ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | bart13e08 |
|---|---|
| Clone Library Name | barley_pub |
>IDH3A_CAEEL (Q93714) Probable isocitrate dehydrogenase [NAD] subunit alpha,| mitochondrial precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) Length = 358 Score = 99.0 bits (245), Expect = 8e-21 Identities = 56/132 (42%), Positives = 78/132 (59%), Gaps = 5/132 (3%) Frame = +3 Query: 174 ARRTVTYMPRPGDGTPRPVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDV-----HG 338 A TV R G R VTLIPGDGIGP ++ +V+++ EA AP+ ++ DV Sbjct: 9 ASSTVGQSIRYSSGDVRRVTLIPGDGIGPEISASVQKIFEAADAPIAWDPVDVTPVKGRD 68 Query: 339 DMPAVPPAVIESIRRNKVCLKGGLATPVGGGVSSLNMQLRKELDLFASLVNCANVPGLPT 518 + +P IE + NKV LKG L TP+G G SLN+ +RKE L+A++ C ++ G T Sbjct: 69 GVFRIPSRCIELMHANKVGLKGPLETPIGKGHRSLNLAVRKEFSLYANVRPCRSLEGHKT 128 Query: 519 RHKNVDIVVIRE 554 + NVD+V IRE Sbjct: 129 LYDNVDVVTIRE 140
>IDH3A_DROME (Q9VWH4) Probable isocitrate dehydrogenase [NAD] subunit alpha,| mitochondrial precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) Length = 377 Score = 97.8 bits (242), Expect = 2e-20 Identities = 51/116 (43%), Positives = 74/116 (63%), Gaps = 5/116 (4%) Frame = +3 Query: 222 RPVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVH-----GDMPAVPPAVIESIRRN 386 + VTLIPGDGIGP ++ AV+++ A + P+ +E DV +P A I+S+ N Sbjct: 48 KKVTLIPGDGIGPEISAAVQKIFTAANVPIEWEAVDVTPVRGPDGKFGIPQAAIDSVNTN 107 Query: 387 KVCLKGGLATPVGGGVSSLNMQLRKELDLFASLVNCANVPGLPTRHKNVDIVVIRE 554 K+ LKG L TPVG G SLN+ LRKE +L+A++ C ++ G T + +VD+V IRE Sbjct: 108 KIGLKGPLMTPVGKGHRSLNLALRKEFNLYANVRPCRSLEGYKTLYDDVDVVTIRE 163
>IDH1_SCHPO (O13696) Isocitrate dehydrogenase [NAD] subunit 1, mitochondrial| precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) Length = 356 Score = 97.4 bits (241), Expect = 2e-20 Identities = 58/117 (49%), Positives = 74/117 (63%), Gaps = 8/117 (6%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHG-------DMPAVPPAVIESIRRN 386 VTLIPGDGIG + AV ++ + + P+ FE DV G A+ A I+S++RN Sbjct: 23 VTLIPGDGIGRETSNAVTEIFKTANVPIEFEEIDVTGMEKNNKSSGDALHEA-IQSLKRN 81 Query: 387 KVCLKGGLATPVG-GGVSSLNMQLRKELDLFASLVNCANVPGLPTRHKNVDIVVIRE 554 KV LKG L TP GG +S N+ LRKELD++ASLV N+PG TRH NVD +IRE Sbjct: 82 KVGLKGILFTPFEKGGHTSFNVALRKELDIYASLVLIKNIPGFKTRHDNVDFAIIRE 138
>LEU3_SOLTU (P29696) 3-isopropylmalate dehydrogenase, chloroplast precursor (EC| 1.1.1.85) (Beta-IPM dehydrogenase) (IMDH) (3-IPM-DH) Length = 357 Score = 94.0 bits (232), Expect = 3e-19 Identities = 48/113 (42%), Positives = 74/113 (65%), Gaps = 5/113 (4%) Frame = +3 Query: 231 TLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHGDMPAVPPAVI-----ESIRRNKVC 395 TL PGDGIGP + +V Q+ + P+ +E + V ++ + + ES+RRNKV Sbjct: 40 TLFPGDGIGPEIAESVRQIFKVAEVPIEWEEHYVGTEVDPRTNSFLTWESLESVRRNKVG 99 Query: 396 LKGGLATPVGGGVSSLNMQLRKELDLFASLVNCANVPGLPTRHKNVDIVVIRE 554 LKG +ATP+G G SLN+ LRKEL+L+A++ C ++PG TR+ +V+++ IRE Sbjct: 100 LKGPMATPIGKGHRSLNLTLRKELNLYANVRPCYSLPGYKTRYDDVNLITIRE 152
>IDH3A_BOVIN (P41563) Isocitrate dehydrogenase [NAD] subunit alpha,| mitochondrial precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) (Isocitrate dehydrogenase subunits 3/4) Length = 366 Score = 94.0 bits (232), Expect = 3e-19 Identities = 53/133 (39%), Positives = 78/133 (58%), Gaps = 5/133 (3%) Frame = +3 Query: 171 GARRTVTYMPRPGDGTPRPVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVH----- 335 GA + R G + VTLIPGDGIGP ++ AV ++ +A AP+ +E +V Sbjct: 15 GAFHNQKQVTRGFAGGVKTVTLIPGDGIGPEISAAVMKIFDAAKAPIQWEERNVAAIQGP 74 Query: 336 GDMPAVPPAVIESIRRNKVCLKGGLATPVGGGVSSLNMQLRKELDLFASLVNCANVPGLP 515 G +PP ES+ +NK+ LKG L TP+ G S+N+ LRK DL+A++ C ++ G Sbjct: 75 GGKWMIPPEAKESMDKNKMGLKGPLKTPIAAGHPSMNLLLRKTFDLYANVRPCVSIEGYK 134 Query: 516 TRHKNVDIVVIRE 554 T + +V+IV IRE Sbjct: 135 TPYHDVNIVTIRE 147
>IDH3A_RAT (Q99NA5) Isocitrate dehydrogenase [NAD] subunit alpha,| mitochondrial precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) Length = 366 Score = 93.2 bits (230), Expect = 4e-19 Identities = 52/133 (39%), Positives = 78/133 (58%), Gaps = 5/133 (3%) Frame = +3 Query: 171 GARRTVTYMPRPGDGTPRPVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVH----- 335 GA + R G + VTLIPGDGIGP ++ +V ++ +A AP+ +E +V Sbjct: 15 GAFHNTKQVTRGFAGGVQTVTLIPGDGIGPEISASVMKIFDAAKAPIQWEERNVTAIQGP 74 Query: 336 GDMPAVPPAVIESIRRNKVCLKGGLATPVGGGVSSLNMQLRKELDLFASLVNCANVPGLP 515 G +PP ES+ +NK+ LKG L TP+ G S+N+ LRK DL+A++ C ++ G Sbjct: 75 GGKWMIPPEAKESMDKNKMGLKGPLKTPIAAGHPSMNLLLRKTFDLYANVRPCVSIEGYK 134 Query: 516 TRHKNVDIVVIRE 554 T + +V+IV IRE Sbjct: 135 TPYTDVNIVTIRE 147
>IDH3A_MOUSE (Q9D6R2) Isocitrate dehydrogenase [NAD] subunit alpha,| mitochondrial precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) Length = 366 Score = 93.2 bits (230), Expect = 4e-19 Identities = 52/133 (39%), Positives = 78/133 (58%), Gaps = 5/133 (3%) Frame = +3 Query: 171 GARRTVTYMPRPGDGTPRPVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVH----- 335 GA + R G + VTLIPGDGIGP ++ +V ++ +A AP+ +E +V Sbjct: 15 GAFHNTKQVTRGFAGGVQTVTLIPGDGIGPEISASVMKIFDAAKAPIQWEERNVTAIQGP 74 Query: 336 GDMPAVPPAVIESIRRNKVCLKGGLATPVGGGVSSLNMQLRKELDLFASLVNCANVPGLP 515 G +PP ES+ +NK+ LKG L TP+ G S+N+ LRK DL+A++ C ++ G Sbjct: 75 GGKWMIPPEAKESMDKNKMGLKGPLKTPIAAGHPSMNLLLRKTFDLYANVRPCVSIEGYK 134 Query: 516 TRHKNVDIVVIRE 554 T + +V+IV IRE Sbjct: 135 TPYTDVNIVTIRE 147
>IDH2_YEAST (P28241) Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial| precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) Length = 369 Score = 92.4 bits (228), Expect = 8e-19 Identities = 49/126 (38%), Positives = 77/126 (61%), Gaps = 5/126 (3%) Frame = +3 Query: 192 YMPRPGDGTPR-PVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVH----GDMPAVP 356 Y +P T + V+ I GDGIGP ++ +V+++ A + P+ +E+ DV + +P Sbjct: 26 YTGKPNPSTGKYTVSFIEGDGIGPEISKSVKKIFSAANVPIEWESCDVSPIFVNGLTTIP 85 Query: 357 PAVIESIRRNKVCLKGGLATPVGGGVSSLNMQLRKELDLFASLVNCANVPGLPTRHKNVD 536 ++SI +N V LKG LATP+G G SLN+ LRK LFA++ ++ G T ++NVD Sbjct: 86 DPAVQSITKNLVALKGPLATPIGKGHRSLNLTLRKTFGLFANVRPAKSIEGFKTTYENVD 145 Query: 537 IVVIRE 554 +V+IRE Sbjct: 146 LVLIRE 151
>IDH2_SCHPO (Q9USP8) Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial| precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) Length = 378 Score = 90.9 bits (224), Expect = 2e-18 Identities = 47/113 (41%), Positives = 70/113 (61%), Gaps = 4/113 (3%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVH----GDMPAVPPAVIESIRRNKVC 395 VT+I GDGIGP + +VE++ +A P+ +E V+ +P ES+R+NKV Sbjct: 48 VTMIAGDGIGPEIAQSVERIFKAAKVPIEWERVKVYPILKNGTTTIPDDAKESVRKNKVA 107 Query: 396 LKGGLATPVGGGVSSLNMQLRKELDLFASLVNCANVPGLPTRHKNVDIVVIRE 554 LKG LATP+G G S+N+ LR+ LFA++ C ++ G T + NV+ V+IRE Sbjct: 108 LKGPLATPIGKGHVSMNLTLRRTFGLFANVRPCVSITGYKTPYDNVNTVLIRE 160
>IDH3A_PONPY (Q5R678) Isocitrate dehydrogenase [NAD] subunit alpha,| mitochondrial precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) Length = 366 Score = 90.9 bits (224), Expect = 2e-18 Identities = 52/133 (39%), Positives = 77/133 (57%), Gaps = 5/133 (3%) Frame = +3 Query: 171 GARRTVTYMPRPGDGTPRPVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVH----- 335 GA + R G + VTLIPGDGIGP ++ AV ++ +A AP+ +E +V Sbjct: 15 GAFHNPKQVTRGFTGGVQTVTLIPGDGIGPEISAAVMKIFDAAKAPIQWEERNVTAIQGP 74 Query: 336 GDMPAVPPAVIESIRRNKVCLKGGLATPVGGGVSSLNMQLRKELDLFASLVNCANVPGLP 515 G +P ES+ +NK+ LKG L TP+ G S+N+ LRK DL+A++ C ++ G Sbjct: 75 GGKWMIPSEAKESMDKNKMGLKGPLKTPIAAGHPSMNLLLRKTFDLYANVRPCVSIEGYK 134 Query: 516 TRHKNVDIVVIRE 554 T + +V+IV IRE Sbjct: 135 TPYTDVNIVTIRE 147
>IDH3A_HUMAN (P50213) Isocitrate dehydrogenase [NAD] subunit alpha,| mitochondrial precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) Length = 366 Score = 90.9 bits (224), Expect = 2e-18 Identities = 52/133 (39%), Positives = 77/133 (57%), Gaps = 5/133 (3%) Frame = +3 Query: 171 GARRTVTYMPRPGDGTPRPVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVH----- 335 GA + R G + VTLIPGDGIGP ++ AV ++ +A AP+ +E +V Sbjct: 15 GAFHNPKQVTRGFTGGVQTVTLIPGDGIGPEISAAVMKIFDAAKAPIQWEERNVTAIQGP 74 Query: 336 GDMPAVPPAVIESIRRNKVCLKGGLATPVGGGVSSLNMQLRKELDLFASLVNCANVPGLP 515 G +P ES+ +NK+ LKG L TP+ G S+N+ LRK DL+A++ C ++ G Sbjct: 75 GGKWMIPSEAKESMDKNKMGLKGPLKTPIAAGHPSMNLLLRKTFDLYANVRPCVSIEGYK 134 Query: 516 TRHKNVDIVVIRE 554 T + +V+IV IRE Sbjct: 135 TPYTDVNIVTIRE 147
>IDH1_AJECA (O13302) Isocitrate dehydrogenase [NAD] subunit 1, mitochondrial| precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) Length = 388 Score = 90.1 bits (222), Expect = 4e-18 Identities = 53/116 (45%), Positives = 72/116 (62%), Gaps = 7/116 (6%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHG------DMPAVPPAVIESIRRNK 389 VTLIPGDGIG V +V+ + +A + P+ +E DV G + I S++RNK Sbjct: 54 VTLIPGDGIGTEVAESVKTIFKADNVPIEWEQVDVSGLDAGNKHSEDLFKESIASLKRNK 113 Query: 390 VCLKGGLATPVG-GGVSSLNMQLRKELDLFASLVNCANVPGLPTRHKNVDIVVIRE 554 + LKG L TPV G S N+ LR+ELD++AS+V N+PG TRH NVD+ +IRE Sbjct: 114 LGLKGILHTPVERSGHQSFNVALRQELDIYASIVLIKNIPGYKTRHDNVDLCIIRE 169
>IDH3A_MACFA (Q28480) Isocitrate dehydrogenase [NAD] subunit alpha,| mitochondrial precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) (Fragment) Length = 347 Score = 90.1 bits (222), Expect = 4e-18 Identities = 49/119 (41%), Positives = 73/119 (61%), Gaps = 5/119 (4%) Frame = +3 Query: 213 GTPRPVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVH-----GDMPAVPPAVIESI 377 G + VTLIPGDGIGP ++ AV ++ +A AP+ +E +V G +P ES+ Sbjct: 10 GGVQTVTLIPGDGIGPEISAAVMKIFDAAKAPIQWEERNVTAIQGPGGKWMIPSEAKESM 69 Query: 378 RRNKVCLKGGLATPVGGGVSSLNMQLRKELDLFASLVNCANVPGLPTRHKNVDIVVIRE 554 +NK+ LKG L TP+ G S+N+ LRK DL+A++ C ++ G T + +V+IV IRE Sbjct: 70 DKNKMGLKGPLKTPIAAGHPSMNLLLRKTFDLYANVRPCVSIEGYKTPYTDVNIVTIRE 128
>IDH1_KLULA (O94229) Isocitrate dehydrogenase [NAD] subunit 1, mitochondrial| precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) Length = 361 Score = 90.1 bits (222), Expect = 4e-18 Identities = 50/111 (45%), Positives = 73/111 (65%), Gaps = 2/111 (1%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHG-DMPAVPPAVIESIRRNKVCLKG 404 VTLIPGDG+G VT +V ++ E + P+ +ET D+ G + +ES++RNKV LKG Sbjct: 32 VTLIPGDGVGKEVTDSVVKIFENENIPIDWETIDISGLENTENVQRAVESLKRNKVGLKG 91 Query: 405 GLATPVGG-GVSSLNMQLRKELDLFASLVNCANVPGLPTRHKNVDIVVIRE 554 TP G SLN+ LRK+LD+FA++ ++PG+ TR N+D+V+IRE Sbjct: 92 IWHTPADQTGHGSLNVALRKQLDIFANVALFKSIPGVKTRLNNIDMVIIRE 142
>IDH3B_RAT (Q68FX0) Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial| precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) Length = 385 Score = 89.4 bits (220), Expect = 6e-18 Identities = 47/116 (40%), Positives = 76/116 (65%), Gaps = 6/116 (5%) Frame = +3 Query: 225 PVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHGDMPAVPPA----VIESIRRNKV 392 PVT++PGDG+GP + AV++V +A PV F+ + + V+ S++ NKV Sbjct: 50 PVTMLPGDGVGPELMHAVKEVFKAAAVPVEFKEHHLSEVQNMASEEKLEQVLSSMKENKV 109 Query: 393 CLKGGLATPVG--GGVSSLNMQLRKELDLFASLVNCANVPGLPTRHKNVDIVVIRE 554 + G + TP+ G ++S +MQLR++LDLFA++V+ ++PG TRH N+D+V+IRE Sbjct: 110 AIIGKIYTPMEYKGELASYDMQLRRKLDLFANVVHVKSLPGYKTRHNNLDLVIIRE 165
>IDH3B_BOVIN (O77784) Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial| precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) (NAD(+)-isocitrate dehydrogenase subunit 1) (IDH1) Length = 385 Score = 88.6 bits (218), Expect = 1e-17 Identities = 46/116 (39%), Positives = 76/116 (65%), Gaps = 6/116 (5%) Frame = +3 Query: 225 PVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHGDMPAVPPA----VIESIRRNKV 392 PVT++PGDG+GP + AV++V +A PV F+ + + V+ S++ NKV Sbjct: 50 PVTMLPGDGVGPELMHAVKEVFKAASVPVEFQEHHLSEVQNMASEEKLEQVLSSMKENKV 109 Query: 393 CLKGGLATPVG--GGVSSLNMQLRKELDLFASLVNCANVPGLPTRHKNVDIVVIRE 554 + G + TP+ G ++S +M+LR++LDLFA++V+ ++PG TRH N+D+V+IRE Sbjct: 110 AIIGKIHTPMEYKGELASYDMRLRRKLDLFANVVHVKSLPGYKTRHNNLDLVIIRE 165
>IDH3B_MACFA (Q28479) Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial| precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) (Fragment) Length = 381 Score = 87.8 bits (216), Expect = 2e-17 Identities = 46/116 (39%), Positives = 76/116 (65%), Gaps = 6/116 (5%) Frame = +3 Query: 225 PVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHGDMPAVPPA----VIESIRRNKV 392 PVT++PGDG+GP + AV++V +A PV F+ + + V+ S++ NKV Sbjct: 48 PVTMLPGDGVGPELMHAVKEVFKAAAVPVEFQEHHLSEVQNMASEEKLEQVLSSMKENKV 107 Query: 393 CLKGGLATPVG--GGVSSLNMQLRKELDLFASLVNCANVPGLPTRHKNVDIVVIRE 554 + G + TP+ G ++S +M+LR++LDLFA++V+ ++PG TRH N+D+V+IRE Sbjct: 108 AIIGKIHTPMEYKGELASYDMRLRRKLDLFANVVHVKSLPGYMTRHNNLDLVIIRE 163
>IDH3B_PONPY (Q5RBT4) Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial| precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) Length = 385 Score = 87.8 bits (216), Expect = 2e-17 Identities = 46/116 (39%), Positives = 76/116 (65%), Gaps = 6/116 (5%) Frame = +3 Query: 225 PVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHGDMPAVPPA----VIESIRRNKV 392 PVT++PGDG+GP + AV++V +A PV F+ + + V+ S++ NKV Sbjct: 50 PVTMLPGDGVGPELMHAVKEVFKAAAVPVEFQEHHLSEVQNMASEEKLEQVLSSMKENKV 109 Query: 393 CLKGGLATPVG--GGVSSLNMQLRKELDLFASLVNCANVPGLPTRHKNVDIVVIRE 554 + G + TP+ G ++S +M+LR++LDLFA++V+ ++PG TRH N+D+V+IRE Sbjct: 110 AIIGKIHTPMEYKGELASYDMRLRRKLDLFANVVHVKSLPGYMTRHNNLDLVIIRE 165
>IDH3B_HUMAN (O43837) Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial| precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) Length = 385 Score = 87.8 bits (216), Expect = 2e-17 Identities = 46/116 (39%), Positives = 76/116 (65%), Gaps = 6/116 (5%) Frame = +3 Query: 225 PVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHGDMPAVPPA----VIESIRRNKV 392 PVT++PGDG+GP + AV++V +A PV F+ + + V+ S++ NKV Sbjct: 50 PVTMLPGDGVGPELMHAVKEVFKAAAVPVEFQEHHLSEVQNMASEEKLEQVLSSMKENKV 109 Query: 393 CLKGGLATPVG--GGVSSLNMQLRKELDLFASLVNCANVPGLPTRHKNVDIVVIRE 554 + G + TP+ G ++S +M+LR++LDLFA++V+ ++PG TRH N+D+V+IRE Sbjct: 110 AIIGKIHTPMEYKGELASYDMRLRRKLDLFANVVHVKSLPGYMTRHNNLDLVIIRE 165
>IDH2_KLULA (O94230) Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial| precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) Length = 368 Score = 86.3 bits (212), Expect = 5e-17 Identities = 46/124 (37%), Positives = 72/124 (58%), Gaps = 10/124 (8%) Frame = +3 Query: 213 GTPRP------VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVH----GDMPAVPPA 362 G P P V+ I GDG+GP ++ +V+ + A P+ +E+ DV + +P Sbjct: 27 GKPNPKTGKYTVSFIEGDGVGPEISKSVKAIFSAAKVPIEWESCDVSPIFVNGLTTIPDP 86 Query: 363 VIESIRRNKVCLKGGLATPVGGGVSSLNMQLRKELDLFASLVNCANVPGLPTRHKNVDIV 542 + SI +N + LKG LATP+G G SLN+ LRK LFA++ ++ G T ++NV++V Sbjct: 87 AVASINKNLIALKGPLATPIGKGHRSLNLTLRKTFGLFANVRPAKSIEGYKTTYENVNLV 146 Query: 543 VIRE 554 +IRE Sbjct: 147 LIRE 150
>IDH_THET8 (P33197) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 496 Score = 84.0 bits (206), Expect = 3e-16 Identities = 48/117 (41%), Positives = 68/117 (58%), Gaps = 8/117 (6%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDV------HGDMPAVPPAVIESIRRNK 389 +T+IPGDGIGP A +V+EA AP+ +E + G VP IESIR+ + Sbjct: 22 ITVIPGDGIGPECVEATLKVLEAAKAPLAYEVREAGASVFRRGIASGVPQETIESIRKTR 81 Query: 390 VCLKGGLATPVGGGVSSLNMQLRKELDLFASLVNCANVPGLPTRH--KNVDIVVIRE 554 V LKG L TPVG G S N+ LRK + +A++ P +PT + + +D+VV+RE Sbjct: 82 VVLKGPLETPVGYGEKSANVTLRKLFETYANVRPVREFPNVPTPYAGRGIDLVVVRE 138
>IDH3G_RAT (P41565) Isocitrate dehydrogenase [NAD] subunit gamma,| mitochondrial precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) Length = 393 Score = 82.0 bits (201), Expect = 1e-15 Identities = 53/144 (36%), Positives = 82/144 (56%), Gaps = 4/144 (2%) Frame = +3 Query: 135 VASAPSLPGHGGGARRTVTYMPRPGDGTPRPVTLIPGDGIGPLVTGAVEQVMEAMHAPVY 314 V +A P +++T+ P G VT+IPGDGIGP + V+ V PV Sbjct: 28 VLAAHEAPRRSISSQQTIP--PSAKYGGRHTVTMIPGDGIGPELMLHVKSVFRHACVPVD 85 Query: 315 FETYDV--HGDMPAVPPAVIESIRRNKVCLKGGLAT--PVGGGVSSLNMQLRKELDLFAS 482 FE V + D + A++ +IRRN+V LKG + T + S N LR LDL+A+ Sbjct: 86 FEEVHVSSNADEEDIRNAIM-AIRRNRVALKGNIETNHDLPPSHKSRNNILRTSLDLYAN 144 Query: 483 LVNCANVPGLPTRHKNVDIVVIRE 554 +++C ++PG+ TRHK++DI+++RE Sbjct: 145 VIHCKSLPGVVTRHKDIDILIVRE 168
>IDH3G_MACFA (P41564) Isocitrate dehydrogenase [NAD] subunit gamma,| mitochondrial precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) (Fragment) Length = 355 Score = 81.3 bits (199), Expect = 2e-15 Identities = 50/126 (39%), Positives = 74/126 (58%), Gaps = 4/126 (3%) Frame = +3 Query: 189 TYMPRPGDGTPRPVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDV--HGDMPAVPPA 362 T P G VT+IPGDGIGP + V+ V PV FE V + D + A Sbjct: 6 TIPPSAKYGGRHTVTMIPGDGIGPELMLHVKSVFRHACVPVDFEEVHVSSNADEEDIRNA 65 Query: 363 VIESIRRNKVCLKGGLATP--VGGGVSSLNMQLRKELDLFASLVNCANVPGLPTRHKNVD 536 ++ +IRRN+V LKG + T + S N LR LDL+A++++C ++PG+ TRHK++D Sbjct: 66 IM-AIRRNRVALKGNIETNHNLPPSHKSRNNILRTSLDLYANVIHCKSLPGVVTRHKDID 124 Query: 537 IVVIRE 554 I+++RE Sbjct: 125 ILIVRE 130
>IDH3G_MOUSE (P70404) Isocitrate dehydrogenase [NAD] subunit gamma,| mitochondrial precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) Length = 393 Score = 81.3 bits (199), Expect = 2e-15 Identities = 50/126 (39%), Positives = 74/126 (58%), Gaps = 4/126 (3%) Frame = +3 Query: 189 TYMPRPGDGTPRPVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDV--HGDMPAVPPA 362 T P G VT+IPGDGIGP + V+ V PV FE V + D + A Sbjct: 44 TIPPSAKYGGRHTVTMIPGDGIGPELMLHVKSVFRHACVPVDFEEVHVSSNADEEDIRNA 103 Query: 363 VIESIRRNKVCLKGGLATP--VGGGVSSLNMQLRKELDLFASLVNCANVPGLPTRHKNVD 536 ++ +IRRN+V LKG + T + S N LR LDL+A++++C ++PG+ TRHK++D Sbjct: 104 IM-AIRRNRVALKGNIETNHNLPPSHKSRNNILRTSLDLYANVIHCKSLPGVVTRHKDID 162 Query: 537 IVVIRE 554 I+++RE Sbjct: 163 ILIVRE 168
