ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | bart35h11 |
|---|---|
| Clone Library Name | barley_pub |
>NADO1_ORYSA (Q7G764) Probable NAD(P)H-dependent oxidoreductase 1 (EC 1.1.1.-)| Length = 321 Score = 133 bits (335), Expect = 2e-31 Identities = 70/145 (48%), Positives = 84/145 (57%), Gaps = 2/145 (1%) Frame = +1 Query: 64 STQPMGAGDRTVAGMPRIGMGTAV-QGPKPDPIRRAVLRAIEIGYRHFDTAAHYETEAPI 240 +T P + MPR+GMGTA + A+LRAIE+GYRHFDTA Y TE + Sbjct: 2 ATIPEVPASELIQTMPRVGMGTAAFPFTSSEDTTAAMLRAIELGYRHFDTARIYATEGCV 61 Query: 241 XXXXXXXXXXXXXXXXDDLFITSKLWCSDAHGDRVVPALRHTLRNLQMEYVDLYLVHWPV 420 D+F+TSK+WCSD H RVVPA R TLRNL M+YVDL LVHWPV Sbjct: 62 GEAVAEAVRRGLIASRADVFVTSKIWCSDLHAGRVVPAARETLRNLGMDYVDLLLVHWPV 121 Query: 421 SMKPGRFKAPFTAEDFVP-FDMRAV 492 S+ PG + PF E +P FDM V Sbjct: 122 SLTPGNYDFPFPKEVILPSFDMEGV 146
>NADO2_ORYSA (Q7G765) Probable NAD(P)H-dependent oxidoreductase 2 (EC 1.-.-.-)| Length = 322 Score = 132 bits (331), Expect = 7e-31 Identities = 68/131 (51%), Positives = 79/131 (60%), Gaps = 2/131 (1%) Frame = +1 Query: 106 MPRIGMGTAV-QGPKPDPIRRAVLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXXXXX 282 MPRIGMGTA + A+LRAIE+GYRHFDTA Y TE + Sbjct: 18 MPRIGMGTAAFPFTSSEETTAALLRAIELGYRHFDTARLYATEGCVSEAVAEAVRRGLVA 77 Query: 283 XXDDLFITSKLWCSDAHGDRVVPALRHTLRNLQMEYVDLYLVHWPVSMKPGRFKAPFTAE 462 D+F+TSKLWCSD H RVVPA R TLRNL M+YVDL LVHWP ++ PG + PF E Sbjct: 78 SRADVFVTSKLWCSDLHAGRVVPAARETLRNLGMDYVDLLLVHWPATVAPGSYDFPFPKE 137 Query: 463 DFVP-FDMRAV 492 + P FDM V Sbjct: 138 EMAPAFDMEGV 148
>6DCS_SOYBN (P26690) NAD(P)H dependent 6'-deoxychalcone synthase (EC 2.3.1.170)| Length = 315 Score = 120 bits (301), Expect = 2e-27 Identities = 61/159 (38%), Positives = 91/159 (57%) Frame = +1 Query: 16 ASESQLPTQPFPSHTPSTQPMGAGDRTVAGMPRIGMGTAVQGPKPDPIRRAVLRAIEIGY 195 A+ ++PT FP+ + + MP +GMG+A + A++ A++ GY Sbjct: 2 AAAIEIPTIVFPNSSAQQR-----------MPVVGMGSAPDFTCKKDTKEAIIEAVKQGY 50 Query: 196 RHFDTAAHYETEAPIXXXXXXXXXXXXXXXXDDLFITSKLWCSDAHGDRVVPALRHTLRN 375 RHFDTAA Y +E + DLF+TSKLW ++ H V+PALR +L+ Sbjct: 51 RHFDTAAAYGSEQALGEALKEAIHLGLVSR-QDLFVTSKLWVTENHPHLVLPALRKSLKT 109 Query: 376 LQMEYVDLYLVHWPVSMKPGRFKAPFTAEDFVPFDMRAV 492 LQ+EY+DLYL+HWP+S +PG+F P ED +PFD++ V Sbjct: 110 LQLEYLDLYLIHWPLSSQPGKFSFPIEVEDLLPFDVKGV 148
>AK1A1_PIG (P50578) Alcohol dehydrogenase [NADP+] (EC 1.1.1.2) (Aldehyde| reductase) (Aldo-keto reductase family 1 member A1) Length = 324 Score = 94.4 bits (233), Expect = 2e-19 Identities = 49/125 (39%), Positives = 70/125 (56%) Frame = +1 Query: 106 MPRIGMGTAVQGPKPDPIRRAVLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXXXXXX 285 MP IG+GT +P ++ A+ A+ +GYRH D AA Y E I Sbjct: 13 MPLIGLGTWKS--EPGQVKAAIKYALTVGYRHIDCAAIYGNELEIGEALTETVGPGKAVP 70 Query: 286 XDDLFITSKLWCSDAHGDRVVPALRHTLRNLQMEYVDLYLVHWPVSMKPGRFKAPFTAED 465 ++LF+TSKLW + H + V PALR TL +LQ+EY+DLYL+HWP + + G P A+ Sbjct: 71 REELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADG 130 Query: 466 FVPFD 480 + +D Sbjct: 131 TIRYD 135
>AK1A1_RAT (P51635) Alcohol dehydrogenase [NADP+] (EC 1.1.1.2) (Aldehyde| reductase) (Aldo-keto reductase family 1 member A1) (3-DG-reducing enzyme) Length = 324 Score = 94.0 bits (232), Expect = 2e-19 Identities = 48/125 (38%), Positives = 70/125 (56%) Frame = +1 Query: 106 MPRIGMGTAVQGPKPDPIRRAVLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXXXXXX 285 MP IG+GT +P ++ A+ A+ +GYRH D A+ Y E I Sbjct: 13 MPLIGLGTWKS--EPGQVKAAIKYALSVGYRHIDCASVYGNETEIGEALKESVGAGKAVP 70 Query: 286 XDDLFITSKLWCSDAHGDRVVPALRHTLRNLQMEYVDLYLVHWPVSMKPGRFKAPFTAED 465 ++LF+TSKLW + H + V PA+R TL +LQ+EY+DLYL+HWP + + G P A+ Sbjct: 71 REELFVTSKLWNTKHHPEDVEPAVRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADG 130 Query: 466 FVPFD 480 V +D Sbjct: 131 TVKYD 135
>AK1A1_MOUSE (Q9JII6) Alcohol dehydrogenase [NADP+] (EC 1.1.1.2) (Aldehyde| reductase) (Aldo-keto reductase family 1 member A1) Length = 324 Score = 94.0 bits (232), Expect = 2e-19 Identities = 49/125 (39%), Positives = 69/125 (55%) Frame = +1 Query: 106 MPRIGMGTAVQGPKPDPIRRAVLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXXXXXX 285 MP IG+GT +P ++ A+ A+ GYRH D A+ Y E I Sbjct: 13 MPLIGLGTWKS--EPGQVKAAIKHALSAGYRHIDCASVYGNETEIGEALKESVGSGKAVP 70 Query: 286 XDDLFITSKLWCSDAHGDRVVPALRHTLRNLQMEYVDLYLVHWPVSMKPGRFKAPFTAED 465 ++LF+TSKLW + H + V PALR TL +LQ+EY+DLYL+HWP + + G P A+ Sbjct: 71 REELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADG 130 Query: 466 FVPFD 480 V +D Sbjct: 131 TVRYD 135
>AK1A1_HUMAN (P14550) Alcohol dehydrogenase [NADP+] (EC 1.1.1.2) (Aldehyde| reductase) (Aldo-keto reductase family 1 member A1) Length = 324 Score = 94.0 bits (232), Expect = 2e-19 Identities = 50/125 (40%), Positives = 70/125 (56%) Frame = +1 Query: 106 MPRIGMGTAVQGPKPDPIRRAVLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXXXXXX 285 MP IG+GT +P ++ AV A+ +GYRH D AA Y E I Sbjct: 13 MPLIGLGTWKS--EPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPGKAVP 70 Query: 286 XDDLFITSKLWCSDAHGDRVVPALRHTLRNLQMEYVDLYLVHWPVSMKPGRFKAPFTAED 465 ++LF+TSKLW + H + V PALR TL +LQ+EY+DLYL+HWP + + G P A+ Sbjct: 71 REELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADG 130 Query: 466 FVPFD 480 + +D Sbjct: 131 TICYD 135
>ALDR_HORVU (P23901) Aldose reductase (EC 1.1.1.21) (AR) (Aldehyde reductase)| Length = 320 Score = 91.7 bits (226), Expect = 1e-18 Identities = 51/130 (39%), Positives = 71/130 (54%), Gaps = 1/130 (0%) Frame = +1 Query: 106 MPRIGMGTAVQGPKP-DPIRRAVLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXXXXX 282 MP +G+GT G +R A+ A GYRH DTAA Y E + Sbjct: 24 MPAVGLGTWRAGSDTAHSVRTAITEA---GYRHVDTAAEYGVEKEVGKGLKAAMEAGIDR 80 Query: 283 XXDDLFITSKLWCSDAHGDRVVPALRHTLRNLQMEYVDLYLVHWPVSMKPGRFKAPFTAE 462 DLF+TSK+WC++ +RV PAL +TL++LQ++Y+DLY +HWP +K G P A Sbjct: 81 K--DLFVTSKIWCTNLAPERVRPALENTLKDLQLDYIDLYHIHWPFRLKDGAHMPP-EAG 137 Query: 463 DFVPFDMRAV 492 + + FDM V Sbjct: 138 EVLEFDMEGV 147
>ALDR_PIG (P80276) Aldose reductase (EC 1.1.1.21) (AR) (Aldehyde reductase)| Length = 315 Score = 88.2 bits (217), Expect = 1e-17 Identities = 48/123 (39%), Positives = 67/123 (54%) Frame = +1 Query: 94 TVAGMPRIGMGTAVQGPKPDPIRRAVLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXX 273 T A MP +G+GT P + AV AI++GYRH D A Y+ E + Sbjct: 8 TGAKMPILGLGTWKS--PPGKVTEAVKVAIDLGYRHIDCAHVYQNENEVGLGLQEKLQGQ 65 Query: 274 XXXXXDDLFITSKLWCSDAHGDRVVPALRHTLRNLQMEYVDLYLVHWPVSMKPGRFKAPF 453 +DLFI SKLWC+D + V A + TLR+L+++Y+DLYL+HWP KPG+ P Sbjct: 66 VVKR-EDLFIVSKLWCTDHEKNLVKGACQTTLRDLKLDYLDLYLIHWPTGFKPGKDPFPL 124 Query: 454 TAE 462 + Sbjct: 125 DGD 127
>AK1C1_PONPY (Q5REQ0) Aldo-keto reductase family 1 member C1 homolog (EC| 1.-.-.-) (20-alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.149) (20-alpha-HSD) Length = 323 Score = 88.2 bits (217), Expect = 1e-17 Identities = 51/127 (40%), Positives = 68/127 (53%), Gaps = 2/127 (1%) Frame = +1 Query: 106 MPRIGMGTAV--QGPKPDPIRRAVLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXXXX 279 MP +G GT + PK + L AIE G+RH D+A Y E + Sbjct: 16 MPVLGFGTYAPPEVPKSKALEATKL-AIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSV 74 Query: 280 XXXDDLFITSKLWCSDAHGDRVVPALRHTLRNLQMEYVDLYLVHWPVSMKPGRFKAPFTA 459 +D+F TSKLWC+ + V PAL +L+NLQ++YVDLYLVH+PVS+KPG P Sbjct: 75 KR-EDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLVHFPVSVKPGEEVIPKDE 133 Query: 460 EDFVPFD 480 + FD Sbjct: 134 NGKILFD 140
>AK1C1_HUMAN (Q04828) Aldo-keto reductase family 1 member C1 (EC 1.1.1.-)| (20-alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.149) (20-alpha-HSD) (Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase) (EC 1.3.1.20) (High-affinity hepatic bile acid-binding protei Length = 323 Score = 88.2 bits (217), Expect = 1e-17 Identities = 49/126 (38%), Positives = 65/126 (51%), Gaps = 1/126 (0%) Frame = +1 Query: 106 MPRIGMGTAVQGPKP-DPIRRAVLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXXXXX 282 MP +G GT P A AIE G+RH D+A Y E + Sbjct: 16 MPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVK 75 Query: 283 XXDDLFITSKLWCSDAHGDRVVPALRHTLRNLQMEYVDLYLVHWPVSMKPGRFKAPFTAE 462 +D+F TSKLWC+ + V PAL +L+NLQ++YVDLYL+H+PVS+KPG P Sbjct: 76 R-EDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDEN 134 Query: 463 DFVPFD 480 + FD Sbjct: 135 GKILFD 140
