ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | bart34c09 |
|---|---|
| Clone Library Name | barley_pub |
>LEU32_ARATH (P93832) 3-isopropylmalate dehydrogenase 2, chloroplast precursor| (EC 1.1.1.85) (Beta-IPM dehydrogenase 2) (IMDH 2) (3-IPM-DH 2) Length = 405 Score = 215 bits (548), Expect = 6e-56 Identities = 107/142 (75%), Positives = 120/142 (84%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 ITLLPGDGIGPEVV++AK+VL AGS EGVE ++E VPLP+ET++AA+ Sbjct: 45 ITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVPLPEETISAAK 104 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 SDA+LLGAIGGYKWDNNEKHL+PE GLL IRA L VFANLRPATVLPQLVDASTLKREV Sbjct: 105 ESDAVLLGAIGGYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATVLPQLVDASTLKREV 164 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 AEGVD+MVVRELTGGIYFG+PR Sbjct: 165 AEGVDLMVVRELTGGIYFGEPR 186
>LEU3_BRANA (P29102) 3-isopropylmalate dehydrogenase, chloroplast precursor (EC| 1.1.1.85) (Beta-IPM dehydrogenase) (IMDH) (3-IPM-DH) Length = 406 Score = 214 bits (545), Expect = 1e-55 Identities = 106/142 (74%), Positives = 120/142 (84%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 ITLLPGDGIGPEV+++AK+VL AGS EG+E ++E VPLP+ET++AA+ Sbjct: 46 ITLLPGDGIGPEVISIAKNVLQQAGSLEGLEFSFQEMPVGGAALDLVGVPLPEETVSAAK 105 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 SDA+LLGAIGGYKWD NEKHLKPETGLL +RAGL VFANLRPATVLPQLVDASTLKREV Sbjct: 106 ESDAVLLGAIGGYKWDKNEKHLKPETGLLQLRAGLKVFANLRPATVLPQLVDASTLKREV 165 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 AEGVD+MVVRELTGGIYFG PR Sbjct: 166 AEGVDLMVVRELTGGIYFGVPR 187
>LEU31_ARATH (Q9SA14) 3-isopropylmalate dehydrogenase 1, chloroplast precursor| (EC 1.1.1.85) (Beta-IPM dehydrogenase 1) (IMDH 1) (3-IPM-DH 1) Length = 406 Score = 203 bits (517), Expect = 2e-52 Identities = 101/142 (71%), Positives = 116/142 (81%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 ITLLPGDGIGPEV++VAK+VL AG +G+E ++E VPLP+ET AA+ Sbjct: 46 ITLLPGDGIGPEVISVAKNVLQKAGFLQGLEFDFQEMPFGGAALDLVGVPLPEETSTAAK 105 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 SDAILLGAIGGYKWD NEKHL+PE GLLNIR L VFANLRPATVLPQLVDASTLK+EV Sbjct: 106 QSDAILLGAIGGYKWDKNEKHLRPEMGLLNIRRDLNVFANLRPATVLPQLVDASTLKKEV 165 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 A+GVD+M+VRELTGGIYFG+PR Sbjct: 166 AQGVDMMIVRELTGGIYFGEPR 187
>LEU33_ARATH (Q9FMT1) 3-isopropylmalate dehydrogenase 3, chloroplast precursor| (EC 1.1.1.85) (Beta-IPM dehydrogenase 3) (IMDH 3) (3-IPM-DH 3) Length = 409 Score = 200 bits (508), Expect = 3e-51 Identities = 100/142 (70%), Positives = 113/142 (79%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I LLPGDGIGPEV++VAK+VL AGS EG+E +KE VPLP+ET AA+ Sbjct: 49 IALLPGDGIGPEVISVAKNVLQKAGSLEGLEFDFKEMPVGGAALDLVGVPLPEETFTAAK 108 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 SDAILLGAIGGYKWD NEKHL+PE L +R L VFANLRPATVLPQLVDASTLK+EV Sbjct: 109 LSDAILLGAIGGYKWDKNEKHLRPEMALFYLRRDLKVFANLRPATVLPQLVDASTLKKEV 168 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 AEGVD+M+VRELTGGIYFG+PR Sbjct: 169 AEGVDMMIVRELTGGIYFGEPR 190
>LEU3_ANASP (Q8YXA2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 362 Score = 181 bits (459), Expect = 1e-45 Identities = 90/142 (63%), Positives = 104/142 (73%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 ITLLPGDGIGPE++AVA DVL G + ++ ++E PLP TL R Sbjct: 7 ITLLPGDGIGPEIMAVAVDVLKVVGQQFDIQFDFQEALIGGAAIDATGEPLPSATLDTCR 66 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 SDA+LL AIGGYKWD+ H +PE GLL +RAGL +FANLRPA +LPQL+DASTLKREV Sbjct: 67 HSDAVLLAAIGGYKWDSLPPHQRPEGGLLGLRAGLELFANLRPAQILPQLIDASTLKREV 126 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 EGVDIMVVRELTGGIYFGKPR Sbjct: 127 VEGVDIMVVRELTGGIYFGKPR 148
>LEU3_SYNP6 (Q5MZ40) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 365 Score = 181 bits (458), Expect = 2e-45 Identities = 88/142 (61%), Positives = 107/142 (75%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 ITLLPGDGIGPE++AV D+L A G + + ++E PLP+ TLA R Sbjct: 7 ITLLPGDGIGPEIMAVTVDILRAIGRQFDLNFEFEEALIGGSAIDATGEPLPEATLATCR 66 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 SDA+LL AIGGYKWD+ + +PETGLL +RAGLG+FANLRPA +LPQLVDAS+LKREV Sbjct: 67 NSDAVLLAAIGGYKWDSLPRSQRPETGLLGLRAGLGLFANLRPAAILPQLVDASSLKREV 126 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 EGVD+MVVRELTGGIYFG+P+ Sbjct: 127 IEGVDLMVVRELTGGIYFGEPK 148
>LEU3_SYNY3 (P73960) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 362 Score = 178 bits (451), Expect = 1e-44 Identities = 88/142 (61%), Positives = 104/142 (73%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 +TLLPGDGIGPE++AVA VL + G ++E PLP+ TLA A+ Sbjct: 7 VTLLPGDGIGPEIMAVAVAVLGKVADQFGFAFNFQEALIGGAAIDATGQPLPEATLAQAK 66 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 SDA+LL AIGGY WDN + +PETGLL IR GLG+FANLRPAT+ PQL+DAS+LKREV Sbjct: 67 DSDAVLLAAIGGYAWDNLPRSQRPETGLLAIREGLGLFANLRPATIFPQLIDASSLKREV 126 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 EGVDIMVVRELTGGIYFGKP+ Sbjct: 127 VEGVDIMVVRELTGGIYFGKPK 148
>LEU3_SPIPL (Q00412) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 355 Score = 166 bits (419), Expect = 5e-41 Identities = 84/142 (59%), Positives = 101/142 (71%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 ITLL GDGIGPE++AVA DVL A G + + +KE PLP+E+L A R Sbjct: 7 ITLLSGDGIGPEIMAVAVDVLKAVGKQLDLNFEFKEALMGGVAIDATGEPLPEESLQACR 66 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 SDA+LL AIGGYKWDN + +PETGLL +RAGLG+FAN P ++DAS+LKREV Sbjct: 67 DSDAVLLAAIGGYKWDNLPRPERPETGLLALRAGLGLFANRARLLFCPHVLDASSLKREV 126 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 EGVDIMVVRELTGGIYFG+P+ Sbjct: 127 VEGVDIMVVRELTGGIYFGQPK 148
>LEU3_SYNEL (P59029) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 361 Score = 160 bits (405), Expect = 2e-39 Identities = 81/142 (57%), Positives = 100/142 (70%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +L GDGIGPE+ AVA DVL A + G++ + PLP TLA R Sbjct: 7 IAVLAGDGIGPEITAVALDVLRAIAPRFGLDFDFVPALVGGCAIDAVGEPLPAATLATCR 66 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 SDA+LL AIGG +WD+ +HL+PETGLL +R+GLG+FANLRPA + PQL+ AS+LK EV Sbjct: 67 QSDAVLLAAIGGTQWDSLPRHLRPETGLLALRSGLGLFANLRPAKIFPQLLHASSLKPEV 126 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 GVD+MVVRELTGGIYFG+PR Sbjct: 127 IAGVDLMVVRELTGGIYFGQPR 148
>LEU3_PROMM (Q7V842) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 357 Score = 157 bits (398), Expect = 1e-38 Identities = 79/142 (55%), Positives = 102/142 (71%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I LLPGDGIGPE+ AVAK +L A G + G +L +++ PLP TL A + Sbjct: 6 IVLLPGDGIGPEITAVAKLLLDALGHQHGFKLNFEQHPIGGVAIDASGSPLPASTLEACQ 65 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 ASDA+LL AIG ++D + +PETGLL++RAGL +FANLRP T+LP L+DAS+LK V Sbjct: 66 ASDAVLLAAIGSPRFDALPREQRPETGLLSLRAGLKLFANLRPVTILPALIDASSLKANV 125 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 +GVD+MVVRELTGGIYFG+P+ Sbjct: 126 IKGVDLMVVRELTGGIYFGQPK 147
>LEU3_PSEF5 (Q4KF05) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 360 Score = 157 bits (397), Expect = 2e-38 Identities = 79/142 (55%), Positives = 96/142 (67%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +LPGDGIGPE++A A VL A K + VPL DETL AR Sbjct: 5 ILILPGDGIGPEIMAEAVKVLELANDKYSLGFELSHDVIGGAAIDKHGVPLADETLDRAR 64 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 A+DA+LLGA+GG KWD E+ ++PE GLL IRA LG+F NLRPA + PQL DAS+LK E+ Sbjct: 65 AADAVLLGAVGGPKWDKIERDIRPERGLLKIRAQLGLFGNLRPAILYPQLADASSLKPEI 124 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 G+DI++VRELTGGIYFG PR Sbjct: 125 VSGLDILIVRELTGGIYFGAPR 146
>LEU3_BACHD (Q9K8E9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 155 bits (393), Expect = 6e-38 Identities = 77/142 (54%), Positives = 94/142 (66%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +LPGDGIGPEV A +VL A + G YK+ PLP+ETL R Sbjct: 5 IAVLPGDGIGPEVTDAAIEVLQAVADRFGHTFSYKKALLGGCAIDEVGTPLPEETLDVCR 64 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 +D ILLGA+GG KWD HL+PE GLL +R GL +FANLRP TV L DASTLK +V Sbjct: 65 HADGILLGAVGGPKWDTLPGHLRPEKGLLGLRKGLNLFANLRPVTVYDSLADASTLKNDV 124 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 +GVD+++VRELTGG+YFG+PR Sbjct: 125 IDGVDLLIVRELTGGLYFGEPR 146
>LEU3_PSEU2 (Q4ZUZ4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 360 Score = 154 bits (390), Expect = 1e-37 Identities = 78/142 (54%), Positives = 95/142 (66%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +LPGDGIGPE++ A VL A K + VPL DETL AR Sbjct: 5 ILILPGDGIGPEIMTEAVKVLELANEKYQLGFELTHDVIGGAAIDKHGVPLADETLERAR 64 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 A+DA+LLGA+GG KWD E+ ++PE GLL IR+ LG+F NLRPA + PQL DAS+LK E+ Sbjct: 65 AADAVLLGAVGGPKWDTIERDIRPERGLLKIRSQLGLFGNLRPAILYPQLADASSLKPEI 124 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 G+DIM+VRELTGGIYFG PR Sbjct: 125 VAGLDIMIVRELTGGIYFGAPR 146
>LEU3_PSEPK (Q88LE5) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 360 Score = 154 bits (389), Expect = 2e-37 Identities = 78/142 (54%), Positives = 96/142 (67%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +LPGDGIGPE++A A VL A K + VPL DETL AR Sbjct: 5 ILILPGDGIGPEIMAEAVKVLELANDKFQLGFSLAHDVIGGAAIDKHGVPLADETLERAR 64 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 +DA+LLGA+GG KWD E+ ++PE GLL IR+ LG+FANLRPA + PQL DAS+LK E+ Sbjct: 65 KADAVLLGAVGGPKWDKIERDIRPERGLLKIRSQLGLFANLRPAILYPQLADASSLKPEI 124 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 G+DI++VRELTGGIYFG PR Sbjct: 125 VSGLDILIVRELTGGIYFGAPR 146
>LEU3_PSESM (Q884C0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 360 Score = 153 bits (386), Expect = 4e-37 Identities = 77/142 (54%), Positives = 95/142 (66%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +LPGDGIGPE++ A VL A K + VPL DETL AR Sbjct: 5 ILILPGDGIGPEIMTEAVKVLELANQKYQLGFELTHDVIGGAAIDKHGVPLADETLDRAR 64 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 A+DA+LLGA+GG KWD E+ ++PE GLL IR+ LG+F NLRPA + PQL DAS+LK E+ Sbjct: 65 AADAVLLGAVGGPKWDTIERDIRPERGLLKIRSQLGLFGNLRPAILYPQLADASSLKPEI 124 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 G+DI++VRELTGGIYFG PR Sbjct: 125 VAGLDILIVRELTGGIYFGAPR 146
>LEU3_PSE14 (Q48K97) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 360 Score = 153 bits (386), Expect = 4e-37 Identities = 77/142 (54%), Positives = 95/142 (66%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +LPGDGIGPE++ A VL A K + VPL DETL AR Sbjct: 5 ILILPGDGIGPEIMTEAVKVLELANEKYQLGFELTHDVIGGAAIDKHGVPLADETLDRAR 64 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 A+DA+LLGA+GG KWD E+ ++PE GLL IR+ LG+F NLRPA + PQL DAS+LK E+ Sbjct: 65 AADAVLLGAVGGPKWDTIERDIRPERGLLKIRSQLGLFGNLRPAILYPQLADASSLKPEI 124 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 G+DI++VRELTGGIYFG PR Sbjct: 125 VAGLDILIVRELTGGIYFGAPR 146
>LEU3_NITOC (Q3JCC4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 362 Score = 152 bits (384), Expect = 6e-37 Identities = 78/142 (54%), Positives = 99/142 (69%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I LL GDGIGPE++A A VL+A G +++ + PLP ETLA A+ Sbjct: 5 IALLAGDGIGPEIIAEAVKVLAALGEHGELDVVLESGLIGGAAYEVTGTPLPAETLALAQ 64 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 SDAILLGA+GG +W+ + ++PE GLL IR+ LG+FANLRPA + PQLV ASTLK EV Sbjct: 65 DSDAILLGAVGGPQWETLDIKVRPEKGLLGIRSALGLFANLRPAILYPQLVGASTLKPEV 124 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 G+D+M+VRELTGGIYFG+PR Sbjct: 125 VSGLDLMIVRELTGGIYFGQPR 146
>LEU3_XYLFA (Q9PAX3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 357 Score = 152 bits (383), Expect = 8e-37 Identities = 79/142 (55%), Positives = 96/142 (67%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +LPGDGIG E+VA A VL + + LR PL DETLA AR Sbjct: 5 ILILPGDGIGHEIVAEAVKVLEHVNVRHTLNLRLSFDALGGAAYEKYGSPLADETLARAR 64 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 +DA+LLGA+GG +WD + L+PE GLL IRA LG+FANLRPA + PQL DASTLK EV Sbjct: 65 DADAVLLGAVGGPQWDTIDPALRPERGLLKIRAQLGLFANLRPALLYPQLADASTLKPEV 124 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 G+DI++VRELTGG+YFG+PR Sbjct: 125 VAGLDILIVRELTGGLYFGQPR 146
>LEU3_XANOR (Q5H4C7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 357 Score = 152 bits (383), Expect = 8e-37 Identities = 80/144 (55%), Positives = 101/144 (70%), Gaps = 2/144 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGV--ELRYKEXXXXXXXXXXXXVPLPDETLAA 308 I +LPGDGIGPE++A A VL ++ G+ EL Y E PL DETL Sbjct: 5 ILILPGDGIGPEIMAEAVKVLQRIDTQHGLGFELVYDELGGAAYDKYGS--PLADETLER 62 Query: 309 ARASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKR 488 ARA+DA+LLGA+GG +WD + L+PE GLL IR+ LG+FANLRPA + PQL DASTLK Sbjct: 63 ARAADAVLLGAVGGPQWDTIDPSLRPERGLLKIRSQLGLFANLRPALLYPQLADASTLKP 122 Query: 489 EVAEGVDIMVVRELTGGIYFGKPR 560 EV G+D++++RELTGGIYFG+PR Sbjct: 123 EVVAGLDLLILRELTGGIYFGQPR 146
>LEU3_XANC5 (Q3BPJ8) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 357 Score = 152 bits (383), Expect = 8e-37 Identities = 80/144 (55%), Positives = 101/144 (70%), Gaps = 2/144 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGV--ELRYKEXXXXXXXXXXXXVPLPDETLAA 308 I +LPGDGIGPE++A A VL ++ G+ EL Y E PL DETL Sbjct: 5 ILILPGDGIGPEIMAEAVKVLKRIDAQHGLGFELVYDELGGAAYDKYGS--PLADETLER 62 Query: 309 ARASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKR 488 ARA+DA+LLGA+GG +WD + L+PE GLL IR+ LG+FANLRPA + PQL DASTLK Sbjct: 63 ARAADAVLLGAVGGPQWDTIDPSLRPERGLLKIRSQLGLFANLRPALLYPQLADASTLKP 122 Query: 489 EVAEGVDIMVVRELTGGIYFGKPR 560 EV G+D++++RELTGGIYFG+PR Sbjct: 123 EVVAGLDLLILRELTGGIYFGQPR 146
>LEU3_PSEAE (Q51375) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 360 Score = 151 bits (382), Expect = 1e-36 Identities = 77/142 (54%), Positives = 97/142 (68%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +LPGDGIGPE++A A VL A + + E VPL D+TL AR Sbjct: 5 ILVLPGDGIGPEIMAEAVKVLELANDRFQLGFELAEDVIGGAAIDKHGVPLADQTLQRAR 64 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 +DA+LLGA+GG KWD E+ ++PE GLL IR+ LG+FANLRPA + PQL AS+LK EV Sbjct: 65 QADAVLLGAVGGPKWDRIERDIRPERGLLKIRSQLGLFANLRPAILYPQLAAASSLKPEV 124 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 G+DI++VRELTGGIYFG+PR Sbjct: 125 VAGLDILIVRELTGGIYFGQPR 146
>LEU3_XYLFT (Q87BQ1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 357 Score = 151 bits (382), Expect = 1e-36 Identities = 78/142 (54%), Positives = 96/142 (67%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +LPGDGIG E+VA A VL + + +R PL DETLA AR Sbjct: 5 ILILPGDGIGHEIVAEAVKVLEHVNVRHTLNMRLSFDALGGAAYEKYGSPLADETLARAR 64 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 +DA+LLGA+GG +WD + L+PE GLL IRA LG+FANLRPA + PQL DASTLK EV Sbjct: 65 EADAVLLGAVGGPQWDTIDPALRPERGLLKIRAQLGLFANLRPALLYPQLADASTLKPEV 124 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 G+DI++VRELTGG+YFG+PR Sbjct: 125 VAGLDILIVRELTGGLYFGQPR 146
>LEU3_CHLTE (P59028) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 352 Score = 151 bits (381), Expect = 1e-36 Identities = 80/142 (56%), Positives = 92/142 (64%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +PGDGIGPEVVA A DVL+A K G E+ +E L DETL A + Sbjct: 5 IVSIPGDGIGPEVVAGALDVLNAVAKKHGFEVSVEEHLFGGASYDVHGSMLTDETLEACK 64 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 DA+LLGA+GGYKW+N KPE LL IR LG+FANLRPA V LV +STLK EV Sbjct: 65 NCDAVLLGAVGGYKWENLPHDKKPEAALLKIRKELGLFANLRPARVYDALVASSTLKTEV 124 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 +G D MV RELTGGIYFG+PR Sbjct: 125 VQGTDFMVFRELTGGIYFGQPR 146
>LEU3_XANCP (Q8P5L1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 357 Score = 151 bits (381), Expect = 1e-36 Identities = 80/144 (55%), Positives = 101/144 (70%), Gaps = 2/144 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKE--GVELRYKEXXXXXXXXXXXXVPLPDETLAA 308 I +LPGDGIGPE++A A VL+ ++ GV L Y E PL DETL Sbjct: 5 ILILPGDGIGPEIMAEAVKVLTRIDTQHTLGVTLVYDELGGAAYDKYGS--PLADETLER 62 Query: 309 ARASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKR 488 ARA+DA+LLGA+GG +WD + L+PE GLL IR+ LG+FANLRPA + PQL DASTLK Sbjct: 63 ARAADAVLLGAVGGPQWDTIDPALRPERGLLKIRSQLGLFANLRPALLYPQLADASTLKP 122 Query: 489 EVAEGVDIMVVRELTGGIYFGKPR 560 EV G+D++++RELTGGIYFG+PR Sbjct: 123 EVVSGLDLLILRELTGGIYFGQPR 146
>LEU3_XANC8 (Q4UYG2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 357 Score = 151 bits (381), Expect = 1e-36 Identities = 80/144 (55%), Positives = 101/144 (70%), Gaps = 2/144 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKE--GVELRYKEXXXXXXXXXXXXVPLPDETLAA 308 I +LPGDGIGPE++A A VL+ ++ GV L Y E PL DETL Sbjct: 5 ILILPGDGIGPEIMAEAVKVLTRIDTQHTLGVTLVYDELGGAAYDKYGS--PLADETLER 62 Query: 309 ARASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKR 488 ARA+DA+LLGA+GG +WD + L+PE GLL IR+ LG+FANLRPA + PQL DASTLK Sbjct: 63 ARAADAVLLGAVGGPQWDTIDPALRPERGLLKIRSQLGLFANLRPALLYPQLADASTLKP 122 Query: 489 EVAEGVDIMVVRELTGGIYFGKPR 560 EV G+D++++RELTGGIYFG+PR Sbjct: 123 EVVSGLDLLILRELTGGIYFGQPR 146
>LEU3_WOLSU (Q7M886) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 358 Score = 150 bits (380), Expect = 2e-36 Identities = 74/142 (52%), Positives = 94/142 (66%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I ++ GDGIGPE+V AK VL A G EL Y + VPLPDET+ Sbjct: 6 IAIIKGDGIGPEIVDEAKKVLDAISYSHGFELSYHDYLMGGIAVDRAGVPLPDETIEGCL 65 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 +DA+L GAIGG KWD+ + L+PE+GLL +R L +FANLRP V +L++ASTLK V Sbjct: 66 RADAVLFGAIGGEKWDSLPRELRPESGLLKLRKSLEIFANLRPTVVYDELIEASTLKESV 125 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 +GVDI+VVREL GGIYFG+P+ Sbjct: 126 IKGVDILVVRELIGGIYFGEPK 147
>LEU3_SYNPX (Q7U840) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 357 Score = 150 bits (379), Expect = 2e-36 Identities = 73/142 (51%), Positives = 98/142 (69%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 + LLPGDGIGPE+ AVA+ +L A + G EL + PLP TL A + Sbjct: 6 VVLLPGDGIGPEITAVARQLLEAVSQRHGFELCFDGQLIGGSAIDACGEPLPASTLDACK 65 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 A+DA+LL AIG ++DN + +PETGLL +R+G+ +FANLRP ++P L+ AS+L+ EV Sbjct: 66 AADAVLLAAIGSPRFDNLPRDKRPETGLLGLRSGMALFANLRPVKIVPALIGASSLRPEV 125 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 EGVD+MVVRELTGGIYFG+P+ Sbjct: 126 IEGVDLMVVRELTGGIYFGQPK 147
>LEU3_PSYAR (Q4FRV0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 367 Score = 150 bits (378), Expect = 3e-36 Identities = 75/142 (52%), Positives = 99/142 (69%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I L GDGIGPE++ A DVL+A +K + L + PLP+ETL AR Sbjct: 4 ILTLAGDGIGPEIMTQAIDVLNAVNNKFALGLTLESGLIGGVAVDATGEPLPEETLQRAR 63 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 A+DA+LLGA+GG KWD E+ +PE GLL IR+ LG+FANLR A + PQLV+AS++K E+ Sbjct: 64 AADAVLLGAVGGPKWDGIERSKRPERGLLKIRSELGLFANLRVAKLYPQLVNASSIKPEI 123 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 G+D+++VRELTGGIYFG+PR Sbjct: 124 ISGLDLLIVRELTGGIYFGEPR 145
>LEU3_METCA (Q606F4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 360 Score = 150 bits (378), Expect = 3e-36 Identities = 77/142 (54%), Positives = 95/142 (66%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +LPGDGIGPE+VA A VL S G+ + + P P ETL R Sbjct: 5 IAVLPGDGIGPEIVAEALKVLDCLRSDFGLAVETEHALIGGAAYDAHGTPFPKETLELCR 64 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 A+D+ILLGA+GG KW+ + L+PE GLL +R+ L +F+NLRPA + PQLV ASTLK EV Sbjct: 65 AADSILLGAVGGPKWEPLDYSLRPERGLLGLRSELELFSNLRPAVLYPQLVSASTLKPEV 124 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 G+DIM+VRELTGGIYFGKPR Sbjct: 125 VAGLDIMIVRELTGGIYFGKPR 146
>LEU3_XANAC (Q8PH05) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 357 Score = 149 bits (377), Expect = 4e-36 Identities = 75/142 (52%), Positives = 97/142 (68%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +LPGDGIGPE++A A VL ++ G+ + PL DETL AR Sbjct: 5 ILILPGDGIGPEIMAEAVKVLKRIDAQHGLGFQLVYDELGGTAYDKYGSPLADETLERAR 64 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 +DA+LLGA+GG +WD + L+PE GLL IR+ LG+FANLRPA + PQL DASTLK EV Sbjct: 65 GADAVLLGAVGGPQWDTIDPALRPERGLLKIRSQLGLFANLRPALLYPQLADASTLKPEV 124 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 G+D++++RELTGGIYFG+PR Sbjct: 125 VAGLDLLILRELTGGIYFGQPR 146
>LEU3_BACLD (Q65GI9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 370 Score = 148 bits (373), Expect = 1e-35 Identities = 76/141 (53%), Positives = 90/141 (63%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I LLPGDGIGPEV+ A DVL + E ++ PLP+ET+AA + Sbjct: 5 IALLPGDGIGPEVLDAAVDVLKSVAEHYQHEFEFEYGLIGGAAIDEAGAPLPEETVAACK 64 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 A+DAILLGA+GG KWD N L+PE GLL IR L +FANLRP V L AS LK E Sbjct: 65 AADAILLGAVGGPKWDQNPSELRPEKGLLAIRKQLDLFANLRPVKVFESLAGASPLKTEY 124 Query: 495 AEGVDIMVVRELTGGIYFGKP 557 EGVD ++VRELTGG+YFGKP Sbjct: 125 IEGVDFVIVRELTGGLYFGKP 145
