>C1TC_YEAST (P07245) C-1-tetrahydrofolate synthase, cytoplasmic (C1-THF|
           synthase) [Includes: Methylenetetrahydrofolate
           dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate
           cyclohydrolase (EC 3.5.4.9); Formyltetrahydrofolate
           synthetase (EC 6.3.4.3)]
          Length = 946

 Score =  150 bits (378), Expect = 3e-36
 Identities = 76/168 (45%), Positives = 105/168 (62%), Gaps = 1/168 (0%)
 Frame = +2

Query: 80  QIIDGKXXXXXXXXXXXXXXXXLSS-AHSIVPGLAVVIVGSRKDSQTYVQMKRKACAEVG 256
           Q++DGK                +        P LA++ VG+R DS TYV+MKRKA  E G
Sbjct: 4   QVLDGKACAQQFRSNIANEIKSIQGHVPGFAPNLAIIQVGNRPDSATYVRMKRKAAEEAG 63

Query: 257 IRSFDVDLPEDISEAALVAEVHRLNADPAVHGILVQLPLPKHINEEIILNQISIEKDVDG 436
           I +  + L E  +E  ++  V +LN DP  HGI+VQLPLP H++E+ I +++  EKDVDG
Sbjct: 64  IVANFIHLDESATEFEVLRYVDQLNEDPHTHGIIVQLPLPAHLDEDRITSRVLAEKDVDG 123

Query: 437 FHPLNIGKLAMKGRNPLFLPCTPKGCMELLSRSGVTVKGKHAVVVGRS 580
           F P NIG+L  K  +P FLPCTPKG +ELL ++ VT++G  +VV+GRS
Sbjct: 124 FGPTNIGELNKKNGHPFFLPCTPKGIIELLHKANVTIEGSRSVVIGRS 171

>FOLD_SALTI (Q60006) FolD bifunctional protein [Includes:|
           Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
           Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)]
          Length = 287

 Score =  143 bits (361), Expect = 3e-34
 Identities = 81/168 (48%), Positives = 99/168 (58%)
 Frame = +2

Query: 77  AQIIDGKXXXXXXXXXXXXXXXXLSSAHSIVPGLAVVIVGSRKDSQTYVQMKRKACAEVG 256
           A+IIDGK                  +A    PGLAVV+VGS   SQ YV  KRKAC EVG
Sbjct: 2   AKIIDGKTIAQQVRSEVAQKVQARVAAGLRAPGLAVVLVGSNPASQIYVASKRKACDEVG 61

Query: 257 IRSFDVDLPEDISEAALVAEVHRLNADPAVHGILVQLPLPKHINEEIILNQISIEKDVDG 436
             S   DLPE  SEA L+A +  LNAD  + GILVQLPLP  I+   +L +I+ +KDVDG
Sbjct: 62  FVSHSYDLPETTSEAELLALIDTLNADNTIDGILVQLPLPAGIDNVKVLERIAPDKDVDG 121

Query: 437 FHPLNIGKLAMKGRNPLFLPCTPKGCMELLSRSGVTVKGKHAVVVGRS 580
           FHP N+G+L    R P   PCTP+G + LL R  +   G +AVV+G S
Sbjct: 122 FHPYNVGRLCQ--RAPRLRPCTPRGIVTLLERYNIDTYGLNAVVIGAS 167

>FOLD_PHOPO (P51696) FolD bifunctional protein (PPDC) [Includes:|
           Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
           Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)]
          Length = 285

 Score =  143 bits (361), Expect = 3e-34
 Identities = 82/168 (48%), Positives = 97/168 (57%)
 Frame = +2

Query: 77  AQIIDGKXXXXXXXXXXXXXXXXLSSAHSIVPGLAVVIVGSRKDSQTYVQMKRKACAEVG 256
           AQIIDGK                 + A    PGLAVV+VG    SQ YV  KRKAC EVG
Sbjct: 3   AQIIDGKIISQTVRQEVAARVKARTDAGLRAPGLAVVLVGQDPASQIYVGSKRKACEEVG 62

Query: 257 IRSFDVDLPEDISEAALVAEVHRLNADPAVHGILVQLPLPKHINEEIILNQISIEKDVDG 436
             S   DLP   SE  L+  +  LN DP + GILVQLPLP  ++   IL +I  EKDVDG
Sbjct: 63  FISKSFDLPSSASEQQLLDLIDELNQDPTMDGILVQLPLPAGMDCTRILERIDPEKDVDG 122

Query: 437 FHPLNIGKLAMKGRNPLFLPCTPKGCMELLSRSGVTVKGKHAVVVGRS 580
           FHP N+G+L+   R P    CTPKG + LL R  + V+GKHAV+VG S
Sbjct: 123 FHPYNVGRLSQ--RIPKLRSCTPKGIITLLERYNIEVRGKHAVIVGAS 168

>FOLD_HAEIN (P44313) FolD bifunctional protein [Includes:|
           Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
           Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)]
          Length = 281

 Score =  143 bits (361), Expect = 3e-34
 Identities = 74/137 (54%), Positives = 94/137 (68%)
 Frame = +2

Query: 170 PGLAVVIVGSRKDSQTYVQMKRKACAEVGIRSFDVDLPEDISEAALVAEVHRLNADPAVH 349
           PGLAV++VG+   SQ YV  KRK+C EVGI S   DLPE  ++  L+A + +LNAD  + 
Sbjct: 33  PGLAVILVGADPASQIYVGNKRKSCEEVGILSKSYDLPETTTQNELLAIIDQLNADKNID 92

Query: 350 GILVQLPLPKHINEEIILNQISIEKDVDGFHPLNIGKLAMKGRNPLFLPCTPKGCMELLS 529
           GILVQLPLPK IN E I+ +I  +KDVDGFHP N+G+L    R P    CTP G M+LL 
Sbjct: 93  GILVQLPLPKQINAEAIIERIDPKKDVDGFHPYNVGRLCQ--RIPTLRACTPYGVMKLLE 150

Query: 530 RSGVTVKGKHAVVVGRS 580
            +G+ + GKHAV+VG S
Sbjct: 151 TTGIDLHGKHAVIVGAS 167

>FOLD_SALTY (P58688) FolD bifunctional protein [Includes:|
           Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
           Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)]
          Length = 287

 Score =  142 bits (359), Expect = 5e-34
 Identities = 81/168 (48%), Positives = 99/168 (58%)
 Frame = +2

