ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | bart25g03 |
|---|---|
| Clone Library Name | barley_pub |
>CDC2C_ANTMA (Q38774) Cell division control protein 2 homolog C (EC 2.7.11.22)| (EC 2.7.11.23) Length = 305 Score = 205 bits (521), Expect = 8e-53 Identities = 97/150 (64%), Positives = 117/150 (78%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 MEKYEKLEKVGEGTYGKVYKA++K+TGQVVALKKTRLEMD+EG+PPTALRE+ Sbjct: 1 MEKYEKLEKVGEGTYGKVYKALEKSTGQVVALKKTRLEMDEEGVPPTALREVSLLQMLSQ 60 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 +VE KP+LYLVFE+LDTDLKKF+D++R+GP P+PLP ++ Sbjct: 61 SLYVVRLLSVEHVD----CAKNGKPLLYLVFEYLDTDLKKFIDSHRKGPNPRPLPPQQIQ 116 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 SFL+QLCKG++HCH HGVLHRDLKPQNLL+ Sbjct: 117 SFLFQLCKGVSHCHAHGVLHRDLKPQNLLL 146
>CDC2B_ARATH (P25859) Cell division control protein 2 homolog B (EC 2.7.11.22)| (EC 2.7.11.23) Length = 309 Score = 202 bits (515), Expect = 4e-52 Identities = 96/150 (64%), Positives = 112/150 (74%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 MEKYEKLEKVGEGTYGKVYKAM+K TG++VALKKTRLEMD+EGIPPTALREI Sbjct: 1 MEKYEKLEKVGEGTYGKVYKAMEKGTGKLVALKKTRLEMDEEGIPPTALREISLLQMLST 60 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 VE + K LYLVFE+LDTDLKKF+D+YR+GP PKPL +++ Sbjct: 61 SIYVVRLLCVEHVHQPSTKSQSTKSNLYLVFEYLDTDLKKFIDSYRKGPNPKPLEPFLIQ 120 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 ++QLCKG+AHCH HGVLHRDLKPQNLL+ Sbjct: 121 KLMFQLCKGVAHCHSHGVLHRDLKPQNLLL 150
>CDC2D_ANTMA (Q38775) Cell division control protein 2 homolog D (EC 2.7.11.22)| (EC 2.7.11.23) Length = 312 Score = 160 bits (406), Expect = 2e-39 Identities = 83/153 (54%), Positives = 107/153 (69%), Gaps = 1/153 (0%) Frame = +3 Query: 99 SAMEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXX 278 SAM+ + KLEKVGEGTYGKVY+AM+K+TG++VALKKTRL D+EG+PPT LRE+ Sbjct: 9 SAMDAFVKLEKVGEGTYGKVYRAMEKSTGKIVALKKTRLHEDEEGVPPTTLREVSLLRML 68 Query: 279 XXXXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRR-GPAPKPLPTH 455 V+Q K VLYLVFE++DTDLKK++ ++++ G + P+ Sbjct: 69 SRDPHVVRLLDVKQ-----GQNKEGKTVLYLVFEYMDTDLKKYIRSFKQTGESIAPMN-- 121 Query: 456 VVKSFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 VKS +YQLCKG+A CHGHGVLHRDLKP NLL+ Sbjct: 122 -VKSLMYQLCKGVAFCHGHGVLHRDLKPHNLLM 153
>CDC2_MAIZE (P23111) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) Length = 294 Score = 144 bits (363), Expect = 2e-34 Identities = 76/150 (50%), Positives = 97/150 (64%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 ME+YEK+EK+GEGTYG VYKA+DKAT + +ALKK RLE +DEG+P TA+REI Sbjct: 1 MEQYEKVEKIGEGTYGVVYKALDKATNETIALKKIRLEQEDEGVPSTAIREISLLKEMNH 60 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 V + +YLVFE+LD DLKKF+D+ P PT ++K Sbjct: 61 GNIVRLHDVVHSEKR-----------IYLVFEYLDLDLKKFMDSC---PEFAKNPT-LIK 105 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 S+LYQ+ G+A+CH H VLHRDLKPQNLL+ Sbjct: 106 SYLYQILHGVAYCHSHRVLHRDLKPQNLLI 135
>CDC2A_ARATH (P24100) Cell division control protein 2 homolog A (EC 2.7.11.22)| (EC 2.7.11.23) Length = 294 Score = 140 bits (352), Expect = 3e-33 Identities = 74/150 (49%), Positives = 95/150 (63%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 M++YEK+EK+GEGTYG VYKA DK T + +ALKK RLE +DEG+P TA+REI Sbjct: 1 MDQYEKVEKIGEGTYGVVYKARDKVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQH 60 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 V + LYLVFE+LD DLKK +D+ K L H++K Sbjct: 61 SNIVKLQDVVHSEKR-----------LYLVFEYLDLDLKKHMDS--TPDFSKDL--HMIK 105 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 ++LYQ+ +GIA+CH H VLHRDLKPQNLL+ Sbjct: 106 TYLYQILRGIAYCHSHRVLHRDLKPQNLLI 135
>CDC21_ORYSA (P29618) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| Length = 294 Score = 139 bits (351), Expect = 4e-33 Identities = 73/150 (48%), Positives = 95/150 (63%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 ME+YEK EK+GEGTYG VY+A DK T + +ALKK RLE +DEG+P TA+REI Sbjct: 1 MEQYEKEEKIGEGTYGVVYRARDKVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMHH 60 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 + + +YLVFE+LD DLKKF+D+ P PT ++K Sbjct: 61 GNIVRLHDVIHSEKR-----------IYLVFEYLDLDLKKFMDSC---PEFAKNPT-LIK 105 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 S+LYQ+ +G+A+CH H VLHRDLKPQNLL+ Sbjct: 106 SYLYQILRGVAYCHSHRVLHRDLKPQNLLI 135
>CDC28_YEAST (P00546) Cell division control protein 28 (EC 2.7.11.22)| Length = 298 Score = 139 bits (350), Expect = 5e-33 Identities = 76/153 (49%), Positives = 93/153 (60%), Gaps = 3/153 (1%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQ---VVALKKTRLEMDDEGIPPTALREIXXXXX 275 + Y++LEKVGEGTYG VYKA+D GQ VVALKK RLE +DEG+P TA+REI Sbjct: 5 LANYKRLEKVGEGTYGVVYKALDLRPGQGQRVVALKKIRLESEDEGVPSTAIREISLLKE 64 Query: 276 XXXXXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTH 455 V LYLVFEFLD DLK++++ P +PL Sbjct: 65 LKDDNIVRLYDIVHSDAHK----------LYLVFEFLDLDLKRYMEGI---PKDQPLGAD 111 Query: 456 VVKSFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 +VK F+ QLCKGIA+CH H +LHRDLKPQNLL+ Sbjct: 112 IVKKFMMQLCKGIAYCHSHRILHRDLKPQNLLI 144
>CDK2_RAT (Q63699) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 139 bits (349), Expect = 7e-33 Identities = 75/150 (50%), Positives = 94/150 (62%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 ME ++K+EK+GEGTYG VYKA +K TG+VVALKK RL+ + EG+P TA+REI Sbjct: 1 MENFQKVEKIGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 + K LYLVFEFL DLKKF+DA A LP ++K Sbjct: 61 PNIVKLLDVIHTENK-----------LYLVFEFLHQDLKKFMDA----SALTGLPLPLIK 105 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 S+L+QL +G+A CH H VLHRDLKPQNLL+ Sbjct: 106 SYLFQLLQGLAFCHSHRVLHRDLKPQNLLI 135
>CDK2_HUMAN (P24941) Cell division protein kinase 2 (EC 2.7.11.22) (p33 protein| kinase) Length = 298 Score = 139 bits (349), Expect = 7e-33 Identities = 75/150 (50%), Positives = 93/150 (62%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 ME ++K+EK+GEGTYG VYKA +K TG+VVALKK RL+ + EG+P TA+REI Sbjct: 1 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 + K LYLVFEFL DLKKF+DA P PL +K Sbjct: 61 PNIVKLLDVIHTENK-----------LYLVFEFLHQDLKKFMDASALTGIPLPL----IK 105 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 S+L+QL +G+A CH H VLHRDLKPQNLL+ Sbjct: 106 SYLFQLLQGLAFCHSHRVLHRDLKPQNLLI 135
>CDK2_BOVIN (Q5E9Y0) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 139 bits (349), Expect = 7e-33 Identities = 75/150 (50%), Positives = 93/150 (62%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 ME ++K+EK+GEGTYG VYKA +K TG+VVALKK RL+ + EG+P TA+REI Sbjct: 1 MENFQKVEKIGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 + K LYLVFEFL DLKKF+DA P PL +K Sbjct: 61 PNIVKLLDVIHTENK-----------LYLVFEFLHQDLKKFMDASALTGIPLPL----IK 105 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 S+L+QL +G+A CH H VLHRDLKPQNLL+ Sbjct: 106 SYLFQLLQGLAFCHSHRVLHRDLKPQNLLI 135
>CDK2_MOUSE (P97377) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 346 Score = 139 bits (349), Expect = 7e-33 Identities = 75/150 (50%), Positives = 93/150 (62%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 ME ++K+EK+GEGTYG VYKA +K TG+VVALKK RL+ + EG+P TA+REI Sbjct: 1 MENFQKVEKIGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 + K LYLVFEFL DLKKF+DA P PL +K Sbjct: 61 PNIVKLLDVIHTENK-----------LYLVFEFLHQDLKKFMDASALTGIPLPL----IK 105 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 S+L+QL +G+A CH H VLHRDLKPQNLL+ Sbjct: 106 SYLFQLLQGLAFCHSHRVLHRDLKPQNLLI 135
>CDK2_CRIGR (O55076) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 138 bits (348), Expect = 9e-33 Identities = 74/150 (49%), Positives = 94/150 (62%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 ME ++K+EK+GEGTYG VYKA +K TG+VVALKK RL+ + EG+P TA+REI Sbjct: 1 MENFQKVEKIGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 + K LYLVFEFL DLKKF+DA A +P ++K Sbjct: 61 PNIVKLLDVIHTENK-----------LYLVFEFLHQDLKKFMDA----SAVTGIPLPLIK 105 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 S+L+QL +G+A CH H VLHRDLKPQNLL+ Sbjct: 106 SYLFQLLQGLAFCHSHRVLHRDLKPQNLLI 135
>CDC22_XENLA (P24033) Cell division control protein 2 homolog 2 (EC 2.7.11.22)| (EC 2.7.11.23) (p34 protein kinase 2) Length = 302 Score = 138 bits (348), Expect = 9e-33 Identities = 72/150 (48%), Positives = 97/150 (64%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 M++Y K+EK+GEGTYG VYK KATGQVVA+KK RLE ++EG+P TA+REI Sbjct: 1 MDEYTKIEKIGEGTYGVVYKGRHKATGQVVAMKKIRLENEEEGVPSTAIREISLLKELQH 60 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 + Q ++ LYL+FEFL D+KK++D+ P+ + + T +VK Sbjct: 61 PNIVCLLDVLMQDSR-----------LYLIFEFLSMDVKKYLDSI---PSGQYIDTMLVK 106 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 S+LYQ+ +GI CH GVLHRDLKPQNLL+ Sbjct: 107 SYLYQILQGIVFCHSRGVLHRDLKPQNLLI 136
>CDC22_MEDSA (Q05006) Cell division control protein 2 homolog 2 (EC 2.7.11.22)| Length = 294 Score = 138 bits (348), Expect = 9e-33 Identities = 75/151 (49%), Positives = 94/151 (62%), Gaps = 1/151 (0%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 ME+YEK+EK+GEGTYG VYKA D+AT + +ALKK RLE +DEG+P TA+REI Sbjct: 1 MEQYEKVEKIGEGTYGVVYKARDRATNETIALKKIRLEQEDEGVPSTAIREISLLKEMQH 60 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPK-PLPTHVV 461 V + LYLVFE+LD DLKKF+D+ +P+ + Sbjct: 61 RNIVRLQDVVHSEKR-----------LYLVFEYLDLDLKKFMDS-----SPEFAKDQRQI 104 Query: 462 KSFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 K FLYQ+ GIA+CH H VLHRDLKPQNLL+ Sbjct: 105 KMFLYQILCGIAYCHSHRVLHRDLKPQNLLI 135
>CDC2_CHERU (P93101) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) Length = 294 Score = 138 bits (347), Expect = 1e-32 Identities = 73/153 (47%), Positives = 94/153 (61%), Gaps = 3/153 (1%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 M++YEK+EK+GEGTYG VYKA DK T + +ALKK RLE +DEG+P TA+REI Sbjct: 1 MDQYEKVEKIGEGTYGVVYKARDKVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQH 60 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDA---YRRGPAPKPLPTH 455 V + LYLVFE+LD DLKK +D+ + + P Sbjct: 61 GNIVRLQDVVHSEKR-----------LYLVFEYLDLDLKKHMDSCPDFAKDP-------R 102 Query: 456 VVKSFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 ++K FLYQ+ +GIA+CH H VLHRDLKPQNLL+ Sbjct: 103 MIKRFLYQILRGIAYCHSHRVLHRDLKPQNLLI 135
>CDC2A_ANTMA (Q38772) Cell division control protein 2 homolog A (EC 2.7.11.22)| (EC 2.7.11.23) Length = 294 Score = 138 bits (347), Expect = 1e-32 Identities = 74/153 (48%), Positives = 94/153 (61%), Gaps = 3/153 (1%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 ME+YEK+EK+GEGTYG VYKA D+ T + +ALKK RLE +DEG+P TA+REI Sbjct: 1 MEQYEKVEKIGEGTYGVVYKARDRVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQH 60 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDA---YRRGPAPKPLPTH 455 V + LYLVFE+LD DLKK +D+ + + P Sbjct: 61 GNIVRLQDVVHSEKR-----------LYLVFEYLDLDLKKHMDSCPEFSQDP-------R 102 Query: 456 VVKSFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 +VK FLYQ+ +GIA+CH H VLHRDLKPQNLL+ Sbjct: 103 LVKMFLYQILRGIAYCHSHRVLHRDLKPQNLLI 135
>CDC21_XENLA (P35567) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| (EC 2.7.11.23) (p34 protein kinase 1) Length = 302 Score = 136 bits (343), Expect = 3e-32 Identities = 72/150 (48%), Positives = 96/150 (64%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 M++Y K+EK+GEGTYG VYK KATGQVVA+KK RLE ++EG+P TA+REI Sbjct: 1 MDEYTKIEKIGEGTYGVVYKGRHKATGQVVAMKKIRLENEEEGVPSTAIREISLLKELQH 60 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 + Q ++ LYL+FEFL DLKK++D+ P+ + + T +VK Sbjct: 61 PNIVCLLDVLMQDSR-----------LYLIFEFLSMDLKKYLDSI---PSGQYIDTMLVK 106 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 S+LYQ+ +GI CH VLHRDLKPQNLL+ Sbjct: 107 SYLYQILQGIVFCHSRRVLHRDLKPQNLLI 136
>CDK3_HUMAN (Q00526) Cell division protein kinase 3 (EC 2.7.11.22)| Length = 305 Score = 136 bits (343), Expect = 3e-32 Identities = 70/150 (46%), Positives = 95/150 (63%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 M+ ++K+EK+GEGTYG VYKA ++ TGQ+VALKK RL+++ EG+P TA+REI Sbjct: 1 MDMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKH 60 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 V K LYLVFEFL DLKK++D+ LP H++K Sbjct: 61 PNIVRLLDVVHNERK-----------LYLVFEFLSQDLKKYMDS----TPGSELPLHLIK 105 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 S+L+QL +G++ CH H V+HRDLKPQNLL+ Sbjct: 106 SYLFQLLQGVSFCHSHRVIHRDLKPQNLLI 135
>CDC22_ORYSA (P29619) Cell division control protein 2 homolog 2 (EC 2.7.11.22)| Length = 292 Score = 136 bits (343), Expect = 3e-32 Identities = 72/150 (48%), Positives = 93/150 (62%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 ME+YEK+EK+GEGTYG VYK + T + +ALKK RLE +DEG+P TA+REI Sbjct: 1 MEQYEKVEKIGEGTYGVVYKGKHRHTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQH 60 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 V + + +YLVFE+LD DLKK +D+ +P +VK Sbjct: 61 RNIVRLQDVVHK-----------EKCIYLVFEYLDLDLKKHMDS-----SPDFKNHRIVK 104 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 SFLYQ+ +GIA+CH H VLHRDLKPQNLL+ Sbjct: 105 SFLYQILRGIAYCHSHRVLHRDLKPQNLLI 134
>CDK2_MESAU (P48963) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 136 bits (342), Expect = 5e-32 Identities = 73/150 (48%), Positives = 93/150 (62%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 ME ++K+EK+GEGTYG VYKA +K TG+VVALKK RL+ + EG+P TA+REI Sbjct: 1 MENFQKVEKIGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 + K LYLVFE L DLKKF+DA A +P ++K Sbjct: 61 PNIVKLLDVIHTENK-----------LYLVFELLHQDLKKFMDA----SAVTGIPLPLIK 105 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 S+L+QL +G+A CH H VLHRDLKPQNLL+ Sbjct: 106 SYLFQLLQGLAFCHSHRVLHRDLKPQNLLI 135
>CDC2_DICDI (P34112) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) Length = 296 Score = 136 bits (342), Expect = 5e-32 Identities = 76/150 (50%), Positives = 98/150 (65%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 + +Y+KLEK+GEGTYGKVYKA +KATG++VALKK RLE D+G+P TALREI Sbjct: 7 LSRYQKLEKLGEGTYGKVYKAKEKATGRMVALKKIRLE--DDGVPSTALREISLLKEVPH 64 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 + + LYLVFE+LD DLKK++D+ PA P ++K Sbjct: 65 PNVVSLFDVLHCQNR-----------LYLVFEYLDQDLKKYMDSV---PALCP---QLIK 107 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 S+LYQL KG+A+ HGH +LHRDLKPQNLL+ Sbjct: 108 SYLYQLLKGLAYSHGHRILHRDLKPQNLLI 137
>CDC2_RANDY (Q9W739) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) Length = 302 Score = 135 bits (340), Expect = 8e-32 Identities = 71/150 (47%), Positives = 96/150 (64%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 M++Y K+EK+GEGTYG VYK + KATGQ+VA+KK RLE ++EG+P TA+REI Sbjct: 1 MDEYAKIEKIGEGTYGVVYKGVHKATGQIVAMKKIRLENEEEGVPSTAIREISLLKELQH 60 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 + Q ++ LYL+FEFL DLKK++D+ P+ + L +VK Sbjct: 61 PNIVCLLDVLMQDSR-----------LYLIFEFLSMDLKKYLDSI---PSGQYLEAMLVK 106 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 S+LYQ+ +GI CH VLHRDLKPQNLL+ Sbjct: 107 SYLYQILQGIIFCHARRVLHRDLKPQNLLI 136
>CDC2_VIGAC (Q41639) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) Length = 294 Score = 135 bits (339), Expect = 1e-31 Identities = 75/150 (50%), Positives = 91/150 (60%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 ME+YEK+EK+GEGTYG VYKA D+ T + +ALKK RLE +DEG+P TA+REI Sbjct: 1 MEQYEKVEKIGEGTYGVVYKARDRVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQH 60 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 V + LYLVFE+LD DLKK +D+ P P VK Sbjct: 61 RNIVRLQDVVHSEKR-----------LYLVFEYLDLDLKKHMDS---SPEFVKDPRQ-VK 105 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 FLYQ+ GIA+CH H VLHRDLKPQNLL+ Sbjct: 106 MFLYQILCGIAYCHSHRVLHRDLKPQNLLI 135
>CDC2_VIGUN (P52389) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) Length = 294 Score = 134 bits (338), Expect = 1e-31 Identities = 75/150 (50%), Positives = 91/150 (60%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 ME+YEK+EK+GEGTYG VYKA D+ T + +ALKK RLE +DEG+P TA+REI Sbjct: 1 MEQYEKVEKIGEGTYGVVYKARDRVTDETIALKKIRLEQEDEGVPSTAIREISLLKEMQH 60 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 V + LYLVFE+LD DLKK +D+ P P VK Sbjct: 61 RNIVRLQDVVHSEKR-----------LYLVFEYLDLDLKKHMDS---SPEFVKDPRQ-VK 105 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 FLYQ+ GIA+CH H VLHRDLKPQNLL+ Sbjct: 106 MFLYQILCGIAYCHSHRVLHRDLKPQNLLI 135
>CDC2_HUMAN (P06493) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 134 bits (338), Expect = 1e-31 Identities = 71/150 (47%), Positives = 93/150 (62%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 ME Y K+EK+GEGTYG VYK K TGQVVA+KK RLE ++EG+P TA+REI Sbjct: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 + Q ++ LYL+FEFL DLKK++D+ P + + + +VK Sbjct: 61 PNIVSLQDVLMQDSR-----------LYLIFEFLSMDLKKYLDSI---PPGQYMDSSLVK 106 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 S+LYQ+ +GI CH VLHRDLKPQNLL+ Sbjct: 107 SYLYQILQGIVFCHSRRVLHRDLKPQNLLI 136
>CDC2_BOVIN (P48734) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 134 bits (337), Expect = 2e-31 Identities = 71/150 (47%), Positives = 93/150 (62%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 ME Y K+EK+GEGTYG VYK K TGQVVA+KK RLE ++EG+P TA+REI Sbjct: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 + Q ++ LYL+FEFL DLKK++D+ P + + + +VK Sbjct: 61 PNIVSLQDVLMQDSR-----------LYLIFEFLSMDLKKYLDSI---PPGQFMDSSLVK 106 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 S+LYQ+ +GI CH VLHRDLKPQNLL+ Sbjct: 107 SYLYQILQGIVFCHSRRVLHRDLKPQNLLI 136
>CDC2_CARAU (P51958) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 302 Score = 134 bits (336), Expect = 2e-31 Identities = 73/150 (48%), Positives = 93/150 (62%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 M+ Y K+EK+GEGTYG VYK +K TGQVVA+KK RLE ++EG+P TA+REI Sbjct: 1 MDDYLKIEKIGEGTYGVVYKGRNKTTGQVVAMKKIRLESEEEGVPSTAVREISLLKELQH 60 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 + Q +K LYLVFEFL DLKK++D+ G P+ +VK Sbjct: 61 PNVVRLLDVLMQESK-----------LYLVFEFLSMDLKKYLDSIPSGQFMDPM---LVK 106 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 S+LYQ+ +GI CH VLHRDLKPQNLL+ Sbjct: 107 SYLYQILEGILFCHCRRVLHRDLKPQNLLI 136
>CDK2_XENLA (P23437) Cell division protein kinase 2 (EC 2.7.11.22) (CDC2| homolog Eg1 protein kinase) Length = 297 Score = 133 bits (335), Expect = 3e-31 Identities = 71/150 (47%), Positives = 93/150 (62%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 ME ++K+EK+GEGTYG VYKA ++ TG++VALKK RL+ + EG+P TA+REI Sbjct: 1 MENFQKVEKIGEGTYGVVYKARNRETGEIVALKKIRLDTETEGVPSTAIREISLLKELNH 60 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 + K LYLVFEFL+ DLKKF+D G + +VK Sbjct: 61 PNIVKLLDVIHTENK-----------LYLVFEFLNQDLKKFMD----GSNISGISLALVK 105 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 S+L+QL +G+A CH H VLHRDLKPQNLL+ Sbjct: 106 SYLFQLLQGLAFCHSHRVLHRDLKPQNLLI 135
>CDC2_ORYLU (Q9DG98) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 133 bits (334), Expect = 4e-31 Identities = 71/150 (47%), Positives = 93/150 (62%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 ME Y K+EK+GEGTYG VYK K+TGQVVA+KK RLE ++EG+P TA+RE+ Sbjct: 1 MEDYVKIEKIGEGTYGVVYKGRHKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQELKH 60 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 + Q ++ LYL+FEFL DLKK++D+ G P+ +VK Sbjct: 61 PNVVRLLDVLMQESR-----------LYLIFEFLSMDLKKYLDSIPSGQYMDPM---LVK 106 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 S+LYQ+ +GI CH VLHRDLKPQNLL+ Sbjct: 107 SYLYQILEGIYFCHRRRVLHRDLKPQNLLI 136
>CDC2_ORYLA (Q9DGD3) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 133 bits (334), Expect = 4e-31 Identities = 71/150 (47%), Positives = 93/150 (62%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 ME Y K+EK+GEGTYG VYK K+TGQVVA+KK RLE ++EG+P TA+RE+ Sbjct: 1 MEDYVKIEKIGEGTYGVVYKGRHKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQELKH 60 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 + Q ++ LYL+FEFL DLKK++D+ G P+ +VK Sbjct: 61 PNVVRLLDVLMQESR-----------LYLIFEFLSMDLKKYLDSIPSGQYMDPM---LVK 106 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 S+LYQ+ +GI CH VLHRDLKPQNLL+ Sbjct: 107 SYLYQILEGIYFCHRRRVLHRDLKPQNLLI 136
>CDC2_ORYJA (Q9DGA2) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 133 bits (334), Expect = 4e-31 Identities = 71/150 (47%), Positives = 93/150 (62%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 ME Y K+EK+GEGTYG VYK K+TGQVVA+KK RLE ++EG+P TA+RE+ Sbjct: 1 MEDYVKIEKIGEGTYGVVYKGRHKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQELKH 60 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 + Q ++ LYL+FEFL DLKK++D+ G P+ +VK Sbjct: 61 PNVVRLLDVLMQESR-----------LYLIFEFLSMDLKKYLDSIPSGQYMDPM---LVK 106 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 S+LYQ+ +GI CH VLHRDLKPQNLL+ Sbjct: 107 SYLYQILEGIYFCHRRRVLHRDLKPQNLLI 136
>CDC2_ORYCU (Q9DGA5) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 133 bits (334), Expect = 4e-31 Identities = 71/150 (47%), Positives = 93/150 (62%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 ME Y K+EK+GEGTYG VYK K+TGQVVA+KK RLE ++EG+P TA+RE+ Sbjct: 1 MEDYVKIEKIGEGTYGVVYKGRHKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQELKH 60 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 + Q ++ LYL+FEFL DLKK++D+ G P+ +VK Sbjct: 61 PNVVRLLDVLMQESR-----------LYLIFEFLSMDLKKYLDSIPSGQYMDPM---LVK 106 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 S+LYQ+ +GI CH VLHRDLKPQNLL+ Sbjct: 107 SYLYQILEGIYFCHRRRVLHRDLKPQNLLI 136
>CDC2_PONPY (Q5RCH1) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 133 bits (334), Expect = 4e-31 Identities = 70/150 (46%), Positives = 92/150 (61%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 ME Y K+EK+GEGTYG VYK K TGQVV +KK RLE ++EG+P TA+REI Sbjct: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVTMKKIRLESEEEGVPSTAIREISLLKELRH 60 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 + Q ++ LYL+FEFL DLKK++D+ P + + + +VK Sbjct: 61 PNIVSLQDVLMQDSR-----------LYLIFEFLSMDLKKYLDSI---PPGQYMDSSLVK 106 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 S+LYQ+ +GI CH VLHRDLKPQNLL+ Sbjct: 107 SYLYQILQGIVFCHSRRVLHRDLKPQNLLI 136
>CDC2_DROME (P23572) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) Length = 297 Score = 132 bits (333), Expect = 5e-31 Identities = 68/150 (45%), Positives = 92/150 (61%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 ME +EK+EK+GEGTYG VYK ++ TGQ+VA+KK RLE DDEG+P TA+REI Sbjct: 1 MEDFEKIEKIGEGTYGVVYKGRNRLTGQIVAMKKIRLESDDEGVPSTAIREISLLKELKH 60 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 + + + +YL+FEFL DLKK++D+ P K + + +V+ Sbjct: 61 ENIVCLEDVLMEENR-----------IYLIFEFLSMDLKKYMDSL---PVDKHMESELVR 106 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 S+LYQ+ I CH VLHRDLKPQNLL+ Sbjct: 107 SYLYQITSAILFCHRRRVLHRDLKPQNLLI 136
