Clone Name | bart17a03 |
---|---|
Clone Library Name | barley_pub |
>SNX7_MOUSE (Q9CY18) Sorting nexin-7| Length = 387 Score = 103 bits (257), Expect = 3e-22 Identities = 54/120 (45%), Positives = 77/120 (64%), Gaps = 2/120 (1%) Frame = +2 Query: 173 LSICVTDPVKMGTGVQSYISYRVITKTNLPEFEGAEKIVIRRYSDFEWLHDRLAEKYKGI 352 L I V P T ++++I+YR++TKT+ EF+ +E V RRY DF WL +L E + + Sbjct: 32 LFITVDAPESHVTTIETFITYRIVTKTSRGEFDSSEFEVRRRYQDFLWLKGKLEEAHPTL 91 Query: 353 FIPPLPEKNAVEKF--RFSKEFIELRRQALDLFINRLASHPELKQSEDLRTFLQADEEKM 526 IPPLPEK V+ RF+ +FIE RR+AL F+NR+A HP L +ED + FL A E++ Sbjct: 92 IIPPLPEKFIVKGMVERFNDDFIETRRKALHKFLNRIADHPTLTFNEDFKVFLTAQAEEL 151
>SNX7_MACFA (Q4R5U9) Sorting nexin-7| Length = 387 Score = 102 bits (254), Expect = 7e-22 Identities = 54/115 (46%), Positives = 75/115 (65%), Gaps = 2/115 (1%) Frame = +2 Query: 173 LSICVTDPVKMGTGVQSYISYRVITKTNLPEFEGAEKIVIRRYSDFEWLHDRLAEKYKGI 352 L I V +P T ++++I+YR+ITKT+ EF+ +E V RRY DF WL +L E + + Sbjct: 32 LFITVDEPESHVTTIETFITYRIITKTSRGEFDSSEFEVRRRYQDFLWLKGKLEEAHPTL 91 Query: 353 FIPPLPEKNAVEKF--RFSKEFIELRRQALDLFINRLASHPELKQSEDLRTFLQA 511 IPPLPEK V+ RF+ +FIE RR+AL F+NR+A HP L +ED + FL A Sbjct: 92 IIPPLPEKFIVKGMVERFNDDFIETRRKALHKFLNRIADHPTLTFNEDFKIFLTA 146
>SNX7_HUMAN (Q9UNH6) Sorting nexin-7| Length = 387 Score = 102 bits (254), Expect = 7e-22 Identities = 54/115 (46%), Positives = 75/115 (65%), Gaps = 2/115 (1%) Frame = +2 Query: 173 LSICVTDPVKMGTGVQSYISYRVITKTNLPEFEGAEKIVIRRYSDFEWLHDRLAEKYKGI 352 L I V +P T ++++I+YR+ITKT+ EF+ +E V RRY DF WL +L E + + Sbjct: 32 LFITVDEPESHVTTIETFITYRIITKTSRGEFDSSEFEVRRRYQDFLWLKGKLEEAHPTL 91 Query: 353 FIPPLPEKNAVEKF--RFSKEFIELRRQALDLFINRLASHPELKQSEDLRTFLQA 511 IPPLPEK V+ RF+ +FIE RR+AL F+NR+A HP L +ED + FL A Sbjct: 92 IIPPLPEKFIVKGMVERFNDDFIETRRKALHKFLNRIADHPTLTFNEDFKIFLTA 146
>SNX2_MOUSE (Q9CWK8) Sorting nexin-2| Length = 519 Score = 99.0 bits (245), Expect = 8e-21 Identities = 55/125 (44%), Positives = 76/125 (60%), Gaps = 10/125 (8%) Frame = +2 Query: 173 LSICVTDPVKMGTGVQSYISYRVITKTNLPEFEGAEKIVIRRYSDFEWLHDRLAEKY--K 346 + I V+DP K+G G+ +Y++YRV TKT+L F +E V RR+SDF LH +LA KY Sbjct: 142 IEIGVSDPEKVGDGMNAYMAYRVTTKTSLSMFSKSEFSVKRRFSDFLGLHSKLASKYLHV 201 Query: 347 GIFIPPLPEKNAV--------EKFRFSKEFIELRRQALDLFINRLASHPELKQSEDLRTF 502 G +PP PEK+ V ++ S EF+E RR AL+ ++ R HP L Q DLR F Sbjct: 202 GYIVPPAPEKSIVGMTKVKVGKEDSSSTEFVEKRRAALERYLQRTVKHPTLLQDPDLRQF 261 Query: 503 LQADE 517 L++ E Sbjct: 262 LESSE 266
>SNX2_HUMAN (O60749) Sorting nexin-2| Length = 519 Score = 99.0 bits (245), Expect = 8e-21 Identities = 55/125 (44%), Positives = 76/125 (60%), Gaps = 10/125 (8%) Frame = +2 Query: 173 LSICVTDPVKMGTGVQSYISYRVITKTNLPEFEGAEKIVIRRYSDFEWLHDRLAEKY--K 346 + I V+DP K+G G+ +Y++YRV TKT+L F +E V RR+SDF LH +LA KY Sbjct: 142 IEIGVSDPEKVGDGMNAYMAYRVTTKTSLSMFSKSEFSVKRRFSDFLGLHSKLASKYLHV 201 Query: 347 GIFIPPLPEKNAV--------EKFRFSKEFIELRRQALDLFINRLASHPELKQSEDLRTF 502 G +PP PEK+ V ++ S EF+E RR AL+ ++ R HP L Q DLR F Sbjct: 202 GYIVPPAPEKSIVGMTKVKVGKEDSSSTEFVEKRRAALERYLQRTVKHPTLLQDPDLRQF 261 Query: 503 LQADE 517 L++ E Sbjct: 262 LESSE 266
>SNX1_RAT (Q99N27) Sorting nexin-1| Length = 522 Score = 97.8 bits (242), Expect = 2e-20 Identities = 48/125 (38%), Positives = 81/125 (64%), Gaps = 10/125 (8%) Frame = +2 Query: 173 LSICVTDPVKMGTGVQSYISYRVITKTNLPEFEGAEKIVIRRYSDFEWLHDRLAEKY--K 346 L++ +TDP K+G G+ +Y++Y+V T+T+LP F + V RR+SDF L+++L+EK+ Sbjct: 145 LTVGITDPEKIGDGMNAYVAYKVTTQTSLPMFRSRQFAVKRRFSDFLGLYEKLSEKHSQN 204 Query: 347 GIFIPPLPEKNAV--------EKFRFSKEFIELRRQALDLFINRLASHPELKQSEDLRTF 502 G +PP PEK+ + ++ S EF+E RR AL+ ++ R+ +HP + Q D+R F Sbjct: 205 GFIVPPPPEKSLIGMTKVKVGKEDSSSAEFLEKRRAALERYLQRIVNHPTMLQDPDVREF 264 Query: 503 LQADE 517 L+ +E Sbjct: 265 LEKEE 269
>SNX1_MOUSE (Q9WV80) Sorting nexin-1| Length = 522 Score = 97.8 bits (242), Expect = 2e-20 Identities = 48/125 (38%), Positives = 81/125 (64%), Gaps = 10/125 (8%) Frame = +2 Query: 173 LSICVTDPVKMGTGVQSYISYRVITKTNLPEFEGAEKIVIRRYSDFEWLHDRLAEKY--K 346 L++ +TDP K+G G+ +Y++Y+V T+T+LP F + V RR+SDF L+++L+EK+ Sbjct: 145 LTVGITDPEKIGDGMNAYVAYKVTTQTSLPMFRSRQFAVKRRFSDFLGLYEKLSEKHSQN 204 Query: 347 GIFIPPLPEKNAV--------EKFRFSKEFIELRRQALDLFINRLASHPELKQSEDLRTF 502 G +PP PEK+ + ++ S EF+E RR AL+ ++ R+ +HP + Q D+R F Sbjct: 205 GFIVPPPPEKSLIGMTKVKVGKEDSSSAEFLEKRRAALERYLQRIVNHPTMLQDPDVREF 264 Query: 503 LQADE 517 L+ +E Sbjct: 265 LEKEE 269
>SNX1_HUMAN (Q13596) Sorting nexin-1| Length = 522 Score = 97.4 bits (241), Expect = 2e-20 Identities = 48/125 (38%), Positives = 81/125 (64%), Gaps = 10/125 (8%) Frame = +2 Query: 173 LSICVTDPVKMGTGVQSYISYRVITKTNLPEFEGAEKIVIRRYSDFEWLHDRLAEKY--K 346 L++ +TDP K+G G+ +Y++Y+V T+T+LP F + V RR+SDF L+++L+EK+ Sbjct: 145 LTVGITDPEKIGDGMNAYVAYKVTTQTSLPLFRSKQFAVKRRFSDFLGLYEKLSEKHSQN 204 Query: 347 GIFIPPLPEKNAV--------EKFRFSKEFIELRRQALDLFINRLASHPELKQSEDLRTF 502 G +PP PEK+ + ++ S EF+E RR AL+ ++ R+ +HP + Q D+R F Sbjct: 205 GFIVPPPPEKSLIGMTKVKVGKEDSSSAEFLEKRRAALERYLQRIVNHPTMLQDPDVREF 264 Query: 503 LQADE 517 L+ +E Sbjct: 265 LEKEE 269
>SNX12_HUMAN (Q9UMY4) Sorting nexin-12| Length = 172 Score = 89.0 bits (219), Expect = 8e-18 Identities = 56/128 (43%), Positives = 73/128 (57%), Gaps = 7/128 (5%) Frame = +2 Query: 170 FLSICVTDPVKMGTGVQSYISYRVITKTNLPEFEGAEKIVIRRYSDFEWLHDRLAEKYKG 349 FL I + +P +G G + +Y V +TNLP F+ E V RRYSDFEWL + L E+ Sbjct: 29 FLEIDIFNPQTVGVGRARFTTYEVRMRTNLPIFKLKESCVRRRYSDFEWLKNEL-ERDSK 87 Query: 350 IFIPPLPEKNAVEK--FR-----FSKEFIELRRQALDLFINRLASHPELKQSEDLRTFLQ 508 I +PPLP K + FR F + FIE RRQ L+ FIN++A HP + L FLQ Sbjct: 88 IVVPPLPGKALKRQLPFRGDEGIFEESFIEERRQGLEQFINKIAGHPLAQNERCLHMFLQ 147 Query: 509 ADEEKMDR 532 EE +DR Sbjct: 148 --EEAIDR 153
