Clone Name | bart15d07 |
---|---|
Clone Library Name | barley_pub |
>SAPK5_ORYSA (Q7XKA8) Serine/threonine-protein kinase SAPK5 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 5) Length = 370 Score = 222 bits (565), Expect = 7e-58 Identities = 106/117 (90%), Positives = 113/117 (96%) Frame = +1 Query: 223 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHRSLRHPNI 402 M+KYEPVREIG+GNFGVAKLMRN++TRELVAMKFIERG RIDENVFREIVNHRSLRHPNI Sbjct: 1 MEKYEPVREIGAGNFGVAKLMRNKETRELVAMKFIERGNRIDENVFREIVNHRSLRHPNI 60 Query: 403 IRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCHAM 573 IRFKEVV+T HL IVMEYAAGGELFERIC+AGRFHEDEARYFFQQLVCGVS+CHAM Sbjct: 61 IRFKEVVVTGRHLAIVMEYAAGGELFERICEAGRFHEDEARYFFQQLVCGVSYCHAM 117
>SAPK4_ORYSA (Q5N942) Serine/threonine-protein kinase SAPK4 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 4) Length = 360 Score = 210 bits (535), Expect = 2e-54 Identities = 98/117 (83%), Positives = 111/117 (94%) Frame = +1 Query: 223 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHRSLRHPNI 402 M+KYE VR+IGSGNFGVA+LMRNR+TRELVA+K IERG+RIDENV+REI+NHRSLRHPNI Sbjct: 1 MEKYEAVRDIGSGNFGVARLMRNRETRELVAVKCIERGHRIDENVYREIINHRSLRHPNI 60 Query: 403 IRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCHAM 573 IRFKEV+LTPTHL IVME+AAGGELF+RICD GRF EDEARYFFQQL+CGVS+CH M Sbjct: 61 IRFKEVILTPTHLMIVMEFAAGGELFDRICDRGRFSEDEARYFFQQLICGVSYCHHM 117
>SAPK6_ORYSA (Q6ZI44) Serine/threonine-protein kinase SAPK6 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 6) Length = 365 Score = 204 bits (520), Expect = 1e-52 Identities = 95/117 (81%), Positives = 109/117 (93%) Frame = +1 Query: 223 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHRSLRHPNI 402 M+KYE +++IGSGNFGVA+LMRNR+T+ELVAMK+I RG +IDENV REI+NHRSLRHPNI Sbjct: 1 MEKYELLKDIGSGNFGVARLMRNRETKELVAMKYIPRGLKIDENVAREIINHRSLRHPNI 60 Query: 403 IRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCHAM 573 IRFKEVVLTPTHL IVMEYAAGGELF+RIC AGRF EDE+RYFFQQL+CGVS+CH M Sbjct: 61 IRFKEVVLTPTHLAIVMEYAAGGELFDRICSAGRFSEDESRYFFQQLICGVSYCHFM 117
>SAPK7_ORYSA (Q7XQP4) Serine/threonine-protein kinase SAPK7 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 7) Length = 359 Score = 201 bits (512), Expect = 9e-52 Identities = 92/117 (78%), Positives = 110/117 (94%) Frame = +1 Query: 223 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHRSLRHPNI 402 M++YE +++IG+GNFGVA+LMRN++T+ELVAMK+I RG +IDENV REI+NHRSLRHPNI Sbjct: 1 MERYELLKDIGAGNFGVARLMRNKETKELVAMKYIPRGLKIDENVAREIINHRSLRHPNI 60 Query: 403 IRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCHAM 573 IRFKEVV+TPTHL IVMEYAAGGELF+RIC+AGRF EDEARYFFQQL+CGVS+CH M Sbjct: 61 IRFKEVVVTPTHLAIVMEYAAGGELFDRICNAGRFSEDEARYFFQQLICGVSYCHFM 117
>ASK1_ARATH (P43291) Serine/threonine-protein kinase ASK1 (EC 2.7.11.1)| Length = 363 Score = 199 bits (506), Expect = 5e-51 Identities = 94/117 (80%), Positives = 108/117 (92%) Frame = +1 Query: 223 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHRSLRHPNI 402 MDKYE V++IG+GNFGVA+LM+ ++++ELVAMK+IERG +IDENV REI+NHRSLRHPNI Sbjct: 1 MDKYELVKDIGAGNFGVARLMKVKNSKELVAMKYIERGPKIDENVAREIINHRSLRHPNI 60 Query: 403 IRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCHAM 573 IRFKEVVLTPTHL I MEYAAGGELFERIC AGRF EDEARYFFQQL+ GVS+CHAM Sbjct: 61 IRFKEVVLTPTHLAIAMEYAAGGELFERICSAGRFSEDEARYFFQQLISGVSYCHAM 117
>ASK2_ARATH (P43292) Serine/threonine-protein kinase ASK2 (EC 2.7.11.1)| Length = 353 Score = 197 bits (501), Expect = 2e-50 Identities = 88/117 (75%), Positives = 109/117 (93%) Frame = +1 Query: 223 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHRSLRHPNI 402 MDKY+ V+++G+GNFGVA+L+R++DT+ELVAMK+IERG +IDENV REI+NHRSL+HPNI Sbjct: 1 MDKYDVVKDLGAGNFGVARLLRHKDTKELVAMKYIERGRKIDENVAREIINHRSLKHPNI 60 Query: 403 IRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCHAM 573 IRFKEV+LTPTHL IVMEYA+GGELF+RIC AGRF E EARYFFQQL+CGV +CH++ Sbjct: 61 IRFKEVILTPTHLAIVMEYASGGELFDRICTAGRFSEAEARYFFQQLICGVDYCHSL 117
>SAPK9_ORYSA (Q75V57) Serine/threonine-protein kinase SAPK9 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 9) Length = 361 Score = 195 bits (495), Expect = 9e-50 Identities = 91/116 (78%), Positives = 107/116 (92%) Frame = +1 Query: 226 DKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHRSLRHPNII 405 D+YE V+EIGSGNFGVA+LMRNR + +LVA+K+I+RG +IDENV REI+NHRSLRHPNII Sbjct: 20 DRYELVKEIGSGNFGVARLMRNRASGDLVAVKYIDRGEKIDENVQREIINHRSLRHPNII 79 Query: 406 RFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCHAM 573 RFKEV+LTPTHL IVMEYA+GGELFERIC AGRF EDEAR+FFQQL+ GVS+CH+M Sbjct: 80 RFKEVILTPTHLAIVMEYASGGELFERICSAGRFSEDEARFFFQQLISGVSYCHSM 135
>SAPK2_ORYSA (Q84TC6) Serine/threonine-protein kinase SAPK2 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 2) Length = 339 Score = 194 bits (493), Expect = 1e-49 Identities = 91/117 (77%), Positives = 107/117 (91%) Frame = +1 Query: 223 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHRSLRHPNI 402 M++YE +++IGSGNFGVAKL+R+ T+EL A+KFIERG +IDENV REI+NHRSLRHPNI Sbjct: 1 MERYEVIKDIGSGNFGVAKLVRDVRTKELFAVKFIERGQKIDENVQREIMNHRSLRHPNI 60 Query: 403 IRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCHAM 573 +RFKEVVLTPTHL IVMEYAAGGELFERIC AGRF EDEAR+FFQQL+ GVS+CH+M Sbjct: 61 VRFKEVVLTPTHLAIVMEYAAGGELFERICSAGRFSEDEARFFFQQLISGVSYCHSM 117
>SAPKA_ORYSA (Q75H77) Serine/threonine-protein kinase SAPK10 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 10) Length = 362 Score = 193 bits (491), Expect = 3e-49 Identities = 91/116 (78%), Positives = 107/116 (92%) Frame = +1 Query: 226 DKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHRSLRHPNII 405 D+YE VR+IGSGNFGVA+LMR+R +LVA+K+IERG +IDENV REI+NHRSLRHPNII Sbjct: 21 DRYELVRDIGSGNFGVARLMRSRADGQLVAVKYIERGDKIDENVQREIINHRSLRHPNII 80 Query: 406 RFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCHAM 573 RFKEV+LTPTHL IVMEYA+GGELFERIC+AGRF EDEAR+FFQQL+ GVS+CH+M Sbjct: 81 RFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLISGVSYCHSM 136
>SAPK8_ORYSA (Q7Y0B9) Serine/threonine-protein kinase SAPK8 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 8) Length = 371 Score = 190 bits (483), Expect = 2e-48 Identities = 90/116 (77%), Positives = 105/116 (90%) Frame = +1 Query: 226 DKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHRSLRHPNII 405 D+YE VR+IGSGNFGVA+LMR+R T ELVA+K+IERG +ID+NV REI+NHRSL+HPNII Sbjct: 31 DRYELVRDIGSGNFGVARLMRDRRTMELVAVKYIERGEKIDDNVQREIINHRSLKHPNII 90 Query: 406 RFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCHAM 573 RFKEV+LTPTHL IVMEYA+GGELFERIC RF EDEARYFFQQL+ GVS+CH+M Sbjct: 91 RFKEVILTPTHLAIVMEYASGGELFERICKNVRFSEDEARYFFQQLISGVSYCHSM 146
>SAPK1_ORYSA (Q75LR7) Serine/threonine-protein kinase SAPK1 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 1) Length = 342 Score = 189 bits (481), Expect = 4e-48 Identities = 90/117 (76%), Positives = 106/117 (90%) Frame = +1 Query: 223 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHRSLRHPNI 402 M++YE +R+IGSGNFGVAKL+R+ T L A+KFIERG +IDE+V REI+NHRSL+HPNI Sbjct: 1 MERYEVMRDIGSGNFGVAKLVRDVATNHLFAVKFIERGLKIDEHVQREIMNHRSLKHPNI 60 Query: 403 IRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCHAM 573 IRFKEVVLTPTHL IVMEYAAGGELFERIC+AGRF EDEAR+FFQQL+ GVS+CH+M Sbjct: 61 IRFKEVVLTPTHLAIVMEYAAGGELFERICNAGRFSEDEARFFFQQLISGVSYCHSM 117
>SAPK3_ORYSA (Q75V63) Serine/threonine-protein kinase SAPK3 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 3) (Protein kinase REK) Length = 334 Score = 188 bits (478), Expect = 8e-48 Identities = 86/116 (74%), Positives = 107/116 (92%) Frame = +1 Query: 226 DKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHRSLRHPNII 405 ++YE ++E+G+GNFGVA+L+R++ ++ELVA+K+IERG +IDENV REI+NHRSLRHPNII Sbjct: 3 ERYEALKELGAGNFGVARLVRDKRSKELVAVKYIERGKKIDENVQREIINHRSLRHPNII 62 Query: 406 RFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCHAM 573 RFKEV LTPTHL IVMEYAAGGELFE+IC AGRF EDEARYFFQQL+ GVS+CH++ Sbjct: 63 RFKEVCLTPTHLAIVMEYAAGGELFEQICTAGRFSEDEARYFFQQLISGVSYCHSL 118
>AAIP_WHEAT (Q02066) Abscisic acid-inducible protein kinase (EC 2.7.11.1)| (Fragment) Length = 332 Score = 175 bits (443), Expect = 9e-44 Identities = 82/107 (76%), Positives = 98/107 (91%) Frame = +1 Query: 253 GSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHRSLRHPNIIRFKEVVLTP 432 GSGNFGVAKL+R+ T+E A+KFIERG++IDE+V REI+NHRSL+HPNIIRFKEVVLTP Sbjct: 1 GSGNFGVAKLVRDVRTKEHFAVKFIERGHKIDEHVQREIMNHRSLKHPNIIRFKEVVLTP 60 Query: 433 THLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCHAM 573 THL IVMEYA+GGELF+RIC+AGRF EDE R+FFQQL+ GVS+CH+M Sbjct: 61 THLAIVMEYASGGELFQRICNAGRFSEDEGRFFFQQLISGVSYCHSM 107
>KIN10_ARATH (Q38997) SNF1-related protein kinase catalytic alpha subunit KIN10| (EC 2.7.11.1) (AKIN10) (AKIN alpha2) Length = 535 Score = 99.4 bits (246), Expect = 7e-21 Identities = 55/127 (43%), Positives = 74/127 (58%), Gaps = 4/127 (3%) Frame = +1 Query: 199 SRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIER----GYRIDENVFRE 366 SR S + Y+ R +G G+FG K+ + T VA+K + R ++E V RE Sbjct: 31 SRSGVESILPNYKLGRTLGIGSFGRVKIAEHALTGHKVAIKILNRRKIKNMEMEEKVRRE 90 Query: 367 IVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLV 546 I R HP+IIR EV+ TPT + +VMEY GELF+ I + GR EDEAR FFQQ++ Sbjct: 91 IKILRLFMHPHIIRLYEVIETPTDIYLVMEYVNSGELFDYIVEKGRLQEDEARNFFQQII 150 Query: 547 CGVSFCH 567 GV +CH Sbjct: 151 SGVEYCH 157
>CPK24_ARATH (Q9LDI3) CBL-interacting serine/threonine-protein kinase 24 (EC| 2.7.11.1) (SNF1-related kinase 3.11) (SALT OVERLY SENSITIVE 2 protein) Length = 446 Score = 99.0 bits (245), Expect = 9e-21 Identities = 52/117 (44%), Positives = 72/117 (61%), Gaps = 4/117 (3%) Frame = +1 Query: 229 KYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGY----RIDENVFREIVNHRSLRHP 396 KYE R IG G F K RN DT + VA+K + + R+ + + REI + +RHP Sbjct: 10 KYEVGRTIGEGTFAKVKFARNTDTGDNVAIKIMAKSTILKNRMVDQIKREISIMKIVRHP 69 Query: 397 NIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCH 567 NI+R EV+ +P+ + IV+E+ GGELF+RI GR E E+R +FQQLV V+ CH Sbjct: 70 NIVRLYEVLASPSKIYIVLEFVTGGELFDRIVHKGRLEESESRKYFQQLVDAVAHCH 126
>CIPK1_ORYSA (Q6X4A2) CIPK-like protein 1 (EC 2.7.11.1) (OsCK1)| Length = 449 Score = 95.5 bits (236), Expect = 9e-20 Identities = 48/118 (40%), Positives = 72/118 (61%), Gaps = 4/118 (3%) Frame = +1 Query: 229 KYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERG----YRIDENVFREIVNHRSLRHP 396 KYE R IG G F + +N + E VA+K +++ +R+ E + REI + ++HP Sbjct: 19 KYELGRTIGEGTFAKVRFAKNTENDEPVAIKILDKEKVQKHRLVEQIRREICTMKLVKHP 78 Query: 397 NIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCHA 570 N++R EV+ + + IV+EY GGELFE I GR E+EAR +FQQL+ V +CH+ Sbjct: 79 NVVRLFEVMGSKARIFIVLEYVTGGELFEIIATNGRLKEEEARKYFQQLINAVDYCHS 136
>CIPK1_ARATH (Q8RWC9) CBL-interacting serine/threonine-protein kinase 1 (EC| 2.7.11.1) (SOS2-like protein kinase PKS13) (SNF1-related kinase 3.16) Length = 444 Score = 92.8 bits (229), Expect = 6e-19 Identities = 48/134 (35%), Positives = 75/134 (55%), Gaps = 4/134 (2%) Frame = +1 Query: 181 RKTSNRSRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDEN-- 354 R+ + + + KYE R +G GNFG K ++ + A+K I++ D N Sbjct: 3 RRQEEEKKAEKGMRLGKYELGRTLGEGNFGKVKFAKDTVSGHSFAVKIIDKSRIADLNFS 62 Query: 355 --VFREIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARY 528 + REI + L+HP+I+R EV+ + T + +VME GGELF+RI G+ E + R Sbjct: 63 LQIKREIRTLKMLKHPHIVRLHEVLASKTKINMVMELVTGGELFDRIVSNGKLTETDGRK 122 Query: 529 FFQQLVCGVSFCHA 570 FQQL+ G+S+CH+ Sbjct: 123 MFQQLIDGISYCHS 136
>SNF1_SCHPO (O74536) SNF1-like protein kinase ssp2 (EC 2.7.11.1)| Length = 576 Score = 92.8 bits (229), Expect = 6e-19 Identities = 51/114 (44%), Positives = 73/114 (64%), Gaps = 5/114 (4%) Frame = +1 Query: 241 VRE-IGSGNFGVAKLMRNRDTRELVAMKFIERGYR----IDENVFREIVNHRSLRHPNII 405 +RE +G G+FG KL + T++ VA+KFI R + V REI + LRHP+II Sbjct: 36 IRETLGEGSFGKVKLATHYKTQQKVALKFISRQLLKKSDMHMRVEREISYLKLLRHPHII 95 Query: 406 RFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCH 567 + +V+ TPT + +V+EYA GGELF+ I + R EDE R FFQQ++C + +CH Sbjct: 96 KLYDVITTPTDIVMVIEYA-GGELFDYIVEKKRMTEDEGRRFFQQIICAIEYCH 148
>KIN11_ARATH (P92958) SNF1-related protein kinase catalytic alpha subunit KIN11| (EC 2.7.11.1) (AKIN11) (AKIN alpha1) Length = 512 Score = 91.3 bits (225), Expect = 2e-18 Identities = 49/119 (41%), Positives = 70/119 (58%), Gaps = 4/119 (3%) Frame = +1 Query: 223 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIER----GYRIDENVFREIVNHRSLR 390 + Y+ + +G G+FG K+ + T VA+K + R ++E V REI R Sbjct: 17 LPNYKLGKTLGIGSFGKVKIAEHVVTGHKVAIKILNRRKIKNMEMEEKVRREIKILRLFM 76 Query: 391 HPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCH 567 HP+IIR EV+ T + + +VMEY GELF+ I + GR EDEAR FFQQ++ GV +CH Sbjct: 77 HPHIIRQYEVIETTSDIYVVMEYVKSGELFDYIVEKGRLQEDEARNFFQQIISGVEYCH 135
>MARK4_MOUSE (Q8CIP4) MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1)| Length = 752 Score = 89.7 bits (221), Expect = 5e-18 Identities = 52/140 (37%), Positives = 77/140 (55%), Gaps = 3/140 (2%) Frame = +1 Query: 157 ASREIATHRKTSNRSRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERG 336 +SR + + S S E+ + Y +R IG GNF KL R+ T VA+K I++ Sbjct: 34 SSRSLGARCRNSIASCPEEQPHVGNYRLLRTIGKGNFAKVKLARHILTGREVAIKIIDKT 93 Query: 337 YRID---ENVFREIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRF 507 + +FRE+ + L HPNI++ EV+ T L +VMEYA+ GE+F+ + GR Sbjct: 94 QLNPSSLQKLFREVRIMKGLNHPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRM 153 Query: 508 HEDEARYFFQQLVCGVSFCH 567 E EAR F+Q+V V +CH Sbjct: 154 KEKEARAKFRQIVSAVHYCH 173
>MARK4_HUMAN (Q96L34) MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase-like 1) Length = 752 Score = 89.7 bits (221), Expect = 5e-18 Identities = 52/140 (37%), Positives = 77/140 (55%), Gaps = 3/140 (2%) Frame = +1 Query: 157 ASREIATHRKTSNRSRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERG 336 +SR + + S S E+ + Y +R IG GNF KL R+ T VA+K I++ Sbjct: 34 SSRSLGARCRNSIASCPEEQPHVGNYRLLRTIGKGNFAKVKLARHILTGREVAIKIIDKT 93 Query: 337 YRID---ENVFREIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRF 507 + +FRE+ + L HPNI++ EV+ T L +VMEYA+ GE+F+ + GR Sbjct: 94 QLNPSSLQKLFREVRIMKGLNHPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRM 153 Query: 508 HEDEARYFFQQLVCGVSFCH 567 E EAR F+Q+V V +CH Sbjct: 154 KEKEARAKFRQIVSAVHYCH 173
>AAPK1_PONPY (Q5RDH5) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMPK alpha-1 chain) Length = 550 Score = 89.4 bits (220), Expect = 7e-18 Identities = 48/131 (36%), Positives = 74/131 (56%), Gaps = 4/131 (3%) Frame = +1 Query: 187 TSNRSRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIER----GYRIDEN 354 T+ + + R + Y +G G FG K+ ++ T VA+K + R + Sbjct: 3 TAEKQKHDGRVRIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGK 62 Query: 355 VFREIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFF 534 + REI N + RHP+II+ +V+ TP+ + +VMEY +GGELF+ IC GR E E+R F Sbjct: 63 IRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLF 122 Query: 535 QQLVCGVSFCH 567 QQ++ GV +CH Sbjct: 123 QQILSGVDYCH 133
>AAPK1_HUMAN (Q13131) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMPK alpha-1 chain) Length = 550 Score = 89.4 bits (220), Expect = 7e-18 Identities = 48/131 (36%), Positives = 74/131 (56%), Gaps = 4/131 (3%) Frame = +1 Query: 187 TSNRSRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIER----GYRIDEN 354 T+ + + R + Y +G G FG K+ ++ T VA+K + R + Sbjct: 3 TAEKQKHDGRVKIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGK 62 Query: 355 VFREIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFF 534 + REI N + RHP+II+ +V+ TP+ + +VMEY +GGELF+ IC GR E E+R F Sbjct: 63 IRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLF 122 Query: 535 QQLVCGVSFCH 567 QQ++ GV +CH Sbjct: 123 QQILSGVDYCH 133
>AAPK1_RAT (P54645) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMPK alpha-1 chain) Length = 548 Score = 89.0 bits (219), Expect = 9e-18 Identities = 45/110 (40%), Positives = 67/110 (60%), Gaps = 4/110 (3%) Frame = +1 Query: 250 IGSGNFGVAKLMRNRDTRELVAMKFIER----GYRIDENVFREIVNHRSLRHPNIIRFKE 417 +G G FG K+ ++ T VA+K + R + + REI N + RHP+II+ + Sbjct: 22 LGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQ 81 Query: 418 VVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCH 567 V+ TP+ + +VMEY +GGELF+ IC GR E E+R FQQ++ GV +CH Sbjct: 82 VISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCH 131
>AAPK1_MOUSE (Q5EG47) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMPK alpha-1 chain) Length = 548 Score = 89.0 bits (219), Expect = 9e-18 Identities = 45/110 (40%), Positives = 67/110 (60%), Gaps = 4/110 (3%) Frame = +1 Query: 250 IGSGNFGVAKLMRNRDTRELVAMKFIER----GYRIDENVFREIVNHRSLRHPNIIRFKE 417 +G G FG K+ ++ T VA+K + R + + REI N + RHP+II+ + Sbjct: 22 LGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQ 81 Query: 418 VVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCH 567 V+ TP+ + +VMEY +GGELF+ IC GR E E+R FQQ++ GV +CH Sbjct: 82 VISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCH 131
>MARK2_HUMAN (Q7KZI7) Serine/threonine-protein kinase MARK2 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 2) (ELKL motif kinase) (EMK1) (PAR1 homolog) Length = 788 Score = 88.6 bits (218), Expect = 1e-17 Identities = 53/143 (37%), Positives = 81/143 (56%), Gaps = 3/143 (2%) Frame = +1 Query: 148 SAPASREIATHRKTSNRSRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFI 327 S P+S+ + S S + E+ + Y ++ IG GNF KL R+ T + VA+K I Sbjct: 26 SKPSSKSNMIRGRNSATSAD-EQPHIGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKII 84 Query: 328 ERGYRID---ENVFREIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDA 498 ++ + +FRE+ + L HPNI++ EV+ T L +VMEYA+GGE+F+ + Sbjct: 85 DKTQLNSSSLQKLFREVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAH 144 Query: 499 GRFHEDEARYFFQQLVCGVSFCH 567 GR E EAR F+Q+V V +CH Sbjct: 145 GRMKEKEARAKFRQIVSAVQYCH 167
>MARK2_RAT (O08679) Serine/threonine-protein kinase MARK2 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 2) (ELKL Motif Kinase) (EMK1) Length = 722 Score = 88.6 bits (218), Expect = 1e-17 Identities = 53/143 (37%), Positives = 81/143 (56%), Gaps = 3/143 (2%) Frame = +1 Query: 148 SAPASREIATHRKTSNRSRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFI 327 S P+S+ + S S + E+ + Y ++ IG GNF KL R+ T + VA+K I Sbjct: 26 SKPSSKSNMLRGRNSATSAD-EQPHIGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKII 84 Query: 328 ERGYRID---ENVFREIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDA 498 ++ + +FRE+ + L HPNI++ EV+ T L +VMEYA+GGE+F+ + Sbjct: 85 DKTQLNSSSLQKLFREVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAH 144 Query: 499 GRFHEDEARYFFQQLVCGVSFCH 567 GR E EAR F+Q+V V +CH Sbjct: 145 GRMKEKEARAKFRQIVSAVQYCH 167
>AAPK2_RAT (Q09137) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMPK alpha-2 chain) Length = 552 Score = 87.8 bits (216), Expect = 2e-17 Identities = 46/110 (41%), Positives = 65/110 (59%), Gaps = 4/110 (3%) Frame = +1 Query: 250 IGSGNFGVAKLMRNRDTRELVAMKFIER----GYRIDENVFREIVNHRSLRHPNIIRFKE 417 +G G FG K+ ++ T VA+K + R + + REI N + RHP+II+ + Sbjct: 22 LGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPHIIKLYQ 81 Query: 418 VVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCH 567 V+ TPT +VMEY +GGELF+ IC GR E EAR FQQ++ V +CH Sbjct: 82 VISTPTDFFMVMEYVSGGELFDYICKHGRVEEVEARRLFQQILSAVDYCH 131
>AAPK2_PONPY (Q5RD00) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMPK alpha-2 chain) Length = 552 Score = 87.8 bits (216), Expect = 2e-17 Identities = 46/110 (41%), Positives = 65/110 (59%), Gaps = 4/110 (3%) Frame = +1 Query: 250 IGSGNFGVAKLMRNRDTRELVAMKFIER----GYRIDENVFREIVNHRSLRHPNIIRFKE 417 +G G FG K+ ++ T VA+K + R + + REI N + RHP+II+ + Sbjct: 22 LGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPHIIKLYQ 81 Query: 418 VVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCH 567 V+ TPT +VMEY +GGELF+ IC GR E EAR FQQ++ V +CH Sbjct: 82 VISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCH 131
>AAPK2_PIG (Q28948) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMPK alpha-2 chain) Length = 552 Score = 87.8 bits (216), Expect = 2e-17 Identities = 46/110 (41%), Positives = 65/110 (59%), Gaps = 4/110 (3%) Frame = +1 Query: 250 IGSGNFGVAKLMRNRDTRELVAMKFIER----GYRIDENVFREIVNHRSLRHPNIIRFKE 417 +G G FG K+ ++ T VA+K + R + + REI N + RHP+II+ + Sbjct: 22 LGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPHIIKLYQ 81 Query: 418 VVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCH 567 V+ TPT +VMEY +GGELF+ IC GR E EAR FQQ++ V +CH Sbjct: 82 VISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCH 131
>AAPK2_HUMAN (P54646) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMPK alpha-2 chain) Length = 552 Score = 87.8 bits (216), Expect = 2e-17 Identities = 46/110 (41%), Positives = 65/110 (59%), Gaps = 4/110 (3%) Frame = +1 Query: 250 IGSGNFGVAKLMRNRDTRELVAMKFIER----GYRIDENVFREIVNHRSLRHPNIIRFKE 417 +G G FG K+ ++ T VA+K + R + + REI N + RHP+II+ + Sbjct: 22 LGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPHIIKLYQ 81 Query: 418 VVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCH 567 V+ TPT +VMEY +GGELF+ IC GR E EAR FQQ++ V +CH Sbjct: 82 VISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCH 131
>MARK2_MOUSE (Q05512) Serine/threonine-protein kinase MARK2 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 2) (ELKL Motif Kinase) (EMK1) Length = 776 Score = 87.8 bits (216), Expect = 2e-17 Identities = 53/143 (37%), Positives = 81/143 (56%), Gaps = 3/143 (2%) Frame = +1 Query: 148 SAPASREIATHRKTSNRSRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFI 327 S P+S+ + S S + E+ + Y ++ IG GNF KL R+ T + VA+K I Sbjct: 26 SKPSSKSNMLRGRNSATSAD-EQPHIGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKII 84 Query: 328 ERGYRID---ENVFREIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDA 498 ++ + +FRE+ + L HPNI++ EV+ T L +VMEYA+GGE+F+ + Sbjct: 85 DKTQLNSSSLQKLFREVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAH 144 Query: 499 GRFHEDEARYFFQQLVCGVSFCH 567 GR E EAR F+Q+V V +CH Sbjct: 145 GRMKEKEARAKFRQIVLHVQYCH 167