>CDC2_CHICK (P13863) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 132 bits (332), Expect = 7e-31 Identities = 72/150 (48%), Positives = 90/150 (60%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 ME Y K+EK+GEGTYG VYK K TGQVVA+KK RLE ++EG+P TA+REI Sbjct: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELHH 60 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 + Q + LYL+FEFL DLKK++D P+ + L VK Sbjct: 61 PNIVCLQDVLMQDAR-----------LYLIFEFLSMDLKKYLDTI---PSGQYLDRSRVK 106 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 S+LYQ+ +GI CH VLHRDLKPQNLL+ Sbjct: 107 SYLYQILQGIVFCHSRRVLHRDLKPQNLLI 136
>CDK2_CARAU (P43450) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 132 bits (332), Expect = 7e-31 Identities = 72/150 (48%), Positives = 91/150 (60%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 ME ++K+EK+GEGTYG VYKA +K TG+ VALKK RL+ + EG+P TA+REI Sbjct: 1 MESFQKVEKIGEGTYGVVYKAKNKVTGETVALKKIRLDTETEGVPSTAIREISLLKELNH 60 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 + K LYLVFEFL DLK+F+D+ PL VK Sbjct: 61 PNIVKLHDVIHTENK-----------LYLVFEFLHQDLKRFMDSSTVTGISLPL----VK 105 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 S+L+QL +G+A CH H VLHRDLKPQNLL+ Sbjct: 106 SYLFQLLQGLAFCHSHRVLHRDLKPQNLLI 135
>CDC2_RAT (P39951) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 132 bits (331), Expect = 9e-31 Identities = 69/150 (46%), Positives = 93/150 (62%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 ME Y K+EK+GEGTYG VYK + TGQ+VA+KK RLE ++EG+P TA+REI Sbjct: 1 MEDYIKIEKIGEGTYGVVYKGRHRTTGQIVAMKKIRLESEEEGVPSTAIREISLLKELRH 60 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 + Q ++ LYL+FEFL DLKK++D+ P + + + +VK Sbjct: 61 PNIVSLQDVLMQDSR-----------LYLIFEFLSMDLKKYLDSI---PPGQFMDSSLVK 106 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 S+LYQ+ +GI CH VLHRDLKPQNLL+ Sbjct: 107 SYLYQILQGIVFCHSRRVLHRDLKPQNLLI 136
>CDC2H_DICDI (P34117) CDC2-like serine/threonine-protein kinase CRP (EC| 2.7.11.22) (EC 2.7.11.23) Length = 292 Score = 132 bits (331), Expect = 9e-31 Identities = 73/150 (48%), Positives = 92/150 (61%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 MEKY K+EK+GEGTYG V KA ++ TG++VALK+ RL+ +DEG+P TA+REI Sbjct: 1 MEKYSKIEKLGEGTYGIVNKAKNRETGEIVALKRIRLDSEDEGVPCTAIREISLLKELKH 60 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 + K L LVFE+LD DLKK++D G KP +K Sbjct: 61 PNIVRLHDVIHTERK-----------LTLVFEYLDQDLKKYLDEC-GGEISKP----TIK 104 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 SF+YQL KG+A CH H VLHRDLKPQNLL+ Sbjct: 105 SFMYQLLKGVAFCHDHRVLHRDLKPQNLLI 134
>CDK5_XENLA (P51166) Cell division protein kinase 5 (EC 2.7.11.22) (Neuronal| cyclin-dependent kinase 5) Length = 292 Score = 131 bits (330), Expect = 1e-30 Identities = 72/150 (48%), Positives = 91/150 (60%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 M+KYEKLEK+GEGTYG V+KA ++ T ++VALK+ RL+ DDEG+P +ALREI Sbjct: 1 MQKYEKLEKIGEGTYGTVFKAKNRDTHEIVALKRVRLDDDDEGVPSSALREICLLKELKH 60 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 + K L LVFEF D DLKK+ D+ P+ +VK Sbjct: 61 KNIVRLHDVLHSDKK-----------LTLVFEFCDQDLKKYFDSCNGDLDPE-----IVK 104 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 SF+YQL KG+A CH VLHRDLKPQNLL+ Sbjct: 105 SFMYQLLKGLAFCHSRNVLHRDLKPQNLLI 134
>CDK3_MOUSE (Q80YP0) Truncated cell division protein kinase 3 homolog| Length = 186 Score = 130 bits (326), Expect = 3e-30 Identities = 70/150 (46%), Positives = 93/150 (62%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 M+ ++K+EK+GEGTYG VYKA +K TGQ+VALKK RL+++ EG+P TA+REI Sbjct: 1 MDVFQKVEKIGEGTYGVVYKARNKVTGQLVALKKIRLDLEAEGVPSTAVREISLLKELKH 60 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 V + K LY+VFEFL DLK+ +D+ P P VVK Sbjct: 61 PNIIKLLDVVHREKK-----------LYMVFEFLTQDLKRHMDSSPTSELPLP----VVK 105 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 S+L QL +G++ CH H V+HRDLKPQNLL+ Sbjct: 106 SYLAQLLEGVSFCHSHRVIHRDLKPQNLLL 135
>CDC2_MOUSE (P11440) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 130 bits (326), Expect = 3e-30 Identities = 68/150 (45%), Positives = 93/150 (62%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 ME Y K+EK+GEGTYG VYK + TGQ+VA+KK RLE ++EG+P TA+REI Sbjct: 1 MEDYIKIEKIGEGTYGVVYKGRHRVTGQIVAMKKIRLESEEEGVPSTAIREISLLKELRH 60 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 + Q ++ LYL+FEFL DLKK++D+ P + + + +VK Sbjct: 61 PNIVSLQDVLMQDSR-----------LYLIFEFLSMDLKKYLDSI---PPGQFMDSSLVK 106 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 S+L+Q+ +GI CH VLHRDLKPQNLL+ Sbjct: 107 SYLHQILQGIVFCHSRRVLHRDLKPQNLLI 136
>CDK5_MOUSE (P49615) Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein| kinase II catalytic subunit) (TPKII catalytic subunit) (Serine/threonine-protein kinase PSSALRE) (CRK6) Length = 292 Score = 129 bits (325), Expect = 4e-30 Identities = 71/150 (47%), Positives = 90/150 (60%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 M+KYEKLEK+GEGTYG V+KA ++ T ++VALK+ RL+ DDEG+P +ALREI Sbjct: 1 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH 60 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 + K L LVFEF D DLKK+ D+ P+ +VK Sbjct: 61 KNIVRLHDVLHSDKK-----------LTLVFEFCDQDLKKYFDSCNGDLDPE-----IVK 104 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 SFL+QL KG+ CH VLHRDLKPQNLL+ Sbjct: 105 SFLFQLLKGLGFCHSRNVLHRDLKPQNLLI 134
>CDK5_HUMAN (Q00535) Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein| kinase II catalytic subunit) (TPKII catalytic subunit) (Serine/threonine-protein kinase PSSALRE) Length = 292 Score = 129 bits (325), Expect = 4e-30 Identities = 71/150 (47%), Positives = 90/150 (60%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 M+KYEKLEK+GEGTYG V+KA ++ T ++VALK+ RL+ DDEG+P +ALREI Sbjct: 1 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH 60 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 + K L LVFEF D DLKK+ D+ P+ +VK Sbjct: 61 KNIVRLHDVLHSDKK-----------LTLVFEFCDQDLKKYFDSCNGDLDPE-----IVK 104 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 SFL+QL KG+ CH VLHRDLKPQNLL+ Sbjct: 105 SFLFQLLKGLGFCHSRNVLHRDLKPQNLLI 134
>CDK5_BOVIN (Q02399) Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein| kinase II catalytic subunit) (TPKII catalytic subunit) (Proline-directed protein kinase 33 kDa subunit) (PDPK) Length = 292 Score = 129 bits (325), Expect = 4e-30 Identities = 71/150 (47%), Positives = 90/150 (60%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 M+KYEKLEK+GEGTYG V+KA ++ T ++VALK+ RL+ DDEG+P +ALREI Sbjct: 1 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH 60 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 + K L LVFEF D DLKK+ D+ P+ +VK Sbjct: 61 KNIVRLHDVLHSDKK-----------LTLVFEFCDQDLKKYFDSCNGDLDPE-----IVK 104 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 SFL+QL KG+ CH VLHRDLKPQNLL+ Sbjct: 105 SFLFQLLKGLGFCHSRNVLHRDLKPQNLLI 134
>CDC28_CANAL (P43063) Cell division control protein 28 (EC 2.7.11.22)| Length = 317 Score = 129 bits (324), Expect = 6e-30 Identities = 71/151 (47%), Positives = 92/151 (60%), Gaps = 1/151 (0%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMD-KATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXX 281 + Y++ EKVGEGTYG VYKA+D K +VVALKK RLE +DEG+P TA+REI Sbjct: 4 LSDYQRQEKVGEGTYGVVYKALDTKHNNRVVALKKIRLESEDEGVPSTAIREISLLKEMK 63 Query: 282 XXXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVV 461 + + LYLVFEFLD DLKK++++ +G L +++ Sbjct: 64 DDNIVRLYDIIHSDSHK----------LYLVFEFLDLDLKKYMESIPQGVG---LGANMI 110 Query: 462 KSFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 K F+ QL +GI HCH H VLHRDLKPQNLL+ Sbjct: 111 KRFMNQLIRGIKHCHSHRVLHRDLKPQNLLI 141
>CDK5_RAT (Q03114) Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein| kinase II catalytic subunit) (TPKII catalytic subunit) (Serine/threonine-protein kinase PSSALRE) Length = 292 Score = 127 bits (319), Expect = 2e-29 Identities = 70/150 (46%), Positives = 89/150 (59%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 M+KYEKLEK+GEGTYG V+KA ++ T ++VALK+ RL+ DDEG+P +ALREI Sbjct: 1 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH 60 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 + K L LVFEF D DLKK+ D+ P+ +VK Sbjct: 61 KNIVRLHDVLHSDKK-----------LTLVFEFCDQDLKKYFDSCNGDLDPE-----IVK 104 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 S L+QL KG+ CH VLHRDLKPQNLL+ Sbjct: 105 SLLFQLLKGLGFCHSRNVLHRDLKPQNLLI 134
>CDC21_MEDSA (P24923) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| (EC 2.7.11.23) (Fragment) Length = 291 Score = 126 bits (316), Expect = 5e-29 Identities = 70/147 (47%), Positives = 88/147 (59%), Gaps = 1/147 (0%) Frame = +3 Query: 117 EKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXXXX 296 E +EK+GEGTYG VYKA D+ T + +ALKK RLE +DEG+P TA+REI Sbjct: 2 ENVEKIGEGTYGVVYKARDRVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQHRNIV 61 Query: 297 XXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPL-PTHVVKSFL 473 V + LYLVFE+LD DLKK +D+ +P+ + VK FL Sbjct: 62 RLQDVVHSDKR-----------LYLVFEYLDLDLKKHMDS-----SPEFIKDPRQVKMFL 105 Query: 474 YQLCKGIAHCHGHGVLHRDLKPQNLLV 554 YQ+ GIA+CH H VLHRDLKPQNLL+ Sbjct: 106 YQMLCGIAYCHSHRVLHRDLKPQNLLI 132
>CDC2_SCHPO (P04551) Cell division control protein 2 (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinse) Length = 297 Score = 124 bits (311), Expect = 2e-28 Identities = 67/150 (44%), Positives = 86/150 (57%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 ME Y+K+EK+GEGTYG VYKA K +G++VA+KK RLE + EG+P TA+REI Sbjct: 1 MENYQKVEKIGEGTYGVVYKARHKLSGRIVAMKKIRLEDESEGVPSTAIREISLLKEVND 60 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 + LYLVFEFLD DLKK++D A L +V+ Sbjct: 61 ENN-------RSNCVRLLDILHAESKLYLVFEFLDMDLKKYMDRISETGATS-LDPRLVQ 112 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 F YQL G+ CH ++HRDLKPQNLL+ Sbjct: 113 KFTYQLVNGVNFCHSRRIIHRDLKPQNLLI 142
>CDC2H_THEPA (Q27032) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 298 Score = 124 bits (310), Expect = 2e-28 Identities = 69/150 (46%), Positives = 88/150 (58%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 M +Y K+EK+GEGTYG VYKA + G++ ALKK R+E +DEGIP TA+REI Sbjct: 1 MRRYHKMEKIGEGTYGVVYKAQNNH-GEICALKKIRVEEEDEGIPSTAIREISLLKELHH 59 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 + + L LVFE+LD DLKK +DA G P K Sbjct: 60 PNIVWLRDVIHS-----------EKCLTLVFEYLDQDLKKLLDACDGGLEPT-----TAK 103 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 SFLYQ+ +GI++CH H +LHRDLKPQNLL+ Sbjct: 104 SFLYQILRGISYCHDHRILHRDLKPQNLLI 133
>CDC2H_THEAN (Q26671) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 298 Score = 124 bits (310), Expect = 2e-28 Identities = 69/150 (46%), Positives = 88/150 (58%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 M +Y K+EK+GEGTYG VYKA + G++ ALKK R+E +DEGIP TA+REI Sbjct: 1 MRRYHKMEKIGEGTYGVVYKAQNNH-GEICALKKIRVEEEDEGIPSTAIREISLLKELHH 59 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 + + L LVFE+LD DLKK +DA G P K Sbjct: 60 PNIVWLRDVIHS-----------EKCLTLVFEYLDQDLKKLLDACDGGLEPT-----TAK 103 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 SFLYQ+ +GI++CH H +LHRDLKPQNLL+ Sbjct: 104 SFLYQILRGISYCHDHRILHRDLKPQNLLI 133
>CDC2H_PLACH (Q4Y4B1) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 288 Score = 123 bits (308), Expect = 4e-28 Identities = 74/150 (49%), Positives = 85/150 (56%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 MEKY LEK+GEGTYG VYKA + + G+ ALKK RLE +DEGIP TA+REI Sbjct: 1 MEKYHGLEKIGEGTYGVVYKAQN-SDGESFALKKIRLEKEDEGIPSTAIREISILKELRH 59 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 + K L LVFE LD DLKK +D G L + K Sbjct: 60 SNIVKLYDVIH-----------AKKRLILVFEHLDQDLKKLIDVCDGG-----LESVTAK 103 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 SFL QL GIA+CH H VLHRDLKPQNLL+ Sbjct: 104 SFLLQLLNGIAYCHEHRVLHRDLKPQNLLI 133
>CDC2H_PLABA (Q4Z6R1) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 288 Score = 123 bits (308), Expect = 4e-28 Identities = 74/150 (49%), Positives = 85/150 (56%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 MEKY LEK+GEGTYG VYKA + + G+ ALKK RLE +DEGIP TA+REI Sbjct: 1 MEKYHGLEKIGEGTYGVVYKAQN-SDGESFALKKIRLEKEDEGIPSTAIREISILKELRH 59 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 + K L LVFE LD DLKK +D G L + K Sbjct: 60 SNIVKLYDVIH-----------AKKRLILVFEHLDQDLKKLIDVCDGG-----LESVTAK 103 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 SFL QL GIA+CH H VLHRDLKPQNLL+ Sbjct: 104 SFLLQLLNGIAYCHEHRVLHRDLKPQNLLI 133
>CDC2H_PLAVI (Q9XZD6) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (Pvcrk2) Length = 288 Score = 122 bits (306), Expect = 7e-28 Identities = 74/150 (49%), Positives = 84/150 (56%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 MEKY LEK+GEGTYG VYKA + G+ ALKK RLE +DEGIP TA+REI Sbjct: 1 MEKYHGLEKIGEGTYGVVYKAQNNY-GETFALKKIRLEKEDEGIPSTAIREISILKELKH 59 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 + K L LVFE LD DLKK +D G L + K Sbjct: 60 SNIVKLYDVIH-----------TKKRLILVFEHLDQDLKKLLDVCDGG-----LESVTAK 103 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 SFL QL GIA+CH H VLHRDLKPQNLL+ Sbjct: 104 SFLLQLLSGIAYCHEHRVLHRDLKPQNLLI 133
>CDC2H_PLAKH (O96821) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 288 Score = 122 bits (306), Expect = 7e-28 Identities = 74/150 (49%), Positives = 84/150 (56%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 MEKY LEK+GEGTYG VYKA + G+ ALKK RLE +DEGIP TA+REI Sbjct: 1 MEKYHGLEKIGEGTYGVVYKAQNNY-GETFALKKIRLEKEDEGIPSTAIREISILKELKH 59 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 + K L LVFE LD DLKK +D G L + K Sbjct: 60 SNIVKLYDVIH-----------TKKRLILVFEHLDQDLKKLLDVCDGG-----LESVTAK 103 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 SFL QL GIA+CH H VLHRDLKPQNLL+ Sbjct: 104 SFLLQLLSGIAYCHEHRVLHRDLKPQNLLI 133
>CDC2_AJECA (P54119) Cell division control protein 2 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent protein kinase) Length = 324 Score = 122 bits (306), Expect = 7e-28 Identities = 75/166 (45%), Positives = 91/166 (54%), Gaps = 16/166 (9%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKA-TGQVVALKKTRLEMDDEGIPPTALREIXXXXXXX 281 ME Y+K+EK+GEGTYG VYKA D ++VALKK RLE +DEG+P TA+REI Sbjct: 1 MENYQKIEKIGEGTYGVVYKARDLTHPNRIVALKKIRLEAEDEGVPSTAIREISLLKEMH 60 Query: 282 XXXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDA--YRRGPAPKPLP-- 449 V LYLVFEFLD DLKK+++A G K LP Sbjct: 61 DPNIVRLLNIVHADGHK----------LYLVFEFLDLDLKKYMEALPVSEGGRGKALPDG 110 Query: 450 -----------THVVKSFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 +VK F+ QL +GI +CH H VLHRDLKPQNLL+ Sbjct: 111 STLDMNRLGLGEAMVKKFMAQLVEGIRYCHSHRVLHRDLKPQNLLI 156
>CDK5_DROME (P48609) Cell division protein kinase 5 homolog (EC 2.7.11.22)| Length = 294 Score = 120 bits (300), Expect = 3e-27 Identities = 65/150 (43%), Positives = 87/150 (58%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 M+KY+K+EK+GEGTYG V+K ++ T ++VALK+ RL+ DDEG+P +ALREI Sbjct: 1 MQKYDKMEKIGEGTYGTVFKGRNRDTMEIVALKRVRLDEDDEGVPSSALREICLLKELKH 60 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 + K L LVFE D DLKK+ D+ + V + Sbjct: 61 KNIVRLIDVLHSDKK-----------LTLVFEHCDQDLKKYFDSLN-----GEIDMAVCR 104 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 SF+ QL +G+A CH H VLHRDLKPQNLL+ Sbjct: 105 SFMLQLLRGLAFCHSHNVLHRDLKPQNLLI 134
>CDC2H_PLAFK (Q07785) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (PfPK5) Length = 288 Score = 119 bits (297), Expect = 8e-27 Identities = 72/150 (48%), Positives = 82/150 (54%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 MEKY LEK+GEGTYG VYKA + G+ ALKK RLE +DEGIP T +REI Sbjct: 1 MEKYHGLEKIGEGTYGVVYKAQNNY-GETFALKKIRLEKEDEGIPSTTIREISILKELKH 59 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 + K L LVFE LD DLKK +D G L + K Sbjct: 60 SNIVKLYDVIH-----------TKKRLVLVFEHLDQDLKKLLDVCEGG-----LESVTAK 103 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 SFL QL GIA+CH VLHRDLKPQNLL+ Sbjct: 104 SFLLQLLNGIAYCHDRRVLHRDLKPQNLLI 133
>CDC2H_PLAF7 (P61075) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 288 Score = 119 bits (297), Expect = 8e-27 Identities = 72/150 (48%), Positives = 82/150 (54%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 MEKY LEK+GEGTYG VYKA + G+ ALKK RLE +DEGIP T +REI Sbjct: 1 MEKYHGLEKIGEGTYGVVYKAQNNY-GETFALKKIRLEKEDEGIPSTTIREISILKELKH 59 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 + K L LVFE LD DLKK +D G L + K Sbjct: 60 SNIVKLYDVIH-----------TKKRLVLVFEHLDQDLKKLLDVCEGG-----LESVTAK 103 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 SFL QL GIA+CH VLHRDLKPQNLL+ Sbjct: 104 SFLLQLLNGIAYCHDRRVLHRDLKPQNLLI 133
>CDC2_EMENI (Q00646) Cell division control protein 2 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent protein kinase) Length = 323 Score = 119 bits (297), Expect = 8e-27 Identities = 73/165 (44%), Positives = 90/165 (54%), Gaps = 15/165 (9%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKA-TGQVVALKKTRLEMDDEGIPPTALREIXXXXXXX 281 ME Y+K+EK+GEGTYG VYKA + ++VALKK RLE +DEG+P TA+REI Sbjct: 1 MENYQKIEKIGEGTYGVVYKARELTHPNRIVALKKIRLEAEDEGVPSTAIREISLLKEMN 60 Query: 282 XXXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDA--YRRGPAPKPLP-- 449 V LYLVFEFLD DLKK+++A G + LP Sbjct: 61 DPNIVRLLNIVHADGHK----------LYLVFEFLDLDLKKYMEALPVSEGGRGRALPDG 110 Query: 450 ----------THVVKSFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 +VK F+ QL +GI CH H VLHRDLKPQNLL+ Sbjct: 111 STLSRNLGLGDAMVKKFMAQLIEGIRFCHSHRVLHRDLKPQNLLI 155
>PHO85_KLULA (Q92241) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 304 Score = 117 bits (293), Expect = 2e-26 Identities = 65/151 (43%), Positives = 88/151 (58%) Frame = +3 Query: 102 AMEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXX 281 A ++++LEKVG GTY VYK ++K TG VALK+ +L+ +EG P TA+REI Sbjct: 3 APSQFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLD-SEEGTPSTAIREISLMKELK 61 Query: 282 XXXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVV 461 + K L LVFEF+D DLKKF+D +G + K L +V Sbjct: 62 HDNIVRLFDVIHTENK-----------LTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLV 110 Query: 462 KSFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 K F +QL +G+A CH + +LHRDLKPQNLL+ Sbjct: 111 KYFQWQLLQGVAFCHENRILHRDLKPQNLLI 141
>CDC2H_PLAYO (Q7RM49) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 289 Score = 117 bits (293), Expect = 2e-26 Identities = 73/151 (48%), Positives = 85/151 (56%), Gaps = 1/151 (0%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPT-ALREIXXXXXXX 281 MEKY LEK+GEGTYG VYKA + + G+ ALKK RLE +DEGIP T ++REI Sbjct: 1 MEKYHGLEKIGEGTYGVVYKAQN-SDGESFALKKIRLEKEDEGIPSTVSIREISILKELR 59 Query: 282 XXXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVV 461 + K L LVFE LD DLKK +D G L + Sbjct: 60 HSNIVKLYDVIH-----------AKKRLILVFEHLDQDLKKLIDVCDGG-----LESVTA 103 Query: 462 KSFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 KSFL QL GIA+CH H VLHRDLKPQNLL+ Sbjct: 104 KSFLLQLLNGIAYCHEHRVLHRDLKPQNLLI 134
>PHO85_YEAST (P17157) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 305 Score = 117 bits (292), Expect = 3e-26 Identities = 63/152 (41%), Positives = 90/152 (59%) Frame = +3 Query: 99 SAMEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXX 278 S+ ++++LEK+G GTY VYK ++K TG VALK+ +L+ +EG P TA+REI Sbjct: 2 SSSSQFKQLEKLGNGTYATVYKGLNKTTGVYVALKEVKLD-SEEGTPSTAIREISLMKEL 60 Query: 279 XXXXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHV 458 + K L LVFEF+D DLKK++D+ G P+ L ++ Sbjct: 61 KHENIVRLYDVIHTENK-----------LTLVFEFMDNDLKKYMDSRTVGNTPRGLELNL 109 Query: 459 VKSFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 VK F +QL +G+A CH + +LHRDLKPQNLL+ Sbjct: 110 VKYFQWQLLQGLAFCHENKILHRDLKPQNLLI 141
>CC2H3_TRYBB (P54666) Cell division control protein 2 homolog 3 (EC 2.7.11.22)| Length = 311 Score = 116 bits (291), Expect = 4e-26 Identities = 63/149 (42%), Positives = 90/149 (60%) Frame = +3 Query: 108 EKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXX 287 ++Y +++ +GEGTYG VY+A+D+ATGQ+VALKK RL+ DEGIP TALRE+ Sbjct: 21 DRYNRMDILGEGTYGVVYRAVDRATGQIVALKKVRLDRTDEGIPQTALREVSILQEIHHP 80 Query: 288 XXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKS 467 + K LYL+FE++D DLKK ++ +RG A +K Sbjct: 81 NIVNLLDVICADGK-----------LYLIFEYVDHDLKKALE--KRGGA---FTGTTLKK 124 Query: 468 FLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 +YQL +G++ CH H ++HRDLKP N+LV Sbjct: 125 IIYQLLEGLSFCHRHRIVHRDLKPANILV 153
>PHO85_CANGA (Q6FKD4) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 302 Score = 116 bits (290), Expect = 5e-26 Identities = 62/148 (41%), Positives = 90/148 (60%) Frame = +3 Query: 111 KYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXX 290 ++++LEK+G GTY VYK ++K+TG VALK+ +L+ +EG P TA+REI Sbjct: 5 QFKQLEKLGNGTYATVYKGLNKSTGVYVALKEVKLD-SEEGTPSTAIREISLMKELKHDN 63 Query: 291 XXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKSF 470 + K L LVFE++D DLKK++D+ G AP+ L ++VK F Sbjct: 64 IVRLYDVIHTENK-----------LTLVFEYMDNDLKKYMDSRTVGNAPRGLEMNLVKYF 112 Query: 471 LYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 +QL +G+A CH + +LHRDLKPQNLL+ Sbjct: 113 QWQLLEGLAFCHENKILHRDLKPQNLLI 140
>PEF1_SCHPO (O74456) Serine/threonine-protein kinase pef1 (EC 2.7.11.22)| (Cyclin-dependent kinase pef1) (PHO85 homolog) Length = 288 Score = 115 bits (288), Expect = 8e-26 Identities = 65/147 (44%), Positives = 86/147 (58%) Frame = +3 Query: 114 YEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXXX 293 Y++LEK+GEGTY VYK ++ TG++VALK R++ D EG P TA+REI Sbjct: 3 YQRLEKLGEGTYAHVYKGQNRVTGEIVALKVIRIDAD-EGTPSTAIREISLMKELRHPNI 61 Query: 294 XXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKSFL 473 ++ K L LVFE+++ DLKK++D Y A LP VK+F Sbjct: 62 MSLSDVLQTENK-----------LMLVFEYMEKDLKKYMDTYGNQGA---LPPSQVKNFT 107 Query: 474 YQLCKGIAHCHGHGVLHRDLKPQNLLV 554 QL KGI+ CH + VLHRDLKPQNLL+ Sbjct: 108 QQLLKGISFCHENRVLHRDLKPQNLLI 134
>CDC2_CAEEL (P34556) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) Length = 332 Score = 114 bits (284), Expect = 2e-25 Identities = 60/150 (40%), Positives = 86/150 (57%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 + + KLEK+GEGTYG VYK ++ T +VA+KK RLE +DEG+P TA+REI Sbjct: 19 LNDFTKLEKIGEGTYGVVYKGKNRRTNAMVAMKKIRLESEDEGVPSTAVREISLLKELQH 78 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 + Q + L+L+FEFL DLK+++D + + LP +K Sbjct: 79 PNVVGLEAVIMQENR-----------LFLIFEFLSFDLKRYMDQLGK---DEYLPLETLK 124 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 S+ +Q+ + + CH V+HRDLKPQNLLV Sbjct: 125 SYTFQILQAMCFCHQRRVIHRDLKPQNLLV 154
>PHO85_DEBHA (Q6BRY2) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 330 Score = 113 bits (283), Expect = 3e-25 Identities = 64/148 (43%), Positives = 87/148 (58%) Frame = +3 Query: 111 KYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXX 290 ++++LEK+GEGTY VYK ++ GQ+VALK+ L+ +EG P TA+REI Sbjct: 7 QFQQLEKLGEGTYATVYKGRNRTNGQLVALKEINLD-SEEGTPSTAIREISLMKELDHEN 65 Query: 291 XXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKSF 470 + K L LVFEF+D DLKK+++A+ A L +VKSF Sbjct: 66 IVTLYDVIHTENK-----------LTLVFEFMDKDLKKYMEAHGNQGA---LDLKIVKSF 111 Query: 471 LYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 ++QL KGI CH + VLHRDLKPQNLL+ Sbjct: 112 IFQLLKGIMFCHDNRVLHRDLKPQNLLI 139
