ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | bart27c12 |
|---|---|
| Clone Library Name | barley_pub |
>CDC2D_ANTMA (Q38775) Cell division control protein 2 homolog D (EC 2.7.11.22)| (EC 2.7.11.23) Length = 312 Score = 212 bits (539), Expect = 7e-55 Identities = 103/131 (78%), Positives = 115/131 (87%) Frame = +3 Query: 165 AMDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLS 344 AMD + KLEKVGEGTYGKVY+A EK+TG+IVALKKTRL ED+EGVPPT LREVSLLRMLS Sbjct: 10 AMDAFVKLEKVGEGTYGKVYRAMEKSTGKIVALKKTRLHEDEEGVPPTTLREVSLLRMLS 69 Query: 345 QDPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQL 524 +DPHVVRLLD+KQGQNKEG+T+LYLVFEYMDTDLKK+IR +Q + I VK LMYQL Sbjct: 70 RDPHVVRLLDVKQGQNKEGKTVLYLVFEYMDTDLKKYIRSFKQTGESIAPMNVKSLMYQL 129 Query: 525 CKGVAFCHGRG 557 CKGVAFCHG G Sbjct: 130 CKGVAFCHGHG 140
>CDC2C_ANTMA (Q38774) Cell division control protein 2 homolog C (EC 2.7.11.22)| (EC 2.7.11.23) Length = 305 Score = 167 bits (423), Expect = 2e-41 Identities = 85/133 (63%), Positives = 105/133 (78%), Gaps = 3/133 (2%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 M+ YEKLEKVGEGTYGKVYKA EK+TG++VALKKTRL D+EGVPPTALREVSLL+MLSQ Sbjct: 1 MEKYEKLEKVGEGTYGKVYKALEKSTGQVVALKKTRLEMDEEGVPPTALREVSLLQMLSQ 60 Query: 348 DPHVVRLLDLKQGQ-NKEGQTILYLVFEYMDTDLKKFIRGHRQ--NHQKIPAHTVKILMY 518 +VVRLL ++ K G+ +LYLVFEY+DTDLKKFI HR+ N + +P ++ ++ Sbjct: 61 SLYVVRLLSVEHVDCAKNGKPLLYLVFEYLDTDLKKFIDSHRKGPNPRPLPPQQIQSFLF 120 Query: 519 QLCKGVAFCHGRG 557 QLCKGV+ CH G Sbjct: 121 QLCKGVSHCHAHG 133
>CDC2B_ARATH (P25859) Cell division control protein 2 homolog B (EC 2.7.11.22)| (EC 2.7.11.23) Length = 309 Score = 155 bits (392), Expect = 7e-38 Identities = 81/137 (59%), Positives = 104/137 (75%), Gaps = 7/137 (5%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 M+ YEKLEKVGEGTYGKVYKA EK TG++VALKKTRL D+EG+PPTALRE+SLL+MLS Sbjct: 1 MEKYEKLEKVGEGTYGKVYKAMEKGTGKLVALKKTRLEMDEEGIPPTALREISLLQMLST 60 Query: 348 DPHVVRLLDLK-----QGQNKEGQTILYLVFEYMDTDLKKFIRGHRQ--NHQKIPAHTVK 506 +VVRLL ++ +++ ++ LYLVFEY+DTDLKKFI +R+ N + + ++ Sbjct: 61 SIYVVRLLCVEHVHQPSTKSQSTKSNLYLVFEYLDTDLKKFIDSYRKGPNPKPLEPFLIQ 120 Query: 507 ILMYQLCKGVAFCHGRG 557 LM+QLCKGVA CH G Sbjct: 121 KLMFQLCKGVAHCHSHG 137
>CDK2_XENLA (P23437) Cell division protein kinase 2 (EC 2.7.11.22) (CDC2| homolog Eg1 protein kinase) Length = 297 Score = 124 bits (312), Expect = 1e-28 Identities = 67/127 (52%), Positives = 91/127 (71%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 M+ ++K+EK+GEGTYG VYKAR + TG IVALKK RL + EGVP TA+RE+SLL+ L+ Sbjct: 1 MENFQKVEKIGEGTYGVVYKARNRETGEIVALKKIRLDTETEGVPSTAIREISLLKELNH 60 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 P++V+LLD+ +NK LYLVFE+++ DLKKF+ G N I VK ++QL Sbjct: 61 -PNIVKLLDVIHTENK-----LYLVFEFLNQDLKKFMDG--SNISGISLALVKSYLFQLL 112 Query: 528 KGVAFCH 548 +G+AFCH Sbjct: 113 QGLAFCH 119
>CDK3_HUMAN (Q00526) Cell division protein kinase 3 (EC 2.7.11.22)| Length = 305 Score = 124 bits (312), Expect = 1e-28 Identities = 63/127 (49%), Positives = 92/127 (72%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 MD+++K+EK+GEGTYG VYKA+ + TG++VALKK RL + EGVP TA+RE+SLL+ L + Sbjct: 1 MDMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKEL-K 59 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 P++VRLLD+ + K LYLVFE++ DLKK++ ++P H +K ++QL Sbjct: 60 HPNIVRLLDVVHNERK-----LYLVFEFLSQDLKKYM--DSTPGSELPLHLIKSYLFQLL 112 Query: 528 KGVAFCH 548 +GV+FCH Sbjct: 113 QGVSFCH 119
>CDC2_DICDI (P34112) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) Length = 296 Score = 124 bits (312), Expect = 1e-28 Identities = 71/128 (55%), Positives = 91/128 (71%), Gaps = 3/128 (2%) Frame = +3 Query: 177 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 356 Y+KLEK+GEGTYGKVYKA+EKATGR+VALKK RL +D+GVP TALRE+SLL+ + P+ Sbjct: 10 YQKLEKLGEGTYGKVYKAKEKATGRMVALKKIRL--EDDGVPSTALREISLLKEVPH-PN 66 Query: 357 VVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPA---HTVKILMYQLC 527 VV L D+ QN+ LYLVFEY+D DLKK++ +PA +K +YQL Sbjct: 67 VVSLFDVLHCQNR-----LYLVFEYLDQDLKKYM-------DSVPALCPQLIKSYLYQLL 114 Query: 528 KGVAFCHG 551 KG+A+ HG Sbjct: 115 KGLAYSHG 122
>CDC22_XENLA (P24033) Cell division control protein 2 homolog 2 (EC 2.7.11.22)| (EC 2.7.11.23) (p34 protein kinase 2) Length = 302 Score = 124 bits (310), Expect = 2e-28 Identities = 64/130 (49%), Positives = 90/130 (69%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 MD Y K+EK+GEGTYG VYK R KATG++VA+KK RL ++EGVP TA+RE+SLL+ L Q Sbjct: 1 MDEYTKIEKIGEGTYGVVYKGRHKATGQVVAMKKIRLENEEEGVPSTAIREISLLKEL-Q 59 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 P++V LLD+ ++ LYL+FE++ D+KK++ + Q I VK +YQ+ Sbjct: 60 HPNIVCLLDVLMQDSR-----LYLIFEFLSMDVKKYL-DSIPSGQYIDTMLVKSYLYQIL 113 Query: 528 KGVAFCHGRG 557 +G+ FCH RG Sbjct: 114 QGIVFCHSRG 123
>CDC2A_ARATH (P24100) Cell division control protein 2 homolog A (EC 2.7.11.22)| (EC 2.7.11.23) Length = 294 Score = 123 bits (308), Expect = 4e-28 Identities = 62/127 (48%), Positives = 88/127 (69%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 MD YEK+EK+GEGTYG VYKAR+K T +ALKK RL ++DEGVP TA+RE+SLL+ + Q Sbjct: 1 MDQYEKVEKIGEGTYGVVYKARDKVTNETIALKKIRLEQEDEGVPSTAIREISLLKEM-Q 59 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 ++V+L D+ + + LYLVFEY+D DLKK + + + H +K +YQ+ Sbjct: 60 HSNIVKLQDVVHSEKR-----LYLVFEYLDLDLKKHMDSTPDFSKDL--HMIKTYLYQIL 112 Query: 528 KGVAFCH 548 +G+A+CH Sbjct: 113 RGIAYCH 119
>CDC21_XENLA (P35567) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| (EC 2.7.11.23) (p34 protein kinase 1) Length = 302 Score = 122 bits (307), Expect = 5e-28 Identities = 64/129 (49%), Positives = 89/129 (68%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 MD Y K+EK+GEGTYG VYK R KATG++VA+KK RL ++EGVP TA+RE+SLL+ L Q Sbjct: 1 MDEYTKIEKIGEGTYGVVYKGRHKATGQVVAMKKIRLENEEEGVPSTAIREISLLKEL-Q 59 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 P++V LLD+ ++ LYL+FE++ DLKK++ + Q I VK +YQ+ Sbjct: 60 HPNIVCLLDVLMQDSR-----LYLIFEFLSMDLKKYL-DSIPSGQYIDTMLVKSYLYQIL 113 Query: 528 KGVAFCHGR 554 +G+ FCH R Sbjct: 114 QGIVFCHSR 122
>CDK2_HUMAN (P24941) Cell division protein kinase 2 (EC 2.7.11.22) (p33 protein| kinase) Length = 298 Score = 122 bits (306), Expect = 7e-28 Identities = 65/127 (51%), Positives = 89/127 (70%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 M+ ++K+EK+GEGTYG VYKAR K TG +VALKK RL + EGVP TA+RE+SLL+ L+ Sbjct: 1 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 P++V+LLD+ +NK LYLVFE++ DLKKF+ IP +K ++QL Sbjct: 61 -PNIVKLLDVIHTENK-----LYLVFEFLHQDLKKFMDASALT--GIPLPLIKSYLFQLL 112 Query: 528 KGVAFCH 548 +G+AFCH Sbjct: 113 QGLAFCH 119
>CDC2_CARAU (P51958) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 302 Score = 122 bits (305), Expect = 9e-28 Identities = 66/129 (51%), Positives = 90/129 (69%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 MD Y K+EK+GEGTYG VYK R K TG++VA+KK RL ++EGVP TA+RE+SLL+ L Q Sbjct: 1 MDDYLKIEKIGEGTYGVVYKGRNKTTGQVVAMKKIRLESEEEGVPSTAVREISLLKEL-Q 59 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 P+VVRLLD+ ++K LYLVFE++ DLKK++ + Q + VK +YQ+ Sbjct: 60 HPNVVRLLDVLMQESK-----LYLVFEFLSMDLKKYL-DSIPSGQFMDPMLVKSYLYQIL 113 Query: 528 KGVAFCHGR 554 +G+ FCH R Sbjct: 114 EGILFCHCR 122
>CDK2_MOUSE (P97377) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 346 Score = 121 bits (303), Expect = 2e-27 Identities = 64/127 (50%), Positives = 89/127 (70%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 M+ ++K+EK+GEGTYG VYKA+ K TG +VALKK RL + EGVP TA+RE+SLL+ L+ Sbjct: 1 MENFQKVEKIGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 P++V+LLD+ +NK LYLVFE++ DLKKF+ IP +K ++QL Sbjct: 61 -PNIVKLLDVIHTENK-----LYLVFEFLHQDLKKFMDASALT--GIPLPLIKSYLFQLL 112 Query: 528 KGVAFCH 548 +G+AFCH Sbjct: 113 QGLAFCH 119
>CDC22_MEDSA (Q05006) Cell division control protein 2 homolog 2 (EC 2.7.11.22)| Length = 294 Score = 121 bits (303), Expect = 2e-27 Identities = 62/127 (48%), Positives = 89/127 (70%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 M+ YEK+EK+GEGTYG VYKAR++AT +ALKK RL ++DEGVP TA+RE+SLL+ + Q Sbjct: 1 MEQYEKVEKIGEGTYGVVYKARDRATNETIALKKIRLEQEDEGVPSTAIREISLLKEM-Q 59 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 ++VRL D+ + + LYLVFEY+D DLKKF+ + + +K+ +YQ+ Sbjct: 60 HRNIVRLQDVVHSEKR-----LYLVFEYLDLDLKKFMDSSPEFAK--DQRQIKMFLYQIL 112 Query: 528 KGVAFCH 548 G+A+CH Sbjct: 113 CGIAYCH 119
>CDK2_CRIGR (O55076) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 121 bits (303), Expect = 2e-27 Identities = 64/127 (50%), Positives = 89/127 (70%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 M+ ++K+EK+GEGTYG VYKA+ K TG +VALKK RL + EGVP TA+RE+SLL+ L+ Sbjct: 1 MENFQKVEKIGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 P++V+LLD+ +NK LYLVFE++ DLKKF+ IP +K ++QL Sbjct: 61 -PNIVKLLDVIHTENK-----LYLVFEFLHQDLKKFMDASAVT--GIPLPLIKSYLFQLL 112 Query: 528 KGVAFCH 548 +G+AFCH Sbjct: 113 QGLAFCH 119
>CDK2_BOVIN (Q5E9Y0) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 121 bits (303), Expect = 2e-27 Identities = 64/127 (50%), Positives = 89/127 (70%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 M+ ++K+EK+GEGTYG VYKA+ K TG +VALKK RL + EGVP TA+RE+SLL+ L+ Sbjct: 1 MENFQKVEKIGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 P++V+LLD+ +NK LYLVFE++ DLKKF+ IP +K ++QL Sbjct: 61 -PNIVKLLDVIHTENK-----LYLVFEFLHQDLKKFMDASALT--GIPLPLIKSYLFQLL 112 Query: 528 KGVAFCH 548 +G+AFCH Sbjct: 113 QGLAFCH 119
>CDC2_SCHPO (P04551) Cell division control protein 2 (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinse) Length = 297 Score = 120 bits (301), Expect = 3e-27 Identities = 65/133 (48%), Positives = 89/133 (66%), Gaps = 4/133 (3%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 M+ Y+K+EK+GEGTYG VYKAR K +GRIVA+KK RL ++ EGVP TA+RE+SLL+ ++ Sbjct: 1 MENYQKVEKIGEGTYGVVYKARHKLSGRIVAMKKIRLEDESEGVPSTAIREISLLKEVND 60 Query: 348 D---PHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFI-RGHRQNHQKIPAHTVKILM 515 + + VRLLD+ ++K LYLVFE++D DLKK++ R + V+ Sbjct: 61 ENNRSNCVRLLDILHAESK-----LYLVFEFLDMDLKKYMDRISETGATSLDPRLVQKFT 115 Query: 516 YQLCKGVAFCHGR 554 YQL GV FCH R Sbjct: 116 YQLVNGVNFCHSR 128
>CDC2_RANDY (Q9W739) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) Length = 302 Score = 120 bits (301), Expect = 3e-27 Identities = 64/129 (49%), Positives = 89/129 (68%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 MD Y K+EK+GEGTYG VYK KATG+IVA+KK RL ++EGVP TA+RE+SLL+ L Q Sbjct: 1 MDEYAKIEKIGEGTYGVVYKGVHKATGQIVAMKKIRLENEEEGVPSTAIREISLLKEL-Q 59 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 P++V LLD+ ++ LYL+FE++ DLKK++ + Q + A VK +YQ+ Sbjct: 60 HPNIVCLLDVLMQDSR-----LYLIFEFLSMDLKKYL-DSIPSGQYLEAMLVKSYLYQIL 113 Query: 528 KGVAFCHGR 554 +G+ FCH R Sbjct: 114 QGIIFCHAR 122
>CDC2A_ANTMA (Q38772) Cell division control protein 2 homolog A (EC 2.7.11.22)| (EC 2.7.11.23) Length = 294 Score = 120 bits (301), Expect = 3e-27 Identities = 62/127 (48%), Positives = 88/127 (69%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 M+ YEK+EK+GEGTYG VYKAR++ T +ALKK RL ++DEGVP TA+RE+SLL+ + Q Sbjct: 1 MEQYEKVEKIGEGTYGVVYKARDRVTNETIALKKIRLEQEDEGVPSTAIREISLLKEM-Q 59 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 ++VRL D+ + + LYLVFEY+D DLKK + + Q VK+ +YQ+ Sbjct: 60 HGNIVRLQDVVHSEKR-----LYLVFEYLDLDLKKHMDSCPEFSQ--DPRLVKMFLYQIL 112 Query: 528 KGVAFCH 548 +G+A+CH Sbjct: 113 RGIAYCH 119
>CDK2_RAT (Q63699) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 120 bits (301), Expect = 3e-27 Identities = 63/127 (49%), Positives = 89/127 (70%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 M+ ++K+EK+GEGTYG VYKA+ K TG +VALKK RL + EGVP TA+RE+SLL+ L+ Sbjct: 1 MENFQKVEKIGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 P++V+LLD+ +NK LYLVFE++ DLKKF+ +P +K ++QL Sbjct: 61 -PNIVKLLDVIHTENK-----LYLVFEFLHQDLKKFMDASALT--GLPLPLIKSYLFQLL 112 Query: 528 KGVAFCH 548 +G+AFCH Sbjct: 113 QGLAFCH 119
>CDC2_CHERU (P93101) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) Length = 294 Score = 120 bits (300), Expect = 3e-27 Identities = 64/127 (50%), Positives = 88/127 (69%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 MD YEK+EK+GEGTYG VYKAR+K T +ALKK RL ++DEGVP TA+RE+SLL+ + Q Sbjct: 1 MDQYEKVEKIGEGTYGVVYKARDKVTNETIALKKIRLEQEDEGVPSTAIREISLLKEM-Q 59 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 ++VRL D+ + + LYLVFEY+D DLKK + + K P +K +YQ+ Sbjct: 60 HGNIVRLQDVVHSEKR-----LYLVFEYLDLDLKKHM-DSCPDFAKDP-RMIKRFLYQIL 112 Query: 528 KGVAFCH 548 +G+A+CH Sbjct: 113 RGIAYCH 119
>CDC2H_DICDI (P34117) CDC2-like serine/threonine-protein kinase CRP (EC| 2.7.11.22) (EC 2.7.11.23) Length = 292 Score = 119 bits (299), Expect = 4e-27 Identities = 67/127 (52%), Positives = 88/127 (69%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 M+ Y K+EK+GEGTYG V KA+ + TG IVALK+ RL +DEGVP TA+RE+SLL+ L + Sbjct: 1 MEKYSKIEKLGEGTYGIVNKAKNRETGEIVALKRIRLDSEDEGVPCTAIREISLLKEL-K 59 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 P++VRL D+ + K L LVFEY+D DLKK++ + +I T+K MYQL Sbjct: 60 HPNIVRLHDVIHTERK-----LTLVFEYLDQDLKKYL---DECGGEISKPTIKSFMYQLL 111 Query: 528 KGVAFCH 548 KGVAFCH Sbjct: 112 KGVAFCH 118
>CDK2_MESAU (P48963) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 119 bits (299), Expect = 4e-27 Identities = 64/127 (50%), Positives = 88/127 (69%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 M+ ++K+EK+GEGTYG VYKA+ K TG +VALKK RL + EGVP TA+RE+SLL+ L+ Sbjct: 1 MENFQKVEKIGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 P++V+LLD+ +NK LYLVFE + DLKKF+ IP +K ++QL Sbjct: 61 -PNIVKLLDVIHTENK-----LYLVFELLHQDLKKFMDASAVT--GIPLPLIKSYLFQLL 112 Query: 528 KGVAFCH 548 +G+AFCH Sbjct: 113 QGLAFCH 119
>CDC28_YEAST (P00546) Cell division control protein 28 (EC 2.7.11.22)| Length = 298 Score = 119 bits (298), Expect = 6e-27 Identities = 66/127 (51%), Positives = 89/127 (70%), Gaps = 3/127 (2%) Frame = +3 Query: 177 YEKLEKVGEGTYGKVYKAREKATG---RIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 Y++LEKVGEGTYG VYKA + G R+VALKK RL +DEGVP TA+RE+SLL+ L + Sbjct: 8 YKRLEKVGEGTYGVVYKALDLRPGQGQRVVALKKIRLESEDEGVPSTAIREISLLKEL-K 66 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 D ++VRL D+ + LYLVFE++D DLK+++ G ++ Q + A VK M QLC Sbjct: 67 DDNIVRLYDIVHSDAHK----LYLVFEFLDLDLKRYMEGIPKD-QPLGADIVKKFMMQLC 121 Query: 528 KGVAFCH 548 KG+A+CH Sbjct: 122 KGIAYCH 128
>CDC2_ORYLU (Q9DG98) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 119 bits (297), Expect = 8e-27 Identities = 63/129 (48%), Positives = 89/129 (68%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 M+ Y K+EK+GEGTYG VYK R K+TG++VA+KK RL ++EGVP TA+REVSLL+ L + Sbjct: 1 MEDYVKIEKIGEGTYGVVYKGRHKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQEL-K 59 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 P+VVRLLD+ +++ LYL+FE++ DLKK++ P VK +YQ+ Sbjct: 60 HPNVVRLLDVLMQESR-----LYLIFEFLSMDLKKYLDSIPSGQYMDPM-LVKSYLYQIL 113 Query: 528 KGVAFCHGR 554 +G+ FCH R Sbjct: 114 EGIYFCHRR 122
>CDC2_ORYLA (Q9DGD3) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 119 bits (297), Expect = 8e-27 Identities = 63/129 (48%), Positives = 89/129 (68%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 M+ Y K+EK+GEGTYG VYK R K+TG++VA+KK RL ++EGVP TA+REVSLL+ L + Sbjct: 1 MEDYVKIEKIGEGTYGVVYKGRHKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQEL-K 59 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 P+VVRLLD+ +++ LYL+FE++ DLKK++ P VK +YQ+ Sbjct: 60 HPNVVRLLDVLMQESR-----LYLIFEFLSMDLKKYLDSIPSGQYMDPM-LVKSYLYQIL 113 Query: 528 KGVAFCHGR 554 +G+ FCH R Sbjct: 114 EGIYFCHRR 122
>CDC2_ORYJA (Q9DGA2) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 119 bits (297), Expect = 8e-27 Identities = 63/129 (48%), Positives = 89/129 (68%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 M+ Y K+EK+GEGTYG VYK R K+TG++VA+KK RL ++EGVP TA+REVSLL+ L + Sbjct: 1 MEDYVKIEKIGEGTYGVVYKGRHKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQEL-K 59 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 P+VVRLLD+ +++ LYL+FE++ DLKK++ P VK +YQ+ Sbjct: 60 HPNVVRLLDVLMQESR-----LYLIFEFLSMDLKKYLDSIPSGQYMDPM-LVKSYLYQIL 113 Query: 528 KGVAFCHGR 554 +G+ FCH R Sbjct: 114 EGIYFCHRR 122
>CDC2_ORYCU (Q9DGA5) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 119 bits (297), Expect = 8e-27 Identities = 63/129 (48%), Positives = 89/129 (68%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 M+ Y K+EK+GEGTYG VYK R K+TG++VA+KK RL ++EGVP TA+REVSLL+ L + Sbjct: 1 MEDYVKIEKIGEGTYGVVYKGRHKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQEL-K 59 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 P+VVRLLD+ +++ LYL+FE++ DLKK++ P VK +YQ+ Sbjct: 60 HPNVVRLLDVLMQESR-----LYLIFEFLSMDLKKYLDSIPSGQYMDPM-LVKSYLYQIL 113 Query: 528 KGVAFCHGR 554 +G+ FCH R Sbjct: 114 EGIYFCHRR 122
>CDC2_VIGAC (Q41639) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) Length = 294 Score = 118 bits (296), Expect = 1e-26 Identities = 64/134 (47%), Positives = 89/134 (66%), Gaps = 7/134 (5%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 M+ YEK+EK+GEGTYG VYKAR++ T +ALKK RL ++DEGVP TA+RE+SLL+ + Q Sbjct: 1 MEQYEKVEKIGEGTYGVVYKARDRVTNETIALKKIRLEQEDEGVPSTAIREISLLKEM-Q 59 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKK-------FIRGHRQNHQKIPAHTVK 506 ++VRL D+ + + LYLVFEY+D DLKK F++ RQ VK Sbjct: 60 HRNIVRLQDVVHSEKR-----LYLVFEYLDLDLKKHMDSSPEFVKDPRQ---------VK 105 Query: 507 ILMYQLCKGVAFCH 548 + +YQ+ G+A+CH Sbjct: 106 MFLYQILCGIAYCH 119
>CDC2_VIGUN (P52389) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) Length = 294 Score = 118 bits (295), Expect = 1e-26 Identities = 64/134 (47%), Positives = 89/134 (66%), Gaps = 7/134 (5%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 M+ YEK+EK+GEGTYG VYKAR++ T +ALKK RL ++DEGVP TA+RE+SLL+ + Q Sbjct: 1 MEQYEKVEKIGEGTYGVVYKARDRVTDETIALKKIRLEQEDEGVPSTAIREISLLKEM-Q 59 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKK-------FIRGHRQNHQKIPAHTVK 506 ++VRL D+ + + LYLVFEY+D DLKK F++ RQ VK Sbjct: 60 HRNIVRLQDVVHSEKR-----LYLVFEYLDLDLKKHMDSSPEFVKDPRQ---------VK 105 Query: 507 ILMYQLCKGVAFCH 548 + +YQ+ G+A+CH Sbjct: 106 MFLYQILCGIAYCH 119
>CDC2_MAIZE (P23111) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) Length = 294 Score = 117 bits (293), Expect = 2e-26 Identities = 63/127 (49%), Positives = 88/127 (69%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 M+ YEK+EK+GEGTYG VYKA +KAT +ALKK RL ++DEGVP TA+RE+SLL+ ++ Sbjct: 1 MEQYEKVEKIGEGTYGVVYKALDKATNETIALKKIRLEQEDEGVPSTAIREISLLKEMNH 60 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 ++VRL D+ + + +YLVFEY+D DLKKF+ + K P +K +YQ+ Sbjct: 61 G-NIVRLHDVVHSEKR-----IYLVFEYLDLDLKKFMDSCPE-FAKNPT-LIKSYLYQIL 112 Query: 528 KGVAFCH 548 GVA+CH Sbjct: 113 HGVAYCH 119
>CDK3_MOUSE (Q80YP0) Truncated cell division protein kinase 3 homolog| Length = 186 Score = 116 bits (291), Expect = 4e-26 Identities = 61/127 (48%), Positives = 90/127 (70%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 MD+++K+EK+GEGTYG VYKAR K TG++VALKK RL + EGVP TA+RE+SLL+ L + Sbjct: 1 MDVFQKVEKIGEGTYGVVYKARNKVTGQLVALKKIRLDLEAEGVPSTAVREISLLKEL-K 59 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 P++++LLD+ + K LY+VFE++ DLK+ + + ++P VK + QL Sbjct: 60 HPNIIKLLDVVHREKK-----LYMVFEFLTQDLKRHMDSSPTS--ELPLPVVKSYLAQLL 112 Query: 528 KGVAFCH 548 +GV+FCH Sbjct: 113 EGVSFCH 119
>CDK2_CARAU (P43450) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 116 bits (290), Expect = 5e-26 Identities = 62/127 (48%), Positives = 87/127 (68%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 M+ ++K+EK+GEGTYG VYKA+ K TG VALKK RL + EGVP TA+RE+SLL+ L+ Sbjct: 1 MESFQKVEKIGEGTYGVVYKAKNKVTGETVALKKIRLDTETEGVPSTAIREISLLKELNH 60 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 P++V+L D+ +NK LYLVFE++ DLK+F+ +P VK ++QL Sbjct: 61 -PNIVKLHDVIHTENK-----LYLVFEFLHQDLKRFMDSSTVTGISLP--LVKSYLFQLL 112 Query: 528 KGVAFCH 548 +G+AFCH Sbjct: 113 QGLAFCH 119
>CDC21_ORYSA (P29618) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| Length = 294 Score = 115 bits (289), Expect = 6e-26 Identities = 62/127 (48%), Positives = 87/127 (68%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 M+ YEK EK+GEGTYG VY+AR+K T +ALKK RL ++DEGVP TA+RE+SLL+ + Sbjct: 1 MEQYEKEEKIGEGTYGVVYRARDKVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMHH 60 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 ++VRL D+ + + +YLVFEY+D DLKKF+ + K P +K +YQ+ Sbjct: 61 G-NIVRLHDVIHSEKR-----IYLVFEYLDLDLKKFMDSCPE-FAKNPT-LIKSYLYQIL 112 Query: 528 KGVAFCH 548 +GVA+CH Sbjct: 113 RGVAYCH 119
>CDC2_HUMAN (P06493) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 115 bits (288), Expect = 8e-26 Identities = 59/129 (45%), Positives = 87/129 (67%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 M+ Y K+EK+GEGTYG VYK R K TG++VA+KK RL ++EGVP TA+RE+SLL+ L + Sbjct: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKEL-R 59 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 P++V L D+ ++ LYL+FE++ DLKK++ Q + + VK +YQ+ Sbjct: 60 HPNIVSLQDVLMQDSR-----LYLIFEFLSMDLKKYLDSIPPG-QYMDSSLVKSYLYQIL 113 Query: 528 KGVAFCHGR 554 +G+ FCH R Sbjct: 114 QGIVFCHSR 122
>CDK5_XENLA (P51166) Cell division protein kinase 5 (EC 2.7.11.22) (Neuronal| cyclin-dependent kinase 5) Length = 292 Score = 115 bits (287), Expect = 1e-25 Identities = 65/129 (50%), Positives = 83/129 (64%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 M YEKLEK+GEGTYG V+KA+ + T IVALK+ RL +DDEGVP +ALRE+ LL+ L + Sbjct: 1 MQKYEKLEKIGEGTYGTVFKAKNRDTHEIVALKRVRLDDDDEGVPSSALREICLLKEL-K 59 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 ++VRL D+ K L LVFE+ D DLKK+ + + VK MYQL Sbjct: 60 HKNIVRLHDVLHSDKK-----LTLVFEFCDQDLKKYFDSCNGD---LDPEIVKSFMYQLL 111 Query: 528 KGVAFCHGR 554 KG+AFCH R Sbjct: 112 KGLAFCHSR 120
