ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | bart37e12 |
|---|---|
| Clone Library Name | barley_pub |
>S6PD_MALDO (P28475) NADP-dependent D-sorbitol-6-phosphate dehydrogenase (EC| 1.1.1.200) (Aldose-6-phosphate reductase [NADPH]) (NADP-S6PDH) Length = 310 Score = 150 bits (380), Expect = 1e-36 Identities = 66/114 (57%), Positives = 89/114 (78%) Frame = +2 Query: 92 TATALSSGHEMPAVGLGVWRMDSPAVRGLIHSALRAGYRHFDCAADYKNEAEVGDALAEA 271 + LSSG+EMP +GLG+WR++ ++ +I +A++ GYRHFDCAA YK+EA+VG+ALAEA Sbjct: 2 STVTLSSGYEMPVIGLGLWRLEKDELKEVILNAIKIGYRHFDCAAHYKSEADVGEALAEA 61 Query: 272 FQTGLVKREDLFITTKLWNSDHGHVLEACKDSXXXXXXXXXXXXXIHFPVATKH 433 F+TGLVKRE+LFITTK+WNSDHGHV+EACK+S +H+P+ TKH Sbjct: 62 FKTGLVKREELFITTKIWNSDHGHVVEACKNSLEKLQIDYLDLYLVHYPMPTKH 115
>XYL1_ASPNG (Q9P8R5) NAD(P)H-dependent D-xylose reductase (EC 1.1.1.-) (XR)| Length = 319 Score = 99.0 bits (245), Expect = 4e-21 Identities = 48/119 (40%), Positives = 69/119 (57%), Gaps = 2/119 (1%) Frame = +2 Query: 83 MAATATALSSGHEMPAVGLGVWRMDSPAVRGLIHSALRAGYRHFDCAADYKNEAEVGDAL 262 MA+ L+SG++MP VG G+W++++ I+ A++ GYR FD A DY NE E G + Sbjct: 1 MASPTVKLNSGYDMPLVGFGLWKVNNDTCADQIYHAIKEGYRLFDGACDYGNEVEAGQGI 60 Query: 263 AEAFQTGLVKREDLFITTKLWNSDH--GHVLEACKDSXXXXXXXXXXXXXIHFPVATKH 433 A A + GLVKRE+LFI +KLWNS H V C+ +HFP++ K+ Sbjct: 61 ARAIKDGLVKREELFIVSKLWNSFHDGDRVEPICRKQLADWGIDYFDLYIVHFPISLKY 119
>XYL1_CANPA (Q6Y0Z3) NADH-dependent D-xylose reductase (EC 1.1.1.175) (XR)| Length = 324 Score = 97.8 bits (242), Expect = 1e-20 Identities = 50/117 (42%), Positives = 70/117 (59%), Gaps = 2/117 (1%) Frame = +2 Query: 86 AATATALSSGHEMPAVGLGVWRMDSPAVRGLIHSALRAGYRHFDCAADYKNEAEVGDALA 265 A+ A L+SG+E+P VG G W++ + I+ A+++GYR FD A DY NE EVG+ + Sbjct: 6 ASPAVKLNSGYEIPLVGFGCWKLTNDVASDQIYRAIKSGYRLFDGAEDYANEQEVGEGIK 65 Query: 266 EAFQTGLVKREDLFITTKLWNSDHG--HVLEACKDSXXXXXXXXXXXXXIHFPVATK 430 A + G+VKRE+LFIT+KLWNS H +V A + IHFP+A K Sbjct: 66 RAIKEGIVKREELFITSKLWNSFHDKKNVEVALMKTLSDLNLDYVDLFYIHFPIAQK 122
>XYL1_PACTA (P78736) NAD(P)H-dependent D-xylose reductase (EC 1.1.1.-) (XR)| Length = 318 Score = 97.4 bits (241), Expect = 1e-20 Identities = 46/111 (41%), Positives = 73/111 (65%), Gaps = 2/111 (1%) Frame = +2 Query: 104 LSSGHEMPAVGLGVWRMDSPAVRGLIHSALRAGYRHFDCAADYKNEAEVGDALAEAFQTG 283 L++G ++PA+G+G W++++ A ++++A++ GYR FDCA DY NE EVG+ + A + G Sbjct: 8 LNNGRKIPAIGMGCWKLENAA--DMVYAAIKEGYRLFDCACDYGNEKEVGEGINRAIKDG 65 Query: 284 LVKREDLFITTKLWNSDHG--HVLEACKDSXXXXXXXXXXXXXIHFPVATK 430 LVKR+DLFIT+KLWN+ H +V +A S +HFP++ K Sbjct: 66 LVKRKDLFITSKLWNNFHAKENVKKALMKSLSDFNLDYFDLYLMHFPISFK 116
>XYL2_CANTR (P87039) NADPH-dependent D-xylose reductase II,III (EC 1.1.1.-)| (XR) Length = 324 Score = 96.7 bits (239), Expect = 2e-20 Identities = 49/111 (44%), Positives = 68/111 (61%), Gaps = 2/111 (1%) Frame = +2 Query: 104 LSSGHEMPAVGLGVWRMDSPAVRGLIHSALRAGYRHFDCAADYKNEAEVGDALAEAFQTG 283 L+SG+EMP VG G W++++ I++A++ GYR FD A DY NE EVG+ + A + G Sbjct: 12 LNSGYEMPLVGFGCWKVNNETAADQIYNAIKTGYRLFDGAEDYGNEKEVGEGINRAIKEG 71 Query: 284 LVKREDLFITTKLWNSDHG--HVLEACKDSXXXXXXXXXXXXXIHFPVATK 430 LVKRE+LFIT+KLWN+ H +V A + IHFP+A K Sbjct: 72 LVKREELFITSKLWNNFHDPKNVETALNKTLSDLNLDYVDLFLIHFPIAFK 122
>XYL1_CANTE (O74237) NAD(P)H-dependent D-xylose reductase (EC 1.1.1.-) (XR)| Length = 322 Score = 96.3 bits (238), Expect = 3e-20 Identities = 48/111 (43%), Positives = 66/111 (59%), Gaps = 2/111 (1%) Frame = +2 Query: 104 LSSGHEMPAVGLGVWRMDSPAVRGLIHSALRAGYRHFDCAADYKNEAEVGDALAEAFQTG 283 LSSGH MP++G G W++ + ++ A++AGYR FD A DY NE EVGD + A G Sbjct: 10 LSSGHLMPSIGFGCWKLANATAGEQVYQAIKAGYRLFDGAEDYGNEKEVGDGVKRAIDEG 69 Query: 284 LVKREDLFITTKLWNSDHG--HVLEACKDSXXXXXXXXXXXXXIHFPVATK 430 LVKRE++F+T+KLWN+ H +V A + IHFP+A K Sbjct: 70 LVKREEIFLTSKLWNNYHDPKNVETALNKTLADLKVDYVDLFLIHFPIAFK 120
>XYL1_CANTR (O13283) NAD(P)H-dependent D-xylose reductase I,II (EC 1.1.1.-)| (XR) Length = 324 Score = 95.9 bits (237), Expect = 4e-20 Identities = 49/111 (44%), Positives = 67/111 (60%), Gaps = 2/111 (1%) Frame = +2 Query: 104 LSSGHEMPAVGLGVWRMDSPAVRGLIHSALRAGYRHFDCAADYKNEAEVGDALAEAFQTG 283 L+SG+EMP VG G W++ + I++A++ GYR FD A DY NE EVG+ + A + G Sbjct: 12 LNSGYEMPLVGFGCWKVTNATAADQIYNAIKTGYRLFDGAEDYGNEKEVGEGINRAIKEG 71 Query: 284 LVKREDLFITTKLWNSDHG--HVLEACKDSXXXXXXXXXXXXXIHFPVATK 430 LVKRE+LFIT+KLWN+ H +V A + IHFP+A K Sbjct: 72 LVKREELFITSKLWNNFHDPKNVETALNKTLSDLNLDYVDLFLIHFPIAFK 122
>GRE3_YEAST (P38715) NADPH-dependent aldose reductase GRE3 (EC 1.1.1.21)| (NADPH-dependent aldo-keto reductase GRE3) (NADPH-dependent methylglyoxal reductase GRE3) (EC 1.1.1.-) (Xylose reductase) (EC 1.1.1.-) (Genes de respuesta a estres protein 3) Length = 327 Score = 95.5 bits (236), Expect = 5e-20 Identities = 47/117 (40%), Positives = 68/117 (58%), Gaps = 2/117 (1%) Frame = +2 Query: 89 ATATALSSGHEMPAVGLGVWRMDSPAVRGLIHSALRAGYRHFDCAADYKNEAEVGDALAE 268 ++ L++G +MP VGLG W++D I+ A++ GYR FD A DY NE EVG+ + + Sbjct: 2 SSLVTLNNGLKMPLVGLGCWKIDKKVCANQIYEAIKLGYRLFDGACDYGNEKEVGEGIRK 61 Query: 269 AFQTGLVKREDLFITTKLWNSDH--GHVLEACKDSXXXXXXXXXXXXXIHFPVATKH 433 A GLV R+D+F+ +KLWN+ H HV A K + IHFP+A K+ Sbjct: 62 AISEGLVSRKDIFVVSKLWNNFHHPDHVKLALKKTLSDMGLDYLDLYYIHFPIAFKY 118
>XYL1_TRIRE (Q876L8) NAD(P)H-dependent D-xylose reductase (EC 1.1.1.-) (XR)| Length = 324 Score = 95.1 bits (235), Expect = 6e-20 Identities = 47/119 (39%), Positives = 69/119 (57%), Gaps = 2/119 (1%) Frame = +2 Query: 83 MAATATALSSGHEMPAVGLGVWRMDSPAVRGLIHSALRAGYRHFDCAADYKNEAEVGDAL 262 MA+ L+SG++MP VG G+W++D+ +++A++AGYR FD A DY NE E G+ + Sbjct: 1 MASPTLKLNSGYDMPQVGFGLWKVDNAVCADTVYNAIKAGYRLFDGACDYGNEKECGEGV 60 Query: 263 AEAFQTGLVKREDLFITTKLWNS--DHGHVLEACKDSXXXXXXXXXXXXXIHFPVATKH 433 A A + GLVKREDLFI +KLW + D V + +HFP A ++ Sbjct: 61 ARAIKDGLVKREDLFIVSKLWQTFHDEDKVEPITRRQLADWQIDYFDLFLVHFPAALEY 119
>XYL1_PICGU (O94735) NADPH-dependent D-xylose reductase (EC 1.1.1.-) (XR)| Length = 317 Score = 95.1 bits (235), Expect = 6e-20 Identities = 47/111 (42%), Positives = 67/111 (60%), Gaps = 2/111 (1%) Frame = +2 Query: 104 LSSGHEMPAVGLGVWRMDSPAVRGLIHSALRAGYRHFDCAADYKNEAEVGDALAEAFQTG 283 L+SG++MP+VG G W++D+ I++A++ GYR FD A DY NE EVGD + A G Sbjct: 5 LNSGYDMPSVGFGCWKVDNATCADTIYNAIKVGYRLFDGAEDYGNEKEVGDGINRALDEG 64 Query: 284 LVKREDLFITTKLWNSDHG--HVLEACKDSXXXXXXXXXXXXXIHFPVATK 430 LV R++LF+ +KLWNS H +V +A + IHFP+A K Sbjct: 65 LVARDELFVVSKLWNSFHDPKNVEKALDKTLSDLKVDYLDLFLIHFPIAFK 115
>XYL1_CANSH (Q9P430) NAD(P)H-dependent D-xylose reductase (EC 1.1.1.-) (XR)| Length = 323 Score = 92.0 bits (227), Expect = 5e-19 Identities = 45/114 (39%), Positives = 67/114 (58%), Gaps = 2/114 (1%) Frame = +2 Query: 95 ATALSSGHEMPAVGLGVWRMDSPAVRGLIHSALRAGYRHFDCAADYKNEAEVGDALAEAF 274 A L++G EMP++G G W++D +++A++AGYR FD A DY NE EVG+ + A Sbjct: 8 AFKLNNGLEMPSIGFGCWKLDKSTAADQVYNAIKAGYRLFDGAEDYGNEQEVGEGVKRAI 67 Query: 275 QTGLVKREDLFITTKLWNSDHG--HVLEACKDSXXXXXXXXXXXXXIHFPVATK 430 G+V RE++F+T+KLWN+ H +V A + IHFP+A K Sbjct: 68 DEGIVTREEIFLTSKLWNNYHDPKNVETALNKTLKDLKVDYVDLFLIHFPIAFK 121