>PHO85_CANAL (Q9HGY5) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) (CaPHO85) Length = 326 Score = 112 bits (281), Expect = 5e-25 Identities = 64/148 (43%), Positives = 88/148 (59%) Frame = +3 Query: 111 KYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXX 290 ++++LEK+GEGTY VYK ++ATG +VALK+ L+ +EG P TA+REI Sbjct: 7 QFQQLEKLGEGTYATVYKGRNRATGALVALKEISLD-SEEGTPSTAIREISLMKELDHEN 65 Query: 291 XXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKSF 470 + K L LVFE++D DLKK+++ + + A L VVKSF Sbjct: 66 IVTLYDVIHTENK-----------LTLVFEYMDKDLKKYMEVHGQQSA---LDLKVVKSF 111 Query: 471 LYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 ++QL KGI CH + VLHRDLKPQNLL+ Sbjct: 112 MFQLLKGIMFCHDNRVLHRDLKPQNLLI 139
>PHO85_ASHGO (Q751E8) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 303 Score = 112 bits (280), Expect = 7e-25 Identities = 61/148 (41%), Positives = 86/148 (58%) Frame = +3 Query: 111 KYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXX 290 ++++LE++G GTY VYK ++K TG VALK+ +L+ +EG P TA+REI Sbjct: 8 RFKQLERLGNGTYATVYKGLNKTTGLYVALKEVKLD-SEEGTPSTAIREISLMKELKHEN 66 Query: 291 XXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKSF 470 + K L LVFEF+D DLKKF+D+ P+ L +VK F Sbjct: 67 IVRLYDVIHTENK-----------LTLVFEFMDNDLKKFMDSRLDREMPRGLELSLVKYF 115 Query: 471 LYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 +QL +G+A CH + +LHRDLKPQNLL+ Sbjct: 116 QWQLLQGVAFCHENRILHRDLKPQNLLI 143
>PHO85_YARLI (Q6C7U8) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 294 Score = 112 bits (279), Expect = 9e-25 Identities = 65/148 (43%), Positives = 85/148 (57%) Frame = +3 Query: 111 KYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXX 290 ++++LEK+GEGTY VYK ++ TGQ+VALK+ L+ +EG P TA+REI Sbjct: 6 QFQQLEKLGEGTYATVYKGRNRTTGQLVALKEINLD-SEEGTPSTAIREISLMKELKHEN 64 Query: 291 XXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKSF 470 + K L LVFE++D DLKKF+D A L T VK F Sbjct: 65 IVTLYDVIHTENK-----------LNLVFEYMDKDLKKFMDTNGNKGA---LETKQVKWF 110 Query: 471 LYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 +YQL +GI CH + VLHRDLKPQNLL+ Sbjct: 111 MYQLLRGILFCHDNRVLHRDLKPQNLLI 138
>CDC2C_DROME (P23573) Cell division control protein 2 cognate (EC 2.7.11.22) (EC| 2.7.11.23) Length = 314 Score = 110 bits (276), Expect = 2e-24 Identities = 60/150 (40%), Positives = 86/150 (57%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 ++ +++ EK+GEGTYG VYKA +TGQ VALKK RLE + EG+P TA+REI Sbjct: 5 LDNFQRAEKIGEGTYGIVYKARSNSTGQDVALKKIRLEGETEGVPSTAIREISLLKNLKH 64 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 V LY++FE+L+ DLKK +D + P+ ++K Sbjct: 65 PNVVQLFDVVISGNN-----------LYMIFEYLNMDLKKLMDKKKDVFTPQ-----LIK 108 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 S+++Q+ + CH + +LHRDLKPQNLLV Sbjct: 109 SYMHQILDAVGFCHTNRILHRDLKPQNLLV 138
>PCTK2_RAT (O35831) Serine/threonine-protein kinase PCTAIRE-2 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 2) Length = 523 Score = 110 bits (274), Expect = 3e-24 Identities = 68/150 (45%), Positives = 84/150 (56%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 ME Y KLEK+GEGTY VYK K T +VALK+ RLE +EG P TA+RE+ Sbjct: 189 METYIKLEKLGEGTYATVYKGRSKLTENLVALKEIRLE-HEEGAPCTAIREVSLLKDLKH 247 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 V T K L LVFE+LD DLK+++D + H VK Sbjct: 248 ANIVTLHDIVH-TDKS----------LTLVFEYLDKDLKQYMD-----DCGSIMSMHNVK 291 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 FLYQ+ +G+A+CH VLHRDLKPQNLL+ Sbjct: 292 LFLYQILRGLAYCHRRKVLHRDLKPQNLLI 321
>PCTK2_MOUSE (Q8K0D0) Serine/threonine-protein kinase PCTAIRE-2 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 2) Length = 523 Score = 110 bits (274), Expect = 3e-24 Identities = 68/150 (45%), Positives = 84/150 (56%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 ME Y KLEK+GEGTY VYK K T +VALK+ RLE +EG P TA+RE+ Sbjct: 189 METYIKLEKLGEGTYATVYKGRSKLTENLVALKEIRLE-HEEGAPCTAIREVSLLKDLKH 247 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 V T K L LVFE+LD DLK+++D + H VK Sbjct: 248 ANIVTLHDIVH-TDKS----------LTLVFEYLDKDLKQYMD-----DCGNIMSMHNVK 291 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 FLYQ+ +G+A+CH VLHRDLKPQNLL+ Sbjct: 292 LFLYQILRGLAYCHRRKVLHRDLKPQNLLI 321
>PCTK2_HUMAN (Q00537) Serine/threonine-protein kinase PCTAIRE-2 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 2) Length = 523 Score = 110 bits (274), Expect = 3e-24 Identities = 68/150 (45%), Positives = 84/150 (56%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 ME Y KLEK+GEGTY VYK K T +VALK+ RLE +EG P TA+RE+ Sbjct: 189 METYIKLEKLGEGTYATVYKGRSKLTENLVALKEIRLE-HEEGAPCTAIREVSLLKDLKH 247 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 V T K L LVFE+LD DLK+++D + H VK Sbjct: 248 ANIVTLHDIVH-TDKS----------LTLVFEYLDKDLKQYMD-----DCGNIMSMHNVK 291 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 FLYQ+ +G+A+CH VLHRDLKPQNLL+ Sbjct: 292 LFLYQILRGLAYCHRRKVLHRDLKPQNLLI 321
>CRK1_LEIME (Q06309) Cell division protein kinase 2 homolog CRK1 (EC 2.7.11.23)| Length = 301 Score = 109 bits (272), Expect = 6e-24 Identities = 60/148 (40%), Positives = 81/148 (54%) Frame = +3 Query: 111 KYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXX 290 +YE+ EK+GEGTYG VYKA D +T VALK+ RL+ ++EG+P TA+REI Sbjct: 4 RYERQEKIGEGTYGVVYKARDTSTAATVALKRIRLDSEEEGVPCTAIREISLLKELRHEN 63 Query: 291 XXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKSF 470 + L +VFE+LD DLKK++D L ++ F Sbjct: 64 IVKLLDVCHSEHR-----------LTIVFEYLDLDLKKYLDRENGN-----LDAATIQHF 107 Query: 471 LYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 + L +G+A CH VLHRDLKPQNLL+ Sbjct: 108 MRDLLRGVAFCHQRSVLHRDLKPQNLLI 135
>CDC2B_ANTMA (Q38773) Cell division control protein 2 homolog B (EC 2.7.11.22)| (EC 2.7.11.23) (Fragment) Length = 280 Score = 108 bits (271), Expect = 8e-24 Identities = 62/137 (45%), Positives = 79/137 (57%), Gaps = 1/137 (0%) Frame = +3 Query: 147 YGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXXXXXXXXAVEQTT 326 YG VYKA D T + +ALKK RLE +DEG+P TA+REI V + Sbjct: 2 YGVVYKARDIETNEDIALKKIRLEQEDEGVPSTAIREISLLKEMHHENIVNLKDVVHREK 61 Query: 327 KXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPK-PLPTHVVKSFLYQLCKGIAHC 503 + LYLVFE+LD DLKK +D+ P+ H+VK FL Q+ +G+A+C Sbjct: 62 R-----------LYLVFEYLDLDLKKHMDS-----CPEFSQDLHMVKMFLCQILRGVAYC 105 Query: 504 HGHGVLHRDLKPQNLLV 554 H H VLHRDLKPQNLL+ Sbjct: 106 HSHRVLHRDLKPQNLLI 122
>PCTK1_RAT (Q63686) Serine/threonine-protein kinase PCTAIRE-1 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 1) Length = 496 Score = 107 bits (266), Expect = 3e-23 Identities = 63/150 (42%), Positives = 83/150 (55%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 +E Y KL+K+GEGTY VYK K T +VALK+ RLE +EG P TA+RE+ Sbjct: 162 LETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLE-HEEGAPCTAIREVSLLKDLKH 220 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 + + L LVFE+LD DLK+++D + H VK Sbjct: 221 ANIVTLHDIIH-----------TEKSLTLVFEYLDKDLKQYLD-----DCGNVINMHNVK 264 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 FL+QL +G+A+CH VLHRDLKPQNLL+ Sbjct: 265 LFLFQLLRGLAYCHRQKVLHRDLKPQNLLI 294
>PCTK1_MOUSE (Q04735) Serine/threonine-protein kinase PCTAIRE-1 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 1) (CRK5) Length = 496 Score = 107 bits (266), Expect = 3e-23 Identities = 63/150 (42%), Positives = 83/150 (55%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 +E Y KL+K+GEGTY VYK K T +VALK+ RLE +EG P TA+RE+ Sbjct: 162 LETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLE-HEEGAPCTAIREVSLLKDLKH 220 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 + + L LVFE+LD DLK+++D + H VK Sbjct: 221 ANIVTLHDIIH-----------TEKSLTLVFEYLDKDLKQYLD-----DCGNVINMHNVK 264 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 FL+QL +G+A+CH VLHRDLKPQNLL+ Sbjct: 265 LFLFQLLRGLAYCHRQKVLHRDLKPQNLLI 294
>PCTK1_HUMAN (Q00536) Serine/threonine-protein kinase PCTAIRE-1 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 1) Length = 496 Score = 106 bits (265), Expect = 4e-23 Identities = 63/150 (42%), Positives = 83/150 (55%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 +E Y KL+K+GEGTY VYK K T +VALK+ RLE +EG P TA+RE+ Sbjct: 162 LETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLE-HEEGAPCTAIREVSLLKDLKH 220 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 + + L LVFE+LD DLK+++D + H VK Sbjct: 221 ANIVTLHDIIH-----------TEKSLTLVFEYLDKDLKQYLD-----DCGNIINMHNVK 264 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 FL+QL +G+A+CH VLHRDLKPQNLL+ Sbjct: 265 LFLFQLLRGLAYCHRQKVLHRDLKPQNLLI 294
>CDC21_PEA (P19026) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| (EC 2.7.11.23) (p34) (Fragment) Length = 148 Score = 106 bits (264), Expect = 5e-23 Identities = 62/133 (46%), Positives = 75/133 (56%) Frame = +3 Query: 156 VYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXXXXXXXXAVEQTTKXX 335 VYKA D+ T + +ALKK RLE +DEG+P TA+REI V + Sbjct: 2 VYKARDRVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQHRNIVRLQDVVHSEKR-- 59 Query: 336 XXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKSFLYQLCKGIAHCHGHG 515 LYLVFE+LD DLKK +D+ P P V K FLYQ+ GIA+CH H Sbjct: 60 ---------LYLVFEYLDLDLKKHMDS---SPEFVKDPRQV-KMFLYQMLCGIAYCHSHR 106 Query: 516 VLHRDLKPQNLLV 554 VLHRDLKPQNLL+ Sbjct: 107 VLHRDLKPQNLLI 119
>PCTK3_PONPY (Q5RD01) Serine/threonine-protein kinase PCTAIRE-3 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 3) Length = 472 Score = 104 bits (259), Expect = 2e-22 Identities = 60/150 (40%), Positives = 83/150 (55%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 +E Y KL+K+GEGTY V+K K T +VALK+ RLE +EG P TA+RE+ Sbjct: 139 LETYVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLE-HEEGAPCTAIREVSLLKNLKH 197 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 + L LVFE+LD+DLK+++D + H VK Sbjct: 198 ANIVTLHDLIHTDRS-----------LTLVFEYLDSDLKQYLDH-----CGNLMSMHNVK 241 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 F++QL +G+A+CH +LHRDLKPQNLL+ Sbjct: 242 IFMFQLLRGLAYCHHRKILHRDLKPQNLLI 271
>PCTK3_RAT (O35832) Serine/threonine-protein kinase PCTAIRE-3 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 3) Length = 451 Score = 103 bits (258), Expect = 3e-22 Identities = 60/150 (40%), Positives = 83/150 (55%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 +E Y KL+K+GEGTY V+K K T +VALK+ RLE +EG P TA+RE+ Sbjct: 118 LETYVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLE-HEEGAPCTAIREVSLLKDLKH 176 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 + L LVFE+LD+DLK+++D + H VK Sbjct: 177 ANIVTLHDLIHTDRS-----------LTLVFEYLDSDLKQYLDH-----CGNLMNMHNVK 220 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 F++QL +G+A+CH +LHRDLKPQNLL+ Sbjct: 221 IFMFQLLRGLAYCHRRKILHRDLKPQNLLI 250
>PCTK3_MOUSE (Q04899) Serine/threonine-protein kinase PCTAIRE-3 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 3) Length = 451 Score = 103 bits (258), Expect = 3e-22 Identities = 60/150 (40%), Positives = 83/150 (55%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 +E Y KL+K+GEGTY V+K K T +VALK+ RLE +EG P TA+RE+ Sbjct: 118 LETYVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLE-HEEGAPCTAIREVSLLKDLKH 176 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 + L LVFE+LD+DLK+++D + H VK Sbjct: 177 ANIVTLHDLIHTDRS-----------LTLVFEYLDSDLKQYLDH-----CGNLMNMHNVK 220 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 F++QL +G+A+CH +LHRDLKPQNLL+ Sbjct: 221 IFMFQLLRGLAYCHHRKILHRDLKPQNLLI 250
>CDK2_ENTHI (Q04770) Cell division protein kinase 2 homolog (EC 2.7.11.22)| Length = 291 Score = 103 bits (257), Expect = 3e-22 Identities = 57/150 (38%), Positives = 81/150 (54%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 M +YEK +++GEGTYG V KA D + VALKK + E +D+GIP T++REI Sbjct: 1 MTRYEKKQQLGEGTYGVVCKAWDTVCNRYVALKKIKQEREDDGIPVTSVREIAVLLELK- 59 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 LYLVFEF D DL +F+ + +P + + Sbjct: 60 ----------HPNVVDLYDIYLEDKFLYLVFEFCDEDLYQFMSRSSK------IPINETR 103 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 S +YQ+ +G+A CH H +LHRD+KPQN+L+ Sbjct: 104 SIVYQILQGLAFCHYHQILHRDMKPQNILI 133
>CC2H1_TRYCO (P54664) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| Length = 301 Score = 103 bits (257), Expect = 3e-22 Identities = 58/148 (39%), Positives = 80/148 (54%) Frame = +3 Query: 111 KYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXX 290 +Y++LEK+GEG+YG VY+A D T +VALK+ RLE +EG+P TA+REI Sbjct: 4 RYQRLEKIGEGSYGVVYRARDITTDVIVALKRIRLESVEEGVPCTAIREISILKELRHEN 63 Query: 291 XXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKSF 470 + L LVFE+++ DLKK++D A L ++ F Sbjct: 64 IVRLLDVCHSENR-----------LNLVFEYMEMDLKKYMDR-----ASGNLDPATIQEF 107 Query: 471 LYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 + L KG+ CH VLHRDLKP NLL+ Sbjct: 108 MRSLLKGVRFCHERNVLHRDLKPPNLLI 135
>PCTK3_HUMAN (Q07002) Serine/threonine-protein kinase PCTAIRE-3 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 3) Length = 472 Score = 102 bits (253), Expect = 1e-21 Identities = 59/150 (39%), Positives = 82/150 (54%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 +E Y KL+K+GEGTY V+K K +VALK+ RLE +EG P TA+RE+ Sbjct: 139 LETYVKLDKLGEGTYATVFKGRSKLMENLVALKEIRLE-HEEGAPCTAIREVSLLKNLKH 197 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 + L LVFE+LD+DLK+++D + H VK Sbjct: 198 ANIVTLHDLIHTDRS-----------LTLVFEYLDSDLKQYLDH-----CGNLMSMHNVK 241 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 F++QL +G+A+CH +LHRDLKPQNLL+ Sbjct: 242 IFMFQLLRGLAYCHHRKILHRDLKPQNLLI 271
>CC2H1_TRYBB (P38973) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| Length = 301 Score = 100 bits (249), Expect = 3e-21 Identities = 55/148 (37%), Positives = 79/148 (53%) Frame = +3 Query: 111 KYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXX 290 +YE+L+K+GEG+YG V++A D TG +VA+K+ RLE ++EG+P TA+REI Sbjct: 4 RYERLQKIGEGSYGVVFRARDVTTGTIVAVKRIRLEKEEEGVPCTAIREISILKELRHEN 63 Query: 291 XXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKSF 470 + L LVFE ++ DLKK++D L ++ F Sbjct: 64 IVRLLDVCHSEKR-----------LTLVFECMEMDLKKYMD-----HVGGDLDAGTIQEF 107 Query: 471 LYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 + L G+ CH VLHRDLKP NLL+ Sbjct: 108 MRSLLSGVRFCHERNVLHRDLKPPNLLI 135
>PFTK1_HUMAN (O94921) Serine/threonine-protein kinase PFTAIRE-1 (EC 2.7.11.22)| Length = 469 Score = 99.4 bits (246), Expect = 6e-21 Identities = 59/149 (39%), Positives = 82/149 (55%) Frame = +3 Query: 108 EKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXX 287 + YEKLEK+GEG+Y VYK K G++VALK RL+ ++EG P TA+RE Sbjct: 133 DSYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQ-EEEGTPFTAIREASLLKGLKHA 191 Query: 288 XXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKS 467 + K L LVFE++ TDL +++D + G P VK Sbjct: 192 NIVLLHDIIH-----------TKETLTLVFEYVHTDLCQYMDKHPGGLHPDN-----VKL 235 Query: 468 FLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 FL+QL +G+++ H +LHRDLKPQNLL+ Sbjct: 236 FLFQLLRGLSYIHQRYILHRDLKPQNLLI 264
>CDKL1_HUMAN (Q00532) Cyclin-dependent kinase-like 1 (EC 2.7.11.22)| (Serine/threonine-protein kinase KKIALRE) (Protein kinase p42 KKIALRE) Length = 357 Score = 98.6 bits (244), Expect = 1e-20 Identities = 56/150 (37%), Positives = 80/150 (53%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 MEKYEK+ K+GEG+YG V+K ++ TGQ+VA+KK DD I ALREI Sbjct: 1 MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQLKH 60 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 + K L+LVFE+ D + +D Y+RG +P H+VK Sbjct: 61 PNLVNLLEVFRR-----------KRRLHLVFEYCDHTVLHELDRYQRG-----VPEHLVK 104 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 S +Q + + CH H +HRD+KP+N+L+ Sbjct: 105 SITWQTLQAVNFCHKHNCIHRDVKPENILI 134
>CDKL1_BRARE (Q6AXJ9) Cyclin-dependent kinase-like 1 (EC 2.7.11.22)| Length = 350 Score = 98.2 bits (243), Expect = 1e-20 Identities = 56/150 (37%), Positives = 79/150 (52%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 MEKYEK+ K+GEG+YG V+K +K TGQ+VA+KK DD I ALREI Sbjct: 1 MEKYEKISKIGEGSYGVVFKCRNKDTGQIVAIKKFVESEDDPIIKKIALREIRMLKQLKH 60 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 + K L+LVFE+ D + +D Y RG +P H+VK Sbjct: 61 PNLVNLMEVFRRKRK-----------LHLVFEYCDHTVLNELDRYPRG-----VPEHMVK 104 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 S ++Q + + CH +HRD+KP+N+L+ Sbjct: 105 SIIWQTLQAVNFCHKQNCIHRDVKPENILI 134
>PFTK1_MOUSE (O35495) Serine/threonine-protein kinase PFTAIRE-1 (EC 2.7.11.22)| Length = 469 Score = 97.8 bits (242), Expect = 2e-20 Identities = 58/149 (38%), Positives = 82/149 (55%) Frame = +3 Query: 108 EKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXX 287 + YEKLEK+GEG+Y VYK K G++VALK RL+ ++EG P TA+RE Sbjct: 133 DSYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQ-EEEGTPFTAIREASLLKGLKHA 191 Query: 288 XXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKS 467 + K L LVFE++ TDL ++++ + G P VK Sbjct: 192 NIVLLHDIIH-----------TKETLTLVFEYVHTDLCQYMEQHPGGLHPDN-----VKL 235 Query: 468 FLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 FL+QL +G+++ H +LHRDLKPQNLL+ Sbjct: 236 FLFQLLRGLSYIHQRYILHRDLKPQNLLI 264
>CDK6_MOUSE (Q64261) Cell division protein kinase 6 (EC 2.7.11.22)| (Serine/threonine-protein kinase PLSTIRE) (CRK2) Length = 326 Score = 97.1 bits (240), Expect = 3e-20 Identities = 56/153 (36%), Positives = 85/153 (55%), Gaps = 2/153 (1%) Frame = +3 Query: 102 AMEKYEKLEKVGEGTYGKVYKAMD-KATGQVVALKKTRLEMDDEGIPPTALREIXXXXXX 278 A ++YE + ++GEG YGKV+KA D K G+ VALK+ R++ +EG+P + +RE+ Sbjct: 9 ADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTSEEGMPLSTIREVAVLRHL 68 Query: 279 XXXXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKP-LPTH 455 + T + L LVFE +D DL ++D P+P +PT Sbjct: 69 ETFEHPNVVRLFDVCT---VSRTDRETKLTLVFEHVDQDLTTYLDK-----VPEPGVPTE 120 Query: 456 VVKSFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 +K ++QL +G+ H H V+HRDLKPQN+LV Sbjct: 121 TIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILV 153
>CDK6_HUMAN (Q00534) Cell division protein kinase 6 (EC 2.7.11.22)| (Serine/threonine-protein kinase PLSTIRE) Length = 326 Score = 96.7 bits (239), Expect = 4e-20 Identities = 56/153 (36%), Positives = 85/153 (55%), Gaps = 2/153 (1%) Frame = +3 Query: 102 AMEKYEKLEKVGEGTYGKVYKAMD-KATGQVVALKKTRLEMDDEGIPPTALREIXXXXXX 278 A ++YE + ++GEG YGKV+KA D K G+ VALK+ R++ +EG+P + +RE+ Sbjct: 9 ADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLRHL 68 Query: 279 XXXXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKP-LPTH 455 + T + L LVFE +D DL ++D P+P +PT Sbjct: 69 ETFEHPNVVRLFDVCT---VSRTDRETKLTLVFEHVDQDLTTYLDK-----VPEPGVPTE 120 Query: 456 VVKSFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 +K ++QL +G+ H H V+HRDLKPQN+LV Sbjct: 121 TIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILV 153
>CD2L7_HUMAN (Q9NYV4) Cell division cycle 2-related protein kinase 7 (EC| 2.7.11.22) (CDC2-related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS) Length = 1490 Score = 95.9 bits (237), Expect(2) = 4e-20 Identities = 55/150 (36%), Positives = 81/150 (54%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 ++K++ + +GEGTYG+VYKA DK TG++VALKK RL+ + EG P TA+REI Sbjct: 724 VDKFDIIGIIGEGTYGQVYKARDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLIH 783 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 V + K YLVFE++D DL +++ +K Sbjct: 784 RSVVNMKEIVTD-KQDALDFKKDKGAFYLVFEYMDHDLMGLLES-----GLVHFSEDHIK 837 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 SF+ QL +G+ +CH LHRD+K N+L+ Sbjct: 838 SFMKQLMEGLEYCHKKNFLHRDIKCSNILL 867 Score = 21.2 bits (43), Expect(2) = 4e-20 Identities = 10/32 (31%), Positives = 13/32 (40%) Frame = +2 Query: 5 LPDPPRVCASSLRPPSHRPHRERTTPNSDRRK 100 LP PP + L PP + T P +K Sbjct: 669 LPLPPELPGGDLSPPDSPEPKAITPPQQPYKK 700
>CD2L5_MOUSE (Q69ZA1) Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22)| (CDC2-related protein kinase 5) Length = 1511 Score = 96.3 bits (238), Expect = 5e-20 Identities = 55/150 (36%), Positives = 82/150 (54%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 ++K++ + +GEGTYG+VYKA DK TG++VALKK RL+ + EG P TA+REI Sbjct: 702 VDKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTH 761 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 V + K YLVFE++D DL +++ + +K Sbjct: 762 QSIINMKEIVTD-KEDALDFKKDKGAFYLVFEYMDHDLMGLLES-----GLVHFNENHIK 815 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 SF+ QL +G+ +CH LHRD+K N+L+ Sbjct: 816 SFMRQLMEGLDYCHKKNFLHRDIKCSNILL 845
>CD2L5_HUMAN (Q14004) Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22)| (CDC2-related protein kinase 5) (Cholinesterase-related cell division controller) Length = 1512 Score = 96.3 bits (238), Expect = 5e-20 Identities = 55/150 (36%), Positives = 82/150 (54%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 ++K++ + +GEGTYG+VYKA DK TG++VALKK RL+ + EG P TA+REI Sbjct: 702 VDKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTH 761 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 V + K YLVFE++D DL +++ + +K Sbjct: 762 QSIINMKEIVTD-KEDALDFKKDKGAFYLVFEYMDHDLMGLLES-----GLVHFNENHIK 815 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 SF+ QL +G+ +CH LHRD+K N+L+ Sbjct: 816 SFMRQLMEGLDYCHKKNFLHRDIKCSNILL 845
>CDKL2_MACFA (Q4R7T5) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| Length = 570 Score = 93.6 bits (231), Expect = 3e-19 Identities = 54/150 (36%), Positives = 78/150 (52%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 MEKYE L VGEG+YG V K +K TG++VA+KK DD+ + A+REI Sbjct: 1 MEKYENLGLVGEGSYGMVVKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRH 60 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 ++ K YLVFEF+D + ++ + P L VV+ Sbjct: 61 ENLVNLLEVCKK-----------KKRWYLVFEFVDHTILDDLELF-----PNGLDYQVVQ 104 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 +L+Q+ GI CH H ++HRD+KP+N+LV Sbjct: 105 KYLFQIINGIGFCHSHNIIHRDIKPENILV 134
>CDKL2_PONPY (Q5R754) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| Length = 493 Score = 93.6 bits (231), Expect = 3e-19 Identities = 54/150 (36%), Positives = 78/150 (52%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 MEKYE L VGEG+YG V K +K TG++VA+KK DD+ + A+REI Sbjct: 1 MEKYENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRH 60 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 ++ K YLVFEF+D + ++ + P L VV+ Sbjct: 61 ENLVNLLEVCKK-----------KKRWYLVFEFVDHTILDDLELF-----PNGLDYQVVQ 104 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 +L+Q+ GI CH H ++HRD+KP+N+LV Sbjct: 105 KYLFQIINGIGFCHSHNIIHRDIKPENILV 134