>IDH3G_HUMAN (P51553) Isocitrate dehydrogenase [NAD] subunit gamma,| mitochondrial precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) Length = 393 Score = 81.3 bits (199), Expect = 2e-15 Identities = 50/126 (39%), Positives = 74/126 (58%), Gaps = 4/126 (3%) Frame = +3 Query: 189 TYMPRPGDGTPRPVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDV--HGDMPAVPPA 362 T P G VT+IPGDGIGP + V+ V PV FE V + D + A Sbjct: 44 TIPPSAKYGGRHTVTMIPGDGIGPELMLHVKSVFRHACVPVDFEEVHVSSNADEEDIRNA 103 Query: 363 VIESIRRNKVCLKGGLATP--VGGGVSSLNMQLRKELDLFASLVNCANVPGLPTRHKNVD 536 ++ +IRRN+V LKG + T + S N LR LDL+A++++C ++PG+ TRHK++D Sbjct: 104 IM-AIRRNRVALKGNIETNHNLPPSHKSRNNILRTSLDLYANVIHCKSLPGVVTRHKDID 162 Query: 537 IVVIRE 554 I+++RE Sbjct: 163 ILIVRE 168
>IDH1_YEAST (P28834) Isocitrate dehydrogenase [NAD] subunit 1, mitochondrial| precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) Length = 360 Score = 80.9 bits (198), Expect = 2e-15 Identities = 45/111 (40%), Positives = 71/111 (63%), Gaps = 2/111 (1%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDV-HGDMPAVPPAVIESIRRNKVCLKG 404 VTLIPGDG+G +T +V + EA + P+ +ET ++ D +ES++RNK+ LKG Sbjct: 31 VTLIPGDGVGKEITDSVRTIFEAENIPIDWETINIKQTDHKEGVYEAVESLKRNKIGLKG 90 Query: 405 GLATPVGG-GVSSLNMQLRKELDLFASLVNCANVPGLPTRHKNVDIVVIRE 554 TP G SLN+ LRK+LD++A++ ++ G+ TR ++D++VIRE Sbjct: 91 LWHTPADQTGHGSLNVALRKQLDIYANVALFKSLKGVKTRIPDIDLIVIRE 141
>IDH3B_CAEEL (Q93353) Probable isocitrate dehydrogenase [NAD] subunit beta,| mitochondrial precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) Length = 379 Score = 75.1 bits (183), Expect = 1e-13 Identities = 56/162 (34%), Positives = 85/162 (52%), Gaps = 17/162 (10%) Frame = +3 Query: 120 LLRRLVAS----APSLPG--HGGGARRTVTYMPRPGDGTPRP--VTLIPGDGIGPLVTGA 275 +L R V+S AP G + +R+ PRP + VT+IPGDG+GP + Sbjct: 1 MLSRTVSSLSRVAPQTLGAVNAASSRQYSITAPRPPTELNQKLKVTIIPGDGVGPELIYT 60 Query: 276 VEQVMEAMHAPVYFETY---DVHGDMPAVPPAVIESI-RRNKVCLKGGLATPV----GGG 431 V+ +++ P+ FE +VH + +ESI R N V LKG + G Sbjct: 61 VQDIVKQTGIPIEFEEIFLSEVHYTRSSSIENAVESIGRNNNVALKGAIEESAVLHTEGE 120 Query: 432 VSSLNMQLRKELDLFASLVNCANVPGLPTRH-KNVDIVVIRE 554 + LNM+LR+ LDLFA++V+ + G+ TRH K +D V++RE Sbjct: 121 LQGLNMRLRRSLDLFANVVHIKTLDGIKTRHGKQLDFVIVRE 162
>IDH_ANASP (P50214) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 473 Score = 74.3 bits (181), Expect = 2e-13 Identities = 46/126 (36%), Positives = 67/126 (53%), Gaps = 17/126 (13%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHAPVY--------FETY------DVHGDMPAVPPAV 365 + I GDG G + A E+V++A A Y F+ Y D++G +P Sbjct: 29 IPFIRGDGTGIDIWPATEKVLDAAVAKAYQGKRKISWFKVYAGDEACDLYGTYQYLPEDT 88 Query: 366 IESIRRNKVCLKGGLATPVGGGVSSLNMQLRKELDLFASLVNCANVPGLPTRHKN---VD 536 + +IR V +KG L TPVGGG+ SLN+ LR+ DL+A + C G P+ HKN +D Sbjct: 89 LTAIREYGVAIKGPLTTPVGGGIRSLNVALRQIFDLYACVRPCRYYAGTPSPHKNPEKLD 148 Query: 537 IVVIRE 554 ++V RE Sbjct: 149 VIVYRE 154
>IDH_RICCN (Q92IR7) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 483 Score = 69.3 bits (168), Expect = 7e-12 Identities = 41/117 (35%), Positives = 63/117 (53%), Gaps = 7/117 (5%) Frame = +3 Query: 225 PVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHGDM------PAVPPAVIESIRRN 386 P+T+ GDGIGP + AV ++ A + ET +V + + ESI+R Sbjct: 6 PITIAYGDGIGPEIMEAVLYILRKAEARIRLETIEVGEKLYKKHYTSGISEESWESIQRT 65 Query: 387 KVCLKGGLATPVGGGVSSLNMQLRKELDLFASLVNCANV-PGLPTRHKNVDIVVIRE 554 + LK + TP GGG SLN+ +RK L LFA++ ++ P T H N+++ +IRE Sbjct: 66 GIILKAPITTPQGGGYKSLNVTIRKTLQLFANIRPAVSLHPFTRTLHPNLNLTIIRE 122
>IDH_STAES (Q8CNX4) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 422 Score = 68.9 bits (167), Expect = 9e-12 Identities = 44/126 (34%), Positives = 67/126 (53%), Gaps = 17/126 (13%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYF--------------ETYDVHGDMPAVPPAV 365 + I GDGIGP + A +V++A Y + YD G+ +P Sbjct: 21 IPFIIGDGIGPDIWKAASRVIDAAVEKAYNGEKRIEWKEVLAGQKAYDETGEW--LPQET 78 Query: 366 IESIRRNKVCLKGGLATPVGGGVSSLNMQLRKELDLFASLVNCANVPGLPT---RHKNVD 536 +E+I+ + +KG L TP+GGG+ SLN+ LR+ELDLF L G+P+ R ++VD Sbjct: 79 LETIKEYLIAVKGPLTTPIGGGIRSLNVALRQELDLFTCLRPVRWFKGVPSPVKRPEDVD 138 Query: 537 IVVIRE 554 +V+ RE Sbjct: 139 MVIFRE 144
>IDH_STAEQ (Q5HNL1) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 422 Score = 68.9 bits (167), Expect = 9e-12 Identities = 44/126 (34%), Positives = 67/126 (53%), Gaps = 17/126 (13%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYF--------------ETYDVHGDMPAVPPAV 365 + I GDGIGP + A +V++A Y + YD G+ +P Sbjct: 21 IPFIIGDGIGPDIWKAASRVIDAAVEKAYNGEKRIEWKEVLAGQKAYDETGEW--LPQET 78 Query: 366 IESIRRNKVCLKGGLATPVGGGVSSLNMQLRKELDLFASLVNCANVPGLPT---RHKNVD 536 +E+I+ + +KG L TP+GGG+ SLN+ LR+ELDLF L G+P+ R ++VD Sbjct: 79 LETIKEYLIAVKGPLTTPIGGGIRSLNVALRQELDLFTCLRPVRWFKGVPSPVKRPEDVD 138 Query: 537 IVVIRE 554 +V+ RE Sbjct: 139 MVIFRE 144
>IDH_SYNY3 (P80046) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 475 Score = 68.6 bits (166), Expect = 1e-11 Identities = 44/126 (34%), Positives = 63/126 (50%), Gaps = 17/126 (13%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHAPVY--------FETY------DVHGDMPAVPPAV 365 + I GDG G + A E V+ A A Y F+ Y +++G P Sbjct: 29 IPYIRGDGTGVDIWPATELVINAAIAKAYGGREEINWFKVYAGDEACELYGTYQIFPEDT 88 Query: 366 IESIRRNKVCLKGGLATPVGGGVSSLNMQLRKELDLFASLVNCANVPGLPTRHK---NVD 536 + +I+ V +KG L TPVGGG+ SLN+ LR+ DL+ + C PG P+ HK +D Sbjct: 89 LTAIKEYGVAIKGPLTTPVGGGIRSLNVALRQIFDLYTCVRPCRYYPGTPSPHKTPEKLD 148 Query: 537 IVVIRE 554 I+V RE Sbjct: 149 IIVYRE 154
>IDH_STAAW (Q8NW61) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 422 Score = 67.0 bits (162), Expect = 3e-11 Identities = 42/126 (33%), Positives = 67/126 (53%), Gaps = 17/126 (13%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYF--------------ETYDVHGDMPAVPPAV 365 + I GDGIGP + A +V++A Y + +D G+ +P Sbjct: 21 IPFIIGDGIGPDIWKAASRVIDAAVEKAYNGEKRIEWKEVLAGQKAFDTTGEW--LPQET 78 Query: 366 IESIRRNKVCLKGGLATPVGGGVSSLNMQLRKELDLFASLVNCANVPGLPT---RHKNVD 536 +++I+ + +KG L TP+GGG+ SLN+ LR+ELDLF L G+P+ R ++VD Sbjct: 79 LDTIKEYLIAVKGPLTTPIGGGIRSLNVALRQELDLFTCLRPVRWFKGVPSPVKRPQDVD 138 Query: 537 IVVIRE 554 +V+ RE Sbjct: 139 MVIFRE 144
>IDH_STAAS (Q6G8N2) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 422 Score = 67.0 bits (162), Expect = 3e-11 Identities = 42/126 (33%), Positives = 67/126 (53%), Gaps = 17/126 (13%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYF--------------ETYDVHGDMPAVPPAV 365 + I GDGIGP + A +V++A Y + +D G+ +P Sbjct: 21 IPFIIGDGIGPDIWKAASRVIDAAVEKAYNGEKRIEWKEVLAGQKAFDTTGEW--LPQET 78 Query: 366 IESIRRNKVCLKGGLATPVGGGVSSLNMQLRKELDLFASLVNCANVPGLPT---RHKNVD 536 +++I+ + +KG L TP+GGG+ SLN+ LR+ELDLF L G+P+ R ++VD Sbjct: 79 LDTIKEYLIAVKGPLTTPIGGGIRSLNVALRQELDLFTCLRPVRWFKGVPSPVKRPQDVD 138 Query: 537 IVVIRE 554 +V+ RE Sbjct: 139 MVIFRE 144
>IDH_STAAR (Q6GG12) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 422 Score = 67.0 bits (162), Expect = 3e-11 Identities = 42/126 (33%), Positives = 67/126 (53%), Gaps = 17/126 (13%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYF--------------ETYDVHGDMPAVPPAV 365 + I GDGIGP + A +V++A Y + +D G+ +P Sbjct: 21 IPFIIGDGIGPDIWKAASRVIDAAVEKAYNGEKRIEWKEVLAGQKAFDTTGEW--LPQET 78 Query: 366 IESIRRNKVCLKGGLATPVGGGVSSLNMQLRKELDLFASLVNCANVPGLPT---RHKNVD 536 +++I+ + +KG L TP+GGG+ SLN+ LR+ELDLF L G+P+ R ++VD Sbjct: 79 LDTIKEYLIAVKGPLTTPIGGGIRSLNVALRQELDLFTCLRPVRWFKGVPSPVKRPQDVD 138 Query: 537 IVVIRE 554 +V+ RE Sbjct: 139 MVIFRE 144
>IDH_STAAN (P99167) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 422 Score = 67.0 bits (162), Expect = 3e-11 Identities = 42/126 (33%), Positives = 67/126 (53%), Gaps = 17/126 (13%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYF--------------ETYDVHGDMPAVPPAV 365 + I GDGIGP + A +V++A Y + +D G+ +P Sbjct: 21 IPFIIGDGIGPDIWKAASRVIDAAVEKAYNGEKRIEWKEVLAGQKAFDTTGEW--LPQET 78 Query: 366 IESIRRNKVCLKGGLATPVGGGVSSLNMQLRKELDLFASLVNCANVPGLPT---RHKNVD 536 +++I+ + +KG L TP+GGG+ SLN+ LR+ELDLF L G+P+ R ++VD Sbjct: 79 LDTIKEYLIAVKGPLTTPIGGGIRSLNVALRQELDLFTCLRPVRWFKGVPSPVKRPQDVD 138 Query: 537 IVVIRE 554 +V+ RE Sbjct: 139 MVIFRE 144
>IDH_STAAM (P65099) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 422 Score = 67.0 bits (162), Expect = 3e-11 Identities = 42/126 (33%), Positives = 67/126 (53%), Gaps = 17/126 (13%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYF--------------ETYDVHGDMPAVPPAV 365 + I GDGIGP + A +V++A Y + +D G+ +P Sbjct: 21 IPFIIGDGIGPDIWKAASRVIDAAVEKAYNGEKRIEWKEVLAGQKAFDTTGEW--LPQET 78 Query: 366 IESIRRNKVCLKGGLATPVGGGVSSLNMQLRKELDLFASLVNCANVPGLPT---RHKNVD 536 +++I+ + +KG L TP+GGG+ SLN+ LR+ELDLF L G+P+ R ++VD Sbjct: 79 LDTIKEYLIAVKGPLTTPIGGGIRSLNVALRQELDLFTCLRPVRWFKGVPSPVKRPQDVD 138 Query: 537 IVVIRE 554 +V+ RE Sbjct: 139 MVIFRE 144
>IDH_STAAC (Q5HF79) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 422 Score = 67.0 bits (162), Expect = 3e-11 Identities = 42/126 (33%), Positives = 67/126 (53%), Gaps = 17/126 (13%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYF--------------ETYDVHGDMPAVPPAV 365 + I GDGIGP + A +V++A Y + +D G+ +P Sbjct: 21 IPFIIGDGIGPDIWKAASRVIDAAVEKAYNGEKRIEWKEVLAGQKAFDTTGEW--LPQET 78 Query: 366 IESIRRNKVCLKGGLATPVGGGVSSLNMQLRKELDLFASLVNCANVPGLPT---RHKNVD 536 +++I+ + +KG L TP+GGG+ SLN+ LR+ELDLF L G+P+ R ++VD Sbjct: 79 LDTIKEYLIAVKGPLTTPIGGGIRSLNVALRQELDLFTCLRPVRWFKGVPSPVKRPQDVD 138 Query: 537 IVVIRE 554 +V+ RE Sbjct: 139 MVIFRE 144
>IDH_BACSU (P39126) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 423 Score = 66.6 bits (161), Expect = 4e-11 Identities = 43/126 (34%), Positives = 64/126 (50%), Gaps = 17/126 (13%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYF--------------ETYDVHGDMPAVPPAV 365 + I GDG GP + A +V+EA Y + Y+ G+ +P Sbjct: 22 IPFIEGDGTGPDIWNAASKVLEAAVEKAYKGEKKITWKEVYAGEKAYNKTGEW--LPAET 79 Query: 366 IESIRRNKVCLKGGLATPVGGGVSSLNMQLRKELDLFASLVNCANVPGLPT---RHKNVD 536 ++ IR + +KG L TPVGGG+ SLN+ LR+ELDLF L G+P+ R ++ D Sbjct: 80 LDVIREYFIAIKGPLTTPVGGGIRSLNVALRQELDLFVCLRPVRYFTGVPSPVKRPEDTD 139 Query: 537 IVVIRE 554 +V+ RE Sbjct: 140 MVIFRE 145
>IDH_ECOLI (P08200) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 416 Score = 66.2 bits (160), Expect = 6e-11 Identities = 46/126 (36%), Positives = 65/126 (51%), Gaps = 17/126 (13%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHAPVY--------FETY------DVHGDMPAVPPAV 365 + I GDGIG VT A+ +V++A Y E Y V+G +P Sbjct: 29 IPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERKISWMEIYTGEKSTQVYGQDVWLPAET 88 Query: 366 IESIRRNKVCLKGGLATPVGGGVSSLNMQLRKELDLFASLVNCANVPGLPTRHKN---VD 536 ++ IR +V +KG L TPVGGG+ SLN+ LR+ELDL+ L G P+ K+ D Sbjct: 89 LDLIREYRVAIKGPLTTPVGGGIRSLNVALRQELDLYICLRPVRYYQGTPSPVKHPELTD 148 Query: 537 IVVIRE 554 +V+ RE Sbjct: 149 MVIFRE 154
>IDH_RICTY (Q68XA5) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 483 Score = 62.4 bits (150), Expect = 8e-10 Identities = 38/117 (32%), Positives = 59/117 (50%), Gaps = 7/117 (5%) Frame = +3 Query: 225 PVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHGDM------PAVPPAVIESIRRN 386 P+T+ GDGIGP + AV ++ A + ET +V + + I+R Sbjct: 6 PITIAYGDGIGPEIMDAVLYILRQAEARISLETIEVGEKLYKKHYTSGISEESWNVIQRT 65 Query: 387 KVCLKGGLATPVGGGVSSLNMQLRKELDLFASLVNCANV-PGLPTRHKNVDIVVIRE 554 + LK + TP GG SLN+ +RK L LFA++ + P T H N+++ +IRE Sbjct: 66 GIILKAPITTPQSGGYKSLNVTIRKTLQLFANIRPAVSFHPFTRTLHPNLNLTIIRE 122
>IDH_RICPR (Q9ZDR0) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 483 Score = 62.4 bits (150), Expect = 8e-10 Identities = 38/117 (32%), Positives = 60/117 (51%), Gaps = 7/117 (5%) Frame = +3 Query: 225 PVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHGDM------PAVPPAVIESIRRN 386 P+T+ GDGIGP + AV ++ A + ET +V + + + I+R Sbjct: 6 PITIAYGDGIGPEIMEAVLYILRKAEARISLETIEVGEKLYKKHYTSGISEESWDVIQRT 65 Query: 387 KVCLKGGLATPVGGGVSSLNMQLRKELDLFASLVNCAN-VPGLPTRHKNVDIVVIRE 554 + LK + TP GG SLN+ +RK L LFA++ + P T H N+++ +IRE Sbjct: 66 GIILKAPITTPQSGGYKSLNVTIRKTLQLFANIRPVVSFYPFTRTLHPNLNLTIIRE 122
>IDH_CALNO (P96318) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 429 Score = 60.1 bits (144), Expect = 4e-09 Identities = 43/124 (34%), Positives = 64/124 (51%), Gaps = 15/124 (12%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFET-----YDVHGDMPA-------VPPAVIE 371 V GDGIGP + + ++V++A Y T ++V A +P ++ Sbjct: 35 VAYFKGDGIGPEIVESAKKVLDAAVDKAYGGTRRIVWWEVTAGEEAQKECGSLLPDGTLQ 94 Query: 372 SIRRNKVCLKGGLATPVGGGVSSLNMQLRKELDLFASLVNCANVPGLPTRH---KNVDIV 542 + + +V LKG L TPVGGG SLN+ LR LDL+++ V G PT H +N+D V Sbjct: 95 AFKLARVNLKGPLTTPVGGGFRSLNVTLRMVLDLYSN-VRPVKWYGQPTPHCHPENIDWV 153 Query: 543 VIRE 554 + RE Sbjct: 154 IFRE 157
>IDH1_COLMA (P41560) Isocitrate dehydrogenase [NADP] 1 (EC 1.1.1.42)| (Oxalosuccinate decarboxylase 1) (IDH-I) (NADP(+)-specific ICDH 1) (IDP-1) Length = 414 Score = 59.3 bits (142), Expect = 7e-09 Identities = 43/126 (34%), Positives = 63/126 (50%), Gaps = 17/126 (13%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHAPVY-----FETYDVHGDMPA---------VPPAV 365 + I GDGIG VT + +V+ A A Y E +V+ A +P Sbjct: 28 IPYIEGDGIGVDVTPPMLKVVNAAVAKAYGGDRKIEWLEVYAGEKATKMYDSETWLPEET 87 Query: 366 IESIRRNKVCLKGGLATPVGGGVSSLNMQLRKELDLFASLVNCANVPGLPT---RHKNVD 536 + ++ KV +KG L TPVGGG+SSLN+ +R+ LDL+ G+P+ R VD Sbjct: 88 LNILQEYKVSIKGPLTTPVGGGMSSLNVAIRQMLDLYVCQRPVQWFTGVPSPVKRPSEVD 147 Query: 537 IVVIRE 554 +V+ RE Sbjct: 148 MVIFRE 153
>IDH_ARCFU (O29610) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 412 Score = 58.5 bits (140), Expect = 1e-08 Identities = 41/118 (34%), Positives = 66/118 (55%), Gaps = 14/118 (11%) Frame = +3 Query: 243 GDGIGPLVTGAVEQVMEAM-----HAPVYFETY------DVHGDMPAVPPAVIESIRRNK 389 GDGIG V A +V++A V+F+ Y ++G+ +P + +I+ + Sbjct: 35 GDGIGKDVVPAAIRVLDAAADKIGKEVVWFQVYAGEDAYKLYGNY--LPDDTLNAIKEFR 92 Query: 390 VCLKGGLATPVGGGVSSLNMQLRKELDLFASLVNCANVPGLPTRHKN---VDIVVIRE 554 V LKG L TPVGGG SLN+ +R+ LDL+A++ + G+P+ K+ V+ V+ RE Sbjct: 93 VALKGPLTTPVGGGYRSLNVTIRQVLDLYANVRPVYYLKGVPSPIKHPEKVNFVIFRE 150
>IDH_STRMU (Q59940) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 393 Score = 55.8 bits (133), Expect = 8e-08 Identities = 40/126 (31%), Positives = 63/126 (50%), Gaps = 17/126 (13%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYF--------------ETYDVHGDMPAVPPAV 365 + I GDG+G + + V + A VY + Y+ G+ +P Sbjct: 20 IPYIEGDGVGQDIWKNAQIVFDKAIAKVYGGHKQVIWREVLAGKKAYNETGNW--LPNET 77 Query: 366 IESIRRNKVCLKGGLATPVGGGVSSLNMQLRKELDLFASLVNCANVPGLPTRHKNVD--- 536 +E I+ + + +KG L TPVGGG+ SLN+ LR+ELDLFA + G+P+ K+ + Sbjct: 78 LEIIKTHLLAIKGPLETPVGGGIRSLNVALRQELDLFACVRPVRYFKGVPSPLKHPEKTA 137 Query: 537 IVVIRE 554 I + RE Sbjct: 138 ITIFRE 143
>IDH_STRSL (Q59985) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 391 Score = 55.8 bits (133), Expect = 8e-08 Identities = 37/98 (37%), Positives = 51/98 (52%), Gaps = 14/98 (14%) Frame = +3 Query: 228 VTLIPGDGIG--------PLVTGAVEQVMEAMHAPVYFE------TYDVHGDMPAVPPAV 365 + I GDG+G + AVE E + E YD G+ +P Sbjct: 20 IPFIEGDGVGHDIWKNAQAIFDKAVEVAYEGKRHIEWQELLAGKKAYDKTGEW--LPKET 77 Query: 366 IESIRRNKVCLKGGLATPVGGGVSSLNMQLRKELDLFA 479 +E+IR + V +KG L TPVGGG+ SLN+ LR+ELDL+A Sbjct: 78 LEAIRESLVAIKGPLETPVGGGIRSLNVALRQELDLYA 115
>LEU3_SULTO (P50455) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 336 Score = 55.5 bits (132), Expect = 1e-07 Identities = 35/119 (29%), Positives = 65/119 (54%), Gaps = 10/119 (8%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVM----EAMHAPVYFETYDVHGDMP------AVPPAVIESI 377 V LI GDGIGP + ++++ E P+ + + GD A+P ++ I Sbjct: 4 VALIQGDGIGPEIVSKSKRILAKINELYSLPIEYIEVEA-GDRALARYGEALPKDSLKII 62 Query: 378 RRNKVCLKGGLATPVGGGVSSLNMQLRKELDLFASLVNCANVPGLPTRHKNVDIVVIRE 554 + + LKG PVG + + ++LR+ D++A++ ++PG+ T++ NVDI+++RE Sbjct: 63 DKADIILKG----PVGESAADVVVKLRQIYDMYANIRPAKSIPGIDTKYGNVDILIVRE 117
>IDH_HELPJ (Q9ZN36) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 425 Score = 55.1 bits (131), Expect = 1e-07 Identities = 39/132 (29%), Positives = 63/132 (47%), Gaps = 23/132 (17%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHAPVY-----------------FETYDVHGDMPA-- 350 + I GDGIG +T A+ +V+++ Y ++ + H ++ Sbjct: 32 IPFIEGDGIGSDITPAMIKVVDSAVQKAYKGEKKIAWYEVFVGEKCYQKFKDHKELSPEE 91 Query: 351 --VPPAVIESIRRNKVCLKGGLATPVGGGVSSLNMQLRKELDLFASL--VNCANVPGLPT 518 + P IE+I KV +KG L TP+G G SLN+ LR+++DL+ L V P Sbjct: 92 QWLLPDTIEAINHYKVSIKGPLTTPIGEGFRSLNVALRQKMDLYVCLRPVRWYGSPSPVK 151 Query: 519 RHKNVDIVVIRE 554 + VD+V+ RE Sbjct: 152 EPQKVDMVIFRE 163
>IDH_HELPY (P56063) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 425 Score = 54.3 bits (129), Expect = 2e-07 Identities = 40/132 (30%), Positives = 63/132 (47%), Gaps = 23/132 (17%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHAPVY--------------------FETY-DVHGDM 344 + I GDGIG +T A+ +V+++ Y F+ Y ++ + Sbjct: 32 IPFIEGDGIGSDITPAMIKVVDSAVQKAYKGEKKIAWYEVFVGEKCYQKFKDYKELSPEE 91 Query: 345 PAVPPAVIESIRRNKVCLKGGLATPVGGGVSSLNMQLRKELDLFASL--VNCANVPGLPT 518 + P IE+I KV +KG L TP+G G SLN+ LR+++DL+ L V P Sbjct: 92 QWLLPDTIEAINHYKVSIKGPLTTPIGEGFRSLNVALRQKMDLYVCLRPVRWYGSPSPVK 151 Query: 519 RHKNVDIVVIRE 554 + VD+V+ RE Sbjct: 152 EPQKVDMVIFRE 163
