ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
menu 
| Clone Name | bart09f07 |
|---|---|
| Clone Library Name | barley_pub |
>PBS1_ARATH (Q9FE20) Serine/threonine-protein kinase PBS1 (EC 2.7.11.1)| (AvrPphB susceptible protein 1) Length = 456 Score = 81.3 bits (199), Expect = 1e-15 Identities = 46/105 (43%), Positives = 64/105 (60%), Gaps = 1/105 (0%) Frame = +3 Query: 144 AIVYSVADLQIATDSFSMDNLVGEGTFGRVYXSQFND-GXVLAVKKLDCTVIPFQSSDDF 320 A ++ +L AT +F D +GEG FGRVY + + G V+AVK+LD + Q + +F Sbjct: 71 AHTFAFRELAAATMNFHPDTFLGEGGFGRVYKGRLDSTGQVVAVKQLDRNGL--QGNREF 128 Query: 321 VELVSXISILHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLLH 455 + V +S+LHHPNL L+GYC + LLVY+F GSL D LH Sbjct: 129 LVEVLMLSLLHHPNLVNLIGYCADGDQRLLVYEFMPLGSLEDHLH 173
>BRI1_LYCPE (Q8L899) Systemin receptor SR160 precursor (EC 2.7.11.1)| (Brassinosteroid LRR receptor kinase) Length = 1207 Score = 79.0 bits (193), Expect = 6e-15 Identities = 45/108 (41%), Positives = 62/108 (57%) Frame = +3 Query: 132 KPXKAIVYSVADLQIATDSFSMDNLVGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSS 311 KP + + + ADL AT+ F D+LVG G FG VY +Q DG V+A+KKL + Q Sbjct: 871 KPLRKLTF--ADLLEATNGFHNDSLVGSGGFGDVYKAQLKDGSVVAIKKL--IHVSGQGD 926 Query: 312 DDFVELVSXISILHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLLH 455 +F + I + H NL L+GYC LLVY++ + GSL D+LH Sbjct: 927 REFTAEMETIGKIKHRNLVPLLGYCKVGEERLLVYEYMKYGSLEDVLH 974
>BRI1_LYCES (Q8GUQ5) Brassinosteroid LRR receptor kinase precursor (EC 2.7.11.1)| (tBRI1) (Altered brassinolide sensitivity 1) (Systemin receptor SR160) Length = 1207 Score = 79.0 bits (193), Expect = 6e-15 Identities = 45/108 (41%), Positives = 62/108 (57%) Frame = +3 Query: 132 KPXKAIVYSVADLQIATDSFSMDNLVGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSS 311 KP + + + ADL AT+ F D+LVG G FG VY +Q DG V+A+KKL + Q Sbjct: 871 KPLRKLTF--ADLLEATNGFHNDSLVGSGGFGDVYKAQLKDGSVVAIKKL--IHVSGQGD 926 Query: 312 DDFVELVSXISILHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLLH 455 +F + I + H NL L+GYC LLVY++ + GSL D+LH Sbjct: 927 REFTAEMETIGKIKHRNLVPLLGYCKVGEERLLVYEYMKYGSLEDVLH 974
>BRI1_ARATH (O22476) BRASSINOSTEROID INSENSITIVE 1 precursor (EC 2.7.11.1)| (AtBRI1) (Brassinosteroid LRR receptor kinase) Length = 1196 Score = 75.9 bits (185), Expect = 5e-14 Identities = 43/108 (39%), Positives = 61/108 (56%) Frame = +3 Query: 132 KPXKAIVYSVADLQIATDSFSMDNLVGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSS 311 KP + + + ADL AT+ F D+L+G G FG VY + DG +A+KKL + Q Sbjct: 866 KPLRKLTF--ADLLQATNGFHNDSLIGSGGFGDVYKAILKDGSAVAIKKL--IHVSGQGD 921 Query: 312 DDFVELVSXISILHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLLH 455 +F+ + I + H NL L+GYC LLVY+F + GSL D+LH Sbjct: 922 REFMAEMETIGKIKHRNLVPLLGYCKVGDERLLVYEFMKYGSLEDVLH 969
>BRL1_ARATH (Q9ZWC8) Serine/threonine-protein kinase BRI1-like 1 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 1) Length = 1166 Score = 73.9 bits (180), Expect = 2e-13 Identities = 43/108 (39%), Positives = 61/108 (56%) Frame = +3 Query: 132 KPXKAIVYSVADLQIATDSFSMDNLVGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSS 311 KP + + + A L AT+ FS + +VG G FG VY +Q DG V+A+KKL I Q Sbjct: 842 KPLRKLTF--AHLLEATNGFSAETMVGSGGFGEVYKAQLRDGSVVAIKKL--IRITGQGD 897 Query: 312 DDFVELVSXISILHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLLH 455 +F+ + I + H NL L+GYC LLVY++ + GSL +LH Sbjct: 898 REFMAEMETIGKIKHRNLVPLLGYCKVGEERLLVYEYMKWGSLETVLH 945
>BRL3_ARATH (Q9LJF3) Serine/threonine-protein kinase BRI1-like 3 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 3) Length = 1164 Score = 72.8 bits (177), Expect = 4e-13 Identities = 41/108 (37%), Positives = 62/108 (57%) Frame = +3 Query: 132 KPXKAIVYSVADLQIATDSFSMDNLVGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSS 311 KP + + + A L AT+ FS D+++G G FG VY ++ DG V+A+KKL + Q Sbjct: 841 KPLRKLTF--AHLLEATNGFSADSMIGSGGFGDVYKAKLADGSVVAIKKL--IQVTGQGD 896 Query: 312 DDFVELVSXISILHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLLH 455 +F+ + I + H NL L+GYC LLVY++ + GSL +LH Sbjct: 897 REFMAEMETIGKIKHRNLVPLLGYCKIGEERLLVYEYMKYGSLETVLH 944
>CRI4_MAIZE (O24585) Putative receptor protein kinase CRINKLY4 precursor (EC| 2.7.11.1) Length = 901 Score = 72.0 bits (175), Expect = 7e-13 Identities = 42/111 (37%), Positives = 63/111 (56%) Frame = +3 Query: 132 KPXKAIVYSVADLQIATDSFSMDNLVGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSS 311 K +A +S +L+ AT FS D+ VG+G+F V+ DG V+AVK+ +SS Sbjct: 486 KIRRAQEFSYEELEQATGGFSEDSQVGKGSFSCVFKGILRDGTVVAVKRAIKASDVKKSS 545 Query: 312 DDFVELVSXISILHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLLHLSD 464 +F + +S L+H +L L+GYC + LLVY+F +GSL+ LH D Sbjct: 546 KEFHNELDLLSRLNHAHLLNLLGYCEDGSERLLVYEFMAHGSLYQHLHGKD 596
>RLCK7_ARATH (Q9LQQ8) Probable serine/threonine-protein kinase RLCKVII (EC| 2.7.11.1) Length = 423 Score = 70.9 bits (172), Expect = 2e-12 Identities = 41/107 (38%), Positives = 61/107 (57%), Gaps = 1/107 (0%) Frame = +3 Query: 141 KAIVYSVADLQIATDSFSMDNLVGEGTFGRVYXSQFND-GXVLAVKKLDCTVIPFQSSDD 317 KA ++ +L AT +F D +GEG FG+V+ V+A+K+LD + Q + Sbjct: 87 KAQTFTFQELAEATGNFRSDCFLGEGGFGKVFKGTIEKLDQVVAIKQLDRNGV--QGIRE 144 Query: 318 FVELVSXISILHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLLHL 458 FV V +S+ HPNL +L+G+C E LLVY++ GSL D LH+ Sbjct: 145 FVVEVLTLSLADHPNLVKLIGFCAEGDQRLLVYEYMPQGSLEDHLHV 191
>TMK1_ARATH (P43298) Putative receptor protein kinase TMK1 precursor (EC| 2.7.11.1) Length = 942 Score = 69.7 bits (169), Expect = 3e-12 Identities = 33/98 (33%), Positives = 61/98 (62%) Frame = +3 Query: 147 IVYSVADLQIATDSFSMDNLVGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSSDDFVE 326 ++ S+ L+ T++FS DN++G G FG VY + +DG +AVK+++ VI + +F Sbjct: 574 MLISIQVLRSVTNNFSSDNILGSGGFGVVYKGELHDGTKIAVKRMENGVIAGKGFAEFKS 633 Query: 327 LVSXISILHHPNLNELVGYCMEHGXHLLVYDFHRNGSL 440 ++ ++ + H +L L+GYC++ LLVY++ G+L Sbjct: 634 EIAVLTKVRHRHLVTLLGYCLDGNEKLLVYEYMPQGTL 671
>NAK_ARATH (P43293) Probable serine/threonine-protein kinase NAK (EC 2.7.11.1)| Length = 389 Score = 69.3 bits (168), Expect = 5e-12 Identities = 40/110 (36%), Positives = 65/110 (59%), Gaps = 10/110 (9%) Frame = +3 Query: 153 YSVADLQIATDSFSMDNLVGEGTFGRVYXSQFND----------GXVLAVKKLDCTVIPF 302 +S+++L+ AT +F D++VGEG FG V+ ++ G V+AVK+L+ F Sbjct: 56 FSLSELKSATRNFRPDSVVGEGGFGCVFKGWIDESSLAPSKPGTGIVIAVKRLNQE--GF 113 Query: 303 QSSDDFVELVSXISILHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 Q +++ ++ + L HPNL +L+GYC+E LLVY+F GSL + L Sbjct: 114 QGHREWLAEINYLGQLDHPNLVKLIGYCLEEEHRLLVYEFMTRGSLENHL 163
>BAK1_ARATH (Q94F62) BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1| precursor (EC 2.7.11.1) (BRI1-associated receptor kinase 1) (Somatic embryogenesis receptor-like kinase 3) Length = 615 Score = 67.4 bits (163), Expect = 2e-11 Identities = 40/105 (38%), Positives = 59/105 (56%), Gaps = 5/105 (4%) Frame = +3 Query: 153 YSVADLQIATDSFSMDNLVGEGTFGRVYXSQFNDGXVLAVKKL-----DCTVIPFQSSDD 317 +S+ +LQ+A+D+FS N++G G FG+VY + DG ++AVK+L + FQ+ Sbjct: 277 FSLRELQVASDNFSNKNILGRGGFGKVYKGRLADGTLVAVKRLKEERTQGGELQFQTE-- 334 Query: 318 FVELVSXISILHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 V IS+ H NL L G+CM LLVY + NGS+ L Sbjct: 335 ----VEMISMAVHRNLLRLRGFCMTPTERLLVYPYMANGSVASCL 375
>NORK_PEA (Q8LKZ1) Nodulation receptor kinase precursor (EC 2.7.11.1)| Length = 924 Score = 67.0 bits (162), Expect = 2e-11 Identities = 37/101 (36%), Positives = 58/101 (57%) Frame = +3 Query: 153 YSVADLQIATDSFSMDNLVGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSSDDFVELV 332 +++ +++AT+ + L+GEG FG VY +DG +AVK T Q + +F + Sbjct: 585 FTLEYIELATEKYK--TLIGEGGFGSVYRGTLDDGQEVAVKVRSATST--QGTREFDNEL 640 Query: 333 SXISILHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLLH 455 + +S + H NL L+GYC E+ +LVY F NGSL D L+ Sbjct: 641 NLLSAIQHENLVPLLGYCNEYDQQILVYPFMSNGSLLDRLY 681
>PSKR_ARATH (Q9ZVR7) Putative phytosulfokine receptor precursor (EC 2.7.11.1)| (Phytosulfokine LRR receptor kinase) Length = 1008 Score = 66.6 bits (161), Expect = 3e-11 Identities = 41/102 (40%), Positives = 53/102 (51%), Gaps = 2/102 (1%) Frame = +3 Query: 156 SVADLQIATDSFSMDNLVGEGTFGRVYXSQFNDGXVLAVKKL--DCTVIPFQSSDDFVEL 329 S DL +T+SF N++G G FG VY + DG +A+KKL DC Q +F Sbjct: 723 SYDDLLDSTNSFDQANIIGCGGFGMVYKATLPDGKKVAIKKLSGDCG----QIEREFEAE 778 Query: 330 VSXISILHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLLH 455 V +S HPNL L G+C LL+Y + NGSL LH Sbjct: 779 VETLSRAQHPNLVLLRGFCFYKNDRLLIYSYMENGSLDYWLH 820
>APK1B_ARATH (P46573) Protein kinase APK1B, chloroplast precursor (EC 2.7.11.1)| Length = 412 Score = 66.6 bits (161), Expect = 3e-11 Identities = 39/110 (35%), Positives = 63/110 (57%), Gaps = 10/110 (9%) Frame = +3 Query: 153 YSVADLQIATDSFSMDNLVGEGTFGRVYXSQFND----------GXVLAVKKLDCTVIPF 302 ++ A+L+ AT +F D+++GEG FG V+ ++ G V+AVKKL+ + Sbjct: 57 FTFAELKAATRNFRPDSVLGEGGFGSVFKGWIDEQTLTASKPGTGVVIAVKKLNQD--GW 114 Query: 303 QSSDDFVELVSXISILHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 Q +++ V+ + HPNL +L+GYC+E LLVY+F GSL + L Sbjct: 115 QGHQEWLAEVNYLGQFSHPNLVKLIGYCLEDEHRLLVYEFMPRGSLENHL 164
