ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | bart32e06 |
|---|---|
| Clone Library Name | barley_pub |
>SAPK3_ORYSA (Q75V63) Serine/threonine-protein kinase SAPK3 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 3) (Protein kinase REK) Length = 334 Score = 293 bits (751), Expect = 1e-79 Identities = 146/174 (83%), Positives = 157/174 (90%) Frame = +2 Query: 2 LDGSPTPRVKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTL 181 LDGSPTPRVKICDFGYSKSALLHSKPK TVGTPAYIAPEVLSRKEYDGKVADVWSCGVTL Sbjct: 132 LDGSPTPRVKICDFGYSKSALLHSKPKSTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTL 191 Query: 182 YVMLIGSYPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRIT 361 YVML+GSYPFEDP DPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIF ADPSKRIT Sbjct: 192 YVMLVGSYPFEDPGDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFVADPSKRIT 251 Query: 362 IAEIKKLPWYLKSLPKEIAERDRANFKEPEKATETAASAAQPVEEIMRIIQEGQ 523 I EIKK W+LK+LPKEI+ER++A++K+ + AA Q VEEIMRIIQE + Sbjct: 252 IPEIKKHTWFLKNLPKEISEREKADYKDTD-----AAPPTQAVEEIMRIIQEAK 300
>SAPK7_ORYSA (Q7XQP4) Serine/threonine-protein kinase SAPK7 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 7) Length = 359 Score = 255 bits (651), Expect = 6e-68 Identities = 118/174 (67%), Positives = 147/174 (84%) Frame = +2 Query: 2 LDGSPTPRVKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTL 181 LDGSP PR+KICDFGYSKS+LLHSKPK TVGTPAYIAPEVLSR+EYDGK ADVWSCGVTL Sbjct: 131 LDGSPAPRLKICDFGYSKSSLLHSKPKSTVGTPAYIAPEVLSRREYDGKTADVWSCGVTL 190 Query: 182 YVMLIGSYPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRIT 361 YVML+G+YPFEDP+DP+NFRKTI RI+ +QY IP+YV VS DCR+LLS+IF A+P+KRIT Sbjct: 191 YVMLVGAYPFEDPDDPKNFRKTIGRIMSIQYKIPEYVHVSQDCRQLLSRIFVANPAKRIT 250 Query: 362 IAEIKKLPWYLKSLPKEIAERDRANFKEPEKATETAASAAQPVEEIMRIIQEGQ 523 I EI+ PW+LK+LP+E+ E +A + + + + T + Q VEEIM+I++E + Sbjct: 251 IREIRNHPWFLKNLPRELTEAAQAMYYKKDNSAPT--YSVQSVEEIMKIVEEAR 302
>SAPK6_ORYSA (Q6ZI44) Serine/threonine-protein kinase SAPK6 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 6) Length = 365 Score = 255 bits (651), Expect = 6e-68 Identities = 116/174 (66%), Positives = 148/174 (85%) Frame = +2 Query: 2 LDGSPTPRVKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTL 181 LDGSP PR+KICDFGYSKS+LLHSKPK TVGTPAYIAPEVLSR+EYDGK+ADVWSCGVTL Sbjct: 131 LDGSPAPRLKICDFGYSKSSLLHSKPKSTVGTPAYIAPEVLSRREYDGKMADVWSCGVTL 190 Query: 182 YVMLIGSYPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRIT 361 YVML+G+YPFEDP+DP+NFRKTI RI+ +QY IP+YV +S DCR+LLS+IF A+P+KRIT Sbjct: 191 YVMLVGAYPFEDPDDPKNFRKTIGRIVSIQYKIPEYVHISQDCRQLLSRIFVANPAKRIT 250 Query: 362 IAEIKKLPWYLKSLPKEIAERDRANFKEPEKATETAASAAQPVEEIMRIIQEGQ 523 I EI+ PW++K+LP+E+ E +A + + + + T + Q V+EIM+I+QE + Sbjct: 251 IREIRNHPWFMKNLPRELTEAAQAKYYKKDNSARTFSD--QTVDEIMKIVQEAK 302
>SAPK5_ORYSA (Q7XKA8) Serine/threonine-protein kinase SAPK5 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 5) Length = 370 Score = 253 bits (647), Expect = 2e-67 Identities = 124/184 (67%), Positives = 150/184 (81%), Gaps = 10/184 (5%) Frame = +2 Query: 2 LDGSPTPRVKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTL 181 LDGSP PR+KICDFGYSKS+LLHS+PK TVGTPAYIAPEVLSR+EYDGK+ADVWSCGVTL Sbjct: 131 LDGSPAPRLKICDFGYSKSSLLHSRPKSTVGTPAYIAPEVLSRREYDGKLADVWSCGVTL 190 Query: 182 YVMLIGSYPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRIT 361 YVML+G+YPFEDP+DP+NFRKTISRI+ VQY IP+YV VS CR LLS+IF A+P KRI+ Sbjct: 191 YVMLVGAYPFEDPKDPKNFRKTISRIMSVQYKIPEYVHVSQPCRHLLSRIFVANPYKRIS 250 Query: 362 IAEIKKLPWYLKSLPKEIAERDRA---NFKEPEKATETAASAA-------QPVEEIMRII 511 + EIK PW+LK+LP+E+ E +A N + + A +A+SAA Q VE+IMRI+ Sbjct: 251 MGEIKSHPWFLKNLPRELKEEAQAVYYNRRGADHAASSASSAAAAAAFSPQSVEDIMRIV 310 Query: 512 QEGQ 523 QE Q Sbjct: 311 QEAQ 314
>SAPK1_ORYSA (Q75LR7) Serine/threonine-protein kinase SAPK1 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 1) Length = 342 Score = 250 bits (638), Expect = 2e-66 Identities = 121/174 (69%), Positives = 145/174 (83%) Frame = +2 Query: 2 LDGSPTPRVKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTL 181 LDGS TPR+KICDFGYSKS++LHS+PK TVGTPAYIAPEVLSRKEYDGKVADVWSCGVTL Sbjct: 131 LDGSVTPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTL 190 Query: 182 YVMLIGSYPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRIT 361 YVML+G+YPFEDP+DPRNFRKTI+RIL VQYSIPDYVRVS+DCR LLS+IF +P +RIT Sbjct: 191 YVMLVGAYPFEDPDDPRNFRKTITRILSVQYSIPDYVRVSADCRHLLSRIFVGNPEQRIT 250 Query: 362 IAEIKKLPWYLKSLPKEIAERDRANFKEPEKATETAASAAQPVEEIMRIIQEGQ 523 I EIK PW+LK+LP E+ + + + + + T +Q +EE+M IIQE + Sbjct: 251 IPEIKNHPWFLKNLPIEMTDEYQRSMQLADMNT-----PSQSLEEVMAIIQEAR 299
>ASK1_ARATH (P43291) Serine/threonine-protein kinase ASK1 (EC 2.7.11.1)| Length = 363 Score = 246 bits (627), Expect = 4e-65 Identities = 117/174 (67%), Positives = 143/174 (82%) Frame = +2 Query: 2 LDGSPTPRVKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTL 181 LDGSP PR+KICDFGYSKS+LLHS+PK TVGTPAYIAPEVLSR+EYDGK+ADVWSCGVTL Sbjct: 131 LDGSPAPRLKICDFGYSKSSLLHSRPKSTVGTPAYIAPEVLSRREYDGKMADVWSCGVTL 190 Query: 182 YVMLIGSYPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRIT 361 YVML+G+YPFED EDP+NFRKTI +I+ VQY IPDYV +S DC+ LLS+IF A+ KRIT Sbjct: 191 YVMLVGAYPFEDQEDPKNFRKTIQKIMAVQYKIPDYVHISQDCKNLLSRIFVANSLKRIT 250 Query: 362 IAEIKKLPWYLKSLPKEIAERDRANFKEPEKATETAASAAQPVEEIMRIIQEGQ 523 IAEIKK W+LK+LP+E+ E +A + + E T + Q VEEIM+I+ + + Sbjct: 251 IAEIKKHSWFLKNLPRELTETAQAAYFKKENPT----FSLQTVEEIMKIVADAK 300
>SAPK2_ORYSA (Q84TC6) Serine/threonine-protein kinase SAPK2 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 2) Length = 339 Score = 242 bits (617), Expect = 5e-64 Identities = 118/174 (67%), Positives = 143/174 (82%) Frame = +2 Query: 2 LDGSPTPRVKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTL 181 LDGS PR+KICDFGYSKS+LLHS+PK TVGTPAYIAPEVL+RKEYDGKVADVWSCGVTL Sbjct: 131 LDGSIAPRLKICDFGYSKSSLLHSQPKSTVGTPAYIAPEVLARKEYDGKVADVWSCGVTL 190 Query: 182 YVMLIGSYPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRIT 361 YVML+G+YPFEDP++PRNFRKTI+RIL VQY +PDYVRVS +CR LLS+IF A+P +RIT Sbjct: 191 YVMLVGAYPFEDPDEPRNFRKTITRILSVQYMVPDYVRVSMECRHLLSRIFVANPEQRIT 250 Query: 362 IAEIKKLPWYLKSLPKEIAERDRANFKEPEKATETAASAAQPVEEIMRIIQEGQ 523 I EIK PW+LK+LP E+ + + + + + T +Q +EEIM IIQE + Sbjct: 251 IPEIKNHPWFLKNLPIEMTDEYQMSVQMNDINT-----PSQGLEEIMAIIQEAR 299
>AAIP_WHEAT (Q02066) Abscisic acid-inducible protein kinase (EC 2.7.11.1)| (Fragment) Length = 332 Score = 241 bits (614), Expect = 1e-63 Identities = 117/174 (67%), Positives = 140/174 (80%) Frame = +2 Query: 2 LDGSPTPRVKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTL 181 LDGS PR+KICDFGYSKS++LHS+PK TVGTPAYIAPEVLSR+EYDGKVADVWSCGVTL Sbjct: 121 LDGSVAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTL 180 Query: 182 YVMLIGSYPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRIT 361 YVML+G+YPFEDP++PRNFRKTI+RIL VQYS+PDYVRVS DC LLS+IF +P +RIT Sbjct: 181 YVMLVGAYPFEDPDEPRNFRKTITRILSVQYSVPDYVRVSMDCIHLLSRIFVGNPQQRIT 240 Query: 362 IAEIKKLPWYLKSLPKEIAERDRANFKEPEKATETAASAAQPVEEIMRIIQEGQ 523 I EIK PW+LK LP E+ + + + + + T +Q +EE M IIQE Q Sbjct: 241 IPEIKNHPWFLKRLPVEMTDEYQRSMQLADMNT-----PSQSLEEAMAIIQEAQ 289
>ASK2_ARATH (P43292) Serine/threonine-protein kinase ASK2 (EC 2.7.11.1)| Length = 353 Score = 239 bits (609), Expect = 4e-63 Identities = 112/174 (64%), Positives = 140/174 (80%) Frame = +2 Query: 2 LDGSPTPRVKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTL 181 LDGSP P +KICDFGYSKS++LHS+PK TVGTPAYIAPEVLSR+EYDGK ADVWSCGVTL Sbjct: 131 LDGSPAPLLKICDFGYSKSSILHSRPKSTVGTPAYIAPEVLSRREYDGKHADVWSCGVTL 190 Query: 182 YVMLIGSYPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRIT 361 YVML+G+YPFEDP DP+NFRKTI RI+ VQY IPDYV +S +C+ LLS+IF + +KRIT Sbjct: 191 YVMLVGAYPFEDPNDPKNFRKTIQRIMAVQYKIPDYVHISQECKHLLSRIFVTNSAKRIT 250 Query: 362 IAEIKKLPWYLKSLPKEIAERDRANFKEPEKATETAASAAQPVEEIMRIIQEGQ 523 + EIK PWYLK+LPKE+ E +A + + + + + Q VE+IM+I+ E + Sbjct: 251 LKEIKNHPWYLKNLPKELLESAQAAYYKRD-----TSFSLQSVEDIMKIVGEAR 299
>SAPK4_ORYSA (Q5N942) Serine/threonine-protein kinase SAPK4 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 4) Length = 360 Score = 235 bits (599), Expect = 6e-62 Identities = 107/174 (61%), Positives = 142/174 (81%) Frame = +2 Query: 2 LDGSPTPRVKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTL 181 LDGSP PR+KICDFGYSKS++LHS+PK VGTPAYIAPEVLSR+EYDGK+ADVWSCGVTL Sbjct: 131 LDGSPAPRLKICDFGYSKSSVLHSRPKSAVGTPAYIAPEVLSRREYDGKLADVWSCGVTL 190 Query: 182 YVMLIGSYPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRIT 361 YVML+G+YPFED +DP+N RKTI RI+ VQY IPDYV +S++C++L+++IF +P +RIT Sbjct: 191 YVMLVGAYPFEDQDDPKNIRKTIQRIMSVQYKIPDYVHISAECKQLIARIFVNNPLRRIT 250 Query: 362 IAEIKKLPWYLKSLPKEIAERDRANFKEPEKATETAASAAQPVEEIMRIIQEGQ 523 + EIK PW+LK+LP+E+ E +A + + + + + Q EEIM+I+QE + Sbjct: 251 MKEIKSHPWFLKNLPRELTETAQAMYYRRDNSVPSFSD--QTSEEIMKIVQEAR 302
>SAPKA_ORYSA (Q75H77) Serine/threonine-protein kinase SAPK10 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 10) Length = 362 Score = 234 bits (596), Expect = 1e-61 Identities = 109/174 (62%), Positives = 143/174 (82%), Gaps = 2/174 (1%) Frame = +2 Query: 2 LDGSPTPRVKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTL 181 LDGS PR+KICDFGYSKS++LHS+PK TVGTPAYIAPEVL +KEYDGK+ADVWSCGVTL Sbjct: 150 LDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYDGKIADVWSCGVTL 209 Query: 182 YVMLIGSYPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRIT 361 YVML+G+YPFEDP++P+NFRKTI RILGVQYSIPDYV +S +CR L+++IF A+P+ RI+ Sbjct: 210 YVMLVGAYPFEDPDEPKNFRKTIQRILGVQYSIPDYVHISPECRDLIARIFVANPATRIS 269 Query: 362 IAEIKKLPWYLKSLPKEIAERDR--ANFKEPEKATETAASAAQPVEEIMRIIQE 517 I EI+ PW+LK+LP ++ + + + ++EPE+ Q ++EIM+I+ E Sbjct: 270 IPEIRNHPWFLKNLPADLMDDSKMSSQYEEPEQ-------PMQSMDEIMQILAE 316
>SAPK9_ORYSA (Q75V57) Serine/threonine-protein kinase SAPK9 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 9) Length = 361 Score = 230 bits (587), Expect = 2e-60 Identities = 107/174 (61%), Positives = 140/174 (80%), Gaps = 2/174 (1%) Frame = +2 Query: 2 LDGSPTPRVKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTL 181 LDGS PR+KICDFGYSKS++LHS+PK TVGTPAYIAPEVL +KEYDGK+ADVWSCGVTL Sbjct: 149 LDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYDGKIADVWSCGVTL 208 Query: 182 YVMLIGSYPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRIT 361 YVML+G+YPFEDPEDP+NFRKTI +ILGVQYSIPDYV +S +CR L+++IF +P+ RIT Sbjct: 209 YVMLVGAYPFEDPEDPKNFRKTIQKILGVQYSIPDYVHISPECRDLITRIFVGNPASRIT 268 Query: 362 IAEIKKLPWYLKSLPKEIAERDRAN--FKEPEKATETAASAAQPVEEIMRIIQE 517 + EIK PW++K++P ++ + + ++EP++ Q + EIM+I+ E Sbjct: 269 MPEIKNHPWFMKNIPADLMDDGMVSNQYEEPDQ-------PMQNMNEIMQILAE 315
>SAPK8_ORYSA (Q7Y0B9) Serine/threonine-protein kinase SAPK8 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 8) Length = 371 Score = 229 bits (583), Expect = 5e-60 Identities = 108/174 (62%), Positives = 140/174 (80%), Gaps = 2/174 (1%) Frame = +2 Query: 2 LDGSPTPRVKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTL 181 LDGSP PR+KICDFGYSKS++LHS+PK TVGTPAYIAPEVL +KEYDGK ADVWSCGVTL Sbjct: 160 LDGSPAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYDGKTADVWSCGVTL 219 Query: 182 YVMLIGSYPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRIT 361 YVM++G+YPFEDPE+P+NFRKTI RIL VQYSIP+ V +S +CR L+S+IF DPS RIT Sbjct: 220 YVMVVGAYPFEDPEEPKNFRKTIQRILNVQYSIPENVDISPECRHLISRIFVGDPSLRIT 279 Query: 362 IAEIKKLPWYLKSLPKEIAERD--RANFKEPEKATETAASAAQPVEEIMRIIQE 517 I EI+ W+LK+LP ++ + D + ++EP++ +T +++IM+I+ E Sbjct: 280 IPEIRSHGWFLKNLPADLMDDDSMSSQYEEPDQPMQT-------MDQIMQILTE 326
>KIN10_ARATH (Q38997) SNF1-related protein kinase catalytic alpha subunit KIN10| (EC 2.7.11.1) (AKIN10) (AKIN alpha2) Length = 535 Score = 102 bits (254), Expect = 6e-22 Identities = 58/146 (39%), Positives = 81/146 (55%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSY 205 VKI DFG S K + G+P Y APEV+S K Y G DVWSCGV LY +L G+ Sbjct: 179 VKIADFGLSNIMRDGHFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYALLCGTL 238 Query: 206 PFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLP 385 PF+D P F+K I G Y++P + +S R L+ ++ DP KR+TI EI++ P Sbjct: 239 PFDDENIPNLFKK----IKGGIYTLPSH--LSPGARDLIPRMLVVDPMKRVTIPEIRQHP 292 Query: 386 WYLKSLPKEIAERDRANFKEPEKATE 463 W+ LP+ +A ++ +K E Sbjct: 293 WFQAHLPRYLAVPPPDTVQQAKKIDE 318
>KIN11_ARATH (P92958) SNF1-related protein kinase catalytic alpha subunit KIN11| (EC 2.7.11.1) (AKIN11) (AKIN alpha1) Length = 512 Score = 102 bits (253), Expect = 8e-22 Identities = 58/146 (39%), Positives = 82/146 (56%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSY 205 +KI DFG S K + G+P Y APEV+S K Y G DVWSCGV LY +L G+ Sbjct: 157 IKIADFGLSNVMRDGHFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYALLCGTL 216 Query: 206 PFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLP 385 PF+D P F+K I G Y++P + +SS+ R L+ ++ DP KRITI EI++ Sbjct: 217 PFDDENIPNLFKK----IKGGIYTLPSH--LSSEARDLIPRMLIVDPVKRITIPEIRQHR 270 Query: 386 WYLKSLPKEIAERDRANFKEPEKATE 463 W+ LP+ +A ++ +K E Sbjct: 271 WFQTHLPRYLAVSPPDTVEQAKKINE 296
>SNF1_SCHPO (O74536) SNF1-like protein kinase ssp2 (EC 2.7.11.1)| Length = 576 Score = 102 bits (253), Expect = 8e-22 Identities = 55/127 (43%), Positives = 77/127 (60%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSY 205 VKI DFG S + K + G+P Y APEV++ K Y G DVWSCG+ LYVML+G Sbjct: 170 VKIADFGLSNIMTDGNFLKTSCGSPNYAAPEVINGKLYAGPEVDVWSCGIVLYVMLVGRL 229 Query: 206 PFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLP 385 PF+D P F+K S + Y +PD+ +S + L+ ++ ADP +RITI EI++ P Sbjct: 230 PFDDEFIPNLFKKVNSCV----YVMPDF--LSPGAQSLIRRMIVADPMQRITIQEIRRDP 283 Query: 386 WYLKSLP 406 W+ +LP Sbjct: 284 WFNVNLP 290
>CPK11_ARATH (O22932) CBL-interacting serine/threonine-protein kinase 11 (EC| 2.7.11.1) (SOS2-like protein kinase PKS5) (SOS-interacting protein 4) (SNF1-related kinase 3.22) Length = 435 Score = 97.8 bits (242), Expect = 2e-20 Identities = 55/141 (39%), Positives = 79/141 (56%), Gaps = 7/141 (4%) Frame = +2 Query: 26 VKICDFGYSK-------SALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLY 184 +K+ DFG S LLH+ GTPAY+APE+LS+K Y+G DVWSCG+ L+ Sbjct: 159 LKVSDFGLSALTDQIRPDGLLHT----LCGTPAYVAPEILSKKGYEGAKVDVWSCGIVLF 214 Query: 185 VMLIGSYPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITI 364 V++ G PF DP N +I +Y P + +S D +R +S++ +P RITI Sbjct: 215 VLVAGYLPFNDP----NVMNMYKKIYKGEYRFPRW--MSPDLKRFVSRLLDINPETRITI 268 Query: 365 AEIKKLPWYLKSLPKEIAERD 427 EI K PW+++ K+I D Sbjct: 269 DEILKDPWFVRGGFKQIKFHD 289
>RKIN1_SECCE (Q02723) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 502 Score = 97.1 bits (240), Expect = 3e-20 Identities = 57/131 (43%), Positives = 74/131 (56%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSY 205 VK+ DFG S K + G+ Y APEV+S K Y G DVWSCGV LY +L G+ Sbjct: 154 VKLADFGLSNVMHDGHFLKTSCGSLNYAAPEVISGKLYAGPEIDVWSCGVILYALLCGAV 213 Query: 206 PFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLP 385 PF+D P F+K I G Y +P Y +S R L+S++ DP KRITI EI+K Sbjct: 214 PFDDDNIPNLFKK----IKGGTYILPIY--LSDLVRDLISRMLIVDPMKRITIGEIRKHS 267 Query: 386 WYLKSLPKEIA 418 W+ LP+ +A Sbjct: 268 WFQNRLPRYLA 278
>CPK15_ARATH (P92937) CBL-interacting serine/threonine-protein kinase 15 (EC| 2.7.11.1) (Serine/threonine-protein kinase ATPK10) (SOS2-like protein kinase PKS3) (SOS-interacting protein 2) (SNF1-related kinase 3.1) Length = 421 Score = 96.3 bits (238), Expect = 5e-20 Identities = 60/158 (37%), Positives = 85/158 (53%), Gaps = 7/158 (4%) Frame = +2 Query: 26 VKICDFGYS-------KSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLY 184 +KI DFG S + LLH+ T GTPAY+APEV+SR YDG ADVWSCGV L+ Sbjct: 148 LKISDFGLSALSDSRRQDGLLHT----TCGTPAYVAPEVISRNGYDGFKADVWSCGVILF 203 Query: 185 VMLIGSYPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITI 364 V+L G PF D N + +I + P++ ++ +RLL +I +P+ R++ Sbjct: 204 VLLAGYLPFRD----SNLMELYKKIGKAEVKFPNW--LAPGAKRLLKRILDPNPNTRVST 257 Query: 365 AEIKKLPWYLKSLPKEIAERDRANFKEPEKATETAASA 478 +I K W+ K L +E+ E E+ TE A A Sbjct: 258 EKIMKSSWFRKGLQEEVKE-------SVEEETEVDAEA 288
>CIPK1_ORYSA (Q6X4A2) CIPK-like protein 1 (EC 2.7.11.1) (OsCK1)| Length = 449 Score = 95.5 bits (236), Expect = 8e-20 Identities = 56/152 (36%), Positives = 84/152 (55%), Gaps = 8/152 (5%) Frame = +2 Query: 26 VKICDFGYSK-------SALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLY 184 +K+ DFG S LLH+ T GTP Y+APEV+ + YDG AD+WSCGV LY Sbjct: 157 LKVSDFGLSALTEQVKADGLLHT----TCGTPNYVAPEVIEDRGYDGAAADIWSCGVILY 212 Query: 185 VMLIGSYPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITI 364 V+L G PFED N +I Q++ P + S+ ++L+++I +P+ RITI Sbjct: 213 VLLAGFLPFEDD----NIIALYKKISEAQFTCPSW--FSTGAKKLITRILDPNPTTRITI 266 Query: 365 AEIKKLPWYLKSL-PKEIAERDRANFKEPEKA 457 ++I + PW+ K P E+ +F + + A Sbjct: 267 SQILEDPWFKKGYKPPVFDEKYETSFDDVDAA 298
>MARK2_RAT (O08679) Serine/threonine-protein kinase MARK2 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 2) (ELKL Motif Kinase) (EMK1) Length = 722 Score = 95.1 bits (235), Expect = 1e-19 Identities = 61/170 (35%), Positives = 86/170 (50%), Gaps = 12/170 (7%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSY 205 +KI DFG+S +K G+P Y APE+ K+YDG DVWS GV LY ++ GS Sbjct: 189 IKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSL 248 Query: 206 PFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLP 385 PF D +N ++ R+L +Y IP Y +S+DC LL + +PSKR T+ +I K Sbjct: 249 PF----DGQNLKELRERVLRGKYRIPFY--MSTDCENLLKKFLILNPSKRGTLEQIMKDR 302 Query: 386 W------------YLKSLPKEIAERDRANFKEPEKATETAASAAQPVEEI 499 W Y++ LP ++K+P + TE S EEI Sbjct: 303 WMNVGHEDDELKPYVEPLP---------DYKDPRR-TELMVSMGYTREEI 342
>MARK2_HUMAN (Q7KZI7) Serine/threonine-protein kinase MARK2 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 2) (ELKL motif kinase) (EMK1) (PAR1 homolog) Length = 788 Score = 95.1 bits (235), Expect = 1e-19 Identities = 61/170 (35%), Positives = 86/170 (50%), Gaps = 12/170 (7%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSY 205 +KI DFG+S +K G+P Y APE+ K+YDG DVWS GV LY ++ GS Sbjct: 189 IKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSL 248 Query: 206 PFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLP 385 PF D +N ++ R+L +Y IP Y +S+DC LL + +PSKR T+ +I K Sbjct: 249 PF----DGQNLKELRERVLRGKYRIPFY--MSTDCENLLKKFLILNPSKRGTLEQIMKDR 302 Query: 386 W------------YLKSLPKEIAERDRANFKEPEKATETAASAAQPVEEI 499 W Y++ LP ++K+P + TE S EEI Sbjct: 303 WMNVGHEDDELKPYVEPLP---------DYKDPRR-TELMVSMGYTREEI 342
>BRSK1_HUMAN (Q8TDC3) BR serine/threonine-protein kinase 1 (EC 2.7.11.1) (SAD1| kinase) (SAD1A) Length = 794 Score = 94.7 bits (234), Expect = 1e-19 Identities = 43/123 (34%), Positives = 76/123 (61%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSY 205 ++I DFG + + S + + G+P Y PEV+ ++YDG+ AD+WSCGV L+ +L+G+ Sbjct: 186 IRIADFGMASLQVGDSLLETSCGSPHYACPEVIKGEKYDGRRADMWSCGVILFALLVGAL 245 Query: 206 PFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLP 385 PF+D N R+ + ++ + +P + + DC+ LL + +P KR+++ +I+K P Sbjct: 246 PFDDD----NLRQLLEKVKRGVFHMPHF--IPPDCQSLLRGMIEVEPEKRLSLEQIQKHP 299 Query: 386 WYL 394 WYL Sbjct: 300 WYL 302
>MARK4_MOUSE (Q8CIP4) MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1)| Length = 752 Score = 94.4 bits (233), Expect = 2e-19 Identities = 48/121 (39%), Positives = 69/121 (57%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSY 205 +KI DFG+S L SK G+P Y APE+ K+YDG D+WS GV LY ++ GS Sbjct: 195 IKIADFGFSNEFTLGSKLDTFCGSPPYAAPELFQGKKYDGPEVDIWSLGVILYTLVSGSL 254 Query: 206 PFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLP 385 PF D N ++ R+L +Y +P Y +S+DC +L + +P+KR T+ +I K Sbjct: 255 PF----DGHNLKELRERVLRGKYRVPFY--MSTDCESILRRFLVLNPAKRCTLEQIMKDK 308 Query: 386 W 388 W Sbjct: 309 W 309
>MARK4_HUMAN (Q96L34) MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase-like 1) Length = 752 Score = 94.4 bits (233), Expect = 2e-19 Identities = 48/121 (39%), Positives = 69/121 (57%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSY 205 +KI DFG+S L SK G+P Y APE+ K+YDG D+WS GV LY ++ GS Sbjct: 195 IKIADFGFSNEFTLGSKLDTFCGSPPYAAPELFQGKKYDGPEVDIWSLGVILYTLVSGSL 254 Query: 206 PFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLP 385 PF D N ++ R+L +Y +P Y +S+DC +L + +P+KR T+ +I K Sbjct: 255 PF----DGHNLKELRERVLRGKYRVPFY--MSTDCESILRRFLVLNPAKRCTLEQIMKDK 308 Query: 386 W 388 W Sbjct: 309 W 309
>SN1L1_MOUSE (Q60670) Serine/threonine-protein kinase SNF1-like kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase SNF1LK) (HRT-20) (Myocardial SNF1-like kinase) Length = 779 Score = 93.6 bits (231), Expect = 3e-19 Identities = 49/121 (40%), Positives = 69/121 (57%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSY 205 +K+ DFG+ VG+P Y APEV KEY+G DVWS GV LYV++ GS Sbjct: 163 IKLADFGFGNFYKPGEPLSTCVGSPPYAAPEVFEGKEYEGPQLDVWSLGVVLYVLVCGSL 222 Query: 206 PFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLP 385 PF+ P N R+L ++ IP + +S DC L+ ++ DP+KRITIA+I++ Sbjct: 223 PFDGP----NLPTLRQRVLEGRFRIPFF--MSQDCETLIRRMLVVDPAKRITIAQIRQHR 276 Query: 386 W 388 W Sbjct: 277 W 277
>MARK3_MOUSE (Q03141) MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1)| (MPK-10) (ELKL motif kinase 2) Length = 753 Score = 93.2 bits (230), Expect = 4e-19 Identities = 50/121 (41%), Positives = 69/121 (57%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSY 205 +KI DFG+S + SK G+P Y APE+ K+YDG DVWS GV LY ++ GS Sbjct: 192 IKIADFGFSNEFTVGSKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSL 251 Query: 206 PFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLP 385 PF D +N ++ R+L +Y IP Y +S+DC LL + +P KR T+ +I K Sbjct: 252 PF----DGQNLKELRERVLRGKYRIPFY--MSTDCENLLKRFLVLNPVKRGTLEQIMKDR 305 Query: 386 W 388 W Sbjct: 306 W 306
>MARK3_RAT (Q8VHF0) MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1)| Length = 797 Score = 93.2 bits (230), Expect = 4e-19 Identities = 55/142 (38%), Positives = 76/142 (53%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSY 205 +KI DFG+S + SK G+P Y APE+ K+YDG DVWS GV LY ++ GS Sbjct: 192 IKITDFGFSNEFTVGSKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSL 251 Query: 206 PFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLP 385 PF D +N ++ R+L +Y IP Y +S+DC LL + +P KR T+ +I K Sbjct: 252 PF----DGQNLKELRERVLRGKYRIPFY--MSTDCENLLKRFLVLNPVKRGTLEQIMKDR 305 Query: 386 WYLKSLPKEIAERDRANFKEPE 451 W + E + F EPE Sbjct: 306 W----INAGHEEEELKPFVEPE 323
>AAPK2_RAT (Q09137) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMPK alpha-2 chain) Length = 552 Score = 93.2 bits (230), Expect = 4e-19 Identities = 58/167 (34%), Positives = 81/167 (48%), Gaps = 3/167 (1%) Frame = +2 Query: 29 KICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSYP 208 KI DFG S + + G+P Y APEV+S + Y G D+WSCGV LY +L G+ P Sbjct: 154 KIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSCGVILYALLCGTLP 213 Query: 209 FEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLPW 388 F+D P F+K I G + IP+Y+ S LL + DP KR TI +I++ W Sbjct: 214 FDDEHVPTLFKK----IRGGVFYIPEYLNRS--IATLLMHMLQVDPLKRATIKDIREHEW 267 Query: 389 YLKSLPKEIAERD---RANFKEPEKATETAASAAQPVEEIMRIIQEG 520 + + LP + D AN + E E E+M + G Sbjct: 268 FKQDLPSYLFPEDPSYDANVIDDEAVKEVCEKFECTESEVMNSLYSG 314
>AAPK2_PIG (Q28948) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMPK alpha-2 chain) Length = 552 Score = 93.2 bits (230), Expect = 4e-19 Identities = 58/167 (34%), Positives = 81/167 (48%), Gaps = 3/167 (1%) Frame = +2 Query: 29 KICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSYP 208 KI DFG S + + G+P Y APEV+S + Y G D+WSCGV LY +L G+ P Sbjct: 154 KIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSCGVILYALLCGTLP 213 Query: 209 FEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLPW 388 F+D P F+K I G + IP+Y+ S LL + DP KR TI +I++ W Sbjct: 214 FDDEHVPTLFKK----IRGGVFYIPEYLNRS--VATLLMHMLQVDPLKRATIKDIREHEW 267 Query: 389 YLKSLPKEIAERD---RANFKEPEKATETAASAAQPVEEIMRIIQEG 520 + + LP + D AN + E E E+M + G Sbjct: 268 FKQDLPSYLFPEDPSYDANVIDDEAVKEVCEKFECTESEVMNSLYSG 314
