ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
menu 
| Clone Name | bart23e11 |
|---|---|
| Clone Library Name | barley_pub |
>CSK2A_MAIZE (P28523) Casein kinase II subunit alpha (EC 2.7.11.1) (CK II)| (CK2-alpha) Length = 332 Score = 261 bits (668), Expect = 8e-70 Identities = 127/151 (84%), Positives = 129/151 (85%) Frame = +3 Query: 141 MSKARVYADVNVVRPKEYWDYEALAVQWGEQDDYEVVRKVGRGKYSEVFEGINVNNNEXX 320 MSKARVYADVNV+RPKEYWDYEAL VQWGEQDDYEVVRKVGRGKYSEVFEGINVNNNE Sbjct: 1 MSKARVYADVNVLRPKEYWDYEALTVQWGEQDDYEVVRKVGRGKYSEVFEGINVNNNEKC 60 Query: 321 XXXXXXXXXXXXXXXXXXXLQNLCGGPNIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLY 500 LQNLCGGPNIVKLLDIVRDQHSKTPSLIFEY+NNTDFKVLY Sbjct: 61 IIKILKPVKKKKIKREIKILQNLCGGPNIVKLLDIVRDQHSKTPSLIFEYVNNTDFKVLY 120 Query: 501 PTLTDYDIRYYIYELLKALDYCHSQGIMHRD 593 PTLTDYDIRYYIYELLKALDYCHSQGIMHRD Sbjct: 121 PTLTDYDIRYYIYELLKALDYCHSQGIMHRD 151
>CSK22_ARATH (Q08466) Casein kinase II subunit alpha-2 (EC 2.7.11.1) (CK II)| Length = 333 Score = 253 bits (645), Expect = 4e-67 Identities = 120/151 (79%), Positives = 128/151 (84%) Frame = +3 Query: 141 MSKARVYADVNVVRPKEYWDYEALAVQWGEQDDYEVVRKVGRGKYSEVFEGINVNNNEXX 320 MSKARVY DVNV+RPK+YWDYE+L VQWGEQDDYEVVRKVGRGKYSEVFEGIN+NNNE Sbjct: 1 MSKARVYTDVNVIRPKDYWDYESLNVQWGEQDDYEVVRKVGRGKYSEVFEGINMNNNEKC 60 Query: 321 XXXXXXXXXXXXXXXXXXXLQNLCGGPNIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLY 500 LQNLCGGPNIVKLLD+VRDQHSKTPSLIFEY+N+TDFKVLY Sbjct: 61 IIKILKPVKKKKIRREIKILQNLCGGPNIVKLLDVVRDQHSKTPSLIFEYVNSTDFKVLY 120 Query: 501 PTLTDYDIRYYIYELLKALDYCHSQGIMHRD 593 PTLTDYDIRYYIYELLKALD+CHSQGIMHRD Sbjct: 121 PTLTDYDIRYYIYELLKALDFCHSQGIMHRD 151
>CSK21_ARATH (Q08467) Casein kinase II subunit alpha-1 (EC 2.7.11.1) (CK II)| Length = 333 Score = 248 bits (634), Expect = 7e-66 Identities = 118/151 (78%), Positives = 127/151 (84%) Frame = +3 Query: 141 MSKARVYADVNVVRPKEYWDYEALAVQWGEQDDYEVVRKVGRGKYSEVFEGINVNNNEXX 320 MSKARVY +VNV+RPK+YWDYE+L VQWGEQDDYEVVRKVGRGKYSEVFEGINVN+ E Sbjct: 1 MSKARVYTEVNVIRPKDYWDYESLIVQWGEQDDYEVVRKVGRGKYSEVFEGINVNSKEKC 60 Query: 321 XXXXXXXXXXXXXXXXXXXLQNLCGGPNIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLY 500 LQNLCGGPNIVKLLD+VRDQHSKTPSLIFEY+N+TDFKVLY Sbjct: 61 IIKILKPVKKKKIRREIKILQNLCGGPNIVKLLDVVRDQHSKTPSLIFEYVNSTDFKVLY 120 Query: 501 PTLTDYDIRYYIYELLKALDYCHSQGIMHRD 593 PTLTDYDIRYYIYELLKALD+CHSQGIMHRD Sbjct: 121 PTLTDYDIRYYIYELLKALDFCHSQGIMHRD 151
>CSK23_ARATH (O64817) Probable casein kinase II subunit alpha (EC 2.7.11.1) (CK| II) Length = 333 Score = 243 bits (619), Expect = 4e-64 Identities = 116/151 (76%), Positives = 123/151 (81%) Frame = +3 Query: 141 MSKARVYADVNVVRPKEYWDYEALAVQWGEQDDYEVVRKVGRGKYSEVFEGINVNNNEXX 320 MSKARVY DVNVVRPKEYWDYE+L VQWG QDDYEVVRKVGRGKYSEVFEG NVN NE Sbjct: 1 MSKARVYTDVNVVRPKEYWDYESLVVQWGHQDDYEVVRKVGRGKYSEVFEGKNVNTNERC 60 Query: 321 XXXXXXXXXXXXXXXXXXXLQNLCGGPNIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLY 500 LQNLCGGPNIVKL DIVRD+HSKTPSL+FE++N+ DFKVLY Sbjct: 61 VIKILKPVKKKKIKREIKILQNLCGGPNIVKLYDIVRDEHSKTPSLVFEFVNSVDFKVLY 120 Query: 501 PTLTDYDIRYYIYELLKALDYCHSQGIMHRD 593 PTLTDYDIRYYIYELLKALD+CHSQGIMHRD Sbjct: 121 PTLTDYDIRYYIYELLKALDFCHSQGIMHRD 151
>CSK2A_DICDI (Q02720) Casein kinase II subunit alpha (EC 2.7.11.1) (CK II alpha| subunit) Length = 337 Score = 210 bits (534), Expect = 3e-54 Identities = 98/150 (65%), Positives = 113/150 (75%) Frame = +3 Query: 144 SKARVYADVNVVRPKEYWDYEALAVQWGEQDDYEVVRKVGRGKYSEVFEGINVNNNEXXX 323 +KAR+Y DVN+ +PKEYW+YEAL V+W QDDYE++RK+GRGKYSEVFEG N+ NNE Sbjct: 15 NKARIYCDVNLHKPKEYWNYEALNVKWETQDDYEIIRKIGRGKYSEVFEGANIKNNEKCV 74 Query: 324 XXXXXXXXXXXXXXXXXXLQNLCGGPNIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYP 503 LQNLCGGPNI+ L D+VRD SKTPSLIFEYINNTDFK L P Sbjct: 75 IKVLKPVKKKKIKREIKILQNLCGGPNIITLYDVVRDPQSKTPSLIFEYINNTDFKHLSP 134 Query: 504 TLTDYDIRYYIYELLKALDYCHSQGIMHRD 593 TLTD+D+RYYI ELL ALD+CHS GIMHRD Sbjct: 135 TLTDFDVRYYIRELLHALDFCHSNGIMHRD 164
>CSK21_RAT (P19139) Casein kinase II subunit alpha (EC 2.7.11.1) (CK II)| Length = 391 Score = 204 bits (520), Expect = 1e-52 Identities = 95/155 (61%), Positives = 114/155 (73%) Frame = +3 Query: 129 SSSAMSKARVYADVNVVRPKEYWDYEALAVQWGEQDDYEVVRKVGRGKYSEVFEGINVNN 308 S S+ARVY DVN RP+EYWDYE+ V+WG QDDY++VRK+GRGKYSEVFE IN+ N Sbjct: 2 SGPVPSRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITN 61 Query: 309 NEXXXXXXXXXXXXXXXXXXXXXLQNLCGGPNIVKLLDIVRDQHSKTPSLIFEYINNTDF 488 NE L+NL GGPNI+ L DIV+D S+TP+L+FE++NNTDF Sbjct: 62 NEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDF 121 Query: 489 KVLYPTLTDYDIRYYIYELLKALDYCHSQGIMHRD 593 K LY TLTDYDIR+Y+YE+LKALDYCHS GIMHRD Sbjct: 122 KQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRD 156
>CSK21_MOUSE (Q60737) Casein kinase II subunit alpha (EC 2.7.11.1) (CK II)| Length = 391 Score = 204 bits (520), Expect = 1e-52 Identities = 95/155 (61%), Positives = 114/155 (73%) Frame = +3 Query: 129 SSSAMSKARVYADVNVVRPKEYWDYEALAVQWGEQDDYEVVRKVGRGKYSEVFEGINVNN 308 S S+ARVY DVN RP+EYWDYE+ V+WG QDDY++VRK+GRGKYSEVFE IN+ N Sbjct: 2 SGPVPSRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITN 61 Query: 309 NEXXXXXXXXXXXXXXXXXXXXXLQNLCGGPNIVKLLDIVRDQHSKTPSLIFEYINNTDF 488 NE L+NL GGPNI+ L DIV+D S+TP+L+FE++NNTDF Sbjct: 62 NEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDF 121 Query: 489 KVLYPTLTDYDIRYYIYELLKALDYCHSQGIMHRD 593 K LY TLTDYDIR+Y+YE+LKALDYCHS GIMHRD Sbjct: 122 KQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRD 156
>CSK21_HUMAN (P68400) Casein kinase II subunit alpha (EC 2.7.11.1) (CK II)| Length = 391 Score = 204 bits (520), Expect = 1e-52 Identities = 95/155 (61%), Positives = 114/155 (73%) Frame = +3 Query: 129 SSSAMSKARVYADVNVVRPKEYWDYEALAVQWGEQDDYEVVRKVGRGKYSEVFEGINVNN 308 S S+ARVY DVN RP+EYWDYE+ V+WG QDDY++VRK+GRGKYSEVFE IN+ N Sbjct: 2 SGPVPSRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITN 61 Query: 309 NEXXXXXXXXXXXXXXXXXXXXXLQNLCGGPNIVKLLDIVRDQHSKTPSLIFEYINNTDF 488 NE L+NL GGPNI+ L DIV+D S+TP+L+FE++NNTDF Sbjct: 62 NEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDF 121 Query: 489 KVLYPTLTDYDIRYYIYELLKALDYCHSQGIMHRD 593 K LY TLTDYDIR+Y+YE+LKALDYCHS GIMHRD Sbjct: 122 KQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRD 156
>CSK21_CHICK (P21868) Casein kinase II subunit alpha (EC 2.7.11.1) (CK II)| Length = 391 Score = 204 bits (520), Expect = 1e-52 Identities = 95/155 (61%), Positives = 114/155 (73%) Frame = +3 Query: 129 SSSAMSKARVYADVNVVRPKEYWDYEALAVQWGEQDDYEVVRKVGRGKYSEVFEGINVNN 308 S S+ARVY DVN RP+EYWDYE+ V+WG QDDY++VRK+GRGKYSEVFE IN+ N Sbjct: 2 SGPVPSRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITN 61 Query: 309 NEXXXXXXXXXXXXXXXXXXXXXLQNLCGGPNIVKLLDIVRDQHSKTPSLIFEYINNTDF 488 NE L+NL GGPNI+ L DIV+D S+TP+L+FE++NNTDF Sbjct: 62 NEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDF 121 Query: 489 KVLYPTLTDYDIRYYIYELLKALDYCHSQGIMHRD 593 K LY TLTDYDIR+Y+YE+LKALDYCHS GIMHRD Sbjct: 122 KQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRD 156
>CSK21_BOVIN (P68399) Casein kinase II subunit alpha (EC 2.7.11.1) (CK II)| Length = 391 Score = 204 bits (520), Expect = 1e-52 Identities = 95/155 (61%), Positives = 114/155 (73%) Frame = +3 Query: 129 SSSAMSKARVYADVNVVRPKEYWDYEALAVQWGEQDDYEVVRKVGRGKYSEVFEGINVNN 308 S S+ARVY DVN RP+EYWDYE+ V+WG QDDY++VRK+GRGKYSEVFE IN+ N Sbjct: 2 SGPVPSRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITN 61 Query: 309 NEXXXXXXXXXXXXXXXXXXXXXLQNLCGGPNIVKLLDIVRDQHSKTPSLIFEYINNTDF 488 NE L+NL GGPNI+ L DIV+D S+TP+L+FE++NNTDF Sbjct: 62 NEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDF 121 Query: 489 KVLYPTLTDYDIRYYIYELLKALDYCHSQGIMHRD 593 K LY TLTDYDIR+Y+YE+LKALDYCHS GIMHRD Sbjct: 122 KQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRD 156
>CSK22_XENLA (P28020) Casein kinase II subunit alpha' (EC 2.7.11.1) (CK II)| Length = 392 Score = 203 bits (517), Expect = 3e-52 Identities = 94/155 (60%), Positives = 114/155 (73%) Frame = +3 Query: 129 SSSAMSKARVYADVNVVRPKEYWDYEALAVQWGEQDDYEVVRKVGRGKYSEVFEGINVNN 308 S S+ARVY DVN RP++YWDYE+ V+WG QDDY++VRK+GRGKYSEVFE IN+ N Sbjct: 2 SGPVPSRARVYTDVNTHRPRDYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITN 61 Query: 309 NEXXXXXXXXXXXXXXXXXXXXXLQNLCGGPNIVKLLDIVRDQHSKTPSLIFEYINNTDF 488 NE L+NL GGPNI+ L DIV+D S+TP+L+FE++NNTDF Sbjct: 62 NEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDF 121 Query: 489 KVLYPTLTDYDIRYYIYELLKALDYCHSQGIMHRD 593 K LY TLTDYDIR+Y+YE+LKALDYCHS GIMHRD Sbjct: 122 KQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRD 156
>CSK21_RABIT (P33674) Casein kinase II subunit alpha (EC 2.7.11.1) (CK II)| Length = 391 Score = 202 bits (513), Expect = 8e-52 Identities = 94/155 (60%), Positives = 112/155 (72%) Frame = +3 Query: 129 SSSAMSKARVYADVNVVRPKEYWDYEALAVQWGEQDDYEVVRKVGRGKYSEVFEGINVNN 308 S S+ RVY DVN RP+EYWDYE+ V+WG QDDY++VRK+GRGKYSEVFE IN+ N Sbjct: 2 SGPVPSRVRVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITN 61 Query: 309 NEXXXXXXXXXXXXXXXXXXXXXLQNLCGGPNIVKLLDIVRDQHSKTPSLIFEYINNTDF 488 NE L+NL GGPNI+ L DIV+D S+TP+L FE++NNTDF Sbjct: 62 NEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPASRTPALAFEHVNNTDF 121 Query: 489 KVLYPTLTDYDIRYYIYELLKALDYCHSQGIMHRD 593 K LY TLTDYDIR+Y+YE+LKALDYCHS GIMHRD Sbjct: 122 KQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRD 156
>CSK22_BOVIN (P20427) Casein kinase II subunit alpha' (EC 2.7.11.1) (CK II)| Length = 350 Score = 201 bits (510), Expect = 2e-51 Identities = 95/153 (62%), Positives = 114/153 (74%) Frame = +3 Query: 135 SAMSKARVYADVNVVRPKEYWDYEALAVQWGEQDDYEVVRKVGRGKYSEVFEGINVNNNE 314 +A S+ARVYA+VN +R +EYWDYEA WG QDDY++VRK+GRGKYSEVFE IN+ NNE Sbjct: 5 AARSRARVYAEVNSLRSREYWDYEAHVPSWGNQDDYQLVRKLGRGKYSEVFEAINITNNE 64 Query: 315 XXXXXXXXXXXXXXXXXXXXXLQNLCGGPNIVKLLDIVRDQHSKTPSLIFEYINNTDFKV 494 L+NL GG NI+KL+D V+D SKTP+L+FEYINNTDFK Sbjct: 65 RVVVKILKPVKKKKIKREVKILENLRGGTNIIKLIDTVKDPVSKTPALVFEYINNTDFKQ 124 Query: 495 LYPTLTDYDIRYYIYELLKALDYCHSQGIMHRD 593 LY LTD+DIR+Y+YELLKALDYCHS+GIMHRD Sbjct: 125 LYQILTDFDIRFYMYELLKALDYCHSKGIMHRD 157
>CSK22_MOUSE (O54833) Casein kinase II subunit alpha' (EC 2.7.11.1) (CK II)| Length = 350 Score = 200 bits (508), Expect = 3e-51 Identities = 95/153 (62%), Positives = 114/153 (74%) Frame = +3 Query: 135 SAMSKARVYADVNVVRPKEYWDYEALAVQWGEQDDYEVVRKVGRGKYSEVFEGINVNNNE 314 +A S+ARVYA+VN +R +EYWDYEA WG QDDY++VRK+GRGKYSEVFE IN+ NNE Sbjct: 5 AAGSRARVYAEVNSLRSREYWDYEAHVPSWGNQDDYQLVRKLGRGKYSEVFEAINITNNE 64 Query: 315 XXXXXXXXXXXXXXXXXXXXXLQNLCGGPNIVKLLDIVRDQHSKTPSLIFEYINNTDFKV 494 L+NL GG NI+KL+D V+D SKTP+L+FEYINNTDFK Sbjct: 65 RVVVKILKPVKKKKIKREVKILENLRGGTNIIKLIDTVKDPVSKTPALVFEYINNTDFKQ 124 Query: 495 LYPTLTDYDIRYYIYELLKALDYCHSQGIMHRD 593 LY LTD+DIR+Y+YELLKALDYCHS+GIMHRD Sbjct: 125 LYQILTDFDIRFYMYELLKALDYCHSKGIMHRD 157
>CSK22_HUMAN (P19784) Casein kinase II subunit alpha' (EC 2.7.11.1) (CK II)| Length = 350 Score = 200 bits (508), Expect = 3e-51 Identities = 95/153 (62%), Positives = 114/153 (74%) Frame = +3 Query: 135 SAMSKARVYADVNVVRPKEYWDYEALAVQWGEQDDYEVVRKVGRGKYSEVFEGINVNNNE 314 +A S+ARVYA+VN +R +EYWDYEA WG QDDY++VRK+GRGKYSEVFE IN+ NNE Sbjct: 5 AAGSRARVYAEVNSLRSREYWDYEAHVPSWGNQDDYQLVRKLGRGKYSEVFEAINITNNE 64 Query: 315 XXXXXXXXXXXXXXXXXXXXXLQNLCGGPNIVKLLDIVRDQHSKTPSLIFEYINNTDFKV 494 L+NL GG NI+KL+D V+D SKTP+L+FEYINNTDFK Sbjct: 65 RVVVKILKPVKKKKIKREVKILENLRGGTNIIKLIDTVKDPVSKTPALVFEYINNTDFKQ 124 Query: 495 LYPTLTDYDIRYYIYELLKALDYCHSQGIMHRD 593 LY LTD+DIR+Y+YELLKALDYCHS+GIMHRD Sbjct: 125 LYQILTDFDIRFYMYELLKALDYCHSKGIMHRD 157
>CSK2A_SPOFR (O76484) Casein kinase II subunit alpha (EC 2.7.11.1) (CK II alpha| subunit) Length = 353 Score = 198 bits (503), Expect = 1e-50 Identities = 93/150 (62%), Positives = 111/150 (74%) Frame = +3 Query: 144 SKARVYADVNVVRPKEYWDYEALAVQWGEQDDYEVVRKVGRGKYSEVFEGINVNNNEXXX 323 S+ARVYADVN RP+EYWDYE+ V WG Q+DY++VRK+GRGKYSEVFE IN+ NNE Sbjct: 7 SRARVYADVNSQRPREYWDYESYVVDWGNQEDYQLVRKLGRGKYSEVFEAINITNNEKCV 66 Query: 324 XXXXXXXXXXXXXXXXXXLQNLCGGPNIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYP 503 L+NL GG NI+ L +V+D S+TP+LIFE++NNTDFK LY Sbjct: 67 VKILKPVKKKKIKREIKILENLRGGTNIITLQAVVKDPVSRTPALIFEHVNNTDFKQLYQ 126 Query: 504 TLTDYDIRYYIYELLKALDYCHSQGIMHRD 593 TL+DYDIRYY+YELLKALDYCHS GIMHRD Sbjct: 127 TLSDYDIRYYLYELLKALDYCHSMGIMHRD 156
>CSK22_CHICK (P21869) Casein kinase II subunit alpha' (EC 2.7.11.1) (CK II)| Length = 350 Score = 197 bits (502), Expect = 1e-50 Identities = 94/153 (61%), Positives = 112/153 (73%) Frame = +3 Query: 135 SAMSKARVYADVNVVRPKEYWDYEALAVQWGEQDDYEVVRKVGRGKYSEVFEGINVNNNE 314 +A S+ARVYA+VN +R +EYWDYEA WG QDDY++VRK+GRGKYSEVFE IN+ NNE Sbjct: 5 AAGSRARVYAEVNSLRSREYWDYEAHVPSWGNQDDYQLVRKLGRGKYSEVFEAINITNNE 64 Query: 315 XXXXXXXXXXXXXXXXXXXXXLQNLCGGPNIVKLLDIVRDQHSKTPSLIFEYINNTDFKV 494 L+NL GG NI+ L+D V+D SKTP+L+FEYINNTDFK Sbjct: 65 RVVVKILKPVKKKKIKREVKILENLRGGTNIINLIDTVKDPVSKTPALVFEYINNTDFKQ 124 Query: 495 LYPTLTDYDIRYYIYELLKALDYCHSQGIMHRD 593 LY LTD+DIR+Y+YELLKALDYCHS GIMHRD Sbjct: 125 LYQILTDFDIRFYMYELLKALDYCHSMGIMHRD 157
>CSK2A_SCHPO (P40231) Casein kinase II subunit alpha (EC 2.7.11.1) (CK II alpha| subunit) Length = 332 Score = 196 bits (499), Expect = 3e-50 Identities = 94/155 (60%), Positives = 113/155 (72%) Frame = +3 Query: 129 SSSAMSKARVYADVNVVRPKEYWDYEALAVQWGEQDDYEVVRKVGRGKYSEVFEGINVNN 308 ++ +S +RVYA VN P+EYWDYE + +G QD+YE++RKVGRGKYSEVFEG+NV N Sbjct: 6 AAPVVSVSRVYAHVNEEMPREYWDYENMQEVFGYQDNYEIIRKVGRGKYSEVFEGLNVLN 65 Query: 309 NEXXXXXXXXXXXXXXXXXXXXXLQNLCGGPNIVKLLDIVRDQHSKTPSLIFEYINNTDF 488 N LQNL GGPNI+ LLDIVRD SKTPSLIFE+++N DF Sbjct: 66 NSKCIIKVLKPVKYKKIKREIKILQNLAGGPNIISLLDIVRDPESKTPSLIFEFVDNIDF 125 Query: 489 KVLYPTLTDYDIRYYIYELLKALDYCHSQGIMHRD 593 + LYPTL+DYDIRYY YELLKALD+CHS+GIMHRD Sbjct: 126 RTLYPTLSDYDIRYYSYELLKALDFCHSRGIMHRD 160
>CSK2A_NEUCR (Q8TG13) Casein kinase II subunit alpha (EC 2.7.11.1) (CK II alpha| subunit) Length = 336 Score = 195 bits (496), Expect = 7e-50 Identities = 91/148 (61%), Positives = 109/148 (73%) Frame = +3 Query: 150 ARVYADVNVVRPKEYWDYEALAVQWGEQDDYEVVRKVGRGKYSEVFEGINVNNNEXXXXX 329 ARVYADVN P+ YWDY+++ + WG ++YEVVRK+GRGKYSEVFEGINV N + Sbjct: 2 ARVYADVNQNMPRAYWDYDSVNISWGVLENYEVVRKIGRGKYSEVFEGINVVNYQKCVIK 61 Query: 330 XXXXXXXXXXXXXXXXLQNLCGGPNIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPTL 509 LQNL GGPNIV LLD+VRD SKTPSLIFEY+NNT+F+ LYP Sbjct: 62 VLKPVKKKKIKREIKILQNLAGGPNIVALLDVVRDSQSKTPSLIFEYVNNTEFRTLYPRF 121 Query: 510 TDYDIRYYIYELLKALDYCHSQGIMHRD 593 D+D+RYYI+ELLKALD+CHS+GIMHRD Sbjct: 122 NDFDVRYYIFELLKALDFCHSKGIMHRD 149
>CSK2A_CAEEL (P18334) Casein kinase II subunit alpha (EC 2.7.11.1) (CK II alpha| subunit) Length = 360 Score = 194 bits (494), Expect = 1e-49 Identities = 90/150 (60%), Positives = 114/150 (76%) Frame = +3 Query: 144 SKARVYADVNVVRPKEYWDYEALAVQWGEQDDYEVVRKVGRGKYSEVFEGINVNNNEXXX 323 S+ARVYA+VN RP+EYWDYEA ++WG+ DDY++VRK+GRGKYSEVFEG ++ +E Sbjct: 6 SRARVYAEVNPSRPREYWDYEAHMIEWGQIDDYQLVRKLGRGKYSEVFEGFKMSTDEKVV 65 Query: 324 XXXXXXXXXXXXXXXXXXLQNLCGGPNIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYP 503 L+NL GG NI+ LLD+V+D S+TP+LIFE++NN+DFK LY Sbjct: 66 VKILKPVKKKKIKREIKILENLRGGTNIITLLDVVKDPISRTPALIFEHVNNSDFKQLYQ 125 Query: 504 TLTDYDIRYYIYELLKALDYCHSQGIMHRD 593 TL+DYDIRYY+YELLKALD+CHSQGIMHRD Sbjct: 126 TLSDYDIRYYLYELLKALDFCHSQGIMHRD 155
>CSK2A_DROME (P08181) Casein kinase II subunit alpha (EC 2.7.11.1) (CK II alpha| subunit) Length = 335 Score = 190 bits (482), Expect = 3e-48 Identities = 90/150 (60%), Positives = 106/150 (70%) Frame = +3 Query: 144 SKARVYADVNVVRPKEYWDYEALAVQWGEQDDYEVVRKVGRGKYSEVFEGINVNNNEXXX 323 S ARVY DVN +P EYWDYE V WG QDDY++VRK+GRGKYSEVFE IN+ E Sbjct: 4 SAARVYTDVNAHKPDEYWDYENYVVDWGNQDDYQLVRKLGRGKYSEVFEAINITTTEKCV 63 Query: 324 XXXXXXXXXXXXXXXXXXLQNLCGGPNIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYP 503 L+NL GG NI+ LL +V+D S+TP+LIFE++NNTDFK LY Sbjct: 64 VKILKPVKKKKIKREIKILENLRGGTNIITLLAVVKDPVSRTPALIFEHVNNTDFKQLYQ 123 Query: 504 TLTDYDIRYYIYELLKALDYCHSQGIMHRD 593 TLTDY+IRYY++ELLKALDYCHS GIMHRD Sbjct: 124 TLTDYEIRYYLFELLKALDYCHSMGIMHRD 153
>CSK2A_THEAN (Q4U925) Casein kinase II subunit alpha (EC 2.7.11.1) (CK II)| (TaCKIIalpha) Length = 348 Score = 184 bits (468), Expect = 1e-46 Identities = 86/147 (58%), Positives = 105/147 (71%) Frame = +3 Query: 153 RVYADVNVVRPKEYWDYEALAVQWGEQDDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXX 332 + YADVN + EYWDYE + ++W D YE+VRK+GRGK+SEVFEG+N + Sbjct: 26 KTYADVNSKKGPEYWDYENITLKWNVPDSYEIVRKIGRGKFSEVFEGLNTVTKDKCVIKI 85 Query: 333 XXXXXXXXXXXXXXXLQNLCGGPNIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPTLT 512 LQNL GGPNI+KLLDIV+D S+TPSLIFE++NNTDFK LYPTLT Sbjct: 86 LKPVKKKKIKREIKILQNLRGGPNIIKLLDIVKDPQSRTPSLIFEHVNNTDFKTLYPTLT 145 Query: 513 DYDIRYYIYELLKALDYCHSQGIMHRD 593 DI+YYIY+LLKA++YCHSQGIMHRD Sbjct: 146 IQDIKYYIYQLLKAMNYCHSQGIMHRD 172
>CSK2A_THEPA (P28547) Casein kinase II subunit alpha (EC 2.7.11.1) (CK II)| Length = 348 Score = 184 bits (466), Expect = 2e-46 Identities = 86/147 (58%), Positives = 105/147 (71%) Frame = +3 Query: 153 RVYADVNVVRPKEYWDYEALAVQWGEQDDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXX 332 + YADVN + EYWDYE + ++W D YE+VRK+GRGK+SEVFEGIN + Sbjct: 26 KTYADVNSKKGPEYWDYENITLKWNVPDSYEIVRKIGRGKFSEVFEGINTVTKDKCVIKI 85 Query: 333 XXXXXXXXXXXXXXXLQNLCGGPNIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPTLT 512 LQNL GGPNI+KLLDIV+D S+TPSLIFE++NNTDFK LYPTL+ Sbjct: 86 LKPVKKKKIKREIKILQNLRGGPNIIKLLDIVKDPQSRTPSLIFEHVNNTDFKTLYPTLS 145 Query: 513 DYDIRYYIYELLKALDYCHSQGIMHRD 593 DI+YYIY+LLKA++YCHSQGIMHRD Sbjct: 146 IQDIKYYIYQLLKAMNYCHSQGIMHRD 172
>CSK22_YEAST (P19454) Casein kinase II subunit alpha' (EC 2.7.11.1) (CK II)| Length = 338 Score = 153 bits (387), Expect = 3e-37 Identities = 78/156 (50%), Positives = 96/156 (61%), Gaps = 1/156 (0%) Frame = +3 Query: 129 SSSAMSKARVYADVNVVRPKEYWDYE-ALAVQWGEQDDYEVVRKVGRGKYSEVFEGINVN 305 S+ S ARVY + RP+EYWDYE + + WG+ +YE++ K+GRGKYSEVF G + Sbjct: 11 SNRVYSVARVYKNACEERPQEYWDYEQGVTIDWGKISNYEIINKIGRGKYSEVFSGRCIV 70 Query: 306 NNEXXXXXXXXXXXXXXXXXXXXXLQNLCGGPNIVKLLDIVRDQHSKTPSLIFEYINNTD 485 NN+ L NL GGPN+V L DIV+D SK P+LIFE I N D Sbjct: 71 NNQKCVIKVLKPVKMKKIYRELKILTNLTGGPNVVGLYDIVQDADSKIPALIFEEIKNVD 130 Query: 486 FKVLYPTLTDYDIRYYIYELLKALDYCHSQGIMHRD 593 F+ LYPT DI+YY +LL ALDYCHS GIMHRD Sbjct: 131 FRTLYPTFKLPDIQYYFTQLLIALDYCHSMGIMHRD 166
>CSK21_YEAST (P15790) Casein kinase II subunit alpha (EC 2.7.11.1) (CK II alpha| subunit) Length = 372 Score = 129 bits (325), Expect = 5e-30 Identities = 71/189 (37%), Positives = 95/189 (50%), Gaps = 39/189 (20%) Frame = +3 Query: 144 SKARVYADVNVVRPKEYWDYEALAVQWGEQD-DYEVVRKVGRGKYSEVFEGINVNNNEXX 320 S+ARVY ++N R +EYWDYE + W DYE+ KVGRGKYSEVF+G+ +++ Sbjct: 7 SEARVYTNINKQRTEEYWDYENTVIDWSTNTKDYEIENKVGRGKYSEVFQGVKLDSKVKI 66 Query: 321 XXXXXXXXXXXXXXXXXXXLQNLCGGPNIVKLLDIVRDQH-------------------- 440 L +L L +DQ+ Sbjct: 67 VIKMLKPVKKKKIKREIKILTDLSNEKVPPTTLPFQKDQYYTNQKEDVLKFIRPYIFDQP 126 Query: 441 ------------------SKTPSLIFEYINNTDFKVLYPTLTDYDIRYYIYELLKALDYC 566 SKTP+L+FEY++N DF++LYP LTD +IR+Y++ELLKALDYC Sbjct: 127 HNGHANIIHLFDIIKDPISKTPALVFEYVDNVDFRILYPKLTDLEIRFYMFELLKALDYC 186 Query: 567 HSQGIMHRD 593 HS GIMHRD Sbjct: 187 HSMGIMHRD 195
>CDC2A_ARATH (P24100) Cell division control protein 2 homolog A (EC 2.7.11.22)| (EC 2.7.11.23) Length = 294 Score = 55.5 bits (132), Expect = 1e-07 Identities = 38/129 (29%), Positives = 57/129 (44%), Gaps = 9/129 (6%) Frame = +3 Query: 234 DDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXX----XXXXXXXXLQNLCGGP 401 D YE V K+G G Y V++ + NE L Sbjct: 2 DQYEKVEKIGEGTYGVVYKARDKVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQHS 61 Query: 402 NIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPTLTDYD-----IRYYIYELLKALDYC 566 NIVKL D+V + K L+FEY++ D K + D+ I+ Y+Y++L+ + YC Sbjct: 62 NIVKLQDVVHSE--KRLYLVFEYLD-LDLKKHMDSTPDFSKDLHMIKTYLYQILRGIAYC 118 Query: 567 HSQGIMHRD 593 HS ++HRD Sbjct: 119 HSHRVLHRD 127
>CDC22_ORYSA (P29619) Cell division control protein 2 homolog 2 (EC 2.7.11.22)| Length = 292 Score = 53.1 bits (126), Expect = 6e-07 Identities = 35/128 (27%), Positives = 59/128 (46%), Gaps = 8/128 (6%) Frame = +3 Query: 234 DDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXX----XXXXXXXXLQNLCGGP 401 + YE V K+G G Y V++G + + NE L Sbjct: 2 EQYEKVEKIGEGTYGVVYKGKHRHTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQHR 61 Query: 402 NIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPTLTDYD----IRYYIYELLKALDYCH 569 NIV+L D+V + K L+FEY++ D K + D+ ++ ++Y++L+ + YCH Sbjct: 62 NIVRLQDVVHKE--KCIYLVFEYLD-LDLKKHMDSSPDFKNHRIVKSFLYQILRGIAYCH 118 Query: 570 SQGIMHRD 593 S ++HRD Sbjct: 119 SHRVLHRD 126
>MOK_HUMAN (Q9UQ07) MAPK/MAK/MRK overlapping kinase (EC 2.7.11.22) (MOK| protein kinase) (Renal tumor antigen 1) (RAGE-1) Length = 419 Score = 53.1 bits (126), Expect = 6e-07 Identities = 35/127 (27%), Positives = 64/127 (50%), Gaps = 8/127 (6%) Frame = +3 Query: 237 DYEVVRKVGRGKYSEVFEGINVNNNEXXX----XXXXXXXXXXXXXXXXXXLQNLCGGPN 404 +Y+ + K+G G +SEV + ++ + L+ L PN Sbjct: 3 NYKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQRFESIEQVNNLREIQALRRLNPHPN 62 Query: 405 IVKLLDIVRDQHSKTPSLIFEYINNTDFKVL----YPTLTDYDIRYYIYELLKALDYCHS 572 I+ L ++V D+ S + +LI E ++ ++++ YP L++ I +Y+Y+L K+LD+ H Sbjct: 63 ILMLHEVVFDRKSGSLALICELMDMNIYELIRGRRYP-LSEKKIMHYMYQLCKSLDHIHR 121 Query: 573 QGIMHRD 593 GI HRD Sbjct: 122 NGIFHRD 128