>CX32_ARATH (P27450) Probable serine/threonine-protein kinase Cx32, chloroplast| precursor (EC 2.7.11.1) Length = 419 Score = 66.2 bits (160), Expect = 4e-11 Identities = 39/111 (35%), Positives = 62/111 (55%), Gaps = 10/111 (9%) Frame = +3 Query: 150 VYSVADLQIATDSFSMDNLVGEGTFGRVYX----------SQFNDGXVLAVKKLDCTVIP 299 VY+ DL+ AT +F D+++G+G FG+VY S+ G ++A+K+L+ + Sbjct: 73 VYNFLDLKTATKNFKPDSMLGQGGFGKVYRGWVDATTLAPSRVGSGMIVAIKRLNSESV- 131 Query: 300 FQSSDDFVELVSXISILHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 Q ++ V+ + +L H NL +L+GYC E LLVY+F GSL L Sbjct: 132 -QGFAEWRSEVNFLGMLSHRNLVKLLGYCREDKELLLVYEFMPKGSLESHL 181
>SRK6_BRAOE (Q09092) Putative serine/threonine-protein kinase receptor| precursor (EC 2.7.11.1) (S-receptor kinase) (SRK) Length = 849 Score = 66.2 bits (160), Expect = 4e-11 Identities = 36/92 (39%), Positives = 57/92 (61%) Frame = +3 Query: 177 ATDSFSMDNLVGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSSDDFVELVSXISILHH 356 AT++FS N +G+G FG VY + DG +AVK+L T + Q +D+F+ V+ I+ L H Sbjct: 524 ATENFSSCNKLGQGGFGIVYKGRLLDGKEIAVKRLSKTSV--QGTDEFMNEVTLIARLQH 581 Query: 357 PNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 NL +++G C+E +L+Y++ N SL L Sbjct: 582 INLVQVLGCCIEGDEKMLIYEYLENLSLDSYL 613
>PSKR_DAUCA (Q8LPB4) Phytosulfokine receptor precursor (EC 2.7.11.1)| (Phytosulfokine LRR receptor kinase) Length = 1021 Score = 66.2 bits (160), Expect = 4e-11 Identities = 38/100 (38%), Positives = 53/100 (53%) Frame = +3 Query: 156 SVADLQIATDSFSMDNLVGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSSDDFVELVS 335 S+ D+ +T SF+ N++G G FG VY + DG +A+K+L Q +F V Sbjct: 732 SLDDILKSTSSFNQANIIGCGGFGLVYKATLPDGTKVAIKRLSGDT--GQMDREFQAEVE 789 Query: 336 XISILHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLLH 455 +S HPNL L+GYC LL+Y + NGSL LH Sbjct: 790 TLSRAQHPNLVHLLGYCNYKNDKLLIYSYMDNGSLDYWLH 829
>BRL2_ARATH (Q9ZPS9) Serine/threonine-protein kinase BRI1-like 2 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 2) (Protein VASCULAR HIGHWAY 1) Length = 1143 Score = 65.1 bits (157), Expect = 9e-11 Identities = 34/93 (36%), Positives = 53/93 (56%) Frame = +3 Query: 177 ATDSFSMDNLVGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSSDDFVELVSXISILHH 356 AT+ FS +++G G FG V+ + DG +A+KKL + Q +F+ + + + H Sbjct: 834 ATNGFSAASMIGHGGFGEVFKATLKDGSSVAIKKL--IRLSCQGDREFMAEMETLGKIKH 891 Query: 357 PNLNELVGYCMEHGXHLLVYDFHRNGSLHDLLH 455 NL L+GYC LLVY+F + GSL ++LH Sbjct: 892 RNLVPLLGYCKIGEERLLVYEFMQYGSLEEVLH 924
>NORK_MEDTR (Q8L4H4) Nodulation receptor kinase precursor (EC 2.7.11.1) (Does| not make infections protein 2) (Symbiosis receptor-like kinase) (MtSYMRK) Length = 925 Score = 64.7 bits (156), Expect = 1e-10 Identities = 37/101 (36%), Positives = 57/101 (56%) Frame = +3 Query: 153 YSVADLQIATDSFSMDNLVGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSSDDFVELV 332 +++ ++ AT+ + L+GEG FG VY +DG +AVK T Q + +F + Sbjct: 586 FTLEYIEQATEQYK--TLIGEGGFGSVYRGTLDDGQEVAVKVRSSTST--QGTREFDNEL 641 Query: 333 SXISILHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLLH 455 + +S + H NL L+GYC E+ +LVY F NGSL D L+ Sbjct: 642 NLLSAIQHENLVPLLGYCNEYDQQILVYPFMSNGSLLDRLY 682
>EXS_ARATH (Q9LYN8) Leucine-rich repeat receptor protein kinase EXS precursor| (EC 2.7.11.1) (Extra sporogenous cells protein) (EXCESS MICROSPOROCYTES1 protein) Length = 1192 Score = 64.3 bits (155), Expect = 1e-10 Identities = 36/94 (38%), Positives = 53/94 (56%) Frame = +3 Query: 159 VADLQIATDSFSMDNLVGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSSDDFVELVSX 338 + D+ ATD FS N++G+G FG VY + +AVKKL + Q + +F+ + Sbjct: 907 LGDIVEATDHFSKKNIIGDGGFGTVYKACLPGEKTVAVKKL--SEAKTQGNREFMAEMET 964 Query: 339 ISILHHPNLNELVGYCMEHGXHLLVYDFHRNGSL 440 + + HPNL L+GYC LLVY++ NGSL Sbjct: 965 LGKVKHPNLVSLLGYCSFSEEKLLVYEYMVNGSL 998
>IRAK1_MOUSE (Q62406) Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1)| (IRAK-1) (IRAK) (Pelle-like protein kinase) (mPLK) Length = 710 Score = 63.5 bits (153), Expect = 3e-10 Identities = 46/149 (30%), Positives = 64/149 (42%), Gaps = 2/149 (1%) Frame = +3 Query: 18 LASPASVGLKPPAKIERNKXXXXXXXXXXKPVAXKSNTKPXKAIVYSVADLQIATDSFSM 197 L P V L PP + PV+ P + ++ T +FS Sbjct: 159 LQVPLPVSLGPPLP---SSAPSSTKSSPESPVSGLQRAHPSP-FCWPFCEISQGTCNFSE 214 Query: 198 DNLVGEGTFGRVYXSQFNDGXVLAVKKL--DCTVIPFQSSDDFVELVSXISILHHPNLNE 371 + +GEG FG VY + + AVK+L + + F+ V +S HPN+ + Sbjct: 215 ELRIGEGGFGCVYRAVMRN-TTYAVKRLKEEADLEWTMVKQSFLTEVEQLSRFRHPNIVD 273 Query: 372 LVGYCMEHGXHLLVYDFHRNGSLHDLLHL 458 GYC E G + LVY F NGSL D LHL Sbjct: 274 FAGYCAESGLYCLVYGFLPNGSLEDQLHL 302
>IRAK1_HUMAN (P51617) Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1)| (IRAK-1) Length = 712 Score = 61.6 bits (148), Expect = 1e-09 Identities = 37/107 (34%), Positives = 56/107 (52%), Gaps = 6/107 (5%) Frame = +3 Query: 153 YSVADLQIATDSFSMDNLVGEGTFGRVYXSQFNDGXVLAVKKL------DCTVIPFQSSD 314 + + ++ T +FS + +GEG FG VY + + V AVK+L + T + Sbjct: 200 WPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRN-TVYAVKRLKENADLEWTAV----KQ 254 Query: 315 DFVELVSXISILHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLLH 455 F+ V +S HPN+ + GYC ++G + LVY F NGSL D LH Sbjct: 255 SFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLH 301
>APK1A_ARATH (Q06548) Protein kinase APK1A, chloroplast precursor (EC 2.7.11.1)| Length = 410 Score = 61.2 bits (147), Expect = 1e-09 Identities = 38/110 (34%), Positives = 62/110 (56%), Gaps = 10/110 (9%) Frame = +3 Query: 153 YSVADLQIATDSFSMDNLVGEGTFGRVYXSQFND----------GXVLAVKKLDCTVIPF 302 +S A+L+ AT +F D+++GEG FG V+ ++ G V+AVKKL+ + Sbjct: 56 FSFAELKSATRNFRPDSVLGEGGFGCVFKGWIDEKSLTASRPGTGLVIAVKKLNQD--GW 113 Query: 303 QSSDDFVELVSXISILHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 Q +++ V+ + H +L +L+GYC+E LLVY+F GSL + L Sbjct: 114 QGHQEWLAEVNYLGQFSHRHLVKLIGYCLEDEHRLLVYEFMPRGSLENHL 163
>RPK1_IPONI (P93194) Receptor-like protein kinase precursor (EC 2.7.11.1)| Length = 1109 Score = 53.9 bits (128), Expect = 2e-07 Identities = 31/93 (33%), Positives = 49/93 (52%) Frame = +3 Query: 177 ATDSFSMDNLVGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSSDDFVELVSXISILHH 356 AT++ + ++G+G G +Y + + V AVKKL T I S V + I + H Sbjct: 812 ATENLNDKYVIGKGAHGTIYKATLSPDKVYAVKKLVFTGIK-NGSVSMVREIETIGKVRH 870 Query: 357 PNLNELVGYCMEHGXHLLVYDFHRNGSLHDLLH 455 NL +L + + L++Y + NGSLHD+LH Sbjct: 871 RNLIKLEEFWLRKEYGLILYTYMENGSLHDILH 903
>SIRK_ARATH (O64483) Senescence-induced receptor-like serine/threonine-protein| kinase precursor (FLG22-induced receptor-like kinase 1) Length = 876 Score = 53.1 bits (126), Expect = 3e-07 Identities = 31/90 (34%), Positives = 50/90 (55%), Gaps = 3/90 (3%) Frame = +3 Query: 192 SMDNLVGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSSDDFVELVSXISIL---HHPN 362 + + ++G+G FG+VY N G +AVK V+ +S+ + E + + +L HH N Sbjct: 575 NFERVIGKGGFGKVYHGVIN-GEQVAVK-----VLSEESAQGYKEFRAEVDLLMRVHHTN 628 Query: 363 LNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 L LVGYC E +L+Y++ N +L D L Sbjct: 629 LTSLVGYCNEINHMVLIYEYMANENLGDYL 658
>KPRO_MAIZE (P17801) Putative receptor protein kinase ZmPK1 precursor (EC| 2.7.11.1) Length = 817 Score = 51.6 bits (122), Expect = 1e-06 Identities = 35/100 (35%), Positives = 51/100 (51%) Frame = +3 Query: 153 YSVADLQIATDSFSMDNLVGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSSDDFVELV 332 YS +L AT F ++ +G G G VY D +AVKKL+ Q + F + Sbjct: 524 YSYRELVKATRKFKVE--LGRGESGTVYKGVLEDDRHVAVKKLENVR---QGKEVFQAEL 578 Query: 333 SXISILHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 S I ++H NL + G+C E LLV ++ NGSL ++L Sbjct: 579 SVIGRINHMNLVRIWGFCSEGSHRLLVSEYVENGSLANIL 618
>RLK5_ARATH (P47735) Receptor-like protein kinase 5 precursor (EC 2.7.11.1)| Length = 999 Score = 50.8 bits (120), Expect = 2e-06 Identities = 33/102 (32%), Positives = 49/102 (48%), Gaps = 11/102 (10%) Frame = +3 Query: 183 DSFSMDNLVGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSSDD-----------FVEL 329 D N++G G+ G+VY + G V+AVKKL+ +V + DD F Sbjct: 681 DCLDEKNVIGFGSSGKVYKVELRGGEVVAVKKLNKSV---KGGDDEYSSDSLNRDVFAAE 737 Query: 330 VSXISILHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLLH 455 V + + H ++ L C LLVY++ NGSL D+LH Sbjct: 738 VETLGTIRHKSIVRLWCCCSSGDCKLLVYEYMPNGSLADVLH 779
>IRAK2_HUMAN (O43187) Interleukin-1 receptor-associated kinase-like 2 (IRAK-2)| Length = 590 Score = 50.1 bits (118), Expect = 3e-06 Identities = 33/105 (31%), Positives = 50/105 (47%), Gaps = 2/105 (1%) Frame = +3 Query: 144 AIVYSVADLQIATDSFSMDNLVGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSS-DDF 320 ++ +S AD+ ATD F+ + + +GTF VY G KKL T S + F Sbjct: 195 SLFWSEADVVQATDDFNQNRKISQGTFADVYRGH-RHGKPFVFKKLRETACSSPGSIERF 253 Query: 321 VELVSXISI-LHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 + I + HPN+ ++G+C H +Y + NGSL D L Sbjct: 254 FQAELQICLRCCHPNVLPVLGFCAARQFHSFIYPYMANGSLQDRL 298