>AAPK2_HUMAN (P54646) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMPK alpha-2 chain) Length = 552 Score = 93.2 bits (230), Expect = 4e-19 Identities = 58/167 (34%), Positives = 81/167 (48%), Gaps = 3/167 (1%) Frame = +2 Query: 29 KICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSYP 208 KI DFG S + + G+P Y APEV+S + Y G D+WSCGV LY +L G+ P Sbjct: 154 KIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSCGVILYALLCGTLP 213 Query: 209 FEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLPW 388 F+D P F+K I G + IP+Y+ S LL + DP KR TI +I++ W Sbjct: 214 FDDEHVPTLFKK----IRGGVFYIPEYLNRS--VATLLMHMLQVDPLKRATIKDIREHEW 267 Query: 389 YLKSLPKEIAERD---RANFKEPEKATETAASAAQPVEEIMRIIQEG 520 + + LP + D AN + E E E+M + G Sbjct: 268 FKQDLPSYLFPEDPSYDANVIDDEAVKEVCEKFECTESEVMNSLYSG 314
>SNF1_CANTR (O94168) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 619 Score = 93.2 bits (230), Expect = 4e-19 Identities = 54/139 (38%), Positives = 77/139 (55%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSY 205 VKI DFG S + K + G+P Y APEV+S K Y G DVWS GV LYVML G Sbjct: 188 VKIADFGLSNIMTDGNFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSSGVILYVMLCGRL 247 Query: 206 PFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLP 385 PF+D P F+K + + Y++P+Y +S + LL+++ +P RITI EI + Sbjct: 248 PFDDEFIPALFKKISNGV----YTLPNY--LSPGAKHLLTRMLVVNPLNRITIHEIMEDE 301 Query: 386 WYLKSLPKEIAERDRANFK 442 W+ + +P + D + K Sbjct: 302 WFKQDMPDYLLPPDLSKIK 320
>AAPK2_PONPY (Q5RD00) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMPK alpha-2 chain) Length = 552 Score = 92.8 bits (229), Expect = 5e-19 Identities = 58/167 (34%), Positives = 81/167 (48%), Gaps = 3/167 (1%) Frame = +2 Query: 29 KICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSYP 208 KI DFG S + + G+P Y APEV+S + Y G D+WSCGV LY +L G+ P Sbjct: 154 KIADFGLSNIMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSCGVILYALLCGTLP 213 Query: 209 FEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLPW 388 F+D P F+K I G + IP+Y+ S LL + DP KR TI +I++ W Sbjct: 214 FDDEHVPTLFKK----IRGGVFYIPEYLNRS--VATLLMHMLQVDPLKRATIKDIREHEW 267 Query: 389 YLKSLPKEIAERD---RANFKEPEKATETAASAAQPVEEIMRIIQEG 520 + + LP + D AN + E E E+M + G Sbjct: 268 FKQDLPSYLFPEDPSYDANVIDDEAVKEVCEKFECTESEVMNSLYSG 314
>MARK2_MOUSE (Q05512) Serine/threonine-protein kinase MARK2 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 2) (ELKL Motif Kinase) (EMK1) Length = 776 Score = 92.0 bits (227), Expect = 9e-19 Identities = 60/170 (35%), Positives = 85/170 (50%), Gaps = 12/170 (7%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSY 205 +KI DFG+S +K G+P Y APE+ K+ DG DVWS GV LY ++ GS Sbjct: 189 IKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKIDGPEVDVWSLGVILYTLVSGSL 248 Query: 206 PFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLP 385 PF D +N ++ R+L +Y IP Y +S+DC LL + +PSKR T+ +I K Sbjct: 249 PF----DGQNLKELRERVLRGKYRIPFY--MSTDCENLLKKFLILNPSKRGTLEQIMKDR 302 Query: 386 W------------YLKSLPKEIAERDRANFKEPEKATETAASAAQPVEEI 499 W Y++ LP ++K+P + TE S EEI Sbjct: 303 WMNVGHEDDELKPYVEPLP---------DYKDPRR-TELMVSMGYTREEI 342
>MARK3_HUMAN (P27448) MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1)| (Cdc25C-associated protein kinase 1) (cTAK1) (C-TAK1) (Serine/threonine protein kinase p78) (Ser/Thr protein kinase PAR-1) (Protein kinase STK10) Length = 776 Score = 91.7 bits (226), Expect = 1e-18 Identities = 49/121 (40%), Positives = 68/121 (56%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSY 205 +KI DFG+S + K G+P Y APE+ K+YDG DVWS GV LY ++ GS Sbjct: 215 IKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSL 274 Query: 206 PFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLP 385 PF D +N ++ R+L +Y IP Y +S+DC LL + +P KR T+ +I K Sbjct: 275 PF----DGQNLKELRERVLRGKYRIPFY--MSTDCENLLKRFLVLNPIKRGTLEQIMKDR 328 Query: 386 W 388 W Sbjct: 329 W 329
>MARK1_HUMAN (Q9P0L2) Serine/threonine-protein kinase MARK1 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 1) Length = 795 Score = 91.7 bits (226), Expect = 1e-18 Identities = 51/129 (39%), Positives = 73/129 (56%) Frame = +2 Query: 2 LDGSPTPRVKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTL 181 LDG +KI DFG+S + +K G+P Y APE+ K+YDG DVWS GV L Sbjct: 190 LDGDMN--IKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVIL 247 Query: 182 YVMLIGSYPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRIT 361 Y ++ GS PF D +N ++ R+L +Y IP Y +S+DC LL ++ +P KR + Sbjct: 248 YTLVSGSLPF----DGQNLKELRERVLRGKYRIPFY--MSTDCENLLKKLLVLNPIKRGS 301 Query: 362 IAEIKKLPW 388 + +I K W Sbjct: 302 LEQIMKDRW 310
>SN1L1_RAT (Q9R1U5) Serine/threonine-protein kinase SNF1-like kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase SNF1LK) (Salt-inducible protein kinase) (Protein kinase KID2) Length = 776 Score = 91.3 bits (225), Expect = 1e-18 Identities = 50/129 (38%), Positives = 72/129 (55%) Frame = +2 Query: 2 LDGSPTPRVKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTL 181 LDG+ +K+ DFG+ G+P Y APEV KEY+G D+WS GV L Sbjct: 157 LDGNMD--IKLADFGFGNFYKPGEPLSTWCGSPPYAAPEVFEGKEYEGPQLDIWSLGVVL 214 Query: 182 YVMLIGSYPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRIT 361 YV++ GS PF+ P N R+L ++ IP + +S DC L+ ++ DP+KRIT Sbjct: 215 YVLVCGSLPFDGP----NLPTLRQRVLEGRFRIPFF--MSQDCETLIRRMLVVDPAKRIT 268 Query: 362 IAEIKKLPW 388 IA+I++ W Sbjct: 269 IAQIRQHRW 277
>KKK1_YEAST (P34244) Probable serine/threonine-protein kinase YKL101W (EC| 2.7.11.1) Length = 1518 Score = 91.3 bits (225), Expect = 1e-18 Identities = 47/121 (38%), Positives = 70/121 (57%) Frame = +2 Query: 23 RVKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGS 202 R+KI DFG + L + K + G+P Y +PE++ + Y G +DVWSCG+ L+ +L G Sbjct: 253 RIKIADFGMAALELPNKLLKTSCGSPHYASPEIVMGRPYHGGPSDVWSCGIVLFALLTGH 312 Query: 203 YPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKL 382 PF D N +K + ++ +Y +P +SS+ R L+S+I DP KRIT EI K Sbjct: 313 LPFNDD----NIKKLLLKVQSGKYQMPS--NLSSEARDLISKILVIDPEKRITTQEILKH 366 Query: 383 P 385 P Sbjct: 367 P 367
>SN1L2_CHICK (Q9IA88) Serine/threonine-protein kinase SNF1-like kinase 2 (EC| 2.7.11.1) (Qin-induced kinase) Length = 798 Score = 91.3 bits (225), Expect = 1e-18 Identities = 47/121 (38%), Positives = 68/121 (56%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSY 205 +K+ DFG+ G+P Y APEV KEY+G D+WS GV LYV++ GS Sbjct: 162 IKLADFGFGNFYKSGEPLSTWCGSPPYAAPEVFEGKEYEGPHLDIWSLGVVLYVLVCGSL 221 Query: 206 PFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLP 385 PF+ P N R+L ++ IP + +S DC L+ ++ DP+KRITI++IK+ Sbjct: 222 PFDGP----NLPTLRQRVLEGRFRIPYF--MSEDCETLIRRMLVVDPTKRITISQIKQHK 275 Query: 386 W 388 W Sbjct: 276 W 276
>MARK1_MOUSE (Q8VHJ5) Serine/threonine-protein kinase MARK1 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 1) (ELKL motif serine/threonine-protein kinase 3) Length = 795 Score = 90.9 bits (224), Expect = 2e-18 Identities = 47/121 (38%), Positives = 70/121 (57%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSY 205 +KI DFG+S + +K G+P Y APE+ K+YDG DVWS GV LY ++ GS Sbjct: 196 IKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSL 255 Query: 206 PFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLP 385 PF D +N ++ R+L +Y +P Y +S+DC LL ++ +P KR ++ +I K Sbjct: 256 PF----DGQNLKELRERVLRGKYRVPFY--MSTDCENLLKKLLVLNPIKRGSLEQIMKDR 309 Query: 386 W 388 W Sbjct: 310 W 310
>SN1L2_HUMAN (Q9H0K1) Serine/threonine-protein kinase SNF1-like kinase 2 (EC| 2.7.11.1) (Qin-induced kinase) Length = 926 Score = 90.9 bits (224), Expect = 2e-18 Identities = 48/127 (37%), Positives = 71/127 (55%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSY 205 +KI DFG+ G+P Y APEV ++Y+G D+WS GV LYV++ G+ Sbjct: 156 IKIADFGFGNFFKSGELLATWCGSPPYAAPEVFEGQQYEGPQLDIWSMGVVLYVLVCGAL 215 Query: 206 PFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLP 385 PF+ P P R+L ++ IP + +S DC L+ ++ DPSKR+TIA+IK+ Sbjct: 216 PFDGPTLP----ILRQRVLEGRFRIPYF--MSEDCEHLIRRMLVLDPSKRLTIAQIKEHK 269 Query: 386 WYLKSLP 406 W L +P Sbjct: 270 WMLIEVP 276
>CPK24_ARATH (Q9LDI3) CBL-interacting serine/threonine-protein kinase 24 (EC| 2.7.11.1) (SNF1-related kinase 3.11) (SALT OVERLY SENSITIVE 2 protein) Length = 446 Score = 90.9 bits (224), Expect = 2e-18 Identities = 56/144 (38%), Positives = 80/144 (55%), Gaps = 4/144 (2%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKP---KPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLI 196 +K+ DFG S AL + T GTP Y+APEVLS + YDG AD+WSCGV L+V+L Sbjct: 148 LKVSDFGLS--ALPQEGVELLRTTCGTPNYVAPEVLSGQGYDGSAADIWSCGVILFVILA 205 Query: 197 GSYPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIK 376 G PF + + P +RK I ++S P + S++ + L+ +I +P RI I IK Sbjct: 206 GYLPFSETDLPGLYRK----INAAEFSCPPW--FSAEVKFLIHRILDPNPKTRIQIQGIK 259 Query: 377 KLPWY-LKSLPKEIAERDRANFKE 445 K PW+ L +P E + N + Sbjct: 260 KDPWFRLNYVPIRAREEEEVNLDD 283
>MARK1_RAT (O08678) Serine/threonine-protein kinase MARK1 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 1) Length = 793 Score = 90.9 bits (224), Expect = 2e-18 Identities = 47/121 (38%), Positives = 70/121 (57%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSY 205 +KI DFG+S + +K G+P Y APE+ K+YDG DVWS GV LY ++ GS Sbjct: 196 IKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSL 255 Query: 206 PFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLP 385 PF D +N ++ R+L +Y +P Y +S+DC LL ++ +P KR ++ +I K Sbjct: 256 PF----DGQNLKELRERVLRGKYRVPFY--MSTDCENLLKKLLVLNPIKRGSLEQIMKDR 309 Query: 386 W 388 W Sbjct: 310 W 310
>SN1L1_HUMAN (P57059) Serine/threonine-protein kinase SNF1-like kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase SNF1LK) Length = 783 Score = 90.5 bits (223), Expect = 3e-18 Identities = 49/129 (37%), Positives = 72/129 (55%) Frame = +2 Query: 2 LDGSPTPRVKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTL 181 LDG+ +K+ DFG+ G+P Y APEV KEY+G D+WS GV L Sbjct: 157 LDGNMD--IKLADFGFGNFYKSGEPLSTWCGSPPYAAPEVFEGKEYEGPQLDIWSLGVVL 214 Query: 182 YVMLIGSYPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRIT 361 YV++ GS PF+ P N R+L ++ IP + +S DC L+ ++ DP++RIT Sbjct: 215 YVLVCGSLPFDGP----NLPTLRQRVLEGRFRIPFF--MSQDCESLIRRMLVVDPARRIT 268 Query: 362 IAEIKKLPW 388 IA+I++ W Sbjct: 269 IAQIRQHRW 277
>SN1L2_MOUSE (Q8CFH6) Serine/threonine-protein kinase SNF1-like kinase 2 (EC| 2.7.11.1) (Salt-inducible kinase 2) Length = 931 Score = 89.7 bits (221), Expect = 4e-18 Identities = 47/127 (37%), Positives = 71/127 (55%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSY 205 +KI DFG+ G+P Y APEV ++Y+G D+WS GV LYV++ G+ Sbjct: 156 IKIADFGFGNFFKTGELLATWCGSPPYAAPEVFEGQQYEGPQLDIWSMGVVLYVLVCGAL 215 Query: 206 PFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLP 385 PF+ P P R+L ++ IP + +S DC L+ ++ DPSKR++IA+IK+ Sbjct: 216 PFDGPTLP----ILRQRVLEGRFRIPYF--MSEDCEHLIRRMLVLDPSKRLSIAQIKEHK 269 Query: 386 WYLKSLP 406 W L +P Sbjct: 270 WMLIEVP 276
>SNRK_MOUSE (Q8VDU5) SNF-related serine/threonine-protein kinase (EC 2.7.11.1)| (SNF1-related kinase) Length = 748 Score = 89.4 bits (220), Expect = 6e-18 Identities = 44/121 (36%), Positives = 72/121 (59%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSY 205 VK+ DFG+S K + G+ AY APE+L EYD D+WS GV L++++ G Sbjct: 154 VKLTDFGFSNKFQPGKKLTTSCGSLAYSAPEILLGDEYDAPAVDIWSLGVILFMLVCGQP 213 Query: 206 PFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLP 385 PF++ D +T++ I+ +Y++P RVS+ CR L++++ DP +R ++ EI+ P Sbjct: 214 PFQEAND----SETLTMIMDCKYTVPP--RVSAGCRDLITRMLQRDPKRRASLEEIESHP 267 Query: 386 W 388 W Sbjct: 268 W 268
>SNF1_CANAL (P52497) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 620 Score = 89.4 bits (220), Expect = 6e-18 Identities = 54/140 (38%), Positives = 79/140 (56%), Gaps = 1/140 (0%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTVGTPAYI-APEVLSRKEYDGKVADVWSCGVTLYVMLIGS 202 VKI DFG S + K + G+P Y+ APEV+S K Y G DVWS GV LYVML G Sbjct: 189 VKIADFGLSNIMTDGNFLKTSCGSPNYMPAPEVISGKLYAGPEVDVWSAGVILYVMLCGR 248 Query: 203 YPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKL 382 PF+D P F+K + + Y++P+Y +S+ + LL+++ +P RITI EI + Sbjct: 249 LPFDDEFIPALFKKISNGV----YTLPNY--LSAGAKHLLTRMLVVNPLNRITIHEIMED 302 Query: 383 PWYLKSLPKEIAERDRANFK 442 W+ + +P + D + K Sbjct: 303 DWFKQDMPDYLLPPDLSKNK 322
>SNRK_RAT (Q63553) SNF-related serine/threonine-protein kinase (EC 2.7.11.1)| (SNF1-related kinase) Length = 746 Score = 89.4 bits (220), Expect = 6e-18 Identities = 44/121 (36%), Positives = 72/121 (59%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSY 205 VK+ DFG+S K + G+ AY APE+L EYD D+WS GV L++++ G Sbjct: 154 VKLTDFGFSNKFQPGKKLTTSCGSLAYSAPEILLGDEYDAPAVDIWSLGVILFMLVCGQP 213 Query: 206 PFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLP 385 PF++ D +T++ I+ +Y++P RVS+ CR L++++ DP +R ++ EI+ P Sbjct: 214 PFQEAND----SETLTMIMDCKYTVPP--RVSAGCRDLITRMLQRDPKRRASLEEIESHP 267 Query: 386 W 388 W Sbjct: 268 W 268
>BRSK2_HUMAN (Q8IWQ3) BR serine/threonine-protein kinase 2 (EC 2.7.11.1)| (Serine/threonine-protein kinase 29) (SAD1B) Length = 736 Score = 89.0 bits (219), Expect = 7e-18 Identities = 42/123 (34%), Positives = 74/123 (60%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSY 205 ++I DFG + + S + + G+P Y PEV+ ++YDG+ ADVWSCGV L+ +L+G+ Sbjct: 155 IRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLVGAL 214 Query: 206 PFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLP 385 PF+D N R+ + ++ + +P + + DC+ LL + D ++R+T+ I+K Sbjct: 215 PFDDD----NLRQLLEKVKRGVFHMPHF--IPPDCQSLLRGMSEVDAARRLTLEHIQKHI 268 Query: 386 WYL 394 WY+ Sbjct: 269 WYI 271
>AAPK2_CAEEL (Q95ZQ4) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMP-activated kinase 2) Length = 626 Score = 88.6 bits (218), Expect = 1e-17 Identities = 51/127 (40%), Positives = 66/127 (51%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSY 205 VKI DFG S + + G+P Y APEV+S K Y G DVWSCGV LY +L G+ Sbjct: 224 VKIADFGLSNIMTDGDFLRTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYALLCGTL 283 Query: 206 PFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLP 385 PF+D P FRK S + + PD+ + LL + DP KR TI ++ Sbjct: 284 PFDDEHVPSLFRKIKSGV----FPTPDF--LERPIVNLLHHMLCVDPMKRATIKDVIAHE 337 Query: 386 WYLKSLP 406 W+ K LP Sbjct: 338 WFQKDLP 344
>IPL1_ASHGO (Q755C4) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 367 Score = 88.6 bits (218), Expect = 1e-17 Identities = 48/127 (37%), Positives = 74/127 (58%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSY 205 +K+ DFG+S SK K GT Y++PE++ +EY+ KV DVW+ GV Y +L+GS Sbjct: 246 IKLTDFGWSVITPKGSKRKTLCGTVDYLSPELIRSREYNEKV-DVWALGVLTYELLVGSP 304 Query: 206 PFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLP 385 PFE+ +++ + R L PD+V ++ R L+S++ DP RI + E+KK P Sbjct: 305 PFEEESKELTYKRILKRNL----IFPDHV--DTEARHLISRLLEYDPGDRIPLKEVKKHP 358 Query: 386 WYLKSLP 406 W K+ P Sbjct: 359 WIEKNKP 365
>SNRK_HUMAN (Q9NRH2) SNF-related serine/threonine-protein kinase (EC 2.7.11.1)| (SNF1-related kinase) Length = 765 Score = 88.2 bits (217), Expect = 1e-17 Identities = 42/121 (34%), Positives = 72/121 (59%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSY 205 VK+ DFG+S K + G+ AY APE+L EYD D+WS GV L++++ G Sbjct: 154 VKLTDFGFSNKFQPGKKLTTSCGSLAYSAPEILLGDEYDAPAVDIWSLGVILFMLVCGQP 213 Query: 206 PFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLP 385 PF++ D +T++ I+ +Y++P + VS +C+ L++++ DP +R ++ EI+ P Sbjct: 214 PFQEAND----SETLTMIMDCKYTVPSH--VSKECKDLITRMLQRDPKRRASLEEIENHP 267 Query: 386 W 388 W Sbjct: 268 W 268
>SN1L2_PONPY (Q5REX1) Serine/threonine-protein kinase SNF1-like kinase 2 (EC| 2.7.11.1) Length = 925 Score = 87.8 bits (216), Expect = 2e-17 Identities = 47/127 (37%), Positives = 70/127 (55%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSY 205 +KI DF + G+P Y APEV ++Y+G D+WS GV LYV++ G+ Sbjct: 156 IKIADFSFGNFFKSGELLATWRGSPPYAAPEVFEGQQYEGPQLDIWSMGVVLYVLVCGAL 215 Query: 206 PFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLP 385 PF+ P P R+L ++ IP + +S DC L+ ++ DPSKR+TIA+IK+ Sbjct: 216 PFDGPTLP----ILRQRVLEGRFRIPYF--MSEDCEHLIRRMLVLDPSKRLTIAQIKEHK 269 Query: 386 WYLKSLP 406 W L +P Sbjct: 270 WMLIEVP 276
>KCC2A_DROME (Q00168) Calcium/calmodulin-dependent protein kinase type II alpha| chain (EC 2.7.11.17) (CaM-kinase II alpha chain) Length = 530 Score = 86.7 bits (213), Expect = 4e-17 Identities = 46/122 (37%), Positives = 71/122 (58%), Gaps = 1/122 (0%) Frame = +2 Query: 26 VKICDFGYSKSALL-HSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGS 202 VK+ DFG + H GTP Y++PEVL ++ Y GK D+W+CGV LY++L+G Sbjct: 153 VKLADFGLAIEVQGDHQAWFGFAGTPGYLSPEVLKKEPY-GKSVDIWACGVILYILLVGY 211 Query: 203 YPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKL 382 PF D + R + + + Y P++ V+ + + L++Q+ T +P+KRIT AE K Sbjct: 212 PPFWDEDQHRLYSQI--KAGAYDYPSPEWDTVTPEAKNLINQMLTVNPNKRITAAEALKH 269 Query: 383 PW 388 PW Sbjct: 270 PW 271
>CIPK1_ARATH (Q8RWC9) CBL-interacting serine/threonine-protein kinase 1 (EC| 2.7.11.1) (SOS2-like protein kinase PKS13) (SNF1-related kinase 3.16) Length = 444 Score = 86.7 bits (213), Expect = 4e-17 Identities = 58/169 (34%), Positives = 83/169 (49%), Gaps = 15/169 (8%) Frame = +2 Query: 26 VKICDFGYSK-------SALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLY 184 +KI DFG S LLH+ T G+P Y+APEVL+ + YDG +D+WSCGV LY Sbjct: 157 IKITDFGLSALPQHFRDDGLLHT----TCGSPNYVAPEVLANRGYDGAASDIWSCGVILY 212 Query: 185 VMLIGSYPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITI 364 V+L G PF+D RN +I IP + +S R ++ ++ +P RIT+ Sbjct: 213 VILTGCLPFDD----RNLAVLYQKICKGDPPIPRW--LSPGARTMIKRMLDPNPVTRITV 266 Query: 365 AEIKKLPW----YLKSLP----KEIAERDRANFKEPEKATETAASAAQP 487 IK W Y+ S+P +E + D F E +E + P Sbjct: 267 VGIKASEWFKLEYIPSIPDDDDEEEVDTDDDAFSIQELGSEEGKGSDSP 315
>AAPK1_PONPY (Q5RDH5) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMPK alpha-1 chain) Length = 550 Score = 85.5 bits (210), Expect = 8e-17 Identities = 50/133 (37%), Positives = 70/133 (52%) Frame = +2 Query: 29 KICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSYP 208 KI DFG S + + G+P Y APEV+S + Y G D+WS GV LY +L G+ P Sbjct: 156 KIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLP 215 Query: 209 FEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLPW 388 F+D P F+K G+ Y+ P Y+ S LL + DP KR TI +I++ W Sbjct: 216 FDDDHVPTLFKKICD---GIFYT-PQYLNPS--VISLLKHMLQVDPMKRATIKDIREHEW 269 Query: 389 YLKSLPKEIAERD 427 + + LPK + D Sbjct: 270 FKQDLPKYLFPED 282
>AAPK1_HUMAN (Q13131) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMPK alpha-1 chain) Length = 550 Score = 85.5 bits (210), Expect = 8e-17 Identities = 50/133 (37%), Positives = 70/133 (52%) Frame = +2 Query: 29 KICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSYP 208 KI DFG S + + G+P Y APEV+S + Y G D+WS GV LY +L G+ P Sbjct: 156 KIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLP 215 Query: 209 FEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLPW 388 F+D P F+K G+ Y+ P Y+ S LL + DP KR TI +I++ W Sbjct: 216 FDDDHVPTLFKKICD---GIFYT-PQYLNPS--VISLLKHMLQVDPMKRATIKDIREHEW 269 Query: 389 YLKSLPKEIAERD 427 + + LPK + D Sbjct: 270 FKQDLPKYLFPED 282
>KIN1_SCHPO (P22987) Protein kinase kin1 (EC 2.7.11.1)| Length = 891 Score = 85.5 bits (210), Expect = 8e-17 Identities = 58/170 (34%), Positives = 85/170 (50%), Gaps = 5/170 (2%) Frame = +2 Query: 11 SPTPRVKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVM 190 S T +KI DFG S S+ + G+ + APE+L+ + Y G DVWS G+ LYV+ Sbjct: 275 SKTGDIKIIDFGLSNLYRRQSRLRTFCGSLYFAAPELLNAQPYIGPEVDVWSFGIVLYVL 334 Query: 191 LIGSYPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAE 370 + G PF+D +N ++I P Y +SSDC+ LLS++ DP KR T+ E Sbjct: 335 VCGKVPFDD----QNMSALHAKIKKGTVEYPSY--LSSDCKGLLSRMLVTDPLKRATLEE 388 Query: 371 IKKLPWYLKSL---PKEIA-ERDRANFK-EPEKATETAASAAQPVEEIMR 505 + PW +++ P A ER +PE E P E+I+R Sbjct: 389 VLNHPWMIRNYEGPPASFAPERSPITLPLDPEIIREMNGFDFGPPEKIVR 438
>AAPK1_RAT (P54645) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMPK alpha-1 chain) Length = 548 Score = 85.5 bits (210), Expect = 8e-17 Identities = 50/133 (37%), Positives = 70/133 (52%) Frame = +2 Query: 29 KICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSYP 208 KI DFG S + + G+P Y APEV+S + Y G D+WS GV LY +L G+ P Sbjct: 154 KIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLP 213 Query: 209 FEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLPW 388 F+D P F+K G+ Y+ P Y+ S LL + DP KR TI +I++ W Sbjct: 214 FDDDHVPTLFKKICD---GIFYT-PQYLNPS--VISLLKHMLQVDPMKRATIKDIREHEW 267 Query: 389 YLKSLPKEIAERD 427 + + LPK + D Sbjct: 268 FKQDLPKYLFPED 280
>SNF1_YEAST (P06782) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 633 Score = 84.7 bits (208), Expect = 1e-16 Identities = 52/142 (36%), Positives = 73/142 (51%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSY 205 VKI DFG S + K + G+P Y APEV+S K Y G DVWSCGV LYVML Sbjct: 191 VKIADFGLSNIMTDGNFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYVMLCRRL 250 Query: 206 PFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLP 385 PF+D P F+ + + Y++P + +S L+ ++ +P RI+I EI + Sbjct: 251 PFDDESIPVLFKNISNGV----YTLPKF--LSPGAAGLIKRMLIVNPLNRISIHEIMQDD 304 Query: 386 WYLKSLPKEIAERDRANFKEPE 451 W+ LP+ + D E E Sbjct: 305 WFKVDLPEYLLPPDLKPHPEEE 326
>SNF1_CANGA (Q00372) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 612 Score = 83.6 bits (205), Expect = 3e-16 Identities = 55/158 (34%), Positives = 83/158 (52%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSY 205 VKI DFG S + K + G+P Y APEV+S K Y G DVWSCGV LYVML Sbjct: 175 VKIADFGLSNIMTDGNFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYVMLCRRL 234 Query: 206 PFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLP 385 PF+D P F+ + + Y++P + +S L+ ++ +P RI+I EI + Sbjct: 235 PFDDESIPVLFKNISNGV----YTLPKF--LSPGASDLIKRMLIVNPLNRISIHEIMQDE 288 Query: 386 WYLKSLPKEIAERDRANFKEPEKATETAASAAQPVEEI 499 W+ L + + +D K+ E+ + + + + VEEI Sbjct: 289 WFKVDLAEYLVPQD---LKQQEQFNKKSGN-EENVEEI 322
>AAPK1_MOUSE (Q5EG47) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMPK alpha-1 chain) Length = 548 Score = 83.6 bits (205), Expect = 3e-16 Identities = 49/133 (36%), Positives = 69/133 (51%) Frame = +2 Query: 29 KICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSYP 208 KI DFG S + + G+P Y APEV+S + Y G D+WS GV LY +L G+ P Sbjct: 154 KIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLP 213 Query: 209 FEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLPW 388 F+D P F+K G+ Y+ P Y+ S LL + DP KR I +I++ W Sbjct: 214 FDDDHVPTLFKKICD---GIFYT-PQYLNPS--VISLLKHMLQVDPMKRAAIKDIREHEW 267 Query: 389 YLKSLPKEIAERD 427 + + LPK + D Sbjct: 268 FKQDLPKYLFPED 280
>KCC2A_MOUSE (P11798) Calcium/calmodulin-dependent protein kinase type II alpha| chain (EC 2.7.11.17) (CaM-kinase II alpha chain) (CaM kinase II alpha subunit) (CaMK-II alpha subunit) Length = 478 Score = 83.2 bits (204), Expect = 4e-16 Identities = 40/99 (40%), Positives = 64/99 (64%) Frame = +2 Query: 92 GTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSYPFEDPEDPRNFRKTISRILGVQ 271 GTP Y++PEVL + Y GK D+W+CGV LY++L+G PF D + R +++ +R Sbjct: 175 GTPGYLSPEVLRKDPY-GKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAR--AYD 231 Query: 272 YSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLPW 388 + P++ V+ + + L++++ T +PSKRIT AE K PW Sbjct: 232 FPSPEWDTVTPEAKDLINKMLTINPSKRITAAEALKHPW 270
>KCC4_YEAST (P25389) Probable serine/threonine-protein kinase KCC4 (EC| 2.7.11.1) Length = 1037 Score = 82.4 bits (202), Expect = 7e-16 Identities = 42/120 (35%), Positives = 67/120 (55%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSY 205 +KI DFG + + + G+P Y APE++S Y+G +DVWSCGV L+ +L G Sbjct: 166 IKIADFGMAALQTDADLLETSCGSPHYAAPEIVSGLPYEGFASDVWSCGVILFALLTGRL 225 Query: 206 PFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLP 385 PF+ E+ N R + ++ Q+ +P+ +S D + L+ +I DP +RI I +I P Sbjct: 226 PFD--EENGNVRDLLLKVQKGQFEMPNDTEISRDAQDLIGKILVVDPRQRIKIRDILSHP 283