Query: 77  AQIIDGKXXXXXXXXXXXXXXXXLSSAHSIVPGLAVVIVGSRKDSQTYVQMKRKACAEVG 256
           A+IIDGK                  +A    PGLAVV+VGS   SQ YV  KRKAC EVG
Sbjct: 2   AKIIDGKTIAQQVRSEVAQKVQARVAAGLRAPGLAVVLVGSNPASQIYVASKRKACDEVG 61

Query: 257 IRSFDVDLPEDISEAALVAEVHRLNADPAVHGILVQLPLPKHINEEIILNQISIEKDVDG 436
             S   DLPE  SEA L+A +  LNAD  + GILVQLPLP  I+   +L +I+ +KDVDG
Sbjct: 62  FVSRSYDLPETTSEAELLALIDTLNADNTIDGILVQLPLPAGIDNVKVLERIAPDKDVDG 121

Query: 437 FHPLNIGKLAMKGRNPLFLPCTPKGCMELLSRSGVTVKGKHAVVVGRS 580
           FHP N+G+L    R P   PCTP+G + LL R  +   G +AVV+G S
Sbjct: 122 FHPYNVGRLCQ--RAPRLRPCTPRGIVTLLERYNIDTYGLNAVVIGAS 167

>C1TM_YEAST (P09440) C-1-tetrahydrofolate synthase, mitochondrial precursor|
           (C1-THF synthase) [Includes: Methylenetetrahydrofolate
           dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate
           cyclohydrolase (EC 3.5.4.9); Formyltetrahydrofolate
           synthetase (EC 6.3.
          Length = 975

 Score =  142 bits (358), Expect = 7e-34
 Identities = 66/137 (48%), Positives = 94/137 (68%)
 Frame = +2

Query: 170 PGLAVVIVGSRKDSQTYVQMKRKACAEVGIRSFDVDLPEDISEAALVAEVHRLNADPAVH 349
           P L ++ VG+R DS TYV+MK KA  +  +      LP +I+E  L+ ++  +N D ++H
Sbjct: 67  PTLKIIQVGARPDSSTYVRMKLKASKDSNVDCIIEKLPAEITEVELLKKISDINDDDSIH 126

Query: 350 GILVQLPLPKHINEEIILNQISIEKDVDGFHPLNIGKLAMKGRNPLFLPCTPKGCMELLS 529
           G+L+QLPLP+H++E  I N +  +KDVDGFH  N G+LA KG  P F+PCTP GCM+LL 
Sbjct: 127 GLLIQLPLPRHLDETTITNAVDFKKDVDGFHRYNAGELAKKGGKPYFIPCTPYGCMKLLE 186

Query: 530 RSGVTVKGKHAVVVGRS 580
            + V + GK+AVV+GRS
Sbjct: 187 EAHVKLDGKNAVVLGRS 203

>FOLD_STRTR (P96050) FolD bifunctional protein [Includes:|
           Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
           Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)]
          Length = 284

 Score =  141 bits (356), Expect = 1e-33
 Identities = 79/169 (46%), Positives = 98/169 (57%)
 Frame = +2

Query: 74  MAQIIDGKXXXXXXXXXXXXXXXXLSSAHSIVPGLAVVIVGSRKDSQTYVQMKRKACAEV 253
           MA I+DGK                L     IVPGL V++VG    SQ YV+ K +A  + 
Sbjct: 1   MAIIMDGKALAVNMQEQLQEKVARLKEKEWIVPGLVVIMVGENPASQVYVRNKERAAKKA 60

Query: 254 GIRSFDVDLPEDISEAALVAEVHRLNADPAVHGILVQLPLPKHINEEIILNQISIEKDVD 433
           G  S  V+L E ISE  L+  + + N +P  HGILVQLPLP HINE  IL  I  +KDVD
Sbjct: 61  GFHSKTVNLSESISEEELIEVIEKYNQNPLFHGILVQLPLPNHINEMRILLAIDPKKDVD 120

Query: 434 GFHPLNIGKLAMKGRNPLFLPCTPKGCMELLSRSGVTVKGKHAVVVGRS 580
           GFHP+N G L   GR P  +PCTP G ME+L    V ++GK AV++GRS
Sbjct: 121 GFHPMNTGNL-WNGR-PQMVPCTPAGIMEILREYNVELEGKTAVIIGRS 167

>FOLD_CHLPN (Q9Z8K3) FolD bifunctional protein [Includes:|
           Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
           Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)]
          Length = 286

 Score =  140 bits (354), Expect = 2e-33
 Identities = 70/137 (51%), Positives = 97/137 (70%)
 Frame = +2

Query: 170 PGLAVVIVGSRKDSQTYVQMKRKACAEVGIRSFDVDLPEDISEAALVAEVHRLNADPAVH 349
           PGLAVV++G+   S+ YV MK K   E+GI S    LP D + ++++  + RLN DP++H
Sbjct: 27  PGLAVVLIGNDPASEVYVGMKVKKATEIGIISKAHKLPSDSTLSSVLKLIERLNQDPSIH 86

Query: 350 GILVQLPLPKHINEEIILNQISIEKDVDGFHPLNIGKLAMKGRNPLFLPCTPKGCMELLS 529
           GILVQLPLPKH++ E+IL  IS +KDVDG HP+N+GKL + G     LPCTP G +ELL+
Sbjct: 87  GILVQLPLPKHLDSEVILQAISPDKDVDGLHPVNMGKLLL-GNFDGLLPCTPAGIIELLN 145

Query: 530 RSGVTVKGKHAVVVGRS 580
              + ++G+HA +VGRS
Sbjct: 146 YYEIPLRGRHAAIVGRS 162

>FOLD_ECOLI (P24186) FolD bifunctional protein [Includes:|
           Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
           Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)]
          Length = 287

 Score =  140 bits (352), Expect = 3e-33
 Identities = 80/168 (47%), Positives = 97/168 (57%)
 Frame = +2

Query: 77  AQIIDGKXXXXXXXXXXXXXXXXLSSAHSIVPGLAVVIVGSRKDSQTYVQMKRKACAEVG 256
           A+IIDGK                  +A    PGLAVV+VGS   SQ YV  KRKAC EVG
Sbjct: 2   AKIIDGKTIAQQVRSEVAQKVQARIAAGLRAPGLAVVLVGSNPASQIYVASKRKACEEVG 61

Query: 257 IRSFDVDLPEDISEAALVAEVHRLNADPAVHGILVQLPLPKHINEEIILNQISIEKDVDG 436
             S   DLPE  SEA L+  +  LNAD  + GILVQLPLP  I+   +L +I  +KDVDG
Sbjct: 62  FVSRSYDLPETTSEAELLELIDTLNADNTIDGILVQLPLPAGIDNVKVLERIHPDKDVDG 121

