ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | bart39d10 |
|---|---|
| Clone Library Name | barley_pub |
>M2OM_HUMAN (Q02978) Mitochondrial 2-oxoglutarate/malate carrier protein (OGCP)| (Solute carrier family 25 member 11) Length = 313 Score = 153 bits (387), Expect = 3e-37 Identities = 89/164 (54%), Positives = 112/164 (68%), Gaps = 8/164 (4%) Frame = +2 Query: 131 KTIKPFVNGGASGMLATCVIQPIDMIKVKIQL-GEGSAAQVAKTMY-------ANEGLGS 286 K++K F+ GG +GM AT +QP+D++K ++QL GEG+ + KT + EGL Sbjct: 20 KSVK-FLFGGLAGMGATVFVQPLDLVKNRMQLSGEGAKTREYKTSFHALTSILKAEGLRG 78 Query: 287 FYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGS 466 Y GLSAGLLRQATYTT RLG + VL + A DG P + KA IG+TAGA GA VG+ Sbjct: 79 IYTGLSAGLLRQATYTTTRLGIYTVLFERLTGA-DGTPPGFLLKAVIGMTAGATGAFVGT 137 Query: 467 PADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 PA++ALIRM AD LPA QRR YKN F+AL RIT +EGVL LW+ Sbjct: 138 PAEVALIRMTADGRLPADQRRGYKNVFNALIRITREEGVLTLWR 181 Score = 33.1 bits (74), Expect = 0.63 Identities = 25/110 (22%), Positives = 46/110 (41%), Gaps = 1/110 (0%) Frame = +2 Query: 272 EGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIG-LTAGAI 448 EG+ + ++G + R A+L S+ +K + G + F + +G + Sbjct: 174 EGVLTLWRGCIPTMARAVVVNAAQLASYS--QSKQFLLDSGYFSDNILCHFCASMISGLV 231 Query: 449 GACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 P D+A R+Q + + YKN L+++ EG +LWK Sbjct: 232 TTAASMPVDIAKTRIQNMRMIDG--KPEYKNGLDVLFKVVRYEGFFSLWK 279
>M2OM_MOUSE (Q9CR62) Mitochondrial 2-oxoglutarate/malate carrier protein (OGCP)| (Solute carrier family 25 member 11) Length = 313 Score = 150 bits (378), Expect = 4e-36 Identities = 87/164 (53%), Positives = 110/164 (67%), Gaps = 8/164 (4%) Frame = +2 Query: 131 KTIKPFVNGGASGMLATCVIQPIDMIKVKIQL-GEGSAAQVAKTMY-------ANEGLGS 286 K++K F+ GG +GM AT +QP+D++K ++QL GEG+ + KT + EGL Sbjct: 20 KSVK-FLFGGLAGMGATVFVQPLDLVKNRMQLSGEGAKTREYKTSFHALTSILKTEGLKG 78 Query: 287 FYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGS 466 Y GLSAGLLRQATYTT RLG + VL + A DG P + KA IG+TAGA GA VG+ Sbjct: 79 IYTGLSAGLLRQATYTTTRLGIYTVLFERLTGA-DGTPPGFLLKALIGMTAGATGAFVGT 137 Query: 467 PADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 PA++ALIRM AD LPA QRR YKN F+AL RI +EGV LW+ Sbjct: 138 PAEVALIRMTADGRLPADQRRGYKNVFNALVRIAREEGVPTLWR 181 Score = 30.8 bits (68), Expect = 3.1 Identities = 24/110 (21%), Positives = 44/110 (40%), Gaps = 1/110 (0%) Frame = +2 Query: 272 EGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIG-LTAGAI 448 EG+ + ++G + R A+L S+ +K + G + F + +G + Sbjct: 174 EGVPTLWRGCIPTMARAVVVNAAQLASYS--QSKQFLLDSGYFSDNILCHFCASMISGLV 231 Query: 449 GACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 P D+ R+Q + + YKN L ++ EG +LWK Sbjct: 232 TTAASMPVDIVKTRIQNMRMIDG--KPEYKNGLDVLLKVVRYEGFFSLWK 279
>M2OM_BOVIN (P22292) Mitochondrial 2-oxoglutarate/malate carrier protein (OGCP)| (Solute carrier family 25 member 11) Length = 313 Score = 149 bits (375), Expect = 8e-36 Identities = 86/164 (52%), Positives = 110/164 (67%), Gaps = 8/164 (4%) Frame = +2 Query: 131 KTIKPFVNGGASGMLATCVIQPIDMIKVKIQL-GEGSAAQVAKTMY-------ANEGLGS 286 K++K F+ GG +GM AT +QP+D++K ++QL GEG+ + KT + EGL Sbjct: 20 KSVK-FLFGGLAGMGATVFVQPLDLVKNRMQLSGEGAKTREYKTSFHALISILRAEGLRG 78 Query: 287 FYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGS 466 Y GLSAGLLRQATYTT RLG + VL + A DG P + KA IG+TAGA GA VG+ Sbjct: 79 IYTGLSAGLLRQATYTTTRLGIYTVLFERLTGA-DGTPPGFLLKAVIGMTAGATGAFVGT 137 Query: 467 PADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 PA++ALIRM AD LP QRR YKN F+AL+RI +EGV LW+ Sbjct: 138 PAEVALIRMTADGRLPVDQRRGYKNVFNALFRIVQEEGVPTLWR 181 Score = 30.8 bits (68), Expect = 3.1 Identities = 24/110 (21%), Positives = 44/110 (40%), Gaps = 1/110 (0%) Frame = +2 Query: 272 EGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIG-LTAGAI 448 EG+ + ++G + R A+L S+ +K + G + F + +G + Sbjct: 174 EGVPTLWRGCIPTMARAVVVNAAQLASYS--QSKQFLLDSGYFSDNILCHFCASMISGLV 231 Query: 449 GACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 P D+ R+Q + + YKN L ++ EG +LWK Sbjct: 232 TTAASMPVDIVKTRIQNMRMIDG--KPEYKNGLDVLVKVVRYEGFFSLWK 279
>M2OM_RAT (P97700) Mitochondrial 2-oxoglutarate/malate carrier protein (OGCP)| (Solute carrier family 25 member 11) Length = 313 Score = 146 bits (368), Expect = 5e-35 Identities = 86/164 (52%), Positives = 108/164 (65%), Gaps = 8/164 (4%) Frame = +2 Query: 131 KTIKPFVNGGASGMLATCVIQPIDMIKVKIQL-GEGSAAQVAKTMY-------ANEGLGS 286 K++K F+ GG +GM AT +QP+D++ ++QL GEG+ + KT + EGL Sbjct: 20 KSVK-FLFGGLAGMGATVFVQPLDLVXNRMQLSGEGAKTREYKTSFHALTSILKAEGLRG 78 Query: 287 FYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGS 466 Y GLSAGLLRQATYTT RLG + VL + A DG P + KA IG+TAGA GA VG Sbjct: 79 IYTGLSAGLLRQATYTTTRLGIYTVLFERLTGA-DGTPPGFLLKALIGMTAGATGAFVGP 137 Query: 467 PADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 PA++ALIRM AD LPA QRR YKN F+AL RI +EGV LW+ Sbjct: 138 PAEVALIRMTADGRLPADQRRGYKNVFNALIRIAREEGVPTLWR 181 Score = 32.0 bits (71), Expect = 1.4 Identities = 23/109 (21%), Positives = 44/109 (40%) Frame = +2 Query: 272 EGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIG 451 EG+ + ++G + R A+L S+ +++ L I + +G + Sbjct: 174 EGVPTLWRGCIPTMARAVVVNAAQLASYSQSKQFLLDSGYFSDNILCHFCAI-MISGLVT 232 Query: 452 ACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 P D+ R+Q + ++ YKN L ++ EG +LWK Sbjct: 233 TAASMPVDIVKTRIQNMRMID--EKPEYKNGLDVLLKVVRYEGFFSLWK 279
>DIC1_YEAST (Q06143) Mitochondrial dicarboxylate transporter (Dicarboxylate| carrier 1) (DTP) Length = 298 Score = 106 bits (264), Expect = 6e-23 Identities = 65/159 (40%), Positives = 95/159 (59%), Gaps = 7/159 (4%) Frame = +2 Query: 131 KTIK-PFVNGGASGMLATCVIQPIDMIKVKIQ---LGEGSAAQVAKTMYANEGLGSFYKG 298 K IK P+ GGA+G+ AT V P+D+ KV++Q + + + ++ +++ ANEG+ Y G Sbjct: 11 KNIKYPWWYGGAAGIFATMVTHPLDLAKVRLQAAPMPKPTLFRMLESILANEGVVGLYSG 70 Query: 299 LSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFI---GLTAGAIGACVGSP 469 LSA +LRQ TYTT R G++ +L I L A++ + +GAIG G+ Sbjct: 71 LSAAVLRQCTYTTVRFGAYDLLKENVIPREQ-----LTNMAYLLPCSMFSGAIGGLAGNF 125 Query: 470 ADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVL 586 AD+ IRMQ DS L AA+RR+YKNA +Y+I EG L Sbjct: 126 ADVVNIRMQNDSALEAAKRRNYKNAIDGVYKIYRYEGGL 164 Score = 29.6 bits (65), Expect = 6.9 Identities = 22/76 (28%), Positives = 33/76 (43%), Gaps = 3/76 (3%) Frame = +2 Query: 164 SGMLATCVIQPIDMIKVKIQLGEGS---AAQVAKTMYANEGLGSFYKGLSAGLLRQATYT 334 +G++AT V P D++K +I G G A ++ EG ++G Sbjct: 217 AGLVATTVCSPADVMKTRIMNGSGDHQPALKILADAVRKEGPSFMFRGWLPSF------- 269 Query: 335 TARLGSFRVLTNKAIE 382 RLG F +L AIE Sbjct: 270 -TRLGPFTMLIFFAIE 284
>DIC_HUMAN (Q9UBX3) Mitochondrial dicarboxylate carrier (Solute carrier family| 25 member 10) Length = 287 Score = 102 bits (253), Expect = 1e-21 Identities = 56/154 (36%), Positives = 85/154 (55%), Gaps = 7/154 (4%) Frame = +2 Query: 155 GGASGMLATCVIQPIDMIKVKIQLGE-------GSAAQVAKTMYANEGLGSFYKGLSAGL 313 GG + A C P+D++KV +Q + G A +V +T +G+ + Y GLSA L Sbjct: 13 GGLASCGAACCTHPLDLLKVHLQTQQEVKLRMTGMALRVVRT----DGILALYSGLSASL 68 Query: 314 LRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLALIRM 493 RQ TY+ R + + ++ + + G PLP +K +G +G G VG+PADL +RM Sbjct: 69 CRQMTYSLTRFAIYETVRDRVAKGSQG-PLPFHEKVLLGSVSGLAGGFVGTPADLVNVRM 127 Query: 494 QADSTLPAAQRRHYKNAFHALYRITADEGVLALW 595 Q D LP QRR+Y +A LYR+ +EG+ L+ Sbjct: 128 QNDVKLPQGQRRNYAHALDGLYRVAREEGLRRLF 161
>DIC1_CANGA (Q6FTN2) Mitochondrial dicarboxylate transporter (Dicarboxylate| carrier 1) Length = 295 Score = 99.8 bits (247), Expect = 5e-21 Identities = 59/154 (38%), Positives = 88/154 (57%), Gaps = 3/154 (1%) Frame = +2 Query: 143 PFVNGGASGMLATCVIQPIDMIKVKIQ---LGEGSAAQVAKTMYANEGLGSFYKGLSAGL 313 P+ GGA+G+ A P+D+ KV++Q + + + Q+ +++ NEG+ Y GLSA L Sbjct: 9 PWWYGGAAGIFAVMNTHPLDLTKVRLQAAPIPKPTIVQMLRSILKNEGIVGLYAGLSASL 68 Query: 314 LRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLALIRM 493 LRQ TYTTAR G + L I + + + A + +GA+G G+ ADL IRM Sbjct: 69 LRQCTYTTARFGMYDALKEHVIPRDKLTNMWYLLGA--SMVSGALGGLAGNFADLINIRM 126 Query: 494 QADSTLPAAQRRHYKNAFHALYRITADEGVLALW 595 Q DS LP +RR+YKNA + +I EG +L+ Sbjct: 127 QNDSALPLDKRRNYKNAIDGMVKIYKAEGAKSLF 160
>DIC_MOUSE (Q9QZD8) Mitochondrial dicarboxylate carrier (Solute carrier family| 25 member 10) Length = 287 Score = 98.2 bits (243), Expect = 2e-20 Identities = 56/154 (36%), Positives = 82/154 (53%), Gaps = 7/154 (4%) Frame = +2 Query: 155 GGASGMLATCVIQPIDMIKVKIQLGE-------GSAAQVAKTMYANEGLGSFYKGLSAGL 313 GG + A C P+D++KV +Q + G A QV +T +G + Y GLSA L Sbjct: 12 GGLASCGAACCTHPLDLLKVHLQTQQEVKLRMTGMALQVVRT----DGFLALYNGLSASL 67 Query: 314 LRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLALIRM 493 RQ TY+ R + + + + + G PLP K +G +G G VG+PADL +RM Sbjct: 68 CRQMTYSLTRFAIYETMRDYMTKDSQG-PLPFYNKVLLGGISGLTGGFVGTPADLVNVRM 126 Query: 494 QADSTLPAAQRRHYKNAFHALYRITADEGVLALW 595 Q D LP +QRR+Y +A LYR+ +E + L+ Sbjct: 127 QNDMKLPPSQRRNYSHALDGLYRVAREESLRKLF 160
>UCP1_RAT (P04633) Mitochondrial brown fat uncoupling protein 1 (UCP 1)| (Thermogenin) Length = 306 Score = 75.1 bits (183), Expect = 1e-13 Identities = 48/159 (30%), Positives = 75/159 (47%), Gaps = 10/159 (6%) Frame = +2 Query: 152 NGGASGMLATCVIQPIDMIKVKIQL-GEGSAAQVAK---------TMYANEGLGSFYKGL 301 + G S LA + P+D KV++Q+ GEG A+ + T+ EGL Y GL Sbjct: 18 SAGVSACLADIITFPLDTAKVRLQIQGEGQASSTIRYKGVLGTITTLAKTEGLPKLYSGL 77 Query: 302 SAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLA 481 AG+ RQ ++ + R+G + + + + P L K GL G + +G P ++ Sbjct: 78 PAGIQRQISFASLRIGLYDTV-QEYFSSGRETPASLGSKISAGLMTGGVAVFIGQPTEVV 136 Query: 482 LIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 +RMQA S L + R Y ++A I E + LWK Sbjct: 137 KVRMQAQSHLHGIKPR-YTGTYNAYRVIATTESLSTLWK 174 Score = 35.0 bits (79), Expect = 0.17 Identities = 21/78 (26%), Positives = 36/78 (46%), Gaps = 4/78 (5%) Frame = +2 Query: 164 SGMLATCVIQPIDMIKVK-IQLGEG---SAAQVAKTMYANEGLGSFYKGLSAGLLRQATY 331 +G T + P+D++K + I G S A TMY EG +F+KG + LR ++ Sbjct: 221 AGFCTTLLASPVDVVKTRFINSLPGQYPSVPSCAMTMYTKEGPAAFFKGFAPSFLRLGSW 280 Query: 332 TTARLGSFRVLTNKAIEA 385 F L + +++ Sbjct: 281 NVIMFVCFEQLKKELMKS 298
>UCP1_MOUSE (P12242) Mitochondrial brown fat uncoupling protein 1 (UCP 1)| (Thermogenin) Length = 306 Score = 74.3 bits (181), Expect = 2e-13 Identities = 48/159 (30%), Positives = 75/159 (47%), Gaps = 10/159 (6%) Frame = +2 Query: 152 NGGASGMLATCVIQPIDMIKVKIQL-GEGSAAQVAK---------TMYANEGLGSFYKGL 301 + G S LA + P+D KV++Q+ GEG A+ + T+ EGL Y GL Sbjct: 18 SAGVSACLADIITFPLDTAKVRLQIQGEGQASSTIRYKGVLGTITTLAKTEGLPKLYSGL 77 Query: 302 SAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLA 481 AG+ RQ ++ + R+G + + + + P L K GL G + +G P ++ Sbjct: 78 PAGIQRQISFASLRIGLYDSV-QEYFSSGRETPASLGNKISAGLMTGGVAVFIGQPTEVV 136 Query: 482 LIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 +RMQA S L + R Y ++A I E + LWK Sbjct: 137 KVRMQAQSHLHGIKPR-YTGTYNAYRVIATTESLSTLWK 174 Score = 33.5 bits (75), Expect = 0.48 Identities = 21/78 (26%), Positives = 36/78 (46%), Gaps = 4/78 (5%) Frame = +2 Query: 164 SGMLATCVIQPIDMIKVK-IQLGEG---SAAQVAKTMYANEGLGSFYKGLSAGLLRQATY 331 +G T + P+D++K + I G S A +MY EG +F+KG A LR ++ Sbjct: 221 AGFCTTLLASPVDVVKTRFINSLPGQYPSVPSCAMSMYTKEGPTAFFKGFVASFLRLGSW 280 Query: 332 TTARLGSFRVLTNKAIEA 385 F L + +++ Sbjct: 281 NVIMFVCFEQLKKELMKS 298
>UCP3_HUMAN (P55916) Mitochondrial uncoupling protein 3 (UCP 3)| Length = 312 Score = 73.6 bits (179), Expect = 4e-13 Identities = 54/169 (31%), Positives = 75/169 (44%), Gaps = 18/169 (10%) Frame = +2 Query: 146 FVNGGASGMLATCVIQPIDMIKVKIQL-GEGSAAQVAK------------TMYANEGLGS 286 F+ G + A V P+D KV++Q+ GE A Q A+ TM EG S Sbjct: 17 FLGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRGVLGTILTMVRTEGPCS 76 Query: 287 FYKGLSAGLLRQATYTTARLGSF----RVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGA 454 Y GL AGL RQ ++ + R+G + +V T K + + L + G T GA+ Sbjct: 77 PYNGLVAGLQRQMSFASIRIGLYDSVKQVYTPKGADNSS-----LTTRILAGCTTGAMAV 131 Query: 455 CVGSPADLALIRMQADSTL-PAAQRRHYKNAFHALYRITADEGVLALWK 598 P D+ +R QA L P+ R Y A I +EGV LWK Sbjct: 132 TCAQPTDVVKVRFQASIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLWK 180 Score = 40.4 bits (93), Expect = 0.004 Identities = 39/162 (24%), Positives = 64/162 (39%), Gaps = 14/162 (8%) Frame = +2 Query: 155 GGASGMLATCVIQPIDMIKVKIQ----LGEGSAAQ-------VAKTMYANEGLGSFYKGL 301 G +G +A QP D++KV+ Q LG + + +T+ EG+ +KG Sbjct: 123 GCTTGAMAVTCAQPTDVVKVRFQASIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLWKGT 182 Query: 302 SAGLLRQATYTTARLGSFRVLTNKAIE---ANDGRPLPLVQKAFIGLTAGAIGACVGSPA 472 ++R A A + ++ +L K ++ D P V AG V SP Sbjct: 183 LPNIMRNAIVNCAEVVTYDILKEKLLDYHLLTDNFPCHFVS----AFGAGFCATVVASPV 238 Query: 473 DLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 D+ R P Q Y + + ++ A EG A +K Sbjct: 239 DVVKTRYM---NSPPGQ---YFSPLDCMIKMVAQEGPTAFYK 274
>UCP3_CANFA (Q9N2I9) Mitochondrial uncoupling protein 3 (UCP 3)| Length = 311 Score = 73.6 bits (179), Expect = 4e-13 Identities = 52/172 (30%), Positives = 74/172 (43%), Gaps = 17/172 (9%) Frame = +2 Query: 134 TIKPFVNGGASGMLATCVIQPIDMIKVKIQL-GEGSAAQVAK------------TMYANE 274 T F+ G + A + P+D KV++Q+ GE A Q A+ TM E Sbjct: 13 TAVKFLGAGTAACFADLLTFPLDTAKVRLQIQGENQATQAARRIQYRGVLGTILTMVRTE 72 Query: 275 GLGSFYKGLSAGLLRQATYTTARLGSF----RVLTNKAIEANDGRPLPLVQKAFIGLTAG 442 G S Y GL AGL RQ ++ + R+G + + T K + + + + G T G Sbjct: 73 GPRSPYNGLVAGLQRQMSFASIRIGLYDSVKQFYTPKGSDHSS-----ITTRILAGCTTG 127 Query: 443 AIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 A+ P D+ +R QA L A R Y A I +EGV LWK Sbjct: 128 AMAVSCAQPTDVVKVRFQASIHLGAGSNRKYSGTMDAYRTIAREEGVRGLWK 179 Score = 44.7 bits (104), Expect = 2e-04 Identities = 41/161 (25%), Positives = 65/161 (40%), Gaps = 13/161 (8%) Frame = +2 Query: 155 GGASGMLATCVIQPIDMIKVKIQ----LGEGSAAQVAKTMYA------NEGLGSFYKGLS 304 G +G +A QP D++KV+ Q LG GS + + TM A EG+ +KG Sbjct: 123 GCTTGAMAVSCAQPTDVVKVRFQASIHLGAGSNRKYSGTMDAYRTIAREEGVRGLWKGTL 182 Query: 305 AGLLRQATYTTARLGSFRVLTNKAIE---ANDGRPLPLVQKAFIGLTAGAIGACVGSPAD 475 + R A A + ++ ++ K ++ D P L+ AG V SP D Sbjct: 183 PNITRNAIVNCAEMVTYDIIKEKLLDYHLLTDNFPCHLIS----AFGAGFCATVVASPVD 238 Query: 476 LALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 + R P Q Y + + ++ EG A +K Sbjct: 239 VVKTRYM---NSPPGQ---YCSPLDCMLKMVTQEGPTAFYK 273
>UCP1_PHOSU (Q9ER18) Mitochondrial brown fat uncoupling protein 1 (UCP 1)| (Thermogenin) Length = 307 Score = 72.4 bits (176), Expect = 9e-13 Identities = 45/159 (28%), Positives = 75/159 (47%), Gaps = 10/159 (6%) Frame = +2 Query: 152 NGGASGMLATCVIQPIDMIKVKIQL-GEGSAAQVAK---------TMYANEGLGSFYKGL 301 + G + LA + P+D KV++Q+ GEG + + T+ EGL Y GL Sbjct: 19 SAGVAACLADIITFPLDTAKVRLQIQGEGQTSSTIRYKGVLGTITTLAKTEGLPKLYSGL 78 Query: 302 SAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLA 481 AG+ RQ ++ + R+G + + + + P LV + GL G + +G P ++ Sbjct: 79 PAGIQRQISFASLRIGLYDTV-QEYFSSGKETPPTLVNRISAGLMTGGVAVFIGQPTEVV 137 Query: 482 LIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 +R+QA S L + R Y ++A I E + LWK Sbjct: 138 KVRLQAQSHLHGIKPR-YTGTYNAYRIIATTESLSTLWK 175 Score = 31.2 bits (69), Expect = 2.4 Identities = 21/78 (26%), Positives = 35/78 (44%), Gaps = 4/78 (5%) Frame = +2 Query: 164 SGMLATCVIQPIDMIKVK-IQLGEG---SAAQVAKTMYANEGLGSFYKGLSAGLLRQATY 331 +G T + P D++K + I G S A TM+ EG +F+KG LR A++ Sbjct: 222 AGFCTTFLASPADVVKTRFINSLPGQYPSVPSCAMTMFTKEGPTAFFKGFVPSFLRLASW 281 Query: 332 TTARLGSFRVLTNKAIEA 385 F L + +++ Sbjct: 282 NVIMFVCFEQLKKELMKS 299
>OAC1_YEAST (P32332) Mitochondrial oxaloacetate transport protein| (Mitochondrial carrier protein PMT) Length = 324 Score = 71.2 bits (173), Expect = 2e-12 Identities = 58/188 (30%), Positives = 91/188 (48%), Gaps = 18/188 (9%) Frame = +2 Query: 89 DAKQQQAAAPTGVWKTIK--PFVNGGASGMLATCVIQPIDMIKVKIQL-GE--GSAAQVA 253 ++KQ + T K K FV GG + +A V PI++IK+++QL GE SAA+V Sbjct: 5 NSKQDKQIEKTAAQKISKFGSFVAGGLAACIAVTVTNPIELIKIRMQLQGEMSASAAKVY 64 Query: 254 K-------TMYANEGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEA--NDGRPLP 406 K ++ NEG+ KGL+A + Q +RLG + + + + D P Sbjct: 65 KNPIQGMAVIFKNEGIKGLQKGLNAAYIYQIGLNGSRLGFYEPIRSSLNQLFFPDQEPHK 124 Query: 407 LVQ---KAFIGLTAGAIGACVGSPADLALIRMQADST-LPAAQRRHYKNAFHALYRITAD 574 + F G +G IGA +GSP L R+Q+ S + ++ HY ++ L I Sbjct: 125 VQSVGVNVFSGAASGIIGAVIGSPLFLVKTRLQSYSEFIKIGEQTHYTGVWNGLVTIFKT 184 Query: 575 EGVLALWK 598 EGV L++ Sbjct: 185 EGVKGLFR 192
>UCP2_PIG (O97562) Mitochondrial uncoupling protein 2 (UCP 2)| Length = 309 Score = 70.9 bits (172), Expect = 3e-12 Identities = 51/169 (30%), Positives = 77/169 (45%), Gaps = 14/169 (8%) Frame = +2 Query: 134 TIKPFVNGGASGMLATCVIQPIDMIKVKIQL-----GEGSAAQVAK---------TMYAN 271 T+K F+ G + +A + P+D KV++Q+ G AA A+ TM N Sbjct: 14 TVK-FLGAGTAACIADLITFPLDTAKVRLQIQGERRGPVQAAASAQYRGVLGTILTMVRN 72 Query: 272 EGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIG 451 EG S Y GL AGL RQ ++ + R+G + + K + + G T GA+ Sbjct: 73 EGPRSLYNGLVAGLQRQMSFASVRIGLYDSV--KHFYTKGSEHAGIGSRLLAGSTTGALA 130 Query: 452 ACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 V P D+ +R QA + A R Y++ A I +EG+ LWK Sbjct: 131 VAVAQPTDVVKVRFQAQAR--AGGGRRYRSTVDAYKTIAREEGLRGLWK 177 Score = 47.4 bits (111), Expect = 3e-05 Identities = 43/159 (27%), Positives = 65/159 (40%), Gaps = 11/159 (6%) Frame = +2 Query: 155 GGASGMLATCVIQPIDMIKVKIQL----GEG----SAAQVAKTMYANEGLGSFYKGLSAG 310 G +G LA V QP D++KV+ Q G G S KT+ EGL +KG S Sbjct: 123 GSTTGALAVAVAQPTDVVKVRFQAQARAGGGRRYRSTVDAYKTIAREEGLRGLWKGTSPN 182 Query: 311 LLRQATYTTARLGSFRVLTNKAIEAN---DGRPLPLVQKAFIGLTAGAIGACVGSPADLA 481 + R A A L ++ ++ + ++A+ D P AG + SP D+ Sbjct: 183 VARNAIVNCAELVTYDLIKDTLLKADLMTDDLPCHFTS----AFGAGFCTTVIASPVDVV 238 Query: 482 LIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 R ++ P Y +A H + EG A +K Sbjct: 239 KTRYM--NSAPG----QYSSAGHCALTMLQKEGPRAFYK 271
>UCP3_BOVIN (O77792) Mitochondrial uncoupling protein 3 (UCP 3)| Length = 311 Score = 70.1 bits (170), Expect = 5e-12 Identities = 50/168 (29%), Positives = 72/168 (42%), Gaps = 17/168 (10%) Frame = +2 Query: 146 FVNGGASGMLATCVIQPIDMIKVKIQL-GEGSAAQVAK------------TMYANEGLGS 286 F+ G + A + P+D KV++Q+ GE AA A+ TM EG S Sbjct: 17 FLAAGTAACFADLLTFPLDTAKVRLQIQGENQAALAARSAQYRGVLGTILTMVRTEGPRS 76 Query: 287 FYKGLSAGLLRQATYTTARLGSF----RVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGA 454 Y GL AGL RQ ++ + R+G + + T K + + ++ + G T GA+ Sbjct: 77 LYSGLVAGLQRQMSFASIRIGLYDSVKQFYTPKGSDHSS-----IITRILAGCTTGAMAV 131 Query: 455 CVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 P D+ IR QA R Y A I +EGV LWK Sbjct: 132 TCAQPTDVVKIRFQASMHTGLGGNRKYSGTMDAYRTIAREEGVRGLWK 179 Score = 41.6 bits (96), Expect = 0.002 Identities = 38/161 (23%), Positives = 63/161 (39%), Gaps = 13/161 (8%) Frame = +2 Query: 155 GGASGMLATCVIQPIDMIKVKIQL----GEGSAAQVAKTMYA------NEGLGSFYKGLS 304 G +G +A QP D++K++ Q G G + + TM A EG+ +KG+ Sbjct: 123 GCTTGAMAVTCAQPTDVVKIRFQASMHTGLGGNRKYSGTMDAYRTIAREEGVRGLWKGIL 182 Query: 305 AGLLRQATYTTARLGSFRVLTNKAIE---ANDGRPLPLVQKAFIGLTAGAIGACVGSPAD 475 + R A + ++ ++ K ++ D P V AG V SP D Sbjct: 183 PNITRNAIVNCGEMVTYDIIKEKLLDYHLLTDNFPCHFVS----AFGAGFCATLVASPVD 238 Query: 476 LALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 + R P Q Y + F + ++ EG A +K Sbjct: 239 VVKTRYM---NSPPGQ---YHSPFDCMLKMVTQEGPTAFYK 273
>UCP3_PIG (O97649) Mitochondrial uncoupling protein 3 (UCP 3)| Length = 308 Score = 70.1 bits (170), Expect = 5e-12 Identities = 50/169 (29%), Positives = 74/169 (43%), Gaps = 14/169 (8%) Frame = +2 Query: 134 TIKPFVNGGASGMLATCVIQPIDMIKVKIQL-GEGSAAQVAK---------TMYANEGLG 283 T + G + A + P+D KV++Q+ GE AA+ A+ TM NEG Sbjct: 13 TAVKLLGAGTAACFADLLTFPLDTAKVRLQIQGENQAARSAQYRGVLGTILTMVRNEGPR 72 Query: 284 SFYKGLSAGLLRQATYTTARLGSF----RVLTNKAIEANDGRPLPLVQKAFIGLTAGAIG 451 S Y GL AGL RQ ++ + R+G + ++ T K + + + + G T GA+ Sbjct: 73 SPYNGLVAGLQRQMSFASIRIGLYDSVKQLYTPKGSDHSS-----ITTRILAGCTTGAMA 127 Query: 452 ACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 P D+ +R QA R Y A I +EGV LWK Sbjct: 128 VTCAQPTDVVKVRFQASIHAGPRSNRKYSGTMDAYRTIAREEGVRGLWK 176 Score = 44.3 bits (103), Expect = 3e-04 Identities = 41/161 (25%), Positives = 64/161 (39%), Gaps = 13/161 (8%) Frame = +2 Query: 155 GGASGMLATCVIQPIDMIKVKIQL----GEGSAAQVAKTMYA------NEGLGSFYKGLS 304 G +G +A QP D++KV+ Q G S + + TM A EG+ +KG+ Sbjct: 120 GCTTGAMAVTCAQPTDVVKVRFQASIHAGPRSNRKYSGTMDAYRTIAREEGVRGLWKGIL 179 Query: 305 AGLLRQATYTTARLGSFRVLTNKAIE---ANDGRPLPLVQKAFIGLTAGAIGACVGSPAD 475 + R A A + ++ V+ K ++ D P V AG V SP D Sbjct: 180 PNITRNAIVNCAEMVTYDVIKEKVLDYHLLTDNLPCHFVS----AFGAGFCATVVASPVD 235 Query: 476 LALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 + R P Q Y+N + ++ EG A +K Sbjct: 236 VVKTRYM---NSPPGQ---YQNPLDCMLKMVTQEGPTAFYK 270
>UCP3_MOUSE (P56501) Mitochondrial uncoupling protein 3 (UCP 3)| Length = 308 Score = 69.7 bits (169), Expect = 6e-12 Identities = 50/169 (29%), Positives = 74/169 (43%), Gaps = 14/169 (8%) Frame = +2 Query: 134 TIKPFVNGGASGMLATCVIQPIDMIKVKIQL-GEGSAAQVAK---------TMYANEGLG 283 T+ F+ G + A + P+D KV++Q+ GE AQ + TM EG Sbjct: 13 TVVKFLGAGTAACFADLLTFPLDTAKVRLQIQGENPGAQSVQYRGVLGTILTMVRTEGPR 72 Query: 284 SFYKGLSAGLLRQATYTTARLGSF----RVLTNKAIEANDGRPLPLVQKAFIGLTAGAIG 451 S Y GL AGL RQ ++ + R+G + + T K + + + + G T GA+ Sbjct: 73 SPYSGLVAGLHRQMSFASIRIGLYDSVKQFYTPKGADHSS-----VAIRILAGCTTGAMA 127 Query: 452 ACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 P D+ +R QA L R Y+ A I +EGV LWK Sbjct: 128 VTCAQPTDVVKVRFQAMIRLGTGGERKYRGTMDAYRTIAREEGVRGLWK 176 Score = 50.1 bits (118), Expect = 5e-06 Identities = 42/161 (26%), Positives = 66/161 (40%), Gaps = 13/161 (8%) Frame = +2 Query: 155 GGASGMLATCVIQPIDMIKVKIQ----LGEGSAAQVAKTMYA------NEGLGSFYKGLS 304 G +G +A QP D++KV+ Q LG G + TM A EG+ +KG Sbjct: 120 GCTTGAMAVTCAQPTDVVKVRFQAMIRLGTGGERKYRGTMDAYRTIAREEGVRGLWKGTW 179 Query: 305 AGLLRQATYTTARLGSFRVLTNKAIEAN---DGRPLPLVQKAFIGLTAGAIGACVGSPAD 475 + R A A + ++ ++ K +E++ D P V AG V SP D Sbjct: 180 PNITRNAIVNCAEMVTYDIIKEKLLESHLFTDNFPCHFVS----AFGAGFCATVVASPVD 235 Query: 476 LALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 + R A Y++ H + ++ A EG A +K Sbjct: 236 VVKTRYM------NAPLGRYRSPLHCMLKMVAQEGPTAFYK 270
>UCP2_RAT (P56500) Mitochondrial uncoupling protein 2 (UCP 2)| Length = 309 Score = 69.7 bits (169), Expect = 6e-12 Identities = 49/169 (28%), Positives = 75/169 (44%), Gaps = 14/169 (8%) Frame = +2 Query: 134 TIKPFVNGGASGMLATCVIQPIDMIKVKIQL---GEGSAAQVAK-----------TMYAN 271 T+K F+ G + +A + P+D KV++Q+ +G A A TM Sbjct: 14 TVK-FLGAGTAACIADLITFPLDTAKVRLQIQGESQGLARTAASAQYRGVLGTILTMVRT 72 Query: 272 EGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIG 451 EG S Y GL AGL RQ ++ + R+G + + K + + G T GA+ Sbjct: 73 EGPRSLYNGLVAGLQRQMSFASVRIGLYDSV--KQFYTKGSEHAGIGSRLLAGSTTGALA 130 Query: 452 ACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 V P D+ +R QA + A R Y++ A I +EG+ LWK Sbjct: 131 VAVAQPTDVVKVRFQAQAR--AGGGRRYQSTVEAYKTIAREEGIRGLWK 177 Score = 47.0 bits (110), Expect = 4e-05 Identities = 41/159 (25%), Positives = 63/159 (39%), Gaps = 11/159 (6%) Frame = +2 Query: 155 GGASGMLATCVIQPIDMIKVKIQL----GEG----SAAQVAKTMYANEGLGSFYKGLSAG 310 G +G LA V QP D++KV+ Q G G S + KT+ EG+ +KG S Sbjct: 123 GSTTGALAVAVAQPTDVVKVRFQAQARAGGGRRYQSTVEAYKTIAREEGIRGLWKGTSPN 182 Query: 311 LLRQATYTTARLGSFRVLTNKAIEAN---DGRPLPLVQKAFIGLTAGAIGACVGSPADLA 481 + R A L ++ ++ + ++AN D P AG + SP D+ Sbjct: 183 VARNAIVNCTELVTYDLIKDTLLKANLMTDDLPCHFTS----AFGAGFCTTVIASPVDVV 238 Query: 482 LIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 R + Y +A H + EG A +K Sbjct: 239 KTRYMNSAL------GQYHSAGHCALTMLRKEGPRAFYK 271