>TRIB2_PONPY (Q5R669) Tribbles homolog 2 (TRB-2)| Length = 343 Score = 82.0 bits (201), Expect = 9e-16 Identities = 44/101 (43%), Positives = 60/101 (59%), Gaps = 1/101 (0%) Frame = +2 Query: 92 GTPAYIAPEVLSRK-EYDGKVADVWSCGVTLYVMLIGSYPFEDPEDPRNFRKTISRILGV 268 G PAY++PE+L+ Y GK ADVWS GV LY ML+G YPF D E F S+I Sbjct: 214 GCPAYVSPEILNTSGSYSGKAADVWSLGVMLYTMLVGRYPFHDIEPSSLF----SKIRRG 269 Query: 269 QYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLPWY 391 Q++IP+ + + C L+ I +PS+R+T EI PW+ Sbjct: 270 QFNIPETLSPKAKC--LIRSILRREPSERLTSQEILDHPWF 308
>TRIB2_MOUSE (Q8K4K3) Tribbles homolog 2 (TRB-2)| Length = 343 Score = 82.0 bits (201), Expect = 9e-16 Identities = 44/101 (43%), Positives = 60/101 (59%), Gaps = 1/101 (0%) Frame = +2 Query: 92 GTPAYIAPEVLSRK-EYDGKVADVWSCGVTLYVMLIGSYPFEDPEDPRNFRKTISRILGV 268 G PAY++PE+L+ Y GK ADVWS GV LY ML+G YPF D E F S+I Sbjct: 214 GCPAYVSPEILNTSGSYSGKAADVWSLGVMLYTMLVGRYPFHDIEPSSLF----SKIRRG 269 Query: 269 QYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLPWY 391 Q++IP+ + + C L+ I +PS+R+T EI PW+ Sbjct: 270 QFNIPETLSPKAKC--LIRSILRREPSERLTSQEILDHPWF 308
>TRIB2_HUMAN (Q92519) Tribbles homolog 2 (TRB-2)| Length = 343 Score = 82.0 bits (201), Expect = 9e-16 Identities = 44/101 (43%), Positives = 60/101 (59%), Gaps = 1/101 (0%) Frame = +2 Query: 92 GTPAYIAPEVLSRK-EYDGKVADVWSCGVTLYVMLIGSYPFEDPEDPRNFRKTISRILGV 268 G PAY++PE+L+ Y GK ADVWS GV LY ML+G YPF D E F S+I Sbjct: 214 GCPAYVSPEILNTSGSYSGKAADVWSLGVMLYTMLVGRYPFHDIEPSSLF----SKIRRG 269 Query: 269 QYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLPWY 391 Q++IP+ + + C L+ I +PS+R+T EI PW+ Sbjct: 270 QFNIPETLSPKAKC--LIRSILRREPSERLTSQEILDHPWF 308
>TRIB2_CANFA (Q28283) Tribbles homolog 2 (TRB-2)| Length = 343 Score = 82.0 bits (201), Expect = 9e-16 Identities = 44/101 (43%), Positives = 60/101 (59%), Gaps = 1/101 (0%) Frame = +2 Query: 92 GTPAYIAPEVLSRK-EYDGKVADVWSCGVTLYVMLIGSYPFEDPEDPRNFRKTISRILGV 268 G PAY++PE+L+ Y GK ADVWS GV LY ML+G YPF D E F S+I Sbjct: 214 GCPAYVSPEILNTSGSYSGKAADVWSLGVMLYTMLVGRYPFHDIEPSSLF----SKIRRG 269 Query: 269 QYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLPWY 391 Q++IP+ + + C L+ I +PS+R+T EI PW+ Sbjct: 270 QFNIPETLSPKAKC--LIRSILRREPSERLTSQEILDHPWF 308
>TRIB2_BOVIN (Q5GLH2) Tribbles homolog 2 (TRB-2)| Length = 343 Score = 82.0 bits (201), Expect = 9e-16 Identities = 44/101 (43%), Positives = 60/101 (59%), Gaps = 1/101 (0%) Frame = +2 Query: 92 GTPAYIAPEVLSRK-EYDGKVADVWSCGVTLYVMLIGSYPFEDPEDPRNFRKTISRILGV 268 G PAY++PE+L+ Y GK ADVWS GV LY ML+G YPF D E F S+I Sbjct: 214 GCPAYVSPEILNTNGSYSGKAADVWSLGVMLYTMLVGRYPFHDIEPSSLF----SKIRRG 269 Query: 269 QYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLPWY 391 Q++IP+ + + C L+ I +PS+R+T EI PW+ Sbjct: 270 QFNIPETLSPKAKC--LIRSILRREPSERLTSQEILDHPWF 308
>KKCC2_RAT (O88831) Calcium/calmodulin-dependent protein kinase kinase 2 (EC| 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-kinase kinase beta) (CaM-KK beta) (CaMKK beta) Length = 587 Score = 81.3 bits (199), Expect = 2e-15 Identities = 55/169 (32%), Positives = 81/169 (47%), Gaps = 7/169 (4%) Frame = +2 Query: 26 VKICDFGYSKS-----ALLHSKPKPTVGTPAYIAPEVLS--RKEYDGKVADVWSCGVTLY 184 +KI DFG S ALL + TVGTPA++APE LS RK + GK DVW+ GVTLY Sbjct: 325 IKIADFGVSNEFKGSDALLSN----TVGTPAFMAPESLSETRKIFSGKALDVWAMGVTLY 380 Query: 185 VMLIGSYPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITI 364 + G PF D S+I PD ++ D + L++++ +P RI + Sbjct: 381 CFVFGQCPFMD----ERIMCLHSKIKSQALEFPDQPDIAEDLKDLITRMLDKNPESRIVV 436 Query: 365 AEIKKLPWYLKSLPKEIAERDRANFKEPEKATETAASAAQPVEEIMRII 511 EIK PW + + + D N E E ++ + + + +I Sbjct: 437 PEIKLHPWVTRHGAEPLPSEDE-NCTLVEVTEEEVENSVKHIPSLATVI 484
>KKCC2_MOUSE (Q8C078) Calcium/calmodulin-dependent protein kinase kinase 2 (EC| 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-kinase kinase beta) (CaM-KK beta) (CaMKK beta) Length = 588 Score = 81.3 bits (199), Expect = 2e-15 Identities = 55/169 (32%), Positives = 81/169 (47%), Gaps = 7/169 (4%) Frame = +2 Query: 26 VKICDFGYSKS-----ALLHSKPKPTVGTPAYIAPEVLS--RKEYDGKVADVWSCGVTLY 184 +KI DFG S ALL + TVGTPA++APE LS RK + GK DVW+ GVTLY Sbjct: 326 IKIADFGVSNEFKGSDALLSN----TVGTPAFMAPESLSETRKIFSGKALDVWAMGVTLY 381 Query: 185 VMLIGSYPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITI 364 + G PF D S+I PD ++ D + L++++ +P RI + Sbjct: 382 CFVFGQCPFMD----ERIMCLHSKIKSQALEFPDQPDIAEDLKDLITRMLDKNPESRIVV 437 Query: 365 AEIKKLPWYLKSLPKEIAERDRANFKEPEKATETAASAAQPVEEIMRII 511 EIK PW + + + D N E E ++ + + + +I Sbjct: 438 PEIKLHPWVTRHGAEPLPSEDE-NCTLVEVTEEEVENSVKHIPSLATVI 485
>KKCC2_HUMAN (Q96RR4) Calcium/calmodulin-dependent protein kinase kinase 2 (EC| 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-kinase kinase beta) (CaM-KK beta) (CaMKK beta) Length = 588 Score = 81.3 bits (199), Expect = 2e-15 Identities = 55/169 (32%), Positives = 81/169 (47%), Gaps = 7/169 (4%) Frame = +2 Query: 26 VKICDFGYSKS-----ALLHSKPKPTVGTPAYIAPEVLS--RKEYDGKVADVWSCGVTLY 184 +KI DFG S ALL + TVGTPA++APE LS RK + GK DVW+ GVTLY Sbjct: 326 IKIADFGVSNEFKGSDALLSN----TVGTPAFMAPESLSETRKIFSGKALDVWAMGVTLY 381 Query: 185 VMLIGSYPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITI 364 + G PF D S+I PD ++ D + L++++ +P RI + Sbjct: 382 CFVFGQCPFMD----ERIMCLHSKIKSQALEFPDQPDIAEDLKDLITRMLDKNPESRIVV 437 Query: 365 AEIKKLPWYLKSLPKEIAERDRANFKEPEKATETAASAAQPVEEIMRII 511 EIK PW + + + D N E E ++ + + + +I Sbjct: 438 PEIKLHPWVTRHGAEPLPSEDE-NCTLVEVTEEEVENSVKHIPSLATVI 485
>KCC2B_HUMAN (Q13554) Calcium/calmodulin-dependent protein kinase type II beta| chain (EC 2.7.11.17) (CaM-kinase II beta chain) (CaM kinase II beta subunit) (CaMK-II beta subunit) Length = 664 Score = 80.9 bits (198), Expect = 2e-15 Identities = 39/99 (39%), Positives = 63/99 (63%) Frame = +2 Query: 92 GTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSYPFEDPEDPRNFRKTISRILGVQ 271 GTP Y++PEVL RKE GK D+W+CGV LY++L+G PF D + + +++ + Sbjct: 176 GTPGYLSPEVL-RKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQI--KAGAYD 232 Query: 272 YSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLPW 388 + P++ V+ + + L++Q+ T +P+KRIT E K PW Sbjct: 233 FPSPEWDTVTPEAKNLINQMLTINPAKRITAHEALKHPW 271
>KCC2A_RAT (P11275) Calcium/calmodulin-dependent protein kinase type II alpha| chain (EC 2.7.11.17) (CaM-kinase II alpha chain) (CaM kinase II alpha subunit) (CaMK-II alpha subunit) Length = 478 Score = 80.9 bits (198), Expect = 2e-15 Identities = 39/99 (39%), Positives = 63/99 (63%) Frame = +2 Query: 92 GTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSYPFEDPEDPRNFRKTISRILGVQ 271 GTP Y++PEVL + Y GK D+W+CGV LY++L+G PF D + R +++ + Sbjct: 175 GTPGYLSPEVLRKDPY-GKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQI--KAGAYD 231 Query: 272 YSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLPW 388 + P++ V+ + + L++++ T +PSKRIT AE K PW Sbjct: 232 FPSPEWDTVTPEAKDLINKMLTINPSKRITAAEALKHPW 270
>KCC2A_PONPY (Q5RCC4) Calcium/calmodulin-dependent protein kinase type II alpha| chain (EC 2.7.11.17) (CaM-kinase II alpha chain) (CaM kinase II alpha subunit) (CaMK-II alpha subunit) Length = 478 Score = 80.9 bits (198), Expect = 2e-15 Identities = 39/99 (39%), Positives = 63/99 (63%) Frame = +2 Query: 92 GTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSYPFEDPEDPRNFRKTISRILGVQ 271 GTP Y++PEVL + Y GK D+W+CGV LY++L+G PF D + R +++ + Sbjct: 175 GTPGYLSPEVLRKDPY-GKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQI--KAGAYD 231 Query: 272 YSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLPW 388 + P++ V+ + + L++++ T +PSKRIT AE K PW Sbjct: 232 FPSPEWDTVTPEAKDLINKMLTINPSKRITAAEALKHPW 270
>KCC2A_HUMAN (Q9UQM7) Calcium/calmodulin-dependent protein kinase type II alpha| chain (EC 2.7.11.17) (CaM-kinase II alpha chain) (CaM kinase II alpha subunit) (CaMK-II alpha subunit) Length = 478 Score = 80.9 bits (198), Expect = 2e-15 Identities = 39/99 (39%), Positives = 63/99 (63%) Frame = +2 Query: 92 GTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSYPFEDPEDPRNFRKTISRILGVQ 271 GTP Y++PEVL + Y GK D+W+CGV LY++L+G PF D + R +++ + Sbjct: 175 GTPGYLSPEVLRKDPY-GKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQI--KAGAYD 231 Query: 272 YSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLPW 388 + P++ V+ + + L++++ T +PSKRIT AE K PW Sbjct: 232 FPSPEWDTVTPEAKDLINKMLTINPSKRITAAEALKHPW 270
>KCC2B_RAT (P08413) Calcium/calmodulin-dependent protein kinase type II beta| chain (EC 2.7.11.17) (CaM-kinase II beta chain) (CaM kinase II beta subunit) (CaMK-II beta subunit) Length = 542 Score = 80.9 bits (198), Expect = 2e-15 Identities = 39/99 (39%), Positives = 63/99 (63%) Frame = +2 Query: 92 GTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSYPFEDPEDPRNFRKTISRILGVQ 271 GTP Y++PEVL RKE GK D+W+CGV LY++L+G PF D + + +++ + Sbjct: 176 GTPGYLSPEVL-RKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQI--KAGAYD 232 Query: 272 YSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLPW 388 + P++ V+ + + L++Q+ T +P+KRIT E K PW Sbjct: 233 FPSPEWDTVTPEAKNLINQMLTINPAKRITAHEALKHPW 271
>KCC2B_MOUSE (P28652) Calcium/calmodulin-dependent protein kinase type II beta| chain (EC 2.7.11.17) (CaM-kinase II beta chain) (CaM kinase II beta subunit) (CaMK-II beta subunit) Length = 542 Score = 80.9 bits (198), Expect = 2e-15 Identities = 39/99 (39%), Positives = 63/99 (63%) Frame = +2 Query: 92 GTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSYPFEDPEDPRNFRKTISRILGVQ 271 GTP Y++PEVL RKE GK D+W+CGV LY++L+G PF D + + +++ + Sbjct: 176 GTPGYLSPEVL-RKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQI--KAGAYD 232 Query: 272 YSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLPW 388 + P++ V+ + + L++Q+ T +P+KRIT E K PW Sbjct: 233 FPSPEWDTVTPEAKNLINQMLTINPAKRITAHEALKHPW 271
>IPL1_CANGA (Q6FV07) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 358 Score = 80.9 bits (198), Expect = 2e-15 Identities = 45/127 (35%), Positives = 74/127 (58%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSY 205 VK+ DFG+S SK K GT Y++PE+++ +EYD +V DVW+ GV Y +++G Sbjct: 237 VKLADFGWSILNPEGSKRKTLCGTIDYLSPEMITPREYDEQV-DVWALGVLAYELVVGVP 295 Query: 206 PFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLP 385 PFE+ + T RIL + P+ +S D + L+S++ D ++R+++ +K P Sbjct: 296 PFEE----NSKELTYKRILKCDLNFPE--SISKDAKDLISKLLVTDTTQRLSLTGVKTHP 349 Query: 386 WYLKSLP 406 W LK+ P Sbjct: 350 WILKNKP 356
>MAPK2_HUMAN (P49137) MAP kinase-activated protein kinase 2 (EC 2.7.11.1)| (MAPK-activated protein kinase 2) (MAPKAP kinase 2) (MAPKAPK-2) (MK2) Length = 400 Score = 80.5 bits (197), Expect = 3e-15 Identities = 44/131 (33%), Positives = 69/131 (52%), Gaps = 2/131 (1%) Frame = +2 Query: 14 PTPRVKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVML 193 P +K+ DFG++K H+ TP Y+APEVL ++YD K D+WS GV +Y++L Sbjct: 199 PNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYD-KSCDMWSLGVIMYILL 257 Query: 194 IGSYPFEDPEDPRNFRKTISRILGVQYSI--PDYVRVSSDCRRLLSQIFTADPSKRITIA 367 G PF +RI QY P++ VS + + L+ + +P++R+TI Sbjct: 258 CGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTIT 317 Query: 368 EIKKLPWYLKS 400 E PW ++S Sbjct: 318 EFMNHPWIMQS 328
>MAPK2_CRILO (P49136) MAP kinase-activated protein kinase 2 (EC 2.7.11.1)| (MAPK-activated protein kinase 2) (MAPKAP kinase 2) (MAPKAPK-2) (P45-54 HSP27 kinase) (Fragment) Length = 329 Score = 80.5 bits (197), Expect = 3e-15 Identities = 44/131 (33%), Positives = 69/131 (52%), Gaps = 2/131 (1%) Frame = +2 Query: 14 PTPRVKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVML 193 P +K+ DFG++K H+ TP Y+APEVL ++YD K D+WS GV +Y++L Sbjct: 128 PNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYD-KSCDMWSLGVIMYILL 186 Query: 194 IGSYPFEDPEDPRNFRKTISRILGVQYSI--PDYVRVSSDCRRLLSQIFTADPSKRITIA 367 G PF +RI QY P++ VS + + L+ + +P++R+TI Sbjct: 187 CGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTIT 246 Query: 368 EIKKLPWYLKS 400 E PW ++S Sbjct: 247 EFMNHPWIMQS 257
>MAPK2_MOUSE (P49138) MAP kinase-activated protein kinase 2 (EC 2.7.11.1)| (MAPK-activated protein kinase 2) (MAPKAP kinase 2) (MAPKAPK-2) (MK2) Length = 386 Score = 80.5 bits (197), Expect = 3e-15 Identities = 44/131 (33%), Positives = 69/131 (52%), Gaps = 2/131 (1%) Frame = +2 Query: 14 PTPRVKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVML 193 P +K+ DFG++K H+ TP Y+APEVL ++YD K D+WS GV +Y++L Sbjct: 185 PNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYD-KSCDMWSLGVIMYILL 243 Query: 194 IGSYPFEDPEDPRNFRKTISRILGVQYSI--PDYVRVSSDCRRLLSQIFTADPSKRITIA 367 G PF +RI QY P++ VS + + L+ + +P++R+TI Sbjct: 244 CGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTIT 303 Query: 368 EIKKLPWYLKS 400 E PW ++S Sbjct: 304 EFMNHPWIMQS 314
>GIN4_YEAST (Q12263) Serine/threonine-protein kinase GIN4 (EC 2.7.11.1)| Length = 1142 Score = 80.5 bits (197), Expect = 3e-15 Identities = 41/120 (34%), Positives = 66/120 (55%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSY 205 +KI DFG + + + G+P Y APE++S Y G +DVWSCGV L+ +L G Sbjct: 170 IKIADFGMAALETEGKLLETSCGSPHYAAPEIVSGIPYQGFASDVWSCGVILFALLTGRL 229 Query: 206 PFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLP 385 PF+ E+ N R + ++ ++ +P +S + + L+ +I T DP +RI +I K P Sbjct: 230 PFD--EEDGNIRTLLLKVQKGEFEMPSDDEISREAQDLIRKILTVDPERRIKTRDILKHP 287
>KCC1A_HUMAN (Q14012) Calcium/calmodulin-dependent protein kinase type 1 (EC| 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha) Length = 370 Score = 80.1 bits (196), Expect = 3e-15 Identities = 52/175 (29%), Positives = 84/175 (48%), Gaps = 8/175 (4%) Frame = +2 Query: 23 RVKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGS 202 ++ I DFG SK S GTP Y+APEVL++K Y K D WS GV Y++L G Sbjct: 157 KIMISDFGLSKMEDPGSVLSTACGTPGYVAPEVLAQKPY-SKAVDCWSIGVIAYILLCGY 215 Query: 203 YPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKL 382 PF D D + F + + ++ P + +S + + + DP KR T + + Sbjct: 216 PPFYDENDAKLFEQILK--AEYEFDSPYWDDISDSAKDFIRHLMEKDPEKRFTCEQALQH 273 Query: 383 PWYL------KSLPKEIAERDRANF-KEPEKATETAASAAQPVEEI-MRIIQEGQ 523 PW K++ + ++E+ + NF K K A + + + ++ + QEGQ Sbjct: 274 PWIAGDTALDKNIHQSVSEQIKKNFAKSKWKQAFNATAVVRHMRKLQLGTSQEGQ 328
>IPL1_YARLI (Q6C3J2) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 371 Score = 80.1 bits (196), Expect = 3e-15 Identities = 46/127 (36%), Positives = 71/127 (55%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSY 205 +KI DFG+S A + + GT Y+ PE++ + YD V DVWS G+ +Y L G+ Sbjct: 236 IKISDFGWSVHAPSNRR-STLCGTMDYLPPEIVQSRPYDKNV-DVWSLGILMYEFLCGAP 293 Query: 206 PFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLP 385 PFE+P + T RI+ + IP YV S+D L+ ++ T DP+KR + ++ K P Sbjct: 294 PFEEPGGAQ---ATYRRIVKLDLRIPPYV--SADAADLIKRMLTLDPAKRFKLKDMHKHP 348 Query: 386 WYLKSLP 406 W ++ P Sbjct: 349 WIVRLRP 355
>DUN1_YEAST (P39009) DNA damage response protein kinase DUN1 (EC 2.7.11.1)| Length = 513 Score = 80.1 bits (196), Expect = 3e-15 Identities = 46/123 (37%), Positives = 65/123 (52%) Frame = +2 Query: 23 RVKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGS 202 +VKI DFG +K GTP+Y+APEVL++K Y KV D+WS GV LYV L G Sbjct: 360 QVKIADFGLAKFTGEMQFTNTLCGTPSYVAPEVLTKKGYTSKV-DLWSAGVILYVCLCGF 418 Query: 203 YPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKL 382 PF D P + ++ I + YS P + ++ L+S + +P +R I E Sbjct: 419 PPFSDQLGPPSLKEQILQAKYAFYS-PYWDKIDDSVLHLISNLLVLNPDERYNIDEALNH 477 Query: 383 PWY 391 PW+ Sbjct: 478 PWF 480
>TRIB1_HUMAN (Q96RU8) Tribbles homolog 1 (TRB-1) (SKIP1) (G-protein-coupled| receptor induced protein 2) (GIG-2) Length = 372 Score = 80.1 bits (196), Expect = 3e-15 Identities = 41/101 (40%), Positives = 60/101 (59%), Gaps = 1/101 (0%) Frame = +2 Query: 92 GTPAYIAPEVLSRK-EYDGKVADVWSCGVTLYVMLIGSYPFEDPEDPRNFRKTISRILGV 268 G PAY++PE+L+ Y GK ADVWS GV LY +L+G YPF D + F S+I Sbjct: 244 GCPAYVSPEILNTTGTYSGKAADVWSLGVMLYTLLVGRYPFHDSDPSALF----SKIRRG 299 Query: 269 QYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLPWY 391 Q+ IP+++ + C L+ + +PS+R+T EI PW+ Sbjct: 300 QFCIPEHISPKARC--LIRSLLRREPSERLTAPEILLHPWF 338
>AAPK1_CAEEL (P45894) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMP-activated kinase 1) Length = 589 Score = 80.1 bits (196), Expect = 3e-15 Identities = 47/127 (37%), Positives = 59/127 (46%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSY 205 +KI DFG S G+P Y APE++S K Y G D+WSCGV LY ML G+ Sbjct: 161 IKIADFGLSNYMTDGDLLSTACGSPNYAAPELISNKLYVGPEVDLWSCGVILYAMLCGTL 220 Query: 206 PFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLP 385 PF+D P F K S V YS + L+S + DP KR + I Sbjct: 221 PFDDQNVPTLFAKIKSGRYTVPYS------MEKQAADLISTMLQVDPVKRADVKRIVNHS 274 Query: 386 WYLKSLP 406 W+ LP Sbjct: 275 WFRIDLP 281
>KCC1A_RAT (Q63450) Calcium/calmodulin-dependent protein kinase type 1 (EC| 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha) Length = 374 Score = 80.1 bits (196), Expect = 3e-15 Identities = 52/175 (29%), Positives = 84/175 (48%), Gaps = 8/175 (4%) Frame = +2 Query: 23 RVKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGS 202 ++ I DFG SK S GTP Y+APEVL++K Y K D WS GV Y++L G Sbjct: 157 KIMISDFGLSKMEDPGSVLSTACGTPGYVAPEVLAQKPY-SKAVDCWSIGVIAYILLCGY 215 Query: 203 YPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKL 382 PF D D + F + + ++ P + +S + + + DP KR T + + Sbjct: 216 PPFYDENDAKLFEQILK--AEYEFDSPYWDDISDSAKDFIRHLMEKDPEKRFTCEQALQH 273 Query: 383 PWYL------KSLPKEIAERDRANF-KEPEKATETAASAAQPVEEI-MRIIQEGQ 523 PW K++ + ++E+ + NF K K A + + + ++ + QEGQ Sbjct: 274 PWIAGDTALDKNIHQSVSEQIKKNFAKSKWKQAFNATAVVRHMRKLQLGTSQEGQ 328
>KCC1A_MOUSE (Q91YS8) Calcium/calmodulin-dependent protein kinase type 1 (EC| 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha) Length = 374 Score = 80.1 bits (196), Expect = 3e-15 Identities = 52/175 (29%), Positives = 84/175 (48%), Gaps = 8/175 (4%) Frame = +2 Query: 23 RVKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGS 202 ++ I DFG SK S GTP Y+APEVL++K Y K D WS GV Y++L G Sbjct: 157 KIMISDFGLSKMEDPGSVLSTACGTPGYVAPEVLAQKPY-SKAVDCWSIGVIAYILLCGY 215 Query: 203 YPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKL 382 PF D D + F + + ++ P + +S + + + DP KR T + + Sbjct: 216 PPFYDENDAKLFEQILK--AEYEFDSPYWDDISDSAKDFIRHLMEKDPEKRFTCEQALQH 273 Query: 383 PWYL------KSLPKEIAERDRANF-KEPEKATETAASAAQPVEEI-MRIIQEGQ 523 PW K++ + ++E+ + NF K K A + + + ++ + QEGQ Sbjct: 274 PWIAGDTALDKNIHQSVSEQIKKNFAKSKWKQAFNATAVVRHMRKLQLGTSQEGQ 328
>TRIB1_MOUSE (Q8K4K4) Tribbles homolog 1 (TRB-1)| Length = 372 Score = 79.3 bits (194), Expect = 6e-15 Identities = 41/101 (40%), Positives = 60/101 (59%), Gaps = 1/101 (0%) Frame = +2 Query: 92 GTPAYIAPEVLSRK-EYDGKVADVWSCGVTLYVMLIGSYPFEDPEDPRNFRKTISRILGV 268 G PAY++PE+L+ Y GK ADVWS GV LY +L+G YPF D + F S+I Sbjct: 244 GCPAYVSPEILNTTGTYSGKAADVWSLGVMLYTLLVGRYPFHDSDPSALF----SKIRRG 299 Query: 269 QYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLPWY 391 Q+ IP++V + C L+ + +PS+R+T +I PW+ Sbjct: 300 QFCIPEHVSPKARC--LIRSLLRREPSERLTAPQILLHPWF 338
>PLO1_SCHPO (P50528) Serine/threonine-protein kinase plo1 (EC 2.7.11.21)| Length = 683 Score = 79.3 bits (194), Expect = 6e-15 Identities = 49/118 (41%), Positives = 68/118 (57%), Gaps = 2/118 (1%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTV-GTPAYIAPEVL-SRKEYDGKVADVWSCGVTLYVMLIG 199 VKI DFG + + + K T+ GTP YIAPE+L + KE D+WS GV +Y +LIG Sbjct: 177 VKIGDFGLAALLMDDEERKMTICGTPNYIAPEILFNSKEGHSFEVDLWSAGVVMYALLIG 236 Query: 200 SYPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEI 373 PF+D E +RK I YS P V +S++ + L+S + T DPS R +I +I Sbjct: 237 KPPFQDKEVKTIYRK----IKANSYSFPSNVDISAEAKDLISSLLTHDPSIRPSIDDI 290
>KCC1D_MOUSE (Q8BW96) Calcium/calmodulin-dependent protein kinase type 1D (EC| 2.7.11.17) (CaM kinase ID) (CaM kinase I delta) (CaMKI-delta) (CaM-KI delta) (CaMKI delta) (Camk1D) (CamKI-like protein kinase) (CKLiK) (mCKLiK) Length = 385 Score = 78.6 bits (192), Expect = 1e-14 Identities = 52/172 (30%), Positives = 80/172 (46%), Gaps = 6/172 (3%) Frame = +2 Query: 23 RVKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGS 202 ++ I DFG SK GTP Y+APEVL++K Y K D WS GV Y++L G Sbjct: 160 KIMISDFGLSKMEGKGDVMSTACGTPGYVAPEVLAQKPYS-KAVDCWSIGVIAYILLCGY 218 Query: 203 YPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKL 382 PF D D + F + + ++ P + +S + + + DP+KR T + + Sbjct: 219 PPFYDENDSKLFEQILK--AEYEFDSPYWDDISDSAKDFIRNLMEKDPNKRYTCEQAARH 276 Query: 383 PWYL------KSLPKEIAERDRANFKEPEKATETAASAAQPVEEIMRIIQEG 520 PW K++ + ++ + R NF K+ A A V MR +Q G Sbjct: 277 PWIAGDTALSKNIHESVSAQIRKNF---AKSKWRQAFNATAVVRHMRRLQLG 325
>MAPK3_MOUSE (Q3UMW7) MAP kinase-activated protein kinase 3 (EC 2.7.11.1)| (MAPK-activated protein kinase 3) (MAPKAP kinase 3) (MAPKAPK-3) Length = 384 Score = 78.6 bits (192), Expect = 1e-14 Identities = 45/128 (35%), Positives = 71/128 (55%), Gaps = 2/128 (1%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSY 205 +K+ DFG++K ++ P TP Y+APEVL ++YD K D+WS GV +Y++L G Sbjct: 185 LKLTDFGFAKETTQNALQTPCY-TPYYVAPEVLGPEKYD-KSCDMWSLGVIMYILLCGFP 242 Query: 206 PFEDPEDPRNFRKTISRILGVQYSIP--DYVRVSSDCRRLLSQIFTADPSKRITIAEIKK 379 PF RI QYS P +++ VS D ++L+ + DP++R+TI + Sbjct: 243 PFYSNTGQAISPGMKRRIRLGQYSFPNPEWLDVSEDAKQLIRLLLKTDPTERLTIMQFMN 302 Query: 380 LPWYLKSL 403 PW +S+ Sbjct: 303 HPWINQSM 310
>KCC2G_RAT (P11730) Calcium/calmodulin-dependent protein kinase type II gamma| chain (EC 2.7.11.17) (CaM-kinase II gamma chain) (CaM kinase II gamma subunit) (CaMK-II gamma subunit) Length = 527 Score = 78.6 bits (192), Expect = 1e-14 Identities = 41/122 (33%), Positives = 70/122 (57%), Gaps = 1/122 (0%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPK-PTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGS 202 VK+ DFG + + GTP Y++PEVL + Y GK D+W+CGV LY++L+G Sbjct: 153 VKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPY-GKPVDIWACGVILYILLVGY 211 Query: 203 YPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKL 382 PF D + + +++ + + P++ V+ + + L++Q+ T +P+KRIT + K Sbjct: 212 PPFWDEDQHKLYQQI--KAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITADQALKH 269 Query: 383 PW 388 PW Sbjct: 270 PW 271
>KCC2D_RAT (P15791) Calcium/calmodulin-dependent protein kinase type II delta| chain (EC 2.7.11.17) (CaM-kinase II delta chain) (CaM kinase II delta subunit) (CaMK-II delta subunit) Length = 533 Score = 78.6 bits (192), Expect = 1e-14 Identities = 37/99 (37%), Positives = 63/99 (63%) Frame = +2 Query: 92 GTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSYPFEDPEDPRNFRKTISRILGVQ 271 GTP Y++PEVL + Y GK D+W+CGV LY++L+G PF D + R +++ + Sbjct: 176 GTPGYLSPEVLRKDPY-GKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQI--KAGAYD 232 Query: 272 YSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLPW 388 + P++ V+ + + L++++ T +P+KRIT +E K PW Sbjct: 233 FPSPEWDTVTPEAKDLINKMLTINPAKRITASEALKHPW 271
>KCC2G_MOUSE (Q923T9) Calcium/calmodulin-dependent protein kinase type II gamma| chain (EC 2.7.11.17) (CaM-kinase II gamma chain) (CaM kinase II gamma subunit) (CaMK-II gamma subunit) Length = 529 Score = 78.6 bits (192), Expect = 1e-14 Identities = 41/122 (33%), Positives = 70/122 (57%), Gaps = 1/122 (0%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPK-PTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGS 202 VK+ DFG + + GTP Y++PEVL + Y GK D+W+CGV LY++L+G Sbjct: 153 VKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPY-GKPVDIWACGVILYILLVGY 211 Query: 203 YPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKL 382 PF D + + +++ + + P++ V+ + + L++Q+ T +P+KRIT + K Sbjct: 212 PPFWDEDQHKLYQQI--KAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITADQALKH 269 Query: 383 PW 388 PW Sbjct: 270 PW 271