>CDC2_MAIZE (P23111) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) Length = 294 Score = 52.8 bits (125), Expect = 8e-07 Identities = 36/130 (27%), Positives = 60/130 (46%), Gaps = 10/130 (7%) Frame = +3 Query: 234 DDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXX-----XXXXXXXXXLQNLCGG 398 + YE V K+G G Y V++ ++ NE L+ + G Sbjct: 2 EQYEKVEKIGEGTYGVVYKALDKATNETIALKKIRLEQEDEGVPSTAIREISLLKEMNHG 61 Query: 399 PNIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPTLTDYD-----IRYYIYELLKALDY 563 NIV+L D+V + K L+FEY++ D K + ++ I+ Y+Y++L + Y Sbjct: 62 -NIVRLHDVVHSE--KRIYLVFEYLD-LDLKKFMDSCPEFAKNPTLIKSYLYQILHGVAY 117 Query: 564 CHSQGIMHRD 593 CHS ++HRD Sbjct: 118 CHSHRVLHRD 127
>CDC2_CHERU (P93101) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) Length = 294 Score = 52.8 bits (125), Expect = 8e-07 Identities = 37/130 (28%), Positives = 60/130 (46%), Gaps = 10/130 (7%) Frame = +3 Query: 234 DDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXX-----XXXXXXXXXLQNLCGG 398 D YE V K+G G Y V++ + NE L+ + G Sbjct: 2 DQYEKVEKIGEGTYGVVYKARDKVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQHG 61 Query: 399 PNIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPTLTDYD-----IRYYIYELLKALDY 563 NIV+L D+V + K L+FEY++ D K + D+ I+ ++Y++L+ + Y Sbjct: 62 -NIVRLQDVVHSE--KRLYLVFEYLD-LDLKKHMDSCPDFAKDPRMIKRFLYQILRGIAY 117 Query: 564 CHSQGIMHRD 593 CHS ++HRD Sbjct: 118 CHSHRVLHRD 127
>PFTK1_MOUSE (O35495) Serine/threonine-protein kinase PFTAIRE-1 (EC 2.7.11.22)| Length = 469 Score = 52.4 bits (124), Expect = 1e-06 Identities = 35/131 (26%), Positives = 64/131 (48%), Gaps = 6/131 (4%) Frame = +3 Query: 219 QWGEQDDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXXXXXXXXXXLQNLCGG 398 ++G+ D YE + K+G G Y+ V++G + N + +L G Sbjct: 128 KFGKADSYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAIREASLLKG 187 Query: 399 ---PNIVKLLDIVRDQHSKTPSLIFEYINNT--DFKVLYPT-LTDYDIRYYIYELLKALD 560 NIV L DI+ + + T L+FEY++ + +P L +++ ++++LL+ L Sbjct: 188 LKHANIVLLHDIIHTKETLT--LVFEYVHTDLCQYMEQHPGGLHPDNVKLFLFQLLRGLS 245 Query: 561 YCHSQGIMHRD 593 Y H + I+HRD Sbjct: 246 YIHQRYILHRD 256
>PFTK1_HUMAN (O94921) Serine/threonine-protein kinase PFTAIRE-1 (EC 2.7.11.22)| Length = 469 Score = 52.0 bits (123), Expect = 1e-06 Identities = 35/131 (26%), Positives = 64/131 (48%), Gaps = 6/131 (4%) Frame = +3 Query: 219 QWGEQDDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXXXXXXXXXXLQNLCGG 398 ++G+ D YE + K+G G Y+ V++G + N + +L G Sbjct: 128 KFGKADSYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAIREASLLKG 187 Query: 399 ---PNIVKLLDIVRDQHSKTPSLIFEYINNT--DFKVLYPT-LTDYDIRYYIYELLKALD 560 NIV L DI+ + + T L+FEY++ + +P L +++ ++++LL+ L Sbjct: 188 LKHANIVLLHDIIHTKETLT--LVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQLLRGLS 245 Query: 561 YCHSQGIMHRD 593 Y H + I+HRD Sbjct: 246 YIHQRYILHRD 256
>KOK0_YEAST (Q12236) Probable serine/threonine-protein kinase YOL100W (EC| 2.7.11.1) Length = 1081 Score = 52.0 bits (123), Expect = 1e-06 Identities = 29/75 (38%), Positives = 42/75 (56%), Gaps = 3/75 (4%) Frame = +3 Query: 378 LQNLCGGPNIVKLLDIVRDQHSKTPSLIFEYINNTDFKVL---YPTLTDYDIRYYIYELL 548 LQ L P++V+L +D+ S + EY N DF L Y +L + RYY +++ Sbjct: 231 LQKLNNSPSVVRLFSTFQDESSLY--FLLEYAPNGDFLSLMKKYGSLDETCARYYAAQII 288 Query: 549 KALDYCHSQGIMHRD 593 A+DY HS GI+HRD Sbjct: 289 DAIDYLHSNGIIHRD 303
>MK15_HUMAN (Q8TD08) Mitogen-activated protein kinase 15 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 8) Length = 544 Score = 51.2 bits (121), Expect = 2e-06 Identities = 33/126 (26%), Positives = 58/126 (46%), Gaps = 8/126 (6%) Frame = +3 Query: 240 YEVVRKVGRGKYSEVFEGINVNNNEXXXX-----XXXXXXXXXXXXXXXXXLQNLCGGPN 404 Y + R++G+G Y V++ ++ E LQ PN Sbjct: 13 YLLRRQLGQGAYGIVWKAVDRRTGEVVAIKKIFDAFRDKTDAQRTFREITLLQEFGDHPN 72 Query: 405 IVKLLDIVRDQHSKTPSLIFEYINNTDFKVLY---PTLTDYDIRYYIYELLKALDYCHSQ 575 I+ LLD++R ++ + L+FE++ +TD + L D +R Y+LL+A + HS Sbjct: 73 IISLLDVIRAENDRDIYLVFEFM-DTDLNAVIRKGGLLQDVHVRSIFYQLLRATRFLHSG 131 Query: 576 GIMHRD 593 ++HRD Sbjct: 132 HVVHRD 137
>CDK2_XENLA (P23437) Cell division protein kinase 2 (EC 2.7.11.22) (CDC2| homolog Eg1 protein kinase) Length = 297 Score = 50.8 bits (120), Expect = 3e-06 Identities = 32/128 (25%), Positives = 59/128 (46%), Gaps = 8/128 (6%) Frame = +3 Query: 234 DDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXX----XXXXXXXXLQNLCGGP 401 ++++ V K+G G Y V++ N E L P Sbjct: 2 ENFQKVEKIGEGTYGVVYKARNRETGEIVALKKIRLDTETEGVPSTAIREISLLKELNHP 61 Query: 402 NIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPT----LTDYDIRYYIYELLKALDYCH 569 NIVKLLD++ ++ L+FE++N K + + ++ ++ Y+++LL+ L +CH Sbjct: 62 NIVKLLDVIHTENKLY--LVFEFLNQDLKKFMDGSNISGISLALVKSYLFQLLQGLAFCH 119 Query: 570 SQGIMHRD 593 S ++HRD Sbjct: 120 SHRVLHRD 127
>CIPK1_ORYSA (Q6X4A2) CIPK-like protein 1 (EC 2.7.11.1) (OsCK1)| Length = 449 Score = 50.8 bits (120), Expect = 3e-06 Identities = 31/126 (24%), Positives = 57/126 (45%), Gaps = 8/126 (6%) Frame = +3 Query: 240 YEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXXXXXXXXXXLQNLCG-----GPN 404 YE+ R +G G +++V N N+E + +C PN Sbjct: 20 YELGRTIGEGTFAKVRFAKNTENDEPVAIKILDKEKVQKHRLVEQIRREICTMKLVKHPN 79 Query: 405 IVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPT---LTDYDIRYYIYELLKALDYCHSQ 575 +V+L +++ + ++ EY+ + + T L + + R Y +L+ A+DYCHS+ Sbjct: 80 VVRLFEVMGSK--ARIFIVLEYVTGGELFEIIATNGRLKEEEARKYFQQLINAVDYCHSR 137 Query: 576 GIMHRD 593 G+ HRD Sbjct: 138 GVYHRD 143
>CDK5_XENLA (P51166) Cell division protein kinase 5 (EC 2.7.11.22) (Neuronal| cyclin-dependent kinase 5) Length = 292 Score = 50.8 bits (120), Expect = 3e-06 Identities = 35/126 (27%), Positives = 57/126 (45%), Gaps = 8/126 (6%) Frame = +3 Query: 240 YEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXXXXXXXXXXLQNLC-----GGPN 404 YE + K+G G Y VF+ N + +E L+ +C N Sbjct: 4 YEKLEKIGEGTYGTVFKAKNRDTHEIVALKRVRLDDDDEGVPSSA-LREICLLKELKHKN 62 Query: 405 IVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPTLTDYD---IRYYIYELLKALDYCHSQ 575 IV+L D++ T L+FE+ + K D D ++ ++Y+LLK L +CHS+ Sbjct: 63 IVRLHDVLHSDKKLT--LVFEFCDQDLKKYFDSCNGDLDPEIVKSFMYQLLKGLAFCHSR 120 Query: 576 GIMHRD 593 ++HRD Sbjct: 121 NVLHRD 126
>MOK_MOUSE (Q9WVS4) MAPK/MAK/MRK overlapping kinase (EC 2.7.11.22) (MOK| protein kinase) Length = 420 Score = 50.4 bits (119), Expect = 4e-06 Identities = 34/127 (26%), Positives = 63/127 (49%), Gaps = 8/127 (6%) Frame = +3 Query: 237 DYEVVRKVGRGKYSEVFEGINVNNNEXXX----XXXXXXXXXXXXXXXXXXLQNLCGGPN 404 +Y+ + K+G G +SEV + ++ + L+ L PN Sbjct: 3 NYKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQHFESIEQVNSLREIQALRRLNPHPN 62 Query: 405 IVKLLDIVRDQHSKTPSLIFEYINNTDFKVL----YPTLTDYDIRYYIYELLKALDYCHS 572 I+ L ++V D+ S + +LI E ++ ++++ +P L++ I Y+Y+L K+LD+ H Sbjct: 63 ILALHEVVFDRKSGSLALICELMDMNIYELIRGRRHP-LSEKKIMLYMYQLCKSLDHMHR 121 Query: 573 QGIMHRD 593 GI HRD Sbjct: 122 NGIFHRD 128
>CDC7_YEAST (P06243) Cell division control protein 7 (EC 2.7.11.1)| Length = 507 Score = 50.4 bits (119), Expect = 4e-06 Identities = 36/140 (25%), Positives = 59/140 (42%), Gaps = 17/140 (12%) Frame = +3 Query: 225 GEQDDYEVVRKVGRGKYSEVFEGI---------------NVNNNEXXXXXXXXXXXXXXX 359 G +++Y+++ K+G G +S V++ N +N Sbjct: 28 GIENEYKLIDKIGEGTFSSVYKAKDITGKITKKFASHFWNYGSNYVALKKIYVTSSPQRI 87 Query: 360 XXXXXXLQNLCGGPNIVKLLDI--VRDQHSKTPSLIFEYINNTDFKVLYPTLTDYDIRYY 533 L + G + L D VRDQ + Y + +F+ Y L I+ Y Sbjct: 88 YNELNLLYIMTGSSRVAPLCDAKRVRDQ----VIAVLPYYPHEEFRTFYRDLPIKGIKKY 143 Query: 534 IYELLKALDYCHSQGIMHRD 593 I+ELL+AL + HS+GI+HRD Sbjct: 144 IWELLRALKFVHSKGIIHRD 163
>AL2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.11.22)| (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 7 protein) Length = 384 Score = 50.1 bits (118), Expect = 5e-06 Identities = 34/133 (25%), Positives = 63/133 (47%), Gaps = 6/133 (4%) Frame = +3 Query: 213 AVQWGEQDDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXXXXXXXXXXLQNLC 392 ++ +G Y + K+G G Y+ V++GI+ N + +L Sbjct: 43 SLPFGAASSYLNLEKLGEGSYATVYKGISRINGQLVALKVISMNAEEGVPFTAIREASLL 102 Query: 393 GG---PNIVKLLDIVRDQHSKTPSLIFEYINN--TDFKVLYPT-LTDYDIRYYIYELLKA 554 G NIV L DI+ + + T +FEY++ + +P L +++R ++++LL+ Sbjct: 103 KGLKHANIVLLHDIIHTKETLT--FVFEYMHTDLAQYMSQHPGGLHPHNVRLFMFQLLRG 160 Query: 555 LDYCHSQGIMHRD 593 L Y H Q ++HRD Sbjct: 161 LAYIHHQHVLHRD 173
>CDC2A_ANTMA (Q38772) Cell division control protein 2 homolog A (EC 2.7.11.22)| (EC 2.7.11.23) Length = 294 Score = 50.1 bits (118), Expect = 5e-06 Identities = 34/130 (26%), Positives = 60/130 (46%), Gaps = 10/130 (7%) Frame = +3 Query: 234 DDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXX-----XXXXXXXXXLQNLCGG 398 + YE V K+G G Y V++ + NE L+ + G Sbjct: 2 EQYEKVEKIGEGTYGVVYKARDRVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQHG 61 Query: 399 PNIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPTLTDYD-----IRYYIYELLKALDY 563 NIV+L D+V + K L+FEY++ D K + ++ ++ ++Y++L+ + Y Sbjct: 62 -NIVRLQDVVHSE--KRLYLVFEYLD-LDLKKHMDSCPEFSQDPRLVKMFLYQILRGIAY 117 Query: 564 CHSQGIMHRD 593 CHS ++HRD Sbjct: 118 CHSHRVLHRD 127
>CDC2D_ANTMA (Q38775) Cell division control protein 2 homolog D (EC 2.7.11.22)| (EC 2.7.11.23) Length = 312 Score = 50.1 bits (118), Expect = 5e-06 Identities = 30/134 (22%), Positives = 60/134 (44%), Gaps = 14/134 (10%) Frame = +3 Query: 234 DDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXX-----XXXXXXXXLQNLCGG 398 D + + KVG G Y +V+ + + + L+ L Sbjct: 12 DAFVKLEKVGEGTYGKVYRAMEKSTGKIVALKKTRLHEDEEGVPPTTLREVSLLRMLSRD 71 Query: 399 PNIVKLLDIVRDQHSKTPS---LIFEYINNT------DFKVLYPTLTDYDIRYYIYELLK 551 P++V+LLD+ + Q+ + + L+FEY++ FK ++ +++ +Y+L K Sbjct: 72 PHVVRLLDVKQGQNKEGKTVLYLVFEYMDTDLKKYIRSFKQTGESIAPMNVKSLMYQLCK 131 Query: 552 ALDYCHSQGIMHRD 593 + +CH G++HRD Sbjct: 132 GVAFCHGHGVLHRD 145
>CDK2_RAT (Q63699) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 49.7 bits (117), Expect = 6e-06 Identities = 34/128 (26%), Positives = 59/128 (46%), Gaps = 8/128 (6%) Frame = +3 Query: 234 DDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXX----XXXXXXXXLQNLCGGP 401 ++++ V K+G G Y V++ N E L P Sbjct: 2 ENFQKVEKIGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHP 61 Query: 402 NIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPT-LTDYD---IRYYIYELLKALDYCH 569 NIVKLLD++ ++ L+FE+++ K + + LT I+ Y+++LL+ L +CH Sbjct: 62 NIVKLLDVIHTENKLY--LVFEFLHQDLKKFMDASALTGLPLPLIKSYLFQLLQGLAFCH 119 Query: 570 SQGIMHRD 593 S ++HRD Sbjct: 120 SHRVLHRD 127
>CDK2_HUMAN (P24941) Cell division protein kinase 2 (EC 2.7.11.22) (p33 protein| kinase) Length = 298 Score = 49.7 bits (117), Expect = 6e-06 Identities = 34/128 (26%), Positives = 59/128 (46%), Gaps = 8/128 (6%) Frame = +3 Query: 234 DDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXX----XXXXXXXXLQNLCGGP 401 ++++ V K+G G Y V++ N E L P Sbjct: 2 ENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHP 61 Query: 402 NIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPT-LTDYD---IRYYIYELLKALDYCH 569 NIVKLLD++ ++ L+FE+++ K + + LT I+ Y+++LL+ L +CH Sbjct: 62 NIVKLLDVIHTENKLY--LVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCH 119 Query: 570 SQGIMHRD 593 S ++HRD Sbjct: 120 SHRVLHRD 127
>CDK2_BOVIN (Q5E9Y0) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 49.7 bits (117), Expect = 6e-06 Identities = 34/128 (26%), Positives = 59/128 (46%), Gaps = 8/128 (6%) Frame = +3 Query: 234 DDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXX----XXXXXXXXLQNLCGGP 401 ++++ V K+G G Y V++ N E L P Sbjct: 2 ENFQKVEKIGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHP 61 Query: 402 NIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPT-LTDYD---IRYYIYELLKALDYCH 569 NIVKLLD++ ++ L+FE+++ K + + LT I+ Y+++LL+ L +CH Sbjct: 62 NIVKLLDVIHTENKLY--LVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCH 119 Query: 570 SQGIMHRD 593 S ++HRD Sbjct: 120 SHRVLHRD 127
>CDK5_MOUSE (P49615) Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein| kinase II catalytic subunit) (TPKII catalytic subunit) (Serine/threonine-protein kinase PSSALRE) (CRK6) Length = 292 Score = 49.7 bits (117), Expect = 6e-06 Identities = 34/126 (26%), Positives = 56/126 (44%), Gaps = 8/126 (6%) Frame = +3 Query: 240 YEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXXXXXXXXXXLQNLC-----GGPN 404 YE + K+G G Y VF+ N +E L+ +C N Sbjct: 4 YEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSA-LREICLLKELKHKN 62 Query: 405 IVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPTLTDYD---IRYYIYELLKALDYCHSQ 575 IV+L D++ T L+FE+ + K D D ++ ++++LLK L +CHS+ Sbjct: 63 IVRLHDVLHSDKKLT--LVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSR 120 Query: 576 GIMHRD 593 ++HRD Sbjct: 121 NVLHRD 126
>CDK5_HUMAN (Q00535) Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein| kinase II catalytic subunit) (TPKII catalytic subunit) (Serine/threonine-protein kinase PSSALRE) Length = 292 Score = 49.7 bits (117), Expect = 6e-06 Identities = 34/126 (26%), Positives = 56/126 (44%), Gaps = 8/126 (6%) Frame = +3 Query: 240 YEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXXXXXXXXXXLQNLC-----GGPN 404 YE + K+G G Y VF+ N +E L+ +C N Sbjct: 4 YEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSA-LREICLLKELKHKN 62 Query: 405 IVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPTLTDYD---IRYYIYELLKALDYCHSQ 575 IV+L D++ T L+FE+ + K D D ++ ++++LLK L +CHS+ Sbjct: 63 IVRLHDVLHSDKKLT--LVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSR 120 Query: 576 GIMHRD 593 ++HRD Sbjct: 121 NVLHRD 126
>CDK5_BOVIN (Q02399) Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein| kinase II catalytic subunit) (TPKII catalytic subunit) (Proline-directed protein kinase 33 kDa subunit) (PDPK) Length = 292 Score = 49.7 bits (117), Expect = 6e-06 Identities = 34/126 (26%), Positives = 56/126 (44%), Gaps = 8/126 (6%) Frame = +3 Query: 240 YEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXXXXXXXXXXLQNLC-----GGPN 404 YE + K+G G Y VF+ N +E L+ +C N Sbjct: 4 YEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSA-LREICLLKELKHKN 62 Query: 405 IVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPTLTDYD---IRYYIYELLKALDYCHSQ 575 IV+L D++ T L+FE+ + K D D ++ ++++LLK L +CHS+ Sbjct: 63 IVRLHDVLHSDKKLT--LVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSR 120 Query: 576 GIMHRD 593 ++HRD Sbjct: 121 NVLHRD 126
>CDK2_MOUSE (P97377) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 346 Score = 49.7 bits (117), Expect = 6e-06 Identities = 34/128 (26%), Positives = 59/128 (46%), Gaps = 8/128 (6%) Frame = +3 Query: 234 DDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXX----XXXXXXXXLQNLCGGP 401 ++++ V K+G G Y V++ N E L P Sbjct: 2 ENFQKVEKIGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHP 61 Query: 402 NIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPT-LTDYD---IRYYIYELLKALDYCH 569 NIVKLLD++ ++ L+FE+++ K + + LT I+ Y+++LL+ L +CH Sbjct: 62 NIVKLLDVIHTENKLY--LVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCH 119 Query: 570 SQGIMHRD 593 S ++HRD Sbjct: 120 SHRVLHRD 127
>CDK3_HUMAN (Q00526) Cell division protein kinase 3 (EC 2.7.11.22)| Length = 305 Score = 48.9 bits (115), Expect = 1e-05 Identities = 33/128 (25%), Positives = 58/128 (45%), Gaps = 8/128 (6%) Frame = +3 Query: 234 DDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXX----XXXXXXXXLQNLCGGP 401 D ++ V K+G G Y V++ N + L P Sbjct: 2 DMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKHP 61 Query: 402 NIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPT----LTDYDIRYYIYELLKALDYCH 569 NIV+LLD+V ++ L+FE+++ K + T L + I+ Y+++LL+ + +CH Sbjct: 62 NIVRLLDVVHNERKLY--LVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQLLQGVSFCH 119 Query: 570 SQGIMHRD 593 S ++HRD Sbjct: 120 SHRVIHRD 127
>CDC2_CARAU (P51958) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 302 Score = 48.9 bits (115), Expect = 1e-05 Identities = 35/129 (27%), Positives = 60/129 (46%), Gaps = 9/129 (6%) Frame = +3 Query: 234 DDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXX----XXXXXXXXLQNLCGGP 401 DDY + K+G G Y V++G N + L P Sbjct: 2 DDYLKIEKIGEGTYGVVYKGRNKTTGQVVAMKKIRLESEEEGVPSTAVREISLLKELQHP 61 Query: 402 NIVKLLDIVRDQHSKTPSLIFEYINNTDFKVL--YPTLTDYD---IRYYIYELLKALDYC 566 N+V+LLD++ Q SK L+FE+++ K L P+ D ++ Y+Y++L+ + +C Sbjct: 62 NVVRLLDVLM-QESKL-YLVFEFLSMDLKKYLDSIPSGQFMDPMLVKSYLYQILEGILFC 119 Query: 567 HSQGIMHRD 593 H + ++HRD Sbjct: 120 HCRRVLHRD 128
>CDK5_DROME (P48609) Cell division protein kinase 5 homolog (EC 2.7.11.22)| Length = 294 Score = 48.5 bits (114), Expect = 1e-05 Identities = 35/127 (27%), Positives = 60/127 (47%), Gaps = 9/127 (7%) Frame = +3 Query: 240 YEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXXXXXXXXXXLQNLC-----GGPN 404 Y+ + K+G G Y VF+G N + E L+ +C N Sbjct: 4 YDKMEKIGEGTYGTVFKGRNRDTMEIVALKRVRLDEDDEGVPSSA-LREICLLKELKHKN 62 Query: 405 IVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPTLT-DYDI---RYYIYELLKALDYCHS 572 IV+L+D++ T L+FE+ + D K + +L + D+ R ++ +LL+ L +CHS Sbjct: 63 IVRLIDVLHSDKKLT--LVFEHCDQ-DLKKYFDSLNGEIDMAVCRSFMLQLLRGLAFCHS 119 Query: 573 QGIMHRD 593 ++HRD Sbjct: 120 HNVLHRD 126
>CDC22_MEDSA (Q05006) Cell division control protein 2 homolog 2 (EC 2.7.11.22)| Length = 294 Score = 48.5 bits (114), Expect = 1e-05 Identities = 34/129 (26%), Positives = 56/129 (43%), Gaps = 9/129 (6%) Frame = +3 Query: 234 DDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXX----XXXXXXXXLQNLCGGP 401 + YE V K+G G Y V++ + NE L Sbjct: 2 EQYEKVEKIGEGTYGVVYKARDRATNETIALKKIRLEQEDEGVPSTAIREISLLKEMQHR 61 Query: 402 NIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPTLTDY-----DIRYYIYELLKALDYC 566 NIV+L D+V + K L+FEY++ D K + ++ I+ ++Y++L + YC Sbjct: 62 NIVRLQDVVHSE--KRLYLVFEYLD-LDLKKFMDSSPEFAKDQRQIKMFLYQILCGIAYC 118 Query: 567 HSQGIMHRD 593 HS ++HRD Sbjct: 119 HSHRVLHRD 127
>CDC21_ORYSA (P29618) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| Length = 294 Score = 48.5 bits (114), Expect = 1e-05 Identities = 34/130 (26%), Positives = 58/130 (44%), Gaps = 10/130 (7%) Frame = +3 Query: 234 DDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXX-----XXXXXXXXXLQNLCGG 398 + YE K+G G Y V+ + NE L+ + G Sbjct: 2 EQYEKEEKIGEGTYGVVYRARDKVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMHHG 61 Query: 399 PNIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPTLTDYD-----IRYYIYELLKALDY 563 NIV+L D++ + K L+FEY++ D K + ++ I+ Y+Y++L+ + Y Sbjct: 62 -NIVRLHDVIHSE--KRIYLVFEYLD-LDLKKFMDSCPEFAKNPTLIKSYLYQILRGVAY 117 Query: 564 CHSQGIMHRD 593 CHS ++HRD Sbjct: 118 CHSHRVLHRD 127
>CDK2_CRIGR (O55076) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 48.5 bits (114), Expect = 1e-05 Identities = 32/128 (25%), Positives = 57/128 (44%), Gaps = 8/128 (6%) Frame = +3 Query: 234 DDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXX----XXXXXXXXLQNLCGGP 401 ++++ V K+G G Y V++ N E L P Sbjct: 2 ENFQKVEKIGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHP 61 Query: 402 NIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPTLTDYD----IRYYIYELLKALDYCH 569 NIVKLLD++ ++ L+FE+++ K + + I+ Y+++LL+ L +CH Sbjct: 62 NIVKLLDVIHTENKLY--LVFEFLHQDLKKFMDASAVTGIPLPLIKSYLFQLLQGLAFCH 119 Query: 570 SQGIMHRD 593 S ++HRD Sbjct: 120 SHRVLHRD 127
>CDK5_RAT (Q03114) Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein| kinase II catalytic subunit) (TPKII catalytic subunit) (Serine/threonine-protein kinase PSSALRE) Length = 292 Score = 48.1 bits (113), Expect = 2e-05 Identities = 34/126 (26%), Positives = 55/126 (43%), Gaps = 8/126 (6%) Frame = +3 Query: 240 YEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXXXXXXXXXXLQNLC-----GGPN 404 YE + K+G G Y VF+ N +E L+ +C N Sbjct: 4 YEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSA-LREICLLKELKHKN 62 Query: 405 IVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPTLTDYD---IRYYIYELLKALDYCHSQ 575 IV+L D++ T L+FE+ + K D D ++ +++LLK L +CHS+ Sbjct: 63 IVRLHDVLHSDKKLT--LVFEFCDQDLKKYFDSCNGDLDPEIVKSLLFQLLKGLGFCHSR 120 Query: 576 GIMHRD 593 ++HRD Sbjct: 121 NVLHRD 126
>CDC22_XENLA (P24033) Cell division control protein 2 homolog 2 (EC 2.7.11.22)| (EC 2.7.11.23) (p34 protein kinase 2) Length = 302 Score = 48.1 bits (113), Expect = 2e-05 Identities = 36/129 (27%), Positives = 61/129 (47%), Gaps = 9/129 (6%) Frame = +3 Query: 234 DDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXX----XXXXXXXXLQNLCGGP 401 D+Y + K+G G Y V++G + + L P Sbjct: 2 DEYTKIEKIGEGTYGVVYKGRHKATGQVVAMKKIRLENEEEGVPSTAIREISLLKELQHP 61 Query: 402 NIVKLLDIVRDQHSKTPSLIFEYINNTDFKVL--YPTLTDYD---IRYYIYELLKALDYC 566 NIV LLD++ Q S+ LIFE+++ K L P+ D ++ Y+Y++L+ + +C Sbjct: 62 NIVCLLDVLM-QDSRL-YLIFEFLSMDVKKYLDSIPSGQYIDTMLVKSYLYQILQGIVFC 119 Query: 567 HSQGIMHRD 593 HS+G++HRD Sbjct: 120 HSRGVLHRD 128