Query: 437 FHPLNIGKLAMKGRNPLFLPCTPKGCMELLSRSGVTVKGKHAVVVGRS 580
           FHP N+G+L    R P   PCTP+G + LL R  +   G +AVV+G S
Sbjct: 122 FHPYNVGRLCQ--RAPRLRPCTPRGIVTLLERYNIDTFGLNAVVIGAS 167

>C1TC_MOUSE (Q922D8) C-1-tetrahydrofolate synthase, cytoplasmic (C1-THF|
           synthase) [Includes: Methylenetetrahydrofolate
           dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate
           cyclohydrolase (EC 3.5.4.9); Formyltetrahydrofolate
           synthetase (EC 6.3.4.3)]
          Length = 934

 Score =  137 bits (345), Expect = 2e-32
 Identities = 68/139 (48%), Positives = 93/139 (66%), Gaps = 2/139 (1%)
 Frame = +2

Query: 170 PGLAVVIVGSRKDSQTYVQMKRKACAEVGIRSFDVDLPEDISEAALVAEVHRLNADPAVH 349
           PGLA++ VG R DS  Y+ +K KA  E+GI++  + LP   +E+ ++  V  LN D +VH
Sbjct: 35  PGLAILQVGDRDDSNLYINVKLKAAEEIGIKATHIKLPRTSTESEVLKYVISLNEDASVH 94

Query: 350 GILVQLPLPKH--INEEIILNQISIEKDVDGFHPLNIGKLAMKGRNPLFLPCTPKGCMEL 523
           G +VQLPL     IN E ++N I+ EKDVDG   ++ GKLA    N  F+PCTPKGC+EL
Sbjct: 95  GFIVQLPLDSENSINTEAVINAIAPEKDVDGLTSVSAGKLARGDLNDCFIPCTPKGCLEL 154

Query: 524 LSRSGVTVKGKHAVVVGRS 580
           +  +GV + G+HAVVVGRS
Sbjct: 155 IKEAGVQIAGRHAVVVGRS 173

>C1TC_RAT (P27653) C-1-tetrahydrofolate synthase, cytoplasmic (C1-THF|
           synthase) [Includes: Methylenetetrahydrofolate
           dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate
           cyclohydrolase (EC 3.5.4.9); Formyltetrahydrofolate
           synthetase (EC 6.3.4.3)]
          Length = 934

 Score =  137 bits (344), Expect = 3e-32
 Identities = 68/139 (48%), Positives = 91/139 (65%), Gaps = 2/139 (1%)
 Frame = +2

Query: 170 PGLAVVIVGSRKDSQTYVQMKRKACAEVGIRSFDVDLPEDISEAALVAEVHRLNADPAVH 349
           PGLA++ VG R DS  Y+ +K KA  E+GI++  + LP   +E+ ++  V  LN D  VH
Sbjct: 35  PGLAILQVGDRDDSNLYINVKLKAAQEIGIKATHIKLPRTSTESEVLKYVISLNEDATVH 94

Query: 350 GILVQLPLPKH--INEEIILNQISIEKDVDGFHPLNIGKLAMKGRNPLFLPCTPKGCMEL 523
           G +VQLPL     IN E ++N I+ EKDVDG   +N GKLA       F+PCTPKGC+EL
Sbjct: 95  GFIVQLPLDSENSINTEAVINAIAPEKDVDGLTSINAGKLARGDLKDCFIPCTPKGCLEL 154

Query: 524 LSRSGVTVKGKHAVVVGRS 580
           +  +GV + G+HAVVVGRS
Sbjct: 155 IKETGVQIAGRHAVVVGRS 173

>C1TC_HUMAN (P11586) C-1-tetrahydrofolate synthase, cytoplasmic (C1-THF|
           synthase) [Includes: Methylenetetrahydrofolate
           dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate
           cyclohydrolase (EC 3.5.4.9); Formyltetrahydrofolate
           synthetase (EC 6.3.4.3)]
          Length = 934

 Score =  136 bits (343), Expect = 4e-32
 Identities = 72/171 (42%), Positives = 100/171 (58%), Gaps = 3/171 (1%)
 Frame = +2

Query: 77  AQIIDGKXXXXXXXXXXXXXXXXLSS-AHSIVPGLAVVIVGSRKDSQTYVQMKRKACAEV 253
           A+I++GK                L        P LA++ VG+R DS  Y+ +K KA  E+
Sbjct: 3   AEILNGKEISAQIRARLKNQVTQLKEQVPGFTPRLAILQVGNRDDSNLYINVKLKAAEEI 62

Query: 254 GIRSFDVDLPEDISEAALVAEVHRLNADPAVHGILVQLPLPKH--INEEIILNQISIEKD 427
           GI++  + LP   +E+ ++  +  LN D  VHG LVQLPL     IN E ++N I+ EKD
Sbjct: 63  GIKATHIKLPRTTTESEVMKYITSLNEDSTVHGFLVQLPLDSENSINTEEVINAIAPEKD 122

Query: 428 VDGFHPLNIGKLAMKGRNPLFLPCTPKGCMELLSRSGVTVKGKHAVVVGRS 580
           VDG   +N G+LA    N  F+PCTPKGC+EL+  +GV + G+HAVVVGRS
Sbjct: 123 VDGLTSINAGRLARGDLNDCFIPCTPKGCLELIKETGVPIAGRHAVVVGRS 173

>FOLD_BACSU (P54382) FolD bifunctional protein [Includes:|
           Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
           Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)]
          Length = 283

 Score =  135 bits (341), Expect = 6e-32
 Identities = 73/169 (43%), Positives = 104/169 (61%), Gaps = 1/169 (0%)
 Frame = +2

Query: 77  AQIIDGKXXXXXXXXXXXXXXXXLSSAHSIVPGLAVVIVGSRKDSQTYVQMKRKACAEVG 256
           A IIDGK                L     + PGLAV+++G    S +YV+ K+KA   +G
Sbjct: 3   ATIIDGKETAREKREQLAKEVEELKK-QGVTPGLAVILIGDDPASHSYVRGKKKAAETMG 61

Query: 257 IRSFDVD-LPEDISEAALVAEVHRLNADPAVHGILVQLPLPKHINEEIILNQISIEKDVD 433
           + +F +D     ++EA L++ + + N DP  HGILVQLPLP HI+E+ ++ +IS +KDVD
Sbjct: 62  M-NFKLDQFDSSLTEAELLSIIDQYNQDPEFHGILVQLPLPDHISEKAVIERISPDKDVD 120