>KCC2D_HUMAN (Q13557) Calcium/calmodulin-dependent protein kinase type II delta| chain (EC 2.7.11.17) (CaM-kinase II delta chain) (CaM kinase II delta subunit) (CaMK-II delta subunit) Length = 499 Score = 78.6 bits (192), Expect = 1e-14 Identities = 37/99 (37%), Positives = 63/99 (63%) Frame = +2 Query: 92 GTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSYPFEDPEDPRNFRKTISRILGVQ 271 GTP Y++PEVL + Y GK D+W+CGV LY++L+G PF D + R +++ + Sbjct: 176 GTPGYLSPEVLRKDPY-GKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQI--KAGAYD 232 Query: 272 YSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLPW 388 + P++ V+ + + L++++ T +P+KRIT +E K PW Sbjct: 233 FPSPEWDTVTPEAKDLINKMLTINPAKRITASEALKHPW 271
>KCC2G_HUMAN (Q13555) Calcium/calmodulin-dependent protein kinase type II gamma| chain (EC 2.7.11.17) (CaM-kinase II gamma chain) (CaM kinase II gamma subunit) (CaMK-II gamma subunit) Length = 558 Score = 78.6 bits (192), Expect = 1e-14 Identities = 41/122 (33%), Positives = 70/122 (57%), Gaps = 1/122 (0%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPK-PTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGS 202 VK+ DFG + + GTP Y++PEVL + Y GK D+W+CGV LY++L+G Sbjct: 153 VKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPY-GKPVDIWACGVILYILLVGY 211 Query: 203 YPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKL 382 PF D + + +++ + + P++ V+ + + L++Q+ T +P+KRIT + K Sbjct: 212 PPFWDEDQHKLYQQI--KAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITADQALKH 269 Query: 383 PW 388 PW Sbjct: 270 PW 271
>KPCD3_MOUSE (Q8K1Y2) Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein| kinase C nu type) (nPKC-nu) Length = 889 Score = 77.8 bits (190), Expect = 2e-14 Identities = 43/125 (34%), Positives = 69/125 (55%) Frame = +2 Query: 14 PTPRVKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVML 193 P P+VK+CDFG+++ S + VGTPAY+APEVL K Y+ + D+WS GV +YV L Sbjct: 711 PFPQVKLCDFGFARIIGEKSFRRSVVGTPAYLAPEVLRSKGYN-RSLDMWSVGVIVYVSL 769 Query: 194 IGSYPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEI 373 G++PF + ED + + + Y + +SS+ L++ + KR ++ + Sbjct: 770 SGTFPFNEDEDINDQIQNAA----FMYPPNPWREISSEAIDLINNLLQVKMRKRYSVDKS 825 Query: 374 KKLPW 388 PW Sbjct: 826 LSHPW 830
>TSSK3_HUMAN (Q96PN8) Testis-specific serine/threonine-protein kinase 3 (EC| 2.7.11.1) (TSSK-3) (Testis-specific kinase 3) (TSK-3) (Serine/threonine-protein kinase 22C) Length = 268 Score = 77.8 bits (190), Expect = 2e-14 Identities = 46/123 (37%), Positives = 67/123 (54%), Gaps = 2/123 (1%) Frame = +2 Query: 26 VKICDFGYSKSA-LLHSKPKPTV-GTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIG 199 +K+ DFG++K H + T G+ AY APEVL +D K DVWS GV LYVML Sbjct: 147 LKLTDFGFAKVLPKSHRELSQTFCGSTAYAAPEVLQGIPHDSKKGDVWSMGVVLYVMLCA 206 Query: 200 SYPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKK 379 S PF+D + P+ + + S P ++ +S+DC+ LL ++ D R +I E+ Sbjct: 207 SLPFDDTDIPKMLWQQQKGV-----SFPTHLSISADCQDLLKRLLEPDMILRPSIEEVSW 261 Query: 380 LPW 388 PW Sbjct: 262 HPW 264
>KPCD1_HUMAN (Q15139) Serine/threonine-protein kinase D1 (EC 2.7.11.13) (nPKC-D1)| (Protein kinase D) (Protein kinase C mu type) (nPKC-mu) Length = 912 Score = 77.8 bits (190), Expect = 2e-14 Identities = 47/145 (32%), Positives = 75/145 (51%), Gaps = 8/145 (5%) Frame = +2 Query: 14 PTPRVKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVML 193 P P+VK+CDFG+++ S + VGTPAY+APEVL K Y+ + D+WS GV +YV L Sbjct: 719 PFPQVKLCDFGFARIIGEKSFRRSVVGTPAYLAPEVLRNKGYN-RSLDMWSVGVIIYVSL 777 Query: 194 IGSYPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEI 373 G++PF + ED + + + Y + +S + L++ + KR ++ + Sbjct: 778 SGTFPFNEDEDIHDQIQNAA----FMYPPNPWKEISHEAIDLINNLLQVKMRKRYSVDKT 833 Query: 374 KKLPWY--------LKSLPKEIAER 424 PW L+ L +I ER Sbjct: 834 LSHPWLQDYQTWLDLRELECKIGER 858
>ICL1_KLULA (Q6CWQ4) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 361 Score = 77.8 bits (190), Expect = 2e-14 Identities = 45/121 (37%), Positives = 67/121 (55%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSY 205 +K+ DFG+S K K GT Y++PE++ +EY+ KV DVW+ GV Y +L+GS Sbjct: 237 IKLTDFGWSVYNEDGQKRKTLCGTIDYLSPELIKSREYNNKV-DVWALGVLTYELLVGSP 295 Query: 206 PFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLP 385 PFE+ +R RIL P + VS R L+ ++ +PSKRI ++E+K Sbjct: 296 PFEEDTKEMTYR----RILRCDLKFP--LNVSPQARDLIVRLLQFEPSKRIPLSEVKSHA 349 Query: 386 W 388 W Sbjct: 350 W 350
>KCC1D_HUMAN (Q8IU85) Calcium/calmodulin-dependent protein kinase type 1D (EC| 2.7.11.17) (CaM kinase ID) (CaM kinase I delta) (CaMKI-delta) (CaM-KI delta) (CaMKI delta) (Camk1D) (CamKI-like protein kinase) (CKLiK) Length = 385 Score = 77.4 bits (189), Expect = 2e-14 Identities = 44/145 (30%), Positives = 70/145 (48%), Gaps = 6/145 (4%) Frame = +2 Query: 23 RVKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGS 202 ++ I DFG SK GTP Y+APEVL++K Y K D WS GV Y++L G Sbjct: 160 KIMISDFGLSKMEGKGDVMSTACGTPGYVAPEVLAQKPYS-KAVDCWSIGVIAYILLCGY 218 Query: 203 YPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKL 382 PF D D + F + + ++ P + +S + + + DP+KR T + + Sbjct: 219 PPFYDENDSKLFEQILK--AEYEFDSPYWDDISDSAKDFIRNLMEKDPNKRYTCEQAARH 276 Query: 383 PWYL------KSLPKEIAERDRANF 439 PW K++ + ++ + R NF Sbjct: 277 PWIAGDTALNKNIHESVSAQIRKNF 301
>MAPK3_BOVIN (Q3SYZ2) MAP kinase-activated protein kinase 3 (EC 2.7.11.1)| (MAPK-activated protein kinase 3) (MAPKAP kinase 3) (MAPKAPK-3) Length = 384 Score = 77.4 bits (189), Expect = 2e-14 Identities = 52/166 (31%), Positives = 83/166 (50%), Gaps = 10/166 (6%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSY 205 +K+ DFG++K ++ P TP Y+APEVL ++YD K D+WS GV +Y++L G Sbjct: 185 LKLTDFGFAKETTQNALQTPCY-TPYYVAPEVLGPEKYD-KSCDMWSLGVIMYILLCGFP 242 Query: 206 PFEDPEDPRNFRKTISRILGVQYSIP--DYVRVSSDCRRLLSQIFTADPSKRITIAEIKK 379 PF RI QY P ++ VS D ++L+ + DP++R+TI + Sbjct: 243 PFYSNTGQAISPGMKRRIRLGQYGFPSPEWSEVSEDAKQLIRLLLKTDPTERLTITQFMN 302 Query: 380 LPWYLKSL--------PKEIAERDRANFKEPEKATETAASAAQPVE 493 PW +S+ + + DR ++ E K T+A A V+ Sbjct: 303 HPWINQSMVVPQTPLHTARVLQEDRDHWDE-VKEEMTSALATMRVD 347
>KPCD1_MOUSE (Q62101) Serine/threonine-protein kinase D1 (EC 2.7.11.13) (nPKC-D1)| (Protein kinase D) (Protein kinase C mu type) (nPKC-mu) Length = 918 Score = 77.4 bits (189), Expect = 2e-14 Identities = 42/125 (33%), Positives = 68/125 (54%) Frame = +2 Query: 14 PTPRVKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVML 193 P P+VK+CDFG+++ S + VGTPAY+APEVL K Y+ + D+WS GV +YV L Sbjct: 725 PFPQVKLCDFGFARIIGEKSFRRSVVGTPAYLAPEVLRNKGYN-RSLDMWSVGVIIYVSL 783 Query: 194 IGSYPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEI 373 G++PF + ED + + + Y + +S + L++ + KR ++ + Sbjct: 784 SGTFPFNEDEDIHDQIQNAA----FMYPPNPWKEISHEAIDLINNLLQVKMRKRYSVDKT 839 Query: 374 KKLPW 388 PW Sbjct: 840 LSHPW 844
>TSSK2_HUMAN (Q96PF2) Testis-specific serine/threonine-protein kinase 2 (EC| 2.7.11.1) (TSSK-2) (Testis-specific kinase 2) (TSK-2) (Serine/threonine-protein kinase 22B) (DiGeorge syndrome protein G) Length = 358 Score = 77.0 bits (188), Expect = 3e-14 Identities = 49/144 (34%), Positives = 72/144 (50%), Gaps = 5/144 (3%) Frame = +2 Query: 26 VKICDFGYSKSALLHSK-----PKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVM 190 +K+ DFG+SK L S K G+ AY APEVL Y KV D+WS GV LY+M Sbjct: 150 IKLSDFGFSKRCLRDSNGRIILSKTFCGSAAYAAPEVLQSIPYQPKVYDIWSLGVILYIM 209 Query: 191 LIGSYPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAE 370 + GS P++D + RK + + P ++ +C+ L+ ++ D S+R+ I E Sbjct: 210 VCGSMPYDDSD----IRKMLRIQKEHRVDFPRSKNLTCECKDLIYRMLQPDVSQRLHIDE 265 Query: 371 IKKLPWYLKSLPKEIAERDRANFK 442 I W PK + A+FK Sbjct: 266 ILSHSWLQPPKPKATSS---ASFK 286
>MAPK3_HUMAN (Q16644) MAP kinase-activated protein kinase 3 (EC 2.7.11.1)| (MAPK-activated protein kinase 3) (MAPKAP kinase 3) (MAPKAPK-3) (Chromosome 3p kinase) (3pK) Length = 382 Score = 77.0 bits (188), Expect = 3e-14 Identities = 44/128 (34%), Positives = 69/128 (53%), Gaps = 2/128 (1%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSY 205 +K+ DFG++K ++ P TP Y+APEVL ++YD K D+WS GV +Y++L G Sbjct: 183 LKLTDFGFAKETTQNALQTPCY-TPYYVAPEVLGPEKYD-KSCDMWSLGVIMYILLCGFP 240 Query: 206 PFEDPEDPRNFRKTISRILGVQYSIP--DYVRVSSDCRRLLSQIFTADPSKRITIAEIKK 379 PF RI QY P ++ VS D ++L+ + DP++R+TI + Sbjct: 241 PFYSNTGQAISPGMKRRIRLGQYGFPNPEWSEVSEDAKQLIRLLLKTDPTERLTITQFMN 300 Query: 380 LPWYLKSL 403 PW +S+ Sbjct: 301 HPWINQSM 308
>MELK_MOUSE (Q61846) Maternal embryonic leucine zipper kinase (EC 2.7.11.1)| (Protein kinase PK38) (mPK38) Length = 643 Score = 77.0 bits (188), Expect = 3e-14 Identities = 54/173 (31%), Positives = 86/173 (49%), Gaps = 13/173 (7%) Frame = +2 Query: 23 RVKICDFGYSKSALLHSKPKPT--------VGTPAYIAPEVLSRKEYDGKVADVWSCGVT 178 ++K+ DFG L +KPK G+ AY APE++ K Y G ADVWS G+ Sbjct: 145 KLKLIDFG------LCAKPKGNKDYHLQTCCGSLAYAAPELIQGKSYLGSEADVWSMGIL 198 Query: 179 LYVMLIGSYPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRI 358 LYV++ G PF+D N +I+ +Y +P ++ SS LL Q+ DP KRI Sbjct: 199 LYVLMCGFLPFDDD----NVMALYKKIMRGKYEVPKWLSPSSIL--LLQQMLQVDPKKRI 252 Query: 359 TIAEIKKLPWYLK--SLPKEIAERDRANFKEPEKATETAA---SAAQPVEEIM 502 ++ + PW ++ S P E + + + TE + S+ Q +E+++ Sbjct: 253 SMRNLLNHPWVMQDYSCPVEWQSKTPLTHLDEDCVTELSVHHRSSRQTMEDLI 305
>CHK1_RAT (Q91ZN7) Serine/threonine-protein kinase Chk1 (EC 2.7.11.1)| Length = 476 Score = 76.6 bits (187), Expect = 4e-14 Identities = 50/139 (35%), Positives = 74/139 (53%), Gaps = 3/139 (2%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPK---PTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLI 196 +KI DFG + +++ + GT Y+APE+L RKE+ + DVWSCG+ L ML Sbjct: 144 LKISDFGLATVFRHNNRERLLNKMCGTLPYVAPELLKRKEFHAEPVDVWSCGIVLTAMLA 203 Query: 197 GSYPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIK 376 G P++ P D + S + + + ++ S LL +I +PS RITI +IK Sbjct: 204 GELPWDQPSDS---CQEYSDWKEKKTYLNPWKKIDSAPLALLHKILVENPSARITIPDIK 260 Query: 377 KLPWYLKSLPKEIAERDRA 433 K WY K L + A+R RA Sbjct: 261 KDRWYNKPLNRG-AKRPRA 278
>MAPK3_RAT (Q66H84) MAP kinase-activated protein kinase 3 (EC 2.7.11.1)| (MAPK-activated protein kinase 3) (MAPKAP kinase 3) (MAPKAPK-3) Length = 384 Score = 76.6 bits (187), Expect = 4e-14 Identities = 44/128 (34%), Positives = 69/128 (53%), Gaps = 2/128 (1%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSY 205 +K+ DFG++K ++ P TP Y+APEVL ++YD K D+WS GV +Y++L G Sbjct: 185 LKLTDFGFAKETTQNALQTPCY-TPYYVAPEVLGPEKYD-KSCDMWSLGVIMYILLCGFP 242 Query: 206 PFEDPEDPRNFRKTISRILGVQYSIP--DYVRVSSDCRRLLSQIFTADPSKRITIAEIKK 379 PF RI QY P ++ VS D ++L+ + DP++R+TI + Sbjct: 243 PFYSNTGQAISPGMKRRIRLGQYGFPKPEWADVSEDAKQLIRLLLKTDPTERLTIMQFMN 302 Query: 380 LPWYLKSL 403 PW +S+ Sbjct: 303 HPWINQSM 310
>KPCD3_HUMAN (O94806) Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein| kinase C nu type) (nPKC-nu) (Protein kinase EPK2) Length = 890 Score = 76.6 bits (187), Expect = 4e-14 Identities = 42/125 (33%), Positives = 68/125 (54%) Frame = +2 Query: 14 PTPRVKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVML 193 P P+VK+CDFG+++ S + VGTPAY+APEVL K Y+ + D+WS GV +YV L Sbjct: 712 PFPQVKLCDFGFARIIGEKSFRRSVVGTPAYLAPEVLRSKGYN-RSLDMWSVGVIIYVSL 770 Query: 194 IGSYPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEI 373 G++PF + ED + + + Y + +S + L++ + KR ++ + Sbjct: 771 SGTFPFNEDEDINDQIQNAA----FMYPPNPWREISGEAIDLINNLLQVKMRKRYSVDKS 826 Query: 374 KKLPW 388 PW Sbjct: 827 LSHPW 831
>SSP1_SCHPO (P50526) Serine/threonine-protein kinase ssp1 (EC 2.7.11.1)| Length = 652 Score = 76.6 bits (187), Expect = 4e-14 Identities = 60/174 (34%), Positives = 86/174 (49%), Gaps = 14/174 (8%) Frame = +2 Query: 26 VKICDFG--YSKSALLHS----KPKPTVGTPAYIAPEV----LSR-KEYDGKVADVWSCG 172 VKI DFG Y +A L+ + TVGTPA+ APE+ L R + + DVW+ G Sbjct: 281 VKISDFGVSYIANAGLNEDNDVELAKTVGTPAFFAPELCWTDLDRPRPKISEAIDVWALG 340 Query: 173 VTLYVMLIGSYPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSK 352 VTL+ +L G PF + F K ++ L + S PD + + R LL ++ DP + Sbjct: 341 VTLFCLLFGRCPFNASMEYELFDKIVNERLNIP-STPD---IGEEGRDLLKRLLCKDPEQ 396 Query: 353 RITIAEIKKLPWYLKSL---PKEIAERDRANFKEPEKATETAASAAQPVEEIMR 505 RIT+ E+K PW L L K + D + E +T+ ASA V + R Sbjct: 397 RITLVEVKLHPWTLDGLKDPEKWLQNTDPSTVSRVEVSTDEVASAISLVGRLRR 450
>CHK1_HUMAN (O14757) Serine/threonine-protein kinase Chk1 (EC 2.7.11.1)| Length = 476 Score = 76.3 bits (186), Expect = 5e-14 Identities = 46/131 (35%), Positives = 69/131 (52%), Gaps = 3/131 (2%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPK---PTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLI 196 +KI DFG + +++ + GT Y+APE+L R+E+ + DVWSCG+ L ML Sbjct: 144 LKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLKRREFHAEPVDVWSCGIVLTAMLA 203 Query: 197 GSYPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIK 376 G P++ P D + S + + + ++ S LL +I +PS RITI +IK Sbjct: 204 GELPWDQPSDS---CQEYSDWKEKKTYLNPWKKIDSAPLALLHKILVENPSARITIPDIK 260 Query: 377 KLPWYLKSLPK 409 K WY K L K Sbjct: 261 KDRWYNKPLKK 271
>YP141_YEAST (Q03002) Putative serine/threonine-protein kinase YPL141C (EC| 2.7.11.1) Length = 865 Score = 75.9 bits (185), Expect = 6e-14 Identities = 45/124 (36%), Positives = 68/124 (54%), Gaps = 5/124 (4%) Frame = +2 Query: 32 ICDFGYSKSALLHSK-PKPTVGTPAYIAPE-VLSRKEYDGKVADVWSCGVTLYVMLIGSY 205 I DFG+ ++ K + G+P Y APE V+S + Y+ + AD+WSCGV LY +L G Sbjct: 191 ITDFGFVNEFCSRNELMKTSCGSPCYAAPELVISAEPYEARKADIWSCGVILYAILAGYL 250 Query: 206 PF-EDPEDPR--NFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIK 376 P+ +DP +P + + + I PDY+ R LL ++ +DP KRI + +IK Sbjct: 251 PWDDDPNNPEGSDIGRLYNYINSTPLKFPDYILPIP--RDLLRRMLVSDPKKRINLKQIK 308 Query: 377 KLPW 388 K W Sbjct: 309 KHEW 312
>KPSH1_BRARE (Q501V0) Serine/threonine-protein kinase H1 homolog (EC 2.7.11.1)| Length = 422 Score = 75.9 bits (185), Expect = 6e-14 Identities = 55/180 (30%), Positives = 94/180 (52%), Gaps = 15/180 (8%) Frame = +2 Query: 23 RVKICDFGYSKSALLHSK--PKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLI 196 ++ I DFG + + + K T GTP YIAPE+L RK Y V D+W+ GV Y++L Sbjct: 232 KIMITDFGLASTRKKGDECLMKTTCGTPEYIAPEILVRKPYTNAV-DMWALGVISYILLS 290 Query: 197 GSYPFEDPEDPRNFRKTISRILGVQYSI--PDYVRVSSDCRRLLSQIFTADPSKRITIAE 370 G+ PFED R +R +IL +YS + VS+ + + ++ T DP++R++ + Sbjct: 291 GTMPFEDDNRMRLYR----QILKGKYSFSGEPWPSVSNLAKDFIDRVLTVDPNERLSAGQ 346 Query: 371 IKKLPWY--------LKSLPKEIAER--DRANFK-EPEKATETAASAAQPVEEIMRIIQE 517 K PW +K+L + I++ RA+ + K++++A S+ R ++E Sbjct: 347 ALKHPWIVSMAASSSMKNLHRSISQNLLKRASSRCHSTKSSQSARSSRSTKSSKARRLRE 406
>CHK1_MOUSE (O35280) Serine/threonine-protein kinase Chk1 (EC 2.7.11.1)| Length = 476 Score = 75.9 bits (185), Expect = 6e-14 Identities = 50/139 (35%), Positives = 73/139 (52%), Gaps = 3/139 (2%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPK---PTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLI 196 +KI DFG + +++ + GT Y+APE+L RKE+ + DVWSCG+ L ML Sbjct: 144 LKISDFGLATVFRHNNRERLLNKMCGTLPYVAPELLKRKEFHAEPVDVWSCGIVLTAMLA 203 Query: 197 GSYPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIK 376 G P++ P D + S + + + ++ S LL +I PS RITI +IK Sbjct: 204 GELPWDQPSDS---CQEYSDWKEKKTYLNPWKKIDSAPLALLHKILVETPSARITIPDIK 260 Query: 377 KLPWYLKSLPKEIAERDRA 433 K WY K L + A+R RA Sbjct: 261 KDRWYNKPLNRG-AKRPRA 278
>TSSK6_MOUSE (Q925K9) Testis-specific serine/threonine-protein kinase 6 (EC| 2.7.11.1) (TSSK-6) (Small serine/threonine kinase) (Serine/threonine-protein kinase SSTK) Length = 273 Score = 75.9 bits (185), Expect = 6e-14 Identities = 48/128 (37%), Positives = 69/128 (53%), Gaps = 6/128 (4%) Frame = +2 Query: 23 RVKICDFGYSKSALLHSKPKPTV---GTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVML 193 RVKI DFG+ + A H P + G+ AY +PEVL YD K DVWS GV LYVM+ Sbjct: 149 RVKITDFGFGRQA--HGYPDLSTTYCGSAAYASPEVLLGIPYDPKKYDVWSLGVVLYVMV 206 Query: 194 IGSYPFEDPED---PRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITI 364 G PF+D + PR ++ GV Y PD + +S C+ L++++ PS R + Sbjct: 207 TGCMPFDDSDIAGLPRRQKR------GVLY--PDGLELSERCKSLIAELLQFSPSARPSA 258 Query: 365 AEIKKLPW 388 ++ + W Sbjct: 259 GQVARNGW 266
>KPCD2_HUMAN (Q9BZL6) Serine/threonine-protein kinase D2 (EC 2.7.11.13) (nPKC-D2)| Length = 878 Score = 75.9 bits (185), Expect = 6e-14 Identities = 41/125 (32%), Positives = 68/125 (54%) Frame = +2 Query: 14 PTPRVKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVML 193 P P+VK+CDFG+++ S + VGTPAY+APEVL + Y+ + D+WS GV +YV L Sbjct: 687 PFPQVKLCDFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQGYN-RSLDMWSVGVIMYVSL 745 Query: 194 IGSYPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEI 373 G++PF + ED + + + Y + +S+ L++ + KR ++ + Sbjct: 746 SGTFPFNEDEDINDQIQNAA----FMYPASPWSHISAGAIDLINNLLQVKMRKRYSVDKS 801 Query: 374 KKLPW 388 PW Sbjct: 802 LSHPW 806
>TSSK3_MOUSE (Q9D2E1) Testis-specific serine/threonine-protein kinase 3 (EC| 2.7.11.1) (TSSK-3) (Testis-specific kinase 3) (TSK-3) (Serine/threonine-protein kinase 22C) Length = 268 Score = 75.5 bits (184), Expect = 8e-14 Identities = 45/124 (36%), Positives = 69/124 (55%), Gaps = 3/124 (2%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPT---VGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLI 196 +K+ DFG++K L S+ + + G+ AY APEVL +D K DVWS GV LYVML Sbjct: 147 LKLTDFGFAK-VLPKSRRELSQTFCGSTAYAAPEVLQGIPHDSKKGDVWSMGVVLYVMLC 205 Query: 197 GSYPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIK 376 S PF+D + P+ + + S P ++ +S++C+ LL ++ D R +I E+ Sbjct: 206 ASLPFDDTDIPKMLWQQQKGV-----SFPTHLGISTECQDLLKRLLEPDMILRPSIEEVS 260 Query: 377 KLPW 388 PW Sbjct: 261 WHPW 264
>CDPK1_PLAFK (P62343) Calcium-dependent protein kinase 1 (EC 2.7.11.1) (PfCPK)| (PfCDPK1) Length = 523 Score = 75.5 bits (184), Expect = 8e-14 Identities = 47/124 (37%), Positives = 64/124 (51%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSY 205 +KI DFG S +K + +GT YIAPEVL RK+Y+ K DVWSCGV LY++L G Sbjct: 207 IKIVDFGLSSFFSKDNKLRDRLGTAYYIAPEVL-RKKYNEK-CDVWSCGVILYILLCGYP 264 Query: 206 PFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLP 385 PF D +K + D+ +S + + L+ + T D +KRIT E Sbjct: 265 PFGGQNDQDIIKKVEKG--KYYFDFNDWKNISEEAKELIKLMLTYDYNKRITAKEALNSK 322 Query: 386 WYLK 397 W K Sbjct: 323 WIKK 326
>CDPK1_PLAF7 (P62344) Calcium-dependent protein kinase 1 (EC 2.7.11.1)| Length = 523 Score = 75.5 bits (184), Expect = 8e-14 Identities = 47/124 (37%), Positives = 64/124 (51%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSY 205 +KI DFG S +K + +GT YIAPEVL RK+Y+ K DVWSCGV LY++L G Sbjct: 207 IKIVDFGLSSFFSKDNKLRDRLGTAYYIAPEVL-RKKYNEK-CDVWSCGVILYILLCGYP 264 Query: 206 PFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLP 385 PF D +K + D+ +S + + L+ + T D +KRIT E Sbjct: 265 PFGGQNDQDIIKKVEKG--KYYFDFNDWKNISEEAKELIKLMLTYDYNKRITAKEALNSK 322 Query: 386 WYLK 397 W K Sbjct: 323 WIKK 326
>KS6AA_CHICK (P18652) Ribosomal protein S6 kinase 2 alpha (EC 2.7.11.1) (Ribosomal| protein S6 kinase II alpha) (S6KII-alpha) (P90-RSK) (MAP kinase-activated protein kinase 1) (MAPK-activated protein kinase 1) (MAPKAP kinase 1) (MAPKAPK-1) Length = 752 Score = 75.5 bits (184), Expect = 8e-14 Identities = 56/177 (31%), Positives = 98/177 (55%), Gaps = 8/177 (4%) Frame = +2 Query: 2 LDGSPTPR-VKICDFGYSKSALLHSKPKPT-VGTPAYIAPEVLSRKEYDGKVADVWSCGV 175 +D S P ++ICDFG++K + T T ++APEVL R+ YD + D+WS GV Sbjct: 561 VDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYD-EGCDIWSLGV 619 Query: 176 TLYVMLIGSYPFED-PEDPRNFRKTISRILGVQYSI--PDYVRVSSDCRRLLSQIFTADP 346 LY ML G PF + P D + ++RI G ++S+ ++ +S + L+S++ DP Sbjct: 620 LLYTMLAGCTPFANGPSDTP--EEILTRIGGGKFSVNGGNWDTISDVAKDLVSKMLHVDP 677 Query: 347 SKRITIAEIKKLPWYLK--SLPK-EIAERDRANFKEPEKATETAASAAQPVEEIMRI 508 +R+T ++ + PW + SLP+ ++ +D K AT +A ++++P ++ I Sbjct: 678 HQRLTAKQVLQHPWITQKDSLPQSQLNYQDVQLVKGAMAATYSALNSSKPSPQLKPI 734 Score = 68.9 bits (167), Expect = 8e-12 Identities = 44/128 (34%), Positives = 75/128 (58%), Gaps = 6/128 (4%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTV-GTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGS 202 +K+ DFG SK A+ H K + GT Y+APEV++R+ + AD WS GV ++ ML GS Sbjct: 219 IKLTDFGLSKEAIDHEKKAYSFCGTVEYMAPEVVNRQGHSHS-ADWWSYGVLMFEMLTGS 277 Query: 203 YPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRI-----TIA 367 PF+ ++ ++T++ IL + +P + +S++ + LL +F +P+ R+ Sbjct: 278 LPFQG----KDRKETMTLILKAKLGMPQF--LSAEAQSLLRALFKRNPANRLGSGPDGAE 331 Query: 368 EIKKLPWY 391 EIK+ P+Y Sbjct: 332 EIKRHPFY 339
>IPL1_DEBHA (Q6BVA0) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 412 Score = 75.5 bits (184), Expect = 8e-14 Identities = 44/127 (34%), Positives = 67/127 (52%), Gaps = 2/127 (1%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTV--GTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIG 199 +K+ DFG+S +L S K GT Y+ PE++ E+D V D+WS G+ Y L+G Sbjct: 285 IKLSDFGWSVKSLPSSSTKRLTICGTLDYLPPEMIESNEHDYTV-DIWSLGILCYEFLVG 343 Query: 200 SYPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKK 379 PFE+ + T RI V IP ++ SS+ L+ ++ P KRIT+AE+ Sbjct: 344 KPPFEEIDK----NSTYKRIAKVDLKIPSFL--SSEATDLILRLLQKSPKKRITLAEVMN 397 Query: 380 LPWYLKS 400 PW + + Sbjct: 398 HPWIMNN 404
>KPSH1_HUMAN (P11801) Serine/threonine-protein kinase H1 (EC 2.7.11.1) (PSK-H1)| Length = 423 Score = 75.1 bits (183), Expect = 1e-13 Identities = 50/176 (28%), Positives = 84/176 (47%), Gaps = 14/176 (7%) Frame = +2 Query: 23 RVKICDFGYSKSALLHSK--PKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLI 196 ++ I DFG + + K T GTP YIAPEVL RK Y V D+W+ GV Y++L Sbjct: 233 KIIITDFGLASARKKGDDCLMKTTCGTPEYIAPEVLVRKPYTNSV-DMWALGVIAYILLS 291 Query: 197 GSYPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIK 376 G+ PFED R +R+ + YS + VS+ + + ++ T DP R+T + Sbjct: 292 GTMPFEDDNRTRLYRQILRG--KYSYSGEPWPSVSNLAKDFIDRLLTVDPGARMTALQAL 349 Query: 377 KLPWYL------------KSLPKEIAERDRANFKEPEKATETAASAAQPVEEIMRI 508 + PW + +S+ + + +R + + + A T +S + + R+ Sbjct: 350 RHPWVVSMAASSSMKNLHRSISQNLLKRASSRCQSTKSAQSTRSSRSTRSNKSRRV 405
>KS6A1_RAT (Q63531) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1) (S6K-alpha| 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 735 Score = 75.1 bits (183), Expect = 1e-13 Identities = 55/177 (31%), Positives = 97/177 (54%), Gaps = 8/177 (4%) Frame = +2 Query: 2 LDGSPTPR-VKICDFGYSKSALLHSKPKPT-VGTPAYIAPEVLSRKEYDGKVADVWSCGV 175 +D S P ++ICDFG++K + T T ++APEVL R+ YD + D+WS GV Sbjct: 544 VDESGNPECLRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYD-EGCDIWSLGV 602 Query: 176 TLYVMLIGSYPFED-PEDPRNFRKTISRILGVQYSIP--DYVRVSSDCRRLLSQIFTADP 346 LY ML G PF + P D + ++RI ++++ ++ VS + L+S++ DP Sbjct: 603 LLYTMLAGYTPFANGPSDTP--EEILTRISSGKFTLSGGNWNTVSETAKDLVSKMLHVDP 660 Query: 347 SKRITIAEIKKLPWYLK--SLPK-EIAERDRANFKEPEKATETAASAAQPVEEIMRI 508 +R+T ++ + PW + LP+ +++ +D K AT +A S+++P ++ I Sbjct: 661 HQRLTAKQVLQHPWITQKDKLPQSQLSHQDLQLVKGGMAATYSALSSSKPTPQLKPI 717 Score = 65.5 bits (158), Expect = 9e-11 Identities = 39/112 (34%), Positives = 68/112 (60%), Gaps = 1/112 (0%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTV-GTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGS 202 +K+ DFG SK A+ H K + GT Y+APEV++R+ + AD WS GV ++ ML GS Sbjct: 201 IKLTDFGLSKEAIDHEKKAYSFCGTVEYMAPEVVNRQGHTHS-ADWWSYGVLMFEMLTGS 259 Query: 203 YPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRI 358 PF+ ++ ++T++ IL + +P + +S++ + LL +F +P+ R+ Sbjct: 260 LPFQG----KDRKETMTLILKAKLGMPQF--LSTEAQSLLRALFKRNPANRL 305
>STK6_MOUSE (P97477) Serine/threonine-protein kinase 6 (EC 2.7.11.1)| (Aurora-family kinase 1) (Aurora/IPL1-related kinase 1) (Ipl1- and aurora-related kinase 1) (Aurora-A) (Serine/threonine-protein kinase Ayk1) Length = 395 Score = 74.7 bits (182), Expect = 1e-13 Identities = 44/121 (36%), Positives = 71/121 (58%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSY 205 +KI DFG+S A S+ GT Y+ PE++ + +D KV D+WS GV Y L+G Sbjct: 261 LKIADFGWSVHAP-SSRRTTMCGTLDYLPPEMIEGRMHDEKV-DLWSLGVLCYEFLVGMP 318 Query: 206 PFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLP 385 PFE +++T RI V+++ PD+V + R L+S++ + S+R+T+AE+ + P Sbjct: 319 PFE----AHTYQETYRRISRVEFTFPDFV--TEGARDLISRLLKHNASQRLTLAEVLEHP 372 Query: 386 W 388 W Sbjct: 373 W 373