>XYL1_KLULA (P49378) NAD(P)H-dependent D-xylose reductase (EC 1.1.1.-) (XR)| Length = 329 Score = 92.0 bits (227), Expect = 5e-19 Identities = 49/116 (42%), Positives = 65/116 (56%), Gaps = 2/116 (1%) Frame = +2 Query: 89 ATATALSSGHEMPAVGLGVWRMDSPAVRGLIHSALRAGYRHFDCAADYKNEAEVGDALAE 268 A L++G +MP VGLG W+M + I+ A++ GYR FD A DY NE EVG + Sbjct: 5 AETVTLNNGEKMPLVGLGCWKMPNDVCADQIYEAIKIGYRLFDGAQDYANEKEVGQGVNR 64 Query: 269 AFQTGLVKREDLFITTKLWNSDH--GHVLEACKDSXXXXXXXXXXXXXIHFPVATK 430 A + GLVKREDL + +KLWNS H +V A + + IHFP+A K Sbjct: 65 AIKEGLVKREDLVVVSKLWNSFHHPDNVPRALERTLSDLQLDYVDIFYIHFPLAFK 120
>XYL1_PICST (P31867) NAD(P)H-dependent D-xylose reductase (EC 1.1.1.-) (XR)| Length = 318 Score = 91.7 bits (226), Expect = 7e-19 Identities = 48/111 (43%), Positives = 65/111 (58%), Gaps = 2/111 (1%) Frame = +2 Query: 104 LSSGHEMPAVGLGVWRMDSPAVRGLIHSALRAGYRHFDCAADYKNEAEVGDALAEAFQTG 283 L+SG++MPAVG G W++D I+ A++ GYR FD A DY NE VG + +A G Sbjct: 6 LNSGYDMPAVGFGCWKVDVDTCSEQIYRAIKTGYRLFDGAEDYANEKLVGAGVKKAIDEG 65 Query: 284 LVKREDLFITTKLWNSDH--GHVLEACKDSXXXXXXXXXXXXXIHFPVATK 430 +VKREDLF+T+KLWN+ H +V +A + IHFPV K Sbjct: 66 IVKREDLFLTSKLWNNYHHPDNVEKALNRTLSDLQVDYVDLFLIHFPVTFK 116
>AK1A1_MOUSE (Q9JII6) Alcohol dehydrogenase [NADP+] (EC 1.1.1.2) (Aldehyde| reductase) (Aldo-keto reductase family 1 member A1) Length = 324 Score = 89.7 bits (221), Expect = 3e-18 Identities = 41/84 (48%), Positives = 58/84 (69%), Gaps = 1/84 (1%) Frame = +2 Query: 89 ATATALSSGHEMPAVGLGVWRMDSPAVRGLIHSALRAGYRHFDCAADYKNEAEVGDALAE 268 A++ L +G +MP +GLG W+ + V+ I AL AGYRH DCA+ Y NE E+G+AL E Sbjct: 2 ASSVLLHTGQKMPLIGLGTWKSEPGQVKAAIKHALSAGYRHIDCASVYGNETEIGEALKE 61 Query: 269 AFQTG-LVKREDLFITTKLWNSDH 337 + +G V RE+LF+T+KLWN+ H Sbjct: 62 SVGSGKAVPREELFVTSKLWNTKH 85
>DKGA_ECO57 (Q8XBT6) 2,5-diketo-D-gluconic acid reductase A (EC 1.1.1.274)| (2,5-DKG reductase A) (2,5-DKGR A) (25DKGR-A) (AKR5C) Length = 275 Score = 89.7 bits (221), Expect = 3e-18 Identities = 51/110 (46%), Positives = 58/110 (52%) Frame = +2 Query: 92 TATALSSGHEMPAVGLGVWRMDSPAVRGLIHSALRAGYRHFDCAADYKNEAEVGDALAEA 271 T L G+ MP +GLGVW+ + V I AL GYR FD AA YKNE VG AL A Sbjct: 5 TVIKLQDGNVMPQLGLGVWQASNEEVITAIQKALEVGYRSFDTAAAYKNEEGVGKALKNA 64 Query: 272 FQTGLVKREDLFITTKLWNSDHGHVLEACKDSXXXXXXXXXXXXXIHFPV 421 V RE+LFITTKLWN DH EA DS +H+PV Sbjct: 65 ----SVNREELFITTKLWNDDHNRPREALLDSLKKLQLDYIDLYLMHWPV 110
>AK1A1_PIG (P50578) Alcohol dehydrogenase [NADP+] (EC 1.1.1.2) (Aldehyde| reductase) (Aldo-keto reductase family 1 member A1) Length = 324 Score = 89.0 bits (219), Expect = 5e-18 Identities = 42/85 (49%), Positives = 55/85 (64%), Gaps = 1/85 (1%) Frame = +2 Query: 86 AATATALSSGHEMPAVGLGVWRMDSPAVRGLIHSALRAGYRHFDCAADYKNEAEVGDALA 265 AA+ L +G +MP +GLG W+ + V+ I AL GYRH DCAA Y NE E+G+AL Sbjct: 1 AASCVLLHTGQKMPLIGLGTWKSEPGQVKAAIKYALTVGYRHIDCAAIYGNELEIGEALT 60 Query: 266 EAFQTG-LVKREDLFITTKLWNSDH 337 E G V RE+LF+T+KLWN+ H Sbjct: 61 ETVGPGKAVPREELFVTSKLWNTKH 85
>AK1A1_RAT (P51635) Alcohol dehydrogenase [NADP+] (EC 1.1.1.2) (Aldehyde| reductase) (Aldo-keto reductase family 1 member A1) (3-DG-reducing enzyme) Length = 324 Score = 87.4 bits (215), Expect = 1e-17 Identities = 40/84 (47%), Positives = 56/84 (66%), Gaps = 1/84 (1%) Frame = +2 Query: 89 ATATALSSGHEMPAVGLGVWRMDSPAVRGLIHSALRAGYRHFDCAADYKNEAEVGDALAE 268 A++ L +G +MP +GLG W+ + V+ I AL GYRH DCA+ Y NE E+G+AL E Sbjct: 2 ASSVLLHTGQKMPLIGLGTWKSEPGQVKAAIKYALSVGYRHIDCASVYGNETEIGEALKE 61 Query: 269 AFQTG-LVKREDLFITTKLWNSDH 337 + G V RE+LF+T+KLWN+ H Sbjct: 62 SVGAGKAVPREELFVTSKLWNTKH 85
>AK1A1_HUMAN (P14550) Alcohol dehydrogenase [NADP+] (EC 1.1.1.2) (Aldehyde| reductase) (Aldo-keto reductase family 1 member A1) Length = 324 Score = 87.4 bits (215), Expect = 1e-17 Identities = 41/85 (48%), Positives = 55/85 (64%), Gaps = 1/85 (1%) Frame = +2 Query: 86 AATATALSSGHEMPAVGLGVWRMDSPAVRGLIHSALRAGYRHFDCAADYKNEAEVGDALA 265 AA+ L +G +MP +GLG W+ + V+ + AL GYRH DCAA Y NE E+G+AL Sbjct: 1 AASCVLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALK 60 Query: 266 EAFQTG-LVKREDLFITTKLWNSDH 337 E G V RE+LF+T+KLWN+ H Sbjct: 61 EDVGPGKAVPREELFVTSKLWNTKH 85
>DTDH_MUCMU (Q01213) 4-dihydromethyl-trisporate dehydrogenase (EC 1.1.1.-)| (4-dihydromethyl-TA dehydrogenase) Length = 321 Score = 87.0 bits (214), Expect = 2e-17 Identities = 45/110 (40%), Positives = 59/110 (53%), Gaps = 2/110 (1%) Frame = +2 Query: 110 SGHEMPAVGLGVWRMDSPAVRGLIHSALRAGYRHFDCAADYKNEAEVGDALAEAFQTGLV 289 +G +MP G G W++D+ ++ A++ GYR FD A DY NE EVG + +A GLV Sbjct: 11 TGDKMPIRGFGCWKIDTKDCEETVYQAIKTGYRLFDGACDYGNEVEVGRGINKAINEGLV 70 Query: 290 KREDLFITTKLWNSDHG--HVLEACKDSXXXXXXXXXXXXXIHFPVATKH 433 KREDLFI TKLWN+ H HV IHFPV ++ Sbjct: 71 KREDLFIVTKLWNTFHSKKHVRALFDRQLKDTGLEYFDLYLIHFPVPLQY 120
>DKGA_ECOLI (Q46857) 2,5-diketo-D-gluconic acid reductase A (EC 1.1.1.274)| (2,5-DKG reductase A) (2,5-DKGR A) (25DKGR-A) (AKR5C) Length = 275 Score = 86.7 bits (213), Expect = 2e-17 Identities = 50/110 (45%), Positives = 57/110 (51%) Frame = +2 Query: 92 TATALSSGHEMPAVGLGVWRMDSPAVRGLIHSALRAGYRHFDCAADYKNEAEVGDALAEA 271 T L G+ MP +GLGVW+ + V I AL GYR D AA YKNE VG AL A Sbjct: 5 TVIKLQDGNVMPQLGLGVWQASNEEVITAIQKALEVGYRSIDTAAAYKNEEGVGKALKNA 64 Query: 272 FQTGLVKREDLFITTKLWNSDHGHVLEACKDSXXXXXXXXXXXXXIHFPV 421 V RE+LFITTKLWN DH EA DS +H+PV Sbjct: 65 ----SVNREELFITTKLWNDDHKRPREALLDSLKKLQLDYIDLYLMHWPV 110
>ALDR_RABIT (P15122) Aldose reductase (EC 1.1.1.21) (AR) (Aldehyde reductase)| Length = 315 Score = 86.7 bits (213), Expect = 2e-17 Identities = 47/117 (40%), Positives = 63/117 (53%), Gaps = 2/117 (1%) Frame = +2 Query: 89 ATATALSSGHEMPAVGLGVWRMDSPAVRGLIHSALRAGYRHFDCAADYKNEAEVGDALAE 268 AT L +G +MP +GLG W+ V + +A+ GYRH DCA Y+NE EVG AL E Sbjct: 1 ATHLVLYNGAKMPILGLGTWKSPPGQVTEAVKTAIDLGYRHIDCAHVYQNENEVGVALQE 60 Query: 269 AFQTGLVKREDLFITTKLWNSDHGH--VLEACKDSXXXXXXXXXXXXXIHFPVATKH 433 + +VKRE+LFI +KLW + H V AC+ + IH+P KH Sbjct: 61 KLKEQVVKREELFIVSKLWCTSHDKSLVKGACQKTLNDLKLDYLDLYLIHWPTGFKH 117
>ALDR_PIG (P80276) Aldose reductase (EC 1.1.1.21) (AR) (Aldehyde reductase)| Length = 315 Score = 83.6 bits (205), Expect = 2e-16 Identities = 47/116 (40%), Positives = 61/116 (52%), Gaps = 2/116 (1%) Frame = +2 Query: 89 ATATALSSGHEMPAVGLGVWRMDSPAVRGLIHSALRAGYRHFDCAADYKNEAEVGDALAE 268 A+ L +G +MP +GLG W+ V + A+ GYRH DCA Y+NE EVG L E Sbjct: 1 ASHLVLYTGAKMPILGLGTWKSPPGKVTEAVKVAIDLGYRHIDCAHVYQNENEVGLGLQE 60 Query: 269 AFQTGLVKREDLFITTKLWNSDH--GHVLEACKDSXXXXXXXXXXXXXIHFPVATK 430 Q +VKREDLFI +KLW +DH V AC+ + IH+P K Sbjct: 61 KLQGQVVKREDLFIVSKLWCTDHEKNLVKGACQTTLRDLKLDYLDLYLIHWPTGFK 116
