>DCN1L_DROME (Q9VUQ8) DCN1-like protein (Defective in cullin neddylation protein|
           1-like protein)
          Length = 288

 Score = 65.9 bits (159), Expect = 8e-11
 Identities = 35/89 (39%), Positives = 50/89 (56%), Gaps = 5/89 (5%)
 Frame = +3

Query: 309 MEGMRDGIFGDIHKLMSVL-----EFDDVSQFNSFYDFVFFISRENGQKNITVQKALAAW 473
           + GM D     I KL + L     E +D  +F  FY F F  +++ GQK I ++ A+A W
Sbjct: 119 INGMCDLGIDSIDKLKTKLPILEQELNDAGKFKDFYHFTFNYAKDPGQKGIDLEMAIAYW 178

Query: 474 RIVLLGRFRLLDRWCNFVQKYQRPHISED 560
            IVL GRF+ LD WC F+++  +  IS D
Sbjct: 179 CIVLSGRFKFLDIWCQFLEEKHKRAISRD 207

>DCNL2_HUMAN (Q6PH85) DCN1-like protein 2 (Defective in cullin neddylation|
           protein 2-like protein 2) (DCUN1 domain-containing
           protein 2)
          Length = 259

 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 29/89 (32%), Positives = 50/89 (56%), Gaps = 5/89 (5%)
 Frame = +3

Query: 309 MEGMRDGIFGDIHKLMSVL-----EFDDVSQFNSFYDFVFFISRENGQKNITVQKALAAW 473
           ++GM +     + KL ++L     E  D ++F  FY F F  ++  GQK + ++ A+A W
Sbjct: 123 LDGMTELGCDSMEKLKALLPRLEQELKDTAKFKDFYQFTFTFAKNPGQKGLDLEMAVAYW 182

Query: 474 RIVLLGRFRLLDRWCNFVQKYQRPHISED 560
           ++VL GRF+ LD W  F+ ++ +  I  D
Sbjct: 183 KLVLSGRFKFLDLWNTFLMEHHKRSIPRD 211

>DCNL1_CHICK (Q5ZKU1) DCN1-like protein 1 (Defective in cullin neddylation|
           protein 1-like protein 1) (DCUN1 domain-containing
           protein 1)
          Length = 259

 Score = 57.4 bits (137), Expect = 3e-08
 Identities = 29/92 (31%), Positives = 50/92 (54%), Gaps = 5/92 (5%)
 Frame = +3

Query: 300 IDNMEGMRDGIFGDIHKLMSVL-----EFDDVSQFNSFYDFVFFISRENGQKNITVQKAL 464
           ++ M+GM +     I KL + +     E  +  +F  FY F F  ++  GQK + ++ A+
Sbjct: 120 LEFMDGMTELGCDSIEKLKAQIPKMEQELKEPGRFKDFYQFTFNFAKNPGQKGLDLEMAI 179

Query: 465 AAWRIVLLGRFRLLDRWCNFVQKYQRPHISED 560
           A W +VL GRF+ LD W  F+ ++ +  I +D
Sbjct: 180 AYWNLVLNGRFKFLDLWNKFLLEHHKRSIPKD 211

>DCNL1_MOUSE (Q9QZ73) DCN1-like protein 1 (Defective in cullin neddylation|
           protein 1-like protein 1) (DCUN1 domain-containing
           protein 1) (Testis-specific protein 3)
          Length = 259

 Score = 57.0 bits (136), Expect = 4e-08
 Identities = 29/89 (32%), Positives = 48/89 (53%), Gaps = 5/89 (5%)
 Frame = +3

Query: 309 MEGMRDGIFGDIHKLMSVL-----EFDDVSQFNSFYDFVFFISRENGQKNITVQKALAAW 473
           M+GM +     I KL + +     E  +  +F  FY F F  ++  GQK + ++ A+A W
Sbjct: 123 MDGMTELGCDSIEKLKAQIPKMEQELKEPGRFKDFYQFTFNFAKNPGQKGLDLEMAIAYW 182

Query: 474 RIVLLGRFRLLDRWCNFVQKYQRPHISED 560
            +VL GRF+ LD W  F+ ++ +  I +D
Sbjct: 183 NLVLNGRFKFLDLWNKFLLEHHKRSIPKD 211

>DCNL1_HUMAN (Q96GG9) DCN1-like protein 1 (Defective in cullin neddylation|
           protein 1-like protein 1) (DCUN1 domain-containing
           protein 1) (Squamous cell carcinoma-related oncogene)
          Length = 259

 Score = 57.0 bits (136), Expect = 4e-08
 Identities = 29/89 (32%), Positives = 48/89 (53%), Gaps = 5/89 (5%)
 Frame = +3