>YP150_YEAST (Q12152) Putative serine/threonine-protein kinase YPL150W (EC| 2.7.11.1) Length = 901 Score = 74.7 bits (182), Expect = 1e-13 Identities = 34/120 (28%), Positives = 68/120 (56%) Frame = +2 Query: 29 KICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSYP 208 K+ DFG+++ + + + GT Y+APE++ R+ YDG D+WS GV LY ++ G P Sbjct: 172 KLTDFGFTRECMTKTTLETVCGTTVYMAPELIERRTYDGFKIDIWSLGVILYTLITGYLP 231 Query: 209 FEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLPW 388 F+D ++ + K ++ + D + D R L+S++ +P +R +++++ + P+ Sbjct: 232 FDDDDEAKTKWKIVN-----EEPKYDAKVIPDDARDLISRLLAKNPGERPSLSQVLRHPF 286
>MELK_HUMAN (Q14680) Maternal embryonic leucine zipper kinase (EC 2.7.11.1)| (hMELK) (Protein kinase PK38) (hPK38) Length = 651 Score = 74.7 bits (182), Expect = 1e-13 Identities = 46/133 (34%), Positives = 69/133 (51%), Gaps = 8/133 (6%) Frame = +2 Query: 23 RVKICDFGYSKSALLHSKPKPT--------VGTPAYIAPEVLSRKEYDGKVADVWSCGVT 178 ++K+ DFG L +KPK G+ AY APE++ K Y G ADVWS G+ Sbjct: 145 KLKLIDFG------LCAKPKGNKDYHLQTCCGSLAYAAPELIQGKSYLGSEADVWSMGIL 198 Query: 179 LYVMLIGSYPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRI 358 LYV++ G PF+D N +I+ +Y +P ++ SS LL Q+ DP KRI Sbjct: 199 LYVLMCGFLPFDDD----NVMALYKKIMRGKYDVPKWLSPSSIL--LLQQMLQVDPKKRI 252 Query: 359 TIAEIKKLPWYLK 397 ++ + PW ++ Sbjct: 253 SMKNLLNHPWIMQ 265
>CDR2_SCHPO (P87050) Mitosis inducer protein kinase cdr2 (EC 2.7.11.1)| Length = 775 Score = 74.3 bits (181), Expect = 2e-13 Identities = 36/121 (29%), Positives = 66/121 (54%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSY 205 +KI +FG + + + G+P Y +PE++ + YDG +D+WSCG+ + +L G Sbjct: 147 IKIGEFGMASIQQPGKLLQTSCGSPHYASPEIIMGRSYDGCASDIWSCGIIFFALLTGKL 206 Query: 206 PFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLP 385 PF+D N R + ++ Q+ +P +S + LL ++ D S RIT+ +I++ P Sbjct: 207 PFDDD----NIRSLLLKVCQGQFEMPS--NISPQAQHLLYRMLDVDSSTRITMEQIREHP 260 Query: 386 W 388 + Sbjct: 261 F 261
>MAPK2_DROME (P49071) MAP kinase-activated protein kinase 2 (EC 2.7.11.1)| (MAPK-activated protein kinase 2) (MAPKAP kinase 2) (MAPKAPK-2) Length = 359 Score = 74.3 bits (181), Expect = 2e-13 Identities = 42/127 (33%), Positives = 63/127 (49%), Gaps = 2/127 (1%) Frame = +2 Query: 14 PTPRVKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVML 193 P +K+ DFG++K + TP Y+APEVL ++YD K D+WS GV +Y+++ Sbjct: 155 PNATLKLTDFGFAKETFTSYTLQTPCYTPYYVAPEVLGPEKYD-KSCDIWSLGVVMYIIM 213 Query: 194 IGSYPFEDPEDPRNFRKTISRILGVQYSIPD--YVRVSSDCRRLLSQIFTADPSKRITIA 367 G PF +RI QY PD + VS + L+ + DPSKR+ I Sbjct: 214 CGFPPFYSNHGLAISPGMKNRIRTGQYDFPDPEWTNVSQAAKDLIKGMLNVDPSKRLRIQ 273 Query: 368 EIKKLPW 388 ++ W Sbjct: 274 DVISNKW 280
>TSSK1_MOUSE (Q61241) Testis-specific serine/threonine-protein kinase 1 (EC| 2.7.11.1) (TSSK-1) (Testis-specific kinase 1) (TSK-1) (Serine/threonine-protein kinase 22A) Length = 364 Score = 74.3 bits (181), Expect = 2e-13 Identities = 52/195 (26%), Positives = 90/195 (46%), Gaps = 29/195 (14%) Frame = +2 Query: 26 VKICDFGYSKSALLHSK-----PKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVM 190 +K+ DFG+SK L K G+ AY APEVL Y KV D+WS GV LY+M Sbjct: 150 IKLSDFGFSKRCLRDDSGRLILSKTFCGSAAYAAPEVLQGIPYQPKVYDIWSLGVILYIM 209 Query: 191 LIGSYPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAE 370 + GS P++D + + R+ + P ++ +C+ L+ ++ D ++R+ I E Sbjct: 210 VCGSMPYDDSNIKKLRIQKEHRV-----NFPRSKHLTGECKDLIYRMLQPDVNRRLHIDE 264 Query: 371 IKKLPWYLKS-----------------------LPKEIAERDRANFKEP-EKATETAASA 478 I W +P+ A++ A EP E+A A S Sbjct: 265 ILNHCWVQPKARGLSSGAINKEGESSRATEPSWIPEPGADKKSATKLEPREEARSEARSE 324 Query: 479 AQPVEEIMRIIQEGQ 523 ++P E+ ++++++ + Sbjct: 325 SKPQEDTLQVVRQSE 339
>ARK1_SCHPO (O59790) Serine/threonine-protein kinase ark1 (EC 2.7.11.1)| (Aurora-related kinase 1) Length = 355 Score = 73.9 bits (180), Expect = 2e-13 Identities = 46/125 (36%), Positives = 70/125 (56%), Gaps = 1/125 (0%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTV-GTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGS 202 +K+ DFG+S A S + T+ GT Y+ PE++ KE+ KV D+WS GV Y L+G+ Sbjct: 226 IKLSDFGWSVHA--PSNRRTTLCGTLDYLPPEMVEGKEHTEKV-DLWSLGVLTYEFLVGA 282 Query: 203 YPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKL 382 PFED T RI V IP + V D R L+S++ +P KR+++ ++ + Sbjct: 283 PPFEDMS---GHSATYKRIAKVDLKIPSF--VPPDARDLISRLLQHNPEKRMSLEQVMRH 337 Query: 383 PWYLK 397 PW +K Sbjct: 338 PWIVK 342
>KAPA_YEAST (P06244) cAMP-dependent protein kinase type 1 (EC 2.7.11.11) (PKA| 1) (CDC25-suppressing protein kinase) (PK-25) Length = 397 Score = 73.9 bits (180), Expect = 2e-13 Identities = 50/146 (34%), Positives = 76/146 (52%), Gaps = 5/146 (3%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSY 205 +KI DFG++K + GTP YIAPEV+S K Y+ K D WS G+ +Y ML G Sbjct: 224 IKITDFGFAK--YVPDVTYTLCGTPDYIAPEVVSTKPYN-KSIDWWSFGILIYEMLAGYT 280 Query: 206 PFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRI-----TIAE 370 PF D N KT +IL + P + + D + LLS++ T D S+R+ + Sbjct: 281 PFYD----SNTMKTYEKILNAELRFPPF--FNEDVKDLLSRLITRDLSQRLGNLQNGTED 334 Query: 371 IKKLPWYLKSLPKEIAERDRANFKEP 448 +K PW+ + + +++ R+ EP Sbjct: 335 VKNHPWFKEVVWEKLLSRNIETPYEP 360
>KC61_SCHPO (Q9UU87) Probable serine/threonine-protein kinase C1919.01 (EC| 2.7.11.1) Length = 354 Score = 73.6 bits (179), Expect = 3e-13 Identities = 45/121 (37%), Positives = 64/121 (52%), Gaps = 2/121 (1%) Frame = +2 Query: 32 ICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSR--KEYDGKVADVWSCGVTLYVMLIGSY 205 + DFG ++ KP GTPA++APE+ K+ GK D+WS GVTLYV+ + Sbjct: 216 VIDFGLAEFLPKDGFVKPASGTPAFMAPELFDNELKKIKGKPLDIWSMGVTLYVIAFAEF 275 Query: 206 PFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLP 385 PF + I+ I G IP Y +SD R+LL + +P KRITI E+ + P Sbjct: 276 PF----NGSTILDMINVIKGKSLMIPAY--CNSDLRKLLERCLEKNPEKRITIEELLRDP 329 Query: 386 W 388 + Sbjct: 330 F 330
>DAPK1_HUMAN (P53355) Death-associated protein kinase 1 (EC 2.7.11.1) (DAP| kinase 1) Length = 1432 Score = 73.6 bits (179), Expect = 3e-13 Identities = 47/155 (30%), Positives = 80/155 (51%), Gaps = 2/155 (1%) Frame = +2 Query: 14 PTPRVKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVML 193 P PR+KI DFG + ++ K GTP ++APE+++ + G AD+WS GV Y++L Sbjct: 153 PKPRIKIIDFGLAHKIDFGNEFKNIFGTPEFVAPEIVNYEPL-GLEADMWSIGVITYILL 211 Query: 194 IGSYPFEDPEDPRNFRKTISRILGVQYSIPD--YVRVSSDCRRLLSQIFTADPSKRITIA 367 G+ PF ++T++ + V Y D + S+ + + ++ DP KR+TI Sbjct: 212 SGASPFLGDTK----QETLANVSAVNYEFEDEYFSNTSALAKDFIRRLLVKDPKKRMTIQ 267 Query: 368 EIKKLPWYLKSLPKEIAERDRANFKEPEKATETAA 472 + + PW +K + A +A+ EK + AA Sbjct: 268 DSLQHPW-IKPKDTQQALSRKASAVNMEKFKKFAA 301
>TSSK6_HUMAN (Q9BXA6) Testis-specific serine/threonine-protein kinase 6 (EC| 2.7.11.1) (TSSK-6) (Small serine/threonine kinase) (Serine/threonine-protein kinase SSTK) Length = 273 Score = 73.2 bits (178), Expect = 4e-13 Identities = 46/128 (35%), Positives = 69/128 (53%), Gaps = 6/128 (4%) Frame = +2 Query: 23 RVKICDFGYSKSALLHSKPKPTV---GTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVML 193 RVK+ DFG+ + A H P + G+ AY +PEVL YD K DVWS GV LYVM+ Sbjct: 149 RVKLTDFGFGRQA--HGYPDLSTTYCGSAAYASPEVLLGIPYDPKKYDVWSMGVVLYVMV 206 Query: 194 IGSYPFEDPED---PRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITI 364 G PF+D + PR ++ GV Y P+ + +S C+ L++++ PS R + Sbjct: 207 TGCMPFDDSDIAGLPRRQKR------GVLY--PEGLELSERCKALIAELLQFSPSARPSA 258 Query: 365 AEIKKLPW 388 ++ + W Sbjct: 259 GQVARNCW 266
>KCC1B_HUMAN (Q6P2M8) Calcium/calmodulin-dependent protein kinase type 1B (EC| 2.7.11.17) (CaM kinase IB) (CaM kinase I beta) (CaMKI-beta) (CaM-KI beta) (Pregnancy up-regulated non-ubiquitously expressed CaM kinase) Length = 343 Score = 73.2 bits (178), Expect = 4e-13 Identities = 47/147 (31%), Positives = 71/147 (48%), Gaps = 8/147 (5%) Frame = +2 Query: 23 RVKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGS 202 ++ + DFG SK + GTP Y+APE+L +K Y GK DVW+ GV Y++L G Sbjct: 152 KIMVSDFGLSKIQA-GNMLGTACGTPGYVAPELLEQKPY-GKAVDVWALGVISYILLCGY 209 Query: 203 YPFEDPEDPRNFRKTISRILGVQYSI--PDYVRVSSDCRRLLSQIFTADPSKRITIAEIK 376 PF D DP F S+IL Y P + +S + + + DP KR T + Sbjct: 210 PPFYDESDPELF----SQILRASYEFDSPFWDDISESAKDFIRHLLERDPQKRFTCQQAL 265 Query: 377 KLPW------YLKSLPKEIAERDRANF 439 + W + + + ++E+ R NF Sbjct: 266 RHLWISGDTAFDRDILGSVSEQIRKNF 292
>KS6A1_MOUSE (P18653) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1) (S6K-alpha| 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 724 Score = 73.2 bits (178), Expect = 4e-13 Identities = 53/177 (29%), Positives = 97/177 (54%), Gaps = 8/177 (4%) Frame = +2 Query: 2 LDGSPTPR-VKICDFGYSKSALLHSKPKPT-VGTPAYIAPEVLSRKEYDGKVADVWSCGV 175 +D S P ++ICDFG++K + T T ++APEVL R+ YD + D+WS G+ Sbjct: 533 VDESGNPECLRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYD-EGCDIWSLGI 591 Query: 176 TLYVMLIGSYPFED-PEDPRNFRKTISRILGVQYSIP--DYVRVSSDCRRLLSQIFTADP 346 LY ML G PF + P D + ++RI ++++ ++ VS + L+S++ DP Sbjct: 592 LLYTMLAGYTPFANGPSDTP--EEILTRIGSGKFTLSGGNWNTVSETAKDLVSKMLHVDP 649 Query: 347 SKRITIAEIKKLPWYLK--SLPK-EIAERDRANFKEPEKATETAASAAQPVEEIMRI 508 +R+T ++ + PW + LP+ +++ +D K AT +A ++++P ++ I Sbjct: 650 HQRLTAKQVLQHPWITQKDKLPQSQLSHQDLQLVKGAMAATYSALNSSKPTPQLKPI 706 Score = 48.5 bits (114), Expect = 1e-05 Identities = 35/112 (31%), Positives = 62/112 (55%), Gaps = 1/112 (0%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPT-VGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGS 202 +K+ DFG SK A+ H K + GT Y+APEV++R+ + AD WS GV L+G Sbjct: 201 IKLTDFGLSKEAIDHEKKAYSFCGTVEYMAPEVVNRQGHTHS-ADWWSYGV-----LMG- 253 Query: 203 YPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRI 358 ++ ++T++ IL + +P + +S++ + LL +F +P+ R+ Sbjct: 254 ---------KDRKETMTLILKAKLGMPQF--LSTEAQSLLRALFKRNPANRL 294
>KS6A1_HUMAN (Q15418) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1) (S6K-alpha| 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 735 Score = 73.2 bits (178), Expect = 4e-13 Identities = 53/177 (29%), Positives = 97/177 (54%), Gaps = 8/177 (4%) Frame = +2 Query: 2 LDGSPTPR-VKICDFGYSKSALLHSKPKPT-VGTPAYIAPEVLSRKEYDGKVADVWSCGV 175 +D S P ++ICDFG++K + T T ++APEVL R+ YD + D+WS G+ Sbjct: 544 VDESGNPECLRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYD-EGCDIWSLGI 602 Query: 176 TLYVMLIGSYPFED-PEDPRNFRKTISRILGVQYSIP--DYVRVSSDCRRLLSQIFTADP 346 LY ML G PF + P D + ++RI ++++ ++ VS + L+S++ DP Sbjct: 603 LLYTMLAGYTPFANGPSDTP--EEILTRIGSGKFTLSGGNWNTVSETAKDLVSKMLHVDP 660 Query: 347 SKRITIAEIKKLPWYLK--SLPK-EIAERDRANFKEPEKATETAASAAQPVEEIMRI 508 +R+T ++ + PW + LP+ +++ +D K AT +A ++++P ++ I Sbjct: 661 HQRLTAKQVLQHPWVTQKDKLPQSQLSHQDLQLVKGAMAATYSALNSSKPTPQLKPI 717 Score = 65.9 bits (159), Expect = 7e-11 Identities = 39/112 (34%), Positives = 68/112 (60%), Gaps = 1/112 (0%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTV-GTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGS 202 +K+ DFG SK A+ H K + GT Y+APEV++R+ + AD WS GV ++ ML GS Sbjct: 201 IKLTDFGLSKEAIDHEKKAYSFCGTVEYMAPEVVNRQGHSHS-ADWWSYGVLMFEMLTGS 259 Query: 203 YPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRI 358 PF+ ++ ++T++ IL + +P + +S++ + LL +F +P+ R+ Sbjct: 260 LPFQG----KDRKETMTLILKAKLGMPQF--LSTEAQSLLRALFKRNPANRL 305
>KPSH1_MOUSE (Q91YA2) Serine/threonine-protein kinase H1 (EC 2.7.11.1) (PSK-H1)| Length = 423 Score = 73.2 bits (178), Expect = 4e-13 Identities = 46/126 (36%), Positives = 67/126 (53%), Gaps = 4/126 (3%) Frame = +2 Query: 23 RVKICDFGYSKSALLHSK--PKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLI 196 ++ I DFG + + K T GTP YIAPEVL RK Y V D+W+ GV Y++L Sbjct: 233 KIIITDFGLASARKKGDDCLMKTTCGTPEYIAPEVLVRKPYTNSV-DMWALGVIAYILLS 291 Query: 197 GSYPFEDPEDPRNFRKTISRILGVQYSI--PDYVRVSSDCRRLLSQIFTADPSKRITIAE 370 G+ PFED R +R +IL +YS + VS+ + + ++ T DP R+T + Sbjct: 292 GTMPFEDDNRTRLYR----QILRGKYSYLGEPWPSVSNLAKDFIDRLLTVDPGARMTALQ 347 Query: 371 IKKLPW 388 + PW Sbjct: 348 ALRHPW 353
>CHK1_CHICK (Q8AYC9) Serine/threonine-protein kinase Chk1 (EC 2.7.11.1)| Length = 476 Score = 72.8 bits (177), Expect = 5e-13 Identities = 45/132 (34%), Positives = 69/132 (52%), Gaps = 4/132 (3%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPK---PTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLI 196 +KI DFG + + + + GT Y+APE+L R E+ + DVW+CGV L ML Sbjct: 144 LKISDFGLATVFKHNGRERLLNKMCGTLPYVAPELLRRPEFRAEPVDVWACGVVLTAMLA 203 Query: 197 GSYPFEDPEDP-RNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEI 373 G P++ P D + + R + + + ++ S LL +I T +P+ RITI +I Sbjct: 204 GELPWDQPSDSCQEYSDWKER----KTYLAPWRKIDSAPLALLHKILTENPTARITIPDI 259 Query: 374 KKLPWYLKSLPK 409 KK WY + L K Sbjct: 260 KKDRWYCRPLKK 271
>STK6_RAT (P59241) Serine/threonine-protein kinase 6 (EC 2.7.11.1) (Aurora-A)| (ratAurA) Length = 397 Score = 72.8 bits (177), Expect = 5e-13 Identities = 44/121 (36%), Positives = 70/121 (57%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSY 205 +KI DFG+S A S+ GT Y PE++ + +D KV D+WS GV Y L+G Sbjct: 263 LKIADFGWSVHAP-SSRRTTLCGTLDYQPPEMIEGRMHDEKV-DLWSLGVLCYEFLVGMP 320 Query: 206 PFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLP 385 PFE +++T RI V+++ PD+V + R L+S++ + S+R+T+AE+ + P Sbjct: 321 PFE----AHTYQETYRRISRVEFTFPDFV--TEGARDLISRLLKHNSSQRLTLAEVLEHP 374 Query: 386 W 388 W Sbjct: 375 W 375
>TSSK1_HUMAN (Q9BXA7) Testis-specific serine/threonine-protein kinase 1 (EC| 2.7.11.1) (TSSK-1) (Testis-specific kinase 1) (TSK-1) (Serine/threonine-protein kinase 22A) Length = 367 Score = 72.8 bits (177), Expect = 5e-13 Identities = 42/126 (33%), Positives = 64/126 (50%), Gaps = 5/126 (3%) Frame = +2 Query: 26 VKICDFGYSKSALLHSK-----PKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVM 190 +K+ DF +SK L K G+PAY APEVL Y KV D+WS GV LY+M Sbjct: 150 IKLSDFSFSKRCLRDDSGRMALSKTFCGSPAYAAPEVLQGIPYQPKVYDIWSLGVILYIM 209 Query: 191 LIGSYPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAE 370 + GS P++D N +K + + + P ++ +C+ L+ + D ++R+ I E Sbjct: 210 VCGSMPYDD----SNIKKMLRIQKEHRVNFPRSKHLTGECKDLIYHMLQPDVNRRLHIDE 265 Query: 371 IKKLPW 388 I W Sbjct: 266 ILSHCW 271
>TSSK2_MOUSE (O54863) Testis-specific serine/threonine-protein kinase 2 (EC| 2.7.11.1) (TSSK-2) (Testis-specific kinase 2) (TSK-2) (Serine/threonine-protein kinase 22B) Length = 357 Score = 72.8 bits (177), Expect = 5e-13 Identities = 46/144 (31%), Positives = 71/144 (49%), Gaps = 5/144 (3%) Frame = +2 Query: 26 VKICDFGYSKSALLHSK-----PKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVM 190 +K+ DFG+SK L K G+ AY APEV Y KV D+WS GV LY+M Sbjct: 150 IKLSDFGFSKGCLRDGSGRIVLSKTFCGSAAYAAPEVRQGIPYQPKVYDIWSLGVILYIM 209 Query: 191 LIGSYPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAE 370 + GS P++D + + + R+ P ++ +C+ L+ +I D ++R+ I E Sbjct: 210 VCGSMPYDDSDIKKLRIQKEHRV-----DFPRSKNLTGECKDLIYRILQPDVNRRLHIDE 264 Query: 371 IKKLPWYLKSLPKEIAERDRANFK 442 I W PK ++ A+FK Sbjct: 265 ILSHSWLQPPKPKAMSS---ASFK 285
>KCC4_RAT (P13234) Calcium/calmodulin-dependent protein kinase type IV (EC| 2.7.11.17) (CAM kinase-GR) (CaMK IV) (Calspermin) Length = 474 Score = 72.4 bits (176), Expect = 7e-13 Identities = 45/128 (35%), Positives = 63/128 (49%), Gaps = 2/128 (1%) Frame = +2 Query: 11 SPTPRVKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVM 190 +P +KI DFG SK K GTP Y APE+L Y G D+WS G+ Y++ Sbjct: 172 APDAPLKIADFGLSKIVEHQVLMKTVCGTPGYCAPEILRGCAY-GPEVDMWSVGIITYIL 230 Query: 191 LIGSYPFEDPEDPRNFRKTISRILGVQYSI--PDYVRVSSDCRRLLSQIFTADPSKRITI 364 L G PF D R + RIL +Y P + VS + + L+ ++ DP KR+T Sbjct: 231 LCGFEPF---YDERGDQFMFRRILNCEYYFISPWWDEVSLNAKDLVKKLIVLDPKKRLTT 287 Query: 365 AEIKKLPW 388 + + PW Sbjct: 288 FQALQHPW 295
>STK6_HUMAN (O14965) Serine/threonine-protein kinase 6 (EC 2.7.11.1)| (Serine/threonine kinase 15) (Aurora/IPL1-related kinase 1) (Aurora-related kinase 1) (hARK1) (Aurora-A) (Breast-tumor-amplified kinase) Length = 403 Score = 72.4 bits (176), Expect = 7e-13 Identities = 43/121 (35%), Positives = 69/121 (57%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSY 205 +KI DFG+S A S+ GT Y+ PE++ + +D KV D+WS GV Y L+G Sbjct: 270 LKIADFGWSVHAP-SSRRTTLCGTLDYLPPEMIEGRMHDEKV-DLWSLGVLCYEFLVGKP 327 Query: 206 PFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLP 385 PFE +++T RI V+++ PD+ V+ R L+S++ +PS+R + E+ + P Sbjct: 328 PFE----ANTYQETYKRISRVEFTFPDF--VTEGARDLISRLLKHNPSQRPMLREVLEHP 381 Query: 386 W 388 W Sbjct: 382 W 382
>KCC4_MOUSE (P08414) Calcium/calmodulin-dependent protein kinase type IV (EC| 2.7.11.17) (CAM kinase-GR) (CaMK IV) Length = 469 Score = 72.4 bits (176), Expect = 7e-13 Identities = 45/128 (35%), Positives = 63/128 (49%), Gaps = 2/128 (1%) Frame = +2 Query: 11 SPTPRVKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVM 190 +P +KI DFG SK K GTP Y APE+L Y G D+WS G+ Y++ Sbjct: 172 APDAPLKIADFGLSKIVEHQVLMKTVCGTPGYCAPEILRGCAY-GPEVDMWSVGIITYIL 230 Query: 191 LIGSYPFEDPEDPRNFRKTISRILGVQYSI--PDYVRVSSDCRRLLSQIFTADPSKRITI 364 L G PF D R + RIL +Y P + VS + + L+ ++ DP KR+T Sbjct: 231 LCGFEPF---YDERGDQFMFRRILNCEYYFISPWWDEVSLNAKDLVKKLIVLDPKKRLTT 287 Query: 365 AEIKKLPW 388 + + PW Sbjct: 288 FQALQHPW 295
>KKCC1_MOUSE (Q8VBY2) Calcium/calmodulin-dependent protein kinase kinase 1 (EC| 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase alpha) (CaM-kinase kinase alpha) (CaM-KK alpha) (CaMKK alpha) (CaMKK 1) (CaM-kinase IV kinase) Length = 505 Score = 72.0 bits (175), Expect = 9e-13 Identities = 46/128 (35%), Positives = 68/128 (53%), Gaps = 4/128 (3%) Frame = +2 Query: 26 VKICDFGYSKSALLH-SKPKPTVGTPAYIAPEVLSR--KEYDGKVADVWSCGVTLYVMLI 196 VKI DFG S + ++ T GTPA++APE +S + + GK DVW+ GVTLY + Sbjct: 289 VKIADFGVSNQFEGNDAQLSSTAGTPAFMAPEAISDSGQSFSGKALDVWATGVTLYCFVY 348 Query: 197 GSYPFEDPEDPRNFRKTISR-ILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEI 373 G PF D ++ T+ R I P+ VS D + L+ ++ +P RI +++I Sbjct: 349 GKCPFID-----DYILTLHRKIKNEAVVFPEEPEVSEDLKDLILRMLDKNPETRIGVSDI 403 Query: 374 KKLPWYLK 397 K PW K Sbjct: 404 KLHPWVTK 411
>KS6A2_MOUSE (Q9WUT3) Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1)| (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (Protein-tyrosine kinase Mpk-9) (MAP kinase-activated protein kinase 1c) (M Length = 733 Score = 72.0 bits (175), Expect = 9e-13 Identities = 45/134 (33%), Positives = 75/134 (55%), Gaps = 5/134 (3%) Frame = +2 Query: 2 LDGSPTPR-VKICDFGYSKSALLHSKPKPT-VGTPAYIAPEVLSRKEYDGKVADVWSCGV 175 +D S P ++ICDFG++K + T T ++APEVL R+ YD DVWS G+ Sbjct: 541 MDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDA-ACDVWSLGI 599 Query: 176 TLYVMLIGSYPFED-PEDPRNFRKTISRILGVQYSIP--DYVRVSSDCRRLLSQIFTADP 346 LY ML G PF + P+D + ++RI +Y++ ++ +S + ++S++ DP Sbjct: 600 LLYTMLAGFTPFANGPDDTP--EEILARIGSGKYALSGGNWDSISDAAKDVVSKMLHVDP 657 Query: 347 SKRITIAEIKKLPW 388 +R+T ++ K PW Sbjct: 658 QQRLTAVQVLKHPW 671 Score = 67.8 bits (164), Expect = 2e-11 Identities = 44/129 (34%), Positives = 76/129 (58%), Gaps = 6/129 (4%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTV-GTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGS 202 +KI DFG SK A H K + GT Y+APEV++R+ + + AD WS GV ++ ML GS Sbjct: 198 IKITDFGLSKEATDHDKRAYSFCGTIEYMAPEVVNRRGHT-QSADWWSFGVLMFEMLTGS 256 Query: 203 YPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRI-----TIA 367 PF+ ++ ++T++ IL + +P + +S++ + LL +F +P R+ + Sbjct: 257 LPFQG----KDRKETMALILKAKLGMPQF--LSAEAQSLLRALFKRNPCNRLGAGVDGVE 310 Query: 368 EIKKLPWYL 394 EIK+ P+++ Sbjct: 311 EIKRHPFFV 319
>KCC4_HUMAN (Q16566) Calcium/calmodulin-dependent protein kinase type IV (EC| 2.7.11.17) (CAM kinase-GR) (CaMK IV) Length = 473 Score = 72.0 bits (175), Expect = 9e-13 Identities = 45/128 (35%), Positives = 63/128 (49%), Gaps = 2/128 (1%) Frame = +2 Query: 11 SPTPRVKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVM 190 +P +KI DFG SK K GTP Y APE+L Y G D+WS G+ Y++ Sbjct: 176 APDAPLKIADFGLSKIVEHQVLMKTVCGTPGYCAPEILRGCAY-GPEVDMWSVGIITYIL 234 Query: 191 LIGSYPFEDPEDPRNFRKTISRILGVQYSI--PDYVRVSSDCRRLLSQIFTADPSKRITI 364 L G PF D R + RIL +Y P + VS + + L+ ++ DP KR+T Sbjct: 235 LCGFEPF---YDERGDQFMFRRILNCEYYFISPWWDEVSLNAKDLVRKLIVLDPKKRLTT 291 Query: 365 AEIKKLPW 388 + + PW Sbjct: 292 FQALQHPW 299
>DAPK1_MOUSE (Q80YE7) Death-associated protein kinase 1 (EC 2.7.11.1) (DAP| kinase 1) Length = 1442 Score = 71.6 bits (174), Expect = 1e-12 Identities = 46/155 (29%), Positives = 80/155 (51%), Gaps = 2/155 (1%) Frame = +2 Query: 14 PTPRVKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVML 193 P PR+KI DFG + ++ K GTP ++APE+++ + G AD+WS GV Y++L Sbjct: 153 PKPRIKIIDFGLAHKIDFGNEFKNIFGTPEFVAPEIVNYEPL-GLEADMWSIGVITYILL 211 Query: 194 IGSYPFEDPEDPRNFRKTISRILGVQYSIPD--YVRVSSDCRRLLSQIFTADPSKRITIA 367 G+ PF ++T++ + V Y + + S+ + + ++ DP KR+TI Sbjct: 212 SGASPFLGDTK----QETLANVSAVNYDFEEEFFRNTSTLAKDFIRRLLVKDPKKRMTIQ 267 Query: 368 EIKKLPWYLKSLPKEIAERDRANFKEPEKATETAA 472 + + PW +K + A +A+ EK + AA Sbjct: 268 DSLQHPW-IKPKDTQQALSRKASAVNMEKFKKFAA 301
>CDPK2_PLAF7 (Q8ICR0) Calcium-dependent protein kinase 2 (EC 2.7.11.1) (PfCDPK2)| Length = 508 Score = 71.6 bits (174), Expect = 1e-12 Identities = 44/121 (36%), Positives = 63/121 (52%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSY 205 +KI DFG SK+ GTP Y+AP+VL K YD K D+WS GV +Y +L G Sbjct: 208 LKIIDFGLSKNLGTGEFTTTKAGTPYYVAPQVLDGK-YDKK-CDIWSSGVIMYTLLCGYP 265 Query: 206 PFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLP 385 PF D +K + D+ +SSD + L++++ T +P++R TI E P Sbjct: 266 PFYGDTDNEVLKKVKKGEFCFYEN--DWGSISSDAKNLITKLLTYNPNERCTIEEALNHP 323 Query: 386 W 388 W Sbjct: 324 W 324
>CDPK2_PLAFK (O15865) Calcium-dependent protein kinase 2 (EC 2.7.11.1) (PfCDPK2)| Length = 512 Score = 71.6 bits (174), Expect = 1e-12 Identities = 44/121 (36%), Positives = 63/121 (52%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSY 205 +KI DFG SK+ GTP Y+AP+VL K YD K D+WS GV +Y +L G Sbjct: 208 LKIIDFGLSKNLGTGEFTTTKAGTPYYVAPQVLDGK-YDKK-CDIWSSGVIMYTLLCGYP 265 Query: 206 PFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLP 385 PF D +K + D+ +SSD + L++++ T +P++R TI E P Sbjct: 266 PFYGDTDNEVLKKVKKGEFCFYEN--DWGSISSDAKNLITKLLTYNPNERCTIEEALNHP 323 Query: 386 W 388 W Sbjct: 324 W 324
>TSSK4_MOUSE (Q9D411) Testis-specific serine/threonine-protein kinase 4 (EC| 2.7.11.1) (TSSK-4) (Testis-specific kinase 4) (TSK-4) Length = 328 Score = 71.2 bits (173), Expect = 2e-12 Identities = 44/145 (30%), Positives = 73/145 (50%), Gaps = 16/145 (11%) Frame = +2 Query: 26 VKICDFGYSK----SALLHSKP------------KPTVGTPAYIAPEVLSRKEYDGKVAD 157 VKI DFG++K S +HS P + G+ AY PE+L Y+ ++D Sbjct: 162 VKISDFGFAKMVPSSQPVHSSPSYRQMNSLSHLSQTYCGSFAYACPEILLGLPYNPFLSD 221 Query: 158 VWSCGVTLYVMLIGSYPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFT 337 WS GV LY +++ PF+D + R+T + + P + +S +C+ L+ Q+ Sbjct: 222 TWSMGVILYTLVVARLPFDDTNLKKLLRETQKEV-----TFPANLTISQECKNLILQLL- 275 Query: 338 ADPSKRITIAEIKKLPWYLKSLPKE 412 +KR TI ++ + PW LK P++ Sbjct: 276 RQSTKRATILDVLRDPWMLKFQPEQ 300
>KCC1B_RAT (O70150) Calcium/calmodulin-dependent protein kinase type 1B (EC| 2.7.11.17) (CaM kinase IB) (CaM kinase I beta) (CaMKI-beta) (CaM-KI beta) (Pregnancy up-regulated non-ubiquitously expressed CaM kinase homolog) Length = 343 Score = 71.2 bits (173), Expect = 2e-12 Identities = 43/124 (34%), Positives = 61/124 (49%), Gaps = 2/124 (1%) Frame = +2 Query: 23 RVKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGS 202 ++ + DFG SK + GTP Y+APE+L +K Y GK DVW+ GV Y++L G Sbjct: 152 KIMVSDFGLSKIQA-GNMLGTACGTPGYVAPELLEQKPY-GKAVDVWALGVISYILLCGY 209 Query: 203 YPFEDPEDPRNFRKTISRILGVQYSI--PDYVRVSSDCRRLLSQIFTADPSKRITIAEIK 376 PF D DP F S+IL Y P + +S + + + DP KR T + Sbjct: 210 PPFYDESDPELF----SQILRASYEFDSPFWDDISESAKDFIRHLLERDPQKRFTCQQAL 265 Query: 377 KLPW 388 + W Sbjct: 266 QHLW 269