>AK1C1_MACFU (Q95JH6) Aldo-keto reductase family 1 member C1 homolog (EC| 1.-.-.-) (20-alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.149) (20-alpha-HSD) (Dihydrodiol dehydrogenase 1) (DD-1) (DD1) Length = 323 Score = 87.0 bits (214), Expect = 2e-17 Identities = 51/127 (40%), Positives = 68/127 (53%), Gaps = 2/127 (1%) Frame = +1 Query: 106 MPRIGMGT--AVQGPKPDPIRRAVLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXXXX 279 MP +G GT + PK I L AIE G+RH D+A Y E + Sbjct: 16 MPVLGFGTYAPAEVPKNKAIEATKL-AIEAGFRHIDSAHLYNNEEYVGLAIRSKIADGTV 74 Query: 280 XXXDDLFITSKLWCSDAHGDRVVPALRHTLRNLQMEYVDLYLVHWPVSMKPGRFKAPFTA 459 +D+F TSKLWC+ + V PAL +L+NLQ++YVDLYL+H+PVS+KPG P Sbjct: 75 KR-EDIFYTSKLWCNSHRPEFVRPALERSLKNLQLDYVDLYLIHFPVSLKPGEELIPKDE 133 Query: 460 EDFVPFD 480 + FD Sbjct: 134 NGKLLFD 140
>AK1C1_MACFA (Q95JH7) Aldo-keto reductase family 1 member C1 homolog (EC| 1.-.-.-) (20-alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.149) (20-alpha-HSD) (Dihydrodiol dehydrogenase 1) (DD-1) (DD1) Length = 323 Score = 87.0 bits (214), Expect = 2e-17 Identities = 49/126 (38%), Positives = 66/126 (52%), Gaps = 1/126 (0%) Frame = +1 Query: 106 MPRIGMGTAVQGPKP-DPIRRAVLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXXXXX 282 MP +G GT P + A AIE G+RH D+A Y E + Sbjct: 16 MPVLGFGTYAPAEVPKNKALEATKLAIEAGFRHIDSAHLYNNEEYVGLAIRSKIADGTVK 75 Query: 283 XXDDLFITSKLWCSDAHGDRVVPALRHTLRNLQMEYVDLYLVHWPVSMKPGRFKAPFTAE 462 +D+F TSKLWC+ + V PAL +L+NLQ++YVDLYL+H+PVS+KPG P Sbjct: 76 R-EDIFYTSKLWCNSHRPEFVRPALERSLKNLQLDYVDLYLIHFPVSLKPGEELIPKDEN 134 Query: 463 DFVPFD 480 + FD Sbjct: 135 GKLLFD 140
>ALDR_BOVIN (P16116) Aldose reductase (EC 1.1.1.21) (AR) (Aldehyde reductase)| (20-alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.149) (20-alpha-HSD) Length = 315 Score = 86.3 bits (212), Expect = 4e-17 Identities = 50/129 (38%), Positives = 67/129 (51%) Frame = +1 Query: 94 TVAGMPRIGMGTAVQGPKPDPIRRAVLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXX 273 T A MP +G+GT P + AV AI++GYRH D A Y+ E + Sbjct: 8 TGAKMPILGLGTWKS--PPGKVTEAVKVAIDLGYRHIDCAHVYQNENEVGLALQAKLQEQ 65 Query: 274 XXXXXDDLFITSKLWCSDAHGDRVVPALRHTLRNLQMEYVDLYLVHWPVSMKPGRFKAPF 453 +DLFI SKLWC+ D V A + TL +L+++Y+DLYL+HWP KPG+ Sbjct: 66 VVKR-EDLFIVSKLWCTYHDKDLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK----- 119 Query: 454 TAEDFVPFD 480 DF P D Sbjct: 120 ---DFFPLD 125
>S6PD_MALDO (P28475) NADP-dependent D-sorbitol-6-phosphate dehydrogenase (EC| 1.1.1.200) (Aldose-6-phosphate reductase [NADPH]) (NADP-S6PDH) Length = 310 Score = 85.5 bits (210), Expect = 7e-17 Identities = 47/108 (43%), Positives = 69/108 (63%) Frame = +1 Query: 106 MPRIGMGTAVQGPKPDPIRRAVLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXXXXXX 285 MP IG+G + + D ++ +L AI+IGYRHFD AAHY++EA + Sbjct: 12 MPVIGLG--LWRLEKDELKEVILNAIKIGYRHFDCAAHYKSEADV-GEALAEAFKTGLVK 68 Query: 286 XDDLFITSKLWCSDAHGDRVVPALRHTLRNLQMEYVDLYLVHWPVSMK 429 ++LFIT+K+W SD HG VV A +++L LQ++Y+DLYLVH+P+ K Sbjct: 69 REELFITTKIWNSD-HG-HVVEACKNSLEKLQIDYLDLYLVHYPMPTK 114
>PGFS2_BOVIN (P52897) Prostaglandin-F synthase 2 (EC 1.1.1.188) (PGF synthase 2)| (PGF 2) (Prostaglandin-D2 11 reductase 2) (PGFSII) Length = 323 Score = 85.5 bits (210), Expect = 7e-17 Identities = 48/127 (37%), Positives = 70/127 (55%), Gaps = 2/127 (1%) Frame = +1 Query: 106 MPRIGMGTAV--QGPKPDPIRRAVLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXXXX 279 +P +G GT + PK + + A AIE+G+RH D+A Y+ E + Sbjct: 16 IPVLGFGTYAPEEVPKSEALE-ATKFAIEVGFRHVDSAHLYQNEEQVGQAIRSKIADGTV 74 Query: 280 XXXDDLFITSKLWCSDAHGDRVVPALRHTLRNLQMEYVDLYLVHWPVSMKPGRFKAPFTA 459 +D+F TSKLWC+ + V PAL +L+NLQ++YVDLY++H PVS+KPG P Sbjct: 75 KR-EDIFYTSKLWCNSLQPELVRPALEKSLQNLQLDYVDLYIIHSPVSLKPGNKFVPKDE 133 Query: 460 EDFVPFD 480 + FD Sbjct: 134 SGKLIFD 140
>PGFS1_BOVIN (P05980) Prostaglandin-F synthase 1 (EC 1.1.1.188) (PGF synthase 1)| (PGF 1) (Prostaglandin-D2 11 reductase 1) (PGFSI) Length = 323 Score = 85.5 bits (210), Expect = 7e-17 Identities = 48/127 (37%), Positives = 70/127 (55%), Gaps = 2/127 (1%) Frame = +1 Query: 106 MPRIGMGTAV--QGPKPDPIRRAVLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXXXX 279 +P +G GT + PK + + A AIE+G+RH D+A Y+ E + Sbjct: 16 IPVLGFGTYAPEEVPKSEALE-ATKFAIEVGFRHVDSAHLYQNEEQVGQAIRSKIADGTV 74 Query: 280 XXXDDLFITSKLWCSDAHGDRVVPALRHTLRNLQMEYVDLYLVHWPVSMKPGRFKAPFTA 459 +D+F TSKLWC+ + V PAL +L+NLQ++YVDLY++H PVS+KPG P Sbjct: 75 KR-EDIFYTSKLWCNSLQPELVRPALEKSLQNLQLDYVDLYIIHSPVSLKPGNKFVPKDE 133 Query: 460 EDFVPFD 480 + FD Sbjct: 134 SGKLIFD 140
>AK1A1_CRIGR (O70473) Alcohol dehydrogenase [NADP+] (EC 1.1.1.2) (Aldehyde| reductase) (Aldo-keto reductase family 1 member A1) (Fragment) Length = 228 Score = 84.3 bits (207), Expect = 2e-16 Identities = 45/122 (36%), Positives = 65/122 (53%) Frame = +1 Query: 115 IGMGTAVQGPKPDPIRRAVLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXXXXXXXDD 294 IG+GT P ++ A+ A+ +GYRH D AA Y E I ++ Sbjct: 2 IGLGTWKSNP--GQVKAAIKYALSVGYRHIDCAAVYGNEIEIGEALKENVGPGKAVPREE 59 Query: 295 LFITSKLWCSDAHGDRVVPALRHTLRNLQMEYVDLYLVHWPVSMKPGRFKAPFTAEDFVP 474 LF+TSKLW + H + V ALR TL +LQ+EY+DLYL+HWP + + G P + + Sbjct: 60 LFVTSKLWNTKHHPEDVEAALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNDDGTIR 119 Query: 475 FD 480 +D Sbjct: 120 YD 121
>AK1CD_MOUSE (Q8VC28) Aldo-keto reductase family 1 member C13 (EC 1.1.1.-)| Length = 323 Score = 84.0 bits (206), Expect = 2e-16 Identities = 46/112 (41%), Positives = 65/112 (58%), Gaps = 2/112 (1%) Frame = +1 Query: 106 MPRIGMGT--AVQGPKPDPIRRAVLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXXXX 279 +P +G GT + PK + A L A+++GYRH DTA Y+ E I Sbjct: 16 IPALGFGTYKPKEVPKSKSLEAACL-ALDVGYRHVDTAYAYQVEEEIGQAIQSKIKAGVV 74 Query: 280 XXXDDLFITSKLWCSDAHGDRVVPALRHTLRNLQMEYVDLYLVHWPVSMKPG 435 +DLFIT+KLWC+ + V PAL +L+ LQ++YVDLY++H+PV MK G Sbjct: 75 KR-EDLFITTKLWCTCFRPELVKPALEKSLKKLQLDYVDLYIMHYPVPMKSG 125
>AK1C2_HUMAN (P52895) Aldo-keto reductase family 1 member C2 (EC 1.-.-.-)| (Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase) (EC 1.3.1.20) (Type III 3-alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.213) (3-alpha-HSD3) (Chlordecone reductase homolog HAKRD) ( Length = 323 Score = 84.0 bits (206), Expect = 2e-16 Identities = 48/126 (38%), Positives = 64/126 (50%), Gaps = 1/126 (0%) Frame = +1 Query: 106 MPRIGMGTAVQGPKP-DPIRRAVLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXXXXX 282 MP +G GT P AV AIE G+ H D+A Y E + Sbjct: 16 MPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRSKIADGSVK 75 Query: 283 XXDDLFITSKLWCSDAHGDRVVPALRHTLRNLQMEYVDLYLVHWPVSMKPGRFKAPFTAE 462 +D+F TSKLW + + V PAL +L+NLQ++YVDLYL+H+PVS+KPG P Sbjct: 76 R-EDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDEN 134 Query: 463 DFVPFD 480 + FD Sbjct: 135 GKILFD 140
>ALDR_MOUSE (P45376) Aldose reductase (EC 1.1.1.21) (AR) (Aldehyde reductase)| Length = 315 Score = 83.6 bits (205), Expect = 3e-16 Identities = 48/126 (38%), Positives = 64/126 (50%), Gaps = 1/126 (0%) Frame = +1 Query: 106 MPRIGMGTAVQGPKPDPIRRAVLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXXXXXX 285 MP +G+GT P + AV AI++GYRH D A Y+ E + Sbjct: 12 MPTLGLGTWKS--PPGQVTEAVKVAIDLGYRHIDCAQVYQNEKEVGVALQEKLKEQVVKR 69 Query: 286 XDDLFITSKLWCSDAHGDRVVPALRHTLRNLQMEYVDLYLVHWPVSMKPGRFKAPFTAE- 462 DLFI SKLWC+ V A + TL +LQ++Y+DLYL+HWP KPG P A Sbjct: 70 -QDLFIVSKLWCTFHDKSMVKGAFQKTLSDLQLDYLDLYLIHWPTGFKPGPDYFPLDASG 128 Query: 463 DFVPFD 480 + +P D Sbjct: 129 NVIPSD 134
>AK1C4_HUMAN (P17516) Aldo-keto reductase family 1 member C4 (EC 1.1.1.-)| (Chlordecone reductase) (EC 1.1.1.225) (CDR) (3-alpha-hydroxysteroid dehydrogenase type I) (EC 1.1.1.50) (3-alpha-HSD1) (Dihydrodiol dehydrogenase 4) (DD4) (HAKRA) Length = 323 Score = 83.6 bits (205), Expect = 3e-16 Identities = 50/128 (39%), Positives = 66/128 (51%), Gaps = 3/128 (2%) Frame = +1 Query: 106 MPRIGMGTAVQGPKPDPIRRAV---LRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXXX 276 MP +G GT P P RAV AIE G+RH D+A Y E + Sbjct: 16 MPVLGFGT--YAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSKIADGS 73 Query: 277 XXXXDDLFITSKLWCSDAHGDRVVPALRHTLRNLQMEYVDLYLVHWPVSMKPGRFKAPFT 456 +D+F TSKLWC+ V PAL +L+ LQ++YVDLYL+H+P+++KPG P Sbjct: 74 VKR-EDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGETPLPKD 132 Query: 457 AEDFVPFD 480 V FD Sbjct: 133 ENGKVIFD 140
>ALDR_RAT (P07943) Aldose reductase (EC 1.1.1.21) (AR) (Aldehyde reductase)| Length = 315 Score = 82.8 bits (203), Expect = 5e-16 Identities = 48/126 (38%), Positives = 64/126 (50%), Gaps = 1/126 (0%) Frame = +1 Query: 106 MPRIGMGTAVQGPKPDPIRRAVLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXXXXXX 285 MP +G+GT P + AV AI++GYRH D A Y+ E + Sbjct: 12 MPTLGLGTWKS--PPGQVTEAVKVAIDMGYRHIDCAQVYQNEKEVGVALQEKLKEQVVKR 69 Query: 286 XDDLFITSKLWCSDAHGDRVVPALRHTLRNLQMEYVDLYLVHWPVSMKPGRFKAPFTAE- 462 DLFI SKLWC+ V A + TL +LQ++Y+DLYL+HWP KPG P A Sbjct: 70 -QDLFIVSKLWCTFHDQSMVKGACQKTLSDLQLDYLDLYLIHWPTGFKPGPDYFPLDASG 128 Query: 463 DFVPFD 480 + +P D Sbjct: 129 NVIPSD 134
