ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
menu 
| Clone Name | bart31h11 |
|---|---|
| Clone Library Name | barley_pub |
>AAIP_WHEAT (Q02066) Abscisic acid-inducible protein kinase (EC 2.7.11.1)| (Fragment) Length = 332 Score = 193 bits (490), Expect(2) = 9e-56 Identities = 93/94 (98%), Positives = 94/94 (100%) Frame = +3 Query: 222 GSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEHVQREIMNHRSLKHPNIIRFKEVVLTP 401 GSGNFGVAKLVRDVRT+EHFAVKFIERGHKIDEHVQREIMNHRSLKHPNIIRFKEVVLTP Sbjct: 1 GSGNFGVAKLVRDVRTKEHFAVKFIERGHKIDEHVQREIMNHRSLKHPNIIRFKEVVLTP 60 Query: 402 THLAIVMEYASGGELFQRICNAGRFSEDEGRFFF 503 THLAIVMEYASGGELFQRICNAGRFSEDEGRFFF Sbjct: 61 THLAIVMEYASGGELFQRICNAGRFSEDEGRFFF 94 Score = 43.5 bits (101), Expect(2) = 9e-56 Identities = 18/23 (78%), Positives = 19/23 (82%) Frame = +2 Query: 488 GKVLLPQLISGVSYCHSMQVCHR 556 G+ QLISGVSYCHSMQVCHR Sbjct: 90 GRFFFQQLISGVSYCHSMQVCHR 112
>SAPK1_ORYSA (Q75LR7) Serine/threonine-protein kinase SAPK1 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 1) Length = 342 Score = 192 bits (487), Expect(2) = 1e-54 Identities = 94/104 (90%), Positives = 98/104 (94%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEHVQREIMNHRSLKHPNI 371 M+RYEV+RDIGSGNFGVAKLVRDV T FAVKFIERG KIDEHVQREIMNHRSLKHPNI Sbjct: 1 MERYEVMRDIGSGNFGVAKLVRDVATNHLFAVKFIERGLKIDEHVQREIMNHRSLKHPNI 60 Query: 372 IRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFF 503 IRFKEVVLTPTHLAIVMEYA+GGELF+RICNAGRFSEDE RFFF Sbjct: 61 IRFKEVVLTPTHLAIVMEYAAGGELFERICNAGRFSEDEARFFF 104 Score = 41.2 bits (95), Expect(2) = 1e-54 Identities = 17/17 (100%), Positives = 17/17 (100%) Frame = +2 Query: 506 QLISGVSYCHSMQVCHR 556 QLISGVSYCHSMQVCHR Sbjct: 106 QLISGVSYCHSMQVCHR 122
>SAPK2_ORYSA (Q84TC6) Serine/threonine-protein kinase SAPK2 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 2) Length = 339 Score = 191 bits (486), Expect(2) = 2e-54 Identities = 91/104 (87%), Positives = 101/104 (97%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEHVQREIMNHRSLKHPNI 371 M+RYEV++DIGSGNFGVAKLVRDVRT+E FAVKFIERG KIDE+VQREIMNHRSL+HPNI Sbjct: 1 MERYEVIKDIGSGNFGVAKLVRDVRTKELFAVKFIERGQKIDENVQREIMNHRSLRHPNI 60 Query: 372 IRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFF 503 +RFKEVVLTPTHLAIVMEYA+GGELF+RIC+AGRFSEDE RFFF Sbjct: 61 VRFKEVVLTPTHLAIVMEYAAGGELFERICSAGRFSEDEARFFF 104 Score = 40.8 bits (94), Expect(2) = 2e-54 Identities = 16/17 (94%), Positives = 17/17 (100%) Frame = +2 Query: 506 QLISGVSYCHSMQVCHR 556 QLISGVSYCHSMQ+CHR Sbjct: 106 QLISGVSYCHSMQICHR 122
>SAPKA_ORYSA (Q75H77) Serine/threonine-protein kinase SAPK10 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 10) Length = 362 Score = 174 bits (441), Expect(2) = 2e-49 Identities = 84/103 (81%), Positives = 94/103 (91%) Frame = +3 Query: 195 DRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEHVQREIMNHRSLKHPNII 374 DRYE+VRDIGSGNFGVA+L+R + AVK+IERG KIDE+VQREI+NHRSL+HPNII Sbjct: 21 DRYELVRDIGSGNFGVARLMRSRADGQLVAVKYIERGDKIDENVQREIINHRSLRHPNII 80 Query: 375 RFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFF 503 RFKEV+LTPTHLAIVMEYASGGELF+RICNAGRFSEDE RFFF Sbjct: 81 RFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFF 123 Score = 41.2 bits (95), Expect(2) = 2e-49 Identities = 17/17 (100%), Positives = 17/17 (100%) Frame = +2 Query: 506 QLISGVSYCHSMQVCHR 556 QLISGVSYCHSMQVCHR Sbjct: 125 QLISGVSYCHSMQVCHR 141
>SAPK8_ORYSA (Q7Y0B9) Serine/threonine-protein kinase SAPK8 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 8) Length = 371 Score = 174 bits (440), Expect(2) = 3e-49 Identities = 84/103 (81%), Positives = 94/103 (91%) Frame = +3 Query: 195 DRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEHVQREIMNHRSLKHPNII 374 DRYE+VRDIGSGNFGVA+L+RD RT E AVK+IERG KID++VQREI+NHRSLKHPNII Sbjct: 31 DRYELVRDIGSGNFGVARLMRDRRTMELVAVKYIERGEKIDDNVQREIINHRSLKHPNII 90 Query: 375 RFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFF 503 RFKEV+LTPTHLAIVMEYASGGELF+RIC RFSEDE R+FF Sbjct: 91 RFKEVILTPTHLAIVMEYASGGELFERICKNVRFSEDEARYFF 133 Score = 41.2 bits (95), Expect(2) = 3e-49 Identities = 17/17 (100%), Positives = 17/17 (100%) Frame = +2 Query: 506 QLISGVSYCHSMQVCHR 556 QLISGVSYCHSMQVCHR Sbjct: 135 QLISGVSYCHSMQVCHR 151
>SAPK9_ORYSA (Q75V57) Serine/threonine-protein kinase SAPK9 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 9) Length = 361 Score = 170 bits (430), Expect(2) = 4e-48 Identities = 80/103 (77%), Positives = 96/103 (93%) Frame = +3 Query: 195 DRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEHVQREIMNHRSLKHPNII 374 DRYE+V++IGSGNFGVA+L+R+ + + AVK+I+RG KIDE+VQREI+NHRSL+HPNII Sbjct: 20 DRYELVKEIGSGNFGVARLMRNRASGDLVAVKYIDRGEKIDENVQREIINHRSLRHPNII 79 Query: 375 RFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFF 503 RFKEV+LTPTHLAIVMEYASGGELF+RIC+AGRFSEDE RFFF Sbjct: 80 RFKEVILTPTHLAIVMEYASGGELFERICSAGRFSEDEARFFF 122 Score = 41.2 bits (95), Expect(2) = 4e-48 Identities = 17/17 (100%), Positives = 17/17 (100%) Frame = +2 Query: 506 QLISGVSYCHSMQVCHR 556 QLISGVSYCHSMQVCHR Sbjct: 124 QLISGVSYCHSMQVCHR 140
>SAPK3_ORYSA (Q75V63) Serine/threonine-protein kinase SAPK3 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 3) (Protein kinase REK) Length = 334 Score = 168 bits (426), Expect(2) = 7e-47 Identities = 78/103 (75%), Positives = 95/103 (92%) Frame = +3 Query: 195 DRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEHVQREIMNHRSLKHPNII 374 +RYE ++++G+GNFGVA+LVRD R++E AVK+IERG KIDE+VQREI+NHRSL+HPNII Sbjct: 3 ERYEALKELGAGNFGVARLVRDKRSKELVAVKYIERGKKIDENVQREIINHRSLRHPNII 62 Query: 375 RFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFF 503 RFKEV LTPTHLAIVMEYA+GGELF++IC AGRFSEDE R+FF Sbjct: 63 RFKEVCLTPTHLAIVMEYAAGGELFEQICTAGRFSEDEARYFF 105 Score = 38.5 bits (88), Expect(2) = 7e-47 Identities = 14/17 (82%), Positives = 17/17 (100%) Frame = +2 Query: 506 QLISGVSYCHSMQVCHR 556 QLISGVSYCHS+++CHR Sbjct: 107 QLISGVSYCHSLEICHR 123
>ASK1_ARATH (P43291) Serine/threonine-protein kinase ASK1 (EC 2.7.11.1)| Length = 363 Score = 165 bits (418), Expect(2) = 2e-46 Identities = 77/104 (74%), Positives = 95/104 (91%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEHVQREIMNHRSLKHPNI 371 MD+YE+V+DIG+GNFGVA+L++ ++E A+K+IERG KIDE+V REI+NHRSL+HPNI Sbjct: 1 MDKYELVKDIGAGNFGVARLMKVKNSKELVAMKYIERGPKIDENVAREIINHRSLRHPNI 60 Query: 372 IRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFF 503 IRFKEVVLTPTHLAI MEYA+GGELF+RIC+AGRFSEDE R+FF Sbjct: 61 IRFKEVVLTPTHLAIAMEYAAGGELFERICSAGRFSEDEARYFF 104 Score = 39.7 bits (91), Expect(2) = 2e-46 Identities = 15/17 (88%), Positives = 17/17 (100%) Frame = +2 Query: 506 QLISGVSYCHSMQVCHR 556 QLISGVSYCH+MQ+CHR Sbjct: 106 QLISGVSYCHAMQICHR 122
>SAPK4_ORYSA (Q5N942) Serine/threonine-protein kinase SAPK4 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 4) Length = 360 Score = 167 bits (424), Expect(2) = 3e-46 Identities = 79/104 (75%), Positives = 93/104 (89%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEHVQREIMNHRSLKHPNI 371 M++YE VRDIGSGNFGVA+L+R+ TRE AVK IERGH+IDE+V REI+NHRSL+HPNI Sbjct: 1 MEKYEAVRDIGSGNFGVARLMRNRETRELVAVKCIERGHRIDENVYREIINHRSLRHPNI 60 Query: 372 IRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFF 503 IRFKEV+LTPTHL IVME+A+GGELF RIC+ GRFSEDE R+FF Sbjct: 61 IRFKEVILTPTHLMIVMEFAAGGELFDRICDRGRFSEDEARYFF 104 Score = 37.0 bits (84), Expect(2) = 3e-46 Identities = 14/17 (82%), Positives = 15/17 (88%) Frame = +2 Query: 506 QLISGVSYCHSMQVCHR 556 QLI GVSYCH MQ+CHR Sbjct: 106 QLICGVSYCHHMQICHR 122
>SAPK7_ORYSA (Q7XQP4) Serine/threonine-protein kinase SAPK7 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 7) Length = 359 Score = 167 bits (422), Expect(2) = 7e-46 Identities = 78/104 (75%), Positives = 95/104 (91%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEHVQREIMNHRSLKHPNI 371 M+RYE+++DIG+GNFGVA+L+R+ T+E A+K+I RG KIDE+V REI+NHRSL+HPNI Sbjct: 1 MERYELLKDIGAGNFGVARLMRNKETKELVAMKYIPRGLKIDENVAREIINHRSLRHPNI 60 Query: 372 IRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFF 503 IRFKEVV+TPTHLAIVMEYA+GGELF RICNAGRFSEDE R+FF Sbjct: 61 IRFKEVVVTPTHLAIVMEYAAGGELFDRICNAGRFSEDEARYFF 104 Score = 36.6 bits (83), Expect(2) = 7e-46 Identities = 14/17 (82%), Positives = 15/17 (88%) Frame = +2 Query: 506 QLISGVSYCHSMQVCHR 556 QLI GVSYCH MQ+CHR Sbjct: 106 QLICGVSYCHFMQICHR 122
>ASK2_ARATH (P43292) Serine/threonine-protein kinase ASK2 (EC 2.7.11.1)| Length = 353 Score = 167 bits (423), Expect(2) = 7e-46 Identities = 79/104 (75%), Positives = 93/104 (89%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEHVQREIMNHRSLKHPNI 371 MD+Y+VV+D+G+GNFGVA+L+R T+E A+K+IERG KIDE+V REI+NHRSLKHPNI Sbjct: 1 MDKYDVVKDLGAGNFGVARLLRHKDTKELVAMKYIERGRKIDENVAREIINHRSLKHPNI 60 Query: 372 IRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFF 503 IRFKEV+LTPTHLAIVMEYASGGELF RIC AGRFSE E R+FF Sbjct: 61 IRFKEVILTPTHLAIVMEYASGGELFDRICTAGRFSEAEARYFF 104 Score = 36.2 bits (82), Expect(2) = 7e-46 Identities = 13/17 (76%), Positives = 15/17 (88%) Frame = +2 Query: 506 QLISGVSYCHSMQVCHR 556 QLI GV YCHS+Q+CHR Sbjct: 106 QLICGVDYCHSLQICHR 122
>SAPK6_ORYSA (Q6ZI44) Serine/threonine-protein kinase SAPK6 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 6) Length = 365 Score = 166 bits (419), Expect(2) = 2e-45 Identities = 78/104 (75%), Positives = 95/104 (91%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEHVQREIMNHRSLKHPNI 371 M++YE+++DIGSGNFGVA+L+R+ T+E A+K+I RG KIDE+V REI+NHRSL+HPNI Sbjct: 1 MEKYELLKDIGSGNFGVARLMRNRETKELVAMKYIPRGLKIDENVAREIINHRSLRHPNI 60 Query: 372 IRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFF 503 IRFKEVVLTPTHLAIVMEYA+GGELF RIC+AGRFSEDE R+FF Sbjct: 61 IRFKEVVLTPTHLAIVMEYAAGGELFDRICSAGRFSEDESRYFF 104 Score = 36.6 bits (83), Expect(2) = 2e-45 Identities = 14/17 (82%), Positives = 15/17 (88%) Frame = +2 Query: 506 QLISGVSYCHSMQVCHR 556 QLI GVSYCH MQ+CHR Sbjct: 106 QLICGVSYCHFMQICHR 122
>SAPK5_ORYSA (Q7XKA8) Serine/threonine-protein kinase SAPK5 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 5) Length = 370 Score = 161 bits (408), Expect(2) = 2e-44 Identities = 77/104 (74%), Positives = 93/104 (89%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEHVQREIMNHRSLKHPNI 371 M++YE VR+IG+GNFGVAKL+R+ TRE A+KFIERG++IDE+V REI+NHRSL+HPNI Sbjct: 1 MEKYEPVREIGAGNFGVAKLMRNKETRELVAMKFIERGNRIDENVFREIVNHRSLRHPNI 60 Query: 372 IRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFF 503 IRFKEVV+T HLAIVMEYA+GGELF+RIC AGRF EDE R+FF Sbjct: 61 IRFKEVVVTGRHLAIVMEYAAGGELFERICEAGRFHEDEARYFF 104 Score = 37.4 bits (85), Expect(2) = 2e-44 Identities = 13/17 (76%), Positives = 16/17 (94%) Frame = +2 Query: 506 QLISGVSYCHSMQVCHR 556 QL+ GVSYCH+MQ+CHR Sbjct: 106 QLVCGVSYCHAMQICHR 122
>CIPK1_ARATH (Q8RWC9) CBL-interacting serine/threonine-protein kinase 1 (EC| 2.7.11.1) (SOS2-like protein kinase PKS13) (SNF1-related kinase 3.16) Length = 444 Score = 85.1 bits (209), Expect(2) = 3e-20 Identities = 43/108 (39%), Positives = 66/108 (61%), Gaps = 4/108 (3%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEH----VQREIMNHRSLK 359 + +YE+ R +G GNFG K +D + FAVK I++ D + ++REI + LK Sbjct: 17 LGKYELGRTLGEGNFGKVKFAKDTVSGHSFAVKIIDKSRIADLNFSLQIKREIRTLKMLK 76 Query: 360 HPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFF 503 HP+I+R EV+ + T + +VME +GGELF RI + G+ +E +GR F Sbjct: 77 HPHIVRLHEVLASKTKINMVMELVTGGELFDRIVSNGKLTETDGRKMF 124 Score = 32.7 bits (73), Expect(2) = 3e-20 Identities = 13/23 (56%), Positives = 16/23 (69%) Frame = +2 Query: 488 GKVLLPQLISGVSYCHSMQVCHR 556 G+ + QLI G+SYCHS V HR Sbjct: 120 GRKMFQQLIDGISYCHSKGVFHR 142
>KIN10_ARATH (Q38997) SNF1-related protein kinase catalytic alpha subunit KIN10| (EC 2.7.11.1) (AKIN10) (AKIN alpha2) Length = 535 Score = 81.6 bits (200), Expect(2) = 5e-18 Identities = 44/108 (40%), Positives = 61/108 (56%), Gaps = 4/108 (3%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIER----GHKIDEHVQREIMNHRSLK 359 + Y++ R +G G+FG K+ T A+K + R +++E V+REI R Sbjct: 39 LPNYKLGRTLGIGSFGRVKIAEHALTGHKVAIKILNRRKIKNMEMEEKVRREIKILRLFM 98 Query: 360 HPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFF 503 HP+IIR EV+ TPT + +VMEY + GELF I GR EDE R FF Sbjct: 99 HPHIIRLYEVIETPTDIYLVMEYVNSGELFDYIVEKGRLQEDEARNFF 146 Score = 28.5 bits (62), Expect(2) = 5e-18 Identities = 11/17 (64%), Positives = 12/17 (70%) Frame = +2 Query: 506 QLISGVSYCHSMQVCHR 556 Q+ISGV YCH V HR Sbjct: 148 QIISGVEYCHRNMVVHR 164
>CIPK1_ORYSA (Q6X4A2) CIPK-like protein 1 (EC 2.7.11.1) (OsCK1)| Length = 449 Score = 80.5 bits (197), Expect(2) = 3e-17 Identities = 38/106 (35%), Positives = 63/106 (59%), Gaps = 4/106 (3%) Frame = +3 Query: 198 RYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERG----HKIDEHVQREIMNHRSLKHP 365 +YE+ R IG G F + ++ E A+K +++ H++ E ++REI + +KHP Sbjct: 19 KYELGRTIGEGTFAKVRFAKNTENDEPVAIKILDKEKVQKHRLVEQIRREICTMKLVKHP 78 Query: 366 NIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFF 503 N++R EV+ + + IV+EY +GGELF+ I GR E+E R +F Sbjct: 79 NVVRLFEVMGSKARIFIVLEYVTGGELFEIIATNGRLKEEEARKYF 124 Score = 26.9 bits (58), Expect(2) = 3e-17 Identities = 11/17 (64%), Positives = 12/17 (70%) Frame = +2 Query: 506 QLISGVSYCHSMQVCHR 556 QLI+ V YCHS V HR Sbjct: 126 QLINAVDYCHSRGVYHR 142
>SNF1_SCHPO (O74536) SNF1-like protein kinase ssp2 (EC 2.7.11.1)| Length = 576 Score = 81.6 bits (200), Expect(2) = 4e-17 Identities = 47/105 (44%), Positives = 65/105 (61%), Gaps = 4/105 (3%) Frame = +3 Query: 201 YEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERG--HKIDEH--VQREIMNHRSLKHPN 368 Y + +G G+FG KL +T++ A+KFI R K D H V+REI + L+HP+ Sbjct: 34 YIIRETLGEGSFGKVKLATHYKTQQKVALKFISRQLLKKSDMHMRVEREISYLKLLRHPH 93 Query: 369 IIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFF 503 II+ +V+ TPT + +V+EYA GGELF I R +EDEGR FF Sbjct: 94 IIKLYDVITTPTDIVMVIEYA-GGELFDYIVEKKRMTEDEGRRFF 137 Score = 25.4 bits (54), Expect(2) = 4e-17 Identities = 8/23 (34%), Positives = 13/23 (56%) Frame = +2 Query: 488 GKVLLPQLISGVSYCHSMQVCHR 556 G+ Q+I + YCH ++ HR Sbjct: 133 GRRFFQQIICAIEYCHRHKIVHR 155
>CPK24_ARATH (Q9LDI3) CBL-interacting serine/threonine-protein kinase 24 (EC| 2.7.11.1) (SNF1-related kinase 3.11) (SALT OVERLY SENSITIVE 2 protein) Length = 446 Score = 83.2 bits (204), Expect(2) = 9e-17 Identities = 40/106 (37%), Positives = 66/106 (62%), Gaps = 4/106 (3%) Frame = +3 Query: 198 RYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERG----HKIDEHVQREIMNHRSLKHP 365 +YEV R IG G F K R+ T ++ A+K + + +++ + ++REI + ++HP Sbjct: 10 KYEVGRTIGEGTFAKVKFARNTDTGDNVAIKIMAKSTILKNRMVDQIKREISIMKIVRHP 69 Query: 366 NIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFF 503 NI+R EV+ +P+ + IV+E+ +GGELF RI + GR E E R +F Sbjct: 70 NIVRLYEVLASPSKIYIVLEFVTGGELFDRIVHKGRLEESESRKYF 115 Score = 22.7 bits (47), Expect(2) = 9e-17 Identities = 8/17 (47%), Positives = 11/17 (64%) Frame = +2 Query: 506 QLISGVSYCHSMQVCHR 556 QL+ V++CH V HR Sbjct: 117 QLVDAVAHCHCKGVYHR 133
>KIN11_ARATH (P92958) SNF1-related protein kinase catalytic alpha subunit KIN11| (EC 2.7.11.1) (AKIN11) (AKIN alpha1) Length = 512 Score = 76.3 bits (186), Expect(2) = 2e-16 Identities = 42/108 (38%), Positives = 60/108 (55%), Gaps = 4/108 (3%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIER----GHKIDEHVQREIMNHRSLK 359 + Y++ + +G G+FG K+ V T A+K + R +++E V+REI R Sbjct: 17 LPNYKLGKTLGIGSFGKVKIAEHVVTGHKVAIKILNRRKIKNMEMEEKVRREIKILRLFM 76 Query: 360 HPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFF 503 HP+IIR EV+ T + + +VMEY GELF I GR EDE R FF Sbjct: 77 HPHIIRQYEVIETTSDIYVVMEYVKSGELFDYIVEKGRLQEDEARNFF 124 Score = 28.5 bits (62), Expect(2) = 2e-16 Identities = 11/17 (64%), Positives = 12/17 (70%) Frame = +2 Query: 506 QLISGVSYCHSMQVCHR 556 Q+ISGV YCH V HR Sbjct: 126 QIISGVEYCHRNMVVHR 142
>AAPK1_PONPY (Q5RDH5) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMPK alpha-1 chain) Length = 550 Score = 72.8 bits (177), Expect(2) = 2e-15 Identities = 39/99 (39%), Positives = 55/99 (55%), Gaps = 4/99 (4%) Frame = +3 Query: 219 IGSGNFGVAKLVRDVRTREHFAVKFIERGH----KIDEHVQREIMNHRSLKHPNIIRFKE 386 +G G FG K+ + T AVK + R + ++REI N + +HP+II+ + Sbjct: 24 LGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQ 83 Query: 387 VVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFF 503 V+ TP+ + +VMEY SGGELF IC GR E E R F Sbjct: 84 VISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLF 122 Score = 28.9 bits (63), Expect(2) = 2e-15 Identities = 11/20 (55%), Positives = 13/20 (65%) Frame = +2 Query: 497 LLPQLISGVSYCHSMQVCHR 556 L Q++SGV YCH V HR Sbjct: 121 LFQQILSGVDYCHRHMVVHR 140
>AAPK1_HUMAN (Q13131) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMPK alpha-1 chain) Length = 550 Score = 72.8 bits (177), Expect(2) = 2e-15 Identities = 39/99 (39%), Positives = 55/99 (55%), Gaps = 4/99 (4%) Frame = +3 Query: 219 IGSGNFGVAKLVRDVRTREHFAVKFIERGH----KIDEHVQREIMNHRSLKHPNIIRFKE 386 +G G FG K+ + T AVK + R + ++REI N + +HP+II+ + Sbjct: 24 LGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQ 83 Query: 387 VVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFF 503 V+ TP+ + +VMEY SGGELF IC GR E E R F Sbjct: 84 VISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLF 122 Score = 28.9 bits (63), Expect(2) = 2e-15 Identities = 11/20 (55%), Positives = 13/20 (65%) Frame = +2 Query: 497 LLPQLISGVSYCHSMQVCHR 556 L Q++SGV YCH V HR Sbjct: 121 LFQQILSGVDYCHRHMVVHR 140
>AAPK1_RAT (P54645) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMPK alpha-1 chain) Length = 548 Score = 72.8 bits (177), Expect(2) = 2e-15 Identities = 39/99 (39%), Positives = 55/99 (55%), Gaps = 4/99 (4%) Frame = +3 Query: 219 IGSGNFGVAKLVRDVRTREHFAVKFIERGH----KIDEHVQREIMNHRSLKHPNIIRFKE 386 +G G FG K+ + T AVK + R + ++REI N + +HP+II+ + Sbjct: 22 LGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQ 81 Query: 387 VVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFF 503 V+ TP+ + +VMEY SGGELF IC GR E E R F Sbjct: 82 VISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLF 120 Score = 28.9 bits (63), Expect(2) = 2e-15 Identities = 11/20 (55%), Positives = 13/20 (65%) Frame = +2 Query: 497 LLPQLISGVSYCHSMQVCHR 556 L Q++SGV YCH V HR Sbjct: 119 LFQQILSGVDYCHRHMVVHR 138
>AAPK1_MOUSE (Q5EG47) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMPK alpha-1 chain) Length = 548 Score = 72.8 bits (177), Expect(2) = 2e-15 Identities = 39/99 (39%), Positives = 55/99 (55%), Gaps = 4/99 (4%) Frame = +3 Query: 219 IGSGNFGVAKLVRDVRTREHFAVKFIERGH----KIDEHVQREIMNHRSLKHPNIIRFKE 386 +G G FG K+ + T AVK + R + ++REI N + +HP+II+ + Sbjct: 22 LGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQ 81 Query: 387 VVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFF 503 V+ TP+ + +VMEY SGGELF IC GR E E R F Sbjct: 82 VISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLF 120 Score = 28.9 bits (63), Expect(2) = 2e-15 Identities = 11/20 (55%), Positives = 13/20 (65%) Frame = +2 Query: 497 LLPQLISGVSYCHSMQVCHR 556 L Q++SGV YCH V HR Sbjct: 119 LFQQILSGVDYCHRHMVVHR 138
>MARK4_MOUSE (Q8CIP4) MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1)| Length = 752 Score = 75.1 bits (183), Expect(2) = 3e-15 Identities = 41/104 (39%), Positives = 57/104 (54%), Gaps = 3/104 (2%) Frame = +3 Query: 201 YEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEHVQ---REIMNHRSLKHPNI 371 Y ++R IG GNF KL R + T A+K I++ +Q RE+ + L HPNI Sbjct: 59 YRLLRTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPSSLQKLFREVRIMKGLNHPNI 118 Query: 372 IRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFF 503 ++ EV+ T L +VMEYAS GE+F + + GR E E R F Sbjct: 119 VKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKF 162 Score = 25.8 bits (55), Expect(2) = 3e-15 Identities = 8/17 (47%), Positives = 11/17 (64%) Frame = +2 Query: 506 QLISGVSYCHSMQVCHR 556 Q++S V YCH + HR Sbjct: 164 QIVSAVHYCHQKNIVHR 180
>MARK4_HUMAN (Q96L34) MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase-like 1) Length = 752 Score = 75.1 bits (183), Expect(2) = 3e-15 Identities = 41/104 (39%), Positives = 57/104 (54%), Gaps = 3/104 (2%) Frame = +3 Query: 201 YEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEHVQ---REIMNHRSLKHPNI 371 Y ++R IG GNF KL R + T A+K I++ +Q RE+ + L HPNI Sbjct: 59 YRLLRTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPSSLQKLFREVRIMKGLNHPNI 118 Query: 372 IRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFF 503 ++ EV+ T L +VMEYAS GE+F + + GR E E R F Sbjct: 119 VKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKF 162 Score = 25.8 bits (55), Expect(2) = 3e-15 Identities = 8/17 (47%), Positives = 11/17 (64%) Frame = +2 Query: 506 QLISGVSYCHSMQVCHR 556 Q++S V YCH + HR Sbjct: 164 QIVSAVHYCHQKNIVHR 180
>MARK2_HUMAN (Q7KZI7) Serine/threonine-protein kinase MARK2 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 2) (ELKL motif kinase) (EMK1) (PAR1 homolog) Length = 788 Score = 75.5 bits (184), Expect(2) = 4e-15 Identities = 42/104 (40%), Positives = 58/104 (55%), Gaps = 3/104 (2%) Frame = +3 Query: 201 YEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEHVQ---REIMNHRSLKHPNI 371 Y +++ IG GNF KL R + T + AVK I++ +Q RE+ + L HPNI Sbjct: 53 YRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNI 112 Query: 372 IRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFF 503 ++ EV+ T L +VMEYASGGE+F + GR E E R F Sbjct: 113 VKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKF 156 Score = 25.0 bits (53), Expect(2) = 4e-15 Identities = 8/17 (47%), Positives = 11/17 (64%) Frame = +2 Query: 506 QLISGVSYCHSMQVCHR 556 Q++S V YCH + HR Sbjct: 158 QIVSAVQYCHQKFIVHR 174
>MARK2_RAT (O08679) Serine/threonine-protein kinase MARK2 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 2) (ELKL Motif Kinase) (EMK1) Length = 722 Score = 75.5 bits (184), Expect(2) = 4e-15 Identities = 42/104 (40%), Positives = 58/104 (55%), Gaps = 3/104 (2%) Frame = +3 Query: 201 YEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEHVQ---REIMNHRSLKHPNI 371 Y +++ IG GNF KL R + T + AVK I++ +Q RE+ + L HPNI Sbjct: 53 YRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNI 112 Query: 372 IRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFF 503 ++ EV+ T L +VMEYASGGE+F + GR E E R F Sbjct: 113 VKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKF 156 Score = 25.0 bits (53), Expect(2) = 4e-15 Identities = 8/17 (47%), Positives = 11/17 (64%) Frame = +2 Query: 506 QLISGVSYCHSMQVCHR 556 Q++S V YCH + HR Sbjct: 158 QIVSAVQYCHQKFIVHR 174
>MARK3_RAT (Q8VHF0) MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1)| Length = 797 Score = 73.6 bits (179), Expect(2) = 5e-15 Identities = 40/104 (38%), Positives = 57/104 (54%), Gaps = 3/104 (2%) Frame = +3 Query: 201 YEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEHVQ---REIMNHRSLKHPNI 371 Y +++ IG GNF KL R + T A+K I++ +Q RE+ + L HPNI Sbjct: 56 YRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNI 115 Query: 372 IRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFF 503 ++ EV+ T L ++MEYASGGE+F + GR E E R F Sbjct: 116 VKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARAKF 159 Score = 26.6 bits (57), Expect(2) = 5e-15 Identities = 8/17 (47%), Positives = 12/17 (70%) Frame = +2 Query: 506 QLISGVSYCHSMQVCHR 556 Q++S V YCH ++ HR Sbjct: 161 QIVSAVQYCHQKRIVHR 177
>MARK3_MOUSE (Q03141) MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1)| (MPK-10) (ELKL motif kinase 2) Length = 753 Score = 73.6 bits (179), Expect(2) = 5e-15 Identities = 40/104 (38%), Positives = 57/104 (54%), Gaps = 3/104 (2%) Frame = +3 Query: 201 YEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEHVQ---REIMNHRSLKHPNI 371 Y +++ IG GNF KL R + T A+K I++ +Q RE+ + L HPNI Sbjct: 56 YRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNI 115 Query: 372 IRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFF 503 ++ EV+ T L ++MEYASGGE+F + GR E E R F Sbjct: 116 VKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARAKF 159 Score = 26.6 bits (57), Expect(2) = 5e-15 Identities = 8/17 (47%), Positives = 12/17 (70%) Frame = +2 Query: 506 QLISGVSYCHSMQVCHR 556 Q++S V YCH ++ HR Sbjct: 161 QIVSAVQYCHQKRIVHR 177
