ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | bart26f11 |
|---|---|
| Clone Library Name | barley_pub |
>DECR2_ARATH (Q9LTV6) Peroxisomal 2,4-dienoyl-CoA reductase (EC 1.3.1.34)| Length = 298 Score = 187 bits (475), Expect = 2e-47 Identities = 89/131 (67%), Positives = 112/131 (85%) Frame = +1 Query: 163 ESPFRADVLRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGL 342 +SPF+ DV+RG+ ALITGGGSGI FEI++Q +HGA +AIMGRR++VLD AV+ALRS G+ Sbjct: 2 DSPFKPDVVRGQVALITGGGSGIGFEISSQFGKHGASIAIMGRRKQVLDDAVSALRSLGI 61 Query: 343 RAVGFQGDVRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDT 522 +A+G +GDVR QEDA RV+ +T +HFGKLDILVN AAGNFLA+ EDL+P GFRTVL+ID Sbjct: 62 QAIGLEGDVRKQEDARRVVEATFQHFGKLDILVNAAAGNFLAAAEDLSPNGFRTVLDIDA 121 Query: 523 VGTYTMCYEAL 555 VGT+ MC+ AL Sbjct: 122 VGTFNMCHAAL 132
>DECR2_BRARE (Q6NV34) Peroxisomal 2,4-dienoyl-CoA reductase (EC 1.3.1.34)| (2,4-dienoyl-CoA reductase 2) Length = 300 Score = 95.5 bits (236), Expect = 9e-20 Identities = 53/122 (43%), Positives = 70/122 (57%), Gaps = 1/122 (0%) Frame = +1 Query: 172 FRADVLRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSE-GLRA 348 + D+L + A ITGGGSGI F IA L RHG I R E + +A L S G R Sbjct: 28 YSPDLLSDQVAFITGGGSGIGFRIAEVLMRHGCDTVIASRNLEKISQAAKKLTSTTGRRC 87 Query: 349 VGFQGDVRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVG 528 + DVR E + T++ FG++DIL+N AAGNFL L+ F+TV+EIDT+G Sbjct: 88 LPIAMDVRQPETILAAVDETLKTFGRVDILINNAAGNFLCPATSLSFNAFKTVMEIDTMG 147 Query: 529 TY 534 T+ Sbjct: 148 TF 149
>DECR2_MOUSE (Q9WV68) Peroxisomal 2,4-dienoyl-CoA reductase (EC 1.3.1.34)| (2,4-dienoyl-CoA reductase 2) Length = 292 Score = 94.4 bits (233), Expect = 2e-19 Identities = 51/124 (41%), Positives = 73/124 (58%), Gaps = 1/124 (0%) Frame = +1 Query: 172 FRADVLRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRR-REVLDKAVAALRSEGLRA 348 F D+L+ K A ITGGGSGI F IA RHG H I+GR ++V A + + G R Sbjct: 21 FCPDLLQDKVAFITGGGSGIGFRIAEIFMRHGCHTVIVGRSLQKVTTAAKKLVAATGKRC 80 Query: 349 VGFQGDVRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVG 528 + DVR + + ++ FGK++IL+N AAGNFL L+ F+TV++IDT+G Sbjct: 81 LPLSMDVRVPPEVMTAVDQALQEFGKINILINCAAGNFLCPASALSFNAFKTVVDIDTIG 140 Query: 529 TYTM 540 T+ + Sbjct: 141 TFNV 144
>DECR2_RAT (Q9Z2M4) Peroxisomal 2,4-dienoyl-CoA reductase (EC 1.3.1.34)| (2,4-dienoyl-CoA reductase 2) (DCR-AKL) (pVI-AKL) Length = 292 Score = 90.5 bits (223), Expect = 3e-18 Identities = 51/124 (41%), Positives = 70/124 (56%), Gaps = 1/124 (0%) Frame = +1 Query: 172 FRADVLRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAAL-RSEGLRA 348 F D+L+ K A ITGGGSGI F IA RHG H I+ R + +A L + G R Sbjct: 21 FCPDLLQDKVAFITGGGSGIGFRIAEIFMRHGCHTVIVSRSLPRVSEAAKKLVAATGKRC 80 Query: 349 VGFQGDVRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVG 528 + DVR + ++ FGK+DIL+N AAGNFL L+ F+TV++IDT+G Sbjct: 81 LPLSMDVRVPPAVMAAVDQALKEFGKIDILINCAAGNFLCPASALSFNAFKTVVDIDTLG 140 Query: 529 TYTM 540 T+ + Sbjct: 141 TFNV 144
>DECR2_PONPY (Q5RBV3) Peroxisomal 2,4-dienoyl-CoA reductase (EC 1.3.1.34)| (2,4-dienoyl-CoA reductase 2) Length = 292 Score = 88.6 bits (218), Expect = 1e-17 Identities = 52/124 (41%), Positives = 67/124 (54%), Gaps = 1/124 (0%) Frame = +1 Query: 172 FRADVLRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRR-EVLDKAVAALRSEGLRA 348 F D+LR K A ITGGGSGI F IA RHG H I R VL A + G R Sbjct: 21 FCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRC 80 Query: 349 VGFQGDVRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVG 528 + DVR + ++ FG++DIL+N AAGNFL L+ F+TV++IDT G Sbjct: 81 LPLSMDVRAPPAIVAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSG 140 Query: 529 TYTM 540 T+ + Sbjct: 141 TFNV 144
>DECR2_HUMAN (Q9NUI1) Peroxisomal 2,4-dienoyl-CoA reductase (EC 1.3.1.34)| (2,4-dienoyl-CoA reductase 2) (pDCR) Length = 292 Score = 88.6 bits (218), Expect = 1e-17 Identities = 52/124 (41%), Positives = 67/124 (54%), Gaps = 1/124 (0%) Frame = +1 Query: 172 FRADVLRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRR-EVLDKAVAALRSEGLRA 348 F D+LR K A ITGGGSGI F IA RHG H I R VL A + G R Sbjct: 21 FCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRC 80 Query: 349 VGFQGDVRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVG 528 + DVR + ++ FG++DIL+N AAGNFL L+ F+TV++IDT G Sbjct: 81 LPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSG 140 Query: 529 TYTM 540 T+ + Sbjct: 141 TFNV 144
>PECR_MOUSE (Q99MZ7) Peroxisomal trans-2-enoyl-CoA reductase (EC 1.3.1.38)| Length = 303 Score = 87.8 bits (216), Expect = 2e-17 Identities = 46/134 (34%), Positives = 76/134 (56%), Gaps = 5/134 (3%) Frame = +1 Query: 163 ESPFRADVLRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALR---- 330 +S A +L+ + A++TGGG+GI ++ +L G +V I R+ + L AV LR Sbjct: 8 QSYLAAGLLKNQVAVVTGGGTGIGKAVSRELLHLGCNVVIASRKLDRLTAAVDELRASLP 67 Query: 331 -SEGLRAVGFQGDVRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTV 507 S Q ++R +E+ + ++ ST+ +GK++ LVN G F+A ED+T KG+ V Sbjct: 68 PSSSAEVSAIQCNIRKEEEVSNLVKSTLAKYGKINFLVNNGGGQFMAPVEDITAKGWHAV 127 Query: 508 LEIDTVGTYTMCYE 549 +E + GT+ MC E Sbjct: 128 IETNLTGTFYMCKE 141
>PECR_RAT (Q9WVK3) Peroxisomal trans-2-enoyl-CoA reductase (EC 1.3.1.38)| (RLF98) (Peroxisomal 2,4-dienoyl CoA reductase px-2,4-DCR1) Length = 303 Score = 86.7 bits (213), Expect = 4e-17 Identities = 46/132 (34%), Positives = 76/132 (57%), Gaps = 5/132 (3%) Frame = +1 Query: 163 ESPFRADVLRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALR---- 330 +S A +L+ + A++TGG +GI I+ +L G +V I R+ + L AV LR Sbjct: 8 QSYLAAGLLQNQVAVVTGGATGIGKAISRELLHLGCNVVIASRKLDRLTAAVDELRASQP 67 Query: 331 -SEGLRAVGFQGDVRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTV 507 S + Q ++R +E+ ++ ST+ +GK++ LVN A G F+A ED+T KG++ V Sbjct: 68 PSSSTQVTAIQCNIRKEEEVNNLVKSTLAKYGKINFLVNNAGGQFMAPAEDITAKGWQAV 127 Query: 508 LEIDTVGTYTMC 543 +E + GT+ MC Sbjct: 128 IETNLTGTFYMC 139
>YKUF_BACSU (O34717) Hypothetical oxidoreductase ykuF (EC 1.-.-.-)| Length = 254 Score = 86.3 bits (212), Expect = 5e-17 Identities = 47/119 (39%), Positives = 71/119 (59%) Frame = +1 Query: 196 KAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGDVRN 375 KA +ITGG SG+ +A + A G HV + GR E L++ +++ + FQ DVR+ Sbjct: 4 KAVIITGGSSGMGKAMAKKQAELGWHVMVTGRNHEALEETKKEIQTFEGQVACFQMDVRS 63 Query: 376 QEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVGTYTMCYEA 552 A+ ++ V+ FG+LD L+N AAGNF+ E LTP G++ V+EI GT+ C +A Sbjct: 64 DSAASDMIKEAVKAFGRLDALINNAAGNFICPAEKLTPNGWKAVIEIVLNGTF-FCSQA 121
>PECR_PONPY (Q5RCH8) Peroxisomal trans-2-enoyl-CoA reductase (EC 1.3.1.38)| Length = 303 Score = 84.7 bits (208), Expect = 2e-16 Identities = 44/125 (35%), Positives = 74/125 (59%), Gaps = 5/125 (4%) Frame = +1 Query: 184 VLRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRS-----EGLRA 348 +L+G+ A++TGG +GI I +L G++V I R+ E L A L++ + R Sbjct: 15 LLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAAGELQANLPPTKQARV 74 Query: 349 VGFQGDVRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVG 528 + Q ++RN+E+ ++ ST++ FGK++ LVN G FL+ E ++ KG+ VLE + G Sbjct: 75 IPIQCNIRNEEEVNNLVKSTLDIFGKINFLVNNGGGQFLSLAEHISSKGWHAVLETNLTG 134 Query: 529 TYTMC 543 T+ MC Sbjct: 135 TFYMC 139
>PECR_HUMAN (Q9BY49) Peroxisomal trans-2-enoyl-CoA reductase (EC 1.3.1.38)| (TERP) (HPDHase) (pVI-ARL) (2,4-dienoyl-CoA reductase-related protein) (DCR-RP) Length = 303 Score = 84.7 bits (208), Expect = 2e-16 Identities = 44/125 (35%), Positives = 74/125 (59%), Gaps = 5/125 (4%) Frame = +1 Query: 184 VLRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRS-----EGLRA 348 +L+G+ A++TGG +GI I +L G++V I R+ E L A L++ + R Sbjct: 15 LLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARV 74 Query: 349 VGFQGDVRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVG 528 + Q ++RN+E+ ++ ST++ FGK++ LVN G FL+ E ++ KG+ VLE + G Sbjct: 75 IPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTG 134 Query: 529 TYTMC 543 T+ MC Sbjct: 135 TFYMC 139
>SPS19_YEAST (P32573) Peroxisomal 2,4-dienoyl-CoA reductase SPS19 (EC 1.3.1.34)| (Sporulation-specific protein SPX19) Length = 291 Score = 84.0 bits (206), Expect = 3e-16 Identities = 46/130 (35%), Positives = 72/130 (55%), Gaps = 5/130 (3%) Frame = +1 Query: 160 TESPFRADVLRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRS-- 333 TE +R D+ +GK A +TGG IC L G AI+GR +E ++A + Sbjct: 12 TEGSWRPDLFKGKVAFVTGGAGTICRVQTEALVLLGCKAAIVGRDQERTEQAAKGISQLA 71 Query: 334 ---EGLRAVGFQGDVRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRT 504 + + A+ DVRN E + TVE FGK+D ++ GAAGNF+ +L+P F++ Sbjct: 72 KDKDAVLAIA-NVDVRNFEQVENAVKKTVEKFGKIDFVIAGAAGNFVCDFANLSPNAFKS 130 Query: 505 VLEIDTVGTY 534 V++ID +G++ Sbjct: 131 VVDIDLLGSF 140
>PECR_CAVPO (Q9JIF5) Peroxisomal trans-2-enoyl-CoA reductase (EC 1.3.1.38)| Length = 302 Score = 83.6 bits (205), Expect = 3e-16 Identities = 45/128 (35%), Positives = 72/128 (56%), Gaps = 5/128 (3%) Frame = +1 Query: 184 VLRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALR-----SEGLRA 348 +L+ +AA++TGGG+GI IA +L G +V I R+ + L A L+ S Sbjct: 15 LLQNRAAIVTGGGTGIGKAIAKELLHLGCNVVIASRKFDRLRAAAEELKATLPPSNKAEV 74 Query: 349 VGFQGDVRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVG 528 Q ++R +E+ ++ ST+ +GK+D LVN G F +SPE ++ KG+ V+E + G Sbjct: 75 TPIQCNIRKEEEVNNLMKSTLALYGKIDFLVNNGGGQFWSSPEHISSKGWHAVIETNLTG 134 Query: 529 TYTMCYEA 552 T+ MC A Sbjct: 135 TFYMCKAA 142
>DHRS4_PONPY (Q5RCF8) Dehydrogenase/reductase SDR family member 4 (EC 1.1.1.184)| (NADPH-dependent carbonyl reductase/NADP-retinol dehydrogenase) (CR) (PHCR) (Peroxisomal short-chain alcohol dehydrogenase) (NADPH-dependent retinol dehydrogenase/reductase) Length = 260 Score = 82.4 bits (202), Expect = 8e-16 Identities = 50/123 (40%), Positives = 72/123 (58%), Gaps = 1/123 (0%) Frame = +1 Query: 154 MATESPFRADVLRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRS 333 MA+ R D L K AL+T GI F IA +LA+ GAHV + R+++ +D+AVA L+ Sbjct: 1 MASSGMTRRDPLANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQG 60 Query: 334 EGLRAVGFQGDVRNQEDAARVLASTVEHFGKLDILVNGAAGN-FLASPEDLTPKGFRTVL 510 EGL G V ED R++A+ V+ G +DILV+ AA N F S D+T + + L Sbjct: 61 EGLSVTGTVCHVGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSLMDVTEEVWDKTL 120 Query: 511 EID 519 +I+ Sbjct: 121 DIN 123
>DHRS4_HUMAN (Q9BTZ2) Dehydrogenase/reductase SDR family member 4 (EC 1.1.1.184)| (NADPH-dependent carbonyl reductase/NADP-retinol dehydrogenase) (CR) (PHCR) (Peroxisomal short-chain alcohol dehydrogenase) (NADPH-dependent retinol dehydrogenase/reductase) Length = 260 Score = 82.4 bits (202), Expect = 8e-16 Identities = 50/123 (40%), Positives = 72/123 (58%), Gaps = 1/123 (0%) Frame = +1 Query: 154 MATESPFRADVLRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRS 333 MA+ R D L K AL+T GI F IA +LA+ GAHV + R+++ +D+AVA L+ Sbjct: 1 MASSGMTRRDPLANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQG 60 Query: 334 EGLRAVGFQGDVRNQEDAARVLASTVEHFGKLDILVNGAAGN-FLASPEDLTPKGFRTVL 510 EGL G V ED R++A+ V+ G +DILV+ AA N F S D+T + + L Sbjct: 61 EGLSVTGTVCHVGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTL 120 Query: 511 EID 519 +I+ Sbjct: 121 DIN 123
>VER1_ASPPA (P50161) Versicolorin reductase (EC 1.1.-.-) (VER-1)| Length = 262 Score = 80.5 bits (197), Expect = 3e-15 Identities = 46/123 (37%), Positives = 66/123 (53%), Gaps = 1/123 (0%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAI-MGRRREVLDKAVAALRSEGLRAVGFQG 363 L GK AL+TG G GI IA L GA V + RE +K V +++ G A+ Q Sbjct: 7 LDGKVALVTGAGRGIGAAIAVALGERGAKVVVNYAHSREAAEKVVEQIKANGTDAIAIQA 66 Query: 364 DVRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVGTYTMC 543 DV + E A+++A TV HFG LDI+ + A +D+TP+ F V ++T G + + Sbjct: 67 DVGDPEATAKLMAETVRHFGYLDIVSSNAGIVSFGHLKDVTPEEFDRVFRVNTRGQFFVA 126 Query: 544 YEA 552 EA Sbjct: 127 REA 129
>DHRS4_RABIT (Q9GKX2) Dehydrogenase/reductase SDR family member 4 (EC 1.1.1.184)| (NADPH-dependent carbonyl reductase/NADP-retinol dehydrogenase) (CR) (PHCR) (Peroxisomal short-chain alcohol dehydrogenase) (NADPH-dependent retinol dehydrogenase/reductase) Length = 260 Score = 80.1 bits (196), Expect = 4e-15 Identities = 48/123 (39%), Positives = 72/123 (58%), Gaps = 1/123 (0%) Frame = +1 Query: 154 MATESPFRADVLRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRS 333 MA+ R D L K A++T GI IA +LA+ GAHV I R+++ +D+AVAAL++ Sbjct: 1 MASSGVTRRDPLANKVAIVTASTDGIGLAIARRLAQDGAHVVISSRKQQNVDRAVAALQA 60 Query: 334 EGLRAVGFQGDVRNQEDAARVLASTVEHFGKLDILVNGAAGN-FLASPEDLTPKGFRTVL 510 EGL G V ED R++A+ + G +DILV+ AA N F D+T + + +L Sbjct: 61 EGLSVTGTVCHVGKAEDRERLVATALNLHGGIDILVSNAAVNPFFGKLMDVTEEVWDKIL 120 Query: 511 EID 519 +I+ Sbjct: 121 DIN 123
>YXEK_CAEEL (Q93761) Hypothetical oxidoreductase F53C11.3 (EC 1.-.-.-)| Length = 313 Score = 79.7 bits (195), Expect = 5e-15 Identities = 48/117 (41%), Positives = 67/117 (57%), Gaps = 2/117 (1%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSE-GLRAVGFQG 363 L GK AL+TGGG+G+ IA A GA VAI RR +VL+K +RS G FQ Sbjct: 24 LNGKVALVTGGGTGLGKAIATTFAHLGASVAIAARRLDVLEKTADEIRSSTGGVCEPFQM 83 Query: 364 DVRNQEDAARVLASTVEHFGKL-DILVNGAAGNFLASPEDLTPKGFRTVLEIDTVGT 531 DV++ A+ + + G DIL+N AAGNF+ + E L+P + T+++I GT Sbjct: 84 DVKDPAKVAKAFDAVEKKLGHTPDILINNAAGNFIMATERLSPNAYGTIIDIVLKGT 140
>DHRS4_MOUSE (Q99LB2) Dehydrogenase/reductase SDR family member 4 (EC 1.1.1.184)| (NADPH-dependent carbonyl reductase/NADP-retinol dehydrogenase) (CR) (PHCR) (Peroxisomal short-chain alcohol dehydrogenase) (NADPH-dependent retinol dehydrogenase/reductase) Length = 260 Score = 77.8 bits (190), Expect = 2e-14 Identities = 47/130 (36%), Positives = 71/130 (54%), Gaps = 1/130 (0%) Frame = +1 Query: 154 MATESPFRADVLRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRS 333 MA+ R + L K AL+T GI F IA +LA GAHV + R+++ +D+AVA L+ Sbjct: 1 MASSGLTRRNPLSNKVALVTASTDGIGFAIARRLAEDGAHVVVSSRKQQNVDRAVATLQG 60 Query: 334 EGLRAVGFQGDVRNQEDAARVLASTVEHFGKLDILVNGAAGN-FLASPEDLTPKGFRTVL 510 EGL G V ED +++ + ++ +DILV+ AA N F + D+T + + VL Sbjct: 61 EGLSVTGIVCHVGKAEDREKLITTALKRHRGIDILVSNAAVNPFFGNLMDVTEEVWDKVL 120 Query: 511 EIDTVGTYTM 540 I+ T M Sbjct: 121 SINVTATAMM 130
>DHRS4_BOVIN (Q8SPU8) Dehydrogenase/reductase SDR family member 4 (EC 1.1.1.184)| (NADPH-dependent carbonyl reductase/NADP-retinol dehydrogenase) (CR) (PHCR) (Peroxisomal short-chain alcohol dehydrogenase) (NADPH-dependent retinol dehydrogenase/reductase) Length = 260 Score = 76.6 bits (187), Expect = 4e-14 Identities = 46/127 (36%), Positives = 71/127 (55%), Gaps = 1/127 (0%) Frame = +1 Query: 154 MATESPFRADVLRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRS 333 MA+ R + L K AL+T GI F IA +LA+ GAHV + R+++ +D+AVA L+ Sbjct: 1 MASCGMARRNPLDNKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDRAVATLKG 60 Query: 334 EGLRAVGFQGDVRNQEDAARVLASTVEHFGKLDILV-NGAAGNFLASPEDLTPKGFRTVL 510 EGL G V ED R++A+ V+ G +DIL+ N A F S D+ + + +L Sbjct: 61 EGLSVTGTVCHVGKAEDRERLVATAVKLHGGVDILISNAAVSPFFGSLMDVPEEVWDKIL 120 Query: 511 EIDTVGT 531 +++ T Sbjct: 121 DVNVKAT 127
>DHRS2_HUMAN (Q13268) Dehydrogenase/reductase SDR family member 2 (EC 1.1.-.-)| (HEP27 protein) (Protein D) Length = 257 Score = 76.3 bits (186), Expect = 6e-14 Identities = 44/111 (39%), Positives = 63/111 (56%), Gaps = 5/111 (4%) Frame = +1 Query: 175 RADVLRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVG 354 R VL + A++TG SGI F IA +LAR GAHV I R+++ +D+A+A L+ EGL G Sbjct: 7 RKGVLANRVAVVTGSTSGIGFAIARRLARDGAHVVISSRKQQNVDRAMAKLQGEGLSVAG 66 Query: 355 FQGDVRNQEDAARVLASTVEHFGKLDIL-----VNGAAGNFLASPEDLTPK 492 V ED +++A +EH G +D L VN G+ L + E + K Sbjct: 67 IVCHVGKAEDREQLVAKALEHCGGVDFLVCSAGVNPLVGSTLGTSEQIWDK 117
>DHRS4_PIG (Q8WNV7) Dehydrogenase/reductase SDR family member 4 (EC 1.1.1.184)| (NADPH-dependent carbonyl reductase/NADP-retinol dehydrogenase) (CR) (PHCR) (Peroxisomal short-chain alcohol dehydrogenase) (NADPH-dependent retinol dehydrogenase/reductase) (N Length = 260 Score = 75.5 bits (184), Expect = 1e-13 Identities = 48/130 (36%), Positives = 68/130 (52%), Gaps = 1/130 (0%) Frame = +1 Query: 154 MATESPFRADVLRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRS 333 MA+ R L K AL+T GI IA +LA+ GAHV + R++E +D+ VA L+ Sbjct: 1 MASTGVERRKPLENKVALVTASTDGIGLAIARRLAQDGAHVVVSSRKQENVDRTVATLQG 60 Query: 334 EGLRAVGFQGDVRNQEDAARVLASTVEHFGKLDILVNGAAGN-FLASPEDLTPKGFRTVL 510 EGL G V ED R++A V G +DILV+ AA N F + D T + + +L Sbjct: 61 EGLSVTGTVCHVGKAEDRERLVAMAVNLHGGVDILVSNAAVNPFFGNIIDATEEVWDKIL 120 Query: 511 EIDTVGTYTM 540 ++ T M Sbjct: 121 HVNVKATVLM 130
>YVX3_CAEEL (Q22230) Hypothetical oxidoreductase T05C12.3 (EC 1.-.-.-)| Length = 309 Score = 74.7 bits (182), Expect = 2e-13 Identities = 49/127 (38%), Positives = 70/127 (55%), Gaps = 2/127 (1%) Frame = +1 Query: 175 RADVLRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDK-AVAALRSEGLRAV 351 R L+GK AL+TGGG+GI IA A GA VAI RR E L++ A +++ G Sbjct: 19 RDGALKGKVALVTGGGTGIGKAIATTFAHLGASVAIAARRMEKLEQTAEEIMKTTGGICE 78 Query: 352 GFQGDVRNQEDAARVLASTVEHFGK-LDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVG 528 F+ D+++ + + FGK DILVN AAGNF+ + E L+P T+++I G Sbjct: 79 PFRMDIKDPGMVSDTFDKIDKKFGKHPDILVNNAAGNFIMATERLSPNAHGTIIDIVLKG 138 Query: 529 TYTMCYE 549 T + E Sbjct: 139 TMNVTTE 145
>STCU_EMENI (Q00791) Versicolorin reductase (EC 1.1.-.-)| Length = 264 Score = 74.7 bits (182), Expect = 2e-13 Identities = 45/134 (33%), Positives = 68/134 (50%), Gaps = 1/134 (0%) Frame = +1 Query: 154 MATESPFRADVLRGKAALITGGGSGICFEIAAQLARHGAHVAI-MGRRREVLDKAVAALR 330 M++ +R D GK AL+TG G GI IA L + GA V + RE +K V ++ Sbjct: 1 MSSSDNYRLD---GKVALVTGAGRGIGAAIAVALGQRGAKVVVNYANSREAAEKVVDEIK 57 Query: 331 SEGLRAVGFQGDVRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVL 510 S A+ Q DV + + +++ VEHFG LDI+ + A +D+TP F V Sbjct: 58 SNAQTAISIQADVGDPDAVTKLMDQAVEHFGYLDIVSSNAGIVSFGHVKDVTPDEFDRVF 117 Query: 511 EIDTVGTYTMCYEA 552 ++T G + + EA Sbjct: 118 RVNTRGQFFVAREA 131
>DHRS4_RAT (Q8VID1) Dehydrogenase/reductase SDR family member 4 (EC 1.1.1.184)| (NADPH-dependent carbonyl reductase/NADP-retinol dehydrogenase) (CR) (PHCR) (Peroxisomal short-chain alcohol dehydrogenase) (NADPH-dependent retinol dehydrogenase/reductase) (N Length = 260 Score = 71.6 bits (174), Expect = 1e-12 Identities = 46/130 (35%), Positives = 69/130 (53%), Gaps = 1/130 (0%) Frame = +1 Query: 154 MATESPFRADVLRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRS 333 MA+ R + L K AL+T GI IA +LA GAHV I R+++ +D+AVA L+ Sbjct: 1 MASSGLTRQNPLANKVALVTASTDGIGLAIARRLAEDGAHVVISSRKQQNVDRAVATLQG 60 Query: 334 EGLRAVGFQGDVRNQEDAARVLASTVEHFGKLDILVNGAAGN-FLASPEDLTPKGFRTVL 510 EGL G V ED +++ ++ +DILV+ AA N F + D+T + + VL Sbjct: 61 EGLSVTGVVCHVGKAEDREKLVNMALKLHQGIDILVSNAAVNPFFGNLMDVTEEVWNKVL 120 Query: 511 EIDTVGTYTM 540 I+ + M Sbjct: 121 SINVTASAMM 130
>T4HR_MAGGR (Q12634) Tetrahydroxynaphthalene reductase (EC 1.1.1.252) (T4HN| reductase) (THNR) Length = 282 Score = 69.7 bits (169), Expect = 5e-12 Identities = 43/123 (34%), Positives = 64/123 (52%), Gaps = 1/123 (0%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAI-MGRRREVLDKAVAALRSEGLRAVGFQG 363 L GK AL+TG G GI E+A +L R G V + E ++ VAA++ G A + Sbjct: 26 LEGKVALVTGAGRGIGREMAMELGRRGCKVIVNYANSTESAEEVVAAIKKNGSDAACVKA 85 Query: 364 DVRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVGTYTMC 543 +V ED R+ V+ FGKLDI+ + + +D+TP+ F V I+T G + + Sbjct: 86 NVGVVEDIVRMFEEAVKIFGKLDIVCSNSGVVSFGHVKDVTPEEFDRVFTINTRGQFFVA 145 Query: 544 YEA 552 EA Sbjct: 146 REA 148
>DECR_MOUSE (Q9CQ62) 2,4-dienoyl-CoA reductase, mitochondrial precursor (EC| 1.3.1.34) (2,4-dienoyl-CoA reductase [NADPH]) (4-enoyl-CoA reductase [NADPH]) Length = 335 Score = 68.9 bits (167), Expect = 9e-12 Identities = 39/118 (33%), Positives = 63/118 (53%), Gaps = 1/118 (0%) Frame = +1 Query: 181 DVLRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSE-GLRAVGF 357 D +GK A ITGGG+G+ + L+ GA I R +VL + S+ G + Sbjct: 55 DAFQGKVAFITGGGTGLGKAMTTFLSTLGAQCVIASRNIDVLKATAEEISSKTGNKVHAI 114 Query: 358 QGDVRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVGT 531 + DVR+ + + ++ G D+++N AAGNF++ E LTP G++T+ +I GT Sbjct: 115 RCDVRDPDMVHNTVLELIKVAGHPDVVINNAAGNFISPSERLTPNGWKTITDIVLNGT 172