>SN1L1_MOUSE (Q60670) Serine/threonine-protein kinase SNF1-like kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase SNF1LK) (HRT-20) (Myocardial SNF1-like kinase) Length = 779 Score = 86.7 bits (213), Expect = 4e-17 Identities = 47/116 (40%), Positives = 70/116 (60%), Gaps = 4/116 (3%) Frame = +1 Query: 232 YEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRID----ENVFREIVNHRSLRHPN 399 Y+ R +G GNF V KL R+R T+ VA+K I++ R+D E ++RE+ + L HPN Sbjct: 27 YDVERTLGKGNFAVVKLARHRVTKTQVAIKIIDKT-RLDSSNLEKIYREVQLMKLLNHPN 85 Query: 400 IIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCH 567 II+ +V+ T L IV E+A GE+F+ + G E+EAR F Q++ V +CH Sbjct: 86 IIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARQKFWQILSAVEYCH 141
>MARK1_MOUSE (Q8VHJ5) Serine/threonine-protein kinase MARK1 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 1) (ELKL motif serine/threonine-protein kinase 3) Length = 795 Score = 86.7 bits (213), Expect = 4e-17 Identities = 52/140 (37%), Positives = 77/140 (55%), Gaps = 3/140 (2%) Frame = +1 Query: 157 ASREIATHRKTSNRSRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERG 336 +SR+ + S S E+ + Y + IG GNF KL R+ T VA+K I++ Sbjct: 35 SSRQNIPRCRNSITSATDEQPHIGNYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKT 94 Query: 337 YRID---ENVFREIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRF 507 + +FRE+ + L HPNI++ EV+ T L +VMEYA+GGE+F+ + GR Sbjct: 95 QLNPTSLQKLFREVRIMKILNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRM 154 Query: 508 HEDEARYFFQQLVCGVSFCH 567 E EAR F+Q+V V +CH Sbjct: 155 KEKEARAKFRQIVSAVQYCH 174
>MARK1_HUMAN (Q9P0L2) Serine/threonine-protein kinase MARK1 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 1) Length = 795 Score = 86.7 bits (213), Expect = 4e-17 Identities = 52/140 (37%), Positives = 77/140 (55%), Gaps = 3/140 (2%) Frame = +1 Query: 157 ASREIATHRKTSNRSRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERG 336 +SR+ + S S E+ + Y + IG GNF KL R+ T VA+K I++ Sbjct: 35 SSRQNIPRCRNSITSATDEQPHIGNYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKT 94 Query: 337 YRID---ENVFREIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRF 507 + +FRE+ + L HPNI++ EV+ T L +VMEYA+GGE+F+ + GR Sbjct: 95 QLNPTSLQKLFREVRIMKILNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRM 154 Query: 508 HEDEARYFFQQLVCGVSFCH 567 E EAR F+Q+V V +CH Sbjct: 155 KEKEARAKFRQIVSAVQYCH 174
>MARK1_RAT (O08678) Serine/threonine-protein kinase MARK1 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 1) Length = 793 Score = 86.7 bits (213), Expect = 4e-17 Identities = 52/140 (37%), Positives = 77/140 (55%), Gaps = 3/140 (2%) Frame = +1 Query: 157 ASREIATHRKTSNRSRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERG 336 +SR+ + S S E+ + Y + IG GNF KL R+ T VA+K I++ Sbjct: 35 SSRQNIPRCRNSITSATDEQPHIGNYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKT 94 Query: 337 YRID---ENVFREIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRF 507 + +FRE+ + L HPNI++ EV+ T L +VMEYA+GGE+F+ + GR Sbjct: 95 QLNPTSLQKLFREVRIMKILNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRM 154 Query: 508 HEDEARYFFQQLVCGVSFCH 567 E EAR F+Q+V V +CH Sbjct: 155 KEKEARAKFRQIVSAVQYCH 174
>SN1L1_RAT (Q9R1U5) Serine/threonine-protein kinase SNF1-like kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase SNF1LK) (Salt-inducible protein kinase) (Protein kinase KID2) Length = 776 Score = 86.3 bits (212), Expect = 6e-17 Identities = 47/116 (40%), Positives = 70/116 (60%), Gaps = 4/116 (3%) Frame = +1 Query: 232 YEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRID----ENVFREIVNHRSLRHPN 399 Y+ R +G GNF V KL R+R T+ VA+K I++ R+D E ++RE+ + L HPN Sbjct: 27 YDVERTLGKGNFAVVKLARHRVTKTQVAIKIIDKT-RLDSSNLEKIYREVQLMKLLNHPN 85 Query: 400 IIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCH 567 II+ +V+ T L IV E+A GE+F+ + G E+EAR F Q++ V +CH Sbjct: 86 IIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQILSAVEYCH 141
>MARK3_MOUSE (Q03141) MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1)| (MPK-10) (ELKL motif kinase 2) Length = 753 Score = 85.1 bits (209), Expect = 1e-16 Identities = 47/122 (38%), Positives = 71/122 (58%), Gaps = 3/122 (2%) Frame = +1 Query: 211 ERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRID---ENVFREIVNHR 381 E+ + Y ++ IG GNF KL R+ T VA+K I++ + +FRE+ + Sbjct: 49 EQPHIGNYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMK 108 Query: 382 SLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSF 561 L HPNI++ EV+ T L ++MEYA+GGE+F+ + GR E EAR F+Q+V V + Sbjct: 109 ILNHPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQY 168 Query: 562 CH 567 CH Sbjct: 169 CH 170
>MARK3_RAT (Q8VHF0) MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1)| Length = 797 Score = 85.1 bits (209), Expect = 1e-16 Identities = 47/122 (38%), Positives = 71/122 (58%), Gaps = 3/122 (2%) Frame = +1 Query: 211 ERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRID---ENVFREIVNHR 381 E+ + Y ++ IG GNF KL R+ T VA+K I++ + +FRE+ + Sbjct: 49 EQPHIGNYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMK 108 Query: 382 SLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSF 561 L HPNI++ EV+ T L ++MEYA+GGE+F+ + GR E EAR F+Q+V V + Sbjct: 109 ILNHPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQY 168 Query: 562 CH 567 CH Sbjct: 169 CH 170
>SN1L2_CHICK (Q9IA88) Serine/threonine-protein kinase SNF1-like kinase 2 (EC| 2.7.11.1) (Qin-induced kinase) Length = 798 Score = 84.7 bits (208), Expect = 2e-16 Identities = 46/117 (39%), Positives = 70/117 (59%), Gaps = 4/117 (3%) Frame = +1 Query: 232 YEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRID----ENVFREIVNHRSLRHPN 399 Y+ R +G GNF V KL R+R T+ VA+K I++ R+D E ++RE+ + L HP+ Sbjct: 26 YDIERTLGKGNFAVVKLARHRVTKTQVAIKIIDKT-RLDPSNLEKIYREVQIMKLLNHPH 84 Query: 400 IIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCHA 570 II+ +V+ T L IV E+A GE+F+ + G E EAR F Q++ V +CH+ Sbjct: 85 IIKLYQVMETKDMLYIVTEFAKNGEMFDHLTSNGHLSESEARKKFWQILSAVEYCHS 141
>SN1L2_MOUSE (Q8CFH6) Serine/threonine-protein kinase SNF1-like kinase 2 (EC| 2.7.11.1) (Salt-inducible kinase 2) Length = 931 Score = 84.3 bits (207), Expect = 2e-16 Identities = 45/116 (38%), Positives = 72/116 (62%), Gaps = 4/116 (3%) Frame = +1 Query: 232 YEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRID----ENVFREIVNHRSLRHPN 399 Y+ +G GNF V KL R+R T+ VA+K I++ ++D E ++RE+ + L HP+ Sbjct: 20 YDIEGTLGKGNFAVVKLGRHRTTKTEVAIKIIDKS-QLDAVNLEKIYREVQIMKMLDHPH 78 Query: 400 IIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCH 567 II+ +V+ T + L +V EYA GE+F+ + + GR +E EAR F Q++ V +CH Sbjct: 79 IIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCH 134
>SN1L1_HUMAN (P57059) Serine/threonine-protein kinase SNF1-like kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase SNF1LK) Length = 783 Score = 84.0 bits (206), Expect = 3e-16 Identities = 46/116 (39%), Positives = 70/116 (60%), Gaps = 4/116 (3%) Frame = +1 Query: 232 YEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRID----ENVFREIVNHRSLRHPN 399 Y+ R +G GNF V KL R+R T+ VA+K I++ R+D E ++RE+ + L HP+ Sbjct: 27 YDIERTLGKGNFAVVKLARHRVTKTQVAIKIIDKT-RLDSSNLEKIYREVQLMKLLNHPH 85 Query: 400 IIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCH 567 II+ +V+ T L IV E+A GE+F+ + G E+EAR F Q++ V +CH Sbjct: 86 IIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQILSAVEYCH 141
>AAPK2_CAEEL (Q95ZQ4) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMP-activated kinase 2) Length = 626 Score = 84.0 bits (206), Expect = 3e-16 Identities = 44/110 (40%), Positives = 65/110 (59%), Gaps = 4/110 (3%) Frame = +1 Query: 250 IGSGNFGVAKLMRNRDTRELVAMKFIER----GYRIDENVFREIVNHRSLRHPNIIRFKE 417 +G G FG K+ + T+ VA+K + R + + REI N RHP+IIR + Sbjct: 93 LGVGTFGKVKVGIHETTQYKVAVKILNRQKIKSLDVVGKIRREIQNLSLFRHPHIIRLYQ 152 Query: 418 VVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCH 567 V+ TP+ + ++ME+ +GGELF+ I GR EAR FFQQ++ GV +CH Sbjct: 153 VISTPSDIFMIMEHVSGGELFDYIVKHGRLKTAEARRFFQQIISGVDYCH 202
>SN1L2_PONPY (Q5REX1) Serine/threonine-protein kinase SNF1-like kinase 2 (EC| 2.7.11.1) Length = 925 Score = 83.6 bits (205), Expect = 4e-16 Identities = 45/116 (38%), Positives = 72/116 (62%), Gaps = 4/116 (3%) Frame = +1 Query: 232 YEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRID----ENVFREIVNHRSLRHPN 399 Y+ +G GNF V KL R+R T+ VA+K I++ ++D E ++RE+ + L HP+ Sbjct: 20 YDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKS-QLDAVNLEKIYREVQIMKMLDHPH 78 Query: 400 IIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCH 567 II+ +V+ T + L +V EYA GE+F+ + + GR +E EAR F Q++ V +CH Sbjct: 79 IIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCH 134
>CPK11_ARATH (O22932) CBL-interacting serine/threonine-protein kinase 11 (EC| 2.7.11.1) (SOS2-like protein kinase PKS5) (SOS-interacting protein 4) (SNF1-related kinase 3.22) Length = 435 Score = 83.6 bits (205), Expect = 4e-16 Identities = 46/119 (38%), Positives = 66/119 (55%), Gaps = 5/119 (4%) Frame = +1 Query: 229 KYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIER-----GYRIDENVFREIVNHRSLRH 393 KYE + +G G F R+R T + VA+K + + + N+ REI R L H Sbjct: 20 KYELGKLLGCGAFAKVFHARDRRTGQSVAVKILNKKKLLTNPALANNIKREISIMRRLSH 79 Query: 394 PNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCHA 570 PNI++ EV+ T + + ME+ GGELF +I GR ED +R +FQQL+ V +CHA Sbjct: 80 PNIVKLHEVMATKSKIFFAMEFVKGGELFNKISKHGRLSEDLSRRYFQQLISAVGYCHA 138
>SN1L2_HUMAN (Q9H0K1) Serine/threonine-protein kinase SNF1-like kinase 2 (EC| 2.7.11.1) (Qin-induced kinase) Length = 926 Score = 83.6 bits (205), Expect = 4e-16 Identities = 45/116 (38%), Positives = 72/116 (62%), Gaps = 4/116 (3%) Frame = +1 Query: 232 YEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRID----ENVFREIVNHRSLRHPN 399 Y+ +G GNF V KL R+R T+ VA+K I++ ++D E ++RE+ + L HP+ Sbjct: 20 YDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKS-QLDAVNLEKIYREVQIMKMLDHPH 78 Query: 400 IIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCH 567 II+ +V+ T + L +V EYA GE+F+ + + GR +E EAR F Q++ V +CH Sbjct: 79 IIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCH 134
>CPK15_ARATH (P92937) CBL-interacting serine/threonine-protein kinase 15 (EC| 2.7.11.1) (Serine/threonine-protein kinase ATPK10) (SOS2-like protein kinase PKS3) (SOS-interacting protein 2) (SNF1-related kinase 3.1) Length = 421 Score = 82.8 bits (203), Expect = 6e-16 Identities = 48/120 (40%), Positives = 68/120 (56%), Gaps = 4/120 (3%) Frame = +1 Query: 223 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERG----YRIDENVFREIVNHRSLR 390 M +YE + +G G F R+ T + VA+K I++ + E + REI R LR Sbjct: 9 MLRYEVGKFLGQGTFAKVYHARHLKTGDSVAIKVIDKERILKVGMTEQIKREISAMRLLR 68 Query: 391 HPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCHA 570 HPNI+ EV+ T + + VME+ GGELF ++ G+ ED AR +FQQLV V FCH+ Sbjct: 69 HPNIVELHEVMATKSKIYFVMEHVKGGELFNKV-STGKLREDVARKYFQQLVRAVDFCHS 127
>SNF1_CANTR (O94168) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 619 Score = 82.8 bits (203), Expect = 6e-16 Identities = 46/117 (39%), Positives = 71/117 (60%), Gaps = 4/117 (3%) Frame = +1 Query: 229 KYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDEN----VFREIVNHRSLRHP 396 +Y+ ++ +G G+FG KL ++ T + VA+K I R + V REI R LRHP Sbjct: 51 RYQIIKTLGEGSFGKVKLAQHVGTGQKVALKIINRKTLAKSDMQGRVEREISYLRLLRHP 110 Query: 397 NIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCH 567 +II+ +V+ + + +V+E+A G ELF+ I G+ EDEAR FFQQ++ V +CH Sbjct: 111 HIIKLYDVIKSKDEIIMVIEFA-GKELFDYIVQRGKMPEDEARRFFQQIIAAVEYCH 166
>SNF1_CANAL (P52497) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 620 Score = 82.4 bits (202), Expect = 8e-16 Identities = 46/117 (39%), Positives = 71/117 (60%), Gaps = 4/117 (3%) Frame = +1 Query: 229 KYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDEN----VFREIVNHRSLRHP 396 +Y+ ++ +G G+FG KL ++ T + VA+K I R + V REI R LRHP Sbjct: 52 RYQILKTLGEGSFGKVKLAQHLGTGQKVALKIINRKTLAKSDMQGRVEREISYLRLLRHP 111 Query: 397 NIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCH 567 +II+ +V+ + + +V+E+A G ELF+ I G+ EDEAR FFQQ++ V +CH Sbjct: 112 HIIKLYDVIKSKDEIIMVIEFA-GKELFDYIVQRGKMPEDEARRFFQQIIAAVEYCH 167
>SNF1_CANGA (Q00372) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 612 Score = 78.6 bits (192), Expect = 1e-14 Identities = 45/121 (37%), Positives = 69/121 (57%), Gaps = 4/121 (3%) Frame = +1 Query: 217 SGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDEN----VFREIVNHRS 384 S + Y+ V+ +G G+FG KL + T + VA+K I + + + REI R Sbjct: 34 SRVGNYQIVKTLGEGSFGKVKLAYHVTTGQKVALKIINKKVLAKSDMQGRIEREISYLRL 93 Query: 385 LRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFC 564 LRHP+II+ +V+ + + +V+EYA G ELF+ I + E EAR FFQQ++ V +C Sbjct: 94 LRHPHIIKLYDVIKSKDEIIMVIEYA-GNELFDYIVQRNKMSEQEARRFFQQIISAVEYC 152 Query: 565 H 567 H Sbjct: 153 H 153
>SNF1_YEAST (P06782) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 633 Score = 78.2 bits (191), Expect = 2e-14 Identities = 44/116 (37%), Positives = 67/116 (57%), Gaps = 4/116 (3%) Frame = +1 Query: 232 YEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDEN----VFREIVNHRSLRHPN 399 Y+ V+ +G G+FG KL + T + VA+K I + + + REI R LRHP+ Sbjct: 55 YQIVKTLGEGSFGKVKLAYHTTTGQKVALKIINKKVLAKSDMQGRIEREISYLRLLRHPH 114 Query: 400 IIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCH 567 II+ +V+ + + +V+EYA G ELF+ I + E EAR FFQQ++ V +CH Sbjct: 115 IIKLYDVIKSKDEIIMVIEYA-GNELFDYIVQRDKMSEQEARRFFQQIISAVEYCH 169
>NUAK1_HUMAN (O60285) NUAK family, SNF1-like kinase 1 (EC 2.7.11.1)| (AMPK-related protein kinase 5) Length = 661 Score = 76.3 bits (186), Expect = 6e-14 Identities = 44/117 (37%), Positives = 64/117 (54%), Gaps = 4/117 (3%) Frame = +1 Query: 229 KYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDE----NVFREIVNHRSLRHP 396 +YE +G G +G K R + +VA+K I + DE ++ REI SL HP Sbjct: 54 RYELQETLGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDEQDMVHIRREIEIMSSLNHP 113 Query: 397 NIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCH 567 +II EV + I+MEYA+ GEL++ I + R E E R+FF+Q+V V +CH Sbjct: 114 HIISIYEVFENKDKIVIIMEYASKGELYDYISERRRLSERETRHFFRQIVSAVHYCH 170
>NUAK1_MOUSE (Q641K5) NUAK family, SNF1-like kinase 1 (EC 2.7.11.1)| Length = 658 Score = 76.3 bits (186), Expect = 6e-14 Identities = 44/117 (37%), Positives = 64/117 (54%), Gaps = 4/117 (3%) Frame = +1 Query: 229 KYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDE----NVFREIVNHRSLRHP 396 +YE +G G +G K R + +VA+K I + DE ++ REI SL HP Sbjct: 55 RYELQETLGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDELDMVHIRREIEIMSSLNHP 114 Query: 397 NIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCH 567 +II EV + I+MEYA+ GEL++ I + R E E R+FF+Q+V V +CH Sbjct: 115 HIISIYEVFENKDKIVIIMEYASKGELYDYISERRRLSERETRHFFRQIVSAVHYCH 171
>MYLK_DICDI (P25323) Myosin light chain kinase (EC 2.7.11.18) (MLCK)| Length = 295 Score = 75.9 bits (185), Expect = 8e-14 Identities = 41/117 (35%), Positives = 65/117 (55%), Gaps = 3/117 (2%) Frame = +1 Query: 232 YEPVREIGSGNFGVAKLMRNRDTRELVAMKFI---ERGYRIDENVFREIVNHRSLRHPNI 402 YE E+G G F + L N+ T++ A+K I E G ++N+ E+ + + HPNI Sbjct: 8 YEFKEELGRGAFSIVYLGENKQTKQRYAIKVINKSELGKDYEKNLKMEVDILKKVNHPNI 67 Query: 403 IRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCHAM 573 I KE+ TP L +VME GGELF++I + G + E +A +++V V + H + Sbjct: 68 IALKELFDTPEKLYLVMELVTGGELFDKIVEKGSYSEADAANLVKKIVSAVGYLHGL 124
>CHK1_XENLA (Q6DE87) Serine/threonine-protein kinase Chk1 (EC 2.7.11.1) (xChk1| protein) Length = 474 Score = 75.5 bits (184), Expect = 1e-13 Identities = 43/119 (36%), Positives = 67/119 (56%), Gaps = 2/119 (1%) Frame = +1 Query: 223 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRID--ENVFREIVNHRSLRHP 396 ++ ++ V+ +G G +G +L NR T E VA+K ++ D EN+ +EI +R L H Sbjct: 6 VEDWDLVQTLGEGAYGEVQLAVNRKTEEAVAVKIVDMTRAADCPENIKKEICINRMLSHT 65 Query: 397 NIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCHAM 573 NI+RF + +EY GGELF+RI E +A+ FFQQL+ GV + H++ Sbjct: 66 NIVRFYGHRREGNIQYLFLEYCRGGELFDRIEPDVGMPEQDAQKFFQQLIAGVEYLHSI 124
>RKIN1_SECCE (Q02723) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 502 Score = 75.5 bits (184), Expect = 1e-13 Identities = 43/113 (38%), Positives = 62/113 (54%), Gaps = 7/113 (6%) Frame = +1 Query: 250 IGSGNFGVAKLMRNRDTRELVAMKFIERGY----RIDENVFREIVNHR---SLRHPNIIR 408 +G G F + ++ TR VA+K + R ++E REI R L HP+IIR Sbjct: 20 LGVGTFAKVIIAEHKHTRHKVAIKVLNRRQMRAPEMEEKAKREIKILRLFIDLIHPHIIR 79 Query: 409 FKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCH 567 EV++TP + +VMEY G+L + I + R EDEAR FQQ++ V +CH Sbjct: 80 VYEVIVTPKDIFVVMEYCQNGDLLDYILEKRRLQEDEARRTFQQIISAVEYCH 132
>CHK1_CHICK (Q8AYC9) Serine/threonine-protein kinase Chk1 (EC 2.7.11.1)| Length = 476 Score = 75.1 bits (183), Expect = 1e-13 Identities = 42/119 (35%), Positives = 68/119 (57%), Gaps = 2/119 (1%) Frame = +1 Query: 223 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRID--ENVFREIVNHRSLRHP 396 ++ ++ V+ +G G +G +L NR T E VA+K ++ D EN+ +EI ++ L H Sbjct: 6 VEDWDLVQTLGEGAYGEVQLAVNRRTEEAVAVKIVDMKRAADCPENIKKEICINKMLNHE 65 Query: 397 NIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCHAM 573 N+++F + +EY +GGELF+RI E EA+ FFQQL+ GV + H+M Sbjct: 66 NVVKFYGHRREGATQYLFLEYCSGGELFDRIEPDIGMPEPEAQRFFQQLIAGVVYLHSM 124
>DAPK1_MOUSE (Q80YE7) Death-associated protein kinase 1 (EC 2.7.11.1) (DAP| kinase 1) Length = 1442 Score = 75.1 bits (183), Expect = 1e-13 Identities = 42/129 (32%), Positives = 69/129 (53%), Gaps = 7/129 (5%) Frame = +1 Query: 208 RERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRID-------ENVFRE 366 R+ + D Y+ E+GSG F V K R + T A KFI++ E++ RE Sbjct: 5 RQENVDDYYDTGEELGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRGVSREDIERE 64 Query: 367 IVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLV 546 + + +RHPN+I EV T + +++E AGGELF+ + + E+EA F +Q++ Sbjct: 65 VSILKEIRHPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQIL 124 Query: 547 CGVSFCHAM 573 GV + H++ Sbjct: 125 SGVYYLHSL 133
>DAPK3_HUMAN (O43293) Death-associated protein kinase 3 (EC 2.7.11.1) (DAP| kinase 3) (DAP-like kinase) (Dlk) (ZIP-kinase) Length = 454 Score = 75.1 bits (183), Expect = 1e-13 Identities = 43/129 (33%), Positives = 69/129 (53%), Gaps = 8/129 (6%) Frame = +1 Query: 208 RERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIE--------RGYRIDENVFR 363 R+ D YE E+GSG F + + R + T + A KFI+ RG +E + R Sbjct: 5 RQEDVEDHYEMGEELGSGQFAIVRKCRQKGTGKEYAAKFIKKRRLSSSRRGVSREE-IER 63 Query: 364 EIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQL 543 E+ R +RHPNII ++ T + +++E +GGELF+ + + EDEA F +Q+ Sbjct: 64 EVNILREIRHPNIITLHDIFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQI 123 Query: 544 VCGVSFCHA 570 + GV + H+ Sbjct: 124 LDGVHYLHS 132
>SSP1_SCHPO (P50526) Serine/threonine-protein kinase ssp1 (EC 2.7.11.1)| Length = 652 Score = 74.7 bits (182), Expect = 2e-13 Identities = 50/148 (33%), Positives = 77/148 (52%), Gaps = 14/148 (9%) Frame = +1 Query: 166 EIATHRKTSNR-SRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYR 342 E+ +K R R R ++ YE ++E+G G G KL R+ TREL+A+K I + R Sbjct: 112 EVKETKKIRKRFDRFSGRKYINHYEIIKELGRGMHGKVKLGRDTVTRELLAIKIIPKTER 171 Query: 343 ID-----------ENVFREIVNHRSLRHPNIIRFKEVVLTP--THLGIVMEYAAGGELFE 483 E V REI + HPN++R +EV+ P T + +V+EY +GGE+ Sbjct: 172 RPKLGRANASSQKEKVRREIAILKKCVHPNVVRLREVIDDPSSTKVYLVLEYMSGGEVPW 231 Query: 484 RICDAGRFHEDEARYFFQQLVCGVSFCH 567 CD+ EAR +F+ +V G+ + H Sbjct: 232 TDCDSPVLSISEARQYFRDVVLGLEYLH 259
>GIN4_YEAST (Q12263) Serine/threonine-protein kinase GIN4 (EC 2.7.11.1)| Length = 1142 Score = 74.3 bits (181), Expect = 2e-13 Identities = 45/126 (35%), Positives = 65/126 (51%), Gaps = 18/126 (14%) Frame = +1 Query: 250 IGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVF------------------REIVN 375 +G G+ G +L RN T + A+K I + NV REI+ Sbjct: 25 LGLGSTGKVQLARNGSTGQEAAVKVISKAVFNTGNVSGTSIVGSTTPDALPYGIEREIII 84 Query: 376 HRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGV 555 + L HPN++R +V T T L +V+EYA GELF + + G E EA FF+Q++ GV Sbjct: 85 MKLLNHPNVLRLYDVWETNTDLYLVLEYAEKGELFNLLVERGPLPEHEAIRFFRQIIIGV 144 Query: 556 SFCHAM 573 S+CHA+ Sbjct: 145 SYCHAL 150
>MARK3_HUMAN (P27448) MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1)| (Cdc25C-associated protein kinase 1) (cTAK1) (C-TAK1) (Serine/threonine protein kinase p78) (Ser/Thr protein kinase PAR-1) (Protein kinase STK10) Length = 776 Score = 73.9 bits (180), Expect = 3e-13 Identities = 43/113 (38%), Positives = 65/113 (57%), Gaps = 3/113 (2%) Frame = +1 Query: 211 ERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRID---ENVFREIVNHR 381 E+ + Y ++ IG GNF KL R+ T VA+K I++ + +FRE+ + Sbjct: 49 EQPHIGNYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMK 108 Query: 382 SLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQ 540 L HPNI++ EV+ T L ++MEYA+GGE+F+ + GR E EAR F+Q Sbjct: 109 ILNHPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQ 161
>KPSH1_BRARE (Q501V0) Serine/threonine-protein kinase H1 homolog (EC 2.7.11.1)| Length = 422 Score = 73.9 bits (180), Expect = 3e-13 Identities = 49/135 (36%), Positives = 70/135 (51%), Gaps = 2/135 (1%) Frame = +1 Query: 175 THRKTSNRSRER-ERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDE 351 +HRK + R + + KY+ IG G+F + +R TR+ A+K IE YR Sbjct: 76 SHRKKVAKYRAKFDPRVTAKYDIKALIGRGSFSRVVRVEHRSTRQPYAIKMIETRYREGR 135 Query: 352 NVFR-EIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARY 528 V E+ R +RH NII+ EV T + +VME A GGELF+RI G F E +A Sbjct: 136 EVCESELCVLRRVRHTNIIQLMEVFETAERVYMVMELATGGELFDRIITRGSFTERDATR 195 Query: 529 FFQQLVCGVSFCHAM 573 Q ++ GV + H + Sbjct: 196 VLQMVLDGVKYLHTL 210
>KCC1B_RAT (O70150) Calcium/calmodulin-dependent protein kinase type 1B (EC| 2.7.11.17) (CaM kinase IB) (CaM kinase I beta) (CaMKI-beta) (CaM-KI beta) (Pregnancy up-regulated non-ubiquitously expressed CaM kinase homolog) Length = 343 Score = 73.6 bits (179), Expect = 4e-13 Identities = 43/116 (37%), Positives = 67/116 (57%), Gaps = 2/116 (1%) Frame = +1 Query: 232 YEPVREIGSGNFGVAKLMRNRDTRELVAMKFI-ERGYRIDEN-VFREIVNHRSLRHPNII 405 YE ++GSG F L + R + LVA+K I ++ R E V EI R + HPNI+ Sbjct: 15 YEIREKLGSGAFSEVMLAQERGSAHLVALKCIPKKALRGKEALVENEIAVLRRISHPNIV 74 Query: 406 RFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCHAM 573 ++V +P+HL + ME GGELF+RI + G + E +A + Q++ VS+ H++ Sbjct: 75 ALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAVSYLHSL 130
