbjct: 36 KVYFDITQGDQPLGRVVMGLYGKTVPETTENFRALATGEKGFG-------YEGSAFHRVI 88 Query: 296 PDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFFICTV 475 +FM Q +SIYG++F DE F KHTK G+LSMANAG +TNGSQFFI TV Sbjct: 89 KNFMIQGGDFTKGDGTGGKSIYGDRFKDENFKLKHTKKGLLSMANAGRDTNGSQFFITTV 148 Query: 476 PCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRSGICFKQV 592 +WLDGKHVVFGEV+EG ++++ IE S++G + V Sbjct: 149 VTSWLDGKHVVFGEVLEGYEIIEKIE--NSKTGAADRPV 185
>PPIH_HUMAN (O43447) Peptidyl-prolyl cis-trans isomerase H (EC 5.2.1.8) (PPIase| H) (Rotamase H) (U-snRNP-associated cyclophilin SnuCyp-20) (USA-CYP) (Small nuclear ribonucleoprotein particle-specific cyclophilin H) (CypH) Length = 177 Score = 170 bits (430), Expect = 3e-42 Identities = 82/154 (53%), Positives = 104/154 (67%) Frame = +2 Query: 98 SEMANPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGS 277 S NP VFFD+++GG GR+ +EL+ D VP+T ENFR CTGE K G P+ YKGS Sbjct: 6 SSPVNPVVFFDVSIGGQEVGRMKIELFADVVPKTAENFRQFCTGE--FRKDGVPIGYKGS 63 Query: 278 SFHRVIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQ 457 +FHRVI DFM Q SIY FADE F +H+ PG+LSMAN+GP+TNG Q Sbjct: 64 TFHRVIKDFMIQGGDFVNGDGTGVASIYRGPFADENFKLRHSAPGLLSMANSGPSTNGCQ 123 Query: 458 FFICTVPCNWLDGKHVVFGEVVEGMDVVKNIEKV 559 FFI C+WLDGKHVVFG++++G+ V++ IE V Sbjct: 124 FFITCSKCDWLDGKHVVFGKIIDGLLVMRKIENV 157
>PPIG_RAT (O55035) Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8)| (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Matrin cyclophilin) (Matrin-cyp) Length = 752 Score = 169 bits (429), Expect = 4e-42 Identities = 84/152 (55%), Positives = 99/152 (65%), Gaps = 1/152 (0%) Frame = +2 Query: 101 EMANPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSG-KPLHYKGS 277 ++ P+ FFD+ + PAGR+V EL+ D P+T ENFR LCTGEKG GKS KPLHYK Sbjct: 4 KVQRPRCFFDIAINNQPAGRVVFELFSDVCPKTCENFRCLCTGEKGTGKSTQKPLHYKSC 63 Query: 278 SFHRVIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQ 457 FHRV+ DFM Q ESIYG F DE F KH K +LSMAN G +TNGSQ Sbjct: 64 LFHRVVKDFMVQGGDFSEGNGRGGESIYGGFFEDESFAVKHNKEFLLSMANRGKDTNGSQ 123 Query: 458 FFICTVPCNWLDGKHVVFGEVVEGMDVVKNIE 553 FFI T P LDG HVVFG+V+ G +VV+ IE Sbjct: 124 FFITTKPTPHLDGHHVVFGQVISGQEVVREIE 155
>PPIG_HUMAN (Q13427) Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8)| (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10) Length = 754 Score = 169 bits (429), Expect = 4e-42 Identities = 84/152 (55%), Positives = 99/152 (65%), Gaps = 1/152 (0%) Frame = +2 Query: 101 EMANPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSG-KPLHYKGS 277 ++ P+ FFD+ + PAGR+V EL+ D P+T ENFR LCTGEKG GKS KPLHYK Sbjct: 4 KVQRPRCFFDIAINNQPAGRVVFELFSDVCPKTCENFRCLCTGEKGTGKSTQKPLHYKSC 63 Query: 278 SFHRVIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQ 457 FHRV+ DFM Q ESIYG F DE F KH K +LSMAN G +TNGSQ Sbjct: 64 LFHRVVKDFMVQGGDFSEGNGRGGESIYGGFFEDESFAVKHNKEFLLSMANRGKDTNGSQ 123 Query: 458 FFICTVPCNWLDGKHVVFGEVVEGMDVVKNIE 553 FFI T P LDG HVVFG+V+ G +VV+ IE Sbjct: 124 FFITTKPTPHLDGHHVVFGQVISGQEVVREIE 155
>PPIH_ASPFU (Q4WCM6) Peptidyl-prolyl cis-trans isomerase H (EC 5.2.1.8) (PPIase| H) (Rotamase H) Length = 181 Score = 169 bits (429), Expect = 4e-42 Identities = 87/149 (58%), Positives = 100/149 (67%), Gaps = 1/149 (0%) Frame = +2 Query: 110 NPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHR 289 NP VFFD+ +GG P GRI MEL+ D PRT ENFR CTGE GKP YK S FHR Sbjct: 13 NPIVFFDIALGGVPLGRIKMELFADVTPRTAENFRRFCTGESK-NSQGKPQGYKNSKFHR 71 Query: 290 VIPDFMCQXXXXXXXXXXXXESIYGE-KFADEKFVHKHTKPGILSMANAGPNTNGSQFFI 466 VI DFM Q +IYG KFADE FV KH + G+LSMAN+GPNTNG QFFI Sbjct: 72 VIKDFMIQGGDFVNGDGTGSCTIYGTPKFADENFVLKHDRAGVLSMANSGPNTNGCQFFI 131 Query: 467 CTVPCNWLDGKHVVFGEVVEGMDVVKNIE 553 T +L+GKHVVFG+VV+GMD+V+ IE Sbjct: 132 TTTATPFLNGKHVVFGQVVDGMDIVRMIE 160
>CYPH_UROFA (O00060) Peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8) (PPIase)| (Rotamase) (Cyclophilin) (Cyclosporin A-binding protein) (Planta-induced rust protein 28) Length = 163 Score = 169 bits (427), Expect = 7e-42 Identities = 91/158 (57%), Positives = 102/158 (64%), Gaps = 1/158 (0%) Frame = +2 Query: 104 MANPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSF 283 MAN +FD++ G P GRIV ELY D VPRT NFR LC G G +K S F Sbjct: 1 MAN--CYFDVSSNGKPLGRIVFELYDDVVPRTTNNFRQLCLNPPGKG-------FKHSIF 51 Query: 284 HRVIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFF 463 HRVIPDFM Q ESIYG+KF DE F KH + G+LSMANAGPNTNGSQFF Sbjct: 52 HRVIPDFMIQGGDFTNGNGTGGESIYGKKFEDENFQKKHVERGMLSMANAGPNTNGSQFF 111 Query: 464 ICTVPCNWLDGKHVVFGEVVEGMD-VVKNIEKVGSRSG 574 I WLDGKHVVFG+V+EG D VVK +EK GS+SG Sbjct: 112 ITVTKTPWLDGKHVVFGKVIEGYDQVVKAMEKTGSQSG 149
>PPIH_MOUSE (Q9D868) Peptidyl-prolyl cis-trans isomerase H (EC 5.2.1.8) (PPIase| H) (Rotamase H) Length = 188 Score = 168 bits (426), Expect = 1e-41 Identities = 81/152 (53%), Positives = 103/152 (67%) Frame = +2 Query: 98 SEMANPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGS 277 S NP VFFD+++GG GR+ +EL+ D VP+T ENFR CTGE K G P+ YKGS Sbjct: 6 SSPVNPVVFFDVSIGGQEVGRMKIELFADVVPKTAENFRQFCTGE--FRKDGVPIGYKGS 63 Query: 278 SFHRVIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQ 457 +FHRVI DFM Q SIY FADE F +H+ PG+LSMAN+GP+TNG Q Sbjct: 64 TFHRVIKDFMIQGGDFVNGDGTGVASIYRGPFADENFKLRHSAPGLLSMANSGPSTNGCQ 123 Query: 458 FFICTVPCNWLDGKHVVFGEVVEGMDVVKNIE 553 FFI C+WLDGKHVVFG++++G+ V++ IE Sbjct: 124 FFITCSKCDWLDGKHVVFGKIIDGLLVMRKIE 155
>PPIB_ASPOR (Q2UGK2) Peptidyl-prolyl cis-trans isomerase B precursor (EC| 5.2.1.8) (PPIase B) (Rotamase B) Length = 192 Score = 168 bits (425), Expect = 1e-41 Identities = 89/159 (55%), Positives = 106/159 (66%) Frame = +2 Query: 119 VFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVIP 298 V+FD+ G P GR+V+ LY VP+T ENFRAL TGEKG G Y+GS+FHRVI Sbjct: 22 VYFDIEHGNKPLGRVVLGLYGKTVPKTAENFRALATGEKGFG-------YEGSTFHRVIK 74 Query: 299 DFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFFICTVP 478 +FM Q +SIYGEKF DE F +HTK G+LSMANAG +TNGSQFFI TV Sbjct: 75 EFMIQGGDFTRGDGTGGKSIYGEKFKDENFKIRHTKKGLLSMANAGKDTNGSQFFITTVA 134 Query: 479 CNWLDGKHVVFGEVVEGMDVVKNIEKVGSRSGICFKQVV 595 WLDG+HVVFGEV+EG +VV+ IE V G +QVV Sbjct: 135 TPWLDGRHVVFGEVLEGYEVVEAIENVPKVPGDKPQQVV 173
>PPIB_CRYNE (Q5KEB7) Peptidyl-prolyl cis-trans isomerase B precursor (EC| 5.2.1.8) (PPIase B) (Rotamase B) Length = 231 Score = 168 bits (425), Expect = 1e-41 Identities = 87/153 (56%), Positives = 102/153 (66%) Frame = +2 Query: 116 KVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVI 295 KV+FD+ GG P GRIVM LY VP+T ENFRAL TG+ G+ Y+GSSFHR+I Sbjct: 46 KVYFDIEHGGKPLGRIVMGLYGKTVPKTAENFRALATGKNSDGED-LGYGYEGSSFHRII 104 Query: 296 PDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFFICTV 475 +FM Q +SIYG KF DE F KHT PG+LSMANAG +TNGSQFFICTV Sbjct: 105 KNFMIQGGDFTKGDGTGGKSIYGSKFPDENFKLKHTGPGVLSMANAGRDTNGSQFFICTV 164 Query: 476 PCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRSG 574 WLD +HVVFG V+EGMDVV +E V + G Sbjct: 165 KTAWLDNRHVVFGHVLEGMDVVYAMENVKTSRG 197
>PPIB_ARTBE (O93826) Peptidyl-prolyl cis-trans isomerase B precursor (EC| 5.2.1.8) (PPIase B) (Rotamase B) Length = 226 Score = 167 bits (424), Expect = 2e-41 Identities = 87/148 (58%), Positives = 99/148 (66%) Frame = +2 Query: 116 KVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVI 295 KV+FD+ G P GRIVM LY VP+T ENFRAL TGEKG G Y+GS+FHRVI Sbjct: 36 KVYFDIEHDGQPLGRIVMGLYGKTVPKTAENFRALATGEKGFG-------YEGSTFHRVI 88 Query: 296 PDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFFICTV 475 DFM Q +SIYG KF DE F +HTK G+LSMANAG +TNGSQFFI T Sbjct: 89 KDFMIQGGDFTNGDGTGGKSIYGNKFEDENFKLRHTKKGVLSMANAGKDTNGSQFFITTA 148 Query: 476 PCNWLDGKHVVFGEVVEGMDVVKNIEKV 559 WLDGKHVVFGEV+EG D+V I+ V Sbjct: 149 ITAWLDGKHVVFGEVLEGYDIVDKIQVV 176
>PPIB_CHICK (P24367) Peptidyl-prolyl cis-trans isomerase B precursor (EC| 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin B) (S-cyclophilin) (SCYLP) Length = 207 Score = 167 bits (422), Expect = 3e-41 Identities = 93/165 (56%), Positives = 108/165 (65%), Gaps = 2/165 (1%) Frame = +2 Query: 116 KVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVI 295 KVFFD+ VG AGR+V+ L+ VP+TVENF AL TGEKG G +KGS FHRVI Sbjct: 36 KVFFDLRVGEEDAGRVVIGLFGKTVPKTVENFVALATGEKGFG-------FKGSKFHRVI 88 Query: 296 PDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFFICTV 475 DFM Q +SIYG++F DE F KH PG +SMANAG +TNGSQFFI TV Sbjct: 89 KDFMIQGGDFTRGDGTGGKSIYGDRFPDENFKLKHYGPGWVSMANAGKDTNGSQFFITTV 148 Query: 476 PCNWLDGKHVVFGEVVEGMDVVKNIE--KVGSRSGICFKQVVIAD 604 WLDGKHVVFG+V+EGMDVV+ +E K SR K V IAD Sbjct: 149 KTAWLDGKHVVFGKVLEGMDVVRKVENTKTDSRDK-PLKDVTIAD 192
>PPIH_CRYNE (Q5KA96) Peptidyl-prolyl cis-trans isomerase H (EC 5.2.1.8) (PPIase| H) (Rotamase H) Length = 179 Score = 167 bits (422), Expect = 3e-41 Identities = 83/156 (53%), Positives = 101/156 (64%) Frame = +2 Query: 92 PASEMANPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYK 271 P + P VFFD+++G PAGRI MEL+ D P+T ENFR LCTGE + + P YK Sbjct: 6 PPAGHTRPIVFFDISIGDTPAGRIKMELFDDITPKTAENFRQLCTGEHRI--NSVPQGYK 63 Query: 272 GSSFHRVIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNG 451 ++FHRVIP FM Q SIYG +F DE F KHT PG+LSMAN+GPNTNG Sbjct: 64 KATFHRVIPQFMVQGGDFVRGDGTGSFSIYGAQFEDENFKVKHTGPGLLSMANSGPNTNG 123 Query: 452 SQFFICTVPCNWLDGKHVVFGEVVEGMDVVKNIEKV 559 QFFI T P +LDGKH VFG V++G+ V+ IE V Sbjct: 124 CQFFITTAPAEFLDGKHCVFGRVIDGLLTVRKIENV 159
>PPID_USTMA (Q4P0V4) Peptidyl-prolyl cis-trans isomerase D (EC 5.2.1.8) (PPIase| D) (Rotamase D) Length = 398 Score = 166 bits (420), Expect = 5e-41 Identities = 85/155 (54%), Positives = 99/155 (63%), Gaps = 5/155 (3%) Frame = +2 Query: 110 NPKVFFDMTVGGAPAGR-----IVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKG 274 NP V+ D+ G +PA R IV+ELY D VPRT ENFR LCT + +G+PL ++ Sbjct: 12 NPIVYLDLAFGSSPASRPGSNRIVLELYADRVPRTAENFRVLCTNTSKLASTGQPLSFRN 71 Query: 275 SSFHRVIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGS 454 S FHRVIP FM Q ESIYGEKF DE KH P +LSMANAG NTNGS Sbjct: 72 SIFHRVIPKFMIQGGDFTRADGTGGESIYGEKFQDEDLTGKHDVPFLLSMANAGANTNGS 131 Query: 455 QFFICTVPCNWLDGKHVVFGEVVEGMDVVKNIEKV 559 QFFI TVP LDGKHVVFG V++G VV+ +E V Sbjct: 132 QFFITTVPTPHLDGKHVVFGRVLKGKGVVRRVESV 166
>PPIB_RAT (P24368) Peptidyl-prolyl cis-trans isomerase B precursor (EC| 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin B) (S-cyclophilin) (SCYLP) (CYP-S1) Length = 208 Score = 164 bits (416), Expect = 1e-40 Identities = 89/165 (53%), Positives = 105/165 (63%), Gaps = 2/165 (1%) Frame = +2 Query: 116 KVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVI 295 KV+FD +G P GR+ L+ VP+TV+NF AL TGEKG G YK S FHRVI Sbjct: 37 KVYFDFQIGDEPVGRVTFGLFGKTVPKTVDNFVALATGEKGFG-------YKNSKFHRVI 89 Query: 296 PDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFFICTV 475 DFM Q +SIYGE+F DE F KH PG +SMANAG +TNGSQFFI TV Sbjct: 90 KDFMIQGGDFTRGDGTGGKSIYGERFPDENFKLKHYGPGWVSMANAGKDTNGSQFFITTV 149 Query: 476 PCNWLDGKHVVFGEVVEGMDVVKNIE--KVGSRSGICFKQVVIAD 604 +WLDGKHVVFG+V+EGMDVV+ +E K SR K V+I D Sbjct: 150 KTSWLDGKHVVFGKVLEGMDVVRKVENTKTDSRDK-PLKDVIIVD 193
>PPIH_ASPOR (Q2TZ33) Peptidyl-prolyl cis-trans isomerase H (EC 5.2.1.8) (PPIase| H) (Rotamase H) Length = 181 Score = 164 bits (415), Expect = 2e-40 Identities = 84/154 (54%), Positives = 101/154 (65%), Gaps = 1/154 (0%) Frame = +2 Query: 95 ASEMANPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKG 274 +++ NP VFFD+T+GG GRI MEL+ PRT ENFR CTGE G+P YK Sbjct: 8 SAKTPNPVVFFDITLGGESLGRIKMELFTSITPRTAENFRQFCTGESK-SPQGRPQGYKN 66 Query: 275 SSFHRVIPDFMCQXXXXXXXXXXXXESIYGE-KFADEKFVHKHTKPGILSMANAGPNTNG 451 S FHRVI DFM Q +IYG +F DE F+ KH +PG+LSMAN+GPNTNG Sbjct: 67 SKFHRVIKDFMIQGGDFVNGDGTGSRTIYGTPRFQDENFILKHDQPGLLSMANSGPNTNG 126 Query: 452 SQFFICTVPCNWLDGKHVVFGEVVEGMDVVKNIE 553 QFFI T +L+ KHVVFG+VVEGMDVV+ IE Sbjct: 127 CQFFITTTATPFLNNKHVVFGQVVEGMDVVRMIE 160
>PPIB_EMENI (Q5B4R3) Peptidyl-prolyl cis-trans isomerase B precursor (EC| 5.2.1.8) (PPIase B) (Rotamase B) Length = 214 Score = 164 bits (415), Expect = 2e-40 Identities = 89/161 (55%), Positives = 102/161 (63%), Gaps = 4/161 (2%) Frame = +2 Query: 89 IPASEMANPK----VFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGK 256 + ASE PK V+FD+ G GRIV+ LY VP T ENFRAL TGEKG G Sbjct: 22 VNASEPRGPKITNKVYFDIQHGDESLGRIVLGLYGKTVPETAENFRALATGEKGFG---- 77 Query: 257 PLHYKGSSFHRVIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAG 436 Y+GS+FHRVI DFM Q +SIYG KF DE F +HTK G+LSMANAG Sbjct: 78 ---YEGSNFHRVIKDFMIQGGDFTRGDGTGGKSIYGAKFKDENFKLRHTKTGLLSMANAG 134 Query: 437 PNTNGSQFFICTVPCNWLDGKHVVFGEVVEGMDVVKNIEKV 559 +TNGSQFFI T WLDGKHVVFGEV+EG D+V I+ V Sbjct: 135 KDTNGSQFFITTAVTPWLDGKHVVFGEVLEGYDIVDKIQNV 175