>CDKL2_HUMAN (Q92772) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| (Serine/threonine-protein kinase KKIAMRE) (Protein kinase p56 KKIAMRE) Length = 493 Score = 93.6 bits (231), Expect = 3e-19 Identities = 54/150 (36%), Positives = 78/150 (52%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 MEKYE L VGEG+YG V K +K TG++VA+KK DD+ + A+REI Sbjct: 1 MEKYENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRH 60 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 ++ K YLVFEF+D + ++ + P L VV+ Sbjct: 61 ENLVNLLEVCKK-----------KKRWYLVFEFVDHTILDDLELF-----PNGLDYQVVQ 104 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 +L+Q+ GI CH H ++HRD+KP+N+LV Sbjct: 105 KYLFQIINGIGFCHSHNIIHRDIKPENILV 134
>KC47_ORYSA (P29620) CDC2+/CDC28-related protein kinase R2 (EC 2.7.11.22)| Length = 424 Score = 93.2 bits (230), Expect = 4e-19 Identities = 60/149 (40%), Positives = 78/149 (52%) Frame = +3 Query: 108 EKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXX 287 ++Y K E +GEGTYG V+KA+D TG VA+KK RL EG+ TALREI Sbjct: 17 DRYLKREVLGEGTYGVVFKAVDTKTGNTVAIKKIRLGKYKEGVNFTALREIKLLKELKDS 76 Query: 288 XXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKS 467 A K L+LVFEF++TDL+ + R P T KS Sbjct: 77 NIIELIDAFP-----------YKGNLHLVFEFMETDLEAVI--RDRNIVLSPADT---KS 120 Query: 468 FLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 ++ + KG+A CH VLHRD+KP NLL+ Sbjct: 121 YIQMMLKGLAFCHKKWVLHRDMKPNNLLI 149
>CDKL1_MOUSE (Q8CEQ0) Cyclin-dependent kinase-like 1 (EC 2.7.11.22)| Length = 352 Score = 92.8 bits (229), Expect = 6e-19 Identities = 55/150 (36%), Positives = 80/150 (53%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 MEKYEK+ K+GEG+YG V+K ++ TGQ+VA+K+ DD I ALREI Sbjct: 1 MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKRFLETEDDPVIKKIALREIRMLKQLKH 60 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 + K L+LVFE+ D + +D Y+RG P+PL VK Sbjct: 61 PNLVNLLEVFRR-----------KRRLHLVFEYCDHTVLHELDRYQRG-VPEPL----VK 104 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 + +Q + + CH H +HRD+KP+N+L+ Sbjct: 105 NITWQTLQAVNFCHKHNCIHRDVKPENILI 134
>CDKL2_RAT (Q5XIT0) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| Length = 507 Score = 92.4 bits (228), Expect = 8e-19 Identities = 57/154 (37%), Positives = 78/154 (50%), Gaps = 4/154 (2%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 MEKYE L VGEG+YG V K +K +G++VA+KK DD+ + A+REI Sbjct: 1 MEKYENLGLVGEGSYGMVMKCRNKDSGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRH 60 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLD----TDLKKFVDAYRRGPAPKPLPT 452 ++ K YLVFEF+D DLK F P L Sbjct: 61 ENLVNLLEVCKK-----------KKRWYLVFEFVDHTILDDLKLF---------PNGLDY 100 Query: 453 HVVKSFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 VV+ +L+Q+ GI CH H ++HRD+KP+N+LV Sbjct: 101 QVVQKYLFQIINGIGFCHSHNIIHRDIKPENILV 134
>CDKL2_RABIT (Q9TTK0) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| (Serine/threonine-protein kinase KKIAMRE) Length = 566 Score = 92.4 bits (228), Expect = 8e-19 Identities = 53/150 (35%), Positives = 78/150 (52%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 MEKYE L VGEG+YG V K +K +G++VA+KK DD+ + A+REI Sbjct: 1 MEKYENLGLVGEGSYGMVMKCRNKDSGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRH 60 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 ++ K YLVFEF+D + ++ + P L VV+ Sbjct: 61 ENLVNLLEVCKK-----------KKRWYLVFEFVDHTILDDLELF-----PNGLDDQVVQ 104 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 +L+Q+ GI CH H ++HRD+KP+N+LV Sbjct: 105 KYLFQIINGIGFCHSHNIIHRDIKPENILV 134
>AL2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.11.22)| (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 7 protein) Length = 384 Score = 92.4 bits (228), Expect = 8e-19 Identities = 55/151 (36%), Positives = 78/151 (51%) Frame = +3 Query: 102 AMEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXX 281 A Y LEK+GEG+Y VYK + + GQ+VALK + + EG+P TA+RE Sbjct: 48 AASSYLNLEKLGEGSYATVYKGISRINGQLVALKVISMNAE-EGVPFTAIREASLLKGLK 106 Query: 282 XXXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVV 461 + K L VFE++ TDL +++ + G P H V Sbjct: 107 HANIVLLHDIIH-----------TKETLTFVFEYMHTDLAQYMSQHPGGLHP-----HNV 150 Query: 462 KSFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 + F++QL +G+A+ H VLHRDLKPQNLL+ Sbjct: 151 RLFMFQLLRGLAYIHHQHVLHRDLKPQNLLI 181
>CDKL2_MOUSE (Q9QUK0) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| (Serine/threonine-protein kinase KKIAMRE) Length = 568 Score = 92.4 bits (228), Expect = 8e-19 Identities = 57/154 (37%), Positives = 78/154 (50%), Gaps = 4/154 (2%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 MEKYE L VGEG+YG V K +K +G++VA+KK DD+ + A+REI Sbjct: 1 MEKYENLGLVGEGSYGMVMKCRNKDSGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRH 60 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLD----TDLKKFVDAYRRGPAPKPLPT 452 ++ K YLVFEF+D DLK F P L Sbjct: 61 ENLVNLLEVCKK-----------KKRWYLVFEFVDHTILDDLKLF---------PNGLDY 100 Query: 453 HVVKSFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 VV+ +L+Q+ GI CH H ++HRD+KP+N+LV Sbjct: 101 QVVQKYLFQIINGIGFCHSHNIIHRDIKPENILV 134
>CDKL1_RAT (Q66HE7) Cyclin-dependent kinase-like 1 (EC 2.7.11.22)| Length = 352 Score = 90.5 bits (223), Expect = 3e-18 Identities = 54/150 (36%), Positives = 79/150 (52%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 MEKYEK+ K+GEG+YG V+K ++ TGQ+VA+K+ DD I ALREI Sbjct: 1 MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKRFLETEDDPVIKKIALREIRMLKQLKH 60 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 + K L+LVFE+ + +D Y+RG P+PL VK Sbjct: 61 PNLVSLLEVFRR-----------KRRLHLVFEYCHHTVLHELDRYQRG-VPEPL----VK 104 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 + +Q + + CH H +HRD+KP+N+L+ Sbjct: 105 NITWQTLQAVNFCHKHNCIHRDVKPENILI 134
>CD2L2_HUMAN (Q9UQ88) PITSLRE serine/threonine-protein kinase CDC2L2 (EC| 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 2) (CDK11) Length = 780 Score = 89.7 bits (221), Expect = 5e-18 Identities = 49/151 (32%), Positives = 81/151 (53%) Frame = +3 Query: 102 AMEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXX 281 ++E+++ L ++ EGTYG VY+A DK T ++VALK+ ++E + EG P T+LREI Sbjct: 419 SVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ 478 Query: 282 XXXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVV 461 V + +Y+V +++ DLK ++ + +P V Sbjct: 479 HPNIVTVREIVVGSNMDK---------IYIVMNYVEHDLKSLMETMK-----QPFLPGEV 524 Query: 462 KSFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 K+ + QL +G+ H H + +LHRDLK NLL+ Sbjct: 525 KTLMIQLLRGVKHLHDNWILHRDLKTSNLLL 555
>CCRK_RAT (Q4KM34) Cell cycle-related kinase (EC 2.7.11.22)| Length = 346 Score = 89.7 bits (221), Expect = 5e-18 Identities = 57/150 (38%), Positives = 77/150 (51%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 M++Y L ++GEG +G V+KA TG++VALKK L ++GIP ALREI Sbjct: 1 MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGIPNQALREIKALQEIED 60 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 AV L FEF+ +DL + V A +PL VK Sbjct: 61 SQYVVQLKAV----------FPHGAGFVLAFEFMLSDLAEVV-----RHAQRPLAPAQVK 105 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 S+L L KG+A CH + ++HRDLKP NLL+ Sbjct: 106 SYLQMLLKGVAFCHANNIVHRDLKPANLLI 135
>CCRK_MOUSE (Q9JHU3) Cell cycle-related kinase (EC 2.7.11.22)| (Cyclin-kinase-activating kinase p42) (CDK-activating kinase p42) (CAK-kinase p42) (CDK-related protein kinase PNQLARE) Length = 346 Score = 89.7 bits (221), Expect = 5e-18 Identities = 57/150 (38%), Positives = 77/150 (51%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 M++Y L ++GEG +G V+KA TG++VALKK L ++GIP ALREI Sbjct: 1 MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGIPNQALREIKALQEIED 60 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 AV L FEF+ +DL + V A +PL VK Sbjct: 61 SQYVVQLKAV----------FPHGAGFVLAFEFMLSDLAEVV-----RHAQRPLAPAQVK 105 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 S+L L KG+A CH + ++HRDLKP NLL+ Sbjct: 106 SYLQMLLKGVAFCHANNIVHRDLKPANLLI 135
>CD2L1_HUMAN (P21127) PITSLRE serine/threonine-protein kinase CDC2L1 (EC| 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1) Length = 795 Score = 89.7 bits (221), Expect = 5e-18 Identities = 49/151 (32%), Positives = 81/151 (53%) Frame = +3 Query: 102 AMEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXX 281 ++E+++ L ++ EGTYG VY+A DK T ++VALK+ ++E + EG P T+LREI Sbjct: 434 SVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ 493 Query: 282 XXXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVV 461 V + +Y+V +++ DLK ++ + +P V Sbjct: 494 HPNIVTVREIVVGSNMDK---------IYIVMNYVEHDLKSLMETMK-----QPFLPGEV 539 Query: 462 KSFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 K+ + QL +G+ H H + +LHRDLK NLL+ Sbjct: 540 KTLMIQLLRGVKHLHDNWILHRDLKTSNLLL 570
>CDKL4_MOUSE (Q3TZA2) Cyclin-dependent kinase-like 4 (EC 2.7.11.22)| Length = 342 Score = 89.4 bits (220), Expect = 6e-18 Identities = 53/150 (35%), Positives = 77/150 (51%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 MEKYEKL K+GEG+YG V+K +K++GQVVA+KK DD + ALREI Sbjct: 1 MEKYEKLAKIGEGSYGVVFKCRNKSSGQVVAIKKFVESEDDRVVRKIALREIRMLKQLKH 60 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 + K ++LVFE+ D L ++ P + V+K Sbjct: 61 PNLVNLIEVFRRKRK-----------MHLVFEYCDHTLLNELER-----NPNGVSDGVIK 104 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 S L+Q + + CH H +HRD+KP+N+L+ Sbjct: 105 SVLWQTLQALNFCHKHNCIHRDVKPENILI 134
>CCRK_PONPY (Q5R7I7) Cell cycle-related kinase (EC 2.7.11.22)| Length = 346 Score = 89.4 bits (220), Expect = 6e-18 Identities = 56/150 (37%), Positives = 78/150 (52%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 M++Y L ++GEG +G V+KA TG++VALKK L ++GIP ALREI Sbjct: 1 MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGIPNQALREIKALQEMED 60 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 AV + L FEF+ +DL + V A +PL VK Sbjct: 61 NQYVVQLKAVFPHSAG----------FVLAFEFMLSDLAEVV-----RHAQRPLAQAQVK 105 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 S+L L KG++ CH + ++HRDLKP NLL+ Sbjct: 106 SYLQMLLKGVSFCHANNIVHRDLKPANLLI 135
>CD2L1_MOUSE (P24788) PITSLRE serine/threonine-protein kinase CDC2L1 (EC| 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) Length = 784 Score = 89.0 bits (219), Expect = 8e-18 Identities = 49/151 (32%), Positives = 80/151 (52%) Frame = +3 Query: 102 AMEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXX 281 ++E+++ L ++ EGTYG VY+A DK T ++VALK+ ++E + EG P T+LREI Sbjct: 423 SVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ 482 Query: 282 XXXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVV 461 V + +Y+V +++ DLK ++ + +P V Sbjct: 483 HPNIVTVREIVVGSNMDK---------IYIVMNYVEHDLKSLMETMK-----QPFLPGEV 528 Query: 462 KSFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 K+ + QL G+ H H + +LHRDLK NLL+ Sbjct: 529 KTLMIQLLSGVKHLHDNWILHRDLKTSNLLL 559
>CDKL5_HUMAN (O76039) Cyclin-dependent kinase-like 5 (EC 2.7.11.22)| (Serine/threonine-protein kinase 9) Length = 1030 Score = 88.6 bits (218), Expect = 1e-17 Identities = 51/152 (33%), Positives = 79/152 (51%) Frame = +3 Query: 99 SAMEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXX 278 + M K+E L VGEG YG V K K T ++VA+KK + ++E + T LRE+ Sbjct: 8 NVMNKFEILGVVGEGAYGVVLKCRHKETHEIVAIKKFKDSEENEEVKETTLRELKMLRTL 67 Query: 279 XXXXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHV 458 A + K LYLVFE+++ ++ + ++ P +P Sbjct: 68 KQENIVELKEAFRRRGK-----------LYLVFEYVEKNMLELLEEM-----PNGVPPEK 111 Query: 459 VKSFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 VKS++YQL K I CH + ++HRD+KP+NLL+ Sbjct: 112 VKSYIYQLIKAIHWCHKNDIVHRDIKPENLLI 143
>CD2L1_RAT (P46892) PITSLRE serine/threonine-protein kinase CDC2L1 (EC| 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) Length = 436 Score = 88.2 bits (217), Expect = 1e-17 Identities = 48/151 (31%), Positives = 80/151 (52%) Frame = +3 Query: 102 AMEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXX 281 ++E+++ L ++ EGTYG VY+A DK T ++VALK+ ++E + EG P T++REI Sbjct: 75 SVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPLTSIREINTILKAQ 134 Query: 282 XXXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVV 461 V + +Y+V +++ DLK ++ + +P V Sbjct: 135 HPNIVTVREIVVGSNMDK---------IYIVMNYVEHDLKSLMETMK-----QPFLPGEV 180 Query: 462 KSFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 K+ + QL G+ H H + +LHRDLK NLL+ Sbjct: 181 KTLMIQLLSGVKHLHDNWILHRDLKTSNLLL 211
>CDKL4_HUMAN (Q5MAI5) Cyclin-dependent kinase-like 4 (EC 2.7.11.22)| Length = 315 Score = 87.4 bits (215), Expect = 2e-17 Identities = 54/150 (36%), Positives = 75/150 (50%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 MEKYEKL K GEG+YG V+K +K +GQVVA+KK DD + ALREI Sbjct: 1 MEKYEKLAKTGEGSYGVVFKCRNKTSGQVVAVKKFVESEDDPVVKKIALREIRMLKQLKH 60 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 + K ++LVFE+ D L ++ G A V+K Sbjct: 61 PNLVNLIEVFRRKRK-----------MHLVFEYCDHTLLNELERNPNGVA-----DGVIK 104 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 S L+Q + + CH H +HRD+KP+N+L+ Sbjct: 105 SVLWQTLQALNFCHIHNCIHRDIKPENILI 134
>CCRK_MACMU (Q5EDC3) Cell cycle-related kinase (EC 2.7.11.22)| (Cyclin-kinase-activating kinase p42) (CDK-activating kinase p42) (CAK-kinase p42) Length = 243 Score = 87.4 bits (215), Expect = 2e-17 Identities = 56/150 (37%), Positives = 76/150 (50%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 M++Y L ++GEG +G V+KA TG++VALKK L ++G P ALREI Sbjct: 1 MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMGD 60 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 AV L FEF+ +DL + V A +PL VK Sbjct: 61 NQYVVQLKAVFPHGGG----------FVLAFEFMLSDLAEVVRH-----AQRPLAQAQVK 105 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 S+L L KG+A CH + ++HRDLKP NLL+ Sbjct: 106 SYLQMLLKGVAFCHANNIVHRDLKPANLLI 135
>CCRK_HUMAN (Q8IZL9) Cell cycle-related kinase (EC 2.7.11.22)| (Cyclin-kinase-activating kinase p42) (CDK-activating kinase p42) (CAK-kinase p42) Length = 346 Score = 87.4 bits (215), Expect = 2e-17 Identities = 56/150 (37%), Positives = 76/150 (50%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 M++Y L ++GEG +G V+KA TG++VALKK L ++G P ALREI Sbjct: 1 MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMED 60 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 AV L FEF+ +DL + V A +PL VK Sbjct: 61 NQYVVQLKAVFPHGGG----------FVLAFEFMLSDLAEVVRH-----AQRPLAQAQVK 105 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 S+L L KG+A CH + ++HRDLKP NLL+ Sbjct: 106 SYLQMLLKGVAFCHANNIVHRDLKPANLLI 135
>CD2L7_CAEEL (P46551) Putative cell division cycle 2-related protein kinase 7| (EC 2.7.11.22) Length = 730 Score = 86.7 bits (213), Expect = 4e-17 Identities = 54/147 (36%), Positives = 76/147 (51%) Frame = +3 Query: 114 YEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXXX 293 Y L+++GEGTYG+VYKA++ TG+ VALK+ RLE + EG P TA+REI Sbjct: 311 YTMLDQIGEGTYGQVYKAVNNLTGEQVALKRVRLENEKEGFPITAIREIKILRQLHHKNI 370 Query: 294 XXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKSFL 473 V + YLVFE++D DL +++ K + S Sbjct: 371 VRLMDIVIDDI-SMDELKRTRANFYLVFEYVDHDLIGLLESKELVDFNK----DQICSLF 425 Query: 474 YQLCKGIAHCHGHGVLHRDLKPQNLLV 554 QL +G+A+ H G LHRD+K N+LV Sbjct: 426 KQLLEGLAYIHNTGFLHRDIKCSNILV 452
>BUR1_EMENI (Q96VK3) Serine/threonine-protein kinase bur1 (EC 2.7.11.22) (EC| 2.7.11.23) (Pitalre-like kinase A) Length = 544 Score = 86.3 bits (212), Expect = 5e-17 Identities = 49/152 (32%), Positives = 79/152 (51%) Frame = +3 Query: 99 SAMEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXX 278 +++ ++E L K+GEGT+G+VYKA K G +VALKK + + +G P TALREI Sbjct: 20 TSIREFEFLGKLGEGTFGEVYKARAKRDGSIVALKKILMHNERDGFPITALREIKLLKML 79 Query: 279 XXXXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHV 458 E + KP +Y+VF +++ DL ++ Sbjct: 80 SHTNIMQLR---EMAVERSKGEGRKKPSMYMVFPYMEHDLSGLLE-----NPEVHFSEAQ 131 Query: 459 VKSFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 +K ++ QL +G+ + HG+ +LHRD+K NLL+ Sbjct: 132 IKCYMIQLLEGLKYLHGNCILHRDMKAANLLI 163
>BUR1_ASPFU (Q4WTN5) Serine/threonine-protein kinase bur1 (EC 2.7.11.22) (EC| 2.7.11.23) Length = 580 Score = 85.9 bits (211), Expect = 7e-17 Identities = 50/152 (32%), Positives = 79/152 (51%) Frame = +3 Query: 99 SAMEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXX 278 +++ +E L K+GEGT+G+VYKA K G +VALKK + + +G P TALREI Sbjct: 20 TSIRDFEFLGKLGEGTFGEVYKARSKKDGSIVALKKILMHNEKDGFPITALREIKLLKML 79 Query: 279 XXXXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHV 458 E + KP +Y+V +++ DL ++ PA Sbjct: 80 SHRNILQLK---EMAVERSKGDGRKKPSMYMVTPYMEHDLSGLLE----NPAVN-FTEPQ 131 Query: 459 VKSFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 +K ++ QL +G+ + HG+ +LHRD+K NLL+ Sbjct: 132 IKCYMLQLLEGLKYLHGNRILHRDMKAANLLI 163
>YP62_CAEEL (Q09437) Putative serine/threonine-protein kinase B0495.2 (EC| 2.7.11.1) Length = 719 Score = 85.1 bits (209), Expect = 1e-16 Identities = 51/150 (34%), Positives = 74/150 (49%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 +++YE + +V EGT+G VY+ DK T ++VALK+ ++E + EG P TALREI Sbjct: 353 IDEYECVNRVDEGTFGVVYRGKDKRTDEIVALKRLKMEKEKEGFPITALREINMLLKAGN 412 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 + +Y+ EF++ D+K +D R K K Sbjct: 413 HPNIVNVKEI--------LLGSNMDKIYMAMEFVEHDMKSLLDTMSR--RNKRFSIGEQK 462 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 + L QL GI H H +LHRDLK NLL+ Sbjct: 463 TLLQQLLSGIEHMHKLWILHRDLKTSNLLM 492
>BUR1_NEUCR (Q871M9) Serine/threonine-protein kinase bur-1 (EC 2.7.11.22) (EC| 2.7.11.23) Length = 545 Score = 84.7 bits (208), Expect = 2e-16 Identities = 52/153 (33%), Positives = 82/153 (53%), Gaps = 1/153 (0%) Frame = +3 Query: 99 SAMEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREI-XXXXX 275 S + YE L K+GEGT+G+V++A + TG +VALKK + + +G P TALREI Sbjct: 21 SRIADYEVLGKLGEGTFGEVHRARSRKTGALVALKKIIMHNERDGFPITALREIKLLKLL 80 Query: 276 XXXXXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTH 455 A+E + +P++Y+V ++D DL +D P+ + Sbjct: 81 SHKNVLRLEEMAIEHPPR---TDKRTRPIVYMVTPYMDHDLSGLLD----NPSVR-FTEP 132 Query: 456 VVKSFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 VK +L QL +G+ + H + +LHRD+K NLL+ Sbjct: 133 QVKCYLLQLLEGLKYLHANHILHRDMKAANLLI 165
>CC2H2_TRYBB (P54665) Cell division control protein 2 homolog 2 (EC 2.7.11.22)| Length = 345 Score = 84.7 bits (208), Expect = 2e-16 Identities = 53/175 (30%), Positives = 82/175 (46%) Frame = +3 Query: 30 PPPSAPHXXXXXXXXXXXXXXXXSAMEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKT 209 P PSA S ++Y ++EKVGEG+YG VYK D TG+ VA+K+ Sbjct: 18 PLPSAGPASFVPRSLRPAPLRGTSTPDRYSRIEKVGEGSYGIVYKCHDNFTGRTVAMKRI 77 Query: 210 RLEMDDEGIPPTALREIXXXXXXXXXXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLD 389 L ++D G+P TA+RE+ V K L L+FE+++ Sbjct: 78 PLIVNDGGVPSTAVREVSLLRELNHPYVVRLLDVVLHEAK-----------LLLIFEYME 126 Query: 390 TDLKKFVDAYRRGPAPKPLPTHVVKSFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 DL+ + +R A ++ ++QL G+ CH +HRD+KP N+L+ Sbjct: 127 QDLQGMLK--QRNTA---FVGGKLRRIMFQLLLGLHECHSRRFVHRDIKPSNILI 176
>CDC2H_CRIFA (Q01917) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 474 Score = 84.0 bits (206), Expect = 3e-16 Identities = 51/154 (33%), Positives = 77/154 (50%), Gaps = 2/154 (1%) Frame = +3 Query: 99 SAMEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXX 278 S + +Y + K+GEGTYG VYK + TG+VVA K+ + DDEGIP A+REI Sbjct: 2 STLGRYRHVVKLGEGTYGMVYKGTEIQTGRVVAFKRMVVTSDDEGIPGAAIREICLLKEL 61 Query: 279 XXXXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPL--PT 452 P + ++FE D DLK+++++ P+ L Sbjct: 62 R-----------HNNVVELFEVLFDPPKITMIFELCDCDLKRYMES-----RPQRLLDAN 105 Query: 453 HVVKSFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 ++ L Q+ G+ + HG V+HRD+KPQN+ V Sbjct: 106 TEMRPILKQIFLGLEYLHGRCVVHRDMKPQNIFV 139
>KP58_DROME (Q9VPC0) Serine/threonine-protein kinase PITSLRE (EC 2.7.11.22)| (Cell division cycle 2-like) Length = 952 Score = 83.6 bits (205), Expect = 4e-16 Identities = 47/151 (31%), Positives = 79/151 (52%) Frame = +3 Query: 102 AMEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXX 281 ++E+++ L ++ EGTYG VY+A DK T ++VALK+ ++E + EG P T+LREI Sbjct: 554 SVEEFQCLNRIEEGTYGVVYRAKDKRTNEIVALKRLKMEKEKEGFPITSLREINTLLKGQ 613 Query: 282 XXXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVV 461 V + +++V ++++ DLK ++ + + V Sbjct: 614 HPNIVTVREIVVGSNMDK---------IFIVMDYVEHDLKSLMETMKN--RKQSFFPGEV 662 Query: 462 KSFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 K QL + +AH H + +LHRDLK NLL+ Sbjct: 663 KCLTQQLLRAVAHLHDNWILHRDLKTSNLLL 693
>CDK9_CHICK (Q5ZKN1) Cell division protein kinase 9 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9) Length = 372 Score = 83.6 bits (205), Expect = 4e-16 Identities = 53/156 (33%), Positives = 77/156 (49%), Gaps = 6/156 (3%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 + KYEKL K+G+GT+G+V+KA + TG+ VALKK +E + EG P TALREI Sbjct: 16 VSKYEKLAKIGQGTFGEVFKAKHRQTGKKVALKKVLMENEKEGFPITALREI---KILQL 72 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHV-- 458 +E K +YLVF+F + DL + THV Sbjct: 73 LKHENVVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLS-----------NTHVKF 121 Query: 459 ----VKSFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 +K + L G+ + H + +LHRD+K N+L+ Sbjct: 122 TLSEIKKVMQMLLNGLYYIHRNKILHRDMKAANVLI 157
>CDK7_MOUSE (Q03147) Cell division protein kinase 7 (EC 2.7.11.22) (EC| 2.7.11.23) (CDK-activating kinase) (CAK) (TFIIH basal transcription factor complex kinase subunit) (39 kDa protein kinase) (P39 Mo15) (Protein-tyrosine kinase MPK-7) (CR4 protein kinas Length = 346 Score = 83.2 bits (204), Expect = 5e-16 Identities = 55/155 (35%), Positives = 81/155 (52%), Gaps = 3/155 (1%) Frame = +3 Query: 99 SAMEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDE---GIPPTALREIXXX 269 S ++YEKL+ +GEG + VYKA DK T Q+VA+KK +L E GI TALREI Sbjct: 7 SRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLL 66 Query: 270 XXXXXXXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLP 449 A K + LVF+F++TDL+ + + + P Sbjct: 67 QELSHPNIIGLLDA-----------FGHKSNISLVFDFMETDLEVII----KDNSLVLTP 111 Query: 450 THVVKSFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 +H +K+++ +G+ + H H +LHRDLKP NLL+ Sbjct: 112 SH-IKAYMLMTLQGLEYLHQHWILHRDLKPNNLLL 145
>CDK7_HUMAN (P50613) Cell division protein kinase 7 (EC 2.7.11.22) (EC| 2.7.11.23) (CDK-activating kinase) (CAK) (TFIIH basal transcription factor complex kinase subunit) (39 kDa protein kinase) (P39 Mo15) (STK1) (CAK1) Length = 346 Score = 83.2 bits (204), Expect = 5e-16 Identities = 55/155 (35%), Positives = 81/155 (52%), Gaps = 3/155 (1%) Frame = +3 Query: 99 SAMEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDE---GIPPTALREIXXX 269 S ++YEKL+ +GEG + VYKA DK T Q+VA+KK +L E GI TALREI Sbjct: 7 SRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLL 66 Query: 270 XXXXXXXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLP 449 A K + LVF+F++TDL+ + + + P Sbjct: 67 QELSHPNIIGLLDA-----------FGHKSNISLVFDFMETDLEVII----KDNSLVLTP 111 Query: 450 THVVKSFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 +H +K+++ +G+ + H H +LHRDLKP NLL+ Sbjct: 112 SH-IKAYMLMTLQGLEYLHQHWILHRDLKPNNLLL 145