Query: 309 MEGMRDGIFGDIHKLMSVL-----EFDDVSQFNSFYDFVFFISRENGQKNITVQKALAAW 473
           M+GM +     I KL + +     E  +  +F  FY F F  ++  GQK + ++ A+A W
Sbjct: 123 MDGMTELGCDSIEKLKAQIPKMEQELKEPGRFKDFYQFTFNFAKNPGQKGLDLEMAIAYW 182

Query: 474 RIVLLGRFRLLDRWCNFVQKYQRPHISED 560
            +VL GRF+ LD W  F+ ++ +  I +D
Sbjct: 183 NLVLNGRFKFLDLWNKFLLEHHKRSIPKD 211

>DCNL2_MOUSE (Q8BZJ7) DCN1-like protein 2 (Defective in cullin neddylation|
           protein 2-like protein 2) (DCUN1 domain-containing
           protein 2)
          Length = 258

 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 22/59 (37%), Positives = 37/59 (62%)
 Frame = +3

Query: 366 EFDDVSQFNSFYDFVFFISRENGQKNITVQKALAAWRIVLLGRFRLLDRWCNFVQKYQR 542
           E  D ++F   Y F F  ++  GQK + ++ A+A W++VL GRF+ LD W  F++ ++R
Sbjct: 147 ELKDPAKFKDLYQFTFTFAKNPGQKGLDLEMAVAYWKLVLSGRFKFLDLWNTFLEHHKR 205

>DCN1_YARLI (Q6C0B6) Defective in cullin neddylation protein 1|
          Length = 240

 Score = 45.8 bits (107), Expect = 8e-05
 Identities = 19/61 (31%), Positives = 35/61 (57%)
 Frame = +3

Query: 381 SQFNSFYDFVFFISRENGQKNITVQKALAAWRIVLLGRFRLLDRWCNFVQKYQRPHISED 560
           + F   Y F +    + GQ+ +  + A+  WR++L G++  LD+W +FV +  + +IS D
Sbjct: 141 ADFQKIYKFTYGFLLQEGQRVLPQETAVDYWRLLLTGKYEHLDKWLSFVTEKYKRNISRD 200

Query: 561 A 563
           A
Sbjct: 201 A 201

>DCN1_USTMA (Q4PF67) Defective in cullin neddylation protein 1|
          Length = 319

 Score = 32.3 bits (72), Expect = 0.95
 Identities = 11/33 (33%), Positives = 21/33 (63%)
 Frame = +3

Query: 387 FNSFYDFVFFISRENGQKNITVQKALAAWRIVL 485
           +   Y++ +  +R  GQK++ ++ ALA W +VL
Sbjct: 199 YEKVYEYTYAFARREGQKSLALENALAFWDLVL 231

>DCN1_CAEEL (Q9U3C8) Defective in cullin neddylation protein 1|
          Length = 295

 Score = 32.0 bits (71), Expect = 1.2
 Identities = 15/62 (24%), Positives = 33/62 (53%)
 Frame = +3

Query: 342 IHKLMSVLEFDDVSQFNSFYDFVFFISRENGQKNITVQKALAAWRIVLLGRFRLLDRWCN 521
           I  + S LE  D ++F+  Y F F  ++    +N+ ++ A+  W ++   R  ++ +W +
Sbjct: 144 IDSINSGLE-SDKAKFHELYLFAFNYAKSAACRNLDLETAICCWDVLFGQRSTIMTQWID 202

Query: 522 FV 527
           F+
Sbjct: 203 FL 204

>ALDH1_MACPR (Q29490) Aldehyde dehydrogenase, cytosolic 1 (EC 1.2.1.3) (ALDH|
           class 1) (ETA-crystallin)
          Length = 501

 Score = 31.2 bits (69), Expect = 2.1
 Identities = 18/62 (29%), Positives = 32/62 (51%), Gaps = 2/62 (3%)
 Frame = +3

Query: 291 SRTIDNMEGMRDGIFGDIHKLMSVLEFDDVSQ--FNSFYDFVFFISRENGQKNITVQKAL 464
           S   D+M   ++ IFG + ++M     D+V +   N++Y  V  +  ++  K +TV  AL
Sbjct: 388 SNVTDDMRIAKEEIFGPVQQIMKFKSLDEVIKRANNTYYGLVAGVFTKDLDKAVTVSSAL 447

Query: 465 AA 470
            A
Sbjct: 448 QA 449

>ALDH1_ELEED (Q28399) Aldehyde dehydrogenase, cytosolic 1 (EC 1.2.1.3) (ALDH|
           class 1) (ETA-crystallin)
          Length = 501