>PPIB_MOUSE (P24369) Peptidyl-prolyl cis-trans isomerase B precursor (EC| 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin B) (S-cyclophilin) (SCYLP) (CYP-S1) Length = 208 Score = 164 bits (414), Expect = 2e-40 Identities = 89/165 (53%), Positives = 106/165 (64%), Gaps = 2/165 (1%) Frame = +2 Query: 116 KVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVI 295 KV+FD+ +G GR+V L+ VP+TV+NF AL TGEKG G YK S FHRVI Sbjct: 37 KVYFDLQIGDESVGRVVFGLFGKTVPKTVDNFVALATGEKGFG-------YKNSKFHRVI 89 Query: 296 PDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFFICTV 475 DFM Q +SIYGE+F DE F KH PG +SMANAG +TNGSQFFI TV Sbjct: 90 KDFMIQGGDFTRGDGTGGKSIYGERFPDENFKLKHYGPGWVSMANAGKDTNGSQFFITTV 149 Query: 476 PCNWLDGKHVVFGEVVEGMDVVKNIE--KVGSRSGICFKQVVIAD 604 +WLDGKHVVFG+V+EGMDVV+ +E K SR K V+I D Sbjct: 150 KTSWLDGKHVVFGKVLEGMDVVRKVESTKTDSRDK-PLKDVIIVD 193
>PPIB_HUMAN (P23284) Peptidyl-prolyl cis-trans isomerase B precursor (EC| 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin B) (S-cyclophilin) (SCYLP) (CYP-S1) Length = 208 Score = 162 bits (410), Expect = 7e-40 Identities = 88/165 (53%), Positives = 106/165 (64%), Gaps = 2/165 (1%) Frame = +2 Query: 116 KVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVI 295 KV+FD+ +G GR++ L+ VP+TV+NF AL TGEKG G YK S FHRVI Sbjct: 37 KVYFDLRIGDEDVGRVIFGLFGKTVPKTVDNFVALATGEKGFG-------YKNSKFHRVI 89 Query: 296 PDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFFICTV 475 DFM Q +SIYGE+F DE F KH PG +SMANAG +TNGSQFFI TV Sbjct: 90 KDFMIQGGDFTRGDGTGGKSIYGERFPDENFKLKHYGPGWVSMANAGKDTNGSQFFITTV 149 Query: 476 PCNWLDGKHVVFGEVVEGMDVVKNIE--KVGSRSGICFKQVVIAD 604 WLDGKHVVFG+V+EGM+VV+ +E K SR K V+IAD Sbjct: 150 KTAWLDGKHVVFGKVLEGMEVVRKVESTKTDSRDK-PLKDVIIAD 193
>PPID_CRYNE (Q5KFV5) Peptidyl-prolyl cis-trans isomerase D (EC 5.2.1.8) (PPIase| D) (Rotamase D) Length = 375 Score = 162 bits (409), Expect = 9e-40 Identities = 82/156 (52%), Positives = 99/156 (63%) Frame = +2 Query: 104 MANPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSF 283 M+N +FD+T+ PAGR+ EL+ D VP+T NF+ LC G+K ++G L Y GSSF Sbjct: 1 MSNTIAYFDITIANEPAGRLTFELFDDVVPKTANNFKHLCIGDK-TNEAGVKLAYAGSSF 59 Query: 284 HRVIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFF 463 HR I FM Q ESIYGEKF DE F KH KP +LSMANAGP TNGSQFF Sbjct: 60 HRCIKGFMLQGGDFTRGDGTGGESIYGEKFEDENFELKHDKPMLLSMANAGPGTNGSQFF 119 Query: 464 ICTVPCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRS 571 I TVP LDGKHVVFG V+ +V+ IE + + S Sbjct: 120 ITTVPTPHLDGKHVVFGRVIYNRSLVRRIENIPTTS 155
>PPIB_BOVIN (P80311) Peptidyl-prolyl cis-trans isomerase B precursor (EC| 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin B) (S-cyclophilin) (SCYLP) Length = 208 Score = 158 bits (400), Expect = 1e-38 Identities = 88/165 (53%), Positives = 104/165 (63%), Gaps = 2/165 (1%) Frame = +2 Query: 116 KVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVI 295 KV+FD+ +G GR+V+ L+ VP+TV+NF AL TGEKG G YK S FHRVI Sbjct: 37 KVYFDLRIGDEDIGRVVIGLFGKTVPKTVDNFVALATGEKGFG-------YKDSKFHRVI 89 Query: 296 PDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFFICTV 475 DFM Q +SIYGE+F DE F KH PG +SMANAG +TNGSQFFI TV Sbjct: 90 KDFMIQGGDFTRGDGTGGKSIYGERFPDENFKLKHYGPGWVSMANAGKDTNGSQFFITTV 149 Query: 476 PCNWLDGKHVVFGEVVEGMDVVKNIE--KVGSRSGICFKQVVIAD 604 WLDGKHV FG+V+EGMDVV+ +E K R K V IAD Sbjct: 150 KTAWLDGKHVGFGKVLEGMDVVRKVESTKTDGRDK-PLKDVTIAD 193
>CYP5_CAEEL (P52013) Peptidyl-prolyl cis-trans isomerase 5 precursor (EC| 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin-5) Length = 204 Score = 157 bits (398), Expect = 2e-38 Identities = 87/161 (54%), Positives = 99/161 (61%) Frame = +2 Query: 116 KVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVI 295 KV+FDM +GG P GRIV+ L+ VP+T NF L KG G Y GS FHRVI Sbjct: 30 KVYFDMEIGGKPIGRIVIGLFGKTVPKTATNFIELAKKPKGEG-------YPGSKFHRVI 82 Query: 296 PDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFFICTV 475 DFM Q SIYGEKFADE F KH G LSMANAG +TNGSQFFI TV Sbjct: 83 ADFMIQGGDFTRGDGTGGRSIYGEKFADENFKLKHYGAGWLSMANAGADTNGSQFFITTV 142 Query: 476 PCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRSGICFKQVVI 598 WLDG+HVVFG+++EGMDVV+ IE+ G KQ VI Sbjct: 143 KTPWLDGRHVVFGKILEGMDVVRKIEQTEKLPGDRPKQDVI 183
>PPIB_SCHPO (O94273) Peptidyl-prolyl cis-trans isomerase B precursor (EC| 5.2.1.8) (PPIase B) (Rotamase B) (Cyclophilin 4) Length = 201 Score = 157 bits (396), Expect = 3e-38 Identities = 79/146 (54%), Positives = 95/146 (65%) Frame = +2 Query: 119 VFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVIP 298 V+FD+ G GR+ + L+ VP+T ENFRAL TGEKG G Y+GS FHRVIP Sbjct: 29 VYFDLQQGDEFLGRVTIGLFGKTVPKTAENFRALATGEKGFG-------YEGSIFHRVIP 81 Query: 299 DFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFFICTVP 478 +FM Q +SIYG +F DE F H +PG+LSMANAGP++NGSQFFI TV Sbjct: 82 NFMIQGGDITKGDGTGGKSIYGSRFPDENFKLSHQRPGLLSMANAGPDSNGSQFFITTVK 141 Query: 479 CNWLDGKHVVFGEVVEGMDVVKNIEK 556 WLDG HVVFGEV+ G D+VK I K Sbjct: 142 TPWLDGHHVVFGEVLSGYDIVKKISK 167
>PPIH_SCHPO (O74729) Peptidyl-prolyl cis-trans isomerase cyp3 (EC 5.2.1.8)| (PPIase cyp3) (Rotamase cyp3) Length = 173 Score = 157 bits (396), Expect = 3e-38 Identities = 80/156 (51%), Positives = 102/156 (65%), Gaps = 3/156 (1%) Frame = +2 Query: 113 PKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRV 292 P VF D+ + G GRI + L+ VP+T ENFR CTGE +G + KP+ YK S+FHR+ Sbjct: 5 PVVFMDIAIDGRLLGRIKIRLFSSIVPKTAENFRQFCTGET-LGVNQKPIGYKNSTFHRI 63 Query: 293 IPDFMCQXXXXXXXXXXXXESIYGEK-FADEKFVHKHTKPGILSMANAGPNTNGSQFFIC 469 I FM Q +I+ + F DE F KH +PG+LSMANAG ++NG QFFI Sbjct: 64 IQGFMIQGGDFVSGDGTGSATIFNSRTFPDENFTLKHDRPGLLSMANAGKDSNGCQFFIT 123 Query: 470 TVPCNWLDGKHVVFGEVVEGMDVVKNIEK--VGSRS 571 TVPC++LDGKHVVFGEV+EG D+VK IE VG+ S Sbjct: 124 TVPCDFLDGKHVVFGEVIEGYDIVKEIESTPVGANS 159
>CYP11_CAEEL (P52018) Peptidyl-prolyl cis-trans isomerase 11 (EC 5.2.1.8)| (PPIase) (Rotamase) (Cyclophilin-11) Length = 183 Score = 156 bits (395), Expect = 4e-38 Identities = 82/150 (54%), Positives = 94/150 (62%) Frame = +2 Query: 110 NPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHR 289 NP VF ++T GGAP G IV+EL+ D PRT ENFR CTGE K G P YK +FHR Sbjct: 16 NPIVFLEVTAGGAPIGTIVIELFADVTPRTAENFRQFCTGE--YKKDGVPNGYKNCTFHR 73 Query: 290 VIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFFIC 469 VI DFM Q SIYG KF DE F KH PG+LSMANAG +TNG QFFI Sbjct: 74 VIKDFMIQGGDFCNGDGTGLMSIYGSKFRDENFELKHIGPGMLSMANAGSDTNGCQFFIT 133 Query: 470 TVPCNWLDGKHVVFGEVVEGMDVVKNIEKV 559 ++LD KHVVFG V++GM V+ IE V Sbjct: 134 CAKTDFLDNKHVVFGRVLDGMLTVRKIENV 163
>PPIB_SCHMA (Q26551) Peptidyl-prolyl cis-trans isomerase B precursor (EC| 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin B) (S-cyclophilin) Length = 213 Score = 156 bits (394), Expect = 5e-38 Identities = 80/146 (54%), Positives = 98/146 (67%) Frame = +2 Query: 116 KVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVI 295 KVFFD+ V G P RI++ L+ VP+TVENF+ L G + K G+ YKGS+FHRVI Sbjct: 33 KVFFDIEVDGKPLARIIIGLFGKTVPKTVENFKQLSIGTQL--KDGRTASYKGSTFHRVI 90 Query: 296 PDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFFICTV 475 FM Q SIYG++F DE F +H G LSMANAGP+TNGSQFFI TV Sbjct: 91 KSFMIQGGDFTNHDGTGGFSIYGDRFPDENFKLRHVGAGWLSMANAGPDTNGSQFFITTV 150 Query: 476 PCNWLDGKHVVFGEVVEGMDVVKNIE 553 +WLDGKHVVFG+VVEGM++V+ IE Sbjct: 151 KTSWLDGKHVVFGKVVEGMNIVRQIE 176
>PPIC_HUMAN (P45877) Peptidyl-prolyl cis-trans isomerase C (EC 5.2.1.8)| (PPIase) (Rotamase) (Cyclophilin C) Length = 212 Score = 155 bits (393), Expect = 7e-38 Identities = 83/146 (56%), Positives = 94/146 (64%) Frame = +2 Query: 116 KVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVI 295 KVFFD+ +G GRIV+ L+ VP+TVENF AL TGEKG G YKGS FHRVI Sbjct: 39 KVFFDVRIGDKDVGRIVIGLFGKVVPKTVENFVALATGEKGYG-------YKGSKFHRVI 91 Query: 296 PDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFFICTV 475 DFM Q SIYGE F DE F KH G +SMANAGP+TNGSQFFI Sbjct: 92 KDFMIQGGDITTGDGTGGVSIYGETFPDENFKLKHYGIGWVSMANAGPDTNGSQFFITLT 151 Query: 476 PCNWLDGKHVVFGEVVEGMDVVKNIE 553 WLDGKHVVFG+V++GM VV +IE Sbjct: 152 KPTWLDGKHVVFGKVIDGMTVVHSIE 177
>CYP6_CAEEL (P52014) Peptidyl-prolyl cis-trans isomerase 6 precursor (EC| 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin-6) Length = 201 Score = 155 bits (391), Expect = 1e-37 Identities = 80/153 (52%), Positives = 98/153 (64%) Frame = +2 Query: 116 KVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVI 295 KVFFDM +GG P G+IV+ L+ + VP+TV+NF L +G G Y GS FHRVI Sbjct: 27 KVFFDMEIGGRPVGKIVIGLFGEVVPKTVKNFVELAQRAEGEG-------YVGSKFHRVI 79 Query: 296 PDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFFICTV 475 +FM Q SIYGE+F DE F +H PG LSMANAG +TNGSQFFI T Sbjct: 80 ENFMIQGGDFTRGDGTGGRSIYGERFEDENFKLQHYGPGWLSMANAGEDTNGSQFFITTA 139 Query: 476 PCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRSG 574 +WLDGKHVVFG+++EGMDVV+ IE +G Sbjct: 140 KTSWLDGKHVVFGKILEGMDVVREIEATPKGAG 172
>PPIC_MOUSE (P30412) Peptidyl-prolyl cis-trans isomerase C (EC 5.2.1.8)| (PPIase) (Rotamase) (Cyclophilin C) Length = 212 Score = 155 bits (391), Expect = 1e-37 Identities = 83/146 (56%), Positives = 95/146 (65%) Frame = +2 Query: 116 KVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVI 295 KVFFD+ +G GRIV+ L+ + VP+TVENF AL TGEKG G YKGS FHRVI Sbjct: 39 KVFFDVRIGDKDVGRIVIGLFGNVVPKTVENFVALATGEKGYG-------YKGSIFHRVI 91 Query: 296 PDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFFICTV 475 DFM Q SIYGE F DE F KH G +SMANAGP+TNGSQFFI Sbjct: 92 KDFMIQGGDFTARDGTGGMSIYGETFPDENFKLKHYGIGWVSMANAGPDTNGSQFFITLT 151 Query: 476 PCNWLDGKHVVFGEVVEGMDVVKNIE 553 WLDGKHVVFG+V++GM VV +IE Sbjct: 152 KPTWLDGKHVVFGKVLDGMTVVHSIE 177
>PPIB_SCHJA (Q27774) Peptidyl-prolyl cis-trans isomerase B precursor (EC| 5.2.1.8) (PPIase B) (Rotamase B) (Cyclophilin B) (S-cyclophilin) Length = 213 Score = 155 bits (391), Expect = 1e-37 Identities = 83/152 (54%), Positives = 97/152 (63%) Frame = +2 Query: 116 KVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVI 295 KVFFD+ V P GRI++ L+ VP+TVENF+ L G K G+ YKGS+FHRVI Sbjct: 33 KVFFDIEVDEQPLGRIIIGLFGKTVPKTVENFKQLSIGT--TLKDGRTAAYKGSTFHRVI 90 Query: 296 PDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFFICTV 475 FM Q SIYGE+F DE F KH G LSMANAGPNTNG+QFFI T Sbjct: 91 KSFMIQGGDFTNHDGTGGFSIYGERFPDENFKLKHVGAGWLSMANAGPNTNGAQFFITTT 150 Query: 476 PCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRS 571 WLDGKHVVFG+VVEGM VV+ IE + + S Sbjct: 151 QNPWLDGKHVVFGKVVEGMSVVRQIENMQTDS 182
>CYP8_CAEEL (P52016) Peptidyl-prolyl cis-trans isomerase 8 (EC 5.2.1.8)| (PPIase) (Rotamase) (Cyclophilin-8) Length = 466 Score = 155 bits (391), Expect = 1e-37 Identities = 81/157 (51%), Positives = 97/157 (61%) Frame = +2 Query: 89 IPASEMANPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHY 268 +P N + FFD+++ G PAGRIV L+ PRTVENFRA CTGE G +G Y Sbjct: 1 MPPEVRGNKRAFFDISINGEPAGRIVFSLWNHCCPRTVENFRAFCTGELGK-MNGHYASY 59 Query: 269 KGSSFHRVIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTN 448 +GS FHRVI FM Q SIYG F DE KH KP +LSMAN GP+TN Sbjct: 60 QGSVFHRVIKGFMIQGGDITHGNGTGGYSIYGRTFDDENLALKHKKPYLLSMANRGPDTN 119 Query: 449 GSQFFICTVPCNWLDGKHVVFGEVVEGMDVVKNIEKV 559 GSQFFI + LDGKH VFGEV++G++VVK IE + Sbjct: 120 GSQFFITSEEVPHLDGKHCVFGEVIKGVEVVKAIENL 156
>PPID_SCHPO (Q11004) 40 kDa peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8)| (PPIase) (Rotamase) (Cyclophilin-40) (CYP-40) Length = 356 Score = 153 bits (386), Expect = 4e-37 Identities = 81/161 (50%), Positives = 103/161 (63%) Frame = +2 Query: 122 FFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVIPD 301 +F +++ G I EL+ + VP+TV+NF +LC G + K G+ L YKGS FHRVI + Sbjct: 6 YFKISIDGKIQPTIYFELFDNVVPKTVKNFASLCNGFE---KDGRCLTYKGSRFHRVIKN 62 Query: 302 FMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFFICTVPC 481 FM Q ESIYGEKF DE F KH KP +LSMANAGPNTNGSQFFI TVP Sbjct: 63 FMLQGGDFTRGNGTGGESIYGEKFEDENFELKHDKPFLLSMANAGPNTNGSQFFITTVPT 122 Query: 482 NWLDGKHVVFGEVVEGMDVVKNIEKVGSRSGICFKQVVIAD 604 LDGKHVVFG+V++G V+ IE + +++ VVI + Sbjct: 123 PHLDGKHVVFGKVIQGKSTVRTIENLETKNDDPVVPVVIEE 163
>PPIH_USTMA (Q4P6X6) Peptidyl-prolyl cis-trans isomerase H (EC 5.2.1.8) (PPIase| H) (Rotamase H) (Fragment) Length = 156 Score = 152 bits (383), Expect = 9e-37 Identities = 76/137 (55%), Positives = 90/137 (65%) Frame = +2 Query: 149 PAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVIPDFMCQXXXXX 328 PAGR+ EL+ D VPRT ENFR LCTGE + P YK S FHR+I DFMCQ Sbjct: 2 PAGRLKCELFSDIVPRTSENFRQLCTGE--FRPNHVPEGYKNSIFHRIIKDFMCQGGDFI 59 Query: 329 XXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFFICTVPCNWLDGKHVV 508 SIYG+KF DE F KH K G+LSMAN+GP TNG QFFI PC +LDGKHVV Sbjct: 60 NADGTGSRSIYGDKFDDENFTLKHDKAGLLSMANSGPGTNGCQFFITAQPCPFLDGKHVV 119 Query: 509 FGEVVEGMDVVKNIEKV 559 FG+VV+G+ ++ +E V Sbjct: 120 FGKVVDGLLTLRKMENV 136
>CYPD_YEAST (P35176) Peptidyl-prolyl cis-trans isomerase D precursor (EC| 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin D) Length = 225 Score = 151 bits (382), Expect = 1e-36 Identities = 86/164 (52%), Positives = 102/164 (62%), Gaps = 1/164 (0%) Frame = +2 Query: 116 KVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVI 295 KV+FD+ G GRIVM LY P+TVENF L + + K + Y S FHRVI Sbjct: 35 KVYFDINHGDKQIGRIVMGLYGLTTPQTVENFYQLT-----ISRDPK-MGYLNSIFHRVI 88 Query: 296 PDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFFICTV 475 P+FM Q +SI+G F DE F KH KPG LSMAN G NTNGSQFFI TV Sbjct: 89 PNFMIQGGDFTHRSGIGGKSIFGNTFKDENFDVKHDKPGRLSMANRGKNTNGSQFFITTV 148 Query: 476 PCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRS-GICFKQVVIAD 604 PC WLDGKHVVFGEV++GMDVV IE V + S + K+V+I + Sbjct: 149 PCPWLDGKHVVFGEVLDGMDVVHYIENVKTDSRNMPVKEVIIVE 192