>AK1C4_MACFA (Q95JH5) Aldo-keto reductase family 1 member C4 (EC 1.1.1.-)| (Chlordecone reductase) (EC 1.1.1.225) (CDR) (3-alpha-hydroxysteroid dehydrogenase type I) (EC 1.1.1.50) (3-alpha-HSD1) (Dihydrodiol dehydrogenase 4) (DD4) (DD-4) Length = 323 Score = 82.8 bits (203), Expect = 5e-16 Identities = 49/128 (38%), Positives = 65/128 (50%), Gaps = 3/128 (2%) Frame = +1 Query: 106 MPRIGMGTAVQGPKPDPIRRAV---LRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXXX 276 MP +G GT P P R V AIE G+RH D+A Y E + Sbjct: 16 MPVLGFGT--YAPPEVPRNRVVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSKIADGS 73 Query: 277 XXXXDDLFITSKLWCSDAHGDRVVPALRHTLRNLQMEYVDLYLVHWPVSMKPGRFKAPFT 456 +D+F TSKLWC+ V PAL +L+ LQ++YVDLYL+H+P+++KPG P Sbjct: 74 VKR-EDIFYTSKLWCTFFRPQLVQPALESSLKKLQLDYVDLYLIHFPMALKPGETPLPKD 132 Query: 457 AEDFVPFD 480 V FD Sbjct: 133 ENGKVMFD 140
>YDG7_SCHPO (Q10494) Probable oxidoreductase C26F1.07 in chromosome I (EC| 1.-.-.-) Length = 321 Score = 82.4 bits (202), Expect = 6e-16 Identities = 46/116 (39%), Positives = 66/116 (56%), Gaps = 1/116 (0%) Frame = +1 Query: 106 MPRIGMGTAVQGPKPDPIRRAVLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXXXXXX 285 +P +G+GT +P+ + AV A++ GYRH D AA Y E + Sbjct: 24 IPGLGLGT--WRSEPNQTKNAVKTALQYGYRHIDAAAIYGNEDEVGDGIKESGVPRK--- 78 Query: 286 XDDLFITSKLWCSDAHGDRVVP-ALRHTLRNLQMEYVDLYLVHWPVSMKPGRFKAP 450 D+++TSKLWC+ AH VP AL TL++L+++Y+D YL+HWPVS K G K P Sbjct: 79 --DIWVTSKLWCN-AHAPEAVPKALEKTLKDLKLDYLDEYLIHWPVSFKTGEDKFP 131
>AK1C4_MACFU (Q95JH4) Aldo-keto reductase family 1 member C4 (EC 1.1.1.-)| (Chlordecone reductase) (EC 1.1.1.225) (CDR) (3-alpha-hydroxysteroid dehydrogenase type I) (EC 1.1.1.50) (3-alpha-HSD1) (Dihydrodiol dehydrogenase 4) (DD4) (DD-4) Length = 323 Score = 81.3 bits (199), Expect = 1e-15 Identities = 48/128 (37%), Positives = 65/128 (50%), Gaps = 3/128 (2%) Frame = +1 Query: 106 MPRIGMGTAVQGPKPDPIRRAV---LRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXXX 276 MP +G G+ P P R V AIE G+RH D+A Y E + Sbjct: 16 MPVLGFGS--YAPPEVPRNRVVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSKIADGS 73 Query: 277 XXXXDDLFITSKLWCSDAHGDRVVPALRHTLRNLQMEYVDLYLVHWPVSMKPGRFKAPFT 456 +D+F TSKLWC+ V PAL +L+ LQ++YVDLYL+H+P+++KPG P Sbjct: 74 VKR-EDIFYTSKLWCTFFRPQLVQPALESSLKKLQLDYVDLYLIHFPMALKPGETPLPKD 132 Query: 457 AEDFVPFD 480 V FD Sbjct: 133 ENGKVMFD 140
>AK1E1_MOUSE (Q9DCT1) Aldo-keto reductase family 1 member E1 (EC 1.1.1.-)| Length = 301 Score = 80.9 bits (198), Expect = 2e-15 Identities = 43/115 (37%), Positives = 59/115 (51%) Frame = +1 Query: 106 MPRIGMGTAVQGPKPDPIRRAVLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXXXXXX 285 +P +G+GT P + AV AI +GYRHFD A Y E+ + Sbjct: 4 IPTVGLGT--WKASPGEVTDAVKLAINLGYRHFDCAYLYHNESEVGMGISEKIKEGVVKR 61 Query: 286 XDDLFITSKLWCSDAHGDRVVPALRHTLRNLQMEYVDLYLVHWPVSMKPGRFKAP 450 +DLF+ SKLWC+ V A +TL L ++Y+DLYL+HWP+ KPG P Sbjct: 62 -EDLFVVSKLWCTCHKKSLVKTACTNTLEALNLDYLDLYLIHWPMGFKPGEKDIP 115
>GCY_YEAST (P14065) GCY protein (EC 1.1.1.-)| Length = 312 Score = 80.5 bits (197), Expect = 2e-15 Identities = 45/117 (38%), Positives = 65/117 (55%) Frame = +1 Query: 94 TVAGMPRIGMGTAVQGPKPDPIRRAVLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXX 273 T A +P+IG+GT K + +AVL A++ GYRH DTAA Y E + Sbjct: 16 TGAQIPQIGLGTWQS--KENDAYKAVLTALKDGYRHIDTAAIYRNEDQVGQAIKDSGVPR 73 Query: 274 XXXXXDDLFITSKLWCSDAHGDRVVPALRHTLRNLQMEYVDLYLVHWPVSMKPGRFK 444 +++F+T+KLWC+ H V AL +L+ L ++YVDLYL+HWP + P K Sbjct: 74 -----EEIFVTTKLWCTQHHEPEV--ALDQSLKRLGLDYVDLYLMHWPARLDPAYIK 123
>ALDR_HUMAN (P15121) Aldose reductase (EC 1.1.1.21) (AR) (Aldehyde reductase)| Length = 315 Score = 80.1 bits (196), Expect = 3e-15 Identities = 46/127 (36%), Positives = 65/127 (51%) Frame = +1 Query: 100 AGMPRIGMGTAVQGPKPDPIRRAVLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXXXX 279 A MP +G+GT P + AV AI++GYRH D A Y+ E + Sbjct: 10 AKMPILGLGTWKS--PPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVV 67 Query: 280 XXXDDLFITSKLWCSDAHGDRVVPALRHTLRNLQMEYVDLYLVHWPVSMKPGRFKAPFTA 459 ++LFI SKLWC+ V A + TL +L+++Y+DLYL+HWP KPG+ Sbjct: 68 KR-EELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK------- 119 Query: 460 EDFVPFD 480 +F P D Sbjct: 120 -EFFPLD 125
>DDBX_BOVIN (P52898) Dihydrodiol dehydrogenase 3 (EC 1.-.-.-) (Prostaglandin F| synthase) Length = 323 Score = 79.3 bits (194), Expect = 5e-15 Identities = 43/116 (37%), Positives = 62/116 (53%), Gaps = 1/116 (0%) Frame = +1 Query: 106 MPRIGMGTAVQGPKPDPIRRAVLR-AIEIGYRHFDTAAHYETEAPIXXXXXXXXXXXXXX 282 +P +G GT P V + AIE G+RH D+A Y+ E + Sbjct: 16 IPVLGFGTFAPREVPKSEALEVTKFAIEAGFRHIDSAHLYQNEEQVGQAIRSKIADGTVK 75 Query: 283 XXDDLFITSKLWCSDAHGDRVVPALRHTLRNLQMEYVDLYLVHWPVSMKPGRFKAP 450 +D+F TSKLW + + V PAL +L NLQ++YVDLY++H+PV++KPG P Sbjct: 76 R-EDIFYTSKLWSTSLRPELVRPALEKSLNNLQLDYVDLYIIHFPVALKPGETLFP 130
>ALDR_RABIT (P15122) Aldose reductase (EC 1.1.1.21) (AR) (Aldehyde reductase)| Length = 315 Score = 78.6 bits (192), Expect = 9e-15 Identities = 46/128 (35%), Positives = 65/128 (50%), Gaps = 1/128 (0%) Frame = +1 Query: 100 AGMPRIGMGTAVQGPKPDPIRRAVLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXXXX 279 A MP +G+GT P + AV AI++GYRH D A Y+ E + Sbjct: 10 AKMPILGLGTWKS--PPGQVTEAVKTAIDLGYRHIDCAHVYQNENEVGVALQEKLKEQVV 67 Query: 280 XXXDDLFITSKLWCSDAHGDRVVPALRHTLRNLQMEYVDLYLVHWPVSMKPGRFKAPF-T 456 ++LFI SKLWC+ V A + TL +L+++Y+DLYL+HWP K G P Sbjct: 68 KR-EELFIVSKLWCTSHDKSLVKGACQKTLNDLKLDYLDLYLIHWPTGFKHGSEYFPLDA 126 Query: 457 AEDFVPFD 480 A + +P D Sbjct: 127 AGNVIPSD 134
>PE2R_RABIT (P80508) Prostaglandin-E(2) 9-reductase (EC 1.1.1.189)| (20-alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.149) (20-alpha-HSD) Length = 323 Score = 78.6 bits (192), Expect = 9e-15 Identities = 40/111 (36%), Positives = 61/111 (54%), Gaps = 1/111 (0%) Frame = +1 Query: 106 MPRIGMGTAVQGPKP-DPIRRAVLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXXXXX 282 +P +G GT P A AI+ G+RH D+A Y+ E + Sbjct: 16 IPVLGFGTYAPEEVPKSKAMEATKIAIDAGFRHIDSAYFYKNEKEVGLAIRSKIADGTVK 75 Query: 283 XXDDLFITSKLWCSDAHGDRVVPALRHTLRNLQMEYVDLYLVHWPVSMKPG 435 +D+F TSKLWC+ + V P+L +L+NLQ++YVDLY++H+P ++KPG Sbjct: 76 R-EDIFYTSKLWCTFHRPELVRPSLEDSLKNLQLDYVDLYIIHFPTALKPG 125
>ALDX_SPOSA (P27800) Aldehyde reductase 1 (EC 1.1.1.2) (Aldehyde reductase I)| (Alcohol dehydrogenase [NADP+]) (ALR) Length = 322 Score = 78.2 bits (191), Expect = 1e-14 Identities = 44/113 (38%), Positives = 59/113 (52%) Frame = +1 Query: 94 TVAGMPRIGMGTAVQGPKPDPIRRAVLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXX 273 T A + +G GT P + + V AIE GYRH D A Y + + Sbjct: 8 TGASLELVGYGTWQAAP--GEVGQGVKVAIETGYRHLDLAKVYSNQPEVGAAIKEAGVKR 65 Query: 274 XXXXXDDLFITSKLWCSDAHGDRVVPALRHTLRNLQMEYVDLYLVHWPVSMKP 432 +DLFITSKLW + ++V PAL TL+ L +EY+DLYL+HWPV+ P Sbjct: 66 -----EDLFITSKLWNNSHRPEQVEPALDDTLKELGLEYLDLYLIHWPVAFPP 113
>AK1C3_PONPY (Q5R7C9) Aldo-keto reductase family 1 member C3 homolog (EC| 1.-.-.-) (Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase) (EC 1.3.1.20) (3-alpha-hydroxysteroid dehydrogenase type 2) (EC 1.1.1.213) (3-alpha-HSD type 2) (Prostaglandin F synthase) Length = 323 Score = 77.8 bits (190), Expect = 1e-14 Identities = 46/127 (36%), Positives = 65/127 (51%), Gaps = 1/127 (0%) Frame = +1 Query: 106 MPRIGMGTAVQGPKPDPIRRAVLR-AIEIGYRHFDTAAHYETEAPIXXXXXXXXXXXXXX 282 MP +G GT P V + AIE G+RH D+A Y E + Sbjct: 16 MPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVK 75 Query: 283 XXDDLFITSKLWCSDAHGDRVVPALRHTLRNLQMEYVDLYLVHWPVSMKPGRFKAPFTAE 462 +D+F TSKLW + + V PAL ++L+ Q++YVDLYL+H P+S+KPG +P Sbjct: 76 R-EDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEELSPTDEN 134 Query: 463 DFVPFDM 483 V FD+ Sbjct: 135 GKVIFDI 141
>AK1C3_HUMAN (P42330) Aldo-keto reductase family 1 member C3 (EC 1.-.-.-)| (Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase) (EC 1.3.1.20) (3-alpha-hydroxysteroid dehydrogenase type 2) (EC 1.1.1.213) (3-alpha-HSD type 2) (3-alpha-HSD type II, brain) (Prost Length = 323 Score = 77.8 bits (190), Expect = 1e-14 Identities = 46/127 (36%), Positives = 65/127 (51%), Gaps = 1/127 (0%) Frame = +1 Query: 106 MPRIGMGTAVQGPKPDPIRRAVLR-AIEIGYRHFDTAAHYETEAPIXXXXXXXXXXXXXX 282 MP +G GT P V + AIE G+RH D+A Y E + Sbjct: 16 MPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVK 75 Query: 283 XXDDLFITSKLWCSDAHGDRVVPALRHTLRNLQMEYVDLYLVHWPVSMKPGRFKAPFTAE 462 +D+F TSKLW + + V PAL ++L+ Q++YVDLYL+H P+S+KPG +P Sbjct: 76 R-EDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEELSPTDEN 134 Query: 463 DFVPFDM 483 V FD+ Sbjct: 135 GKVIFDI 141