>SNX12_MOUSE (O70493) Sorting nexin-12 (SDP8 protein)| Length = 165 Score = 89.0 bits (219), Expect = 8e-18 Identities = 57/128 (44%), Positives = 76/128 (59%), Gaps = 7/128 (5%) Frame = +2 Query: 170 FLSICVTDPVKMGTGVQSYISYRVITKTNLPEFEGAEKIVIRRYSDFEWLHDRLAEKYKG 349 FL I + +P +G G + +Y V +TNLP F+ E V RRYSDFEWL + L E+ Sbjct: 29 FLEIDIFNPQTVGVGRARFTTYEVRMRTNLPIFKLKESCVRRRYSDFEWLKNEL-ERDSK 87 Query: 350 IFIPPLPEKNAVEK--FR-----FSKEFIELRRQALDLFINRLASHPELKQSEDLRTFLQ 508 I +PPLP K A+++ FR F + FIE RRQ L+ FIN++A HP + L FLQ Sbjct: 88 IVVPPLPGK-ALKRHPFRGDEGIFEESFIEERRQGLEQFINKIAGHPLAQNERCLHMFLQ 146 Query: 509 ADEEKMDR 532 EE +DR Sbjct: 147 --EEAIDR 152
>SNX3_HUMAN (O60493) Sorting nexin-3 (SDP3 protein)| Length = 161 Score = 87.0 bits (214), Expect = 3e-17 Identities = 53/129 (41%), Positives = 74/129 (57%), Gaps = 7/129 (5%) Frame = +2 Query: 170 FLSICVTDPVKMGTGVQSYISYRVITKTNLPEFEGAEKIVIRRYSDFEWLHDRLAEKYKG 349 FL I V++P +G G + +Y + KTNLP F+ E V RRYSDFEWL L E+ Sbjct: 27 FLEIDVSNPQTVGVGRGRFTTYEIRVKTNLPIFKLKESTVRRRYSDFEWLRSEL-ERESK 85 Query: 350 IFIPPLPEKNAVEK--FR-----FSKEFIELRRQALDLFINRLASHPELKQSEDLRTFLQ 508 + +PPLP K + + FR F FIE R+Q L+ FIN++A HP + L FLQ Sbjct: 86 VVVPPLPGKAFLRQLPFRGDDGIFDDNFIEERKQGLEQFINKVAGHPLAQNERCLHMFLQ 145 Query: 509 ADEEKMDRA 535 +E +D++ Sbjct: 146 --DEIIDKS 152
>SNX3_MOUSE (O70492) Sorting nexin-3 (SDP3 protein)| Length = 161 Score = 86.3 bits (212), Expect = 5e-17 Identities = 53/129 (41%), Positives = 73/129 (56%), Gaps = 7/129 (5%) Frame = +2 Query: 170 FLSICVTDPVKMGTGVQSYISYRVITKTNLPEFEGAEKIVIRRYSDFEWLHDRLAEKYKG 349 FL I V++P +G G + +Y + KTNLP F+ E V RRYSDFEWL L E+ Sbjct: 27 FLEIDVSNPQTVGVGRGRFTTYEIRVKTNLPIFKLKESTVRRRYSDFEWLRSEL-ERESK 85 Query: 350 IFIPPLPEKNAVE--KFR-----FSKEFIELRRQALDLFINRLASHPELKQSEDLRTFLQ 508 + +PPLP K + FR F FIE R+Q L+ FIN++A HP + L FLQ Sbjct: 86 VVVPPLPGKAFLRHVPFRGDDGIFDDNFIEERKQGLEQFINKVAGHPLAQNERCLHMFLQ 145 Query: 509 ADEEKMDRA 535 +E +D++ Sbjct: 146 --DEIIDKS 152
>SNX4_CRYNE (Q5KJJ8) Sorting nexin-4 (Autophagy-related protein 24)| Length = 493 Score = 85.9 bits (211), Expect = 7e-17 Identities = 51/169 (30%), Positives = 81/169 (47%), Gaps = 4/169 (2%) Frame = +2 Query: 23 PKSPSPPGSRSFAVPQRGDEPSQGKLAMIXXXXXXXXXXXXXXXXXXXPFLSICVTDPVK 202 P S PP S + G + + ++ + V +P K Sbjct: 40 PSSAQPPASDQYEGYDNSKAGEAGDVGVTLDRRERLGGHEVDGSVWNGKWMDVQVREPAK 99 Query: 203 MGTGVQS-YISYRVITKTNLPEFEGAEKIVIRRYSDFEWLHDRLAEKYKGIFIPPLPEKN 379 G + Y+SY V T+T+LP F +V RR+ DF +L + L + + +PP+P+K+ Sbjct: 100 EHEGSKDMYVSYAVKTETSLPTFRKPLTVVRRRFQDFVFLREHLVKNFPACVVPPIPDKH 159 Query: 380 AVEKF---RFSKEFIELRRQALDLFINRLASHPELKQSEDLRTFLQADE 517 +E RFS EF+E RR L F +R+A HP L++S+ + FLQ+ E Sbjct: 160 RLEYIKGDRFSPEFVERRRLDLQRFADRIARHPVLQRSQLVNDFLQSTE 208
>SNX4_KLULA (Q6CTQ0) Sorting nexin-4 (Autophagy-related protein 24)| Length = 400 Score = 81.6 bits (200), Expect = 1e-15 Identities = 47/118 (39%), Positives = 68/118 (57%), Gaps = 3/118 (2%) Frame = +2 Query: 173 LSICVTDPVKMGTGVQSYISYRVITKTNLPEFEGAEKIVIRRYSDFEWLHDRLAEKYKGI 352 LS+ V+DP K T Q+YI+Y+V TK + + V+RRY+DF LH L + + Sbjct: 17 LSVLVSDPQKQKTHSQTYITYQVSTKI---DGKDEPNCVVRRYNDFVLLHQILINDHPAL 73 Query: 353 FIPPLPEK---NAVEKFRFSKEFIELRRQALDLFINRLASHPELKQSEDLRTFLQADE 517 +PPLP+K N + RFS F + R ++L F+ RL SH EL +S L TFL + + Sbjct: 74 LVPPLPDKKVLNYLSGDRFSHSFTQKRCRSLQTFMRRLLSHSELSKSRILETFLTSTD 131
>SNX18_MOUSE (Q91ZR2) Sorting nexin-18 (Sorting nexin-associated Golgi protein| 1) Length = 614 Score = 78.6 bits (192), Expect = 1e-14 Identities = 48/120 (40%), Positives = 69/120 (57%), Gaps = 3/120 (2%) Frame = +2 Query: 185 VTDPVKMGT--GVQSYISYRVI-TKTNLPEFEGAEKIVIRRYSDFEWLHDRLAEKYKGIF 355 + DP K G++SYISY+++ T T +P V RRY F+WL+ RLAEK+ I Sbjct: 270 IDDPTKQTKFKGMKSYISYKLVPTHTQVP--------VHRRYKHFDWLYARLAEKFPVIS 321 Query: 356 IPPLPEKNAVEKFRFSKEFIELRRQALDLFINRLASHPELKQSEDLRTFLQADEEKMDRA 535 +P LPEK A RF ++FI RR+ L ++N +ASHP L Q + + FL ++A Sbjct: 322 VPHLPEKQATG--RFEEDFISKRRKGLIWWMNHMASHPVLAQCDVFQHFLTCPSSTDEKA 379
>SNX18_HUMAN (Q96RF0) Sorting nexin-18 (Sorting nexin associated Golgi protein| 1) Length = 628 Score = 78.6 bits (192), Expect = 1e-14 Identities = 48/120 (40%), Positives = 69/120 (57%), Gaps = 3/120 (2%) Frame = +2 Query: 185 VTDPVKMGT--GVQSYISYRVI-TKTNLPEFEGAEKIVIRRYSDFEWLHDRLAEKYKGIF 355 + DP K G++SYISY+++ T T +P V RRY F+WL+ RLAEK+ I Sbjct: 280 IDDPTKQTKFKGMKSYISYKLVPTHTQVP--------VHRRYKHFDWLYARLAEKFPVIS 331 Query: 356 IPPLPEKNAVEKFRFSKEFIELRRQALDLFINRLASHPELKQSEDLRTFLQADEEKMDRA 535 +P LPEK A RF ++FI RR+ L ++N +ASHP L Q + + FL ++A Sbjct: 332 VPHLPEKQATG--RFEEDFISKRRKGLIWWMNHMASHPVLAQCDVFQHFLTCPSSTDEKA 389
>SNX4_NEUCR (Q7SGV1) Sorting nexin-4 (Autophagy-related protein 24)| Length = 493 Score = 77.8 bits (190), Expect = 2e-14 Identities = 42/119 (35%), Positives = 67/119 (56%), Gaps = 4/119 (3%) Frame = +2 Query: 173 LSICVTDPVKMGTGVQ-SYISYRVITKTNLPEFEGAEKIVIRRYSDFEWLHDRLAEKYKG 349 L V+DP K G + +Y+SY + T T P F+ + V RR++DF +L+ L Y+ Sbjct: 69 LDCTVSDPHKENDGTKDAYVSYLITTNTTFPSFQKPKTTVRRRFTDFVFLYKVLCRDYQA 128 Query: 350 IFIPPLPEKNAVEKF---RFSKEFIELRRQALDLFINRLASHPELKQSEDLRTFLQADE 517 +PPLP+K +E RF +F R +L F+ RLA HP L++++ L FL++ + Sbjct: 129 CAVPPLPDKQRMEYVRGDRFGTDFTARRAYSLQRFLARLALHPILRKADILHAFLESPD 187
>SNX4_SCHPO (O14243) Sorting nexin-4 (Autophagy-related protein 24)| Length = 401 Score = 76.6 bits (187), Expect = 4e-14 Identities = 49/117 (41%), Positives = 66/117 (56%), Gaps = 4/117 (3%) Frame = +2 Query: 170 FLSICVTDPVKMGTGVQ-SYISYRVITKTNLPEFEGAEKIVIRRYSDFEWLHDRLAEKYK 346 FL VT+P K G + +++SY +ITKTNL F AE V RR+SDF L + L+ + Sbjct: 17 FLQCLVTEPRKELQGSRDTHVSYLIITKTNLSIFTRAECKVRRRFSDFVKLQEILSRMNE 76 Query: 347 GIFIPPLPEKNAVEKF---RFSKEFIELRRQALDLFINRLASHPELKQSEDLRTFLQ 508 +PPLP K+ +E RFS FI R + L+ +I R A HP L QS FL+ Sbjct: 77 DCVVPPLPAKHKLEYIKGGRFSDNFINRRAKLLNRYITRCALHPVLHQSPHFIAFLE 133
>SNX4_CANGA (Q6FPT9) Sorting nexin-4 (Autophagy-related protein 24)| Length = 430 Score = 76.3 bits (186), Expect = 6e-14 Identities = 45/127 (35%), Positives = 68/127 (53%), Gaps = 12/127 (9%) Frame = +2 Query: 173 LSICVTDPVKMG--TGVQSYISYRVITKTNLPEFEGAEK-------IVIRRYSDFEWLHD 325 L I V+DP K G+ Y+SY++ T+T+ P + G +K +V RRY+D LHD Sbjct: 33 LEILVSDPQKRAGEAGLGPYVSYQISTRTDNPSYHGNQKASFDDIIVVHRRYNDVVLLHD 92 Query: 326 RLAEKYKGIFIPPLPEKNAVEKF---RFSKEFIELRRQALDLFINRLASHPELKQSEDLR 496 L + IPPLP+K ++ RF + F + R +L F+ R++ HP L S+ L Sbjct: 93 ILQNDHPTCIIPPLPDKKVLQYIAGDRFGRRFTQRRCHSLQNFLRRVSQHPILSTSKVLE 152 Query: 497 TFLQADE 517 FL +E Sbjct: 153 IFLVGNE 159