>NKTR_HUMAN (P30414) NK-tumor recognition protein (Natural-killer cells| cyclophilin-related protein) (NK-TR protein) Length = 1462 Score = 151 bits (382), Expect = 1e-36 Identities = 75/150 (50%), Positives = 98/150 (65%), Gaps = 1/150 (0%) Frame = +2 Query: 113 PKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKS-GKPLHYKGSSFHR 289 P+ FD+ + P GRI+ +L+ D P+T +NF LC+GEKG+GK+ GK L YKGS+FHR Sbjct: 7 PQCHFDIEINREPVGRIMFQLFSDICPKTCKNFLCLCSGEKGLGKTTGKKLCYKGSTFHR 66 Query: 290 VIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFFIC 469 V+ +FM Q ESIYG F DE F+ KH + +LSMAN G +TNGSQFFI Sbjct: 67 VVKNFMIQGGDFSEGNGKGGESIYGGYFKDENFILKHDRAFLLSMANRGKHTNGSQFFIT 126 Query: 470 TVPCNWLDGKHVVFGEVVEGMDVVKNIEKV 559 T P LDG HVVFG V+ G +V++ IE + Sbjct: 127 TKPAPHLDGVHVVFGLVISGFEVIEQIENL 156
>NKTR_MOUSE (P30415) NK-tumor recognition protein (Natural-killer cells| cyclophilin-related protein) (NK-TR protein) Length = 1453 Score = 151 bits (382), Expect = 1e-36 Identities = 75/150 (50%), Positives = 98/150 (65%), Gaps = 1/150 (0%) Frame = +2 Query: 113 PKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKS-GKPLHYKGSSFHR 289 P+ FD+ + P GRI+ +L+ D P+T +NF LC+GEKG+GK+ GK L YKGS+FHR Sbjct: 7 PQCHFDIEINREPVGRIMFQLFSDICPKTCKNFLCLCSGEKGLGKTTGKKLCYKGSTFHR 66 Query: 290 VIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFFIC 469 V+ +FM Q ESIYG F DE F+ KH + +LSMAN G +TNGSQFFI Sbjct: 67 VVKNFMIQGGDFSEGNGKGGESIYGGYFKDENFILKHDRAFLLSMANRGKHTNGSQFFIT 126 Query: 470 TVPCNWLDGKHVVFGEVVEGMDVVKNIEKV 559 T P LDG HVVFG V+ G +V++ IE + Sbjct: 127 TKPAPHLDGVHVVFGLVISGFEVIEQIENL 156
>CYP9_CAEEL (Q09637) Peptidyl-prolyl cis-trans isomerase 9 (EC 5.2.1.8)| (PPIase) (Rotamase) (Cyclophilin-9) Length = 309 Score = 140 bits (353), Expect = 3e-33 Identities = 74/152 (48%), Positives = 95/152 (62%), Gaps = 1/152 (0%) Frame = +2 Query: 107 ANPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKP-LHYKGSSF 283 A +VF D++V GRI + L+ + P+T ENFRALCTGE G+ + K LHYK + F Sbjct: 3 AEKRVFLDISVDENLIGRIEIRLFVEDAPKTCENFRALCTGEVGMTPNNKARLHYKQNEF 62 Query: 284 HRVIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFF 463 HR++ FM Q SIYG F DEKF KH++P +LSMAN GPN+N SQFF Sbjct: 63 HRIVKKFMIQGGDITEGDGRGGFSIYGRYFDDEKFKLKHSRPYLLSMANKGPNSNSSQFF 122 Query: 464 ICTVPCNWLDGKHVVFGEVVEGMDVVKNIEKV 559 I T +GKHVVFGEVV+G +VV I+ + Sbjct: 123 ITTAAAPHCNGKHVVFGEVVKGQNVVDYIDNL 154
>PPIA_NEOCA (P84343) Peptidyl-prolyl cis-trans isomerase precursor (EC 5.2.1.8)| (PPIase) (Rotamase) (Cyclophilin) (NcCyP) Length = 178 Score = 139 bits (350), Expect = 6e-33 Identities = 80/164 (48%), Positives = 97/164 (59%), Gaps = 1/164 (0%) Frame = +2 Query: 116 KVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVI 295 K F D+ + G AGRIV+EL D VP+TV+NF +G K YKGS+FHRVI Sbjct: 24 KAFMDIEIDGESAGRIVLELRGDVVPKTVKNF---------IGLFDK---YKGSTFHRVI 71 Query: 296 PDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFFICTV 475 DFM Q SIYG +F DE F KH + G++SMANAGPNTNGSQFFI TV Sbjct: 72 ADFMIQGGDFENHNGTGGHSIYGPRFEDENFTLKHDR-GVISMANAGPNTNGSQFFITTV 130 Query: 476 PCNWLDGKHVVFGEVV-EGMDVVKNIEKVGSRSGICFKQVVIAD 604 WLDG+HVVFG++ + V+ IE +GS G K I D Sbjct: 131 KTEWLDGRHVVFGKITNDSWPTVQAIEALGSSGGRPSKIAKITD 174
>CYPB_YEAST (P23285) Peptidyl-prolyl cis-trans isomerase B precursor (EC| 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin B) (Cyclophilin-related protein) Length = 205 Score = 136 bits (342), Expect = 5e-32 Identities = 77/154 (50%), Positives = 93/154 (60%), Gaps = 1/154 (0%) Frame = +2 Query: 101 EMANPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSS 280 E+ KVFFD+ G GRIV+ LY P+T +NF L T K G + GS+ Sbjct: 32 EVITQKVFFDIEHGEEKVGRIVIGLYGKVCPKTAKNFYKLSTTTNS--KKG----FIGST 85 Query: 281 FHRVIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQF 460 FHRVIP+FM Q +SIYG+ F DE F KH + G LSMAN G +TNGSQF Sbjct: 86 FHRVIPNFMVQGGDFTDGTGVGGKSIYGDTFPDENFTLKHDRKGRLSMANRGKDTNGSQF 145 Query: 461 FICTV-PCNWLDGKHVVFGEVVEGMDVVKNIEKV 559 FI T +WLDGKHVVFG+VV+GMDVV I+ V Sbjct: 146 FITTTEEASWLDGKHVVFGQVVDGMDVVNYIQHV 179
>CYPR_CALVI (P28517) Peptidyl-prolyl cis-trans isomerase, rhodopsin-specific| isozyme precursor (EC 5.2.1.8) (PPIase) (Rotamase) Length = 234 Score = 125 bits (313), Expect = 1e-28 Identities = 66/148 (44%), Positives = 85/148 (57%) Frame = +2 Query: 116 KVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVI 295 K++ D+ P GRIV L+ P+TV NFR +C +G+ + Y GS FHRVI Sbjct: 27 KIYMDVKHQKKPLGRIVFGLFGKRAPKTVTNFRHICL--RGINGTT----YVGSEFHRVI 80 Query: 296 PDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFFICTV 475 F+ Q SIYG+ F DE +H +PG L MAN GP+TNG QF++ TV Sbjct: 81 SRFLIQGGDIVNNDGTGSTSIYGDFFQDEALDVEHLRPGYLGMANRGPDTNGCQFYVTTV 140 Query: 476 PCNWLDGKHVVFGEVVEGMDVVKNIEKV 559 WL+GKH VFG+V+EGMD V IE V Sbjct: 141 AAQWLNGKHTVFGKVIEGMDTVYAIEDV 168
>CYPR_DROME (P15425) Peptidyl-prolyl cis-trans isomerase, rhodopsin-specific| isozyme precursor (EC 5.2.1.8) (PPIase) (Rotamase) Length = 237 Score = 120 bits (300), Expect = 4e-27 Identities = 63/150 (42%), Positives = 84/150 (56%), Gaps = 2/150 (1%) Frame = +2 Query: 116 KVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVI 295 +++ D+ P GRI L+ P+TV NFR +C +G+ + Y GS FHRV+ Sbjct: 28 RIYMDVKHNKKPVGRITFGLFGKLAPKTVANFRHICL--RGINGTS----YVGSRFHRVV 81 Query: 296 PDFMCQXXXXXXXXXXXXESIYGEKFADEK--FVHKHTKPGILSMANAGPNTNGSQFFIC 469 F+ Q SIYG+ F DE +H +PG L MAN GP+TNG QF++ Sbjct: 82 DRFLVQGGDIVNGDGTGSISIYGDYFPDEDKALAVEHNRPGYLGMANRGPDTNGCQFYVT 141 Query: 470 TVPCNWLDGKHVVFGEVVEGMDVVKNIEKV 559 TV WLDGKH VFG+V+EGMD + IE V Sbjct: 142 TVGAKWLDGKHTVFGKVLEGMDTIYAIEDV 171
>PPIL1_SCHPO (P87051) Peptidyl-prolyl cis-trans isomerase ppi1 (EC 5.2.1.8)| (Cyclophilin ppi1) Length = 155 Score = 115 bits (287), Expect = 1e-25 Identities = 65/135 (48%), Positives = 78/135 (57%), Gaps = 3/135 (2%) Frame = +2 Query: 155 GRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVIPDFMCQXXXXXXX 334 G+I++ELY + P+T +NF L K +Y G FHRVIPDF+ Q Sbjct: 11 GKILIELYTEHAPKTCQNFYTLA----------KEGYYDGVIFHRVIPDFVIQGGDPTGT 60 Query: 335 XXXXXESIYGEKFADEKFVHK---HTKPGILSMANAGPNTNGSQFFICTVPCNWLDGKHV 505 SIYG+KF DE +H HT GILSMANAGPNTN SQFFI P WLDGKH Sbjct: 61 GRGGT-SIYGDKFDDE--IHSDLHHTGAGILSMANAGPNTNSSQFFITLAPTPWLDGKHT 117 Query: 506 VFGEVVEGMDVVKNI 550 +FG VV G+ V K + Sbjct: 118 IFGRVVSGLSVCKRM 132
>PPIL1_NEUCR (Q7SF72) Peptidyl-prolyl cis-trans isomerase-like 1 (EC 5.2.1.8)| (PPIase) (Rotamase) Length = 153 Score = 113 bits (283), Expect = 4e-25 Identities = 64/138 (46%), Positives = 80/138 (57%), Gaps = 3/138 (2%) Frame = +2 Query: 155 GRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVIPDFMCQXXXXXXX 334 G +ELY + P+T +NF L ++G +Y + FHR+I DFM Q Sbjct: 2 GTFTLELYTNHAPKTCKNFATLA--DRG--------YYDSTVFHRIIKDFMIQGGDPTGT 51 Query: 335 XXXXXESIYGEKFADEKFVH---KHTKPGILSMANAGPNTNGSQFFICTVPCNWLDGKHV 505 SIYGEKF DE +H KHT G+LSMANAGPNTNGSQFFI P WLDGKH Sbjct: 52 GRGGS-SIYGEKFEDE--IHPGLKHTGAGVLSMANAGPNTNGSQFFITLAPTPWLDGKHT 108 Query: 506 VFGEVVEGMDVVKNIEKV 559 +FG V +GM V++ + V Sbjct: 109 IFGRVKKGMGVIRRMGMV 126
>PPIL1_ASPFU (Q4WCR3) Peptidyl-prolyl cis-trans isomerase-like 1 (EC 5.2.1.8)| (PPIase) (Rotamase) Length = 161 Score = 113 bits (282), Expect = 5e-25 Identities = 67/154 (43%), Positives = 85/154 (55%), Gaps = 3/154 (1%) Frame = +2 Query: 119 VFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVIP 298 V FD ++G +ELY + P+T NF L ++G +Y FHR+IP Sbjct: 5 VVFDTSMGS-----FTVELYNEHAPKTCRNFATLA--QRG--------YYNNVIFHRIIP 49 Query: 299 DFMCQXXXXXXXXXXXXESIYGEKFADEKFVH---KHTKPGILSMANAGPNTNGSQFFIC 469 +FM Q SIYGEKF DE +H KHT G+LSMAN+GPNTNGSQFFI Sbjct: 50 NFMVQTGDPTGTGRGGS-SIYGEKFEDE--IHPGLKHTGAGVLSMANSGPNTNGSQFFIT 106 Query: 470 TVPCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRS 571 P WLDGKH +FG V GM V++ + V + S Sbjct: 107 LAPTPWLDGKHTIFGRVKSGMRVIQRMGLVKTNS 140
>PPIL1_ASPOR (Q2U6U0) Peptidyl-prolyl cis-trans isomerase-like 1 (EC 5.2.1.8)| (PPIase) (Rotamase) Length = 161 Score = 110 bits (275), Expect = 3e-24 Identities = 61/133 (45%), Positives = 76/133 (57%), Gaps = 1/133 (0%) Frame = +2 Query: 155 GRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVIPDFMCQXXXXXXX 334 G +ELY P+T +NF L ++G +Y FHR+IP+FM Q Sbjct: 12 GSFTVELYNSHAPKTCKNFATLA--QRG--------YYNNVIFHRIIPNFMVQTGDPTGT 61 Query: 335 XXXXXESIYGEKFADE-KFVHKHTKPGILSMANAGPNTNGSQFFICTVPCNWLDGKHVVF 511 SIYGEKF DE + KHT GILSMAN+GPNTNGSQFF+ P WLDGKH +F Sbjct: 62 GRGGS-SIYGEKFEDEIRADLKHTGAGILSMANSGPNTNGSQFFVTLAPTPWLDGKHTIF 120 Query: 512 GEVVEGMDVVKNI 550 G V GM V++ + Sbjct: 121 GRVKSGMRVIQRM 133
>PPIL1_EMENI (Q5ASQ0) Peptidyl-prolyl cis-trans isomerase-like 1 (EC 5.2.1.8)| (PPIase) (Rotamase) Length = 162 Score = 110 bits (275), Expect = 3e-24 Identities = 61/133 (45%), Positives = 76/133 (57%), Gaps = 1/133 (0%) Frame = +2 Query: 155 GRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVIPDFMCQXXXXXXX 334 G +ELY P+T +NF L ++G +Y FHR+IP+FM Q Sbjct: 12 GSFTVELYNSHAPKTCKNFATLA--QRG--------YYNNVIFHRIIPNFMVQTGDPTGT 61 Query: 335 XXXXXESIYGEKFADE-KFVHKHTKPGILSMANAGPNTNGSQFFICTVPCNWLDGKHVVF 511 SIYGEKF DE + KHT GILSMAN+GPNTNGSQFFI P WLDGKH +F Sbjct: 62 GRGGS-SIYGEKFEDEIRSDLKHTGAGILSMANSGPNTNGSQFFITLAPTPWLDGKHTIF 120 Query: 512 GEVVEGMDVVKNI 550 G V GM +++ + Sbjct: 121 GRVKSGMRIIQRM 133
>PPIL1_GIBZE (Q4I1Y1) Peptidyl-prolyl cis-trans isomerase-like 1 (EC 5.2.1.8)| (PPIase) (Rotamase) Length = 162 Score = 109 bits (273), Expect = 5e-24 Identities = 64/140 (45%), Positives = 78/140 (55%), Gaps = 3/140 (2%) Frame = +2 Query: 155 GRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVIPDFMCQXXXXXXX 334 G +++ELY P+T NF L +G +Y + FHR+IP+FM Q Sbjct: 12 GSLILELYTTHAPKTCNNFTTLV--RRG--------YYDNTIFHRIIPNFMVQGGDPTGT 61 Query: 335 XXXXXESIYGEKFADEKFVH-KHTKPGILSMANAGPNTNGSQFFICTVPCNWLDGKHVVF 511 SI+GEKF DE KHT GILSMANAGPNTNGSQFF+ P WLDGKH +F Sbjct: 62 GRGGS-SIFGEKFEDEIDPGLKHTGAGILSMANAGPNTNGSQFFVTLAPTPWLDGKHTIF 120 Query: 512 GEVVEGMDVVK--NIEKVGS 565 G V GM +K + K GS Sbjct: 121 GRVKSGMGTIKRMGLVKTGS 140
>PPIL1_HUMAN (Q9Y3C6) Peptidyl-prolyl cis-trans isomerase-like 1 (EC 5.2.1.8)| (PPIase) (Rotamase) Length = 166 Score = 109 bits (272), Expect = 7e-24 Identities = 65/162 (40%), Positives = 87/162 (53%), Gaps = 1/162 (0%) Frame = +2 Query: 89 IPASEMANPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHY 268 IP P V+ + ++G IV+ELY P+T +NF L +G +Y Sbjct: 4 IPPDSWQPPNVYLETSMG-----IIVLELYWKHAPKTCKNFAELA--RRG--------YY 48 Query: 269 KGSSFHRVIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVH-KHTKPGILSMANAGPNT 445 G+ FHR+I DFM Q SIYG++F DE K T GIL+MANAGP+T Sbjct: 49 NGTKFHRIIKDFMIQGGDPTGTGRGGA-SIYGKQFEDELHPDLKFTGAGILAMANAGPDT 107 Query: 446 NGSQFFICTVPCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRS 571 NGSQFF+ P WLDGKH +FG V +G+ +V + V + S Sbjct: 108 NGSQFFVTLAPTQWLDGKHTIFGRVCQGIGMVNRVGMVETNS 149
>PPIL1_MOUSE (Q9D0W5) Peptidyl-prolyl cis-trans isomerase-like 1 (EC 5.2.1.8)| (PPIase) (Rotamase) Length = 166 Score = 108 bits (271), Expect = 9e-24 Identities = 65/162 (40%), Positives = 87/162 (53%), Gaps = 1/162 (0%) Frame = +2 Query: 89 IPASEMANPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHY 268 IP P V+ + ++G IV+ELY P+T +NF L +G +Y Sbjct: 4 IPPDTWQPPNVYLETSMGV-----IVLELYWKHAPKTCKNFAELA--RRG--------YY 48 Query: 269 KGSSFHRVIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVH-KHTKPGILSMANAGPNT 445 G+ FHR+I DFM Q SIYG++F DE K T GIL+MANAGP+T Sbjct: 49 NGTKFHRIIKDFMIQGGDPTGTGRGGA-SIYGKQFEDELHPDLKFTGAGILAMANAGPDT 107 Query: 446 NGSQFFICTVPCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRS 571 NGSQFF+ P WLDGKH +FG V +G+ +V + V + S Sbjct: 108 NGSQFFVTLAPTQWLDGKHTIFGRVCQGIGMVNRVGMVETNS 149
>PPIB_TREPA (O66105) Probable peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8)| (PPIase) (Rotamase) Length = 215 Score = 108 bits (271), Expect = 9e-24 Identities = 67/133 (50%), Positives = 78/133 (58%), Gaps = 1/133 (0%) Frame = +2 Query: 155 GRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVIPDFMCQXXXXXXX 334 G IV+ L+ + P TV NF L G V K G+P Y+G +FHRVI DFM Q Sbjct: 49 GTIVLSLFFEKAPLTVCNFVGLAEGTLAVCK-GRPF-YQGLTFHRVIKDFMIQGGDPQGN 106 Query: 335 XXXXXESIYGEKFADE-KFVHKHTKPGILSMANAGPNTNGSQFFICTVPCNWLDGKHVVF 511 G +F DE +H PG+LSMANAGP TNGSQFFI V WLDGKH VF Sbjct: 107 GTGGP----GYQFPDECDPALRHDSPGVLSMANAGPGTNGSQFFITHVATPWLDGKHTVF 162 Query: 512 GEVVEGMDVVKNI 550 G+VVEGM+VV I Sbjct: 163 GKVVEGMEVVHAI 175