>KPEL_DROME (Q05652) Probable serine/threonine-protein kinase pelle (EC| 2.7.11.1) Length = 501 Score = 48.5 bits (114), Expect = 8e-06 Identities = 33/100 (33%), Positives = 53/100 (53%), Gaps = 7/100 (7%) Frame = +3 Query: 162 ADLQIATDSFSMDNLVGEGTFGRVYXSQFNDGXVLAVK-------KLDCTVIPFQSSDDF 320 A+L+ ATD +S DN +G+G FG VY ++ V A+K +D ++ Q S + Sbjct: 204 AELENATDGWSPDNRLGQGGFGDVYRGKWKQLDV-AIKVMNYRSPNIDQKMVELQQSYNE 262 Query: 321 VELVSXISILHHPNLNELVGYCMEHGXHLLVYDFHRNGSL 440 ++ ++ I H N+ L GY ++ G LVY + GSL Sbjct: 263 LKYLNSI---RHDNILALYGYSIKGGKPCLVYQLMKGGSL 299
>IRAK4_MOUSE (Q8R4K2) Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1)| (IRAK-4) Length = 459 Score = 47.0 bits (110), Expect = 2e-05 Identities = 36/112 (32%), Positives = 54/112 (48%), Gaps = 8/112 (7%) Frame = +3 Query: 153 YSVADLQIATDSFSMD------NLVGEGTFGRVYXSQFNDGXVLAVKKLDCTV--IPFQS 308 +S +L+ T++F N +GEG FG VY N+ ++AVKKL V + Sbjct: 168 FSFHELKSITNNFDEQPASAGGNRMGEGGFGVVYKGCVNN-TIVAVKKLGAMVEISTEEL 226 Query: 309 SDDFVELVSXISILHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLLHLSD 464 F + + ++ H NL EL+G+ + LVY + NGSL D L D Sbjct: 227 KQQFDQEIKVMATCQHENLVELLGFSSDSDNLCLVYAYMPNGSLLDRLSCLD 278
>ITK_MOUSE (Q03526) Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2)| (T-cell-specific kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (Kinase TLK) Length = 625 Score = 47.0 bits (110), Expect = 2e-05 Identities = 26/82 (31%), Positives = 42/82 (51%) Frame = +3 Query: 207 VGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHPNLNELVGYC 386 +G G FG V+ + + +A+K + + S +DF+E + L HP L +L G C Sbjct: 374 IGSGQFGLVHLGYWLNKDKVAIKTIQEGAM---SEEDFIEEAEVMMKLSHPKLVQLYGVC 430 Query: 387 MEHGXHLLVYDFHRNGSLHDLL 452 +E LV++F +G L D L Sbjct: 431 LEQAPICLVFEFMEHGCLSDYL 452
>ITK_HUMAN (Q08881) Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2)| (T-cell-specific kinase) (Tyrosine-protein kinase Lyk) (Kinase EMT) Length = 620 Score = 46.2 bits (108), Expect = 4e-05 Identities = 26/82 (31%), Positives = 42/82 (51%) Frame = +3 Query: 207 VGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHPNLNELVGYC 386 +G G FG V+ + + +A+K + + S +DF+E + L HP L +L G C Sbjct: 369 IGSGQFGLVHLGYWLNKDKVAIKTIREGAM---SEEDFIEEAEVMMKLSHPKLVQLYGVC 425 Query: 387 MEHGXHLLVYDFHRNGSLHDLL 452 +E LV++F +G L D L Sbjct: 426 LEQAPICLVFEFMEHGCLSDYL 447
>TIE2_HUMAN (Q02763) Angiopoietin-1 receptor precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen) Length = 1124 Score = 45.8 bits (107), Expect = 5e-05 Identities = 34/121 (28%), Positives = 57/121 (47%), Gaps = 7/121 (5%) Frame = +3 Query: 120 KSNTKPXKAIVYSVADLQIATDSFSMDNLVGEGTFGRVYXSQFN-DGXVL--AVKKLDCT 290 K+N P +Y V D + +++GEG FG+V ++ DG + A+K++ Sbjct: 808 KNNPDPT---IYPVLDW----NDIKFQDVIGEGNFGQVLKARIKKDGLRMDAAIKRMK-- 858 Query: 291 VIPFQSSDDFVELVSXISIL----HHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLLHL 458 + S DD + + +L HHPN+ L+G C G L ++ +G+L D L Sbjct: 859 --EYASKDDHRDFAGELEVLCKLGHHPNIINLLGACEHRGYLYLAIEYAPHGNLLDFLRK 916 Query: 459 S 461 S Sbjct: 917 S 917
>TIE2_MOUSE (Q02858) Angiopoietin-1 receptor precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen) Length = 1122 Score = 45.8 bits (107), Expect = 5e-05 Identities = 34/121 (28%), Positives = 57/121 (47%), Gaps = 7/121 (5%) Frame = +3 Query: 120 KSNTKPXKAIVYSVADLQIATDSFSMDNLVGEGTFGRVYXSQFN-DGXVL--AVKKLDCT 290 K+N P +Y V D + +++GEG FG+V ++ DG + A+K++ Sbjct: 806 KNNPDPT---IYPVLDW----NDIKFQDVIGEGNFGQVLKARIKKDGLRMDAAIKRMK-- 856 Query: 291 VIPFQSSDDFVELVSXISIL----HHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLLHL 458 + S DD + + +L HHPN+ L+G C G L ++ +G+L D L Sbjct: 857 --EYASKDDHRDFAGELEVLCKLGHHPNIINLLGACEHRGYLYLAIEYAPHGNLLDFLRK 914 Query: 459 S 461 S Sbjct: 915 S 915
>BTKL_DROME (P08630) Tyrosine-protein kinase Btk29A (EC 2.7.10.2) (Dsrc28C)| Length = 786 Score = 45.8 bits (107), Expect = 5e-05 Identities = 27/82 (32%), Positives = 43/82 (52%) Frame = +3 Query: 207 VGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHPNLNELVGYC 386 +G G FG V ++ AVK + + S DDF+E ++ L HPNL +L G C Sbjct: 532 LGSGQFGVVRRGKWRGSIDTAVKMMKEGTM---SEDDFIEEAKVMTKLQHPNLVQLYGVC 588 Query: 387 MEHGXHLLVYDFHRNGSLHDLL 452 +H +V ++ ++GSL + L Sbjct: 589 SKHRPIYIVTEYMKHGSLLNYL 610
>CLV1_ARATH (Q9SYQ8) Receptor protein kinase CLAVATA1 precursor (EC 2.7.11.1)| Length = 980 Score = 45.8 bits (107), Expect = 5e-05 Identities = 25/86 (29%), Positives = 45/86 (52%) Frame = +3 Query: 198 DNLVGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHPNLNELV 377 +N++G+G G VY + +A+K+L +S F + + + H ++ L+ Sbjct: 695 ENIIGKGGAGIVYRGSMPNNVDVAIKRLVGRGTG-RSDHGFTAEIQTLGRIRHRHIVRLL 753 Query: 378 GYCMEHGXHLLVYDFHRNGSLHDLLH 455 GY +LL+Y++ NGSL +LLH Sbjct: 754 GYVANKDTNLLLYEYMPNGSLGELLH 779
>TIE2_BOVIN (Q06807) Angiopoietin-1 receptor precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor TIE-2) (CD202b antigen) Length = 1125 Score = 45.8 bits (107), Expect = 5e-05 Identities = 34/121 (28%), Positives = 57/121 (47%), Gaps = 7/121 (5%) Frame = +3 Query: 120 KSNTKPXKAIVYSVADLQIATDSFSMDNLVGEGTFGRVYXSQFN-DGXVL--AVKKLDCT 290 K+N P +Y V D + +++GEG FG+V ++ DG + A+K++ Sbjct: 809 KNNPDPT---IYPVLDW----NDIKFQDVIGEGNFGQVLKARIKKDGLRMDAAIKRMK-- 859 Query: 291 VIPFQSSDDFVELVSXISIL----HHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLLHL 458 + S DD + + +L HHPN+ L+G C G L ++ +G+L D L Sbjct: 860 --EYASKDDHRDFAGELEVLCKLGHHPNIINLLGACEHRGYLYLAIEYAPHGNLLDFLRK 917 Query: 459 S 461 S Sbjct: 918 S 918
>IRAK3_HUMAN (Q9Y616) Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1)| (IRAK-3) (IL-1 receptor-associated kinase M) (IRAK-M) Length = 596 Score = 45.4 bits (106), Expect = 7e-05 Identities = 31/97 (31%), Positives = 45/97 (46%), Gaps = 6/97 (6%) Frame = +3 Query: 180 TDSFSMDNLVGEGTFGRVYXSQFNDGXVLAVK------KLDCTVIPFQSSDDFVELVSXI 341 T +F D L+GEG VY + + AVK K+ C + F+ + + Sbjct: 162 TRNFHKDFLIGEGEIFEVYRVEIQN-LTYAVKLFKQEKKMQCK----KHWKRFLSELEVL 216 Query: 342 SILHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 + HHPN+ EL Y E L+Y + RNG+L D L Sbjct: 217 LLFHHPNILELAAYFTETEKFCLIYPYMRNGTLFDRL 253
>IPL1_ASHGO (Q755C4) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 367 Score = 45.4 bits (106), Expect = 7e-05 Identities = 28/87 (32%), Positives = 43/87 (49%), Gaps = 2/87 (2%) Frame = +3 Query: 189 FSMDNLVGEGTFGRVY-XSQFNDGXVLAVKKLDCT-VIPFQSSDDFVELVSXISILHHPN 362 F + ++G+G FGRVY G V A+K ++ +I + F V S L HPN Sbjct: 109 FEIGKVLGKGKFGRVYCVRHIESGFVCALKAMEKKDIIQYNIEKQFRREVEIQSSLRHPN 168 Query: 363 LNELVGYCMEHGXHLLVYDFHRNGSLH 443 L +L GY + L+ ++ NG L+ Sbjct: 169 LTQLYGYFHDEKRVYLLMEYLVNGELY 195
>IRAK4_HUMAN (Q9NWZ3) Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1)| (IRAK-4) (NY-REN-64 antigen) Length = 460 Score = 45.1 bits (105), Expect = 9e-05 Identities = 37/112 (33%), Positives = 53/112 (47%), Gaps = 8/112 (7%) Frame = +3 Query: 153 YSVADLQIATDSFSM------DNLVGEGTFGRVYXSQFNDGXVLAVKKLDCTV--IPFQS 308 +S +L+ T++F N +GEG FG VY N+ V AVKKL V + Sbjct: 168 FSFYELKNVTNNFDERPISVGGNKMGEGGFGVVYKGYVNNTTV-AVKKLAAMVDITTEEL 226 Query: 309 SDDFVELVSXISILHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLLHLSD 464 F + + ++ H NL EL+G+ + LVY + NGSL D L D Sbjct: 227 KQQFDQEIKVMAKCQHENLVELLGFSSDGDDLCLVYVYMPNGSLLDRLSCLD 278
>IPL1_YEAST (P38991) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) (Increase-in-ploidy protein 1) Length = 367 Score = 45.1 bits (105), Expect = 9e-05 Identities = 27/97 (27%), Positives = 49/97 (50%), Gaps = 2/97 (2%) Frame = +3 Query: 174 IATDSFSMDNLVGEGTFGRVYXSQFND-GXVLAVKKLDCT-VIPFQSSDDFVELVSXISI 347 ++ D F + +G+G FG+VY + G + A+K ++ +I + F V + Sbjct: 99 LSLDDFELGKKLGKGKFGKVYCVRHRSTGYICALKVMEKEEIIKYNLQKQFRREVEIQTS 158 Query: 348 LHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLLHL 458 L+HPNL + GY + L+ ++ NG ++ LL L Sbjct: 159 LNHPNLTKSYGYFHDEKRVYLLMEYLVNGEMYKLLRL 195
>ABL_DROME (P00522) Tyrosine-protein kinase Abl (EC 2.7.10.2) (Abelson| protein) (D-ash) Length = 1620 Score = 44.3 bits (103), Expect = 2e-04 Identities = 27/95 (28%), Positives = 47/95 (49%), Gaps = 1/95 (1%) Frame = +3 Query: 171 QIATDSFSMDNLVGEGTFGRVYXSQFND-GXVLAVKKLDCTVIPFQSSDDFVELVSXISI 347 +I M + +G G +G VY + + G +AVK L + + DF+E + + Sbjct: 365 EICRTDIMMKHKLGGGQYGEVYEAVWKRYGNTVAVKTLKEDTMALK---DFLEEAAIMKE 421 Query: 348 LHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 + HPNL +L+G C ++ +F +G+L D L Sbjct: 422 MKHPNLVQLIGVCTREPPFYIITEFMSHGNLLDFL 456