>CDC2_BOVIN (P48734) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 115 bits (287), Expect = 1e-25 Identities = 59/129 (45%), Positives = 87/129 (67%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 M+ Y K+EK+GEGTYG VYK R K TG++VA+KK RL ++EGVP TA+RE+SLL+ L + Sbjct: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKEL-R 59 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 P++V L D+ ++ LYL+FE++ DLKK++ Q + + VK +YQ+ Sbjct: 60 HPNIVSLQDVLMQDSR-----LYLIFEFLSMDLKKYLDSIPPG-QFMDSSLVKSYLYQIL 113 Query: 528 KGVAFCHGR 554 +G+ FCH R Sbjct: 114 QGIVFCHSR 122
>CDC2_PONPY (Q5RCH1) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 114 bits (284), Expect = 2e-25 Identities = 58/129 (44%), Positives = 86/129 (66%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 M+ Y K+EK+GEGTYG VYK R K TG++V +KK RL ++EGVP TA+RE+SLL+ L + Sbjct: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVTMKKIRLESEEEGVPSTAIREISLLKEL-R 59 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 P++V L D+ ++ LYL+FE++ DLKK++ Q + + VK +YQ+ Sbjct: 60 HPNIVSLQDVLMQDSR-----LYLIFEFLSMDLKKYLDSIPPG-QYMDSSLVKSYLYQIL 113 Query: 528 KGVAFCHGR 554 +G+ FCH R Sbjct: 114 QGIVFCHSR 122
>CDC2_RAT (P39951) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 113 bits (283), Expect = 3e-25 Identities = 59/129 (45%), Positives = 87/129 (67%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 M+ Y K+EK+GEGTYG VYK R + TG+IVA+KK RL ++EGVP TA+RE+SLL+ L + Sbjct: 1 MEDYIKIEKIGEGTYGVVYKGRHRTTGQIVAMKKIRLESEEEGVPSTAIREISLLKEL-R 59 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 P++V L D+ ++ LYL+FE++ DLKK++ Q + + VK +YQ+ Sbjct: 60 HPNIVSLQDVLMQDSR-----LYLIFEFLSMDLKKYLDSIPPG-QFMDSSLVKSYLYQIL 113 Query: 528 KGVAFCHGR 554 +G+ FCH R Sbjct: 114 QGIVFCHSR 122
>CDC22_ORYSA (P29619) Cell division control protein 2 homolog 2 (EC 2.7.11.22)| Length = 292 Score = 113 bits (282), Expect = 4e-25 Identities = 60/128 (46%), Positives = 84/128 (65%), Gaps = 1/128 (0%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 M+ YEK+EK+GEGTYG VYK + + T +ALKK RL ++DEGVP TA+RE+SLL+ + Q Sbjct: 1 MEQYEKVEKIGEGTYGVVYKGKHRHTNETIALKKIRLEQEDEGVPSTAIREISLLKEM-Q 59 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAH-TVKILMYQL 524 ++VRL D+ + +YLVFEY+D DLKK H + H VK +YQ+ Sbjct: 60 HRNIVRLQDVVHKEK-----CIYLVFEYLDLDLKK----HMDSSPDFKNHRIVKSFLYQI 110 Query: 525 CKGVAFCH 548 +G+A+CH Sbjct: 111 LRGIAYCH 118
>CDC2_CHICK (P13863) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 112 bits (281), Expect = 5e-25 Identities = 59/129 (45%), Positives = 85/129 (65%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 M+ Y K+EK+GEGTYG VYK R K TG++VA+KK RL ++EGVP TA+RE+SLL+ L Sbjct: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKEL-H 59 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 P++V L D+ + LYL+FE++ DLKK++ + Q + VK +YQ+ Sbjct: 60 HPNIVCLQDVLMQDAR-----LYLIFEFLSMDLKKYL-DTIPSGQYLDRSRVKSYLYQIL 113 Query: 528 KGVAFCHGR 554 +G+ FCH R Sbjct: 114 QGIVFCHSR 122
>CDK5_RAT (Q03114) Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein| kinase II catalytic subunit) (TPKII catalytic subunit) (Serine/threonine-protein kinase PSSALRE) Length = 292 Score = 112 bits (281), Expect = 5e-25 Identities = 63/129 (48%), Positives = 83/129 (64%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 M YEKLEK+GEGTYG V+KA+ + T IVALK+ RL +DDEGVP +ALRE+ LL+ L + Sbjct: 1 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKEL-K 59 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 ++VRL D+ K L LVFE+ D DLKK+ + + VK L++QL Sbjct: 60 HKNIVRLHDVLHSDKK-----LTLVFEFCDQDLKKYFDSCNGD---LDPEIVKSLLFQLL 111 Query: 528 KGVAFCHGR 554 KG+ FCH R Sbjct: 112 KGLGFCHSR 120
>CDC21_MEDSA (P24923) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| (EC 2.7.11.23) (Fragment) Length = 291 Score = 111 bits (278), Expect = 1e-24 Identities = 62/130 (47%), Positives = 84/130 (64%), Gaps = 7/130 (5%) Frame = +3 Query: 180 EKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPHV 359 E +EK+GEGTYG VYKAR++ T +ALKK RL ++DEGVP TA+RE+SLL+ + Q ++ Sbjct: 2 ENVEKIGEGTYGVVYKARDRVTNETIALKKIRLEQEDEGVPSTAIREISLLKEM-QHRNI 60 Query: 360 VRLLDLKQGQNKEGQTILYLVFEYMDTDLKK-------FIRGHRQNHQKIPAHTVKILMY 518 VRL D+ + LYLVFEY+D DLKK FI+ RQ VK+ +Y Sbjct: 61 VRLQDVVHSDKR-----LYLVFEYLDLDLKKHMDSSPEFIKDPRQ---------VKMFLY 106 Query: 519 QLCKGVAFCH 548 Q+ G+A+CH Sbjct: 107 QMLCGIAYCH 116
>CDC2_MOUSE (P11440) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 111 bits (278), Expect = 1e-24 Identities = 58/129 (44%), Positives = 87/129 (67%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 M+ Y K+EK+GEGTYG VYK R + TG+IVA+KK RL ++EGVP TA+RE+SLL+ L + Sbjct: 1 MEDYIKIEKIGEGTYGVVYKGRHRVTGQIVAMKKIRLESEEEGVPSTAIREISLLKEL-R 59 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 P++V L D+ ++ LYL+FE++ DLKK++ Q + + VK ++Q+ Sbjct: 60 HPNIVSLQDVLMQDSR-----LYLIFEFLSMDLKKYLDSIPPG-QFMDSSLVKSYLHQIL 113 Query: 528 KGVAFCHGR 554 +G+ FCH R Sbjct: 114 QGIVFCHSR 122
>CRK1_LEIME (Q06309) Cell division protein kinase 2 homolog CRK1 (EC 2.7.11.23)| Length = 301 Score = 111 bits (278), Expect = 1e-24 Identities = 60/126 (47%), Positives = 86/126 (68%) Frame = +3 Query: 177 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 356 YE+ EK+GEGTYG VYKAR+ +T VALK+ RL ++EGVP TA+RE+SLL+ L + + Sbjct: 5 YERQEKIGEGTYGVVYKARDTSTAATVALKRIRLDSEEEGVPCTAIREISLLKELRHE-N 63 Query: 357 VVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLCKGV 536 +V+LLD+ +++ L +VFEY+D DLKK++ N + A T++ M L +GV Sbjct: 64 IVKLLDVCHSEHR-----LTIVFEYLDLDLKKYLDRENGN---LDAATIQHFMRDLLRGV 115 Query: 537 AFCHGR 554 AFCH R Sbjct: 116 AFCHQR 121
>CDK5_MOUSE (P49615) Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein| kinase II catalytic subunit) (TPKII catalytic subunit) (Serine/threonine-protein kinase PSSALRE) (CRK6) Length = 292 Score = 111 bits (277), Expect = 2e-24 Identities = 62/129 (48%), Positives = 82/129 (63%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 M YEKLEK+GEGTYG V+KA+ + T IVALK+ RL +DDEGVP +ALRE+ LL+ L + Sbjct: 1 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKEL-K 59 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 ++VRL D+ K L LVFE+ D DLKK+ + + VK ++QL Sbjct: 60 HKNIVRLHDVLHSDKK-----LTLVFEFCDQDLKKYFDSCNGD---LDPEIVKSFLFQLL 111 Query: 528 KGVAFCHGR 554 KG+ FCH R Sbjct: 112 KGLGFCHSR 120
>CDK5_HUMAN (Q00535) Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein| kinase II catalytic subunit) (TPKII catalytic subunit) (Serine/threonine-protein kinase PSSALRE) Length = 292 Score = 111 bits (277), Expect = 2e-24 Identities = 62/129 (48%), Positives = 82/129 (63%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 M YEKLEK+GEGTYG V+KA+ + T IVALK+ RL +DDEGVP +ALRE+ LL+ L + Sbjct: 1 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKEL-K 59 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 ++VRL D+ K L LVFE+ D DLKK+ + + VK ++QL Sbjct: 60 HKNIVRLHDVLHSDKK-----LTLVFEFCDQDLKKYFDSCNGD---LDPEIVKSFLFQLL 111 Query: 528 KGVAFCHGR 554 KG+ FCH R Sbjct: 112 KGLGFCHSR 120
>CDK5_BOVIN (Q02399) Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein| kinase II catalytic subunit) (TPKII catalytic subunit) (Proline-directed protein kinase 33 kDa subunit) (PDPK) Length = 292 Score = 111 bits (277), Expect = 2e-24 Identities = 62/129 (48%), Positives = 82/129 (63%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 M YEKLEK+GEGTYG V+KA+ + T IVALK+ RL +DDEGVP +ALRE+ LL+ L + Sbjct: 1 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKEL-K 59 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 ++VRL D+ K L LVFE+ D DLKK+ + + VK ++QL Sbjct: 60 HKNIVRLHDVLHSDKK-----LTLVFEFCDQDLKKYFDSCNGD---LDPEIVKSFLFQLL 111 Query: 528 KGVAFCHGR 554 KG+ FCH R Sbjct: 112 KGLGFCHSR 120
>CC2H3_TRYBB (P54666) Cell division control protein 2 homolog 3 (EC 2.7.11.22)| Length = 311 Score = 111 bits (277), Expect = 2e-24 Identities = 60/126 (47%), Positives = 85/126 (67%) Frame = +3 Query: 171 DLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQD 350 D Y +++ +GEGTYG VY+A ++ATG+IVALKK RL DEG+P TALREVS+L+ + Sbjct: 21 DRYNRMDILGEGTYGVVYRAVDRATGQIVALKKVRLDRTDEGIPQTALREVSILQEI-HH 79 Query: 351 PHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLCK 530 P++V LLD+ K LYL+FEY+D DLKK + + T+K ++YQL + Sbjct: 80 PNIVNLLDVICADGK-----LYLIFEYVDHDLKKAL---EKRGGAFTGTTLKKIIYQLLE 131 Query: 531 GVAFCH 548 G++FCH Sbjct: 132 GLSFCH 137
>CDC2_DROME (P23572) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) Length = 297 Score = 110 bits (276), Expect = 2e-24 Identities = 57/129 (44%), Positives = 87/129 (67%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 M+ +EK+EK+GEGTYG VYK R + TG+IVA+KK RL DDEGVP TA+RE+SLL+ L Sbjct: 1 MEDFEKIEKIGEGTYGVVYKGRNRLTGQIVAMKKIRLESDDEGVPSTAIREISLLKELKH 60 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 + ++V L D+ +N+ +YL+FE++ DLKK++ + + + + V+ +YQ+ Sbjct: 61 E-NIVCLEDVLMEENR-----IYLIFEFLSMDLKKYMDSLPVD-KHMESELVRSYLYQIT 113 Query: 528 KGVAFCHGR 554 + FCH R Sbjct: 114 SAILFCHRR 122
>CDC2_EMENI (Q00646) Cell division control protein 2 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent protein kinase) Length = 323 Score = 108 bits (271), Expect = 8e-24 Identities = 66/144 (45%), Positives = 89/144 (61%), Gaps = 17/144 (11%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKA-TGRIVALKKTRLPEDDEGVPPTALREVSLLRMLS 344 M+ Y+K+EK+GEGTYG VYKARE RIVALKK RL +DEGVP TA+RE+SLL+ ++ Sbjct: 1 MENYQKIEKIGEGTYGVVYKARELTHPNRIVALKKIRLEAEDEGVPSTAIREISLLKEMN 60 Query: 345 QDPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFI---------RGHR-------QN 476 DP++VRLL++ + LYLVFE++D DLKK++ RG Sbjct: 61 -DPNIVRLLNIVHADGHK----LYLVFEFLDLDLKKYMEALPVSEGGRGRALPDGSTLSR 115 Query: 477 HQKIPAHTVKILMYQLCKGVAFCH 548 + + VK M QL +G+ FCH Sbjct: 116 NLGLGDAMVKKFMAQLIEGIRFCH 139
>PHO85_CANAL (Q9HGY5) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) (CaPHO85) Length = 326 Score = 108 bits (269), Expect = 1e-23 Identities = 59/124 (47%), Positives = 82/124 (66%) Frame = +3 Query: 177 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 356 +++LEK+GEGTY VYK R +ATG +VALK+ L + +EG P TA+RE+SL++ L + + Sbjct: 8 FQQLEKLGEGTYATVYKGRNRATGALVALKEISL-DSEEGTPSTAIREISLMKELDHE-N 65 Query: 357 VVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLCKGV 536 +V L D+ +NK L LVFEYMD DLKK++ H Q + VK M+QL KG+ Sbjct: 66 IVTLYDVIHTENK-----LTLVFEYMDKDLKKYMEVHGQ-QSALDLKVVKSFMFQLLKGI 119 Query: 537 AFCH 548 FCH Sbjct: 120 MFCH 123
>CDC2_AJECA (P54119) Cell division control protein 2 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent protein kinase) Length = 324 Score = 107 bits (268), Expect = 2e-23 Identities = 65/145 (44%), Positives = 88/145 (60%), Gaps = 18/145 (12%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKA-TGRIVALKKTRLPEDDEGVPPTALREVSLLRMLS 344 M+ Y+K+EK+GEGTYG VYKAR+ RIVALKK RL +DEGVP TA+RE+SLL+ + Sbjct: 1 MENYQKIEKIGEGTYGVVYKARDLTHPNRIVALKKIRLEAEDEGVPSTAIREISLLKEM- 59 Query: 345 QDPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFI------RGHR-----------Q 473 DP++VRLL++ + LYLVFE++D DLKK++ G R Sbjct: 60 HDPNIVRLLNIVHADGHK----LYLVFEFLDLDLKKYMEALPVSEGGRGKALPDGSTLDM 115 Query: 474 NHQKIPAHTVKILMYQLCKGVAFCH 548 N + VK M QL +G+ +CH Sbjct: 116 NRLGLGEAMVKKFMAQLVEGIRYCH 140
>PEF1_SCHPO (O74456) Serine/threonine-protein kinase pef1 (EC 2.7.11.22)| (Cyclin-dependent kinase pef1) (PHO85 homolog) Length = 288 Score = 107 bits (266), Expect = 3e-23 Identities = 59/124 (47%), Positives = 83/124 (66%) Frame = +3 Query: 177 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 356 Y++LEK+GEGTY VYK + + TG IVALK R+ + DEG P TA+RE+SL++ L + P+ Sbjct: 3 YQRLEKLGEGTYAHVYKGQNRVTGEIVALKVIRI-DADEGTPSTAIREISLMKEL-RHPN 60 Query: 357 VVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLCKGV 536 ++ L D+ Q +NK L LVFEYM+ DLKK++ + N +P VK QL KG+ Sbjct: 61 IMSLSDVLQTENK-----LMLVFEYMEKDLKKYMDTY-GNQGALPPSQVKNFTQQLLKGI 114 Query: 537 AFCH 548 +FCH Sbjct: 115 SFCH 118
>CDC28_CANAL (P43063) Cell division control protein 28 (EC 2.7.11.22)| Length = 317 Score = 107 bits (266), Expect = 3e-23 Identities = 60/125 (48%), Positives = 84/125 (67%), Gaps = 1/125 (0%) Frame = +3 Query: 177 YEKLEKVGEGTYGKVYKARE-KATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDP 353 Y++ EKVGEGTYG VYKA + K R+VALKK RL +DEGVP TA+RE+SLL+ + +D Sbjct: 7 YQRQEKVGEGTYGVVYKALDTKHNNRVVALKKIRLESEDEGVPSTAIREISLLKEM-KDD 65 Query: 354 HVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLCKG 533 ++VRL D+ + + LYLVFE++D DLKK++ Q + A+ +K M QL +G Sbjct: 66 NIVRLYDIIHSDSHK----LYLVFEFLDLDLKKYMESIPQG-VGLGANMIKRFMNQLIRG 120 Query: 534 VAFCH 548 + CH Sbjct: 121 IKHCH 125
>PHO85_KLULA (Q92241) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 304 Score = 107 bits (266), Expect = 3e-23 Identities = 60/126 (47%), Positives = 82/126 (65%), Gaps = 2/126 (1%) Frame = +3 Query: 177 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 356 +++LEKVG GTY VYK K TG VALK+ +L + +EG P TA+RE+SL++ L D + Sbjct: 7 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKL-DSEEGTPSTAIREISLMKELKHD-N 64 Query: 357 VVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFI--RGHRQNHQKIPAHTVKILMYQLCK 530 +VRL D+ +NK L LVFE+MD DLKKF+ R +H+ + VK +QL + Sbjct: 65 IVRLFDVIHTENK-----LTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQ 119 Query: 531 GVAFCH 548 GVAFCH Sbjct: 120 GVAFCH 125
>CC2H1_TRYCO (P54664) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| Length = 301 Score = 107 bits (266), Expect = 3e-23 Identities = 62/126 (49%), Positives = 86/126 (68%) Frame = +3 Query: 177 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 356 Y++LEK+GEG+YG VY+AR+ T IVALK+ RL +EGVP TA+RE+S+L+ L + + Sbjct: 5 YQRLEKIGEGSYGVVYRARDITTDVIVALKRIRLESVEEGVPCTAIREISILKELRHE-N 63 Query: 357 VVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLCKGV 536 +VRLLD+ +N+ L LVFEYM+ DLKK++ R + PA T++ M L KGV Sbjct: 64 IVRLLDVCHSENR-----LNLVFEYMEMDLKKYM--DRASGNLDPA-TIQEFMRSLLKGV 115 Query: 537 AFCHGR 554 FCH R Sbjct: 116 RFCHER 121
>CDK5_DROME (P48609) Cell division protein kinase 5 homolog (EC 2.7.11.22)| Length = 294 Score = 106 bits (265), Expect = 4e-23 Identities = 60/127 (47%), Positives = 81/127 (63%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 M Y+K+EK+GEGTYG V+K R + T IVALK+ RL EDDEGVP +ALRE+ LL+ L + Sbjct: 1 MQKYDKMEKIGEGTYGTVFKGRNRDTMEIVALKRVRLDEDDEGVPSSALREICLLKEL-K 59 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 ++VRL+D+ K L LVFE+ D DLKK+ + +I + M QL Sbjct: 60 HKNIVRLIDVLHSDKK-----LTLVFEHCDQDLKKYF---DSLNGEIDMAVCRSFMLQLL 111 Query: 528 KGVAFCH 548 +G+AFCH Sbjct: 112 RGLAFCH 118
>PHO85_YARLI (Q6C7U8) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 294 Score = 105 bits (261), Expect = 1e-22 Identities = 58/124 (46%), Positives = 81/124 (65%) Frame = +3 Query: 177 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 356 +++LEK+GEGTY VYK R + TG++VALK+ L + +EG P TA+RE+SL++ L + + Sbjct: 7 FQQLEKLGEGTYATVYKGRNRTTGQLVALKEINL-DSEEGTPSTAIREISLMKELKHE-N 64 Query: 357 VVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLCKGV 536 +V L D+ +NK L LVFEYMD DLKKF+ N + VK MYQL +G+ Sbjct: 65 IVTLYDVIHTENK-----LNLVFEYMDKDLKKFM-DTNGNKGALETKQVKWFMYQLLRGI 118 Query: 537 AFCH 548 FCH Sbjct: 119 LFCH 122
>CDC2C_DROME (P23573) Cell division control protein 2 cognate (EC 2.7.11.22) (EC| 2.7.11.23) Length = 314 Score = 104 bits (259), Expect = 2e-22 Identities = 57/127 (44%), Positives = 81/127 (63%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 +D +++ EK+GEGTYG VYKAR +TG+ VALKK RL + EGVP TA+RE+SLL+ L + Sbjct: 5 LDNFQRAEKIGEGTYGIVYKARSNSTGQDVALKKIRLEGETEGVPSTAIREISLLKNL-K 63 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 P+VV+L D+ N LY++FEY++ DLKK + + +K M+Q+ Sbjct: 64 HPNVVQLFDVVISGNN-----LYMIFEYLNMDLKKLM---DKKKDVFTPQLIKSYMHQIL 115 Query: 528 KGVAFCH 548 V FCH Sbjct: 116 DAVGFCH 122
>PHO85_DEBHA (Q6BRY2) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 330 Score = 103 bits (256), Expect = 4e-22 Identities = 55/124 (44%), Positives = 81/124 (65%) Frame = +3 Query: 177 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 356 +++LEK+GEGTY VYK R + G++VALK+ L + +EG P TA+RE+SL++ L + + Sbjct: 8 FQQLEKLGEGTYATVYKGRNRTNGQLVALKEINL-DSEEGTPSTAIREISLMKELDHE-N 65 Query: 357 VVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLCKGV 536 +V L D+ +NK L LVFE+MD DLKK++ H N + VK ++QL KG+ Sbjct: 66 IVTLYDVIHTENK-----LTLVFEFMDKDLKKYMEAH-GNQGALDLKIVKSFIFQLLKGI 119 Query: 537 AFCH 548 FCH Sbjct: 120 MFCH 123
>CDC2_CAEEL (P34556) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) Length = 332 Score = 102 bits (254), Expect = 7e-22 Identities = 54/126 (42%), Positives = 82/126 (65%) Frame = +3 Query: 177 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 356 + KLEK+GEGTYG VYK + + T +VA+KK RL +DEGVP TA+RE+SLL+ L Q P+ Sbjct: 22 FTKLEKIGEGTYGVVYKGKNRRTNAMVAMKKIRLESEDEGVPSTAVREISLLKEL-QHPN 80 Query: 357 VVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLCKGV 536 VV L + +N+ L+L+FE++ DLK+++ + +P T+K +Q+ + + Sbjct: 81 VVGLEAVIMQENR-----LFLIFEFLSFDLKRYM-DQLGKDEYLPLETLKSYTFQILQAM 134 Query: 537 AFCHGR 554 FCH R Sbjct: 135 CFCHQR 140
>PCTK3_RAT (O35832) Serine/threonine-protein kinase PCTAIRE-3 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 3) Length = 451 Score = 102 bits (254), Expect = 7e-22 Identities = 67/157 (42%), Positives = 91/157 (57%), Gaps = 7/157 (4%) Frame = +3 Query: 105 LQHQNQGAAAPMXXXXXXLRAMDL-------YEKLEKVGEGTYGKVYKAREKATGRIVAL 263 LQ +N G P+ D+ Y KL+K+GEGTY V+K R K T +VAL Sbjct: 90 LQLENPGLPKPLTRMSRRASLSDIGFGKLETYVKLDKLGEGTYATVFKGRSKLTENLVAL 149 Query: 264 KKTRLPEDDEGVPPTALREVSLLRMLSQDPHVVRLLDLKQGQNKEGQTILYLVFEYMDTD 443 K+ RL E +EG P TA+REVSLL+ L + ++V L DL L LVFEY+D+D Sbjct: 150 KEIRL-EHEEGAPCTAIREVSLLKDL-KHANIVTLHDLIHTDRS-----LTLVFEYLDSD 202 Query: 444 LKKFIRGHRQNHQKIPAHTVKILMYQLCKGVAFCHGR 554 LK+++ H N + H VKI M+QL +G+A+CH R Sbjct: 203 LKQYL-DHCGNLMNM--HNVKIFMFQLLRGLAYCHRR 236
>PCTK3_MOUSE (Q04899) Serine/threonine-protein kinase PCTAIRE-3 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 3) Length = 451 Score = 102 bits (254), Expect = 7e-22 Identities = 67/157 (42%), Positives = 91/157 (57%), Gaps = 7/157 (4%) Frame = +3 Query: 105 LQHQNQGAAAPMXXXXXXLRAMDL-------YEKLEKVGEGTYGKVYKAREKATGRIVAL 263 LQ +N G P+ D+ Y KL+K+GEGTY V+K R K T +VAL Sbjct: 90 LQLENPGLPKPLTRMSRRASLSDIGFGKLETYVKLDKLGEGTYATVFKGRSKLTENLVAL 149 Query: 264 KKTRLPEDDEGVPPTALREVSLLRMLSQDPHVVRLLDLKQGQNKEGQTILYLVFEYMDTD 443 K+ RL E +EG P TA+REVSLL+ L + ++V L DL L LVFEY+D+D Sbjct: 150 KEIRL-EHEEGAPCTAIREVSLLKDL-KHANIVTLHDLIHTDRS-----LTLVFEYLDSD 202 Query: 444 LKKFIRGHRQNHQKIPAHTVKILMYQLCKGVAFCHGR 554 LK+++ H N + H VKI M+QL +G+A+CH R Sbjct: 203 LKQYL-DHCGNLMNM--HNVKIFMFQLLRGLAYCHHR 236
>CC2H1_TRYBB (P38973) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| Length = 301 Score = 101 bits (252), Expect = 1e-21 Identities = 57/128 (44%), Positives = 86/128 (67%), Gaps = 2/128 (1%) Frame = +3 Query: 177 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 356 YE+L+K+GEG+YG V++AR+ TG IVA+K+ RL +++EGVP TA+RE+S+L+ L + + Sbjct: 5 YERLQKIGEGSYGVVFRARDVTTGTIVAVKRIRLEKEEEGVPCTAIREISILKELRHE-N 63 Query: 357 VVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNH--QKIPAHTVKILMYQLCK 530 +VRLLD+ + + L LVFE M+ DLKK++ +H + A T++ M L Sbjct: 64 IVRLLDVCHSEKR-----LTLVFECMEMDLKKYM-----DHVGGDLDAGTIQEFMRSLLS 113 Query: 531 GVAFCHGR 554 GV FCH R Sbjct: 114 GVRFCHER 121
>PCTK3_PONPY (Q5RD01) Serine/threonine-protein kinase PCTAIRE-3 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 3) Length = 472 Score = 101 bits (251), Expect = 2e-21 Identities = 61/129 (47%), Positives = 84/129 (65%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 ++ Y KL+K+GEGTY V+K R K T +VALK+ RL E +EG P TA+REVSLL+ L + Sbjct: 139 LETYVKLDKLGEGTYATVFKGRSKLTENLVALKEIRL-EHEEGAPCTAIREVSLLKNL-K 196 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 ++V L DL L LVFEY+D+DLK+++ H N + H VKI M+QL Sbjct: 197 HANIVTLHDLIHTDRS-----LTLVFEYLDSDLKQYL-DHCGNLMSM--HNVKIFMFQLL 248 Query: 528 KGVAFCHGR 554 +G+A+CH R Sbjct: 249 RGLAYCHHR 257
>CDC2H_THEPA (Q27032) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 298 Score = 100 bits (249), Expect = 3e-21 Identities = 57/127 (44%), Positives = 79/127 (62%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 M Y K+EK+GEGTYG VYKA+ G I ALKK R+ E+DEG+P TA+RE+SLL+ L Sbjct: 1 MRRYHKMEKIGEGTYGVVYKAQNNH-GEICALKKIRVEEEDEGIPSTAIREISLLKEL-H 58 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 P++V L D+ + L LVFEY+D DLKK + + T K +YQ+ Sbjct: 59 HPNIVWLRDVIHSEK-----CLTLVFEYLDQDLKKLLDACDGG---LEPTTAKSFLYQIL 110 Query: 528 KGVAFCH 548 +G+++CH Sbjct: 111 RGISYCH 117
>CDC2H_THEAN (Q26671) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 298 Score = 100 bits (249), Expect = 3e-21 Identities = 57/127 (44%), Positives = 79/127 (62%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 M Y K+EK+GEGTYG VYKA+ G I ALKK R+ E+DEG+P TA+RE+SLL+ L Sbjct: 1 MRRYHKMEKIGEGTYGVVYKAQNNH-GEICALKKIRVEEEDEGIPSTAIREISLLKEL-H 58 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 P++V L D+ + L LVFEY+D DLKK + + T K +YQ+ Sbjct: 59 HPNIVWLRDVIHSEK-----CLTLVFEYLDQDLKKLLDACDGG---LEPTTAKSFLYQIL 110 Query: 528 KGVAFCH 548 +G+++CH Sbjct: 111 RGISYCH 117
