>TPK1_HUMAN (Q9H3S4) Thiamin pyrophosphokinase 1 (EC 2.7.6.2) (Thiamine|
           pyrophosphokinase 1) (hTPK1) (Placental protein 20)
           (PP20)
          Length = 243

 Score = 89.4 bits (220), Expect = 5e-18
 Identities = 46/104 (44%), Positives = 65/104 (62%)
 Frame = +1

Query: 160 VSYAVVVLNQRLPRFAPLLWTRADLRVCADGGANRVFDGMPELLPGEDPDEVRTRYKPDA 339
           + Y +V+LNQ L  +   LW +A LR CADGGANR++D    +  GE     R  + P+ 
Sbjct: 17  LKYCLVILNQPLDNYFRHLWNKALLRACADGGANRLYD----ITEGE-----RESFLPEF 67

Query: 340 IEGDMDSVRPEVKEYYSSLGTQIIDDSHDQDTTDLNKCISFITK 471
           I GD DS+RPEV+EYY++ G ++I  + DQD TD  KC+  + K
Sbjct: 68  INGDFDSIRPEVREYYATKGCELI-STPDQDHTDFTKCLKMLQK 110

>TPK1_MOUSE (Q9R0M5) Thiamin pyrophosphokinase 1 (EC 2.7.6.2) (Thiamine|
           pyrophosphokinase 1) (mTPK1)
          Length = 243

 Score = 83.6 bits (205), Expect = 3e-16
 Identities = 46/104 (44%), Positives = 61/104 (58%)
 Frame = +1

Query: 160 VSYAVVVLNQRLPRFAPLLWTRADLRVCADGGANRVFDGMPELLPGEDPDEVRTRYKPDA 339
           + Y +VVLNQ L      LW +A LR CADGGAN ++D    L  GE     R  + P+ 
Sbjct: 17  LKYCLVVLNQPLDARFRHLWKKALLRACADGGANHLYD----LTEGE-----RESFLPEF 67

Query: 340 IEGDMDSVRPEVKEYYSSLGTQIIDDSHDQDTTDLNKCISFITK 471
           + GD DS+RPEVKEYY+  G  +I  + DQD TD  KC+  + +
Sbjct: 68  VSGDFDSIRPEVKEYYTKKGCDLI-STPDQDHTDFTKCLQVLQR 110

>THI80_YEAST (P35202) Thiamine pyrophosphokinase (EC 2.7.6.2) (TPK) (Thiamine|
           kinase)
          Length = 319

 Score = 67.4 bits (163), Expect = 2e-11
 Identities = 38/109 (34%), Positives = 64/109 (58%), Gaps = 3/109 (2%)
 Frame = +1

Query: 172 VVVLNQRLPRFAPL---LWTRADLRVCADGGANRVFDGMPELLPGEDPDEVRTRYKPDAI 342
           +++LNQ++    PL   +W   DL+VCADG ANR++D +      +D + +R +Y P+ I
Sbjct: 41  LLILNQKIDIPRPLFYKIWKLHDLKVCADGAANRLYDYL------DDDETLRIKYLPNYI 94

Query: 343 EGDMDSVRPEVKEYYSSLGTQIIDDSHDQDTTDLNKCISFITKNPPGPD 489
            GD+DS+  +V +YY      II  +  Q +TD  KC++ I+ +   P+
Sbjct: 95  IGDLDSLSEKVYKYYRKNKVTIIKQT-TQYSTDFTKCVNLISLHFNSPE 142

>TNR3_SCHPO (P41888) Thiamine pyrophosphokinase (EC 2.7.6.2) (TPK) (Thiamine|
           kinase)
          Length = 569

 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 42/107 (39%), Positives = 57/107 (53%), Gaps = 4/107 (3%)
 Frame = +1

Query: 166 YAVVVLNQRLP----RFAPLLWTRADLRVCADGGANRVFDGMPELLPGEDPDEVRTRYKP 333
           +AV++LNQ +     RF  L W RA +RVCADGGAN++ +    L             KP
Sbjct: 353 FAVLLLNQPIDIPDDRFRTL-WKRASIRVCADGGANQLRNYDSSL-------------KP 398

Query: 334 DAIEGDMDSVRPEVKEYYSSLGTQIIDDSHDQDTTDLNKCISFITKN 474
           D + GD DS+  E K YY  +G  I+ D   Q+TTD  KC   I ++
Sbjct: 399 DYVVGDFDSLTDETKAYYKEMGVNIVFDP-CQNTTDFMKCHKIIKEH 444

>SCN1_LOLBL (Q05973) Sodium channel protein I, brain|
          Length = 1522

 Score = 31.6 bits (70), Expect = 1.2
 Identities = 32/112 (28%), Positives = 45/112 (40%), Gaps = 7/112 (6%)
 Frame = -3