Query: 434 GFHPLNIGKLAMKGRNPLFLPCTPKGCMELLSRSGVTVKGKHAVVVGRS 580
           GFHPLN+GK+ +      FLPCTP G +ELL ++ + + GK  VVVGRS
Sbjct: 121 GFHPLNVGKMLL--GEDTFLPCTPHGIVELLKKTNIDLSGKEVVVVGRS 167

>C1TC_DROME (O96553) C-1-tetrahydrofolate synthase, cytoplasmic (C1-THF|
           synthase) [Includes: Methylenetetrahydrofolate
           dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate
           cyclohydrolase (EC 3.5.4.9); Formyltetrahydrofolate
           synthetase (EC 6.3.4.3)]
          Length = 968

 Score =  134 bits (338), Expect = 1e-31
 Identities = 72/140 (51%), Positives = 95/140 (67%), Gaps = 2/140 (1%)
 Frame = +2

Query: 167 VPGLAVVIVGSRKDSQTYVQMKRKACAEVGIRSFDVDLPEDISEAALVAEVHRLNADPAV 346
           VPGL +V VG R+DS  Y++MK KA  E+GI +  V LP  I+E  L+ +++ LN DP V
Sbjct: 69  VPGLRIVQVGGREDSNVYIRMKIKAATEIGIDAAHVQLPRSITEVELLDKINDLNEDPRV 128

Query: 347 HGILVQLPL--PKHINEEIILNQISIEKDVDGFHPLNIGKLAMKGRNPLFLPCTPKGCME 520
           HGI+VQ+PL     I+   I + +S EKDVDG H +N G+LA+ G    FLPCTP GC+E
Sbjct: 129 HGIIVQMPLDCDTPIDSHRITDAVSPEKDVDGLHTVNEGRLAI-GDLGGFLPCTPWGCLE 187

Query: 521 LLSRSGVTVKGKHAVVVGRS 580
           L+ RSGV + G  AVV+GRS
Sbjct: 188 LIRRSGVEIAGARAVVLGRS 207

>FOLD_CHLTR (O84081) FolD bifunctional protein [Includes:|
           Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
           Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)]
          Length = 287

 Score =  133 bits (334), Expect = 4e-31
 Identities = 66/142 (46%), Positives = 95/142 (66%)
 Frame = +2

Query: 155 AHSIVPGLAVVIVGSRKDSQTYVQMKRKACAEVGIRSFDVDLPEDISEAALVAEVHRLNA 334
           A S  PGLAVV++G+   S+ YV MK K   ++G+ S     P D + + ++A +H+LN 
Sbjct: 22  ACSKAPGLAVVLIGNNPASEIYVNMKIKRATDLGMVSKSYRKPSDATLSDILALIHQLNN 81

Query: 335 DPAVHGILVQLPLPKHINEEIILNQISIEKDVDGFHPLNIGKLAMKGRNPLFLPCTPKGC 514
           D  +HGILVQLPLPKH++ + IL+ I+ +KDVDG HP+N+GKL + G    F+PCTP G 
Sbjct: 82  DENIHGILVQLPLPKHLDAQAILSTITPDKDVDGLHPVNVGKLLL-GETDGFIPCTPAGI 140

Query: 515 MELLSRSGVTVKGKHAVVVGRS 580
           +EL     + + GKH V++GRS
Sbjct: 141 VELCKYYEIPLHGKHVVILGRS 162

>FOLD_CHLMU (Q9PKW1) FolD bifunctional protein [Includes:|
           Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
           Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)]
          Length = 287

 Score =  131 bits (329), Expect = 2e-30
 Identities = 63/137 (45%), Positives = 91/137 (66%)
 Frame = +2

Query: 170 PGLAVVIVGSRKDSQTYVQMKRKACAEVGIRSFDVDLPEDISEAALVAEVHRLNADPAVH 349
           PGLAVV++G+   S+ YV MK K   ++G+ S     P D + + +++ +H LN D  +H
Sbjct: 27  PGLAVVLIGNNPASEIYVNMKVKRARDLGMISRSYRKPSDATLSDILSLIHELNCDENIH 86

Query: 350 GILVQLPLPKHINEEIILNQISIEKDVDGFHPLNIGKLAMKGRNPLFLPCTPKGCMELLS 529
           G+LVQLPLPKH++ + IL+ IS  KDVDG HP+N+GKL + G    F+PCTP G +EL  
Sbjct: 87  GVLVQLPLPKHLDTQTILSSISPNKDVDGLHPVNMGKLLL-GETDGFIPCTPSGIVELFK 145

Query: 530 RSGVTVKGKHAVVVGRS 580
              + + GKH V++GRS
Sbjct: 146 YYEIPLYGKHVVILGRS 162

>C1TC_SPOFR (Q27772) C-1-tetrahydrofolate synthase, cytoplasmic (C1-THF|
           synthase) [Includes: Methylenetetrahydrofolate
           dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate
           cyclohydrolase (EC 3.5.4.9); Formyltetrahydrofolate
           synthetase (EC 6.3.4.3)]
          Length = 933

 Score =  124 bits (312), Expect = 1e-28
 Identities = 63/137 (45%), Positives = 92/137 (67%), Gaps = 2/137 (1%)
 Frame = +2

Query: 176 LAVVIVGSRKDSQTYVQMKRKACAEVGIRSFDVDLPEDISEAALVAEVHRLNADPAVHGI 355
           LA+V VG R+DS  Y++MK +A   +GI +  + LP DI+E  L+A +  LN  P VHGI
Sbjct: 37  LAIVQVGGREDSNVYIRMKLRAAENIGITAEHIQLPRDITETELLANITSLNESPYVHGI 96

Query: 356 LVQLPLPK--HINEEIILNQISIEKDVDGFHPLNIGKLAMKGRNPLFLPCTPKGCMELLS 529
           +VQ+PL     I+   I + +S +KDVDG + +N G++ + G    F+PCTP GC+EL+ 
Sbjct: 97  IVQMPLDSVHPIDSHAITDAVSPDKDVDGLNTINEGRVRV-GDLSGFIPCTPAGCVELIK 155

Query: 530 RSGVTVKGKHAVVVGRS 580
           R+GVT+ GK+ VV+GRS
Sbjct: 156 RTGVTIAGKNVVVLGRS 172

>FOLD_HELPY (P56467) FolD bifunctional protein [Includes:|
           Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
           Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)]
          Length = 290