>PPIL1_ASPNG (Q8X191) Peptidyl-prolyl cis-trans isomerase-like 1 (EC 5.2.1.8)| (PPIase) (Rotamase) Length = 162 Score = 108 bits (269), Expect = 2e-23 Identities = 63/140 (45%), Positives = 78/140 (55%), Gaps = 1/140 (0%) Frame = +2 Query: 155 GRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVIPDFMCQXXXXXXX 334 G +ELY P+T +NF L ++G +Y FHR+IP+FM Q Sbjct: 12 GSFTVELYNAHAPKTCKNFATLA--QRG--------YYNNVIFHRIIPNFMVQTGDPTGT 61 Query: 335 XXXXXESIYGEKFADEKFVH-KHTKPGILSMANAGPNTNGSQFFICTVPCNWLDGKHVVF 511 SIYGEKF DE + KHT GILSMAN+GPN NGSQFFI P WLDGKH +F Sbjct: 62 GRGGS-SIYGEKFEDEINPNLKHTGAGILSMANSGPNNNGSQFFITLAPQPWLDGKHTIF 120 Query: 512 GEVVEGMDVVKNIEKVGSRS 571 G V GM V++ + V + S Sbjct: 121 GRVKSGMRVIQRMGLVKTNS 140
>CYP7_YEAST (P47103) Peptidyl-prolyl cis-trans isomerase CYP7 (EC 5.2.1.8)| (PPIase) (Rotamase) Length = 393 Score = 105 bits (261), Expect = 1e-22 Identities = 66/172 (38%), Positives = 89/172 (51%), Gaps = 24/172 (13%) Frame = +2 Query: 110 NPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGE-KGVGKSGKPLHYKGSSFH 286 +P V+ D+++ P GRIV +L+++ P+T ENF LC G+ K K + L YKG+ FH Sbjct: 4 DPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFH 63 Query: 287 RVIPDFMCQXXXXXXXXXXXXES---------IYGEKFA----DEKFVH---------KH 400 RV+ +FM Q S IY +K DE F + + Sbjct: 64 RVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLGEF 123 Query: 401 TKPGILSMANAG-PNTNGSQFFICTVPCNWLDGKHVVFGEVVEGMDVVKNIE 553 +P L MAN G PNTN SQFFI T L+GKH +FG+VV G VV+ IE Sbjct: 124 VEPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIE 175
>PPIL1_CRYNE (Q5KKX7) Peptidyl-prolyl cis-trans isomerase-like 1 (EC 5.2.1.8)| (PPIase) (Rotamase) Length = 174 Score = 105 bits (261), Expect = 1e-22 Identities = 64/150 (42%), Positives = 82/150 (54%), Gaps = 3/150 (2%) Frame = +2 Query: 119 VFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVIP 298 V FD +VG +ELY P+T NF L E+G +Y G FHR+IP Sbjct: 9 VTFDTSVGS-----FTVELYTAHAPKTCNNFAKLA--ERG--------YYNGVIFHRIIP 53 Query: 299 DFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTK---PGILSMANAGPNTNGSQFFIC 469 +FM Q SIYG++FADE +H + GIL+MAN+GPNTNGSQFFI Sbjct: 54 NFMIQGGDPTGTGRGGT-SIYGDRFADE--IHPELRFVGAGILAMANSGPNTNGSQFFIT 110 Query: 470 TVPCNWLDGKHVVFGEVVEGMDVVKNIEKV 559 P +LDGKH +FG V GM ++ +E V Sbjct: 111 CAPTPYLDGKHTIFGRVSSGMKTIQRLEAV 140
>PPIL2_CRYNE (Q5KAW8) Peptidyl-prolyl cis-trans isomerase-like 2 (EC 5.2.1.8)| (PPIase) (Rotamase) (Cyclophilin-60) (Cyclophilin-like protein Cyp-60) Length = 573 Score = 101 bits (252), Expect = 1e-21 Identities = 67/166 (40%), Positives = 83/166 (50%), Gaps = 3/166 (1%) Frame = +2 Query: 86 PIPASEMANPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLH 265 P E K + +T P +EL+ D P+TV NF L K+GK Sbjct: 303 PTKDKERQKSKAYATITTNFGPLN---VELHGDRAPKTVYNFVQLA-------KAGK--- 349 Query: 266 YKGSSFHRVIPDFMCQXXXXXXXXXXXXESIYGEKFADE---KFVHKHTKPGILSMANAG 436 Y FHR+IP FM Q ES +GE F DE K +KH G+LSMAN+G Sbjct: 350 YDNVVFHRLIPGFMVQGGDPTGTGRGG-ESYWGEPFRDEHGEKGAYKHDSRGVLSMANSG 408 Query: 437 PNTNGSQFFICTVPCNWLDGKHVVFGEVVEGMDVVKNIEKVGSRSG 574 P TNGSQFF P LDGKH VFG++V G + + IE+V R G Sbjct: 409 PRTNGSQFFFTFRPTPHLDGKHTVFGKLVGGEETLDKIERVNVRPG 454
>CYPE_DICDI (Q9NI62) Peptidyl-prolyl cis-trans isomerase cypE (EC 5.2.1.8)| (Cyclophilin cypE) Length = 156 Score = 101 bits (251), Expect = 2e-21 Identities = 61/133 (45%), Positives = 74/133 (55%), Gaps = 1/133 (0%) Frame = +2 Query: 155 GRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVIPDFMCQXXXXXXX 334 G I +ELY + P+ +NF L K +Y + FHR+I DFM Q Sbjct: 13 GDITLELYYNHAPKACKNFYEL----------SKRGYYDNTIFHRLIKDFMIQGGDPLGN 62 Query: 335 XXXXXESIYGEKFADEKFVH-KHTKPGILSMANAGPNTNGSQFFICTVPCNWLDGKHVVF 511 ESIYG+KF DE KHT GILSMAN+G N+NGSQFFI P WLDGKH +F Sbjct: 63 GRGG-ESIYGKKFEDEITKELKHTGAGILSMANSGVNSNGSQFFITFGPTPWLDGKHTIF 121 Query: 512 GEVVEGMDVVKNI 550 G V GM VV+ + Sbjct: 122 GRVKSGMKVVQKM 134
>CYP4_CAEEL (P52012) Peptidyl-prolyl cis-trans isomerase 4 (EC 5.2.1.8)| (PPIase) (Rotamase) (Cyclophilin-4) (Cyclophilin mog-6) (Masculinisation of germline protein 6) Length = 523 Score = 95.9 bits (237), Expect = 8e-20 Identities = 56/142 (39%), Positives = 76/142 (53%), Gaps = 2/142 (1%) Frame = +2 Query: 155 GRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVIPDFMCQXXXXXXX 334 G + +EL+ VP+ ENF C+ +Y + FHR+I +FM Q Sbjct: 289 GPLNLELFAPKVPKACENFITHCSNG----------YYNNTKFHRLIKNFMLQGGDPTGT 338 Query: 335 XXXXXESIYGEKFADEKFVH--KHTKPGILSMANAGPNTNGSQFFICTVPCNWLDGKHVV 508 ESI+ + F+DE F+ H G+LSMAN G NTNGSQFFI PC +LD KH + Sbjct: 339 GHGG-ESIWDKPFSDE-FISGFSHDARGVLSMANKGSNTNGSQFFITFRPCKYLDRKHTI 396 Query: 509 FGEVVEGMDVVKNIEKVGSRSG 574 FG +V G D + IEK+ + G Sbjct: 397 FGRLVGGQDTLTTIEKLETEEG 418
>PPIL2_MOUSE (Q9D787) Peptidyl-prolyl cis-trans isomerase-like 2 (EC 5.2.1.8)| (PPIase) (Rotamase) (Cyclophilin-60) (Cyclophilin-like protein Cyp-60) Length = 521 Score = 95.5 bits (236), Expect = 1e-19 Identities = 58/138 (42%), Positives = 75/138 (54%), Gaps = 1/138 (0%) Frame = +2 Query: 155 GRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVIPDFMCQXXXXXXX 334 G + +EL+ D P+T ENF LC K +Y G+ FHR I +F+ Q Sbjct: 289 GDLNLELHCDLTPKTCENFIKLC----------KKQYYDGTIFHRSIRNFVIQGGDPTGT 338 Query: 335 XXXXXESIYGEKFADEKFVH-KHTKPGILSMANAGPNTNGSQFFICTVPCNWLDGKHVVF 511 ES +G+ F DE + HT G+LSMAN+GPNTN SQFFI C +LD KH +F Sbjct: 339 GTGG-ESFWGKPFKDEFRPNLSHTGRGVLSMANSGPNTNKSQFFITFRSCAYLDKKHTIF 397 Query: 512 GEVVEGMDVVKNIEKVGS 565 G VV G D + +E V S Sbjct: 398 GRVVGGFDTLTAMENVES 415
>PPIL2_HUMAN (Q13356) Peptidyl-prolyl cis-trans isomerase-like 2 (EC 5.2.1.8)| (PPIase) (Rotamase) (Cyclophilin-60) (Cyclophilin-like protein Cyp-60) Length = 520 Score = 95.1 bits (235), Expect = 1e-19 Identities = 59/138 (42%), Positives = 76/138 (55%), Gaps = 1/138 (0%) Frame = +2 Query: 155 GRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVIPDFMCQXXXXXXX 334 G + +EL+ D P+T ENF LC K +Y G+ FHR I +F+ Q Sbjct: 289 GDLNLELHCDLTPKTCENFIRLC----------KKHYYDGTIFHRSIRNFVIQGGDPTGT 338 Query: 335 XXXXXESIYGEKFADEKFVH-KHTKPGILSMANAGPNTNGSQFFICTVPCNWLDGKHVVF 511 ES +G+ F DE + HT GILSMAN+GPN+N SQFFI C +LD KH +F Sbjct: 339 GTGG-ESYWGKPFKDEFRPNLSHTGRGILSMANSGPNSNRSQFFITFRSCAYLDKKHTIF 397 Query: 512 GEVVEGMDVVKNIEKVGS 565 G VV G DV+ +E V S Sbjct: 398 GRVVGGFDVLTAMENVES 415
>PPIL3_CHICK (Q5ZLV2) Peptidyl-prolyl cis-trans isomerase-like 3 (EC 5.2.1.8)| (PPIase) (Rotamase) (Cyclophilin-like protein PPIL3) Length = 161 Score = 94.0 bits (232), Expect = 3e-19 Identities = 56/136 (41%), Positives = 76/136 (55%), Gaps = 1/136 (0%) Frame = +2 Query: 155 GRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVIPDFMCQXXXXXXX 334 G I +EL+ + P+T ENF ALC +Y G FHR I FM Q Sbjct: 10 GDIKIELFCERTPKTCENFLALCASN----------YYNGCVFHRNIKGFMVQTGDPLGT 59 Query: 335 XXXXXESIYGEKFADEKFVH-KHTKPGILSMANAGPNTNGSQFFICTVPCNWLDGKHVVF 511 SI+G+KF DE + KH+ G++SMAN GPNTNGSQFFI LD K+ VF Sbjct: 60 GKGGT-SIWGKKFEDEFSEYLKHSVRGVVSMANNGPNTNGSQFFITYGKQPHLDMKYTVF 118 Query: 512 GEVVEGMDVVKNIEKV 559 G+V++G++ + +EK+ Sbjct: 119 GKVIDGLETLDELEKL 134
>PPIL3_RAT (Q812D3) Peptidyl-prolyl cis-trans isomerase-like 3 (EC 5.2.1.8)| (PPIase) (Rotamase) (Cyclophilin-like protein PPIL3) (CYP10L) Length = 161 Score = 93.2 bits (230), Expect = 5e-19 Identities = 55/136 (40%), Positives = 75/136 (55%), Gaps = 1/136 (0%) Frame = +2 Query: 155 GRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVIPDFMCQXXXXXXX 334 G I +E++ + P+T ENF ALC +Y G FHR I FM Q Sbjct: 10 GDIKIEVFCERTPKTCENFLALCASN----------YYNGCVFHRNIKGFMVQTGDPTGT 59 Query: 335 XXXXXESIYGEKFADEKFVH-KHTKPGILSMANAGPNTNGSQFFICTVPCNWLDGKHVVF 511 SI+G+KF DE + KH G++SMAN GPNTNGSQFFI LD K+ VF Sbjct: 60 GRGGS-SIWGKKFEDEYSEYLKHNVRGVVSMANNGPNTNGSQFFITYGKQPHLDMKYTVF 118 Query: 512 GEVVEGMDVVKNIEKV 559 G+V++G++ + +EK+ Sbjct: 119 GKVIDGLETLDELEKL 134
>PPIL3_HUMAN (Q9H2H8) Peptidyl-prolyl cis-trans isomerase-like 3 (EC 5.2.1.8)| (PPIase) (Rotamase) (Cyclophilin-like protein PPIL3) (Cyclophilin J) (CyPJ) Length = 161 Score = 93.2 bits (230), Expect = 5e-19 Identities = 55/136 (40%), Positives = 75/136 (55%), Gaps = 1/136 (0%) Frame = +2 Query: 155 GRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVIPDFMCQXXXXXXX 334 G I +E++ + P+T ENF ALC +Y G FHR I FM Q Sbjct: 10 GDIKIEVFCERTPKTCENFLALCASN----------YYNGCIFHRNIKGFMVQTGDPTGT 59 Query: 335 XXXXXESIYGEKFADEKFVH-KHTKPGILSMANAGPNTNGSQFFICTVPCNWLDGKHVVF 511 SI+G+KF DE + KH G++SMAN GPNTNGSQFFI LD K+ VF Sbjct: 60 GRGG-NSIWGKKFEDEYSEYLKHNVRGVVSMANNGPNTNGSQFFITYGKQPHLDMKYTVF 118 Query: 512 GEVVEGMDVVKNIEKV 559 G+V++G++ + +EK+ Sbjct: 119 GKVIDGLETLDELEKL 134
>PPIL3_CRYNE (Q5KHA8) Peptidyl-prolyl cis-trans isomerase-like 3 (EC 5.2.1.8)| (PPIase) (Rotamase) Length = 167 Score = 91.3 bits (225), Expect = 2e-18 Identities = 56/135 (41%), Positives = 80/135 (59%), Gaps = 1/135 (0%) Frame = +2 Query: 155 GRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVIPDFMCQXXXXXXX 334 G I +EL+ ++VPRT ENF ALC SG+ Y G+ FHR I FM Q Sbjct: 10 GDIKIELFCESVPRTAENFLALCA-------SGQ---YDGTLFHRNIRGFMIQGGDPTGT 59 Query: 335 XXXXXESIYGEKFADE-KFVHKHTKPGILSMANAGPNTNGSQFFICTVPCNWLDGKHVVF 511 +SI+G F+DE + + G+++MANAGP+TN SQFFI LDGK+ +F Sbjct: 60 GKGG-QSIWGRPFSDEIRQTLRFNNRGMVAMANAGPDTNKSQFFITYAKQPSLDGKYSIF 118 Query: 512 GEVVEGMDVVKNIEK 556 G+V++GM+ + ++EK Sbjct: 119 GKVIDGMETLDSMEK 133
>PPIL3_MOUSE (Q9D6L8) Peptidyl-prolyl cis-trans isomerase-like 3 (EC 5.2.1.8)| (PPIase) (Rotamase) (Cyclophilin-like protein PPIL3) (CYP10L) Length = 161 Score = 90.9 bits (224), Expect = 3e-18 Identities = 54/136 (39%), Positives = 74/136 (54%), Gaps = 1/136 (0%) Frame = +2 Query: 155 GRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVIPDFMCQXXXXXXX 334 G I +E++ + P+T ENF ALC +Y G FHR I FM Q Sbjct: 10 GDIKIEVFCERTPKTCENFLALCASN----------YYNGCVFHRNIKGFMVQTGDPTGT 59 Query: 335 XXXXXESIYGEKFADEKFVH-KHTKPGILSMANAGPNTNGSQFFICTVPCNWLDGKHVVF 511 SI+ +KF DE + KH G++SMAN GPNTNGSQFFI LD K+ VF Sbjct: 60 GRGGS-SIWAKKFEDEYSEYLKHNVRGVVSMANNGPNTNGSQFFITYGKQPHLDMKYTVF 118 Query: 512 GEVVEGMDVVKNIEKV 559 G+V++G++ + +EK+ Sbjct: 119 GKVIDGLETLDELEKL 134
>CYP10_CAEEL (P52017) Peptidyl-prolyl cis-trans isomerase 10 (EC 5.2.1.8)| (PPIase) (Rotamase) (Cyclophilin-10) Length = 161 Score = 90.9 bits (224), Expect = 3e-18 Identities = 57/138 (41%), Positives = 74/138 (53%), Gaps = 2/138 (1%) Frame = +2 Query: 152 AGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVIPDFMCQXXXXXX 331 +G I +ELY D P+ ENF ALC + +Y G FHR I DFM Q Sbjct: 9 SGDIKIELYVDDAPKACENFLALCASD----------YYNGCIFHRNIKDFMVQTGDPTH 58 Query: 332 XXXXXXESIYGEKFADEKFVH--KHTKPGILSMANAGPNTNGSQFFICTVPCNWLDGKHV 505 ESI+G F DE FV KH G +SMAN GP++N SQFFI LD K+ Sbjct: 59 SGKGG-ESIWGGPFEDE-FVSALKHDSRGCVSMANNGPDSNRSQFFITYAKQAHLDMKYT 116 Query: 506 VFGEVVEGMDVVKNIEKV 559 +FG+V++G D ++ IE + Sbjct: 117 LFGKVIDGFDTLEEIETI 134
>PPIL2_SCHPO (Q09928) Peptidyl-prolyl cis-trans isomerase cyp8 (EC 5.2.1.8)| (PPIase cyp8) (Rotamase cyp8) Length = 508 Score = 90.1 bits (222), Expect = 4e-18 Identities = 59/141 (41%), Positives = 75/141 (53%), Gaps = 2/141 (1%) Frame = +2 Query: 155 GRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVIPDFMCQXXXXXXX 334 G I +EL+ D P V NF L K +Y+ + FHR I FM Q Sbjct: 277 GEINIELHTDYAPHAVYNFVQLA----------KQGYYRNTIFHRNIARFMIQGGDPSGT 326 Query: 335 XXXXXESIYGEKFADEKFVH--KHTKPGILSMANAGPNTNGSQFFICTVPCNWLDGKHVV 508 +SI+G+ F DE F + KH GI+SMAN G NTNGSQFFI P LD KH + Sbjct: 327 GRGG-QSIWGKPFKDE-FCNPLKHDDRGIISMANRGKNTNGSQFFILYGPAKHLDNKHTI 384 Query: 509 FGEVVEGMDVVKNIEKVGSRS 571 FG VV G++V+ +EKV + S Sbjct: 385 FGRVVGGLNVLDALEKVPTNS 405
>PPIL3_NEUCR (Q6MWS8) Peptidyl-prolyl cis-trans isomerase-like 3 (EC 5.2.1.8)| (PPIase) (Rotamase) Length = 167 Score = 90.1 bits (222), Expect = 4e-18 Identities = 57/140 (40%), Positives = 77/140 (55%), Gaps = 7/140 (5%) Frame = +2 Query: 155 GRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVIPDFMCQXXXXXXX 334 G + +E++ ++VP+T ENF ALC SG +Y S FHR+IP FM Q Sbjct: 10 GDLKIEIFCESVPKTAENFLALCA-------SG---YYNASPFHRMIPSFMVQTGAPANP 59 Query: 335 XX----XXXESIYGEKFADE-KFVHKHTKPGILSMANAGPNTNGSQFFICTVPCNWLDGK 499 SIYG F DE + V +H + GI+SMAN GPNTNGSQFFI LDG Sbjct: 60 SPPENPKGGRSIYGPTFEDEIRPVLRHNERGIVSMANKGPNTNGSQFFILFDKAPHLDGL 119 Query: 500 HVVFGEVV--EGMDVVKNIE 553 + VFG+++ E + + +E Sbjct: 120 NTVFGKLIGDESLQTLAKLE 139
>PPIL3_GIBZE (Q4IPB8) Peptidyl-prolyl cis-trans isomerase-like 3 (EC 5.2.1.8)| (PPIase) (Rotamase) Length = 167 Score = 89.0 bits (219), Expect = 1e-17 Identities = 60/142 (42%), Positives = 75/142 (52%), Gaps = 7/142 (4%) Frame = +2 Query: 155 GRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVIPDFMCQXXXXXX- 331 G I +E+Y ++VP+T ENF ALC G G +Y S FHRVIP FM Q Sbjct: 10 GDIKVEIYCESVPKTAENFLALC----GSG------YYDKSPFHRVIPKFMAQTGAPATP 59 Query: 332 ---XXXXXXESIYGEKFADE-KFVHKHTKPGILSMANAGPNTNGSQFFICTVPCNWLDGK 499 SI+G F DE + +H G+LSMAN GP TNGSQFFI LDG Sbjct: 60 NPPENPKGGRSIWGGAFEDEIRPALRHGARGVLSMANKGPGTNGSQFFITFDKAPHLDGL 119 Query: 500 HVVFGEVV--EGMDVVKNIEKV 559 + VFG V+ EG+ + +E V Sbjct: 120 NTVFGRVIGDEGLATLAKMEAV 141