>UCP1_MESAU (P04575) Mitochondrial brown fat uncoupling protein 1 (UCP 1)| (Thermogenin) Length = 306 Score = 68.6 bits (166), Expect = 1e-11 Identities = 44/159 (27%), Positives = 73/159 (45%), Gaps = 10/159 (6%) Frame = +2 Query: 152 NGGASGMLATCVIQPIDMIKVKIQL-GEGSAAQVAK---------TMYANEGLGSFYKGL 301 + G + LA + P+D KV++Q+ GEG + + T+ EGL Y GL Sbjct: 18 SAGVAACLADIITFPLDTAKVRLQIQGEGQISSTIRYKGVLGTITTLAKTEGLPKLYSGL 77 Query: 302 SAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLA 481 AG+ RQ ++ + R+G + + + + P L + GL G + +G P ++ Sbjct: 78 PAGIQRQISFASLRIGLYDTV-QEYFSSGKETPPTLGNRISAGLMTGGVAVFIGQPTEVV 136 Query: 482 LIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 +R+QA S L + R Y ++A I E LWK Sbjct: 137 KVRLQAQSHLHGIKPR-YTGTYNAYRIIATTESFSTLWK 174
>UCP3_RAT (P56499) Mitochondrial uncoupling protein 3 (UCP 3)| Length = 308 Score = 68.2 bits (165), Expect = 2e-11 Identities = 49/169 (28%), Positives = 73/169 (43%), Gaps = 14/169 (8%) Frame = +2 Query: 134 TIKPFVNGGASGMLATCVIQPIDMIKVKIQL-GEGSAAQVAK---------TMYANEGLG 283 T+ F+ G + A + P+D KV++Q+ GE Q + TM EG Sbjct: 13 TVVKFLGAGTAACFADLLTFPLDTAKVRLQIQGENPGVQSVQYRGVLGTILTMVRTEGPR 72 Query: 284 SFYKGLSAGLLRQATYTTARLGSF----RVLTNKAIEANDGRPLPLVQKAFIGLTAGAIG 451 S Y GL AGL RQ ++ + R+G + + T K + + + + G T GA+ Sbjct: 73 SPYSGLVAGLHRQMSFASIRIGLYDSVKQFYTPKGTDHSS-----VAIRILAGCTTGAMA 127 Query: 452 ACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 P D+ +R QA L R Y+ A I +EGV LWK Sbjct: 128 VTCAQPTDVVKVRFQAMIRLGTGGERKYRGTMDAYRTIAREEGVRGLWK 176 Score = 50.1 bits (118), Expect = 5e-06 Identities = 42/161 (26%), Positives = 66/161 (40%), Gaps = 13/161 (8%) Frame = +2 Query: 155 GGASGMLATCVIQPIDMIKVKIQ----LGEGSAAQVAKTMYA------NEGLGSFYKGLS 304 G +G +A QP D++KV+ Q LG G + TM A EG+ +KG Sbjct: 120 GCTTGAMAVTCAQPTDVVKVRFQAMIRLGTGGERKYRGTMDAYRTIAREEGVRGLWKGTW 179 Query: 305 AGLLRQATYTTARLGSFRVLTNKAIEAN---DGRPLPLVQKAFIGLTAGAIGACVGSPAD 475 + R A A + ++ ++ K ++++ D P V AG V SP D Sbjct: 180 PNITRNAIVNCAEMVTYDIIKEKLLDSHLFTDNFPCHFVS----AFGAGFCATVVASPVD 235 Query: 476 LALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 + R A Y++ H + R+ A EG A +K Sbjct: 236 VVKTRYM------NAPPGRYRSPLHCMLRMVAQEGPTAFYK 270
>UCP2_MOUSE (P70406) Mitochondrial uncoupling protein 2 (UCP 2) (UCPH)| Length = 309 Score = 68.2 bits (165), Expect = 2e-11 Identities = 48/169 (28%), Positives = 73/169 (43%), Gaps = 14/169 (8%) Frame = +2 Query: 134 TIKPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAK--------------TMYAN 271 T+K F+ G + +A + P+D KV++Q+ S V TM Sbjct: 14 TVK-FLGAGTAACIADLITFPLDTAKVRLQIQGESQGLVRTAASAQYRGVLGTILTMVRT 72 Query: 272 EGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIG 451 EG S Y GL AGL RQ ++ + R+G + + K + + G T GA+ Sbjct: 73 EGPRSLYNGLVAGLQRQMSFASVRIGLYDSV--KQFYTKGSEHAGIGSRLLAGSTTGALA 130 Query: 452 ACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 V P D+ +R QA + A R Y++ A I +EG+ LWK Sbjct: 131 VAVAQPTDVVKVRFQAQAR--AGGGRRYQSTVEAYKTIAREEGIRGLWK 177 Score = 48.5 bits (114), Expect = 1e-05 Identities = 42/159 (26%), Positives = 64/159 (40%), Gaps = 11/159 (6%) Frame = +2 Query: 155 GGASGMLATCVIQPIDMIKVKIQL----GEG----SAAQVAKTMYANEGLGSFYKGLSAG 310 G +G LA V QP D++KV+ Q G G S + KT+ EG+ +KG S Sbjct: 123 GSTTGALAVAVAQPTDVVKVRFQAQARAGGGRRYQSTVEAYKTIAREEGIRGLWKGTSPN 182 Query: 311 LLRQATYTTARLGSFRVLTNKAIEAN---DGRPLPLVQKAFIGLTAGAIGACVGSPADLA 481 + R A A L ++ ++ + ++AN D P AG + SP D+ Sbjct: 183 VARNAIVNCAELVTYDLIKDTLLKANLMTDDLPCHFTS----AFGAGFCTTVIASPVDVV 238 Query: 482 LIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 R + Y +A H + EG A +K Sbjct: 239 KTRYMNSAL------GQYHSAGHCALTMLRKEGPRAFYK 271
>UCP2_CANFA (Q9N2J1) Mitochondrial uncoupling protein 2 (UCP 2)| Length = 309 Score = 68.2 bits (165), Expect = 2e-11 Identities = 50/169 (29%), Positives = 75/169 (44%), Gaps = 14/169 (8%) Frame = +2 Query: 134 TIKPFVNGGASGMLATCVIQPIDMIKVKIQL-----GEGSAAQVAK---------TMYAN 271 T+K F+ G + +A + P+D KV++Q+ G AA A+ TM Sbjct: 14 TVK-FLGAGTAACIADLITFPLDTAKVRLQIQGERQGPVRAAASAQYRGVLCTILTMVRT 72 Query: 272 EGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIG 451 EG S Y GL AGL RQ ++ + R+G + + K + + G T GA+ Sbjct: 73 EGPRSLYSGLVAGLQRQMSFASVRIGLYDSV--KQFYTKGSEHAGIGSRLLAGSTTGALA 130 Query: 452 ACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 V P D+ +R QA + A R Y++ A I +EG LWK Sbjct: 131 VAVAQPTDVVKVRFQAQAR--AGSGRRYQSTVDAYKTIAREEGFRGLWK 177
>UCP1_DICGR (Q8K404) Mitochondrial brown fat uncoupling protein 1 (UCP 1)| (Thermogenin) Length = 307 Score = 67.8 bits (164), Expect = 2e-11 Identities = 46/164 (28%), Positives = 75/164 (45%), Gaps = 10/164 (6%) Frame = +2 Query: 137 IKPFVNGGASGMLATCVIQPIDMIKVKIQL-GEGSAAQVAK---------TMYANEGLGS 286 +K F + G S LA + P+D KV++Q+ GEG + + T+ EG Sbjct: 15 VKTF-SAGISACLADIITFPLDTAKVRLQIQGEGQTSSTIRYKGVLGTITTLAKTEGWPK 73 Query: 287 FYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGS 466 Y GL AG+ RQ ++ + R+G + + + + P L + GL G + +G Sbjct: 74 LYSGLPAGIQRQISFASLRIGLYDTV-QEYFSSGKETPPTLGNRISAGLMTGGVAVFIGQ 132 Query: 467 PADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 P ++ +R+QA S L + R Y ++A I E LWK Sbjct: 133 PTEVVKVRLQAQSHLHGIKPR-YTGTYNAYRIIATTESFSTLWK 175
>UCP2_HUMAN (P55851) Mitochondrial uncoupling protein 2 (UCP 2) (UCPH)| Length = 309 Score = 67.8 bits (164), Expect = 2e-11 Identities = 48/169 (28%), Positives = 73/169 (43%), Gaps = 14/169 (8%) Frame = +2 Query: 134 TIKPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAKT--------------MYAN 271 T+K F+ G + +A + P+D KV++Q+ S V T M Sbjct: 14 TVK-FLGAGTAACIADLITFPLDTAKVRLQIQGESQGPVRATASAQYRGVMGTILTMVRT 72 Query: 272 EGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIG 451 EG S Y GL AGL RQ ++ + R+G + + K + + G T GA+ Sbjct: 73 EGPRSLYNGLVAGLQRQMSFASVRIGLYDSV--KQFYTKGSEHASIGSRLLAGSTTGALA 130 Query: 452 ACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 V P D+ +R QA + A R Y++ +A I +EG LWK Sbjct: 131 VAVAQPTDVVKVRFQAQAR--AGGGRRYQSTVNAYKTIAREEGFRGLWK 177
>UCP1_HUMAN (P25874) Mitochondrial brown fat uncoupling protein 1 (UCP 1)| (Thermogenin) Length = 307 Score = 67.4 bits (163), Expect = 3e-11 Identities = 46/159 (28%), Positives = 72/159 (45%), Gaps = 10/159 (6%) Frame = +2 Query: 152 NGGASGMLATCVIQPIDMIKVKIQL-GEGSAAQVAK---------TMYANEGLGSFYKGL 301 + G + LA + P+D KV++Q+ GE + V + + EG Y GL Sbjct: 19 SAGIAACLADVITFPLDTAKVRLQVQGECPTSSVIRYKGVLGTITAVVKTEGRMKLYSGL 78 Query: 302 SAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLA 481 AGL RQ + + R+G + + + P L K GLT G + +G P ++ Sbjct: 79 PAGLQRQISSASLRIGLYDTVQEFLTAGKETAP-SLGSKILAGLTTGGVAVFIGQPTEVV 137 Query: 482 LIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 +R+QA S L + R Y ++A I EG+ LWK Sbjct: 138 KVRLQAQSHLHGIKPR-YTGTYNAYRIIATTEGLTGLWK 175 Score = 38.1 bits (87), Expect = 0.020 Identities = 43/194 (22%), Positives = 77/194 (39%), Gaps = 30/194 (15%) Frame = +2 Query: 107 AAAPTGVWKTIKPFVNGG---------------ASGMLATCVIQPIDMIKVKIQL----- 226 A+ G++ T++ F+ G +G +A + QP +++KV++Q Sbjct: 89 ASLRIGLYDTVQEFLTAGKETAPSLGSKILAGLTTGGVAVFIGQPTEVVKVRLQAQSHLH 148 Query: 227 -------GEGSAAQVAKTMYANEGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEA 385 G +A ++ T EGL +KG + L+R L ++ ++ ++ Sbjct: 149 GIKPRYTGTYNAYRIIAT---TEGLTGLWKGTTPNLMRSVIINCTELVTYDLMKEAFVKN 205 Query: 386 N---DGRPLPLVQKAFIGLTAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHAL 556 N D P LV L AG + SP D+ R P Q YK+ + Sbjct: 206 NILADDVPCHLVS----ALIAGFCATAMSSPVDVVKTRF---INSPPGQ---YKSVPNCA 255 Query: 557 YRITADEGVLALWK 598 ++ +EG A +K Sbjct: 256 MKVFTNEGPTAFFK 269 Score = 33.1 bits (74), Expect = 0.63 Identities = 21/71 (29%), Positives = 33/71 (46%), Gaps = 4/71 (5%) Frame = +2 Query: 164 SGMLATCVIQPIDMIKVK-IQLGEG---SAAQVAKTMYANEGLGSFYKGLSAGLLRQATY 331 +G AT + P+D++K + I G S A ++ NEG +F+KGL LR ++ Sbjct: 222 AGFCATAMSSPVDVVKTRFINSPPGQYKSVPNCAMKVFTNEGPTAFFKGLVPSFLRLGSW 281 Query: 332 TTARLGSFRVL 364 F L Sbjct: 282 NVIMFVCFEQL 292
>UCP2_BRARE (Q9W720) Mitochondrial uncoupling protein 2 (UCP 2)| Length = 310 Score = 66.6 bits (161), Expect = 5e-11 Identities = 49/170 (28%), Positives = 76/170 (44%), Gaps = 15/170 (8%) Frame = +2 Query: 134 TIKPFVNGGASGMLATCVIQPIDMIKVKIQL-GEGSAAQ--------------VAKTMYA 268 T+K F+ G + +A P+D KV++Q+ GE A+ TM Sbjct: 14 TVK-FIGAGTAACIADLFTFPLDTAKVRLQIQGENKASTNMGRGPVKYRGVFGTISTMVR 72 Query: 269 NEGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAI 448 EG S Y GL AGL RQ ++ + R+G + + + +D + + G T GA+ Sbjct: 73 VEGPRSLYSGLVAGLQRQMSFASVRIGLYDSVKQFYTKGSDHAGIG--SRLMAGCTTGAM 130 Query: 449 GACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 V P D+ +R QA + A++R Y + A I +EG LWK Sbjct: 131 AVAVAQPTDVLKVRFQAQVSAGASKR--YHSTMDAYRTIAKEEGFRGLWK 178
>UCP5_MOUSE (Q9Z2B2) Brain mitochondrial carrier protein 1 (BMCP-1)| (Mitochondrial uncoupling protein 5) (UCP 5) (Solute carrier family 25 member 14) Length = 325 Score = 65.9 bits (159), Expect = 9e-11 Identities = 45/166 (27%), Positives = 78/166 (46%), Gaps = 13/166 (7%) Frame = +2 Query: 140 KPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAKT-------------MYANEGL 280 KPFV GG + ++A P+D+ K ++Q+ +G + V +Y EG+ Sbjct: 42 KPFVYGGLASIVAEFGTFPVDLTKTRLQV-QGQSIDVRFKEIKYRGMFHALFRIYKEEGI 100 Query: 281 GSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACV 460 + Y G++ LLRQA+Y T ++G ++ L +E + L + G+ +G I + + Sbjct: 101 LALYSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLI--NMICGVVSGVISSTI 158 Query: 461 GSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 +P D+ IRMQA +L + + I EG LW+ Sbjct: 159 ANPTDVLKIRMQAQGSL------FQGSMIGSFIDIYQQEGTRGLWR 198
>UCP5_HUMAN (O95258) Brain mitochondrial carrier protein 1 (BMCP-1)| (Mitochondrial uncoupling protein 5) (UCP 5) (Solute carrier family 25 member 14) Length = 325 Score = 65.5 bits (158), Expect = 1e-10 Identities = 45/165 (27%), Positives = 78/165 (47%), Gaps = 12/165 (7%) Frame = +2 Query: 140 KPFVNGGASGMLATCVIQPIDMIKVKIQL-GEGSAAQVAKTMYAN-----------EGLG 283 KPFV GG + ++A P+D+ K ++Q+ G+ A+ + Y EG+ Sbjct: 42 KPFVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVL 101 Query: 284 SFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVG 463 + Y G++ LLRQA+Y T ++G ++ L +E + L + G+ +G I + + Sbjct: 102 ALYSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLI--NMICGVVSGVISSTIA 159 Query: 464 SPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 +P D+ IRMQA +L + + I EG LW+ Sbjct: 160 NPTDVLKIRMQAQGSL------FQGSMIGSFIDIYQQEGTRGLWR 198
>UCP1_CANFA (Q9GMZ1) Mitochondrial brown fat uncoupling protein 1 (UCP 1)| (Thermogenin) Length = 309 Score = 64.3 bits (155), Expect = 3e-10 Identities = 43/154 (27%), Positives = 70/154 (45%), Gaps = 12/154 (7%) Frame = +2 Query: 173 LATCVIQPIDMIKVKIQL---GEGSAAQVAK---------TMYANEGLGSFYKGLSAGLL 316 LA + P+D KV++Q+ G+G + + T+ EGL Y GL AGL Sbjct: 26 LADMITFPLDTAKVRLQIQGEGQGQPPRAPRYRGVLGTVATLARTEGLQKLYSGLPAGLQ 85 Query: 317 RQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLALIRMQ 496 RQ + + R+G + + + + G L + G+ G +G P ++ +R+Q Sbjct: 86 RQVGFASLRIGLYDSV-REWLSPGQGAAASLGSRISAGVMTGGAAVFIGQPTEVVKVRLQ 144 Query: 497 ADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 A S L + R Y ++A I EG+ LWK Sbjct: 145 AQSHLHGRKPR-YTGTYNAYRIIATTEGLTGLWK 177
>ODC_PONPY (Q5RFB7) Mitochondrial 2-oxodicarboxylate carrier (Solute carrier| family 25 member 21) Length = 299 Score = 64.3 bits (155), Expect = 3e-10 Identities = 45/158 (28%), Positives = 75/158 (47%), Gaps = 8/158 (5%) Frame = +2 Query: 149 VNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAKTM-YANE-------GLGSFYKGLS 304 + G SG+ V+ P +++KV +Q + A+ T+ YA + GL KGL+ Sbjct: 114 IAGLGSGLTEAIVVNPFEVVKVGLQANRNTFAKQPSTVGYARQIIKKEGWGLQGLNKGLT 173 Query: 305 AGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLAL 484 A L R + G + + N I N L ++K IGL +G I + + P D+A Sbjct: 174 ATLGRHGVFNMVYFGFYYNVKN-MIPVNKDPTLEFLRKFGIGLLSGTIASVINIPFDVAK 232 Query: 485 IRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 R+Q +P + Y+ F + + +EG+LAL+K Sbjct: 233 SRIQGPQPVPGEIK--YRTCFKTMATVYQEEGILALYK 268 Score = 40.0 bits (92), Expect = 0.005 Identities = 30/140 (21%), Positives = 62/140 (44%), Gaps = 12/140 (8%) Frame = +2 Query: 140 KPFVNGGASGMLATCVIQPIDMIKVKIQL--------GEGSAAQVAKTMYANEGLGSFYK 295 + V GG++G++ C++ P+D++K + Q+ S + ++ E L FYK Sbjct: 15 RQIVAGGSAGLVEICLMHPLDVVKTRFQIQRCATDPNSYKSLVDSFRMIFQTERLFGFYK 74 Query: 296 GLSAGLLRQATYTTARLGSF----RVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVG 463 G+ +L + + +F ++L ++ P + GL +G A V Sbjct: 75 GILPPILAETPKRAVKFFTFEQYKKLLGYVSLS-------PALTFTIAGLGSGLTEAIVV 127 Query: 464 SPADLALIRMQADSTLPAAQ 523 +P ++ + +QA+ A Q Sbjct: 128 NPFEVVKVGLQANRNTFAKQ 147 Score = 30.4 bits (67), Expect = 4.1 Identities = 23/69 (33%), Positives = 34/69 (49%), Gaps = 8/69 (11%) Frame = +2 Query: 137 IKPFVNGGASGMLATCVIQPIDMIKVKIQ-----LGEGSAAQVAKTM---YANEGLGSFY 292 ++ F G SG +A+ + P D+ K +IQ GE KTM Y EG+ + Y Sbjct: 208 LRKFGIGLLSGTIASVINIPFDVAKSRIQGPQPVPGEIKYRTCFKTMATVYQEEGILALY 267 Query: 293 KGLSAGLLR 319 KGL ++R Sbjct: 268 KGLLPKIMR 276
>UCP2_CYPCA (Q9W725) Mitochondrial uncoupling protein 2 (UCP 2)| Length = 310 Score = 63.9 bits (154), Expect = 3e-10 Identities = 46/170 (27%), Positives = 71/170 (41%), Gaps = 15/170 (8%) Frame = +2 Query: 134 TIKPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQV---------------AKTMYA 268 T+K F+ G + +A P+D KV++Q+ S V TM Sbjct: 14 TVK-FIGAGTAACIADLFTFPLDTAKVRLQIQGESKIPVNTGHGPVKYRGVFGTISTMVR 72 Query: 269 NEGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAI 448 EG S Y GL AGL RQ ++ + R+G + + K + + + G T GA+ Sbjct: 73 VEGPRSLYSGLVAGLQRQMSFASVRIGLYDSV--KQFYTKGSEHVGIGSRLMAGCTTGAM 130 Query: 449 GACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 + P D+ +R QA ++ A + Y A I +EG LWK Sbjct: 131 AVALAQPTDVVKVRFQAQNS--AGANKRYHGTMDAYRTIAKEEGFRGLWK 178
>YG2O_YEAST (P53257) Putative mitochondrial carrier YGR096W| Length = 314 Score = 63.5 bits (153), Expect = 4e-10 Identities = 53/157 (33%), Positives = 80/157 (50%), Gaps = 12/157 (7%) Frame = +2 Query: 77 EEMADAKQQQAAAPTGVWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAA---- 244 EE + K Q AA WKT+ + G SG+LA + P+D IK+++QL + Sbjct: 4 EEDSLRKGQNVAA----WKTL---LAGAVSGLLARSITAPMDTIKIRLQLTPANGLKPFG 56 Query: 245 ----QVAKTMYANEGLGSFYKGLSAGLLRQATYTTARLGSF----RVLTNKAIEANDGRP 400 +VA++M NEG+ SF+KG G L TY +A+ S+ R LT +EA R Sbjct: 57 SQVMEVARSMIKNEGIRSFWKGNIPGSLLYVTYGSAQFSSYSLFNRYLTPFGLEA---RL 113 Query: 401 LPLVQKAFIGLTAGAIGACVGSPADLALIRMQADSTL 511 LV AF G+T+ + V P D+ R+ A++ + Sbjct: 114 HSLVVGAFAGITS----SIVSYPFDVLRTRLVANNQM 146 Score = 32.0 bits (71), Expect = 1.4 Identities = 28/137 (20%), Positives = 55/137 (40%), Gaps = 10/137 (7%) Frame = +2 Query: 116 PTGVWKTIKPFVNGGASGMLATCVIQPIDMIKVKI----QLGEGSAAQVAKTMYANEGLG 283 P G+ + V G +G+ ++ V P D+++ ++ Q+ S + + ++ EGL Sbjct: 106 PFGLEARLHSLVVGAFAGITSSIVSYPFDVLRTRLVANNQMHSMSITREVRDIWKLEGLP 165 Query: 284 SFYKGLSAGLLRQATYTTARLGSFRVL------TNKAIEANDGRPLPLVQKAFIGLTAGA 445 F+KG A + + G++ + K A+ L + + G G Sbjct: 166 GFFKGSIASMTTITLTASIMFGTYETIRIYCDENEKTTAAHKKWELATLNHS-AGTIGGV 224 Query: 446 IGACVGSPADLALIRMQ 496 I + P + RMQ Sbjct: 225 IAKIITFPLETIRRRMQ 241
>UCP1_BOVIN (P10861) Mitochondrial brown fat uncoupling protein 1 (UCP 1)| (Thermogenin) (Fragment) Length = 288 Score = 62.8 bits (151), Expect = 7e-10 Identities = 44/159 (27%), Positives = 71/159 (44%), Gaps = 10/159 (6%) Frame = +2 Query: 152 NGGASGMLATCVIQPIDMIKVKIQL-GEGSAAQVAK---------TMYANEGLGSFYKGL 301 + G + +A + P+D KV++Q+ GE + + T+ EG Y GL Sbjct: 3 SAGVAACVADIITFPLDTAKVRLQIQGECLISSAIRYKGVLGTIITLAKTEGPVKLYSGL 62 Query: 302 SAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLA 481 AGL RQ + + R+G + + G+ L K GL G + +G P ++ Sbjct: 63 PAGLQRQISLASLRIGLYDTVQEFF---TTGKEASLGSKISAGLMTGGVAVFIGQPTEVV 119 Query: 482 LIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 +R+QA S L + R Y ++A I EG+ LWK Sbjct: 120 KVRLQAQSHLHGPKPR-YTGTYNAYRIIATTEGLTGLWK 157
>UCP1_RABIT (P14271) Mitochondrial brown fat uncoupling protein 1 (UCP 1)| (Thermogenin) Length = 306 Score = 62.4 bits (150), Expect = 1e-09 Identities = 48/163 (29%), Positives = 76/163 (46%), Gaps = 14/163 (8%) Frame = +2 Query: 152 NGGASGMLATCVIQPIDMIKVKIQL-GE-------------GSAAQVAKTMYANEGLGSF 289 + G + LA + P+D KV+ Q+ GE G+ +AKT EG Sbjct: 19 SAGVAACLADVITFPLDTAKVRQQIQGEFPITSGIRYKGVLGTITTLAKT----EGPLKL 74 Query: 290 YKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSP 469 Y GL AGL RQ ++ + R+G + + + + + P L K GLT G + +G P Sbjct: 75 YSGLPAGLQRQISFASLRIGLYDTV-QEFFTSGEETP-SLGSKISAGLTTGGVAVFIGQP 132 Query: 470 ADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 ++ +R+QA S L + R Y ++A I E + +LWK Sbjct: 133 TEVVKVRLQAQSHLHGLKPR-YTGTYNAYRIIATTESLTSLWK 174 Score = 35.4 bits (80), Expect = 0.13 Identities = 23/84 (27%), Positives = 38/84 (45%), Gaps = 4/84 (4%) Frame = +2 Query: 146 FVNGGASGMLATCVIQPIDMIKVK-IQLGEGSAAQV---AKTMYANEGLGSFYKGLSAGL 313 FV+ +G T + P+D++K + I G A V A TM+ EG +F+KG Sbjct: 215 FVSALIAGFCTTLLSSPVDVVKTRFINSPPGQYASVPNCAMTMFTKEGPTAFFKGFVPSF 274 Query: 314 LRQATYTTARLGSFRVLTNKAIEA 385 LR ++ F L + + + Sbjct: 275 LRLGSWNVIMFVCFEKLKGELMRS 298
>ODC_HUMAN (Q9BQT8) Mitochondrial 2-oxodicarboxylate carrier (Solute carrier| family 25 member 21) Length = 299 Score = 62.4 bits (150), Expect = 1e-09 Identities = 45/158 (28%), Positives = 74/158 (46%), Gaps = 8/158 (5%) Frame = +2 Query: 149 VNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAKTM-YANE-------GLGSFYKGLS 304 + G SG+ V+ P +++KV +Q + A+ T+ YA + GL KGL+ Sbjct: 114 IAGLGSGLTEAIVVNPFEVVKVGLQANRNTFAEQPSTVGYARQIIKKEGWGLQGLNKGLT 173 Query: 305 AGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLAL 484 A L R + G + + N I N L +K IGL +G I + + P D+A Sbjct: 174 ATLGRHGVFNMVYFGFYYNVKN-MIPVNKDPILEFWRKFGIGLLSGTIASVINIPFDVAK 232 Query: 485 IRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 R+Q +P + Y+ F + + +EG+LAL+K Sbjct: 233 SRIQGPQPVPGEIK--YRTCFKTMATVYQEEGILALYK 268 Score = 43.9 bits (102), Expect = 4e-04 Identities = 32/140 (22%), Positives = 64/140 (45%), Gaps = 12/140 (8%) Frame = +2 Query: 140 KPFVNGGASGMLATCVIQPIDMIKVKIQL--------GEGSAAQVAKTMYANEGLGSFYK 295 + V GG++G++ C++ P+D++K + Q+ S + ++ EGL FYK Sbjct: 15 RQIVAGGSAGLVEICLMHPLDVVKTRFQIQRCATDPNSYKSLVDSFRMIFQMEGLFGFYK 74 Query: 296 GLSAGLLRQATYTTARLGSF----RVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVG 463 G+ +L + + +F ++L ++ P + A GL +G A V Sbjct: 75 GILPPILAETPKRAVKFFTFEQYKKLLGYVSLS-------PALTFAIAGLGSGLTEAIVV 127 Query: 464 SPADLALIRMQADSTLPAAQ 523 +P ++ + +QA+ A Q Sbjct: 128 NPFEVVKVGLQANRNTFAEQ 147 Score = 29.6 bits (65), Expect = 6.9 Identities = 23/68 (33%), Positives = 33/68 (48%), Gaps = 8/68 (11%) Frame = +2 Query: 140 KPFVNGGASGMLATCVIQPIDMIKVKIQ-----LGEGSAAQVAKTM---YANEGLGSFYK 295 + F G SG +A+ + P D+ K +IQ GE KTM Y EG+ + YK Sbjct: 209 RKFGIGLLSGTIASVINIPFDVAKSRIQGPQPVPGEIKYRTCFKTMATVYQEEGILALYK 268 Query: 296 GLSAGLLR 319 GL ++R Sbjct: 269 GLLPKIMR 276
>ODC_MOUSE (Q8BZ09) Mitochondrial 2-oxodicarboxylate carrier (Solute carrier| family 25 member 21) Length = 298 Score = 62.0 bits (149), Expect = 1e-09 Identities = 44/158 (27%), Positives = 75/158 (47%), Gaps = 8/158 (5%) Frame = +2 Query: 149 VNGGASGMLATCVIQPIDMIKVKIQLGEG------SAAQVAKTMYANEGLG--SFYKGLS 304 + G SG+ V+ P +++KV +Q+ S A+ + EGLG KGL+ Sbjct: 113 IAGLGSGLTEAVVVNPFEVVKVGLQVNRNLFKEQPSTFAYARQIIKKEGLGFQGLNKGLT 172 Query: 305 AGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLAL 484 A L R + G + + N I ++ L ++K IG +G +G+ P D+A Sbjct: 173 ATLGRHGIFNMVYFGFYHNVKN-IIPSSKDPTLEFLRKFGIGFVSGTMGSVFNIPFDVAK 231 Query: 485 IRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 R+Q +P + Y++ F + I +EG+LAL+K Sbjct: 232 SRIQGPQPVPGEIK--YRSCFKTMEMIYREEGILALYK 267 Score = 40.0 bits (92), Expect = 0.005 Identities = 29/135 (21%), Positives = 61/135 (45%), Gaps = 8/135 (5%) Frame = +2 Query: 131 KTIKPFVNGGASGMLATCVIQPIDMIKVKIQLGEG-SAAQVAKT-------MYANEGLGS 286 +T + GG++G++ C++ P+D++K + Q+ + Q +T ++ EGL Sbjct: 11 ETSRQVAAGGSAGLVEICLMHPLDVVKTRFQVQRSVTDPQSYRTVRGSFQMIFRTEGLFG 70 Query: 287 FYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGS 466 FYKG+ +L + + +F + + L + GL +G A V + Sbjct: 71 FYKGIIPPILAETPKRAVKFSTFELYKKFLGYMSLSPGLTFL---IAGLGSGLTEAVVVN 127 Query: 467 PADLALIRMQADSTL 511 P ++ + +Q + L Sbjct: 128 PFEVVKVGLQVNRNL 142
>MNCP_OXYFA (P15798) Macronuclear solute carrier homolog CR-MSC| Length = 371 Score = 61.6 bits (148), Expect = 2e-09 Identities = 49/163 (30%), Positives = 70/163 (42%), Gaps = 16/163 (9%) Frame = +2 Query: 146 FVNGGASGMLATCVIQPIDMIKVKIQ-LGEGSAA------------QVAKTMYA-NEGLG 283 F ++ QP+DM++++ Q L EG Q+ + +YA GL Sbjct: 22 FAAANVIALITHAATQPLDMVRIRSQMLQEGKTFSGLGYQKGWYPFQIMEEIYAAGGGLR 81 Query: 284 SFYKGLSAGLLRQATYTTARLGSFRVLTNKAIE--ANDGRPLPLVQKAFIGLTAGAIGAC 457 FY R YTTAR+ +F +K + RP LV +G G I Sbjct: 82 KFYSAFDTFFFRTVCYTTARVTAFGYFYDKVNKDPRRVARPDFLVAAGVLG---GFIAGV 138 Query: 458 VGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVL 586 V +P D+ RMQ D P A RR+Y N L ++ A+EG L Sbjct: 139 VTNPIDIVYNRMQVDELYPQAARRNYSNTIQGLAKV-AEEGAL 180
>SFC1_YEAST (P33303) Succinate/fumarate mitochondrial transporter (Regulator of| acetyl-CoA synthetase activity) Length = 322 Score = 61.2 bits (147), Expect = 2e-09 Identities = 45/173 (26%), Positives = 78/173 (45%), Gaps = 13/173 (7%) Frame = +2 Query: 119 TGVWKTIKPFVNGGASGML-ATCVIQPIDMIKVKIQLGE------------GSAAQVAKT 259 +G+ T FV G +G+ A V+ P++++K+++Q +A A T Sbjct: 105 SGIVSTGNTFVAGVGAGITEAVLVVNPMEVVKIRLQAQHLTPSEPNAGPKYNNAIHAAYT 164 Query: 260 MYANEGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTA 439 + EG+ + Y+G+S RQAT A + L + LP + + IGL + Sbjct: 165 IVKEEGVSALYRGVSLTAARQATNQGANFTVYSKLKEFLQNYHQMDVLPSWETSCIGLIS 224 Query: 440 GAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 GAIG +P D R+Q D ++ ++ K ++ +EG AL+K Sbjct: 225 GAIGPFSNAPLDTIKTRLQKDKSISLEKQSGMKKIITIGAQLLKEEGFRALYK 277 Score = 61.2 bits (147), Expect = 2e-09 Identities = 49/173 (28%), Positives = 75/173 (43%), Gaps = 17/173 (9%) Frame = +2 Query: 131 KTIKPFVN---GGASGMLATCVIQPIDMIKVKIQLGEGSAA----------QVAKTMYAN 271 K P +N GG +G+ P+D IKV++Q+ A + +T+Y Sbjct: 6 KASHPAINLMAGGTAGLFEALCCHPLDTIKVRMQIYRRVAGIEHVKPPGFIKTGRTIYQK 65 Query: 272 EGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFI-GLTAGAI 448 EG + YKGL A ++ R S+ + G + F+ G+ AG Sbjct: 66 EGFLALYKGLGAVVIGIIPKMAIRFSSYEFYRTLLVNKESG--IVSTGNTFVAGVGAGIT 123 Query: 449 GA-CVGSPADLALIRMQADSTLPAAQRR--HYKNAFHALYRITADEGVLALWK 598 A V +P ++ IR+QA P+ Y NA HA Y I +EGV AL++ Sbjct: 124 EAVLVVNPMEVVKIRLQAQHLTPSEPNAGPKYNNAIHAAYTIVKEEGVSALYR 176