>PHO85_ASHGO (Q751E8) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 303 Score = 100 bits (248), Expect = 4e-21 Identities = 57/126 (45%), Positives = 82/126 (65%), Gaps = 2/126 (1%) Frame = +3 Query: 177 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 356 +++LE++G GTY VYK K TG VALK+ +L + +EG P TA+RE+SL++ L + + Sbjct: 9 FKQLERLGNGTYATVYKGLNKTTGLYVALKEVKL-DSEEGTPSTAIREISLMKELKHE-N 66 Query: 357 VVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFI--RGHRQNHQKIPAHTVKILMYQLCK 530 +VRL D+ +NK L LVFE+MD DLKKF+ R R+ + + VK +QL + Sbjct: 67 IVRLYDVIHTENK-----LTLVFEFMDNDLKKFMDSRLDREMPRGLELSLVKYFQWQLLQ 121 Query: 531 GVAFCH 548 GVAFCH Sbjct: 122 GVAFCH 127
>PHO85_CANGA (Q6FKD4) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 302 Score = 100 bits (248), Expect = 4e-21 Identities = 56/126 (44%), Positives = 82/126 (65%), Gaps = 2/126 (1%) Frame = +3 Query: 177 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 356 +++LEK+G GTY VYK K+TG VALK+ +L + +EG P TA+RE+SL++ L D + Sbjct: 6 FKQLEKLGNGTYATVYKGLNKSTGVYVALKEVKL-DSEEGTPSTAIREISLMKELKHD-N 63 Query: 357 VVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNH--QKIPAHTVKILMYQLCK 530 +VRL D+ +NK L LVFEYMD DLKK++ + + + + VK +QL + Sbjct: 64 IVRLYDVIHTENK-----LTLVFEYMDNDLKKYMDSRTVGNAPRGLEMNLVKYFQWQLLE 118 Query: 531 GVAFCH 548 G+AFCH Sbjct: 119 GLAFCH 124
>CC2H2_TRYBB (P54665) Cell division control protein 2 homolog 2 (EC 2.7.11.22)| Length = 345 Score = 99.4 bits (246), Expect = 6e-21 Identities = 58/128 (45%), Positives = 81/128 (63%) Frame = +3 Query: 171 DLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQD 350 D Y ++EKVGEG+YG VYK + TGR VA+K+ L +D GVP TA+REVSLLR L+ Sbjct: 44 DRYSRIEKVGEGSYGIVYKCHDNFTGRTVAMKRIPLIVNDGGVPSTAVREVSLLRELNH- 102 Query: 351 PHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLCK 530 P+VVRLLD+ + K L L+FEYM+ DL+ + +Q + ++ +M+QL Sbjct: 103 PYVVRLLDVVLHEAK-----LLLIFEYMEQDLQGML---KQRNTAFVGGKLRRIMFQLLL 154 Query: 531 GVAFCHGR 554 G+ CH R Sbjct: 155 GLHECHSR 162
>PCTK2_RAT (O35831) Serine/threonine-protein kinase PCTAIRE-2 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 2) Length = 523 Score = 99.4 bits (246), Expect = 6e-21 Identities = 59/129 (45%), Positives = 81/129 (62%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 M+ Y KLEK+GEGTY VYK R K T +VALK+ RL E +EG P TA+REVSLL+ L + Sbjct: 189 METYIKLEKLGEGTYATVYKGRSKLTENLVALKEIRL-EHEEGAPCTAIREVSLLKDL-K 246 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 ++V L D+ L LVFEY+D DLK+++ + H VK+ +YQ+ Sbjct: 247 HANIVTLHDIVHTDKS-----LTLVFEYLDKDLKQYM---DDCGSIMSMHNVKLFLYQIL 298 Query: 528 KGVAFCHGR 554 +G+A+CH R Sbjct: 299 RGLAYCHRR 307
>PCTK2_MOUSE (Q8K0D0) Serine/threonine-protein kinase PCTAIRE-2 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 2) Length = 523 Score = 99.4 bits (246), Expect = 6e-21 Identities = 59/129 (45%), Positives = 81/129 (62%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 M+ Y KLEK+GEGTY VYK R K T +VALK+ RL E +EG P TA+REVSLL+ L + Sbjct: 189 METYIKLEKLGEGTYATVYKGRSKLTENLVALKEIRL-EHEEGAPCTAIREVSLLKDL-K 246 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 ++V L D+ L LVFEY+D DLK+++ + H VK+ +YQ+ Sbjct: 247 HANIVTLHDIVHTDKS-----LTLVFEYLDKDLKQYM---DDCGNIMSMHNVKLFLYQIL 298 Query: 528 KGVAFCHGR 554 +G+A+CH R Sbjct: 299 RGLAYCHRR 307
>PCTK2_HUMAN (Q00537) Serine/threonine-protein kinase PCTAIRE-2 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 2) Length = 523 Score = 99.4 bits (246), Expect = 6e-21 Identities = 59/129 (45%), Positives = 81/129 (62%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 M+ Y KLEK+GEGTY VYK R K T +VALK+ RL E +EG P TA+REVSLL+ L + Sbjct: 189 METYIKLEKLGEGTYATVYKGRSKLTENLVALKEIRL-EHEEGAPCTAIREVSLLKDL-K 246 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 ++V L D+ L LVFEY+D DLK+++ + H VK+ +YQ+ Sbjct: 247 HANIVTLHDIVHTDKS-----LTLVFEYLDKDLKQYM---DDCGNIMSMHNVKLFLYQIL 298 Query: 528 KGVAFCHGR 554 +G+A+CH R Sbjct: 299 RGLAYCHRR 307
>PCTK3_HUMAN (Q07002) Serine/threonine-protein kinase PCTAIRE-3 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 3) Length = 472 Score = 99.0 bits (245), Expect = 8e-21 Identities = 60/129 (46%), Positives = 83/129 (64%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 ++ Y KL+K+GEGTY V+K R K +VALK+ RL E +EG P TA+REVSLL+ L + Sbjct: 139 LETYVKLDKLGEGTYATVFKGRSKLMENLVALKEIRL-EHEEGAPCTAIREVSLLKNL-K 196 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 ++V L DL L LVFEY+D+DLK+++ H N + H VKI M+QL Sbjct: 197 HANIVTLHDLIHTDRS-----LTLVFEYLDSDLKQYL-DHCGNLMSM--HNVKIFMFQLL 248 Query: 528 KGVAFCHGR 554 +G+A+CH R Sbjct: 249 RGLAYCHHR 257
>CDK6_MOUSE (Q64261) Cell division protein kinase 6 (EC 2.7.11.22)| (Serine/threonine-protein kinase PLSTIRE) (CRK2) Length = 326 Score = 98.2 bits (243), Expect = 1e-20 Identities = 55/132 (41%), Positives = 84/132 (63%), Gaps = 3/132 (2%) Frame = +3 Query: 162 RAMDLYEKLEKVGEGTYGKVYKARE-KATGRIVALKKTRLPEDDEGVPPTALREVSLLRM 338 RA YE + ++GEG YGKV+KAR+ K GR VALK+ R+ +EG+P + +REV++LR Sbjct: 8 RADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTSEEGMPLSTIREVAVLRH 67 Query: 339 LS--QDPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKIL 512 L + P+VVRL D+ + +T L LVFE++D DL ++ + +P T+K + Sbjct: 68 LETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYL--DKVPEPGVPTETIKDM 125 Query: 513 MYQLCKGVAFCH 548 M+QL +G+ F H Sbjct: 126 MFQLLRGLDFLH 137
>CDK6_HUMAN (Q00534) Cell division protein kinase 6 (EC 2.7.11.22)| (Serine/threonine-protein kinase PLSTIRE) Length = 326 Score = 97.8 bits (242), Expect = 2e-20 Identities = 55/132 (41%), Positives = 84/132 (63%), Gaps = 3/132 (2%) Frame = +3 Query: 162 RAMDLYEKLEKVGEGTYGKVYKARE-KATGRIVALKKTRLPEDDEGVPPTALREVSLLRM 338 RA YE + ++GEG YGKV+KAR+ K GR VALK+ R+ +EG+P + +REV++LR Sbjct: 8 RADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLRH 67 Query: 339 LS--QDPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKIL 512 L + P+VVRL D+ + +T L LVFE++D DL ++ + +P T+K + Sbjct: 68 LETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYL--DKVPEPGVPTETIKDM 125 Query: 513 MYQLCKGVAFCH 548 M+QL +G+ F H Sbjct: 126 MFQLLRGLDFLH 137
>PHO85_YEAST (P17157) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 305 Score = 96.7 bits (239), Expect = 4e-20 Identities = 55/126 (43%), Positives = 81/126 (64%), Gaps = 2/126 (1%) Frame = +3 Query: 177 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 356 +++LEK+G GTY VYK K TG VALK+ +L + +EG P TA+RE+SL++ L + + Sbjct: 7 FKQLEKLGNGTYATVYKGLNKTTGVYVALKEVKL-DSEEGTPSTAIREISLMKELKHE-N 64 Query: 357 VVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFI--RGHRQNHQKIPAHTVKILMYQLCK 530 +VRL D+ +NK L LVFE+MD DLKK++ R + + + VK +QL + Sbjct: 65 IVRLYDVIHTENK-----LTLVFEFMDNDLKKYMDSRTVGNTPRGLELNLVKYFQWQLLQ 119 Query: 531 GVAFCH 548 G+AFCH Sbjct: 120 GLAFCH 125
>PCTK1_RAT (Q63686) Serine/threonine-protein kinase PCTAIRE-1 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 1) Length = 496 Score = 96.7 bits (239), Expect = 4e-20 Identities = 57/138 (41%), Positives = 83/138 (60%) Frame = +3 Query: 135 PMXXXXXXLRAMDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTAL 314 P+ ++ Y KL+K+GEGTY VYK + K T +VALK+ RL E +EG P TA+ Sbjct: 151 PVSLSEIGFGKLETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRL-EHEEGAPCTAI 209 Query: 315 REVSLLRMLSQDPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPA 494 REVSLL+ L + ++V L D+ + L LVFEY+D DLK+++ I Sbjct: 210 REVSLLKDL-KHANIVTLHDIIHTEKS-----LTLVFEYLDKDLKQYL---DDCGNVINM 260 Query: 495 HTVKILMYQLCKGVAFCH 548 H VK+ ++QL +G+A+CH Sbjct: 261 HNVKLFLFQLLRGLAYCH 278
>PCTK1_MOUSE (Q04735) Serine/threonine-protein kinase PCTAIRE-1 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 1) (CRK5) Length = 496 Score = 96.3 bits (238), Expect = 5e-20 Identities = 56/127 (44%), Positives = 81/127 (63%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 ++ Y KL+K+GEGTY VYK + K T +VALK+ RL E +EG P TA+REVSLL+ L + Sbjct: 162 LETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRL-EHEEGAPCTAIREVSLLKDL-K 219 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 ++V L D+ + L LVFEY+D DLK+++ I H VK+ ++QL Sbjct: 220 HANIVTLHDIIHTEKS-----LTLVFEYLDKDLKQYL---DDCGNVINMHNVKLFLFQLL 271 Query: 528 KGVAFCH 548 +G+A+CH Sbjct: 272 RGLAYCH 278
>PCTK1_HUMAN (Q00536) Serine/threonine-protein kinase PCTAIRE-1 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 1) Length = 496 Score = 95.9 bits (237), Expect = 7e-20 Identities = 56/127 (44%), Positives = 81/127 (63%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 ++ Y KL+K+GEGTY VYK + K T +VALK+ RL E +EG P TA+REVSLL+ L + Sbjct: 162 LETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRL-EHEEGAPCTAIREVSLLKDL-K 219 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 ++V L D+ + L LVFEY+D DLK+++ I H VK+ ++QL Sbjct: 220 HANIVTLHDIIHTEKS-----LTLVFEYLDKDLKQYL---DDCGNIINMHNVKLFLFQLL 271 Query: 528 KGVAFCH 548 +G+A+CH Sbjct: 272 RGLAYCH 278
>CDC2H_PLACH (Q4Y4B1) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 288 Score = 95.9 bits (237), Expect = 7e-20 Identities = 55/127 (43%), Positives = 80/127 (62%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 M+ Y LEK+GEGTYG VYKA + + G ALKK RL ++DEG+P TA+RE+S+L+ L + Sbjct: 1 MEKYHGLEKIGEGTYGVVYKA-QNSDGESFALKKIRLEKEDEGIPSTAIREISILKEL-R 58 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 ++V+L D+ + + L LVFE++D DLKK I + + T K + QL Sbjct: 59 HSNIVKLYDVIHAKKR-----LILVFEHLDQDLKKLIDVCDGGLESV---TAKSFLLQLL 110 Query: 528 KGVAFCH 548 G+A+CH Sbjct: 111 NGIAYCH 117
>CDC2H_PLABA (Q4Z6R1) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 288 Score = 95.9 bits (237), Expect = 7e-20 Identities = 55/127 (43%), Positives = 80/127 (62%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 M+ Y LEK+GEGTYG VYKA + + G ALKK RL ++DEG+P TA+RE+S+L+ L + Sbjct: 1 MEKYHGLEKIGEGTYGVVYKA-QNSDGESFALKKIRLEKEDEGIPSTAIREISILKEL-R 58 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 ++V+L D+ + + L LVFE++D DLKK I + + T K + QL Sbjct: 59 HSNIVKLYDVIHAKKR-----LILVFEHLDQDLKKLIDVCDGGLESV---TAKSFLLQLL 110 Query: 528 KGVAFCH 548 G+A+CH Sbjct: 111 NGIAYCH 117
>CDC2H_PLAFK (Q07785) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (PfPK5) Length = 288 Score = 94.7 bits (234), Expect = 2e-19 Identities = 54/129 (41%), Positives = 78/129 (60%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 M+ Y LEK+GEGTYG VYKA+ G ALKK RL ++DEG+P T +RE+S+L+ L Sbjct: 1 MEKYHGLEKIGEGTYGVVYKAQNNY-GETFALKKIRLEKEDEGIPSTTIREISILKELKH 59 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 ++V+L D+ + + L LVFE++D DLKK + + + T K + QL Sbjct: 60 S-NIVKLYDVIHTKKR-----LVLVFEHLDQDLKKLLDVCEGGLESV---TAKSFLLQLL 110 Query: 528 KGVAFCHGR 554 G+A+CH R Sbjct: 111 NGIAYCHDR 119
>CDC2H_PLAF7 (P61075) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 288 Score = 94.7 bits (234), Expect = 2e-19 Identities = 54/129 (41%), Positives = 78/129 (60%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 M+ Y LEK+GEGTYG VYKA+ G ALKK RL ++DEG+P T +RE+S+L+ L Sbjct: 1 MEKYHGLEKIGEGTYGVVYKAQNNY-GETFALKKIRLEKEDEGIPSTTIREISILKELKH 59 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 ++V+L D+ + + L LVFE++D DLKK + + + T K + QL Sbjct: 60 S-NIVKLYDVIHTKKR-----LVLVFEHLDQDLKKLLDVCEGGLESV---TAKSFLLQLL 110 Query: 528 KGVAFCHGR 554 G+A+CH R Sbjct: 111 NGIAYCHDR 119
>CDC2H_PLAVI (Q9XZD6) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (Pvcrk2) Length = 288 Score = 94.0 bits (232), Expect = 3e-19 Identities = 54/127 (42%), Positives = 78/127 (61%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 M+ Y LEK+GEGTYG VYKA+ G ALKK RL ++DEG+P TA+RE+S+L+ L Sbjct: 1 MEKYHGLEKIGEGTYGVVYKAQNNY-GETFALKKIRLEKEDEGIPSTAIREISILKELKH 59 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 ++V+L D+ + + L LVFE++D DLKK + + + T K + QL Sbjct: 60 S-NIVKLYDVIHTKKR-----LILVFEHLDQDLKKLLDVCDGGLESV---TAKSFLLQLL 110 Query: 528 KGVAFCH 548 G+A+CH Sbjct: 111 SGIAYCH 117
>CDC2H_PLAKH (O96821) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 288 Score = 94.0 bits (232), Expect = 3e-19 Identities = 54/127 (42%), Positives = 78/127 (61%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 M+ Y LEK+GEGTYG VYKA+ G ALKK RL ++DEG+P TA+RE+S+L+ L Sbjct: 1 MEKYHGLEKIGEGTYGVVYKAQNNY-GETFALKKIRLEKEDEGIPSTAIREISILKELKH 59 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 ++V+L D+ + + L LVFE++D DLKK + + + T K + QL Sbjct: 60 S-NIVKLYDVIHTKKR-----LILVFEHLDQDLKKLLDVCDGGLESV---TAKSFLLQLL 110 Query: 528 KGVAFCH 548 G+A+CH Sbjct: 111 SGIAYCH 117
>CD2L5_HUMAN (Q14004) Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22)| (CDC2-related protein kinase 5) (Cholinesterase-related cell division controller) Length = 1512 Score = 94.0 bits (232), Expect = 3e-19 Identities = 53/138 (38%), Positives = 80/138 (57%), Gaps = 9/138 (6%) Frame = +3 Query: 162 RAMDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 341 R +D ++ + +GEGTYG+VYKAR+K TG +VALKK RL + EG P TA+RE+ +LR L Sbjct: 700 RCVDKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQL 759 Query: 342 SQDPHVVRLLDLKQGQN-----KEGQTILYLVFEYMDTDLKKFIRG----HRQNHQKIPA 494 + ++ + ++ + K+ + YLVFEYMD DL + +NH Sbjct: 760 THQ-SIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENH----- 813 Query: 495 HTVKILMYQLCKGVAFCH 548 +K M QL +G+ +CH Sbjct: 814 --IKSFMRQLMEGLDYCH 829
>CD2L5_MOUSE (Q69ZA1) Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22)| (CDC2-related protein kinase 5) Length = 1511 Score = 94.0 bits (232), Expect = 3e-19 Identities = 53/138 (38%), Positives = 80/138 (57%), Gaps = 9/138 (6%) Frame = +3 Query: 162 RAMDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 341 R +D ++ + +GEGTYG+VYKAR+K TG +VALKK RL + EG P TA+RE+ +LR L Sbjct: 700 RCVDKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQL 759 Query: 342 SQDPHVVRLLDLKQGQN-----KEGQTILYLVFEYMDTDLKKFIRG----HRQNHQKIPA 494 + ++ + ++ + K+ + YLVFEYMD DL + +NH Sbjct: 760 THQ-SIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENH----- 813 Query: 495 HTVKILMYQLCKGVAFCH 548 +K M QL +G+ +CH Sbjct: 814 --IKSFMRQLMEGLDYCH 829
>CDK2_ENTHI (Q04770) Cell division protein kinase 2 homolog (EC 2.7.11.22)| Length = 291 Score = 93.2 bits (230), Expect = 4e-19 Identities = 52/127 (40%), Positives = 78/127 (61%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 M YEK +++GEGTYG V KA + R VALKK + +D+G+P T++RE+++L L + Sbjct: 1 MTRYEKKQQLGEGTYGVVCKAWDTVCNRYVALKKIKQEREDDGIPVTSVREIAVLLEL-K 59 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 P+VV L D+ LYLVFE+ D DL +F+ KIP + + ++YQ+ Sbjct: 60 HPNVVDLYDIYLEDK-----FLYLVFEFCDEDLYQFM----SRSSKIPINETRSIVYQIL 110 Query: 528 KGVAFCH 548 +G+AFCH Sbjct: 111 QGLAFCH 117
>CDC2B_ANTMA (Q38773) Cell division control protein 2 homolog B (EC 2.7.11.22)| (EC 2.7.11.23) (Fragment) Length = 280 Score = 93.2 bits (230), Expect = 4e-19 Identities = 51/113 (45%), Positives = 74/113 (65%) Frame = +3 Query: 210 YGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPHVVRLLDLKQGQ 389 YG VYKAR+ T +ALKK RL ++DEGVP TA+RE+SLL+ + + ++V L D+ + Sbjct: 2 YGVVYKARDIETNEDIALKKIRLEQEDEGVPSTAIREISLLKEMHHE-NIVNLKDVVHRE 60 Query: 390 NKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLCKGVAFCH 548 + LYLVFEY+D DLKK + + Q + H VK+ + Q+ +GVA+CH Sbjct: 61 KR-----LYLVFEYLDLDLKKHMDSCPEFSQDL--HMVKMFLCQILRGVAYCH 106
>CDKL1_BRARE (Q6AXJ9) Cyclin-dependent kinase-like 1 (EC 2.7.11.22)| Length = 350 Score = 92.0 bits (227), Expect = 1e-18 Identities = 53/131 (40%), Positives = 81/131 (61%), Gaps = 4/131 (3%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 M+ YEK+ K+GEG+YG V+K R K TG+IVA+KK EDD + ALRE+ +L+ L + Sbjct: 1 MEKYEKISKIGEGSYGVVFKCRNKDTGQIVAIKKFVESEDDPIIKKIALREIRMLKQL-K 59 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMD----TDLKKFIRGHRQNHQKIPAHTVKILM 515 P++V L+++ + + K L+LVFEY D +L ++ RG +P H VK ++ Sbjct: 60 HPNLVNLMEVFRRKRK-----LHLVFEYCDHTVLNELDRYPRG-------VPEHMVKSII 107 Query: 516 YQLCKGVAFCH 548 +Q + V FCH Sbjct: 108 WQTLQAVNFCH 118
>CD2L7_HUMAN (Q9NYV4) Cell division cycle 2-related protein kinase 7 (EC| 2.7.11.22) (CDC2-related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS) Length = 1490 Score = 92.0 bits (227), Expect = 1e-18 Identities = 53/134 (39%), Positives = 78/134 (58%), Gaps = 5/134 (3%) Frame = +3 Query: 162 RAMDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 341 R +D ++ + +GEGTYG+VYKAR+K TG +VALKK RL + EG P TA+RE+ +LR L Sbjct: 722 RCVDKFDIIGIIGEGTYGQVYKARDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQL 781 Query: 342 SQDPHVVRLLDLKQGQN-----KEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVK 506 VV + ++ + K+ + YLVFEYMD DL + + + +K Sbjct: 782 IH-RSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSE---DHIK 837 Query: 507 ILMYQLCKGVAFCH 548 M QL +G+ +CH Sbjct: 838 SFMKQLMEGLEYCH 851
>CDC21_PEA (P19026) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| (EC 2.7.11.23) (p34) (Fragment) Length = 148 Score = 92.0 bits (227), Expect = 1e-18 Identities = 52/117 (44%), Positives = 74/117 (63%), Gaps = 7/117 (5%) Frame = +3 Query: 219 VYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPHVVRLLDLKQGQNKE 398 VYKAR++ T +ALKK RL ++DEGVP TA+RE+SLL+ + Q ++VRL D+ + + Sbjct: 2 VYKARDRVTNETIALKKIRLEQEDEGVPSTAIREISLLKEM-QHRNIVRLQDVVHSEKR- 59 Query: 399 GQTILYLVFEYMDTDLKK-------FIRGHRQNHQKIPAHTVKILMYQLCKGVAFCH 548 LYLVFEY+D DLKK F++ RQ VK+ +YQ+ G+A+CH Sbjct: 60 ----LYLVFEYLDLDLKKHMDSSPEFVKDPRQ---------VKMFLYQMLCGIAYCH 103
>CDC2H_PLAYO (Q7RM49) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 289 Score = 90.1 bits (222), Expect = 4e-18 Identities = 54/128 (42%), Positives = 80/128 (62%), Gaps = 1/128 (0%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPT-ALREVSLLRMLS 344 M+ Y LEK+GEGTYG VYKA + + G ALKK RL ++DEG+P T ++RE+S+L+ L Sbjct: 1 MEKYHGLEKIGEGTYGVVYKA-QNSDGESFALKKIRLEKEDEGIPSTVSIREISILKEL- 58 Query: 345 QDPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQL 524 + ++V+L D+ + + L LVFE++D DLKK I + + T K + QL Sbjct: 59 RHSNIVKLYDVIHAKKR-----LILVFEHLDQDLKKLIDVCDGGLESV---TAKSFLLQL 110 Query: 525 CKGVAFCH 548 G+A+CH Sbjct: 111 LNGIAYCH 118
>KC47_ORYSA (P29620) CDC2+/CDC28-related protein kinase R2 (EC 2.7.11.22)| Length = 424 Score = 90.1 bits (222), Expect = 4e-18 Identities = 58/129 (44%), Positives = 79/129 (61%) Frame = +3 Query: 162 RAMDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 341 R D Y K E +GEGTYG V+KA + TG VA+KK RL + EGV TALRE+ LL+ L Sbjct: 14 RVADRYLKREVLGEGTYGVVFKAVDTKTGNTVAIKKIRLGKYKEGVNFTALREIKLLKEL 73 Query: 342 SQDPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQ 521 +D +++ L+D + L+LVFE+M+TDL+ IR +N PA T K + Sbjct: 74 -KDSNIIELIDAFPYKGN-----LHLVFEFMETDLEAVIRD--RNIVLSPADT-KSYIQM 124 Query: 522 LCKGVAFCH 548 + KG+AFCH Sbjct: 125 MLKGLAFCH 133
>CDK4_XENLA (Q91727) Cell division protein kinase 4 (EC 2.7.11.22)| (Cyclin-dependent kinase 4) Length = 319 Score = 89.7 bits (221), Expect = 5e-18 Identities = 47/126 (37%), Positives = 77/126 (61%), Gaps = 2/126 (1%) Frame = +3 Query: 177 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLS--QD 350 YE + ++G G YG VYKAR+ +G+ VALK R+ ++ G+P + +REV+LL+ L Sbjct: 9 YEPVAEIGVGAYGTVYKARDLQSGKFVALKNVRVQTNENGLPLSTVREVTLLKRLEHFDH 68 Query: 351 PHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLCK 530 P++V+L+D+ + +T + LVFE++D DLK ++ + +P T+K LM Q Sbjct: 69 PNIVKLMDVCASARTDRETKVTLVFEHVDQDLKTYL--SKVPPPGLPLETIKDLMKQFLS 126 Query: 531 GVAFCH 548 G+ F H Sbjct: 127 GLEFLH 132
>CDKL1_HUMAN (Q00532) Cyclin-dependent kinase-like 1 (EC 2.7.11.22)| (Serine/threonine-protein kinase KKIALRE) (Protein kinase p42 KKIALRE) Length = 357 Score = 89.0 bits (219), Expect = 8e-18 Identities = 52/131 (39%), Positives = 80/131 (61%), Gaps = 4/131 (3%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 M+ YEK+ K+GEG+YG V+K R + TG+IVA+KK EDD + ALRE+ +L+ L + Sbjct: 1 MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQL-K 59 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMD----TDLKKFIRGHRQNHQKIPAHTVKILM 515 P++V LL++ + + + L+LVFEY D +L ++ RG +P H VK + Sbjct: 60 HPNLVNLLEVFRRKRR-----LHLVFEYCDHTVLHELDRYQRG-------VPEHLVKSIT 107 Query: 516 YQLCKGVAFCH 548 +Q + V FCH Sbjct: 108 WQTLQAVNFCH 118
>PFTK1_MOUSE (O35495) Serine/threonine-protein kinase PFTAIRE-1 (EC 2.7.11.22)| Length = 469 Score = 89.0 bits (219), Expect = 8e-18 Identities = 53/128 (41%), Positives = 80/128 (62%) Frame = +3 Query: 171 DLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQD 350 D YEKLEK+GEG+Y VYK + K G++VALK RL +++EG P TA+RE SLL+ L + Sbjct: 133 DSYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRL-QEEEGTPFTAIREASLLKGL-KH 190 Query: 351 PHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLCK 530 ++V L D+ + L LVFEY+ TDL +++ H + VK+ ++QL + Sbjct: 191 ANIVLLHDIIHTKE-----TLTLVFEYVHTDLCQYMEQHPGG---LHPDNVKLFLFQLLR 242 Query: 531 GVAFCHGR 554 G+++ H R Sbjct: 243 GLSYIHQR 250
>PFTK1_HUMAN (O94921) Serine/threonine-protein kinase PFTAIRE-1 (EC 2.7.11.22)| Length = 469 Score = 88.2 bits (217), Expect = 1e-17 Identities = 53/128 (41%), Positives = 80/128 (62%) Frame = +3 Query: 171 DLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQD 350 D YEKLEK+GEG+Y VYK + K G++VALK RL +++EG P TA+RE SLL+ L + Sbjct: 133 DSYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRL-QEEEGTPFTAIREASLLKGL-KH 190 Query: 351 PHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLCK 530 ++V L D+ + L LVFEY+ TDL +++ H + VK+ ++QL + Sbjct: 191 ANIVLLHDIIHTKE-----TLTLVFEYVHTDLCQYMDKHPGG---LHPDNVKLFLFQLLR 242 Query: 531 GVAFCHGR 554 G+++ H R Sbjct: 243 GLSYIHQR 250