>UFO_HUMAN (P30530) Tyrosine-protein kinase receptor UFO precursor (EC| 2.7.10.1) (AXL oncogene) Length = 887 Score = 43.9 bits (102), Expect = 2e-04 Identities = 27/105 (25%), Positives = 46/105 (43%), Gaps = 9/105 (8%) Frame = +3 Query: 165 DLQIATDSFSMDNLVGEGTFGRVYXSQFN-DGXVL--AVKKLDCTVIPFQSSDDFVELVS 335 D+ + ++ +GEG FG V Q N D +L AVK + + +DF+ Sbjct: 521 DVMVDRHKVALGKTLGEGEFGAVMEGQLNQDDSILKVAVKTMKIAICTRSELEDFLSEAV 580 Query: 336 XISILHHPNLNELVGYCMEHGXH------LLVYDFHRNGSLHDLL 452 + HPN+ L+G C + +++ F ++G LH L Sbjct: 581 CMKEFDHPNVMRLIGVCFQGSERESFPAPVVILPFMKHGDLHSFL 625
>M3KL4_HUMAN (Q5TCX8) Mitogen-activated protein kinase kinase kinase (EC| 2.7.11.25) (Mixed lineage kinase 4) Length = 1036 Score = 43.9 bits (102), Expect = 2e-04 Identities = 28/97 (28%), Positives = 49/97 (50%), Gaps = 2/97 (2%) Frame = +3 Query: 168 LQIATDSFSMDNLVGEGTFGRVYXSQFNDGXVLAVK--KLDCTVIPFQSSDDFVELVSXI 341 + +A + + L+G G FG+VY + + G +AVK + D +++ Sbjct: 117 VHVAFERLELKELIGAGGFGQVYRATWQ-GQEVAVKAARQDPEQDAAAAAESVRREARLF 175 Query: 342 SILHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 ++L HPN+ EL G C++ LV +F R G+L+ L Sbjct: 176 AMLRHPNIIELRGVCLQQPHLCLVLEFARGGALNRAL 212
>UFO_MOUSE (Q00993) Tyrosine-protein kinase receptor UFO precursor (EC| 2.7.10.1) (Adhesion-related kinase) Length = 888 Score = 43.9 bits (102), Expect = 2e-04 Identities = 27/105 (25%), Positives = 46/105 (43%), Gaps = 9/105 (8%) Frame = +3 Query: 165 DLQIATDSFSMDNLVGEGTFGRVYXSQFN-DGXVL--AVKKLDCTVIPFQSSDDFVELVS 335 D+ + ++ +GEG FG V Q N D +L AVK + + +DF+ Sbjct: 522 DVMVDRHKVALGKTLGEGEFGAVMEGQLNQDDSILKVAVKTMKIAICTRSELEDFLSEAV 581 Query: 336 XISILHHPNLNELVGYCMEHGXH------LLVYDFHRNGSLHDLL 452 + HPN+ L+G C + +++ F ++G LH L Sbjct: 582 CMKEFDHPNVMRLIGVCFQGSDREGFPEPVVILPFMKHGDLHSFL 626
>TRK1_LYMST (O76997) Putative neurotrophin receptor LTRK 1 precursor (EC| 2.7.10.1) Length = 794 Score = 43.5 bits (101), Expect = 3e-04 Identities = 25/91 (27%), Positives = 43/91 (47%), Gaps = 6/91 (6%) Frame = +3 Query: 204 LVGEGTFGRVYXS------QFNDGXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHPNL 365 ++GEG FGRV+ Q N+ ++AVK L + DF ++ + H N+ Sbjct: 509 VIGEGAFGRVFLGTCAHLIQKNEFAIVAVKTLKGSCSD-SLKRDFEREAEMLATIEHANI 567 Query: 366 NELVGYCMEHGXHLLVYDFHRNGSLHDLLHL 458 G C E +++++F NG L+ L + Sbjct: 568 VTFYGVCTESDQWMMIFEFMENGDLNKYLRM 598
>EGL15_CAEEL (Q10656) Myoblast growth factor receptor egl-15 precursor (EC| 2.7.10.1) (Egg-laying defective protein 15) Length = 1040 Score = 43.5 bits (101), Expect = 3e-04 Identities = 27/98 (27%), Positives = 49/98 (50%), Gaps = 4/98 (4%) Frame = +3 Query: 171 QIATDSFSMDNLVGEGTFGRVYXSQF----NDGXVLAVKKLDCTVIPFQSSDDFVELVSX 338 ++ S+ +++GEG FG V+ + + N+ +AVKKL + + D E+ + Sbjct: 634 EVERSKLSLVHMLGEGAFGEVWKATYKETENNEIAVAVKKLKMSAHEKELIDLVSEMETF 693 Query: 339 ISILHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 I H N+ L+G C G +V + ++G+L D L Sbjct: 694 KVIGEHENVLRLIGCCTGAGPLYVVVELCKHGNLRDFL 731
>TIE1_HUMAN (P35590) Tyrosine-protein kinase receptor Tie-1 precursor (EC| 2.7.10.1) Length = 1138 Score = 43.1 bits (100), Expect = 3e-04 Identities = 28/100 (28%), Positives = 48/100 (48%), Gaps = 7/100 (7%) Frame = +3 Query: 183 DSFSMDNLVGEGTFGRVYXSQFN-DGXVL--AVKKLDCTVIPFQSSDDFVELVSXISIL- 350 + + ++L+GEG FG+V + DG + A+K L + S +D + + +L Sbjct: 837 EDITFEDLIGEGNFGQVIRAMIKKDGLKMNAAIKMLK----EYASENDHRDFAGELEVLC 892 Query: 351 ---HHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLLHLS 461 HHPN+ L+G C G + ++ G+L D L S Sbjct: 893 KLGHHPNIINLLGACKNRGYLYIAIEYAPYGNLLDFLRKS 932
>TNI3K_RAT (Q7TQP6) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 834 Score = 43.1 bits (100), Expect = 3e-04 Identities = 32/118 (27%), Positives = 55/118 (46%), Gaps = 6/118 (5%) Frame = +3 Query: 120 KSNTKPXKAIVYSVADL----QIATDSFSMDNLVGEGTFGRVYXSQFNDGXVLAVKKLDC 287 KS TK ++ A+L + ++G G+FG+VY + + ++A+K+ Sbjct: 435 KSMTKEKADVLLLRAELPSRFHLQLSEIEFHEIIGSGSFGKVYKGRCRN-KIVAIKRYRA 493 Query: 288 TVIPFQSS-DDFVELVSXISILHHPNLNELVGYCMEHGXHL-LVYDFHRNGSLHDLLH 455 +S D F VS + L+HP + + VG C++ +V + GSL LLH Sbjct: 494 NTYCSKSDVDMFCREVSILCQLNHPCVVQFVGACLDDPSQFAIVTQYISGGSLFSLLH 551
>TNI3K_MOUSE (Q5GIG6) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 833 Score = 43.1 bits (100), Expect = 3e-04 Identities = 32/118 (27%), Positives = 55/118 (46%), Gaps = 6/118 (5%) Frame = +3 Query: 120 KSNTKPXKAIVYSVADL----QIATDSFSMDNLVGEGTFGRVYXSQFNDGXVLAVKKLDC 287 KS TK ++ A+L + ++G G+FG+VY + + ++A+K+ Sbjct: 434 KSMTKEKADVLLLRAELPSRFHLQLSEIEFHEIIGSGSFGKVYKGRCRN-KIVAIKRYRA 492 Query: 288 TVIPFQSS-DDFVELVSXISILHHPNLNELVGYCMEHGXHL-LVYDFHRNGSLHDLLH 455 +S D F VS + L+HP + + VG C++ +V + GSL LLH Sbjct: 493 NTYCSKSDVDMFCREVSILCQLNHPCVVQFVGACLDDPSQFAIVTQYISGGSLFSLLH 550
>TIE1_BOVIN (Q06805) Tyrosine-protein kinase receptor Tie-1 precursor (EC| 2.7.10.1) Length = 1136 Score = 42.7 bits (99), Expect = 5e-04 Identities = 28/100 (28%), Positives = 48/100 (48%), Gaps = 7/100 (7%) Frame = +3 Query: 183 DSFSMDNLVGEGTFGRVYXSQFN-DGXVL--AVKKLDCTVIPFQSSDDFVELVSXISIL- 350 + + ++L+GEG FG+V + DG + A+K L + S +D + + +L Sbjct: 835 EDITFEDLIGEGNFGQVIRAMIKKDGLKMNAAIKMLK----EYASENDHRDFAGELEVLC 890 Query: 351 ---HHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLLHLS 461 HHPN+ L+G C G + ++ G+L D L S Sbjct: 891 KLGHHPNIINLLGACENRGYLYIAIEYAPYGNLLDFLRKS 930
>FGFR1_DROME (Q07407) Fibroblast growth factor receptor homolog 1 precursor (EC| 2.7.10.1) (Protein heartless) Length = 729 Score = 42.7 bits (99), Expect = 5e-04 Identities = 26/87 (29%), Positives = 47/87 (54%), Gaps = 4/87 (4%) Frame = +3 Query: 207 VGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSSDDFVELVSXISIL----HHPNLNEL 374 +GEG FGRV ++ N+ ++AVK V + DD LV + ++ H N+ L Sbjct: 422 LGEGAFGRVVMAEVNN-AIVAVK----MVKEGHTDDDIASLVREMEVMKIIGRHINIINL 476 Query: 375 VGYCMEHGXHLLVYDFHRNGSLHDLLH 455 +G C ++G ++ ++ +G+L D L+ Sbjct: 477 LGCCSQNGPLYVIVEYAPHGNLKDFLY 503
>TIE1_MOUSE (Q06806) Tyrosine-protein kinase receptor Tie-1 precursor (EC| 2.7.10.1) Length = 1134 Score = 42.7 bits (99), Expect = 5e-04 Identities = 28/100 (28%), Positives = 48/100 (48%), Gaps = 7/100 (7%) Frame = +3 Query: 183 DSFSMDNLVGEGTFGRVYXSQFN-DGXVL--AVKKLDCTVIPFQSSDDFVELVSXISIL- 350 + + ++L+GEG FG+V + DG + A+K L + S +D + + +L Sbjct: 833 EDITFEDLIGEGNFGQVIRAMIKKDGLKMNAAIKMLK----EYASENDHRDFAGELEVLC 888 Query: 351 ---HHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLLHLS 461 HHPN+ L+G C G + ++ G+L D L S Sbjct: 889 KLGHHPNIINLLGACENRGYLYIAIEYAPYGNLLDFLRKS 928
>CTR1_ARATH (Q05609) Serine/threonine-protein kinase CTR1 (EC 2.7.11.1)| Length = 821 Score = 42.4 bits (98), Expect = 6e-04 Identities = 31/138 (22%), Positives = 61/138 (44%) Frame = +3 Query: 48 PPAKIERNKXXXXXXXXXXKPVAXKSNTKPXKAIVYSVADLQIATDSFSMDNLVGEGTFG 227 PP + R P++ + + + D+ I ++ +G G+FG Sbjct: 504 PPQNMMRASNQIEAAPMNAPPISQPVPNRANRELGLDGDDMDIPWCDLNIKEKIGAGSFG 563 Query: 228 RVYXSQFNDGXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHPNLNELVGYCMEHGXHL 407 V+ ++++ G +AVK L + ++F+ V+ + L HPN+ +G + Sbjct: 564 TVHRAEWH-GSDVAVKILMEQDFHAERVNEFLREVAIMKRLRHPNIVLFMGAVTQPPNLS 622 Query: 408 LVYDFHRNGSLHDLLHLS 461 +V ++ GSL+ LLH S Sbjct: 623 IVTEYLSRGSLYRLLHKS 640
>ABL1_CAEEL (P03949) Tyrosine-protein kinase abl-1 (EC 2.7.10.2)| Length = 1224 Score = 42.4 bits (98), Expect = 6e-04 Identities = 27/91 (29%), Positives = 43/91 (47%), Gaps = 1/91 (1%) Frame = +3 Query: 195 MDNLVGEGTFGRVYXSQFN-DGXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHPNLNE 371 M N +G G +G VY + +AVK L +P +F+ + + LHH NL Sbjct: 313 MHNKLGGGQYGDVYEGYWKRHDCTIAVKALKEDAMPLH---EFLAEAAIMKDLHHKNLVR 369 Query: 372 LVGYCMEHGXHLLVYDFHRNGSLHDLLHLSD 464 L+G C ++ +F NG+L + L +D Sbjct: 370 LLGVCTHEAPFYIITEFMCNGNLLEYLRRTD 400
>TMKL1_ARATH (P33543) Putative kinase-like protein TMKL1 precursor| Length = 674 Score = 42.4 bits (98), Expect = 6e-04 Identities = 33/109 (30%), Positives = 54/109 (49%), Gaps = 2/109 (1%) Frame = +3 Query: 141 KAIVYSVADLQIATDSFSMDNLVGEGT-FGRVYXSQFNDGXVLAVKKLDCTVIPFQSSDD 317 K +V+ + D + V E T +G VY ++ +DG +A++ L +SS Sbjct: 356 KLVVFQGGENLTLDDVLNATGQVMEKTSYGTVYKAKLSDGGNIALRLLREGTCKDRSS-- 413 Query: 318 FVELVSXISILHHPNLNELVGYCM-EHGXHLLVYDFHRNGSLHDLLHLS 461 + ++ + + H NL L + + G LL+YD+ N SLHDLLH S Sbjct: 414 CLPVIRQLGRIRHENLVPLRAFYQGKRGEKLLIYDYLPNISLHDLLHES 462
>SRK3_SPOLA (P42689) Tyrosine-protein kinase SRK3 (EC 2.7.10.2) (Fragment)| Length = 334 Score = 42.0 bits (97), Expect = 8e-04 Identities = 25/94 (26%), Positives = 44/94 (46%) Frame = +3 Query: 171 QIATDSFSMDNLVGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSSDDFVELVSXISIL 350 +I + + +G+G FG V+ +N +AVK L + + DFV+ + + Sbjct: 60 EIDRTTIQLQRKLGQGNFGEVWAGVWNGTTAVAVKTLKPDTMEVK---DFVQEAQVMKKI 116 Query: 351 HHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 HHPNL +L C +V + + GS+ + L Sbjct: 117 HHPNLLQLYAVCTIGEPIYIVTELMKYGSMLEYL 150