>BUTA_STAAW (P66776) Acetoin(diacetyl) reductase (EC 1.1.1.5) (Acetoin| dehydrogenase) (AR) (Meso-2,3-butanediol dehydrogenase) Length = 258 Score = 68.6 bits (166), Expect = 1e-11 Identities = 36/111 (32%), Positives = 56/111 (50%) Frame = +1 Query: 196 KAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGDVRN 375 K AL+TGG GI F+IA +L G VA++ E A L S+G +A+ + DV N Sbjct: 5 KVALVTGGAQGIGFKIAERLVEDGFKVAVVDFNEEGAKAAALKLSSDGTKAIAIKADVSN 64 Query: 376 QEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVG 528 ++D + T FG ++VN A + +T + F+TV ++ G Sbjct: 65 RDDVFNAVRQTAAQFGDFHVMVNNAGLGPTTPIDTITEEQFKTVYGVNVAG 115
>BUTA_STAAS (Q6GCZ8) Acetoin(diacetyl) reductase (EC 1.1.1.5) (Acetoin| dehydrogenase) (AR) (Meso-2,3-butanediol dehydrogenase) Length = 258 Score = 68.6 bits (166), Expect = 1e-11 Identities = 36/111 (32%), Positives = 56/111 (50%) Frame = +1 Query: 196 KAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGDVRN 375 K AL+TGG GI F+IA +L G VA++ E A L S+G +A+ + DV N Sbjct: 5 KVALVTGGAQGIGFKIAERLVEDGFKVAVVDFNEEGAKAAALKLSSDGTKAIAIKADVSN 64 Query: 376 QEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVG 528 ++D + T FG ++VN A + +T + F+TV ++ G Sbjct: 65 RDDVFNAVRQTAAQFGDFHVMVNNAGLGPTTPIDTITEEQFKTVYGVNVAG 115
>BUTA_STAAR (Q6GKH9) Acetoin(diacetyl) reductase (EC 1.1.1.5) (Acetoin| dehydrogenase) (AR) (Meso-2,3-butanediol dehydrogenase) Length = 258 Score = 68.6 bits (166), Expect = 1e-11 Identities = 36/111 (32%), Positives = 56/111 (50%) Frame = +1 Query: 196 KAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGDVRN 375 K AL+TGG GI F+IA +L G VA++ E A L S+G +A+ + DV N Sbjct: 5 KVALVTGGAQGIGFKIAERLVEDGFKVAVVDFNEEGAKAAALKLSSDGTKAIAIKADVSN 64 Query: 376 QEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVG 528 ++D + T FG ++VN A + +T + F+TV ++ G Sbjct: 65 RDDVFNAVRQTAAQFGDFHVMVNNAGLGPTTPIDTITEEQFKTVYGVNVAG 115
>BUTA_STAAN (P99120) Acetoin(diacetyl) reductase (EC 1.1.1.5) (Acetoin| dehydrogenase) (AR) (Meso-2,3-butanediol dehydrogenase) Length = 258 Score = 68.6 bits (166), Expect = 1e-11 Identities = 36/111 (32%), Positives = 56/111 (50%) Frame = +1 Query: 196 KAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGDVRN 375 K AL+TGG GI F+IA +L G VA++ E A L S+G +A+ + DV N Sbjct: 5 KVALVTGGAQGIGFKIAERLVEDGFKVAVVDFNEEGAKAAALKLSSDGTKAIAIKADVSN 64 Query: 376 QEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVG 528 ++D + T FG ++VN A + +T + F+TV ++ G Sbjct: 65 RDDVFNAVRQTAAQFGDFHVMVNNAGLGPTTPIDTITEEQFKTVYGVNVAG 115
>BUTA_STAAM (P66775) Acetoin(diacetyl) reductase (EC 1.1.1.5) (Acetoin| dehydrogenase) (AR) (Meso-2,3-butanediol dehydrogenase) Length = 258 Score = 68.6 bits (166), Expect = 1e-11 Identities = 36/111 (32%), Positives = 56/111 (50%) Frame = +1 Query: 196 KAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGDVRN 375 K AL+TGG GI F+IA +L G VA++ E A L S+G +A+ + DV N Sbjct: 5 KVALVTGGAQGIGFKIAERLVEDGFKVAVVDFNEEGAKAAALKLSSDGTKAIAIKADVSN 64 Query: 376 QEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVG 528 ++D + T FG ++VN A + +T + F+TV ++ G Sbjct: 65 RDDVFNAVRQTAAQFGDFHVMVNNAGLGPTTPIDTITEEQFKTVYGVNVAG 115
>BUTA_STAAC (Q5HJP2) Acetoin(diacetyl) reductase (EC 1.1.1.5) (Acetoin| dehydrogenase) (AR) (Meso-2,3-butanediol dehydrogenase) Length = 258 Score = 68.6 bits (166), Expect = 1e-11 Identities = 36/111 (32%), Positives = 56/111 (50%) Frame = +1 Query: 196 KAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGDVRN 375 K AL+TGG GI F+IA +L G VA++ E A L S+G +A+ + DV N Sbjct: 5 KVALVTGGAQGIGFKIAERLVEDGFKVAVVDFNEEGAKAAALKLSSDGTKAIAIKADVSN 64 Query: 376 QEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVG 528 ++D + T FG ++VN A + +T + F+TV ++ G Sbjct: 65 RDDVFNAVRQTAAQFGDFHVMVNNAGLGPTTPIDTITEEQFKTVYGVNVAG 115
>YXJF_BACSU (P42317) Hypothetical oxidoreductase yxjF (EC 1.-.-.-)| Length = 257 Score = 68.2 bits (165), Expect = 2e-11 Identities = 38/110 (34%), Positives = 56/110 (50%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGD 366 +R + AL+TG GI FEIA + AR GA V + R E +KA + L EG A D Sbjct: 1 MRKQVALVTGAAGGIRFEIAREFAREGASVIVSDLRPEACEKAASKLAEEGFDAAAIPYD 60 Query: 367 VRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEI 516 V + A + + +G+LDILVN A +A E+ F ++++ Sbjct: 61 VTKEAQVADTVNVIQKQYGRLDILVNNAGIQHVAPIEEFPTDTFEQLIKV 110
>YOXD_BACSU (P14802) Hypothetical oxidoreductase yoxD (EC 1.-.-.-)| Length = 238 Score = 67.0 bits (162), Expect = 3e-11 Identities = 34/116 (29%), Positives = 63/116 (54%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGD 366 L+ K ALITGGG GI A LA+ G ++ ++GR ++K +++ G++A D Sbjct: 4 LQHKTALITGGGRGIGRATALALAKEGVNIGLIGRTSANVEKVAEEVKALGVKAAFAAAD 63 Query: 367 VRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVGTY 534 V++ + + +A E G +DIL+N A + DL+ + +++++ +G Y Sbjct: 64 VKDADQVNQAVAQVKEQLGDIDILINNAGISKFGGFLDLSADEWENIIQVNLMGVY 119
>DECR_RAT (Q64591) 2,4-dienoyl-CoA reductase, mitochondrial precursor (EC| 1.3.1.34) (2,4-dienoyl-CoA reductase [NADPH]) (4-enoyl-CoA reductase [NADPH]) Length = 335 Score = 66.2 bits (160), Expect = 6e-11 Identities = 37/118 (31%), Positives = 63/118 (53%), Gaps = 1/118 (0%) Frame = +1 Query: 181 DVLRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSE-GLRAVGF 357 + +GK A ITGGG+G+ + L+ GA I R +VL + S+ G + Sbjct: 55 NAFQGKVAFITGGGTGLGKAMTTFLSSLGAQCVIASRNIDVLKATAEEITSKTGNKVYAI 114 Query: 358 QGDVRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVGT 531 + DVR+ + + ++ G D+++N AAGNF++ E L+P G++T+ +I GT Sbjct: 115 RCDVRDPDMVHNTVLELIKVAGHPDVVINNAAGNFISPSERLSPNGWKTITDIVLNGT 172
>DHK2_STRVN (P16543) Granaticin polyketide synthase putative ketoacyl reductase| 2 (EC 1.3.1.-) (ORF6) Length = 249 Score = 66.2 bits (160), Expect = 6e-11 Identities = 47/138 (34%), Positives = 71/138 (51%), Gaps = 4/138 (2%) Frame = +1 Query: 154 MATESPFRADVLRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRR-EVLDKAVAALR 330 MAT++P AL+TG SGI +A +LA G V + R E +K AAL Sbjct: 1 MATDAP------EAPVALVTGSSSGIGQTVAQRLAAEGYRVVVNSARSVEDGEKTAAALP 54 Query: 331 SEGLRAVGFQGDVRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDL---TPKGFR 501 A+ + DV + DA R++ + VEH+G+LD+LVN A DL TP+ +R Sbjct: 55 D----ALYVRADVSEEADARRLVDTAVEHYGRLDVLVNNAGRTRAIPHADLAAATPEVWR 110 Query: 502 TVLEIDTVGTYTMCYEAL 555 +L ++ +GT+ A+ Sbjct: 111 EILGLNVIGTWQTTVAAM 128
>DHR10_HUMAN (Q9BPX1) Dehydrogenase/reductase SDR family member 10 (EC 1.1.-.-)| (Retinal short-chain dehydrogenase/reductase retSDR3) Length = 270 Score = 65.9 bits (159), Expect = 8e-11 Identities = 42/122 (34%), Positives = 63/122 (51%), Gaps = 1/122 (0%) Frame = +1 Query: 193 GKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGDVR 372 GK ++TGGG GI I GA V I + + AL E AV DV Sbjct: 9 GKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKD----ESGGRALEQELPGAVFILCDVT 64 Query: 373 NQEDAARVLASTVEHFGKLDILVNGAAGNFLAS-PEDLTPKGFRTVLEIDTVGTYTMCYE 549 ++D +++ T+ FG+LD +VN A + PE+ + +GFR +LE++ +GTYT+ Sbjct: 65 QEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKL 124 Query: 550 AL 555 AL Sbjct: 125 AL 126
>DECR_HUMAN (Q16698) 2,4-dienoyl-CoA reductase, mitochondrial precursor (EC| 1.3.1.34) (2,4-dienoyl-CoA reductase [NADPH]) (4-enoyl-CoA reductase [NADPH]) Length = 335 Score = 65.9 bits (159), Expect = 8e-11 Identities = 37/115 (32%), Positives = 63/115 (54%), Gaps = 1/115 (0%) Frame = +1 Query: 190 RGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSE-GLRAVGFQGD 366 +GK A ITGGG+G+ + L+ GA I R+ +VL + S+ G + Q D Sbjct: 58 QGKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATAEQISSQTGNKVHAIQCD 117 Query: 367 VRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVGT 531 VR+ + ++ ++ G +I++N AAGNF++ E L+P ++T+ +I GT Sbjct: 118 VRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPNAWKTITDIVLNGT 172
>TODD_PSEPU (P13859) Cis-toluene dihydrodiol dehydrogenase (EC 1.3.1.-)| Length = 275 Score = 65.5 bits (158), Expect = 1e-10 Identities = 45/123 (36%), Positives = 63/123 (51%), Gaps = 9/123 (7%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRS----EGLRAVG 354 L G+ AL+TGGG+G+ I + GA VA VLDK+ A L + G VG Sbjct: 3 LEGEVALVTGGGAGLGRAIVDRYVAEGARVA-------VLDKSAAGLEALRKLHGDAIVG 55 Query: 355 FQGDVRNQEDAARVLASTVEHFGKLDILV-NGAAGNFLAS----PEDLTPKGFRTVLEID 519 +GDVR+ + +A VE FGKLD LV N ++L P+DL + F + E++ Sbjct: 56 VEGDVRSLDSHREAVARCVEAFGKLDCLVGNAGVWDYLTQLVDIPDDLISEAFEEMFEVN 115 Query: 520 TVG 528 G Sbjct: 116 VKG 118
>BNZE_PSEPU (P08088) Cis-1,2-dihydrobenzene-1,2-diol dehydrogenase (EC| 1.3.1.19) (Cis-benzene glycol dehydrogenase) Length = 275 Score = 65.5 bits (158), Expect = 1e-10 Identities = 45/123 (36%), Positives = 63/123 (51%), Gaps = 9/123 (7%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRS----EGLRAVG 354 L G+ AL+TGGG+G+ I + GA VA VLDK+ A L + G VG Sbjct: 3 LEGEVALVTGGGAGLGRAIVDRYVAEGARVA-------VLDKSAAGLEALRKLHGDAIVG 55 Query: 355 FQGDVRNQEDAARVLASTVEHFGKLDILV-NGAAGNFLAS----PEDLTPKGFRTVLEID 519 +GDVR+ + +A VE FGKLD LV N ++L P+DL + F + E++ Sbjct: 56 VEGDVRSLDSHREAVARCVEAFGKLDCLVGNAGVWDYLTQLVDIPDDLISEAFEEMFEVN 115 Query: 520 TVG 528 G Sbjct: 116 VKG 118
>Y325_THEMA (Q9WYG0) Hypothetical oxidoreductase TM0325 (EC 1.-.-.-)| Length = 251 Score = 64.3 bits (155), Expect = 2e-10 Identities = 42/117 (35%), Positives = 61/117 (52%) Frame = +1 Query: 190 RGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGDV 369 +GK LITG GSGI + A A GA VAI E + V ++S G A GDV Sbjct: 4 QGKVVLITGAGSGIGKKAAVMFAERGAKVAINDISEEKGKETVELIKSMGGEAAFIFGDV 63 Query: 370 RNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVGTYTM 540 +DA +++ TVE FG+LDILVN A + E+ + + F + ++ G + + Sbjct: 64 --AKDAEQIVKKTVETFGRLDILVNNAGIVPYGNIEETSEEDFDKTMAVNVKGPFLL 118
>YWC4_CAEEL (Q23116) Hypothetical oxidoreductase W01C9.4 (EC 1.-.-.-)| Length = 309 Score = 64.3 bits (155), Expect = 2e-10 Identities = 43/127 (33%), Positives = 65/127 (51%), Gaps = 2/127 (1%) Frame = +1 Query: 175 RADVLRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAAL-RSEGLRAV 351 R +GK L+TGGG+GI IA A A V I RR E L++ + + G Sbjct: 19 RDGAFKGKLVLVTGGGTGIGKAIATTFAHLRATVVIAARRMEKLEQTARDITKITGGTCE 78 Query: 352 GFQGDVRNQEDAARVLASTVEHFGKL-DILVNGAAGNFLASPEDLTPKGFRTVLEIDTVG 528 FQ D+++ + FGK+ +ILVN AAGNF+ + E L+ + T+++I G Sbjct: 79 PFQMDIKDPGMVSDAFDKIDMKFGKVPEILVNNAAGNFIMATELLSSNAYGTIIDIVLKG 138 Query: 529 TYTMCYE 549 T+ + E Sbjct: 139 TFNVTTE 145
>DHR10_BOVIN (Q9MYP6) Dehydrogenase/reductase SDR family member 10 (EC 1.1.-.-)| (Retinal short-chain dehydrogenase/reductase retSDR3) Length = 270 Score = 63.9 bits (154), Expect = 3e-10 Identities = 43/123 (34%), Positives = 64/123 (52%), Gaps = 2/123 (1%) Frame = +1 Query: 193 GKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVA-ALRSEGLRAVGFQGDV 369 GK ++TGGG GI I GA V I + D+A A+ E V DV Sbjct: 9 GKVVIVTGGGRGIGAGIVRAFVESGAQVVICDK-----DEARGRAVERELPGTVFLLCDV 63 Query: 370 RNQEDAARVLASTVEHFGKLDILVNGAAGNFLAS-PEDLTPKGFRTVLEIDTVGTYTMCY 546 +ED +++ T+ FG+LD +VN A + PE+ + +GFR +LE++ +GTYT+ Sbjct: 64 TREEDVRTLVSETIRRFGRLDCIVNNAGYHPPPQWPEETSAQGFRQLLELNLLGTYTLTK 123 Query: 547 EAL 555 AL Sbjct: 124 LAL 126
>THR1_GLOLA (P87025) Trihydroxynaphthalene reductase (EC 1.1.1.-) (T3HN| reductase) Length = 272 Score = 63.9 bits (154), Expect = 3e-10 Identities = 37/123 (30%), Positives = 63/123 (51%), Gaps = 1/123 (0%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAI-MGRRREVLDKAVAALRSEGLRAVGFQG 363 L GK AL+TG G GI E+A +L R GA V + E ++ V A++ G A + Sbjct: 27 LMGKVALVTGAGRGIGREMAMELGRRGAKVIVNYANSAETAEEVVQAIKKSGSDAASIKA 86 Query: 364 DVRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVGTYTMC 543 +V + + ++ + +G+LDI+ + + +D+TP+ F V I+T G + + Sbjct: 87 NVSDVDQIVKMFGEAKQIWGRLDIVCSNSGVVSFGHVKDVTPEEFDRVFAINTRGQFFVA 146 Query: 544 YEA 552 EA Sbjct: 147 REA 149
>ACT3_STRCO (P16544) Putative ketoacyl reductase (EC 1.3.1.-)| Length = 261 Score = 63.5 bits (153), Expect = 4e-10 Identities = 38/120 (31%), Positives = 62/120 (51%) Frame = +1 Query: 196 KAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGDVRN 375 + AL+TG SGI EIA +L + G V + R E L + LR G+ A G DVR+ Sbjct: 7 EVALVTGATSGIGLEIARRLGKEGLRVFVCARGEEGLRTTLKELREAGVEADGRTCDVRS 66 Query: 376 QEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVGTYTMCYEAL 555 + ++A+ VE +G +D+LVN A + +L + + V+E + G + + + L Sbjct: 67 VPEIEALVAAVVERYGPVDVLVNNAGRPGGGATAELADELWLDVVETNLTGVFRVTKQVL 126
>GNO_GLUOX (P50199) Gluconate 5-dehydrogenase (EC 1.1.1.69)| (5-keto-D-gluconate 5-reductase) Length = 256 Score = 62.4 bits (150), Expect = 8e-10 Identities = 38/102 (37%), Positives = 53/102 (51%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGD 366 L G AL+TG GI +A LAR+GA V + GR E LD A + +EGL+A D Sbjct: 9 LSGARALVTGASRGIGLTLAKGLARYGAEVVLNGRNAESLDSAQSGFEAEGLKASTAVFD 68 Query: 367 VRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPK 492 V +Q+ +A+ G +DIL+N A A E+ + K Sbjct: 69 VTDQDAVIDGVAAIERDMGPIDILINNAGIQRRAPLEEFSRK 110
>YHDF_BACSU (O07575) Hypothetical oxidoreductase yhdF (EC 1.-.-.-)| Length = 289 Score = 62.4 bits (150), Expect = 8e-10 Identities = 35/90 (38%), Positives = 51/90 (56%), Gaps = 1/90 (1%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGR-RREVLDKAVAALRSEGLRAVGFQG 363 L+GK A+ITGG SGI A A+ GA ++I+ ++ + E +R + G Sbjct: 43 LKGKVAIITGGDSGIGRAAAIAFAKEGADISILYLDEHSDAEETRKRIEKENVRCLLIPG 102 Query: 364 DVRNQEDAARVLASTVEHFGKLDILVNGAA 453 DV ++ + + TV+HFGKLDILVN AA Sbjct: 103 DVGDENHCEQAVQQTVDHFGKLDILVNNAA 132
>GS39_BACSU (P80873) General stress protein 39 (GSP39) (EC 1.-.-.-)| Length = 285 Score = 62.0 bits (149), Expect = 1e-09 Identities = 36/92 (39%), Positives = 52/92 (56%), Gaps = 1/92 (1%) Frame = +1 Query: 178 ADVLRGKAALITGGGSGICFEIAAQLARHGAHVAIMGR-RREVLDKAVAALRSEGLRAVG 354 AD L+GK ALITGG SGI ++ A+ GA +AI+ + E ++ + EG++ + Sbjct: 36 ADKLKGKVALITGGDSGIGRAVSVAYAKEGADIAIVYKDEHEDAEETKKRVEQEGVKCLL 95 Query: 355 FQGDVRNQEDAARVLASTVEHFGKLDILVNGA 450 GDV +E + TV+ G LDILVN A Sbjct: 96 IAGDVGEEEFCNEAVEKTVKELGGLDILVNNA 127
>DHBA_BACSU (P39071) 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase (EC| 1.3.1.28) (Cold shock protein CSI14) Length = 261 Score = 61.6 bits (148), Expect = 1e-09 Identities = 36/116 (31%), Positives = 55/116 (47%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGD 366 + GK A ITG GI +A LA GAH+A + E L+K V++L++E A F D Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65 Query: 367 VRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVGTY 534 VR+ + A G +DILVN A L+ + + +++ G + Sbjct: 66 VRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVF 121
>DHG2_BACSU (P80869) Glucose 1-dehydrogenase 2 (EC 1.1.1.47) (GLCDH-II)| (GDH-II) (General stress protein 74) (GSP74) Length = 258 Score = 61.2 bits (147), Expect = 2e-09 Identities = 35/125 (28%), Positives = 66/125 (52%), Gaps = 2/125 (1%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREV-LDKAVAALRSEGLRAVGFQG 363 L GK A++TG GI IA + + +V + D+ + ++ G +AV + Sbjct: 5 LTGKTAIVTGSSKGIGKAIAERFGKEKMNVVVNYHSDPSGADETLEIIKQNGGKAVSVEA 64 Query: 364 DVRNQEDAARVLASTVEHFGKLDILVNGAAGNFL-ASPEDLTPKGFRTVLEIDTVGTYTM 540 DV +E +L + +EHFG LD++VN + N + A P +++ + ++ V++++ GT+ Sbjct: 65 DVSKEEGIQALLDTALEHFGTLDVMVNNSGFNGVEAMPHEMSLEDWQRVIDVNVTGTFLG 124 Query: 541 CYEAL 555 AL Sbjct: 125 AKAAL 129
>TRNH_DATST (P50165) Tropinone reductase homolog (EC 1.1.1.-) (P29X)| Length = 268 Score = 60.1 bits (144), Expect = 4e-09 Identities = 36/120 (30%), Positives = 57/120 (47%), Gaps = 1/120 (0%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGD 366 LRG AL+TGG GI + I +LA GA V R + LD+ + R +G + G D Sbjct: 15 LRGMTALVTGGTRGIGYAIVEELANFGAEVYTCSRSQNDLDECLEKWRRKGFKVSGPVCD 74 Query: 367 VRNQEDAARVLASTVEHF-GKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVGTYTMC 543 V + ++ S F GKL+IL+N A + T + + ++ + +Y +C Sbjct: 75 VSSISQRQTLMESVTSSFNGKLNILINNAGTTIPKEATNFTAEDYSIIMGTNFEASYNLC 134
>DHGB_BACME (P07999) Glucose 1-dehydrogenase B (EC 1.1.1.47)| Length = 262 Score = 59.7 bits (143), Expect = 5e-09 Identities = 36/127 (28%), Positives = 64/127 (50%), Gaps = 4/127 (3%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSE----GLRAVG 354 L GK +ITG +G+ +A + A A V + R +E D+A + L E G A+ Sbjct: 5 LEGKVVVITGSSTGLGKSMAIRFATEKAKVVVNYRSKE--DEANSVLEEEIKKVGGEAIA 62 Query: 355 FQGDVRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVGTY 534 +GDV + D ++ S ++ FGKLD+++N A S +++ + V++ + G + Sbjct: 63 VKGDVTVESDVINLVQSAIKEFGKLDVMINNAGMENPVSSHEMSLSDWNKVIDTNLTGAF 122 Query: 535 TMCYEAL 555 EA+ Sbjct: 123 LGSREAI 129
>TRN1_DATST (P50162) Tropinone reductase 1 (EC 1.1.1.206) (Tropinone| reductase-I) (TR-I) (Tropine dehydrogenase) Length = 273 Score = 59.3 bits (142), Expect = 7e-09 Identities = 36/117 (30%), Positives = 58/117 (49%), Gaps = 1/117 (0%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGD 366 L+G AL+TGG GI + I +LA GA V R + LD+ + R +GL G D Sbjct: 19 LKGTTALVTGGSKGIGYAIVEELAGLGARVYTCSRNEKELDECLEIWREKGLNVEGSVCD 78 Query: 367 VRNQEDAARVLASTVEHF-GKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVGTY 534 + ++ + +++ + F GKL+ILVN A +D T K + ++ + Y Sbjct: 79 LLSRTERDKLMQTVAHVFDGKLNILVNNAGVVIHKEAKDFTEKDYNIIMGTNFEAAY 135
>DHG1_BACME (P39482) Glucose 1-dehydrogenase 1 (EC 1.1.1.47) (GLCDH-I)| Length = 261 Score = 58.9 bits (141), Expect = 9e-09 Identities = 32/124 (25%), Positives = 63/124 (50%), Gaps = 1/124 (0%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGR-RREVLDKAVAALRSEGLRAVGFQG 363 L GK +ITG +G+ +A + A A V + R + E + + ++ G A+ +G Sbjct: 5 LEGKVVVITGSSTGLGKAMAIRFATEKAKVVVNYRSKEEEANSVLEEIKKVGGEAIAVKG 64 Query: 364 DVRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVGTYTMC 543 DV + D ++ S+++ FGKLD+++N A S +++ + V++ + G + Sbjct: 65 DVTVESDVINLVQSSIKEFGKLDVMINNAGMENPVSSHEMSLSDWNKVIDTNLTGAFLGS 124 Query: 544 YEAL 555 EA+ Sbjct: 125 REAI 128
>TRN2_HYONI (P50164) Tropinone reductase 2 (EC 1.1.1.236) (Tropinone| reductase-II) (TR-II) Length = 260 Score = 58.9 bits (141), Expect = 9e-09 Identities = 36/117 (30%), Positives = 57/117 (48%), Gaps = 1/117 (0%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGD 366 L G AL+TGG GI + I +LA GA V R ++ LD+ + RS+G D Sbjct: 7 LEGCTALVTGGSRGIGYGIVEELANLGASVYTCSRNQKELDECLTQWRSKGFNVEASVCD 66 Query: 367 VRNQEDAARVLASTVEHF-GKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVGTY 534 + ++ + + + HF GKL+ILVN A +D T + + ++ I+ Y Sbjct: 67 LSSRSEREEFMKTVSNHFHGKLNILVNNAGIVIYKEAKDYTMEDYSHIMSINFEAAY 123
>HDHA_ECOLI (P0AET8) 7-alpha-hydroxysteroid dehydrogenase (EC 1.1.1.159)| (7-alpha-HSDH) Length = 255 Score = 58.9 bits (141), Expect = 9e-09 Identities = 38/118 (32%), Positives = 60/118 (50%), Gaps = 2/118 (1%) Frame = +1 Query: 172 FRADVLR--GKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLR 345 F +D LR GK A+ITG G+GI EIA A GA V + + + V ++ G + Sbjct: 2 FNSDNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQ 61 Query: 346 AVGFQGDVRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEID 519 A + D+ ++++ + + + GK+DILVN A G P D+ FR E++ Sbjct: 62 AFACRCDITSEQELSALADFAISKLGKVDILVNNAGGGG-PKPFDMPMADFRRAYELN 118
>HDHA_ECO57 (P0AET9) 7-alpha-hydroxysteroid dehydrogenase (EC 1.1.1.159)| (7-alpha-HSDH) Length = 255 Score = 58.9 bits (141), Expect = 9e-09 Identities = 38/118 (32%), Positives = 60/118 (50%), Gaps = 2/118 (1%) Frame = +1 Query: 172 FRADVLR--GKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLR 345 F +D LR GK A+ITG G+GI EIA A GA V + + + V ++ G + Sbjct: 2 FNSDNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQ 61 Query: 346 AVGFQGDVRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEID 519 A + D+ ++++ + + + GK+DILVN A G P D+ FR E++ Sbjct: 62 AFACRCDITSEQELSALADFAISKLGKVDILVNNAGGGG-PKPFDMPMADFRRAYELN 118
>BDHA_RALEU (Q9X6U2) D-beta-hydroxybutyrate dehydrogenase (EC 1.1.1.30) (BDH)| (3-hydroxybutyrate dehydrogenase) (3-HBDH) Length = 258 Score = 58.9 bits (141), Expect = 9e-09 Identities = 39/118 (33%), Positives = 59/118 (50%), Gaps = 1/118 (0%) Frame = +1 Query: 184 VLRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQG 363 +L GK AL+TG SGI IA LA GA++ + G KA A +G+R VG+ G Sbjct: 1 MLNGKTALVTGSTSGIGLGIAKALAAQGANIIVNGFGDADAAKAEIAQAGQGIR-VGYHG 59 Query: 364 -DVRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVGTY 534 D+ + ++ FG DILVN A +A+ ED P+ + ++ I+ + Sbjct: 60 ADMSKAAEIEDMMRYAQSDFGGADILVNNAGIQHVAAIEDFPPERWDAIIAINLTSAF 117
>Y019_THEMA (Q56318) Putative oxidoreductase TM0019 (EC 1.-.-.-)| Length = 256 Score = 58.5 bits (140), Expect = 1e-08 Identities = 37/117 (31%), Positives = 57/117 (48%) Frame = +1 Query: 184 VLRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQG 363 +L GK A++TGGG GI IA A +G V I E + LR GL + Sbjct: 1 MLEGKVAVVTGGGQGIGAAIAQLFAENGMKVVIAEIDEEAGVEREEMLRERGLDVTFVKT 60 Query: 364 DVRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVGTY 534 DV ++ ++ TVE +G +D+LVN AA + S + + + V+ ++ G Y Sbjct: 61 DVADENSVKNMVRKTVEIYGGVDVLVNNAAVMSVKSIFERPLEEWERVIRVNLTGPY 117