>LEU3_BACSK (Q5WEN4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 364 Score = 145 bits (367), Expect = 6e-35 Identities = 75/142 (52%), Positives = 91/142 (64%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I LLPGDGIGPE++A K VL ++ E PLP+ETL A+ Sbjct: 5 ILLLPGDGIGPEIIAETKRVLEEIARLYHHTFQFVEGRIGGDAIDATGSPLPEETLDLAK 64 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 SDAILLGA+GG KWD N +PE GLL IR LG++ANLRP VL L+ ASTLK EV Sbjct: 65 GSDAILLGAVGGPKWDGNAPEKRPEKGLLQIRKALGLYANLRPVRVLKPLMGASTLKEEV 124 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 VD+++VRELTGG+YFG+PR Sbjct: 125 LADVDLLIVRELTGGLYFGEPR 146
>LEU3_GLOVI (Q7NFH4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 362 Score = 145 bits (367), Expect = 6e-35 Identities = 75/142 (52%), Positives = 92/142 (64%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +LPGDGIG E+V V +L AA + ++E PLP TL + Sbjct: 7 IAVLPGDGIGTEIVQVGVAMLEAAARRFDFAFDFEEAPIGGAAIDATGEPLPAATLELCK 66 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 ASDA+ LGA+GG +WD +PE LL +RAGLG+FANLRPA +LPQLV AS LK EV Sbjct: 67 ASDAVFLGAVGGPQWDTLPSDKRPEKALLGLRAGLGLFANLRPARILPQLVAASALKPEV 126 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 EGVDI+VVRELTGG+YFG P+ Sbjct: 127 VEGVDILVVRELTGGLYFGIPK 148
>LEU3_GEOKA (Q5KWJ4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 371 Score = 145 bits (365), Expect = 1e-34 Identities = 73/141 (51%), Positives = 92/141 (65%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +LPGDGIG EV + A +VL A G + G E ++ PLP+ETL R Sbjct: 6 IAVLPGDGIGKEVTSGAVEVLKAVGIRFGHEFTFEYGLIGGAAIDEAGTPLPEETLRLCR 65 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 SDA+LLGA+GG KWD+N HL+PE GLL IR L ++ANLRP LV AS LK ++ Sbjct: 66 ESDAVLLGAVGGPKWDDNPPHLRPEKGLLAIRKQLDLYANLRPVVCYDSLVSASPLKPDL 125 Query: 495 AEGVDIMVVRELTGGIYFGKP 557 +GVD ++VRELTGGIYFG+P Sbjct: 126 VQGVDFVIVRELTGGIYFGQP 146
>LEU3_PROMA (Q7VC80) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 362 Score = 144 bits (364), Expect = 1e-34 Identities = 71/142 (50%), Positives = 98/142 (69%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 ITLL GDGIGPE+ VAK +L+A K + +E PLP++TL + + Sbjct: 6 ITLLTGDGIGPEISIVAKKILAALSEKHSITFTIEEKPFGGQAIELTGKPLPEDTLNSCK 65 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 ASDA+LL AIG K+D+ + L+PETGLLN+RAGL +FAN+RP + L+ +S+LK E+ Sbjct: 66 ASDAVLLAAIGDPKYDDLPRDLRPETGLLNLRAGLNLFANIRPIKIRQALISSSSLKSEI 125 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 + VD++VVRELTGGIYFG+P+ Sbjct: 126 IKDVDLVVVRELTGGIYFGQPK 147
>LEU3_ACIAD (Q6FEV6) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 359 Score = 144 bits (362), Expect = 2e-34 Identities = 72/142 (50%), Positives = 94/142 (66%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +L GDGIGPE+V A+ VL+ K + L ++ P P T A+ Sbjct: 5 ILILAGDGIGPEIVGAAEQVLTKVNEKFELGLTWEHGLLGGSAIDAHGEPYPAVTSEQAK 64 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 +DAILLGA+GG KWD E+ ++PE GLL IR+ L +FANLRPA + PQL DAS+LK E+ Sbjct: 65 KADAILLGAVGGPKWDTIERSIRPERGLLKIRSELNLFANLRPALLYPQLADASSLKPEI 124 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 G+DI++VRELTGGIYFG+PR Sbjct: 125 VAGLDILIVRELTGGIYFGQPR 146
>LEU3_OCEIH (Q8EN68) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 366 Score = 142 bits (359), Expect = 5e-34 Identities = 71/141 (50%), Positives = 90/141 (63%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I LLPGDGIG E++ AK VL+A S+ ++E PLPD+T+ A Sbjct: 5 IILLPGDGIGREIIDSAKQVLTAIASEYNHRFTFEEHAIGGSAIDEYGTPLPDKTVDACS 64 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 +DAILLGA+GG KWD N HL+PE GLL IR LG+FANLRP + L+ AS LK E+ Sbjct: 65 KADAILLGAVGGPKWDANPSHLRPEKGLLGIRKQLGLFANLRPVKTISSLLYASPLKEEI 124 Query: 495 AEGVDIMVVRELTGGIYFGKP 557 D++++RELTGGIYFG P Sbjct: 125 VSQADMLIIRELTGGIYFGTP 145
>LEU3_BACSU (P05645) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 365 Score = 142 bits (358), Expect = 6e-34 Identities = 72/141 (51%), Positives = 91/141 (64%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I LLPGDGIGPEV+ A DVL + + E ++ PLP+ET+AA + Sbjct: 5 IALLPGDGIGPEVLESATDVLKSVAERFNHEFEFEYGLIGGAAIDEHHNPLPEETVAACK 64 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 +DAILLGA+GG KWD N L+PE GLL+IR L +FANLRP V L D S LK+E Sbjct: 65 NADAILLGAVGGPKWDQNLSELRPEKGLLSIRKQLDLFANLRPVKVFESLSDRSPLKKEY 124 Query: 495 AEGVDIMVVRELTGGIYFGKP 557 + VD ++VRELTGG+YFG+P Sbjct: 125 IDNVDFVIVRELTGGLYFGQP 145
>LEU3_BACCO (P12010) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 366 Score = 142 bits (358), Expect = 6e-34 Identities = 71/141 (50%), Positives = 91/141 (64%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 + +LPGDGIGPEV+ A VL +G E ++ PLP+ETL R Sbjct: 5 LAVLPGDGIGPEVMDAAIRVLKTVLDNDGHEAVFENALIGGAAIDEAGTPLPEETLDICR 64 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 SDAILLGA+GG KWD+N L+PE GLL +R +G+FANLRP L++AS LKRE Sbjct: 65 RSDAILLGAVGGPKWDHNPASLRPEKGLLGLRKEMGLFANLRPVKAYATLLNASPLKRER 124 Query: 495 AEGVDIMVVRELTGGIYFGKP 557 E VD+++VRELTGG+YFG+P Sbjct: 125 VENVDLVIVRELTGGLYFGRP 145
>LEU3_PROMT (Q46LE2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 359 Score = 142 bits (357), Expect = 8e-34 Identities = 68/142 (47%), Positives = 92/142 (64%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 ITLLPGDGIGPE+ V +L K G E+++KE +P PD TL + Sbjct: 6 ITLLPGDGIGPEITNVTHKILDLVSRKFGFEIKFKEMPFGGSAIDSDGIPFPDRTLQECK 65 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 SDA+LL AIG K+D + +PETGLLN+R+ L +FAN+RP ++P L AS+LK + Sbjct: 66 NSDAVLLAAIGDPKYDELPREKRPETGLLNLRSSLDLFANIRPVKIIPSLTKASSLKEDF 125 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 + VD++VVRELT GIYFG+P+ Sbjct: 126 VKEVDLVVVRELTSGIYFGEPK 147
>LEU3_BACCA (P05644) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 366 Score = 142 bits (357), Expect = 8e-34 Identities = 71/141 (50%), Positives = 91/141 (64%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +LPGDGIG EV + A +VL A G + G E ++ PLP+ET+ R Sbjct: 6 IAVLPGDGIGKEVTSGAVEVLKAVGIRFGHEFTFEYGLIGGAAIDEAGTPLPEETVRLCR 65 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 SDA+LLGA+GG KWD+N HL+PE GLL IR L ++ANLRP LV S LK ++ Sbjct: 66 ESDAVLLGAVGGPKWDDNPPHLRPEKGLLAIRKQLDLYANLRPVVCYDSLVSRSPLKPDL 125 Query: 495 AEGVDIMVVRELTGGIYFGKP 557 +GVD ++VRELTGGIYFG+P Sbjct: 126 VQGVDFVIVRELTGGIYFGQP 146
>LEU3_AQUAE (O66607) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 364 Score = 140 bits (354), Expect = 2e-33 Identities = 73/142 (51%), Positives = 90/142 (63%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +L GDGIGPE+V A VL G GVE Y+E PLP+ETL + Sbjct: 6 IAVLKGDGIGPEIVEQALRVLDKIGEIYGVEFEYREGLIGGEAIDKTGDPLPEETLKICK 65 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 SDAILLGA+GG KWDN +PE GLL IR L ++ANLRPA V L+ +S LK EV Sbjct: 66 ESDAILLGAVGGPKWDNLPTDKRPEKGLLRIRKELDLYANLRPAKVWDALISSSPLKEEV 125 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 +G D++V+RELT GIY+G+PR Sbjct: 126 VKGTDMIVIRELTSGIYYGEPR 147
>LEU3_THIDA (Q3SHL3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 353 Score = 139 bits (351), Expect = 4e-33 Identities = 71/142 (50%), Positives = 96/142 (67%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +LPGDGIGPE+++ A VL A S EG ++ + PLP+ TL AR Sbjct: 3 IAVLPGDGIGPEIISQAVKVLEALKS-EGAKIEMETAPIGGAGYDAAGDPLPEATLKLAR 61 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 +DA+LLGA+GG ++D ++ L+PE GLL IR L +FANLRPA + P+L AS+LK EV Sbjct: 62 EADAVLLGAVGGPQYDTLDRPLRPERGLLRIRKELNLFANLRPALLYPELASASSLKPEV 121 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 G+D+M+VRELTG +YFG+PR Sbjct: 122 VSGLDLMIVRELTGDVYFGQPR 143
>LEU3_CHRVO (Q7NUC2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 354 Score = 139 bits (349), Expect = 7e-33 Identities = 71/142 (50%), Positives = 96/142 (67%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +LPGDGIGPE++A A+ VL ++G+++ + VP P+ T AR Sbjct: 3 IAILPGDGIGPEIIAQAERVLEVL-RRDGLKIETEHAPLGGAAYDQYGVPYPEATQKLAR 61 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 +DA+LLGA+GG +D ++ L+PE GLL IR L +FANLRPA + P+L +ASTLK EV Sbjct: 62 EADAVLLGAVGGPAYDKLDRPLRPERGLLAIRKDLNLFANLRPAILYPELANASTLKPEV 121 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 G+DIM+VRELTG IYFG+PR Sbjct: 122 VAGLDIMIVRELTGDIYFGQPR 143
>LEU3_PELUB (Q4FP17) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 368 Score = 139 bits (349), Expect = 7e-33 Identities = 72/142 (50%), Positives = 88/142 (61%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I LLPGDGIGPEV+ K V+ S + ++ E P+ DE A Sbjct: 9 ILLLPGDGIGPEVIQEVKKVILWLNSNKSLDFEIDEDLAGGCSYDKHGTPITDEVFYKAL 68 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 S+ ++LGA+GG KWDN E KPE LL +R L +FANLRPA QLVDASTLK E+ Sbjct: 69 ESEFVMLGAVGGPKWDNLEFSKKPERALLKLRKELKLFANLRPAICFEQLVDASTLKPEI 128 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 G+DIM+VRELTGGIYFG+PR Sbjct: 129 VSGLDIMIVRELTGGIYFGEPR 150
>LEU3_THET8 (Q5SIY4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 345 Score = 138 bits (348), Expect = 9e-33 Identities = 68/142 (47%), Positives = 89/142 (62%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 + +LPGDGIGPEV A VL A EG+ L Y+ P P+ T Sbjct: 3 VAVLPGDGIGPEVTEAALKVLRALDEAEGLGLAYEVFPFGGAAIDAFGEPFPEPTRKGVE 62 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 ++A+LLG++GG KWD + ++PETGLL++R +FANLRPA V P L S LK E+ Sbjct: 63 EAEAVLLGSVGGPKWDGLPRKIRPETGLLSLRKSQDLFANLRPAKVFPGLERLSPLKEEI 122 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 A GVD+++VRELTGGIYFG+PR Sbjct: 123 ARGVDVLIVRELTGGIYFGEPR 144
>LEU3_THET2 (P61494) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 345 Score = 138 bits (348), Expect = 9e-33 Identities = 68/142 (47%), Positives = 89/142 (62%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 + +LPGDGIGPEV A VL A EG+ L Y+ P P+ T Sbjct: 3 VAVLPGDGIGPEVTEAALKVLRALDEAEGLGLAYEVFPFGGAAIDAFGEPFPEPTRKGVE 62 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 ++A+LLG++GG KWD + ++PETGLL++R +FANLRPA V P L S LK E+ Sbjct: 63 EAEAVLLGSVGGPKWDGLPRKIRPETGLLSLRKSQDLFANLRPAKVFPGLERLSPLKEEI 122 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 A GVD+++VRELTGGIYFG+PR Sbjct: 123 ARGVDVLIVRELTGGIYFGEPR 144
>LEU3_SILPO (Q5LWZ5) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 367 Score = 138 bits (347), Expect = 1e-32 Identities = 66/142 (46%), Positives = 94/142 (66%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 + +LPGDGIGPEV+A + ++ G K G+ E VPL DET+A A+ Sbjct: 6 LLILPGDGIGPEVMAEVRKIIGWFGDKRGLNFDVSEDLVGGAAYDVHGVPLADETMAKAQ 65 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 +DA+LLGA+GG K+D+ + +KPE GLL +R + +F+NLRPA L D S+LK+++ Sbjct: 66 EADAVLLGAVGGPKYDDLDFSVKPERGLLRLRKEMDLFSNLRPAQCFDALADFSSLKKDI 125 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 G+DIM+VRELT G+YFG+PR Sbjct: 126 VAGLDIMIVRELTSGVYFGEPR 147
>LEU3_THETH (P61495) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 345 Score = 137 bits (346), Expect = 2e-32 Identities = 68/142 (47%), Positives = 88/142 (61%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 + +LPGDGIGPEV A VL A EG+ L Y+ P P+ T Sbjct: 3 VAVLPGDGIGPEVTEAALKVLRALDEAEGLGLAYEVFPFGGAAIDAFGEPFPEPTRKGVE 62 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 ++A+LLG++GG KWD + + PETGLL++R +FANLRPA V P L S LK E+ Sbjct: 63 EAEAVLLGSVGGPKWDGLPRKISPETGLLSLRKSQDLFANLRPAKVFPGLERLSPLKEEI 122 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 A GVD+++VRELTGGIYFG+PR Sbjct: 123 ARGVDVLIVRELTGGIYFGEPR 144
>LEU3_THEAQ (P24098) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 344 Score = 137 bits (346), Expect = 2e-32 Identities = 68/142 (47%), Positives = 90/142 (63%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 + +LPGDGIGPEV A VL A +EG+ L Y+ P P+ T Sbjct: 3 VAVLPGDGIGPEVTEAALRVLKALDEREGLGLTYETFPFGGAAIDGYGEPFPEVTRKGVE 62 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 A++A+LLG++GG KWD + ++PE+GLL +R +FANLRPA V P L S LK E+ Sbjct: 63 AAEAVLLGSVGGPKWDALPRKIRPESGLLALRKSQDLFANLRPAKVFPGLERLSPLKEEI 122 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 A GVD+++VRELTGGIYFG+PR Sbjct: 123 ARGVDVLIVRELTGGIYFGEPR 144
>LEU3_THIFE (Q56268) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 358 Score = 137 bits (345), Expect = 2e-32 Identities = 70/142 (49%), Positives = 90/142 (63%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I + GDGIGPE+VA A+ VL A + LR E PLP +L A Sbjct: 4 IAIFAGDGIGPEIVAAARQVLDAVDQAAHLGLRCTEGLVGGAALDASDDPLPAASLQLAM 63 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 A+DA++LGA+GG +WD +PE GLL +R GL ++ANLRPA + PQL+DAS L+ E+ Sbjct: 64 AADAVILGAVGGPRWDAYPPAKRPEQGLLRLRKGLDLYANLRPAQIFPQLLDASPLRPEL 123 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 VDI+VVRELTG IYFG+PR Sbjct: 124 VRDVDILVVRELTGDIYFGQPR 145
>LEU31_DECAR (Q47HR1) 3-isopropylmalate dehydrogenase 1 (EC 1.1.1.85) (Beta-IPM| dehydrogenase 1) (IMDH 1) (3-IPM-DH 1) Length = 350 Score = 136 bits (343), Expect = 4e-32 Identities = 72/142 (50%), Positives = 93/142 (65%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +LPGDGIGPE+ A A VL++ K +E E P P+ T AR Sbjct: 3 ICVLPGDGIGPEITAQAVRVLNSLDLKFEME----EALLGGGAVDATGNPYPEATQKLAR 58 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 A+DA+LLGA+GG KWD+ + +PE GLL IR L +FANLRPA + P+L +ASTLK EV Sbjct: 59 AADAVLLGAVGGPKWDSLPREQRPERGLLGIRKDLNLFANLRPAILYPELANASTLKPEV 118 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 G+DI+++RELTG IYFG+PR Sbjct: 119 VAGLDILIIRELTGDIYFGQPR 140
>LEU3_DESVH (Q726X1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 357 Score = 136 bits (343), Expect = 4e-32 Identities = 70/142 (49%), Positives = 89/142 (62%), Gaps = 1/142 (0%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I LLPGDGIGPE+VA VL A + G + PLPD T+ A R Sbjct: 5 ICLLPGDGIGPEIVAQGTKVLDAVARRFGHTVSTSSALIGGAAIDATGSPLPDATVEACR 64 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 SDA+LLGA+GG KWD+ +PE GLL IR LG+FANLRPA + P+L A L+ ++ Sbjct: 65 TSDAVLLGAVGGPKWDDLPSEKRPEKGLLGIRKALGLFANLRPAALFPELAGACLLRADI 124 Query: 495 -AEGVDIMVVRELTGGIYFGKP 557 A G+D++VVRELTG +YFG+P Sbjct: 125 AAAGLDLVVVRELTGDVYFGQP 146
>LEU3_AZOSE (Q5P1J6) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 350 Score = 136 bits (342), Expect = 5e-32 Identities = 72/142 (50%), Positives = 91/142 (64%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +LPGDGIGPE+ A A V+ A K +E E P P+ T AR Sbjct: 3 ICILPGDGIGPEITAEAVRVIEALDLKFEME----EALLGGAAVDATGDPYPEATRKLAR 58 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 +DA+LLGA+GG KWD + +PE GLL IR LG+FANLRPA + P+L +AS+LK EV Sbjct: 59 EADAVLLGAVGGPKWDTLPREQRPERGLLGIRKDLGLFANLRPAILYPELANASSLKPEV 118 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 G+DI++VRELTG IYFG+PR Sbjct: 119 VAGLDILIVRELTGDIYFGQPR 140
>LEU3_THETN (Q8RDK0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 355 Score = 135 bits (341), Expect = 6e-32 Identities = 73/140 (52%), Positives = 88/140 (62%), Gaps = 1/140 (0%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +LPGDGIGPEV+ VL A K G+ K+ P P+ET Sbjct: 4 IAVLPGDGIGPEVIEEGLKVLKAVEEKYGLRFDIKKYPFGGEAIDKYGEPYPEETRNGCL 63 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 +SDA+LLGA+GG KWD E +PE GLL +R LGV+ANLRPA + P L DAS LK E+ Sbjct: 64 SSDAVLLGAVGGPKWDGLEGDKRPEAGLLALRKSLGVYANLRPAVLYPSLKDASPLKNEL 123 Query: 495 AE-GVDIMVVRELTGGIYFG 551 E G+DI+VVRELTGGIYFG Sbjct: 124 LEKGLDILVVRELTGGIYFG 143
>LEU3_NITWN (Q3SNU3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 370 Score = 134 bits (337), Expect = 2e-31 Identities = 66/142 (46%), Positives = 93/142 (65%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 + LLPGDGIGPEV+A K ++ ++ + +E V + D T+A A Sbjct: 6 LLLLPGDGIGPEVMAEVKRLVGWLDAQGIAKFETEEGLVGGASYDADKVSITDATMAKAL 65 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 A+DA+L GA+GG KWD+ ++PE GLL +R L ++ANLRPA P L ++S+LK EV Sbjct: 66 AADAVLFGAVGGPKWDSVPYEVRPEAGLLRLRKDLALYANLRPAICYPALAESSSLKPEV 125 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 EG+DIM+VRELTGG+YFG+P+ Sbjct: 126 VEGLDIMIVRELTGGVYFGEPK 147
>LEU3_RHOPA (Q6ND82) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 370 Score = 133 bits (335), Expect = 3e-31 Identities = 66/142 (46%), Positives = 88/142 (61%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 + LLPGDGIG EV+A ++ + V + D T+A A+ Sbjct: 6 LLLLPGDGIGTEVMAEVSRLIDWLNKAGIASFETEHGLVGGAAYDADKVAITDATMALAQ 65 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 ASDA++ GA+GG KWD +PE GLL +R LG+FANLRPA P L D+S+LKR+V Sbjct: 66 ASDAVIFGAVGGPKWDGVPYDARPEAGLLRLRKDLGLFANLRPAVCYPALADSSSLKRDV 125 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 EG+DIM+VRELTGG+YFG+P+ Sbjct: 126 VEGLDIMIVRELTGGVYFGEPK 147
>LEU3_CAUCR (Q9ABN3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 350 Score = 133 bits (334), Expect = 4e-31 Identities = 70/142 (49%), Positives = 88/142 (61%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 + LLPGDGIGPEV A + V +A +L+ E PL DE A Sbjct: 4 LLLLPGDGIGPEVCAQVRRVAAALTP----DLKVDEALYGGASYDTHGTPLTDEVREQAL 59 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 ASDA+L+GA+GG KW + +HL+PE GLLN+R + VFANLRPA L AS+LK E+ Sbjct: 60 ASDAVLMGAVGGPKWADAPRHLRPEAGLLNLRKAMDVFANLRPAYCFEALAGASSLKPEL 119 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 G+DIM VREL GG+YFG+PR Sbjct: 120 VSGLDIMFVRELVGGVYFGQPR 141
>LEU3_BRAJA (Q89X19) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 370 Score = 132 bits (333), Expect = 5e-31 Identities = 67/142 (47%), Positives = 88/142 (61%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 + LLPGDGIGPEV+ K ++ S + V + + +A A Sbjct: 6 LLLLPGDGIGPEVMGEVKRLIDWLNSAGIAKFETDTGLVGGSAYDAHKVSISEGDMAKAL 65 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 A+DAI+ GA+GG KWD ++PE GLL +R LG+FANLRPA P L DAS+LKRE Sbjct: 66 AADAIIFGAVGGPKWDAVPYEVRPEAGLLRLRKDLGLFANLRPAVCYPALADASSLKREA 125 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 EG+DIM+VRELTGG+YFG+P+ Sbjct: 126 VEGLDIMIVRELTGGVYFGEPK 147
>LEU32_DECAR (Q479H7) 3-isopropylmalate dehydrogenase 2 (EC 1.1.1.85) (Beta-IPM| dehydrogenase 2) (IMDH 2) (3-IPM-DH 2) Length = 358 Score = 132 bits (332), Expect = 7e-31 Identities = 70/142 (49%), Positives = 90/142 (63%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I ++PGDGIG E+ A A V+ A G+++ Y+ PLP ETL A Sbjct: 3 ICVIPGDGIGVEICAEAVRVIDALKDIHGLKIEYEYGLLGGAAYDQTGRPLPVETLRLAD 62 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 ++AILLGA+GG KWD +PE GLL IR LG+ ANLRP V P+L +ASTL+ EV Sbjct: 63 EANAILLGAVGGPKWDKLPAESRPERGLLGIRKYLGLNANLRPIKVYPELANASTLRPEV 122 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 G+D+M+VRELTG IYFG+PR Sbjct: 123 VSGLDMMIVRELTGDIYFGQPR 144
>LEU3_BURPS (Q63JL2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 355 Score = 132 bits (332), Expect = 7e-31 Identities = 71/142 (50%), Positives = 92/142 (64%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +LPGDGIGPE+V A VL+A K +E + PLPD TLA A+ Sbjct: 3 IAVLPGDGIGPEIVNEAVKVLNALDEKFELE----QAPVGGAGYEASGHPLPDATLALAK 58 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 +DAIL GA+G +K+D+ E+ L+PE +L +R L +FAN RPA PQLVDAS LK E+ Sbjct: 59 EADAILFGAVGDWKYDSLERALRPEQAILGLRKHLELFANFRPAICYPQLVDASPLKPEL 118 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 G+DI++VREL G IYFG+PR Sbjct: 119 VAGLDILIVRELNGDIYFGQPR 140
>LEU3_BURMA (Q62AI9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 355 Score = 132 bits (332), Expect = 7e-31 Identities = 71/142 (50%), Positives = 92/142 (64%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +LPGDGIGPE+V A VL+A K +E + PLPD TLA A+ Sbjct: 3 IAVLPGDGIGPEIVNEAVKVLNALDEKFELE----QAPVGGAGYEASGHPLPDATLALAK 58 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 +DAIL GA+G +K+D+ E+ L+PE +L +R L +FAN RPA PQLVDAS LK E+ Sbjct: 59 EADAILFGAVGDWKYDSLERALRPEQAILGLRKHLELFANFRPAICYPQLVDASPLKPEL 118 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 G+DI++VREL G IYFG+PR Sbjct: 119 VAGLDILIVRELNGDIYFGQPR 140
>LEU3_RHILO (Q98E57) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 367 Score = 132 bits (331), Expect = 9e-31 Identities = 66/140 (47%), Positives = 88/140 (62%) Frame = +3 Query: 141 LLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAARAS 320 LLPGDGIGPE +A K ++SA K G E + D +A A A+ Sbjct: 8 LLPGDGIGPEAMAEVKKLISAMNEKLGSGFATDEGLVGGCAYDAHGAAISDADMAKAMAA 67 Query: 321 DAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAE 500 DA+L GA+GG KWD ++PE GLL +R + +FANLRPA P L +S+LK+EV E Sbjct: 68 DAVLFGAVGGPKWDAVPYEVRPEAGLLRLRKDMELFANLRPAICYPALAASSSLKQEVVE 127 Query: 501 GVDIMVVRELTGGIYFGKPR 560 G+DI++VRELTGG+YFG+P+ Sbjct: 128 GLDILIVRELTGGVYFGEPK 147
>LEU3_CLOAB (Q97EE2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 357 Score = 131 bits (330), Expect = 1e-30 Identities = 68/141 (48%), Positives = 89/141 (63%), Gaps = 1/141 (0%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 + ++PGDGIG E+V A VL G+K + + E VPLP+ETL + Sbjct: 6 VAVIPGDGIGVEIVGEALKVLEKVGAKYDTKFNFTEVKAGGCAIDEFGVPLPNETLEICK 65 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 SDA+LLGA+GG KWD +PE L+ +R GLG++ANLRPA V L AS LK E+ Sbjct: 66 NSDAVLLGAVGGPKWDTLPGEKRPEKALMGLRGGLGLYANLRPAKVYDILKSASPLKEEI 125 Query: 495 A-EGVDIMVVRELTGGIYFGK 554 +GVD++VVRELTGGIYFG+ Sbjct: 126 INKGVDLLVVRELTGGIYFGE 146