>VPS5_YEAST (Q92331) Vacuolar protein sorting-associated protein VPS5| Length = 675 Score = 75.5 bits (184), Expect = 9e-14 Identities = 41/111 (36%), Positives = 66/111 (59%) Frame = +2 Query: 185 VTDPVKMGTGVQSYISYRVITKTNLPEFEGAEKIVIRRYSDFEWLHDRLAEKYKGIFIPP 364 V DPVK+G ++ Y VI++++L E + A+ V RRY DF WL+ +L + G IPP Sbjct: 285 VKDPVKVGELTSIHVEYTVISESSLLELKYAQ--VSRRYRDFRWLYRQLQNNHWGKVIPP 342 Query: 365 LPEKNAVEKFRFSKEFIELRRQALDLFINRLASHPELKQSEDLRTFLQADE 517 PEK +V F+ + FIE RR ++ + ++ P L++ +D FL +D+ Sbjct: 343 PPEKQSVGSFK--ENFIENRRFQMESMLKKICQDPVLQKDKDFLLFLTSDD 391
>SNX4_YEAST (P47057) Sorting nexin-4 (Autophagy-related protein 24) (Cytoplasm| to vacuole targeting protein 13) Length = 423 Score = 74.3 bits (181), Expect = 2e-13 Identities = 49/134 (36%), Positives = 72/134 (53%), Gaps = 13/134 (9%) Frame = +2 Query: 170 FLSICVTDPVKMGTG----VQSYISYRVITKTNLPEFEG----AEKIVI--RRYSDFEWL 319 + I V+DP K TG Y+SY++ TKTN F E I++ RRYSD L Sbjct: 27 WFEIIVSDPQKR-TGDPGSSSGYVSYQISTKTNNTSFYDNRGDPESIIVVHRRYSDLLLL 85 Query: 320 HDRLAEKYKGIFIPPLPEKNAVEKF---RFSKEFIELRRQALDLFINRLASHPELKQSED 490 HD L ++ IPPLP+K + RFS+ F + R +L F+ R++ HP+L QS+ Sbjct: 86 HDILLNRFPTCIIPPLPDKKVFQYIAGDRFSQRFTQKRCHSLQNFLRRVSLHPDLSQSKV 145 Query: 491 LRTFLQADEEKMDR 532 +TFL + + + R Sbjct: 146 FKTFLVSKDWESHR 159
>SNX4_PICPA (Q5H7C3) Sorting nexin-4 (Autophagy-related protein 24) (Pexophagy| zeocin-resistent mutant protein 16) Length = 661 Score = 73.9 bits (180), Expect = 3e-13 Identities = 43/111 (38%), Positives = 62/111 (55%), Gaps = 3/111 (2%) Frame = +2 Query: 185 VTDPVKMGTGVQSYISYRVITKTNLPEFEGAEKIVIRRYSDFEWLHDRLAEKYKGIFIPP 364 V+ P+K G YISY + T+TN P + V RR+SD +L++ LA + IPP Sbjct: 83 VSQPLKESDGQNFYISYLIETETNEPGLAKTKLKVRRRFSDSNFLYNCLANDFPTSIIPP 142 Query: 365 LPEKNAVEKF---RFSKEFIELRRQALDLFINRLASHPELKQSEDLRTFLQ 508 LP K +E RF + F R AL+ F+NR++ HP LKQ++ FL+ Sbjct: 143 LPNKQRLEYIKGDRFGEYFTTKRSIALNNFLNRISKHPLLKQAKIYHIFLE 193
>SNX4_ASHGO (Q75C43) Sorting nexin-4 (Autophagy-related protein 24)| Length = 410 Score = 73.6 bits (179), Expect = 4e-13 Identities = 47/124 (37%), Positives = 68/124 (54%), Gaps = 11/124 (8%) Frame = +2 Query: 179 ICVTDPVKMG---TGVQSYISYRVITKTNLPEFEGAEK-------IVIRRYSDFEWLHDR 328 I V+DP K + SY++Y++ +K P EG ++ +V RRYSDF L+ Sbjct: 12 IIVSDPQKQRGDKSSSGSYVTYQISSK---PATEGDKRSGEDDITVVHRRYSDFVLLYQI 68 Query: 329 LAEKYKGIFIPPLPEKNAVEKF-RFSKEFIELRRQALDLFINRLASHPELKQSEDLRTFL 505 LA Y +PPLP+K + RFS+ F + R +L F+ RLA HP L QS+ L TFL Sbjct: 69 LANDYPACIVPPLPDKKVLNYLDRFSQSFTQKRCHSLQNFLQRLAQHPVLSQSKILHTFL 128 Query: 506 QADE 517 + + Sbjct: 129 VSSD 132
>SNX4_EMENI (Q5B797) Sorting nexin-4 (Autophagy-related protein 24)| Length = 487 Score = 73.2 bits (178), Expect = 5e-13 Identities = 42/115 (36%), Positives = 65/115 (56%), Gaps = 4/115 (3%) Frame = +2 Query: 185 VTDPVKMGTGVQ-SYISYRVITKTNLPEFEGAEKIVIRRYSDFEWLHDRLAEKYKGIFIP 361 V P+K G + +YISY V T T+ F+ A+ V RR++DF +L+ L +Y +P Sbjct: 75 VDTPIKENDGTKDAYISYLVTTHTDFKSFQKADFTVRRRFTDFVFLYKTLYREYPACAVP 134 Query: 362 PLPEKNAVEKF---RFSKEFIELRRQALDLFINRLASHPELKQSEDLRTFLQADE 517 PLP+K+ +E RF EF R +L F+ RL HP L+++ L FL++ + Sbjct: 135 PLPDKHKMEYVRGDRFGAEFTTRRAWSLHRFLKRLTLHPVLRRAPLLAIFLESPD 189
>SNX4_MAGGR (Q522W5) Sorting nexin-4 (Autophagy-related protein 24)| Length = 495 Score = 72.4 bits (176), Expect = 8e-13 Identities = 40/115 (34%), Positives = 65/115 (56%), Gaps = 4/115 (3%) Frame = +2 Query: 185 VTDPVKMGTGVQ-SYISYRVITKTNLPEFEGAEKIVIRRYSDFEWLHDRLAEKYKGIFIP 361 V+ P+K G + +++SY V T T +F+ + V RR++DF +L L+ +Y +P Sbjct: 67 VSSPLKENDGTKDAFVSYLVTTHTTFADFQKPDASVRRRFTDFVFLFKTLSREYPASAVP 126 Query: 362 PLPEKNAVEKF---RFSKEFIELRRQALDLFINRLASHPELKQSEDLRTFLQADE 517 PLP+K +E RF +F R +L F+ R A HP L++S L TFL++ + Sbjct: 127 PLPDKQRMEYVRGDRFGNDFTSRRAYSLRRFLARCALHPVLRRSAILHTFLESPD 181
>SNX4_ASPFU (Q4WQI6) Sorting nexin-4 (Autophagy-related protein 24)| Length = 497 Score = 72.4 bits (176), Expect = 8e-13 Identities = 42/115 (36%), Positives = 64/115 (55%), Gaps = 4/115 (3%) Frame = +2 Query: 185 VTDPVKMGTGVQ-SYISYRVITKTNLPEFEGAEKIVIRRYSDFEWLHDRLAEKYKGIFIP 361 V P+K G + +YISY V T T+ F+ + V RR++DF +L+ L +Y +P Sbjct: 77 VDSPLKENDGTKDAYISYLVTTHTDFKSFQKPDFAVRRRFTDFYFLYKTLYREYPACAVP 136 Query: 362 PLPEKNAVEKF---RFSKEFIELRRQALDLFINRLASHPELKQSEDLRTFLQADE 517 PLPEK+ +E RF EF R +L F+ RL HP L+++ L FL++ + Sbjct: 137 PLPEKHKMEYVTGDRFGPEFTSRRAWSLHRFLKRLTLHPVLRRAPLLAIFLESPD 191
>VPS5_SCHPO (Q9C0U7) Vacuolar protein sorting-associated protein vps5| Length = 576 Score = 70.9 bits (172), Expect = 2e-12 Identities = 39/113 (34%), Positives = 62/113 (54%), Gaps = 1/113 (0%) Frame = +2 Query: 179 ICVTDPVKMGTGVQSYISYRVITKTNLPEFEGAEKIVI-RRYSDFEWLHDRLAEKYKGIF 355 I V DP + +S+ Y V T+ + + RRY+DF +L+ L+ + G Sbjct: 204 IQVHDPHTVKEITKSHTVYSVSTRLEEHNQPSVSNVTVQRRYNDFAFLYQLLSNNHPGCI 263 Query: 356 IPPLPEKNAVEKFRFSKEFIELRRQALDLFINRLASHPELKQSEDLRTFLQAD 514 IPP+PEK V RF EFIE RR AL++ + ++++HP L+ + FL+A+ Sbjct: 264 IPPIPEKQVVG--RFDDEFIEQRRAALEVMLRKISAHPVLRDDYSFKLFLEAE 314
>SNX9_HUMAN (Q9Y5X1) Sorting nexin-9 (SH3 and PX domain-containing protein 1)| (SDP1 protein) Length = 595 Score = 67.0 bits (162), Expect = 3e-11 Identities = 43/116 (37%), Positives = 64/116 (55%), Gaps = 3/116 (2%) Frame = +2 Query: 185 VTDPVKMGT--GVQSYISYRVITKTNLPEFEGAEKIVIRRYSDFEWLHDRLAEKY-KGIF 355 V DP K G++SYI Y+ +T TN + V RY F+WL++RL K+ I Sbjct: 254 VADPRKGSKMYGLKSYIEYQ-LTPTN------TNRSVNHRYKHFDWLYERLLVKFGSAIP 306 Query: 356 IPPLPEKNAVEKFRFSKEFIELRRQALDLFINRLASHPELKQSEDLRTFLQADEEK 523 IP LP+K RF +EFI++R + L ++ R+ HP + +SE + FL +EK Sbjct: 307 IPSLPDKQVTG--RFEEEFIKMRMERLQAWMTRMCRHPVISESEVFQQFLNFRDEK 360