>BAIA1_EUBSP (P07914) Bile acid 7-dehydroxylase 1/3 (EC 1.17.1.6) (Cholate| 7-alpha-dehydroxylase 1/3) (Bile acid-inducible protein 1/3) Length = 249 Score = 58.5 bits (140), Expect = 1e-08 Identities = 31/125 (24%), Positives = 65/125 (52%), Gaps = 2/125 (1%) Frame = +1 Query: 184 VLRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRS--EGLRAVGF 357 +++ K +ITGG GI F A +GA V+I G +E +D A+A L+ +GF Sbjct: 3 LVQDKITIITGGTRGIGFAAAKLFIENGAKVSIFGETQEEVDTALAQLKELYPEEEVLGF 62 Query: 358 QGDVRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVGTYT 537 D+ +++ + + + +G+LD+++N A + ++ + F+ +++I+ G + Sbjct: 63 APDLTSRDAVMAAVGTVAQKYGRLDVMINNAGITMNSVFSRVSEEDFKNIMDINVNGVFN 122 Query: 538 MCYEA 552 + A Sbjct: 123 GAWSA 127
>DHG_BACME (P40288) Glucose 1-dehydrogenase (EC 1.1.1.47)| Length = 261 Score = 58.2 bits (139), Expect = 2e-08 Identities = 32/124 (25%), Positives = 62/124 (50%), Gaps = 1/124 (0%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRRE-VLDKAVAALRSEGLRAVGFQG 363 L GK +ITG +G+ +A + A A V + R +E + + ++ G A+ +G Sbjct: 5 LEGKVVVITGSSTGLGKSMAIRFATEKAKVVVNYRSKEDEANSVLEEIKKVGGEAIAVKG 64 Query: 364 DVRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVGTYTMC 543 DV + D ++ S ++ FGKLD+++N A S +++ + V++ + G + Sbjct: 65 DVTVESDVINLVQSAIKEFGKLDVMINNAGLENPVSSHEMSLSDWNKVIDTNLTGAFLGS 124 Query: 544 YEAL 555 EA+ Sbjct: 125 REAI 128
>TRN2_DATST (P50163) Tropinone reductase 2 (EC 1.1.1.236) (Tropinone| reductase-II) (TR-II) Length = 260 Score = 58.2 bits (139), Expect = 2e-08 Identities = 35/117 (29%), Positives = 58/117 (49%), Gaps = 1/117 (0%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGD 366 L G AL+TGG GI + I +LA GA V R ++ L+ + RS+G + D Sbjct: 7 LEGCTALVTGGSRGIGYGIVEELASLGASVYTCSRNQKELNDCLTQWRSKGFKVEASVCD 66 Query: 367 VRNQEDAARVLASTVEHF-GKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVGTY 534 + ++ + ++ + HF GKL+ILVN A +D T + + ++ I+ Y Sbjct: 67 LSSRSERQELMNTVANHFHGKLNILVNNAGIVIYKEAKDYTVEDYSLIMSINFEAAY 123
>UCPA_SALTY (P0A2D1) Oxidoreductase ucpA (EC 1.-.-.-)| Length = 263 Score = 57.8 bits (138), Expect = 2e-08 Identities = 39/102 (38%), Positives = 51/102 (50%), Gaps = 4/102 (3%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGD 366 L GK ALITG GI IA ARHGA++ ++ E+ +K L G R + D Sbjct: 4 LTGKTALITGASQGIGEGIARVFARHGANLILLDISDEI-EKLADELGGRGHRCTAVKAD 62 Query: 367 VRNQEDAARVLASTVEHFGKLDILVNGAA----GNFLASPED 480 VR+ +A E G++DILVN A GNFL E+ Sbjct: 63 VRDFASVQAAVARAKETEGRIDILVNNAGVCRLGNFLDMSEE 104
>UCPA_SALTI (P0A2D2) Oxidoreductase ucpA (EC 1.-.-.-)| Length = 263 Score = 57.8 bits (138), Expect = 2e-08 Identities = 39/102 (38%), Positives = 51/102 (50%), Gaps = 4/102 (3%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGD 366 L GK ALITG GI IA ARHGA++ ++ E+ +K L G R + D Sbjct: 4 LTGKTALITGASQGIGEGIARVFARHGANLILLDISDEI-EKLADELGGRGHRCTAVKAD 62 Query: 367 VRNQEDAARVLASTVEHFGKLDILVNGAA----GNFLASPED 480 VR+ +A E G++DILVN A GNFL E+ Sbjct: 63 VRDFASVQAAVARAKETEGRIDILVNNAGVCRLGNFLDMSEE 104
>DHI1_SHEEP (P51975) Corticosteroid 11-beta-dehydrogenase isozyme 1 (EC| 1.1.1.146) (11-DH) (11-beta-hydroxysteroid dehydrogenase 1) (11-beta-HSD1) Length = 291 Score = 57.4 bits (137), Expect = 3e-08 Identities = 34/91 (37%), Positives = 48/91 (52%), Gaps = 1/91 (1%) Frame = +1 Query: 172 FRADVLRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAV 351 FR ++LRGK ++TG GI E+A LAR GAHV + R E L K V+ G + Sbjct: 26 FRPEMLRGKRVIVTGASKGIGREMAYHLARMGAHVVVTARSEESLKKVVSRCLELGAASA 85 Query: 352 GF-QGDVRNQEDAARVLASTVEHFGKLDILV 441 + G + N A + +A E G LD+L+ Sbjct: 86 HYVAGTMENMTFAEQFVAKAGELVGGLDMLI 116
>FABG_BACSU (P51831) 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100)| (3-ketoacyl-acyl carrier protein reductase) Length = 246 Score = 57.0 bits (136), Expect = 4e-08 Identities = 32/90 (35%), Positives = 49/90 (54%), Gaps = 1/90 (1%) Frame = +1 Query: 184 VLRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREV-LDKAVAALRSEGLRAVGFQ 360 +L K A++TG GI IA LA+ GA+V + E ++ V ++S G +A+ + Sbjct: 1 MLNDKTAIVTGASRGIGRSIALDLAKSGANVVVNYSGNEAKANEVVDEIKSMGRKAIAVK 60 Query: 361 GDVRNQEDAARVLASTVEHFGKLDILVNGA 450 DV N ED ++ T+ F +DILVN A Sbjct: 61 ADVSNPEDVQNMIKETLSVFSTIDILVNNA 90
>DHKR_STRCM (P41177) Monensin polyketide synthase putative ketoacyl reductase| (EC 1.3.1.-) (ORF5) Length = 261 Score = 56.6 bits (135), Expect = 5e-08 Identities = 38/116 (32%), Positives = 60/116 (51%), Gaps = 1/116 (0%) Frame = +1 Query: 196 KAALITGGGSGICFEIAAQLARHGAHVAIMGRRREV-LDKAVAALRSEGLRAVGFQGDVR 372 + AL+TG SGI A LA G H+ +G R E + V ALR++GL A G DVR Sbjct: 7 RVALVTGATSGIGLATARLLAAQG-HLVFLGARTESDVIATVKALRNDGLEAEGQVLDVR 65 Query: 373 NQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVGTYTM 540 + + + V+ +G++D+LVN A + DLT + + V++ + + M Sbjct: 66 DGASVTAFVQAAVDRYGRIDVLVNNAGRSGGGVTADLTDELWDDVIDTNLNSVFRM 121
>Y048_HAEIN (P44481) Putative oxidoreductase HI0048 (EC 1.-.-.-)| Length = 285 Score = 56.6 bits (135), Expect = 5e-08 Identities = 38/123 (30%), Positives = 56/123 (45%), Gaps = 9/123 (7%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGD 366 L K +ITG G +C +A QLA A++A++ E DK + G +A ++ + Sbjct: 13 LENKLIIITGAGGVLCSFLAKQLAYTKANIALLDLNFEAADKVAKEINQSGGKAKAYKTN 72 Query: 367 VRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGF---------RTVLEID 519 V E+ V FG DIL+NGA GN +P+ T F RT ++D Sbjct: 73 VLELENIKEVRNQIETDFGTCDILINGAGGN---NPKATTDNEFHQFDLNETTRTFFDLD 129 Query: 520 TVG 528 G Sbjct: 130 KSG 132
>BPHB_COMTE (Q46381) Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase (EC| 1.3.1.56) (Biphenyl-2,3-dihydro-2,3-diol dehydrogenase) (2,3-dihydro-2,3-dihydroxybiphenyl dehydrogenase) (Biphenyl-cis-diol dehydrogenase) (2,3-dihydroxy-4-phenylhexa-4,6-diene dehyd Length = 281 Score = 56.6 bits (135), Expect = 5e-08 Identities = 40/119 (33%), Positives = 56/119 (47%), Gaps = 5/119 (4%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGD 366 L G+ ALITGG SG+ + + GA VA++ + E L + A G AVG GD Sbjct: 3 LTGEVALITGGASGLGRALVDRFVAEGARVAVLDKSAERLRELEVA---HGGNAVGVVGD 59 Query: 367 VRNQEDAARVLASTVEHFGKLDILVNGAA----GNFLAS-PEDLTPKGFRTVLEIDTVG 528 VR+ +D R + FGK+D L+ A LA PED F + ++ G Sbjct: 60 VRSLQDQKRAAERCLAAFGKIDTLIPNAGIWDYSTALADLPEDKIDAAFDDIFHVNVKG 118
>DHGA_BACME (P10528) Glucose 1-dehydrogenase A (EC 1.1.1.47)| Length = 261 Score = 56.2 bits (134), Expect = 6e-08 Identities = 34/125 (27%), Positives = 61/125 (48%), Gaps = 2/125 (1%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAI--MGRRREVLDKAVAALRSEGLRAVGFQ 360 L+ K +ITGG +G+ +A + + A V I E LD A + G +A+ Q Sbjct: 5 LKDKVVVITGGSTGLGRAMAVRFGQEEAKVVINYYNNEEEALD-AKKEVEEAGGQAIIVQ 63 Query: 361 GDVRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVGTYTM 540 GDV +ED ++ + ++ FG LD+++N A +L+ + V++ + G + Sbjct: 64 GDVTKEEDVVNLVQTAIKEFGTLDVMINNAGVENPVPSHELSLDNWNKVIDTNLTGAFLG 123 Query: 541 CYEAL 555 EA+ Sbjct: 124 SREAI 128
>DHG4_BACME (P39485) Glucose 1-dehydrogenase 4 (EC 1.1.1.47) (GLCDH-IV)| Length = 261 Score = 56.2 bits (134), Expect = 6e-08 Identities = 34/125 (27%), Positives = 61/125 (48%), Gaps = 2/125 (1%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAI--MGRRREVLDKAVAALRSEGLRAVGFQ 360 L+ K +ITGG +G+ +A + + A V I E LD A + G +A+ Q Sbjct: 5 LKDKVVVITGGSTGLGRAMAVRFGQEEAKVVINYYNNEEEALD-AKKEVEEAGGQAIIVQ 63 Query: 361 GDVRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVGTYTM 540 GDV +ED ++ + ++ FG LD+++N A +L+ + V++ + G + Sbjct: 64 GDVTKEEDVVNLVQTAIKEFGTLDVMINNAGVENPVPSHELSLDNWNKVIDTNLTGAFLG 123 Query: 541 CYEAL 555 EA+ Sbjct: 124 SREAI 128
>DHG3_BACME (P39484) Glucose 1-dehydrogenase 3 (EC 1.1.1.47) (GLCDH-III)| Length = 261 Score = 56.2 bits (134), Expect = 6e-08 Identities = 34/125 (27%), Positives = 61/125 (48%), Gaps = 2/125 (1%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAI--MGRRREVLDKAVAALRSEGLRAVGFQ 360 L+ K +ITGG +G+ +A + + A V I E LD A + G +A+ Q Sbjct: 5 LKDKVVVITGGSTGLGRAMAVRFGQEEAKVVINYYNNEEEALD-AKKEVEEAGGQAIIVQ 63 Query: 361 GDVRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVGTYTM 540 GDV +ED ++ + ++ FG LD+++N A +L+ + V++ + G + Sbjct: 64 GDVTKEEDVVNLVQTAIKEFGTLDVMINNAGVENPVPSHELSLDNWNKVIDTNLTGAFLG 123 Query: 541 CYEAL 555 EA+ Sbjct: 124 SREAI 128
>DHK1_STRVN (P16542) Granaticin polyketide synthase putative ketoacyl reductase| 1 (EC 1.3.1.-) (ORF5) Length = 272 Score = 56.2 bits (134), Expect = 6e-08 Identities = 37/118 (31%), Positives = 56/118 (47%) Frame = +1 Query: 202 ALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGDVRNQE 381 AL+TG SGI IA +LA GA + R E L + V LR EG G DV + Sbjct: 20 ALVTGATSGIGLAIARRLAALGARTFLCARDEERLAQTVKELRGEGFDVDGTVCDVADPA 79 Query: 382 DAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVGTYTMCYEAL 555 +A+ V+ +G +DILVN A + + ++ + + V+ + + M E L Sbjct: 80 QIRAYVAAAVQRYGTVDILVNNAGRSGGGATAEIADELWLDVITTNLTSVFLMTKEVL 137
>HSD_STREX (P19992) 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase (EC| 1.1.1.53) Length = 255 Score = 55.8 bits (133), Expect = 8e-08 Identities = 46/120 (38%), Positives = 61/120 (50%), Gaps = 4/120 (3%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQG- 363 L GK +ITGG G+ E A Q GA V + +VLD+ AA E A +Q Sbjct: 4 LSGKTVIITGGARGLGAEAARQAVAAGARVVLA----DVLDEEGAATARELGDAARYQHL 59 Query: 364 DVRNQEDAARVLASTVEHFGKLDILVNGA---AGNFLASPEDLTPKGFRTVLEIDTVGTY 534 DV +ED RV+A E FG +D LVN A G FL E + + FR V++I+ G + Sbjct: 60 DVTIEEDWQRVVAYAREEFGSVDGLVNNAGISTGMFL---ETESVERFRKVVDINLTGVF 116
>DHI1_CAVPO (Q6QLL4) Corticosteroid 11-beta-dehydrogenase isozyme 1 (EC| 1.1.1.146) (11-DH) (11-beta-hydroxysteroid dehydrogenase 1) (11-beta-HSD1) Length = 299 Score = 55.5 bits (132), Expect = 1e-07 Identities = 32/91 (35%), Positives = 47/91 (51%), Gaps = 1/91 (1%) Frame = +1 Query: 172 FRADVLRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAV 351 FR ++L+GK ++TG GI EIA LA+ GAHV + R +E L K VA G + Sbjct: 26 FRPEMLQGKKVIVTGASKGIGREIAYHLAKMGAHVVVTARSKEALQKVVARCLELGAASA 85 Query: 352 GF-QGDVRNQEDAARVLASTVEHFGKLDILV 441 + G + + A +A G LD+L+ Sbjct: 86 HYIAGSMEDMTFAEEFVAEAGNLMGGLDMLI 116
>BPHB_BURCE (P47227) Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase (EC| 1.3.1.56) (Biphenyl-2,3-dihydro-2,3-diol dehydrogenase) (2,3-dihydro-2,3-dihydroxybiphenyl dehydrogenase) (Biphenyl-cis-diol dehydrogenase) (2,3-dihydroxy-4-phenylhexa-4,6-diene dehyd Length = 277 Score = 55.1 bits (131), Expect = 1e-07 Identities = 39/120 (32%), Positives = 59/120 (49%), Gaps = 6/120 (5%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSE-GLRAVGFQG 363 L+G+A LITGG SG+ + + GA VA++ + E L A L ++ G +G G Sbjct: 3 LKGEAVLITGGASGLGRALVDRFVAEGAKVAVLDKSAERL----AELETDHGDNVLGIVG 58 Query: 364 DVRNQEDAARVLASTVEHFGKLDILVNGA-----AGNFLASPEDLTPKGFRTVLEIDTVG 528 DVR+ ED + + V FGK+D L+ A + + PE+ F V I+ G Sbjct: 59 DVRSLEDQKQAASRCVARFGKIDTLIPNAGIWDYSTALVDLPEESLDAAFDEVFHINVKG 118
>DHSO_RHOSH (Q59787) Sorbitol dehydrogenase (EC 1.1.1.14) (L-iditol| 2-dehydrogenase) (Polyol dehydrogenase) Length = 256 Score = 55.1 bits (131), Expect = 1e-07 Identities = 42/118 (35%), Positives = 55/118 (46%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGD 366 L GK ALITG GI A R GA VAI L+ A A G A D Sbjct: 3 LDGKTALITGSARGIGRAFAEAYVREGARVAIADIN---LEAARATAAEIGPAACAIALD 59 Query: 367 VRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVGTYTM 540 V +Q R +A ++ +G +DILVN AA LA ++T + + + I+ GT M Sbjct: 60 VTDQASIDRCVAELLDRWGSIDILVNNAALFDLAPIVEITRESYDRLFAINVSGTLFM 117
>LINC_PSEPA (P50197) 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase (EC| 1.1.1.-) (2,5-DDOL dehydrogenase) Length = 250 Score = 55.1 bits (131), Expect = 1e-07 Identities = 41/125 (32%), Positives = 63/125 (50%), Gaps = 2/125 (1%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGD 366 L GK ++TGGGSGI L GA+V + E + VA + G +A F+ D Sbjct: 4 LSGKTIIVTGGGSGIGRATVELLVASGANVPVADINDEAGEAVVA---TSGGKAAYFRCD 60 Query: 367 VRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASP-EDLTPKGFRTVLEIDTVGTY-TM 540 + +ED ++A T+ FG LD N AA P +++ + FR ++I+ GT+ M Sbjct: 61 IAQEEDVKALVAQTLAAFGGLDGSFNNAAIPQAGLPLAEVSLERFRQSMDINVTGTFLCM 120 Query: 541 CYEAL 555 Y+ L Sbjct: 121 KYQIL 125
>UCPA_ECOLI (P37440) Oxidoreductase ucpA (EC 1.-.-.-)| Length = 263 Score = 55.1 bits (131), Expect = 1e-07 Identities = 38/102 (37%), Positives = 50/102 (49%), Gaps = 4/102 (3%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGD 366 L GK ALITG GI IA ARHGA++ ++ E+ +K L G R D Sbjct: 4 LTGKTALITGALQGIGEGIARTFARHGANLILLDISPEI-EKLADELCGRGHRCTAVVAD 62 Query: 367 VRNQEDAARVLASTVEHFGKLDILVNGAA----GNFLASPED 480 VR+ A + E G++DILVN A G+FL +D Sbjct: 63 VRDPASVAAAIKRAKEKEGRIDILVNNAGVCRLGSFLDMSDD 104
>UCPA_ECO57 (Q8XBJ4) Oxidoreductase ucpA (EC 1.-.-.-)| Length = 263 Score = 55.1 bits (131), Expect = 1e-07 Identities = 38/102 (37%), Positives = 50/102 (49%), Gaps = 4/102 (3%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGD 366 L GK ALITG GI IA ARHGA++ ++ E+ +K L G R D Sbjct: 4 LTGKTALITGALQGIGEGIARTFARHGANLILLDISPEI-EKLADELCGRGHRCTAVVAD 62 Query: 367 VRNQEDAARVLASTVEHFGKLDILVNGAA----GNFLASPED 480 VR+ A + E G++DILVN A G+FL +D Sbjct: 63 VRDPASVAAAIKRAKEKEGRIDILVNNAGVCRLGSFLDMSDD 104
>PGDH_MACFA (Q8MJY8) 15-hydroxyprostaglandin dehydrogenase [NAD+] (EC| 1.1.1.141) (PGDH) (Prostaglandin dehydrogenase 1) Length = 266 Score = 54.7 bits (130), Expect = 2e-07 Identities = 41/125 (32%), Positives = 57/125 (45%), Gaps = 2/125 (1%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAAL--RSEGLRAVGFQ 360 + GK AL+TG GI A L GA VA++ E + AAL + E + + Q Sbjct: 3 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEKFEPQKTLFIQ 62 Query: 361 GDVRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVGTYTM 540 DV +Q+ V+HFG+LDILVN A N K + L+I+ V + Sbjct: 63 CDVADQQQLRDTFRKVVDHFGRLDILVNNAGVN--------NEKNWEKTLQINLVSVISG 114 Query: 541 CYEAL 555 Y L Sbjct: 115 TYLGL 119
>BPHB_PSES1 (P50206) Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase (EC| 1.3.1.56) (Biphenyl-2,3-dihydro-2,3-diol dehydrogenase) (2,3-dihydro-2,3-dihydroxybiphenyl dehydrogenase) (Biphenyl-cis-diol dehydrogenase) (2,3-dihydroxy-4-phenylhexa-4,6-diene dehyd Length = 276 Score = 54.7 bits (130), Expect = 2e-07 Identities = 40/123 (32%), Positives = 57/123 (46%), Gaps = 9/123 (7%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALR----SEGLRAVG 354 L + AL+TGGGSG+ I + GA VA VLDK+ A L+ + G + +G Sbjct: 3 LNNEVALVTGGGSGLGRAIVDRFVAEGARVA-------VLDKSAARLQELQAAHGAKVLG 55 Query: 355 FQGDVRNQEDAARVLASTVEHFGKLDILVNGA-----AGNFLASPEDLTPKGFRTVLEID 519 +GDVR D + V FGK+D L+ A + + P+D F V I+ Sbjct: 56 IEGDVRVLADHQKAARECVAAFGKIDCLIPNAGIWDYSMPLVDIPDDRIDAAFDEVFHIN 115 Query: 520 TVG 528 G Sbjct: 116 VKG 118
>BAIA2_EUBSP (P19337) Bile acid 7-dehydroxylase 2 (EC 1.17.1.6) (Cholate| 7-alpha-dehydroxylase 2) (Bile acid-inducible protein 2) Length = 249 Score = 54.7 bits (130), Expect = 2e-07 Identities = 30/120 (25%), Positives = 62/120 (51%), Gaps = 2/120 (1%) Frame = +1 Query: 181 DVLRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRS--EGLRAVG 354 ++++ K +ITGG GI F A +GA V+I G +E +D A+A L+ +G Sbjct: 2 NLVQDKVTIITGGTRGIGFAAAKIFIDNGAKVSIFGETQEEVDTALAQLKELYPEEEVLG 61 Query: 355 FQGDVRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVGTY 534 F D+ +++ + + +G+LD+++N A ++ + F+ +++I+ G + Sbjct: 62 FAPDLTSRDAVMAAVGQVAQKYGRLDVMINNAGITSNNVFSRVSEEEFKHIMDINVTGVF 121
>3BHD_COMTE (P19871) 3-beta-hydroxysteroid dehydrogenase (EC 1.1.1.51)| Length = 253 Score = 54.7 bits (130), Expect = 2e-07 Identities = 37/123 (30%), Positives = 58/123 (47%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGD 366 L+GK AL+TGG SG+ E+ L GA VA + A L G R++ + D Sbjct: 4 LQGKVALVTGGASGVGLEVVKLLLGEGAKVAFSDINEAAGQQLAAEL---GERSMFVRHD 60 Query: 367 VRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVGTYTMCY 546 V ++ D V+A+ G L++LVN A E + F +L+I+T + C Sbjct: 61 VSSEADWTLVMAAVQRRLGTLNVLVNNAGILLPGDMETGRLEDFSRLLKINTESVFIGCQ 120 Query: 547 EAL 555 + + Sbjct: 121 QGI 123
>PGDH_HUMAN (P15428) 15-hydroxyprostaglandin dehydrogenase [NAD+] (EC| 1.1.1.141) (PGDH) (Prostaglandin dehydrogenase 1) Length = 266 Score = 54.3 bits (129), Expect = 2e-07 Identities = 41/125 (32%), Positives = 57/125 (45%), Gaps = 2/125 (1%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAAL--RSEGLRAVGFQ 360 + GK AL+TG GI A L GA VA++ E + AAL + E + + Q Sbjct: 3 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQ 62 Query: 361 GDVRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVGTYTM 540 DV +Q+ V+HFG+LDILVN A N K + L+I+ V + Sbjct: 63 CDVADQQQLRDTFRKVVDHFGRLDILVNNAGVN--------NEKNWEKTLQINLVSVISG 114 Query: 541 CYEAL 555 Y L Sbjct: 115 TYLGL 119
>Y1385_MYCBO (P66782) Putative oxidoreductase Mb1385 (EC 1.-.-.-)| Length = 247 Score = 54.3 bits (129), Expect = 2e-07 Identities = 34/119 (28%), Positives = 57/119 (47%) Frame = +1 Query: 178 ADVLRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGF 357 A +L + A+ITGG G+ I + GA V + E + A L + + A+ Sbjct: 2 ASLLNARTAVITGGAQGLGLAIGQRFVAEGARVVLGDVNLEATEVAAKRLGGDDV-ALAV 60 Query: 358 QGDVRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVGTY 534 + DV +D ++ + VE FG LD++VN A A+ +T + F V+ + GT+ Sbjct: 61 RCDVTQADDVDILIRTAVERFGGLDVMVNNAGITRDATMRTMTEEQFDQVIAVHLKGTW 119
>Y1350_MYCTU (P66781) Putative oxidoreductase Rv1350/MT1393 (EC 1.-.-.-)| Length = 247 Score = 54.3 bits (129), Expect = 2e-07 Identities = 34/119 (28%), Positives = 57/119 (47%) Frame = +1 Query: 178 ADVLRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGF 357 A +L + A+ITGG G+ I + GA V + E + A L + + A+ Sbjct: 2 ASLLNARTAVITGGAQGLGLAIGQRFVAEGARVVLGDVNLEATEVAAKRLGGDDV-ALAV 60 Query: 358 QGDVRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVGTY 534 + DV +D ++ + VE FG LD++VN A A+ +T + F V+ + GT+ Sbjct: 61 RCDVTQADDVDILIRTAVERFGGLDVMVNNAGITRDATMRTMTEEQFDQVIAVHLKGTW 119
>FABG_STAAW (P0A0I0) 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100)| (3-ketoacyl-acyl carrier protein reductase) Length = 246 Score = 54.3 bits (129), Expect = 2e-07 Identities = 29/86 (33%), Positives = 48/86 (55%), Gaps = 1/86 (1%) Frame = +1 Query: 196 KAALITGGGSGICFEIAAQLARHGAHVAI-MGRRREVLDKAVAALRSEGLRAVGFQGDVR 372 K+AL+TG GI IA QLA G +VA+ +E + V ++++G+ + Q +V Sbjct: 5 KSALVTGASRGIGRSIALQLAEEGYNVAVNYAGSKEKAEAVVEEIKAKGVDSFAIQANVA 64 Query: 373 NQEDAARVLASTVEHFGKLDILVNGA 450 + ++ ++ V FG LD+LVN A Sbjct: 65 DADEVKAMIKEVVSQFGSLDVLVNNA 90
>FABG_STAAS (Q6G9Y2) 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100)| (3-ketoacyl-acyl carrier protein reductase) Length = 246 Score = 54.3 bits (129), Expect = 2e-07 Identities = 29/86 (33%), Positives = 48/86 (55%), Gaps = 1/86 (1%) Frame = +1 Query: 196 KAALITGGGSGICFEIAAQLARHGAHVAI-MGRRREVLDKAVAALRSEGLRAVGFQGDVR 372 K+AL+TG GI IA QLA G +VA+ +E + V ++++G+ + Q +V Sbjct: 5 KSALVTGASRGIGRSIALQLAEEGYNVAVNYAGSKEKAEAVVEEIKAKGVDSFAIQANVA 64 Query: 373 NQEDAARVLASTVEHFGKLDILVNGA 450 + ++ ++ V FG LD+LVN A Sbjct: 65 DADEVKAMIKEVVSQFGSLDVLVNNA 90
>FABG_STAAR (Q6GHK4) 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100)| (3-ketoacyl-acyl carrier protein reductase) Length = 246 Score = 54.3 bits (129), Expect = 2e-07 Identities = 29/86 (33%), Positives = 48/86 (55%), Gaps = 1/86 (1%) Frame = +1 Query: 196 KAALITGGGSGICFEIAAQLARHGAHVAI-MGRRREVLDKAVAALRSEGLRAVGFQGDVR 372 K+AL+TG GI IA QLA G +VA+ +E + V ++++G+ + Q +V Sbjct: 5 KSALVTGASRGIGRSIALQLAEEGYNVAVNYAGSKEKAEAVVEEIKAKGVDSFAIQANVA 64 Query: 373 NQEDAARVLASTVEHFGKLDILVNGA 450 + ++ ++ V FG LD+LVN A Sbjct: 65 DADEVKAMIKEVVSQFGSLDVLVNNA 90
>FABG_STAAN (P99093) 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100)| (3-ketoacyl-acyl carrier protein reductase) Length = 246 Score = 54.3 bits (129), Expect = 2e-07 Identities = 29/86 (33%), Positives = 48/86 (55%), Gaps = 1/86 (1%) Frame = +1 Query: 196 KAALITGGGSGICFEIAAQLARHGAHVAI-MGRRREVLDKAVAALRSEGLRAVGFQGDVR 372 K+AL+TG GI IA QLA G +VA+ +E + V ++++G+ + Q +V Sbjct: 5 KSALVTGASRGIGRSIALQLAEEGYNVAVNYAGSKEKAEAVVEEIKAKGVDSFAIQANVA 64 Query: 373 NQEDAARVLASTVEHFGKLDILVNGA 450 + ++ ++ V FG LD+LVN A Sbjct: 65 DADEVKAMIKEVVSQFGSLDVLVNNA 90