>ALD1_MOUSE (P21300) Aldose reductase-related protein 1 (EC 1.1.1.21) (AR)| (Aldehyde reductase) (VAS deferens androgen-dependent protein) (MVDP) (Aldo-keto reductase family 1 member B7) Length = 315 Score = 83.6 bits (205), Expect = 2e-16 Identities = 40/79 (50%), Positives = 51/79 (64%) Frame = +2 Query: 89 ATATALSSGHEMPAVGLGVWRMDSPAVRGLIHSALRAGYRHFDCAADYKNEAEVGDALAE 268 AT LS+ +MP VGLG W+ V+ + +A+ AGYRH DCA Y NE EVG+A+ E Sbjct: 1 ATFVELSTKAKMPLVGLGTWKSSPGQVKEAVKAAIDAGYRHIDCAYVYHNENEVGEAIQE 60 Query: 269 AFQTGLVKREDLFITTKLW 325 + VKREDLFI +KLW Sbjct: 61 KIKENAVKREDLFIVSKLW 79
>AK1BA_HUMAN (O60218) Aldo-keto reductase family 1 member B10 (EC 1.1.1.-)| (Aldose reductase-like) (ARL-1) (Small intestine reductase) (SI reductase) (Aldose reductase-related protein) (ARP) (hARP) Length = 316 Score = 83.2 bits (204), Expect = 3e-16 Identities = 41/79 (51%), Positives = 51/79 (64%) Frame = +2 Query: 89 ATATALSSGHEMPAVGLGVWRMDSPAVRGLIHSALRAGYRHFDCAADYKNEAEVGDALAE 268 AT LS+ +MP VGLG W+ V+ + A+ AGYRH DCA Y+NE EVG+A+ E Sbjct: 2 ATFVELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQE 61 Query: 269 AFQTGLVKREDLFITTKLW 325 Q VKREDLFI +KLW Sbjct: 62 KIQEKAVKREDLFIVSKLW 80
>AK1E1_MOUSE (Q9DCT1) Aldo-keto reductase family 1 member E1 (EC 1.1.1.-)| Length = 301 Score = 83.2 bits (204), Expect = 3e-16 Identities = 42/105 (40%), Positives = 58/105 (55%), Gaps = 2/105 (1%) Frame = +2 Query: 122 MPAVGLGVWRMDSPAVRGLIHSALRAGYRHFDCAADYKNEAEVGDALAEAFQTGLVKRED 301 +P VGLG W+ V + A+ GYRHFDCA Y NE+EVG ++E + G+VKRED Sbjct: 4 IPTVGLGTWKASPGEVTDAVKLAINLGYRHFDCAYLYHNESEVGMGISEKIKEGVVKRED 63 Query: 302 LFITTKLWNSDH--GHVLEACKDSXXXXXXXXXXXXXIHFPVATK 430 LF+ +KLW + H V AC ++ IH+P+ K Sbjct: 64 LFVVSKLWCTCHKKSLVKTACTNTLEALNLDYLDLYLIHWPMGFK 108
>DKGA_SALTY (Q8ZM06) 2,5-diketo-D-gluconic acid reductase A (EC 1.1.1.274)| (2,5-DKG reductase A) (2,5-DKGR A) (25DKGR-A) (AKR5C) Length = 275 Score = 83.2 bits (204), Expect = 3e-16 Identities = 47/110 (42%), Positives = 57/110 (51%) Frame = +2 Query: 92 TATALSSGHEMPAVGLGVWRMDSPAVRGLIHSALRAGYRHFDCAADYKNEAEVGDALAEA 271 T L G+ MP +GLGVW+ + V IH AL GYR D A Y+NE VG AL A Sbjct: 5 TIIRLQDGNVMPQLGLGVWKASNEEVIAAIHKALEVGYRSIDTATAYQNEEGVGKALKAA 64 Query: 272 FQTGLVKREDLFITTKLWNSDHGHVLEACKDSXXXXXXXXXXXXXIHFPV 421 V RE+LFITTKLWN D EA ++S +H+PV Sbjct: 65 ----SVAREELFITTKLWNDDQKRPREALQESLKKLQLDYLDLYLMHWPV 110
>DKGA_SALTI (P58744) 2,5-diketo-D-gluconic acid reductase A (EC 1.1.1.274)| (2,5-DKG reductase A) (2,5-DKGR A) (25DKGR-A) (AKR5C) Length = 275 Score = 83.2 bits (204), Expect = 3e-16 Identities = 47/110 (42%), Positives = 57/110 (51%) Frame = +2 Query: 92 TATALSSGHEMPAVGLGVWRMDSPAVRGLIHSALRAGYRHFDCAADYKNEAEVGDALAEA 271 T L G+ MP +GLGVW+ + V IH AL GYR D A Y+NE VG AL A Sbjct: 5 TIIRLQDGNVMPQLGLGVWKASNEEVIAAIHKALEVGYRSIDTATAYQNEEGVGKALKAA 64 Query: 272 FQTGLVKREDLFITTKLWNSDHGHVLEACKDSXXXXXXXXXXXXXIHFPV 421 V RE+LFITTKLWN D EA ++S +H+PV Sbjct: 65 ----SVAREELFITTKLWNDDQKRPREALQESLKKLQLDYLDLYLMHWPV 110
>ALDR_RAT (P07943) Aldose reductase (EC 1.1.1.21) (AR) (Aldehyde reductase)| Length = 315 Score = 82.8 bits (203), Expect = 3e-16 Identities = 45/116 (38%), Positives = 62/116 (53%), Gaps = 2/116 (1%) Frame = +2 Query: 89 ATATALSSGHEMPAVGLGVWRMDSPAVRGLIHSALRAGYRHFDCAADYKNEAEVGDALAE 268 A+ L++G +MP +GLG W+ V + A+ GYRH DCA Y+NE EVG AL E Sbjct: 1 ASHLELNNGTKMPTLGLGTWKSPPGQVTEAVKVAIDMGYRHIDCAQVYQNEKEVGVALQE 60 Query: 269 AFQTGLVKREDLFITTKLWNS--DHGHVLEACKDSXXXXXXXXXXXXXIHFPVATK 430 + +VKR+DLFI +KLW + D V AC+ + IH+P K Sbjct: 61 KLKEQVVKRQDLFIVSKLWCTFHDQSMVKGACQKTLSDLQLDYLDLYLIHWPTGFK 116
>ALDR_HUMAN (P15121) Aldose reductase (EC 1.1.1.21) (AR) (Aldehyde reductase)| Length = 315 Score = 82.8 bits (203), Expect = 3e-16 Identities = 45/116 (38%), Positives = 63/116 (54%), Gaps = 2/116 (1%) Frame = +2 Query: 89 ATATALSSGHEMPAVGLGVWRMDSPAVRGLIHSALRAGYRHFDCAADYKNEAEVGDALAE 268 A+ L++G +MP +GLG W+ V + A+ GYRH DCA Y+NE EVG A+ E Sbjct: 1 ASRLLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQE 60 Query: 269 AFQTGLVKREDLFITTKLWNSDH--GHVLEACKDSXXXXXXXXXXXXXIHFPVATK 430 + +VKRE+LFI +KLW + H G V AC+ + IH+P K Sbjct: 61 KLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFK 116
>ALD2_MOUSE (P45377) Aldose reductase-related protein 2 (EC 1.1.1.21) (AR)| (Aldehyde reductase) (Fibroblast growth factor-regulated protein) (FR-1 protein) Length = 315 Score = 80.5 bits (197), Expect = 2e-15 Identities = 39/79 (49%), Positives = 51/79 (64%) Frame = +2 Query: 89 ATATALSSGHEMPAVGLGVWRMDSPAVRGLIHSALRAGYRHFDCAADYKNEAEVGDALAE 268 AT LS+ +MP VGLG W+ V+ + +A+ AGYRH DCA Y NE EVG+A+ E Sbjct: 1 ATFVELSTKAKMPIVGLGTWKSPPNQVKEAVKAAIDAGYRHIDCAYAYCNENEVGEAIQE 60 Query: 269 AFQTGLVKREDLFITTKLW 325 + V+REDLFI +KLW Sbjct: 61 KIKEKAVQREDLFIVSKLW 79
>ALDR_BOVIN (P16116) Aldose reductase (EC 1.1.1.21) (AR) (Aldehyde reductase)| (20-alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.149) (20-alpha-HSD) Length = 315 Score = 79.7 bits (195), Expect = 3e-15 Identities = 45/111 (40%), Positives = 58/111 (52%), Gaps = 2/111 (1%) Frame = +2 Query: 104 LSSGHEMPAVGLGVWRMDSPAVRGLIHSALRAGYRHFDCAADYKNEAEVGDALAEAFQTG 283 L +G +MP +GLG W+ V + A+ GYRH DCA Y+NE EVG AL Q Sbjct: 6 LYTGAKMPILGLGTWKSPPGKVTEAVKVAIDLGYRHIDCAHVYQNENEVGLALQAKLQEQ 65 Query: 284 LVKREDLFITTKLWNSDHGH--VLEACKDSXXXXXXXXXXXXXIHFPVATK 430 +VKREDLFI +KLW + H V AC+ + IH+P K Sbjct: 66 VVKREDLFIVSKLWCTYHDKDLVKGACQKTLSDLKLDYLDLYLIHWPTGFK 116
>ALDR_MOUSE (P45376) Aldose reductase (EC 1.1.1.21) (AR) (Aldehyde reductase)| Length = 315 Score = 78.6 bits (192), Expect = 6e-15 Identities = 38/83 (45%), Positives = 52/83 (62%) Frame = +2 Query: 89 ATATALSSGHEMPAVGLGVWRMDSPAVRGLIHSALRAGYRHFDCAADYKNEAEVGDALAE 268 A+ L++G +MP +GLG W+ V + A+ GYRH DCA Y+NE EVG AL E Sbjct: 1 ASHLELNNGTKMPTLGLGTWKSPPGQVTEAVKVAIDLGYRHIDCAQVYQNEKEVGVALQE 60 Query: 269 AFQTGLVKREDLFITTKLWNSDH 337 + +VKR+DLFI +KLW + H Sbjct: 61 KLKEQVVKRQDLFIVSKLWCTFH 83
>ALD2_CRIGR (O08782) Aldose reductase-related protein 2 (EC 1.1.1.21) (AR)| (Aldehyde reductase) (Aldo-keto reductase) Length = 315 Score = 78.6 bits (192), Expect = 6e-15 Identities = 38/79 (48%), Positives = 50/79 (63%) Frame = +2 Query: 89 ATATALSSGHEMPAVGLGVWRMDSPAVRGLIHSALRAGYRHFDCAADYKNEAEVGDALAE 268 +T LS+ +MP VGLG W+ V+ + A+ AGYRH DCA Y NE EVG+A+ E Sbjct: 1 STFVELSTKAKMPIVGLGTWQSPPGQVKEAVKVAIDAGYRHIDCAYAYYNEHEVGEAIQE 60 Query: 269 AFQTGLVKREDLFITTKLW 325 + V+REDLFI +KLW Sbjct: 61 KIKEKAVRREDLFIVSKLW 79