>SNX9_MOUSE (Q91VH2) Sorting nexin-9| Length = 595 Score = 66.6 bits (161), Expect = 4e-11 Identities = 43/116 (37%), Positives = 64/116 (55%), Gaps = 3/116 (2%) Frame = +2 Query: 185 VTDPVKMGT--GVQSYISYRVITKTNLPEFEGAEKIVIRRYSDFEWLHDRLAEKY-KGIF 355 V DP K G++SYI Y+ +T TN + V RY F+WL++RL K+ I Sbjct: 254 VADPRKGSKMYGLKSYIEYQ-LTPTN------TNRSVNHRYKHFDWLYERLLVKFGSAIP 306 Query: 356 IPPLPEKNAVEKFRFSKEFIELRRQALDLFINRLASHPELKQSEDLRTFLQADEEK 523 IP LP+K RF +EFI++R + L ++ R+ HP + +SE + FL +EK Sbjct: 307 IPSLPDKQVTG--RFEEEFIKMRMERLQAWMTRMCRHPVVSESEVFQQFLNFRDEK 360
>SNX5_HUMAN (Q9Y5X3) Sorting nexin-5| Length = 404 Score = 65.5 bits (158), Expect = 1e-10 Identities = 42/134 (31%), Positives = 63/134 (47%), Gaps = 29/134 (21%) Frame = +2 Query: 227 ISYRVITKTNLPEFEGAEKIVIRRYSDFEWLHDRLAE--KYKGIFIPPLPEK-------- 376 + + V TKT LP F+ E V R++ DF WLHD L E Y G+ IPP P K Sbjct: 45 VKFTVHTKTTLPTFQSPEFSVTRQHEDFVWLHDTLIETTDYAGLIIPPAPTKPDFDGPRE 104 Query: 377 ---------NAVEKFRFSKEFIELRRQAL----------DLFINRLASHPELKQSEDLRT 499 ++ K F+K EL + L ++F+ RL+SHP L + + Sbjct: 105 KMQKLGEGEGSMTKEEFAKMKQELEAEYLAVFKKTVSSHEVFLQRLSSHPVLSKDRNFHV 164 Query: 500 FLQADEEKMDRARS 541 FL+ D++ R ++ Sbjct: 165 FLEYDQDLSVRRKN 178
>SNX5_MOUSE (Q9D8U8) Sorting nexin-5| Length = 404 Score = 62.8 bits (151), Expect = 6e-10 Identities = 41/134 (30%), Positives = 62/134 (46%), Gaps = 29/134 (21%) Frame = +2 Query: 227 ISYRVITKTNLPEFEGAEKIVIRRYSDFEWLHDRLAE--KYKGIFIPPLPEK-------- 376 + + V TKT L F+ E V R++ DF WLHD L E Y G+ IPP P K Sbjct: 45 VKFTVHTKTTLSTFQSPEFSVTRQHEDFVWLHDTLTETTDYAGLIIPPAPTKPDFDGPRE 104 Query: 377 ---------NAVEKFRFSKEFIELRRQAL----------DLFINRLASHPELKQSEDLRT 499 ++ K F+K EL + L ++F+ RL+SHP L + + Sbjct: 105 KMQKLGEGEGSMTKEEFAKMKQELEAEYLAVFKKTVSTHEVFLQRLSSHPVLSKDRNFHV 164 Query: 500 FLQADEEKMDRARS 541 FL+ D++ R ++ Sbjct: 165 FLEYDQDLSVRRKN 178
>SNX3_YEAST (Q08826) Sorting nexin GRD19| Length = 162 Score = 61.6 bits (148), Expect = 1e-09 Identities = 45/126 (35%), Positives = 68/126 (53%), Gaps = 10/126 (7%) Frame = +2 Query: 170 FLSICVTDP-VKMGTGVQS---YISYRVITKTNLPEFEGAEKIVIRRYSDFEWLHDRLAE 337 FL I V +P + G+ S + Y +I +TNLP F V RRYSDFE+ L + Sbjct: 35 FLEIEVHNPKTHIPNGMDSKGMFTDYEIICRTNLPSFHKRVSKVRRRYSDFEFFRKCLIK 94 Query: 338 K-----YKGIFIPPLPEKNAVEKFRFSKEFIELRRQALDLFINRLASHPELKQ-SEDLRT 499 + + + +P LP K + RFS E IE RRQ L+ ++ +A HP L+ S+ L Sbjct: 95 EISMLNHPKVMVPHLPGKILLSN-RFSNEVIEERRQGLNTWMQSVAGHPLLQSGSKVLVR 153 Query: 500 FLQADE 517 F++A++ Sbjct: 154 FIEAEK 159
>SNX11_HUMAN (Q9Y5W9) Sorting nexin-11| Length = 270 Score = 60.5 bits (145), Expect = 3e-09 Identities = 38/114 (33%), Positives = 53/114 (46%), Gaps = 1/114 (0%) Frame = +2 Query: 173 LSICVTDPVKMGTGV-QSYISYRVITKTNLPEFEGAEKIVIRRYSDFEWLHDRLAEKYKG 349 +++ V DP G SY+ Y++ TN F V RRY +F WL +L Sbjct: 17 ITVRVQDPRVQNEGSWNSYVDYKIFLHTNSKAFTAKTSCVRRRYREFVWLRKQLQRNAGL 76 Query: 350 IFIPPLPEKNAVEKFRFSKEFIELRRQALDLFINRLASHPELKQSEDLRTFLQA 511 + +P LP K+ F S EFIE RRQ L F+ ++ L L FLQ+ Sbjct: 77 VPVPELPGKSTF--FGTSDEFIEKRRQGLQHFLEKVLQSVVLLSDSQLHLFLQS 128
>SNX11_MOUSE (Q91WL6) Sorting nexin-11| Length = 271 Score = 60.1 bits (144), Expect = 4e-09 Identities = 38/114 (33%), Positives = 53/114 (46%), Gaps = 1/114 (0%) Frame = +2 Query: 173 LSICVTDPVKMGTGV-QSYISYRVITKTNLPEFEGAEKIVIRRYSDFEWLHDRLAEKYKG 349 +++ V DP G SY+ Y++ TN F V RRY +F WL +L Sbjct: 17 ITVRVQDPRVQNEGSWNSYVDYKIFLHTNSKAFTAKTSCVRRRYREFVWLRKQLQRNAGL 76 Query: 350 IFIPPLPEKNAVEKFRFSKEFIELRRQALDLFINRLASHPELKQSEDLRTFLQA 511 + +P LP K+ F S EFIE RRQ L F+ ++ L L FLQ+ Sbjct: 77 VPVPELPGKSTF--FGGSDEFIEKRRQGLQHFLEKVLQSVVLLSDSQLHLFLQS 128
>SNX4_CANAL (Q5AD77) Sorting nexin-4 (Autophagy-related protein 24)| Length = 630 Score = 58.9 bits (141), Expect = 9e-09 Identities = 41/124 (33%), Positives = 60/124 (48%), Gaps = 17/124 (13%) Frame = +2 Query: 185 VTDPVK-MGTGVQSYISYRVITKTNLPEF----------EGAEKI---VIRRYSDFEWLH 322 VT P + + T + +ISY V T T+ P +G E + V RRY DF +L+ Sbjct: 192 VTHPNRDLDTASKPFISYLVTTTTDNPSILKLTKEKKPKQGEEYLTFSVRRRYGDFRYLY 251 Query: 323 DRLAEKYKGIFIPPLPEKNAVEKF---RFSKEFIELRRQALDLFINRLASHPELKQSEDL 493 + L+ + + IPPLP K+ + FS EF+ R +LD FI + H L QS Sbjct: 252 ESLSNDFPTVMIPPLPSKSNFKYLTGDTFSSEFVHKRLHSLDRFIRFILQHKILSQSSIF 311 Query: 494 RTFL 505 F+ Sbjct: 312 HLFI 315
>SNX4_DEBHA (Q6BZE9) Sorting nexin-4 (Autophagy-related protein 24)| Length = 582 Score = 57.4 bits (137), Expect = 3e-08 Identities = 39/127 (30%), Positives = 61/127 (48%), Gaps = 16/127 (12%) Frame = +2 Query: 173 LSICVTDPVK-MGTGVQSYISYRVITKTNLPEF---------EGAEKIVI---RRYSDFE 313 +++ VT P++ + + + YISY + T TN P +G E + I RRY DF Sbjct: 117 INVVVTSPLRDLDSSSKPYISYLLTTATNHPSVMKLSTVKKEQGKEVVEITARRRYGDFR 176 Query: 314 WLHDRLAEKYKGIFIPPLPEK---NAVEKFRFSKEFIELRRQALDLFINRLASHPELKQS 484 +L D L+ + + +PPLP K + FS EF+ R +LD F+ + H L Q Sbjct: 177 FLFDCLSNDHPEVMMPPLPSKLNFKYLTGDTFSTEFVHKRLHSLDRFVRFITCHKVLSQL 236 Query: 485 EDLRTFL 505 F+ Sbjct: 237 SIFHLFV 243
>SNX10_MOUSE (Q9CWT3) Sorting nexin-10| Length = 201 Score = 57.4 bits (137), Expect = 3e-08 Identities = 36/115 (31%), Positives = 55/115 (47%), Gaps = 1/115 (0%) Frame = +2 Query: 170 FLSICVTDP-VKMGTGVQSYISYRVITKTNLPEFEGAEKIVIRRYSDFEWLHDRLAEKYK 346 F+S+ V DP ++ SYI Y + TN F V RRY +F WL RL Sbjct: 10 FVSVWVRDPRIQKEDFWHSYIDYEICIHTNSMCFTMKTSCVRRRYREFVWLRQRLQSNAL 69 Query: 347 GIFIPPLPEKNAVEKFRFSKEFIELRRQALDLFINRLASHPELKQSEDLRTFLQA 511 + +P LP KN +++ ++ RRQ L+ F+ ++ + L L FLQ+ Sbjct: 70 LVQLPELPSKNLFFNMN-NRQHVDQRRQGLEDFLRKVLQNALLLSDSSLHLFLQS 123
>SNX10_HUMAN (Q9Y5X0) Sorting nexin-10| Length = 201 Score = 57.4 bits (137), Expect = 3e-08 Identities = 36/115 (31%), Positives = 55/115 (47%), Gaps = 1/115 (0%) Frame = +2 Query: 170 FLSICVTDP-VKMGTGVQSYISYRVITKTNLPEFEGAEKIVIRRYSDFEWLHDRLAEKYK 346 F+S+ V DP ++ SYI Y + TN F V RRY +F WL RL Sbjct: 10 FVSVWVRDPRIQKEDFWHSYIDYEICIHTNSMCFTMKTSCVRRRYREFVWLRQRLQSNAL 69 Query: 347 GIFIPPLPEKNAVEKFRFSKEFIELRRQALDLFINRLASHPELKQSEDLRTFLQA 511 + +P LP KN +++ ++ RRQ L+ F+ ++ + L L FLQ+ Sbjct: 70 LVQLPELPSKNLFFNMN-NRQHVDQRRQGLEDFLRKVLQNALLLSDSSLHLFLQS 123