>MNCP_OXYTR (Q27151) Macronuclear solute carrier homolog CR-MSC| Length = 371 Score = 60.8 bits (146), Expect = 3e-09 Identities = 49/163 (30%), Positives = 70/163 (42%), Gaps = 16/163 (9%) Frame = +2 Query: 146 FVNGGASGMLATCVIQPIDMIKVKIQ-LGEGSAA------------QVAKTMYA-NEGLG 283 F ++ QP+DM++++ Q L EG Q+ + +YA GL Sbjct: 22 FAAANVIALITHAATQPLDMVRIRSQMLQEGKTFSGLGYQKGWYPFQIMEEIYAAGGGLR 81 Query: 284 SFYKGLSAGLLRQATYTTARLGSFRVLTNKAIE--ANDGRPLPLVQKAFIGLTAGAIGAC 457 FY R YTTAR+ +F +K + RP LV +G G I Sbjct: 82 KFYSAFDTFFFRTVGYTTARVTAFGYFYDKVNKDPRRVARPDFLVAAGVLG---GFIAGV 138 Query: 458 VGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVL 586 V +P D+ RMQ D P A RR+Y N L ++ A+EG L Sbjct: 139 VTNPIDIVYNRMQVDELYPQAARRNYSNTVQGLAKV-AEEGAL 180
>CMC1_YEAST (P48233) Calcium-binding mitochondrial carrier SAL1 (Suppressor of| AAC2 lethality) Length = 545 Score = 58.9 bits (141), Expect = 1e-08 Identities = 49/168 (29%), Positives = 71/168 (42%), Gaps = 17/168 (10%) Frame = +2 Query: 146 FVNGGASGMLATCVIQPIDMIKVKIQL--------GEGSAAQVAKTMYANEGLGSFYKGL 301 ++ GG +GM A + PID +K ++Q G Q AK M+ GL FY+G+ Sbjct: 351 YIAGGLAGMAAQFSVYPIDTLKFRVQCAPLDTKLKGNNLLFQTAKDMFREGGLRLFYRGV 410 Query: 302 SAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAF---------IGLTAGAIGA 454 + G++ Y LG+F L K A + L L Q +G +G +GA Sbjct: 411 TVGIVGIFPYAALDLGTFSAL-KKWYIAKQAKTLNLPQDQVTLSNLVVLPMGAFSGTVGA 469 Query: 455 CVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 V P +L R+QA T A Y L + EG L+K Sbjct: 470 SVVYPINLLRTRLQAQGTY--AHPYVYNGFKDVLLKTLEREGYQGLFK 515
>BT1_MAIZE (P29518) Protein brittle-1, chloroplast precursor| Length = 436 Score = 57.8 bits (138), Expect = 2e-08 Identities = 42/158 (26%), Positives = 69/158 (43%), Gaps = 6/158 (3%) Frame = +2 Query: 143 PFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAKT---MYANEGLGSFYKGLSAGL 313 P V G +G +T P+++IK ++ + + VA + +EG Y+GL+ L Sbjct: 232 PLVAGALAGFASTLCTYPMELIKTRVTIEKDVYDNVAHAFVKILRDEGPSELYRGLTPSL 291 Query: 314 LRQATYTTARLGSFRVLTNKAIEANDGRP---LPLVQKAFIGLTAGAIGACVGSPADLAL 484 + Y ++ L A RP + V IG AGAI + P ++A Sbjct: 292 IGVVPYAACNFYAYETLKRLYRRATGRRPGADVGPVATLLIGSAAGAIASSATFPLEVAR 351 Query: 485 IRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 +MQ + R+ Y+N HA+Y I EG L++ Sbjct: 352 KQMQVGAV---GGRQVYQNVLHAIYCILKKEGAGGLYR 386 Score = 45.4 bits (106), Expect = 1e-04 Identities = 50/199 (25%), Positives = 81/199 (40%), Gaps = 23/199 (11%) Frame = +2 Query: 71 SPEEMADAKQQQAAAPTGVWKTIKP-----------FVNGGASGMLATCVIQPIDMIKVK 217 S EE A+ ++ + AA G + + V+G +G ++ + P++ I+ Sbjct: 102 SEEEEAEGRRHEEAAAAGRSEPEEGQGQDRQPAPARLVSGAIAGAVSRTFVAPLETIRTH 161 Query: 218 IQLGE---GSAAQVAKTMYANEGLGSFYKGLSAGLLRQA--------TYTTARLGSFRVL 364 + +G S A V + + NEG ++G + +LR A TY TA+ + L Sbjct: 162 LMVGSIGVDSMAGVFQWIMQNEGWTGLFRGNAVNVLRVAPSKAIEHFTYDTAK----KFL 217 Query: 365 TNKAIEAND-GRPLPLVQKAFIGLTAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKN 541 T K E P PLV GA G + L M+ T ++ Y N Sbjct: 218 TPKGDEPPKIPIPTPLVA-----------GALAGFASTLCTYPMELIKTRVTIEKDVYDN 266 Query: 542 AFHALYRITADEGVLALWK 598 HA +I DEG L++ Sbjct: 267 VAHAFVKILRDEGPSELYR 285
>ARG13_NEUCR (Q01356) Amino acid transporter arg-13| Length = 363 Score = 56.6 bits (135), Expect = 5e-08 Identities = 52/176 (29%), Positives = 79/176 (44%), Gaps = 28/176 (15%) Frame = +2 Query: 155 GGASGMLATCVIQPIDMIKVKIQLGE---GSAAQ--------VAKTMYANEGLGSFYKGL 301 GG SG + ++ P++++K KIQ+ + G+ A+ V K ++ +EGL F+ G Sbjct: 150 GGFSGAFTSLILTPVELVKCKIQVPDEPGGAGARQRQLKPIPVIKEIFRHEGLRGFWHGQ 209 Query: 302 SAGLLRQATYTTARLGS-------FRVLTNKA----------IEANDGRPLPLVQKAFIG 430 L+R+A A GS FR +A + A+ RPLPL Q+A G Sbjct: 210 LGTLIREAGGCAAWFGSKETTSKWFRGRNERALLKRGASQEEVVASRERPLPLWQQAIAG 269 Query: 431 LTAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 +AG + PAD RMQ S + K A + + + E ALWK Sbjct: 270 ASAGMSYNFLFFPADTVKSRMQT-SPIGGGGDNGGKGAATMMPKKSFGEEARALWK 324 Score = 37.4 bits (85), Expect = 0.033 Identities = 40/172 (23%), Positives = 69/172 (40%), Gaps = 13/172 (7%) Frame = +2 Query: 119 TGVWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQ-------LGEGSAAQVAKTMYANEG 277 T V + ++ V G A+G++ + P D +KV++Q L + +G Sbjct: 37 TAVMEALEDIVYGSAAGIVGKYIEYPFDTVKVRLQSQPDHLPLRYTGPLDCFRQSIRADG 96 Query: 278 LGSFYKGLSAGLLRQATYTTA-----RLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAG 442 Y+G+SA L+ A ++ R+G R L + A L L F G +G Sbjct: 97 FLGLYRGISAPLVGAALENSSLFFFERIG--RSLLYSSGFAPRDSELSLSALWFTGGFSG 154 Query: 443 AIGACVGSPADLALIRMQA-DSTLPAAQRRHYKNAFHALYRITADEGVLALW 595 A + + +P +L ++Q D A R+ + I EG+ W Sbjct: 155 AFTSLILTPVELVKCKIQVPDEPGGAGARQRQLKPIPVIKEIFRHEGLRGFW 206
>ODC_RAT (Q99JD3) Mitochondrial 2-oxodicarboxylate carrier (Solute carrier| family 25 member 21) Length = 298 Score = 55.8 bits (133), Expect = 9e-08 Identities = 40/158 (25%), Positives = 71/158 (44%), Gaps = 8/158 (5%) Frame = +2 Query: 149 VNGGASGMLATCVIQPIDMIKVKIQLGEG------SAAQVAKTMYANEGLG--SFYKGLS 304 + G SG+ V+ P +++KV +Q+ S A+ + EG G KG + Sbjct: 113 IAGLGSGLTEAVVVNPFEVVKVGLQVNRNMFTEQPSTFAYARQIIKKEGWGFQGLNKGFT 172 Query: 305 AGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLAL 484 A L R + G + + + + D L ++K IG +G +G+ P D+A Sbjct: 173 ATLGRHGIFNMTYFGFYYNVKDNIPSSKDPT-LEFLRKFGIGFVSGTVGSVFNIPFDVAK 231 Query: 485 IRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 R+Q +P + Y+ F + + +EG+LAL+K Sbjct: 232 SRIQGPQPVPGEIK--YRGCFKTMETVYREEGILALYK 267 Score = 43.9 bits (102), Expect = 4e-04 Identities = 28/137 (20%), Positives = 60/137 (43%), Gaps = 10/137 (7%) Frame = +2 Query: 131 KTIKPFVNGGASGMLATCVIQPIDMIKVKIQLGEG--------SAAQVAKTMYANEGLGS 286 +T + GG +G++ C++ P+D++K + Q+ S + ++ EGL Sbjct: 11 ETCRQVAAGGCAGLVEICLMHPLDVVKTRFQVQRSVTDPQSYKSLRDSFQVIFRTEGLFG 70 Query: 287 FYKGLSAGLLRQATYTTARLGSFRVLTN--KAIEANDGRPLPLVQKAFIGLTAGAIGACV 460 FYKG+ +L + + +F + + + G P+ GL +G A V Sbjct: 71 FYKGIIPPILAETPKRAVKFSTFELYKKFLGYMSLSPGLTFPIA-----GLGSGLTEAVV 125 Query: 461 GSPADLALIRMQADSTL 511 +P ++ + +Q + + Sbjct: 126 VNPFEVVKVGLQVNRNM 142
>TXTP_CAEEL (P34519) Putative tricarboxylate transport protein, mitochondrial| precursor (Citrate transport protein) (CTP) Length = 312 Score = 53.5 bits (127), Expect = 4e-07 Identities = 48/187 (25%), Positives = 78/187 (41%), Gaps = 15/187 (8%) Frame = +2 Query: 83 MADAKQQQAAAPTGVW-------KTIKPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSA 241 M+ + A P +W KT++ V GG +G + C+ P + +K ++QL E SA Sbjct: 1 MSGIQPVPGAKPLSMWQQYGPSEKTVRGIVIGGITGGIEICITFPTEYVKTQLQLDERSA 60 Query: 242 A-------QVAKTMYANEGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRP 400 K G Y+GLS L ++ R G+F L ++A A++ Sbjct: 61 TPKFRGPIDCVKQTVNGHGFFGLYRGLSVLLYGSIPKSSFRFGTFEYLKSQA--ADERGN 118 Query: 401 LPLVQKAFIGLTAGAIGACVG-SPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADE 577 L V + GL AG A +P + ++ D L + YK H + I E Sbjct: 119 LSPVMRLLCGLGAGLSEAVFAVTPMETVKVKFIHDQGLAQPK---YKGFVHGVGCIVKAE 175 Query: 578 GVLALWK 598 G+ ++K Sbjct: 176 GLGGIYK 182 Score = 50.1 bits (118), Expect = 5e-06 Identities = 43/175 (24%), Positives = 71/175 (40%), Gaps = 8/175 (4%) Frame = +2 Query: 98 QQQAAAPTGVWKTIKPFVNGGASGML-ATCVIQPIDMIKVKIQLGEGSAAQVAK------ 256 + QAA G + + G +G+ A + P++ +KVK +G A K Sbjct: 109 KSQAADERGNLSPVMRLLCGLGAGLSEAVFAVTPMETVKVKFIHDQGLAQPKYKGFVHGV 168 Query: 257 -TMYANEGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGL 433 + EGLG YKG++A + +Q + R L + ++ +P+ +G Sbjct: 169 GCIVKAEGLGGIYKGVTATMAKQGSNQAIRFFVMETLKDWYRGGDNTQPISKPIVGLMGA 228 Query: 434 TAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 AGA +P D+ RMQ + + YKN +I EG A +K Sbjct: 229 VAGAASVYGNTPIDVVKTRMQ------GLEAKKYKNTLDCAMQIWKKEGFFAFYK 277
>DNC_PONPY (Q5NVC1) Mitochondrial deoxynucleotide carrier (Solute carrier| family 25 member 19) Length = 320 Score = 53.5 bits (127), Expect = 4e-07 Identities = 47/163 (28%), Positives = 69/163 (42%), Gaps = 12/163 (7%) Frame = +2 Query: 146 FVNGGASGMLATCVIQPIDMIKVKIQL-GE----GSAAQVAKTMYANEGLGSFYKGLSAG 310 FV GG + +AT + P+D+++ + GE + TMY +EG FYKGL+ Sbjct: 122 FVCGGLAACMATLTVHPVDVLRTRFAAQGEPKVYNTLCHAVGTMYRSEGPQVFYKGLAPT 181 Query: 311 LLRQATYTTARL---GSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLA 481 L+ Y + S + L AI A +G+ +Q G AG I + P DL Sbjct: 182 LIAIFPYAGLQFSCYSSLKHLYKWAIPA-EGKKNENLQNLLCGSGAGVISKTLTYPLDLF 240 Query: 482 LIRMQADSTLPA----AQRRHYKNAFHALYRITADEGVLALWK 598 R+Q A Q R YK ++ EG L +K Sbjct: 241 KKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFK 283 Score = 38.1 bits (87), Expect = 0.020 Identities = 37/168 (22%), Positives = 63/168 (37%), Gaps = 18/168 (10%) Frame = +2 Query: 149 VNGGASGMLATCVIQPIDMIKVKIQLGEGSAA------------QVAKTMYANEGLGSFY 292 V G SG++ +I P D+IK++ QL + Q ++ + EG +F+ Sbjct: 20 VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPNAKYHGILQASRQILQEEGPTAFW 79 Query: 293 KGLSAGLLRQATYTTARLGSFRVLTNKAIEAN--DGRPLPLVQKAFIGLTAGAIGACVGS 466 KG + Y + SF +LT + D R + G + AC+ + Sbjct: 80 KGHIPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFS------VHFVCGGLAACMAT 133 Query: 467 ----PADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 P D+ R A + + Y HA+ + EG +K Sbjct: 134 LTVHPVDVLRTRFAAQ-----GEPKVYNTLCHAVGTMYRSEGPQVFYK 176 Score = 34.7 bits (78), Expect = 0.22 Identities = 21/74 (28%), Positives = 35/74 (47%), Gaps = 14/74 (18%) Frame = +2 Query: 155 GGASGMLATCVIQPIDMIKVKIQLGEGSAAQVA--------------KTMYANEGLGSFY 292 G +G+++ + P+D+ K ++Q+G A+ A K + EG F+ Sbjct: 223 GSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFF 282 Query: 293 KGLSAGLLRQATYT 334 KGLS LL+ A T Sbjct: 283 KGLSPSLLKAALST 296
>ODC2_YEAST (Q99297) Mitochondrial 2-oxodicarboxylate carrier 2| Length = 307 Score = 53.5 bits (127), Expect = 4e-07 Identities = 45/156 (28%), Positives = 73/156 (46%), Gaps = 8/156 (5%) Frame = +2 Query: 155 GGASGMLATCVIQPIDMIKVKIQLGEGS---AAQVAKTMYANEGLGSFYKGLSAGLLRQA 325 G ++GM VI P ++IK+++Q + S K NEG+ YKG+ + + R A Sbjct: 125 GASAGMTEAAVIVPFELIKIRMQDVKSSYLGPMDCLKKTIKNEGIMGLYKGIESTMWRNA 184 Query: 326 TYTTARLG-SFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVG----SPADLALIR 490 + G ++V + + G QK L AGAIG VG +P D+ R Sbjct: 185 LWNGGYFGVIYQVRNSMPVAKTKG------QKTRNDLIAGAIGGTVGTMLNTPFDVVKSR 238 Query: 491 MQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 +Q+ + +A ++ Y +L I +EG AL+K Sbjct: 239 IQSVDAVSSAVKK-YNWCLPSLLVIYREEGFRALYK 273 Score = 33.5 bits (75), Expect = 0.48 Identities = 21/76 (27%), Positives = 31/76 (40%), Gaps = 5/76 (6%) Frame = +2 Query: 386 NDGRPLPLVQKAFIGLTAGAIGACVGSPADLALIRMQADSTLPAA-----QRRHYKNAFH 550 ++ +PLP + + G AG V P D+ R Q + T P A Q Y Sbjct: 5 SNAKPLPFIYQFISGAVAGISELTVMYPLDVVKTRFQLEVTTPTAAAVGKQVERYNGVID 64 Query: 551 ALYRITADEGVLALWK 598 L +I EG L++ Sbjct: 65 CLKKIVKKEGFSRLYR 80
>DNC_HUMAN (Q9HC21) Mitochondrial deoxynucleotide carrier (Solute carrier| family 25 member 19) (Mitochondrial uncoupling protein 1) Length = 320 Score = 53.1 bits (126), Expect = 6e-07 Identities = 47/163 (28%), Positives = 69/163 (42%), Gaps = 12/163 (7%) Frame = +2 Query: 146 FVNGGASGMLATCVIQPIDMIKVKIQL-GEGSAAQVAK----TMYANEGLGSFYKGLSAG 310 FV GG + +AT + P+D+++ + GE + TMY +EG FYKGL+ Sbjct: 122 FVCGGLAACMATLTVHPVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPT 181 Query: 311 LLRQATYTTARL---GSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLA 481 L+ Y + S + L AI A +G+ +Q G AG I + P DL Sbjct: 182 LIAIFPYAGLQFSCYSSLKHLYKWAIPA-EGKKNENLQNLLCGSGAGVISKTLTYPLDLF 240 Query: 482 LIRMQADSTLPA----AQRRHYKNAFHALYRITADEGVLALWK 598 R+Q A Q R YK ++ EG L +K Sbjct: 241 KKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFK 283 Score = 38.1 bits (87), Expect = 0.020 Identities = 39/168 (23%), Positives = 65/168 (38%), Gaps = 18/168 (10%) Frame = +2 Query: 149 VNGGASGMLATCVIQPIDMIKVKIQL-------GEGSA-----AQVAKTMYANEGLGSFY 292 V G SG++ +I P D+IK++ QL + SA Q ++ + EG +F+ Sbjct: 20 VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79 Query: 293 KGLSAGLLRQATYTTARLGSFRVLTNKAIEAN--DGRPLPLVQKAFIGLTAGAIGACVGS 466 KG + Y + SF +LT + D R + G + AC+ + Sbjct: 80 KGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFS------VHFVCGGLAACMAT 133 Query: 467 ----PADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 P D+ R A + + Y HA+ + EG +K Sbjct: 134 LTVHPVDVLRTRFAAQ-----GEPKVYNTLRHAVGTMYRSEGPQVFYK 176 Score = 35.8 bits (81), Expect = 0.097 Identities = 23/86 (26%), Positives = 38/86 (44%), Gaps = 14/86 (16%) Frame = +2 Query: 155 GGASGMLATCVIQPIDMIKVKIQLGEGSAAQVA--------------KTMYANEGLGSFY 292 G +G+++ + P+D+ K ++Q+G A+ A K + EG F+ Sbjct: 223 GSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFF 282 Query: 293 KGLSAGLLRQATYTTARLGSFRVLTN 370 KGLS LL+ A T S+ N Sbjct: 283 KGLSPSLLKAALSTGFMFFSYEFFCN 308
>YMC2_YEAST (P38087) Carrier protein YMC2, mitochondrial precursor| Length = 329 Score = 52.0 bits (123), Expect = 1e-06 Identities = 38/169 (22%), Positives = 72/169 (42%), Gaps = 17/169 (10%) Frame = +2 Query: 131 KTIKPFVNGGASGMLATCVIQPIDMIKVKIQLG--EGSAAQVAKTMYANEGLGSFYKGLS 304 + +K G G+ V QP D KV++Q + +V + + NEG+ +FYKG Sbjct: 33 RVLKDIFAGTIGGIAQVLVGQPFDTTKVRLQTATTRTTTLEVLRNLVKNEGVFAFYKGAL 92 Query: 305 AGLLRQATYTTARLGSFRVL---------------TNKAIEANDGRPLPLVQKAFIGLTA 439 LL + + G + +++ ++ + LPL Q GLT Sbjct: 93 TPLLGVGICVSVQFGVNEAMKRFFQNYNASKNPNMSSQDVDLSRSNTLPLSQYYVCGLTG 152 Query: 440 GAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVL 586 G + + + SP + IR+Q ++ R +K + + ++ A G++ Sbjct: 153 GVVNSFLASPIEQIRIRLQTQTS--NGGDREFKGPWDCIKKLKAQGGLM 199 Score = 42.7 bits (99), Expect = 8e-04 Identities = 24/77 (31%), Positives = 40/77 (51%), Gaps = 7/77 (9%) Frame = +2 Query: 155 GGASGMLATCVIQPIDMIKVKIQLGE-------GSAAQVAKTMYANEGLGSFYKGLSAGL 313 G SG + + P+D++K IQ + S + VAKT+YA EG+ +F+KG + Sbjct: 246 GAFSGTMLWLTVYPLDVVKSIIQNDDLRKPKYKNSISYVAKTIYAKEGIRAFFKGFGPTM 305 Query: 314 LRQATYTTARLGSFRVL 364 +R A A +F ++ Sbjct: 306 VRSAPVNGATFLTFELV 322
>CMC1_DROME (Q9VA73) Calcium-binding mitochondrial carrier Aralar1| Length = 695 Score = 51.6 bits (122), Expect = 2e-06 Identities = 43/151 (28%), Positives = 70/151 (46%), Gaps = 3/151 (1%) Frame = +2 Query: 155 GGASGMLATCVIQPIDMIKVKIQL-GE-GSAAQVAKTMYANE-GLGSFYKGLSAGLLRQA 325 GG +G P++++K+++Q+ GE S +++ E GL YKG A LLR Sbjct: 448 GGCAGASQVVFTNPLEIVKIRLQVAGEIASGSKIRAWSVVRELGLFGLYKGARACLLRDV 507 Query: 326 TYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLALIRMQADS 505 ++ ++ T + DG PL A G AG A + +PAD+ R+Q Sbjct: 508 PFSAIYFPTY-AHTKAMMADKDGYNHPLTLLA-AGAIAGVPAASLVTPADVIKTRLQV-- 563 Query: 506 TLPAAQRRHYKNAFHALYRITADEGVLALWK 598 + + + Y + A +I A+EG A WK Sbjct: 564 -VARSGQTTYTGVWDATKKIMAEEGPRAFWK 593 Score = 35.0 bits (79), Expect = 0.17 Identities = 23/90 (25%), Positives = 40/90 (44%) Frame = +2 Query: 329 YTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLALIRMQADST 508 + T RL + + + A + + L + +G AGA+GA V P DL RMQ Sbjct: 316 HMTHRLAEIKAVESPADRSAFIQVLESSYRFTLGSFAGAVGATVVYPIDLVKTRMQNQRA 375 Query: 509 LPAAQRRHYKNAFHALYRITADEGVLALWK 598 Y+N++ ++ EG + L++ Sbjct: 376 GSYIGEVAYRNSWDCFKKVVRHEGFMGLYR 405
>DNC_MACFA (Q5IS35) Mitochondrial deoxynucleotide carrier (Solute carrier| family 25 member 19) Length = 320 Score = 51.6 bits (122), Expect = 2e-06 Identities = 44/162 (27%), Positives = 66/162 (40%), Gaps = 11/162 (6%) Frame = +2 Query: 146 FVNGGASGMLATCVIQPIDMIKVKIQL-GEGSAAQVAK----TMYANEGLGSFYKGLSAG 310 FV GG + AT + P+D+++ + GE + TMY +EG FYKGL+ Sbjct: 122 FVCGGLAACTATLTVHPVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPT 181 Query: 311 LLRQATYTTARLGSFRVLTN--KAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLAL 484 L+ Y + + L + K +G+ +Q G AG I + P DL Sbjct: 182 LIAIFPYAGLQFSCYSSLKHLYKWAMPAEGKKNENLQNLLCGSGAGVISKTLTYPLDLFK 241 Query: 485 IRMQADSTLPA----AQRRHYKNAFHALYRITADEGVLALWK 598 R+Q A Q R YK ++ EG L +K Sbjct: 242 KRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFK 283 Score = 40.0 bits (92), Expect = 0.005 Identities = 38/168 (22%), Positives = 63/168 (37%), Gaps = 18/168 (10%) Frame = +2 Query: 149 VNGGASGMLATCVIQPIDMIKVKIQLGEGSAA------------QVAKTMYANEGLGSFY 292 V G SG++ +I P D+IK++ QL + Q ++ + EGL +F+ Sbjct: 20 VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRRDPNAKYHGIFQASRQILQEEGLTAFW 79 Query: 293 KGLSAGLLRQATYTTARLGSFRVLTNKAIEAN--DGRPLPLVQKAFIGLTAGAIGACVGS 466 KG + Y + SF +LT + D R + G + AC + Sbjct: 80 KGHIPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFS------VHFVCGGLAACTAT 133 Query: 467 ----PADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 P D+ R A + + Y HA+ + EG +K Sbjct: 134 LTVHPVDVLRTRFAAQ-----GEPKVYNTLRHAVGTMYRSEGPQVFYK 176 Score = 34.7 bits (78), Expect = 0.22 Identities = 21/74 (28%), Positives = 35/74 (47%), Gaps = 14/74 (18%) Frame = +2 Query: 155 GGASGMLATCVIQPIDMIKVKIQLGEGSAAQVA--------------KTMYANEGLGSFY 292 G +G+++ + P+D+ K ++Q+G A+ A K + EG F+ Sbjct: 223 GSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFF 282 Query: 293 KGLSAGLLRQATYT 334 KGLS LL+ A T Sbjct: 283 KGLSPSLLKAALST 296
>COLT_DROME (Q9VQG4) Congested-like trachea protein| Length = 306 Score = 51.2 bits (121), Expect = 2e-06 Identities = 41/160 (25%), Positives = 70/160 (43%), Gaps = 9/160 (5%) Frame = +2 Query: 146 FVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQ--------VAKTMYANEGLGSFYKGL 301 FV G SG+ +T ++ P + IKV +Q +G + A +Y GL S +KG Sbjct: 119 FVAGSFSGLFSTLIMAPGERIKVLLQTQQGQGGERKYNGMIDCAGKLYKEGGLRSVFKGS 178 Query: 302 SAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLA 481 A +LR + L + A ++ + F G AG +G PAD+ Sbjct: 179 CATMLRDLPANGLYFLVYEALQDVAKSKSETGQISTASTIFAGGVAGMAYWILGMPADVL 238 Query: 482 LIRMQADSTLPAAQRRHYKNAFHALYR-ITADEGVLALWK 598 R+Q +A YK+ ++++ + +G LAL++ Sbjct: 239 KSRLQ------SAPEGTYKHGIRSVFKDLIVKDGPLALYR 272 Score = 37.4 bits (85), Expect = 0.033 Identities = 37/165 (22%), Positives = 64/165 (38%), Gaps = 11/165 (6%) Frame = +2 Query: 137 IKPFVNGGASGMLATCVIQPIDMIKVKIQ-----------LGEGSAAQVAKTMYANEGLG 283 +K F+ GG G+ P+D IKV++Q L G+ AKT+ NEG+ Sbjct: 16 VKSFLTGGFGGICNVLSGHPLDTIKVRLQTMPRPAPGEQPLYRGTFDCAAKTI-KNEGVR 74 Query: 284 SFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVG 463 YKG+SA L A + L + + + L Q G +G + Sbjct: 75 GLYKGMSAPLTGVAPIFAMCFAGY-ALGKRLQQRGEDAKLTYPQIFVAGSFSGLFSTLIM 133 Query: 464 SPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 +P + + +Q R Y ++ + G+ +++K Sbjct: 134 APGERIKVLLQTQQ--GQGGERKYNGMIDCAGKLYKEGGLRSVFK 176
>GDC_BOVIN (Q01888) Grave disease carrier protein (GDC) (Mitochondrial solute| carrier protein homolog) (Solute carrier family 25 member 16) Length = 330 Score = 51.2 bits (121), Expect = 2e-06 Identities = 46/155 (29%), Positives = 68/155 (43%), Gaps = 20/155 (12%) Frame = +2 Query: 122 GVWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQL---GEGSAAQVA---KTMYANEG-- 277 GV + + G +GM A P+DM++V++ GE + + KT+YA EG Sbjct: 124 GVSGHVHRLMAGSMAGMTAVICTYPLDMVRVRLAFQVKGEHTYTGIIHAFKTIYAKEGGF 183 Query: 278 LGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIE--------ANDGRPLPLVQKAFIGL 433 LG FY+GL +L A Y +F L + + + P LV K I L Sbjct: 184 LG-FYRGLMPTILGMAPYAGVSFFTFGTLKSVGLSYAPTLLGRPSSDNPNVLVLKTHINL 242 Query: 434 ----TAGAIGACVGSPADLALIRMQADSTLPAAQR 526 AGAI + P D+ RMQ + LP ++ Sbjct: 243 LCGGVAGAIAQTISYPFDVTRRRMQLGAVLPEFEK 277 Score = 36.6 bits (83), Expect = 0.057 Identities = 34/158 (21%), Positives = 55/158 (34%), Gaps = 10/158 (6%) Frame = +2 Query: 137 IKPFVNGGASGMLATCVIQPIDMIKVKIQLGEG-----SAAQVAKTMYANEGLGSFYKGL 301 ++ F+ GG +G A + P+D +KV +Q + + EG YKG Sbjct: 35 LRSFLAGGIAGCCAKTTVAPLDRVKVLLQAHNHHYRHLGVFSTLRAVPKKEGYLGLYKGN 94 Query: 302 SAGLLRQATYTTARLGSFR-----VLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGS 466 A ++R Y + +F + T + + V + G AG Sbjct: 95 GAMMIRIFPYGAIQFMAFEHYKTLITTKLGVSGH-------VHRLMAGSMAGMTAVICTY 147 Query: 467 PADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEG 580 P D+ +R+ Y HA I A EG Sbjct: 148 PLDMVRVRL----AFQVKGEHTYTGIIHAFKTIYAKEG 181 Score = 29.6 bits (65), Expect = 6.9 Identities = 20/74 (27%), Positives = 35/74 (47%), Gaps = 9/74 (12%) Frame = +2 Query: 125 VWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQLGEG--------SAAQVAKTMYANEGL 280 V KT + GG +G +A + P D+ + ++QLG + + K +Y + G+ Sbjct: 235 VLKTHINLLCGGVAGAIAQTISYPFDVTRRRMQLGAVLPEFEKCLTMRETMKYVYGHHGI 294 Query: 281 -GSFYKGLSAGLLR 319 Y+GLS +R Sbjct: 295 RKGLYRGLSLNYIR 308
>MPCP_HUMAN (Q00325) Phosphate carrier protein, mitochondrial precursor (PTP)| (Solute carrier family 25 member 3) Length = 362 Score = 50.8 bits (120), Expect = 3e-06 Identities = 44/161 (27%), Positives = 67/161 (41%), Gaps = 14/161 (8%) Frame = +2 Query: 119 TGVWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSA---AQVAKTMYANEGLGSF 289 T +W+T ++ A + P++ KV+IQ G A A MY EGL +F Sbjct: 157 TYLWRTSLYLAASASAEFFADIALAPMEAAKVRIQTQPGYANTLRDAAPKMYKEEGLKAF 216 Query: 290 YKGLSAGLLRQATYTTARLGSFRVLTNKAI--------EANDGRPLPLVQKAFIGLTAGA 445 YKG++ +RQ YT + F T +A+ + +P LV G AG Sbjct: 217 YKGVAPLWMRQIPYTMMKFACFE-RTVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGV 275 Query: 446 IGACVGSPAD---LALIRMQADSTLPAAQRRHYKNAFHALY 559 A V PAD L + + S +R +K + L+ Sbjct: 276 FCAIVSHPADSVVSVLNKEKGSSASLVLKRLGFKGVWKGLF 316
>MCATL_HUMAN (Q8N8R3) Mitchondrial carnitine/acylcarnitine carrier protein CACL| (CACT-like) (Solute carrier family 25 member 29) Length = 303 Score = 50.8 bits (120), Expect = 3e-06 Identities = 37/149 (24%), Positives = 67/149 (44%), Gaps = 7/149 (4%) Frame = +2 Query: 137 IKPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAK-------TMYANEGLGSFYK 295 + F+ G A+G + + P+++ K ++QL + A+ K +Y +EGL + Sbjct: 93 LNQFLAGAAAGAIQCVICCPMELAKTRLQLQDAGPARTYKGSLDCLAQIYGHEGLRGVNR 152 Query: 296 GLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPAD 475 G+ + LLR+ ++ LT +A+ G L + + G T+G + P D Sbjct: 153 GMVSTLLRETPSFGVYFLTYDALT-RALGCEPGDRLLVPKLLLAGGTSGIVSWLSTYPVD 211 Query: 476 LALIRMQADSTLPAAQRRHYKNAFHALYR 562 + R+QAD A + R + H YR Sbjct: 212 VVKSRLQADGLRGAPRYRGILDCVHQSYR 240 Score = 48.9 bits (115), Expect = 1e-05 Identities = 45/152 (29%), Positives = 67/152 (44%), Gaps = 6/152 (3%) Frame = +2 Query: 146 FVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAKTMYA------NEGLGSFYKGLSA 307 F+ G A G+ V P D +KV++Q+ Q T++ E + YKGL + Sbjct: 5 FLAGCAGGVAGVLVGHPFDTVKVRLQVQSVEKPQYRGTLHCFKSIIKQESVLGLYKGLGS 64 Query: 308 GLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLALI 487 L+ T+ A + + T +A+ G PL Q G AGAI + P +LA Sbjct: 65 PLM-GLTFINALVFGVQGNTLRAL----GHDSPLNQ-FLAGAAAGAIQCVICCPMELAKT 118 Query: 488 RMQADSTLPAAQRRHYKNAFHALYRITADEGV 583 R+Q PA R YK + L +I EG+ Sbjct: 119 RLQLQDAGPA---RTYKGSLDCLAQIYGHEGL 147 Score = 29.6 bits (65), Expect = 6.9 Identities = 22/86 (25%), Positives = 36/86 (41%), Gaps = 7/86 (8%) Frame = +2 Query: 140 KPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAA-------QVAKTMYANEGLGSFYKG 298 K + GG SG+++ P+D++K ++Q A Y EG F +G Sbjct: 191 KLLLAGGTSGIVSWLSTYPVDVVKSRLQADGLRGAPRYRGILDCVHQSYRAEGWRVFTRG 250 Query: 299 LSAGLLRQATYTTARLGSFRVLTNKA 376 L++ LLR A + V+ A Sbjct: 251 LASTLLRAFPVNAATFATVTVVLTYA 276