>PPIB_STRCH (P77949) Peptidyl-prolyl cis-trans isomerase B (EC 5.2.1.8) (PPIase| B) (Rotamase B) (Cyclophilin ScCypB) (S-cyclophilin) Length = 175 Score = 87.0 bits (214), Expect = 4e-17 Identities = 54/128 (42%), Positives = 66/128 (51%), Gaps = 6/128 (4%) Frame = +2 Query: 155 GRIVMELYKDAVPRTVENFRALCTGEKG-----VGKSGKPLHYKGSSFHRVIPDFMCQXX 319 G I + L + P+TV NF L TG++ G+ Y G+ FHRVI FM Q Sbjct: 14 GDIEIRLLPNHAPKTVRNFVELATGQREWVNPETGEKSTDRLYDGTVFHRVISGFMIQGG 73 Query: 320 XXXXXXXXXXESIYGEKFADEKFVHK-HTKPGILSMANAGPNTNGSQFFICTVPCNWLDG 496 G KFADE T+P +L+MANAGP TNGSQFF+ P WL G Sbjct: 74 DPLGNGTGGP----GYKFADEFHPELGFTQPYLLAMANAGPGTNGSQFFLTVSPTAWLTG 129 Query: 497 KHVVFGEV 520 KH +FGEV Sbjct: 130 KHTIFGEV 137
>PPIL2_GIBZE (Q4IBK5) Peptidyl-prolyl cis-trans isomerase-like 2 (EC 5.2.1.8)| (PPIase) (Rotamase) (Cyclophilin-60) (Cyclophilin-like protein Cyp-60) Length = 588 Score = 85.5 bits (210), Expect = 1e-16 Identities = 56/137 (40%), Positives = 72/137 (52%), Gaps = 2/137 (1%) Frame = +2 Query: 155 GRIVMELYKDAVPRTVENFRALC-TGEKGVGKSGKPLHYKGSSFHRVIPDFMCQXXXXXX 331 G + +ELY + P+ V NF L TG +YKG +FHR IP+FM Q Sbjct: 332 GDLTIELYPEFAPKAVWNFIKLSQTG-----------YYKGVAFHRNIPNFMIQGGDPSG 380 Query: 332 XXXXXXESIYGEKFADE-KFVHKHTKPGILSMANAGPNTNGSQFFICTVPCNWLDGKHVV 508 +S++G+ F DE H G LSMAN G NTN SQFF P LD KH V Sbjct: 381 SGRGG-QSVWGKYFDDEFDGPMTHNGRGTLSMANKGKNTNSSQFFFAYKPTPHLDRKHTV 439 Query: 509 FGEVVEGMDVVKNIEKV 559 FG+VVE ++V+ +E V Sbjct: 440 FGKVVENINVLSKMENV 456
>PPIL2_NEUCR (Q7RXA6) Peptidyl-prolyl cis-trans isomerase-like 2 (EC 5.2.1.8)| (PPIase) (Rotamase) (Cyclophilin-60) (Cyclophilin-like protein Cyp-60) Length = 597 Score = 81.6 bits (200), Expect = 2e-15 Identities = 57/155 (36%), Positives = 81/155 (52%), Gaps = 5/155 (3%) Frame = +2 Query: 155 GRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVIPDFMCQXXXXXXX 334 G + +EL + P+ V NF L EKG +Y+ +FHR I +FM Q Sbjct: 339 GPLTLELLPEFAPKAVWNFLRL--SEKG--------YYRDVAFHRSIRNFMIQGGDPSGT 388 Query: 335 XXXXXESIYGEKFADE-KFVHKHTKPGILSMANAGPNTNGSQFFICTVPCNWLDGKHVVF 511 SI+G+ F DE + + H+ GI+SMAN G NTN SQFFI P + LD KH +F Sbjct: 389 GRGGS-SIWGKNFEDEFEGPNTHSARGIVSMANKGKNTNSSQFFITYRPASHLDRKHTIF 447 Query: 512 GEVVEGMD----VVKNIEKVGSRSGICFKQVVIAD 604 +V+EG D ++N+ GS + ++VI D Sbjct: 448 AKVIEGQDTTLTAMENVATDGSDRPL--NKIVIKD 480
>CYPR_YEAST (P25334) Peptidyl-prolyl cis-trans isomerase CPR4 precursor (EC| 5.2.1.8) (PPIase) (Rotamase) Length = 318 Score = 79.3 bits (194), Expect = 8e-15 Identities = 52/145 (35%), Positives = 71/145 (48%), Gaps = 7/145 (4%) Frame = +2 Query: 122 FFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGV--GKSGKPLH---YKGSSFH 286 +FD + ELY VP+TV NF L G K V GK +H Y+ + + Sbjct: 55 YFDPVSKSMKEADLTFELYGTVVPKTVNNFAMLAHGVKAVIEGKDPNDIHTYSYRKTKIN 114 Query: 287 RVIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFFI 466 +V P+ Q ++YG KF DE F KH +P L+MA GP++N S+F I Sbjct: 115 KVYPNKYIQGGVVAPDVGPF--TVYGPKFDDENFYLKHDRPERLAMAYFGPDSNTSEFII 172 Query: 467 CTVP--CNWLDGKHVVFGEVVEGMD 535 T LDGK VVFG++ G+D Sbjct: 173 TTKADGNEELDGKSVVFGQITSGLD 197
>PPIA_MYCTU (P65762) Probable peptidyl-prolyl cis-trans isomerase A (EC| 5.2.1.8) (PPIase A) (Rotamase A) Length = 182 Score = 79.0 bits (193), Expect = 1e-14 Identities = 58/145 (40%), Positives = 72/145 (49%), Gaps = 8/145 (5%) Frame = +2 Query: 155 GRIVMELYKDAVPRTVENFRALCTGEKGVGK---SGKPL--HYKGSSFHRVIPDFMCQXX 319 G I + L+ + P+TV NF L G K SG P Y G+ FHRVI FM Q Sbjct: 24 GDIKIALFGNHAPKTVANFVGLAQGTKDYSTQNASGGPSGPFYDGAVFHRVIQGFMIQGG 83 Query: 320 XXXXXXXXXXESIYGEKFADEKFVH-KHTKPGILSMANAGPNTNGSQFFICTVPCNWLDG 496 G KFADE + KP +L+MANAGP TNGSQFFI L+ Sbjct: 84 DPTGTGRGGP----GYKFADEFHPELQFDKPYLLAMANAGPGTNGSQFFITVGKTPHLNR 139 Query: 497 KHVVFGEVV--EGMDVVKNIEKVGS 565 +H +FGEV+ E VV+ I K + Sbjct: 140 RHTIFGEVIDAESQRVVEAISKTAT 164
>PPIA_MYCBO (P65763) Probable peptidyl-prolyl cis-trans isomerase A (EC| 5.2.1.8) (PPIase A) (Rotamase A) Length = 182 Score = 79.0 bits (193), Expect = 1e-14 Identities = 58/145 (40%), Positives = 72/145 (49%), Gaps = 8/145 (5%) Frame = +2 Query: 155 GRIVMELYKDAVPRTVENFRALCTGEKGVGK---SGKPL--HYKGSSFHRVIPDFMCQXX 319 G I + L+ + P+TV NF L G K SG P Y G+ FHRVI FM Q Sbjct: 24 GDIKIALFGNHAPKTVANFVGLAQGTKDYSTQNASGGPSGPFYDGAVFHRVIQGFMIQGG 83 Query: 320 XXXXXXXXXXESIYGEKFADEKFVH-KHTKPGILSMANAGPNTNGSQFFICTVPCNWLDG 496 G KFADE + KP +L+MANAGP TNGSQFFI L+ Sbjct: 84 DPTGTGRGGP----GYKFADEFHPELQFDKPYLLAMANAGPGTNGSQFFITVGKTPHLNR 139 Query: 497 KHVVFGEVV--EGMDVVKNIEKVGS 565 +H +FGEV+ E VV+ I K + Sbjct: 140 RHTIFGEVIDAESQRVVEAISKTAT 164
>PPIA_MYCLE (Q9CDE9) Probable peptidyl-prolyl cis-trans isomerase A (EC| 5.2.1.8) (PPIase A) (Rotamase A) Length = 182 Score = 77.0 bits (188), Expect = 4e-14 Identities = 54/130 (41%), Positives = 66/130 (50%), Gaps = 6/130 (4%) Frame = +2 Query: 155 GRIVMELYKDAVPRTVENFRALCTGEKGVGK---SGKPL--HYKGSSFHRVIPDFMCQXX 319 G I + L+ + VP+TV NF L G K SG P Y G+ FHRVI FM Q Sbjct: 24 GDIKVALFGNHVPKTVANFVGLAQGTKEYSTQNASGGPSGPFYDGAVFHRVIQGFMIQGG 83 Query: 320 XXXXXXXXXXESIYGEKFADEKFVH-KHTKPGILSMANAGPNTNGSQFFICTVPCNWLDG 496 G KFADE + KP +L+MANAGP TNGSQFFI L+ Sbjct: 84 DPTGTGRGGP----GYKFADEFHPELQFDKPYLLAMANAGPGTNGSQFFITVGETPHLNR 139 Query: 497 KHVVFGEVVE 526 +H +FGEV + Sbjct: 140 RHTIFGEVTD 149
>PPIL4_MOUSE (Q9CXG3) Peptidyl-prolyl cis-trans isomerase-like 4 (EC 5.2.1.8)| (PPIase) (Rotamase) (Cyclophilin-like protein PPIL4) Length = 492 Score = 77.0 bits (188), Expect = 4e-14 Identities = 52/143 (36%), Positives = 69/143 (48%), Gaps = 9/143 (6%) Frame = +2 Query: 155 GRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVIPDFMCQXXXXXXX 334 G +V++LY + PR NF LC K +Y H V DF+ Q Sbjct: 10 GDVVIDLYTEERPRACLNFLKLC----------KIKYYNYCLIHNVQRDFIIQTGDPTGT 59 Query: 335 XXXXXESIYGEKFADEKFVH--------KHTKPGILSMANAGPNTNGSQFFICTVP-CNW 487 ESI+G+ + D+ KH K G +SM N G + +GSQF I T ++ Sbjct: 60 GRGG-ESIFGQLYGDQASFFEAEKVPRIKHKKKGTVSMVNNGSDQHGSQFLITTGENLDY 118 Query: 488 LDGKHVVFGEVVEGMDVVKNIEK 556 LDG H VFGEV EGMD+VK I + Sbjct: 119 LDGVHTVFGEVTEGMDIVKKINE 141
>PPIL4_HUMAN (Q8WUA2) Peptidyl-prolyl cis-trans isomerase-like 4 (EC 5.2.1.8)| (PPIase) (Rotamase) (Cyclophilin-like protein PPIL4) Length = 492 Score = 76.6 bits (187), Expect = 5e-14 Identities = 51/143 (35%), Positives = 69/143 (48%), Gaps = 9/143 (6%) Frame = +2 Query: 155 GRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVIPDFMCQXXXXXXX 334 G +V++LY + PR NF LC K +Y H V DF+ Q Sbjct: 10 GDVVIDLYTEERPRACLNFLKLC----------KIKYYNYCLIHNVQRDFIIQTGDPTGT 59 Query: 335 XXXXXESIYGEKFADEKFVH--------KHTKPGILSMANAGPNTNGSQFFICTVP-CNW 487 ESI+G+ + D+ KH K G +SM N G + +GSQF I T ++ Sbjct: 60 GRGG-ESIFGQLYGDQASFFEAEKVPRIKHKKKGTVSMVNNGSDQHGSQFLITTGENLDY 118 Query: 488 LDGKHVVFGEVVEGMDVVKNIEK 556 LDG H VFGEV EGMD++K I + Sbjct: 119 LDGVHTVFGEVTEGMDIIKKINE 141
>PPIL2_USTMA (Q4P555) Peptidyl-prolyl cis-trans isomerase-like 2 (EC 5.2.1.8)| (PPIase) (Rotamase) (Cyclophilin-60) (Cyclophilin-like protein Cyp-60) Length = 582 Score = 76.3 bits (186), Expect = 7e-14 Identities = 56/145 (38%), Positives = 69/145 (47%), Gaps = 5/145 (3%) Frame = +2 Query: 155 GRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVIPDFMCQXXXXXXX 334 G + +EL+ P+T NF LC K GK Y + FHR IP FM Q Sbjct: 302 GALNLELHCGKAPKTCFNFLQLC-------KHGK---YDDTLFHRNIPGFMIQGGDPTGT 351 Query: 335 XXXXXESIYGEKFADE---KFVHKHTKPGILSMANAGPNTNGSQFFICTVPCNWLDGKHV 505 SI+ F DE KH G+LSMAN G +TN SQFFI LDGKH Sbjct: 352 GRGGS-SIWNSNFRDEFNEPGAFKHDTRGVLSMANKGKDTNASQFFITYRGVPHLDGKHT 410 Query: 506 VFGEVVEGMD--VVKNIEKVGSRSG 574 VFG +V+G + +E+V S G Sbjct: 411 VFGRLVDGDKDATLTKMEQVPSEQG 435
>PPIB_BACSU (P35137) Peptidyl-prolyl cis-trans isomerase B (EC 5.2.1.8) (PPIase| B) (Rotamase B) Length = 143 Score = 74.3 bits (181), Expect = 3e-13 Identities = 51/131 (38%), Positives = 63/131 (48%) Frame = +2 Query: 158 RIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVIPDFMCQXXXXXXXX 337 +I ELY +A P TV NF L Y G +FHRVIP F+ Q Sbjct: 13 KIEFELYPEAAPGTVANFEKLANEG----------FYDGLTFHRVIPGFVSQGGCPHGTG 62 Query: 338 XXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFFICTVPCNWLDGKHVVFGE 517 Y K E H H + G LSMA+AG +T GSQFFI P L+G H VFG+ Sbjct: 63 TGGPG--YTIKCETEGNPHTH-EAGALSMAHAGKDTGGSQFFIVHEPQPHLNGVHTVFGK 119 Query: 518 VVEGMDVVKNI 550 V G++ KN+ Sbjct: 120 VTSGLEFAKNM 130
>PPIL3_USTMA (Q4PCH8) Peptidyl-prolyl cis-trans isomerase-like 3 (EC 5.2.1.8)| (PPIase) (Rotamase) Length = 168 Score = 73.9 bits (180), Expect = 3e-13 Identities = 47/128 (36%), Positives = 65/128 (50%), Gaps = 1/128 (0%) Frame = +2 Query: 155 GRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVIPDFMCQXXXXXXX 334 G I +E++ DA PR ENF C Y +HR I FM Q Sbjct: 10 GDIKVEVFCDATPRAAENFLGHCAAGT----------YNDVKWHRNIKSFMIQTGDPTGT 59 Query: 335 XXXXXESIYGEKFADE-KFVHKHTKPGILSMANAGPNTNGSQFFICTVPCNWLDGKHVVF 511 +SI+G+ FADE + K + GI++ ANAGP+TN SQFFI LDGK+ + Sbjct: 60 GKGG-QSIWGKPFADEIRSSLKFDRRGIVACANAGPDTNKSQFFITYAKQPHLDGKYTII 118 Query: 512 GEVVEGMD 535 G+V++G + Sbjct: 119 GKVIDGAE 126
>CWC27_CRYNE (Q5KAB3) Peptidyl-prolyl isomerase CWC27 (EC 5.2.1.8)| Length = 491 Score = 71.6 bits (174), Expect = 2e-12 Identities = 56/156 (35%), Positives = 74/156 (47%), Gaps = 4/156 (2%) Frame = +2 Query: 110 NPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHR 289 N KV D T AG I +EL+ P+ V NF AL +Y G FHR Sbjct: 12 NGKVIIDTT-----AGEIEVELWGKECPKAVRNFLALTMEG----------YYDGVIFHR 56 Query: 290 VIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVH---KHTKPGILSMANAGP-NTNGSQ 457 V+P F+ Q ES YGE F DE +H K + G+L MAN G N+N SQ Sbjct: 57 VVPGFIIQSGDPTGTGMGG-ESFYGEPFEDE--IHGRLKFNRRGLLGMANNGSRNSNTSQ 113 Query: 458 FFICTVPCNWLDGKHVVFGEVVEGMDVVKNIEKVGS 565 FFI L KH +FG++V + + N+ +G+ Sbjct: 114 FFITLDAAPELTNKHTMFGKIVG--NTIFNVLNIGN 147
>PPIL2_ASPFU (Q4WVU5) Peptidyl-prolyl cis-trans isomerase-like 2 (EC 5.2.1.8)| (PPIase) (Rotamase) (Cyclophilin-60) (Cyclophilin-like protein Cyp-60) Length = 579 Score = 70.9 bits (172), Expect = 3e-12 Identities = 49/125 (39%), Positives = 64/125 (51%), Gaps = 1/125 (0%) Frame = +2 Query: 155 GRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVIPDFMCQXXXXXXX 334 G + +EL+ + P+ V NF L +KG +YK +FHR I FM Q Sbjct: 322 GDVNLELHTEYAPKAVWNFIKLA--KKG--------YYKDVTFHRNIKGFMIQGGDPTGT 371 Query: 335 XXXXXESIYGEKFADE-KFVHKHTKPGILSMANAGPNTNGSQFFICTVPCNWLDGKHVVF 511 ESI+G+ F DE + KH G LSMAN G NTN SQFFI L+ KH +F Sbjct: 372 GRGG-ESIWGKYFNDEFEGPLKHDSRGTLSMANKGKNTNSSQFFIAYRALPHLNNKHTIF 430 Query: 512 GEVVE 526 G V++ Sbjct: 431 GHVID 435
>PPIL2_ASPOR (Q2U5W8) Peptidyl-prolyl cis-trans isomerase-like 2 (EC 5.2.1.8)| (PPIase) (Rotamase) (Cyclophilin-60) (Cyclophilin-like protein Cyp-60) Length = 570 Score = 70.5 bits (171), Expect = 4e-12 Identities = 50/126 (39%), Positives = 64/126 (50%), Gaps = 1/126 (0%) Frame = +2 Query: 152 AGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVIPDFMCQXXXXXX 331 +G I +EL + P+ V NF L +KG +YK +FHR I FM Q Sbjct: 308 SGDINLELQTEYAPKAVWNFIKLA--KKG--------YYKDVTFHRNIKGFMIQGGDPSG 357 Query: 332 XXXXXXESIYGEKFADE-KFVHKHTKPGILSMANAGPNTNGSQFFICTVPCNWLDGKHVV 508 ESI+G+ F DE + KH G LSMAN G NTN SQFFI L+ KH + Sbjct: 358 TGRGG-ESIWGKYFNDEFEGPLKHDSRGTLSMANKGKNTNSSQFFIAYRALPHLNNKHTI 416 Query: 509 FGEVVE 526 FG V++ Sbjct: 417 FGHVID 422
>PPIL2_EMENI (Q5AXT6) Peptidyl-prolyl cis-trans isomerase-like 2 (EC 5.2.1.8)| (PPIase) (Rotamase) (Cyclophilin-60) (Cyclophilin-like protein Cyp-60) Length = 580 Score = 70.1 bits (170), Expect = 5e-12 Identities = 50/126 (39%), Positives = 65/126 (51%), Gaps = 1/126 (0%) Frame = +2 Query: 152 AGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVIPDFMCQXXXXXX 331 +G I +EL+ + P+ V NF L +KG +YK +FHR I FM Q Sbjct: 319 SGDINLELHTEYAPKAVWNFIKLA--KKG--------YYKDVTFHRNIKGFMIQGGDPTG 368 Query: 332 XXXXXXESIYGEKFADE-KFVHKHTKPGILSMANAGPNTNGSQFFICTVPCNWLDGKHVV 508 ESI+G+ F DE + KH G LSMAN G NTN SQFFI L+ KH + Sbjct: 369 TGRGG-ESIWGKYFNDEFEGPLKHDSRGTLSMANKGKNTNSSQFFIAYRALPHLNLKHTI 427 Query: 509 FGEVVE 526 FG V++ Sbjct: 428 FGHVID 433
>PPIA_HELPY (O25982) Peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8) (PPIase)| (Rotamase) Length = 163 Score = 67.8 bits (164), Expect = 2e-11 Identities = 47/136 (34%), Positives = 64/136 (47%), Gaps = 2/136 (1%) Frame = +2 Query: 155 GRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVIPDFMCQXXXXXXX 334 G I +EL+ P+ V NF L K Y G +FHRVI F+ Q Sbjct: 28 GNIALELFYKDAPQAVSNFVTLA----------KEGFYNGLNFHRVIAGFVAQGGCPYGT 77 Query: 335 XXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFFICTVPCNWLDGKHVVFG 514 + A HK G +SMA+AG +T GSQFF+C V LDG+H VFG Sbjct: 78 GTGGPGHRIKCEVAHNPNKHKR---GSISMAHAGRDTGGSQFFLCFVDLPHLDGEHTVFG 134 Query: 515 EV--VEGMDVVKNIEK 556 ++ EG+ V+ I++ Sbjct: 135 KITSAEGLSVLDKIKQ 150
>PPIL3_EMENI (Q5BAH7) Peptidyl-prolyl cis-trans isomerase-like 3 (EC 5.2.1.8)| (PPIase) (Rotamase) Length = 211 Score = 67.0 bits (162), Expect = 4e-11 Identities = 55/179 (30%), Positives = 75/179 (41%), Gaps = 40/179 (22%) Frame = +2 Query: 155 GRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVIPDFMCQXXXXXXX 334 G + +EL+ +AVP+T ENF ALC Y + FHR+IP FM Q Sbjct: 10 GDLKVELFCEAVPKTAENFIALCAAGA----------YNDTPFHRLIPGFMIQGGDISLG 59 Query: 335 XXXXXE----------------SIYGEKFADEKFVH----KHTKPGILSMAN-------- 430 + SIY +++ +H +H GILSMA+ Sbjct: 60 PAANSQGTTPMLPFDDIPKGGTSIYHPSALNQE-IHLPALRHNTRGILSMASRPVKNQTA 118 Query: 431 ------AGPNTNGSQFFICTVPCNWLDGKHVVFGEVV------EGMDVVKNIEKVGSRS 571 GP NGSQFFI LDG VFG+V+ EG DV+ +EK ++ Sbjct: 119 PGSQGATGPTINGSQFFITFAAAPHLDGSSTVFGKVLNLTAEDEGGDVLSKLEKANVKT 177