>MARK1_HUMAN (Q9P0L2) Serine/threonine-protein kinase MARK1 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 1) Length = 795 Score = 73.6 bits (179), Expect(2) = 8e-15 Identities = 43/104 (41%), Positives = 56/104 (53%), Gaps = 3/104 (2%) Frame = +3 Query: 201 YEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEHVQ---REIMNHRSLKHPNI 371 Y + + IG GNF KL R V T AVK I++ +Q RE+ + L HPNI Sbjct: 60 YRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMKILNHPNI 119 Query: 372 IRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFF 503 ++ EV+ T L +VMEYASGGE+F + GR E E R F Sbjct: 120 VKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKF 163 Score = 25.8 bits (55), Expect(2) = 8e-15 Identities = 8/17 (47%), Positives = 11/17 (64%) Frame = +2 Query: 506 QLISGVSYCHSMQVCHR 556 Q++S V YCH + HR Sbjct: 165 QIVSAVQYCHQKYIVHR 181
>CPK15_ARATH (P92937) CBL-interacting serine/threonine-protein kinase 15 (EC| 2.7.11.1) (Serine/threonine-protein kinase ATPK10) (SOS2-like protein kinase PKS3) (SOS-interacting protein 2) (SNF1-related kinase 3.1) Length = 421 Score = 70.9 bits (172), Expect(2) = 8e-15 Identities = 39/108 (36%), Positives = 61/108 (56%), Gaps = 4/108 (3%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKID----EHVQREIMNHRSLK 359 M RYEV + +G G F R ++T + A+K I++ + E ++REI R L+ Sbjct: 9 MLRYEVGKFLGQGTFAKVYHARHLKTGDSVAIKVIDKERILKVGMTEQIKREISAMRLLR 68 Query: 360 HPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFF 503 HPNI+ EV+ T + + VME+ GGELF ++ + G+ ED R +F Sbjct: 69 HPNIVELHEVMATKSKIYFVMEHVKGGELFNKV-STGKLREDVARKYF 115 Score = 28.5 bits (62), Expect(2) = 8e-15 Identities = 10/17 (58%), Positives = 12/17 (70%) Frame = +2 Query: 506 QLISGVSYCHSMQVCHR 556 QL+ V +CHS VCHR Sbjct: 117 QLVRAVDFCHSRGVCHR 133
>MARK1_MOUSE (Q8VHJ5) Serine/threonine-protein kinase MARK1 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 1) (ELKL motif serine/threonine-protein kinase 3) Length = 795 Score = 73.6 bits (179), Expect(2) = 1e-14 Identities = 43/104 (41%), Positives = 56/104 (53%), Gaps = 3/104 (2%) Frame = +3 Query: 201 YEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEHVQ---REIMNHRSLKHPNI 371 Y + + IG GNF KL R V T AVK I++ +Q RE+ + L HPNI Sbjct: 60 YRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMKILNHPNI 119 Query: 372 IRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFF 503 ++ EV+ T L +VMEYASGGE+F + GR E E R F Sbjct: 120 VKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKF 163 Score = 25.0 bits (53), Expect(2) = 1e-14 Identities = 8/17 (47%), Positives = 11/17 (64%) Frame = +2 Query: 506 QLISGVSYCHSMQVCHR 556 Q++S V YCH + HR Sbjct: 165 QIVSAVQYCHQKCIVHR 181
>MARK1_RAT (O08678) Serine/threonine-protein kinase MARK1 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 1) Length = 793 Score = 73.6 bits (179), Expect(2) = 1e-14 Identities = 43/104 (41%), Positives = 56/104 (53%), Gaps = 3/104 (2%) Frame = +3 Query: 201 YEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEHVQ---REIMNHRSLKHPNI 371 Y + + IG GNF KL R V T AVK I++ +Q RE+ + L HPNI Sbjct: 60 YRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMKILNHPNI 119 Query: 372 IRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFF 503 ++ EV+ T L +VMEYASGGE+F + GR E E R F Sbjct: 120 VKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKF 163 Score = 25.0 bits (53), Expect(2) = 1e-14 Identities = 8/17 (47%), Positives = 11/17 (64%) Frame = +2 Query: 506 QLISGVSYCHSMQVCHR 556 Q++S V YCH + HR Sbjct: 165 QIVSAVQYCHQKCIVHR 181
>AAPK2_RAT (Q09137) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMPK alpha-2 chain) Length = 552 Score = 72.0 bits (175), Expect(2) = 1e-14 Identities = 40/99 (40%), Positives = 53/99 (53%), Gaps = 4/99 (4%) Frame = +3 Query: 219 IGSGNFGVAKLVRDVRTREHFAVKFIERGH----KIDEHVQREIMNHRSLKHPNIIRFKE 386 +G G FG K+ T AVK + R + ++REI N + +HP+II+ + Sbjct: 22 LGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPHIIKLYQ 81 Query: 387 VVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFF 503 V+ TPT +VMEY SGGELF IC GR E E R F Sbjct: 82 VISTPTDFFMVMEYVSGGELFDYICKHGRVEEVEARRLF 120 Score = 26.6 bits (57), Expect(2) = 1e-14 Identities = 10/20 (50%), Positives = 12/20 (60%) Frame = +2 Query: 497 LLPQLISGVSYCHSMQVCHR 556 L Q++S V YCH V HR Sbjct: 119 LFQQILSAVDYCHRHMVVHR 138
>AAPK2_PONPY (Q5RD00) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMPK alpha-2 chain) Length = 552 Score = 72.0 bits (175), Expect(2) = 1e-14 Identities = 40/99 (40%), Positives = 53/99 (53%), Gaps = 4/99 (4%) Frame = +3 Query: 219 IGSGNFGVAKLVRDVRTREHFAVKFIERGH----KIDEHVQREIMNHRSLKHPNIIRFKE 386 +G G FG K+ T AVK + R + ++REI N + +HP+II+ + Sbjct: 22 LGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPHIIKLYQ 81 Query: 387 VVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFF 503 V+ TPT +VMEY SGGELF IC GR E E R F Sbjct: 82 VISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLF 120 Score = 26.6 bits (57), Expect(2) = 1e-14 Identities = 10/20 (50%), Positives = 12/20 (60%) Frame = +2 Query: 497 LLPQLISGVSYCHSMQVCHR 556 L Q++S V YCH V HR Sbjct: 119 LFQQILSAVDYCHRHMVVHR 138
>AAPK2_PIG (Q28948) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMPK alpha-2 chain) Length = 552 Score = 72.0 bits (175), Expect(2) = 1e-14 Identities = 40/99 (40%), Positives = 53/99 (53%), Gaps = 4/99 (4%) Frame = +3 Query: 219 IGSGNFGVAKLVRDVRTREHFAVKFIERGH----KIDEHVQREIMNHRSLKHPNIIRFKE 386 +G G FG K+ T AVK + R + ++REI N + +HP+II+ + Sbjct: 22 LGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPHIIKLYQ 81 Query: 387 VVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFF 503 V+ TPT +VMEY SGGELF IC GR E E R F Sbjct: 82 VISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLF 120 Score = 26.6 bits (57), Expect(2) = 1e-14 Identities = 10/20 (50%), Positives = 12/20 (60%) Frame = +2 Query: 497 LLPQLISGVSYCHSMQVCHR 556 L Q++S V YCH V HR Sbjct: 119 LFQQILSAVDYCHRHMVVHR 138
>AAPK2_HUMAN (P54646) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMPK alpha-2 chain) Length = 552 Score = 72.0 bits (175), Expect(2) = 1e-14 Identities = 40/99 (40%), Positives = 53/99 (53%), Gaps = 4/99 (4%) Frame = +3 Query: 219 IGSGNFGVAKLVRDVRTREHFAVKFIERGH----KIDEHVQREIMNHRSLKHPNIIRFKE 386 +G G FG K+ T AVK + R + ++REI N + +HP+II+ + Sbjct: 22 LGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPHIIKLYQ 81 Query: 387 VVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFF 503 V+ TPT +VMEY SGGELF IC GR E E R F Sbjct: 82 VISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLF 120 Score = 26.6 bits (57), Expect(2) = 1e-14 Identities = 10/20 (50%), Positives = 12/20 (60%) Frame = +2 Query: 497 LLPQLISGVSYCHSMQVCHR 556 L Q++S V YCH V HR Sbjct: 119 LFQQILSAVDYCHRHMVVHR 138
>MARK3_HUMAN (P27448) MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1)| (Cdc25C-associated protein kinase 1) (cTAK1) (C-TAK1) (Serine/threonine protein kinase p78) (Ser/Thr protein kinase PAR-1) (Protein kinase STK10) Length = 776 Score = 73.6 bits (179), Expect(2) = 2e-14 Identities = 40/104 (38%), Positives = 57/104 (54%), Gaps = 3/104 (2%) Frame = +3 Query: 201 YEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEHVQ---REIMNHRSLKHPNI 371 Y +++ IG GNF KL R + T A+K I++ +Q RE+ + L HPNI Sbjct: 56 YRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNI 115 Query: 372 IRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFF 503 ++ EV+ T L ++MEYASGGE+F + GR E E R F Sbjct: 116 VKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKF 159 Score = 24.6 bits (52), Expect(2) = 2e-14 Identities = 7/16 (43%), Positives = 11/16 (68%) Frame = +2 Query: 509 LISGVSYCHSMQVCHR 556 ++S V YCH ++ HR Sbjct: 185 IVSAVQYCHQKRIVHR 200
>CPK11_ARATH (O22932) CBL-interacting serine/threonine-protein kinase 11 (EC| 2.7.11.1) (SOS2-like protein kinase PKS5) (SOS-interacting protein 4) (SNF1-related kinase 3.22) Length = 435 Score = 71.2 bits (173), Expect(2) = 2e-14 Identities = 39/107 (36%), Positives = 58/107 (54%), Gaps = 5/107 (4%) Frame = +3 Query: 198 RYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIER-----GHKIDEHVQREIMNHRSLKH 362 +YE+ + +G G F RD RT + AVK + + + +++REI R L H Sbjct: 20 KYELGKLLGCGAFAKVFHARDRRTGQSVAVKILNKKKLLTNPALANNIKREISIMRRLSH 79 Query: 363 PNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFF 503 PNI++ EV+ T + + ME+ GGELF +I GR SED R +F Sbjct: 80 PNIVKLHEVMATKSKIFFAMEFVKGGELFNKISKHGRLSEDLSRRYF 126 Score = 26.9 bits (58), Expect(2) = 2e-14 Identities = 11/17 (64%), Positives = 12/17 (70%) Frame = +2 Query: 506 QLISGVSYCHSMQVCHR 556 QLIS V YCH+ V HR Sbjct: 128 QLISAVGYCHARGVYHR 144
>SN1L2_MOUSE (Q8CFH6) Serine/threonine-protein kinase SNF1-like kinase 2 (EC| 2.7.11.1) (Salt-inducible kinase 2) Length = 931 Score = 70.9 bits (172), Expect(2) = 3e-14 Identities = 38/102 (37%), Positives = 59/102 (57%), Gaps = 4/102 (3%) Frame = +3 Query: 201 YEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKID----EHVQREIMNHRSLKHPN 368 Y++ +G GNF V KL R T+ A+K I++ ++D E + RE+ + L HP+ Sbjct: 20 YDIEGTLGKGNFAVVKLGRHRTTKTEVAIKIIDKS-QLDAVNLEKIYREVQIMKMLDHPH 78 Query: 369 IIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGR 494 II+ +V+ T + L +V EYA GE+F + N GR +E E R Sbjct: 79 IIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEAR 120 Score = 26.6 bits (57), Expect(2) = 3e-14 Identities = 9/17 (52%), Positives = 12/17 (70%) Frame = +2 Query: 506 QLISGVSYCHSMQVCHR 556 Q++S V YCH +V HR Sbjct: 125 QILSAVDYCHGRKVVHR 141
>SN1L1_MOUSE (Q60670) Serine/threonine-protein kinase SNF1-like kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase SNF1LK) (HRT-20) (Myocardial SNF1-like kinase) Length = 779 Score = 71.6 bits (174), Expect(2) = 3e-14 Identities = 40/102 (39%), Positives = 59/102 (57%), Gaps = 4/102 (3%) Frame = +3 Query: 201 YEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKID----EHVQREIMNHRSLKHPN 368 Y+V R +G GNF V KL R T+ A+K I++ ++D E + RE+ + L HPN Sbjct: 27 YDVERTLGKGNFAVVKLARHRVTKTQVAIKIIDKT-RLDSSNLEKIYREVQLMKLLNHPN 85 Query: 369 IIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGR 494 II+ +V+ T L IV E+A GE+F + + G SE+E R Sbjct: 86 IIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEAR 127 Score = 25.8 bits (55), Expect(2) = 3e-14 Identities = 8/17 (47%), Positives = 12/17 (70%) Frame = +2 Query: 506 QLISGVSYCHSMQVCHR 556 Q++S V YCH+ + HR Sbjct: 132 QILSAVEYCHNHHIVHR 148
>MARK2_MOUSE (Q05512) Serine/threonine-protein kinase MARK2 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 2) (ELKL Motif Kinase) (EMK1) Length = 776 Score = 75.5 bits (184), Expect(2) = 3e-14 Identities = 42/104 (40%), Positives = 58/104 (55%), Gaps = 3/104 (2%) Frame = +3 Query: 201 YEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEHVQ---REIMNHRSLKHPNI 371 Y +++ IG GNF KL R + T + AVK I++ +Q RE+ + L HPNI Sbjct: 53 YRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNI 112 Query: 372 IRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFF 503 ++ EV+ T L +VMEYASGGE+F + GR E E R F Sbjct: 113 VKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKF 156 Score = 21.9 bits (45), Expect(2) = 3e-14 Identities = 7/17 (41%), Positives = 10/17 (58%) Frame = +2 Query: 506 QLISGVSYCHSMQVCHR 556 Q++ V YCH + HR Sbjct: 158 QIVLHVQYCHQKFIVHR 174
>SN1L1_RAT (Q9R1U5) Serine/threonine-protein kinase SNF1-like kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase SNF1LK) (Salt-inducible protein kinase) (Protein kinase KID2) Length = 776 Score = 71.6 bits (174), Expect(2) = 3e-14 Identities = 40/102 (39%), Positives = 59/102 (57%), Gaps = 4/102 (3%) Frame = +3 Query: 201 YEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKID----EHVQREIMNHRSLKHPN 368 Y+V R +G GNF V KL R T+ A+K I++ ++D E + RE+ + L HPN Sbjct: 27 YDVERTLGKGNFAVVKLARHRVTKTQVAIKIIDKT-RLDSSNLEKIYREVQLMKLLNHPN 85 Query: 369 IIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGR 494 II+ +V+ T L IV E+A GE+F + + G SE+E R Sbjct: 86 IIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEAR 127 Score = 25.8 bits (55), Expect(2) = 3e-14 Identities = 8/17 (47%), Positives = 12/17 (70%) Frame = +2 Query: 506 QLISGVSYCHSMQVCHR 556 Q++S V YCH+ + HR Sbjct: 132 QILSAVEYCHNHHIVHR 148
>SNF1_CANTR (O94168) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 619 Score = 72.0 bits (175), Expect(2) = 4e-14 Identities = 40/106 (37%), Positives = 62/106 (58%), Gaps = 4/106 (3%) Frame = +3 Query: 198 RYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIER----GHKIDEHVQREIMNHRSLKHP 365 RY++++ +G G+FG KL + V T + A+K I R + V+REI R L+HP Sbjct: 51 RYQIIKTLGEGSFGKVKLAQHVGTGQKVALKIINRKTLAKSDMQGRVEREISYLRLLRHP 110 Query: 366 NIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFF 503 +II+ +V+ + + +V+E+A G ELF I G+ EDE R FF Sbjct: 111 HIIKLYDVIKSKDEIIMVIEFA-GKELFDYIVQRGKMPEDEARRFF 155 Score = 25.0 bits (53), Expect(2) = 4e-14 Identities = 8/17 (47%), Positives = 12/17 (70%) Frame = +2 Query: 506 QLISGVSYCHSMQVCHR 556 Q+I+ V YCH ++ HR Sbjct: 157 QIIAAVEYCHRHKIVHR 173
>SN1L2_CHICK (Q9IA88) Serine/threonine-protein kinase SNF1-like kinase 2 (EC| 2.7.11.1) (Qin-induced kinase) Length = 798 Score = 69.7 bits (169), Expect(2) = 5e-14 Identities = 38/102 (37%), Positives = 58/102 (56%), Gaps = 4/102 (3%) Frame = +3 Query: 201 YEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKID----EHVQREIMNHRSLKHPN 368 Y++ R +G GNF V KL R T+ A+K I++ ++D E + RE+ + L HP+ Sbjct: 26 YDIERTLGKGNFAVVKLARHRVTKTQVAIKIIDKT-RLDPSNLEKIYREVQIMKLLNHPH 84 Query: 369 IIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGR 494 II+ +V+ T L IV E+A GE+F + + G SE E R Sbjct: 85 IIKLYQVMETKDMLYIVTEFAKNGEMFDHLTSNGHLSESEAR 126 Score = 26.9 bits (58), Expect(2) = 5e-14 Identities = 9/17 (52%), Positives = 12/17 (70%) Frame = +2 Query: 506 QLISGVSYCHSMQVCHR 556 Q++S V YCHS + HR Sbjct: 131 QILSAVEYCHSHHIVHR 147
>SN1L2_HUMAN (Q9H0K1) Serine/threonine-protein kinase SNF1-like kinase 2 (EC| 2.7.11.1) (Qin-induced kinase) Length = 926 Score = 70.1 bits (170), Expect(2) = 6e-14 Identities = 38/102 (37%), Positives = 59/102 (57%), Gaps = 4/102 (3%) Frame = +3 Query: 201 YEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKID----EHVQREIMNHRSLKHPN 368 Y++ +G GNF V KL R T+ A+K I++ ++D E + RE+ + L HP+ Sbjct: 20 YDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKS-QLDAVNLEKIYREVQIMKMLDHPH 78 Query: 369 IIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGR 494 II+ +V+ T + L +V EYA GE+F + N GR +E E R Sbjct: 79 IIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEAR 120 Score = 26.2 bits (56), Expect(2) = 6e-14 Identities = 8/17 (47%), Positives = 12/17 (70%) Frame = +2 Query: 506 QLISGVSYCHSMQVCHR 556 Q++S V YCH ++ HR Sbjct: 125 QILSAVDYCHGRKIVHR 141
>SN1L2_PONPY (Q5REX1) Serine/threonine-protein kinase SNF1-like kinase 2 (EC| 2.7.11.1) Length = 925 Score = 70.1 bits (170), Expect(2) = 6e-14 Identities = 38/102 (37%), Positives = 59/102 (57%), Gaps = 4/102 (3%) Frame = +3 Query: 201 YEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKID----EHVQREIMNHRSLKHPN 368 Y++ +G GNF V KL R T+ A+K I++ ++D E + RE+ + L HP+ Sbjct: 20 YDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKS-QLDAVNLEKIYREVQIMKMLDHPH 78 Query: 369 IIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGR 494 II+ +V+ T + L +V EYA GE+F + N GR +E E R Sbjct: 79 IIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEAR 120 Score = 26.2 bits (56), Expect(2) = 6e-14 Identities = 8/17 (47%), Positives = 12/17 (70%) Frame = +2 Query: 506 QLISGVSYCHSMQVCHR 556 Q++S V YCH ++ HR Sbjct: 125 QILSAVDYCHGRKIVHR 141
>SNF1_CANAL (P52497) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 620 Score = 70.1 bits (170), Expect(2) = 1e-13 Identities = 39/106 (36%), Positives = 62/106 (58%), Gaps = 4/106 (3%) Frame = +3 Query: 198 RYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIER----GHKIDEHVQREIMNHRSLKHP 365 RY++++ +G G+FG KL + + T + A+K I R + V+REI R L+HP Sbjct: 52 RYQILKTLGEGSFGKVKLAQHLGTGQKVALKIINRKTLAKSDMQGRVEREISYLRLLRHP 111 Query: 366 NIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFF 503 +II+ +V+ + + +V+E+A G ELF I G+ EDE R FF Sbjct: 112 HIIKLYDVIKSKDEIIMVIEFA-GKELFDYIVQRGKMPEDEARRFF 156 Score = 25.0 bits (53), Expect(2) = 1e-13 Identities = 8/17 (47%), Positives = 12/17 (70%) Frame = +2 Query: 506 QLISGVSYCHSMQVCHR 556 Q+I+ V YCH ++ HR Sbjct: 158 QIIAAVEYCHRHKIVHR 174
>SN1L1_HUMAN (P57059) Serine/threonine-protein kinase SNF1-like kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase SNF1LK) Length = 783 Score = 69.3 bits (168), Expect(2) = 2e-13 Identities = 38/102 (37%), Positives = 59/102 (57%), Gaps = 4/102 (3%) Frame = +3 Query: 201 YEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKID----EHVQREIMNHRSLKHPN 368 Y++ R +G GNF V KL R T+ A+K I++ ++D E + RE+ + L HP+ Sbjct: 27 YDIERTLGKGNFAVVKLARHRVTKTQVAIKIIDKT-RLDSSNLEKIYREVQLMKLLNHPH 85 Query: 369 IIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGR 494 II+ +V+ T L IV E+A GE+F + + G SE+E R Sbjct: 86 IIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEAR 127 Score = 25.4 bits (54), Expect(2) = 2e-13 Identities = 8/17 (47%), Positives = 11/17 (64%) Frame = +2 Query: 506 QLISGVSYCHSMQVCHR 556 Q++S V YCH + HR Sbjct: 132 QILSAVEYCHDHHIVHR 148
>AAPK2_CAEEL (Q95ZQ4) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMP-activated kinase 2) Length = 626 Score = 66.2 bits (160), Expect(2) = 2e-13 Identities = 40/106 (37%), Positives = 56/106 (52%), Gaps = 5/106 (4%) Frame = +3 Query: 201 YEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDE-----HVQREIMNHRSLKHP 365 Y + +G G FG K+ T+ AVK + R KI ++REI N +HP Sbjct: 87 YILKETLGVGTFGKVKVGIHETTQYKVAVKILNR-QKIKSLDVVGKIRREIQNLSLFRHP 145 Query: 366 NIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFF 503 +IIR +V+ TP+ + ++ME+ SGGELF I GR E R FF Sbjct: 146 HIIRLYQVISTPSDIFMIMEHVSGGELFDYIVKHGRLKTAEARRFF 191 Score = 28.5 bits (62), Expect(2) = 2e-13 Identities = 11/17 (64%), Positives = 12/17 (70%) Frame = +2 Query: 506 QLISGVSYCHSMQVCHR 556 Q+ISGV YCH V HR Sbjct: 193 QIISGVDYCHRHMVVHR 209
>SNF1_CANGA (Q00372) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 612 Score = 67.8 bits (164), Expect(2) = 3e-13 Identities = 38/105 (36%), Positives = 59/105 (56%), Gaps = 4/105 (3%) Frame = +3 Query: 201 YEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERG----HKIDEHVQREIMNHRSLKHPN 368 Y++V+ +G G+FG KL V T + A+K I + + ++REI R L+HP+ Sbjct: 39 YQIVKTLGEGSFGKVKLAYHVTTGQKVALKIINKKVLAKSDMQGRIEREISYLRLLRHPH 98 Query: 369 IIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFF 503 II+ +V+ + + +V+EYA G ELF I + SE E R FF Sbjct: 99 IIKLYDVIKSKDEIIMVIEYA-GNELFDYIVQRNKMSEQEARRFF 142 Score = 26.2 bits (56), Expect(2) = 3e-13 Identities = 9/17 (52%), Positives = 12/17 (70%) Frame = +2 Query: 506 QLISGVSYCHSMQVCHR 556 Q+IS V YCH ++ HR Sbjct: 144 QIISAVEYCHRHKIVHR 160
>DCAK1_MOUSE (Q9JLM8) Serine/threonine-protein kinase DCAMKL1 (EC 2.7.11.1)| (Doublecortin-like and CAM kinase-like 1) Length = 756 Score = 70.1 bits (170), Expect(2) = 5e-13 Identities = 39/107 (36%), Positives = 60/107 (56%), Gaps = 2/107 (1%) Frame = +3 Query: 195 DRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGH-KIDEH-VQREIMNHRSLKHPN 368 +RY+V R IG GNF V K + T +A+K I++ + EH +Q E+ R +KHPN Sbjct: 404 ERYKVGRTIGDGNFAVVKECIERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRVKHPN 463 Query: 369 IIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFFHN 509 I+ E + PT L +VME GG+LF I + +++E + +N Sbjct: 464 IVLLIEEMDVPTELYLVMELVKGGDLFDAITSTSKYTERDASGMLYN 510 Score = 23.1 bits (48), Expect(2) = 5e-13 Identities = 8/20 (40%), Positives = 12/20 (60%) Frame = +2 Query: 497 LLPQLISGVSYCHSMQVCHR 556 +L L S + Y HS+ + HR Sbjct: 507 MLYNLASAIKYLHSLNIVHR 526
>DCAK1_HUMAN (O15075) Serine/threonine-protein kinase DCAMKL1 (EC 2.7.11.1)| (Doublecortin-like and CAM kinase-like 1) Length = 740 Score = 70.1 bits (170), Expect(2) = 5e-13 Identities = 39/107 (36%), Positives = 60/107 (56%), Gaps = 2/107 (1%) Frame = +3 Query: 195 DRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGH-KIDEH-VQREIMNHRSLKHPN 368 +RY+V R IG GNF V K + T +A+K I++ + EH +Q E+ R +KHPN Sbjct: 388 ERYKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRVKHPN 447 Query: 369 IIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFFHN 509 I+ E + PT L +VME GG+LF I + +++E + +N Sbjct: 448 IVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYN 494 Score = 23.1 bits (48), Expect(2) = 5e-13 Identities = 8/20 (40%), Positives = 12/20 (60%) Frame = +2 Query: 497 LLPQLISGVSYCHSMQVCHR 556 +L L S + Y HS+ + HR Sbjct: 491 MLYNLASAIKYLHSLNIVHR 510
>DCAK1_RAT (O08875) Serine/threonine-protein kinase DCAMKL1 (EC 2.7.11.1)| (Doublecortin-like and CAM kinase-like 1) (Calcium/calmodulin-dependent protein kinase type I-like CPG16) Length = 433 Score = 70.1 bits (170), Expect(2) = 5e-13 Identities = 39/107 (36%), Positives = 60/107 (56%), Gaps = 2/107 (1%) Frame = +3 Query: 195 DRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGH-KIDEH-VQREIMNHRSLKHPN 368 +RY+V R IG GNF V K + T +A+K I++ + EH +Q E+ R +KHPN Sbjct: 81 ERYKVGRTIGDGNFAVVKECIERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRVKHPN 140 Query: 369 IIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFFHN 509 I+ E + PT L +VME GG+LF I + +++E + +N Sbjct: 141 IVLLIEEMDVPTELYLVMELVKGGDLFDAITSTSKYTERDASGMLYN 187 Score = 23.1 bits (48), Expect(2) = 5e-13 Identities = 8/20 (40%), Positives = 12/20 (60%) Frame = +2 Query: 497 LLPQLISGVSYCHSMQVCHR 556 +L L S + Y HS+ + HR Sbjct: 184 MLYNLASAIKYLHSLNIVHR 203
>SNF1_YEAST (P06782) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 633 Score = 65.9 bits (159), Expect(2) = 1e-12 Identities = 37/105 (35%), Positives = 58/105 (55%), Gaps = 4/105 (3%) Frame = +3 Query: 201 YEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERG----HKIDEHVQREIMNHRSLKHPN 368 Y++V+ +G G+FG KL T + A+K I + + ++REI R L+HP+ Sbjct: 55 YQIVKTLGEGSFGKVKLAYHTTTGQKVALKIINKKVLAKSDMQGRIEREISYLRLLRHPH 114 Query: 369 IIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFF 503 II+ +V+ + + +V+EYA G ELF I + SE E R FF Sbjct: 115 IIKLYDVIKSKDEIIMVIEYA-GNELFDYIVQRDKMSEQEARRFF 158 Score = 26.2 bits (56), Expect(2) = 1e-12 Identities = 9/17 (52%), Positives = 12/17 (70%) Frame = +2 Query: 506 QLISGVSYCHSMQVCHR 556 Q+IS V YCH ++ HR Sbjct: 160 QIISAVEYCHRHKIVHR 176
>MYLK_DICDI (P25323) Myosin light chain kinase (EC 2.7.11.18) (MLCK)| Length = 295 Score = 68.6 bits (166), Expect(2) = 1e-12 Identities = 35/97 (36%), Positives = 57/97 (58%), Gaps = 3/97 (3%) Frame = +3 Query: 201 YEVVRDIGSGNFGVAKLVRDVRTREHFAVKFI---ERGHKIDEHVQREIMNHRSLKHPNI 371 YE ++G G F + L + +T++ +A+K I E G +++++ E+ + + HPNI Sbjct: 8 YEFKEELGRGAFSIVYLGENKQTKQRYAIKVINKSELGKDYEKNLKMEVDILKKVNHPNI 67 Query: 372 IRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSE 482 I KE+ TP L +VME +GGELF +I G +SE Sbjct: 68 IALKELFDTPEKLYLVMELVTGGELFDKIVEKGSYSE 104 Score = 23.5 bits (49), Expect(2) = 1e-12 Identities = 7/20 (35%), Positives = 13/20 (65%) Frame = +2 Query: 497 LLPQLISGVSYCHSMQVCHR 556 L+ +++S V Y H + + HR Sbjct: 110 LVKKIVSAVGYLHGLNIVHR 129
>DCAK2_MOUSE (Q6PGN3) Serine/threonine-protein kinase DCAMKL2 (EC 2.7.11.1)| (Doublecortin-like and CAM kinase-like 2) Length = 756 Score = 69.7 bits (169), Expect(2) = 1e-12 Identities = 39/108 (36%), Positives = 62/108 (57%), Gaps = 2/108 (1%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKID-EH-VQREIMNHRSLKHP 365 +++Y + + IG GNF V K D T + FA+K I++ EH ++ E+ R +KHP Sbjct: 390 LEKYRIGKVIGDGNFAVVKECVDRYTGKEFALKIIDKAKCCGKEHLIENEVSILRRVKHP 449 Query: 366 NIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFFHN 509 NII E + T T L +VME GG+LF I ++ +++E +G +N Sbjct: 450 NIIMLVEEMETATDLFLVMELVKGGDLFDAITSSTKYTERDGSAMVYN 497 Score = 21.9 bits (45), Expect(2) = 1e-12 Identities = 7/23 (30%), Positives = 13/23 (56%) Frame = +2 Query: 488 GKVLLPQLISGVSYCHSMQVCHR 556 G ++ L + + Y HS+ + HR Sbjct: 491 GSAMVYNLANALRYLHSLSIVHR 513
>NUAK1_HUMAN (O60285) NUAK family, SNF1-like kinase 1 (EC 2.7.11.1)| (AMPK-related protein kinase 5) Length = 661 Score = 66.6 bits (161), Expect(2) = 1e-12 Identities = 41/106 (38%), Positives = 54/106 (50%), Gaps = 4/106 (3%) Frame = +3 Query: 198 RYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDE----HVQREIMNHRSLKHP 365 RYE+ +G G +G K + + A+K I + DE H++REI SL HP Sbjct: 54 RYELQETLGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDEQDMVHIRREIEIMSSLNHP 113 Query: 366 NIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFF 503 +II EV + I+MEYAS GEL+ I R SE E R FF Sbjct: 114 HIISIYEVFENKDKIVIIMEYASKGELYDYISERRRLSERETRHFF 159 Score = 25.0 bits (53), Expect(2) = 1e-12 Identities = 9/17 (52%), Positives = 11/17 (64%) Frame = +2 Query: 506 QLISGVSYCHSMQVCHR 556 Q++S V YCH V HR Sbjct: 161 QIVSAVHYCHKNGVVHR 177