>KCC1B_MOUSE (Q9QYK9) Calcium/calmodulin-dependent protein kinase type 1B (EC| 2.7.11.17) (CaM kinase IB) (CaM kinase I beta) (CaMKI-beta) (CaM-KI beta) (Pregnancy up-regulated non-ubiquitously expressed CaM kinase homolog) Length = 343 Score = 73.6 bits (179), Expect = 4e-13 Identities = 43/116 (37%), Positives = 67/116 (57%), Gaps = 2/116 (1%) Frame = +1 Query: 232 YEPVREIGSGNFGVAKLMRNRDTRELVAMKFI-ERGYRIDEN-VFREIVNHRSLRHPNII 405 YE ++GSG F L + R + LVA+K I ++ R E V EI R + HPNI+ Sbjct: 15 YEIREKLGSGAFSEVMLAQERGSAHLVALKCIPKKALRGKEALVENEIAVLRRISHPNIV 74 Query: 406 RFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCHAM 573 ++V +P+HL + ME GGELF+RI + G + E +A + Q++ VS+ H++ Sbjct: 75 ALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAVSYLHSL 130
>DAPK3_RAT (O88764) Death-associated protein kinase 3 (EC 2.7.11.1) (DAP| kinase 3) (DAP-like kinase) (Dlk) (ZIP-kinase) Length = 448 Score = 73.2 bits (178), Expect = 5e-13 Identities = 43/129 (33%), Positives = 68/129 (52%), Gaps = 8/129 (6%) Frame = +1 Query: 208 RERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIE--------RGYRIDENVFR 363 R+ D YE E+GSG F + + + + T A KFI+ RG +E + R Sbjct: 5 RQEDVEDHYEMGEELGSGQFAIVRKCQQKGTGMEYAAKFIKKRRLPSSRRGVSREE-IER 63 Query: 364 EIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQL 543 E+ R +RHPNII +V T + +++E +GGELF+ + + EDEA F +Q+ Sbjct: 64 EVSILREIRHPNIITLHDVFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQI 123 Query: 544 VCGVSFCHA 570 + GV + H+ Sbjct: 124 LDGVHYLHS 132
>DAPK3_MOUSE (O54784) Death-associated protein kinase 3 (EC 2.7.11.1) (DAP| kinase 3) (DAP-like kinase) (Dlk) (ZIP-kinase) Length = 448 Score = 73.2 bits (178), Expect = 5e-13 Identities = 43/129 (33%), Positives = 68/129 (52%), Gaps = 8/129 (6%) Frame = +1 Query: 208 RERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIE--------RGYRIDENVFR 363 R+ D YE E+GSG F + + + + T A KFI+ RG +E + R Sbjct: 5 RQEDVEDHYEMGEELGSGQFAIVRKCQQKGTGMEYAAKFIKKRRLPSSRRGVSREE-IER 63 Query: 364 EIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQL 543 E+ R +RHPNII +V T + +++E +GGELF+ + + EDEA F +Q+ Sbjct: 64 EVSILREIRHPNIITLHDVFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQI 123 Query: 544 VCGVSFCHA 570 + GV + H+ Sbjct: 124 LDGVHYLHS 132
>AAPK1_CAEEL (P45894) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMP-activated kinase 1) Length = 589 Score = 72.8 bits (177), Expect = 7e-13 Identities = 43/110 (39%), Positives = 58/110 (52%), Gaps = 4/110 (3%) Frame = +1 Query: 250 IGSGNFGVAKLMRNRDTRELVAMKFIERGYRID----ENVFREIVNHRSLRHPNIIRFKE 417 IG G FG K + T VA+K + RG EI N + L HP+I R Sbjct: 30 IGKGAFGAVKRGTHIQTGYDVAIKILNRGRMKGLGTVNKTRNEIDNLQKLTHPHITRLFR 89 Query: 418 VVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCH 567 V+ TP+ + +VME +GGELF I G E+R +FQQ++ GVS+CH Sbjct: 90 VISTPSDIFLVMELVSGGELFSYITRKGALPIRESRRYFQQIISGVSYCH 139
>BRSK1_HUMAN (Q8TDC3) BR serine/threonine-protein kinase 1 (EC 2.7.11.1) (SAD1| kinase) (SAD1A) Length = 794 Score = 72.8 bits (177), Expect = 7e-13 Identities = 41/127 (32%), Positives = 70/127 (55%), Gaps = 4/127 (3%) Frame = +1 Query: 202 RERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVF----REI 369 R R + Y + +G G G+ KL + T + VA+K + R ++ E+V REI Sbjct: 40 RGRHAQYVGPYRLEKTLGKGQTGLVKLGVHCITGQKVAIKIVNRE-KLSESVLMKVEREI 98 Query: 370 VNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVC 549 + + HP++++ +V +L +V+E+ +GGELF+ + GR EAR FF+Q+V Sbjct: 99 AILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVS 158 Query: 550 GVSFCHA 570 + FCH+ Sbjct: 159 ALDFCHS 165
>DAPK1_HUMAN (P53355) Death-associated protein kinase 1 (EC 2.7.11.1) (DAP| kinase 1) Length = 1432 Score = 72.8 bits (177), Expect = 7e-13 Identities = 41/129 (31%), Positives = 69/129 (53%), Gaps = 7/129 (5%) Frame = +1 Query: 208 RERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRID-------ENVFRE 366 R+ + D Y+ E+GSG F V K R + T A KFI++ E++ RE Sbjct: 5 RQENVDDYYDTGEELGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRGVSREDIERE 64 Query: 367 IVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLV 546 + + ++HPN+I EV T + +++E AGGELF+ + + E+EA F +Q++ Sbjct: 65 VSILKEIQHPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQIL 124 Query: 547 CGVSFCHAM 573 GV + H++ Sbjct: 125 NGVYYLHSL 133
>KCC1B_HUMAN (Q6P2M8) Calcium/calmodulin-dependent protein kinase type 1B (EC| 2.7.11.17) (CaM kinase IB) (CaM kinase I beta) (CaMKI-beta) (CaM-KI beta) (Pregnancy up-regulated non-ubiquitously expressed CaM kinase) Length = 343 Score = 72.8 bits (177), Expect = 7e-13 Identities = 43/116 (37%), Positives = 66/116 (56%), Gaps = 2/116 (1%) Frame = +1 Query: 232 YEPVREIGSGNFGVAKLMRNRDTRELVAMKFI-ERGYRIDEN-VFREIVNHRSLRHPNII 405 YE +GSG F L + R + LVA+K I ++ R E V EI R + HPNI+ Sbjct: 15 YEIRERLGSGAFSEVVLAQERGSAHLVALKCIPKKALRGKEALVENEIAVLRRISHPNIV 74 Query: 406 RFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCHAM 573 ++V +P+HL + ME GGELF+RI + G + E +A + Q++ VS+ H++ Sbjct: 75 ALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAVSYLHSL 130
>KPSH1_MOUSE (Q91YA2) Serine/threonine-protein kinase H1 (EC 2.7.11.1) (PSK-H1)| Length = 423 Score = 72.4 bits (176), Expect = 9e-13 Identities = 46/116 (39%), Positives = 63/116 (54%), Gaps = 1/116 (0%) Frame = +1 Query: 229 KYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFR-EIVNHRSLRHPNII 405 KY+ IG G+F + +R TR+ A+K IE YR V E+ R +RH NII Sbjct: 96 KYDIKALIGRGSFSRVVRVEHRATRQPYAIKMIETKYREGREVCESELRVLRRVRHANII 155 Query: 406 RFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCHAM 573 + EV T + +VME A GGELF+RI G F E +A Q ++ GV + HA+ Sbjct: 156 QLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMVLDGVRYLHAL 211
>KPSH1_HUMAN (P11801) Serine/threonine-protein kinase H1 (EC 2.7.11.1) (PSK-H1)| Length = 423 Score = 72.4 bits (176), Expect = 9e-13 Identities = 46/116 (39%), Positives = 63/116 (54%), Gaps = 1/116 (0%) Frame = +1 Query: 229 KYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFR-EIVNHRSLRHPNII 405 KY+ IG G+F + +R TR+ A+K IE YR V E+ R +RH NII Sbjct: 96 KYDIKALIGRGSFSRVVRVEHRATRQPYAIKMIETKYREGREVCESELRVLRRVRHANII 155 Query: 406 RFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCHAM 573 + EV T + +VME A GGELF+RI G F E +A Q ++ GV + HA+ Sbjct: 156 QLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMVLDGVRYLHAL 211
>SNRK_MOUSE (Q8VDU5) SNF-related serine/threonine-protein kinase (EC 2.7.11.1)| (SNF1-related kinase) Length = 748 Score = 72.4 bits (176), Expect = 9e-13 Identities = 41/119 (34%), Positives = 73/119 (61%), Gaps = 5/119 (4%) Frame = +1 Query: 232 YEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDE----NVFREIVNHRSLRHPN 399 Y+ + +G G+F V KL R+ T E VA+K I++ ++D ++F+E+ + ++HPN Sbjct: 16 YDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKT-KLDTLATGHLFQEVRCMKLVQHPN 74 Query: 400 IIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGR-FHEDEARYFFQQLVCGVSFCHAM 573 I+R EV+ T T L +++E GG++F+ I +ED A+ +F Q+V +S+CH + Sbjct: 75 IVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAISYCHKL 133
>NEK3_HUMAN (P51956) Serine/threonine-protein kinase Nek3 (EC 2.7.11.1)| (NimA-related protein kinase 3) (HSPK 36) Length = 506 Score = 72.4 bits (176), Expect = 9e-13 Identities = 44/119 (36%), Positives = 65/119 (54%), Gaps = 4/119 (3%) Frame = +1 Query: 223 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIE--RGYRIDENVFREIVNHRSLRHP 396 MD Y +R IG G+FG A L+++ + ++ AMK I + + +N +E V ++HP Sbjct: 1 MDDYMVLRMIGEGSFGRALLVQHESSNQMFAMKEIRLPKSFSNTQNSRKEAVLLAKMKHP 60 Query: 397 NIIRFKEVVLTPTHLGIVMEYAAGGELFERICD--AGRFHEDEARYFFQQLVCGVSFCH 567 NI+ FKE HL IVMEY GG+L ++I F ED +F Q+ GV+ H Sbjct: 61 NIVAFKESFEAEGHLYIVMEYCDGGDLMQKIKQQKGKLFPEDMILNWFTQMCLGVNHIH 119
>SNRK_HUMAN (Q9NRH2) SNF-related serine/threonine-protein kinase (EC 2.7.11.1)| (SNF1-related kinase) Length = 765 Score = 72.4 bits (176), Expect = 9e-13 Identities = 41/119 (34%), Positives = 73/119 (61%), Gaps = 5/119 (4%) Frame = +1 Query: 232 YEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDE----NVFREIVNHRSLRHPN 399 Y+ + +G G+F V KL R+ T E VA+K I++ ++D ++F+E+ + ++HPN Sbjct: 16 YDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKT-KLDTLATGHLFQEVRCMKLVQHPN 74 Query: 400 IIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGR-FHEDEARYFFQQLVCGVSFCHAM 573 I+R EV+ T T L +++E GG++F+ I +ED A+ +F Q+V +S+CH + Sbjct: 75 IVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAISYCHKL 133
>SNRK_RAT (Q63553) SNF-related serine/threonine-protein kinase (EC 2.7.11.1)| (SNF1-related kinase) Length = 746 Score = 72.4 bits (176), Expect = 9e-13 Identities = 41/119 (34%), Positives = 73/119 (61%), Gaps = 5/119 (4%) Frame = +1 Query: 232 YEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDE----NVFREIVNHRSLRHPN 399 Y+ + +G G+F V KL R+ T E VA+K I++ ++D ++F+E+ + ++HPN Sbjct: 16 YDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKT-KLDTLATGHLFQEVRCMKLVQHPN 74 Query: 400 IIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGR-FHEDEARYFFQQLVCGVSFCHAM 573 I+R EV+ T T L +++E GG++F+ I +ED A+ +F Q+V +S+CH + Sbjct: 75 IVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAISYCHKL 133
>SCH9_YEAST (P11792) Serine/threonine-protein kinase SCH9 (EC 2.7.11.1)| Length = 823 Score = 71.2 bits (173), Expect = 2e-12 Identities = 38/135 (28%), Positives = 67/135 (49%), Gaps = 7/135 (5%) Frame = +1 Query: 184 KTSNRSRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFR 363 K + + ++ G +E +R +G G FG ++ +DT+ + AMK + + + +N Sbjct: 395 KWTYKQTKKRHYGPQDFEVLRLLGKGTFGQVYQVKKKDTQRIYAMKVLSKKVIVKKNEIA 454 Query: 364 EIVNHRSL-------RHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEA 522 + R++ P I+ K TPT L +V +Y +GGELF + GRF ED A Sbjct: 455 HTIGERNILVTTASKSSPFIVGLKFSFQTPTDLYLVTDYMSGGELFWHLQKEGRFSEDRA 514 Query: 523 RYFFQQLVCGVSFCH 567 +++ +LV + H Sbjct: 515 KFYIAELVLALEHLH 529
>KCC4_MOUSE (P08414) Calcium/calmodulin-dependent protein kinase type IV (EC| 2.7.11.17) (CAM kinase-GR) (CaMK IV) Length = 469 Score = 71.2 bits (173), Expect = 2e-12 Identities = 39/115 (33%), Positives = 67/115 (58%), Gaps = 1/115 (0%) Frame = +1 Query: 226 DKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFR-EIVNHRSLRHPNI 402 D +E E+G G + + + T++ A+K +++ +D+ + R EI L HPNI Sbjct: 40 DFFEVESELGRGATSIVYRCKQKGTQKPYALKVLKK--TVDKKIVRTEIGVLLRLSHPNI 97 Query: 403 IRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCH 567 I+ KE+ TPT + +V+E GGELF+RI + G + E +AR +Q++ V++ H Sbjct: 98 IKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDARDAVKQILEAVAYLH 152
>CHK1_RAT (Q91ZN7) Serine/threonine-protein kinase Chk1 (EC 2.7.11.1)| Length = 476 Score = 70.9 bits (172), Expect = 2e-12 Identities = 40/119 (33%), Positives = 67/119 (56%), Gaps = 2/119 (1%) Frame = +1 Query: 223 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRID--ENVFREIVNHRSLRHP 396 ++ ++ V+ +G G +G +L NR T E VA+K ++ ID EN+ +EI ++ L H Sbjct: 6 VEDWDLVQTLGEGAYGEVQLAVNRITEEAVAVKIVDMKRAIDCPENIKKEICINKMLNHE 65 Query: 397 NIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCHAM 573 N+++F + +EY +GGELF+RI E +A+ FF QL+ GV + H + Sbjct: 66 NVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEQDAQRFFHQLMAGVVYLHGI 124
>BRSK2_HUMAN (Q8IWQ3) BR serine/threonine-protein kinase 2 (EC 2.7.11.1)| (Serine/threonine-protein kinase 29) (SAD1B) Length = 736 Score = 70.9 bits (172), Expect = 2e-12 Identities = 38/117 (32%), Positives = 67/117 (57%), Gaps = 4/117 (3%) Frame = +1 Query: 232 YEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVF----REIVNHRSLRHPN 399 Y + +G G G+ KL + T + VA+K + R ++ E+V REI + + HP+ Sbjct: 19 YRLEKTLGKGQTGLVKLGVHCVTCQKVAIKIVNRE-KLSESVLMKVEREIAILKLIEHPH 77 Query: 400 IIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCHA 570 +++ +V +L +V+E+ +GGELF+ + GR EAR FF+Q++ + FCH+ Sbjct: 78 VLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHS 134
>CHK1_HUMAN (O14757) Serine/threonine-protein kinase Chk1 (EC 2.7.11.1)| Length = 476 Score = 70.1 bits (170), Expect = 4e-12 Identities = 39/119 (32%), Positives = 67/119 (56%), Gaps = 2/119 (1%) Frame = +1 Query: 223 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRID--ENVFREIVNHRSLRHP 396 ++ ++ V+ +G G +G +L NR T E VA+K ++ +D EN+ +EI ++ L H Sbjct: 6 VEDWDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCPENIKKEICINKMLNHE 65 Query: 397 NIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCHAM 573 N+++F + +EY +GGELF+RI E +A+ FF QL+ GV + H + Sbjct: 66 NVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGI 124
>YP141_YEAST (Q03002) Putative serine/threonine-protein kinase YPL141C (EC| 2.7.11.1) Length = 865 Score = 70.1 bits (170), Expect = 4e-12 Identities = 43/122 (35%), Positives = 64/122 (52%), Gaps = 15/122 (12%) Frame = +1 Query: 250 IGSGNFGVAKLMRNR----------DTRELVAMKFIERG-----YRIDENVFREIVNHRS 384 +G G FG KL + D + VA+K I+R YR + ++REI + Sbjct: 47 LGEGEFGKVKLGWPKNFSNSSNSTFDFPKQVAIKLIKRDSISNDYRKEVKIYREINALKH 106 Query: 385 LRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFC 564 L HPNI++ +EV+ ++GIV+EYA GGE ++ I R E A F QL+ GV + Sbjct: 107 LSHPNIVKLEEVLQNSRYIGIVLEYACGGEFYKYIQKKRRLKEMNACRLFSQLISGVHYI 166 Query: 565 HA 570 H+ Sbjct: 167 HS 168
>CHK1_MOUSE (O35280) Serine/threonine-protein kinase Chk1 (EC 2.7.11.1)| Length = 476 Score = 69.7 bits (169), Expect = 6e-12 Identities = 40/119 (33%), Positives = 67/119 (56%), Gaps = 2/119 (1%) Frame = +1 Query: 223 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRID--ENVFREIVNHRSLRHP 396 ++ ++ V+ +G G +G +L NR T E VA+K ++ ID EN+ +EI ++ L H Sbjct: 6 VEDWDLVQTLGEGAYGEVQLAVNRITEEAVAVKIVDMKRAIDCPENIKKEICINKMLSHE 65 Query: 397 NIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCHAM 573 N+++F + +EY +GGELF+RI E +A+ FF QL+ GV + H + Sbjct: 66 NVVKFYGHRREGHIQYLFLEYCSGGELFDRIEPDIGMPEQDAQRFFHQLMAGVVYLHGI 124
>CDC2H_DICDI (P34117) CDC2-like serine/threonine-protein kinase CRP (EC| 2.7.11.22) (EC 2.7.11.23) Length = 292 Score = 69.7 bits (169), Expect = 6e-12 Identities = 42/121 (34%), Positives = 65/121 (53%), Gaps = 6/121 (4%) Frame = +1 Query: 223 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENV----FREIVNHRSLR 390 M+KY + ++G G +G+ +NR+T E+VA+K I DE V REI + L+ Sbjct: 1 MEKYSKIEKLGEGTYGIVNKAKNRETGEIVALKRIRLDSE-DEGVPCTAIREISLLKELK 59 Query: 391 HPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICD--AGRFHEDEARYFFQQLVCGVSFC 564 HPNI+R +V+ T L +V EY + ++ D G + + F QL+ GV+FC Sbjct: 60 HPNIVRLHDVIHTERKLTLVFEYL--DQDLKKYLDECGGEISKPTIKSFMYQLLKGVAFC 117 Query: 565 H 567 H Sbjct: 118 H 118
>KCC4_YEAST (P25389) Probable serine/threonine-protein kinase KCC4 (EC| 2.7.11.1) Length = 1037 Score = 69.3 bits (168), Expect = 7e-12 Identities = 43/145 (29%), Positives = 71/145 (48%), Gaps = 12/145 (8%) Frame = +1 Query: 175 THRKTSNRSRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYR---- 342 T T S + S + ++ +G G+ G +L ++ T A+K I + Sbjct: 2 TVANTETHSAAKPSSTIGPWKLGETLGFGSTGKVQLAQHERTGHRTAVKVISKSIFNNNG 61 Query: 343 --------IDENVFREIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDA 498 + N+ REIV + L HPN++ +V T +L +++EYA GELF + D Sbjct: 62 NHSNDDSVLPYNIEREIVIMKLLSHPNVLSLYDVWETNNNLYLILEYAEKGELFNLLVDH 121 Query: 499 GRFHEDEARYFFQQLVCGVSFCHAM 573 G E EA F+Q++ G+S+CHA+ Sbjct: 122 GPLPEREAINCFRQIIIGISYCHAL 146
>KCC4_HUMAN (Q16566) Calcium/calmodulin-dependent protein kinase type IV (EC| 2.7.11.17) (CAM kinase-GR) (CaMK IV) Length = 473 Score = 68.9 bits (167), Expect = 9e-12 Identities = 38/115 (33%), Positives = 66/115 (57%), Gaps = 1/115 (0%) Frame = +1 Query: 226 DKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFR-EIVNHRSLRHPNI 402 D +E E+G G + + + T++ A+K +++ +D+ + R EI L HPNI Sbjct: 44 DFFEVESELGRGATSIVYRCKQKGTQKPYALKVLKK--TVDKKIVRTEIGVLLRLSHPNI 101 Query: 403 IRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCH 567 I+ KE+ TPT + +V+E GGELF+RI + G + E +A +Q++ V++ H Sbjct: 102 IKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAVAYLH 156
>KCC4_RAT (P13234) Calcium/calmodulin-dependent protein kinase type IV (EC| 2.7.11.17) (CAM kinase-GR) (CaMK IV) (Calspermin) Length = 474 Score = 68.9 bits (167), Expect = 9e-12 Identities = 38/115 (33%), Positives = 66/115 (57%), Gaps = 1/115 (0%) Frame = +1 Query: 226 DKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFR-EIVNHRSLRHPNI 402 D +E E+G G + + + T++ A+K +++ +D+ + R EI L HPNI Sbjct: 40 DFFEVESELGRGATSIVYRCKQKGTQKPYALKVLKK--TVDKKIVRTEIGVLLRLSHPNI 97 Query: 403 IRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCH 567 I+ KE+ TPT + +V+E GGELF+RI + G + E +A +Q++ V++ H Sbjct: 98 IKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAVAYLH 152
>DAPK2_MOUSE (Q8VDF3) Death-associated protein kinase 2 (EC 2.7.11.1) (DAP| kinase 2) (DAP-kinase-related protein 1) (DRP-1) Length = 370 Score = 68.6 bits (166), Expect = 1e-11 Identities = 40/135 (29%), Positives = 68/135 (50%), Gaps = 7/135 (5%) Frame = +1 Query: 184 KTSNRSRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYR------- 342 ++ N +++ D Y+ E+GSG F + K R + T A KFI++ Sbjct: 7 RSPNMETFKQQKVEDFYDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGV 66 Query: 343 IDENVFREIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEA 522 E + RE+ R + HPNII +V T + +++E +GGELF+ + E+EA Sbjct: 67 CREEIEREVSILRQVLHPNIITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEA 126 Query: 523 RYFFQQLVCGVSFCH 567 F +Q++ GV++ H Sbjct: 127 TSFIKQILDGVNYLH 141
>STK36_HUMAN (Q9NRP7) Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused| homolog) Length = 1315 Score = 68.6 bits (166), Expect = 1e-11 Identities = 42/119 (35%), Positives = 67/119 (56%), Gaps = 3/119 (2%) Frame = +1 Query: 223 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDE---NVFREIVNHRSLRH 393 M+KY + IG G+FG R + + ++VA+KFI + R ++ N+ REI R LRH Sbjct: 1 MEKYHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLRH 60 Query: 394 PNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCHA 570 PNI+ + T + +V +YA GELF+ + D G+ ED+ + QLV + + H+ Sbjct: 61 PNIVHMLDSFETDKEVVVVTDYAE-GELFQILEDDGKLPEDQVQAIAAQLVSALYYLHS 118
>KS6A4_MOUSE (Q9Z2B9) Ribosomal protein S6 kinase alpha-4 (EC 2.7.11.1) (Nuclear| mitogen-and stress-activated protein kinase 2) (90 kDa ribosomal protein S6 kinase 4) (RSK-like protein kinase) (RLSK) Length = 773 Score = 68.2 bits (165), Expect = 2e-11 Identities = 42/116 (36%), Positives = 60/116 (51%), Gaps = 1/116 (0%) Frame = +1 Query: 223 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHRSLR-HPN 399 +D EP +G G+F V + R R + + A+K + R R++EN RE+ R + HPN Sbjct: 410 LDLREPA--LGQGSFSVCRRCRQRQSGQEFAVKILSR--RLEENTQREVAALRLCQSHPN 465 Query: 400 IIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCH 567 ++ EV+ H +V+E GGEL E I F E EA + LV VSF H Sbjct: 466 VVNLHEVLHDQLHTYLVLELLRGGELLEHIRKKRLFSESEASQILRSLVSAVSFMH 521 Score = 43.1 bits (100), Expect = 6e-04 Identities = 29/137 (21%), Positives = 62/137 (45%), Gaps = 9/137 (6%) Frame = +1 Query: 190 SNRSRERERSGMDKYEPVREIGSGNFGVAKLMRN---RDTRELVAMKFIERGYRIDENVF 360 +N + E+ ++ + ++ +G+G +G L+R D +L AMK + + + Sbjct: 19 ANLTGHEEKVSVENFALLKVLGTGAYGKVFLVRKTGGHDAGKLYAMKVLRKAALVQRAKT 78 Query: 361 REIVN-HRSL-----RHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEA 522 +E RS+ + P ++ T L ++++Y +GGE+F + F E E Sbjct: 79 QEHTRTERSVLELVRQAPFLVTLHYAFQTDAKLHLILDYVSGGEMFTHLYQRQYFKEAEV 138 Query: 523 RYFFQQLVCGVSFCHAM 573 R + ++V + H + Sbjct: 139 RVYGGEIVLALEHLHKL 155
>KCC1G_MOUSE (Q91VB2) Calcium/calmodulin-dependent protein kinase type 1G (EC| 2.7.11.17) (CaM kinase IG) (CaM kinase I gamma) (CaMKI gamma) (CaMKI-gamma) (CaM-KI gamma) (CaMKIG) (CaMK-like CREB kinase III) (CLICK III) Length = 477 Score = 67.4 bits (163), Expect = 3e-11 Identities = 35/107 (32%), Positives = 62/107 (57%), Gaps = 1/107 (0%) Frame = +1 Query: 250 IGSGNFGVAKLMRNRDTRELVAMKFIERGYRI-DENVFREIVNHRSLRHPNIIRFKEVVL 426 +GSG F L++ R T +L A+K I++ D ++ EI + ++H NI+ +++ Sbjct: 29 LGSGAFSEVFLVKQRVTGKLFALKCIKKSPAFRDSSLENEIAVLKRIKHENIVTLEDIYE 88 Query: 427 TPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCH 567 + TH +VM+ +GGELF+RI + G + E +A QQ++ V + H Sbjct: 89 STTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKYLH 135
>KCC1G_RAT (Q7TNJ7) Calcium/calmodulin-dependent protein kinase type 1G (EC| 2.7.11.17) (CaM kinase IG) (CaM kinase I gamma) (CaMKI gamma) (CaMKI-gamma) (CaM-KI gamma) (CaMKIG) (CaMK-like CREB kinase III) (CLICK III) Length = 476 Score = 67.4 bits (163), Expect = 3e-11 Identities = 35/107 (32%), Positives = 62/107 (57%), Gaps = 1/107 (0%) Frame = +1 Query: 250 IGSGNFGVAKLMRNRDTRELVAMKFIERGYRI-DENVFREIVNHRSLRHPNIIRFKEVVL 426 +GSG F L++ R T +L A+K I++ D ++ EI + ++H NI+ +++ Sbjct: 29 LGSGAFSEVFLVKQRVTGKLFALKCIKKSPAFRDSSLENEIAVLKRIKHENIVTLEDIYE 88 Query: 427 TPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCH 567 + TH +VM+ +GGELF+RI + G + E +A QQ++ V + H Sbjct: 89 STTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKYLH 135
>KCC1G_HUMAN (Q96NX5) Calcium/calmodulin-dependent protein kinase type 1G (EC| 2.7.11.17) (CaM kinase IG) (CaM kinase I gamma) (CaMKI gamma) (CaMKI-gamma) (CaM-KI gamma) (CaMKIG) (CaMK-like CREB kinase III) (CLICK III) Length = 476 Score = 67.4 bits (163), Expect = 3e-11 Identities = 35/107 (32%), Positives = 62/107 (57%), Gaps = 1/107 (0%) Frame = +1 Query: 250 IGSGNFGVAKLMRNRDTRELVAMKFIERGYRI-DENVFREIVNHRSLRHPNIIRFKEVVL 426 +GSG F L++ R T +L A+K I++ D ++ EI + ++H NI+ +++ Sbjct: 29 LGSGAFSEVFLVKQRLTGKLFALKCIKKSPAFRDSSLENEIAVLKKIKHENIVTLEDIYE 88 Query: 427 TPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCH 567 + TH +VM+ +GGELF+RI + G + E +A QQ++ V + H Sbjct: 89 STTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKYLH 135
>CDR2_SCHPO (P87050) Mitosis inducer protein kinase cdr2 (EC 2.7.11.1)| Length = 775 Score = 67.4 bits (163), Expect = 3e-11 Identities = 34/112 (30%), Positives = 62/112 (55%), Gaps = 4/112 (3%) Frame = +1 Query: 250 IGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDEN----VFREIVNHRSLRHPNIIRFKE 417 +GSG ++L ++R+T +L +K I + + + E+V R + HPN+++ + Sbjct: 16 LGSGGPNSSRLAKHRETGQLAVVKPIVGWSELTSSQQARIEGELVLLRLIEHPNVLQLID 75 Query: 418 VVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCHAM 573 V+ L +V+EY GGELF+ + G F E + F Q++CG+ +CH + Sbjct: 76 VISAQEQLFVVVEYMPGGELFDCMLRKGSFTEQDTAKFLWQILCGLEYCHKL 127