 Score = 31.2 bits (69), Expect = 2.1
 Identities = 18/62 (29%), Positives = 32/62 (51%), Gaps = 2/62 (3%)
 Frame = +3

Query: 291 SRTIDNMEGMRDGIFGDIHKLMSVLEFDDVSQ--FNSFYDFVFFISRENGQKNITVQKAL 464
           S   D+M   ++ IFG + ++M     D+V +   N++Y  V  +  ++  K +TV  AL
Sbjct: 388 SNVTDDMRIAKEEIFGPVQQIMKFKSLDEVIKRANNTYYGLVAGVFTKDLDKAVTVSSAL 447

Query: 465 AA 470
            A
Sbjct: 448 QA 449

>AL1A1_MOUSE (P24549) Retinal dehydrogenase 1 (EC 1.2.1.36) (RalDH1) (RALDH 1)|
           (Aldehyde dehydrogenase family 1 member A1) (Aldehyde
           dehydrogenase, cytosolic) (ALHDII) (ALDH-E1)
          Length = 500

 Score = 31.2 bits (69), Expect = 2.1
 Identities = 23/80 (28%), Positives = 37/80 (46%), Gaps = 2/80 (2%)
 Frame = +3

Query: 291 SRTIDNMEGMRDGIFGDIHKLMSVLEFDDVSQ--FNSFYDFVFFISRENGQKNITVQKAL 464
           S   D M   ++ IFG + ++M     DDV +   N+ Y     +  ++  K ITV  AL
Sbjct: 387 SNVTDEMRIAKEEIFGPVQQIMKFKSVDDVIKRANNTTYGLAAGLFTKDLDKAITVSSAL 446

Query: 465 AAWRIVLLGRFRLLDRWCNF 524
            A  +V +  + +L   C F
Sbjct: 447 QA-GVVWVNCYMMLSAQCPF 465

>AL1A1_HUMAN (P00352) Retinal dehydrogenase 1 (EC 1.2.1.36) (RalDH1) (RALDH 1)|
           (Aldehyde dehydrogenase family 1 member A1) (Aldehyde
           dehydrogenase, cytosolic) (ALHDII) (ALDH-E1)
          Length = 500

 Score = 31.2 bits (69), Expect = 2.1
 Identities = 19/62 (30%), Positives = 30/62 (48%), Gaps = 2/62 (3%)
 Frame = +3

Query: 291 SRTIDNMEGMRDGIFGDIHKLMSVLEFDDVSQ--FNSFYDFVFFISRENGQKNITVQKAL 464
           S   D M   ++ IFG + ++M     DDV +   N+FY     +  ++  K IT+  AL
Sbjct: 387 SNVTDEMRIAKEEIFGPVQQIMKFKSLDDVIKRANNTFYGLSAGVFTKDIDKAITISSAL 446

Query: 465 AA 470
            A
Sbjct: 447 QA 448

>DCN1_SCHPO (Q8WZK4) Defective in cullin neddylation protein 1|
          Length = 251

 Score = 30.8 bits (68), Expect = 2.8
 Identities = 14/52 (26%), Positives = 29/52 (55%)
 Frame = +3

Query: 375 DVSQFNSFYDFVFFISRENGQKNITVQKALAAWRIVLLGRFRLLDRWCNFVQ 530
           D S   + Y + + ++ + G+K ++   A+  ++I+L   F LLD W  F++
Sbjct: 140 DASLQKAIYIYTYPLACDKGKKTLSTSIAIEFFQILLKDTFPLLDDWIAFLK 191

>AL1A1_RAT (P51647) Retinal dehydrogenase 1 (EC 1.2.1.36) (RalDH1) (RALDH 1)|
           (Aldehyde dehydrogenase family 1 member A1) (Aldehyde
           dehydrogenase, cytosolic) (ALHDII) (ALDH-E1)
          Length = 500

 Score = 30.8 bits (68), Expect = 2.8
 Identities = 22/80 (27%), Positives = 37/80 (46%), Gaps = 2/80 (2%)
 Frame = +3

Query: 291 SRTIDNMEGMRDGIFGDIHKLMSVLEFDDVSQ--FNSFYDFVFFISRENGQKNITVQKAL 464
           S   D M   ++ IFG + ++M     DDV +   N+ Y     +  ++  + ITV  AL
Sbjct: 387 SNVTDEMRIAKEEIFGPVQQIMKFKSIDDVIKRANNTTYGLAAGVFTKDLDRAITVSSAL 446

Query: 465 AAWRIVLLGRFRLLDRWCNF 524
            A  +V +  + +L   C F
Sbjct: 447 QA-GVVWVNCYMILSAQCPF 465

>AL1A1_MACFA (Q8HYE4) Retinal dehydrogenase 1 (EC 1.2.1.36) (RalDH1) (RALDH 1)|
           (Aldehyde dehydrogenase family 1 member A1) (Aldehyde
           dehydrogenase, cytosolic) (ALHDII) (ALDH-E1)
          Length = 500