>PPIA_HELPJ (Q9ZJH5) Peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8) (PPIase)| (Rotamase) Length = 162 Score = 66.6 bits (161), Expect = 5e-11 Identities = 46/136 (33%), Positives = 64/136 (47%), Gaps = 2/136 (1%) Frame = +2 Query: 155 GRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVIPDFMCQXXXXXXX 334 G I +EL+ P+ V NF L K Y G +FHRVI F+ Q Sbjct: 27 GNITLELFYKDAPQAVSNFVTLA----------KEGFYNGLNFHRVIAGFVAQGGCPYGT 76 Query: 335 XXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFFICTVPCNWLDGKHVVFG 514 E + A H+ G +SMA+AG +T GSQFF+C V LDG+H VFG Sbjct: 77 GTGGPEHRIKCEVAHNPNKHQR---GSISMAHAGRDTGGSQFFLCFVDLPHLDGEHTVFG 133 Query: 515 EV--VEGMDVVKNIEK 556 ++ E + V+ I++ Sbjct: 134 KITSAESLSVLDKIKQ 149
>PPI_SYNP7 (P29820) Peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8) (PPIase)| (Rotamase) Length = 145 Score = 64.7 bits (156), Expect = 2e-10 Identities = 49/134 (36%), Positives = 62/134 (46%), Gaps = 2/134 (1%) Frame = +2 Query: 155 GRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVIPDFMCQXXXXXXX 334 G I ++ + + P TV NF L + Y G +FHRVIP FM Q Sbjct: 11 GTIRLQFFDNDAPNTVANFVKL----------SQDGFYDGLTFHRVIPGFMSQGGCPHGT 60 Query: 335 XXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFFICTVPCNWLDGKHVVFG 514 G K E + H G LSMA+AG NT GSQFFIC P LDG H FG Sbjct: 61 GTGGP----GYKIPCEINDNPHLA-GTLSMAHAGRNTGGSQFFICHEPQPHLDGVHTTFG 115 Query: 515 EVV--EGMDVVKNI 550 + E + VV+++ Sbjct: 116 QTEDDESLKVVRSL 129
>CYP7_SCHPO (O42941) Peptidylprolyl isomerase cyp7 (EC 5.2.1.8) (Cyclophilin 7)| (Complexed with cdc5 protein 27) Length = 463 Score = 61.6 bits (148), Expect = 2e-09 Identities = 45/136 (33%), Positives = 63/136 (46%), Gaps = 1/136 (0%) Frame = +2 Query: 155 GRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVIPDFMCQXXXXXXX 334 G I +EL+ VP+ NF LC +Y G+ HRV+P+F+ Q Sbjct: 22 GDIQIELWCKEVPKACRNFIQLCLEG----------YYDGTIVHRVVPEFLIQGGDPTGT 71 Query: 335 XXXXXESIYGEKFADEKFVH-KHTKPGILSMANAGPNTNGSQFFICTVPCNWLDGKHVVF 511 ESIYGE FA E + + G++ MA N SQFFI P +GK +F Sbjct: 72 GMGG-ESIYGEPFAVETHPRLRFIRRGLVGMACTENEGNNSQFFITLGPTPEWNGKQTLF 130 Query: 512 GEVVEGMDVVKNIEKV 559 G VV D + N+ ++ Sbjct: 131 GRVVG--DTIYNVVRI 144
>PPIL3_ASPFU (Q4WMB6) Peptidyl-prolyl cis-trans isomerase-like 3 (EC 5.2.1.8)| (PPIase) (Rotamase) Length = 212 Score = 60.5 bits (145), Expect = 4e-09 Identities = 53/175 (30%), Positives = 71/175 (40%), Gaps = 41/175 (23%) Frame = +2 Query: 155 GRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVIPDFMCQXXXXXXX 334 G + +EL+ +AVP+T ENF ALC Y + FHR+ P FM Q Sbjct: 10 GDLKVELFCEAVPQTAENFLALCACGA----------YNNTPFHRIFPGFMIQGGDISLG 59 Query: 335 XXXXX-----------------ESIYGEKFADEKFVH----KHTKPGILSMAN------- 430 SIY + +++ +H +H GILSMA+ Sbjct: 60 PAPGTLNTLKPMLPVNEIPKGGTSIYHPRALNQE-IHLPALRHNARGILSMASRPVKDRT 118 Query: 431 -------AGPNTNGSQFFICTVPCNWLDGKHVVFGEVV------EGMDVVKNIEK 556 G NGSQFFI LDG VFG+V+ EG DV+ +EK Sbjct: 119 APGSQGATGATVNGSQFFITFAAAPHLDGASTVFGKVLNLSPQDEGGDVLSKLEK 173
>PPIL4_CRYNE (Q5KNY5) Peptidyl-prolyl cis-trans isomerase-like 4 (EC 5.2.1.8)| (PPIase) (Rotamase) Length = 504 Score = 60.1 bits (144), Expect = 5e-09 Identities = 47/148 (31%), Positives = 68/148 (45%), Gaps = 16/148 (10%) Frame = +2 Query: 155 GRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVIPDFMCQX---XXX 325 G ++++L D PRT ENF LC K +Y ++F V +F+ Q Sbjct: 10 GDLIIDLEVDKCPRTCENFIKLC----------KLKYYALNAFFNVSKNFIAQSGDPTAT 59 Query: 326 XXXXXXXXESIYGE--------KFADEKFVH--KHTKPGILSMANA--GPNTNGSQFFIC 469 +Y + ++ + ++ KHT G LSMA A P GSQFFI Sbjct: 60 GTGGESLASYVYSQSPSGPRPPRYFTPEILNSLKHTHKGTLSMAVAPINPPGCGSQFFIT 119 Query: 470 TVP-CNWLDGKHVVFGEVVEGMDVVKNI 550 ++LDGKH VFG V+EG+D + I Sbjct: 120 LADNIDYLDGKHAVFGHVIEGLDTLDKI 147
>PPIA_ACIAD (P42693) Peptidyl-prolyl cis-trans isomerase precursor (EC 5.2.1.8)| (PPIase) (Rotamase) Length = 188 Score = 57.8 bits (138), Expect = 2e-08 Identities = 45/141 (31%), Positives = 64/141 (45%), Gaps = 6/141 (4%) Frame = +2 Query: 155 GRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVIPDFMCQXXXXXXX 334 G I +ELY + P + +NF + K Y G+ FHRVIP+FM Q Sbjct: 31 GNIEIELYNNKAPISAKNFESYV----------KNNFYNGTIFHRVIPNFMIQGGGFETN 80 Query: 335 XXXXXESIYGEKFADEKFVHKHTKPGILSMAN-AGPNTNGSQFFICTVPCNWL-----DG 496 + + A + G L+MA + P++ SQFFI N+L D Sbjct: 81 MKEKATAAPIKNEASNGLANTR---GTLAMARTSNPDSATSQFFINVADNNFLNASRTDA 137 Query: 497 KHVVFGEVVEGMDVVKNIEKV 559 + VFG+V++GMDVV I V Sbjct: 138 GYAVFGKVIKGMDVVDKIANV 158
>PPIB_STRAT (P83221) Peptidyl-prolyl cis-trans isomerase cyp18 (EC 5.2.1.8)| (PPIase cyp18) (Rotamase cyp18) (SanCyp18) Length = 165 Score = 55.1 bits (131), Expect = 2e-07 Identities = 51/154 (33%), Positives = 64/154 (41%), Gaps = 13/154 (8%) Frame = +2 Query: 152 AGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVIPDFMCQXXXXXX 331 AGRIV+EL P+TVENF A +SG HY G+ FHRVI DFM Q Sbjct: 9 AGRIVLELNDAEAPKTVENFLAYV-------RSG---HYDGTIFHRVISDFMIQGGGFTP 58 Query: 332 XXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFFI-----------CTVP 478 + AD ++ + P++ +QFFI P Sbjct: 59 DMQQKSTLAPIQNEADNGL--RNDNYTVAMARTNDPHSATAQFFINVKDNAFLNHTSKTP 116 Query: 479 CNWLDGKHVVFGEVVEGMDVVKNIE--KVGSRSG 574 W + VFG V EG DVV I+ K GS G Sbjct: 117 NGW---GYAVFGRVTEGQDVVDAIKGVKTGSSRG 147
>CWC27_NEUCR (Q7SBX8) Peptidyl-prolyl isomerase cwc-27 (EC 5.2.1.8)| Length = 541 Score = 54.7 bits (130), Expect = 2e-07 Identities = 49/163 (30%), Positives = 64/163 (39%), Gaps = 27/163 (16%) Frame = +2 Query: 155 GRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVIPDFMCQXXXXXXX 334 G I +EL+ P T NF L +Y + FHR+IP F+ Q Sbjct: 22 GEIAVELFAKQTPLTCRNFLQLALDG----------YYDNTIFHRLIPGFIVQ-GGDPSG 70 Query: 335 XXXXXESIY-------------------------GEKFADEKFVH-KHTKPGILSMANAG 436 ESIY G F DE K + G+L MAN G Sbjct: 71 TGHGGESIYDNGALSGDLDPWPMDQRRGKNAGPHGVNFKDEFHSRLKFNRRGLLGMANEG 130 Query: 437 -PNTNGSQFFICTVPCNWLDGKHVVFGEVVEGMDVVKNIEKVG 562 P+TN SQFF + L GK+ +FG V D + N+ K+G Sbjct: 131 APDTNSSQFFFTLGKADELTGKNTMFGRVAG--DTIYNLAKIG 171
>CWC27_USTMA (Q4P7H2) Peptidyl-prolyl isomerase CWC27 (EC 5.2.1.8)| Length = 485 Score = 53.9 bits (128), Expect = 4e-07 Identities = 44/136 (32%), Positives = 56/136 (41%), Gaps = 1/136 (0%) Frame = +2 Query: 155 GRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVIPDFMCQXXXXXXX 334 G I + L+ P NF L Y FHR+IP+F+ Q Sbjct: 22 GTISIALFPTQAPLACRNFLTLALEG----------FYDNLVFHRLIPNFILQTGDPSAT 71 Query: 335 XXXXXESIYGEKFADEKFVH-KHTKPGILSMANAGPNTNGSQFFICTVPCNWLDGKHVVF 511 ESIYGE F E K + G+L MA TN SQFF+ L GKH + Sbjct: 72 GTGG-ESIYGEPFPIESHSRLKFNRRGLLGMAANQDRTNESQFFLTLDATPELTGKHTLM 130 Query: 512 GEVVEGMDVVKNIEKV 559 G+ VEG + +E V Sbjct: 131 GK-VEGKSIYTLVELV 145
>PPI_MIMIV (Q5UP71) Probable peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8)| (PPIase) (Rotamase) Length = 234 Score = 53.9 bits (128), Expect = 4e-07 Identities = 48/175 (27%), Positives = 74/175 (42%), Gaps = 25/175 (14%) Frame = +2 Query: 110 NPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGE------KGVGKSGKPLH-- 265 NP+V+ D+ + GR+ ++L++DA P VENF L G+ G GK H Sbjct: 14 NPRVYMDIVLNNEIIGRLQIKLFRDAFPAGVENFVQLTNGKTYRVNSNGTGKYKYNRHIN 73 Query: 266 --YKGSSFHRVIPDFMCQXXXXXXXXXXXXESIYGEK-----FADEKFVHKHTKPGILSM 424 Y+G FH V+ + ++Y ++ F D + + H G+LS+ Sbjct: 74 RTYEGCKFHNVLHNNYIVSGDIYNSNGSSAGTVYCDEPIPPVFGD--YFYPHESKGLLSL 131 Query: 425 A----NAGPNTNGSQFFIC---TVPCN---WLDGKHVVFGEVVEGMDVVKNIEKV 559 +G S F I P N LD VV G+V G+DV+ I + Sbjct: 132 VPYTDESGNRYYDSTFMITLDDIRPSNVLDELDRDQVVIGQVYGGLDVLDKINSM 186
>CP21C_ARATH (Q94A16) Peptidyl-prolyl cis-trans isomerase CYP21-3, mitochondrial| precursor (EC 5.2.1.8) (PPIase CYP21-3) (Rotamase CYP21-3) (Cyclophilin of 21 kDa 3) Length = 230 Score = 52.4 bits (124), Expect = 1e-06 Identities = 38/135 (28%), Positives = 55/135 (40%) Frame = +2 Query: 155 GRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVIPDFMCQXXXXXXX 334 G + +EL+KD P V+ F C ++KG F RV+ F+ Q Sbjct: 87 GSVTIELFKDTAPNVVDQFMKFCQDG----------YFKGFLFSRVVKHFVIQAGDSAEF 136 Query: 335 XXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFFICTVPCNWLDGKHVVFG 514 ++ K D H+ G N G +FFI + L+ K VFG Sbjct: 137 DAVKDWAL-DRKNIDTSLKHEEFMVGTPKAKN---EQGGFEFFIVSAQIKDLNEKLTVFG 192 Query: 515 EVVEGMDVVKNIEKV 559 V +G DVV+ IE+V Sbjct: 193 RVSKGQDVVQEIEEV 207
>PPIL4_NEUCR (Q871A4) Peptidyl-prolyl cis-trans isomerase-like 4 (EC 5.2.1.8)| (PPIase) (Rotamase) Length = 494 Score = 52.0 bits (123), Expect = 1e-06 Identities = 48/152 (31%), Positives = 66/152 (43%), Gaps = 19/152 (12%) Frame = +2 Query: 152 AGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVIPDFMCQXXXXX- 328 AG IV++L D P+ ENF LC K +Y S H + F Q Sbjct: 9 AGDIVIDLLVDYAPKMCENFLKLC----------KVKYYNFSPIHSIQKSFSFQTGDPLG 58 Query: 329 --XXXXXXXESIYGEKFADEK------FVH---KHTKPGILSMAN----AGPNTN--GSQ 457 +SI+G D H KH + G +SMA + P+T GSQ Sbjct: 59 PLSSESDGGQSIWGLLSGDPSEKTFPALFHPKLKHLERGTVSMATVPHPSDPDTRLAGSQ 118 Query: 458 FFICTVP-CNWLDGKHVVFGEVVEGMDVVKNI 550 F + ++LDGK +FG+VVEG DV++ I Sbjct: 119 FIVTLGDNTDYLDGKAAIFGKVVEGFDVLEKI 150
>PPIB_HAEIN (P44499) Peptidyl-prolyl cis-trans isomerase B (EC 5.2.1.8) (PPIase| B) (Rotamase B) Length = 169 Score = 51.6 bits (122), Expect = 2e-06 Identities = 46/150 (30%), Positives = 64/150 (42%), Gaps = 15/150 (10%) Frame = +2 Query: 155 GRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVIPDFMCQXXXXXXX 334 G I ++L D P T ENF C K Y + FHRVI FM Q Sbjct: 9 GDIKIKLDFDKAPVTAENFLNYC----------KDGFYNNTIFHRVIDGFMIQGGGMESG 58 Query: 335 XXXXXESIYGEKFADEKFVHKHTKPGILSMANAG-PNTNGSQFFICTVPCNWLDGK---- 499 + A+ + +K G ++MA P++ +QFFI ++L+ + Sbjct: 59 MREKATKAPIQNEANNRLSNKR---GTIAMARTSDPHSATAQFFINVADNDFLNYRSKEM 115 Query: 500 ----------HVVFGEVVEGMDVVKNIEKV 559 + VFGEVVEGMDVV I+KV Sbjct: 116 FGREVVQEWGYAVFGEVVEGMDVVDKIKKV 145
>PPIL4_GIBZE (Q4IE79) Peptidyl-prolyl cis-trans isomerase-like 4 (EC 5.2.1.8)| (PPIase) (Rotamase) Length = 605 Score = 51.6 bits (122), Expect = 2e-06 Identities = 48/154 (31%), Positives = 66/154 (42%), Gaps = 19/154 (12%) Frame = +2 Query: 152 AGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVIPDFMCQXXXXXX 331 AG IV++L D P+ ENF LC K +Y S H V +F Q Sbjct: 9 AGDIVIDLLVDHAPKLCENFLKLC----------KVKYYNFSPVHSVQKNFSFQTGDPLG 58 Query: 332 XXXXXXE---SIYGEKFADEK------FVH---KHTKPGILSMANAGPNTN------GSQ 457 + SI+G D F H KH + G +SMA A ++ GSQ Sbjct: 59 PLSKDSDGGSSIWGHLSGDPSERTFPAFFHPKLKHLERGTVSMATAPLQSDPDVRVAGSQ 118 Query: 458 FFICT-VPCNWLDGKHVVFGEVVEGMDVVKNIEK 556 F I ++LDGK +FG+VVEG + + I + Sbjct: 119 FIITLGQDTDFLDGKAAIFGKVVEGFEALDKINE 152
>PPIB_ECOLI (P23869) Peptidyl-prolyl cis-trans isomerase B (EC 5.2.1.8) (PPIase| B) (Rotamase B) Length = 164 Score = 50.1 bits (118), Expect = 5e-06 Identities = 47/151 (31%), Positives = 66/151 (43%), Gaps = 10/151 (6%) Frame = +2 Query: 155 GRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVIPDFMCQXXXXXXX 334 G IV++ + D P TV+NF C + Y + FHRVI FM Q Sbjct: 9 GDIVIKTFDDKAPETVKNFLDYC----------REGFYNNTIFHRVINGFMIQGGGFEPG 58 Query: 335 XXXXXESIYGEKFADEKFVHKHTKPGILSMANA-GPNTNGSQFFICTVPCNWLDGK---- 499 E +E G L+MA P++ +QFFI V ++L+ Sbjct: 59 MKQKATK---EPIKNEANNGLKNTRGTLAMARTQAPHSATAQFFINVVDNDFLNFSGESL 115 Query: 500 ----HVVFGEVVEGMDVVKNIEKVGS-RSGI 577 + VF EVV+GMDVV I+ V + RSG+ Sbjct: 116 QGWGYCVFAEVVDGMDVVDKIKGVATGRSGM 146
>PPIA_ECOLI (P0AFL3) Peptidyl-prolyl cis-trans isomerase A precursor (EC| 5.2.1.8) (PPIase A) (Rotamase A) (Cyclophilin A) Length = 190 Score = 49.7 bits (117), Expect = 7e-06 Identities = 50/159 (31%), Positives = 68/159 (42%), Gaps = 10/159 (6%) Frame = +2 Query: 152 AGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVIPDFMCQXXXXXX 331 AG I +EL K P +V+NF SG Y ++FHRVIP FM Q Sbjct: 37 AGNIELELDKQKAPVSVQNFVDYVN-------SG---FYNNTTFHRVIPGFMIQGGGFTE 86 Query: 332 XXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFFICTVPCNWLDGK---- 499 + + AD ++T+ I A ++ SQFFI +LD Sbjct: 87 QMQQKKPNPPIKNEADNGL--RNTRGTIAMARTADKDSATSQFFINVADNAFLDHGQRDF 144 Query: 500 -HVVFGEVVEGMDVVKNIEK-----VGSRSGICFKQVVI 598 + VFG+VV+GMDV I + VG + K VVI Sbjct: 145 GYAVFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVI 183
>PPIA_ECOL6 (P0AFL4) Peptidyl-prolyl cis-trans isomerase A precursor (EC| 5.2.1.8) (PPIase A) (Rotamase A) (Cyclophilin A) Length = 190 Score = 49.7 bits (117), Expect = 7e-06 Identities = 50/159 (31%), Positives = 68/159 (42%), Gaps = 10/159 (6%) Frame = +2 Query: 152 AGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVIPDFMCQXXXXXX 331 AG I +EL K P +V+NF SG Y ++FHRVIP FM Q Sbjct: 37 AGNIELELDKQKAPVSVQNFVDYVN-------SG---FYNNTTFHRVIPGFMIQGGGFTE 86 Query: 332 XXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFFICTVPCNWLDGK---- 499 + + AD ++T+ I A ++ SQFFI +LD Sbjct: 87 QMQQKKPNPPIKNEADNGL--RNTRGTIAMARTADKDSATSQFFINVADNAFLDHGQRDF 144 Query: 500 -HVVFGEVVEGMDVVKNIEK-----VGSRSGICFKQVVI 598 + VFG+VV+GMDV I + VG + K VVI Sbjct: 145 GYAVFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVI 183