>SSP1_SCHPO (P50526) Serine/threonine-protein kinase ssp1 (EC 2.7.11.1)| Length = 652 Score = 47.8 bits (112), Expect = 2e-05 Identities = 31/133 (23%), Positives = 56/133 (42%), Gaps = 15/133 (11%) Frame = +3 Query: 240 YEVVRKVGRGKYSEVFEGINVNNNEXXXXXX------------XXXXXXXXXXXXXXXLQ 383 YE+++++GRG + +V G + E + Sbjct: 135 YEIIKELGRGMHGKVKLGRDTVTRELLAIKIIPKTERRPKLGRANASSQKEKVRREIAIL 194 Query: 384 NLCGGPNIVKLLDIVRDQHSKTPSLIFEYINNTDFKVL---YPTLTDYDIRYYIYELLKA 554 C PN+V+L +++ D S L+ EY++ + P L+ + R Y +++ Sbjct: 195 KKCVHPNVVRLREVIDDPSSTKVYLVLEYMSGGEVPWTDCDSPVLSISEARQYFRDVVLG 254 Query: 555 LDYCHSQGIMHRD 593 L+Y H QGI+HRD Sbjct: 255 LEYLHYQGIIHRD 267
>PCTK2_RAT (O35831) Serine/threonine-protein kinase PCTAIRE-2 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 2) Length = 523 Score = 47.8 bits (112), Expect = 2e-05 Identities = 34/133 (25%), Positives = 61/133 (45%), Gaps = 7/133 (5%) Frame = +3 Query: 216 VQWGEQDDYEVVRKVGRGKYSEVFEG---INVNNNEXXXXXXXXXXXXXXXXXXXXXLQN 386 + +G+ + Y + K+G G Y+ V++G + N L Sbjct: 184 IGFGKMETYIKLEKLGEGTYATVYKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLK 243 Query: 387 LCGGPNIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPT----LTDYDIRYYIYELLKA 554 NIV L DIV S T L+FEY++ D K ++ ++++ ++Y++L+ Sbjct: 244 DLKHANIVTLHDIVHTDKSLT--LVFEYLDK-DLKQYMDDCGSIMSMHNVKLFLYQILRG 300 Query: 555 LDYCHSQGIMHRD 593 L YCH + ++HRD Sbjct: 301 LAYCHRRKVLHRD 313
>PCTK2_MOUSE (Q8K0D0) Serine/threonine-protein kinase PCTAIRE-2 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 2) Length = 523 Score = 47.8 bits (112), Expect = 2e-05 Identities = 34/133 (25%), Positives = 61/133 (45%), Gaps = 7/133 (5%) Frame = +3 Query: 216 VQWGEQDDYEVVRKVGRGKYSEVFEG---INVNNNEXXXXXXXXXXXXXXXXXXXXXLQN 386 + +G+ + Y + K+G G Y+ V++G + N L Sbjct: 184 IGFGKMETYIKLEKLGEGTYATVYKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLK 243 Query: 387 LCGGPNIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPT----LTDYDIRYYIYELLKA 554 NIV L DIV S T L+FEY++ D K ++ ++++ ++Y++L+ Sbjct: 244 DLKHANIVTLHDIVHTDKSLT--LVFEYLDK-DLKQYMDDCGNIMSMHNVKLFLYQILRG 300 Query: 555 LDYCHSQGIMHRD 593 L YCH + ++HRD Sbjct: 301 LAYCHRRKVLHRD 313
>PCTK2_HUMAN (Q00537) Serine/threonine-protein kinase PCTAIRE-2 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 2) Length = 523 Score = 47.8 bits (112), Expect = 2e-05 Identities = 34/133 (25%), Positives = 61/133 (45%), Gaps = 7/133 (5%) Frame = +3 Query: 216 VQWGEQDDYEVVRKVGRGKYSEVFEG---INVNNNEXXXXXXXXXXXXXXXXXXXXXLQN 386 + +G+ + Y + K+G G Y+ V++G + N L Sbjct: 184 IGFGKMETYIKLEKLGEGTYATVYKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLK 243 Query: 387 LCGGPNIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPT----LTDYDIRYYIYELLKA 554 NIV L DIV S T L+FEY++ D K ++ ++++ ++Y++L+ Sbjct: 244 DLKHANIVTLHDIVHTDKSLT--LVFEYLDK-DLKQYMDDCGNIMSMHNVKLFLYQILRG 300 Query: 555 LDYCHSQGIMHRD 593 L YCH + ++HRD Sbjct: 301 LAYCHRRKVLHRD 313
>PHO85_CANGA (Q6FKD4) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 302 Score = 47.4 bits (111), Expect = 3e-05 Identities = 32/130 (24%), Positives = 59/130 (45%), Gaps = 12/130 (9%) Frame = +3 Query: 240 YEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXXXXXXXXX---XLQNLCGGPNIV 410 ++ + K+G G Y+ V++G+N + L NIV Sbjct: 6 FKQLEKLGNGTYATVYKGLNKSTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHDNIV 65 Query: 411 KLLDIVRDQHSKTPSLIFEYINNTDFKVLYPTLTDYD---------IRYYIYELLKALDY 563 +L D++ ++ T L+FEY++N D K + T + ++Y+ ++LL+ L + Sbjct: 66 RLYDVIHTENKLT--LVFEYMDN-DLKKYMDSRTVGNAPRGLEMNLVKYFQWQLLEGLAF 122 Query: 564 CHSQGIMHRD 593 CH I+HRD Sbjct: 123 CHENKILHRD 132
>KKCC2_RAT (O88831) Calcium/calmodulin-dependent protein kinase kinase 2 (EC| 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-kinase kinase beta) (CaM-KK beta) (CaMKK beta) Length = 587 Score = 47.4 bits (111), Expect = 3e-05 Identities = 23/68 (33%), Positives = 41/68 (60%), Gaps = 3/68 (4%) Frame = +3 Query: 399 PNIVKLLDIVRDQHSKTPSLIFEYINN---TDFKVLYPTLTDYDIRYYIYELLKALDYCH 569 PN+VKL++++ D + ++FE +N + L P L++ R+Y +L+K ++Y H Sbjct: 245 PNVVKLVEVLDDPNEDHLYMVFELVNQGPVMEVPTLKP-LSEDQARFYFQDLIKGIEYLH 303 Query: 570 SQGIMHRD 593 Q I+HRD Sbjct: 304 YQKIIHRD 311
>CDK2_CARAU (P43450) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 47.4 bits (111), Expect = 3e-05 Identities = 33/129 (25%), Positives = 56/129 (43%), Gaps = 9/129 (6%) Frame = +3 Query: 234 DDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXX----XXXXXXXXLQNLCGGP 401 + ++ V K+G G Y V++ N E L P Sbjct: 2 ESFQKVEKIGEGTYGVVYKAKNKVTGETVALKKIRLDTETEGVPSTAIREISLLKELNHP 61 Query: 402 NIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPTLTDYDI-----RYYIYELLKALDYC 566 NIVKL D++ ++ L+FE+++ D K + T I + Y+++LL+ L +C Sbjct: 62 NIVKLHDVIHTENKLY--LVFEFLHQ-DLKRFMDSSTVTGISLPLVKSYLFQLLQGLAFC 118 Query: 567 HSQGIMHRD 593 HS ++HRD Sbjct: 119 HSHRVLHRD 127
>MK15_RAT (Q9Z2A6) Mitogen-activated protein kinase 15 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 7) Length = 547 Score = 47.4 bits (111), Expect = 3e-05 Identities = 32/126 (25%), Positives = 57/126 (45%), Gaps = 8/126 (6%) Frame = +3 Query: 240 YEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXXXXXXXXXX-----LQNLCGGPN 404 Y + R++G+G Y V++ ++ E L+ G PN Sbjct: 14 YLIKRRLGKGAYGIVWKAMDRRTGEVVAIKKIFDAFRDQTDAQRTFREIMLLREFGGHPN 73 Query: 405 IVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPT---LTDYDIRYYIYELLKALDYCHSQ 575 I++LLD++ ++ + L+FE ++ TD + L D R Y+LL+A + HS Sbjct: 74 IIRLLDVIPAKNDRDIYLVFESMD-TDLNAVIQKGRLLEDIHKRCIFYQLLRATKFIHSG 132 Query: 576 GIMHRD 593 ++HRD Sbjct: 133 RVIHRD 138
>CDKL1_BRARE (Q6AXJ9) Cyclin-dependent kinase-like 1 (EC 2.7.11.22)| Length = 350 Score = 47.4 bits (111), Expect = 3e-05 Identities = 31/127 (24%), Positives = 58/127 (45%), Gaps = 7/127 (5%) Frame = +3 Query: 234 DDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXX----XXXXXXXXLQNLCGGP 401 + YE + K+G G Y VF+ N + + + P Sbjct: 2 EKYEKISKIGEGSYGVVFKCRNKDTGQIVAIKKFVESEDDPIIKKIALREIRMLKQLKHP 61 Query: 402 NIVKLLDIVRDQHSKTPSLIFEYINNTDFKVL--YPT-LTDYDIRYYIYELLKALDYCHS 572 N+V L+++ R + L+FEY ++T L YP + ++ ++ I++ L+A+++CH Sbjct: 62 NLVNLMEVFR--RKRKLHLVFEYCDHTVLNELDRYPRGVPEHMVKSIIWQTLQAVNFCHK 119 Query: 573 QGIMHRD 593 Q +HRD Sbjct: 120 QNCIHRD 126
>KKCC2_MOUSE (Q8C078) Calcium/calmodulin-dependent protein kinase kinase 2 (EC| 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-kinase kinase beta) (CaM-KK beta) (CaMKK beta) Length = 588 Score = 47.4 bits (111), Expect = 3e-05 Identities = 23/68 (33%), Positives = 41/68 (60%), Gaps = 3/68 (4%) Frame = +3 Query: 399 PNIVKLLDIVRDQHSKTPSLIFEYINN---TDFKVLYPTLTDYDIRYYIYELLKALDYCH 569 PN+VKL++++ D + ++FE +N + L P L++ R+Y +L+K ++Y H Sbjct: 246 PNVVKLVEVLDDPNEDHLYMVFELVNQGPVMEVPTLKP-LSEDQARFYFQDLIKGIEYLH 304 Query: 570 SQGIMHRD 593 Q I+HRD Sbjct: 305 YQKIIHRD 312
>KKCC2_HUMAN (Q96RR4) Calcium/calmodulin-dependent protein kinase kinase 2 (EC| 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-kinase kinase beta) (CaM-KK beta) (CaMKK beta) Length = 588 Score = 47.4 bits (111), Expect = 3e-05 Identities = 23/68 (33%), Positives = 41/68 (60%), Gaps = 3/68 (4%) Frame = +3 Query: 399 PNIVKLLDIVRDQHSKTPSLIFEYINN---TDFKVLYPTLTDYDIRYYIYELLKALDYCH 569 PN+VKL++++ D + ++FE +N + L P L++ R+Y +L+K ++Y H Sbjct: 246 PNVVKLVEVLDDPNEDHLYMVFELVNQGPVMEVPTLKP-LSEDQARFYFQDLIKGIEYLH 304 Query: 570 SQGIMHRD 593 Q I+HRD Sbjct: 305 YQKIIHRD 312
>CDK2_MESAU (P48963) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 47.0 bits (110), Expect = 4e-05 Identities = 32/128 (25%), Positives = 56/128 (43%), Gaps = 8/128 (6%) Frame = +3 Query: 234 DDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXX----XXXXXXXXLQNLCGGP 401 ++++ V K+G G Y V++ N E L P Sbjct: 2 ENFQKVEKIGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHP 61 Query: 402 NIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPTLTDYD----IRYYIYELLKALDYCH 569 NIVKLLD++ ++ L+FE ++ K + + I+ Y+++LL+ L +CH Sbjct: 62 NIVKLLDVIHTENKLY--LVFELLHQDLKKFMDASAVTGIPLPLIKSYLFQLLQGLAFCH 119 Query: 570 SQGIMHRD 593 S ++HRD Sbjct: 120 SHRVLHRD 127
>PCTK1_RAT (Q63686) Serine/threonine-protein kinase PCTAIRE-1 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 1) Length = 496 Score = 47.0 bits (110), Expect = 4e-05 Identities = 34/133 (25%), Positives = 61/133 (45%), Gaps = 7/133 (5%) Frame = +3 Query: 216 VQWGEQDDYEVVRKVGRGKYSEVFEG---INVNNNEXXXXXXXXXXXXXXXXXXXXXLQN 386 + +G+ + Y + K+G G Y+ V++G + N L Sbjct: 157 IGFGKLETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLK 216 Query: 387 LCGGPNIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYP----TLTDYDIRYYIYELLKA 554 NIV L DI+ + S T L+FEY++ D K + ++++ ++++LL+ Sbjct: 217 DLKHANIVTLHDIIHTEKSLT--LVFEYLDK-DLKQYLDDCGNVINMHNVKLFLFQLLRG 273 Query: 555 LDYCHSQGIMHRD 593 L YCH Q ++HRD Sbjct: 274 LAYCHRQKVLHRD 286
>PCTK1_MOUSE (Q04735) Serine/threonine-protein kinase PCTAIRE-1 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 1) (CRK5) Length = 496 Score = 47.0 bits (110), Expect = 4e-05 Identities = 34/133 (25%), Positives = 61/133 (45%), Gaps = 7/133 (5%) Frame = +3 Query: 216 VQWGEQDDYEVVRKVGRGKYSEVFEG---INVNNNEXXXXXXXXXXXXXXXXXXXXXLQN 386 + +G+ + Y + K+G G Y+ V++G + N L Sbjct: 157 IGFGKLETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLK 216 Query: 387 LCGGPNIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYP----TLTDYDIRYYIYELLKA 554 NIV L DI+ + S T L+FEY++ D K + ++++ ++++LL+ Sbjct: 217 DLKHANIVTLHDIIHTEKSLT--LVFEYLDK-DLKQYLDDCGNVINMHNVKLFLFQLLRG 273 Query: 555 LDYCHSQGIMHRD 593 L YCH Q ++HRD Sbjct: 274 LAYCHRQKVLHRD 286
>PCTK3_PONPY (Q5RD01) Serine/threonine-protein kinase PCTAIRE-3 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 3) Length = 472 Score = 47.0 bits (110), Expect = 4e-05 Identities = 35/134 (26%), Positives = 64/134 (47%), Gaps = 8/134 (5%) Frame = +3 Query: 216 VQWGEQDDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXX----XXXXXXXXLQ 383 + +G+ + Y + K+G G Y+ VF+G + L+ Sbjct: 134 IGFGKLETYVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLK 193 Query: 384 NLCGGPNIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYP----TLTDYDIRYYIYELLK 551 NL NIV L D++ S T L+FEY+++ D K ++ ++++ ++++LL+ Sbjct: 194 NLKHA-NIVTLHDLIHTDRSLT--LVFEYLDS-DLKQYLDHCGNLMSMHNVKIFMFQLLR 249 Query: 552 ALDYCHSQGIMHRD 593 L YCH + I+HRD Sbjct: 250 GLAYCHHRKILHRD 263
>CDC2_DICDI (P34112) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) Length = 296 Score = 47.0 bits (110), Expect = 4e-05 Identities = 33/122 (27%), Positives = 52/122 (42%), Gaps = 4/122 (3%) Frame = +3 Query: 240 YEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXXXXXXXXXXLQNL--CGGPNIVK 413 Y+ + K+G G Y +V++ + L PN+V Sbjct: 10 YQKLEKLGEGTYGKVYKAKEKATGRMVALKKIRLEDDGVPSTALREISLLKEVPHPNVVS 69 Query: 414 LLDIVRDQHSKTPSLIFEYINNTDFKVL--YPTLTDYDIRYYIYELLKALDYCHSQGIMH 587 L D++ Q+ L+FEY++ K + P L I+ Y+Y+LLK L Y H I+H Sbjct: 70 LFDVLHCQNRLY--LVFEYLDQDLKKYMDSVPALCPQLIKSYLYQLLKGLAYSHGHRILH 127 Query: 588 RD 593 RD Sbjct: 128 RD 129
>MK15_MOUSE (Q80Y86) Mitogen-activated protein kinase 15 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 7) Length = 549 Score = 47.0 bits (110), Expect = 4e-05 Identities = 32/126 (25%), Positives = 57/126 (45%), Gaps = 8/126 (6%) Frame = +3 Query: 240 YEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXXXXXXXXXX-----LQNLCGGPN 404 Y + R++G+G Y V++ ++ E L+ G PN Sbjct: 14 YLIKRRLGKGAYGIVWKAMDRRTGEVVAIKKIFDAFRDQIDAQRTFREIMLLKEFGGHPN 73 Query: 405 IVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPT---LTDYDIRYYIYELLKALDYCHSQ 575 I++LLD++ ++ + L+FE ++ TD + L D R Y+LL+A + HS Sbjct: 74 IIRLLDVIPAKNDRDIYLVFESMD-TDLNAVIQKGRLLKDIHKRCIFYQLLRATKFIHSG 132 Query: 576 GIMHRD 593 ++HRD Sbjct: 133 RVIHRD 138
>CDC2_VIGAC (Q41639) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) Length = 294 Score = 46.6 bits (109), Expect = 5e-05 Identities = 33/129 (25%), Positives = 56/129 (43%), Gaps = 9/129 (6%) Frame = +3 Query: 234 DDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXX----XXXXXXXXLQNLCGGP 401 + YE V K+G G Y V++ + NE L Sbjct: 2 EQYEKVEKIGEGTYGVVYKARDRVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQHR 61 Query: 402 NIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPTLTDY-----DIRYYIYELLKALDYC 566 NIV+L D+V + K L+FEY++ D K + ++ ++ ++Y++L + YC Sbjct: 62 NIVRLQDVVHSE--KRLYLVFEYLD-LDLKKHMDSSPEFVKDPRQVKMFLYQILCGIAYC 118 Query: 567 HSQGIMHRD 593 HS ++HRD Sbjct: 119 HSHRVLHRD 127
>PCTK1_HUMAN (Q00536) Serine/threonine-protein kinase PCTAIRE-1 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 1) Length = 496 Score = 46.6 bits (109), Expect = 5e-05 Identities = 34/133 (25%), Positives = 61/133 (45%), Gaps = 7/133 (5%) Frame = +3 Query: 216 VQWGEQDDYEVVRKVGRGKYSEVFEG---INVNNNEXXXXXXXXXXXXXXXXXXXXXLQN 386 + +G+ + Y + K+G G Y+ V++G + N L Sbjct: 157 IGFGKLETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLK 216 Query: 387 LCGGPNIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPT----LTDYDIRYYIYELLKA 554 NIV L DI+ + S T L+FEY++ D K + ++++ ++++LL+ Sbjct: 217 DLKHANIVTLHDIIHTEKSLT--LVFEYLDK-DLKQYLDDCGNIINMHNVKLFLFQLLRG 273 Query: 555 LDYCHSQGIMHRD 593 L YCH Q ++HRD Sbjct: 274 LAYCHRQKVLHRD 286
>CDC2_ORYLU (Q9DG98) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 46.6 bits (109), Expect = 5e-05 Identities = 35/130 (26%), Positives = 63/130 (48%), Gaps = 10/130 (7%) Frame = +3 Query: 234 DDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXX-----XXXXXXXXXLQNLCGG 398 +DY + K+G G Y V++G + + + LQ L Sbjct: 2 EDYVKIEKIGEGTYGVVYKGRHKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQEL-KH 60 Query: 399 PNIVKLLDIVRDQHSKTPSLIFEYINNTDFKVL--YPTLTDYD---IRYYIYELLKALDY 563 PN+V+LLD++ Q S+ LIFE+++ K L P+ D ++ Y+Y++L+ + + Sbjct: 61 PNVVRLLDVLM-QESRL-YLIFEFLSMDLKKYLDSIPSGQYMDPMLVKSYLYQILEGIYF 118 Query: 564 CHSQGIMHRD 593 CH + ++HRD Sbjct: 119 CHRRRVLHRD 128
>CDC2_ORYLA (Q9DGD3) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 46.6 bits (109), Expect = 5e-05 Identities = 35/130 (26%), Positives = 63/130 (48%), Gaps = 10/130 (7%) Frame = +3 Query: 234 DDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXX-----XXXXXXXXXLQNLCGG 398 +DY + K+G G Y V++G + + + LQ L Sbjct: 2 EDYVKIEKIGEGTYGVVYKGRHKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQEL-KH 60 Query: 399 PNIVKLLDIVRDQHSKTPSLIFEYINNTDFKVL--YPTLTDYD---IRYYIYELLKALDY 563 PN+V+LLD++ Q S+ LIFE+++ K L P+ D ++ Y+Y++L+ + + Sbjct: 61 PNVVRLLDVLM-QESRL-YLIFEFLSMDLKKYLDSIPSGQYMDPMLVKSYLYQILEGIYF 118 Query: 564 CHSQGIMHRD 593 CH + ++HRD Sbjct: 119 CHRRRVLHRD 128
>CDC2_ORYJA (Q9DGA2) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 46.6 bits (109), Expect = 5e-05 Identities = 35/130 (26%), Positives = 63/130 (48%), Gaps = 10/130 (7%) Frame = +3 Query: 234 DDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXX-----XXXXXXXXXLQNLCGG 398 +DY + K+G G Y V++G + + + LQ L Sbjct: 2 EDYVKIEKIGEGTYGVVYKGRHKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQEL-KH 60 Query: 399 PNIVKLLDIVRDQHSKTPSLIFEYINNTDFKVL--YPTLTDYD---IRYYIYELLKALDY 563 PN+V+LLD++ Q S+ LIFE+++ K L P+ D ++ Y+Y++L+ + + Sbjct: 61 PNVVRLLDVLM-QESRL-YLIFEFLSMDLKKYLDSIPSGQYMDPMLVKSYLYQILEGIYF 118 Query: 564 CHSQGIMHRD 593 CH + ++HRD Sbjct: 119 CHRRRVLHRD 128
>CDC2_ORYCU (Q9DGA5) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 46.6 bits (109), Expect = 5e-05 Identities = 35/130 (26%), Positives = 63/130 (48%), Gaps = 10/130 (7%) Frame = +3 Query: 234 DDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXX-----XXXXXXXXXLQNLCGG 398 +DY + K+G G Y V++G + + + LQ L Sbjct: 2 EDYVKIEKIGEGTYGVVYKGRHKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQEL-KH 60 Query: 399 PNIVKLLDIVRDQHSKTPSLIFEYINNTDFKVL--YPTLTDYD---IRYYIYELLKALDY 563 PN+V+LLD++ Q S+ LIFE+++ K L P+ D ++ Y+Y++L+ + + Sbjct: 61 PNVVRLLDVLM-QESRL-YLIFEFLSMDLKKYLDSIPSGQYMDPMLVKSYLYQILEGIYF 118 Query: 564 CHSQGIMHRD 593 CH + ++HRD Sbjct: 119 CHRRRVLHRD 128
>PHO85_DEBHA (Q6BRY2) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 330 Score = 46.2 bits (108), Expect = 7e-05 Identities = 30/131 (22%), Positives = 56/131 (42%), Gaps = 8/131 (6%) Frame = +3 Query: 225 GEQDDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXXXXXXXXX---XLQNLCG 395 G ++ + K+G G Y+ V++G N N + L Sbjct: 3 GSSSQFQQLEKLGEGTYATVYKGRNRTNGQLVALKEINLDSEEGTPSTAIREISLMKELD 62 Query: 396 GPNIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYP-----TLTDYDIRYYIYELLKALD 560 NIV L D++ ++ T L+FE+++ K + L ++ +I++LLK + Sbjct: 63 HENIVTLYDVIHTENKLT--LVFEFMDKDLKKYMEAHGNQGALDLKIVKSFIFQLLKGIM 120 Query: 561 YCHSQGIMHRD 593 +CH ++HRD Sbjct: 121 FCHDNRVLHRD 131
>CDK6_MOUSE (Q64261) Cell division protein kinase 6 (EC 2.7.11.22)| (Serine/threonine-protein kinase PLSTIRE) (CRK2) Length = 326 Score = 46.2 bits (108), Expect = 7e-05 Identities = 32/133 (24%), Positives = 59/133 (44%), Gaps = 15/133 (11%) Frame = +3 Query: 240 YEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXXXXXXXXXXLQNLC--------G 395 YE V ++G G Y +VF+ ++ N ++ + Sbjct: 13 YECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTSEEGMPLSTIREVAVLRHLETFE 72 Query: 396 GPNIVKLLDIV---RDQHSKTPSLIFEYINN--TDF--KVLYPTLTDYDIRYYIYELLKA 554 PN+V+L D+ R +L+FE+++ T + KV P + I+ +++LL+ Sbjct: 73 HPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQLLRG 132 Query: 555 LDYCHSQGIMHRD 593 LD+ HS ++HRD Sbjct: 133 LDFLHSHRVVHRD 145
>PCTK3_HUMAN (Q07002) Serine/threonine-protein kinase PCTAIRE-3 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 3) Length = 472 Score = 46.2 bits (108), Expect = 7e-05 Identities = 35/134 (26%), Positives = 64/134 (47%), Gaps = 8/134 (5%) Frame = +3 Query: 216 VQWGEQDDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXX----XXXXXXXXLQ 383 + +G+ + Y + K+G G Y+ VF+G + L+ Sbjct: 134 IGFGKLETYVKLDKLGEGTYATVFKGRSKLMENLVALKEIRLEHEEGAPCTAIREVSLLK 193 Query: 384 NLCGGPNIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYP----TLTDYDIRYYIYELLK 551 NL NIV L D++ S T L+FEY+++ D K ++ ++++ ++++LL+ Sbjct: 194 NLKHA-NIVTLHDLIHTDRSLT--LVFEYLDS-DLKQYLDHCGNLMSMHNVKIFMFQLLR 249 Query: 552 ALDYCHSQGIMHRD 593 L YCH + I+HRD Sbjct: 250 GLAYCHHRKILHRD 263
>PCTK3_RAT (O35832) Serine/threonine-protein kinase PCTAIRE-3 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 3) Length = 451 Score = 46.2 bits (108), Expect = 7e-05 Identities = 34/133 (25%), Positives = 61/133 (45%), Gaps = 7/133 (5%) Frame = +3 Query: 216 VQWGEQDDYEVVRKVGRGKYSEVFEG---INVNNNEXXXXXXXXXXXXXXXXXXXXXLQN 386 + +G+ + Y + K+G G Y+ VF+G + N L Sbjct: 113 IGFGKLETYVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLK 172 Query: 387 LCGGPNIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYP----TLTDYDIRYYIYELLKA 554 NIV L D++ S T L+FEY+++ D K + ++++ ++++LL+ Sbjct: 173 DLKHANIVTLHDLIHTDRSLT--LVFEYLDS-DLKQYLDHCGNLMNMHNVKIFMFQLLRG 229 Query: 555 LDYCHSQGIMHRD 593 L YCH + I+HRD Sbjct: 230 LAYCHRRKILHRD 242
>PCTK3_MOUSE (Q04899) Serine/threonine-protein kinase PCTAIRE-3 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 3) Length = 451 Score = 46.2 bits (108), Expect = 7e-05 Identities = 34/133 (25%), Positives = 61/133 (45%), Gaps = 7/133 (5%) Frame = +3 Query: 216 VQWGEQDDYEVVRKVGRGKYSEVFEG---INVNNNEXXXXXXXXXXXXXXXXXXXXXLQN 386 + +G+ + Y + K+G G Y+ VF+G + N L Sbjct: 113 IGFGKLETYVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLK 172 Query: 387 LCGGPNIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYP----TLTDYDIRYYIYELLKA 554 NIV L D++ S T L+FEY+++ D K + ++++ ++++LL+ Sbjct: 173 DLKHANIVTLHDLIHTDRSLT--LVFEYLDS-DLKQYLDHCGNLMNMHNVKIFMFQLLRG 229 Query: 555 LDYCHSQGIMHRD 593 L YCH + I+HRD Sbjct: 230 LAYCHHRKILHRD 242
>CDKL3_MACFA (Q4R8T9) Cyclin-dependent kinase-like 3 (EC 2.7.11.22)| Length = 590 Score = 45.8 bits (107), Expect = 9e-05 Identities = 33/124 (26%), Positives = 54/124 (43%), Gaps = 6/124 (4%) Frame = +3 Query: 240 YEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXX---XXXXXXXXXXXLQNLCGGPNIV 410 YE + KVG G Y V + + N + N+V Sbjct: 4 YETLGKVGEGSYGTVMKCKHKNTGQIVAIKIFYERPEQSVNKIAMREIKFLKQFHHENLV 63 Query: 411 KLLDIVRDQHSKTPSLIFEYINNTDFKVLYPT---LTDYDIRYYIYELLKALDYCHSQGI 581 L+++ R + K L+FE+I++T L L +R Y++++L+A+DY HS I Sbjct: 64 NLIEVFRQK--KKIHLVFEFIDHTVLDELQHYCHGLESKRLRKYLFQILRAIDYLHSNNI 121 Query: 582 MHRD 593 +HRD Sbjct: 122 IHRD 125
>CDC2_RANDY (Q9W739) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) Length = 302 Score = 45.8 bits (107), Expect = 9e-05 Identities = 32/130 (24%), Positives = 60/130 (46%), Gaps = 10/130 (7%) Frame = +3 Query: 234 DDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXX----XXXXXXXXLQNLCGGP 401 D+Y + K+G G Y V++G++ + L P Sbjct: 2 DEYAKIEKIGEGTYGVVYKGVHKATGQIVAMKKIRLENEEEGVPSTAIREISLLKELQHP 61 Query: 402 NIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPTLTDYD------IRYYIYELLKALDY 563 NIV LLD++ Q S+ LIFE+++ D K ++ ++ Y+Y++L+ + + Sbjct: 62 NIVCLLDVLM-QDSRL-YLIFEFLS-MDLKKYLDSIPSGQYLEAMLVKSYLYQILQGIIF 118 Query: 564 CHSQGIMHRD 593 CH++ ++HRD Sbjct: 119 CHARRVLHRD 128
>CDKL2_MACFA (Q4R7T5) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| Length = 570 Score = 45.8 bits (107), Expect = 9e-05 Identities = 22/67 (32%), Positives = 43/67 (64%), Gaps = 3/67 (4%) Frame = +3 Query: 402 NIVKLLDIVRDQHSKTPSLIFEYINNT--DFKVLYPTLTDYDI-RYYIYELLKALDYCHS 572 N+V LL++ + + K L+FE++++T D L+P DY + + Y+++++ + +CHS Sbjct: 62 NLVNLLEVCKKK--KRWYLVFEFVDHTILDDLELFPNGLDYQVVQKYLFQIINGIGFCHS 119 Query: 573 QGIMHRD 593 I+HRD Sbjct: 120 HNIIHRD 126