Query: 483 PRWIFGDERYAFVQV----CGVLIM*IIDYLGTQTGIVFLHFWPYRIHISFDCIGLVPRA 316
           PRW F D  ++F+ V    CG  I  + D +    G+ FL F P  +       G     
Sbjct: 569 PRWNFNDFLHSFMMVFRILCGEWIEPMYDCMRACNGLCFLIFIPVTV------FGKTLFF 622

Query: 315 DLVGVLAGEQLRHAVEDPVGAAVRAHPQVSSGP*QGREAREALVED---DDG 169
             +G++ G      VE  V  +  A P   S P   RE   +  +D   DDG
Sbjct: 623 LFIGLVLGAFGSDTVEQEVEVSSFALPGPESKPCSVRERGISATDDNVKDDG 674

>MPIP_YEAST (P23748) M-phase inducer phosphatase (EC 3.1.3.48) (Mitosis|
           initiation protein MIH1) (Mitotic inducer homolog)
          Length = 554

 Score = 30.8 bits (68), Expect = 2.1
 Identities = 25/89 (28%), Positives = 34/89 (38%), Gaps = 11/89 (12%)
 Frame = +1

Query: 247 DGGANRVFDGMPELLPGEDPDEVRTRYKPDAIEGDMDSVRPEVKEYYS-----------S 393
           DGG   VFD  PEL        + ++      E +MD  R E K + +           S
Sbjct: 358 DGGYKAVFDNFPELCYPRQYVGMNSQENLLNCEQEMDKFRRESKRFATKNNSFRKLASPS 417

Query: 394 LGTQIIDDSHDQDTTDLNKCISFITKNPP 480
                  DSH   TT  +  +SF  + PP
Sbjct: 418 NPNFFYRDSHQSSTTMASSALSFRFEPPP 446

>GLUQ_BIFLO (Q8G4X3) Glutamyl-Q tRNA(Asp) synthetase (EC 6.1.1.-) (Glu-Q-RSs)|
          Length = 379

 Score = 30.0 bits (66), Expect = 3.6
 Identities = 20/61 (32%), Positives = 29/61 (47%), Gaps = 3/61 (4%)
 Frame = +1

Query: 208 PLLWTRADLRVCA---DGGANRVFDGMPELLPGEDPDEVRTRYKPDAIEGDMDSVRPEVK 378
           P   +RAD+R  +   +G    V+ G    L  + PDEVR R     + GD  S+R  + 
Sbjct: 105 PCFCSRADIRAASAPNEGDGFMVYPGTCRRLLHDHPDEVRAR----LVRGDQHSIRIAMP 160

Query: 379 E 381
           E
Sbjct: 161 E 161

>MYT1L_RAT (P70475) Myelin transcription factor 1-like protein (MyT1L protein)|
           (Neural zinc finger factor 1) (NZF-1)
          Length = 1187

 Score = 30.0 bits (66), Expect = 3.6
 Identities = 16/51 (31%), Positives = 26/51 (50%)
 Frame = +1

Query: 298 EDPDEVRTRYKPDAIEGDMDSVRPEVKEYYSSLGTQIIDDSHDQDTTDLNK 450
           + P E   + KP A++ D  SV     E Y S GT+ +DD  + D  + ++
Sbjct: 66  KQPQEPAPKRKPFAVKADSSSV----DECYESDGTEDMDDKEEDDDEEFSE 112

>MYT1L_MOUSE (P97500) Myelin transcription factor 1-like protein (MyT1L protein)|
           (Postmitotic neural gene 1 protein) (Zinc finger protein
           Png-1) (Neural zinc finger factor 1) (NZF-1)
          Length = 1187

 Score = 30.0 bits (66), Expect = 3.6
 Identities = 16/51 (31%), Positives = 26/51 (50%)
 Frame = +1

Query: 298 EDPDEVRTRYKPDAIEGDMDSVRPEVKEYYSSLGTQIIDDSHDQDTTDLNK 450
           + P E   + KP A++ D  SV     E Y S GT+ +DD  + D  + ++
Sbjct: 66  KQPQEPAPKRKPFAVKADSSSV----DECYESDGTEDMDDKEEDDDEEFSE 112

>CATZ_RAT (Q9R1T3) Cathepsin Z precursor (EC 3.4.22.-) (Cathepsin Y)|
          Length = 306

 Score = 29.6 bits (65), Expect = 4.7
 Identities = 12/32 (37%), Positives = 16/32 (50%)
 Frame = +1

Query: 154 NGVSYAVVVLNQRLPRFAPLLWTRADLRVCAD 249
           NGV+YA V  NQ +P++    W        AD
Sbjct: 74  NGVNYASVTRNQHIPQYCGSCWAHGSTSALAD 105