>P100_LEIMA (P22045) Probable reductase (EC 1.1.-.-)| Length = 284 Score = 77.8 bits (190), Expect = 1e-14 Identities = 48/116 (41%), Positives = 63/116 (54%), Gaps = 3/116 (2%) Frame = +2 Query: 80 GMAATATALSSGHEMPAVGLGVWRMDSPAV-RGLIHSALRAGYRHFDCAADYKNEAEVGD 256 G+ LS+G +MP GLGVW+ + V ++ AL AGYRH D AA YKNE VG Sbjct: 3 GVDKAMVTLSNGVKMPQFGLGVWQSPAGEVTENAVNWALCAGYRHIDTAAIYKNEESVGA 62 Query: 257 ALAEAFQTGLVKREDLFITTKLWNSDHGH--VLEACKDSXXXXXXXXXXXXXIHFP 418 L + V RED+FITTKLWN++ G+ L A ++S IH+P Sbjct: 63 GL----RASGVPREDVFITTKLWNTEQGYESTLAAFEESRQKLGVDYIDLYLIHWP 114
>ALDR_HORVU (P23901) Aldose reductase (EC 1.1.1.21) (AR) (Aldehyde reductase)| Length = 320 Score = 76.6 bits (187), Expect = 2e-14 Identities = 44/111 (39%), Positives = 57/111 (51%), Gaps = 2/111 (1%) Frame = +2 Query: 104 LSSGHEMPAVGLGVWRMDSPAVRGLIHSALRAGYRHFDCAADYKNEAEVGDALAEAFQTG 283 L SGH MPAVGLG WR S + + AGYRH D AA+Y E EVG L A + G Sbjct: 18 LKSGHAMPAVGLGTWRAGSDTAHSVRTAITEAGYRHVDTAAEYGVEKEVGKGLKAAMEAG 77 Query: 284 LVKREDLFITTKLW--NSDHGHVLEACKDSXXXXXXXXXXXXXIHFPVATK 430 + R+DLF+T+K+W N V A +++ IH+P K Sbjct: 78 -IDRKDLFVTSKIWCTNLAPERVRPALENTLKDLQLDYIDLYHIHWPFRLK 127
>AK1A1_CRIGR (O70473) Alcohol dehydrogenase [NADP+] (EC 1.1.1.2) (Aldehyde| reductase) (Aldo-keto reductase family 1 member A1) (Fragment) Length = 228 Score = 75.9 bits (185), Expect = 4e-14 Identities = 36/70 (51%), Positives = 46/70 (65%), Gaps = 1/70 (1%) Frame = +2 Query: 131 VGLGVWRMDSPAVRGLIHSALRAGYRHFDCAADYKNEAEVGDALAEAFQTG-LVKREDLF 307 +GLG W+ + V+ I AL GYRH DCAA Y NE E+G+AL E G V RE+LF Sbjct: 2 IGLGTWKSNPGQVKAAIKYALSVGYRHIDCAAVYGNEIEIGEALKENVGPGKAVPREELF 61 Query: 308 ITTKLWNSDH 337 +T+KLWN+ H Sbjct: 62 VTSKLWNTKH 71
>AKC1H_RAT (P51652) Aldo-keto reductase family 1 member C18 (EC 1.1.-.-)| (20-alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.149) (20-alpha-HSD) (HSD1) Length = 323 Score = 75.1 bits (183), Expect = 7e-14 Identities = 39/114 (34%), Positives = 61/114 (53%), Gaps = 5/114 (4%) Frame = +2 Query: 104 LSSGHEMPAVGLGVWRMDSPAVRGLIHS---ALRAGYRHFDCAADYKNEAEVGDALAEAF 274 L+ GH +P +G G + + + + S A+ G+RH DC+ Y+NE E+G A+ Sbjct: 10 LNDGHSIPVLGFGTYATEENLRKKSMESTKIAIDVGFRHIDCSHLYQNEEEIGQAIVSKI 69 Query: 275 QTGLVKREDLFITTKLWNSDHGH--VLEACKDSXXXXXXXXXXXXXIHFPVATK 430 + G VKRED+F T+KLW++ H V + ++S IHFPV+ K Sbjct: 70 EDGTVKREDIFYTSKLWSTSHRPELVRPSLENSLRKLNLDYVDLYLIHFPVSLK 123
>ALDX_SPOSA (P27800) Aldehyde reductase 1 (EC 1.1.1.2) (Aldehyde reductase I)| (Alcohol dehydrogenase [NADP+]) (ALR) Length = 322 Score = 73.9 bits (180), Expect = 2e-13 Identities = 45/111 (40%), Positives = 57/111 (51%), Gaps = 2/111 (1%) Frame = +2 Query: 98 TALSSGHEMPAVGLGVWRMDSPAVRGLIHSALRAGYRHFDCAADYKNEAEVGDALAEAFQ 277 T L++G + VG G W+ V + A+ GYRH D A Y N+ EVG A+ EA Sbjct: 4 TTLNTGASLELVGYGTWQAAPGEVGQGVKVAIETGYRHLDLAKVYSNQPEVGAAIKEAG- 62 Query: 278 TGLVKREDLFITTKLWNSDH--GHVLEACKDSXXXXXXXXXXXXXIHFPVA 424 VKREDLFIT+KLWN+ H V A D+ IH+PVA Sbjct: 63 ---VKREDLFITSKLWNNSHRPEQVEPALDDTLKELGLEYLDLYLIHWPVA 110
>YDG7_SCHPO (Q10494) Probable oxidoreductase C26F1.07 in chromosome I (EC| 1.-.-.-) Length = 321 Score = 73.2 bits (178), Expect = 3e-13 Identities = 40/111 (36%), Positives = 62/111 (55%), Gaps = 2/111 (1%) Frame = +2 Query: 104 LSSGHEMPAVGLGVWRMDSPAVRGLIHSALRAGYRHFDCAADYKNEAEVGDALAEAFQTG 283 L+ G ++P +GLG WR + + + +AL+ GYRH D AA Y NE EVGD + E+ Sbjct: 18 LADGSKIPGLGLGTWRSEPNQTKNAVKTALQYGYRHIDAAAIYGNEDEVGDGIKESG--- 74 Query: 284 LVKREDLFITTKLWNSDHG--HVLEACKDSXXXXXXXXXXXXXIHFPVATK 430 V R+D+++T+KLW + H V +A + + IH+PV+ K Sbjct: 75 -VPRKDIWVTSKLWCNAHAPEAVPKALEKTLKDLKLDYLDEYLIHWPVSFK 124
>DKGA_YERPE (Q8ZI40) 2,5-diketo-D-gluconic acid reductase A (EC 1.1.1.274)| (2,5-DKG reductase A) (2,5-DKGR A) (25DKGR-A) (AKR5C) Length = 277 Score = 73.2 bits (178), Expect = 3e-13 Identities = 43/105 (40%), Positives = 52/105 (49%) Frame = +2 Query: 104 LSSGHEMPAVGLGVWRMDSPAVRGLIHSALRAGYRHFDCAADYKNEAEVGDALAEAFQTG 283 L G MP +GLGVW+ + AL GYR D AA YKNE VG AL A Sbjct: 9 LYDGRLMPQLGLGVWQASIQETELAVSKALEVGYRSIDTAAIYKNEEGVGKALKAA---- 64 Query: 284 LVKREDLFITTKLWNSDHGHVLEACKDSXXXXXXXXXXXXXIHFP 418 V R++LFITTKLWN D + +A + S IH+P Sbjct: 65 AVARDELFITTKLWNDDQHNPQQALETSLQKLQLDYVDLYLIHWP 109
>AKC1H_MOUSE (Q8K023) Aldo-keto reductase family 1 member C18 (EC 1.1.-.-)| (20-alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.149) (20-alpha-HSD) Length = 323 Score = 72.0 bits (175), Expect = 6e-13 Identities = 38/114 (33%), Positives = 60/114 (52%), Gaps = 5/114 (4%) Frame = +2 Query: 104 LSSGHEMPAVGLGVWRMDSPAVRGLIHS---ALRAGYRHFDCAADYKNEAEVGDALAEAF 274 L+ GH +P +G G + + + + S A+ G+ H DC+ Y+NE E+G A+ Sbjct: 10 LNDGHSIPVLGFGTYATEEHLKKKSMESTKIAIDVGFCHIDCSHLYQNEEEIGQAILSKI 69 Query: 275 QTGLVKREDLFITTKLWNSDHGH--VLEACKDSXXXXXXXXXXXXXIHFPVATK 430 + G VKRED+F T+KLW++ H V + ++S IHFPV+ K Sbjct: 70 EDGTVKREDIFYTSKLWSTSHRPELVRPSLENSLRKLNLDYVDLYLIHFPVSLK 123
>6DCS_SOYBN (P26690) NAD(P)H dependent 6'-deoxychalcone synthase (EC 2.3.1.170)| Length = 315 Score = 72.0 bits (175), Expect = 6e-13 Identities = 44/115 (38%), Positives = 64/115 (55%), Gaps = 7/115 (6%) Frame = +2 Query: 107 SSGHEMPAVGLG-----VWRMDSPAVRGLIHSALRAGYRHFDCAADYKNEAEVGDALAEA 271 S+ MP VG+G + D+ + I A++ GYRHFD AA Y +E +G+AL EA Sbjct: 16 SAQQRMPVVGMGSAPDFTCKKDT---KEAIIEAVKQGYRHFDTAAAYGSEQALGEALKEA 72 Query: 272 FQTGLVKREDLFITTKLW-NSDHGH-VLEACKDSXXXXXXXXXXXXXIHFPVATK 430 GLV R+DLF+T+KLW +H H VL A + S IH+P++++ Sbjct: 73 IHLGLVSRQDLFVTSKLWVTENHPHLVLPALRKSLKTLQLEYLDLYLIHWPLSSQ 127
>PE2R_RABIT (P80508) Prostaglandin-E(2) 9-reductase (EC 1.1.1.189)| (20-alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.149) (20-alpha-HSD) Length = 323 Score = 71.6 bits (174), Expect = 8e-13 Identities = 44/115 (38%), Positives = 58/115 (50%), Gaps = 5/115 (4%) Frame = +2 Query: 101 ALSSGHEMPAVGLGVWRMDSPAVRGLIHS---ALRAGYRHFDCAADYKNEAEVGDALAEA 271 ALS GH +P +G G + + + + A+ AG+RH D A YKNE EVG A+ Sbjct: 9 ALSDGHFIPVLGFGTYAPEEVPKSKAMEATKIAIDAGFRHIDSAYFYKNEKEVGLAIRSK 68 Query: 272 FQTGLVKREDLFITTKLWNSDHGH--VLEACKDSXXXXXXXXXXXXXIHFPVATK 430 G VKRED+F T+KLW + H V + +DS IHFP A K Sbjct: 69 IADGTVKREDIFYTSKLWCTFHRPELVRPSLEDSLKNLQLDYVDLYIIHFPTALK 123
>YPR1_YEAST (Q12458) Putative reductase 1 (EC 1.1.1.-)| Length = 312 Score = 71.6 bits (174), Expect = 8e-13 Identities = 46/124 (37%), Positives = 66/124 (53%), Gaps = 1/124 (0%) Frame = +2 Query: 62 PATDRLGMAATATALSSGHEMPAVGLGVWR-MDSPAVRGLIHSALRAGYRHFDCAADYKN 238 PAT L ++ L++G +P +G G WR +D+ +I +AL+AGYRH D AA Y N Sbjct: 2 PAT--LKNSSATLKLNTGASIPVLGFGTWRSVDNNGYHSVI-AALKAGYRHIDAAAIYLN 58 Query: 239 EAEVGDALAEAFQTGLVKREDLFITTKLWNSDHGHVLEACKDSXXXXXXXXXXXXXIHFP 418 E EVG A+ ++ V RE++FITTKLW ++ A S +H+P Sbjct: 59 EEEVGRAIKDSG----VPREEIFITTKLWGTEQRDPEAALNKSLKRLGLDYVDLYLMHWP 114 Query: 419 VATK 430 V K Sbjct: 115 VPLK 118