>LEU3_ARCFU (O29627) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 326 Score = 53.9 bits (128), Expect = 3e-07 Identities = 33/116 (28%), Positives = 58/116 (50%), Gaps = 5/116 (4%) Frame = +3 Query: 222 RPVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHGDM-----PAVPPAVIESIRRN 386 + + +IPGDGIG V A ++E + P + YD + A+P +E+ R++ Sbjct: 2 KKIVVIPGDGIGKEVMEAAMLILEKLDLPFEYSYYDAGDEALEKYGKALPDETLEACRKS 61 Query: 387 KVCLKGGLATPVGGGVSSLNMQLRKELDLFASLVNCANVPGLPTRHKNVDIVVIRE 554 L G G + + ++LR+EL FA++ + G+ + +DIVV+RE Sbjct: 62 DAVLFGA----AGETAADVIVRLRRELGTFANVRPAKAIEGIECLYPGLDIVVVRE 113
>LEU3_METTH (O27441) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 329 Score = 53.5 bits (127), Expect = 4e-07 Identities = 34/115 (29%), Positives = 59/115 (51%), Gaps = 6/115 (5%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHGDM------PAVPPAVIESIRRNK 389 + +IPGDGIG V A ++ + + F D GD A+P +E++ + Sbjct: 6 IAVIPGDGIGVEVMEAALHILNTLDLDLEFIHADA-GDACLKRTGTALPEETLEAVGEAR 64 Query: 390 VCLKGGLATPVGGGVSSLNMQLRKELDLFASLVNCANVPGLPTRHKNVDIVVIRE 554 L G G + + ++LR+E DLFA+L ++PG+P + ++D V++RE Sbjct: 65 ATLFGA----AGESAADVIVRLRREFDLFANLRPVKSLPGVPCLYPDLDFVIVRE 115
>LEU3_SULSO (Q9UXB2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 336 Score = 50.1 bits (118), Expect = 4e-06 Identities = 32/123 (26%), Positives = 64/123 (52%), Gaps = 14/123 (11%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHGDM--------------PAVPPAV 365 V +IPGDGIGP + ++++ + E Y++ D+ A+P Sbjct: 5 VAVIPGDGIGPELYEGSKRIIAKL-----IEKYNLDIDLIEVEAGDVALNKYGEALPRHT 59 Query: 366 IESIRRNKVCLKGGLATPVGGGVSSLNMQLRKELDLFASLVNCANVPGLPTRHKNVDIVV 545 ++ I + + LKG PVG + ++LR+ D++A++ ++P + +++ NVD+V+ Sbjct: 60 LDVIEKADMILKG----PVGETAMDVVVKLRQMYDMYANIRPAKSLPNVQSKYPNVDLVI 115 Query: 546 IRE 554 +RE Sbjct: 116 VRE 118
>LEU3_MYCTU (P95313) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 336 Score = 50.1 bits (118), Expect = 4e-06 Identities = 38/120 (31%), Positives = 60/120 (50%), Gaps = 11/120 (9%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDV-----HGDMPAVPPAVIESIRRNKV 392 + +I GDGIGP VT +V++A+ V +YD+ H +P +V+ +R + Sbjct: 3 LAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNHDA 62 Query: 393 CLKGGLATP-VGGGV--SSLNMQLRKELDLFASLVNCANVPGLP---TRHKNVDIVVIRE 554 L G + P V GV L ++LR ELD +L PG+ + + +D VV+RE Sbjct: 63 ILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVVVRE 122
>LEU3_MYCBO (P94929) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 336 Score = 50.1 bits (118), Expect = 4e-06 Identities = 38/120 (31%), Positives = 60/120 (50%), Gaps = 11/120 (9%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDV-----HGDMPAVPPAVIESIRRNKV 392 + +I GDGIGP VT +V++A+ V +YD+ H +P +V+ +R + Sbjct: 3 LAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNHDA 62 Query: 393 CLKGGLATP-VGGGV--SSLNMQLRKELDLFASLVNCANVPGLP---TRHKNVDIVVIRE 554 L G + P V GV L ++LR ELD +L PG+ + + +D VV+RE Sbjct: 63 ILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVVVRE 122
>IDH_AQUAE (O67480) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 426 Score = 48.1 bits (113), Expect = 2e-05 Identities = 39/124 (31%), Positives = 58/124 (46%), Gaps = 15/124 (12%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVH------GDMPA------VPPAVIE 371 + I GDGIGP +T A+ ++ Y + ++ GD +P ++ Sbjct: 41 IPFIEGDGIGPEITQAMLLIINTAVEKTYNGSKKIYWVELLAGDKAEEKTGERLPQETLD 100 Query: 372 SIRRNKVCLKGGLATPVGGGVSSLNMQLRKELDLFASLVNCANVPGLPTRHKN---VDIV 542 ++ + V +KG L TPVG GV S+N LR+ D + S V G T N VD+V Sbjct: 101 VLKESIVGIKGPLGTPVGKGVRSINSALRRAFDYY-SAVRPVYWMGQATPIPNPERVDLV 159 Query: 543 VIRE 554 V RE Sbjct: 160 VFRE 163
>LEU3_MYCPA (Q73VI1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 336 Score = 47.4 bits (111), Expect = 3e-05 Identities = 39/120 (32%), Positives = 61/120 (50%), Gaps = 11/120 (9%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDV-----HGDMPAVPPAVIESIRRNKV 392 + +I GDGIGP VT +V++A+ V YD+ H +P +VI+ +R + Sbjct: 3 LAVIGGDGIGPEVTAEALKVLDAVLPGVDKTEYDLGARRYHATGELLPDSVIDELRAHDA 62 Query: 393 CLKGGLATP-VGGGV--SSLNMQLRKELDLFASLVNCANVPGLPT---RHKNVDIVVIRE 554 L G + P V GV L ++LR ELD +L PG+ + + ++D VV+RE Sbjct: 63 ILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPGRLYPGVSSPLAGNPDIDFVVVRE 122
>LEU3_AGRT5 (P24404) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 370 Score = 46.2 bits (108), Expect = 6e-05 Identities = 41/137 (29%), Positives = 62/137 (45%), Gaps = 24/137 (17%) Frame = +3 Query: 216 TPRPVTLIPGDGIGPLVTGAVEQVMEAMHAP-----------VYFETYDVHGDMPAVPPA 362 T R + L+PGDGIGP V +++E M++ V YD HG A+ A Sbjct: 2 TVRSLFLLPGDGIGPEAMTEVRKLIEYMNSAHNAGFTVSEGLVGGSAYDAHG--VAISDA 59 Query: 363 VIESIRRNKVCLKGGLATPVGGGVSSLN------MQLRKELDLFASLVNCANVPGL---- 512 +E L G + P GV + ++LRK+L+LFA+L P L Sbjct: 60 DMEKALAADAILFGAVGGPKWDGVPYEHRPEAGLLRLRKDLELFANLRPAICYPALAAAS 119 Query: 513 ---PTRHKNVDIVVIRE 554 P + +DI+++RE Sbjct: 120 SLKPELVEGLDILIVRE 136
>LEU3_PHACH (O59930) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 380 Score = 45.1 bits (105), Expect = 1e-04 Identities = 41/132 (31%), Positives = 62/132 (46%), Gaps = 23/132 (17%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHA-----PVYFETYDVHG---DMPAVP--PAVIESI 377 + ++PGDGIGP V +V+E + A + ET+D G D P A +E+ Sbjct: 8 IVILPGDGIGPEVVAEATRVLEVVSASSSDVEIKLETHDFGGCSIDKHGEPLTAATLEAC 67 Query: 378 RRNKVCLKGGLATPVGGGVSSLN-----MQLRKELDLFASL--VNCAN------VPGLPT 518 + L G + P G S + + LRK L L+A++ N A+ P P+ Sbjct: 68 KLADAILLGAIGGPKWGVNSKVRPEQALLALRKALGLYANIRPANFASDSLLAYSPLKPS 127 Query: 519 RHKNVDIVVIRE 554 + VDI+VIRE Sbjct: 128 VARGVDIIVIRE 139
>LEU3_MYCLE (O33117) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 336 Score = 45.1 bits (105), Expect = 1e-04 Identities = 37/120 (30%), Positives = 57/120 (47%), Gaps = 11/120 (9%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDV-----HGDMPAVPPAVIESIRRNKV 392 + +I GDGIGP V ++++ + V TYD+ H +P +V+ +R + Sbjct: 3 LAIIGGDGIGPEVVAQAVKILDVVLPGVQKTTYDLGARRYHTTGELLPESVLAELREHDA 62 Query: 393 CLKGGLATP-VGGGV--SSLNMQLRKELDLFASLVNCANVPG---LPTRHKNVDIVVIRE 554 L G + P V GV L ++LR ELD +L PG L ++D VV+RE Sbjct: 63 ILLGAVGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVNSLLAGKPDIDFVVVRE 122
>LYS12_YEAST (P40495) Homoisocitrate dehydrogenase, mitochondrial precursor (EC| 1.1.1.87) Length = 371 Score = 43.5 bits (101), Expect = 4e-04 Identities = 37/123 (30%), Positives = 64/123 (52%), Gaps = 14/123 (11%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHAP-----------VYFETYDVHGDMPAVPPAVIES 374 + LIPGDGIG V A +QV+E +++ F+T+ G A+P ++ Sbjct: 26 IGLIPGDGIGKEVIPAGKQVLENLNSKHGLSFNFIDLYAGFQTFQETG--KALPDETVKV 83 Query: 375 IRRN-KVCLKGGLATPVG--GGVSSLNMQLRKELDLFASLVNCANVPGLPTRHKNVDIVV 545 ++ + L G + +P G SS + LR+E+ LFA++ +V G + K +D+V+ Sbjct: 84 LKEQCQGALFGAVQSPTTKVEGYSSPIVALRREMGLFANVRPVKSVEG--EKGKPIDMVI 141 Query: 546 IRE 554 +RE Sbjct: 142 VRE 144
>LEU3_THIDA (Q3SHL3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 353 Score = 43.1 bits (100), Expect = 5e-04 Identities = 36/132 (27%), Positives = 59/132 (44%), Gaps = 23/132 (17%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMH----------APVYFETYDVHGDMPAVPPAVIESI 377 + ++PGDGIGP + +V+EA+ AP+ YD GD +P A ++ Sbjct: 3 IAVLPGDGIGPEIISQAVKVLEALKSEGAKIEMETAPIGGAGYDAAGD--PLPEATLKLA 60 Query: 378 RRNKVCLKGGLATPVGGGVSSL------NMQLRKELDLFASLVNCANVPGL-------PT 518 R L G + P + +++RKEL+LFA+L P L P Sbjct: 61 READAVLLGAVGGPQYDTLDRPLRPERGLLRIRKELNLFANLRPALLYPELASASSLKPE 120 Query: 519 RHKNVDIVVIRE 554 +D++++RE Sbjct: 121 VVSGLDLMIVRE 132
>LEU3_THEFY (Q47SB4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 354 Score = 42.7 bits (99), Expect = 7e-04 Identities = 40/128 (31%), Positives = 61/128 (47%), Gaps = 19/128 (14%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDV----------HGDMPAVPPAVIESI 377 + +IPGDGIGP V +V+ A+ AP + T D H +P AV E + Sbjct: 8 LAVIPGDGIGPEVVAEGLKVLSAV-APRHGLTLDTTEYELGAQRWHATGEVLPDAVEEEL 66 Query: 378 RRNKVCLKGGLATP-VGGGVSSLNMQLRKELDLFASLVNCANV---PGLPT-----RHKN 530 R++ L G + P V GV + LR + F+ VN V PG+ T ++ Sbjct: 67 RQHDAILLGAVGDPTVPSGVLERGLLLRLRFN-FSHYVNLRPVRLYPGVTTPLAGVAPED 125 Query: 531 VDIVVIRE 554 +D++V+RE Sbjct: 126 IDMLVVRE 133
>LEU3_DEIRA (Q9RTH9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 352 Score = 42.4 bits (98), Expect = 9e-04 Identities = 44/139 (31%), Positives = 61/139 (43%), Gaps = 27/139 (19%) Frame = +3 Query: 219 PRPVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFE-------TYDVHGDMPAVPPAVIESI 377 P+ +TL PGDGIGP VT A QV+ + V E YD HG+ P + +++ Sbjct: 2 PKVITL-PGDGIGPEVTAAAVQVLREVAPDVTVEEHAIGGGAYDAHGE--PFPTSTRDAL 58 Query: 378 RRNKVCLKGGLATPVGGGVSSLNMQ-------------LRKELDLFASLVNCANVPGL-- 512 + L G VGG S Q LRK L +A+L PGL Sbjct: 59 KEADAVLLG----TVGGAHDSAWNQLPRHLRPESGLLALRKALGCYANLRPVRVQPGLEH 114 Query: 513 --PTR---HKNVDIVVIRE 554 P + + VDI+++RE Sbjct: 115 LSPLKAELARGVDILIVRE 133
>LEU3_CHRVO (Q7NUC2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 354 Score = 42.4 bits (98), Expect = 9e-04 Identities = 36/132 (27%), Positives = 57/132 (43%), Gaps = 23/132 (17%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAM----------HAPVYFETYDVHGDMPAVPPAVIESI 377 + ++PGDGIGP + E+V+E + HAP+ YD +G P A + Sbjct: 3 IAILPGDGIGPEIIAQAERVLEVLRRDGLKIETEHAPLGGAAYDQYG--VPYPEATQKLA 60 Query: 378 RRNKVCLKGGLATPVGGGVSSL------NMQLRKELDLFASLVNCANVPGL-------PT 518 R L G + P + + +RK+L+LFA+L P L P Sbjct: 61 READAVLLGAVGGPAYDKLDRPLRPERGLLAIRKDLNLFANLRPAILYPELANASTLKPE 120 Query: 519 RHKNVDIVVIRE 554 +DI+++RE Sbjct: 121 VVAGLDIMIVRE 132
>LEU3_BORPE (Q7VY73) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 358 Score = 42.0 bits (97), Expect = 0.001 Identities = 36/127 (28%), Positives = 55/127 (43%), Gaps = 18/127 (14%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHGDM-----PAVPPAVIESIRRNKV 392 + ++PGDGIGP + E+V++A+ P+ V G +PPA +E + + Sbjct: 5 IAVLPGDGIGPEIVEQAERVLKALDLPLELRQAPVGGAAFDQFEHPLPPATLELAQGSHA 64 Query: 393 CLKGGL------ATPVGGGVSSLNMQLRKELDLFASLVNCANVPGL-------PTRHKNV 533 L G + P + LRK L LFA+L P L P + Sbjct: 65 VLFGAVGDWKYDTLPREFRPEQAILGLRKALGLFANLRPAILYPELASASSLKPEIVSGL 124 Query: 534 DIVVIRE 554 DI++IRE Sbjct: 125 DILIIRE 131
>LEU3_BORPA (Q7W929) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 358 Score = 42.0 bits (97), Expect = 0.001 Identities = 36/127 (28%), Positives = 55/127 (43%), Gaps = 18/127 (14%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHGDM-----PAVPPAVIESIRRNKV 392 + ++PGDGIGP + E+V++A+ P+ V G +PPA +E + + Sbjct: 5 IAVLPGDGIGPEIVEQAERVLKALDLPLELRQAPVGGAAFDQFEHPLPPATLELAQGSHA 64 Query: 393 CLKGGL------ATPVGGGVSSLNMQLRKELDLFASLVNCANVPGL-------PTRHKNV 533 L G + P + LRK L LFA+L P L P + Sbjct: 65 VLFGAVGDWKYDTLPREFRPEQAILGLRKALGLFANLRPAILYPELASASSLKPEIVSGL 124 Query: 534 DIVVIRE 554 DI++IRE Sbjct: 125 DILIIRE 131
>LEU3_BORBR (Q7WKH4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 358 Score = 42.0 bits (97), Expect = 0.001 Identities = 36/127 (28%), Positives = 55/127 (43%), Gaps = 18/127 (14%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHGDM-----PAVPPAVIESIRRNKV 392 + ++PGDGIGP + E+V++A+ P+ V G +PPA +E + + Sbjct: 5 IAVLPGDGIGPEIVEQAERVLKALDLPLELRQAPVGGAAFDQFEHPLPPATLELAQGSHA 64 Query: 393 CLKGGL------ATPVGGGVSSLNMQLRKELDLFASLVNCANVPGL-------PTRHKNV 533 L G + P + LRK L LFA+L P L P + Sbjct: 65 VLFGAVGDWKYDTLPREFRPEQAILGLRKALGLFANLRPAILYPELASASSLKPEIVSGL 124 Query: 534 DIVVIRE 554 DI++IRE Sbjct: 125 DILIIRE 131
>LEU3_PROMT (Q46LE2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 359 Score = 41.6 bits (96), Expect = 0.002 Identities = 32/131 (24%), Positives = 53/131 (40%), Gaps = 22/131 (16%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFET---------YDVHGDMPAVPPAVIESIR 380 +TL+PGDGIGP +T ++++ + FE + D P ++ + Sbjct: 6 ITLLPGDGIGPEITNVTHKILDLVSRKFGFEIKFKEMPFGGSAIDSDGIPFPDRTLQECK 65 Query: 381 RNKVCLKGGLATPVGGGVSSLN------MQLRKELDLFASLVNCANVPGLPTRH------ 524 + L + P + + LR LDLFA++ +P L Sbjct: 66 NSDAVLLAAIGDPKYDELPREKRPETGLLNLRSSLDLFANIRPVKIIPSLTKASSLKEDF 125 Query: 525 -KNVDIVVIRE 554 K VD+VV+RE Sbjct: 126 VKEVDLVVVRE 136
>LEU3_THEAQ (P24098) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 344 Score = 41.6 bits (96), Expect = 0.002 Identities = 37/131 (28%), Positives = 60/131 (45%), Gaps = 22/131 (16%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMH----APVYFETYD-----VHGDMPAVPPAVIESIR 380 V ++PGDGIGP VT A +V++A+ + +ET+ + G P + + Sbjct: 3 VAVLPGDGIGPEVTEAALRVLKALDEREGLGLTYETFPFGGAAIDGYGEPFPEVTRKGVE 62 Query: 381 RNKVCLKGGLATPVGGGV------SSLNMQLRKELDLFASLVNCANVPGL----PTRH-- 524 + L G + P + S + LRK DLFA+L PGL P + Sbjct: 63 AAEAVLLGSVGGPKWDALPRKIRPESGLLALRKSQDLFANLRPAKVFPGLERLSPLKEEI 122 Query: 525 -KNVDIVVIRE 554 + VD++++RE Sbjct: 123 ARGVDVLIVRE 133
>LEU3_STRR6 (Q8DPJ4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 345 Score = 41.2 bits (95), Expect = 0.002 Identities = 36/131 (27%), Positives = 57/131 (43%), Gaps = 20/131 (15%) Frame = +3 Query: 222 RPVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFE---------TYDVHGDMPAVPPAVIES 374 + + + GDGIGP + A +V+EA+ F+ D+ P +P +++ Sbjct: 3 KKIVALVGDGIGPEIMEAGLEVLEALAEKTGFDYEIDRRPFGGADIDAAGPPLPDETLKA 62 Query: 375 IRRNKVCLKGGLATPVGGGVSSLN----MQLRKELDLFASLVNCANVPGL-------PTR 521 R L + +P GV+ M LRKEL+L+A++ L P R Sbjct: 63 SREADAILLVAIGSPQYDGVAVRPEQGLMALRKELNLYANIRPVKIFDSLKYLSPLKPER 122 Query: 522 HKNVDIVVIRE 554 VD VV+RE Sbjct: 123 ISGVDFVVVRE 133
>LEU3_BRUSU (Q8FVF3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 370 Score = 40.8 bits (94), Expect = 0.003 Identities = 38/135 (28%), Positives = 61/135 (45%), Gaps = 24/135 (17%) Frame = +3 Query: 222 RPVTLIPGDGIGPLVTGAVEQVMEAMHAPVY--FET---------YDVHGDMPAVPPAVI 368 R + L+PGDGIGP V +V+ +++ + FET YD HG A+ A + Sbjct: 4 RKLLLLPGDGIGPEAMAEVRKVIAFLNSDLNLGFETEEGLVGGCAYDAHGQ--AISDADM 61 Query: 369 ESIRRNKVCLKGGLATPVGGGV------SSLNMQLRKELDLFASLVNCANVPGL------ 512 E L G + P V + ++LRK++ L+A+L P L Sbjct: 62 EKALAADAVLFGAVGGPKWDSVPYEVRPEAGLLRLRKDMQLYANLRPAICYPALAHSSSL 121 Query: 513 -PTRHKNVDIVVIRE 554 P + +DI+++RE Sbjct: 122 KPEVIEGLDILILRE 136
>LEU3_NOCFA (Q5YRX2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 335 Score = 40.4 bits (93), Expect = 0.003 Identities = 35/120 (29%), Positives = 56/120 (46%), Gaps = 11/120 (9%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDV-----HGDMPAVPPAVIESIRRNKV 392 + +IPGDGIGP V +V++ + V YD+ H +P +V+ +R + Sbjct: 3 LAVIPGDGIGPEVIAEALKVLDVVVPGVEKTEYDLGAKRYHATGEILPDSVLPELREHDA 62 Query: 393 CLKGGLATP-VGGGV--SSLNMQLRKELDLFASLVNCANVPGLPT---RHKNVDIVVIRE 554 L G + P V GV L ++ R ELD +L G+ + ++D VV+RE Sbjct: 63 ILLGAIGDPSVPSGVLERGLLLRTRFELDHHVNLRPSRLFTGVRSPLAGAPDIDFVVVRE 122
>LEU3_BRUME (Q8YCX4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 370 Score = 40.4 bits (93), Expect = 0.003 Identities = 38/135 (28%), Positives = 60/135 (44%), Gaps = 24/135 (17%) Frame = +3 Query: 222 RPVTLIPGDGIGPLVTGAVEQVMEAMHAPVY--FET---------YDVHGDMPAVPPAVI 368 R + L+PGDGIGP V +V+ +++ + FET YD HG A+ A + Sbjct: 4 RKLLLLPGDGIGPEAMAEVRKVIAFLNSDLNLGFETEEGLVGGCAYDAHGQ--AISDADM 61 Query: 369 ESIRRNKVCLKGGLATPVGGGV------SSLNMQLRKELDLFASLVNCANVPGL------ 512 E L G + P V ++LRK++ L+A+L P L Sbjct: 62 EKALAADAVLFGAVGGPKWDSVPYEVRPEGGLLRLRKDMQLYANLRPAICYPALAHSSSL 121 Query: 513 -PTRHKNVDIVVIRE 554 P + +DI+++RE Sbjct: 122 KPEVIEGLDILILRE 136
>LEU3_ACIAD (Q6FEV6) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 359 Score = 40.4 bits (93), Expect = 0.003 Identities = 35/135 (25%), Positives = 58/135 (42%), Gaps = 24/135 (17%) Frame = +3 Query: 222 RPVTLIPGDGIGPLVTGAVEQVMEAM-----------HAPVYFETYDVHGDMPAVPPAVI 368 + + ++ GDGIGP + GA EQV+ + H + D HG+ P Sbjct: 3 KQILILAGDGIGPEIVGAAEQVLTKVNEKFELGLTWEHGLLGGSAIDAHGE--PYPAVTS 60 Query: 369 ESIRRNKVCLKGGLATPVGGGVS-SLN-----MQLRKELDLFASLVNCANVPGL------ 512 E ++ L G + P + S+ +++R EL+LFA+L P L Sbjct: 61 EQAKKADAILLGAVGGPKWDTIERSIRPERGLLKIRSELNLFANLRPALLYPQLADASSL 120 Query: 513 -PTRHKNVDIVVIRE 554 P +DI+++RE Sbjct: 121 KPEIVAGLDILIVRE 135
>LEU3_THETH (P61495) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 345 Score = 40.4 bits (93), Expect = 0.003 Identities = 36/131 (27%), Positives = 58/131 (44%), Gaps = 22/131 (16%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHAP----VYFETYDVHGDM-----PAVPPAVIESIR 380 V ++PGDGIGP VT A +V+ A+ + +E + G P + + Sbjct: 3 VAVLPGDGIGPEVTEAALKVLRALDEAEGLGLAYEVFPFGGAAIDAFGEPFPEPTRKGVE 62 Query: 381 RNKVCLKGGLATPVGGGV------SSLNMQLRKELDLFASLVNCANVPGL----PTRH-- 524 + L G + P G+ + + LRK DLFA+L PGL P + Sbjct: 63 EAEAVLLGSVGGPKWDGLPRKISPETGLLSLRKSQDLFANLRPAKVFPGLERLSPLKEEI 122 Query: 525 -KNVDIVVIRE 554 + VD++++RE Sbjct: 123 ARGVDVLIVRE 133
>LEU3_THET8 (Q5SIY4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 345 Score = 40.4 bits (93), Expect = 0.003 Identities = 36/131 (27%), Positives = 58/131 (44%), Gaps = 22/131 (16%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHAP----VYFETYDVHGDM-----PAVPPAVIESIR 380 V ++PGDGIGP VT A +V+ A+ + +E + G P + + Sbjct: 3 VAVLPGDGIGPEVTEAALKVLRALDEAEGLGLAYEVFPFGGAAIDAFGEPFPEPTRKGVE 62 Query: 381 RNKVCLKGGLATPVGGGV------SSLNMQLRKELDLFASLVNCANVPGL----PTRH-- 524 + L G + P G+ + + LRK DLFA+L PGL P + Sbjct: 63 EAEAVLLGSVGGPKWDGLPRKIRPETGLLSLRKSQDLFANLRPAKVFPGLERLSPLKEEI 122 Query: 525 -KNVDIVVIRE 554 + VD++++RE Sbjct: 123 ARGVDVLIVRE 133