>CDK6_HUMAN (Q00534) Cell division protein kinase 6 (EC 2.7.11.22)| (Serine/threonine-protein kinase PLSTIRE) Length = 326 Score = 45.8 bits (107), Expect = 9e-05 Identities = 32/133 (24%), Positives = 59/133 (44%), Gaps = 15/133 (11%) Frame = +3 Query: 240 YEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXXXXXXXXXXLQNLC--------G 395 YE V ++G G Y +VF+ ++ N ++ + Sbjct: 13 YECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLRHLETFE 72 Query: 396 GPNIVKLLDIV---RDQHSKTPSLIFEYINN--TDF--KVLYPTLTDYDIRYYIYELLKA 554 PN+V+L D+ R +L+FE+++ T + KV P + I+ +++LL+ Sbjct: 73 HPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQLLRG 132 Query: 555 LDYCHSQGIMHRD 593 LD+ HS ++HRD Sbjct: 133 LDFLHSHRVVHRD 145
>CDC2H_THEPA (Q27032) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 298 Score = 45.8 bits (107), Expect = 9e-05 Identities = 34/126 (26%), Positives = 54/126 (42%), Gaps = 8/126 (6%) Frame = +3 Query: 240 YEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXX----XXXXXXXXLQNLCGGPNI 407 Y + K+G G Y V++ N N+ E L PNI Sbjct: 4 YHKMEKIGEGTYGVVYKAQN-NHGEICALKKIRVEEEDEGIPSTAIREISLLKELHHPNI 62 Query: 408 VKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPT----LTDYDIRYYIYELLKALDYCHSQ 575 V L D++ + K +L+FEY++ D K L L + ++Y++L+ + YCH Sbjct: 63 VWLRDVIHSE--KCLTLVFEYLDQ-DLKKLLDACDGGLEPTTAKSFLYQILRGISYCHDH 119 Query: 576 GIMHRD 593 I+HRD Sbjct: 120 RILHRD 125
>CDC2H_THEAN (Q26671) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 298 Score = 45.8 bits (107), Expect = 9e-05 Identities = 34/126 (26%), Positives = 54/126 (42%), Gaps = 8/126 (6%) Frame = +3 Query: 240 YEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXX----XXXXXXXXLQNLCGGPNI 407 Y + K+G G Y V++ N N+ E L PNI Sbjct: 4 YHKMEKIGEGTYGVVYKAQN-NHGEICALKKIRVEEEDEGIPSTAIREISLLKELHHPNI 62 Query: 408 VKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPT----LTDYDIRYYIYELLKALDYCHSQ 575 V L D++ + K +L+FEY++ D K L L + ++Y++L+ + YCH Sbjct: 63 VWLRDVIHSE--KCLTLVFEYLDQ-DLKKLLDACDGGLEPTTAKSFLYQILRGISYCHDH 119 Query: 576 GIMHRD 593 I+HRD Sbjct: 120 RILHRD 125
>POLO_DROME (P52304) Serine/threonine-protein kinase polo (EC 2.7.11.21)| Length = 576 Score = 45.8 bits (107), Expect = 9e-05 Identities = 30/134 (22%), Positives = 59/134 (44%), Gaps = 8/134 (5%) Frame = +3 Query: 216 VQWGEQDDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXXXXXXXXXXLQNLC- 392 V ++ Y+ +R G+G +++ +E I+V ++ Q + Sbjct: 17 VDINQRKTYKRMRFFGKGGFAKCYEIIDVETDDVFAGKIVSKKLMIKHNQKEKTAQEITI 76 Query: 393 ----GGPNIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYP---TLTDYDIRYYIYELLK 551 PNIVK + D S+ ++ E L+ ++T+++ RYYIY++++ Sbjct: 77 HRSLNHPNIVKFHNYFED--SQNIYIVLELCKKRSMMELHKRRKSITEFECRYYIYQIIQ 134 Query: 552 ALDYCHSQGIMHRD 593 + Y H I+HRD Sbjct: 135 GVKYLHDNRIIHRD 148
>M4K3_MOUSE (Q99JP0) Mitogen-activated protein kinase kinase kinase kinase 3| (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 3) (MEK kinase kinase 3) (MEKKK 3) (Germinal center kinase-related protein kinase) (GLK) (Fragments) Length = 681 Score = 45.8 bits (107), Expect = 9e-05 Identities = 34/128 (26%), Positives = 55/128 (42%), Gaps = 7/128 (5%) Frame = +3 Query: 231 QDDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXX--XXXXXXXXXXXXLQNLCGGPN 404 Q+D+E+++++G G Y +V++ NVN E + C PN Sbjct: 13 QEDFELIQRIGSGTYGDVYKARNVNTGELAAIKVIKLEPGEDFAVVQQEIIMMKDCKHPN 72 Query: 405 IVKLLD--IVRDQHSKTPSLIFEYINNTDFKVLYPT---LTDYDIRYYIYELLKALDYCH 569 IV + RD+ + E+ + +Y L++ I Y E L+ L Y H Sbjct: 73 IVAYFGSYLRRDK----LWICMEFCGGGSLQDIYHVTGPLSELQIAYVSRETLQGLYYLH 128 Query: 570 SQGIMHRD 593 S+G MHRD Sbjct: 129 SKGKMHRD 136
>CDKL2_PONPY (Q5R754) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| Length = 493 Score = 45.8 bits (107), Expect = 9e-05 Identities = 22/67 (32%), Positives = 43/67 (64%), Gaps = 3/67 (4%) Frame = +3 Query: 402 NIVKLLDIVRDQHSKTPSLIFEYINNT--DFKVLYPTLTDYDI-RYYIYELLKALDYCHS 572 N+V LL++ + + K L+FE++++T D L+P DY + + Y+++++ + +CHS Sbjct: 62 NLVNLLEVCKKK--KRWYLVFEFVDHTILDDLELFPNGLDYQVVQKYLFQIINGIGFCHS 119 Query: 573 QGIMHRD 593 I+HRD Sbjct: 120 HNIIHRD 126
>CDKL2_HUMAN (Q92772) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| (Serine/threonine-protein kinase KKIAMRE) (Protein kinase p56 KKIAMRE) Length = 493 Score = 45.8 bits (107), Expect = 9e-05 Identities = 22/67 (32%), Positives = 43/67 (64%), Gaps = 3/67 (4%) Frame = +3 Query: 402 NIVKLLDIVRDQHSKTPSLIFEYINNT--DFKVLYPTLTDYDI-RYYIYELLKALDYCHS 572 N+V LL++ + + K L+FE++++T D L+P DY + + Y+++++ + +CHS Sbjct: 62 NLVNLLEVCKKK--KRWYLVFEFVDHTILDDLELFPNGLDYQVVQKYLFQIINGIGFCHS 119 Query: 573 QGIMHRD 593 I+HRD Sbjct: 120 HNIIHRD 126
>M4K3_HUMAN (Q8IVH8) Mitogen-activated protein kinase kinase kinase kinase 3| (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 3) (MEK kinase kinase 3) (MEKKK 3) (Germinal center kinase-related protein kinase) (GLK) Length = 894 Score = 45.8 bits (107), Expect = 9e-05 Identities = 34/128 (26%), Positives = 55/128 (42%), Gaps = 7/128 (5%) Frame = +3 Query: 231 QDDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXX--XXXXXXXXXXXXLQNLCGGPN 404 Q+D+E+++++G G Y +V++ NVN E + C PN Sbjct: 13 QEDFELIQRIGSGTYGDVYKARNVNTGELAAIKVIKLEPGEDFAVVQQEIIMMKDCKHPN 72 Query: 405 IVKLLD--IVRDQHSKTPSLIFEYINNTDFKVLYPT---LTDYDIRYYIYELLKALDYCH 569 IV + RD+ + E+ + +Y L++ I Y E L+ L Y H Sbjct: 73 IVAYFGSYLRRDK----LWICMEFCGGGSLQDIYHVTGPLSELQIAYVSRETLQGLYYLH 128 Query: 570 SQGIMHRD 593 S+G MHRD Sbjct: 129 SKGKMHRD 136
>CDKL2_MOUSE (Q9QUK0) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| (Serine/threonine-protein kinase KKIAMRE) Length = 568 Score = 45.8 bits (107), Expect = 9e-05 Identities = 22/67 (32%), Positives = 43/67 (64%), Gaps = 3/67 (4%) Frame = +3 Query: 402 NIVKLLDIVRDQHSKTPSLIFEYINNT--DFKVLYPTLTDYDI-RYYIYELLKALDYCHS 572 N+V LL++ + + K L+FE++++T D L+P DY + + Y+++++ + +CHS Sbjct: 62 NLVNLLEVCKKK--KRWYLVFEFVDHTILDDLKLFPNGLDYQVVQKYLFQIINGIGFCHS 119 Query: 573 QGIMHRD 593 I+HRD Sbjct: 120 HNIIHRD 126
>CDKL2_RAT (Q5XIT0) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| Length = 507 Score = 45.8 bits (107), Expect = 9e-05 Identities = 22/67 (32%), Positives = 43/67 (64%), Gaps = 3/67 (4%) Frame = +3 Query: 402 NIVKLLDIVRDQHSKTPSLIFEYINNT--DFKVLYPTLTDYDI-RYYIYELLKALDYCHS 572 N+V LL++ + + K L+FE++++T D L+P DY + + Y+++++ + +CHS Sbjct: 62 NLVNLLEVCKKK--KRWYLVFEFVDHTILDDLKLFPNGLDYQVVQKYLFQIINGIGFCHS 119 Query: 573 QGIMHRD 593 I+HRD Sbjct: 120 HNIIHRD 126
>CDKL3_HUMAN (Q8IVW4) Cyclin-dependent kinase-like 3 (EC 2.7.11.22)| (Serine/threonine protein kinase NKIAMRE) Length = 592 Score = 45.8 bits (107), Expect = 9e-05 Identities = 33/124 (26%), Positives = 54/124 (43%), Gaps = 6/124 (4%) Frame = +3 Query: 240 YEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXX---XXXXXXXXXXXLQNLCGGPNIV 410 YE + KVG G Y V + + N + N+V Sbjct: 4 YETLGKVGEGSYGTVMKCKHKNTGQIVAIKIFYERPEQSVNKIAMREIKFLKQFHHENLV 63 Query: 411 KLLDIVRDQHSKTPSLIFEYINNTDFKVLYPT---LTDYDIRYYIYELLKALDYCHSQGI 581 L+++ R + K L+FE+I++T L L +R Y++++L+A+DY HS I Sbjct: 64 NLIEVFRQK--KKIHLVFEFIDHTVLDELQHYCHGLESKRLRKYLFQILRAIDYLHSNNI 121 Query: 582 MHRD 593 +HRD Sbjct: 122 IHRD 125
>PHO85_YEAST (P17157) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 305 Score = 45.4 bits (106), Expect = 1e-04 Identities = 31/130 (23%), Positives = 58/130 (44%), Gaps = 12/130 (9%) Frame = +3 Query: 240 YEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXXXXXXXXX---XLQNLCGGPNIV 410 ++ + K+G G Y+ V++G+N L NIV Sbjct: 7 FKQLEKLGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHENIV 66 Query: 411 KLLDIVRDQHSKTPSLIFEYINNTDFKVLYPTLTDYD---------IRYYIYELLKALDY 563 +L D++ ++ T L+FE+++N D K + T + ++Y+ ++LL+ L + Sbjct: 67 RLYDVIHTENKLT--LVFEFMDN-DLKKYMDSRTVGNTPRGLELNLVKYFQWQLLQGLAF 123 Query: 564 CHSQGIMHRD 593 CH I+HRD Sbjct: 124 CHENKILHRD 133
>PHO85_ASHGO (Q751E8) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 303 Score = 45.4 bits (106), Expect = 1e-04 Identities = 29/130 (22%), Positives = 58/130 (44%), Gaps = 12/130 (9%) Frame = +3 Query: 240 YEVVRKVGRGKYSEVFEGINVNNN---EXXXXXXXXXXXXXXXXXXXXXLQNLCGGPNIV 410 ++ + ++G G Y+ V++G+N L NIV Sbjct: 9 FKQLERLGNGTYATVYKGLNKTTGLYVALKEVKLDSEEGTPSTAIREISLMKELKHENIV 68 Query: 411 KLLDIVRDQHSKTPSLIFEYINNTDFKVLYPTLTDYD---------IRYYIYELLKALDY 563 +L D++ ++ T L+FE+++N D K + D + ++Y+ ++LL+ + + Sbjct: 69 RLYDVIHTENKLT--LVFEFMDN-DLKKFMDSRLDREMPRGLELSLVKYFQWQLLQGVAF 125 Query: 564 CHSQGIMHRD 593 CH I+HRD Sbjct: 126 CHENRILHRD 135
>CDC2C_DROME (P23573) Cell division control protein 2 cognate (EC 2.7.11.22) (EC| 2.7.11.23) Length = 314 Score = 45.4 bits (106), Expect = 1e-04 Identities = 34/129 (26%), Positives = 60/129 (46%), Gaps = 9/129 (6%) Frame = +3 Query: 234 DDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXX-----XXXXXXXXLQNLCGG 398 D+++ K+G G Y V++ + + + L+NL Sbjct: 6 DNFQRAEKIGEGTYGIVYKARSNSTGQDVALKKIRLEGETEGVPSTAIREISLLKNL-KH 64 Query: 399 PNIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYP----TLTDYDIRYYIYELLKALDYC 566 PN+V+L D+V ++ +IFEY+N D K L T I+ Y++++L A+ +C Sbjct: 65 PNVVQLFDVVISGNNLY--MIFEYLN-MDLKKLMDKKKDVFTPQLIKSYMHQILDAVGFC 121 Query: 567 HSQGIMHRD 593 H+ I+HRD Sbjct: 122 HTNRILHRD 130
>PHO85_YARLI (Q6C7U8) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 294 Score = 45.4 bits (106), Expect = 1e-04 Identities = 29/127 (22%), Positives = 56/127 (44%), Gaps = 9/127 (7%) Frame = +3 Query: 240 YEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXXXXXXXXX---XLQNLCGGPNIV 410 ++ + K+G G Y+ V++G N + L NIV Sbjct: 7 FQQLEKLGEGTYATVYKGRNRTTGQLVALKEINLDSEEGTPSTAIREISLMKELKHENIV 66 Query: 411 KLLDIVRDQHSKTPSLIFEYINNTDFKVLYPT------LTDYDIRYYIYELLKALDYCHS 572 L D++ ++ +L+FEY++ D K T L +++++Y+LL+ + +CH Sbjct: 67 TLYDVIHTENKL--NLVFEYMDK-DLKKFMDTNGNKGALETKQVKWFMYQLLRGILFCHD 123 Query: 573 QGIMHRD 593 ++HRD Sbjct: 124 NRVLHRD 130
>MMK2_MEDSA (Q40353) Mitogen-activated protein kinase homolog MMK2 (EC| 2.7.11.24) Length = 371 Score = 45.1 bits (105), Expect = 2e-04 Identities = 30/124 (24%), Positives = 51/124 (41%), Gaps = 9/124 (7%) Frame = +3 Query: 249 VRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXXXXXXXXXX----LQNLCGGPNIVKL 416 +R VGRG Y V +N E L N++ + Sbjct: 40 IRSVGRGAYGIVCAAVNAETREEVAIKKIGNAFDNRIDAKRTLREIKLLRHMDHENVMSI 99 Query: 417 LDIVRDQHSKTPSLIF--EYINNTDFKVLYPT---LTDYDIRYYIYELLKALDYCHSQGI 581 DI+R + + ++ + +TD + + +TD RY++Y+LL+ L Y HS + Sbjct: 100 KDIIRPPQKENFNHVYIVSELMDTDLHQIIRSNQPMTDDHCRYFVYQLLRGLKYVHSANV 159 Query: 582 MHRD 593 +HRD Sbjct: 160 LHRD 163
>CDC2C_ANTMA (Q38774) Cell division control protein 2 homolog C (EC 2.7.11.22)| (EC 2.7.11.23) Length = 305 Score = 45.1 bits (105), Expect = 2e-04 Identities = 32/138 (23%), Positives = 58/138 (42%), Gaps = 18/138 (13%) Frame = +3 Query: 234 DDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXX-----XXXXXXXXLQNLCGG 398 + YE + KVG G Y +V++ + + + LQ L Sbjct: 2 EKYEKLEKVGEGTYGKVYKALEKSTGQVVALKKTRLEMDEEGVPPTALREVSLLQMLSQS 61 Query: 399 PNIVKLLDIVRDQHSKTPS----LIFEYINNTDFKVLYPT---------LTDYDIRYYIY 539 +V+LL + +K L+FEY++ TD K + L I+ +++ Sbjct: 62 LYVVRLLSVEHVDCAKNGKPLLYLVFEYLD-TDLKKFIDSHRKGPNPRPLPPQQIQSFLF 120 Query: 540 ELLKALDYCHSQGIMHRD 593 +L K + +CH+ G++HRD Sbjct: 121 QLCKGVSHCHAHGVLHRD 138
>CDC2H_DICDI (P34117) CDC2-like serine/threonine-protein kinase CRP (EC| 2.7.11.22) (EC 2.7.11.23) Length = 292 Score = 45.1 bits (105), Expect = 2e-04 Identities = 23/68 (33%), Positives = 40/68 (58%), Gaps = 3/68 (4%) Frame = +3 Query: 399 PNIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPT---LTDYDIRYYIYELLKALDYCH 569 PNIV+L D++ + T L+FEY++ K L ++ I+ ++Y+LLK + +CH Sbjct: 61 PNIVRLHDVIHTERKLT--LVFEYLDQDLKKYLDECGGEISKPTIKSFMYQLLKGVAFCH 118 Query: 570 SQGIMHRD 593 ++HRD Sbjct: 119 DHRVLHRD 126
>PHO85_KLULA (Q92241) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 304 Score = 45.1 bits (105), Expect = 2e-04 Identities = 30/129 (23%), Positives = 57/129 (44%), Gaps = 11/129 (8%) Frame = +3 Query: 240 YEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXXXXXXXXX---XLQNLCGGPNIV 410 ++ + KVG G Y+ V++G+N L NIV Sbjct: 7 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHDNIV 66 Query: 411 KLLDIVRDQHSKTPSLIFEYINNTDFKVL--------YPTLTDYDIRYYIYELLKALDYC 566 +L D++ ++ T L+FE+++N K + + L ++Y+ ++LL+ + +C Sbjct: 67 RLFDVIHTENKLT--LVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAFC 124 Query: 567 HSQGIMHRD 593 H I+HRD Sbjct: 125 HENRILHRD 133
>CDC21_XENLA (P35567) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| (EC 2.7.11.23) (p34 protein kinase 1) Length = 302 Score = 44.7 bits (104), Expect = 2e-04 Identities = 35/129 (27%), Positives = 60/129 (46%), Gaps = 9/129 (6%) Frame = +3 Query: 234 DDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXX----XXXXXXXXLQNLCGGP 401 D+Y + K+G G Y V++G + + L P Sbjct: 2 DEYTKIEKIGEGTYGVVYKGRHKATGQVVAMKKIRLENEEEGVPSTAIREISLLKELQHP 61 Query: 402 NIVKLLDIVRDQHSKTPSLIFEYINNTDFKVL--YPTLTDYD---IRYYIYELLKALDYC 566 NIV LLD++ Q S+ LIFE+++ K L P+ D ++ Y+Y++L+ + +C Sbjct: 62 NIVCLLDVLM-QDSRL-YLIFEFLSMDLKKYLDSIPSGQYIDTMLVKSYLYQILQGIVFC 119 Query: 567 HSQGIMHRD 593 HS+ ++HRD Sbjct: 120 HSRRVLHRD 128
>CDC2_VIGUN (P52389) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) Length = 294 Score = 44.7 bits (104), Expect = 2e-04 Identities = 32/129 (24%), Positives = 56/129 (43%), Gaps = 9/129 (6%) Frame = +3 Query: 234 DDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXX----XXXXXXXXLQNLCGGP 401 + YE V K+G G Y V++ + +E L Sbjct: 2 EQYEKVEKIGEGTYGVVYKARDRVTDETIALKKIRLEQEDEGVPSTAIREISLLKEMQHR 61 Query: 402 NIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPTLTDY-----DIRYYIYELLKALDYC 566 NIV+L D+V + K L+FEY++ D K + ++ ++ ++Y++L + YC Sbjct: 62 NIVRLQDVVHSE--KRLYLVFEYLD-LDLKKHMDSSPEFVKDPRQVKMFLYQILCGIAYC 118 Query: 567 HSQGIMHRD 593 HS ++HRD Sbjct: 119 HSHRVLHRD 127
>NTF6_TOBAC (Q40531) Mitogen-activated protein kinase homolog NTF6 (EC| 2.7.11.24) (P43) Length = 371 Score = 44.7 bits (104), Expect = 2e-04 Identities = 25/69 (36%), Positives = 39/69 (56%), Gaps = 5/69 (7%) Frame = +3 Query: 402 NIVKLLDIVR--DQHSKTPSLIFEYINNTDFKVLYPT---LTDYDIRYYIYELLKALDYC 566 NI+K+ DIVR D+ I + +TD + + LTD +Y++Y+LL+ L Y Sbjct: 96 NIIKIKDIVRPPDREEFNDVYIVYELMDTDLHQIIRSSQALTDDHCQYFLYQLLRGLKYV 155 Query: 567 HSQGIMHRD 593 HS ++HRD Sbjct: 156 HSANVLHRD 164
>CDKL2_RABIT (Q9TTK0) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| (Serine/threonine-protein kinase KKIAMRE) Length = 566 Score = 44.7 bits (104), Expect = 2e-04 Identities = 22/67 (32%), Positives = 43/67 (64%), Gaps = 3/67 (4%) Frame = +3 Query: 402 NIVKLLDIVRDQHSKTPSLIFEYINNT--DFKVLYPT-LTDYDIRYYIYELLKALDYCHS 572 N+V LL++ + + K L+FE++++T D L+P L D ++ Y+++++ + +CHS Sbjct: 62 NLVNLLEVCKKK--KRWYLVFEFVDHTILDDLELFPNGLDDQVVQKYLFQIINGIGFCHS 119 Query: 573 QGIMHRD 593 I+HRD Sbjct: 120 HNIIHRD 126
>PEF1_SCHPO (O74456) Serine/threonine-protein kinase pef1 (EC 2.7.11.22)| (Cyclin-dependent kinase pef1) (PHO85 homolog) Length = 288 Score = 44.7 bits (104), Expect = 2e-04 Identities = 31/128 (24%), Positives = 54/128 (42%), Gaps = 9/128 (7%) Frame = +3 Query: 237 DYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXXXXXXXXX---XLQNLCGGPNI 407 +Y+ + K+G G Y+ V++G N E L PNI Sbjct: 2 NYQRLEKLGEGTYAHVYKGQNRVTGEIVALKVIRIDADEGTPSTAIREISLMKELRHPNI 61 Query: 408 VKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPT------LTDYDIRYYIYELLKALDYCH 569 + L D+++ ++ L+FEY+ D K T L ++ + +LLK + +CH Sbjct: 62 MSLSDVLQTENKLM--LVFEYMEK-DLKKYMDTYGNQGALPPSQVKNFTQQLLKGISFCH 118 Query: 570 SQGIMHRD 593 ++HRD Sbjct: 119 ENRVLHRD 126
>MK13_HUMAN (O15264) Mitogen-activated protein kinase 13 (EC 2.7.11.24)| (Stress-activated protein kinase 4) (Mitogen-activated protein kinase p38 delta) (MAP kinase p38 delta) Length = 365 Score = 44.3 bits (103), Expect = 3e-04 Identities = 32/150 (21%), Positives = 58/150 (38%), Gaps = 8/150 (5%) Frame = +3 Query: 168 VNVVRPKEYWDYEALAVQWGEQDDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXX 347 ++++R K ++ + W Y VG G Y V I+ + E Sbjct: 1 MSLIRKKGFYKQDVNKTAWELPKTYVSPTHVGSGAYGSVCSAIDKRSGEKVAIKKLSRPF 60 Query: 348 XXXXXXXXXXLQNLC----GGPNIVKLLDIVRDQHSKTPS----LIFEYINNTDFKVLYP 503 + L N++ LLD+ S L+ ++ K++ Sbjct: 61 QSEIFAKRAYRELLLLKHMQHENVIGLLDVFTPASSLRNFYDFYLVMPFMQTDLQKIMGM 120 Query: 504 TLTDYDIRYYIYELLKALDYCHSQGIMHRD 593 ++ I+Y +Y++LK L Y HS G++HRD Sbjct: 121 EFSEEKIQYLVYQMLKGLKYIHSAGVVHRD 150
>HUNK_PANTR (Q68UT7) Hormonally up-regulated neu tumor-associated kinase (EC| 2.7.11.1) Length = 714 Score = 44.3 bits (103), Expect = 3e-04 Identities = 34/123 (27%), Positives = 56/123 (45%), Gaps = 9/123 (7%) Frame = +3 Query: 252 RKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXXXXXXXXXXL------QNLCGGPNIVK 413 RK+G G +++V EG++V E L Q + PNI + Sbjct: 66 RKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIRHPNITQ 125 Query: 414 LLDIVRDQHSKTPSLIFEYI--NNTDFKVL-YPTLTDYDIRYYIYELLKALDYCHSQGIM 584 LLDI+ ++S L+ E N K+ L + + R YI +L+ A+++ H G++ Sbjct: 126 LLDILETENSY--YLVMELCPGGNLMHKIYEKKRLEESEARRYIRQLISAVEHLHRAGVV 183 Query: 585 HRD 593 HRD Sbjct: 184 HRD 186
>HUNK_MOUSE (O88866) Hormonally up-regulated neu tumor-associated kinase (EC| 2.7.11.1) (Serine/threonine-protein kinase MAK-V) Length = 714 Score = 44.3 bits (103), Expect = 3e-04 Identities = 34/123 (27%), Positives = 56/123 (45%), Gaps = 9/123 (7%) Frame = +3 Query: 252 RKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXXXXXXXXXXL------QNLCGGPNIVK 413 RK+G G +++V EG++V E L Q + PNI + Sbjct: 66 RKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIRHPNITQ 125 Query: 414 LLDIVRDQHSKTPSLIFEYI--NNTDFKVL-YPTLTDYDIRYYIYELLKALDYCHSQGIM 584 LLDI+ ++S L+ E N K+ L + + R YI +L+ A+++ H G++ Sbjct: 126 LLDILETENSY--YLVMELCPGGNLMHKIYEKKRLDEAEARRYIRQLISAVEHLHRAGVV 183 Query: 585 HRD 593 HRD Sbjct: 184 HRD 186
>HUNK_HUMAN (P57058) Hormonally up-regulated neu tumor-associated kinase (EC| 2.7.11.1) (Serine/threonine-protein kinase MAK-V) (B19) Length = 714 Score = 44.3 bits (103), Expect = 3e-04 Identities = 34/123 (27%), Positives = 56/123 (45%), Gaps = 9/123 (7%) Frame = +3 Query: 252 RKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXXXXXXXXXXL------QNLCGGPNIVK 413 RK+G G +++V EG++V E L Q + PNI + Sbjct: 66 RKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIRHPNITQ 125 Query: 414 LLDIVRDQHSKTPSLIFEYI--NNTDFKVL-YPTLTDYDIRYYIYELLKALDYCHSQGIM 584 LLDI+ ++S L+ E N K+ L + + R YI +L+ A+++ H G++ Sbjct: 126 LLDILETENSY--YLVMELCPGGNLMHKIYEKKRLEESEARRYIRQLISAVEHLHRAGVV 183 Query: 585 HRD 593 HRD Sbjct: 184 HRD 186
>MARK3_MOUSE (Q03141) MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1)| (MPK-10) (ELKL motif kinase 2) Length = 753 Score = 44.3 bits (103), Expect = 3e-04 Identities = 23/75 (30%), Positives = 41/75 (54%), Gaps = 3/75 (4%) Frame = +3 Query: 378 LQNLCGGPNIVKLLDIVRDQHSKTPSLIFEYINNT---DFKVLYPTLTDYDIRYYIYELL 548 + + PNIVKL +++ + KT LI EY + D+ V + + + + R +++ Sbjct: 106 IMKILNHPNIVKLFEVIETE--KTLYLIMEYASGGEVFDYLVAHGRMKEKEARAKFRQIV 163 Query: 549 KALDYCHSQGIMHRD 593 A+ YCH + I+HRD Sbjct: 164 SAVQYCHQKRIVHRD 178
>CDC2_PONPY (Q5RCH1) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 44.3 bits (103), Expect = 3e-04 Identities = 32/130 (24%), Positives = 58/130 (44%), Gaps = 10/130 (7%) Frame = +3 Query: 234 DDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXX----XXXXXXXXLQNLCGGP 401 +DY + K+G G Y V++G + + L P Sbjct: 2 EDYTKIEKIGEGTYGVVYKGRHKTTGQVVTMKKIRLESEEEGVPSTAIREISLLKELRHP 61 Query: 402 NIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPTLTDYD------IRYYIYELLKALDY 563 NIV L D++ Q S+ LIFE+++ D K ++ ++ Y+Y++L+ + + Sbjct: 62 NIVSLQDVLM-QDSRL-YLIFEFLS-MDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVF 118 Query: 564 CHSQGIMHRD 593 CHS+ ++HRD Sbjct: 119 CHSRRVLHRD 128
>CDC2_HUMAN (P06493) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 44.3 bits (103), Expect = 3e-04 Identities = 32/130 (24%), Positives = 58/130 (44%), Gaps = 10/130 (7%) Frame = +3 Query: 234 DDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXX----XXXXXXXXLQNLCGGP 401 +DY + K+G G Y V++G + + L P Sbjct: 2 EDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHP 61 Query: 402 NIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPTLTDYD------IRYYIYELLKALDY 563 NIV L D++ Q S+ LIFE+++ D K ++ ++ Y+Y++L+ + + Sbjct: 62 NIVSLQDVLM-QDSRL-YLIFEFLS-MDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVF 118 Query: 564 CHSQGIMHRD 593 CHS+ ++HRD Sbjct: 119 CHSRRVLHRD 128
>CDC2_BOVIN (P48734) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 44.3 bits (103), Expect = 3e-04 Identities = 32/130 (24%), Positives = 58/130 (44%), Gaps = 10/130 (7%) Frame = +3 Query: 234 DDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXX----XXXXXXXXLQNLCGGP 401 +DY + K+G G Y V++G + + L P Sbjct: 2 EDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHP 61 Query: 402 NIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPTLTDYD------IRYYIYELLKALDY 563 NIV L D++ Q S+ LIFE+++ D K ++ ++ Y+Y++L+ + + Sbjct: 62 NIVSLQDVLM-QDSRL-YLIFEFLS-MDLKKYLDSIPPGQFMDSSLVKSYLYQILQGIVF 118 Query: 564 CHSQGIMHRD 593 CHS+ ++HRD Sbjct: 119 CHSRRVLHRD 128