>YJ66_YEAST (P47137) Probable oxidoreductase YJR096W (EC 1.-.-.-)| Length = 282 Score = 70.9 bits (172), Expect = 1e-12 Identities = 33/82 (40%), Positives = 51/82 (62%), Gaps = 2/82 (2%) Frame = +2 Query: 104 LSSGHEMPAVGLGVWRMDSPAVRGLIHSALRAGYRHFDCAADYKNEAEVGDALAEAF--Q 277 LS+G ++P++ LG + + +++ ++ GYRHFD A Y NE EVGD + + Sbjct: 8 LSNGFKIPSIALGTYDIPRSQTAEIVYEGVKCGYRHFDTAVLYGNEKEVGDGIIKWLNED 67 Query: 278 TGLVKREDLFITTKLWNSDHGH 343 G KRE++F TTKLWNS +G+ Sbjct: 68 PGNHKREEIFYTTKLWNSQNGY 89
>AK1C2_HUMAN (P52895) Aldo-keto reductase family 1 member C2 (EC 1.-.-.-)| (Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase) (EC 1.3.1.20) (Type III 3-alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.213) (3-alpha-HSD3) (Chlordecone reductase homolog HAKRD) ( Length = 323 Score = 69.3 bits (168), Expect = 4e-12 Identities = 42/114 (36%), Positives = 58/114 (50%), Gaps = 5/114 (4%) Frame = +2 Query: 104 LSSGHEMPAVGLGVWR-MDSPAVRGL--IHSALRAGYRHFDCAADYKNEAEVGDALAEAF 274 L+ GH MP +G G + + P + L + A+ AG+ H D A Y NE +VG A+ Sbjct: 10 LNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRSKI 69 Query: 275 QTGLVKREDLFITTKLWNSDHGH--VLEACKDSXXXXXXXXXXXXXIHFPVATK 430 G VKRED+F T+KLW++ H V A + S IHFPV+ K Sbjct: 70 ADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVK 123
>GCY_YEAST (P14065) GCY protein (EC 1.1.1.-)| Length = 312 Score = 69.3 bits (168), Expect = 4e-12 Identities = 36/106 (33%), Positives = 57/106 (53%) Frame = +2 Query: 101 ALSSGHEMPAVGLGVWRMDSPAVRGLIHSALRAGYRHFDCAADYKNEAEVGDALAEAFQT 280 +L++G ++P +GLG W+ + +AL+ GYRH D AA Y+NE +VG A+ ++ Sbjct: 13 SLNTGAQIPQIGLGTWQSKENDAYKAVLTALKDGYRHIDTAAIYRNEDQVGQAIKDSG-- 70 Query: 281 GLVKREDLFITTKLWNSDHGHVLEACKDSXXXXXXXXXXXXXIHFP 418 V RE++F+TTKLW + H A S +H+P Sbjct: 71 --VPREEIFVTTKLWCTQHHEPEVALDQSLKRLGLDYVDLYLMHWP 114
>AK1D1_MOUSE (Q8VCX1) 3-oxo-5-beta-steroid 4-dehydrogenase (EC 1.3.99.6)| (Delta(4)-3-ketosteroid 5-beta-reductase) (Aldo-keto reductase family 1 member D1) Length = 325 Score = 68.9 bits (167), Expect = 5e-12 Identities = 43/123 (34%), Positives = 60/123 (48%), Gaps = 5/123 (4%) Frame = +2 Query: 77 LGMAATATALSSGHEMPAVGLGVWRMDSPA---VRGLIHSALRAGYRHFDCAADYKNEAE 247 L A +LS G+ +P +GLG + P + +A+ GYRH D A Y NE E Sbjct: 3 LSAAHHQISLSDGNNIPLIGLGTYSDPRPVPGKTYVAVKTAIDEGYRHIDGAYVYHNEHE 62 Query: 248 VGDALAEAFQTGLVKREDLFITTKLWNSDH--GHVLEACKDSXXXXXXXXXXXXXIHFPV 421 VG+A+ E G VKRE++F KLWN++H VL A + + I P+ Sbjct: 63 VGEAIREKIAEGKVKREEIFYCGKLWNTEHVPSMVLPALERTLKALKLDYIDLYIIELPM 122 Query: 422 ATK 430 A K Sbjct: 123 AFK 125
>AK1CD_MOUSE (Q8VC28) Aldo-keto reductase family 1 member C13 (EC 1.1.1.-)| Length = 323 Score = 68.2 bits (165), Expect = 8e-12 Identities = 36/77 (46%), Positives = 49/77 (63%), Gaps = 3/77 (3%) Frame = +2 Query: 104 LSSGHEMPAVGLGVWR-MDSPAVRGLIHS--ALRAGYRHFDCAADYKNEAEVGDALAEAF 274 L+ GH +PA+G G ++ + P + L + AL GYRH D A Y+ E E+G A+ Sbjct: 10 LNDGHLIPALGFGTYKPKEVPKSKSLEAACLALDVGYRHVDTAYAYQVEEEIGQAIQSKI 69 Query: 275 QTGLVKREDLFITTKLW 325 + G+VKREDLFITTKLW Sbjct: 70 KAGVVKREDLFITTKLW 86
>AK1C1_HUMAN (Q04828) Aldo-keto reductase family 1 member C1 (EC 1.1.1.-)| (20-alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.149) (20-alpha-HSD) (Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase) (EC 1.3.1.20) (High-affinity hepatic bile acid-binding protei Length = 323 Score = 67.8 bits (164), Expect = 1e-11 Identities = 43/114 (37%), Positives = 58/114 (50%), Gaps = 5/114 (4%) Frame = +2 Query: 104 LSSGHEMPAVGLGVWR-MDSPAVRGLIHS--ALRAGYRHFDCAADYKNEAEVGDALAEAF 274 L+ GH MP +G G + + P + L + A+ AG+RH D A Y NE +VG A+ Sbjct: 10 LNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKI 69 Query: 275 QTGLVKREDLFITTKLWNSDHGH--VLEACKDSXXXXXXXXXXXXXIHFPVATK 430 G VKRED+F T+KLW + H V A + S IHFPV+ K Sbjct: 70 ADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVK 123
>MORA_PSEPU (Q02198) Morphine 6-dehydrogenase (EC 1.1.1.218) (Naloxone| reductase) Length = 295 Score = 67.4 bits (163), Expect = 1e-11 Identities = 39/107 (36%), Positives = 58/107 (54%), Gaps = 2/107 (1%) Frame = +2 Query: 104 LSSGHEMPAVGLGVWRMDSPAVRGLIHSALRAGYRHFDCAADYKNEAEVGDALAEAFQTG 283 L++G +MPA+GLGV+ + I SA+ +GYR D A Y NEA+VG E + Sbjct: 9 LNNGVKMPALGLGVFAASAEETASAIASAISSGYRLIDTARSYNNEAQVG----EGIRNS 64 Query: 284 LVKREDLFITTKLWNSDHGH--VLEACKDSXXXXXXXXXXXXXIHFP 418 V R ++F+TTKL+N D+G+ L A +S +H+P Sbjct: 65 GVDRAEMFVTTKLFNCDYGYERALRAFDESLGRLGLDYVDLYLLHWP 111
>DKGA_CORSC (P06632) 2,5-diketo-D-gluconic acid reductase A (EC 1.1.1.274)| (2,5-DKG reductase A) (2,5-DKGR A) (25DKGR-A) (AKR5C) Length = 277 Score = 67.4 bits (163), Expect = 1e-11 Identities = 34/78 (43%), Positives = 47/78 (60%) Frame = +2 Query: 104 LSSGHEMPAVGLGVWRMDSPAVRGLIHSALRAGYRHFDCAADYKNEAEVGDALAEAFQTG 283 L+ G+ +P +G GV+++ + + AL GYRH D AA Y NE VG A+A + Sbjct: 7 LNDGNSIPQLGYGVFKVPPADTQRAVEEALEVGYRHIDTAAIYGNEEGVGAAIAASG--- 63 Query: 284 LVKREDLFITTKLWNSDH 337 + R+DLFITTKLWN H Sbjct: 64 -IARDDLFITTKLWNDRH 80
>ARA1_YEAST (P38115) D-arabinose dehydrogenase [NAD(P)+] heavy chain (EC| 1.1.1.117) Length = 344 Score = 67.0 bits (162), Expect = 2e-11 Identities = 33/77 (42%), Positives = 49/77 (63%), Gaps = 2/77 (2%) Frame = +2 Query: 101 ALSSGHEMPAVGLGVWRMDSPAV--RGLIHSALRAGYRHFDCAADYKNEAEVGDALAEAF 274 +L++G +PA+GLG + + +A++AGYRH D A Y+ E VG+A+ E Sbjct: 26 SLNNGVRIPALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKELL 85 Query: 275 QTGLVKREDLFITTKLW 325 + G +KREDLFITTK+W Sbjct: 86 EDGSIKREDLFITTKVW 102
>AK1D1_HUMAN (P51857) 3-oxo-5-beta-steroid 4-dehydrogenase (EC 1.3.1.3)| (Delta(4)-3-ketosteroid 5-beta-reductase) (Aldo-keto reductase family 1 member D1) Length = 326 Score = 67.0 bits (162), Expect = 2e-11 Identities = 35/91 (38%), Positives = 50/91 (54%), Gaps = 4/91 (4%) Frame = +2 Query: 77 LGMAATATALSSGHEMPAVGLGVWRMDSPAVRGL----IHSALRAGYRHFDCAADYKNEA 244 L A+ LS G+ +P +GLG + +G + A+ GYRH D A Y+NE Sbjct: 3 LSAASHRIPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEH 62 Query: 245 EVGDALAEAFQTGLVKREDLFITTKLWNSDH 337 EVG+A+ E G V+RED+F KLW ++H Sbjct: 63 EVGEAIREKIAEGKVRREDIFYCGKLWATNH 93
>AK1D1_RAT (P31210) 3-oxo-5-beta-steroid 4-dehydrogenase (EC 1.3.99.6)| (Delta(4)-3-ketosteroid 5-beta-reductase) (Aldo-keto reductase family 1 member D1) Length = 326 Score = 66.6 bits (161), Expect = 2e-11 Identities = 35/82 (42%), Positives = 50/82 (60%), Gaps = 4/82 (4%) Frame = +2 Query: 104 LSSGHEMPAVGLGVWRMDSPAVRG----LIHSALRAGYRHFDCAADYKNEAEVGDALAEA 271 L+ G+ +P +GLG + P V G + +A+ GYRH D A Y+NE EVG+A+ E Sbjct: 12 LNDGNSIPIIGLGTYSDPRP-VPGKTFIAVKTAIDEGYRHIDGAYVYRNEHEVGEAIREK 70 Query: 272 FQTGLVKREDLFITTKLWNSDH 337 G VKRE++F KLW++DH Sbjct: 71 VAEGKVKREEIFYCGKLWSTDH 92