>LEU3_THET2 (P61494) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 345 Score = 40.4 bits (93), Expect = 0.003 Identities = 36/131 (27%), Positives = 58/131 (44%), Gaps = 22/131 (16%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHAP----VYFETYDVHGDM-----PAVPPAVIESIR 380 V ++PGDGIGP VT A +V+ A+ + +E + G P + + Sbjct: 3 VAVLPGDGIGPEVTEAALKVLRALDEAEGLGLAYEVFPFGGAAIDAFGEPFPEPTRKGVE 62 Query: 381 RNKVCLKGGLATPVGGGV------SSLNMQLRKELDLFASLVNCANVPGL----PTRH-- 524 + L G + P G+ + + LRK DLFA+L PGL P + Sbjct: 63 EAEAVLLGSVGGPKWDGLPRKIRPETGLLSLRKSQDLFANLRPAKVFPGLERLSPLKEEI 122 Query: 525 -KNVDIVVIRE 554 + VD++++RE Sbjct: 123 ARGVDVLIVRE 133
>LEU3_RHIME (Q92KY8) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 370 Score = 40.0 bits (92), Expect = 0.004 Identities = 38/137 (27%), Positives = 58/137 (42%), Gaps = 24/137 (17%) Frame = +3 Query: 216 TPRPVTLIPGDGIGPLVTGAVEQVMEAMHAP-----------VYFETYDVHGDMPAVPPA 362 T R + L+PGDGIGP V +++ M+A V YD HG A+ Sbjct: 2 TVRNLFLLPGDGIGPEAMAEVRKIIAYMNAERDAGFVTDEGLVGGSAYDAHG--AAISEG 59 Query: 363 VIESIRRNKVCLKGGLATPVGGGV------SSLNMQLRKELDLFASLVNCANVPGL---- 512 + L G + P V + ++LRK+L+LFA+L P L Sbjct: 60 DMAKALAADAVLFGAVGGPKWDAVPYEVRPEAGLLRLRKDLELFANLRPAICYPALANAS 119 Query: 513 ---PTRHKNVDIVVIRE 554 P + +DI+++RE Sbjct: 120 SLKPELVEGLDILIVRE 136
>IDH3A_PIG (P56471) Isocitrate dehydrogenase [NAD] subunit alpha,| mitochondrial (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) (Fragments) Length = 90 Score = 39.7 bits (91), Expect = 0.006 Identities = 17/33 (51%), Positives = 24/33 (72%) Frame = +3 Query: 213 GTPRPVTLIPGDGIGPLVTGAVEQVMEAMHAPV 311 G + VTLIPGDGIGP ++ AV ++ +A AP+ Sbjct: 2 GGVKTVTLIPGDGIGPEISAAVMKIFDAAKAPI 34
>LEU3_LACLA (Q02143) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 345 Score = 39.3 bits (90), Expect = 0.008 Identities = 36/131 (27%), Positives = 57/131 (43%), Gaps = 20/131 (15%) Frame = +3 Query: 222 RPVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFE-----------TYDVHGDMPAVPPAVI 368 + + + GDGIGP + A V++A+ + FE D HG +P + Sbjct: 3 KKIVTLAGDGIGPEIMSAGLSVLKAVSKKIDFEYELEAKDFGGIAIDKHGH--PLPEETL 60 Query: 369 ESIRRNKVCLKGGLATPVGGGVSSLNMQ----LRKELDLFASLVNCANVPGL----PTRH 524 ++++ L + P Q LRKEL L+A++ P L P R+ Sbjct: 61 QAVKNADAILLAAIGHPKYNNAKVRPEQGLLALRKELGLYANVRPLKIYPALKKLSPIRN 120 Query: 525 -KNVDIVVIRE 554 +NVD +VIRE Sbjct: 121 VENVDFLVIRE 131
>DLPA_LEGPH (Q48806) Protein dlpA| Length = 615 Score = 38.5 bits (88), Expect = 0.013 Identities = 34/132 (25%), Positives = 56/132 (42%), Gaps = 20/132 (15%) Frame = +3 Query: 219 PRPVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHGDM-----PAVPPAVIESIRR 383 P + ++PGDGIG VT A V E + PV D+ + A+P + I Sbjct: 6 PIKIAVLPGDGIGIEVTEATLPVFEVLDVPVILNYGDIGWEFWKKEGAAIPSRTWQLIAS 65 Query: 384 NKVCLKGGLAT--------PVGGGVSSLN-------MQLRKELDLFASLVNCANVPGLPT 518 + L G + + + + N +QLR+ LDLFA++ C ++ Sbjct: 66 SDTVLLGAITSKPQREAKQELSNALKKSNPYYVSPVIQLRQGLDLFANVRPCFSI---DD 122 Query: 519 RHKNVDIVVIRE 554 + K + +IRE Sbjct: 123 QSKPFNFCIIRE 134
>LEU3_METCA (Q606F4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 360 Score = 38.5 bits (88), Expect = 0.013 Identities = 36/133 (27%), Positives = 56/133 (42%), Gaps = 24/133 (18%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAM-----------HAPVYFETYDVHGDMPAVPPAVIES 374 + ++PGDGIGP + +V++ + HA + YD HG P +E Sbjct: 5 IAVLPGDGIGPEIVAEALKVLDCLRSDFGLAVETEHALIGGAAYDAHG--TPFPKETLEL 62 Query: 375 IRRNKVCLKGGLATPVGGGVS-SLN-----MQLRKELDLFASLVNCANVPGL-------P 515 R L G + P + SL + LR EL+LF++L P L P Sbjct: 63 CRAADSILLGAVGGPKWEPLDYSLRPERGLLGLRSELELFSNLRPAVLYPQLVSASTLKP 122 Query: 516 TRHKNVDIVVIRE 554 +DI+++RE Sbjct: 123 EVVAGLDIMIVRE 135
>LEU3_CHLTE (P59028) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 352 Score = 38.5 bits (88), Expect = 0.013 Identities = 31/103 (30%), Positives = 45/103 (43%), Gaps = 17/103 (16%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFE-----------TYDVHGDMPAVPPAVIES 374 + IPGDGIGP V V+ A+ FE +YDVHG M + +E+ Sbjct: 5 IVSIPGDGIGPEVVAGALDVLNAVAKKHGFEVSVEEHLFGGASYDVHGSM--LTDETLEA 62 Query: 375 IRRNKVCLKGGLA------TPVGGGVSSLNMQLRKELDLFASL 485 + L G + P + +++RKEL LFA+L Sbjct: 63 CKNCDAVLLGAVGGYKWENLPHDKKPEAALLKIRKELGLFANL 105
>TTUC_BACSU (P42958) Probable tartrate dehydrogenase/decarboxylase (EC| 1.1.1.93) (EC 4.1.1.73) (TDH) (D-malate dehydrogenase [decarboxylating]) (EC 1.1.1.83) Length = 354 Score = 38.1 bits (87), Expect = 0.017 Identities = 37/128 (28%), Positives = 60/128 (46%), Gaps = 19/128 (14%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEA---MHAPVYF---------ETYDVHGDMPAVPPAVIE 371 + IPGDG+G V A E+V+ +H + F + Y HG M +P I Sbjct: 8 IAAIPGDGVGKEVVAAAEKVLHTAAEVHGGLSFSFTAFPWSCDYYLEHGKM--MPEDGIH 65 Query: 372 SIRRNKVCLKGGLATP--VGGGVS--SLNMQLRKELDLFASLVNCANVPGL--PTRHKN- 530 ++ + + G + P V +S L +++R+EL+L ++ + G+ P H N Sbjct: 66 TLTQFEAVFLGAVGNPKLVPDHISLWGLLLKIRRELELSINMRPAKQMAGITSPLLHPND 125 Query: 531 VDIVVIRE 554 D VVIRE Sbjct: 126 FDFVVIRE 133
>LEU3_BIFLO (Q8G500) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 343 Score = 38.1 bits (87), Expect = 0.017 Identities = 37/124 (29%), Positives = 59/124 (47%), Gaps = 15/124 (12%) Frame = +3 Query: 228 VTLIPGDGIGPLVT----GAVEQVMEAMHAPVYFETYDVHG-----DMPAVPPAVIESIR 380 + +IPGDGIG VT A+E+ E + A +E +D+ D +P E I+ Sbjct: 7 IAVIPGDGIGKEVTPWAQKALEKAAEGV-ADFEYENFDLGAERYLRDGAILPEDEEERIK 65 Query: 381 RNKVCLKGGLATP-VGGGV--SSLNMQLRKELDLFASLVNCANVPGLPTRHKN---VDIV 542 N L G + P + G+ L ++LR +LD + +L G+ + N +D V Sbjct: 66 ANDAILLGAVGDPRIKAGILERGLLLKLRFDLDQYVNLRPSKLYKGVTSPLANPGDIDFV 125 Query: 543 VIRE 554 V+RE Sbjct: 126 VVRE 129
>LEU3_CEPAC (Q12545) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 380 Score = 37.7 bits (86), Expect = 0.022 Identities = 42/135 (31%), Positives = 64/135 (47%), Gaps = 22/135 (16%) Frame = +3 Query: 216 TPRPVTLIPGDGIGPLVTGAVEQVMEAM--HAP-VYFE-TYDVHG----DMPAVP--PAV 365 T + ++PGD IGP + +V+ + H P ++F T D+ G D VP +V Sbjct: 3 TTYKILVLPGDHIGPEIMAEAIKVLTTIETHRPNLHFNLTTDLVGGTSIDTHGVPITQSV 62 Query: 366 IESIRRNKVCLKGGLATPVGGGV----SSLNMQLRKELDLFASLVNCA-NVPGL----PT 518 +++ + + L G + P GV S +QLR+ LD FA+L C VP L P Sbjct: 63 LDAAKASDAVLFGSIGGPEWAGVHPTPESGLLQLRQHLDAFANLRPCEFLVPSLVGASPI 122 Query: 519 RH---KNVDIVVIRE 554 R K +V+RE Sbjct: 123 REHVVKGTRFIVVRE 137
>LEU3_SYNPX (Q7U840) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 357 Score = 37.7 bits (86), Expect = 0.022 Identities = 35/133 (26%), Positives = 58/133 (43%), Gaps = 24/133 (18%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFE-----------TYDVHGDMPAVPPAVIES 374 V L+PGDGIGP +T Q++EA+ FE D G+ +P + +++ Sbjct: 6 VVLLPGDGIGPEITAVARQLLEAVSQRHGFELCFDGQLIGGSAIDACGE--PLPASTLDA 63 Query: 375 IRRNKVCLKGGLATPVGGGV------SSLNMQLRKELDLFASLVNCANVPGL-------P 515 + L + +P + + + LR + LFA+L VP L P Sbjct: 64 CKAADAVLLAAIGSPRFDNLPRDKRPETGLLGLRSGMALFANLRPVKIVPALIGASSLRP 123 Query: 516 TRHKNVDIVVIRE 554 + VD++V+RE Sbjct: 124 EVIEGVDLMVVRE 136
>LEU3_BACSU (P05645) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 365 Score = 37.7 bits (86), Expect = 0.022 Identities = 38/133 (28%), Positives = 56/133 (42%), Gaps = 24/133 (18%) Frame = +3 Query: 228 VTLIPGDGIGPLV----TGAVEQVMEAMHAPVYFE-------TYDVHGDMPAVPPAVIES 374 + L+PGDGIGP V T ++ V E + FE D H + +P + + Sbjct: 5 IALLPGDGIGPEVLESATDVLKSVAERFNHEFEFEYGLIGGAAIDEHHN--PLPEETVAA 62 Query: 375 IRRNKVCLKGGLATPV-GGGVSSLN-----MQLRKELDLFASLVNCANVPGLPTRH---- 524 + L G + P +S L + +RK+LDLFA+L L R Sbjct: 63 CKNADAILLGAVGGPKWDQNLSELRPEKGLLSIRKQLDLFANLRPVKVFESLSDRSPLKK 122 Query: 525 ---KNVDIVVIRE 554 NVD V++RE Sbjct: 123 EYIDNVDFVIVRE 135
>LEU3_PICAN (P34733) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 362 Score = 37.7 bits (86), Expect = 0.022 Identities = 36/130 (27%), Positives = 59/130 (45%), Gaps = 21/130 (16%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHAPV----YFETYDVHG---DMPAVP--PAVIESIR 380 + L+PGD +GP V +V+EA+ + + F + + G D VP +E+ + Sbjct: 5 IVLLPGDHVGPEVVAEAVKVLEAVSSAIGVKFNFSKHLIGGASIDAYGVPLSDEALEAAK 64 Query: 381 RNKVCLKGGLATPVGGGVSSLN----MQLRKELDLFASLVNCANV--------PGLPTRH 524 + L G + P G S +++RKEL+L+A+L C+ P Sbjct: 65 KADAVLLGAVGGPKWGTGSVRPEQGLLKIRKELNLYANLRPCSFASDALLKLSPLKSEIV 124 Query: 525 KNVDIVVIRE 554 K D VV+RE Sbjct: 125 KGTDFVVVRE 134
>LEU3_BACCO (P12010) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 366 Score = 37.7 bits (86), Expect = 0.022 Identities = 40/132 (30%), Positives = 61/132 (46%), Gaps = 23/132 (17%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAM-----HAPVYFETYDVHGDM-----PAVPPAVIESI 377 + ++PGDGIGP V A +V++ + H V FE + G +P ++ Sbjct: 5 LAVLPGDGIGPEVMDAAIRVLKTVLDNDGHEAV-FENALIGGAAIDEAGTPLPEETLDIC 63 Query: 378 RRNKVCLKGGLATPV-GGGVSSLN-----MQLRKELDLFASL------VNCANVPGLP-T 518 RR+ L G + P +SL + LRKE+ LFA+L N L Sbjct: 64 RRSDAILLGAVGGPKWDHNPASLRPEKGLLGLRKEMGLFANLRPVKAYATLLNASPLKRE 123 Query: 519 RHKNVDIVVIRE 554 R +NVD+V++RE Sbjct: 124 RVENVDLVIVRE 135
>LEU3_RHILO (Q98E57) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 367 Score = 37.7 bits (86), Expect = 0.022 Identities = 36/131 (27%), Positives = 58/131 (44%), Gaps = 24/131 (18%) Frame = +3 Query: 234 LIPGDGIGPLVTGAVEQVMEAMHAPV--YFET---------YDVHGDMPAVPPAVIESIR 380 L+PGDGIGP V++++ AM+ + F T YD HG A+ A + Sbjct: 8 LLPGDGIGPEAMAEVKKLISAMNEKLGSGFATDEGLVGGCAYDAHG--AAISDADMAKAM 65 Query: 381 RNKVCLKGGLATPVGGGV------SSLNMQLRKELDLFASLVNCANVPGLPTRH------ 524 L G + P V + ++LRK+++LFA+L P L Sbjct: 66 AADAVLFGAVGGPKWDAVPYEVRPEAGLLRLRKDMELFANLRPAICYPALAASSSLKQEV 125 Query: 525 -KNVDIVVIRE 554 + +DI+++RE Sbjct: 126 VEGLDILIVRE 136
>LEU3_PROMM (Q7V842) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 357 Score = 37.4 bits (85), Expect = 0.029 Identities = 33/131 (25%), Positives = 59/131 (45%), Gaps = 22/131 (16%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAM---HA-PVYFETYDVHG-----DMPAVPPAVIESIR 380 + L+PGDGIGP +T + +++A+ H + FE + + G +P + +E+ + Sbjct: 6 IVLLPGDGIGPEITAVAKLLLDALGHQHGFKLNFEQHPIGGVAIDASGSPLPASTLEACQ 65 Query: 381 RNKVCLKGGLATPVGGGVSSLN------MQLRKELDLFASLVNCANVPGLPTRH------ 524 + L + +P + + LR L LFA+L +P L Sbjct: 66 ASDAVLLAAIGSPRFDALPREQRPETGLLSLRAGLKLFANLRPVTILPALIDASSLKANV 125 Query: 525 -KNVDIVVIRE 554 K VD++V+RE Sbjct: 126 IKGVDLMVVRE 136
>LEU3_DESVH (Q726X1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 357 Score = 37.0 bits (84), Expect = 0.038 Identities = 36/134 (26%), Positives = 56/134 (41%), Gaps = 25/134 (18%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAM-----------HAPVYFETYDVHGDMPAVPPAVIES 374 + L+PGDGIGP + +V++A+ A + D G +P A +E+ Sbjct: 5 ICLLPGDGIGPEIVAQGTKVLDAVARRFGHTVSTSSALIGGAAIDATGS--PLPDATVEA 62 Query: 375 IRRNKVCLKGGLATPVGGGVSSLN------MQLRKELDLFASLVNCANVPGL-------- 512 R + L G + P + S + +RK L LFA+L A P L Sbjct: 63 CRTSDAVLLGAVGGPKWDDLPSEKRPEKGLLGIRKALGLFANLRPAALFPELAGACLLRA 122 Query: 513 PTRHKNVDIVVIRE 554 +D+VV+RE Sbjct: 123 DIAAAGLDLVVVRE 136
>LEU3_AZOSE (Q5P1J6) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 350 Score = 37.0 bits (84), Expect = 0.038 Identities = 35/129 (27%), Positives = 53/129 (41%), Gaps = 20/129 (15%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFE-------TYDVHGDMPAVPPAVIESIRRN 386 + ++PGDGIGP +T +V+EA+ E D GD P A + R Sbjct: 3 ICILPGDGIGPEITAEAVRVIEALDLKFEMEEALLGGAAVDATGD--PYPEATRKLAREA 60 Query: 387 KVCLKGGLATPVGGGVSSLN------MQLRKELDLFASLVNCANVPGL-------PTRHK 527 L G + P + + +RK+L LFA+L P L P Sbjct: 61 DAVLLGAVGGPKWDTLPREQRPERGLLGIRKDLGLFANLRPAILYPELANASSLKPEVVA 120 Query: 528 NVDIVVIRE 554 +DI+++RE Sbjct: 121 GLDILIVRE 129
>LEU3_THIFE (Q56268) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 358 Score = 36.6 bits (83), Expect = 0.049 Identities = 34/134 (25%), Positives = 55/134 (41%), Gaps = 23/134 (17%) Frame = +3 Query: 222 RPVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHG----------DMPAVPPAVIE 371 + + + GDGIGP + A QV++A+ + G D P +P A ++ Sbjct: 2 KKIAIFAGDGIGPEIVAAARQVLDAVDQAAHLGLRCTEGLVGGAALDASDDP-LPAASLQ 60 Query: 372 SIRRNKVCLKGGLATPVGGGVSSLN------MQLRKELDLFASLVNCANVPGL------- 512 + G + P ++LRK LDL+A+L P L Sbjct: 61 LAMAADAVILGAVGGPRWDAYPPAKRPEQGLLRLRKGLDLYANLRPAQIFPQLLDASPLR 120 Query: 513 PTRHKNVDIVVIRE 554 P ++VDI+V+RE Sbjct: 121 PELVRDVDILVVRE 134
>LEU3_BRAJA (Q89X19) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 370 Score = 36.6 bits (83), Expect = 0.049 Identities = 39/131 (29%), Positives = 60/131 (45%), Gaps = 24/131 (18%) Frame = +3 Query: 234 LIPGDGIGPLVTGAVEQVMEAMHAP--VYFET---------YDVH------GDMPAVPPA 362 L+PGDGIGP V G V+++++ +++ FET YD H GDM A Sbjct: 8 LLPGDGIGPEVMGEVKRLIDWLNSAGIAKFETDTGLVGGSAYDAHKVSISEGDMAKALAA 67 Query: 363 VIESIRRNKVCLKGGLATPVGGGVSSLNMQLRKELDLFASLVNCANVPGLPTRH------ 524 ++I V A P + ++LRK+L LFA+L P L Sbjct: 68 --DAIIFGAVGGPKWDAVPYEVRPEAGLLRLRKDLGLFANLRPAVCYPALADASSLKREA 125 Query: 525 -KNVDIVVIRE 554 + +DI+++RE Sbjct: 126 VEGLDIMIVRE 136
>LEU3_BACLD (Q65GI9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 370 Score = 36.2 bits (82), Expect = 0.064 Identities = 39/131 (29%), Positives = 58/131 (44%), Gaps = 22/131 (16%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVME--AMHAPVYFE-TYDVHGDM------PAVPPAVIESIR 380 + L+PGDGIGP V A V++ A H FE Y + G +P + + + Sbjct: 5 IALLPGDGIGPEVLDAAVDVLKSVAEHYQHEFEFEYGLIGGAAIDEAGAPLPEETVAACK 64 Query: 381 RNKVCLKGGLATPV-GGGVSSLN-----MQLRKELDLFASL------VNCANVPGLPTRH 524 L G + P S L + +RK+LDLFA+L + A L T + Sbjct: 65 AADAILLGAVGGPKWDQNPSELRPEKGLLAIRKQLDLFANLRPVKVFESLAGASPLKTEY 124 Query: 525 -KNVDIVVIRE 554 + VD V++RE Sbjct: 125 IEGVDFVIVRE 135
>LEU3_PSEHT (Q3IJS3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 358 Score = 35.8 bits (81), Expect = 0.084 Identities = 36/136 (26%), Positives = 55/136 (40%), Gaps = 27/136 (19%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAM-----------HAPVYFETYDVHGDMPAVPPAVIES 374 V ++ GDGIGP + A EQV++A+ H + D HG A+P + + + Sbjct: 8 VAVLAGDGIGPEIMAAAEQVLDAVSNKFGFTLNREHHAIGGAAIDKHG--KALPQSTVTA 65 Query: 375 IRRNKVCLKGGLATPVGGGV--------SSLNMQLRKELDLFASLVNCANVPGLPT---- 518 L G + P + SL + LRK LF +L +P L T Sbjct: 66 CENADAILFGAVGGPKWEHLPPDEQPERGSL-LPLRKHFGLFCNLRPAQLLPALSTASPL 124 Query: 519 ----RHKNVDIVVIRE 554 + DI+ +RE Sbjct: 125 RADISEQGFDILCVRE 140
>LEU3_CORJK (Q4JUQ0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 338 Score = 35.8 bits (81), Expect = 0.084 Identities = 36/123 (29%), Positives = 57/123 (46%), Gaps = 14/123 (11%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDV-------HGDMPAVPPAVIESIRRN 386 + +I GDGIG VT +V+ A+ V YD+ +G++ + ++S+R + Sbjct: 3 LAVIAGDGIGTEVTAEALKVLHALRDDVETTDYDLGARRYLRNGEL--LTDEDLDSLREH 60 Query: 387 KVCLKGGLATP--VGGGV--SSLNMQLRKELDLFASLVNCANVPGLPTRHKN---VDIVV 545 L G + P V GV L + LR +LD +L PG + N +D VV Sbjct: 61 DAILLGAIGDPRTVPAGVLERGLLLPLRFKLDHAVNLRPSKLYPGSSSPLANPGDIDFVV 120 Query: 546 IRE 554 +RE Sbjct: 121 VRE 123
>LEU3_LISMF (Q71Y34) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 350 Score = 35.8 bits (81), Expect = 0.084 Identities = 35/131 (26%), Positives = 55/131 (41%), Gaps = 22/131 (16%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHGD----------MPAVPPAVIESI 377 +T + GDGIGP + + QV+EA+ A Y T+++ +P + +++ Sbjct: 5 ITSLAGDGIGPEIMTSGLQVLEAV-AKKYNHTFEIESHPFGGAGIDVAQDPIPSSTLKAC 63 Query: 378 RRNKVCLKGGLATPVGGGVSSLN----MQLRKELDLFASLVNCANVPGLPTR-------- 521 R L G + P + LRK L LFA+ + VP T Sbjct: 64 RDADAILLGAIGGPKWDNAPKRPEDGLLALRKALGLFAN-IRPIQVPSSITHLSPLKKEI 122 Query: 522 HKNVDIVVIRE 554 +N D VV+RE Sbjct: 123 VENTDFVVVRE 133
>LEU3_LISIN (Q92A27) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 350 Score = 35.8 bits (81), Expect = 0.084 Identities = 35/133 (26%), Positives = 57/133 (42%), Gaps = 24/133 (18%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVH------------GDMPAVPPAVIE 371 +T + GDGIGP + + +++EA+ A Y T+++ GD +PP ++ Sbjct: 5 ITSLAGDGIGPEIMASGIKILEAI-AAKYNHTFEIESHPFGGAGIDAAGD--PIPPETLK 61 Query: 372 SIRRNKVCLKGGLATPVGGGVSSLN----MQLRKELDLFASLVNCANVPGLPTR------ 521 + + L G + P + LRK L LFA+ + VP T Sbjct: 62 ACQNADAILLGAIGGPKWDNAPKRPEDGLLALRKALGLFAN-IRPIQVPSSITHLSPLKK 120 Query: 522 --HKNVDIVVIRE 554 +N D VV+RE Sbjct: 121 EIVENTDFVVVRE 133
>LEU3_CORDI (Q6NHM7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 339 Score = 35.4 bits (80), Expect = 0.11 Identities = 36/123 (29%), Positives = 57/123 (46%), Gaps = 14/123 (11%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDV-------HGDMPAVPPAVIESIRRN 386 + +I GDGIGP VT +V+ A+ + YD+ +G++ A A + S+R + Sbjct: 3 LAVIGGDGIGPEVTAEALKVLNAVRDDIEVTDYDLGARRYLRNGELLA--DADLVSLREH 60 Query: 387 KVCLKGGLATP--VGGGV--SSLNMQLRKELDLFASLVNCANVPGLPTRHKN---VDIVV 545 L G + P V GV L +++R LD +L P + N +D VV Sbjct: 61 DAILLGAIGAPGEVPPGVLERGLLLKMRFALDHHVNLRPSKLYPTATSPLANPGDIDFVV 120 Query: 546 IRE 554 +RE Sbjct: 121 VRE 123
>LEU3_STRT2 (Q5M405) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 345 Score = 35.4 bits (80), Expect = 0.11 Identities = 35/132 (26%), Positives = 58/132 (43%), Gaps = 21/132 (15%) Frame = +3 Query: 222 RPVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDV----------HGDMPAVPPAVIE 371 + + + GDGIGP + A V++ + + + F+ YDV + +P A +E Sbjct: 3 KKIVTLSGDGIGPEIMAAGLGVLDKVASKIEFD-YDVDAKPFGGAGIDAEGHPLPKATLE 61 Query: 372 SIRRNKVCLKGGLATPVGGGVSSLNMQ----LRKELDLFASL--VNCANV-----PGLPT 518 + + L + P Q +RKEL+LFA++ V + P P Sbjct: 62 AAKSADAILLAAIGGPKYDNAPVRPEQGLLAIRKELNLFANIRPVRIFDALKHLSPLKPE 121 Query: 519 RHKNVDIVVIRE 554 R + VD VV+RE Sbjct: 122 RIEGVDFVVVRE 133