>MVP1_YEAST (P40959) Sorting nexin MVP1| Length = 511 Score = 56.2 bits (134), Expect = 6e-08 Identities = 33/93 (35%), Positives = 50/93 (53%), Gaps = 2/93 (2%) Frame = +2 Query: 278 EKIVIRRYSDFEWLHDRLAEKYKGIFIPPLPEKNAVEKFRFSKEFIELRRQALDLFINRL 457 E+ V+RRYSDF WL + L ++Y IP LP K + + F++ RR L FIN + Sbjct: 166 ERTVVRRYSDFLWLREILLKRYPFRMIPELPPKR-IGSQNADQLFLKKRRIGLSRFINLV 224 Query: 458 ASHPELKQSEDLRTFL--QADEEKMDRARSYET 550 HP+L + + TFL + D + +Y+T Sbjct: 225 MKHPKLSNDDLVLTFLTVRTDLTSWRKQATYDT 257
>SNX6_PONPY (Q5R613) Sorting nexin-6| Length = 406 Score = 55.1 bits (131), Expect = 1e-07 Identities = 36/134 (26%), Positives = 64/134 (47%), Gaps = 29/134 (21%) Frame = +2 Query: 227 ISYRVITKTNLPEFEGAEKIVIRRYSDFEWLHDRLAEK--YKGIFIPPLPEK-------- 376 + + V TK++LP F+ E V+R++ +F WLHD E Y G IPP P + Sbjct: 46 VKFTVHTKSSLPNFKQNEFSVVRQHEEFIWLHDSFVENEDYAGYIIPPAPPRPDFDASRE 105 Query: 377 ---------NAVEKFRFSKEFIELRRQAL----------DLFINRLASHPELKQSEDLRT 499 ++ K F+K EL + L ++F+ R+A+HP L++ + Sbjct: 106 KLQKLGEGEGSMTKEEFTKMKQELEAEYLAIFKKTVAMHEVFLCRVAAHPILRKDLNFHV 165 Query: 500 FLQADEEKMDRARS 541 FL+ +++ R ++ Sbjct: 166 FLEYNQDLSVRGKN 179
>SNX6_HUMAN (Q9UNH7) Sorting nexin-6 (TRAF4-associated factor 2)| Length = 406 Score = 55.1 bits (131), Expect = 1e-07 Identities = 36/134 (26%), Positives = 64/134 (47%), Gaps = 29/134 (21%) Frame = +2 Query: 227 ISYRVITKTNLPEFEGAEKIVIRRYSDFEWLHDRLAEK--YKGIFIPPLPEK-------- 376 + + V TK++LP F+ E V+R++ +F WLHD E Y G IPP P + Sbjct: 46 VKFTVHTKSSLPNFKQNEFSVVRQHEEFIWLHDSFVENEDYAGYIIPPAPPRPDFDASRE 105 Query: 377 ---------NAVEKFRFSKEFIELRRQAL----------DLFINRLASHPELKQSEDLRT 499 ++ K F+K EL + L ++F+ R+A+HP L++ + Sbjct: 106 KLQKLGEGEGSMTKEEFTKMKQELEAEYLAIFKKTVAMHEVFLCRVAAHPILRRDLNFHV 165 Query: 500 FLQADEEKMDRARS 541 FL+ +++ R ++ Sbjct: 166 FLEYNQDLSVRGKN 179
>SNX4_PONPY (Q5R4C2) Sorting nexin-4| Length = 450 Score = 52.8 bits (125), Expect = 7e-07 Identities = 35/105 (33%), Positives = 55/105 (52%), Gaps = 9/105 (8%) Frame = +2 Query: 218 QSYISYRVITKTNLPEFEGAEKI---VIRRYSDFEWLHDRLAEKYKGIFIPPLPEKNA-- 382 ++Y +Y + T++ + +G + + RRYS+FE L L Y I +PPLPEK A Sbjct: 78 ETYTAYLIETRS-IEHTDGQSVLTDSLWRRYSEFELLRSYLLVYYPHIVVPPLPEKRAEF 136 Query: 383 ----VEKFRFSKEFIELRRQALDLFINRLASHPELKQSEDLRTFL 505 + +F+E RR L+ F+ R+ASHP L + + FL Sbjct: 137 VWHKLSADNMDPDFVERRRIGLENFLLRIASHPLLCRDKIFYLFL 181
>SNX4_HUMAN (O95219) Sorting nexin-4| Length = 450 Score = 52.4 bits (124), Expect = 9e-07 Identities = 31/77 (40%), Positives = 41/77 (53%), Gaps = 6/77 (7%) Frame = +2 Query: 293 RRYSDFEWLHDRLAEKYKGIFIPPLPEKNA------VEKFRFSKEFIELRRQALDLFINR 454 RRYS+FE L L Y I +PPLPEK A + +F+E RR L+ F+ R Sbjct: 105 RRYSEFELLRSYLLVYYPHIVVPPLPEKRAEFVWHKLSADNMDPDFVERRRIGLENFLLR 164 Query: 455 LASHPELKQSEDLRTFL 505 +ASHP L + + FL Sbjct: 165 IASHPILCRDKIFYLFL 181
>SGK3_HUMAN (Q96BR1) Serine/threonine-protein kinase Sgk3 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 3) (Serum/glucocorticoid-regulated kinase-like) Length = 496 Score = 50.4 bits (119), Expect = 3e-06 Identities = 29/83 (34%), Positives = 46/83 (55%) Frame = +2 Query: 275 AEKIVIRRYSDFEWLHDRLAEKYKGIFIPPLPEKNAVEKFRFSKEFIELRRQALDLFINR 454 +E V RRY++F+ L++ L +++ + + +P K F +FI+ RR L+ FI Sbjct: 43 SEWFVFRRYAEFDKLYNTLKKQFPAMALK-IPAKRIFGD-NFDPDFIKQRRAGLNEFIQN 100 Query: 455 LASHPELKQSEDLRTFLQADEEK 523 L +PEL D+R FLQ D K Sbjct: 101 LVRYPELYNHPDVRAFLQMDSPK 123
>SNX41_YARLI (Q6C9X0) Sorting nexin-41| Length = 570 Score = 50.4 bits (119), Expect = 3e-06 Identities = 27/80 (33%), Positives = 44/80 (55%), Gaps = 7/80 (8%) Frame = +2 Query: 287 VIRRYSDFEWLHDRLAEKYKGIFIPPLPEKNAV-------EKFRFSKEFIELRRQALDLF 445 V RRYS+FE L L + + +PP+PEK+++ K R K+ IE R++ L +F Sbjct: 150 VRRRYSEFESLRTTLTRMFPTLIVPPIPEKHSITDYAVAPTKAREDKDMIEHRQRMLQVF 209 Query: 446 INRLASHPELKQSEDLRTFL 505 +NR + P++ + FL Sbjct: 210 LNRCRNLPQISNCIVFQRFL 229
>SNX8_HUMAN (Q9Y5X2) Sorting nexin-8| Length = 465 Score = 50.1 bits (118), Expect = 4e-06 Identities = 29/73 (39%), Positives = 39/73 (53%) Frame = +2 Query: 287 VIRRYSDFEWLHDRLAEKYKGIFIPPLPEKNAVEKFRFSKEFIELRRQALDLFINRLASH 466 V RRY+DF + L K+ +P LP K + R EFIE RR+AL F+N +A H Sbjct: 106 VYRRYNDFVVFQEMLLHKFPYRMVPALPPKRMLGADR---EFIEARRRALKRFVNLVARH 162 Query: 467 PELKQSEDLRTFL 505 P + L+ FL Sbjct: 163 PLFSEDVVLKLFL 175
>SGK3_MOUSE (Q9ERE3) Serine/threonine-protein kinase Sgk3 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 3) (Serum/glucocorticoid-regulated kinase-like) (Cytokine independent survival kinase) Length = 496 Score = 49.3 bits (116), Expect = 7e-06 Identities = 28/83 (33%), Positives = 46/83 (55%) Frame = +2 Query: 275 AEKIVIRRYSDFEWLHDRLAEKYKGIFIPPLPEKNAVEKFRFSKEFIELRRQALDLFINR 454 +E V RRY++F+ L++ L +++ + + +P K F +FI+ RR L+ FI Sbjct: 43 SEWFVFRRYAEFDKLYNSLKKQFPAMALK-IPAKRIFGD-NFDPDFIKQRRAGLNEFIQN 100 Query: 455 LASHPELKQSEDLRTFLQADEEK 523 L +PEL D+R FLQ D + Sbjct: 101 LVRYPELYNHPDVRAFLQMDSPR 123
>SNX41_SCHPO (O60107) Sorting nexin-41| Length = 586 Score = 49.3 bits (116), Expect = 7e-06 Identities = 27/77 (35%), Positives = 41/77 (53%), Gaps = 7/77 (9%) Frame = +2 Query: 296 RYSDFEWLHDRLAEKYKGIFIPPLPEKNAVEKFRFS-------KEFIELRRQALDLFINR 454 RYS+F L +L+ Y +PPLP+K+ + + + +E R++ L LF+ R Sbjct: 103 RYSEFASLRVQLSRLYPTCLVPPLPDKHKIMDYLINVTKNQRMSRMLEERKRLLQLFLRR 162 Query: 455 LASHPELKQSEDLRTFL 505 +A HP L SE R FL Sbjct: 163 VAQHPILGLSEVFRKFL 179
>SNX41_CRYNE (Q5KKB9) Sorting nexin-41| Length = 638 Score = 48.9 bits (115), Expect = 9e-06 Identities = 36/109 (33%), Positives = 48/109 (44%), Gaps = 8/109 (7%) Frame = +2 Query: 212 GVQSYISYRVITKTNLPEFEGAEKIVIRRYSDFEWLHDRLAEKYKGIFIPPLPEKNAV-- 385 G SYI+Y + T+ V RRYS F LH L Y + IPP+P K ++ Sbjct: 99 GTASYITYVIRLGTHT---------VRRRYSAFLSLHQSLTGLYPVLIIPPIPSKQSLTD 149 Query: 386 ------EKFRFSKEFIELRRQALDLFINRLASHPELKQSEDLRTFLQAD 514 K R I R++ L+ F+ RL HP L L FL+ D Sbjct: 150 YAVKGQSKAREDATIIARRKRLLEDFLQRLIRHPILGGEHVLHRFLEED 198