>CATZ_MOUSE (Q9WUU7) Cathepsin Z precursor (EC 3.4.22.-)|
          Length = 306

 Score = 29.6 bits (65), Expect = 4.7
 Identities = 12/32 (37%), Positives = 16/32 (50%)
 Frame = +1

Query: 154 NGVSYAVVVLNQRLPRFAPLLWTRADLRVCAD 249
           NGV+YA V  NQ +P++    W        AD
Sbjct: 74  NGVNYASVTRNQHIPQYCGSCWAHGSTSAMAD 105

>DOCK9_HUMAN (Q9BZ29) Dedicator of cytokinesis protein 9 (Cdc42 guanine|
           nucleotide exchange factor zizimin 1)
          Length = 2069

 Score = 29.3 bits (64), Expect = 6.2
 Identities = 22/92 (23%), Positives = 42/92 (45%), Gaps = 9/92 (9%)
 Frame = +1

Query: 247 DGGANRVFDGMPELLPGEDPDEVRTRYK---------PDAIEGDMDSVRPEVKEYYSSLG 399
           +G  + +   +PEL       E++ + +         PDA + D  S  PEVK +    G
Sbjct: 306 EGSGSGLDSYLPELAKSAREAEIKLKSESRVKLFYLDPDAQKLDFSSAEPEVKSFEEKFG 365

Query: 400 TQIIDDSHDQDTTDLNKCISFITKNPPGPDSS 495
            +I+   +D  + +L  C++   +N  GP ++
Sbjct: 366 KRILVKCNDL-SFNLQCCVA---ENEEGPTTN 393

>ATG26_CANAL (Q5A950) Sterol 3-beta-glucosyltransferase (EC 2.4.1.173)|
           (Autophagy-related protein 26) (UDP-glycosyltransferase
           51)
          Length = 1513

 Score = 29.3 bits (64), Expect = 6.2
 Identities = 13/40 (32%), Positives = 19/40 (47%)
 Frame = +1

Query: 349 DMDSVRPEVKEYYSSLGTQIIDDSHDQDTTDLNKCISFIT 468
           D D+  PE +  Y SL  ++  D  D+D   L   + F T
Sbjct: 35  DADNENPEHRTTYHSLSGRVNHDDDDEDVAKLEDIVGFFT 74

>SWR1_ASPFU (Q4WAS9) Helicase swr1 (EC 3.6.1.-)|
          Length = 1695

 Score = 28.9 bits (63), Expect = 8.1
 Identities = 17/41 (41%), Positives = 22/41 (53%), Gaps = 3/41 (7%)
 Frame = +2

Query: 218 GPELTCGCARTAAPTGSSTACRSCS---PARTPTRSARGTS 331
           G  LT G  RTA P G+S   R  S   P +TP+R+   +S
Sbjct: 162 GGNLTTGSPRTATPRGASARRRRISRSPPRQTPSRTRSQSS 202

>PDE2_YEAST (P06776) 3',5'-cyclic-nucleotide phosphodiesterase 2 (EC 3.1.4.17)|
           (PDEase 2) (High-affinity cAMP phosphodiesterase)
          Length = 526

 Score = 28.9 bits (63), Expect = 8.1
 Identities = 13/32 (40%), Positives = 17/32 (53%)
 Frame = -2

Query: 430 PDHVNHRLFGYPNWNSIPSLLALQNPYLLRLH 335
           PD +N   +G  N NS+P+     N Y L LH
Sbjct: 132 PDGINKNSYGTVNGNSVPTQACEANIYTLLLH 163

>TPK1_CAEEL (P30636) Thiamin pyrophosphokinase 1 (EC 2.7.6.2) (Thiamine|
           pyrophosphokinase 1) (TPK1)
          Length = 243

 Score = 28.9 bits (63), Expect = 8.1
 Identities = 24/83 (28%), Positives = 35/83 (42%)
 Frame = +1

Query: 214 LWTRADLRVCADGGANRVFDGMPELLPGEDPDEVRTRYKPDAIEGDMDSVRPEVKEYYSS 393
           LW +A  RV  DG  N       E+L  +   E      P  I GD DS+  ++    + 
Sbjct: 36  LWNKAKYRVATDGAVN-------EILKRKSFVE-----WPHIICGDFDSINKQIDTKNAK 83

Query: 394 LGTQIIDDSHDQDTTDLNKCISF 462
                +    DQD TDL+K + +
Sbjct: 84  -----VVHLPDQDYTDLSKSVQW 101


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.316    0.135    0.405 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 52,967,809
Number of Sequences: 219361
Number of extensions: 1051943
Number of successful extensions: 3643
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 3508
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3631
length of database: 80,573,946
effective HSP length: 104
effective length of database: 57,760,402
effective search space used: 3581144924
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)