>LEU3_BURCE (Q845W3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 355 Score = 130 bits (328), Expect = 2e-30 Identities = 70/142 (49%), Positives = 91/142 (64%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +LPGDGIGPE+V A VL+A K +E + PLPD TL A+ Sbjct: 3 IAVLPGDGIGPEIVTEAVKVLNALDEKFELE----QAPVGGAGYEARGHPLPDATLKLAK 58 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 +DAIL GA+G +K+D+ E+ L+PE +L +R L +FAN RPA PQLVDAS LK E+ Sbjct: 59 EADAILFGAVGDWKYDSLERALRPEQAILGLRKHLELFANFRPAICYPQLVDASPLKPEL 118 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 G+DI++VREL G IYFG+PR Sbjct: 119 VAGLDILIVRELNGDIYFGQPR 140
>LEU3_CANRU (Q9HDQ5) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 359 Score = 129 bits (324), Expect = 6e-30 Identities = 73/142 (51%), Positives = 89/142 (62%), Gaps = 2/142 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAG-SKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAA 311 I LLPGD +G EVVA A VL A + G + VPLPDE L AA Sbjct: 5 IVLLPGDHVGTEVVAEAVKVLKAIERTTPGTSFSFSTHLIGGAAIDATGVPLPDEALEAA 64 Query: 312 RASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLP-QLVDASTLKR 488 +ASDA+LLGA+GG KW + ++PE GLL IR LG++ANLRP + +LVD S LKR Sbjct: 65 KASDAVLLGAVGGPKWGTGD--VRPEQGLLKIRKELGLYANLRPCSFASSKLVDLSPLKR 122 Query: 489 EVAEGVDIMVVRELTGGIYFGK 554 E+ EG D +VVREL GGIYFG+ Sbjct: 123 EIVEGTDFVVVRELVGGIYFGE 144
>LEU3_PROMP (Q7V1R9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 357 Score = 129 bits (324), Expect = 6e-30 Identities = 64/142 (45%), Positives = 87/142 (61%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 + LL GDGIGPE+ ++ +L K G L KE P P ETL + Sbjct: 6 VVLLSGDGIGPEISEISITILKKLSKKYGFNLDIKEEYFGGIAYEKHNDPAPKETLDQCK 65 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 ASDA+LL +G K+D + L+PE+GLL +R L +FAN+RP + L+D+S+ K+EV Sbjct: 66 ASDAVLLACVGDVKYDTLPRELRPESGLLKLREALNLFANIRPVKIRKSLLDSSSFKKEV 125 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 E VD++VVREL GGIYFG+PR Sbjct: 126 IENVDLIVVRELIGGIYFGQPR 147
>LEU3_CLOPA (P31958) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 357 Score = 129 bits (323), Expect = 7e-30 Identities = 66/140 (47%), Positives = 87/140 (62%), Gaps = 1/140 (0%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I ++PGDGIGP++V A +++ G K + + E PLP ET+ + Sbjct: 6 IAVIPGDGIGPDIVREAVKIMTKVGEKYDTKFNFVEVKAGGDAIDAYGEPLPKETIDVCK 65 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 +S A+LLGA+GG KWDN E +PE LL +R LG++ANLRPA V L AS LK E+ Sbjct: 66 SSAAVLLGAVGGPKWDNLEGSKRPERALLGLRGALGLYANLRPAKVYNVLKSASPLKNEI 125 Query: 495 A-EGVDIMVVRELTGGIYFG 551 EGVD++VVREL GGIYFG Sbjct: 126 IDEGVDLLVVRELIGGIYFG 145
>LEU3_RHOBA (Q7UIE1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 359 Score = 127 bits (319), Expect = 2e-29 Identities = 66/140 (47%), Positives = 84/140 (60%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I LLPGDGIGPE+V A+ VL + G + PLP T+ A R Sbjct: 5 IVLLPGDGIGPEIVEQARLVLVKVAERFGHTFDFSSHQIGGIAIDETGDPLPQPTIDACR 64 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 + AILLGA+GG KWD+ +PE GLL IR LG+FANLRP + +L DAS L+ ++ Sbjct: 65 NAAAILLGAVGGPKWDDPSAKTRPEAGLLKIRKELGLFANLRPIKLFDELADASPLRADI 124 Query: 495 AEGVDIMVVRELTGGIYFGK 554 +G DI+ RELTGGIYFG+ Sbjct: 125 VKGTDILFFRELTGGIYFGE 144
>LEU3_NEILA (P50180) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) (Fragment) Length = 313 Score = 127 bits (318), Expect = 3e-29 Identities = 67/142 (47%), Positives = 92/142 (64%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +L GDGIGPE+VA VL ++G++ Y+ P P+ T R Sbjct: 5 IAILRGDGIGPEIVAETVRVLDKL-IEQGLDAGYEYAPLGGEAYDEYGHPYPEFTQNLCR 63 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 +DA+LLGA+G ++DN ++ L+PE GLL IR L +FANLRPA + P+L +ASTLK E+ Sbjct: 64 KADAVLLGAVGSPQYDNLDRPLRPERGLLAIRKDLNLFANLRPAVLYPELANASTLKPEI 123 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 G+DI++VRELTG IYFG+PR Sbjct: 124 VAGLDILIVRELTGDIYFGEPR 145
>LEU3_NEIMA (Q9JU79) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 356 Score = 127 bits (318), Expect = 3e-29 Identities = 67/142 (47%), Positives = 93/142 (65%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +L GDGIGPE+VA VL + +G+++ Y+ P P+ T R Sbjct: 5 IAILRGDGIGPEIVAETVRVLDKLIA-QGLDVGYEYAPLGGEAYDEYGHPYPEFTQNLCR 63 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 +DA+LLGA+G ++DN ++ L+PE GLL IR L +FANLRPA + P+L +ASTLK E+ Sbjct: 64 KADAVLLGAVGSPQYDNLDRPLRPERGLLAIRKDLNLFANLRPAILYPELANASTLKSEI 123 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 G+DI++VRELTG IYFG+PR Sbjct: 124 VAGLDILIVRELTGDIYFGEPR 145
>LEU3_LISIN (Q92A27) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 350 Score = 126 bits (317), Expect = 4e-29 Identities = 67/142 (47%), Positives = 86/142 (60%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 IT L GDGIGPE++A +L A +K + P+P ETL A + Sbjct: 5 ITSLAGDGIGPEIMASGIKILEAIAAKYNHTFEIESHPFGGAGIDAAGDPIPPETLKACQ 64 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 +DAILLGAIGG KWDN K +PE GLL +R LG+FAN+RP V + S LK+E+ Sbjct: 65 NADAILLGAIGGPKWDNAPK--RPEDGLLALRKALGLFANIRPIQVPSSITHLSPLKKEI 122 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 E D +VVRELTGG+YFG+P+ Sbjct: 123 VENTDFVVVRELTGGLYFGEPK 144
>LEU3_NITEU (Q82WI6) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 356 Score = 126 bits (317), Expect = 4e-29 Identities = 68/142 (47%), Positives = 91/142 (64%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I LL GDGIGPE++A A+ VL +EG+++ + P P+ T A Sbjct: 3 IALLAGDGIGPEIMAQAERVLRYF-QQEGLQIELEPGLLGGCAVDATGEPFPEATRQLAI 61 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 +DAILLGA+GG ++D + +PE GLL IR L +FANLRP + P+L +ASTLK EV Sbjct: 62 EADAILLGAVGGTQYDGLPREKRPEQGLLAIRKELNLFANLRPVVLYPELSNASTLKPEV 121 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 G+DI++VRELTG IYFG+PR Sbjct: 122 VAGLDILIVRELTGDIYFGRPR 143
>LEU3_BORPE (Q7VY73) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 358 Score = 126 bits (316), Expect = 5e-29 Identities = 64/142 (45%), Positives = 88/142 (61%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +LPGDGIGPE+V A+ VL A + L ++ PLP TL A+ Sbjct: 5 IAVLPGDGIGPEIVEQAERVLKALD----LPLELRQAPVGGAAFDQFEHPLPPATLELAQ 60 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 S A+L GA+G +K+D + +PE +L +R LG+FANLRPA + P+L AS+LK E+ Sbjct: 61 GSHAVLFGAVGDWKYDTLPREFRPEQAILGLRKALGLFANLRPAILYPELASASSLKPEI 120 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 G+DI+++RELTG IYFG PR Sbjct: 121 VSGLDILIIRELTGDIYFGTPR 142
>LEU3_BORPA (Q7W929) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 358 Score = 126 bits (316), Expect = 5e-29 Identities = 64/142 (45%), Positives = 88/142 (61%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +LPGDGIGPE+V A+ VL A + L ++ PLP TL A+ Sbjct: 5 IAVLPGDGIGPEIVEQAERVLKALD----LPLELRQAPVGGAAFDQFEHPLPPATLELAQ 60 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 S A+L GA+G +K+D + +PE +L +R LG+FANLRPA + P+L AS+LK E+ Sbjct: 61 GSHAVLFGAVGDWKYDTLPREFRPEQAILGLRKALGLFANLRPAILYPELASASSLKPEI 120 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 G+DI+++RELTG IYFG PR Sbjct: 121 VSGLDILIIRELTGDIYFGTPR 142
>LEU3_BORBR (Q7WKH4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 358 Score = 126 bits (316), Expect = 5e-29 Identities = 64/142 (45%), Positives = 88/142 (61%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +LPGDGIGPE+V A+ VL A + L ++ PLP TL A+ Sbjct: 5 IAVLPGDGIGPEIVEQAERVLKALD----LPLELRQAPVGGAAFDQFEHPLPPATLELAQ 60 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 S A+L GA+G +K+D + +PE +L +R LG+FANLRPA + P+L AS+LK E+ Sbjct: 61 GSHAVLFGAVGDWKYDTLPREFRPEQAILGLRKALGLFANLRPAILYPELASASSLKPEI 120 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 G+DI+++RELTG IYFG PR Sbjct: 121 VSGLDILIIRELTGDIYFGTPR 142
>LEU3_NEIMB (Q9JZI9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 356 Score = 126 bits (316), Expect = 5e-29 Identities = 67/142 (47%), Positives = 92/142 (64%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +L GDGIGPE+VA VL + +G++ Y+ P P+ T R Sbjct: 5 IAILRGDGIGPEIVAETVRVLDKLIA-QGLDAGYEYAPLGGEAYDEYGHPYPEFTQNLCR 63 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 +DA+LLGA+G ++DN ++ L+PE GLL IR L +FANLRPA + P+L +ASTLK E+ Sbjct: 64 KADAVLLGAVGSPQYDNLDRPLRPERGLLAIRKDLNLFANLRPAVLYPELANASTLKPEI 123 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 G+DI++VRELTG IYFG+PR Sbjct: 124 VAGLDILIVRELTGDIYFGEPR 145
>LEU3_LISMF (Q71Y34) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 350 Score = 125 bits (315), Expect = 6e-29 Identities = 67/142 (47%), Positives = 83/142 (58%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 IT L GDGIGPE++ VL A K + P+P TL A R Sbjct: 5 ITSLAGDGIGPEIMTSGLQVLEAVAKKYNHTFEIESHPFGGAGIDVAQDPIPSSTLKACR 64 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 +DAILLGAIGG KWDN K +PE GLL +R LG+FAN+RP V + S LK+E+ Sbjct: 65 DADAILLGAIGGPKWDNAPK--RPEDGLLALRKALGLFANIRPIQVPSSITHLSPLKKEI 122 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 E D +VVRELTGG+YFG+P+ Sbjct: 123 VENTDFVVVRELTGGLYFGEPK 144
>LEU3_NEIG1 (Q5F8T6) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 356 Score = 125 bits (315), Expect = 6e-29 Identities = 67/142 (47%), Positives = 92/142 (64%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +L GDGIGPE+VA VL + +G++ Y+ P P+ T R Sbjct: 5 IAILRGDGIGPEIVAETVRVLDKFIA-QGLDADYEYAPLGGEAYDEYGHPYPEFTQNLCR 63 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 +DA+LLGA+G ++DN ++ L+PE GLL IR L +FANLRPA + P+L +ASTLK E+ Sbjct: 64 KADAVLLGAVGSPQYDNLDRPLRPERGLLAIRKDLNLFANLRPAVLYPELANASTLKPEI 123 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 G+DI++VRELTG IYFG+PR Sbjct: 124 VAGLDILIVRELTGDIYFGEPR 145
>LEU3_SYMTH (Q67JY2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 368 Score = 125 bits (315), Expect = 6e-29 Identities = 69/143 (48%), Positives = 84/143 (58%), Gaps = 1/143 (0%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I LPGDGIGPEV A VL AA + G L + E P PDET A Sbjct: 8 IACLPGDGIGPEVTRGAVTVLQAAAAAYGFRLEFSEYLVGGAAYDAVGTPFPDETRDACD 67 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKRE- 491 +DAIL GA+GG +++ L+PE GLL IR ++ANLRP + P L DAS LK E Sbjct: 68 RADAILFGAVGGPRYEGLPWDLRPEAGLLAIRKRYDLYANLRPILLYPPLKDASPLKNEI 127 Query: 492 VAEGVDIMVVRELTGGIYFGKPR 560 + GVD ++VREL GGIYFG+PR Sbjct: 128 IGGGVDFIIVRELVGGIYFGEPR 150
>LEU3_DEHE1 (Q3Z896) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 365 Score = 125 bits (314), Expect = 8e-29 Identities = 63/142 (44%), Positives = 89/142 (62%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 +T+LPGDGIGPEV+A VL+A K Y+ V L ETLA + Sbjct: 5 LTVLPGDGIGPEVMAEGLKVLNAVAKKYKHSFEYQYGLIGGCCIDKEGVALSPETLAMCK 64 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 SDA+LL A+G ++D+ + + PE GLL +R GLG+FAN+RP V P LV+++ +K E+ Sbjct: 65 KSDAVLLAAVGDPRFDDPKLPVHPEDGLLALRRGLGLFANIRPVKVAPSLVNSAPIKAEI 124 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 +G D + +RELTGG+YF KP+ Sbjct: 125 VKGTDFIFIRELTGGVYFAKPK 146
>LEU3_RALEJ (Q46YW0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 355 Score = 125 bits (314), Expect = 8e-29 Identities = 67/142 (47%), Positives = 90/142 (63%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +LPGDGIGPE+VA A VL+A K +E PLP+ TL A+ Sbjct: 3 IAVLPGDGIGPEIVAEAVKVLNALDEKFEMET----APVGGAGYEAEGHPLPENTLKLAK 58 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 +DAIL GA+G +K+D+ E+ L+PE +L +R L +FAN RPA P+L AS+LK E+ Sbjct: 59 EADAILFGAVGDWKYDSLERALRPEQAILGLRKHLQLFANFRPAICYPELTGASSLKPEL 118 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 G+DI++VREL G IYFG+PR Sbjct: 119 VAGLDILIVRELNGDIYFGQPR 140
>LEU3_RHIME (Q92KY8) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 370 Score = 124 bits (312), Expect = 1e-28 Identities = 61/140 (43%), Positives = 87/140 (62%) Frame = +3 Query: 141 LLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAARAS 320 LLPGDGIGPE +A + +++ ++ E + + +A A A+ Sbjct: 8 LLPGDGIGPEAMAEVRKIIAYMNAERDAGFVTDEGLVGGSAYDAHGAAISEGDMAKALAA 67 Query: 321 DAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAE 500 DA+L GA+GG KWD ++PE GLL +R L +FANLRPA P L +AS+LK E+ E Sbjct: 68 DAVLFGAVGGPKWDAVPYEVRPEAGLLRLRKDLELFANLRPAICYPALANASSLKPELVE 127 Query: 501 GVDIMVVRELTGGIYFGKPR 560 G+DI++VRELTGG+YFG+P+ Sbjct: 128 GLDILIVRELTGGVYFGEPK 147
>LEU3_LISMO (Q8Y5R8) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 350 Score = 124 bits (311), Expect = 2e-28 Identities = 66/142 (46%), Positives = 83/142 (58%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 IT L GDGIGPE++ VL A K + P+P TL A + Sbjct: 5 ITSLAGDGIGPEIMTSGLQVLEAVAKKYNHTFEIESHPFGGAGIDVAQDPIPSSTLKACQ 64 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 +DAILLGAIGG KWDN K +PE GLL +R LG+FAN+RP V + S LK+E+ Sbjct: 65 DADAILLGAIGGPKWDNAPK--RPEDGLLALRKALGLFANIRPIQVPSSITHLSPLKKEI 122 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 E D +VVRELTGG+YFG+P+ Sbjct: 123 VENTDFVVVRELTGGLYFGEPK 144
>LEU3_AGRT5 (P24404) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 370 Score = 124 bits (311), Expect = 2e-28 Identities = 63/140 (45%), Positives = 82/140 (58%) Frame = +3 Query: 141 LLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAARAS 320 LLPGDGIGPE + + ++ S E V + D + A A+ Sbjct: 8 LLPGDGIGPEAMTEVRKLIEYMNSAHNAGFTVSEGLVGGSAYDAHGVAISDADMEKALAA 67 Query: 321 DAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAE 500 DAIL GA+GG KWD +PE GLL +R L +FANLRPA P L AS+LK E+ E Sbjct: 68 DAILFGAVGGPKWDGVPYEHRPEAGLLRLRKDLELFANLRPAICYPALAAASSLKPELVE 127 Query: 501 GVDIMVVRELTGGIYFGKPR 560 G+DI++VRELTGG+YFG+P+ Sbjct: 128 GLDILIVRELTGGVYFGEPK 147
>LEU3_PICAN (P34733) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 362 Score = 123 bits (309), Expect = 3e-28 Identities = 68/140 (48%), Positives = 85/140 (60%), Gaps = 1/140 (0%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I LLPGD +GPEVVA A VL A S GV+ + + VPL DE L AA+ Sbjct: 5 IVLLPGDHVGPEVVAEAVKVLEAVSSAIGVKFNFSKHLIGGASIDAYGVPLSDEALEAAK 64 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQ-LVDASTLKRE 491 +DA+LLGA+GG KW ++PE GLL IR L ++ANLRP + L+ S LK E Sbjct: 65 KADAVLLGAVGGPKWGTGS--VRPEQGLLKIRKELNLYANLRPCSFASDALLKLSPLKSE 122 Query: 492 VAEGVDIMVVRELTGGIYFG 551 + +G D +VVREL GGIYFG Sbjct: 123 IVKGTDFVVVRELVGGIYFG 142
>LEU3_PELCD (Q3A3B2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 365 Score = 122 bits (307), Expect = 5e-28 Identities = 70/144 (48%), Positives = 86/144 (59%), Gaps = 2/144 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 + +LPGDGIGPE++A A VL A K V + LPD T+ + Sbjct: 7 LAVLPGDGIGPEIMAEAMKVLDAVEQKFQVRFERQFANVGGAAIDRDGKALPDATVEICQ 66 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETG-LLNIRAGLGVFANLRPATVLPQLVDASTLKRE 491 ASDAIL G++GG KWD +PE G LL +R G+F NLRPA V P L AS+LK E Sbjct: 67 ASDAILFGSVGGPKWDTLPAEERPERGALLPLRRIFGLFCNLRPAIVFPALTSASSLKEE 126 Query: 492 V-AEGVDIMVVRELTGGIYFGKPR 560 V A G DI+VVRELTGGIYF +P+ Sbjct: 127 VIAGGFDILVVRELTGGIYFAQPK 150
>LEU3_BRUSU (Q8FVF3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 370 Score = 122 bits (307), Expect = 5e-28 Identities = 60/142 (42%), Positives = 88/142 (61%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 + LLPGDGIGPE +A + V++ S + +E + D + A Sbjct: 6 LLLLPGDGIGPEAMAEVRKVIAFLNSDLNLGFETEEGLVGGCAYDAHGQAISDADMEKAL 65 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 A+DA+L GA+GG KWD+ ++PE GLL +R + ++ANLRPA P L +S+LK EV Sbjct: 66 AADAVLFGAVGGPKWDSVPYEVRPEAGLLRLRKDMQLYANLRPAICYPALAHSSSLKPEV 125 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 EG+DI+++RELTGG+YFG+P+ Sbjct: 126 IEGLDILILRELTGGVYFGEPK 147
>LEU3_ZYMMO (Q5NPQ9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 349 Score = 122 bits (305), Expect = 9e-28 Identities = 64/142 (45%), Positives = 85/142 (59%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I LL GDGIGPE+ A A +L A G E+ + E PLP+ETL + Sbjct: 3 IALLAGDGIGPEITAEAVKILKAV---VGQEIEFDEALIGGAAWKVTGSPLPEETLKLCK 59 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 SDAIL G++G + D+ E+ L+PE +L +R L +FANLRPA + P+L S LK + Sbjct: 60 NSDAILFGSVGDPECDHLERALRPEQAILGLRKELDLFANLRPARLFPELQAESPLKENI 119 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 G D+M+VRELTG +YFG PR Sbjct: 120 VTGTDLMIVRELTGDVYFGTPR 141
>LEU3_BRUME (Q8YCX4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 370 Score = 122 bits (305), Expect = 9e-28 Identities = 60/142 (42%), Positives = 88/142 (61%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 + LLPGDGIGPE +A + V++ S + +E + D + A Sbjct: 6 LLLLPGDGIGPEAMAEVRKVIAFLNSDLNLGFETEEGLVGGCAYDAHGQAISDADMEKAL 65 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 A+DA+L GA+GG KWD+ ++PE GLL +R + ++ANLRPA P L +S+LK EV Sbjct: 66 AADAVLFGAVGGPKWDSVPYEVRPEGGLLRLRKDMQLYANLRPAICYPALAHSSSLKPEV 125 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 EG+DI+++RELTGG+YFG+P+ Sbjct: 126 IEGLDILILRELTGGVYFGEPK 147
>LEU3_RALSO (Q8XXX5) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 356 Score = 121 bits (304), Expect = 1e-27 Identities = 64/142 (45%), Positives = 87/142 (61%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +LPGDGIG E+VA A VL G +E PLP++TL A+ Sbjct: 4 IAVLPGDGIGTEIVAEAVKVLKTLGETFEMET----APVGGAGYEAKGHPLPEDTLKLAK 59 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 +DAIL GA+G +K+D + L+PE +L +R L +FAN RPA P+L AS++K E+ Sbjct: 60 EADAILFGAVGDWKYDTLPRELRPEQAILGLRKHLQLFANFRPAICYPELAGASSMKPEI 119 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 G+DI++VRELTG IYFG+PR Sbjct: 120 VAGLDILIVRELTGDIYFGQPR 141
>LEU3_HELHP (Q7VH33) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 357 Score = 121 bits (303), Expect = 2e-27 Identities = 63/141 (44%), Positives = 86/141 (60%), Gaps = 1/141 (0%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I ++ GDGIG EV+ A +L A K ++E LP ++L + Sbjct: 5 IAVIYGDGIGKEVITQALKILKAVAKKYEHTFIFEEVLAGGAAIDECGECLPMKSLQICK 64 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 SD++LLGA+GG KWDN H +PE LL +R LG+FAN+RPAT+LPQL AS LK E+ Sbjct: 65 QSDSVLLGAVGGPKWDNEPSHNRPEKALLTLRKELGLFANIRPATLLPQLSKASPLKDEI 124 Query: 495 A-EGVDIMVVRELTGGIYFGK 554 G+D ++VREL GG+YFG+ Sbjct: 125 LNRGIDFIIVRELIGGVYFGE 145
>LEU3_BACCZ (Q63DX7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 354 Score = 120 bits (302), Expect = 2e-27 Identities = 67/142 (47%), Positives = 86/142 (60%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I L GDG+GPEV+ AK+VL G ++ PLP TLAA Sbjct: 5 IVCLAGDGVGPEVMESAKEVLHMVERLYGHHFHLQDEHFGGVAIDLTGQPLPQRTLAACL 64 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 ASDA+LLGA+GG +WD ++ +PE GLL +R GLGVFAN+RP TV + S LK+ Sbjct: 65 ASDAVLLGAVGGPRWDGAKE--RPEKGLLALRKGLGVFANVRPVTVESETAHLSPLKK-- 120 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 A+ +D +VVRELTGGIYF P+ Sbjct: 121 ADEIDFVVVRELTGGIYFSYPK 142
>LEU3_BACC1 (Q73B99) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 354 Score = 120 bits (300), Expect = 3e-27 Identities = 67/142 (47%), Positives = 86/142 (60%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I L GDG+GPEV+ AK+VL G ++ PLP TLAA Sbjct: 5 IVCLAGDGVGPEVMESAKEVLHMVERLYGHHFHLQDEYFGGSAIDLNGQPLPQRTLAACL 64 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 ASDA+LLGA+GG +WD+ ++ +PE GLL +R GLGVFAN+RP TV S LK+ Sbjct: 65 ASDAVLLGAVGGPRWDSAKE--RPEKGLLALRKGLGVFANVRPVTVESATAHLSPLKK-- 120 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 A+ +D +VVRELTGGIYF P+ Sbjct: 121 ADEIDFVVVRELTGGIYFSYPK 142
>LEU3_BACAN (Q81T67) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 354 Score = 119 bits (299), Expect = 4e-27 Identities = 67/142 (47%), Positives = 85/142 (59%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I L GDG+GPEV+ AK+VL G ++ PLP TLAA Sbjct: 5 IVCLAGDGVGPEVMESAKEVLHMVERLYGHHFHLQDEHFGGVAIDLTGQPLPQRTLAACL 64 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 ASDA+LLGA+GG +WD ++ +PE GLL +R GLGVFAN+RP TV S LK+ Sbjct: 65 ASDAVLLGAVGGPRWDGAKE--RPEKGLLALRKGLGVFANVRPVTVESATAHLSPLKK-- 120 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 A+ +D +VVRELTGGIYF P+ Sbjct: 121 ADEIDFVVVRELTGGIYFSYPK 142
>LEU3_BACCR (Q81G11) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 354 Score = 119 bits (298), Expect = 6e-27 Identities = 67/142 (47%), Positives = 85/142 (59%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I L GDG+GPEV+ AK+VL G ++ PLP TLAA Sbjct: 5 IVCLAGDGVGPEVMESAKEVLHMVERLYGHHFHLQDEYFGGVAIDLTGQPLPQRTLAACL 64 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 ASDA+LLGA+GG +WD+ ++ +PE GLL +R GLGVFAN+RP TV S LK Sbjct: 65 ASDAVLLGAVGGPRWDSAKE--RPEKGLLALRKGLGVFANVRPVTVESATAHLSPLKN-- 120 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 A+ +D +VVRELTGGIYF P+ Sbjct: 121 ADEIDFVVVRELTGGIYFSYPK 142
>LEU3_DEHSC (Q3ZXI7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 365 Score = 119 bits (298), Expect = 6e-27 Identities = 60/142 (42%), Positives = 87/142 (61%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 +T+LPGDGIGPEV+ VL+A K +Y+ V L LA + Sbjct: 5 LTVLPGDGIGPEVMDEGLKVLNAVAKKYKHTFKYQYGLIGGCCIDKEGVALSPAALAMCK 64 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 SDA+LL A+G ++D+ + + PE GLL +R GLG+FAN+RP V P LV+++ +K E+ Sbjct: 65 KSDAVLLAAVGDPRFDDPKLPVHPEDGLLALRKGLGLFANIRPVKVAPSLVNSTPIKAEI 124 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 +G D + +RELTGG+YF KP+ Sbjct: 125 VKGTDFIFIRELTGGVYFAKPK 146