>NEK3_MOUSE (Q9R0A5) Serine/threonine-protein kinase Nek3 (EC 2.7.11.1)| (NimA-related protein kinase 3) Length = 511 Score = 67.4 bits (163), Expect = 3e-11 Identities = 43/117 (36%), Positives = 59/117 (50%), Gaps = 2/117 (1%) Frame = +1 Query: 223 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHRSLRHPNI 402 MD Y +R IG G+FG A L+ + + AMK I + +E V ++HPNI Sbjct: 1 MDNYTVLRVIGQGSFGRALLVLQESSNQTFAMKEIRLLKSDTQTSRKEAVLLAKMKHPNI 60 Query: 403 IRFKEVVLTPTHLGIVMEYAAGGELFERICD--AGRFHEDEARYFFQQLVCGVSFCH 567 + FKE +L IVMEY GG+L +RI F ED +F Q+ GV+ H Sbjct: 61 VAFKESFEAEGYLYIVMEYCDGGDLMQRIKQQKGNLFPEDTILNWFIQICLGVNHIH 117
>MELK_MOUSE (Q61846) Maternal embryonic leucine zipper kinase (EC 2.7.11.1)| (Protein kinase PK38) (mPK38) Length = 643 Score = 67.0 bits (162), Expect = 4e-11 Identities = 40/115 (34%), Positives = 63/115 (54%), Gaps = 2/115 (1%) Frame = +1 Query: 232 YEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDE--NVFREIVNHRSLRHPNII 405 YE IG+G F KL + T E+VA+K +++ + V EI +SLRH +I Sbjct: 11 YELYETIGTGGFAKVKLACHVLTGEMVAIKIMDKNALGSDLPRVKTEIDALKSLRHQHIC 70 Query: 406 RFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCHA 570 + V+ T + +V+EY GGELF+ I R E+E R F+Q++ V++ H+ Sbjct: 71 QLYHVLETKNKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQILSAVAYVHS 125
>CDC2_VIGAC (Q41639) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) Length = 294 Score = 67.0 bits (162), Expect = 4e-11 Identities = 38/121 (31%), Positives = 68/121 (56%), Gaps = 5/121 (4%) Frame = +1 Query: 223 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFI---ERGYRIDENVFREIVNHRSLRH 393 M++YE V +IG G +GV R+R T E +A+K I + + REI + ++H Sbjct: 1 MEQYEKVEKIGEGTYGVVYKARDRVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQH 60 Query: 394 PNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHED--EARYFFQQLVCGVSFCH 567 NI+R ++VV + L +V EY +L + + + F +D + + F Q++CG+++CH Sbjct: 61 RNIVRLQDVVHSEKRLYLVFEY-LDLDLKKHMDSSPEFVKDPRQVKMFLYQILCGIAYCH 119 Query: 568 A 570 + Sbjct: 120 S 120
>SRK1_SCHPO (O94547) Serine/threonine-protein kinase srk1 (EC 2.7.11.1)| (Sty1-regulated kinase 1) Length = 580 Score = 66.6 bits (161), Expect = 5e-11 Identities = 41/130 (31%), Positives = 69/130 (53%), Gaps = 14/130 (10%) Frame = +1 Query: 220 GMDKYEPVREIGSGNFG-VAKLMRNRDTRELVAMKFIERGYRIDE-------------NV 357 G+++Y ++++G G F V K + NR T E VA+K ++R + N+ Sbjct: 120 GLEQYTLLQKMGDGAFSNVYKAIHNR-TGEKVAIKVVQRAQPNTDPRDPRKRQGVESHNI 178 Query: 358 FREIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQ 537 +E+ R ++HPNII+ E + TP + +V+E A GGELF +I F ED +R+ Sbjct: 179 LKEVQIMRRVKHPNIIQLLEFIQTPEYYYLVLELADGGELFHQIVRLTYFSEDLSRHVIT 238 Query: 538 QLVCGVSFCH 567 Q+ + + H Sbjct: 239 QVAHAIRYLH 248
>STK6L_XENLA (Q91819) Serine/threonine-protein kinase Eg2-like (EC 2.7.11.1)| (p46XlEg22) Length = 408 Score = 66.6 bits (161), Expect = 5e-11 Identities = 33/120 (27%), Positives = 64/120 (53%), Gaps = 4/120 (3%) Frame = +1 Query: 223 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYR----IDENVFREIVNHRSLR 390 ++ +E R +G G FG L R R+++ ++A+K + + ++ + RE+ LR Sbjct: 137 LEDFEIGRPLGKGKFGNVYLARERESKFILALKVLFKSQLEKAGVEHQLRREVEIQSHLR 196 Query: 391 HPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCHA 570 HPNI+R + + ++++YA GGELF + RF + + + +QL + +CH+ Sbjct: 197 HPNILRLYGYFHDASRVYLILDYAPGGELFRELQKCTRFDDQRSALYIKQLAEALLYCHS 256
>KAPCG_HUMAN (P22612) cAMP-dependent protein kinase, gamma-catalytic subunit (EC| 2.7.11.11) (PKA C-gamma) Length = 350 Score = 66.6 bits (161), Expect = 5e-11 Identities = 35/120 (29%), Positives = 66/120 (55%), Gaps = 4/120 (3%) Frame = +1 Query: 226 DKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHR----SLRH 393 D++E +R +G G+FG L+R+++T AMK + + + I+N + ++ Sbjct: 41 DQFERLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAIDF 100 Query: 394 PNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCHAM 573 P +++ + ++L +VMEY GGE+F R+ GRF E A ++ Q+V V + H++ Sbjct: 101 PFLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLHSL 160
>KAPCB_HUMAN (P22694) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 66.6 bits (161), Expect = 5e-11 Identities = 32/126 (25%), Positives = 68/126 (53%), Gaps = 4/126 (3%) Frame = +1 Query: 208 RERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHR-- 381 + +G++ +E + +G+G+FG L++++ T + AMK +++ + +N + Sbjct: 35 QNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRI 94 Query: 382 --SLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGV 555 ++ P ++R + ++L +VMEY GGE+F + GRF E AR++ Q+V Sbjct: 95 LQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTF 154 Query: 556 SFCHAM 573 + H++ Sbjct: 155 EYLHSL 160
>STK6_XENLA (Q91820) Serine/threonine-protein kinase Eg2 (EC 2.7.11.1) (pEg2)| (p46Eg265) Length = 407 Score = 66.6 bits (161), Expect = 5e-11 Identities = 33/120 (27%), Positives = 64/120 (53%), Gaps = 4/120 (3%) Frame = +1 Query: 223 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYR----IDENVFREIVNHRSLR 390 ++ +E R +G G FG L R R+++ ++A+K + + ++ + RE+ LR Sbjct: 137 LEDFEIGRPLGKGKFGNVYLARERESKFILALKVLFKSQLEKAGVEHQLRREVEIQSHLR 196 Query: 391 HPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCHA 570 HPNI+R + + ++++YA GGELF + RF + + + +QL + +CH+ Sbjct: 197 HPNILRLYGYFHDASRVYLILDYAPGGELFRELQKCTRFDDQRSAMYIKQLAEALLYCHS 256
>KCC1_YEAST (P27466) Calcium/calmodulin-dependent protein kinase I (EC| 2.7.11.17) Length = 446 Score = 66.6 bits (161), Expect = 5e-11 Identities = 38/119 (31%), Positives = 67/119 (56%), Gaps = 5/119 (4%) Frame = +1 Query: 229 KYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIER----GYRID-ENVFREIVNHRSLRH 393 KY + +G+G FGV + +N +T E VA+K + + G ++ E ++ E+ + L H Sbjct: 36 KYVFGKTLGAGTFGVVRQAKNTETGEDVAVKILIKKALKGNKVQLEALYDELDILQRLHH 95 Query: 394 PNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCHA 570 PNI+ FK+ + I+ + A GGELF+RI G+F E++A +++ V + H+ Sbjct: 96 PNIVAFKDWFESKDKFYIITQLAKGGELFDRILKKGKFTEEDAVRILVEILSAVKYMHS 154
>CDPK1_PLAFK (P62343) Calcium-dependent protein kinase 1 (EC 2.7.11.1) (PfCPK)| (PfCDPK1) Length = 523 Score = 66.6 bits (161), Expect = 5e-11 Identities = 41/138 (29%), Positives = 69/138 (50%), Gaps = 16/138 (11%) Frame = +1 Query: 202 RERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGY-------------- 339 R++E + Y VR++GSG +G L R + A+K I++ Sbjct: 45 RKKEGKIGESYFKVRKLGSGAYGEVLLCREKHGHGEKAIKVIKKSQFDKMKYSITNKIEC 104 Query: 340 --RIDENVFREIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHE 513 +I E ++ EI +SL HPNII+ +V + +V E+ GGELFE+I + +F E Sbjct: 105 DDKIHEEIYNEISLLKSLDHPNIIKLFDVFEDKKYFYLVTEFYEGGELFEQIINRHKFDE 164 Query: 514 DEARYFFQQLVCGVSFCH 567 +A +Q++ G+ + H Sbjct: 165 CDAANIMKQILSGICYLH 182
>CDPK1_PLAF7 (P62344) Calcium-dependent protein kinase 1 (EC 2.7.11.1)| Length = 523 Score = 66.6 bits (161), Expect = 5e-11 Identities = 41/138 (29%), Positives = 69/138 (50%), Gaps = 16/138 (11%) Frame = +1 Query: 202 RERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGY-------------- 339 R++E + Y VR++GSG +G L R + A+K I++ Sbjct: 45 RKKEGKIGESYFKVRKLGSGAYGEVLLCREKHGHGEKAIKVIKKSQFDKMKYSITNKIEC 104 Query: 340 --RIDENVFREIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHE 513 +I E ++ EI +SL HPNII+ +V + +V E+ GGELFE+I + +F E Sbjct: 105 DDKIHEEIYNEISLLKSLDHPNIIKLFDVFEDKKYFYLVTEFYEGGELFEQIINRHKFDE 164 Query: 514 DEARYFFQQLVCGVSFCH 567 +A +Q++ G+ + H Sbjct: 165 CDAANIMKQILSGICYLH 182
>KAPB2_BOVIN (P24256) cAMP-dependent protein kinase, beta-2-catalytic subunit| (EC 2.7.11.11) (PKA C-beta-2) Length = 397 Score = 66.2 bits (160), Expect = 6e-11 Identities = 32/123 (26%), Positives = 67/123 (54%), Gaps = 4/123 (3%) Frame = +1 Query: 217 SGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHR----S 384 +G++ +E + +G+G+FG L++++ T + AMK +++ + +N + + Sbjct: 85 AGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQA 144 Query: 385 LRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFC 564 + P ++R + ++L +VMEY GGE+F + GRF E AR++ Q+V + Sbjct: 145 VNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYL 204 Query: 565 HAM 573 H++ Sbjct: 205 HSL 207
>KAPB1_BOVIN (P05131) cAMP-dependent protein kinase, beta-1-catalytic subunit| (EC 2.7.11.11) (PKA C-beta-1) Length = 350 Score = 66.2 bits (160), Expect = 6e-11 Identities = 32/123 (26%), Positives = 67/123 (54%), Gaps = 4/123 (3%) Frame = +1 Query: 217 SGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHR----S 384 +G++ +E + +G+G+FG L++++ T + AMK +++ + +N + + Sbjct: 38 AGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQA 97 Query: 385 LRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFC 564 + P ++R + ++L +VMEY GGE+F + GRF E AR++ Q+V + Sbjct: 98 VNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYL 157 Query: 565 HAM 573 H++ Sbjct: 158 HSL 160
>STK36_PONPY (Q5RAJ5) Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused| homolog) Length = 1315 Score = 66.2 bits (160), Expect = 6e-11 Identities = 41/119 (34%), Positives = 66/119 (55%), Gaps = 3/119 (2%) Frame = +1 Query: 223 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDE---NVFREIVNHRSLRH 393 M+KY + IG G+FG R + + ++VA+KFI + R ++ N+ REI R LRH Sbjct: 1 MEKYHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLRH 60 Query: 394 PNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCHA 570 PNI+ + T + +V +YA GEL + + D G+ ED+ + QLV + + H+ Sbjct: 61 PNIVHMLDSFETDKEVVVVTDYAE-GELLQILEDDGKLPEDQVQAIAAQLVSALYYLHS 118
>CDPK1_PLAYO (Q7RAH3) Calcium-dependent protein kinase 1 (EC 2.7.11.1)| Length = 534 Score = 66.2 bits (160), Expect = 6e-11 Identities = 39/136 (28%), Positives = 69/136 (50%), Gaps = 14/136 (10%) Frame = +1 Query: 202 RERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGY-------------- 339 R++E + Y VR++GSG +G L + ++ A+K I++ Sbjct: 46 RKKEGKIGESYFKVRKLGSGAYGEVLLCKEKNGHSEKAIKVIKKSQFDKGRYNDDNKNIE 105 Query: 340 RIDENVFREIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDE 519 + E ++ EI +SL HPNII+ +V + +V E+ GGELFE+I + +F E + Sbjct: 106 KFHEEIYNEISLLKSLDHPNIIKLFDVFEDKKYFYLVTEFYEGGELFEQIINRHKFDECD 165 Query: 520 ARYFFQQLVCGVSFCH 567 A +Q++ G+ + H Sbjct: 166 AANIMKQILSGICYLH 181
>CDC2_VIGUN (P52389) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) Length = 294 Score = 66.2 bits (160), Expect = 6e-11 Identities = 38/121 (31%), Positives = 68/121 (56%), Gaps = 5/121 (4%) Frame = +1 Query: 223 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFI---ERGYRIDENVFREIVNHRSLRH 393 M++YE V +IG G +GV R+R T E +A+K I + + REI + ++H Sbjct: 1 MEQYEKVEKIGEGTYGVVYKARDRVTDETIALKKIRLEQEDEGVPSTAIREISLLKEMQH 60 Query: 394 PNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHED--EARYFFQQLVCGVSFCH 567 NI+R ++VV + L +V EY +L + + + F +D + + F Q++CG+++CH Sbjct: 61 RNIVRLQDVVHSEKRLYLVFEY-LDLDLKKHMDSSPEFVKDPRQVKMFLYQILCGIAYCH 119 Query: 568 A 570 + Sbjct: 120 S 120
>CDC22_MEDSA (Q05006) Cell division control protein 2 homolog 2 (EC 2.7.11.22)| Length = 294 Score = 66.2 bits (160), Expect = 6e-11 Identities = 38/121 (31%), Positives = 68/121 (56%), Gaps = 5/121 (4%) Frame = +1 Query: 223 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFI---ERGYRIDENVFREIVNHRSLRH 393 M++YE V +IG G +GV R+R T E +A+K I + + REI + ++H Sbjct: 1 MEQYEKVEKIGEGTYGVVYKARDRATNETIALKKIRLEQEDEGVPSTAIREISLLKEMQH 60 Query: 394 PNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHED--EARYFFQQLVCGVSFCH 567 NI+R ++VV + L +V EY +L + + + F +D + + F Q++CG+++CH Sbjct: 61 RNIVRLQDVVHSEKRLYLVFEY-LDLDLKKFMDSSPEFAKDQRQIKMFLYQILCGIAYCH 119 Query: 568 A 570 + Sbjct: 120 S 120
>AURKB_RAT (O55099) Serine/threonine-protein kinase 12 (EC 2.7.11.1) (Aurora-| and Ipl1-like midbody-associated protein 1) (AIM-1) (Aurora-B) Length = 343 Score = 66.2 bits (160), Expect = 6e-11 Identities = 35/127 (27%), Positives = 64/127 (50%), Gaps = 4/127 (3%) Frame = +1 Query: 199 SRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGY----RIDENVFRE 366 S+ R+ +D +E R +G G FG L R + +R +VA+K + + ++ + RE Sbjct: 69 SQSRQPFTIDNFEIGRPLGKGKFGNVYLAREKKSRFIVALKILFKSQIEKEGVEHQLRRE 128 Query: 367 IVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLV 546 I L+HPNI++ + +++EYA GEL++ + +G F E ++L Sbjct: 129 IEIQAHLKHPNILQLYNYFYDQQRIYLILEYAPRGELYKELQKSGTFDEQRTATIMEELS 188 Query: 547 CGVSFCH 567 + +CH Sbjct: 189 DALMYCH 195
>AURKC_HUMAN (Q9UQB9) Serine/threonine-protein kinase 13 (EC 2.7.11.1)| (Aurora/Ipl1/Eg2 protein 2) (Aurora/Ipl1-related kinase 3) (Aurora-C) Length = 309 Score = 66.2 bits (160), Expect = 6e-11 Identities = 39/144 (27%), Positives = 72/144 (50%), Gaps = 6/144 (4%) Frame = +1 Query: 154 PASREIATHRKTSNR--SRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFI 327 PA E+AT +T+ + S R +D +E R +G G FG L R +++ +VA+K + Sbjct: 15 PAGEELATANQTAQQPSSPAMRRLTVDDFEIGRPLGKGKFGNVYLARLKESHFIVALKVL 74 Query: 328 ERGY----RIDENVFREIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICD 495 + ++ + REI L+HPNI+R + +++EYA GEL++ + Sbjct: 75 FKSQIEKEGLEHQLRREIEIQAHLQHPNILRLYNYFHDARRVYLILEYAPRGELYKELQK 134 Query: 496 AGRFHEDEARYFFQQLVCGVSFCH 567 + + E ++L +++CH Sbjct: 135 SEKLDEQRTATIIEELADALTYCH 158
>MELK_HUMAN (Q14680) Maternal embryonic leucine zipper kinase (EC 2.7.11.1)| (hMELK) (Protein kinase PK38) (hPK38) Length = 651 Score = 66.2 bits (160), Expect = 6e-11 Identities = 39/115 (33%), Positives = 63/115 (54%), Gaps = 2/115 (1%) Frame = +1 Query: 232 YEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDE--NVFREIVNHRSLRHPNII 405 YE IG+G F KL + T E+VA+K +++ + + EI ++LRH +I Sbjct: 11 YELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTLGSDLPRIKTEIEALKNLRHQHIC 70 Query: 406 RFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCHA 570 + V+ T + +V+EY GGELF+ I R E+E R F+Q+V V++ H+ Sbjct: 71 QLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHS 125
>AKT1_BOVIN (Q01314) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (Protein kinase B) (PKB) Length = 480 Score = 65.9 bits (159), Expect = 8e-11 Identities = 39/128 (30%), Positives = 67/128 (52%), Gaps = 4/128 (3%) Frame = +1 Query: 199 SRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRI-DENVFREIVN 375 ++ + R M+++E V+ +G G FG L++ + T AMK +++ + + V + Sbjct: 139 AKPKHRVTMNEFEYVKLLGKGTFGKVILVKEKATAAYYAMKILKKEVIVAKDEVAHTLTE 198 Query: 376 HRSL---RHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLV 546 +R L RHP++ K T L VMEYA GGELF + F ED AR++ ++V Sbjct: 199 NRVLQNSRHPSLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIV 258 Query: 547 CGVSFCHA 570 + + H+ Sbjct: 259 SALDYLHS 266
>CDR1_SCHPO (P07334) Mitosis inducer protein kinase cdr1 (EC 2.7.11.1) (Protein| kinase nim1) Length = 593 Score = 65.9 bits (159), Expect = 8e-11 Identities = 37/121 (30%), Positives = 64/121 (52%) Frame = +1 Query: 205 ERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHRS 384 +R ++ + + + +G+G+ +L ++ T +L A+K I Y ++ EI+ R Sbjct: 3 KRHKNTIGVWRLGKTLGTGSTSCVRLAKHAKTGDLAAIKIIPIRYA---SIGMEILMMRL 59 Query: 385 LRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFC 564 LRHPNI+R +V H+ + +EY GELF I G E EA ++ Q++ V+ C Sbjct: 60 LRHPNILRLYDVWTDHQHMYLALEYVPDGELFHYIRKHGPLSEREAAHYLSQILDAVAHC 119 Query: 565 H 567 H Sbjct: 120 H 120
>KRAC_DICDI (P54644) RAC-family serine/threonine-protein kinase homolog (EC| 2.7.11.1) Length = 444 Score = 65.9 bits (159), Expect = 8e-11 Identities = 33/126 (26%), Positives = 64/126 (50%), Gaps = 4/126 (3%) Frame = +1 Query: 202 RERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHR 381 ++ E+ G+ +E + +G G+FG +R +DT E+ AMK + + + ++ N ++ R Sbjct: 110 KKSEKVGVADFELLNLVGKGSFGKVIQVRKKDTGEVYAMKVLSKKHIVEHNEVEHTLSER 169 Query: 382 SL----RHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVC 549 ++ HP ++ T L +++Y GGELF + +F ED RY+ ++V Sbjct: 170 NILQKINHPFLVNLNYSFQTEDKLYFILDYVNGGELFYHLQKDKKFTEDRVRYYGAEIVL 229 Query: 550 GVSFCH 567 + H Sbjct: 230 ALEHLH 235
>DUN1_YEAST (P39009) DNA damage response protein kinase DUN1 (EC 2.7.11.1)| Length = 513 Score = 65.5 bits (158), Expect = 1e-10 Identities = 44/149 (29%), Positives = 73/149 (48%), Gaps = 9/149 (6%) Frame = +1 Query: 148 SAPASREIATHRKTSNRSRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFI 327 SA +S+ T ++ R S DKY +E+G+G++ + K +N+ T + VA+K Sbjct: 172 SATSSQNATTSAAIRKLNKTRPVSFFDKYLLGKELGAGHYALVKEAKNKKTGQQVAVKIF 231 Query: 328 ERGYRIDENV---FREIVNH-RSLRHPNIIRFKEVVLTPTHLG-----IVMEYAAGGELF 480 D+ FRE N ++HPNI+ + + P +V+E GELF Sbjct: 232 HAQQNDDQKKNKQFREETNILMRVQHPNIVNLLDSFVEPISKSQIQKYLVLEKIDDGELF 291 Query: 481 ERICDAGRFHEDEARYFFQQLVCGVSFCH 567 ERI +DE++ F+QL+ G+ + H Sbjct: 292 ERIVRKTCLRQDESKALFKQLLTGLKYLH 320
>KCC2_YEAST (P22517) Calcium/calmodulin-dependent protein kinase II (EC| 2.7.11.17) Length = 447 Score = 65.5 bits (158), Expect = 1e-10 Identities = 39/114 (34%), Positives = 60/114 (52%), Gaps = 5/114 (4%) Frame = +1 Query: 244 REIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENV-----FREIVNHRSLRHPNIIR 408 R +G+G+FGV + R T E VA+K + + NV + E+ + L HPNI+ Sbjct: 51 RTLGAGSFGVVRQARKLSTNEDVAIKILLKKALQGNNVQLQMLYEELSILQKLSHPNIVS 110 Query: 409 FKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCHA 570 FK+ + IV + A GGELF+RI G+F E +A Q++ V + H+ Sbjct: 111 FKDWFESKDKFYIVTQLATGGELFDRILSRGKFTEVDAVEIIVQILGAVEYMHS 164
>KAPCB_RAT (P68182) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 65.5 bits (158), Expect = 1e-10 Identities = 32/123 (26%), Positives = 67/123 (54%), Gaps = 4/123 (3%) Frame = +1 Query: 217 SGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHR----S 384 +G++ +E + +G+G+FG L++++ T + AMK +++ + +N + + Sbjct: 38 AGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQA 97 Query: 385 LRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFC 564 + P ++R + ++L +VMEY GGE+F + GRF E AR++ Q+V + Sbjct: 98 VEFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYL 157 Query: 565 HAM 573 H++ Sbjct: 158 HSL 160
>KAPCB_MOUSE (P68181) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 65.5 bits (158), Expect = 1e-10 Identities = 32/123 (26%), Positives = 67/123 (54%), Gaps = 4/123 (3%) Frame = +1 Query: 217 SGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHR----S 384 +G++ +E + +G+G+FG L++++ T + AMK +++ + +N + + Sbjct: 38 AGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQA 97 Query: 385 LRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFC 564 + P ++R + ++L +VMEY GGE+F + GRF E AR++ Q+V + Sbjct: 98 VEFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYL 157 Query: 565 HAM 573 H++ Sbjct: 158 HSL 160
>KAPCB_CRIGR (P68180) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 65.5 bits (158), Expect = 1e-10 Identities = 32/123 (26%), Positives = 67/123 (54%), Gaps = 4/123 (3%) Frame = +1 Query: 217 SGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHR----S 384 +G++ +E + +G+G+FG L++++ T + AMK +++ + +N + + Sbjct: 38 AGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQA 97 Query: 385 LRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFC 564 + P ++R + ++L +VMEY GGE+F + GRF E AR++ Q+V + Sbjct: 98 VEFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYL 157 Query: 565 HAM 573 H++ Sbjct: 158 HSL 160
>STK36_MOUSE (Q69ZM6) Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused| homolog) Length = 1268 Score = 65.5 bits (158), Expect = 1e-10 Identities = 41/119 (34%), Positives = 66/119 (55%), Gaps = 3/119 (2%) Frame = +1 Query: 223 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDE---NVFREIVNHRSLRH 393 M+KY + IG G+FG R + + ++VA+KFI + R ++ N+ REI R L H Sbjct: 1 MEKYHVLEMIGEGSFGRVYKGRKKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLWH 60 Query: 394 PNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCHA 570 PNI+ + T + +V +YA GELF+ + D G+ ED+ + QLV + + H+ Sbjct: 61 PNIVHMLDSFETDKEVVVVTDYAE-GELFQILEDDGKLPEDQVQAIAAQLVSALYYLHS 118
>KPK1_ARATH (P42818) Serine/threonine-protein kinase AtPK1/AtPK6 (EC 2.7.11.1)| Length = 465 Score = 65.5 bits (158), Expect = 1e-10 Identities = 36/120 (30%), Positives = 64/120 (53%), Gaps = 4/120 (3%) Frame = +1 Query: 220 GMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHRSLR--- 390 G+D +E ++ +G G FG +R ++T E+ AMK + + + +++N + R + Sbjct: 130 GIDDFEVMKVVGKGAFGKVYQVRKKETSEIYAMKVMRKDHIMEKNHAEYMKAERDILTKI 189 Query: 391 -HPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCH 567 HP I++ K T L +V+++ GG LF ++ G F ED AR + ++V VS H Sbjct: 190 DHPFIVQLKYSFQTKYRLYLVLDFINGGHLFFQLYHQGLFREDLARVYTAEIVSAVSHLH 249
>KS6A5_PONPY (Q5R4K3) Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1)| Length = 802 Score = 65.5 bits (158), Expect = 1e-10 Identities = 38/109 (34%), Positives = 58/109 (53%), Gaps = 1/109 (0%) Frame = +1 Query: 244 REIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHRSLR-HPNIIRFKEV 420 + +G G+F + + ++ + + A+K I + R++ N +EI + HPNI++ EV Sbjct: 430 KPLGEGSFSICRKCVHKKSNQAFAVKIISK--RMEANTQKEITALKLCEGHPNIVKLHEV 487 Query: 421 VLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCH 567 H +VME GGELFERI F E EA Y ++LV VS H Sbjct: 488 FHDQLHTFLVMELLNGGELFERIKKKKHFSETEASYIMRKLVSAVSHMH 536 Score = 59.7 bits (143), Expect = 6e-09 Identities = 35/140 (25%), Positives = 71/140 (50%), Gaps = 10/140 (7%) Frame = +1 Query: 184 KTSNRSRERERSGMDKYEPVREIGSGNFGVAKLMR---NRDTRELVAMKFIERGYRIDE- 351 +T+N + ER G++ +E ++ +G+G +G L+R DT +L AMK +++ + + Sbjct: 33 RTANLTGHAERVGIENFELLKVLGTGAYGKVFLVRKISGHDTGKLYAMKVLKKATIVQKA 92 Query: 352 ------NVFREIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHE 513 R+++ H + + P ++ T T L ++++Y GGELF + RF E Sbjct: 93 KTTEHTRTERQVLEH-TRQSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTE 151 Query: 514 DEARYFFQQLVCGVSFCHAM 573 E + + ++V + H + Sbjct: 152 HEVQIYVGEIVLALEHLHKL 171