>FABG_STAAM (P0A0H9) 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100)| (3-ketoacyl-acyl carrier protein reductase) Length = 246 Score = 54.3 bits (129), Expect = 2e-07 Identities = 29/86 (33%), Positives = 48/86 (55%), Gaps = 1/86 (1%) Frame = +1 Query: 196 KAALITGGGSGICFEIAAQLARHGAHVAI-MGRRREVLDKAVAALRSEGLRAVGFQGDVR 372 K+AL+TG GI IA QLA G +VA+ +E + V ++++G+ + Q +V Sbjct: 5 KSALVTGASRGIGRSIALQLAEEGYNVAVNYAGSKEKAEAVVEEIKAKGVDSFAIQANVA 64 Query: 373 NQEDAARVLASTVEHFGKLDILVNGA 450 + ++ ++ V FG LD+LVN A Sbjct: 65 DADEVKAMIKEVVSQFGSLDVLVNNA 90
>FABG_STAAC (Q5HGK2) 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100)| (3-ketoacyl-acyl carrier protein reductase) Length = 246 Score = 54.3 bits (129), Expect = 2e-07 Identities = 29/86 (33%), Positives = 48/86 (55%), Gaps = 1/86 (1%) Frame = +1 Query: 196 KAALITGGGSGICFEIAAQLARHGAHVAI-MGRRREVLDKAVAALRSEGLRAVGFQGDVR 372 K+AL+TG GI IA QLA G +VA+ +E + V ++++G+ + Q +V Sbjct: 5 KSALVTGASRGIGRSIALQLAEEGYNVAVNYAGSKEKAEAVVEEIKAKGVDSFAIQANVA 64 Query: 373 NQEDAARVLASTVEHFGKLDILVNGA 450 + ++ ++ V FG LD+LVN A Sbjct: 65 DADEVKAMIKEVVSQFGSLDVLVNNA 90
>DHI1_RABIT (Q7M3I4) Corticosteroid 11-beta-dehydrogenase isozyme 1 (EC| 1.1.1.146) (11-DH) (11-beta-hydroxysteroid dehydrogenase 1) (11-beta-HSD1) Length = 291 Score = 53.9 bits (128), Expect = 3e-07 Identities = 32/91 (35%), Positives = 49/91 (53%), Gaps = 1/91 (1%) Frame = +1 Query: 172 FRADVLRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVA-ALRSEGLRA 348 FR ++L+GK ++TG GI EIA LA+ GAHV + R +E L + VA L+ A Sbjct: 26 FRPEMLQGKKVIVTGASKGIGKEIAFHLAKMGAHVVVTARSKETLQEVVAHCLKLGAASA 85 Query: 349 VGFQGDVRNQEDAARVLASTVEHFGKLDILV 441 G + + A + +A + G LD+L+ Sbjct: 86 HYIAGTMEDMTFAEQFVAKAGKLMGGLDMLI 116
>BUTA_STAEQ (Q5HKG6) Acetoin(diacetyl) reductase (EC 1.1.1.5) (Acetoin| dehydrogenase) (AR) (Meso-2,3-butanediol dehydrogenase) Length = 257 Score = 53.5 bits (127), Expect = 4e-07 Identities = 29/112 (25%), Positives = 56/112 (50%) Frame = +1 Query: 196 KAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGDVRN 375 K A+ITG G+ IA +LA G ++ + +L + + +G +AV F+ DV Sbjct: 3 KTAIITGSAGGLGKGIAERLANDGFNIVLQDINEALLLETEKEFKEKGYQAVAFKSDVSK 62 Query: 376 QEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVGT 531 +++ ++ V FG+LD++VN A + + ++ + + I+ GT Sbjct: 63 KKEQEELVQFAVTEFGQLDVMVNNAGVDAVTPILEIGEEELSKLFNINVFGT 114
>DHI1_HUMAN (P28845) Corticosteroid 11-beta-dehydrogenase isozyme 1 (EC| 1.1.1.146) (11-DH) (11-beta-hydroxysteroid dehydrogenase 1) (11-beta-HSD1) Length = 291 Score = 53.1 bits (126), Expect = 5e-07 Identities = 30/91 (32%), Positives = 49/91 (53%), Gaps = 1/91 (1%) Frame = +1 Query: 172 FRADVLRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAV 351 FR ++L+GK ++TG GI E+A LA+ GAHV + R +E L K V+ G + Sbjct: 26 FRPEMLQGKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASA 85 Query: 352 GF-QGDVRNQEDAARVLASTVEHFGKLDILV 441 + G + + A + +A + G LD+L+ Sbjct: 86 HYIAGTMEDMTFAEQFVAQAGKLMGGLDMLI 116
>XYLL_PSEPU (P23102) 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate| dehydrogenase (EC 1.3.1.25) (Cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate dehydrogenase) (Cis-1,2-dihydroxy-3,4-cyclohexadiene-1-carboxylate dehydrogenase) (2-hydro-1,2-dihydroxyben Length = 269 Score = 53.1 bits (126), Expect = 5e-07 Identities = 32/98 (32%), Positives = 49/98 (50%), Gaps = 3/98 (3%) Frame = +1 Query: 190 RGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRR---EVLDKAVAALRSEGLRAVGFQ 360 +GK A+ITG GI +A ++A G + ++ R E+ D+ V L A Sbjct: 6 QGKVAVITGAAQGIGRRVAERMAAEGGRLLLVDRSELIHELADELVGVAEVLTLTA---- 61 Query: 361 GDVRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASP 474 D+ + RV+A+ +E FG+LDIL+N G A P Sbjct: 62 -DLEQFAECQRVMAAALERFGRLDILINNVGGTIWAKP 98
>YGCW_ECOLI (P76633) Hypothetical oxidoreductase ygcW (EC 1.-.-.-)| Length = 261 Score = 53.1 bits (126), Expect = 5e-07 Identities = 35/128 (27%), Positives = 63/128 (49%), Gaps = 6/128 (4%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAI------MGRRREVLDKAVAALRSEGLRA 348 L+GK A++TGG SG+ A LA+ GA++ I G +E+++K +G+ Sbjct: 16 LKGKTAIVTGGNSGLGQAFAMALAKAGANIFIPSFVKDNGETKEMIEK-------QGVEV 68 Query: 349 VGFQGDVRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVG 528 Q + + +++A+ E FG +DILVN A L D + +++++ Sbjct: 69 DFMQVGITAEGAPQKIIAACCERFGTVDILVNNAGICKLNKVLDFGRADWDPMIDVNLTA 128 Query: 529 TYTMCYEA 552 + + YEA Sbjct: 129 AFELSYEA 136
>DHI1_SAISC (Q29608) Corticosteroid 11-beta-dehydrogenase isozyme 1 (EC| 1.1.1.146) (11-DH) (11-beta-hydroxysteroid dehydrogenase 1) (11-beta-HSD1) Length = 290 Score = 53.1 bits (126), Expect = 5e-07 Identities = 30/91 (32%), Positives = 49/91 (53%), Gaps = 1/91 (1%) Frame = +1 Query: 172 FRADVLRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAV 351 FR ++L+GK ++TG GI E+A LA+ GAHV + R +E L K V+ G + Sbjct: 26 FRPEMLQGKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASA 85 Query: 352 GF-QGDVRNQEDAARVLASTVEHFGKLDILV 441 + G + + A + +A + G LD+L+ Sbjct: 86 HYIAGTMEDMTFAEQFVAQAGKLMGGLDMLI 116
>YHXC_BACSU (P40397) Hypothetical oxidoreductase yhxC (EC 1.-.-.-) (ORFX)| Length = 285 Score = 53.1 bits (126), Expect = 5e-07 Identities = 32/98 (32%), Positives = 52/98 (53%), Gaps = 1/98 (1%) Frame = +1 Query: 163 ESPFRADVLRGKAALITGGGSGICFEIAAQLARHGAHVAIMG-RRREVLDKAVAALRSEG 339 + P +A L GK A+ITGG SGI ++ A+ GA+V I+ + ++ + EG Sbjct: 31 DKPKKAKKLEGKTAIITGGDSGIGRAVSVLFAKEGANVVIVYLNEHQDAEETKQYVEKEG 90 Query: 340 LRAVGFQGDVRNQEDAARVLASTVEHFGKLDILVNGAA 453 ++ + GDV ++ V+ + F +DILVN AA Sbjct: 91 VKCLLIAGDVGDEAFCNDVVGQASQVFPSIDILVNNAA 128
>SOU2_CANAL (P87218) Sorbitol utilization protein SOU2 (EC 1.1.-.-)| Length = 280 Score = 52.8 bits (125), Expect = 7e-07 Identities = 35/119 (29%), Positives = 59/119 (49%), Gaps = 3/119 (2%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGD 366 L+GK A +TG GI + +A A+ GA VAI DKA ++ G+++ ++ + Sbjct: 33 LKGKVASVTGSSGGIGWAVAEGYAQAGADVAIWYNSHPADDKAEYLTKTYGVKSKAYKCN 92 Query: 367 VRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKG---FRTVLEIDTVGTY 534 V + +D +V+ FG +DI V A + PE + KG + V+++D Y Sbjct: 93 VTDFQDVEKVVKQIESDFGTIDIFVANAGVAWTEGPE-IDVKGVDKWNKVVDVDLNSVY 150
>DHRS3_BOVIN (O77769) Short-chain dehydrogenase/reductase 3 (EC 1.1.-.-)| (Retinal short-chain dehydrogenase/reductase 1) (retSDR1) Length = 302 Score = 52.8 bits (125), Expect = 7e-07 Identities = 39/127 (30%), Positives = 60/127 (47%), Gaps = 5/127 (3%) Frame = +1 Query: 169 PFRADVLRGKAALITGGGSGICFEIAAQLARHGAH-VAIMGRRREVLDKAVAALRSEGLR 345 P + L + LITGGG GI ++A + A GA + + GR + L + +R G Sbjct: 30 PAKLRDLSRENVLITGGGRGIGRQLAREFAERGARKIVLWGRTEKCLKETTEEIRQMGTE 89 Query: 346 AVGFQGDVRNQEDAARVLASTVEHFGKLDILVNGAA----GNFLASPEDLTPKGFRTVLE 513 F DV N+E+ + + E G + ILVN AA + + S +D PK Sbjct: 90 CHYFICDVGNREEVYQTAKAVREKVGDITILVNNAAVVHGKSLMDSDDDALPKS----QH 145 Query: 514 IDTVGTY 534 I+T+G + Sbjct: 146 INTLGQF 152
>BUTA_STAES (Q8CQD2) Acetoin(diacetyl) reductase (EC 1.1.1.5) (Acetoin| dehydrogenase) (AR) (Meso-2,3-butanediol dehydrogenase) Length = 257 Score = 52.4 bits (124), Expect = 9e-07 Identities = 28/112 (25%), Positives = 56/112 (50%) Frame = +1 Query: 196 KAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGDVRN 375 K A+ITG G+ IA +LA G ++ + +L + + +G +AV ++ DV Sbjct: 3 KTAIITGAAGGLGKGIAERLANDGFNIVLQDINEALLLETEKEFKEKGYQAVAYKSDVSK 62 Query: 376 QEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVGT 531 +++ ++ V FG+LD++VN A + + ++ + + I+ GT Sbjct: 63 KKEQEELVQFAVTEFGQLDVMVNNAGVDAVTPILEIGEEELSKLFNINVFGT 114
>DHG2_BACME (P39483) Glucose 1-dehydrogenase 2 (EC 1.1.1.47) (GLCDH-II)| Length = 261 Score = 52.4 bits (124), Expect = 9e-07 Identities = 30/124 (24%), Positives = 60/124 (48%), Gaps = 1/124 (0%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAA-LRSEGLRAVGFQG 363 L+ K ++TGG G+ +A + + + V + R E V + G +A+ +G Sbjct: 5 LKDKVVVVTGGSKGLGRAMAVRFGQEQSKVVVNYRSNEEEALEVKKEIEEAGGQAIIVRG 64 Query: 364 DVRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVGTYTMC 543 DV +ED ++ + V+ FG LD+++N A +L+ + + V++ + G + Sbjct: 65 DVTKEEDVVNLVETAVKEFGSLDVMINNAGVENPVPSHELSLENWNQVIDTNLTGAFLGS 124 Query: 544 YEAL 555 EA+ Sbjct: 125 REAI 128
>FABG_STAES (Q8CPI3) 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100)| (3-ketoacyl-acyl carrier protein reductase) Length = 244 Score = 52.4 bits (124), Expect = 9e-07 Identities = 27/86 (31%), Positives = 47/86 (54%), Gaps = 1/86 (1%) Frame = +1 Query: 196 KAALITGGGSGICFEIAAQLARHGAHVAI-MGRRREVLDKAVAALRSEGLRAVGFQGDVR 372 K+AL+TG GI IA QLA G +VA+ ++ + V ++++G+ + Q +V Sbjct: 3 KSALVTGASRGIGRSIALQLAEEGYNVAVNYAGSKDKAEAVVEEIKAKGVESFAIQANVA 62 Query: 373 NQEDAARVLASTVEHFGKLDILVNGA 450 ++ ++ V FG +D+LVN A Sbjct: 63 KGDEVKEMIKEVVSQFGSVDVLVNNA 88
>FABG_STAEQ (Q5HPW0) 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100)| (3-ketoacyl-acyl carrier protein reductase) Length = 244 Score = 52.4 bits (124), Expect = 9e-07 Identities = 27/86 (31%), Positives = 47/86 (54%), Gaps = 1/86 (1%) Frame = +1 Query: 196 KAALITGGGSGICFEIAAQLARHGAHVAI-MGRRREVLDKAVAALRSEGLRAVGFQGDVR 372 K+AL+TG GI IA QLA G +VA+ ++ + V ++++G+ + Q +V Sbjct: 3 KSALVTGASRGIGRSIALQLAEEGYNVAVNYAGSKDKAEAVVEEIKAKGVESFAIQANVA 62 Query: 373 NQEDAARVLASTVEHFGKLDILVNGA 450 ++ ++ V FG +D+LVN A Sbjct: 63 KGDEVKEMIKEVVSQFGSVDVLVNNA 88
>Y4LA_RHISN (P55541) Putative short-chain type dehydrogenase/reductase y4lA (EC| 1.-.-.-) Length = 278 Score = 52.4 bits (124), Expect = 9e-07 Identities = 33/109 (30%), Positives = 52/109 (47%) Frame = +1 Query: 193 GKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGDVR 372 GK A++TG G+GI A +AR G V + A + +E A+ D+ Sbjct: 6 GKVAVVTGAGAGIGKACALAIAREGGRVVVADLDGSAAIACTAQIAAEAGNALAMAMDIA 65 Query: 373 NQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEID 519 + + A + + HFG +D+LVN AS LTP+ R +L++D Sbjct: 66 DAQAVAALFETAERHFGGVDLLVNN------ASAMHLTPRD-RAILDLD 107
>SOU1_CANAL (P87219) Sorbitol utilization protein SOU1 (EC 1.1.-.-)| Length = 281 Score = 52.4 bits (124), Expect = 9e-07 Identities = 34/119 (28%), Positives = 59/119 (49%), Gaps = 3/119 (2%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGD 366 L+GK A +TG GI + +A A+ GA VAI + KA G++A ++ + Sbjct: 33 LKGKVASVTGSSGGIGWAVAEAFAQAGADVAIWYNSKPADAKAEYLTEKYGVKAKAYKCN 92 Query: 367 VRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGF---RTVLEIDTVGTY 534 V + D ++V+ + FG +DI V A + PE + +G+ + +++ D G Y Sbjct: 93 VTDPNDVSKVINEIEKDFGTIDIFVANAGVAWTDGPE-IDVQGYDQWKKIVDCDLNGVY 150
>Y452_LISIN (Q92EK7) Hypothetical oxidoreductase Lin0452 (EC 1.-.-.-)| Length = 248 Score = 52.4 bits (124), Expect = 9e-07 Identities = 27/84 (32%), Positives = 46/84 (54%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGD 366 ++ K +ITG SGI A LA GA + + RR E L+K V +++ A+ + D Sbjct: 3 IKNKVIIITGASSGIGEATAILLAEKGAKLVLAARRVEKLEKIVQTIKASSGEAIFAKTD 62 Query: 367 VRNQEDAARVLASTVEHFGKLDIL 438 V +ED +++ +E +GK+D + Sbjct: 63 VTKREDNKKLVELAIERYGKVDAI 86
>Y432_LISMO (P25145) Hypothetical oxidoreductase Lmo0432 (EC 1.-.-.-) (ORFA)| Length = 248 Score = 52.4 bits (124), Expect = 9e-07 Identities = 27/84 (32%), Positives = 46/84 (54%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGD 366 ++ K +ITG SGI A LA GA + + RR E L+K V +++ A+ + D Sbjct: 3 IKNKVIIITGASSGIGKATALLLAEKGAKLVLAARRVEKLEKIVQTIKANSGEAIFAKTD 62 Query: 367 VRNQEDAARVLASTVEHFGKLDIL 438 V +ED +++ +E +GK+D + Sbjct: 63 VTKREDNKKLVELAIERYGKVDAI 86
>DHI1_RAT (P16232) Corticosteroid 11-beta-dehydrogenase isozyme 1 (EC| 1.1.1.146) (11-DH) (11-beta-hydroxysteroid dehydrogenase 1) (11-beta-HSD1) Length = 288 Score = 52.0 bits (123), Expect = 1e-06 Identities = 30/96 (31%), Positives = 49/96 (51%), Gaps = 1/96 (1%) Frame = +1 Query: 157 ATESPFRADVLRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSE 336 +T FR ++L+GK ++TG GI E+A L++ GAHV + R E L K V+ Sbjct: 18 STNEEFRPEMLQGKKVIVTGASKGIGREMAYHLSKMGAHVVLTARSEEGLQKVVSRCLEL 77 Query: 337 GLRAVGF-QGDVRNQEDAARVLASTVEHFGKLDILV 441 G + + G + + A R + + G LD+L+ Sbjct: 78 GAASAHYIAGTMEDMAFAERFVVEAGKLLGGLDMLI 113
>BACC_BACAM (Q8KWS9) Bacilysin biosynthesis oxidoreductase bacC (EC 1.-.-.-)| Length = 254 Score = 51.6 bits (122), Expect = 1e-06 Identities = 37/126 (29%), Positives = 57/126 (45%), Gaps = 3/126 (2%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAV--AALRSEGLRAVGF- 357 L K LITGG SGI + A+V + +D+A A +R E + F Sbjct: 3 LTDKTVLITGGASGIGYAAVQAFLNQQANVVVAD-----IDEAQGEAMIRKENNDRLHFV 57 Query: 358 QGDVRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVGTYT 537 Q D+ N+ + S V+ FG LD+L+N A +A ++ + VL ++ G + Sbjct: 58 QTDITNEPACQNAILSAVDKFGGLDVLINNAGIEIVAPIHEMELSDWNKVLNVNLTGMFL 117 Query: 538 MCYEAL 555 M AL Sbjct: 118 MSKHAL 123
>DHG_BACSU (P12310) Glucose 1-dehydrogenase (EC 1.1.1.47)| Length = 261 Score = 51.6 bits (122), Expect = 1e-06 Identities = 36/128 (28%), Positives = 59/128 (46%), Gaps = 5/128 (3%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAI-----MGRRREVLDKAVAALRSEGLRAV 351 L+GK ITG SG+ +A + + A V I EV ++ + A G AV Sbjct: 5 LKGKVVAITGAASGLGKAMAIRFGKEQAKVVINYYSNKQDPNEVKEEVIKA----GGEAV 60 Query: 352 GFQGDVRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVGT 531 QGDV +ED ++ + ++ FG LDI++N A ++ K + V+ + G Sbjct: 61 VVQGDVTKEEDVKNIVQTAIKEFGTLDIMINNAGLENPVPSHEMPLKDWDKVIGTNLTGA 120 Query: 532 YTMCYEAL 555 + EA+ Sbjct: 121 FLGSREAI 128
>IDNO_ECOLI (P0A9P9) Gluconate 5-dehydrogenase (EC 1.1.1.69)| (5-keto-D-gluconate 5-reductase) Length = 254 Score = 51.2 bits (121), Expect = 2e-06 Identities = 30/88 (34%), Positives = 45/88 (51%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGD 366 L GK LITG GI F +A L ++GA + I E + AV L EG++AV + Sbjct: 7 LAGKNILITGSAQGIGFLLATGLGKYGAQIIINDITAERAELAVEKLHQEGIQAVAAPFN 66 Query: 367 VRNQEDAARVLASTVEHFGKLDILVNGA 450 V ++ + + + G +D+LVN A Sbjct: 67 VTHKHEIDAAVEHIEKDIGPIDVLVNNA 94
>IDNO_ECOL6 (P0A9Q0) Gluconate 5-dehydrogenase (EC 1.1.1.69)| (5-keto-D-gluconate 5-reductase) Length = 254 Score = 51.2 bits (121), Expect = 2e-06 Identities = 30/88 (34%), Positives = 45/88 (51%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGD 366 L GK LITG GI F +A L ++GA + I E + AV L EG++AV + Sbjct: 7 LAGKNILITGSAQGIGFLLATGLGKYGAQIIINDITAERAELAVEKLHQEGIQAVAAPFN 66 Query: 367 VRNQEDAARVLASTVEHFGKLDILVNGA 450 V ++ + + + G +D+LVN A Sbjct: 67 VTHKHEIDAAVEHIEKDIGPIDVLVNNA 94
>SOU1_SCHPO (Q9Y6Z9) Sorbitol utilization protein sou1 (EC 1.1.-.-)| Length = 255 Score = 51.2 bits (121), Expect = 2e-06 Identities = 37/122 (30%), Positives = 58/122 (47%), Gaps = 6/122 (4%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIM-GRRREVLDKAVAALRSEGLRAVGFQG 363 L+GK LITGG GI F IA A G++V ++ GR ++ L+ A G++A + Sbjct: 7 LKGKTTLITGGSGGIGFSIAKAFAAAGSNVGLLYGRNKKALEYAAELRDKHGVQAKAYSC 66 Query: 364 DVRNQEDAARVLASTVEHF-GKLDILVNGAAGNFLASP----EDLTPKGFRTVLEIDTVG 528 + N+ VE G+LD+++ A +A P ED + V+ I+ G Sbjct: 67 PIENRSAVIETTNQAVEELGGRLDVMIANAG---IAIPHLSLEDKNEDIWTKVVGINLNG 123 Query: 529 TY 534 Y Sbjct: 124 AY 125
>Y2146_BRAJA (Q45219) Probable short-chain type dehydrogenase/reductase blr2146| (EC 1.-.-.-) Length = 281 Score = 51.2 bits (121), Expect = 2e-06 Identities = 33/109 (30%), Positives = 52/109 (47%) Frame = +1 Query: 193 GKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGDVR 372 GK A++TG G+GI A +AR G V + A + +E A+ D+ Sbjct: 6 GKVAVVTGAGAGIGKACALAIAREGGRVVVADIDGSAAIACTAQIAAEAGHALALAIDIA 65 Query: 373 NQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEID 519 + + A + + HFG +D+LVN AS LTP+ R +LE++ Sbjct: 66 DAQAVAALFETAERHFGGVDLLVNN------ASAMHLTPRD-RAILELE 107
>DHI1_MOUSE (P50172) Corticosteroid 11-beta-dehydrogenase isozyme 1 (EC| 1.1.1.146) (11-DH) (11-beta-hydroxysteroid dehydrogenase 1) (11-beta-HSD1) (11beta-HSD1A) Length = 291 Score = 50.8 bits (120), Expect = 3e-06 Identities = 29/96 (30%), Positives = 49/96 (51%), Gaps = 1/96 (1%) Frame = +1 Query: 157 ATESPFRADVLRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSE 336 +T FR ++L+GK ++TG GI E+A L++ GAHV + R E L K V+ Sbjct: 21 STNEEFRPEMLQGKKVIVTGASKGIGREMAYHLSKMGAHVVLTARSEEGLQKVVSRCLEL 80 Query: 337 GLRAVGF-QGDVRNQEDAARVLASTVEHFGKLDILV 441 G + + G + + A + + + G LD+L+ Sbjct: 81 GAASAHYIAGTMEDMTFAEQFIVKAGKLMGGLDMLI 116
>RHLG_PSEAE (Q9RPT1) Rhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein]| reductase (EC 1.1.1.100) (3-ketoacyl-acyl carrier protein reductase) Length = 256 Score = 50.8 bits (120), Expect = 3e-06 Identities = 36/123 (29%), Positives = 56/123 (45%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGD 366 L G+ AL+TGG GI IA L GA V I R E L + G D Sbjct: 7 LAGRIALVTGGSRGIGQMIAQGLLEAGARVFICARDAEACADTATRLSAYG-DCQAIPAD 65 Query: 367 VRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVGTYTMCY 546 + ++ A R+ + E +LDILVN A ++ A+ E G+ V++++ ++ Sbjct: 66 LSSEAGARRLAQALGELSARLDILVNNAGTSWGAALESYPVSGWEKVMQLNVTSVFSCIQ 125 Query: 547 EAL 555 + L Sbjct: 126 QLL 128
>DHRS3_MOUSE (O88876) Short-chain dehydrogenase/reductase 3 (EC 1.1.-.-)| (Retinal short-chain dehydrogenase/reductase 1) (retSDR1) Length = 302 Score = 50.4 bits (119), Expect = 3e-06 Identities = 31/90 (34%), Positives = 46/90 (51%), Gaps = 1/90 (1%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAH-VAIMGRRREVLDKAVAALRSEGLRAVGFQG 363 L ++ LITGGG GI +A + A GA + + GR + L + +R G F Sbjct: 36 LSRESVLITGGGRGIGRHLAREFAERGARKIVLWGRTEKCLKETTEEIRQMGTECHYFIC 95 Query: 364 DVRNQEDAARVLASTVEHFGKLDILVNGAA 453 DV N+E+ ++ + E G + ILVN AA Sbjct: 96 DVGNREEVYQMAKAVREKVGDITILVNNAA 125
>LIGD_PSEPA (Q01198) C alpha-dehydrogenase (EC 1.-.-.-)| Length = 305 Score = 50.4 bits (119), Expect = 3e-06 Identities = 35/112 (31%), Positives = 52/112 (46%), Gaps = 1/112 (0%) Frame = +1 Query: 196 KAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGDVRN 375 + A ITGG SG F A + GA + + R E ++KAVA L G+ A G D+ + Sbjct: 7 QVAFITGGASGAGFGQAKVFGQAGAKIVVADVRAEAVEKAVAELEGLGITAHGIVLDIMD 66 Query: 376 QEDAARVLASTVEHFGKLDILVNGAAG-NFLASPEDLTPKGFRTVLEIDTVG 528 +E AR FG+ L++ AG N E T F ++ ++ G Sbjct: 67 REAYARAADEVEAVFGQAPTLLSNTAGVNSFGPIEKTTYDDFDWIIGVNLNG 118
>DHMA_FLAS1 (P22441) N-acylmannosamine 1-dehydrogenase (EC 1.1.1.233) (NAM-DH)| Length = 270 Score = 50.1 bits (118), Expect = 4e-06 Identities = 40/124 (32%), Positives = 55/124 (44%), Gaps = 5/124 (4%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGD 366 L GKAA++TG GI R GA V M L +AA R E A+ D Sbjct: 12 LAGKAAIVTGAAGGIGRATVEAYLREGASVVAMD-----LAPRLAATRYEEPGAIPIACD 66 Query: 367 VRNQEDAARVLASTVEHFGKLDILVNGAA-----GNFLASPEDLTPKGFRTVLEIDTVGT 531 + ++ +A V G LDILV G A GNFL DL+ + ++++ GT Sbjct: 67 LADRAAIDAAMADAVARLGGLDILVAGGALKGGTGNFL----DLSDADWDRYVDVNMTGT 122 Query: 532 YTMC 543 + C Sbjct: 123 FLTC 126
>FABG_PSEAE (O54438) 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100)| (3-ketoacyl-acyl carrier protein reductase) Length = 247 Score = 50.1 bits (118), Expect = 4e-06 Identities = 31/88 (35%), Positives = 42/88 (47%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGD 366 L+GK AL+TG GI IA +L R GA V +K L++ G+ G D Sbjct: 3 LQGKVALVTGASRGIGQAIALELGRLGAVVIGTATSASGAEKIAETLKANGVEGAGLVLD 62 Query: 367 VRNQEDAARVLASTVEHFGKLDILVNGA 450 V + E A L +H G+ I+VN A Sbjct: 63 VSSDESVAATLEHIQQHLGQPLIVVNNA 90
>LINX_PSEPA (P50198) 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase (EC| 1.1.1.-) (2,5-DDOL dehydrogenase) Length = 250 Score = 50.1 bits (118), Expect = 4e-06 Identities = 34/91 (37%), Positives = 46/91 (50%) Frame = +1 Query: 178 ADVLRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGF 357 A+ L GK ALITGG SG+ A + A GA V I E+ VA +R+ G A+ Sbjct: 2 ANRLAGKVALITGGASGLGAAQAKRFAEEGAKVVIGDLNEEMAKGVVAEIRAAGGDALFI 61 Query: 358 QGDVRNQEDAARVLASTVEHFGKLDILVNGA 450 + DV + +A+ V+ FG L L N A Sbjct: 62 RLDVTDAASWNNAIAAAVDGFGGLTTLSNTA 92
>DHRS3_HUMAN (O75911) Short-chain dehydrogenase/reductase 3 (EC 1.1.-.-)| (Retinal short-chain dehydrogenase/reductase 1) (retSDR1) (DD83.1) Length = 302 Score = 50.1 bits (118), Expect = 4e-06 Identities = 32/96 (33%), Positives = 47/96 (48%), Gaps = 1/96 (1%) Frame = +1 Query: 169 PFRADVLRGKAALITGGGSGICFEIAAQLARHGAH-VAIMGRRREVLDKAVAALRSEGLR 345 P + L + LITGGG GI ++A + A GA + + GR + L + +R G Sbjct: 30 PAKLRDLSRENVLITGGGRGIGRQLAREFAERGARKIVLWGRTEKCLKETTEEIRQMGTE 89 Query: 346 AVGFQGDVRNQEDAARVLASTVEHFGKLDILVNGAA 453 F DV N+E+ + + E G + ILVN AA Sbjct: 90 CHYFICDVGNREEVYQTAKAVREKVGDITILVNNAA 125