>AK1C1_MACFU (Q95JH6) Aldo-keto reductase family 1 member C1 homolog (EC| 1.-.-.-) (20-alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.149) (20-alpha-HSD) (Dihydrodiol dehydrogenase 1) (DD-1) (DD1) Length = 323 Score = 66.2 bits (160), Expect = 3e-11 Identities = 42/114 (36%), Positives = 54/114 (47%), Gaps = 5/114 (4%) Frame = +2 Query: 104 LSSGHEMPAVGLGVWRMDSPAVRGLIHS---ALRAGYRHFDCAADYKNEAEVGDALAEAF 274 L+ GH MP +G G + I + A+ AG+RH D A Y NE VG A+ Sbjct: 10 LNDGHFMPVLGFGTYAPAEVPKNKAIEATKLAIEAGFRHIDSAHLYNNEEYVGLAIRSKI 69 Query: 275 QTGLVKREDLFITTKLWNSDH--GHVLEACKDSXXXXXXXXXXXXXIHFPVATK 430 G VKRED+F T+KLW + H V A + S IHFPV+ K Sbjct: 70 ADGTVKREDIFYTSKLWCNSHRPEFVRPALERSLKNLQLDYVDLYLIHFPVSLK 123
>AK1C1_MACFA (Q95JH7) Aldo-keto reductase family 1 member C1 homolog (EC| 1.-.-.-) (20-alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.149) (20-alpha-HSD) (Dihydrodiol dehydrogenase 1) (DD-1) (DD1) Length = 323 Score = 66.2 bits (160), Expect = 3e-11 Identities = 43/114 (37%), Positives = 57/114 (50%), Gaps = 5/114 (4%) Frame = +2 Query: 104 LSSGHEMPAVGLGVWR-MDSPAVRGLIHS--ALRAGYRHFDCAADYKNEAEVGDALAEAF 274 L+ GH MP +G G + + P + L + A+ AG+RH D A Y NE VG A+ Sbjct: 10 LNDGHFMPVLGFGTYAPAEVPKNKALEATKLAIEAGFRHIDSAHLYNNEEYVGLAIRSKI 69 Query: 275 QTGLVKREDLFITTKLWNSDH--GHVLEACKDSXXXXXXXXXXXXXIHFPVATK 430 G VKRED+F T+KLW + H V A + S IHFPV+ K Sbjct: 70 ADGTVKREDIFYTSKLWCNSHRPEFVRPALERSLKNLQLDYVDLYLIHFPVSLK 123
>DHB5_MOUSE (P70694) Estradiol 17 beta-dehydrogenase 5 (EC 1.1.1.-)| (17-beta-HSD 5) Length = 323 Score = 65.9 bits (159), Expect = 4e-11 Identities = 40/114 (35%), Positives = 57/114 (50%), Gaps = 5/114 (4%) Frame = +2 Query: 104 LSSGHEMPAVGLGVW---RMDSPAVRGLIHSALRAGYRHFDCAADYKNEAEVGDALAEAF 274 LS GH +P +G G + + A+ AG+RH D A+ Y+NE EVG A+ Sbjct: 10 LSDGHFIPILGFGTYAPQEVPKSKATEATKIAIDAGFRHIDSASMYQNEKEVGLAIRSKI 69 Query: 275 QTGLVKREDLFITTKLWNSDH-GHVLEAC-KDSXXXXXXXXXXXXXIHFPVATK 430 G VKRED+F T+K+W + H ++ C + S IHFP+A K Sbjct: 70 ADGTVKREDIFYTSKVWCTFHRPELVRVCLEQSLKQLQLDYVDLYLIHFPMAMK 123
>DDBX_BOVIN (P52898) Dihydrodiol dehydrogenase 3 (EC 1.-.-.-) (Prostaglandin F| synthase) Length = 323 Score = 65.9 bits (159), Expect = 4e-11 Identities = 42/114 (36%), Positives = 57/114 (50%), Gaps = 5/114 (4%) Frame = +2 Query: 104 LSSGHEMPAVGLGVWR-MDSPAVRGL--IHSALRAGYRHFDCAADYKNEAEVGDALAEAF 274 L+ GH +P +G G + + P L A+ AG+RH D A Y+NE +VG A+ Sbjct: 10 LNDGHFIPVLGFGTFAPREVPKSEALEVTKFAIEAGFRHIDSAHLYQNEEQVGQAIRSKI 69 Query: 275 QTGLVKREDLFITTKLWNSD--HGHVLEACKDSXXXXXXXXXXXXXIHFPVATK 430 G VKRED+F T+KLW++ V A + S IHFPVA K Sbjct: 70 ADGTVKREDIFYTSKLWSTSLRPELVRPALEKSLNNLQLDYVDLYIIHFPVALK 123
>AK1CD_MESAU (P82809) Aldo-keto reductase family 1 member C13 (EC 1.1.1.-)| (Morphine 6-dehydrogenase) (EC 1.1.1.218) Length = 322 Score = 65.5 bits (158), Expect = 5e-11 Identities = 32/74 (43%), Positives = 48/74 (64%), Gaps = 3/74 (4%) Frame = +2 Query: 113 GHEMPAVGLGVWR-MDSPAVRGL--IHSALRAGYRHFDCAADYKNEAEVGDALAEAFQTG 283 GH +PA+G G ++ ++ P + + + A+ GYRH D A Y+ E E+G A+ + G Sbjct: 13 GHCIPALGFGTYKPIEVPKSKAMEAANLAIGVGYRHIDTAYAYQIEEEIGQAIQSNIKAG 72 Query: 284 LVKREDLFITTKLW 325 +VKRED+FITTKLW Sbjct: 73 IVKREDMFITTKLW 86
>AK1C4_MACFA (Q95JH5) Aldo-keto reductase family 1 member C4 (EC 1.1.1.-)| (Chlordecone reductase) (EC 1.1.1.225) (CDR) (3-alpha-hydroxysteroid dehydrogenase type I) (EC 1.1.1.50) (3-alpha-HSD1) (Dihydrodiol dehydrogenase 4) (DD4) (DD-4) Length = 323 Score = 64.7 bits (156), Expect = 9e-11 Identities = 42/115 (36%), Positives = 56/115 (48%), Gaps = 5/115 (4%) Frame = +2 Query: 101 ALSSGHEMPAVGLGVW---RMDSPAVRGLIHSALRAGYRHFDCAADYKNEAEVGDALAEA 271 AL+ GH MP +G G + + V + A+ AG+RH D A Y NE +VG A+ Sbjct: 9 ALNDGHFMPVLGFGTYAPPEVPRNRVVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSK 68 Query: 272 FQTGLVKREDLFITTKLWNSDHGH--VLEACKDSXXXXXXXXXXXXXIHFPVATK 430 G VKRED+F T+KLW + V A + S IHFP+A K Sbjct: 69 IADGSVKREDIFYTSKLWCTFFRPQLVQPALESSLKKLQLDYVDLYLIHFPMALK 123
>AK1C3_PONPY (Q5R7C9) Aldo-keto reductase family 1 member C3 homolog (EC| 1.-.-.-) (Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase) (EC 1.3.1.20) (3-alpha-hydroxysteroid dehydrogenase type 2) (EC 1.1.1.213) (3-alpha-HSD type 2) (Prostaglandin F synthase) Length = 323 Score = 64.7 bits (156), Expect = 9e-11 Identities = 41/114 (35%), Positives = 58/114 (50%), Gaps = 5/114 (4%) Frame = +2 Query: 104 LSSGHEMPAVGLGVWRM-DSPAVRGL--IHSALRAGYRHFDCAADYKNEAEVGDALAEAF 274 L+ GH MP +G G + + P + L A+ AG+RH D A Y NE +VG A+ Sbjct: 10 LNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKI 69 Query: 275 QTGLVKREDLFITTKLWNSDHGH--VLEACKDSXXXXXXXXXXXXXIHFPVATK 430 G VKRED+F T+KLW++ H V A ++S IH P++ K Sbjct: 70 ADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLK 123
>AK1C3_HUMAN (P42330) Aldo-keto reductase family 1 member C3 (EC 1.-.-.-)| (Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase) (EC 1.3.1.20) (3-alpha-hydroxysteroid dehydrogenase type 2) (EC 1.1.1.213) (3-alpha-HSD type 2) (3-alpha-HSD type II, brain) (Prost Length = 323 Score = 64.7 bits (156), Expect = 9e-11 Identities = 41/114 (35%), Positives = 58/114 (50%), Gaps = 5/114 (4%) Frame = +2 Query: 104 LSSGHEMPAVGLGVWRM-DSPAVRGL--IHSALRAGYRHFDCAADYKNEAEVGDALAEAF 274 L+ GH MP +G G + + P + L A+ AG+RH D A Y NE +VG A+ Sbjct: 10 LNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKI 69 Query: 275 QTGLVKREDLFITTKLWNSDHGH--VLEACKDSXXXXXXXXXXXXXIHFPVATK 430 G VKRED+F T+KLW++ H V A ++S IH P++ K Sbjct: 70 ADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLK 123
>AK1C1_PONPY (Q5REQ0) Aldo-keto reductase family 1 member C1 homolog (EC| 1.-.-.-) (20-alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.149) (20-alpha-HSD) Length = 323 Score = 64.7 bits (156), Expect = 9e-11 Identities = 41/114 (35%), Positives = 57/114 (50%), Gaps = 5/114 (4%) Frame = +2 Query: 104 LSSGHEMPAVGLGVWRM-DSPAVRGLIHS--ALRAGYRHFDCAADYKNEAEVGDALAEAF 274 L+ H MP +G G + + P + L + A+ AG+RH D A Y NE +VG A+ Sbjct: 10 LNDSHFMPVLGFGTYAPPEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKI 69 Query: 275 QTGLVKREDLFITTKLWNSDHGH--VLEACKDSXXXXXXXXXXXXXIHFPVATK 430 G VKRED+F T+KLW + H V A + S +HFPV+ K Sbjct: 70 ADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLVHFPVSVK 123
>AK1C4_MACFU (Q95JH4) Aldo-keto reductase family 1 member C4 (EC 1.1.1.-)| (Chlordecone reductase) (EC 1.1.1.225) (CDR) (3-alpha-hydroxysteroid dehydrogenase type I) (EC 1.1.1.50) (3-alpha-HSD1) (Dihydrodiol dehydrogenase 4) (DD4) (DD-4) Length = 323 Score = 63.9 bits (154), Expect = 2e-10 Identities = 42/115 (36%), Positives = 56/115 (48%), Gaps = 5/115 (4%) Frame = +2 Query: 101 ALSSGHEMPAVGLGVW---RMDSPAVRGLIHSALRAGYRHFDCAADYKNEAEVGDALAEA 271 AL+ GH MP +G G + + V + A+ AG+RH D A Y NE +VG A+ Sbjct: 9 ALNDGHFMPVLGFGSYAPPEVPRNRVVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSK 68 Query: 272 FQTGLVKREDLFITTKLWNSDHGH--VLEACKDSXXXXXXXXXXXXXIHFPVATK 430 G VKRED+F T+KLW + V A + S IHFP+A K Sbjct: 69 IADGSVKREDIFYTSKLWCTFFRPQLVQPALESSLKKLQLDYVDLYLIHFPMALK 123