>SSK2_YEAST (P53599) MAP kinase kinase kinase SSK2 (EC 2.7.11.25) (Suppressor of| sensor kinase 2) Length = 1579 Score = 42.0 bits (97), Expect = 8e-04 Identities = 31/112 (27%), Positives = 54/112 (48%), Gaps = 5/112 (4%) Frame = +3 Query: 132 KPXKAIVYSVADLQIATDSFSMDNLVGEGTFGRVYXS-QFNDGXVLAVKKLDCTVIPFQS 308 K K +V + + + + N +G GTFGRVY + ++G +LAVK+++ + +S Sbjct: 1247 KGNKYLVSLASSISNVSMRWQKRNFIGGGTFGRVYSAVDLDNGEILAVKEIN--IQDSKS 1304 Query: 309 SDDFVELV----SXISILHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 L+ S + IL+HPN+ G + + ++ GSL LL Sbjct: 1305 MQKIFPLIKEEMSVLEILNHPNIVSYYGVEVHRDKVNIFMEYCEGGSLAALL 1356
>NTRK1_RAT (P35739) High affinity nerve growth factor receptor precursor (EC| 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (p140-TrkA) (Slow nerve growth factor receptor) (Trk-A) Length = 799 Score = 42.0 bits (97), Expect = 8e-04 Identities = 26/88 (29%), Positives = 45/88 (51%), Gaps = 6/88 (6%) Frame = +3 Query: 207 VGEGTFGRVYXSQF------NDGXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHPNLN 368 +GEG FG+V+ ++ D ++AVK L T + DF +++L H ++ Sbjct: 519 LGEGAFGKVFLAECYNLLNDQDKMLVAVKALKET--SENARQDFHREAELLTMLQHQHIV 576 Query: 369 ELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 G C E G L+V+++ R+G L+ L Sbjct: 577 RFFGVCTEGGPLLMVFEYMRHGDLNRFL 604
>M3K10_HUMAN (Q02779) Mitogen-activated protein kinase kinase kinase 10 (EC| 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST) Length = 954 Score = 42.0 bits (97), Expect = 8e-04 Identities = 27/96 (28%), Positives = 47/96 (48%), Gaps = 2/96 (2%) Frame = +3 Query: 171 QIATDSFSMDNLVGEGTFGRVYXSQFNDGXVLAVK--KLDCTVIPFQSSDDFVELVSXIS 344 +I ++ ++G G FG+VY + + G +AVK +LD P +++ + Sbjct: 92 EIPFHELQLEEIIGVGGFGKVYRALWR-GEEVAVKAARLDPEKDPAVTAEQVCQEARLFG 150 Query: 345 ILHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 L HPN+ L G C+ LV ++ R G+L +L Sbjct: 151 ALQHPNIIALRGACLNPPHLCLVMEYARGGALSRVL 186
>M4K2_MOUSE (Q61161) Mitogen-activated protein kinase kinase kinase kinase 2| (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 2) (MEK kinase kinase 2) (MEKKK 2) (Germinal center kinase) (GCK) (Rab8-interacting protein) Length = 821 Score = 41.6 bits (96), Expect = 0.001 Identities = 29/99 (29%), Positives = 44/99 (44%), Gaps = 3/99 (3%) Frame = +3 Query: 168 LQIATDSFSMDNLVGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSSDDFVELVSXISI 347 LQ D F + VG GT+G VY ++ LA K ++ DD L I+I Sbjct: 9 LQDPRDRFELLQRVGAGTYGDVYKARDTVTSELAAVK----IVKLDPGDDISSLQQEITI 64 Query: 348 LH---HPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLLH 455 L HPN+ +G + + + +F GSL ++ H Sbjct: 65 LRECRHPNVVAYIGSYLRNDRLWICMEFCGGGSLQEIYH 103
>RYK_AVIR3 (P33497) Tyrosine-protein kinase transforming protein RYK (EC| 2.7.10.1) Length = 442 Score = 41.6 bits (96), Expect = 0.001 Identities = 27/105 (25%), Positives = 49/105 (46%), Gaps = 9/105 (8%) Frame = +3 Query: 165 DLQIATDSFSMDNLVGEGTFGRVYXSQFNDGX----VLAVKKLDCTVIPFQSSDDFVELV 332 D+ I ++ S+ ++GEG FG V + + +AVK + + ++F+ Sbjct: 37 DVVIDRNALSLGKVLGEGEFGSVMEGRLSQPEGTPQKVAVKTMKLDNFSHREIEEFLSEA 96 Query: 333 SXISILHHPNLNELVGYCMEHGXH-----LLVYDFHRNGSLHDLL 452 + I HPN+ +L+G C+E ++V F + G LH L Sbjct: 97 ACIKDFDHPNVIKLLGVCIELSSQQIPKPMVVLPFMKYGDLHSFL 141
>M4K2_HUMAN (Q12851) Mitogen-activated protein kinase kinase kinase kinase 2| (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 2) (MEK kinase kinase 2) (MEKKK 2) (Germinal center kinase) (GC kinase) (Rab8-interacting protein) (B lymphocyte serine/threonine-pro Length = 819 Score = 41.6 bits (96), Expect = 0.001 Identities = 29/99 (29%), Positives = 44/99 (44%), Gaps = 3/99 (3%) Frame = +3 Query: 168 LQIATDSFSMDNLVGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSSDDFVELVSXISI 347 LQ D F + VG GT+G VY ++ LA K ++ DD L I+I Sbjct: 8 LQDPRDRFELLQRVGAGTYGDVYKARDTVTSELAAVK----IVKLDPGDDISSLQQEITI 63 Query: 348 LH---HPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLLH 455 L HPN+ +G + + + +F GSL ++ H Sbjct: 64 LRECRHPNVVAYIGSYLRNDRLWICMEFCGGGSLQEIYH 102
>TNI3K_HUMAN (Q59H18) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 936 Score = 41.6 bits (96), Expect = 0.001 Identities = 33/118 (27%), Positives = 54/118 (45%), Gaps = 6/118 (5%) Frame = +3 Query: 120 KSNTKPXKAIVYSVADL----QIATDSFSMDNLVGEGTFGRVYXSQFNDGXVLAVKKLDC 287 KS TK I+ A L + ++G G+FG+VY + + ++A+K+ Sbjct: 537 KSMTKEKADILLLRAGLPSHFHLQLSEIEFHEIIGSGSFGKVYKGRCRN-KIVAIKRYRA 595 Query: 288 TVIPFQSS-DDFVELVSXISILHHPNLNELVGYCM-EHGXHLLVYDFHRNGSLHDLLH 455 +S D F VS + L+HP + + VG C+ + +V + GSL LLH Sbjct: 596 NTYCSKSDVDMFCREVSILCQLNHPCVIQFVGACLNDPSQFAIVTQYISGGSLFSLLH 653
>TNI3K_PONPY (Q5RF15) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) Length = 617 Score = 41.6 bits (96), Expect = 0.001 Identities = 33/118 (27%), Positives = 54/118 (45%), Gaps = 6/118 (5%) Frame = +3 Query: 120 KSNTKPXKAIVYSVADL----QIATDSFSMDNLVGEGTFGRVYXSQFNDGXVLAVKKLDC 287 KS TK I+ A L + ++G G+FG+VY + + ++A+K+ Sbjct: 435 KSMTKEKADILLLRAGLPSHFHLQLSEIEFHEIIGSGSFGKVYKGRCRN-KIVAIKRYRA 493 Query: 288 TVIPFQSS-DDFVELVSXISILHHPNLNELVGYCM-EHGXHLLVYDFHRNGSLHDLLH 455 +S D F VS + L+HP + + VG C+ + +V + GSL LLH Sbjct: 494 NTYCSKSDVDMFCREVSILCQLNHPCVIQFVGACLNDPSQFAIVTQYISGGSLFSLLH 551
>ROR1_DROME (Q24488) Tyrosine-protein kinase transmembrane receptor Ror| precursor (EC 2.7.10.1) (dRor) Length = 685 Score = 41.2 bits (95), Expect = 0.001 Identities = 24/86 (27%), Positives = 42/86 (48%), Gaps = 4/86 (4%) Frame = +3 Query: 207 VGEGTFGRVYXSQF----NDGXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHPNLNEL 374 +GEG FG+VY Q +A+K L ++ DF + IS L H N+ + Sbjct: 416 LGEGAFGKVYKGQLLQPNKTTITVAIKALKENA-SVKTQQDFKREIELISDLKHQNIVCI 474 Query: 375 VGYCMEHGXHLLVYDFHRNGSLHDLL 452 +G + + +++++ NG LH+ L Sbjct: 475 LGVVLNKEPYCMLFEYMANGDLHEFL 500
>M3K9_HUMAN (P80192) Mitogen-activated protein kinase kinase kinase 9 (EC| 2.7.11.25) (Mixed lineage kinase 1) Length = 1104 Score = 41.2 bits (95), Expect = 0.001 Identities = 29/97 (29%), Positives = 51/97 (52%), Gaps = 2/97 (2%) Frame = +3 Query: 168 LQIATDSFSMDNLVGEGTFGRVYXSQFNDGXVLAVK--KLDCTVIPFQSSDDFVELVSXI 341 L+I +++ ++G G FG+VY + F G +AVK + D Q+ ++ + Sbjct: 137 LEIDFAELTLEEIIGIGGFGKVYRA-FWIGDEVAVKAARHDPDEDISQTIENVRQEAKLF 195 Query: 342 SILHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 ++L HPN+ L G C++ LV +F R G L+ +L Sbjct: 196 AMLKHPNIIALRGVCLKEPNLCLVMEFARGGPLNRVL 232
>TYRO3_HUMAN (Q06418) Tyrosine-protein kinase receptor TYRO3 precursor (EC| 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase SKY) (Tyrosine-protein kinase DTK) (Protein-tyrosine kinase byk) Length = 890 Score = 40.8 bits (94), Expect = 0.002 Identities = 27/106 (25%), Positives = 50/106 (47%), Gaps = 10/106 (9%) Frame = +3 Query: 165 DLQIATDSFSMDNLVGEGTFGRVYXSQFN--DGXVL--AVKKLDCTVIPFQSSDDFVELV 332 D+ I F++ ++G+G FG V +Q DG + AVK L +I ++F+ Sbjct: 510 DVLIPEQQFTLGRMLGKGEFGSVREAQLKQEDGSFVKVAVKMLKADIIASSDIEEFLREA 569 Query: 333 SXISILHHPNLNELVGYCMEHGXH------LLVYDFHRNGSLHDLL 452 + + HP++ +LVG + +++ F ++G LH L Sbjct: 570 ACMKEFDHPHVAKLVGVSLRSRAKGRLPIPMVILPFMKHGDLHAFL 615
>TYRO3_RAT (P55146) Tyrosine-protein kinase receptor TYRO3 precursor (EC| 2.7.10.1) (Tyrosine-protein kinase SKY) Length = 880 Score = 40.8 bits (94), Expect = 0.002 Identities = 27/106 (25%), Positives = 50/106 (47%), Gaps = 10/106 (9%) Frame = +3 Query: 165 DLQIATDSFSMDNLVGEGTFGRVYXSQFN--DGXVL--AVKKLDCTVIPFQSSDDFVELV 332 D+ I F++ ++G+G FG V +Q DG + AVK L +I ++F+ Sbjct: 500 DVLIPEQQFTLGRMLGKGEFGSVREAQLKQEDGSFVKVAVKMLKADIIASSDIEEFLREA 559 Query: 333 SXISILHHPNLNELVGYCMEHGXH------LLVYDFHRNGSLHDLL 452 + + HP++ +LVG + +++ F ++G LH L Sbjct: 560 ACMKEFDHPHVAKLVGVSLRSRAKGRLPIPMVILPFMKHGDLHAFL 605
>TYRO3_MOUSE (P55144) Tyrosine-protein kinase receptor TYRO3 precursor (EC| 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase DTK) (TK19-2) (Etk2/tyro3) Length = 880 Score = 40.8 bits (94), Expect = 0.002 Identities = 27/106 (25%), Positives = 50/106 (47%), Gaps = 10/106 (9%) Frame = +3 Query: 165 DLQIATDSFSMDNLVGEGTFGRVYXSQFN--DGXVL--AVKKLDCTVIPFQSSDDFVELV 332 D+ I F++ ++G+G FG V +Q DG + AVK L +I ++F+ Sbjct: 500 DVLIPEQQFTLGRMLGKGEFGSVREAQLKQEDGSFVKVAVKMLKADIIASSDIEEFLREA 559 Query: 333 SXISILHHPNLNELVGYCMEHGXH------LLVYDFHRNGSLHDLL 452 + + HP++ +LVG + +++ F ++G LH L Sbjct: 560 ACMKEFDHPHVAKLVGVSLRSRAKGRLPIPMVILPFMKHGDLHAFL 605
>ZYG1_CAEBR (Q621J7) Probable serine/threonine-protein kinase zyg-1 (EC| 2.7.11.1) (Zygote defective protein 1) Length = 709 Score = 40.8 bits (94), Expect = 0.002 Identities = 26/87 (29%), Positives = 40/87 (45%) Frame = +3 Query: 186 SFSMDNLVGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHPNL 365 SF +G+G FG VY +Q +G +A+KK+ S E + + +L H N+ Sbjct: 12 SFQNLQQIGQGGFGVVYSAQRENGEKVAIKKIGNAA----SQTRIKEEIKTMKLLRHRNI 67 Query: 366 NELVGYCMEHGXHLLVYDFHRNGSLHD 446 + E+G LV + GSL D Sbjct: 68 VQFYETFFENGETYLVMELCEGGSLMD 94