>LEU3_STRT1 (Q5LZF3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 345 Score = 35.4 bits (80), Expect = 0.11 Identities = 35/132 (26%), Positives = 58/132 (43%), Gaps = 21/132 (15%) Frame = +3 Query: 222 RPVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDV----------HGDMPAVPPAVIE 371 + + + GDGIGP + A V++ + + + F+ YDV + +P A +E Sbjct: 3 KKIVTLSGDGIGPEIMAAGLGVLDKVASKIEFD-YDVDAKPFGGAGIDAEGHPLPKATLE 61 Query: 372 SIRRNKVCLKGGLATPVGGGVSSLNMQ----LRKELDLFASL--VNCANV-----PGLPT 518 + + L + P Q +RKEL+LFA++ V + P P Sbjct: 62 AAKSADAILLAAIGGPKYDNAPVRPEQGLLAIRKELNLFANIRPVRIFDALKHLSPLKPE 121 Query: 519 RHKNVDIVVIRE 554 R + VD VV+RE Sbjct: 122 RIEGVDFVVVRE 133
>LEU3_RHOPA (Q6ND82) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 370 Score = 35.4 bits (80), Expect = 0.11 Identities = 35/131 (26%), Positives = 55/131 (41%), Gaps = 24/131 (18%) Frame = +3 Query: 234 LIPGDGIGPLVTGAVEQVM-----------EAMHAPVYFETYDVHGDMPAVPPAVIESIR 380 L+PGDGIG V V +++ E H V YD D A+ A + + Sbjct: 8 LLPGDGIGTEVMAEVSRLIDWLNKAGIASFETEHGLVGGAAYD--ADKVAITDATMALAQ 65 Query: 381 RNKVCLKGGLATPVGGGV------SSLNMQLRKELDLFASLVNCANVPGLPTRH------ 524 + + G + P GV + ++LRK+L LFA+L P L Sbjct: 66 ASDAVIFGAVGGPKWDGVPYDARPEAGLLRLRKDLGLFANLRPAVCYPALADSSSLKRDV 125 Query: 525 -KNVDIVVIRE 554 + +DI+++RE Sbjct: 126 VEGLDIMIVRE 136
>LEU3_BACSK (Q5WEN4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 364 Score = 35.4 bits (80), Expect = 0.11 Identities = 27/104 (25%), Positives = 49/104 (47%), Gaps = 16/104 (15%) Frame = +3 Query: 222 RPVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYD-----VHGDM-----PAVPPAVIE 371 + + L+PGDGIGP + ++V+E + A +Y T+ + GD +P ++ Sbjct: 3 KQILLLPGDGIGPEIIAETKRVLEEI-ARLYHHTFQFVEGRIGGDAIDATGSPLPEETLD 61 Query: 372 SIRRNKVCLKGGLATPVGGGVSSLN------MQLRKELDLFASL 485 + + L G + P G + +Q+RK L L+A+L Sbjct: 62 LAKGSDAILLGAVGGPKWDGNAPEKRPEKGLLQIRKALGLYANL 105
>LEU3_NEIMB (Q9JZI9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 356 Score = 35.0 bits (79), Expect = 0.14 Identities = 32/132 (24%), Positives = 56/132 (42%), Gaps = 23/132 (17%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAM----------HAPVYFETYDVHGDMPAVPPAVIESI 377 + ++ GDGIGP + +V++ + +AP+ E YD +G P Sbjct: 5 IAILRGDGIGPEIVAETVRVLDKLIAQGLDAGYEYAPLGGEAYDEYGH--PYPEFTQNLC 62 Query: 378 RRNKVCLKGGLATPVGGGVSSL------NMQLRKELDLFASLVNCANVPGL-------PT 518 R+ L G + +P + + +RK+L+LFA+L P L P Sbjct: 63 RKADAVLLGAVGSPQYDNLDRPLRPERGLLAIRKDLNLFANLRPAVLYPELANASTLKPE 122 Query: 519 RHKNVDIVVIRE 554 +DI+++RE Sbjct: 123 IVAGLDILIVRE 134
>LEU3_NEILA (P50180) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) (Fragment) Length = 313 Score = 35.0 bits (79), Expect = 0.14 Identities = 32/132 (24%), Positives = 56/132 (42%), Gaps = 23/132 (17%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAM----------HAPVYFETYDVHGDMPAVPPAVIESI 377 + ++ GDGIGP + +V++ + +AP+ E YD +G P Sbjct: 5 IAILRGDGIGPEIVAETVRVLDKLIEQGLDAGYEYAPLGGEAYDEYGH--PYPEFTQNLC 62 Query: 378 RRNKVCLKGGLATPVGGGVSSL------NMQLRKELDLFASLVNCANVPGL-------PT 518 R+ L G + +P + + +RK+L+LFA+L P L P Sbjct: 63 RKADAVLLGAVGSPQYDNLDRPLRPERGLLAIRKDLNLFANLRPAVLYPELANASTLKPE 122 Query: 519 RHKNVDIVVIRE 554 +DI+++RE Sbjct: 123 IVAGLDILIVRE 134
>LEU3B_ASPNG (P87257) 3-isopropylmalate dehydrogenase B (EC 1.1.1.85) (Beta-IPM| dehydrogenase B) (IMDH B) (3-IPM-DH B) Length = 371 Score = 34.7 bits (78), Expect = 0.19 Identities = 38/140 (27%), Positives = 63/140 (45%), Gaps = 31/140 (22%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMH-APVYFE---------TYDVHGDMPAVP------- 356 + ++PGDGIGP V +V+ + + + F + D HG P Sbjct: 9 ILVLPGDGIGPEVMAEAIKVLRTFNSSSMQFHLQEELIGGISIDTHGHSVTQPVKDAAVA 68 Query: 357 --PAVIESIRRNKV-CLKGGLATPVGGGVSSLNMQLRKELDLFASLVNCA-NVPG----- 509 + ++ +KV ++ GL P GG +Q+RK +D++A+L C+ +VP Sbjct: 69 ADAVLFAAVGGSKVDHIRRGLDGPEGG-----LLQVRKAMDIYANLRPCSVDVPSREIAR 123 Query: 510 --LPTRH---KNVDIVVIRE 554 P R + VD VV+RE Sbjct: 124 DFSPFRQEVIEGVDFVVVRE 143
>LEU3_CORGL (P94631) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 340 Score = 34.7 bits (78), Expect = 0.19 Identities = 33/123 (26%), Positives = 58/123 (47%), Gaps = 14/123 (11%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDV-------HGDMPAVPPAVIESIRRN 386 + +I GDGIGP VT +V+ A+ + YD+ +G++ + + S+R + Sbjct: 3 LAVIGGDGIGPEVTAEALKVLNAVRDDIETTDYDLGARRYLKNGEL--LTDEDLASLREH 60 Query: 387 KVCLKGGLATP--VGGGV--SSLNMQLRKELDLFASLVNCANVPGLPTRHKN---VDIVV 545 L G + P V G+ L +++R LD +L G+ + +N +D VV Sbjct: 61 DAILLGAIGAPGSVPPGILERGLLLKMRFALDHHVNLRPSKLYDGVESPLRNPGKIDFVV 120 Query: 546 IRE 554 +RE Sbjct: 121 VRE 123
>TTUC4_AGRVI (P70792) Probable tartrate dehydrogenase/decarboxylase ttuC' (EC| 1.1.1.93) (EC 4.1.1.73) (TDH) (D-malate dehydrogenase [decarboxylating]) (EC 1.1.1.83) Length = 358 Score = 34.3 bits (77), Expect = 0.24 Identities = 32/127 (25%), Positives = 58/127 (45%), Gaps = 18/127 (14%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHA-----PVYFETYDVHGDM-----PAVPPAVIESI 377 + IP DGIGP V A QV+EA+ ++ ET+D D +P +E + Sbjct: 6 IAAIPADGIGPEVIAAGLQVLEALEKRSGDFSIHTETFDWGSDYYKKNGVMMPADGLEQL 65 Query: 378 RRNKVCLKGGLATP-VGGGVS--SLNMQLRKELDLFASLVNCANVPGLPTRHKN-----V 533 ++ G + P V ++ L + + + D +A++ +PG+ +N + Sbjct: 66 KKFDAIFFGAVGAPDVPDHITLWGLRLPICQGFDQYANVRPTKVLPGITPPLRNCGPGDL 125 Query: 534 DIVVIRE 554 D V++RE Sbjct: 126 DWVIVRE 132
>AKSF_METJA (Q58991) Threo-isocitrate dehydrogenase [NAD] (EC 1.1.1.-)| Length = 347 Score = 34.3 bits (77), Expect = 0.24 Identities = 35/128 (27%), Positives = 57/128 (44%), Gaps = 19/128 (14%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVM------EAMHAPVYFETYDVHGDMPAVPPAVIESIRRNK 389 V +I GDGIG V +++ E + E +G+ A+P IE + Sbjct: 4 VCVIEGDGIGKEVIPEAIKILNELGEFEIIKGEAGLECLKKYGN--ALPEDTIEKAKEAD 61 Query: 390 VCLKGGLATPVGGGVSSLN---MQLRKELDLFASL--VNCANVPGLPTR--------HKN 530 + L G + +P G V + + LRK L+A++ +N + L + KN Sbjct: 62 IILFGAITSPKPGEVQNYKSPIITLRKMFHLYANVRPINNFGIGQLIGKIADYEFLNAKN 121 Query: 531 VDIVVIRE 554 +DIV+IRE Sbjct: 122 IDIVIIRE 129
>LEU3_PELUB (Q4FP17) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 368 Score = 34.3 bits (77), Expect = 0.24 Identities = 36/137 (26%), Positives = 62/137 (45%), Gaps = 26/137 (18%) Frame = +3 Query: 222 RPVTLIPGDGIGPLVTGAVEQVMEAMHA--PVYFE---------TYDVHGDMPAVPPAVI 368 R + L+PGDGIGP V V++V+ +++ + FE +YD HG + V Sbjct: 7 RKILLLPGDGIGPEVIQEVKKVILWLNSNKSLDFEIDEDLAGGCSYDKHG--TPITDEVF 64 Query: 369 ESIRRNKVCLKGGLATPVGGGVSSLN------MQLRKELDLFAS---------LVNCANV 503 ++ + G + P + ++LRKEL LFA+ LV+ + + Sbjct: 65 YKALESEFVMLGAVGGPKWDNLEFSKKPERALLKLRKELKLFANLRPAICFEQLVDASTL 124 Query: 504 PGLPTRHKNVDIVVIRE 554 P +DI+++RE Sbjct: 125 K--PEIVSGLDIMIVRE 139
>LEU3_NEIG1 (Q5F8T6) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 356 Score = 34.3 bits (77), Expect = 0.24 Identities = 32/132 (24%), Positives = 55/132 (41%), Gaps = 23/132 (17%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAM----------HAPVYFETYDVHGDMPAVPPAVIESI 377 + ++ GDGIGP + +V++ +AP+ E YD +G P Sbjct: 5 IAILRGDGIGPEIVAETVRVLDKFIAQGLDADYEYAPLGGEAYDEYGH--PYPEFTQNLC 62 Query: 378 RRNKVCLKGGLATPVGGGVSSL------NMQLRKELDLFASLVNCANVPGL-------PT 518 R+ L G + +P + + +RK+L+LFA+L P L P Sbjct: 63 RKADAVLLGAVGSPQYDNLDRPLRPERGLLAIRKDLNLFANLRPAVLYPELANASTLKPE 122 Query: 519 RHKNVDIVVIRE 554 +DI+++RE Sbjct: 123 IVAGLDILIVRE 134
>LEU3_LISMO (Q8Y5R8) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 350 Score = 34.3 bits (77), Expect = 0.24 Identities = 34/131 (25%), Positives = 55/131 (41%), Gaps = 22/131 (16%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHGD----------MPAVPPAVIESI 377 +T + GDGIGP + + QV+EA+ A Y T+++ +P + +++ Sbjct: 5 ITSLAGDGIGPEIMTSGLQVLEAV-AKKYNHTFEIESHPFGGAGIDVAQDPIPSSTLKAC 63 Query: 378 RRNKVCLKGGLATPVGGGVSSLN----MQLRKELDLFASLVNCANVPGLPTR-------- 521 + L G + P + LRK L LFA+ + VP T Sbjct: 64 QDADAILLGAIGGPKWDNAPKRPEDGLLALRKALGLFAN-IRPIQVPSSITHLSPLKKEI 122 Query: 522 HKNVDIVVIRE 554 +N D VV+RE Sbjct: 123 VENTDFVVVRE 133
>TTUC2_AGRVI (P70787) Probable tartrate dehydrogenase/decarboxylase ttuC (EC| 1.1.1.93) (EC 4.1.1.73) (TDH) (D-malate dehydrogenase [decarboxylating]) (EC 1.1.1.83) Length = 364 Score = 34.3 bits (77), Expect = 0.24 Identities = 32/127 (25%), Positives = 58/127 (45%), Gaps = 18/127 (14%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHA-----PVYFETYDVHGDM-----PAVPPAVIESI 377 + IP DGIGP V A QV+EA+ ++ ET+D D +P +E + Sbjct: 6 IAAIPADGIGPEVIAAGLQVLEALEKRSGDFSIHTETFDWGSDYYKKNGVMMPADGLEQL 65 Query: 378 RRNKVCLKGGLATP-VGGGVS--SLNMQLRKELDLFASLVNCANVPGLPTRHKN-----V 533 ++ G + P V ++ L + + + D +A++ +PG+ +N + Sbjct: 66 KKFDAIFFGAVGAPDVPDHITLWGLRLPICQGFDQYANVRPTKVLPGITPPLRNCGPGDL 125 Query: 534 DIVVIRE 554 D V++RE Sbjct: 126 DWVIVRE 132
>TTUC5_AGRVI (O34295) Probable tartrate dehydrogenase/decarboxylase ttuC' (EC| 1.1.1.93) (EC 4.1.1.73) (TDH) (D-malate dehydrogenase [decarboxylating]) (EC 1.1.1.83) Length = 358 Score = 33.9 bits (76), Expect = 0.32 Identities = 33/129 (25%), Positives = 60/129 (46%), Gaps = 20/129 (15%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHA-----PVYFETYD-------VHGDMPAVPPAVIE 371 + IP DGIGP V A QV+EA+ ++ ET+D HG M +P ++ Sbjct: 6 IAAIPADGIGPEVIAAGLQVLEALEQRSGDFKIHTETFDWGSDYYKKHGVM--MPADGLD 63 Query: 372 SIRRNKVCLKGGLATP-VGGGVS--SLNMQLRKELDLFASLVNCANVPGLPTRHKN---- 530 +++ G + P V ++ L + + + D +A++ +PG+ +N Sbjct: 64 KLKKFDAIFFGAVGAPDVPDHITLWGLRLPICQGFDQYANVRPTKILPGITPPLRNCGPG 123 Query: 531 -VDIVVIRE 554 +D V++RE Sbjct: 124 DLDWVIVRE 132
>TTUC3_AGRVI (O34296) Probable tartrate dehydrogenase/decarboxylase ttuC' (EC| 1.1.1.93) (EC 4.1.1.73) (TDH) (D-malate dehydrogenase [decarboxylating]) (EC 1.1.1.83) Length = 358 Score = 33.9 bits (76), Expect = 0.32 Identities = 33/129 (25%), Positives = 60/129 (46%), Gaps = 20/129 (15%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHA-----PVYFETYD-------VHGDMPAVPPAVIE 371 + IP DGIGP V A QV+EA+ ++ ET+D HG M +P ++ Sbjct: 6 IAAIPADGIGPEVIAAGLQVLEALEQRSGDFKIHTETFDWGSDYYKKHGVM--MPADGLD 63 Query: 372 SIRRNKVCLKGGLATP-VGGGVS--SLNMQLRKELDLFASLVNCANVPGLPTRHKN---- 530 +++ G + P V ++ L + + + D +A++ +PG+ +N Sbjct: 64 KLKKFDAIFFGAVGAPDVPDHITLWGLRLPICQGFDQYANVRPTKILPGITPPLRNCGPG 123 Query: 531 -VDIVVIRE 554 +D V++RE Sbjct: 124 DLDWVIVRE 132
>LEU3_CAUCR (Q9ABN3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 350 Score = 33.9 bits (76), Expect = 0.32 Identities = 28/97 (28%), Positives = 42/97 (43%), Gaps = 13/97 (13%) Frame = +3 Query: 234 LIPGDGIGPLVTGAVEQVMEAMHAPVYFE-------TYDVHGDMPAVPPAVIESIRRNKV 392 L+PGDGIGP V V +V A+ + + +YD HG + V E + Sbjct: 6 LLPGDGIGPEVCAQVRRVAAALTPDLKVDEALYGGASYDTHG--TPLTDEVREQALASDA 63 Query: 393 CLKGGLATPVGGGV------SSLNMQLRKELDLFASL 485 L G + P + + LRK +D+FA+L Sbjct: 64 VLMGAVGGPKWADAPRHLRPEAGLLNLRKAMDVFANL 100
>TTUC1_AGRVI (Q44471) Probable tartrate dehydrogenase/decarboxylase ttuC (EC| 1.1.1.93) (EC 4.1.1.73) (TDH) (D-malate dehydrogenase [decarboxylating]) (EC 1.1.1.83) Length = 364 Score = 33.9 bits (76), Expect = 0.32 Identities = 33/129 (25%), Positives = 60/129 (46%), Gaps = 20/129 (15%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHA-----PVYFETYD-------VHGDMPAVPPAVIE 371 + IP DGIGP V A QV+EA+ ++ ET+D HG M +P ++ Sbjct: 6 IAAIPADGIGPEVIAAGLQVLEALEQRSGDFKIHTETFDWGSDYYKKHGVM--MPADGLD 63 Query: 372 SIRRNKVCLKGGLATP-VGGGVS--SLNMQLRKELDLFASLVNCANVPGLPTRHKN---- 530 +++ G + P V ++ L + + + D +A++ +PG+ +N Sbjct: 64 KLKKFDAIFFGAVGAPDVPDHITLWGLRLPICQGFDQYANVRPTKILPGITPPLRNCGPG 123 Query: 531 -VDIVVIRE 554 +D V++RE Sbjct: 124 DLDWVIVRE 132
>LEU3_BURCE (Q845W3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 355 Score = 33.9 bits (76), Expect = 0.32 Identities = 33/129 (25%), Positives = 53/129 (41%), Gaps = 20/129 (15%) Frame = +3 Query: 228 VTLIPGDGIGP-------LVTGAVEQVMEAMHAPVYFETYDVHGDMPAVPPAVIESIRRN 386 + ++PGDGIGP V A+++ E APV Y+ G +P A ++ + Sbjct: 3 IAVLPGDGIGPEIVTEAVKVLNALDEKFELEQAPVGGAGYEARGH--PLPDATLKLAKEA 60 Query: 387 KVCLKGGLATPVGGGV------SSLNMQLRKELDLFASLVNCANVPGL-------PTRHK 527 L G + + + LRK L+LFA+ P L P Sbjct: 61 DAILFGAVGDWKYDSLERALRPEQAILGLRKHLELFANFRPAICYPQLVDASPLKPELVA 120 Query: 528 NVDIVVIRE 554 +DI+++RE Sbjct: 121 GLDILIVRE 129
>LEU3_COREF (Q8FPV5) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 340 Score = 33.9 bits (76), Expect = 0.32 Identities = 37/125 (29%), Positives = 59/125 (47%), Gaps = 16/125 (12%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDV---------HGDMPAVPPAVIESIR 380 + +I GDGIGP VT +V+ A+ A + ET D+ +G++ + + +R Sbjct: 3 LAVIGGDGIGPEVTDEALKVLRALRADI--ETTDLDLGARRYLRNGEL--LTDEDLALLR 58 Query: 381 RNKVCLKGGLATP--VGGGV--SSLNMQLRKELDLFASLVNCANVPGLPTRHKN---VDI 539 + L G + P V GV L ++LR LD +L G+ + KN +D Sbjct: 59 EHDAILLGAIGAPGSVPPGVLERGLLLKLRFALDHHVNLRPSKLYEGVESPLKNPGEIDF 118 Query: 540 VVIRE 554 VV+RE Sbjct: 119 VVVRE 123
>LEU3_GLUOX (Q5FUG5) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 369 Score = 33.9 bits (76), Expect = 0.32 Identities = 36/131 (27%), Positives = 56/131 (42%), Gaps = 24/131 (18%) Frame = +3 Query: 234 LIPGDGIGPLVTGAVEQVMEAMHAP-----------VYFETYDVHGDMPAVPPAVIESIR 380 ++ GDGIGP V V +++ M A V + VHG + VIE R Sbjct: 9 VLAGDGIGPEVMREVARIVHWMSAHRGLKLEITEELVGAASLAVHG--VPIRDEVIELAR 66 Query: 381 RNKVCLKGGLATPVGGGVSSLN------MQLRKELDLFASLVNCANVPGL-------PTR 521 ++ L G + P V ++LRKEL+LFA+L L P Sbjct: 67 QSDAVLFGSVGDPAWSHVGFDKRPEVAILKLRKELELFANLRPAKLFDALIDASALKPEV 126 Query: 522 HKNVDIVVIRE 554 + +D++++RE Sbjct: 127 VRGLDLMIVRE 137
>LEU3_STRAW (Q82JN6) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 347 Score = 33.5 bits (75), Expect = 0.42 Identities = 32/123 (26%), Positives = 57/123 (46%), Gaps = 14/123 (11%) Frame = +3 Query: 228 VTLIPGDGIG-PLVTGAVEQVMEAMHAPVYFETYD-------VHGDMPAVPPAVIESIRR 383 + +IPGDGIG +V ++ + A+ + V ET + H + A ++++++ Sbjct: 7 LAVIPGDGIGQEVVAQGLKVLSAALPSDVKLETKEFDFGARRYHATGETLTDADLDALKQ 66 Query: 384 NKVCLKGGLATP-VGGGV--SSLNMQLRKELDLFASLVNCANVPGLPT---RHKNVDIVV 545 + L G + P V GV ++LR D +L +PG+ T +D VV Sbjct: 67 HDAILLGAIGDPSVPSGVLERGFLLKLRFAFDHHVNLRPSKLLPGVETPLAGQPEIDFVV 126 Query: 546 IRE 554 +RE Sbjct: 127 VRE 129
>LEU3_ZYMMO (Q5NPQ9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 349 Score = 33.5 bits (75), Expect = 0.42 Identities = 33/130 (25%), Positives = 57/130 (43%), Gaps = 21/130 (16%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAM--------HAPVYFETYDVHGDMPAVPPAVIESIRR 383 + L+ GDGIGP +T ++++A+ A + + V G +P ++ + Sbjct: 3 IALLAGDGIGPEITAEAVKILKAVVGQEIEFDEALIGGAAWKVTGS--PLPEETLKLCKN 60 Query: 384 NKVCLKGGLATPVGGGV------SSLNMQLRKELDLFASLVNCANVPGL----PTRHKNV 533 + L G + P + + LRKELDLFA+L P L P + V Sbjct: 61 SDAILFGSVGDPECDHLERALRPEQAILGLRKELDLFANLRPARLFPELQAESPLKENIV 120 Query: 534 ---DIVVIRE 554 D++++RE Sbjct: 121 TGTDLMIVRE 130
>LEU31_DECAR (Q47HR1) 3-isopropylmalate dehydrogenase 1 (EC 1.1.1.85) (Beta-IPM| dehydrogenase 1) (IMDH 1) (3-IPM-DH 1) Length = 350 Score = 33.5 bits (75), Expect = 0.42 Identities = 33/129 (25%), Positives = 53/129 (41%), Gaps = 20/129 (15%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFE-------TYDVHGDMPAVPPAVIESIRRN 386 + ++PGDGIGP +T +V+ ++ E D G+ P A + R Sbjct: 3 ICVLPGDGIGPEITAQAVRVLNSLDLKFEMEEALLGGGAVDATGN--PYPEATQKLARAA 60 Query: 387 KVCLKGGLATPVGGGVSSLN------MQLRKELDLFASLVNCANVPGL-------PTRHK 527 L G + P + + +RK+L+LFA+L P L P Sbjct: 61 DAVLLGAVGGPKWDSLPREQRPERGLLGIRKDLNLFANLRPAILYPELANASTLKPEVVA 120 Query: 528 NVDIVVIRE 554 +DI++IRE Sbjct: 121 GLDILIIRE 129
>LEU3_NEIMA (Q9JU79) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 356 Score = 33.5 bits (75), Expect = 0.42 Identities = 31/132 (23%), Positives = 55/132 (41%), Gaps = 23/132 (17%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAM----------HAPVYFETYDVHGDMPAVPPAVIESI 377 + ++ GDGIGP + +V++ + +AP+ E YD +G P Sbjct: 5 IAILRGDGIGPEIVAETVRVLDKLIAQGLDVGYEYAPLGGEAYDEYGH--PYPEFTQNLC 62 Query: 378 RRNKVCLKGGLATPVGGGVSSL------NMQLRKELDLFASLVNCANVPGLPTRH----- 524 R+ L G + +P + + +RK+L+LFA+L P L Sbjct: 63 RKADAVLLGAVGSPQYDNLDRPLRPERGLLAIRKDLNLFANLRPAILYPELANASTLKSE 122 Query: 525 --KNVDIVVIRE 554 +DI+++RE Sbjct: 123 IVAGLDILIVRE 134
>LEU3_SHIBS (Q326G2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 33.1 bits (74), Expect = 0.54 Identities = 22/75 (29%), Positives = 33/75 (44%), Gaps = 11/75 (14%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAM-----------HAPVYFETYDVHGDMPAVPPAVIES 374 + ++PGDGIGP V +V++A+ H V D HG +PPA +E Sbjct: 7 IAVLPGDGIGPEVMTQALKVLDAVRNRFAMRITTSHYDVGGAAIDNHGQ--PLPPATVEG 64 Query: 375 IRRNKVCLKGGLATP 419 + L G + P Sbjct: 65 CEQADAVLFGSVGGP 79
>LEU3_ECOLI (P30125) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 362 Score = 33.1 bits (74), Expect = 0.54 Identities = 22/75 (29%), Positives = 33/75 (44%), Gaps = 11/75 (14%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAM-----------HAPVYFETYDVHGDMPAVPPAVIES 374 + ++PGDGIGP V +V++A+ H V D HG +PPA +E Sbjct: 6 IAVLPGDGIGPEVMTQALKVLDAVRNRFAMRITTSHYDVGGAAIDNHGQ--PLPPATVEG 63 Query: 375 IRRNKVCLKGGLATP 419 + L G + P Sbjct: 64 CEQADAVLFGSVGGP 78