>KS6A5_HUMAN (O75582) Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1) (Nuclear| mitogen-and stress-activated protein kinase 1) (90 kDa ribosomal protein S6 kinase 5) (RSK-like protein kinase) (RSKL) Length = 802 Score = 65.5 bits (158), Expect = 1e-10 Identities = 38/109 (34%), Positives = 58/109 (53%), Gaps = 1/109 (0%) Frame = +1 Query: 244 REIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHRSLR-HPNIIRFKEV 420 + +G G+F + + ++ + + A+K I + R++ N +EI + HPNI++ EV Sbjct: 430 KPLGEGSFSICRKCVHKKSNQAFAVKIISK--RMEANTQKEITALKLCEGHPNIVKLHEV 487 Query: 421 VLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCH 567 H +VME GGELFERI F E EA Y ++LV VS H Sbjct: 488 FHDQLHTFLVMELLNGGELFERIKKKKHFSETEASYIMRKLVSAVSHMH 536 Score = 57.4 bits (137), Expect = 3e-08 Identities = 34/140 (24%), Positives = 70/140 (50%), Gaps = 10/140 (7%) Frame = +1 Query: 184 KTSNRSRERERSGMDKYEPVREIGSGNFGVAKLMR---NRDTRELVAMKFIERGYRIDE- 351 +T+N + E+ G++ +E ++ +G+G +G L+R DT +L AMK +++ + + Sbjct: 33 RTANLTGHAEKVGIENFELLKVLGTGAYGKVFLVRKISGHDTGKLYAMKVLKKATIVQKA 92 Query: 352 ------NVFREIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHE 513 R+++ H + P ++ T T L ++++Y GGELF + RF E Sbjct: 93 KTTEHTRTERQVLEH-IRQSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTE 151 Query: 514 DEARYFFQQLVCGVSFCHAM 573 E + + ++V + H + Sbjct: 152 HEVQIYVGEIVLALEHLHKL 171
>DCAK1_HUMAN (O15075) Serine/threonine-protein kinase DCAMKL1 (EC 2.7.11.1)| (Doublecortin-like and CAM kinase-like 1) Length = 740 Score = 65.1 bits (157), Expect = 1e-10 Identities = 38/118 (32%), Positives = 62/118 (52%), Gaps = 2/118 (1%) Frame = +1 Query: 226 DKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGY-RIDENVFR-EIVNHRSLRHPN 399 ++Y+ R IG GNF V K R T A+K I++ R E++ + E+ R ++HPN Sbjct: 388 ERYKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRVKHPN 447 Query: 400 IIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCHAM 573 I+ E + PT L +VME GG+LF+ I ++ E +A L + + H++ Sbjct: 448 IVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSL 505
>KS6A4_HUMAN (O75676) Ribosomal protein S6 kinase alpha-4 (EC 2.7.11.1) (Nuclear| mitogen-and stress-activated protein kinase 2) (90 kDa ribosomal protein S6 kinase 4) (Ribosomal protein kinase B) (RSKB) Length = 772 Score = 65.1 bits (157), Expect = 1e-10 Identities = 41/116 (35%), Positives = 58/116 (50%), Gaps = 1/116 (0%) Frame = +1 Query: 223 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHRSLR-HPN 399 +D EP +G G+F V + R R + + A+K + R R++ N RE+ R + HPN Sbjct: 410 LDLREPA--LGQGSFSVCRRCRQRQSGQEFAVKILSR--RLEANTQREVAALRLCQSHPN 465 Query: 400 IIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCH 567 ++ EV H +V+E GGEL E I F E EA + LV VSF H Sbjct: 466 VVNLHEVHHDQLHTYLVLELLRGGELLEHIRKKRHFSESEASQILRSLVSAVSFMH 521 Score = 45.4 bits (106), Expect = 1e-04 Identities = 30/137 (21%), Positives = 63/137 (45%), Gaps = 9/137 (6%) Frame = +1 Query: 190 SNRSRERERSGMDKYEPVREIGSGNFGVAKLMRN---RDTRELVAMKFIERGYRIDENVF 360 +N + E+ ++ +E ++ +G+G +G L+R D +L AMK + + + Sbjct: 19 ANLTGHEEKVSVENFELLKVLGTGAYGKVFLVRKAGGHDAGKLYAMKVLRKAALVQRAKT 78 Query: 361 REIVN-HRSL-----RHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEA 522 +E RS+ + P ++ T L ++++Y +GGE+F + F E E Sbjct: 79 QEHTRTERSVLELVRQAPFLVTLHYAFQTDAKLHLILDYVSGGEMFTHLYQRQYFKEAEV 138 Query: 523 RYFFQQLVCGVSFCHAM 573 R + ++V + H + Sbjct: 139 RVYGGEIVLALEHLHKL 155
>DCAK1_RAT (O08875) Serine/threonine-protein kinase DCAMKL1 (EC 2.7.11.1)| (Doublecortin-like and CAM kinase-like 1) (Calcium/calmodulin-dependent protein kinase type I-like CPG16) Length = 433 Score = 65.1 bits (157), Expect = 1e-10 Identities = 38/118 (32%), Positives = 62/118 (52%), Gaps = 2/118 (1%) Frame = +1 Query: 226 DKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGY-RIDENVFR-EIVNHRSLRHPN 399 ++Y+ R IG GNF V K R T A+K I++ R E++ + E+ R ++HPN Sbjct: 81 ERYKVGRTIGDGNFAVVKECIERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRVKHPN 140 Query: 400 IIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCHAM 573 I+ E + PT L +VME GG+LF+ I ++ E +A L + + H++ Sbjct: 141 IVLLIEEMDVPTELYLVMELVKGGDLFDAITSTSKYTERDASGMLYNLASAIKYLHSL 198
>KAPCB_PIG (P05383) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 65.1 bits (157), Expect = 1e-10 Identities = 32/123 (26%), Positives = 67/123 (54%), Gaps = 4/123 (3%) Frame = +1 Query: 217 SGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHR----S 384 +G++ +E + +G+G+FG L++++ T + AMK +++ + +N + + Sbjct: 38 AGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQA 97 Query: 385 LRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFC 564 + P ++R + ++L +VMEY GGE+F + GRF E AR++ Q+V + Sbjct: 98 VNFPFLVRLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYL 157 Query: 565 HAM 573 H++ Sbjct: 158 HSL 160
>KAPCA_PIG (P36887) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 65.1 bits (157), Expect = 1e-10 Identities = 31/121 (25%), Positives = 67/121 (55%), Gaps = 4/121 (3%) Frame = +1 Query: 223 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHR----SLR 390 +D++E ++ +G+G+FG L+++++T AMK +++ + +N + ++ Sbjct: 40 LDQFERIKTLGTGSFGRVMLVKHKETGNHFAMKILDKQKVVKLKQIEHTLNEKRILQAVN 99 Query: 391 HPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCHA 570 P +++ + ++L +VMEY GGE+F + GRF E AR++ Q+V + H+ Sbjct: 100 FPFLVKLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHS 159 Query: 571 M 573 + Sbjct: 160 L 160
>DCAK1_MOUSE (Q9JLM8) Serine/threonine-protein kinase DCAMKL1 (EC 2.7.11.1)| (Doublecortin-like and CAM kinase-like 1) Length = 756 Score = 65.1 bits (157), Expect = 1e-10 Identities = 38/118 (32%), Positives = 62/118 (52%), Gaps = 2/118 (1%) Frame = +1 Query: 226 DKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGY-RIDENVFR-EIVNHRSLRHPN 399 ++Y+ R IG GNF V K R T A+K I++ R E++ + E+ R ++HPN Sbjct: 404 ERYKVGRTIGDGNFAVVKECIERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRVKHPN 463 Query: 400 IIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCHAM 573 I+ E + PT L +VME GG+LF+ I ++ E +A L + + H++ Sbjct: 464 IVLLIEEMDVPTELYLVMELVKGGDLFDAITSTSKYTERDASGMLYNLASAIKYLHSL 521
>KPSH1_PINFU (Q4KTY1) Serine/threonine-protein kinase H1 homolog (EC 2.7.11.1)| Length = 415 Score = 65.1 bits (157), Expect = 1e-10 Identities = 46/135 (34%), Positives = 69/135 (51%), Gaps = 7/135 (5%) Frame = +1 Query: 190 SNRSRERERSGMD-----KYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIER--GYRID 348 SNR ++ R D KY+ IG GNF + +R T++ A+K I+R G + Sbjct: 61 SNRKVKKYRDKFDPRVTAKYDIKALIGRGNFSKVVRVEHRVTKQPYAIKMIDRVQGKEVF 120 Query: 349 ENVFREIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARY 528 E+ E+ R ++H II+ EV T + +VME A GGELF+RI G F E +A Sbjct: 121 ES---EVAVLRRVKHSYIIQLIEVFETKDKVYMVMELATGGELFDRIIAKGSFTERDATR 177 Query: 529 FFQQLVCGVSFCHAM 573 ++ GV + H + Sbjct: 178 VLNMVLDGVKYLHGL 192
>KAPCA_HUMAN (P17612) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 64.7 bits (156), Expect = 2e-10 Identities = 31/121 (25%), Positives = 67/121 (55%), Gaps = 4/121 (3%) Frame = +1 Query: 223 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHR----SLR 390 +D++E ++ +G+G+FG L+++++T AMK +++ + +N + ++ Sbjct: 40 LDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVN 99 Query: 391 HPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCHA 570 P +++ + ++L +VMEY GGE+F + GRF E AR++ Q+V + H+ Sbjct: 100 FPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHS 159 Query: 571 M 573 + Sbjct: 160 L 160
>KAPCA_CANFA (Q8MJ44) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 349 Score = 64.7 bits (156), Expect = 2e-10 Identities = 31/121 (25%), Positives = 67/121 (55%), Gaps = 4/121 (3%) Frame = +1 Query: 223 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHR----SLR 390 +D++E ++ +G+G+FG L+++++T AMK +++ + +N + ++ Sbjct: 39 LDQFERIKTLGTGSFGRVMLVKHKETGNHFAMKILDKQKVVKLKQIEHTLNEKRILQAVN 98 Query: 391 HPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCHA 570 P +++ + ++L +VMEY GGE+F + GRF E AR++ Q+V + H+ Sbjct: 99 FPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHS 158 Query: 571 M 573 + Sbjct: 159 L 159
>KPK19_ARATH (Q39030) Serine/threonine-protein kinase AtPK19 (EC 2.7.11.1)| (Ribosomal-protein S6 kinase homolog) Length = 471 Score = 64.7 bits (156), Expect = 2e-10 Identities = 36/120 (30%), Positives = 63/120 (52%), Gaps = 4/120 (3%) Frame = +1 Query: 220 GMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHRSLR--- 390 G++ +E ++ +G G FG +R +DT E+ AMK + + +++N + R + Sbjct: 136 GIEDFEVLKVVGQGAFGKVYQVRKKDTSEIYAMKVMRKDKIVEKNHAEYMKAERDILTKI 195 Query: 391 -HPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCH 567 HP I++ K T L +V+++ GG LF ++ G F ED AR + ++V VS H Sbjct: 196 DHPFIVQLKYSFQTKYRLYLVLDFINGGHLFFQLYHQGLFREDLARVYTAEIVSAVSHLH 255
>KCC1D_MOUSE (Q8BW96) Calcium/calmodulin-dependent protein kinase type 1D (EC| 2.7.11.17) (CaM kinase ID) (CaM kinase I delta) (CaMKI-delta) (CaM-KI delta) (CaMKI delta) (Camk1D) (CamKI-like protein kinase) (CKLiK) (mCKLiK) Length = 385 Score = 64.3 bits (155), Expect = 2e-10 Identities = 39/138 (28%), Positives = 73/138 (52%), Gaps = 3/138 (2%) Frame = +1 Query: 169 IATHRKTSNRSRERERSGMDKYEPVRE-IGSGNFGVAKLMRNRDTRELVAMKFIERGYRI 345 +A S+ S +++ + K +E +G+G F L + T +L A+K I + Sbjct: 1 MARENGESSSSWKKQAEDIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALK 60 Query: 346 --DENVFREIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDE 519 + ++ EI R ++H NI+ +++ +P HL +VM+ +GGELF+RI + G + E + Sbjct: 61 GKESSIENEIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKD 120 Query: 520 ARYFFQQLVCGVSFCHAM 573 A +Q++ V + H M Sbjct: 121 ASTLIRQVLDAVYYLHRM 138
>KCC1D_HUMAN (Q8IU85) Calcium/calmodulin-dependent protein kinase type 1D (EC| 2.7.11.17) (CaM kinase ID) (CaM kinase I delta) (CaMKI-delta) (CaM-KI delta) (CaMKI delta) (Camk1D) (CamKI-like protein kinase) (CKLiK) Length = 385 Score = 64.3 bits (155), Expect = 2e-10 Identities = 39/138 (28%), Positives = 73/138 (52%), Gaps = 3/138 (2%) Frame = +1 Query: 169 IATHRKTSNRSRERERSGMDKYEPVRE-IGSGNFGVAKLMRNRDTRELVAMKFIERGYRI 345 +A S+ S +++ + K +E +G+G F L + T +L A+K I + Sbjct: 1 MARENGESSSSWKKQAEDIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALK 60 Query: 346 --DENVFREIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDE 519 + ++ EI R ++H NI+ +++ +P HL +VM+ +GGELF+RI + G + E + Sbjct: 61 GKESSIENEIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKD 120 Query: 520 ARYFFQQLVCGVSFCHAM 573 A +Q++ V + H M Sbjct: 121 ASTLIRQVLDAVYYLHRM 138
>DAPK2_HUMAN (Q9UIK4) Death-associated protein kinase 2 (EC 2.7.11.1) (DAP| kinase 2) (DAP-kinase-related protein 1) (DRP-1) Length = 370 Score = 64.3 bits (155), Expect = 2e-10 Identities = 40/136 (29%), Positives = 69/136 (50%), Gaps = 8/136 (5%) Frame = +1 Query: 184 KTSNRSRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIE--------RGY 339 ++ N +++ D Y+ E+GSG F + K R + T A KFI+ RG Sbjct: 7 RSPNMEPFKQQKVEDFYDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGV 66 Query: 340 RIDENVFREIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDE 519 +E + RE+ R + H N+I +V T + +++E +GGELF+ + E+E Sbjct: 67 SREE-IEREVSILRQVLHHNVITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEE 125 Query: 520 ARYFFQQLVCGVSFCH 567 A F +Q++ GV++ H Sbjct: 126 ATSFIKQILDGVNYLH 141
>KPCL_RAT (Q64617) Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta)| (PKC-L) Length = 683 Score = 64.3 bits (155), Expect = 2e-10 Identities = 39/123 (31%), Positives = 65/123 (52%), Gaps = 5/123 (4%) Frame = +1 Query: 214 RSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRI-DENVFREIVNHRSL- 387 R G+D +E +R +G G+FG L R ++T EL A+K +++ + D++V + R L Sbjct: 349 RFGIDNFEFIRVLGKGSFGKVMLARIKETGELYAVKVLKKDVILQDDDVECTMTEKRILS 408 Query: 388 ---RHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVS 558 HP + + TP L VME+ GG+L I + RF E AR++ +++ + Sbjct: 409 LARNHPFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIISALM 468 Query: 559 FCH 567 F H Sbjct: 469 FLH 471
>KPCL_MOUSE (P23298) Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta)| (PKC-L) Length = 683 Score = 64.3 bits (155), Expect = 2e-10 Identities = 39/123 (31%), Positives = 65/123 (52%), Gaps = 5/123 (4%) Frame = +1 Query: 214 RSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRI-DENVFREIVNHRSL- 387 R G+D +E +R +G G+FG L R ++T EL A+K +++ + D++V + R L Sbjct: 349 RFGIDNFEFIRVLGKGSFGKVMLARIKETGELYAVKVLKKDVILQDDDVECTMTEKRILS 408 Query: 388 ---RHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVS 558 HP + + TP L VME+ GG+L I + RF E AR++ +++ + Sbjct: 409 LARNHPFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIISALM 468 Query: 559 FCH 567 F H Sbjct: 469 FLH 471
>KIN4_YEAST (Q01919) Serine/threonine-protein kinase KIN4 (EC 2.7.11.1)| Length = 800 Score = 63.9 bits (154), Expect = 3e-10 Identities = 41/131 (31%), Positives = 65/131 (49%), Gaps = 10/131 (7%) Frame = +1 Query: 205 ERERSGMDKYEPVREIGSGNFGVAKL-----MRNRDTRELVAMKFIERGYRIDE-----N 354 +R+ + Y +G G FG KL + + + VA+K I R + Sbjct: 37 QRKHATFGPYIIGSTLGEGEFGKVKLGWTKASSSNEVPKQVAIKLIRRDTIKKDADKEIK 96 Query: 355 VFREIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFF 534 ++REI + L HPNII +EV+ ++GIV+E+ +GGE ++ I R E A F Sbjct: 97 IYREINALKHLTHPNIIYLEEVLQNSKYIGIVLEFVSGGEFYKYIQRKRRLKESSACRLF 156 Query: 535 QQLVCGVSFCH 567 QL+ GV++ H Sbjct: 157 AQLISGVNYMH 167
>KAPCA_MOUSE (P05132) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 63.9 bits (154), Expect = 3e-10 Identities = 30/121 (24%), Positives = 68/121 (56%), Gaps = 4/121 (3%) Frame = +1 Query: 223 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHR----SLR 390 +D+++ ++ +G+G+FG L++++++ AMK +++ + +N + ++ Sbjct: 40 LDQFDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVN 99 Query: 391 HPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCHA 570 P +++ + ++L +VMEY AGGE+F + GRF E AR++ Q+V + H+ Sbjct: 100 FPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHS 159 Query: 571 M 573 + Sbjct: 160 L 160
>YP150_YEAST (Q12152) Putative serine/threonine-protein kinase YPL150W (EC| 2.7.11.1) Length = 901 Score = 63.9 bits (154), Expect = 3e-10 Identities = 35/121 (28%), Positives = 61/121 (50%) Frame = +1 Query: 211 ERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHRSLR 390 E + + Y+ +++IG G+FG L +R T V +K ++ D N+ RE+ HR Sbjct: 34 ELTEVGNYKILKQIGEGSFGKVYLALHRPTHRKVCLKTSDKN---DPNIVREVFYHRQFD 90 Query: 391 HPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCHA 570 P I + EV++T + + + +EY G EL++ + R E F Q+ V + H+ Sbjct: 91 FPYITKLYEVIVTESKVWMALEYCPGKELYDHLLSLRRISLLECGELFAQISGAVYYAHS 150 Query: 571 M 573 M Sbjct: 151 M 151
>KPC4_DROME (P83099) Putative protein kinase C, delta type homolog (EC| 2.7.11.13) Length = 643 Score = 63.9 bits (154), Expect = 3e-10 Identities = 36/120 (30%), Positives = 64/120 (53%), Gaps = 5/120 (4%) Frame = +1 Query: 223 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRI-DENVFREIVNHRSL---- 387 +D + + +G G+FG L RDT A+K +++ + D++V ++ + L Sbjct: 312 VDDFHFLAVLGKGSFGKVLLAELRDTTYYYAIKCLKKDVVLEDDDVDSTLIERKVLALGT 371 Query: 388 RHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCH 567 +HP + T +HL VMEY GG+L I ++GRF E+ AR++ +++ G+ F H Sbjct: 372 KHPYLCHLFCTFQTESHLFFVMEYLNGGDLMFHIQESGRFSEERARFYGAEIISGLKFLH 431
>AURKB_MOUSE (O70126) Serine/threonine-protein kinase 12 (EC 2.7.11.1)| (Aurora-related kinase 2) (Serine/threonine-protein kinase 5) (STK-1) (Aurora-B) Length = 345 Score = 63.5 bits (153), Expect = 4e-10 Identities = 34/130 (26%), Positives = 65/130 (50%), Gaps = 4/130 (3%) Frame = +1 Query: 190 SNRSRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGY----RIDENV 357 S S+ ++ +D +E R +G G FG L R + +R +VA+K + + ++ + Sbjct: 68 SQGSQNKQPFTIDNFEIGRPLGKGKFGNVYLAREKKSRFIVALKILFKSQIEKEGVEHQL 127 Query: 358 FREIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQ 537 REI L+HPNI++ + +++EYA GEL++ + + F E + Sbjct: 128 RREIEIQAHLKHPNILQLYNYFYDQQRIYLILEYAPRGELYKELQKSRTFDEQRTATIME 187 Query: 538 QLVCGVSFCH 567 +L +++CH Sbjct: 188 ELSDALTYCH 197
>AKT1_XENLA (Q98TY9) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (Protein kinase Akt-1) (Protein kinase B, alpha) (PKB alpha) (xAkt) Length = 481 Score = 63.5 bits (153), Expect = 4e-10 Identities = 38/130 (29%), Positives = 67/130 (51%), Gaps = 4/130 (3%) Frame = +1 Query: 193 NRSRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRI-DENVFREI 369 + S+ + + M+++E ++ +G G FG L++ + T AMK +++ + + V + Sbjct: 138 SHSKPKHKVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTL 197 Query: 370 VNHRSL---RHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQ 540 +R L RHP + K T L VMEYA GGELF + F ED AR++ + Sbjct: 198 TENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERIFSEDRARFYGAE 257 Query: 541 LVCGVSFCHA 570 +V + + H+ Sbjct: 258 IVSALDYLHS 267
>KAPCA_SHEEP (Q9MZD9) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 63.5 bits (153), Expect = 4e-10 Identities = 31/121 (25%), Positives = 66/121 (54%), Gaps = 4/121 (3%) Frame = +1 Query: 223 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHR----SLR 390 +D++E ++ +G+G+FG L+++ +T AMK +++ + +N + ++ Sbjct: 40 LDQFERIKTLGTGSFGRVMLVKHTETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVN 99 Query: 391 HPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCHA 570 P +++ + ++L +VMEY GGE+F + GRF E AR++ Q+V + H+ Sbjct: 100 FPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHS 159 Query: 571 M 573 + Sbjct: 160 L 160
>KAPCA_BOVIN (P00517) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 63.5 bits (153), Expect = 4e-10 Identities = 31/121 (25%), Positives = 66/121 (54%), Gaps = 4/121 (3%) Frame = +1 Query: 223 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHR----SLR 390 +D++E ++ +G+G+FG L+++ +T AMK +++ + +N + ++ Sbjct: 40 LDQFERIKTLGTGSFGRVMLVKHMETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVN 99 Query: 391 HPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCHA 570 P +++ + ++L +VMEY GGE+F + GRF E AR++ Q+V + H+ Sbjct: 100 FPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHS 159 Query: 571 M 573 + Sbjct: 160 L 160
>KPCL_HUMAN (P24723) Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta)| (PKC-L) Length = 682 Score = 63.5 bits (153), Expect = 4e-10 Identities = 38/123 (30%), Positives = 65/123 (52%), Gaps = 5/123 (4%) Frame = +1 Query: 214 RSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGY-RIDENVFREIVNHRSL- 387 R G+D +E +R +G G+FG L R ++T +L A+K +++ +D++V + R L Sbjct: 348 RLGIDNFEFIRVLGKGSFGKVMLARVKETGDLYAVKVLKKDVILLDDDVECTMTEKRILS 407 Query: 388 ---RHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVS 558 HP + + TP L VME+ GG+L I + RF E AR++ +++ + Sbjct: 408 LARNHPFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIISALM 467 Query: 559 FCH 567 F H Sbjct: 468 FLH 470
>KKK1_YEAST (P34244) Probable serine/threonine-protein kinase YKL101W (EC| 2.7.11.1) Length = 1518 Score = 63.5 bits (153), Expect = 4e-10 Identities = 44/176 (25%), Positives = 79/176 (44%), Gaps = 39/176 (22%) Frame = +1 Query: 160 SREIATHRKTSNRSRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIER-- 333 S+ +T + S+ + R + ++ + +G G+ G +L +N +T +L A+K + + Sbjct: 57 SQPDSTVSVATKSSKRKSRDTVGPWKLGKTLGKGSSGRVRLAKNMETGQLAAIKIVPKKK 116 Query: 334 ----------------GYRIDENVF---------------------REIVNHRSLRHPNI 402 + NV REIV + + H N+ Sbjct: 117 AFVHCSNNGTVPNSYSSSMVTSNVSSPSIASREHSNHSQTNPYGIEREIVIMKLISHTNV 176 Query: 403 IRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCHA 570 + EV + L +V+EY GGELF+ + G+ E EA ++F+Q+V GVS+CH+ Sbjct: 177 MALFEVWENKSELYLVLEYVDGGELFDYLVSKGKLPEREAIHYFKQIVEGVSYCHS 232
>STK6_HUMAN (O14965) Serine/threonine-protein kinase 6 (EC 2.7.11.1)| (Serine/threonine kinase 15) (Aurora/IPL1-related kinase 1) (Aurora-related kinase 1) (hARK1) (Aurora-A) (Breast-tumor-amplified kinase) Length = 403 Score = 63.5 bits (153), Expect = 4e-10 Identities = 37/148 (25%), Positives = 74/148 (50%), Gaps = 7/148 (4%) Frame = +1 Query: 148 SAPASR---EIATHRKTSNRSRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAM 318 SAP + E+A+ +K N ++ + ++ +E R +G G FG L R + ++ ++A+ Sbjct: 104 SAPENNPEEELASKQK--NEESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILAL 161 Query: 319 KFIERGYR----IDENVFREIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFER 486 K + + ++ + RE+ LRHPNI+R T + +++EYA G ++ Sbjct: 162 KVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRE 221 Query: 487 ICDAGRFHEDEARYFFQQLVCGVSFCHA 570 + +F E + +L +S+CH+ Sbjct: 222 LQKLSKFDEQRTATYITELANALSYCHS 249
>CHK1_DROME (O61661) Serine/threonine-protein kinase grp (EC 2.7.11.1) (Protein| grapes) (Chk1 homolog) Length = 512 Score = 63.5 bits (153), Expect = 4e-10 Identities = 40/120 (33%), Positives = 66/120 (55%), Gaps = 2/120 (1%) Frame = +1 Query: 214 RSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRID--ENVFREIVNHRSL 387 R ++ + + +G G +G KL+ NR T E VAMK ++ D +V +E+ + L Sbjct: 16 REFVEGWTLAQTLGEGAYGEVKLLINRQTGEAVAMKMVDLKKHPDAANSVRKEVCIQKML 75 Query: 388 RHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCH 567 + +I+RF + I +EYAAGGELF+RI + EA+ +F QL+ G+++ H Sbjct: 76 QDKHILRFFGKRSQGSVEYIFLEYAAGGELFDRIEPDVGMPQHEAQRYFTQLLSGLNYLH 135
>KIN1_YEAST (P13185) Protein kinase KIN1 (EC 2.7.11.1)| Length = 1064 Score = 63.2 bits (152), Expect = 5e-10 Identities = 46/176 (26%), Positives = 73/176 (41%), Gaps = 39/176 (22%) Frame = +1 Query: 160 SREIATHRKTSNRSRERERSGMDK---------YEPVREIGSGNFGVAKLMRNRDTRELV 312 SRE A T+++SR GM K +E V +G+G+ G KL ++R T E+ Sbjct: 87 SRENAPKPNTTSQSRVSSSQGMPKQFHRKSLGDWEFVETVGAGSMGKVKLAKHRYTNEVC 146 Query: 313 AMKFIERGYRI------------------------------DENVFREIVNHRSLRHPNI 402 A+K + R + D+ RE + L HP+I Sbjct: 147 AVKIVNRATKAFLHKEQMLPPPKNEQDVLERQKKLEKEISRDKRTIREASLGQILYHPHI 206 Query: 403 IRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCHA 570 R E+ H ++ EY +GG+L + I G E +AR F + + + + HA Sbjct: 207 CRLFEMCTLSNHFYMLFEYVSGGQLLDYIIQHGSIREHQARKFARGIASALIYLHA 262
>KS6A5_CHICK (Q5F3L1) Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1)| Length = 789 Score = 63.2 bits (152), Expect = 5e-10 Identities = 37/109 (33%), Positives = 57/109 (52%), Gaps = 1/109 (0%) Frame = +1 Query: 244 REIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHRSLR-HPNIIRFKEV 420 + +G G+F + + ++ T + A+K I + R++ N REI + HPN+++ EV Sbjct: 420 KPLGEGSFSICRKCLHKKTSQEYAVKIISK--RMEANTQREITALKLCEGHPNVVKLHEV 477 Query: 421 VLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCH 567 H +VME GGEL ERI F E EA + ++LV VS H Sbjct: 478 YHDQLHTFLVMELLKGGELLERIQKKQHFSETEASHIMRRLVSAVSHMH 526