>LEU3_YAMOH (P41926) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 368 Score = 118 bits (296), Expect = 1e-26 Identities = 65/141 (46%), Positives = 85/141 (60%), Gaps = 1/141 (0%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 IT++PGD +G E+ A VL A V+ +K VPLPDETL AA+ Sbjct: 6 ITVVPGDHVGTEICDEAIKVLKAIEKVSPVKFEFKHHLIGGAAIDATGVPLPDETLEAAK 65 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPAT-VLPQLVDASTLKRE 491 +SDA+LLGA+GG KW ++PE GLL IR L ++ANLRP V L++ S LK E Sbjct: 66 SSDAVLLGAVGGPKWGTGA--VRPEQGLLKIRKELNLYANLRPCNFVSDSLLELSPLKSE 123 Query: 492 VAEGVDIMVVRELTGGIYFGK 554 + +G + VVREL GGIYFG+ Sbjct: 124 IVKGTNFTVVRELVGGIYFGE 144
>LEU3_BACHK (Q6HLF2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 354 Score = 118 bits (296), Expect = 1e-26 Identities = 67/142 (47%), Positives = 84/142 (59%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I L GDG+GPEV+ AK VL G ++ PLP TLAA Sbjct: 5 IVCLAGDGVGPEVMESAKGVLHMVERLYGHHFHLQDEHFGGVAIDLTGQPLPQRTLAACL 64 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 ASDA+LLGA+GG +WD ++ +PE GLL +R GLGVFAN+RP TV S LK+ Sbjct: 65 ASDAVLLGAVGGPRWDGAKE--RPEKGLLALRKGLGVFANVRPVTVESATAHLSPLKK-- 120 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 A+ +D +VVRELTGGIYF P+ Sbjct: 121 ADEIDFVVVRELTGGIYFSYPK 142
>LEU3_CANBO (Q01987) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 365 Score = 118 bits (295), Expect = 1e-26 Identities = 65/141 (46%), Positives = 85/141 (60%), Gaps = 2/141 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGS-KEGVELRYKEXXXXXXXXXXXXVPLPDETLAAA 311 I LLPGD +G EVV A +L + K ++ +++ VPLPDE L AA Sbjct: 8 IVLLPGDHVGVEVVEEAVKILKSISEVKPEIQFKFENHLIGGAAIDATGVPLPDEALEAA 67 Query: 312 RASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPAT-VLPQLVDASTLKR 488 + SDA+LLGA+GG KW E ++PE GLL IR L ++ANLRP +L+D S LK Sbjct: 68 KKSDAVLLGAVGGPKWGTGE--VRPEQGLLKIRKELNLYANLRPCNFASDKLLDLSPLKS 125 Query: 489 EVAEGVDIMVVRELTGGIYFG 551 ++ +G D VVREL GGIYFG Sbjct: 126 DIVKGTDFTVVRELVGGIYFG 146
>LEU3_GLUOX (Q5FUG5) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 369 Score = 118 bits (295), Expect = 1e-26 Identities = 59/142 (41%), Positives = 83/142 (58%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 + +L GDGIGPEV+ ++ + G++L E VP+ DE + AR Sbjct: 7 LLVLAGDGIGPEVMREVARIVHWMSAHRGLKLEITEELVGAASLAVHGVPIRDEVIELAR 66 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 SDA+L G++G W + +PE +L +R L +FANLRPA + L+DAS LK EV Sbjct: 67 QSDAVLFGSVGDPAWSHVGFDKRPEVAILKLRKELELFANLRPAKLFDALIDASALKPEV 126 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 G+D+M+VRE GGIYFG+PR Sbjct: 127 VRGLDLMIVRETVGGIYFGEPR 148
>LEU3_STAAS (Q6G7Q0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 348 Score = 117 bits (293), Expect = 2e-26 Identities = 62/142 (43%), Positives = 84/142 (59%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I LPGDGIGPE++ + +L +K + + PL ++TL A + Sbjct: 5 IVALPGDGIGPEILNGSLSLLEIISNKYNFNYQIEHHEFGGASIDTFGEPLTEKTLNACK 64 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 +DAILLGAIGG KW + + +PE GLL +R L +FAN+RP TV+ S LK E Sbjct: 65 RADAILLGAIGGPKW--TDPNNRPEQGLLKLRKSLNLFANIRPTTVVKGASSLSPLKEER 122 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 EG D+++VRELT GIYFG+PR Sbjct: 123 VEGTDLVIVRELTSGIYFGEPR 144
>LEU3_STAAN (P65101) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 348 Score = 117 bits (293), Expect = 2e-26 Identities = 62/142 (43%), Positives = 84/142 (59%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I LPGDGIGPE++ + +L +K + + PL ++TL A + Sbjct: 5 IVALPGDGIGPEILNGSLSLLEIISNKYNFNYQIEHHEFGGASIDTFGEPLTEKTLNACK 64 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 +DAILLGAIGG KW + + +PE GLL +R L +FAN+RP TV+ S LK E Sbjct: 65 RADAILLGAIGGPKW--TDPNNRPEQGLLKLRKSLNLFANIRPTTVVKGASSLSPLKEER 122 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 EG D+++VRELT GIYFG+PR Sbjct: 123 VEGTDLVIVRELTSGIYFGEPR 144
>LEU3_STAAM (P65100) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 348 Score = 117 bits (293), Expect = 2e-26 Identities = 62/142 (43%), Positives = 84/142 (59%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I LPGDGIGPE++ + +L +K + + PL ++TL A + Sbjct: 5 IVALPGDGIGPEILNGSLSLLEIISNKYNFNYQIEHHEFGGASIDTFGEPLTEKTLNACK 64 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 +DAILLGAIGG KW + + +PE GLL +R L +FAN+RP TV+ S LK E Sbjct: 65 RADAILLGAIGGPKW--TDPNNRPEQGLLKLRKSLNLFANIRPTTVVKGASSLSPLKEER 122 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 EG D+++VRELT GIYFG+PR Sbjct: 123 VEGTDLVIVRELTSGIYFGEPR 144
>LEU3_SCHPO (P18869) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 371 Score = 117 bits (293), Expect = 2e-26 Identities = 66/142 (46%), Positives = 86/142 (60%), Gaps = 2/142 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEG-VELRYKEXXXXXXXXXXXXVPLPDETLAAA 311 I +LPGD IGPE+VA A +VL K ++L ++E PL DET+ A Sbjct: 6 IVVLPGDHIGPEIVASALEVLKVVEKKRPELKLEFEEHKIGGASIDAYGTPLTDETVKAC 65 Query: 312 RASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQ-LVDASTLKR 488 +D +LLGA+GG +W N + +PE GLL +R +GV+ANLRP + LV S LK Sbjct: 66 LEADGVLLGAVGGPEWTN--PNCRPEQGLLKLRKSMGVWANLRPCNFASKSLVKYSPLKP 123 Query: 489 EVAEGVDIMVVRELTGGIYFGK 554 E+ EGVD VVRELTGG YFG+ Sbjct: 124 EIVEGVDFCVVRELTGGCYFGE 145
>LEU3_VIBCH (Q9KP82) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 117 bits (293), Expect = 2e-26 Identities = 65/144 (45%), Positives = 87/144 (60%), Gaps = 2/144 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +LPGDGIGPEV+A A VL A K G+ +E PLP+ TL A Sbjct: 8 IAVLPGDGIGPEVMAQAHKVLDAIEQKHGIRFSREEHDVGGIAIDNHGCPLPESTLRACE 67 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETG-LLNIRAGLGVFANLRPATVLPQLVDASTLKRE 491 +DA+L G++GG KW++ + +PE G LL +R +F NLRPA + L S L+ + Sbjct: 68 EADAVLFGSVGGPKWEHLPPNEQPERGALLPLRKHFQLFCNLRPAQIHQGLEAFSPLRAD 127 Query: 492 V-AEGVDIMVVRELTGGIYFGKPR 560 + A G DI+VVRELTGGIYFG+P+ Sbjct: 128 ISARGFDIVVVRELTGGIYFGQPK 151
>LEU3_STAAR (Q6GF15) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 348 Score = 117 bits (292), Expect = 3e-26 Identities = 62/142 (43%), Positives = 84/142 (59%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I LPGDGIGPE++ + +L +K + + PL ++TL A + Sbjct: 5 IVALPGDGIGPEILNGSLSLLEIISNKYNFNYQIEHHEFGGASIDTFGEPLTEKTLNACK 64 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 +DAILLGAIGG KW + + +PE GLL +R L +FAN+RP TV+ S LK E Sbjct: 65 RADAILLGAIGGPKW--TDPNNRPEQGLLKLRKSLNLFANIRPTTVVKGASSLSPLKAER 122 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 EG D+++VRELT GIYFG+PR Sbjct: 123 VEGTDLVIVRELTSGIYFGEPR 144
>LEU3_SHEON (Q8E9N3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 364 Score = 117 bits (292), Expect = 3e-26 Identities = 64/144 (44%), Positives = 87/144 (60%), Gaps = 2/144 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +L GDGIGPEV+A A+ VL A ++ G+ + Y E PLP+ TL Sbjct: 5 IAVLAGDGIGPEVMAEARKVLKAVEARFGLNIEYTEYDVGGIAIDNHGCPLPEATLKGCE 64 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETG-LLNIRAGLGVFANLRPATVLPQLVDASTLKRE 491 A+DAIL G++GG KW+ + +PE G LL +R +F NLRPA + L S L+ + Sbjct: 65 AADAILFGSVGGPKWEKLPPNEQPERGALLPLRGHFELFCNLRPAKLHDGLEHMSPLRSD 124 Query: 492 V-AEGVDIMVVRELTGGIYFGKPR 560 + A G D++ VRELTGGIYFGKP+ Sbjct: 125 ISARGFDVLCVRELTGGIYFGKPK 148
>LEU3_PSEHT (Q3IJS3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 358 Score = 117 bits (292), Expect = 3e-26 Identities = 64/142 (45%), Positives = 86/142 (60%), Gaps = 2/142 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 + +L GDGIGPE++A A+ VL A +K G L + LP T+ A Sbjct: 8 VAVLAGDGIGPEIMAAAEQVLDAVSNKFGFTLNREHHAIGGAAIDKHGKALPQSTVTACE 67 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETG-LLNIRAGLGVFANLRPATVLPQLVDASTLKRE 491 +DAIL GA+GG KW++ +PE G LL +R G+F NLRPA +LP L AS L+ + Sbjct: 68 NADAILFGAVGGPKWEHLPPDEQPERGSLLPLRKHFGLFCNLRPAQLLPALSTASPLRAD 127 Query: 492 VAE-GVDIMVVRELTGGIYFGK 554 ++E G DI+ VRELTGGIYFG+ Sbjct: 128 ISEQGFDILCVRELTGGIYFGE 149
>LEU3_GEOSL (Q748X2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 362 Score = 117 bits (292), Expect = 3e-26 Identities = 64/144 (44%), Positives = 89/144 (61%), Gaps = 2/144 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 + +LPGDGIGPEV+A A VL A +K V+ LP+ T+ + Sbjct: 7 VAVLPGDGIGPEVMAEALRVLDAVEAKYDVKFERTHANVGGAGIDIEGKALPETTVNICK 66 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETG-LLNIRAGLGVFANLRPATVLPQLVDASTLKRE 491 A+DAIL G++GG KW++ +PE G LL +R G++ANLRPA + P L AS+LK E Sbjct: 67 AADAILFGSVGGPKWESLPPDEQPERGALLPLRKIFGLYANLRPAIIFPSLTGASSLKEE 126 Query: 492 V-AEGVDIMVVRELTGGIYFGKPR 560 V A G +++V+RELTGGIYF +P+ Sbjct: 127 VIAGGFNVLVIRELTGGIYFAQPK 150
>LEU3_STAAW (Q8NVJ0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 348 Score = 116 bits (291), Expect = 4e-26 Identities = 62/142 (43%), Positives = 84/142 (59%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I LPGDGIGPE++ + +L +K + + PL ++TL A + Sbjct: 5 IVALPGDGIGPEILNGSLSLLEIISNKYNFNYQIEHHEFGGASIDTFGEPLTEKTLNACK 64 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 +DAILLGAIGG KW + + +PE GLL +R L +FAN+RP TV+ S LK E Sbjct: 65 RADAILLGAIGGPKW--TDPNNRPEQGLLKLRKSLNLFANIRPTTVVKGASSLSPLKEER 122 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 EG D+++VRELT GIYFG+PR Sbjct: 123 VEGKDLVIVRELTSGIYFGEPR 144
>LEU3_LEPIN (P24015) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 358 Score = 116 bits (291), Expect = 4e-26 Identities = 62/144 (43%), Positives = 88/144 (61%), Gaps = 2/144 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 + +L GDGIGPEV+ +A VL A + E ++KE PLP ETL Sbjct: 4 VAVLSGDGIGPEVMEIAISVLKKALGAKVSEFQFKEGFVGGIAIDKTGHPLPPETLKLCE 63 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETG-LLNIRAGLGVFANLRPATVLPQLVDASTLKRE 491 S AIL G++GG KW+ +PE G LL +R +FANLRPA + P+L +AS ++ + Sbjct: 64 ESSAILFGSVGGPKWETLPPEKQPERGALLPLRKHFDLFANLRPAIIYPELKNASPVRSD 123 Query: 492 -VAEGVDIMVVRELTGGIYFGKPR 560 + G+DI+++RELTGGIYFG+P+ Sbjct: 124 IIGNGLDILILRELTGGIYFGQPK 147
>LEU3_LEPIC (Q72RH7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 358 Score = 116 bits (291), Expect = 4e-26 Identities = 62/144 (43%), Positives = 88/144 (61%), Gaps = 2/144 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 + +L GDGIGPEV+ +A VL A + E ++KE PLP ETL Sbjct: 4 VAVLSGDGIGPEVMEIAISVLKKALGAKVSEFQFKEGFVGGIAIDKTGHPLPPETLKLCE 63 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETG-LLNIRAGLGVFANLRPATVLPQLVDASTLKRE 491 S AIL G++GG KW+ +PE G LL +R +FANLRPA + P+L +AS ++ + Sbjct: 64 ESSAILFGSVGGPKWETLPPEKQPERGALLPLRKHFDLFANLRPAIIYPELKNASPVRSD 123 Query: 492 -VAEGVDIMVVRELTGGIYFGKPR 560 + G+DI+++RELTGGIYFG+P+ Sbjct: 124 IIGNGLDILILRELTGGIYFGQPK 147
>LEU3_VIBPA (Q87SS8) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 116 bits (291), Expect = 4e-26 Identities = 64/144 (44%), Positives = 87/144 (60%), Gaps = 2/144 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +LPGDGIGPEV+A A VL A K G+ +E PLP+ T+ A Sbjct: 8 IAVLPGDGIGPEVMAQAHKVLDAIEQKHGISFEREEHDVGGIAIDNHGCPLPESTVTACE 67 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETG-LLNIRAGLGVFANLRPATVLPQLVDASTLKRE 491 SDA+L G++GG KW++ + +PE G LL +R +F NLRPA + L S L+ + Sbjct: 68 ESDAVLFGSVGGPKWEHLPPNDQPERGALLPLRKHFQLFCNLRPAQIHAGLEAFSPLRAD 127 Query: 492 VA-EGVDIMVVRELTGGIYFGKPR 560 ++ G DI+VVRELTGGIYFG+P+ Sbjct: 128 ISGRGFDIVVVRELTGGIYFGQPK 151
>LEU3_STAAC (Q5HEE3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 348 Score = 115 bits (289), Expect = 6e-26 Identities = 61/142 (42%), Positives = 83/142 (58%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I LPGDGIGPE++ + +L +K + + PL ++TL A + Sbjct: 5 IVALPGDGIGPEILNGSLSLLEIISNKYNFNYQIEHHEFGGASIDTFGEPLTEKTLNACK 64 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 +DAILLGAIGG KW + + +PE GLL +R L +F N+RP TV+ S LK E Sbjct: 65 RADAILLGAIGGPKW--TDPNNRPEQGLLKLRKSLNLFVNIRPTTVVKGASSLSPLKEER 122 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 EG D+++VRELT GIYFG+PR Sbjct: 123 VEGTDLVIVRELTSGIYFGEPR 144
>LEU3_DEIRA (Q9RTH9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 352 Score = 115 bits (289), Expect = 6e-26 Identities = 66/145 (45%), Positives = 81/145 (55%), Gaps = 3/145 (2%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 + LPGDGIGPEV A A VL VE E P P T A + Sbjct: 4 VITLPGDGIGPEVTAAAVQVLREVAPDVTVE----EHAIGGGAYDAHGEPFPTSTRDALK 59 Query: 315 ASDAILLGAIGGYK---WDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLK 485 +DA+LLG +GG W+ +HL+PE+GLL +R LG +ANLRP V P L S LK Sbjct: 60 EADAVLLGTVGGAHDSAWNQLPRHLRPESGLLALRKALGCYANLRPVRVQPGLEHLSPLK 119 Query: 486 REVAEGVDIMVVRELTGGIYFGKPR 560 E+A GVDI++VREL GGIYF + R Sbjct: 120 AELARGVDILIVRELLGGIYFDQDR 144
>LEU3_STAS1 (Q49Z13) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 346 Score = 115 bits (289), Expect = 6e-26 Identities = 62/142 (43%), Positives = 82/142 (57%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I LPGDGIGPE++ + ++L + E + PLPD TL A + Sbjct: 5 IVALPGDGIGPEILNGSLEILQQLSKEFHFEYELESHDFGGIAIDNHGKPLPDSTLNACK 64 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 +DAILLGA+GG KW + + +PE GLL IR LG+FAN+RP TV S +K E Sbjct: 65 NADAILLGAVGGPKW--TDPNNRPEQGLLGIRKALGLFANIRPTTVTNGTSHLSPIKEER 122 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 D ++VRELTGGIYFG+P+ Sbjct: 123 VANTDFILVRELTGGIYFGEPK 144
>LEU3_COLP3 (Q47WG3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 362 Score = 115 bits (289), Expect = 6e-26 Identities = 63/144 (43%), Positives = 87/144 (60%), Gaps = 2/144 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +L GDGIGPEV+ AK VL+ SK E+ ++ LPD T+A Sbjct: 4 IAILAGDGIGPEVMVEAKKVLNTVASKFDFEITTQDYDIGGAAIDNHGNALPDSTMAGCI 63 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPE-TGLLNIRAGLGVFANLRPATVLPQLVDASTLKRE 491 SDAIL G++GG KW N +PE LL +R+ +F N+RPAT+ P L STL+ + Sbjct: 64 ESDAILFGSVGGPKWANLPPTEQPERCALLGLRSHFDLFCNMRPATLQPALSSLSTLRSD 123 Query: 492 VAE-GVDIMVVRELTGGIYFGKPR 560 ++E G D++V+RELTG IYFG+P+ Sbjct: 124 ISEQGFDVLVIRELTGDIYFGEPK 147
>LEU3_PHACH (O59930) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 380 Score = 115 bits (287), Expect = 1e-25 Identities = 69/142 (48%), Positives = 86/142 (60%), Gaps = 2/142 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSA-AGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAA 311 I +LPGDGIGPEVVA A VL + S VE++ + PL TL A Sbjct: 8 IVILPGDGIGPEVVAEATRVLEVVSASSSDVEIKLETHDFGGCSIDKHGEPLTAATLEAC 67 Query: 312 RASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQ-LVDASTLKR 488 + +DAILLGAIGG KW N K ++PE LL +R LG++AN+RPA L+ S LK Sbjct: 68 KLADAILLGAIGGPKWGVNSK-VRPEQALLALRKALGLYANIRPANFASDSLLAYSPLKP 126 Query: 489 EVAEGVDIMVVRELTGGIYFGK 554 VA GVDI+V+REL GG YFG+ Sbjct: 127 SVARGVDIIVIRELIGGAYFGE 148
>LEU3_CANMI (Q6PY58) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 115 bits (287), Expect = 1e-25 Identities = 64/142 (45%), Positives = 83/142 (58%), Gaps = 2/142 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKE-GVELRYKEXXXXXXXXXXXXVPLPDETLAAA 311 I +LPGD +G E+ A VL+A K ++ ++ VPLPDE L A+ Sbjct: 7 IVVLPGDHVGTEITEEATKVLNAIAEKRPNIKFDFQHHLIGGAAIDATGVPLPDEALEAS 66 Query: 312 RASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPAT-VLPQLVDASTLKR 488 + +DA+LLGA+GG KW + ++PE GLL IR LG++ANLRP L+D S LK Sbjct: 67 KKADAVLLGAVGGPKWGTGD--VRPEQGLLKIRKELGLYANLRPCNFAFDSLLDMSPLKP 124 Query: 489 EVAEGVDIMVVRELTGGIYFGK 554 E A G D VVREL GIYFGK Sbjct: 125 EYARGTDFTVVRELVCGIYFGK 146
>LEU3_STAES (Q8CNL2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 347 Score = 114 bits (286), Expect = 1e-25 Identities = 60/141 (42%), Positives = 83/141 (58%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I LPGDGIGPE+++ ++L K E + PL +ETL + + Sbjct: 5 IVALPGDGIGPEILSGTLELLKLISEKYHFEYHLESHHFGGVSIDYYGTPLTNETLQSCK 64 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 +DAILLGAIGG KW + + +PE GLL +R L +FAN+RP V S LK+++ Sbjct: 65 NADAILLGAIGGPKW--TDPNNRPEHGLLKLRKSLNLFANIRPTFVTKGASHLSPLKQDI 122 Query: 495 AEGVDIMVVRELTGGIYFGKP 557 EG D+++VRELT GIYFG+P Sbjct: 123 VEGTDLVIVRELTSGIYFGEP 143
>LEU3_STAEQ (Q5HMF8) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 347 Score = 114 bits (286), Expect = 1e-25 Identities = 60/141 (42%), Positives = 83/141 (58%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I LPGDGIGPE+++ ++L K E + PL +ETL + + Sbjct: 5 IVALPGDGIGPEILSGTLELLKLISEKYHFEYHLESHHFGGVSIDYYGTPLTNETLQSCK 64 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 +DAILLGAIGG KW + + +PE GLL +R L +FAN+RP V S LK+++ Sbjct: 65 NADAILLGAIGGPKW--TDPNNRPEHGLLKLRKSLNLFANIRPTFVTKGASHLSPLKQDI 122 Query: 495 AEGVDIMVVRELTGGIYFGKP 557 EG D+++VRELT GIYFG+P Sbjct: 123 VEGTDLVIVRELTSGIYFGEP 143
>LEU3_STAHJ (Q4L7U1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 346 Score = 114 bits (286), Expect = 1e-25 Identities = 59/142 (41%), Positives = 83/142 (58%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I LPGDGIGPE+++ ++L K + + VPLPD+TL A + Sbjct: 5 IVALPGDGIGPEILSGTLELLELISKKYKFDYQLTSYDFGGAAIDSHGVPLPDDTLNACK 64 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 +DAILLGA+GG +W + + +PE GLL +R LG+FAN+RP V S +K Sbjct: 65 NADAILLGAVGGPQW--TDPNNRPEQGLLALRKSLGLFANIRPTKVTEGTSHFSPIKESR 122 Query: 495 AEGVDIMVVRELTGGIYFGKPR 560 +G D ++VRELT G+YFG+PR Sbjct: 123 VKGTDFIIVRELTSGLYFGEPR 144
>LEU3_STRMU (Q8DTG3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 344 Score = 114 bits (286), Expect = 1e-25 Identities = 64/140 (45%), Positives = 82/140 (58%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I L GDGIGPE++A +V A K + + PLPD+TLAAA+ Sbjct: 4 IVTLAGDGIGPEIMAAGLEVFDAVAQKINFDYEIEAKAFGGAGIDASGHPLPDDTLAAAK 63 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 +DAILL AIG ++D + ++PE GLL IR L +FAN+RP + L S LK E Sbjct: 64 TADAILLAAIGSPQYD--KAPVRPEQGLLAIRKELNLFANIRPVRIFDALRHLSPLKAER 121 Query: 495 AEGVDIMVVRELTGGIYFGK 554 GVD +VVRELTGGIYFG+ Sbjct: 122 IAGVDFVVVRELTGGIYFGQ 141
>LEU3A_ASPNG (P87256) 3-isopropylmalate dehydrogenase A (EC 1.1.1.85) (Beta-IPM| dehydrogenase A) (IMDH A) (3-IPM-DH A) Length = 363 Score = 114 bits (286), Expect = 1e-25 Identities = 66/141 (46%), Positives = 82/141 (58%), Gaps = 2/141 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAG-SKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAA 311 I + GD GPEV A A VL S++ + L ++ PL DE LAAA Sbjct: 6 IVVFAGDHWGPEVTAEAIKVLRVIEKSRDDITLNLQDHLLGGASIDATANPLTDEALAAA 65 Query: 312 RASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPAT-VLPQLVDASTLKR 488 + +DA+LLGAIGG KW ++PE GLLN+R +G F NLRP P LV+ S LK Sbjct: 66 KNADAVLLGAIGGPKWGTGA--VRPEQGLLNVRKEMGTFGNLRPCNFAAPSLVEHSPLKA 123 Query: 489 EVAEGVDIMVVRELTGGIYFG 551 V EGVD ++RELTGGIYFG Sbjct: 124 SVCEGVDFNIIRELTGGIYFG 144
>LEU3_PHOPR (Q6LV25) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 362 Score = 114 bits (285), Expect = 2e-25 Identities = 65/144 (45%), Positives = 85/144 (59%), Gaps = 2/144 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +LPGDGIGPEV+ A VL A K G L E PLP+ T+ Sbjct: 7 IAVLPGDGIGPEVMLQAHKVLDAVEEKFGFTLERSEHDVGGIAIDNHGCPLPESTMKGCE 66 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETG-LLNIRAGLGVFANLRPATVLPQLVDASTLKRE 491 SDAIL G++GG KW++ + +PE G LL +R +F NLRPA + L S L+ + Sbjct: 67 ESDAILFGSVGGPKWEHLAPNDQPERGALLPLRKHFQLFCNLRPAQIHSGLEGFSPLRAD 126 Query: 492 VAE-GVDIMVVRELTGGIYFGKPR 560 ++E G DI+VVRELTGGIYFG+P+ Sbjct: 127 ISERGFDIVVVRELTGGIYFGQPK 150
>LEU3_STRT2 (Q5M405) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 345 Score = 114 bits (284), Expect = 2e-25 Identities = 67/140 (47%), Positives = 81/140 (57%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I L GDGIGPE++A VL SK + PLP TL AA+ Sbjct: 5 IVTLSGDGIGPEIMAAGLGVLDKVASKIEFDYDVDAKPFGGAGIDAEGHPLPKATLEAAK 64 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 ++DAILL AIGG K+DN ++PE GLL IR L +FAN+RP + L S LK E Sbjct: 65 SADAILLAAIGGPKYDNAP--VRPEQGLLAIRKELNLFANIRPVRIFDALKHLSPLKPER 122 Query: 495 AEGVDIMVVRELTGGIYFGK 554 EGVD +VVRELTGGIYFG+ Sbjct: 123 IEGVDFVVVRELTGGIYFGE 142
>LEU3_STRT1 (Q5LZF3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 345 Score = 114 bits (284), Expect = 2e-25 Identities = 67/140 (47%), Positives = 81/140 (57%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I L GDGIGPE++A VL SK + PLP TL AA+ Sbjct: 5 IVTLSGDGIGPEIMAAGLGVLDKVASKIEFDYDVDAKPFGGAGIDAEGHPLPKATLEAAK 64 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 ++DAILL AIGG K+DN ++PE GLL IR L +FAN+RP + L S LK E Sbjct: 65 SADAILLAAIGGPKYDNAP--VRPEQGLLAIRKELNLFANIRPVRIFDALKHLSPLKPER 122 Query: 495 AEGVDIMVVRELTGGIYFGK 554 EGVD +VVRELTGGIYFG+ Sbjct: 123 IEGVDFVVVRELTGGIYFGE 142