>BUR1_YARLI (Q6C842) Serine/threonine-protein kinase BUR1 (EC 2.7.11.22) (EC| 2.7.11.23) Length = 706 Score = 88.2 bits (217), Expect = 1e-17 Identities = 52/129 (40%), Positives = 81/129 (62%), Gaps = 3/129 (2%) Frame = +3 Query: 177 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 356 Y+ L K+GEGT+G+V++A + T R VALKK L + EG P TALRE+ +L++L + + Sbjct: 38 YKPLGKIGEGTFGEVFRAEQITTKRHVALKKILLHSEKEGFPVTALREIRILKLLRHE-N 96 Query: 357 VVRLLDL---KQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 V+ L+DL + Q+K+ + +Y+V YMD DL + Q+ Q PAH +K M QL Sbjct: 97 VIPLVDLAVERGDQSKKERGCVYMVTPYMDHDLAGLL--GNQSVQLSPAH-IKCYMLQLL 153 Query: 528 KGVAFCHGR 554 +G+ + H + Sbjct: 154 EGIGYLHAK 162
>CDK4_PIG (P79432) Cell division protein kinase 4 (EC 2.7.11.22)| (Cyclin-dependent kinase 4) Length = 303 Score = 87.4 bits (215), Expect = 2e-17 Identities = 51/133 (38%), Positives = 78/133 (58%), Gaps = 5/133 (3%) Frame = +3 Query: 165 AMDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPED---DEGVPPTALREVSLLR 335 A YE + ++G G YG VYKAR+ +G VALK R+P G+P + +REV+LLR Sbjct: 2 ATSRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGAGGGLPISTVREVALLR 61 Query: 336 MLS--QDPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKI 509 L + P+VVRL+D+ + +T + LVFE++D DL+ ++ + +P T+K Sbjct: 62 RLEAFEHPNVVRLMDVCATARTDRETKVTLVFEHVDQDLRTYL--DKAPPPGLPVETIKD 119 Query: 510 LMYQLCKGVAFCH 548 LM Q +G+ F H Sbjct: 120 LMRQFLRGLDFLH 132
>CDK4_HUMAN (P11802) Cell division protein kinase 4 (EC 2.7.11.22)| (Cyclin-dependent kinase 4) (PSK-J3) Length = 303 Score = 87.0 bits (214), Expect = 3e-17 Identities = 51/133 (38%), Positives = 78/133 (58%), Gaps = 5/133 (3%) Frame = +3 Query: 165 AMDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPE---DDEGVPPTALREVSLLR 335 A YE + ++G G YG VYKAR+ +G VALK R+P G+P + +REV+LLR Sbjct: 2 ATSRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGGGGGLPISTVREVALLR 61 Query: 336 MLS--QDPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKI 509 L + P+VVRL+D+ + + + LVFE++D DL+ ++ + +PA T+K Sbjct: 62 RLEAFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYL--DKAPPPGLPAETIKD 119 Query: 510 LMYQLCKGVAFCH 548 LM Q +G+ F H Sbjct: 120 LMRQFLRGLDFLH 132
>CD2L7_CAEEL (P46551) Putative cell division cycle 2-related protein kinase 7| (EC 2.7.11.22) Length = 730 Score = 85.9 bits (211), Expect = 7e-17 Identities = 53/134 (39%), Positives = 78/134 (58%), Gaps = 7/134 (5%) Frame = +3 Query: 177 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 356 Y L+++GEGTYG+VYKA TG VALK+ RL + EG P TA+RE+ +LR L + Sbjct: 311 YTMLDQIGEGTYGQVYKAVNNLTGEQVALKRVRLENEKEGFPITAIREIKILRQL-HHKN 369 Query: 357 VVRLL-----DLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKI--LM 515 +VRL+ D+ + K + YLVFEY+D DL G ++ + + + +I L Sbjct: 370 IVRLMDIVIDDISMDELKRTRANFYLVFEYVDHDL----IGLLESKELVDFNKDQICSLF 425 Query: 516 YQLCKGVAFCHGRG 557 QL +G+A+ H G Sbjct: 426 KQLLEGLAYIHNTG 439
>BUR1_EMENI (Q96VK3) Serine/threonine-protein kinase bur1 (EC 2.7.11.22) (EC| 2.7.11.23) (Pitalre-like kinase A) Length = 544 Score = 85.1 bits (209), Expect = 1e-16 Identities = 51/128 (39%), Positives = 79/128 (61%), Gaps = 3/128 (2%) Frame = +3 Query: 177 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 356 +E L K+GEGT+G+VYKAR K G IVALKK + + +G P TALRE+ LL+MLS + Sbjct: 25 FEFLGKLGEGTFGEVYKARAKRDGSIVALKKILMHNERDGFPITALREIKLLKMLSH-TN 83 Query: 357 VVRLLDLKQGQNK-EG--QTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 +++L ++ ++K EG + +Y+VF YM+ DL + + + +K M QL Sbjct: 84 IMQLREMAVERSKGEGRKKPSMYMVFPYMEHDLSGLLENPEVHFSEA---QIKCYMIQLL 140 Query: 528 KGVAFCHG 551 +G+ + HG Sbjct: 141 EGLKYLHG 148
>CDKL5_HUMAN (O76039) Cyclin-dependent kinase-like 5 (EC 2.7.11.22)| (Serine/threonine-protein kinase 9) Length = 1030 Score = 84.3 bits (207), Expect = 2e-16 Identities = 49/127 (38%), Positives = 75/127 (59%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 M+ +E L VGEG YG V K R K T IVA+KK + E++E V T LRE+ +LR L Q Sbjct: 10 MNKFEILGVVGEGAYGVVLKCRHKETHEIVAIKKFKDSEENEEVKETTLRELKMLRTLKQ 69 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 + +++LK+ + G+ LYLVFEY++ ++ + + + +P VK +YQL Sbjct: 70 E----NIVELKEAFRRRGK--LYLVFEYVEKNMLELL---EEMPNGVPPEKVKSYIYQLI 120 Query: 528 KGVAFCH 548 K + +CH Sbjct: 121 KAIHWCH 127
>CDK9_CHICK (Q5ZKN1) Cell division protein kinase 9 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9) Length = 372 Score = 84.3 bits (207), Expect = 2e-16 Identities = 46/127 (36%), Positives = 75/127 (59%), Gaps = 3/127 (2%) Frame = +3 Query: 177 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 356 YEKL K+G+GT+G+V+KA+ + TG+ VALKK + + EG P TALRE+ +L++L + + Sbjct: 19 YEKLAKIGQGTFGEVFKAKHRQTGKKVALKKVLMENEKEGFPITALREIKILQLLKHE-N 77 Query: 357 VVRLLDL---KQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 VV L+++ K + +YLVF++ + DL + H K +K +M L Sbjct: 78 VVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLL---SNTHVKFTLSEIKKVMQMLL 134 Query: 528 KGVAFCH 548 G+ + H Sbjct: 135 NGLYYIH 141
>CDK4_RAT (P35426) Cell division protein kinase 4 (EC 2.7.11.22)| (Cyclin-dependent kinase 4) (PSK-J3) Length = 303 Score = 84.3 bits (207), Expect = 2e-16 Identities = 49/129 (37%), Positives = 74/129 (57%), Gaps = 5/129 (3%) Frame = +3 Query: 177 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDE---GVPPTALREVSLLRMLS- 344 YE + ++G G YG VYKAR+ +G VALK R+P G+P + +REV+LLR L Sbjct: 6 YEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGAAGGGLPVSTVREVALLRRLEA 65 Query: 345 -QDPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQ 521 + P+VVRL+D+ + + LVFE++D DL+ ++ + +P T+K LM Q Sbjct: 66 FEHPNVVRLMDVCATSRTDRDIKVTLVFEHIDQDLRTYL--DKAPPPGLPVETIKDLMRQ 123 Query: 522 LCKGVAFCH 548 G+ F H Sbjct: 124 FLSGLDFLH 132
>CDK4_MOUSE (P30285) Cell division protein kinase 4 (EC 2.7.11.22)| (Cyclin-dependent kinase 4) (PSK-J3) (CRK3) Length = 303 Score = 84.3 bits (207), Expect = 2e-16 Identities = 49/129 (37%), Positives = 74/129 (57%), Gaps = 5/129 (3%) Frame = +3 Query: 177 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDE---GVPPTALREVSLLRMLS- 344 YE + ++G G YG VYKAR+ +G VALK R+P G+P + +REV+LLR L Sbjct: 6 YEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGAAGGGLPVSTVREVALLRRLEA 65 Query: 345 -QDPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQ 521 + P+VVRL+D+ + + LVFE++D DL+ ++ + +P T+K LM Q Sbjct: 66 FEHPNVVRLMDVCATSRTDRDIKVTLVFEHIDQDLRTYL--DKAPPPGLPVETIKDLMRQ 123 Query: 522 LCKGVAFCH 548 G+ F H Sbjct: 124 FLSGLDFLH 132
>YP62_CAEEL (Q09437) Putative serine/threonine-protein kinase B0495.2 (EC| 2.7.11.1) Length = 719 Score = 84.3 bits (207), Expect = 2e-16 Identities = 41/129 (31%), Positives = 75/129 (58%) Frame = +3 Query: 162 RAMDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 341 R +D YE + +V EGT+G VY+ ++K T IVALK+ ++ ++ EG P TALRE+++L Sbjct: 351 RNIDEYECVNRVDEGTFGVVYRGKDKRTDEIVALKRLKMEKEKEGFPITALREINMLLKA 410 Query: 342 SQDPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQ 521 P++V + ++ G N + +Y+ E+++ D+K + + +++ K L+ Q Sbjct: 411 GNHPNIVNVKEILLGSNMDK---IYMAMEFVEHDMKSLLDTMSRRNKRFSIGEQKTLLQQ 467 Query: 522 LCKGVAFCH 548 L G+ H Sbjct: 468 LLSGIEHMH 476
>KP58_DROME (Q9VPC0) Serine/threonine-protein kinase PITSLRE (EC 2.7.11.22)| (Cell division cycle 2-like) Length = 952 Score = 84.3 bits (207), Expect = 2e-16 Identities = 44/129 (34%), Positives = 78/129 (60%) Frame = +3 Query: 162 RAMDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 341 R+++ ++ L ++ EGTYG VY+A++K T IVALK+ ++ ++ EG P T+LRE++ L + Sbjct: 553 RSVEEFQCLNRIEEGTYGVVYRAKDKRTNEIVALKRLKMEKEKEGFPITSLREINTL-LK 611 Query: 342 SQDPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQ 521 Q P++V + ++ G N + +++V +Y++ DLK + + Q VK L Q Sbjct: 612 GQHPNIVTVREIVVGSNMDK---IFIVMDYVEHDLKSLMETMKNRKQSFFPGEVKCLTQQ 668 Query: 522 LCKGVAFCH 548 L + VA H Sbjct: 669 LLRAVAHLH 677
>CDKL4_MOUSE (Q3TZA2) Cyclin-dependent kinase-like 4 (EC 2.7.11.22)| Length = 342 Score = 84.0 bits (206), Expect = 3e-16 Identities = 47/127 (37%), Positives = 78/127 (61%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 M+ YEKL K+GEG+YG V+K R K++G++VA+KK EDD V ALRE+ +L+ L + Sbjct: 1 MEKYEKLAKIGEGSYGVVFKCRNKSSGQVVAIKKFVESEDDRVVRKIALREIRMLKQL-K 59 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 P++V L+++ + + K ++LVFEY D L + +N + +K +++Q Sbjct: 60 HPNLVNLIEVFRRKRK-----MHLVFEYCDHTL---LNELERNPNGVSDGVIKSVLWQTL 111 Query: 528 KGVAFCH 548 + + FCH Sbjct: 112 QALNFCH 118
>CDKL1_MOUSE (Q8CEQ0) Cyclin-dependent kinase-like 1 (EC 2.7.11.22)| Length = 352 Score = 83.6 bits (205), Expect = 3e-16 Identities = 50/131 (38%), Positives = 79/131 (60%), Gaps = 4/131 (3%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 M+ YEK+ K+GEG+YG V+K R + TG+IVA+K+ EDD + ALRE+ +L+ L + Sbjct: 1 MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKRFLETEDDPVIKKIALREIRMLKQL-K 59 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMD----TDLKKFIRGHRQNHQKIPAHTVKILM 515 P++V LL++ + + + L+LVFEY D +L ++ RG +P VK + Sbjct: 60 HPNLVNLLEVFRRKRR-----LHLVFEYCDHTVLHELDRYQRG-------VPEPLVKNIT 107 Query: 516 YQLCKGVAFCH 548 +Q + V FCH Sbjct: 108 WQTLQAVNFCH 118
>CD2L1_HUMAN (P21127) PITSLRE serine/threonine-protein kinase CDC2L1 (EC| 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1) Length = 795 Score = 83.2 bits (204), Expect = 5e-16 Identities = 46/129 (35%), Positives = 81/129 (62%) Frame = +3 Query: 162 RAMDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 341 R+++ ++ L ++ EGTYG VY+A++K T IVALK+ ++ ++ EG P T+LRE++ + + Sbjct: 433 RSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTI-LK 491 Query: 342 SQDPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQ 521 +Q P++V + ++ G N + +Y+V Y++ DLK + +Q +P VK LM Q Sbjct: 492 AQHPNIVTVREIVVGSNMDK---IYIVMNYVEHDLKSLMETMKQPF--LPGE-VKTLMIQ 545 Query: 522 LCKGVAFCH 548 L +GV H Sbjct: 546 LLRGVKHLH 554
>CD2L2_HUMAN (Q9UQ88) PITSLRE serine/threonine-protein kinase CDC2L2 (EC| 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 2) (CDK11) Length = 780 Score = 83.2 bits (204), Expect = 5e-16 Identities = 46/129 (35%), Positives = 81/129 (62%) Frame = +3 Query: 162 RAMDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 341 R+++ ++ L ++ EGTYG VY+A++K T IVALK+ ++ ++ EG P T+LRE++ + + Sbjct: 418 RSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTI-LK 476 Query: 342 SQDPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQ 521 +Q P++V + ++ G N + +Y+V Y++ DLK + +Q +P VK LM Q Sbjct: 477 AQHPNIVTVREIVVGSNMDK---IYIVMNYVEHDLKSLMETMKQPF--LPGE-VKTLMIQ 530 Query: 522 LCKGVAFCH 548 L +GV H Sbjct: 531 LLRGVKHLH 539
>BUR1_ASPFU (Q4WTN5) Serine/threonine-protein kinase bur1 (EC 2.7.11.22) (EC| 2.7.11.23) Length = 580 Score = 82.4 bits (202), Expect = 8e-16 Identities = 49/128 (38%), Positives = 76/128 (59%), Gaps = 3/128 (2%) Frame = +3 Query: 177 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 356 +E L K+GEGT+G+VYKAR K G IVALKK + + +G P TALRE+ LL+MLS + Sbjct: 25 FEFLGKLGEGTFGEVYKARSKKDGSIVALKKILMHNEKDGFPITALREIKLLKMLSH-RN 83 Query: 357 VVRLLDLKQGQNK---EGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 +++L ++ ++K + +Y+V YM+ DL + N + +K M QL Sbjct: 84 ILQLKEMAVERSKGDGRKKPSMYMVTPYMEHDLSGLLENPAVNFTE---PQIKCYMLQLL 140 Query: 528 KGVAFCHG 551 +G+ + HG Sbjct: 141 EGLKYLHG 148
>CD2L1_MOUSE (P24788) PITSLRE serine/threonine-protein kinase CDC2L1 (EC| 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) Length = 784 Score = 82.4 bits (202), Expect = 8e-16 Identities = 46/129 (35%), Positives = 80/129 (62%) Frame = +3 Query: 162 RAMDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 341 R+++ ++ L ++ EGTYG VY+A++K T IVALK+ ++ ++ EG P T+LRE++ + + Sbjct: 422 RSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTI-LK 480 Query: 342 SQDPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQ 521 +Q P++V + ++ G N + +Y+V Y++ DLK + +Q +P VK LM Q Sbjct: 481 AQHPNIVTVREIVVGSNMDK---IYIVMNYVEHDLKSLMETMKQPF--LPGE-VKTLMIQ 534 Query: 522 LCKGVAFCH 548 L GV H Sbjct: 535 LLSGVKHLH 543
>CDKL4_HUMAN (Q5MAI5) Cyclin-dependent kinase-like 4 (EC 2.7.11.22)| Length = 315 Score = 82.0 bits (201), Expect = 1e-15 Identities = 47/127 (37%), Positives = 76/127 (59%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 M+ YEKL K GEG+YG V+K R K +G++VA+KK EDD V ALRE+ +L+ L + Sbjct: 1 MEKYEKLAKTGEGSYGVVFKCRNKTSGQVVAVKKFVESEDDPVVKKIALREIRMLKQL-K 59 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 P++V L+++ + + K ++LVFEY D L + +N + +K +++Q Sbjct: 60 HPNLVNLIEVFRRKRK-----MHLVFEYCDHTL---LNELERNPNGVADGVIKSVLWQTL 111 Query: 528 KGVAFCH 548 + + FCH Sbjct: 112 QALNFCH 118
>CD2L1_RAT (P46892) PITSLRE serine/threonine-protein kinase CDC2L1 (EC| 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) Length = 436 Score = 81.6 bits (200), Expect = 1e-15 Identities = 45/129 (34%), Positives = 80/129 (62%) Frame = +3 Query: 162 RAMDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 341 R+++ ++ L ++ EGTYG VY+A++K T IVALK+ ++ ++ EG P T++RE++ + + Sbjct: 74 RSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPLTSIREINTI-LK 132 Query: 342 SQDPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQ 521 +Q P++V + ++ G N + +Y+V Y++ DLK + +Q +P VK LM Q Sbjct: 133 AQHPNIVTVREIVVGSNMDK---IYIVMNYVEHDLKSLMETMKQPF--LPGE-VKTLMIQ 186 Query: 522 LCKGVAFCH 548 L GV H Sbjct: 187 LLSGVKHLH 195
>CDK10_HUMAN (Q15131) Cell division protein kinase 10 (EC 2.7.11.22)| (Serine/threonine-protein kinase PISSLRE) Length = 360 Score = 81.6 bits (200), Expect = 1e-15 Identities = 45/129 (34%), Positives = 78/129 (60%) Frame = +3 Query: 162 RAMDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 341 R++ +EKL ++GEGTYG VY+AR+ T IVALKK R+ ++ +G+P ++LRE++LL L Sbjct: 34 RSVKEFEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLRL 93 Query: 342 SQDPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQ 521 + P++V L ++ G + E ++LV Y + DL + + VK ++ Q Sbjct: 94 -RHPNIVELKEVVVGNHLES---IFLVMGYCEQDLASLLENMPTPFSEA---QVKCIVLQ 146 Query: 522 LCKGVAFCH 548 + +G+ + H Sbjct: 147 VLRGLQYLH 155
>CTK1_YEAST (Q03957) CTD kinase subunit alpha (EC 2.7.11.23) (CTD kinase 58 kDa| subunit) (CTDK-I alpha subunit) Length = 528 Score = 80.5 bits (197), Expect = 3e-15 Identities = 48/129 (37%), Positives = 72/129 (55%) Frame = +3 Query: 162 RAMDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 341 R+ +Y ++ +VGEGTYGKVYKA+ T ++VALKK RL + EG P T++RE+ LL+ Sbjct: 178 RSTSVYLRIMQVGEGTYGKVYKAKNTNTEKLVALKKLRLQGEREGFPITSIREIKLLQSF 237 Query: 342 SQDPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQ 521 P+V + ++ E Q +Y++FEY D DL + +I K L Q Sbjct: 238 DH-PNVSTIKEIM----VESQKTVYMIFEYADNDLSGLL---LNKEVQISHSQCKHLFKQ 289 Query: 522 LCKGVAFCH 548 L G+ + H Sbjct: 290 LLLGMEYLH 298
>CDKL1_RAT (Q66HE7) Cyclin-dependent kinase-like 1 (EC 2.7.11.22)| Length = 352 Score = 80.5 bits (197), Expect = 3e-15 Identities = 49/131 (37%), Positives = 78/131 (59%), Gaps = 4/131 (3%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 M+ YEK+ K+GEG+YG V+K R + TG+IVA+K+ EDD + ALRE+ +L+ L + Sbjct: 1 MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKRFLETEDDPVIKKIALREIRMLKQL-K 59 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMD----TDLKKFIRGHRQNHQKIPAHTVKILM 515 P++V LL++ + + + L+LVFEY +L ++ RG +P VK + Sbjct: 60 HPNLVSLLEVFRRKRR-----LHLVFEYCHHTVLHELDRYQRG-------VPEPLVKNIT 107 Query: 516 YQLCKGVAFCH 548 +Q + V FCH Sbjct: 108 WQTLQAVNFCH 118
>CDK9_HUMAN (P50750) Cell division protein kinase 9 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9) (Serine/threonine-protein kinase PITALRE) (C-2K) (Cell division cycle 2-like protein kinase 4) Length = 372 Score = 80.1 bits (196), Expect = 4e-15 Identities = 46/127 (36%), Positives = 74/127 (58%), Gaps = 3/127 (2%) Frame = +3 Query: 177 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 356 YEKL K+G+GT+G+V+KAR + TG+ VALKK + + EG P TALRE+ +L++L + + Sbjct: 19 YEKLAKIGQGTFGEVFKARHRKTGQKVALKKVLMENEKEGFPITALREIKILQLLKHE-N 77 Query: 357 VVRLLDL---KQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 VV L+++ K + +YLVF++ + DL + K +K +M L Sbjct: 78 VVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNVL---VKFTLSEIKRVMQMLL 134 Query: 528 KGVAFCH 548 G+ + H Sbjct: 135 NGLYYIH 141
>CDC2H_CRIFA (Q01917) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 474 Score = 80.1 bits (196), Expect = 4e-15 Identities = 47/127 (37%), Positives = 76/127 (59%), Gaps = 1/127 (0%) Frame = +3 Query: 177 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 356 Y + K+GEGTYG VYK E TGR+VA K+ + DDEG+P A+RE+ LL+ L + + Sbjct: 7 YRHVVKLGEGTYGMVYKGTEIQTGRVVAFKRMVVTSDDEGIPGAAIREICLLKELRHN-N 65 Query: 357 VVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHT-VKILMYQLCKG 533 VV L ++ K + ++FE D DLK+++ Q + + A+T ++ ++ Q+ G Sbjct: 66 VVELFEVLFDPPK-----ITMIFELCDCDLKRYMESRPQ--RLLDANTEMRPILKQIFLG 118 Query: 534 VAFCHGR 554 + + HGR Sbjct: 119 LEYLHGR 125
>CDKL2_RAT (Q5XIT0) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| Length = 507 Score = 79.7 bits (195), Expect = 5e-15 Identities = 50/131 (38%), Positives = 75/131 (57%), Gaps = 4/131 (3%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 M+ YE L VGEG+YG V K R K +GRIVA+KK +DD+ V A+RE+ LL+ L Sbjct: 1 MEKYENLGLVGEGSYGMVMKCRNKDSGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRH 60 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMD----TDLKKFIRGHRQNHQKIPAHTVKILM 515 + ++V LL++ + + + YLVFE++D DLK F G + V+ + Sbjct: 61 E-NLVNLLEVCKKKKR-----WYLVFEFVDHTILDDLKLFPNG-------LDYQVVQKYL 107 Query: 516 YQLCKGVAFCH 548 +Q+ G+ FCH Sbjct: 108 FQIINGIGFCH 118
>CDK9_XENTR (Q6GLD8) Cell division protein kinase 9 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9) Length = 376 Score = 79.7 bits (195), Expect = 5e-15 Identities = 44/131 (33%), Positives = 75/131 (57%), Gaps = 7/131 (5%) Frame = +3 Query: 177 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 356 YE+L K+G+GT+G+V+KA+ + TG+ VALKK + + EG P TALRE+ +L++L + + Sbjct: 19 YERLAKIGQGTFGEVFKAKHRQTGKKVALKKVLMENEKEGFPITALREIKILQLLKHE-N 77 Query: 357 VVRLLDL-------KQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILM 515 VV L+++ Q + ++LVF++ + DL + H K +K +M Sbjct: 78 VVNLIEICRTKISPTANQYNRCKGTIFLVFDFCEHDLAGLL---SNAHVKFTLSEIKKVM 134 Query: 516 YQLCKGVAFCH 548 L G+ + H Sbjct: 135 QMLLNGLYYIH 145
>CDK9B_XENLA (Q7ZX42) Cell division protein kinase 9-B (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9-B) Length = 376 Score = 79.7 bits (195), Expect = 5e-15 Identities = 44/131 (33%), Positives = 75/131 (57%), Gaps = 7/131 (5%) Frame = +3 Query: 177 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 356 YE+L K+G+GT+G+V+KA+ + TG+ VALKK + + EG P TALRE+ +L++L + + Sbjct: 19 YERLAKIGQGTFGEVFKAKHRQTGKKVALKKVLMENEKEGFPITALREIKILQLLKHE-N 77 Query: 357 VVRLLDL-------KQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILM 515 VV L+++ Q + ++LVF++ + DL + H K +K +M Sbjct: 78 VVHLIEICRNKISPTANQYNRCKGTIFLVFDFCEHDLAGLL---SNAHVKFTVAEIKKVM 134 Query: 516 YQLCKGVAFCH 548 L G+ + H Sbjct: 135 QMLLNGLYYIH 145
>CDK9A_XENLA (Q4V862) Cell division protein kinase 9-A (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9-A) Length = 376 Score = 79.7 bits (195), Expect = 5e-15 Identities = 44/131 (33%), Positives = 75/131 (57%), Gaps = 7/131 (5%) Frame = +3 Query: 177 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 356 YE+L K+G+GT+G+V+KA+ + TG+ VALKK + + EG P TALRE+ +L++L + + Sbjct: 19 YERLAKIGQGTFGEVFKAKHRQTGKKVALKKVLMENEKEGFPITALREIKILQLLKHE-N 77 Query: 357 VVRLLDL-------KQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILM 515 VV L+++ Q + ++LVF++ + DL + H K +K +M Sbjct: 78 VVNLIEICRTKVSPTANQYNRCKGTIFLVFDFCEHDLAGLL---SNAHVKFTLSEIKKVM 134 Query: 516 YQLCKGVAFCH 548 L G+ + H Sbjct: 135 QMLLNGLYYIH 145
>CDKL2_MACFA (Q4R7T5) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| Length = 570 Score = 79.7 bits (195), Expect = 5e-15 Identities = 50/131 (38%), Positives = 75/131 (57%), Gaps = 4/131 (3%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 M+ YE L VGEG+YG V K R K TGRIVA+KK +DD+ V A+RE+ LL+ L Sbjct: 1 MEKYENLGLVGEGSYGMVVKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRH 60 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMD----TDLKKFIRGHRQNHQKIPAHTVKILM 515 + ++V LL++ + + + YLVFE++D DL+ F G + V+ + Sbjct: 61 E-NLVNLLEVCKKKKR-----WYLVFEFVDHTILDDLELFPNG-------LDYQVVQKYL 107 Query: 516 YQLCKGVAFCH 548 +Q+ G+ FCH Sbjct: 108 FQIINGIGFCH 118
>CDKL2_PONPY (Q5R754) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| Length = 493 Score = 79.7 bits (195), Expect = 5e-15 Identities = 50/131 (38%), Positives = 75/131 (57%), Gaps = 4/131 (3%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 M+ YE L VGEG+YG V K R K TGRIVA+KK +DD+ V A+RE+ LL+ L Sbjct: 1 MEKYENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRH 60 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMD----TDLKKFIRGHRQNHQKIPAHTVKILM 515 + ++V LL++ + + + YLVFE++D DL+ F G + V+ + Sbjct: 61 E-NLVNLLEVCKKKKR-----WYLVFEFVDHTILDDLELFPNG-------LDYQVVQKYL 107 Query: 516 YQLCKGVAFCH 548 +Q+ G+ FCH Sbjct: 108 FQIINGIGFCH 118