>CDK9_HUMAN (P50750) Cell division protein kinase 9 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9) (Serine/threonine-protein kinase PITALRE) (C-2K) (Cell division cycle 2-like protein kinase 4) Length = 372 Score = 82.8 bits (203), Expect = 6e-16 Identities = 51/150 (34%), Positives = 74/150 (49%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 + KYEKL K+G+GT+G+V+KA + TGQ VALKK +E + EG P TALREI Sbjct: 16 VSKYEKLAKIGQGTFGEVFKARHRKTGQKVALKKVLMENEKEGFPITALREI---KILQL 72 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 +E K +YLVF+F + DL + +K Sbjct: 73 LKHENVVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLL-----SNVLVKFTLSEIK 127 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 + L G+ + H + +LHRD+K N+L+ Sbjct: 128 RVMQMLLNGLYYIHRNKILHRDMKAANVLI 157
>BUR1_GIBZE (Q4I5U9) Serine/threonine-protein kinase BUR1 (EC 2.7.11.22) (EC| 2.7.11.23) Length = 473 Score = 82.8 bits (203), Expect = 6e-16 Identities = 51/153 (33%), Positives = 81/153 (52%), Gaps = 1/153 (0%) Frame = +3 Query: 99 SAMEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREI-XXXXX 275 S + YE L K+GEGT+G+V++A + TG +VALKK + + +G P TALREI Sbjct: 32 SRISDYELLGKLGEGTFGEVHRARLRKTGALVALKKIIMHHEKDGFPITALREIKLLKLL 91 Query: 276 XXXXXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTH 455 A+E T+ KP++Y+ ++D DL +D P+ + Sbjct: 92 SHKNILRLEDMAIEHPTR--QTDKRKKPIVYMATPYMDHDLSGLLD----NPSVQ-FKEP 144 Query: 456 VVKSFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 +K ++ QL +G+ + H +LHRD+K NLL+ Sbjct: 145 QIKCYMLQLLEGLRYLHDSRILHRDMKAANLLI 177
>CDK9_RAT (Q641Z4) Cell division protein kinase 9 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9) Length = 372 Score = 82.4 bits (202), Expect = 8e-16 Identities = 51/148 (34%), Positives = 73/148 (49%) Frame = +3 Query: 111 KYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXX 290 KYEKL K+G+GT+G+V+KA + TGQ VALKK +E + EG P TALREI Sbjct: 18 KYEKLAKIGQGTFGEVFKAKHRQTGQKVALKKVLMENEKEGFPITALREI---KILQLLK 74 Query: 291 XXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKSF 470 +E K +YLVF+F + DL + +K Sbjct: 75 HENVVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLL-----SNVLVKFTLSEIKRV 129 Query: 471 LYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 + L G+ + H + +LHRD+K N+L+ Sbjct: 130 MQMLLNGLYYIHRNKILHRDMKAANVLI 157
>CDK9_MOUSE (Q99J95) Cell division protein kinase 9 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9) Length = 372 Score = 82.4 bits (202), Expect = 8e-16 Identities = 51/148 (34%), Positives = 73/148 (49%) Frame = +3 Query: 111 KYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXX 290 KYEKL K+G+GT+G+V+KA + TGQ VALKK +E + EG P TALREI Sbjct: 18 KYEKLAKIGQGTFGEVFKAKHRQTGQKVALKKVLMENEKEGFPITALREI---KILQLLK 74 Query: 291 XXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKSF 470 +E K +YLVF+F + DL + +K Sbjct: 75 HENVVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLL-----SNVLVKFTLSEIKRV 129 Query: 471 LYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 + L G+ + H + +LHRD+K N+L+ Sbjct: 130 MQMLLNGLYYIHRNKILHRDMKAANVLI 157
>CDK9_BOVIN (Q5EAB2) Cell division protein kinase 9 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9) Length = 372 Score = 82.4 bits (202), Expect = 8e-16 Identities = 51/148 (34%), Positives = 73/148 (49%) Frame = +3 Query: 111 KYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXX 290 KYEKL K+G+GT+G+V+KA + TGQ VALKK +E + EG P TALREI Sbjct: 18 KYEKLAKIGQGTFGEVFKAKHRKTGQKVALKKVLMENEKEGFPITALREI---KILQLLK 74 Query: 291 XXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKSF 470 +E K +YLVF+F + DL + +K Sbjct: 75 HENVVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLL-----SNVLVKFTLSEIKRV 129 Query: 471 LYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 + L G+ + H + +LHRD+K N+L+ Sbjct: 130 MQMLLNGLYYIHRNKILHRDMKAANVLI 157
>CDK10_HUMAN (Q15131) Cell division protein kinase 10 (EC 2.7.11.22)| (Serine/threonine-protein kinase PISSLRE) Length = 360 Score = 81.6 bits (200), Expect = 1e-15 Identities = 47/151 (31%), Positives = 78/151 (51%) Frame = +3 Query: 102 AMEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXX 281 +++++EKL ++GEGTYG VY+A D T ++VALKK R++ + +GIP ++LREI Sbjct: 35 SVKEFEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLRLR 94 Query: 282 XXXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVV 461 V ++LV + + DL ++ P P V Sbjct: 95 HPNIVELKEVV---------VGNHLESIFLVMGYCEQDLASLLE-----NMPTPFSEAQV 140 Query: 462 KSFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 K + Q+ +G+ + H + ++HRDLK NLL+ Sbjct: 141 KCIVLQVLRGLQYLHRNFIIHRDLKVSNLLM 171
>CDK4_XENLA (Q91727) Cell division protein kinase 4 (EC 2.7.11.22)| (Cyclin-dependent kinase 4) Length = 319 Score = 80.9 bits (198), Expect = 2e-15 Identities = 46/148 (31%), Positives = 74/148 (50%) Frame = +3 Query: 111 KYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXX 290 +YE + ++G G YG VYKA D +G+ VALK R++ ++ G+P + +RE+ Sbjct: 8 QYEPVAEIGVGAYGTVYKARDLQSGKFVALKNVRVQTNENGLPLSTVREV---TLLKRLE 64 Query: 291 XXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKSF 470 V+ + + LVFE +D DLK ++ P LP +K Sbjct: 65 HFDHPNIVKLMDVCASARTDRETKVTLVFEHVDQDLKTYLSKV----PPPGLPLETIKDL 120 Query: 471 LYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 + Q G+ H + ++HRDLKP+N+LV Sbjct: 121 MKQFLSGLEFLHLNCIVHRDLKPENILV 148
>CDK9A_XENLA (Q4V862) Cell division protein kinase 9-A (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9-A) Length = 376 Score = 80.9 bits (198), Expect = 2e-15 Identities = 48/151 (31%), Positives = 75/151 (49%), Gaps = 1/151 (0%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 + KYE+L K+G+GT+G+V+KA + TG+ VALKK +E + EG P TALREI Sbjct: 16 VSKYERLAKIGQGTFGEVFKAKHRQTGKKVALKKVLMENEKEGFPITALREIKILQLLKH 75 Query: 285 XXXXXXXXAVE-QTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVV 461 + + K ++LVF+F + DL + A + Sbjct: 76 ENVVNLIEICRTKVSPTANQYNRCKGTIFLVFDFCEHDLAGLL-----SNAHVKFTLSEI 130 Query: 462 KSFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 K + L G+ + H + +LHRD+K N+L+ Sbjct: 131 KKVMQMLLNGLYYIHRNKILHRDMKAANVLI 161
>CDK7_DICDI (P54685) Cell division protein kinase 7 (EC 2.7.11.22) (EC| 2.7.11.23) (CDK-activating kinase) (CAK) (MO15 homolog) Length = 362 Score = 80.5 bits (197), Expect = 3e-15 Identities = 56/154 (36%), Positives = 77/154 (50%), Gaps = 4/154 (2%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTR----LEMDDEGIPPTALREIXXXX 272 M+KY +GEGTYG V +A KATGQ+VA+KK R D+GI +A+REI Sbjct: 1 MDKYNIEALIGEGTYGVVSRATVKATGQIVAIKKIRKILIQNQTDDGINFSAIREIKILQ 60 Query: 273 XXXXXXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPT 452 K +YLVFE + DL++ ++ + KP Sbjct: 61 ELK-----------HDNVVNLLDIFAHKSNVYLVFELMQWDLQEVIE--DKSIILKPAD- 106 Query: 453 HVVKSFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 +KS++ L +GI CH + VLHRDLKP NLL+ Sbjct: 107 --IKSYMKMLLQGIEACHRNWVLHRDLKPNNLLM 138
>CDK9_XENTR (Q6GLD8) Cell division protein kinase 9 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9) Length = 376 Score = 80.5 bits (197), Expect = 3e-15 Identities = 48/151 (31%), Positives = 75/151 (49%), Gaps = 1/151 (0%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 + KYE+L K+G+GT+G+V+KA + TG+ VALKK +E + EG P TALREI Sbjct: 16 VSKYERLAKIGQGTFGEVFKAKHRQTGKKVALKKVLMENEKEGFPITALREIKILQLLKH 75 Query: 285 XXXXXXXXAVE-QTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVV 461 + + K ++LVF+F + DL + A + Sbjct: 76 ENVVNLIEICRTKISPTANQYNRCKGTIFLVFDFCEHDLAGLL-----SNAHVKFTLSEI 130 Query: 462 KSFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 K + L G+ + H + +LHRD+K N+L+ Sbjct: 131 KKVMQMLLNGLYYIHRNKILHRDMKAANVLI 161
>CDK9B_XENLA (Q7ZX42) Cell division protein kinase 9-B (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9-B) Length = 376 Score = 80.5 bits (197), Expect = 3e-15 Identities = 48/151 (31%), Positives = 75/151 (49%), Gaps = 1/151 (0%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 + KYE+L K+G+GT+G+V+KA + TG+ VALKK +E + EG P TALREI Sbjct: 16 VSKYERLAKIGQGTFGEVFKAKHRQTGKKVALKKVLMENEKEGFPITALREIKILQLLKH 75 Query: 285 XXXXXXXXAV-EQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVV 461 + + K ++LVF+F + DL + A + Sbjct: 76 ENVVHLIEICRNKISPTANQYNRCKGTIFLVFDFCEHDLAGLL-----SNAHVKFTVAEI 130 Query: 462 KSFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 K + L G+ + H + +LHRD+K N+L+ Sbjct: 131 KKVMQMLLNGLYYIHRNKILHRDMKAANVLI 161
>ERK1_DICDI (P42525) Extracellular signal-regulated kinase 1 (EC 2.7.11.24)| (ERK1) (MAP kinase 1) Length = 415 Score = 79.7 bits (195), Expect = 5e-15 Identities = 50/175 (28%), Positives = 76/175 (43%) Frame = +3 Query: 30 PPPSAPHXXXXXXXXXXXXXXXXSAMEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKT 209 PPP++ + +Y ++ +G G YG V A D TG+ VA+KK Sbjct: 3 PPPTSDTSNFNDNISYFVYGSQFTVPRRYSIVKCIGHGAYGVVCSAKDNLTGEKVAIKKI 62 Query: 210 RLEMDDEGIPPTALREIXXXXXXXXXXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLD 389 D+ LREI ++ +K +Y+V E +D Sbjct: 63 SKAFDNLKDTKRTLREIHLLRHFKHENLISIKDILKPNSKEQFED------VYIVSELMD 116 Query: 390 TDLKKFVDAYRRGPAPKPLPTHVVKSFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 TDL + + + P+PL + F+YQ+ +G+ H H VLHRDLKP NLL+ Sbjct: 117 TDLHQIITS------PQPLSDDHCQYFVYQMLRGLKHIHSANVLHRDLKPSNLLI 165
>CDKL3_HUMAN (Q8IVW4) Cyclin-dependent kinase-like 3 (EC 2.7.11.22)| (Serine/threonine protein kinase NKIAMRE) Length = 592 Score = 79.3 bits (194), Expect = 7e-15 Identities = 50/150 (33%), Positives = 74/150 (49%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 ME YE L KVGEG+YG V K K TGQ+VA+ K E ++ + A+REI Sbjct: 1 MEMYETLGKVGEGSYGTVMKCKHKNTGQIVAI-KIFYERPEQSVNKIAMREIKFLKQFHH 59 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 Q K ++LVFEF+D + + Y G K L + Sbjct: 60 ENLVNLIEVFRQKKK-----------IHLVFEFIDHTVLDELQHYCHGLESKRL-----R 103 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 +L+Q+ + I + H + ++HRD+KP+N+LV Sbjct: 104 KYLFQILRAIDYLHSNNIIHRDIKPENILV 133
>CDKL3_MACFA (Q4R8T9) Cyclin-dependent kinase-like 3 (EC 2.7.11.22)| Length = 590 Score = 79.3 bits (194), Expect = 7e-15 Identities = 50/150 (33%), Positives = 74/150 (49%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 ME YE L KVGEG+YG V K K TGQ+VA+ K E ++ + A+REI Sbjct: 1 MEMYETLGKVGEGSYGTVMKCKHKNTGQIVAI-KIFYERPEQSVNKIAMREIKFLKQFHH 59 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 Q K ++LVFEF+D + + Y G K L + Sbjct: 60 ENLVNLIEVFRQKKK-----------IHLVFEFIDHTVLDELQHYCHGLESKRL-----R 103 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 +L+Q+ + I + H + ++HRD+KP+N+LV Sbjct: 104 KYLFQILRAIDYLHSNNIIHRDIKPENILV 133
>CDK7_RAT (P51952) Cell division protein kinase 7 (EC 2.7.11.22) (EC| 2.7.11.23) (CDK-activating kinase) (CAK) (TFIIH basal transcription factor complex kinase subunit) (39 protein kinase) (P39 Mo15) (Fragment) Length = 329 Score = 78.6 bits (192), Expect = 1e-14 Identities = 53/149 (35%), Positives = 77/149 (51%), Gaps = 3/149 (2%) Frame = +3 Query: 117 EKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDE---GIPPTALREIXXXXXXXXX 287 EKL+ +GEG + VYKA DK T Q+VA+KK +L E GI TALREI Sbjct: 5 EKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHP 64 Query: 288 XXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKS 467 A K + LVF+F++TDL+ + + + P+H +K+ Sbjct: 65 NIIGLLDA-----------FGHKSNISLVFDFMETDLEVII----KDNSLVLTPSH-IKA 108 Query: 468 FLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 ++ +G+ + H H +LHRDLKP NLL+ Sbjct: 109 YMLMTLQGLEYLHQHWILHRDLKPNNLLL 137
>CDK7_XENLA (P20911) Cell division protein kinase 7 (EC 2.7.11.22) (EC| 2.7.11.23) (40 kDa protein kinase) (P40 MO15) (CDC2/CDK2,4-activating kinase) Length = 352 Score = 77.4 bits (189), Expect = 3e-14 Identities = 53/155 (34%), Positives = 80/155 (51%), Gaps = 3/155 (1%) Frame = +3 Query: 99 SAMEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRL---EMDDEGIPPTALREIXXX 269 S ++YEKL+ +GEG + VYKA DK T ++VA+KK +L ++GI TALREI Sbjct: 13 SRAKQYEKLDFLGEGQFATVYKARDKNTDRIVAIKKIKLGHRAEANDGINRTALREIKLL 72 Query: 270 XXXXXXXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLP 449 A K + LVF+F++TDL+ + + + P Sbjct: 73 QELSHPNIIGLLDA-----------FGHKSNISLVFDFMETDLEVII----KDTSLVLTP 117 Query: 450 THVVKSFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 H +KS++ +G+ + H +LHRDLKP NLL+ Sbjct: 118 AH-IKSYMLMTLQGLEYLHHLWILHRDLKPNNLLL 151
>CDK4_PIG (P79432) Cell division protein kinase 4 (EC 2.7.11.22)| (Cyclin-dependent kinase 4) Length = 303 Score = 77.0 bits (188), Expect = 3e-14 Identities = 48/155 (30%), Positives = 75/155 (48%), Gaps = 4/155 (2%) Frame = +3 Query: 102 AMEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDE---GIPPTALREIXXXX 272 A +YE + ++G G YG VYKA D +G VALK R+ G+P + +RE+ Sbjct: 2 ATSRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGAGGGLPISTVREVALLR 61 Query: 273 XXXXXXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKP-LP 449 ++ + + LVFE +D DL+ ++D AP P LP Sbjct: 62 RLEAFEHPNVVRLMDVCA---TARTDRETKVTLVFEHVDQDLRTYLDK-----APPPGLP 113 Query: 450 THVVKSFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 +K + Q +G+ H + ++HRDLKP+N+LV Sbjct: 114 VETIKDLMRQFLRGLDFLHANCIVHRDLKPENILV 148
>CDKL3_RAT (Q9JM01) Cyclin-dependent kinase-like 3 (EC 2.7.11.22)| (Serine/threonine protein kinase NKIATRE) Length = 593 Score = 76.6 bits (187), Expect = 4e-14 Identities = 49/150 (32%), Positives = 73/150 (48%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 ME YE L KVGEG+YG V K K TG++VA+ K E ++ + A REI Sbjct: 1 MEMYETLGKVGEGSYGTVMKCKHKDTGRIVAI-KIFYEKPEKSVNKIATREIKFLKQFRH 59 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 Q K ++LVFEF+D + + Y G K L + Sbjct: 60 ENLVNLIEVFRQKKK-----------IHLVFEFIDHTVLDELQHYCHGLESKRL-----R 103 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 +L+Q+ + I + H + ++HRD+KP+N+LV Sbjct: 104 KYLFQILRAIEYLHNNNIIHRDIKPENILV 133
>CDKL3_MOUSE (Q8BLF2) Cyclin-dependent kinase-like 3 (EC 2.7.11.22)| Length = 595 Score = 76.6 bits (187), Expect = 4e-14 Identities = 49/150 (32%), Positives = 73/150 (48%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 ME YE L KVGEG+YG V K K TG++VA+ K E ++ + A REI Sbjct: 1 MEMYETLGKVGEGSYGTVMKCKHKDTGRIVAI-KIFYEKPEKSVNKIATREIKFLKQFRH 59 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 Q K ++LVFEF+D + + Y G K L + Sbjct: 60 ENLVNLIEVFRQKKK-----------IHLVFEFIDHTVLDELQHYCHGLESKRL-----R 103 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 +L+Q+ + I + H + ++HRD+KP+N+LV Sbjct: 104 KYLFQILRAIEYLHNNNIIHRDIKPENILV 133
>CDK4_RAT (P35426) Cell division protein kinase 4 (EC 2.7.11.22)| (Cyclin-dependent kinase 4) (PSK-J3) Length = 303 Score = 76.3 bits (186), Expect = 6e-14 Identities = 48/155 (30%), Positives = 73/155 (47%), Gaps = 4/155 (2%) Frame = +3 Query: 102 AMEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDE---GIPPTALREIXXXX 272 A +YE + ++G G YG VYKA D +G VALK R+ G+P + +RE+ Sbjct: 2 ATTRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGAAGGGLPVSTVREVALLR 61 Query: 273 XXXXXXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKP-LP 449 ++ + LVFE +D DL+ ++D AP P LP Sbjct: 62 RLEAFEHPNVVRLMDVCATSRTDRDIK---VTLVFEHIDQDLRTYLDK-----APPPGLP 113 Query: 450 THVVKSFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 +K + Q G+ H + ++HRDLKP+N+LV Sbjct: 114 VETIKDLMRQFLSGLDFLHANCIVHRDLKPENILV 148
>CDK4_MOUSE (P30285) Cell division protein kinase 4 (EC 2.7.11.22)| (Cyclin-dependent kinase 4) (PSK-J3) (CRK3) Length = 303 Score = 76.3 bits (186), Expect = 6e-14 Identities = 48/155 (30%), Positives = 73/155 (47%), Gaps = 4/155 (2%) Frame = +3 Query: 102 AMEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDE---GIPPTALREIXXXX 272 A +YE + ++G G YG VYKA D +G VALK R+ G+P + +RE+ Sbjct: 2 AATRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGAAGGGLPVSTVREVALLR 61 Query: 273 XXXXXXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKP-LP 449 ++ + LVFE +D DL+ ++D AP P LP Sbjct: 62 RLEAFEHPNVVRLMDVCATSRTDRDIK---VTLVFEHIDQDLRTYLDK-----APPPGLP 113 Query: 450 THVVKSFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 +K + Q G+ H + ++HRDLKP+N+LV Sbjct: 114 VETIKDLMRQFLSGLDFLHANCIVHRDLKPENILV 148
>CDK4_HUMAN (P11802) Cell division protein kinase 4 (EC 2.7.11.22)| (Cyclin-dependent kinase 4) (PSK-J3) Length = 303 Score = 76.3 bits (186), Expect = 6e-14 Identities = 48/155 (30%), Positives = 74/155 (47%), Gaps = 4/155 (2%) Frame = +3 Query: 102 AMEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEG---IPPTALREIXXXX 272 A +YE + ++G G YG VYKA D +G VALK R+ G +P + +RE+ Sbjct: 2 ATSRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGGGGGLPISTVREVALLR 61 Query: 273 XXXXXXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKP-LP 449 ++ + LVFE +D DL+ ++D AP P LP Sbjct: 62 RLEAFEHPNVVRLMDVCATSRTDREIK---VTLVFEHVDQDLRTYLDK-----APPPGLP 113 Query: 450 THVVKSFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 +K + Q +G+ H + ++HRDLKP+N+LV Sbjct: 114 AETIKDLMRQFLRGLDFLHANCIVHRDLKPENILV 148
>CTK1_YEAST (Q03957) CTD kinase subunit alpha (EC 2.7.11.23) (CTD kinase 58 kDa| subunit) (CTDK-I alpha subunit) Length = 528 Score = 75.9 bits (185), Expect = 7e-14 Identities = 48/147 (32%), Positives = 75/147 (51%) Frame = +3 Query: 114 YEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXXX 293 Y ++ +VGEGTYGKVYKA + T ++VALKK RL+ + EG P T++REI Sbjct: 183 YLRIMQVGEGTYGKVYKAKNTNTEKLVALKKLRLQGEREGFPITSIREIKLLQSFDHPNV 242 Query: 294 XXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKSFL 473 + ++ K +Y++FE+ D DL + + H+ K Sbjct: 243 STIKEIMVESQK----------TVYMIFEYADNDLSGLL-LNKEVQISHSQCKHLFK--- 288 Query: 474 YQLCKGIAHCHGHGVLHRDLKPQNLLV 554 QL G+ + H + +LHRD+K N+L+ Sbjct: 289 -QLLLGMEYLHDNKILHRDVKGSNILI 314
>BUR1_YARLI (Q6C842) Serine/threonine-protein kinase BUR1 (EC 2.7.11.22) (EC| 2.7.11.23) Length = 706 Score = 75.9 bits (185), Expect = 7e-14 Identities = 49/149 (32%), Positives = 74/149 (49%) Frame = +3 Query: 108 EKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXX 287 E Y+ L K+GEGT+G+V++A T + VALKK L + EG P TALREI Sbjct: 36 ESYKPLGKIGEGTFGEVFRAEQITTKRHVALKKILLHSEKEGFPVTALREI---RILKLL 92 Query: 288 XXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKS 467 V+ + + +Y+V ++D DL + + + P H +K Sbjct: 93 RHENVIPLVDLAVERGDQSKKERGCVYMVTPYMDHDLAGLLG----NQSVQLSPAH-IKC 147 Query: 468 FLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 ++ QL +GI + H LHRD+K N+LV Sbjct: 148 YMLQLLEGIGYLHAKKFLHRDIKAANILV 176
>CDK9_SCHPO (Q96WV9) Serine/threonine-protein kinase cdk9 (EC 2.7.11.1)| (Cyclin-dependent kinase cdk9) Length = 591 Score = 75.1 bits (183), Expect = 1e-13 Identities = 47/152 (30%), Positives = 74/152 (48%) Frame = +3 Query: 99 SAMEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXX 278 S + Y +EK+GEGT+G+VYK+ + G+V ALK+ + + EG P TA+REI Sbjct: 31 SHLTDYHLMEKLGEGTFGEVYKSQRRKDGKVYALKRILMHTEKEGFPITAIREIKILKSI 90 Query: 279 XXXXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHV 458 + T + +Y+V ++D DL ++ P+ K Sbjct: 91 KHENIIPLS---DMTVVRADKKHRRRGSIYMVTPYMDHDLSGLLE----NPSVK-FTEPQ 142 Query: 459 VKSFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 +K ++ QL G + H +LHRDLK NLL+ Sbjct: 143 IKCYMKQLFAGTKYLHDQLILHRDLKAANLLI 174
>CDC2_PETHY (P43290) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) (Fragment) Length = 90 Score = 74.3 bits (181), Expect = 2e-13 Identities = 45/105 (42%), Positives = 55/105 (52%) Frame = +3 Query: 228 EGIPPTALREIXXXXXXXXXXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKF 407 EG+P TA+REI V + LYLVFE+LD DLKK Sbjct: 1 EGVPSTAIREISLLKEMQHANIVRLQDVVHSEKR-----------LYLVFEYLDLDLKKH 49 Query: 408 VDAYRRGPAPKPLPTHVVKSFLYQLCKGIAHCHGHGVLHRDLKPQ 542 +D+ P P +VK FLYQ+ +GIA+CH H VLHRDLKPQ Sbjct: 50 MDS---SPEFSKDP-RLVKMFLYQILRGIAYCHSHRVLHRDLKPQ 90
>CDK9_CAEEL (Q9TVL3) Probable cell division protein kinase 9 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9) Length = 478 Score = 73.9 bits (180), Expect = 3e-13 Identities = 48/147 (32%), Positives = 69/147 (46%) Frame = +3 Query: 114 YEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXXX 293 YEKL K+G+GT+G+V+KA K TG++VALKK +E + EG P TALRE+ Sbjct: 85 YEKLNKIGQGTFGEVFKARCKNTGRMVALKKILMENEKEGFPITALREV-KMLEQLKHPN 143 Query: 294 XXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKSFL 473 V + YLV DL + P + H +K+ + Sbjct: 144 ITDLIEVCSAKSTGTTGSKDRATFYLVMALCAHDLAGLLS----NPKIRMSLVH-IKTMM 198 Query: 474 YQLCKGIAHCHGHGVLHRDLKPQNLLV 554 L G+ H +LHRD+K N+L+ Sbjct: 199 KHLMSGLNKLHRSKILHRDMKAANVLI 225
>CRK1_SCHPO (Q12126) Serine/threonine-protein kinase crk1 (EC 2.7.11.23)| (Mitotic catastrophe suppressor 6) Length = 335 Score = 73.2 bits (178), Expect = 5e-13 Identities = 49/147 (33%), Positives = 69/147 (46%) Frame = +3 Query: 114 YEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXXX 293 Y K KVGEGTY V+ K T + VA+KK ++ +GI +ALREI Sbjct: 11 YVKERKVGEGTYAVVFLGRQKETNRRVAIKKIKVGQFKDGIDISALREIKFLRESR---- 66 Query: 294 XXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKSFL 473 K L ++ EFLD+DL+ + + P H +KS++ Sbjct: 67 -------HDNVIELVDVFSTKSNLNIILEFLDSDLEMLI----KDKFIVFQPAH-IKSWM 114 Query: 474 YQLCKGIAHCHGHGVLHRDLKPQNLLV 554 L +G+ H H +LHRDLKP NLL+ Sbjct: 115 VMLLRGLHHIHSRFILHRDLKPNNLLI 141
>MK07_MOUSE (Q9WVS8) Mitogen-activated protein kinase 7 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 5) (ERK-5) (BMK1 kinase) Length = 806 Score = 72.4 bits (176), Expect = 8e-13 Identities = 46/149 (30%), Positives = 70/149 (46%) Frame = +3 Query: 108 EKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXX 287 ++YE +E +G G YG V A + TGQ VA+KK D LRE+ Sbjct: 53 DEYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHD 112 Query: 288 XXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKS 467 ++ T +Y+V + +++DL + + + +PL V+ Sbjct: 113 NIIAIKDILKPTVPYGEFRS-----VYVVLDLMESDLHQIIHS------SQPLTLEHVRY 161 Query: 468 FLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 FLYQL +G+ + H V+HRDLKP NLLV Sbjct: 162 FLYQLLRGLKYMHSAQVIHRDLKPSNLLV 190
>MK07_HUMAN (Q13164) Mitogen-activated protein kinase 7 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 5) (ERK-5) (ERK4) (BMK1 kinase) Length = 815 Score = 72.0 bits (175), Expect = 1e-12 Identities = 46/149 (30%), Positives = 69/149 (46%) Frame = +3 Query: 108 EKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXX 287 ++YE +E +G G YG V A + TGQ VA+KK D LRE+ Sbjct: 52 DEYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHD 111 Query: 288 XXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKS 467 + T +Y+V + +++DL + + + +PL V+ Sbjct: 112 NIIAIKDILRPTVPYGEFKS-----VYVVLDLMESDLHQIIHS------SQPLTLEHVRY 160 Query: 468 FLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 FLYQL +G+ + H V+HRDLKP NLLV Sbjct: 161 FLYQLLRGLKYMHSAQVIHRDLKPSNLLV 189