>LEU3_VIBVY (Q7MP78) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 113 bits (283), Expect = 3e-25 Identities = 63/144 (43%), Positives = 85/144 (59%), Gaps = 2/144 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +LPGDGIGPEV+A A VL A K + +E PLP T+ A Sbjct: 8 IAVLPGDGIGPEVMAQAHKVLDAIEKKHAIHFEREEHDVGGIAIDNHGCPLPQSTVTACE 67 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETG-LLNIRAGLGVFANLRPATVLPQLVDASTLKRE 491 SDA+L G++GG KW++ + +PE G LL +R +F NLRPA + L S L+ + Sbjct: 68 ESDAVLFGSVGGPKWEHLPPNDQPERGALLPLRKHFQLFCNLRPAQIHSGLEAFSPLRAD 127 Query: 492 VA-EGVDIMVVRELTGGIYFGKPR 560 ++ G DI+VVRELTGGIYFG+P+ Sbjct: 128 ISGRGFDIVVVRELTGGIYFGQPK 151
>LEU3_VIBVU (Q8DEE0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 113 bits (283), Expect = 3e-25 Identities = 63/144 (43%), Positives = 85/144 (59%), Gaps = 2/144 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +LPGDGIGPEV+A A VL A K + +E PLP T+ A Sbjct: 8 IAVLPGDGIGPEVMAQAHKVLDAIEKKHAIHFEREEHDVGGIAIDNHGCPLPQSTVTACE 67 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETG-LLNIRAGLGVFANLRPATVLPQLVDASTLKRE 491 SDA+L G++GG KW++ + +PE G LL +R +F NLRPA + L S L+ + Sbjct: 68 ESDAVLFGSVGGPKWEHLPPNDQPERGALLPLRKHFQLFCNLRPAQIHSGLEAFSPLRAD 127 Query: 492 VA-EGVDIMVVRELTGGIYFGKPR 560 ++ G DI+VVRELTGGIYFG+P+ Sbjct: 128 ISGRGFDIVVVRELTGGIYFGQPK 151
>LEU3_YEAST (P04173) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 364 Score = 113 bits (282), Expect = 4e-25 Identities = 63/142 (44%), Positives = 84/142 (59%), Gaps = 2/142 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGS-KEGVELRYKEXXXXXXXXXXXXVPLPDETLAAA 311 I +LPGD +G E+ A A VL A + V+ ++ VPLPDE L A+ Sbjct: 7 IVVLPGDHVGQEITAEAIKVLKAISDVRSNVKFDFENHLIGGAAIDATGVPLPDEALEAS 66 Query: 312 RASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPAT-VLPQLVDASTLKR 488 + +DA+LLGA+GG KW ++PE GLL IR L ++ANLRP L+D S +K Sbjct: 67 KKADAVLLGAVGGPKWGTGS--VRPEQGLLKIRKELQLYANLRPCNFASDSLLDLSPIKP 124 Query: 489 EVAEGVDIMVVRELTGGIYFGK 554 + A+G D +VVREL GGIYFGK Sbjct: 125 QFAKGTDFVVVRELVGGIYFGK 146
>LEU3_SACEX (Q96WT9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 365 Score = 113 bits (282), Expect = 4e-25 Identities = 63/142 (44%), Positives = 84/142 (59%), Gaps = 2/142 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGS-KEGVELRYKEXXXXXXXXXXXXVPLPDETLAAA 311 I +LPGD +G E+ A VL+A S + V ++ VPLPDE L A+ Sbjct: 8 IVVLPGDHVGQEITEEAIKVLNAISSVRPNVNFDFQHHLIGGAAIDATGVPLPDEALEAS 67 Query: 312 RASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPAT-VLPQLVDASTLKR 488 + +DA+LLGA+GG KW ++PE GLL IR L ++ANLRP L+D S LK Sbjct: 68 KKADAVLLGAVGGPKWGTGS--VRPEQGLLKIRKELQLYANLRPCNFASDSLLDLSPLKP 125 Query: 489 EVAEGVDIMVVRELTGGIYFGK 554 E+ +G DI +VREL GGIYFG+ Sbjct: 126 EIVKGTDICIVRELVGGIYFGE 147
>LEU3_PICJA (P08791) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 113 bits (282), Expect = 4e-25 Identities = 62/142 (43%), Positives = 85/142 (59%), Gaps = 2/142 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGS-KEGVELRYKEXXXXXXXXXXXXVPLPDETLAAA 311 I +LPGD +G E+ A A VL A K ++ ++ VPLPD+ L A+ Sbjct: 6 IVVLPGDHVGTEITAEAIKVLKAIEEVKPEIKFNFQHHLIGGAAIDATGVPLPDDALEAS 65 Query: 312 RASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQ-LVDASTLKR 488 + +DA+LLGA+GG KW ++PE GLL IR L ++ANLRP + L+D S +K Sbjct: 66 KKADAVLLGAVGGPKWGTGA--VRPEQGLLKIRKELNLYANLRPCNFASESLLDLSPIKA 123 Query: 489 EVAEGVDIMVVRELTGGIYFGK 554 EV +G D +VVREL GGIYFG+ Sbjct: 124 EVVKGTDFVVVRELVGGIYFGE 145
>LEU3_KLULA (P23390) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 362 Score = 112 bits (281), Expect = 5e-25 Identities = 64/142 (45%), Positives = 85/142 (59%), Gaps = 2/142 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSA-AGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAA 311 I +LPGD +G EV A VL+A A + ++ ++ PLPDE L A+ Sbjct: 5 IVVLPGDHVGKEVTDEAIKVLNAIAEVRPEIKFNFQHHLIGGAAIDATGTPLPDEALEAS 64 Query: 312 RASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQ-LVDASTLKR 488 + +DA+LLGA+GG KW ++PE GLL IR LG++ANLRP L+D S LK Sbjct: 65 KKADAVLLGAVGGPKWGTGA--VRPEQGLLKIRKELGLYANLRPCNFASDSLLDLSPLKP 122 Query: 489 EVAEGVDIMVVRELTGGIYFGK 554 E A+G D +VVREL GGIYFG+ Sbjct: 123 EYAKGTDFVVVRELVGGIYFGE 144
>LEU3_PICST (O94114) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 373 Score = 112 bits (281), Expect = 5e-25 Identities = 64/144 (44%), Positives = 85/144 (59%), Gaps = 4/144 (2%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSA---AGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLA 305 IT+LPGD +G E+ A VL A A + + +K VPLPD++LA Sbjct: 8 ITVLPGDHVGTEICNEAIKVLEAIEQATPYQKIHFEFKHHLIGGAAIDSTGVPLPDDSLA 67 Query: 306 AARASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQ-LVDASTL 482 AA+ SDA+LLGA+GG KW ++PE GLL IR L ++ANLRP L++ S L Sbjct: 68 AAKLSDAVLLGAVGGPKWGTGA--VRPEQGLLKIRKELNLYANLRPCNFASDALLELSPL 125 Query: 483 KREVAEGVDIMVVRELTGGIYFGK 554 K E+ +G + VVREL GGIYFG+ Sbjct: 126 KSEIVKGTNFTVVRELVGGIYFGE 149
>LEU3_HAEI8 (Q4QLS3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 358 Score = 112 bits (281), Expect = 5e-25 Identities = 64/144 (44%), Positives = 85/144 (59%), Gaps = 2/144 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 + +L GDGIGPEV+A A VL+ K G +L + E PLP ETL Sbjct: 6 VAVLAGDGIGPEVMAEAMKVLNKVQEKFGFKLNFNEFFVGGAAIDHCGYPLPAETLKGCD 65 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETG-LLNIRAGLGVFANLRPATVLPQLVDASTLKRE 491 +DAIL G++GG KW N +PE G LL +R +F NLRPAT+ L L+ + Sbjct: 66 EADAILFGSVGGPKWTNLPPDQQPERGALLPLRKHFKLFCNLRPATLYKGLEKFCPLRAD 125 Query: 492 V-AEGVDIMVVRELTGGIYFGKPR 560 + A+G D++VVRELTGGIYFG+P+ Sbjct: 126 IAAKGFDMVVVRELTGGIYFGQPK 149
>LEU3_HAEIN (P43860) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 358 Score = 112 bits (280), Expect = 7e-25 Identities = 65/144 (45%), Positives = 85/144 (59%), Gaps = 2/144 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +L GDGIGPEV+A A VL+ K G +L + E PLP ETL Sbjct: 6 IAVLAGDGIGPEVMAEAIKVLNRVQEKFGFKLNFNEFFVGGAAIEHCGYPLPAETLKGCD 65 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETG-LLNIRAGLGVFANLRPATVLPQLVDASTLKRE 491 +DAIL G++GG KW N +PE G LL +R +F NLRPAT+ L L+ + Sbjct: 66 QADAILFGSVGGPKWTNLPPDQQPERGALLPLRKHFKLFCNLRPATLYKGLEKFCPLRAD 125 Query: 492 V-AEGVDIMVVRELTGGIYFGKPR 560 + A+G D++VVRELTGGIYFG+P+ Sbjct: 126 IAAKGFDMVVVRELTGGIYFGQPK 149
>LEU3_VIBF1 (Q5E857) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 112 bits (279), Expect = 9e-25 Identities = 61/144 (42%), Positives = 86/144 (59%), Gaps = 2/144 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +LPGDGIGPEV+ A VL A K + ++ PLP+ T+ Sbjct: 8 IAVLPGDGIGPEVMEQAHKVLDAIEKKHAISFSREQHDVGGIAIDNHGCPLPESTVKGCE 67 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETG-LLNIRAGLGVFANLRPATVLPQLVDASTLKRE 491 SDA+L G++GG KW++ + +PE G LL +R +F NLRPA + L + S L+ + Sbjct: 68 ESDAVLFGSVGGPKWEHLPPNDQPERGALLPLRKHFQLFCNLRPAQIHKGLENFSPLRAD 127 Query: 492 VAE-GVDIMVVRELTGGIYFGKPR 560 ++E G DI+VVRELTGGIYFG+P+ Sbjct: 128 ISERGFDIVVVRELTGGIYFGQPK 151
>LEU3_MANSM (Q65V05) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 358 Score = 111 bits (278), Expect = 1e-24 Identities = 63/144 (43%), Positives = 86/144 (59%), Gaps = 2/144 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 + +LPGDGIGPEV+A A VL +K G +L + + PLP ETL Sbjct: 6 VAVLPGDGIGPEVMAEAIKVLDKVQAKFGFKLNFTQYLVGGAAIDAKGEPLPAETLQGCD 65 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETG-LLNIRAGLGVFANLRPATVLPQLVDASTLKRE 491 +DAIL G++GG KW + +PE G LL +R +F NLRPAT+ L L+ + Sbjct: 66 NADAILFGSVGGPKWTHLPPDQQPERGALLPLRKHFKLFCNLRPATLYKGLEKFCPLRAD 125 Query: 492 V-AEGVDIMVVRELTGGIYFGKPR 560 + A+G D++VVRELTGGIYFG+P+ Sbjct: 126 IAAKGFDMVVVRELTGGIYFGQPK 149
>LEU3_ARXAD (Q8NKB8) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 362 Score = 111 bits (278), Expect = 1e-24 Identities = 62/141 (43%), Positives = 84/141 (59%), Gaps = 2/141 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSA-AGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAA 311 I +L GD +GPEV A A VL A ++ V+ + PLPDETL A+ Sbjct: 5 IIILSGDHVGPEVTAEAIKVLEAITQARPNVKFNFDHKLIGGAAIDATGSPLPDETLEAS 64 Query: 312 RASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQ-LVDASTLKR 488 + +DA+LLGA+GG KW ++PE GLL IR L ++ANLRP + + L+D S L+ Sbjct: 65 KKADAVLLGAVGGPKWGTGA--VRPEQGLLKIRKELNLYANLRPCNFMSEKLLDLSPLRS 122 Query: 489 EVAEGVDIMVVRELTGGIYFG 551 E+ +G + VVREL GGIYFG Sbjct: 123 EIVKGTNFTVVRELVGGIYFG 143
>LEU3_CANAL (P87186) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 373 Score = 110 bits (276), Expect = 2e-24 Identities = 60/144 (41%), Positives = 87/144 (60%), Gaps = 4/144 (2%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSK---EGVELRYKEXXXXXXXXXXXXVPLPDETLA 305 IT+LPGD +G E+V VL A + + ++ +K VPLPD+ L Sbjct: 8 ITVLPGDHVGTEIVNEPTKVLKAIEAPTPYQKIQFDFKHHLIGGAAIDATGVPLPDDALE 67 Query: 306 AARASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPAT-VLPQLVDASTL 482 +A++SDA+LLGA+GG KW ++PE GLL IR L ++AN+RP L++ S L Sbjct: 68 SAKSSDAVLLGAVGGPKWGTGT--VRPEQGLLKIRKELNLYANIRPCNFASDSLLELSPL 125 Query: 483 KREVAEGVDIMVVRELTGGIYFGK 554 K EV +G ++++VREL GGIYFG+ Sbjct: 126 KAEVVKGTNLIIVRELVGGIYFGE 149
>LEU3_CAMJR (Q5HS77) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 358 Score = 110 bits (276), Expect = 2e-24 Identities = 63/142 (44%), Positives = 78/142 (54%), Gaps = 2/142 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 + +L GDGIGP V+ A +L+ K + E V L DETL Sbjct: 6 VAVLAGDGIGPLVMKEALKILTFISQKYNFSFEFNEAKIGGASIDAYGVALSDETLKLCE 65 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPE-TGLLNIRAGLGVFANLRPATVLPQLVDASTLKRE 491 SDAIL G++GG KWDN +PE LL +R +FANLRP + L AS LK E Sbjct: 66 QSDAILFGSVGGPKWDNLPIDQRPERASLLPLRKHFNLFANLRPCKIYESLTHASPLKNE 125 Query: 492 VAE-GVDIMVVRELTGGIYFGK 554 + + GVDI+ VRELTGGIYFGK Sbjct: 126 IIQKGVDILCVRELTGGIYFGK 147
>LEU3_CAMJE (Q9PLW0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 358 Score = 110 bits (276), Expect = 2e-24 Identities = 63/142 (44%), Positives = 78/142 (54%), Gaps = 2/142 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 + +L GDGIGP V+ A +L+ K + E V L DETL Sbjct: 6 VAVLAGDGIGPLVMKEALKILTFIAQKYNFSFEFNEAKIGGASIDAYGVALSDETLKLCE 65 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPE-TGLLNIRAGLGVFANLRPATVLPQLVDASTLKRE 491 SDAIL G++GG KWDN +PE LL +R +FANLRP + L AS LK E Sbjct: 66 QSDAILFGSVGGPKWDNLPIDQRPERASLLPLRKHFNLFANLRPCKIYESLTHASPLKNE 125 Query: 492 VAE-GVDIMVVRELTGGIYFGK 554 + + GVDI+ VRELTGGIYFGK Sbjct: 126 IIQKGVDILCVRELTGGIYFGK 147
>LEU3_CANGA (O14429) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 365 Score = 110 bits (276), Expect = 2e-24 Identities = 63/143 (44%), Positives = 83/143 (58%), Gaps = 3/143 (2%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGS--KEGVELRYKEXXXXXXXXXXXXVPLPDETLAA 308 I +LPGD +G E+ A VL+A + V ++ VPLPDE L A Sbjct: 7 IVVLPGDHVGQEITEEAIKVLNAIQECRPDKVNFKFDHHLIGGAAIDATGVPLPDEALEA 66 Query: 309 ARASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQ-LVDASTLK 485 ++ +DA+LLGA+GG KW ++PE GLL IR L ++ANLRP L+D S LK Sbjct: 67 SKKADAVLLGAVGGPKWGTGA--VRPEQGLLKIRKELQLYANLRPCNFASDSLLDLSPLK 124 Query: 486 REVAEGVDIMVVRELTGGIYFGK 554 E+A G D +VVREL GGIYFG+ Sbjct: 125 PEIARGTDFVVVRELVGGIYFGE 147
>LEU3_ERWCT (Q6D0G7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 110 bits (276), Expect = 2e-24 Identities = 62/144 (43%), Positives = 85/144 (59%), Gaps = 2/144 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +LPGDGIGPEV+A A VL A + G+ + E PLP T+A Sbjct: 7 IAVLPGDGIGPEVMAQAHKVLDAVRQRFGIRITTSEYDVGGIAIDRQGTPLPQATVAGCE 66 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETG-LLNIRAGLGVFANLRPATVLPQLVDASTLKRE 491 +DAIL G++GG KW++ +PE G LL +R +F+NLRPA + L L+ + Sbjct: 67 QADAILFGSVGGPKWEHLPPAEQPERGALLPLRKHFKLFSNLRPARLYQGLEAFCPLRSD 126 Query: 492 V-AEGVDIMVVRELTGGIYFGKPR 560 + A+G DI+ VRELTGGIYFG+P+ Sbjct: 127 IAAKGFDILCVRELTGGIYFGQPK 150
>LEU3_PASMU (Q9CJN6) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 359 Score = 110 bits (275), Expect = 3e-24 Identities = 61/144 (42%), Positives = 83/144 (57%), Gaps = 2/144 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +L GDGIGPE++A A VL K +L Y+ PLP+ TL Sbjct: 6 IAVLSGDGIGPEIIAEAIKVLDVVQQKYAFKLNYRTFDVGGIAIDNHGTPLPEATLKGCE 65 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETG-LLNIRAGLGVFANLRPATVLPQLVDASTLKRE 491 SDAIL G++GG KW++ +PE G LL +R +F NLRPAT+ L L+ + Sbjct: 66 ESDAILFGSVGGPKWEHLPPAQQPERGALLPLRKHFALFCNLRPATLYKGLEKFCPLRAD 125 Query: 492 V-AEGVDIMVVRELTGGIYFGKPR 560 + A+G D++ VRELTGGIYFG+P+ Sbjct: 126 ISAKGFDMVTVRELTGGIYFGQPK 149
>LEU3_HANAN (Q9HDQ1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 364 Score = 110 bits (275), Expect = 3e-24 Identities = 62/142 (43%), Positives = 83/142 (58%), Gaps = 2/142 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGS-KEGVELRYKEXXXXXXXXXXXXVPLPDETLAAA 311 I +LPGD +G E+ A VL A + V+ ++ VPLPDE L AA Sbjct: 6 IVVLPGDHVGTEITNEAIKVLKAIEEVRPNVKFNFQHHLIGGAAIDATGVPLPDEALEAA 65 Query: 312 RASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQ-LVDASTLKR 488 + +DA+LLGA+GG KW ++PE GLL IR L ++ANLRP + L++ S +K Sbjct: 66 KKADAVLLGAVGGPKWGTGA--VRPEQGLLKIRKELNLYANLRPCNFASESLLELSPIKA 123 Query: 489 EVAEGVDIMVVRELTGGIYFGK 554 E A+G D VVREL GGIYFG+ Sbjct: 124 EFAKGTDFTVVRELVGGIYFGE 145
>LEU3_CANMA (P07139) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 373 Score = 110 bits (275), Expect = 3e-24 Identities = 62/143 (43%), Positives = 85/143 (59%), Gaps = 4/143 (2%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSA---AGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLA 305 IT+LPGD +G E+V A VL A A + + +K VPLPD+ L Sbjct: 8 ITILPGDHVGTEIVNEAIKVLEAIEAATPYQKIHFDFKHHLIGGAAIDATGVPLPDDALE 67 Query: 306 AARASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPAT-VLPQLVDASTL 482 +A+ SDA+LLGA+GG KW L+PE GLL IR L ++AN+RP L++ S L Sbjct: 68 SAKNSDAVLLGAVGGPKWGTGA--LRPEQGLLKIRKELNLYANIRPCNFASDSLLELSPL 125 Query: 483 KREVAEGVDIMVVRELTGGIYFG 551 + EV +G ++++VREL GGIYFG Sbjct: 126 RPEVVKGTNLIIVRELVGGIYFG 148
>LEU3_DEBHA (Q6B458) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 382 Score = 110 bits (275), Expect = 3e-24 Identities = 64/144 (44%), Positives = 83/144 (57%), Gaps = 4/144 (2%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSA---AGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLA 305 IT+LPGD +G EV A VL A A ++ ++ PLPDE+L Sbjct: 17 ITVLPGDHVGEEVCNEAIKVLQAIEDATPYRNIKFNLQKHLIGGAAIDATGTPLPDESLE 76 Query: 306 AARASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPAT-VLPQLVDASTL 482 AA+ SDA+LLGA+GG KW ++PE GLL IR L ++ANLRP L++ S L Sbjct: 77 AAKNSDAVLLGAVGGPKWGTGS--VRPEQGLLKIRKELNLYANLRPCNFASDSLLELSPL 134 Query: 483 KREVAEGVDIMVVRELTGGIYFGK 554 K E+ +G D VVREL GGIYFG+ Sbjct: 135 KSEIVKGTDFTVVRELVGGIYFGE 158
>LEU3_BUCUA (Q9EVG6) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 110 bits (274), Expect = 4e-24 Identities = 62/143 (43%), Positives = 83/143 (58%), Gaps = 2/143 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +LPGDGIGPEV+ A +L+ + L KE V LP +TL Sbjct: 7 IAVLPGDGIGPEVMREAYKILNILKDDFSLPLEIKEFNIGGAAIDQEGVALPKKTLLGCE 66 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPE-TGLLNIRAGLGVFANLRPATVLPQLVDASTLKRE 491 SDAIL G++GG KWDN + +PE LL +R +FANLRPA + +L + S L+ Sbjct: 67 NSDAILFGSVGGKKWDNLPINQRPERASLLPLRKHFNLFANLRPAQLYSELKNLSPLRSN 126 Query: 492 VAE-GVDIMVVRELTGGIYFGKP 557 + + G +I+ +RELTGGIYFGKP Sbjct: 127 IIKNGFNILCIRELTGGIYFGKP 149
>LEU3_YERPS (Q66EM2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 109 bits (273), Expect = 5e-24 Identities = 62/144 (43%), Positives = 85/144 (59%), Gaps = 2/144 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +LPGDGIGPEV+A A VL A + G+++ PLP T+A Sbjct: 7 IAVLPGDGIGPEVMAQASKVLDAVRQRFGLKISTSVYDVGGAAIDRHGSPLPAATVAGCE 66 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETG-LLNIRAGLGVFANLRPATVLPQLVDASTLKRE 491 +DAIL G++GG KW++ +PE G LL +R +F+NLRPA + L D L+ + Sbjct: 67 QADAILFGSVGGPKWEHLPPAEQPERGALLPLRKHFKLFSNLRPARLYQGLEDFCPLRSD 126 Query: 492 V-AEGVDIMVVRELTGGIYFGKPR 560 + A G DI+ VRELTGGIYFG+P+ Sbjct: 127 IAARGFDILCVRELTGGIYFGQPK 150
>LEU3_YERPE (Q8ZIG9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 109 bits (273), Expect = 5e-24 Identities = 62/144 (43%), Positives = 85/144 (59%), Gaps = 2/144 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +LPGDGIGPEV+A A VL A + G+++ PLP T+A Sbjct: 7 IAVLPGDGIGPEVMAQASKVLDAVRQRFGLKISTSVYDVGGAAIDRHGSPLPAATVAGCE 66 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETG-LLNIRAGLGVFANLRPATVLPQLVDASTLKRE 491 +DAIL G++GG KW++ +PE G LL +R +F+NLRPA + L D L+ + Sbjct: 67 QADAILFGSVGGPKWEHLPPAEQPERGALLPLRKHFKLFSNLRPARLYQGLEDFCPLRSD 126 Query: 492 V-AEGVDIMVVRELTGGIYFGKPR 560 + A G DI+ VRELTGGIYFG+P+ Sbjct: 127 IAARGFDILCVRELTGGIYFGQPK 150
>LEU3_BACFR (P54354) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 353 Score = 108 bits (271), Expect = 8e-24 Identities = 57/141 (40%), Positives = 82/141 (58%), Gaps = 1/141 (0%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +L GDGIGPE+ +V+SA K G ++ Y+ P P+ET + Sbjct: 5 IAVLAGDGIGPEISVQGVEVMSAVCEKFGHKVNYEYAICGADAIDKVGDPFPEETYRVCK 64 Query: 315 ASDAILLGAIGGYKWDNNEK-HLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKRE 491 +DA+L A+G K+DN+ ++PE GLL +R LG+FAN+RP LV S L+ E Sbjct: 65 NADAVLFSAVGDPKFDNDPTAKVRPEQGLLAMRKKLGLFANIRPVQTFKCLVHKSPLRAE 124 Query: 492 VAEGVDIMVVRELTGGIYFGK 554 + EG D + +RELTGG+YFG+ Sbjct: 125 LVEGADFLCIRELTGGMYFGE 145
>LEU3_BACFN (Q5LAB4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 353 Score = 108 bits (271), Expect = 8e-24 Identities = 57/141 (40%), Positives = 82/141 (58%), Gaps = 1/141 (0%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +L GDGIGPE+ +V+SA K G ++ Y+ P P+ET + Sbjct: 5 IAVLAGDGIGPEISVQGVEVMSAVCEKFGHKVNYEYAICGADAIDKVGDPFPEETYRVCK 64 Query: 315 ASDAILLGAIGGYKWDNNEK-HLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKRE 491 +DA+L A+G K+DN+ ++PE GLL +R LG+FAN+RP LV S L+ E Sbjct: 65 NADAVLFSAVGDPKFDNDPTAKVRPEQGLLAMRKKLGLFANIRPVQTFKCLVHKSPLRAE 124 Query: 492 VAEGVDIMVVRELTGGIYFGK 554 + EG D + +RELTGG+YFG+ Sbjct: 125 LVEGADFLCIRELTGGMYFGE 145
>LEU3_BUCRP (P48572) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 108 bits (271), Expect = 8e-24 Identities = 61/144 (42%), Positives = 81/144 (56%), Gaps = 2/144 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +LPGDGIGPE++ A +L+ + L +E + LP+ETL Sbjct: 7 IAVLPGDGIGPEIMREAYKILNILEKNFSLPLEIREFSVGGIAIDREGIALPEETLRGCE 66 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPE-TGLLNIRAGLGVFANLRPATVLPQLVDASTLKRE 491 SDAIL G++GG KWD +PE LL +R +F+NLRPA + L + S L+ Sbjct: 67 NSDAILFGSVGGKKWDYLPIESRPERASLLPLRKHFNLFSNLRPAKLYSDLKNLSPLRSN 126 Query: 492 -VAEGVDIMVVRELTGGIYFGKPR 560 V G DI+ VRELTGGIYFGKP+ Sbjct: 127 IVRNGFDILCVRELTGGIYFGKPK 150
>LEU3_BUCAP (O85064) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 108 bits (271), Expect = 8e-24 Identities = 61/144 (42%), Positives = 85/144 (59%), Gaps = 2/144 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +LPGDGIGPEV+ A +L+ K ++L +E + LP++TL Sbjct: 7 IAVLPGDGIGPEVMREAYKILNILERKFFLKLELREFDIGGIAIDREGIALPEKTLRGCE 66 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPE-TGLLNIRAGLGVFANLRPATVLPQLVDASTLKRE 491 SDAIL G++GG KWD +PE LL +R +F+NLRPA + L + S L+ + Sbjct: 67 NSDAILFGSVGGKKWDYLPIESRPERASLLPLRKHFNLFSNLRPAKLRVDLKNLSPLRSD 126 Query: 492 -VAEGVDIMVVRELTGGIYFGKPR 560 V +G DI+ +RELTGGIYFGKP+ Sbjct: 127 IVRDGFDILCIRELTGGIYFGKPK 150
>LEU3_KLUMA (P41766) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 359 Score = 108 bits (270), Expect = 1e-23 Identities = 62/142 (43%), Positives = 85/142 (59%), Gaps = 2/142 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAG-SKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAA 311 I +LPGD +G E+ A VL+A ++ ++ ++ VPLPDE A+ Sbjct: 5 IVVLPGDHVGTEITNEAIKVLNAISEARPSIKFNFEHHLIGGAAIDATGVPLPDE---AS 61 Query: 312 RASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQ-LVDASTLKR 488 + +DA+LLGA+GG KW ++PE GLL IR LG++ANLRP L+D S LK Sbjct: 62 KKADAVLLGAVGGPKWGTGS--VRPEQGLLKIRKELGLYANLRPCNFASDSLLDLSPLKP 119 Query: 489 EVAEGVDIMVVRELTGGIYFGK 554 E A+G D +VVREL GGIYFG+ Sbjct: 120 EYAKGTDFVVVRELVGGIYFGE 141
>LEU3_ASHGO (O60027) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 372 Score = 108 bits (269), Expect = 1e-23 Identities = 65/142 (45%), Positives = 81/142 (57%), Gaps = 2/142 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAG-SKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAA 311 I +LPGD IG EVV A VL A S V ++ LPDE L AA Sbjct: 7 IVVLPGDHIGREVVEEAVKVLGAVEQSLSDVHFDFQYHLVGGAAIDATGSALPDEALGAA 66 Query: 312 RASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPAT-VLPQLVDASTLKR 488 + +DA+LLGA+GG KW ++PE GLL +R LGV+ANLRP L++ S L+ Sbjct: 67 KEADAVLLGAVGGPKWQGGA--VRPEQGLLKLRQELGVYANLRPCNFAADSLLELSPLRP 124 Query: 489 EVAEGVDIMVVRELTGGIYFGK 554 E+A DIMVVREL GG YFG+ Sbjct: 125 EIARDTDIMVVRELLGGSYFGE 146