>CDKL2_HUMAN (Q92772) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| (Serine/threonine-protein kinase KKIAMRE) (Protein kinase p56 KKIAMRE) Length = 493 Score = 79.7 bits (195), Expect = 5e-15 Identities = 50/131 (38%), Positives = 75/131 (57%), Gaps = 4/131 (3%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 M+ YE L VGEG+YG V K R K TGRIVA+KK +DD+ V A+RE+ LL+ L Sbjct: 1 MEKYENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRH 60 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMD----TDLKKFIRGHRQNHQKIPAHTVKILM 515 + ++V LL++ + + + YLVFE++D DL+ F G + V+ + Sbjct: 61 E-NLVNLLEVCKKKKR-----WYLVFEFVDHTILDDLELFPNG-------LDYQVVQKYL 107 Query: 516 YQLCKGVAFCH 548 +Q+ G+ FCH Sbjct: 108 FQIINGIGFCH 118
>CDKL2_MOUSE (Q9QUK0) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| (Serine/threonine-protein kinase KKIAMRE) Length = 568 Score = 79.7 bits (195), Expect = 5e-15 Identities = 50/131 (38%), Positives = 75/131 (57%), Gaps = 4/131 (3%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 M+ YE L VGEG+YG V K R K +GRIVA+KK +DD+ V A+RE+ LL+ L Sbjct: 1 MEKYENLGLVGEGSYGMVMKCRNKDSGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRH 60 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMD----TDLKKFIRGHRQNHQKIPAHTVKILM 515 + ++V LL++ + + + YLVFE++D DLK F G + V+ + Sbjct: 61 E-NLVNLLEVCKKKKR-----WYLVFEFVDHTILDDLKLFPNG-------LDYQVVQKYL 107 Query: 516 YQLCKGVAFCH 548 +Q+ G+ FCH Sbjct: 108 FQIINGIGFCH 118
>BUR1_GIBZE (Q4I5U9) Serine/threonine-protein kinase BUR1 (EC 2.7.11.22) (EC| 2.7.11.23) Length = 473 Score = 79.0 bits (193), Expect = 9e-15 Identities = 47/129 (36%), Positives = 76/129 (58%), Gaps = 5/129 (3%) Frame = +3 Query: 177 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 356 YE L K+GEGT+G+V++AR + TG +VALKK + + +G P TALRE+ LL++LS + Sbjct: 37 YELLGKLGEGTFGEVHRARLRKTGALVALKKIIMHHEKDGFPITALREIKLLKLLSH-KN 95 Query: 357 VVRLLDL-----KQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQ 521 ++RL D+ + +K + I+Y+ YMD DL + ++ +K M Q Sbjct: 96 ILRLEDMAIEHPTRQTDKRKKPIVYMATPYMDHDLSGLLDNPSVQFKE---PQIKCYMLQ 152 Query: 522 LCKGVAFCH 548 L +G+ + H Sbjct: 153 LLEGLRYLH 161
>CDK9_RAT (Q641Z4) Cell division protein kinase 9 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9) Length = 372 Score = 79.0 bits (193), Expect = 9e-15 Identities = 45/127 (35%), Positives = 74/127 (58%), Gaps = 3/127 (2%) Frame = +3 Query: 177 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 356 YEKL K+G+GT+G+V+KA+ + TG+ VALKK + + EG P TALRE+ +L++L + + Sbjct: 19 YEKLAKIGQGTFGEVFKAKHRQTGQKVALKKVLMENEKEGFPITALREIKILQLLKHE-N 77 Query: 357 VVRLLDL---KQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 VV L+++ K + +YLVF++ + DL + K +K +M L Sbjct: 78 VVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNVL---VKFTLSEIKRVMQMLL 134 Query: 528 KGVAFCH 548 G+ + H Sbjct: 135 NGLYYIH 141
>CDK9_MOUSE (Q99J95) Cell division protein kinase 9 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9) Length = 372 Score = 79.0 bits (193), Expect = 9e-15 Identities = 45/127 (35%), Positives = 74/127 (58%), Gaps = 3/127 (2%) Frame = +3 Query: 177 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 356 YEKL K+G+GT+G+V+KA+ + TG+ VALKK + + EG P TALRE+ +L++L + + Sbjct: 19 YEKLAKIGQGTFGEVFKAKHRQTGQKVALKKVLMENEKEGFPITALREIKILQLLKHE-N 77 Query: 357 VVRLLDL---KQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 VV L+++ K + +YLVF++ + DL + K +K +M L Sbjct: 78 VVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNVL---VKFTLSEIKRVMQMLL 134 Query: 528 KGVAFCH 548 G+ + H Sbjct: 135 NGLYYIH 141
>CDK9_BOVIN (Q5EAB2) Cell division protein kinase 9 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9) Length = 372 Score = 79.0 bits (193), Expect = 9e-15 Identities = 45/127 (35%), Positives = 74/127 (58%), Gaps = 3/127 (2%) Frame = +3 Query: 177 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 356 YEKL K+G+GT+G+V+KA+ + TG+ VALKK + + EG P TALRE+ +L++L + + Sbjct: 19 YEKLAKIGQGTFGEVFKAKHRKTGQKVALKKVLMENEKEGFPITALREIKILQLLKHE-N 77 Query: 357 VVRLLDL---KQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 VV L+++ K + +YLVF++ + DL + K +K +M L Sbjct: 78 VVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNVL---VKFTLSEIKRVMQMLL 134 Query: 528 KGVAFCH 548 G+ + H Sbjct: 135 NGLYYIH 141
>AL2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.11.22)| (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 7 protein) Length = 384 Score = 79.0 bits (193), Expect = 9e-15 Identities = 50/128 (39%), Positives = 74/128 (57%) Frame = +3 Query: 165 AMDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLS 344 A Y LEK+GEG+Y VYK + G++VALK + +EGVP TA+RE SLL+ L Sbjct: 48 AASSYLNLEKLGEGSYATVYKGISRINGQLVALKVISM-NAEEGVPFTAIREASLLKGL- 105 Query: 345 QDPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQL 524 + ++V L D+ + L VFEYM TDL +++ H + H V++ M+QL Sbjct: 106 KHANIVLLHDIIHTKE-----TLTFVFEYMHTDLAQYMSQHPGG---LHPHNVRLFMFQL 157 Query: 525 CKGVAFCH 548 +G+A+ H Sbjct: 158 LRGLAYIH 165
>BUR1_NEUCR (Q871M9) Serine/threonine-protein kinase bur-1 (EC 2.7.11.22) (EC| 2.7.11.23) Length = 545 Score = 78.6 bits (192), Expect = 1e-14 Identities = 48/128 (37%), Positives = 75/128 (58%), Gaps = 4/128 (3%) Frame = +3 Query: 177 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 356 YE L K+GEGT+G+V++AR + TG +VALKK + + +G P TALRE+ LL++LS + Sbjct: 26 YEVLGKLGEGTFGEVHRARSRKTGALVALKKIIMHNERDGFPITALREIKLLKLLSH-KN 84 Query: 357 VVRL----LDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQL 524 V+RL ++ +K + I+Y+V YMD DL + + VK + QL Sbjct: 85 VLRLEEMAIEHPPRTDKRTRPIVYMVTPYMDHDLSGLL---DNPSVRFTEPQVKCYLLQL 141 Query: 525 CKGVAFCH 548 +G+ + H Sbjct: 142 LEGLKYLH 149
>CDKL2_RABIT (Q9TTK0) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| (Serine/threonine-protein kinase KKIAMRE) Length = 566 Score = 78.2 bits (191), Expect = 1e-14 Identities = 49/131 (37%), Positives = 75/131 (57%), Gaps = 4/131 (3%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 M+ YE L VGEG+YG V K R K +GRIVA+KK +DD+ V A+RE+ LL+ L Sbjct: 1 MEKYENLGLVGEGSYGMVMKCRNKDSGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRH 60 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMD----TDLKKFIRGHRQNHQKIPAHTVKILM 515 + ++V LL++ + + + YLVFE++D DL+ F G + V+ + Sbjct: 61 E-NLVNLLEVCKKKKR-----WYLVFEFVDHTILDDLELFPNG-------LDDQVVQKYL 107 Query: 516 YQLCKGVAFCH 548 +Q+ G+ FCH Sbjct: 108 FQIINGIGFCH 118
>CDK7_XENLA (P20911) Cell division protein kinase 7 (EC 2.7.11.22) (EC| 2.7.11.23) (40 kDa protein kinase) (P40 MO15) (CDC2/CDK2,4-activating kinase) Length = 352 Score = 78.2 bits (191), Expect = 1e-14 Identities = 51/127 (40%), Positives = 78/127 (61%), Gaps = 3/127 (2%) Frame = +3 Query: 177 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRL---PEDDEGVPPTALREVSLLRMLSQ 347 YEKL+ +GEG + VYKAR+K T RIVA+KK +L E ++G+ TALRE+ LL+ LS Sbjct: 18 YEKLDFLGEGQFATVYKARDKNTDRIVAIKKIKLGHRAEANDGINRTALREIKLLQELSH 77 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 P+++ LLD ++ + LVF++M+TDL+ I+ + PAH +K M Sbjct: 78 -PNIIGLLDAFGHKSN-----ISLVFDFMETDLEVIIKD--TSLVLTPAH-IKSYMLMTL 128 Query: 528 KGVAFCH 548 +G+ + H Sbjct: 129 QGLEYLH 135
>CCRK_RAT (Q4KM34) Cell cycle-related kinase (EC 2.7.11.22)| Length = 346 Score = 77.0 bits (188), Expect = 3e-14 Identities = 50/127 (39%), Positives = 72/127 (56%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 MD Y L ++GEG +G V+KA+ TG IVALKK L ++G+P ALRE+ L+ + Sbjct: 1 MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGIPNQALREIKALQEIED 60 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 +VV+L + G + L FE+M +DL + +R H Q + + VK + L Sbjct: 61 SQYVVQL----KAVFPHGAGFV-LAFEFMLSDLAEVVR-HAQ--RPLAPAQVKSYLQMLL 112 Query: 528 KGVAFCH 548 KGVAFCH Sbjct: 113 KGVAFCH 119
>CCRK_MOUSE (Q9JHU3) Cell cycle-related kinase (EC 2.7.11.22)| (Cyclin-kinase-activating kinase p42) (CDK-activating kinase p42) (CAK-kinase p42) (CDK-related protein kinase PNQLARE) Length = 346 Score = 77.0 bits (188), Expect = 3e-14 Identities = 50/127 (39%), Positives = 72/127 (56%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 MD Y L ++GEG +G V+KA+ TG IVALKK L ++G+P ALRE+ L+ + Sbjct: 1 MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGIPNQALREIKALQEIED 60 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 +VV+L + G + L FE+M +DL + +R H Q + + VK + L Sbjct: 61 SQYVVQL----KAVFPHGAGFV-LAFEFMLSDLAEVVR-HAQ--RPLAPAQVKSYLQMLL 112 Query: 528 KGVAFCH 548 KGVAFCH Sbjct: 113 KGVAFCH 119
>CDK7_MOUSE (Q03147) Cell division protein kinase 7 (EC 2.7.11.22) (EC| 2.7.11.23) (CDK-activating kinase) (CAK) (TFIIH basal transcription factor complex kinase subunit) (39 kDa protein kinase) (P39 Mo15) (Protein-tyrosine kinase MPK-7) (CR4 protein kinas Length = 346 Score = 76.3 bits (186), Expect = 6e-14 Identities = 48/127 (37%), Positives = 75/127 (59%), Gaps = 3/127 (2%) Frame = +3 Query: 177 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRL---PEDDEGVPPTALREVSLLRMLSQ 347 YEKL+ +GEG + VYKAR+K T +IVA+KK +L E +G+ TALRE+ LL+ LS Sbjct: 12 YEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSH 71 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 P+++ LLD ++ + LVF++M+TDL+ I + N + +K M Sbjct: 72 -PNIIGLLDAFGHKSN-----ISLVFDFMETDLEVII---KDNSLVLTPSHIKAYMLMTL 122 Query: 528 KGVAFCH 548 +G+ + H Sbjct: 123 QGLEYLH 129
>CDK7_HUMAN (P50613) Cell division protein kinase 7 (EC 2.7.11.22) (EC| 2.7.11.23) (CDK-activating kinase) (CAK) (TFIIH basal transcription factor complex kinase subunit) (39 kDa protein kinase) (P39 Mo15) (STK1) (CAK1) Length = 346 Score = 76.3 bits (186), Expect = 6e-14 Identities = 48/127 (37%), Positives = 75/127 (59%), Gaps = 3/127 (2%) Frame = +3 Query: 177 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRL---PEDDEGVPPTALREVSLLRMLSQ 347 YEKL+ +GEG + VYKAR+K T +IVA+KK +L E +G+ TALRE+ LL+ LS Sbjct: 12 YEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSH 71 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 P+++ LLD ++ + LVF++M+TDL+ I + N + +K M Sbjct: 72 -PNIIGLLDAFGHKSN-----ISLVFDFMETDLEVII---KDNSLVLTPSHIKAYMLMTL 122 Query: 528 KGVAFCH 548 +G+ + H Sbjct: 123 QGLEYLH 129
>CCRK_PONPY (Q5R7I7) Cell cycle-related kinase (EC 2.7.11.22)| Length = 346 Score = 75.9 bits (185), Expect = 7e-14 Identities = 49/127 (38%), Positives = 73/127 (57%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 MD Y L ++GEG +G V+KA+ TG IVALKK L ++G+P ALRE+ L+ + Sbjct: 1 MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGIPNQALREIKALQEMED 60 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 + +VV+L + + G L FE+M +DL + +R H Q + + VK + L Sbjct: 61 NQYVVQLKAV--FPHSAG---FVLAFEFMLSDLAEVVR-HAQ--RPLAQAQVKSYLQMLL 112 Query: 528 KGVAFCH 548 KGV+FCH Sbjct: 113 KGVSFCH 119
>CCRK_MACMU (Q5EDC3) Cell cycle-related kinase (EC 2.7.11.22)| (Cyclin-kinase-activating kinase p42) (CDK-activating kinase p42) (CAK-kinase p42) Length = 243 Score = 75.5 bits (184), Expect = 1e-13 Identities = 51/127 (40%), Positives = 72/127 (56%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 MD Y L ++GEG +G V+KA+ TG IVALKK L ++G P ALRE+ L+ + Sbjct: 1 MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMGD 60 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 + +VV+ LK G + L FE+M +DL + +R H Q + + VK + L Sbjct: 61 NQYVVQ---LKAVFPHGGGFV--LAFEFMLSDLAEVVR-HAQ--RPLAQAQVKSYLQMLL 112 Query: 528 KGVAFCH 548 KGVAFCH Sbjct: 113 KGVAFCH 119
>CCRK_HUMAN (Q8IZL9) Cell cycle-related kinase (EC 2.7.11.22)| (Cyclin-kinase-activating kinase p42) (CDK-activating kinase p42) (CAK-kinase p42) Length = 346 Score = 75.5 bits (184), Expect = 1e-13 Identities = 51/127 (40%), Positives = 72/127 (56%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 MD Y L ++GEG +G V+KA+ TG IVALKK L ++G P ALRE+ L+ + Sbjct: 1 MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMED 60 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 + +VV+ LK G + L FE+M +DL + +R H Q + + VK + L Sbjct: 61 NQYVVQ---LKAVFPHGGGFV--LAFEFMLSDLAEVVR-HAQ--RPLAQAQVKSYLQMLL 112 Query: 528 KGVAFCH 548 KGVAFCH Sbjct: 113 KGVAFCH 119
>CDK9_CAEEL (Q9TVL3) Probable cell division protein kinase 9 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9) Length = 478 Score = 74.3 bits (181), Expect = 2e-13 Identities = 46/135 (34%), Positives = 73/135 (54%), Gaps = 5/135 (3%) Frame = +3 Query: 159 LRAMDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRM 338 +R + YEKL K+G+GT+G+V+KAR K TGR+VALKK + + EG P TALREV +L Sbjct: 79 IRDVSTYEKLNKIGQGTFGEVFKARCKNTGRMVALKKILMENEKEGFPITALREVKMLEQ 138 Query: 339 LSQDPHVVRLLDLKQGQN-----KEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTV 503 L + P++ L+++ ++ + + YLV DL + + + + Sbjct: 139 L-KHPNITDLIEVCSAKSTGTTGSKDRATFYLVMALCAHDLAGLLSNPKIRMSLV---HI 194 Query: 504 KILMYQLCKGVAFCH 548 K +M L G+ H Sbjct: 195 KTMMKHLMSGLNKLH 209
>CDK7_RAT (P51952) Cell division protein kinase 7 (EC 2.7.11.22) (EC| 2.7.11.23) (CDK-activating kinase) (CAK) (TFIIH basal transcription factor complex kinase subunit) (39 protein kinase) (P39 Mo15) (Fragment) Length = 329 Score = 73.6 bits (179), Expect = 4e-13 Identities = 47/126 (37%), Positives = 74/126 (58%), Gaps = 3/126 (2%) Frame = +3 Query: 180 EKLEKVGEGTYGKVYKAREKATGRIVALKKTRL---PEDDEGVPPTALREVSLLRMLSQD 350 EKL+ +GEG + VYKAR+K T +IVA+KK +L E +G+ TALRE+ LL+ LS Sbjct: 5 EKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSH- 63 Query: 351 PHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLCK 530 P+++ LLD ++ + LVF++M+TDL+ I + N + +K M + Sbjct: 64 PNIIGLLDAFGHKSN-----ISLVFDFMETDLEVII---KDNSLVLTPSHIKAYMLMTLQ 115 Query: 531 GVAFCH 548 G+ + H Sbjct: 116 GLEYLH 121
>CDK7_DICDI (P54685) Cell division protein kinase 7 (EC 2.7.11.22) (EC| 2.7.11.23) (CDK-activating kinase) (CAK) (MO15 homolog) Length = 362 Score = 71.2 bits (173), Expect = 2e-12 Identities = 49/131 (37%), Positives = 72/131 (54%), Gaps = 4/131 (3%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTR----LPEDDEGVPPTALREVSLLR 335 MD Y +GEGTYG V +A KATG+IVA+KK R + D+G+ +A+RE+ +L+ Sbjct: 1 MDKYNIEALIGEGTYGVVSRATVKATGQIVAIKKIRKILIQNQTDDGINFSAIREIKILQ 60 Query: 336 MLSQDPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILM 515 L D +VV LLD+ ++ +YLVFE M DL++ I + +K M Sbjct: 61 ELKHD-NVVNLLDIFAHKSN-----VYLVFELMQWDLQEVI---EDKSIILKPADIKSYM 111 Query: 516 YQLCKGVAFCH 548 L +G+ CH Sbjct: 112 KMLLQGIEACH 122
>CDK9_SCHPO (Q96WV9) Serine/threonine-protein kinase cdk9 (EC 2.7.11.1)| (Cyclin-dependent kinase cdk9) Length = 591 Score = 70.9 bits (172), Expect = 2e-12 Identities = 39/127 (30%), Positives = 69/127 (54%), Gaps = 3/127 (2%) Frame = +3 Query: 177 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 356 Y +EK+GEGT+G+VYK++ + G++ ALK+ + + EG P TA+RE+ +L+ + + + Sbjct: 36 YHLMEKLGEGTFGEVYKSQRRKDGKVYALKRILMHTEKEGFPITAIREIKILKSIKHE-N 94 Query: 357 VVRLLDL---KQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 ++ L D+ + + + +Y+V YMD DL + K +K M QL Sbjct: 95 IIPLSDMTVVRADKKHRRRGSIYMVTPYMDHDLSGLL---ENPSVKFTEPQIKCYMKQLF 151 Query: 528 KGVAFCH 548 G + H Sbjct: 152 AGTKYLH 158
>MK15_HUMAN (Q8TD08) Mitogen-activated protein kinase 15 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 8) Length = 544 Score = 70.9 bits (172), Expect = 2e-12 Identities = 45/131 (34%), Positives = 70/131 (53%), Gaps = 2/131 (1%) Frame = +3 Query: 162 RAMDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 341 R + Y ++G+G YG V+KA ++ TG +VA+KK D+ RE++LL+ Sbjct: 8 RIVRRYLLRRQLGQGAYGIVWKAVDRRTGEVVAIKKIFDAFRDKTDAQRTFREITLLQEF 67 Query: 342 SQDPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIR--GHRQNHQKIPAHTVKILM 515 P+++ LLD+ + +N +YLVFE+MDTDL IR G Q+ V+ + Sbjct: 68 GDHPNIISLLDVIRAENDRD---IYLVFEFMDTDLNAVIRKGGLLQDVH------VRSIF 118 Query: 516 YQLCKGVAFCH 548 YQL + F H Sbjct: 119 YQLLRATRFLH 129
>MK12_MOUSE (O08911) Mitogen-activated protein kinase 12 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 6) (ERK-6) (Stress-activated protein kinase 3) (Mitogen-activated protein kinase p38 gamma) (MAP kinase p38 gamma) Length = 367 Score = 70.1 bits (170), Expect = 4e-12 Identities = 43/129 (33%), Positives = 69/129 (53%), Gaps = 1/129 (0%) Frame = +3 Query: 174 LYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDP 353 +Y+ L+ VG G YG V A + TG VA+KK P E A RE+ LL+ + + Sbjct: 26 VYQDLQPVGSGAYGAVCSAVDSRTGNKVAIKKLYRPFQSELFAKRAYRELRLLKHMRHE- 84 Query: 354 HVVRLLDL-KQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLCK 530 +V+ LLD+ ++ + T YLV +M TDL K ++ H+ + ++ L+YQ+ K Sbjct: 85 NVIGLLDVFTPDESLDDFTDFYLVMPFMGTDLGKLMK-----HETLSEDRIQFLVYQMLK 139 Query: 531 GVAFCHGRG 557 G+ + H G Sbjct: 140 GLKYIHAAG 148
>MK15_RAT (Q9Z2A6) Mitogen-activated protein kinase 15 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 7) Length = 547 Score = 69.7 bits (169), Expect = 5e-12 Identities = 42/119 (35%), Positives = 63/119 (52%) Frame = +3 Query: 192 KVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPHVVRLL 371 ++G+G YG V+KA ++ TG +VA+KK D+ RE+ LLR P+++RLL Sbjct: 19 RLGKGAYGIVWKAMDRRTGEVVAIKKIFDAFRDQTDAQRTFREIMLLREFGGHPNIIRLL 78 Query: 372 DLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLCKGVAFCH 548 D+ +N +YLVFE MDTDL I Q + + + + YQL + F H Sbjct: 79 DVIPAKNDRD---IYLVFESMDTDLNAVI----QKGRLLEDIHKRCIFYQLLRATKFIH 130
>MK12_RAT (Q63538) Mitogen-activated protein kinase 12 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 6) (ERK-6) (Stress-activated protein kinase 3) (Mitogen-activated protein kinase p38 gamma) (MAP kinase p38 gamma) Length = 367 Score = 69.7 bits (169), Expect = 5e-12 Identities = 43/129 (33%), Positives = 68/129 (52%), Gaps = 1/129 (0%) Frame = +3 Query: 174 LYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDP 353 +Y+ L+ VG G YG V A + TG VA+KK P E A RE+ LL+ + + Sbjct: 26 VYQDLQPVGSGAYGAVCSAVDSRTGNKVAIKKLYRPFQSELFAKRAYRELRLLKHMRHE- 84 Query: 354 HVVRLLDL-KQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLCK 530 +V+ LLD+ + + T YLV +M TDL K ++ H+ + ++ L+YQ+ K Sbjct: 85 NVIGLLDVFTPDETLDDFTDFYLVMPFMGTDLGKLMK-----HETLSEDRIQFLVYQMLK 139 Query: 531 GVAFCHGRG 557 G+ + H G Sbjct: 140 GLKYIHAAG 148
>MK12_HUMAN (P53778) Mitogen-activated protein kinase 12 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 6) (ERK-6) (ERK5) (Stress-activated protein kinase 3) (Mitogen-activated protein kinase p38 gamma) (MAP kinase p38 gamma) Length = 367 Score = 69.7 bits (169), Expect = 5e-12 Identities = 44/129 (34%), Positives = 68/129 (52%), Gaps = 1/129 (0%) Frame = +3 Query: 174 LYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDP 353 +Y L+ VG G YG V A + TG VA+KK P E A RE+ LL+ + + Sbjct: 26 VYRDLQPVGSGAYGAVCSAVDGRTGAKVAIKKLYRPFQSELFAKRAYRELRLLKHMRHE- 84 Query: 354 HVVRLLDL-KQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLCK 530 +V+ LLD+ + + T YLV +M TDL K ++ H+K+ ++ L+YQ+ K Sbjct: 85 NVIGLLDVFTPDETLDDFTDFYLVMPFMGTDLGKLMK-----HEKLGEDRIQFLVYQMLK 139 Query: 531 GVAFCHGRG 557 G+ + H G Sbjct: 140 GLRYIHAAG 148
>CRK1_SCHPO (Q12126) Serine/threonine-protein kinase crk1 (EC 2.7.11.23)| (Mitotic catastrophe suppressor 6) Length = 335 Score = 69.3 bits (168), Expect = 7e-12 Identities = 45/126 (35%), Positives = 72/126 (57%) Frame = +3 Query: 177 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 356 Y K KVGEGTY V+ R+K T R VA+KK ++ + +G+ +ALRE+ LR S+ + Sbjct: 11 YVKERKVGEGTYAVVFLGRQKETNRRVAIKKIKVGQFKDGIDISALREIKFLRE-SRHDN 69 Query: 357 VVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLCKGV 536 V+ L+D+ ++ L ++ E++D+DL+ I+ Q PAH +K M L +G+ Sbjct: 70 VIELVDVFSTKSN-----LNIILEFLDSDLEMLIKDKFIVFQ--PAH-IKSWMVMLLRGL 121 Query: 537 AFCHGR 554 H R Sbjct: 122 HHIHSR 127
>MK15_MOUSE (Q80Y86) Mitogen-activated protein kinase 15 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 7) Length = 549 Score = 67.8 bits (164), Expect = 2e-11 Identities = 41/119 (34%), Positives = 63/119 (52%) Frame = +3 Query: 192 KVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPHVVRLL 371 ++G+G YG V+KA ++ TG +VA+KK D+ RE+ LL+ P+++RLL Sbjct: 19 RLGKGAYGIVWKAMDRRTGEVVAIKKIFDAFRDQIDAQRTFREIMLLKEFGGHPNIIRLL 78 Query: 372 DLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLCKGVAFCH 548 D+ +N +YLVFE MDTDL I Q + + + + YQL + F H Sbjct: 79 DVIPAKNDRD---IYLVFESMDTDLNAVI----QKGRLLKDIHKRCIFYQLLRATKFIH 130
>KIN28_YEAST (P06242) Serine/threonine-protein kinase KIN28 (EC 2.7.11.23)| Length = 306 Score = 67.0 bits (162), Expect = 3e-11 Identities = 44/124 (35%), Positives = 70/124 (56%) Frame = +3 Query: 177 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 356 Y K +KVGEGTY VY + +TGR +A+K+ + E +G+ +A+REV L+ + Q P+ Sbjct: 7 YTKEKKVGEGTYAVVYLGCQHSTGRKIAIKEIKTSEFKDGLDMSAIREVKYLQEM-QHPN 65 Query: 357 VVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLCKGV 536 V+ L+D+ + L LV E++ TDL+ I+ ++ PA +K M +GV Sbjct: 66 VIELIDIFMAYDN-----LNLVLEFLPTDLEVVIKD--KSILFTPA-DIKAWMLMTLRGV 117 Query: 537 AFCH 548 CH Sbjct: 118 YHCH 121
>CDC2_PETHY (P43290) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) (Fragment) Length = 90 Score = 67.0 bits (162), Expect = 3e-11 Identities = 38/86 (44%), Positives = 56/86 (65%) Frame = +3 Query: 291 EGVPPTALREVSLLRMLSQDPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHR 470 EGVP TA+RE+SLL+ + Q ++VRL D+ + + LYLVFEY+D DLKK + Sbjct: 1 EGVPSTAIREISLLKEM-QHANIVRLQDVVHSEKR-----LYLVFEYLDLDLKKHMDSSP 54 Query: 471 QNHQKIPAHTVKILMYQLCKGVAFCH 548 + K P VK+ +YQ+ +G+A+CH Sbjct: 55 E-FSKDP-RLVKMFLYQILRGIAYCH 78