 Score =  124 bits (310), Expect = 3e-28
 Identities = 68/138 (49%), Positives = 89/138 (64%), Gaps = 1/138 (0%)
 Frame = +2

Query: 170 PGLAVVIVGSRKDSQTYVQMKRKACAEVGIRSFDVD-LPEDISEAALVAEVHRLNADPAV 346
           P LAV++VG    S TYV MK KAC  VG+  FD+  L E+I+EA L++ +   N D  +
Sbjct: 37  PKLAVILVGKDPASITYVNMKIKACERVGM-DFDLKTLQENITEAKLLSLIKDYNTDQNI 95

Query: 347 HGILVQLPLPKHINEEIILNQISIEKDVDGFHPLNIGKLAMKGRNPLFLPCTPKGCMELL 526
            G+LVQLPLP+HI+ ++IL  I   KDVDGFHPLNIGKL  +  +  FLP TP G M LL
Sbjct: 96  SGVLVQLPLPRHIDTKMILEAIDPNKDVDGFHPLNIGKLCTQKES--FLPATPMGVMRLL 153

Query: 527 SRSGVTVKGKHAVVVGRS 580
               + +KGK   ++G S
Sbjct: 154 EHYHIEIKGKDVAIIGAS 171

>MTDC_DROME (Q04448) Bifunctional methylenetetrahydrofolate|
           dehydrogenase/cyclohydrolase, mitochondrial precursor
           (DNMDMC) [Includes: NAD-dependent
           methylenetetrahydrofolate dehydrogenase (EC 1.5.1.15);
           Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)
          Length = 309

 Score =  122 bits (306), Expect = 7e-28
 Identities = 72/169 (42%), Positives = 92/169 (54%)
 Frame = +2

Query: 74  MAQIIDGKXXXXXXXXXXXXXXXXLSSAHSIVPGLAVVIVGSRKDSQTYVQMKRKACAEV 253
           MAQIIDGK                + +A    P L  VIVG    S+ YV  K  AC EV
Sbjct: 7   MAQIIDGKAIAQEVRTQLAHELKGMEAAGYPKPHLTAVIVGEDPASEKYVANKMVACREV 66

Query: 254 GIRSFDVDLPEDISEAALVAEVHRLNADPAVHGILVQLPLPKHINEEIILNQISIEKDVD 433
           GI S    LP   ++  L+  +  LN DP V GILVQLP+P+HINE  I N + ++KDVD
Sbjct: 67  GISSETKRLPASTTQEELLQLIADLNKDPQVTGILVQLPVPEHINERTICNAVDVDKDVD 126

Query: 434 GFHPLNIGKLAMKGRNPLFLPCTPKGCMELLSRSGVTVKGKHAVVVGRS 580
           GF+ +NIG+ A+       +P TP G   LL    +   G++AVVVGRS
Sbjct: 127 GFNEVNIGRTALD--MEANIPATPLGVKRLLEHMKIETLGRNAVVVGRS 173

>MTDC_MOUSE (P18155) Bifunctional methylenetetrahydrofolate|
           dehydrogenase/cyclohydrolase, mitochondrial precursor
           [Includes: NAD-dependent methylenetetrahydrofolate
           dehydrogenase (EC 1.5.1.15); Methenyltetrahydrofolate
           cyclohydrolase (EC 3.5.4.9)]
          Length = 350

 Score =  121 bits (304), Expect = 1e-27
 Identities = 61/137 (44%), Positives = 88/137 (64%)
 Frame = +2

Query: 170 PGLAVVIVGSRKDSQTYVQMKRKACAEVGIRSFDVDLPEDISEAALVAEVHRLNADPAVH 349
           P L+V++VG    S +YV  K +A AEVGI S  +  P  +SE  L+  + +LN D  V 
Sbjct: 68  PHLSVILVGDNPASHSYVLNKTRAAAEVGINSETIVKPASVSEEELLNSIRKLNNDENVD 127

Query: 350 GILVQLPLPKHINEEIILNQISIEKDVDGFHPLNIGKLAMKGRNPLFLPCTPKGCMELLS 529
           G+LVQLPLP+HI+E  + N +S +KDVDGFH +N+G++ +   +   LP TP G  E++ 
Sbjct: 128 GLLVQLPLPEHIDERKVCNAVSPDKDVDGFHVINVGRMCLDQYS--MLPATPWGVWEIIK 185

Query: 530 RSGVTVKGKHAVVVGRS 580
           R+G+   GK+ VV GRS
Sbjct: 186 RTGIPTLGKNVVVAGRS 202

>FOLD_HELPJ (Q9ZLQ4) FolD bifunctional protein [Includes:|
           Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
           Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)]
          Length = 290

 Score =  120 bits (302), Expect = 2e-27
 Identities = 68/138 (49%), Positives = 88/138 (63%), Gaps = 1/138 (0%)
 Frame = +2

Query: 170 PGLAVVIVGSRKDSQTYVQMKRKACAEVGIRSFDVD-LPEDISEAALVAEVHRLNADPAV 346
           P LAV++VG    S TYV MK KAC  VG+  FD+  L E+I+EA L++ +   N D  +
Sbjct: 37  PKLAVILVGKDPASITYVNMKIKACQRVGM-DFDLKTLKENITEAELLSLIKDYNTDQNI 95

Query: 347 HGILVQLPLPKHINEEIILNQISIEKDVDGFHPLNIGKLAMKGRNPLFLPCTPKGCMELL 526
            GILVQLPLP+ I+ ++IL  I   KDVDGFHPLNIGKL  +  +  FLP TP G M LL
Sbjct: 96  SGILVQLPLPRSIDTKMILEAIDPNKDVDGFHPLNIGKLCTQKES--FLPATPMGVMRLL 153

Query: 527 SRSGVTVKGKHAVVVGRS 580
               + +KGK   ++G S
Sbjct: 154 EHYHIEIKGKDVAIIGAS 171

>MTDC_HUMAN (P13995) Bifunctional methylenetetrahydrofolate|
           dehydrogenase/cyclohydrolase, mitochondrial precursor
           [Includes: NAD-dependent methylenetetrahydrofolate
           dehydrogenase (EC 1.5.1.15); Methenyltetrahydrofolate
           cyclohydrolase (EC 3.5.4.9)]
          Length = 344

 Score =  119 bits (297), Expect = 8e-27
 Identities = 62/137 (45%), Positives = 88/137 (64%)
 Frame = +2