>LEU3_ECOL6 (Q8FL76) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 362 Score = 33.1 bits (74), Expect = 0.54 Identities = 22/75 (29%), Positives = 33/75 (44%), Gaps = 11/75 (14%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAM-----------HAPVYFETYDVHGDMPAVPPAVIES 374 + ++PGDGIGP V +V++A+ H V D HG +PPA +E Sbjct: 6 IAVLPGDGIGPEVMTQALKVLDAVRNRFAMRITTSHYDVGGAAIDNHGQ--PLPPATVEG 63 Query: 375 IRRNKVCLKGGLATP 419 + L G + P Sbjct: 64 CEQADAVLFGSVGGP 78
>LEU3_ECO57 (Q8X9Z9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 362 Score = 33.1 bits (74), Expect = 0.54 Identities = 22/75 (29%), Positives = 33/75 (44%), Gaps = 11/75 (14%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAM-----------HAPVYFETYDVHGDMPAVPPAVIES 374 + ++PGDGIGP V +V++A+ H V D HG +PPA +E Sbjct: 6 IAVLPGDGIGPEVMTQALKVLDAVRNRFAMRITTSHYDVGGAAIDNHGQ--PLPPATVEG 63 Query: 375 IRRNKVCLKGGLATP 419 + L G + P Sbjct: 64 CEQADAVLFGSVGGP 78
>LEU3_BACCA (P05644) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 366 Score = 33.1 bits (74), Expect = 0.54 Identities = 36/135 (26%), Positives = 57/135 (42%), Gaps = 26/135 (19%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHGDM---------PAVPPAVIESIR 380 + ++PGDGIG VT +V++A+ E +G + +P + R Sbjct: 6 IAVLPGDGIGKEVTSGAVEVLKAVGIRFGHEFTFEYGLIGGAAIDEAGTPLPEETVRLCR 65 Query: 381 RNKVCLKGGLATPVGGGVSSLN----------MQLRKELDLFASL--VNC-----ANVPG 509 + L G VGG N + +RK+LDL+A+L V C + P Sbjct: 66 ESDAVLLGA----VGGPKWDDNPPHLRPEKGLLAIRKQLDLYANLRPVVCYDSLVSRSPL 121 Query: 510 LPTRHKNVDIVVIRE 554 P + VD V++RE Sbjct: 122 KPDLVQGVDFVIVRE 136
>LEU3_PSEPK (Q88LE5) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 360 Score = 33.1 bits (74), Expect = 0.54 Identities = 34/133 (25%), Positives = 57/133 (42%), Gaps = 22/133 (16%) Frame = +3 Query: 222 RPVTLIPGDGIGPLVTGAVEQVMEAMHAPV---YFETYDVHG----DMPAVPPA--VIES 374 + + ++PGDGIGP + +V+E + + +DV G D VP A +E Sbjct: 3 KQILILPGDGIGPEIMAEAVKVLELANDKFQLGFSLAHDVIGGAAIDKHGVPLADETLER 62 Query: 375 IRRNKVCLKGGLATPVGGGV------SSLNMQLRKELDLFASLVNCANVPGL-------P 515 R+ L G + P + +++R +L LFA+L P L P Sbjct: 63 ARKADAVLLGAVGGPKWDKIERDIRPERGLLKIRSQLGLFANLRPAILYPQLADASSLKP 122 Query: 516 TRHKNVDIVVIRE 554 +DI+++RE Sbjct: 123 EIVSGLDILIVRE 135
>LEU3_NITWN (Q3SNU3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 370 Score = 33.1 bits (74), Expect = 0.54 Identities = 34/129 (26%), Positives = 56/129 (43%), Gaps = 22/129 (17%) Frame = +3 Query: 234 LIPGDGIGPLVTGAVEQVMEAMHAP--VYFETYD-------VHGDMPAVPPAVIESIRRN 386 L+PGDGIGP V V++++ + A FET + D ++ A + Sbjct: 8 LLPGDGIGPEVMAEVKRLVGWLDAQGIAKFETEEGLVGGASYDADKVSITDATMAKALAA 67 Query: 387 KVCLKGGLATPVGGGV------SSLNMQLRKELDLFASLVNCANVPGL-------PTRHK 527 L G + P V + ++LRK+L L+A+L P L P + Sbjct: 68 DAVLFGAVGGPKWDSVPYEVRPEAGLLRLRKDLALYANLRPAICYPALAESSSLKPEVVE 127 Query: 528 NVDIVVIRE 554 +DI+++RE Sbjct: 128 GLDIMIVRE 136
>LEU3_RHOBA (Q7UIE1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 359 Score = 32.7 bits (73), Expect = 0.71 Identities = 27/101 (26%), Positives = 44/101 (43%), Gaps = 15/101 (14%) Frame = +3 Query: 228 VTLIPGDGIGPLVTG----AVEQVMEAMHAPVYFETYDVHG-----DMPAVPPAVIESIR 380 + L+PGDGIGP + + +V E F ++ + G +P I++ R Sbjct: 5 IVLLPGDGIGPEIVEQARLVLVKVAERFGHTFDFSSHQIGGIAIDETGDPLPQPTIDACR 64 Query: 381 RNKVCLKGGLATPVGGGVSSLN------MQLRKELDLFASL 485 L G + P S+ +++RKEL LFA+L Sbjct: 65 NAAAILLGAVGGPKWDDPSAKTRPEAGLLKIRKELGLFANL 105
>LEU3_VIBVY (Q7MP78) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 32.7 bits (73), Expect = 0.71 Identities = 37/136 (27%), Positives = 58/136 (42%), Gaps = 27/136 (19%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAM---HAPVYFE---------TYDVHGDMPAVPPAVIE 371 + ++PGDGIGP V +V++A+ HA ++FE D HG +P + + Sbjct: 8 IAVLPGDGIGPEVMAQAHKVLDAIEKKHA-IHFEREEHDVGGIAIDNHG--CPLPQSTVT 64 Query: 372 SIRRNKVCLKGGLATPVGGGVSSLN-------MQLRKELDLFASLVNCANVPGL----PT 518 + + L G + P + + + LRK LF +L GL P Sbjct: 65 ACEESDAVLFGSVGGPKWEHLPPNDQPERGALLPLRKHFQLFCNLRPAQIHSGLEAFSPL 124 Query: 519 R----HKNVDIVVIRE 554 R + DIVV+RE Sbjct: 125 RADISGRGFDIVVVRE 140
>LEU3_VIBVU (Q8DEE0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 32.7 bits (73), Expect = 0.71 Identities = 37/136 (27%), Positives = 58/136 (42%), Gaps = 27/136 (19%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAM---HAPVYFE---------TYDVHGDMPAVPPAVIE 371 + ++PGDGIGP V +V++A+ HA ++FE D HG +P + + Sbjct: 8 IAVLPGDGIGPEVMAQAHKVLDAIEKKHA-IHFEREEHDVGGIAIDNHG--CPLPQSTVT 64 Query: 372 SIRRNKVCLKGGLATPVGGGVSSLN-------MQLRKELDLFASLVNCANVPGL----PT 518 + + L G + P + + + LRK LF +L GL P Sbjct: 65 ACEESDAVLFGSVGGPKWEHLPPNDQPERGALLPLRKHFQLFCNLRPAQIHSGLEAFSPL 124 Query: 519 R----HKNVDIVVIRE 554 R + DIVV+RE Sbjct: 125 RADISGRGFDIVVVRE 140
>LEU3_SYNP6 (Q5MZ40) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 365 Score = 32.7 bits (73), Expect = 0.71 Identities = 33/133 (24%), Positives = 55/133 (41%), Gaps = 24/133 (18%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAM-----------HAPVYFETYDVHGDMPAVPPAVIES 374 +TL+PGDGIGP + ++ A+ A + D G+ +P A + + Sbjct: 7 ITLLPGDGIGPEIMAVTVDILRAIGRQFDLNFEFEEALIGGSAIDATGE--PLPEATLAT 64 Query: 375 IRRNKVCLKGGL------ATPVGGGVSSLNMQLRKELDLFASLVNCANVPGLPTRH---- 524 R + L + + P + + LR L LFA+L A +P L Sbjct: 65 CRNSDAVLLAAIGGYKWDSLPRSQRPETGLLGLRAGLGLFANLRPAAILPQLVDASSLKR 124 Query: 525 ---KNVDIVVIRE 554 + VD++V+RE Sbjct: 125 EVIEGVDLMVVRE 137
>LEU3_SALTY (P37412) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 32.7 bits (73), Expect = 0.71 Identities = 25/102 (24%), Positives = 42/102 (41%), Gaps = 16/102 (15%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHGDMPAV---------PPAVIESIR 380 + ++PGDGIGP V +VM+A+ + H D+ + P A +E Sbjct: 7 IAVLPGDGIGPEVMAQALKVMDAVRSRFDMRITTSHYDVGGIAIDNHGHPLPKATVEGCE 66 Query: 381 RNKVCLKGGLATPVGGGVSSLN-------MQLRKELDLFASL 485 + L G + P + + + LRK LF++L Sbjct: 67 QADAILFGSVGGPKWENLPPESQPERGALLPLRKHFKLFSNL 108
>LEU3_SALCH (Q57TE7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 32.7 bits (73), Expect = 0.71 Identities = 25/102 (24%), Positives = 42/102 (41%), Gaps = 16/102 (15%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHGDMPAV---------PPAVIESIR 380 + ++PGDGIGP V +VM+A+ + H D+ + P A +E Sbjct: 7 IAVLPGDGIGPEVMAQALKVMDAVRSRFDMRITTSHYDVGGIAIDNHGHPLPKATVEGCE 66 Query: 381 RNKVCLKGGLATPVGGGVSSLN-------MQLRKELDLFASL 485 + L G + P + + + LRK LF++L Sbjct: 67 QADAILFGSVGGPKWENLPPESQPERGALLPLRKHFKLFSNL 108
>Y1617_METMA (Q8PWH0) UPF0272 protein MM1617| Length = 396 Score = 32.7 bits (73), Expect = 0.71 Identities = 15/39 (38%), Positives = 21/39 (53%), Gaps = 5/39 (12%) Frame = +3 Query: 333 HGDMPAVPPAVIESIRRNKVCLKGG-----LATPVGGGV 434 HG +P PA +E +RR K+ +GG L TP G + Sbjct: 159 HGTLPVPAPATLEILRRGKLYFRGGNVNKELLTPTGAAI 197
>LEU3_STAHJ (Q4L7U1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 346 Score = 32.7 bits (73), Expect = 0.71 Identities = 32/129 (24%), Positives = 53/129 (41%), Gaps = 20/129 (15%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFE----TYDVHG---DMPAV--PPAVIESIR 380 + +PGDGIGP + +++E + F+ +YD G D V P + + + Sbjct: 5 IVALPGDGIGPEILSGTLELLELISKKYKFDYQLTSYDFGGAAIDSHGVPLPDDTLNACK 64 Query: 381 RNKVCLKGGLATPVGGGVSSLNMQ----LRKELDLFASLVNCANVPGL-------PTRHK 527 L G + P ++ Q LRK L LFA++ G +R K Sbjct: 65 NADAILLGAVGGPQWTDPNNRPEQGLLALRKSLGLFANIRPTKVTEGTSHFSPIKESRVK 124 Query: 528 NVDIVVIRE 554 D +++RE Sbjct: 125 GTDFIIVRE 133
>LEU3_BURPS (Q63JL2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 355 Score = 32.7 bits (73), Expect = 0.71 Identities = 33/129 (25%), Positives = 52/129 (40%), Gaps = 20/129 (15%) Frame = +3 Query: 228 VTLIPGDGIGP-------LVTGAVEQVMEAMHAPVYFETYDVHGDMPAVPPAVIESIRRN 386 + ++PGDGIGP V A+++ E APV Y+ G +P A + + Sbjct: 3 IAVLPGDGIGPEIVNEAVKVLNALDEKFELEQAPVGGAGYEASGH--PLPDATLALAKEA 60 Query: 387 KVCLKGGLATPVGGGV------SSLNMQLRKELDLFASLVNCANVPGL-------PTRHK 527 L G + + + LRK L+LFA+ P L P Sbjct: 61 DAILFGAVGDWKYDSLERALRPEQAILGLRKHLELFANFRPAICYPQLVDASPLKPELVA 120 Query: 528 NVDIVVIRE 554 +DI+++RE Sbjct: 121 GLDILIVRE 129
>LEU3_BURMA (Q62AI9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 355 Score = 32.7 bits (73), Expect = 0.71 Identities = 33/129 (25%), Positives = 52/129 (40%), Gaps = 20/129 (15%) Frame = +3 Query: 228 VTLIPGDGIGP-------LVTGAVEQVMEAMHAPVYFETYDVHGDMPAVPPAVIESIRRN 386 + ++PGDGIGP V A+++ E APV Y+ G +P A + + Sbjct: 3 IAVLPGDGIGPEIVNEAVKVLNALDEKFELEQAPVGGAGYEASGH--PLPDATLALAKEA 60 Query: 387 KVCLKGGLATPVGGGV------SSLNMQLRKELDLFASLVNCANVPGL-------PTRHK 527 L G + + + LRK L+LFA+ P L P Sbjct: 61 DAILFGAVGDWKYDSLERALRPEQAILGLRKHLELFANFRPAICYPQLVDASPLKPELVA 120 Query: 528 NVDIVVIRE 554 +DI+++RE Sbjct: 121 GLDILIVRE 129
>CSKI1_HUMAN (Q8WXD9) Caskin-1 (CASK-interacting protein 1)| Length = 1431 Score = 32.3 bits (72), Expect = 0.93 Identities = 34/133 (25%), Positives = 46/133 (34%), Gaps = 16/133 (12%) Frame = -1 Query: 508 PGTLAQLTREAKRSSSLRSCML-------REETPPPTGVARPPLRQTLLRRMDSMTAGGT 350 PGT + R + S++ + R+ PP T PP T R GG Sbjct: 735 PGTPPREARPGRHGHSIKRASVPPVPGKPRQVLPPGTSHFTPPQTPTKTRPGSPQALGGP 794 Query: 349 AGMSPWTSYVS------K*TGACMASMTCSTAPVTRG---PMPSPGMSVTGRGVPSPGRG 197 G +P T+ V T M+ + +P RG +P P G P P Sbjct: 795 HGPAPATAKVKPTPQLLPPTERPMSPRSLPQSPTHRGFAYVLPQPVEGEVGPAAPGP--- 851 Query: 196 M*VTVRRAPPPWP 158 APPP P Sbjct: 852 -------APPPVP 857
>LEU3_SYMTH (Q67JY2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 368 Score = 32.3 bits (72), Expect = 0.93 Identities = 35/134 (26%), Positives = 54/134 (40%), Gaps = 25/134 (18%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFE-----------TYDVHGDMPAVPPAVIES 374 + +PGDGIGP VT V++A A F YD G P ++ Sbjct: 8 IACLPGDGIGPEVTRGAVTVLQAAAAAYGFRLEFSEYLVGGAAYDAVG--TPFPDETRDA 65 Query: 375 IRRNKVCLKGGLATPVGGGV------SSLNMQLRKELDLFASLVNCANVPGL----PTRH 524 R L G + P G+ + + +RK DL+A+L P L P ++ Sbjct: 66 CDRADAILFGAVGGPRYEGLPWDLRPEAGLLAIRKRYDLYANLRPILLYPPLKDASPLKN 125 Query: 525 K----NVDIVVIRE 554 + VD +++RE Sbjct: 126 EIIGGGVDFIIVRE 139
>LEU3_SHISS (Q3Z5T7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 32.3 bits (72), Expect = 0.93 Identities = 22/75 (29%), Positives = 32/75 (42%), Gaps = 11/75 (14%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAM-----------HAPVYFETYDVHGDMPAVPPAVIES 374 + ++PGDGIGP V +V+ A+ H V D HG +PPA +E Sbjct: 7 IAVLPGDGIGPEVMTQALKVLNAVRNRFAMRITTSHYDVGGAAIDNHGQ--PLPPATVEG 64 Query: 375 IRRNKVCLKGGLATP 419 + L G + P Sbjct: 65 CEQADAVLFGSVGGP 79
>LEU3_SHIDS (Q32K21) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 32.3 bits (72), Expect = 0.93 Identities = 22/75 (29%), Positives = 32/75 (42%), Gaps = 11/75 (14%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAM-----------HAPVYFETYDVHGDMPAVPPAVIES 374 + +PGDGIGP V +V++A+ H V D HG +PPA +E Sbjct: 7 IAALPGDGIGPEVMTQALKVLDAVRNRFAMRITTSHYDVGGAAIDNHGQ--PLPPATVEG 64 Query: 375 IRRNKVCLKGGLATP 419 + L G + P Sbjct: 65 CEQADAVLFGSVGGP 79
>LEU3_SALTI (Q8Z9I1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 32.3 bits (72), Expect = 0.93 Identities = 27/102 (26%), Positives = 44/102 (43%), Gaps = 16/102 (15%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHA----PVYFETYDVHG-----DMPAVPPAVIESIR 380 + ++PGDGIGP V +VM+A+ + + YDV G +P A +E Sbjct: 7 IAVLPGDGIGPEVMAQALKVMDAVRSRFDMRITTSRYDVGGIAIDNHGHPLPKATVEGCE 66 Query: 381 RNKVCLKGGLATPVGGGVSSLN-------MQLRKELDLFASL 485 + L G + P + + + LRK LF++L Sbjct: 67 QADAILFGSVGGPKWENLPPESQPERGALLPLRKHFKLFSNL 108
>LEU3_SALPA (Q5PDG2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 32.3 bits (72), Expect = 0.93 Identities = 27/102 (26%), Positives = 44/102 (43%), Gaps = 16/102 (15%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHA----PVYFETYDVHG-----DMPAVPPAVIESIR 380 + ++PGDGIGP V +VM+A+ + + YDV G +P A +E Sbjct: 7 IAVLPGDGIGPEVMAQALKVMDAVRSRFDMRITTSRYDVGGIAIDNHGHPLPKATVEGCE 66 Query: 381 RNKVCLKGGLATPVGGGVSSLN-------MQLRKELDLFASL 485 + L G + P + + + LRK LF++L Sbjct: 67 QADAILFGSVGGPKWENLPPESQPERGALLPLRKHFKLFSNL 108
>LEU3_XANC5 (Q3BPJ8) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 357 Score = 32.3 bits (72), Expect = 0.93 Identities = 34/135 (25%), Positives = 58/135 (42%), Gaps = 24/135 (17%) Frame = +3 Query: 222 RPVTLIPGDGIGPLVTGAVEQVMEAMHAP-------VYFE----TYDVHGDMPAVPPAVI 368 + + ++PGDGIGP + +V++ + A VY E YD +G + + Sbjct: 3 KQILILPGDGIGPEIMAEAVKVLKRIDAQHGLGFELVYDELGGAAYDKYGS--PLADETL 60 Query: 369 ESIRRNKVCLKGGLATPVGGGVS-SLN-----MQLRKELDLFASLVNCANVPGL------ 512 E R L G + P + SL +++R +L LFA+L P L Sbjct: 61 ERARAADAVLLGAVGGPQWDTIDPSLRPERGLLKIRSQLGLFANLRPALLYPQLADASTL 120 Query: 513 -PTRHKNVDIVVIRE 554 P +D++++RE Sbjct: 121 KPEVVAGLDLLILRE 135
>Y429_METAC (Q8TTK2) UPF0272 protein MA0429| Length = 396 Score = 32.3 bits (72), Expect = 0.93 Identities = 15/41 (36%), Positives = 22/41 (53%), Gaps = 5/41 (12%) Frame = +3 Query: 333 HGDMPAVPPAVIESIRRNKVCLKGG-----LATPVGGGVSS 440 HG +P PA +E +R+ K+ +GG L TP G + S Sbjct: 159 HGTLPVPAPATLEILRKGKLYFRGGSVNKELLTPTGAAILS 199
>LEU3_SHIFL (Q83SP1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 362 Score = 32.3 bits (72), Expect = 0.93 Identities = 22/75 (29%), Positives = 32/75 (42%), Gaps = 11/75 (14%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAM-----------HAPVYFETYDVHGDMPAVPPAVIES 374 + ++PGDGIGP V +V+ A+ H V D HG +PPA +E Sbjct: 6 IAVLPGDGIGPEVMTQALKVLNAVRNRFAMRITTSHYDVGGAAIDNHGQ--PLPPATVEG 63 Query: 375 IRRNKVCLKGGLATP 419 + L G + P Sbjct: 64 CEQADAVLFGSVGGP 78
>LEU3_ANASP (Q8YXA2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 362 Score = 32.3 bits (72), Expect = 0.93 Identities = 35/141 (24%), Positives = 56/141 (39%), Gaps = 32/141 (22%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHGDM--------------PAVPPAV 365 +TL+PGDGIGP + V++ V + +D+ D +P A Sbjct: 7 ITLLPGDGIGPEIMAVAVDVLK-----VVGQQFDIQFDFQEALIGGAAIDATGEPLPSAT 61 Query: 366 IESIRRNKVCLKGGLA-----------TPVGGGVSSLNMQLRKELDLFASLVNCANVPGL 512 +++ R + L + P GG + LR L+LFA+L +P L Sbjct: 62 LDTCRHSDAVLLAAIGGYKWDSLPPHQRPEGG-----LLGLRAGLELFANLRPAQILPQL 116 Query: 513 PTRH-------KNVDIVVIRE 554 + VDI+V+RE Sbjct: 117 IDASTLKREVVEGVDIMVVRE 137
>LEU3_BUCTS (O31292) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 364 Score = 32.3 bits (72), Expect = 0.93 Identities = 30/133 (22%), Positives = 55/133 (41%), Gaps = 24/133 (18%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFET----YDVHG-----DMPAVPPAVIESIR 380 + ++PGDGIGP + ++++ + F YD+ G A+ IE Sbjct: 8 IAVLPGDGIGPEIIQEAYKIIDVLQKKFSFNVKMHEYDIGGISIDKHGTALTQETIEGCE 67 Query: 381 RNKVCLKGGLATPVGGGVSSLN-------MQLRKELDLFASLVNCANVPGL----PTRH- 524 + L G + + + ++LRK +LFA++ C L P ++ Sbjct: 68 NSDAILFGSVGGSKWDHLPEIEKPEKAGLLKLRKHFNLFANIRPCKLSQHLLDISPLKNS 127 Query: 525 ---KNVDIVVIRE 554 K +D++ IRE Sbjct: 128 IIKKGIDLICIRE 140
>LEU3_BRANA (P29102) 3-isopropylmalate dehydrogenase, chloroplast precursor (EC| 1.1.1.85) (Beta-IPM dehydrogenase) (IMDH) (3-IPM-DH) Length = 406 Score = 32.3 bits (72), Expect = 0.93 Identities = 35/137 (25%), Positives = 55/137 (40%), Gaps = 28/137 (20%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEA-----------MHAPVYFETYDVHGDMPAVPPAVIES 374 +TL+PGDGIGP V + V++ PV D+ G +P + + Sbjct: 46 ITLLPGDGIGPEVISIAKNVLQQAGSLEGLEFSFQEMPVGGAALDLVG--VPLPEETVSA 103 Query: 375 IRRNKVCLKGGLATPVGGGVSSLN----------MQLRKELDLFASLVNCANVPGLPTRH 524 + + L G +GG N +QLR L +FA+L +P L Sbjct: 104 AKESDAVLLGA----IGGYKWDKNEKHLKPETGLLQLRAGLKVFANLRPATVLPQLVDAS 159 Query: 525 -------KNVDIVVIRE 554 + VD++V+RE Sbjct: 160 TLKREVAEGVDLMVVRE 176
>LEU3_STAS1 (Q49Z13) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 346 Score = 32.3 bits (72), Expect = 0.93 Identities = 31/129 (24%), Positives = 55/129 (42%), Gaps = 20/129 (15%) Frame = +3 Query: 228 VTLIPGDGIGP-LVTGAVE---QVMEAMHAPVYFETYDVHG-----DMPAVPPAVIESIR 380 + +PGDGIGP ++ G++E Q+ + H E++D G +P + + + + Sbjct: 5 IVALPGDGIGPEILNGSLEILQQLSKEFHFEYELESHDFGGIAIDNHGKPLPDSTLNACK 64 Query: 381 RNKVCLKGGLATPVGGGVSSLNMQ----LRKELDLFASLVNCANVPGL-------PTRHK 527 L G + P ++ Q +RK L LFA++ G R Sbjct: 65 NADAILLGAVGGPKWTDPNNRPEQGLLGIRKALGLFANIRPTTVTNGTSHLSPIKEERVA 124 Query: 528 NVDIVVIRE 554 N D +++RE Sbjct: 125 NTDFILVRE 133
>LEU3_VIBF1 (Q5E857) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 32.0 bits (71), Expect = 1.2 Identities = 36/133 (27%), Positives = 57/133 (42%), Gaps = 24/133 (18%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAM---HAPVYF-ETYDVHG-----DMPAVPPAVIESIR 380 + ++PGDGIGP V +V++A+ HA + E +DV G +P + ++ Sbjct: 8 IAVLPGDGIGPEVMEQAHKVLDAIEKKHAISFSREQHDVGGIAIDNHGCPLPESTVKGCE 67 Query: 381 RNKVCLKGGLATPVGGGVSSLN-------MQLRKELDLFASLVNCANVPGL----PTR-- 521 + L G + P + + + LRK LF +L GL P R Sbjct: 68 ESDAVLFGSVGGPKWEHLPPNDQPERGALLPLRKHFQLFCNLRPAQIHKGLENFSPLRAD 127 Query: 522 --HKNVDIVVIRE 554 + DIVV+RE Sbjct: 128 ISERGFDIVVVRE 140
>LEU3_ERWCT (Q6D0G7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 32.0 bits (71), Expect = 1.2 Identities = 34/133 (25%), Positives = 52/133 (39%), Gaps = 24/133 (18%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMH----APVYFETYDVHG-----DMPAVPPAVIESIR 380 + ++PGDGIGP V +V++A+ + YDV G +P A + Sbjct: 7 IAVLPGDGIGPEVMAQAHKVLDAVRQRFGIRITTSEYDVGGIAIDRQGTPLPQATVAGCE 66 Query: 381 RNKVCLKGGLATPVGGGVSSLN-------MQLRKELDLFASLVNCANVPGL----PTRH- 524 + L G + P + + LRK LF++L GL P R Sbjct: 67 QADAILFGSVGGPKWEHLPPAEQPERGALLPLRKHFKLFSNLRPARLYQGLEAFCPLRSD 126 Query: 525 ---KNVDIVVIRE 554 K DI+ +RE Sbjct: 127 IAAKGFDILCVRE 139