>MARK3_RAT (Q8VHF0) MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1)| Length = 797 Score = 44.3 bits (103), Expect = 3e-04 Identities = 23/75 (30%), Positives = 41/75 (54%), Gaps = 3/75 (4%) Frame = +3 Query: 378 LQNLCGGPNIVKLLDIVRDQHSKTPSLIFEYINNT---DFKVLYPTLTDYDIRYYIYELL 548 + + PNIVKL +++ + KT LI EY + D+ V + + + + R +++ Sbjct: 106 IMKILNHPNIVKLFEVIETE--KTLYLIMEYASGGEVFDYLVAHGRMKEKEARAKFRQIV 163 Query: 549 KALDYCHSQGIMHRD 593 A+ YCH + I+HRD Sbjct: 164 SAVQYCHQKRIVHRD 178
>CDC2_CHICK (P13863) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 44.3 bits (103), Expect = 3e-04 Identities = 31/130 (23%), Positives = 55/130 (42%), Gaps = 10/130 (7%) Frame = +3 Query: 234 DDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXX----XXXXXXXXLQNLCGGP 401 +DY + K+G G Y V++G + + L P Sbjct: 2 EDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELHHP 61 Query: 402 NIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPTLTDYD------IRYYIYELLKALDY 563 NIV L D++ LIFE+++ D K T+ ++ Y+Y++L+ + + Sbjct: 62 NIVCLQDVL--MQDARLYLIFEFLS-MDLKKYLDTIPSGQYLDRSRVKSYLYQILQGIVF 118 Query: 564 CHSQGIMHRD 593 CHS+ ++HRD Sbjct: 119 CHSRRVLHRD 128
>CRK1_LEIME (Q06309) Cell division protein kinase 2 homolog CRK1 (EC 2.7.11.23)| Length = 301 Score = 44.3 bits (103), Expect = 3e-04 Identities = 23/67 (34%), Positives = 41/67 (61%), Gaps = 3/67 (4%) Frame = +3 Query: 402 NIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPTLTDYD---IRYYIYELLKALDYCHS 572 NIVKLLD+ +H T ++FEY++ K L + D I++++ +LL+ + +CH Sbjct: 63 NIVKLLDVCHSEHRLT--IVFEYLDLDLKKYLDRENGNLDAATIQHFMRDLLRGVAFCHQ 120 Query: 573 QGIMHRD 593 + ++HRD Sbjct: 121 RSVLHRD 127
>KGS9_YEAST (P43637) Probable serine/threonine-protein kinase YGL179C (EC| 2.7.11.1) Length = 560 Score = 43.9 bits (102), Expect = 4e-04 Identities = 26/79 (32%), Positives = 39/79 (49%), Gaps = 11/79 (13%) Frame = +3 Query: 390 CGGPNIVKLLDIVRDQHSKTPSLIFEYI----------NNTDFKVLYPT-LTDYDIRYYI 536 C N+V+L +I+ D S L+ EY N + K + P+ LT R + Sbjct: 111 CHHENVVELYEILNDPESTKVYLVLEYCSRGPVKWCPENKMEIKAVGPSILTFQQSRKVV 170 Query: 537 YELLKALDYCHSQGIMHRD 593 +++ L+Y HSQGI HRD Sbjct: 171 LDVVSGLEYLHSQGITHRD 189
>TESK1_HUMAN (Q15569) Dual specificity testis-specific protein kinase 1 (EC| 2.7.12.1) (Testicular protein kinase 1) Length = 626 Score = 43.9 bits (102), Expect = 4e-04 Identities = 31/141 (21%), Positives = 56/141 (39%), Gaps = 3/141 (2%) Frame = +3 Query: 180 RPKEYWDYEALAVQWGEQDDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXXXX 359 RP Y + DD+ K+G G +SEV++ + + + Sbjct: 37 RPSSYRVLRSAVSSLARVDDFHCAEKIGAGFFSEVYKVRHRQSGQVMVLKMNKLPSNRGN 96 Query: 360 XXXXXXLQNLCGGPNIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLY--PTLTDYDIRYY 533 L N PNI++ + + H + EY+N + L P + +R + Sbjct: 97 TLREVQLMNRLRHPNILRFMGVC--VHQGQLHALTEYMNGGTLEQLLSSPEPLSWPVRLH 154 Query: 534 I-YELLKALDYCHSQGIMHRD 593 + ++ + L Y HS+G+ HRD Sbjct: 155 LALDIARGLRYLHSKGVFHRD 175
>TESK1_RAT (Q63572) Dual specificity testis-specific protein kinase 1 (EC| 2.7.12.1) (Testicular protein kinase 1) Length = 628 Score = 43.9 bits (102), Expect = 4e-04 Identities = 30/141 (21%), Positives = 57/141 (40%), Gaps = 3/141 (2%) Frame = +3 Query: 180 RPKEYWDYEALAVQWGEQDDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXXXX 359 RP Y + DD++ K+G G +SEV++ + + + Sbjct: 32 RPSSYRALRSAVSSLARVDDFDCAEKIGAGFFSEVYKVRHRQSGQVMVLKMNKLPSNRSN 91 Query: 360 XXXXXXLQNLCGGPNIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLY--PTLTDYDIRYY 533 L N PNI++ + + H + EY+N + L P + +R + Sbjct: 92 TLREVQLMNRLRHPNILRFMGVC--VHQGQLHALTEYMNGGTLEQLLSSPEPLSWPVRLH 149 Query: 534 I-YELLKALDYCHSQGIMHRD 593 + ++ + L Y H++G+ HRD Sbjct: 150 LALDIAQGLRYLHAKGVFHRD 170
>TESK1_MOUSE (O70146) Dual specificity testis-specific protein kinase 1 (EC| 2.7.12.1) (Testicular protein kinase 1) Length = 627 Score = 43.9 bits (102), Expect = 4e-04 Identities = 30/141 (21%), Positives = 57/141 (40%), Gaps = 3/141 (2%) Frame = +3 Query: 180 RPKEYWDYEALAVQWGEQDDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXXXX 359 RP Y + DD++ K+G G +SEV++ + + + Sbjct: 32 RPSSYRALRSAVSSLARVDDFDCAEKIGAGFFSEVYKVRHRQSGQVMVLKMNKLPSNRSN 91 Query: 360 XXXXXXLQNLCGGPNIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLY--PTLTDYDIRYY 533 L N PNI++ + + H + EY+N + L P + +R + Sbjct: 92 TLREVQLMNRLRHPNILRFMGVC--VHQGQLHALTEYMNGGTLEQLLSSPEPLSWPVRLH 149 Query: 534 I-YELLKALDYCHSQGIMHRD 593 + ++ + L Y H++G+ HRD Sbjct: 150 LALDIAQGLRYLHAKGVFHRD 170
>CDKL4_MOUSE (Q3TZA2) Cyclin-dependent kinase-like 4 (EC 2.7.11.22)| Length = 342 Score = 43.9 bits (102), Expect = 4e-04 Identities = 30/127 (23%), Positives = 56/127 (44%), Gaps = 7/127 (5%) Frame = +3 Query: 234 DDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXXXXXXXXXXLQ----NLCGGP 401 + YE + K+G G Y VF+ N ++ + + P Sbjct: 2 EKYEKLAKIGEGSYGVVFKCRNKSSGQVVAIKKFVESEDDRVVRKIALREIRMLKQLKHP 61 Query: 402 NIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPT---LTDYDIRYYIYELLKALDYCHS 572 N+V L+++ R + L+FEY ++T L ++D I+ +++ L+AL++CH Sbjct: 62 NLVNLIEVFR--RKRKMHLVFEYCDHTLLNELERNPNGVSDGVIKSVLWQTLQALNFCHK 119 Query: 573 QGIMHRD 593 +HRD Sbjct: 120 HNCIHRD 126
>CDC28_CANAL (P43063) Cell division control protein 28 (EC 2.7.11.22)| Length = 317 Score = 43.9 bits (102), Expect = 4e-04 Identities = 30/133 (22%), Positives = 57/133 (42%), Gaps = 11/133 (8%) Frame = +3 Query: 228 EQDDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXXXXXXXXXXLQNLC----- 392 E DY+ KVG G Y V++ ++ +N ++ + Sbjct: 3 ELSDYQRQEKVGEGTYGVVYKALDTKHNNRVVALKKIRLESEDEGVPSTAIREISLLKEM 62 Query: 393 GGPNIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPTLTD------YDIRYYIYELLKA 554 NIV+L DI+ K L+FE+++ D K ++ I+ ++ +L++ Sbjct: 63 KDDNIVRLYDIIHSDSHKL-YLVFEFLD-LDLKKYMESIPQGVGLGANMIKRFMNQLIRG 120 Query: 555 LDYCHSQGIMHRD 593 + +CHS ++HRD Sbjct: 121 IKHCHSHRVLHRD 133
>SNF1_CANGA (Q00372) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 612 Score = 43.5 bits (101), Expect = 5e-04 Identities = 26/126 (20%), Positives = 56/126 (44%), Gaps = 7/126 (5%) Frame = +3 Query: 237 DYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXXXXXXXXXXLQN-----LCGGP 401 +Y++V+ +G G + +V +V + + L P Sbjct: 38 NYQIVKTLGEGSFGKVKLAYHVTTGQKVALKIINKKVLAKSDMQGRIEREISYLRLLRHP 97 Query: 402 NIVKLLDIVRDQHSKTPSLIFEYINNT--DFKVLYPTLTDYDIRYYIYELLKALDYCHSQ 575 +I+KL D+++ + ++ EY N D+ V +++ + R + +++ A++YCH Sbjct: 98 HIIKLYDVIKSKDEII--MVIEYAGNELFDYIVQRNKMSEQEARRFFQQIISAVEYCHRH 155 Query: 576 GIMHRD 593 I+HRD Sbjct: 156 KIVHRD 161
>CC2H3_TRYBB (P54666) Cell division control protein 2 homolog 3 (EC 2.7.11.22)| Length = 311 Score = 43.5 bits (101), Expect = 5e-04 Identities = 26/68 (38%), Positives = 37/68 (54%), Gaps = 3/68 (4%) Frame = +3 Query: 399 PNIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYP---TLTDYDIRYYIYELLKALDYCH 569 PNIV LLD++ LIFEY+++ K L T ++ IY+LL+ L +CH Sbjct: 80 PNIVNLLDVICADGKLY--LIFEYVDHDLKKALEKRGGAFTGTTLKKIIYQLLEGLSFCH 137 Query: 570 SQGIMHRD 593 I+HRD Sbjct: 138 RHRIVHRD 145
>MPK2_ARATH (Q39022) Mitogen-activated protein kinase homolog 2 (EC 2.7.11.24)| (MAP kinase 2) (AtMPK2) Length = 376 Score = 43.5 bits (101), Expect = 5e-04 Identities = 30/127 (23%), Positives = 55/127 (43%), Gaps = 9/127 (7%) Frame = +3 Query: 240 YEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXXXXXXXXXX----LQNLCGGPNI 407 Y ++ +GRG Y V +N +NE L N+ Sbjct: 32 YVPIKPIGRGAYGVVCSSVNRESNERVAIKKIHNVFENRIDALRTLRELKLLRHLRHENV 91 Query: 408 VKLLDIVRDQHS---KTPSLIFEYINNTDFKVLYPT--LTDYDIRYYIYELLKALDYCHS 572 V L D++ H K L++E ++ +++ + L++ +Y++++LL+ L Y HS Sbjct: 92 VALKDVMMANHKRSFKDVYLVYELMDTDLHQIIKSSQVLSNDHCQYFLFQLLRGLKYIHS 151 Query: 573 QGIMHRD 593 I+HRD Sbjct: 152 ANILHRD 158
>MARK1_MOUSE (Q8VHJ5) Serine/threonine-protein kinase MARK1 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 1) (ELKL motif serine/threonine-protein kinase 3) Length = 795 Score = 43.5 bits (101), Expect = 5e-04 Identities = 22/75 (29%), Positives = 41/75 (54%), Gaps = 3/75 (4%) Frame = +3 Query: 378 LQNLCGGPNIVKLLDIVRDQHSKTPSLIFEYINNT---DFKVLYPTLTDYDIRYYIYELL 548 + + PNIVKL +++ + KT L+ EY + D+ V + + + + R +++ Sbjct: 110 IMKILNHPNIVKLFEVIETE--KTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIV 167 Query: 549 KALDYCHSQGIMHRD 593 A+ YCH + I+HRD Sbjct: 168 SAVQYCHQKCIVHRD 182
>MARK1_HUMAN (Q9P0L2) Serine/threonine-protein kinase MARK1 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 1) Length = 795 Score = 43.5 bits (101), Expect = 5e-04 Identities = 22/75 (29%), Positives = 41/75 (54%), Gaps = 3/75 (4%) Frame = +3 Query: 378 LQNLCGGPNIVKLLDIVRDQHSKTPSLIFEYINNT---DFKVLYPTLTDYDIRYYIYELL 548 + + PNIVKL +++ + KT L+ EY + D+ V + + + + R +++ Sbjct: 110 IMKILNHPNIVKLFEVIETE--KTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIV 167 Query: 549 KALDYCHSQGIMHRD 593 A+ YCH + I+HRD Sbjct: 168 SAVQYCHQKYIVHRD 182
>MARK1_RAT (O08678) Serine/threonine-protein kinase MARK1 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 1) Length = 793 Score = 43.5 bits (101), Expect = 5e-04 Identities = 22/75 (29%), Positives = 41/75 (54%), Gaps = 3/75 (4%) Frame = +3 Query: 378 LQNLCGGPNIVKLLDIVRDQHSKTPSLIFEYINNT---DFKVLYPTLTDYDIRYYIYELL 548 + + PNIVKL +++ + KT L+ EY + D+ V + + + + R +++ Sbjct: 110 IMKILNHPNIVKLFEVIETE--KTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIV 167 Query: 549 KALDYCHSQGIMHRD 593 A+ YCH + I+HRD Sbjct: 168 SAVQYCHQKCIVHRD 182
>CDC2_PETHY (P43290) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) (Fragment) Length = 90 Score = 43.5 bits (101), Expect = 5e-04 Identities = 22/69 (31%), Positives = 41/69 (59%), Gaps = 5/69 (7%) Frame = +3 Query: 402 NIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPTLTDYD-----IRYYIYELLKALDYC 566 NIV+L D+V + K L+FEY++ D K + ++ ++ ++Y++L+ + YC Sbjct: 21 NIVRLQDVVHSE--KRLYLVFEYLD-LDLKKHMDSSPEFSKDPRLVKMFLYQILRGIAYC 77 Query: 567 HSQGIMHRD 593 HS ++HRD Sbjct: 78 HSHRVLHRD 86
>YR436_MIMIV (Q7T6Y1) Putative serine/threonine-protein kinase R436 (EC| 2.7.11.1) Length = 276 Score = 43.5 bits (101), Expect = 5e-04 Identities = 27/80 (33%), Positives = 41/80 (51%), Gaps = 8/80 (10%) Frame = +3 Query: 378 LQNLCGGPNIVKLLDIVRDQHSKTPSLIFEYINNT----DFKVLYPTLTDYDIRYYIYEL 545 + ++ PNI+K+ D V D S +I+ YI+NT + V +TD YYI ++ Sbjct: 53 IPSILNHPNIIKIKDYVEDLDSNKMYVIYPYIDNTISLRNLPVDKFDVTDLFKLYYIIDI 112 Query: 546 L----KALDYCHSQGIMHRD 593 L A+ Y H I+HRD Sbjct: 113 LIQVVDAISYMHDNNIVHRD 132
>CD2L5_MOUSE (Q69ZA1) Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22)| (CDC2-related protein kinase 5) Length = 1511 Score = 43.5 bits (101), Expect = 5e-04 Identities = 32/159 (20%), Positives = 68/159 (42%), Gaps = 21/159 (13%) Frame = +3 Query: 180 RPK----EYWDYEALAVQWGEQ--DDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXX 341 RPK Y + + + WG++ D ++++ +G G Y +V++ + + E Sbjct: 679 RPKICGPRYGEIKEKDIDWGKRCVDKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRL 738 Query: 342 XXXXX----XXXXXXXLQNLCGGPNIVKLLDIVRDQHSKTPS--------LIFEYINNTD 485 + +I+ + +IV D+ L+FEY+++ Sbjct: 739 DNEKEGFPITAIREIKILRQLTHQSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDL 798 Query: 486 FKVLYPTLTDYD---IRYYIYELLKALDYCHSQGIMHRD 593 +L L ++ I+ ++ +L++ LDYCH + +HRD Sbjct: 799 MGLLESGLVHFNENHIKSFMRQLMEGLDYCHKKNFLHRD 837
>M4K5_HUMAN (Q9Y4K4) Mitogen-activated protein kinase kinase kinase kinase 5| (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 5) (MEK kinase kinase 5) (MEKKK 5) (Kinase homologous to SPS1/STE20) (KHS) Length = 846 Score = 43.1 bits (100), Expect = 6e-04 Identities = 33/126 (26%), Positives = 50/126 (39%), Gaps = 5/126 (3%) Frame = +3 Query: 231 QDDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXX--XXXXXXXXXXXXLQNLCGGPN 404 Q DYE+V++VG G Y +V++ NV+ E + C N Sbjct: 17 QQDYELVQRVGSGTYGDVYKARNVHTGELAAVKIIKLEPGDDFSLIQQEIFMVKECKHCN 76 Query: 405 IVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPT---LTDYDIRYYIYELLKALDYCHSQ 575 IV + + EY + +Y L++ I Y E L+ L Y H++ Sbjct: 77 IVAYFGSYLSREKLW--ICMEYCGGGSLQDIYHVTGPLSELQIAYVCRETLQGLAYLHTK 134 Query: 576 GIMHRD 593 G MHRD Sbjct: 135 GKMHRD 140
>PHO85_CANAL (Q9HGY5) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) (CaPHO85) Length = 326 Score = 43.1 bits (100), Expect = 6e-04 Identities = 29/131 (22%), Positives = 54/131 (41%), Gaps = 8/131 (6%) Frame = +3 Query: 225 GEQDDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXXXXXXXXX---XLQNLCG 395 G ++ + K+G G Y+ V++G N L Sbjct: 3 GSSSQFQQLEKLGEGTYATVYKGRNRATGALVALKEISLDSEEGTPSTAIREISLMKELD 62 Query: 396 GPNIVKLLDIVRDQHSKTPSLIFEYINNTDFKVL-----YPTLTDYDIRYYIYELLKALD 560 NIV L D++ ++ T L+FEY++ K + L ++ ++++LLK + Sbjct: 63 HENIVTLYDVIHTENKLT--LVFEYMDKDLKKYMEVHGQQSALDLKVVKSFMFQLLKGIM 120 Query: 561 YCHSQGIMHRD 593 +CH ++HRD Sbjct: 121 FCHDNRVLHRD 131
>SNF1_YEAST (P06782) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 633 Score = 43.1 bits (100), Expect = 6e-04 Identities = 19/67 (28%), Positives = 39/67 (58%), Gaps = 2/67 (2%) Frame = +3 Query: 399 PNIVKLLDIVRDQHSKTPSLIFEYINNT--DFKVLYPTLTDYDIRYYIYELLKALDYCHS 572 P+I+KL D+++ + ++ EY N D+ V +++ + R + +++ A++YCH Sbjct: 113 PHIIKLYDVIKSKDEII--MVIEYAGNELFDYIVQRDKMSEQEARRFFQQIISAVEYCHR 170 Query: 573 QGIMHRD 593 I+HRD Sbjct: 171 HKIVHRD 177
>NTF3_TOBAC (Q40517) Mitogen-activated protein kinase homolog NTF3 (EC| 2.7.11.24) (P43) Length = 372 Score = 43.1 bits (100), Expect = 6e-04 Identities = 30/127 (23%), Positives = 54/127 (42%), Gaps = 9/127 (7%) Frame = +3 Query: 240 YEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXXXXXXXXXX----LQNLCGGPNI 407 Y ++ +GRG Y V +N NE L N+ Sbjct: 32 YVPIKPIGRGAYGIVCSSVNRETNEKVAIKKINNAFENRIDALRTLRELKLLRHLRHENV 91 Query: 408 VKLLDIVRDQHS---KTPSLIFEYINNTDFKVLYP--TLTDYDIRYYIYELLKALDYCHS 572 + L D++ H K L++E ++ +++ TL++ +Y++++LL+ L Y HS Sbjct: 92 IALKDVMMPIHRRSFKDVYLVYELMDTDLHQIIKSSQTLSNDHCQYFLFQLLRGLKYLHS 151 Query: 573 QGIMHRD 593 I+HRD Sbjct: 152 ANILHRD 158
>CDC2_RAT (P39951) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 43.1 bits (100), Expect = 6e-04 Identities = 32/130 (24%), Positives = 58/130 (44%), Gaps = 10/130 (7%) Frame = +3 Query: 234 DDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXX----XXXXXXXXLQNLCGGP 401 +DY + K+G G Y V++G + + L P Sbjct: 2 EDYIKIEKIGEGTYGVVYKGRHRTTGQIVAMKKIRLESEEEGVPSTAIREISLLKELRHP 61 Query: 402 NIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPTLTDYD------IRYYIYELLKALDY 563 NIV L D++ Q S+ LIFE+++ D K ++ ++ Y+Y++L+ + + Sbjct: 62 NIVSLQDVLM-QDSRL-YLIFEFLS-MDLKKYLDSIPPGQFMDSSLVKSYLYQILQGIVF 118 Query: 564 CHSQGIMHRD 593 CHS+ ++HRD Sbjct: 119 CHSRRVLHRD 128
>MARK2_RAT (O08679) Serine/threonine-protein kinase MARK2 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 2) (ELKL Motif Kinase) (EMK1) Length = 722 Score = 43.1 bits (100), Expect = 6e-04 Identities = 22/68 (32%), Positives = 39/68 (57%), Gaps = 3/68 (4%) Frame = +3 Query: 399 PNIVKLLDIVRDQHSKTPSLIFEYINNT---DFKVLYPTLTDYDIRYYIYELLKALDYCH 569 PNIVKL +++ + KT L+ EY + D+ V + + + + R +++ A+ YCH Sbjct: 110 PNIVKLFEVIETE--KTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCH 167 Query: 570 SQGIMHRD 593 + I+HRD Sbjct: 168 QKFIVHRD 175
>MARK2_HUMAN (Q7KZI7) Serine/threonine-protein kinase MARK2 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 2) (ELKL motif kinase) (EMK1) (PAR1 homolog) Length = 788 Score = 43.1 bits (100), Expect = 6e-04 Identities = 22/68 (32%), Positives = 39/68 (57%), Gaps = 3/68 (4%) Frame = +3 Query: 399 PNIVKLLDIVRDQHSKTPSLIFEYINNT---DFKVLYPTLTDYDIRYYIYELLKALDYCH 569 PNIVKL +++ + KT L+ EY + D+ V + + + + R +++ A+ YCH Sbjct: 110 PNIVKLFEVIETE--KTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCH 167 Query: 570 SQGIMHRD 593 + I+HRD Sbjct: 168 QKFIVHRD 175
>IPL1_YEAST (P38991) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) (Increase-in-ploidy protein 1) Length = 367 Score = 43.1 bits (100), Expect = 6e-04 Identities = 33/128 (25%), Positives = 57/128 (44%), Gaps = 8/128 (6%) Frame = +3 Query: 234 DDYEVVRKVGRGKYSEVFEGINVNNN-----EXXXXXXXXXXXXXXXXXXXXXLQNLCGG 398 DD+E+ +K+G+GK+ +V+ + + + +Q Sbjct: 102 DDFELGKKLGKGKFGKVYCVRHRSTGYICALKVMEKEEIIKYNLQKQFRREVEIQTSLNH 161 Query: 399 PNIVKLLDIVRDQHSKTPSLIFEYINNTD-FKVL--YPTLTDYDIRYYIYELLKALDYCH 569 PN+ K D+ K L+ EY+ N + +K+L + D YIY++ ALDY H Sbjct: 162 PNLTKSYGYFHDE--KRVYLLMEYLVNGEMYKLLRLHGPFNDILASDYIYQIANALDYMH 219 Query: 570 SQGIMHRD 593 + I+HRD Sbjct: 220 KKNIIHRD 227
>IPL1_ASHGO (Q755C4) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 367 Score = 43.1 bits (100), Expect = 6e-04 Identities = 32/130 (24%), Positives = 56/130 (43%), Gaps = 11/130 (8%) Frame = +3 Query: 237 DYEVVRKVGRGKYSEVFEGINVNNN-----EXXXXXXXXXXXXXXXXXXXXXLQNLCGGP 401 D+E+ + +G+GK+ V+ ++ + + +Q+ P Sbjct: 108 DFEIGKVLGKGKFGRVYCVRHIESGFVCALKAMEKKDIIQYNIEKQFRREVEIQSSLRHP 167 Query: 402 NIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPTL------TDYDIRYYIYELLKALDY 563 N+ +L D+ K L+ EY+ N + LY L D YY+Y++ ALDY Sbjct: 168 NLTQLYGYFHDE--KRVYLLMEYLVNGE---LYKHLKGRSHFNDVVASYYVYQMADALDY 222 Query: 564 CHSQGIMHRD 593 H + I+HRD Sbjct: 223 MHERNILHRD 232
>M3K2_ARATH (Q9FZ36) Mitogen-activated protein kinase kinase kinase 2 (EC| 2.7.11.25) (Arabidospsis NPK1-related protein kinase 2) Length = 651 Score = 43.1 bits (100), Expect = 6e-04 Identities = 32/126 (25%), Positives = 54/126 (42%), Gaps = 14/126 (11%) Frame = +3 Query: 258 VGRGKYSEVFEGINVNNNEXXXXXXXXXXXXXXXXXXXXX-----------LQNLCGGPN 404 +GRG + V+ G+N+++ E L+NL PN Sbjct: 74 IGRGAFGTVYMGMNLDSGELLAVKQVLITSNCASKEKTQAHIQELEEEVKLLKNL-SHPN 132 Query: 405 IVKLLDIVRDQHSKTPSLIFEYINNTDFKVL---YPTLTDYDIRYYIYELLKALDYCHSQ 575 IV+ L VR+ +T +++ E++ L + + +R Y +LL L+Y H+ Sbjct: 133 IVRYLGTVRED--ETLNILLEFVPGGSISSLLEKFGAFPESVVRTYTNQLLLGLEYLHNH 190 Query: 576 GIMHRD 593 IMHRD Sbjct: 191 AIMHRD 196
>CD2L5_HUMAN (Q14004) Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22)| (CDC2-related protein kinase 5) (Cholinesterase-related cell division controller) Length = 1512 Score = 43.1 bits (100), Expect = 6e-04 Identities = 32/159 (20%), Positives = 68/159 (42%), Gaps = 21/159 (13%) Frame = +3 Query: 180 RPK----EYWDYEALAVQWGEQ--DDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXX 341 RPK Y + + + WG++ D ++++ +G G Y +V++ + + E Sbjct: 679 RPKICGPRYGETKEKDIDWGKRCVDKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRL 738 Query: 342 XXXXX----XXXXXXXLQNLCGGPNIVKLLDIVRDQHSKTPS--------LIFEYINNTD 485 + +I+ + +IV D+ L+FEY+++ Sbjct: 739 DNEKEGFPITAIREIKILRQLTHQSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDL 798 Query: 486 FKVLYPTLTDYD---IRYYIYELLKALDYCHSQGIMHRD 593 +L L ++ I+ ++ +L++ LDYCH + +HRD Sbjct: 799 MGLLESGLVHFNENHIKSFMRQLMEGLDYCHKKNFLHRD 837
>CDKL3_RAT (Q9JM01) Cyclin-dependent kinase-like 3 (EC 2.7.11.22)| (Serine/threonine protein kinase NKIATRE) Length = 593 Score = 42.7 bits (99), Expect = 8e-04 Identities = 22/67 (32%), Positives = 41/67 (61%), Gaps = 3/67 (4%) Frame = +3 Query: 402 NIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPT---LTDYDIRYYIYELLKALDYCHS 572 N+V L+++ R + K L+FE+I++T L L +R Y++++L+A++Y H+ Sbjct: 61 NLVNLIEVFRQK--KKIHLVFEFIDHTVLDELQHYCHGLESKRLRKYLFQILRAIEYLHN 118 Query: 573 QGIMHRD 593 I+HRD Sbjct: 119 NNIIHRD 125
>MPK1_ARATH (Q39021) Mitogen-activated protein kinase homolog 1 (EC 2.7.11.24)| (MAP kinase 1) (AtMPK1) Length = 370 Score = 42.7 bits (99), Expect = 8e-04 Identities = 29/127 (22%), Positives = 55/127 (43%), Gaps = 9/127 (7%) Frame = +3 Query: 240 YEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXXXXXXXXXX----LQNLCGGPNI 407 Y ++ +GRG Y V +N + NE L N+ Sbjct: 32 YMPIKPIGRGAYGVVCSSVNSDTNEKVAIKKIHNVYENRIDALRTLRELKLLRHLRHENV 91 Query: 408 VKLLDIVRDQHS---KTPSLIFEYINNTDFKVLYPT--LTDYDIRYYIYELLKALDYCHS 572 + L D++ H K L++E ++ +++ + L++ +Y++++LL+ L Y HS Sbjct: 92 IALKDVMMPIHKMSFKDVYLVYELMDTDLHQIIKSSQVLSNDHCQYFLFQLLRGLKYIHS 151 Query: 573 QGIMHRD 593 I+HRD Sbjct: 152 ANILHRD 158
>CDKL3_MOUSE (Q8BLF2) Cyclin-dependent kinase-like 3 (EC 2.7.11.22)| Length = 595 Score = 42.7 bits (99), Expect = 8e-04 Identities = 22/67 (32%), Positives = 41/67 (61%), Gaps = 3/67 (4%) Frame = +3 Query: 402 NIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPT---LTDYDIRYYIYELLKALDYCHS 572 N+V L+++ R + K L+FE+I++T L L +R Y++++L+A++Y H+ Sbjct: 61 NLVNLIEVFRQK--KKIHLVFEFIDHTVLDELQHYCHGLESKRLRKYLFQILRAIEYLHN 118 Query: 573 QGIMHRD 593 I+HRD Sbjct: 119 NNIIHRD 125
>M4K3_RAT (Q924I2) Mitogen-activated protein kinase kinase kinase kinase 3| (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 3) (MEK kinase kinase 3) (MEKKK 3) (Germinal center kinase-related protein kinase) (GLK) (Fragment) Length = 862 Score = 42.7 bits (99), Expect = 8e-04 Identities = 33/128 (25%), Positives = 54/128 (42%), Gaps = 7/128 (5%) Frame = +3 Query: 231 QDDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXX--XXXXXXXXXXXXLQNLCGGPN 404 Q+D+E+++++G G Y +V++ NVN E + C N Sbjct: 2 QEDFELIQRIGSGTYGDVYKARNVNTGELAAIKVIKLEPGEDFAVVQQEIIMMKDCKHAN 61 Query: 405 IVKLLD--IVRDQHSKTPSLIFEYINNTDFKVLYPT---LTDYDIRYYIYELLKALDYCH 569 IV + RD+ + E+ + +Y L++ I Y E L+ L Y H Sbjct: 62 IVAYFGSYLRRDK----LWICMEFCGGGSLQDIYHVTGPLSELQIAYVSRETLQGLYYLH 117 Query: 570 SQGIMHRD 593 S+G MHRD Sbjct: 118 SKGKMHRD 125