Query: 170 PGLAVVIVGSRKDSQTYVQMKRKACAEVGIRSFDVDLPEDISEAALVAEVHRLNADPAVH 349
           P L+V++VG    S +YV  K +A A VGI S  +  P  ISE  L+  +++LN D  V 
Sbjct: 62  PHLSVILVGENPASHSYVLNKTRAAAVVGINSETIMKPASISEEELLNLINKLNNDDNVD 121

Query: 350 GILVQLPLPKHINEEIILNQISIEKDVDGFHPLNIGKLAMKGRNPLFLPCTPKGCMELLS 529
           G+LVQLPLP+HI+E  I N +S +KDVDGFH +N+G++ +   +   LP TP G  E++ 
Sbjct: 122 GLLVQLPLPEHIDERRICNAVSPDKDVDGFHVINVGRMCLDQYS--MLPATPWGVWEIIK 179

Query: 530 RSGVTVKGKHAVVVGRS 580
           R+G+   GK+ VV GRS
Sbjct: 180 RTGIPTLGKNVVVAGRS 196

>MTDC_CHICK (Q5ZKA5) Bifunctional methylenetetrahydrofolate|
           dehydrogenase/cyclohydrolase, mitochondrial precursor
           [Includes: NAD-dependent methylenetetrahydrofolate
           dehydrogenase (EC 1.5.1.15); Methenyltetrahydrofolate
           cyclohydrolase (EC 3.5.4.9)]
          Length = 337

 Score =  118 bits (295), Expect = 1e-26
 Identities = 62/137 (45%), Positives = 88/137 (64%)
 Frame = +2

Query: 170 PGLAVVIVGSRKDSQTYVQMKRKACAEVGIRSFDVDLPEDISEAALVAEVHRLNADPAVH 349
           P L+VV+VG    S +YV  K KA A+VGI S  +  P  I+E  L+  + +LN D  V 
Sbjct: 63  PHLSVVLVGENPASHSYVLNKTKAAADVGISSETILKPASITEEELLDLISKLNNDANVD 122

Query: 350 GILVQLPLPKHINEEIILNQISIEKDVDGFHPLNIGKLAMKGRNPLFLPCTPKGCMELLS 529
           G+LVQLPLP+HI+E  I N ++ +KDVDGFH +N+G++ +   +   LP TP G  E++ 
Sbjct: 123 GLLVQLPLPEHIDERKICNAVTPDKDVDGFHVINVGRMCLDQYS--MLPATPWGVWEIIK 180

Query: 530 RSGVTVKGKHAVVVGRS 580
           R+G+   GK+ VV GRS
Sbjct: 181 RTGIPTLGKNVVVAGRS 197

>FOLD_BUCBP (Q89A92) FolD bifunctional protein [Includes:|
           Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
           Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)]
          Length = 287

 Score =  117 bits (293), Expect = 2e-26
 Identities = 59/137 (43%), Positives = 85/137 (62%)
 Frame = +2

Query: 170 PGLAVVIVGSRKDSQTYVQMKRKACAEVGIRSFDVDLPEDISEAALVAEVHRLNADPAVH 349
           PGLAV+++GS   S  YV+ KR  C +VG  S      ++I E+ ++  +++LN D  + 
Sbjct: 34  PGLAVILIGSNSASTIYVKKKRFMCEQVGFISKFWKFSKNIQESKILNLIYKLNYDTTID 93

Query: 350 GILVQLPLPKHINEEIILNQISIEKDVDGFHPLNIGKLAMKGRNPLFLPCTPKGCMELLS 529
           GILVQLP+P +IN + + + I   KDVDGFHP NIG L  K  +P   PCTP G + +L 
Sbjct: 94  GILVQLPIPPNINNQKLFSSIIPTKDVDGFHPYNIGSLCQK--SPYLRPCTPFGIITMLK 151

Query: 530 RSGVTVKGKHAVVVGRS 580
              + ++G HAVV+G S
Sbjct: 152 HYKIKIRGLHAVVIGAS 168

>FOLD_RICPR (Q9ZD32) FolD bifunctional protein [Includes:|
           Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
           Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)]
          Length = 286

 Score =  114 bits (286), Expect = 2e-25
 Identities = 65/166 (39%), Positives = 89/166 (53%)
 Frame = +2

Query: 83  IIDGKXXXXXXXXXXXXXXXXLSSAHSIVPGLAVVIVGSRKDSQTYVQMKRKACAEVGIR 262
           IIDGK                        P LA+V+VG    S  YV+ K K   +VGI 
Sbjct: 5   IIDGKALANEILADLKLEIQGFKEKTKTSPKLAIVLVGDNPASMIYVKNKIKNAHQVGID 64

Query: 263 SFDVDLPEDISEAALVAEVHRLNADPAVHGILVQLPLPKHINEEIILNQISIEKDVDGFH 442
           +  V+L  +I    L+ +++ LN D  + GI+VQLPLP  I+E  IL+ +   KD DGFH
Sbjct: 65  TLLVNLSTNIYTDDLILKINELNLDKGISGIIVQLPLPSSIDENKILSAVLPSKDSDGFH 124

Query: 443 PLNIGKLAMKGRNPLFLPCTPKGCMELLSRSGVTVKGKHAVVVGRS 580
           PLN+G L   G N  F+PCT  GC+ ++ +    + GK AV+VGRS
Sbjct: 125 PLNVGYL-HSGINQGFIPCTALGCLAVIKKYAPNLNGKDAVIVGRS 169

>FOLD_RICCN (Q92HY4) FolD bifunctional protein [Includes:|
           Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
           Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)]
          Length = 288

 Score =  114 bits (286), Expect = 2e-25
 Identities = 63/169 (37%), Positives = 95/169 (56%)
 Frame = +2

Query: 74  MAQIIDGKXXXXXXXXXXXXXXXXLSSAHSIVPGLAVVIVGSRKDSQTYVQMKRKACAEV 253
           M  IIDGK                L+S  +  P LA+V+VG    S  YV+ K K   ++
Sbjct: 1   MNNIIDGKALANEILADLKLEIQELTSQTNASPKLAIVLVGDNPASIIYVRHKIKNAHKI 60

Query: 254 GIRSFDVDLPEDISEAALVAEVHRLNADPAVHGILVQLPLPKHINEEIILNQISIEKDVD 433
           GI +  ++L   I    L+++++ LN D  + GI+VQLPLP  I++  IL+ +S  KD+D
Sbjct: 61  GIYTLLINLSATIHTNDLISKINELNLDNEISGIIVQLPLPSSIDKNKILSAVSPSKDID 120