>LEU3_BLOFL (Q7VQJ7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 364 Score = 108 bits (269), Expect = 1e-23 Identities = 58/144 (40%), Positives = 87/144 (60%), Gaps = 2/144 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +LPGDGIGPE++ A +L+ +K + + E PLP +T+ Sbjct: 8 IAILPGDGIGPEIMQQAYKILNTVKNKFKINIITTEYKVGGNALDLEGSPLPKDTIKNCE 67 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETG-LLNIRAGLGVFANLRPATVLPQLVDASTLKRE 491 S+AIL GA+GG KW+N + +PE G LL +R +F NLRP + +L++ S LK E Sbjct: 68 KSNAILFGAVGGPKWNNINETSRPEFGALLTLRKHFNLFINLRPIYLPIELINLSPLKPE 127 Query: 492 -VAEGVDIMVVRELTGGIYFGKPR 560 +++G+D++ +REL GGIYFGKP+ Sbjct: 128 IISQGLDMICIRELIGGIYFGKPQ 151
>LEU3_BUCDN (O85071) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 108 bits (269), Expect = 1e-23 Identities = 62/144 (43%), Positives = 82/144 (56%), Gaps = 2/144 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +LPGDGIGPEV+ A +L + ++ KE + LP +TL Sbjct: 7 IAVLPGDGIGPEVMQEAYKILQVLREHFSLFIKTKEFDIGGIAIDNHGIALPKKTLIGCE 66 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPE-TGLLNIRAGLGVFANLRPATVLPQLVDASTLKRE 491 SDAILLG+IGG KWD + +PE LL +R F NLRP+ + +L S L+ + Sbjct: 67 NSDAILLGSIGGKKWDTLPINERPERASLLPLRKHFNFFCNLRPSNLYKELNFLSPLRND 126 Query: 492 VAE-GVDIMVVRELTGGIYFGKPR 560 + + G DI+ VRELTGGIYFGKPR Sbjct: 127 IVKHGFDILCVRELTGGIYFGKPR 150
>LEU3_BUCTS (O31292) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 364 Score = 107 bits (268), Expect = 2e-23 Identities = 57/142 (40%), Positives = 80/142 (56%), Gaps = 2/142 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +LPGDGIGPE++ A ++ K ++ E L ET+ Sbjct: 8 IAVLPGDGIGPEIIQEAYKIIDVLQKKFSFNVKMHEYDIGGISIDKHGTALTQETIEGCE 67 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPE-TGLLNIRAGLGVFANLRPATVLPQLVDASTLKRE 491 SDAIL G++GG KWD+ + KPE GLL +R +FAN+RP + L+D S LK Sbjct: 68 NSDAILFGSVGGSKWDHLPEIEKPEKAGLLKLRKHFNLFANIRPCKLSQHLLDISPLKNS 127 Query: 492 -VAEGVDIMVVRELTGGIYFGK 554 + +G+D++ +RELTGGIYFGK Sbjct: 128 IIKKGIDLICIRELTGGIYFGK 149
>LEU3_BUCUH (Q9EVH8) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 107 bits (268), Expect = 2e-23 Identities = 60/143 (41%), Positives = 83/143 (58%), Gaps = 2/143 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +LPGDGIGPEV+ A +LS + L +E + LP +TL + Sbjct: 7 IAILPGDGIGPEVMREAYKILSILKDHFSLSLEIQEFNIGGSAIDQEGIALPKKTLLGCQ 66 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPE-TGLLNIRAGLGVFANLRPATVLPQLVDASTLKRE 491 SDAIL G++GG +WD+ + +PE LL +R +FANLRPA + +L S ++ Sbjct: 67 NSDAILFGSVGGKRWDHLPINERPERASLLPLRKHFNLFANLRPAKLYSELQHLSPIRSN 126 Query: 492 VAE-GVDIMVVRELTGGIYFGKP 557 + + G DI+ VRELTGGIYFGKP Sbjct: 127 IIKNGFDILCVRELTGGIYFGKP 149
>LEU3_NEUCR (P34738) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 368 Score = 107 bits (267), Expect = 2e-23 Identities = 65/142 (45%), Positives = 80/142 (56%), Gaps = 3/142 (2%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSA--AGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAA 308 I + GD GPEVV A VL A S + + PL DE L A Sbjct: 6 IVVFGGDHCGPEVVLEAIKVLKAIETNSPSAGKFNLQNHLLGGASIDKHNDPLTDEALNA 65 Query: 309 ARASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQ-LVDASTLK 485 A+A+DA+LLGAIGG +W + ++PE GLL +R LG + NLRP + LVD+S LK Sbjct: 66 AKAADAVLLGAIGGPEWGTSST-VRPEQGLLKLRKELGTYGNLRPCNFASESLVDSSPLK 124 Query: 486 REVAEGVDIMVVRELTGGIYFG 551 EV G D +VVRELTGGIYFG Sbjct: 125 AEVCRGTDFIVVRELTGGIYFG 146
>LEU3_BACME (P41019) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 367 Score = 107 bits (266), Expect = 3e-23 Identities = 50/87 (57%), Positives = 62/87 (71%) Frame = +3 Query: 297 TLAAARASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDAS 476 T+ +DA+LLG++GG KWD HL+PE GLL IR L ++ANLRP T L DAS Sbjct: 57 TIETCNEADAVLLGSVGGPKWDRFPSHLRPEKGLLAIRKELDLYANLRPVTFYDSLADAS 116 Query: 477 TLKREVAEGVDIMVVRELTGGIYFGKP 557 LK+E EGVD ++VRELTGG+YFGKP Sbjct: 117 PLKKEYIEGVDFIIVRELTGGLYFGKP 143
>LEU3_BUCUM (Q9EVG9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 365 Score = 107 bits (266), Expect = 3e-23 Identities = 61/144 (42%), Positives = 83/144 (57%), Gaps = 3/144 (2%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I++LPGDGIGPEV+ A +L+ + + L KE V LP +TL Sbjct: 7 ISVLPGDGIGPEVMREAYKILNILKNHFSLPLEIKEFNIGGAAIDQEGVALPKKTLLGCE 66 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPE-TGLLNIRAGLGVFANLRPATVLPQLVDASTLKRE 491 SDAIL G++GG KWD+ +PE LL +R +FANLRPA + +L S L+ + Sbjct: 67 NSDAILFGSVGGKKWDHLPIDKRPERASLLPLRKHFNLFANLRPAQLYSELKYLSPLRSD 126 Query: 492 VA--EGVDIMVVRELTGGIYFGKP 557 + G +I+ +RELTGGIYFGKP Sbjct: 127 IXIKNGFNILCIRELTGGIYFGKP 150
>LEU3_BUCBP (P59515) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 366 Score = 107 bits (266), Expect = 3e-23 Identities = 62/144 (43%), Positives = 82/144 (56%), Gaps = 2/144 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +LPGDGIGPE++ +L SK + + +E V LP +TL R Sbjct: 7 IAVLPGDGIGPEIMREGYKILRILKSKLSLNIMTQEFDVGGVAIDKYGVALPKKTLQGCR 66 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETG-LLNIRAGLGVFANLRPATVLPQLVDASTLKRE 491 S AIL G+IGG KW++ HL+PE G LL +R +F+NLR A + L S LK Sbjct: 67 DSHAILFGSIGGPKWEDLPSHLQPERGALLPLRKYFNLFSNLRLARIYSGLEKLSPLKSR 126 Query: 492 VAE-GVDIMVVRELTGGIYFGKPR 560 ++ G DI+ VRELTGGIYFG P+ Sbjct: 127 ISNLGCDILCVRELTGGIYFGDPK 150
>LEU3_BACTN (Q8A6M0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 353 Score = 107 bits (266), Expect = 3e-23 Identities = 56/141 (39%), Positives = 81/141 (57%), Gaps = 1/141 (0%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +L GDGIGPE+ DV+SA K G ++ Y+ P P+ET + Sbjct: 5 IAVLAGDGIGPEISVQGVDVMSAVCEKFGHKVSYEYAICGADAIDKVGDPFPEETYEVCK 64 Query: 315 ASDAILLGAIGGYKWDNNEK-HLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKRE 491 +DA+L A+G K+DN+ ++PE GLL +R LG+FAN+RP L+ S L+ E Sbjct: 65 NADAVLFSAVGDPKFDNDPTAKVRPEQGLLAMRKKLGLFANIRPVQTFKCLIHKSPLRAE 124 Query: 492 VAEGVDIMVVRELTGGIYFGK 554 + E D + +RELTGG+YFG+ Sbjct: 125 LVENADFICIRELTGGMYFGE 145
>LEU3_STRR6 (Q8DPJ4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 345 Score = 106 bits (265), Expect = 4e-23 Identities = 61/139 (43%), Positives = 78/139 (56%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I L GDGIGPE++ +VL A K G + PLPDETL A+R Sbjct: 5 IVALVGDGIGPEIMEAGLEVLEALAEKTGFDYEIDRRPFGGADIDAAGPPLPDETLKASR 64 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 +DAILL AIG ++D ++PE GL+ +R L ++AN+RP + L S LK E Sbjct: 65 EADAILLVAIGSPQYDGVA--VRPEQGLMALRKELNLYANIRPVKIFDSLKYLSPLKPER 122 Query: 495 AEGVDIMVVRELTGGIYFG 551 GVD +VVRELTG IYFG Sbjct: 123 ISGVDFVVVRELTGEIYFG 141
>LEU3_LACLA (Q02143) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 345 Score = 106 bits (265), Expect = 4e-23 Identities = 60/140 (42%), Positives = 82/140 (58%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I L GDGIGPE+++ VL A K E + PLP+ETL A + Sbjct: 5 IVTLAGDGIGPEIMSAGLSVLKAVSKKIDFEYELEAKDFGGIAIDKHGHPLPEETLQAVK 64 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 +DAILL AIG K++N + ++PE GLL +R LG++AN+RP + P L S ++ Sbjct: 65 NADAILLAAIGHPKYNNAK--VRPEQGLLALRKELGLYANVRPLKIYPALKKLSPIRN-- 120 Query: 495 AEGVDIMVVRELTGGIYFGK 554 E VD +V+RELTGGIYFG+ Sbjct: 121 VENVDFLVIRELTGGIYFGQ 140
>LEU3_SORMA (Q6TWC4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 368 Score = 106 bits (265), Expect = 4e-23 Identities = 64/142 (45%), Positives = 80/142 (56%), Gaps = 3/142 (2%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSA--AGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAA 308 I + GD GPEVV A VL + S + + PL DE L A Sbjct: 6 IVVFGGDHCGPEVVVEAIKVLKSIETNSPSAGKFNLQNHLLGGASIDKHHDPLTDEALNA 65 Query: 309 ARASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQ-LVDASTLK 485 A+A+DA+LLGAIGG +W + ++PE GLL +R LG + NLRP + LVD+S LK Sbjct: 66 AKAADAVLLGAIGGPEWGTSST-VRPEQGLLKLRKELGTYGNLRPCNFASESLVDSSPLK 124 Query: 486 REVAEGVDIMVVRELTGGIYFG 551 EV G D +VVRELTGGIYFG Sbjct: 125 AEVCRGTDFIVVRELTGGIYFG 146
>LEU3_ZYGBA (Q9P3Y0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 362 Score = 106 bits (264), Expect = 5e-23 Identities = 61/142 (42%), Positives = 81/142 (57%), Gaps = 2/142 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGS-KEGVELRYKEXXXXXXXXXXXXVPLPDETLAAA 311 I +LPGD +G E+ A VL A + ++ PLPDE LAAA Sbjct: 5 IVVLPGDHVGQEIAQEAIKVLEAISEVSPKAKFNFQHHLIGGSAIDATGSPLPDEALAAA 64 Query: 312 RASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQ-LVDASTLKR 488 + +DA+LLGA+GG KW ++PE GLL IR L ++ANLRP + L++ S LK Sbjct: 65 KKADAVLLGAVGGPKWGTGA--VRPEQGLLKIRKELQLYANLRPCNFASESLLELSPLKP 122 Query: 489 EVAEGVDIMVVRELTGGIYFGK 554 + A G D +VVREL GGIYFG+ Sbjct: 123 QHARGTDFIVVRELVGGIYFGQ 144
>LEU3_THEMA (Q9WZ26) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 354 Score = 106 bits (264), Expect = 5e-23 Identities = 62/144 (43%), Positives = 80/144 (55%), Gaps = 2/144 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +LPGDGIGPEVV A VL K G PLP+ET Sbjct: 3 IAVLPGDGIGPEVVREALKVLEVVEKKTGKTFEKVFGHIGGDAIDRFGEPLPEETKKICL 62 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPET-GLLNIRAGLGVFANLRPATVLPQLVDASTLKRE 491 +DAI LG++GG KWD+ +PE GLL +R L ++AN+RP V LV S LK + Sbjct: 63 EADAIFLGSVGGPKWDDLPPEKRPEIGGLLALRKMLNLYANIRPIKVYRSLVHVSPLKEK 122 Query: 492 V-AEGVDIMVVRELTGGIYFGKPR 560 V GVD++ VREL+ G+Y+G+PR Sbjct: 123 VIGSGVDLVTVRELSYGVYYGQPR 146
>LEU3_BUCUD (Q9EVE1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 105 bits (263), Expect = 7e-23 Identities = 59/143 (41%), Positives = 83/143 (58%), Gaps = 2/143 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +LPGDGIGPEV+ A +L+ + + L +E LP +TL Sbjct: 7 IAVLPGDGIGPEVMREAYKILNILKNHFSLPLETREFNIGGSAIDQEGTALPKKTLLGCE 66 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPE-TGLLNIRAGLGVFANLRPATVLPQLVDASTLKRE 491 SDAIL G++GG KWD+ + +PE LL +R +FANLRPA + +L S L+ + Sbjct: 67 NSDAILFGSVGGKKWDDLPINQRPERASLLPLRKHFNLFANLRPAKLYSELKYLSPLRSD 126 Query: 492 VAE-GVDIMVVRELTGGIYFGKP 557 + + G DI+ +RELTGG+YFGKP Sbjct: 127 IIKNGFDILCIRELTGGLYFGKP 149
>LEU3_ZYGRO (Q96WI0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 362 Score = 105 bits (263), Expect = 7e-23 Identities = 61/142 (42%), Positives = 81/142 (57%), Gaps = 2/142 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGS-KEGVELRYKEXXXXXXXXXXXXVPLPDETLAAA 311 I +LPGD G E+ A VL A + ++ PLPD+ LAAA Sbjct: 5 IVVLPGDHAGQEIAQEAIKVLEAISEVSPEAKFNFQHHLIGGAAIDATGSPLPDDALAAA 64 Query: 312 RASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQ-LVDASTLKR 488 + +DA+LLGA+GG KW ++PE GLL IR L ++ANLRP + L+D S LK Sbjct: 65 KKADAVLLGAVGGPKWGTGS--VRPEQGLLKIRKELQLYANLRPCNFASESLLDLSPLKP 122 Query: 489 EVAEGVDIMVVRELTGGIYFGK 554 + A+G D +VVREL GGIYFG+ Sbjct: 123 QHAKGTDFVVVRELVGGIYFGE 144
>LEU3_DESPS (Q6ANR1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 357 Score = 105 bits (262), Expect = 9e-23 Identities = 61/144 (42%), Positives = 79/144 (54%), Gaps = 2/144 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +L GDGIGPEV+ A VL A K G EL ++ V LP+ TL Sbjct: 4 IAVLAGDGIGPEVMEQALKVLVAVQKKFGFELSFQHADVGGAAIDSHGVALPESTLTLCA 63 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPE-TGLLNIRAGLGVFANLRPATVLPQLVDASTLKRE 491 SDAIL G++GG KW++ +PE LL +R +F N RPA V L A L+ + Sbjct: 64 ESDAILFGSVGGPKWEHLPPAEQPERAALLPLRKHFDLFCNYRPARVFKSLTAACPLRAD 123 Query: 492 -VAEGVDIMVVRELTGGIYFGKPR 560 + +G DI+ VRELT GIYFG P+ Sbjct: 124 IIGDGFDILCVRELTSGIYFGTPK 147
>LEU3_BUCUO (Q9EVI1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 364 Score = 105 bits (262), Expect = 9e-23 Identities = 60/143 (41%), Positives = 80/143 (55%), Gaps = 2/143 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +LPGDGIGPEV+ A +L + + +E + LP +TL Sbjct: 7 IAVLPGDGIGPEVMREAYKILKILKNNFLLSFEIEEFNVGGIAIDQEGLALPKKTLLGCE 66 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPE-TGLLNIRAGLGVFANLRPATVLPQLVDASTLKRE 491 SDAIL G++GG KWDN +PE LL +R +FANLRPA + +L S L+ Sbjct: 67 KSDAILFGSVGGKKWDNFPIEERPERAALLPLRKHFNLFANLRPAKIYSELKHLSPLRSN 126 Query: 492 -VAEGVDIMVVRELTGGIYFGKP 557 V +G DI+ +RELTGGIYFG+P Sbjct: 127 IVRDGFDILCIRELTGGIYFGQP 149
>LEU3_MYCGR (Q9Y897) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 365 Score = 105 bits (262), Expect = 9e-23 Identities = 62/142 (43%), Positives = 79/142 (55%), Gaps = 2/142 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAA-GSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAA 311 I + GD GPEV A A VL S V + PL DE LAAA Sbjct: 6 IVVFGGDHCGPEVTAEALKVLDVIDNSNADVHFNIQPHLLGGASIDAHGEPLTDEALAAA 65 Query: 312 RASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQ-LVDASTLKR 488 +A+DA++LGAIGG KW + ++PE G+L +R +G + NLRP + LV S LK Sbjct: 66 KAADAVILGAIGGPKWGTGK--VRPEQGILRLRKEMGTYGNLRPCFFASESLVKTSPLKE 123 Query: 489 EVAEGVDIMVVRELTGGIYFGK 554 EV GV+ +VRELTGGIYFG+ Sbjct: 124 EVCRGVNFNIVRELTGGIYFGE 145
>LEU3_SALTY (P37412) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 105 bits (261), Expect = 1e-22 Identities = 60/144 (41%), Positives = 82/144 (56%), Gaps = 2/144 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +LPGDGIGPEV+A A V+ A S+ + + PLP T+ Sbjct: 7 IAVLPGDGIGPEVMAQALKVMDAVRSRFDMRITTSHYDVGGIAIDNHGHPLPKATVEGCE 66 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETG-LLNIRAGLGVFANLRPATVLPQLVDASTLKRE 491 +DAIL G++GG KW+N +PE G LL +R +F+NLRPA + L L+ + Sbjct: 67 QADAILFGSVGGPKWENLPPESQPERGALLPLRKHFKLFSNLRPAKLYQGLEAFCPLRAD 126 Query: 492 V-AEGVDIMVVRELTGGIYFGKPR 560 + A G DI+ VRELTGGIYFG+P+ Sbjct: 127 IAANGFDILCVRELTGGIYFGQPK 150
>LEU3_SALTI (Q8Z9I1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 105 bits (261), Expect = 1e-22 Identities = 60/144 (41%), Positives = 82/144 (56%), Gaps = 2/144 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +LPGDGIGPEV+A A V+ A S+ + + PLP T+ Sbjct: 7 IAVLPGDGIGPEVMAQALKVMDAVRSRFDMRITTSRYDVGGIAIDNHGHPLPKATVEGCE 66 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETG-LLNIRAGLGVFANLRPATVLPQLVDASTLKRE 491 +DAIL G++GG KW+N +PE G LL +R +F+NLRPA + L L+ + Sbjct: 67 QADAILFGSVGGPKWENLPPESQPERGALLPLRKHFKLFSNLRPAKLYQGLEAFCPLRAD 126 Query: 492 V-AEGVDIMVVRELTGGIYFGKPR 560 + A G DI+ VRELTGGIYFG+P+ Sbjct: 127 IAANGFDILCVRELTGGIYFGQPK 150
>LEU3_SALPA (Q5PDG2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 105 bits (261), Expect = 1e-22 Identities = 60/144 (41%), Positives = 82/144 (56%), Gaps = 2/144 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +LPGDGIGPEV+A A V+ A S+ + + PLP T+ Sbjct: 7 IAVLPGDGIGPEVMAQALKVMDAVRSRFDMRITTSRYDVGGIAIDNHGHPLPKATVEGCE 66 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETG-LLNIRAGLGVFANLRPATVLPQLVDASTLKRE 491 +DAIL G++GG KW+N +PE G LL +R +F+NLRPA + L L+ + Sbjct: 67 QADAILFGSVGGPKWENLPPESQPERGALLPLRKHFKLFSNLRPAKLYQGLEAFCPLRAD 126 Query: 492 V-AEGVDIMVVRELTGGIYFGKPR 560 + A G DI+ VRELTGGIYFG+P+ Sbjct: 127 IAANGFDILCVRELTGGIYFGQPK 150
>LEU3_SALCH (Q57TE7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 105 bits (261), Expect = 1e-22 Identities = 60/144 (41%), Positives = 82/144 (56%), Gaps = 2/144 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +LPGDGIGPEV+A A V+ A S+ + + PLP T+ Sbjct: 7 IAVLPGDGIGPEVMAQALKVMDAVRSRFDMRITTSHYDVGGIAIDNHGHPLPKATVEGCE 66 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETG-LLNIRAGLGVFANLRPATVLPQLVDASTLKRE 491 +DAIL G++GG KW+N +PE G LL +R +F+NLRPA + L L+ + Sbjct: 67 QADAILFGSVGGPKWENLPPESQPERGALLPLRKHFKLFSNLRPAKLYQGLEAFCPLRAD 126 Query: 492 V-AEGVDIMVVRELTGGIYFGKPR 560 + A G DI+ VRELTGGIYFG+P+ Sbjct: 127 IAANGFDILCVRELTGGIYFGQPK 150
>LEU3_BUCAI (P56933) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 105 bits (261), Expect = 1e-22 Identities = 60/144 (41%), Positives = 83/144 (57%), Gaps = 2/144 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +L GDGIGPEV+ A +L+ + L ++ V LP TL Sbjct: 7 IAVLSGDGIGPEVMQEACKILNVLKKYFFLSLEIQKFNIGGIAIEREGVALPKTTLLGCE 66 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPE-TGLLNIRAGLGVFANLRPATVLPQLVDASTLKRE 491 SD+ILLG++GG KWDN +PE LL +R +F+NLRPA + P+L S L+ + Sbjct: 67 NSDSILLGSVGGKKWDNLPVEQRPERAALLPLRKHFNLFSNLRPAKLYPELKCLSPLRSD 126 Query: 492 VAE-GVDIMVVRELTGGIYFGKPR 560 + + G DI+ VRELTGGIYFG+P+ Sbjct: 127 IVKNGFDILCVRELTGGIYFGEPK 150
>LEU3_BUCML (Q9EVG3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 365 Score = 105 bits (261), Expect = 1e-22 Identities = 61/145 (42%), Positives = 80/145 (55%), Gaps = 3/145 (2%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +LPGDGIGPEV+ A +L + + + KE V LP +TL Sbjct: 7 IAVLPGDGIGPEVMKEAYKILKILQNYFSLHIEIKEFNIGGIALDKEGVALPKDTLLGCE 66 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPE-TGLLNIRAGLGVFANLRPATVLPQLVDASTL--K 485 SDAIL G++GG KW+N +PE LL +R +F NLRPA + +L S L K Sbjct: 67 NSDAILFGSVGGKKWNNLPIEKRPERASLLPLRKHFNLFYNLRPAKLYSELRFLSPLRSK 126 Query: 486 REVAEGVDIMVVRELTGGIYFGKPR 560 + G DI+ +RELTGGIYFG+PR Sbjct: 127 TXIKNGFDILCIRELTGGIYFGEPR 151
>LEU3_BUCUE (Q9EVH5) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 364 Score = 103 bits (256), Expect = 4e-22 Identities = 61/143 (42%), Positives = 78/143 (54%), Gaps = 2/143 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +LPGDGIGPEV+ A +L+ + L KE + LP TL Sbjct: 7 IAVLPGDGIGPEVMQEAYKILNILKDHFLLPLEMKEFNIGGIAIDQEGIALPKNTLLGCE 66 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPE-TGLLNIRAGLGVFANLRPATVLPQLVDASTLKRE 491 SDAIL G++GG KWD +PE LL +R +F+NLRPA + L S L+ Sbjct: 67 NSDAILFGSVGGKKWDYLSIDKRPERAALLPLRKHFNLFSNLRPAKLYADLKYLSPLRSN 126 Query: 492 -VAEGVDIMVVRELTGGIYFGKP 557 + +G DI+ VRELTGGIYFGKP Sbjct: 127 IIKDGFDILCVRELTGGIYFGKP 149
>LEU3_PHOLL (Q7N128) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 102 bits (254), Expect = 7e-22 Identities = 59/144 (40%), Positives = 84/144 (58%), Gaps = 2/144 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +LPGDGIGPEV+A A +L A + + + E LP +T+A Sbjct: 7 IAVLPGDGIGPEVMAQAYKILDAIRKRFNICITTSEYDVGGIAIDRHGCSLPAKTVAGCE 66 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETG-LLNIRAGLGVFANLRPATVLPQLVDASTLKRE 491 +DAIL G++GG KW++ +PE G LL +R +F+NLRPA + L L+ + Sbjct: 67 QADAILFGSVGGPKWEHLPPAEQPERGALLPLRKHFKLFSNLRPARLYAGLEVFCPLRND 126 Query: 492 V-AEGVDIMVVRELTGGIYFGKPR 560 + A+G DI+ VRELTGGIYFG+P+ Sbjct: 127 IAAKGFDILCVRELTGGIYFGQPK 150
>LEU3_SHISS (Q3Z5T7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 102 bits (253), Expect = 1e-21 Identities = 57/144 (39%), Positives = 82/144 (56%), Gaps = 2/144 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +LPGDGIGPEV+ A VL+A ++ + + PLP T+ Sbjct: 7 IAVLPGDGIGPEVMTQALKVLNAVRNRFAMRITTSHYDVGGAAIDNHGQPLPPATVEGCE 66 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETG-LLNIRAGLGVFANLRPATVLPQLVDASTLKRE 491 +DA+L G++GG KW++ +PE G LL +R +F+NLRPA + L L+ + Sbjct: 67 QADAVLFGSVGGPKWEHLPPDQQPERGALLPLRKRFKLFSNLRPAKLYQGLEAFCPLRAD 126 Query: 492 V-AEGVDIMVVRELTGGIYFGKPR 560 + A G DI+ VRELTGGIYFG+P+ Sbjct: 127 IAANGFDILCVRELTGGIYFGQPK 150
>LEU3_SHIBS (Q326G2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 101 bits (252), Expect = 1e-21 Identities = 57/144 (39%), Positives = 81/144 (56%), Gaps = 2/144 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +LPGDGIGPEV+ A VL A ++ + + PLP T+ Sbjct: 7 IAVLPGDGIGPEVMTQALKVLDAVRNRFAMRITTSHYDVGGAAIDNHGQPLPPATVEGCE 66 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETG-LLNIRAGLGVFANLRPATVLPQLVDASTLKRE 491 +DA+L G++GG KW++ +PE G LL +R +F+NLRPA + L L+ + Sbjct: 67 QADAVLFGSVGGPKWEHLPPDQQPERGALLPLRKHFKLFSNLRPAKLYQGLEAFCPLRAD 126 Query: 492 V-AEGVDIMVVRELTGGIYFGKPR 560 + A G DI+ VRELTGGIYFG+P+ Sbjct: 127 IAANGFDILCVRELTGGIYFGQPK 150
>LEU3_ECOLI (P30125) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 362 Score = 101 bits (252), Expect = 1e-21 Identities = 57/144 (39%), Positives = 81/144 (56%), Gaps = 2/144 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +LPGDGIGPEV+ A VL A ++ + + PLP T+ Sbjct: 6 IAVLPGDGIGPEVMTQALKVLDAVRNRFAMRITTSHYDVGGAAIDNHGQPLPPATVEGCE 65 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETG-LLNIRAGLGVFANLRPATVLPQLVDASTLKRE 491 +DA+L G++GG KW++ +PE G LL +R +F+NLRPA + L L+ + Sbjct: 66 QADAVLFGSVGGPKWEHLPPDQQPERGALLPLRKHFKLFSNLRPAKLYQGLEAFCPLRAD 125 Query: 492 V-AEGVDIMVVRELTGGIYFGKPR 560 + A G DI+ VRELTGGIYFG+P+ Sbjct: 126 IAANGFDILCVRELTGGIYFGQPK 149
>LEU3_ECOL6 (Q8FL76) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 362 Score = 101 bits (252), Expect = 1e-21 Identities = 57/144 (39%), Positives = 81/144 (56%), Gaps = 2/144 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +LPGDGIGPEV+ A VL A ++ + + PLP T+ Sbjct: 6 IAVLPGDGIGPEVMTQALKVLDAVRNRFAMRITTSHYDVGGAAIDNHGQPLPPATVEGCE 65 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETG-LLNIRAGLGVFANLRPATVLPQLVDASTLKRE 491 +DA+L G++GG KW++ +PE G LL +R +F+NLRPA + L L+ + Sbjct: 66 QADAVLFGSVGGPKWEHLPPDQQPERGALLPLRKHFKLFSNLRPAKLYQGLEAFCPLRAD 125 Query: 492 V-AEGVDIMVVRELTGGIYFGKPR 560 + A G DI+ VRELTGGIYFG+P+ Sbjct: 126 IAANGFDILCVRELTGGIYFGQPK 149
>LEU3_ECO57 (Q8X9Z9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 362 Score = 101 bits (252), Expect = 1e-21 Identities = 57/144 (39%), Positives = 81/144 (56%), Gaps = 2/144 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +LPGDGIGPEV+ A VL A ++ + + PLP T+ Sbjct: 6 IAVLPGDGIGPEVMTQALKVLDAVRNRFAMRITTSHYDVGGAAIDNHGQPLPPATVEGCE 65 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETG-LLNIRAGLGVFANLRPATVLPQLVDASTLKRE 491 +DA+L G++GG KW++ +PE G LL +R +F+NLRPA + L L+ + Sbjct: 66 QADAVLFGSVGGPKWEHLPPDQQPERGALLPLRKHFKLFSNLRPAKLYQGLEAFCPLRAD 125 Query: 492 V-AEGVDIMVVRELTGGIYFGKPR 560 + A G DI+ VRELTGGIYFG+P+ Sbjct: 126 IAANGFDILCVRELTGGIYFGQPK 149