>MCATL_MOUSE (Q8BL03) Mitchondrial carnitine/acylcarnitine carrier protein CACL| (CACT-like) (Solute carrier family 25 member 29) Length = 306 Score = 50.8 bits (120), Expect = 3e-06 Identities = 45/152 (29%), Positives = 70/152 (46%), Gaps = 6/152 (3%) Frame = +2 Query: 146 FVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAKTMYA------NEGLGSFYKGLSA 307 F+ G A G+ V P D++KV++Q+ Q T++ E + YKGL + Sbjct: 5 FLAGCAGGVAGVIVGHPFDIVKVRLQVQSTEKPQYRGTLHCFQSIIKQESVLGLYKGLGS 64 Query: 308 GLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLALI 487 L+ T+ A + + T +A+ G+ PL Q G AGAI + P +LA Sbjct: 65 PLM-GLTFINALVFGVQGNTLRAL----GQDSPLNQ-FLAGAAAGAIQCVICCPMELAKT 118 Query: 488 RMQADSTLPAAQRRHYKNAFHALYRITADEGV 583 R+Q + PA R YK + L +I EG+ Sbjct: 119 RLQLQAVGPA---RTYKGSLDCLVQIYRHEGL 147 Score = 41.6 bits (96), Expect = 0.002 Identities = 32/129 (24%), Positives = 59/129 (45%), Gaps = 7/129 (5%) Frame = +2 Query: 137 IKPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAK-------TMYANEGLGSFYK 295 + F+ G A+G + + P+++ K ++QL A+ K +Y +EGL + Sbjct: 93 LNQFLAGAAAGAIQCVICCPMELAKTRLQLQAVGPARTYKGSLDCLVQIYRHEGLRGINR 152 Query: 296 GLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPAD 475 G+ + LLR+ ++ V+T +A+ G L + + G T+G P D Sbjct: 153 GMVSTLLRETPSFGVYFLTYDVMT-RAMGCEPGDRLLVPKLLLAGGTSGITSWLSTYPMD 211 Query: 476 LALIRMQAD 502 + R+QAD Sbjct: 212 VVKSRLQAD 220 Score = 38.1 bits (87), Expect = 0.020 Identities = 19/57 (33%), Positives = 26/57 (45%) Frame = +2 Query: 428 GLTAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 G G G VG P D+ +R+Q ST ++ Y+ H I E VL L+K Sbjct: 8 GCAGGVAGVIVGHPFDIVKVRLQVQST----EKPQYRGTLHCFQSIIKQESVLGLYK 60 Score = 32.0 bits (71), Expect = 1.4 Identities = 27/120 (22%), Positives = 51/120 (42%), Gaps = 7/120 (5%) Frame = +2 Query: 140 KPFVNGGASGMLATCVIQPIDMIKVKIQLG--EGS-----AAQVAKTMYANEGLGSFYKG 298 K + GG SG+ + P+D++K ++Q +G+ + Y EG F +G Sbjct: 191 KLLLAGGTSGITSWLSTYPMDVVKSRLQADGLQGTPRYRGIVDCMRQSYQAEGWQVFTRG 250 Query: 299 LSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADL 478 L++ LLR A + V+ + G + +A +G + G+ + P+ L Sbjct: 251 LASTLLRAFPVNAATFATVTVV----LTYTRGEEAQVDSEAALGTSPTPAGSALAQPSSL 306
>MPCP_MOUSE (Q8VEM8) Phosphate carrier protein, mitochondrial precursor (PTP)| (Solute carrier family 25 member 3) Length = 357 Score = 50.4 bits (119), Expect = 4e-06 Identities = 41/160 (25%), Positives = 67/160 (41%), Gaps = 13/160 (8%) Frame = +2 Query: 119 TGVWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSA---AQVAKTMYANEGLGSF 289 T +W+T + ++ A + P++ KV+IQ G A + MY EGL +F Sbjct: 152 TYLWRTSLYLASSASAEFFADIALAPMEAAKVRIQTQPGYANTLREAVPKMYKEEGLNAF 211 Query: 290 YKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKA-------FIGLTAGAI 448 YKG++ +RQ YT + F + +P KA G AG Sbjct: 212 YKGVAPLWMRQIPYTMMKFACFERTVEALYKFVVPKPRSECTKAEQLVVTFVAGYIAGVF 271 Query: 449 GACVGSPAD--LALIRMQADSTL-PAAQRRHYKNAFHALY 559 A V PAD ++++ + ST QR ++ + L+ Sbjct: 272 CAIVSHPADSVVSVLNKEKGSTASQVLQRLGFRGVWKGLF 311
>DNC_MOUSE (Q9DAM5) Mitochondrial deoxynucleotide carrier (Solute carrier| family 25 member 19) Length = 318 Score = 50.1 bits (118), Expect = 5e-06 Identities = 41/162 (25%), Positives = 67/162 (41%), Gaps = 11/162 (6%) Frame = +2 Query: 146 FVNGGASGMLATCVIQPIDMIKVKIQL-GE----GSAAQVAKTMYANEGLGSFYKGLSAG 310 FV GG S AT + P+D+++ ++ GE + + +TMY EG FYKGL+ Sbjct: 122 FVCGGLSAGTATLTVHPVDVLRTRLAAQGEPKIYNNLREAIRTMYKTEGPFVFYKGLTPT 181 Query: 311 LLRQATYTTARLGSFRVLTNKA--IEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLAL 484 ++ Y + +R L + DG+ ++ G +G I P DL Sbjct: 182 VIAIFPYAGLQFSCYRSLKRAYDWLIPPDGKQTGNLKNLLCGCGSGVISKTFTYPLDLIK 241 Query: 485 IRMQADSTLPA----AQRRHYKNAFHALYRITADEGVLALWK 598 R+Q A Q R Y+ ++ +EG +K Sbjct: 242 KRLQVGGFEHARSAFGQVRSYRGLLDLTQQVLQEEGTRGFFK 283 Score = 38.5 bits (88), Expect = 0.015 Identities = 37/162 (22%), Positives = 61/162 (37%), Gaps = 12/162 (7%) Frame = +2 Query: 149 VNGGASGMLATCVIQPIDMIKVKIQL-------GEGSAA-----QVAKTMYANEGLGSFY 292 V G SG + +I P+D+IK++ QL + +A Q AK + EG +F+ Sbjct: 20 VAGSVSGFVTRALISPLDVIKIRFQLQIERLCPSDPNAKYHGIFQAAKQILQEEGPRAFW 79 Query: 293 KGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPA 472 KG + Y + +F LT +AN + G + P Sbjct: 80 KGHVPAQILSIGYGAVQFLAFEELTELLYQANLYQTHQFSAHFVCGGLSAGTATLTVHPV 139 Query: 473 DLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 D+ R+ A + + Y N A+ + EG +K Sbjct: 140 DVLRTRLAAQ-----GEPKIYNNLREAIRTMYKTEGPFVFYK 176 Score = 34.3 bits (77), Expect = 0.28 Identities = 22/80 (27%), Positives = 38/80 (47%), Gaps = 14/80 (17%) Frame = +2 Query: 137 IKPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVA--------------KTMYANE 274 +K + G SG+++ P+D+IK ++Q+G A+ A + + E Sbjct: 217 LKNLLCGCGSGVISKTFTYPLDLIKKRLQVGGFEHARSAFGQVRSYRGLLDLTQQVLQEE 276 Query: 275 GLGSFYKGLSAGLLRQATYT 334 G F+KGLS L++ A T Sbjct: 277 GTRGFFKGLSPSLMKAALST 296
>YD1K_SCHPO (Q10248) Putative mitochondrial carrier C4G9.20c| Length = 302 Score = 50.1 bits (118), Expect = 5e-06 Identities = 40/164 (24%), Positives = 70/164 (42%), Gaps = 6/164 (3%) Frame = +2 Query: 125 VWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQLGE------GSAAQVAKTMYANEGLGS 286 V+ K F+ G + G+ V QP D +KV++Q +A K + NEGL + Sbjct: 14 VFSFTKDFLAGVSGGVAQVLVGQPFDCVKVRLQSQSNVSPIYNNALDCVKKISKNEGLAA 73 Query: 287 FYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGS 466 FYKG LL + + +F K + DG P+ + Q G +G + + Sbjct: 74 FYKGTVLPLLGIGFCVSIQFTTFEYC--KRFFSRDGTPVTMPQYYVSGAISGLANSFLVG 131 Query: 467 PADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 P + IR+Q + + Y + + +I++ G+ + K Sbjct: 132 PVEHVRIRLQ----IQTGKNVLYHGPWDCIKKISSQYGLSGIMK 171
>YMC1_YEAST (P32331) Carrier protein YMC1, mitochondrial precursor| Length = 307 Score = 50.1 bits (118), Expect = 5e-06 Identities = 37/134 (27%), Positives = 61/134 (45%), Gaps = 9/134 (6%) Frame = +2 Query: 131 KTIKPFVNGGASGMLATCVIQPIDMIKVKIQLGEG--SAAQVAKTMYANEGLGSFYKGLS 304 + +K + G A G+ V QP D KV++Q +A +V + + ANEG FYKG Sbjct: 24 RVVKDLLAGTAGGIAQVLVGQPFDTTKVRLQTSSTPTTAMEVVRKLLANEGPRGFYKGTL 83 Query: 305 AGLLRQATYTTARLGSFRVLTNKAIE-------ANDGRPLPLVQKAFIGLTAGAIGACVG 463 L+ + + G N+A++ A+ L L Q G+T G + + + Sbjct: 84 TPLIGVGACVSLQFG-----VNEAMKRFFHHRNADMSSTLSLPQYYACGVTGGIVNSFLA 138 Query: 464 SPADLALIRMQADS 505 SP + IR+Q + Sbjct: 139 SPIEHVRIRLQTQT 152 Score = 47.0 bits (110), Expect = 4e-05 Identities = 26/76 (34%), Positives = 39/76 (51%), Gaps = 7/76 (9%) Frame = +2 Query: 155 GGASGMLATCVIQPIDMIKVKIQLGE-------GSAAQVAKTMYANEGLGSFYKGLSAGL 313 G SG ++ P+D+IK +Q S + VAKT+YAN G+G+F+KG + Sbjct: 226 GALSGTALWLMVYPLDVIKSVMQTDNLQKPKFGNSISSVAKTLYANGGIGAFFKGFGPTM 285 Query: 314 LRQATYTTARLGSFRV 361 LR A A +F + Sbjct: 286 LRAAPANGATFATFEL 301
>GDC_MOUSE (Q8C0K5) Grave disease carrier protein homolog (GDC) (Mitochondrial| solute carrier protein homolog) (Solute carrier family 25 member 16) Length = 332 Score = 50.1 bits (118), Expect = 5e-06 Identities = 45/155 (29%), Positives = 69/155 (44%), Gaps = 20/155 (12%) Frame = +2 Query: 122 GVWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQL---GEGSAAQVA---KTMYANEG-- 277 GV + + G +GM A P+D+++V++ GE + + + KT+YA EG Sbjct: 126 GVSGHVHRLMAGSMAGMTAVICTYPLDVVRVRLAFQVKGEHTYSGIIHAFKTIYAKEGGF 185 Query: 278 LGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIE--------ANDGRPLPLVQKAFIGL 433 LG FY+GL +L A Y +F L + + + P LV K I L Sbjct: 186 LG-FYRGLMPTILGMAPYAGVSFFTFGTLKSVGLSYAPALLGRPSSDNPNVLVLKTHINL 244 Query: 434 ----TAGAIGACVGSPADLALIRMQADSTLPAAQR 526 AGAI + P D+ RMQ + LP ++ Sbjct: 245 LCGGVAGAIAQTISYPFDVTRRRMQLGAVLPEFEK 279 Score = 37.0 bits (84), Expect = 0.044 Identities = 34/158 (21%), Positives = 55/158 (34%), Gaps = 10/158 (6%) Frame = +2 Query: 137 IKPFVNGGASGMLATCVIQPIDMIKVKIQLGEG-----SAAQVAKTMYANEGLGSFYKGL 301 ++ F+ GG +G A + P+D +KV +Q + + EG YKG Sbjct: 37 LRSFLAGGIAGCCAKTTVAPLDRVKVLLQAHNRHYKHLGVLSTLRAVPQKEGYLGLYKGN 96 Query: 302 SAGLLRQATYTTARLGSFR-----VLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGS 466 A ++R Y + +F + T + + V + G AG Sbjct: 97 GAMMIRIFPYGAIQFMAFEHYKTFITTKLGVSGH-------VHRLMAGSMAGMTAVICTY 149 Query: 467 PADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEG 580 P D+ +R+ Y HA I A EG Sbjct: 150 PLDVVRVRL----AFQVKGEHTYSGIIHAFKTIYAKEG 183 Score = 29.3 bits (64), Expect = 9.1 Identities = 20/74 (27%), Positives = 34/74 (45%), Gaps = 9/74 (12%) Frame = +2 Query: 125 VWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQLGEG--------SAAQVAKTMYANEGL 280 V KT + GG +G +A + P D+ + ++QLG + + K +Y G+ Sbjct: 237 VLKTHINLLCGGVAGAIAQTISYPFDVTRRRMQLGAVLPEFEKCLTMRETMKYVYGQHGI 296 Query: 281 -GSFYKGLSAGLLR 319 Y+GLS +R Sbjct: 297 RRGLYRGLSLNYIR 310
>MPCP_BOVIN (P12234) Phosphate carrier protein, mitochondrial precursor (PTP)| (Solute carrier family 25 member 3) Length = 362 Score = 49.7 bits (117), Expect = 6e-06 Identities = 38/128 (29%), Positives = 55/128 (42%), Gaps = 11/128 (8%) Frame = +2 Query: 125 VWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSA---AQVAKTMYANEGLGSFYK 295 +W+T ++ A + P++ KV+IQ G A A MY EGL +FYK Sbjct: 159 LWRTSLYLAASASAEFFADIALAPMEAAKVRIQTQPGYANTLRDAAPKMYKEEGLKAFYK 218 Query: 296 GLSAGLLRQATYTTARLGSFRVLTNKAI--------EANDGRPLPLVQKAFIGLTAGAIG 451 G++ +RQ YT + F T +A+ + +P LV G AG Sbjct: 219 GVAPLWMRQIPYTMMKFACFE-RTVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFC 277 Query: 452 ACVGSPAD 475 A V PAD Sbjct: 278 AIVSHPAD 285
>MPCP_RAT (P16036) Phosphate carrier protein, mitochondrial precursor (PTP)| (Solute carrier family 25 member 3) Length = 356 Score = 49.7 bits (117), Expect = 6e-06 Identities = 41/160 (25%), Positives = 66/160 (41%), Gaps = 13/160 (8%) Frame = +2 Query: 119 TGVWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSA---AQVAKTMYANEGLGSF 289 T +W+T ++ A + P++ KV+IQ G A + MY EGL +F Sbjct: 151 TYLWRTSLYLAASASAEFFADIALAPMEAAKVRIQTQPGYANTLREAVPKMYKEEGLNAF 210 Query: 290 YKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKA-------FIGLTAGAI 448 YKG++ +RQ YT + F + +P KA G AG Sbjct: 211 YKGVAPVWMRQIPYTMMKFACFERTVEALYKFVVPKPRSECTKAEQLVVTFVAGYIAGVF 270 Query: 449 GACVGSPAD--LALIRMQADSTL-PAAQRRHYKNAFHALY 559 A V PAD ++++ + ST QR ++ + L+ Sbjct: 271 CAIVSHPADSVVSVLNKEKGSTASQVLQRLGFRGVWKGLF 310
>CMC1_PONPY (Q5RBC8) Calcium-binding mitochondrial carrier protein Aralar1| (Mitochondrial aspartate glutamate carrier 1) (Solute carrier family 25 member 12) Length = 678 Score = 49.3 bits (116), Expect = 8e-06 Identities = 45/191 (23%), Positives = 75/191 (39%), Gaps = 16/191 (8%) Frame = +2 Query: 74 PEEMADAKQQQAAA-PTGVWKTIKP----FVNGGASGMLATCVIQPIDMIKVKIQLGEGS 238 P +A+ ++QQ+ +W I F G +G + + PID++K ++Q GS Sbjct: 301 PYNLAELQRQQSPGLGRPIWLQIAESAYRFTLGSVAGAVGATAVYPIDLVKTRMQNQRGS 360 Query: 239 AAQVAKTMYAN-----------EGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEA 385 + V + MY N EG Y+GL L+ A +L + +K Sbjct: 361 GSVVGELMYKNSFDCFKKVLRYEGFFGLYRGLIPQLIGVAPEKAIKLTVNDFVRDKFTRR 420 Query: 386 NDGRPLPLVQKAFIGLTAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRI 565 + PLP + G AG +P ++ IR+Q + R N + Sbjct: 421 DGSVPLP--AEVLAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALN-------V 471 Query: 566 TADEGVLALWK 598 D G+ L+K Sbjct: 472 LRDLGIFGLYK 482
>CMC1_HUMAN (O75746) Calcium-binding mitochondrial carrier protein Aralar1| (Mitochondrial aspartate glutamate carrier 1) (Solute carrier family 25 member 12) Length = 678 Score = 49.3 bits (116), Expect = 8e-06 Identities = 45/191 (23%), Positives = 75/191 (39%), Gaps = 16/191 (8%) Frame = +2 Query: 74 PEEMADAKQQQAAA-PTGVWKTIKP----FVNGGASGMLATCVIQPIDMIKVKIQLGEGS 238 P +A+ ++QQ+ +W I F G +G + + PID++K ++Q GS Sbjct: 301 PYNLAELQRQQSPGLGRPIWLQIAESAYRFTLGSVAGAVGATAVYPIDLVKTRMQNQRGS 360 Query: 239 AAQVAKTMYAN-----------EGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEA 385 + V + MY N EG Y+GL L+ A +L + +K Sbjct: 361 GSVVGELMYKNSFDCFKKVLRYEGFFGLYRGLIPQLIGVAPEKAIKLTVNDFVRDKFTRR 420 Query: 386 NDGRPLPLVQKAFIGLTAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRI 565 + PLP + G AG +P ++ IR+Q + R N + Sbjct: 421 DGSVPLP--AEVLAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALN-------V 471 Query: 566 TADEGVLALWK 598 D G+ L+K Sbjct: 472 LRDLGIFGLYK 482
>GDC_HUMAN (P16260) Grave disease carrier protein (GDC) (Grave disease| autoantigen) (GDA) (Mitochondrial solute carrier protein homolog) (Solute carrier family 25 member 16) Length = 332 Score = 48.5 bits (114), Expect = 1e-05 Identities = 41/154 (26%), Positives = 64/154 (41%), Gaps = 19/154 (12%) Frame = +2 Query: 122 GVWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQL---GEGSAAQVA---KTMYANE-GL 280 G+ + + G +GM A P+DM++V++ GE + KT+YA E G Sbjct: 126 GISGHVHRLMAGSMAGMTAVICTDPVDMVRVRLAFQVKGEHRYTGIIHAFKTIYAKEGGF 185 Query: 281 GSFYKGLSAGLLRQATYTTARLGSFRVLTNKAI--------EANDGRPLPLVQKAFIGLT 436 FY+GL +L A Y +F L + + + P LV K + L Sbjct: 186 FGFYRGLMPTILGMAPYAGVSFFTFGTLKSVGLSHAPTLLGSPSSDNPNVLVLKTHVNLL 245 Query: 437 AG----AIGACVGSPADLALIRMQADSTLPAAQR 526 G AI + P D+ RMQ + LP ++ Sbjct: 246 CGGVARAIAQTISYPFDVTRRRMQLGTVLPEFEK 279 Score = 38.1 bits (87), Expect = 0.020 Identities = 38/161 (23%), Positives = 58/161 (36%), Gaps = 13/161 (8%) Frame = +2 Query: 137 IKPFVNGGASGMLATCVIQPIDMIKVKIQ--------LGEGSAAQVAKTMYANEGLGSFY 292 ++ F+ G +G A + P+D +KV +Q LG SA + + EG Y Sbjct: 37 LRSFLAGSIAGCCAKTTVAPLDRVKVLLQAHNHHYKHLGVFSA---LRAVPQKEGFLGLY 93 Query: 293 KGLSAGLLRQATYTTARLGSFR-----VLTNKAIEANDGRPLPLVQKAFIGLTAGAIGAC 457 KG A ++R Y + +F + T I + V + G AG Sbjct: 94 KGNGAMMIRIFPYGAIQFMAFEHYKTLITTKLGISGH-------VHRLMAGSMAGMTAVI 146 Query: 458 VGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEG 580 P D+ +R+ Y HA I A EG Sbjct: 147 CTDPVDMVRVRL----AFQVKGEHRYTGIIHAFKTIYAKEG 183
>MFTC_MOUSE (Q8BMG8) Mitochondrial folate transporter/carrier (Solute carrier| family 25 member 32) Length = 316 Score = 48.1 bits (113), Expect = 2e-05 Identities = 39/182 (21%), Positives = 77/182 (42%), Gaps = 15/182 (8%) Frame = +2 Query: 98 QQQAAAPTGVWKTI------KPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQ---- 247 Q Q+AA + W + + V G + G+L+ + P+D++K++ + +G + Sbjct: 4 QGQSAAGSAAWSAVFRHVRYENLVAGVSGGVLSNLALHPLDLVKIRFAVSDGLEVRPKYK 63 Query: 248 ----VAKTMYANEGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQ 415 T++ +GL Y+G++ + + + + E + PL + Sbjct: 64 GILHCLATIWKVDGLRGLYQGVTPNVWGAGLSWGLYFFFYNAIKSYKTEGRAEQLEPL-E 122 Query: 416 KAFIGLTAGAIGACVGSPADLALIRMQAD-STLPAAQRRHYKNAFHALYRITADEGVLAL 592 AGA+ C+ +P + R+ + + +R YK F AL +I EGV L Sbjct: 123 YLVSAAEAGAMTLCITNPLWVTKTRLMLQYGGVASPSQRQYKGMFDALVKIYKYEGVRGL 182 Query: 593 WK 598 +K Sbjct: 183 YK 184 Score = 33.1 bits (74), Expect = 0.63 Identities = 15/55 (27%), Positives = 27/55 (49%), Gaps = 3/55 (5%) Frame = +2 Query: 164 SGMLATCVIQPIDMIKVKIQ---LGEGSAAQVAKTMYANEGLGSFYKGLSAGLLR 319 S + A P +++ ++Q + G V + EG+G FYKG++ L+R Sbjct: 234 SKIFAVAATYPYQVVRARLQDQHVSYGGVTDVITKTWRKEGIGGFYKGIAPNLIR 288
>RIM2_YEAST (P38127) Mitochondrial carrier protein RIM2| Length = 377 Score = 48.1 bits (113), Expect = 2e-05 Identities = 49/193 (25%), Positives = 75/193 (38%), Gaps = 38/193 (19%) Frame = +2 Query: 134 TIKP---FVNGGASGMLATCVIQPIDMIKVKIQLG------EGSAAQVAK---------- 256 T+KP FV GG GM V P D++K ++Q + A ++K Sbjct: 49 TVKPWVHFVAGGIGGMAGAVVTCPFDLVKTRLQSDIFLKAYKSQAVNISKGSTRPKSINY 108 Query: 257 ----------------TMYANEGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEA- 385 +Y EG S +KGL L+ + F T K + A Sbjct: 109 VIQAGTHFKETLGIIGNVYKQEGFRSLFKGLGPNLV--GVIPARSINFFTYGTTKDMYAK 166 Query: 386 --NDGRPLPLVQKAFIGLTAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALY 559 N+G+ P++ TAG A +P L R+Q D + R+ YKN++ L Sbjct: 167 AFNNGQETPMIH-LMAAATAGWATATATNPIWLIKTRVQLDKAGKTSVRQ-YKNSWDCLK 224 Query: 560 RITADEGVLALWK 598 + +EG L+K Sbjct: 225 SVIRNEGFTGLYK 237 Score = 31.6 bits (70), Expect = 1.8 Identities = 19/60 (31%), Positives = 26/60 (43%), Gaps = 9/60 (15%) Frame = +2 Query: 164 SGMLATCVIQPIDMIKVKIQLGEGSAAQVA---------KTMYANEGLGSFYKGLSAGLL 316 +G PI +IK ++QL + V K++ NEG YKGLSA L Sbjct: 185 AGWATATATNPIWLIKTRVQLDKAGKTSVRQYKNSWDCLKSVIRNEGFTGLYKGLSASYL 244
>TXTP_BOVIN (P79110) Tricarboxylate transport protein, mitochondrial precursor| (Citrate transport protein) (CTP) (Tricarboxylate carrier protein) (Solute carrier family 25 member 1) Length = 311 Score = 47.8 bits (112), Expect = 2e-05 Identities = 41/156 (26%), Positives = 67/156 (42%), Gaps = 8/156 (5%) Frame = +2 Query: 140 KPFVNGGASGMLATCVIQPIDMIKVKIQLGEGS-------AAQVAKTMYANEGLGSFYKG 298 K + GG +G + C+ P + +K ++QL E S + + GL Y+G Sbjct: 27 KAILAGGLAGGIEICITFPTEYVKTQLQLDERSHPPRYRGIGDCVRQTVRSHGLLGLYRG 86 Query: 299 LSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGA-CVGSPAD 475 LS+ L R G+F L+N +A GR L + GL AG A V P + Sbjct: 87 LSSLLYGSIPKAAVRFGTFEFLSNHMRDA-QGR-LDSTRGLLCGLGAGVPEAVVVVCPME 144 Query: 476 LALIRMQADSTLPAAQRRHYKNAFHALYRITADEGV 583 ++ D T + + Y+ FH + I ++G+ Sbjct: 145 TIKVKFIHDQTSASPK---YRGFFHGVREIVREQGL 177 Score = 46.6 bits (109), Expect = 5e-05 Identities = 43/155 (27%), Positives = 67/155 (43%), Gaps = 8/155 (5%) Frame = +2 Query: 158 GASGMLATCVIQPIDMIKVKIQLGEGSAAQVAKTMY-------ANEGLGSFYKGLSAGLL 316 GA A V+ P++ IKVK + SA+ + + +GL Y+GL+A +L Sbjct: 130 GAGVPEAVVVVCPMETIKVKFIHDQTSASPKYRGFFHGVREIVREQGLKGTYQGLTATVL 189 Query: 317 RQATYTTARLGSFRVLTNKAIEANDGRPL-PLVQKAFIGLTAGAIGACVGSPADLALIRM 493 +Q + R L N N +P+ PL+ F G AGA +P D+ RM Sbjct: 190 KQGSNQGIRFFVMTSLRNWYRGDNPNKPMNPLITGVF-GAIAGAASVFGNTPLDVIKTRM 248 Query: 494 QADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 Q + Y+N +I +EG+ A +K Sbjct: 249 Q------GLEAHKYRNTLDCGLQILRNEGLKAFYK 277
>MPCP_CAEEL (P40614) Phosphate carrier protein, mitochondrial precursor (PTP)| Length = 340 Score = 47.8 bits (112), Expect = 2e-05 Identities = 37/141 (26%), Positives = 57/141 (40%), Gaps = 10/141 (7%) Frame = +2 Query: 125 VWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQV---AKTMYANEGLGSFYK 295 +++T ++ A ++ P++ KV+IQ G+ + A +Y EGL FYK Sbjct: 137 LYRTSLYLAASASAEFFADILLAPMEATKVRIQTSPGAPPTLRGCAPMIYKAEGLTGFYK 196 Query: 296 GLSAGLLRQATYTTARLGSFRVLTNKAIE-------ANDGRPLPLVQKAFIGLTAGAIGA 454 GL +RQ YT + F + A + LV G AG A Sbjct: 197 GLPPLWMRQIPYTMMKFACFEKTVEALYQYVVPKPRAECSKAEQLVVTFVAGYIAGVFCA 256 Query: 455 CVGSPADLALIRMQADSTLPA 517 V PAD + ++ DS A Sbjct: 257 IVSHPADTVVSKLNQDSQATA 277
>MFTC_HUMAN (Q9H2D1) Mitochondrial folate transporter/carrier (Solute carrier| family 25 member 32) Length = 315 Score = 47.4 bits (111), Expect = 3e-05 Identities = 39/183 (21%), Positives = 78/183 (42%), Gaps = 16/183 (8%) Frame = +2 Query: 98 QQQAAAPTGVWKTI------KPFVNGGASGMLATCVIQPIDMIKVKIQLGEG-------- 235 Q Q+A+ + W T+ + + G + G+L+ + P+D++K++ + +G Sbjct: 4 QGQSASGSSAWSTVFRHVRYENLIAGVSGGVLSNLALHPLDLVKIRFAVSDGLELRPKYN 63 Query: 236 SAAQVAKTMYANEGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQ 415 T++ +GL Y+G++ + + + + E R L + Sbjct: 64 GILHCLTTIWKLDGLRGLYQGVTPNIWGAGLSWGLYFFFYNAIKSYKTEGRAER-LEATE 122 Query: 416 KAFIGLTAGAIGACVGSPADLALIRM--QADSTLPAAQRRHYKNAFHALYRITADEGVLA 589 AGA+ C+ +P + R+ Q D+ + + R+ YK F L +I EGV Sbjct: 123 YLVSAAEAGAMTLCITNPLWVTKTRLMLQYDAVVNSPHRQ-YKGMFDTLVKIYKYEGVRG 181 Query: 590 LWK 598 L+K Sbjct: 182 LYK 184 Score = 30.0 bits (66), Expect = 5.3 Identities = 18/72 (25%), Positives = 32/72 (44%), Gaps = 4/72 (5%) Frame = +2 Query: 116 PTGVWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQ----LGEGSAAQVAKTMYANEGLG 283 P T++ S + A P +++ ++Q G + KT + EG+G Sbjct: 218 PEAQLSTVEYISVAALSKIFAVAATYPYQVVRARLQDQHMFYSGVIDVITKT-WRKEGVG 276 Query: 284 SFYKGLSAGLLR 319 FYKG++ L+R Sbjct: 277 GFYKGIAPNLIR 288
>AGC1_ASHGO (Q75AH6) Mitochondrial aspartate-glutamate transporter AGC1| (Aspartate-glutamate carrier 1) Length = 911 Score = 47.4 bits (111), Expect = 3e-05 Identities = 39/163 (23%), Positives = 70/163 (42%), Gaps = 5/163 (3%) Frame = +2 Query: 125 VWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQLGEG-----SAAQVAKTMYANEGLGSF 289 ++ +I F G +G + V+ PIDM+K ++Q ++ + + EG+ Sbjct: 520 IFDSIYNFTLGSVAGCIGAMVVYPIDMVKTRMQAQRDFSKYKNSIDCLLKILSKEGVRGL 579 Query: 290 YKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSP 469 Y GL L+ A +L + + DG+ L L + G TAGA +P Sbjct: 580 YSGLGPQLIGVAPEKAIKL-TVNDHMRATLAGRDGK-LSLPCEIISGATAGACQVVFTNP 637 Query: 470 ADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 ++ IR+Q S A R+ NA + + G++ L++ Sbjct: 638 LEIVKIRLQVKSDYVADAARNSVNAISVIKNL----GLIGLYR 676 Score = 44.3 bits (103), Expect = 3e-04 Identities = 28/101 (27%), Positives = 46/101 (45%), Gaps = 7/101 (6%) Frame = +2 Query: 89 DAKQQQAAAPTGVWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQV------ 250 D K W+ + V+GG +GM A + P D+IK ++Q+ V Sbjct: 707 DPKDSDKRNKLNTWQLL---VSGGLAGMPAAFLTTPFDVIKTRLQIDPKKGESVYNGIWD 763 Query: 251 -AKTMYANEGLGSFYKGLSAGLLRQATYTTARLGSFRVLTN 370 A+T+ EG+ SF+KG A +LR + L ++ + N Sbjct: 764 AARTILKEEGIKSFFKGGPARVLRSSPQFGFTLAAYEIFHN 804
>CMC1_MOUSE (Q8BH59) Calcium-binding mitochondrial carrier protein Aralar1| (Mitochondrial aspartate glutamate carrier 1) (Solute carrier family 25 member 12) Length = 677 Score = 47.4 bits (111), Expect = 3e-05 Identities = 44/191 (23%), Positives = 76/191 (39%), Gaps = 16/191 (8%) Frame = +2 Query: 74 PEEMADAKQQQAAA-PTGVWKTIKP----FVNGGASGMLATCVIQPIDMIKVKIQLGEGS 238 P +A+ ++QQ+ +W I F G +G + + PID++K ++Q G+ Sbjct: 301 PYNLAELQRQQSPGLGRPIWLQIAESAYRFTLGSVAGAVGATAVYPIDLVKTRMQNQRGT 360 Query: 239 AAQVAKTMYAN-----------EGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEA 385 + V + MY N EG Y+GL L+ A +L + +K + Sbjct: 361 GSVVGELMYKNSFDCFKKVLRYEGFFGLYRGLIPQLIGVAPEKAIKLTVNDFVRDKFTKR 420 Query: 386 NDGRPLPLVQKAFIGLTAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRI 565 + PLP + G AG +P ++ IR+Q + R N + Sbjct: 421 DGSIPLP--AEILAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALN-------V 471 Query: 566 TADEGVLALWK 598 D G+ L+K Sbjct: 472 LQDLGLFGLYK 482