>SNX41_EMENI (Q5AZC9) Sorting nexin-41| Length = 615 Score = 47.4 bits (111), Expect = 3e-05 Identities = 32/112 (28%), Positives = 54/112 (48%), Gaps = 7/112 (6%) Frame = +2 Query: 167 PFLSICVTDPVKMGTGVQSYISYRVITKTNLPEFEGAEKIVIRRYSDFEWLHDRLAEKYK 346 P + I +TD K G S+I Y + T + V RRYS+F L L + Sbjct: 93 PDMPILITDAGKNHEGGGSFIVYTIRT---------GDLEVRRRYSEFASLRQTLVSLHP 143 Query: 347 GIFIPPLPEKNAV-------EKFRFSKEFIELRRQALDLFINRLASHPELKQ 481 + +PP+PEK+++ K + I+LR++ L +F+NR E+++ Sbjct: 144 TLIVPPIPEKHSMADYAAKPTKAKEDAGIIDLRKRMLAVFLNRCRRMKEIRE 195
>KS6C1_MOUSE (Q8BLK9) Ribosomal protein S6 kinase delta-1 (EC 2.7.11.1) (52 kDa| ribosomal protein S6 kinase) Length = 1056 Score = 46.6 bits (109), Expect = 5e-05 Identities = 37/114 (32%), Positives = 56/114 (49%), Gaps = 6/114 (5%) Frame = +2 Query: 185 VTDPVKMGTGVQSY-ISYRVITKTNLPEFEGAEKIVIRRYSDFEWLHDRLAEKYKGIF-- 355 VT+P + G Y ++ RV+++ N + + E IV RRYSDF+ LH L + ++ F Sbjct: 17 VTEPQRHPRGYTVYKVTARVVSRRNPEDVQ--EIIVWRRYSDFKKLHRELWQIHRNAFRH 74 Query: 356 ---IPPLPEKNAVEKFRFSKEFIELRRQALDLFINRLASHPELKQSEDLRTFLQ 508 PP + RF K IE RRQ + + A+ P L S L+ F + Sbjct: 75 SELFPPFAKGTVFG--RFDKTVIEERRQCAEDLLQFSANIPALYNSRQLQDFFK 126
>KS6C1_HUMAN (Q96S38) Ribosomal protein S6 kinase delta-1 (EC 2.7.11.1) (52 kDa| ribosomal protein S6 kinase) (Ribosomal S6 kinase-like protein with two PSK domains 118 kDa protein) (SPHK1-binding protein) Length = 1066 Score = 46.6 bits (109), Expect = 5e-05 Identities = 36/114 (31%), Positives = 58/114 (50%), Gaps = 6/114 (5%) Frame = +2 Query: 185 VTDPVKMGTGVQSY-ISYRVITKTNLPEFEGAEKIVIRRYSDFEWLHDRLAEKYKGIF-- 355 VT+P + G Y ++ RV+++ N + + E IV +RYSDF+ LH L + +K +F Sbjct: 17 VTEPQRHPRGYTVYKVTARVVSRRNPEDVQ--EIIVWKRYSDFKKLHKELWQIHKNLFRH 74 Query: 356 ---IPPLPEKNAVEKFRFSKEFIELRRQALDLFINRLASHPELKQSEDLRTFLQ 508 PP + + RF + IE RRQ + + A+ P L S+ L F + Sbjct: 75 SELFPPFAK--GIVFGRFDETVIEERRQCAEDLLQFSANIPALYNSKQLEDFFK 126
>SNX16_RAT (P57769) Sorting nexin-16| Length = 344 Score = 46.6 bits (109), Expect = 5e-05 Identities = 30/95 (31%), Positives = 50/95 (52%) Frame = +2 Query: 233 YRVITKTNLPEFEGAEKIVIRRYSDFEWLHDRLAEKYKGIFIPPLPEKNAVEKFRFSKEF 412 Y+++ K + E +V RRY+DF L+D+L E + G F LP K K ++ +F Sbjct: 127 YKILVKKSPEE----SWVVFRRYTDFSRLNDKLKEMFPG-FRLALPPKRWF-KDNYNADF 180 Query: 413 IELRRQALDLFINRLASHPELKQSEDLRTFLQADE 517 +E R+ L F+ L +H ++ +R FL D+ Sbjct: 181 LEDRQLGLQAFLQNLVAHKDIANCLAVREFLCLDD 215
>SNX16_HUMAN (P57768) Sorting nexin-16| Length = 343 Score = 46.2 bits (108), Expect = 6e-05 Identities = 30/95 (31%), Positives = 49/95 (51%) Frame = +2 Query: 233 YRVITKTNLPEFEGAEKIVIRRYSDFEWLHDRLAEKYKGIFIPPLPEKNAVEKFRFSKEF 412 Y+++ K E +V RRY+DF L+D+L E + G F LP K K ++ +F Sbjct: 127 YKILVKKTPEE----SWVVFRRYTDFSRLNDKLKEMFPG-FRLALPPKRWF-KDNYNADF 180 Query: 413 IELRRQALDLFINRLASHPELKQSEDLRTFLQADE 517 +E R+ L F+ L +H ++ +R FL D+ Sbjct: 181 LEDRQLGLQAFLQNLVAHKDIANCLAVREFLCLDD 215
>SNX41_NEUCR (Q7SB54) Sorting nexin-41| Length = 604 Score = 45.4 bits (106), Expect = 1e-04 Identities = 30/103 (29%), Positives = 50/103 (48%), Gaps = 7/103 (6%) Frame = +2 Query: 167 PFLSICVTDPVKMGTGVQSYISYRVITKTNLPEFEGAEKIVIRRYSDFEWLHDRLAEKYK 346 P L I +T+ K +I Y + T + V RRYS+F L D L + Sbjct: 108 PELPILITEAGKSQESGGRFIVYTIKT---------GDLTVRRRYSEFASLRDALTRLHP 158 Query: 347 GIFIPPLPEKNAVEKF-------RFSKEFIELRRQALDLFINR 454 + IPP+PEK+ + + + ++ I+LR++ L +F+NR Sbjct: 159 TLVIPPIPEKHTMADYAANPTNAKQDQQIIDLRKRMLAVFLNR 201
>SNX21_HUMAN (Q969T3) Sorting nexin-21 (Sorting nexin L) (SNX-L)| Length = 373 Score = 44.7 bits (104), Expect = 2e-04 Identities = 30/86 (34%), Positives = 46/86 (53%), Gaps = 1/86 (1%) Frame = +2 Query: 287 VIRRYSDFEWLHDRLAEKYKG-IFIPPLPEKNAVEKFRFSKEFIELRRQALDLFINRLAS 463 + RRYSDFE LH L +++G + P K + F+ E I R +A + F+ L + Sbjct: 168 ISRRYSDFERLHRNLQRQFRGPMAAISFPRKRL--RRNFTAETIARRSRAFEQFLGHLQA 225 Query: 464 HPELKQSEDLRTFLQADEEKMDRARS 541 PEL+ + DL+ F E + RA+S Sbjct: 226 VPELRHAPDLQDFFVLPE--LRRAQS 249
>SNX41_KLULA (Q6CWX3) Sorting nexin-41| Length = 575 Score = 43.5 bits (101), Expect = 4e-04 Identities = 28/91 (30%), Positives = 44/91 (48%), Gaps = 7/91 (7%) Frame = +2 Query: 263 EFEGAEKIVIRRYSDFEWLHDRLAEKYKGIFIPPLPEKNAVEKFRFSK-------EFIEL 421 EF G +V RRYS+F+ L L I IPP+P K+ + K+ F+ + IE Sbjct: 130 EFGGI--VVTRRYSEFDSLRQSLCRLLPTIIIPPIPSKHPIIKYLFNPLHAKKDIKIIER 187 Query: 422 RRQALDLFINRLASHPELKQSEDLRTFLQAD 514 R++ L F+N E++ + FL + Sbjct: 188 RQRLLSRFLNNCHKVREIRNHIVFQKFLNPE 218
>SNX41_CANAL (Q5AD73) Sorting nexin-41| Length = 681 Score = 42.4 bits (98), Expect = 9e-04 Identities = 21/72 (29%), Positives = 40/72 (55%), Gaps = 7/72 (9%) Frame = +2 Query: 284 IVIRRYSDFEWLHDRLAEKYKGIFIPPLPEKNAVEKFRFSK-------EFIELRRQALDL 442 +V RRYS+F+ L D L + + + IPP+PEK+++ + + IE+R++ + Sbjct: 147 VVKRRYSEFKSLRDNLLKLFPTLIIPPIPEKHSILSYLLNTINHSHEISIIEMRKRYFKM 206 Query: 443 FINRLASHPELK 478 F++ L + K Sbjct: 207 FLDDLIFQSDYK 218
>SNX41_ASHGO (Q759T1) Sorting nexin-41| Length = 603 Score = 41.2 bits (95), Expect = 0.002 Identities = 25/90 (27%), Positives = 44/90 (48%), Gaps = 7/90 (7%) Frame = +2 Query: 266 FEGAEKIVIRRYSDFEWLHDRLAEKYKGIFIPPLPEKNAVEKFRFSK-------EFIELR 424 +EG + V RRYS+F+ L LA + IPP+P K+ + ++ + IE R Sbjct: 151 YEGRQ--VTRRYSEFDSLRQALARLLPTVIIPPIPSKHPLIRYFLNPLNAENDIRIIEKR 208 Query: 425 RQALDLFINRLASHPELKQSEDLRTFLQAD 514 R+ L F+N ++++ + FL + Sbjct: 209 RRLLSRFLNNCHDITDIREHTVFQKFLNPE 238
>SNX15_HUMAN (Q9NRS6) Sorting nexin-15| Length = 342 Score = 40.4 bits (93), Expect = 0.003 Identities = 35/115 (30%), Positives = 54/115 (46%), Gaps = 4/115 (3%) Frame = +2 Query: 185 VTDPVKMGTGVQSY-ISYRVITKTNLPEFEGAEKIVIRRYSDFEWLHDRLAEKYKGIF-- 355 V+DP G Y ++ + I+K + PE + E +V +RYSDF LH LA ++ +F Sbjct: 15 VSDPRTHPKGYTEYKVTAQFISKKD-PE-DVKEVVVWKRYSDFRKLHGDLAYTHRNLFRR 72 Query: 356 IPPLPEKNAVEKF-RFSKEFIELRRQALDLFINRLASHPELKQSEDLRTFLQADE 517 + P + F RF IE RR+ + + P L S L+ F + E Sbjct: 73 LEEFPAFPRAQVFGRFEASVIEERRKGAEDLLRFTVHIPALNNSPQLKEFFRGGE 127