>ALD1_MOUSE (P21300) Aldose reductase-related protein 1 (EC 1.1.1.21) (AR)| (Aldehyde reductase) (VAS deferens androgen-dependent protein) (MVDP) (Aldo-keto reductase family 1 member B7) Length = 315 Score = 77.0 bits (188), Expect = 3e-14 Identities = 44/119 (36%), Positives = 60/119 (50%) Frame = +1 Query: 94 TVAGMPRIGMGTAVQGPKPDPIRRAVLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXX 273 T A MP +G+GT P ++ AV AI+ GYRH D A Y E + Sbjct: 8 TKAKMPLVGLGTWKSSP--GQVKEAVKAAIDAGYRHIDCAYVYHNENEVGEAIQEKIKEN 65 Query: 274 XXXXXDDLFITSKLWCSDAHGDRVVPALRHTLRNLQMEYVDLYLVHWPVSMKPGRFKAP 450 +DLFI SKLW + V A ++TL +L+++Y+DLYLVHWP + G P Sbjct: 66 AVKR-EDLFIVSKLWATFFEKSLVKKAFQNTLSDLKLDYLDLYLVHWPQGFQAGNALLP 123
>ALD2_CRIGR (O08782) Aldose reductase-related protein 2 (EC 1.1.1.21) (AR)| (Aldehyde reductase) (Aldo-keto reductase) Length = 315 Score = 76.6 bits (187), Expect = 3e-14 Identities = 44/115 (38%), Positives = 63/115 (54%) Frame = +1 Query: 94 TVAGMPRIGMGTAVQGPKPDPIRRAVLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXX 273 T A MP +G+GT Q P P ++ AV AI+ GYRH D A Y E + Sbjct: 8 TKAKMPIVGLGTW-QSP-PGQVKEAVKVAIDAGYRHIDCAYAYYNEHEVGEAIQEKIKEK 65 Query: 274 XXXXXDDLFITSKLWCSDAHGDRVVPALRHTLRNLQMEYVDLYLVHWPVSMKPGR 438 +DLFI SKLW + + A + TL +L+++Y+DLYL+HWP ++PG+ Sbjct: 66 AVRR-EDLFIVSKLWPTCFERKLLKEAFQKTLTDLKLDYLDLYLIHWPQGLQPGK 119
>DKGA_CORSC (P06632) 2,5-diketo-D-gluconic acid reductase A (EC 1.1.1.274)| (2,5-DKG reductase A) (2,5-DKGR A) (25DKGR-A) (AKR5C) Length = 277 Score = 76.6 bits (187), Expect = 3e-14 Identities = 43/104 (41%), Positives = 55/104 (52%) Frame = +1 Query: 106 MPRIGMGTAVQGPKPDPIRRAVLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXXXXXX 285 +P++G G V P +RAV A+E+GYRH DTAA Y E + Sbjct: 13 IPQLGYG--VFKVPPADTQRAVEEALEVGYRHIDTAAIYGNEEGVGAAIAASGIAR---- 66 Query: 286 XDDLFITSKLWCSDAHGDRVVPALRHTLRNLQMEYVDLYLVHWP 417 DDLFIT+KLW GD A+ +L L ++ VDLYLVHWP Sbjct: 67 -DDLFITTKLWNDRHDGDEPAAAIAESLAKLALDQVDLYLVHWP 109
>DHB5_MOUSE (P70694) Estradiol 17 beta-dehydrogenase 5 (EC 1.1.1.-)| (17-beta-HSD 5) Length = 323 Score = 76.3 bits (186), Expect = 4e-14 Identities = 41/116 (35%), Positives = 62/116 (53%), Gaps = 1/116 (0%) Frame = +1 Query: 106 MPRIGMGT-AVQGPKPDPIRRAVLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXXXXX 282 +P +G GT A Q A AI+ G+RH D+A+ Y+ E + Sbjct: 16 IPILGFGTYAPQEVPKSKATEATKIAIDAGFRHIDSASMYQNEKEVGLAIRSKIADGTVK 75 Query: 283 XXDDLFITSKLWCSDAHGDRVVPALRHTLRNLQMEYVDLYLVHWPVSMKPGRFKAP 450 +D+F TSK+WC+ + V L +L+ LQ++YVDLYL+H+P++MKPG P Sbjct: 76 R-EDIFYTSKVWCTFHRPELVRVCLEQSLKQLQLDYVDLYLIHFPMAMKPGENYLP 130
>CRO_RANCA (P17264) Rho crystallin| Length = 323 Score = 76.3 bits (186), Expect = 4e-14 Identities = 43/116 (37%), Positives = 59/116 (50%), Gaps = 1/116 (0%) Frame = +1 Query: 106 MPRIGMGTAVQGPKPDPI-RRAVLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXXXXX 282 MP +G+GT P + AV AI++GYRH D A E I Sbjct: 16 MPILGLGTYAAPDVPKSLAEEAVKTAIDVGYRHIDCAFITGNEMHIGNGIRSKISDGTVK 75 Query: 283 XXDDLFITSKLWCSDAHGDRVVPALRHTLRNLQMEYVDLYLVHWPVSMKPGRFKAP 450 +D+F T KLWC+ D V L +LR++ M+Y+DL+L+HWPVS+KP P Sbjct: 76 R-EDIFYTGKLWCTYFSPDMVRKGLERSLRDVGMDYLDLFLMHWPVSLKPSGASDP 130
>ALD2_MOUSE (P45377) Aldose reductase-related protein 2 (EC 1.1.1.21) (AR)| (Aldehyde reductase) (Fibroblast growth factor-regulated protein) (FR-1 protein) Length = 315 Score = 75.9 bits (185), Expect = 6e-14 Identities = 42/115 (36%), Positives = 62/115 (53%) Frame = +1 Query: 94 TVAGMPRIGMGTAVQGPKPDPIRRAVLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXX 273 T A MP +G+GT P+ ++ AV AI+ GYRH D A Y E + Sbjct: 8 TKAKMPIVGLGTWKS--PPNQVKEAVKAAIDAGYRHIDCAYAYCNENEVGEAIQEKIKEK 65 Query: 274 XXXXXDDLFITSKLWCSDAHGDRVVPALRHTLRNLQMEYVDLYLVHWPVSMKPGR 438 +DLFI SKLW + + A + TL +L+++Y+DLYL+HWP ++PG+ Sbjct: 66 AVQR-EDLFIVSKLWPTCFEKKLLKEAFQKTLTDLKLDYLDLYLIHWPQGLQPGK 119
>AK1CD_MESAU (P82809) Aldo-keto reductase family 1 member C13 (EC 1.1.1.-)| (Morphine 6-dehydrogenase) (EC 1.1.1.218) Length = 322 Score = 75.9 bits (185), Expect = 6e-14 Identities = 43/112 (38%), Positives = 62/112 (55%), Gaps = 2/112 (1%) Frame = +1 Query: 106 MPRIGMGT--AVQGPKPDPIRRAVLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXXXX 279 +P +G GT ++ PK + A L AI +GYRH DTA Y+ E I Sbjct: 16 IPALGFGTYKPIEVPKSKAMEAANL-AIGVGYRHIDTAYAYQIEEEIGQAIQSNIKAGIV 74 Query: 280 XXXDDLFITSKLWCSDAHGDRVVPALRHTLRNLQMEYVDLYLVHWPVSMKPG 435 +D+FIT+KLWC+ + V P+L LQ+E+VDL+++H+PV MK G Sbjct: 75 KR-EDMFITTKLWCTCFQPELVRPSLEKXXXKLQLEHVDLFIMHYPVPMKAG 125
>DKGA_ECO57 (Q8XBT6) 2,5-diketo-D-gluconic acid reductase A (EC 1.1.1.274)| (2,5-DKG reductase A) (2,5-DKGR A) (25DKGR-A) (AKR5C) Length = 275 Score = 75.5 bits (184), Expect = 7e-14 Identities = 41/105 (39%), Positives = 62/105 (59%) Frame = +1 Query: 106 MPRIGMGTAVQGPKPDPIRRAVLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXXXXXX 285 MP++G+G V + + A+ +A+E+GYR FDTAA Y+ E + Sbjct: 15 MPQLGLG--VWQASNEEVITAIQKALEVGYRSFDTAAAYKNEEGVGKALKNASVNR---- 68 Query: 286 XDDLFITSKLWCSDAHGDRVVPALRHTLRNLQMEYVDLYLVHWPV 420 ++LFIT+KLW D + R AL +L+ LQ++Y+DLYL+HWPV Sbjct: 69 -EELFITTKLWNDDHNRPR--EALLDSLKKLQLDYIDLYLMHWPV 110
>DKGA_YERPE (Q8ZI40) 2,5-diketo-D-gluconic acid reductase A (EC 1.1.1.274)| (2,5-DKG reductase A) (2,5-DKGR A) (25DKGR-A) (AKR5C) Length = 277 Score = 75.5 bits (184), Expect = 7e-14 Identities = 42/104 (40%), Positives = 58/104 (55%) Frame = +1 Query: 106 MPRIGMGTAVQGPKPDPIRRAVLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXXXXXX 285 MP++G+G V AV +A+E+GYR DTAA Y+ E + Sbjct: 15 MPQLGLG--VWQASIQETELAVSKALEVGYRSIDTAAIYKNEEGVGKALKAAAVAR---- 68 Query: 286 XDDLFITSKLWCSDAHGDRVVPALRHTLRNLQMEYVDLYLVHWP 417 D+LFIT+KLW D H + AL +L+ LQ++YVDLYL+HWP Sbjct: 69 -DELFITTKLWNDDQHNPQ--QALETSLQKLQLDYVDLYLIHWP 109
>DIDH_RAT (P23457) 3-alpha-hydroxysteroid dehydrogenase (EC 1.1.1.213)| (3-alpha-HSD) (Hydroxyprostaglandin dehydrogenase) Length = 322 Score = 73.9 bits (180), Expect = 2e-13 Identities = 39/111 (35%), Positives = 63/111 (56%), Gaps = 1/111 (0%) Frame = +1 Query: 106 MPRIGMGTAV-QGPKPDPIRRAVLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXXXXX 282 +P +G GT V + D + +A AI+ G+RHFD+A YE E + Sbjct: 16 IPVLGFGTTVPEKVAKDEVIKATKIAIDNGFRHFDSAYLYEVEEEVGQAIRSKIEDGTVK 75 Query: 283 XXDDLFITSKLWCSDAHGDRVVPALRHTLRNLQMEYVDLYLVHWPVSMKPG 435 +D+F TSKLW + + V L TL++ Q++YVDLY++H+P++++PG Sbjct: 76 R-EDIFYTSKLWSTFHRPELVRTCLEKTLKSTQLDYVDLYIIHFPMALQPG 125
>CRO_RANTE (P02532) Rho crystallin| Length = 323 Score = 73.9 bits (180), Expect = 2e-13 Identities = 42/116 (36%), Positives = 59/116 (50%), Gaps = 1/116 (0%) Frame = +1 Query: 106 MPRIGMGTAVQGPKPDPI-RRAVLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXXXXX 282 MP +G+GT P + AV AI++GYRH D A E I Sbjct: 16 MPILGLGTYASPHVPKSLAEEAVKIAIDVGYRHIDCAFITGNEMHIGNGIRSKISDGTVK 75 Query: 283 XXDDLFITSKLWCSDAHGDRVVPALRHTLRNLQMEYVDLYLVHWPVSMKPGRFKAP 450 +D+F T KLWC+ + V L +LR++ M+Y+DL+L+HWPVS+KP P Sbjct: 76 R-EDIFYTGKLWCTYFSPEMVRKGLERSLRDVGMDYLDLFLMHWPVSLKPSGASDP 130
>AKC1H_RAT (P51652) Aldo-keto reductase family 1 member C18 (EC 1.1.-.-)| (20-alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.149) (20-alpha-HSD) (HSD1) Length = 323 Score = 73.9 bits (180), Expect = 2e-13 Identities = 40/111 (36%), Positives = 61/111 (54%), Gaps = 1/111 (0%) Frame = +1 Query: 106 MPRIGMGT-AVQGPKPDPIRRAVLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXXXXX 282 +P +G GT A + + AI++G+RH D + Y+ E I Sbjct: 16 IPVLGFGTYATEENLRKKSMESTKIAIDVGFRHIDCSHLYQNEEEIGQAIVSKIEDGTVK 75 Query: 283 XXDDLFITSKLWCSDAHGDRVVPALRHTLRNLQMEYVDLYLVHWPVSMKPG 435 +D+F TSKLW + + V P+L ++LR L ++YVDLYL+H+PVS+KPG Sbjct: 76 R-EDIFYTSKLWSTSHRPELVRPSLENSLRKLNLDYVDLYLIHFPVSLKPG 125
>DKGB_YERPE (Q8ZH36) 2,5-diketo-D-gluconic acid reductase B (EC 1.1.1.274)| (2,5-DKG reductase B) (2,5-DKGR B) (25DKGR-B) (AKR5D) Length = 267 Score = 73.2 bits (178), Expect = 4e-13 Identities = 33/84 (39%), Positives = 53/84 (63%) Frame = +1 Query: 166 AVLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXXXXXXXDDLFITSKLWCSDAHGDRV 345 +V +A+ +GYR DTA YE EAP+ D+LFIT+K+W ++ D++ Sbjct: 21 SVSQALTLGYRAIDTAQIYENEAPVGQAIQESGINR-----DELFITTKIWIANLSKDKL 75 Query: 346 VPALRHTLRNLQMEYVDLYLVHWP 417 +P+LR +++ L+ +YVDL L+HWP Sbjct: 76 IPSLRESIQKLKTDYVDLTLIHWP 99
>DKGA_SALTY (Q8ZM06) 2,5-diketo-D-gluconic acid reductase A (EC 1.1.1.274)| (2,5-DKG reductase A) (2,5-DKGR A) (25DKGR-A) (AKR5C) Length = 275 Score = 72.8 bits (177), Expect = 5e-13 Identities = 39/105 (37%), Positives = 60/105 (57%) Frame = +1 Query: 106 MPRIGMGTAVQGPKPDPIRRAVLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXXXXXX 285 MP++G+G V + + A+ +A+E+GYR DTA Y+ E + Sbjct: 15 MPQLGLG--VWKASNEEVIAAIHKALEVGYRSIDTATAYQNEEGVGKALKAASVAR---- 68 Query: 286 XDDLFITSKLWCSDAHGDRVVPALRHTLRNLQMEYVDLYLVHWPV 420 ++LFIT+KLW D R AL+ +L+ LQ++Y+DLYL+HWPV Sbjct: 69 -EELFITTKLWNDDQKRPR--EALQESLKKLQLDYLDLYLMHWPV 110