>NUAK1_MOUSE (Q641K5) NUAK family, SNF1-like kinase 1 (EC 2.7.11.1)| Length = 658 Score = 66.6 bits (161), Expect(2) = 1e-12 Identities = 41/106 (38%), Positives = 54/106 (50%), Gaps = 4/106 (3%) Frame = +3 Query: 198 RYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDE----HVQREIMNHRSLKHP 365 RYE+ +G G +G K + + A+K I + DE H++REI SL HP Sbjct: 55 RYELQETLGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDELDMVHIRREIEIMSSLNHP 114 Query: 366 NIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFF 503 +II EV + I+MEYAS GEL+ I R SE E R FF Sbjct: 115 HIISIYEVFENKDKIVIIMEYASKGELYDYISERRRLSERETRHFF 160 Score = 25.0 bits (53), Expect(2) = 1e-12 Identities = 9/17 (52%), Positives = 11/17 (64%) Frame = +2 Query: 506 QLISGVSYCHSMQVCHR 556 Q++S V YCH V HR Sbjct: 162 QIVSAVHYCHKNGVVHR 178
>DCAK2_HUMAN (Q8N568) Serine/threonine-protein kinase DCAMKL2 (EC 2.7.11.1)| (Doublecortin-like and CAM kinase-like 2) Length = 766 Score = 70.9 bits (172), Expect = 2e-12 Identities = 39/108 (36%), Positives = 63/108 (58%), Gaps = 2/108 (1%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKID-EH-VQREIMNHRSLKHP 365 +++Y++ + IG GNF V K D T + FA+K I++ EH ++ E+ R +KHP Sbjct: 391 LEKYKIGKVIGDGNFAVVKECIDRSTGKEFALKIIDKAKCCGKEHLIENEVSILRRVKHP 450 Query: 366 NIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFFHN 509 NII E + T T L +VME GG+LF I ++ +++E +G +N Sbjct: 451 NIIMLVEEMETATELFLVMELVKGGDLFDAITSSTKYTERDGSAMVYN 498
>AAPK1_CAEEL (P45894) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMP-activated kinase 1) Length = 589 Score = 60.5 bits (145), Expect(2) = 2e-12 Identities = 36/105 (34%), Positives = 50/105 (47%), Gaps = 4/105 (3%) Frame = +3 Query: 201 YEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKID----EHVQREIMNHRSLKHPN 368 + + IG G FG K ++T A+K + RG + EI N + L HP+ Sbjct: 24 FVIKETIGKGAFGAVKRGTHIQTGYDVAIKILNRGRMKGLGTVNKTRNEIDNLQKLTHPH 83 Query: 369 IIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFF 503 I R V+ TP+ + +VME SGGELF I G E R +F Sbjct: 84 ITRLFRVISTPSDIFLVMELVSGGELFSYITRKGALPIRESRRYF 128 Score = 30.4 bits (67), Expect(2) = 2e-12 Identities = 11/17 (64%), Positives = 14/17 (82%) Frame = +2 Query: 506 QLISGVSYCHSMQVCHR 556 Q+ISGVSYCH+ + HR Sbjct: 130 QIISGVSYCHNHMIVHR 146
>DAPK1_MOUSE (Q80YE7) Death-associated protein kinase 1 (EC 2.7.11.1) (DAP| kinase 1) Length = 1442 Score = 62.8 bits (151), Expect(2) = 3e-12 Identities = 33/109 (30%), Positives = 55/109 (50%), Gaps = 7/109 (6%) Frame = +3 Query: 195 DRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKID-------EHVQREIMNHRS 353 D Y+ ++GSG F V K R+ T +A KFI++ E ++RE+ + Sbjct: 11 DYYDTGEELGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRGVSREDIEREVSILKE 70 Query: 354 LKHPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 ++HPN+I EV T + +++E +GGELF + +E+E F Sbjct: 71 IRHPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEF 119 Score = 27.7 bits (60), Expect(2) = 3e-12 Identities = 10/18 (55%), Positives = 14/18 (77%) Frame = +2 Query: 500 LPQLISGVSYCHSMQVCH 553 L Q++SGV Y HS+Q+ H Sbjct: 120 LKQILSGVYYLHSLQIAH 137
>BRSK1_HUMAN (Q8TDC3) BR serine/threonine-protein kinase 1 (EC 2.7.11.1) (SAD1| kinase) (SAD1A) Length = 794 Score = 60.8 bits (146), Expect(2) = 5e-12 Identities = 34/105 (32%), Positives = 57/105 (54%), Gaps = 4/105 (3%) Frame = +3 Query: 201 YEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEHV----QREIMNHRSLKHPN 368 Y + + +G G G+ KL T + A+K + R K+ E V +REI + ++HP+ Sbjct: 50 YRLEKTLGKGQTGLVKLGVHCITGQKVAIKIVNR-EKLSESVLMKVEREIAILKLIEHPH 108 Query: 369 IIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFF 503 +++ +V +L +V+E+ SGGELF + GR + E R FF Sbjct: 109 VLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFF 153 Score = 28.9 bits (63), Expect(2) = 5e-12 Identities = 8/17 (47%), Positives = 13/17 (76%) Frame = +2 Query: 506 QLISGVSYCHSMQVCHR 556 Q++S + +CHS +CHR Sbjct: 155 QIVSALDFCHSYSICHR 171
>SNRK_HUMAN (Q9NRH2) SNF-related serine/threonine-protein kinase (EC 2.7.11.1)| (SNF1-related kinase) Length = 765 Score = 62.4 bits (150), Expect(2) = 5e-12 Identities = 34/90 (37%), Positives = 55/90 (61%), Gaps = 4/90 (4%) Frame = +3 Query: 201 YEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDE----HVQREIMNHRSLKHPN 368 Y++ + +G G+F V KL R V T E AVK I++ K+D H+ +E+ + ++HPN Sbjct: 16 YDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKT-KLDTLATGHLFQEVRCMKLVQHPN 74 Query: 369 IIRFKEVVLTPTHLAIVMEYASGGELFQRI 458 I+R EV+ T T L +++E GG++F I Sbjct: 75 IVRLYEVIDTQTKLYLILELGDGGDMFDYI 104 Score = 27.3 bits (59), Expect(2) = 5e-12 Identities = 9/22 (40%), Positives = 13/22 (59%) Frame = +2 Query: 491 KVLLPQLISGVSYCHSMQVCHR 556 K Q++ +SYCH + V HR Sbjct: 117 KKYFAQIVHAISYCHKLHVVHR 138
>SNRK_MOUSE (Q8VDU5) SNF-related serine/threonine-protein kinase (EC 2.7.11.1)| (SNF1-related kinase) Length = 748 Score = 62.4 bits (150), Expect(2) = 5e-12 Identities = 34/90 (37%), Positives = 55/90 (61%), Gaps = 4/90 (4%) Frame = +3 Query: 201 YEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDE----HVQREIMNHRSLKHPN 368 Y++ + +G G+F V KL R V T E AVK I++ K+D H+ +E+ + ++HPN Sbjct: 16 YDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKT-KLDTLATGHLFQEVRCMKLVQHPN 74 Query: 369 IIRFKEVVLTPTHLAIVMEYASGGELFQRI 458 I+R EV+ T T L +++E GG++F I Sbjct: 75 IVRLYEVIDTQTKLYLILELGDGGDMFDYI 104 Score = 27.3 bits (59), Expect(2) = 5e-12 Identities = 9/22 (40%), Positives = 13/22 (59%) Frame = +2 Query: 491 KVLLPQLISGVSYCHSMQVCHR 556 K Q++ +SYCH + V HR Sbjct: 117 KKYFAQIVHAISYCHKLHVVHR 138
>SNRK_RAT (Q63553) SNF-related serine/threonine-protein kinase (EC 2.7.11.1)| (SNF1-related kinase) Length = 746 Score = 62.4 bits (150), Expect(2) = 5e-12 Identities = 34/90 (37%), Positives = 55/90 (61%), Gaps = 4/90 (4%) Frame = +3 Query: 201 YEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDE----HVQREIMNHRSLKHPN 368 Y++ + +G G+F V KL R V T E AVK I++ K+D H+ +E+ + ++HPN Sbjct: 16 YDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKT-KLDTLATGHLFQEVRCMKLVQHPN 74 Query: 369 IIRFKEVVLTPTHLAIVMEYASGGELFQRI 458 I+R EV+ T T L +++E GG++F I Sbjct: 75 IVRLYEVIDTQTKLYLILELGDGGDMFDYI 104 Score = 27.3 bits (59), Expect(2) = 5e-12 Identities = 9/22 (40%), Positives = 13/22 (59%) Frame = +2 Query: 491 KVLLPQLISGVSYCHSMQVCHR 556 K Q++ +SYCH + V HR Sbjct: 117 KKYFAQIVHAISYCHKLHVVHR 138
>BRSK2_HUMAN (Q8IWQ3) BR serine/threonine-protein kinase 2 (EC 2.7.11.1)| (Serine/threonine-protein kinase 29) (SAD1B) Length = 736 Score = 60.5 bits (145), Expect(2) = 7e-12 Identities = 34/105 (32%), Positives = 57/105 (54%), Gaps = 4/105 (3%) Frame = +3 Query: 201 YEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEHV----QREIMNHRSLKHPN 368 Y + + +G G G+ KL T + A+K + R K+ E V +REI + ++HP+ Sbjct: 19 YRLEKTLGKGQTGLVKLGVHCVTCQKVAIKIVNR-EKLSESVLMKVEREIAILKLIEHPH 77 Query: 369 IIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFF 503 +++ +V +L +V+E+ SGGELF + GR + E R FF Sbjct: 78 VLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFF 122 Score = 28.9 bits (63), Expect(2) = 7e-12 Identities = 9/17 (52%), Positives = 13/17 (76%) Frame = +2 Query: 506 QLISGVSYCHSMQVCHR 556 Q+IS + +CHS +CHR Sbjct: 124 QIISALDFCHSHSICHR 140
>SSP1_SCHPO (P50526) Serine/threonine-protein kinase ssp1 (EC 2.7.11.1)| Length = 652 Score = 68.9 bits (167), Expect = 9e-12 Identities = 43/119 (36%), Positives = 66/119 (55%), Gaps = 13/119 (10%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFI---ERGHKI--------DEHVQREI 338 ++ YE+++++G G G KL RD TRE A+K I ER K+ E V+REI Sbjct: 132 INHYEIIKELGRGMHGKVKLGRDTVTRELLAIKIIPKTERRPKLGRANASSQKEKVRREI 191 Query: 339 MNHRSLKHPNIIRFKEVVLTP--THLAIVMEYASGGELFQRICNAGRFSEDEGRFFFHN 509 + HPN++R +EV+ P T + +V+EY SGGE+ C++ S E R +F + Sbjct: 192 AILKKCVHPNVVRLREVIDDPSSTKVYLVLEYMSGGEVPWTDCDSPVLSISEARQYFRD 250
>NEK3_HUMAN (P51956) Serine/threonine-protein kinase Nek3 (EC 2.7.11.1)| (NimA-related protein kinase 3) (HSPK 36) Length = 506 Score = 67.4 bits (163), Expect = 3e-11 Identities = 38/91 (41%), Positives = 54/91 (59%), Gaps = 2/91 (2%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIE--RGHKIDEHVQREIMNHRSLKHP 365 MD Y V+R IG G+FG A LV+ + + FA+K I + ++ ++E + +KHP Sbjct: 1 MDDYMVLRMIGEGSFGRALLVQHESSNQMFAMKEIRLPKSFSNTQNSRKEAVLLAKMKHP 60 Query: 366 NIIRFKEVVLTPTHLAIVMEYASGGELFQRI 458 NI+ FKE HL IVMEY GG+L Q+I Sbjct: 61 NIVAFKESFEAEGHLYIVMEYCDGGDLMQKI 91
>NEK3_MOUSE (Q9R0A5) Serine/threonine-protein kinase Nek3 (EC 2.7.11.1)| (NimA-related protein kinase 3) Length = 511 Score = 67.4 bits (163), Expect = 3e-11 Identities = 38/89 (42%), Positives = 51/89 (57%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEHVQREIMNHRSLKHPNI 371 MD Y V+R IG G+FG A LV + + FA+K I + ++E + +KHPNI Sbjct: 1 MDNYTVLRVIGQGSFGRALLVLQESSNQTFAMKEIRLLKSDTQTSRKEAVLLAKMKHPNI 60 Query: 372 IRFKEVVLTPTHLAIVMEYASGGELFQRI 458 + FKE +L IVMEY GG+L QRI Sbjct: 61 VAFKESFEAEGYLYIVMEYCDGGDLMQRI 89
>DAPK3_HUMAN (O43293) Death-associated protein kinase 3 (EC 2.7.11.1) (DAP| kinase 3) (DAP-like kinase) (Dlk) (ZIP-kinase) Length = 454 Score = 67.0 bits (162), Expect = 3e-11 Identities = 34/109 (31%), Positives = 56/109 (51%), Gaps = 7/109 (6%) Frame = +3 Query: 195 DRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKID-------EHVQREIMNHRS 353 D YE+ ++GSG F + + R T + +A KFI++ E ++RE+ R Sbjct: 11 DHYEMGEELGSGQFAIVRKCRQKGTGKEYAAKFIKKRRLSSSRRGVSREEIEREVNILRE 70 Query: 354 LKHPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 ++HPNII ++ T + +++E SGGELF + +EDE F Sbjct: 71 IRHPNIITLHDIFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQF 119
>NEK1_MOUSE (P51954) Serine/threonine-protein kinase Nek1 (EC 2.7.11.1)| (NimA-related protein kinase 1) Length = 1203 Score = 66.6 bits (161), Expect = 4e-11 Identities = 40/105 (38%), Positives = 60/105 (57%), Gaps = 6/105 (5%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEHVQ---REIMNHRSLKH 362 M++Y ++ IG G+FG A LV+ H+ +K I D+ Q RE+ ++KH Sbjct: 1 MEKYVRLQKIGEGSFGKAVLVKSTEDGRHYVIKEINISRMSDKERQESRREVAVLANMKH 60 Query: 363 PNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGR---FSEDE 488 PNI+++KE L IVM+Y GG+LF+RI NA + F ED+ Sbjct: 61 PNIVQYKESFEENGSLYIVMDYCEGGDLFKRI-NAQKGALFQEDQ 104
>KAPCA_PIG (P36887) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 66.6 bits (161), Expect = 4e-11 Identities = 33/107 (30%), Positives = 60/107 (56%), Gaps = 4/107 (3%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKID----EHVQREIMNHRSLK 359 +D++E ++ +G+G+FG LV+ T HFA+K +++ + EH E +++ Sbjct: 40 LDQFERIKTLGTGSFGRVMLVKHKETGNHFAMKILDKQKVVKLKQIEHTLNEKRILQAVN 99 Query: 360 HPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 P +++ + ++L +VMEY GGE+F + GRFSE RF+ Sbjct: 100 FPFLVKLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFY 146
>KAPCG_HUMAN (P22612) cAMP-dependent protein kinase, gamma-catalytic subunit (EC| 2.7.11.11) (PKA C-gamma) Length = 350 Score = 64.7 bits (156), Expect(2) = 6e-11 Identities = 34/106 (32%), Positives = 58/106 (54%), Gaps = 4/106 (3%) Frame = +3 Query: 195 DRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKID----EHVQREIMNHRSLKH 362 D++E +R +G G+FG LVR T H+A+K + + + EH+ E +++ Sbjct: 41 DQFERLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAIDF 100 Query: 363 PNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 P +++ + ++L +VMEY GGE+F R+ GRFSE F+ Sbjct: 101 PFLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQRVGRFSEPHACFY 146 Score = 21.6 bits (44), Expect(2) = 6e-11 Identities = 7/17 (41%), Positives = 11/17 (64%) Frame = +2 Query: 506 QLISGVSYCHSMQVCHR 556 Q++ V Y HS+ + HR Sbjct: 149 QVVLAVQYLHSLDLIHR 165
>KAPCA_CANFA (Q8MJ44) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 349 Score = 66.2 bits (160), Expect = 6e-11 Identities = 33/107 (30%), Positives = 60/107 (56%), Gaps = 4/107 (3%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKID----EHVQREIMNHRSLK 359 +D++E ++ +G+G+FG LV+ T HFA+K +++ + EH E +++ Sbjct: 39 LDQFERIKTLGTGSFGRVMLVKHKETGNHFAMKILDKQKVVKLKQIEHTLNEKRILQAVN 98 Query: 360 HPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 P +++ + ++L +VMEY GGE+F + GRFSE RF+ Sbjct: 99 FPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFY 145
>KAPCA_BOVIN (P00517) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 66.2 bits (160), Expect = 6e-11 Identities = 32/107 (29%), Positives = 61/107 (57%), Gaps = 4/107 (3%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKID----EHVQREIMNHRSLK 359 +D++E ++ +G+G+FG LV+ + T H+A+K +++ + EH E +++ Sbjct: 40 LDQFERIKTLGTGSFGRVMLVKHMETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVN 99 Query: 360 HPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 P +++ + ++L +VMEY GGE+F + GRFSE RF+ Sbjct: 100 FPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFY 146
>KAPCA_SHEEP (Q9MZD9) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 65.9 bits (159), Expect = 8e-11 Identities = 32/107 (29%), Positives = 60/107 (56%), Gaps = 4/107 (3%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKID----EHVQREIMNHRSLK 359 +D++E ++ +G+G+FG LV+ T H+A+K +++ + EH E +++ Sbjct: 40 LDQFERIKTLGTGSFGRVMLVKHTETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVN 99 Query: 360 HPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 P +++ + ++L +VMEY GGE+F + GRFSE RF+ Sbjct: 100 FPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFY 146
>KCC4_MOUSE (P08414) Calcium/calmodulin-dependent protein kinase type IV (EC| 2.7.11.17) (CAM kinase-GR) (CaMK IV) Length = 469 Score = 65.9 bits (159), Expect = 8e-11 Identities = 36/101 (35%), Positives = 60/101 (59%), Gaps = 1/101 (0%) Frame = +3 Query: 195 DRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEHVQR-EIMNHRSLKHPNI 371 D +EV ++G G + + T++ +A+K +++ +D+ + R EI L HPNI Sbjct: 40 DFFEVESELGRGATSIVYRCKQKGTQKPYALKVLKK--TVDKKIVRTEIGVLLRLSHPNI 97 Query: 372 IRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGR 494 I+ KE+ TPT +++V+E +GGELF RI G +SE + R Sbjct: 98 IKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAR 138
>MELK_MOUSE (Q61846) Maternal embryonic leucine zipper kinase (EC 2.7.11.1)| (Protein kinase PK38) (mPK38) Length = 643 Score = 61.2 bits (147), Expect(2) = 9e-11 Identities = 37/103 (35%), Positives = 55/103 (53%), Gaps = 2/103 (1%) Frame = +3 Query: 201 YEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDE--HVQREIMNHRSLKHPNII 374 YE+ IG+G F KL V T E A+K +++ + V+ EI +SL+H +I Sbjct: 11 YELYETIGTGGFAKVKLACHVLTGEMVAIKIMDKNALGSDLPRVKTEIDALKSLRHQHIC 70 Query: 375 RFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFF 503 + V+ T + +V+EY GGELF I + R SE+E R F Sbjct: 71 QLYHVLETKNKIFMVLEYCPGGELFDYIISQDRLSEEETRVVF 113 Score = 24.3 bits (51), Expect(2) = 9e-11 Identities = 9/22 (40%), Positives = 14/22 (63%) Frame = +2 Query: 491 KVLLPQLISGVSYCHSMQVCHR 556 +V+ Q++S V+Y HS HR Sbjct: 110 RVVFRQILSAVAYVHSQGYAHR 131
>KCC1_YEAST (P27466) Calcium/calmodulin-dependent protein kinase I (EC| 2.7.11.17) Length = 446 Score = 60.8 bits (146), Expect(2) = 1e-10 Identities = 34/102 (33%), Positives = 57/102 (55%), Gaps = 5/102 (4%) Frame = +3 Query: 198 RYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIER----GHKID-EHVQREIMNHRSLKH 362 +Y + +G+G FGV + ++ T E AVK + + G+K+ E + E+ + L H Sbjct: 36 KYVFGKTLGAGTFGVVRQAKNTETGEDVAVKILIKKALKGNKVQLEALYDELDILQRLHH 95 Query: 363 PNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDE 488 PNI+ FK+ + I+ + A GGELF RI G+F+E++ Sbjct: 96 PNIVAFKDWFESKDKFYIITQLAKGGELFDRILKKGKFTEED 137 Score = 24.3 bits (51), Expect(2) = 1e-10 Identities = 8/20 (40%), Positives = 13/20 (65%) Frame = +2 Query: 497 LLPQLISGVSYCHSMQVCHR 556 +L +++S V Y HS + HR Sbjct: 141 ILVEILSAVKYMHSQNIVHR 160
>KPSH1_BRARE (Q501V0) Serine/threonine-protein kinase H1 homolog (EC 2.7.11.1)| Length = 422 Score = 62.4 bits (150), Expect(2) = 1e-10 Identities = 36/96 (37%), Positives = 54/96 (56%), Gaps = 1/96 (1%) Frame = +3 Query: 198 RYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEHV-QREIMNHRSLKHPNII 374 +Y++ IG G+F V TR+ +A+K IE ++ V + E+ R ++H NII Sbjct: 95 KYDIKALIGRGSFSRVVRVEHRSTRQPYAIKMIETRYREGREVCESELCVLRRVRHTNII 154 Query: 375 RFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSE 482 + EV T + +VME A+GGELF RI G F+E Sbjct: 155 QLMEVFETAERVYMVMELATGGELFDRIITRGSFTE 190 Score = 22.7 bits (47), Expect(2) = 1e-10 Identities = 7/20 (35%), Positives = 13/20 (65%) Frame = +2 Query: 497 LLPQLISGVSYCHSMQVCHR 556 +L ++ GV Y H++ + HR Sbjct: 196 VLQMVLDGVKYLHTLGITHR 215
>DAPK2_MOUSE (Q8VDF3) Death-associated protein kinase 2 (EC 2.7.11.1) (DAP| kinase 2) (DAP-kinase-related protein 1) (DRP-1) Length = 370 Score = 65.1 bits (157), Expect = 1e-10 Identities = 35/109 (32%), Positives = 55/109 (50%), Gaps = 7/109 (6%) Frame = +3 Query: 195 DRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHK-------IDEHVQREIMNHRS 353 D Y++ ++GSG F + K R+ T +A KFI++ E ++RE+ R Sbjct: 21 DFYDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVCREEIEREVSILRQ 80 Query: 354 LKHPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 + HPNII +V T + +++E SGGELF + SE+E F Sbjct: 81 VLHPNIITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEATSF 129
>KAPCA_HUMAN (P17612) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 65.1 bits (157), Expect = 1e-10 Identities = 32/107 (29%), Positives = 60/107 (56%), Gaps = 4/107 (3%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKID----EHVQREIMNHRSLK 359 +D++E ++ +G+G+FG LV+ T H+A+K +++ + EH E +++ Sbjct: 40 LDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVN 99 Query: 360 HPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 P +++ + ++L +VMEY GGE+F + GRFSE RF+ Sbjct: 100 FPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFY 146
>KCC2_YEAST (P22517) Calcium/calmodulin-dependent protein kinase II (EC| 2.7.11.17) Length = 447 Score = 61.6 bits (148), Expect(2) = 2e-10 Identities = 33/95 (34%), Positives = 54/95 (56%), Gaps = 5/95 (5%) Frame = +3 Query: 213 RDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEHVQREIMNH-----RSLKHPNIIR 377 R +G+G+FGV + R + T E A+K + + +VQ +++ + L HPNI+ Sbjct: 51 RTLGAGSFGVVRQARKLSTNEDVAIKILLKKALQGNNVQLQMLYEELSILQKLSHPNIVS 110 Query: 378 FKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSE 482 FK+ + IV + A+GGELF RI + G+F+E Sbjct: 111 FKDWFESKDKFYIVTQLATGGELFDRILSRGKFTE 145 Score = 23.1 bits (48), Expect(2) = 2e-10 Identities = 8/20 (40%), Positives = 12/20 (60%) Frame = +2 Query: 497 LLPQLISGVSYCHSMQVCHR 556 ++ Q++ V Y HS V HR Sbjct: 151 IIVQILGAVEYMHSKNVVHR 170
>DAPK3_RAT (O88764) Death-associated protein kinase 3 (EC 2.7.11.1) (DAP| kinase 3) (DAP-like kinase) (Dlk) (ZIP-kinase) Length = 448 Score = 64.7 bits (156), Expect = 2e-10 Identities = 34/109 (31%), Positives = 55/109 (50%), Gaps = 7/109 (6%) Frame = +3 Query: 195 DRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKID-------EHVQREIMNHRS 353 D YE+ ++GSG F + + + T +A KFI++ E ++RE+ R Sbjct: 11 DHYEMGEELGSGQFAIVRKCQQKGTGMEYAAKFIKKRRLPSSRRGVSREEIEREVSILRE 70 Query: 354 LKHPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 ++HPNII +V T + +++E SGGELF + +EDE F Sbjct: 71 IRHPNIITLHDVFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQF 119
>DAPK3_MOUSE (O54784) Death-associated protein kinase 3 (EC 2.7.11.1) (DAP| kinase 3) (DAP-like kinase) (Dlk) (ZIP-kinase) Length = 448 Score = 64.7 bits (156), Expect = 2e-10 Identities = 34/109 (31%), Positives = 55/109 (50%), Gaps = 7/109 (6%) Frame = +3 Query: 195 DRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKID-------EHVQREIMNHRS 353 D YE+ ++GSG F + + + T +A KFI++ E ++RE+ R Sbjct: 11 DHYEMGEELGSGQFAIVRKCQQKGTGMEYAAKFIKKRRLPSSRRGVSREEIEREVSILRE 70 Query: 354 LKHPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 ++HPNII +V T + +++E SGGELF + +EDE F Sbjct: 71 IRHPNIITLHDVFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQF 119
>KCC4_HUMAN (Q16566) Calcium/calmodulin-dependent protein kinase type IV (EC| 2.7.11.17) (CAM kinase-GR) (CaMK IV) Length = 473 Score = 63.9 bits (154), Expect = 3e-10 Identities = 35/97 (36%), Positives = 58/97 (59%), Gaps = 1/97 (1%) Frame = +3 Query: 195 DRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEHVQR-EIMNHRSLKHPNI 371 D +EV ++G G + + T++ +A+K +++ +D+ + R EI L HPNI Sbjct: 44 DFFEVESELGRGATSIVYRCKQKGTQKPYALKVLKK--TVDKKIVRTEIGVLLRLSHPNI 101 Query: 372 IRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSE 482 I+ KE+ TPT +++V+E +GGELF RI G +SE Sbjct: 102 IKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSE 138
>KCC4_RAT (P13234) Calcium/calmodulin-dependent protein kinase type IV (EC| 2.7.11.17) (CAM kinase-GR) (CaMK IV) (Calspermin) Length = 474 Score = 63.9 bits (154), Expect = 3e-10 Identities = 35/97 (36%), Positives = 58/97 (59%), Gaps = 1/97 (1%) Frame = +3 Query: 195 DRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEHVQR-EIMNHRSLKHPNI 371 D +EV ++G G + + T++ +A+K +++ +D+ + R EI L HPNI Sbjct: 40 DFFEVESELGRGATSIVYRCKQKGTQKPYALKVLKK--TVDKKIVRTEIGVLLRLSHPNI 97 Query: 372 IRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSE 482 I+ KE+ TPT +++V+E +GGELF RI G +SE Sbjct: 98 IKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSE 134
>MELK_HUMAN (Q14680) Maternal embryonic leucine zipper kinase (EC 2.7.11.1)| (hMELK) (Protein kinase PK38) (hPK38) Length = 651 Score = 58.9 bits (141), Expect(2) = 3e-10 Identities = 34/103 (33%), Positives = 55/103 (53%), Gaps = 2/103 (1%) Frame = +3 Query: 201 YEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDE--HVQREIMNHRSLKHPNII 374 YE+ IG+G F KL + T E A+K +++ + ++ EI ++L+H +I Sbjct: 11 YELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTLGSDLPRIKTEIEALKNLRHQHIC 70 Query: 375 RFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFF 503 + V+ T + +V+EY GGELF I + R SE+E R F Sbjct: 71 QLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVF 113 Score = 24.6 bits (52), Expect(2) = 3e-10 Identities = 9/22 (40%), Positives = 14/22 (63%) Frame = +2 Query: 491 KVLLPQLISGVSYCHSMQVCHR 556 +V+ Q++S V+Y HS HR Sbjct: 110 RVVFRQIVSAVAYVHSQGYAHR 131
>CHK1_CHICK (Q8AYC9) Serine/threonine-protein kinase Chk1 (EC 2.7.11.1)| Length = 476 Score = 56.6 bits (135), Expect(2) = 3e-10 Identities = 33/106 (31%), Positives = 57/106 (53%), Gaps = 2/106 (1%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKID--EHVQREIMNHRSLKHP 365 ++ +++V+ +G G +G +L + RT E AVK ++ D E++++EI ++ L H Sbjct: 6 VEDWDLVQTLGEGAYGEVQLAVNRRTEEAVAVKIVDMKRAADCPENIKKEICINKMLNHE 65 Query: 366 NIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFF 503 N+++F + +EY SGGELF RI E E + FF Sbjct: 66 NVVKFYGHRREGATQYLFLEYCSGGELFDRIEPDIGMPEPEAQRFF 111 Score = 26.9 bits (58), Expect(2) = 3e-10 Identities = 11/17 (64%), Positives = 13/17 (76%) Frame = +2 Query: 506 QLISGVSYCHSMQVCHR 556 QLI+GV Y HSM + HR Sbjct: 113 QLIAGVVYLHSMGITHR 129
>KPSH1_MOUSE (Q91YA2) Serine/threonine-protein kinase H1 (EC 2.7.11.1) (PSK-H1)| Length = 423 Score = 61.2 bits (147), Expect(2) = 3e-10 Identities = 36/96 (37%), Positives = 54/96 (56%), Gaps = 1/96 (1%) Frame = +3 Query: 198 RYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEHV-QREIMNHRSLKHPNII 374 +Y++ IG G+F V TR+ +A+K IE ++ V + E+ R ++H NII Sbjct: 96 KYDIKALIGRGSFSRVVRVEHRATRQPYAIKMIETKYREGREVCESELRVLRRVRHANII 155 Query: 375 RFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSE 482 + EV T + +VME A+GGELF RI G F+E Sbjct: 156 QLVEVFETQERVYMVMELATGGELFDRIIAKGSFTE 191 Score = 22.3 bits (46), Expect(2) = 3e-10 Identities = 7/20 (35%), Positives = 13/20 (65%) Frame = +2 Query: 497 LLPQLISGVSYCHSMQVCHR 556 +L ++ GV Y H++ + HR Sbjct: 197 VLQMVLDGVRYLHALGITHR 216
>KPSH1_HUMAN (P11801) Serine/threonine-protein kinase H1 (EC 2.7.11.1) (PSK-H1)| Length = 423 Score = 61.2 bits (147), Expect(2) = 3e-10 Identities = 36/96 (37%), Positives = 54/96 (56%), Gaps = 1/96 (1%) Frame = +3 Query: 198 RYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEHV-QREIMNHRSLKHPNII 374 +Y++ IG G+F V TR+ +A+K IE ++ V + E+ R ++H NII Sbjct: 96 KYDIKALIGRGSFSRVVRVEHRATRQPYAIKMIETKYREGREVCESELRVLRRVRHANII 155 Query: 375 RFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSE 482 + EV T + +VME A+GGELF RI G F+E Sbjct: 156 QLVEVFETQERVYMVMELATGGELFDRIIAKGSFTE 191 Score = 22.3 bits (46), Expect(2) = 3e-10 Identities = 7/20 (35%), Positives = 13/20 (65%) Frame = +2 Query: 497 LLPQLISGVSYCHSMQVCHR 556 +L ++ GV Y H++ + HR Sbjct: 197 VLQMVLDGVRYLHALGITHR 216