>RIDH_KLEAE (P00335) Ribitol 2-dehydrogenase (EC 1.1.1.56) (RDH)| Length = 249 Score = 50.1 bits (118), Expect = 4e-06 Identities = 35/96 (36%), Positives = 47/96 (48%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGD 366 L GK A ITG SGI E A L GA V ++ R E L+K VA L G A Q D Sbjct: 12 LSGKVAAITGAASGIGLECARTLLGAGAKVVLIDREGEKLNKLVAEL---GENAFALQVD 68 Query: 367 VRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASP 474 + + +L ++ G+LDI + AG ++ P Sbjct: 69 LMQADQVDNLLQGILQLTGRLDIF-HANAGAYIGGP 103
>HCDR_XANP2 (Q56840) 2-(R)-hydroxypropyl-CoM dehydrogenase (EC 1.1.1.268)| (R-HPCDH) (Aliphatic epoxide carboxylation component III) Length = 249 Score = 50.1 bits (118), Expect = 4e-06 Identities = 35/124 (28%), Positives = 58/124 (46%), Gaps = 4/124 (3%) Frame = +1 Query: 196 KAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAA-LRSEGLRAVGFQGDVR 372 + A++TG SG IA + G VA + E L++ + + + + DV Sbjct: 2 RVAIVTGASSGNGLAIATRFLARGDRVAALDLSAETLEETARTHWHAYADKVLRVRADVA 61 Query: 373 NQEDAARVLASTVEHFGKLDILVN--GAAGNFLASPEDLTP-KGFRTVLEIDTVGTYTMC 543 ++ D +A+T+E FG +D+LVN G GN A TP + F V+ ++ G + C Sbjct: 62 DEGDVNAAIAATMEQFGAIDVLVNNAGITGNSEAGVLHTTPVEQFDKVMAVNVRGIFLGC 121 Query: 544 YEAL 555 L Sbjct: 122 RAVL 125
>HETN_ANASP (P37694) Ketoacyl reductase hetN (EC 1.3.1.-)| Length = 287 Score = 49.7 bits (117), Expect = 6e-06 Identities = 27/88 (30%), Positives = 45/88 (51%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGD 366 L GK L+TG G+ IA LA+ A V + R + L + A+++ G +A+ D Sbjct: 4 LTGKTVLLTGASRGLGVYIARALAKEQATVVCVSRSQSGLAQTCNAVKAAGGKAIAIPFD 63 Query: 367 VRNQEDAARVLASTVEHFGKLDILVNGA 450 VRN + ++ + G +D+L+N A Sbjct: 64 VRNTSQLSALVQQAQDIVGPIDVLINNA 91
>BPHB_PSEPU (P72220) Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase (EC| 1.3.1.56) (Biphenyl-2,3-dihydro-2,3-diol dehydrogenase) (2,3-dihydro-2,3-dihydroxybiphenyl dehydrogenase) (Biphenyl-cis-diol dehydrogenase) (2,3-dihydroxy-4-phenylhexa-4,6-diene dehyd Length = 277 Score = 49.3 bits (116), Expect = 7e-06 Identities = 37/120 (30%), Positives = 56/120 (46%), Gaps = 6/120 (5%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSE-GLRAVGFQG 363 L G+ LITGG SG+ + + A VA++ + E L A L ++ G +G G Sbjct: 3 LTGEVVLITGGASGLGRALVDRFVAERAKVAVLDKSAERL----AQLETDHGDNVLGVTG 58 Query: 364 DVRNQEDAARVLASTVEHFGKLDILVNGA-----AGNFLASPEDLTPKGFRTVLEIDTVG 528 DVR+ ED + + V FGK+D L+ A + + PE+ F V I+ G Sbjct: 59 DVRSLEDQKQAASRCVAKFGKIDTLIPNAGIWDYSTALIDLPEESLDAAFDEVFHINVKG 118
>FABG_CHLMU (Q9PKF7) 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100)| (3-ketoacyl-acyl carrier protein reductase) Length = 248 Score = 49.3 bits (116), Expect = 7e-06 Identities = 34/121 (28%), Positives = 57/121 (47%), Gaps = 1/121 (0%) Frame = +1 Query: 184 VLRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQ- 360 +L KAA++TGG GI F IA A HGA+V I G E A L + V F Sbjct: 4 LLVNKAAIVTGGSRGIGFGIAKLFAEHGANVQIWGINEEAGKSAAQDLSDKTGSKVSFAL 63 Query: 361 GDVRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVGTYTM 540 DV + + + + +G +D++VN A + ++ + + +V++ + Y + Sbjct: 64 VDVSKNDMVSAQVQKFLAEYGTIDVVVNNAGITRDSLLMRMSEEEWSSVIDTNLGSIYNV 123 Query: 541 C 543 C Sbjct: 124 C 124
>BPHB_RHOGO (P47230) Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase (EC| 1.3.1.56) (Biphenyl-2,3-dihydro-2,3-diol dehydrogenase) (2,3-dihydro-2,3-dihydroxybiphenyl dehydrogenase) (Biphenyl-cis-diol dehydrogenase) (2,3-dihydroxy-4-phenylhexa-4,6-diene dehyd Length = 280 Score = 48.9 bits (115), Expect = 1e-05 Identities = 36/119 (30%), Positives = 55/119 (46%), Gaps = 5/119 (4%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGD 366 L+ + L+TGG +G+ I + GA VA++ R L++ AA G V +GD Sbjct: 3 LQDEVVLVTGGCAGLGRAIVDRFVCEGARVAVLDRSVAGLEELRAA---HGDAVVAVEGD 59 Query: 367 VRNQEDAARVLASTVEHFGKLDILVNGA-----AGNFLASPEDLTPKGFRTVLEIDTVG 528 VR + +A VE FGKLD + A + + PED + F + I+ G Sbjct: 60 VRYLDSHKETVAKCVETFGKLDCYIGNAGVWDYSTALVEIPEDRLDEAFDEMYSINVKG 118
>FOX2_CANTR (P22414) Peroxisomal hydratase-dehydrogenase-epimerase (HDE)| (Multifunctional beta-oxidation protein) (MFP) [Includes: 2-enoyl-CoA hydratase (EC 4.2.1.-); D-3-hydroxyacyl CoA dehydrogenase (EC 1.1.1.-)] Length = 906 Score = 48.9 bits (115), Expect = 1e-05 Identities = 33/118 (27%), Positives = 62/118 (52%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGD 366 L+ K LITG G+G+ E A A++GA V + + K V +++ G A Q D Sbjct: 320 LKDKVVLITGAGAGLGKEYAKWFAKYGAKVVVNDFKDAT--KTVDEIKAAGGEAWPDQHD 377 Query: 367 VRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVGTYTM 540 V +D+ ++ + ++ +G +DILVN A S ++ + + +V ++ +GT+ + Sbjct: 378 V--AKDSEAIIKNVIDKYGTIDILVNNAGILRDRSFAKMSKQEWDSVQQVHLIGTFNL 433 Score = 43.9 bits (102), Expect = 3e-04 Identities = 30/126 (23%), Positives = 58/126 (46%), Gaps = 9/126 (7%) Frame = +1 Query: 190 RGKAALITGGGSGICFEIAAQLARHGAHVAI---------MGRRREVLDKAVAALRSEGL 342 + K +ITG G G+ + + A+ GA V + G + D V + G Sbjct: 7 KDKVVIITGAGGGLGKYYSLEFAKLGAKVVVNDLGGALNGQGGNSKAADVVVDEIVKNGG 66 Query: 343 RAVGFQGDVRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDT 522 AV D N D +++ + V++FG + +++N A AS + +T K ++ V+++ Sbjct: 67 VAV---ADYNNVLDGDKIVETAVKNFGTVHVIINNAGILRDASMKKMTEKDYKLVIDVHL 123 Query: 523 VGTYTM 540 G + + Sbjct: 124 NGAFAV 129
>Y1570_MYCBO (P66780) Putative oxidoreductase Mb1570 (EC 1.-.-.-)| Length = 341 Score = 48.9 bits (115), Expect = 1e-05 Identities = 32/102 (31%), Positives = 50/102 (49%), Gaps = 3/102 (2%) Frame = +1 Query: 181 DVLRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKA---VAALRSEGLRAV 351 D ++GK LITGG SGI A ++A G V ++ R E L+ + A+R G A Sbjct: 49 DAVKGKVVLITGGSSGIGAAAAKKIAEAGGTVVLVARTLENLENVANDIRAIRGNGGTAH 108 Query: 352 GFQGDVRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPE 477 + D+ + + A + + G +DIL+N A + S E Sbjct: 109 VYPCDLSDMDAIAVMADQVLGDLGGVDILINNAGRSIRRSLE 150
>Y1543_MYCTU (P66779) Putative oxidoreductase Rv1543/MT1595 (EC 1.-.-.-)| Length = 341 Score = 48.9 bits (115), Expect = 1e-05 Identities = 32/102 (31%), Positives = 50/102 (49%), Gaps = 3/102 (2%) Frame = +1 Query: 181 DVLRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKA---VAALRSEGLRAV 351 D ++GK LITGG SGI A ++A G V ++ R E L+ + A+R G A Sbjct: 49 DAVKGKVVLITGGSSGIGAAAAKKIAEAGGTVVLVARTLENLENVANDIRAIRGNGGTAH 108 Query: 352 GFQGDVRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPE 477 + D+ + + A + + G +DIL+N A + S E Sbjct: 109 VYPCDLSDMDAIAVMADQVLGDLGGVDILINNAGRSIRRSLE 150
>BPHB_PSEPS (P08694) Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase (EC| 1.3.1.56) (Biphenyl-2,3-dihydro-2,3-diol dehydrogenase) (2,3-dihydro-2,3-dihydroxybiphenyl dehydrogenase) (Biphenyl-cis-diol dehydrogenase) (2,3-dihydroxy-4-phenylhexa-4,6-diene dehyd Length = 275 Score = 48.5 bits (114), Expect = 1e-05 Identities = 37/119 (31%), Positives = 56/119 (47%), Gaps = 5/119 (4%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGD 366 L+G+A LITGG SG+ + + A VA++ + E L + L G +G GD Sbjct: 3 LKGEAVLITGGASGLGRALVDRFVAE-AKVAVLDKSAERLAELETDL---GDNVLGIVGD 58 Query: 367 VRNQEDAARVLASTVEHFGKLDILVNGA-----AGNFLASPEDLTPKGFRTVLEIDTVG 528 VR+ ED + + V FGK+D L+ A + + PE+ F V I+ G Sbjct: 59 VRSLEDQKQAASRCVARFGKIDTLIPNAGIWDYSTALVDLPEESLDAAFDEVFHINVKG 117
>BDHA_RHIME (O86034) D-beta-hydroxybutyrate dehydrogenase (EC 1.1.1.30) (BDH)| (3-hydroxybutyrate dehydrogenase) (3-HBDH) Length = 258 Score = 48.1 bits (113), Expect = 2e-05 Identities = 36/118 (30%), Positives = 58/118 (49%), Gaps = 5/118 (4%) Frame = +1 Query: 196 KAALITGGGSGICFEIAAQLARHGAHVAIMG-----RRREVLDKAVAALRSEGLRAVGFQ 360 K A+ITG SGI IA LA+ GA++ + G R V D+ VA L S + + Sbjct: 3 KTAVITGSTSGIGLAIARTLAKAGANIVLNGFGAPDEIRTVTDE-VAGLSSGTV--LHHP 59 Query: 361 GDVRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVGTY 534 D+ + A ++A + FG DILVN A F+ ED + + ++ ++ ++ Sbjct: 60 ADMTKPSEIADMMAMVADRFGGADILVNNAGVQFVEKIEDFPVEQWDRIIAVNLSSSF 117
>YOHF_ECOLI (P33368) Hypothetical oxidoreductase yohF (EC 1.-.-.-)| Length = 253 Score = 48.1 bits (113), Expect = 2e-05 Identities = 35/114 (30%), Positives = 53/114 (46%), Gaps = 1/114 (0%) Frame = +1 Query: 196 KAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAA-LRSEGLRAVGFQGDVR 372 + A+IT SGI E A LA+ G + I E K A + S G+RA Q D+ Sbjct: 3 QVAIITASDSGIGKECALLLAQQGFDIGITWHSDEEGAKDTAREVVSHGVRAEIVQLDLG 62 Query: 373 NQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVGTY 534 N + A L ++ G++D+LVN A A D+ +R + +D G + Sbjct: 63 NLPEGALALEKLIQRLGRIDVLVNNAGAMTKAPFLDMAFDEWRKIFTVDVDGAF 116
>BACC2_BACSU (Q8KWT4) Bacilysin biosynthesis oxidoreductase bacC (EC 1.-.-.-)| Length = 253 Score = 48.1 bits (113), Expect = 2e-05 Identities = 35/126 (27%), Positives = 56/126 (44%), Gaps = 3/126 (2%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAV--AALRSEGLRAVGF- 357 L K LITGG SGI + A+V + +D+A A +R E + F Sbjct: 3 LTDKTVLITGGASGIGYAAVQAFLNQQANVVVAD-----IDEAQGEAMIRKENNDRLHFV 57 Query: 358 QGDVRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVGTYT 537 D+ ++ + S V+ FG LD+L+N A +A ++ + VL ++ G + Sbjct: 58 HTDITDEPACQNAIRSAVDKFGGLDVLINNAGIEIVAPIHEMELSNWNKVLNVNLTGMFL 117 Query: 538 MCYEAL 555 M AL Sbjct: 118 MSKHAL 123
>DHR11_CHICK (Q71R50) Dehydrogenase/reductase SDR family member 11 precursor (EC| 1.-.-.-) Length = 255 Score = 48.1 bits (113), Expect = 2e-05 Identities = 33/125 (26%), Positives = 61/125 (48%), Gaps = 5/125 (4%) Frame = +1 Query: 193 GKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGL--RAVGFQGD 366 G+ AL+TG GI +A L +HG V R + ++K A +S G + ++ D Sbjct: 6 GRVALVTGASVGIGAAVARALVQHGMKVVGCARSVDKIEKLAAECQSAGYPGTLIPYKCD 65 Query: 367 VRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDL---TPKGFRTVLEIDTVGTYT 537 + N+E+ + ++ +D+ +N A LA PE L +G+RT+++++ + Sbjct: 66 LSNEEEILSMFSAIKTLHQGVDVCINNAG---LARPEPLLSGKTEGWRTMIDVNVMAVSI 122 Query: 538 MCYEA 552 EA Sbjct: 123 CTREA 127
>DHI1_MESAU (Q6R0J2) Corticosteroid 11-beta-dehydrogenase isozyme 1 (EC| 1.1.1.146) (11-DH) (11-beta-hydroxysteroid dehydrogenase 1) (11-beta-HSD1) (7-alpha-hydroxycholesterol dehydrogenase) (7-alpha-HCD) Length = 291 Score = 48.1 bits (113), Expect = 2e-05 Identities = 28/96 (29%), Positives = 48/96 (50%), Gaps = 1/96 (1%) Frame = +1 Query: 157 ATESPFRADVLRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSE 336 +T+ FR ++L+GK ++TG GI E+A L+ GAHV + R E L K + Sbjct: 21 STKEEFRPEMLQGKKVIVTGASKGIGREMAYHLSEMGAHVVLTARSEEGLQKVASRCLEL 80 Query: 337 GLRAVGF-QGDVRNQEDAARVLASTVEHFGKLDILV 441 G + + G + + A + + + G LD+L+ Sbjct: 81 GAASAHYIAGTMEDMTFAEQFVLKAGKLMGGLDMLI 116
>DHCA_MOUSE (P48758) Carbonyl reductase [NADPH] 1 (EC 1.1.1.184)| (NADPH-dependent carbonyl reductase 1) Length = 276 Score = 47.8 bits (112), Expect = 2e-05 Identities = 36/119 (30%), Positives = 52/119 (43%), Gaps = 1/119 (0%) Frame = +1 Query: 202 ALITGGGSGICFEIAAQLARH-GAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGDVRNQ 378 AL+TG GI F I L R V + R E AV L++EGL Q D+ N Sbjct: 7 ALVTGANKGIGFAITRDLCRKFSGDVVLAARDEERGQTAVQKLQAEGLSPRFHQLDIDNP 66 Query: 379 EDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVGTYTMCYEAL 555 + + ++ +G LD+LVN A F + + +E + GT +C E L Sbjct: 67 QSIRALRDFLLKEYGGLDVLVNKAGIAFKVNDDTPFHIQAEVTMETNFFGTRDVCKELL 125
>YGHA_ECOLI (P0AG84) Hypothetical oxidoreductase yghA (EC 1.-.-.-)| Length = 294 Score = 47.8 bits (112), Expect = 2e-05 Identities = 39/127 (30%), Positives = 61/127 (48%), Gaps = 4/127 (3%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAI--MGRRREVLDKAVAALRSEGLRAVGFQ 360 L+ + AL+TGG SGI A AR GA VAI + E + G +AV Sbjct: 47 LKDRKALVTGGDSGIGRAAAIAYAREGADVAISYLPVEEEDAQDVKKIIEECGRKAVLLP 106 Query: 361 GDVRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPE--DLTPKGFRTVLEIDTVGTY 534 GD+ +++ A ++ + G LDI+ AG +A P+ DLT + F+ I+ + Sbjct: 107 GDLSDEKFARSLVHEAHKALGGLDIMAL-VAGKQVAIPDIADLTSEQFQKTFAINVFALF 165 Query: 535 TMCYEAL 555 + EA+ Sbjct: 166 WLTQEAI 172
>YGHA_ECO57 (P0AG85) Hypothetical oxidoreductase yghA (EC 1.-.-.-)| Length = 294 Score = 47.8 bits (112), Expect = 2e-05 Identities = 39/127 (30%), Positives = 61/127 (48%), Gaps = 4/127 (3%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAI--MGRRREVLDKAVAALRSEGLRAVGFQ 360 L+ + AL+TGG SGI A AR GA VAI + E + G +AV Sbjct: 47 LKDRKALVTGGDSGIGRAAAIAYAREGADVAISYLPVEEEDAQDVKKIIEECGRKAVLLP 106 Query: 361 GDVRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPE--DLTPKGFRTVLEIDTVGTY 534 GD+ +++ A ++ + G LDI+ AG +A P+ DLT + F+ I+ + Sbjct: 107 GDLSDEKFARSLVHEAHKALGGLDIMAL-VAGKQVAIPDIADLTSEQFQKTFAINVFALF 165 Query: 535 TMCYEAL 555 + EA+ Sbjct: 166 WLTQEAI 172
>BACC_BACSU (P39640) Bacilysin biosynthesis oxidoreductase bacC (EC 1.-.-.-)| Length = 253 Score = 47.8 bits (112), Expect = 2e-05 Identities = 36/126 (28%), Positives = 57/126 (45%), Gaps = 3/126 (2%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAV--AALRSEGLRAVGF- 357 L K LITGG SGI + A+V + +D+A A +R E + F Sbjct: 3 LTDKTVLITGGASGIGYAAVQAFLGQQANVVVAD-----IDEAQGEAMVRKENNDRLHFV 57 Query: 358 QGDVRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVGTYT 537 Q D+ ++ + S V FG LD+L+N A +A ++ + VL+++ G + Sbjct: 58 QTDITDEAACQHAVESAVHTFGGLDVLINNAGIEIVAPIHEMELSDWNKVLQVNLTGMFL 117 Query: 538 MCYEAL 555 M AL Sbjct: 118 MSKHAL 123
>DHB4_HUMAN (P51659) Peroxisomal multifunctional enzyme type 2 (MFE-2)| (D-bifunctional protein) (DBP) (17-beta-hydroxysteroid dehydrogenase 4) (17-beta-HSD 4) [Includes: D-3-hydroxyacyl-CoA dehydratase (EC 4.2.1.107) (3-alpha,7-alpha,12-alpha-trihydroxy-5 Length = 735 Score = 47.4 bits (111), Expect = 3e-05 Identities = 32/104 (30%), Positives = 51/104 (49%), Gaps = 9/104 (8%) Frame = +1 Query: 166 SPFRADVLRGKAALITGGGSGICFEIAAQLARHGAHVAI---------MGRRREVLDKAV 318 SP R D G+ L+TG G+G+ A A GA V + +G+ DK V Sbjct: 2 SPLRFD---GRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVV 58 Query: 319 AALRSEGLRAVGFQGDVRNQEDAARVLASTVEHFGKLDILVNGA 450 +R G +AV V E+ +V+ + ++ FG++D++VN A Sbjct: 59 EEIRRRGGKAVANYDSV---EEGEKVVKTALDAFGRIDVVVNNA 99
>DHB4_MOUSE (P51660) Peroxisomal multifunctional enzyme type 2 (MFE-2)| (D-bifunctional protein) (DBP) (17-beta-hydroxysteroid dehydrogenase 4) (17-beta-HSD 4) [Includes: D-3-hydroxyacyl-CoA dehydratase (EC 4.2.1.107) (3-alpha,7-alpha,12-alpha-trihydroxy-5 Length = 734 Score = 47.4 bits (111), Expect = 3e-05 Identities = 32/104 (30%), Positives = 51/104 (49%), Gaps = 9/104 (8%) Frame = +1 Query: 166 SPFRADVLRGKAALITGGGSGICFEIAAQLARHGAHVAI---------MGRRREVLDKAV 318 SP R D G+ L+TG G G+ A A GA V + +G+ DK V Sbjct: 2 SPLRFD---GRVVLVTGAGGGLGRAYALAFAERGALVIVNDLGGDFKGIGKGSSAADKVV 58 Query: 319 AALRSEGLRAVGFQGDVRNQEDAARVLASTVEHFGKLDILVNGA 450 A +R +G +AV V E +++ + ++ FG++D++VN A Sbjct: 59 AEIRRKGGKAVANYDSV---EAGEKLVKTALDTFGRIDVVVNNA 99
>WWOX_MOUSE (Q91WL8) WW domain-containing oxidoreductase (EC 1.1.1.-)| Length = 414 Score = 47.4 bits (111), Expect = 3e-05 Identities = 42/122 (34%), Positives = 56/122 (45%), Gaps = 8/122 (6%) Frame = +1 Query: 193 GKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGDVR 372 GK L+TG SGI FE A A HGAHV + R +AV+ + E +A V Sbjct: 124 GKVVLVTGANSGIGFETAKSFALHGAHVILACRNLSRASEAVSRILEEWHKA-----KVE 178 Query: 373 NQEDAARVLASTVEHFGK--------LDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVG 528 VL S V+HF + L +LV AG F A P LT G T +++ +G Sbjct: 179 AMTLDLAVLRS-VQHFAEAFKAKNVSLHVLVCN-AGTF-ALPWGLTKDGLETTFQVNHLG 235 Query: 529 TY 534 + Sbjct: 236 HF 237
>HCD2_DROME (O18404) 3-hydroxyacyl-CoA dehydrogenase type-2 (EC 1.1.1.35)| (3-hydroxyacyl-CoA dehydrogenase type II) (Type II HADH) (3-hydroxy-2-methylbutyryl-CoA dehydrogenase) (EC 1.1.1.178) (Scully protein) Length = 255 Score = 47.0 bits (110), Expect = 4e-05 Identities = 33/125 (26%), Positives = 59/125 (47%), Gaps = 6/125 (4%) Frame = +1 Query: 184 VLRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQG 363 +++ +L+TGG SG+ A +LA+ GA V + K + G + V Sbjct: 1 MIKNAVSLVTGGASGLGRATAERLAKQGASVILADLPS---SKGNEVAKELGDKVVFVPV 57 Query: 364 DVRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTP------KGFRTVLEIDTV 525 DV +++D + L + + FG+LD+ VN A + + F+ V+ I+TV Sbjct: 58 DVTSEKDVSAALQTAKDKFGRLDLTVNCAGTATAVKTFNFNKNVAHRLEDFQRVININTV 117 Query: 526 GTYTM 540 GT+ + Sbjct: 118 GTFNV 122
>FOX2_NEUCR (Q01373) Peroxisomal hydratase-dehydrogenase-epimerase (HDE)| (Multifunctional beta-oxidation protein) (MFP) [Includes: 2-enoyl-CoA hydratase (EC 4.2.1.-); D-3-hydroxyacyl CoA dehydrogenase (EC 1.1.1.-)] Length = 894 Score = 47.0 bits (110), Expect = 4e-05 Identities = 30/87 (34%), Positives = 47/87 (54%) Frame = +1 Query: 190 RGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGDV 369 +G+ AL+TGGG+GI AR GA V + D V ++ G +AVG + Sbjct: 313 KGRVALVTGGGAGIGRAYCLAFARAGASVVVNDLVNP--DDVVNEIKKMGGKAVGAK--- 367 Query: 370 RNQEDAARVLASTVEHFGKLDILVNGA 450 + ED V+ + ++ FG++DI+VN A Sbjct: 368 FSAEDGDAVVKAAIDAFGRVDIVVNNA 394 Score = 39.3 bits (90), Expect = 0.008 Identities = 26/123 (21%), Positives = 55/123 (44%), Gaps = 9/123 (7%) Frame = +1 Query: 193 GKAALITGGGSGICFEIAAQLARHGAHVAIM---------GRRREVLDKAVAALRSEGLR 345 G+ ++TG G G+ GA V + G + D V +++ G + Sbjct: 9 GQVVVVTGAGGGLGKAYCLFFGSRGASVVVNDLGASFKGEGNSTKAADVVVNEIKAAGGK 68 Query: 346 AVGFQGDVRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTV 525 AV V N + +++ + ++ FG++DIL+N A S +++ + + + ++ Sbjct: 69 AVANYDSVENGD---KIIETAIKEFGRIDILINNAGILRDISFKNMKDEDWDLIFKVHVK 125 Query: 526 GTY 534 G+Y Sbjct: 126 GSY 128
>CPNA_COMTE (Q937L4) Cyclopentanol dehydrogenase (EC 1.1.1.163)| Length = 250 Score = 47.0 bits (110), Expect = 4e-05 Identities = 32/108 (29%), Positives = 51/108 (47%) Frame = +1 Query: 196 KAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGDVRN 375 K L+TGG G+ LAR GA V + E+ +AVA +R +G +A DV N Sbjct: 7 KVVLVTGGAMGMGLTHCTLLAREGATVYLSDMNEELGHQAVAEIRRQGGKAHFLHLDVTN 66 Query: 376 QEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEID 519 + + + + +LD LVN A L +D + + + + EI+ Sbjct: 67 ENHWTGAVDTILAESDRLDALVNNAGILTLKPVQDTSNEEWDRIFEIN 114
>CPNA_COMS9 (Q8GAV9) Cyclopentanol dehydrogenase (EC 1.1.1.163)| Length = 250 Score = 47.0 bits (110), Expect = 4e-05 Identities = 32/108 (29%), Positives = 51/108 (47%) Frame = +1 Query: 196 KAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGDVRN 375 K L+TGG G+ LAR GA V + E+ +AVA +R +G +A DV N Sbjct: 7 KVVLVTGGAMGMGLTHCTLLAREGATVYLSDMNEELGHQAVAEIRRQGGKAHFLHLDVTN 66 Query: 376 QEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEID 519 + + + + +LD LVN A L +D + + + + EI+ Sbjct: 67 ENHWTGAVDTILAESDRLDALVNNAGILTLKPVQDTSNEEWDRIFEIN 114
>LVR_LEIAQ (Q9LBG2) Levodione reductase (EC 1.1.1.-)| ((6R)-2,2,6-trimethyl-1,4-cyclohexanedione reductase) Length = 267 Score = 46.6 bits (109), Expect = 5e-05 Identities = 37/129 (28%), Positives = 59/129 (45%), Gaps = 3/129 (2%) Frame = +1 Query: 157 ATESPFRADVLRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAAL--R 330 AT SP + LITGGGSG+ A +LA GA ++++ E L+ + AA+ Sbjct: 3 ATSSPTTR--FTDRVVLITGGGSGLGRATAVRLAAEGAKLSLVDVSSEGLEASKAAVLET 60 Query: 331 SEGLRAVGFQGDVRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASP-EDLTPKGFRTV 507 + + DV ++ + +T E FG++D N A +P E T F V Sbjct: 61 APDAEVLTTVADVSDEAQVEAYVTATTERFGRIDGFFNNAGIEGKQNPTESFTAAEFDKV 120 Query: 508 LEIDTVGTY 534 + I+ G + Sbjct: 121 VSINLRGVF 129
>HCD2_HUMAN (Q99714) 3-hydroxyacyl-CoA dehydrogenase type-2 (EC 1.1.1.35)| (3-hydroxyacyl-CoA dehydrogenase type II) (Type II HADH) (3-hydroxy-2-methylbutyryl-CoA dehydrogenase) (EC 1.1.1.178) (Endoplasmic reticulum-associated amyloid beta-peptide binding Length = 260 Score = 46.6 bits (109), Expect = 5e-05 Identities = 36/125 (28%), Positives = 58/125 (46%), Gaps = 7/125 (5%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGD 366 ++G A+ITGG SG+ A +L GA ++ A + G V D Sbjct: 7 VKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPN---SGGEAQAKKLGNNCVFAPAD 63 Query: 367 VRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKG-------FRTVLEIDTV 525 V +++D LA FG++D+ VN AG +AS KG F+ VL+++ + Sbjct: 64 VTSEKDVQTALALAKGKFGRVDVAVN-CAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLM 122 Query: 526 GTYTM 540 GT+ + Sbjct: 123 GTFNV 127
>WWOX_PONPY (Q5R9W5) WW domain-containing oxidoreductase (EC 1.1.1.-)| Length = 414 Score = 46.6 bits (109), Expect = 5e-05 Identities = 38/125 (30%), Positives = 57/125 (45%), Gaps = 11/125 (8%) Frame = +1 Query: 193 GKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGDVR 372 GK ++TG SGI FE A A HGAHV + R +AV+ + E +A Sbjct: 124 GKVVVVTGANSGIGFETAKSFALHGAHVILACRNMARASEAVSRILEEWHKA-------- 175 Query: 373 NQEDAARV---LASTVEHFGK--------LDILVNGAAGNFLASPEDLTPKGFRTVLEID 519 + +A + L +V+HF + L +LV AA A P LT G T +++ Sbjct: 176 -KVEAVTLDLALLRSVQHFAEAFKAKNVPLHVLVCNAA--TFALPWSLTKDGLETTFQVN 232 Query: 520 TVGTY 534 +G + Sbjct: 233 HLGHF 237