>DKGA_SALTI (P58744) 2,5-diketo-D-gluconic acid reductase A (EC 1.1.1.274)| (2,5-DKG reductase A) (2,5-DKGR A) (25DKGR-A) (AKR5C) Length = 275 Score = 72.8 bits (177), Expect = 5e-13 Identities = 39/105 (37%), Positives = 60/105 (57%) Frame = +1 Query: 106 MPRIGMGTAVQGPKPDPIRRAVLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXXXXXX 285 MP++G+G V + + A+ +A+E+GYR DTA Y+ E + Sbjct: 15 MPQLGLG--VWKASNEEVIAAIHKALEVGYRSIDTATAYQNEEGVGKALKAASVAR---- 68 Query: 286 XDDLFITSKLWCSDAHGDRVVPALRHTLRNLQMEYVDLYLVHWPV 420 ++LFIT+KLW D R AL+ +L+ LQ++Y+DLYL+HWPV Sbjct: 69 -EELFITTKLWNDDQKRPR--EALQESLKKLQLDYLDLYLMHWPV 110
>ARA1_YEAST (P38115) D-arabinose dehydrogenase [NAD(P)+] heavy chain (EC| 1.1.1.117) Length = 344 Score = 72.8 bits (177), Expect = 5e-13 Identities = 43/105 (40%), Positives = 57/105 (54%) Frame = +1 Query: 106 MPRIGMGTAVQGPKPDPIRRAVLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXXXXXX 285 +P +G+GTA K ++AV AI+ GYRH DTA YETE P Sbjct: 33 IPALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETE-PFVGEAIKELLEDGSIK 91 Query: 286 XDDLFITSKLWCSDAHGDRVVPALRHTLRNLQMEYVDLYLVHWPV 420 +DLFIT+K+W D V +L +L+ L +EYVDL L HWP+ Sbjct: 92 REDLFITTKVW--PVLWDEVDRSLNESLKALGLEYVDLLLQHWPL 134
>DKGA_ECOLI (Q46857) 2,5-diketo-D-gluconic acid reductase A (EC 1.1.1.274)| (2,5-DKG reductase A) (2,5-DKGR A) (25DKGR-A) (AKR5C) Length = 275 Score = 72.4 bits (176), Expect = 6e-13 Identities = 40/105 (38%), Positives = 60/105 (57%) Frame = +1 Query: 106 MPRIGMGTAVQGPKPDPIRRAVLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXXXXXX 285 MP++G+G V + + A+ +A+E+GYR DTAA Y+ E + Sbjct: 15 MPQLGLG--VWQASNEEVITAIQKALEVGYRSIDTAAAYKNEEGVGKALKNASVNR---- 68 Query: 286 XDDLFITSKLWCSDAHGDRVVPALRHTLRNLQMEYVDLYLVHWPV 420 ++LFIT+KLW D R AL +L+ LQ++Y+DLYL+HWPV Sbjct: 69 -EELFITTKLWNDDHKRPR--EALLDSLKKLQLDYIDLYLMHWPV 110
>DKGB_ECOLI (P30863) 2,5-diketo-D-gluconic acid reductase B (EC 1.1.1.274)| (2,5-DKG reductase B) (2,5-DKGR B) (25DKGR-B) (AKR5D) Length = 267 Score = 72.4 bits (176), Expect = 6e-13 Identities = 36/104 (34%), Positives = 60/104 (57%) Frame = +1 Query: 106 MPRIGMGTAVQGPKPDPIRRAVLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXXXXXX 285 +P G+GT K D + +V+ A+E+GYR DTA Y+ EA + Sbjct: 3 IPAFGLGTFRL--KDDVVISSVITALELGYRAIDTAQIYDNEAAVGQAIAESGVPRH--- 57 Query: 286 XDDLFITSKLWCSDAHGDRVVPALRHTLRNLQMEYVDLYLVHWP 417 +L+IT+K+W + D+++P+L+ +L+ L+ +YVDL L+HWP Sbjct: 58 --ELYITTKIWIENLSKDKLIPSLKESLQKLRTDYVDLTLIHWP 99
>AKC1H_MOUSE (Q8K023) Aldo-keto reductase family 1 member C18 (EC 1.1.-.-)| (20-alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.149) (20-alpha-HSD) Length = 323 Score = 72.0 bits (175), Expect = 8e-13 Identities = 42/126 (33%), Positives = 64/126 (50%), Gaps = 1/126 (0%) Frame = +1 Query: 106 MPRIGMGT-AVQGPKPDPIRRAVLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXXXXX 282 +P +G GT A + + AI++G+ H D + Y+ E I Sbjct: 16 IPVLGFGTYATEEHLKKKSMESTKIAIDVGFCHIDCSHLYQNEEEIGQAILSKIEDGTVK 75 Query: 283 XXDDLFITSKLWCSDAHGDRVVPALRHTLRNLQMEYVDLYLVHWPVSMKPGRFKAPFTAE 462 +D+F TSKLW + + V P+L ++LR L ++YVDLYL+H+PVS+KPG P Sbjct: 76 R-EDIFYTSKLWSTSHRPELVRPSLENSLRKLNLDYVDLYLIHFPVSLKPGNELLPKDEH 134 Query: 463 DFVPFD 480 + FD Sbjct: 135 GNLIFD 140
>DKGB_SALTY (Q8ZRM7) 2,5-diketo-D-gluconic acid reductase B (EC 1.1.1.274)| (2,5-DKG reductase B) (2,5-DKGR B) (25DKGR-B) (AKR5D) Length = 267 Score = 71.6 bits (174), Expect = 1e-12 Identities = 36/104 (34%), Positives = 60/104 (57%) Frame = +1 Query: 106 MPRIGMGTAVQGPKPDPIRRAVLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXXXXXX 285 +P G+GT K D + +V A+E+GYR DTA Y+ EA + Sbjct: 3 IPAFGLGTFRL--KDDVVIASVKTALELGYRAVDTAQIYDNEAAVGQAIAESGVPR---- 56 Query: 286 XDDLFITSKLWCSDAHGDRVVPALRHTLRNLQMEYVDLYLVHWP 417 ++L+IT+K+W + D+++P+L+ +L+ L+ +YVDL L+HWP Sbjct: 57 -NELYITTKIWIENLSKDKLIPSLKESLKKLRTDYVDLTLIHWP 99
>DKGB_SALTI (Q8Z988) 2,5-diketo-D-gluconic acid reductase B (EC 1.1.1.274)| (2,5-DKG reductase B) (2,5-DKGR B) (25DKGR-B) (AKR5D) Length = 267 Score = 71.6 bits (174), Expect = 1e-12 Identities = 36/104 (34%), Positives = 60/104 (57%) Frame = +1 Query: 106 MPRIGMGTAVQGPKPDPIRRAVLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXXXXXX 285 +P G+GT K D + +V A+E+GYR DTA Y+ EA + Sbjct: 3 IPAFGLGTFRL--KDDVVIASVKTALELGYRAVDTAQIYDNEAAVGQAIAESGVPR---- 56 Query: 286 XDDLFITSKLWCSDAHGDRVVPALRHTLRNLQMEYVDLYLVHWP 417 ++L+IT+K+W + D+++P+L+ +L+ L+ +YVDL L+HWP Sbjct: 57 -NELYITTKIWIENLSKDKLIPSLKESLKKLRTDYVDLTLIHWP 99
>XYL1_PICST (P31867) NAD(P)H-dependent D-xylose reductase (EC 1.1.1.-) (XR)| Length = 318 Score = 71.6 bits (174), Expect = 1e-12 Identities = 42/108 (38%), Positives = 56/108 (51%) Frame = +1 Query: 106 MPRIGMGTAVQGPKPDPIRRAVLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXXXXXX 285 MP +G G D + RAI+ GYR FD A Y E + Sbjct: 12 MPAVGFGC--WKVDVDTCSEQIYRAIKTGYRLFDGAEDYANEK-LVGAGVKKAIDEGIVK 68 Query: 286 XDDLFITSKLWCSDAHGDRVVPALRHTLRNLQMEYVDLYLVHWPVSMK 429 +DLF+TSKLW + H D V AL TL +LQ++YVDL+L+H+PV+ K Sbjct: 69 REDLFLTSKLWNNYHHPDNVEKALNRTLSDLQVDYVDLFLIHFPVTFK 116
>AK1D1_RAT (P31210) 3-oxo-5-beta-steroid 4-dehydrogenase (EC 1.3.99.6)| (Delta(4)-3-ketosteroid 5-beta-reductase) (Aldo-keto reductase family 1 member D1) Length = 326 Score = 71.6 bits (174), Expect = 1e-12 Identities = 44/127 (34%), Positives = 65/127 (51%), Gaps = 2/127 (1%) Frame = +1 Query: 106 MPRIGMGTAVQGPKPDPIRR--AVLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXXXX 279 +P IG+GT P+P P + AV AI+ GYRH D A Y E + Sbjct: 18 IPIIGLGT-YSDPRPVPGKTFIAVKTAIDEGYRHIDGAYVYRNEHEVGEAIREKVAEGKV 76 Query: 280 XXXDDLFITSKLWCSDAHGDRVVPALRHTLRNLQMEYVDLYLVHWPVSMKPGRFKAPFTA 459 +++F KLW +D + V PAL TL+ L+++Y+DLY++ P++ KPG Sbjct: 77 KR-EEIFYCGKLWSTDHDPEMVRPALERTLQTLKLDYIDLYIIEMPMAFKPG-------- 127 Query: 460 EDFVPFD 480 E+F P D Sbjct: 128 EEFYPKD 134
>DKGB_ECO57 (Q8X7Z7) 2,5-diketo-D-gluconic acid reductase B (EC 1.1.1.274)| (2,5-DKG reductase B) (2,5-DKGR B) (25DKGR-B) (AKR5D) Length = 267 Score = 70.9 bits (172), Expect = 2e-12 Identities = 36/104 (34%), Positives = 59/104 (56%) Frame = +1 Query: 106 MPRIGMGTAVQGPKPDPIRRAVLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXXXXXX 285 +P G+GT K D + +V A+E+GYR DTA Y+ EA + Sbjct: 3 IPAFGLGTFRL--KDDVVISSVKTALELGYRAIDTAQIYDNEAAVGLAIAESGVPRH--- 57 Query: 286 XDDLFITSKLWCSDAHGDRVVPALRHTLRNLQMEYVDLYLVHWP 417 +L+IT+K+W + D+++P+L+ +L+ L+ +YVDL L+HWP Sbjct: 58 --ELYITTKIWIENLSKDKLIPSLKESLQKLRTDYVDLTLIHWP 99
>AK1BA_HUMAN (O60218) Aldo-keto reductase family 1 member B10 (EC 1.1.1.-)| (Aldose reductase-like) (ARL-1) (Small intestine reductase) (SI reductase) (Aldose reductase-related protein) (ARP) (hARP) Length = 316 Score = 69.3 bits (168), Expect = 5e-12 Identities = 42/114 (36%), Positives = 59/114 (51%) Frame = +1 Query: 94 TVAGMPRIGMGTAVQGPKPDPIRRAVLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXX 273 T A MP +G+GT + P ++ AV AI+ GYRH D A Y+ E + Sbjct: 9 TKAKMPIVGLGTW-KSPL-GKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEK 66 Query: 274 XXXXXDDLFITSKLWCSDAHGDRVVPALRHTLRNLQMEYVDLYLVHWPVSMKPG 435 +DLFI SKLW + V A TL++L++ Y+D+YL+HWP K G Sbjct: 67 AVKR-EDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSG 119
>AK1D1_MOUSE (Q8VCX1) 3-oxo-5-beta-steroid 4-dehydrogenase (EC 1.3.99.6)| (Delta(4)-3-ketosteroid 5-beta-reductase) (Aldo-keto reductase family 1 member D1) Length = 325 Score = 68.6 bits (166), Expect = 9e-12 Identities = 39/113 (34%), Positives = 61/113 (53%), Gaps = 2/113 (1%) Frame = +1 Query: 106 MPRIGMGTAVQGPKPDPIRR--AVLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXXXX 279 +P IG+GT P+P P + AV AI+ GYRH D A Y E + Sbjct: 18 IPLIGLGT-YSDPRPVPGKTYVAVKTAIDEGYRHIDGAYVYHNEHEVGEAIREKIAEGKV 76 Query: 280 XXXDDLFITSKLWCSDAHGDRVVPALRHTLRNLQMEYVDLYLVHWPVSMKPGR 438 +++F KLW ++ V+PAL TL+ L+++Y+DLY++ P++ KPG+ Sbjct: 77 KR-EEIFYCGKLWNTEHVPSMVLPALERTLKALKLDYIDLYIIELPMAFKPGK 128
>AK1D1_HUMAN (P51857) 3-oxo-5-beta-steroid 4-dehydrogenase (EC 1.3.1.3)| (Delta(4)-3-ketosteroid 5-beta-reductase) (Aldo-keto reductase family 1 member D1) Length = 326 Score = 67.8 bits (164), Expect = 2e-11 Identities = 41/113 (36%), Positives = 59/113 (52%), Gaps = 3/113 (2%) Frame = +1 Query: 106 MPRIGMGTAVQGPKPDP---IRRAVLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXXX 276 +P IG+GT + PK P +V AI+ GYRH D A Y+ E + Sbjct: 18 IPIIGLGTYSE-PKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIREKIAEGK 76 Query: 277 XXXXDDLFITSKLWCSDAHGDRVVPALRHTLRNLQMEYVDLYLVHWPVSMKPG 435 +D+F KLW ++ + V P L TLR LQ++YVDLY++ P++ KPG Sbjct: 77 VRR-EDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPG 128