>SRK2_SPOLA (P42688) Tyrosine-protein kinase SRK2 (EC 2.7.10.2) (Fragment)| Length = 362 Score = 40.4 bits (93), Expect = 0.002 Identities = 26/94 (27%), Positives = 42/94 (44%) Frame = +3 Query: 171 QIATDSFSMDNLVGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSSDDFVELVSXISIL 350 +I+ DS ++ +G G FG VY +N+ +AVK L + F+ + L Sbjct: 89 EISRDSITLIRKLGAGQFGEVYQGLWNNSTPVAVKTLKAGTM---QPAAFLAEAQIMKKL 145 Query: 351 HHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 HP L +L C + ++ + GSL D L Sbjct: 146 RHPKLIQLYAVCTQGEPVYIITELMSKGSLLDYL 179
>M4K3_MOUSE (Q99JP0) Mitogen-activated protein kinase kinase kinase kinase 3| (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 3) (MEK kinase kinase 3) (MEKKK 3) (Germinal center kinase-related protein kinase) (GLK) (Fragments) Length = 681 Score = 40.4 bits (93), Expect = 0.002 Identities = 26/97 (26%), Positives = 46/97 (47%), Gaps = 4/97 (4%) Frame = +3 Query: 183 DSFSMDNLVGEGTFGRVYXSQ-FNDGXVLAVKKLDCTVIPFQSSDDFVELVSXISILH-- 353 + F + +G GT+G VY ++ N G + A+K VI + +DF + I ++ Sbjct: 14 EDFELIQRIGSGTYGDVYKARNVNTGELAAIK-----VIKLEPGEDFAVVQQEIIMMKDC 68 Query: 354 -HPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLLHLS 461 HPN+ G + + +F GSL D+ H++ Sbjct: 69 KHPNIVAYFGSYLRRDKLWICMEFCGGGSLQDIYHVT 105
>TXK_MOUSE (P42682) Tyrosine-protein kinase TXK (EC 2.7.10.2) (PTK-RL-18)| (Resting lymphocyte kinase) Length = 527 Score = 40.4 bits (93), Expect = 0.002 Identities = 24/82 (29%), Positives = 41/82 (50%) Frame = +3 Query: 207 VGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHPNLNELVGYC 386 +G G FG V+ ++ +A+K ++ + S +DF+E + L H L +L G C Sbjct: 277 IGSGQFGVVHLGEWRAHIPVAIKAINEGSM---SEEDFIEEAKVMMKLSHSRLVQLYGVC 333 Query: 387 MEHGXHLLVYDFHRNGSLHDLL 452 ++ +V +F NG L D L Sbjct: 334 IQQKPLYIVTEFMENGCLLDYL 355
>M4K3_HUMAN (Q8IVH8) Mitogen-activated protein kinase kinase kinase kinase 3| (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 3) (MEK kinase kinase 3) (MEKKK 3) (Germinal center kinase-related protein kinase) (GLK) Length = 894 Score = 40.4 bits (93), Expect = 0.002 Identities = 26/97 (26%), Positives = 46/97 (47%), Gaps = 4/97 (4%) Frame = +3 Query: 183 DSFSMDNLVGEGTFGRVYXSQ-FNDGXVLAVKKLDCTVIPFQSSDDFVELVSXISILH-- 353 + F + +G GT+G VY ++ N G + A+K VI + +DF + I ++ Sbjct: 14 EDFELIQRIGSGTYGDVYKARNVNTGELAAIK-----VIKLEPGEDFAVVQQEIIMMKDC 68 Query: 354 -HPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLLHLS 461 HPN+ G + + +F GSL D+ H++ Sbjct: 69 KHPNIVAYFGSYLRRDKLWICMEFCGGGSLQDIYHVT 105
>CDC2H_THEPA (Q27032) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 298 Score = 40.0 bits (92), Expect = 0.003 Identities = 19/53 (35%), Positives = 29/53 (54%) Frame = +3 Query: 207 VGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHPNL 365 +GEGT+G VY +Q N G + A+KK+ + +S + LHHPN+ Sbjct: 10 IGEGTYGVVYKAQNNHGEICALKKIRVEEEDEGIPSTAIREISLLKELHHPNI 62
>CDC2H_THEAN (Q26671) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 298 Score = 40.0 bits (92), Expect = 0.003 Identities = 19/53 (35%), Positives = 29/53 (54%) Frame = +3 Query: 207 VGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHPNL 365 +GEGT+G VY +Q N G + A+KK+ + +S + LHHPN+ Sbjct: 10 IGEGTYGVVYKAQNNHGEICALKKIRVEEEDEGIPSTAIREISLLKELHHPNI 62
>TXK_HUMAN (P42681) Tyrosine-protein kinase TXK (EC 2.7.10.2)| Length = 527 Score = 40.0 bits (92), Expect = 0.003 Identities = 29/115 (25%), Positives = 51/115 (44%) Frame = +3 Query: 108 PVAXKSNTKPXKAIVYSVADLQIATDSFSMDNLVGEGTFGRVYXSQFNDGXVLAVKKLDC 287 PV + P A +S +I + +G G FG V+ ++ +A+K ++ Sbjct: 245 PVGLMGSCLPATA-GFSYEKWEIDPSELAFIKEIGSGQFGVVHLGEWRSHIQVAIKAINE 303 Query: 288 TVIPFQSSDDFVELVSXISILHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 + S +DF+E + L H L +L G C++ +V +F NG L + L Sbjct: 304 GSM---SEEDFIEEAKVMMKLSHSKLVQLYGVCIQRKPLYIVTEFMENGCLLNYL 355
>YR831_MIMIV (Q7T6Y2) Putative serine/threonine-protein kinase/receptor R831| precursor (EC 2.7.11.1) Length = 1624 Score = 39.7 bits (91), Expect = 0.004 Identities = 27/96 (28%), Positives = 43/96 (44%) Frame = +3 Query: 165 DLQIATDSFSMDNLVGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSSDDFVELVSXIS 344 D +I + +G G +G VY S + G +AVK + + F E V ++ Sbjct: 778 DWEIDFSELEIGETLGTGGYGEVYKSIWK-GTEVAVKLISSKHVSKDMERSFFEEVKIMT 836 Query: 345 ILHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 L HPN+ + + +V +F GSL+DLL Sbjct: 837 SLRHPNVVLFMAASTKSPNMCIVMEFMSLGSLYDLL 872 Score = 38.5 bits (88), Expect = 0.009 Identities = 25/94 (26%), Positives = 47/94 (50%) Frame = +3 Query: 183 DSFSMDNLVGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHPN 362 D S+ +G G++G V+ ++ G +AVKK + +F ++ +S L H N Sbjct: 1362 DEISIGKQIGLGSYGIVFNGKWK-GVDVAVKKFVKQKLSETQLLEFRAEMAFLSELKHSN 1420 Query: 363 LNELVGYCMEHGXHLLVYDFHRNGSLHDLLHLSD 464 + +G C++ +V ++ R G+L D+L D Sbjct: 1421 IVTFIGACIKKPNICIVTEYMRMGNLRDVLKNPD 1454
>M4K4_MOUSE (P97820) Mitogen-activated protein kinase kinase kinase kinase 4| (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase) Length = 1233 Score = 39.3 bits (90), Expect = 0.005 Identities = 34/121 (28%), Positives = 57/121 (47%), Gaps = 11/121 (9%) Frame = +3 Query: 123 SNTKPXKAIV-YSVADLQIATDSFSMDNLVGEGTFGRVYXSQFNDGXVLAVKKLDCTVIP 299 +N P K++V ++ L+ F + +VG GT+G+VY + A+K +D T Sbjct: 2 ANDSPAKSLVDIDLSSLRDPAGIFELVEVVGNGTYGQVYKGRHVKTVTAAIKVMDVT--- 58 Query: 300 FQSSDDFVELVSXISIL----HHPNLNELVGYCME-----HGXHL-LVYDFHRNGSLHDL 449 D+ E+ I++L HH N+ G ++ H L LV +F GS+ DL Sbjct: 59 ---EDEEEEITLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDL 115 Query: 450 L 452 + Sbjct: 116 V 116
>SEA_AVIET (P23049) Tyrosine-protein kinase transforming protein SEA (EC| 2.7.10.2) Length = 370 Score = 39.3 bits (90), Expect = 0.005 Identities = 25/92 (27%), Positives = 43/92 (46%), Gaps = 5/92 (5%) Frame = +3 Query: 204 LVGEGTFGRVYXSQFNDGXV----LAVKKLDCTVIPFQSSDDFVELVSXISILHHPNLNE 371 ++G G FG VY + D + AVK L + + ++F+ + HHP + Sbjct: 65 VIGRGHFGSVYHGTYMDPLLGNLHCAVKSLH-RITYLEEVEEFLREGILMKGFHHPQVLS 123 Query: 372 LVGYCM-EHGXHLLVYDFHRNGSLHDLLHLSD 464 L+G C+ HG L+V + R+G L + + Sbjct: 124 LLGVCLPRHGLPLVVLPYMRHGDLRHFVRAQE 155
>SRK4_SPOLA (P42690) Tyrosine-protein kinase isoform SRK4 (EC 2.7.10.2)| Length = 506 Score = 39.3 bits (90), Expect = 0.005 Identities = 25/82 (30%), Positives = 41/82 (50%) Frame = +3 Query: 207 VGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHPNLNELVGYC 386 +G G FG V+ +N +AVK L + S ++F+E S + L HP L +L C Sbjct: 246 LGAGQFGEVWEGLWNGTTSVAVKTLKPGTM---SIEEFLEEASIMKQLRHPKLIQLYAVC 302 Query: 387 MEHGXHLLVYDFHRNGSLHDLL 452 + +V + ++GSL + L Sbjct: 303 TKEEPIYIVTELMKHGSLLEYL 324
>ROR1_MOUSE (Q9Z139) Tyrosine-protein kinase transmembrane receptor ROR1| precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1) (mROR1) Length = 937 Score = 39.3 bits (90), Expect = 0.005 Identities = 24/87 (27%), Positives = 44/87 (50%), Gaps = 5/87 (5%) Frame = +3 Query: 207 VGEGTFGRVYXSQF-----NDGXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHPNLNE 371 +GE TFG++Y + ++A+K L P Q +F + S ++ LHHPN+ Sbjct: 479 LGECTFGKIYKGHLYLPGMDHAQLVAIKTLKDYNNP-QQWTEFQQEASLMAELHHPNIVC 537 Query: 372 LVGYCMEHGXHLLVYDFHRNGSLHDLL 452 L+G + +++++ G LH+ L Sbjct: 538 LLGAVTQEQPVCMLFEYMNQGDLHEFL 564
>FLK_RAT (P09760) Tyrosine-protein kinase FLK (EC 2.7.10.2) (Fragment)| Length = 323 Score = 38.9 bits (89), Expect = 0.007 Identities = 20/70 (28%), Positives = 34/70 (48%) Frame = +3 Query: 183 DSFSMDNLVGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHPN 362 + S+ L+G+G FG VY D +AVK +P + F++ + HPN Sbjct: 62 EDVSLGELLGKGNFGEVYKGTLKDKTPVAVKTCK-EDLPQELKIKFLQEAKILKQYDHPN 120 Query: 363 LNELVGYCME 392 + +L+G C + Sbjct: 121 IVKLIGVCTQ 130
>MATK_MOUSE (P41242) Megakaryocyte-associated tyrosine-protein kinase (EC| 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK) Length = 505 Score = 38.9 bits (89), Expect = 0.007 Identities = 21/69 (30%), Positives = 39/69 (56%) Frame = +3 Query: 207 VGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHPNLNELVGYC 386 +GEG FG V ++ G +AVK + C V ++ F++ + ++ L H NL L+G Sbjct: 239 IGEGEFGAVLQGEYL-GQKVAVKNIKCDV----TAQAFLDETAVMTKLQHRNLVRLLGVI 293 Query: 387 MEHGXHLLV 413 + HG ++++ Sbjct: 294 LHHGLYIVM 302
>FRK_HUMAN (P42685) Tyrosine-protein kinase FRK (EC 2.7.10.2) (Nuclear| tyrosine protein kinase RAK) Length = 505 Score = 38.9 bits (89), Expect = 0.007 Identities = 26/99 (26%), Positives = 45/99 (45%) Frame = +3 Query: 156 SVADLQIATDSFSMDNLVGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSSDDFVELVS 335 +V +I +S + +G G FG V+ +N+ +AVK L + +DF+ Sbjct: 223 TVDQWEIDRNSIQLLKRLGSGQFGEVWEGLWNNTTPVAVKTLKPGSM---DPNDFLREAQ 279 Query: 336 XISILHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 + L HP L +L C ++ + R+GSL + L Sbjct: 280 IMKNLRHPKLIQLYAVCTLEDPIYIITELMRHGSLQEYL 318
>MYO3B_HUMAN (Q8WXR4) Myosin IIIB (EC 2.7.11.1)| Length = 1341 Score = 38.9 bits (89), Expect = 0.007 Identities = 31/99 (31%), Positives = 51/99 (51%), Gaps = 8/99 (8%) Frame = +3 Query: 180 TDSFSMDNLVGEGTFGRVY-XSQFNDGXVLAVKKLDCTVIPFQSSDDFVELVSXI--SIL 350 TD++ + +G+GT+G+VY + DG + AVK LD P D+ +E I + Sbjct: 24 TDTWEIIETIGKGTYGKVYKVTNKRDGSLAAVKILD----PVSDMDEEIEAEYNILQFLP 79 Query: 351 HHPNLNELVG--YCMEH---GXHLLVYDFHRNGSLHDLL 452 +HPN+ + G Y +H G LV + GS+ +L+ Sbjct: 80 NHPNVVKFYGMFYKADHCVGGQLWLVLELCNGGSVTELV 118