>WWOX_HUMAN (Q9NZC7) WW domain-containing oxidoreductase (EC 1.1.1.-) (Fragile| site FRA16D oxidoreductase) Length = 414 Score = 46.6 bits (109), Expect = 5e-05 Identities = 38/122 (31%), Positives = 57/122 (46%), Gaps = 8/122 (6%) Frame = +1 Query: 193 GKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGDVR 372 GK ++TG SGI FE A A HGAHV + R +AV+ + E +A + + Sbjct: 124 GKVVVVTGANSGIGFETAKSFALHGAHVILACRNMARASEAVSRILEEWHKA---KVEAM 180 Query: 373 NQEDAARVLASTVEHFGK--------LDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVG 528 + A L +V+HF + L +LV AA A P LT G T +++ +G Sbjct: 181 TLDLA---LLRSVQHFAEAFKAKNVPLHVLVCNAA--TFALPWSLTKDGLETTFQVNHLG 235 Query: 529 TY 534 + Sbjct: 236 HF 237
>YHXD_BACSU (P40398) Hypothetical oxidoreductase yhxD (EC 1.-.-.-) (ORFY)| Length = 299 Score = 46.2 bits (108), Expect = 6e-05 Identities = 36/126 (28%), Positives = 58/126 (46%), Gaps = 3/126 (2%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAI--MGRRREVLDKAVAALRSEGLRAVGFQ 360 L G+ AL+TGG SGI A AR GA VAI + + ++ + +EG +AV Sbjct: 49 LTGRKALVTGGDSGIGRAAAIAYAREGADVAINYLPEEQPDAEEVKELIEAEGRKAVLIP 108 Query: 361 GDVRNQEDAARVLASTVEHFGKLDILVNGAA-GNFLASPEDLTPKGFRTVLEIDTVGTYT 537 GD+ ++ ++ + G LD+L A + + EDL + E++ Y Sbjct: 109 GDLSDESFCQDLVKQSHHELGGLDVLALVAGKQQAVENIEDLPTEQIYKTFEVNVFSLYW 168 Query: 538 MCYEAL 555 + AL Sbjct: 169 VVKAAL 174
>BUDC_KLEPN (Q48436) Acetoin(diacetyl) reductase (EC 1.1.1.5) (Acetoin| dehydrogenase) (AR) (Meso-2,3-butanediol dehydrogenase) Length = 256 Score = 45.8 bits (107), Expect = 8e-05 Identities = 31/111 (27%), Positives = 48/111 (43%) Frame = +1 Query: 196 KAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGDVRN 375 K AL+TG G GI IA +L + G VAI + + G RA+ + DV + Sbjct: 3 KVALVTGAGQGIGKAIALRLVKDGFAVAIADYNDATAKAVASEINQAGGRAMAVKVDVSD 62 Query: 376 QEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVG 528 ++ + + G D++VN A E +TP+ V I+ G Sbjct: 63 RDQVFAAVEQARKTLGGFDVIVNNAGVAPSTPIESITPEIVDKVYNINVKG 113
>SDR1_PICAB (Q08632) Short-chain type dehydrogenase/reductase (EC 1.-.-.-)| Length = 271 Score = 45.8 bits (107), Expect = 8e-05 Identities = 30/95 (31%), Positives = 46/95 (48%), Gaps = 7/95 (7%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAAL-------RSEGLR 345 L G+ A++TG GI EIA +A GA V I + + VA++ +G+R Sbjct: 19 LGGRVAIVTGASRGIGREIALNMAEKGAKVVIHYSSNQHAAEEVASIINNKSPSSGDGVR 78 Query: 346 AVGFQGDVRNQEDAARVLASTVEHFGKLDILVNGA 450 A+ + DV A++ + FG L I+VN A Sbjct: 79 AIVCKADVAEPSQVAQLFDTAEHAFGPLHIVVNNA 113
>FABG_CUPLA (P28643) 3-oxoacyl-[acyl-carrier-protein] reductase, chloroplast| precursor (EC 1.1.1.100) (3-ketoacyl-acyl carrier protein reductase) Length = 320 Score = 45.4 bits (106), Expect = 1e-04 Identities = 30/117 (25%), Positives = 58/117 (49%), Gaps = 1/117 (0%) Frame = +1 Query: 205 LITGGGSGICFEIAAQLARHGAHVAI-MGRRREVLDKAVAALRSEGLRAVGFQGDVRNQE 381 ++TG GI IA L + G V + R + ++ + + G +A+ F GDV +E Sbjct: 81 IVTGASRGIGKAIALSLGKAGCKVLVNYARSSKEAEEVSKEIEAFGGQALTFGGDVSKEE 140 Query: 382 DAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVGTYTMCYEA 552 D ++ + V+ +G +DILVN A + ++ V++++ G + +C +A Sbjct: 141 DVEAMIKTAVDAWGTVDILVNNAGITRDGLLMRMKKSQWQEVIDLNLTGVF-LCTQA 196
>DHRS1_MOUSE (Q99L04) Dehydrogenase/reductase SDR family member 1 (EC 1.1.-.-)| Length = 313 Score = 45.4 bits (106), Expect = 1e-04 Identities = 33/90 (36%), Positives = 45/90 (50%), Gaps = 2/90 (2%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGD 366 ++G+ ++TG GI IA QL + GA V I GR + L +S G R V D Sbjct: 5 MKGQVCVVTGASRGIGRGIALQLCKAGATVYITGRHLDTLRATAQEAQSLGGRCVPVVCD 64 Query: 367 VRNQEDAARVLASTV--EHFGKLDILVNGA 450 +QE + L V E G+LD+LVN A Sbjct: 65 -SSQESEVKSLFEQVDREQKGRLDVLVNNA 93
>DHB4_RAT (P97852) Peroxisomal multifunctional enzyme type 2 (MFE-2)| (D-bifunctional protein) (DBP) (17-beta-hydroxysteroid dehydrogenase 4) (17-beta-HSD 4) [Includes: D-3-hydroxyacyl-CoA dehydratase (EC 4.2.1.107) (3-alpha,7-alpha,12-alpha-trihydroxy-5-b Length = 734 Score = 45.4 bits (106), Expect = 1e-04 Identities = 31/104 (29%), Positives = 49/104 (47%), Gaps = 9/104 (8%) Frame = +1 Query: 166 SPFRADVLRGKAALITGGGSGICFEIAAQLARHGAHVAI---------MGRRREVLDKAV 318 SP R D G+ L+TG G G+ A A GA V + +G+ DK V Sbjct: 2 SPLRFD---GRVVLVTGAGGGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSSAADKVV 58 Query: 319 AALRSEGLRAVGFQGDVRNQEDAARVLASTVEHFGKLDILVNGA 450 +R G +AV V E +++ + ++ FG++D++VN A Sbjct: 59 EEIRRRGGKAVANYDSV---EAGEKLVKTALDTFGRIDVVVNNA 99
>PHBB_CHRVI (P45375) Acetoacetyl-CoA reductase (EC 1.1.1.36)| Length = 246 Score = 44.7 bits (104), Expect = 2e-04 Identities = 30/87 (34%), Positives = 43/87 (49%), Gaps = 2/87 (2%) Frame = +1 Query: 196 KAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVL--DKAVAALRSEGLRAVGFQGDV 369 + AL+TGG GI I +LA+ G V E ++ A +EG F DV Sbjct: 3 RIALVTGGIGGIGTSICTRLAKDGCTVVANCHPSEAAAAEEWKQARAAEGFDIAVFTADV 62 Query: 370 RNQEDAARVLASTVEHFGKLDILVNGA 450 + +D+AR++ E G +DILVN A Sbjct: 63 SSFDDSARMVREITEQVGPIDILVNCA 89
>SDH_AGRTU (Q9KWN1) Serine 3-dehydrogenase (EC 1.1.1.276)| Length = 249 Score = 44.3 bits (103), Expect = 2e-04 Identities = 36/118 (30%), Positives = 54/118 (45%), Gaps = 1/118 (0%) Frame = +1 Query: 205 LITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGDVRNQED 384 LITG SG A + + G V GRR E L+ A L S V F D+ ++E Sbjct: 6 LITGATSGFGQATAQRFVKEGWKVIGTGRRAERLEALSAELGS-AFHGVAF--DITDEEA 62 Query: 385 AARVLASTVEHFGKLDILVNGAAGNFLASPEDLTP-KGFRTVLEIDTVGTYTMCYEAL 555 + LA + F +DILVN A +P P K ++T+++ + G + + L Sbjct: 63 TKKALAGLPDGFRDIDILVNNAGLALGTAPAPQVPLKDWQTMVDTNITGLLNVTHHLL 120
>HCAB_ECOLI (P77646) 2,3-dihydroxy-2,3-dihydro-phenylpropionate dehydrogenase| (EC 1.3.1.-) Length = 270 Score = 44.3 bits (103), Expect = 2e-04 Identities = 31/120 (25%), Positives = 53/120 (44%), Gaps = 6/120 (5%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSE-GLRAVGFQG 363 L ++ ITGGGSG+ + + GA VA + E+ VA+LR G + +G Sbjct: 4 LHNESIFITGGGSGLGLALVERFIEEGAQVATL----ELSAAKVASLRQRFGEHILAVEG 59 Query: 364 DVRNQEDAARVLASTVEHFGKLDILVNGAA-----GNFLASPEDLTPKGFRTVLEIDTVG 528 +V D R + + GKLD + A + + +P + GF + ++ +G Sbjct: 60 NVTCYADYQRAVDQILTRSGKLDCFIGNAGIWDHNASLVNTPAETLETGFHELFNVNVLG 119
>YQJQ_BACSU (P54554) Hypothetical oxidoreductase yqjQ (EC 1.-.-.-)| Length = 259 Score = 44.3 bits (103), Expect = 2e-04 Identities = 33/115 (28%), Positives = 50/115 (43%), Gaps = 1/115 (0%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSE-GLRAVGFQG 363 + GK ITG G+ IA A GAHV + RR + L + + E + F Sbjct: 4 IAGKRIWITGASGGLGERIAYLCAAEGAHVLLSARREDRLIEIKRKITEEWSGQCEIFPL 63 Query: 364 DVRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVG 528 DV ED ARV + G +D+L+N A + D T + + +++ G Sbjct: 64 DVGRLEDIARVR----DQIGSIDVLINNAGFGIFETVLDSTLDDMKAMFDVNVFG 114
>MTDH_CLAHE (P0C0Y5) Probable NADP-dependent mannitol dehydrogenase (EC| 1.1.1.138) (MtDH) (Mannitol 2-dehydrogenase [NADP+]) (Allergen Cla h 8) Length = 267 Score = 43.9 bits (102), Expect = 3e-04 Identities = 32/120 (26%), Positives = 60/120 (50%), Gaps = 4/120 (3%) Frame = +1 Query: 187 LRGKAALITG--GGSGICFEIAAQLARHGAHVAIM-GRRREVLDKAVAAL-RSEGLRAVG 354 L+GK ++TG G G+ E A A GA VAI R + ++ V L ++ G++A Sbjct: 18 LKGKVVVVTGASGPKGMGIEAARGCAEMGAAVAITYASRAQGAEENVKELEKTYGIKAKA 77 Query: 355 FQGDVRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVGTY 534 ++ V + E +++ V FG++D + A + D + + + V+++D GT+ Sbjct: 78 YKCQVDSYESCEKLVKDVVADFGQIDAFIANAGATADSGILDGSVEAWNHVVQVDLNGTF 137
>YGFF_ECOLI (P52037) Hypothetical oxidoreductase ygfF (EC 1.-.-.-)| Length = 247 Score = 43.9 bits (102), Expect = 3e-04 Identities = 33/120 (27%), Positives = 54/120 (45%), Gaps = 2/120 (1%) Frame = +1 Query: 202 ALITGGGSGICFEIAAQLARHGAHVAIMGRRR-EVLDKAVAALRSEGLRAVGFQGDVRNQ 378 AL+TGG GI A LA+ G VA+ ++ + + + G +A Q D+ ++ Sbjct: 4 ALVTGGSRGIGRATALLLAQEGYTVAVNYQQNLHAAQEVMNLITQAGGKAFVLQADISDE 63 Query: 379 EDAARVLASTVEHFGKLDILVNGAAGNFL-ASPEDLTPKGFRTVLEIDTVGTYTMCYEAL 555 + + +H L LVN A F + E+LT + VL + G + C EA+ Sbjct: 64 NQVVAMFTAIDQHDEPLAALVNNAGILFTQCTVENLTAERINRVLSTNVTGYFLCCREAV 123
>HCD2_BOVIN (O02691) 3-hydroxyacyl-CoA dehydrogenase type-2 (EC 1.1.1.35)| (3-hydroxyacyl-CoA dehydrogenase type II) (Type II HADH) (3-hydroxy-2-methylbutyryl-CoA dehydrogenase) (EC 1.1.1.178) Length = 260 Score = 43.9 bits (102), Expect = 3e-04 Identities = 34/125 (27%), Positives = 57/125 (45%), Gaps = 7/125 (5%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGD 366 ++G ALITGG SG+ A +L GA ++ + L G D Sbjct: 7 VKGLVALITGGASGLGLATAERLVGQGATAVLLDLPNSDGETQAKKL---GKSCAFAPAD 63 Query: 367 VRNQEDAARVLASTVEHFGKLDILVNGAAGNFLAS-------PEDLTPKGFRTVLEIDTV 525 V +++D L E FG++D+ VN AG +AS + T + F+ V+ ++ + Sbjct: 64 VTSEKDVQAALTLAREKFGRVDVAVN-CAGIAVASKTYNLKKSQAHTLEDFQRVINVNLI 122 Query: 526 GTYTM 540 GT+ + Sbjct: 123 GTFNV 127
>DHRS1_HUMAN (Q96LJ7) Dehydrogenase/reductase SDR family member 1 (EC 1.1.-.-)| Length = 313 Score = 43.9 bits (102), Expect = 3e-04 Identities = 33/90 (36%), Positives = 44/90 (48%), Gaps = 2/90 (2%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGD 366 + G+ ++TG GI IA QL + GA V I GR + L +S G + V D Sbjct: 5 MNGQVCVVTGASRGIGRGIALQLCKAGATVYITGRHLDTLRVVAQEAQSLGGQCVPVVCD 64 Query: 367 VRNQEDAARVLASTV--EHFGKLDILVNGA 450 +QE R L V E G+LD+LVN A Sbjct: 65 -SSQESEVRSLFEQVDREQQGRLDVLVNNA 93
>DHCA_PIG (Q28960) Carbonyl reductase [NADPH] 1 (EC 1.1.1.184)| (NADPH-dependent carbonyl reductase 1) (20-beta-hydroxysteroid dehydrogenase) (Prostaglandin-E(2) 9-reductase) (EC 1.1.1.189) (Prostaglandin 9-ketoreductase) (15-hydroxyprostaglandin dehydroge Length = 288 Score = 43.9 bits (102), Expect = 3e-04 Identities = 38/123 (30%), Positives = 58/123 (47%), Gaps = 3/123 (2%) Frame = +1 Query: 196 KAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKA-VAALRSEGLRAVGFQGDVR 372 + AL+TG GI F I L R A ++ R +A V L++EGL Q D+ Sbjct: 5 RVALVTGANKGIGFAIVRDLCRQFAGDVVLTARDVARGQAAVKQLQAEGLSPRFHQLDII 64 Query: 373 NQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDT--VGTYTMCY 546 + + + + +G LD+LVN AA F ++ TP + L + T +GT +C Sbjct: 65 DLQSIRALCDFLRKEYGGLDVLVNNAAIAF--QLDNPTPFHIQAELTMKTNFMGTRNVCT 122 Query: 547 EAL 555 E L Sbjct: 123 ELL 125
>FOX2_YEAST (Q02207) Peroxisomal hydratase-dehydrogenase-epimerase (HDE)| (Multifunctional beta-oxidation protein) (MFP) [Includes: 2-enoyl-CoA hydratase (EC 4.2.1.-); D-3-hydroxyacyl CoA dehydrogenase (EC 1.1.1.-)] Length = 900 Score = 43.9 bits (102), Expect = 3e-04 Identities = 30/126 (23%), Positives = 56/126 (44%), Gaps = 9/126 (7%) Frame = +1 Query: 190 RGKAALITGGGSGICFEIAAQLARHGAHVAI---------MGRRREVLDKAVAALRSEGL 342 + + +ITG G G+ A A GA V + G + D V ++ G Sbjct: 8 KDRVVVITGAGGGLGKVYALAYASRGAKVVVNDLGGTLGGSGHNSKAADLVVDEIKKAGG 67 Query: 343 RAVGFQGDVRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDT 522 AV V E+ +++ + ++ FG++D+L+N A S +T + F +V+++ Sbjct: 68 IAVANYDSVN--ENGEKIIETAIKEFGRVDVLINNAGILRDVSFAKMTEREFASVVDVHL 125 Query: 523 VGTYTM 540 G Y + Sbjct: 126 TGGYKL 131 Score = 32.0 bits (71), Expect = 1.2 Identities = 26/89 (29%), Positives = 43/89 (48%), Gaps = 1/89 (1%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREV-LDKAVAALRSEGLRAVGFQG 363 L K ++TG G G+ A AR+GA V + + + + + L EG A+ Sbjct: 320 LCNKVVVVTGAGGGLGKSHAIWFARYGAKVVVNDIKDPFSVVEEINKLYGEG-TAIPDSH 378 Query: 364 DVRNQEDAARVLASTVEHFGKLDILVNGA 450 DV +A ++ + + F ++DILVN A Sbjct: 379 DV--VTEAPLIIQTAISKFQRVDILVNNA 405
>RDH13_HUMAN (Q8NBN7) Retinol dehydrogenase 13 (EC 1.1.1.-)| Length = 331 Score = 43.9 bits (102), Expect = 3e-04 Identities = 30/118 (25%), Positives = 53/118 (44%), Gaps = 2/118 (1%) Frame = +1 Query: 193 GKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGL--RAVGFQGD 366 GK ++TG +GI + A +LAR G ++ + R E + A +R E L D Sbjct: 38 GKTVIVTGANTGIGKQTALELARRGGNIILACRDMEKCEAAAKDIRGETLNHHVNARHLD 97 Query: 367 VRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVGTYTM 540 + + + A +E ++DIL+N A + P T GF ++ +G + + Sbjct: 98 LASLKSIREFAAKIIEEEERVDILINNA--GVMRCPHWTTEDGFEMQFGVNHLGHFLL 153
>KDUD_DICD3 (Q05528) 2-deoxy-D-gluconate 3-dehydrogenase (EC 1.1.1.125)| (2-keto-3-deoxygluconate oxidoreductase) Length = 253 Score = 43.5 bits (101), Expect = 4e-04 Identities = 30/90 (33%), Positives = 45/90 (50%), Gaps = 2/90 (2%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMG--RRREVLDKAVAALRSEGLRAVGFQ 360 L+GK ALITG +G+ +A LA G + + +E ++K A G R + Sbjct: 8 LQGKVALITGCDTGLGQGMAVGLAEAGCDIVGVNIVEPKETIEKVTAV----GRRFLSLT 63 Query: 361 GDVRNQEDAARVLASTVEHFGKLDILVNGA 450 D+ + A ++ V FGK+DILVN A Sbjct: 64 ADMSDISGHAALVEKAVAEFGKVDILVNNA 93
>OXIR_STRLI (P35320) Probable oxidoreductase (EC 1.-.-.-)| Length = 297 Score = 43.5 bits (101), Expect = 4e-04 Identities = 36/118 (30%), Positives = 51/118 (43%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGD 366 L G+ A++TGG SG+ E LA GA V I R + + V + G V + Sbjct: 3 LTGRRAVVTGGASGLGAETVRALAAAGAEVTIATRHPQSAEPLVQEAAAAGAGRV--HAE 60 Query: 367 VRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVGTYTM 540 + D A V + G LDILV AG LTP G+ L + +G + + Sbjct: 61 ALDLSDVASVDSFARAWRGPLDILV-ANAGIMALPTRTLTPYGWEMQLATNYLGHFAL 117
>AYR1_YEAST (P40471) NADPH-dependent 1-acyldihydroxyacetone phosphate reductase| (EC 1.1.1.101) (Acylglycerone-phosphate reductase) (1-acyl DHAP reductase) (Acyl/alkyl DHAP reductase) (ADR) Length = 297 Score = 43.5 bits (101), Expect = 4e-04 Identities = 30/120 (25%), Positives = 52/120 (43%), Gaps = 2/120 (1%) Frame = +1 Query: 196 KAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGDVRN 375 K A++TG GI +E+ +LAR+G V RR E + + ++ ++ ++ D+ Sbjct: 10 KIAVVTGASGGIGYEVTKELARNGYLVYACARRLEPMAQLAIQFGNDSIKP--YKLDISK 67 Query: 376 QEDAARVLASTVEHF--GKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVGTYTMCYE 549 E+ + GKLD+L N A + D T +++ G MC E Sbjct: 68 PEEIVTFSGFLRANLPDGKLDLLYNNAGQSCTFPALDATDAAVEQCFKVNVFGHINMCRE 127
>YUXG_BACSU (P40747) Hypothetical oxidoreductase yuxG (EC 1.-.-.-) (ORF2)| Length = 689 Score = 43.5 bits (101), Expect = 4e-04 Identities = 37/112 (33%), Positives = 50/112 (44%), Gaps = 3/112 (2%) Frame = +1 Query: 160 TESPFRADVLRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALR--- 330 T +P A+ R K ALITGG GI + A G HV + E K + Sbjct: 417 TLAPPEAEFSR-KVALITGGAGGIGSAACRRFAAEGGHVIVADLNIEGAQKIAGEINDAY 475 Query: 331 SEGLRAVGFQGDVRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLT 486 +G RA+ + DV +ED +G +DI+VN AG +SP D T Sbjct: 476 GKG-RAMAVKMDVTKEEDVQSAFERAALAYGGIDIVVNN-AGLATSSPFDET 525
>CMTB_PSEPU (Q51977) 2,3-dihydroxy-2,3-dihydro-p-cumate dehydrogenase (EC| 1.3.1.58) (Biphenyl-2,3-dihydro-2,3-diol dehydrogenase) Length = 259 Score = 43.1 bits (100), Expect = 5e-04 Identities = 30/110 (27%), Positives = 49/110 (44%), Gaps = 1/110 (0%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQG- 363 L G+ A++TGG GI I +L GA V L L ++ A+ Sbjct: 11 LEGQVAVVTGGAHGIGLGIVERLLGLGARVTASDIDESGLSLLCERLAAKHADAIAVHAA 70 Query: 364 DVRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLE 513 D+ ++ A + + VE FG + ILVN A G + + TP+ + ++ Sbjct: 71 DLSEEQGAQGLHRAAVERFGSVQILVNCAGGGVIRPFLEHTPETLKATID 120
>YNU3_YEAST (P40163) Very hypothetical 22.4 kDa protein in SPX18-SPX19| intergenic region Length = 203 Score = 43.1 bits (100), Expect = 5e-04 Identities = 37/131 (28%), Positives = 55/131 (41%), Gaps = 5/131 (3%) Frame = -1 Query: 557 FRAS*HIVYVPTVSISRTVRNPLGVRSSGDARKLPAAPLTRMSSLPKCSTVDASTLAASS 378 F+ + ++ +P+ S+S T G R + K PAAP S LP STV + + S Sbjct: 10 FKHALAVLKLPSKSMSTTDLKAFGERFAKSHTKFPAAPAMTKSILPNFSTVFLTAFSTCS 69 Query: 377 WLRTSP*KPTARRPSEXXX-----XXXXXXXXXXRPMMATWAPWRASWAAISKQMPEPPP 213 LRTS A+ S P +A P R + ++ + PP Sbjct: 70 KLRTST-FAIAKTASLSFANCEIPFAACSVLSWSLPTIAALQPRRTKASVCTRHIVPAPP 128 Query: 212 VISAALPLSTS 180 V +A LPL+ S Sbjct: 129 VTNATLPLNKS 139
>TS2_MAIZE (P50160) Sex determination protein tasselseed-2| Length = 336 Score = 42.7 bits (99), Expect = 7e-04 Identities = 36/99 (36%), Positives = 48/99 (48%), Gaps = 2/99 (2%) Frame = +1 Query: 160 TESPFRADVLRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEG 339 T P R D GK A++TGG GI I A+HGA V I ++ D A AL S Sbjct: 47 TPMPKRLD---GKVAIVTGGARGIGEAIVRLFAKHGARVVI----ADIDDAAGEALASAL 99 Query: 340 LRAVGF-QGDVRNQEDAARVLA-STVEHFGKLDILVNGA 450 V F + DV ++D R + + H G+LD+ N A Sbjct: 100 GPQVSFVRCDVSVEDDVRRAVDWALSRHGGRLDVYCNNA 138
>BUDC_KLETE (Q04520) Acetoin(diacetyl) reductase (EC 1.1.1.5) (Acetoin| dehydrogenase) (AR) (Meso-2,3-butanediol dehydrogenase) Length = 241 Score = 42.7 bits (99), Expect = 7e-04 Identities = 26/85 (30%), Positives = 38/85 (44%) Frame = +1 Query: 196 KAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGDVRN 375 K AL+TG G GI IA +L + G VAI A + G RAV + DV Sbjct: 3 KVALVTGAGQGIGKAIALRLVKDGFAVAIADYNDATATAVAAEINQAGGRAVAIKVDVSR 62 Query: 376 QEDAARVLASTVEHFGKLDILVNGA 450 ++ + + G +++VN A Sbjct: 63 RDQVFAAVEQARKALGGFNVIVNNA 87
>SDH_AGRT5 (Q8U8I2) Serine 3-dehydrogenase (EC 1.1.1.276)| Length = 249 Score = 42.7 bits (99), Expect = 7e-04 Identities = 33/118 (27%), Positives = 57/118 (48%), Gaps = 1/118 (0%) Frame = +1 Query: 205 LITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGDVRNQED 384 LITG SG A + + G V GRR E L+ A+AA + + F D+ +++ Sbjct: 6 LITGATSGFGQATARRFVKEGWKVIGTGRRAERLE-ALAAELGQAFHGIAF--DITDEDA 62 Query: 385 AARVLASTVEHFGKLDILVNGAAGNFLASP-EDLTPKGFRTVLEIDTVGTYTMCYEAL 555 + LA+ + F +DILVN A +P + K ++T+++ + G + + L Sbjct: 63 TEKALAALPDGFRDIDILVNNAGLALGTAPAPQVALKDWQTMVDTNITGLLNITHHLL 120
>FABG_THEMA (Q9X248) 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100)| (3-ketoacyl-acyl carrier protein reductase) Length = 246 Score = 42.7 bits (99), Expect = 7e-04 Identities = 30/90 (33%), Positives = 45/90 (50%), Gaps = 2/90 (2%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGL--RAVGFQ 360 L GK LITG SGI A+ GA V +E LD V +EGL + + Sbjct: 3 LEGKVCLITGAASGIGKATTLLFAQEGATVIAGDISKENLDSLVK--EAEGLPGKVDPYV 60 Query: 361 GDVRNQEDAARVLASTVEHFGKLDILVNGA 450 +V +++ V+ V+ +G++D+LVN A Sbjct: 61 LNVTDRDQIKEVVEKVVQKYGRIDVLVNNA 90
>DHCA_RAT (P47727) Carbonyl reductase [NADPH] 1 (EC 1.1.1.184)| (NADPH-dependent carbonyl reductase 1) Length = 276 Score = 42.4 bits (98), Expect = 9e-04 Identities = 37/121 (30%), Positives = 55/121 (45%), Gaps = 3/121 (2%) Frame = +1 Query: 202 ALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLD-KAVAALRSEGLRAVGFQGDVRNQ 378 AL+TG GI F I L R ++ R E +AV L++EGL Q D+ N Sbjct: 7 ALVTGANKGIGFAIVRDLCRKFLGDVVLTARDESRGHEAVKQLQTEGLSPRFHQLDIDNP 66 Query: 379 EDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDT--VGTYTMCYEA 552 + + ++ +G L++LVN A F D TP + + + T GT +C E Sbjct: 67 QSIRALRDFLLQEYGGLNVLVNNAGIAF--KVVDPTPFHIQAEVTMKTNFFGTQDVCKEL 124 Query: 553 L 555 L Sbjct: 125 L 125
>OXIR_STRAT (Q03326) Probable oxidoreductase (EC 1.-.-.-)| Length = 298 Score = 42.4 bits (98), Expect = 9e-04 Identities = 36/118 (30%), Positives = 51/118 (43%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGD 366 L G+ A++TGG SG+ E LA GA V + RR + V L + G A + Sbjct: 3 LTGRRAVVTGGASGLGAETVRALAAAGAEVTVATRRPLSAEPLVQELAAAG-GAGRVTAE 61 Query: 367 VRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVGTYTM 540 + D A V + G LDILV AG L P G+ L + +G + + Sbjct: 62 ALDLSDPASVESFARAWRGPLDILV-ANAGIMALPTRTLAPNGWEMQLATNYLGHFAL 118
>EPHD_MYCTU (P66777) Probable oxidoreductase ephD (EC 1.-.-.-)| Length = 592 Score = 42.4 bits (98), Expect = 9e-04 Identities = 35/116 (30%), Positives = 47/116 (40%), Gaps = 4/116 (3%) Frame = +1 Query: 208 ITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGDVRNQEDA 387 +TG GSGI E A AR GA + I + A + + G A + DV + E Sbjct: 329 VTGAGSGIGRETALAFAREGAEIVISDIDEATVKDTAAEIAARGGIAYPYVLDVSDAEAV 388 Query: 388 ARVLASTVEHFGKLDILVN----GAAGNFLASPEDLTPKGFRTVLEIDTVGTYTMC 543 G DI+VN G AG FL +P + F VL ++ G C Sbjct: 389 EAFAERVSAEHGVPDIVVNNAGIGQAGRFLDTPAE----QFDRVLAVNLGGVVNGC 440
>EPHD_MYCBO (P66778) Probable oxidoreductase ephD (EC 1.-.-.-)| Length = 592 Score = 42.4 bits (98), Expect = 9e-04 Identities = 35/116 (30%), Positives = 47/116 (40%), Gaps = 4/116 (3%) Frame = +1 Query: 208 ITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGDVRNQEDA 387 +TG GSGI E A AR GA + I + A + + G A + DV + E Sbjct: 329 VTGAGSGIGRETALAFAREGAEIVISDIDEATVKDTAAEIAARGGIAYPYVLDVSDAEAV 388 Query: 388 ARVLASTVEHFGKLDILVN----GAAGNFLASPEDLTPKGFRTVLEIDTVGTYTMC 543 G DI+VN G AG FL +P + F VL ++ G C Sbjct: 389 EAFAERVSAEHGVPDIVVNNAGIGQAGRFLDTPAE----QFDRVLAVNLGGVVNGC 440