>BUR1_CANAL (Q9Y7W4) Serine/threonine-protein kinase BUR1 (EC 2.7.11.22) (EC| 2.7.11.23) Length = 746 Score = 70.1 bits (170), Expect = 4e-12 Identities = 47/154 (30%), Positives = 71/154 (46%), Gaps = 2/154 (1%) Frame = +3 Query: 99 SAMEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXX 278 S ++ YE +EK+G+GT+G V KA K G +VA+K+ EG P TA+REI Sbjct: 39 SRLKDYEVIEKLGQGTFGVVQKAKSKKDGSLVAIKQLINHSAKEGFPITAMREITILKQL 98 Query: 279 XXXXXXXXXXAVEQTTKXX--XXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPT 452 + + K + Y V ++ +DL ++ P K L Sbjct: 99 NHKNILTIQDMIFEEPKMSNRTDIITMRGSFYTVTPYMSSDLVGLLE----NPKIK-LEL 153 Query: 453 HVVKSFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 +K + QL KGI + H LHRD+K N+L+ Sbjct: 154 GQIKCIMQQLLKGIQYVHNQKFLHRDIKAANILI 187
>MHK_ARATH (P43294) Serine/threonine-protein kinase MHK (EC 2.7.11.22)| Length = 443 Score = 69.3 bits (168), Expect = 7e-12 Identities = 48/152 (31%), Positives = 77/152 (50%), Gaps = 2/152 (1%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMD--DEGIPPTALREIXXXXXX 278 M +Y+ LE++G+GT G VYKA++ T +VVA+KK + + +E + LRE+ Sbjct: 9 MCRYKILEELGDGTCGSVYKAVNLETYEVVAVKKMKRKFYYWEECVN---LREVKALRKL 65 Query: 279 XXXXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHV 458 V + + L+ +FE +D +L + R P Sbjct: 66 NHPHIIKLKEIVREHNE-----------LFFIFECMDHNLYHIMKERER-----PFSEGE 109 Query: 459 VKSFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 ++SF+ Q+ +G+AH H +G HRDLKP+NLLV Sbjct: 110 IRSFMSQMLQGLAHMHKNGYFHRDLKPENLLV 141
>CDK8_DROME (Q9VT57) Cell division protein kinase 8 (EC 2.7.11.22) (EC| 2.7.11.23) (DmCdk8) Length = 454 Score = 68.9 bits (167), Expect = 9e-12 Identities = 51/147 (34%), Positives = 70/147 (47%), Gaps = 5/147 (3%) Frame = +3 Query: 129 KVGEGTYGKVYKAMDKAT--GQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXXXXXX 302 KVG GTYG VYKA K T G+ ALK ++D G+ +A REI Sbjct: 26 KVGRGTYGHVYKAKWKETSDGKEYALK----QIDGTGLSMSACREIALLRELKHQ----- 76 Query: 303 XXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKP---LPTHVVKSFL 473 T ++L+ ++ + DL + +R A K +P +VKS L Sbjct: 77 ----NVITLIRVFLSHNDRKVFLLIDYAEHDLWHIIKFHRAAKATKKQVVVPRGMVKSLL 132 Query: 474 YQLCKGIAHCHGHGVLHRDLKPQNLLV 554 YQ+ GI + H + VLHRDLKP N+LV Sbjct: 133 YQILDGIHYLHSNWVLHRDLKPANILV 159
>CD2L6_HUMAN (Q9BWU1) Cell division cycle 2-like protein kinase 6 (EC 2.7.11.22)| (CDC2-related protein kinase 6) (Death-preventing kinase) (Cyclin-dependent kinase 11) Length = 502 Score = 68.6 bits (166), Expect = 1e-11 Identities = 53/147 (36%), Positives = 71/147 (48%), Gaps = 5/147 (3%) Frame = +3 Query: 129 KVGEGTYGKVYKAM--DKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXXXXXX 302 KVG GTYG VYKA D + ALK +++ GI +A REI Sbjct: 26 KVGRGTYGHVYKARRKDGKDEKEYALK----QIEGTGISMSACREIALLRELKHPN---- 77 Query: 303 XXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPA---PKPLPTHVVKSFL 473 V K K ++L+F++ + DL + +R A P LP +VKS L Sbjct: 78 ---VIALQKVFLSHSDRK--VWLLFDYAEHDLWHIIKFHRASKANKKPMQLPRSMVKSLL 132 Query: 474 YQLCKGIAHCHGHGVLHRDLKPQNLLV 554 YQ+ GI + H + VLHRDLKP N+LV Sbjct: 133 YQILDGIHYLHANWVLHRDLKPANILV 159
>CD2L6_MOUSE (Q8BWD8) Cell division cycle 2-like protein kinase 6 (EC 2.7.11.22)| (CDC2-related protein kinase 6) Length = 501 Score = 68.6 bits (166), Expect = 1e-11 Identities = 53/147 (36%), Positives = 71/147 (48%), Gaps = 5/147 (3%) Frame = +3 Query: 129 KVGEGTYGKVYKAM--DKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXXXXXX 302 KVG GTYG VYKA D + ALK +++ GI +A REI Sbjct: 26 KVGRGTYGHVYKARRKDGKDEKEYALK----QIEGTGISMSACREIALLRELKHPN---- 77 Query: 303 XXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPA---PKPLPTHVVKSFL 473 V K K ++L+F++ + DL + +R A P LP +VKS L Sbjct: 78 ---VIALQKVFLSHSDRK--VWLLFDYAEHDLWHIIKFHRASKANKKPMQLPRSMVKSLL 132 Query: 474 YQLCKGIAHCHGHGVLHRDLKPQNLLV 554 YQ+ GI + H + VLHRDLKP N+LV Sbjct: 133 YQILDGIHYLHANWVLHRDLKPANILV 159
>MPK4_ARATH (Q39024) Mitogen-activated protein kinase homolog 4 (EC 2.7.11.24)| (MAP kinase 4) (AtMPK4) Length = 376 Score = 68.2 bits (165), Expect = 2e-11 Identities = 45/144 (31%), Positives = 66/144 (45%) Frame = +3 Query: 123 LEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXXXXXX 302 L +G G YG V A + TG+ VA+KK D+ LREI Sbjct: 46 LRPIGRGAYGIVCAATNSETGEEVAIKKIGNAFDNIIDAKRTLREIKLLKHMDHENVIAV 105 Query: 303 XXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKSFLYQL 482 ++ + +Y+V+E +DTDL + + + + PL + FLYQL Sbjct: 106 KDIIKPPQRENFND------VYIVYELMDTDLHQIIRSNQ------PLTDDHCRFFLYQL 153 Query: 483 CKGIAHCHGHGVLHRDLKPQNLLV 554 +G+ + H VLHRDLKP NLL+ Sbjct: 154 LRGLKYVHSANVLHRDLKPSNLLL 177
>CDK7_CARAU (P51953) Cell division protein kinase 7 (EC 2.7.11.22) (EC| 2.7.11.23) (40 kDa protein kinase) (P40 MO15) (CDC2/CDK2,4-activating kinase) Length = 344 Score = 68.2 bits (165), Expect = 2e-11 Identities = 48/155 (30%), Positives = 71/155 (45%), Gaps = 3/155 (1%) Frame = +3 Query: 99 SAMEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDE---GIPPTALREIXXX 269 S + YEKL+ +GEG + VYKA DK T +VA+KK ++ E GI TALREI Sbjct: 7 SRAKLYEKLDFLGEGQFATVYKARDKTTNTIVAIKKIKVGHRTEAKDGINRTALREIKLL 66 Query: 270 XXXXXXXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLP 449 A + + F++TDL+ + L Sbjct: 67 QELSHPNIIGLLDAFGHKSNIS------------LLCFMETDLEVIIK-----DTSLVLT 109 Query: 450 THVVKSFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 +K+++ +G+ + H H +LHRDLKP NLL+ Sbjct: 110 PANIKAYILMSLQGLEYMHNHWILHRDLKPNNLLL 144
>STY1_SCHPO (Q09892) Mitogen-activated protein kinase sty1 (EC 2.7.11.24) (MAP| kinase sty1) (MAP kinase spc1) Length = 349 Score = 68.2 bits (165), Expect = 2e-11 Identities = 43/148 (29%), Positives = 64/148 (43%) Frame = +3 Query: 111 KYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXX 290 +Y L+ +G G +G V A D+ TG VA+KK + RE+ Sbjct: 19 RYSDLQPIGMGAFGLVCSAKDQLTGMNVAVKKIMKPFSTPVLAKRTYRELKLLKHLRH-- 76 Query: 291 XXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKSF 470 E +Y V E L TDL + + + +PL T ++ F Sbjct: 77 --------ENIISLSDIFISPFEDIYFVTELLGTDLHRLLTS-------RPLETQFIQYF 121 Query: 471 LYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 LYQ+ +G+ H GV+HRDLKP N+L+ Sbjct: 122 LYQILRGLKFVHSAGVIHRDLKPSNILI 149
>CDK8_HUMAN (P49336) Cell division protein kinase 8 (EC 2.7.11.22) (EC| 2.7.11.23) (Protein kinase K35) Length = 464 Score = 68.2 bits (165), Expect = 2e-11 Identities = 53/147 (36%), Positives = 71/147 (48%), Gaps = 5/147 (3%) Frame = +3 Query: 129 KVGEGTYGKVYKAM--DKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXXXXXX 302 KVG GTYG VYKA D + ALK +++ GI +A REI Sbjct: 26 KVGRGTYGHVYKAKRKDGKDDKDYALK----QIEGTGISMSACREIALLRELKHPN---- 77 Query: 303 XXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPA---PKPLPTHVVKSFL 473 V K K ++L+F++ + DL + +R A P LP +VKS L Sbjct: 78 ---VISLQKVFLSHADRK--VWLLFDYAEHDLWHIIKFHRASKANKKPVQLPRGMVKSLL 132 Query: 474 YQLCKGIAHCHGHGVLHRDLKPQNLLV 554 YQ+ GI + H + VLHRDLKP N+LV Sbjct: 133 YQILDGIHYLHANWVLHRDLKPANILV 159
>MK12_BRARE (O42376) Mitogen-activated protein kinase 12 (EC 2.7.11.24)| (Stress-activated protein kinase 3) Length = 363 Score = 67.0 bits (162), Expect = 3e-11 Identities = 44/149 (29%), Positives = 64/149 (42%) Frame = +3 Query: 108 EKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXX 287 ++Y+ L++VG G YG V A+D+ TG VA+KK + A RE+ Sbjct: 23 DRYKDLKQVGTGAYGTVCYALDRRTGAKVAIKKLHRPFQSDLFAKRAYRELRLLKHMKHD 82 Query: 288 XXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKS 467 YLV F+ TDL K + R L V+ Sbjct: 83 NVIGLVDVFTADLSLDRFHD-----FYLVMPFMGTDLGKLMKMER-------LSEERVQY 130 Query: 468 FLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 +YQ+ KG+ + H G++HRDLKP NL + Sbjct: 131 LVYQMLKGLKYIHAAGIIHRDLKPGNLAI 159
>MK15_HUMAN (Q8TD08) Mitogen-activated protein kinase 15 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 8) Length = 544 Score = 67.0 bits (162), Expect = 3e-11 Identities = 48/150 (32%), Positives = 69/150 (46%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 + +Y ++G+G YG V+KA+D+ TG+VVA+KK D+ REI Sbjct: 10 VRRYLLRRQLGQGAYGIVWKAVDRRTGEVVAIKKIFDAFRDKTDAQRTFREITLLQEFGD 69 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 V + +YLVFEF+DTDL + R+G L V+ Sbjct: 70 HPNIISLLDVIRAENDRD--------IYLVFEFMDTDLNAVI---RKGGL---LQDVHVR 115 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 S YQL + H V+HRD KP N+L+ Sbjct: 116 SIFYQLLRATRFLHSGHVVHRDQKPSNVLL 145
>HOG1_CANAL (Q92207) Mitogen-activated protein kinase HOG1 (EC 2.7.11.24) (MAP| kinase HOG1) Length = 377 Score = 66.6 bits (161), Expect = 4e-11 Identities = 42/148 (28%), Positives = 65/148 (43%) Frame = +3 Query: 111 KYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXX 290 +Y +L VG G +G V A+D+ TGQ VA+KK + RE+ Sbjct: 22 RYTELNPVGMGAFGLVCSAVDRLTGQNVAVKKVMKPFSTSVLAKRTYRELKLLKHLKH-- 79 Query: 291 XXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKSF 470 E +Y V E TDL + +++ +PL ++ F Sbjct: 80 --------ENLITLDDIFISPLEDIYFVNELQGTDLHRLLNS-------RPLEKQFIQYF 124 Query: 471 LYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 YQ+ +G+ + H GV+HRDLKP N+L+ Sbjct: 125 TYQIMRGLKYIHSAGVIHRDLKPSNILI 152
>MAK_MOUSE (Q04859) Serine/threonine-protein kinase MAK (EC 2.7.11.22) (Male| germ cell-associated kinase) (Protein kinase RCK) Length = 622 Score = 66.6 bits (161), Expect = 4e-11 Identities = 41/151 (27%), Positives = 72/151 (47%), Gaps = 2/151 (1%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMD--DEGIPPTALREIXXXXXX 278 M +Y ++++G+GTYG V +G++VA+K+ + + DE + LRE+ Sbjct: 1 MNRYTTMKQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMN---LREVKSLKKL 57 Query: 279 XXXXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHV 458 + + LY VFE++ +L + + K P V Sbjct: 58 NHANVIKLKEVIRENDH-----------LYFVFEYMKENLYQLMKDRN-----KLFPESV 101 Query: 459 VKSFLYQLCKGIAHCHGHGVLHRDLKPQNLL 551 +++ +YQ+ +G+A H HG HRD+KP+NLL Sbjct: 102 IRNIMYQILQGLAFIHKHGFFHRDMKPENLL 132
>KIN28_YEAST (P06242) Serine/threonine-protein kinase KIN28 (EC 2.7.11.23)| Length = 306 Score = 66.6 bits (161), Expect = 4e-11 Identities = 44/147 (29%), Positives = 67/147 (45%) Frame = +3 Query: 111 KYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXX 290 +Y K +KVGEGTY VY +TG+ +A+K+ + +G+ +A+RE+ Sbjct: 6 EYTKEKKVGEGTYAVVYLGCQHSTGRKIAIKEIKTSEFKDGLDMSAIREVKYLQEMQ--- 62 Query: 291 XXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKSF 470 L LV EFL TDL+ + P +K++ Sbjct: 63 --------HPNVIELIDIFMAYDNLNLVLEFLPTDLEVVIKDKSILFTPAD-----IKAW 109 Query: 471 LYQLCKGIAHCHGHGVLHRDLKPQNLL 551 + +G+ HCH + +LHRDLKP NLL Sbjct: 110 MLMTLRGVYHCHRNFILHRDLKPNNLL 136
>MPK7_ARATH (Q39027) Mitogen-activated protein kinase homolog 7 (EC 2.7.11.24)| (MAP kinase 7) (AtMPK7) Length = 368 Score = 66.2 bits (160), Expect = 6e-11 Identities = 42/148 (28%), Positives = 68/148 (45%) Frame = +3 Query: 111 KYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXX 290 KY ++ +G G YG V ++++ T + VA+KK ++ LRE+ Sbjct: 31 KYVPIKPIGRGAYGVVCSSINRETNERVAIKKIHNVFENRVDALRTLRELKLLRHVRHEN 90 Query: 291 XXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKSF 470 + + +YLV+E +DTDL + + + + L K F Sbjct: 91 VIALKDVMLPANRSSFKD------VYLVYELMDTDLHQIIKS------SQSLSDDHCKYF 138 Query: 471 LYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 L+QL +G+ + H +LHRDLKP NLLV Sbjct: 139 LFQLLRGLKYLHSANILHRDLKPGNLLV 166
>MAK_HUMAN (P20794) Serine/threonine-protein kinase MAK (EC 2.7.11.22) (Male| germ cell-associated kinase) Length = 623 Score = 65.9 bits (159), Expect = 8e-11 Identities = 40/151 (26%), Positives = 71/151 (47%), Gaps = 2/151 (1%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMD--DEGIPPTALREIXXXXXX 278 M +Y + ++G+GTYG V +G++VA+K+ + + DE + LRE+ Sbjct: 1 MNRYTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMN---LREVKSLKKL 57 Query: 279 XXXXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHV 458 + + LY +FE++ +L + + K P V Sbjct: 58 NHANVIKLKEVIRENDH-----------LYFIFEYMKENLYQLMKDRN-----KLFPESV 101 Query: 459 VKSFLYQLCKGIAHCHGHGVLHRDLKPQNLL 551 +++ +YQ+ +G+A H HG HRD+KP+NLL Sbjct: 102 IRNIMYQILQGLAFIHKHGFFHRDMKPENLL 132
>MAK_RAT (P20793) Serine/threonine-protein kinase MAK (EC 2.7.11.22) (Male| germ cell-associated kinase) Length = 622 Score = 65.9 bits (159), Expect = 8e-11 Identities = 40/151 (26%), Positives = 71/151 (47%), Gaps = 2/151 (1%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMD--DEGIPPTALREIXXXXXX 278 M +Y + ++G+GTYG V +G++VA+K+ + + DE + LRE+ Sbjct: 1 MNRYTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMN---LREVKSLKKL 57 Query: 279 XXXXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHV 458 + + LY +FE++ +L + + K P V Sbjct: 58 NHANVIKLKEVIRENDH-----------LYFIFEYMKENLYQLMKDRN-----KLFPESV 101 Query: 459 VKSFLYQLCKGIAHCHGHGVLHRDLKPQNLL 551 +++ +YQ+ +G+A H HG HRD+KP+NLL Sbjct: 102 IRNIMYQILQGLAFIHKHGFFHRDMKPENLL 132
>MPK5_ARATH (Q39025) Mitogen-activated protein kinase homolog 5 (EC 2.7.11.24)| (MAP kinase 5) (AtMPK5) Length = 376 Score = 65.9 bits (159), Expect = 8e-11 Identities = 43/144 (29%), Positives = 65/144 (45%) Frame = +3 Query: 123 LEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXXXXXX 302 + +G G YG V A+D T + +A+KK D++ LREI Sbjct: 46 IRPIGRGAYGFVCAAVDSETHEEIAIKKIGKAFDNKVDAKRTLREIKLLRHLEHENVVVI 105 Query: 303 XXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKSFLYQL 482 + K +Y+VFE +DTDL + + + + L + FLYQ+ Sbjct: 106 KDIIRPPKKEDFVD------VYIVFELMDTDLHQIIRSNQS------LNDDHCQYFLYQI 153 Query: 483 CKGIAHCHGHGVLHRDLKPQNLLV 554 +G+ + H VLHRDLKP NLL+ Sbjct: 154 LRGLKYIHSANVLHRDLKPSNLLL 177
>MK13_RAT (Q9WTY9) Mitogen-activated protein kinase 13 (EC 2.7.11.24)| (Stress-activated protein kinase 4) (Mitogen-activated protein kinase p38 delta) (MAP kinase p38 delta) Length = 366 Score = 65.5 bits (158), Expect = 1e-10 Identities = 44/141 (31%), Positives = 58/141 (41%) Frame = +3 Query: 132 VGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXXXXXXXXA 311 VG G YG V A+DK TG+ VA+KK E A RE+ Sbjct: 31 VGSGAYGAVCSAIDKRTGEKVAIKKLSRPFQSEIFAKRAYRELLLLKHMHHENVIGLLDV 90 Query: 312 VEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKSFLYQLCKG 491 T YLV F+ TDL+K + V+ +YQ+ KG Sbjct: 91 YTPATSVRNFQD-----FYLVMPFMQTDLQKIMGM--------EFSEEKVQYLVYQMLKG 137 Query: 492 IAHCHGHGVLHRDLKPQNLLV 554 + + H G++HRDLKP NL V Sbjct: 138 LKYIHSAGIVHRDLKPGNLAV 158
>PIT1_SCHPO (O14132) Sporulation protein kinase pit1 (EC 2.7.11.1)| Length = 650 Score = 65.1 bits (157), Expect = 1e-10 Identities = 44/150 (29%), Positives = 68/150 (45%), Gaps = 1/150 (0%) Frame = +3 Query: 108 EKYEKLEKVGEGTYGKVYKAMDKATG-QVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 E Y + KVG+GT+G VY A K +VVA+K + ++ T LRE+ Sbjct: 34 EVYNVVRKVGDGTFGSVYLATTKTPSKEVVAIKSMKKKLAKVS-DATRLREVHSLLRLSE 92 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 E L++V EFLD +L + + + P L V+ Sbjct: 93 N---------ENIVNIFDLYIDQFRCLHIVMEFLDCNLYQLISTRKNDP----LTLEQVQ 139 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 + Q+ KG+ H H +G HRD+KP+N+L+ Sbjct: 140 DIMRQIFKGLNHIHTNGFFHRDMKPENILI 169
>MK12_MOUSE (O08911) Mitogen-activated protein kinase 12 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 6) (ERK-6) (Stress-activated protein kinase 3) (Mitogen-activated protein kinase p38 gamma) (MAP kinase p38 gamma) Length = 367 Score = 65.1 bits (157), Expect = 1e-10 Identities = 45/147 (30%), Positives = 60/147 (40%) Frame = +3 Query: 114 YEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXXX 293 Y+ L+ VG G YG V A+D TG VA+KK E A RE+ Sbjct: 27 YQDLQPVGSGAYGAVCSAVDSRTGNKVAIKKLYRPFQSELFAKRAYRELRLLKHMRHENV 86 Query: 294 XXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKSFL 473 YLV F+ TDL K + + L ++ + Sbjct: 87 IGLLDVFTPDESLDDFTD-----FYLVMPFMGTDLGKLMKH-------ETLSEDRIQFLV 134 Query: 474 YQLCKGIAHCHGHGVLHRDLKPQNLLV 554 YQ+ KG+ + H GV+HRDLKP NL V Sbjct: 135 YQMLKGLKYIHAAGVIHRDLKPGNLAV 161
>HOG1_DEBHA (Q9UV50) Mitogen-activated protein kinase HOG1 (EC 2.7.11.24) (MAP| kinase HOG1) Length = 387 Score = 64.7 bits (156), Expect = 2e-10 Identities = 43/148 (29%), Positives = 63/148 (42%) Frame = +3 Query: 111 KYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXX 290 +Y L VG G +G V A+DK TGQ VA+KK + RE+ Sbjct: 22 RYTDLNPVGMGAFGLVCSAIDKLTGQNVAVKKIMKPFLTSVLAKRTYRELKLLKHLRH-- 79 Query: 291 XXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKSF 470 E +Y V E TDL + + + +PL ++ F Sbjct: 80 --------ENLITLDDIFLSPLEDIYFVTELQGTDLHRLLTS-------RPLEKQFIQYF 124 Query: 471 LYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 YQ+ +G+ + H GV+HRDLKP N+L+ Sbjct: 125 TYQILRGLKYVHSAGVIHRDLKPSNILI 152
>MK12_RAT (Q63538) Mitogen-activated protein kinase 12 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 6) (ERK-6) (Stress-activated protein kinase 3) (Mitogen-activated protein kinase p38 gamma) (MAP kinase p38 gamma) Length = 367 Score = 64.7 bits (156), Expect = 2e-10 Identities = 45/147 (30%), Positives = 60/147 (40%) Frame = +3 Query: 114 YEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXXX 293 Y+ L+ VG G YG V A+D TG VA+KK E A RE+ Sbjct: 27 YQDLQPVGSGAYGAVCSAVDSRTGNKVAIKKLYRPFQSELFAKRAYRELRLLKHMRHENV 86 Query: 294 XXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKSFL 473 YLV F+ TDL K + + L ++ + Sbjct: 87 IGLLDVFTPDETLDDFTD-----FYLVMPFMGTDLGKLMKH-------ETLSEDRIQFLV 134 Query: 474 YQLCKGIAHCHGHGVLHRDLKPQNLLV 554 YQ+ KG+ + H GV+HRDLKP NL V Sbjct: 135 YQMLKGLKYIHAAGVIHRDLKPGNLAV 161
>ICK_RAT (Q62726) Serine/threonine-protein kinase ICK (EC 2.7.11.22)| (Intestinal cell kinase) (MAK-related kinase) (MRK) Length = 629 Score = 64.3 bits (155), Expect = 2e-10 Identities = 38/149 (25%), Positives = 68/149 (45%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 M +Y ++++G+GTYG V +G+++A+KK + + LRE+ Sbjct: 1 MNRYTTIKQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWE-ECMNLREVKSLKKLNH 59 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 + + LY +FE++ +L + + K P ++ Sbjct: 60 ANIVKLKEVIRENDH-----------LYFIFEYMKENLYQLIKERN-----KLFPESAIR 103 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLL 551 + +YQ+ +G+A H HG HRDLKP+NLL Sbjct: 104 NIMYQILQGLAFIHKHGFFHRDLKPENLL 132
>ICK_MOUSE (Q9JKV2) Serine/threonine-protein kinase ICK (EC 2.7.11.22)| (Intestinal cell kinase) (mICK) (MAK-related kinase) (MRK) Length = 629 Score = 64.3 bits (155), Expect = 2e-10 Identities = 38/149 (25%), Positives = 68/149 (45%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 M +Y ++++G+GTYG V +G+++A+KK + + LRE+ Sbjct: 1 MNRYTTIKQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWE-ECMNLREVKSLKKLNH 59 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 + + LY +FE++ +L + + K P ++ Sbjct: 60 ANIVKLKEVIRENDH-----------LYFIFEYMKENLYQLIKERN-----KLFPESAIR 103 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLL 551 + +YQ+ +G+A H HG HRDLKP+NLL Sbjct: 104 NIMYQILQGLAFIHKHGFFHRDLKPENLL 132
>MK13_MOUSE (Q9Z1B7) Mitogen-activated protein kinase 13 (EC 2.7.11.24)| (Stress-activated protein kinase 4) (Mitogen-activated protein kinase p38 delta) (MAP kinase p38 delta) Length = 366 Score = 63.9 bits (154), Expect = 3e-10 Identities = 43/141 (30%), Positives = 58/141 (41%) Frame = +3 Query: 132 VGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXXXXXXXXA 311 VG G YG V A+DK TG+ VA+KK E A RE+ Sbjct: 31 VGSGAYGAVCSAIDKRTGEKVAIKKLSRPFQSEIFAKRAYRELLLLKHMHHENVIGLLDV 90 Query: 312 VEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKSFLYQLCKG 491 + YLV F+ TDL+K + V+ +YQ+ KG Sbjct: 91 FTPASSLRSFHD-----FYLVMPFMQTDLQKIMGM--------EFSEDKVQYLVYQMLKG 137 Query: 492 IAHCHGHGVLHRDLKPQNLLV 554 + + H G++HRDLKP NL V Sbjct: 138 LKYIHSAGIVHRDLKPGNLAV 158
>MAPK_PETHY (Q40884) Mitogen-activated protein kinase homolog 1 (EC 2.7.11.24)| (PMEK1) Length = 384 Score = 63.9 bits (154), Expect = 3e-10 Identities = 40/148 (27%), Positives = 68/148 (45%) Frame = +3 Query: 111 KYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXX 290 KY ++ +G G YG V ++++ T + VA+KK ++ LRE+ Sbjct: 31 KYVPIKPIGRGAYGIVCSSVNRETNEKVAIKKINNAFENRIDALRTLRELKLLRHLRHEN 90 Query: 291 XXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKSF 470 + + +YLV+E +DTDL + + + + L + F Sbjct: 91 VIALKDVMMPIQRRSFKD------VYLVYELMDTDLHQIIKS------SQTLSNDHCQYF 138 Query: 471 LYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 L+QL +G+ + H +LHRDLKP NLL+ Sbjct: 139 LFQLLRGLKYLHSANILHRDLKPGNLLI 166
>MPK6_ARATH (Q39026) Mitogen-activated protein kinase homolog 6 (EC 2.7.11.24)| (MAP kinase 6) (AtMPK6) Length = 395 Score = 63.9 bits (154), Expect = 3e-10 Identities = 41/141 (29%), Positives = 64/141 (45%) Frame = +3 Query: 132 VGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXXXXXXXXA 311 +G+G YG V AM+ T + VA+KK D++ LREI Sbjct: 69 IGKGAYGIVCSAMNSETNESVAIKKIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDI 128 Query: 312 VEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKSFLYQLCKG 491 + + +Y+ +E +DTDL + + + + L + FLYQ+ +G Sbjct: 129 IPPPLRNAFND------VYIAYELMDTDLHQIIRSNQA------LSEEHCQYFLYQILRG 176 Query: 492 IAHCHGHGVLHRDLKPQNLLV 554 + + H VLHRDLKP NLL+ Sbjct: 177 LKYIHSANVLHRDLKPSNLLL 197
>ICK_HUMAN (Q9UPZ9) Serine/threonine-protein kinase ICK (EC 2.7.11.22)| (Intestinal cell kinase) (hICK) (MAK-related kinase) (MRK) (Laryngeal cancer kinase 2) (LCK2) Length = 632 Score = 63.9 bits (154), Expect = 3e-10 Identities = 38/149 (25%), Positives = 67/149 (44%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 M +Y + ++G+GTYG V +G+++A+KK + + LRE+ Sbjct: 1 MNRYTTIRQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWE-ECMNLREVKSLKKLNH 59 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 + + LY +FE++ +L + + K P ++ Sbjct: 60 ANVVKLKEVIRENDH-----------LYFIFEYMKENLYQLIKERN-----KLFPESAIR 103 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLL 551 + +YQ+ +G+A H HG HRDLKP+NLL Sbjct: 104 NIMYQILQGLAFIHKHGFFHRDLKPENLL 132
>MMK2_MEDSA (Q40353) Mitogen-activated protein kinase homolog MMK2 (EC| 2.7.11.24) Length = 371 Score = 63.5 bits (153), Expect = 4e-10 Identities = 43/144 (29%), Positives = 64/144 (44%) Frame = +3 Query: 123 LEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXXXXXX 302 + VG G YG V A++ T + VA+KK D+ LREI Sbjct: 40 IRSVGRGAYGIVCAAVNAETREEVAIKKIGNAFDNRIDAKRTLREIKLLRHMDHENVMSI 99 Query: 303 XXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKSFLYQL 482 + K +Y+V E +DTDL + + + + P+ + F+YQL Sbjct: 100 KDIIRPPQKENFNH------VYIVSELMDTDLHQIIRSNQ------PMTDDHCRYFVYQL 147 Query: 483 CKGIAHCHGHGVLHRDLKPQNLLV 554 +G+ + H VLHRDLKP NLL+ Sbjct: 148 LRGLKYVHSANVLHRDLKPSNLLL 171
>NTF3_TOBAC (Q40517) Mitogen-activated protein kinase homolog NTF3 (EC| 2.7.11.24) (P43) Length = 372 Score = 63.5 bits (153), Expect = 4e-10 Identities = 40/148 (27%), Positives = 68/148 (45%) Frame = +3 Query: 111 KYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXX 290 KY ++ +G G YG V ++++ T + VA+KK ++ LRE+ Sbjct: 31 KYVPIKPIGRGAYGIVCSSVNRETNEKVAIKKINNAFENRIDALRTLRELKLLRHLRHEN 90 Query: 291 XXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKSF 470 + + +YLV+E +DTDL + + + + L + F Sbjct: 91 VIALKDVMMPIHRRSFKD------VYLVYELMDTDLHQIIKS------SQTLSNDHCQYF 138 Query: 471 LYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 L+QL +G+ + H +LHRDLKP NLL+ Sbjct: 139 LFQLLRGLKYLHSANILHRDLKPGNLLI 166