>KCC1B_RAT (O70150) Calcium/calmodulin-dependent protein kinase type 1B (EC| 2.7.11.17) (CaM kinase IB) (CaM kinase I beta) (CaMKI-beta) (CaM-KI beta) (Pregnancy up-regulated non-ubiquitously expressed CaM kinase homolog) Length = 343 Score = 58.9 bits (141), Expect(2) = 3e-10 Identities = 33/98 (33%), Positives = 53/98 (54%), Gaps = 2/98 (2%) Frame = +3 Query: 201 YEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEH--VQREIMNHRSLKHPNII 374 YE+ +GSG F L ++ + A+K I + + V+ EI R + HPNI+ Sbjct: 15 YEIREKLGSGAFSEVMLAQERGSAHLVALKCIPKKALRGKEALVENEIAVLRRISHPNIV 74 Query: 375 RFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDE 488 ++V +P+HL + ME +GGELF RI G ++E + Sbjct: 75 ALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKD 112 Score = 24.6 bits (52), Expect(2) = 3e-10 Identities = 9/20 (45%), Positives = 14/20 (70%) Frame = +2 Query: 497 LLPQLISGVSYCHSMQVCHR 556 L+ Q++ VSY HS+ + HR Sbjct: 116 LVGQVLGAVSYLHSLGIVHR 135
>KCC1B_MOUSE (Q9QYK9) Calcium/calmodulin-dependent protein kinase type 1B (EC| 2.7.11.17) (CaM kinase IB) (CaM kinase I beta) (CaMKI-beta) (CaM-KI beta) (Pregnancy up-regulated non-ubiquitously expressed CaM kinase homolog) Length = 343 Score = 58.9 bits (141), Expect(2) = 3e-10 Identities = 33/98 (33%), Positives = 53/98 (54%), Gaps = 2/98 (2%) Frame = +3 Query: 201 YEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEH--VQREIMNHRSLKHPNII 374 YE+ +GSG F L ++ + A+K I + + V+ EI R + HPNI+ Sbjct: 15 YEIREKLGSGAFSEVMLAQERGSAHLVALKCIPKKALRGKEALVENEIAVLRRISHPNIV 74 Query: 375 RFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDE 488 ++V +P+HL + ME +GGELF RI G ++E + Sbjct: 75 ALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKD 112 Score = 24.6 bits (52), Expect(2) = 3e-10 Identities = 9/20 (45%), Positives = 14/20 (70%) Frame = +2 Query: 497 LLPQLISGVSYCHSMQVCHR 556 L+ Q++ VSY HS+ + HR Sbjct: 116 LVGQVLGAVSYLHSLGIVHR 135
>LOK_DROME (O61267) Ovarian-specific serine/threonine-protein kinase Lok (EC| 2.7.11.1) (Protein loki) (dMNK) Length = 476 Score = 63.5 bits (153), Expect = 4e-10 Identities = 34/112 (30%), Positives = 59/112 (52%), Gaps = 10/112 (8%) Frame = +3 Query: 201 YEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERG----------HKIDEHVQREIMNHR 350 Y V R +GSG +G+ +LV D RT + FA+K +++ + V E + Sbjct: 174 YYVNRKLGSGAYGLVRLVYDTRTCQQFAMKIVKKNMLSGARPSTNFSDPDRVLNEAKIMK 233 Query: 351 SLKHPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFFH 506 +L HP ++R ++V P + +V+E+ GG+L RI + SED + +F+ Sbjct: 234 NLSHPCVVRMHDIVDKPDSVYMVLEFMRGGDLLNRIISNKLLSEDISKLYFY 285
>KAPCA_CRIGR (P25321) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 63.5 bits (153), Expect = 4e-10 Identities = 31/107 (28%), Positives = 59/107 (55%), Gaps = 4/107 (3%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKID----EHVQREIMNHRSLK 359 +D ++ ++ +G+G+FG LV+ T H+A+K +++ + EH E +++ Sbjct: 40 LDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVN 99 Query: 360 HPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 P +++ + ++L +VMEY GGE+F + GRFSE RF+ Sbjct: 100 FPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFY 146
>CDS1_SCHPO (Q09170) Serine/threonine-protein kinase cds1 (EC 2.7.11.1)| (Checkpoint kinase cds1) Length = 460 Score = 63.2 bits (152), Expect = 5e-10 Identities = 35/104 (33%), Positives = 53/104 (50%), Gaps = 8/104 (7%) Frame = +3 Query: 201 YEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGH--------KIDEHVQREIMNHRSL 356 YE++R +GSG F V KL +V + + +A+K I + + E QREI +SL Sbjct: 167 YEIIRTLGSGTFAVVKLAVEVNSGKWYAIKIINKRKILLTSSEKRATEMFQREIDILKSL 226 Query: 357 KHPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDE 488 HP +++ E+ L IVMEY GG+L + G E + Sbjct: 227 HHPGVVQCHEIFENDDELFIVMEYVEGGDLMDFLIANGSIDEQD 270
>KAPCA_MOUSE (P05132) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 63.2 bits (152), Expect = 5e-10 Identities = 30/107 (28%), Positives = 61/107 (57%), Gaps = 4/107 (3%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKID----EHVQREIMNHRSLK 359 +D+++ ++ +G+G+FG LV+ + H+A+K +++ + EH E +++ Sbjct: 40 LDQFDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVN 99 Query: 360 HPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 P +++ + ++L +VMEY +GGE+F + GRFSE RF+ Sbjct: 100 FPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFY 146
>CHK1_XENLA (Q6DE87) Serine/threonine-protein kinase Chk1 (EC 2.7.11.1) (xChk1| protein) Length = 474 Score = 56.6 bits (135), Expect(2) = 6e-10 Identities = 34/106 (32%), Positives = 58/106 (54%), Gaps = 3/106 (2%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKID--EHVQREIMNHRSLKHP 365 ++ +++V+ +G G +G +L + +T E AVK ++ D E++++EI +R L H Sbjct: 6 VEDWDLVQTLGEGAYGEVQLAVNRKTEEAVAVKIVDMTRAADCPENIKKEICINRMLSHT 65 Query: 366 NIIRFKEVVLTPTHLAIVMEYASGGELFQRI-CNAGRFSEDEGRFF 500 NI+RF + +EY GGELF RI + G +D +FF Sbjct: 66 NIVRFYGHRREGNIQYLFLEYCRGGELFDRIEPDVGMPEQDAQKFF 111 Score = 26.2 bits (56), Expect(2) = 6e-10 Identities = 10/17 (58%), Positives = 13/17 (76%) Frame = +2 Query: 506 QLISGVSYCHSMQVCHR 556 QLI+GV Y HS+ + HR Sbjct: 113 QLIAGVEYLHSIGITHR 129
>KCC1D_MOUSE (Q8BW96) Calcium/calmodulin-dependent protein kinase type 1D (EC| 2.7.11.17) (CaM kinase ID) (CaM kinase I delta) (CaMKI-delta) (CaM-KI delta) (CaMKI delta) (Camk1D) (CamKI-like protein kinase) (CKLiK) (mCKLiK) Length = 385 Score = 60.8 bits (146), Expect(2) = 6e-10 Identities = 33/98 (33%), Positives = 53/98 (54%), Gaps = 2/98 (2%) Frame = +3 Query: 201 YEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERG--HKIDEHVQREIMNHRSLKHPNII 374 +E +G+G F L + T + FAVK I + + ++ EI R +KH NI+ Sbjct: 23 FEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKESSIENEIAVLRKIKHENIV 82 Query: 375 RFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDE 488 +++ +P HL +VM+ SGGELF RI G ++E + Sbjct: 83 ALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKD 120 Score = 21.9 bits (45), Expect(2) = 6e-10 Identities = 8/20 (40%), Positives = 12/20 (60%) Frame = +2 Query: 497 LLPQLISGVSYCHSMQVCHR 556 L+ Q++ V Y H M + HR Sbjct: 124 LIRQVLDAVYYLHRMGIVHR 143
>KCC1D_HUMAN (Q8IU85) Calcium/calmodulin-dependent protein kinase type 1D (EC| 2.7.11.17) (CaM kinase ID) (CaM kinase I delta) (CaMKI-delta) (CaM-KI delta) (CaMKI delta) (Camk1D) (CamKI-like protein kinase) (CKLiK) Length = 385 Score = 60.8 bits (146), Expect(2) = 6e-10 Identities = 33/98 (33%), Positives = 53/98 (54%), Gaps = 2/98 (2%) Frame = +3 Query: 201 YEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERG--HKIDEHVQREIMNHRSLKHPNII 374 +E +G+G F L + T + FAVK I + + ++ EI R +KH NI+ Sbjct: 23 FEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKESSIENEIAVLRKIKHENIV 82 Query: 375 RFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDE 488 +++ +P HL +VM+ SGGELF RI G ++E + Sbjct: 83 ALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKD 120 Score = 21.9 bits (45), Expect(2) = 6e-10 Identities = 8/20 (40%), Positives = 12/20 (60%) Frame = +2 Query: 497 LLPQLISGVSYCHSMQVCHR 556 L+ Q++ V Y H M + HR Sbjct: 124 LIRQVLDAVYYLHRMGIVHR 143
>KCC1B_HUMAN (Q6P2M8) Calcium/calmodulin-dependent protein kinase type 1B (EC| 2.7.11.17) (CaM kinase IB) (CaM kinase I beta) (CaMKI-beta) (CaM-KI beta) (Pregnancy up-regulated non-ubiquitously expressed CaM kinase) Length = 343 Score = 58.2 bits (139), Expect(2) = 6e-10 Identities = 33/98 (33%), Positives = 53/98 (54%), Gaps = 2/98 (2%) Frame = +3 Query: 201 YEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEH--VQREIMNHRSLKHPNII 374 YE+ +GSG F L ++ + A+K I + + V+ EI R + HPNI+ Sbjct: 15 YEIRERLGSGAFSEVVLAQERGSAHLVALKCIPKKALRGKEALVENEIAVLRRISHPNIV 74 Query: 375 RFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDE 488 ++V +P+HL + ME +GGELF RI G ++E + Sbjct: 75 ALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKD 112 Score = 24.6 bits (52), Expect(2) = 6e-10 Identities = 9/20 (45%), Positives = 14/20 (70%) Frame = +2 Query: 497 LLPQLISGVSYCHSMQVCHR 556 L+ Q++ VSY HS+ + HR Sbjct: 116 LVGQVLGAVSYLHSLGIVHR 135
>AKT1_BOVIN (Q01314) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (Protein kinase B) (PKB) Length = 480 Score = 62.8 bits (151), Expect = 6e-10 Identities = 36/107 (33%), Positives = 58/107 (54%), Gaps = 4/107 (3%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKI-DEHVQREIMNHRSL---K 359 M+ +E V+ +G G FG LV++ T ++A+K +++ + + V + +R L + Sbjct: 147 MNEFEYVKLLGKGTFGKVILVKEKATAAYYAMKILKKEVIVAKDEVAHTLTENRVLQNSR 206 Query: 360 HPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 HP++ K T L VMEYA+GGELF + FSED RF+ Sbjct: 207 HPSLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFY 253
>KDC2_DROME (P16912) Protein kinase DC2 (EC 2.7.11.1)| Length = 583 Score = 62.4 bits (150), Expect = 8e-10 Identities = 32/107 (29%), Positives = 58/107 (54%), Gaps = 4/107 (3%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKID----EHVQREIMNHRSLK 359 +D Y++++ +G+G FG L RD + ++ A+K + I EHV+ E R ++ Sbjct: 271 LDDYQIIKTVGTGTFGRVCLCRDRISEKYCAMKILAMTEVIRLKQIEHVKNERNILREIR 330 Query: 360 HPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 HP +I + ++L ++ +Y GGELF + NAG+F+ F+ Sbjct: 331 HPFVISLEWSTKDDSNLYMIFDYVCGGELFTYLRNAGKFTSQTSNFY 377
>DAPK1_HUMAN (P53355) Death-associated protein kinase 1 (EC 2.7.11.1) (DAP| kinase 1) Length = 1432 Score = 62.4 bits (150), Expect = 8e-10 Identities = 33/109 (30%), Positives = 55/109 (50%), Gaps = 7/109 (6%) Frame = +3 Query: 195 DRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKID-------EHVQREIMNHRS 353 D Y+ ++GSG F V K R+ T +A KFI++ E ++RE+ + Sbjct: 11 DYYDTGEELGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRGVSREDIEREVSILKE 70 Query: 354 LKHPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 ++HPN+I EV T + +++E +GGELF + +E+E F Sbjct: 71 IQHPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEF 119
>AURKB_RAT (O55099) Serine/threonine-protein kinase 12 (EC 2.7.11.1) (Aurora-| and Ipl1-like midbody-associated protein 1) (AIM-1) (Aurora-B) Length = 343 Score = 59.3 bits (142), Expect(2) = 1e-09 Identities = 30/101 (29%), Positives = 54/101 (53%), Gaps = 4/101 (3%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGH----KIDEHVQREIMNHRSLK 359 +D +E+ R +G G FG L R+ ++R A+K + + ++ ++REI LK Sbjct: 77 IDNFEIGRPLGKGKFGNVYLAREKKSRFIVALKILFKSQIEKEGVEHQLRREIEIQAHLK 136 Query: 360 HPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSE 482 HPNI++ + +++EYA GEL++ + +G F E Sbjct: 137 HPNILQLYNYFYDQQRIYLILEYAPRGELYKELQKSGTFDE 177 Score = 22.7 bits (47), Expect(2) = 1e-09 Identities = 7/20 (35%), Positives = 12/20 (60%) Frame = +2 Query: 497 LLPQLISGVSYCHSMQVCHR 556 ++ +L + YCH +V HR Sbjct: 183 IMEELSDALMYCHKKKVIHR 202
>CDC2A_ARATH (P24100) Cell division control protein 2 homolog A (EC 2.7.11.22)| (EC 2.7.11.23) Length = 294 Score = 50.8 bits (120), Expect(2) = 1e-09 Identities = 33/83 (39%), Positives = 46/83 (55%), Gaps = 4/83 (4%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEHVQ----REIMNHRSLK 359 MD+YE V IG G +GV RD T E A+K I R + DE V REI + ++ Sbjct: 1 MDQYEKVEKIGEGTYGVVYKARDKVTNETIALKKI-RLEQEDEGVPSTAIREISLLKEMQ 59 Query: 360 HPNIIRFKEVVLTPTHLAIVMEY 428 H NI++ ++VV + L +V EY Sbjct: 60 HSNIVKLQDVVHSEKRLYLVFEY 82 Score = 31.2 bits (69), Expect(2) = 1e-09 Identities = 16/37 (43%), Positives = 21/37 (56%) Frame = +2 Query: 446 FSKDLQCREIQRG*GKVLLPQLISGVSYCHSMQVCHR 556 FSKDL K L Q++ G++YCHS +V HR Sbjct: 97 FSKDLHMI-------KTYLYQILRGIAYCHSHRVLHR 126
>SRK1_SCHPO (O94547) Serine/threonine-protein kinase srk1 (EC 2.7.11.1)| (Sty1-regulated kinase 1) Length = 580 Score = 62.0 bits (149), Expect = 1e-09 Identities = 36/114 (31%), Positives = 58/114 (50%), Gaps = 13/114 (11%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHK------------IDEH-VQR 332 +++Y +++ +G G F RT E A+K ++R ++ H + + Sbjct: 121 LEQYTLLQKMGDGAFSNVYKAIHNRTGEKVAIKVVQRAQPNTDPRDPRKRQGVESHNILK 180 Query: 333 EIMNHRSLKHPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGR 494 E+ R +KHPNII+ E + TP + +V+E A GGELF +I FSED R Sbjct: 181 EVQIMRRVKHPNIIQLLEFIQTPEYYYLVLELADGGELFHQIVRLTYFSEDLSR 234
>KAPCA_RAT (P27791) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 62.0 bits (149), Expect = 1e-09 Identities = 30/107 (28%), Positives = 59/107 (55%), Gaps = 4/107 (3%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKID----EHVQREIMNHRSLK 359 +D ++ ++ +G+G+FG LV+ + H+A+K +++ + EH E +++ Sbjct: 40 LDHFDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVN 99 Query: 360 HPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 P +++ + ++L +VMEY GGE+F + GRFSE RF+ Sbjct: 100 FPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFY 146
>STK36_HUMAN (Q9NRP7) Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused| homolog) Length = 1315 Score = 58.5 bits (140), Expect(2) = 1e-09 Identities = 37/102 (36%), Positives = 56/102 (54%), Gaps = 3/102 (2%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIE---RGHKIDEHVQREIMNHRSLKH 362 M++Y V+ IG G+FG R + + A+KFI R K ++QREI R L+H Sbjct: 1 MEKYHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLRH 60 Query: 363 PNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDE 488 PNI+ + T + +V +YA GELFQ + + G+ ED+ Sbjct: 61 PNIVHMLDSFETDKEVVVVTDYAE-GELFQILEDDGKLPEDQ 101 Score = 23.1 bits (48), Expect(2) = 1e-09 Identities = 8/22 (36%), Positives = 14/22 (63%) Frame = +2 Query: 491 KVLLPQLISGVSYCHSMQVCHR 556 + + QL+S + Y HS ++ HR Sbjct: 103 QAIAAQLVSALYYLHSHRILHR 124
>GIN4_YEAST (Q12263) Serine/threonine-protein kinase GIN4 (EC 2.7.11.1)| Length = 1142 Score = 52.8 bits (125), Expect(2) = 1e-09 Identities = 35/113 (30%), Positives = 52/113 (46%), Gaps = 18/113 (15%) Frame = +3 Query: 219 IGSGNFGVAKLVRDVRTREHFAVKFIERG------------------HKIDEHVQREIMN 344 +G G+ G +L R+ T + AVK I + + ++REI+ Sbjct: 25 LGLGSTGKVQLARNGSTGQEAAVKVISKAVFNTGNVSGTSIVGSTTPDALPYGIEREIII 84 Query: 345 HRSLKHPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFF 503 + L HPN++R +V T T L +V+EYA GELF + G E E FF Sbjct: 85 MKLLNHPNVLRLYDVWETNTDLYLVLEYAEKGELFNLLVERGPLPEHEAIRFF 137 Score = 28.9 bits (63), Expect(2) = 1e-09 Identities = 10/17 (58%), Positives = 14/17 (82%) Frame = +2 Query: 506 QLISGVSYCHSMQVCHR 556 Q+I GVSYCH++ + HR Sbjct: 139 QIIIGVSYCHALGIVHR 155
>CDPK1_PLAFK (P62343) Calcium-dependent protein kinase 1 (EC 2.7.11.1) (PfCPK)| (PfCDPK1) Length = 523 Score = 57.4 bits (137), Expect(2) = 1e-09 Identities = 36/112 (32%), Positives = 53/112 (47%), Gaps = 16/112 (14%) Frame = +3 Query: 195 DRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGH----------------KIDEHV 326 + Y VR +GSG +G L R+ A+K I++ KI E + Sbjct: 53 ESYFKVRKLGSGAYGEVLLCREKHGHGEKAIKVIKKSQFDKMKYSITNKIECDDKIHEEI 112 Query: 327 QREIMNHRSLKHPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSE 482 EI +SL HPNII+ +V + +V E+ GGELF++I N +F E Sbjct: 113 YNEISLLKSLDHPNIIKLFDVFEDKKYFYLVTEFYEGGELFEQIINRHKFDE 164 Score = 24.3 bits (51), Expect(2) = 1e-09 Identities = 7/20 (35%), Positives = 13/20 (65%) Frame = +2 Query: 497 LLPQLISGVSYCHSMQVCHR 556 ++ Q++SG+ Y H + HR Sbjct: 170 IMKQILSGICYLHKHNIVHR 189
>CDPK1_PLAF7 (P62344) Calcium-dependent protein kinase 1 (EC 2.7.11.1)| Length = 523 Score = 57.4 bits (137), Expect(2) = 1e-09 Identities = 36/112 (32%), Positives = 53/112 (47%), Gaps = 16/112 (14%) Frame = +3 Query: 195 DRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGH----------------KIDEHV 326 + Y VR +GSG +G L R+ A+K I++ KI E + Sbjct: 53 ESYFKVRKLGSGAYGEVLLCREKHGHGEKAIKVIKKSQFDKMKYSITNKIECDDKIHEEI 112 Query: 327 QREIMNHRSLKHPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSE 482 EI +SL HPNII+ +V + +V E+ GGELF++I N +F E Sbjct: 113 YNEISLLKSLDHPNIIKLFDVFEDKKYFYLVTEFYEGGELFEQIINRHKFDE 164 Score = 24.3 bits (51), Expect(2) = 1e-09 Identities = 7/20 (35%), Positives = 13/20 (65%) Frame = +2 Query: 497 LLPQLISGVSYCHSMQVCHR 556 ++ Q++SG+ Y H + HR Sbjct: 170 IMKQILSGICYLHKHNIVHR 189
>KAPCG_MACMU (O62846) cAMP-dependent protein kinase, gamma-catalytic subunit (EC| 2.7.11.11) (PKA C-gamma) (Fragment) Length = 208 Score = 61.6 bits (148), Expect = 1e-09 Identities = 31/106 (29%), Positives = 59/106 (55%), Gaps = 4/106 (3%) Frame = +3 Query: 195 DRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKID----EHVQREIMNHRSLKH 362 D++E ++ +G+G++G LVR T H+A+K +++ + EH E +++ Sbjct: 40 DQFERLKTLGTGSYGRVMLVRHRETGNHYAMKILDKQKVVRLKQVEHTLNEKRILQAINF 99 Query: 363 PNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 P +++ + ++L +VMEY GGE+F + GRFSE + F+ Sbjct: 100 PFLVKLQFSFKDNSNLYLVMEYVPGGEMFSHLRRVGRFSEPQACFY 145
>KAPB2_BOVIN (P24256) cAMP-dependent protein kinase, beta-2-catalytic subunit| (EC 2.7.11.11) (PKA C-beta-2) Length = 397 Score = 61.6 bits (148), Expect = 1e-09 Identities = 31/107 (28%), Positives = 59/107 (55%), Gaps = 4/107 (3%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKID----EHVQREIMNHRSLK 359 ++ +E + +G+G+FG LV+ T +++A+K +++ + EH E +++ Sbjct: 87 LEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVN 146 Query: 360 HPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 P ++R + ++L +VMEY GGE+F + GRFSE RF+ Sbjct: 147 FPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFY 193
>KAPCB_HUMAN (P22694) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 61.6 bits (148), Expect = 1e-09 Identities = 31/107 (28%), Positives = 59/107 (55%), Gaps = 4/107 (3%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKID----EHVQREIMNHRSLK 359 ++ +E + +G+G+FG LV+ T +++A+K +++ + EH E +++ Sbjct: 40 LEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVN 99 Query: 360 HPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 P ++R + ++L +VMEY GGE+F + GRFSE RF+ Sbjct: 100 FPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFY 146
>KAPB1_BOVIN (P05131) cAMP-dependent protein kinase, beta-1-catalytic subunit| (EC 2.7.11.11) (PKA C-beta-1) Length = 350 Score = 61.6 bits (148), Expect = 1e-09 Identities = 31/107 (28%), Positives = 59/107 (55%), Gaps = 4/107 (3%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKID----EHVQREIMNHRSLK 359 ++ +E + +G+G+FG LV+ T +++A+K +++ + EH E +++ Sbjct: 40 LEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVN 99 Query: 360 HPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 P ++R + ++L +VMEY GGE+F + GRFSE RF+ Sbjct: 100 FPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFY 146
>AKT1_CAEEL (Q17941) Serine/threonine-protein kinase akt-1 (EC 2.7.11.1)| (Protein kinase B akt-1) (PKB akt-1) Length = 541 Score = 61.6 bits (148), Expect = 1e-09 Identities = 38/124 (30%), Positives = 63/124 (50%), Gaps = 4/124 (3%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKID-EHVQREIMNHRSL---K 359 M+ ++ ++ +G G FG L ++ RT++ +A+K +++ I E V + +R L K Sbjct: 190 MEDFDFLKVLGKGTFGKVILCKEKRTQKLYAIKILKKDVIIAREEVAHTLTENRVLQRCK 249 Query: 360 HPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFFHN*FLE*AIVTR 539 HP + K +L VM++A+GGELF + G FSE RF+ L + R Sbjct: 250 HPFLTELKYSFQEQHYLCFVMQFANGGELFTHVRKCGTFSEPRARFYGAEIVLALGYLHR 309 Query: 540 CKYV 551 C V Sbjct: 310 CDIV 313
>NEK1_HUMAN (Q96PY6) Serine/threonine-protein kinase Nek1 (EC 2.7.11.1)| (NimA-related protein kinase 1) (NY-REN-55 antigen) Length = 1258 Score = 61.6 bits (148), Expect = 1e-09 Identities = 38/105 (36%), Positives = 59/105 (56%), Gaps = 6/105 (5%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIE---RGHKIDEHVQREIMNHRSLKH 362 M++Y ++ IG G+FG A LV+ + +K I K E +RE+ ++KH Sbjct: 1 MEKYVRLQKIGEGSFGKAILVKSTEDGRQYVIKEINISRMSSKEREESRREVAVLANMKH 60 Query: 363 PNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGR---FSEDE 488 PNI++++E L IVM+Y GG+LF+RI NA + F ED+ Sbjct: 61 PNIVQYRESFEENGSLYIVMDYCEGGDLFKRI-NAQKGVLFQEDQ 104
>KCC2_SCHPO (O42844) Calcium/calmodulin-dependent protein kinase type II (EC| 2.7.11.17) (CAM kinase II) Length = 504 Score = 61.6 bits (148), Expect = 1e-09 Identities = 35/104 (33%), Positives = 55/104 (52%), Gaps = 3/104 (2%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFI---ERGHKIDEHVQREIMNHRSLKH 362 +++Y+++ ++G G F + +EH AVK I E K + V +E+ R +KH Sbjct: 62 LEKYQLIENLGDGAFSQVYKAYSIDRKEHVAVKVIRKYEMNKKQRQGVFKEVNIMRRVKH 121 Query: 363 PNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGR 494 N++ + V T +VME A GGELF +I N FSE+ R Sbjct: 122 KNVVNLFDFVETEDFYHLVMELAEGGELFHQIVNFTYFSENLAR 165
>CDC2A_ANTMA (Q38772) Cell division control protein 2 homolog A (EC 2.7.11.22)| (EC 2.7.11.23) Length = 294 Score = 50.4 bits (119), Expect(2) = 2e-09 Identities = 37/102 (36%), Positives = 55/102 (53%), Gaps = 4/102 (3%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEHVQ----REIMNHRSLK 359 M++YE V IG G +GV RD T E A+K I R + DE V REI + ++ Sbjct: 1 MEQYEKVEKIGEGTYGVVYKARDRVTNETIALKKI-RLEQEDEGVPSTAIREISLLKEMQ 59 Query: 360 HPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSED 485 H NI+R ++VV + L +V EY +L + + + FS+D Sbjct: 60 HGNIVRLQDVVHSEKRLYLVFEYLD-LDLKKHMDSCPEFSQD 100 Score = 30.8 bits (68), Expect(2) = 2e-09 Identities = 11/22 (50%), Positives = 17/22 (77%) Frame = +2 Query: 491 KVLLPQLISGVSYCHSMQVCHR 556 K+ L Q++ G++YCHS +V HR Sbjct: 105 KMFLYQILRGIAYCHSHRVLHR 126
>CDC22_MEDSA (Q05006) Cell division control protein 2 homolog 2 (EC 2.7.11.22)| Length = 294 Score = 50.4 bits (119), Expect(2) = 2e-09 Identities = 33/83 (39%), Positives = 46/83 (55%), Gaps = 4/83 (4%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEHVQ----REIMNHRSLK 359 M++YE V IG G +GV RD T E A+K I R + DE V REI + ++ Sbjct: 1 MEQYEKVEKIGEGTYGVVYKARDRATNETIALKKI-RLEQEDEGVPSTAIREISLLKEMQ 59 Query: 360 HPNIIRFKEVVLTPTHLAIVMEY 428 H NI+R ++VV + L +V EY Sbjct: 60 HRNIVRLQDVVHSEKRLYLVFEY 82 Score = 30.8 bits (68), Expect(2) = 2e-09 Identities = 11/22 (50%), Positives = 17/22 (77%) Frame = +2 Query: 491 KVLLPQLISGVSYCHSMQVCHR 556 K+ L Q++ G++YCHS +V HR Sbjct: 105 KMFLYQILCGIAYCHSHRVLHR 126
>KAPCB_RAT (P68182) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 61.2 bits (147), Expect = 2e-09 Identities = 31/107 (28%), Positives = 60/107 (56%), Gaps = 4/107 (3%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKID----EHVQREIMNHRSLK 359 ++ +E + +G+G+FG LV+ T +++A+K +++ + EH E ++++ Sbjct: 40 LEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVE 99 Query: 360 HPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 P ++R + ++L +VMEY GGE+F + GRFSE RF+ Sbjct: 100 FPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFY 146
>KAPCB_MOUSE (P68181) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 61.2 bits (147), Expect = 2e-09 Identities = 31/107 (28%), Positives = 60/107 (56%), Gaps = 4/107 (3%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKID----EHVQREIMNHRSLK 359 ++ +E + +G+G+FG LV+ T +++A+K +++ + EH E ++++ Sbjct: 40 LEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVE 99 Query: 360 HPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 P ++R + ++L +VMEY GGE+F + GRFSE RF+ Sbjct: 100 FPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFY 146
>KAPCB_CRIGR (P68180) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 61.2 bits (147), Expect = 2e-09 Identities = 31/107 (28%), Positives = 60/107 (56%), Gaps = 4/107 (3%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKID----EHVQREIMNHRSLK 359 ++ +E + +G+G+FG LV+ T +++A+K +++ + EH E ++++ Sbjct: 40 LEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVE 99 Query: 360 HPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 P ++R + ++L +VMEY GGE+F + GRFSE RF+ Sbjct: 100 FPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFY 146
>KAPC_DROME (P12370) cAMP-dependent protein kinase catalytic subunit (EC| 2.7.11.11) (PKA C) Length = 352 Score = 61.2 bits (147), Expect = 2e-09 Identities = 29/107 (27%), Positives = 61/107 (57%), Gaps = 4/107 (3%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKID----EHVQREIMNHRSLK 359 +D +E ++ +G+G+FG +V+ T++++A+K +++ + EH E ++++ Sbjct: 42 LDDFERIKTLGTGSFGRVMIVQHKPTKDYYAMKILDKQKVVKLKQVEHTLNEKRILQAIQ 101 Query: 360 HPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 P ++ + ++L +V+EY GGE+F + GRFSE RF+ Sbjct: 102 FPFLVSLRYHFKDNSNLYMVLEYVPGGEMFSHLRKVGRFSEPHSRFY 148
>KCC1G_HUMAN (Q96NX5) Calcium/calmodulin-dependent protein kinase type 1G (EC| 2.7.11.17) (CaM kinase IG) (CaM kinase I gamma) (CaMKI gamma) (CaMKI-gamma) (CaM-KI gamma) (CaMKIG) (CaMK-like CREB kinase III) (CLICK III) Length = 476 Score = 59.3 bits (142), Expect(2) = 2e-09 Identities = 32/91 (35%), Positives = 52/91 (57%), Gaps = 1/91 (1%) Frame = +3 Query: 219 IGSGNFGVAKLVRDVRTREHFAVKFIERGHKI-DEHVQREIMNHRSLKHPNIIRFKEVVL 395 +GSG F LV+ T + FA+K I++ D ++ EI + +KH NI+ +++ Sbjct: 29 LGSGAFSEVFLVKQRLTGKLFALKCIKKSPAFRDSSLENEIAVLKKIKHENIVTLEDIYE 88 Query: 396 TPTHLAIVMEYASGGELFQRICNAGRFSEDE 488 + TH +VM+ SGGELF RI G ++E + Sbjct: 89 STTHYYLVMQLVSGGELFDRILERGVYTEKD 119 Score = 21.6 bits (44), Expect(2) = 2e-09 Identities = 7/21 (33%), Positives = 13/21 (61%) Frame = +2 Query: 494 VLLPQLISGVSYCHSMQVCHR 556 +++ Q++S V Y H + HR Sbjct: 122 LVIQQVLSAVKYLHENGIVHR 142