>SNX41_YEAST (Q04053) Sorting nexin-41| Length = 625 Score = 40.0 bits (92), Expect = 0.004 Identities = 23/83 (27%), Positives = 41/83 (49%), Gaps = 7/83 (8%) Frame = +2 Query: 287 VIRRYSDFEWLHDRLAEKYKGIFIPPLPEKNAVEKFRFS-------KEFIELRRQALDLF 445 +IRRYS+F L L I IPP+P K+++ K+ +S + I R++ L+ F Sbjct: 150 IIRRYSEFHSLRQSLTRLLPTIIIPPIPSKHSLLKYIWSPINAANDSKIISTRKKMLNSF 209 Query: 446 INRLASHPELKQSEDLRTFLQAD 514 ++ + E+ + FL + Sbjct: 210 LSNCLNIQEISNDIVFQKFLNPE 232
>ATG20_DEBHA (Q6BZE1) Autophagy-related protein 20| Length = 625 Score = 40.0 bits (92), Expect = 0.004 Identities = 33/109 (30%), Positives = 51/109 (46%), Gaps = 9/109 (8%) Frame = +2 Query: 221 SYISYRVITKTNLPEFEGAEKIVIRRYSDFEWLHDRLAEKYKGIFIPPLPEKNA-----V 385 S ++Y + L F+ IV RRYS+F+ L D L + + IPP+PEK+ + Sbjct: 97 SVVAYSI----ELSSFDDNRMIVKRRYSEFKSLRDNLQILFPTLVIPPIPEKHTLFTYLI 152 Query: 386 EKFRFSKE--FIELRRQALDLFINRLA--SHPELKQSEDLRTFLQADEE 520 SKE IE R++ F+ + S+ LK + FL + E Sbjct: 153 NSIDNSKELNIIETRKRCFANFLKDIIFDSNVALKSCVLVHKFLDPNYE 201
>PXK_RAT (Q4FZZ1) PX domain-containing protein kinase-like protein| (Modulator of Na,K-ATPase) (MONaKA) Length = 580 Score = 39.7 bits (91), Expect = 0.006 Identities = 29/110 (26%), Positives = 57/110 (51%) Frame = +2 Query: 176 SICVTDPVKMGTGVQSYISYRVITKTNLPEFEGAEKIVIRRYSDFEWLHDRLAEKYKGIF 355 ++ +T V+ +QS+ Y + + + + ++RRYSDF+ L++ L + G+ Sbjct: 17 TVPLTAAVEASQSLQSHTEYIIRVQRGISAENSWQ--IVRRYSDFDLLNNSL--QITGLS 72 Query: 356 IPPLPEKNAVEKFRFSKEFIELRRQALDLFINRLASHPELKQSEDLRTFL 505 + PLP K + +EFI R++ L ++N + ++ L E L+ FL Sbjct: 73 L-PLPPKKLIG--NMDREFIAERQKGLQNYLNVIMANHVLSNCELLKKFL 119
>SNX14_HUMAN (Q9Y5W7) Sorting nexin-14| Length = 886 Score = 39.7 bits (91), Expect = 0.006 Identities = 23/73 (31%), Positives = 36/73 (49%) Frame = +2 Query: 287 VIRRYSDFEWLHDRLAEKYKGIFIPPLPEKNAVEKFRFSKEFIELRRQALDLFINRLASH 466 V RRY +F L +L E + LP K + + EF++ +R+ ++ +L H Sbjct: 553 VYRRYLEFYVLESKLTEFHGAFPDAQLPSKRIIGPKNY--EFLKSKREEFQEYLQKLLQH 610 Query: 467 PELKQSEDLRTFL 505 PEL S+ L FL Sbjct: 611 PELSNSQLLADFL 623
>PXK_MOUSE (Q8BX57) PX domain-containing protein kinase-like protein| (Modulator of Na,K-ATPase) (MONaKA) Length = 582 Score = 39.7 bits (91), Expect = 0.006 Identities = 29/110 (26%), Positives = 57/110 (51%) Frame = +2 Query: 176 SICVTDPVKMGTGVQSYISYRVITKTNLPEFEGAEKIVIRRYSDFEWLHDRLAEKYKGIF 355 ++ +T V+ +QS+ Y + + + + ++RRYSDF+ L++ L + G+ Sbjct: 17 TVPLTAAVEASQSLQSHTEYIIRVQRGISAENSWQ--IVRRYSDFDLLNNSL--QITGLS 72 Query: 356 IPPLPEKNAVEKFRFSKEFIELRRQALDLFINRLASHPELKQSEDLRTFL 505 + PLP K + +EFI R++ L ++N + ++ L E L+ FL Sbjct: 73 L-PLPPKKLIG--NMDREFIAERQRGLQNYLNVIMANHVLSNCELLKKFL 119
>SNX27_HUMAN (Q96L92) Sorting nexin-27| Length = 435 Score = 39.3 bits (90), Expect = 0.007 Identities = 21/94 (22%), Positives = 45/94 (47%) Frame = +2 Query: 266 FEGAEKIVIRRYSDFEWLHDRLAEKYKGIFIPPLPEKNAVEKFRFSKEFIELRRQALDLF 445 + ++ +RY +F LH L ++ P LP K F S++ ++ RR+ L+ + Sbjct: 93 YMAGRQLCSKRYREFAILHQNLKREFANFTFPRLPGK---WPFSLSEQQLDARRRGLEEY 149 Query: 446 INRLASHPELKQSEDLRTFLQADEEKMDRARSYE 547 + ++ S + +S+ ++ FL +E + E Sbjct: 150 LEKVCSIRVIGESDIMQEFLSESDENYNGVSDVE 183
>SNX17_HUMAN (Q15036) Sorting nexin-17| Length = 470 Score = 39.3 bits (90), Expect = 0.007 Identities = 22/84 (26%), Positives = 42/84 (50%) Frame = +2 Query: 296 RYSDFEWLHDRLAEKYKGIFIPPLPEKNAVEKFRFSKEFIELRRQALDLFINRLASHPEL 475 RYS LH++L ++Y +P P K + F + +E RR+ L+ ++ + P L Sbjct: 36 RYSQLLGLHEQLRKEYGANVLPAFPPK---KLFSLTPAEVEQRREQLEKYMQAVRQDPLL 92 Query: 476 KQSEDLRTFLQADEEKMDRARSYE 547 SE +FL+ +++ + + E Sbjct: 93 GSSETFNSFLRRAQQETQQVPTEE 116
>PXK_HUMAN (Q7Z7A4) PX domain-containing protein kinase-like protein| (Modulator of Na,K-ATPase) (MONaKA) Length = 578 Score = 38.1 bits (87), Expect = 0.017 Identities = 30/110 (27%), Positives = 59/110 (53%) Frame = +2 Query: 176 SICVTDPVKMGTGVQSYISYRVITKTNLPEFEGAEKIVIRRYSDFEWLHDRLAEKYKGIF 355 ++ +T ++ +QS+ Y + + + E + +IV RRYSDF+ L++ L + G+ Sbjct: 17 TVPLTAAIEASQSLQSHTEYIIRVQRGI-SVENSWQIV-RRYSDFDLLNNSL--QIAGLS 72 Query: 356 IPPLPEKNAVEKFRFSKEFIELRRQALDLFINRLASHPELKQSEDLRTFL 505 + PLP K + +EFI R++ L ++N + ++ L E ++ FL Sbjct: 73 L-PLPPKKLIG--NMDREFIAERQKGLQNYLNVITTNHILSNCELVKKFL 119
>SNX25_HUMAN (Q9H3E2) Sorting nexin-25| Length = 538 Score = 37.7 bits (86), Expect = 0.022 Identities = 28/87 (32%), Positives = 42/87 (48%), Gaps = 3/87 (3%) Frame = +2 Query: 254 NLPEFEGAEK---IVIRRYSDFEWLHDRLAEKYKGIFIPPLPEKNAVEKFRFSKEFIELR 424 +L E G E V RR S+F+ LH +L+E + LP + + ++F+E Sbjct: 233 SLQEVGGVETKNWTVPRRLSEFQNLHRKLSECVPSLKKVQLPSLSKLPFKSIDQKFMEKS 292 Query: 425 RQALDLFINRLASHPELKQSEDLRTFL 505 + L+ F+ L S L QSE L FL Sbjct: 293 KNQLNKFLQNLLSDERLCQSEALYAFL 319
>ATG20_KLULA (Q6CNX6) Autophagy-related protein 20| Length = 636 Score = 37.7 bits (86), Expect = 0.022 Identities = 23/66 (34%), Positives = 36/66 (54%) Frame = +2 Query: 197 VKMGTGVQSYISYRVITKTNLPEFEGAEKIVIRRYSDFEWLHDRLAEKYKGIFIPPLPEK 376 V G G ++YI+Y + + + IV RRYSDFE L L + + IPP+PEK Sbjct: 173 VSEGQG-RTYIAYAI---------KYGDSIVKRRYSDFESLRKVLVKLFPISLIPPIPEK 222 Query: 377 NAVEKF 394 +++ + Sbjct: 223 QSLKSY 228
>ATG20_ASHGO (Q75B65) Autophagy-related protein 20| Length = 577 Score = 37.4 bits (85), Expect = 0.028 Identities = 22/66 (33%), Positives = 36/66 (54%) Frame = +2 Query: 197 VKMGTGVQSYISYRVITKTNLPEFEGAEKIVIRRYSDFEWLHDRLAEKYKGIFIPPLPEK 376 V G G +SYI+Y + + +++V RRYS+FE L L + + IPP+PEK Sbjct: 108 VSEGQG-RSYITYTISYR---------DRVVRRRYSEFESLRKILIKLFPMTLIPPIPEK 157 Query: 377 NAVEKF 394 ++ + Sbjct: 158 QSLTSY 163
>ATG20_YEAST (Q07528) Sorting nexin-42 (Autophagy-related protein 20) (Cytoplasm| to vacuole targeting protein 20) Length = 640 Score = 37.4 bits (85), Expect = 0.028 Identities = 24/66 (36%), Positives = 36/66 (54%) Frame = +2 Query: 197 VKMGTGVQSYISYRVITKTNLPEFEGAEKIVIRRYSDFEWLHDRLAEKYKGIFIPPLPEK 376 V G G ++YI+Y + +FE + V RRYSDFE L L + IPP+PEK Sbjct: 169 VSEGQG-RAYIAYVI-------QFENST--VQRRYSDFESLRSILIRLFPMTLIPPIPEK 218 Query: 377 NAVEKF 394 +++ + Sbjct: 219 QSIKNY 224