 Score = 30.4 bits (67), Expect = 3.6
 Identities = 18/62 (29%), Positives = 29/62 (46%), Gaps = 2/62 (3%)
 Frame = +3

Query: 291 SRTIDNMEGMRDGIFGDIHKLMSVLEFDDVSQ--FNSFYDFVFFISRENGQKNITVQKAL 464
           S   D M   ++ IFG + ++M     DDV +   N+FY     +   +  K +T+  AL
Sbjct: 387 SNVTDEMRIAKEEIFGPVQQIMKFKSLDDVIKRANNTFYGLSAGVFTNDIDKAVTISSAL 446

Query: 465 AA 470
            A
Sbjct: 447 QA 448

>ALDH2_MACPR (Q29491) Aldehyde dehydrogenase, cytosolic 2 (EC 1.2.1.3) (ALDH|
           class 1) (Non-lens ALDH1) (ALDH1-NL) (Fragment)
          Length = 240

 Score = 30.0 bits (66), Expect = 4.7
 Identities = 18/62 (29%), Positives = 30/62 (48%), Gaps = 2/62 (3%)
 Frame = +3

Query: 291 SRTIDNMEGMRDGIFGDIHKLMSVLEFDDVSQ--FNSFYDFVFFISRENGQKNITVQKAL 464
           S   D M   ++ IFG + ++M     D+V +   N+FY     +  ++  K +TV  AL
Sbjct: 127 SNVTDEMRIAKEEIFGPVQQIMKFKSLDEVIKRANNTFYGLAAGVFTKDLDKAVTVSAAL 186

Query: 465 AA 470
            A
Sbjct: 187 QA 188

>AL1A1_SHEEP (P51977) Retinal dehydrogenase 1 (EC 1.2.1.36) (RalDH1) (RALDH 1)|
           (Aldehyde dehydrogenase family 1 member A1) (Aldehyde
           dehydrogenase, cytosolic) (ALHDII) (ALDH-E1)
          Length = 500

 Score = 30.0 bits (66), Expect = 4.7
 Identities = 20/60 (33%), Positives = 29/60 (48%), Gaps = 2/60 (3%)
 Frame = +3

Query: 291 SRTIDNMEGMRDGIFGDIHKLMSVLEFDDVSQ--FNSFYDFVFFISRENGQKNITVQKAL 464
           S   D+M   ++ IFG + ++M     DDV +   N+FY     I   +  K ITV  AL
Sbjct: 387 SDVTDDMRIAKEEIFGPVQQIMKFKSLDDVIKRANNTFYGLSAGIFTNDIDKAITVSSAL 446

>AL1A1_BOVIN (P48644) Retinal dehydrogenase 1 (EC 1.2.1.36) (RalDH1) (RALDH 1)|
           (Aldehyde dehydrogenase family 1 member A1) (Aldehyde
           dehydrogenase, cytosolic) (ALHDII) (ALDH-E1)
          Length = 500

 Score = 30.0 bits (66), Expect = 4.7
 Identities = 20/60 (33%), Positives = 29/60 (48%), Gaps = 2/60 (3%)
 Frame = +3

Query: 291 SRTIDNMEGMRDGIFGDIHKLMSVLEFDDVSQ--FNSFYDFVFFISRENGQKNITVQKAL 464
           S   D+M   ++ IFG + ++M     DDV +   N+FY     I   +  K ITV  AL
Sbjct: 387 SDVTDDMRIAKEEIFGPVQQIMKFKSLDDVIKRANNTFYGLSAGIFTNDIDKAITVSSAL 446

>TRXR2_HUMAN (Q9NNW7) Thioredoxin reductase 2, mitochondrial precursor (EC|
           1.8.1.9) (TR3) (TR-beta) (Selenoprotein Z) (SelZ)
          Length = 524

 Score = 29.6 bits (65), Expect = 6.1
 Identities = 16/28 (57%), Positives = 19/28 (67%), Gaps = 1/28 (3%)
 Frame = +2

Query: 152 HGSAHGIQRLRGC-PSRVPRRRPGLLQV 232
           H ++HG + LRGC PSRV R   G LQV
Sbjct: 267 HMASHGTRFLRGCAPSRVRRLPDGQLQV 294


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 68,496,739
Number of Sequences: 219361
Number of extensions: 1249353
Number of successful extensions: 2940
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 2864
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2940
length of database: 80,573,946
effective HSP length: 106
effective length of database: 57,321,680
effective search space used: 4643056080
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)