>CDC2_CHERU (P93101) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) Length = 294 Score = 51.6 bits (122), Expect(2) = 2e-09 Identities = 34/83 (40%), Positives = 46/83 (55%), Gaps = 4/83 (4%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEHVQ----REIMNHRSLK 359 MD+YE V IG G +GV RD T E A+K I R + DE V REI + ++ Sbjct: 1 MDQYEKVEKIGEGTYGVVYKARDKVTNETIALKKI-RLEQEDEGVPSTAIREISLLKEMQ 59 Query: 360 HPNIIRFKEVVLTPTHLAIVMEY 428 H NI+R ++VV + L +V EY Sbjct: 60 HGNIVRLQDVVHSEKRLYLVFEY 82 Score = 29.3 bits (64), Expect(2) = 2e-09 Identities = 11/22 (50%), Positives = 16/22 (72%) Frame = +2 Query: 491 KVLLPQLISGVSYCHSMQVCHR 556 K L Q++ G++YCHS +V HR Sbjct: 105 KRFLYQILRGIAYCHSHRVLHR 126
>DAPK2_HUMAN (Q9UIK4) Death-associated protein kinase 2 (EC 2.7.11.1) (DAP| kinase 2) (DAP-kinase-related protein 1) (DRP-1) Length = 370 Score = 60.8 bits (146), Expect = 2e-09 Identities = 33/109 (30%), Positives = 54/109 (49%), Gaps = 7/109 (6%) Frame = +3 Query: 195 DRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHK-------IDEHVQREIMNHRS 353 D Y++ ++GSG F + K R+ T +A KFI++ E ++RE+ R Sbjct: 21 DFYDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVSREEIEREVSILRQ 80 Query: 354 LKHPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 + H N+I +V T + +++E SGGELF + SE+E F Sbjct: 81 VLHHNVITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEATSF 129
>AKT2A_XENLA (Q7ZX15) RAC-beta serine/threonine-protein kinase-A (EC 2.7.11.1)| (RAC-PK-beta-A) (Protein kinase Akt-2-A) (Protein kinase B, beta-A) (PKB beta-A) Length = 486 Score = 60.8 bits (146), Expect = 2e-09 Identities = 37/107 (34%), Positives = 56/107 (52%), Gaps = 4/107 (3%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKI--DE--HVQREIMNHRSLK 359 M+ ++ ++ +G G FG LVR+ T ++A+K + + I DE H E ++ K Sbjct: 154 MNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTLTESRVLQNTK 213 Query: 360 HPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 HP + K T L VMEYA+GGELF + F+ED RF+ Sbjct: 214 HPFLTALKYAFQTSDRLCFVMEYANGGELFFHLSRERVFTEDRARFY 260
>CDPK1_PLAYO (Q7RAH3) Calcium-dependent protein kinase 1 (EC 2.7.11.1)| Length = 534 Score = 56.2 bits (134), Expect(2) = 3e-09 Identities = 34/110 (30%), Positives = 52/110 (47%), Gaps = 14/110 (12%) Frame = +3 Query: 195 DRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGH--------------KIDEHVQR 332 + Y VR +GSG +G L ++ A+K I++ K E + Sbjct: 54 ESYFKVRKLGSGAYGEVLLCKEKNGHSEKAIKVIKKSQFDKGRYNDDNKNIEKFHEEIYN 113 Query: 333 EIMNHRSLKHPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSE 482 EI +SL HPNII+ +V + +V E+ GGELF++I N +F E Sbjct: 114 EISLLKSLDHPNIIKLFDVFEDKKYFYLVTEFYEGGELFEQIINRHKFDE 163 Score = 24.3 bits (51), Expect(2) = 3e-09 Identities = 7/20 (35%), Positives = 13/20 (65%) Frame = +2 Query: 497 LLPQLISGVSYCHSMQVCHR 556 ++ Q++SG+ Y H + HR Sbjct: 169 IMKQILSGICYLHKHNIVHR 188
>CDC2_VIGAC (Q41639) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) Length = 294 Score = 49.7 bits (117), Expect(2) = 3e-09 Identities = 33/83 (39%), Positives = 46/83 (55%), Gaps = 4/83 (4%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEHVQ----REIMNHRSLK 359 M++YE V IG G +GV RD T E A+K I R + DE V REI + ++ Sbjct: 1 MEQYEKVEKIGEGTYGVVYKARDRVTNETIALKKI-RLEQEDEGVPSTAIREISLLKEMQ 59 Query: 360 HPNIIRFKEVVLTPTHLAIVMEY 428 H NI+R ++VV + L +V EY Sbjct: 60 HRNIVRLQDVVHSEKRLYLVFEY 82 Score = 30.8 bits (68), Expect(2) = 3e-09 Identities = 11/22 (50%), Positives = 17/22 (77%) Frame = +2 Query: 491 KVLLPQLISGVSYCHSMQVCHR 556 K+ L Q++ G++YCHS +V HR Sbjct: 105 KMFLYQILCGIAYCHSHRVLHR 126
>KAPCB_PIG (P05383) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 60.5 bits (145), Expect = 3e-09 Identities = 31/107 (28%), Positives = 59/107 (55%), Gaps = 4/107 (3%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKID----EHVQREIMNHRSLK 359 ++ +E + +G+G+FG LV+ T +++A+K +++ + EH E +++ Sbjct: 40 LEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVN 99 Query: 360 HPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 P ++R + ++L +VMEY GGE+F + GRFSE RF+ Sbjct: 100 FPFLVRLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFY 146
>STK36_MOUSE (Q69ZM6) Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused| homolog) Length = 1268 Score = 57.0 bits (136), Expect(2) = 3e-09 Identities = 37/102 (36%), Positives = 55/102 (53%), Gaps = 3/102 (2%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIE---RGHKIDEHVQREIMNHRSLKH 362 M++Y V+ IG G+FG R + + A+KFI R K ++QREI R L H Sbjct: 1 MEKYHVLEMIGEGSFGRVYKGRKKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLWH 60 Query: 363 PNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDE 488 PNI+ + T + +V +YA GELFQ + + G+ ED+ Sbjct: 61 PNIVHMLDSFETDKEVVVVTDYAE-GELFQILEDDGKLPEDQ 101 Score = 23.1 bits (48), Expect(2) = 3e-09 Identities = 8/22 (36%), Positives = 14/22 (63%) Frame = +2 Query: 491 KVLLPQLISGVSYCHSMQVCHR 556 + + QL+S + Y HS ++ HR Sbjct: 103 QAIAAQLVSALYYLHSHRILHR 124
>KCC1G_MOUSE (Q91VB2) Calcium/calmodulin-dependent protein kinase type 1G (EC| 2.7.11.17) (CaM kinase IG) (CaM kinase I gamma) (CaMKI gamma) (CaMKI-gamma) (CaM-KI gamma) (CaMKIG) (CaMK-like CREB kinase III) (CLICK III) Length = 477 Score = 58.5 bits (140), Expect(2) = 4e-09 Identities = 32/91 (35%), Positives = 52/91 (57%), Gaps = 1/91 (1%) Frame = +3 Query: 219 IGSGNFGVAKLVRDVRTREHFAVKFIERGHKI-DEHVQREIMNHRSLKHPNIIRFKEVVL 395 +GSG F LV+ T + FA+K I++ D ++ EI + +KH NI+ +++ Sbjct: 29 LGSGAFSEVFLVKQRVTGKLFALKCIKKSPAFRDSSLENEIAVLKRIKHENIVTLEDIYE 88 Query: 396 TPTHLAIVMEYASGGELFQRICNAGRFSEDE 488 + TH +VM+ SGGELF RI G ++E + Sbjct: 89 STTHYYLVMQLVSGGELFDRILERGVYTEKD 119 Score = 21.6 bits (44), Expect(2) = 4e-09 Identities = 7/21 (33%), Positives = 13/21 (61%) Frame = +2 Query: 494 VLLPQLISGVSYCHSMQVCHR 556 +++ Q++S V Y H + HR Sbjct: 122 LVIQQVLSAVKYLHENGIVHR 142
>KCC1G_RAT (Q7TNJ7) Calcium/calmodulin-dependent protein kinase type 1G (EC| 2.7.11.17) (CaM kinase IG) (CaM kinase I gamma) (CaMKI gamma) (CaMKI-gamma) (CaM-KI gamma) (CaMKIG) (CaMK-like CREB kinase III) (CLICK III) Length = 476 Score = 58.5 bits (140), Expect(2) = 4e-09 Identities = 32/91 (35%), Positives = 52/91 (57%), Gaps = 1/91 (1%) Frame = +3 Query: 219 IGSGNFGVAKLVRDVRTREHFAVKFIERGHKI-DEHVQREIMNHRSLKHPNIIRFKEVVL 395 +GSG F LV+ T + FA+K I++ D ++ EI + +KH NI+ +++ Sbjct: 29 LGSGAFSEVFLVKQRVTGKLFALKCIKKSPAFRDSSLENEIAVLKRIKHENIVTLEDIYE 88 Query: 396 TPTHLAIVMEYASGGELFQRICNAGRFSEDE 488 + TH +VM+ SGGELF RI G ++E + Sbjct: 89 STTHYYLVMQLVSGGELFDRILERGVYTEKD 119 Score = 21.6 bits (44), Expect(2) = 4e-09 Identities = 7/21 (33%), Positives = 13/21 (61%) Frame = +2 Query: 494 VLLPQLISGVSYCHSMQVCHR 556 +++ Q++S V Y H + HR Sbjct: 122 LVIQQVLSAVKYLHENGIVHR 142
>CHK1_RAT (Q91ZN7) Serine/threonine-protein kinase Chk1 (EC 2.7.11.1)| Length = 476 Score = 57.4 bits (137), Expect(2) = 4e-09 Identities = 33/107 (30%), Positives = 58/107 (54%), Gaps = 2/107 (1%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKID--EHVQREIMNHRSLKHP 365 ++ +++V+ +G G +G +L + T E AVK ++ ID E++++EI ++ L H Sbjct: 6 VEDWDLVQTLGEGAYGEVQLAVNRITEEAVAVKIVDMKRAIDCPENIKKEICINKMLNHE 65 Query: 366 NIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFFH 506 N+++F + +EY SGGELF RI E + + FFH Sbjct: 66 NVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEQDAQRFFH 112 Score = 22.7 bits (47), Expect(2) = 4e-09 Identities = 8/17 (47%), Positives = 12/17 (70%) Frame = +2 Query: 506 QLISGVSYCHSMQVCHR 556 QL++GV Y H + + HR Sbjct: 113 QLMAGVVYLHGIGITHR 129
>STK6L_XENLA (Q91819) Serine/threonine-protein kinase Eg2-like (EC 2.7.11.1)| (p46XlEg22) Length = 408 Score = 55.5 bits (132), Expect(2) = 4e-09 Identities = 27/107 (25%), Positives = 55/107 (51%), Gaps = 4/107 (3%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHK----IDEHVQREIMNHRSLK 359 ++ +E+ R +G G FG L R+ ++ A+K + + ++ ++RE+ L+ Sbjct: 137 LEDFEIGRPLGKGKFGNVYLARERESKFILALKVLFKSQLEKAGVEHQLRREVEIQSHLR 196 Query: 360 HPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 HPNI+R + + ++++YA GGELF+ + RF + + Sbjct: 197 HPNILRLYGYFHDASRVYLILDYAPGGELFRELQKCTRFDDQRSALY 243 Score = 24.6 bits (52), Expect(2) = 4e-09 Identities = 9/19 (47%), Positives = 12/19 (63%) Frame = +2 Query: 500 LPQLISGVSYCHSMQVCHR 556 + QL + YCHS +V HR Sbjct: 244 IKQLAEALLYCHSKKVIHR 262
>STK6_XENLA (Q91820) Serine/threonine-protein kinase Eg2 (EC 2.7.11.1) (pEg2)| (p46Eg265) Length = 407 Score = 55.5 bits (132), Expect(2) = 4e-09 Identities = 27/107 (25%), Positives = 55/107 (51%), Gaps = 4/107 (3%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHK----IDEHVQREIMNHRSLK 359 ++ +E+ R +G G FG L R+ ++ A+K + + ++ ++RE+ L+ Sbjct: 137 LEDFEIGRPLGKGKFGNVYLARERESKFILALKVLFKSQLEKAGVEHQLRREVEIQSHLR 196 Query: 360 HPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 HPNI+R + + ++++YA GGELF+ + RF + + Sbjct: 197 HPNILRLYGYFHDASRVYLILDYAPGGELFRELQKCTRFDDQRSAMY 243 Score = 24.6 bits (52), Expect(2) = 4e-09 Identities = 9/19 (47%), Positives = 12/19 (63%) Frame = +2 Query: 500 LPQLISGVSYCHSMQVCHR 556 + QL + YCHS +V HR Sbjct: 244 IKQLAEALLYCHSKKVIHR 262
>AKT1_XENLA (Q98TY9) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (Protein kinase Akt-1) (Protein kinase B, alpha) (PKB alpha) (xAkt) Length = 481 Score = 60.1 bits (144), Expect = 4e-09 Identities = 35/107 (32%), Positives = 57/107 (53%), Gaps = 4/107 (3%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKI-DEHVQREIMNHRSL---K 359 M+ +E ++ +G G FG LV++ T ++A+K +++ + + V + +R L + Sbjct: 148 MNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSR 207 Query: 360 HPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 HP + K T L VMEYA+GGELF + FSED RF+ Sbjct: 208 HPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERIFSEDRARFY 254
>AKT1_RAT (P47196) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (Protein kinase B) (PKB) Length = 480 Score = 60.1 bits (144), Expect = 4e-09 Identities = 35/107 (32%), Positives = 57/107 (53%), Gaps = 4/107 (3%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKI-DEHVQREIMNHRSL---K 359 M+ +E ++ +G G FG LV++ T ++A+K +++ + + V + +R L + Sbjct: 147 MNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSR 206 Query: 360 HPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 HP + K T L VMEYA+GGELF + FSED RF+ Sbjct: 207 HPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFY 253
>AKT1_MOUSE (P31750) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (AKT1 kinase) (Protein kinase B) (PKB) (C-AKT) (Thymoma viral proto-oncogene) Length = 480 Score = 60.1 bits (144), Expect = 4e-09 Identities = 35/107 (32%), Positives = 57/107 (53%), Gaps = 4/107 (3%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKI-DEHVQREIMNHRSL---K 359 M+ +E ++ +G G FG LV++ T ++A+K +++ + + V + +R L + Sbjct: 147 MNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSR 206 Query: 360 HPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 HP + K T L VMEYA+GGELF + FSED RF+ Sbjct: 207 HPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFY 253
>AKT1_HUMAN (P31749) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (Protein kinase B) (PKB) (C-AKT) Length = 480 Score = 60.1 bits (144), Expect = 4e-09 Identities = 35/107 (32%), Positives = 57/107 (53%), Gaps = 4/107 (3%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKI-DEHVQREIMNHRSL---K 359 M+ +E ++ +G G FG LV++ T ++A+K +++ + + V + +R L + Sbjct: 147 MNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSR 206 Query: 360 HPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 HP + K T L VMEYA+GGELF + FSED RF+ Sbjct: 207 HPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFY 253
>AKT_MLVAT (P31748) AKT kinase transforming protein (EC 2.7.11.1)| Length = 501 Score = 60.1 bits (144), Expect = 4e-09 Identities = 35/107 (32%), Positives = 57/107 (53%), Gaps = 4/107 (3%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKI-DEHVQREIMNHRSL---K 359 M+ +E ++ +G G FG LV++ T ++A+K +++ + + V + +R L + Sbjct: 168 MNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSR 227 Query: 360 HPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 HP + K T L VMEYA+GGELF + FSED RF+ Sbjct: 228 HPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFY 274
>KCC4_YEAST (P25389) Probable serine/threonine-protein kinase KCC4 (EC| 2.7.11.1) Length = 1037 Score = 51.2 bits (121), Expect(2) = 5e-09 Identities = 32/102 (31%), Positives = 52/102 (50%), Gaps = 12/102 (11%) Frame = +3 Query: 219 IGSGNFGVAKLVRDVRTREHFAVKFIERG-------HKIDE-----HVQREIMNHRSLKH 362 +G G+ G +L + RT AVK I + H D+ +++REI+ + L H Sbjct: 27 LGFGSTGKVQLAQHERTGHRTAVKVISKSIFNNNGNHSNDDSVLPYNIEREIVIMKLLSH 86 Query: 363 PNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDE 488 PN++ +V T +L +++EYA GELF + + G E E Sbjct: 87 PNVLSLYDVWETNNNLYLILEYAEKGELFNLLVDHGPLPERE 128 Score = 28.5 bits (62), Expect(2) = 5e-09 Identities = 9/17 (52%), Positives = 14/17 (82%) Frame = +2 Query: 506 QLISGVSYCHSMQVCHR 556 Q+I G+SYCH++ + HR Sbjct: 135 QIIIGISYCHALGIVHR 151
>KPSH1_PINFU (Q4KTY1) Serine/threonine-protein kinase H1 homolog (EC 2.7.11.1)| Length = 415 Score = 57.8 bits (138), Expect(2) = 5e-09 Identities = 36/95 (37%), Positives = 52/95 (54%) Frame = +3 Query: 198 RYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEHVQREIMNHRSLKHPNIIR 377 +Y++ IG GNF V T++ +A+K I+R E + E+ R +KH II+ Sbjct: 79 KYDIKALIGRGNFSKVVRVEHRVTKQPYAIKMIDRVQG-KEVFESEVAVLRRVKHSYIIQ 137 Query: 378 FKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSE 482 EV T + +VME A+GGELF RI G F+E Sbjct: 138 LIEVFETKDKVYMVMELATGGELFDRIIAKGSFTE 172 Score = 21.9 bits (45), Expect(2) = 5e-09 Identities = 7/20 (35%), Positives = 12/20 (60%) Frame = +2 Query: 497 LLPQLISGVSYCHSMQVCHR 556 +L ++ GV Y H + + HR Sbjct: 178 VLNMVLDGVKYLHGLGITHR 197
>AURKB_MOUSE (O70126) Serine/threonine-protein kinase 12 (EC 2.7.11.1)| (Aurora-related kinase 2) (Serine/threonine-protein kinase 5) (STK-1) (Aurora-B) Length = 345 Score = 56.2 bits (134), Expect(2) = 5e-09 Identities = 29/101 (28%), Positives = 53/101 (52%), Gaps = 4/101 (3%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGH----KIDEHVQREIMNHRSLK 359 +D +E+ R +G G FG L R+ ++R A+K + + ++ ++REI LK Sbjct: 79 IDNFEIGRPLGKGKFGNVYLAREKKSRFIVALKILFKSQIEKEGVEHQLRREIEIQAHLK 138 Query: 360 HPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSE 482 HPNI++ + +++EYA GEL++ + + F E Sbjct: 139 HPNILQLYNYFYDQQRIYLILEYAPRGELYKELQKSRTFDE 179 Score = 23.5 bits (49), Expect(2) = 5e-09 Identities = 7/20 (35%), Positives = 13/20 (65%) Frame = +2 Query: 497 LLPQLISGVSYCHSMQVCHR 556 ++ +L ++YCH +V HR Sbjct: 185 IMEELSDALTYCHKKKVIHR 204
>CDC2_VIGUN (P52389) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) Length = 294 Score = 48.9 bits (115), Expect(2) = 5e-09 Identities = 33/83 (39%), Positives = 46/83 (55%), Gaps = 4/83 (4%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEHVQ----REIMNHRSLK 359 M++YE V IG G +GV RD T E A+K I R + DE V REI + ++ Sbjct: 1 MEQYEKVEKIGEGTYGVVYKARDRVTDETIALKKI-RLEQEDEGVPSTAIREISLLKEMQ 59 Query: 360 HPNIIRFKEVVLTPTHLAIVMEY 428 H NI+R ++VV + L +V EY Sbjct: 60 HRNIVRLQDVVHSEKRLYLVFEY 82 Score = 30.8 bits (68), Expect(2) = 5e-09 Identities = 11/22 (50%), Positives = 17/22 (77%) Frame = +2 Query: 491 KVLLPQLISGVSYCHSMQVCHR 556 K+ L Q++ G++YCHS +V HR Sbjct: 105 KMFLYQILCGIAYCHSHRVLHR 126
>STK36_PONPY (Q5RAJ5) Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused| homolog) Length = 1315 Score = 56.2 bits (134), Expect(2) = 6e-09 Identities = 36/102 (35%), Positives = 55/102 (53%), Gaps = 3/102 (2%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIE---RGHKIDEHVQREIMNHRSLKH 362 M++Y V+ IG G+FG R + + A+KFI R K ++QREI R L+H Sbjct: 1 MEKYHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLRH 60 Query: 363 PNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDE 488 PNI+ + T + +V +YA GEL Q + + G+ ED+ Sbjct: 61 PNIVHMLDSFETDKEVVVVTDYAE-GELLQILEDDGKLPEDQ 101 Score = 23.1 bits (48), Expect(2) = 6e-09 Identities = 8/22 (36%), Positives = 14/22 (63%) Frame = +2 Query: 491 KVLLPQLISGVSYCHSMQVCHR 556 + + QL+S + Y HS ++ HR Sbjct: 103 QAIAAQLVSALYYLHSHRILHR 124
>CDPK3_ORYSA (P53684) Calcium-dependent protein kinase, isoform 11 (EC 2.7.11.1)| (CDPK 11) Length = 542 Score = 56.6 bits (135), Expect(2) = 6e-09 Identities = 38/102 (37%), Positives = 53/102 (51%), Gaps = 6/102 (5%) Frame = +3 Query: 195 DRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKID----EHVQREI--MNHRSL 356 + Y + R +G G FG L ++ T +A K I + I E V+REI M+H S Sbjct: 77 EHYIIGRKLGQGQFGTTYLCTEINTGCEYACKTIPKRKLITKEDVEDVRREIQIMHHLS- 135 Query: 357 KHPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSE 482 H N++ K+V + IVME +GGELF RI G +SE Sbjct: 136 GHKNVVAIKDVYEDGQAVHIVMELCAGGELFDRIQEKGHYSE 177 Score = 22.7 bits (47), Expect(2) = 6e-09 Identities = 9/20 (45%), Positives = 14/20 (70%) Frame = +2 Query: 497 LLPQLISGVSYCHSMQVCHR 556 L+ ++S V+ CHS+ V HR Sbjct: 183 LIRIIVSIVAMCHSLGVMHR 202
>CHK1_MOUSE (O35280) Serine/threonine-protein kinase Chk1 (EC 2.7.11.1)| Length = 476 Score = 56.6 bits (135), Expect(2) = 6e-09 Identities = 33/107 (30%), Positives = 58/107 (54%), Gaps = 2/107 (1%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKID--EHVQREIMNHRSLKHP 365 ++ +++V+ +G G +G +L + T E AVK ++ ID E++++EI ++ L H Sbjct: 6 VEDWDLVQTLGEGAYGEVQLAVNRITEEAVAVKIVDMKRAIDCPENIKKEICINKMLSHE 65 Query: 366 NIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFFH 506 N+++F + +EY SGGELF RI E + + FFH Sbjct: 66 NVVKFYGHRREGHIQYLFLEYCSGGELFDRIEPDIGMPEQDAQRFFH 112 Score = 22.7 bits (47), Expect(2) = 6e-09 Identities = 8/17 (47%), Positives = 12/17 (70%) Frame = +2 Query: 506 QLISGVSYCHSMQVCHR 556 QL++GV Y H + + HR Sbjct: 113 QLMAGVVYLHGIGITHR 129
>CHK1_HUMAN (O14757) Serine/threonine-protein kinase Chk1 (EC 2.7.11.1)| Length = 476 Score = 56.6 bits (135), Expect(2) = 6e-09 Identities = 32/107 (29%), Positives = 58/107 (54%), Gaps = 2/107 (1%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKID--EHVQREIMNHRSLKHP 365 ++ +++V+ +G G +G +L + T E AVK ++ +D E++++EI ++ L H Sbjct: 6 VEDWDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCPENIKKEICINKMLNHE 65 Query: 366 NIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFFH 506 N+++F + +EY SGGELF RI E + + FFH Sbjct: 66 NVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFH 112 Score = 22.7 bits (47), Expect(2) = 6e-09 Identities = 8/17 (47%), Positives = 12/17 (70%) Frame = +2 Query: 506 QLISGVSYCHSMQVCHR 556 QL++GV Y H + + HR Sbjct: 113 QLMAGVVYLHGIGITHR 129
>KCC1A_HUMAN (Q14012) Calcium/calmodulin-dependent protein kinase type 1 (EC| 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha) Length = 370 Score = 58.2 bits (139), Expect(2) = 6e-09 Identities = 36/106 (33%), Positives = 55/106 (51%), Gaps = 3/106 (2%) Frame = +3 Query: 195 DRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFI--ERGHKIDEHVQREIMNHRSLKHPN 368 D Y+ +G+G F L D RT++ A+K I E + ++ EI +KHPN Sbjct: 18 DIYDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKEALEGKEGSMENEIAVLHKIKHPN 77 Query: 369 IIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSE-DEGRFFF 503 I+ ++ + HL ++M+ SGGELF RI G ++E D R F Sbjct: 78 IVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIF 123 Score = 21.2 bits (43), Expect(2) = 6e-09 Identities = 7/20 (35%), Positives = 12/20 (60%) Frame = +2 Query: 497 LLPQLISGVSYCHSMQVCHR 556 L+ Q++ V Y H + + HR Sbjct: 121 LIFQVLDAVKYLHDLGIVHR 140
>AKT2B_XENLA (Q6IP76) RAC-beta serine/threonine-protein kinase-B (EC 2.7.11.1)| (RAC-PK-beta-B) (Protein kinase Akt-2-B) (Protein kinase B, beta-B) (PKB beta-B) Length = 485 Score = 59.3 bits (142), Expect = 7e-09 Identities = 37/107 (34%), Positives = 56/107 (52%), Gaps = 4/107 (3%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKI--DE--HVQREIMNHRSLK 359 M+ ++ ++ +G G FG LVR+ T ++A+K + + I DE H E ++ K Sbjct: 153 MNDFDYLKLLGKGTFGKVILVREKATGLYYAMKILRKEVIIAKDEVAHTLTESRVLQNTK 212 Query: 360 HPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 HP + K T L VMEYA+GGELF + F+ED RF+ Sbjct: 213 HPFLTGLKYAFQTSDRLCFVMEYANGGELFFHLSRERVFTEDRARFY 259
>AKT2_MOUSE (Q60823) RAC-beta serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta) Length = 481 Score = 59.3 bits (142), Expect = 7e-09 Identities = 36/107 (33%), Positives = 56/107 (52%), Gaps = 4/107 (3%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKI--DE--HVQREIMNHRSLK 359 M+ ++ ++ +G G FG LVR+ T ++A+K + + I DE H E ++ + Sbjct: 149 MNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQNTR 208 Query: 360 HPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 HP + K T L VMEYA+GGELF + F+ED RF+ Sbjct: 209 HPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEDRARFY 255
>SCH9_YEAST (P11792) Serine/threonine-protein kinase SCH9 (EC 2.7.11.1)| Length = 823 Score = 59.3 bits (142), Expect = 7e-09 Identities = 37/109 (33%), Positives = 55/109 (50%), Gaps = 9/109 (8%) Frame = +3 Query: 201 YEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIER---------GHKIDEHVQREIMNHRS 353 +EV+R +G G FG V+ T+ +A+K + + H I E + ++ S Sbjct: 411 FEVLRLLGKGTFGQVYQVKKKDTQRIYAMKVLSKKVIVKKNEIAHTIGE--RNILVTTAS 468 Query: 354 LKHPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 P I+ K TPT L +V +Y SGGELF + GRFSED +F+ Sbjct: 469 KSSPFIVGLKFSFQTPTDLYLVTDYMSGGELFWHLQKEGRFSEDRAKFY 517
>RKIN1_SECCE (Q02723) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 502 Score = 59.3 bits (142), Expect = 7e-09 Identities = 37/111 (33%), Positives = 54/111 (48%), Gaps = 7/111 (6%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGH----KIDEHVQREIMNHR--- 350 + Y + + +G G F + TR A+K + R +++E +REI R Sbjct: 11 LKNYYLGKILGVGTFAKVIIAEHKHTRHKVAIKVLNRRQMRAPEMEEKAKREIKILRLFI 70 Query: 351 SLKHPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFF 503 L HP+IIR EV++TP + +VMEY G+L I R EDE R F Sbjct: 71 DLIHPHIIRVYEVIVTPKDIFVVMEYCQNGDLLDYILEKRRLQEDEARRTF 121 Score = 29.3 bits (64), Expect = 7.8 Identities = 13/33 (39%), Positives = 18/33 (54%) Frame = +2 Query: 458 LQCREIQRG*GKVLLPQLISGVSYCHSMQVCHR 556 L+ R +Q + Q+IS V YCH +V HR Sbjct: 107 LEKRRLQEDEARRTFQQIISAVEYCHRNKVVHR 139
>CDPK4_PLAF7 (Q8IBS5) Calcium-dependent protein kinase 4 (EC 2.7.11.1)| Length = 527 Score = 53.5 bits (127), Expect(2) = 8e-09 Identities = 33/100 (33%), Positives = 53/100 (53%), Gaps = 4/100 (4%) Frame = +3 Query: 195 DRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGH---KID-EHVQREIMNHRSLKH 362 ++Y+ ++ +G G+FG L RD T +A+K I + H K D E + RE+ + L H Sbjct: 67 EQYKGIKILGKGSFGEVILSRDKHTGHEYAIKVISKKHVKRKTDKESLLREVELLKMLDH 126 Query: 363 PNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSE 482 NI++ E + +V + +GGELF I + RF E Sbjct: 127 INIMKLYEFFEDNNYYYLVSDVYTGGELFDEIISRKRFYE 166 Score = 25.4 bits (54), Expect(2) = 8e-09 Identities = 8/20 (40%), Positives = 14/20 (70%) Frame = +2 Query: 497 LLPQLISGVSYCHSMQVCHR 556 ++ Q++SG++Y H V HR Sbjct: 172 IIKQILSGITYMHKNNVVHR 191
>KCC1A_RAT (Q63450) Calcium/calmodulin-dependent protein kinase type 1 (EC| 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha) Length = 374 Score = 57.8 bits (138), Expect(2) = 8e-09 Identities = 35/106 (33%), Positives = 55/106 (51%), Gaps = 3/106 (2%) Frame = +3 Query: 195 DRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERG--HKIDEHVQREIMNHRSLKHPN 368 D Y+ +G+G F L D RT++ A+K I + + ++ EI +KHPN Sbjct: 18 DIYDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKKALEGKEGSMENEIAVLHKIKHPN 77 Query: 369 IIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSE-DEGRFFF 503 I+ ++ + HL ++M+ SGGELF RI G ++E D R F Sbjct: 78 IVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIF 123 Score = 21.2 bits (43), Expect(2) = 8e-09 Identities = 7/20 (35%), Positives = 12/20 (60%) Frame = +2 Query: 497 LLPQLISGVSYCHSMQVCHR 556 L+ Q++ V Y H + + HR Sbjct: 121 LIFQVLDAVKYLHDLGIVHR 140