>LEU3_SHIFL (Q83SP1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 362 Score = 101 bits (251), Expect = 2e-21 Identities = 57/144 (39%), Positives = 81/144 (56%), Gaps = 2/144 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +LPGDGIGPEV+ A VL+A ++ + + PLP T+ Sbjct: 6 IAVLPGDGIGPEVMTQALKVLNAVRNRFAMRITTSHYDVGGAAIDNHGQPLPPATVEGCE 65 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETG-LLNIRAGLGVFANLRPATVLPQLVDASTLKRE 491 +DA+L G++GG KW++ +PE G LL +R +F+NLRPA + L L+ + Sbjct: 66 QADAVLFGSVGGPKWEHLPPDQQPERGALLPLRKHFKLFSNLRPAKLYQGLEAFCPLRAD 125 Query: 492 V-AEGVDIMVVRELTGGIYFGKPR 560 + A G DI VRELTGGIYFG+P+ Sbjct: 126 IAANGFDIQCVRELTGGIYFGQPK 149
>LEU3_SHIDS (Q32K21) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 100 bits (250), Expect = 2e-21 Identities = 57/144 (39%), Positives = 80/144 (55%), Gaps = 2/144 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I LPGDGIGPEV+ A VL A ++ + + PLP T+ Sbjct: 7 IAALPGDGIGPEVMTQALKVLDAVRNRFAMRITTSHYDVGGAAIDNHGQPLPPATVEGCE 66 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETG-LLNIRAGLGVFANLRPATVLPQLVDASTLKRE 491 +DA+L G++GG KW++ +PE G LL +R +F+NLRPA + L L+ + Sbjct: 67 QADAVLFGSVGGPKWEHLPPDQQPERGALLPLRKHFKLFSNLRPAKLYQGLEAFCPLRAD 126 Query: 492 V-AEGVDIMVVRELTGGIYFGKPR 560 + A G DI+ VRELTGGIYFG+P+ Sbjct: 127 IAANGFDILCVRELTGGIYFGQPK 150
>LEU3_YARLI (P18120) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 405 Score = 100 bits (248), Expect = 4e-21 Identities = 57/146 (39%), Positives = 81/146 (55%), Gaps = 6/146 (4%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I LL GD GPEV+A A VL + G E +++ P+ D TL R Sbjct: 15 IVLLGGDFCGPEVIAEAVKVLKSVAEASGTEFVFEDRLIGGAAIEKEGEPITDATLDICR 74 Query: 315 ASDAILLGAIGG-----YKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVL-PQLVDAS 476 +D+I+LGA+GG + + ++PE GLL +R L ++ANLRP +L P+L D S Sbjct: 75 KADSIMLGAVGGAANTVWTTPDGRTDVRPEQGLLKLRKDLNLYANLRPCQLLSPKLADLS 134 Query: 477 TLKREVAEGVDIMVVRELTGGIYFGK 554 ++ EG D ++VREL GGIYFG+ Sbjct: 135 PIRN--VEGTDFIIVRELVGGIYFGE 158
>LEU3_CEPAC (Q12545) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 380 Score = 98.2 bits (243), Expect = 1e-20 Identities = 59/144 (40%), Positives = 79/144 (54%), Gaps = 2/144 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGS-KEGVELRYKEXXXXXXXXXXXXVPLPDETLAAA 311 I +LPGD IGPE++A A VL+ + + + VP+ L AA Sbjct: 7 ILVLPGDHIGPEIMAEAIKVLTTIETHRPNLHFNLTTDLVGGTSIDTHGVPITQSVLDAA 66 Query: 312 RASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVL-PQLVDASTLKR 488 +ASDA+L G+IGG +W H PE+GLL +R L FANLRP L P LV AS ++ Sbjct: 67 KASDAVLFGSIGGPEWAG--VHPTPESGLLQLRQHLDAFANLRPCEFLVPSLVGASPIRE 124 Query: 489 EVAEGVDIMVVRELTGGIYFGKPR 560 V +G +VVRE GG YFG+ + Sbjct: 125 HVVKGTRFIVVRENCGGAYFGEKK 148
>LEU3_BUCPS (P59027) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 98.2 bits (243), Expect = 1e-20 Identities = 63/146 (43%), Positives = 85/146 (58%), Gaps = 4/146 (2%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYK--EXXXXXXXXXXXXVPLPDETLAA 308 + +LPGDGIGPE++ KD L+ KE +L+ E LP ETL Sbjct: 7 LAILPGDGIGPELLQ--KD-LNFKVLKEQYKLKINTTEYDIGGIAIDKYGKALPKETLDG 63 Query: 309 ARASDAILLGAIGGYKWDNNEKHLKPE-TGLLNIRAGLGVFANLRPATVLPQLVDASTLK 485 + SD+IL G++GG KW + +PE LL IR +F+NLRPA + L S L+ Sbjct: 64 CKESDSILFGSVGGPKWQHLPPDQQPERAALLPIRKYFNLFSNLRPAKLYSTLNHLSPLR 123 Query: 486 REVAE-GVDIMVVRELTGGIYFGKPR 560 R+++E G DI+ VRELTGGIYFGKP+ Sbjct: 124 RDISEKGFDILCVRELTGGIYFGKPK 149
>LEU3_BUCUN (Q9EVI7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 364 Score = 97.8 bits (242), Expect = 2e-20 Identities = 59/144 (40%), Positives = 79/144 (54%), Gaps = 3/144 (2%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +LPGDGIGPEV+ A +L+ + L +E V LP +TL Sbjct: 7 IAVLPGDGIGPEVMREAYKILNILKYHFSLPLEIEEFDVGGSAIDKEGVALPKKTLLGCE 66 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPE-TGLLNIRAGLGVFANLRPATVLPQLVDASTLK-- 485 +DAIL G++GG KWD+ +PE LL +R +FANLRPA + +L S L Sbjct: 67 NADAILFGSVGGRKWDSLPIDQRPERASLLPLRKHFNLFANLRPAQLYSELKYLSPLAFL 126 Query: 486 REVAEGVDIMVVRELTGGIYFGKP 557 + G +I+ VRELTGGIYFG+P Sbjct: 127 IVIKNGFNILCVRELTGGIYFGQP 150
>LEU3_BLOPB (Q493R1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 366 Score = 95.9 bits (237), Expect = 7e-20 Identities = 55/144 (38%), Positives = 76/144 (52%), Gaps = 2/144 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +LPGDGIGPE +L+ + + + E P P TL Sbjct: 7 IAVLPGDGIGPETTRQVYKILNVIKKQFQINIVTTEHKIGGDAINSEGTPFPKSTLKYCE 66 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETG-LLNIRAGLGVFANLRPATVLPQLVDASTLK-R 488 S+AIL GA+GG +W + + PE G LL +R +FANLRP + +L + S L Sbjct: 67 QSNAILFGAVGGPQWTHLKGSESPEQGALLALRKHFNLFANLRPIYLADELKELSPLNIN 126 Query: 489 EVAEGVDIMVVRELTGGIYFGKPR 560 + G+DI+ VRELTGGIYFG+P+ Sbjct: 127 MIPNGIDIIFVRELTGGIYFGQPK 150
>LEU3B_ASPNG (P87257) 3-isopropylmalate dehydrogenase B (EC 1.1.1.85) (Beta-IPM| dehydrogenase B) (IMDH B) (3-IPM-DH B) Length = 371 Score = 91.3 bits (225), Expect = 2e-18 Identities = 60/145 (41%), Positives = 80/145 (55%), Gaps = 5/145 (3%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +LPGDGIGPEV+A A VL S ++ +E + AA Sbjct: 9 ILVLPGDGIGPEVMAEAIKVLRTFNSSS-MQFHLQEELIGGISIDTHGHSVTQPVKDAAV 67 Query: 315 ASDAILLGAIGGYKWDNNEKHLK-PETGLLNIRAGLGVFANLRPATV-LPQLV---DAST 479 A+DA+L A+GG K D+ + L PE GLL +R + ++ANLRP +V +P D S Sbjct: 68 AADAVLFAAVGGSKVDHIRRGLDGPEGGLLQVRKAMDIYANLRPCSVDVPSREIARDFSP 127 Query: 480 LKREVAEGVDIMVVRELTGGIYFGK 554 ++EV EGVD +VVRE GG YFGK Sbjct: 128 FRQEVIEGVDFVVVRENCGGAYFGK 152
>LEU3_BUCUS (Q9EVI4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 81.6 bits (200), Expect = 1e-15 Identities = 51/143 (35%), Positives = 71/143 (49%), Gaps = 2/143 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +LPGDGIGPEV+ A +L+ + + + +E V LP TL Sbjct: 7 IAVLPGDGIGPEVMREAYKILNILKNYFSLPIETREFNVGGAAIDQDGVALPKTTLLGCE 66 Query: 315 ASDAILLGA-IGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKRE 491 SDAIL G+ LL +R +F NLRPA + +L+ S L+ + Sbjct: 67 NSDAILFGSXXXXXXXXXXXXXXXXXXXLLPLRKHFNLFGNLRPAQLYSELIHLSPLRSD 126 Query: 492 VA-EGVDIMVVRELTGGIYFGKP 557 + G +I+ +RELTGGIYFGKP Sbjct: 127 IINNGFNILCIRELTGGIYFGKP 149
>LEU3_AZOVI (P96197) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 360 Score = 79.3 bits (194), Expect = 7e-15 Identities = 58/144 (40%), Positives = 68/144 (47%), Gaps = 2/144 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKE--GVELRYKEXXXXXXXXXXXXVPLPDETLAA 308 I +LPGDGIGPE++A A VL A K G L Y E VPL DETL Sbjct: 5 ILVLPGDGIGPEIMAEAVKVLQLANEKYQLGFVLGYDELGGAAVDKYG--VPLADETLER 62 Query: 309 ARASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKR 488 AR + H P G P + PQL +ASTL+ Sbjct: 63 ARRRCHPARRRRRSEMGRHRPGH-PPGARPAENPFATGPVRQPAPGVLYPQLAEASTLRP 121 Query: 489 EVAEGVDIMVVRELTGGIYFGKPR 560 EV G+DI++VRELTGGIYFG PR Sbjct: 122 EVVAGLDILIVRELTGGIYFGAPR 145
>LEU3_LEIXX (Q6AEP6) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 357 Score = 79.0 bits (193), Expect = 9e-15 Identities = 53/140 (37%), Positives = 67/140 (47%), Gaps = 1/140 (0%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 + ++PGDGIGPEV+A A L A + G+ + L D+ LAA R Sbjct: 7 LVVIPGDGIGPEVIAEAVKALDAVTAGSGLAFQKTYFSLGADRYLATGDVLTDDDLAAIR 66 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETG-LLNIRAGLGVFANLRPATVLPQLVDASTLKRE 491 DAILLGA+GG D E G LL +R L + NLRP T+ P + E Sbjct: 67 GHDAILLGAVGGRPGDPRLAGANVERGLLLRLRFSLDHYVNLRPTTLFPGIASPLAAPGE 126 Query: 492 VAEGVDIMVVRELTGGIYFG 551 VD +VVRE T G Y G Sbjct: 127 ----VDFVVVREGTEGQYVG 142
>LEU3_THEFY (Q47SB4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 354 Score = 70.9 bits (172), Expect = 2e-12 Identities = 52/140 (37%), Positives = 66/140 (47%), Gaps = 1/140 (0%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 + ++PGDGIGPEVVA VLSA + G+ L E LPD R Sbjct: 8 LAVIPGDGIGPEVVAEGLKVLSAVAPRHGLTLDTTEYELGAQRWHATGEVLPDAVEEELR 67 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETG-LLNIRAGLGVFANLRPATVLPQLVDASTLKRE 491 DAILLGA+G D E G LL +R + NLRP + P + + L Sbjct: 68 QHDAILLGAVG----DPTVPSGVLERGLLLRLRFNFSHYVNLRPVRLYPGV--TTPLAGV 121 Query: 492 VAEGVDIMVVRELTGGIYFG 551 E +D++VVRE T G Y G Sbjct: 122 APEDIDMLVVREGTEGPYAG 141
>LEU3_ARCFU (O29627) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 326 Score = 64.7 bits (156), Expect = 2e-10 Identities = 48/139 (34%), Positives = 64/139 (46%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I ++PGDGIG EV+ A +L K + Y LPDETL A R Sbjct: 4 IVVIPGDGIGKEVMEAAMLILE----KLDLPFEYSYYDAGDEALEKYGKALPDETLEACR 59 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 SDA+L GA G D ++ +R LG FAN+RPA + + + Sbjct: 60 KSDAVLFGAAGETAAD----------VIVRLRRELGTFANVRPAKAIEGI-------ECL 102 Query: 495 AEGVDIMVVRELTGGIYFG 551 G+DI+VVRE T +Y G Sbjct: 103 YPGLDIVVVRENTECLYMG 121
>LEU3_STRCO (O86504) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 347 Score = 64.3 bits (155), Expect = 2e-10 Identities = 54/140 (38%), Positives = 68/140 (48%), Gaps = 1/140 (0%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 + ++PGDGIG EVVA VLSA + V+L KE L D L A + Sbjct: 7 LAVIPGDGIGQEVVAEGLKVLSAV-LPQDVKLETKEFDFGARRYHATGETLTDADLDALK 65 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETG-LLNIRAGLGVFANLRPATVLPQLVDASTLKRE 491 A DAILLGAIG D + E G LL +R NLRP+ +LP + + E Sbjct: 66 AHDAILLGAIG----DPSVPSGVLERGFLLKLRFAFDHHVNLRPSKLLPGVATPLAGQPE 121 Query: 492 VAEGVDIMVVRELTGGIYFG 551 +D +VVRE T G Y G Sbjct: 122 ----IDFVVVREGTEGPYTG 137
>LEU3_STRAW (Q82JN6) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 347 Score = 62.8 bits (151), Expect = 6e-10 Identities = 54/140 (38%), Positives = 68/140 (48%), Gaps = 1/140 (0%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 + ++PGDGIG EVVA VLSAA + V+L KE L D L A + Sbjct: 7 LAVIPGDGIGQEVVAQGLKVLSAALPSD-VKLETKEFDFGARRYHATGETLTDADLDALK 65 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETG-LLNIRAGLGVFANLRPATVLPQLVDASTLKRE 491 DAILLGAIG D + E G LL +R NLRP+ +LP + + E Sbjct: 66 QHDAILLGAIG----DPSVPSGVLERGFLLKLRFAFDHHVNLRPSKLLPGVETPLAGQPE 121 Query: 492 VAEGVDIMVVRELTGGIYFG 551 +D +VVRE T G Y G Sbjct: 122 ----IDFVVVREGTEGPYTG 137
>LEU3_MYCTU (P95313) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 336 Score = 58.9 bits (141), Expect = 9e-09 Identities = 55/140 (39%), Positives = 67/140 (47%), Gaps = 1/140 (0%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 + ++ GDGIGPEV A A VL A GV+ + LPD +A R Sbjct: 3 LAIIAGDGIGPEVTAEAVKVLDAV--VPGVQKTSYDLGARRFHATGEV--LPDSVVAELR 58 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETG-LLNIRAGLGVFANLRPATVLPQLVDASTLKRE 491 DAILLGAIG D + E G LL +R L NLRPA + P + AS L Sbjct: 59 NHDAILLGAIG----DPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGV--ASPLSGN 112 Query: 492 VAEGVDIMVVRELTGGIYFG 551 G+D +VVRE T G Y G Sbjct: 113 --PGIDFVVVREGTEGPYTG 130
>LEU3_MYCBO (P94929) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 336 Score = 58.9 bits (141), Expect = 9e-09 Identities = 55/140 (39%), Positives = 67/140 (47%), Gaps = 1/140 (0%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 + ++ GDGIGPEV A A VL A GV+ + LPD +A R Sbjct: 3 LAIIAGDGIGPEVTAEAVKVLDAV--VPGVQKTSYDLGARRFHATGEV--LPDSVVAELR 58 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETG-LLNIRAGLGVFANLRPATVLPQLVDASTLKRE 491 DAILLGAIG D + E G LL +R L NLRPA + P + AS L Sbjct: 59 NHDAILLGAIG----DPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGV--ASPLSGN 112 Query: 492 VAEGVDIMVVRELTGGIYFG 551 G+D +VVRE T G Y G Sbjct: 113 --PGIDFVVVREGTEGPYTG 130
>LYS12_YEAST (P40495) Homoisocitrate dehydrogenase, mitochondrial precursor (EC| 1.1.1.87) Length = 371 Score = 58.5 bits (140), Expect = 1e-08 Identities = 39/137 (28%), Positives = 63/137 (45%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I L+PGDGIG EV+ K VL SK G+ + + LPDET+ + Sbjct: 26 IGLIPGDGIGKEVIPAGKQVLENLNSKHGLSFNFIDLYAGFQTFQETGKALPDETVKVLK 85 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 GA+ G K + ++ +R +G+FAN+RP +++ E Sbjct: 86 EQ---CQGALFGAVQSPTTKVEGYSSPIVALRREMGLFANVRP---------VKSVEGEK 133 Query: 495 AEGVDIMVVRELTGGIY 545 + +D+++VRE T +Y Sbjct: 134 GKPIDMVIVRENTEDLY 150
>LEU3_BIFLO (Q8G500) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 343 Score = 58.2 bits (139), Expect = 2e-08 Identities = 50/141 (35%), Positives = 67/141 (47%), Gaps = 2/141 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGV-ELRYKEXXXXXXXXXXXXVPLPDETLAAA 311 I ++PGDGIG EV A+ L A EGV + Y+ LP++ Sbjct: 7 IAVIPGDGIGKEVTPWAQKALEKAA--EGVADFEYENFDLGAERYLRDGAILPEDEEERI 64 Query: 312 RASDAILLGAIGGYKWDNNEKHLKPETG-LLNIRAGLGVFANLRPATVLPQLVDASTLKR 488 +A+DAILLGA+G D K E G LL +R L + NLRP+ +L T Sbjct: 65 KANDAILLGAVG----DPRIKAGILERGLLLKLRFDLDQYVNLRPS----KLYKGVTSPL 116 Query: 489 EVAEGVDIMVVRELTGGIYFG 551 +D +VVRE T G+Y G Sbjct: 117 ANPGDIDFVVVREGTEGLYCG 137
>LEU3_NOCFA (Q5YRX2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 335 Score = 55.1 bits (131), Expect = 1e-07 Identities = 53/140 (37%), Positives = 62/140 (44%), Gaps = 1/140 (0%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 + ++PGDGIGPEV+A A VL GVE E LPD L R Sbjct: 3 LAVIPGDGIGPEVIAEALKVLDVV--VPGVE--KTEYDLGAKRYHATGEILPDSVLPELR 58 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETG-LLNIRAGLGVFANLRPATVLPQLVDASTLKRE 491 DAILLGAIG D + E G LL R L NLRP+ +L Sbjct: 59 EHDAILLGAIG----DPSVPSGVLERGLLLRTRFELDHHVNLRPS----RLFTGVRSPLA 110 Query: 492 VAEGVDIMVVRELTGGIYFG 551 A +D +VVRE T G Y G Sbjct: 111 GAPDIDFVVVREGTEGPYTG 130
>LEU3_MYCLE (O33117) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 336 Score = 54.7 bits (130), Expect = 2e-07 Identities = 50/140 (35%), Positives = 65/140 (46%), Gaps = 1/140 (0%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 + ++ GDGIGPEVVA A +L GV+ + LP+ LA R Sbjct: 3 LAIIGGDGIGPEVVAQAVKILDVV--LPGVQKTTYDLGARRYHTTGEL--LPESVLAELR 58 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETG-LLNIRAGLGVFANLRPATVLPQLVDASTLKRE 491 DAILLGA+G D + E G LL +R L NLRPA + P + K + Sbjct: 59 EHDAILLGAVG----DPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVNSLLAGKPD 114 Query: 492 VAEGVDIMVVRELTGGIYFG 551 +D +VVRE T G Y G Sbjct: 115 ----IDFVVVREGTEGPYTG 130
>TTUC_PSEPU (Q51945) Tartrate dehydrogenase/decarboxylase (EC 1.1.1.93) (EC| 4.1.1.73) (TDH) (D-malate dehydrogenase [decarboxylating]) (EC 1.1.1.83) Length = 364 Score = 53.9 bits (128), Expect = 3e-07 Identities = 44/139 (31%), Positives = 61/139 (43%), Gaps = 2/139 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXX-XXXXXXXXXXVPLPDETLAAA 311 I +PGDGIG EV+ VL AA K G+ L + +PD+ Sbjct: 7 IAAIPGDGIGLEVLPEGIRVLEAAALKHGLALEFDTFEWASCDYYLQHGKMMPDDWAEQL 66 Query: 312 RASDAILLGAIGGYKW-DNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKR 488 + DAI GA+ W D H+ LL R + N+RP + P V + R Sbjct: 67 KQYDAIYFGAV---DWPDKVPDHISLWGSLLKFRREFDQYVNIRPVRLFPG-VPCALANR 122 Query: 489 EVAEGVDIMVVRELTGGIY 545 +V + +D +VVRE T G Y Sbjct: 123 KVGD-IDFVVVRENTEGEY 140
>LEU3_SULTO (P50455) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 336 Score = 53.9 bits (128), Expect = 3e-07 Identities = 39/139 (28%), Positives = 63/139 (45%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 + L+ GDGIGPE+V+ +K +L+ + + Y E LP ++L Sbjct: 4 VALIQGDGIGPEIVSKSKRILAKINELYSLPIEYIEVEAGDRALARYGEALPKDSLKIID 63 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 +D IL G +G D ++ +R ++AN+RPA +P +D Sbjct: 64 KADIILKGPVGESAAD----------VVVKLRQIYDMYANIRPAKSIPG-IDTK------ 106 Query: 495 AEGVDIMVVRELTGGIYFG 551 VDI++VRE T +Y G Sbjct: 107 YGNVDILIVRENTEDLYKG 125
>LEU3_MYCPA (Q73VI1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 336 Score = 53.5 bits (127), Expect = 4e-07 Identities = 53/140 (37%), Positives = 65/140 (46%), Gaps = 1/140 (0%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 + ++ GDGIGPEV A A VL A GV+ E LPD + R Sbjct: 3 LAVIGGDGIGPEVTAEALKVLDAV--LPGVDKT--EYDLGARRYHATGELLPDSVIDELR 58 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETG-LLNIRAGLGVFANLRPATVLPQLVDASTLKRE 491 A DAILLGAIG D + E G LL +R L NLRP + P + +S L Sbjct: 59 AHDAILLGAIG----DPSVPSGVLERGLLLRLRFELDHHINLRPGRLYPGV--SSPLAGN 112 Query: 492 VAEGVDIMVVRELTGGIYFG 551 +D +VVRE T G Y G Sbjct: 113 --PDIDFVVVREGTEGPYTG 130
>AKSF_METJA (Q58991) Threo-isocitrate dehydrogenase [NAD] (EC 1.1.1.-)| Length = 347 Score = 53.5 bits (127), Expect = 4e-07 Identities = 42/154 (27%), Positives = 73/154 (47%), Gaps = 12/154 (7%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKE------GVELRYKEXXXXXXXXXXXXVPLPDE 296 + ++ GDGIG EV+ A +L+ G E G+E K LP++ Sbjct: 4 VCVIEGDGIGKEVIPEAIKILNELGEFEIIKGEAGLECLKKYGNA-----------LPED 52 Query: 297 TLAAARASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPAT------VLP 458 T+ A+ +D IL GAI K + + P ++ +R ++AN+RP ++ Sbjct: 53 TIEKAKEADIILFGAITSPKPGEVQNYKSP---IITLRKMFHLYANVRPINNFGIGQLIG 109 Query: 459 QLVDASTLKREVAEGVDIMVVRELTGGIYFGKPR 560 ++ D L A+ +DI+++RE T +Y G+ R Sbjct: 110 KIADYEFLN---AKNIDIVIIRENTEDLYVGRER 140
>LEU3_SULSO (Q9UXB2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 336 Score = 53.1 bits (126), Expect = 5e-07 Identities = 37/139 (26%), Positives = 62/139 (44%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 + ++PGDGIGPE+ +K +++ K +++ E LP TL Sbjct: 5 VAVIPGDGIGPELYEGSKRIIAKLIEKYNLDIDLIEVEAGDVALNKYGEALPRHTLDVIE 64 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 +D IL G +G D ++ +R ++AN+RPA LP + + Sbjct: 65 KADMILKGPVGETAMD----------VVVKLRQMYDMYANIRPAKSLPNV-------QSK 107 Query: 495 AEGVDIMVVRELTGGIYFG 551 VD+++VRE T +Y G Sbjct: 108 YPNVDLVIVRENTEDLYKG 126
>LEU3_CORGL (P94631) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 340 Score = 52.8 bits (125), Expect = 7e-07 Identities = 47/139 (33%), Positives = 62/139 (44%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 + ++ GDGIGPEV A A VL+A ++ + L DE LA+ R Sbjct: 3 LAVIGGDGIGPEVTAEALKVLNAVRD----DIETTDYDLGARRYLKNGELLTDEDLASLR 58 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 DAILLGAIG + + LL +R L NLRP+ +L D Sbjct: 59 EHDAILLGAIGAP--GSVPPGILERGLLLKMRFALDHHVNLRPS----KLYDGVESPLRN 112 Query: 495 AEGVDIMVVRELTGGIYFG 551 +D +VVRE T G Y G Sbjct: 113 PGKIDFVVVREGTEGAYTG 131
>LEU3_CORDI (Q6NHM7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 339 Score = 52.8 bits (125), Expect = 7e-07 Identities = 48/143 (33%), Positives = 64/143 (44%), Gaps = 4/143 (2%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 + ++ GDGIGPEV A A VL+A ++ + L D L + R Sbjct: 3 LAVIGGDGIGPEVTAEALKVLNAVRD----DIEVTDYDLGARRYLRNGELLADADLVSLR 58 Query: 315 ASDAILLGAIGGYKWDNNEKHLKP---ETG-LLNIRAGLGVFANLRPATVLPQLVDASTL 482 DAILLGAIG + P E G LL +R L NLRP+ + P +T Sbjct: 59 EHDAILLGAIGA------PGEVPPGVLERGLLLKMRFALDHHVNLRPSKLYP----TATS 108 Query: 483 KREVAEGVDIMVVRELTGGIYFG 551 +D +VVRE T G+Y G Sbjct: 109 PLANPGDIDFVVVREGTEGLYCG 131
>TTUC2_AGRVI (P70787) Probable tartrate dehydrogenase/decarboxylase ttuC (EC| 1.1.1.93) (EC 4.1.1.73) (TDH) (D-malate dehydrogenase [decarboxylating]) (EC 1.1.1.83) Length = 364 Score = 51.6 bits (122), Expect = 1e-06 Identities = 42/140 (30%), Positives = 61/140 (43%), Gaps = 1/140 (0%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEG-VELRYKEXXXXXXXXXXXXVPLPDETLAAA 311 I +P DGIGPEV+A VL A + G + + V +P + L Sbjct: 6 IAAIPADGIGPEVIAAGLQVLEALEKRSGDFSIHTETFDWGSDYYKKNGVMMPADGLEQL 65 Query: 312 RASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKRE 491 + DAI GA+G + H+ L I G +AN+RP VLP + L+ Sbjct: 66 KKFDAIFFGAVGA---PDVPDHITLWGLRLPICQGFDQYANVRPTKVLPGI--TPPLRNC 120 Query: 492 VAEGVDIMVVRELTGGIYFG 551 +D ++VRE + G Y G Sbjct: 121 GPGDLDWVIVRENSEGEYSG 140
>TTUC_ECOLI (P76251) Probable tartrate dehydrogenase/decarboxylase (EC| 1.1.1.93) (EC 4.1.1.73) (TDH) (D-malate dehydrogenase [decarboxylating]) (EC 1.1.1.83) Length = 361 Score = 51.6 bits (122), Expect = 1e-06 Identities = 43/139 (30%), Positives = 58/139 (41%), Gaps = 2/139 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXX-XXXXXXXXXXVPLPDETLAAA 311 I +PGDGIG EV+ VL AA + G L +++ +PD+ Sbjct: 7 IAAIPGDGIGKEVLPEGIRVLQAAAERWGFALSFEQMEWASCEYYSHHGKMMPDDWHEQL 66 Query: 312 RASDAILLGAIGGYKW-DNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKR 488 DAI GA+G W D H+ LL R + NLRP + P + L Sbjct: 67 SRFDAIYFGAVG---WPDTVPDHISLWGSLLKFRREFDQYVNLRPVRLFPGV--PCPLAG 121 Query: 489 EVAEGVDIMVVRELTGGIY 545 + +D VVRE T G Y Sbjct: 122 KQPGDIDFYVVRENTEGEY 140
>TTUC4_AGRVI (P70792) Probable tartrate dehydrogenase/decarboxylase ttuC' (EC| 1.1.1.93) (EC 4.1.1.73) (TDH) (D-malate dehydrogenase [decarboxylating]) (EC 1.1.1.83) Length = 358 Score = 51.6 bits (122), Expect = 1e-06 Identities = 42/140 (30%), Positives = 61/140 (43%), Gaps = 1/140 (0%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEG-VELRYKEXXXXXXXXXXXXVPLPDETLAAA 311 I +P DGIGPEV+A VL A + G + + V +P + L Sbjct: 6 IAAIPADGIGPEVIAAGLQVLEALEKRSGDFSIHTETFDWGSDYYKKNGVMMPADGLEQL 65 Query: 312 RASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKRE 491 + DAI GA+G + H+ L I G +AN+RP VLP + L+ Sbjct: 66 KKFDAIFFGAVGA---PDVPDHITLWGLRLPICQGFDQYANVRPTKVLPGI--TPPLRNC 120 Query: 492 VAEGVDIMVVRELTGGIYFG 551 +D ++VRE + G Y G Sbjct: 121 GPGDLDWVIVRENSEGEYSG 140