>HOG1_YEAST (P32485) Mitogen-activated protein kinase HOG1 (EC 2.7.11.24) (MAP| kinase HOG1) (Osmosensing protein HOG1) Length = 435 Score = 63.2 bits (152), Expect = 5e-10 Identities = 43/148 (29%), Positives = 60/148 (40%) Frame = +3 Query: 111 KYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXX 290 +Y L VG G +G V A D T Q VA+KK + RE+ Sbjct: 22 RYNDLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTAVLAKRTYRELKLLKHLRH-- 79 Query: 291 XXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKSF 470 E +Y V E TDL + + +PL V+ F Sbjct: 80 --------ENLICLQDIFLSPLEDIYFVTELQGTDLHRLLQT-------RPLEKQFVQYF 124 Query: 471 LYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 LYQ+ +G+ + H GV+HRDLKP N+L+ Sbjct: 125 LYQILRGLKYVHSAGVIHRDLKPSNILI 152
>MPK1_ARATH (Q39021) Mitogen-activated protein kinase homolog 1 (EC 2.7.11.24)| (MAP kinase 1) (AtMPK1) Length = 370 Score = 63.2 bits (152), Expect = 5e-10 Identities = 42/148 (28%), Positives = 67/148 (45%) Frame = +3 Query: 111 KYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXX 290 KY ++ +G G YG V +++ T + VA+KK ++ LRE+ Sbjct: 31 KYMPIKPIGRGAYGVVCSSVNSDTNEKVAIKKIHNVYENRIDALRTLRELKLLRHLRHEN 90 Query: 291 XXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKSF 470 + K +YLV+E +DTDL + + + + L + F Sbjct: 91 VIALKDVMMPIHKMSFKD------VYLVYELMDTDLHQIIKS------SQVLSNDHCQYF 138 Query: 471 LYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 L+QL +G+ + H +LHRDLKP NLLV Sbjct: 139 LFQLLRGLKYIHSANILHRDLKPGNLLV 166
>MOK_MOUSE (Q9WVS4) MAPK/MAK/MRK overlapping kinase (EC 2.7.11.22) (MOK| protein kinase) Length = 420 Score = 63.2 bits (152), Expect = 5e-10 Identities = 42/151 (27%), Positives = 68/151 (45%), Gaps = 1/151 (0%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDD-EGIPPTALREIXXXXXXX 281 M+ Y+ + K+GEGT+ +V K G A K+ + + E + +LREI Sbjct: 1 MKNYKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQHFESIEQV--NSLREIQALRRLN 58 Query: 282 XXXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVV 461 V K L L+ E +D ++ + + R PL + Sbjct: 59 PHPNILALHEVVFDRKSGS--------LALICELMDMNIYELIRGRRH-----PLSEKKI 105 Query: 462 KSFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 ++YQLCK + H H +G+ HRD+KP+N+LV Sbjct: 106 MLYMYQLCKSLDHMHRNGIFHRDVKPENILV 136
>HOG1_ZYGRO (O93982) Mitogen-activated protein kinase HOG1 (EC 2.7.11.24) (MAP| kinase HOG1) Length = 380 Score = 63.2 bits (152), Expect = 5e-10 Identities = 43/148 (29%), Positives = 60/148 (40%) Frame = +3 Query: 111 KYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXX 290 +Y L VG G +G V A D GQ VA+KK + RE+ Sbjct: 22 RYTDLNPVGMGAFGLVCSATDTLAGQPVAIKKIMKPFSTAVLAKRTYRELKLLKHLRH-- 79 Query: 291 XXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKSF 470 E +Y V E TDL + + +PL V+ F Sbjct: 80 --------ENLICLQDIFLSPLEDIYFVTELQGTDLHRLLQT-------RPLEKQFVQYF 124 Query: 471 LYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 LYQ+ +G+ + H GV+HRDLKP N+L+ Sbjct: 125 LYQILRGLKYVHSAGVIHRDLKPSNILI 152
>MPK2_ARATH (Q39022) Mitogen-activated protein kinase homolog 2 (EC 2.7.11.24)| (MAP kinase 2) (AtMPK2) Length = 376 Score = 63.2 bits (152), Expect = 5e-10 Identities = 41/148 (27%), Positives = 68/148 (45%) Frame = +3 Query: 111 KYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXX 290 KY ++ +G G YG V ++++ + + VA+KK ++ LRE+ Sbjct: 31 KYVPIKPIGRGAYGVVCSSVNRESNERVAIKKIHNVFENRIDALRTLRELKLLRHLRHEN 90 Query: 291 XXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKSF 470 + K +YLV+E +DTDL + + + + L + F Sbjct: 91 VVALKDVMMANHKRSFKD------VYLVYELMDTDLHQIIKS------SQVLSNDHCQYF 138 Query: 471 LYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 L+QL +G+ + H +LHRDLKP NLLV Sbjct: 139 LFQLLRGLKYIHSANILHRDLKPGNLLV 166
>MK13_PANTR (Q9N272) Mitogen-activated protein kinase 13 (EC 2.7.11.24)| (Stress-activated protein kinase 4) Length = 365 Score = 62.8 bits (151), Expect = 6e-10 Identities = 42/141 (29%), Positives = 58/141 (41%) Frame = +3 Query: 132 VGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXXXXXXXXA 311 VG G YG V A+DK +G+ VA+KK E A RE+ Sbjct: 31 VGSGAYGSVCSAIDKRSGEKVAIKKLSRPFQSEIFAKRAYRELLLLKHMQHENVIGLLDV 90 Query: 312 VEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKSFLYQLCKG 491 + YLV F+ TDL+K + ++ +YQ+ KG Sbjct: 91 FTPASSLRNFHD-----FYLVMXFMQTDLQKIMXM--------EFSEEKIQYLVYQMLKG 137 Query: 492 IAHCHGHGVLHRDLKPQNLLV 554 + + H GV+HRDLKP NL V Sbjct: 138 LKYIHSAGVVHRDLKPGNLAV 158
>MK13_HUMAN (O15264) Mitogen-activated protein kinase 13 (EC 2.7.11.24)| (Stress-activated protein kinase 4) (Mitogen-activated protein kinase p38 delta) (MAP kinase p38 delta) Length = 365 Score = 62.8 bits (151), Expect = 6e-10 Identities = 42/141 (29%), Positives = 58/141 (41%) Frame = +3 Query: 132 VGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXXXXXXXXA 311 VG G YG V A+DK +G+ VA+KK E A RE+ Sbjct: 31 VGSGAYGSVCSAIDKRSGEKVAIKKLSRPFQSEIFAKRAYRELLLLKHMQHENVIGLLDV 90 Query: 312 VEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKSFLYQLCKG 491 + YLV F+ TDL+K + ++ +YQ+ KG Sbjct: 91 FTPASSLRNFYD-----FYLVMPFMQTDLQKIMGM--------EFSEEKIQYLVYQMLKG 137 Query: 492 IAHCHGHGVLHRDLKPQNLLV 554 + + H GV+HRDLKP NL V Sbjct: 138 LKYIHSAGVVHRDLKPGNLAV 158
>MK12_HUMAN (P53778) Mitogen-activated protein kinase 12 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 6) (ERK-6) (ERK5) (Stress-activated protein kinase 3) (Mitogen-activated protein kinase p38 gamma) (MAP kinase p38 gamma) Length = 367 Score = 62.8 bits (151), Expect = 6e-10 Identities = 44/147 (29%), Positives = 59/147 (40%) Frame = +3 Query: 114 YEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXXX 293 Y L+ VG G YG V A+D TG VA+KK E A RE+ Sbjct: 27 YRDLQPVGSGAYGAVCSAVDGRTGAKVAIKKLYRPFQSELFAKRAYRELRLLKHMRHENV 86 Query: 294 XXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKSFL 473 YLV F+ TDL K + + G ++ + Sbjct: 87 IGLLDVFTPDETLDDFTD-----FYLVMPFMGTDLGKLMKHEKLGEDR-------IQFLV 134 Query: 474 YQLCKGIAHCHGHGVLHRDLKPQNLLV 554 YQ+ KG+ + H G++HRDLKP NL V Sbjct: 135 YQMLKGLRYIHAAGIIHRDLKPGNLAV 161
>MKH1_SCHPO (Q10407) MAP kinase kinase kinase mkh1 (EC 2.7.11.25)| Length = 1116 Score = 62.4 bits (150), Expect = 8e-10 Identities = 42/158 (26%), Positives = 71/158 (44%), Gaps = 6/158 (3%) Frame = +3 Query: 99 SAMEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXX 278 +A K+ K E +G GTYGKV+ AM+ TG+++A+K+ + G ++I Sbjct: 820 NATFKWMKGELIGNGTYGKVFLAMNINTGELIAVKQVEIPQTINGRHDQLRKDI------ 873 Query: 279 XXXXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPK------ 440 ++ V YL FE +TD+ F++ G + Sbjct: 874 --------VDSINAEISMIADLDHLNIVQYLGFEKTETDISIFLEYVSGGSIGRCLRNYG 925 Query: 441 PLPTHVVKSFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 P +V+ Q+ G+++ H G++HRDLK NLL+ Sbjct: 926 PFEEQLVRFVSRQVLYGLSYLHSKGIIHRDLKADNLLI 963
>BUR1_DEBHA (Q6BV06) Serine/threonine-protein kinase BUR1 (EC 2.7.11.22) (EC| 2.7.11.23) Length = 608 Score = 62.4 bits (150), Expect = 8e-10 Identities = 45/154 (29%), Positives = 71/154 (46%), Gaps = 2/154 (1%) Frame = +3 Query: 99 SAMEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXX 278 S + YE ++K+G+GT+G V KA + T ++VALK+ EG P TA+REI Sbjct: 34 SKLRNYEIIQKLGQGTFGVVQKARNIKTKELVALKQLINHSAKEGFPITAMREITILKKL 93 Query: 279 XXXXXXXXXXAVEQTTKXX--XXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPT 452 + + K + Y V ++ +DL ++ P + Sbjct: 94 NHKNILKIIDMIYEEPKISNPQDILHQRGCFYTVSPYMCSDLVGLLE----NPNINLEVS 149 Query: 453 HVVKSFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 H +K F+ QL GI + H LHRD+K N+L+ Sbjct: 150 H-IKCFMEQLLHGIQYIHEQMFLHRDIKAANILI 182
>PRK1_SCHPO (O13958) Serine/threonine-protein kinase prk1 (EC 2.7.11.22)| (Suppressor of RNA polymerase B srb10) Length = 352 Score = 62.4 bits (150), Expect = 8e-10 Identities = 39/156 (25%), Positives = 74/156 (47%), Gaps = 9/156 (5%) Frame = +3 Query: 114 YEKLEKVGEGTYGKVYKAMDKATG--QVVALKKTRLEM-------DDEGIPPTALREIXX 266 Y+ + + GTYGKVYKA+ + ++ A+KK + E G+ +A+RE+ Sbjct: 5 YKIIGFISSGTYGKVYKAVSSNSNDKRLFAIKKFKAESKQVSSNAQQTGVSQSAIREMML 64 Query: 267 XXXXXXXXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPL 446 + + +VFE+ + DL + + + R + + Sbjct: 65 CREIQ-----------HENIVSLVQVLLKDGTISMVFEYAEHDLLQIIHFHSRSRT-RQI 112 Query: 447 PTHVVKSFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 P ++KS L+Q+ G+A+ H + ++HRDLKP N+++ Sbjct: 113 PPSILKSILWQIINGVAYLHENWIMHRDLKPANIMI 148
>NTF4_TOBAC (Q40532) Mitogen-activated protein kinase homolog NTF4 (EC| 2.7.11.24) (P45) Length = 393 Score = 62.0 bits (149), Expect = 1e-09 Identities = 40/141 (28%), Positives = 64/141 (45%) Frame = +3 Query: 132 VGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXXXXXXXXA 311 +G+G YG V A++ T + VA+KK D++ LREI Sbjct: 66 IGKGAYGIVCSALNSETNEHVAIKKIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDI 125 Query: 312 VEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKSFLYQLCKG 491 + + +Y+ +E +DTDL + + + + L + FLYQ+ +G Sbjct: 126 IPPPQREAFND------VYIAYELMDTDLHQIIRSNQG------LSEEHCQYFLYQILRG 173 Query: 492 IAHCHGHGVLHRDLKPQNLLV 554 + + H VLHRDLKP NLL+ Sbjct: 174 LKYIHSANVLHRDLKPSNLLL 194
>NTF6_TOBAC (Q40531) Mitogen-activated protein kinase homolog NTF6 (EC| 2.7.11.24) (P43) Length = 371 Score = 62.0 bits (149), Expect = 1e-09 Identities = 43/144 (29%), Positives = 64/144 (44%) Frame = +3 Query: 123 LEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXXXXXX 302 ++ VG G YG V A + T + VA+KK ++ LREI Sbjct: 41 IQPVGRGAYGMVCCATNSETKEEVAIKKIGNAFENRIDAKRTLREIKLLSHMDHENIIKI 100 Query: 303 XXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKSFLYQL 482 V + +Y+V+E +DTDL + + + + L + FLYQL Sbjct: 101 KDIVRPPDREEFND------VYIVYELMDTDLHQIIRS------SQALTDDHCQYFLYQL 148 Query: 483 CKGIAHCHGHGVLHRDLKPQNLLV 554 +G+ + H VLHRDLKP NLL+ Sbjct: 149 LRGLKYVHSANVLHRDLKPSNLLL 172
>MOK_HUMAN (Q9UQ07) MAPK/MAK/MRK overlapping kinase (EC 2.7.11.22) (MOK| protein kinase) (Renal tumor antigen 1) (RAGE-1) Length = 419 Score = 61.6 bits (148), Expect = 1e-09 Identities = 43/152 (28%), Positives = 67/152 (44%), Gaps = 2/152 (1%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALK--KTRLEMDDEGIPPTALREIXXXXXX 278 M+ Y+ + K+GEGT+ +V K G A K K R E ++ LREI Sbjct: 1 MKNYKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQRFESIEQ---VNNLREIQALRRL 57 Query: 279 XXXXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHV 458 V K L L+ E +D ++ + + R PL Sbjct: 58 NPHPNILMLHEVVFDRKSGS--------LALICELMDMNIYELIRGRRY-----PLSEKK 104 Query: 459 VKSFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 + ++YQLCK + H H +G+ HRD+KP+N+L+ Sbjct: 105 IMHYMYQLCKSLDHIHRNGIFHRDVKPENILI 136
>MPK3_ARATH (Q39023) Mitogen-activated protein kinase homolog 3 (EC 2.7.11.24)| (MAP kinase 3) (AtMPK3) Length = 370 Score = 61.2 bits (147), Expect = 2e-09 Identities = 40/141 (28%), Positives = 61/141 (43%) Frame = +3 Query: 132 VGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXXXXXXXXA 311 +G G YG V +D T ++VA+KK D+ LREI Sbjct: 44 IGRGAYGIVCSVLDTETNELVAMKKIANAFDNHMDAKRTLREIKLLRHLDHENIIAIRDV 103 Query: 312 VEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKSFLYQLCKG 491 V + +Y+ E +DTDL + + + + L + FLYQL +G Sbjct: 104 VPPPLRRQFSD------VYISTELMDTDLHQIIRSNQS------LSEEHCQYFLYQLLRG 151 Query: 492 IAHCHGHGVLHRDLKPQNLLV 554 + + H ++HRDLKP NLL+ Sbjct: 152 LKYIHSANIIHRDLKPSNLLL 172
>HOG1_ASHGO (Q750A9) Mitogen-activated protein kinase HOG1 (EC 2.7.11.24) (MAP| kinase HOG1) Length = 447 Score = 61.2 bits (147), Expect = 2e-09 Identities = 42/148 (28%), Positives = 61/148 (41%) Frame = +3 Query: 111 KYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXX 290 +Y L VG G +G V A+D T Q VA+KK + RE+ Sbjct: 22 RYADLNPVGMGAFGLVCSAVDTYTQQPVAIKKIMKPFSTAVLAKRTYRELKLLKHLRH-- 79 Query: 291 XXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKSF 470 E +Y V E TDL + + +PL ++ F Sbjct: 80 --------ENLICLEDIFLSPLEDIYFVTELQGTDLHRLLQT-------RPLEKQFLQYF 124 Query: 471 LYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 LYQ+ +G+ + H GV+HRDLKP N+L+ Sbjct: 125 LYQILRGLKYVHSAGVIHRDLKPSNILI 152
>SUR1_CAEEL (P39745) Mitogen-activated protein kinase mpk-1 (EC 2.7.11.24) (MAP| kinase sur-1) Length = 444 Score = 61.2 bits (147), Expect = 2e-09 Identities = 45/148 (30%), Positives = 63/148 (42%) Frame = +3 Query: 111 KYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXX 290 +Y L +GEG YG V A+D T VA+KK + + LREI Sbjct: 95 RYVNLSYIGEGAYGMVASALDTITRDRVAIKKIS-PFEHQTFCQRTLREIKILNRFKHEN 153 Query: 291 XXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKSF 470 + T +Y+V ++TDL K + + L V F Sbjct: 154 IINIQEIIRSETVDSLKD------IYIVQCLMETDLYKLLKTQK-------LSNDHVCYF 200 Query: 471 LYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 LYQ+ +G+ + H VLHRDLKP NLL+ Sbjct: 201 LYQILRGLKYIHSANVLHRDLKPSNLLL 228
>MK03_HUMAN (P27361) Mitogen-activated protein kinase 3 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 1) (ERK-1) (Insulin-stimulated MAP2 kinase) (MAP kinase 1) (MAPK 1) (p44-ERK1) (ERT2) (p44-MAPK) (Microtubule-associated protein 2 kinase) Length = 379 Score = 60.8 bits (146), Expect = 2e-09 Identities = 43/148 (29%), Positives = 66/148 (44%) Frame = +3 Query: 111 KYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXX 290 +Y +L+ +GEG YG V A D VA+KK + + LREI Sbjct: 41 RYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKIS-PFEHQTYCQRTLREIQILLRFRHEN 99 Query: 291 XXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKSF 470 + +T +Y+V + ++TDL K + + + L + F Sbjct: 100 VIGIRDILRASTLEAMRD------VYIVQDLMETDLYKLLKSQQ-------LSNDHICYF 146 Query: 471 LYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 LYQ+ +G+ + H VLHRDLKP NLL+ Sbjct: 147 LYQILRGLKYIHSANVLHRDLKPSNLLI 174
>NLK_MOUSE (O54949) Serine/threonine kinase NLK (EC 2.7.11.24) (Nemo-like| kinase) Length = 515 Score = 60.8 bits (146), Expect = 2e-09 Identities = 41/141 (29%), Positives = 63/141 (44%) Frame = +3 Query: 132 VGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXXXXXXXXA 311 +G G +G V+ D G+ VALKK + RE+ Sbjct: 132 IGYGAFGVVWSVTDPRDGKRVALKKMPNVFQNLVSCKRVFRELKMLCFFKHDNVLSALDI 191 Query: 312 VEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKSFLYQLCKG 491 ++ +Y+V E + +DL K + +P+PL + VK FLYQ+ +G Sbjct: 192 LQPPHIDYFEE------IYVVTELMQSDLHKII------VSPQPLSSDHVKVFLYQILRG 239 Query: 492 IAHCHGHGVLHRDLKPQNLLV 554 + + H G+LHRD+KP NLLV Sbjct: 240 LKYLHSAGILHRDIKPGNLLV 260
>NLK_HUMAN (Q9UBE8) Serine/threonine kinase NLK (EC 2.7.11.24) (Nemo-like| kinase) (LAK1 protein) Length = 515 Score = 60.8 bits (146), Expect = 2e-09 Identities = 41/141 (29%), Positives = 63/141 (44%) Frame = +3 Query: 132 VGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXXXXXXXXA 311 +G G +G V+ D G+ VALKK + RE+ Sbjct: 132 IGYGAFGVVWSVTDPRDGKRVALKKMPNVFQNLVSCKRVFRELKMLCFFKHDNVLSALDI 191 Query: 312 VEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKSFLYQLCKG 491 ++ +Y+V E + +DL K + +P+PL + VK FLYQ+ +G Sbjct: 192 LQPPHIDYFEE------IYVVTELMQSDLHKII------VSPQPLSSDHVKVFLYQILRG 239 Query: 492 IAHCHGHGVLHRDLKPQNLLV 554 + + H G+LHRD+KP NLLV Sbjct: 240 LKYLHSAGILHRDIKPGNLLV 260
>STK36_MOUSE (Q69ZM6) Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused| homolog) Length = 1268 Score = 60.8 bits (146), Expect = 2e-09 Identities = 46/150 (30%), Positives = 64/150 (42%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 MEKY LE +GEG++G+VYK K + QVVALK E REI Sbjct: 1 MEKYHVLEMIGEGSFGRVYKGRKKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLWH 60 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 + E + + L F+ L+ D K LP V+ Sbjct: 61 PNIVHMLDSFETDKEVVVVTDYAEGEL---FQILEDDGK--------------LPEDQVQ 103 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 + QL + + H H +LHRD+KPQN+L+ Sbjct: 104 AIAAQLVSALYYLHSHRILHRDMKPQNILL 133
>SNF1_CANAL (P52497) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 620 Score = 60.8 bits (146), Expect = 2e-09 Identities = 45/152 (29%), Positives = 70/152 (46%), Gaps = 4/152 (2%) Frame = +3 Query: 111 KYEKLEKVGEGTYGKVYKAMDKATGQVVALK----KTRLEMDDEGIPPTALREIXXXXXX 278 +Y+ L+ +GEG++GKV A TGQ VALK KT + D +G REI Sbjct: 52 RYQILKTLGEGSFGKVKLAQHLGTGQKVALKIINRKTLAKSDMQG---RVEREISYLRLL 108 Query: 279 XXXXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHV 458 ++ K + +V EF +L ++ +RG +P Sbjct: 109 RHPHIIKLYDVIKS-----------KDEIIMVIEFAGKELFDYI--VQRGK----MPEDE 151 Query: 459 VKSFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 + F Q+ + +CH H ++HRDLKP+NLL+ Sbjct: 152 ARRFFQQIIAAVEYCHRHKIVHRDLKPENLLL 183
>STK36_HUMAN (Q9NRP7) Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused| homolog) Length = 1315 Score = 60.8 bits (146), Expect = 2e-09 Identities = 46/150 (30%), Positives = 64/150 (42%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 MEKY LE +GEG++G+VYK K + QVVALK E REI Sbjct: 1 MEKYHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLRH 60 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 + E + + L F+ L+ D K LP V+ Sbjct: 61 PNIVHMLDSFETDKEVVVVTDYAEGEL---FQILEDDGK--------------LPEDQVQ 103 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 + QL + + H H +LHRD+KPQN+L+ Sbjct: 104 AIAAQLVSALYYLHSHRILHRDMKPQNILL 133
>MMK1_MEDSA (Q07176) Mitogen-activated protein kinase homolog MMK1 (EC| 2.7.11.24) (MAP kinase MSK7) (MAP kinase ERK1) Length = 387 Score = 60.5 bits (145), Expect = 3e-09 Identities = 41/141 (29%), Positives = 63/141 (44%) Frame = +3 Query: 132 VGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXXXXXXXXA 311 +G+G YG V A + T + VA+KK D++ LREI Sbjct: 61 IGKGAYGIVCSAHNSETNEHVAVKKIANAFDNKIDAKRTLREIKLLRHMDHENVVAIRDI 120 Query: 312 VEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKSFLYQLCKG 491 V + +Y+ +E +DTDL + + + + L + FLYQ+ +G Sbjct: 121 VPPPQREVFND------VYIAYELMDTDLHQIIRSNQA------LSEEHCQYFLYQILRG 168 Query: 492 IAHCHGHGVLHRDLKPQNLLV 554 + + H VLHRDLKP NLL+ Sbjct: 169 LKYIHSANVLHRDLKPSNLLL 189
>MAPK_PEA (Q06060) Mitogen-activated protein kinase homolog D5 (EC 2.7.11.24)| Length = 394 Score = 60.5 bits (145), Expect = 3e-09 Identities = 41/141 (29%), Positives = 63/141 (44%) Frame = +3 Query: 132 VGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXXXXXXXXA 311 +G+G YG V A + T + VA+KK D++ LREI Sbjct: 68 IGKGAYGIVCSAHNSETNEHVAVKKIANAFDNKIDAKRTLREIKLVRHMDHENVVAIRDI 127 Query: 312 VEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKSFLYQLCKG 491 V + +Y+ +E +DTDL + + + + L + FLYQ+ +G Sbjct: 128 VPPPQREVFND------VYIAYELMDTDLHQIIRSNQA------LSEEHCQYFLYQILRG 175 Query: 492 IAHCHGHGVLHRDLKPQNLLV 554 + + H VLHRDLKP NLL+ Sbjct: 176 LKYIHSANVLHRDLKPSNLLL 196
>ERKA_DROME (P40417) Mitogen-activated protein kinase ERK-A (EC 2.7.11.24)| (Extracellular-regulated kinase A) (Protein rolled) Length = 376 Score = 60.5 bits (145), Expect = 3e-09 Identities = 46/148 (31%), Positives = 64/148 (43%) Frame = +3 Query: 111 KYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXX 290 +Y KL +GEG YG V A D T Q VA+KK + + LREI Sbjct: 37 RYIKLAYIGEGAYGMVVSADDTLTNQRVAIKKIS-PFEHQTYCQRTLREITILTRFKHEN 95 Query: 291 XXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKSF 470 + + +Y+V ++TDL K + R L + F Sbjct: 96 IIDIRDILRVDSIDQMRD------VYIVQCLMETDLYKLLKTQR-------LSNDHICYF 142 Query: 471 LYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 LYQ+ +G+ + H VLHRDLKP NLL+ Sbjct: 143 LYQILRGLKYIHSANVLHRDLKPSNLLL 170
>MK15_MOUSE (Q80Y86) Mitogen-activated protein kinase 15 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 7) Length = 549 Score = 60.5 bits (145), Expect = 3e-09 Identities = 45/149 (30%), Positives = 66/149 (44%) Frame = +3 Query: 108 EKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXX 287 ++Y ++G+G YG V+KAMD+ TG+VVA+KK D+ REI Sbjct: 12 QRYLIKRRLGKGAYGIVWKAMDRRTGEVVAIKKIFDAFRDQIDAQRTFREIMLLKEFGGH 71 Query: 288 XXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKS 467 V +YLVFE +DTDL + ++G K + + Sbjct: 72 PNIIRLLDVIPAKNDRD--------IYLVFESMDTDLNAVI---QKGRLLKDIHKRCI-- 118 Query: 468 FLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 YQL + H V+HRD KP N+L+ Sbjct: 119 -FYQLLRATKFIHSGRVIHRDQKPANVLL 146
>MK15_RAT (Q9Z2A6) Mitogen-activated protein kinase 15 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 7) Length = 547 Score = 60.1 bits (144), Expect = 4e-09 Identities = 45/149 (30%), Positives = 63/149 (42%) Frame = +3 Query: 108 EKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXX 287 ++Y ++G+G YG V+KAMD+ TG+VVA+KK D+ REI Sbjct: 12 QRYLIKRRLGKGAYGIVWKAMDRRTGEVVAIKKIFDAFRDQTDAQRTFREIMLLREFGGH 71 Query: 288 XXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKS 467 V +YLVFE +DTDL + R L + Sbjct: 72 PNIIRLLDVIPAKNDRD--------IYLVFESMDTDLNAVIQKGRL------LEDIHKRC 117 Query: 468 FLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 YQL + H V+HRD KP N+L+ Sbjct: 118 IFYQLLRATKFIHSGRVIHRDQKPANVLL 146
>MK03_RAT (P21708) Mitogen-activated protein kinase 3 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 1) (ERK-1) (Insulin-stimulated MAP2 kinase) (MAP kinase 1) (MAPK 1) (p44-ERK1) (ERT2) (p44-MAPK) (Microtubule-associated protein 2 kinase) (MNK1) Length = 380 Score = 60.1 bits (144), Expect = 4e-09 Identities = 43/148 (29%), Positives = 65/148 (43%) Frame = +3 Query: 111 KYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXX 290 +Y +L+ +GEG YG V A D VA+KK + + LREI Sbjct: 42 RYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKIS-PFEHQTYCQRTLREIQILLGFRHEN 100 Query: 291 XXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKSF 470 + T +Y+V + ++TDL K + + + L + F Sbjct: 101 VIGIRDILRAPTLEAMRD------VYIVQDLMETDLYKLLKSQQ-------LSNDHICYF 147 Query: 471 LYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 LYQ+ +G+ + H VLHRDLKP NLL+ Sbjct: 148 LYQILRGLKYIHSANVLHRDLKPSNLLI 175
>MK03_MOUSE (Q63844) Mitogen-activated protein kinase 3 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 1) (ERK-1) (Insulin-stimulated MAP2 kinase) (MAP kinase 1) (MAPK 1) (p44-ERK1) (ERT2) (p44-MAPK) (Microtubule-associated protein 2 kinase) (MNK1) Length = 380 Score = 60.1 bits (144), Expect = 4e-09 Identities = 43/148 (29%), Positives = 65/148 (43%) Frame = +3 Query: 111 KYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXX 290 +Y +L+ +GEG YG V A D VA+KK + + LREI Sbjct: 42 RYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKIS-PFEHQTYCQRTLREIQILLRFRHEN 100 Query: 291 XXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKSF 470 + T +Y+V + ++TDL K + + + L + F Sbjct: 101 VIGIRDILRAPTLEAMRD------VYIVQDLMETDLYKLLKSQQ-------LSNDHICYF 147 Query: 471 LYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 LYQ+ +G+ + H VLHRDLKP NLL+ Sbjct: 148 LYQILRGLKYIHSANVLHRDLKPSNLLI 175