>MATK_RAT (P41243) Megakaryocyte-associated tyrosine-protein kinase (EC| 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase BATK) Length = 467 Score = 38.9 bits (89), Expect = 0.007 Identities = 21/69 (30%), Positives = 39/69 (56%) Frame = +3 Query: 207 VGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHPNLNELVGYC 386 +GEG FG V ++ G +AVK + C V ++ F++ + ++ L H NL L+G Sbjct: 200 IGEGEFGAVLQGEYL-GQKVAVKNIKCDV----TAQAFLDETAVMTKLQHRNLVRLLGVI 254 Query: 387 MEHGXHLLV 413 + HG ++++ Sbjct: 255 LHHGLYIVM 263
>M3K7_DROME (Q9V3Q6) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (TGF-beta-activated kinase 1) (dTAK1) Length = 678 Score = 38.9 bits (89), Expect = 0.007 Identities = 33/103 (32%), Positives = 47/103 (45%), Gaps = 3/103 (2%) Frame = +3 Query: 156 SVADLQIATDSFSMDNL---VGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSSDDFVE 326 S+ LQ A FS L VG G++G V + + D V AVK+ + D + Sbjct: 5 SLDALQAAYVDFSEITLREKVGHGSYGVVCKAVWRDKLV-AVKEFFASA----EQKDIEK 59 Query: 327 LVSXISILHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLLH 455 V +S + HPN+ L G L+ +F GSLH+ LH Sbjct: 60 EVKQLSRVKHPNIIALHGISSYQQATYLIMEFAEGGSLHNFLH 102
>STK_HYDAT (P17713) Tyrosine-protein kinase STK (EC 2.7.10.2) (P57-STK)| Length = 509 Score = 38.5 bits (88), Expect = 0.009 Identities = 25/94 (26%), Positives = 44/94 (46%) Frame = +3 Query: 171 QIATDSFSMDNLVGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSSDDFVELVSXISIL 350 +I +S ++ +G G FG V+ +N+ +AVK L + S F++ + L Sbjct: 234 EIPRESLRLNRKLGAGQFGEVWAGVWNNTTQVAVKTLKPGTM---SPASFLDEAGVMKKL 290 Query: 351 HHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 H +L +L C + +V ++ GSL D L Sbjct: 291 RHKHLVQLYAICSDREPIYIVTEYMSGGSLLDYL 324
>M4K4_HUMAN (O95819) Mitogen-activated protein kinase kinase kinase kinase 4| (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase) Length = 1239 Score = 38.5 bits (88), Expect = 0.009 Identities = 35/122 (28%), Positives = 59/122 (48%), Gaps = 12/122 (9%) Frame = +3 Query: 123 SNTKPXKAIV-YSVADLQIATDSFSMDNLVGEGTFGRVYXSQ-FNDGXVLAVKKLDCTVI 296 +N P K++V ++ L+ F + +VG GT+G+VY + G + A+K +D T Sbjct: 2 ANDSPAKSLVDIDLSSLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVT-- 59 Query: 297 PFQSSDDFVELVSXISIL----HHPNLNELVGYCME-----HGXHL-LVYDFHRNGSLHD 446 D+ E+ I++L HH N+ G ++ H L LV +F GS+ D Sbjct: 60 ----EDEEEEIKLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITD 115 Query: 447 LL 452 L+ Sbjct: 116 LV 117
>FPS_DROME (P18106) Tyrosine-protein kinase Fps85D (EC 2.7.10.2) (dFer)| Length = 1325 Score = 38.5 bits (88), Expect = 0.009 Identities = 20/90 (22%), Positives = 41/90 (45%) Frame = +3 Query: 171 QIATDSFSMDNLVGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSSDDFVELVSXISIL 350 +++ D + +G G FG VY ++ + K +P + F++ + Sbjct: 1057 ELSNDDVVLLERIGRGNFGDVYKAKLKSTKLDVAVKTCRMTLPDEQKRKFLQEGRILKQY 1116 Query: 351 HHPNLNELVGYCMEHGXHLLVYDFHRNGSL 440 HPN+ +L+G C++ ++V + GSL Sbjct: 1117 DHPNIVKLIGICVQKQPIMIVMELVLGGSL 1146
>RON_MOUSE (Q62190) Macrophage-stimulating protein receptor precursor (EC| 2.7.10.1) (MSP receptor) (p185-Ron) (Stem cell-derived tyrosine kinase) (CDw136 antigen) [Contains: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating prote Length = 1378 Score = 38.5 bits (88), Expect = 0.009 Identities = 25/86 (29%), Positives = 42/86 (48%), Gaps = 5/86 (5%) Frame = +3 Query: 198 DNLVGEGTFGRVYXSQFNDGXV----LAVKKLDCTVIPFQSSDDFVELVSXISILHHPNL 365 D ++G+G FG VY ++ DG A+K L + Q + F+ + LHHPN+ Sbjct: 1062 DQVIGKGHFGVVYHGEYTDGAQNQTHCAIKSLS-RITEVQEVEAFLREGLLMRGLHHPNI 1120 Query: 366 NELVGYCM-EHGXHLLVYDFHRNGSL 440 L+G + G ++ + R+G L Sbjct: 1121 LALIGIMLPPEGLPRVLLPYMRHGDL 1146
>FIN1_SCHPO (O13839) G2-specific protein kinase fin1 (EC 2.7.11.1)| Length = 722 Score = 38.5 bits (88), Expect = 0.009 Identities = 23/71 (32%), Positives = 36/71 (50%), Gaps = 1/71 (1%) Frame = +3 Query: 183 DSFSMDNLVGEGTFGRVYXSQ-FNDGXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHP 359 + + + +G G+FGR+Y Q DG +LA K++ I Q + V+ + L HP Sbjct: 2 EKYKILECIGHGSFGRIYKVQRLKDGALLAQKEIHFGNITRQEKQYIADEVNILRNLKHP 61 Query: 360 NLNELVGYCME 392 N+ V YC E Sbjct: 62 NI---VQYCGE 69
>JAK1_MOUSE (P52332) Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1)| (JAK-1) Length = 1153 Score = 38.1 bits (87), Expect = 0.011 Identities = 30/92 (32%), Positives = 45/92 (48%), Gaps = 10/92 (10%) Frame = +3 Query: 207 VGEGTFGRVYXSQF-----NDGXVLAVKKLDCTVIPFQSSDDFVELVSXISIL---HHPN 362 +GEG FG+V ++ N G +AVK L P + +L I IL +H N Sbjct: 880 LGEGHFGKVELCRYDPEGDNTGEQVAVKSLK----PESGGNHIADLKKEIEILRNLYHEN 935 Query: 363 LNELVGYCMEHGXH--LLVYDFHRNGSLHDLL 452 + + G CME G + L+ +F +GSL + L Sbjct: 936 IVKYKGICMEDGGNGIKLIMEFLPSGSLKEYL 967
>EPHB3_BRARE (O13147) Ephrin type-B receptor 3 (EC 2.7.10.1) (Tyrosine-protein| kinase receptor ZEK3) (EPH-like kinase 3) (Fragment) Length = 500 Score = 38.1 bits (87), Expect = 0.011 Identities = 27/102 (26%), Positives = 42/102 (41%), Gaps = 4/102 (3%) Frame = +3 Query: 171 QIATDSFSMDNLVGEGTFGRVYXSQFNDG----XVLAVKKLDCTVIPFQSSDDFVELVSX 338 +I ++ ++G G FG V + +A+K L Q D F+ S Sbjct: 181 EIDISCVKIEEVIGAGEFGEVCRGRLKQAGRKETTVAIKTLKAGYTEHQRRD-FLSEASI 239 Query: 339 ISILHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLLHLSD 464 + HPN+ L G L+V +F NG+L L L+D Sbjct: 240 MGQFDHPNVIHLEGVLTRSCPVLIVTEFMENGALDSFLRLND 281
>IPL1_DEBHA (Q6BVA0) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 412 Score = 38.1 bits (87), Expect = 0.011 Identities = 22/96 (22%), Positives = 44/96 (45%), Gaps = 2/96 (2%) Frame = +3 Query: 162 ADLQIATDSFSMDNLVGEGTFGRVYXSQFNDGXVLAVKKLDC--TVIPFQSSDDFVELVS 335 A + D F + ++G+G G+VY + +A K+ +I + +F + Sbjct: 139 ASRHMTLDDFEIGKVLGKGKLGKVYCVKHKTSGYIAALKVMAKKDLIDLKLEKNFRREIE 198 Query: 336 XISILHHPNLNELVGYCMEHGXHLLVYDFHRNGSLH 443 S L HP ++ L G+ +H L+ ++ +G L+ Sbjct: 199 IQSNLIHPKISRLYGFFYDHKNVYLILEYSIHGELY 234
>NTRK1_HUMAN (P04629) High affinity nerve growth factor receptor precursor (EC| 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1 transforming tyrosine kinase protein) (p140-TrkA) (Trk-A) Length = 796 Score = 38.1 bits (87), Expect = 0.011 Identities = 24/88 (27%), Positives = 44/88 (50%), Gaps = 6/88 (6%) Frame = +3 Query: 207 VGEGTFGRVYXSQFN------DGXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHPNLN 368 +GEG FG+V+ ++ + D ++AVK L + DF +++L H ++ Sbjct: 516 LGEGAFGKVFLAECHNLLPEQDKMLVAVKALK--EASESARQDFQREAELLTMLQHQHIV 573 Query: 369 ELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 G C E L+V+++ R+G L+ L Sbjct: 574 RFFGVCTEGRPLLMVFEYMRHGDLNRFL 601
>LYN_MOUSE (P25911) Tyrosine-protein kinase Lyn (EC 2.7.10.2)| Length = 511 Score = 38.1 bits (87), Expect = 0.011 Identities = 25/94 (26%), Positives = 42/94 (44%) Frame = +3 Query: 171 QIATDSFSMDNLVGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSSDDFVELVSXISIL 350 +I +S + +G G FG V+ +N+ +AVK L + Q+ F+E + + L Sbjct: 240 EIPRESIKLVKKLGAGQFGEVWMGYYNNSTKVAVKTLKPGTMSVQA---FLEEANLMKTL 296 Query: 351 HHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 H L L + ++ +F GSL D L Sbjct: 297 QHDKLVRLYAVVTKEEPIYIITEFMAKGSLLDFL 330
>SRK1_SPOLA (P42686) Tyrosine-protein kinase isoform SRK1 (EC 2.7.10.2)| Length = 505 Score = 37.7 bits (86), Expect = 0.015 Identities = 25/86 (29%), Positives = 41/86 (47%) Frame = +3 Query: 207 VGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHPNLNELVGYC 386 +G G FG V+ +N +AVK L + S ++F++ S + L HP L +L C Sbjct: 246 LGAGQFGEVWEGLWNGTTSVAVKTLKPGTM---SVEEFLQEASIMKRLRHPKLIQLYAVC 302 Query: 387 MEHGXHLLVYDFHRNGSLHDLLHLSD 464 + +V + + GSL + L D Sbjct: 303 TKEEPIYIVTELMKYGSLLEYLRGED 328
>TESK1_MOUSE (O70146) Dual specificity testis-specific protein kinase 1 (EC| 2.7.12.1) (Testicular protein kinase 1) Length = 627 Score = 37.7 bits (86), Expect = 0.015 Identities = 24/90 (26%), Positives = 40/90 (44%) Frame = +3 Query: 183 DSFSMDNLVGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHPN 362 D F +G G F VY + + V K++ +P S+ E V ++ L HPN Sbjct: 50 DDFDCAEKIGAGFFSEVYKVRHRQSGQVMVLKMN--KLPSNRSNTLRE-VQLMNRLRHPN 106 Query: 363 LNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 + +G C+ G + ++ G+L LL Sbjct: 107 ILRFMGVCVHQGQLHALTEYMNGGTLEQLL 136
>CDC2_ORYLU (Q9DG98) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 37.7 bits (86), Expect = 0.015 Identities = 23/73 (31%), Positives = 37/73 (50%), Gaps = 1/73 (1%) Frame = +3 Query: 207 VGEGTFGRVYXSQF-NDGXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHPNLNELVGY 383 +GEGT+G VY + + G V+A+KK+ V VS + L HPN+ L+ Sbjct: 10 IGEGTYGVVYKGRHKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQELKHPNVVRLLDV 69 Query: 384 CMEHGXHLLVYDF 422 M+ L+++F Sbjct: 70 LMQESRLYLIFEF 82