>KCC1B_MOUSE (Q9QYK9) Calcium/calmodulin-dependent protein kinase type 1B (EC| 2.7.11.17) (CaM kinase IB) (CaM kinase I beta) (CaMKI-beta) (CaM-KI beta) (Pregnancy up-regulated non-ubiquitously expressed CaM kinase homolog) Length = 343 Score = 71.2 bits (173), Expect = 2e-12 Identities = 43/124 (34%), Positives = 61/124 (49%), Gaps = 2/124 (1%) Frame = +2 Query: 23 RVKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGS 202 ++ + DFG SK + GTP Y+APE+L +K Y GK DVW+ GV Y++L G Sbjct: 152 KIMVSDFGLSKIQA-GNMLGTACGTPGYVAPELLEQKPY-GKAVDVWALGVISYILLCGY 209 Query: 203 YPFEDPEDPRNFRKTISRILGVQYSI--PDYVRVSSDCRRLLSQIFTADPSKRITIAEIK 376 PF D DP F S+IL Y P + +S + + + DP KR T + Sbjct: 210 PPFYDESDPELF----SQILRASYEFDSPFWDDISESAKDFIRHLLERDPQKRFTCQQAL 265 Query: 377 KLPW 388 + W Sbjct: 266 QHLW 269
>IPL1_YEAST (P38991) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) (Increase-in-ploidy protein 1) Length = 367 Score = 71.2 bits (173), Expect = 2e-12 Identities = 37/127 (29%), Positives = 68/127 (53%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSY 205 +K+ DFG+S ++ K GT Y++PE++ +EYD + D W+ GV + +L G+ Sbjct: 241 IKLTDFGWSIINPPENRRKTVCGTIDYLSPEMVESREYDHTI-DAWALGVLAFELLTGAP 299 Query: 206 PFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLP 385 PFE+ ++ RI + +P +S D + L+ ++ DP R+ + ++K P Sbjct: 300 PFEEEMKDTTYK----RIAALDIKMPS--NISQDAQDLILKLLKYDPKDRMRLGDVKMHP 353 Query: 386 WYLKSLP 406 W L++ P Sbjct: 354 WILRNKP 360
>KAPB_YEAST (P06245) cAMP-dependent protein kinase type 2 (EC 2.7.11.11) (PKA| 2) Length = 380 Score = 71.2 bits (173), Expect = 2e-12 Identities = 50/147 (34%), Positives = 76/147 (51%), Gaps = 6/147 (4%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSY 205 +KI DFG++K + + GTP YIAPEV++ K Y+ K D WS GV +Y ML G Sbjct: 207 IKITDFGFAKE--VQTVTWTLCGTPDYIAPEVITTKPYN-KSVDWWSLGVLIYEMLAGYT 263 Query: 206 PFEDPEDPRNFRKTI-SRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRI-----TIA 367 PF D + + K + +++ Y PD V LLS++ TAD ++RI Sbjct: 264 PFYDTTPMKTYEKILQGKVVYPPYFHPDVV-------DLLSKLITADLTRRIGNLQSGSR 316 Query: 368 EIKKLPWYLKSLPKEIAERDRANFKEP 448 +IK PW+ + + + + +D EP Sbjct: 317 DIKAHPWFSEVVWERLLAKDIETPYEP 343
>TRIB3_HUMAN (Q96RU7) Tribbles homolog 3 (TRB-3) (Neuronal cell death-inducible| putative kinase) (p65-interacting inhibitor of NF-kappaB) (SINK) Length = 358 Score = 70.9 bits (172), Expect = 2e-12 Identities = 44/108 (40%), Positives = 60/108 (55%), Gaps = 1/108 (0%) Frame = +2 Query: 98 PAYIAPEVLS-RKEYDGKVADVWSCGVTLYVMLIGSYPFEDPEDPRNFRKTISRILGVQY 274 PAY+ PE+LS R Y GK ADVWS GV L+ ML G YPF+D E F K I Y Sbjct: 223 PAYVGPEILSSRASYSGKAADVWSLGVALFTMLAGHYPFQDSEPVLLFGK----IRRGAY 278 Query: 275 SIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLPWYLKSLPKEIA 418 ++P +S+ R L+ + +P++R+T I PW L+ P +A Sbjct: 279 ALP--AGLSAPARCLVRCLLRREPAERLTATGILLHPW-LRQDPMPLA 323
>STK6L_XENLA (Q91819) Serine/threonine-protein kinase Eg2-like (EC 2.7.11.1)| (p46XlEg22) Length = 408 Score = 70.9 bits (172), Expect = 2e-12 Identities = 48/151 (31%), Positives = 76/151 (50%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSY 205 +KI DFG+S A S+ GT Y+ PE++ + +D KV D+WS GV Y L+G Sbjct: 277 LKIADFGWSVHAP-SSRRTTLCGTLDYLPPEMIEGRMHDEKV-DLWSLGVLCYEFLVGKP 334 Query: 206 PFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLP 385 PFE +R RI V++ P Y VS + + L+S++ +P+ R+ + + + P Sbjct: 335 PFETDTHQETYR----RISKVEFQYPPY--VSEEAKDLVSKLLKHNPNHRLPLKGVLEHP 388 Query: 386 WYLKSLPKEIAERDRANFKEPEKATETAASA 478 W +K N ++P+K E A A Sbjct: 389 WIVK------------NSQQPKKKDEPLAGA 407
>PLK1_RAT (Q62673) Serine/threonine-protein kinase PLK1 (EC 2.7.11.21)| (Polo-like kinase 1) (PLK-1) Length = 603 Score = 70.9 bits (172), Expect = 2e-12 Identities = 46/117 (39%), Positives = 66/117 (56%), Gaps = 1/117 (0%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTV-GTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGS 202 VKI DFG + + K T+ GTP YIAPEVLS+K + +V DVWS G +Y +L+G Sbjct: 190 VKIGDFGLATKVEYEGERKKTLCGTPNYIAPEVLSKKGHSFEV-DVWSIGCIMYTLLVGK 248 Query: 203 YPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEI 373 PFE ++T RI +YSIP + ++ L+ ++ DP+ R TI E+ Sbjct: 249 PPFE----TSCLKETYLRIKKNEYSIPKH--INPVAASLIQKMLQTDPAARPTIHEL 299
>PLK1_MOUSE (Q07832) Serine/threonine-protein kinase PLK1 (EC 2.7.11.21)| (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13) Length = 603 Score = 70.9 bits (172), Expect = 2e-12 Identities = 46/117 (39%), Positives = 66/117 (56%), Gaps = 1/117 (0%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTV-GTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGS 202 VKI DFG + + K T+ GTP YIAPEVLS+K + +V DVWS G +Y +L+G Sbjct: 190 VKIGDFGLATKVEYEGERKKTLCGTPNYIAPEVLSKKGHSFEV-DVWSIGCIMYTLLVGK 248 Query: 203 YPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEI 373 PFE ++T RI +YSIP + ++ L+ ++ DP+ R TI E+ Sbjct: 249 PPFE----TSCLKETYLRIKKNEYSIPKH--INPVAASLIQKMLQTDPTARPTIHEL 299
>CDC5_YEAST (P32562) Cell cycle serine/threonine-protein kinase CDC5/MSD2 (EC| 2.7.11.21) Length = 705 Score = 70.9 bits (172), Expect = 2e-12 Identities = 47/132 (35%), Positives = 66/132 (50%), Gaps = 2/132 (1%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTV-GTPAYIAPEVLSRKEYDGKV-ADVWSCGVTLYVMLIG 199 +KI DFG + S+ K T+ GTP YIAPEVL K D+WS GV LY +LIG Sbjct: 218 LKIGDFGLAAVLANESERKYTICGTPNYIAPEVLMGKHSGHSFEVDIWSLGVMLYALLIG 277 Query: 200 SYPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKK 379 PF+ R+ RI +S P +S + + L+ I + DP +R ++ EI Sbjct: 278 KPPFQ----ARDVNTIYERIKCRDFSFPRDKPISDEGKILIRDILSLDPIERPSLTEIMD 333 Query: 380 LPWYLKSLPKEI 415 W+ + P I Sbjct: 334 YVWFRGTFPPSI 345
>PLK1_HUMAN (P53350) Serine/threonine-protein kinase PLK1 (EC 2.7.11.21)| (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13) Length = 603 Score = 70.5 bits (171), Expect = 3e-12 Identities = 46/117 (39%), Positives = 66/117 (56%), Gaps = 1/117 (0%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTV-GTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGS 202 VKI DFG + + K T+ GTP YIAPEVLS+K + +V DVWS G +Y +L+G Sbjct: 190 VKIGDFGLATKVEYDGERKKTLCGTPNYIAPEVLSKKGHSFEV-DVWSIGCIMYTLLVGK 248 Query: 203 YPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEI 373 PFE ++T RI +YSIP + ++ L+ ++ DP+ R TI E+ Sbjct: 249 PPFE----TSCLKETYLRIKKNEYSIPKH--INPVAASLIQKMLQTDPTARPTINEL 299
>KKCC1_HUMAN (Q8N5S9) Calcium/calmodulin-dependent protein kinase kinase 1 (EC| 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase alpha) (CaM-kinase kinase alpha) (CaM-KK alpha) (CaMKK alpha) (CaMKK 1) (CaM-kinase IV kinase) Length = 505 Score = 70.5 bits (171), Expect = 3e-12 Identities = 51/160 (31%), Positives = 74/160 (46%), Gaps = 3/160 (1%) Frame = +2 Query: 26 VKICDFGYSKSALLH-SKPKPTVGTPAYIAPEVLSR--KEYDGKVADVWSCGVTLYVMLI 196 VKI DFG S + ++ T GTPA++APE +S + + GK DVW+ GVTLY + Sbjct: 289 VKIADFGVSNQFEGNDAQLSSTAGTPAFMAPEAISDSGQSFSGKALDVWATGVTLYCFVY 348 Query: 197 GSYPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIK 376 G PF D RK I P+ +S + + L+ ++ +P RI + +IK Sbjct: 349 GKCPFIDDFILALHRK----IKNEPVVFPEEPEISEELKDLILKMLDKNPETRIGVPDIK 404 Query: 377 KLPWYLKSLPKEIAERDRANFKEPEKATETAASAAQPVEE 496 PW K N +EP + E S + EE Sbjct: 405 LHPWVTK------------NGEEPLPSEEEHCSVVEVTEE 432
>KS6A2_HUMAN (Q15349) Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1)| (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (MAP kinase-activated protein kinase 1c) (MAPKAPK1C) Length = 733 Score = 70.5 bits (171), Expect = 3e-12 Identities = 45/147 (30%), Positives = 81/147 (55%), Gaps = 7/147 (4%) Frame = +2 Query: 8 GSPTPRVKICDFGYSKSALLHSKPKPT-VGTPAYIAPEVLSRKEYDGKVADVWSCGVTLY 184 GSP +++CDFG++K + T T ++APEVL R+ YD D+WS G+ LY Sbjct: 545 GSPES-IRVCDFGFAKQLRAGNGLLMTPCYTANFVAPEVLKRQGYDA-ACDIWSLGILLY 602 Query: 185 VMLIGSYPFED-PEDPRNFRKTISRILGVQYSIP--DYVRVSSDCRRLLSQIFTADPSKR 355 ML G PF + P+D + ++RI +Y++ ++ +S + ++S++ DP +R Sbjct: 603 TMLAGFTPFANGPDDTP--EEILARIGSGKYALSGGNWDSISDAAKDVVSKMLHVDPHQR 660 Query: 356 ITIAEIKKLPWYLKS---LPKEIAERD 427 +T ++ K PW + P +++ +D Sbjct: 661 LTAMQVLKHPWVVNREYLSPNQLSRQD 687 Score = 68.6 bits (166), Expect = 1e-11 Identities = 44/129 (34%), Positives = 76/129 (58%), Gaps = 6/129 (4%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTV-GTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGS 202 +KI DFG SK A+ H K + GT Y+APEV++R+ + + AD WS GV ++ ML GS Sbjct: 198 IKITDFGLSKEAIDHDKRAYSFCGTIEYMAPEVVNRRGHT-QSADWWSFGVLMFEMLTGS 256 Query: 203 YPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRI-----TIA 367 PF+ ++ ++T++ IL + +P + +S + + LL +F +P R+ + Sbjct: 257 LPFQG----KDRKETMALILKAKLGMPQF--LSGEAQSLLRALFKRNPCNRLGAGIDGVE 310 Query: 368 EIKKLPWYL 394 EIK+ P+++ Sbjct: 311 EIKRHPFFV 319
>KS6A3_MOUSE (P18654) Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1)| (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (MAP kinase-activated protein kinase 1b) (MAPKAPK1B) Length = 740 Score = 70.5 bits (171), Expect = 3e-12 Identities = 47/134 (35%), Positives = 74/134 (55%), Gaps = 5/134 (3%) Frame = +2 Query: 2 LDGSPTPR-VKICDFGYSKSALLHSKPKPT-VGTPAYIAPEVLSRKEYDGKVADVWSCGV 175 +D S P ++ICDFG++K + T T ++APEVL R+ YD D+WS GV Sbjct: 548 VDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDA-ACDIWSLGV 606 Query: 176 TLYVMLIGSYPFED-PEDPRNFRKTISRILGVQYSIPD--YVRVSSDCRRLLSQIFTADP 346 LY ML G PF + P+D + ++RI ++S+ + VS + L+S++ DP Sbjct: 607 LLYTMLTGYTPFANGPDDTP--EEILARIGSGKFSLSGGYWNSVSDTAKDLVSKMLHVDP 664 Query: 347 SKRITIAEIKKLPW 388 +R+T A + + PW Sbjct: 665 HQRLTAALVLRHPW 678 Score = 63.9 bits (154), Expect = 3e-10 Identities = 37/112 (33%), Positives = 68/112 (60%), Gaps = 1/112 (0%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTV-GTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGS 202 +K+ DFG SK ++ H K + GT Y+APEV++R+ + + AD WS GV ++ ML G+ Sbjct: 207 IKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNRRGHT-QSADWWSFGVLMFEMLTGT 265 Query: 203 YPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRI 358 PF+ ++ ++T++ IL + +P + +S + + LL +F +P+ R+ Sbjct: 266 LPFQG----KDRKETMTMILKAKLGMPQF--LSPEAQSLLRMLFKRNPANRL 311
>KS6A3_HUMAN (P51812) Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1)| (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protei Length = 740 Score = 70.5 bits (171), Expect = 3e-12 Identities = 47/134 (35%), Positives = 74/134 (55%), Gaps = 5/134 (3%) Frame = +2 Query: 2 LDGSPTPR-VKICDFGYSKSALLHSKPKPT-VGTPAYIAPEVLSRKEYDGKVADVWSCGV 175 +D S P ++ICDFG++K + T T ++APEVL R+ YD D+WS GV Sbjct: 548 VDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDA-ACDIWSLGV 606 Query: 176 TLYVMLIGSYPFED-PEDPRNFRKTISRILGVQYSIPD--YVRVSSDCRRLLSQIFTADP 346 LY ML G PF + P+D + ++RI ++S+ + VS + L+S++ DP Sbjct: 607 LLYTMLTGYTPFANGPDDTP--EEILARIGSGKFSLSGGYWNSVSDTAKDLVSKMLHVDP 664 Query: 347 SKRITIAEIKKLPW 388 +R+T A + + PW Sbjct: 665 HQRLTAALVLRHPW 678 Score = 63.9 bits (154), Expect = 3e-10 Identities = 37/112 (33%), Positives = 68/112 (60%), Gaps = 1/112 (0%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTV-GTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGS 202 +K+ DFG SK ++ H K + GT Y+APEV++R+ + + AD WS GV ++ ML G+ Sbjct: 207 IKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNRRGHT-QSADWWSFGVLMFEMLTGT 265 Query: 203 YPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRI 358 PF+ ++ ++T++ IL + +P + +S + + LL +F +P+ R+ Sbjct: 266 LPFQG----KDRKETMTMILKAKLGMPQF--LSPEAQSLLRMLFKRNPANRL 311
>ST17A_RABIT (Q9GM70) Serine/threonine-protein kinase 17A (EC 2.7.11.1) (DAP| kinase-related apoptosis-inducing protein kinase 1) (rDRAK1) Length = 397 Score = 70.1 bits (170), Expect = 4e-12 Identities = 46/132 (34%), Positives = 63/132 (47%), Gaps = 2/132 (1%) Frame = +2 Query: 11 SPTPRVKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYD--GKVADVWSCGVTLY 184 SP +KI DFG S+ + + +GTP Y+APE+LS YD D+WS GV Y Sbjct: 181 SPLGDIKIVDFGLSRIVKNSEELREIMGTPEYVAPEILS---YDPISMATDMWSIGVLTY 237 Query: 185 VMLIGSYPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITI 364 VML G PF F IS+ + + YS ++ VS + ++ P R T Sbjct: 238 VMLTGISPFLGDNKQETF-LNISQ-MNLSYSEEEFDTVSESAVDFIKKLLVKKPEDRATA 295 Query: 365 AEIKKLPWYLKS 400 E K PW +S Sbjct: 296 EECLKHPWLTQS 307
>KKCC1_RAT (P97756) Calcium/calmodulin-dependent protein kinase kinase 1 (EC| 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase alpha) (CaM-kinase kinase alpha) (CaM-KK alpha) (CaMKK alpha) (alpha CaMKK) (CaMKK 1) (CaM-kinase IV kinase) Length = 505 Score = 70.1 bits (170), Expect = 4e-12 Identities = 45/127 (35%), Positives = 65/127 (51%), Gaps = 3/127 (2%) Frame = +2 Query: 26 VKICDFGYSKSALLH-SKPKPTVGTPAYIAPEVLSR--KEYDGKVADVWSCGVTLYVMLI 196 VKI DFG S + ++ T GTPA++APE +S + + GK DVW+ GVTLY + Sbjct: 289 VKIADFGVSNQFEGNDAQLSSTAGTPAFMAPEAISDTGQSFSGKALDVWATGVTLYCFVY 348 Query: 197 GSYPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIK 376 G PF D RK I P+ VS + + L+ ++ +P RI +++IK Sbjct: 349 GKCPFIDEYILALHRK----IKNEAVVFPEEPEVSEELKDLILKMLDKNPETRIGVSDIK 404 Query: 377 KLPWYLK 397 PW K Sbjct: 405 LHPWVTK 411
>CDPK1_PLAYO (Q7RAH3) Calcium-dependent protein kinase 1 (EC 2.7.11.1)| Length = 534 Score = 70.1 bits (170), Expect = 4e-12 Identities = 44/124 (35%), Positives = 62/124 (50%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSY 205 +KI DFG S K + +GT YIAPEVL +K+Y+ K DVWSCGV +Y++L G Sbjct: 206 IKIVDFGLSSFFSKDYKLRDRLGTAYYIAPEVL-KKKYNEK-CDVWSCGVIMYILLCGYP 263 Query: 206 PFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLP 385 PF D +K + D+ +S + + L+ + T D +KR T E Sbjct: 264 PFGGQNDQDIIKKVEKG--KYYFDFNDWKNISDEAKELIKLMLTYDYNKRCTAEEALNSR 321 Query: 386 WYLK 397 W K Sbjct: 322 WIKK 325
>KPSH1_PINFU (Q4KTY1) Serine/threonine-protein kinase H1 homolog (EC 2.7.11.1)| Length = 415 Score = 70.1 bits (170), Expect = 4e-12 Identities = 50/168 (29%), Positives = 84/168 (50%), Gaps = 17/168 (10%) Frame = +2 Query: 23 RVKICDFGYSKSAL-LHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIG 199 ++ I DFG S + + + T GTP YIAPE+++RK Y +V D+W+ GV Y++L G Sbjct: 214 KIMITDFGLSSTRKGPENFMRTTCGTPEYIAPEIIARKPYMCQV-DMWAVGVITYILLSG 272 Query: 200 SYPFEDPEDPRNFRKTISRILGVQYSI--PDYVRVSSDCRRLLSQIFTADPSKRITIAEI 373 + PF+D R +R IL +YS + VS+ + + ++ P R++ A+ Sbjct: 273 TMPFDDENKTRLYR----LILKAKYSYAGEHWKDVSAQAKDFIDKLLVVSPGDRLSAADA 328 Query: 374 KKLPWYL--------KSLPKEIAER------DRANFKEPEKATETAAS 475 K W + K+L + I++ RAN + K+T + S Sbjct: 329 LKHQWLISNAASSSNKNLHRTISQNLIHRQSTRANSTKSAKSTRSTKS 376
>KIN4_YEAST (Q01919) Serine/threonine-protein kinase KIN4 (EC 2.7.11.1)| Length = 800 Score = 70.1 bits (170), Expect = 4e-12 Identities = 45/124 (36%), Positives = 66/124 (53%), Gaps = 5/124 (4%) Frame = +2 Query: 32 ICDFGYSKSALLHSK-PKPTVGTPAYIAPE-VLSRKEYDGKVADVWSCGVTLYVMLIGSY 205 I DFG+ ++ K + G+P Y APE V+S K Y+ + ADVWSCGV LY ML G Sbjct: 191 ITDFGFVNEFFEDNELMKTSCGSPCYAAPELVVSTKAYEARKADVWSCGVILYAMLAGYL 250 Query: 206 PFEDP-EDPR--NFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIK 376 P++D E+P + + I P+Y ++ R LL +I +P +RI + IK Sbjct: 251 PWDDDHENPTGDDIARLYKYITQTPLKFPEY--ITPIPRDLLRRILVPNPRRRINLQTIK 308 Query: 377 KLPW 388 + W Sbjct: 309 RHVW 312
>CDR1_SCHPO (P07334) Mitosis inducer protein kinase cdr1 (EC 2.7.11.1) (Protein| kinase nim1) Length = 593 Score = 70.1 bits (170), Expect = 4e-12 Identities = 44/124 (35%), Positives = 65/124 (52%) Frame = +2 Query: 23 RVKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGS 202 ++KI DFG + S + G+ Y+APE++S K Y G ADVWSCGV LY +L Sbjct: 142 QIKIADFGMATVEPNDSCLENYCGSLHYLAPEIVSHKPYRGAPADVWSCGVILYSLLSNK 201 Query: 203 YPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKL 382 PF +N ++I Y +P +SS + LL ++ +PS RITI E+ Sbjct: 202 LPF----GGQNTDVIYNKIRHGAYDLPS--SISSAAQDLLHRMLDVNPSTRITIPEVFSH 255 Query: 383 PWYL 394 P+ + Sbjct: 256 PFLM 259
>TRIB3_RAT (Q9WTQ6) Tribbles homolog 3 (TRB-3) (Neuronal cell death-inducible| putative kinase) Length = 349 Score = 69.7 bits (169), Expect = 5e-12 Identities = 39/98 (39%), Positives = 55/98 (56%), Gaps = 1/98 (1%) Frame = +2 Query: 98 PAYIAPEVLS-RKEYDGKVADVWSCGVTLYVMLIGSYPFEDPEDPRNFRKTISRILGVQY 274 PAY+ PE+LS R Y G+ ADVWS GV L+ ML G YPF+D E F K I + Sbjct: 218 PAYVGPEILSSRPSYSGRAADVWSLGVALFTMLAGRYPFQDSEPALLFGK----IRRGTF 273 Query: 275 SIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLPW 388 ++P+ + S+ C L+ + +PS+R+ I PW Sbjct: 274 ALPEGLSASARC--LIRCLLRREPSERLVALGILLHPW 309
>ATG1_MAGGR (Q52EB3) Serine/threonine-protein kinase ATG1 (EC 2.7.11.1)| (Autophagy-related protein 1) Length = 982 Score = 69.7 bits (169), Expect = 5e-12 Identities = 43/161 (26%), Positives = 78/161 (48%), Gaps = 4/161 (2%) Frame = +2 Query: 20 PRVKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIG 199 P +K+ DFG+++ S + G+P Y+APE+L + YD K AD+WS G L+ M++G Sbjct: 204 PMLKLADFGFARVLPSTSLAETLCGSPLYMAPEILRYERYDAK-ADLWSVGTVLFEMIVG 262 Query: 200 SYPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKK 379 PF RK + +++ P +SS+ + L + +P +RI+ Sbjct: 263 RPPFRASNHVELLRKIEAAEDVIKF--PRETTISSEMKGLTRALLKRNPVERISFENFFA 320 Query: 380 LPWYLKSLP----KEIAERDRANFKEPEKATETAASAAQPV 490 P + S+P +I + + + + K T A+ + P+ Sbjct: 321 HPVIISSIPGLVEDDIPKPEASEQRSSSKDTRAASKSDDPI 361
>KK31_SCHPO (Q9HFF4) Probable serine/threonine-protein kinase C110.01 (EC| 2.7.11.1) Length = 1023 Score = 69.3 bits (168), Expect = 6e-12 Identities = 45/123 (36%), Positives = 65/123 (52%), Gaps = 12/123 (9%) Frame = +2 Query: 41 FGYSKSALLHSKP--KPTV-----GTPAYIAPEVLSRKE--YDGKVADVWSCGVTLYVML 193 FG+ + HS P KP + G+P Y APE+++ K Y G AD+WSCGV LY ML Sbjct: 648 FGHFNTLSEHSLPTEKPDLFSTSCGSPCYAAPELVNCKSGMYAGTQADIWSCGVILYAML 707 Query: 194 IGSYPF-EDPEDP--RNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITI 364 G PF +DP +P N + I P++ + S R +L +I DP+KR+ + Sbjct: 708 AGYLPFDDDPHNPNGENVPRLYRYICSTPLIFPEFFK--SKARDILKKILVPDPAKRVRM 765 Query: 365 AEI 373 + I Sbjct: 766 SAI 768
>KPCD_HUMAN (Q05655) Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta)| Length = 676 Score = 69.3 bits (168), Expect = 6e-12 Identities = 44/137 (32%), Positives = 70/137 (51%), Gaps = 2/137 (1%) Frame = +2 Query: 26 VKICDFGYSKSALL-HSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGS 202 +KI DFG K + S+ GTP YIAPE+L +Y V D WS GV LY MLIG Sbjct: 487 IKIADFGMCKENIFGESRASTFCGTPDYIAPEILQGLKYTFSV-DWWSFGVLLYEMLIGQ 545 Query: 203 YPFEDPEDPRNFRKTISRILGVQYSIPDYVR-VSSDCRRLLSQIFTADPSKRITIAEIKK 379 PF ++ F ++ P Y R ++ + + +L ++F +P+KR+ + K Sbjct: 546 SPFHGDDEDELFE-------SIRVDTPHYPRWITKESKDILEKLFEREPTKRLGMTGNIK 598 Query: 380 LPWYLKSLPKEIAERDR 430 + + K++ + E+ R Sbjct: 599 IHPFFKTINWTLLEKRR 615
>PLK3_RAT (Q9R011) Serine/threonine-protein kinase PLK3 (EC 2.7.11.21)| (Polo-like kinase 3) (PLK-3) (Cytokine-inducible serine/threonine-protein kinase) (FGF-inducible kinase) (Fragment) Length = 615 Score = 69.3 bits (168), Expect = 6e-12 Identities = 46/125 (36%), Positives = 69/125 (55%), Gaps = 1/125 (0%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTV-GTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGS 202 +K+ DFG + + K T+ GTP Y+APEVL R+ + G ADVWS G +Y +L GS Sbjct: 168 LKVGDFGLAARLEPPEQRKKTICGTPNYVAPEVLLRQGH-GPEADVWSLGCVMYTLLCGS 226 Query: 203 YPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKL 382 PFE + ++T I V Y++P +S R+LL+ I A P R +I +I + Sbjct: 227 PPFETAD----LKETYRCIKQVHYTLP--ASLSLPARQLLAAILRASPRDRPSIEQILRH 280 Query: 383 PWYLK 397 ++ K Sbjct: 281 DFFTK 285
>KS6AA_XENLA (P10665) Ribosomal protein S6 kinase 2 alpha (EC 2.7.11.1)| (Ribosomal protein S6 kinase II alpha) (S6KII-alpha) (P90-RSK) (MAP kinase-activated protein kinase 1) (MAPK-activated protein kinase 1) (MAPKAP kinase 1) (MAPKAPK-1) Length = 733 Score = 69.3 bits (168), Expect = 6e-12 Identities = 44/128 (34%), Positives = 76/128 (59%), Gaps = 6/128 (4%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTV-GTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGS 202 +K+ DFG SK A+ H K + GT Y+APEV++R+ + AD WS GV ++ ML GS Sbjct: 201 IKLTDFGLSKEAIDHEKKAYSFCGTVEYMAPEVVNRQGHSHS-ADWWSYGVLMFEMLTGS 259 Query: 203 YPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIA----- 367 PF+ ++ ++T++ IL + +P + +S++ + LL +F +P+ R+ A Sbjct: 260 LPFQG----KDRKETMTLILKAKLGMPQF--LSNEAQSLLRALFKRNPTNRLGSAMEGAE 313 Query: 368 EIKKLPWY 391 EIK+ P++ Sbjct: 314 EIKRQPFF 321 Score = 68.2 bits (165), Expect = 1e-11 Identities = 53/174 (30%), Positives = 94/174 (54%), Gaps = 12/174 (6%) Frame = +2 Query: 2 LDGSPTPR-VKICDFGYSKSALLHSKPKPT-VGTPAYIAPEVLSRKEYDGKVADVWSCGV 175 +D S P ++ICDFG++K + T T ++APEVL R+ YD + D+WS G+ Sbjct: 542 VDESGDPESIRICDFGFAKQLRADNGLLMTPCYTANFVAPEVLKRQGYD-EGCDIWSLGI 600 Query: 176 TLYVMLIGSYPF-----EDPEDPRNFRKTISRILGVQYSI--PDYVRVSSDCRRLLSQIF 334 LY ML G PF + PE+ ++RI ++++ ++ VS+ + L+S++ Sbjct: 601 LLYTMLAGYTPFANGLGDTPEE------ILARIGSGKFTLRGGNWNTVSAAAKDLVSRML 654 Query: 335 TADPSKRITIAEIKKLPWYLK--SLPK-EIAERDRANFKEPEKATETAASAAQP 487 DP KR+T ++ + W K +LP+ ++ +D K AT +A ++++P Sbjct: 655 HVDPHKRLTAKQVLQHEWITKRDALPQSQLNRQDVHLVKGAMAATYSALNSSKP 708
>PLK3_MOUSE (Q60806) Serine/threonine-protein kinase PLK3 (EC 2.7.11.21)| (Polo-like kinase 3) (PLK-3) (Cytokine-inducible serine/threonine-protein kinase) (FGF-inducible kinase) Length = 631 Score = 69.3 bits (168), Expect = 6e-12 Identities = 46/125 (36%), Positives = 69/125 (55%), Gaps = 1/125 (0%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTV-GTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGS 202 +K+ DFG + + K T+ GTP Y+APEVL R+ + G ADVWS G +Y +L GS Sbjct: 200 LKVGDFGLAARLEPPEQRKKTICGTPNYVAPEVLLRQGH-GPEADVWSLGCVMYTLLCGS 258 Query: 203 YPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKL 382 PFE + ++T I V Y++P +S R+LL+ I A P R +I +I + Sbjct: 259 PPFETAD----LKETYRCIKQVHYTLP--ASLSLPARQLLAAILRASPRDRPSIEQILRH 312 Query: 383 PWYLK 397 ++ K Sbjct: 313 DFFTK 317
>ATG1_DEBHA (Q6BS08) Serine/threonine-protein kinase ATG1 (EC 2.7.11.1)| (Autophagy-related protein 1) Length = 875 Score = 69.3 bits (168), Expect = 6e-12 Identities = 45/148 (30%), Positives = 71/148 (47%), Gaps = 8/148 (5%) Frame = +2 Query: 20 PRVKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIG 199 P +KI DFG+++ S + G+P Y+APE+L ++Y+ K AD+WS G LY M +G Sbjct: 198 PLLKIADFGFARFLPSTSMAETLCGSPLYMAPEILRYEKYNAK-ADLWSVGAVLYEMTVG 256 Query: 200 SYPFEDPEDP---RNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAE 370 PF +N K+ RI P +V +RL+ + +P++R++ E Sbjct: 257 KPPFRADNHVQLLKNIEKSNDRI-----KFPSAAQVPESLKRLIRSLLKYNPTERVSFNE 311 Query: 371 IKKLPWYLKSL-----PKEIAERDRANF 439 P + L P E +E D F Sbjct: 312 FFNDPLIVNDLEGNDEPLETSEMDENLF 339
>PLK3_HUMAN (Q9H4B4) Serine/threonine-protein kinase PLK3 (EC 2.7.11.21)| (Polo-like kinase 3) (PLK-3) (Cytokine-inducible serine/threonine-protein kinase) (FGF-inducible kinase) (Proliferation-related kinase) Length = 646 Score = 68.9 bits (167), Expect = 8e-12 Identities = 46/125 (36%), Positives = 69/125 (55%), Gaps = 1/125 (0%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTV-GTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGS 202 +K+ DFG + + K T+ GTP Y+APEVL R+ + G ADVWS G +Y +L GS Sbjct: 199 LKVGDFGLAARLEPPEQRKKTICGTPNYVAPEVLLRQGH-GPEADVWSLGCVMYTLLCGS 257 Query: 203 YPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKL 382 PFE + ++T I V Y++P +S R+LL+ I A P R +I +I + Sbjct: 258 PPFETAD----LKETYRCIKQVHYTLP--ASLSLPARQLLAAILRASPRDRPSIDQILRH 311 Query: 383 PWYLK 397 ++ K Sbjct: 312 DFFTK 316
>KPCD_RAT (P09215) Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta)| Length = 673 Score = 68.9 bits (167), Expect = 8e-12 Identities = 43/135 (31%), Positives = 68/135 (50%), Gaps = 2/135 (1%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTV-GTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGS 202 +KI DFG K + T GTP YIAPE+L +Y V D WS GV LY MLIG Sbjct: 485 IKIADFGMCKENIFGENRASTFCGTPDYIAPEILQGLKYSFSV-DWWSFGVLLYEMLIGQ 543 Query: 203 YPFEDPEDPRNFRKTISRILGVQYSIPDYVR-VSSDCRRLLSQIFTADPSKRITIAEIKK 379 PF ++ F ++ P Y R ++ + + ++ ++F DP+KR+ + + Sbjct: 544 SPFHGDDEDELFE-------SIRVDTPHYPRWITKESKDIMEKLFERDPAKRLGVTGNIR 596 Query: 380 LPWYLKSLPKEIAER 424 L + K++ + E+ Sbjct: 597 LHPFFKTINWNLLEK 611