>M4K5_MOUSE (Q8BPM2) Mitogen-activated protein kinase kinase kinase kinase 5| (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 5) (MEK kinase kinase 5) (MEKKK 5) Length = 847 Score = 42.7 bits (99), Expect = 8e-04 Identities = 33/126 (26%), Positives = 50/126 (39%), Gaps = 5/126 (3%) Frame = +3 Query: 231 QDDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXX--XXXXXXXXXXXXLQNLCGGPN 404 Q DYE+V++VG G Y +V++ NV+ E + C N Sbjct: 17 QHDYELVQRVGSGTYGDVYKARNVHTGELAAVKIIKLEPGDDFSLIQQEIFMVKECKHCN 76 Query: 405 IVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPT---LTDYDIRYYIYELLKALDYCHSQ 575 IV + + EY + +Y L++ I Y E L+ L Y H++ Sbjct: 77 IVAYFGSYLSREKLW--ICMEYCGGGSLQDIYHVTGPLSEMQIAYVCRETLQGLAYLHTK 134 Query: 576 GIMHRD 593 G MHRD Sbjct: 135 GKMHRD 140
>CDC7_SCHPO (P41892) Cell division control protein 7 (EC 2.7.11.1)| Length = 1062 Score = 42.7 bits (99), Expect = 8e-04 Identities = 32/122 (26%), Positives = 53/122 (43%), Gaps = 10/122 (8%) Frame = +3 Query: 258 VGRGKYSEVFEGINVNNNEXXXXXXXXXXXXXXXXXXXXX-----LQNLCGGPNIVKLLD 422 +G+G + V+ G+N+ N E L+NL PNIVK Sbjct: 15 LGKGAFGAVYRGLNIKNGETVAVKKVKLSKMLKSDLSVIKMEIDLLKNL-DHPNIVKY-- 71 Query: 423 IVRDQHSKTPSL--IFEYINNTDFKVL---YPTLTDYDIRYYIYELLKALDYCHSQGIMH 587 R + SL I EY N + + + + + + Y +++L+ L Y H+QG++H Sbjct: 72 --RGSYQTNDSLCIILEYCENGSLRSICKNFGKIPENLVALYTFQVLQGLLYLHNQGVIH 129 Query: 588 RD 593 RD Sbjct: 130 RD 131
>MK14A_DROME (O62618) Mitogen-activated protein kinase 14A (EC 2.7.11.24) (MAP| kinase p38a) (p38 MAPK) (Dp38) (D-p38a) Length = 366 Score = 42.7 bits (99), Expect = 8e-04 Identities = 33/149 (22%), Positives = 62/149 (41%), Gaps = 13/149 (8%) Frame = +3 Query: 186 KEYWDYEALAVQWGEQDDYEVVRKVGRGKYSEVFE----GINVNNNEXXXXXXXXXXXXX 353 K+++ + +W D Y+ ++ VG G Y +V + G N++ Sbjct: 7 KKFYKLDINRTEWEIPDIYQDLQPVGSGAYGQVSKAVVRGTNMHVAIKKLARPFQSAVHA 66 Query: 354 XXXXXXXXLQNLCGGPNIVKLLDIVRDQHSKTPSL-------IFEYINNTDFK--VLYPT 506 L N++ LLDI H SL + ++ + D + Sbjct: 67 KRTYRELRLLKHMDHENVIGLLDIFHP-HPANGSLENFQQVYLVTHLMDADLNNIIRMQH 125 Query: 507 LTDYDIRYYIYELLKALDYCHSQGIMHRD 593 L+D +++ +Y++L+ L Y HS G++HRD Sbjct: 126 LSDDHVQFLVYQILRGLKYIHSAGVIHRD 154
>MARK4_MOUSE (Q8CIP4) MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1)| Length = 752 Score = 42.7 bits (99), Expect = 8e-04 Identities = 22/68 (32%), Positives = 39/68 (57%), Gaps = 3/68 (4%) Frame = +3 Query: 399 PNIVKLLDIVRDQHSKTPSLIFEYINNT---DFKVLYPTLTDYDIRYYIYELLKALDYCH 569 PNIVKL +++ + KT L+ EY + D+ V + + + + R +++ A+ YCH Sbjct: 116 PNIVKLFEVIETE--KTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCH 173 Query: 570 SQGIMHRD 593 + I+HRD Sbjct: 174 QKNIVHRD 181
>MARK4_HUMAN (Q96L34) MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase-like 1) Length = 752 Score = 42.7 bits (99), Expect = 8e-04 Identities = 22/68 (32%), Positives = 39/68 (57%), Gaps = 3/68 (4%) Frame = +3 Query: 399 PNIVKLLDIVRDQHSKTPSLIFEYINNT---DFKVLYPTLTDYDIRYYIYELLKALDYCH 569 PNIVKL +++ + KT L+ EY + D+ V + + + + R +++ A+ YCH Sbjct: 116 PNIVKLFEVIETE--KTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCH 173 Query: 570 SQGIMHRD 593 + I+HRD Sbjct: 174 QKNIVHRD 181
>CDK3_MOUSE (Q80YP0) Truncated cell division protein kinase 3 homolog| Length = 186 Score = 42.4 bits (98), Expect = 0.001 Identities = 30/128 (23%), Positives = 55/128 (42%), Gaps = 8/128 (6%) Frame = +3 Query: 234 DDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXX----XXXXXXXXLQNLCGGP 401 D ++ V K+G G Y V++ N + L P Sbjct: 2 DVFQKVEKIGEGTYGVVYKARNKVTGQLVALKKIRLDLEAEGVPSTAVREISLLKELKHP 61 Query: 402 NIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPTLTDY----DIRYYIYELLKALDYCH 569 NI+KLLD+V + K ++FE++ + + + T ++ Y+ +LL+ + +CH Sbjct: 62 NIIKLLDVVHRE--KKLYMVFEFLTQDLKRHMDSSPTSELPLPVVKSYLAQLLEGVSFCH 119 Query: 570 SQGIMHRD 593 S ++HRD Sbjct: 120 SHRVIHRD 127
>SGG_DROME (P18431) Protein kinase shaggy (EC 2.7.11.1) (Protein zeste-white| 3) Length = 1067 Score = 42.4 bits (98), Expect = 0.001 Identities = 29/74 (39%), Positives = 37/74 (50%), Gaps = 10/74 (13%) Frame = +3 Query: 402 NIVKLLDIVRDQHSKTP----SLIFEYINNTDFKVLYP------TLTDYDIRYYIYELLK 551 NIVKLL K +L+ EYI T +KV T+ IR Y+Y+L + Sbjct: 659 NIVKLLYFFYSSGEKRDEVFLNLVLEYIPETVYKVARQYAKTKQTIPINFIRLYMYQLFR 718 Query: 552 ALDYCHSQGIMHRD 593 +L Y HS GI HRD Sbjct: 719 SLAYIHSLGICHRD 732
>M3K1_ARATH (O22040) Mitogen-activated protein kinase kinase kinase 1 (EC| 2.7.11.25) (Arabidospsis NPK1-related protein kinase 1) Length = 666 Score = 42.4 bits (98), Expect = 0.001 Identities = 32/126 (25%), Positives = 52/126 (41%), Gaps = 14/126 (11%) Frame = +3 Query: 258 VGRGKYSEVFEGINVNNNEXXXXXXXXXXXXXXXXXXXXX-----------LQNLCGGPN 404 +GRG + V+ G+N+++ E L+NL PN Sbjct: 75 IGRGAFGTVYMGMNLDSGELLAVKQVLIAANFASKEKTQAHIQELEEEVKLLKNL-SHPN 133 Query: 405 IVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPTLTDYD---IRYYIYELLKALDYCHSQ 575 IV+ L VR+ T +++ E++ L + +R Y +LL L+Y H+ Sbjct: 134 IVRYLGTVREDD--TLNILLEFVPGGSISSLLEKFGPFPESVVRTYTRQLLLGLEYLHNH 191 Query: 576 GIMHRD 593 IMHRD Sbjct: 192 AIMHRD 197
>MK13_RAT (Q9WTY9) Mitogen-activated protein kinase 13 (EC 2.7.11.24)| (Stress-activated protein kinase 4) (Mitogen-activated protein kinase p38 delta) (MAP kinase p38 delta) Length = 366 Score = 42.4 bits (98), Expect = 0.001 Identities = 31/150 (20%), Positives = 58/150 (38%), Gaps = 8/150 (5%) Frame = +3 Query: 168 VNVVRPKEYWDYEALAVQWGEQDDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXX 347 ++++R + ++ + W Y VG G Y V I+ E Sbjct: 1 MSLIRKRGFYKQDINKTAWELPKTYLAPAHVGSGAYGAVCSAIDKRTGEKVAIKKLSRPF 60 Query: 348 XXXXXXXXXXLQNLC----GGPNIVKLLDIVRDQHS----KTPSLIFEYINNTDFKVLYP 503 + L N++ LLD+ S + L+ ++ K++ Sbjct: 61 QSEIFAKRAYRELLLLKHMHHENVIGLLDVYTPATSVRNFQDFYLVMPFMQTDLQKIMGM 120 Query: 504 TLTDYDIRYYIYELLKALDYCHSQGIMHRD 593 ++ ++Y +Y++LK L Y HS GI+HRD Sbjct: 121 EFSEEKVQYLVYQMLKGLKYIHSAGIVHRD 150
>CDK7_MOUSE (Q03147) Cell division protein kinase 7 (EC 2.7.11.22) (EC| 2.7.11.23) (CDK-activating kinase) (CAK) (TFIIH basal transcription factor complex kinase subunit) (39 kDa protein kinase) (P39 Mo15) (Protein-tyrosine kinase MPK-7) (CR4 protein kinas Length = 346 Score = 42.4 bits (98), Expect = 0.001 Identities = 35/130 (26%), Positives = 56/130 (43%), Gaps = 12/130 (9%) Frame = +3 Query: 240 YEVVRKVGRGKYSEVFEGINVNNNEXXXX--------XXXXXXXXXXXXXXXXXLQNLCG 395 YE + +G G+++ V++ + N N+ LQ L Sbjct: 12 YEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQEL-S 70 Query: 396 GPNIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYP----TLTDYDIRYYIYELLKALDY 563 PNI+ LLD H SL+F+++ TD +V+ LT I+ Y+ L+ L+Y Sbjct: 71 HPNIIGLLDAFG--HKSNISLVFDFME-TDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEY 127 Query: 564 CHSQGIMHRD 593 H I+HRD Sbjct: 128 LHQHWILHRD 137
>CDK7_HUMAN (P50613) Cell division protein kinase 7 (EC 2.7.11.22) (EC| 2.7.11.23) (CDK-activating kinase) (CAK) (TFIIH basal transcription factor complex kinase subunit) (39 kDa protein kinase) (P39 Mo15) (STK1) (CAK1) Length = 346 Score = 42.4 bits (98), Expect = 0.001 Identities = 35/130 (26%), Positives = 56/130 (43%), Gaps = 12/130 (9%) Frame = +3 Query: 240 YEVVRKVGRGKYSEVFEGINVNNNEXXXX--------XXXXXXXXXXXXXXXXXLQNLCG 395 YE + +G G+++ V++ + N N+ LQ L Sbjct: 12 YEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQEL-S 70 Query: 396 GPNIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYP----TLTDYDIRYYIYELLKALDY 563 PNI+ LLD H SL+F+++ TD +V+ LT I+ Y+ L+ L+Y Sbjct: 71 HPNIIGLLDAFG--HKSNISLVFDFME-TDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEY 127 Query: 564 CHSQGIMHRD 593 H I+HRD Sbjct: 128 LHQHWILHRD 137
>MPK7_ARATH (Q39027) Mitogen-activated protein kinase homolog 7 (EC 2.7.11.24)| (MAP kinase 7) (AtMPK7) Length = 368 Score = 42.0 bits (97), Expect = 0.001 Identities = 30/127 (23%), Positives = 54/127 (42%), Gaps = 9/127 (7%) Frame = +3 Query: 240 YEVVRKVGRGKYSEVFEGINVNNNEXXX----XXXXXXXXXXXXXXXXXXLQNLCGGPNI 407 Y ++ +GRG Y V IN NE L N+ Sbjct: 32 YVPIKPIGRGAYGVVCSSINRETNERVAIKKIHNVFENRVDALRTLRELKLLRHVRHENV 91 Query: 408 VKLLDIVRDQHS---KTPSLIFEYINNTDFKVL--YPTLTDYDIRYYIYELLKALDYCHS 572 + L D++ + K L++E ++ +++ +L+D +Y++++LL+ L Y HS Sbjct: 92 IALKDVMLPANRSSFKDVYLVYELMDTDLHQIIKSSQSLSDDHCKYFLFQLLRGLKYLHS 151 Query: 573 QGIMHRD 593 I+HRD Sbjct: 152 ANILHRD 158
>MAPK_PETHY (Q40884) Mitogen-activated protein kinase homolog 1 (EC 2.7.11.24)| (PMEK1) Length = 384 Score = 42.0 bits (97), Expect = 0.001 Identities = 29/127 (22%), Positives = 55/127 (43%), Gaps = 9/127 (7%) Frame = +3 Query: 240 YEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXXXXXXXXXX----LQNLCGGPNI 407 Y ++ +GRG Y V +N NE L N+ Sbjct: 32 YVPIKPIGRGAYGIVCSSVNRETNEKVAIKKINNAFENRIDALRTLRELKLLRHLRHENV 91 Query: 408 VKLLDI---VRDQHSKTPSLIFEYINNTDFKVLYP--TLTDYDIRYYIYELLKALDYCHS 572 + L D+ ++ + K L++E ++ +++ TL++ +Y++++LL+ L Y HS Sbjct: 92 IALKDVMMPIQRRSFKDVYLVYELMDTDLHQIIKSSQTLSNDHCQYFLFQLLRGLKYLHS 151 Query: 573 QGIMHRD 593 I+HRD Sbjct: 152 ANILHRD 158
>BRSK2_HUMAN (Q8IWQ3) BR serine/threonine-protein kinase 2 (EC 2.7.11.1)| (Serine/threonine-protein kinase 29) (SAD1B) Length = 736 Score = 42.0 bits (97), Expect = 0.001 Identities = 22/68 (32%), Positives = 39/68 (57%), Gaps = 3/68 (4%) Frame = +3 Query: 399 PNIVKLLDIVRDQHSKTPSLIFEYINNT---DFKVLYPTLTDYDIRYYIYELLKALDYCH 569 P+++KL D+ ++ K L+ E+++ D+ V LT + R + +++ ALD+CH Sbjct: 76 PHVLKLHDVY--ENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCH 133 Query: 570 SQGIMHRD 593 S I HRD Sbjct: 134 SHSICHRD 141
>CDC2B_ARATH (P25859) Cell division control protein 2 homolog B (EC 2.7.11.22)| (EC 2.7.11.23) Length = 309 Score = 42.0 bits (97), Expect = 0.001 Identities = 34/142 (23%), Positives = 57/142 (40%), Gaps = 22/142 (15%) Frame = +3 Query: 234 DDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXX-----XXXXXXXXLQNLCGG 398 + YE + KVG G Y +V++ + + LQ L Sbjct: 2 EKYEKLEKVGEGTYGKVYKAMEKGTGKLVALKKTRLEMDEEGIPPTALREISLLQMLSTS 61 Query: 399 PNIVKLLDIVRDQHSKTPS--------LIFEYINNTDFKVLYPT---------LTDYDIR 527 +V+LL + T S L+FEY++ TD K + L + I+ Sbjct: 62 IYVVRLLCVEHVHQPSTKSQSTKSNLYLVFEYLD-TDLKKFIDSYRKGPNPKPLEPFLIQ 120 Query: 528 YYIYELLKALDYCHSQGIMHRD 593 +++L K + +CHS G++HRD Sbjct: 121 KLMFQLCKGVAHCHSHGVLHRD 142
>CDC21_MEDSA (P24923) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| (EC 2.7.11.23) (Fragment) Length = 291 Score = 42.0 bits (97), Expect = 0.001 Identities = 32/126 (25%), Positives = 53/126 (42%), Gaps = 9/126 (7%) Frame = +3 Query: 243 EVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXX----XXXXXXXXLQNLCGGPNIV 410 E V K+G G Y V++ + NE L NIV Sbjct: 2 ENVEKIGEGTYGVVYKARDRVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQHRNIV 61 Query: 411 KLLDIVRDQHSKTPSLIFEYINNTDFKVLYPTLTDY-----DIRYYIYELLKALDYCHSQ 575 +L D+V K L+FEY++ D K + ++ ++ ++Y++L + YCHS Sbjct: 62 RLQDVVHSD--KRLYLVFEYLD-LDLKKHMDSSPEFIKDPRQVKMFLYQMLCGIAYCHSH 118 Query: 576 GIMHRD 593 ++HRD Sbjct: 119 RVLHRD 124
>CDC21_PEA (P19026) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| (EC 2.7.11.23) (p34) (Fragment) Length = 148 Score = 41.6 bits (96), Expect = 0.002 Identities = 22/69 (31%), Positives = 40/69 (57%), Gaps = 5/69 (7%) Frame = +3 Query: 402 NIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPTLTDY-----DIRYYIYELLKALDYC 566 NIV+L D+V + K L+FEY++ D K + ++ ++ ++Y++L + YC Sbjct: 46 NIVRLQDVVHSE--KRLYLVFEYLD-LDLKKHMDSSPEFVKDPRQVKMFLYQMLCGIAYC 102 Query: 567 HSQGIMHRD 593 HS ++HRD Sbjct: 103 HSHRVLHRD 111
>BRSK1_HUMAN (Q8TDC3) BR serine/threonine-protein kinase 1 (EC 2.7.11.1) (SAD1| kinase) (SAD1A) Length = 794 Score = 41.2 bits (95), Expect = 0.002 Identities = 22/68 (32%), Positives = 39/68 (57%), Gaps = 3/68 (4%) Frame = +3 Query: 399 PNIVKLLDIVRDQHSKTPSLIFEYINNT---DFKVLYPTLTDYDIRYYIYELLKALDYCH 569 P+++KL D+ ++ K L+ E+++ D+ V LT + R + +++ ALD+CH Sbjct: 107 PHVLKLHDVY--ENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALDFCH 164 Query: 570 SQGIMHRD 593 S I HRD Sbjct: 165 SYSICHRD 172
>YPC2_CAEEL (Q11179) Putative serine/threonine-protein kinase C05D10.2 in| chromosome III (EC 2.7.11.24) Length = 470 Score = 41.2 bits (95), Expect = 0.002 Identities = 27/127 (21%), Positives = 55/127 (43%), Gaps = 7/127 (5%) Frame = +3 Query: 234 DDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXXXXXXXXXX-----LQNLCGG 398 + +++ +++G+G Y V++ + + E LQ Sbjct: 11 EKFDLQKRLGKGAYGIVWKAYDKRSRETVALKKIFDAFRNPTDSQRTFREVMFLQEFGKH 70 Query: 399 PNIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLY--PTLTDYDIRYYIYELLKALDYCHS 572 PN++KL +I R + + L FE++ V+ L D +Y + +L +A+ + HS Sbjct: 71 PNVIKLYNIFRADNDRDIYLAFEFMEADLHNVIKKGSILKDVHKQYIMCQLFRAIRFLHS 130 Query: 573 QGIMHRD 593 ++HRD Sbjct: 131 GNVLHRD 137
>MK13_MOUSE (Q9Z1B7) Mitogen-activated protein kinase 13 (EC 2.7.11.24)| (Stress-activated protein kinase 4) (Mitogen-activated protein kinase p38 delta) (MAP kinase p38 delta) Length = 366 Score = 41.2 bits (95), Expect = 0.002 Identities = 31/150 (20%), Positives = 56/150 (37%), Gaps = 8/150 (5%) Frame = +3 Query: 168 VNVVRPKEYWDYEALAVQWGEQDDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXX 347 +++ R + ++ + W Y VG G Y V I+ E Sbjct: 1 MSLTRKRGFYKQDINKTAWELPKTYLAPAHVGSGAYGAVCSAIDKRTGEKVAIKKLSRPF 60 Query: 348 XXXXXXXXXXLQNLC----GGPNIVKLLDIVRDQHSKTPS----LIFEYINNTDFKVLYP 503 + L N++ LLD+ S L+ ++ K++ Sbjct: 61 QSEIFAKRAYRELLLLKHMHHENVIGLLDVFTPASSLRSFHDFYLVMPFMQTDLQKIMGM 120 Query: 504 TLTDYDIRYYIYELLKALDYCHSQGIMHRD 593 ++ ++Y +Y++LK L Y HS GI+HRD Sbjct: 121 EFSEDKVQYLVYQMLKGLKYIHSAGIVHRD 150
>MK13_PANTR (Q9N272) Mitogen-activated protein kinase 13 (EC 2.7.11.24)| (Stress-activated protein kinase 4) Length = 365 Score = 41.2 bits (95), Expect = 0.002 Identities = 20/68 (29%), Positives = 36/68 (52%), Gaps = 4/68 (5%) Frame = +3 Query: 402 NIVKLLDIVRDQHSKTPS----LIFEYINNTDFKVLYPTLTDYDIRYYIYELLKALDYCH 569 N++ LLD+ S L+ ++ K++ ++ I+Y +Y++LK L Y H Sbjct: 83 NVIGLLDVFTPASSLRNFHDFYLVMXFMQTDLQKIMXMEFSEEKIQYLVYQMLKGLKYIH 142 Query: 570 SQGIMHRD 593 S G++HRD Sbjct: 143 SAGVVHRD 150
>CDKL4_HUMAN (Q5MAI5) Cyclin-dependent kinase-like 4 (EC 2.7.11.22)| Length = 315 Score = 41.2 bits (95), Expect = 0.002 Identities = 30/127 (23%), Positives = 53/127 (41%), Gaps = 7/127 (5%) Frame = +3 Query: 234 DDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXX----XXXXXXXXLQNLCGGP 401 + YE + K G G Y VF+ N + + + P Sbjct: 2 EKYEKLAKTGEGSYGVVFKCRNKTSGQVVAVKKFVESEDDPVVKKIALREIRMLKQLKHP 61 Query: 402 NIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPT---LTDYDIRYYIYELLKALDYCHS 572 N+V L+++ R + L+FEY ++T L + D I+ +++ L+AL++CH Sbjct: 62 NLVNLIEVFR--RKRKMHLVFEYCDHTLLNELERNPNGVADGVIKSVLWQTLQALNFCHI 119 Query: 573 QGIMHRD 593 +HRD Sbjct: 120 HNCIHRD 126
>SLK_MOUSE (O54988) STE20-like serine/threonine-protein kinase (EC 2.7.11.1)| (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (mSLK) (Serine/threonine-protein kinase 2) (STE20-related kinase SMAK) (Etk4) Length = 1233 Score = 41.2 bits (95), Expect = 0.002 Identities = 34/140 (24%), Positives = 59/140 (42%), Gaps = 4/140 (2%) Frame = +3 Query: 186 KEYWDYEALAVQWGEQDDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXXXXXX 365 K+ YE + ++ +E++ ++G G + +V++ N N Sbjct: 16 KKKKQYEHVKRDLNPEEFWEIIGELGDGAFGKVYKAQNKETNVLAAAKVIDTKSEEELED 75 Query: 366 XXXXLQNL--CGGPNIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLY--PTLTDYDIRYY 533 + L C PNIVKLLD +++ + F D +L LT+ I+ Sbjct: 76 YMVEIDILASCDHPNIVKLLDAFYYENNLWILIEFCAGGAVDAVMLELERPLTESQIQVV 135 Query: 534 IYELLKALDYCHSQGIMHRD 593 + L+AL+Y H I+HRD Sbjct: 136 CKQTLEALNYLHDNKIIHRD 155
>SLK_RAT (O08815) STE20-like serine/threonine-protein kinase (EC 2.7.11.1)| (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) Length = 1206 Score = 41.2 bits (95), Expect = 0.002 Identities = 34/140 (24%), Positives = 59/140 (42%), Gaps = 4/140 (2%) Frame = +3 Query: 186 KEYWDYEALAVQWGEQDDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXXXXXX 365 K+ YE + ++ +E++ ++G G + +V++ N N Sbjct: 16 KKKKQYEHVKRDLNPEEFWEIIGELGDGAFGKVYKAQNKETNVLAAAKVIDTKSEEELED 75 Query: 366 XXXXLQNL--CGGPNIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLY--PTLTDYDIRYY 533 + L C PNIVKLLD +++ + F D +L LT+ I+ Sbjct: 76 YMVEIDILASCDHPNIVKLLDAFYYENNLWILIEFCAGGAVDAVMLELERPLTESQIQVV 135 Query: 534 IYELLKALDYCHSQGIMHRD 593 + L+AL+Y H I+HRD Sbjct: 136 CKQTLEALNYLHDNKIIHRD 155
>SPO4_SCHPO (Q9UQY9) Cell cycle protein kinase spo4 (EC 2.7.11.1)| (Sporulation-specific protein 4) Length = 429 Score = 40.8 bits (94), Expect = 0.003 Identities = 31/148 (20%), Positives = 58/148 (39%), Gaps = 27/148 (18%) Frame = +3 Query: 231 QDDYEVVRKVGRGKYSEVFEGINVN---------------------------NNEXXXXX 329 ++DY VV+ VG G +S VF+ ++ + N+ Sbjct: 37 EEDYHVVKLVGAGSFSSVFKAVDRHFDSYDNSYWISSQIEDQMPHDKTKRPKNHFVALKR 96 Query: 330 XXXXXXXXXXXXXXXXLQNLCGGPNIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPTL 509 L L G ++ ++ VR H ++ +I + +F+ Y Sbjct: 97 IYATVLPSRIQTELEMLHELRGSDCVLNMITAVR--HQDQVLIVLPFIQHAEFRDFYMKY 154 Query: 510 TDYDIRYYIYELLKALDYCHSQGIMHRD 593 + +I Y+ +LLK L + ++GI+HRD Sbjct: 155 SLPEIGAYLRDLLKGLAHIDAKGIIHRD 182
>CPK15_ARATH (P92937) CBL-interacting serine/threonine-protein kinase 15 (EC| 2.7.11.1) (Serine/threonine-protein kinase ATPK10) (SOS2-like protein kinase PKS3) (SOS-interacting protein 2) (SNF1-related kinase 3.1) Length = 421 Score = 40.8 bits (94), Expect = 0.003 Identities = 30/125 (24%), Positives = 57/125 (45%), Gaps = 7/125 (5%) Frame = +3 Query: 240 YEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXXXXXXXXX-----XLQNLCGGPN 404 YEV + +G+G +++V+ ++ + L PN Sbjct: 12 YEVGKFLGQGTFAKVYHARHLKTGDSVAIKVIDKERILKVGMTEQIKREISAMRLLRHPN 71 Query: 405 IVKLLDIVRDQHSKTPSLIFEYINNTDF--KVLYPTLTDYDIRYYIYELLKALDYCHSQG 578 IV+L +++ + SK + E++ + KV L + R Y +L++A+D+CHS+G Sbjct: 72 IVELHEVMATK-SKI-YFVMEHVKGGELFNKVSTGKLREDVARKYFQQLVRAVDFCHSRG 129 Query: 579 IMHRD 593 + HRD Sbjct: 130 VCHRD 134
>CDC28_YEAST (P00546) Cell division control protein 28 (EC 2.7.11.22)| Length = 298 Score = 40.4 bits (93), Expect = 0.004 Identities = 32/135 (23%), Positives = 55/135 (40%), Gaps = 12/135 (8%) Frame = +3 Query: 225 GEQDDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXXX-------XXXXXXXLQ 383 GE +Y+ + KVG G Y V++ +++ + L Sbjct: 3 GELANYKRLEKVGEGTYGVVYKALDLRPGQGQRVVALKKIRLESEDEGVPSTAIREISLL 62 Query: 384 NLCGGPNIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPTLTDYD-----IRYYIYELL 548 NIV+L DIV K L+FE+++ + + D ++ ++ +L Sbjct: 63 KELKDDNIVRLYDIVHSDAHKL-YLVFEFLDLDLKRYMEGIPKDQPLGADIVKKFMMQLC 121 Query: 549 KALDYCHSQGIMHRD 593 K + YCHS I+HRD Sbjct: 122 KGIAYCHSHRILHRD 136
>CDK7_RAT (P51952) Cell division protein kinase 7 (EC 2.7.11.22) (EC| 2.7.11.23) (CDK-activating kinase) (CAK) (TFIIH basal transcription factor complex kinase subunit) (39 protein kinase) (P39 Mo15) (Fragment) Length = 329 Score = 40.4 bits (93), Expect = 0.004 Identities = 25/69 (36%), Positives = 37/69 (53%), Gaps = 4/69 (5%) Frame = +3 Query: 399 PNIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYP----TLTDYDIRYYIYELLKALDYC 566 PNI+ LLD H SL+F+++ TD +V+ LT I+ Y+ L+ L+Y Sbjct: 64 PNIIGLLDAFG--HKSNISLVFDFME-TDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYL 120 Query: 567 HSQGIMHRD 593 H I+HRD Sbjct: 121 HQHWILHRD 129
>CDC2_DROME (P23572) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) Length = 297 Score = 40.4 bits (93), Expect = 0.004 Identities = 30/129 (23%), Positives = 55/129 (42%), Gaps = 9/129 (6%) Frame = +3 Query: 234 DDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXX----XXXXXXXXLQNLCGGP 401 +D+E + K+G G Y V++G N + L Sbjct: 2 EDFEKIEKIGEGTYGVVYKGRNRLTGQIVAMKKIRLESDDEGVPSTAIREISLLKELKHE 61 Query: 402 NIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPTLTDYD-----IRYYIYELLKALDYC 566 NIV L D++ +++ LIFE+++ K + D +R Y+Y++ A+ +C Sbjct: 62 NIVCLEDVLMEENRIY--LIFEFLSMDLKKYMDSLPVDKHMESELVRSYLYQITSAILFC 119 Query: 567 HSQGIMHRD 593 H + ++HRD Sbjct: 120 HRRRVLHRD 128
>SPKB_SYNY3 (P74297) Serine/threonine-protein kinase B (EC 2.7.11.1)| Length = 574 Score = 40.4 bits (93), Expect = 0.004 Identities = 22/68 (32%), Positives = 35/68 (51%), Gaps = 3/68 (4%) Frame = +3 Query: 399 PNIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYP---TLTDYDIRYYIYELLKALDYCH 569 P + +LLD D H L+ EY+ + T T+ ++ ++ E+L LDY H Sbjct: 98 PQVPRLLDYFEDDHQFY--LVQEYVKGHNLHQEVKKNGTFTEGSVKQFLTEILPILDYIH 155 Query: 570 SQGIMHRD 593 SQ ++HRD Sbjct: 156 SQKVIHRD 163
>MK12_MOUSE (O08911) Mitogen-activated protein kinase 12 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 6) (ERK-6) (Stress-activated protein kinase 3) (Mitogen-activated protein kinase p38 gamma) (MAP kinase p38 gamma) Length = 367 Score = 40.4 bits (93), Expect = 0.004 Identities = 34/145 (23%), Positives = 58/145 (40%), Gaps = 9/145 (6%) Frame = +3 Query: 186 KEYWDYEALAVQWGEQDDYEVVRKVGRGKYSEVFEGIN--VNNNEXXXXXXXXXXXXXXX 359 K ++ E W + Y+ ++ VG G Y V ++ N Sbjct: 9 KGFYRQEVTKTAWEVRAVYQDLQPVGSGAYGAVCSAVDSRTGNKVAIKKLYRPFQSELFA 68 Query: 360 XXXXXXLQNL--CGGPNIVKLLDIVRDQHSKTPSLIFEYIN---NTDFKVL--YPTLTDY 518 L+ L N++ LLD+ S F + TD L + TL++ Sbjct: 69 KRAYRELRLLKHMRHENVIGLLDVFTPDESLDDFTDFYLVMPFMGTDLGKLMKHETLSED 128 Query: 519 DIRYYIYELLKALDYCHSQGIMHRD 593 I++ +Y++LK L Y H+ G++HRD Sbjct: 129 RIQFLVYQMLKGLKYIHAAGVIHRD 153