>XYL1_KLULA (P49378) NAD(P)H-dependent D-xylose reductase (EC 1.1.1.-) (XR)| Length = 329 Score = 67.4 bits (163), Expect = 2e-11 Identities = 40/112 (35%), Positives = 56/112 (50%) Frame = +1 Query: 106 MPRIGMGTAVQGPKPDPIRRAVLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXXXXXX 285 MP +G+G D + AI+IGYR FD A Y E + Sbjct: 16 MPLVGLGCWKM--PNDVCADQIYEAIKIGYRLFDGAQDYANEKEVGQGVNRAIKEGLVKR 73 Query: 286 XDDLFITSKLWCSDAHGDRVVPALRHTLRNLQMEYVDLYLVHWPVSMKPGRF 441 +DL + SKLW S H D V AL TL +LQ++YVD++ +H+P++ KP F Sbjct: 74 -EDLVVVSKLWNSFHHPDNVPRALERTLSDLQLDYVDIFYIHFPLAFKPVPF 124
>P100_LEIMA (P22045) Probable reductase (EC 1.1.-.-)| Length = 284 Score = 67.4 bits (163), Expect = 2e-11 Identities = 36/104 (34%), Positives = 55/104 (52%) Frame = +1 Query: 106 MPRIGMGTAVQGPKPDPIRRAVLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXXXXXX 285 MP+ G+G Q P + AV A+ GYRH DTAA Y+ E + Sbjct: 17 MPQFGLGVW-QSPAGEVTENAVNWALCAGYRHIDTAAIYKNEESVGAGLRASGVPR---- 71 Query: 286 XDDLFITSKLWCSDAHGDRVVPALRHTLRNLQMEYVDLYLVHWP 417 +D+FIT+KLW ++ + + A + + L ++Y+DLYL+HWP Sbjct: 72 -EDVFITTKLWNTEQGYESTLAAFEESRQKLGVDYIDLYLIHWP 114
>AK1D1_RABIT (Q9TV64) 3-oxo-5-beta-steroid 4-dehydrogenase (EC 1.3.99.6)| (Delta(4)-3-ketosteroid 5-beta-reductase) (Aldo-keto reductase family 1 member D1) Length = 326 Score = 65.5 bits (158), Expect = 8e-11 Identities = 41/124 (33%), Positives = 63/124 (50%), Gaps = 3/124 (2%) Frame = +1 Query: 73 PMGAGDRTVAGMPRIGMGTAVQGPKPDP---IRRAVLRAIEIGYRHFDTAAHYETEAPIX 243 P+G G+ +P IG+GT + PK P +V AI+ GYRH D A Y+ E + Sbjct: 11 PLGDGN----SIPIIGLGTYSE-PKTTPKGSCATSVKIAIDTGYRHIDGAYIYQNEHEVG 65 Query: 244 XXXXXXXXXXXXXXXDDLFITSKLWCSDAHGDRVVPALRHTLRNLQMEYVDLYLVHWPVS 423 +D+F KLW ++ V P L TL+ L+++Y+DLY++ P++ Sbjct: 66 ETFREKIAEGKVRR-EDIFYCGKLWATNHDPVMVRPTLERTLKVLKLDYIDLYIIEIPMA 124 Query: 424 MKPG 435 KPG Sbjct: 125 FKPG 128
>YPR1_YEAST (Q12458) Putative reductase 1 (EC 1.1.1.-)| Length = 312 Score = 63.5 bits (153), Expect = 3e-10 Identities = 39/115 (33%), Positives = 58/115 (50%) Frame = +1 Query: 94 TVAGMPRIGMGTAVQGPKPDPIRRAVLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXX 273 T A +P +G GT +V+ A++ GYRH D AA Y E + Sbjct: 16 TGASIPVLGFGTWRSVDNNG--YHSVIAALKAGYRHIDAAAIYLNEEEVGRAIKDSGVPR 73 Query: 274 XXXXXDDLFITSKLWCSDAHGDRVVPALRHTLRNLQMEYVDLYLVHWPVSMKPGR 438 +++FIT+KLW ++ AL +L+ L ++YVDLYL+HWPV +K R Sbjct: 74 -----EEIFITTKLWGTEQRDPEA--ALNKSLKRLGLDYVDLYLMHWPVPLKTDR 121
>XYL1_ASPNG (Q9P8R5) NAD(P)H-dependent D-xylose reductase (EC 1.1.1.-) (XR)| Length = 319 Score = 62.8 bits (151), Expect = 5e-10 Identities = 39/108 (36%), Positives = 52/108 (48%) Frame = +1 Query: 106 MPRIGMGTAVQGPKPDPIRRAVLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXXXXXX 285 MP +G G + D + AI+ GYR FD A Y E Sbjct: 14 MPLVGFG--LWKVNNDTCADQIYHAIKEGYRLFDGACDYGNEVE-AGQGIARAIKDGLVK 70 Query: 286 XDDLFITSKLWCSDAHGDRVVPALRHTLRNLQMEYVDLYLVHWPVSMK 429 ++LFI SKLW S GDRV P R L + ++Y DLY+VH+P+S+K Sbjct: 71 REELFIVSKLWNSFHDGDRVEPICRKQLADWGIDYFDLYIVHFPISLK 118
>GRE3_YEAST (P38715) NADPH-dependent aldose reductase GRE3 (EC 1.1.1.21)| (NADPH-dependent aldo-keto reductase GRE3) (NADPH-dependent methylglyoxal reductase GRE3) (EC 1.1.1.-) (Xylose reductase) (EC 1.1.1.-) (Genes de respuesta a estres protein 3) Length = 327 Score = 62.0 bits (149), Expect = 8e-10 Identities = 35/108 (32%), Positives = 54/108 (50%) Frame = +1 Query: 106 MPRIGMGTAVQGPKPDPIRRAVLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXXXXXX 285 MP +G+G K + AI++GYR FD A Y E + Sbjct: 13 MPLVGLGCWKIDKKV--CANQIYEAIKLGYRLFDGACDYGNEKEVGEGIRKAISEGLVSR 70 Query: 286 XDDLFITSKLWCSDAHGDRVVPALRHTLRNLQMEYVDLYLVHWPVSMK 429 D +F+ SKLW + H D V AL+ TL ++ ++Y+DLY +H+P++ K Sbjct: 71 KD-IFVVSKLWNNFHHPDHVKLALKKTLSDMGLDYLDLYYIHFPIAFK 117
>XYL1_CANPA (Q6Y0Z3) NADH-dependent D-xylose reductase (EC 1.1.1.175) (XR)| Length = 324 Score = 61.2 bits (147), Expect = 1e-09 Identities = 34/88 (38%), Positives = 47/88 (53%) Frame = +1 Query: 169 VLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXXXXXXXDDLFITSKLWCSDAHGDRVV 348 + RAI+ GYR FD A Y E + ++LFITSKLW S V Sbjct: 37 IYRAIKSGYRLFDGAEDYANEQEVGEGIKRAIKEGIVKR-EELFITSKLWNSFHDKKNVE 95 Query: 349 PALRHTLRNLQMEYVDLYLVHWPVSMKP 432 AL TL +L ++YVDL+ +H+P++ KP Sbjct: 96 VALMKTLSDLNLDYVDLFYIHFPIAQKP 123
>XYL1_PICGU (O94735) NADPH-dependent D-xylose reductase (EC 1.1.1.-) (XR)| Length = 317 Score = 59.3 bits (142), Expect = 5e-09 Identities = 35/104 (33%), Positives = 52/104 (50%) Frame = +1 Query: 169 VLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXXXXXXXDDLFITSKLWCSDAHGDRVV 348 + AI++GYR FD A Y E + D+LF+ SKLW S V Sbjct: 30 IYNAIKVGYRLFDGAEDYGNEKEVGDGINRALDEGLVAR-DELFVVSKLWNSFHDPKNVE 88 Query: 349 PALRHTLRNLQMEYVDLYLVHWPVSMKPGRFKAPFTAEDFVPFD 480 AL TL +L+++Y+DL+L+H+P++ K FVPF+ Sbjct: 89 KALDKTLSDLKVDYLDLFLIHFPIAFK------------FVPFE 120
>MORA_PSEPU (Q02198) Morphine 6-dehydrogenase (EC 1.1.1.218) (Naloxone| reductase) Length = 295 Score = 59.3 bits (142), Expect = 5e-09 Identities = 35/104 (33%), Positives = 51/104 (49%) Frame = +1 Query: 106 MPRIGMGTAVQGPKPDPIRRAVLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXXXXXX 285 MP +G+G V + A+ AI GYR DTA Y EA + Sbjct: 15 MPALGLG--VFAASAEETASAIASAISSGYRLIDTARSYNNEAQVGEGIRNSGVDRA--- 69 Query: 286 XDDLFITSKLWCSDAHGDRVVPALRHTLRNLQMEYVDLYLVHWP 417 ++F+T+KL+ D +R + A +L L ++YVDLYL+HWP Sbjct: 70 --EMFVTTKLFNCDYGYERALRAFDESLGRLGLDYVDLYLLHWP 111
>XYL1_CANSH (Q9P430) NAD(P)H-dependent D-xylose reductase (EC 1.1.1.-) (XR)| Length = 323 Score = 59.3 bits (142), Expect = 5e-09 Identities = 39/110 (35%), Positives = 56/110 (50%), Gaps = 2/110 (1%) Frame = +1 Query: 106 MPRIGMGTAVQGPKPDPIRRA--VLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXXXX 279 MP IG G K D A V AI+ GYR FD A Y E + Sbjct: 17 MPSIGFGCW----KLDKSTAADQVYNAIKAGYRLFDGAEDYGNEQEVGEGVKRAIDEGIV 72 Query: 280 XXXDDLFITSKLWCSDAHGDRVVPALRHTLRNLQMEYVDLYLVHWPVSMK 429 +++F+TSKLW + V AL TL++L+++YVDL+L+H+P++ K Sbjct: 73 TR-EEIFLTSKLWNNYHDPKNVETALNKTLKDLKVDYVDLFLIHFPIAFK 121
>XYL1_PACTA (P78736) NAD(P)H-dependent D-xylose reductase (EC 1.1.1.-) (XR)| Length = 318 Score = 58.9 bits (141), Expect = 7e-09 Identities = 43/125 (34%), Positives = 57/125 (45%) Frame = +1 Query: 106 MPRIGMGTAVQGPKPDPIRRAVLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXXXXXX 285 +P IGMG K + V AI+ GYR FD A Y E + Sbjct: 14 IPAIGMGCW----KLENAADMVYAAIKEGYRLFDCACDYGNEKEVGEGINRAIKDGLVKR 69 Query: 286 XDDLFITSKLWCSDAHGDRVVPALRHTLRNLQMEYVDLYLVHWPVSMKPGRFKAPFTAED 465 D LFITSKLW + + V AL +L + ++Y DLYL+H+P+S K Sbjct: 70 KD-LFITSKLWNNFHAKENVKKALMKSLSDFNLDYFDLYLMHFPISFK------------ 116 Query: 466 FVPFD 480 FVPF+ Sbjct: 117 FVPFE 121
>XYL1_CANTE (O74237) NAD(P)H-dependent D-xylose reductase (EC 1.1.1.-) (XR)| Length = 322 Score = 58.2 bits (139), Expect = 1e-08 Identities = 38/113 (33%), Positives = 56/113 (49%), Gaps = 5/113 (4%) Frame = +1 Query: 106 MPRIGMG-----TAVQGPKPDPIRRAVLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXX 270 MP IG G A G + V +AI+ GYR FD A Y E + Sbjct: 16 MPSIGFGCWKLANATAGEQ-------VYQAIKAGYRLFDGAEDYGNEKEVGDGVKRAIDE 68 Query: 271 XXXXXXDDLFITSKLWCSDAHGDRVVPALRHTLRNLQMEYVDLYLVHWPVSMK 429 +++F+TSKLW + V AL TL +L+++YVDL+L+H+P++ K Sbjct: 69 GLVKR-EEIFLTSKLWNNYHDPKNVETALNKTLADLKVDYVDLFLIHFPIAFK 120
>XYL2_CANTR (P87039) NADPH-dependent D-xylose reductase II,III (EC 1.1.1.-)| (XR) Length = 324 Score = 58.2 bits (139), Expect = 1e-08 Identities = 32/87 (36%), Positives = 46/87 (52%) Frame = +1 Query: 169 VLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXXXXXXXDDLFITSKLWCSDAHGDRVV 348 + AI+ GYR FD A Y E + ++LFITSKLW + V Sbjct: 37 IYNAIKTGYRLFDGAEDYGNEKEVGEGINRAIKEGLVKR-EELFITSKLWNNFHDPKNVE 95 Query: 349 PALRHTLRNLQMEYVDLYLVHWPVSMK 429 AL TL +L ++YVDL+L+H+P++ K Sbjct: 96 TALNKTLSDLNLDYVDLFLIHFPIAFK 122
>XYL1_CANTR (O13283) NAD(P)H-dependent D-xylose reductase I,II (EC 1.1.1.-)| (XR) Length = 324 Score = 58.2 bits (139), Expect = 1e-08 Identities = 32/87 (36%), Positives = 46/87 (52%) Frame = +1 Query: 169 VLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXXXXXXXDDLFITSKLWCSDAHGDRVV 348 + AI+ GYR FD A Y E + ++LFITSKLW + V Sbjct: 37 IYNAIKTGYRLFDGAEDYGNEKEVGEGINRAIKEGLVKR-EELFITSKLWNNFHDPKNVE 95 Query: 349 PALRHTLRNLQMEYVDLYLVHWPVSMK 429 AL TL +L ++YVDL+L+H+P++ K Sbjct: 96 TALNKTLSDLNLDYVDLFLIHFPIAFK 122