>CMC3_CAEEL (Q19529) Probable calcium-binding mitochondrial carrier F17E5.2| Length = 531 Score = 47.0 bits (110), Expect = 4e-05 Identities = 36/165 (21%), Positives = 70/165 (42%), Gaps = 5/165 (3%) Frame = +2 Query: 119 TGVWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQV-----AKTMYANEGLG 283 +GVW + V GG +G ++ P D IKV +Q+ ++ ++A G+ Sbjct: 241 SGVWW--RHLVAGGVAGAMSRTCTAPFDRIKVYLQVNSTKTNKLGVVSCVHLLHAEGGIK 298 Query: 284 SFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVG 463 SF++G +++ A + + + + E G L +++ G +AGAI Sbjct: 299 SFWRGNGINVIKIAPESAMKFMCYDQIKRWMQEYKGGAELSTIERLLAGSSAGAISQTAI 358 Query: 464 SPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 P ++ R+ T + K FH +++ EG+ +K Sbjct: 359 YPMEVMKTRLALRRT-----GQLDKGMFHFAHKMYTKEGIKCFYK 398 Score = 37.7 bits (86), Expect = 0.026 Identities = 40/161 (24%), Positives = 64/161 (39%), Gaps = 18/161 (11%) Frame = +2 Query: 134 TIKPFVNGGASGMLATCVIQPIDMIKVKI------QLGEGSAAQVAKTMYANEGLGSFYK 295 TI+ + G ++G ++ I P++++K ++ QL +G A MY EG+ FYK Sbjct: 340 TIERLLAGSSAGAISQTAIYPMEVMKTRLALRRTGQLDKGMF-HFAHKMYTKEGIKCFYK 398 Query: 296 GLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLP-LVQKAFIGLTAGAIGACVGSPA 472 G LL Y L + L + + P ++ G + G P Sbjct: 399 GYLPNLLGIIPYAGIDLTVYESLKSMYTKYYTEHTEPGVLALLACGTCSSTCGQLASYPL 458 Query: 473 DLALIRMQA------DSTLPAAQRRHYKN-----AFHALYR 562 L R+QA +ST P +K+ F LYR Sbjct: 459 ALVRTRLQARAISPKNSTQPDTMVGQFKHILQTEGFTGLYR 499
>MCAT_ARATH (Q93XM7) Mitochondrial carnitine/acylcarnitine carrier-like protein| (Protein A BOUT DE SOUFFLE) (Carnitine/acylcarnitine translocase-like protein) (CAC-like protein) Length = 300 Score = 46.6 bits (109), Expect = 5e-05 Identities = 41/141 (29%), Positives = 58/141 (41%), Gaps = 10/141 (7%) Frame = +2 Query: 128 WKTIKPFVNGGASGMLATCVIQPIDMIKVKIQLGEG----------SAAQVAKTMYANEG 277 WK + GGA+ ++ V P D IKVK+Q A K A+EG Sbjct: 5 WKDLASGTVGGAAQLV---VGHPFDTIKVKLQSQPTPAPGQLPRYTGAIDAVKQTVASEG 61 Query: 278 LGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGAC 457 YKG+ A L A + A L + R + + G PL + Q+ G AG + Sbjct: 62 TKGLYKGMGAPLATVAAF-NAVLFTVRGQMEGLLRSEAGVPLTISQQFVAGAGAGFAVSF 120 Query: 458 VGSPADLALIRMQADSTLPAA 520 + P +L R+QA L A Sbjct: 121 LACPTELIKCRLQAQGALAGA 141
>DIF1_CAEEL (Q27257) Protein dif-1| Length = 312 Score = 46.2 bits (108), Expect = 7e-05 Identities = 42/158 (26%), Positives = 63/158 (39%), Gaps = 10/158 (6%) Frame = +2 Query: 155 GGASGMLATCVIQPIDMIKVKIQLGEGSAA----------QVAKTMYANEGLGSFYKGLS 304 G +G+ T V+ P + IK +Q+ + +A V K +Y G+ S Y+G Sbjct: 111 GALAGVFTTIVMVPGERIKCLLQVQQAGSAGSGVHYDGPLDVVKKLYKQGGISSIYRGTG 170 Query: 305 AGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLAL 484 A LLR + A L + L K R L G AG V PAD+ Sbjct: 171 ATLLRDIPASAAYLSVYEYLKKKFSGEGAQRTLSPGATLMAGGLAGIANWGVCIPADVLK 230 Query: 485 IRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 R+Q A + ++ L + +EG AL+K Sbjct: 231 SRLQT-----APEGKYPDGIRGVLREVLREEGPRALFK 263 Score = 44.3 bits (103), Expect = 3e-04 Identities = 38/162 (23%), Positives = 62/162 (38%), Gaps = 11/162 (6%) Frame = +2 Query: 146 FVNGGASGMLATCVIQPIDMIKVKIQL------GE----GSAAQVAKTMYANEGLGSFYK 295 F+ GG G V P D +KV+IQ GE A K + EG + YK Sbjct: 8 FIAGGVGGSCTVIVGHPFDTVKVRIQTMPMPKPGEKPQFTGALDCVKRTVSKEGFFALYK 67 Query: 296 GLSAGLLRQATYTTARLGSFRVLTNKAIEAND-GRPLPLVQKAFIGLTAGAIGACVGSPA 472 G++A L+ + G V K ++ D + + +Q A G AG V P Sbjct: 68 GMAAPLVGVSPLFAVFFGGCAV--GKWLQQTDPSQEMTFIQNANAGALAGVFTTIVMVPG 125 Query: 473 DLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 + +Q A HY + ++ G+ ++++ Sbjct: 126 ERIKCLLQVQQAGSAGSGVHYDGPLDVVKKLYKQGGISSIYR 167
>CMC2_HUMAN (Q9UJS0) Calcium-binding mitochondrial carrier protein Aralar2| (Mitochondrial aspartate glutamate carrier 2) (Solute carrier family 25 member 13) (Citrin) Length = 675 Score = 45.8 bits (107), Expect = 9e-05 Identities = 39/151 (25%), Positives = 64/151 (42%), Gaps = 3/151 (1%) Frame = +2 Query: 155 GGASGMLATCVIQPIDMIKVKIQL-GEGSAAQVAKTMYANEGLGSF--YKGLSAGLLRQA 325 GG +G P++++K+++Q+ GE + + LG F YKG A LR Sbjct: 435 GGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALSVVRDLGFFGIYKGAKACFLRDI 494 Query: 326 TYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLALIRMQADS 505 ++ + + KA AN+ + G AG A + +PAD+ R+Q + Sbjct: 495 PFSAIYFPCYAHV--KASFANEDGQVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQVAA 552 Query: 506 TLPAAQRRHYKNAFHALYRITADEGVLALWK 598 A + Y +I +EG ALWK Sbjct: 553 R---AGQTTYSGVIDCFRKILREEGPKALWK 580 Score = 45.1 bits (105), Expect = 2e-04 Identities = 40/168 (23%), Positives = 71/168 (42%), Gaps = 17/168 (10%) Frame = +2 Query: 74 PEEMADAKQQQAAAPTG------VWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQLGEG 235 P +A+A++Q+A+ + V ++ F G +G + + PID++K ++Q Sbjct: 302 PFNLAEAQRQKASGDSARPVLLQVAESAYRFGLGSVAGAVGATAVYPIDLVKTRMQNQRS 361 Query: 236 SAAQVAKTMYAN-----------EGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIE 382 + + V + MY N EG Y+GL LL A +L + +K + Sbjct: 362 TGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKFMH 421 Query: 383 ANDGRPLPLVQKAFIGLTAGAIGACVGSPADLALIRMQADSTLPAAQR 526 DG +PL + G AG +P ++ IR+Q + R Sbjct: 422 -KDG-SVPLAAEILAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPR 467 Score = 30.4 bits (67), Expect = 4.1 Identities = 21/81 (25%), Positives = 38/81 (46%), Gaps = 11/81 (13%) Frame = +2 Query: 155 GGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAKTMYA-----------NEGLGSFYKGL 301 G +GM A ++ P D+IK ++Q+ AA+ +T Y+ EG + +KG Sbjct: 527 GAIAGMPAASLVTPADVIKTRLQV----AARAGQTTYSGVIDCFRKILREEGPKALWKGA 582 Query: 302 SAGLLRQATYTTARLGSFRVL 364 A + R + L ++ +L Sbjct: 583 GARVFRSSPQFGVTLLTYELL 603
>CMC2_MOUSE (Q9QXX4) Calcium-binding mitochondrial carrier protein Aralar2| (Mitochondrial aspartate glutamate carrier 2) (Solute carrier family 25 member 13) (Citrin) Length = 676 Score = 45.8 bits (107), Expect = 9e-05 Identities = 41/169 (24%), Positives = 72/169 (42%), Gaps = 18/169 (10%) Frame = +2 Query: 74 PEEMADAKQQQAAAPTG-------VWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQLGE 232 P +A+A++QQ A+ + ++ F G +G + + PID++K ++Q Sbjct: 302 PFNLAEAQRQQKASGDAARPFLLQLAESAYRFGLGSIAGAVGATAVYPIDLVKTRMQNQR 361 Query: 233 GSAAQVAKTMYAN-----------EGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAI 379 + + V + MY N EG Y+GL LL A +L + +K + Sbjct: 362 STGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKFM 421 Query: 380 EANDGRPLPLVQKAFIGLTAGAIGACVGSPADLALIRMQADSTLPAAQR 526 DG +PL+ + F G AG +P ++ IR+Q + R Sbjct: 422 H-KDG-SVPLLAEIFAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPR 468 Score = 30.8 bits (68), Expect = 3.1 Identities = 21/81 (25%), Positives = 39/81 (48%), Gaps = 11/81 (13%) Frame = +2 Query: 155 GGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAKTMY-----------ANEGLGSFYKGL 301 G +GM A ++ P D+IK ++Q+ AA+ +T Y EG + +KG+ Sbjct: 528 GAIAGMPAASLVTPADVIKTRLQV----AARAGQTTYNGVTDCFRKILREEGPKALWKGV 583 Query: 302 SAGLLRQATYTTARLGSFRVL 364 +A + R + L ++ +L Sbjct: 584 AARVFRSSPQFGVTLLTYELL 604
>LEU5_YEAST (P38702) Mitochondrial carrier protein LEU5| Length = 357 Score = 45.8 bits (107), Expect = 9e-05 Identities = 34/123 (27%), Positives = 55/123 (44%), Gaps = 10/123 (8%) Frame = +2 Query: 155 GGASGMLATCVIQPIDMIKVKIQLGE-------GSA---AQVAKTMYANEGLGSFYKGLS 304 GG SG A +I P+D IK+ Q GS + AK ++ N+G+ F++G S Sbjct: 40 GGISGSCAKTLIAPLDRIKILFQTSNPHYTKYTGSLIGLVEAAKHIWINDGVRGFFQGHS 99 Query: 305 AGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLAL 484 A LLR Y + ++ + N I + + ++ G AG + P DL Sbjct: 100 ATLLRIFPYAAVKFVAYEQIRNTLIPSKEFE--SHWRRLVSGSLAGLCSVFITYPLDLVR 157 Query: 485 IRM 493 +R+ Sbjct: 158 VRL 160 Score = 35.0 bits (79), Expect = 0.17 Identities = 19/95 (20%), Positives = 45/95 (47%), Gaps = 11/95 (11%) Frame = +2 Query: 68 ISPEEMADAKQQQAAAPTGVWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQLGE----- 232 +S ++ + Q++ P W + ++GG +GM + P ++I+ ++Q+ Sbjct: 245 LSEDDELERVQKKQRRPLRTWAEL---ISGGLAGMASQTAAYPFEIIRRRLQVSALSPKT 301 Query: 233 ------GSAAQVAKTMYANEGLGSFYKGLSAGLLR 319 S +++A ++ G+ F+ GLS G ++ Sbjct: 302 MYDHKFQSISEIAHIIFKERGVRGFFVGLSIGYIK 336
>MFTC_MACFA (Q95J75) Mitochondrial folate transporter/carrier (Solute carrier| family 25 member 32) Length = 315 Score = 45.8 bits (107), Expect = 9e-05 Identities = 39/183 (21%), Positives = 77/183 (42%), Gaps = 16/183 (8%) Frame = +2 Query: 98 QQQAAAPTGVWKTI------KPFVNGGASGMLATCVIQPIDMIKVKIQLGEG-------- 235 Q +A+ + W T+ + V G + G+L+ + P+D++K++ + +G Sbjct: 4 QGHSASGSSAWSTVFRHVRYENLVAGVSGGVLSNLALHPLDLVKIRFAVSDGLELRPKYN 63 Query: 236 SAAQVAKTMYANEGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQ 415 T++ +GL Y+G++ + + + + E R L + Sbjct: 64 GILHCLTTIWKLDGLRGLYQGVTPNVWGAGLSWGLYFFFYNAIKSYKTEGRAER-LEATE 122 Query: 416 KAFIGLTAGAIGACVGSPADLALIRM--QADSTLPAAQRRHYKNAFHALYRITADEGVLA 589 AGA+ C+ +P + R+ Q D+ + + R+ YK F L +I EGV Sbjct: 123 YLVSAAEAGAMTLCITNPLWVTKTRLMLQYDAVINSPHRQ-YKGMFDTLVKIYKYEGVRG 181 Query: 590 LWK 598 L+K Sbjct: 182 LYK 184 Score = 30.4 bits (67), Expect = 4.1 Identities = 18/72 (25%), Positives = 32/72 (44%), Gaps = 4/72 (5%) Frame = +2 Query: 116 PTGVWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQ----LGEGSAAQVAKTMYANEGLG 283 P T++ S + A P +++ ++Q G + KT + EG+G Sbjct: 218 PEAQLSTVEYISVAALSKIFAVAATYPYQVVRARLQDQHMFYSGVIDVITKT-WRKEGIG 276 Query: 284 SFYKGLSAGLLR 319 FYKG++ L+R Sbjct: 277 GFYKGIAPNLIR 288
>GDC_RAT (P16261) Grave disease carrier protein (GDC) (Mitochondrial solute| carrier protein homolog) (Solute carrier family 25 member 16) (Fragment) Length = 322 Score = 45.4 bits (106), Expect = 1e-04 Identities = 41/143 (28%), Positives = 63/143 (44%), Gaps = 20/143 (13%) Frame = +2 Query: 158 GASGMLATCVIQPIDMIKVKIQL---GEGSAAQVA---KTMYANEG--LGSFYKGLSAGL 313 G M A P+D+++V++ GE + + + KT+YA EG LG FY+GL + Sbjct: 141 GKMSMTAVICTYPLDVVRVRLAFQVKGEHTYSGIIHAFKTIYAKEGGFLG-FYRGLMPTI 199 Query: 314 LRQATYTTARLGSFRVLTNKAI--------EANDGRPLPLVQKAFIGLTAG----AIGAC 457 L A Y + +F L + + + P LV K I L G AI Sbjct: 200 LGMAPYASVSFFTFGTLKSVGLSYAPTLLGRPSSDNPNVLVLKTHINLLCGGVARAIAQT 259 Query: 458 VGSPADLALIRMQADSTLPAAQR 526 + P D+ RMQ + LP ++ Sbjct: 260 ISYPFDVTRRRMQLGAVLPEFEK 282 Score = 29.6 bits (65), Expect = 6.9 Identities = 33/161 (20%), Positives = 56/161 (34%), Gaps = 13/161 (8%) Frame = +2 Query: 137 IKPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVA-----KTMYANEGLGSFYKGL 301 ++ F+ G +G A + P+D +KV +Q + + + EG YKG Sbjct: 37 LRSFLAGSIAGCCAKTTVAPLDRVKVLLQAHNHHYKHLGVLSPLRAVPQKEGYLGLYKGN 96 Query: 302 SAGLLRQATYTTARLGSFR-----VLTNKAIEANDGRPLPLVQKAFIGLTAGAI---GAC 457 A ++R Y + +F + T + + V + G AG + Sbjct: 97 GAMMIRIFPYGAIQFMAFEHYKTFITTKLGVSGH-------VHRLMAGSMAGKMSMTAVI 149 Query: 458 VGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEG 580 P D+ +R+ Y HA I A EG Sbjct: 150 CTYPLDVVRVRL----AFQVKGEHTYSGIIHAFKTIYAKEG 186
>CMC2_MACFA (Q8HXW2) Calcium-binding mitochondrial carrier protein Aralar2| (Mitochondrial aspartate glutamate carrier 2) (Solute carrier family 25 member 13) (Citrin) Length = 674 Score = 45.1 bits (105), Expect = 2e-04 Identities = 40/168 (23%), Positives = 71/168 (42%), Gaps = 17/168 (10%) Frame = +2 Query: 74 PEEMADAKQQQAAAPTG------VWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQLGEG 235 P +A+A++Q+A+ + V ++ F G +G + + PID++K ++Q Sbjct: 302 PFNLAEAQRQKASGDSARPVLLQVAESAYRFGLGSVAGAVGATAVYPIDLVKTRMQNQRS 361 Query: 236 SAAQVAKTMYAN-----------EGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIE 382 + + V + MY N EG Y+GL LL A +L + +K + Sbjct: 362 TGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKFMH 421 Query: 383 ANDGRPLPLVQKAFIGLTAGAIGACVGSPADLALIRMQADSTLPAAQR 526 DG +PL + G AG +P ++ IR+Q + R Sbjct: 422 -KDG-SVPLAAEILAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPR 467 Score = 43.9 bits (102), Expect = 4e-04 Identities = 38/151 (25%), Positives = 63/151 (41%), Gaps = 3/151 (1%) Frame = +2 Query: 155 GGASGMLATCVIQPIDMIKVKIQL-GEGSAAQVAKTMYANEGLGSF--YKGLSAGLLRQA 325 GG +G P++++K+++Q+ GE + + LG F YKG A LR Sbjct: 435 GGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALSVVRDLGFFGIYKGAKACFLRDI 494 Query: 326 TYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLALIRMQADS 505 ++ + +A AN+ + G AG A + +PAD+ R+Q + Sbjct: 495 PFSAIYFPCYAHA--RASFANEDGQVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQVAA 552 Query: 506 TLPAAQRRHYKNAFHALYRITADEGVLALWK 598 A + Y +I +EG ALWK Sbjct: 553 R---AGQTTYSGVIDCFKKILREEGPKALWK 580
>AGC1_YEAST (Q12482) Mitochondrial aspartate-glutamate transporter AGC1| (Aspartate-glutamate carrier 1) Length = 902 Score = 44.7 bits (104), Expect = 2e-04 Identities = 34/133 (25%), Positives = 59/133 (44%), Gaps = 6/133 (4%) Frame = +2 Query: 125 VWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAKTM------YANEGLGS 286 ++ ++ F G +G + V+ PID IK ++Q + S AQ ++ + EG+ Sbjct: 527 IFDSLYNFSLGSIAGCIGATVVYPIDFIKTRMQ-AQRSLAQYKNSIDCLLKIISREGIKG 585 Query: 287 FYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGS 466 Y GL L+ A +L + N+ + N L L + G +AGA + Sbjct: 586 LYSGLGPQLIGVAPEKAIKLTVNDFMRNRLTDKNG--KLSLFPEIISGASAGACQVIFTN 643 Query: 467 PADLALIRMQADS 505 P ++ IR+Q S Sbjct: 644 PLEIVKIRLQVQS 656 Score = 37.0 bits (84), Expect = 0.044 Identities = 22/57 (38%), Positives = 29/57 (50%) Frame = +2 Query: 425 IGLTAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALW 595 +G AG IGA V P D RMQA +L YKN+ L +I + EG+ L+ Sbjct: 536 LGSIAGCIGATVVYPIDFIKTRMQAQRSL-----AQYKNSIDCLLKIISREGIKGLY 587 Score = 32.3 bits (72), Expect = 1.1 Identities = 22/72 (30%), Positives = 34/72 (47%), Gaps = 7/72 (9%) Frame = +2 Query: 131 KTIKPFVNGGASGMLATCVIQPIDMIKVKIQL----GE---GSAAQVAKTMYANEGLGSF 289 KT + G +GM A + P D+IK ++Q+ GE +T+ E SF Sbjct: 726 KTWELLTAGAIAGMPAAFLTTPFDVIKTRLQIDPRKGETKYNGIFHAIRTILKEESFRSF 785 Query: 290 YKGLSAGLLRQA 325 +KG A +LR + Sbjct: 786 FKGGGARVLRSS 797
>ORT1_YEAST (Q12375) Mitochondrial ornithine carrier protein| Length = 292 Score = 44.7 bits (104), Expect = 2e-04 Identities = 35/159 (22%), Positives = 67/159 (42%), Gaps = 5/159 (3%) Frame = +2 Query: 137 IKPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVA----KTMYANEGLG-SFYKGL 301 I +NG +G + P D +KV++Q + K Y NEG+ F++G+ Sbjct: 14 ILDIINGSIAGACGKVIEFPFDTVKVRLQTQASNVFPTTWSCIKFTYQNEGIARGFFQGI 73 Query: 302 SAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLA 481 ++ L+ S+ +K +E + PL Q G AG+ + V +P +L Sbjct: 74 ASPLVGACLENATLFVSYN-QCSKFLEKHT-NVFPLGQILISGGVAGSCASLVLTPVELV 131 Query: 482 LIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 ++Q + A+ + + + I + G+ LW+ Sbjct: 132 KCKLQVANLQVASAKTKHTKVLPTIKAIITERGLAGLWQ 170 Score = 38.5 bits (88), Expect = 0.015 Identities = 22/81 (27%), Positives = 36/81 (44%) Frame = +2 Query: 125 VWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAKTMYANEGLGSFYKGLS 304 +W+ + ++GG++G+ I P D +K +Q S K ++ GL FY+GL Sbjct: 213 IWELL---ISGGSAGLAFNASIFPADTVKSVMQTEHISLTNAVKKIFGKFGLKGFYRGLG 269 Query: 305 AGLLRQATYTTARLGSFRVLT 367 L R A F L+ Sbjct: 270 ITLFRAVPANAAVFYIFETLS 290 Score = 35.4 bits (80), Expect = 0.13 Identities = 19/92 (20%), Positives = 42/92 (45%), Gaps = 10/92 (10%) Frame = +2 Query: 119 TGVWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQ----------VAKTMYA 268 T V+ + ++GG +G A+ V+ P++++K K+Q+ A K + Sbjct: 102 TNVFPLGQILISGGVAGSCASLVLTPVELVKCKLQVANLQVASAKTKHTKVLPTIKAIIT 161 Query: 269 NEGLGSFYKGLSAGLLRQATYTTARLGSFRVL 364 GL ++G S +R++ A ++ ++ Sbjct: 162 ERGLAGLWQGQSGTFIRESFGGVAWFATYEIV 193
>MFRN1_RAT (Q66H23) Mitoferrin-1 (Mitochondrial iron transporter 1) (Solute| carrier family 25 member 37) Length = 338 Score = 44.7 bits (104), Expect = 2e-04 Identities = 35/153 (22%), Positives = 66/153 (43%), Gaps = 9/153 (5%) Frame = +2 Query: 149 VNGGASGMLATCVIQPIDMIKVKIQLGEG---SAAQVAKTMYANEGLGSFYKGLSAGLLR 319 + G + +L V+ P +++K ++Q+ SA +T++ EGLG+FY+ + L Sbjct: 148 IAGSMATLLHDAVMNPAEVVKQRLQMYNSQHQSALSCIRTVWRTEGLGAFYRSYTTQLTM 207 Query: 320 QATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADL--ALIRM 493 + + ++ L + D P + G AGA+ A +P D+ L+ Sbjct: 208 NIPFQSIHFITYEFLQEQVNPRRDYNPQSHI---ISGGLAGALAAAATTPLDVCKTLLNT 264 Query: 494 QADSTLPAA----QRRHYKNAFHALYRITADEG 580 Q + L A + NAF +Y++ G Sbjct: 265 QENMALSLANVSGRLSGMANAFRTVYQLNGLAG 297 Score = 36.2 bits (82), Expect = 0.074 Identities = 22/91 (24%), Positives = 38/91 (41%), Gaps = 13/91 (14%) Frame = +2 Query: 101 QQAAAPTGVWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVA--------- 253 Q+ P + ++GG +G LA P+D+ K + E A +A Sbjct: 223 QEQVNPRRDYNPQSHIISGGLAGALAAAATTPLDVCKTLLNTQENMALSLANVSGRLSGM 282 Query: 254 ----KTMYANEGLGSFYKGLSAGLLRQATYT 334 +T+Y GL ++KG+ A ++ Q T Sbjct: 283 ANAFRTVYQLNGLAGYFKGIQARVIYQMPST 313
>MFRN1_MOUSE (Q920G8) Mitoferrin-1 (Mitochondrial iron transporter 1) (Solute| carrier family 25 member 37) (Mitochondria solute carrier protein) Length = 338 Score = 44.7 bits (104), Expect = 2e-04 Identities = 36/153 (23%), Positives = 66/153 (43%), Gaps = 9/153 (5%) Frame = +2 Query: 149 VNGGASGMLATCVIQPIDMIKVKIQLGEG---SAAQVAKTMYANEGLGSFYKGLSAGLLR 319 V G + +L V+ P +++K ++Q+ SA +T++ EGLG+FY+ + L Sbjct: 148 VAGSMATLLHDAVMNPAEVVKQRLQMYNSQHQSAFSCIRTVWRTEGLGAFYRSYTTQLTM 207 Query: 320 QATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADL--ALIRM 493 + + ++ L + D P + G AGA+ A +P D+ L+ Sbjct: 208 NIPFQSIHFITYEFLQEQVNPRRDYNPQSHI---ISGGLAGALAAAATTPLDVCKTLLNT 264 Query: 494 QADSTLPAA----QRRHYKNAFHALYRITADEG 580 Q + L A + NAF +Y++ G Sbjct: 265 QENMALSLANVSGRLSGMANAFRTVYQLNGLAG 297 Score = 37.0 bits (84), Expect = 0.044 Identities = 25/111 (22%), Positives = 45/111 (40%), Gaps = 17/111 (15%) Frame = +2 Query: 101 QQAAAPTGVWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVA--------- 253 Q+ P + ++GG +G LA P+D+ K + E A +A Sbjct: 223 QEQVNPRRDYNPQSHIISGGLAGALAAAATTPLDVCKTLLNTQENMALSLANVSGRLSGM 282 Query: 254 ----KTMYANEGLGSFYKGLSAGLLRQATYTTARLGSFR----VLTNKAIE 382 +T+Y GL ++KG+ A ++ Q T + +LT + +E Sbjct: 283 ANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFKYILTKRQLE 333
>CMC1_CAEEL (Q21153) Probable calcium-binding mitochondrial carrier K02F3.2| Length = 707 Score = 44.7 bits (104), Expect = 2e-04 Identities = 38/162 (23%), Positives = 68/162 (41%), Gaps = 11/162 (6%) Frame = +2 Query: 146 FVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAKTMYAN-----------EGLGSFY 292 F+ G +G + PID++K ++Q S + V + MY N EGL Y Sbjct: 373 FLLGSVAGACGATAVYPIDLVKTRMQNQRTSGSFVGEVMYKNSLDCFKKVVKFEGLLGLY 432 Query: 293 KGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPA 472 +GL ++ A +L + +K DG+ +PL + G T G +P Sbjct: 433 RGLLPQIVGVAPEKAIKLTMNDYMRDKF--TKDGK-IPLYGEIIAGGTGGMCQVVFTNPL 489 Query: 473 DLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 ++ IR+Q + A ++ ++ + + G L L+K Sbjct: 490 EIVKIRLQTAGEVQQAGKK------IGVFTVLKELGFLGLYK 525
>CMC2_CAEEL (Q20799) Probable calcium-binding mitochondrial carrier F55A11.4| Length = 588 Score = 44.3 bits (103), Expect = 3e-04 Identities = 36/180 (20%), Positives = 74/180 (41%), Gaps = 5/180 (2%) Frame = +2 Query: 74 PEEMADAKQQQAAAPTGVWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVA 253 PE+ + + Q+ G+W + V GGA+G ++ P D IKV +Q+ ++ Sbjct: 235 PEDFSQQEMQE-----GIWW--RHLVAGGAAGAVSRTCTAPFDRIKVYLQVNSSKTNRLG 287 Query: 254 -----KTMYANEGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQK 418 K ++A G+ SF++G +++ A + + + L + + ++ Sbjct: 288 VMSCLKLLHAEGGIKSFWRGNGINVIKIAPESAIKFMCYDQLKRLIQKKKGNEEISTFER 347 Query: 419 AFIGLTAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 G AGAI P ++ R+ T + + H +++ EG+ +K Sbjct: 348 LCAGSAAGAISQSTIYPMEVMKTRLALRKT-----GQLDRGIIHFAHKMYTKEGIRCFYK 402 Score = 39.3 bits (90), Expect = 0.009 Identities = 33/130 (25%), Positives = 50/130 (38%), Gaps = 8/130 (6%) Frame = +2 Query: 134 TIKPFVNGGASGMLATCVIQPIDMIKVKIQLG-----EGSAAQVAKTMYANEGLGSFYKG 298 T + G A+G ++ I P++++K ++ L + A MY EG+ FYKG Sbjct: 344 TFERLCAGSAAGAISQSTIYPMEVMKTRLALRKTGQLDRGIIHFAHKMYTKEGIRCFYKG 403 Query: 299 LSAGLLRQATYTTARLGSFRVLTNKAI---EANDGRPLPLVQKAFIGLTAGAIGACVGSP 469 L+ Y L + L + E N P L A G + G P Sbjct: 404 YLPNLIGIIPYAGIDLAIYETLKRTYVRYYETNSSEPGVLALLA-CGTCSSTCGQLSSYP 462 Query: 470 ADLALIRMQA 499 L R+QA Sbjct: 463 FALVRTRLQA 472
>YFL5_YEAST (P43617) Putative mitochondrial carrier YFR045W| Length = 285 Score = 44.3 bits (103), Expect = 3e-04 Identities = 28/115 (24%), Positives = 44/115 (38%) Frame = +2 Query: 254 KTMYANEGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGL 433 K MY G +F +G +A + RQ T+ + ++ ND GL Sbjct: 148 KHMYQTRGPAAFVQGTTATIFRQIANTSIQFTAYTAFKRLLQARNDK-----ASSVITGL 202 Query: 434 TAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 + P D+ RM + + + YKN + +YRI EG+ WK Sbjct: 203 ATSFTLVAMTQPIDVVKTRMMSQNA-----KTEYKNTLNCMYRIFVQEGMATFWK 252
>TXTP_RAT (P32089) Tricarboxylate transport protein, mitochondrial precursor| (Citrate transport protein) (CTP) (Tricarboxylate carrier protein) (Solute carrier family 25 member 1) Length = 311 Score = 44.3 bits (103), Expect = 3e-04 Identities = 41/155 (26%), Positives = 65/155 (41%), Gaps = 8/155 (5%) Frame = +2 Query: 158 GASGMLATCVIQPIDMIKVKIQLGEGSAAQVAKTMY-------ANEGLGSFYKGLSAGLL 316 GA A V+ P++ +KVK + S+ + + +GL Y+GL+A +L Sbjct: 130 GAGVAEAVVVVCPMETVKVKFIHDQTSSNPKYRGFFHGVREIVREQGLKGTYQGLTATVL 189 Query: 317 RQATYTTARLGSFRVLTNKAIEANDGRPL-PLVQKAFIGLTAGAIGACVGSPADLALIRM 493 +Q + R L N N +P+ PL+ F G AGA +P D+ RM Sbjct: 190 KQGSNQAIRFFVMTSLRNWYQGDNPNKPMNPLITGVF-GAVAGAASVFGNTPLDVIKTRM 248 Query: 494 QADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 Q + Y+N +I +EG A +K Sbjct: 249 Q------GLEAHKYRNTLDCGVQILKNEGPKAFYK 277
>TXTP_HUMAN (P53007) Tricarboxylate transport protein, mitochondrial precursor| (Citrate transport protein) (CTP) (Tricarboxylate carrier protein) (Solute carrier family 25 member 1) Length = 311 Score = 44.3 bits (103), Expect = 3e-04 Identities = 42/155 (27%), Positives = 65/155 (41%), Gaps = 8/155 (5%) Frame = +2 Query: 158 GASGMLATCVIQPIDMIKVKIQLGEGSAAQVAKTMY-------ANEGLGSFYKGLSAGLL 316 GA A V+ P++ IKVK + S + + +GL Y+GL+A +L Sbjct: 130 GAGVAEAVVVVCPMETIKVKFIHDQTSPNPKYRGFFHGVREIVREQGLKGTYQGLTATVL 189 Query: 317 RQATYTTARLGSFRVLTNKAIEANDGRPL-PLVQKAFIGLTAGAIGACVGSPADLALIRM 493 +Q + R L N N +P+ PL+ F G AGA +P D+ RM Sbjct: 190 KQGSNQAIRFFVMTSLRNWYRGDNPNKPMNPLITGVF-GAIAGAASVFGNTPLDVIKTRM 248 Query: 494 QADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 Q + Y+N + +I EG+ A +K Sbjct: 249 Q------GLEAHKYRNTWDCGLQILKKEGLKAFYK 277
>GHC1_HUMAN (Q9H936) Mitochondrial glutamate carrier 1 (GC-1) (Glutamate/H(+)| symporter 1) (Solute carrier family 25 member 22) Length = 323 Score = 43.9 bits (102), Expect = 4e-04 Identities = 33/134 (24%), Positives = 64/134 (47%), Gaps = 7/134 (5%) Frame = +2 Query: 149 VNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAKTM-------YANEGLGSFYKGLSA 307 +NGG +G++ + PID+ K ++Q + + +V +M +EG Y+G + Sbjct: 13 INGGIAGLIGVTCVFPIDLAKTRLQ-NQQNGQRVYTSMSDCLIKTVRSEGYFGMYRGAAV 71 Query: 308 GLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLALI 487 L +L + ++ + DG+ L L+++ G AG V +P ++ I Sbjct: 72 NLTLVTPEKAIKLAANDFFRHQL--SKDGQKLTLLKEMLAGCGAGTCQVIVTTPMEMLKI 129 Query: 488 RMQADSTLPAAQRR 529 ++Q D+ AAQR+ Sbjct: 130 QLQ-DAGRIAAQRK 142 Score = 39.3 bits (90), Expect = 0.009 Identities = 23/88 (26%), Positives = 39/88 (44%) Frame = +2 Query: 236 SAAQVAKTMYANEGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQ 415 +A Q+ + + + G+ YKGL A LLR ++ F L A++ + P Sbjct: 169 TATQLTRDLLRSRGIAGLYKGLGATLLRDVPFSVVYFPLFANLNQLGRPASEEKS-PFYV 227 Query: 416 KAFIGLTAGAIGACVGSPADLALIRMQA 499 G AG+ A +P D+ R+Q+ Sbjct: 228 SFLAGCVAGSAAAVAVNPCDVVKTRLQS 255