Query: 434 GFHPLNIGKLAMKGRNPLFLPCTPKGCMELLSRSGVTVKGKHAVVVGRS 580
           GFHPLN+G L   G +  F+PCT  GC+  + +    + GK+ V++GRS
Sbjct: 121 GFHPLNVGYL-HSGISQGFIPCTALGCLAAIKKYEPNLTGKNVVIIGRS 168

>FOLD_BUCAI (P57557) FolD bifunctional protein [Includes:|
           Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
           Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)]
          Length = 285

 Score =  114 bits (285), Expect = 2e-25
 Identities = 60/138 (43%), Positives = 84/138 (60%)
 Frame = +2

Query: 167 VPGLAVVIVGSRKDSQTYVQMKRKACAEVGIRSFDVDLPEDISEAALVAEVHRLNADPAV 346
           +PGLA+++VG+   SQ YV  K+ +C  VG  S   +LP +I+E  ++  + +LN +  +
Sbjct: 33  IPGLAMILVGNHIPSQIYVNKKKISCKNVGFFSECWNLPSNINEKEILNIISKLNENKNI 92

Query: 347 HGILVQLPLPKHINEEIILNQISIEKDVDGFHPLNIGKLAMKGRNPLFLPCTPKGCMELL 526
            GIL+QLPLP  IN   IL+ I  +KDVDGFHP N G L    R P    CTPKG + +L
Sbjct: 93  DGILIQLPLPPQINHMKILSSIVPDKDVDGFHPYNTGSLCQ--RTPKLRACTPKGIITML 150

Query: 527 SRSGVTVKGKHAVVVGRS 580
             + +   G HAV+VG S
Sbjct: 151 KYNKIKTHGLHAVMVGAS 168

>FOLD_BUCAP (Q8K979) FolD bifunctional protein [Includes:|
           Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
           Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)]
          Length = 285

 Score =  108 bits (271), Expect = 8e-24
 Identities = 57/138 (41%), Positives = 82/138 (59%)
 Frame = +2

Query: 167 VPGLAVVIVGSRKDSQTYVQMKRKACAEVGIRSFDVDLPEDISEAALVAEVHRLNADPAV 346
           +PGLAV+++G    S+ YV+ K   C +VG  S     P ++ E  ++  + +LN +  +
Sbjct: 33  IPGLAVILIGKNPASEIYVKRKISVCKKVGFISKYWSFPINVDEKDILNLIEKLNNNINI 92

Query: 347 HGILVQLPLPKHINEEIILNQISIEKDVDGFHPLNIGKLAMKGRNPLFLPCTPKGCMELL 526
            GILVQLP+PK IN   I + I  +KDVDGFHP N G L    RNP    CTPKG + +L
Sbjct: 93  DGILVQLPIPKQINYYKIFSSIRPDKDVDGFHPYNTGSLCQ--RNPTLRACTPKGIITML 150

Query: 527 SRSGVTVKGKHAVVVGRS 580
           + + +   G +AV+VG S
Sbjct: 151 NYTKIKTHGLNAVMVGAS 168

>FOLD_THEAC (Q05213) Probable folD bifunctional protein [Includes:|
           Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
           Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)]
          Length = 276

 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 39/138 (28%), Positives = 71/138 (51%), Gaps = 5/138 (3%)
 Frame = +2

Query: 170 PGLAVVIVGSRKDSQTYVQMKRKACAEVGIRSFDVDLPEDISEAALVAEVHRLNADPAVH 349
           P L ++ +G  + +  Y + K +   ++GI + D++  +DIS   L+  +  L  DP ++
Sbjct: 28  PSLKLIQIGDNEAASIYARAKIRRGKKIGI-AVDLEKYDDISMKDLLKRIDDLAKDPQIN 86

Query: 350 GILVQLPLPKHINEEIILNQISIEKDVDGFHPLNIGKLAMKGRNPLFLPCTPKGCMELLS 529
           GI+++ PLPK  +   I+  I   KDVD   P N G +A+       +P TP+  ++++ 
Sbjct: 87  GIMIENPLPKGFDYYEIVRNIPYYKDVDALSPYNQGLIAL--NREFLVPATPRAVIDIMD 144

Query: 530 RSG-----VTVKGKHAVV 568
             G     VT+  +  VV
Sbjct: 145 YYGYHENTVTIVNRSPVV 162

>FOLD_MYCGE (P47259) FolD bifunctional protein [Includes:|
           Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
           Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)]
          Length = 273

 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 36/133 (27%), Positives = 65/133 (48%)
 Frame = +2

Query: 176 LAVVIVGSRKDSQTYVQMKRKACAEVGIRSFDVDLPEDISEAALVAEVHRLNADPAVHGI 355
           L ++       S ++++ K  AC  VG +S  + L   I++A L+ ++  LN D  V GI
Sbjct: 26  LVIIQANDDDSSDSFIKQKLIACNTVGAKSELIKLSNQITQAELIEKIISLNHDVNVTGI 85

Query: 356 LVQLPLPKHINEEIILNQISIEKDVDGFHPLNIGKLAMKGRNPLFLPCTPKGCMELLSRS 535
           ++QLP+  H+++  +L  I+  KDVDG    ++ ++          PC  +  + L    
Sbjct: 86  ILQLPVYPHLDKNSLLEAINPLKDVDGLTTNHLAEIK---------PCIVEAIITLKELF 136

Query: 536 GVTVKGKHAVVVG 574
            +    +  VVVG
Sbjct: 137 NLEFNNQKIVVVG 149

>FOLD_MYCPN (P75096) FolD bifunctional protein [Includes:|
           Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
           Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)]
          Length = 269

 Score = 56.6 bits (135), Expect = 5e-08
 Identities = 29/86 (33%), Positives = 50/86 (58%), Gaps = 2/86 (2%)
 Frame = +2

Query: 182 VVIVGSRKD--SQTYVQMKRKACAEVGIRSFDVDLPEDISEAALVAEVHRLNADPAVHGI 355
           +VI+ +  D  S  +++ K  AC  +G +S  +   E ++E  L+ ++ +LN DP V GI
Sbjct: 26  LVILQTNNDVSSDAFIRQKMNACNTLGAQSELIKYHESVTEKELLEKIQQLNTDPEVTGI 85

Query: 356 LVQLPLPKHINEEIILNQISIEKDVD 433
           ++QLP+  H+ +  +L  I   KDVD
Sbjct: 86  ILQLPVYPHLKQNKLLKAIDPYKDVD 111