>XYL1_TRIRE (Q876L8) NAD(P)H-dependent D-xylose reductase (EC 1.1.1.-) (XR)| Length = 324 Score = 55.8 bits (133), Expect = 6e-08 Identities = 32/87 (36%), Positives = 44/87 (50%) Frame = +1 Query: 169 VLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXXXXXXXDDLFITSKLWCSDAHGDRVV 348 V AI+ GYR FD A Y E +DLFI SKLW + D+V Sbjct: 33 VYNAIKAGYRLFDGACDYGNEKECGEGVARAIKDGLVKR-EDLFIVSKLWQTFHDEDKVE 91 Query: 349 PALRHTLRNLQMEYVDLYLVHWPVSMK 429 P R L + Q++Y DL+LVH+P +++ Sbjct: 92 PITRRQLADWQIDYFDLFLVHFPAALE 118
>YOF5_CAEEL (Q09632) Probable oxidoreductase ZK1290.5 in chromosome II (EC| 1.-.-.-) Length = 321 Score = 52.8 bits (125), Expect = 5e-07 Identities = 35/105 (33%), Positives = 52/105 (49%), Gaps = 1/105 (0%) Frame = +1 Query: 106 MPRIGMGTAVQGPKPDPIRRAVLRAIE-IGYRHFDTAAHYETEAPIXXXXXXXXXXXXXX 282 MP IG+GT G AVL +I+ GYR DTA Y E + Sbjct: 13 MPLIGLGTTHSGGY---YHDAVLHSIKKCGYRLIDTAKRYGVEKQLGIAVKNCSVPR--- 66 Query: 283 XXDDLFITSKLWCSDAHGDRVVPALRHTLRNLQMEYVDLYLVHWP 417 +++F+++KLW D GD V A + + LQ +Y+D+Y++H P Sbjct: 67 --EEMFLSTKLWPVDC-GDEVYNAFQTSCEKLQTDYLDMYMIHMP 108
>DTDH_MUCMU (Q01213) 4-dihydromethyl-trisporate dehydrogenase (EC 1.1.1.-)| (4-dihydromethyl-TA dehydrogenase) Length = 321 Score = 50.8 bits (120), Expect = 2e-06 Identities = 39/115 (33%), Positives = 54/115 (46%), Gaps = 1/115 (0%) Frame = +1 Query: 88 DRTVAGMPRIGMGTAVQGPKPDPIRRAVLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXX 267 +RT MP G G K V +AI+ GYR FD A Y E + Sbjct: 9 NRTGDKMPIRGFGCWKIDTKD--CEETVYQAIKTGYRLFDGACDYGNEVEVGRGINKAIN 66 Query: 268 XXXXXXXDDLFITSKLWCSDAHGDRVVPAL-RHTLRNLQMEYVDLYLVHWPVSMK 429 +DLFI +KLW + H + V AL L++ +EY DLYL+H+PV ++ Sbjct: 67 EGLVKR-EDLFIVTKLW-NTFHSKKHVRALFDRQLKDTGLEYFDLYLIHFPVPLQ 119
>DKGB_CORSS (P15339) 2,5-diketo-D-gluconic acid reductase B (EC 1.1.1.274)| (2,5-DKG reductase B) (2,5-DKGR B) (25DKGR-B) (AKR5D) Length = 276 Score = 48.9 bits (115), Expect = 7e-06 Identities = 30/105 (28%), Positives = 47/105 (44%) Frame = +1 Query: 103 GMPRIGMGTAVQGPKPDPIRRAVLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXXXXX 282 G P G + D A++ AI+ GYR DTA +YE E+ + Sbjct: 11 GRPFAEPGLGTYNLRGDEGVAAMVAAIDSGYRLLDTAVNYENESEV-----GRAVRASSV 65 Query: 283 XXDDLFITSKLWCSDAHGDRVVPALRHTLRNLQMEYVDLYLVHWP 417 D+L + SK+ V ++R +L L ++ +DL L+HWP Sbjct: 66 DRDELIVASKIPGRQHGRAEAVDSIRGSLDRLGLDVIDLQLIHWP 110
>YEAE_ECOLI (P76234) Hypothetical protein yeaE| Length = 284 Score = 47.0 bits (110), Expect = 3e-05 Identities = 32/106 (30%), Positives = 48/106 (45%), Gaps = 3/106 (2%) Frame = +1 Query: 106 MPRIGMGTAVQGPKPDPIRR--AVLRA-IEIGYRHFDTAAHYETEAPIXXXXXXXXXXXX 276 +P +G GT G + A LRA IE+G DTA Y Sbjct: 14 LPAVGQGTWYMGEDASQRKTEVAALRAGIELGLTLIDTAEMYADGG-----AEKVVGEAL 68 Query: 277 XXXXDDLFITSKLWCSDAHGDRVVPALRHTLRNLQMEYVDLYLVHW 414 + +F+ SK++ +A G + + A +LR L +Y+DLYL+HW Sbjct: 69 TGLREKVFLVSKVYPWNAGGQKAINACEASLRRLNTDYLDLYLLHW 114
>YJ66_YEAST (P47137) Probable oxidoreductase YJR096W (EC 1.-.-.-)| Length = 282 Score = 47.0 bits (110), Expect = 3e-05 Identities = 27/86 (31%), Positives = 41/86 (47%), Gaps = 2/86 (2%) Frame = +1 Query: 169 VLRAIEIGYRHFDTAAHYETEAPIXXXXXX-XXXXXXXXXXDDLFITSKLWCSDAHGDRV 345 V ++ GYRHFDTA Y E + +++F T+KLW S R Sbjct: 33 VYEGVKCGYRHFDTAVLYGNEKEVGDGIIKWLNEDPGNHKREEIFYTTKLWNSQNGYKRA 92 Query: 346 VPALRHTLRNLQ-MEYVDLYLVHWPV 420 A+R L + ++Y+DL L+H P+ Sbjct: 93 KAAIRQCLNEVSGLQYIDLLLIHSPL 118
>AFR_PIG (P82125) 1,5-anhydro-D-fructose reductase (EC 1.1.1.263) (AF| reductase) (Fragments) Length = 206 Score = 44.7 bits (104), Expect = 1e-04 Identities = 33/115 (28%), Positives = 46/115 (40%) Frame = +1 Query: 106 MPRIGMGTAVQGPKPDPIRRAVLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXXXXXX 285 +P +G+GT P + + AV AI+ GYRH D+A Y E + Sbjct: 2 IPVLGLGTWQAAPGGE-VTEAVKVAIDTGYRHPDSAYLYHNEDEVGVGIQAKIDEGVVRR 60 Query: 286 XDDLFITSKLWCSDAHGDRVVPALRHTLRNLQMEYVDLYLVHWPVSMKPGRFKAP 450 +DLFI SK + Y+DL +HWP+ KPG P Sbjct: 61 -EDLFIVSK----------------------KXXYLDLXNIHWPMQFKPGEVDLP 92
>GS69_BACSU (P80874) General stress protein 69 (EC 1.1.1.-) (GSP69) (AKR11B)| Length = 331 Score = 38.9 bits (89), Expect = 0.008 Identities = 19/55 (34%), Positives = 31/55 (56%) Frame = +1 Query: 328 AHGDRVVPALRHTLRNLQMEYVDLYLVHWPVSMKPGRFKAPFTAEDFVPFDMRAV 492 A+ R+V + ++L+ LQ +Y+DLY VHWP + P A E + +RA+ Sbjct: 98 ANRARIVEEVENSLKRLQTDYIDLYQVHWPDPLVPIEETAEVMKELYDAGKIRAI 152
>TAS_SHIFL (P0A9T5) Protein tas| Length = 346 Score = 34.3 bits (77), Expect = 0.19 Identities = 13/22 (59%), Positives = 17/22 (77%) Frame = +1 Query: 352 ALRHTLRNLQMEYVDLYLVHWP 417 AL +L+ LQ +Y+DLY VHWP Sbjct: 113 ALHDSLKRLQTDYLDLYQVHWP 134
>TAS_ECOLI (P0A9T4) Protein tas| Length = 346 Score = 34.3 bits (77), Expect = 0.19 Identities = 13/22 (59%), Positives = 17/22 (77%) Frame = +1 Query: 352 ALRHTLRNLQMEYVDLYLVHWP 417 AL +L+ LQ +Y+DLY VHWP Sbjct: 113 ALHDSLKRLQTDYLDLYQVHWP 134
>KCAB1_RAT (P63144) Voltage-gated potassium channel beta-1 subunit (K(+)| channel beta-1 subunit) (Kv-beta-1) Length = 401 Score = 33.5 bits (75), Expect = 0.32 Identities = 35/116 (30%), Positives = 49/116 (42%), Gaps = 10/116 (8%) Frame = +1 Query: 115 IGMGTAVQ--GPKPDPI-RRAVLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXXXXXX 285 +G+GT V G D + R + A E G FDTA Y A Sbjct: 86 LGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYA--AGKAEVILGSIIKKKGWR 143 Query: 286 XDDLFITSKL-WCSDAHGDR------VVPALRHTLRNLQMEYVDLYLVHWPVSMKP 432 L IT+KL W A +R ++ L+ +L+ LQ+EYVD+ + P S P Sbjct: 144 RSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPDSNTP 199
>KCAB1_RABIT (Q9XT31) Voltage-gated potassium channel beta-1 subunit (K(+)| channel beta-1 subunit) (Kv-beta-1) Length = 419 Score = 33.5 bits (75), Expect = 0.32 Identities = 35/116 (30%), Positives = 49/116 (42%), Gaps = 10/116 (8%) Frame = +1 Query: 115 IGMGTAVQ--GPKPDPI-RRAVLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXXXXXX 285 +G+GT V G D + R + A E G FDTA Y A Sbjct: 104 LGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYA--AGKAEVILGSIIKKKGWR 161 Query: 286 XDDLFITSKL-WCSDAHGDR------VVPALRHTLRNLQMEYVDLYLVHWPVSMKP 432 L IT+KL W A +R ++ L+ +L+ LQ+EYVD+ + P S P Sbjct: 162 RSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPDSNTP 217
>KCAB1_MUSPU (Q28528) Voltage-gated potassium channel beta-1 subunit (K(+)| channel beta-1 subunit) (Kv-beta-1) Length = 408 Score = 33.5 bits (75), Expect = 0.32 Identities = 35/116 (30%), Positives = 49/116 (42%), Gaps = 10/116 (8%) Frame = +1 Query: 115 IGMGTAVQ--GPKPDPI-RRAVLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXXXXXX 285 +G+GT V G D + R + A E G FDTA Y A Sbjct: 93 LGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYA--AGKAEVILGSIIKKKGWR 150 Query: 286 XDDLFITSKL-WCSDAHGDR------VVPALRHTLRNLQMEYVDLYLVHWPVSMKP 432 L IT+KL W A +R ++ L+ +L+ LQ+EYVD+ + P S P Sbjct: 151 RSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPDSNTP 206
>KCAB1_MOUSE (P63143) Voltage-gated potassium channel beta-1 subunit (K(+)| channel beta-1 subunit) (Kv-beta-1) Length = 401 Score = 33.5 bits (75), Expect = 0.32 Identities = 35/116 (30%), Positives = 49/116 (42%), Gaps = 10/116 (8%) Frame = +1 Query: 115 IGMGTAVQ--GPKPDPI-RRAVLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXXXXXX 285 +G+GT V G D + R + A E G FDTA Y A Sbjct: 86 LGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYA--AGKAEVILGSIIKKKGWR 143 Query: 286 XDDLFITSKL-WCSDAHGDR------VVPALRHTLRNLQMEYVDLYLVHWPVSMKP 432 L IT+KL W A +R ++ L+ +L+ LQ+EYVD+ + P S P Sbjct: 144 RSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPDSNTP 199
>KCAB1_HUMAN (Q14722) Voltage-gated potassium channel beta-1 subunit (K(+)| channel beta-1 subunit) (Kv-beta-1) Length = 419 Score = 33.5 bits (75), Expect = 0.32 Identities = 35/116 (30%), Positives = 49/116 (42%), Gaps = 10/116 (8%) Frame = +1 Query: 115 IGMGTAVQ--GPKPDPI-RRAVLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXXXXXX 285 +G+GT V G D + R + A E G FDTA Y A Sbjct: 104 LGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYA--AGKAEVILGSIIKKKGWR 161 Query: 286 XDDLFITSKL-WCSDAHGDR------VVPALRHTLRNLQMEYVDLYLVHWPVSMKP 432 L IT+KL W A +R ++ L+ +L+ LQ+EYVD+ + P S P Sbjct: 162 RSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPDSNTP 217