>MYO15_HUMAN (Q9UKN7) Myosin-15 (Myosin XV) (Unconventional myosin-15)| Length = 3530 Score = 32.0 bits (71), Expect = 1.2 Identities = 15/37 (40%), Positives = 21/37 (56%) Frame = -1 Query: 271 PVTRGPMPSPGMSVTGRGVPSPGRGM*VTVRRAPPPW 161 P + GP P+P +S G+P P ++RR PPPW Sbjct: 669 PPSSGPPPAPPLSPALSGLPRPASPY-GSLRRHPPPW 704
>LEU3_OCEIH (Q8EN68) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 366 Score = 32.0 bits (71), Expect = 1.2 Identities = 33/131 (25%), Positives = 59/131 (45%), Gaps = 22/131 (16%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHAP----VYFETYDVHGDM-----PAVPPAVIESIR 380 + L+PGDGIG + + +QV+ A+ + FE + + G +P +++ Sbjct: 5 IILLPGDGIGREIIDSAKQVLTAIASEYNHRFTFEEHAIGGSAIDEYGTPLPDKTVDACS 64 Query: 381 RNKVCLKGGLATPV-GGGVSSLN-----MQLRKELDLFASLVNCANVPGL----PTRHKN 530 + L G + P S L + +RK+L LFA+L + L P + + Sbjct: 65 KADAILLGAVGGPKWDANPSHLRPEKGLLGIRKQLGLFANLRPVKTISSLLYASPLKEEI 124 Query: 531 V---DIVVIRE 554 V D+++IRE Sbjct: 125 VSQADMLIIRE 135
>LEU3_SILPO (Q5LWZ5) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 367 Score = 32.0 bits (71), Expect = 1.2 Identities = 29/101 (28%), Positives = 48/101 (47%), Gaps = 17/101 (16%) Frame = +3 Query: 234 LIPGDGIGPLVTGAVEQVM-----------EAMHAPVYFETYDVHGDMPAVPPAVIESIR 380 ++PGDGIGP V V +++ + V YDVHG +P + ++ Sbjct: 8 ILPGDGIGPEVMAEVRKIIGWFGDKRGLNFDVSEDLVGGAAYDVHG-VPLADETMAKAQE 66 Query: 381 RNKVCLKGGLATPVGGGVS-SLN-----MQLRKELDLFASL 485 + V L G + P + S+ ++LRKE+DLF++L Sbjct: 67 ADAVLL-GAVGGPKYDDLDFSVKPERGLLRLRKEMDLFSNL 106
>LEU3_PSEU2 (Q4ZUZ4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 360 Score = 32.0 bits (71), Expect = 1.2 Identities = 36/133 (27%), Positives = 58/133 (43%), Gaps = 22/133 (16%) Frame = +3 Query: 222 RPVTLIPGDGIGPLVTGAVEQVMEAMHA--PVYFE-TYDVHG----DMPAVPPA--VIES 374 + + ++PGDGIGP + +V+E + + FE T+DV G D VP A +E Sbjct: 3 KQILILPGDGIGPEIMTEAVKVLELANEKYQLGFELTHDVIGGAAIDKHGVPLADETLER 62 Query: 375 IRRNKVCLKGGLATPVGGGV------SSLNMQLRKELDLFASLVNCANVPGL-------P 515 R L G + P + +++R +L LF +L P L P Sbjct: 63 ARAADAVLLGAVGGPKWDTIERDIRPERGLLKIRSQLGLFGNLRPAILYPQLADASSLKP 122 Query: 516 TRHKNVDIVVIRE 554 +DI+++RE Sbjct: 123 EIVAGLDIMIVRE 135
>LEU3_AQUAE (O66607) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 364 Score = 32.0 bits (71), Expect = 1.2 Identities = 32/133 (24%), Positives = 58/133 (43%), Gaps = 24/133 (18%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAM-----------HAPVYFETYDVHGDMPAVPPAVIES 374 + ++ GDGIGP + +V++ + + E D GD +P ++ Sbjct: 6 IAVLKGDGIGPEIVEQALRVLDKIGEIYGVEFEYREGLIGGEAIDKTGD--PLPEETLKI 63 Query: 375 IRRNKVCLKGGLATPVGGGVSSLN------MQLRKELDLFASL----VNCANVPGLPTRH 524 + + L G + P + + +++RKELDL+A+L V A + P + Sbjct: 64 CKESDAILLGAVGGPKWDNLPTDKRPEKGLLRIRKELDLYANLRPAKVWDALISSSPLKE 123 Query: 525 ---KNVDIVVIRE 554 K D++VIRE Sbjct: 124 EVVKGTDMIVIRE 136
>LEU3_STRCO (O86504) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 347 Score = 31.6 bits (70), Expect = 1.6 Identities = 33/123 (26%), Positives = 54/123 (43%), Gaps = 14/123 (11%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEA-MHAPVYFETYD-------VHGDMPAVPPAVIESIRR 383 + +IPGDGIG V +V+ A + V ET + H + A +++++ Sbjct: 7 LAVIPGDGIGQEVVAEGLKVLSAVLPQDVKLETKEFDFGARRYHATGETLTDADLDALKA 66 Query: 384 NKVCLKGGLATP-VGGGV--SSLNMQLRKELDLFASLVNCANVPGLPT---RHKNVDIVV 545 + L G + P V GV ++LR D +L +PG+ T +D VV Sbjct: 67 HDAILLGAIGDPSVPSGVLERGFLLKLRFAFDHHVNLRPSKLLPGVATPLAGQPEIDFVV 126 Query: 546 IRE 554 +RE Sbjct: 127 VRE 129
>LEU3_YERPS (Q66EM2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 31.6 bits (70), Expect = 1.6 Identities = 33/133 (24%), Positives = 52/133 (39%), Gaps = 24/133 (18%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMH----APVYFETYDVHGDM-----PAVPPAVIESIR 380 + ++PGDGIGP V +V++A+ + YDV G +P A + Sbjct: 7 IAVLPGDGIGPEVMAQASKVLDAVRQRFGLKISTSVYDVGGAAIDRHGSPLPAATVAGCE 66 Query: 381 RNKVCLKGGLATPVGGGVSSLN-------MQLRKELDLFASLVNCANVPGL----PTRH- 524 + L G + P + + LRK LF++L GL P R Sbjct: 67 QADAILFGSVGGPKWEHLPPAEQPERGALLPLRKHFKLFSNLRPARLYQGLEDFCPLRSD 126 Query: 525 ---KNVDIVVIRE 554 + DI+ +RE Sbjct: 127 IAARGFDILCVRE 139
>LEU3_YERPE (Q8ZIG9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 31.6 bits (70), Expect = 1.6 Identities = 33/133 (24%), Positives = 52/133 (39%), Gaps = 24/133 (18%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMH----APVYFETYDVHGDM-----PAVPPAVIESIR 380 + ++PGDGIGP V +V++A+ + YDV G +P A + Sbjct: 7 IAVLPGDGIGPEVMAQASKVLDAVRQRFGLKISTSVYDVGGAAIDRHGSPLPAATVAGCE 66 Query: 381 RNKVCLKGGLATPVGGGVSSLN-------MQLRKELDLFASLVNCANVPGL----PTRH- 524 + L G + P + + LRK LF++L GL P R Sbjct: 67 QADAILFGSVGGPKWEHLPPAEQPERGALLPLRKHFKLFSNLRPARLYQGLEDFCPLRSD 126 Query: 525 ---KNVDIVVIRE 554 + DI+ +RE Sbjct: 127 IAARGFDILCVRE 139
>LEU3_BACHD (Q9K8E9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 31.6 bits (70), Expect = 1.6 Identities = 12/26 (46%), Positives = 20/26 (76%) Frame = +3 Query: 222 RPVTLIPGDGIGPLVTGAVEQVMEAM 299 + + ++PGDGIGP VT A +V++A+ Sbjct: 3 KQIAVLPGDGIGPEVTDAAIEVLQAV 28
>LEU3_GLOVI (Q7NFH4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 362 Score = 31.6 bits (70), Expect = 1.6 Identities = 34/133 (25%), Positives = 54/133 (40%), Gaps = 24/133 (18%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAM-----------HAPVYFETYDVHGDMPAVPPAVIES 374 + ++PGDGIG + ++EA AP+ D G+ +P A +E Sbjct: 7 IAVLPGDGIGTEIVQVGVAMLEAAARRFDFAFDFEEAPIGGAAIDATGE--PLPAATLEL 64 Query: 375 IRRNKVCLKGGLATPVGGGVSS------LNMQLRKELDLFASLVNCANVPGL-------P 515 + + G + P + S + LR L LFA+L +P L P Sbjct: 65 CKASDAVFLGAVGGPQWDTLPSDKRPEKALLGLRAGLGLFANLRPARILPQLVAASALKP 124 Query: 516 TRHKNVDIVVIRE 554 + VDI+V+RE Sbjct: 125 EVVEGVDILVVRE 137
>LEU3_THETN (Q8RDK0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 355 Score = 31.6 bits (70), Expect = 1.6 Identities = 34/134 (25%), Positives = 55/134 (41%), Gaps = 25/134 (18%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHA-----------PVYFETYDVHGDMPAVPPAVIES 374 + ++PGDGIGP V +V++A+ P E D +G+ P Sbjct: 4 IAVLPGDGIGPEVIEEGLKVLKAVEEKYGLRFDIKKYPFGGEAIDKYGE--PYPEETRNG 61 Query: 375 IRRNKVCLKGGLATPVGGGVSSLN------MQLRKELDLFASLVNCANVPGL----PTRH 524 + L G + P G+ + LRK L ++A+L P L P ++ Sbjct: 62 CLSSDAVLLGAVGGPKWDGLEGDKRPEAGLLALRKSLGVYANLRPAVLYPSLKDASPLKN 121 Query: 525 ----KNVDIVVIRE 554 K +DI+V+RE Sbjct: 122 ELLEKGLDILVVRE 135
>LEU32_ARATH (P93832) 3-isopropylmalate dehydrogenase 2, chloroplast precursor| (EC 1.1.1.85) (Beta-IPM dehydrogenase 2) (IMDH 2) (3-IPM-DH 2) Length = 405 Score = 31.6 bits (70), Expect = 1.6 Identities = 34/138 (24%), Positives = 55/138 (39%), Gaps = 29/138 (21%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEA-----------MHAPVYFETYDVHGDMPAVPPAVIES 374 +TL+PGDGIGP V + V++ P+ D+ G +P I + Sbjct: 45 ITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVG--VPLPEETISA 102 Query: 375 IRRNKVCLKGGLATPVGGGVSSLN-----------MQLRKELDLFASLVNCANVPGLPTR 521 + + L G + GG N +Q+R L +FA+L +P L Sbjct: 103 AKESDAVLLGAI-----GGYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATVLPQLVDA 157 Query: 522 H-------KNVDIVVIRE 554 + VD++V+RE Sbjct: 158 STLKREVAEGVDLMVVRE 175
>LEU3_WOLSU (Q7M886) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 358 Score = 31.2 bits (69), Expect = 2.1 Identities = 38/131 (29%), Positives = 57/131 (43%), Gaps = 22/131 (16%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFE----TYDVHG---DMPAV--PPAVIESIR 380 + +I GDGIGP + ++V++A+ FE Y + G D V P IE Sbjct: 6 IAIIKGDGIGPEIVDEAKKVLDAISYSHGFELSYHDYLMGGIAVDRAGVPLPDETIEGCL 65 Query: 381 RNKVCLKGGL------ATPVGGGVSSLNMQLRKELDLFASLVNCANVPGL-------PTR 521 R L G + + P S ++LRK L++FA+L L + Sbjct: 66 RADAVLFGAIGGEKWDSLPRELRPESGLLKLRKSLEIFANLRPTVVYDELIEASTLKESV 125 Query: 522 HKNVDIVVIRE 554 K VDI+V+RE Sbjct: 126 IKGVDILVVRE 136
>NIT2_NEUCR (P19212) Nitrogen catabolic enzyme regulatory protein| Length = 1036 Score = 31.2 bits (69), Expect = 2.1 Identities = 31/109 (28%), Positives = 45/109 (41%), Gaps = 9/109 (8%) Frame = -1 Query: 496 AQLTREAKRSSSLRSCMLREETPPPTGVARPPLRQTL----LRRMDS-----MTAGGTAG 344 A ++ A+++S+L S PP VA PP +Q + + +S + G TAG Sbjct: 811 ASMSAAARKNSTL-SITSNANNQPPAQVATPPAQQQVRASSVNESESPASGPASGGNTAG 869 Query: 343 MSPWTSYVSK*TGACMASMTCSTAPVTRGPMPSPGMSVTGRGVPSPGRG 197 +P TSY T ST+ G P S + P PG G Sbjct: 870 STP-TSY---------HGSTGSTSGAVGGKSVIPIASAPPKSAPGPGAG 908
>LEU3_XANOR (Q5H4C7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 357 Score = 31.2 bits (69), Expect = 2.1 Identities = 33/135 (24%), Positives = 57/135 (42%), Gaps = 24/135 (17%) Frame = +3 Query: 222 RPVTLIPGDGIGPLVTGAVEQVMEAMHAP-------VYFE----TYDVHGDMPAVPPAVI 368 + + ++PGDGIGP + +V++ + VY E YD +G + + Sbjct: 3 KQILILPGDGIGPEIMAEAVKVLQRIDTQHGLGFELVYDELGGAAYDKYGS--PLADETL 60 Query: 369 ESIRRNKVCLKGGLATPVGGGVS-SLN-----MQLRKELDLFASLVNCANVPGL------ 512 E R L G + P + SL +++R +L LFA+L P L Sbjct: 61 ERARAADAVLLGAVGGPQWDTIDPSLRPERGLLKIRSQLGLFANLRPALLYPQLADASTL 120 Query: 513 -PTRHKNVDIVVIRE 554 P +D++++RE Sbjct: 121 KPEVVAGLDLLILRE 135
>LEU3_XANAC (Q8PH05) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 357 Score = 31.2 bits (69), Expect = 2.1 Identities = 32/135 (23%), Positives = 56/135 (41%), Gaps = 24/135 (17%) Frame = +3 Query: 222 RPVTLIPGDGIGPLVTGAVEQVMEAMHAP-------VYFE----TYDVHGDMPAVPPAVI 368 + + ++PGDGIGP + +V++ + A VY E YD +G + + Sbjct: 3 KQILILPGDGIGPEIMAEAVKVLKRIDAQHGLGFQLVYDELGGTAYDKYGS--PLADETL 60 Query: 369 ESIRRNKVCLKGGLATPVGGGVSSL------NMQLRKELDLFASLVNCANVPGL------ 512 E R L G + P + +++R +L LFA+L P L Sbjct: 61 ERARGADAVLLGAVGGPQWDTIDPALRPERGLLKIRSQLGLFANLRPALLYPQLADASTL 120 Query: 513 -PTRHKNVDIVVIRE 554 P +D++++RE Sbjct: 121 KPEVVAGLDLLILRE 135
>LEU3_PELCD (Q3A3B2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 365 Score = 31.2 bits (69), Expect = 2.1 Identities = 32/133 (24%), Positives = 54/133 (40%), Gaps = 24/133 (18%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHA--PVYFETY-------DVHGDMPAVPPAVIESIR 380 + ++PGDGIGP + +V++A+ V FE + D A+P A +E + Sbjct: 7 LAVLPGDGIGPEIMAEAMKVLDAVEQKFQVRFERQFANVGGAAIDRDGKALPDATVEICQ 66 Query: 381 RNKVCLKGGLATPVGGGVSSLN-------MQLRKELDLFASLVNCANVPGLPTRHK---- 527 + L G + P + + + LR+ LF +L P L + Sbjct: 67 ASDAILFGSVGGPKWDTLPAEERPERGALLPLRRIFGLFCNLRPAIVFPALTSASSLKEE 126 Query: 528 ----NVDIVVIRE 554 DI+V+RE Sbjct: 127 VIAGGFDILVVRE 139
>LEU3_LEIXX (Q6AEP6) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 357 Score = 31.2 bits (69), Expect = 2.1 Identities = 36/130 (27%), Positives = 57/130 (43%), Gaps = 21/130 (16%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHA-------PVYF----ETYDVHGDMPAVPPAVIES 374 + +IPGDGIGP V + ++A+ A YF + Y GD+ + + + Sbjct: 7 LVVIPGDGIGPEVIAEAVKALDAVTAGSGLAFQKTYFSLGADRYLATGDV--LTDDDLAA 64 Query: 375 IRRNKVCLKGGLATPVG----GGVS---SLNMQLRKELDLFASLVNCANVPGLPT---RH 524 IR + L G + G G + L ++LR LD + +L PG+ + Sbjct: 65 IRGHDAILLGAVGGRPGDPRLAGANVERGLLLRLRFSLDHYVNLRPTTLFPGIASPLAAP 124 Query: 525 KNVDIVVIRE 554 VD VV+RE Sbjct: 125 GEVDFVVVRE 134
>LEU3_RALEJ (Q46YW0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 355 Score = 31.2 bits (69), Expect = 2.1 Identities = 30/127 (23%), Positives = 50/127 (39%), Gaps = 18/127 (14%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHG-----DMPAVPPAVIESIRRNKV 392 + ++PGDGIGP + +V+ A+ ET V G + +P ++ + Sbjct: 3 IAVLPGDGIGPEIVAEAVKVLNALDEKFEMETAPVGGAGYEAEGHPLPENTLKLAKEADA 62 Query: 393 CLKGGLATPVGGGV------SSLNMQLRKELDLFASLVNCANVPGL-------PTRHKNV 533 L G + + + LRK L LFA+ P L P + Sbjct: 63 ILFGAVGDWKYDSLERALRPEQAILGLRKHLQLFANFRPAICYPELTGASSLKPELVAGL 122 Query: 534 DIVVIRE 554 DI+++RE Sbjct: 123 DILIVRE 129
>KDSB_VIBPA (Q87R14) 3-deoxy-manno-octulosonate cytidylyltransferase (EC| 2.7.7.38) (CMP-KDO synthetase) (CMP-2-keto-3-deoxyoctulosonic acid synthetase) (CKS) Length = 251 Score = 31.2 bits (69), Expect = 2.1 Identities = 16/50 (32%), Positives = 23/50 (46%) Frame = +3 Query: 267 TGAVEQVMEAMHAPVYFETYDVHGDMPAVPPAVIESIRRNKVCLKGGLAT 416 T + +V+E M P +V GD P VPP +I + N +AT Sbjct: 76 TERLAEVVEKMAIPADHIIVNVQGDEPLVPPVIIRQVADNLAASDAPMAT 125
>KDSB_VIBCH (Q9KQX2) 3-deoxy-manno-octulosonate cytidylyltransferase (EC| 2.7.7.38) (CMP-KDO synthetase) (CMP-2-keto-3-deoxyoctulosonic acid synthetase) (CKS) Length = 252 Score = 31.2 bits (69), Expect = 2.1 Identities = 15/50 (30%), Positives = 23/50 (46%) Frame = +3 Query: 267 TGAVEQVMEAMHAPVYFETYDVHGDMPAVPPAVIESIRRNKVCLKGGLAT 416 T + +V+ M P +V GD P +PPA+I + N +AT Sbjct: 76 TERLAEVVAKMAIPADHIVVNVQGDEPLIPPAIIRQVADNLAACSAPMAT 125
>NMDE3_HUMAN (Q14957) Glutamate [NMDA] receptor subunit epsilon 3 precursor| (N-methyl D-aspartate receptor subtype 2C) (NR2C) (NMDAR2C) Length = 1233 Score = 30.8 bits (68), Expect = 2.7 Identities = 20/41 (48%), Positives = 21/41 (51%) Frame = -1 Query: 274 APVTRGPMPSPGMSVTGRGVPSPGRGM*VTVRRAPPPWPGR 152 +P P P P S TG G P GR VRRAP P PGR Sbjct: 943 SPCLPTPDPPPEPSPTGWGPPDGGRA--ALVRRAPQP-PGR 980
>LEU3_STAES (Q8CNL2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 347 Score = 30.8 bits (68), Expect = 2.7 Identities = 32/129 (24%), Positives = 58/129 (44%), Gaps = 20/129 (15%) Frame = +3 Query: 228 VTLIPGDGIGP-LVTGAVE---QVMEAMHAPVYFETYDVHG---DMPAVP--PAVIESIR 380 + +PGDGIGP +++G +E + E H + E++ G D P ++S + Sbjct: 5 IVALPGDGIGPEILSGTLELLKLISEKYHFEYHLESHHFGGVSIDYYGTPLTNETLQSCK 64 Query: 381 RNKVCLKGGLATPVGGGVSSLN----MQLRKELDLFASLVNCANVPGL----PTRH---K 527 L G + P ++ ++LRK L+LFA++ G P + + Sbjct: 65 NADAILLGAIGGPKWTDPNNRPEHGLLKLRKSLNLFANIRPTFVTKGASHLSPLKQDIVE 124 Query: 528 NVDIVVIRE 554 D+V++RE Sbjct: 125 GTDLVIVRE 133
>LEU3_STAEQ (Q5HMF8) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 347 Score = 30.8 bits (68), Expect = 2.7 Identities = 32/129 (24%), Positives = 58/129 (44%), Gaps = 20/129 (15%) Frame = +3 Query: 228 VTLIPGDGIGP-LVTGAVE---QVMEAMHAPVYFETYDVHG---DMPAVP--PAVIESIR 380 + +PGDGIGP +++G +E + E H + E++ G D P ++S + Sbjct: 5 IVALPGDGIGPEILSGTLELLKLISEKYHFEYHLESHHFGGVSIDYYGTPLTNETLQSCK 64 Query: 381 RNKVCLKGGLATPVGGGVSSLN----MQLRKELDLFASLVNCANVPGL----PTRH---K 527 L G + P ++ ++LRK L+LFA++ G P + + Sbjct: 65 NADAILLGAIGGPKWTDPNNRPEHGLLKLRKSLNLFANIRPTFVTKGASHLSPLKQDIVE 124 Query: 528 NVDIVVIRE 554 D+V++RE Sbjct: 125 GTDLVIVRE 133
>LEU3_STAAS (Q6G7Q0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 348 Score = 30.8 bits (68), Expect = 2.7 Identities = 28/129 (21%), Positives = 52/129 (40%), Gaps = 20/129 (15%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHGDM---------PAVPPAVIESIR 380 + +PGDGIGP + ++E + F H + + + + + Sbjct: 5 IVALPGDGIGPEILNGSLSLLEIISNKYNFNYQIEHHEFGGASIDTFGEPLTEKTLNACK 64 Query: 381 RNKVCLKGGLATPVGGGVSSLN----MQLRKELDLFASLVNCANVPGLPT-------RHK 527 R L G + P ++ ++LRK L+LFA++ V G + R + Sbjct: 65 RADAILLGAIGGPKWTDPNNRPEQGLLKLRKSLNLFANIRPTTVVKGASSLSPLKEERVE 124 Query: 528 NVDIVVIRE 554 D+V++RE Sbjct: 125 GTDLVIVRE 133
>LEU3_STAAR (Q6GF15) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 348 Score = 30.8 bits (68), Expect = 2.7 Identities = 28/129 (21%), Positives = 52/129 (40%), Gaps = 20/129 (15%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHGDM---------PAVPPAVIESIR 380 + +PGDGIGP + ++E + F H + + + + + Sbjct: 5 IVALPGDGIGPEILNGSLSLLEIISNKYNFNYQIEHHEFGGASIDTFGEPLTEKTLNACK 64 Query: 381 RNKVCLKGGLATPVGGGVSSLN----MQLRKELDLFASLVNCANVPGLPT-------RHK 527 R L G + P ++ ++LRK L+LFA++ V G + R + Sbjct: 65 RADAILLGAIGGPKWTDPNNRPEQGLLKLRKSLNLFANIRPTTVVKGASSLSPLKAERVE 124 Query: 528 NVDIVVIRE 554 D+V++RE Sbjct: 125 GTDLVIVRE 133
>LEU3_STAAN (P65101) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 348 Score = 30.8 bits (68), Expect = 2.7 Identities = 28/129 (21%), Positives = 52/129 (40%), Gaps = 20/129 (15%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHGDM---------PAVPPAVIESIR 380 + +PGDGIGP + ++E + F H + + + + + Sbjct: 5 IVALPGDGIGPEILNGSLSLLEIISNKYNFNYQIEHHEFGGASIDTFGEPLTEKTLNACK 64 Query: 381 RNKVCLKGGLATPVGGGVSSLN----MQLRKELDLFASLVNCANVPGLPT-------RHK 527 R L G + P ++ ++LRK L+LFA++ V G + R + Sbjct: 65 RADAILLGAIGGPKWTDPNNRPEQGLLKLRKSLNLFANIRPTTVVKGASSLSPLKEERVE 124 Query: 528 NVDIVVIRE 554 D+V++RE Sbjct: 125 GTDLVIVRE 133
>LEU3_STAAM (P65100) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 348 Score = 30.8 bits (68), Expect = 2.7 Identities = 28/129 (21%), Positives = 52/129 (40%), Gaps = 20/129 (15%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHGDM---------PAVPPAVIESIR 380 + +PGDGIGP + ++E + F H + + + + + Sbjct: 5 IVALPGDGIGPEILNGSLSLLEIISNKYNFNYQIEHHEFGGASIDTFGEPLTEKTLNACK 64 Query: 381 RNKVCLKGGLATPVGGGVSSLN----MQLRKELDLFASLVNCANVPGLPT-------RHK 527 R L G + P ++ ++LRK L+LFA++ V G + R + Sbjct: 65 RADAILLGAIGGPKWTDPNNRPEQGLLKLRKSLNLFANIRPTTVVKGASSLSPLKEERVE 124 Query: 528 NVDIVVIRE 554 D+V++RE Sbjct: 125 GTDLVIVRE 133
>LEU3_VIBPA (Q87SS8) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 30.8 bits (68), Expect = 2.7 Identities = 35/135 (25%), Positives = 55/135 (40%), Gaps = 26/135 (19%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHAP--VYFE---------TYDVHGDMPAVPPAVIES 374 + ++PGDGIGP V +V++A+ + FE D HG +P + + + Sbjct: 8 IAVLPGDGIGPEVMAQAHKVLDAIEQKHGISFEREEHDVGGIAIDNHG--CPLPESTVTA 65 Query: 375 IRRNKVCLKGGLATPVGGGVSSLN-------MQLRKELDLFASLVNCANVPGL----PTR 521 + L G + P + + + LRK LF +L GL P R Sbjct: 66 CEESDAVLFGSVGGPKWEHLPPNDQPERGALLPLRKHFQLFCNLRPAQIHAGLEAFSPLR 125 Query: 522 ----HKNVDIVVIRE 554 + DIVV+RE Sbjct: 126 ADISGRGFDIVVVRE 140