>RDH12_BOVIN (P59837) Retinol dehydrogenase 12 (EC 1.1.1.-) (Double substrate| specificity short chain dehydrogenase/reductase 2) Length = 316 Score = 42.0 bits (97), Expect = 0.001 Identities = 43/137 (31%), Positives = 60/137 (43%), Gaps = 13/137 (9%) Frame = +1 Query: 175 RADV-LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAV 351 R DV L GK +ITG +GI E A +LAR GA V I R+VL AA Sbjct: 32 RTDVQLFGKVVVITGANTGIGKETARELARRGARVYI--ACRDVLKGESAASE------- 82 Query: 352 GFQGDVRNQEDAARVL----ASTVEHFG--------KLDILVNGAAGNFLASPEDLTPKG 495 Q D +N + R L ++ F +L IL+N A + P T G Sbjct: 83 -IQADTKNSQVLVRKLDLSDTKSIRAFAEGFLAEEKQLHILINNA--GVMLCPYSKTADG 139 Query: 496 FRTVLEIDTVGTYTMCY 546 F T L ++ +G + + + Sbjct: 140 FETHLAVNHLGHFLLTH 156
>FABG_MYCTU (P0A5Y4) 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100)| (3-ketoacyl-acyl carrier protein reductase) Length = 247 Score = 42.0 bits (97), Expect = 0.001 Identities = 32/119 (26%), Positives = 54/119 (45%) Frame = +1 Query: 196 KAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGDVRN 375 ++ L+TGG GI IA +LA G VA+ R + +GL G + DV + Sbjct: 16 RSVLVTGGNRGIGLAIAQRLAADGHKVAVTHR---------GSGAPKGL--FGVECDVTD 64 Query: 376 QEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVGTYTMCYEA 552 + R + EH G +++LV+ A + A +T + F V+ + G + + A Sbjct: 65 SDAVDRAFTAVEEHQGPVEVLVSNAGLSADAFLMRMTEEKFEKVINANLTGAFRVAQRA 123
>FABG_MYCBO (P0A5Y5) 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100)| (3-ketoacyl-acyl carrier protein reductase) Length = 247 Score = 42.0 bits (97), Expect = 0.001 Identities = 32/119 (26%), Positives = 54/119 (45%) Frame = +1 Query: 196 KAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGDVRN 375 ++ L+TGG GI IA +LA G VA+ R + +GL G + DV + Sbjct: 16 RSVLVTGGNRGIGLAIAQRLAADGHKVAVTHR---------GSGAPKGL--FGVECDVTD 64 Query: 376 QEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVGTYTMCYEA 552 + R + EH G +++LV+ A + A +T + F V+ + G + + A Sbjct: 65 SDAVDRAFTAVEEHQGPVEVLVSNAGLSADAFLMRMTEEKFEKVINANLTGAFRVAQRA 123
>DHB13_HUMAN (Q7Z5P4) 17-beta hydroxysteroid dehydrogenase 13 precursor (EC| 1.1.-.-) (Short-chain dehydrogenase/reductase 9) Length = 300 Score = 42.0 bits (97), Expect = 0.001 Identities = 28/122 (22%), Positives = 53/122 (43%) Frame = +1 Query: 169 PFRADVLRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRA 348 P R + G+ LITG G GI + + A+ + + + + +++ A R G+ A Sbjct: 28 PQRRKSVAGEIVLITGAGHGIGRQTTYEFAKRQSILVLWDINKRGVEETAAECRKLGVTA 87 Query: 349 VGFQGDVRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVG 528 + D N+E+ R L + G + I+VN A + A + E++ +G Sbjct: 88 HAYVVDCSNREEIYRSLNQVKKEVGDVTIVVNNAGTVYPADLLSTKDEEITKTFEVNILG 147 Query: 529 TY 534 + Sbjct: 148 HF 149
>ERYA3_SACER (Q03133) Erythronolide synthase, modules 5 and 6 (EC 2.3.1.94) (ORF| 3) (6-deoxyerythronolide B synthase III) (DEBS 3) Length = 3171 Score = 42.0 bits (97), Expect = 0.001 Identities = 39/119 (32%), Positives = 57/119 (47%), Gaps = 7/119 (5%) Frame = +1 Query: 205 LITGGGSGICFEIAAQLARHGA-HVAIMGRRREVLDKAVAALRSEGLRAVG-----FQGD 366 L+TGG GI +A LAR GA H+ ++GRR D A+ E L A+G D Sbjct: 1119 LVTGGTGGIGAHLARWLARSGAEHLVLLGRRG--ADAPGASELREELTALGTGVTIAACD 1176 Query: 367 VRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASP-EDLTPKGFRTVLEIDTVGTYTM 540 V ++ VLA+ G+ V AAG ++P +DLT F + ++ GT + Sbjct: 1177 VADRARLEAVLAAEAAAEGRTVSAVMHAAGVSTSTPLDDLTEAEFTEIADVKVRGTVNL 1235 Score = 30.0 bits (66), Expect = 4.6 Identities = 22/70 (31%), Positives = 34/70 (48%), Gaps = 4/70 (5%) Frame = +1 Query: 202 ALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSE----GLRAVGFQGDV 369 AL+TGG + +A LAR G ++ RR V A A L +E G + DV Sbjct: 2558 ALVTGGTGALGGHVARHLARCGVEDLVLVSRRGVDAPAAAELEAELVALGPKTTITACDV 2617 Query: 370 RNQEDAARVL 399 ++E +++L Sbjct: 2618 ADREQLSKLL 2627
>FABG_VIBCH (Q9KQH7) 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100)| (3-ketoacyl-acyl carrier protein reductase) Length = 244 Score = 42.0 bits (97), Expect = 0.001 Identities = 32/88 (36%), Positives = 37/88 (42%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGD 366 L GK AL+TG GI IA LA GA V L G G + Sbjct: 3 LEGKVALVTGASRGIGKAIAELLAERGAKVIGTATSESGAQAISDYLGDNGK---GMALN 59 Query: 367 VRNQEDAARVLASTVEHFGKLDILVNGA 450 V N E VL + + FG +DILVN A Sbjct: 60 VTNPESIEAVLKAITDEFGGVDILVNNA 87
>DCXR_MESAU (Q91XV4) L-xylulose reductase (EC 1.1.1.10) (XR)| (Dicarbonyl/L-xylulose reductase) (Sperm antigen P26h) Length = 244 Score = 42.0 bits (97), Expect = 0.001 Identities = 34/104 (32%), Positives = 49/104 (47%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGD 366 L G+ AL+TG G GI L GAHV + R + LD V+ G+ V D Sbjct: 5 LAGRRALVTGAGKGIGRSTVLALQAAGAHVVAVSRTQADLDSLVS--ECPGVETVCV--D 60 Query: 367 VRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGF 498 + + E + L+S G +D+LVN AA L ++T + F Sbjct: 61 LADWEATEQALSSV----GPVDLLVNNAAVALLQPFLEVTKEAF 100
>WWOX_BRARE (Q803A8) WW domain-containing oxidoreductase (EC 1.1.1.-)| Length = 412 Score = 42.0 bits (97), Expect = 0.001 Identities = 36/123 (29%), Positives = 54/123 (43%), Gaps = 5/123 (4%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRA-----V 351 L K ++TG SGI FE A A HGAHV + R + KA + + E +A Sbjct: 119 LSDKVIIVTGANSGIGFETARSFALHGAHVILACRNQSRASKAASLIMGEWSKARVEVLP 178 Query: 352 GFQGDVRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVGT 531 +R+ A + +T L +LV AA + P LT GF + +I +G Sbjct: 179 LDLASLRSVRQFAELFKATKL---PLHVLVCNAA--VCSQPWRLTEDGFESTFQICHLGH 233 Query: 532 YTM 540 + + Sbjct: 234 FLL 236
>MAS12_AGRRH (P50201) Agropine synthesis reductase (EC 1.-.-.-)| Length = 430 Score = 42.0 bits (97), Expect = 0.001 Identities = 35/121 (28%), Positives = 56/121 (46%), Gaps = 1/121 (0%) Frame = +1 Query: 181 DVLRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQ 360 ++ + LI+G GI IA L HG +++ RR + L+ A +SE L F Sbjct: 195 EIHQSPVILISGPSRGIGKAIAENLIAHGYRMSLGARRVKDLESAFGP-QSEWLHYARF- 252 Query: 361 GDVRNQEDAARVLASTVEHFGKLDILVNGA-AGNFLASPEDLTPKGFRTVLEIDTVGTYT 537 D + + A + + VE FG++D L+N A G + +D+ K F I+ V Sbjct: 253 -DAEDNDTMAAWVTAAVEKFGRIDGLINNAGCGEPVNLEKDIDYKQFHRQWHINCVAPLR 311 Query: 538 M 540 M Sbjct: 312 M 312
>HCDS_XANP2 (Q56841) 2-(S)-hydroxypropyl-CoM dehydrogenase (EC 1.1.1.269)| (S-HPCDH) (Aliphatic epoxide carboxylation component IV) Length = 249 Score = 41.6 bits (96), Expect = 0.002 Identities = 33/124 (26%), Positives = 50/124 (40%) Frame = +1 Query: 184 VLRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQG 363 +L + ITGG +GI +A R GA VA++ R +A A G A G Sbjct: 1 MLDAEVIAITGGAAGIGLAVAHAAIRAGARVALIDRDGACAQRAAAEF---GAAAWGVGA 57 Query: 364 DVRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVGTYTMC 543 DV ++ +A G L LVN A S + + ++ ++ GT+ Sbjct: 58 DVTDEAAITAAMAGAQRALGPLTGLVNNAGIAGFGSVHATEVETWSRIMAVNVTGTFLAS 117 Query: 544 YEAL 555 AL Sbjct: 118 KAAL 121
>HDHA_CLOSO (P50200) NADP-dependent 7-alpha-hydroxysteroid dehydrogenase (EC| 1.1.1.-) (Bile acid 7-dehydroxylase) (7-alpha-HSDH) Length = 267 Score = 41.6 bits (96), Expect = 0.002 Identities = 28/86 (32%), Positives = 43/86 (50%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGD 366 L K AL+T GI A +LA++GA V + RR E + + EGL D Sbjct: 4 LENKVALVTSATRGIGLASAIKLAQNGAIVYMGVRRLEATQEICDKYKEEGLILKPVFFD 63 Query: 367 VRNQEDAARVLASTVEHFGKLDILVN 444 N + ++ + +++ GK+DILVN Sbjct: 64 AYNIDIYKEMIDTIIKNEGKIDILVN 89
>RDH12_MOUSE (Q8BYK4) Retinol dehydrogenase 12 (EC 1.1.1.-)| Length = 316 Score = 41.2 bits (95), Expect = 0.002 Identities = 37/124 (29%), Positives = 55/124 (44%), Gaps = 6/124 (4%) Frame = +1 Query: 193 GKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEG------LRAVG 354 GK +ITG +GI E A +LAR GA V I R + A + +R++ +R + Sbjct: 39 GKVVVITGANTGIGKETARELARRGARVYIACRDVLKGESAASEIRADTKNSQVLVRKLD 98 Query: 355 FQGDVRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVGTY 534 + A R LA KL IL+N A + P T GF T ++ +G + Sbjct: 99 LSDTKSIRAFAERFLAEE----KKLHILINNA--GVMMCPYSKTTDGFETHFGVNHLGHF 152 Query: 535 TMCY 546 + Y Sbjct: 153 LLTY 156
>FVT1_MOUSE (Q6GV12) 3-ketodihydrosphingosine reductase precursor (EC| 1.1.1.102) (3-dehydrosphinganine reductase) (KDS reductase) (Follicular variant translocation protein 1) (FVT-1) Length = 332 Score = 41.2 bits (95), Expect = 0.002 Identities = 30/120 (25%), Positives = 54/120 (45%), Gaps = 5/120 (4%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLR----AVG 354 L G ++TGG SGI IA + + GA + ++ R + L +A + + + Sbjct: 30 LPGAHVVVTGGSSGIGKCIAIECYKQGAFITLVARNEDKLLQAKKDIEKHSINDKQVVLC 89 Query: 355 FQGDV-RNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVGT 531 DV ++ V+ E G +D+LVN A + E+L F ++ I+ +G+ Sbjct: 90 ISVDVSQDYNQVENVIKQAQEKLGPVDMLVNCAGTSMSGKFEELEVSSFEKLMSINYLGS 149
>RDH14_MOUSE (Q9ERI6) Retinol dehydrogenase 14 (EC 1.1.1.-) (Alcohol| dehydrogenase PAN2) Length = 334 Score = 41.2 bits (95), Expect = 0.002 Identities = 37/131 (28%), Positives = 58/131 (44%), Gaps = 12/131 (9%) Frame = +1 Query: 184 VLRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQG 363 ++ GK LITG SG+ AA+L R GA V + R R ++A LR E +A G Sbjct: 41 LMHGKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRQELCQAGGAGP 100 Query: 364 D------VRNQEDAARVLA------STVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTV 507 D V + D A + + ++ +LD+L+N A P T GF Sbjct: 101 DGTDGQLVVKELDLASLRSVRAFCQELLQEEPRLDVLINNA--GVFHCPYTKTEDGFEMQ 158 Query: 508 LEIDTVGTYTM 540 ++ +G + + Sbjct: 159 FGVNHLGHFLL 169
>FABG_AQUAE (O67610) 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100)| (3-ketoacyl-acyl carrier protein reductase) Length = 248 Score = 40.8 bits (94), Expect = 0.003 Identities = 36/125 (28%), Positives = 59/125 (47%), Gaps = 2/125 (1%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVA--ALRSEGLRAVGFQ 360 L+GK +L+TG GI IA +LA G+ V I G E KAVA G++A G + Sbjct: 5 LQGKVSLVTGSTRGIGRAIAEKLASAGSTVIITGTSGE-RAKAVAEEIANKYGVKAHGVE 63 Query: 361 GDVRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVGTYTM 540 ++ ++E + +DILVN A ++ + VL+++ GT+ + Sbjct: 64 MNLLSEESINKAFEEIYNLVDGIDILVNNAGITRDKLFLRMSLLDWEEVLKVNLTGTFLV 123 Query: 541 CYEAL 555 +L Sbjct: 124 TQNSL 128
>Y3106_PSEAE (Q51576) Putative oxidoreductase PA3106 (EC 1.-.-.-)| Length = 255 Score = 40.8 bits (94), Expect = 0.003 Identities = 38/115 (33%), Positives = 52/115 (45%) Frame = +1 Query: 193 GKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGDVR 372 GK AL+TG GI I+A L G V + RE + AL G A DV Sbjct: 10 GKVALVTGAARGIGLGISAWLIAEGWQVVLADNDRERGARVAEAL---GEHAWFVAMDVA 66 Query: 373 NQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVGTYT 537 + A +A + FG+LD LV AA +A+P + T LE ++G +T Sbjct: 67 QEGQVAMSVAEVLGQFGRLDGLVCNAA---IANPRN-------TPLEALSLGEWT 111
>PKSL_BACSU (Q05470) Putative polyketide synthase pksL (PKS)| Length = 4538 Score = 40.8 bits (94), Expect = 0.003 Identities = 25/86 (29%), Positives = 44/86 (51%), Gaps = 4/86 (4%) Frame = +1 Query: 205 LITGGGSGICFEIAAQLARHGAHVAIMGRRREVLD----KAVAALRSEGLRAVGFQGDVR 372 LITGG G+ F A ++A ++ R LD K + AL+ G++A+ Q D+ Sbjct: 1524 LITGGAGGLGFIFATEIANQTNDAVVILTGRSPLDERKKKKLKALQKLGIQAIYRQADLA 1583 Query: 373 NQEDAARVLASTVEHFGKLDILVNGA 450 +++ +L T +G LD +++ A Sbjct: 1584 DKQTVDALLKETQNVYGDLDGIIHSA 1609
>LIMC_RHOER (Q9RA05) Carveol dehydrogenase (EC 1.1.1.275) ((+)-trans-carveol| dehydrogenase) (CDH) Length = 277 Score = 40.8 bits (94), Expect = 0.003 Identities = 32/129 (24%), Positives = 55/129 (42%), Gaps = 13/129 (10%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREV------------LDKAVAALR 330 + G+ ALITG G A +LA GA V ++ +V LD+ + Sbjct: 4 VEGQVALITGAARGQGRSHAIKLAEEGADVILVDVPNDVVDIGYPLGTADELDQTAKDVE 63 Query: 331 SEGLRAVGFQGDVRNQEDAARVLASTVEHFGKLDIL-VNGAAGNFLASPEDLTPKGFRTV 507 + G +A+ DVR+ E + V G+LDI+ N + D+ +R + Sbjct: 64 NLGRKAIVIHADVRDLESLTAEVDRAVSTLGRLDIVSANAGIASVPFLSHDIPDNTWRQM 123 Query: 508 LEIDTVGTY 534 ++I+ G + Sbjct: 124 IDINLTGVW 132
>Y4VI_RHISN (Q53217) Putative short-chain type dehydrogenase/reductase y4vI (EC| 1.-.-.-) Length = 548 Score = 40.8 bits (94), Expect = 0.003 Identities = 29/119 (24%), Positives = 54/119 (45%) Frame = +1 Query: 196 KAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGDVRN 375 + ++ GG +G+ IA + A +G V I E K L G + + + D Sbjct: 278 RTVIVMGGATGVGAAIARRFAENGDTVVIADGDGEEAVKLAGLL---GDKHLSRRVDRTV 334 Query: 376 QEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVGTYTMCYEA 552 + + + E FG LD+ VNG + + E+ +P+ + +L+++ G +T EA Sbjct: 335 ETEVVSLFEELRERFGHLDVFVNGMNEILVPNTEE-SPEVLKRILDVNLTGAFTCVREA 392
>TSC10_CRYNE (Q5KEJ9) 3-ketodihydrosphingosine reductase TSC10 (EC 1.1.1.102)| (3-dehydrosphinganine reductase) (KDS reductase) Length = 335 Score = 40.8 bits (94), Expect = 0.003 Identities = 23/60 (38%), Positives = 33/60 (55%) Frame = +1 Query: 190 RGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGDV 369 RGK ITGG SG+ +A +L + GAHV I+GR + + V E L+A+ G + Sbjct: 34 RGKHCYITGGSSGLGKALAERLVKQGAHVTIVGRDSKKAEGVV-----EELKAIAAPGQI 88
>KDUD_BACSU (P50842) 2-deoxy-D-gluconate 3-dehydrogenase (EC 1.1.1.125)| (2-keto-3-deoxygluconate oxidoreductase) Length = 254 Score = 40.8 bits (94), Expect = 0.003 Identities = 34/111 (30%), Positives = 54/111 (48%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGD 366 L+GK AL+TG G+GI IA LA GA + I L + + EG F D Sbjct: 10 LKGKTALVTGPGTGIGQGIAKALAGAGADI-IGTSHTSSLSETQQLVEQEGRIFTSFTLD 68 Query: 367 VRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEID 519 + ++ +A + A+ + ++DILVN A ED + ++ VL ++ Sbjct: 69 M-SKPEAIKDSAAELFENRQIDILVNNAGIIHREKAEDFPEENWQHVLNVN 118
>DHB8_PIG (Q9XT00) Estradiol 17-beta-dehydrogenase 8 (EC 1.1.1.62)| (17-beta-HSD 8) (17-beta-hydroxysteroid dehydrogenase 8) (Ke6 protein) (Ke-6) Length = 259 Score = 40.4 bits (93), Expect = 0.003 Identities = 31/97 (31%), Positives = 40/97 (41%), Gaps = 7/97 (7%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLR------- 345 LR AL+TG GSGI ++ +LA GA VA + V L G Sbjct: 7 LRSALALVTGAGSGIGRAVSVRLAAEGAAVAACDLDGAAAQETVQLLGGPGSEKGAPSGP 66 Query: 346 AVGFQGDVRNQEDAARVLASTVEHFGKLDILVNGAAG 456 FQ DV E A R+L +F + +V AG Sbjct: 67 MAAFQADVSEAETARRLLEQVQAYFFRPPSVVVSCAG 103
>DHB8_CANFA (Q5TJF5) Estradiol 17-beta-dehydrogenase 8 (EC 1.1.1.62)| (17-beta-HSD 8) (17-beta-hydroxysteroid dehydrogenase 8) Length = 259 Score = 40.4 bits (93), Expect = 0.003 Identities = 34/104 (32%), Positives = 44/104 (42%), Gaps = 7/104 (6%) Frame = +1 Query: 166 SPFRADVLRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLR 345 SP R LR AL+TG GSGI ++ +LA+ GA VA R + V L +G Sbjct: 3 SPLR---LRSALALVTGAGSGIGRAVSVRLAKEGATVAACDLDRAAACETVWLLGGQGSE 59 Query: 346 AV-------GFQGDVRNQEDAARVLASTVEHFGKLDILVNGAAG 456 V FQ DV R+L F + +V AG Sbjct: 60 KVAPGGAHTAFQADVSEAGAVRRLLEQVQACFSRPPSVVVSCAG 103
>YCIK_ECOLI (P31808) Hypothetical oxidoreductase yciK (EC 1.-.-.-)| Length = 252 Score = 40.4 bits (93), Expect = 0.003 Identities = 30/126 (23%), Positives = 60/126 (47%), Gaps = 4/126 (3%) Frame = +1 Query: 175 RADVLRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSE-GLRAV 351 + D+L + L+TG GI E A AR+GA V ++GR E L + + + E G + Sbjct: 6 KQDLLNDRIILVTGASDGIGREAAMTYARYGATVILLGRNEEKLRQVASHINEETGRQPQ 65 Query: 352 GFQGDVR--NQEDAARVLASTVEHFGKLD-ILVNGAAGNFLASPEDLTPKGFRTVLEIDT 522 F D+ E+ ++ ++ +LD +L N + + P+ ++ V++++ Sbjct: 66 WFILDLLTCTSENCQQLAQRIAVNYPRLDGVLHNAGLLGDVCPMSEQNPQVWQDVMQVNV 125 Query: 523 VGTYTM 540 T+ + Sbjct: 126 NATFML 131
>FABI_SYNY3 (P73016) Enoyl-[acyl-carrier-protein] reductase [NADH] (EC 1.3.1.9)| (NADH-dependent enoyl-ACP reductase) Length = 258 Score = 40.4 bits (93), Expect = 0.003 Identities = 35/124 (28%), Positives = 54/124 (43%), Gaps = 12/124 (9%) Frame = +1 Query: 187 LRGKAALITG--GGSGICFEIAAQLARHGAHVAI--MGRRREVLDKAVAALRSEGLRAVG 354 L GK A +TG I + IA QL + GA + + + + +K V L + Sbjct: 4 LSGKHAFVTGIANNRSIAWGIAQQLHQAGAEIGVSYLPDEKGRFEKKVRELTEPLHPTLV 63 Query: 355 FQGDVRNQEDAARVLASTVEHFGKLDILV--------NGAAGNFLASPEDLTPKGFRTVL 510 GDV++ + S E +GKLDIL+ +G GN+ D+ + F + Sbjct: 64 LPGDVQDDAQVDALFHSVKEKWGKLDILIHCLAFADKSGLTGNY----TDIPKEAFSQAM 119 Query: 511 EIDT 522 EI T Sbjct: 120 EIST 123
>DHC3_HUMAN (O75828) Carbonyl reductase [NADPH] 3 (EC 1.1.1.184)| (NADPH-dependent carbonyl reductase 3) Length = 276 Score = 40.4 bits (93), Expect = 0.003 Identities = 36/123 (29%), Positives = 54/123 (43%), Gaps = 3/123 (2%) Frame = +1 Query: 196 KAALITGGGSGICFEIAAQLARH-GAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGDVR 372 + AL+TG GI IA +L R V + R AV L++EGL Q D+ Sbjct: 5 RVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAEGLSPRFHQLDID 64 Query: 373 NQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDT--VGTYTMCY 546 + + + + +G L++LVN AA F +D P + + + T T MC Sbjct: 65 DLQSIRALRDFLRKEYGGLNVLVNNAAVAF--KSDDPMPFDIKAEMTLKTNFFATRNMCN 122 Query: 547 EAL 555 E L Sbjct: 123 ELL 125
>FVT1_HUMAN (Q06136) 3-ketodihydrosphingosine reductase precursor (EC| 1.1.1.102) (3-dehydrosphinganine reductase) (KDS reductase) (Follicular variant translocation protein 1) (FVT-1) Length = 332 Score = 40.0 bits (92), Expect = 0.004 Identities = 31/120 (25%), Positives = 53/120 (44%), Gaps = 5/120 (4%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLR----AVG 354 L G ++TGG SGI IA + + GA + ++ R + L +A + + + Sbjct: 30 LPGAHVVVTGGSSGIGKCIAIECYKQGAFITLVARNEDKLLQAKKEIEMHSINDKQVVLC 89 Query: 355 FQGDV-RNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVGT 531 DV ++ V+ E G +D+LVN A EDL F ++ I+ +G+ Sbjct: 90 ISVDVSQDYNQVENVIKQAQEKLGPVDMLVNCAGMAVSGKFEDLEVSTFERLMSINYLGS 149
>DHRS7_MOUSE (Q9CXR1) Dehydrogenase/reductase SDR family member 7 precursor (EC| 1.1.-.-) (Retinal short-chain dehydrogenase/reductase 4) Length = 338 Score = 40.0 bits (92), Expect = 0.004 Identities = 26/115 (22%), Positives = 53/115 (46%), Gaps = 4/115 (3%) Frame = +1 Query: 208 ITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEG----LRAVGFQGDVRN 375 +TG SGI E+A QL++ G + + RR + L++ G + D+ + Sbjct: 55 VTGASSGIGEELAFQLSKLGVSLVLSARRAQELERVKRRCLENGNLKEKDILVLPLDLTD 114 Query: 376 QEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVGTYTM 540 + ++ FGK+DILVN + + + F+ ++ ++ +GT ++ Sbjct: 115 TSSHEAATKAVLQEFGKIDILVNNGGRSQRSLVLETNLDVFKELINLNYIGTVSL 169
>PHBB_ZOORA (P23238) Acetoacetyl-CoA reductase (EC 1.1.1.36)| Length = 241 Score = 40.0 bits (92), Expect = 0.004 Identities = 33/117 (28%), Positives = 50/117 (42%) Frame = +1 Query: 196 KAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGDVRN 375 + AL+TGG GI I+ L G VA D A ++E AV ++ DV + Sbjct: 3 RVALVTGGSRGIGAAISIALKAAGYKVAASYAGN---DDAAKPFKAETGIAV-YKWDVSS 58 Query: 376 QEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVGTYTMCY 546 E +A G +D+LVN A A +TP + V+ + G + M + Sbjct: 59 YEACVEGIAKVEADLGPIDVLVNNAGITKDAMFHKMTPDQWNAVINTNLTGLFNMTH 115
>FABG_RICPR (P50941) 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100)| (3-ketoacyl-acyl carrier protein reductase) Length = 241 Score = 40.0 bits (92), Expect = 0.004 Identities = 36/123 (29%), Positives = 56/123 (45%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGD 366 L GK +LITG SGI IA L + G+ V I G E L AL+ V + Sbjct: 4 LTGKTSLITGASSGIGSAIARLLHKLGSKVIISGSNEEKLKSLGNALKDNYTIEV---CN 60 Query: 367 VRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVGTYTMCY 546 + N+E+ + +++ T LDILV A + + F V++I+ + + Sbjct: 61 LANKEECSNLISKT----SNLDILVCNAGITSDTLAIRMKDQDFDKVIDINLKANFILNR 116 Query: 547 EAL 555 EA+ Sbjct: 117 EAI 119
>DHCA_PONPY (Q5RCU5) Carbonyl reductase [NADPH] 1 (EC 1.1.1.184)| (NADPH-dependent carbonyl reductase 1) Length = 276 Score = 40.0 bits (92), Expect = 0.004 Identities = 37/121 (30%), Positives = 53/121 (43%), Gaps = 3/121 (2%) Frame = +1 Query: 202 ALITGGGSGICFEIAAQLAR-HGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGDVRNQ 378 AL+TGG GI I L R V + R AV L++EGL Q D+ + Sbjct: 7 ALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVARGQAAVQQLQAEGLSPRFHQLDIDDL 66 Query: 379 EDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDT--VGTYTMCYEA 552 + + + +G LD+LVN A F + D TP + + + T GT +C E Sbjct: 67 QSIRALRDFLRKEYGGLDVLVNNAGIAFKVA--DPTPFHIQAEVTMKTNFFGTRDVCTEL 124 Query: 553 L 555 L Sbjct: 125 L 125