>PPIA_ECO57 (P0AFL5) Peptidyl-prolyl cis-trans isomerase A precursor (EC| 5.2.1.8) (PPIase A) (Rotamase A) (Cyclophilin A) Length = 190 Score = 49.7 bits (117), Expect = 7e-06 Identities = 50/159 (31%), Positives = 68/159 (42%), Gaps = 10/159 (6%) Frame = +2 Query: 152 AGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVIPDFMCQXXXXXX 331 AG I +EL K P +V+NF SG Y ++FHRVIP FM Q Sbjct: 37 AGNIELELDKQKAPVSVQNFVDYVN-------SG---FYNNTTFHRVIPGFMIQGGGFTE 86 Query: 332 XXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFFICTVPCNWLDGK---- 499 + + AD ++T+ I A ++ SQFFI +LD Sbjct: 87 QMQQKKPNPPIKNEADNGL--RNTRGTIAMARTADKDSATSQFFINVADNAFLDHGQRDF 144 Query: 500 -HVVFGEVVEGMDVVKNIEK-----VGSRSGICFKQVVI 598 + VFG+VV+GMDV I + VG + K VVI Sbjct: 145 GYAVFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVI 183
>PPIA_PSEAE (Q59641) Peptidyl-prolyl cis-trans isomerase A precursor (EC| 5.2.1.8) (PPIase A) (Rotamase A) (Cyclophilin A) Length = 187 Score = 49.3 bits (116), Expect = 9e-06 Identities = 51/163 (31%), Positives = 71/163 (43%), Gaps = 6/163 (3%) Frame = +2 Query: 89 IPASEMANPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHY 268 + A+ A P V ++G I +EL P +V+NF SG +Y Sbjct: 19 LAATPAAKPHVLIATSLG-----EIEVELDPAKAPISVKNFLEYVD-------SG---YY 63 Query: 269 KGSSFHRVIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGILSMANAG-PNT 445 G+ FHRVIP FM Q + AD +++ G L+MA G ++ Sbjct: 64 DGTLFHRVIPGFMVQTGGFSAGMQEKKTRAPIKNEADNGLLNER---GTLAMARTGVVDS 120 Query: 446 NGSQFFICTVPCNWL-----DGKHVVFGEVVEGMDVVKNIEKV 559 SQFFI ++L D + VFG+VV GM VV I KV Sbjct: 121 ATSQFFINLTDNDFLNHGARDFGYAVFGKVVRGMGVVDQIAKV 163
>PPIL4_ASPFU (Q4WAQ9) Peptidyl-prolyl cis-trans isomerase-like 4 (EC 5.2.1.8)| (PPIase) (Rotamase) Length = 459 Score = 47.8 bits (112), Expect = 3e-05 Identities = 46/150 (30%), Positives = 64/150 (42%), Gaps = 18/150 (12%) Frame = +2 Query: 155 GRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVIPDFMCQXXXXXXX 334 G IV++L D P+ ENF LC K +Y S H V +F Q Sbjct: 10 GDIVIDLLVDESPKACENFLKLC----------KVKYYNFSPVHSVQKNFTFQTGDPLGP 59 Query: 335 XXXXXE---SIYGEKFADEKFVH--------KHTKPGILSMANAGPNTN-----GSQFFI 466 + SI+G K KHT+ G +SMA + + + FI Sbjct: 60 DSPESDGGSSIWGLLEGPVKRTFSLKLSPKLKHTERGTVSMATVPSSHDPDERLAASQFI 119 Query: 467 CTVPCN--WLDGKHVVFGEVVEGMDVVKNI 550 T+ N +LDGK +FG+VVEG DV++ I Sbjct: 120 VTLEDNLDYLDGKAAIFGKVVEGFDVLEKI 149
>PPIA_SALTY (P20753) Peptidyl-prolyl cis-trans isomerase A precursor (EC| 5.2.1.8) (PPIase A) (Rotamase A) Length = 190 Score = 47.4 bits (111), Expect = 3e-05 Identities = 49/159 (30%), Positives = 67/159 (42%), Gaps = 10/159 (6%) Frame = +2 Query: 152 AGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVIPDFMCQXXXXXX 331 AG I +EL P +V+NF SG Y ++FHRVIP FM Q Sbjct: 37 AGNIELELNSQKAPVSVKNFVDYVN-------SG---FYNNTTFHRVIPGFMIQGGGFNE 86 Query: 332 XXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFFICTVPCNWLDGK---- 499 + + AD ++T+ I A ++ SQFFI +LD Sbjct: 87 QMQQKKPNPPIKNEADNGL--RNTRGTIAMARTADKDSATSQFFINVADNAFLDHGQRDF 144 Query: 500 -HVVFGEVVEGMDVVKNIEK-----VGSRSGICFKQVVI 598 + VFG+VV+GMDV I + VG + K VVI Sbjct: 145 GYAVFGKVVKGMDVADKISQVPTHDVGPYQNVPTKPVVI 183
>PPIL4_ASPOR (Q2U256) Peptidyl-prolyl cis-trans isomerase-like 4 (EC 5.2.1.8)| (PPIase) (Rotamase) Length = 461 Score = 47.4 bits (111), Expect = 3e-05 Identities = 46/152 (30%), Positives = 64/152 (42%), Gaps = 18/152 (11%) Frame = +2 Query: 155 GRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVIPDFMCQXXXXXXX 334 G IV++L D P+ ENF LC K +Y S H V +F Q Sbjct: 10 GDIVIDLLVDECPKACENFLKLC----------KVKYYNFSPVHSVQKNFTFQTGDPLGP 59 Query: 335 XXXXXE---SIYGEKFADEKFVH--------KHTKPGILSMANAGPNTNGSQF-----FI 466 + SI+G K KH + G +SMA + Q FI Sbjct: 60 DSSESDGGSSIWGLLEGPPKRTFSLEPPPKLKHDERGTVSMATVPSPHDPDQRIAASQFI 119 Query: 467 CTVPCN--WLDGKHVVFGEVVEGMDVVKNIEK 556 T+ N +LDGK V+FG+VVEG DV++ + + Sbjct: 120 VTLGENLDYLDGKAVIFGKVVEGFDVLEKVNE 151
>CWC27_GIBZE (Q4IPB3) Peptidyl-prolyl isomerase CWC27 (EC 5.2.1.8)| Length = 548 Score = 47.4 bits (111), Expect = 3e-05 Identities = 45/163 (27%), Positives = 62/163 (38%), Gaps = 27/163 (16%) Frame = +2 Query: 155 GRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVIPDFMCQXXXXXXX 334 G + +EL+ P T NF L +Y + FHR++P F+ Q Sbjct: 22 GELSVELFAKQAPLTCRNFLQLALDG----------YYDNTIFHRLVPGFILQGGDPTGT 71 Query: 335 XXXXXESIY-------------------------GEKFADEKFVH-KHTKPGILSMANAG 436 ESIY G F DE K + G+L AN Sbjct: 72 GNGG-ESIYDGGAFSGDLDPWPMDQRMGKNAGPTGINFKDEFHSRLKFNRRGLLGSANES 130 Query: 437 -PNTNGSQFFICTVPCNWLDGKHVVFGEVVEGMDVVKNIEKVG 562 P+TN SQFF L+GK+ +FG + D V N+ K+G Sbjct: 131 RPDTNSSQFFFTLDTAEELNGKNTMFGRIAG--DTVYNLAKMG 171
>PPIL4_EMENI (Q5ARI5) Peptidyl-prolyl cis-trans isomerase-like 4 (EC 5.2.1.8)| (PPIase) (Rotamase) Length = 461 Score = 46.6 bits (109), Expect = 6e-05 Identities = 47/153 (30%), Positives = 66/153 (43%), Gaps = 19/153 (12%) Frame = +2 Query: 155 GRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVIPDFMCQXXXXX-- 328 G IV++L D P+ ENF LC K +Y S F+ V +F Q Sbjct: 10 GDIVIDLLVDESPKACENFLKLC----------KVKYYNFSPFYSVQKNFSFQTGDPIGP 59 Query: 329 -XXXXXXXESIYGEKFADEKFVH--------KHTKPGILSMANAGPNTNGSQF------F 463 SI+G K KH + G +SMA A P+ + F Sbjct: 60 DSPDSNGGSSIWGLLEGPSKQAVPLALPPKLKHDEKGTVSMA-AVPSPHDPDLRLVTSQF 118 Query: 464 ICTVPCN--WLDGKHVVFGEVVEGMDVVKNIEK 556 I T+ N +LDGK V+FG+VVEG DV++ + + Sbjct: 119 IVTLGDNLDYLDGKAVIFGKVVEGFDVLEKVNE 151
>CWC27_ASPFU (Q4WE62) Peptidyl-prolyl isomerase cwc27 (EC 5.2.1.8)| Length = 559 Score = 44.7 bits (104), Expect = 2e-04 Identities = 43/153 (28%), Positives = 64/153 (41%), Gaps = 18/153 (11%) Frame = +2 Query: 155 GRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVIPDFMCQXXXXXXX 334 G I + L+ + P T +NF C +Y G+ FHR++PDF+ Q Sbjct: 22 GPIHIALFANQTPLTCKNFLQHCLDN----------YYAGTIFHRIVPDFIVQGGDPTGT 71 Query: 335 XXXXXESIY--------------GEKFADEKFVH---KHTKPGILSMANAGPNTNGSQFF 463 SIY EK +H + + G++ MA + T GSQFF Sbjct: 72 GSGGT-SIYEYPEFEYDPEARDPNEKVVLRDELHSRLRFNRRGLVGMAKSEDGTYGSQFF 130 Query: 464 ICTVPC-NWLDGKHVVFGEVVEGMDVVKNIEKV 559 I L+G+ +FG VEG D + N+ K+ Sbjct: 131 ITLANAERELNGQCTLFGR-VEG-DSIYNVLKI 161
>PPIB_MYCTU (Q50639) Probable peptidyl-prolyl cis-trans isomerase B (EC| 5.2.1.8) (PPIase B) (Rotamase B) Length = 308 Score = 44.3 bits (103), Expect = 3e-04 Identities = 50/189 (26%), Positives = 79/189 (41%), Gaps = 14/189 (7%) Frame = +2 Query: 50 PIPPKTLAPIPIPIPASEMANP-KVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCT 226 P P K + P+ +P +P +V M G I + L + P TV +F +L Sbjct: 117 PSPDKAVKPVKLPRTGKVPTDPAQVSVSMVTN---QGNIGLMLANNESPCTVNSFVSLA- 172 Query: 227 GEKGVGKSGKPLHYKGSSFHRVIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTK 406 ++G +KG++ HR+ M G +FA+E +++ Sbjct: 173 -QQGF--------FKGTTCHRLTTSPMLAVLQCGDPKGDGTGGP-GYQFANEYPTDQYSA 222 Query: 407 P------------GILSMANAGPNTNGSQFFICTVPCNWLDGKHVVFGEV-VEGMDVVKN 547 G L+MANAGPNTN SQFF+ + L ++ VFG + +G+ + Sbjct: 223 NDPKLNEPVIYPRGTLAMANAGPNTNSSQFFM-VYRDSKLPPQYTVFGTIQADGLTTLDK 281 Query: 548 IEKVGSRSG 574 I K G G Sbjct: 282 IAKAGVAGG 290
>PPIL4_SCHPO (Q9UUE4) Peptidyl-prolyl cis-trans isomerase cyp6 (EC 5.2.1.8)| (PPIase cyp6) (Rotamase cyp8) Length = 432 Score = 44.3 bits (103), Expect = 3e-04 Identities = 39/148 (26%), Positives = 65/148 (43%), Gaps = 16/148 (10%) Frame = +2 Query: 155 GRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVIPDFMCQXXXXXXX 334 G +V++L+ P+T ENF LC K +Y F+ + ++ CQ Sbjct: 10 GDLVIDLFVKEAPKTCENFLKLC----------KLKYYNFCPFYNIQHNYTCQTGDPLGP 59 Query: 335 XXXXXESIY-----GEKFADEKFVHK--HTKPGILSMANAGPNTN-------GSQFFICT 472 ++ G +F +F H K G++SM+ A ++ GSQF I T Sbjct: 60 TGDGGRCVWNVLNKGTRFFKAEFNPSLVHNKMGLVSMSTATISSRDDKLLVCGSQFII-T 118 Query: 473 VPCN--WLDGKHVVFGEVVEGMDVVKNI 550 + N LD ++ ++G+V EG D + I Sbjct: 119 LSDNLEGLDERYPIYGQVAEGFDTLLKI 146
>PPIL4_USTMA (P0C196) Peptidyl-prolyl cis-trans isomerase-like 4 (EC 5.2.1.8)| (PPIase) (Rotamase) Length = 551 Score = 44.3 bits (103), Expect = 3e-04 Identities = 43/164 (26%), Positives = 64/164 (39%), Gaps = 29/164 (17%) Frame = +2 Query: 155 GRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVIPDFMCQXXXXXXX 334 G IV++L+ + PR+ NF LC+ +YK ++F RV DF+ Q Sbjct: 10 GDIVIDLHTELAPRSCTNFLKLCSKH----------YYKLNAFFRVEKDFLAQTGDPSNT 59 Query: 335 X-----------XXXXESIYGEKFADEKFVH--KHTKPGILSMANAGPNTNG-------- 451 +S F E KH K G +S A + G Sbjct: 60 GKGGASIWSQLPSTSQDSSTSTYFTPESSDGQLKHLKKGTVSFACFRKHVQGADEDGEGG 119 Query: 452 -------SQFFICTVP-CNWLDGKHVVFGEVVEGMDVVKNIEKV 559 SQFF+ ++LDG+H FG VVEG + ++K+ Sbjct: 120 SCELLAGSQFFVTLKDELDYLDGRHAPFGMVVEGHEPGGTLDKI 163
>PPIB_MYCLE (P46697) Probable peptidyl-prolyl cis-trans isomerase B (EC| 5.2.1.8) (PPIase B) (Rotamase B) Length = 295 Score = 43.9 bits (102), Expect = 4e-04 Identities = 25/56 (44%), Positives = 35/56 (62%), Gaps = 1/56 (1%) Frame = +2 Query: 410 GILSMANAGPNTNGSQFFICTVPCNWLDGKHVVFGEV-VEGMDVVKNIEKVGSRSG 574 G L+MAN+GPNTNGSQFF+ + L ++ VFG + +G+ + I K G SG Sbjct: 223 GTLAMANSGPNTNGSQFFL-VYHDSQLPPEYTVFGTIQADGLATLDKIAKGGIASG 277
>PPIA_DICD3 (O53021) Peptidyl-prolyl cis-trans isomerase A precursor (EC| 5.2.1.8) (PPIase A) (Rotamase A) (Cyclophilin A) Length = 190 Score = 43.9 bits (102), Expect = 4e-04 Identities = 49/160 (30%), Positives = 63/160 (39%), Gaps = 11/160 (6%) Frame = +2 Query: 152 AGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVIPDFMCQXXXXXX 331 AG I + L P V+NF SG Y G+ FHRVIP FM Q Sbjct: 36 AGNIELALDDQKAPVFVKNFVDYVN-------SG---FYNGTIFHRVIPGFMVQGGGFSS 85 Query: 332 XXXXXXESIYGEKFADEKFVHKHTKPGILSMANAGPNTNG-SQFFICTVPCNWLDG---- 496 + + AD G +SMA + SQFFI +LD Sbjct: 86 DMKQKATNPPVKNEADNGL---RNLRGTISMARTSEKDSATSQFFINVADNAFLDHGQRD 142 Query: 497 -KHVVFGEVVEGMDVVKNI-----EKVGSRSGICFKQVVI 598 + VFG+VV+GM+V I E VG + K +VI Sbjct: 143 FGYAVFGKVVKGMEVADKISQVQTENVGPYQNVPSKPIVI 182
>TLP20_SPIOL (P82536) Peptidyl-prolyl cis-trans isomerase TLP20, chloroplast (EC| 5.2.1.8) (PPIase) (Rotamase) (Thylakoid lumen PPIase of 20 kDa) (Thylakoid lumenal 18 kDa protein) (P18) (Fragments) Length = 45 Score = 41.2 bits (95), Expect = 0.002 Identities = 18/41 (43%), Positives = 27/41 (65%) Frame = +2 Query: 92 PASEMANPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFR 214 P KV+FD+++G P G++V+ L+ D VP+T ENFR Sbjct: 6 PLQSKVTNKVYFDISIGN-PVGKVVIGLFGDDVPQTAENFR 45
>CYPH_BETVE (P81531) Peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8) (PPIase)| (Rotamase) (Cyclophilin) (Cyclosporin A-binding protein) (Pollen allergen Bet v 7) (Fragments) Length = 42 Score = 40.4 bits (93), Expect = 0.004 Identities = 22/34 (64%), Positives = 22/34 (64%) Frame = +2 Query: 350 ESIYGEKFADEKFVHKHTKPGILSMANAGPNTNG 451 ESIYG K D T PGILSMANAGP TNG Sbjct: 11 ESIYGAK--DXXXXXXXTGPGILSMANAGPGTNG 42
>CYP8_YEAST (P53728) Peptidyl-prolyl cis-trans isomerase CYP8 (EC 5.2.1.8)| (PPIase) (Rotamase) Length = 308 Score = 40.4 bits (93), Expect = 0.004 Identities = 43/169 (25%), Positives = 70/169 (41%), Gaps = 5/169 (2%) Frame = +2 Query: 62 KTLAPIPIPIPASEMANPKVFFDMTVGGAPAGRIV-MELYKDAVPRTVENFRALCTGEKG 238 K AP P P + N + F AGR++ ++LY VP+TV F K Sbjct: 38 KKYAPDP---PITHNVNIGIVFTDPESSEEAGRLITIDLYGTMVPKTVMTFCQYVDSVKD 94 Query: 239 VGKSGKPLHYKGSSFHRVIPDFMCQXXXXXXXXXXXXESIYGEKFADEKFVHKHTKPGIL 418 + + + F +++P+ + E + K +E H +PG + Sbjct: 95 -RLASRHSYSPERDFDKILPNGAIEGSSVSSSSIEETEML-APKLPEENHSLIHDRPGRV 152 Query: 419 SMANAGPNTNGSQFFICTVPCNWLDGKHVVFGEVVEG----MDVVKNIE 553 SM + G +F I T L+G+ VVFG+V G MD + N++ Sbjct: 153 SMIK---DDKGLKFIIETSETP-LEGESVVFGQVTAGLKDLMDKLANVK 197
>PPI1_SYNY3 (P72704) Probable peptidyl-prolyl cis-trans isomerase sll0227| precursor (EC 5.2.1.8) (PPIase) (Rotamase) Length = 246 Score = 39.7 bits (91), Expect = 0.007 Identities = 47/179 (26%), Positives = 70/179 (39%), Gaps = 30/179 (16%) Frame = +2 Query: 110 NPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHR 289 N K +M V G P I++E+ + P T NF L E+G Y G +FHR Sbjct: 63 NGKATVEMMVNGQP---IIIEVDGENAPITAGNFVDLV--EQGF--------YNGLTFHR 109 Query: 290 VIPDFMCQXXXXXXXXXXXXES--------------------------IYGEKFADEKF- 388 V+ F+ Q +Y ++ Sbjct: 110 VVDGFVAQGGDPKGDGTGGYVDKNTQRPRNIPLEIKVDPAVENAPETPVYSRALGNQAGF 169 Query: 389 -VHKHTKPGILSMANAG-PNTNGSQF-FICTVPCNWLDGKHVVFGEVVEGMDVVKNIEK 556 V K G ++MA + P++ SQF F + +LDG + VFG V +GMDVV I++ Sbjct: 170 PVMLPHKTGAVAMARSQMPDSASSQFYFTLSDETGFLDGDYAVFGYVTQGMDVVLKIKQ 228