>MTD1_YEAST (Q02046) Methylenetetrahydrofolate dehydrogenase [NAD+] (EC|
           1.5.1.15)
          Length = 320

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 37/153 (24%), Positives = 69/153 (45%), Gaps = 16/153 (10%)
 Frame = +2

Query: 170 PGLAVVIVGSRKDSQTYVQMKRKACAEVGIRSFDVDLPEDISEAALVAEVHRLNADPAVH 349
           P L   +  +   ++ Y    +K    +G R +D+ + ED  +  L   + + N D +V+
Sbjct: 37  PLLVGFLANNDPAAKMYATWTQKTSESMGFR-YDLRVIED--KDFLEEAIIQANGDDSVN 93

Query: 350 GILVQLPLPKHINEEIILNQISIEKDVDGFHPL-------NIGKLAMKGRNPLFLPCTPK 508
           GI+V  P+  +  ++ +   +  EKDV+G + +       N+  L  + R    LPCTP 
Sbjct: 94  GIMVYFPVFGNAQDQYLQQVVCKEKDVEGLNHVYYQNLYHNVRYLDKENRLKSILPCTPL 153

Query: 509 GCMELLS---------RSGVTVKGKHAVVVGRS 580
             +++L            G  + GK  +V+ RS
Sbjct: 154 AIVKILEFLKIYNNLLPEGNRLYGKKCIVINRS 186

>PRMA_RHILO (Q98KD0) Ribosomal protein L11 methyltransferase (EC 2.1.1.-) (L11|
           Mtase)
          Length = 290

 Score = 33.1 bits (74), Expect = 0.59
 Identities = 19/73 (26%), Positives = 35/73 (47%)
 Frame = +2

Query: 257 IRSFDVDLPEDISEAALVAEVHRLNADPAVHGILVQLPLPKHINEEIILNQISIEKDVDG 436
           I   +VD  +DI E +L A+      +  V  IL  L L K +  E++ +   + + ++G
Sbjct: 33  IAVLEVDEDQDIHEVSLYADGDVDTVEARVKDILAGLALSKPVEREVLPDIDWVARSLEG 92

Query: 437 FHPLNIGKLAMKG 475
             P+  G+  + G
Sbjct: 93  LKPVRAGRFFVHG 105

>PHOSP_BRSVA (P33454) Phosphoprotein (Protein P)|
          Length = 241

 Score = 30.0 bits (66), Expect = 5.0
 Identities = 22/87 (25%), Positives = 37/87 (42%)
 Frame = +2

Query: 179 AVVIVGSRKDSQTYVQMKRKACAEVGIRSFDVDLPEDISEAALVAEVHRLNADPAVHGIL 358
           A   + S K   T  +  RK  + + + S D++LP+   E+ + +  H +N         
Sbjct: 17  ATKFLESLKGKFTSSKDSRKKDSIISVNSIDIELPK---ESPITSTNHNINQ-------- 65

Query: 359 VQLPLPKHINEEIILNQISIEKDVDGF 439
                P  IN+ I  NQ+ I K +  F
Sbjct: 66  -----PSEINDTIAANQVHIRKPLVSF 87

>METK_PINBN (P50300) S-adenosylmethionine synthetase (EC 2.5.1.6) (Methionine|
           adenosyltransferase) (AdoMet synthetase)
          Length = 393

 Score = 30.0 bits (66), Expect = 5.0
 Identities = 17/51 (33%), Positives = 23/51 (45%)
 Frame = +2

Query: 218 YVQMKRKACAEVGIRSFDVDLPEDISEAALVAEVHRLNADPAVHGILVQLP 370
           Y Q+ RK C E+G  S DV L  D  +  +  E    +    VHG   + P
Sbjct: 65  YEQIVRKTCREIGFISDDVGLDADHCKVLVNIEQQSPDIAQGVHGHFTKRP 115

>TMEM5_HUMAN (Q9Y2B1) Transmembrane protein 5|
          Length = 443

 Score = 29.6 bits (65), Expect = 6.5
 Identities = 20/62 (32%), Positives = 29/62 (46%), Gaps = 2/62 (3%)
 Frame = +1

Query: 394 NYIKPDLH*ERCRWFSSFEHWQAR--NERQKSTVPTLYPKGLHGAPVTQWSHCKRKARSC 567
           N +K D + + C W S+ EHWQ +  NE  K+    L    L   PV   + C R   +C
Sbjct: 287 NILKKDGNDKLC-WVSAREHWQPQETNESLKNYQDALLQSDLTLCPVGVNTECYRIYEAC 345

Query: 568 GW 573
            +
Sbjct: 346 SY 347

>GID1_ORYSA (Q6L545) Gibberellin receptor GID1 (EC 3.-.-.-)|
           (Gibberellin-insensitive dwarf protein 1) (Protein
           GIBBERELLIN INSENSITIVE DWARF1)
          Length = 354

 Score = 29.6 bits (65), Expect = 6.5
 Identities = 14/30 (46%), Positives = 16/30 (53%)
 Frame = -2

Query: 531 RDRSSMQPFGVQGRNSGFLPFIASLPMFKG 442
           RD  +  PFG  GR  G LPF  SL +  G
Sbjct: 265 RDHPACNPFGPNGRRLGGLPFAKSLIIVSG 294

>ISPH_SYNPX (Q7U9K4) 4-hydroxy-3-methylbut-2-enyl diphosphate reductase (EC|
           1.17.1.2)
          Length = 399

 Score = 29.6 bits (65), Expect = 6.5
 Identities = 26/86 (30%), Positives = 34/86 (39%), Gaps = 11/86 (12%)
 Frame = +2

Query: 176 LAVVIVGSRKDSQTYVQMKRKACAEVGIRSFDVDLPEDISEAALVAEVHRLN-------- 331
           L VVI G    + T++Q   +     GIRSF +D P+ +   A   E   LN        
Sbjct: 308 LMVVIGGFNSSNTTHLQ---EIALSRGIRSFHIDTPDRLDAQANAIEHKPLNENLRLESN 364

Query: 332 ---ADPAVHGILVQLPLPKHINEEII 400
              A P   GI      P    EE+I
Sbjct: 365 FLPAGPVTVGITSGASTPDRAVEEVI 390


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 61,710,625
Number of Sequences: 219361
Number of extensions: 1148406
Number of successful extensions: 3691
Number of sequences better than 10.0: 38
Number of HSP's better than 10.0 without gapping: 3602
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3662
length of database: 80,573,946
effective HSP length: 106
effective length of database: 57,321,680
effective search space used: 4929664480
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)