>KCC1A_MOUSE (Q91YS8) Calcium/calmodulin-dependent protein kinase type 1 (EC| 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha) Length = 374 Score = 57.8 bits (138), Expect(2) = 8e-09 Identities = 35/106 (33%), Positives = 55/106 (51%), Gaps = 3/106 (2%) Frame = +3 Query: 195 DRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERG--HKIDEHVQREIMNHRSLKHPN 368 D Y+ +G+G F L D RT++ A+K I + + ++ EI +KHPN Sbjct: 18 DIYDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKKALEGKEGSMENEIAVLHKIKHPN 77 Query: 369 IIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSE-DEGRFFF 503 I+ ++ + HL ++M+ SGGELF RI G ++E D R F Sbjct: 78 IVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIF 123 Score = 21.2 bits (43), Expect(2) = 8e-09 Identities = 7/20 (35%), Positives = 12/20 (60%) Frame = +2 Query: 497 LLPQLISGVSYCHSMQVCHR 556 L+ Q++ V Y H + + HR Sbjct: 121 LIFQVLDAVKYLHDLGIVHR 140
>STK33_HUMAN (Q9BYT3) Serine/threonine-protein kinase 33 (EC 2.7.11.1)| Length = 514 Score = 57.8 bits (138), Expect(2) = 1e-08 Identities = 33/106 (31%), Positives = 56/106 (52%), Gaps = 3/106 (2%) Frame = +3 Query: 201 YEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIER---GHKIDEHVQREIMNHRSLKHPNI 371 Y R +G G+FG+ D T +A+K + + G + ++RE+ +S+KH +I Sbjct: 116 YTFGRILGKGSFGIVIEATDKETETKWAIKKVNKEKAGSSAVKLLEREVNILKSVKHEHI 175 Query: 372 IRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFFHN 509 I ++V TP + +VME GEL + + G FSE+E R+ + Sbjct: 176 IHLEQVFETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQS 221 Score = 20.8 bits (42), Expect(2) = 1e-08 Identities = 6/20 (30%), Positives = 12/20 (60%) Frame = +2 Query: 497 LLPQLISGVSYCHSMQVCHR 556 ++ L S ++Y H+ + HR Sbjct: 218 IIQSLASAIAYLHNNDIVHR 237
>KPSH2_HUMAN (Q96QS6) Serine/threonine-protein kinase H2 (EC 2.7.11.1) (PSK-H2)| Length = 385 Score = 54.7 bits (130), Expect(2) = 1e-08 Identities = 33/96 (34%), Positives = 52/96 (54%), Gaps = 1/96 (1%) Frame = +3 Query: 198 RYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIE-RGHKIDEHVQREIMNHRSLKHPNII 374 RY++ IG+G+F V T++ FA+K +E R + E E+ R + H I+ Sbjct: 62 RYDIKALIGTGSFSRVVRVEQKTTKKPFAIKVMETREREGREACVSELSVLRRVSHRYIV 121 Query: 375 RFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSE 482 + E+ T + +VME A+GGELF R+ G F+E Sbjct: 122 QLMEIFETEDQVYMVMELATGGELFDRLIAQGSFTE 157 Score = 23.9 bits (50), Expect(2) = 1e-08 Identities = 7/20 (35%), Positives = 13/20 (65%) Frame = +2 Query: 497 LLPQLISGVSYCHSMQVCHR 556 +L + G+ Y H++Q+ HR Sbjct: 163 ILQMVADGIRYLHALQITHR 182
>KS6A5_PONPY (Q5R4K3) Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1)| Length = 802 Score = 58.5 bits (140), Expect = 1e-08 Identities = 32/96 (33%), Positives = 54/96 (56%), Gaps = 1/96 (1%) Frame = +3 Query: 213 RDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEHVQREIMNHRSLK-HPNIIRFKEV 389 + +G G+F + + ++ + FAVK I + +++ + Q+EI + + HPNI++ EV Sbjct: 430 KPLGEGSFSICRKCVHKKSNQAFAVKIISK--RMEANTQKEITALKLCEGHPNIVKLHEV 487 Query: 390 VLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRF 497 H +VME +GGELF+RI FSE E + Sbjct: 488 FHDQLHTFLVMELLNGGELFERIKKKKHFSETEASY 523 Score = 48.9 bits (115), Expect = 1e-05 Identities = 29/113 (25%), Positives = 62/113 (54%), Gaps = 10/113 (8%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVR---TREHFAVKFIERGH-----KIDEHV--QREIM 341 ++ +E+++ +G+G +G LVR + T + +A+K +++ K EH +R+++ Sbjct: 46 IENFELLKVLGTGAYGKVFLVRKISGHDTGKLYAMKVLKKATIVQKAKTTEHTRTERQVL 105 Query: 342 NHRSLKHPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 H + + P ++ T T L ++++Y +GGELF + RF+E E + + Sbjct: 106 EH-TRQSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIY 157
>KS6A5_HUMAN (O75582) Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1) (Nuclear| mitogen-and stress-activated protein kinase 1) (90 kDa ribosomal protein S6 kinase 5) (RSK-like protein kinase) (RSKL) Length = 802 Score = 58.5 bits (140), Expect = 1e-08 Identities = 32/96 (33%), Positives = 54/96 (56%), Gaps = 1/96 (1%) Frame = +3 Query: 213 RDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEHVQREIMNHRSLK-HPNIIRFKEV 389 + +G G+F + + ++ + FAVK I + +++ + Q+EI + + HPNI++ EV Sbjct: 430 KPLGEGSFSICRKCVHKKSNQAFAVKIISK--RMEANTQKEITALKLCEGHPNIVKLHEV 487 Query: 390 VLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRF 497 H +VME +GGELF+RI FSE E + Sbjct: 488 FHDQLHTFLVMELLNGGELFERIKKKKHFSETEASY 523 Score = 47.8 bits (112), Expect = 2e-05 Identities = 29/113 (25%), Positives = 61/113 (53%), Gaps = 10/113 (8%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVR---TREHFAVKFIERGH-----KIDEHV--QREIM 341 ++ +E+++ +G+G +G LVR + T + +A+K +++ K EH +R+++ Sbjct: 46 IENFELLKVLGTGAYGKVFLVRKISGHDTGKLYAMKVLKKATIVQKAKTTEHTRTERQVL 105 Query: 342 NHRSLKHPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 H + P ++ T T L ++++Y +GGELF + RF+E E + + Sbjct: 106 EHIR-QSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIY 157
>AKT1_DROME (Q8INB9) RAC serine/threonine-protein kinase (EC 2.7.11.1)| (DRAC-PK) (Akt) (Dakt1) (Protein kinase B) (PKB) Length = 611 Score = 58.5 bits (140), Expect = 1e-08 Identities = 33/107 (30%), Positives = 55/107 (51%), Gaps = 4/107 (3%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDE----HVQREIMNHRSLK 359 ++ +E ++ +G G FG L R+ T + +A+K +++ I + H E +S Sbjct: 263 LENFEFLKVLGKGTFGKVILCREKATAKLYAIKILKKEVIIQKDEVAHTLTESRVLKSTN 322 Query: 360 HPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 HP +I K T L VM+Y +GGELF + + F+ED RF+ Sbjct: 323 HPFLISLKYSFQTNDRLCFVMQYVNGGELFWHLSHERIFTEDRTRFY 369
>KS6A4_MOUSE (Q9Z2B9) Ribosomal protein S6 kinase alpha-4 (EC 2.7.11.1) (Nuclear| mitogen-and stress-activated protein kinase 2) (90 kDa ribosomal protein S6 kinase 4) (RSK-like protein kinase) (RLSK) Length = 773 Score = 58.5 bits (140), Expect = 1e-08 Identities = 32/91 (35%), Positives = 51/91 (56%), Gaps = 1/91 (1%) Frame = +3 Query: 219 IGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEHVQREIMNHRSLK-HPNIIRFKEVVL 395 +G G+F V + R ++ + FAVK + R +++E+ QRE+ R + HPN++ EV+ Sbjct: 417 LGQGSFSVCRRCRQRQSGQEFAVKILSR--RLEENTQREVAALRLCQSHPNVVNLHEVLH 474 Query: 396 TPTHLAIVMEYASGGELFQRICNAGRFSEDE 488 H +V+E GGEL + I FSE E Sbjct: 475 DQLHTYLVLELLRGGELLEHIRKKRLFSESE 505 Score = 35.8 bits (81), Expect = 0.084 Identities = 27/114 (23%), Positives = 53/114 (46%), Gaps = 11/114 (9%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREH-----FAVKFIERGH-----KIDEHVQREIM 341 ++ + +++ +G+G +G LVR +T H +A+K + + K EH + E Sbjct: 30 VENFALLKVLGTGAYGKVFLVR--KTGGHDAGKLYAMKVLRKAALVQRAKTQEHTRTERS 87 Query: 342 NHRSLKH-PNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 ++ P ++ T L ++++Y SGGE+F + F E E R + Sbjct: 88 VLELVRQAPFLVTLHYAFQTDAKLHLILDYVSGGEMFTHLYQRQYFKEAEVRVY 141
>AKT2_RAT (P47197) RAC-beta serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta) Length = 481 Score = 58.2 bits (139), Expect = 2e-08 Identities = 35/107 (32%), Positives = 56/107 (52%), Gaps = 4/107 (3%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKI--DE--HVQREIMNHRSLK 359 M+ ++ ++ +G G FG LVR+ T ++A+K + + I DE H E ++ + Sbjct: 149 MNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQNTR 208 Query: 360 HPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 HP + K T L VMEYA+GG+LF + F+ED RF+ Sbjct: 209 HPFLTALKYAFQTHDRLCFVMEYANGGDLFFHLSRERVFTEDRARFY 255
>KKK1_YEAST (P34244) Probable serine/threonine-protein kinase YKL101W (EC| 2.7.11.1) Length = 1518 Score = 43.5 bits (101), Expect(2) = 2e-08 Identities = 20/60 (33%), Positives = 34/60 (56%) Frame = +3 Query: 324 VQREIMNHRSLKHPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFF 503 ++REI+ + + H N++ EV + L +V+EY GGELF + + G+ E E +F Sbjct: 161 IEREIVIMKLISHTNVMALFEVWENKSELYLVLEYVDGGELFDYLVSKGKLPEREAIHYF 220 Score = 34.3 bits (77), Expect(2) = 2e-08 Identities = 11/17 (64%), Positives = 14/17 (82%) Frame = +2 Query: 506 QLISGVSYCHSMQVCHR 556 Q++ GVSYCHS +CHR Sbjct: 222 QIVEGVSYCHSFNICHR 238
>CDR2_SCHPO (P87050) Mitosis inducer protein kinase cdr2 (EC 2.7.11.1)| Length = 775 Score = 47.8 bits (112), Expect(2) = 2e-08 Identities = 28/100 (28%), Positives = 51/100 (51%), Gaps = 4/100 (4%) Frame = +3 Query: 201 YEVVRDIGSGNFGVAKLVRDVRTREHFAVKFI----ERGHKIDEHVQREIMNHRSLKHPN 368 +E+ +GSG ++L + T + VK I E ++ E++ R ++HPN Sbjct: 10 WELGLSLGSGGPNSSRLAKHRETGQLAVVKPIVGWSELTSSQQARIEGELVLLRLIEHPN 69 Query: 369 IIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDE 488 +++ +V+ L +V+EY GGELF + G F+E + Sbjct: 70 VLQLIDVISAQEQLFVVVEYMPGGELFDCMLRKGSFTEQD 109 Score = 30.0 bits (66), Expect(2) = 2e-08 Identities = 8/17 (47%), Positives = 13/17 (76%) Frame = +2 Query: 506 QLISGVSYCHSMQVCHR 556 Q++ G+ YCH + +CHR Sbjct: 116 QILCGLEYCHKLHICHR 132
>AKT2_HUMAN (P31751) RAC-beta serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta) Length = 481 Score = 57.8 bits (138), Expect = 2e-08 Identities = 35/107 (32%), Positives = 56/107 (52%), Gaps = 4/107 (3%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKI--DE--HVQREIMNHRSLK 359 M+ ++ ++ +G G FG LVR+ T ++A+K + + I DE H E ++ + Sbjct: 149 MNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQNTR 208 Query: 360 HPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 HP + K T L VMEYA+GGELF + F+E+ RF+ Sbjct: 209 HPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFY 255
>KS6A2_MOUSE (Q9WUT3) Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1)| (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (Protein-tyrosine kinase Mpk-9) (MAP kinase-activated protein kinase 1c) (M Length = 733 Score = 57.8 bits (138), Expect = 2e-08 Identities = 39/98 (39%), Positives = 52/98 (53%) Frame = +3 Query: 195 DRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEHVQREIMNHRSLKHPNII 374 D YE+ DIG G++ V K T +AVK I++ K D + EI+ R +HPNII Sbjct: 413 DGYEIKEDIGVGSYSVCKRCVHKATDAEYAVKIIDKS-KRDPSEEIEILL-RYGQHPNII 470 Query: 375 RFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDE 488 K+V ++ +VME GGEL RI FSE E Sbjct: 471 TLKDVYDDGKYVYLVMELMRGGELLDRILRQRCFSERE 508 Score = 46.2 bits (108), Expect = 6e-05 Identities = 25/109 (22%), Positives = 60/109 (55%), Gaps = 8/109 (7%) Frame = +3 Query: 198 RYEVVRDIGSGNFGVAKLVRDVRTREH---FAVKFIERG-----HKIDEHVQREIMNHRS 353 ++E+++ +G G++G LVR V + +A+K +++ ++ ++R+I+ Sbjct: 58 QFELLKVLGQGSYGKVFLVRKVTGSDAGQLYAMKVLKKATLKVRDRVRSKMERDIL--AE 115 Query: 354 LKHPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 + HP I++ T L +++++ GG+LF R+ F+E++ +F+ Sbjct: 116 VNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFY 164
>CDPK4_PLAYO (Q7RJG2) Calcium-dependent protein kinase 4 (EC 2.7.11.1)| Length = 527 Score = 52.4 bits (124), Expect(2) = 2e-08 Identities = 32/100 (32%), Positives = 53/100 (53%), Gaps = 4/100 (4%) Frame = +3 Query: 195 DRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGH---KIDEH-VQREIMNHRSLKH 362 ++Y+ ++ +G G+FG L +D T +A+K I + H K D+ + RE+ + L H Sbjct: 67 EQYKGIKILGKGSFGEVILSKDKHTGHEYAIKVISKKHVKRKTDKQSLLREVELLKMLDH 126 Query: 363 PNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSE 482 NI++ E + +V + SGGELF I + RF E Sbjct: 127 INIMKLYEFFEDNNYYYLVSDVYSGGELFDEIISRKRFYE 166 Score = 25.0 bits (53), Expect(2) = 2e-08 Identities = 8/20 (40%), Positives = 14/20 (70%) Frame = +2 Query: 497 LLPQLISGVSYCHSMQVCHR 556 ++ Q++SG++Y H V HR Sbjct: 172 IIKQVLSGITYMHKNNVVHR 191
>CDPK4_PLABA (P62345) Calcium-dependent protein kinase 4 (EC 2.7.11.1) (PbCDPK4)| Length = 527 Score = 52.4 bits (124), Expect(2) = 2e-08 Identities = 32/100 (32%), Positives = 53/100 (53%), Gaps = 4/100 (4%) Frame = +3 Query: 195 DRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGH---KIDEH-VQREIMNHRSLKH 362 ++Y+ ++ +G G+FG L +D T +A+K I + H K D+ + RE+ + L H Sbjct: 67 EQYKGIKILGKGSFGEVILSKDKHTGHEYAIKVISKKHVKRKTDKQSLLREVELLKMLDH 126 Query: 363 PNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSE 482 NI++ E + +V + SGGELF I + RF E Sbjct: 127 INIMKLYEFFEDNNYYYLVSDVYSGGELFDEIISRKRFYE 166 Score = 25.0 bits (53), Expect(2) = 2e-08 Identities = 8/20 (40%), Positives = 14/20 (70%) Frame = +2 Query: 497 LLPQLISGVSYCHSMQVCHR 556 ++ Q++SG++Y H V HR Sbjct: 172 IIKQVLSGITYMHKNNVVHR 191
>CDC2H_DICDI (P34117) CDC2-like serine/threonine-protein kinase CRP (EC| 2.7.11.22) (EC 2.7.11.23) Length = 292 Score = 49.7 bits (117), Expect(2) = 2e-08 Identities = 29/83 (34%), Positives = 44/83 (53%), Gaps = 4/83 (4%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEHVQ----REIMNHRSLK 359 M++Y + +G G +G+ ++ T E A+K I + DE V REI + LK Sbjct: 1 MEKYSKIEKLGEGTYGIVNKAKNRETGEIVALKRIRLDSE-DEGVPCTAIREISLLKELK 59 Query: 360 HPNIIRFKEVVLTPTHLAIVMEY 428 HPNI+R +V+ T L +V EY Sbjct: 60 HPNIVRLHDVIHTERKLTLVFEY 82 Score = 27.7 bits (60), Expect(2) = 2e-08 Identities = 12/29 (41%), Positives = 18/29 (62%) Frame = +2 Query: 470 EIQRG*GKVLLPQLISGVSYCHSMQVCHR 556 EI + K + QL+ GV++CH +V HR Sbjct: 97 EISKPTIKSFMYQLLKGVAFCHDHRVLHR 125
>KAPB_YEAST (P06245) cAMP-dependent protein kinase type 2 (EC 2.7.11.11) (PKA| 2) Length = 380 Score = 57.4 bits (137), Expect = 3e-08 Identities = 29/104 (27%), Positives = 55/104 (52%), Gaps = 4/104 (3%) Frame = +3 Query: 201 YEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKID----EHVQREIMNHRSLKHPN 368 ++++R +G+G+FG LVR V ++A+K +++ + EH E + ++HP Sbjct: 70 FQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKQQVVKMKQVEHTNDERRMLKLVEHPF 129 Query: 369 IIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 +IR ++ +VM+Y GGELF + + RF +F+ Sbjct: 130 LIRMWGTFQDARNIFMVMDYIEGGELFSLLRKSQRFPNPVAKFY 173
>AKT3_RAT (Q63484) RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-gamma) (Protein kinase Akt-3) (Protein kinase B, gamma) (PKB gamma) Length = 454 Score = 57.4 bits (137), Expect = 3e-08 Identities = 35/107 (32%), Positives = 57/107 (53%), Gaps = 4/107 (3%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKI--DE--HVQREIMNHRSLK 359 M+ ++ ++ +G G FG LVR+ + +++A+K +++ I DE H E ++ + Sbjct: 145 MNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTR 204 Query: 360 HPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 HP + K T L VMEY +GGELF + FSED RF+ Sbjct: 205 HPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFY 251
>KPK1_ARATH (P42818) Serine/threonine-protein kinase AtPK1/AtPK6 (EC 2.7.11.1)| Length = 465 Score = 57.4 bits (137), Expect = 3e-08 Identities = 32/109 (29%), Positives = 60/109 (55%), Gaps = 6/109 (5%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEH------VQREIMNHRS 353 +D +EV++ +G G FG VR T E +A+K + + H ++++ +R+I+ Sbjct: 131 IDDFEVMKVVGKGAFGKVYQVRKKETSEIYAMKVMRKDHIMEKNHAEYMKAERDILT--K 188 Query: 354 LKHPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 + HP I++ K T L +V+++ +GG LF ++ + G F ED R + Sbjct: 189 IDHPFIVQLKYSFQTKYRLYLVLDFINGGHLFFQLYHQGLFREDLARVY 237
>AKT3_MOUSE (Q9WUA6) RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-gamma) (Protein kinase Akt-3) (Protein kinase B, gamma) (PKB gamma) Length = 479 Score = 57.4 bits (137), Expect = 3e-08 Identities = 35/107 (32%), Positives = 57/107 (53%), Gaps = 4/107 (3%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKI--DE--HVQREIMNHRSLK 359 M+ ++ ++ +G G FG LVR+ + +++A+K +++ I DE H E ++ + Sbjct: 145 MNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTR 204 Query: 360 HPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 HP + K T L VMEY +GGELF + FSED RF+ Sbjct: 205 HPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFY 251
>AKT3_HUMAN (Q9Y243) RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-gamma) (Protein kinase Akt-3) (Protein kinase B, gamma) (PKB gamma) (STK-2) Length = 479 Score = 57.4 bits (137), Expect = 3e-08 Identities = 35/107 (32%), Positives = 57/107 (53%), Gaps = 4/107 (3%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKI--DE--HVQREIMNHRSLK 359 M+ ++ ++ +G G FG LVR+ + +++A+K +++ I DE H E ++ + Sbjct: 145 MNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTR 204 Query: 360 HPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 HP + K T L VMEY +GGELF + FSED RF+ Sbjct: 205 HPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFY 251
>PRKX_HUMAN (P51817) Serine/threonine-protein kinase PRKX (EC 2.7.11.1)| (Protein kinase PKX1) Length = 358 Score = 57.4 bits (137), Expect = 3e-08 Identities = 33/104 (31%), Positives = 52/104 (50%), Gaps = 4/104 (3%) Frame = +3 Query: 201 YEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKI----DEHVQREIMNHRSLKHPN 368 ++ + +G+G FG LV++ + FA+K + I ++HV E + + HP Sbjct: 49 FDTLATVGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRLKQEQHVHNEKSVLKEVSHPF 108 Query: 369 IIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 +IR L ++MEY GGELF + N GRFS G F+ Sbjct: 109 LIRLFWTWHDERFLYMLMEYVPGGELFSYLRNRGRFSSTTGLFY 152
>KS6A5_CHICK (Q5F3L1) Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1)| Length = 789 Score = 57.0 bits (136), Expect = 4e-08 Identities = 31/93 (33%), Positives = 51/93 (54%), Gaps = 1/93 (1%) Frame = +3 Query: 213 RDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEHVQREIMNHRSLK-HPNIIRFKEV 389 + +G G+F + + +T + +AVK I + +++ + QREI + + HPN+++ EV Sbjct: 420 KPLGEGSFSICRKCLHKKTSQEYAVKIISK--RMEANTQREITALKLCEGHPNVVKLHEV 477 Query: 390 VLTPTHLAIVMEYASGGELFQRICNAGRFSEDE 488 H +VME GGEL +RI FSE E Sbjct: 478 YHDQLHTFLVMELLKGGELLERIQKKQHFSETE 510 Score = 48.9 bits (115), Expect = 1e-05 Identities = 30/113 (26%), Positives = 61/113 (53%), Gaps = 10/113 (8%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREH---FAVKFIERGH-----KIDEHV--QREIM 341 ++ +E+++ +G+G +G LVR V + +A+K +++ K EH +R+++ Sbjct: 36 IENFELLKVLGTGAYGKVFLVRKVSGHDAGKLYAMKVLKKATIVQKAKTTEHTRTERQVL 95 Query: 342 NHRSLKHPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 H + P ++ T T L ++++Y +GGELF + RFSE+E + + Sbjct: 96 EHIR-QSPFLVTLHYAFQTDTKLHLILDYINGGELFTHLSQRERFSENEVQIY 147
>ARK1_SCHPO (O59790) Serine/threonine-protein kinase ark1 (EC 2.7.11.1)| (Aurora-related kinase 1) Length = 355 Score = 57.0 bits (136), Expect = 4e-08 Identities = 31/99 (31%), Positives = 55/99 (55%), Gaps = 4/99 (4%) Frame = +3 Query: 201 YEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGH----KIDEHVQREIMNHRSLKHPN 368 +E+ + +G G FG L ++ +T A+K + + KI++ V+REI +L+H N Sbjct: 89 FEIGKPLGKGKFGRVYLAKEKKTGFIVALKTLHKSELVQSKIEKQVRREIEIQSNLRHKN 148 Query: 369 IIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSED 485 I+R + +++E+A GEL+Q + A RFSE+ Sbjct: 149 ILRLYGHFHDEKRIYLILEFAGRGELYQHLRRAKRFSEE 187
>KS6A2_HUMAN (Q15349) Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1)| (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (MAP kinase-activated protein kinase 1c) (MAPKAPK1C) Length = 733 Score = 57.0 bits (136), Expect = 4e-08 Identities = 39/98 (39%), Positives = 51/98 (52%) Frame = +3 Query: 195 DRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEHVQREIMNHRSLKHPNII 374 D YE+ DIG G++ V K T +AVK I++ K D + EI+ R +HPNII Sbjct: 413 DGYEIKEDIGVGSYSVCKRCVHKATDTEYAVKIIDKS-KRDPSEEIEILL-RYGQHPNII 470 Query: 375 RFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDE 488 K+V + +VME GGEL RI FSE E Sbjct: 471 TLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSERE 508 Score = 47.4 bits (111), Expect = 3e-05 Identities = 25/109 (22%), Positives = 61/109 (55%), Gaps = 8/109 (7%) Frame = +3 Query: 198 RYEVVRDIGSGNFGVAKLVRDVRTREH---FAVKFIERG-----HKIDEHVQREIMNHRS 353 ++E+++ +G G++G LVR V+ + +A+K +++ ++ ++R+I+ Sbjct: 58 QFELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVRSKMERDIL--AE 115 Query: 354 LKHPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 + HP I++ T L +++++ GG+LF R+ F+E++ +F+ Sbjct: 116 VNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFY 164
>KCC1_SCHPO (Q9P7I2) Calcium/calmodulin-dependent protein kinase type I (EC| 2.7.11.17) (CaMK-I) Length = 335 Score = 56.6 bits (135), Expect = 5e-08 Identities = 32/99 (32%), Positives = 51/99 (51%), Gaps = 4/99 (4%) Frame = +3 Query: 198 RYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERG--HKIDEHVQREI--MNHRSLKHP 365 +Y V R +G G + + + T + +A K + + K + V+ EI + S +HP Sbjct: 30 KYRVGRVLGGGTYATVREAVHIETNKMYAAKIMNKKMMEKKQDFVKNEIAILKRVSYEHP 89 Query: 366 NIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSE 482 NI+ + T +L ++ E A+GGELF RIC G F E Sbjct: 90 NILHLVDFFETVNNLYLITELATGGELFDRICAKGSFYE 128
>KAPC_CAEEL (P21137) cAMP-dependent protein kinase catalytic subunit (EC| 2.7.11.11) (PKA C) Length = 404 Score = 56.6 bits (135), Expect = 5e-08 Identities = 28/107 (26%), Positives = 59/107 (55%), Gaps = 4/107 (3%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKID----EHVQREIMNHRSLK 359 +D ++ ++ +G+G+FG LV+ ++ ++A+K +++ + EH E +++ Sbjct: 78 LDDFDRIKTLGTGSFGRVMLVKHKQSGNYYAMKILDKQKVVKLKQVEHTLNEKRILQAID 137 Query: 360 HPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 P ++ ++L +V+E+ SGGE+F + GRFSE RF+ Sbjct: 138 FPFLVNMTFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEPHSRFY 184
>KS6A3_MOUSE (P18654) Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1)| (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (MAP kinase-activated protein kinase 1b) (MAPKAPK1B) Length = 740 Score = 56.6 bits (135), Expect = 5e-08 Identities = 39/98 (39%), Positives = 51/98 (52%) Frame = +3 Query: 195 DRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEHVQREIMNHRSLKHPNII 374 D YEV DIG G++ V K T FAVK I++ K D + EI+ R +HPNII Sbjct: 420 DGYEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKS-KRDPTEEIEILL-RYGQHPNII 477 Query: 375 RFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDE 488 K+V ++ +V E GGEL +I FSE E Sbjct: 478 TLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSERE 515 Score = 47.4 bits (111), Expect = 3e-05 Identities = 25/109 (22%), Positives = 61/109 (55%), Gaps = 8/109 (7%) Frame = +3 Query: 198 RYEVVRDIGSGNFGVAKLVRDVR---TREHFAVKFIERG-----HKIDEHVQREIMNHRS 353 ++E+++ +G G+FG LV+ + R+ +A+K +++ ++ ++R+I+ Sbjct: 67 QFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMERDILVE-- 124 Query: 354 LKHPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 + HP I++ T L +++++ GG+LF R+ F+E++ +F+ Sbjct: 125 VNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFY 173
>KS6A3_HUMAN (P51812) Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1)| (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protei Length = 740 Score = 56.6 bits (135), Expect = 5e-08 Identities = 39/98 (39%), Positives = 51/98 (52%) Frame = +3 Query: 195 DRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEHVQREIMNHRSLKHPNII 374 D YEV DIG G++ V K T FAVK I++ K D + EI+ R +HPNII Sbjct: 420 DGYEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKS-KRDPTEEIEILL-RYGQHPNII 477 Query: 375 RFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDE 488 K+V ++ +V E GGEL +I FSE E Sbjct: 478 TLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSERE 515 Score = 47.4 bits (111), Expect = 3e-05 Identities = 25/109 (22%), Positives = 61/109 (55%), Gaps = 8/109 (7%) Frame = +3 Query: 198 RYEVVRDIGSGNFGVAKLVRDVR---TREHFAVKFIERG-----HKIDEHVQREIMNHRS 353 ++E+++ +G G+FG LV+ + R+ +A+K +++ ++ ++R+I+ Sbjct: 67 QFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMERDILVE-- 124 Query: 354 LKHPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 + HP I++ T L +++++ GG+LF R+ F+E++ +F+ Sbjct: 125 VNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFY 173
>STK6_HUMAN (O14965) Serine/threonine-protein kinase 6 (EC 2.7.11.1)| (Serine/threonine kinase 15) (Aurora/IPL1-related kinase 1) (Aurora-related kinase 1) (hARK1) (Aurora-A) (Breast-tumor-amplified kinase) Length = 403 Score = 50.1 bits (118), Expect(2) = 5e-08 Identities = 25/101 (24%), Positives = 53/101 (52%), Gaps = 4/101 (3%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHK----IDEHVQREIMNHRSLK 359 ++ +E+ R +G G FG L R+ +++ A+K + + ++ ++RE+ L+ Sbjct: 130 LEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLR 189 Query: 360 HPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSE 482 HPNI+R T + +++EYA G +++ + +F E Sbjct: 190 HPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDE 230 Score = 26.2 bits (56), Expect(2) = 5e-08 Identities = 9/19 (47%), Positives = 14/19 (73%) Frame = +2 Query: 500 LPQLISGVSYCHSMQVCHR 556 + +L + +SYCHS +V HR Sbjct: 237 ITELANALSYCHSKRVIHR 255
>KS6A1_MOUSE (P18653) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1)| (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 724 Score = 56.2 bits (134), Expect = 6e-08 Identities = 39/104 (37%), Positives = 51/104 (49%) Frame = +3 Query: 195 DRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEHVQREIMNHRSLKHPNII 374 D Y V IG G++ V K T +AVK I++ K D + EI+ R +HPNII Sbjct: 405 DGYVVKETIGVGSYSVCKRCVHKATNMEYAVKVIDKS-KRDPSEEIEILL-RYGQHPNII 462 Query: 375 RFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFFH 506 K+V H+ +V E GGEL +I FSE E F H Sbjct: 463 TLKDVYDDGKHVYLVTELMRGGELLDKILRQKFFSEREASFVLH 506 Score = 47.0 bits (110), Expect = 4e-05 Identities = 25/109 (22%), Positives = 60/109 (55%), Gaps = 8/109 (7%) Frame = +3 Query: 198 RYEVVRDIGSGNFGVAKLVRDVRTREH---FAVKFIERG-----HKIDEHVQREIMNHRS 353 ++E+++ +G G+FG LVR V + +A+K +++ ++ ++R+I+ Sbjct: 61 QFELLKVLGQGSFGKVFLVRKVTRPDSGHLYAMKVLKKATLKVRDRVRTKMERDIL--AD 118 Query: 354 LKHPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 + HP +++ T L +++++ GG+LF R+ F+E++ +F+ Sbjct: 119 VNHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFY 167