>MRS3_YEAST (P10566) Mitochondrial RNA-splicing protein MRS3| Length = 314 Score = 43.9 bits (102), Expect = 4e-04 Identities = 35/159 (22%), Positives = 67/159 (42%), Gaps = 6/159 (3%) Frame = +2 Query: 140 KPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAA-QVAKTMYANEGLGSFYKGLSAGLL 316 K ++G + + ++ P D IK +IQL ++ Q K +Y +EGL +FY L+ Sbjct: 132 KTAISGACATTASDALMNPFDTIKQRIQLNTSASVWQTTKQIYQSEGLAAFYYSYPTTLV 191 Query: 317 RQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADL--ALIR 490 + + T +N+ PL G +G+ A + +P D +++ Sbjct: 192 MNIPFAAFNFVIYESSTKFLNPSNEYNPL---IHCLCGSISGSTCAAITTPLDCIKTVLQ 248 Query: 491 MQADSTLPAAQRRH---YKNAFHALYRITADEGVLALWK 598 ++ T+ R + A A+Y++ +G WK Sbjct: 249 IRGSQTVSLEIMRKADTFSKAASAIYQVYGWKGFWRGWK 287 Score = 33.5 bits (75), Expect = 0.48 Identities = 27/127 (21%), Positives = 55/127 (43%), Gaps = 7/127 (5%) Frame = +2 Query: 149 VNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAKTMYA-------NEGLGSFYKGLSA 307 + G +G++ V+ PID +K +IQ + AK M + +EG + +KG+ + Sbjct: 38 IAGAFAGIMEHSVMFPIDALKTRIQSANAKSLS-AKNMLSQISHISTSEGTLALWKGVQS 96 Query: 308 GLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLALI 487 +L G++ I+++D + + A G A + +P D Sbjct: 97 VILGAGPAHAVYFGTYEFCKKNLIDSSDTQTHHPFKTAISGACATTASDALMNPFDTIKQ 156 Query: 488 RMQADST 508 R+Q +++ Sbjct: 157 RIQLNTS 163
>PIC2_YEAST (P40035) Mitochondrial phosphate carrier protein 2 (Phosphate| transport protein 2) (PTP 2) (mPic 2) (Pi carrier isoform 2) Length = 300 Score = 43.5 bits (101), Expect = 5e-04 Identities = 38/137 (27%), Positives = 63/137 (45%), Gaps = 15/137 (10%) Frame = +2 Query: 173 LATCVIQPIDMIKVKIQLGE----GSAAQVAKTMYANEG-LGSFYKGLSAGLLRQATYTT 337 LA ++ P + IKVK Q + K MYA G + +FYKG+ RQ YT Sbjct: 122 LADIMLCPFEAIKVKQQTTMPPFCNNVVDGWKKMYAESGGMKAFYKGIVPLWCRQIPYTM 181 Query: 338 ARLGSFRVLTNKAI-----EANDGRPLPLVQKAFI-GLTAGAIGACVGSPADLALIRM-- 493 + SF + K + + L + +F+ G AG + A V PAD+ + ++ Sbjct: 182 CKFTSFEKIVQKIYSVLPKKKEEMNALQQISVSFVGGYLAGILCAAVSHPADVMVSKINS 241 Query: 494 --QADSTLPAAQRRHYK 538 +A+ ++ A +R Y+ Sbjct: 242 ERKANESMSVASKRIYQ 258
>GHC1_PONPY (Q5RD81) Mitochondrial glutamate carrier 1 (GC-1) (Glutamate/H(+)| symporter 1) (Solute carrier family 25 member 22) Length = 323 Score = 43.5 bits (101), Expect = 5e-04 Identities = 32/133 (24%), Positives = 61/133 (45%), Gaps = 6/133 (4%) Frame = +2 Query: 149 VNGGASGMLATCVIQPIDMIKVKIQLGEG------SAAQVAKTMYANEGLGSFYKGLSAG 310 +NGG +G++ + PID+ K ++Q + S + +EG Y+G + Sbjct: 13 INGGIAGLIGVTCVFPIDLAKTRLQNQQNGQRMYTSMSDCLIKTIRSEGYFGMYRGAAVN 72 Query: 311 LLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLALIR 490 L +L + ++ + DG+ L L+++ G AG V +P ++ I+ Sbjct: 73 LTLVTPEKAIKLAANDFFRHQL--SKDGQKLTLLKEMLAGCGAGTCQVIVTTPMEMLKIQ 130 Query: 491 MQADSTLPAAQRR 529 +Q D+ AAQR+ Sbjct: 131 LQ-DAGRIAAQRK 142 Score = 37.4 bits (85), Expect = 0.033 Identities = 23/88 (26%), Positives = 38/88 (43%) Frame = +2 Query: 236 SAAQVAKTMYANEGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQ 415 +A Q+ + + + G+ YKGL A LLR + F L A++ + P Sbjct: 169 TAIQLTRDLLRSRGIAGLYKGLGATLLRDVPLSVVYFPLFANLNQLGRPASEEKS-PFYV 227 Query: 416 KAFIGLTAGAIGACVGSPADLALIRMQA 499 G AG+ A +P D+ R+Q+ Sbjct: 228 SFLAGCVAGSAAAVAVNPCDVVKTRLQS 255
>GHC1_MOUSE (Q9D6M3) Mitochondrial glutamate carrier 1 (GC-1) (Glutamate/H(+)| symporter 1) (Solute carrier family 25 member 22) Length = 323 Score = 43.5 bits (101), Expect = 5e-04 Identities = 34/134 (25%), Positives = 62/134 (46%), Gaps = 7/134 (5%) Frame = +2 Query: 149 VNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVA-------KTMYANEGLGSFYKGLSA 307 +NGG +G++ + PID+ K ++Q + A KT+ +EG Y+G + Sbjct: 13 INGGIAGLIGVTCVFPIDLAKTRLQNQQNGQRMYASMSDCLIKTI-RSEGYFGMYRGAAV 71 Query: 308 GLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLALI 487 L +L + ++ + DG+ L L ++ G AG V +P ++ I Sbjct: 72 NLTLVTPEKAIKLAANDFFRHQL--SKDGQKLTLPKEMLAGCGAGTCQVIVTTPMEMLKI 129 Query: 488 RMQADSTLPAAQRR 529 ++Q D+ AAQR+ Sbjct: 130 QLQ-DAGRIAAQRK 142 Score = 39.7 bits (91), Expect = 0.007 Identities = 24/88 (27%), Positives = 38/88 (43%) Frame = +2 Query: 236 SAAQVAKTMYANEGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQ 415 +A Q+ + + N G+ YKGL A LLR ++ F L N+ + P Sbjct: 169 TATQLTRDLLRNHGIAGLYKGLGATLLRDVPFSIVYFPLFANL-NQLGRPSSEEKSPFYV 227 Query: 416 KAFIGLTAGAIGACVGSPADLALIRMQA 499 G AG+ A +P D+ R+Q+ Sbjct: 228 SFLAGCVAGSAAAVAVNPCDVVKTRLQS 255
>MFRN1_HUMAN (Q9NYZ2) Mitoferrin-1 (Mitochondrial iron transporter 1) (Solute| carrier family 25 member 37) (Mitochondria solute carrier protein) Length = 347 Score = 42.4 bits (98), Expect = 0.001 Identities = 34/148 (22%), Positives = 64/148 (43%), Gaps = 9/148 (6%) Frame = +2 Query: 149 VNGGASGMLATCVIQPIDMIKVKIQLGEG---SAAQVAKTMYANEGLGSFYKGLSAGLLR 319 + G + +L V+ P +++K ++Q+ SA +T++ EGLG+FY+ + L Sbjct: 148 IAGSMATLLHDAVMNPAEVVKQRLQMYNSQHRSAISCIRTVWRTEGLGAFYRSYTTQLTM 207 Query: 320 QATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADL--ALIRM 493 + + ++ L + N R G AGA+ A +P D+ L+ Sbjct: 208 NIPFQSIHFITYEFLQE---QVNPHRTYNPQSHIISGGLAGALAAAATTPLDVCKTLLNT 264 Query: 494 QADSTLPAA----QRRHYKNAFHALYRI 565 Q + L A + NAF +Y++ Sbjct: 265 QENVALSLANISGRLSGMANAFRTVYQL 292
>ADT_DROME (Q26365) ADP,ATP carrier protein (ADP/ATP translocase) (Adenine| nucleotide translocator) (ANT) (Stress sensitive B protein) Length = 312 Score = 42.4 bits (98), Expect = 0.001 Identities = 35/157 (22%), Positives = 56/157 (35%), Gaps = 8/157 (5%) Frame = +2 Query: 152 NGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAKT--------MYANEGLGSFYKGLSA 307 +GGA+G + C + P+D + ++ G Q T ++ ++G+ Y+G Sbjct: 134 SGGAAGATSLCFVYPLDFARTRLAADTGKGGQREFTGLGNCLTKIFKSDGIVGLYRGFGV 193 Query: 308 GLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLALI 487 + Y A G + D + P+ I + V P D Sbjct: 194 SVQGIIIYRAAYFGFYDTARGM---LPDPKNTPIYISWAIAQVVTTVAGIVSYPFDTVRR 250 Query: 488 RMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 RM S A + YKN H I EG A +K Sbjct: 251 RMMMQSGRKATE-VIYKNTLHCWATIAKQEGTGAFFK 286
>ADT1_MOUSE (P48962) ADP/ATP translocase 1 (Adenine nucleotide translocator 1)| (ANT 1) (ADP,ATP carrier protein 1) (Solute carrier family 25 member 4) (ADP,ATP carrier protein, heart/skeletal muscle isoform T1) (mANC1) Length = 297 Score = 42.0 bits (97), Expect = 0.001 Identities = 37/158 (23%), Positives = 64/158 (40%), Gaps = 9/158 (5%) Frame = +2 Query: 152 NGGASGMLATCVIQPIDMIKVKI--QLGEGSA-------AQVAKTMYANEGLGSFYKGLS 304 +GGA+G + C + P+D + ++ +G+GS+ ++ ++GL Y+G S Sbjct: 118 SGGAAGATSLCFVYPLDFARTRLAADVGKGSSQREFNGLGDCLTKIFKSDGLKGLYQGFS 177 Query: 305 AGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLAL 484 + Y A G + T K + D + + ++ I + A+ V P D Sbjct: 178 VSVQGIIIYRAAYFGVYD--TAKGM-LPDPKNVHIIVSWMIAQSVTAVAGLVSYPFDTVR 234 Query: 485 IRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 RM S A Y +I DEG A +K Sbjct: 235 RRMMMQSGRKGADIM-YTGTLDCWRKIAKDEGANAFFK 271
>CRC1_YEAST (Q12289) Mitochondrial carnitine carrier| Length = 327 Score = 42.0 bits (97), Expect = 0.001 Identities = 34/125 (27%), Positives = 51/125 (40%), Gaps = 7/125 (5%) Frame = +2 Query: 155 GGASGMLATCVIQPIDMIKVKIQLG-EGSAAQVAKTMYANEGLGSFYKGLSAGLLRQATY 331 G S + T V P + +KV +Q +GS Q AKT+ G+ S +KG A L R Sbjct: 148 GFISAIPTTLVTAPTERVKVVLQTSSKGSFIQAAKTIVKEGGIASLFKGSLATLARDGPG 207 Query: 332 TTARLGSFRVLTN------KAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLALIRM 493 + S+ + N +A P+ ++ G AG P D ++ Sbjct: 208 SALYFASYEISKNYLNSRQPRQDAGKDEPVNILNVCLAGGIAGMSMWLAVFPIDTIKTKL 267 Query: 494 QADST 508 QA ST Sbjct: 268 QASST 272 Score = 41.6 bits (96), Expect = 0.002 Identities = 50/203 (24%), Positives = 78/203 (38%), Gaps = 20/203 (9%) Frame = +2 Query: 50 LSQPG*ISPEEMADAKQQQAAAPTGVWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQLG 229 LS+ + E + K + V + IK FV GG G+ A P D+IKV+ Q G Sbjct: 7 LSESSLLKEESGSLTKSRPPIKSNPVRENIKSFVAGGVGGVCAVFTGHPFDLIKVRCQNG 66 Query: 230 EGSA-------------AQVAKTMYANEGLGSFYKGLSAGLLRQATYTTARLGSFRV--- 361 + ++ QV T++ N G FYKG+ LL + V Sbjct: 67 QANSTVHAITNIIKEAKTQVKGTLFTNSVKG-FYKGVIPPLLGVTPIFAVSFWGYDVGKK 125 Query: 362 ---LTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLALIRMQADSTLPAAQRRH 532 NK +N+ L + Q A G + V +P + + +Q S Sbjct: 126 LVTFNNKQGGSNE---LTMGQMAAAGFISAIPTTLVTAPTERVKVVLQTSS--------- 173 Query: 533 YKNAF-HALYRITADEGVLALWK 598 K +F A I + G+ +L+K Sbjct: 174 -KGSFIQAAKTIVKEGGIASLFK 195
>ODC1_YEAST (Q03028) Mitochondrial 2-oxodicarboxylate carrier 1| Length = 310 Score = 42.0 bits (97), Expect = 0.001 Identities = 38/143 (26%), Positives = 63/143 (44%), Gaps = 23/143 (16%) Frame = +2 Query: 137 IKPFVNGGASGMLATCVIQPIDMIKVKIQLGEGS-------AAQVAKTMYAN-------- 271 I F G +G+ V+ P+D++K ++QL + AA+ A Y Sbjct: 12 IYQFTAGAIAGVSELLVMYPLDVVKTRMQLQVTTKGHPAVVAAKAAVDHYTGVMDCLTKI 71 Query: 272 ---EGLGSFYKGLSAGLLRQATYTTARLG---SFRVLTNKAIEANDGRPLPLVQKAFI-- 427 EG YKG+++ +L +A + +F+ K +G + QK I Sbjct: 72 VKKEGFSHLYKGITSPILMEAPKRAIKFSGNDTFQTFYKKIFPTPNGE---MTQKIAIYS 128 Query: 428 GLTAGAIGACVGSPADLALIRMQ 496 G +AGA+ A V +P +L IR+Q Sbjct: 129 GASAGAVEAFVVAPFELVKIRLQ 151 Score = 33.5 bits (75), Expect = 0.48 Identities = 26/78 (33%), Positives = 31/78 (39%), Gaps = 8/78 (10%) Frame = +2 Query: 389 DGRPLPLVQKAFIGLTAGAIGACVGSPADLALIRMQADSTL---PA-----AQRRHYKNA 544 D RPLP + + G AG V P D+ RMQ T PA A HY Sbjct: 5 DNRPLPFIYQFTAGAIAGVSELLVMYPLDVVKTRMQLQVTTKGHPAVVAAKAAVDHYTGV 64 Query: 545 FHALYRITADEGVLALWK 598 L +I EG L+K Sbjct: 65 MDCLTKIVKKEGFSHLYK 82
>ADT1_HUMAN (P12235) ADP/ATP translocase 1 (Adenine nucleotide translocator 1)| (ANT 1) (ADP,ATP carrier protein 1) (Solute carrier family 25 member 4) (ADP,ATP carrier protein, heart/skeletal muscle isoform T1) Length = 297 Score = 41.6 bits (96), Expect = 0.002 Identities = 38/171 (22%), Positives = 68/171 (39%), Gaps = 14/171 (8%) Frame = +2 Query: 128 WKTIKPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAKTMY-----------ANE 274 W +K F+ GG + ++ + PI+ +K+ +Q+ S A+ Y + Sbjct: 5 WSFLKDFLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQ 64 Query: 275 GLGSFYKGLSAGLLR---QATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGA 445 G SF++G A ++R A ++ L ++ + G AGA Sbjct: 65 GFLSFWRGNLANVIRYFPTQALNFAFKDKYKQLFLGGVDRHKQFWRYFAGNLASGGAAGA 124 Query: 446 IGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 C P D A R+ AD AAQ R + + +I +G+ L++ Sbjct: 125 TSLCFVYPLDFARTRLAADVGKGAAQ-REFHGLGDCIIKIFKSDGLRGLYQ 174
>ORNT1_MOUSE (Q9WVD5) Mitochondrial ornithine transporter 1 (Solute carrier| family 25 member 15) Length = 301 Score = 41.2 bits (95), Expect = 0.002 Identities = 36/121 (29%), Positives = 48/121 (39%), Gaps = 7/121 (5%) Frame = +2 Query: 155 GGASGMLATCVIQPIDMIKVKIQ----LGEGSAAQVAKTMYANEGLGSFYKGLSAGLLRQ 322 G A G QP D +KVK+Q L G KT Y+ G FYKG S L+ Sbjct: 16 GAAGGTACVLTGQPFDTMKVKMQTFPDLYRGLTDCCLKT-YSQVGFRGFYKGTSPALIAN 74 Query: 323 ATYTTARL---GSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLALIRM 493 + G + + K + + L +Q A G A A A V P +L R+ Sbjct: 75 IAENSVLFMCYGFCQQVVRKVVGLDQQAKLSDLQNAAAGSFASAFAALVLCPTELVKCRL 134 Query: 494 Q 496 Q Sbjct: 135 Q 135 Score = 32.0 bits (71), Expect = 1.4 Identities = 17/62 (27%), Positives = 31/62 (50%), Gaps = 5/62 (8%) Frame = +2 Query: 149 VNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVA-----KTMYANEGLGSFYKGLSAGL 313 ++GG G+ + P+D IK +IQ+ + Q ++ NEG+ + Y GL + Sbjct: 214 LSGGFGGICLWLAVYPVDCIKSRIQVLSMTGKQTGLVRTFLSIVKNEGITALYSGLKPTM 273 Query: 314 LR 319 +R Sbjct: 274 IR 275 Score = 30.4 bits (67), Expect = 4.1 Identities = 20/68 (29%), Positives = 35/68 (51%), Gaps = 12/68 (17%) Frame = +2 Query: 155 GGASGMLATCVIQPIDMIKVKIQL-------GEGSAAQ-----VAKTMYANEGLGSFYKG 298 G + A V+ P +++K ++Q G+ +A+Q V K ++ +G FY G Sbjct: 113 GSFASAFAALVLCPTELVKCRLQTMYEMETSGKIAASQNTVWSVVKEIFRKDGPLGFYHG 172 Query: 299 LSAGLLRQ 322 LS+ LLR+ Sbjct: 173 LSSTLLRE 180
>ADT1_RAT (Q05962) ADP/ATP translocase 1 (Adenine nucleotide translocator 1)| (ANT 1) (ADP,ATP carrier protein 1) (Solute carrier family 25 member 4) Length = 297 Score = 40.8 bits (94), Expect = 0.003 Identities = 37/158 (23%), Positives = 64/158 (40%), Gaps = 9/158 (5%) Frame = +2 Query: 152 NGGASGMLATCVIQPIDMIKVKI--QLGEGSA-------AQVAKTMYANEGLGSFYKGLS 304 +GGA+G + C + P+D + ++ +G+GS+ ++ ++GL Y+G S Sbjct: 118 SGGAAGATSLCFVYPLDFARTRLAADVGKGSSQREFNGLGDCLTKIFKSDGLKGLYQGFS 177 Query: 305 AGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLAL 484 + Y A G + T K + D + + ++ I + A+ V P D Sbjct: 178 VSVQGIIIYRAAYFGVYD--TAKGM-LPDPKNVHIIVSWMIAQSVTAVAGLVSYPFDTVR 234 Query: 485 IRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 RM S A Y +I DEG A +K Sbjct: 235 RRMMMQSGRKGADIM-YTGTVDCWRKIAKDEGRKAFFK 271
>ORNT2_HUMAN (Q9BXI2) Mitochondrial ornithine transporter 2 (Solute carrier| family 25 member 2) Length = 301 Score = 39.7 bits (91), Expect = 0.007 Identities = 37/121 (30%), Positives = 46/121 (38%), Gaps = 7/121 (5%) Frame = +2 Query: 155 GGASGMLATCVIQPIDMIKVKIQ----LGEGSAAQVAKTMYANEGLGSFYKGLSAGLLRQ 322 G A G QP D IKVK+Q L +G KT YA GL FYKG L+ Sbjct: 16 GAAGGTACVLTGQPFDTIKVKMQTFPDLYKGLTDCFLKT-YAQVGLRGFYKGTGPALMAY 74 Query: 323 ATYTTARL---GSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLALIRM 493 + G + K + L +Q A G A A A P +L R+ Sbjct: 75 VAENSVLFMCYGFCQQFVRKVAGMDKQAKLSDLQTAAAGSFASAFAALALCPTELVKCRL 134 Query: 494 Q 496 Q Sbjct: 135 Q 135 Score = 34.7 bits (78), Expect = 0.22 Identities = 20/62 (32%), Positives = 35/62 (56%), Gaps = 5/62 (8%) Frame = +2 Query: 149 VNGGASGMLATCVIQPIDMIKVKIQLGE--GSAAQVAKTMYA---NEGLGSFYKGLSAGL 313 ++GG +G+ ++ P+D IK +IQ+ G A T+ + NEG+ + Y GL A + Sbjct: 214 LSGGVAGICLWLIVFPVDCIKSRIQVLSMYGKQAGFIGTLLSVVRNEGIVALYSGLKATM 273 Query: 314 LR 319 +R Sbjct: 274 IR 275
>GHC2_MOUSE (Q9DB41) Mitochondrial glutamate carrier 2 (GC-2) (Glutamate/H(+)| symporter 2) (Solute carrier family 25 member 18) (Fragment) Length = 312 Score = 39.7 bits (91), Expect = 0.007 Identities = 24/87 (27%), Positives = 38/87 (43%) Frame = +2 Query: 236 SAAQVAKTMYANEGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQ 415 SA +A+ + +GL Y+GL A LLR ++ F L + G+ Sbjct: 162 SATLIARELLRTQGLSGLYRGLGATLLRDIPFSIIYFPLFANLNQLGVSELTGK-ASFTH 220 Query: 416 KAFIGLTAGAIGACVGSPADLALIRMQ 496 G TAG++ A +P D+ R+Q Sbjct: 221 SFVAGCTAGSVAAVAVTPLDVLKTRIQ 247 Score = 36.6 bits (83), Expect = 0.057 Identities = 29/122 (23%), Positives = 51/122 (41%), Gaps = 6/122 (4%) Frame = +2 Query: 149 VNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQ------VAKTMYANEGLGSFYKGLSAG 310 +NGG +G++ + PID+ K ++Q +G + KT A EG Y+G + Sbjct: 10 INGGIAGLVGVTCVFPIDLAKTRLQNQQGKDVYRGMTDCLMKTARA-EGFLGMYRGAAVN 68 Query: 311 LLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLALIR 490 L +L + L + + DG L + G AG + P ++ I+ Sbjct: 69 LTLVTPEKAIKLAANDFL--RQLLMQDGTQRNLKMEMLAGCGAGICQVVITCPMEMLKIQ 126 Query: 491 MQ 496 +Q Sbjct: 127 LQ 128
>YEA6_YEAST (P39953) Putative mitochondrial carrier YEL006W| Length = 335 Score = 39.3 bits (90), Expect = 0.009 Identities = 40/162 (24%), Positives = 64/162 (39%), Gaps = 13/162 (8%) Frame = +2 Query: 149 VNGGASGMLATCVIQPIDMIKVKIQLG------------EGSAAQVAKTMYANEGLGSFY 292 ++G SG L+ ++ P D+ K ++Q +G A T++ +EG Y Sbjct: 43 ISGALSGALSAMLVCPFDVAKTRLQAQGLQNMTHQSQHYKGFFGTFA-TIFKDEGAAGLY 101 Query: 293 KGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRP-LPLVQKAFIGLTAGAIGACVGSP 469 KGL +L Y + F V + D P P + A +TAGAI +P Sbjct: 102 KGLQPTVL---GYIPTLMIYFSVYDFCRKYSVDIFPHSPFLSNASSAITAGAISTVATNP 158 Query: 470 ADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALW 595 + R+ + + HYK +I EG AL+ Sbjct: 159 IWVVKTRLMLQTGI-GKYSTHYKGTIDTFRKIIQQEGAKALY 199 Score = 36.2 bits (82), Expect = 0.074 Identities = 22/61 (36%), Positives = 29/61 (47%), Gaps = 1/61 (1%) Frame = +2 Query: 419 AFIGLTAGAIGACVGSPADLALIRMQADSTLPAA-QRRHYKNAFHALYRITADEGVLALW 595 A G +GA+ A + P D+A R+QA Q +HYK F I DEG L+ Sbjct: 42 AISGALSGALSAMLVCPFDVAKTRLQAQGLQNMTHQSQHYKGFFGTFATIFKDEGAAGLY 101 Query: 596 K 598 K Sbjct: 102 K 102
>ORNT1_HUMAN (Q9Y619) Mitochondrial ornithine transporter 1 (Solute carrier| family 25 member 15) Length = 301 Score = 39.3 bits (90), Expect = 0.009 Identities = 36/121 (29%), Positives = 47/121 (38%), Gaps = 7/121 (5%) Frame = +2 Query: 155 GGASGMLATCVIQPIDMIKVKIQ----LGEGSAAQVAKTMYANEGLGSFYKGLSAGLLRQ 322 G A G QP D +KVK+Q L G KT Y+ G FYKG S L+ Sbjct: 16 GAAGGTACVLTGQPFDTMKVKMQTFPDLYRGLTDCCLKT-YSQVGFRGFYKGTSPALIAN 74 Query: 323 ATYTTARL---GSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLALIRM 493 + G + + K + L +Q A G A A A V P +L R+ Sbjct: 75 IAENSVLFMCYGFCQQVVRKVAGLDKQAKLSDLQNAAAGSFASAFAALVLCPTELVKCRL 134 Query: 494 Q 496 Q Sbjct: 135 Q 135 Score = 33.1 bits (74), Expect = 0.63 Identities = 18/62 (29%), Positives = 30/62 (48%), Gaps = 5/62 (8%) Frame = +2 Query: 149 VNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVA-----KTMYANEGLGSFYKGLSAGL 313 ++GG G+ + P+D IK +IQ+ S Q + NEG+ + Y GL + Sbjct: 214 LSGGVGGICLWLAVYPVDCIKSRIQVLSMSGKQAGFIRTFINVVKNEGITALYSGLKPTM 273 Query: 314 LR 319 +R Sbjct: 274 IR 275
>ADT1_RABIT (O46373) ADP/ATP translocase 1 (Adenine nucleotide translocator 1)| (ANT 1) (ADP,ATP carrier protein 1) (Solute carrier family 25 member 4) (30 kDa calsequestrin-binding protein) (CSQ-binding 30 kDa protein) Length = 297 Score = 38.9 bits (89), Expect = 0.011 Identities = 37/168 (22%), Positives = 68/168 (40%), Gaps = 14/168 (8%) Frame = +2 Query: 137 IKPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAKTMY-----------ANEGLG 283 +K F+ GG + ++ + PI+ +K+ +Q+ S A+ Y +G Sbjct: 8 LKDFLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQGFL 67 Query: 284 SFYKGLSAGLLR---QATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGA 454 SF++G A ++R A ++ + ++ + G AGA Sbjct: 68 SFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDRHKQFWRYFAGNLASGGAAGATSL 127 Query: 455 CVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 C P D A R+ AD AAQ R + + L +I +G+ L++ Sbjct: 128 CFVYPLDFARTRLAADVGKGAAQ-REFSGLGNCLTKIFKSDGLRGLYQ 174
>UCP4_HUMAN (O95847) Mitochondrial uncoupling protein 4 (UCP 4) (Solute carrier| family 25 member 27) Length = 323 Score = 38.5 bits (88), Expect = 0.015 Identities = 36/175 (20%), Positives = 72/175 (41%), Gaps = 17/175 (9%) Frame = +2 Query: 125 VWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAKTM------------YA 268 +WK++ + G +G++ + P D++KV++Q+ EG K + A Sbjct: 127 LWKSV---IGGMMAGVIGQFLANPTDLVKVQMQM-EGKRKLEGKPLRFRGVHHAFAKILA 182 Query: 269 NEGLGSFYKG-----LSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGL 433 G+ + G A L+ TT ++ N +E N ++ L Sbjct: 183 EGGIRGLWAGWVPNIQRAALVNMGDLTTYDTVKHYLVLNTPLEDN------IMTHGLSSL 236 Query: 434 TAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 +G + + +G+PAD+ R+ + YK++ L + EG ++L+K Sbjct: 237 CSGLVASILGTPADVIKSRIMNQPRDKQGRGLLYKSSTDCLIQAVQGEGFMSLYK 291
>ADT3_PIG (Q6QRN9) ADP/ATP translocase 3 (Adenine nucleotide translocator 2)| (ANT 3) (ADP,ATP carrier protein 3) (Solute carrier family 25 member 6) Length = 297 Score = 38.5 bits (88), Expect = 0.015 Identities = 37/158 (23%), Positives = 60/158 (37%), Gaps = 9/158 (5%) Frame = +2 Query: 152 NGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAK---------TMYANEGLGSFYKGLS 304 +GGA+G + C + P+D + ++ G +A + + ++G+ Y+G + Sbjct: 118 SGGAAGATSLCFVYPLDFARTRLAADVGKSATEREFKGLGDCLVKITKSDGIRGLYQGFN 177 Query: 305 AGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLAL 484 + Y A G + T K + D R +V I T A+ P D Sbjct: 178 VSVQGIIIYRAAYFGVYG--TAKGM-LPDPRNTHIVVSWMIAQTVTAVAGVFSYPFDTVR 234 Query: 485 IRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 RM S A YK +I DEG A +K Sbjct: 235 RRMMMQSGRKGADIM-YKGTLDCWRKIFKDEGGKAFFK 271
>ADT2_RAT (Q09073) ADP/ATP translocase 2 (Adenine nucleotide translocator 2)| (ANT 2) (ADP,ATP carrier protein 2) (Solute carrier family 25 member 5) Length = 297 Score = 38.5 bits (88), Expect = 0.015 Identities = 36/167 (21%), Positives = 65/167 (38%), Gaps = 14/167 (8%) Frame = +2 Query: 140 KPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAKTMY-----------ANEGLGS 286 K F+ GG + ++ + PI+ +K+ +Q+ S A Y +G+ S Sbjct: 9 KDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVLS 68 Query: 287 FYKGLSAGLLR---QATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGAC 457 F++G A ++R A ++ + ++ G AGA C Sbjct: 69 FWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWRYFAGNLASGGAAGATSLC 128 Query: 458 VGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 P D A R+ AD A+ R +K L +I +G+ L++ Sbjct: 129 FVYPLDFARTRLAADVGKAGAE-REFKGLGDCLVKIYKSDGIKGLYQ 174 Score = 33.9 bits (76), Expect = 0.37 Identities = 33/158 (20%), Positives = 57/158 (36%), Gaps = 9/158 (5%) Frame = +2 Query: 152 NGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAK---------TMYANEGLGSFYKGLS 304 +GGA+G + C + P+D + ++ G A + +Y ++G+ Y+G + Sbjct: 118 SGGAAGATSLCFVYPLDFARTRLAADVGKAGAEREFKGLGDCLVKIYKSDGIKGLYQGFN 177 Query: 305 AGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLAL 484 + Y A G + T K + D + + I + A+ P D Sbjct: 178 VSVQGIIIYRAAYFGIYD--TAKGM-LPDPKNTHIFISWMIAQSVTAVAGLTSYPFDTVR 234 Query: 485 IRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 RM S Y +I DEG A +K Sbjct: 235 RRMMMQSGRKGTDIM-YTGTLDCWRKIARDEGGKAFFK 271
>ADT2_MOUSE (P51881) ADP/ATP translocase 2 (Adenine nucleotide translocator 2)| (ANT 2) (ADP,ATP carrier protein 2) (Solute carrier family 25 member 5) Length = 297 Score = 38.5 bits (88), Expect = 0.015 Identities = 36/167 (21%), Positives = 65/167 (38%), Gaps = 14/167 (8%) Frame = +2 Query: 140 KPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAKTMY-----------ANEGLGS 286 K F+ GG + ++ + PI+ +K+ +Q+ S A Y +G+ S Sbjct: 9 KDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVLS 68 Query: 287 FYKGLSAGLLR---QATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGAC 457 F++G A ++R A ++ + ++ G AGA C Sbjct: 69 FWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWRYFAGNLASGGAAGATSLC 128 Query: 458 VGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 P D A R+ AD A+ R +K L +I +G+ L++ Sbjct: 129 FVYPLDFARTRLAADVGKAGAE-REFKGLGDCLVKIYKSDGIKGLYQ 174 Score = 34.3 bits (77), Expect = 0.28 Identities = 33/158 (20%), Positives = 57/158 (36%), Gaps = 9/158 (5%) Frame = +2 Query: 152 NGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAK---------TMYANEGLGSFYKGLS 304 +GGA+G + C + P+D + ++ G A + +Y ++G+ Y+G + Sbjct: 118 SGGAAGATSLCFVYPLDFARTRLAADVGKAGAEREFKGLGDCLVKIYKSDGIKGLYQGFN 177 Query: 305 AGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLAL 484 + Y A G + T K + D + + I + A+ P D Sbjct: 178 VSVQGIIIYRAAYFGIYD--TAKGM-LPDPKNTHIFISWMIAQSVTAVAGLTSYPFDTVR 234 Query: 485 IRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 RM S Y +I DEG A +K Sbjct: 235 RRMMMQSGRKGTDIM-YTGTLDCWRKIARDEGSKAFFK 271