>NADO1_ORYSA (Q7G764) Probable NAD(P)H-dependent oxidoreductase 1 (EC 1.1.1.-)| Length = 321 Score = 63.9 bits (154), Expect = 2e-10 Identities = 39/107 (36%), Positives = 57/107 (53%), Gaps = 6/107 (5%) Frame = +2 Query: 122 MPAVGLGVWRMDSPAVRGLIHSALRA---GYRHFDCAADYKNEAEVGDALAEAFQTGLV- 289 MP VG+G + + LRA GYRHFD A Y E VG+A+AEA + GL+ Sbjct: 16 MPRVGMGTAAFPFTSSEDTTAAMLRAIELGYRHFDTARIYATEGCVGEAVAEAVRRGLIA 75 Query: 290 KREDLFITTKLWNSD--HGHVLEACKDSXXXXXXXXXXXXXIHFPVA 424 R D+F+T+K+W SD G V+ A +++ +H+PV+ Sbjct: 76 SRADVFVTSKIWCSDLHAGRVVPAARETLRNLGMDYVDLLLVHWPVS 122
>DIDH_RAT (P23457) 3-alpha-hydroxysteroid dehydrogenase (EC 1.1.1.213)| (3-alpha-HSD) (Hydroxyprostaglandin dehydrogenase) Length = 322 Score = 63.5 bits (153), Expect = 2e-10 Identities = 39/113 (34%), Positives = 60/113 (53%), Gaps = 5/113 (4%) Frame = +2 Query: 101 ALSSGHEMPAVGLGVWRMDSPAVRGLIHS---ALRAGYRHFDCAADYKNEAEVGDALAEA 271 AL+ G+ +P +G G + A +I + A+ G+RHFD A Y+ E EVG A+ Sbjct: 9 ALNDGNFIPVLGFGTTVPEKVAKDEVIKATKIAIDNGFRHFDSAYLYEVEEEVGQAIRSK 68 Query: 272 FQTGLVKREDLFITTKLWNSDH-GHVLEAC-KDSXXXXXXXXXXXXXIHFPVA 424 + G VKRED+F T+KLW++ H ++ C + + IHFP+A Sbjct: 69 IEDGTVKREDIFYTSKLWSTFHRPELVRTCLEKTLKSTQLDYVDLYIIHFPMA 121
>AK1C4_HUMAN (P17516) Aldo-keto reductase family 1 member C4 (EC 1.1.1.-)| (Chlordecone reductase) (EC 1.1.1.225) (CDR) (3-alpha-hydroxysteroid dehydrogenase type I) (EC 1.1.1.50) (3-alpha-HSD1) (Dihydrodiol dehydrogenase 4) (DD4) (HAKRA) Length = 323 Score = 62.8 bits (151), Expect = 4e-10 Identities = 41/114 (35%), Positives = 56/114 (49%), Gaps = 5/114 (4%) Frame = +2 Query: 104 LSSGHEMPAVGLGVWRM-DSPAVRGL--IHSALRAGYRHFDCAADYKNEAEVGDALAEAF 274 L+ GH MP +G G + + P R + A+ AG+RH D A Y NE +VG A+ Sbjct: 10 LNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSKI 69 Query: 275 QTGLVKREDLFITTKLWNS--DHGHVLEACKDSXXXXXXXXXXXXXIHFPVATK 430 G VKRED+F T+KLW + V A + S +HFP+A K Sbjct: 70 ADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALK 123
>AK1D1_RABIT (Q9TV64) 3-oxo-5-beta-steroid 4-dehydrogenase (EC 1.3.99.6)| (Delta(4)-3-ketosteroid 5-beta-reductase) (Aldo-keto reductase family 1 member D1) Length = 326 Score = 62.8 bits (151), Expect = 4e-10 Identities = 32/86 (37%), Positives = 46/86 (53%), Gaps = 4/86 (4%) Frame = +2 Query: 104 LSSGHEMPAVGLGVWRMDSPAVRGL----IHSALRAGYRHFDCAADYKNEAEVGDALAEA 271 L G+ +P +GLG + +G + A+ GYRH D A Y+NE EVG+ E Sbjct: 12 LGDGNSIPIIGLGTYSEPKTTPKGSCATSVKIAIDTGYRHIDGAYIYQNEHEVGETFREK 71 Query: 272 FQTGLVKREDLFITTKLWNSDHGHVL 349 G V+RED+F KLW ++H V+ Sbjct: 72 IAEGKVRREDIFYCGKLWATNHDPVM 97
>DKGB_SALTY (Q8ZRM7) 2,5-diketo-D-gluconic acid reductase B (EC 1.1.1.274)| (2,5-DKG reductase B) (2,5-DKGR B) (25DKGR-B) (AKR5D) Length = 267 Score = 62.0 bits (149), Expect = 6e-10 Identities = 37/101 (36%), Positives = 52/101 (51%), Gaps = 2/101 (1%) Frame = +2 Query: 122 MPAVGLGVWRMDSPAVRGLIHSALRAGYRHFDCAADYKNEAEVGDALAEAFQTGLVKRED 301 +PA GLG +R+ V + +AL GYR D A Y NEA VG A+AE+ V R + Sbjct: 3 IPAFGLGTFRLKDDVVIASVKTALELGYRAVDTAQIYDNEAAVGQAIAESG----VPRNE 58 Query: 302 LFITTKLW--NSDHGHVLEACKDSXXXXXXXXXXXXXIHFP 418 L+ITTK+W N ++ + K+S IH+P Sbjct: 59 LYITTKIWIENLSKDKLIPSLKESLKKLRTDYVDLTLIHWP 99
>DKGB_SALTI (Q8Z988) 2,5-diketo-D-gluconic acid reductase B (EC 1.1.1.274)| (2,5-DKG reductase B) (2,5-DKGR B) (25DKGR-B) (AKR5D) Length = 267 Score = 62.0 bits (149), Expect = 6e-10 Identities = 37/101 (36%), Positives = 52/101 (51%), Gaps = 2/101 (1%) Frame = +2 Query: 122 MPAVGLGVWRMDSPAVRGLIHSALRAGYRHFDCAADYKNEAEVGDALAEAFQTGLVKRED 301 +PA GLG +R+ V + +AL GYR D A Y NEA VG A+AE+ V R + Sbjct: 3 IPAFGLGTFRLKDDVVIASVKTALELGYRAVDTAQIYDNEAAVGQAIAESG----VPRNE 58 Query: 302 LFITTKLW--NSDHGHVLEACKDSXXXXXXXXXXXXXIHFP 418 L+ITTK+W N ++ + K+S IH+P Sbjct: 59 LYITTKIWIENLSKDKLIPSLKESLKKLRTDYVDLTLIHWP 99
>DKGB_ECOLI (P30863) 2,5-diketo-D-gluconic acid reductase B (EC 1.1.1.274)| (2,5-DKG reductase B) (2,5-DKGR B) (25DKGR-B) (AKR5D) Length = 267 Score = 61.6 bits (148), Expect = 8e-10 Identities = 37/101 (36%), Positives = 52/101 (51%), Gaps = 2/101 (1%) Frame = +2 Query: 122 MPAVGLGVWRMDSPAVRGLIHSALRAGYRHFDCAADYKNEAEVGDALAEAFQTGLVKRED 301 +PA GLG +R+ V + +AL GYR D A Y NEA VG A+AE+ V R + Sbjct: 3 IPAFGLGTFRLKDDVVISSVITALELGYRAIDTAQIYDNEAAVGQAIAESG----VPRHE 58 Query: 302 LFITTKLW--NSDHGHVLEACKDSXXXXXXXXXXXXXIHFP 418 L+ITTK+W N ++ + K+S IH+P Sbjct: 59 LYITTKIWIENLSKDKLIPSLKESLQKLRTDYVDLTLIHWP 99
>DKGB_ECO57 (Q8X7Z7) 2,5-diketo-D-gluconic acid reductase B (EC 1.1.1.274)| (2,5-DKG reductase B) (2,5-DKGR B) (25DKGR-B) (AKR5D) Length = 267 Score = 60.8 bits (146), Expect = 1e-09 Identities = 37/101 (36%), Positives = 52/101 (51%), Gaps = 2/101 (1%) Frame = +2 Query: 122 MPAVGLGVWRMDSPAVRGLIHSALRAGYRHFDCAADYKNEAEVGDALAEAFQTGLVKRED 301 +PA GLG +R+ V + +AL GYR D A Y NEA VG A+AE+ V R + Sbjct: 3 IPAFGLGTFRLKDDVVISSVKTALELGYRAIDTAQIYDNEAAVGLAIAESG----VPRHE 58 Query: 302 LFITTKLW--NSDHGHVLEACKDSXXXXXXXXXXXXXIHFP 418 L+ITTK+W N ++ + K+S IH+P Sbjct: 59 LYITTKIWIENLSKDKLIPSLKESLQKLRTDYVDLTLIHWP 99
>CRO_RANCA (P17264) Rho crystallin| Length = 323 Score = 60.8 bits (146), Expect = 1e-09 Identities = 32/81 (39%), Positives = 43/81 (53%), Gaps = 3/81 (3%) Frame = +2 Query: 92 TATALSSGHEMPAVGLGVWRM-DSPA--VRGLIHSALRAGYRHFDCAADYKNEAEVGDAL 262 T L+ G+ MP +GLG + D P + +A+ GYRH DCA NE +G+ + Sbjct: 6 TRVTLNDGNMMPILGLGTYAAPDVPKSLAEEAVKTAIDVGYRHIDCAFITGNEMHIGNGI 65 Query: 263 AEAFQTGLVKREDLFITTKLW 325 G VKRED+F T KLW Sbjct: 66 RSKISDGTVKREDIFYTGKLW 86
>NADO2_ORYSA (Q7G765) Probable NAD(P)H-dependent oxidoreductase 2 (EC 1.-.-.-)| Length = 322 Score = 60.5 bits (145), Expect = 2e-09 Identities = 41/122 (33%), Positives = 56/122 (45%), Gaps = 3/122 (2%) Frame = +2 Query: 62 PATDRLGMAATATALSSGHEMPAVGLGVWRMDSPAVRGLIHSALRAGYRHFDCAADYKNE 241 P R+GM A +S E A L A+ GYRHFD A Y E Sbjct: 16 PTMPRIGMGTAAFPFTSSEETTAALL---------------RAIELGYRHFDTARLYATE 60 Query: 242 AEVGDALAEAFQTGLV-KREDLFITTKLWNSD--HGHVLEACKDSXXXXXXXXXXXXXIH 412 V +A+AEA + GLV R D+F+T+KLW SD G V+ A +++ +H Sbjct: 61 GCVSEAVAEAVRRGLVASRADVFVTSKLWCSDLHAGRVVPAARETLRNLGMDYVDLLLVH 120 Query: 413 FP 418 +P Sbjct: 121 WP 122