>BUR1_CANAL (Q9Y7W4) Serine/threonine-protein kinase BUR1 (EC 2.7.11.22) (EC| 2.7.11.23) Length = 746 Score = 66.6 bits (161), Expect = 4e-11 Identities = 42/134 (31%), Positives = 72/134 (53%), Gaps = 8/134 (5%) Frame = +3 Query: 177 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 356 YE +EK+G+GT+G V KA+ K G +VA+K+ EG P TA+RE+++L+ L+ + Sbjct: 44 YEVIEKLGQGTFGVVQKAKSKKDGSLVAIKQLINHSAKEGFPITAMREITILKQLNH-KN 102 Query: 357 VVRLLDL-----KQGQNKEGQTI---LYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKIL 512 ++ + D+ K + T+ Y V YM +DL + + K+ +K + Sbjct: 103 ILTIQDMIFEEPKMSNRTDIITMRGSFYTVTPYMSSDLVGLLENPK---IKLELGQIKCI 159 Query: 513 MYQLCKGVAFCHGR 554 M QL KG+ + H + Sbjct: 160 MQQLLKGIQYVHNQ 173
>MK12_BRARE (O42376) Mitogen-activated protein kinase 12 (EC 2.7.11.24)| (Stress-activated protein kinase 3) Length = 363 Score = 66.2 bits (160), Expect = 6e-11 Identities = 43/130 (33%), Positives = 70/130 (53%), Gaps = 1/130 (0%) Frame = +3 Query: 171 DLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQD 350 D Y+ L++VG G YG V A ++ TG VA+KK P + A RE+ LL+ + D Sbjct: 23 DRYKDLKQVGTGAYGTVCYALDRRTGAKVAIKKLHRPFQSDLFAKRAYRELRLLKHMKHD 82 Query: 351 PHVVRLLDLKQGQ-NKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 +V+ L+D+ + + YLV +M TDL K ++ R + ++ V+ L+YQ+ Sbjct: 83 -NVIGLVDVFTADLSLDRFHDFYLVMPFMGTDLGKLMKMERLSEER-----VQYLVYQML 136 Query: 528 KGVAFCHGRG 557 KG+ + H G Sbjct: 137 KGLKYIHAAG 146
>CDK7_CARAU (P51953) Cell division protein kinase 7 (EC 2.7.11.22) (EC| 2.7.11.23) (40 kDa protein kinase) (P40 MO15) (CDC2/CDK2,4-activating kinase) Length = 344 Score = 65.5 bits (158), Expect = 1e-10 Identities = 42/99 (42%), Positives = 63/99 (63%), Gaps = 3/99 (3%) Frame = +3 Query: 174 LYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRL---PEDDEGVPPTALREVSLLRMLS 344 LYEKL+ +GEG + VYKAR+K T IVA+KK ++ E +G+ TALRE+ LL+ LS Sbjct: 11 LYEKLDFLGEGQFATVYKARDKTTNTIVAIKKIKVGHRTEAKDGINRTALREIKLLQELS 70 Query: 345 QDPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIR 461 P+++ LLD +K ++L +M+TDL+ I+ Sbjct: 71 H-PNIIGLLD--AFGHKSNISLLC----FMETDLEVIIK 102
>MK14A_DROME (O62618) Mitogen-activated protein kinase 14A (EC 2.7.11.24) (MAP| kinase p38a) (p38 MAPK) (Dp38) (D-p38a) Length = 366 Score = 62.8 bits (151), Expect = 6e-10 Identities = 43/133 (32%), Positives = 64/133 (48%), Gaps = 4/133 (3%) Frame = +3 Query: 171 DLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQD 350 D+Y+ L+ VG G YG+V KA + T VA+KK P RE+ LL+ + + Sbjct: 23 DIYQDLQPVGSGAYGQVSKAVVRGTNMHVAIKKLARPFQSAVHAKRTYRELRLLKHMDHE 82 Query: 351 PHVVRLLDLKQGQNKEGQ----TILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMY 518 +V+ LLD+ G +YLV MD DL IR Q + V+ L+Y Sbjct: 83 -NVIGLLDIFHPHPANGSLENFQQVYLVTHLMDADLNNIIR-----MQHLSDDHVQFLVY 136 Query: 519 QLCKGVAFCHGRG 557 Q+ +G+ + H G Sbjct: 137 QILRGLKYIHSAG 149
>MPK5_ARATH (Q39025) Mitogen-activated protein kinase homolog 5 (EC 2.7.11.24)| (MAP kinase 5) (AtMPK5) Length = 376 Score = 62.4 bits (150), Expect = 8e-10 Identities = 39/121 (32%), Positives = 64/121 (52%) Frame = +3 Query: 186 LEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPHVVR 365 + +G G YG V A + T +A+KK D++ LRE+ LLR L + +VV Sbjct: 46 IRPIGRGAYGFVCAAVDSETHEEIAIKKIGKAFDNKVDAKRTLREIKLLRHLEHE-NVVV 104 Query: 366 LLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLCKGVAFC 545 + D+ + KE +Y+VFE MDTDL + IR ++Q + + +YQ+ +G+ + Sbjct: 105 IKDIIRPPKKEDFVDVYIVFELMDTDLHQIIR----SNQSLNDDHCQYFLYQILRGLKYI 160 Query: 546 H 548 H Sbjct: 161 H 161
>BUR1_DEBHA (Q6BV06) Serine/threonine-protein kinase BUR1 (EC 2.7.11.22) (EC| 2.7.11.23) Length = 608 Score = 62.4 bits (150), Expect = 8e-10 Identities = 42/132 (31%), Positives = 71/132 (53%), Gaps = 8/132 (6%) Frame = +3 Query: 177 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 356 YE ++K+G+GT+G V KAR T +VALK+ EG P TA+RE+++L+ L+ + Sbjct: 39 YEIIQKLGQGTFGVVQKARNIKTKELVALKQLINHSAKEGFPITAMREITILKKLNH-KN 97 Query: 357 VVRLLDL--KQGQNKEGQTIL------YLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKIL 512 +++++D+ ++ + Q IL Y V YM +DL + N + +K Sbjct: 98 ILKIIDMIYEEPKISNPQDILHQRGCFYTVSPYMCSDLVGLLENPNIN---LEVSHIKCF 154 Query: 513 MYQLCKGVAFCH 548 M QL G+ + H Sbjct: 155 MEQLLHGIQYIH 166
>MPK4_ARATH (Q39024) Mitogen-activated protein kinase homolog 4 (EC 2.7.11.24)| (MAP kinase 4) (AtMPK4) Length = 376 Score = 62.0 bits (149), Expect = 1e-09 Identities = 38/121 (31%), Positives = 63/121 (52%) Frame = +3 Query: 186 LEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPHVVR 365 L +G G YG V A TG VA+KK D+ LRE+ LL+ + + +V+ Sbjct: 46 LRPIGRGAYGIVCAATNSETGEEVAIKKIGNAFDNIIDAKRTLREIKLLKHMDHE-NVIA 104 Query: 366 LLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLCKGVAFC 545 + D+ + +E +Y+V+E MDTDL + IR ++Q + + +YQL +G+ + Sbjct: 105 VKDIIKPPQRENFNDVYIVYELMDTDLHQIIR----SNQPLTDDHCRFFLYQLLRGLKYV 160 Query: 546 H 548 H Sbjct: 161 H 161
>CDK8_DROME (Q9VT57) Cell division protein kinase 8 (EC 2.7.11.22) (EC| 2.7.11.23) (DmCdk8) Length = 454 Score = 61.6 bits (148), Expect = 1e-09 Identities = 44/126 (34%), Positives = 67/126 (53%), Gaps = 7/126 (5%) Frame = +3 Query: 192 KVGEGTYGKVYKAREKAT--GRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPHVVR 365 KVG GTYG VYKA+ K T G+ ALK+ D G+ +A RE++LLR L +V+ Sbjct: 26 KVGRGTYGHVYKAKWKETSDGKEYALKQI----DGTGLSMSACREIALLRELKHQ-NVIT 80 Query: 366 LLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHR-----QNHQKIPAHTVKILMYQLCK 530 L+ + N ++L+ +Y + DL I+ HR + +P VK L+YQ+ Sbjct: 81 LIRVFLSHNDRK---VFLLIDYAEHDLWHIIKFHRAAKATKKQVVVPRGMVKSLLYQILD 137 Query: 531 GVAFCH 548 G+ + H Sbjct: 138 GIHYLH 143
>KSG4_ARATH (Q9FVS6) Shaggy-related protein kinase delta (EC 2.7.11.1)| (ASK-delta) Length = 420 Score = 61.6 bits (148), Expect = 1e-09 Identities = 35/118 (29%), Positives = 66/118 (55%) Frame = +3 Query: 195 VGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPHVVRLLD 374 VG G++G V++A+ + TG +VA+KK + + RE+ +++ML P+VV L Sbjct: 88 VGTGSFGMVFQAKCRETGEVVAIKKVLQDKRYKN------RELQIMQMLDH-PNVVCLKH 140 Query: 375 LKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLCKGVAFCH 548 + + + L LV E++ + + R + + +Q +P VK+ YQ+C+G+A+ H Sbjct: 141 SFYSRTENEEVYLNLVLEFVPETVNRTARSYSRMNQLMPLIYVKLYTYQICRGLAYLH 198
>CD2L6_MOUSE (Q8BWD8) Cell division cycle 2-like protein kinase 6 (EC 2.7.11.22)| (CDC2-related protein kinase 6) Length = 501 Score = 61.6 bits (148), Expect = 1e-09 Identities = 49/139 (35%), Positives = 74/139 (53%), Gaps = 10/139 (7%) Frame = +3 Query: 162 RAMDLYEKLE-KVGEGTYGKVYKAREK--ATGRIVALKKTRLPEDDEGVPPTALREVSLL 332 R DL+E KVG GTYG VYKAR K + ALK+ + G+ +A RE++LL Sbjct: 15 RVEDLFEYEGCKVGRGTYGHVYKARRKDGKDEKEYALKQI----EGTGISMSACREIALL 70 Query: 333 RMLSQDPHVVRL--LDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHR-----QNHQKIP 491 R L + P+V+ L + L K ++L+F+Y + DL I+ HR + ++P Sbjct: 71 REL-KHPNVIALQKVFLSHSDRK-----VWLLFDYAEHDLWHIIKFHRASKANKKPMQLP 124 Query: 492 AHTVKILMYQLCKGVAFCH 548 VK L+YQ+ G+ + H Sbjct: 125 RSMVKSLLYQILDGIHYLH 143
>CD2L6_HUMAN (Q9BWU1) Cell division cycle 2-like protein kinase 6 (EC 2.7.11.22)| (CDC2-related protein kinase 6) (Death-preventing kinase) (Cyclin-dependent kinase 11) Length = 502 Score = 61.6 bits (148), Expect = 1e-09 Identities = 49/139 (35%), Positives = 74/139 (53%), Gaps = 10/139 (7%) Frame = +3 Query: 162 RAMDLYEKLE-KVGEGTYGKVYKAREK--ATGRIVALKKTRLPEDDEGVPPTALREVSLL 332 R DL+E KVG GTYG VYKAR K + ALK+ + G+ +A RE++LL Sbjct: 15 RVEDLFEYEGCKVGRGTYGHVYKARRKDGKDEKEYALKQI----EGTGISMSACREIALL 70 Query: 333 RMLSQDPHVVRL--LDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHR-----QNHQKIP 491 R L + P+V+ L + L K ++L+F+Y + DL I+ HR + ++P Sbjct: 71 REL-KHPNVIALQKVFLSHSDRK-----VWLLFDYAEHDLWHIIKFHRASKANKKPMQLP 124 Query: 492 AHTVKILMYQLCKGVAFCH 548 VK L+YQ+ G+ + H Sbjct: 125 RSMVKSLLYQILDGIHYLH 143
>MK14B_DROME (O61443) Mitogen-activated protein kinase 14B (EC 2.7.11.24) (MAP| kinase p38b) (D-p38b) Length = 365 Score = 61.6 bits (148), Expect = 1e-09 Identities = 41/133 (30%), Positives = 67/133 (50%), Gaps = 4/133 (3%) Frame = +3 Query: 171 DLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQD 350 + Y+ L+ VG+G YG+V KA + T VA+KK P RE+ LL+ + + Sbjct: 22 ETYQNLQPVGQGAYGQVCKAVVRGTSTKVAIKKLARPFQSAVHAKRTYRELRLLKHMDHE 81 Query: 351 PHVVRLLDL----KQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMY 518 +V+ LLD+ + + + +Y+V MD DL IR QK+ V+ L+Y Sbjct: 82 -NVIGLLDVFHPGQPADSLDQFQQVYMVTHLMDADLNNIIR-----TQKLSDDHVQFLVY 135 Query: 519 QLCKGVAFCHGRG 557 Q+ +G+ + H G Sbjct: 136 QILRGLKYIHSAG 148
>MK14C_DROME (P83100) Putative mitogen-activated protein kinase 14C (EC| 2.7.11.24) (MAP kinase p38c) Length = 356 Score = 61.2 bits (147), Expect = 2e-09 Identities = 39/131 (29%), Positives = 69/131 (52%), Gaps = 2/131 (1%) Frame = +3 Query: 171 DLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQD 350 D+YE + +G G++G+V K R + T A+K+ P + E RE+ LL+ ++ Sbjct: 18 DIYEFVRFLGGGSFGQVAKVRLRGTENYFAMKRLMRPFEREEDAKGTYREIRLLKHMNHR 77 Query: 351 PHVVRLLDL--KQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQL 524 +V+ LL++ N +YLV MD DL ++ R R + Q+I +I++YQ+ Sbjct: 78 -NVISLLNVFHPPAHNMMEFQQVYLVTHLMDADLHRYSRSKRMSDQEI-----RIILYQI 131 Query: 525 CKGVAFCHGRG 557 +G+ + H G Sbjct: 132 LRGLKYIHSAG 142
>KSS1_YEAST (P14681) Mitogen-activated protein kinase KSS1 (EC 2.7.11.24) (MAP| kinase KSS1) (Kinase suppressor of SST2) Length = 368 Score = 61.2 bits (147), Expect = 2e-09 Identities = 36/124 (29%), Positives = 62/124 (50%) Frame = +3 Query: 177 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 356 Y+ ++ +GEG YG V A K +G VA+KK + P + +RE+ LLR + + Sbjct: 13 YKLVDLIGEGAYGTVCSAIHKPSGIKVAIKKIQ-PFSKKLFVTRTIREIKLLRYFHEHEN 71 Query: 357 VVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLCKGV 536 ++ +LD + + + +YLV E M+TDL+K I + V+ YQ+ + + Sbjct: 72 IISILDKVRPVSIDKLNAVYLVEELMETDLQKVINNQNSGFSTLSDDHVQYFTYQILRAL 131 Query: 537 AFCH 548 H Sbjct: 132 KSIH 135
>MK13_RAT (Q9WTY9) Mitogen-activated protein kinase 13 (EC 2.7.11.24)| (Stress-activated protein kinase 4) (Mitogen-activated protein kinase p38 delta) (MAP kinase p38 delta) Length = 366 Score = 60.8 bits (146), Expect = 2e-09 Identities = 44/122 (36%), Positives = 63/122 (51%), Gaps = 1/122 (0%) Frame = +3 Query: 195 VGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPHVVRLLD 374 VG G YG V A +K TG VA+KK P E A RE+ LL+ + + +V+ LLD Sbjct: 31 VGSGAYGAVCSAIDKRTGEKVAIKKLSRPFQSEIFAKRAYRELLLLKHMHHE-NVIGLLD 89 Query: 375 L-KQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLCKGVAFCHG 551 + + YLV +M TDL+K I G + +K V+ L+YQ+ KG+ + H Sbjct: 90 VYTPATSVRNFQDFYLVMPFMQTDLQK-IMGMEFSEEK-----VQYLVYQMLKGLKYIHS 143 Query: 552 RG 557 G Sbjct: 144 AG 145
>MSK3_MEDSA (P51139) Glycogen synthase kinase-3 homolog MsK-3 (EC 2.7.11.1)| Length = 411 Score = 60.5 bits (145), Expect = 3e-09 Identities = 36/118 (30%), Positives = 64/118 (54%) Frame = +3 Query: 195 VGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPHVVRLLD 374 VG G++G V++A+ TG VA+KK + + RE+ +R+L P+VV L Sbjct: 80 VGHGSFGVVFQAKCLETGETVAIKKVLQDKRYKN------RELQTMRLLDH-PNVVSLKH 132 Query: 375 LKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLCKGVAFCH 548 ++ + L LV EY+ + + IR + + +Q++P VK+ YQ+C+ +A+ H Sbjct: 133 CFFSTTEKDELYLNLVLEYVPETVSRVIRHYNKMNQRMPMIYVKLYSYQICRALAYIH 190
>MK13_HUMAN (O15264) Mitogen-activated protein kinase 13 (EC 2.7.11.24)| (Stress-activated protein kinase 4) (Mitogen-activated protein kinase p38 delta) (MAP kinase p38 delta) Length = 365 Score = 60.5 bits (145), Expect = 3e-09 Identities = 44/122 (36%), Positives = 63/122 (51%), Gaps = 1/122 (0%) Frame = +3 Query: 195 VGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPHVVRLLD 374 VG G YG V A +K +G VA+KK P E A RE+ LL+ + Q +V+ LLD Sbjct: 31 VGSGAYGSVCSAIDKRSGEKVAIKKLSRPFQSEIFAKRAYRELLLLKHM-QHENVIGLLD 89 Query: 375 L-KQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLCKGVAFCHG 551 + + YLV +M TDL+K I G + +KI + L+YQ+ KG+ + H Sbjct: 90 VFTPASSLRNFYDFYLVMPFMQTDLQK-IMGMEFSEEKI-----QYLVYQMLKGLKYIHS 143 Query: 552 RG 557 G Sbjct: 144 AG 145
>MAK_MOUSE (Q04859) Serine/threonine-protein kinase MAK (EC 2.7.11.22) (Male| germ cell-associated kinase) (Protein kinase RCK) Length = 622 Score = 60.5 bits (145), Expect = 3e-09 Identities = 40/132 (30%), Positives = 73/132 (55%), Gaps = 2/132 (1%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALK--KTRLPEDDEGVPPTALREVSLLRML 341 M+ Y ++++G+GTYG V + +G +VA+K K + DE + LREV L+ L Sbjct: 1 MNRYTTMKQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECM---NLREVKSLKKL 57 Query: 342 SQDPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQ 521 + +V++L ++ + + LY VFEYM +L + + + ++ P ++ +MYQ Sbjct: 58 NH-ANVIKLKEVIRENDH-----LYFVFEYMKENLYQLM---KDRNKLFPESVIRNIMYQ 108 Query: 522 LCKGVAFCHGRG 557 + +G+AF H G Sbjct: 109 ILQGLAFIHKHG 120
>CDK8_HUMAN (P49336) Cell division protein kinase 8 (EC 2.7.11.22) (EC| 2.7.11.23) (Protein kinase K35) Length = 464 Score = 60.1 bits (144), Expect = 4e-09 Identities = 48/139 (34%), Positives = 74/139 (53%), Gaps = 10/139 (7%) Frame = +3 Query: 162 RAMDLYEKLE-KVGEGTYGKVYKAREK--ATGRIVALKKTRLPEDDEGVPPTALREVSLL 332 R DL+E KVG GTYG VYKA+ K + ALK+ + G+ +A RE++LL Sbjct: 15 RVEDLFEYEGCKVGRGTYGHVYKAKRKDGKDDKDYALKQI----EGTGISMSACREIALL 70 Query: 333 RMLSQDPHVVRL--LDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQ-----KIP 491 R L + P+V+ L + L K ++L+F+Y + DL I+ HR + ++P Sbjct: 71 REL-KHPNVISLQKVFLSHADRK-----VWLLFDYAEHDLWHIIKFHRASKANKKPVQLP 124 Query: 492 AHTVKILMYQLCKGVAFCH 548 VK L+YQ+ G+ + H Sbjct: 125 RGMVKSLLYQILDGIHYLH 143
>ERK1_CANAL (P28869) Extracellular signal-regulated kinase 1 (EC 2.7.11.24)| (ERK1) (MAP kinase 1) (MAPK 1) Length = 417 Score = 60.1 bits (144), Expect = 4e-09 Identities = 51/185 (27%), Positives = 86/185 (46%), Gaps = 11/185 (5%) Frame = +3 Query: 27 HQITRLARQPTREREREKARICATATLQHQNQGAAAPMXXXXXX-----------LRAMD 173 HQ+ + +Q +++ + A+ A A Q Q Q AAA D Sbjct: 8 HQLQQQHQQQMLQQQAQ-AQAQAQAQAQQQQQAAAAAAAANAAATTSSSSPRQVSFNVSD 66 Query: 174 LYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDP 353 Y+ LE VGEG YG V A K + + VA+KK P + + LRE+ LL+ + + Sbjct: 67 HYQILEIVGEGAYGIVCSAIHKPSQQKVAIKKIE-PFERSMLCLRTLRELKLLKHFNHE- 124 Query: 354 HVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLCKG 533 +++ +L +++ N E +YL+ E M+TDL + IR Q + ++ +YQ + Sbjct: 125 NIISILAIQRPINYESFNEIYLIQELMETDLHRVIR-----TQNLSDDHIQYFIYQTLRA 179 Query: 534 VAFCH 548 + H Sbjct: 180 LKAMH 184
>MK13_MOUSE (Q9Z1B7) Mitogen-activated protein kinase 13 (EC 2.7.11.24)| (Stress-activated protein kinase 4) (Mitogen-activated protein kinase p38 delta) (MAP kinase p38 delta) Length = 366 Score = 60.1 bits (144), Expect = 4e-09 Identities = 44/122 (36%), Positives = 62/122 (50%), Gaps = 1/122 (0%) Frame = +3 Query: 195 VGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPHVVRLLD 374 VG G YG V A +K TG VA+KK P E A RE+ LL+ + + +V+ LLD Sbjct: 31 VGSGAYGAVCSAIDKRTGEKVAIKKLSRPFQSEIFAKRAYRELLLLKHMHHE-NVIGLLD 89 Query: 375 L-KQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLCKGVAFCHG 551 + + YLV +M TDL+K I G + K V+ L+YQ+ KG+ + H Sbjct: 90 VFTPASSLRSFHDFYLVMPFMQTDLQK-IMGMEFSEDK-----VQYLVYQMLKGLKYIHS 143 Query: 552 RG 557 G Sbjct: 144 AG 145
>ICK_RAT (Q62726) Serine/threonine-protein kinase ICK (EC 2.7.11.22)| (Intestinal cell kinase) (MAK-related kinase) (MRK) Length = 629 Score = 60.1 bits (144), Expect = 4e-09 Identities = 38/130 (29%), Positives = 72/130 (55%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 M+ Y ++++G+GTYG V R +G ++A+KK + + LREV L+ L+ Sbjct: 1 MNRYTTIKQLGDGTYGSVLLGRSIESGELIAIKKMK-RKFYSWEECMNLREVKSLKKLNH 59 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 ++V+L ++ + + LY +FEYM +L + I ++ ++ P ++ +MYQ+ Sbjct: 60 -ANIVKLKEVIRENDH-----LYFIFEYMKENLYQLI---KERNKLFPESAIRNIMYQIL 110 Query: 528 KGVAFCHGRG 557 +G+AF H G Sbjct: 111 QGLAFIHKHG 120
>ICK_MOUSE (Q9JKV2) Serine/threonine-protein kinase ICK (EC 2.7.11.22)| (Intestinal cell kinase) (mICK) (MAK-related kinase) (MRK) Length = 629 Score = 60.1 bits (144), Expect = 4e-09 Identities = 38/130 (29%), Positives = 72/130 (55%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 M+ Y ++++G+GTYG V R +G ++A+KK + + LREV L+ L+ Sbjct: 1 MNRYTTIKQLGDGTYGSVLLGRSIESGELIAIKKMK-RKFYSWEECMNLREVKSLKKLNH 59 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 ++V+L ++ + + LY +FEYM +L + I ++ ++ P ++ +MYQ+ Sbjct: 60 -ANIVKLKEVIRENDH-----LYFIFEYMKENLYQLI---KERNKLFPESAIRNIMYQIL 110 Query: 528 KGVAFCHGRG 557 +G+AF H G Sbjct: 111 QGLAFIHKHG 120
>ICK_HUMAN (Q9UPZ9) Serine/threonine-protein kinase ICK (EC 2.7.11.22)| (Intestinal cell kinase) (hICK) (MAK-related kinase) (MRK) (Laryngeal cancer kinase 2) (LCK2) Length = 632 Score = 60.1 bits (144), Expect = 4e-09 Identities = 39/130 (30%), Positives = 71/130 (54%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 M+ Y + ++G+GTYG V R +G ++A+KK + + LREV L+ L+ Sbjct: 1 MNRYTTIRQLGDGTYGSVLLGRSIESGELIAIKKMK-RKFYSWEECMNLREVKSLKKLNH 59 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 +VV+L ++ + + LY +FEYM +L + I ++ ++ P ++ +MYQ+ Sbjct: 60 -ANVVKLKEVIRENDH-----LYFIFEYMKENLYQLI---KERNKLFPESAIRNIMYQIL 110 Query: 528 KGVAFCHGRG 557 +G+AF H G Sbjct: 111 QGLAFIHKHG 120
>MK07_MOUSE (Q9WVS8) Mitogen-activated protein kinase 7 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 5) (ERK-5) (BMK1 kinase) Length = 806 Score = 59.7 bits (143), Expect = 5e-09 Identities = 38/127 (29%), Positives = 66/127 (51%), Gaps = 1/127 (0%) Frame = +3 Query: 171 DLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQD 350 D YE +E +G G YG V AR + TG+ VA+KK D LRE+ +L+ D Sbjct: 53 DEYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHD 112 Query: 351 PHVVRLLDLKQGQNKEGQ-TILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 +++ + D+ + G+ +Y+V + M++DL + I + Q + V+ +YQL Sbjct: 113 -NIIAIKDILKPTVPYGEFRSVYVVLDLMESDLHQII----HSSQPLTLEHVRYFLYQLL 167 Query: 528 KGVAFCH 548 +G+ + H Sbjct: 168 RGLKYMH 174
>CDKL3_MOUSE (Q8BLF2) Cyclin-dependent kinase-like 3 (EC 2.7.11.22)| Length = 595 Score = 59.7 bits (143), Expect = 5e-09 Identities = 38/131 (29%), Positives = 73/131 (55%), Gaps = 4/131 (3%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 M++YE L KVGEG+YG V K + K TGRIVA+ K + ++ V A RE+ L+ Sbjct: 1 MEMYETLGKVGEGSYGTVMKCKHKDTGRIVAI-KIFYEKPEKSVNKIATREIKFLKQFRH 59 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMD----TDLKKFIRGHRQNHQKIPAHTVKILM 515 + ++V L+++ + + K ++LVFE++D +L+ + G + + ++ + Sbjct: 60 E-NLVNLIEVFRQKKK-----IHLVFEFIDHTVLDELQHYCHG-------LESKRLRKYL 106 Query: 516 YQLCKGVAFCH 548 +Q+ + + + H Sbjct: 107 FQILRAIEYLH 117
>BUR1_CANGA (Q6FQ83) Serine/threonine-protein kinase BUR1 (EC 2.7.11.22) (EC| 2.7.11.23) Length = 667 Score = 59.7 bits (143), Expect = 5e-09 Identities = 39/144 (27%), Positives = 75/144 (52%), Gaps = 20/144 (13%) Frame = +3 Query: 177 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 356 Y++ EK+G+GT+G+VYK T R VA+K+ + ++++ P TA RE+++L+ L+ + Sbjct: 60 YKEEEKLGQGTFGEVYKGLHLQTQRKVAMKRIIVNQENDLFPITAQREITILKRLNH-KN 118 Query: 357 VVRLLDL-----KQGQNKE---------------GQTILYLVFEYMDTDLKKFIRGHRQN 476 +++LL++ + NK+ + Y++ YM DL + R Sbjct: 119 IIKLLEMVYDFPPESNNKDYAQFNQNNSANPPAVPKKFFYMILPYMVADLSGILHNPR-- 176 Query: 477 HQKIPAHTVKILMYQLCKGVAFCH 548 ++ +K +M Q+ +GV F H Sbjct: 177 -IELKMADIKNMMKQILEGVNFIH 199
>MK07_HUMAN (Q13164) Mitogen-activated protein kinase 7 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 5) (ERK-5) (ERK4) (BMK1 kinase) Length = 815 Score = 59.7 bits (143), Expect = 5e-09 Identities = 38/127 (29%), Positives = 66/127 (51%), Gaps = 1/127 (0%) Frame = +3 Query: 171 DLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQD 350 D YE +E +G G YG V AR + TG+ VA+KK D LRE+ +L+ D Sbjct: 52 DEYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHD 111 Query: 351 PHVVRLLDLKQGQNKEGQ-TILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 +++ + D+ + G+ +Y+V + M++DL + I + Q + V+ +YQL Sbjct: 112 -NIIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQII----HSSQPLTLEHVRYFLYQLL 166 Query: 528 KGVAFCH 548 +G+ + H Sbjct: 167 RGLKYMH 173
>MAK_HUMAN (P20794) Serine/threonine-protein kinase MAK (EC 2.7.11.22) (Male| germ cell-associated kinase) Length = 623 Score = 59.7 bits (143), Expect = 5e-09 Identities = 39/132 (29%), Positives = 72/132 (54%), Gaps = 2/132 (1%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALK--KTRLPEDDEGVPPTALREVSLLRML 341 M+ Y + ++G+GTYG V + +G +VA+K K + DE + LREV L+ L Sbjct: 1 MNRYTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECM---NLREVKSLKKL 57 Query: 342 SQDPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQ 521 + +V++L ++ + + LY +FEYM +L + + + ++ P ++ +MYQ Sbjct: 58 NH-ANVIKLKEVIRENDH-----LYFIFEYMKENLYQLM---KDRNKLFPESVIRNIMYQ 108 Query: 522 LCKGVAFCHGRG 557 + +G+AF H G Sbjct: 109 ILQGLAFIHKHG 120
>CDKL3_RAT (Q9JM01) Cyclin-dependent kinase-like 3 (EC 2.7.11.22)| (Serine/threonine protein kinase NKIATRE) Length = 593 Score = 59.7 bits (143), Expect = 5e-09 Identities = 38/131 (29%), Positives = 73/131 (55%), Gaps = 4/131 (3%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 M++YE L KVGEG+YG V K + K TGRIVA+ K + ++ V A RE+ L+ Sbjct: 1 MEMYETLGKVGEGSYGTVMKCKHKDTGRIVAI-KIFYEKPEKSVNKIATREIKFLKQFRH 59 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMD----TDLKKFIRGHRQNHQKIPAHTVKILM 515 + ++V L+++ + + K ++LVFE++D +L+ + G + + ++ + Sbjct: 60 E-NLVNLIEVFRQKKK-----IHLVFEFIDHTVLDELQHYCHG-------LESKRLRKYL 106 Query: 516 YQLCKGVAFCH 548 +Q+ + + + H Sbjct: 107 FQILRAIEYLH 117