>M3K3_ARATH (O22042) Mitogen-activated protein kinase kinase kinase 3 (EC| 2.7.11.25) (Arabidospsis NPK1-related protein kinase 3) Length = 651 Score = 40.4 bits (93), Expect = 0.004 Identities = 35/144 (24%), Positives = 59/144 (40%), Gaps = 14/144 (9%) Frame = +3 Query: 204 EALAVQWGEQDDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXXXXXXXXXX-- 377 EA +++W + + +G G + V+ G+N+++ E Sbjct: 62 EAPSIRWRKGE------LIGCGAFGRVYMGMNLDSGELLAIKQVLIAPSSASKEKTQGHI 115 Query: 378 ---------LQNLCGGPNIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPTLTDYD--- 521 L+NL PNIV+ L VR+ S +++ E++ L + Sbjct: 116 RELEEEVQLLKNL-SHPNIVRYLGTVRESDSL--NILMEFVPGGSISSLLEKFGSFPEPV 172 Query: 522 IRYYIYELLKALDYCHSQGIMHRD 593 I Y +LL L+Y H+ GIMHRD Sbjct: 173 IIMYTKQLLLGLEYLHNNGIMHRD 196
>MARK2_MOUSE (Q05512) Serine/threonine-protein kinase MARK2 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 2) (ELKL Motif Kinase) (EMK1) Length = 776 Score = 40.0 bits (92), Expect = 0.005 Identities = 21/68 (30%), Positives = 38/68 (55%), Gaps = 3/68 (4%) Frame = +3 Query: 399 PNIVKLLDIVRDQHSKTPSLIFEYINNT---DFKVLYPTLTDYDIRYYIYELLKALDYCH 569 PNIVKL +++ + KT L+ EY + D+ V + + + + R +++ + YCH Sbjct: 110 PNIVKLFEVIETE--KTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVLHVQYCH 167 Query: 570 SQGIMHRD 593 + I+HRD Sbjct: 168 QKFIVHRD 175
>SLK_HUMAN (Q9H2G2) STE20-like serine/threonine-protein kinase (EC 2.7.11.1)| (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (hSLK) (Serine/threonine-protein kinase 2) (CTCL tumor antigen se20-9) Length = 1235 Score = 40.0 bits (92), Expect = 0.005 Identities = 34/140 (24%), Positives = 58/140 (41%), Gaps = 4/140 (2%) Frame = +3 Query: 186 KEYWDYEALAVQWGEQDDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXXXXXX 365 K+ YE + +D +E++ ++G G + +V++ N + Sbjct: 16 KKKKQYEHVKRDLNPEDFWEIIGELGDGAFGKVYKAQNKETSVLAAAKVIDTKSEEELED 75 Query: 366 XXXXLQNL--CGGPNIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLY--PTLTDYDIRYY 533 + L C PNIVKLLD +++ + F D +L LT+ I+ Sbjct: 76 YMVEIDILASCDHPNIVKLLDAFYYENNLWILIEFCAGGAVDAVMLELERPLTESQIQVV 135 Query: 534 IYELLKALDYCHSQGIMHRD 593 + L AL+Y H I+HRD Sbjct: 136 CKQTLDALNYLHDNKIIHRD 155
>GSK31_SCHPO (Q9URT9) Protein kinase gsk31 (EC 2.7.11.1)| Length = 381 Score = 40.0 bits (92), Expect = 0.005 Identities = 25/78 (32%), Positives = 39/78 (50%), Gaps = 13/78 (16%) Frame = +3 Query: 399 PNIVKLLDIVRDQHSKTPS-------LIFEYINNTDFKVLY------PTLTDYDIRYYIY 539 PNI+KL+ H+ PS L+ EY+ T F + ++ + I+ Y + Sbjct: 76 PNIIKLIAFF---HTHNPSKDETHLCLLLEYMPETVFDDMRWYTRRRKSIPNLSIKLYAF 132 Query: 540 ELLKALDYCHSQGIMHRD 593 +L +AL Y HS G+ HRD Sbjct: 133 QLFRALAYLHSTGVCHRD 150
>CDKL1_HUMAN (Q00532) Cyclin-dependent kinase-like 1 (EC 2.7.11.22)| (Serine/threonine-protein kinase KKIALRE) (Protein kinase p42 KKIALRE) Length = 357 Score = 40.0 bits (92), Expect = 0.005 Identities = 28/127 (22%), Positives = 54/127 (42%), Gaps = 7/127 (5%) Frame = +3 Query: 234 DDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXX----XXXXXXXXLQNLCGGP 401 + YE + K+G G Y VF+ N + + + P Sbjct: 2 EKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQLKHP 61 Query: 402 NIVKLLDIVRDQHSKTPSLIFEYINNTDFKVL---YPTLTDYDIRYYIYELLKALDYCHS 572 N+V LL++ R + L+FEY ++T L + ++ ++ ++ L+A+++CH Sbjct: 62 NLVNLLEVFR--RKRRLHLVFEYCDHTVLHELDRYQRGVPEHLVKSITWQTLQAVNFCHK 119 Query: 573 QGIMHRD 593 +HRD Sbjct: 120 HNCIHRD 126
>CDKL5_HUMAN (O76039) Cyclin-dependent kinase-like 5 (EC 2.7.11.22)| (Serine/threonine-protein kinase 9) Length = 1030 Score = 40.0 bits (92), Expect = 0.005 Identities = 22/67 (32%), Positives = 37/67 (55%), Gaps = 3/67 (4%) Frame = +3 Query: 402 NIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPT---LTDYDIRYYIYELLKALDYCHS 572 NIV+L + R + L+FEY+ ++L + ++ YIY+L+KA+ +CH Sbjct: 71 NIVELKEAFRRRGKLY--LVFEYVEKNMLELLEEMPNGVPPEKVKSYIYQLIKAIHWCHK 128 Query: 573 QGIMHRD 593 I+HRD Sbjct: 129 NDIVHRD 135
>CDC2_MOUSE (P11440) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 40.0 bits (92), Expect = 0.005 Identities = 31/130 (23%), Positives = 58/130 (44%), Gaps = 10/130 (7%) Frame = +3 Query: 234 DDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXX----XXXXXXXXLQNLCGGP 401 +DY + K+G G Y V++G + + L P Sbjct: 2 EDYIKIEKIGEGTYGVVYKGRHRVTGQIVAMKKIRLESEEEGVPSTAIREISLLKELRHP 61 Query: 402 NIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPTLTDYD------IRYYIYELLKALDY 563 NIV L D++ Q S+ LIFE+++ D K ++ ++ Y++++L+ + + Sbjct: 62 NIVSLQDVLM-QDSRL-YLIFEFLS-MDLKKYLDSIPPGQFMDSSLVKSYLHQILQGIVF 118 Query: 564 CHSQGIMHRD 593 CHS+ ++HRD Sbjct: 119 CHSRRVLHRD 128
>PKH1_YEAST (Q03407) Serine/threonine-protein kinase PKH1 (EC 2.7.11.1)| (3-phosphoinositide-dependent protein kinase 1) Length = 766 Score = 40.0 bits (92), Expect = 0.005 Identities = 27/75 (36%), Positives = 39/75 (52%), Gaps = 3/75 (4%) Frame = +3 Query: 378 LQNLCGGPNIVKLLDIVRDQHSKTPSLIFEYINNTDFKVL---YPTLTDYDIRYYIYELL 548 LQ L G I KL +D+ S + EY + DF L Y +L + RYY +++ Sbjct: 177 LQKLNGTKGIFKLFFTFQDEASLY--FLLEYAPHGDFLGLIKKYGSLNETCARYYASQII 234 Query: 549 KALDYCHSQGIMHRD 593 A+D H+ GI+HRD Sbjct: 235 DAVDSLHNIGIIHRD 249
>SLK_CAVPO (O55092) STE20-like serine/threonine-protein kinase (EC 2.7.11.1)| (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) Length = 1231 Score = 40.0 bits (92), Expect = 0.005 Identities = 34/140 (24%), Positives = 58/140 (41%), Gaps = 4/140 (2%) Frame = +3 Query: 186 KEYWDYEALAVQWGEQDDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXXXXXX 365 K+ YE + ++ +E + ++G G + +V++ N N Sbjct: 16 KKKKQYEHVKRDLNPEEFWETIGELGDGAFGKVYKAQNKETNVLAAAKVIDTKSEEELED 75 Query: 366 XXXXLQNL--CGGPNIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLY--PTLTDYDIRYY 533 + L C PNIVKLLD +++ + F D +L LT+ I+ Sbjct: 76 YMVEIDILASCDHPNIVKLLDAFYYENNLWILIEFCAGGAVDAVMLELERPLTESQIQVV 135 Query: 534 IYELLKALDYCHSQGIMHRD 593 + L+AL+Y H I+HRD Sbjct: 136 CKQTLEALNYLHDNKIIHRD 155
>SN1L2_PONPY (Q5REX1) Serine/threonine-protein kinase SNF1-like kinase 2 (EC| 2.7.11.1) Length = 925 Score = 39.7 bits (91), Expect = 0.007 Identities = 21/68 (30%), Positives = 37/68 (54%), Gaps = 3/68 (4%) Frame = +3 Query: 399 PNIVKLLDIVRDQHSKTPSLIFEYINNT---DFKVLYPTLTDYDIRYYIYELLKALDYCH 569 P+I+KL ++ + L+ EY N D+ + L + + R +++L A+DYCH Sbjct: 77 PHIIKLYQVMETKSMLY--LVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCH 134 Query: 570 SQGIMHRD 593 + I+HRD Sbjct: 135 GRKIVHRD 142
>ROCK1_RABIT (O77819) Rho-associated protein kinase 1 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (cAMP-dependent protein kinase ROCK-I) (CePKA) (Corneal epithelial Rho-associated-Ser/Thr kinase 1) (HEB Length = 1354 Score = 39.7 bits (91), Expect = 0.007 Identities = 32/130 (24%), Positives = 55/130 (42%), Gaps = 10/130 (7%) Frame = +3 Query: 234 DDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXXXXXXXXXXLQN-----LCGG 398 +DYEVV+ +GRG + EV + + + + Sbjct: 74 EDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANS 133 Query: 399 PNIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPTLTDYDI-----RYYIYELLKALDY 563 P +V+L +D + ++ EY+ D L +++YD+ R+Y E++ ALD Sbjct: 134 PWVVQLFYAFQDD--RYLYMVMEYMPGGD---LVNLMSNYDVPEKWARFYTAEVVLALDA 188 Query: 564 CHSQGIMHRD 593 HS G +HRD Sbjct: 189 IHSMGFIHRD 198
>ROCK1_MOUSE (P70335) Rho-associated protein kinase 1 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) Length = 1354 Score = 39.7 bits (91), Expect = 0.007 Identities = 32/130 (24%), Positives = 55/130 (42%), Gaps = 10/130 (7%) Frame = +3 Query: 234 DDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXXXXXXXXXXLQN-----LCGG 398 +DYEVV+ +GRG + EV + + + + Sbjct: 74 EDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANS 133 Query: 399 PNIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPTLTDYDI-----RYYIYELLKALDY 563 P +V+L +D + ++ EY+ D L +++YD+ R+Y E++ ALD Sbjct: 134 PWVVQLFYAFQDD--RYLYMVMEYMPGGD---LVNLMSNYDVPEKWARFYTAEVVLALDA 188 Query: 564 CHSQGIMHRD 593 HS G +HRD Sbjct: 189 IHSMGFIHRD 198
>ROCK1_HUMAN (Q13464) Rho-associated protein kinase 1 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen) Length = 1354 Score = 39.7 bits (91), Expect = 0.007 Identities = 32/130 (24%), Positives = 55/130 (42%), Gaps = 10/130 (7%) Frame = +3 Query: 234 DDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXXXXXXXXXXLQN-----LCGG 398 +DYEVV+ +GRG + EV + + + + Sbjct: 74 EDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANS 133 Query: 399 PNIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPTLTDYDI-----RYYIYELLKALDY 563 P +V+L +D + ++ EY+ D L +++YD+ R+Y E++ ALD Sbjct: 134 PWVVQLFYAFQDD--RYLYMVMEYMPGGD---LVNLMSNYDVPEKWARFYTAEVVLALDA 188 Query: 564 CHSQGIMHRD 593 HS G +HRD Sbjct: 189 IHSMGFIHRD 198
>M3K2_HUMAN (Q9Y2U5) Mitogen-activated protein kinase kinase kinase 2 (EC| 2.7.11.25) (MAPK/ERK kinase kinase 2) (MEK kinase 2) (MEKK 2) Length = 619 Score = 39.7 bits (91), Expect = 0.007 Identities = 23/66 (34%), Positives = 33/66 (50%), Gaps = 3/66 (4%) Frame = +3 Query: 405 IVKLLDIVRDQHSKTPSLIFEYINNTDFK---VLYPTLTDYDIRYYIYELLKALDYCHSQ 575 IV+ +RD KT S+ EY+ K Y LT+ R Y ++L+ + Y HS Sbjct: 418 IVQYYGCLRDPQEKTLSIFMEYMPGGSIKDQLKAYGALTENVTRKYTRQILEGVHYLHSN 477 Query: 576 GIMHRD 593 I+HRD Sbjct: 478 MIVHRD 483
>ROCK2_BOVIN (Q28021) Rho-associated protein kinase 2 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 2) (p164 ROCK-2) Length = 1388 Score = 39.7 bits (91), Expect = 0.007 Identities = 32/130 (24%), Positives = 55/130 (42%), Gaps = 10/130 (7%) Frame = +3 Query: 234 DDYEVVRKVGRGKYSEVF-----EGINVNNNEXXXXXXXXXXXXXXXXXXXXXLQNLCGG 398 +DY+VV+ +GRG + EV V + + Sbjct: 90 EDYDVVKVIGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANS 149 Query: 399 PNIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPTLTDYDI-----RYYIYELLKALDY 563 P +V+L +D K ++ EY+ D L +++YD+ ++Y E++ ALD Sbjct: 150 PWVVQLFCAFQDD--KYLYMVMEYMPGGD---LVNLMSNYDVPEKWAKFYTAEVVLALDA 204 Query: 564 CHSQGIMHRD 593 HS G++HRD Sbjct: 205 IHSMGLIHRD 214
>ROCK1_RAT (Q63644) Rho-associated protein kinase 1 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (p150 RhoA-binding kinase ROK beta) (Liver regeneration-related protein LRRG199) Length = 1369 Score = 39.7 bits (91), Expect = 0.007 Identities = 32/130 (24%), Positives = 55/130 (42%), Gaps = 10/130 (7%) Frame = +3 Query: 234 DDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXXXXXXXXXXLQN-----LCGG 398 +DYEVV+ +GRG + EV + + + + Sbjct: 74 EDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANS 133 Query: 399 PNIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPTLTDYDI-----RYYIYELLKALDY 563 P +V+L +D + ++ EY+ D L +++YD+ R+Y E++ ALD Sbjct: 134 PWVVQLFYAFQDD--RYLYMVMEYMPGGD---LVNLMSNYDVPEKWARFYTAEVVLALDA 188 Query: 564 CHSQGIMHRD 593 HS G +HRD Sbjct: 189 IHSMGFIHRD 198
>LIN2_CAEEL (P54936) Protein lin-2 (Abnormal cell lineage protein 2)| Length = 961 Score = 39.7 bits (91), Expect = 0.007 Identities = 23/72 (31%), Positives = 39/72 (54%), Gaps = 7/72 (9%) Frame = +3 Query: 399 PNIVKLLDIVRDQHSKTPSLIFEYINNTD--FKVLYPT-----LTDYDIRYYIYELLKAL 557 P I +L + H + +IFE + D F+++ ++Y + +Y +LL AL Sbjct: 77 PYICRLEKTINSVHYR--HIIFENMEGNDICFEIVQRASNGFVFSEYVVSHYTRQLLDAL 134 Query: 558 DYCHSQGIMHRD 593 DYCH++ I+HRD Sbjct: 135 DYCHTRKIVHRD 146
>SN1L2_HUMAN (Q9H0K1) Serine/threonine-protein kinase SNF1-like kinase 2 (EC| 2.7.11.1) (Qin-induced kinase) Length = 926 Score = 39.7 bits (91), Expect = 0.007 Identities = 21/68 (30%), Positives = 37/68 (54%), Gaps = 3/68 (4%) Frame = +3 Query: 399 PNIVKLLDIVRDQHSKTPSLIFEYINNT---DFKVLYPTLTDYDIRYYIYELLKALDYCH 569 P+I+KL ++ + L+ EY N D+ + L + + R +++L A+DYCH Sbjct: 77 PHIIKLYQVMETKSMLY--LVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCH 134 Query: 570 SQGIMHRD 593 + I+HRD Sbjct: 135 GRKIVHRD 142
>SUR1_CAEEL (P39745) Mitogen-activated protein kinase mpk-1 (EC 2.7.11.24) (MAP| kinase sur-1) Length = 444 Score = 39.7 bits (91), Expect = 0.007 Identities = 21/68 (30%), Positives = 38/68 (55%), Gaps = 4/68 (5%) Frame = +3 Query: 402 NIVKLLDIVRDQ--HSKTPSLIFEYINNTDFKVLYPT--LTDYDIRYYIYELLKALDYCH 569 NI+ + +I+R + S I + + TD L T L++ + Y++Y++L+ L Y H Sbjct: 153 NIINIQEIIRSETVDSLKDIYIVQCLMETDLYKLLKTQKLSNDHVCYFLYQILRGLKYIH 212 Query: 570 SQGIMHRD 593 S ++HRD Sbjct: 213 SANVLHRD 220
>CDK7_XENLA (P20911) Cell division protein kinase 7 (EC 2.7.11.22) (EC| 2.7.11.23) (40 kDa protein kinase) (P40 MO15) (CDC2/CDK2,4-activating kinase) Length = 352 Score = 39.3 bits (90), Expect = 0.009 Identities = 25/69 (36%), Positives = 37/69 (53%), Gaps = 4/69 (5%) Frame = +3 Query: 399 PNIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYP----TLTDYDIRYYIYELLKALDYC 566 PNI+ LLD H SL+F+++ TD +V+ LT I+ Y+ L+ L+Y Sbjct: 78 PNIIGLLDAFG--HKSNISLVFDFME-TDLEVIIKDTSLVLTPAHIKSYMLMTLQGLEYL 134 Query: 567 HSQGIMHRD 593 H I+HRD Sbjct: 135 HHLWILHRD 143
>SN1L2_MOUSE (Q8CFH6) Serine/threonine-protein kinase SNF1-like kinase 2 (EC| 2.7.11.1) (Salt-inducible kinase 2) Length = 931 Score = 39.3 bits (90), Expect = 0.009 Identities = 20/68 (29%), Positives = 37/68 (54%), Gaps = 3/68 (4%) Frame = +3 Query: 399 PNIVKLLDIVRDQHSKTPSLIFEYINNT---DFKVLYPTLTDYDIRYYIYELLKALDYCH 569 P+I+KL ++ + L+ EY N D+ + L + + R +++L A+DYCH Sbjct: 77 PHIIKLYQVMETKSMLY--LVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCH 134 Query: 570 SQGIMHRD 593 + ++HRD Sbjct: 135 GRKVVHRD 142
>CD2L7_HUMAN (Q9NYV4) Cell division cycle 2-related protein kinase 7 (EC| 2.7.11.22) (CDC2-related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS) Length = 1490 Score = 39.3 bits (90), Expect = 0.009 Identities = 33/160 (20%), Positives = 67/160 (41%), Gaps = 22/160 (13%) Frame = +3 Query: 180 RPK----EYWDYEALAVQWGEQ--DDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXX 341 RPK Y + WG++ D ++++ +G G Y +V++ + + E Sbjct: 701 RPKICCPRYGERRQTESDWGKRCVDKFDIIGIIGEGTYGQVYKARDKDTGELVALKKVRL 760 Query: 342 XXXX-----XXXXXXXXLQNLCGGPNIVKLLDIVRDQHSKTPS--------LIFEYINNT 482 L+ L ++V + +IV D+ L+FEY+++ Sbjct: 761 DNEKEGFPITAIREIKILRQLIHR-SVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHD 819 Query: 483 DFKVLYPTLTDYD---IRYYIYELLKALDYCHSQGIMHRD 593 +L L + I+ ++ +L++ L+YCH + +HRD Sbjct: 820 LMGLLESGLVHFSEDHIKSFMKQLMEGLEYCHKKNFLHRD 859
>KJ45_SCHPO (O74526) Probable serine/threonine-protein kinase C70.05c (EC| 2.7.11.1) Length = 781 Score = 39.3 bits (90), Expect = 0.009 Identities = 25/74 (33%), Positives = 35/74 (47%), Gaps = 9/74 (12%) Frame = +3 Query: 399 PNIVKLLDIVRDQH-----SKTPSLIFEYINNTDFKVL----YPTLTDYDIRYYIYELLK 551 PN+VK D+ D H S T + ++ D L + L D I ++L+ Sbjct: 511 PNVVKSYDLCIDSHIFPLYSDTWCAVMDFCPRGDLLSLIEDRHDRLGKKDFECMIKQILR 570 Query: 552 ALDYCHSQGIMHRD 593 L+Y HSQGI HRD Sbjct: 571 GLNYIHSQGIAHRD 584
>NEK6_RAT (P59895) Serine/threonine-protein kinase Nek6 (EC 2.7.11.1)| (NimA-related protein kinase 6) Length = 313 Score = 39.3 bits (90), Expect = 0.009 Identities = 27/131 (20%), Positives = 58/131 (44%), Gaps = 12/131 (9%) Frame = +3 Query: 237 DYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXXXXXXXXXXLQNL-----CGGP 401 D+++ +K+GRG++SEV++ + + + ++ + P Sbjct: 44 DFQIEKKIGRGQFSEVYKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQLNHP 103 Query: 402 NIVKLLDIVRDQHSKTPSLIFEYINNTD-------FKVLYPTLTDYDIRYYIYELLKALD 560 NI+K LD + + +++ E + D FK + + + Y +L A++ Sbjct: 104 NIIKYLDSFIEDNEL--NIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVE 161 Query: 561 YCHSQGIMHRD 593 + HS+ +MHRD Sbjct: 162 HMHSRRVMHRD 172
>NEK6_MOUSE (Q9ES70) Serine/threonine-protein kinase Nek6 (EC 2.7.11.1)| (NimA-related protein kinase 6) Length = 313 Score = 39.3 bits (90), Expect = 0.009 Identities = 27/131 (20%), Positives = 58/131 (44%), Gaps = 12/131 (9%) Frame = +3 Query: 237 DYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXXXXXXXXXXLQNL-----CGGP 401 D+++ +K+GRG++SEV++ + + + ++ + P Sbjct: 44 DFQIEKKIGRGQFSEVYKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQLNHP 103 Query: 402 NIVKLLDIVRDQHSKTPSLIFEYINNTD-------FKVLYPTLTDYDIRYYIYELLKALD 560 NI+K LD + + +++ E + D FK + + + Y +L A++ Sbjct: 104 NIIKYLDSFIEDNEL--NIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVE 161 Query: 561 YCHSQGIMHRD 593 + HS+ +MHRD Sbjct: 162 HMHSRRVMHRD 172
>NEK6_HUMAN (Q9HC98) Serine/threonine-protein kinase Nek6 (EC 2.7.11.1)| (NimA-related protein kinase 6) (Protein kinase SID6-1512) Length = 313 Score = 39.3 bits (90), Expect = 0.009 Identities = 27/131 (20%), Positives = 58/131 (44%), Gaps = 12/131 (9%) Frame = +3 Query: 237 DYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXXXXXXXXXXLQNL-----CGGP 401 D+++ +K+GRG++SEV++ + + + ++ + P Sbjct: 44 DFQIEKKIGRGQFSEVYKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQLNHP 103 Query: 402 NIVKLLDIVRDQHSKTPSLIFEYINNTD-------FKVLYPTLTDYDIRYYIYELLKALD 560 NI+K LD + + +++ E + D FK + + + Y +L A++ Sbjct: 104 NIIKYLDSFIEDNEL--NIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVE 161 Query: 561 YCHSQGIMHRD 593 + HS+ +MHRD Sbjct: 162 HMHSRRVMHRD 172
>ERK1_CANAL (P28869) Extracellular signal-regulated kinase 1 (EC 2.7.11.24)| (ERK1) (MAP kinase 1) (MAPK 1) Length = 417 Score = 39.3 bits (90), Expect = 0.009 Identities = 33/133 (24%), Positives = 54/133 (40%), Gaps = 7/133 (5%) Frame = +3 Query: 216 VQWGEQDDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXXXXXXXXXXLQNLC- 392 V + D Y+++ VG G Y V I+ + + L Sbjct: 60 VSFNVSDHYQILEIVGEGAYGIVCSAIHKPSQQKVAIKKIEPFERSMLCLRTLRELKLLK 119 Query: 393 --GGPNIVKLLDIVR--DQHSKTPSLIFEYINNTDFKVLYPT--LTDYDIRYYIYELLKA 554 NI+ +L I R + S + + + TD + T L+D I+Y+IY+ L+A Sbjct: 120 HFNHENIISILAIQRPINYESFNEIYLIQELMETDLHRVIRTQNLSDDHIQYFIYQTLRA 179 Query: 555 LDYCHSQGIMHRD 593 L HS ++HRD Sbjct: 180 LKAMHSANVLHRD 192
>MK12_RAT (Q63538) Mitogen-activated protein kinase 12 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 6) (ERK-6) (Stress-activated protein kinase 3) (Mitogen-activated protein kinase p38 gamma) (MAP kinase p38 gamma) Length = 367 Score = 39.3 bits (90), Expect = 0.009 Identities = 33/145 (22%), Positives = 58/145 (40%), Gaps = 9/145 (6%) Frame = +3 Query: 186 KEYWDYEALAVQWGEQDDYEVVRKVGRGKYSEVFEGIN--VNNNEXXXXXXXXXXXXXXX 359 K ++ E W + Y+ ++ VG G Y V ++ N Sbjct: 9 KGFYRQEVTKTAWEVRAVYQDLQPVGSGAYGAVCSAVDSRTGNKVAIKKLYRPFQSELFA 68 Query: 360 XXXXXXLQNL--CGGPNIVKLLDIVRDQHSKTPSLIFEYIN---NTDFKVL--YPTLTDY 518 L+ L N++ LLD+ + F + TD L + TL++ Sbjct: 69 KRAYRELRLLKHMRHENVIGLLDVFTPDETLDDFTDFYLVMPFMGTDLGKLMKHETLSED 128 Query: 519 DIRYYIYELLKALDYCHSQGIMHRD 593 I++ +Y++LK L Y H+ G++HRD Sbjct: 129 RIQFLVYQMLKGLKYIHAAGVIHRD 153
>SMK1_YEAST (P41808) Sporulation-specific mitogen-activated protein kinase SMK1| (EC 2.7.11.24) (MAP kinase SMK1) Length = 388 Score = 39.3 bits (90), Expect = 0.009 Identities = 24/71 (33%), Positives = 40/71 (56%), Gaps = 4/71 (5%) Frame = +3 Query: 393 GGPNIVKLLDIVRDQHSKTPSLIF--EYINNTDFKVLYPT--LTDYDIRYYIYELLKALD 560 G NIV L+D+ S L E I+ KV++ + L+++ I+Y++Y++L L Sbjct: 96 GHKNIVNLIDLEIVTSSPYDGLYCYQELIDYDLAKVIHSSVQLSEFHIKYFLYQILCGLK 155 Query: 561 YCHSQGIMHRD 593 Y HS ++HRD Sbjct: 156 YIHSADVIHRD 166
>MPK4_ARATH (Q39024) Mitogen-activated protein kinase homolog 4 (EC 2.7.11.24)| (MAP kinase 4) (AtMPK4) Length = 376 Score = 39.3 bits (90), Expect = 0.009 Identities = 18/69 (26%), Positives = 40/69 (57%), Gaps = 5/69 (7%) Frame = +3 Query: 402 NIVKLLDIVRDQHSKTPS---LIFEYINNTDFKVLYPT--LTDYDIRYYIYELLKALDYC 566 N++ + DI++ + + +++E ++ +++ LTD R+++Y+LL+ L Y Sbjct: 101 NVIAVKDIIKPPQRENFNDVYIVYELMDTDLHQIIRSNQPLTDDHCRFFLYQLLRGLKYV 160 Query: 567 HSQGIMHRD 593 HS ++HRD Sbjct: 161 HSANVLHRD 169
>MK14B_DROME (O61443) Mitogen-activated protein kinase 14B (EC 2.7.11.24) (MAP| kinase p38b) (D-p38b) Length = 365 Score = 38.9 bits (89), Expect = 0.011 Identities = 29/150 (19%), Positives = 62/150 (41%), Gaps = 15/150 (10%) Frame = +3 Query: 189 EYWDYEALAVQWGEQDDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXXXXXXX 368 +++ + +W + Y+ ++ VG+G Y +V + + V Sbjct: 7 KFYKLDINRTEWEIPETYQNLQPVGQGAYGQVCKAV-VRGTSTKVAIKKLARPFQSAVHA 65 Query: 369 XXXLQNL-----CGGPNIVKLLDIVR--------DQHSKTPSLIFEYINNTDFKVLYPT- 506 + L N++ LLD+ DQ + + ++ + D + T Sbjct: 66 KRTYRELRLLKHMDHENVIGLLDVFHPGQPADSLDQFQQV--YMVTHLMDADLNNIIRTQ 123 Query: 507 -LTDYDIRYYIYELLKALDYCHSQGIMHRD 593 L+D +++ +Y++L+ L Y HS G++HRD Sbjct: 124 KLSDDHVQFLVYQILRGLKYIHSAGVIHRD 153
>MK14_XENLA (P47812) Mitogen-activated protein kinase 14 (EC 2.7.11.24)| (Mitogen-activated Mitogen-activated protein kinase 2) (MAP kinase 2) (MPK2) Length = 361 Score = 38.9 bits (89), Expect = 0.011 Identities = 24/75 (32%), Positives = 37/75 (49%), Gaps = 11/75 (14%) Frame = +3 Query: 402 NIVKLLDIVRDQHSKTPSLIFEYINNTDFK-----------VLYPTLTDYDIRYYIYELL 548 N++ LLD+ +P+ FE N+ V LTD +++ IY++L Sbjct: 83 NVIGLLDVF------SPAKSFEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQIL 136 Query: 549 KALDYCHSQGIMHRD 593 + L Y HS GI+HRD Sbjct: 137 RGLKYIHSAGIIHRD 151