>DHCA_HUMAN (P16152) Carbonyl reductase [NADPH] 1 (EC 1.1.1.184)| (NADPH-dependent carbonyl reductase 1) (Prostaglandin-E(2) 9-reductase) (EC 1.1.1.189) (Prostaglandin 9-ketoreductase) (15-hydroxyprostaglandin dehydrogenase [NADP+]) (EC 1.1.1.197) Length = 276 Score = 40.0 bits (92), Expect = 0.004 Identities = 37/121 (30%), Positives = 53/121 (43%), Gaps = 3/121 (2%) Frame = +1 Query: 202 ALITGGGSGICFEIAAQLAR-HGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGDVRNQ 378 AL+TGG GI I L R V + R AV L++EGL Q D+ + Sbjct: 7 ALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAEGLSPRFHQLDIDDL 66 Query: 379 EDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDT--VGTYTMCYEA 552 + + + +G LD+LVN A F + D TP + + + T GT +C E Sbjct: 67 QSIRALRDFLRKEYGGLDVLVNNAGIAFKVA--DPTPFHIQAEVTMKTNFFGTRDVCTEL 124 Query: 553 L 555 L Sbjct: 125 L 125
>PHAB_PARDE (P50204) Acetoacetyl-CoA reductase (EC 1.1.1.36)| Length = 242 Score = 39.7 bits (91), Expect = 0.006 Identities = 31/117 (26%), Positives = 52/117 (44%) Frame = +1 Query: 196 KAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGDVRN 375 K AL+TGG GI I+ L G VA + D A A G++ ++ V + Sbjct: 3 KVALVTGGSRGIGAAISKALKEAGYTVAANYAGND--DAARAFTEETGIKT--YKWSVAD 58 Query: 376 QEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVGTYTMCY 546 + A + E G + +LVN A A +TP+ ++ V++ + G + M + Sbjct: 59 YDACAAGIKQVEEELGPIAVLVNNAGITRDAMFHKMTPQQWKEVIDTNLTGLFNMTH 115
>FABG_HAEIN (P43713) 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100)| (3-ketoacyl-acyl carrier protein reductase) Length = 242 Score = 39.7 bits (91), Expect = 0.006 Identities = 29/88 (32%), Positives = 42/88 (47%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGD 366 ++GK AL+TG GI IA +L+ GA V + + A L +G G + Sbjct: 1 MQGKIALVTGSTRGIGRAIAEELSSKGAFVIGTATSEKGAEAISAYLGDKG---KGLVLN 57 Query: 367 VRNQEDAARVLASTVEHFGKLDILVNGA 450 V ++E +L FG +DILVN A Sbjct: 58 VTDKESIETLLEQIKNDFGDIDILVNNA 85
>FABG_MYCSM (P71534) 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100)| (3-ketoacyl-acyl carrier protein reductase) Length = 255 Score = 39.7 bits (91), Expect = 0.006 Identities = 32/119 (26%), Positives = 47/119 (39%) Frame = +1 Query: 196 KAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGDVRN 375 ++ L+TGG GI IA +LA G VA+ R D G Q DV + Sbjct: 24 RSVLVTGGNRGIGLAIARRLAADGHKVAVTHRGSGAPDD-----------LFGVQCDVTD 72 Query: 376 QEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVGTYTMCYEA 552 R EH G +++LV A + A +T + F V+ + G + A Sbjct: 73 SAGVDRAFKEVEEHQGPVEVLVANAGISKDAFLMRMTEERFEEVINTNLTGAFRCAQRA 131
>WWOX_DROME (Q9VLU5) WW domain-containing oxidoreductase (EC 1.1.1.-)| Length = 409 Score = 39.7 bits (91), Expect = 0.006 Identities = 31/114 (27%), Positives = 45/114 (39%), Gaps = 4/114 (3%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRA---VGF 357 L G+ ALITG GI +E A LA HG + R R + A+ + E A F Sbjct: 119 LHGRTALITGANCGIGYETARSLAHHGCEIIFACRNRSSAEAAIERIAQERPAARSRCRF 178 Query: 358 QG-DVRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEI 516 D+ + R + + +D L+ A A P T G T ++ Sbjct: 179 AALDLSSLRSVQRFVEEIKQSVSHIDYLILNA--GVFALPYTRTVDGLETTFQV 230
>RDH14_HUMAN (Q9HBH5) Retinol dehydrogenase 14 (EC 1.1.1.-) (Alcohol| dehydrogenase PAN2) Length = 336 Score = 39.7 bits (91), Expect = 0.006 Identities = 35/134 (26%), Positives = 56/134 (41%), Gaps = 15/134 (11%) Frame = +1 Query: 184 VLRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSE--------- 336 ++ GK LITG SG+ AA+L R GA V + R R ++A LR E Sbjct: 40 LMHGKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRRELRQAAECGP 99 Query: 337 --GLRAVG----FQGDVRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGF 498 G+ VG + D+ + ++ +LD+L+N A P T GF Sbjct: 100 EPGVSGVGELIVRELDLASLRSVRAFCQEMLQEEPRLDVLINNA--GIFQCPYMKTEDGF 157 Query: 499 RTVLEIDTVGTYTM 540 ++ +G + + Sbjct: 158 EMQFGVNHLGHFLL 171
>TSC10_EMENI (Q5BE65) 3-ketodihydrosphingosine reductase tsc10 (EC 1.1.1.102)| (3-dehydrosphinganine reductase) (KDS reductase) Length = 357 Score = 39.7 bits (91), Expect = 0.006 Identities = 21/78 (26%), Positives = 39/78 (50%), Gaps = 5/78 (6%) Frame = +1 Query: 196 KAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGL-----RAVGFQ 360 + +ITGG G+ +A QLA+ GA++ I+ R + L++A+ A++ R Sbjct: 37 QTVVITGGSEGMGKAVACQLAQKGANIVIVARTLQKLEEAIEAIKGSAANVNKQRFHYIS 96 Query: 361 GDVRNQEDAARVLASTVE 414 D+ E+ R++ E Sbjct: 97 ADLTKPEECERIMTEVTE 114
>DHRS7_HUMAN (Q9Y394) Dehydrogenase/reductase SDR family member 7 precursor (EC| 1.1.-.-) (Retinal short-chain dehydrogenase/reductase 4) (retSDR4) Length = 339 Score = 39.3 bits (90), Expect = 0.008 Identities = 27/115 (23%), Positives = 54/115 (46%), Gaps = 4/115 (3%) Frame = +1 Query: 208 ITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEG----LRAVGFQGDVRN 375 +TG SGI E+A QL++ G + + RR L++ G + D+ + Sbjct: 55 VTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLDLTD 114 Query: 376 QEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVGTYTM 540 + ++ FG++DILVN + + D + +R ++E++ +GT ++ Sbjct: 115 TGSHEAATKAVLQEFGRIDILVNNGGMSQRSLCMDTSLDVYRKLIELNYLGTVSL 169
>FABI_ANASP (Q05069) Enoyl-[acyl-carrier-protein] reductase [NADH] (EC 1.3.1.9)| (NADH-dependent enoyl-ACP reductase) Length = 258 Score = 38.9 bits (89), Expect = 0.010 Identities = 38/123 (30%), Positives = 58/123 (47%), Gaps = 11/123 (8%) Frame = +1 Query: 187 LRGKAALITG--GGSGICFEIAAQLARHGAHVAI--MGRRREVLDKAVAALRSEGLRAVG 354 L GK AL+TG I + IA QL GA++ I + R +K V+ L ++ Sbjct: 4 LTGKNALVTGIANNRSIAWGIAQQLHAAGANLGITYLPDERGKFEKKVSELVEPLNPSLF 63 Query: 355 FQGDVRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLT-------PKGFRTVLE 513 +V+N E + + +G+LDIL++ A A+ +DLT GF T L+ Sbjct: 64 LPCNVQNDEQIQSTFDTIRDKWGRLDILIHCLA---FANRDDLTGDFSQTSRAGFATALD 120 Query: 514 IDT 522 I T Sbjct: 121 IST 123
>KDUD_ECOLI (P37769) 2-deoxy-D-gluconate 3-dehydrogenase (EC 1.1.1.125)| (2-keto-3-deoxygluconate oxidoreductase) Length = 253 Score = 38.9 bits (89), Expect = 0.010 Identities = 27/88 (30%), Positives = 43/88 (48%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGD 366 L GK A++TG +G+ +A LA+ G I+G + + + + G R + D Sbjct: 8 LEGKVAVVTGCDTGLGQGMALGLAQAGCD--IVGINIVEPTETIEQVTALGRRFLSLTAD 65 Query: 367 VRNQEDAARVLASTVEHFGKLDILVNGA 450 +R + +L V FG +DILVN A Sbjct: 66 LRKIDGIPALLDRAVAEFGHIDILVNNA 93
>HCD2_RAT (O70351) 3-hydroxyacyl-CoA dehydrogenase type-2 (EC 1.1.1.35)| (3-hydroxyacyl-CoA dehydrogenase type II) (Type II HADH) (3-hydroxy-2-methylbutyryl-CoA dehydrogenase) (EC 1.1.1.178) (Endoplasmic reticulum-associated amyloid beta-peptide binding pr Length = 260 Score = 38.9 bits (89), Expect = 0.010 Identities = 29/125 (23%), Positives = 57/125 (45%), Gaps = 7/125 (5%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGD 366 ++G A+ITGG SG+ A +L GA ++ + + G + + Sbjct: 7 VKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPN---SEGETEAKKLGGNCIFAPAN 63 Query: 367 VRNQEDAARVLASTVEHFGKLDILVNGAAGNFLA-------SPEDLTPKGFRTVLEIDTV 525 V ++++ L E FG++D+ VN AG +A + T + F+ V+ ++ + Sbjct: 64 VTSEKEVQAALTLAKEKFGRIDVAVN-CAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLI 122 Query: 526 GTYTM 540 GT+ + Sbjct: 123 GTFNV 127
>DHRS8_PONPY (Q5NVG2) Dehydrogenase/reductase SDR family member 8 precursor (EC| 1.1.1.-) (17-beta-hydroxysteroid dehydrogenase 11) (17-beta-HSD 11) (17-beta-HSD XI) (17betaHSDXI) (17bHSD11) (17betaHSD11) Length = 300 Score = 38.9 bits (89), Expect = 0.010 Identities = 26/94 (27%), Positives = 40/94 (42%) Frame = +1 Query: 169 PFRADVLRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRA 348 P R + G+ LITG G GI A + A+ + + + + L++ A + G + Sbjct: 28 PKRRKSVTGEIVLITGAGHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKCKGLGAKV 87 Query: 349 VGFQGDVRNQEDAARVLASTVEHFGKLDILVNGA 450 F D N+ED G + ILVN A Sbjct: 88 HTFVVDCSNREDIYSAAKKVKAEIGDVSILVNNA 121
>DHRS8_MACFA (Q4JK73) Dehydrogenase/reductase SDR family member 8 precursor (EC| 1.1.1.-) (17-beta-hydroxysteroid dehydrogenase 11) (17-beta-HSD 11) (17-beta-HSD XI) (17betaHSDXI) (17bHSD11) (17betaHSD11) Length = 300 Score = 38.9 bits (89), Expect = 0.010 Identities = 26/94 (27%), Positives = 40/94 (42%) Frame = +1 Query: 169 PFRADVLRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRA 348 P R + G+ LITG G GI A + A+ + + + + L++ A + G + Sbjct: 28 PKRRKSVAGEIVLITGAGHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKCKGLGAKV 87 Query: 349 VGFQGDVRNQEDAARVLASTVEHFGKLDILVNGA 450 F D N+ED G + ILVN A Sbjct: 88 YTFVVDCSNREDIYSSAKKVKAEIGDVSILVNNA 121
>FABG_MYCAV (O07399) 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100)| (3-ketoacyl-acyl carrier protein reductase) Length = 255 Score = 38.9 bits (89), Expect = 0.010 Identities = 32/119 (26%), Positives = 51/119 (42%) Frame = +1 Query: 196 KAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGDVRN 375 ++ L+TGG GI IA +LA VA+ R D GL G + DV + Sbjct: 24 RSVLVTGGNRGIGLAIAQRLAAEAHKVAVTHRGSGAPD---------GL--FGVECDVTD 72 Query: 376 QEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVGTYTMCYEA 552 + R EH G +++LV+ A + A +T + F V+ + G + + A Sbjct: 73 NDAVDRAFTEVEEHQGPVEVLVSNAGISKDAFLIRMTEERFTEVINANLTGAFRVTQRA 131
>DCXR_RAT (Q920P0) L-xylulose reductase (EC 1.1.1.10) (XR)| (Dicarbonyl/L-xylulose reductase) Length = 244 Score = 38.9 bits (89), Expect = 0.010 Identities = 31/89 (34%), Positives = 42/89 (47%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGD 366 L G+ AL+TG G GI L GA V + R RE LD V G+ V D Sbjct: 5 LAGRRALVTGAGKGIGRSTVLALQAAGAQVVAVSRTREDLDSLVR--ECPGVEPVCV--D 60 Query: 367 VRNQEDAARVLASTVEHFGKLDILVNGAA 453 + + E + L++ G +D+LVN AA Sbjct: 61 LADWEATEQALSNV----GPVDLLVNNAA 85
>DCXR_MOUSE (Q91X52) L-xylulose reductase (EC 1.1.1.10) (XR)| (Dicarbonyl/L-xylulose reductase) Length = 244 Score = 38.9 bits (89), Expect = 0.010 Identities = 34/111 (30%), Positives = 50/111 (45%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGD 366 L G+ AL+TG G GI L GA V + R RE LD V G+ V D Sbjct: 5 LAGRRALVTGAGKGIGRSTVLALKAAGAQVVAVSRTREDLDDLVR--ECPGVEPVCV--D 60 Query: 367 VRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEID 519 + + E + L++ G +D+LVN AA L ++T + T ++ Sbjct: 61 LADWEATEQALSNV----GPVDLLVNNAAVALLQPFLEVTKEACDTSFNVN 107
>DHCA_RABIT (P47844) Carbonyl reductase [NADPH] 1 (EC 1.1.1.184)| (NADPH-dependent carbonyl reductase 1) Length = 276 Score = 38.5 bits (88), Expect = 0.013 Identities = 35/123 (28%), Positives = 56/123 (45%), Gaps = 3/123 (2%) Frame = +1 Query: 196 KAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKA-VAALRSEGLRAVGFQGDVR 372 + AL+TG G+ F I L R + ++ + E +A V L++EGL Q D+ Sbjct: 5 RVALVTGANKGVGFAITRALCRLFSGDVLLTAQDEAQGQAAVQQLQAEGLSPRFHQLDIT 64 Query: 373 NQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDT--VGTYTMCY 546 + + + +G L++LVN A F ED TP + + + T GT +C Sbjct: 65 DLQSIRALRDFLRRAYGGLNVLVNNAVIAF--KMEDTTPFHIQAEVTMKTNFDGTRDVCT 122 Query: 547 EAL 555 E L Sbjct: 123 ELL 125
>YDFG_SALTY (P69936) NADP-dependent L-serine/L-allo-threonine dehydrogenase| ydfG (EC 1.1.1.-) Length = 248 Score = 38.5 bits (88), Expect = 0.013 Identities = 29/83 (34%), Positives = 41/83 (49%), Gaps = 1/83 (1%) Frame = +1 Query: 205 LITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSE-GLRAVGFQGDVRNQE 381 L+TG +G IA + +G V GRR E L AL+ E G + Q DVRN+ Sbjct: 4 LVTGATAGFGECIARRFVENGHKVIATGRRHERLQ----ALKDELGENVLTAQLDVRNRA 59 Query: 382 DAARVLASTVEHFGKLDILVNGA 450 ++AS + +D+LVN A Sbjct: 60 AIEEMMASLPAQWRDIDVLVNNA 82
>YDFG_SALTI (P69935) NADP-dependent L-serine/L-allo-threonine dehydrogenase| ydfG (EC 1.1.1.-) Length = 248 Score = 38.5 bits (88), Expect = 0.013 Identities = 29/83 (34%), Positives = 41/83 (49%), Gaps = 1/83 (1%) Frame = +1 Query: 205 LITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSE-GLRAVGFQGDVRNQE 381 L+TG +G IA + +G V GRR E L AL+ E G + Q DVRN+ Sbjct: 4 LVTGATAGFGECIARRFVENGHKVIATGRRHERLQ----ALKDELGENVLTAQLDVRNRA 59 Query: 382 DAARVLASTVEHFGKLDILVNGA 450 ++AS + +D+LVN A Sbjct: 60 AIEEMMASLPAQWRDIDVLVNNA 82
>WWOX_CHICK (Q5F389) WW domain-containing oxidoreductase (EC 1.1.1.-)| Length = 414 Score = 38.1 bits (87), Expect = 0.017 Identities = 39/126 (30%), Positives = 55/126 (43%), Gaps = 10/126 (7%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGD 366 L GK +ITG SGI FE A A HGA+V + R + AV + E +A Sbjct: 122 LSGKVIIITGANSGIGFETAKSFALHGAYVILACRNMSRGNDAVQRILEEWHKA------ 175 Query: 367 VRNQEDAARVLAS--TVEHFGK--------LDILVNGAAGNFLASPEDLTPKGFRTVLEI 516 E LAS +V++F + L ILV AA S LT G + ++ Sbjct: 176 --KVEAMTLDLASLRSVQNFAEAFKSKNMPLHILVCNAA--IFGSSWCLTEDGLESTFQV 231 Query: 517 DTVGTY 534 + +G + Sbjct: 232 NHLGHF 237
>FABG_CHLPN (Q9Z8P2) 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100)| (3-ketoacyl-acyl carrier protein reductase) Length = 248 Score = 38.1 bits (87), Expect = 0.017 Identities = 26/88 (29%), Positives = 37/88 (42%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGD 366 L GK ++TGG GI I +GA V I G E + +L G + D Sbjct: 5 LVGKKVIVTGGSRGIGLGIVKLFLENGADVEIWGLNEERGQAVIESLTGLGGEVSFARVD 64 Query: 367 VRNQEDAARVLASTVEHFGKLDILVNGA 450 V + + ++ K+DILVN A Sbjct: 65 VSHNGGVKDCVQKFLDKHNKIDILVNNA 92
>FABG_ACTAC (P70720) 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100)| (3-ketoacyl-acyl carrier protein reductase) Length = 242 Score = 38.1 bits (87), Expect = 0.017 Identities = 38/116 (32%), Positives = 55/116 (47%), Gaps = 2/116 (1%) Frame = +1 Query: 205 LITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVA-ALRSEGLRAVGFQGDVRNQE 381 LITG GI IA +LA+ G + + R R +AVA A+R G A Q DV + Sbjct: 6 LITGSSRGIGKAIALRLAQAGFDIVVHCRSRIEEAEAVAQAVRELGQNARVLQFDVSCRS 65 Query: 382 DAARVLASTVE-HFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVGTYTMCY 546 +AA L + VE H +++N A P LT + + VL + G Y + + Sbjct: 66 EAADKLTADVEAHGAYYGVVLNAGLTRDNAFPA-LTDEDWDRVLRTNLDGFYNVLH 120
>SORD_KLEPN (P37079) Sorbitol-6-phosphate 2-dehydrogenase (EC 1.1.1.140)| (Glucitol-6-phosphate dehydrogenase) (Ketosephosphate reductase) Length = 267 Score = 38.1 bits (87), Expect = 0.017 Identities = 29/127 (22%), Positives = 53/127 (41%), Gaps = 9/127 (7%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGD 366 L+ ++TGG SGI I +L GAHV +++D G + D Sbjct: 7 LKDNVIIVTGGASGIGLAIVDELLSQGAHV-------QMIDIHGGDRHHNGDNYHFWSTD 59 Query: 367 VRNQEDAARVLASTVEHFGKLDILVNGAAGNF---------LASPEDLTPKGFRTVLEID 519 + + + + + + ++ + ++D LVN A NF A +L F ++ I+ Sbjct: 60 ISSATEVQQTIDAIIQRWSRIDGLVNNAGVNFPRLLVDEKAPAGRYELNEAAFEKMVNIN 119 Query: 520 TVGTYTM 540 G + M Sbjct: 120 QKGVFFM 126
>DHRS8_HUMAN (Q8NBQ5) Dehydrogenase/reductase SDR family member 8 precursor (EC| 1.1.1.-) (17-beta-hydroxysteroid dehydrogenase 11) (17-beta-HSD 11) (17-beta-HSD XI) (17betaHSDXI) (17bHSD11) (17betaHSD11) (Retinal short-chain dehydrogenase/reductase 2) (re Length = 300 Score = 38.1 bits (87), Expect = 0.017 Identities = 26/94 (27%), Positives = 40/94 (42%) Frame = +1 Query: 169 PFRADVLRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRA 348 P R + G+ LITG G GI A + A+ + + + + L++ A + G + Sbjct: 28 PKRRKSVTGEIVLITGAGHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKCKGLGAKV 87 Query: 349 VGFQGDVRNQEDAARVLASTVEHFGKLDILVNGA 450 F D N+ED G + ILVN A Sbjct: 88 HTFVVDCSNREDIYSSAKKVKAEIGDVSILVNNA 121
>DHRS8_MOUSE (Q9EQ06) Dehydrogenase/reductase SDR family member 8 precursor (EC| 1.1.1.-) (17-beta-hydroxysteroid dehydrogenase 11) (17-beta-HSD 11) (17-beta-HSD XI) (17betaHSDXI) (17bHSD11) (17betaHSD11) Length = 298 Score = 37.7 bits (86), Expect = 0.022 Identities = 25/94 (26%), Positives = 40/94 (42%) Frame = +1 Query: 169 PFRADVLRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRA 348 P + + G+ LITG G GI A + A+ + + + +++ A R G +A Sbjct: 28 PKKKKSVAGEIVLITGAGHGIGRLTAYEFAKLNTKLVLWDINKNGIEETAAKCRKLGAQA 87 Query: 349 VGFQGDVRNQEDAARVLASTVEHFGKLDILVNGA 450 F D +E+ E G + ILVN A Sbjct: 88 HPFVVDCSQREEIYSAAKKVKEEVGDVSILVNNA 121
>DCXR_HUMAN (Q7Z4W1) L-xylulose reductase (EC 1.1.1.10) (XR)| (Dicarbonyl/L-xylulose reductase) (Kidney dicarbonyl reductase) (kiDCR) (Carbonyl reductase II) (Sperm surface protein P34H) Length = 244 Score = 37.7 bits (86), Expect = 0.022 Identities = 34/111 (30%), Positives = 48/111 (43%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGD 366 L G+ L+TG G GI L GA V + R + LD V G+ V D Sbjct: 5 LAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVR--ECPGIEPVCV--D 60 Query: 367 VRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEID 519 + + E R L S G +D+LVN AA L ++T + F E++ Sbjct: 61 LGDWEATERALGSV----GPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVN 107
>DCXR_CAVPO (Q920N9) L-xylulose reductase (EC 1.1.1.10) (XR)| (Dicarbonyl/L-xylulose reductase) (Protein P26h) Length = 244 Score = 37.7 bits (86), Expect = 0.022 Identities = 31/89 (34%), Positives = 41/89 (46%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGD 366 L G+ AL+TG G GI L GA V + R RE LD V G+ V D Sbjct: 5 LAGRRALVTGAGKGIGRSTVLALKAAGAQVVAVSRTREDLDDLVR--ECPGVEPVCV--D 60 Query: 367 VRNQEDAARVLASTVEHFGKLDILVNGAA 453 + + E + L++ G D+LVN AA Sbjct: 61 LADWEATEQALSNV----GPADLLVNNAA 85
>NAHB_PSEU8 (P0A170) 1,2-dihydroxy-1,2-dihydronaphthalene dehydrogenase (EC| 1.3.1.60) (Cis-naphthalene dihydrodiol dehydrogenase) Length = 259 Score = 37.4 bits (85), Expect = 0.029 Identities = 26/92 (28%), Positives = 44/92 (47%), Gaps = 1/92 (1%) Frame = +1 Query: 208 ITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGDVRNQEDA 387 ITG GSGI E+ G +V+ + R E + + + L V GDVR+ Sbjct: 9 ITGAGSGIGLELVRSFKSAGYYVSALVRNEEQ-EALLCKEFKDALEIV--VGDVRDHATN 65 Query: 388 ARVLASTVEHFGKLD-ILVNGAAGNFLASPED 480 +++ T++ FG LD + N +++ S E+ Sbjct: 66 EKLIKQTIDRFGHLDCFIANAGIWDYMLSIEE 97
>NAHB_PSEPU (P0A169) 1,2-dihydroxy-1,2-dihydronaphthalene dehydrogenase (EC| 1.3.1.60) (Cis-naphthalene dihydrodiol dehydrogenase) Length = 259 Score = 37.4 bits (85), Expect = 0.029 Identities = 26/92 (28%), Positives = 44/92 (47%), Gaps = 1/92 (1%) Frame = +1 Query: 208 ITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGDVRNQEDA 387 ITG GSGI E+ G +V+ + R E + + + L V GDVR+ Sbjct: 9 ITGAGSGIGLELVRSFKSAGYYVSALVRNEEQ-EALLCKEFKDALEIV--VGDVRDHATN 65 Query: 388 ARVLASTVEHFGKLD-ILVNGAAGNFLASPED 480 +++ T++ FG LD + N +++ S E+ Sbjct: 66 EKLIKQTIDRFGHLDCFIANAGIWDYMLSIEE 97
>DHB8_HUMAN (Q92506) Estradiol 17-beta-dehydrogenase 8 (EC 1.1.1.62)| (17-beta-HSD 8) (17-beta-hydroxysteroid dehydrogenase 8) (Protein Ke6) (Ke-6) Length = 261 Score = 37.4 bits (85), Expect = 0.029 Identities = 29/83 (34%), Positives = 38/83 (45%), Gaps = 7/83 (8%) Frame = +1 Query: 187 LRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRA------ 348 LR AL+TG GSGI ++ +LA GA VA R + V L G + Sbjct: 9 LRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGN 68 Query: 349 -VGFQGDVRNQEDAARVLASTVE 414 FQ DV ++ AAR L V+ Sbjct: 69 HAAFQADV-SEARAARCLLEQVQ 90
>DHB13_RAT (Q5M875) 17-beta hydroxysteroid dehydrogenase 13 precursor (EC| 1.1.-.-) (Short-chain dehydrogenase/reductase 9) Length = 300 Score = 37.4 bits (85), Expect = 0.029 Identities = 26/122 (21%), Positives = 51/122 (41%) Frame = +1 Query: 169 PFRADVLRGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRA 348 P R + G+ LITG G GI A + A+ + + + + +++ A R G Sbjct: 28 PQRRKSVAGQTVLITGAGHGIGRLTAYEFAKQKSRLVLWDISKHGVEETAAKCRKLGAVV 87 Query: 349 VGFQGDVRNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPEDLTPKGFRTVLEIDTVG 528 F D N+ + + + + G ++I+VN A + A + E++ +G Sbjct: 88 HVFVVDCSNRAEIYKSVDQVKKEVGDIEIVVNNAGAIYPADLLSTKDEEITKTFEVNILG 147 Query: 529 TY 534 + Sbjct: 148 HF 149
>Y4EK_RHISN (P55434) Putative short-chain type dehydrogenase/reductase y4eK (EC| 1.-.-.-) Length = 248 Score = 37.4 bits (85), Expect = 0.029 Identities = 37/124 (29%), Positives = 58/124 (46%), Gaps = 2/124 (1%) Frame = +1 Query: 190 RGKAALITGGGSGICFEIAAQLARHGAHVAIMGRRREVLDKAVAALRSEGLRAVGFQGDV 369 R + AL+TG SGI IA +LA G V +GR R LD+ + + G+ V F D+ Sbjct: 6 RYEVALVTGASSGIGKAIALELASAGLRVLALGRDRAALDELHS---TAGIVPVVF--DL 60 Query: 370 RNQEDAARVLASTVEHFGKLDILVNGAAGNFLASPE--DLTPKGFRTVLEIDTVGTYTMC 543 + + +A K+D+LVN AG AS DL+ +++I+ + + Sbjct: 61 SDVSEVYGKIAGE-----KIDVLVNN-AGLLTASASLVDLSEDDIDAMIDINIRSVFKLT 114 Query: 544 YEAL 555 L Sbjct: 115 RHVL 118 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 63,293,847 Number of Sequences: 219361 Number of extensions: 1084660 Number of successful extensions: 4908 Number of sequences better than 10.0: 310 Number of HSP's better than 10.0 without gapping: 4570 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4813 length of database: 80,573,946 effective HSP length: 106 effective length of database: 57,321,680 effective search space used: 4528412720 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