>PRK1_SCHPO (O13958) Serine/threonine-protein kinase prk1 (EC 2.7.11.22)| (Suppressor of RNA polymerase B srb10) Length = 352 Score = 59.7 bits (143), Expect = 5e-09 Identities = 43/136 (31%), Positives = 70/136 (51%), Gaps = 10/136 (7%) Frame = +3 Query: 171 DLYEKLEKVGEGTYGKVYKAREKATG--RIVALKKTRLPE-------DDEGVPPTALREV 323 D Y+ + + GTYGKVYKA + R+ A+KK + GV +A+RE+ Sbjct: 3 DGYKIIGFISSGTYGKVYKAVSSNSNDKRLFAIKKFKAESKQVSSNAQQTGVSQSAIREM 62 Query: 324 SLLRMLSQDPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGH-RQNHQKIPAHT 500 L R + + ++ L Q K+G + +VFEY + DL + I H R ++IP Sbjct: 63 MLCREIQHE----NIVSLVQVLLKDG--TISMVFEYAEHDLLQIIHFHSRSRTRQIPPSI 116 Query: 501 VKILMYQLCKGVAFCH 548 +K +++Q+ GVA+ H Sbjct: 117 LKSILWQIINGVAYLH 132
>MAK_RAT (P20793) Serine/threonine-protein kinase MAK (EC 2.7.11.22) (Male| germ cell-associated kinase) Length = 622 Score = 59.7 bits (143), Expect = 5e-09 Identities = 39/132 (29%), Positives = 72/132 (54%), Gaps = 2/132 (1%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALK--KTRLPEDDEGVPPTALREVSLLRML 341 M+ Y + ++G+GTYG V + +G +VA+K K + DE + LREV L+ L Sbjct: 1 MNRYTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECM---NLREVKSLKKL 57 Query: 342 SQDPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQ 521 + +V++L ++ + + LY +FEYM +L + + + ++ P ++ +MYQ Sbjct: 58 NH-ANVIKLKEVIRENDH-----LYFIFEYMKENLYQLM---KDRNKLFPESVIRNIMYQ 108 Query: 522 LCKGVAFCHGRG 557 + +G+AF H G Sbjct: 109 ILQGLAFIHKHG 120
>MMK1_MEDSA (Q07176) Mitogen-activated protein kinase homolog MMK1 (EC| 2.7.11.24) (MAP kinase MSK7) (MAP kinase ERK1) Length = 387 Score = 59.3 bits (142), Expect = 7e-09 Identities = 36/118 (30%), Positives = 61/118 (51%) Frame = +3 Query: 195 VGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPHVVRLLD 374 +G+G YG V A T VA+KK D++ LRE+ LLR + + +VV + D Sbjct: 61 IGKGAYGIVCSAHNSETNEHVAVKKIANAFDNKIDAKRTLREIKLLRHMDHE-NVVAIRD 119 Query: 375 LKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLCKGVAFCH 548 + +E +Y+ +E MDTDL + IR ++Q + + +YQ+ +G+ + H Sbjct: 120 IVPPPQREVFNDVYIAYELMDTDLHQIIR----SNQALSEEHCQYFLYQILRGLKYIH 173
>CDKL3_HUMAN (Q8IVW4) Cyclin-dependent kinase-like 3 (EC 2.7.11.22)| (Serine/threonine protein kinase NKIAMRE) Length = 592 Score = 58.9 bits (141), Expect = 9e-09 Identities = 37/131 (28%), Positives = 73/131 (55%), Gaps = 4/131 (3%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 M++YE L KVGEG+YG V K + K TG+IVA+ K ++ V A+RE+ L+ Sbjct: 1 MEMYETLGKVGEGSYGTVMKCKHKNTGQIVAI-KIFYERPEQSVNKIAMREIKFLKQFHH 59 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMD----TDLKKFIRGHRQNHQKIPAHTVKILM 515 + ++V L+++ + + K ++LVFE++D +L+ + G + + ++ + Sbjct: 60 E-NLVNLIEVFRQKKK-----IHLVFEFIDHTVLDELQHYCHG-------LESKRLRKYL 106 Query: 516 YQLCKGVAFCH 548 +Q+ + + + H Sbjct: 107 FQILRAIDYLH 117
>SGG_DROME (P18431) Protein kinase shaggy (EC 2.7.11.1) (Protein zeste-white| 3) Length = 1067 Score = 58.9 bits (141), Expect = 9e-09 Identities = 36/127 (28%), Positives = 61/127 (48%) Frame = +3 Query: 177 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 356 Y + +G G++G V++A+ TG +VA+KK + RE+ ++R L Sbjct: 607 YTDTKVIGNGSFGVVFQAKLCDTGELVAIKKVLQDRRFKN------RELQIMRKLEHCNI 660 Query: 357 VVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLCKGV 536 V L K + L LV EY+ + K R + + Q IP + +++ MYQL + + Sbjct: 661 VKLLYFFYSSGEKRDEVFLNLVLEYIPETVYKVARQYAKTKQTIPINFIRLYMYQLFRSL 720 Query: 537 AFCHGRG 557 A+ H G Sbjct: 721 AYIHSLG 727
>MSK2_MEDSA (P51138) Glycogen synthase kinase-3 homolog MsK-2 (EC 2.7.11.1)| Length = 411 Score = 58.9 bits (141), Expect = 9e-09 Identities = 35/118 (29%), Positives = 65/118 (55%) Frame = +3 Query: 195 VGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPHVVRLLD 374 VG+G++G V++A+ TG VA+KK + + RE+ +R+L P+VV L Sbjct: 80 VGQGSFGVVFQAKCLETGETVAIKKVLQDKRYKN------RELQTMRLLDH-PNVVTLKH 132 Query: 375 LKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLCKGVAFCH 548 ++ + L LV E++ + + IR + + +Q++P VK+ YQ+C+ +A+ H Sbjct: 133 CFFSTTEKDELYLNLVLEFVPETVHRVIRHYSKMNQRMPLIYVKLYSYQICRSLAYIH 190
>BUR1_YEAST (P23293) Serine/threonine-protein kinase BUR1 (EC 2.7.11.22) (EC| 2.7.11.23) (Suppressor of GPA1-Vall50 mutation protein 1) (Bypass UAS requirement protein 1) Length = 657 Score = 58.9 bits (141), Expect = 9e-09 Identities = 37/132 (28%), Positives = 68/132 (51%), Gaps = 8/132 (6%) Frame = +3 Query: 177 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 356 Y + EK+G+GT+G+VYK T R VA+KK + + + P TA RE+++L+ L+ + Sbjct: 60 YREDEKLGQGTFGEVYKGIHLETQRQVAMKKIIVSVEKDLFPITAQREITILKRLNH-KN 118 Query: 357 VVRLL--------DLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKIL 512 +++L+ D+ + Y++ YM DL + R N + +K + Sbjct: 119 IIKLIEMVYDHSPDITNAASSNLHKSFYMILPYMVADLSGVLHNPRIN---LEMCDIKNM 175 Query: 513 MYQLCKGVAFCH 548 M Q+ +G+ + H Sbjct: 176 MLQILEGLNYIH 187
>NTF4_TOBAC (Q40532) Mitogen-activated protein kinase homolog NTF4 (EC| 2.7.11.24) (P45) Length = 393 Score = 58.9 bits (141), Expect = 9e-09 Identities = 35/118 (29%), Positives = 61/118 (51%) Frame = +3 Query: 195 VGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPHVVRLLD 374 +G+G YG V A T VA+KK D++ LRE+ LLR + + ++V + D Sbjct: 66 IGKGAYGIVCSALNSETNEHVAIKKIANAFDNKIDAKRTLREIKLLRHMDHE-NIVAIRD 124 Query: 375 LKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLCKGVAFCH 548 + +E +Y+ +E MDTDL + IR ++Q + + +YQ+ +G+ + H Sbjct: 125 IIPPPQREAFNDVYIAYELMDTDLHQIIR----SNQGLSEEHCQYFLYQILRGLKYIH 178
>MK13_PANTR (Q9N272) Mitogen-activated protein kinase 13 (EC 2.7.11.24)| (Stress-activated protein kinase 4) Length = 365 Score = 58.9 bits (141), Expect = 9e-09 Identities = 40/122 (32%), Positives = 60/122 (49%), Gaps = 1/122 (0%) Frame = +3 Query: 195 VGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPHVVRLLD 374 VG G YG V A +K +G VA+KK P E A RE+ LL+ + Q +V+ LLD Sbjct: 31 VGSGAYGSVCSAIDKRSGEKVAIKKLSRPFQSEIFAKRAYRELLLLKHM-QHENVIGLLD 89 Query: 375 L-KQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLCKGVAFCHG 551 + + YLV +M TDL+K + + ++ L+YQ+ KG+ + H Sbjct: 90 VFTPASSLRNFHDFYLVMXFMQTDLQKIM------XMEFSEEKIQYLVYQMLKGLKYIHS 143 Query: 552 RG 557 G Sbjct: 144 AG 145
>CDKL3_MACFA (Q4R8T9) Cyclin-dependent kinase-like 3 (EC 2.7.11.22)| Length = 590 Score = 58.9 bits (141), Expect = 9e-09 Identities = 37/131 (28%), Positives = 73/131 (55%), Gaps = 4/131 (3%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 M++YE L KVGEG+YG V K + K TG+IVA+ K ++ V A+RE+ L+ Sbjct: 1 MEMYETLGKVGEGSYGTVMKCKHKNTGQIVAI-KIFYERPEQSVNKIAMREIKFLKQFHH 59 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMD----TDLKKFIRGHRQNHQKIPAHTVKILM 515 + ++V L+++ + + K ++LVFE++D +L+ + G + + ++ + Sbjct: 60 E-NLVNLIEVFRQKKK-----IHLVFEFIDHTVLDELQHYCHG-------LESKRLRKYL 106 Query: 516 YQLCKGVAFCH 548 +Q+ + + + H Sbjct: 107 FQILRAIDYLH 117
>KSG5_ARATH (Q8VZD5) Shaggy-related protein kinase epsilon (EC 2.7.11.1)| (ASK-epsilon) Length = 410 Score = 58.5 bits (140), Expect = 1e-08 Identities = 35/119 (29%), Positives = 65/119 (54%) Frame = +3 Query: 195 VGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPHVVRLLD 374 VG+G++G V++A+ TG VA+KK + + RE+ +R+L P+VV L Sbjct: 80 VGQGSFGIVFQAKCLETGETVAIKKVLQDKRYKN------RELQTMRLLDH-PNVVSLKH 132 Query: 375 LKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLCKGVAFCHG 551 ++ + L LV EY+ + + + + + +Q++P VK+ YQ+C+ +A+ HG Sbjct: 133 CFFSTTEKDELYLNLVLEYVPETVYRVSKHYSRANQRMPIIYVKLYTYQICRALAYIHG 191
>MPK7_ARATH (Q39027) Mitogen-activated protein kinase homolog 7 (EC 2.7.11.24)| (MAP kinase 7) (AtMPK7) Length = 368 Score = 58.5 bits (140), Expect = 1e-08 Identities = 37/124 (29%), Positives = 63/124 (50%) Frame = +3 Query: 177 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 356 Y ++ +G G YG V + + T VA+KK ++ LRE+ LLR + + + Sbjct: 32 YVPIKPIGRGAYGVVCSSINRETNERVAIKKIHNVFENRVDALRTLRELKLLRHVRHE-N 90 Query: 357 VVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLCKGV 536 V+ L D+ N+ +YLV+E MDTDL + I+ + Q + K ++QL +G+ Sbjct: 91 VIALKDVMLPANRSSFKDVYLVYELMDTDLHQIIK----SSQSLSDDHCKYFLFQLLRGL 146 Query: 537 AFCH 548 + H Sbjct: 147 KYLH 150
>MAPK_PEA (Q06060) Mitogen-activated protein kinase homolog D5 (EC 2.7.11.24)| Length = 394 Score = 58.2 bits (139), Expect = 2e-08 Identities = 35/118 (29%), Positives = 61/118 (51%) Frame = +3 Query: 195 VGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPHVVRLLD 374 +G+G YG V A T VA+KK D++ LRE+ L+R + + +VV + D Sbjct: 68 IGKGAYGIVCSAHNSETNEHVAVKKIANAFDNKIDAKRTLREIKLVRHMDHE-NVVAIRD 126 Query: 375 LKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLCKGVAFCH 548 + +E +Y+ +E MDTDL + IR ++Q + + +YQ+ +G+ + H Sbjct: 127 IVPPPQREVFNDVYIAYELMDTDLHQIIR----SNQALSEEHCQYFLYQILRGLKYIH 180
>MAPK_FUSSO (Q00859) Mitogen-activated protein kinase (EC 2.7.11.24) (FsMAPK)| Length = 355 Score = 58.2 bits (139), Expect = 2e-08 Identities = 36/109 (33%), Positives = 58/109 (53%) Frame = +3 Query: 135 PMXXXXXXLRAMDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTAL 314 P + Y+ + VGEG YG V A K +G+ VA+KK P D L Sbjct: 9 PTGSRKISFNVSEQYDIQDVVGEGAYGVVCSAIHKPSGQKVAIKKI-TPFDHSMFCLRTL 67 Query: 315 REVSLLRMLSQDPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIR 461 RE+ LLR + + +++ +LD+++ +N E +YL+ E M+TD+ + IR Sbjct: 68 REMKLLRYFNHE-NIISILDIQKPRNYESFNEVYLIQELMETDMHRAIR 115
>KSG7_ARATH (Q39011) Shaggy-related protein kinase eta (EC 2.7.11.1) (ASK-eta)| (BRASSINOSTEROID-INSENSITIVE 2) (ULTRACURVATA1) Length = 380 Score = 57.8 bits (138), Expect = 2e-08 Identities = 36/118 (30%), Positives = 63/118 (53%) Frame = +3 Query: 195 VGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPHVVRLLD 374 VG G++G V++A+ TG VA+KK + RE+ L+R++ P+VV L Sbjct: 46 VGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMRVMDH-PNVVCLKH 98 Query: 375 LKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLCKGVAFCH 548 + + L LV EY+ L + ++ + +Q++P VK+ MYQ+ +G+A+ H Sbjct: 99 CFFSTTSKDELFLNLVMEYVPESLYRVLKHYSSANQRMPLVYVKLYMYQIFRGLAYIH 156
>MOK_MOUSE (Q9WVS4) MAPK/MAK/MRK overlapping kinase (EC 2.7.11.22) (MOK| protein kinase) Length = 420 Score = 57.8 bits (138), Expect = 2e-08 Identities = 43/135 (31%), Positives = 65/135 (48%), Gaps = 5/135 (3%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLP-EDDEGVPPTALREVSLLRMLS 344 M Y+ + K+GEGT+ +V K + G A K+ + E E V +LRE+ LR L+ Sbjct: 1 MKNYKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQHFESIEQV--NSLREIQALRRLN 58 Query: 345 QDPHVVRL----LDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKIL 512 P+++ L D K G L L+ E MD ++ + IRG R + + + Sbjct: 59 PHPNILALHEVVFDRKSGS-------LALICELMDMNIYELIRGRR---HPLSEKKIMLY 108 Query: 513 MYQLCKGVAFCHGRG 557 MYQLCK + H G Sbjct: 109 MYQLCKSLDHMHRNG 123
>MMK2_MEDSA (Q40353) Mitogen-activated protein kinase homolog MMK2 (EC| 2.7.11.24) Length = 371 Score = 57.8 bits (138), Expect = 2e-08 Identities = 39/121 (32%), Positives = 61/121 (50%) Frame = +3 Query: 186 LEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPHVVR 365 + VG G YG V A T VA+KK D+ LRE+ LLR + + +V+ Sbjct: 40 IRSVGRGAYGIVCAAVNAETREEVAIKKIGNAFDNRIDAKRTLREIKLLRHMDHE-NVMS 98 Query: 366 LLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLCKGVAFC 545 + D+ + KE +Y+V E MDTDL + IR ++Q + + +YQL +G+ + Sbjct: 99 IKDIIRPPQKENFNHVYIVSELMDTDLHQIIR----SNQPMTDDHCRYFVYQLLRGLKYV 154 Query: 546 H 548 H Sbjct: 155 H 155
>KSG6_ARATH (Q39010) Shaggy-related protein kinase dzeta (EC 2.7.11.1)| (ASK-dzeta) Length = 412 Score = 57.8 bits (138), Expect = 2e-08 Identities = 45/180 (25%), Positives = 80/180 (44%), Gaps = 1/180 (0%) Frame = +3 Query: 12 PQPPP-HQITRLARQPTREREREKARICATATLQHQNQGAAAPMXXXXXXLRAMDLYEKL 188 PQPP H L R+P + ++E + + + + Y Sbjct: 16 PQPPHLHGGDSLKRRPDIDNDKEMSAAVIEGNDAVTGHIISTTIGGKNGEPKQTISYMAE 75 Query: 189 EKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPHVVRL 368 VG G++G V++A+ TG VA+KK + RE+ L+R++ P+VV L Sbjct: 76 RVVGTGSFGIVFQAKCLETGESVAIKKVLQDRRYKN------RELQLMRLMDH-PNVVSL 128 Query: 369 LDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLCKGVAFCH 548 + L LV EY+ L + ++ + ++Q++P VK+ YQ+ +G+A+ H Sbjct: 129 KHCFFSTTTRDELFLNLVMEYVPETLYRVLKHYTSSNQRMPIFYVKLYTYQIFRGLAYIH 188
>ERK1_DICDI (P42525) Extracellular signal-regulated kinase 1 (EC 2.7.11.24)| (ERK1) (MAP kinase 1) Length = 415 Score = 57.8 bits (138), Expect = 2e-08 Identities = 37/124 (29%), Positives = 63/124 (50%) Frame = +3 Query: 177 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 356 Y ++ +G G YG V A++ TG VA+KK D+ LRE+ LLR + + Sbjct: 31 YSIVKCIGHGAYGVVCSAKDNLTGEKVAIKKISKAFDNLKDTKRTLREIHLLRHFKHE-N 89 Query: 357 VVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLCKGV 536 ++ + D+ + +KE +Y+V E MDTDL + I + Q + + +YQ+ +G+ Sbjct: 90 LISIKDILKPNSKEQFEDVYIVSELMDTDLHQII----TSPQPLSDDHCQYFVYQMLRGL 145 Query: 537 AFCH 548 H Sbjct: 146 KHIH 149
>NTF6_TOBAC (Q40531) Mitogen-activated protein kinase homolog NTF6 (EC| 2.7.11.24) (P43) Length = 371 Score = 57.4 bits (137), Expect = 3e-08 Identities = 35/121 (28%), Positives = 63/121 (52%) Frame = +3 Query: 186 LEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPHVVR 365 ++ VG G YG V A T VA+KK ++ LRE+ LL + + ++++ Sbjct: 41 IQPVGRGAYGMVCCATNSETKEEVAIKKIGNAFENRIDAKRTLREIKLLSHMDHE-NIIK 99 Query: 366 LLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLCKGVAFC 545 + D+ + ++E +Y+V+E MDTDL + IR + Q + + +YQL +G+ + Sbjct: 100 IKDIVRPPDREEFNDVYIVYELMDTDLHQIIR----SSQALTDDHCQYFLYQLLRGLKYV 155 Query: 546 H 548 H Sbjct: 156 H 156
>MPK2_ARATH (Q39022) Mitogen-activated protein kinase homolog 2 (EC 2.7.11.24)| (MAP kinase 2) (AtMPK2) Length = 376 Score = 57.0 bits (136), Expect = 4e-08 Identities = 37/124 (29%), Positives = 63/124 (50%) Frame = +3 Query: 177 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 356 Y ++ +G G YG V + + + VA+KK ++ LRE+ LLR L + + Sbjct: 32 YVPIKPIGRGAYGVVCSSVNRESNERVAIKKIHNVFENRIDALRTLRELKLLRHLRHE-N 90 Query: 357 VVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLCKGV 536 VV L D+ +K +YLV+E MDTDL + I+ + Q + + ++QL +G+ Sbjct: 91 VVALKDVMMANHKRSFKDVYLVYELMDTDLHQIIK----SSQVLSNDHCQYFLFQLLRGL 146 Query: 537 AFCH 548 + H Sbjct: 147 KYIH 150
>MPK6_ARATH (Q39026) Mitogen-activated protein kinase homolog 6 (EC 2.7.11.24)| (MAP kinase 6) (AtMPK6) Length = 395 Score = 57.0 bits (136), Expect = 4e-08 Identities = 34/118 (28%), Positives = 60/118 (50%) Frame = +3 Query: 195 VGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPHVVRLLD 374 +G+G YG V A T VA+KK D++ LRE+ LLR + + ++V + D Sbjct: 69 IGKGAYGIVCSAMNSETNESVAIKKIANAFDNKIDAKRTLREIKLLRHMDHE-NIVAIRD 127 Query: 375 LKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLCKGVAFCH 548 + + +Y+ +E MDTDL + IR ++Q + + +YQ+ +G+ + H Sbjct: 128 IIPPPLRNAFNDVYIAYELMDTDLHQIIR----SNQALSEEHCQYFLYQILRGLKYIH 181
>PIT1_SCHPO (O14132) Sporulation protein kinase pit1 (EC 2.7.11.1)| Length = 650 Score = 56.6 bits (135), Expect = 5e-08 Identities = 38/129 (29%), Positives = 66/129 (51%) Frame = +3 Query: 171 DLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQD 350 ++Y + KVG+GT+G VY A K + V K+ + + T LREV L LS++ Sbjct: 34 EVYNVVRKVGDGTFGSVYLATTKTPSKEVVAIKSMKKKLAKVSDATRLREVHSLLRLSEN 93 Query: 351 PHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLCK 530 ++V + DL Q + L++V E++D +L + I + + + V+ +M Q+ K Sbjct: 94 ENIVNIFDLYIDQFR----CLHIVMEFLDCNLYQLI--STRKNDPLTLEQVQDIMRQIFK 147 Query: 531 GVAFCHGRG 557 G+ H G Sbjct: 148 GLNHIHTNG 156
>KSG9_ARATH (Q39012) Shaggy-related protein kinase iota (EC 2.7.11.1)| (ASK-iota) Length = 407 Score = 56.6 bits (135), Expect = 5e-08 Identities = 35/118 (29%), Positives = 61/118 (51%) Frame = +3 Query: 195 VGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPHVVRLLD 374 VG G++G V++A+ TG VA+KK + RE+ L+R + P+V+ L Sbjct: 76 VGTGSFGIVFQAKCLETGESVAIKKVLQDRRYKN------RELQLMRPMDH-PNVISLKH 128 Query: 375 LKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLCKGVAFCH 548 + L LV EY+ L + +R + ++Q++P VK+ YQ+ +G+A+ H Sbjct: 129 CFFSTTSRDELFLNLVMEYVPETLYRVLRHYTSSNQRMPIFYVKLYTYQIFRGLAYIH 186
>NUAK1_HUMAN (O60285) NUAK family, SNF1-like kinase 1 (EC 2.7.11.1)| (AMPK-related protein kinase 5) Length = 661 Score = 56.6 bits (135), Expect = 5e-08 Identities = 37/129 (28%), Positives = 68/129 (52%), Gaps = 2/129 (1%) Frame = +3 Query: 177 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPE-DDEGVPPTALREVSLLRMLSQDP 353 YE E +G+GTYGKV +A E+ +GR+VA+K R + DE RE+ ++ L+ P Sbjct: 55 YELQETLGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDEQDMVHIRREIEIMSSLNH-P 113 Query: 354 HVVRLLDLKQGQNKEGQTILYLVFEYMDT-DLKKFIRGHRQNHQKIPAHTVKILMYQLCK 530 H++ + ++ + ++K + ++ EY +L +I R+ ++ H + Q+ Sbjct: 114 HIISIYEVFENKDK-----IVIIMEYASKGELYDYISERRRLSERETRHFFR----QIVS 164 Query: 531 GVAFCHGRG 557 V +CH G Sbjct: 165 AVHYCHKNG 173
>BUR1_ASHGO (Q75D46) Serine/threonine-protein kinase BUR1 (EC 2.7.11.22) (EC| 2.7.11.23) Length = 753 Score = 56.2 bits (134), Expect = 6e-08 Identities = 36/142 (25%), Positives = 72/142 (50%), Gaps = 18/142 (12%) Frame = +3 Query: 177 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 356 Y++ +K+G+GT+G+VY+ AT R VA+KK + +++ P TA RE+++L+ L+ + Sbjct: 56 YKEEKKLGQGTFGEVYRGVHLATQRQVAMKKILVKTENDLFPITAQREITILKRLNH-RN 114 Query: 357 VVRLLDL------------------KQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQ 482 VV+L+++ + + + Y++ YM DL + R Sbjct: 115 VVQLIEMVYDYPPAQNGAAYGQDSSQASASADTMKSFYMILPYMVADLSGILHNPRVT-- 172 Query: 483 KIPAHTVKILMYQLCKGVAFCH 548 + +K +M Q+ +G+ + H Sbjct: 173 -LEMADIKNMMLQILEGINYIH 193
>CPK1_CRYNE (Q8NK05) Mitogen-activated protein kinase CPK1 (EC 2.7.11.24)| (Stress-activated protein kinase CPK1) Length = 366 Score = 55.8 bits (133), Expect = 8e-08 Identities = 41/124 (33%), Positives = 62/124 (50%) Frame = +3 Query: 177 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 356 Y+ E VGEG YG V +G VA+K+ P D LRE+ LLR + + Sbjct: 16 YKLEEIVGEGAYGLVVAGTHLPSGTQVAIKRIT-PFDHTMFCQRTLREIKLLRHFHHE-N 73 Query: 357 VVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLCKGV 536 ++ +LDL Q ++ E +YLV E M+TDL + IR Q++ + +YQ +G+ Sbjct: 74 IISILDLIQPESYEVFNEVYLVQELMETDLHRVIRS-----QELSDDHCQYFVYQTLRGL 128 Query: 537 AFCH 548 H Sbjct: 129 KALH 132
>NUAK1_MOUSE (Q641K5) NUAK family, SNF1-like kinase 1 (EC 2.7.11.1)| Length = 658 Score = 55.8 bits (133), Expect = 8e-08 Identities = 37/129 (28%), Positives = 68/129 (52%), Gaps = 2/129 (1%) Frame = +3 Query: 177 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPE-DDEGVPPTALREVSLLRMLSQDP 353 YE E +G+GTYGKV +A E+ +GR+VA+K R + DE RE+ ++ L+ P Sbjct: 56 YELQETLGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDELDMVHIRREIEIMSSLNH-P 114 Query: 354 HVVRLLDLKQGQNKEGQTILYLVFEYMDT-DLKKFIRGHRQNHQKIPAHTVKILMYQLCK 530 H++ + ++ + ++K + ++ EY +L +I R+ ++ H + Q+ Sbjct: 115 HIISIYEVFENKDK-----IVIIMEYASKGELYDYISERRRLSERETRHFFR----QIVS 165 Query: 531 GVAFCHGRG 557 V +CH G Sbjct: 166 AVHYCHKNG 174
>MHK_ARATH (P43294) Serine/threonine-protein kinase MHK (EC 2.7.11.22)| Length = 443 Score = 55.8 bits (133), Expect = 8e-08 Identities = 41/129 (31%), Positives = 69/129 (53%), Gaps = 2/129 (1%) Frame = +3 Query: 177 YEKLEKVGEGTYGKVYKAREKATGRIVALK--KTRLPEDDEGVPPTALREVSLLRMLSQD 350 Y+ LE++G+GT G VYKA T +VA+K K + +E V LREV LR L+ Sbjct: 12 YKILEELGDGTCGSVYKAVNLETYEVVAVKKMKRKFYYWEECV---NLREVKALRKLNH- 67 Query: 351 PHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLCK 530 PH+++L ++ + N+ L+ +FE MD +L + ++ + ++ M Q+ + Sbjct: 68 PHIIKLKEIVREHNE-----LFFIFECMDHNLYHIM---KERERPFSEGEIRSFMSQMLQ 119 Query: 531 GVAFCHGRG 557 G+A H G Sbjct: 120 GLAHMHKNG 128
>MOK_HUMAN (Q9UQ07) MAPK/MAK/MRK overlapping kinase (EC 2.7.11.22) (MOK| protein kinase) (Renal tumor antigen 1) (RAGE-1) Length = 419 Score = 55.5 bits (132), Expect = 1e-07 Identities = 46/137 (33%), Positives = 65/137 (47%), Gaps = 7/137 (5%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLP-EDDEGVPPTALREVSLLRMLS 344 M Y+ + K+GEGT+ +V K + G A K+ + E E V LRE+ LR L+ Sbjct: 1 MKNYKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQRFESIEQV--NNLREIQALRRLN 58 Query: 345 QDPHVVRL----LDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKIL 512 P+++ L D K G L L+ E MD ++ + IRG R P KI+ Sbjct: 59 PHPNILMLHEVVFDRKSGS-------LALICELMDMNIYELIRGRR-----YPLSEKKIM 106 Query: 513 --MYQLCKGVAFCHGRG 557 MYQLCK + H G Sbjct: 107 HYMYQLCKSLDHIHRNG 123
>NTF3_TOBAC (Q40517) Mitogen-activated protein kinase homolog NTF3 (EC| 2.7.11.24) (P43) Length = 372 Score = 55.5 bits (132), Expect = 1e-07 Identities = 36/124 (29%), Positives = 63/124 (50%) Frame = +3 Query: 177 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 356 Y ++ +G G YG V + + T VA+KK ++ LRE+ LLR L + + Sbjct: 32 YVPIKPIGRGAYGIVCSSVNRETNEKVAIKKINNAFENRIDALRTLRELKLLRHLRHE-N 90 Query: 357 VVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLCKGV 536 V+ L D+ ++ +YLV+E MDTDL + I+ + Q + + ++QL +G+ Sbjct: 91 VIALKDVMMPIHRRSFKDVYLVYELMDTDLHQIIK----SSQTLSNDHCQYFLFQLLRGL 146 Query: 537 AFCH 548 + H Sbjct: 147 KYLH 150
>MPK3_ARATH (Q39023) Mitogen-activated protein kinase homolog 3 (EC 2.7.11.24)| (MAP kinase 3) (AtMPK3) Length = 370 Score = 55.1 bits (131), Expect = 1e-07 Identities = 34/118 (28%), Positives = 59/118 (50%) Frame = +3 Query: 195 VGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPHVVRLLD 374 +G G YG V + T +VA+KK D+ LRE+ LLR L + +++ + D Sbjct: 44 IGRGAYGIVCSVLDTETNELVAMKKIANAFDNHMDAKRTLREIKLLRHLDHE-NIIAIRD 102 Query: 375 LKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLCKGVAFCH 548 + + + +Y+ E MDTDL + IR ++Q + + +YQL +G+ + H Sbjct: 103 VVPPPLRRQFSDVYISTELMDTDLHQIIR----SNQSLSEEHCQYFLYQLLRGLKYIH 156