>CHK1_SCHPO (P34208) Serine/threonine-protein kinase chk1 (EC 2.7.11.1)| (Checkpoint kinase 1) Length = 496 Score = 51.6 bits (122), Expect(2) = 6e-08 Identities = 34/110 (30%), Positives = 51/110 (46%), Gaps = 9/110 (8%) Frame = +3 Query: 201 YEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKID--------EHVQREIMNHRSL 356 Y + R+IG+G F +L D + +AVKF+ + H + EI H+ Sbjct: 10 YHIGREIGTGAFASVRLCYDDNAKI-YAVKFVNKKHATSCMNAGVWARRMASEIQLHKLC 68 Query: 357 K-HPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFF 503 H NII F P +V+E+A GG+LF +I ED +F+F Sbjct: 69 NGHKNIIHFYNTAENPQWRWVVLEFAQGGDLFDKIEPDVGIDEDVAQFYF 118 Score = 24.3 bits (51), Expect(2) = 6e-08 Identities = 9/17 (52%), Positives = 12/17 (70%) Frame = +2 Query: 506 QLISGVSYCHSMQVCHR 556 QL+ G+S+ HS V HR Sbjct: 120 QLMEGISFMHSKGVAHR 136
>CDC2_MAIZE (P23111) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) Length = 294 Score = 46.2 bits (108), Expect(2) = 6e-08 Identities = 31/83 (37%), Positives = 43/83 (51%), Gaps = 4/83 (4%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEHVQ----REIMNHRSLK 359 M++YE V IG G +GV D T E A+K I R + DE V REI + + Sbjct: 1 MEQYEKVEKIGEGTYGVVYKALDKATNETIALKKI-RLEQEDEGVPSTAIREISLLKEMN 59 Query: 360 HPNIIRFKEVVLTPTHLAIVMEY 428 H NI+R +VV + + +V EY Sbjct: 60 HGNIVRLHDVVHSEKRIYLVFEY 82 Score = 29.6 bits (65), Expect(2) = 6e-08 Identities = 12/22 (54%), Positives = 16/22 (72%) Frame = +2 Query: 491 KVLLPQLISGVSYCHSMQVCHR 556 K L Q++ GV+YCHS +V HR Sbjct: 105 KSYLYQILHGVAYCHSHRVLHR 126
>KPC4_DROME (P83099) Putative protein kinase C, delta type homolog (EC| 2.7.11.13) Length = 643 Score = 55.8 bits (133), Expect = 8e-08 Identities = 33/108 (30%), Positives = 56/108 (51%), Gaps = 5/108 (4%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKI-DEHVQREIMNHRSL---- 356 +D + + +G G+FG L T ++A+K +++ + D+ V ++ + L Sbjct: 312 VDDFHFLAVLGKGSFGKVLLAELRDTTYYYAIKCLKKDVVLEDDDVDSTLIERKVLALGT 371 Query: 357 KHPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 KHP + T +HL VMEY +GG+L I +GRFSE+ RF+ Sbjct: 372 KHPYLCHLFCTFQTESHLFFVMEYLNGGDLMFHIQESGRFSEERARFY 419
>SGK2_HUMAN (Q9HBY8) Serine/threonine-protein kinase Sgk2 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 2) Length = 427 Score = 55.8 bits (133), Expect = 8e-08 Identities = 31/105 (29%), Positives = 53/105 (50%), Gaps = 5/105 (4%) Frame = +3 Query: 201 YEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEHVQREIMNHRSL-----KHP 365 ++ ++ IG GN+G L + +AVK +++ + + Q IM RS+ +HP Sbjct: 95 FDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKNVRHP 154 Query: 366 NIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 ++ + TP L V++Y +GGELF + RF E RF+ Sbjct: 155 FLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFY 199
>KS6A4_HUMAN (O75676) Ribosomal protein S6 kinase alpha-4 (EC 2.7.11.1) (Nuclear| mitogen-and stress-activated protein kinase 2) (90 kDa ribosomal protein S6 kinase 4) (Ribosomal protein kinase B) (RSKB) Length = 772 Score = 55.5 bits (132), Expect = 1e-07 Identities = 31/91 (34%), Positives = 49/91 (53%), Gaps = 1/91 (1%) Frame = +3 Query: 219 IGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEHVQREIMNHRSLK-HPNIIRFKEVVL 395 +G G+F V + R ++ + FAVK + R +++ + QRE+ R + HPN++ EV Sbjct: 417 LGQGSFSVCRRCRQRQSGQEFAVKILSR--RLEANTQREVAALRLCQSHPNVVNLHEVHH 474 Query: 396 TPTHLAIVMEYASGGELFQRICNAGRFSEDE 488 H +V+E GGEL + I FSE E Sbjct: 475 DQLHTYLVLELLRGGELLEHIRKKRHFSESE 505 Score = 37.7 bits (86), Expect = 0.022 Identities = 26/112 (23%), Positives = 52/112 (46%), Gaps = 9/112 (8%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREH---FAVKFIERGH-----KIDEHVQREIMNH 347 ++ +E+++ +G+G +G LVR + +A+K + + K EH + E Sbjct: 30 VENFELLKVLGTGAYGKVFLVRKAGGHDAGKLYAMKVLRKAALVQRAKTQEHTRTERSVL 89 Query: 348 RSLKH-PNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 ++ P ++ T L ++++Y SGGE+F + F E E R + Sbjct: 90 ELVRQAPFLVTLHYAFQTDAKLHLILDYVSGGEMFTHLYQRQYFKEAEVRVY 141
>CDPK2_MAIZE (P49101) Calcium-dependent protein kinase 2 (EC 2.7.11.1) (CDPK 2)| Length = 513 Score = 55.5 bits (132), Expect = 1e-07 Identities = 33/100 (33%), Positives = 53/100 (53%), Gaps = 6/100 (6%) Frame = +3 Query: 201 YEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKID----EHVQREI--MNHRSLKH 362 Y +++G G FGV L ++ + +A K I + + E ++REI M H S Sbjct: 65 YSFGKELGRGQFGVTYLCTEIASGRQYACKSISKRKLVSKADREDIRREIQIMQHLS-GQ 123 Query: 363 PNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSE 482 PNI+ F+ +++ +VME +GGELF RI G ++E Sbjct: 124 PNIVEFRGAYEDKSNVHVVMELCAGGELFDRIIAKGHYTE 163
>KPCL_RAT (Q64617) Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta)| (PKC-L) Length = 683 Score = 55.5 bits (132), Expect = 1e-07 Identities = 35/108 (32%), Positives = 55/108 (50%), Gaps = 5/108 (4%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKI-DEHVQREIMNHRSLK--- 359 +D +E +R +G G+FG L R T E +AVK +++ + D+ V+ + R L Sbjct: 352 IDNFEFIRVLGKGSFGKVMLARIKETGELYAVKVLKKDVILQDDDVECTMTEKRILSLAR 411 Query: 360 -HPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 HP + + TP L VME+ +GG+L I + RF E RF+ Sbjct: 412 NHPFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFY 459
>KPCL_MOUSE (P23298) Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta)| (PKC-L) Length = 683 Score = 55.5 bits (132), Expect = 1e-07 Identities = 35/108 (32%), Positives = 55/108 (50%), Gaps = 5/108 (4%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKI-DEHVQREIMNHRSLK--- 359 +D +E +R +G G+FG L R T E +AVK +++ + D+ V+ + R L Sbjct: 352 IDNFEFIRVLGKGSFGKVMLARIKETGELYAVKVLKKDVILQDDDVECTMTEKRILSLAR 411 Query: 360 -HPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 HP + + TP L VME+ +GG+L I + RF E RF+ Sbjct: 412 NHPFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFY 459
>KCC2A_RAT (P11275) Calcium/calmodulin-dependent protein kinase type II alpha| chain (EC 2.7.11.17) (CaM-kinase II alpha chain) (CaM kinase II alpha subunit) (CaMK-II alpha subunit) Length = 478 Score = 51.2 bits (121), Expect(2) = 1e-07 Identities = 28/99 (28%), Positives = 49/99 (49%), Gaps = 3/99 (3%) Frame = +3 Query: 195 DRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIER---GHKIDEHVQREIMNHRSLKHP 365 + Y++ ++G G F V + V + +A K I + + ++RE R LKHP Sbjct: 11 EEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHP 70 Query: 366 NIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSE 482 NI+R + + H ++ + +GGELF+ I +SE Sbjct: 71 NIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSE 109 Score = 23.9 bits (50), Expect(2) = 1e-07 Identities = 8/19 (42%), Positives = 12/19 (63%) Frame = +2 Query: 500 LPQLISGVSYCHSMQVCHR 556 + Q++ V +CH M V HR Sbjct: 116 IQQILEAVLHCHQMGVVHR 134
>KCC2A_PONPY (Q5RCC4) Calcium/calmodulin-dependent protein kinase type II alpha| chain (EC 2.7.11.17) (CaM-kinase II alpha chain) (CaM kinase II alpha subunit) (CaMK-II alpha subunit) Length = 478 Score = 51.2 bits (121), Expect(2) = 1e-07 Identities = 28/99 (28%), Positives = 49/99 (49%), Gaps = 3/99 (3%) Frame = +3 Query: 195 DRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIER---GHKIDEHVQREIMNHRSLKHP 365 + Y++ ++G G F V + V + +A K I + + ++RE R LKHP Sbjct: 11 EEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHP 70 Query: 366 NIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSE 482 NI+R + + H ++ + +GGELF+ I +SE Sbjct: 71 NIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSE 109 Score = 23.9 bits (50), Expect(2) = 1e-07 Identities = 8/19 (42%), Positives = 12/19 (63%) Frame = +2 Query: 500 LPQLISGVSYCHSMQVCHR 556 + Q++ V +CH M V HR Sbjct: 116 IQQILEAVLHCHQMGVVHR 134
>KCC2A_HUMAN (Q9UQM7) Calcium/calmodulin-dependent protein kinase type II alpha| chain (EC 2.7.11.17) (CaM-kinase II alpha chain) (CaM kinase II alpha subunit) (CaMK-II alpha subunit) Length = 478 Score = 51.2 bits (121), Expect(2) = 1e-07 Identities = 28/99 (28%), Positives = 49/99 (49%), Gaps = 3/99 (3%) Frame = +3 Query: 195 DRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIER---GHKIDEHVQREIMNHRSLKHP 365 + Y++ ++G G F V + V + +A K I + + ++RE R LKHP Sbjct: 11 EEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHP 70 Query: 366 NIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSE 482 NI+R + + H ++ + +GGELF+ I +SE Sbjct: 71 NIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSE 109 Score = 23.9 bits (50), Expect(2) = 1e-07 Identities = 8/19 (42%), Positives = 12/19 (63%) Frame = +2 Query: 500 LPQLISGVSYCHSMQVCHR 556 + Q++ V +CH M V HR Sbjct: 116 IQQILEAVLHCHQMGVVHR 134
>TSSK3_HUMAN (Q96PN8) Testis-specific serine/threonine-protein kinase 3 (EC| 2.7.11.1) (TSSK-3) (Testis-specific kinase 3) (TSK-3) (Serine/threonine-protein kinase 22C) Length = 268 Score = 48.5 bits (114), Expect(2) = 1e-07 Identities = 30/106 (28%), Positives = 53/106 (50%), Gaps = 5/106 (4%) Frame = +3 Query: 201 YEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEHVQR----EIMNHRSLKHPN 368 Y++ + IG G + K + + A+K I++ +E +QR E+ R+L H N Sbjct: 10 YQLGKTIGEGTYSKVKEAFSKKHQRKVAIKVIDKMGGPEEFIQRFLPRELQIVRTLDHKN 69 Query: 369 IIRFKEVVLTPT-HLAIVMEYASGGELFQRICNAGRFSEDEGRFFF 503 II+ E++ + + +VME A GG++F + N G E + F Sbjct: 70 IIQVYEMLESADGKICLVMELAEGGDVFDCVLNGGPLPESRAKALF 115 Score = 26.6 bits (57), Expect(2) = 1e-07 Identities = 9/22 (40%), Positives = 12/22 (54%) Frame = +2 Query: 491 KVLLPQLISGVSYCHSMQVCHR 556 K L Q++ + YCH V HR Sbjct: 112 KALFRQMVEAIRYCHGCGVAHR 133
>KS6A6_HUMAN (Q9UK32) Ribosomal protein S6 kinase alpha-6 (EC 2.7.11.1)| (S6K-alpha 6) (90 kDa ribosomal protein S6 kinase 6) (p90-RSK 6) (Ribosomal S6 kinase 4) (RSK-4) (pp90RSK4) Length = 745 Score = 55.1 bits (131), Expect = 1e-07 Identities = 37/96 (38%), Positives = 50/96 (52%) Frame = +3 Query: 201 YEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEHVQREIMNHRSLKHPNIIRF 380 YE+ DIG G++ V K T FAVK I++ K D + EI+ R +HPNII Sbjct: 426 YELKEDIGVGSYSVCKRCIHATTNMEFAVKIIDKS-KRDPSEEIEILM-RYGQHPNIITL 483 Query: 381 KEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDE 488 K+V ++ +V + GGEL RI FSE E Sbjct: 484 KDVFDDGRYVYLVTDLMKGGELLDRILKQKCFSERE 519 Score = 42.4 bits (98), Expect = 9e-04 Identities = 24/109 (22%), Positives = 59/109 (54%), Gaps = 8/109 (7%) Frame = +3 Query: 198 RYEVVRDIGSGNFGVAKLVRDVR---TREHFAVKFIERGH-----KIDEHVQREIMNHRS 353 ++E+++ +G G+FG LVR + +A+K +++ ++ ++R+I+ Sbjct: 72 QFELLKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLKKASLKVRDRVRTKMERDILVE-- 129 Query: 354 LKHPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 + HP I++ T L +++++ GG++F R+ F+E++ +F+ Sbjct: 130 VNHPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRLSKEVLFTEEDVKFY 178
>STK6_MOUSE (P97477) Serine/threonine-protein kinase 6 (EC 2.7.11.1)| (Aurora-family kinase 1) (Aurora/IPL1-related kinase 1) (Ipl1- and aurora-related kinase 1) (Aurora-A) (Serine/threonine-protein kinase Ayk1) Length = 395 Score = 48.5 bits (114), Expect(2) = 1e-07 Identities = 24/101 (23%), Positives = 53/101 (52%), Gaps = 4/101 (3%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGH----KIDEHVQREIMNHRSLK 359 ++ +++ R +G G FG L R+ +++ A+K + + ++ ++RE+ L+ Sbjct: 121 LEDFDIGRPLGKGKFGNVYLARERQSKFILALKVLFKTQLEKANVEHQLRREVEIQSHLR 180 Query: 360 HPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSE 482 HPNI+R T + +++EYA G +++ + +F E Sbjct: 181 HPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDE 221 Score = 26.2 bits (56), Expect(2) = 1e-07 Identities = 9/19 (47%), Positives = 14/19 (73%) Frame = +2 Query: 500 LPQLISGVSYCHSMQVCHR 556 + +L + +SYCHS +V HR Sbjct: 228 ITELANALSYCHSKRVIHR 246
>AURKB_HUMAN (Q96GD4) Serine/threonine-protein kinase 12 (EC 2.7.11.1) (Aurora-| and Ipl1-like midbody-associated protein 1) (AIM-1) (Aurora/IPL1-related kinase 2) (Aurora-related kinase 2) (STK-1) (Aurora-B) Length = 344 Score = 51.6 bits (122), Expect(2) = 1e-07 Identities = 28/101 (27%), Positives = 51/101 (50%), Gaps = 4/101 (3%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGH----KIDEHVQREIMNHRSLK 359 +D +E+ R +G G FG L R+ ++ A+K + + ++ ++REI L Sbjct: 74 IDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLH 133 Query: 360 HPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSE 482 HPNI+R + +++EYA GEL++ + + F E Sbjct: 134 HPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDE 174 Score = 23.1 bits (48), Expect(2) = 1e-07 Identities = 7/20 (35%), Positives = 12/20 (60%) Frame = +2 Query: 497 LLPQLISGVSYCHSMQVCHR 556 ++ +L + YCH +V HR Sbjct: 180 IMEELADALMYCHGKKVIHR 199
>CDK3_HUMAN (Q00526) Cell division protein kinase 3 (EC 2.7.11.22)| Length = 305 Score = 44.7 bits (104), Expect(2) = 1e-07 Identities = 28/84 (33%), Positives = 43/84 (51%), Gaps = 3/84 (3%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKID---EHVQREIMNHRSLKH 362 MD ++ V IG G +GV ++ T + A+K I +++ REI + LKH Sbjct: 1 MDMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKH 60 Query: 363 PNIIRFKEVVLTPTHLAIVMEYAS 434 PNI+R +VV L +V E+ S Sbjct: 61 PNIVRLLDVVHNERKLYLVFEFLS 84 Score = 30.0 bits (66), Expect(2) = 1e-07 Identities = 13/22 (59%), Positives = 16/22 (72%) Frame = +2 Query: 491 KVLLPQLISGVSYCHSMQVCHR 556 K L QL+ GVS+CHS +V HR Sbjct: 105 KSYLFQLLQGVSFCHSHRVIHR 126
>CDC21_ORYSA (P29618) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| Length = 294 Score = 45.1 bits (105), Expect(2) = 1e-07 Identities = 30/83 (36%), Positives = 43/83 (51%), Gaps = 4/83 (4%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEHVQ----REIMNHRSLK 359 M++YE IG G +GV RD T E A+K I R + DE V REI + + Sbjct: 1 MEQYEKEEKIGEGTYGVVYRARDKVTNETIALKKI-RLEQEDEGVPSTAIREISLLKEMH 59 Query: 360 HPNIIRFKEVVLTPTHLAIVMEY 428 H NI+R +V+ + + +V EY Sbjct: 60 HGNIVRLHDVIHSEKRIYLVFEY 82 Score = 29.6 bits (65), Expect(2) = 1e-07 Identities = 12/22 (54%), Positives = 16/22 (72%) Frame = +2 Query: 491 KVLLPQLISGVSYCHSMQVCHR 556 K L Q++ GV+YCHS +V HR Sbjct: 105 KSYLYQILRGVAYCHSHRVLHR 126
>TSSK3_MOUSE (Q9D2E1) Testis-specific serine/threonine-protein kinase 3 (EC| 2.7.11.1) (TSSK-3) (Testis-specific kinase 3) (TSK-3) (Serine/threonine-protein kinase 22C) Length = 268 Score = 48.1 bits (113), Expect(2) = 1e-07 Identities = 30/106 (28%), Positives = 53/106 (50%), Gaps = 5/106 (4%) Frame = +3 Query: 201 YEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEHVQR----EIMNHRSLKHPN 368 Y++ + IG G + K + + A+K I++ +E +QR E+ R+L H N Sbjct: 10 YQLGKTIGEGTYSKVKEAFSKKHQRKVAIKIIDKMGGPEEFIQRFLPRELQIVRTLDHKN 69 Query: 369 IIRFKEVVLTPT-HLAIVMEYASGGELFQRICNAGRFSEDEGRFFF 503 II+ E++ + + +VME A GG++F + N G E + F Sbjct: 70 IIQVYEMLESADGKIYLVMELAEGGDVFDCVLNGGPLPESRAKALF 115 Score = 26.6 bits (57), Expect(2) = 1e-07 Identities = 9/22 (40%), Positives = 12/22 (54%) Frame = +2 Query: 491 KVLLPQLISGVSYCHSMQVCHR 556 K L Q++ + YCH V HR Sbjct: 112 KALFRQMVEAIRYCHGCGVAHR 133
>YP141_YEAST (Q03002) Putative serine/threonine-protein kinase YPL141C (EC| 2.7.11.1) Length = 865 Score = 47.8 bits (112), Expect(2) = 2e-07 Identities = 25/72 (34%), Positives = 41/72 (56%), Gaps = 5/72 (6%) Frame = +3 Query: 282 AVKFIERG-----HKIDEHVQREIMNHRSLKHPNIIRFKEVVLTPTHLAIVMEYASGGEL 446 A+K I+R ++ + + REI + L HPNI++ +EV+ ++ IV+EYA GGE Sbjct: 78 AIKLIKRDSISNDYRKEVKIYREINALKHLSHPNIVKLEEVLQNSRYIGIVLEYACGGEF 137 Query: 447 FQRICNAGRFSE 482 ++ I R E Sbjct: 138 YKYIQKKRRLKE 149 Score = 26.6 bits (57), Expect(2) = 2e-07 Identities = 12/20 (60%), Positives = 13/20 (65%) Frame = +2 Query: 497 LLPQLISGVSYCHSMQVCHR 556 L QLISGV Y HS + HR Sbjct: 155 LFSQLISGVHYIHSKGLVHR 174
>CDPK2_ORYSA (P53683) Calcium-dependent protein kinase, isoform 2 (EC 2.7.11.1)| (CDPK 2) Length = 533 Score = 54.7 bits (130), Expect = 2e-07 Identities = 33/100 (33%), Positives = 55/100 (55%), Gaps = 6/100 (6%) Frame = +3 Query: 201 YEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKID----EHVQREI--MNHRSLKH 362 Y + +++G G FGV L ++ + + +A K I + + E ++REI M H S + Sbjct: 85 YSLGKELGRGQFGVTYLCTEIASGKQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQQ 144 Query: 363 PNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSE 482 NI+ F+ +++ +VME +GGELF RI G +SE Sbjct: 145 -NIVEFRGAYEDKSNVHVVMELCAGGELFDRIIAKGHYSE 183
>CDPK1_ARATH (Q06850) Calcium-dependent protein kinase, isoform AK1 (EC| 2.7.11.1) (CDPK) Length = 610 Score = 54.7 bits (130), Expect = 2e-07 Identities = 35/99 (35%), Positives = 49/99 (49%), Gaps = 5/99 (5%) Frame = +3 Query: 201 YEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKID----EHVQREI-MNHRSLKHP 365 Y + R +G G FG L + T + FA K I + + E V+REI + H HP Sbjct: 150 YSLGRKLGQGQFGTTFLCVEKTTGKEFACKSIAKRKLLTDEDVEDVRREIQIMHHLAGHP 209 Query: 366 NIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSE 482 N+I K + +VME +GGELF RI G ++E Sbjct: 210 NVISIKGAYEDVVAVHLVMECCAGGELFDRIIQRGHYTE 248
>SGK2_MOUSE (Q9QZS5) Serine/threonine-protein kinase Sgk2 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 2) Length = 367 Score = 54.7 bits (130), Expect = 2e-07 Identities = 30/105 (28%), Positives = 52/105 (49%), Gaps = 5/105 (4%) Frame = +3 Query: 201 YEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEHVQREIMNHRSL-----KHP 365 ++ ++ IG GN+G L + +AVK +++ + Q IM R++ +HP Sbjct: 35 FDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKNKEQNHIMAERNVLLKNVRHP 94 Query: 366 NIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 ++ + TP L V++Y +GGELF + RF E RF+ Sbjct: 95 FLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFY 139
>KPCL_HUMAN (P24723) Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta)| (PKC-L) Length = 682 Score = 54.7 bits (130), Expect = 2e-07 Identities = 34/108 (31%), Positives = 55/108 (50%), Gaps = 5/108 (4%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGH-KIDEHVQREIMNHRSLK--- 359 +D +E +R +G G+FG L R T + +AVK +++ +D+ V+ + R L Sbjct: 351 IDNFEFIRVLGKGSFGKVMLARVKETGDLYAVKVLKKDVILLDDDVECTMTEKRILSLAR 410 Query: 360 -HPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 HP + + TP L VME+ +GG+L I + RF E RF+ Sbjct: 411 NHPFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFY 458
>AKT2_CAEEL (Q9XTG7) Serine/threonine-protein kinase akt-2 (EC 2.7.11.1)| (Protein kinase B akt-2) (PKB akt-2) Length = 528 Score = 54.7 bits (130), Expect = 2e-07 Identities = 33/107 (30%), Positives = 53/107 (49%), Gaps = 4/107 (3%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDE-HVQREIMNHRSLK--- 359 MD ++ ++ +G G FG L R+ + + +A+K I + +D V + +R L Sbjct: 177 MDDFDFLKVLGQGTFGKVILCREKSSDKLYAIKIIRKEMVVDRSEVAHTLTENRVLYACV 236 Query: 360 HPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 HP + K H+ VME+A+GGELF + FSE RF+ Sbjct: 237 HPFLTLLKYSFQAQYHICFVMEFANGGELFTHLQRCKTFSEARTRFY 283
>KRAC_DICDI (P54644) RAC-family serine/threonine-protein kinase homolog (EC| 2.7.11.1) Length = 444 Score = 54.7 bits (130), Expect = 2e-07 Identities = 27/104 (25%), Positives = 54/104 (51%), Gaps = 4/104 (3%) Frame = +3 Query: 201 YEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEHVQREIMNHRSL----KHPN 368 +E++ +G G+FG VR T E +A+K + + H ++ + ++ R++ HP Sbjct: 120 FELLNLVGKGSFGKVIQVRKKDTGEVYAMKVLSKKHIVEHNEVEHTLSERNILQKINHPF 179 Query: 369 IIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 ++ T L +++Y +GGELF + +F+ED R++ Sbjct: 180 LVNLNYSFQTEDKLYFILDYVNGGELFYHLQKDKKFTEDRVRYY 223
>CDC21_MEDSA (P24923) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| (EC 2.7.11.23) (Fragment) Length = 291 Score = 43.5 bits (101), Expect(2) = 2e-07 Identities = 31/79 (39%), Positives = 42/79 (53%), Gaps = 4/79 (5%) Frame = +3 Query: 204 EVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEHVQ----REIMNHRSLKHPNI 371 E V IG G +GV RD T E A+K I R + DE V REI + ++H NI Sbjct: 2 ENVEKIGEGTYGVVYKARDRVTNETIALKKI-RLEQEDEGVPSTAIREISLLKEMQHRNI 60 Query: 372 IRFKEVVLTPTHLAIVMEY 428 +R ++VV + L +V EY Sbjct: 61 VRLQDVVHSDKRLYLVFEY 79 Score = 30.8 bits (68), Expect(2) = 2e-07 Identities = 11/22 (50%), Positives = 17/22 (77%) Frame = +2 Query: 491 KVLLPQLISGVSYCHSMQVCHR 556 K+ L Q++ G++YCHS +V HR Sbjct: 102 KMFLYQMLCGIAYCHSHRVLHR 123
>SGK2_RAT (Q8R4U9) Serine/threonine-protein kinase Sgk2 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 2) (Fragment) Length = 302 Score = 54.3 bits (129), Expect = 2e-07 Identities = 30/105 (28%), Positives = 52/105 (49%), Gaps = 5/105 (4%) Frame = +3 Query: 201 YEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEHVQREIMNHRSL-----KHP 365 ++ ++ IG GN+G L + +AVK +++ + Q IM R++ +HP Sbjct: 18 FDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKNKEQSHIMAERNVLLKNVRHP 77 Query: 366 NIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 ++ + TP L V++Y +GGELF + RF E RF+ Sbjct: 78 FLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQREHRFLEPRARFY 122
>STK6_RAT (P59241) Serine/threonine-protein kinase 6 (EC 2.7.11.1) (Aurora-A)| (ratAurA) Length = 397 Score = 47.8 bits (112), Expect(2) = 2e-07 Identities = 24/101 (23%), Positives = 53/101 (52%), Gaps = 4/101 (3%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHK----IDEHVQREIMNHRSLK 359 ++ +++ R +G G FG L R+ +++ A+K + + ++ ++RE+ L+ Sbjct: 123 LEDFDIGRPLGKGKFGNVYLAREKQSKFILALKVLFKVQLEKAGVEHQLRREVEIQSHLR 182 Query: 360 HPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSE 482 HPNI+R T + +++EYA G +++ + +F E Sbjct: 183 HPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDE 223 Score = 26.2 bits (56), Expect(2) = 2e-07 Identities = 9/19 (47%), Positives = 14/19 (73%) Frame = +2 Query: 500 LPQLISGVSYCHSMQVCHR 556 + +L + +SYCHS +V HR Sbjct: 230 ITELANALSYCHSKRVIHR 248
>CDK3_MOUSE (Q80YP0) Truncated cell division protein kinase 3 homolog| Length = 186 Score = 42.7 bits (99), Expect(2) = 2e-07 Identities = 28/82 (34%), Positives = 40/82 (48%), Gaps = 3/82 (3%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIE---RGHKIDEHVQREIMNHRSLKH 362 MD ++ V IG G +GV R+ T + A+K I + REI + LKH Sbjct: 1 MDVFQKVEKIGEGTYGVVYKARNKVTGQLVALKKIRLDLEAEGVPSTAVREISLLKELKH 60 Query: 363 PNIIRFKEVVLTPTHLAIVMEY 428 PNII+ +VV L +V E+ Sbjct: 61 PNIIKLLDVVHREKKLYMVFEF 82 Score = 31.2 bits (69), Expect(2) = 2e-07 Identities = 13/22 (59%), Positives = 16/22 (72%) Frame = +2 Query: 491 KVLLPQLISGVSYCHSMQVCHR 556 K L QL+ GVS+CHS +V HR Sbjct: 105 KSYLAQLLEGVSFCHSHRVIHR 126
>CRK_DAUCA (P53681) CDPK-related protein kinase (EC 2.7.11.1) (PK421)| Length = 602 Score = 50.1 bits (118), Expect(2) = 3e-07 Identities = 34/108 (31%), Positives = 58/108 (53%), Gaps = 9/108 (8%) Frame = +3 Query: 198 RYEVVRDIGSGNFGV---AKLVRDVRTREHFAVKFIERGHKID----EHVQREIMNHRSL 356 ++EV ++G G+FG AK + + AVK I + E V+RE+ R+L Sbjct: 147 KFEVGEEVGRGHFGYTCRAKFKKGEFKGQDVAVKVIPKAKMTTAIAIEDVRREVKILRAL 206 Query: 357 K-HPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICN-AGRFSEDEGR 494 H N+++F + T++ +VME GGEL RI + G+++ED+ + Sbjct: 207 TGHNNLVQFYDAFEDHTNVYVVMELCEGGELLDRILSRGGKYTEDDAK 254 Score = 23.5 bits (49), Expect(2) = 3e-07 Identities = 8/22 (36%), Positives = 15/22 (68%) Frame = +2 Query: 491 KVLLPQLISGVSYCHSMQVCHR 556 K ++ Q+++ V++CH V HR Sbjct: 254 KAVMIQILNVVAFCHLQGVVHR 275
>KS6A1_RAT (Q63531) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1)| (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 735 Score = 53.9 bits (128), Expect = 3e-07 Identities = 38/104 (36%), Positives = 51/104 (49%) Frame = +3 Query: 195 DRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEHVQREIMNHRSLKHPNII 374 D Y V IG G++ V K T +AVK I++ K D + EI+ R +HPNII Sbjct: 416 DGYIVKETIGVGSYSVCKRCVHKATNMEYAVKVIDKS-KRDPSEEIEILL-RYGQHPNII 473 Query: 375 RFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFFH 506 K+V H+ +V E GGEL +I FSE E F + Sbjct: 474 TLKDVYDDSKHVYLVTELMRGGELLDKILRQKFFSEREASFVLY 517 Score = 47.4 bits (111), Expect = 3e-05 Identities = 25/108 (23%), Positives = 60/108 (55%), Gaps = 8/108 (7%) Frame = +3 Query: 201 YEVVRDIGSGNFGVAKLVRDVRTREH---FAVKFIERG-----HKIDEHVQREIMNHRSL 356 +E+++ +G G+FG LVR V ++ +A+K +++ ++ ++R+I+ + Sbjct: 62 FELLKVLGQGSFGKVFLVRKVTRPDNGHLYAMKVLKKATLKVRDRVRTKMERDIL--ADV 119 Query: 357 KHPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 HP +++ T L +++++ GG+LF R+ F+E++ +F+ Sbjct: 120 NHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFY 167