>PGFS1_BOVIN (P05980) Prostaglandin-F synthase 1 (EC 1.1.1.188) (PGF synthase 1)| (PGF 1) (Prostaglandin-D2 11 reductase 1) (PGFSI) Length = 323 Score = 60.5 bits (145), Expect = 2e-09 Identities = 38/114 (33%), Positives = 56/114 (49%), Gaps = 5/114 (4%) Frame = +2 Query: 104 LSSGHEMPAVGLGVWRMDSPAVRGLIHS---ALRAGYRHFDCAADYKNEAEVGDALAEAF 274 L+ GH +P +G G + + + + A+ G+RH D A Y+NE +VG A+ Sbjct: 10 LNDGHFIPVLGFGTYAPEEVPKSEALEATKFAIEVGFRHVDSAHLYQNEEQVGQAIRSKI 69 Query: 275 QTGLVKREDLFITTKLW-NSDHGHVLE-ACKDSXXXXXXXXXXXXXIHFPVATK 430 G VKRED+F T+KLW NS ++ A + S IH PV+ K Sbjct: 70 ADGTVKREDIFYTSKLWCNSLQPELVRPALEKSLQNLQLDYVDLYIIHSPVSLK 123
>CRO_RANTE (P02532) Rho crystallin| Length = 323 Score = 60.1 bits (144), Expect = 2e-09 Identities = 30/81 (37%), Positives = 41/81 (50%), Gaps = 3/81 (3%) Frame = +2 Query: 92 TATALSSGHEMPAVGLGVW---RMDSPAVRGLIHSALRAGYRHFDCAADYKNEAEVGDAL 262 T L+ G+ MP +GLG + + + A+ GYRH DCA NE +G+ + Sbjct: 6 TRVTLNDGNMMPILGLGTYASPHVPKSLAEEAVKIAIDVGYRHIDCAFITGNEMHIGNGI 65 Query: 263 AEAFQTGLVKREDLFITTKLW 325 G VKRED+F T KLW Sbjct: 66 RSKISDGTVKREDIFYTGKLW 86
>DKGB_YERPE (Q8ZH36) 2,5-diketo-D-gluconic acid reductase B (EC 1.1.1.274)| (2,5-DKG reductase B) (2,5-DKGR B) (25DKGR-B) (AKR5D) Length = 267 Score = 59.3 bits (142), Expect = 4e-09 Identities = 34/101 (33%), Positives = 51/101 (50%), Gaps = 2/101 (1%) Frame = +2 Query: 122 MPAVGLGVWRMDSPAVRGLIHSALRAGYRHFDCAADYKNEAEVGDALAEAFQTGLVKRED 301 +P GLG +R+ V + AL GYR D A Y+NEA VG A+ E+ + R++ Sbjct: 3 IPVFGLGTFRLQDQIVIDSVSQALTLGYRAIDTAQIYENEAPVGQAIQESG----INRDE 58 Query: 302 LFITTKLW--NSDHGHVLEACKDSXXXXXXXXXXXXXIHFP 418 LFITTK+W N ++ + ++S IH+P Sbjct: 59 LFITTKIWIANLSKDKLIPSLRESIQKLKTDYVDLTLIHWP 99
>PGFS2_BOVIN (P52897) Prostaglandin-F synthase 2 (EC 1.1.1.188) (PGF synthase 2)| (PGF 2) (Prostaglandin-D2 11 reductase 2) (PGFSII) Length = 323 Score = 58.9 bits (141), Expect = 5e-09 Identities = 37/113 (32%), Positives = 55/113 (48%), Gaps = 5/113 (4%) Frame = +2 Query: 107 SSGHEMPAVGLGVWRMDSPAVRGLIHS---ALRAGYRHFDCAADYKNEAEVGDALAEAFQ 277 + GH +P +G G + + + + A+ G+RH D A Y+NE +VG A+ Sbjct: 11 NDGHFIPVLGFGTYAPEEVPKSEALEATKFAIEVGFRHVDSAHLYQNEEQVGQAIRSKIA 70 Query: 278 TGLVKREDLFITTKLW-NSDHGHVLE-ACKDSXXXXXXXXXXXXXIHFPVATK 430 G VKRED+F T+KLW NS ++ A + S IH PV+ K Sbjct: 71 DGTVKREDIFYTSKLWCNSLQPELVRPALEKSLQNLQLDYVDLYIIHSPVSLK 123
>YOF5_CAEEL (Q09632) Probable oxidoreductase ZK1290.5 in chromosome II (EC| 1.-.-.-) Length = 321 Score = 52.8 bits (125), Expect = 4e-07 Identities = 36/108 (33%), Positives = 49/108 (45%), Gaps = 1/108 (0%) Frame = +2 Query: 98 TALSSGHEMPAVGLGVWRMDSPAVRGLIHSALRAGYRHFDCAADYKNEAEVGDALAEAFQ 277 T LS+ EMP +GLG ++HS + GYR D A Y E ++G A+ Sbjct: 5 TVLSNNVEMPLIGLGTTHSGGYYHDAVLHSIKKCGYRLIDTAKRYGVEKQLGIAVKNC-- 62 Query: 278 TGLVKREDLFITTKLWNSDHG-HVLEACKDSXXXXXXXXXXXXXIHFP 418 V RE++F++TKLW D G V A + S IH P Sbjct: 63 --SVPREEMFLSTKLWPVDCGDEVYNAFQTSCEKLQTDYLDMYMIHMP 108
>AFR_PIG (P82125) 1,5-anhydro-D-fructose reductase (EC 1.1.1.263) (AF| reductase) (Fragments) Length = 206 Score = 52.4 bits (124), Expect = 5e-07 Identities = 28/68 (41%), Positives = 38/68 (55%), Gaps = 1/68 (1%) Frame = +2 Query: 119 EMPAVGLGVWRM-DSPAVRGLIHSALRAGYRHFDCAADYKNEAEVGDALAEAFQTGLVKR 295 ++P +GLG W+ V + A+ GYRH D A Y NE EVG + G+V+R Sbjct: 1 KIPVLGLGTWQAAPGGEVTEAVKVAIDTGYRHPDSAYLYHNEDEVGVGIQAKIDEGVVRR 60 Query: 296 EDLFITTK 319 EDLFI +K Sbjct: 61 EDLFIVSK 68
>DKGB_CORSS (P15339) 2,5-diketo-D-gluconic acid reductase B (EC 1.1.1.274)| (2,5-DKG reductase B) (2,5-DKGR B) (25DKGR-B) (AKR5D) Length = 276 Score = 45.1 bits (105), Expect = 8e-05 Identities = 28/108 (25%), Positives = 50/108 (46%), Gaps = 2/108 (1%) Frame = +2 Query: 101 ALSSGHEMPAVGLGVWRMDSPAVRGLIHSALRAGYRHFDCAADYKNEAEVGDALAEAFQT 280 +L+ G GLG + + + +A+ +GYR D A +Y+NE+EVG A + Sbjct: 7 SLNDGRPFAEPGLGTYNLRGDEGVAAMVAAIDSGYRLLDTAVNYENESEVG----RAVRA 62 Query: 281 GLVKREDLFITTKLWNSDHG--HVLEACKDSXXXXXXXXXXXXXIHFP 418 V R++L + +K+ HG +++ + S IH+P Sbjct: 63 SSVDRDELIVASKIPGRQHGRAEAVDSIRGSLDRLGLDVIDLQLIHWP 110
>YEAE_ECOLI (P76234) Hypothetical protein yeaE| Length = 284 Score = 34.7 bits (78), Expect = 0.10 Identities = 32/92 (34%), Positives = 45/92 (48%), Gaps = 10/92 (10%) Frame = +2 Query: 122 MPAVGLGVWRM-DSPAVRGLIHSALRAGYR-------HFDCAADYKNEAEVGDALAEAFQ 277 +PAVG G W M + + R +ALRAG + AD E VG+AL Sbjct: 14 LPAVGQGTWYMGEDASQRKTEVAALRAGIELGLTLIDTAEMYADGGAEKVVGEAL----- 68 Query: 278 TGLVKREDLFITTKL--WNSDHGHVLEACKDS 367 TGL RE +F+ +K+ WN+ + AC+ S Sbjct: 69 TGL--REKVFLVSKVYPWNAGGQKAINACEAS 98
>YGHZ_ECOLI (Q46851) Hypothetical protein yghZ| Length = 346 Score = 34.7 bits (78), Expect = 0.10 Identities = 29/104 (27%), Positives = 42/104 (40%), Gaps = 14/104 (13%) Frame = +2 Query: 71 DRLGMAATATALSSGHEMPAVGLGVWRMDS-----PAVRGLIHSALRAGYRHFDCAADY- 232 +R G SG +PA+ LG+W + R ++ A G HFD A +Y Sbjct: 8 ERYGQMQYRYCGKSGLRLPALSLGLWHNFGHVNALESQRAILRKAFDLGITHFDLANNYG 67 Query: 233 ----KNEAEVGDALAEAFQTGLVKREDLFITTK----LWNSDHG 340 E G L E F R++L I+TK +W +G Sbjct: 68 PPPGSAEENFGRLLREDF---AAYRDELIISTKAGYDMWPGPYG 108
>YGHZ_ECO57 (Q8X529) Hypothetical protein yghZ| Length = 346 Score = 34.7 bits (78), Expect = 0.10 Identities = 29/104 (27%), Positives = 42/104 (40%), Gaps = 14/104 (13%) Frame = +2 Query: 71 DRLGMAATATALSSGHEMPAVGLGVWRMDS-----PAVRGLIHSALRAGYRHFDCAADY- 232 +R G SG +PA+ LG+W + R ++ A G HFD A +Y Sbjct: 8 ERYGQMQYRYCGKSGLRLPALSLGLWHNFGHVNALESQRAILRKAFDLGITHFDLANNYG 67 Query: 233 ----KNEAEVGDALAEAFQTGLVKREDLFITTK----LWNSDHG 340 E G L E F R++L I+TK +W +G Sbjct: 68 PPPGSAEENFGRLLREDF---AAYRDELIISTKAGYDMWPGPYG 108
>ATG9_ASPFU (Q4WLT9) Autophagy-related protein 9| Length = 951 Score = 29.3 bits (64), Expect = 4.3 Identities = 14/42 (33%), Positives = 27/42 (64%) Frame = +2 Query: 194 RAGYRHFDCAADYKNEAEVGDALAEAFQTGLVKREDLFITTK 319 RAG D ++ ++ E+ DA+A+A ++ L+ R+D FI+ + Sbjct: 38 RAGLTLEDGPGEHYSDRELEDAMADAGRSRLLDRDDAFISRR 79
>POL_SIVVG (P27980) Pol polyprotein [Contains: Protease (Retropepsin) (EC| 3.4.23.-); Reverse transcriptase/ribonuclease H (EC 2.7.7.49) (EC 3.1.26.4) (RT); Integrase (IN)] Length = 1046 Score = 28.9 bits (63), Expect = 5.7 Identities = 18/49 (36%), Positives = 25/49 (51%) Frame = -2 Query: 433 MLSSYREVNKVEIKIIQSQLLQAVLAGFKHMTMI*VPQLGSDEKILPLD 287 ML +RE+NK + QL +GF+ MT I V +G +PLD Sbjct: 269 MLVDFRELNKATQDFFEVQLGIPHPSGFEKMTEITVLDIGDAYYSIPLD 317 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 45,379,372 Number of Sequences: 219361 Number of extensions: 745556 Number of successful extensions: 2611 Number of sequences better than 10.0: 87 Number of HSP's better than 10.0 without gapping: 2519 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 2567 length of database: 80,573,946 effective HSP length: 101 effective length of database: 58,418,485 effective search space used: 2511994855 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