>GHC2_RAT (Q505J6) Mitochondrial glutamate carrier 2 (GC-2) (Glutamate/H(+)| symporter 2) (Solute carrier family 25 member 18) Length = 315 Score = 38.5 bits (88), Expect = 0.015 Identities = 31/132 (23%), Positives = 54/132 (40%), Gaps = 6/132 (4%) Frame = +2 Query: 149 VNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQ------VAKTMYANEGLGSFYKGLSAG 310 +NGG +G++ + PID+ K ++Q +G + KT A EG Y+G + Sbjct: 13 INGGIAGLVGVTCVFPIDLAKTRLQNQQGKDVYKGMTDCLVKTARA-EGFLGMYRGAAVN 71 Query: 311 LLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLALIR 490 L +L + L + + DG L + G AG + P ++ I+ Sbjct: 72 LTLVTPEKAIKLAANDFL--RQLLMQDGTQRNLKMEMLAGCGAGICQVVITCPMEMLKIQ 129 Query: 491 MQADSTLPAAQR 526 +Q L Q+ Sbjct: 130 LQDAGRLAVCQQ 141 Score = 35.8 bits (81), Expect = 0.097 Identities = 23/87 (26%), Positives = 36/87 (41%) Frame = +2 Query: 236 SAAQVAKTMYANEGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQ 415 SA +A + +GL Y+GL A LLR ++ F L + G+ Sbjct: 165 SATLIAWELLRTQGLSGLYRGLGATLLRDIPFSIIYFPLFANLNQLGVSELTGK-ASFTH 223 Query: 416 KAFIGLTAGAIGACVGSPADLALIRMQ 496 G AG++ A +P D+ R+Q Sbjct: 224 SFVAGCAAGSVSAVAVTPLDVLKTRIQ 250
>GHC2_HUMAN (Q9H1K4) Mitochondrial glutamate carrier 2 (GC-2) (Glutamate/H(+)| symporter 2) (Solute carrier family 25 member 18) Length = 315 Score = 38.5 bits (88), Expect = 0.015 Identities = 31/122 (25%), Positives = 50/122 (40%), Gaps = 6/122 (4%) Frame = +2 Query: 149 VNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQ------VAKTMYANEGLGSFYKGLSAG 310 +NGG +G++ + PID+ K ++Q G A + KT A EG Y+G + Sbjct: 13 INGGVAGLVGVTCVFPIDLAKTRLQNQHGKAMYKGMIDCLMKTARA-EGFFGMYRGAAVN 71 Query: 311 LLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLALIR 490 L +L + +E DG L + G AG V P ++ I+ Sbjct: 72 LTLVTPEKAIKLAANDFFRRLLME--DGMQRNLKMEMLAGCGAGMCQVVVTCPMEMLKIQ 129 Query: 491 MQ 496 +Q Sbjct: 130 LQ 131 Score = 36.6 bits (83), Expect = 0.057 Identities = 25/87 (28%), Positives = 36/87 (41%) Frame = +2 Query: 236 SAAQVAKTMYANEGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQ 415 SA +A + +GL Y+GL A LLR ++ F L N G+ Sbjct: 165 SATLIAWELLRTQGLAGLYRGLGATLLRDIPFSIIYFPLFANLNNLGFNELAGK-ASFAH 223 Query: 416 KAFIGLTAGAIGACVGSPADLALIRMQ 496 G AG+I A +P D+ R+Q Sbjct: 224 SFVSGCVAGSIAAVAVTPLDVLKTRIQ 250
>ADT3_BOVIN (P32007) ADP/ATP translocase 3 (Adenine nucleotide translocator 2)| (ANT 3) (ADP,ATP carrier protein 3) (Solute carrier family 25 member 6) (ADP,ATP carrier protein, isoform T2) (ANT 2) Length = 297 Score = 38.1 bits (87), Expect = 0.020 Identities = 36/158 (22%), Positives = 60/158 (37%), Gaps = 9/158 (5%) Frame = +2 Query: 152 NGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAK---------TMYANEGLGSFYKGLS 304 +GGA+G + C + P+D + ++ G + + + ++G+ Y+G + Sbjct: 118 SGGAAGATSLCFVYPLDFARTRLAADVGKSGSEREFRGLGDCLVKITKSDGIRGLYQGFN 177 Query: 305 AGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLAL 484 + Y A G + T K + D + +V I T A+ V P D Sbjct: 178 VSVQGIIIYRAAYFGIYD--TAKGM-LPDPKNTHIVVSWMIAQTVTAVAGVVSYPFDTVR 234 Query: 485 IRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 RM S A YK +I DEG A +K Sbjct: 235 RRMMMQSGRKGADIM-YKGTVDCWRKILKDEGGKAFFK 271
>ADT1_BOVIN (P02722) ADP/ATP translocase 1 (Adenine nucleotide translocator 1)| (ANT 1) (ADP,ATP carrier protein 1) (Solute carrier family 25 member 4) (ADP,ATP carrier protein, heart isoform T1) Length = 297 Score = 38.1 bits (87), Expect = 0.020 Identities = 36/168 (21%), Positives = 68/168 (40%), Gaps = 14/168 (8%) Frame = +2 Query: 137 IKPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAKTMY-----------ANEGLG 283 +K F+ GG + ++ + PI+ +K+ +Q+ S A+ Y +G Sbjct: 8 LKDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQGFL 67 Query: 284 SFYKGLSAGLLR---QATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGA 454 SF++G A ++R A ++ + ++ + G AGA Sbjct: 68 SFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDRHKQFWRYFAGNLASGGAAGATSL 127 Query: 455 CVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 C P D A R+ AD AAQ R + + + +I +G+ L++ Sbjct: 128 CFVYPLDFARTRLAADVGKGAAQ-REFTGLGNCITKIFKSDGLRGLYQ 174
>MFRN2_MOUSE (Q8R0Z5) Mitoferrin-2 (Mitochondrial iron transporter 2) (Solute| carrier family 25 member 28) (Mitochondrial RNA splicing protein 3/4 homolog) (MRS3/4) Length = 364 Score = 38.1 bits (87), Expect = 0.020 Identities = 33/151 (21%), Positives = 63/151 (41%), Gaps = 12/151 (7%) Frame = +2 Query: 149 VNGGASGMLATCV----IQPIDMIKVKIQLGEGSAAQVA---KTMYANEGLGSFYKGLSA 307 + GA+G +AT + + P +++K ++Q+ +V + ++ NEG G+FY+ + Sbjct: 171 IANGAAGCVATLLHDAAMNPAEVVKQRMQMYNSPYHRVTDCVRAVWQNEGAGAFYRSYTT 230 Query: 308 GLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADL--A 481 L + ++ L N R G AGA+ A +P D+ Sbjct: 231 QLTMNVPFQAIHFMTYEFLQE---HFNPQRRYNPSSHVLCGACAGAVAAAATTPLDVCKT 287 Query: 482 LIRMQADSTLPAAQRRH---YKNAFHALYRI 565 L+ Q L + H +AF +Y++ Sbjct: 288 LLNTQESLALNSNITGHITGMASAFRTVYQV 318 Score = 36.2 bits (82), Expect = 0.074 Identities = 23/57 (40%), Positives = 29/57 (50%) Frame = +2 Query: 428 GLTAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 G AG + CV P D RMQ+ PAA+ Y+N AL+RI EG LW+ Sbjct: 79 GAVAGILEHCVMYPIDCVKTRMQSLQPDPAAR---YRNVLEALWRIMRTEG---LWR 129 Score = 30.0 bits (66), Expect = 5.3 Identities = 24/72 (33%), Positives = 34/72 (47%), Gaps = 7/72 (9%) Frame = +2 Query: 110 AAPTGVWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQ-LGEGSAAQVAKTMYA------ 268 A P G T V G +G+L CV+ PID +K ++Q L AA+ + A Sbjct: 65 ALPAGATVTTH-MVAGAVAGILEHCVMYPIDCVKTRMQSLQPDPAARYRNVLEALWRIMR 123 Query: 269 NEGLGSFYKGLS 304 EGL +GL+ Sbjct: 124 TEGLWRPMRGLN 135
>MFRN_CAEEL (Q23125) Mitoferrin| Length = 312 Score = 38.1 bits (87), Expect = 0.020 Identities = 32/133 (24%), Positives = 57/133 (42%), Gaps = 10/133 (7%) Frame = +2 Query: 158 GASGMLAT----CVIQPIDMIKVKIQLG---EGSAAQVAKTMYANEGLGSFYKGLSAGLL 316 GASG++AT ++ P +++K ++Q+ GS+ + A+ +Y EG+ +FY+ + L Sbjct: 118 GASGVVATLIHDAIMNPAEVVKQRMQMAFSPYGSSLECARCVYNREGVAAFYRSYTTQLA 177 Query: 317 RQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPAD---LALI 487 + S+ + N G AG + A + +P D L Sbjct: 178 MNVPFQAIHFMSYEFWQH---VLNPEHKYDPKSHLIAGGLAGGLAAALTTPMDCVKTVLN 234 Query: 488 RMQADSTLPAAQR 526 QA PA +R Sbjct: 235 TQQAAEADPANRR 247
>ADT2_PONPY (Q5R5A1) ADP/ATP translocase 2 (Adenine nucleotide translocator 2)| (ANT 2) (ADP,ATP carrier protein 2) (Solute carrier family 25 member 5) Length = 297 Score = 37.7 bits (86), Expect = 0.026 Identities = 35/167 (20%), Positives = 65/167 (38%), Gaps = 14/167 (8%) Frame = +2 Query: 140 KPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAKTMY-----------ANEGLGS 286 K F+ GG + ++ + PI+ +K+ +Q+ S A Y +G+ S Sbjct: 9 KDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVLS 68 Query: 287 FYKGLSAGLLRQ---ATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGAC 457 F++G A ++R A ++ + ++ G AGA C Sbjct: 69 FWRGNLANVIRHFPTQALNFAFKDKYKQIFLGGVDKRTQFWRYFAGNLASGGAAGATSLC 128 Query: 458 VGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 P D A R+ AD A+ R ++ L +I +G+ L++ Sbjct: 129 FVYPLDFARTRLAADVGKAGAE-REFRGLGDCLVKIYKSDGIKGLYQ 174 Score = 37.4 bits (85), Expect = 0.033 Identities = 35/158 (22%), Positives = 58/158 (36%), Gaps = 9/158 (5%) Frame = +2 Query: 152 NGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAK---------TMYANEGLGSFYKGLS 304 +GGA+G + C + P+D + ++ G A + +Y ++G+ Y+G + Sbjct: 118 SGGAAGATSLCFVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFN 177 Query: 305 AGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLAL 484 + Y A G + T K + D + +V I T A+ P D Sbjct: 178 VSVQGIIIYRAAYFGIYD--TAKGM-LPDPKNTHIVISWMIAQTVTAVAGLTSYPFDTVR 234 Query: 485 IRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 RM S Y +I DEG A +K Sbjct: 235 RRMMMQSGRKGTDIM-YTGTLDCWRKIARDEGGKAFFK 271
>MFRN2_HUMAN (Q96A46) Mitoferrin-2 (Mitochondrial iron transporter 2) (Solute| carrier family 25 member 28) (Mitochondrial RNA splicing protein 3/4 homolog) (MRS3/4) (hMRS3/4) Length = 364 Score = 37.7 bits (86), Expect = 0.026 Identities = 33/151 (21%), Positives = 63/151 (41%), Gaps = 12/151 (7%) Frame = +2 Query: 149 VNGGASGMLATCV----IQPIDMIKVKIQLGEGSAAQVA---KTMYANEGLGSFYKGLSA 307 + GA+G +AT + + P +++K ++Q+ +V + ++ NEG G+FY+ + Sbjct: 171 IANGAAGCVATLLHDAAMNPAEVVKQRMQMYNSPYHRVTDCVRAVWQNEGAGAFYRSYTT 230 Query: 308 GLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADL--A 481 L + ++ L N R G AGA+ A +P D+ Sbjct: 231 QLTMNVPFQAIHFMTYEFLQE---HFNPQRRYNPSSHVLSGACAGAVAAAATTPLDVCKT 287 Query: 482 LIRMQADSTLPAAQRRH---YKNAFHALYRI 565 L+ Q L + H +AF +Y++ Sbjct: 288 LLNTQESLALNSHITGHITGMASAFRTVYQV 318 Score = 36.2 bits (82), Expect = 0.074 Identities = 23/57 (40%), Positives = 29/57 (50%) Frame = +2 Query: 428 GLTAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 G AG + CV P D RMQ+ PAA+ Y+N AL+RI EG LW+ Sbjct: 79 GAVAGILEHCVMYPIDCVKTRMQSLQPDPAAR---YRNVLEALWRIIRTEG---LWR 129 Score = 30.8 bits (68), Expect = 3.1 Identities = 25/79 (31%), Positives = 36/79 (45%), Gaps = 7/79 (8%) Frame = +2 Query: 89 DAKQQQAAAPTGVWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQ-LGEGSAAQVAKTMY 265 D+ A P G T V G +G+L CV+ PID +K ++Q L AA+ + Sbjct: 58 DSGPDYEALPAGATVTTH-MVAGAVAGILEHCVMYPIDCVKTRMQSLQPDPAARYRNVLE 116 Query: 266 A------NEGLGSFYKGLS 304 A EGL +GL+ Sbjct: 117 ALWRIIRTEGLWRPMRGLN 135
>PM34_MOUSE (O70579) Peroxisomal membrane protein PMP34 (34 kDa peroxisomal| membrane protein) (Solute carrier family 25 member 17) Length = 307 Score = 37.7 bits (86), Expect = 0.026 Identities = 39/164 (23%), Positives = 70/164 (42%), Gaps = 15/164 (9%) Frame = +2 Query: 149 VNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQ----VAKTMYANEGLGSFYKG----LS 304 V G + A V P+D ++++Q+ E ++ V + EGL + Y+G +S Sbjct: 14 VAGAVGSVTAMTVFFPLDTARLRLQVDEKRKSKTTHAVLLEIIKEEGLLAPYRGWFPVIS 73 Query: 305 AGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLAL 484 + Y S + + K ++ G+ L +G AG + + +P + Sbjct: 74 SLCCSNFVYFYT-FNSLKAVWVKGQRSSTGKDL------VVGFVAGVVNVLLTTPLWVVN 126 Query: 485 IRMQADSTLPAAQRRH-------YKNAFHALYRITADEGVLALW 595 R++ L A+ R+ YK A ++I DEG+LALW Sbjct: 127 TRLK----LQGAKFRNEDIIPTNYKGIIDAFHQIIRDEGILALW 166
>ADT_NEUCR (P02723) ADP,ATP carrier protein (ADP/ATP translocase) (Adenine| nucleotide translocator) (ANT) Length = 313 Score = 37.4 bits (85), Expect = 0.033 Identities = 39/175 (22%), Positives = 72/175 (41%), Gaps = 16/175 (9%) Frame = +2 Query: 122 GVWKTIKP-FVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQ-----------VAKTMY 265 G WK + +GGA+G + + +D + ++ SA + V + Sbjct: 113 GYWKWMAGNLASGGAAGATSLLFVYSLDYARTRLANDAKSAKKGGERQFNGLVDVYRKTI 172 Query: 266 ANEGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAG- 442 A++G+ Y+G + Y G + + +P+ LV A Sbjct: 173 ASDGIAGLYRGFGPSVAGIVVYRGLYFGLYDSI----------KPVLLVGDLKNNFLASF 222 Query: 443 AIGACVGSPADLA---LIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 A+G CV + A +A L ++ + + + YK++F A +I A EGV +L+K Sbjct: 223 ALGWCVTTAAGIASYPLDTIRRRMMMTSGEAVKYKSSFDAASQIVAKEGVKSLFK 277 Score = 35.4 bits (80), Expect = 0.13 Identities = 20/67 (29%), Positives = 30/67 (44%), Gaps = 2/67 (2%) Frame = +2 Query: 404 PLVQKAFIGLTAGAIGACVGSPADLALIRMQADSTLPAAQR--RHYKNAFHALYRITADE 577 P V +G + A+ +P + + +Q + A R R Y R TADE Sbjct: 12 PFVADFLMGGVSAAVSKTAAAPIERIKLLVQNQDEMIRAGRLDRRYNGIIDCFKRTTADE 71 Query: 578 GVLALWK 598 GV+ALW+ Sbjct: 72 GVMALWR 78 Score = 31.2 bits (69), Expect = 2.4 Identities = 25/86 (29%), Positives = 39/86 (45%), Gaps = 20/86 (23%) Frame = +2 Query: 122 GVWKTIKPFVNGG-------ASGMLATCVIQ-------PIDMIKVKIQLGEGSAAQ---- 247 G++ +IKP + G AS L CV P+D I+ ++ + G A + Sbjct: 200 GLYDSIKPVLLVGDLKNNFLASFALGWCVTTAAGIASYPLDTIRRRMMMTSGEAVKYKSS 259 Query: 248 --VAKTMYANEGLGSFYKGLSAGLLR 319 A + A EG+ S +KG A +LR Sbjct: 260 FDAASQIVAKEGVKSLFKGAGANILR 285
>ADT2_HUMAN (P05141) ADP/ATP translocase 2 (Adenine nucleotide translocator 2)| (ANT 2) (ADP,ATP carrier protein 2) (Solute carrier family 25 member 5) (ADP,ATP carrier protein, fibroblast isoform) Length = 297 Score = 37.4 bits (85), Expect = 0.033 Identities = 35/158 (22%), Positives = 58/158 (36%), Gaps = 9/158 (5%) Frame = +2 Query: 152 NGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAK---------TMYANEGLGSFYKGLS 304 +GGA+G + C + P+D + ++ G A + +Y ++G+ Y+G + Sbjct: 118 SGGAAGATSLCFVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFN 177 Query: 305 AGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLAL 484 + Y A G + T K + D + +V I T A+ P D Sbjct: 178 VSVQGIIIYRAAYFGIYD--TAKGM-LPDPKNTHIVISWMIAQTVTAVAGLTSYPFDTVR 234 Query: 485 IRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 RM S Y +I DEG A +K Sbjct: 235 RRMMMQSGRKGTDIM-YTGTLDCWRKIARDEGGKAFFK 271 Score = 37.4 bits (85), Expect = 0.033 Identities = 35/167 (20%), Positives = 65/167 (38%), Gaps = 14/167 (8%) Frame = +2 Query: 140 KPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAKTMY-----------ANEGLGS 286 K F+ GG + ++ + PI+ +K+ +Q+ S A Y +G+ S Sbjct: 9 KDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVLS 68 Query: 287 FYKGLSAGLLR---QATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGAC 457 F++G A ++R A ++ + ++ G AGA C Sbjct: 69 FWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWRYFAGNLASGGAAGATSLC 128 Query: 458 VGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 P D A R+ AD A+ R ++ L +I +G+ L++ Sbjct: 129 FVYPLDFARTRLAADVGKAGAE-REFRGLGDCLVKIYKSDGIKGLYQ 174
>ADT2_BOVIN (Q8SQH5) ADP/ATP translocase 2 (Adenine nucleotide translocator 2)| (ANT 2) (ADP,ATP carrier protein 2) (Solute carrier family 25 member 5) Length = 297 Score = 37.4 bits (85), Expect = 0.033 Identities = 35/167 (20%), Positives = 65/167 (38%), Gaps = 14/167 (8%) Frame = +2 Query: 140 KPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAKTMY-----------ANEGLGS 286 K F+ GG + ++ + PI+ +K+ +Q+ S A Y +G+ S Sbjct: 9 KDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVLS 68 Query: 287 FYKGLSAGLLR---QATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGAC 457 F++G A ++R A ++ + ++ G AGA C Sbjct: 69 FWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWRYFAGNLASGGAAGATSLC 128 Query: 458 VGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 P D A R+ AD A+ R ++ L +I +G+ L++ Sbjct: 129 FVYPLDFARTRLAADVGKAGAE-REFRGLGDCLVKIYKSDGIRGLYQ 174 Score = 35.0 bits (79), Expect = 0.17 Identities = 33/158 (20%), Positives = 57/158 (36%), Gaps = 9/158 (5%) Frame = +2 Query: 152 NGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAK---------TMYANEGLGSFYKGLS 304 +GGA+G + C + P+D + ++ G A + +Y ++G+ Y+G + Sbjct: 118 SGGAAGATSLCFVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIRGLYQGFN 177 Query: 305 AGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLAL 484 + Y A G + T K + D + + I + A+ P D Sbjct: 178 VSVQGIIIYRAAYFGIYD--TAKGM-LPDPKNTHIFISWMIAQSVTAVAGLTSYPFDTVR 234 Query: 485 IRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 RM S Y +I DEG A +K Sbjct: 235 RRMMMQSGRKGTDIM-YTGTLDCWRKIARDEGAKAFFK 271
>TXTP_YEAST (P38152) Tricarboxylate transport protein (Citrate transport| protein) (CTP) Length = 299 Score = 37.4 bits (85), Expect = 0.033 Identities = 38/176 (21%), Positives = 68/176 (38%), Gaps = 16/176 (9%) Frame = +2 Query: 119 TGVWKTIKPFVNGGASGML-ATCVIQPIDMIKVKIQLGEGSAA-----------QVAKTM 262 TG + + G +G+L + + P + IK + + SA + ++ Sbjct: 103 TGELSGTRGVIAGLGAGLLESVAAVTPFEAIKTALIDDKQSATPKYHNNGRGVVRNYSSL 162 Query: 263 YANEGLGSFYKGLSAGLLRQATYTTARLGSF---RVLTNKAIEANDGRPLPLVQKAFIGL 433 ++G Y+G+ +RQA RLG + + L ++ +PL +G Sbjct: 163 VRDKGFSGLYRGVLPVSMRQAANQAVRLGCYNKIKTLIQDYTDSPKDKPLSSGLTFLVGA 222 Query: 434 TAGAIGACVGSPADLALIRMQA-DSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 +G + P D RMQ+ DST Y + + I +EG+ WK Sbjct: 223 FSGIVTVYSTMPLDTVKTRMQSLDST-------KYSSTMNCFATIFKEEGLKTFWK 271 Score = 30.8 bits (68), Expect = 3.1 Identities = 18/62 (29%), Positives = 31/62 (50%), Gaps = 4/62 (6%) Frame = +2 Query: 146 FVNGGASGMLATCVIQPIDMIKVKIQLGEG----SAAQVAKTMYANEGLGSFYKGLSAGL 313 F+ G SG++ P+D +K ++Q + S T++ EGL +F+KG + L Sbjct: 218 FLVGAFSGIVTVYSTMPLDTVKTRMQSLDSTKYSSTMNCFATIFKEEGLKTFWKGATPRL 277 Query: 314 LR 319 R Sbjct: 278 GR 279
>YIA6_YEAST (P40556) Putative mitochondrial carrier YIL006W| Length = 373 Score = 37.0 bits (84), Expect = 0.044 Identities = 22/77 (28%), Positives = 35/77 (45%), Gaps = 7/77 (9%) Frame = +2 Query: 164 SGMLATCVIQPIDMIKVKIQLGEGSAAQVA-------KTMYANEGLGSFYKGLSAGLLRQ 322 S M+A+ V P ++++ ++QL + K YA EGL FY G + L+R Sbjct: 288 SKMIASAVTYPHEILRTRMQLKSDIPDSIQRRLFPLIKATYAQEGLKGFYSGFTTNLVRT 347 Query: 323 ATYTTARLGSFRVLTNK 373 + L SF N+ Sbjct: 348 IPASAITLVSFEYFRNR 364 Score = 31.2 bits (69), Expect = 2.4 Identities = 18/60 (30%), Positives = 25/60 (41%) Frame = +2 Query: 419 AFIGLTAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 A G AG + P D+A R+QA + +Y+ L I DEG L+K Sbjct: 81 ALSGAFAGFLSGVAVCPLDVAKTRLQAQGLQTRFENPYYRGIMGTLSTIVRDEGPRGLYK 140
>MPCP_YEAST (P23641) Mitochondrial phosphate carrier protein (Phosphate| transport protein) (PTP) (mPic 1) (Mitochondrial import receptor) (p32) Length = 311 Score = 37.0 bits (84), Expect = 0.044 Identities = 32/127 (25%), Positives = 52/127 (40%), Gaps = 13/127 (10%) Frame = +2 Query: 173 LATCVIQPIDMIKVKI----QLGEGSAAQVAKTMYANEGLGSFYKGLSAGLLRQATYTTA 340 LA + P++ ++++ Q G ++ + EG+GSFY G + L +Q Y A Sbjct: 128 LADIALCPLEATRIRLVSQPQFANGLVGGFSRIL-KEEGIGSFYSGFTPILFKQIPYNIA 186 Query: 341 RLGSFRVLTNKAIEANDGRPLP---------LVQKAFIGLTAGAIGACVGSPADLALIRM 493 + ++ +A E G P + GLTAG A V PAD L ++ Sbjct: 187 KF----LVFERASEFYYGFAGPKEKLSSTSTTLLNLLSGLTAGLAAAIVSQPADTLLSKV 242 Query: 494 QADSTLP 514 P Sbjct: 243 NKTKKAP 249 Score = 32.7 bits (73), Expect = 0.82 Identities = 38/152 (25%), Positives = 62/152 (40%), Gaps = 6/152 (3%) Frame = +2 Query: 146 FVNGGASGMLAT-CVIQPIDMIKVKIQL-----GEGSAAQVAKTMYANEGLGSFYKGLSA 307 F GA G +T + PID++K +IQL +G K + A EG G+ G Sbjct: 20 FALAGAIGCGSTHSSMVPIDVVKTRIQLEPTVYNKGMVGSF-KQIIAGEGAGALLTGFGP 78 Query: 308 GLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLALI 487 LL + + G + V I+ N G K + + + A+ + AD+AL Sbjct: 79 TLLGYSIQGAFKFGGYEVFKKFFID-NLGYDTASRYKNSVYMGSAAMAEFL---ADIALC 134 Query: 488 RMQADSTLPAAQRRHYKNAFHALYRITADEGV 583 ++A +Q + RI +EG+ Sbjct: 135 PLEATRIRLVSQPQFANGLVGGFSRILKEEGI 166
>ADT_CHLKE (P31692) ADP,ATP carrier protein (ADP/ATP translocase) (Adenine| nucleotide translocator) (ANT) Length = 339 Score = 36.6 bits (83), Expect = 0.057 Identities = 38/170 (22%), Positives = 75/170 (44%), Gaps = 16/170 (9%) Frame = +2 Query: 137 IKPFVNGGASGMLATCVIQPIDMIKVKIQLGEGS----AAQVAK---------TMYANEG 277 +K + GG +G ++ + PI+ +K+ +Q + + + QV + + + +G Sbjct: 42 VKDLLAGGTAGAISKTAVAPIERVKLLLQTQDSNPMIKSGQVPRYTGIVNCFVRVSSEQG 101 Query: 278 LGSFYKGLSAGLLR---QATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAI 448 + SF++G A ++R + A + + L K D +V A GL AGA Sbjct: 102 VASFWRGNLANVVRYFPTQAFNFAFKDTIKGLFPKYSPKTDFWRFFVVNLASGGL-AGAG 160 Query: 449 GACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 + P D A R+ AD + + + R + L ++ G +AL++ Sbjct: 161 SLLIVYPLDFARTRLAAD--VGSGKSREFTGLVDCLSKVVKRGGPMALYQ 208
>MFRN1_BRARE (Q287T7) Mitoferrin-1 (Mitochondrial iron transporter 1) (Solute| carrier family 25 member 37) (Protein frascati) Length = 332 Score = 36.6 bits (83), Expect = 0.057 Identities = 36/156 (23%), Positives = 62/156 (39%), Gaps = 6/156 (3%) Frame = +2 Query: 149 VNGGASGMLATCVIQPIDMIKVKIQLGEG---SAAQVAKTMYANEGLGSFYKGLSAGLLR 319 V G + +L V+ P +++K ++Q+ S + EGL +FY+ S L Sbjct: 136 VAGSVATVLHDAVMNPAEVVKQRMQMYNSPYRSLYDCVLMVSRKEGLAAFYRSYSTQLTM 195 Query: 320 QATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADL--ALIRM 493 + ++ + RP + G AGA+ A V +P D+ L+ Sbjct: 196 NIPFQAVHFITYEFMQEHFNPHRQYRPETHI---ISGAAAGAVSAAVTTPLDVCKTLLNT 252 Query: 494 QADSTLPAAQ-RRHYKNAFHALYRITADEGVLALWK 598 Q + L +A H +AL + GV A +K Sbjct: 253 QENVALSSAHVSGHLSGMVNALRTVYRLGGVPAFFK 288 Score = 32.0 bits (71), Expect = 1.4 Identities = 19/75 (25%), Positives = 35/75 (46%), Gaps = 13/75 (17%) Frame = +2 Query: 149 VNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVA-------------KTMYANEGLGSF 289 ++G A+G ++ V P+D+ K + E A A +T+Y G+ +F Sbjct: 227 ISGAAAGAVSAAVTTPLDVCKTLLNTQENVALSSAHVSGHLSGMVNALRTVYRLGGVPAF 286 Query: 290 YKGLSAGLLRQATYT 334 +KG+ A ++ Q T Sbjct: 287 FKGIQARVIYQMPST 301 Score = 30.0 bits (66), Expect = 5.3 Identities = 20/53 (37%), Positives = 26/53 (49%) Frame = +2 Query: 428 GLTAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVL 586 G AG + V P D RMQ+ P AQ Y++ + AL RI EG+L Sbjct: 40 GAVAGILEHTVMYPVDSVKTRMQSLQPDPKAQ---YRSVYGALKRIVRTEGLL 89
>ADT2_ANOGA (Q7PQV7) ADP,ATP carrier protein 2 (ADP/ATP translocase 2) (Adenine| nucleotide translocator 2) (ANT 2) Length = 300 Score = 36.6 bits (83), Expect = 0.057 Identities = 36/158 (22%), Positives = 59/158 (37%), Gaps = 9/158 (5%) Frame = +2 Query: 152 NGGASGMLATCVIQPIDMIKVKI--QLGEGSAAQVAK-------TMYANEGLGSFYKGLS 304 +GG +G + C + P+D + ++ +G+G+ A+ K ++ +GL Y+G Sbjct: 121 SGGMAGATSLCFVYPLDFARTRLAADVGKGAEAREFKGLGDCISKIFKTDGLVGLYRGFG 180 Query: 305 AGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLAL 484 + Y A G + T + + N + P I + V P D Sbjct: 181 VSVQGIIIYRAAYFGFYD--TARGMLPNP-KTTPWYVSWAIAQCVTTVAGIVSYPFDTVR 237 Query: 485 IRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 RM S A YK H I EG A +K Sbjct: 238 RRMMMQSG-RAKSEIVYKGTLHCWATIAKQEGTGAFFK 274
>ADT3_HUMAN (P12236) ADP/ATP translocase 3 (Adenine nucleotide translocator 2)| (ANT 3) (ADP,ATP carrier protein 3) (Solute carrier family 25 member 6) (ADP,ATP carrier protein, isoform T2) Length = 297 Score = 36.2 bits (82), Expect = 0.074 Identities = 36/158 (22%), Positives = 59/158 (37%), Gaps = 9/158 (5%) Frame = +2 Query: 152 NGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAK---------TMYANEGLGSFYKGLS 304 +GGA+G + C + P+D + ++ G + + + ++G+ Y+G S Sbjct: 118 SGGAAGATSLCFVYPLDFARTRLAADVGKSGTEREFRGLGDCLVKITKSDGIRGLYQGFS 177 Query: 305 AGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLAL 484 + Y A G + T K + D + +V I T A+ V P D Sbjct: 178 VSVQGIIIYRAAYFGVYD--TAKGM-LPDPKNTHIVVSWMIAQTVTAVAGVVSYPFDTVR 234 Query: 485 IRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 RM S A Y +I DEG A +K Sbjct: 235 RRMMMQSGRKGADIM-YTGTVDCWRKIFRDEGGKAFFK 271