>MAPK_PETHY (Q40884) Mitogen-activated protein kinase homolog 1 (EC 2.7.11.24)| (PMEK1) Length = 384 Score = 55.1 bits (131), Expect = 1e-07 Identities = 36/124 (29%), Positives = 62/124 (50%) Frame = +3 Query: 177 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 356 Y ++ +G G YG V + + T VA+KK ++ LRE+ LLR L + + Sbjct: 32 YVPIKPIGRGAYGIVCSSVNRETNEKVAIKKINNAFENRIDALRTLRELKLLRHLRHE-N 90 Query: 357 VVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLCKGV 536 V+ L D+ + +YLV+E MDTDL + I+ + Q + + ++QL +G+ Sbjct: 91 VIALKDVMMPIQRRSFKDVYLVYELMDTDLHQIIK----SSQTLSNDHCQYFLFQLLRGL 146 Query: 537 AFCH 548 + H Sbjct: 147 KYLH 150
>SNF1_CANAL (P52497) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 620 Score = 55.1 bits (131), Expect = 1e-07 Identities = 39/128 (30%), Positives = 67/128 (52%), Gaps = 4/128 (3%) Frame = +3 Query: 177 YEKLEKVGEGTYGKVYKAREKATGRIVALK----KTRLPEDDEGVPPTALREVSLLRMLS 344 Y+ L+ +GEG++GKV A+ TG+ VALK KT D +G RE+S LR+L Sbjct: 53 YQILKTLGEGSFGKVKLAQHLGTGQKVALKIINRKTLAKSDMQG---RVEREISYLRLL- 108 Query: 345 QDPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQL 524 + PH+++L D+ + +++ + +V E+ +L +I K+P + Q+ Sbjct: 109 RHPHIIKLYDVIKSKDE-----IIMVIEFAGKELFDYI----VQRGKMPEDEARRFFQQI 159 Query: 525 CKGVAFCH 548 V +CH Sbjct: 160 IAAVEYCH 167
>FUS3_YEAST (P16892) Mitogen-activated protein kinase FUS3 (EC 2.7.11.24) (MAP| kinase FUS3) Length = 353 Score = 55.1 bits (131), Expect = 1e-07 Identities = 35/119 (29%), Positives = 60/119 (50%) Frame = +3 Query: 195 VGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPHVVRLLD 374 +GEG YG V A K TG IVA+KK P D LRE+ +L+ + +++ + + Sbjct: 19 LGEGAYGVVCSATHKPTGEIVAIKKIE-PFDKPLFALRTLREIKILKHFKHE-NIITIFN 76 Query: 375 LKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLCKGVAFCHG 551 +++ + E +Y++ E M TDL + I + Q + ++ +YQ + V HG Sbjct: 77 IQRPDSFENFNEVYIIQELMQTDLHRVI-----STQMLSDDHIQYFIYQTLRAVKVLHG 130
>MPK1_ARATH (Q39021) Mitogen-activated protein kinase homolog 1 (EC 2.7.11.24)| (MAP kinase 1) (AtMPK1) Length = 370 Score = 54.7 bits (130), Expect = 2e-07 Identities = 37/124 (29%), Positives = 62/124 (50%) Frame = +3 Query: 177 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 356 Y ++ +G G YG V + T VA+KK ++ LRE+ LLR L + + Sbjct: 32 YMPIKPIGRGAYGVVCSSVNSDTNEKVAIKKIHNVYENRIDALRTLRELKLLRHLRHE-N 90 Query: 357 VVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLCKGV 536 V+ L D+ +K +YLV+E MDTDL + I+ + Q + + ++QL +G+ Sbjct: 91 VIALKDVMMPIHKMSFKDVYLVYELMDTDLHQIIK----SSQVLSNDHCQYFLFQLLRGL 146 Query: 537 AFCH 548 + H Sbjct: 147 KYIH 150
>MK14_RAT (P70618) Mitogen-activated protein kinase 14 (EC 2.7.11.24)| (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (CRK1) Length = 359 Score = 54.7 bits (130), Expect = 2e-07 Identities = 39/125 (31%), Positives = 61/125 (48%), Gaps = 1/125 (0%) Frame = +3 Query: 177 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 356 Y+ L VG G YG V A + TG VA+KK P RE+ LL+ + + + Sbjct: 23 YQNLSPVGSGAYGSVCAAFDTKTGHRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHE-N 81 Query: 357 VVRLLDL-KQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLCKG 533 V+ LLD+ ++ E +YLV M DL ++ QK+ V+ L+YQ+ +G Sbjct: 82 VIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVK-----CQKLTDDHVQFLIYQILRG 136 Query: 534 VAFCH 548 + + H Sbjct: 137 LKYIH 141
>MK14_MOUSE (P47811) Mitogen-activated protein kinase 14 (EC 2.7.11.24)| (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (CRK1) Length = 359 Score = 54.7 bits (130), Expect = 2e-07 Identities = 39/125 (31%), Positives = 61/125 (48%), Gaps = 1/125 (0%) Frame = +3 Query: 177 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 356 Y+ L VG G YG V A + TG VA+KK P RE+ LL+ + + + Sbjct: 23 YQNLSPVGSGAYGSVCAAFDTKTGHRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHE-N 81 Query: 357 VVRLLDL-KQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLCKG 533 V+ LLD+ ++ E +YLV M DL ++ QK+ V+ L+YQ+ +G Sbjct: 82 VIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVK-----CQKLTDDHVQFLIYQILRG 136 Query: 534 VAFCH 548 + + H Sbjct: 137 LKYIH 141
>STK4_HUMAN (Q13043) Serine/threonine-protein kinase 4 (EC 2.7.11.1)| (STE20-like kinase MST1) (MST-1) (Mammalian STE20-like protein kinase 1) (Serine/threonine-protein kinase Krs-2) Length = 487 Score = 54.7 bits (130), Expect = 2e-07 Identities = 37/126 (29%), Positives = 66/126 (52%) Frame = +3 Query: 171 DLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQD 350 ++++ LEK+GEG+YG VYKA K TG+IVA+K+ + D + + ++E+S+++ Sbjct: 28 EVFDVLEKLGEGSYGSVYKAIHKETGQIVAIKQVPVESDLQEI----IKEISIMQQ-CDS 82 Query: 351 PHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLCK 530 PHVV K + T L++V EY I R ++ + + ++ K Sbjct: 83 PHVV-----KYYGSYFKNTDLWIVMEYCGAGSVSDI--IRLRNKTLTEDEIATILQSTLK 135 Query: 531 GVAFCH 548 G+ + H Sbjct: 136 GLEYLH 141
>GSK3A_HUMAN (P49840) Glycogen synthase kinase-3 alpha (EC 2.7.11.26) (GSK-3| alpha) Length = 483 Score = 54.7 bits (130), Expect = 2e-07 Identities = 38/128 (29%), Positives = 64/128 (50%), Gaps = 1/128 (0%) Frame = +3 Query: 177 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 356 Y ++ +G G++G VY+AR T +VA+KK + + RE+ ++R L Sbjct: 119 YTDIKVIGNGSFGVVYQARLAETRELVAIKKVLQDKRFKN------RELQIMRKLDHCNI 172 Query: 357 V-VRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLCKG 533 V +R G+ K+ + L LV EY+ + + R + IP VK+ MYQL + Sbjct: 173 VRLRYFFYSSGEKKD-ELYLNLVLEYVPETVYRVARHFTKAKLTIPILYVKVYMYQLFRS 231 Query: 534 VAFCHGRG 557 +A+ H +G Sbjct: 232 LAYIHSQG 239
>PMK2_CAEEL (Q8MXI4) Mitogen-activated protein kinase pmk-2 (EC 2.7.11.24) (p38| MAP kinase 2) (Stress-activated protein kinase pmk-2) Length = 419 Score = 54.3 bits (129), Expect = 2e-07 Identities = 37/128 (28%), Positives = 63/128 (49%), Gaps = 1/128 (0%) Frame = +3 Query: 177 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 356 Y L+ +GEG YG V A + TG VA+KK P RE+ LLR L D + Sbjct: 49 YNSLKPLGEGAYGVVCTAEYEPTGDRVAIKKFFRPFQSTIHAKRTYRELKLLRTLQHD-N 107 Query: 357 VVRLLDL-KQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLCKG 533 V+ ++D+ + +Y V M +DL+ ++ Q++ +++L+YQ+ +G Sbjct: 108 VLEMIDVFTPDPDASSLNNVYFVSVLMGSDLQNIMK-----IQRLTDEQIQLLIYQVLRG 162 Query: 534 VAFCHGRG 557 + + H G Sbjct: 163 LKYIHSAG 170
>MK14A_CYPCA (Q90336) Mitogen-activated protein kinase 14a (EC 2.7.11.24)| (Mitogen-activated protein kinase p38a) (MAP kinase p38a) (cp38a) Length = 361 Score = 54.3 bits (129), Expect = 2e-07 Identities = 39/125 (31%), Positives = 61/125 (48%), Gaps = 1/125 (0%) Frame = +3 Query: 177 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 356 Y+ L VG G YG V A ++ TG VA+KK P RE+ LL+ + + + Sbjct: 25 YQNLSPVGSGAYGTVCSAYDEKTGLKVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHE-N 83 Query: 357 VVRLLDL-KQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLCKG 533 V+ LLD+ + E +YLV M DL ++ QK+ V+ L+YQ+ +G Sbjct: 84 VIGLLDVFTPATSLEEFNDVYLVTHLMGADLNNIVK-----CQKLTDDHVQFLIYQILRG 138 Query: 534 VAFCH 548 + + H Sbjct: 139 LKYIH 143
>NEK2_HUMAN (P51955) Serine/threonine-protein kinase Nek2 (EC 2.7.11.1)| (NimA-related protein kinase 2) (NimA-like protein kinase 1) (HSPK 21) Length = 445 Score = 54.3 bits (129), Expect = 2e-07 Identities = 44/132 (33%), Positives = 63/132 (47%), Gaps = 1/132 (0%) Frame = +3 Query: 162 RAMDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 341 RA D YE L +G G+YG+ K R K+ G+I+ K+ E + EV+LLR L Sbjct: 4 RAED-YEVLYTIGTGSYGRCQKIRRKSDGKILVWKELDYGSMTEAEKQMLVSEVNLLREL 62 Query: 342 SQDPHVVRLLDLKQGQNKEGQTILYLVFEYMD-TDLKKFIRGHRQNHQKIPAHTVKILMY 518 + P++VR D + T LY+V EY + DL I + Q + V +M Sbjct: 63 -KHPNIVRYYDRIIDRT---NTTLYIVMEYCEGGDLASVITKGTKERQYLDEEFVLRVMT 118 Query: 519 QLCKGVAFCHGR 554 QL + CH R Sbjct: 119 QLTLALKECHRR 130
>NEK2_MOUSE (O35942) Serine/threonine-protein kinase Nek2 (EC 2.7.11.1)| (NimA-related protein kinase 2) Length = 443 Score = 54.3 bits (129), Expect = 2e-07 Identities = 41/127 (32%), Positives = 61/127 (48%), Gaps = 1/127 (0%) Frame = +3 Query: 177 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 356 YE L +G G+YG+ K R K+ G+I+ K+ E + EV+LLR L + P+ Sbjct: 8 YEVLHSIGTGSYGRCQKIRRKSDGKILVWKELDYGSMTEVEKQMLVSEVNLLREL-KHPN 66 Query: 357 VVRLLDLKQGQNKEGQTILYLVFEYMD-TDLKKFIRGHRQNHQKIPAHTVKILMYQLCKG 533 +VR D + T LY+V EY + DL I ++ Q + V +M QL Sbjct: 67 IVRYYDRIIDRT---NTTLYIVMEYCEGGDLASVISKGTKDRQYLEEEFVLRVMTQLTLA 123 Query: 534 VAFCHGR 554 + CH R Sbjct: 124 LKECHRR 130
>SNF1_CANTR (O94168) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 619 Score = 54.3 bits (129), Expect = 2e-07 Identities = 38/128 (29%), Positives = 67/128 (52%), Gaps = 4/128 (3%) Frame = +3 Query: 177 YEKLEKVGEGTYGKVYKAREKATGRIVALK----KTRLPEDDEGVPPTALREVSLLRMLS 344 Y+ ++ +GEG++GKV A+ TG+ VALK KT D +G RE+S LR+L Sbjct: 52 YQIIKTLGEGSFGKVKLAQHVGTGQKVALKIINRKTLAKSDMQG---RVEREISYLRLL- 107 Query: 345 QDPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQL 524 + PH+++L D+ + +++ + +V E+ +L +I K+P + Q+ Sbjct: 108 RHPHIIKLYDVIKSKDE-----IIMVIEFAGKELFDYI----VQRGKMPEDEARRFFQQI 158 Query: 525 CKGVAFCH 548 V +CH Sbjct: 159 IAAVEYCH 166
>MSK1_TOBAC (Q40518) Shaggy-related protein kinase NtK-1 (EC 2.7.11.1)| Length = 409 Score = 53.9 bits (128), Expect = 3e-07 Identities = 33/118 (27%), Positives = 64/118 (54%) Frame = +3 Query: 195 VGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPHVVRLLD 374 VG+G++G V++A+ TG VA+KK + + RE+ +R+L P+VV L Sbjct: 79 VGQGSFGVVFQAKCLETGETVAIKKVLQDKRYKN------RELQTMRLLDH-PNVVCLKH 131 Query: 375 LKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLCKGVAFCH 548 ++ + L LV EY+ + + I+ + + +Q++P VK+ YQ+ + +++ H Sbjct: 132 CFFSTTEKDEVYLNLVLEYVPETVHRVIKHYNKLNQRMPLILVKLYTYQIFRALSYIH 189
>MK14_PANTR (Q95NE7) Mitogen-activated protein kinase 14 (EC 2.7.11.24)| (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (Stress-activated protein kinase 2a) Length = 359 Score = 53.9 bits (128), Expect = 3e-07 Identities = 39/125 (31%), Positives = 61/125 (48%), Gaps = 1/125 (0%) Frame = +3 Query: 177 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 356 Y+ L VG G YG V A + TG VA+KK P RE+ LL+ + + + Sbjct: 23 YQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHE-N 81 Query: 357 VVRLLDL-KQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLCKG 533 V+ LLD+ ++ E +YLV M DL ++ QK+ V+ L+YQ+ +G Sbjct: 82 VIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVK-----CQKLTDDHVQFLIYQILRG 136 Query: 534 VAFCH 548 + + H Sbjct: 137 LKYIH 141
>MK14_HUMAN (Q16539) Mitogen-activated protein kinase 14 (EC 2.7.11.24)| (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (Cytokine suppressive anti-inflammatory drug-binding protein) (CSAID-binding protein) (CSBP) (MAX-interacting prote Length = 359 Score = 53.9 bits (128), Expect = 3e-07 Identities = 39/125 (31%), Positives = 61/125 (48%), Gaps = 1/125 (0%) Frame = +3 Query: 177 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 356 Y+ L VG G YG V A + TG VA+KK P RE+ LL+ + + + Sbjct: 23 YQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHE-N 81 Query: 357 VVRLLDL-KQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLCKG 533 V+ LLD+ ++ E +YLV M DL ++ QK+ V+ L+YQ+ +G Sbjct: 82 VIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVK-----CQKLTDDHVQFLIYQILRG 136 Query: 534 VAFCH 548 + + H Sbjct: 137 LKYIH 141
>MK14_CANFA (O02812) Mitogen-activated protein kinase 14 (EC 2.7.11.24)| (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) Length = 359 Score = 53.9 bits (128), Expect = 3e-07 Identities = 39/125 (31%), Positives = 61/125 (48%), Gaps = 1/125 (0%) Frame = +3 Query: 177 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 356 Y+ L VG G YG V A + TG VA+KK P RE+ LL+ + + + Sbjct: 23 YQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHE-N 81 Query: 357 VVRLLDL-KQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLCKG 533 V+ LLD+ ++ E +YLV M DL ++ QK+ V+ L+YQ+ +G Sbjct: 82 VIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVK-----CQKLTDDHVQFLIYQILRG 136 Query: 534 VAFCH 548 + + H Sbjct: 137 LKYIH 141
>GSK3A_RAT (P18265) Glycogen synthase kinase-3 alpha (EC 2.7.11.26) (GSK-3| alpha) (Factor A) (FA) Length = 483 Score = 53.9 bits (128), Expect = 3e-07 Identities = 38/128 (29%), Positives = 64/128 (50%), Gaps = 1/128 (0%) Frame = +3 Query: 177 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 356 Y ++ +G G++G VY+AR T +VA+KK + + RE+ ++R L Sbjct: 119 YTDIKVIGNGSFGVVYQARLAETRELVAIKKVLQDKRFKN------RELQIMRKLDHCNI 172 Query: 357 V-VRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLCKG 533 V +R G+ K+ + L LV EY+ + + R + IP VK+ MYQL + Sbjct: 173 VRLRYFFYSSGEKKD-ELYLNLVLEYVPETVYRVARHFTKAKLIIPIIYVKVYMYQLFRS 231 Query: 534 VAFCHGRG 557 +A+ H +G Sbjct: 232 LAYIHSQG 239
>YPC2_CAEEL (Q11179) Putative serine/threonine-protein kinase C05D10.2 in| chromosome III (EC 2.7.11.24) Length = 470 Score = 53.5 bits (127), Expect = 4e-07 Identities = 37/128 (28%), Positives = 64/128 (50%), Gaps = 4/128 (3%) Frame = +3 Query: 177 YEKLEKVGEGTYGKVYKAREKATGRIVALKKT----RLPEDDEGVPPTALREVSLLRMLS 344 ++ +++G+G YG V+KA +K + VALKK R P D + REV L+ Sbjct: 13 FDLQKRLGKGAYGIVWKAYDKRSRETVALKKIFDAFRNPTDSQ----RTFREVMFLQEFG 68 Query: 345 QDPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQL 524 + P+V++L ++ + N +YL FE+M+ DL I+ + + +M QL Sbjct: 69 KHPNVIKLYNIFRADNDRD---IYLAFEFMEADLHNVIK----KGSILKDVHKQYIMCQL 121 Query: 525 CKGVAFCH 548 + + F H Sbjct: 122 FRAIRFLH 129
>GSK3B_RAT (P18266) Glycogen synthase kinase-3 beta (EC 2.7.11.26) (GSK-3| beta) (Factor A) (FA) Length = 420 Score = 53.5 bits (127), Expect = 4e-07 Identities = 36/128 (28%), Positives = 65/128 (50%), Gaps = 1/128 (0%) Frame = +3 Query: 177 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 356 Y + +G G++G VY+A+ +G +VA+KK + + RE+ ++R L Sbjct: 56 YTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKN------RELQIMRKLDHCNI 109 Query: 357 V-VRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLCKG 533 V +R G+ K+ + L LV +Y+ + + R + + Q +P VK+ MYQL + Sbjct: 110 VRLRYFFYSSGEKKD-EVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRS 168 Query: 534 VAFCHGRG 557 +A+ H G Sbjct: 169 LAYIHSFG 176
>GSK3B_MOUSE (Q9WV60) Glycogen synthase kinase-3 beta (EC 2.7.11.26) (GSK-3| beta) Length = 420 Score = 53.5 bits (127), Expect = 4e-07 Identities = 36/128 (28%), Positives = 65/128 (50%), Gaps = 1/128 (0%) Frame = +3 Query: 177 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 356 Y + +G G++G VY+A+ +G +VA+KK + + RE+ ++R L Sbjct: 56 YTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKN------RELQIMRKLDHCNI 109 Query: 357 V-VRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLCKG 533 V +R G+ K+ + L LV +Y+ + + R + + Q +P VK+ MYQL + Sbjct: 110 VRLRYFFYSSGEKKD-EVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRS 168 Query: 534 VAFCHGRG 557 +A+ H G Sbjct: 169 LAYIHSFG 176
>GSK3B_HUMAN (P49841) Glycogen synthase kinase-3 beta (EC 2.7.11.26) (GSK-3| beta) Length = 420 Score = 53.5 bits (127), Expect = 4e-07 Identities = 36/128 (28%), Positives = 65/128 (50%), Gaps = 1/128 (0%) Frame = +3 Query: 177 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 356 Y + +G G++G VY+A+ +G +VA+KK + + RE+ ++R L Sbjct: 56 YTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKN------RELQIMRKLDHCNI 109 Query: 357 V-VRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLCKG 533 V +R G+ K+ + L LV +Y+ + + R + + Q +P VK+ MYQL + Sbjct: 110 VRLRYFFYSSGEKKD-EVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRS 168 Query: 534 VAFCHGRG 557 +A+ H G Sbjct: 169 LAYIHSFG 176
>MK14_XENLA (P47812) Mitogen-activated protein kinase 14 (EC 2.7.11.24)| (Mitogen-activated Mitogen-activated protein kinase 2) (MAP kinase 2) (MPK2) Length = 361 Score = 53.5 bits (127), Expect = 4e-07 Identities = 38/130 (29%), Positives = 62/130 (47%), Gaps = 1/130 (0%) Frame = +3 Query: 171 DLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQD 350 D Y+ L VG G YG V + + T +A+KK P RE+ LL+ + + Sbjct: 23 DRYQNLTPVGSGAYGSVCSSFDTRTALRIAVKKLSRPFQSIIHAKRTYRELRLLKHMKHE 82 Query: 351 PHVVRLLDL-KQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 +V+ LLD+ ++ E +YLV M DL ++ QK+ V+ L+YQ+ Sbjct: 83 -NVIGLLDVFSPAKSFEEFNDVYLVTHLMGADLNNIVK-----CQKLTDDHVQFLIYQIL 136 Query: 528 KGVAFCHGRG 557 +G+ + H G Sbjct: 137 RGLKYIHSAG 146
>STK36_PONPY (Q5RAJ5) Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused| homolog) Length = 1315 Score = 53.5 bits (127), Expect = 4e-07 Identities = 36/127 (28%), Positives = 66/127 (51%) Frame = +3 Query: 168 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 347 M+ Y LE +GEG++G+VYK R K + ++VALK E RE+ ++R L + Sbjct: 1 MEKYHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGL-R 59 Query: 348 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLC 527 P++V +LD + E + +V +Y + +L + + ++ K+P V+ + QL Sbjct: 60 HPNIVHMLD-----SFETDKEVVVVTDYAEGELLQIL----EDDGKLPEDQVQAIAAQLV 110 Query: 528 KGVAFCH 548 + + H Sbjct: 111 SALYYLH 117
>GSK3H_DROME (P83101) Putative glycogen synthase kinase-3 homolog (EC 2.7.11.26)| (GSK-3) (Protein gasket) Length = 501 Score = 53.5 bits (127), Expect = 4e-07 Identities = 33/127 (25%), Positives = 59/127 (46%) Frame = +3 Query: 177 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 356 Y + VG G++G V++A+ + +VA+KK + RE+ ++R L D Sbjct: 33 YTDAKVVGNGSFGVVFQAKMVPSNEMVAIKKVLQDRRFKN------RELQIMRKLRHDNI 86 Query: 357 VVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLCKGV 536 + K + L LV E++ L K R + + Q +P + V++ MYQL + + Sbjct: 87 ITLKWFFFSSGEKRDEVYLNLVMEFLPETLYKVERQYARAKQTLPVNFVRLYMYQLLRSM 146 Query: 537 AFCHGRG 557 + H G Sbjct: 147 GYLHSLG 153
>NEK6_RAT (P59895) Serine/threonine-protein kinase Nek6 (EC 2.7.11.1)| (NimA-related protein kinase 6) Length = 313 Score = 53.1 bits (126), Expect = 5e-07 Identities = 39/124 (31%), Positives = 62/124 (50%), Gaps = 2/124 (1%) Frame = +3 Query: 189 EKVGEGTYGKVYKAREKATGRIVALKKTRLPE-DDEGVPPTALREVSLLRMLSQDPHVVR 365 +K+G G + +VYKA + VALKK ++ E D ++E+ LL+ L+ P++++ Sbjct: 49 KKIGRGQFSEVYKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQLNH-PNIIK 107 Query: 366 LLDLKQGQNKEGQTILYLVFEYMDT-DLKKFIRGHRQNHQKIPAHTVKILMYQLCKGVAF 542 LD N+ L +V E D DL + I+ ++ + IP TV QLC V Sbjct: 108 YLDSFIEDNE-----LNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEH 162 Query: 543 CHGR 554 H R Sbjct: 163 MHSR 166
>NEK6_MOUSE (Q9ES70) Serine/threonine-protein kinase Nek6 (EC 2.7.11.1)| (NimA-related protein kinase 6) Length = 313 Score = 53.1 bits (126), Expect = 5e-07 Identities = 39/124 (31%), Positives = 62/124 (50%), Gaps = 2/124 (1%) Frame = +3 Query: 189 EKVGEGTYGKVYKAREKATGRIVALKKTRLPE-DDEGVPPTALREVSLLRMLSQDPHVVR 365 +K+G G + +VYKA + VALKK ++ E D ++E+ LL+ L+ P++++ Sbjct: 49 KKIGRGQFSEVYKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQLNH-PNIIK 107 Query: 366 LLDLKQGQNKEGQTILYLVFEYMDT-DLKKFIRGHRQNHQKIPAHTVKILMYQLCKGVAF 542 LD N+ L +V E D DL + I+ ++ + IP TV QLC V Sbjct: 108 YLDSFIEDNE-----LNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEH 162 Query: 543 CHGR 554 H R Sbjct: 163 MHSR 166
>NEK6_HUMAN (Q9HC98) Serine/threonine-protein kinase Nek6 (EC 2.7.11.1)| (NimA-related protein kinase 6) (Protein kinase SID6-1512) Length = 313 Score = 53.1 bits (126), Expect = 5e-07 Identities = 39/124 (31%), Positives = 62/124 (50%), Gaps = 2/124 (1%) Frame = +3 Query: 189 EKVGEGTYGKVYKAREKATGRIVALKKTRLPE-DDEGVPPTALREVSLLRMLSQDPHVVR 365 +K+G G + +VYKA + VALKK ++ E D ++E+ LL+ L+ P++++ Sbjct: 49 KKIGRGQFSEVYKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQLNH-PNIIK 107 Query: 366 LLDLKQGQNKEGQTILYLVFEYMDT-DLKKFIRGHRQNHQKIPAHTVKILMYQLCKGVAF 542 LD N+ L +V E D DL + I+ ++ + IP TV QLC V Sbjct: 108 YLDSFIEDNE-----LNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEH 162 Query: 543 CHGR 554 H R Sbjct: 163 MHSR 166
>MK03_HUMAN (P27361) Mitogen-activated protein kinase 3 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 1) (ERK-1) (Insulin-stimulated MAP2 kinase) (MAP kinase 1) (MAPK 1) (p44-ERK1) (ERT2) (p44-MAPK) (Microtubule-associated protein 2 kinase) Length = 379 Score = 53.1 bits (126), Expect = 5e-07 Identities = 33/124 (26%), Positives = 62/124 (50%) Frame = +3 Query: 177 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 356 Y +L+ +GEG YG V A + VA+KK P + + LRE+ +L + + Sbjct: 42 YTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKIS-PFEHQTYCQRTLREIQILLRFRHE-N 99 Query: 357 VVRLLDLKQGQNKEGQTILYLVFEYMDTDLKKFIRGHRQNHQKIPAHTVKILMYQLCKGV 536 V+ + D+ + E +Y+V + M+TDL K ++ Q++ + +YQ+ +G+ Sbjct: 100 VIGIRDILRASTLEAMRDVYIVQDLMETDLYKLLKS-----QQLSNDHICYFLYQILRGL 154 Query: 537 AFCH 548 + H Sbjct: 155 KYIH 158 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.310 0.127 0.430 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 53,861,866 Number of Sequences: 219361 Number of extensions: 906642 Number of successful extensions: 5416 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 4483 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4978 length of database: 80,573,946 effective HSP length: 106 effective length of database: 57,321,680 effective search space used: 4528412720 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.7 bits)