>ATG1_SCHPO (Q9Y7T4) Serine/threonine-protein kinase atg1 (EC 2.7.11.1)| (Autophagy-related protein 1) Length = 830 Score = 68.9 bits (167), Expect = 8e-12 Identities = 40/118 (33%), Positives = 63/118 (53%), Gaps = 1/118 (0%) Frame = +2 Query: 8 GSPT-PRVKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLY 184 GSP P +K+ DFG+++ S + G+P Y+APE+L ++YD K AD+WS G LY Sbjct: 182 GSPKLPMLKLADFGFARYLQTSSMAETLCGSPLYMAPEILRYEKYDAK-ADLWSVGAVLY 240 Query: 185 VMLIGSYPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRI 358 M +G PF+ P R+ I + V P+ + D + L+ + +P+ RI Sbjct: 241 EMAVGKPPFKAPNHVELLRR-IQKAKDV-IKFPEEAFIHPDIKTLICALLKQNPADRI 296
>DAPK3_HUMAN (O43293) Death-associated protein kinase 3 (EC 2.7.11.1) (DAP| kinase 3) (DAP-like kinase) (Dlk) (ZIP-kinase) Length = 454 Score = 68.9 bits (167), Expect = 8e-12 Identities = 41/149 (27%), Positives = 75/149 (50%), Gaps = 2/149 (1%) Frame = +2 Query: 14 PTPRVKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVML 193 P PR+K+ DFG + ++ K GTP ++APE+++ + G AD+WS GV Y++L Sbjct: 153 PNPRIKLIDFGIAHKIEAGNEFKNIFGTPEFVAPEIVNYEPL-GLEADMWSIGVITYILL 211 Query: 194 IGSYPFEDPEDPRNFRKTISRILGVQYSIPD--YVRVSSDCRRLLSQIFTADPSKRITIA 367 G+ PF ++T++ I V Y + + S + + ++ DP +R+TIA Sbjct: 212 SGASPFLG----ETKQETLTNISAVNYDFDEEYFSNTSELAKDFIRRLLVKDPKRRMTIA 267 Query: 368 EIKKLPWYLKSLPKEIAERDRANFKEPEK 454 + + W + + D ++PE+ Sbjct: 268 QSLEHSWIKAIRRRNVRGEDSG--RKPER 294
>ATG1_YEAST (P53104) Serine/threonine-protein kinase ATG1 (EC 2.7.11.1)| (Autophagy-related protein 1) (Autophagy protein 3) (Cytoplasm to vacuole targeting protein 10) Length = 897 Score = 68.6 bits (166), Expect = 1e-11 Identities = 39/117 (33%), Positives = 64/117 (54%) Frame = +2 Query: 20 PRVKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIG 199 P +KI DFG+++ S + G+P Y+APE+L+ ++Y+ K AD+WS G ++ M G Sbjct: 205 PILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAK-ADLWSVGTVVFEMCCG 263 Query: 200 SYPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAE 370 + PF F+K I R V + P Y + + + L+ + T DP++RI E Sbjct: 264 TPPFRASNHLELFKK-IKRANDV-ITFPSYCNIEPELKELICSLLTFDPAQRIGFEE 318
>PLK1_XENLA (P70032) Serine/threonine-protein kinase PLK1 (EC 2.7.11.21)| (Polo-like kinase 1) (PLK-1) (Plx1) Length = 598 Score = 68.6 bits (166), Expect = 1e-11 Identities = 43/117 (36%), Positives = 66/117 (56%), Gaps = 1/117 (0%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTV-GTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGS 202 VKI DFG + + K T+ GTP YIAPEVL +K + +V D+WS G +Y +L+G Sbjct: 181 VKIGDFGLATKVEYDGERKKTLCGTPNYIAPEVLGKKGHSFEV-DIWSIGCIMYTLLVGK 239 Query: 203 YPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEI 373 PFE ++T RI +YSIP + ++ L+ ++ +DP+ R TI ++ Sbjct: 240 PPFE----TSCLKETYMRIKKNEYSIPKH--INPVAAALIQKMLRSDPTSRPTIDDL 290
>CSKP_HUMAN (O14936) Peripheral plasma membrane protein CASK (EC 2.7.11.1)| (hCASK) (Calcium/calmodulin-dependent serine protein kinase) (Lin-2 homolog) Length = 926 Score = 68.6 bits (166), Expect = 1e-11 Identities = 40/120 (33%), Positives = 64/120 (53%), Gaps = 2/120 (1%) Frame = +2 Query: 89 VGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSYPFEDPEDPRNFRKTISRILGV 268 VGTP ++APEV+ R+ Y GK DVW CGV L+++L G PF ++ + I+ Sbjct: 180 VGTPHFMAPEVVKREPY-GKPVDVWGCGVILFILLSGCLPFYGTKE-----RLFEGIIKG 233 Query: 269 QYSI--PDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLPWYLKSLPKEIAERDRANFK 442 +Y + + +S + L+ ++ DP++RIT+ E PW + ERDR +K Sbjct: 234 KYKMNPRQWSHISESAKDLVRRMLMLDPAERITVYEALNHPW--------LKERDRYAYK 285
>CSKP_RAT (Q62915) Peripheral plasma membrane protein CASK (EC 2.7.11.1)| (Calcium/calmodulin-dependent serine protein kinase) Length = 909 Score = 68.6 bits (166), Expect = 1e-11 Identities = 40/120 (33%), Positives = 64/120 (53%), Gaps = 2/120 (1%) Frame = +2 Query: 89 VGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSYPFEDPEDPRNFRKTISRILGV 268 VGTP ++APEV+ R+ Y GK DVW CGV L+++L G PF ++ + I+ Sbjct: 180 VGTPHFMAPEVVKREPY-GKPVDVWGCGVILFILLSGCLPFYGTKE-----RLFEGIIKG 233 Query: 269 QYSI--PDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLPWYLKSLPKEIAERDRANFK 442 +Y + + +S + L+ ++ DP++RIT+ E PW + ERDR +K Sbjct: 234 KYKMNPRQWSHISESAKDLVRRMLMLDPAERITVYEALNHPW--------LKERDRYAYK 285
>CSKP_MOUSE (O70589) Peripheral plasma membrane protein CASK (EC 2.7.11.1)| (Calcium/calmodulin-dependent serine protein kinase) Length = 924 Score = 68.6 bits (166), Expect = 1e-11 Identities = 40/120 (33%), Positives = 64/120 (53%), Gaps = 2/120 (1%) Frame = +2 Query: 89 VGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSYPFEDPEDPRNFRKTISRILGV 268 VGTP ++APEV+ R+ Y GK DVW CGV L+++L G PF ++ + I+ Sbjct: 180 VGTPHFMAPEVVKREPY-GKPVDVWGCGVILFILLSGCLPFYGTKE-----RLFEGIIKG 233 Query: 269 QYSI--PDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLPWYLKSLPKEIAERDRANFK 442 +Y + + +S + L+ ++ DP++RIT+ E PW + ERDR +K Sbjct: 234 KYKMNPRQWSHISESAKDLVRRMLMLDPAERITVYEALNHPW--------LKERDRYAYK 285
>AURKC_MOUSE (O88445) Serine/threonine-protein kinase 13 (EC 2.7.11.1)| (Aurora/Ipl1/Eg2 protein 1) (Aurora-C) Length = 282 Score = 68.6 bits (166), Expect = 1e-11 Identities = 41/124 (33%), Positives = 69/124 (55%), Gaps = 3/124 (2%) Frame = +2 Query: 26 VKICDFGYSKSALLHS---KPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLI 196 VKI DFG+S +H+ + K GT Y+ PE++++K Y+ ++ D+W GV Y +L+ Sbjct: 153 VKISDFGWS----VHTPSLRRKTMCGTLDYLPPEMIAQKPYN-EMVDLWCIGVLCYELLV 207 Query: 197 GSYPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIK 376 G PFE +R RI V + P V + + L+S++ PS+R+++A++ Sbjct: 208 GKPPFESSTSSETYR----RIRQVDFKFPS--SVPAGAQDLISKLLRYHPSERLSLAQVL 261 Query: 377 KLPW 388 K PW Sbjct: 262 KHPW 265
>LOK_DROME (O61267) Ovarian-specific serine/threonine-protein kinase Lok (EC| 2.7.11.1) (Protein loki) (dMNK) Length = 476 Score = 68.6 bits (166), Expect = 1e-11 Identities = 50/154 (32%), Positives = 73/154 (47%), Gaps = 13/154 (8%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTVGTPAYIAPEVL---SRKEYDGKVADVWSCGVTLYVMLI 196 +K+ DFG SK S + GTP Y+APEVL R+ Y KV D+WS GV L+ L Sbjct: 320 LKVSDFGLSKFVQKDSVMRTLCGTPLYVAPEVLITGGREAYTKKV-DIWSLGVVLFTCLS 378 Query: 197 GSYPFEDP-EDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEI 373 G+ PF D P + R Y P + VS + L++Q+ DP +R +I ++ Sbjct: 379 GTLPFSDEYGTPAAQQIKKGRF---AYGHPSWKSVSQRAKLLINQMLIVDPERRPSIDDV 435 Query: 374 KKLPWYLKSLPKEIAER---------DRANFKEP 448 + W + + A+R + NF EP Sbjct: 436 LQSSWLRDAPMLQKAKRLMKLDGMEIEEENFLEP 469
>PHKG1_RABIT (P00518) Phosphorylase b kinase gamma catalytic chain, skeletal| muscle isoform (EC 2.7.11.19) (Phosphorylase kinase gamma subunit 1) Length = 386 Score = 68.6 bits (166), Expect = 1e-11 Identities = 44/145 (30%), Positives = 69/145 (47%), Gaps = 6/145 (4%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYD-----GKVADVWSCGVTLYVM 190 +K+ DFG+S K + GTP+Y+APE++ D GK D+WS GV +Y + Sbjct: 163 IKLTDFGFSCQLDPGEKLREVCGTPSYLAPEIIECSMNDNHPGYGKEVDMWSTGVIMYTL 222 Query: 191 LIGSYPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAE 370 L GS PF + R +S Q+ P++ S + L+S+ P KR T E Sbjct: 223 LAGSPPFWHRKQMLMLRMIMSG--NYQFGSPEWDDYSDTVKDLVSRFLVVQPQKRYTAEE 280 Query: 371 IKKLPWYLKSLPKEIAE-RDRANFK 442 P++ + + +E+ R FK Sbjct: 281 ALAHPFFQQYVVEEVRHFSPRGKFK 305
>OBSCN_HUMAN (Q5VST9) Obscurin (Obscurin-myosin light chain kinase)| (Obscurin-MLCK) (Obscurin-RhoGEF) Length = 7968 Score = 68.6 bits (166), Expect = 1e-11 Identities = 39/133 (29%), Positives = 66/133 (49%), Gaps = 2/133 (1%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSY 205 +KICDFG++++ G+P +++PE++ + + +D+W+ GV Y+ L S Sbjct: 6603 IKICDFGFAQNITPAELQFSQYGSPEFVSPEIIQQNPVS-EASDIWAMGVISYLSLTCSS 6661 Query: 206 PFEDPEDPRNFRKTISRILG--VQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKK 379 PF D R T+ +L V +S P +S D + + P R + A+ Sbjct: 6662 PFAGESD----RATLLNVLEGRVSWSSPMAAHLSEDAKDFIKATLQRAPQARPSAAQCLS 6717 Query: 380 LPWYLKSLPKEIA 418 PW+LKS+P E A Sbjct: 6718 HPWFLKSMPAEEA 6730 Score = 37.4 bits (85), Expect = 0.025 Identities = 36/132 (27%), Positives = 57/132 (43%), Gaps = 5/132 (3%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTVGTPAYI---APEVLSRKEYDGKV--ADVWSCGVTLYVM 190 +K+ D G ++S L K P+ Y+ APE+L E G V D+W+ GVT ++M Sbjct: 7805 LKVVDLGNAQS-LSQEKVLPSDKFKDYLETMAPELL---EGQGAVPQTDIWAIGVTAFIM 7860 Query: 191 LIGSYPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAE 370 L YP E R+ ++ + + G+ Y +S L A P R + Sbjct: 7861 LSAEYPVSS-EGARDLQRGLRK--GLVRLSRCYAGLSGGAVAFLRSTLCAQPWGRPCASS 7917 Query: 371 IKKLPWYLKSLP 406 + PW + P Sbjct: 7918 CLQCPWLTEEGP 7929
>HAL5_YEAST (P38970) Serine/threonine-protein kinase HAL5 (EC 2.7.11.1)| (Halotolerence protein 5) Length = 855 Score = 68.6 bits (166), Expect = 1e-11 Identities = 49/144 (34%), Positives = 72/144 (50%), Gaps = 15/144 (10%) Frame = +2 Query: 14 PTPRVKICDFGYSK------SALLHSKPKPTVGTPAYIAPEVLSRK-EYDGKVADVWSCG 172 P +KICDFG S +H + +G+ Y+APE R EYD ++ D WSCG Sbjct: 698 PNGLLKICDFGTSSVFQTAWEKHVHFQ-SGAMGSEPYVAPEEFIRDAEYDPRLVDCWSCG 756 Query: 173 VTLYVMLIGSYPFE--DPEDPRNFRKTISRIL--GVQYSIPDYVRVSSDCRRL----LSQ 328 + M++G Y ++ PE F+ +S I G Y + VSS+ RL L + Sbjct: 757 IVYCTMVMGQYLWKIAIPEKDSLFKSFLSEIKDDGQFYLFEELRHVSSELNRLRKIALYR 816 Query: 329 IFTADPSKRITIAEIKKLPWYLKS 400 F DP+KRITI ++ + W K+ Sbjct: 817 TFQVDPTKRITIEQLLQSSWMRKT 840
>POLO_DROME (P52304) Serine/threonine-protein kinase polo (EC 2.7.11.21)| Length = 576 Score = 68.6 bits (166), Expect = 1e-11 Identities = 46/146 (31%), Positives = 74/146 (50%), Gaps = 9/146 (6%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTV-GTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGS 202 VKI DFG + + K T+ GTP YIAPE+L++K + +V D+WS G +Y +L+G Sbjct: 162 VKIGDFGLATRIEYEGERKKTLCGTPNYIAPEILTKKGHSFEV-DIWSIGCVMYTLLVGQ 220 Query: 203 YPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEI--- 373 PFE + + T S+I +Y +P Y+R ++ + +P R I ++ Sbjct: 221 PPFE----TKTLKDTYSKIKKCEYRVPSYLR--KPAADMVIAMLQPNPESRPAIGQLLNF 274 Query: 374 -----KKLPWYLKSLPKEIAERDRAN 436 K+P +L S +A R +N Sbjct: 275 EFLKGSKVPMFLPSSCLTMAPRIGSN 300
>ST17A_HUMAN (Q9UEE5) Serine/threonine-protein kinase 17A (EC 2.7.11.1) (DAP| kinase-related apoptosis-inducing protein kinase 1) Length = 414 Score = 68.6 bits (166), Expect = 1e-11 Identities = 51/164 (31%), Positives = 73/164 (44%), Gaps = 2/164 (1%) Frame = +2 Query: 11 SPTPRVKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYD--GKVADVWSCGVTLY 184 SP +KI DFG S+ + + +GTP Y+APE+LS YD D+WS GV Y Sbjct: 198 SPLGDIKIVDFGLSRILKNSEELREIMGTPEYVAPEILS---YDPISMATDMWSIGVLTY 254 Query: 185 VMLIGSYPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITI 364 VML G PF + F IS+ + + YS ++ +S + + P R T Sbjct: 255 VMLTGISPFLGNDKQETF-LNISQ-MNLSYSEEEFDVLSESAVDFIRTLLVKKPEDRATA 312 Query: 365 AEIKKLPWYLKSLPKEIAERDRANFKEPEKATETAASAAQPVEE 496 E K PW +S + +EP E A A ++E Sbjct: 313 EECLKHPWLTQS-----------SIQEPSFRMEKALEEANALQE 345
>CCAMK_LILLO (Q43531) Calcium and calcium/calmodulin-dependent| serine/threonine-protein kinase (EC 2.7.11.17) (LlCCaMK) Length = 520 Score = 68.6 bits (166), Expect = 1e-11 Identities = 41/131 (31%), Positives = 67/131 (51%), Gaps = 2/131 (1%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSY 205 +KI DFG S G+ Y++PE LS+++ +D+WS GV LY++L G Sbjct: 184 LKIMDFGLSSVEDFTDPIVALFGSIDYVSPEALSQRQVSS-ASDMWSLGVILYILLSGCP 242 Query: 206 PFEDPEDPRNFRKTISRILGVQYSIPDYV--RVSSDCRRLLSQIFTADPSKRITIAEIKK 379 PF P + R+ RIL +S ++ ++S + L+S + + DP KR T ++ K Sbjct: 243 PFHAPSN----REKQQRILAGDFSFEEHTWKTITSSAKDLISSLLSVDPYKRPTANDLLK 298 Query: 380 LPWYLKSLPKE 412 PW + K+ Sbjct: 299 HPWVIGDSAKQ 309
>TRIB3_MOUSE (Q8K4K2) Tribbles homolog 3 (TRB-3) (Neuronal cell death-inducible| putative kinase) Length = 354 Score = 68.2 bits (165), Expect = 1e-11 Identities = 40/98 (40%), Positives = 54/98 (55%), Gaps = 1/98 (1%) Frame = +2 Query: 98 PAYIAPEVLS-RKEYDGKVADVWSCGVTLYVMLIGSYPFEDPEDPRNFRKTISRILGVQY 274 PAY+ PE+LS R Y GK ADVWS GV L+ ML G YPF D E F K I + Sbjct: 223 PAYVGPEILSSRPSYSGKAADVWSLGVALFTMLAGRYPFHDSEPVLLFGK----IRRGTF 278 Query: 275 SIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLPW 388 ++P+ +S+ R L+ + +PS+R+ I PW Sbjct: 279 ALPE--GLSAPARCLIRCLLRKEPSERLVALGILLHPW 314
>KPCT_HUMAN (Q04759) Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta)| Length = 706 Score = 68.2 bits (165), Expect = 1e-11 Identities = 45/137 (32%), Positives = 73/137 (53%), Gaps = 3/137 (2%) Frame = +2 Query: 26 VKICDFGYSKSALL-HSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGS 202 +KI DFG K +L +K GTP YIAPE+L ++Y+ V D WS GV LY MLIG Sbjct: 518 IKIADFGMCKENMLGDAKTNTFCGTPDYIAPEILLGQKYNHSV-DWWSFGVLLYEMLIGQ 576 Query: 203 YPFEDPEDPRNFRKTISRILGVQYSIPDYVR-VSSDCRRLLSQIFTADPSKRITI-AEIK 376 PF ++ F ++ P Y R + + + LL ++F +P KR+ + +I+ Sbjct: 577 SPFHGQDEEELFH-------SIRMDNPFYPRWLEKEAKDLLVKLFVREPEKRLGVRGDIR 629 Query: 377 KLPWYLKSLPKEIAERD 427 + P + + +E+ ++ Sbjct: 630 QHPLFREINWEELERKE 646
>ATG1_BOTCI (Q6H9I1) Serine/threonine-protein kinase ATG1 (EC 2.7.11.1)| (Autophagy-related protein 1) (Botryotinia fuckeliana putative kinase exons 1-3) Length = 952 Score = 68.2 bits (165), Expect = 1e-11 Identities = 43/144 (29%), Positives = 72/144 (50%) Frame = +2 Query: 20 PRVKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIG 199 P +K+ DFG+++S S + G+P Y+APE+L ++YD + AD+WS G LY M+ G Sbjct: 209 PMLKLADFGFARSLPSTSLAETLCGSPLYMAPEILRYEKYDAR-ADLWSIGTVLYEMMTG 267 Query: 200 SYPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKK 379 PF+ + +K +++ P S D + ++ ++ P RIT E Sbjct: 268 RPPFKAINHVQLLQKIEKNQDEIRF--PSRGIYSRDLKDIVRRLLKKKPEDRITFPEYFA 325 Query: 380 LPWYLKSLPKEIAERDRANFKEPE 451 P + +P + + DR K PE Sbjct: 326 HPVVTEPIPGLVGD-DRPKEKSPE 348
>STK6_XENLA (Q91820) Serine/threonine-protein kinase Eg2 (EC 2.7.11.1) (pEg2)| (p46Eg265) Length = 407 Score = 68.2 bits (165), Expect = 1e-11 Identities = 42/125 (33%), Positives = 67/125 (53%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSY 205 +KI DFG+S A S+ GT Y+ PE++ + +D V D+WS GV Y L+G Sbjct: 277 LKIADFGWSVHAP-SSRRTTLCGTLDYLPPEMIEGRMHDETV-DLWSLGVLCYEFLVGKP 334 Query: 206 PFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLP 385 PFE +R RI V++ P Y VS + R L+S++ +P+ R+ + + + P Sbjct: 335 PFETDTHQETYR----RISKVEFQYPPY--VSEEARDLVSKLLKHNPNHRLPLKGVLEHP 388 Query: 386 WYLKS 400 W +K+ Sbjct: 389 WIIKN 393
>NRKA_TRYBB (Q08942) Putative serine/threonine-protein kinase A (EC 2.7.11.1)| Length = 431 Score = 68.2 bits (165), Expect = 1e-11 Identities = 47/133 (35%), Positives = 73/133 (54%), Gaps = 4/133 (3%) Frame = +2 Query: 17 TPRVKICDFGYS---KSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYV 187 T VK+ DFG+S + + GTP Y+APE+ + K Y+ K ADVWS GV LY Sbjct: 158 TGLVKLGDFGFSHQYEDTVSGVVASTFCGTPYYLAPELWNNKRYNKK-ADVWSLGVLLYE 216 Query: 188 MLIGSYPFEDPEDPRNFRKTISRILGVQYS-IPDYVRVSSDCRRLLSQIFTADPSKRITI 364 ++ PF N + +S++L Y+ +PD SS+ +R++ I ADP+ R ++ Sbjct: 217 IMGMKKPF----SASNLKGLMSKVLAGTYAPLPD--SFSSEFKRVVDGILVADPNDRPSV 270 Query: 365 AEIKKLPWYLKSL 403 EI ++P+ K L Sbjct: 271 REIFQIPYINKGL 283
>MYLK_DICDI (P25323) Myosin light chain kinase (EC 2.7.11.18) (MLCK)| Length = 295 Score = 68.2 bits (165), Expect = 1e-11 Identities = 44/127 (34%), Positives = 62/127 (48%), Gaps = 2/127 (1%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSY 205 V I DFG SK + GTP+Y+APEVL+ YD K D+WS GV Y++L G Sbjct: 147 VAIADFGLSKIIGQTLVMQTACGTPSYVAPEVLNATGYD-KEVDMWSIGVITYILLCGFP 205 Query: 206 PFEDPEDPRNFRKTISRILGVQYSIPD--YVRVSSDCRRLLSQIFTADPSKRITIAEIKK 379 PF P F +I+ Y P+ + +S + + + ++ D SKR+ Sbjct: 206 PFYGDTVPEIF----EQIMEANYEFPEEYWGGISKEAKDFIGKLLVVDVSKRLNATNALN 261 Query: 380 LPWYLKS 400 PW LKS Sbjct: 262 HPW-LKS 267
>KAPC_YEAST (P05986) cAMP-dependent protein kinase type 3 (EC 2.7.11.11) (PKA| 3) Length = 398 Score = 68.2 bits (165), Expect = 1e-11 Identities = 47/138 (34%), Positives = 70/138 (50%), Gaps = 5/138 (3%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSY 205 +KI DFG++K + GTP YIAPEV+S K Y+ K D WS GV +Y ML G Sbjct: 225 IKITDFGFAK--YVPDVTYTLCGTPDYIAPEVVSTKPYN-KSVDWWSFGVLIYEMLAGYT 281 Query: 206 PFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRI-----TIAE 370 PF + N KT IL + P + D + LL ++ T D S+R+ + Sbjct: 282 PFYN----SNTMKTYENILNAELKFPPFFH--PDAQDLLKKLITRDLSERLGNLQNGSED 335 Query: 371 IKKLPWYLKSLPKEIAER 424 +K PW+ + + +++ R Sbjct: 336 VKNHPWFNEVIWEKLLAR 353
>PLK4_HUMAN (O00444) Serine/threonine-protein kinase PLK4 (EC 2.7.11.21)| (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase Sak) (Serine/threonine-protein kinase 18) Length = 970 Score = 67.8 bits (164), Expect = 2e-11 Identities = 37/122 (30%), Positives = 67/122 (54%), Gaps = 1/122 (0%) Frame = +2 Query: 26 VKICDFGYSKSALL-HSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGS 202 +KI DFG + + H K GTP YI+PE+ +R + G +DVWS G Y +LIG Sbjct: 150 IKIADFGLATQLKMPHEKHYTLCGTPNYISPEIATRSAH-GLESDVWSLGCMFYTLLIGR 208 Query: 203 YPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKL 382 PF D + T+++++ Y +P + +S + + L+ Q+ +P+ R++++ + Sbjct: 209 PPF----DTDTVKNTLNKVVLADYEMPTF--LSIEAKDLIHQLLRRNPADRLSLSSVLDH 262 Query: 383 PW 388 P+ Sbjct: 263 PF 264
>CHK2_MOUSE (Q9Z265) Serine/threonine-protein kinase Chk2 (EC 2.7.11.1)| Length = 546 Score = 67.8 bits (164), Expect = 2e-11 Identities = 49/163 (30%), Positives = 79/163 (48%), Gaps = 7/163 (4%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDG--KVADVWSCGVTLYVMLIG 199 +KI DFG SK S + GTP Y+APEVL G + D WS GV L++ L G Sbjct: 368 IKITDFGQSKILGETSLMRTLCGTPTYLAPEVLVSNGTAGYSRAVDCWSLGVILFICLSG 427 Query: 200 SYPFEDPEDPRNFRKTISRILGVQYSIPD-YVRVSSDCRRLLSQIFTADPSKRITIAEIK 376 PF + + + + I+ G IP+ + VS + L+ ++ DP R+T E Sbjct: 428 YPPFSEHKTQVSLKDQITS--GKYNFIPEVWTDVSEEALDLVKKLLVVDPKARLTTEEAL 485 Query: 377 KLPW----YLKSLPKEIAERDRANFKEPEKATETAASAAQPVE 493 PW Y+K +++ +++ + P +T +S +P+E Sbjct: 486 NHPWLQDEYMKKKFQDLLVQEKNSVTLPVAPAQT-SSQKRPLE 527
>ATG1_ASPFU (Q4WPF2) Serine/threonine-protein kinase atg1 (EC 2.7.11.1)| (Autophagy-related protein 1) Length = 973 Score = 67.8 bits (164), Expect = 2e-11 Identities = 43/156 (27%), Positives = 76/156 (48%) Frame = +2 Query: 20 PRVKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIG 199 P +KI DFG+++S S + G+P Y+APE+L ++YD K AD+WS G LY M++G Sbjct: 208 PLLKIADFGFARSLPATSLAETLCGSPLYMAPEILRYEKYDAK-ADLWSVGTVLYEMVVG 266 Query: 200 SYPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKK 379 PF RK +++ P+ S + + L+ + +P +R+ + + Sbjct: 267 KPPFRATNHVELLRKIEKGEDRIKF--PEENPASDEIKALIRALLKRNPVERLNFPDFFQ 324 Query: 380 LPWYLKSLPKEIAERDRANFKEPEKATETAASAAQP 487 +P +A+ + + P ETA + +P Sbjct: 325 NGVITSPIPGLVADDLPSIPQGPPADPETAEATPRP 360
>KRAC_DICDI (P54644) RAC-family serine/threonine-protein kinase homolog (EC| 2.7.11.1) Length = 444 Score = 67.8 bits (164), Expect = 2e-11 Identities = 48/127 (37%), Positives = 62/127 (48%), Gaps = 2/127 (1%) Frame = +2 Query: 38 DFGYSKSALLHSKPKPTV--GTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSYPF 211 DFG K LL K GTP Y+APEVL Y GK D WS G LY ML G PF Sbjct: 261 DFGLCKEGLLTPTDKTGTFCGTPEYLAPEVLQGNGY-GKQVDWWSFGSLLYEMLTGLPPF 319 Query: 212 EDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLPWY 391 + + +RK I+ + S P + +S D R LL Q+ DP KR+ + K + Sbjct: 320 YNQDVQEMYRK----IMMEKLSFPHF--ISPDARSLLEQLLERDPEKRLADPNLIKRHPF 373 Query: 392 LKSLPKE 412 +S+ E Sbjct: 374 FRSIDWE 380
>CHK1_SCHPO (P34208) Serine/threonine-protein kinase chk1 (EC 2.7.11.1)| (Checkpoint kinase 1) Length = 496 Score = 67.4 bits (163), Expect = 2e-11 Identities = 43/138 (31%), Positives = 72/138 (52%), Gaps = 11/138 (7%) Frame = +2 Query: 26 VKICDFGYS-------KSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLY 184 +KI DFG++ KS LL+S VG+P Y APE+ ++YDG DVWSCG+ L+ Sbjct: 151 LKISDFGFASLFSYKGKSRLLNSP----VGSPPYAAPEIT--QQYDGSKVDVWSCGIILF 204 Query: 185 VMLIGSYPFED----PEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSK 352 +L+G+ P+++ D ++K R S + +S +++ + +DP K Sbjct: 205 ALLLGNTPWDEAISNTGDYLLYKKQCER-----PSYHPWNLLSPGAYSIITGMLRSDPFK 259 Query: 353 RITIAEIKKLPWYLKSLP 406 R ++ + + PW S P Sbjct: 260 RYSVKHVVQHPWLTSSTP 277
>PLK1_XENTR (P62205) Serine/threonine-protein kinase PLK1 (EC 2.7.11.21)| (Polo-like kinase 1) (PLK-1) (Plx1) Length = 598 Score = 67.4 bits (163), Expect = 2e-11 Identities = 41/117 (35%), Positives = 66/117 (56%), Gaps = 1/117 (0%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTV-GTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGS 202 VKI DFG + + K T+ GTP YIAPEVL +K + +V D+WS G +Y +L+G Sbjct: 181 VKIGDFGLATKVEYDGERKKTLCGTPNYIAPEVLGKKGHSFEV-DIWSIGCIMYTLLVGK 239 Query: 203 YPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEI 373 PFE ++T RI +YS+P ++ + L+ ++ ++P+ R TI ++ Sbjct: 240 PPFE----TSCLKETYMRIKKNEYSVPKHINPMATA--LIQKMLRSEPTSRPTIDDL 290
>KCC1G_MOUSE (Q91VB2) Calcium/calmodulin-dependent protein kinase type 1G (EC| 2.7.11.17) (CaM kinase IG) (CaM kinase I gamma) (CaMKI gamma) (CaMKI-gamma) (CaM-KI gamma) (CaMKIG) (CaMK-like CREB kinase III) (CLICK III) Length = 477 Score = 67.4 bits (163), Expect = 2e-11 Identities = 38/122 (31%), Positives = 60/122 (49%) Frame = +2 Query: 23 RVKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGS 202 ++ I DFG SK + GTP Y+APEVL++K Y K D WS GV Y++L G Sbjct: 159 KIMITDFGLSKMEQ-NGVMSTACGTPGYVAPEVLAQKPYS-KAVDCWSIGVITYILLCGY 216 Query: 203 YPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKL 382 PF + + + F K ++ P + +S + + + DP++R T + + Sbjct: 217 PPFYEETESKLFEKIKEGY--YEFESPFWDDISESAKDFICHLLEKDPNERYTCEKALRH 274 Query: 383 PW 388 PW Sbjct: 275 PW 276
>KCC1G_RAT (Q7TNJ7) Calcium/calmodulin-dependent protein kinase type 1G (EC| 2.7.11.17) (CaM kinase IG) (CaM kinase I gamma) (CaMKI gamma) (CaMKI-gamma) (CaM-KI gamma) (CaMKIG) (CaMK-like CREB kinase III) (CLICK III) Length = 476 Score = 67.4 bits (163), Expect = 2e-11 Identities = 38/122 (31%), Positives = 60/122 (49%) Frame = +2 Query: 23 RVKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGS 202 ++ I DFG SK + GTP Y+APEVL++K Y K D WS GV Y++L G Sbjct: 159 KIMITDFGLSKMEQ-NGVMSTACGTPGYVAPEVLAQKPYS-KAVDCWSIGVITYILLCGY 216 Query: 203 YPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKL 382 PF + + + F K ++ P + +S + + + DP++R T + + Sbjct: 217 PPFYEETESKLFEKIKEGY--YEFESPFWDDISESAKDFICHLLEKDPNERYTCEKALRH 274 Query: 383 PW 388 PW Sbjct: 275 PW 276
>PLK1_CAEEL (P34331) Serine/threonine-protein kinase plk-1 (EC 2.7.11.21)| (Polo-like kinase 1) Length = 649 Score = 67.4 bits (163), Expect = 2e-11 Identities = 39/118 (33%), Positives = 65/118 (55%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSY 205 VKI DFG + + + K GTP YIAPEVL++ + +V D+W+ G LY++L G Sbjct: 176 VKIGDFGLATTVNGDERKKTLCGTPNYIAPEVLNKAGHSFEV-DIWAVGCILYILLFGQP 234 Query: 206 PFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKK 379 PFE ++ +T SRI Y+IP + L+ ++ +P++R T ++++ Sbjct: 235 PFES----KSLEETYSRIRHNNYTIPSI--ATQPAASLIRKMLDPEPTRRPTAKQVQR 286
>HUNK_PANTR (Q68UT7) Hormonally up-regulated neu tumor-associated kinase (EC| 2.7.11.1) Length = 714 Score = 67.4 bits (163), Expect = 2e-11 Identities = 48/147 (32%), Positives = 76/147 (51%), Gaps = 7/147 (4%) Frame = +2 Query: 26 VKICDFGYSKSA--LLHSKPKPT-VGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLI 196 +K+ DFG S A L +S P T G+PAY APE+L+RK+Y K+ DVWS GV +Y ML Sbjct: 200 IKLIDFGLSNCAGILGYSDPFSTQCGSPAYAAPELLARKKYGPKI-DVWSIGVNMYAMLT 258 Query: 197 GSYPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIK 376 G+ PF +P + R +++ + + P ++S+ L + DP KR I + Sbjct: 259 GTLPF--TVEPFSLRALYQKMVDKEMN-PLPTQLSTGAISFLRSLLEPDPVKRPNIQQAL 315 Query: 377 KLPW----YLKSLPKEIAERDRANFKE 445 W Y +P + +R + ++ Sbjct: 316 ANRWLNENYTGKVPCNVTYPNRISLED 342