>CWC27_EMENI (Q5AUG9) Peptidyl-prolyl isomerase cwc27 (EC 5.2.1.8)| Length = 558 Score = 39.7 bits (91), Expect = 0.007 Identities = 42/159 (26%), Positives = 63/159 (39%), Gaps = 18/159 (11%) Frame = +2 Query: 155 GRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVIPDFMCQXXXXXXX 334 G + + L+ P T NF C +Y G+ FHRV+PDF+ Q Sbjct: 22 GPLHIALFAKQTPLTCRNFLQHCMDN----------YYAGTIFHRVVPDFIIQGGDPTGT 71 Query: 335 XXXXXESIY--------------GEKFADEKFVH---KHTKPGILSMANAGPNTNGSQFF 463 SIY EK +H + + G++ MA + + GSQFF Sbjct: 72 GSGGT-SIYEYPEFEYDPDARDPNEKVVLRDEIHSRLRFNRRGLVGMAKSEDGSYGSQFF 130 Query: 464 ICTVPC-NWLDGKHVVFGEVVEGMDVVKNIEKVGSRSGI 577 I L+G+ +FG +EG D + N+ K+ I Sbjct: 131 ITLANTERELNGQCTLFGR-LEG-DSLYNMLKIAEAERI 167
>IRX3_HUMAN (P78415) Iroquois-class homeodomain protein IRX-3 (Iroquois| homeobox protein 3) (Homeodomain protein IRXB1) Length = 501 Score = 36.6 bits (83), Expect = 0.058 Identities = 16/42 (38%), Positives = 24/42 (57%), Gaps = 1/42 (2%) Frame = +2 Query: 2 SQSPKPEEIPIRAPEFPIPPKTLAP-IPIPIPASEMANPKVF 124 S +P P + + +P P PP +L P P P PAS + PK++ Sbjct: 309 SLAPAPPPVAVASPSLPSPPVSLDPCAPAPAPASALQKPKIW 350
>PPIA_NAEFO (P84342) Peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8) (PPIase)| (Rotamase) (Cyclophilin) (NF008) (Fragment) Length = 21 Score = 34.7 bits (78), Expect = 0.22 Identities = 15/21 (71%), Positives = 17/21 (80%) Frame = +2 Query: 380 EKFVHKHTKPGILSMANAGPN 442 E F KHT+PG+LSMANAG N Sbjct: 1 ENFKIKHTEPGLLSMANAGKN 21
>EPS8_MOUSE (Q08509) Epidermal growth factor receptor kinase substrate 8| Length = 821 Score = 33.1 bits (74), Expect = 0.64 Identities = 16/35 (45%), Positives = 22/35 (62%), Gaps = 3/35 (8%) Frame = +2 Query: 41 PEFPIPPKTLAPIPIPIPAS---EMANPKVFFDMT 136 P P PP T AP+P+P+P S ++ PKV D+T Sbjct: 620 PSAPSPPPTPAPVPVPLPPSVPAPVSVPKVPADVT 654
>NR2E1_XENLA (P70052) Orphan nuclear receptor NR2E1 (Nuclear receptor TLX)| (Tailless homolog) (Tll) (xTLL) Length = 386 Score = 32.7 bits (73), Expect = 0.84 Identities = 15/51 (29%), Positives = 26/51 (50%), Gaps = 4/51 (7%) Frame = +2 Query: 47 FPIPPKTLAPIPIPIPASEMANP----KVFFDMTVGGAPAGRIVMELYKDA 187 +P P + + +PA NP +VFF T+G P R++ ++YK + Sbjct: 334 YPTQPCRFGKLLLLLPALRSINPSTIEEVFFKKTIGNVPITRVLSDMYKSS 384
>GPA1_TRIVA (Q86D96) Guanine nucleotide-binding protein alpha-1 subunit (G| alpha-1) (GTP-binding protein alpha subunit 1) Length = 402 Score = 32.3 bits (72), Expect = 1.1 Identities = 17/36 (47%), Positives = 18/36 (50%), Gaps = 1/36 (2%) Frame = +2 Query: 11 PKPEEIPIRAPE-FPIPPKTLAPIPIPIPASEMANP 115 PKPE P P+ P PPK P P P PA E P Sbjct: 31 PKPEPQPQPEPQPQPEPPKPAEPAPAPAPAPEPQKP 66
>EPS8_PONPY (Q5R4H4) Epidermal growth factor receptor kinase substrate 8| Length = 822 Score = 32.3 bits (72), Expect = 1.1 Identities = 13/27 (48%), Positives = 16/27 (59%) Frame = +2 Query: 29 PIRAPEFPIPPKTLAPIPIPIPASEMA 109 P P P PP T AP+P+P+P S A Sbjct: 617 PADTPPAPSPPPTPAPVPVPLPPSTPA 643
>EPS8_HUMAN (Q12929) Epidermal growth factor receptor kinase substrate 8| Length = 822 Score = 32.3 bits (72), Expect = 1.1 Identities = 13/27 (48%), Positives = 16/27 (59%) Frame = +2 Query: 29 PIRAPEFPIPPKTLAPIPIPIPASEMA 109 P P P PP T AP+P+P+P S A Sbjct: 617 PADTPPAPSPPPTPAPVPVPLPPSTPA 643
>PTPRN_RAT (Q63259) Receptor-type tyrosine-protein phosphatase-like N| precursor (R-PTP-N) (105 kDa islet cell antigen) (ICA105) (PTP IA-2) (PTPLP) (Brain-enriched membrane-associated protein tyrosine phosphatase) (BEM-3) Length = 983 Score = 32.3 bits (72), Expect = 1.1 Identities = 26/84 (30%), Positives = 37/84 (44%) Frame = +2 Query: 32 IRAPEFPIPPKTLAPIPIPIPASEMANPKVFFDMTVGGAPAGRIVMELYKDAVPRTVENF 211 + +P FP PPKT +P+ I E +P TV G P+ R E Y V T + Sbjct: 427 VLSPGFPEPPKTSSPLGISAVLLEKKSPLGQSQPTVVGQPSARPSAEEYGYIV--TDQKP 484 Query: 212 RALCTGEKGVGKSGKPLHYKGSSF 283 +L G K + + +H SF Sbjct: 485 LSLVAGVKLLEILAEHVHMTSGSF 508
>TEGU_EBV (P03186) Large tegument protein| Length = 3149 Score = 32.0 bits (71), Expect = 1.4 Identities = 14/40 (35%), Positives = 21/40 (52%) Frame = +2 Query: 2 SQSPKPEEIPIRAPEFPIPPKTLAPIPIPIPASEMANPKV 121 S +P P + AP P+ IPIP+P + +NPK+ Sbjct: 477 SPTPHPAPVSTIAPSVTPSPRLPLQIPIPLPQAAPSNPKI 516
>FTSK_STRCO (O86810) DNA translocase ftsK| Length = 917 Score = 31.2 bits (69), Expect = 2.4 Identities = 17/47 (36%), Positives = 25/47 (53%), Gaps = 2/47 (4%) Frame = +2 Query: 62 KTLAPIPIPIPASEMANPKVFFDMT--VGGAPAGRIVMELYKDAVPR 196 ++ P P P+PA+ K+ D T GG PAG V +L K +P+ Sbjct: 365 ESTTPTPTPVPAARPQPGKLKKDATKAAGGEPAGGAVPDLTKTPLPK 411
>DME_ARATH (Q8LK56) Transcriptional activator DEMETER (DNA glycosylase-related| protein DME) Length = 1729 Score = 30.4 bits (67), Expect = 4.2 Identities = 15/50 (30%), Positives = 24/50 (48%) Frame = +2 Query: 11 PKPEEIPIRAPEFPIPPKTLAPIPIPIPASEMANPKVFFDMTVGGAPAGR 160 P PEE + + P+PP++ P+ IP+ + P GAP+ R Sbjct: 1402 PAPEERSLTSATIPVPPESFPPVAIPM----IELPLPLEKSLASGAPSNR 1447
>SYP2L_HUMAN (Q9H987) Synaptopodin 2-like protein| Length = 977 Score = 30.4 bits (67), Expect = 4.2 Identities = 13/38 (34%), Positives = 22/38 (57%), Gaps = 1/38 (2%) Frame = +2 Query: 5 QSPKPEEIPIRAPEFPIPPKTL-APIPIPIPASEMANP 115 QSP P E+ + +P P+ P+ AP+P P+ + +P Sbjct: 94 QSPSPHELQVLSPLSPLSPEPPGAPVPQPLQPGSLRSP 131
>NR2E1_MOUSE (Q64104) Orphan nuclear receptor NR2E1 (Nuclear receptor TLX)| (Tailless homolog) (Tll) (mTll) Length = 385 Score = 30.4 bits (67), Expect = 4.2 Identities = 14/51 (27%), Positives = 26/51 (50%), Gaps = 4/51 (7%) Frame = +2 Query: 47 FPIPPKTLAPIPIPIPASEMANP----KVFFDMTVGGAPAGRIVMELYKDA 187 +P P + + +PA +P +VFF T+G P R++ ++YK + Sbjct: 333 YPTQPCRFGKLLLLLPALRSISPSTIEEVFFKKTIGNVPITRLLSDMYKSS 383
>NR2E1_HUMAN (Q9Y466) Orphan nuclear receptor NR2E1 (Nuclear receptor TLX)| (Tailless homolog) (Tll) (hTll) Length = 385 Score = 30.4 bits (67), Expect = 4.2 Identities = 14/51 (27%), Positives = 26/51 (50%), Gaps = 4/51 (7%) Frame = +2 Query: 47 FPIPPKTLAPIPIPIPASEMANP----KVFFDMTVGGAPAGRIVMELYKDA 187 +P P + + +PA +P +VFF T+G P R++ ++YK + Sbjct: 333 YPTQPCRFGKLLLLLPALRSISPSTIEEVFFKKTIGNVPITRLLSDMYKSS 383
>NR2E1_CHICK (Q91379) Orphan nuclear receptor NR2E1 (Nuclear receptor TLX)| (Tailless homolog) (Tll) Length = 385 Score = 30.4 bits (67), Expect = 4.2 Identities = 14/51 (27%), Positives = 26/51 (50%), Gaps = 4/51 (7%) Frame = +2 Query: 47 FPIPPKTLAPIPIPIPASEMANP----KVFFDMTVGGAPAGRIVMELYKDA 187 +P P + + +PA +P +VFF T+G P R++ ++YK + Sbjct: 333 YPTQPCRFGKLLLLLPALRSISPSTIEEVFFKKTIGNVPITRLLSDMYKSS 383
>MOT8_HUMAN (P36021) Monocarboxylate transporter 8 (MCT 8) (X-linked| PEST-containing transporter) (MCT 7) Length = 613 Score = 30.0 bits (66), Expect = 5.4 Identities = 14/37 (37%), Positives = 20/37 (54%) Frame = +2 Query: 11 PKPEEIPIRAPEFPIPPKTLAPIPIPIPASEMANPKV 121 P+PE +P+ PE P P P P P+P E + +V Sbjct: 113 PEPEPVPVPPPE-PQPEPQPLPDPAPLPELEFESERV 148
>KS6B2_HUMAN (Q9UBS0) Ribosomal protein S6 kinase beta-2 (EC 2.7.11.1) (S6K2)| (70 kDa ribosomal protein S6 kinase 2) (p70-S6KB) (p70 ribosomal S6 kinase beta) (p70 S6Kbeta) (p70 S6 kinase beta) (S6K-beta) (p70-beta) (S6 kinase-related kinase) (SRK) (Serin Length = 482 Score = 30.0 bits (66), Expect = 5.4 Identities = 13/29 (44%), Positives = 18/29 (62%) Frame = +2 Query: 11 PKPEEIPIRAPEFPIPPKTLAPIPIPIPA 97 P+P E+P+ P PP T AP+PI P+ Sbjct: 440 PEPTELPLPPLLPPPPPSTTAPLPIRPPS 468
>TONB_YEREN (Q05740) Protein tonB| Length = 255 Score = 30.0 bits (66), Expect = 5.4 Identities = 15/36 (41%), Positives = 19/36 (52%) Frame = +2 Query: 11 PKPEEIPIRAPEFPIPPKTLAPIPIPIPASEMANPK 118 P+PE P E P P+ L P P+P+P E PK Sbjct: 75 PEPEPEPEPIDEAPPEPEVL-PEPVPVPIPEPVKPK 109
>TRPB2_THEMA (Q9WZ09) Tryptophan synthase beta chain 2 (EC 4.2.1.20)| Length = 422 Score = 30.0 bits (66), Expect = 5.4 Identities = 32/144 (22%), Positives = 53/144 (36%), Gaps = 18/144 (12%) Frame = +2 Query: 200 VENFRALCTGEKGVGKSGKPLHYKGSSFHRVIPDFMCQXXXXXXXXXXXXESIYGEK--- 370 +E + L T E G G+ G L Y G+ F + FM + +++G K Sbjct: 124 IEGVKRLVT-ETGAGQWGSALSYAGAKFGLEVKVFMVKVSYQQKPMRKYMMNLFGGKVTP 182 Query: 371 -------FADEKFVHKHTKPG--------ILSMANAGPNTNGSQFFICTVPCNWLDGKHV 505 F + PG L +A + PNT S + HV Sbjct: 183 SPSEETNFGRKILSEDPDNPGSLGIAISEALEVAVSDPNTKYSLGSVL---------NHV 233 Query: 506 VFGEVVEGMDVVKNIEKVGSRSGI 577 + + V G+++ K +E +G + I Sbjct: 234 LLHQTVIGLEIKKQLELIGEKPDI 257
>SELV_HUMAN (P59797) Selenoprotein V| Length = 346 Score = 29.6 bits (65), Expect = 7.1 Identities = 15/38 (39%), Positives = 21/38 (55%), Gaps = 4/38 (10%) Frame = +2 Query: 8 SPKPEEIPIRAP-EFPIPPKTLAP---IPIPIPASEMA 109 +P P +P+R P P P +TL P +P P PA +A Sbjct: 95 TPVPTPVPVRNPTPVPTPARTLTPPVRVPAPAPAQLLA 132
>POT2_ARATH (O22881) Potassium transporter 2 (AtPOT2) (AtKUP2) (AtKT2)| Length = 794 Score = 29.6 bits (65), Expect = 7.1 Identities = 14/31 (45%), Positives = 22/31 (70%), Gaps = 3/31 (9%) Frame = -3 Query: 447 LVLGPALAMERIPGLVCLWTNFSS---ANFS 364 L LGP+L + R+PG+ ++T+ +S ANFS Sbjct: 517 LALGPSLGISRVPGIGLVFTDLTSGIPANFS 547
>RAPH1_HUMAN (Q70E73) Ras-associated and pleckstrin homology domains-containing| protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein) Length = 1302 Score = 29.6 bits (65), Expect = 7.1 Identities = 13/33 (39%), Positives = 19/33 (57%), Gaps = 5/33 (15%) Frame = +2 Query: 14 KPEEIPIRAPEFPIPPKTLA-----PIPIPIPA 97 +P IP+ +P+FP PP + P P P+PA Sbjct: 957 QPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPA 989
>PDLI5_HUMAN (Q96HC4) PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like| PDZ and LIM domains protein) Length = 595 Score = 29.6 bits (65), Expect = 7.1 Identities = 13/32 (40%), Positives = 20/32 (62%) Frame = +2 Query: 2 SQSPKPEEIPIRAPEFPIPPKTLAPIPIPIPA 97 S +PKPE +P++ E P + + P+PI PA Sbjct: 84 SAAPKPEPVPVQKGE---PKEVVKPVPITSPA 112
>CYB2_YEAST (P00175) Cytochrome b2, mitochondrial precursor (EC 1.1.2.3)| (L-lactate dehydrogenase [Cytochrome]) (L-lactate ferricytochrome C oxidoreductase) (L-LCR) Length = 591 Score = 29.3 bits (64), Expect = 9.3 Identities = 17/42 (40%), Positives = 24/42 (57%), Gaps = 1/42 (2%) Frame = +2 Query: 167 MELYKDA-VPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHR 289 +E++ D V R + +ALC G KGVG G+P Y S + R Sbjct: 484 LEVFVDGGVRRGTDVLKALCLGAKGVG-LGRPFLYANSCYGR 524
>TRX2_MOUSE (O08550) Trithorax homolog 2 (WW domain-binding protein 7)| (Fragment) Length = 290 Score = 29.3 bits (64), Expect = 9.3 Identities = 15/38 (39%), Positives = 19/38 (50%) Frame = +2 Query: 2 SQSPKPEEIPIRAPEFPIPPKTLAPIPIPIPASEMANP 115 S SP P P+ P P PP L+P P P P + +P Sbjct: 58 STSPPPPASPLPPPVSPPPP--LSPPPYPAPEKQEESP 93
>GP1_CHLRE (Q9FPQ6) Vegetative cell wall protein gp1 precursor| (Hydroxyproline-rich glycoprotein 1) Length = 555 Score = 29.3 bits (64), Expect = 9.3 Identities = 16/38 (42%), Positives = 17/38 (44%) Frame = +2 Query: 8 SPKPEEIPIRAPEFPIPPKTLAPIPIPIPASEMANPKV 121 SP P P AP P PP P+P P PA P V Sbjct: 162 SPSPPVPPSPAPPSPTPPSPSPPVP-PSPAPPSPAPPV 198
>APG_ARATH (P40602) Anter-specific proline-rich protein APG precursor| Length = 534 Score = 29.3 bits (64), Expect = 9.3 Identities = 17/42 (40%), Positives = 19/42 (45%), Gaps = 3/42 (7%) Frame = +2 Query: 2 SQSPKPEEIPIRAPE---FPIPPKTLAPIPIPIPASEMANPK 118 S PKP+ P AP P PP P P+P PA PK Sbjct: 90 SPPPKPQPKPPPAPSPSPCPSPPPKPQPKPVPPPACPPTPPK 131
>MAP1A_RAT (P34926) Microtubule-associated protein 1A (MAP 1A) [Contains: MAP1| light chain LC2] Length = 2774 Score = 29.3 bits (64), Expect = 9.3 Identities = 30/101 (29%), Positives = 41/101 (40%), Gaps = 8/101 (7%) Frame = +2 Query: 23 EIPIRAP-EFPIPPKTLAPIPI-PIPASEMANPKVF------FDMTVGGAPAGRIVMELY 178 EIP P + P+PP L+P P P PA E P F +D V G EL Sbjct: 1807 EIPPWVPKDRPLPPAPLSPAPAPPTPAPEPHTPVPFSWGLAEYDSVVAAVQEG--AAELE 1864 Query: 179 KDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSSFHRVIPD 301 +++R +G G +G P SSF +P+ Sbjct: 1865 GGPYSPLGKDYRKAEGEREGEGGAGAP---DSSSFSPKVPE 1902
>MURG_GLOVI (Q7MBC4) UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide)| pyrophosphoryl-undecaprenol N-acetylglucosamine transferase (EC 2.4.1.227) (Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase) Length = 357 Score = 29.3 bits (64), Expect = 9.3 Identities = 21/83 (25%), Positives = 34/83 (40%), Gaps = 4/83 (4%) Frame = +2 Query: 29 PIRAPEFPIPPKTLAPIPIPIPASEMANPKVFFDMTVGGAPAGRIVMELYKDAVPRTVEN 208 P+R PEF I P L +P+P P+ + +GG+ R + ++ + P +E Sbjct: 161 PVR-PEFLISPNPLLDVPVP--------PEAPLIVVMGGSQGARAINQMVGECAPGWLER 211 Query: 209 ----FRALCTGEKGVGKSGKPLH 265 GE + G P H Sbjct: 212 GWWIVHLTGAGEYDAVREGTPDH 234
>BARX2_HUMAN (Q9UMQ3) Homeobox protein BarH-like 2| Length = 254 Score = 29.3 bits (64), Expect = 9.3 Identities = 14/34 (41%), Positives = 20/34 (58%) Frame = +2 Query: 2 SQSPKPEEIPIRAPEFPIPPKTLAPIPIPIPASE 103 +Q PK ++P+ E P PP+ L PIP+SE Sbjct: 221 AQEPKARDVPLEMAEPPDPPQEL-----PIPSSE 249 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 45,568,741 Number of Sequences: 219361 Number of extensions: 790240 Number of successful extensions: 5006 Number of sequences better than 10.0: 235 Number of HSP's better than 10.0 without gapping: 4094 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4659 length of database: 80,573,946 effective HSP length: 107 effective length of database: 57,102,319 effective search space used: 5367617986 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)