>PM34_HUMAN (O43808) Peroxisomal membrane protein PMP34 (34 kDa peroxisomal| membrane protein) (Solute carrier family 25 member 17) Length = 307 Score = 36.2 bits (82), Expect = 0.074 Identities = 39/164 (23%), Positives = 68/164 (41%), Gaps = 15/164 (9%) Frame = +2 Query: 149 VNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQ----VAKTMYANEGLGSFYKG----LS 304 V G + A V P+D ++++Q+ E ++ V + EGL + Y+G +S Sbjct: 14 VAGAVGSVTAMTVFFPLDTARLRLQVDEKRKSKTTHMVLLEIIKEEGLLAPYRGWFPVIS 73 Query: 305 AGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLAL 484 + Y S + L K + G+ L +G AG + + +P + Sbjct: 74 SLCCSNFVYFYT-FNSLKALWVKGQHSTTGKDL------VVGFVAGVVNVLLTTPLWVVN 126 Query: 485 IRMQADSTLPAAQRRH-------YKNAFHALYRITADEGVLALW 595 R++ L A+ R+ YK A ++I DEG+ ALW Sbjct: 127 TRLK----LQGAKFRNEDIVPTNYKGIIDAFHQIIRDEGISALW 166
>YE08_SCHPO (O13805) Putative mitochondrial carrier C17H9.08| Length = 326 Score = 35.0 bits (79), Expect = 0.17 Identities = 29/129 (22%), Positives = 51/129 (39%), Gaps = 10/129 (7%) Frame = +2 Query: 137 IKPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVA----------KTMYANEGLGS 286 +K + GG +G +A V+ P+D +K+ Q S A K +Y GL Sbjct: 18 VKSGIAGGTAGCVAKSVVAPLDRVKILYQTNHASYRGYAYSRHGLYKAIKHIYHVYGLHG 77 Query: 287 FYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGS 466 Y+G +A L R Y + ++ + + + D ++ G AG Sbjct: 78 LYQGHTATLYRVFPYAGIKFVAYEQV--RRVLIRDPEHETHARRFLSGSLAGTCSVFFTY 135 Query: 467 PADLALIRM 493 P +L +R+ Sbjct: 136 PLELIRVRL 144
>ADT1_ANOGA (Q27238) ADP,ATP carrier protein 1 (ADP/ATP translocase 1) (Adenine| nucleotide translocator 1) (ANT 1) Length = 301 Score = 35.0 bits (79), Expect = 0.17 Identities = 37/158 (23%), Positives = 57/158 (36%), Gaps = 9/158 (5%) Frame = +2 Query: 152 NGGASGMLATCVIQPIDMIKVKIQLGEGSAA---------QVAKTMYANEGLGSFYKGLS 304 +GGA+G + C + P+D + ++ G A K ++G+ Y+G + Sbjct: 121 SGGAAGATSLCFVYPLDFARTRLGADVGRGAGEREFNGLLDCLKKTVKSDGIIGLYRGFN 180 Query: 305 AGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLAL 484 + Y A G F T K + + V A + A G + P D Sbjct: 181 VSVQGIIIYRAAYFGCFD--TAKGMLPDPKNTSIFVSWAIAQVVTTASG-IISYPFDTVR 237 Query: 485 IRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 RM S A YKN +I EG A +K Sbjct: 238 RRMMMQSG-RAKSEVMYKNTLDCWVKIGKQEGSGAFFK 274
>MFRN2_BRARE (Q7T292) Mitoferrin-2 (Mitochondrial iron transporter 2) (Solute| carrier family 25 member 28) Length = 376 Score = 34.7 bits (78), Expect = 0.22 Identities = 20/52 (38%), Positives = 27/52 (51%) Frame = +2 Query: 428 GLTAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGV 583 G AG + C+ P D RMQ+ PAA+ Y+N AL+RI EG+ Sbjct: 84 GAVAGIMEHCLMFPIDCVKTRMQSLQPEPAAR---YRNVMDALWRIMRTEGI 132
>YDE9_SCHPO (Q10442) Putative mitochondrial carrier C12B10.09| Length = 345 Score = 34.7 bits (78), Expect = 0.22 Identities = 20/76 (26%), Positives = 39/76 (51%), Gaps = 2/76 (2%) Frame = +2 Query: 149 VNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQV--AKTMYANEGLGSFYKGLSAGLLRQ 322 ++G +G +A + P D++K +I + + V K++ A+EG + YKG+ +L Sbjct: 263 ISGSIAGGIAAALTTPFDVVKTRIMTSQQRLSYVFTIKSIVAHEGFLALYKGIVPRVLWL 322 Query: 323 ATYTTARLGSFRVLTN 370 + LG + V+ N Sbjct: 323 SGGGAIFLGCYDVILN 338
>ADT_KLULA (P49382) ADP,ATP carrier protein (ADP/ATP translocase) (Adenine| nucleotide translocator) (ANT) Length = 305 Score = 34.3 bits (77), Expect = 0.28 Identities = 39/167 (23%), Positives = 67/167 (40%), Gaps = 16/167 (9%) Frame = +2 Query: 146 FVNGGASGMLATCVIQPIDMIKVKIQ-----LGEGSA-------AQVAKTMYANEGLGSF 289 F+ GG S ++ PI+ +K+ IQ + +GS + K A+EG+ SF Sbjct: 14 FLMGGVSAAVSKTAAAPIERVKLLIQNQDEMIKQGSLDRRYTGIVECFKRTAADEGVASF 73 Query: 290 YKGLSAGLLRQATYTTARLG---SFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACV 460 ++G +A ++R + T L ++ + +G G AG + Sbjct: 74 WRGNTANVIRY--FPTQALNFAFKDKIKAMFGFKKEEGYAKWFAGNLASGGLAGGLSLLF 131 Query: 461 GSPADLALIRMQADSTLPAAQRRHYKNAFHALYRIT-ADEGVLALWK 598 D A R+ ADS N +Y+ T A +GV L++ Sbjct: 132 VYSLDYARTRLAADSKSAKKGGERQFNGLVDVYKKTLASDGVAGLYR 178
>MCAT_MOUSE (Q9Z2Z6) Mitochondrial carnitine/acylcarnitine carrier protein| (Carnitine/acylcarnitine translocase) (CAC) (mCAC) (Solute carrier family 25 member 20) Length = 301 Score = 34.3 bits (77), Expect = 0.28 Identities = 40/169 (23%), Positives = 68/169 (40%), Gaps = 23/169 (13%) Frame = +2 Query: 131 KTIKPFVN---GGASGMLATCVIQPIDMIKVKIQ-----------LGEGSAAQVAKTMYA 268 K I PF N GG GM V P+D +KV++Q + G+ KT+ Sbjct: 6 KPISPFKNLLAGGFGGMCLVFVGHPLDTVKVRLQTQPPSLSGQPPMYSGTLDCFRKTL-M 64 Query: 269 NEGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAI 448 EG+ Y+G++A ++ F L K + + L Q G+ +G Sbjct: 65 REGITGLYRGMAAPIIGVTPMFAVCFFGFG-LGKKLQQKSPEDELSYPQLFTAGMLSGVF 123 Query: 449 GACVGSPAD--LALIRMQADS-------TLPAAQRRHYKNAFHALYRIT 568 + +P + L+++QA S TL A++ + + Y+ T Sbjct: 124 TTGIMTPGERIKCLLQIQASSGENKYSGTLDCAKKLYQEFGIRGFYKGT 172 Score = 29.6 bits (65), Expect = 6.9 Identities = 18/62 (29%), Positives = 29/62 (46%), Gaps = 5/62 (8%) Frame = +2 Query: 149 VNGGASGMLATCVIQPIDMIKVKIQLGE-----GSAAQVAKTMYANEGLGSFYKGLSAGL 313 V GG +G+ V P D++K + Q V + + EG+ S YKG +A + Sbjct: 214 VAGGFAGIFNWAVAIPPDVLKSRFQTAPPGKYPNGFRDVLRELIREEGVTSLYKGFNAVM 273 Query: 314 LR 319 +R Sbjct: 274 IR 275
>FLX1_YEAST (P40464) Mitochondrial FAD carrier protein FLX1| Length = 311 Score = 34.3 bits (77), Expect = 0.28 Identities = 17/44 (38%), Positives = 27/44 (61%) Frame = +2 Query: 404 PLVQKAFIGLTAGAIGACVGSPADLALIRMQADSTLPAAQRRHY 535 PL ++ GL+AG++ V P DL +R+Q +T +AQ+ HY Sbjct: 8 PLQKEVISGLSAGSVTTLVVHPLDLLKVRLQLSAT--SAQKAHY 49 Score = 30.8 bits (68), Expect = 3.1 Identities = 16/55 (29%), Positives = 29/55 (52%), Gaps = 5/55 (9%) Frame = +2 Query: 170 MLATCVIQPIDMIKVKIQLGEGSAAQ-----VAKTMYANEGLGSFYKGLSAGLLR 319 M++ ++ P ++K +Q + + + K + AN+G YKGLSA L+R Sbjct: 238 MVSVTLVYPFQLLKSNLQSFRANEQKFRLFPLIKLIIANDGFVGLYKGLSANLVR 292
>ADT1_YEAST (P04710) ADP,ATP carrier protein 1 (ADP/ATP translocase 1) (Adenine| nucleotide translocator 1) (ANT 1) Length = 309 Score = 33.9 bits (76), Expect = 0.37 Identities = 40/167 (23%), Positives = 67/167 (40%), Gaps = 16/167 (9%) Frame = +2 Query: 146 FVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVA------------KTMYANEGLGSF 289 F+ GG S +A PI+ +K+ +Q E Q + K +EG+ SF Sbjct: 17 FLMGGVSAAIAKTGAAPIERVKLLMQNQEEMLKQGSLDTRYKGILDCFKRTATHEGIVSF 76 Query: 290 YKGLSAGLLRQATYTTARLGSFRVLTNKAI---EANDGRPLPLVQKAFIGLTAGAIGACV 460 ++G +A +LR T A +F+ + DG F G AG + Sbjct: 77 WRGNTANVLRYFP-TQALNFAFKDKIKSLLSYDRERDGYAKWFAGNLFSGGAAGGLSLLF 135 Query: 461 GSPADLALIRMQADSTLPAAQRRHYKNAFHALYRIT-ADEGVLALWK 598 D A R+ AD+ + + N +Y+ T +G+L L++ Sbjct: 136 VYSLDYARTRLAADARGSKSTSQRQFNGLLDVYKKTLKTDGLLGLYR 182
>MRS4_YEAST (P23500) Mitochondrial RNA-splicing protein MRS4| Length = 304 Score = 33.1 bits (74), Expect = 0.63 Identities = 21/76 (27%), Positives = 35/76 (46%), Gaps = 1/76 (1%) Frame = +2 Query: 68 ISPEEMADAKQQQAAAPTGVWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAA- 244 ISPE+M + + A ++G + + A ++ P D +K ++QL Sbjct: 110 ISPEDMQTHQPMKTA------------LSGTIATIAADALMNPFDTVKQRLQLDTNLRVW 157 Query: 245 QVAKTMYANEGLGSFY 292 V K +Y NEG +FY Sbjct: 158 NVTKQIYQNEGFAAFY 173
>YHM1_YEAST (P38988) Putative mitochondrial carrier protein YHM1/SHM1| Length = 300 Score = 33.1 bits (74), Expect = 0.63 Identities = 19/61 (31%), Positives = 31/61 (50%), Gaps = 4/61 (6%) Frame = +2 Query: 146 FVNGGASGMLATCVIQPIDMIKVKIQL----GEGSAAQVAKTMYANEGLGSFYKGLSAGL 313 F++ + V P+D+IK +IQ S ++ K NEG+ +F+KGL+ L Sbjct: 214 FISSIVGACSSLIVSAPLDVIKTRIQNRNFDNPESGLRIVKNTLKNEGVTAFFKGLTPKL 273 Query: 314 L 316 L Sbjct: 274 L 274
>ANT1_YEAST (Q06497) Peroxisomal adenine nucleotide transporter 1| Length = 328 Score = 33.1 bits (74), Expect = 0.63 Identities = 19/63 (30%), Positives = 31/63 (49%), Gaps = 3/63 (4%) Frame = +2 Query: 122 GVWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAKTM---YANEGLGSFY 292 G ++ F+ G S M++T V QP+ + K +Q + + Y NEGL S + Sbjct: 218 GSLSAVQNFILGVLSKMISTLVTQPLIVAKAMLQSAGSKFTTFQEALLYLYKNEGLKSLW 277 Query: 293 KGL 301 KG+ Sbjct: 278 KGV 280
>YG5F_YEAST (P53320) Putative mitochondrial carrier YGR257C| Length = 366 Score = 32.7 bits (73), Expect = 0.82 Identities = 20/87 (22%), Positives = 38/87 (43%), Gaps = 12/87 (13%) Frame = +2 Query: 137 IKPFVNGGASGMLATCVIQPIDMIKVKIQLG------------EGSAAQVAKTMYANEGL 280 I F +G SGM+A P D+ K + Q+ + + +T++ EGL Sbjct: 269 INSFASGCISGMIAAICTHPFDVGKTRWQISMMNNSDPKGGNRSRNMFKFLETIWRTEGL 328 Query: 281 GSFYKGLSAGLLRQATYTTARLGSFRV 361 + Y GL+A +++ + S+ + Sbjct: 329 AALYTGLAARVIKIRPSCAIMISSYEI 355
>YAD8_SCHPO (Q09834) Putative mitochondrial carrier C4G8.08| Length = 271 Score = 32.7 bits (73), Expect = 0.82 Identities = 23/71 (32%), Positives = 34/71 (47%), Gaps = 10/71 (14%) Frame = +2 Query: 131 KTIKPFVNGGA-----SGMLATCVIQ----PIDMIKVKIQLGE-GSAAQVAKTMYANEGL 280 + KP V GA GM A V P+++IK + Q+ + GS T+ +EGL Sbjct: 73 RRFKPSVGEGAILYSICGMTAEVVSSFVWTPLEVIKARTQISQKGSVINTISTLARSEGL 132 Query: 281 GSFYKGLSAGL 313 FY+G G+ Sbjct: 133 KGFYRGYWMGV 143
>ADT_CHLRE (P27080) ADP,ATP carrier protein (ADP/ATP translocase) (Adenine| nucleotide translocator) (ANT) Length = 308 Score = 32.3 bits (72), Expect = 1.1 Identities = 24/86 (27%), Positives = 41/86 (47%), Gaps = 20/86 (23%) Frame = +2 Query: 122 GVWKTIKPFVNGG--ASGMLATCVI------------QPIDMIKVKIQLGEGSAAQVAKT 259 G++ ++KP V G A+ LA ++ PID I+ ++ + GSA + + Sbjct: 195 GMYDSLKPVVLVGPLANNFLAAFLLGWGITIGAGLASYPIDTIRRRMMMTSGSAVKYNSS 254 Query: 260 MYA------NEGLGSFYKGLSAGLLR 319 + NEG+ S +KG A +LR Sbjct: 255 FHCFQEIVKNEGMKSLFKGAGANILR 280 Score = 32.0 bits (71), Expect = 1.4 Identities = 35/165 (21%), Positives = 61/165 (36%), Gaps = 16/165 (9%) Frame = +2 Query: 152 NGGASGMLATCVIQPIDMIKVKIQLGEGSAAQ------------VAKTMYANEGLGSFYK 295 +GGA+G ++ + +D + ++ SA + V + A++G+ Y+ Sbjct: 118 SGGAAGAVSLSFVYSLDYARTRLANDAKSAKKGGGDRQFNGLVDVYRKTIASDGIAGLYR 177 Query: 296 GLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAG---AIGACVGS 466 G + + Y G + L + PL G IGA + S Sbjct: 178 GFNISCVGIVVYRGLYFGMYDSLKPVVLVG------PLANNFLAAFLLGWGITIGAGLAS 231 Query: 467 -PADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 598 P D RM S Y ++FH I +EG+ +L+K Sbjct: 232 YPIDTIRRRMMMTS----GSAVKYNSSFHCFQEIVKNEGMKSLFK 272
>MCAT_RAT (P97521) Mitochondrial carnitine/acylcarnitine carrier protein| (Carnitine/acylcarnitine translocase) (CAC) (Solute carrier family 25 member 20) Length = 301 Score = 32.3 bits (72), Expect = 1.1 Identities = 38/170 (22%), Positives = 69/170 (40%), Gaps = 23/170 (13%) Frame = +2 Query: 131 KTIKPFVN---GGASGMLATCVIQPIDMIKVKIQ-----------LGEGSAAQVAKTMYA 268 K I P N GG G+ V P+D +KV++Q + G+ KT++ Sbjct: 6 KPISPLKNLLAGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTIDCFRKTLF- 64 Query: 269 NEGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAI 448 EG+ Y+G++A ++ F L + + + L Q G+ +G Sbjct: 65 REGITGLYRGMAAPIIGVTPMFAVCFFGFG-LGKRLQQKSPEDELTYPQLFTAGMLSGVF 123 Query: 449 GACVGSPAD--LALIRMQADS-------TLPAAQRRHYKNAFHALYRITA 571 + +P + L+++QA S TL A++ + + Y+ TA Sbjct: 124 TTGIMTPGERIKCLLQIQASSGKNKYSGTLDCAKKLYQEFGIRGFYKGTA 173
>ADT3_YEAST (P18238) ADP,ATP carrier protein 3 (ADP/ATP translocase 3) (Adenine| nucleotide translocator 3) (ANT 3) Length = 307 Score = 32.3 bits (72), Expect = 1.1 Identities = 24/86 (27%), Positives = 42/86 (48%), Gaps = 20/86 (23%) Frame = +2 Query: 122 GVWKTIKPFVNGG-------ASGML-------ATCVIQPIDMIKVKIQLGEGSAAQV--- 250 G++ ++KP V G AS +L A+ P+D ++ ++ + G A + Sbjct: 198 GMFDSLKPLVLTGSLDGSFLASFLLGWVVTTGASTCSYPLDTVRRRMMMTSGQAVKYNGA 257 Query: 251 ---AKTMYANEGLGSFYKGLSAGLLR 319 K + A+EG+GS +KG A +LR Sbjct: 258 IDCLKKIVASEGVGSLFKGCGANILR 283 Score = 32.0 bits (71), Expect = 1.4 Identities = 42/187 (22%), Positives = 71/187 (37%), Gaps = 16/187 (8%) Frame = +2 Query: 86 ADAKQQQAAAPTGVWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQ-----LGEGS---- 238 +DAKQQ+ F+ GG S +A PI+ +K+ IQ + +G+ Sbjct: 3 SDAKQQETNFAIN-------FLMGGVSAAIAKTAASPIERVKILIQNQDEMIKQGTLDKK 55 Query: 239 ---AAQVAKTMYANEGLGSFYKGLSAGLLRQATYTTARLG---SFRVLTNKAIEANDGRP 400 K EGL SF++G +A ++R + T L ++ + +G Sbjct: 56 YSGIVDCFKRTAKQEGLISFWRGNTANVIRY--FPTQALNFAFKDKIKLMFGFKKEEGYG 113 Query: 401 LPLVQKAFIGLTAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRIT-ADE 577 G AGA+ D A R+ AD+ N +Y+ T + Sbjct: 114 KWFAGNLASGGAAGALSLLFVYSLDFARTRLAADAKSSKKGGARQFNGLTDVYKKTLKSD 173 Query: 578 GVLALWK 598 G+ L++ Sbjct: 174 GIAGLYR 180
>SUHB_THEMA (O33832) Inositol-1-monophosphatase (EC 3.1.3.25) (IMPase)| (Inositol-1-phosphatase) (I-1-Pase) Length = 256 Score = 32.0 bits (71), Expect = 1.4 Identities = 23/82 (28%), Positives = 37/82 (45%), Gaps = 2/82 (2%) Frame = +2 Query: 215 KIQLGEGSAAQVAKTMYANEGLGSFYKGLSAGLLRQATY--TTARLGSFRVLTNKAIEAN 388 +++LG A + +T+YA EG G+F+ G + A+ GS+ T K IE Sbjct: 105 EVKLGVVHAPALNETLYAEEGSGAFFNGERIRVSENASLEECVGSTGSYVDFTGKFIERM 164 Query: 389 DGRPLPLVQKAFIGLTAGAIGA 454 + R + L A +GA Sbjct: 165 EKRTRRIRILGSAALNAAYVGA 186
>MCAT_HUMAN (O43772) Mitochondrial carnitine/acylcarnitine carrier protein| (Carnitine/acylcarnitine translocase) (CAC) (Solute carrier family 25 member 20) Length = 301 Score = 32.0 bits (71), Expect = 1.4 Identities = 38/169 (22%), Positives = 69/169 (40%), Gaps = 23/169 (13%) Frame = +2 Query: 131 KTIKPFVN---GGASGMLATCVIQPIDMIKVKIQ-----------LGEGSAAQVAKTMYA 268 K I P N GG G+ V P+D +KV++Q + G+ KT++ Sbjct: 6 KPISPLKNLLAGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTFDCFRKTLF- 64 Query: 269 NEGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAI 448 EG+ Y+G++A ++ F L K + + L Q G+ +G Sbjct: 65 REGITGLYRGMAAPIIGVTPMFAVCFFGFG-LGKKLQQKHPEDVLSYPQLFAAGMLSGVF 123 Query: 449 GACVGSPAD--LALIRMQADS-------TLPAAQRRHYKNAFHALYRIT 568 + +P + L+++QA S TL A++ + + +Y+ T Sbjct: 124 TTGIMTPGERIKCLLQIQASSGESKYTGTLDCAKKLYQEFGIRGIYKGT 172 Score = 30.8 bits (68), Expect = 3.1 Identities = 21/76 (27%), Positives = 33/76 (43%), Gaps = 5/76 (6%) Frame = +2 Query: 149 VNGGASGMLATCVIQPIDMIKVKIQLGE-----GSAAQVAKTMYANEGLGSFYKGLSAGL 313 V GG +G+ V P D++K + Q V + + +EG+ S YKG +A + Sbjct: 214 VAGGIAGIFNWAVAIPPDVLKSRFQTAPPGKYPNGFRDVLRELIRDEGVTSLYKGFNAVM 273 Query: 314 LRQATYTTARLGSFRV 361 +R A F V Sbjct: 274 IRAFPANAACFLGFEV 289
>MFN2B_XENLA (Q68F18) Mitoferrin-2B (Mitochondrial iron transporter 2-B) (Solute| carrier family 25 member 28-B) Length = 186 Score = 31.6 bits (70), Expect = 1.8 Identities = 19/51 (37%), Positives = 25/51 (49%) Frame = +2 Query: 428 GLTAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEG 580 G AG + C+ P D RMQ+ PAA+ Y+N AL +I EG Sbjct: 84 GAVAGVMEHCLMYPVDCVKTRMQSLQPDPAAR---YRNVMDALSKIVRTEG 131
>MFN2A_XENLA (Q6GLJ0) Mitoferrin-2A (Mitochondrial iron transporter 2-A) (Solute| carrier family 25 member 28-A) Length = 186 Score = 31.6 bits (70), Expect = 1.8 Identities = 19/51 (37%), Positives = 25/51 (49%) Frame = +2 Query: 428 GLTAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEG 580 G AG + C+ P D RMQ+ PAA+ Y+N AL +I EG Sbjct: 84 GAVAGVMEHCLMYPVDCVKTRMQSLQPDPAAR---YRNVMDALSKIVRTEG 131
>MCAT_MACFA (Q8HXY2) Mitochondrial carnitine/acylcarnitine carrier protein| (Carnitine/acylcarnitine translocase) (CAC) (Solute carrier family 25 member 20) Length = 301 Score = 31.6 bits (70), Expect = 1.8 Identities = 38/169 (22%), Positives = 69/169 (40%), Gaps = 23/169 (13%) Frame = +2 Query: 131 KTIKPFVN---GGASGMLATCVIQPIDMIKVKIQ-----------LGEGSAAQVAKTMYA 268 K I P N GG G+ V P+D +KV++Q + G+ KT++ Sbjct: 6 KPISPLKNLLAGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTFDCFRKTLF- 64 Query: 269 NEGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAI 448 EG+ Y+G++A ++ F L K + + L Q G+ +G Sbjct: 65 REGIRGLYRGMAAPIIGVTPMFAVCFFGFG-LGKKLQQKHPEDVLSYPQLFAAGMLSGIF 123 Query: 449 GACVGSPAD--LALIRMQADS-------TLPAAQRRHYKNAFHALYRIT 568 + +P + L+++QA S TL A++ + + +Y+ T Sbjct: 124 TTGIMTPGERIKCLLQIQASSGETKYTGTLDCAKKLYQEFGIRGIYKGT 172 Score = 30.8 bits (68), Expect = 3.1 Identities = 21/76 (27%), Positives = 33/76 (43%), Gaps = 5/76 (6%) Frame = +2 Query: 149 VNGGASGMLATCVIQPIDMIKVKIQLGE-----GSAAQVAKTMYANEGLGSFYKGLSAGL 313 V GG +G+ V P D++K + Q V + + +EG+ S YKG +A + Sbjct: 214 VAGGIAGIFNWAVAIPPDVLKSRFQTAPPGKYPNGFRDVLRELIPDEGVTSLYKGFNAVM 273 Query: 314 LRQATYTTARLGSFRV 361 +R A F V Sbjct: 274 IRAFPANAACFLGFEV 289
>YHM2_YEAST (Q04013) Mitochondrial DNA replication protein YHM2| Length = 314 Score = 31.6 bits (70), Expect = 1.8 Identities = 31/138 (22%), Positives = 53/138 (38%), Gaps = 17/138 (12%) Frame = +2 Query: 236 SAAQVAKTMYANEGLGSFYKGLSAGLLRQATYTTARLG-------SFRVLTNKAIEANDG 394 S+ V K +Y EG+ KG++A +RQ T +R G R +T K + + Sbjct: 154 SSWSVFKNIYKKEGIRGINKGVNAVAIRQMTNWGSRFGLSRLVEDGIRKITGKTNKDDKL 213 Query: 395 RPLPLVQKAFIGLTAGAIGACVGSPADLALIRMQADSTLPAAQRR----------HYKNA 544 P + + +G G + A P ++ + MQ+ P + + N Sbjct: 214 NPFEKIGASALG---GGLSAW-NQPIEVIRVEMQSKKEDPNRPKNLTVGKTFKYIYQSNG 269 Query: 545 FHALYRITADEGVLALWK 598 LYR L +W+ Sbjct: 270 LKGLYRGVTPRIGLGIWQ 287
>CG69_MOUSE (Q9D8K8) Mitochondrial carrier protein CGI-69 homolog| Length = 359 Score = 31.2 bits (69), Expect = 2.4 Identities = 14/35 (40%), Positives = 21/35 (60%) Frame = +2 Query: 146 FVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQV 250 FV GG SGM+A + P D++K + Q+ G+ V Sbjct: 259 FVAGGISGMVAATLTLPFDVVKTQRQMSLGAVEAV 293
>ADT2_YEAST (P18239) ADP,ATP carrier protein 2 (ADP/ATP translocase 2) (Adenine| nucleotide translocator 2) (ANT 2) Length = 318 Score = 31.2 bits (69), Expect = 2.4 Identities = 42/180 (23%), Positives = 68/180 (37%), Gaps = 16/180 (8%) Frame = +2 Query: 107 AAAPTGVWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQ-----LGEGS-------AAQV 250 A AP + F+ GG S +A PI+ +K+ IQ L +G+ Sbjct: 14 APAPKKESNFLIDFLMGGVSAAVAKTAASPIERVKLLIQNQDEMLKQGTLDRKYAGILDC 73 Query: 251 AKTMYANEGLGSFYKGLSAGLLRQATYTTARLG---SFRVLTNKAIEANDGRPLPLVQKA 421 K EG+ SF++G +A ++R + T L ++ + +G Sbjct: 74 FKRTATQEGVISFWRGNTANVIRY--FPTQALNFAFKDKIKAMFGFKKEEGYAKWFAGNL 131 Query: 422 FIGLTAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRIT-ADEGVLALWK 598 G AGA+ D A R+ ADS N +Y+ T +GV L++ Sbjct: 132 ASGGAAGALSLLFVYSLDYARTRLAADSKSSKKGGARQFNGLIDVYKKTLKSDGVAGLYR 191 Score = 29.3 bits (64), Expect = 9.1 Identities = 14/48 (29%), Positives = 26/48 (54%), Gaps = 6/48 (12%) Frame = +2 Query: 194 PIDMIKVKIQLGEGSAAQV------AKTMYANEGLGSFYKGLSAGLLR 319 P+D ++ ++ + G A + + + A EG+GS +KG A +LR Sbjct: 247 PLDTVRRRMMMTSGQAVKYDGAFDCLRKIVAAEGVGSLFKGCGANILR 294
>ARGO_PHOLL (Q7N183) Arginine exporter protein argO| Length = 207 Score = 31.2 bits (69), Expect = 2.4 Identities = 14/36 (38%), Positives = 20/36 (55%) Frame = -3 Query: 243 AADPSPNWIFTLIMSMGWMTQVASIPEAPPLTNGFI 136 AA S +W F+L + W + V S P + + NGFI Sbjct: 152 AASASVSWFFSLSLLAAWFSPVLSKPLSQRIINGFI 187
>UT14B_MOUSE (Q6EJB6) U3 small nucleolar RNA-associated protein 14 homolog B| (Juvenile spermatogonial depletion protein) Length = 756 Score = 30.8 bits (68), Expect = 3.1 Identities = 17/42 (40%), Positives = 19/42 (45%) Frame = +2 Query: 44 HFLSQPG*ISPEEMADAKQQQAAAPTGVWKTIKPFVNGGASG 169 H L Q G +S EE K G WK +KP N ASG Sbjct: 493 HVLEQQGELSKEEHYPKKGLSRPLLKGDWKEMKPLTNPDASG 534
>ADT_ORYSA (P31691) ADP,ATP carrier protein, mitochondrial precursor (ADP/ATP| translocase) (Adenine nucleotide translocator) (ANT) Length = 382 Score = 30.8 bits (68), Expect = 3.1 Identities = 25/86 (29%), Positives = 38/86 (44%), Gaps = 20/86 (23%) Frame = +2 Query: 122 GVWKTIKPFVNGG----------ASGMLAT----CVIQPIDMIKVKIQLGEGSAAQVAKT 259 G++ ++KP V G A G L T PID ++ ++ + G A + + Sbjct: 269 GMYDSLKPVVLTGSLQDNFFASFALGWLITNGAGLASYPIDTVRRRMMMTSGEAVKYKSS 328 Query: 260 MYA------NEGLGSFYKGLSAGLLR 319 M A NEG S +KG A +LR Sbjct: 329 MDAFSQILKNEGAKSLFKGAGANILR 354
>Y051_MYCTU (Q10880) Hypothetical protein Rv0083/MT0090| Length = 640 Score = 30.8 bits (68), Expect = 3.1 Identities = 32/129 (24%), Positives = 55/129 (42%) Frame = +2 Query: 203 MIKVKIQLGEGSAAQVAKTMYANEGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIE 382 +++ I G VA T G+ + GLS + +A G + ++ + Sbjct: 377 LVQSLIHAAPGHDPIVALTTPLAVGVVALATGLSVAAMTKA------FGIGFLARPRSTQ 430 Query: 383 ANDGRPLPLVQKAFIGLTAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYR 562 A R P +A + + AGA +P +A + +A +TLPAAQ + A+ R Sbjct: 431 AEAAREAPASMRAGMAIAAGACLVLAVAPLLVAPMVRRAAATLPAAQAVKF-TGLGAVVR 489 Query: 563 ITADEGVLA 589 + A G +A Sbjct: 490 LPAMSGSIA 498
>TRX_DROME (P20659) Protein trithorax| Length = 3726 Score = 30.4 bits (67), Expect = 4.1 Identities = 11/26 (42%), Positives = 18/26 (69%) Frame = -2 Query: 394 PIICLNCFVCQNPEGSKTSCRIGSLP 317 P+IC+NC C++ +K S +G+LP Sbjct: 1384 PLICVNCLKCKSCSTTKVSKFVGNLP 1409
>RM19_RECAM (O21264) Mitochondrial 60S ribosomal protein L19| Length = 113 Score = 30.0 bits (66), Expect = 5.3 Identities = 14/47 (29%), Positives = 23/47 (48%) Frame = +2 Query: 215 KIQLGEGSAAQVAKTMYANEGLGSFYKGLSAGLLRQATYTTARLGSF 355 K Q+ G + T Y N+ KG+ G+ ++ YTT +L +F Sbjct: 20 KTQIQSGDILSITTTQYKNKKRKQNLKGICIGIKKRIGYTTIQLRNF 66
>TRX_DROVI (Q24742) Protein trithorax| Length = 3828 Score = 30.0 bits (66), Expect = 5.3 Identities = 11/26 (42%), Positives = 18/26 (69%) Frame = -2 Query: 394 PIICLNCFVCQNPEGSKTSCRIGSLP 317 P+IC+NC C++ +K S +G+LP Sbjct: 1371 PLICVNCLKCKSCATTKVSKFVGNLP 1396
>ANT1_ASHGO (Q75A82) Peroxisomal adenine nucleotide transporter 1| Length = 340 Score = 29.6 bits (65), Expect = 6.9 Identities = 32/131 (24%), Positives = 50/131 (38%), Gaps = 9/131 (6%) Frame = +2 Query: 188 IQPIDMIKVKIQLGEGSAAQVAKTMYANEGLGSFYKGLS----AGLLRQAT----YTTAR 343 I+PI + + A + +Y EG+ Y+GL AG ++ + YT R Sbjct: 58 IKPIALRSPQAAEQYKGALDALQRIYGAEGVAGLYRGLGSSTVAGFIQSFSYFFWYTLVR 117 Query: 344 LGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLALIRMQA-DSTLPAA 520 FR+ + +A P LV +G+ A A +P ++ R Q AA Sbjct: 118 KHYFRLKQARGGDARFSTPEELV----LGIVAAATSQLFVNPINVVATRQQTRGQAAGAA 173 Query: 521 QRRHYKNAFHA 553 R HA Sbjct: 174 DMRTVAREVHA 184
>ADT1_GOSHI (O22342) ADP,ATP carrier protein 1, mitochondrial precursor| (ADP/ATP translocase 1) (Adenine nucleotide translocator 1) (ANT 1) Length = 386 Score = 29.3 bits (64), Expect = 9.1 Identities = 22/84 (26%), Positives = 37/84 (44%), Gaps = 12/84 (14%) Frame = +2 Query: 104 QAAAPTGVWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQ-----LGEGSAAQ------- 247 QA A G F+ GG S ++ PI+ +K+ IQ + G ++ Sbjct: 76 QAPAEKGFSSFAIDFLMGGVSAAVSKTAAAPIERVKLLIQNQDEMIKSGRLSEPYKGIGD 135 Query: 248 VAKTMYANEGLGSFYKGLSAGLLR 319 K +EG GS ++G +A ++R Sbjct: 136 CFKRTIKDEGFGSLWRGNTANVIR 159 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 75,174,464 Number of Sequences: 219361 Number of extensions: 1499979 Number of successful extensions: 4200 Number of sequences better than 10.0: 166 Number of HSP's better than 10.0 without gapping: 3713 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4002 length of database: 80,573,946 effective HSP length: 107 effective length of database: 57,102,319 effective search space used: 5253413348 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