>SNX41_DEBHA (Q6BHN9) Sorting nexin-41| Length = 670 Score = 37.0 bits (84), Expect = 0.037 Identities = 20/37 (54%), Positives = 24/37 (64%) Frame = +2 Query: 293 RRYSDFEWLHDRLAEKYKGIFIPPLPEKNAVEKFRFS 403 RRYSDFE L D L + + I IPP+P KN F+FS Sbjct: 163 RRYSDFESLRDVLKKIFPLIIIPPIPPKN---YFKFS 196
>ATG20_CANAL (Q59TN9) Autophagy-related protein 20| Length = 407 Score = 36.2 bits (82), Expect = 0.063 Identities = 17/29 (58%), Positives = 20/29 (68%) Frame = +2 Query: 293 RRYSDFEWLHDRLAEKYKGIFIPPLPEKN 379 RRYSDFE L D L + + I IPP+P KN Sbjct: 204 RRYSDFESLRDVLTKIFPLIVIPPIPPKN 232
>ATG20_CANGA (Q6FR93) Autophagy-related protein 20| Length = 753 Score = 35.8 bits (81), Expect = 0.083 Identities = 16/37 (43%), Positives = 24/37 (64%) Frame = +2 Query: 284 IVIRRYSDFEWLHDRLAEKYKGIFIPPLPEKNAVEKF 394 +V RRYSDFE L L + + + IPP+PEK ++ + Sbjct: 315 MVRRRYSDFESLRSILVKLFPLMVIPPIPEKEGLKSY 351
>SNX13_HUMAN (Q9Y5W8) Sorting nexin-13 (RGS domain- and PHOX domain-containing| protein) (RGS-PX1) Length = 968 Score = 34.7 bits (78), Expect = 0.18 Identities = 21/72 (29%), Positives = 38/72 (52%), Gaps = 1/72 (1%) Frame = +2 Query: 293 RRYSDFEWLHDRLAEKYKGI-FIPPLPEKNAVEKFRFSKEFIELRRQALDLFINRLASHP 469 RRYSDF H R+ E+++ + I LP K ++F+E R++ L+ ++ L + Sbjct: 611 RRYSDFHDFHMRITEQFESLSSILKLPGKKTFN--NMDRDFLEKRKKDLNAYLQLLLAPE 668 Query: 470 ELKQSEDLRTFL 505 +K S L ++ Sbjct: 669 MMKASPALAHYV 680
>YK58_YEAST (P36158) Hypothetical 68.3 kDa protein in SIS2-MTD1 intergenic| region Length = 585 Score = 34.3 bits (77), Expect = 0.24 Identities = 18/43 (41%), Positives = 24/43 (55%), Gaps = 1/43 (2%) Frame = +2 Query: 278 EKIVIRRYSDFEWLHDRLAEKYKGIFIPPLPEKN-AVEKFRFS 403 EK + R +SDF WL+ +L + G IPP N VEK F+ Sbjct: 146 EKTIARAFSDFYWLYHQLQNNHWGKTIPPPTRSNILVEKDEFA 188
>SNX22_HUMAN (Q96L94) Sorting nexin-22| Length = 193 Score = 33.9 bits (76), Expect = 0.31 Identities = 21/59 (35%), Positives = 29/59 (49%) Frame = +2 Query: 272 GAEKIVIRRYSDFEWLHDRLAEKYKGIFIPPLPEKNAVEKFRFSKEFIELRRQALDLFI 448 G V RRYS+F LH R+ + YK +P P K + +E RRQ L+ +I Sbjct: 35 GRRHTVPRRYSEFHALHKRIKKLYK---VPDFPSKRLP---NWRTRGLEQRRQGLEAYI 87
>YTDK_CAEEL (Q19532) Hypothetical protein F17H10.3 in chromosome X| Length = 540 Score = 32.0 bits (71), Expect = 1.2 Identities = 17/59 (28%), Positives = 29/59 (49%) Frame = +2 Query: 299 YSDFEWLHDRLAEKYKGIFIPPLPEKNAVEKFRFSKEFIELRRQALDLFINRLASHPEL 475 Y E + + +++YKG PE A + F+ + I+ RRQ + + L HPE+ Sbjct: 107 YEFAELIKQKFSQRYKG------PEFPAKKLFKLDPKAIDERRQKITKYFQALVQHPEV 159
>SNX20_MOUSE (Q9D2Y5) Sorting nexin-20| Length = 313 Score = 31.6 bits (70), Expect = 1.6 Identities = 29/104 (27%), Positives = 47/104 (45%), Gaps = 3/104 (2%) Frame = +2 Query: 215 VQSYISYRVITKTNLPEFEGAEKIVIRRYSDFEWLHDRLAEKYKGIFIPPLPEKNAVEK- 391 V ++ Y+V+ F+ + +V RRYSDFE L L ++ F P L + K Sbjct: 87 VSKFVMYQVVV-IQTGSFDSDKAVVERRYSDFERLQKALLKR----FGPELEDVAFPRKR 141 Query: 392 --FRFSKEFIELRRQALDLFINRLASHPELKQSEDLRTFLQADE 517 S E I RR+ L ++ L + +++S + FL E Sbjct: 142 LTGNLSAETICERRRELREYLRLLYAVRAVRRSREFLDFLTRPE 185
>SNX24_RAT (Q5U2S5) Sorting nexing 24| Length = 169 Score = 30.8 bits (68), Expect = 2.7 Identities = 20/59 (33%), Positives = 30/59 (50%) Frame = +2 Query: 272 GAEKIVIRRYSDFEWLHDRLAEKYKGIFIPPLPEKNAVEKFRFSKEFIELRRQALDLFI 448 G + V +RYS+F LH +L + K IP +N V K +E RRQ L+ ++ Sbjct: 30 GRKHFVEKRYSEFHALHKKLKKCIKTPEIPSKHVRNWVPK------VLEQRRQGLETYL 82
>SNX24_MOUSE (Q9CRB0) Sorting nexin-24| Length = 169 Score = 30.8 bits (68), Expect = 2.7 Identities = 20/59 (33%), Positives = 30/59 (50%) Frame = +2 Query: 272 GAEKIVIRRYSDFEWLHDRLAEKYKGIFIPPLPEKNAVEKFRFSKEFIELRRQALDLFI 448 G + V +RYS+F LH +L + K IP +N V K +E RRQ L+ ++ Sbjct: 30 GRKHFVEKRYSEFHALHKKLKKCIKTPEIPSKHVRNWVPK------VLEQRRQGLETYL 82
>SNX24_HUMAN (Q9Y343) Sorting nexin-24| Length = 169 Score = 30.8 bits (68), Expect = 2.7 Identities = 20/59 (33%), Positives = 30/59 (50%) Frame = +2 Query: 272 GAEKIVIRRYSDFEWLHDRLAEKYKGIFIPPLPEKNAVEKFRFSKEFIELRRQALDLFI 448 G + V +RYS+F LH +L + K IP +N V K +E RRQ L+ ++ Sbjct: 30 GRKHFVEKRYSEFHALHKKLKKCIKTPEIPSKHVRNWVPK------VLEQRRQGLETYL 82
>VAM7_YEAST (P32912) Vacuolar morphogenesis protein VAM7| Length = 316 Score = 30.4 bits (67), Expect = 3.5 Identities = 29/98 (29%), Positives = 48/98 (48%), Gaps = 9/98 (9%) Frame = +2 Query: 281 KIVIRRYSDFEWLHDRLAEKYKGIFIP-PLPEKNAVEKFRFSK-----EFIELRRQALDL 442 K + +RYS+F L RL E+ G IP PEK V R+ + E I+ RR L+ Sbjct: 36 KRLYKRYSEFWKLKTRL-ERDVGSTIPYDFPEKPGVLDRRWQRRYDDPEMIDERRIGLER 94 Query: 443 FINRLAS---HPELKQSEDLRTFLQADEEKMDRARSYE 547 F+N L + + ++ + FLQ + + + +S + Sbjct: 95 FLNELYNDRFDSRWRDTKIAQDFLQLSKPNVSQEKSQQ 132
>INCE_HUMAN (Q9NQS7) Inner centromere protein| Length = 923 Score = 30.0 bits (66), Expect = 4.5 Identities = 18/49 (36%), Positives = 26/49 (53%) Frame = +2 Query: 371 EKNAVEKFRFSKEFIELRRQALDLFINRLASHPELKQSEDLRTFLQADE 517 E+ +E R +E +LRRQ ++ R +LK+ E LR LQA E Sbjct: 538 ERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARE 586
>PROW_ECOLI (P14176) Glycine betaine/L-proline transport system permease| protein proW Length = 354 Score = 29.6 bits (65), Expect = 5.9 Identities = 13/35 (37%), Positives = 14/35 (40%) Frame = -1 Query: 219 WTPVPILTGSVTQIDRNGAPAAAPGDRGLCDWLLS 115 W P + D G P AP D G DWL S Sbjct: 8 WDTTPAADSAAQSADAWGTPTTAPTDGGGADWLTS 42
>YLB9_CAEEL (P46583) Hypothetical protein C34E10.9| Length = 122 Score = 29.3 bits (64), Expect = 7.8 Identities = 15/37 (40%), Positives = 19/37 (51%) Frame = +2 Query: 359 PPLPEKNAVEKFRFSKEFIELRRQALDLFINRLASHP 469 PP P +N FS EF+E RR+ + RLA P Sbjct: 23 PPTPTRNTQGGHGFSAEFLEYRRRRQERHTVRLAKLP 59 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 62,419,266 Number of Sequences: 219361 Number of extensions: 1094233 Number of successful extensions: 3504 Number of sequences better than 10.0: 87 Number of HSP's better than 10.0 without gapping: 3336 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 3451 length of database: 80,573,946 effective HSP length: 105 effective length of database: 57,541,041 effective search space used: 4488201198 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)