>HUNK_HUMAN (P57058) Hormonally up-regulated neu tumor-associated kinase (EC| 2.7.11.1) (Serine/threonine-protein kinase MAK-V) (B19) Length = 714 Score = 67.4 bits (163), Expect = 2e-11 Identities = 48/147 (32%), Positives = 76/147 (51%), Gaps = 7/147 (4%) Frame = +2 Query: 26 VKICDFGYSKSA--LLHSKPKPT-VGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLI 196 +K+ DFG S A L +S P T G+PAY APE+L+RK+Y K+ DVWS GV +Y ML Sbjct: 200 IKLIDFGLSNCAGILGYSDPFSTQCGSPAYAAPELLARKKYGPKI-DVWSIGVNMYAMLT 258 Query: 197 GSYPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIK 376 G+ PF +P + R +++ + + P ++S+ L + DP KR I + Sbjct: 259 GTLPF--TVEPFSLRALYQKMVDKEMN-PLPTQLSTGAISFLRSLLEPDPVKRPNIQQAL 315 Query: 377 KLPW----YLKSLPKEIAERDRANFKE 445 W Y +P + +R + ++ Sbjct: 316 ANRWLNENYTGKVPCNVTYPNRISLED 342
>KPCD_MOUSE (P28867) Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta)| Length = 674 Score = 67.4 bits (163), Expect = 2e-11 Identities = 41/135 (30%), Positives = 67/135 (49%), Gaps = 2/135 (1%) Frame = +2 Query: 26 VKICDFGYSKSALL-HSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGS 202 +KI DFG K + + GTP YIAPE+L +Y V D WS GV LY MLIG Sbjct: 485 IKIADFGMCKENIFGEGRASTFCGTPDYIAPEILQGLKYSFSV-DWWSFGVLLYEMLIGQ 543 Query: 203 YPFEDPEDPRNFRKTISRILGVQYSIPDYVR-VSSDCRRLLSQIFTADPSKRITIAEIKK 379 PF ++ F ++ P Y R ++ + + ++ ++F DP KR+ + + Sbjct: 544 SPFHGDDEDELFE-------SIRVDTPHYPRWITKESKDIMEKLFERDPDKRLGVTGNIR 596 Query: 380 LPWYLKSLPKEIAER 424 + + K++ + E+ Sbjct: 597 IHPFFKTINWSLLEK 611
>ATG1_EMENI (Q5BCU8) Serine/threonine-protein kinase atg1 (EC 2.7.11.1)| (Autophagy-related protein 1) Length = 935 Score = 67.4 bits (163), Expect = 2e-11 Identities = 38/117 (32%), Positives = 63/117 (53%) Frame = +2 Query: 20 PRVKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIG 199 P +K+ DFG+++S S + G+P Y+APE+L ++YD K AD+WS G LY M++G Sbjct: 212 PLLKLADFGFARSLPATSLAETLCGSPLYMAPEILRYEKYDAK-ADLWSVGTVLYEMVVG 270 Query: 200 SYPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAE 370 PF RK + +++ P+ S D + L+ + +P R+T A+ Sbjct: 271 KPPFRATNHVELLRKIETARDRIKF--PEENPASDDIKALVRGLLKFNPVVRMTFAD 325
>AURKC_HUMAN (Q9UQB9) Serine/threonine-protein kinase 13 (EC 2.7.11.1)| (Aurora/Ipl1/Eg2 protein 2) (Aurora/Ipl1-related kinase 3) (Aurora-C) Length = 309 Score = 67.0 bits (162), Expect = 3e-11 Identities = 44/124 (35%), Positives = 65/124 (52%), Gaps = 3/124 (2%) Frame = +2 Query: 26 VKICDFGYSKSALLHS---KPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLI 196 VKI DFG+S +H+ + K GT Y+ PE++ + YD KV D+W GV Y +L+ Sbjct: 180 VKIADFGWS----VHTPSLRRKTMCGTLDYLPPEMIEGRTYDEKV-DLWCIGVLCYELLV 234 Query: 197 GSYPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIK 376 G PFE +R RIL V P + + R L+S++ P +R+ +A+I Sbjct: 235 GYPPFESASHSETYR----RILKVDVRFP--LSMPLGARDLISRLLRYQPLERLPLAQIL 288 Query: 377 KLPW 388 K PW Sbjct: 289 KHPW 292
>KOIA_SCHPO (Q9Y7J6) Putative serine/threonine-protein kinase C1778.10c (EC| 2.7.11.1) Length = 550 Score = 67.0 bits (162), Expect = 3e-11 Identities = 45/130 (34%), Positives = 67/130 (51%), Gaps = 8/130 (6%) Frame = +2 Query: 26 VKICDFG--------YSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTL 181 VKI DFG Y S + P VGT Y+APE+LSR+ K +D+W+ + Sbjct: 192 VKITDFGTAKILPPKYVNSPDYTTFPSSFVGTAEYVAPELLSRQVVS-KSSDLWAFACVV 250 Query: 182 YVMLIGSYPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRIT 361 Y M++GS PF +P N K +I+ ++Y +P + D L S +F PS R T Sbjct: 251 YQMIVGSPPFHG-SNPNNIFK---KIMSLEYELPKL--LPPDIVPLFSHLFRIQPSDRST 304 Query: 362 IAEIKKLPWY 391 +IK+ P++ Sbjct: 305 TQQIKQFPFF 314
>PHKG2_HUMAN (P15735) Phosphorylase b kinase gamma catalytic chain, testis/liver| isoform (EC 2.7.11.19) (PHK-gamma-T) (Phosphorylase kinase gamma subunit 2) (PSK-C3) Length = 406 Score = 67.0 bits (162), Expect = 3e-11 Identities = 43/144 (29%), Positives = 71/144 (49%), Gaps = 8/144 (5%) Frame = +2 Query: 23 RVKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYD-----GKVADVWSCGVTLYV 187 ++++ DFG+S K + GTP Y+APE+L + GK D+W+CGV L+ Sbjct: 166 QIRLSDFGFSCHLEPGEKLRELCGTPGYLAPEILKCSMDETHPGYGKEVDLWACGVILFT 225 Query: 188 MLIGSYPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIA 367 +L GS PF R + Q+S P++ SS + L+S++ DP R+T Sbjct: 226 LLAGSPPFWHRRQILMLRMIMEG--QYQFSSPEWDDRSSTVKDLISRLLQVDPEARLTAE 283 Query: 368 EIKKLPWYLK---SLPKEIAERDR 430 + + P++ + S P + R R Sbjct: 284 QALQHPFFERCEGSQPWNLTPRQR 307
>KPCD_CANFA (Q5PU49) Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta)| Length = 674 Score = 66.6 bits (161), Expect = 4e-11 Identities = 43/135 (31%), Positives = 67/135 (49%), Gaps = 2/135 (1%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTV-GTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGS 202 +KI DFG K + K T GTP YIAPE+L +Y V D WS GV LY MLIG Sbjct: 485 IKIADFGMCKENIFGEKQASTFCGTPDYIAPEILQGLKYSFSV-DWWSFGVLLYEMLIGQ 543 Query: 203 YPFEDPEDPRNFRKTISRILGVQYSIPDYVR-VSSDCRRLLSQIFTADPSKRITIAEIKK 379 PF ++ F ++ P Y R ++ + + +L ++ D +KR+ + K Sbjct: 544 SPFHGDDEDELFE-------SIRVDTPHYPRWITKESKDILEKLLERDTTKRLGVTGNIK 596 Query: 380 LPWYLKSLPKEIAER 424 + + K++ + E+ Sbjct: 597 IHPFFKTINWTLLEK 611
>KPCT_MOUSE (Q02111) Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta)| Length = 707 Score = 66.6 bits (161), Expect = 4e-11 Identities = 44/137 (32%), Positives = 73/137 (53%), Gaps = 3/137 (2%) Frame = +2 Query: 26 VKICDFGYSKSALL-HSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGS 202 +KI DFG K +L +K GTP YIAPE+L ++Y+ V D WS GV +Y MLIG Sbjct: 518 IKIADFGMCKENMLGDAKTNTFCGTPDYIAPEILLGQKYNHSV-DWWSFGVLVYEMLIGQ 576 Query: 203 YPFEDPEDPRNFRKTISRILGVQYSIPDYVR-VSSDCRRLLSQIFTADPSKRITI-AEIK 376 PF ++ F ++ P Y R + + + LL ++F +P KR+ + +I+ Sbjct: 577 SPFHGQDEEELFH-------SIRMDNPFYPRWLEREAKDLLVKLFVREPEKRLGVRGDIR 629 Query: 377 KLPWYLKSLPKEIAERD 427 + P + + +E+ ++ Sbjct: 630 QHPLFREINWEELERKE 646
>ATG1_COLLN (P87248) Serine/threonine-protein kinase ATG1 (EC 2.7.11.1)| (Autophagy-related protein 1) (Colletotrichum lindemuthianum kinase 1) Length = 675 Score = 66.6 bits (161), Expect = 4e-11 Identities = 41/129 (31%), Positives = 64/129 (49%) Frame = +2 Query: 20 PRVKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIG 199 P +K+ DFG+++ S G+P Y+APE+L + YD K AD+WS G LY M+ G Sbjct: 208 PMLKLADFGFARVLPSTSLADTLCGSPLYMAPEILRYERYDAK-ADLWSVGTVLYEMITG 266 Query: 200 SYPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKK 379 PF RK + V+Y P VS D +L+ ++ T +P +R+ + Sbjct: 267 RPPFRARNHVELLRKIEATEDKVKY--PKDAVVSKDLVKLIGKLLTRNPVERMRFEDFFN 324 Query: 380 LPWYLKSLP 406 P + +P Sbjct: 325 DPVVVGPIP 333
>DAPK3_RAT (O88764) Death-associated protein kinase 3 (EC 2.7.11.1) (DAP| kinase 3) (DAP-like kinase) (Dlk) (ZIP-kinase) Length = 448 Score = 66.6 bits (161), Expect = 4e-11 Identities = 38/126 (30%), Positives = 67/126 (53%), Gaps = 2/126 (1%) Frame = +2 Query: 17 TPRVKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLI 196 +PR+K+ DFG + S+ K GTP ++APE+++ + G AD+WS GV Y++L Sbjct: 154 SPRIKLIDFGIAHRIEAGSEFKNIFGTPEFVAPEIVNYEPL-GLEADMWSIGVITYILLS 212 Query: 197 GSYPFEDPEDPRNFRKTISRILGVQYSIPD--YVRVSSDCRRLLSQIFTADPSKRITIAE 370 G+ PF ++T++ I V Y + + S + + ++ DP +R+TIA+ Sbjct: 213 GASPFLG----ETKQETLTNISAVNYDFDEEYFSSTSELAKDFIRRLLVKDPKRRMTIAQ 268 Query: 371 IKKLPW 388 + W Sbjct: 269 SLEHSW 274
>DAPK3_MOUSE (O54784) Death-associated protein kinase 3 (EC 2.7.11.1) (DAP| kinase 3) (DAP-like kinase) (Dlk) (ZIP-kinase) Length = 448 Score = 66.6 bits (161), Expect = 4e-11 Identities = 38/126 (30%), Positives = 67/126 (53%), Gaps = 2/126 (1%) Frame = +2 Query: 17 TPRVKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLI 196 +PR+K+ DFG + S+ K GTP ++APE+++ + G AD+WS GV Y++L Sbjct: 154 SPRIKLIDFGIAHRIEAGSEFKNIFGTPEFVAPEIVNYEPL-GLEADMWSIGVITYILLS 212 Query: 197 GSYPFEDPEDPRNFRKTISRILGVQYSIPD--YVRVSSDCRRLLSQIFTADPSKRITIAE 370 G+ PF ++T++ I V Y + + S + + ++ DP +R+TIA+ Sbjct: 213 GASPFLG----ETKQETLTNISAVNYDFDEEYFSSTSELAKDFIRRLLVKDPKRRMTIAQ 268 Query: 371 IKKLPW 388 + W Sbjct: 269 SLEHSW 274
>HUNK_MOUSE (O88866) Hormonally up-regulated neu tumor-associated kinase (EC| 2.7.11.1) (Serine/threonine-protein kinase MAK-V) Length = 714 Score = 66.6 bits (161), Expect = 4e-11 Identities = 48/147 (32%), Positives = 75/147 (51%), Gaps = 7/147 (4%) Frame = +2 Query: 26 VKICDFGYSKSA--LLHSKPKPT-VGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLI 196 +K+ DFG S A L +S P T G+PAY APE+L+RK+Y K+ DVWS GV +Y ML Sbjct: 200 IKLIDFGLSNCAGILGYSDPFSTQCGSPAYAAPELLARKKYGPKI-DVWSIGVNMYAMLT 258 Query: 197 GSYPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIK 376 G+ PF +P + R +++ + P ++S+ L + DP KR I + Sbjct: 259 GTLPF--TVEPFSLRALYQKMVDKAMN-PLPTQLSTGAVNFLRSLLEPDPVKRPNIQQAL 315 Query: 377 KLPW----YLKSLPKEIAERDRANFKE 445 W Y +P + +R + ++ Sbjct: 316 ANRWLNENYTGKVPCNVTYPNRISLED 342
>PLK4_MOUSE (Q64702) Serine/threonine-protein kinase PLK4 (EC 2.7.11.21)| (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase Sak) (Serine/threonine-protein kinase 18) Length = 925 Score = 66.6 bits (161), Expect = 4e-11 Identities = 36/122 (29%), Positives = 67/122 (54%), Gaps = 1/122 (0%) Frame = +2 Query: 26 VKICDFGYSKSALL-HSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGS 202 +KI DFG + + H K GTP YI+PE+ +R + G +D+WS G Y +LIG Sbjct: 150 IKIADFGLATQLNMPHEKHYTLCGTPNYISPEIATRSAH-GLESDIWSLGCMFYTLLIGR 208 Query: 203 YPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKL 382 PF D + T+++++ Y +P + +S + + L+ Q+ +P+ R++++ + Sbjct: 209 PPF----DTDTVKNTLNKVVLADYEMPAF--LSREAQDLIHQLLRRNPADRLSLSSVLDH 262 Query: 383 PW 388 P+ Sbjct: 263 PF 264
>CDPK2_ORYSA (P53683) Calcium-dependent protein kinase, isoform 2 (EC 2.7.11.1)| (CDPK 2) Length = 533 Score = 66.6 bits (161), Expect = 4e-11 Identities = 42/121 (34%), Positives = 62/121 (51%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSY 205 +K DFG S + VG+ Y+APEVL R+ Y GK DVWS GV LY++L G Sbjct: 226 LKATDFGLSVFIEEGKMYRDIVGSAYYVAPEVL-RRNY-GKEIDVWSAGVILYILLSGVP 283 Query: 206 PFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLP 385 PF + F + + + + +S + L+ ++ T DP KRIT A++ + P Sbjct: 284 PFWAETEKGIFDAILQG--EIDFESQPWPSISESAKDLVRKMLTQDPKKRITSAQVLQHP 341 Query: 386 W 388 W Sbjct: 342 W 342
>ATG1_CANGA (Q6FL58) Serine/threonine-protein kinase ATG1 (EC 2.7.11.1)| (Autophagy-related protein 1) Length = 942 Score = 66.6 bits (161), Expect = 4e-11 Identities = 40/117 (34%), Positives = 62/117 (52%) Frame = +2 Query: 20 PRVKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIG 199 P +KI DFG+++ S + G+P Y+APE+L+ ++Y+ K AD+WS G L+ M G Sbjct: 192 PILKIADFGFARFLPSTSLAETLCGSPLYMAPEILNYQKYNAK-ADLWSVGTVLFEMCCG 250 Query: 200 SYPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAE 370 PF F+K I R + + P+ V + L+ + T DP+KRI E Sbjct: 251 VPPFTASNHLELFKK-IKRAHD-EINFPEVCEVEDGLKELICSLLTFDPAKRIGFEE 305
>CDPK_SOYBN (P28583) Calcium-dependent protein kinase SK5 (EC 2.7.11.1) (CDPK)| Length = 508 Score = 66.2 bits (160), Expect = 5e-11 Identities = 43/123 (34%), Positives = 65/123 (52%), Gaps = 1/123 (0%) Frame = +2 Query: 23 RVKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGS 202 ++K DFG S VG+P Y+APEVL RK Y G +DVWS GV LY++L G Sbjct: 174 KLKATDFGLSVFYKPGESFCDVVGSPYYVAPEVL-RKLY-GPESDVWSAGVILYILLSGV 231 Query: 203 YPFEDPEDPRNFRKTISRILG-VQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKK 379 PF +P FR+ +LG + + + +S + L+ ++ +P R+T E+ + Sbjct: 232 PPFWAESEPGIFRQI---LLGKLDFHSEPWPSISDSAKDLIRKMLDQNPKTRLTAHEVLR 288 Query: 380 LPW 388 PW Sbjct: 289 HPW 291
>KCC1G_HUMAN (Q96NX5) Calcium/calmodulin-dependent protein kinase type 1G (EC| 2.7.11.17) (CaM kinase IG) (CaM kinase I gamma) (CaMKI gamma) (CaMKI-gamma) (CaM-KI gamma) (CaMKIG) (CaMK-like CREB kinase III) (CLICK III) Length = 476 Score = 66.2 bits (160), Expect = 5e-11 Identities = 38/122 (31%), Positives = 59/122 (48%) Frame = +2 Query: 23 RVKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGS 202 ++ I DFG SK + GTP Y+APEVL++K Y K D WS GV Y++L G Sbjct: 159 KIMITDFGLSKMEQ-NGIMSTACGTPGYVAPEVLAQKPYS-KAVDCWSIGVITYILLCGY 216 Query: 203 YPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKL 382 PF + + + F K ++ P + +S + + + DP++R T + Sbjct: 217 PPFYEETESKLFEKIKEGY--YEFESPFWDDISESAKDFICHLLEKDPNERYTCEKALSH 274 Query: 383 PW 388 PW Sbjct: 275 PW 276
>CDPK_DAUCA (P28582) Calcium-dependent protein kinase (EC 2.7.11.1) (CDPK)| Length = 532 Score = 66.2 bits (160), Expect = 5e-11 Identities = 41/121 (33%), Positives = 63/121 (52%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSY 205 +K DFG S + VG+ Y+APEVL R+ Y GK D+WS GV LY++L G Sbjct: 222 LKATDFGLSVFIEEGKVYRNIVGSAYYVAPEVL-RRSY-GKEIDIWSAGVILYILLSGVP 279 Query: 206 PFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLP 385 PF + F + + + + + VS+ + L+ ++ T DP +RIT A++ P Sbjct: 280 PFWAENEKGIFDAILEGV--IDFESEPWPSVSNSAKDLVRKMLTQDPRRRITSAQVLDHP 337 Query: 386 W 388 W Sbjct: 338 W 338
>CDPK1_ORYSA (P53682) Calcium-dependent protein kinase, isoform 1 (EC 2.7.11.1)| (CDPK 1) Length = 534 Score = 66.2 bits (160), Expect = 5e-11 Identities = 42/129 (32%), Positives = 62/129 (48%) Frame = +2 Query: 2 LDGSPTPRVKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTL 181 LD VK DFG S + VG+P YIAPEVL ++ G AD+W+ GV L Sbjct: 206 LDADDEFSVKAIDFGLSVFFRPGQVFREVVGSPYYIAPEVLEKRY--GPEADIWTAGVIL 263 Query: 182 YVMLIGSYPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRIT 361 YV+L G PF + K + + + + R+S + L+ ++ PS+R+ Sbjct: 264 YVLLTGVPPFWADTQSGIYEKVLDG--RIDFKSNRWPRISDSAKDLIKKMLCPYPSERLK 321 Query: 362 IAEIKKLPW 388 E+ K PW Sbjct: 322 AHEVLKHPW 330
>PHKG2_MOUSE (Q9DB30) Phosphorylase b kinase gamma catalytic chain, testis/liver| isoform (EC 2.7.11.19) (PHK-gamma-T) (Phosphorylase kinase gamma subunit 2) Length = 406 Score = 66.2 bits (160), Expect = 5e-11 Identities = 41/144 (28%), Positives = 71/144 (49%), Gaps = 8/144 (5%) Frame = +2 Query: 23 RVKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYD-----GKVADVWSCGVTLYV 187 ++++ DFG+S K + GTP Y+APE+L + GK D+W+CGV L+ Sbjct: 166 QIRLSDFGFSCHLEAGEKLRELCGTPGYLAPEILKCSMDETHPGYGKEVDLWACGVILFT 225 Query: 188 MLIGSYPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIA 367 +L GS PF R + Q++ P++ S+ + L+S++ DP R+T Sbjct: 226 LLAGSPPFWHRRQILMLRMIMEG--QYQFTSPEWDDCSNTVKDLISKLLQVDPEARLTAE 283 Query: 368 EIKKLPWYLK---SLPKEIAERDR 430 + + P++ + S P + R R Sbjct: 284 QALQHPFFERCEGSQPWNLTPRQR 307
>PCK2_SCHPO (P36583) Protein kinase C-like 2 (EC 2.7.11.13)| Length = 1016 Score = 65.9 bits (159), Expect = 7e-11 Identities = 40/117 (34%), Positives = 59/117 (50%), Gaps = 1/117 (0%) Frame = +2 Query: 11 SPTPRVKICDFGYSKSALLHSKPKPTV-GTPAYIAPEVLSRKEYDGKVADVWSCGVTLYV 187 SP VK+ D+G K + H T GTP ++APE+L ++Y V D W+ GV +Y Sbjct: 817 SPDGHVKVADYGLCKEDMWHDNTTATFCGTPEFMAPEILLEQQYTRSV-DWWAFGVLIYQ 875 Query: 188 MLIGSYPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRI 358 ML+G PF ++ F IL + P + + D +L Q+ T DP KR+ Sbjct: 876 MLLGQSPFRGEDEEEIF----DAILSDEPLYP--IHMPRDSVSILQQLLTRDPKKRL 926
>AKT3_MOUSE (Q9WUA6) RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-gamma) (Protein kinase Akt-3) (Protein kinase B, gamma) (PKB gamma) Length = 479 Score = 65.9 bits (159), Expect = 7e-11 Identities = 41/112 (36%), Positives = 57/112 (50%), Gaps = 1/112 (0%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTV-GTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGS 202 +KI DFG K + + T GTP Y+APEVL +Y G+ D W GV +Y M+ G Sbjct: 285 IKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDY-GRAVDWWGLGVVMYEMMCGR 343 Query: 203 YPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRI 358 PF + ++ K IL P +SSD + LLS + DP+KR+ Sbjct: 344 LPFYN----QDHEKLFELILMEDIKFPR--TLSSDAKSLLSGLLIKDPNKRL 389
>AKT3_HUMAN (Q9Y243) RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-gamma) (Protein kinase Akt-3) (Protein kinase B, gamma) (PKB gamma) (STK-2) Length = 479 Score = 65.9 bits (159), Expect = 7e-11 Identities = 41/112 (36%), Positives = 57/112 (50%), Gaps = 1/112 (0%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTV-GTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGS 202 +KI DFG K + + T GTP Y+APEVL +Y G+ D W GV +Y M+ G Sbjct: 285 IKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDY-GRAVDWWGLGVVMYEMMCGR 343 Query: 203 YPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRI 358 PF + ++ K IL P +SSD + LLS + DP+KR+ Sbjct: 344 LPFYN----QDHEKLFELILMEDIKFPR--TLSSDAKSLLSGLLIKDPNKRL 389
>SRK1_SCHPO (O94547) Serine/threonine-protein kinase srk1 (EC 2.7.11.1)| (Sty1-regulated kinase 1) Length = 580 Score = 65.9 bits (159), Expect = 7e-11 Identities = 51/168 (30%), Positives = 72/168 (42%), Gaps = 13/168 (7%) Frame = +2 Query: 23 RVKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGS 202 R+++ DFG SK + S + GT Y APE++ + Y K D+W+ G LY +L G Sbjct: 303 RIRLADFGLSK-VVWDSHTQTPCGTMGYTAPEIVRDERYS-KGVDMWALGCVLYTILCGF 360 Query: 203 YPFEDPEDPRNFRKTISRILGVQYSI--PDYVRVSSDCRRLLSQIFTADPSKRITIAEIK 376 PF D E K +SR +YS P + +S + L+S + T DP R I + Sbjct: 361 PPFYD-ESISLLTKKVSR---GEYSFLSPWWDDISKSAKDLISHLLTVDPESRYDIHQFL 416 Query: 377 KLPWYLKSLPKEIAERDRAN-----------FKEPEKATETAASAAQP 487 PW S D N F EPE ++A P Sbjct: 417 AHPWISGSREPTFPATDAPNTAQRENPFTYDFLEPEDVAAAGSAARTP 464
>AKT3_RAT (Q63484) RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-gamma) (Protein kinase Akt-3) (Protein kinase B, gamma) (PKB gamma) Length = 454 Score = 65.9 bits (159), Expect = 7e-11 Identities = 41/112 (36%), Positives = 57/112 (50%), Gaps = 1/112 (0%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTV-GTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGS 202 +KI DFG K + + T GTP Y+APEVL +Y G+ D W GV +Y M+ G Sbjct: 285 IKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDY-GRAVDWWGLGVVMYEMMCGR 343 Query: 203 YPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRI 358 PF + ++ K IL P +SSD + LLS + DP+KR+ Sbjct: 344 LPFYN----QDHEKLFELILMEDIKFPR--TLSSDAKSLLSGLLIKDPNKRL 389
>RCK2_YEAST (P38623) Serine/threonine-protein kinase RCK2 (EC 2.7.11.1) (CAM| kinase-like protein kinase CLK1) Length = 610 Score = 65.5 bits (158), Expect = 9e-11 Identities = 48/133 (36%), Positives = 65/133 (48%), Gaps = 4/133 (3%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSY 205 VK+ DFG SK + K GT Y APEV+ + Y KV D+W G LY ML G Sbjct: 361 VKLADFGLSKQ-IFSKNTKTPCGTVGYTAPEVVKDEHYSMKV-DMWGIGCVLYTMLCGFP 418 Query: 206 PFEDPEDPRNFRKTISRILGVQYSI--PDYVRVSSDCRRLLSQIFTADPSKRITIAEIKK 379 PF D E + ISR +Y+ P + +S+ + +S++ +PSKR I + Sbjct: 419 PFYD-EKIDTLTEKISR---GEYTFLKPWWDEISAGAKNAVSKLLELEPSKRYDIDQFLD 474 Query: 380 LPWY--LKSLPKE 412 PW LPKE Sbjct: 475 DPWLNTFDCLPKE 487
>CDPK1_ARATH (Q06850) Calcium-dependent protein kinase, isoform AK1 (EC| 2.7.11.1) (CDPK) Length = 610 Score = 65.5 bits (158), Expect = 9e-11 Identities = 42/121 (34%), Positives = 61/121 (50%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSY 205 +K DFG S VG+P Y+APEVL RK Y G ADVWS GV +Y++L G Sbjct: 291 LKTIDFGLSMFFKPDDVFTDVVGSPYYVAPEVL-RKRY-GPEADVWSAGVIVYILLSGVP 348 Query: 206 PFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLP 385 PF + F + + L +S + +S + L+ ++ DP KR+T ++ P Sbjct: 349 PFWAETEQGIFEQVLHGDL--DFSSDPWPSISESAKDLVRKMLVRDPKKRLTAHQVLCHP 406 Query: 386 W 388 W Sbjct: 407 W 407
>CHK1_XENLA (Q6DE87) Serine/threonine-protein kinase Chk1 (EC 2.7.11.1) (xChk1| protein) Length = 474 Score = 65.5 bits (158), Expect = 9e-11 Identities = 38/132 (28%), Positives = 66/132 (50%), Gaps = 3/132 (2%) Frame = +2 Query: 23 RVKICDFGYSKSALLHSKPK---PTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVML 193 ++KI DFG + + K + GT Y+APE++ + + DVWSCG+ L ML Sbjct: 143 QLKISDFGLATVFRHNGKERLLNKMCGTLPYVAPELIKSRAFHADPVDVWSCGIVLTAML 202 Query: 194 IGSYPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEI 373 G P++ P + + + + + ++S+ LL ++ T +P RITI +I Sbjct: 203 AGELPWDQPNE---VCQEYCDWKEKNHYLTPWKKISATPLALLCKMLTENPQSRITIPDI 259 Query: 374 KKLPWYLKSLPK 409 KK W+ + + K Sbjct: 260 KKDRWFTEIIKK 271
>STK33_HUMAN (Q9BYT3) Serine/threonine-protein kinase 33 (EC 2.7.11.1)| Length = 514 Score = 65.5 bits (158), Expect = 9e-11 Identities = 40/124 (32%), Positives = 66/124 (53%), Gaps = 3/124 (2%) Frame = +2 Query: 26 VKICDFGYS--KSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIG 199 +K+ DFG + K + + + T GTP Y+APEV+S +Y + D+WS GV +Y++L G Sbjct: 261 IKVTDFGLAVKKQSRSEAMLQATCGTPIYMAPEVISAHDY-SQQCDIWSIGVVMYMLLRG 319 Query: 200 SYPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDC-RRLLSQIFTADPSKRITIAEIK 376 PF + + F L + ++ + + SDC + +L Q+ DP+ RIT E+ Sbjct: 320 EPPFLASSEEKLFELIRKGELHFENAVWNSI---SDCAKSVLKQLMKVDPAHRITAKELL 376 Query: 377 KLPW 388 W Sbjct: 377 DNQW 380
>PHKG1_HUMAN (Q16816) Phosphorylase b kinase gamma catalytic chain, skeletal| muscle isoform (EC 2.7.11.19) (Phosphorylase kinase gamma subunit 1) Length = 386 Score = 65.5 bits (158), Expect = 9e-11 Identities = 42/145 (28%), Positives = 68/145 (46%), Gaps = 6/145 (4%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYD-----GKVADVWSCGVTLYVM 190 +K+ DFG+S + + GTP+Y+APE++ + GK D+WS GV +Y + Sbjct: 163 IKLTDFGFSCQLEPGERLREVCGTPSYLAPEIIECSMNEDHPGYGKEVDMWSTGVIMYTL 222 Query: 191 LIGSYPFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAE 370 L GS PF + R +S Q+ P++ S + L+S+ P R T E Sbjct: 223 LAGSPPFWHRKQMLMLRMIMSG--NYQFGSPEWDDYSDTVKDLVSRFLVVQPQNRYTAEE 280 Query: 371 IKKLPWYLKSLPKEIAE-RDRANFK 442 P++ + L +E+ R FK Sbjct: 281 ALAHPFFQQYLVEEVRHFSPRGKFK 305
>PIM2_HUMAN (Q9P1W9) Serine/threonine-protein kinase Pim-2 (EC 2.7.11.1)| (Pim-2h) Length = 311 Score = 65.5 bits (158), Expect = 9e-11 Identities = 44/121 (36%), Positives = 57/121 (47%), Gaps = 1/121 (0%) Frame = +2 Query: 29 KICDFGYSKSALLHSKPKPTV-GTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGSY 205 K+ DFG ALLH +P GT Y PE +SR +Y A VWS G+ LY M+ G Sbjct: 179 KLIDFG--SGALLHDEPYTDFDGTRVYSPPEWISRHQYHALPATVWSLGILLYDMVCGDI 236 Query: 206 PFEDPEDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFTADPSKRITIAEIKKLP 385 PFE ++ IL + P VS DC L+ + PS R ++ EI P Sbjct: 237 PFERDQE----------ILEAELHFP--AHVSPDCCALIRRCLAPKPSSRPSLEEILLDP 284 Query: 386 W 388 W Sbjct: 285 W 285
>CHK2_HUMAN (O96017) Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (Cds1)| Length = 543 Score = 65.5 bits (158), Expect = 9e-11 Identities = 47/163 (28%), Positives = 74/163 (45%), Gaps = 7/163 (4%) Frame = +2 Query: 26 VKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDG--KVADVWSCGVTLYVMLIG 199 +KI DFG+SK S + GTP Y+APEVL G + D WS GV L++ L G Sbjct: 364 IKITDFGHSKILGETSLMRTLCGTPTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSG 423 Query: 200 SYPFEDPEDPRNFRKTISRILGVQYSIPD-YVRVSSDCRRLLSQIFTADPSKRITIAEIK 376 PF + + + I+ G IP+ + VS L+ ++ DP R T E Sbjct: 424 YPPFSEHRTQVSLKDQITS--GKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEAL 481 Query: 377 KLPWY----LKSLPKEIAERDRANFKEPEKATETAASAAQPVE 493 + PW +K +++ + + P+ + + S +P E Sbjct: 482 RHPWLQDEDMKRKFQDLLSEENESTALPQVLAQPSTSRKRPRE 524
>KCC2_SCHPO (O42844) Calcium/calmodulin-dependent protein kinase type II (EC| 2.7.11.17) (CAM kinase II) Length = 504 Score = 65.5 bits (158), Expect = 9e-11 Identities = 39/124 (31%), Positives = 65/124 (52%), Gaps = 2/124 (1%) Frame = +2 Query: 23 RVKICDFGYSKSALLHSKPKPTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLIGS 202 R+ I DFG+SK + +SK GT Y APE+++ + Y V D+W+ G L+ ML G Sbjct: 233 RILIADFGFSK-VVWNSKTATPCGTVGYAAPEIVNDELYSKNV-DMWAMGCVLHTMLCGF 290 Query: 203 YPFEDPEDPRNFRKTISRILGVQYSI--PDYVRVSSDCRRLLSQIFTADPSKRITIAEIK 376 PF D N + S+++ ++ P + +S + L++ + T DP +R I + Sbjct: 291 PPFFD----ENIKDLASKVVNGEFEFLSPWWDDISDSAKDLITHLLTVDPRERYDIHQFF 346 Query: 377 KLPW 388 + PW Sbjct: 347 QHPW 350 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 75,766,813 Number of Sequences: 219361 Number of extensions: 1708744 Number of successful extensions: 8127 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 6820 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 7167 length of database: 80,573,946 effective HSP length: 105 effective length of database: 57,541,041 effective search space used: 3970331829 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