>LEU3_PHOPR (Q6LV25) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 362 Score = 30.8 bits (68), Expect = 2.7 Identities = 32/133 (24%), Positives = 53/133 (39%), Gaps = 24/133 (18%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHGDMPAV---------PPAVIESIR 380 + ++PGDGIGP V +V++A+ F D+ + P + ++ Sbjct: 7 IAVLPGDGIGPEVMLQAHKVLDAVEEKFGFTLERSEHDVGGIAIDNHGCPLPESTMKGCE 66 Query: 381 RNKVCLKGGLATPVGGGVSSLN-------MQLRKELDLFASLVNCANVPGL----PTR-- 521 + L G + P ++ + + LRK LF +L GL P R Sbjct: 67 ESDAILFGSVGGPKWEHLAPNDQPERGALLPLRKHFQLFCNLRPAQIHSGLEGFSPLRAD 126 Query: 522 --HKNVDIVVIRE 554 + DIVV+RE Sbjct: 127 ISERGFDIVVVRE 139
>LEU3_COLP3 (Q47WG3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 362 Score = 30.8 bits (68), Expect = 2.7 Identities = 31/135 (22%), Positives = 54/135 (40%), Gaps = 26/135 (19%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFE----TYDV-------HGDMPAVPPAVIES 374 + ++ GDGIGP V ++V+ + + FE YD+ HG+ A+P + + Sbjct: 4 IAILAGDGIGPEVMVEAKKVLNTVASKFDFEITTQDYDIGGAAIDNHGN--ALPDSTMAG 61 Query: 375 IRRNKVCLKGGLATPVGGGVSSLN-------MQLRKELDLFASLVNCANVPGLPT----- 518 + L G + P + + LR DLF ++ P L + Sbjct: 62 CIESDAILFGSVGGPKWANLPPTEQPERCALLGLRSHFDLFCNMRPATLQPALSSLSTLR 121 Query: 519 ---RHKNVDIVVIRE 554 + D++VIRE Sbjct: 122 SDISEQGFDVLVIRE 136
>LEU3_PSESM (Q884C0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 360 Score = 30.8 bits (68), Expect = 2.7 Identities = 35/133 (26%), Positives = 58/133 (43%), Gaps = 22/133 (16%) Frame = +3 Query: 222 RPVTLIPGDGIGPLVTGAVEQVMEAMHA--PVYFE-TYDVHG----DMPAVPPA--VIES 374 + + ++PGDGIGP + +V+E + + FE T+DV G D VP A ++ Sbjct: 3 KQILILPGDGIGPEIMTEAVKVLELANQKYQLGFELTHDVIGGAAIDKHGVPLADETLDR 62 Query: 375 IRRNKVCLKGGLATPVGGGV------SSLNMQLRKELDLFASLVNCANVPGL-------P 515 R L G + P + +++R +L LF +L P L P Sbjct: 63 ARAADAVLLGAVGGPKWDTIERDIRPERGLLKIRSQLGLFGNLRPAILYPQLADASSLKP 122 Query: 516 TRHKNVDIVVIRE 554 +DI+++RE Sbjct: 123 EIVAGLDILIVRE 135
>LEU3_PSE14 (Q48K97) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 360 Score = 30.8 bits (68), Expect = 2.7 Identities = 35/133 (26%), Positives = 58/133 (43%), Gaps = 22/133 (16%) Frame = +3 Query: 222 RPVTLIPGDGIGPLVTGAVEQVMEAMHA--PVYFE-TYDVHG----DMPAVPPA--VIES 374 + + ++PGDGIGP + +V+E + + FE T+DV G D VP A ++ Sbjct: 3 KQILILPGDGIGPEIMTEAVKVLELANEKYQLGFELTHDVIGGAAIDKHGVPLADETLDR 62 Query: 375 IRRNKVCLKGGLATPVGGGV------SSLNMQLRKELDLFASLVNCANVPGL-------P 515 R L G + P + +++R +L LF +L P L P Sbjct: 63 ARAADAVLLGAVGGPKWDTIERDIRPERGLLKIRSQLGLFGNLRPAILYPQLADASSLKP 122 Query: 516 TRHKNVDIVVIRE 554 +DI+++RE Sbjct: 123 EIVAGLDILIVRE 135
>LRP11_HUMAN (Q86VZ4) Low-density lipoprotein receptor-related protein 11| precursor Length = 500 Score = 30.4 bits (67), Expect = 3.5 Identities = 21/78 (26%), Positives = 33/78 (42%), Gaps = 5/78 (6%) Frame = -1 Query: 442 REETPPPTGVARPPLRQTLLRRMDSMTAGGT-----AGMSPWTSYVSK*TGACMASMTCS 278 +E+ P P + ++R DS+ AG + A + W V+ AC + CS Sbjct: 86 QEDCPGPGSGGYSAMPDAIIRTKDSLAAGASFLRAPAAVRGWRQCVA----ACCSEPRCS 141 Query: 277 TAPVTRGPMPSPGMSVTG 224 A V P+P +V G Sbjct: 142 VAVVELPRRPAPPAAVLG 159
>LEU3_STAAW (Q8NVJ0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 348 Score = 30.4 bits (67), Expect = 3.5 Identities = 29/129 (22%), Positives = 53/129 (41%), Gaps = 20/129 (15%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHGDM---------PAVPPAVIESIR 380 + +PGDGIGP + ++E + F H + + + + + Sbjct: 5 IVALPGDGIGPEILNGSLSLLEIISNKYNFNYQIEHHEFGGASIDTFGEPLTEKTLNACK 64 Query: 381 RNKVCLKGGLATPVGGGVSSLN----MQLRKELDLFASLVNCANVPGL----PTRHKNV- 533 R L G + P ++ ++LRK L+LFA++ V G P + + V Sbjct: 65 RADAILLGAIGGPKWTDPNNRPEQGLLKLRKSLNLFANIRPTTVVKGASSLSPLKEERVE 124 Query: 534 --DIVVIRE 554 D+V++RE Sbjct: 125 GKDLVIVRE 133
>INO80_GIBZE (Q4IL82) Putative DNA helicase INO80 (EC 3.6.1.-)| Length = 1904 Score = 30.4 bits (67), Expect = 3.5 Identities = 30/98 (30%), Positives = 38/98 (38%) Frame = -1 Query: 457 RSCMLREETPPPTGVARPPLRQTLLRRMDSMTAGGTAGMSPWTSYVSK*TGACMASMTCS 278 RS + PP G PP +Q LL S+ G TA M+P T+ GA S Sbjct: 285 RSPLSHSHQNPPAGSLSPPGQQPLL-ASPSVRHGTTANMNPTTN------GASAIPPFKS 337 Query: 277 TAPVTRGPMPSPGMSVTGRGVPSPGRGM*VTVRRAPPP 164 P P+P S T R P + + AP P Sbjct: 338 DLAAPSPPKPAPS-STTSRANPMSFDSILSSSEPAPKP 374
>KDSB_YERPE (Q8ZGA4) 3-deoxy-manno-octulosonate cytidylyltransferase (EC| 2.7.7.38) (CMP-KDO synthetase) (CMP-2-keto-3-deoxyoctulosonic acid synthetase) (CKS) Length = 250 Score = 30.4 bits (67), Expect = 3.5 Identities = 14/43 (32%), Positives = 20/43 (46%), Gaps = 3/43 (6%) Frame = +3 Query: 327 DVHGDMPAVPPAVIESIRRNKVCLKGGLAT---PVGGGVSSLN 446 +V GD P VPP +I + N G+AT P+ + N Sbjct: 96 NVQGDEPLVPPVIIRQVADNLAACSAGMATLAVPIASSEEAFN 138
>SENP3_HUMAN (Q9H4L4) Sentrin-specific protease 3 (EC 3.4.22.-)| (Sentrin/SUMO-specific protease SENP3) (SUMO-1-specific protease 3) Length = 574 Score = 30.0 bits (66), Expect = 4.6 Identities = 15/38 (39%), Positives = 17/38 (44%) Frame = -1 Query: 256 PMPSPGMSVTGRGVPSPGRGM*VTVRRAPPPWPGRDGA 143 P P P + G P PG G V RR P P P D + Sbjct: 36 PPPKPRLKSGGGFGPDPGSGTTVPTRRLPAPRPSFDAS 73
>TEGU_EHV1B (P28955) Large tegument protein| Length = 3421 Score = 30.0 bits (66), Expect = 4.6 Identities = 16/42 (38%), Positives = 24/42 (57%) Frame = -1 Query: 553 SLMTTMSTFLCLVGRPGTLAQLTREAKRSSSLRSCMLREETP 428 SL+ ++ F+ L PG L QL ++A+RS+S L E P Sbjct: 953 SLLLPLAGFVGLRAAPGVLEQLAKDAQRSTSEELRNLMHEAP 994
>SPN90_HUMAN (Q9NZQ3) SH3 adapter protein SPIN90 (NCK-interacting protein with| SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (AF3p21) (Diaphanous protein-interacting protein) (Dia-interacting protein 1) Length = 722 Score = 30.0 bits (66), Expect = 4.6 Identities = 24/90 (26%), Positives = 36/90 (40%) Frame = -1 Query: 433 TPPPTGVARPPLRQTLLRRMDSMTAGGTAGMSPWTSYVSK*TGACMASMTCSTAPVTRGP 254 TPPP P+++ R +++ A G+ G + S + + S T T Sbjct: 181 TPPP------PVKR---RDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDTLYTSSS 231 Query: 253 MPSPGMSVTGRGVPSPGRGM*VTVRRAPPP 164 PG S + P P RG TV + PP Sbjct: 232 PSEPGSSCSPTPPPVPRRGTHTTVSQVQPP 261
>FBX41_HUMAN (Q8TF61) F-box only protein 41| Length = 874 Score = 30.0 bits (66), Expect = 4.6 Identities = 14/31 (45%), Positives = 16/31 (51%) Frame = -1 Query: 298 MASMTCSTAPVTRGPMPSPGMSVTGRGVPSP 206 +AS CST P GP P PG + PSP Sbjct: 162 VASSACSTPPPGPGPGPCPGPASASPASPSP 192
>IDH3B_PIG (P56472) Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial| (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) (Fragments) Length = 103 Score = 30.0 bits (66), Expect = 4.6 Identities = 11/18 (61%), Positives = 15/18 (83%) Frame = +3 Query: 225 PVTLIPGDGIGPLVTGAV 278 PVT++PGDG+GP + AV Sbjct: 16 PVTMLPGDGVGPELMAAV 33
>CENG1_HUMAN (Q99490) Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like,| ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase activating protein 2) (GGAP2) Length = 1192 Score = 29.6 bits (65), Expect = 6.0 Identities = 16/42 (38%), Positives = 20/42 (47%) Frame = -1 Query: 280 STAPVTRGPMPSPGMSVTGRGVPSPGRGM*VTVRRAPPPWPG 155 S P+T P PSP +VT PG +T+ PP PG Sbjct: 289 SPPPLTLPPTPSPATAVTAASAQPPGPAPPITLE---PPAPG 327
>MUC2_RAT (Q62635) Mucin-2 precursor (Intestinal mucin 2) (Fragment)| Length = 1513 Score = 29.6 bits (65), Expect = 6.0 Identities = 23/78 (29%), Positives = 33/78 (42%), Gaps = 2/78 (2%) Frame = -1 Query: 433 TPPPTGVARPPLRQTLLRRMDSMTAGGTAGMSPWTSYVSK*TGACMASMTCSTAPV--TR 260 T P T A P + + T+ T+ SP TS + T ++ + + +P T Sbjct: 1415 TSPLTSSATSPTTSHITSTVSPTTSPTTSTTSPTTSPTTSTTSPTTSTTSPTPSPTTSTT 1474 Query: 259 GPMPSPGMSVTGRGVPSP 206 P PSP S T PSP Sbjct: 1475 SPTPSPTTSTTS-PTPSP 1491
>LEU3_SYNEL (P59029) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 361 Score = 29.6 bits (65), Expect = 6.0 Identities = 37/135 (27%), Positives = 55/135 (40%), Gaps = 26/135 (19%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYD----------VHGDMPAVPPAVIESI 377 + ++ GDGIGP +T V+ A+ AP + +D + +P A + + Sbjct: 7 IAVLAGDGIGPEITAVALDVLRAI-APRFGLDFDFVPALVGGCAIDAVGEPLPAATLATC 65 Query: 378 RRNKVCLKGGLATPVGGGVSSLNMQLRKE---------LDLFASLVNCANVPGL------ 512 R++ L LA G SL LR E L LFA+L P L Sbjct: 66 RQSDAVL---LAAIGGTQWDSLPRHLRPETGLLALRSGLGLFANLRPAKIFPQLLHASSL 122 Query: 513 -PTRHKNVDIVVIRE 554 P VD++V+RE Sbjct: 123 KPEVIAGVDLMVVRE 137
>LEU3_XANCP (Q8P5L1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 357 Score = 29.6 bits (65), Expect = 6.0 Identities = 31/135 (22%), Positives = 54/135 (40%), Gaps = 24/135 (17%) Frame = +3 Query: 222 RPVTLIPGDGIGPLVTGAVEQVMEAMHAP-------VYFE----TYDVHGDMPAVPPAVI 368 + + ++PGDGIGP + +V+ + VY E YD +G + + Sbjct: 3 KQILILPGDGIGPEIMAEAVKVLTRIDTQHTLGVTLVYDELGGAAYDKYGS--PLADETL 60 Query: 369 ESIRRNKVCLKGGLATPVGGGVSSL------NMQLRKELDLFASLVNCANVPGL------ 512 E R L G + P + +++R +L LFA+L P L Sbjct: 61 ERARAADAVLLGAVGGPQWDTIDPALRPERGLLKIRSQLGLFANLRPALLYPQLADASTL 120 Query: 513 -PTRHKNVDIVVIRE 554 P +D++++RE Sbjct: 121 KPEVVSGLDLLILRE 135
>LEU3_XANC8 (Q4UYG2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 357 Score = 29.6 bits (65), Expect = 6.0 Identities = 31/135 (22%), Positives = 54/135 (40%), Gaps = 24/135 (17%) Frame = +3 Query: 222 RPVTLIPGDGIGPLVTGAVEQVMEAMHAP-------VYFE----TYDVHGDMPAVPPAVI 368 + + ++PGDGIGP + +V+ + VY E YD +G + + Sbjct: 3 KQILILPGDGIGPEIMAEAVKVLTRIDTQHTLGVTLVYDELGGAAYDKYGS--PLADETL 60 Query: 369 ESIRRNKVCLKGGLATPVGGGVSSL------NMQLRKELDLFASLVNCANVPGL------ 512 E R L G + P + +++R +L LFA+L P L Sbjct: 61 ERARAADAVLLGAVGGPQWDTIDPALRPERGLLKIRSQLGLFANLRPALLYPQLADASTL 120 Query: 513 -PTRHKNVDIVVIRE 554 P +D++++RE Sbjct: 121 KPEVVSGLDLLILRE 135
>LEU3_PROMA (Q7VC80) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 362 Score = 29.6 bits (65), Expect = 6.0 Identities = 33/134 (24%), Positives = 56/134 (41%), Gaps = 25/134 (18%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAM---HAPVY------FETYDVHGDMPAVPPAVIESIR 380 +TL+ GDGIGP ++ ++++ A+ H+ + F + +P + S + Sbjct: 6 ITLLTGDGIGPEISIVAKKILAALSEKHSITFTIEEKPFGGQAIELTGKPLPEDTLNSCK 65 Query: 381 RNKVCLKGGLATPVGGGVSSLNMQLRKE---LDLFASLVNCANVPGLPTRH--------- 524 + L + P L LR E L+L A L AN+ + R Sbjct: 66 ASDAVLLAAIGDP---KYDDLPRDLRPETGLLNLRAGLNLFANIRPIKIRQALISSSSLK 122 Query: 525 ----KNVDIVVIRE 554 K+VD+VV+RE Sbjct: 123 SEIIKDVDLVVVRE 136
>MED15_YEAST (P19659) RNA polymerase II mediator complex subunit 15 (Galactose| metabolism protein 11) (Basal expression activator protein 1) (Autonomous replication regulatory protein 3) (Defective silencing suppressor protein 4) (Ty insertion suppressor Length = 1081 Score = 29.6 bits (65), Expect = 6.0 Identities = 27/98 (27%), Positives = 42/98 (42%), Gaps = 8/98 (8%) Frame = -1 Query: 475 KRSSSLRSCMLREETP--PPTGVARPPLRQTLLRRMDSMTAGGTAGMSPWTSYVSK*TGA 302 K +SS+ E TP P + A P L +T+ +++ T T ++ S K + + Sbjct: 726 KNTSSMDFLNSMENTPKVPVSAAATPSLNKTINGKVNGRTKSNTIPVTSIPSTNKKLSIS 785 Query: 301 CMASM------TCSTAPVTRGPMPSPGMSVTGRGVPSP 206 AS +TA T PSP + T G P+P Sbjct: 786 NAASQQPTPRSASNTAKSTPNTNPSPLKTQTKNGTPNP 823
>LEU3_PSEF5 (Q4KF05) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 360 Score = 29.6 bits (65), Expect = 6.0 Identities = 34/133 (25%), Positives = 58/133 (43%), Gaps = 22/133 (16%) Frame = +3 Query: 222 RPVTLIPGDGIGPLVTGAVEQVMEAMH--APVYFE-TYDVHG----DMPAVPPA--VIES 374 + + ++PGDGIGP + +V+E + + FE ++DV G D VP A ++ Sbjct: 3 KQILILPGDGIGPEIMAEAVKVLELANDKYSLGFELSHDVIGGAAIDKHGVPLADETLDR 62 Query: 375 IRRNKVCLKGGLATPVGGGV------SSLNMQLRKELDLFASLVNCANVPGL-------P 515 R L G + P + +++R +L LF +L P L P Sbjct: 63 ARAADAVLLGAVGGPKWDKIERDIRPERGLLKIRAQLGLFGNLRPAILYPQLADASSLKP 122 Query: 516 TRHKNVDIVVIRE 554 +DI+++RE Sbjct: 123 EIVSGLDILIVRE 135
>LEU3_PSEAE (Q51375) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 360 Score = 29.6 bits (65), Expect = 6.0 Identities = 35/133 (26%), Positives = 58/133 (43%), Gaps = 22/133 (16%) Frame = +3 Query: 222 RPVTLIPGDGIGPLVTGAVEQVMEAMH--APVYFE-TYDVHG----DMPAVPPA--VIES 374 + + ++PGDGIGP + +V+E + + FE DV G D VP A ++ Sbjct: 3 KQILVLPGDGIGPEIMAEAVKVLELANDRFQLGFELAEDVIGGAAIDKHGVPLADQTLQR 62 Query: 375 IRRNKVCLKGGLATPVGGGV------SSLNMQLRKELDLFASLVNCANVPGL-------P 515 R+ L G + P + +++R +L LFA+L P L P Sbjct: 63 ARQADAVLLGAVGGPKWDRIERDIRPERGLLKIRSQLGLFANLRPAILYPQLAAASSLKP 122 Query: 516 TRHKNVDIVVIRE 554 +DI+++RE Sbjct: 123 EVVAGLDILIVRE 135
>LEU31_ARATH (Q9SA14) 3-isopropylmalate dehydrogenase 1, chloroplast precursor| (EC 1.1.1.85) (Beta-IPM dehydrogenase 1) (IMDH 1) (3-IPM-DH 1) Length = 406 Score = 29.6 bits (65), Expect = 6.0 Identities = 11/22 (50%), Positives = 16/22 (72%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVME 293 +TL+PGDGIGP V + V++ Sbjct: 46 ITLLPGDGIGPEVISVAKNVLQ 67
>GID_STRPN (Q97R84) tRNA uridine 5-carboxymethylaminomethyl modification| enzyme gid Length = 444 Score = 29.6 bits (65), Expect = 6.0 Identities = 27/99 (27%), Positives = 42/99 (42%), Gaps = 2/99 (2%) Frame = +3 Query: 216 TPRPVTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHGDMPAVPPAVIESIRRNKVC 395 T P +I GPL + A+ + + A++ F YD A P + +I +KV Sbjct: 124 TELPTDVITVIATGPLTSDALAEKIHALNDGAGFYFYDA-----AAPIIDVNTIDMSKVY 178 Query: 396 LKGGLATPVGGGVSSLNMQLRKE--LDLFASLVNCANVP 506 LK G + LN + K+ +D +LVN P Sbjct: 179 LKSRYDK---GEAAYLNAPMTKQEFMDFHEALVNAEEAP 214
>LEU3_PASMU (Q9CJN6) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 359 Score = 29.3 bits (64), Expect = 7.9 Identities = 32/133 (24%), Positives = 52/133 (39%), Gaps = 24/133 (18%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFE----TYDVHG-----DMPAVPPAVIESIR 380 + ++ GDGIGP + +V++ + F+ T+DV G +P A ++ Sbjct: 6 IAVLSGDGIGPEIIAEAIKVLDVVQQKYAFKLNYRTFDVGGIAIDNHGTPLPEATLKGCE 65 Query: 381 RNKVCLKGGLATPVGGGVSSLN-------MQLRKELDLFASLVNCANVPGL----PTR-- 521 + L G + P + + LRK LF +L GL P R Sbjct: 66 ESDAILFGSVGGPKWEHLPPAQQPERGALLPLRKHFALFCNLRPATLYKGLEKFCPLRAD 125 Query: 522 --HKNVDIVVIRE 554 K D+V +RE Sbjct: 126 ISAKGFDMVTVRE 138
>FA9_CHICK (Q804X6) Coagulation factor IX precursor (EC 3.4.21.22) (Christmas| factor) [Contains: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain] Length = 471 Score = 29.3 bits (64), Expect = 7.9 Identities = 21/75 (28%), Positives = 31/75 (41%), Gaps = 5/75 (6%) Frame = -1 Query: 436 ETPPPTGVARPPLRQTLLRRMDSMTAGG---TAGMSPWTSYV--SK*TGACMASMTCSTA 272 E PPP + P + + + D+ GG G PW ++ S+ G C S+ Sbjct: 212 EPPPPPTTSAAPAKIVPITKNDTRVVGGYDSVKGQLPWQVHLVDSRGLGFCGGSIINEKW 271 Query: 271 PVTRGPMPSPGMSVT 227 VT PG +VT Sbjct: 272 VVTAAHCLEPGDNVT 286
>LEU3_STAAC (Q5HEE3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 348 Score = 29.3 bits (64), Expect = 7.9 Identities = 27/129 (20%), Positives = 51/129 (39%), Gaps = 20/129 (15%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAMHAPVYFETYDVHGDM---------PAVPPAVIESIR 380 + +PGDGIGP + ++E + F H + + + + + Sbjct: 5 IVALPGDGIGPEILNGSLSLLEIISNKYNFNYQIEHHEFGGASIDTFGEPLTEKTLNACK 64 Query: 381 RNKVCLKGGLATPVGGGVSSLN----MQLRKELDLFASLVNCANVPGLPT-------RHK 527 R L G + P ++ ++LRK L+LF ++ V G + R + Sbjct: 65 RADAILLGAIGGPKWTDPNNRPEQGLLKLRKSLNLFVNIRPTTVVKGASSLSPLKEERVE 124 Query: 528 NVDIVVIRE 554 D+V++RE Sbjct: 125 GTDLVIVRE 133
>RSMB_DROME (Q05856) Small nuclear ribonucleoprotein-associated protein B| (snRNP-B) (Sm protein B) (Sm-B) (SmB) Length = 199 Score = 29.3 bits (64), Expect = 7.9 Identities = 22/53 (41%), Positives = 24/53 (45%), Gaps = 12/53 (22%) Frame = -1 Query: 268 VTRGPM---PSPGM---------SVTGRGVPSPGRGM*VTVRRAPPPWPGRDG 146 V R PM P PGM GRG P P RG ++ R PP PGR G Sbjct: 147 VPRAPMMGAPPPGMIPGGMPSMPGNMGRGAPPPMRGPPPSMIRGAPP-PGRGG 198
>LEU3_PHOLL (Q7N128) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 29.3 bits (64), Expect = 7.9 Identities = 32/133 (24%), Positives = 54/133 (40%), Gaps = 24/133 (18%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAM----HAPVYFETYDVHG-----DMPAVPPAVIESIR 380 + ++PGDGIGP V ++++A+ + + YDV G ++P + Sbjct: 7 IAVLPGDGIGPEVMAQAYKILDAIRKRFNICITTSEYDVGGIAIDRHGCSLPAKTVAGCE 66 Query: 381 RNKVCLKGGLATPVGGGVSSLN-------MQLRKELDLFASLVNCANVPGL----PTRH- 524 + L G + P + + LRK LF++L GL P R+ Sbjct: 67 QADAILFGSVGGPKWEHLPPAEQPERGALLPLRKHFKLFSNLRPARLYAGLEVFCPLRND 126 Query: 525 ---KNVDIVVIRE 554 K DI+ +RE Sbjct: 127 IAAKGFDILCVRE 139
>TTUC_PSEPU (Q51945) Tartrate dehydrogenase/decarboxylase (EC 1.1.1.93) (EC| 4.1.1.73) (TDH) (D-malate dehydrogenase [decarboxylating]) (EC 1.1.1.83) Length = 364 Score = 29.3 bits (64), Expect = 7.9 Identities = 34/130 (26%), Positives = 56/130 (43%), Gaps = 21/130 (16%) Frame = +3 Query: 228 VTLIPGDGIGPLVTGAVEQVMEAM----HAPVYFETYD--------VHGDMPAVPPAVIE 371 + IPGDGIG V +V+EA + F+T++ HG M +P E Sbjct: 7 IAAIPGDGIGLEVLPEGIRVLEAAALKHGLALEFDTFEWASCDYYLQHGKM--MPDDWAE 64 Query: 372 SIRRNKVCLKGGLATP--VGGGVSSLN--MQLRKELDLFASLVNCANVPGLPTRHKN--- 530 +++ G + P V +S ++ R+E D + ++ PG+P N Sbjct: 65 QLKQYDAIYFGAVDWPDKVPDHISLWGSLLKFRREFDQYVNIRPVRLFPGVPCALANRKV 124 Query: 531 --VDIVVIRE 554 +D VV+RE Sbjct: 125 GDIDFVVVRE 134 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.316 0.136 0.527 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 42,571,006 Number of Sequences: 219361 Number of extensions: 945635 Number of successful extensions: 5126 Number of sequences better than 10.0: 219 Number of HSP's better than 10.0 without gapping: 4649 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5007 length of database: 80,573,946 effective HSP length: 105 effective length of database: 57,541,041 effective search space used: 4545742239 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits)