>KS6A1_HUMAN (Q15418) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1)| (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 735 Score = 53.9 bits (128), Expect = 3e-07 Identities = 38/104 (36%), Positives = 50/104 (48%) Frame = +3 Query: 195 DRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEHVQREIMNHRSLKHPNII 374 D Y V IG G++ K T +AVK I++ K D + EI+ R +HPNII Sbjct: 416 DGYVVKETIGVGSYSECKRCVHKATNMEYAVKVIDKS-KRDPSEEIEILL-RYGQHPNII 473 Query: 375 RFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFFH 506 K+V H+ +V E GGEL +I FSE E F H Sbjct: 474 TLKDVYDDGKHVYLVTELMRGGELLDKILRQKFFSEREASFVLH 517 Score = 46.6 bits (109), Expect = 5e-05 Identities = 25/108 (23%), Positives = 59/108 (54%), Gaps = 8/108 (7%) Frame = +3 Query: 201 YEVVRDIGSGNFGVAKLVRDVRTREH---FAVKFIERG-----HKIDEHVQREIMNHRSL 356 +E+++ +G G+FG LVR V + +A+K +++ ++ ++R+I+ + Sbjct: 62 FELLKVLGQGSFGKVFLVRKVTRPDSGHLYAMKVLKKATLKVRDRVRTKMERDIL--ADV 119 Query: 357 KHPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 HP +++ T L +++++ GG+LF R+ F+E++ +F+ Sbjct: 120 NHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFY 167
>KPK19_ARATH (Q39030) Serine/threonine-protein kinase AtPK19 (EC 2.7.11.1)| (Ribosomal-protein S6 kinase homolog) Length = 471 Score = 53.9 bits (128), Expect = 3e-07 Identities = 32/109 (29%), Positives = 57/109 (52%), Gaps = 6/109 (5%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVK------FIERGHKIDEHVQREIMNHRS 353 ++ +EV++ +G G FG VR T E +A+K +E+ H +R+I+ Sbjct: 137 IEDFEVLKVVGQGAFGKVYQVRKKDTSEIYAMKVMRKDKIVEKNHAEYMKAERDILT--K 194 Query: 354 LKHPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 + HP I++ K T L +V+++ +GG LF ++ + G F ED R + Sbjct: 195 IDHPFIVQLKYSFQTKYRLYLVLDFINGGHLFFQLYHQGLFREDLARVY 243
>KS6A_CAEEL (Q21734) Putative ribosomal protein S6 kinase alpha (EC 2.7.11.1)| Length = 784 Score = 53.9 bits (128), Expect = 3e-07 Identities = 31/109 (28%), Positives = 63/109 (57%), Gaps = 8/109 (7%) Frame = +3 Query: 198 RYEVVRDIGSGNFGVAKLVRDVRTREH---FAVKFIERGH-KIDEH----VQREIMNHRS 353 ++E+++ +G G+FG LVR VR R+ +A+K +++ K+ + ++R I+ H Sbjct: 103 QFELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVLKKATLKVRDRQRTKLERNILAH-- 160 Query: 354 LKHPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 + HP I++ T L +++++ GG+LF R+ F+ED+ +F+ Sbjct: 161 ISHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEDDVKFY 209 Score = 38.9 bits (89), Expect(2) = 1e-04 Identities = 24/90 (26%), Positives = 44/90 (48%) Frame = +3 Query: 195 DRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEHVQREIMNHRSLKHPNII 374 D YE++ IG+G V + TR +AVK +++ D + +I+ S H ++ Sbjct: 452 DDYEILEKIGNGAHSVVHKCQMKATRRKYAVKIVKKA-VFDATEEVDILLRHS-HHQFVV 509 Query: 375 RFKEVVLTPTHLAIVMEYASGGELFQRICN 464 + +V T + ++ E GGEL ++ N Sbjct: 510 KLFDVYEDETAIYMIEELCEGGELLDKLVN 539 Score = 25.4 bits (54), Expect(2) = 1e-04 Identities = 9/20 (45%), Positives = 13/20 (65%) Frame = +2 Query: 497 LLPQLISGVSYCHSMQVCHR 556 ++ L++ V Y HS QV HR Sbjct: 552 IMANLLNAVQYLHSQQVAHR 571
>KCC2D_RAT (P15791) Calcium/calmodulin-dependent protein kinase type II delta| chain (EC 2.7.11.17) (CaM-kinase II delta chain) (CaM kinase II delta subunit) (CaMK-II delta subunit) Length = 533 Score = 52.0 bits (123), Expect(2) = 4e-07 Identities = 29/99 (29%), Positives = 49/99 (49%), Gaps = 3/99 (3%) Frame = +3 Query: 195 DRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIER---GHKIDEHVQREIMNHRSLKHP 365 D Y++ ++G G F V + + T + +A K I + + ++RE R LKHP Sbjct: 12 DEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHP 71 Query: 366 NIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSE 482 NI+R + + +V + +GGELF+ I +SE Sbjct: 72 NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSE 110 Score = 21.2 bits (43), Expect(2) = 4e-07 Identities = 6/19 (31%), Positives = 12/19 (63%) Frame = +2 Query: 500 LPQLISGVSYCHSMQVCHR 556 + Q++ V++CH + HR Sbjct: 117 IQQILESVNHCHLNGIVHR 135
>KCC2A_MOUSE (P11798) Calcium/calmodulin-dependent protein kinase type II alpha| chain (EC 2.7.11.17) (CaM-kinase II alpha chain) (CaM kinase II alpha subunit) (CaMK-II alpha subunit) Length = 478 Score = 49.3 bits (116), Expect(2) = 4e-07 Identities = 27/99 (27%), Positives = 48/99 (48%), Gaps = 3/99 (3%) Frame = +3 Query: 195 DRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIER---GHKIDEHVQREIMNHRSLKHP 365 + Y++ ++G G F V + V + + K I + + ++RE R LKHP Sbjct: 11 EEYQLFEELGKGAFSVVRRCVKVLAGQEYPAKIINTKKLSARDHQKLEREARICRLLKHP 70 Query: 366 NIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSE 482 NI+R + + H ++ + +GGELF+ I +SE Sbjct: 71 NIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSE 109 Score = 23.9 bits (50), Expect(2) = 4e-07 Identities = 8/19 (42%), Positives = 12/19 (63%) Frame = +2 Query: 500 LPQLISGVSYCHSMQVCHR 556 + Q++ V +CH M V HR Sbjct: 116 IQQILEAVLHCHQMGVVHR 134
>PRKY_HUMAN (O43930) Serine/threonine-protein kinase PRKY (EC 2.7.11.1)| Length = 277 Score = 53.5 bits (127), Expect = 4e-07 Identities = 32/98 (32%), Positives = 48/98 (48%), Gaps = 4/98 (4%) Frame = +3 Query: 219 IGSGNFGVAKLVRDVRTREHFAVKFIERG----HKIDEHVQREIMNHRSLKHPNIIRFKE 386 +G+G FG LV++ + FA+K + K ++HV E + + HP +IR Sbjct: 55 MGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRRKQEQHVHNEKSVLKEVSHPFLIRLFW 114 Query: 387 VVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 L ++MEY GGELF + N G FS G F+ Sbjct: 115 TWHEERFLYMLMEYVPGGELFSYLRNRGHFSSTTGLFY 152
>MYLK_HUMAN (Q15746) Myosin light chain kinase, smooth muscle and non-muscle| isozymes (EC 2.7.11.18) (MLCK) [Contains: Telokin (Kinase-related protein) (KRP)] Length = 1914 Score = 53.5 bits (127), Expect = 4e-07 Identities = 29/89 (32%), Positives = 51/89 (57%), Gaps = 1/89 (1%) Frame = +3 Query: 195 DRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIER-GHKIDEHVQREIMNHRSLKHPNI 371 D Y++ +GSG FG + + +TR+ +A KF + K E++++EI L HP + Sbjct: 1462 DFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCLHHPKL 1521 Query: 372 IRFKEVVLTPTHLAIVMEYASGGELFQRI 458 ++ + ++ +V+E SGGELF+RI Sbjct: 1522 VQCVDAFEEKANIVMVLEIVSGGELFERI 1550
>IPL1_YARLI (Q6C3J2) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 371 Score = 53.5 bits (127), Expect = 4e-07 Identities = 29/109 (26%), Positives = 58/109 (53%), Gaps = 4/109 (3%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEHVQ----REIMNHRSLK 359 +D +E+ + +G G FG LV+D +T A+K +E+ ++ +V+ RE+ +L+ Sbjct: 96 LDDFEIGKALGKGKFGKVYLVKDKKTGFVSALKCMEKKELVEGNVEKQFRREVEIQSNLR 155 Query: 360 HPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFFH 506 H N++R + +++EY GEL++ + N RF+E + + Sbjct: 156 HTNVLRLFGHFHDKDRVYLILEYVVHGELYKLLRNQKRFTESTASSYIY 204
>PRKX_MOUSE (Q922R0) Serine/threonine-protein kinase PRKX (EC 2.7.11.1)| (PKA-related protein kinase) Length = 355 Score = 53.5 bits (127), Expect = 4e-07 Identities = 31/104 (29%), Positives = 53/104 (50%), Gaps = 4/104 (3%) Frame = +3 Query: 201 YEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKI----DEHVQREIMNHRSLKHPN 368 ++ + +G+G FG LV++ R++ A+K + I ++HVQ E + + HP Sbjct: 46 WDTIATVGTGTFGRVNLVKEKTGRQYCALKIMSIPDVIRLKQEQHVQNEKAVLKEINHPF 105 Query: 369 IIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 +I+ L ++ME+ GGELF + N GRFS F+ Sbjct: 106 LIKLLWTGHDNRFLYMLMEFVPGGELFTYLRNRGRFSSVASVFY 149
>YP150_YEAST (Q12152) Putative serine/threonine-protein kinase YPL150W (EC| 2.7.11.1) Length = 901 Score = 50.8 bits (120), Expect(2) = 5e-07 Identities = 26/93 (27%), Positives = 47/93 (50%) Frame = +3 Query: 201 YEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEHVQREIMNHRSLKHPNIIRF 380 Y++++ IG G+FG L T +K ++ D ++ RE+ HR P I + Sbjct: 41 YKILKQIGEGSFGKVYLALHRPTHRKVCLKTSDKN---DPNIVREVFYHRQFDFPYITKL 97 Query: 381 KEVVLTPTHLAIVMEYASGGELFQRICNAGRFS 479 EV++T + + + +EY G EL+ + + R S Sbjct: 98 YEVIVTESKVWMALEYCPGKELYDHLLSLRRIS 130 Score = 21.9 bits (45), Expect(2) = 5e-07 Identities = 9/20 (45%), Positives = 10/20 (50%) Frame = +2 Query: 497 LLPQLISGVSYCHSMQVCHR 556 L Q+ V Y HSM HR Sbjct: 137 LFAQISGAVYYAHSMHCVHR 156
>CDC22_ORYSA (P29619) Cell division control protein 2 homolog 2 (EC 2.7.11.22)| Length = 292 Score = 43.1 bits (100), Expect(2) = 5e-07 Identities = 30/83 (36%), Positives = 44/83 (53%), Gaps = 4/83 (4%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEHVQ----REIMNHRSLK 359 M++YE V IG G +GV + T E A+K I R + DE V REI + ++ Sbjct: 1 MEQYEKVEKIGEGTYGVVYKGKHRHTNETIALKKI-RLEQEDEGVPSTAIREISLLKEMQ 59 Query: 360 HPNIIRFKEVVLTPTHLAIVMEY 428 H NI+R ++VV + +V EY Sbjct: 60 HRNIVRLQDVVHKEKCIYLVFEY 82 Score = 29.6 bits (65), Expect(2) = 5e-07 Identities = 11/22 (50%), Positives = 16/22 (72%) Frame = +2 Query: 491 KVLLPQLISGVSYCHSMQVCHR 556 K L Q++ G++YCHS +V HR Sbjct: 104 KSFLYQILRGIAYCHSHRVLHR 125
>KCC2B_HUMAN (Q13554) Calcium/calmodulin-dependent protein kinase type II beta| chain (EC 2.7.11.17) (CaM-kinase II beta chain) (CaM kinase II beta subunit) (CaMK-II beta subunit) Length = 664 Score = 48.5 bits (114), Expect(2) = 6e-07 Identities = 30/99 (30%), Positives = 47/99 (47%), Gaps = 3/99 (3%) Frame = +3 Query: 195 DRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIER---GHKIDEHVQREIMNHRSLKHP 365 D Y++ DIG G F V + + T +A K I + + ++RE R LKH Sbjct: 12 DEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHS 71 Query: 366 NIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSE 482 NI+R + + +V + +GGELF+ I +SE Sbjct: 72 NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSE 110 Score = 23.9 bits (50), Expect(2) = 6e-07 Identities = 8/19 (42%), Positives = 12/19 (63%) Frame = +2 Query: 500 LPQLISGVSYCHSMQVCHR 556 + Q++ V +CH M V HR Sbjct: 117 IQQILEAVLHCHQMGVVHR 135
>KCC2B_RAT (P08413) Calcium/calmodulin-dependent protein kinase type II beta| chain (EC 2.7.11.17) (CaM-kinase II beta chain) (CaM kinase II beta subunit) (CaMK-II beta subunit) Length = 542 Score = 48.5 bits (114), Expect(2) = 6e-07 Identities = 30/99 (30%), Positives = 47/99 (47%), Gaps = 3/99 (3%) Frame = +3 Query: 195 DRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIER---GHKIDEHVQREIMNHRSLKHP 365 D Y++ DIG G F V + + T +A K I + + ++RE R LKH Sbjct: 12 DEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHS 71 Query: 366 NIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSE 482 NI+R + + +V + +GGELF+ I +SE Sbjct: 72 NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSE 110 Score = 23.9 bits (50), Expect(2) = 6e-07 Identities = 8/19 (42%), Positives = 12/19 (63%) Frame = +2 Query: 500 LPQLISGVSYCHSMQVCHR 556 + Q++ V +CH M V HR Sbjct: 117 IQQILEAVLHCHQMGVVHR 135
>KCC2B_MOUSE (P28652) Calcium/calmodulin-dependent protein kinase type II beta| chain (EC 2.7.11.17) (CaM-kinase II beta chain) (CaM kinase II beta subunit) (CaMK-II beta subunit) Length = 542 Score = 48.5 bits (114), Expect(2) = 6e-07 Identities = 30/99 (30%), Positives = 47/99 (47%), Gaps = 3/99 (3%) Frame = +3 Query: 195 DRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIER---GHKIDEHVQREIMNHRSLKHP 365 D Y++ DIG G F V + + T +A K I + + ++RE R LKH Sbjct: 12 DEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHS 71 Query: 366 NIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSE 482 NI+R + + +V + +GGELF+ I +SE Sbjct: 72 NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSE 110 Score = 23.9 bits (50), Expect(2) = 6e-07 Identities = 8/19 (42%), Positives = 12/19 (63%) Frame = +2 Query: 500 LPQLISGVSYCHSMQVCHR 556 + Q++ V +CH M V HR Sbjct: 117 IQQILEAVLHCHQMGVVHR 135
>CDPK_SOYBN (P28583) Calcium-dependent protein kinase SK5 (EC 2.7.11.1) (CDPK)| Length = 508 Score = 50.4 bits (119), Expect(2) = 6e-07 Identities = 37/100 (37%), Positives = 49/100 (49%), Gaps = 6/100 (6%) Frame = +3 Query: 201 YEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKID----EHVQREI--MNHRSLKH 362 YEV R +G G FG + FA K I + + E V REI M+H S +H Sbjct: 34 YEVGRKLGQGQFGTTFECTRRASGGKFACKSIPKRKLLCKEDYEDVWREIQIMHHLS-EH 92 Query: 363 PNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSE 482 N++R + T + +VME GGELF RI G +SE Sbjct: 93 ANVVRIEGTYEDSTAVHLVMELCEGGELFDRIVQKGHYSE 132 Score = 21.9 bits (45), Expect(2) = 6e-07 Identities = 8/20 (40%), Positives = 12/20 (60%) Frame = +2 Query: 497 LLPQLISGVSYCHSMQVCHR 556 L+ ++ V CHS+ V HR Sbjct: 138 LIKTIVEVVEACHSLGVMHR 157
>KCC2D_HUMAN (Q13557) Calcium/calmodulin-dependent protein kinase type II delta| chain (EC 2.7.11.17) (CaM-kinase II delta chain) (CaM kinase II delta subunit) (CaMK-II delta subunit) Length = 499 Score = 51.2 bits (121), Expect(2) = 6e-07 Identities = 29/99 (29%), Positives = 49/99 (49%), Gaps = 3/99 (3%) Frame = +3 Query: 195 DRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIER---GHKIDEHVQREIMNHRSLKHP 365 D Y++ ++G G F V + + T + +A K I + + ++RE R LKHP Sbjct: 12 DEYQLFEELGKGAFSVVRRCMKIPTGQGYAAKIINTKKLSARDHQKLEREARICRLLKHP 71 Query: 366 NIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSE 482 NI+R + + +V + +GGELF+ I +SE Sbjct: 72 NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSE 110 Score = 21.2 bits (43), Expect(2) = 6e-07 Identities = 6/19 (31%), Positives = 12/19 (63%) Frame = +2 Query: 500 LPQLISGVSYCHSMQVCHR 556 + Q++ V++CH + HR Sbjct: 117 IQQILESVNHCHLNGIVHR 135
>KS6AA_XENLA (P10665) Ribosomal protein S6 kinase 2 alpha (EC 2.7.11.1)| (Ribosomal protein S6 kinase II alpha) (S6KII-alpha) (P90-RSK) (MAP kinase-activated protein kinase 1) (MAPK-activated protein kinase 1) (MAPKAP kinase 1) (MAPKAPK-1) Length = 733 Score = 52.8 bits (125), Expect = 7e-07 Identities = 38/99 (38%), Positives = 49/99 (49%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEHVQREIMNHRSLKHPNI 371 MD Y V IG G++ V K T +AVK I++ K D + EI+ R +HPNI Sbjct: 413 MDVYTVRETIGVGSYSVCKRCVHKGTNMEYAVKVIDKT-KRDPSEEIEILR-RYGQHPNI 470 Query: 372 IRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDE 488 I K+V + +V E GGEL RI FSE E Sbjct: 471 IALKDVYKEGNSIYVVTELMRGGELLDRILRQKFFSERE 509 Score = 44.7 bits (104), Expect = 2e-04 Identities = 24/108 (22%), Positives = 58/108 (53%), Gaps = 8/108 (7%) Frame = +3 Query: 201 YEVVRDIGSGNFGVAKLVRDVR---TREHFAVKFIERG-----HKIDEHVQREIMNHRSL 356 + +++ +G G+FG LVR + + +A+K +++ ++ ++R+I+ + Sbjct: 62 FVLLKVLGQGSFGKVFLVRKITPPDANQLYAMKVLKKATLKVRDRVRTKMERDIL--ADV 119 Query: 357 KHPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 HP ++R T L +++++ GG+LF R+ F+E++ +F+ Sbjct: 120 HHPFVVRLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFY 167
>KIN4_YEAST (Q01919) Serine/threonine-protein kinase KIN4 (EC 2.7.11.1)| Length = 800 Score = 47.0 bits (110), Expect(2) = 8e-07 Identities = 33/104 (31%), Positives = 49/104 (47%), Gaps = 10/104 (9%) Frame = +3 Query: 201 YEVVRDIGSGNFGVAKL-----VRDVRTREHFAVKFIERG---HKIDEHVQ--REIMNHR 350 Y + +G G FG KL + A+K I R D+ ++ REI + Sbjct: 46 YIIGSTLGEGEFGKVKLGWTKASSSNEVPKQVAIKLIRRDTIKKDADKEIKIYREINALK 105 Query: 351 SLKHPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSE 482 L HPNII +EV+ ++ IV+E+ SGGE ++ I R E Sbjct: 106 HLTHPNIIYLEEVLQNSKYIGIVLEFVSGGEFYKYIQRKRRLKE 149 Score = 25.0 bits (53), Expect(2) = 8e-07 Identities = 11/20 (55%), Positives = 13/20 (65%) Frame = +2 Query: 497 LLPQLISGVSYCHSMQVCHR 556 L QLISGV+Y H + HR Sbjct: 155 LFAQLISGVNYMHYKGLVHR 174
>KAPC_DICDI (P34099) cAMP-dependent protein kinase catalytic subunit (EC| 2.7.11.11) Length = 648 Score = 52.4 bits (124), Expect = 9e-07 Identities = 25/107 (23%), Positives = 55/107 (51%), Gaps = 4/107 (3%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKID----EHVQREIMNHRSLK 359 + ++ +R +G+G FG L+++ + ++A+K + + + + EH+ E S+ Sbjct: 333 LKEFKQIRVLGTGTFGKVYLIQNTKDGCYYAMKCLNKAYVVQLKQVEHLNSEKSILSSIH 392 Query: 360 HPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFF 500 HP I+ + L ++ EY +GGE+F + + +FS +F+ Sbjct: 393 HPFIVNLYQAFQDEKKLYLLFEYVAGGEVFTHLRKSMKFSNSTAKFY 439
>KIN1_SCHPO (P22987) Protein kinase kin1 (EC 2.7.11.1)| Length = 891 Score = 52.4 bits (124), Expect = 9e-07 Identities = 32/122 (26%), Positives = 54/122 (44%), Gaps = 22/122 (18%) Frame = +3 Query: 201 YEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHK----------------IDEHVQR 332 Y + + IG+G+ G K+ ++T E FA+K + R H + Sbjct: 125 YVLGKTIGAGSMGKVKVAHHLKTGEQFAIKIVTRLHPDITKAKAAASAEATKAAQSEKNK 184 Query: 333 EIMNHRS------LKHPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGR 494 EI R L+HP I ++V +T +H +V E+ GG++ I + G+ E + R Sbjct: 185 EIRTVREAALSTLLRHPYICEARDVYITNSHYYMVFEFVDGGQMLDYIISHGKLKEKQAR 244 Query: 495 FF 500 F Sbjct: 245 KF 246
>KK31_SCHPO (Q9HFF4) Probable serine/threonine-protein kinase C110.01 (EC| 2.7.11.1) Length = 1023 Score = 43.1 bits (100), Expect(2) = 1e-06 Identities = 30/106 (28%), Positives = 50/106 (47%), Gaps = 12/106 (11%) Frame = +3 Query: 201 YEVVRDIGSGNFGVAKLVRDV--------RTREHFAVKFI--ERGHKIDEHVQREIMNHR 350 Y + R IG+G FG KL + R+ +K + + + + RE+ + Sbjct: 492 YILGRTIGTGEFGKVKLGWPLPKANSTIHRSTPQVVIKIVLSTKQNCQTSRLMREVAILK 551 Query: 351 SL--KHPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSE 482 L HP+I+++ + V T H IV++Y +GGELF I R + Sbjct: 552 GLGNNHPHIVKYLDFVKTKHHFGIVLDYVNGGELFDYILARRRLED 597 Score = 28.5 bits (62), Expect(2) = 1e-06 Identities = 13/20 (65%), Positives = 14/20 (70%) Frame = +2 Query: 497 LLPQLISGVSYCHSMQVCHR 556 L QLISGV+Y HS V HR Sbjct: 603 LFAQLISGVAYLHSRGVVHR 622
>M3K6_HUMAN (O95382) Mitogen-activated protein kinase kinase kinase 6 (EC| 2.7.11.25) Length = 1011 Score = 50.4 bits (119), Expect(2) = 1e-06 Identities = 32/98 (32%), Positives = 47/98 (47%), Gaps = 2/98 (2%) Frame = +3 Query: 219 IGSGNFGVAKLVRDVRTREHFAVKFI-ERGHKIDEHVQREIMNHRSLKHPNIIRFKEVVL 395 +G G +GV RD TR A+K I ER + + + EI HR L+H NI+R+ Sbjct: 377 LGKGTYGVVYAGRDRHTRVRIAIKEIPERDSRFSQPLHEEIALHRRLRHKNIVRYLGSAS 436 Query: 396 TPTHLAIVMEYASGGELFQRICNA-GRFSEDEGRFFFH 506 +L I ME GG L + + G ++E F+ Sbjct: 437 QGGYLKIFMEEVPGGSLSSLLRSVWGPLKDNESTISFY 474 Score = 21.2 bits (43), Expect(2) = 1e-06 Identities = 6/17 (35%), Positives = 10/17 (58%) Frame = +2 Query: 506 QLISGVSYCHSMQVCHR 556 Q++ G+ Y H + HR Sbjct: 477 QILQGLGYLHDNHIVHR 493
>POLO_DROME (P52304) Serine/threonine-protein kinase polo (EC 2.7.11.21)| Length = 576 Score = 48.1 bits (113), Expect(2) = 1e-06 Identities = 30/106 (28%), Positives = 48/106 (45%), Gaps = 4/106 (3%) Frame = +3 Query: 201 YEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERG----HKIDEHVQREIMNHRSLKHPN 368 Y+ +R G G F + DV T + FA K + + H E +EI HRSL HPN Sbjct: 25 YKRMRFFGKGGFAKCYEIIDVETDDVFAGKIVSKKLMIKHNQKEKTAQEITIHRSLNHPN 84 Query: 369 IIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFFH 506 I++F ++ IV+E + + +E E R++ + Sbjct: 85 IVKFHNYFEDSQNIYIVLELCKKRSMMELHKRRKSITEFECRYYIY 130 Score = 23.5 bits (49), Expect(2) = 1e-06 Identities = 8/17 (47%), Positives = 11/17 (64%) Frame = +2 Query: 506 QLISGVSYCHSMQVCHR 556 Q+I GV Y H ++ HR Sbjct: 131 QIIQGVKYLHDNRIIHR 147
>KCC2A_DROME (Q00168) Calcium/calmodulin-dependent protein kinase type II alpha| chain (EC 2.7.11.17) (CaM-kinase II alpha chain) Length = 530 Score = 49.3 bits (116), Expect(2) = 1e-06 Identities = 29/99 (29%), Positives = 47/99 (47%), Gaps = 3/99 (3%) Frame = +3 Query: 195 DRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGH---KIDEHVQREIMNHRSLKHP 365 D Y++ ++G G F + K T FA K I + + ++RE R L HP Sbjct: 12 DNYDIKEELGKGAFSIVKRCVQKSTGFEFAAKIINTKKLTARDFQKLEREARICRKLHHP 71 Query: 366 NIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSE 482 NI+R + + + +V + +GGELF+ I +SE Sbjct: 72 NIVRLHDSIQEENYHYLVFDLVTGGELFEDIVAREFYSE 110 Score = 22.3 bits (46), Expect(2) = 1e-06 Identities = 7/19 (36%), Positives = 12/19 (63%) Frame = +2 Query: 500 LPQLISGVSYCHSMQVCHR 556 + Q++ V++CH V HR Sbjct: 117 IQQILESVNHCHQNGVVHR 135
>CDC2H_PLAVI (Q9XZD6) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (Pvcrk2) Length = 288 Score = 40.8 bits (94), Expect(2) = 1e-06 Identities = 29/83 (34%), Positives = 44/83 (53%), Gaps = 4/83 (4%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEHVQ----REIMNHRSLK 359 M++Y + IG G +GV ++ E FA+K I R K DE + REI + LK Sbjct: 1 MEKYHGLEKIGEGTYGVVYKAQN-NYGETFALKKI-RLEKEDEGIPSTAIREISILKELK 58 Query: 360 HPNIIRFKEVVLTPTHLAIVMEY 428 H NI++ +V+ T L +V E+ Sbjct: 59 HSNIVKLYDVIHTKKRLILVFEH 81 Score = 30.8 bits (68), Expect(2) = 1e-06 Identities = 12/22 (54%), Positives = 16/22 (72%) Frame = +2 Query: 491 KVLLPQLISGVSYCHSMQVCHR 556 K L QL+SG++YCH +V HR Sbjct: 103 KSFLLQLLSGIAYCHEHRVLHR 124
>CDC2H_PLAKH (O96821) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 288 Score = 40.8 bits (94), Expect(2) = 1e-06 Identities = 29/83 (34%), Positives = 44/83 (53%), Gaps = 4/83 (4%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEHVQ----REIMNHRSLK 359 M++Y + IG G +GV ++ E FA+K I R K DE + REI + LK Sbjct: 1 MEKYHGLEKIGEGTYGVVYKAQN-NYGETFALKKI-RLEKEDEGIPSTAIREISILKELK 58 Query: 360 HPNIIRFKEVVLTPTHLAIVMEY 428 H NI++ +V+ T L +V E+ Sbjct: 59 HSNIVKLYDVIHTKKRLILVFEH 81 Score = 30.8 bits (68), Expect(2) = 1e-06 Identities = 12/22 (54%), Positives = 16/22 (72%) Frame = +2 Query: 491 KVLLPQLISGVSYCHSMQVCHR 556 K L QL+SG++YCH +V HR Sbjct: 103 KSFLLQLLSGIAYCHEHRVLHR 124
>ICK_HUMAN (Q9UPZ9) Serine/threonine-protein kinase ICK (EC 2.7.11.22)| (Intestinal cell kinase) (hICK) (MAK-related kinase) (MRK) (Laryngeal cancer kinase 2) (LCK2) Length = 632 Score = 52.0 bits (123), Expect = 1e-06 Identities = 26/81 (32%), Positives = 43/81 (53%), Gaps = 2/81 (2%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHKIDEHVQ--REIMNHRSLKHP 365 M+RY +R +G G +G L R + + E A+K ++R E RE+ + + L H Sbjct: 1 MNRYTTIRQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNLREVKSLKKLNHA 60 Query: 366 NIIRFKEVVLTPTHLAIVMEY 428 N+++ KEV+ HL + EY Sbjct: 61 NVVKLKEVIRENDHLYFIFEY 81
>AURKC_HUMAN (Q9UQB9) Serine/threonine-protein kinase 13 (EC 2.7.11.1)| (Aurora/Ipl1/Eg2 protein 2) (Aurora/Ipl1-related kinase 3) (Aurora-C) Length = 309 Score = 47.4 bits (111), Expect(2) = 1e-06 Identities = 27/101 (26%), Positives = 50/101 (49%), Gaps = 4/101 (3%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGH----KIDEHVQREIMNHRSLK 359 +D +E+ R +G G FG L R + A+K + + ++ ++REI L+ Sbjct: 40 VDDFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQ 99 Query: 360 HPNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSE 482 HPNI+R + +++EYA GEL++ + + + E Sbjct: 100 HPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDE 140 Score = 23.9 bits (50), Expect(2) = 1e-06 Identities = 7/20 (35%), Positives = 13/20 (65%) Frame = +2 Query: 497 LLPQLISGVSYCHSMQVCHR 556 ++ +L ++YCH +V HR Sbjct: 146 IIEELADALTYCHDKKVIHR 165
>CDK2_XENLA (P23437) Cell division protein kinase 2 (EC 2.7.11.22) (CDC2| homolog Eg1 protein kinase) Length = 297 Score = 43.5 bits (101), Expect(2) = 1e-06 Identities = 26/82 (31%), Positives = 41/82 (50%), Gaps = 3/82 (3%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFIERGHK---IDEHVQREIMNHRSLKH 362 M+ ++ V IG G +GV R+ T E A+K I + + REI + L H Sbjct: 1 MENFQKVEKIGEGTYGVVYKARNRETGEIVALKKIRLDTETEGVPSTAIREISLLKELNH 60 Query: 363 PNIIRFKEVVLTPTHLAIVMEY 428 PNI++ +V+ T L +V E+ Sbjct: 61 PNIVKLLDVIHTENKLYLVFEF 82 Score = 27.7 bits (60), Expect(2) = 1e-06 Identities = 11/22 (50%), Positives = 16/22 (72%) Frame = +2 Query: 491 KVLLPQLISGVSYCHSMQVCHR 556 K L QL+ G+++CHS +V HR Sbjct: 105 KSYLFQLLQGLAFCHSHRVLHR 126
>CDK5_RAT (Q03114) Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein| kinase II catalytic subunit) (TPKII catalytic subunit) (Serine/threonine-protein kinase PSSALRE) Length = 292 Score = 42.0 bits (97), Expect(2) = 1e-06 Identities = 24/82 (29%), Positives = 40/82 (48%), Gaps = 3/82 (3%) Frame = +3 Query: 192 MDRYEVVRDIGSGNFGVAKLVRDVRTREHFAVKFI---ERGHKIDEHVQREIMNHRSLKH 362 M +YE + IG G +G ++ T E A+K + + + REI + LKH Sbjct: 1 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH 60 Query: 363 PNIIRFKEVVLTPTHLAIVMEY 428 NI+R +V+ + L +V E+ Sbjct: 61 KNIVRLHDVLHSDKKLTLVFEF 82 Score = 29.3 bits (64), Expect(2) = 1e-06 Identities = 12/22 (54%), Positives = 15/22 (68%) Frame = +2 Query: 491 KVLLPQLISGVSYCHSMQVCHR 556 K LL QL+ G+ +CHS V HR Sbjct: 104 KSLLFQLLKGLGFCHSRNVLHR 125 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 68,414,385 Number of Sequences: 219361 Number of extensions: 1256481 Number of successful extensions: 6492 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 5125 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5849 length of database: 80,573,946 effective HSP length: 106 effective length of database: 57,321,680 effective search space used: 4528412720 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