>KCAB1_BOVIN (Q4PJK1) Voltage-gated potassium channel beta-1 subunit (K(+)| channel beta-1 subunit) (Kv-beta-1) Length = 401 Score = 33.5 bits (75), Expect = 0.32 Identities = 35/116 (30%), Positives = 49/116 (42%), Gaps = 10/116 (8%) Frame = +1 Query: 115 IGMGTAVQ--GPKPDPI-RRAVLRAIEIGYRHFDTAAHYETEAPIXXXXXXXXXXXXXXX 285 +G+GT V G D + R + A E G FDTA Y A Sbjct: 86 LGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYA--AGKAEVILGSIIKKKGWR 143 Query: 286 XDDLFITSKL-WCSDAHGDR------VVPALRHTLRNLQMEYVDLYLVHWPVSMKP 432 L IT+KL W A +R ++ L+ +L+ LQ+EYVD+ + P S P Sbjct: 144 RSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPDSNTP 199
>KCAB1_CHICK (Q9PWR1) Voltage-gated potassium channel beta-1 subunit (K(+)| channel beta-1 subunit) (Kv-beta-1) Length = 401 Score = 32.7 bits (73), Expect = 0.54 Identities = 34/116 (29%), Positives = 49/116 (42%), Gaps = 10/116 (8%) Frame = +1 Query: 115 IGMGTAVQ--GPKPDPIRRAVLR-AIEIGYRHFDTAAHYETEAPIXXXXXXXXXXXXXXX 285 +G+GT V G D + ++ A E G FDTA Y A Sbjct: 86 LGLGTWVTFGGQISDEVAEQLMTIAYESGVNLFDTAEVYA--AGKAEVILGNILKKKGWR 143 Query: 286 XDDLFITSKL-WCSDAHGDR------VVPALRHTLRNLQMEYVDLYLVHWPVSMKP 432 L IT+KL W A +R ++ LR +L+ LQ+EYVD+ + P + P Sbjct: 144 RSSLVITTKLYWGGKAETERGLSRKHIIEGLRASLQRLQLEYVDVVFANRPDNNTP 199
>ICP0_HHV11 (P08393) Trans-acting transcriptional protein ICP0 (Immediate-early| protein IE110) (VMW110) (Alpha-0 protein) Length = 775 Score = 32.0 bits (71), Expect = 0.92 Identities = 19/65 (29%), Positives = 24/65 (36%) Frame = +1 Query: 13 PASESQLPTQPFPSHTPSTQPMGAGDRTVAGMPRIGMGTAVQGPKPDPIRRAVLRAIEIG 192 PAS + P P P P P + + PR + V+ P P P RA E Sbjct: 369 PASPHRPPAAPMPGSAPRPGPPASAAASGPARPRAAVAPCVRAPPPGPGPRAPAPGAEPA 428 Query: 193 YRHFD 207 R D Sbjct: 429 ARPAD 433
>DHGP_ASPNG (P55804) NADP(+)-dependent glycerol dehydrogenase (EC 1.1.1.72)| (Fragments) Length = 99 Score = 31.2 bits (69), Expect = 1.6 Identities = 9/16 (56%), Positives = 16/16 (100%) Frame = +1 Query: 376 LQMEYVDLYLVHWPVS 423 L+++Y+DL+LVHWP++ Sbjct: 20 LKVDYIDLFLVHWPIA 35
>DMI1L_ORYSA (Q75LD5) Putative ion channel DMI1-like, chloroplast precursor| Length = 893 Score = 30.8 bits (68), Expect = 2.1 Identities = 17/49 (34%), Positives = 24/49 (48%) Frame = +1 Query: 10 LPASESQLPTQPFPSHTPSTQPMGAGDRTVAGMPRIGMGTAVQGPKPDP 156 LP+S ++ P PFPS + S+ P DR PR + + P P P Sbjct: 25 LPSSRARTPRAPFPSTSRSSNPYSFPDRRPPPTPR----SRSRSPLPPP 69
>RGL2_HUMAN (O15211) Ral guanine nucleotide dissociation stimulator-like 2| (RalGDS-like factor) (RAS-associated protein RAB2L) Length = 777 Score = 30.8 bits (68), Expect = 2.1 Identities = 17/40 (42%), Positives = 20/40 (50%) Frame = -3 Query: 429 LHGYRPVDEVQVHVLHLEIPERVPEGGDDPVAVRVAAPEL 310 L G RP+ E Q H + E+ P G DP A RV P L Sbjct: 492 LQGLRPLTEAQSHRVSCEVE---PPGSSDPPAPRVLRPTL 528
>AMPA_PROAC (Q6A9W5) Probable cytosol aminopeptidase (EC 3.4.11.1) (Leucine| aminopeptidase) (LAP) (Leucyl aminopeptidase) Length = 508 Score = 30.8 bits (68), Expect = 2.1 Identities = 19/53 (35%), Positives = 26/53 (49%) Frame = +1 Query: 10 LPASESQLPTQPFPSHTPSTQPMGAGDRTVAGMPRIGMGTAVQGPKPDPIRRA 168 L A+ +QLP +P P S GA D +AG+ G VQG P ++ A Sbjct: 5 LVANSTQLPIRPRPDLKVSRNANGA-DVVIAGLVEGSQGPTVQGLAPRAVKEA 56
>YQKF_BACSU (P54569) Hypothetical oxidoreductase yqkF (EC 1.-.-.-)| Length = 306 Score = 30.4 bits (67), Expect = 2.7 Identities = 27/120 (22%), Positives = 48/120 (40%), Gaps = 8/120 (6%) Frame = +1 Query: 76 MGAGDRTVAGMPRIGMGTAVQGPKPDPIRRAVLRAIEIGYRHFDTAAHYET--------E 231 +G D ++ +G+G G + + + AIE+G + DTA Y+ + Sbjct: 6 LGTSDLDIS---EVGLGCMSLGTEKNKALSILDEAIELGINYLDTADLYDRGRNEEIVGD 62 Query: 232 APIXXXXXXXXXXXXXXXXDDLFITSKLWCSDAHGDRVVPALRHTLRNLQMEYVDLYLVH 411 A DD S+ W D + A++ +L L+ +Y+DLY +H Sbjct: 63 AIQNRRHDIILATKAGNRWDD---GSEGWYWDPSKAYIKEAVKKSLTRLKTDYIDLYQLH 119
>RS10_TROWT (Q83FY5) 30S ribosomal protein S10| Length = 102 Score = 30.4 bits (67), Expect = 2.7 Identities = 12/34 (35%), Positives = 20/34 (58%) Frame = +1 Query: 124 GTAVQGPKPDPIRRAVLRAIEIGYRHFDTAAHYE 225 G + GP P P +++V+ I +RH D+ H+E Sbjct: 33 GATIVGPVPLPTKKSVVCVIRSPHRHKDSREHFE 66
>RS10_TROW8 (Q83I79) 30S ribosomal protein S10| Length = 102 Score = 30.4 bits (67), Expect = 2.7 Identities = 12/34 (35%), Positives = 20/34 (58%) Frame = +1 Query: 124 GTAVQGPKPDPIRRAVLRAIEIGYRHFDTAAHYE 225 G + GP P P +++V+ I +RH D+ H+E Sbjct: 33 GATIVGPVPLPTKKSVVCVIRSPHRHKDSREHFE 66
>YGHZ_ECOLI (Q46851) Hypothetical protein yghZ| Length = 346 Score = 30.0 bits (66), Expect = 3.5 Identities = 25/94 (26%), Positives = 44/94 (46%), Gaps = 10/94 (10%) Frame = +1 Query: 160 RRAVLR-AIEIGYRHFDTAAHY-ETEAPIXXXXXXXXXXXXXXXXDDLFITSK----LWC 321 +RA+LR A ++G HFD A +Y D+L I++K +W Sbjct: 45 QRAILRKAFDLGITHFDLANNYGPPPGSAEENFGRLLREDFAAYRDELIISTKAGYDMWP 104 Query: 322 SD--AHGDR--VVPALRHTLRNLQMEYVDLYLVH 411 + G R ++ +L +L+ + +EYVD++ H Sbjct: 105 GPYGSGGSRKYLLASLDQSLKRMGLEYVDIFYSH 138
>YGHZ_ECO57 (Q8X529) Hypothetical protein yghZ| Length = 346 Score = 30.0 bits (66), Expect = 3.5 Identities = 25/94 (26%), Positives = 44/94 (46%), Gaps = 10/94 (10%) Frame = +1 Query: 160 RRAVLR-AIEIGYRHFDTAAHY-ETEAPIXXXXXXXXXXXXXXXXDDLFITSK----LWC 321 +RA+LR A ++G HFD A +Y D+L I++K +W Sbjct: 45 QRAILRKAFDLGITHFDLANNYGPPPGSAEENFGRLLREDFAAYRDELIISTKAGYDMWP 104 Query: 322 SD--AHGDR--VVPALRHTLRNLQMEYVDLYLVH 411 + G R ++ +L +L+ + +EYVD++ H Sbjct: 105 GPYGSGGSRKYLLASLDQSLKRMGLEYVDIFYSH 138
>KCAB_ORYSA (Q40648) Probable voltage-gated potassium channel beta subunit| (K(+) channel beta subunit) Length = 328 Score = 30.0 bits (66), Expect = 3.5 Identities = 17/54 (31%), Positives = 28/54 (51%), Gaps = 7/54 (12%) Frame = +1 Query: 292 DLFITSKL-WCSDAHGDR------VVPALRHTLRNLQMEYVDLYLVHWPVSMKP 432 D+ +++KL W D+ +V LR +L+ L M+YVD+ H P + P Sbjct: 76 DVVVSTKLFWGGQGPNDKGLSRKHIVEGLRGSLKRLDMDYVDVVYCHRPDATTP 129
>XRCC1_HUMAN (P18887) DNA-repair protein XRCC1 (X-ray repair cross-complementing| protein 1) Length = 633 Score = 30.0 bits (66), Expect = 3.5 Identities = 19/50 (38%), Positives = 25/50 (50%), Gaps = 1/50 (2%) Frame = +1 Query: 10 LPASESQLPTQPFPSHTPSTQPMGA-GDRTVAGMPRIGMGTAVQGPKPDP 156 L S + P P P+ TP+T P+ A V G PR G GT + P+ P Sbjct: 265 LSPSVPKRPKLPAPTRTPATAPVPARAQGAVTGKPR-GEGTEPRRPRAGP 313
>RL15_CORGL (Q8NSX2) 50S ribosomal protein L15| Length = 148 Score = 29.6 bits (65), Expect = 4.6 Identities = 18/51 (35%), Positives = 30/51 (58%), Gaps = 6/51 (11%) Frame = -3 Query: 453 EGGLEP-----PGLHGYRPVDEVQVHVLHL-EIPERVPEGGDDPVAVRVAA 319 EGG P P L G++ ++V V+++ ++ E+ P+GGD +A VAA Sbjct: 52 EGGQMPLQMRLPKLKGFKNPNKVDYQVVNIADLAEKFPQGGDVSIADIVAA 102
>YGY3_HALSQ (P21561) Hypothetical 50.6 kDa protein in the 5'region of gyrA and| gyrB (ORF 3) Length = 437 Score = 29.3 bits (64), Expect = 6.0 Identities = 16/38 (42%), Positives = 19/38 (50%), Gaps = 3/38 (7%) Frame = +3 Query: 384 GVRGPVPRPLAGIH---EARAVQGPLHGGGLRAVRHAG 488 G VPRPL H + R GP H GG++ HAG Sbjct: 393 GSTAAVPRPLPRQHLRRDGRGRAGPHHRGGMQRQPHAG 430
>ALKE_BABBO (P40690) Aldo-keto reductase (Fragment)| Length = 285 Score = 28.9 bits (63), Expect = 7.8 Identities = 10/27 (37%), Positives = 17/27 (62%) Frame = +1 Query: 337 DRVVPALRHTLRNLQMEYVDLYLVHWP 417 D ++ A+ +L L +Y+DL +HWP Sbjct: 29 DNILKAVDGSLSRLNTDYIDLLQLHWP 55
>UBP10_YEAST (P53874) Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15)| (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10) (Disrupter of telomere silencing protein 4) Length = 792 Score = 28.9 bits (63), Expect = 7.8 Identities = 15/47 (31%), Positives = 26/47 (55%) Frame = -1 Query: 476 NGTKSSAVKGALNRPGFMDTGQWTRYRSTYSIWRFRSVCLRAGTTLS 336 NGT SS +K A++ P F+D ++ + ++ SV + G +LS Sbjct: 642 NGTSSSKMKQAVSYPMFLDLTEYCESKELPVKYQLLSVVVHEGRSLS 688
>ATN1_RAT (P54258) Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein)| Length = 1183 Score = 28.9 bits (63), Expect = 7.8 Identities = 16/48 (33%), Positives = 21/48 (43%) Frame = +1 Query: 16 ASESQLPTQPFPSHTPSTQPMGAGDRTVAGMPRIGMGTAVQGPKPDPI 159 AS + QP P H PS MG G ++G+P P P P+ Sbjct: 316 ASPPGMGAQPIPGHLPSPHAMGQG---MSGLPPGPEKGPTLAPSPHPL 360
>ANR12_HUMAN (Q6UB98) Ankyrin repeat domain-containing protein 12 (Ankyrin| repeat-containing cofactor 2) (GAC-1 protein) Length = 2062 Score = 28.9 bits (63), Expect = 7.8 Identities = 15/41 (36%), Positives = 18/41 (43%) Frame = -3 Query: 465 VLRREGGLEPPGLHGYRPVDEVQVHVLHLEIPERVPEGGDD 343 +LR G HG RPVD + L L + VP DD Sbjct: 270 LLRHGGNAFQANKHGERPVDVAETEELELLLKREVPLSDDD 310 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 51,443,073 Number of Sequences: 219361 Number of extensions: 954727 Number of successful extensions: 4138 Number of sequences better than 10.0: 111 Number of HSP's better than 10.0 without gapping: 3845 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4055 length of database: 80,573,946 effective HSP length: 104 effective length of database: 57,760,402 effective search space used: 3465624120 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