>KAPCA_CRIGR (P25321) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 63.2 bits (152), Expect = 5e-10 Identities = 31/129 (24%), Positives = 69/129 (53%), Gaps = 4/129 (3%) Frame = +1 Query: 199 SRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNH 378 S + + +D ++ ++ +G+G+FG L+++++T AMK +++ + +N Sbjct: 32 SPSQNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNE 91 Query: 379 R----SLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLV 546 + ++ P +++ + ++L +VMEY GGE+F + GRF E AR++ Q+V Sbjct: 92 KRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIV 151 Query: 547 CGVSFCHAM 573 + H++ Sbjct: 152 LTFEYLHSL 160
>AKT1_RAT (P47196) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (Protein kinase B) (PKB) Length = 480 Score = 63.2 bits (152), Expect = 5e-10 Identities = 38/128 (29%), Positives = 66/128 (51%), Gaps = 4/128 (3%) Frame = +1 Query: 199 SRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRI-DENVFREIVN 375 ++ + R M+++E ++ +G G FG L++ + T AMK +++ + + V + Sbjct: 139 AKPKHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTE 198 Query: 376 HRSL---RHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLV 546 +R L RHP + K T L VMEYA GGELF + F ED AR++ ++V Sbjct: 199 NRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIV 258 Query: 547 CGVSFCHA 570 + + H+ Sbjct: 259 SALDYLHS 266
>AKT1_MOUSE (P31750) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (AKT1 kinase) (Protein kinase B) (PKB) (C-AKT) (Thymoma viral proto-oncogene) Length = 480 Score = 63.2 bits (152), Expect = 5e-10 Identities = 38/128 (29%), Positives = 66/128 (51%), Gaps = 4/128 (3%) Frame = +1 Query: 199 SRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRI-DENVFREIVN 375 ++ + R M+++E ++ +G G FG L++ + T AMK +++ + + V + Sbjct: 139 AKPKHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTE 198 Query: 376 HRSL---RHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLV 546 +R L RHP + K T L VMEYA GGELF + F ED AR++ ++V Sbjct: 199 NRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIV 258 Query: 547 CGVSFCHA 570 + + H+ Sbjct: 259 SALDYLHS 266
>AKT1_HUMAN (P31749) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (Protein kinase B) (PKB) (C-AKT) Length = 480 Score = 63.2 bits (152), Expect = 5e-10 Identities = 38/128 (29%), Positives = 66/128 (51%), Gaps = 4/128 (3%) Frame = +1 Query: 199 SRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRI-DENVFREIVN 375 ++ + R M+++E ++ +G G FG L++ + T AMK +++ + + V + Sbjct: 139 AKPKHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTE 198 Query: 376 HRSL---RHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLV 546 +R L RHP + K T L VMEYA GGELF + F ED AR++ ++V Sbjct: 199 NRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIV 258 Query: 547 CGVSFCHA 570 + + H+ Sbjct: 259 SALDYLHS 266
>SCK2_SCHPO (Q10364) Serine/threonine-protein kinase sck2 (EC 2.7.11.1)| Length = 646 Score = 63.2 bits (152), Expect = 5e-10 Identities = 36/123 (29%), Positives = 59/123 (47%), Gaps = 7/123 (5%) Frame = +1 Query: 220 GMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHRSLR--- 390 G D + P++ IG G FG L+R +DT + AMK + + + V R + Sbjct: 262 GPDDFVPLKLIGKGTFGQVYLVRKKDTERVYAMKVLSKKVIVRRKEVAHTVGERDILVQT 321 Query: 391 ----HPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVS 558 P I+ + TP L +V +Y AGGELF + + RF E+ A+++ +L+ + Sbjct: 322 SAADSPFIVALRFSFQTPKDLYLVTDYMAGGELFWHLQKSVRFPEERAKFYIAELLLALQ 381 Query: 559 FCH 567 H Sbjct: 382 ALH 384
>AKT_MLVAT (P31748) AKT kinase transforming protein (EC 2.7.11.1)| Length = 501 Score = 63.2 bits (152), Expect = 5e-10 Identities = 38/128 (29%), Positives = 66/128 (51%), Gaps = 4/128 (3%) Frame = +1 Query: 199 SRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRI-DENVFREIVN 375 ++ + R M+++E ++ +G G FG L++ + T AMK +++ + + V + Sbjct: 160 AKPKHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTE 219 Query: 376 HRSL---RHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLV 546 +R L RHP + K T L VMEYA GGELF + F ED AR++ ++V Sbjct: 220 NRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIV 279 Query: 547 CGVSFCHA 570 + + H+ Sbjct: 280 SALDYLHS 287
>KAPC_DROME (P12370) cAMP-dependent protein kinase catalytic subunit (EC| 2.7.11.11) (PKA C) Length = 352 Score = 63.2 bits (152), Expect = 5e-10 Identities = 29/128 (22%), Positives = 67/128 (52%), Gaps = 4/128 (3%) Frame = +1 Query: 196 RSRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVN 375 R + +D +E ++ +G+G+FG +++++ T++ AMK +++ + +N Sbjct: 33 RRNPTNTAALDDFERIKTLGTGSFGRVMIVQHKPTKDYYAMKILDKQKVVKLKQVEHTLN 92 Query: 376 HR----SLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQL 543 + +++ P ++ + ++L +V+EY GGE+F + GRF E +R++ Q+ Sbjct: 93 EKRILQAIQFPFLVSLRYHFKDNSNLYMVLEYVPGGEMFSHLRKVGRFSEPHSRFYAAQI 152 Query: 544 VCGVSFCH 567 V + H Sbjct: 153 VLAFEYLH 160
>CDK5_XENLA (P51166) Cell division protein kinase 5 (EC 2.7.11.22) (Neuronal| cyclin-dependent kinase 5) Length = 292 Score = 63.2 bits (152), Expect = 5e-10 Identities = 37/121 (30%), Positives = 65/121 (53%), Gaps = 5/121 (4%) Frame = +1 Query: 223 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFI---ERGYRIDENVFREIVNHRSLRH 393 M KYE + +IG G +G +NRDT E+VA+K + + + + REI + L+H Sbjct: 1 MQKYEKLEKIGEGTYGTVFKAKNRDTHEIVALKRVRLDDDDEGVPSSALREICLLKELKH 60 Query: 394 PNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDA--GRFHEDEARYFFQQLVCGVSFCH 567 NI+R +V+ + L +V E+ + ++ D+ G + + F QL+ G++FCH Sbjct: 61 KNIVRLHDVLHSDKKLTLVFEFC--DQDLKKYFDSCNGDLDPEIVKSFMYQLLKGLAFCH 118 Query: 568 A 570 + Sbjct: 119 S 119
>KCC2_SCHPO (O42844) Calcium/calmodulin-dependent protein kinase type II (EC| 2.7.11.17) (CAM kinase II) Length = 504 Score = 63.2 bits (152), Expect = 5e-10 Identities = 39/120 (32%), Positives = 63/120 (52%), Gaps = 4/120 (3%) Frame = +1 Query: 220 GMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRID----ENVFREIVNHRSL 387 G++KY+ + +G G F + D +E VA+K I R Y ++ + VF+E+ R + Sbjct: 61 GLEKYQLIENLGDGAFSQVYKAYSIDRKEHVAVKVI-RKYEMNKKQRQGVFKEVNIMRRV 119 Query: 388 RHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCH 567 +H N++ + V T +VME A GGELF +I + F E+ AR+ Q+ V H Sbjct: 120 KHKNVVNLFDFVETEDFYHLVMELAEGGELFHQIVNFTYFSENLARHIIIQVAEAVKHLH 179
>SCK1_SCHPO (P50530) Serine/threonine-protein kinase sck1 (EC 2.7.11.1)| Length = 696 Score = 62.8 bits (151), Expect = 7e-10 Identities = 37/128 (28%), Positives = 60/128 (46%), Gaps = 7/128 (5%) Frame = +1 Query: 205 ERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHRS 384 E R G + + +R IG G FG L+R DT + AMK I + + + + R+ Sbjct: 293 EHVRYGPEDFTALRLIGKGTFGQVYLVRKNDTNRIYAMKKISKKLIVRKKEVTHTLGERN 352 Query: 385 L-------RHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQL 543 + P I+ K T + L ++ +Y +GGELF + GRF E A+++ +L Sbjct: 353 ILVRTSLDESPFIVGLKFSFQTASDLYLITDYMSGGELFWHLQHEGRFPEQRAKFYIAEL 412 Query: 544 VCGVSFCH 567 V + H Sbjct: 413 VLALEHLH 420
>KAPCG_MACMU (O62846) cAMP-dependent protein kinase, gamma-catalytic subunit (EC| 2.7.11.11) (PKA C-gamma) (Fragment) Length = 208 Score = 62.8 bits (151), Expect = 7e-10 Identities = 31/120 (25%), Positives = 66/120 (55%), Gaps = 4/120 (3%) Frame = +1 Query: 226 DKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHR----SLRH 393 D++E ++ +G+G++G L+R+R+T AMK +++ + +N + ++ Sbjct: 40 DQFERLKTLGTGSYGRVMLVRHRETGNHYAMKILDKQKVVRLKQVEHTLNEKRILQAINF 99 Query: 394 PNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCHAM 573 P +++ + ++L +VMEY GGE+F + GRF E +A ++ Q+V + H++ Sbjct: 100 PFLVKLQFSFKDNSNLYLVMEYVPGGEMFSHLRRVGRFSEPQACFYAAQVVLAFQYLHSL 159
>AKT1_CAEEL (Q17941) Serine/threonine-protein kinase akt-1 (EC 2.7.11.1)| (Protein kinase B akt-1) (PKB akt-1) Length = 541 Score = 62.4 bits (150), Expect = 9e-10 Identities = 35/130 (26%), Positives = 69/130 (53%), Gaps = 4/130 (3%) Frame = +1 Query: 190 SNRSRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRID-ENVFRE 366 ++ + +R++ M+ ++ ++ +G G FG L + + T++L A+K +++ I E V Sbjct: 179 TSEAAKRDKITMEDFDFLKVLGKGTFGKVILCKEKRTQKLYAIKILKKDVIIAREEVAHT 238 Query: 367 IVNHRSL---RHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQ 537 + +R L +HP + K +L VM++A GGELF + G F E AR++ Sbjct: 239 LTENRVLQRCKHPFLTELKYSFQEQHYLCFVMQFANGGELFTHVRKCGTFSEPRARFYGA 298 Query: 538 QLVCGVSFCH 567 ++V + + H Sbjct: 299 EIVLALGYLH 308
>PHOT2_ARATH (P93025) Phototropin-2 (EC 2.7.11.1) (Defective in chloroplast| avoidance protein 1) (Non phototropic hypocotyl 1-like protein 1) (NPH1-like 1) (AtKin7) Length = 915 Score = 62.0 bits (149), Expect = 1e-09 Identities = 39/148 (26%), Positives = 73/148 (49%), Gaps = 8/148 (5%) Frame = +1 Query: 154 PASREIATHRKTSNRSRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIER 333 P ++E + + E G+ ++P++ +GSG+ G L+ + T EL AMK +E+ Sbjct: 551 PHNKESTSWKAIKKIQASGETVGLHHFKPIKPLGSGDTGSVHLVELKGTGELYAMKAMEK 610 Query: 334 GYRIDEN------VFREIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICD 495 ++ N + REI++ L HP + T TH+ ++ ++ GGELF + Sbjct: 611 TMMLNRNKAHRACIEREIIS--LLDHPFLPTLYASFQTSTHVCLITDFCPGGELFALLDR 668 Query: 496 AGR--FHEDEARYFFQQLVCGVSFCHAM 573 ED AR++ ++V G+ + H + Sbjct: 669 QPMKILTEDSARFYAAEVVIGLEYLHCL 696
>KDC2_DROME (P16912) Protein kinase DC2 (EC 2.7.11.1)| Length = 583 Score = 62.0 bits (149), Expect = 1e-09 Identities = 31/121 (25%), Positives = 63/121 (52%), Gaps = 4/121 (3%) Frame = +1 Query: 223 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHRSL----R 390 +D Y+ ++ +G+G FG L R+R + + AMK + I + N R++ R Sbjct: 271 LDDYQIIKTVGTGTFGRVCLCRDRISEKYCAMKILAMTEVIRLKQIEHVKNERNILREIR 330 Query: 391 HPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCHA 570 HP +I + ++L ++ +Y GGELF + +AG+F + ++ ++V + + H+ Sbjct: 331 HPFVISLEWSTKDDSNLYMIFDYVCGGELFTYLRNAGKFTSQTSNFYAAEIVSALEYLHS 390 Query: 571 M 573 + Sbjct: 391 L 391
>AKT2_RAT (P47197) RAC-beta serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta) Length = 481 Score = 62.0 bits (149), Expect = 1e-09 Identities = 37/128 (28%), Positives = 63/128 (49%), Gaps = 4/128 (3%) Frame = +1 Query: 199 SRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNH 378 S+ R + M+ ++ ++ +G G FG L+R + T AMK + + I ++ V Sbjct: 141 SKARAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTE 200 Query: 379 ----RSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLV 546 ++ RHP + K T L VMEYA GG+LF + F ED AR++ ++V Sbjct: 201 SRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGDLFFHLSRERVFTEDRARFYGAEIV 260 Query: 547 CGVSFCHA 570 + + H+ Sbjct: 261 SALEYLHS 268
>AKT2_MOUSE (Q60823) RAC-beta serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta) Length = 481 Score = 62.0 bits (149), Expect = 1e-09 Identities = 37/128 (28%), Positives = 63/128 (49%), Gaps = 4/128 (3%) Frame = +1 Query: 199 SRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNH 378 ++ R + M+ ++ ++ +G G FG L+R + T AMK + + I ++ V Sbjct: 141 NKARAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTE 200 Query: 379 ----RSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLV 546 ++ RHP + K T L VMEYA GGELF + F ED AR++ ++V Sbjct: 201 SRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEDRARFYGAEIV 260 Query: 547 CGVSFCHA 570 + + H+ Sbjct: 261 SALEYLHS 268
>AKT2_HUMAN (P31751) RAC-beta serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta) Length = 481 Score = 62.0 bits (149), Expect = 1e-09 Identities = 39/146 (26%), Positives = 69/146 (47%), Gaps = 4/146 (2%) Frame = +1 Query: 145 CSAPASREIATHRKTSNRSRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKF 324 C +P+ + + S+ R + M+ ++ ++ +G G FG L+R + T AMK Sbjct: 124 CGSPSDSSTTEEMEVAV-SKARAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKI 182 Query: 325 IERGYRIDENVFREIVNH----RSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERIC 492 + + I ++ V ++ RHP + K T L VMEYA GGELF + Sbjct: 183 LRKEVIIAKDEVAHTVTESRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLS 242 Query: 493 DAGRFHEDEARYFFQQLVCGVSFCHA 570 F E+ AR++ ++V + + H+ Sbjct: 243 RERVFTEERARFYGAEIVSALEYLHS 268
>CDK5_DROME (P48609) Cell division protein kinase 5 homolog (EC 2.7.11.22)| Length = 294 Score = 62.0 bits (149), Expect = 1e-09 Identities = 39/121 (32%), Positives = 64/121 (52%), Gaps = 5/121 (4%) Frame = +1 Query: 223 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFI---ERGYRIDENVFREIVNHRSLRH 393 M KY+ + +IG G +G RNRDT E+VA+K + E + + REI + L+H Sbjct: 1 MQKYDKMEKIGEGTYGTVFKGRNRDTMEIVALKRVRLDEDDEGVPSSALREICLLKELKH 60 Query: 394 PNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDA--GRFHEDEARYFFQQLVCGVSFCH 567 NI+R +V+ + L +V E+ + ++ D+ G R F QL+ G++FCH Sbjct: 61 KNIVRLIDVLHSDKKLTLVFEHC--DQDLKKYFDSLNGEIDMAVCRSFMLQLLRGLAFCH 118 Query: 568 A 570 + Sbjct: 119 S 119
>CDC2A_ANTMA (Q38772) Cell division control protein 2 homolog A (EC 2.7.11.22)| (EC 2.7.11.23) Length = 294 Score = 62.0 bits (149), Expect = 1e-09 Identities = 37/121 (30%), Positives = 65/121 (53%), Gaps = 5/121 (4%) Frame = +1 Query: 223 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFI---ERGYRIDENVFREIVNHRSLRH 393 M++YE V +IG G +GV R+R T E +A+K I + + REI + ++H Sbjct: 1 MEQYEKVEKIGEGTYGVVYKARDRVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQH 60 Query: 394 PNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDE--ARYFFQQLVCGVSFCH 567 NI+R ++VV + L +V EY +L + + F +D + F Q++ G+++CH Sbjct: 61 GNIVRLQDVVHSEKRLYLVFEY-LDLDLKKHMDSCPEFSQDPRLVKMFLYQILRGIAYCH 119 Query: 568 A 570 + Sbjct: 120 S 120
>DCAK2_HUMAN (Q8N568) Serine/threonine-protein kinase DCAMKL2 (EC 2.7.11.1)| (Doublecortin-like and CAM kinase-like 2) Length = 766 Score = 61.6 bits (148), Expect = 2e-09 Identities = 36/119 (30%), Positives = 61/119 (51%), Gaps = 2/119 (1%) Frame = +1 Query: 223 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDEN--VFREIVNHRSLRHP 396 ++KY+ + IG GNF V K +R T + A+K I++ + + E+ R ++HP Sbjct: 391 LEKYKIGKVIGDGNFAVVKECIDRSTGKEFALKIIDKAKCCGKEHLIENEVSILRRVKHP 450 Query: 397 NIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCHAM 573 NII E + T T L +VME GG+LF+ I + ++ E + L + + H + Sbjct: 451 NIIMLVEEMETATELFLVMELVKGGDLFDAITSSTKYTERDGSAMVYNLANALRYLHGL 509
>CDK3_HUMAN (Q00526) Cell division protein kinase 3 (EC 2.7.11.22)| Length = 305 Score = 61.6 bits (148), Expect = 2e-09 Identities = 40/122 (32%), Positives = 65/122 (53%), Gaps = 6/122 (4%) Frame = +1 Query: 223 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRID---ENVFREIVNHRSLRH 393 MD ++ V +IG G +GV +NR+T +LVA+K I ++ REI + L+H Sbjct: 1 MDMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKH 60 Query: 394 PNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHE---DEARYFFQQLVCGVSFC 564 PNI+R +VV L +V E+ + + ++ D+ E + + QL+ GVSFC Sbjct: 61 PNIVRLLDVVHNERKLYLVFEFLS--QDLKKYMDSTPGSELPLHLIKSYLFQLLQGVSFC 118 Query: 565 HA 570 H+ Sbjct: 119 HS 120
>YPK1_YEAST (P12688) Serine/threonine-protein kinase YPK1 (EC 2.7.11.1)| Length = 680 Score = 61.2 bits (147), Expect = 2e-09 Identities = 33/121 (27%), Positives = 63/121 (52%), Gaps = 4/121 (3%) Frame = +1 Query: 223 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHRSLRH--- 393 +D ++ ++ IG G+FG +R +DT+++ A+K I + Y + ++ + R++ Sbjct: 344 IDDFDLLKVIGKGSFGKVMQVRKKDTQKVYALKAIRKSYIVSKSEVTHTLAERTVLARVD 403 Query: 394 -PNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCHA 570 P I+ K +P L V+ + GGELF + GRF AR++ +L+C + H Sbjct: 404 CPFIVPLKFSFQSPEKLYFVLAFINGGELFYHLQKEGRFDLSRARFYTAELLCALDNLHK 463 Query: 571 M 573 + Sbjct: 464 L 464
>KAPCA_RAT (P27791) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 61.2 bits (147), Expect = 2e-09 Identities = 29/121 (23%), Positives = 66/121 (54%), Gaps = 4/121 (3%) Frame = +1 Query: 223 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHR----SLR 390 +D ++ ++ +G+G+FG L++++++ AMK +++ + +N + ++ Sbjct: 40 LDHFDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVN 99 Query: 391 HPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCHA 570 P +++ + ++L +VMEY GGE+F + GRF E AR++ Q+V + H+ Sbjct: 100 FPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHS 159 Query: 571 M 573 + Sbjct: 160 L 160
>KCC1_METAN (O14408) Calcium/calmodulin-dependent protein kinase (EC 2.7.11.17)| Length = 382 Score = 61.2 bits (147), Expect = 2e-09 Identities = 38/115 (33%), Positives = 65/115 (56%), Gaps = 2/115 (1%) Frame = +1 Query: 229 KYEPVREIGSGNFGVAKLMRNRDTRELVAMKFI-ERGYRIDEN-VFREIVNHRSLRHPNI 402 KY+ R +G+G +GV + + VA+K I ++ + +E V+ E+ + L HP+I Sbjct: 22 KYKFGRTLGAGTYGVVREADGPSGK--VAIKIILKKNVKGNEKMVYAELDMLQRLTHPHI 79 Query: 403 IRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCH 567 ++F + + IV + A GGELF+RICD G+F E +A +Q++ V + H Sbjct: 80 VKFVDWFESRDKFYIVTQLATGGELFDRICDQGKFTEVDASQTIRQIMTAVDYLH 134
>CDC21_MEDSA (P24923) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| (EC 2.7.11.23) (Fragment) Length = 291 Score = 60.8 bits (146), Expect = 3e-09 Identities = 40/118 (33%), Positives = 67/118 (56%), Gaps = 6/118 (5%) Frame = +1 Query: 235 EPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENV----FREIVNHRSLRHPNI 402 E V +IG G +GV R+R T E +A+K I R + DE V REI + ++H NI Sbjct: 2 ENVEKIGEGTYGVVYKARDRVTNETIALKKI-RLEQEDEGVPSTAIREISLLKEMQHRNI 60 Query: 403 IRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHED--EARYFFQQLVCGVSFCHA 570 +R ++VV + L +V EY +L + + + F +D + + F Q++CG+++CH+ Sbjct: 61 VRLQDVVHSDKRLYLVFEY-LDLDLKKHMDSSPEFIKDPRQVKMFLYQMLCGIAYCHS 117
>STK6_MOUSE (P97477) Serine/threonine-protein kinase 6 (EC 2.7.11.1)| (Aurora-family kinase 1) (Aurora/IPL1-related kinase 1) (Ipl1- and aurora-related kinase 1) (Aurora-A) (Serine/threonine-protein kinase Ayk1) Length = 395 Score = 60.8 bits (146), Expect = 3e-09 Identities = 34/142 (23%), Positives = 71/142 (50%), Gaps = 4/142 (2%) Frame = +1 Query: 157 ASREIATHRKTSNRSRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERG 336 + +E A+ +KT + + + ++ ++ R +G G FG L R R ++ ++A+K + + Sbjct: 101 SEKEQASLQKTEDTKKRQWT--LEDFDIGRPLGKGKFGNVYLARERQSKFILALKVLFKT 158 Query: 337 Y----RIDENVFREIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGR 504 ++ + RE+ LRHPNI+R T + +++EYA G ++ + + Sbjct: 159 QLEKANVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK 218 Query: 505 FHEDEARYFFQQLVCGVSFCHA 570 F E + +L +S+CH+ Sbjct: 219 FDEQRTATYITELANALSYCHS 240
>CDPK_DAUCA (P28582) Calcium-dependent protein kinase (EC 2.7.11.1) (CDPK)| Length = 532 Score = 60.8 bits (146), Expect = 3e-09 Identities = 46/148 (31%), Positives = 68/148 (45%), Gaps = 6/148 (4%) Frame = +1 Query: 148 SAPASREIATHRKTSNRSRERERSGM-DKYEPVREIGSGNFGVAKLMRNRDTRELVAMKF 324 + P+ + HR SN + + KY +E+G G FG + +L A K Sbjct: 52 TGPSLKPRQVHRPESNTILGKPFEDIRGKYTLGKELGRGQFGCVYQCTENSSGQLYACKS 111 Query: 325 IERGYRIDENVFREIVNH-RSLRH----PNIIRFKEVVLTPTHLGIVMEYAAGGELFERI 489 I + + +N +I + L+H PNI+ FK V + +VME AGGELF+RI Sbjct: 112 ILKRKLVSKNDKEDIKREIQILQHLSGQPNIVEFKGVFEDRQSVHLVMELCAGGELFDRI 171 Query: 490 CDAGRFHEDEARYFFQQLVCGVSFCHAM 573 G + E A +Q+V V CH M Sbjct: 172 IAQGHYSERAAATICRQIVNVVHVCHFM 199
>MAK_HUMAN (P20794) Serine/threonine-protein kinase MAK (EC 2.7.11.22) (Male| germ cell-associated kinase) Length = 623 Score = 60.8 bits (146), Expect = 3e-09 Identities = 37/118 (31%), Positives = 67/118 (56%), Gaps = 3/118 (2%) Frame = +1 Query: 223 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERG-YRIDENV-FREIVNHRSLRHP 396 M++Y +R++G G +G + ++ ++ ELVA+K ++R Y DE + RE+ + + L H Sbjct: 1 MNRYTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLNHA 60 Query: 397 NIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGR-FHEDEARYFFQQLVCGVSFCH 567 N+I+ KEV+ HL + EY L++ + D + F E R Q++ G++F H Sbjct: 61 NVIKLKEVIRENDHLYFIFEYMK-ENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIH 117
>MAK_RAT (P20793) Serine/threonine-protein kinase MAK (EC 2.7.11.22) (Male| germ cell-associated kinase) Length = 622 Score = 60.8 bits (146), Expect = 3e-09 Identities = 37/118 (31%), Positives = 67/118 (56%), Gaps = 3/118 (2%) Frame = +1 Query: 223 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERG-YRIDENV-FREIVNHRSLRHP 396 M++Y +R++G G +G + ++ ++ ELVA+K ++R Y DE + RE+ + + L H Sbjct: 1 MNRYTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLNHA 60 Query: 397 NIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGR-FHEDEARYFFQQLVCGVSFCH 567 N+I+ KEV+ HL + EY L++ + D + F E R Q++ G++F H Sbjct: 61 NVIKLKEVIRENDHLYFIFEYMK-ENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIH 117
>ICK_HUMAN (Q9UPZ9) Serine/threonine-protein kinase ICK (EC 2.7.11.22)| (Intestinal cell kinase) (hICK) (MAK-related kinase) (MRK) (Laryngeal cancer kinase 2) (LCK2) Length = 632 Score = 60.8 bits (146), Expect = 3e-09 Identities = 35/118 (29%), Positives = 65/118 (55%), Gaps = 3/118 (2%) Frame = +1 Query: 223 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENV--FREIVNHRSLRHP 396 M++Y +R++G G +G L R+ ++ EL+A+K ++R + E RE+ + + L H Sbjct: 1 MNRYTTIRQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNLREVKSLKKLNHA 60 Query: 397 NIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGR-FHEDEARYFFQQLVCGVSFCH 567 N+++ KEV+ HL + EY L++ I + + F E R Q++ G++F H Sbjct: 61 NVVKLKEVIRENDHLYFIFEYMK-ENLYQLIKERNKLFPESAIRNIMYQILQGLAFIH 117
>NEK1_MOUSE (P51954) Serine/threonine-protein kinase Nek1 (EC 2.7.11.1)| (NimA-related protein kinase 1) Length = 1203 Score = 60.5 bits (145), Expect = 3e-09 Identities = 38/120 (31%), Positives = 63/120 (52%), Gaps = 5/120 (4%) Frame = +1 Query: 223 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRID---ENVFREIVNHRSLRH 393 M+KY +++IG G+FG A L+++ + +K I D + RE+ +++H Sbjct: 1 MEKYVRLQKIGEGSFGKAVLVKSTEDGRHYVIKEINISRMSDKERQESRREVAVLANMKH 60 Query: 394 PNIIRFKEVVLTPTHLGIVMEYAAGGELFERI--CDAGRFHEDEARYFFQQLVCGVSFCH 567 PNI+++KE L IVM+Y GG+LF+RI F ED+ +F Q+ + H Sbjct: 61 PNIVQYKESFEENGSLYIVMDYCEGGDLFKRINAQKGALFQEDQILDWFVQICLALKHVH 120
>CHK1_SCHPO (P34208) Serine/threonine-protein kinase chk1 (EC 2.7.11.1)| (Checkpoint kinase 1) Length = 496 Score = 60.5 bits (145), Expect = 3e-09 Identities = 39/122 (31%), Positives = 62/122 (50%), Gaps = 9/122 (7%) Frame = +1 Query: 232 YEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRID--------ENVFREIVNHRSL 387 Y REIG+G F +L + D ++ A+KF+ + + + EI H+ Sbjct: 10 YHIGREIGTGAFASVRLCYD-DNAKIYAVKFVNKKHATSCMNAGVWARRMASEIQLHKLC 68 Query: 388 R-HPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFC 564 H NII F P +V+E+A GG+LF++I ED A+++F QL+ G+SF Sbjct: 69 NGHKNIIHFYNTAENPQWRWVVLEFAQGGDLFDKIEPDVGIDEDVAQFYFAQLMEGISFM 128 Query: 565 HA 570 H+ Sbjct: 129 HS 130