>SNF1_CANTR (O94168) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 619 Score = 60.1 bits (144), Expect = 4e-09 Identities = 44/152 (28%), Positives = 70/152 (46%), Gaps = 4/152 (2%) Frame = +3 Query: 111 KYEKLEKVGEGTYGKVYKAMDKATGQVVALK----KTRLEMDDEGIPPTALREIXXXXXX 278 +Y+ ++ +GEG++GKV A TGQ VALK KT + D +G REI Sbjct: 51 RYQIIKTLGEGSFGKVKLAQHVGTGQKVALKIINRKTLAKSDMQG---RVEREISYLRLL 107 Query: 279 XXXXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHV 458 ++ K + +V EF +L ++ +RG +P Sbjct: 108 RHPHIIKLYDVIKS-----------KDEIIMVIEFAGKELFDYI--VQRGK----MPEDE 150 Query: 459 VKSFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 + F Q+ + +CH H ++HRDLKP+NLL+ Sbjct: 151 ARRFFQQIIAAVEYCHRHKIVHRDLKPENLLL 182
>KSG5_ARATH (Q8VZD5) Shaggy-related protein kinase epsilon (EC 2.7.11.1)| (ASK-epsilon) Length = 410 Score = 59.3 bits (142), Expect = 7e-09 Identities = 46/144 (31%), Positives = 69/144 (47%), Gaps = 3/144 (2%) Frame = +3 Query: 132 VGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXXXXXXXXA 311 VG+G++G V++A TG+ VA+KK + + RE+ Sbjct: 80 VGQGSFGIVFQAKCLETGETVAIKKVLQDKRYKN------RELQTMRLLDHPNVVSLKHC 133 Query: 312 VEQTTKXXXXXXXXKPVLYL--VFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKSFLYQLC 485 TT+ K LYL V E++ + + Y R A + +P VK + YQ+C Sbjct: 134 FFSTTE--------KDELYLNLVLEYVPETVYRVSKHYSR--ANQRMPIIYVKLYTYQIC 183 Query: 486 KGIAHCHGH-GVLHRDLKPQNLLV 554 + +A+ HG GV HRD+KPQNLLV Sbjct: 184 RALAYIHGGVGVCHRDIKPQNLLV 207
>HOG1_CANGA (Q6FIU2) Mitogen-activated protein kinase HOG1 (EC 2.7.11.24) (MAP| kinase HOG1) Length = 447 Score = 59.3 bits (142), Expect = 7e-09 Identities = 42/148 (28%), Positives = 59/148 (39%) Frame = +3 Query: 111 KYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXX 290 +Y L VG G +G V A D T Q VA+KK + RE+ Sbjct: 22 RYSDLNPVGMGAFGLVCSATDTLTNQQVAIKKIMKPFATAVLAKRTYRELKLLKHLRH-- 79 Query: 291 XXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKSF 470 E +Y V E TDL + + +PL V+ F Sbjct: 80 --------ENLICLQDIFLSPLEDIYFVTELQGTDLHRLLQT-------RPLEKQFVQYF 124 Query: 471 LYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 YQ+ +G+ + H GV+HRDLKP N+L+ Sbjct: 125 HYQILRGLKYVHSAGVVHRDLKPSNILI 152
>MK14B_DROME (O61443) Mitogen-activated protein kinase 14B (EC 2.7.11.24) (MAP| kinase p38b) (D-p38b) Length = 365 Score = 59.3 bits (142), Expect = 7e-09 Identities = 39/149 (26%), Positives = 61/149 (40%) Frame = +3 Query: 108 EKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXX 287 E Y+ L+ VG+G YG+V KA+ + T VA+KK RE+ Sbjct: 22 ETYQNLQPVGQGAYGQVCKAVVRGTSTKVAIKKLARPFQSAVHAKRTYRELRLLKHMDHE 81 Query: 288 XXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKS 467 + +Y+V +D DL + + L V+ Sbjct: 82 NVIGLLDVFHPGQPADSLDQFQQ--VYMVTHLMDADLNNIIRTQK-------LSDDHVQF 132 Query: 468 FLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 +YQ+ +G+ + H GV+HRDLKP N+ V Sbjct: 133 LVYQILRGLKYIHSAGVIHRDLKPSNIAV 161
>KSG10_ARATH (Q39019) Shaggy-related protein kinase kappa (EC 2.7.11.1)| (ASK-kappa) (AtK-1) Length = 421 Score = 59.3 bits (142), Expect = 7e-09 Identities = 43/142 (30%), Positives = 68/142 (47%), Gaps = 1/142 (0%) Frame = +3 Query: 132 VGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXXXXXXXXA 311 VG G++G V++A + TG+VVA+KK + D+ L+ + A Sbjct: 89 VGTGSFGMVFQAKCRETGEVVAIKKV---LQDKRYKNRELQIMQMLDHPN---------A 136 Query: 312 VEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKSFLYQLCKG 491 V + L LV EF+ + + +Y R + +P VK + YQ+C+ Sbjct: 137 VALKHSFFSRTDNEEVYLNLVLEFVPETVNRVARSYSR--TNQLMPLIYVKLYTYQICRA 194 Query: 492 IAHCHGH-GVLHRDLKPQNLLV 554 +A+ H G+ HRD+KPQNLLV Sbjct: 195 LAYIHNSFGLCHRDIKPQNLLV 216
>STK36_PONPY (Q5RAJ5) Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused| homolog) Length = 1315 Score = 58.9 bits (141), Expect = 9e-09 Identities = 43/150 (28%), Positives = 68/150 (45%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 MEKY LE +GEG++G+VYK K + QVVALK E REI Sbjct: 1 MEKYHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLRH 60 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 + E + + +V ++ + +L + ++ + LP V+ Sbjct: 61 PNIVHMLDSFETDKE-----------VVVVTDYAEGELLQILEDDGK------LPEDQVQ 103 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 + QL + + H H +LHRD+KPQN+L+ Sbjct: 104 AIAAQLVSALYYLHSHRILHRDMKPQNILL 133
>NUAK1_HUMAN (O60285) NUAK family, SNF1-like kinase 1 (EC 2.7.11.1)| (AMPK-related protein kinase 5) Length = 661 Score = 58.9 bits (141), Expect = 9e-09 Identities = 42/150 (28%), Positives = 69/150 (46%), Gaps = 2/150 (1%) Frame = +3 Query: 111 KYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLE-MDDEGIPPTALREIXXXXXXXXX 287 +YE E +G+GTYGKV +A ++ +G+VVA+K R + + DE REI Sbjct: 54 RYELQETLGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDEQDMVHIRREIEIMSSLNHP 113 Query: 288 XXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDT-DLKKFVDAYRRGPAPKPLPTHVVK 464 E K + ++ E+ +L ++ RR L + Sbjct: 114 HIISIYEVFENKDK-----------IVIIMEYASKGELYDYISERRR------LSERETR 156 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 F Q+ + +CH +GV+HRDLK +N+L+ Sbjct: 157 HFFRQIVSAVHYCHKNGVVHRDLKLENILL 186
>KSG4_ARATH (Q9FVS6) Shaggy-related protein kinase delta (EC 2.7.11.1)| (ASK-delta) Length = 420 Score = 58.5 bits (140), Expect = 1e-08 Identities = 43/142 (30%), Positives = 69/142 (48%), Gaps = 1/142 (0%) Frame = +3 Query: 132 VGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXXXXXXXXA 311 VG G++G V++A + TG+VVA+KK + + RE+ + Sbjct: 88 VGTGSFGMVFQAKCRETGEVVAIKKVLQDKRYKN------RELQIMQMLDHPNVVCLKHS 141 Query: 312 VEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKSFLYQLCKG 491 T+ + L LV EF+ + + +Y R + +P VK + YQ+C+G Sbjct: 142 FYSRTENE------EVYLNLVLEFVPETVNRTARSYSR--MNQLMPLIYVKLYTYQICRG 193 Query: 492 IAHCHGH-GVLHRDLKPQNLLV 554 +A+ H G+ HRD+KPQNLLV Sbjct: 194 LAYLHNCCGLCHRDIKPQNLLV 215
>NUAK1_MOUSE (Q641K5) NUAK family, SNF1-like kinase 1 (EC 2.7.11.1)| Length = 658 Score = 58.2 bits (139), Expect = 2e-08 Identities = 42/150 (28%), Positives = 69/150 (46%), Gaps = 2/150 (1%) Frame = +3 Query: 111 KYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLE-MDDEGIPPTALREIXXXXXXXXX 287 +YE E +G+GTYGKV +A ++ +G+VVA+K R + + DE REI Sbjct: 55 RYELQETLGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDELDMVHIRREIEIMSSLNHP 114 Query: 288 XXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDT-DLKKFVDAYRRGPAPKPLPTHVVK 464 E K + ++ E+ +L ++ RR L + Sbjct: 115 HIISIYEVFENKDK-----------IVIIMEYASKGELYDYISERRR------LSERETR 157 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 F Q+ + +CH +GV+HRDLK +N+L+ Sbjct: 158 HFFRQIVSAVHYCHKNGVVHRDLKLENILL 187
>KSS1_YEAST (P14681) Mitogen-activated protein kinase KSS1 (EC 2.7.11.24) (MAP| kinase KSS1) (Kinase suppressor of SST2) Length = 368 Score = 58.2 bits (139), Expect = 2e-08 Identities = 42/148 (28%), Positives = 68/148 (45%) Frame = +3 Query: 111 KYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXX 290 +Y+ ++ +GEG YG V A+ K +G VA+KK + + +REI Sbjct: 12 QYKLVDLIGEGAYGTVCSAIHKPSGIKVAIKKIQ-PFSKKLFVTRTIREIKLLRYFHEHE 70 Query: 291 XXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKSF 470 + K +YLV E ++TDL+K ++ G + L V+ F Sbjct: 71 NI-----ISILDKVRPVSIDKLNAVYLVEELMETDLQKVINNQNSGFST--LSDDHVQYF 123 Query: 471 LYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 YQ+ + + H V+HRD+KP NLL+ Sbjct: 124 TYQILRALKSIHSAQVIHRDIKPSNLLL 151
>MK01_HUMAN (P28482) Mitogen-activated protein kinase 1 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 2) (ERK-2) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2) (p42-MAPK) (ERT1) Length = 359 Score = 57.8 bits (138), Expect = 2e-08 Identities = 43/148 (29%), Positives = 61/148 (41%) Frame = +3 Query: 111 KYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXX 290 +Y L +GEG YG V A D VA+KK + + LREI Sbjct: 23 RYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKIS-PFEHQTYCQRTLREIKILLRFRHEN 81 Query: 291 XXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKSF 470 + T +Y+V + ++TDL K + L + F Sbjct: 82 IIGINDIIRAPTIEQMKD------VYIVQDLMETDLYKLLKTQH-------LSNDHICYF 128 Query: 471 LYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 LYQ+ +G+ + H VLHRDLKP NLL+ Sbjct: 129 LYQILRGLKYIHSANVLHRDLKPSNLLL 156
>MK01_BOVIN (P46196) Mitogen-activated protein kinase 1 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 2) (ERK-2) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2) (p42-MAPK) (ERT1) Length = 359 Score = 57.8 bits (138), Expect = 2e-08 Identities = 43/148 (29%), Positives = 61/148 (41%) Frame = +3 Query: 111 KYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXX 290 +Y L +GEG YG V A D VA+KK + + LREI Sbjct: 23 RYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKIS-PFEHQTYCQRTLREIKILLRFRHEN 81 Query: 291 XXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKSF 470 + T +Y+V + ++TDL K + L + F Sbjct: 82 IIGINDIIRAPTIEQMKD------VYIVQDLMETDLYKLLKTQH-------LSNDHICYF 128 Query: 471 LYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 LYQ+ +G+ + H VLHRDLKP NLL+ Sbjct: 129 LYQILRGLKYIHSANVLHRDLKPSNLLL 156
>JNK1_ANCCA (Q9U6D2) Stress-activated protein kinase JNK-1 (EC 2.7.11.24)| Length = 376 Score = 57.4 bits (137), Expect = 3e-08 Identities = 41/150 (27%), Positives = 60/150 (40%) Frame = +3 Query: 105 MEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXX 284 +++YE L +G G G V A D T + VA+KK + A RE Sbjct: 23 LKRYENLRLIGSGAQGIVCAATDMVTNKPVAIKKLSRPFQNVTHAKRAYREFILMNLVNH 82 Query: 285 XXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVK 464 A + LY+V E +D +L + + L + Sbjct: 83 KNIIGLLNAFSPQREVEEFND-----LYIVMELMDANLCQVIQM--------DLDHERLS 129 Query: 465 SFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 LYQ+ GI H H G++HRDLKP N++V Sbjct: 130 YLLYQMLCGIKHLHSAGIIHRDLKPSNIVV 159
>CDC15_YEAST (P27636) Cell division control protein 15 (EC 2.7.11.1)| Length = 974 Score = 57.4 bits (137), Expect = 3e-08 Identities = 40/149 (26%), Positives = 71/149 (47%), Gaps = 1/149 (0%) Frame = +3 Query: 111 KYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXX 290 +Y + +G G+YG VYKA++K T QVVA+K+ E D+E + EI Sbjct: 24 QYHLKQVIGRGSYGVVYKAINKHTDQVVAIKEVVYENDEE--LNDIMAEISLLKNLNHNN 81 Query: 291 XXXXXXAVEQTTKXXXXXXXXKPVLYLVFEF-LDTDLKKFVDAYRRGPAPKPLPTHVVKS 467 + ++ + LY++ E+ + L++ + G + T+V ++ Sbjct: 82 IVKYHGFIRKSYE-----------LYILLEYCANGSLRRLISRSSTGLSENESKTYVTQT 130 Query: 468 FLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 L G+ + HG GV+HRD+K N+L+ Sbjct: 131 LL-----GLKYLHGEGVIHRDIKAANILL 154
>STK4_HUMAN (Q13043) Serine/threonine-protein kinase 4 (EC 2.7.11.1)| (STE20-like kinase MST1) (MST-1) (Mammalian STE20-like protein kinase 1) (Serine/threonine-protein kinase Krs-2) Length = 487 Score = 57.4 bits (137), Expect = 3e-08 Identities = 42/149 (28%), Positives = 68/149 (45%) Frame = +3 Query: 108 EKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXX 287 E ++ LEK+GEG+YG VYKA+ K TGQ+VA+K+ +E D + I ++EI Sbjct: 28 EVFDVLEKLGEGSYGSVYKAIHKETGQIVAIKQVPVESDLQEI----IKEISIMQQCDSP 83 Query: 288 XXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKS 467 + + T L++V E+ + R K L + + Sbjct: 84 HVVKYYGSYFKNTD-----------LWIVMEYCGAGSVSDIIRLRN----KTLTEDEIAT 128 Query: 468 FLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 L KG+ + H +HRD+K N+L+ Sbjct: 129 ILQSTLKGLEYLHFMRKIHRDIKAGNILL 157
>MK14B_CYPCA (Q9I958) Mitogen-activated protein kinase 14b (EC 2.7.11.24)| (Mitogen-activated protein kinase p38b) (MAP kinase p38b) (cp38b) Length = 361 Score = 57.4 bits (137), Expect = 3e-08 Identities = 41/149 (27%), Positives = 58/149 (38%) Frame = +3 Query: 108 EKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXX 287 E+Y+ L VG G YG V A+D +G VA+KK RE+ Sbjct: 23 ERYQNLSPVGSGAYGSVCSALDTKSGLRVAVKKLSRPFQSMIHAKRTYRELRLLKHMKHE 82 Query: 288 XXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKS 467 A T +YLV + DL V + L V+ Sbjct: 83 NVIGLLDAFSPATCLAGFND-----VYLVTHLMGADLNNIVKCQK-------LTDDHVQF 130 Query: 468 FLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 +YQ+ +G+ + H ++HRDLKP NL V Sbjct: 131 LIYQILRGLKYIHSADIIHRDLKPSNLAV 159
>MK01_RAT (P63086) Mitogen-activated protein kinase 1 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 2) (ERK-2) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2) (p42-MAPK) (ERT1) Length = 357 Score = 57.4 bits (137), Expect = 3e-08 Identities = 43/148 (29%), Positives = 61/148 (41%) Frame = +3 Query: 111 KYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXX 290 +Y L +GEG YG V A D VA+KK + + LREI Sbjct: 21 RYTNLSYIGEGAYGMVCSAYDNLNKVRVAIKKIS-PFEHQTYCQRTLREIKILLRFRHEN 79 Query: 291 XXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKSF 470 + T +Y+V + ++TDL K + L + F Sbjct: 80 IIGINDIIRAPTIEQMKD------VYIVQDLMETDLYKLLKTQH-------LSNDHICYF 126 Query: 471 LYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 LYQ+ +G+ + H VLHRDLKP NLL+ Sbjct: 127 LYQILRGLKYIHSANVLHRDLKPSNLLL 154
>MK01_MOUSE (P63085) Mitogen-activated protein kinase 1 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 2) (ERK-2) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2) (p42-MAPK) (ERT1) Length = 357 Score = 57.4 bits (137), Expect = 3e-08 Identities = 43/148 (29%), Positives = 61/148 (41%) Frame = +3 Query: 111 KYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXX 290 +Y L +GEG YG V A D VA+KK + + LREI Sbjct: 21 RYTNLSYIGEGAYGMVCSAYDNLNKVRVAIKKIS-PFEHQTYCQRTLREIKILLRFRHEN 79 Query: 291 XXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKSF 470 + T +Y+V + ++TDL K + L + F Sbjct: 80 IIGINDIIRAPTIEQMKD------VYIVQDLMETDLYKLLKTQH-------LSNDHICYF 126 Query: 471 LYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 LYQ+ +G+ + H VLHRDLKP NLL+ Sbjct: 127 LYQILRGLKYIHSANVLHRDLKPSNLLL 154
>SPK1_SCHPO (P27638) Mitogen-activated protein kinase spk1 (EC 2.7.11.24) (MAP| kinase spk1) (MAPK) Length = 372 Score = 57.0 bits (136), Expect = 4e-08 Identities = 42/149 (28%), Positives = 66/149 (44%) Frame = +3 Query: 108 EKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXX 287 E+YE + +G+G YG V A+ K +G VA+KK + LREI Sbjct: 37 EEYEMINLIGQGAYGVVCAALHKPSGLKVAVKKIH-PFNHPVFCLRTLREIKLLRHFRHE 95 Query: 288 XXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKS 467 + + +Y+V E ++TDL + + + +PL + Sbjct: 96 NIISILDILPPPSYQELED------VYIVQELMETDLYRVIRS-------QPLSDDHCQY 142 Query: 468 FLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 F YQ+ + + H GV+HRDLKP NLL+ Sbjct: 143 FTYQILRALKAMHSAGVVHRDLKPSNLLL 171
>MSK2_MEDSA (P51138) Glycogen synthase kinase-3 homolog MsK-2 (EC 2.7.11.1)| Length = 411 Score = 57.0 bits (136), Expect = 4e-08 Identities = 44/144 (30%), Positives = 68/144 (47%), Gaps = 3/144 (2%) Frame = +3 Query: 132 VGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXXXXXXXXA 311 VG+G++G V++A TG+ VA+KK + D+ L+ + Sbjct: 80 VGQGSFGVVFQAKCLETGETVAIKKV---LQDKRYKNRELQTMRLLDHPNVV-------- 128 Query: 312 VEQTTKXXXXXXXXKPVLYL--VFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKSFLYQLC 485 T K K LYL V EF+ + + + Y + + +P VK + YQ+C Sbjct: 129 ---TLKHCFFSTTEKDELYLNLVLEFVPETVHRVIRHYSK--MNQRMPLIYVKLYSYQIC 183 Query: 486 KGIAHCHGH-GVLHRDLKPQNLLV 554 + +A+ H GV HRD+KPQNLLV Sbjct: 184 RSLAYIHNCVGVSHRDIKPQNLLV 207
>PKN1_THETN (Q8R9T6) Probable serine/threonine-protein kinase Sps1 (EC| 2.7.11.1) Length = 625 Score = 57.0 bits (136), Expect = 4e-08 Identities = 41/149 (27%), Positives = 62/149 (41%), Gaps = 1/149 (0%) Frame = +3 Query: 111 KYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMD-DEGIPPTALREIXXXXXXXXX 287 +YE LEK+GEG KVYKA ++VA+K R E DE RE Sbjct: 9 RYEILEKIGEGGMAKVYKAKCHLLNRIVAIKILRPEFAADENFVKKFKRESQAAASLSHP 68 Query: 288 XXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKS 467 ++ + Y+V E++ K + GP + Sbjct: 69 NIVGIYDVGQEGD-----------IYYIVMEYVKGRTLKELIRENGGPLEVKRAVEIAS- 116 Query: 468 FLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 Q+C+ + H H + ++HRD+KPQN+LV Sbjct: 117 ---QVCRALDHAHKNKIIHRDIKPQNILV 142
>YPC2_CAEEL (Q11179) Putative serine/threonine-protein kinase C05D10.2 in| chromosome III (EC 2.7.11.24) Length = 470 Score = 56.6 bits (135), Expect = 5e-08 Identities = 41/149 (27%), Positives = 66/149 (44%) Frame = +3 Query: 108 EKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXX 287 EK++ +++G+G YG V+KA DK + + VALKK + RE+ Sbjct: 11 EKFDLQKRLGKGAYGIVWKAYDKRSRETVALKKIFDAFRNPTDSQRTFREVMFLQEFGKH 70 Query: 288 XXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKS 467 + + +YL FEF++ DL + ++G K + + Sbjct: 71 PNVIKLYNIFRADNDRD--------IYLAFEFMEADLHNVI---KKGSILKDVHKQYI-- 117 Query: 468 FLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 + QL + I H VLHRDLKP N+L+ Sbjct: 118 -MCQLFRAIRFLHSGNVLHRDLKPSNVLL 145
>GSK3B_RAT (P18266) Glycogen synthase kinase-3 beta (EC 2.7.11.26) (GSK-3| beta) (Factor A) (FA) Length = 420 Score = 56.6 bits (135), Expect = 5e-08 Identities = 38/147 (25%), Positives = 67/147 (45%) Frame = +3 Query: 114 YEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXXX 293 Y + +G G++G VY+A +G++VA+KK + + +R++ Sbjct: 56 YTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYF 115 Query: 294 XXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKSFL 473 + L LV +++ + + Y R A + LP VK ++ Sbjct: 116 FYSSGEKKDEV-----------YLNLVLDYVPETVYRVARHYSR--AKQTLPVIYVKLYM 162 Query: 474 YQLCKGIAHCHGHGVLHRDLKPQNLLV 554 YQL + +A+ H G+ HRD+KPQNLL+ Sbjct: 163 YQLFRSLAYIHSFGICHRDIKPQNLLL 189
>GSK3B_MOUSE (Q9WV60) Glycogen synthase kinase-3 beta (EC 2.7.11.26) (GSK-3| beta) Length = 420 Score = 56.6 bits (135), Expect = 5e-08 Identities = 38/147 (25%), Positives = 67/147 (45%) Frame = +3 Query: 114 YEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXXX 293 Y + +G G++G VY+A +G++VA+KK + + +R++ Sbjct: 56 YTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYF 115 Query: 294 XXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKSFL 473 + L LV +++ + + Y R A + LP VK ++ Sbjct: 116 FYSSGEKKDEV-----------YLNLVLDYVPETVYRVARHYSR--AKQTLPVIYVKLYM 162 Query: 474 YQLCKGIAHCHGHGVLHRDLKPQNLLV 554 YQL + +A+ H G+ HRD+KPQNLL+ Sbjct: 163 YQLFRSLAYIHSFGICHRDIKPQNLLL 189
>GSK3B_HUMAN (P49841) Glycogen synthase kinase-3 beta (EC 2.7.11.26) (GSK-3| beta) Length = 420 Score = 56.6 bits (135), Expect = 5e-08 Identities = 38/147 (25%), Positives = 67/147 (45%) Frame = +3 Query: 114 YEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXXX 293 Y + +G G++G VY+A +G++VA+KK + + +R++ Sbjct: 56 YTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYF 115 Query: 294 XXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKSFL 473 + L LV +++ + + Y R A + LP VK ++ Sbjct: 116 FYSSGEKKDEV-----------YLNLVLDYVPETVYRVARHYSR--AKQTLPVIYVKLYM 162 Query: 474 YQLCKGIAHCHGHGVLHRDLKPQNLLV 554 YQL + +A+ H G+ HRD+KPQNLL+ Sbjct: 163 YQLFRSLAYIHSFGICHRDIKPQNLLL 189
>GSK3A_HUMAN (P49840) Glycogen synthase kinase-3 alpha (EC 2.7.11.26) (GSK-3| alpha) Length = 483 Score = 56.2 bits (134), Expect = 6e-08 Identities = 40/149 (26%), Positives = 69/149 (46%), Gaps = 2/149 (1%) Frame = +3 Query: 114 YEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXXX 293 Y ++ +G G++G VY+A T ++VA+KK + + +R++ Sbjct: 119 YTDIKVIGNGSFGVVYQARLAETRELVAIKKVLQDKRFKNRELQIMRKLDHCN------- 171 Query: 294 XXXXXAVEQTTKXXXXXXXXKPVLYL--VFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKS 467 + + K LYL V E++ + + + + A +P VK Sbjct: 172 ------IVRLRYFFYSSGEKKDELYLNLVLEYVPETVYRVARHFTK--AKLTIPILYVKV 223 Query: 468 FLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 ++YQL + +A+ H GV HRD+KPQNLLV Sbjct: 224 YMYQLFRSLAYIHSQGVCHRDIKPQNLLV 252
>MK06_HUMAN (Q16659) Mitogen-activated protein kinase 6 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 3) (ERK-3) (MAP kinase isoform p97) (p97-MAPK) Length = 721 Score = 56.2 bits (134), Expect = 6e-08 Identities = 45/152 (29%), Positives = 67/152 (44%), Gaps = 4/152 (2%) Frame = +3 Query: 111 KYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXX 290 +Y L+ +G G G V+ A+D + VA+KK + + D ALREI Sbjct: 19 RYMDLKPLGCGGNGLVFSAVDNDCDKRVAIKK--IVLTDPQSVKHALREIKIIRRLDHDN 76 Query: 291 XXXXXXAV----EQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHV 458 + Q T V Y+V E+++TDL ++ PL Sbjct: 77 IVKVFEILGPSGSQLTDDVGSLTELNSV-YIVQEYMETDLANVLEQ-------GPLLEEH 128 Query: 459 VKSFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 + F+YQL +G+ + H VLHRDLKP NL + Sbjct: 129 ARLFMYQLLRGLKYIHSANVLHRDLKPANLFI 160
>MSK3_MEDSA (P51139) Glycogen synthase kinase-3 homolog MsK-3 (EC 2.7.11.1)| Length = 411 Score = 56.2 bits (134), Expect = 6e-08 Identities = 43/144 (29%), Positives = 67/144 (46%), Gaps = 3/144 (2%) Frame = +3 Query: 132 VGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXXXXXXXXA 311 VG G++G V++A TG+ VA+KK + + RE+ Sbjct: 80 VGHGSFGVVFQAKCLETGETVAIKKVLQDKRYKN------RELQTMRLLDHPNVVSLKHC 133 Query: 312 VEQTTKXXXXXXXXKPVLYL--VFEFLDTDLKKFVDAYRRGPAPKPLPTHVVKSFLYQLC 485 TT+ K LYL V E++ + + + Y + + +P VK + YQ+C Sbjct: 134 FFSTTE--------KDELYLNLVLEYVPETVSRVIRHYNK--MNQRMPMIYVKLYSYQIC 183 Query: 486 KGIAHCHGH-GVLHRDLKPQNLLV 554 + +A+ H GV HRD+KPQNLLV Sbjct: 184 RALAYIHNSIGVCHRDIKPQNLLV 207
>JNK_SUBDO (Q966Y3) Stress-activated protein kinase JNK (EC 2.7.11.24)| Length = 361 Score = 56.2 bits (134), Expect = 6e-08 Identities = 39/152 (25%), Positives = 59/152 (38%) Frame = +3 Query: 99 SAMEKYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXX 278 + ++Y L +G G G V A D T + +A+KK +E A RE+ Sbjct: 17 TVQKRYTNLTNIGSGAQGVVCSAFDTVTQEKIAIKKLVKPFQNETYAKRAFRELRLMKMV 76 Query: 279 XXXXXXXXXXAVEQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHV 458 +Y+V E +D +L + + L Sbjct: 77 DHKNIIGLKNLFTPAKSLDDFQD-----VYIVMELMDANLCRVIGI--------ELDHDR 123 Query: 459 VKSFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 + LYQL GI H H G++HRDLKP N++V Sbjct: 124 MSYLLYQLLCGIKHLHSAGIIHRDLKPSNIVV 155
>MK06_RAT (P27704) Mitogen-activated protein kinase 6 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 3) (ERK-3) (p55-MAPK) Length = 720 Score = 56.2 bits (134), Expect = 6e-08 Identities = 45/152 (29%), Positives = 67/152 (44%), Gaps = 4/152 (2%) Frame = +3 Query: 111 KYEKLEKVGEGTYGKVYKAMDKATGQVVALKKTRLEMDDEGIPPTALREIXXXXXXXXXX 290 +Y L+ +G G G V+ A+D + VA+KK + + D ALREI Sbjct: 19 RYMDLKPLGCGGNGLVFSAVDNDCDKRVAIKK--IVLTDPQSVKHALREIKIIRRLDHDN 76 Query: 291 XXXXXXAV----EQTTKXXXXXXXXKPVLYLVFEFLDTDLKKFVDAYRRGPAPKPLPTHV 458 + Q T V Y+V E+++TDL ++ PL Sbjct: 77 IVKVFEILGPSGSQLTDDVGSLTELNSV-YIVQEYMETDLANVLEQ-------GPLLEEH 128 Query: 459 VKSFLYQLCKGIAHCHGHGVLHRDLKPQNLLV 554 + F+YQL +G+ + H VLHRDLKP NL + Sbjct: 129 ARLFMYQLLRGLKYIHSANVLHRDLKPANLFI 160 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 52,050,706 Number of Sequences: 219361 Number of extensions: 806814 Number of successful extensions: 6589 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 5058 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 6125 length of database: 80,573,946 effective HSP length: 105 effective length of database: 57,541,041 effective search space used: 4545742239 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