>MPK5_ARATH (Q39025) Mitogen-activated protein kinase homolog 5 (EC 2.7.11.24)| (MAP kinase 5) (AtMPK5) Length = 376 Score = 38.9 bits (89), Expect = 0.011 Identities = 19/69 (27%), Positives = 39/69 (56%), Gaps = 5/69 (7%) Frame = +3 Query: 402 NIVKLLDIVRDQHSKT---PSLIFEYINNTDFKVLYP--TLTDYDIRYYIYELLKALDYC 566 N+V + DI+R + ++FE ++ +++ +L D +Y++Y++L+ L Y Sbjct: 101 NVVVIKDIIRPPKKEDFVDVYIVFELMDTDLHQIIRSNQSLNDDHCQYFLYQILRGLKYI 160 Query: 567 HSQGIMHRD 593 HS ++HRD Sbjct: 161 HSANVLHRD 169
>CDC15_YEAST (P27636) Cell division control protein 15 (EC 2.7.11.1)| Length = 974 Score = 38.9 bits (89), Expect = 0.011 Identities = 30/125 (24%), Positives = 53/125 (42%), Gaps = 7/125 (5%) Frame = +3 Query: 240 YEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXXXXX---XXXXXLQNLCGGPNIV 410 Y + + +GRG Y V++ IN + ++ L+NL NIV Sbjct: 25 YHLKQVIGRGSYGVVYKAINKHTDQVVAIKEVVYENDEELNDIMAEISLLKNL-NHNNIV 83 Query: 411 KLLDIVRDQHSKTPSLIFEYINNTDFKVLYPT----LTDYDIRYYIYELLKALDYCHSQG 578 K +R + ++ EY N + L L++ + + Y+ + L L Y H +G Sbjct: 84 KYHGFIRKSYELY--ILLEYCANGSLRRLISRSSTGLSENESKTYVTQTLLGLKYLHGEG 141 Query: 579 IMHRD 593 ++HRD Sbjct: 142 VIHRD 146
>MYLK_BOVIN (Q28824) Myosin light chain kinase, smooth muscle (EC 2.7.11.18)| (MLCK) [Contains: Telokin] Length = 1176 Score = 38.9 bits (89), Expect = 0.011 Identities = 30/143 (20%), Positives = 60/143 (41%), Gaps = 11/143 (7%) Frame = +3 Query: 198 DYEALAVQWGEQ--DDYEVVRKVGRGKYSEVFEGINVNNNE--XXXXXXXXXXXXXXXXX 365 DY + V ++ D Y++ ++G GK+ +VF + + Sbjct: 709 DYRTVTVNTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTGKIWAGKFFKAYSAKEKENIR 768 Query: 366 XXXXLQNLCGGPNIVKLLDIVRDQHSKTPSL-------IFEYINNTDFKVLYPTLTDYDI 524 + N P +V+ +D ++ + L +FE I + DF+ LT+ + Sbjct: 769 QEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFE-----LTEREC 823 Query: 525 RYYIYELLKALDYCHSQGIMHRD 593 Y+ ++ + ++Y H QGI+H D Sbjct: 824 IKYMKQISEGVEYIHKQGIVHLD 846
>STK6_HUMAN (O14965) Serine/threonine-protein kinase 6 (EC 2.7.11.1)| (Serine/threonine kinase 15) (Aurora/IPL1-related kinase 1) (Aurora-related kinase 1) (hARK1) (Aurora-A) (Breast-tumor-amplified kinase) Length = 403 Score = 38.9 bits (89), Expect = 0.011 Identities = 36/134 (26%), Positives = 58/134 (43%), Gaps = 9/134 (6%) Frame = +3 Query: 219 QWGEQDDYEVVRKVGRGKYSEVFEGINVNNN-----EXXXXXXXXXXXXXXXXXXXXXLQ 383 QW +D+E+ R +G+GK+ V+ + + +Q Sbjct: 127 QWA-LEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQ 185 Query: 384 NLCGGPNIVKLLDIVRDQHSKTPSLIFEYIN-NTDFKVLYPTLTDYDIRY---YIYELLK 551 + PNI++L D + LI EY T ++ L L+ +D + YI EL Sbjct: 186 SHLRHPNILRLYGYFHD--ATRVYLILEYAPLGTVYRELQK-LSKFDEQRTATYITELAN 242 Query: 552 ALDYCHSQGIMHRD 593 AL YCHS+ ++HRD Sbjct: 243 ALSYCHSKRVIHRD 256
>MYLK_MOUSE (Q6PDN3) Myosin light chain kinase, smooth muscle and non-muscle| isozymes (EC 2.7.11.18) (MLCK) [Contains: Telokin (Kinase-related protein) (KRP)] Length = 1941 Score = 38.9 bits (89), Expect = 0.011 Identities = 30/143 (20%), Positives = 60/143 (41%), Gaps = 11/143 (7%) Frame = +3 Query: 198 DYEALAVQWGEQ--DDYEVVRKVGRGKYSEVFEGINVNNNE--XXXXXXXXXXXXXXXXX 365 DY + V ++ D Y++ ++G GK+ +VF + + Sbjct: 1470 DYRTVTVNTEQKVSDVYDIEERLGSGKFGQVFRLVEKKTGKIWAGKFFKAYSAKEKDNIR 1529 Query: 366 XXXXLQNLCGGPNIVKLLDIVRDQHSKTPSL-------IFEYINNTDFKVLYPTLTDYDI 524 + N P +V+ +D ++ + L +FE I + DF+ LT+ + Sbjct: 1530 QEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFE-----LTEREC 1584 Query: 525 RYYIYELLKALDYCHSQGIMHRD 593 Y+ ++ + ++Y H QGI+H D Sbjct: 1585 IKYMRQISEGVEYIHKQGIVHLD 1607
>SN1L1_MOUSE (Q60670) Serine/threonine-protein kinase SNF1-like kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase SNF1LK) (HRT-20) (Myocardial SNF1-like kinase) Length = 779 Score = 38.9 bits (89), Expect = 0.011 Identities = 21/75 (28%), Positives = 39/75 (52%), Gaps = 3/75 (4%) Frame = +3 Query: 378 LQNLCGGPNIVKLLDIVRDQHSKTPSLIFEYINNT---DFKVLYPTLTDYDIRYYIYELL 548 L L PNI+KL ++ + ++ E+ N D+ L++ + R +++L Sbjct: 77 LMKLLNHPNIIKLYQVMETKDMLY--IVTEFAKNGEMFDYLTSNGHLSENEARQKFWQIL 134 Query: 549 KALDYCHSQGIMHRD 593 A++YCH+ I+HRD Sbjct: 135 SAVEYCHNHHIVHRD 149
>PKNB_LACLA (Q9CEF5) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 627 Score = 38.9 bits (89), Expect = 0.011 Identities = 30/130 (23%), Positives = 51/130 (39%), Gaps = 10/130 (7%) Frame = +3 Query: 234 DDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXXXXXXXXXXLQNLC------G 395 D Y +++++GRG + V++G + + Q Sbjct: 10 DRYRIIKEIGRGGMANVYQGEDTFLGDRLVAIKVLRSNFENDDIAIARFQREAFAMAELS 69 Query: 396 GPNIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLY----PTLTDYDIRYYIYELLKALDY 563 PNIV + D+ + ++ E+++ K P D I I E+L A+D Sbjct: 70 HPNIVGISDV--GEFESQQYIVMEFVDGMTLKQYINQNAPLANDEAIEI-ITEILSAMDM 126 Query: 564 CHSQGIMHRD 593 HS GI+HRD Sbjct: 127 AHSHGIIHRD 136
>MK07_HUMAN (Q13164) Mitogen-activated protein kinase 7 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 5) (ERK-5) (ERK4) (BMK1 kinase) Length = 815 Score = 38.9 bits (89), Expect = 0.011 Identities = 20/70 (28%), Positives = 41/70 (58%), Gaps = 6/70 (8%) Frame = +3 Query: 402 NIVKLLDIVRDQ----HSKTPSLIFEYINNTDFKVLYPT--LTDYDIRYYIYELLKALDY 563 NI+ + DI+R K+ ++ + + + ++++ + LT +RY++Y+LL+ L Y Sbjct: 112 NIIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKY 171 Query: 564 CHSQGIMHRD 593 HS ++HRD Sbjct: 172 MHSAQVIHRD 181
>CAKI_DROME (Q24210) Calcium/calmodulin-dependent protein kinase (EC 2.7.11.17)| (CAKI) (Peripheral plasma membrane protein CaMGUK) Length = 898 Score = 38.9 bits (89), Expect = 0.011 Identities = 30/134 (22%), Positives = 59/134 (44%), Gaps = 14/134 (10%) Frame = +3 Query: 234 DDYEVVRKVGRGKYSEVFEGINVNNNEXXXXX-------XXXXXXXXXXXXXXXXLQNLC 392 D YE+ +G+G +S V I+ +N+ + ++ Sbjct: 10 DVYELCEVIGKGPFSIVRRCIHRESNQQFAVKIVDVAKFTASPGLSTADLKREATICHML 69 Query: 393 GGPNIVKLLDIVRDQHSKTPSLIFEYINNTD--FKVLYPTLTDYDIR-----YYIYELLK 551 P+IV+LL+ + ++FE++ +D F+V+ + + +Y+ ++L+ Sbjct: 70 KHPHIVELLETYSSEGMLY--MVFEFMEGSDLCFEVVRRAVAGFVYSEAVACHYMRQILE 127 Query: 552 ALDYCHSQGIMHRD 593 AL YCH I+HRD Sbjct: 128 ALRYCHENDILHRD 141
>GSK3A_HUMAN (P49840) Glycogen synthase kinase-3 alpha (EC 2.7.11.26) (GSK-3| alpha) Length = 483 Score = 38.9 bits (89), Expect = 0.011 Identities = 18/53 (33%), Positives = 31/53 (58%), Gaps = 6/53 (11%) Frame = +3 Query: 453 SLIFEYINNTDFKVLYP------TLTDYDIRYYIYELLKALDYCHSQGIMHRD 593 +L+ EY+ T ++V T+ ++ Y+Y+L ++L Y HSQG+ HRD Sbjct: 192 NLVLEYVPETVYRVARHFTKAKLTIPILYVKVYMYQLFRSLAYIHSQGVCHRD 244
>M3K3_HUMAN (Q99759) Mitogen-activated protein kinase kinase kinase 3 (EC| 2.7.11.25) (MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3) Length = 626 Score = 38.9 bits (89), Expect = 0.011 Identities = 22/66 (33%), Positives = 34/66 (51%), Gaps = 3/66 (4%) Frame = +3 Query: 405 IVKLLDIVRDQHSKTPSLIFEYINNTDFK---VLYPTLTDYDIRYYIYELLKALDYCHSQ 575 IV+ +RD+ KT ++ EY+ K Y LT+ R Y ++L+ + Y HS Sbjct: 424 IVQYYGCLRDRAEKTLTIFMEYMPGGSVKDQLKAYGALTESVTRKYTRQILEGMSYLHSN 483 Query: 576 GIMHRD 593 I+HRD Sbjct: 484 MIVHRD 489
>CDC2B_ANTMA (Q38773) Cell division control protein 2 homolog B (EC 2.7.11.22)| (EC 2.7.11.23) (Fragment) Length = 280 Score = 38.5 bits (88), Expect = 0.015 Identities = 21/69 (30%), Positives = 39/69 (56%), Gaps = 5/69 (7%) Frame = +3 Query: 402 NIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPTLTDYD-----IRYYIYELLKALDYC 566 NIV L D+V + K L+FEY++ D K + ++ ++ ++ ++L+ + YC Sbjct: 49 NIVNLKDVVHRE--KRLYLVFEYLD-LDLKKHMDSCPEFSQDLHMVKMFLCQILRGVAYC 105 Query: 567 HSQGIMHRD 593 HS ++HRD Sbjct: 106 HSHRVLHRD 114
>CDC2H_PLAYO (Q7RM49) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 289 Score = 38.5 bits (88), Expect = 0.015 Identities = 30/129 (23%), Positives = 54/129 (41%), Gaps = 9/129 (6%) Frame = +3 Query: 234 DDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXXXXXXXXXXLQNLC-----GG 398 + Y + K+G G Y V++ N ++ E ++ + Sbjct: 2 EKYHGLEKIGEGTYGVVYKAQN-SDGESFALKKIRLEKEDEGIPSTVSIREISILKELRH 60 Query: 399 PNIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPT----LTDYDIRYYIYELLKALDYC 566 NIVKL D++ + K L+FE+++ D K L L + ++ +LL + YC Sbjct: 61 SNIVKLYDVIHAK--KRLILVFEHLDQ-DLKKLIDVCDGGLESVTAKSFLLQLLNGIAYC 117 Query: 567 HSQGIMHRD 593 H ++HRD Sbjct: 118 HEHRVLHRD 126
>IPL1_CANGA (Q6FV07) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 358 Score = 38.5 bits (88), Expect = 0.015 Identities = 35/127 (27%), Positives = 55/127 (43%), Gaps = 8/127 (6%) Frame = +3 Query: 237 DYEVVRKVGRGKYSEVFEGINVNNN-----EXXXXXXXXXXXXXXXXXXXXXLQNLCGGP 401 D+EV RK+G+GK+ +V+ + + + +Q P Sbjct: 99 DFEVGRKLGKGKFGKVYCVRHKKSGFICALKAIEKNEILQFNLLKQLKREVDIQLGMDHP 158 Query: 402 NIVKLLDIVRDQHSKTPSLIFEY-INNTDFKVLYPT--LTDYDIRYYIYELLKALDYCHS 572 NI+KL D+ K L+ E+ IN +K L D +YIY++ AL Y H Sbjct: 159 NIIKLYAHFHDE--KRVYLLMEHSINGELYKSLKNNGPFNDVLASHYIYQIADALHYMHK 216 Query: 573 QGIMHRD 593 + I+HRD Sbjct: 217 KRIIHRD 223
>PLK3_HUMAN (Q9H4B4) Serine/threonine-protein kinase PLK3 (EC 2.7.11.21)| (Polo-like kinase 3) (PLK-3) (Cytokine-inducible serine/threonine-protein kinase) (FGF-inducible kinase) (Proliferation-related kinase) Length = 646 Score = 38.5 bits (88), Expect = 0.015 Identities = 14/30 (46%), Positives = 22/30 (73%) Frame = +3 Query: 504 TLTDYDIRYYIYELLKALDYCHSQGIMHRD 593 TL + ++RYY+ ++L L Y H +GI+HRD Sbjct: 156 TLLEPEVRYYLRQILSGLKYLHQRGILHRD 185
>SNF1_CANAL (P52497) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 620 Score = 38.5 bits (88), Expect = 0.015 Identities = 17/65 (26%), Positives = 35/65 (53%) Frame = +3 Query: 399 PNIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPTLTDYDIRYYIYELLKALDYCHSQG 578 P+I+KL D+++ + + F D+ V + + + R + +++ A++YCH Sbjct: 111 PHIIKLYDVIKSKDEIIMVIEFAGKELFDYIVQRGKMPEDEARRFFQQIIAAVEYCHRHK 170 Query: 579 IMHRD 593 I+HRD Sbjct: 171 IVHRD 175
>PLK3_RAT (Q9R011) Serine/threonine-protein kinase PLK3 (EC 2.7.11.21)| (Polo-like kinase 3) (PLK-3) (Cytokine-inducible serine/threonine-protein kinase) (FGF-inducible kinase) (Fragment) Length = 615 Score = 38.5 bits (88), Expect = 0.015 Identities = 14/30 (46%), Positives = 22/30 (73%) Frame = +3 Query: 504 TLTDYDIRYYIYELLKALDYCHSQGIMHRD 593 TL + ++RYY+ ++L L Y H +GI+HRD Sbjct: 125 TLLEPEVRYYLRQILSGLKYLHQRGILHRD 154
>SNF1_CANTR (O94168) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 619 Score = 38.5 bits (88), Expect = 0.015 Identities = 17/65 (26%), Positives = 35/65 (53%) Frame = +3 Query: 399 PNIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPTLTDYDIRYYIYELLKALDYCHSQG 578 P+I+KL D+++ + + F D+ V + + + R + +++ A++YCH Sbjct: 110 PHIIKLYDVIKSKDEIIMVIEFAGKELFDYIVQRGKMPEDEARRFFQQIIAAVEYCHRHK 169 Query: 579 IMHRD 593 I+HRD Sbjct: 170 IVHRD 174
>PLK3_MOUSE (Q60806) Serine/threonine-protein kinase PLK3 (EC 2.7.11.21)| (Polo-like kinase 3) (PLK-3) (Cytokine-inducible serine/threonine-protein kinase) (FGF-inducible kinase) Length = 631 Score = 38.5 bits (88), Expect = 0.015 Identities = 14/30 (46%), Positives = 22/30 (73%) Frame = +3 Query: 504 TLTDYDIRYYIYELLKALDYCHSQGIMHRD 593 TL + ++RYY+ ++L L Y H +GI+HRD Sbjct: 157 TLLEPEVRYYLRQILSGLKYLHQRGILHRD 186
>SN1L1_RAT (Q9R1U5) Serine/threonine-protein kinase SNF1-like kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase SNF1LK) (Salt-inducible protein kinase) (Protein kinase KID2) Length = 776 Score = 38.5 bits (88), Expect = 0.015 Identities = 21/75 (28%), Positives = 39/75 (52%), Gaps = 3/75 (4%) Frame = +3 Query: 378 LQNLCGGPNIVKLLDIVRDQHSKTPSLIFEYINNT---DFKVLYPTLTDYDIRYYIYELL 548 L L PNI+KL ++ + ++ E+ N D+ L++ + R +++L Sbjct: 77 LMKLLNHPNIIKLYQVMETKDMLY--IVTEFAKNGEMFDYLTSNGHLSENEARKKFWQIL 134 Query: 549 KALDYCHSQGIMHRD 593 A++YCH+ I+HRD Sbjct: 135 SAVEYCHNHHIVHRD 149
>ROCK2_RAT (Q62868) Rho-associated protein kinase 2 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 2) (p164 ROCK-2) (RhoA-binding kinase 2) (p150 ROK-alpha) (ROKalpha) Length = 1379 Score = 38.5 bits (88), Expect = 0.015 Identities = 31/130 (23%), Positives = 55/130 (42%), Gaps = 10/130 (7%) Frame = +3 Query: 234 DDYEVVRKVGRGKYSEVF-----EGINVNNNEXXXXXXXXXXXXXXXXXXXXXLQNLCGG 398 +DY+VV+ +GRG + EV V + + Sbjct: 81 EDYDVVKVIGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANS 140 Query: 399 PNIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPTLTDYDI-----RYYIYELLKALDY 563 P +V+L +D + ++ EY+ D L +++YD+ ++Y E++ ALD Sbjct: 141 PWVVQLFCAFQDD--RYLYMVMEYMPGGD---LVNLMSNYDVPEKWAKFYTAEVVLALDA 195 Query: 564 CHSQGIMHRD 593 HS G++HRD Sbjct: 196 IHSMGLIHRD 205
>MYLK_RABIT (P29294) Myosin light chain kinase, smooth muscle (EC 2.7.11.18)| (MLCK) [Contains: Telokin] Length = 1147 Score = 38.5 bits (88), Expect = 0.015 Identities = 30/143 (20%), Positives = 60/143 (41%), Gaps = 11/143 (7%) Frame = +3 Query: 198 DYEALAVQWGEQ--DDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXXXXXX-- 365 DY + V ++ D Y++ ++G GK+ +VF + + Sbjct: 680 DYRTVTVNTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTGKIWAGKFFKAYSAKEKENIP 739 Query: 366 XXXXLQNLCGGPNIVKLLDIVRDQHSKTPSL-------IFEYINNTDFKVLYPTLTDYDI 524 + N P +V+ +D ++ + L +FE I + DF+ LT+ + Sbjct: 740 AEIGIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFE-----LTEREC 794 Query: 525 RYYIYELLKALDYCHSQGIMHRD 593 Y+ ++ + ++Y H QGI+H D Sbjct: 795 IKYMRQISEGVEYIHKQGIVHLD 817
>MYLK_HUMAN (Q15746) Myosin light chain kinase, smooth muscle and non-muscle| isozymes (EC 2.7.11.18) (MLCK) [Contains: Telokin (Kinase-related protein) (KRP)] Length = 1914 Score = 38.5 bits (88), Expect = 0.015 Identities = 29/143 (20%), Positives = 60/143 (41%), Gaps = 11/143 (7%) Frame = +3 Query: 198 DYEALAVQWGEQ--DDYEVVRKVGRGKYSEVFEGINVNNNE--XXXXXXXXXXXXXXXXX 365 DY + + ++ D Y++ ++G GK+ +VF + + Sbjct: 1448 DYRTVTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIR 1507 Query: 366 XXXXLQNLCGGPNIVKLLDIVRDQHSKTPSL-------IFEYINNTDFKVLYPTLTDYDI 524 + N P +V+ +D ++ + L +FE I + DF+ LT+ + Sbjct: 1508 QEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFE-----LTEREC 1562 Query: 525 RYYIYELLKALDYCHSQGIMHRD 593 Y+ ++ + ++Y H QGI+H D Sbjct: 1563 IKYMRQISEGVEYIHKQGIVHLD 1585
>ROCK2_MOUSE (P70336) Rho-associated protein kinase 2 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 2) (p164 ROCK-2) Length = 1388 Score = 38.5 bits (88), Expect = 0.015 Identities = 31/130 (23%), Positives = 55/130 (42%), Gaps = 10/130 (7%) Frame = +3 Query: 234 DDYEVVRKVGRGKYSEVF-----EGINVNNNEXXXXXXXXXXXXXXXXXXXXXLQNLCGG 398 +DY+VV+ +GRG + EV V + + Sbjct: 90 EDYDVVKVIGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANS 149 Query: 399 PNIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPTLTDYDI-----RYYIYELLKALDY 563 P +V+L +D + ++ EY+ D L +++YD+ ++Y E++ ALD Sbjct: 150 PWVVQLFCAFQDD--RYLYMVMEYMPGGD---LVNLMSNYDVPEKWAKFYTAEVVLALDA 204 Query: 564 CHSQGIMHRD 593 HS G++HRD Sbjct: 205 IHSMGLIHRD 214
>ROCK2_HUMAN (O75116) Rho-associated protein kinase 2 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2) Length = 1388 Score = 38.5 bits (88), Expect = 0.015 Identities = 31/130 (23%), Positives = 55/130 (42%), Gaps = 10/130 (7%) Frame = +3 Query: 234 DDYEVVRKVGRGKYSEVF-----EGINVNNNEXXXXXXXXXXXXXXXXXXXXXLQNLCGG 398 +DY+VV+ +GRG + EV V + + Sbjct: 90 EDYDVVKVIGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANS 149 Query: 399 PNIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPTLTDYDI-----RYYIYELLKALDY 563 P +V+L +D + ++ EY+ D L +++YD+ ++Y E++ ALD Sbjct: 150 PWVVQLFYAFQDD--RYLYMVMEYMPGGD---LVNLMSNYDVPEKWAKFYTAEVVLALDA 204 Query: 564 CHSQGIMHRD 593 HS G++HRD Sbjct: 205 IHSMGLIHRD 214
>BYR2_SCHPO (P28829) Protein kinase byr2 (EC 2.7.11.25) (Protein kinase ste8)| (MAPK kinase kinase) (MAPKKK) Length = 659 Score = 38.5 bits (88), Expect = 0.015 Identities = 27/125 (21%), Positives = 51/125 (40%), Gaps = 13/125 (10%) Frame = +3 Query: 258 VGRGKYSEVFEGINVNNNEXXXXXXXXXXXXXXXXXXXXXLQNLCGGPNIVKLLDIVRDQ 437 +G G + +V+ G+N ++ E L + G + LL + + Sbjct: 400 IGSGSFGQVYLGMNASSGELMAVKQVILDSVSESKDRHAKLLDALAGE--IALLQELSHE 457 Query: 438 H----------SKTPSLIFEYINN---TDFKVLYPTLTDYDIRYYIYELLKALDYCHSQG 578 H S ++ EY+ +Y + + ++ +I + LK L+Y HS+G Sbjct: 458 HIVQYLGSNLNSDHLNIFLEYVPGGSVAGLLTMYGSFEETLVKNFIKQTLKGLEYLHSRG 517 Query: 579 IMHRD 593 I+HRD Sbjct: 518 IVHRD 522
>CDC2H_PLAFK (Q07785) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (PfPK5) Length = 288 Score = 38.5 bits (88), Expect = 0.015 Identities = 22/68 (32%), Positives = 37/68 (54%), Gaps = 4/68 (5%) Frame = +3 Query: 402 NIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPT----LTDYDIRYYIYELLKALDYCH 569 NIVKL D++ + K L+FE+++ D K L L + ++ +LL + YCH Sbjct: 61 NIVKLYDVIHTK--KRLVLVFEHLDQ-DLKKLLDVCEGGLESVTAKSFLLQLLNGIAYCH 117 Query: 570 SQGIMHRD 593 + ++HRD Sbjct: 118 DRRVLHRD 125
>CDC2H_PLAF7 (P61075) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 288 Score = 38.5 bits (88), Expect = 0.015 Identities = 22/68 (32%), Positives = 37/68 (54%), Gaps = 4/68 (5%) Frame = +3 Query: 402 NIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPT----LTDYDIRYYIYELLKALDYCH 569 NIVKL D++ + K L+FE+++ D K L L + ++ +LL + YCH Sbjct: 61 NIVKLYDVIHTK--KRLVLVFEHLDQ-DLKKLLDVCEGGLESVTAKSFLLQLLNGIAYCH 117 Query: 570 SQGIMHRD 593 + ++HRD Sbjct: 118 DRRVLHRD 125
>MAPK_FUSSO (Q00859) Mitogen-activated protein kinase (EC 2.7.11.24) (FsMAPK)| Length = 355 Score = 38.1 bits (87), Expect = 0.019 Identities = 23/68 (33%), Positives = 36/68 (52%), Gaps = 4/68 (5%) Frame = +3 Query: 402 NIVKLLDIV--RDQHSKTPSLIFEYINNTDFKVLYPT--LTDYDIRYYIYELLKALDYCH 569 NI+ +LDI R+ S + + + TD T L+D +Y+IY+ L+AL H Sbjct: 80 NIISILDIQKPRNYESFNEVYLIQELMETDMHRAIRTQDLSDDHCQYFIYQTLRALKAMH 139 Query: 570 SQGIMHRD 593 S ++HRD Sbjct: 140 SANVLHRD 147
>CDC2H_PLAVI (Q9XZD6) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (Pvcrk2) Length = 288 Score = 38.1 bits (87), Expect = 0.019 Identities = 22/68 (32%), Positives = 36/68 (52%), Gaps = 4/68 (5%) Frame = +3 Query: 402 NIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPT----LTDYDIRYYIYELLKALDYCH 569 NIVKL D++ + K L+FE+++ D K L L + ++ +LL + YCH Sbjct: 61 NIVKLYDVIHTK--KRLILVFEHLDQ-DLKKLLDVCDGGLESVTAKSFLLQLLSGIAYCH 117 Query: 570 SQGIMHRD 593 ++HRD Sbjct: 118 EHRVLHRD 125
>CDC2H_PLAKH (O96821) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 288 Score = 38.1 bits (87), Expect = 0.019 Identities = 22/68 (32%), Positives = 36/68 (52%), Gaps = 4/68 (5%) Frame = +3 Query: 402 NIVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPT----LTDYDIRYYIYELLKALDYCH 569 NIVKL D++ + K L+FE+++ D K L L + ++ +LL + YCH Sbjct: 61 NIVKLYDVIHTK--KRLILVFEHLDQ-DLKKLLDVCDGGLESVTAKSFLLQLLSGIAYCH 117 Query: 570 SQGIMHRD 593 ++HRD Sbjct: 118 EHRVLHRD 125
>CDC2H_PLACH (Q4Y4B1) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 288 Score = 38.1 bits (87), Expect = 0.019 Identities = 29/127 (22%), Positives = 50/127 (39%), Gaps = 7/127 (5%) Frame = +3 Query: 234 DDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXX---XXXXXXXXLQNLCGGPN 404 + Y + K+G G Y V++ N + + N Sbjct: 2 EKYHGLEKIGEGTYGVVYKAQNSDGESFALKKIRLEKEDEGIPSTAIREISILKELRHSN 61 Query: 405 IVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPT----LTDYDIRYYIYELLKALDYCHS 572 IVKL D++ + K L+FE+++ D K L L + ++ +LL + YCH Sbjct: 62 IVKLYDVIHAK--KRLILVFEHLDQ-DLKKLIDVCDGGLESVTAKSFLLQLLNGIAYCHE 118 Query: 573 QGIMHRD 593 ++HRD Sbjct: 119 HRVLHRD 125
>CDC2H_PLABA (Q4Z6R1) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 288 Score = 38.1 bits (87), Expect = 0.019 Identities = 29/127 (22%), Positives = 50/127 (39%), Gaps = 7/127 (5%) Frame = +3 Query: 234 DDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXX---XXXXXXXXLQNLCGGPN 404 + Y + K+G G Y V++ N + + N Sbjct: 2 EKYHGLEKIGEGTYGVVYKAQNSDGESFALKKIRLEKEDEGIPSTAIREISILKELRHSN 61 Query: 405 IVKLLDIVRDQHSKTPSLIFEYINNTDFKVLYPT----LTDYDIRYYIYELLKALDYCHS 572 IVKL D++ + K L+FE+++ D K L L + ++ +LL + YCH Sbjct: 62 IVKLYDVIHAK--KRLILVFEHLDQ-DLKKLIDVCDGGLESVTAKSFLLQLLNGIAYCHE 118 Query: 573 QGIMHRD 593 ++HRD Sbjct: 119 HRVLHRD 125
>CSKP_MOUSE (O70589) Peripheral plasma membrane protein CASK (EC 2.7.11.1)| (Calcium/calmodulin-dependent serine protein kinase) Length = 924 Score = 38.1 bits (87), Expect = 0.019 Identities = 30/136 (22%), Positives = 53/136 (38%), Gaps = 15/136 (11%) Frame = +3 Query: 231 QDDYEVVRKVGRGKYSEVFEGINVNNNEXXXXXXXXXXXXXXXXXXXX-------XLQNL 389 +D YE+ +G+G +S V IN + + ++ Sbjct: 9 EDVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASICHM 68 Query: 390 CGGPNIVKLLDIVRD--------QHSKTPSLIFEYINNTDFKVLYPTLTDYDIRYYIYEL 545 P+IV+LL+ + L FE + D +Y ++ +Y+ ++ Sbjct: 69 LKHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVY---SEAVASHYMRQI 125 Query: 546 LKALDYCHSQGIMHRD 593 L+AL YCH I+HRD Sbjct: 126 LEALRYCHDNNIIHRD 141 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 78,140,424 Number of Sequences: 219361 Number of extensions: 1467238 Number of successful extensions: 7180 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 6156 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 6956 length of database: 80,573,946 effective HSP length: 106 effective length of database: 57,321,680 effective search space used: 5216272880 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