>CDK5_MOUSE (P49615) Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein| kinase II catalytic subunit) (TPKII catalytic subunit) (Serine/threonine-protein kinase PSSALRE) (CRK6) Length = 292 Score = 60.5 bits (145), Expect = 3e-09 Identities = 36/121 (29%), Positives = 64/121 (52%), Gaps = 5/121 (4%) Frame = +1 Query: 223 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFI---ERGYRIDENVFREIVNHRSLRH 393 M KYE + +IG G +G +NR+T E+VA+K + + + + REI + L+H Sbjct: 1 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH 60 Query: 394 PNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDA--GRFHEDEARYFFQQLVCGVSFCH 567 NI+R +V+ + L +V E+ + ++ D+ G + + F QL+ G+ FCH Sbjct: 61 KNIVRLHDVLHSDKKLTLVFEFC--DQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCH 118 Query: 568 A 570 + Sbjct: 119 S 119
>CDK5_HUMAN (Q00535) Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein| kinase II catalytic subunit) (TPKII catalytic subunit) (Serine/threonine-protein kinase PSSALRE) Length = 292 Score = 60.5 bits (145), Expect = 3e-09 Identities = 36/121 (29%), Positives = 64/121 (52%), Gaps = 5/121 (4%) Frame = +1 Query: 223 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFI---ERGYRIDENVFREIVNHRSLRH 393 M KYE + +IG G +G +NR+T E+VA+K + + + + REI + L+H Sbjct: 1 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH 60 Query: 394 PNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDA--GRFHEDEARYFFQQLVCGVSFCH 567 NI+R +V+ + L +V E+ + ++ D+ G + + F QL+ G+ FCH Sbjct: 61 KNIVRLHDVLHSDKKLTLVFEFC--DQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCH 118 Query: 568 A 570 + Sbjct: 119 S 119
>CDK5_BOVIN (Q02399) Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein| kinase II catalytic subunit) (TPKII catalytic subunit) (Proline-directed protein kinase 33 kDa subunit) (PDPK) Length = 292 Score = 60.5 bits (145), Expect = 3e-09 Identities = 36/121 (29%), Positives = 64/121 (52%), Gaps = 5/121 (4%) Frame = +1 Query: 223 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFI---ERGYRIDENVFREIVNHRSLRH 393 M KYE + +IG G +G +NR+T E+VA+K + + + + REI + L+H Sbjct: 1 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH 60 Query: 394 PNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDA--GRFHEDEARYFFQQLVCGVSFCH 567 NI+R +V+ + L +V E+ + ++ D+ G + + F QL+ G+ FCH Sbjct: 61 KNIVRLHDVLHSDKKLTLVFEFC--DQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCH 118 Query: 568 A 570 + Sbjct: 119 S 119
>ICK_RAT (Q62726) Serine/threonine-protein kinase ICK (EC 2.7.11.22)| (Intestinal cell kinase) (MAK-related kinase) (MRK) Length = 629 Score = 60.1 bits (144), Expect = 4e-09 Identities = 35/118 (29%), Positives = 65/118 (55%), Gaps = 3/118 (2%) Frame = +1 Query: 223 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVF--REIVNHRSLRHP 396 M++Y ++++G G +G L R+ ++ EL+A+K ++R + E RE+ + + L H Sbjct: 1 MNRYTTIKQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNLREVKSLKKLNHA 60 Query: 397 NIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGR-FHEDEARYFFQQLVCGVSFCH 567 NI++ KEV+ HL + EY L++ I + + F E R Q++ G++F H Sbjct: 61 NIVKLKEVIRENDHLYFIFEYMK-ENLYQLIKERNKLFPESAIRNIMYQILQGLAFIH 117
>ICK_MOUSE (Q9JKV2) Serine/threonine-protein kinase ICK (EC 2.7.11.22)| (Intestinal cell kinase) (mICK) (MAK-related kinase) (MRK) Length = 629 Score = 60.1 bits (144), Expect = 4e-09 Identities = 35/118 (29%), Positives = 65/118 (55%), Gaps = 3/118 (2%) Frame = +1 Query: 223 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVF--REIVNHRSLRHP 396 M++Y ++++G G +G L R+ ++ EL+A+K ++R + E RE+ + + L H Sbjct: 1 MNRYTTIKQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNLREVKSLKKLNHA 60 Query: 397 NIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGR-FHEDEARYFFQQLVCGVSFCH 567 NI++ KEV+ HL + EY L++ I + + F E R Q++ G++F H Sbjct: 61 NIVKLKEVIRENDHLYFIFEYMK-ENLYQLIKERNKLFPESAIRNIMYQILQGLAFIH 117
>DCAK2_MOUSE (Q6PGN3) Serine/threonine-protein kinase DCAMKL2 (EC 2.7.11.1)| (Doublecortin-like and CAM kinase-like 2) Length = 756 Score = 60.1 bits (144), Expect = 4e-09 Identities = 36/119 (30%), Positives = 61/119 (51%), Gaps = 2/119 (1%) Frame = +1 Query: 223 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDEN--VFREIVNHRSLRHP 396 ++KY + IG GNF V K +R T + A+K I++ + + E+ R ++HP Sbjct: 390 LEKYRIGKVIGDGNFAVVKECVDRYTGKEFALKIIDKAKCCGKEHLIENEVSILRRVKHP 449 Query: 397 NIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCHAM 573 NII E + T T L +VME GG+LF+ I + ++ E + L + + H++ Sbjct: 450 NIIMLVEEMETATDLFLVMELVKGGDLFDAITSSTKYTERDGSAMVYNLANALRYLHSL 508
>MAK_MOUSE (Q04859) Serine/threonine-protein kinase MAK (EC 2.7.11.22) (Male| germ cell-associated kinase) (Protein kinase RCK) Length = 622 Score = 60.1 bits (144), Expect = 4e-09 Identities = 37/118 (31%), Positives = 67/118 (56%), Gaps = 3/118 (2%) Frame = +1 Query: 223 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERG-YRIDENV-FREIVNHRSLRHP 396 M++Y ++++G G +G + ++ ++ ELVA+K ++R Y DE + RE+ + + L H Sbjct: 1 MNRYTTMKQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLNHA 60 Query: 397 NIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGR-FHEDEARYFFQQLVCGVSFCH 567 N+I+ KEV+ HL V EY L++ + D + F E R Q++ G++F H Sbjct: 61 NVIKLKEVIRENDHLYFVFEYMK-ENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIH 117
>AKT2B_XENLA (Q6IP76) RAC-beta serine/threonine-protein kinase-B (EC 2.7.11.1)| (RAC-PK-beta-B) (Protein kinase Akt-2-B) (Protein kinase B, beta-B) (PKB beta-B) Length = 485 Score = 60.1 bits (144), Expect = 4e-09 Identities = 39/128 (30%), Positives = 63/128 (49%), Gaps = 4/128 (3%) Frame = +1 Query: 199 SRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRI-DENVFREIVN 375 S+ R + M+ ++ ++ +G G FG L+R + T AMK + + I + V + Sbjct: 145 SKGRPKVTMNDFDYLKLLGKGTFGKVILVREKATGLYYAMKILRKEVIIAKDEVAHTLTE 204 Query: 376 HRSL---RHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLV 546 R L +HP + K T L VMEYA GGELF + F ED AR++ ++V Sbjct: 205 SRVLQNTKHPFLTGLKYAFQTSDRLCFVMEYANGGELFFHLSRERVFTEDRARFYGAEIV 264 Query: 547 CGVSFCHA 570 + + H+ Sbjct: 265 SALEYLHS 272
>CDC2_CHERU (P93101) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) Length = 294 Score = 60.1 bits (144), Expect = 4e-09 Identities = 37/121 (30%), Positives = 65/121 (53%), Gaps = 5/121 (4%) Frame = +1 Query: 223 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFI---ERGYRIDENVFREIVNHRSLRH 393 MD+YE V +IG G +GV R++ T E +A+K I + + REI + ++H Sbjct: 1 MDQYEKVEKIGEGTYGVVYKARDKVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQH 60 Query: 394 PNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDE--ARYFFQQLVCGVSFCH 567 NI+R ++VV + L +V EY +L + + F +D + F Q++ G+++CH Sbjct: 61 GNIVRLQDVVHSEKRLYLVFEY-LDLDLKKHMDSCPDFAKDPRMIKRFLYQILRGIAYCH 119 Query: 568 A 570 + Sbjct: 120 S 120
>CDPK1_ARATH (Q06850) Calcium-dependent protein kinase, isoform AK1 (EC| 2.7.11.1) (CDPK) Length = 610 Score = 60.1 bits (144), Expect = 4e-09 Identities = 47/147 (31%), Positives = 66/147 (44%), Gaps = 5/147 (3%) Frame = +1 Query: 148 SAPASREIATHRKTSNRSRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFI 327 SA E RKT N + Y R++G G FG L + T + A K I Sbjct: 130 SAGLRTESVLQRKTENFK--------EFYSLGRKLGQGQFGTTFLCVEKTTGKEFACKSI 181 Query: 328 ERGYRID----ENVFREI-VNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERIC 492 + + E+V REI + H HPN+I K + +VME AGGELF+RI Sbjct: 182 AKRKLLTDEDVEDVRREIQIMHHLAGHPNVISIKGAYEDVVAVHLVMECCAGGELFDRII 241 Query: 493 DAGRFHEDEARYFFQQLVCGVSFCHAM 573 G + E +A + +V V CH++ Sbjct: 242 QRGHYTERKAAELTRTIVGVVEACHSL 268
>AKT2A_XENLA (Q7ZX15) RAC-beta serine/threonine-protein kinase-A (EC 2.7.11.1)| (RAC-PK-beta-A) (Protein kinase Akt-2-A) (Protein kinase B, beta-A) (PKB beta-A) Length = 486 Score = 59.7 bits (143), Expect = 6e-09 Identities = 38/128 (29%), Positives = 62/128 (48%), Gaps = 4/128 (3%) Frame = +1 Query: 199 SRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRI-DENVFREIVN 375 S+ + M+ ++ ++ +G G FG L+R + T AMK + + I + V + Sbjct: 146 SKGHPKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTLTE 205 Query: 376 HRSL---RHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLV 546 R L +HP + K T L VMEYA GGELF + F ED AR++ ++V Sbjct: 206 SRVLQNTKHPFLTALKYAFQTSDRLCFVMEYANGGELFFHLSRERVFTEDRARFYGAEIV 265 Query: 547 CGVSFCHA 570 + + H+ Sbjct: 266 SALEYLHS 273
>CDPK4_PLAF7 (Q8IBS5) Calcium-dependent protein kinase 4 (EC 2.7.11.1)| Length = 527 Score = 59.7 bits (143), Expect = 6e-09 Identities = 34/118 (28%), Positives = 65/118 (55%), Gaps = 4/118 (3%) Frame = +1 Query: 226 DKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGY---RID-ENVFREIVNHRSLRH 393 ++Y+ ++ +G G+FG L R++ T A+K I + + + D E++ RE+ + L H Sbjct: 67 EQYKGIKILGKGSFGEVILSRDKHTGHEYAIKVISKKHVKRKTDKESLLREVELLKMLDH 126 Query: 394 PNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCH 567 NI++ E + +V + GGELF+ I RF+E +A +Q++ G+++ H Sbjct: 127 INIMKLYEFFEDNNYYYLVSDVYTGGELFDEIISRKRFYEIDAARIIKQILSGITYMH 184
>YPK2_YEAST (P18961) Serine/threonine-protein kinase YPK2/YKR2 (EC 2.7.11.1)| Length = 677 Score = 59.3 bits (142), Expect = 8e-09 Identities = 31/121 (25%), Positives = 63/121 (52%), Gaps = 4/121 (3%) Frame = +1 Query: 223 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHRSLRH--- 393 +D ++ ++ IG G+FG +R +DT+++ A+K + + Y + + + R++ Sbjct: 341 IDDFDLLKVIGKGSFGKVMQVRKKDTQKIYALKALRKAYIVSKCEVTHTLAERTVLARVD 400 Query: 394 -PNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCHA 570 P I+ K +P L +V+ + GGELF + GRF +R++ +L+C + H Sbjct: 401 CPFIVPLKFSFQSPEKLYLVLAFINGGELFYHLQHEGRFSLARSRFYIAELLCALDSLHK 460 Query: 571 M 573 + Sbjct: 461 L 461
>CDKL1_HUMAN (Q00532) Cyclin-dependent kinase-like 1 (EC 2.7.11.22)| (Serine/threonine-protein kinase KKIALRE) (Protein kinase p42 KKIALRE) Length = 357 Score = 59.3 bits (142), Expect = 8e-09 Identities = 41/118 (34%), Positives = 59/118 (50%), Gaps = 3/118 (2%) Frame = +1 Query: 223 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAM-KFIER--GYRIDENVFREIVNHRSLRH 393 M+KYE + +IG G++GV RNRDT ++VA+ KF+E I + REI + L+H Sbjct: 1 MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQLKH 60 Query: 394 PNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCH 567 PN++ EV L +V EY L E E + Q + V+FCH Sbjct: 61 PNLVNLLEVFRRKRRLHLVFEYCDHTVLHELDRYQRGVPEHLVKSITWQTLQAVNFCH 118
>CDPK3_ORYSA (P53684) Calcium-dependent protein kinase, isoform 11 (EC 2.7.11.1)| (CDPK 11) Length = 542 Score = 59.3 bits (142), Expect = 8e-09 Identities = 40/115 (34%), Positives = 59/115 (51%), Gaps = 5/115 (4%) Frame = +1 Query: 244 REIGSGNFGVAKLMRNRDTRELVAMKFIERGYRID----ENVFREI-VNHRSLRHPNIIR 408 R++G G FG L +T A K I + I E+V REI + H H N++ Sbjct: 83 RKLGQGQFGTTYLCTEINTGCEYACKTIPKRKLITKEDVEDVRREIQIMHHLSGHKNVVA 142 Query: 409 FKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCHAM 573 K+V + IVME AGGELF+RI + G + E +A + +V V+ CH++ Sbjct: 143 IKDVYEDGQAVHIVMELCAGGELFDRIQEKGHYSERKAAELIRIIVSIVAMCHSL 197
>CDK2_XENLA (P23437) Cell division protein kinase 2 (EC 2.7.11.22) (CDC2| homolog Eg1 protein kinase) Length = 297 Score = 59.3 bits (142), Expect = 8e-09 Identities = 36/122 (29%), Positives = 61/122 (50%), Gaps = 6/122 (4%) Frame = +1 Query: 223 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYR---IDENVFREIVNHRSLRH 393 M+ ++ V +IG G +GV RNR+T E+VA+K I + REI + L H Sbjct: 1 MENFQKVEKIGEGTYGVVYKARNRETGEIVALKKIRLDTETEGVPSTAIREISLLKELNH 60 Query: 394 PNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDE---ARYFFQQLVCGVSFC 564 PNI++ +V+ T L +V E+ + ++ D + + QL+ G++FC Sbjct: 61 PNIVKLLDVIHTENKLYLVFEFL--NQDLKKFMDGSNISGISLALVKSYLFQLLQGLAFC 118 Query: 565 HA 570 H+ Sbjct: 119 HS 120
>CDKL1_BRARE (Q6AXJ9) Cyclin-dependent kinase-like 1 (EC 2.7.11.22)| Length = 350 Score = 59.3 bits (142), Expect = 8e-09 Identities = 40/118 (33%), Positives = 59/118 (50%), Gaps = 3/118 (2%) Frame = +1 Query: 223 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAM-KFIER--GYRIDENVFREIVNHRSLRH 393 M+KYE + +IG G++GV RN+DT ++VA+ KF+E I + REI + L+H Sbjct: 1 MEKYEKISKIGEGSYGVVFKCRNKDTGQIVAIKKFVESEDDPIIKKIALREIRMLKQLKH 60 Query: 394 PNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCH 567 PN++ EV L +V EY L E E + Q + V+FCH Sbjct: 61 PNLVNLMEVFRRKRKLHLVFEYCDHTVLNELDRYPRGVPEHMVKSIIWQTLQAVNFCH 118
>ATG1_NEUCR (Q7RX99) Serine/threonine-protein kinase atg-1 (EC 2.7.11.1)| (Autophagy-related protein 1) Length = 932 Score = 59.3 bits (142), Expect = 8e-09 Identities = 33/104 (31%), Positives = 59/104 (56%), Gaps = 3/104 (2%) Frame = +1 Query: 175 THRKTSNRSRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGY---RI 345 T +S+R ++ + + +EIG G+F L R++ T LVA+K +E ++ Sbjct: 5 TSASSSSRRTKQNYDAIGSFVIDQEIGKGSFAKVYLGRHKVTGALVAVKSVELARLNKKL 64 Query: 346 DENVFREIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGEL 477 EN++ EI ++LRHP+I+ + V + TH+ ++MEY G+L Sbjct: 65 KENLYGEIQILKTLRHPHIVALHDCVESSTHINLIMEYCELGDL 108
>KCC1_EMENI (Q00771) Calcium/calmodulin-dependent protein kinase (EC 2.7.11.17)| (CMPK) Length = 414 Score = 59.3 bits (142), Expect = 8e-09 Identities = 41/131 (31%), Positives = 71/131 (54%), Gaps = 3/131 (2%) Frame = +1 Query: 184 KTSNRSRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRE-LVAMKFI-ERGYRIDEN- 354 K S + E+ + ++ R +G+G +G+ +R D VA+K I +R R +E Sbjct: 9 KLSGQPESYEKKSLYRFG--RTLGAGTYGI---VREADCSSGKVAVKIILKRNVRGNERM 63 Query: 355 VFREIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFF 534 V+ E+ + L HP+I+ F + + IV + A GGELF+RIC+ G+F E +A Sbjct: 64 VYDELDLLQKLNHPHIVHFVDWFESKDKFYIVTQLATGGELFDRICEYGKFTEKDASQTI 123 Query: 535 QQLVCGVSFCH 567 +Q++ V++ H Sbjct: 124 RQVLDAVNYLH 134
>CDKL1_MOUSE (Q8CEQ0) Cyclin-dependent kinase-like 1 (EC 2.7.11.22)| Length = 352 Score = 59.3 bits (142), Expect = 8e-09 Identities = 41/118 (34%), Positives = 59/118 (50%), Gaps = 3/118 (2%) Frame = +1 Query: 223 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMK-FIER--GYRIDENVFREIVNHRSLRH 393 M+KYE + +IG G++GV RNRDT ++VA+K F+E I + REI + L+H Sbjct: 1 MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKRFLETEDDPVIKKIALREIRMLKQLKH 60 Query: 394 PNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCH 567 PN++ EV L +V EY L E E + Q + V+FCH Sbjct: 61 PNLVNLLEVFRRKRRLHLVFEYCDHTVLHELDRYQRGVPEPLVKNITWQTLQAVNFCH 118
>CDPK_SOYBN (P28583) Calcium-dependent protein kinase SK5 (EC 2.7.11.1) (CDPK)| Length = 508 Score = 59.3 bits (142), Expect = 8e-09 Identities = 39/128 (30%), Positives = 63/128 (49%), Gaps = 5/128 (3%) Frame = +1 Query: 205 ERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRID----ENVFREI- 369 +R ++ + YE R++G G FG R + A K I + + E+V+REI Sbjct: 25 QRTQNIREVYEVGRKLGQGQFGTTFECTRRASGGKFACKSIPKRKLLCKEDYEDVWREIQ 84 Query: 370 VNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVC 549 + H H N++R + T + +VME GGELF+RI G + E +A + +V Sbjct: 85 IMHHLSEHANVVRIEGTYEDSTAVHLVMELCEGGELFDRIVQKGHYSERQAARLIKTIVE 144 Query: 550 GVSFCHAM 573 V CH++ Sbjct: 145 VVEACHSL 152
>CDK3_MOUSE (Q80YP0) Truncated cell division protein kinase 3 homolog| Length = 186 Score = 59.3 bits (142), Expect = 8e-09 Identities = 41/122 (33%), Positives = 62/122 (50%), Gaps = 6/122 (4%) Frame = +1 Query: 223 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIE---RGYRIDENVFREIVNHRSLRH 393 MD ++ V +IG G +GV RN+ T +LVA+K I + REI + L+H Sbjct: 1 MDVFQKVEKIGEGTYGVVYKARNKVTGQLVALKKIRLDLEAEGVPSTAVREISLLKELKH 60 Query: 394 PNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHE---DEARYFFQQLVCGVSFC 564 PNII+ +VV L +V E+ + +R D+ E + + QL+ GVSFC Sbjct: 61 PNIIKLLDVVHREKKLYMVFEFLT--QDLKRHMDSSPTSELPLPVVKSYLAQLLEGVSFC 118 Query: 565 HA 570 H+ Sbjct: 119 HS 120
>CRK_DAUCA (P53681) CDPK-related protein kinase (EC 2.7.11.1) (PK421)| Length = 602 Score = 58.9 bits (141), Expect = 1e-08 Identities = 41/122 (33%), Positives = 66/122 (54%), Gaps = 9/122 (7%) Frame = +1 Query: 229 KYEPVREIGSGNFGV---AKLMRNRDTRELVAMKFIERGYRID----ENVFREIVNHRSL 387 K+E E+G G+FG AK + + VA+K I + E+V RE+ R+L Sbjct: 147 KFEVGEEVGRGHFGYTCRAKFKKGEFKGQDVAVKVIPKAKMTTAIAIEDVRREVKILRAL 206 Query: 388 R-HPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICD-AGRFHEDEARYFFQQLVCGVSF 561 H N+++F + T++ +VME GGEL +RI G++ ED+A+ Q++ V+F Sbjct: 207 TGHNNLVQFYDAFEDHTNVYVVMELCEGGELLDRILSRGGKYTEDDAKAVMIQILNVVAF 266 Query: 562 CH 567 CH Sbjct: 267 CH 268
>AURKB_HUMAN (Q96GD4) Serine/threonine-protein kinase 12 (EC 2.7.11.1) (Aurora-| and Ipl1-like midbody-associated protein 1) (AIM-1) (Aurora/IPL1-related kinase 2) (Aurora-related kinase 2) (STK-1) (Aurora-B) Length = 344 Score = 58.9 bits (141), Expect = 1e-08 Identities = 32/119 (26%), Positives = 57/119 (47%), Gaps = 4/119 (3%) Frame = +1 Query: 223 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGY----RIDENVFREIVNHRSLR 390 +D +E R +G G FG L R + + +VA+K + + ++ + REI L Sbjct: 74 IDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLH 133 Query: 391 HPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCH 567 HPNI+R + +++EYA GEL++ + + F E ++L + +CH Sbjct: 134 HPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCH 192
>PEF1_SCHPO (O74456) Serine/threonine-protein kinase pef1 (EC 2.7.11.22)| (Cyclin-dependent kinase pef1) (PHO85 homolog) Length = 288 Score = 58.9 bits (141), Expect = 1e-08 Identities = 39/120 (32%), Positives = 60/120 (50%), Gaps = 8/120 (6%) Frame = +1 Query: 232 YEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDEN------VFREIVNHRSLRH 393 Y+ + ++G G + +NR T E+VA+K I RID + REI + LRH Sbjct: 3 YQRLEKLGEGTYAHVYKGQNRVTGEIVALKVI----RIDADEGTPSTAIREISLMKELRH 58 Query: 394 PNIIRFKEVVLTPTHLGIVMEYAAGG--ELFERICDAGRFHEDEARYFFQQLVCGVSFCH 567 PNI+ +V+ T L +V EY + + + G + + F QQL+ G+SFCH Sbjct: 59 PNIMSLSDVLQTENKLMLVFEYMEKDLKKYMDTYGNQGALPPSQVKNFTQQLLKGISFCH 118
>KK31_SCHPO (Q9HFF4) Probable serine/threonine-protein kinase C110.01 (EC| 2.7.11.1) Length = 1023 Score = 58.9 bits (141), Expect = 1e-08 Identities = 38/121 (31%), Positives = 60/121 (49%), Gaps = 12/121 (9%) Frame = +1 Query: 244 REIGSGNFGVAKL---------MRNRDTRELVAMKFIERGYRIDEN-VFREIVNHRSL-- 387 R IG+G FG KL +R T ++V + + + RE+ + L Sbjct: 496 RTIGTGEFGKVKLGWPLPKANSTIHRSTPQVVIKIVLSTKQNCQTSRLMREVAILKGLGN 555 Query: 388 RHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCH 567 HP+I+++ + V T H GIV++Y GGELF+ I R + A F QL+ GV++ H Sbjct: 556 NHPHIVKYLDFVKTKHHFGIVLDYVNGGELFDYILARRRLEDSVACRLFAQLISGVAYLH 615 Query: 568 A 570 + Sbjct: 616 S 616
>CDKL1_RAT (Q66HE7) Cyclin-dependent kinase-like 1 (EC 2.7.11.22)| Length = 352 Score = 58.9 bits (141), Expect = 1e-08 Identities = 41/118 (34%), Positives = 59/118 (50%), Gaps = 3/118 (2%) Frame = +1 Query: 223 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMK-FIER--GYRIDENVFREIVNHRSLRH 393 M+KYE + +IG G++GV RNRDT ++VA+K F+E I + REI + L+H Sbjct: 1 MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKRFLETEDDPVIKKIALREIRMLKQLKH 60 Query: 394 PNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCH 567 PN++ EV L +V EY L E E + Q + V+FCH Sbjct: 61 PNLVSLLEVFRRKRRLHLVFEYCHHTVLHELDRYQRGVPEPLVKNITWQTLQAVNFCH 118
>AKT1_DROME (Q8INB9) RAC serine/threonine-protein kinase (EC 2.7.11.1)| (DRAC-PK) (Akt) (Dakt1) (Protein kinase B) (PKB) Length = 611 Score = 58.9 bits (141), Expect = 1e-08 Identities = 36/141 (25%), Positives = 68/141 (48%), Gaps = 4/141 (2%) Frame = +1 Query: 160 SREIATHRKTSNRSRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGY 339 S + + T N S ++ + ++ +E ++ +G G FG L R + T +L A+K +++ Sbjct: 243 SEQFSVQGTTCNSSGVKKVT-LENFEFLKVLGKGTFGKVILCREKATAKLYAIKILKKEV 301 Query: 340 RIDENVFREIVNH----RSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRF 507 I ++ + +S HP +I K T L VM+Y GGELF + F Sbjct: 302 IIQKDEVAHTLTESRVLKSTNHPFLISLKYSFQTNDRLCFVMQYVNGGELFWHLSHERIF 361 Query: 508 HEDEARYFFQQLVCGVSFCHA 570 ED R++ +++ + + H+ Sbjct: 362 TEDRTRFYGAEIISALGYLHS 382
>KCC1A_HUMAN (Q14012) Calcium/calmodulin-dependent protein kinase type 1 (EC| 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha) Length = 370 Score = 58.5 bits (140), Expect = 1e-08 Identities = 35/116 (30%), Positives = 63/116 (54%), Gaps = 2/116 (1%) Frame = +1 Query: 226 DKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFI--ERGYRIDENVFREIVNHRSLRHPN 399 D Y+ +G+G F L ++ T++LVA+K I E + ++ EI ++HPN Sbjct: 18 DIYDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKEALEGKEGSMENEIAVLHKIKHPN 77 Query: 400 IIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCH 567 I+ ++ + HL ++M+ +GGELF+RI + G + E +A Q++ V + H Sbjct: 78 IVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLH 133
>AKT3_MOUSE (Q9WUA6) RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-gamma) (Protein kinase Akt-3) (Protein kinase B, gamma) (PKB gamma) Length = 479 Score = 58.5 bits (140), Expect = 1e-08 Identities = 38/146 (26%), Positives = 67/146 (45%), Gaps = 4/146 (2%) Frame = +1 Query: 145 CSAPASREIATHRKTSNRSRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKF 324 CS + + + + +R M+ ++ ++ +G G FG L+R + + + AMK Sbjct: 119 CSPTSQIDNIGEEEMDASTTHHKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKI 178 Query: 325 IERGYRI-DENVFREIVNHRSL---RHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERIC 492 +++ I + V + R L RHP + K T L VMEY GGELF + Sbjct: 179 LKKEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLS 238 Query: 493 DAGRFHEDEARYFFQQLVCGVSFCHA 570 F ED R++ ++V + + H+ Sbjct: 239 RERVFSEDRTRFYGAEIVSALDYLHS 264
>AKT3_HUMAN (Q9Y243) RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-gamma) (Protein kinase Akt-3) (Protein kinase B, gamma) (PKB gamma) (STK-2) Length = 479 Score = 58.5 bits (140), Expect = 1e-08 Identities = 38/146 (26%), Positives = 67/146 (45%), Gaps = 4/146 (2%) Frame = +1 Query: 145 CSAPASREIATHRKTSNRSRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKF 324 CS + + + + +R M+ ++ ++ +G G FG L+R + + + AMK Sbjct: 119 CSPTSQIDNIGEEEMDASTTHHKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKI 178 Query: 325 IERGYRI-DENVFREIVNHRSL---RHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERIC 492 +++ I + V + R L RHP + K T L VMEY GGELF + Sbjct: 179 LKKEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLS 238 Query: 493 DAGRFHEDEARYFFQQLVCGVSFCHA 570 F ED R++ ++V + + H+ Sbjct: 239 RERVFSEDRTRFYGAEIVSALDYLHS 264