>TTUC1_AGRVI (Q44471) Probable tartrate dehydrogenase/decarboxylase ttuC (EC| 1.1.1.93) (EC 4.1.1.73) (TDH) (D-malate dehydrogenase [decarboxylating]) (EC 1.1.1.83) Length = 364 Score = 51.2 bits (121), Expect = 2e-06 Identities = 41/140 (29%), Positives = 62/140 (44%), Gaps = 1/140 (0%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEG-VELRYKEXXXXXXXXXXXXVPLPDETLAAA 311 I +P DGIGPEV+A VL A + G ++ + V +P + L Sbjct: 6 IAAIPADGIGPEVIAAGLQVLEALEQRSGDFKIHTETFDWGSDYYKKHGVMMPADGLDKL 65 Query: 312 RASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKRE 491 + DAI GA+G + H+ L I G +AN+RP +LP + L+ Sbjct: 66 KKFDAIFFGAVGA---PDVPDHITLWGLRLPICQGFDQYANVRPTKILPGI--TPPLRNC 120 Query: 492 VAEGVDIMVVRELTGGIYFG 551 +D ++VRE + G Y G Sbjct: 121 GPGDLDWVIVRENSEGEYSG 140
>TTUC5_AGRVI (O34295) Probable tartrate dehydrogenase/decarboxylase ttuC' (EC| 1.1.1.93) (EC 4.1.1.73) (TDH) (D-malate dehydrogenase [decarboxylating]) (EC 1.1.1.83) Length = 358 Score = 51.2 bits (121), Expect = 2e-06 Identities = 41/140 (29%), Positives = 62/140 (44%), Gaps = 1/140 (0%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEG-VELRYKEXXXXXXXXXXXXVPLPDETLAAA 311 I +P DGIGPEV+A VL A + G ++ + V +P + L Sbjct: 6 IAAIPADGIGPEVIAAGLQVLEALEQRSGDFKIHTETFDWGSDYYKKHGVMMPADGLDKL 65 Query: 312 RASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKRE 491 + DAI GA+G + H+ L I G +AN+RP +LP + L+ Sbjct: 66 KKFDAIFFGAVGA---PDVPDHITLWGLRLPICQGFDQYANVRPTKILPGI--TPPLRNC 120 Query: 492 VAEGVDIMVVRELTGGIYFG 551 +D ++VRE + G Y G Sbjct: 121 GPGDLDWVIVRENSEGEYSG 140
>TTUC3_AGRVI (O34296) Probable tartrate dehydrogenase/decarboxylase ttuC' (EC| 1.1.1.93) (EC 4.1.1.73) (TDH) (D-malate dehydrogenase [decarboxylating]) (EC 1.1.1.83) Length = 358 Score = 51.2 bits (121), Expect = 2e-06 Identities = 41/140 (29%), Positives = 62/140 (44%), Gaps = 1/140 (0%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEG-VELRYKEXXXXXXXXXXXXVPLPDETLAAA 311 I +P DGIGPEV+A VL A + G ++ + V +P + L Sbjct: 6 IAAIPADGIGPEVIAAGLQVLEALEQRSGDFKIHTETFDWGSDYYKKHGVMMPADGLDKL 65 Query: 312 RASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKRE 491 + DAI GA+G + H+ L I G +AN+RP +LP + L+ Sbjct: 66 KKFDAIFFGAVGA---PDVPDHITLWGLRLPICQGFDQYANVRPTKILPGI--TPPLRNC 120 Query: 492 VAEGVDIMVVRELTGGIYFG 551 +D ++VRE + G Y G Sbjct: 121 GPGDLDWVIVRENSEGEYSG 140
>LEU3_METTH (O27441) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 329 Score = 50.1 bits (118), Expect = 4e-06 Identities = 40/139 (28%), Positives = 60/139 (43%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I ++PGDGIG EV+ A +L+ ++L + LP+ETL A Sbjct: 6 IAVIPGDGIGVEVMEAALHILNTL----DLDLEFIHADAGDACLKRTGTALPEETLEAVG 61 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 + A L GA G D ++ +R +FANLRP LP + + Sbjct: 62 EARATLFGAAGESAAD----------VIVRLRREFDLFANLRPVKSLPGVPC-------L 104 Query: 495 AEGVDIMVVRELTGGIYFG 551 +D ++VRE T +Y G Sbjct: 105 YPDLDFVIVRENTEDLYVG 123
>LEU3_METJA (Q58130) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 333 Score = 49.3 bits (116), Expect = 7e-06 Identities = 44/139 (31%), Positives = 60/139 (43%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I ++ GDGIG EVV VL A G E Y E LP+ET+ A Sbjct: 4 ICVIEGDGIGKEVVPATIQVLEATGLP--FEFVYAEAGDEVYKRTGKA--LPEETIETAL 59 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 DA+L GA G D ++ +R L +AN+RP V A + + Sbjct: 60 DCDAVLFGAAGETAAD----------VIVKLRHILDTYANIRP-------VKAYKGVKCL 102 Query: 495 AEGVDIMVVRELTGGIYFG 551 +D ++VRE T G+Y G Sbjct: 103 RPDIDYVIVRENTEGLYKG 121
>LEU3_COREF (Q8FPV5) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 340 Score = 48.5 bits (114), Expect = 1e-05 Identities = 49/140 (35%), Positives = 63/140 (45%), Gaps = 1/140 (0%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 + ++ GDGIGPEV A VL A + ++ + L DE LA R Sbjct: 3 LAVIGGDGIGPEVTDEALKVLRALRA----DIETTDLDLGARRYLRNGELLTDEDLALLR 58 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETG-LLNIRAGLGVFANLRPATVLPQLVDASTLKRE 491 DAILLGAIG + E G LL +R L NLRP+ + + S LK Sbjct: 59 EHDAILLGAIGA---PGSVPPGVLERGLLLKLRFALDHHVNLRPSKLYEGV--ESPLKN- 112 Query: 492 VAEGVDIMVVRELTGGIYFG 551 +D +VVRE T G Y G Sbjct: 113 -PGEIDFVVVREGTEGAYTG 131
>IDH_THET8 (P33197) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 496 Score = 48.5 bits (114), Expect = 1e-05 Identities = 41/142 (28%), Positives = 61/142 (42%), Gaps = 3/142 (2%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 IT++PGDGIGPE V VL AA + E+R +P ET+ + R Sbjct: 22 ITVIPGDGIGPECVEATLKVLEAAKAPLAYEVR---EAGASVFRRGIASGVPQETIESIR 78 Query: 315 ASDAILLGAIG---GYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLK 485 + +L G + GY EK + + +R +AN+RP P + Sbjct: 79 KTRVVLKGPLETPVGY----GEK-----SANVTLRKLFETYANVRPVREFPNVPTP---- 125 Query: 486 REVAEGVDIMVVRELTGGIYFG 551 G+D++VVRE +Y G Sbjct: 126 -YAGRGIDLVVVRENVEDLYAG 146
>LEU3_CORJK (Q4JUQ0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 338 Score = 47.8 bits (112), Expect = 2e-05 Identities = 47/139 (33%), Positives = 63/139 (45%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 + ++ GDGIG EV A A VL A ++ VE + L DE L + R Sbjct: 3 LAVIAGDGIGTEVTAEALKVLHAL--RDDVETTDYDLGARRYLRNGEL--LTDEDLDSLR 58 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 DAILLGAIG + + LL +R L NLRP+ + P S+ Sbjct: 59 EHDAILLGAIGDPR--TVPAGVLERGLLLPLRFKLDHAVNLRPSKLYP----GSSSPLAN 112 Query: 495 AEGVDIMVVRELTGGIYFG 551 +D +VVRE T G+Y G Sbjct: 113 PGDIDFVVVREGTEGLYCG 131
>TTUC_BACSU (P42958) Probable tartrate dehydrogenase/decarboxylase (EC| 1.1.1.93) (EC 4.1.1.73) (TDH) (D-malate dehydrogenase [decarboxylating]) (EC 1.1.1.83) Length = 354 Score = 46.6 bits (109), Expect = 5e-05 Identities = 39/138 (28%), Positives = 62/138 (44%), Gaps = 1/138 (0%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVL-SAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAA 311 I +PGDG+G EVVA A+ VL +AA G+ + +P++ + Sbjct: 8 IAAIPGDGVGKEVVAAAEKVLHTAAEVHGGLSFSFTAFPWSCDYYLEHGKMMPEDGIHTL 67 Query: 312 RASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKRE 491 +A+ LGA+G K + H+ LL IR L + N+RPA + + + Sbjct: 68 TQFEAVFLGAVGNPKLVPD--HISLWGLLLKIRRELELSINMRPAKQMAGITSPLLHPND 125 Query: 492 VAEGVDIMVVRELTGGIY 545 D +V+RE + G Y Sbjct: 126 ----FDFVVIRENSEGEY 139
>IDH3A_PONPY (Q5R678) Isocitrate dehydrogenase [NAD] subunit alpha,| mitochondrial precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) Length = 366 Score = 42.0 bits (97), Expect = 0.001 Identities = 39/139 (28%), Positives = 59/139 (42%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 +TL+PGDGIGPE+ A + AA + ++++E +P E A Sbjct: 34 VTLIPGDGIGPEISAAVMKIFDAAKA----PIQWEERNVTAIQGPGGKWMIPSE---AKE 86 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 + D +G G K H P LL +R ++AN+RP + T Sbjct: 87 SMDKNKMGLKGPLKTPIAAGH--PSMNLL-LRKTFDLYANVRPCVSIEGYKTPYT----- 138 Query: 495 AEGVDIMVVRELTGGIYFG 551 V+I+ +RE T G Y G Sbjct: 139 --DVNIVTIRENTEGEYSG 155
>IDH3A_HUMAN (P50213) Isocitrate dehydrogenase [NAD] subunit alpha,| mitochondrial precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) Length = 366 Score = 42.0 bits (97), Expect = 0.001 Identities = 39/139 (28%), Positives = 59/139 (42%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 +TL+PGDGIGPE+ A + AA + ++++E +P E A Sbjct: 34 VTLIPGDGIGPEISAAVMKIFDAAKA----PIQWEERNVTAIQGPGGKWMIPSE---AKE 86 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 + D +G G K H P LL +R ++AN+RP + T Sbjct: 87 SMDKNKMGLKGPLKTPIAAGH--PSMNLL-LRKTFDLYANVRPCVSIEGYKTPYT----- 138 Query: 495 AEGVDIMVVRELTGGIYFG 551 V+I+ +RE T G Y G Sbjct: 139 --DVNIVTIRENTEGEYSG 155
>IDH3A_MACFA (Q28480) Isocitrate dehydrogenase [NAD] subunit alpha,| mitochondrial precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) (Fragment) Length = 347 Score = 42.0 bits (97), Expect = 0.001 Identities = 39/139 (28%), Positives = 59/139 (42%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 +TL+PGDGIGPE+ A + AA + ++++E +P E A Sbjct: 15 VTLIPGDGIGPEISAAVMKIFDAAKA----PIQWEERNVTAIQGPGGKWMIPSE---AKE 67 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 + D +G G K H P LL +R ++AN+RP + T Sbjct: 68 SMDKNKMGLKGPLKTPIAAGH--PSMNLL-LRKTFDLYANVRPCVSIEGYKTPYT----- 119 Query: 495 AEGVDIMVVRELTGGIYFG 551 V+I+ +RE T G Y G Sbjct: 120 --DVNIVTIRENTEGEYSG 136
>IDH3B_MACFA (Q28479) Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial| precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) (Fragment) Length = 381 Score = 41.6 bits (96), Expect = 0.002 Identities = 34/139 (24%), Positives = 62/139 (44%), Gaps = 2/139 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 +T+LPGDG+GPE++ K+V AA V + ++E L ++ L++ + Sbjct: 49 VTMLPGDGVGPELMHAVKEVFKAA----AVPVEFQEHHLSEVQNMASEEKL-EQVLSSMK 103 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGL--LNIRAGLGVFANLRPATVLPQLVDASTLKR 488 + ++G I + K E + +R L +FAN+ LP + Sbjct: 104 ENKVAIIGKI------HTPMEYKGELASYDMRLRRKLDLFANVVHVKSLPGYMTRH---- 153 Query: 489 EVAEGVDIMVVRELTGGIY 545 +D++++RE T G Y Sbjct: 154 ---NNLDLVIIREQTEGEY 169
>IDH3B_RAT (Q68FX0) Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial| precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) Length = 385 Score = 41.6 bits (96), Expect = 0.002 Identities = 34/137 (24%), Positives = 63/137 (45%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 +T+LPGDG+GPE++ K+V AA V + +KE L ++ L++ + Sbjct: 51 VTMLPGDGVGPELMHAVKEVFKAA----AVPVEFKEHHLSEVQNMASEEKL-EQVLSSMK 105 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 + ++G I + E + + + +R L +FAN+ LP + Sbjct: 106 ENKVAIIGKI----YTPMEYKGELASYDMQLRRKLDLFANVVHVKSLPGY-------KTR 154 Query: 495 AEGVDIMVVRELTGGIY 545 +D++++RE T G Y Sbjct: 155 HNNLDLVIIREQTEGEY 171
>IDH3B_HUMAN (O43837) Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial| precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) Length = 385 Score = 41.6 bits (96), Expect = 0.002 Identities = 34/139 (24%), Positives = 62/139 (44%), Gaps = 2/139 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 +T+LPGDG+GPE++ K+V AA V + ++E L ++ L++ + Sbjct: 51 VTMLPGDGVGPELMHAVKEVFKAA----AVPVEFQEHHLSEVQNMASEEKL-EQVLSSMK 105 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGL--LNIRAGLGVFANLRPATVLPQLVDASTLKR 488 + ++G I + K E + +R L +FAN+ LP + Sbjct: 106 ENKVAIIGKI------HTPMEYKGELASYDMRLRRKLDLFANVVHVKSLPGYMTRH---- 155 Query: 489 EVAEGVDIMVVRELTGGIY 545 +D++++RE T G Y Sbjct: 156 ---NNLDLVIIREQTEGEY 171
>IDH3B_CAEEL (Q93353) Probable isocitrate dehydrogenase [NAD] subunit beta,| mitochondrial precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) Length = 379 Score = 41.6 bits (96), Expect = 0.002 Identities = 34/138 (24%), Positives = 64/138 (46%), Gaps = 1/138 (0%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 +T++PGDG+GPE++ +D++ + G+ + ++E + + + R Sbjct: 45 VTIIPGDGVGPELIYTVQDIV----KQTGIPIEFEEIFLSEVHYTRSS-SIENAVESIGR 99 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGL-LNIRAGLGVFANLRPATVLPQLVDASTLKRE 491 ++ L GAI + E L+ GL + +R L +FAN+ L +K Sbjct: 100 NNNVALKGAIEESAVLHTEGELQ---GLNMRLRRSLDLFANVVHIKTL------DGIKTR 150 Query: 492 VAEGVDIMVVRELTGGIY 545 + +D ++VRE T G Y Sbjct: 151 HGKQLDFVIVREQTEGEY 168
>IDH3B_BOVIN (O77784) Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial| precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) (NAD(+)-isocitrate dehydrogenase subunit 1) (IDH1) Length = 385 Score = 40.8 bits (94), Expect = 0.003 Identities = 34/139 (24%), Positives = 62/139 (44%), Gaps = 2/139 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 +T+LPGDG+GPE++ K+V AA V + ++E L ++ L++ + Sbjct: 51 VTMLPGDGVGPELMHAVKEVFKAA----SVPVEFQEHHLSEVQNMASEEKL-EQVLSSMK 105 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGL--LNIRAGLGVFANLRPATVLPQLVDASTLKR 488 + ++G I + K E + +R L +FAN+ LP + Sbjct: 106 ENKVAIIGKI------HTPMEYKGELASYDMRLRRKLDLFANVVHVKSLPGY-------K 152 Query: 489 EVAEGVDIMVVRELTGGIY 545 +D++++RE T G Y Sbjct: 153 TRHNNLDLVIIREQTEGEY 171
>IDH3A_RAT (Q99NA5) Isocitrate dehydrogenase [NAD] subunit alpha,| mitochondrial precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) Length = 366 Score = 40.8 bits (94), Expect = 0.003 Identities = 39/139 (28%), Positives = 59/139 (42%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 +TL+PGDGIGPE+ A + AA + ++++E +P E A Sbjct: 34 VTLIPGDGIGPEISASVMKIFDAAKA----PIQWEERNVTAIQGPGGKWMIPPE---AKE 86 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 + D +G G K H P LL +R ++AN+RP + T Sbjct: 87 SMDKNKMGLKGPLKTPIAAGH--PSMNLL-LRKTFDLYANVRPCVSIEGYKTPYT----- 138 Query: 495 AEGVDIMVVRELTGGIYFG 551 V+I+ +RE T G Y G Sbjct: 139 --DVNIVTIRENTEGEYSG 155
>IDH3A_MOUSE (Q9D6R2) Isocitrate dehydrogenase [NAD] subunit alpha,| mitochondrial precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) Length = 366 Score = 40.8 bits (94), Expect = 0.003 Identities = 39/139 (28%), Positives = 59/139 (42%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 +TL+PGDGIGPE+ A + AA + ++++E +P E A Sbjct: 34 VTLIPGDGIGPEISASVMKIFDAAKA----PIQWEERNVTAIQGPGGKWMIPPE---AKE 86 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 + D +G G K H P LL +R ++AN+RP + T Sbjct: 87 SMDKNKMGLKGPLKTPIAAGH--PSMNLL-LRKTFDLYANVRPCVSIEGYKTPYT----- 138 Query: 495 AEGVDIMVVRELTGGIYFG 551 V+I+ +RE T G Y G Sbjct: 139 --DVNIVTIRENTEGEYSG 155
>IDH3A_BOVIN (P41563) Isocitrate dehydrogenase [NAD] subunit alpha,| mitochondrial precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) (Isocitrate dehydrogenase subunits 3/4) Length = 366 Score = 40.8 bits (94), Expect = 0.003 Identities = 38/139 (27%), Positives = 59/139 (42%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 +TL+PGDGIGPE+ A + AA + ++++E +P E A Sbjct: 34 VTLIPGDGIGPEISAAVMKIFDAAKA----PIQWEERNVAAIQGPGGKWMIPPE---AKE 86 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 + D +G G K H P LL +R ++AN+RP + + Sbjct: 87 SMDKNKMGLKGPLKTPIAAGH--PSMNLL-LRKTFDLYANVRPCVSIEGY-------KTP 136 Query: 495 AEGVDIMVVRELTGGIYFG 551 V+I+ +RE T G Y G Sbjct: 137 YHDVNIVTIRENTEGEYSG 155
>IDH2_YEAST (P28241) Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial| precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) Length = 369 Score = 40.4 bits (93), Expect = 0.003 Identities = 37/144 (25%), Positives = 60/144 (41%), Gaps = 5/144 (3%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 ++ + GDGIGPE+ K + SAA V + + E +PD + + Sbjct: 39 VSFIEGDGIGPEISKSVKKIFSAAN----VPIEW-ESCDVSPIFVNGLTTIPDPAVQSIT 93 Query: 315 ASDAILLGAIG-----GYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDAST 479 + L G + G++ N L +R G+FAN+RPA + Sbjct: 94 KNLVALKGPLATPIGKGHRSLN-----------LTLRKTFGLFANVRPAKSIEGF----- 137 Query: 480 LKREVAEGVDIMVVRELTGGIYFG 551 + E VD++++RE T G Y G Sbjct: 138 --KTTYENVDLVLIRENTEGEYSG 159
>IDH3B_PONPY (Q5RBT4) Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial| precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) Length = 385 Score = 40.0 bits (92), Expect = 0.004 Identities = 33/137 (24%), Positives = 61/137 (44%), Gaps = 2/137 (1%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 +T+LPGDG+GPE++ K+V AA V + ++E L ++ L++ + Sbjct: 51 VTMLPGDGVGPELMHAVKEVFKAA----AVPVEFQEHHLSEVQNMASEEKL-EQVLSSMK 105 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGL--LNIRAGLGVFANLRPATVLPQLVDASTLKR 488 + ++G I + K E + +R L +FAN+ LP + Sbjct: 106 ENKVAIIGKI------HTPMEYKGELASYDMRLRRKLDLFANVVHVKSLPGYMTRH---- 155 Query: 489 EVAEGVDIMVVRELTGG 539 +D++++RE T G Sbjct: 156 ---NNLDLVIIREQTEG 169
>IDH3A_DROME (Q9VWH4) Probable isocitrate dehydrogenase [NAD] subunit alpha,| mitochondrial precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) Length = 377 Score = 39.7 bits (91), Expect = 0.006 Identities = 35/139 (25%), Positives = 59/139 (42%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 +TL+PGDGIGPE+ A + + +AA V + ++ +P AA Sbjct: 50 VTLIPGDGIGPEISAAVQKIFTAA----NVPIEWEAVDVTPVRGPDGKFGIPQ---AAID 102 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 + + +G G + H L +R ++AN+RP L + + Sbjct: 103 SVNTNKIGLKGPLMTPVGKGHRSLN---LALRKEFNLYANVRPCRSLEGY-------KTL 152 Query: 495 AEGVDIMVVRELTGGIYFG 551 + VD++ +RE T G Y G Sbjct: 153 YDDVDVVTIRENTEGEYSG 171
>DLPA_LEGPH (Q48806) Protein dlpA| Length = 615 Score = 39.3 bits (90), Expect = 0.008 Identities = 39/148 (26%), Positives = 60/148 (40%), Gaps = 9/148 (6%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 I +LPGDGIG EV V V L Y + + P T Sbjct: 9 IAVLPGDGIGIEVTEATLPVFEVLDVP--VILNYGDIGWEFWKKEGAAI--PSRTWQLIA 64 Query: 315 ASDAILLGAI-------GGYKWDNNEKHLKP--ETGLLNIRAGLGVFANLRPATVLPQLV 467 +SD +LLGAI + N K P + ++ +R GL +FAN+RP + Sbjct: 65 SSDTVLLGAITSKPQREAKQELSNALKKSNPYYVSPVIQLRQGLDLFANVRPCFSID--- 121 Query: 468 DASTLKREVAEGVDIMVVRELTGGIYFG 551 + ++ + ++RE + G+Y G Sbjct: 122 -------DQSKPFNFCIIRENSEGLYCG 142
>IDH2_KLULA (O94230) Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial| precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) Length = 368 Score = 39.3 bits (90), Expect = 0.008 Identities = 37/144 (25%), Positives = 61/144 (42%), Gaps = 5/144 (3%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 ++ + GDG+GPE+ K + SAA K +E E +PD +A+ Sbjct: 38 VSFIEGDGVGPEISKSVKAIFSAA--KVPIEW---ESCDVSPIFVNGLTTIPDPAVASIN 92 Query: 315 ASDAILLGAIG-----GYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDAST 479 + L G + G++ N L +R G+FAN+RPA + Sbjct: 93 KNLIALKGPLATPIGKGHRSLN-----------LTLRKTFGLFANVRPAKSIEGY----- 136 Query: 480 LKREVAEGVDIMVVRELTGGIYFG 551 + E V+++++RE T G Y G Sbjct: 137 --KTTYENVNLVLIRENTEGEYSG 158
>IDH_CALNO (P96318) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 429 Score = 39.3 bits (90), Expect = 0.008 Identities = 41/147 (27%), Positives = 59/147 (40%), Gaps = 8/147 (5%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELR---YKEXXXXXXXXXXXXVPLPDETLA 305 + GDGIGPE+V AK VL AA K R + E LPD TL Sbjct: 35 VAYFKGDGIGPEIVESAKKVLDAAVDKAYGGTRRIVWWEVTAGEEAQKECGSLLPDGTLQ 94 Query: 306 AARASDAILLGAI-----GGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVD 470 A + + L G + GG++ N + +R L +++N+RP Q Sbjct: 95 AFKLARVNLKGPLTTPVGGGFRSLN-----------VTLRMVLDLYSNVRPVKWYGQPTP 143 Query: 471 ASTLKREVAEGVDIMVVRELTGGIYFG 551 E +D ++ RE T +Y G Sbjct: 144 HCH-----PENIDWVIFRENTEDVYAG 165
>IDH2_SCHPO (Q9USP8) Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial| precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) Length = 378 Score = 38.9 bits (89), Expect = 0.010 Identities = 35/139 (25%), Positives = 59/139 (42%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 +T++ GDGIGPE+ + + AA K +E E +PD+ + R Sbjct: 48 VTMIAGDGIGPEIAQSVERIFKAA--KVPIEW---ERVKVYPILKNGTTTIPDDAKESVR 102 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 + L G + + H+ L +R G+FAN+RP + T + Sbjct: 103 KNKVALKGPLA---TPIGKGHVSMN---LTLRRTFGLFANVRPCVSI-------TGYKTP 149 Query: 495 AEGVDIMVVRELTGGIYFG 551 + V+ +++RE T G Y G Sbjct: 150 YDNVNTVLIRENTEGEYSG 168
>LEU3_SOLTU (P29696) 3-isopropylmalate dehydrogenase, chloroplast precursor (EC| 1.1.1.85) (Beta-IPM dehydrogenase) (IMDH) (3-IPM-DH) Length = 357 Score = 38.9 bits (89), Expect = 0.010 Identities = 37/143 (25%), Positives = 59/143 (41%), Gaps = 5/143 (3%) Frame = +3 Query: 138 TLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAARA 317 TL PGDGIGPE+ + + A V + ++E L E+L + R Sbjct: 40 TLFPGDGIGPEIAESVRQIFKVA----EVPIEWEEHYVGTEVDPRTNSFLTWESLESVRR 95 Query: 318 SDAILLGAIG-----GYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTL 482 + L G + G++ N L +R L ++AN+RP LP Sbjct: 96 NKVGLKGPMATPIGKGHRSLN-----------LTLRKELNLYANVRPCYSLPGY------ 138 Query: 483 KREVAEGVDIMVVRELTGGIYFG 551 + + V+++ +RE T G Y G Sbjct: 139 -KTRYDDVNLITIRENTEGEYSG 160
>IDH3A_CAEEL (Q93714) Probable isocitrate dehydrogenase [NAD] subunit alpha,| mitochondrial precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) Length = 358 Score = 38.1 bits (87), Expect = 0.017 Identities = 33/139 (23%), Positives = 57/139 (41%) Frame = +3 Query: 135 ITLLPGDGIGPEVVAVAKDVLSAAGSKEGVELRYKEXXXXXXXXXXXXVPLPDETLAAAR 314 +TL+PGDGIGPE+ A + + AA + + + +P + Sbjct: 27 VTLIPGDGIGPEISASVQKIFEAADA----PIAWDPVDVTPVKGRDGVFRIPSRCIELMH 82 Query: 315 ASDAILLGAIGGYKWDNNEKHLKPETGLLNIRAGLGVFANLRPATVLPQLVDASTLKREV 494 A+ +G G + + H L +R ++AN+RP L + + Sbjct: 83 ANK---VGLKGPLETPIGKGHRSLN---LAVRKEFSLYANVRPCRSLEG-------HKTL 129 Query: 495 AEGVDIMVVRELTGGIYFG 551 + VD++ +RE T G Y G Sbjct: 130 YDNVDVVTIRENTEGEYSG 148 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 49,876,664 Number of Sequences: 219361 Number of extensions: 855368 Number of successful extensions: 4021 Number of sequences better than 10.0: 275 Number of HSP's better than 10.0 without gapping: 3443 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 3692 length of database: 80,573,946 effective HSP length: 106 effective length of database: 57,321,680 effective search space used: 4585734400 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