>ARK1_SCHPO (O59790) Serine/threonine-protein kinase ark1 (EC 2.7.11.1)| (Aurora-related kinase 1) Length = 355 Score = 58.5 bits (140), Expect = 1e-08 Identities = 34/116 (29%), Positives = 61/116 (52%), Gaps = 4/116 (3%) Frame = +1 Query: 232 YEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGY----RIDENVFREIVNHRSLRHPN 399 +E + +G G FG L + + T +VA+K + + +I++ V REI +LRH N Sbjct: 89 FEIGKPLGKGKFGRVYLAKEKKTGFIVALKTLHKSELVQSKIEKQVRREIEIQSNLRHKN 148 Query: 400 IIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCH 567 I+R + +++E+A GEL++ + A RF E+ A + Q+ +S+ H Sbjct: 149 ILRLYGHFHDEKRIYLILEFAGRGELYQHLRRAKRFSEEVASKYIFQMANALSYLH 204
>KIN2_YEAST (P13186) Serine/threonine-protein kinase KIN2 (EC 2.7.11.1)| Length = 1147 Score = 58.5 bits (140), Expect = 1e-08 Identities = 36/153 (23%), Positives = 64/153 (41%), Gaps = 30/153 (19%) Frame = +1 Query: 202 RERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRI------------ 345 R+ R + +E + +G+G+ G KL+++R T+E+ +K + R + Sbjct: 89 RQFHRRSLGDWEFLETVGAGSMGKVKLVKHRQTKEICVIKIVNRASKAYLHKQHSLPSPK 148 Query: 346 ------------------DENVFREIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGG 471 D+ RE + L HP+I R E+ H ++ EY +GG Sbjct: 149 NESEILERQKRLEKEIARDKRTVREASLGQILYHPHICRLFEMCTMSNHFYMLFEYVSGG 208 Query: 472 ELFERICDAGRFHEDEARYFFQQLVCGVSFCHA 570 +L + I G E AR F + + + + HA Sbjct: 209 QLLDYIIQHGSLKEHHARKFARGIASALQYLHA 241
>AKT3_RAT (Q63484) RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-gamma) (Protein kinase Akt-3) (Protein kinase B, gamma) (PKB gamma) Length = 454 Score = 58.5 bits (140), Expect = 1e-08 Identities = 38/146 (26%), Positives = 67/146 (45%), Gaps = 4/146 (2%) Frame = +1 Query: 145 CSAPASREIATHRKTSNRSRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKF 324 CS + + + + +R M+ ++ ++ +G G FG L+R + + + AMK Sbjct: 119 CSPTSQIDNIGEEEMDASTTHHKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKI 178 Query: 325 IERGYRI-DENVFREIVNHRSL---RHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERIC 492 +++ I + V + R L RHP + K T L VMEY GGELF + Sbjct: 179 LKKEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLS 238 Query: 493 DAGRFHEDEARYFFQQLVCGVSFCHA 570 F ED R++ ++V + + H+ Sbjct: 239 RERVFSEDRTRFYGAEIVSALDYLHS 264
>ATG1_COLLN (P87248) Serine/threonine-protein kinase ATG1 (EC 2.7.11.1)| (Autophagy-related protein 1) (Colletotrichum lindemuthianum kinase 1) Length = 675 Score = 58.5 bits (140), Expect = 1e-08 Identities = 45/158 (28%), Positives = 72/158 (45%), Gaps = 27/158 (17%) Frame = +1 Query: 169 IATHRKTSNRSRERERSG---MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGY 339 +A TS S R R G + ++ EIG G+F +++++ VA+K +E G Sbjct: 1 MADRLPTSTSSGRRRRDGDASIGEFVIGGEIGKGSFAQVYSGHHKNSKAAVAIKSVEMGR 60 Query: 340 ---RIDENVFREIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGR-- 504 ++ EN++ EI ++LRHP+I+ + V + TH+ +VMEY G+L I R Sbjct: 61 LNNKLRENLYGEIQILKTLRHPHIVALHDCVESATHINLVMEYCELGDLSFFIKKRDRHG 120 Query: 505 -------------------FHEDEARYFFQQLVCGVSF 561 HE R+F QQL + F Sbjct: 121 TNAATEDMARKYPVTPGSGLHEVVTRHFLQQLASALKF 158
>STK6_RAT (P59241) Serine/threonine-protein kinase 6 (EC 2.7.11.1) (Aurora-A)| (ratAurA) Length = 397 Score = 58.2 bits (139), Expect = 2e-08 Identities = 34/142 (23%), Positives = 74/142 (52%), Gaps = 4/142 (2%) Frame = +1 Query: 157 ASREIATHRKTSNRSRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERG 336 + +E + +KT + S++R+ + ++ ++ R +G G FG L R + ++ ++A+K + + Sbjct: 103 SEKEQTSIQKTED-SKKRQWT-LEDFDIGRPLGKGKFGNVYLAREKQSKFILALKVLFKV 160 Query: 337 YR----IDENVFREIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGR 504 ++ + RE+ LRHPNI+R T + +++EYA G ++ + + Sbjct: 161 QLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK 220 Query: 505 FHEDEARYFFQQLVCGVSFCHA 570 F E + +L +S+CH+ Sbjct: 221 FDEQRTATYITELANALSYCHS 242
>KCC1A_RAT (Q63450) Calcium/calmodulin-dependent protein kinase type 1 (EC| 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha) Length = 374 Score = 58.2 bits (139), Expect = 2e-08 Identities = 34/116 (29%), Positives = 63/116 (54%), Gaps = 2/116 (1%) Frame = +1 Query: 226 DKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDE--NVFREIVNHRSLRHPN 399 D Y+ +G+G F L ++ T++LVA+K I + + ++ EI ++HPN Sbjct: 18 DIYDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKKALEGKEGSMENEIAVLHKIKHPN 77 Query: 400 IIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCH 567 I+ ++ + HL ++M+ +GGELF+RI + G + E +A Q++ V + H Sbjct: 78 IVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLH 133
>KCC1A_MOUSE (Q91YS8) Calcium/calmodulin-dependent protein kinase type 1 (EC| 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha) Length = 374 Score = 58.2 bits (139), Expect = 2e-08 Identities = 34/116 (29%), Positives = 63/116 (54%), Gaps = 2/116 (1%) Frame = +1 Query: 226 DKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDE--NVFREIVNHRSLRHPN 399 D Y+ +G+G F L ++ T++LVA+K I + + ++ EI ++HPN Sbjct: 18 DIYDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKKALEGKEGSMENEIAVLHKIKHPN 77 Query: 400 IIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCH 567 I+ ++ + HL ++M+ +GGELF+RI + G + E +A Q++ V + H Sbjct: 78 IVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLH 133
>HUNK_PANTR (Q68UT7) Hormonally up-regulated neu tumor-associated kinase (EC| 2.7.11.1) Length = 714 Score = 58.2 bits (139), Expect = 2e-08 Identities = 35/113 (30%), Positives = 58/113 (51%), Gaps = 5/113 (4%) Frame = +1 Query: 244 REIGSGNFGVAKLMRNRDTRELVAMKFIERGYR-----IDENVFREIVNHRSLRHPNIIR 408 R++G G+F + + T E VA+K I++ + +N+ RE + +RHPNI + Sbjct: 66 RKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIRHPNITQ 125 Query: 409 FKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCH 567 +++ T +VME GG L +I + R E EAR + +QL+ V H Sbjct: 126 LLDILETENSYYLVMELCPGGNLMHKIYEKKRLEESEARRYIRQLISAVEHLH 178
>HUNK_HUMAN (P57058) Hormonally up-regulated neu tumor-associated kinase (EC| 2.7.11.1) (Serine/threonine-protein kinase MAK-V) (B19) Length = 714 Score = 58.2 bits (139), Expect = 2e-08 Identities = 35/113 (30%), Positives = 58/113 (51%), Gaps = 5/113 (4%) Frame = +1 Query: 244 REIGSGNFGVAKLMRNRDTRELVAMKFIERGYR-----IDENVFREIVNHRSLRHPNIIR 408 R++G G+F + + T E VA+K I++ + +N+ RE + +RHPNI + Sbjct: 66 RKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIRHPNITQ 125 Query: 409 FKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCH 567 +++ T +VME GG L +I + R E EAR + +QL+ V H Sbjct: 126 LLDILETENSYYLVMELCPGGNLMHKIYEKKRLEESEARRYIRQLISAVEHLH 178
>SPEG_BRARE (Q696W0) Striated muscle preferentially expressed protein kinase (EC| 2.7.11.1) Length = 2995 Score = 58.2 bits (139), Expect = 2e-08 Identities = 36/142 (25%), Positives = 65/142 (45%), Gaps = 2/142 (1%) Frame = +1 Query: 148 SAPASREIATHRKTSNRSRERERSGMDK--YEPVREIGSGNFGVAKLMRNRDTRELVAMK 321 S+P +S +S R G+ + Y + E G FGV + R T ++ K Sbjct: 2652 SSPTPETPTGQAVSSTKSETTLRQGVPQKPYSFLDEKARGRFGVIRDCRENATGKMFIAK 2711 Query: 322 FIERGYRIDENVFREIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAG 501 I + + + +E +SLR I+ E +TP +L ++ EY +G E+ + + D Sbjct: 2712 IIPYDQQTKQTIIKEYEILKSLRCERIMALHEAYITPRYLVLITEYCSGKEILQNLIDRF 2771 Query: 502 RFHEDEARYFFQQLVCGVSFCH 567 + ED+ F Q++ G+ + H Sbjct: 2772 CYSEDDVVGFIVQILQGLEYLH 2793
>CDC2A_ARATH (P24100) Cell division control protein 2 homolog A (EC 2.7.11.22)| (EC 2.7.11.23) Length = 294 Score = 58.2 bits (139), Expect = 2e-08 Identities = 35/121 (28%), Positives = 65/121 (53%), Gaps = 5/121 (4%) Frame = +1 Query: 223 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFI---ERGYRIDENVFREIVNHRSLRH 393 MD+YE V +IG G +GV R++ T E +A+K I + + REI + ++H Sbjct: 1 MDQYEKVEKIGEGTYGVVYKARDKVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQH 60 Query: 394 PNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHED--EARYFFQQLVCGVSFCH 567 NI++ ++VV + L +V EY +L + + F +D + + Q++ G+++CH Sbjct: 61 SNIVKLQDVVHSEKRLYLVFEY-LDLDLKKHMDSTPDFSKDLHMIKTYLYQILRGIAYCH 119 Query: 568 A 570 + Sbjct: 120 S 120
>NEK1_HUMAN (Q96PY6) Serine/threonine-protein kinase Nek1 (EC 2.7.11.1)| (NimA-related protein kinase 1) (NY-REN-55 antigen) Length = 1258 Score = 58.2 bits (139), Expect = 2e-08 Identities = 38/120 (31%), Positives = 64/120 (53%), Gaps = 5/120 (4%) Frame = +1 Query: 223 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIE---RGYRIDENVFREIVNHRSLRH 393 M+KY +++IG G+FG A L+++ + +K I + E RE+ +++H Sbjct: 1 MEKYVRLQKIGEGSFGKAILVKSTEDGRQYVIKEINISRMSSKEREESRREVAVLANMKH 60 Query: 394 PNIIRFKEVVLTPTHLGIVMEYAAGGELFERI-CDAG-RFHEDEARYFFQQLVCGVSFCH 567 PNI++++E L IVM+Y GG+LF+RI G F ED+ +F Q+ + H Sbjct: 61 PNIVQYRESFEENGSLYIVMDYCEGGDLFKRINAQKGVLFQEDQILDWFVQICLALKHVH 120
>KPC1_CANAL (P43057) Protein kinase C-like 1 (EC 2.7.11.13) (PKC 1)| Length = 1097 Score = 58.2 bits (139), Expect = 2e-08 Identities = 31/135 (22%), Positives = 66/135 (48%), Gaps = 7/135 (5%) Frame = +1 Query: 184 KTSNRSRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFR 363 K+ R + + G+D ++ + +G GNFG L +R T +L A+K +++ + ++ + Sbjct: 754 KSGKSKRRKRKVGLDDFQFLAVLGKGNFGKVMLAESRHTSKLCAIKVLKKDFIVENDEAE 813 Query: 364 EIVNHRSL-------RHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEA 522 + + + + HP ++ T + VMEY +GG+L I RF A Sbjct: 814 SVKSEKRVFLTANKEMHPFLLNLHCCFQTENRIYFVMEYISGGDLMWHI-QKNRFTAKRA 872 Query: 523 RYFFQQLVCGVSFCH 567 +++ +++ G+ + H Sbjct: 873 KFYACEVLLGLKYFH 887
>CDK5_RAT (Q03114) Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein| kinase II catalytic subunit) (TPKII catalytic subunit) (Serine/threonine-protein kinase PSSALRE) Length = 292 Score = 58.2 bits (139), Expect = 2e-08 Identities = 35/121 (28%), Positives = 63/121 (52%), Gaps = 5/121 (4%) Frame = +1 Query: 223 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFI---ERGYRIDENVFREIVNHRSLRH 393 M KYE + +IG G +G +NR+T E+VA+K + + + + REI + L+H Sbjct: 1 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH 60 Query: 394 PNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDA--GRFHEDEARYFFQQLVCGVSFCH 567 NI+R +V+ + L +V E+ + ++ D+ G + + QL+ G+ FCH Sbjct: 61 KNIVRLHDVLHSDKKLTLVFEFC--DQDLKKYFDSCNGDLDPEIVKSLLFQLLKGLGFCH 118 Query: 568 A 570 + Sbjct: 119 S 119
>KCC1_SCHPO (Q9P7I2) Calcium/calmodulin-dependent protein kinase type I (EC| 2.7.11.17) (CaMK-I) Length = 335 Score = 57.8 bits (138), Expect = 2e-08 Identities = 33/117 (28%), Positives = 55/117 (47%), Gaps = 4/117 (3%) Frame = +1 Query: 229 KYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFRE----IVNHRSLRHP 396 KY R +G G + + + +T ++ A K + + + F + I+ S HP Sbjct: 30 KYRVGRVLGGGTYATVREAVHIETNKMYAAKIMNKKMMEKKQDFVKNEIAILKRVSYEHP 89 Query: 397 NIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCH 567 NI+ + T +L ++ E A GGELF+RIC G F+E +A + V + H Sbjct: 90 NILHLVDFFETVNNLYLITELATGGELFDRICAKGSFYEADAAALMRTTTSAVKYLH 146
>CDC2_RAT (P39951) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 57.8 bits (138), Expect = 2e-08 Identities = 37/125 (29%), Positives = 67/125 (53%), Gaps = 9/125 (7%) Frame = +1 Query: 223 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFI-----ERGYRIDENVFREIVNHRSL 387 M+ Y + +IG G +GV R+R T ++VAMK I E G + REI + L Sbjct: 1 MEDYIKIEKIGEGTYGVVYKGRHRTTGQIVAMKKIRLESEEEG--VPSTAIREISLLKEL 58 Query: 388 RHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDA---GRFHEDE-ARYFFQQLVCGV 555 RHPNI+ ++V++ + L ++ E+ + ++ D+ G+F + + + Q++ G+ Sbjct: 59 RHPNIVSLQDVLMQDSRLYLIFEFLSMD--LKKYLDSIPPGQFMDSSLVKSYLYQILQGI 116 Query: 556 SFCHA 570 FCH+ Sbjct: 117 VFCHS 121
>LOK_DROME (O61267) Ovarian-specific serine/threonine-protein kinase Lok (EC| 2.7.11.1) (Protein loki) (dMNK) Length = 476 Score = 57.8 bits (138), Expect = 2e-08 Identities = 31/118 (26%), Positives = 60/118 (50%), Gaps = 10/118 (8%) Frame = +1 Query: 244 REIGSGNFGVAKLMRNRDTRELVAMKFIERG----------YRIDENVFREIVNHRSLRH 393 R++GSG +G+ +L+ + T + AMK +++ + + V E ++L H Sbjct: 178 RKLGSGAYGLVRLVYDTRTCQQFAMKIVKKNMLSGARPSTNFSDPDRVLNEAKIMKNLSH 237 Query: 394 PNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCH 567 P ++R ++V P + +V+E+ GG+L RI ED ++ +F Q+ V + H Sbjct: 238 PCVVRMHDIVDKPDSVYMVLEFMRGGDLLNRIISNKLLSEDISKLYFYQMCHAVKYLH 295
>MAST1_RAT (Q810W7) Microtubule-associated serine/threonine-protein kinase 1| (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase) Length = 1570 Score = 57.8 bits (138), Expect = 2e-08 Identities = 36/135 (26%), Positives = 65/135 (48%), Gaps = 4/135 (2%) Frame = +1 Query: 175 THRKTSNRSRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDEN 354 T S+ S+ ++ G ++ ++ I +G +G L+R+RDTR+ AMK I + I N Sbjct: 357 TSEGRSSTSKAKKPPGESDFDTIKLISNGAYGAVYLVRHRDTRQRFAMKKINKQNLILRN 416 Query: 355 VFREIVNHRSL----RHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEA 522 ++ R + +P ++ T HL +VMEY GG+ + + G + A Sbjct: 417 QIQQAFVERDILTFAENPFVVGMFCSFETRRHLCMVMEYVEGGDCATLLKNIGALPVEMA 476 Query: 523 RYFFQQLVCGVSFCH 567 R +F + V + + H Sbjct: 477 RMYFAETVLALEYLH 491
>KPC2_APLCA (Q16975) Calcium-independent protein kinase C (EC 2.7.11.13) (APL| II) Length = 743 Score = 57.8 bits (138), Expect = 2e-08 Identities = 39/137 (28%), Positives = 66/137 (48%), Gaps = 6/137 (4%) Frame = +1 Query: 175 THRKTSNRSRERE-RSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRI-D 348 T +S+RSR R + + ++ +G G+FG L + T E+ A+K +++ I D Sbjct: 383 TRSPSSDRSRSHHSRISLHDFNFIKVLGKGSFGKVMLAEKKGTDEVYAIKVLKKDVIIQD 442 Query: 349 ENVFREIVNHR----SLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHED 516 ++V + R S +HP + T L VMEY GG+L +I A +F E Sbjct: 443 DDVECTMTEKRILALSAKHPFLTALHSSFQTKERLFFVMEYVNGGDLMFQIQRARKFDEP 502 Query: 517 EARYFFQQLVCGVSFCH 567 AR++ ++ + F H Sbjct: 503 RARFYAAEVTLALMFLH 519
>KPC1B_CAEEL (P34885) Protein kinase C-like 1B (EC 2.7.11.13) (PKC1B)| Length = 707 Score = 57.8 bits (138), Expect = 2e-08 Identities = 38/135 (28%), Positives = 66/135 (48%), Gaps = 8/135 (5%) Frame = +1 Query: 187 TSNRSRERERSG---MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRI-DEN 354 TS+RS + G + + ++ +G G+FG L + T E+ A+K +++ + D++ Sbjct: 360 TSSRSASKVPGGTLSIHDFTFMKVLGKGSFGKVMLAERKGTDEVYAIKILKKDVIVQDDD 419 Query: 355 VFREIVNHRSL----RHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEA 522 V + R L +HP + T L VMEY GG+L +I A +F E A Sbjct: 420 VECTMCEKRILSLAAKHPFLTALHSSFQTSDRLFFVMEYVNGGDLMFQIQRARKFDESRA 479 Query: 523 RYFFQQLVCGVSFCH 567 R++ ++ C + F H Sbjct: 480 RFYAAEVTCALQFLH 494
>MAST1_MOUSE (Q9R1L5) Microtubule-associated serine/threonine-protein kinase 1| (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase) Length = 1566 Score = 57.8 bits (138), Expect = 2e-08 Identities = 36/135 (26%), Positives = 65/135 (48%), Gaps = 4/135 (2%) Frame = +1 Query: 175 THRKTSNRSRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDEN 354 T S+ S+ ++ G ++ ++ I +G +G L+R+RDTR+ AMK I + I N Sbjct: 356 TSEGRSSTSKAKKPPGESDFDTIKLISNGAYGAVYLVRHRDTRQRFAMKKINKQNLILRN 415 Query: 355 VFREIVNHRSL----RHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEA 522 ++ R + +P ++ T HL +VMEY GG+ + + G + A Sbjct: 416 QIQQAFVERDILTFAENPFVVGMFCSFETRRHLCMVMEYVEGGDCATLLKNIGALPVEMA 475 Query: 523 RYFFQQLVCGVSFCH 567 R +F + V + + H Sbjct: 476 RMYFAETVLALEYLH 490
>KIN82_YEAST (P25341) Probable serine/threonine-protein kinase KIN82 (EC| 2.7.11.1) Length = 720 Score = 57.4 bits (137), Expect = 3e-08 Identities = 32/124 (25%), Positives = 60/124 (48%), Gaps = 10/124 (8%) Frame = +1 Query: 232 YEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHRSL----RHPN 399 +E +R +G G+ G LMR RDT ++ A+K + + I + ++ + + HP Sbjct: 324 FEKIRLLGQGDVGKVYLMRERDTNQIFALKVLNKHEMIKRKKIKRVLTEQEILATSDHPF 383 Query: 400 IIRFKEVVLTPTHLGIVMEYAAGGELFERI------CDAGRFHEDEARYFFQQLVCGVSF 561 I+ T +L + MEY GGE F + C A E++A+++ ++V + + Sbjct: 384 IVTLYHSFQTKDYLYLCMEYCMGGEFFRALQTRKSKCIA----EEDAKFYASEVVAALEY 439 Query: 562 CHAM 573 H + Sbjct: 440 LHLL 443
>ST32A_MOUSE (Q8BGW6) Serine/threonine-protein kinase 32A (EC 2.7.11.1)| Length = 398 Score = 57.4 bits (137), Expect = 3e-08 Identities = 32/123 (26%), Positives = 60/123 (48%), Gaps = 4/123 (3%) Frame = +1 Query: 205 ERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRID----ENVFREIV 372 E E D +E +R IG G+FG ++R DT+++ AMK++ + ++ NVF+E+ Sbjct: 14 ENEDVNFDHFEILRAIGKGSFGKVCIVRKNDTKKMYAMKYMNKQKCVERNEVRNVFKELQ 73 Query: 373 NHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCG 552 + L HP ++ + +V++ GG+L + F ED + F +L Sbjct: 74 IMQGLEHPFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQNVHFQEDTVKLFICELAMA 133 Query: 553 VSF 561 + + Sbjct: 134 LDY 136
>CDC2_MOUSE (P11440) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 57.4 bits (137), Expect = 3e-08 Identities = 37/125 (29%), Positives = 67/125 (53%), Gaps = 9/125 (7%) Frame = +1 Query: 223 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFI-----ERGYRIDENVFREIVNHRSL 387 M+ Y + +IG G +GV R+R T ++VAMK I E G + REI + L Sbjct: 1 MEDYIKIEKIGEGTYGVVYKGRHRVTGQIVAMKKIRLESEEEG--VPSTAIREISLLKEL 58 Query: 388 RHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDA---GRFHEDE-ARYFFQQLVCGV 555 RHPNI+ ++V++ + L ++ E+ + ++ D+ G+F + + + Q++ G+ Sbjct: 59 RHPNIVSLQDVLMQDSRLYLIFEFLSMD--LKKYLDSIPPGQFMDSSLVKSYLHQILQGI 116 Query: 556 SFCHA 570 FCH+ Sbjct: 117 VFCHS 121
>MYLK2_RABIT (P07313) Myosin light chain kinase 2, skeletal/cardiac muscle (EC| 2.7.11.18) (MLCK2) Length = 607 Score = 57.4 bits (137), Expect = 3e-08 Identities = 38/110 (34%), Positives = 52/110 (47%), Gaps = 2/110 (1%) Frame = +1 Query: 250 IGSGNFGVAKLMRNRDTRELVAMKFIERGYRID-ENVFREIVNHRSLRHPNIIRFKEVVL 426 +G G FG + T +A K I++ D E V EI L H N+I+ + Sbjct: 302 LGGGKFGAVCTCTEKSTGLKLAAKVIKKQTPKDKEMVMLEIEVMNQLNHRNLIQLYAAIE 361 Query: 427 TPTHLGIVMEYAAGGELFERICDAG-RFHEDEARYFFQQLVCGVSFCHAM 573 TP + + MEY GGELFERI D E + F +Q+ G+ F H M Sbjct: 362 TPHEIVLFMEYIEGGELFERIVDEDYHLTEVDTMVFVRQICDGILFMHKM 411
>MYLK_HUMAN (Q15746) Myosin light chain kinase, smooth muscle and non-muscle| isozymes (EC 2.7.11.18) (MLCK) [Contains: Telokin (Kinase-related protein) (KRP)] Length = 1914 Score = 57.4 bits (137), Expect = 3e-08 Identities = 37/121 (30%), Positives = 61/121 (50%), Gaps = 2/121 (1%) Frame = +1 Query: 211 ERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIER-GYRIDENVFREIVNHRSL 387 E+ D Y+ +GSG FG + + TR++ A KF + + EN+ +EI L Sbjct: 1457 EQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCL 1516 Query: 388 RHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAG-RFHEDEARYFFQQLVCGVSFC 564 HP +++ + ++ +V+E +GGELFERI D E E + +Q+ GV + Sbjct: 1517 HHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYI 1576 Query: 565 H 567 H Sbjct: 1577 H 1577
>CDPK4_PLAYO (Q7RJG2) Calcium-dependent protein kinase 4 (EC 2.7.11.1)| Length = 527 Score = 57.4 bits (137), Expect = 3e-08 Identities = 32/118 (27%), Positives = 66/118 (55%), Gaps = 4/118 (3%) Frame = +1 Query: 226 DKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGY---RID-ENVFREIVNHRSLRH 393 ++Y+ ++ +G G+FG L +++ T A+K I + + + D +++ RE+ + L H Sbjct: 67 EQYKGIKILGKGSFGEVILSKDKHTGHEYAIKVISKKHVKRKTDKQSLLREVELLKMLDH 126 Query: 394 PNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCH 567 NI++ E + +V + +GGELF+ I RF+E +A +Q++ G+++ H Sbjct: 127 INIMKLYEFFEDNNYYYLVSDVYSGGELFDEIISRKRFYEVDAARIIKQVLSGITYMH 184
>CDPK4_PLABA (P62345) Calcium-dependent protein kinase 4 (EC 2.7.11.1) (PbCDPK4)| Length = 527 Score = 57.4 bits (137), Expect = 3e-08 Identities = 32/118 (27%), Positives = 66/118 (55%), Gaps = 4/118 (3%) Frame = +1 Query: 226 DKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGY---RID-ENVFREIVNHRSLRH 393 ++Y+ ++ +G G+FG L +++ T A+K I + + + D +++ RE+ + L H Sbjct: 67 EQYKGIKILGKGSFGEVILSKDKHTGHEYAIKVISKKHVKRKTDKQSLLREVELLKMLDH 126 Query: 394 PNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCH 567 NI++ E + +V + +GGELF+ I RF+E +A +Q++ G+++ H Sbjct: 127 INIMKLYEFFEDNNYYYLVSDVYSGGELFDEIISRKRFYEVDAARIIKQVLSGITYMH 184
>KPCD_CANFA (Q5PU49) Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta)| Length = 674 Score = 57.0 bits (136), Expect = 4e-08 Identities = 37/123 (30%), Positives = 61/123 (49%), Gaps = 5/123 (4%) Frame = +1 Query: 214 RSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGY-RIDENVFREIVNHRSL- 387 R +D + + +G G+FG L+ + +E A+K +++ ID++V +V R L Sbjct: 341 RCNIDNFIFHKVLGKGSFGKVLLVELKGKKEFFAIKALKKDVVLIDDDVECTMVEKRVLA 400 Query: 388 ---RHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVS 558 +P + T HL VME+ GG+L I D GRF A ++ ++VCG+ Sbjct: 401 LAWENPFLTHLFCTFQTKDHLFFVMEFLNGGDLMYHIQDKGRFELYRATFYAAEIVCGLQ 460 Query: 559 FCH 567 F H Sbjct: 461 FLH 463
>CDC2_BOVIN (P48734) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 57.0 bits (136), Expect = 4e-08 Identities = 36/125 (28%), Positives = 67/125 (53%), Gaps = 9/125 (7%) Frame = +1 Query: 223 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFI-----ERGYRIDENVFREIVNHRSL 387 M+ Y + +IG G +GV R++ T ++VAMK I E G + REI + L Sbjct: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEG--VPSTAIREISLLKEL 58 Query: 388 RHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDA---GRFHEDE-ARYFFQQLVCGV 555 RHPNI+ ++V++ + L ++ E+ + ++ D+ G+F + + + Q++ G+ Sbjct: 59 RHPNIVSLQDVLMQDSRLYLIFEFLSMD--LKKYLDSIPPGQFMDSSLVKSYLYQILQGI 116 Query: 556 SFCHA 570 FCH+ Sbjct: 117 VFCHS 121
>STK33_HUMAN (Q9BYT3) Serine/threonine-protein kinase 33 (EC 2.7.11.1)| Length = 514 Score = 57.0 bits (136), Expect = 4e-08 Identities = 33/111 (29%), Positives = 59/111 (53%), Gaps = 3/111 (2%) Frame = +1 Query: 244 REIGSGNFGVAKLMRNRDTRELVAMKFIER---GYRIDENVFREIVNHRSLRHPNIIRFK 414 R +G G+FG+ +++T A+K + + G + + RE+ +S++H +II + Sbjct: 120 RILGKGSFGIVIEATDKETETKWAIKKVNKEKAGSSAVKLLEREVNILKSVKHEHIIHLE 179 Query: 415 EVVLTPTHLGIVMEYAAGGELFERICDAGRFHEDEARYFFQQLVCGVSFCH 567 +V TP + +VME GEL E + G F E+E R+ Q L +++ H Sbjct: 180 QVFETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLH 230 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 58,070,230 Number of Sequences: 219361 Number of extensions: 1187189 Number of successful extensions: 7505 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 6500 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 6901 length of database: 80,573,946 effective HSP length: 106 effective length of database: 57,321,680 effective search space used: 4815021120 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)