>CDC2_ORYLA (Q9DGD3) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 37.7 bits (86), Expect = 0.015 Identities = 23/73 (31%), Positives = 37/73 (50%), Gaps = 1/73 (1%) Frame = +3 Query: 207 VGEGTFGRVYXSQF-NDGXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHPNLNELVGY 383 +GEGT+G VY + + G V+A+KK+ V VS + L HPN+ L+ Sbjct: 10 IGEGTYGVVYKGRHKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQELKHPNVVRLLDV 69 Query: 384 CMEHGXHLLVYDF 422 M+ L+++F Sbjct: 70 LMQESRLYLIFEF 82
>CDC2_ORYJA (Q9DGA2) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 37.7 bits (86), Expect = 0.015 Identities = 23/73 (31%), Positives = 37/73 (50%), Gaps = 1/73 (1%) Frame = +3 Query: 207 VGEGTFGRVYXSQF-NDGXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHPNLNELVGY 383 +GEGT+G VY + + G V+A+KK+ V VS + L HPN+ L+ Sbjct: 10 IGEGTYGVVYKGRHKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQELKHPNVVRLLDV 69 Query: 384 CMEHGXHLLVYDF 422 M+ L+++F Sbjct: 70 LMQESRLYLIFEF 82
>CDC2_ORYCU (Q9DGA5) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 37.7 bits (86), Expect = 0.015 Identities = 23/73 (31%), Positives = 37/73 (50%), Gaps = 1/73 (1%) Frame = +3 Query: 207 VGEGTFGRVYXSQF-NDGXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHPNLNELVGY 383 +GEGT+G VY + + G V+A+KK+ V VS + L HPN+ L+ Sbjct: 10 IGEGTYGVVYKGRHKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQELKHPNVVRLLDV 69 Query: 384 CMEHGXHLLVYDF 422 M+ L+++F Sbjct: 70 LMQESRLYLIFEF 82
>TIE2_BRARE (O73791) Tyrosine-protein kinase receptor Tie-2 precursor (EC| 2.7.10.1) Length = 1116 Score = 37.7 bits (86), Expect = 0.015 Identities = 28/94 (29%), Positives = 46/94 (48%), Gaps = 7/94 (7%) Frame = +3 Query: 201 NLVGEGTFGRVYXSQFN-DGXVL--AVKKLDCTVIPFQSSDDFVELVSXISIL----HHP 359 +++GEG FG+V ++ DG + AVK++ + S DD + + +L H Sbjct: 820 DVLGEGNFGQVLKARIRKDGLRMDAAVKRMK----DYASQDDHRDFAGELEVLCRLGPHK 875 Query: 360 NLNELVGYCMEHGXHLLVYDFHRNGSLHDLLHLS 461 N+ L+G C G L +F +G+L D L S Sbjct: 876 NIIHLLGACEHRGYLYLAIEFAPHGNLLDFLRKS 909
>JAK1_HUMAN (P23458) Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1)| (JAK-1) Length = 1142 Score = 37.7 bits (86), Expect = 0.015 Identities = 30/91 (32%), Positives = 44/91 (48%), Gaps = 9/91 (9%) Frame = +3 Query: 207 VGEGTFGRV----YXSQFNDGXVLAVKKLDCTVIPFQSSDDFVELVSXISIL---HHPNL 365 +GEG FG+V Y + N G +AVK L P + +L I IL +H N+ Sbjct: 870 LGEGHFGKVELCRYDPEDNTGEQVAVKSLK----PESGGNHIADLKKEIEILRNLYHENI 925 Query: 366 NELVGYCMEHGXH--LLVYDFHRNGSLHDLL 452 + G C E G + L+ +F +GSL + L Sbjct: 926 VKYKGICTEDGGNGIKLIMEFLPSGSLKEYL 956
>TESK1_RAT (Q63572) Dual specificity testis-specific protein kinase 1 (EC| 2.7.12.1) (Testicular protein kinase 1) Length = 628 Score = 37.7 bits (86), Expect = 0.015 Identities = 24/90 (26%), Positives = 40/90 (44%) Frame = +3 Query: 183 DSFSMDNLVGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHPN 362 D F +G G F VY + + V K++ +P S+ E V ++ L HPN Sbjct: 50 DDFDCAEKIGAGFFSEVYKVRHRQSGQVMVLKMN--KLPSNRSNTLRE-VQLMNRLRHPN 106 Query: 363 LNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 + +G C+ G + ++ G+L LL Sbjct: 107 ILRFMGVCVHQGQLHALTEYMNGGTLEQLL 136
>LYN_RAT (Q07014) Tyrosine-protein kinase Lyn (EC 2.7.10.2)| Length = 511 Score = 37.7 bits (86), Expect = 0.015 Identities = 25/94 (26%), Positives = 42/94 (44%) Frame = +3 Query: 171 QIATDSFSMDNLVGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSSDDFVELVSXISIL 350 +I +S + +G G FG V+ +N+ +AVK L + S+ F+E + + L Sbjct: 240 EIPRESIKLVKKLGAGQFGEVWMGYYNNSTKVAVKTLKPGTM---SAQAFLEEANLMKTL 296 Query: 351 HHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 H L L + ++ +F GSL D L Sbjct: 297 QHDKLVRLYAVVTKEEPIYIITEFMAKGSLLDFL 330
>FYN_MOUSE (P39688) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 533 Score = 37.7 bits (86), Expect = 0.015 Identities = 25/94 (26%), Positives = 44/94 (46%) Frame = +3 Query: 171 QIATDSFSMDNLVGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSSDDFVELVSXISIL 350 ++A DS ++ +G+G F V+ +N +A+K L + S + F+E + L Sbjct: 261 EVARDSLFLEKKLGQGCFAEVWLGTWNGNTKVAIKTLKPGTM---SPESFLEEAQIMKKL 317 Query: 351 HHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 H L +L E + +V ++ GSL D L Sbjct: 318 KHDKLVQLYAVVSEEPIY-IVTEYMSKGSLLDFL 350
>M3K7_MOUSE (Q62073) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1) Length = 579 Score = 37.4 bits (85), Expect = 0.019 Identities = 25/95 (26%), Positives = 49/95 (51%) Frame = +3 Query: 171 QIATDSFSMDNLVGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSSDDFVELVSXISIL 350 +I ++ +VG G FG V +++ V A+K+++ F+ + +S + Sbjct: 30 EIDYKEIEVEEVVGRGAFGVVCKAKWRAKDV-AIKQIESE----SERKAFIVELRQLSRV 84 Query: 351 HHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLLH 455 +HPN+ +L G C+ LV ++ GSL+++LH Sbjct: 85 NHPNIVKLYGACL--NPVCLVMEYAEGGSLYNVLH 117
>ATG1_NEUCR (Q7RX99) Serine/threonine-protein kinase atg-1 (EC 2.7.11.1)| (Autophagy-related protein 1) Length = 932 Score = 37.4 bits (85), Expect = 0.019 Identities = 23/90 (25%), Positives = 46/90 (51%), Gaps = 2/90 (2%) Frame = +3 Query: 177 ATDSFSMDNLVGEGTFGRVYXSQFN-DGXVLAVKKLDCTVIPFQSSDDFVELVSXISILH 353 A SF +D +G+G+F +VY + G ++AVK ++ + + ++ + + L Sbjct: 20 AIGSFVIDQEIGKGSFAKVYLGRHKVTGALVAVKSVELARLNKKLKENLYGEIQILKTLR 79 Query: 354 HPNLNELVGYCMEHGXHL-LVYDFHRNGSL 440 HP++ L C+E H+ L+ ++ G L Sbjct: 80 HPHIVALHD-CVESSTHINLIMEYCELGDL 108
>SRC_RSVP (P00526) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 37.4 bits (85), Expect = 0.019 Identities = 24/94 (25%), Positives = 46/94 (48%) Frame = +3 Query: 171 QIATDSFSMDNLVGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSSDDFVELVSXISIL 350 +I +S ++ +G+G FG V+ +ND +A+K L + S + F++ + L Sbjct: 260 EIPRESLRLEAKLGQGCFGEVWMGTWNDTTRVAIKTLKPGTM---SPEAFLQEAQVMKKL 316 Query: 351 HHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 H L +L E ++++ ++ GSL D L Sbjct: 317 RHEKLVQLYAVVSEEPIYIVI-EYMSKGSLLDFL 349
>BMX_MOUSE (P97504) Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2)| (Bone marrow tyrosine kinase gene in chromosome X protein homolog) Length = 651 Score = 37.4 bits (85), Expect = 0.019 Identities = 29/115 (25%), Positives = 51/115 (44%) Frame = +3 Query: 108 PVAXKSNTKPXKAIVYSVADLQIATDSFSMDNLVGEGTFGRVYXSQFNDGXVLAVKKLDC 287 PV+ K+N P + S ++ + ++ +G G FG V Q+ +AVK + Sbjct: 367 PVSTKANKVPVSVALGS-GIWELKREEITLLKELGNGQFGVVQLGQWKGQYDVAVKMIKE 425 Query: 288 TVIPFQSSDDFVELVSXISILHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 + S D+F + + L HP L + G C + +V ++ NG L + L Sbjct: 426 GAM---SEDEFFQEAQTMMKLSHPKLVKFYGVCSKKYPIYIVTEYITNGCLLNYL 477
>TEC_MOUSE (P24604) Tyrosine-protein kinase Tec (EC 2.7.10.2)| Length = 630 Score = 37.4 bits (85), Expect = 0.019 Identities = 29/115 (25%), Positives = 48/115 (41%) Frame = +3 Query: 108 PVAXKSNTKPXKAIVYSVADLQIATDSFSMDNLVGEGTFGRVYXSQFNDGXVLAVKKLDC 287 PV+ K P A +S +I + +G G FG V ++ +A+K + Sbjct: 343 PVSTKGKNAPTTA-GFSYDKWEINPSELTFMRELGSGLFGVVRLGKWRAQYKVAIKAIRE 401 Query: 288 TVIPFQSSDDFVELVSXISILHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 + +DF+E + L HP L +L G C + +V +F G L + L Sbjct: 402 GAM---CEEDFIEEAKVMMKLTHPKLVQLYGVCTQQKPIYIVTEFMERGCLLNFL 453
>TEC_HUMAN (P42680) Tyrosine-protein kinase Tec (EC 2.7.10.2)| Length = 631 Score = 37.4 bits (85), Expect = 0.019 Identities = 29/115 (25%), Positives = 48/115 (41%) Frame = +3 Query: 108 PVAXKSNTKPXKAIVYSVADLQIATDSFSMDNLVGEGTFGRVYXSQFNDGXVLAVKKLDC 287 PV+ K P A +S +I + +G G FG V ++ +A+K + Sbjct: 344 PVSVKGKNAPTTA-GFSYEKWEINPSELTFMRELGSGLFGVVRLGKWRAQYKVAIKAIRE 402 Query: 288 TVIPFQSSDDFVELVSXISILHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 + +DF+E + L HP L +L G C + +V +F G L + L Sbjct: 403 GAM---CEEDFIEEAKVMMKLTHPKLVQLYGVCTQQKPIYIVTEFMERGCLLNFL 454
>CDC2_CHICK (P13863) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 37.4 bits (85), Expect = 0.019 Identities = 22/73 (30%), Positives = 36/73 (49%), Gaps = 1/73 (1%) Frame = +3 Query: 207 VGEGTFGRVYXSQFND-GXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHPNLNELVGY 383 +GEGT+G VY + G V+A+KK+ + +S + LHHPN+ L Sbjct: 10 IGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELHHPNIVCLQDV 69 Query: 384 CMEHGXHLLVYDF 422 M+ L+++F Sbjct: 70 LMQDARLYLIFEF 82
>MERTK_RAT (P57097) Proto-oncogene tyrosine-protein kinase MER precursor (EC| 2.7.10.1) (C-mer) (Receptor tyrosine kinase MerTK) Length = 994 Score = 37.4 bits (85), Expect = 0.019 Identities = 25/105 (23%), Positives = 47/105 (44%), Gaps = 9/105 (8%) Frame = +3 Query: 165 DLQIATDSFSMDNLVGEGTFGRVYXSQFN--DGXV--LAVKKLDCTVIPFQSSDDFVELV 332 D+ + + + ++GEG FG V DG +AVK + + ++F+ Sbjct: 574 DVVVDRNLLILGKVLGEGEFGSVMEGNLKQEDGTSQKVAVKTMKLDNFSLREIEEFLSEA 633 Query: 333 SXISILHHPNLNELVGYCMEHGXH-----LLVYDFHRNGSLHDLL 452 + + +HPN+ L+G C+E +++ F + G LH L Sbjct: 634 ACMKDFNHPNVIRLLGVCIELSSQGIPKPMVILPFMKYGDLHTFL 678
>IRAK3_MOUSE (Q8K4B2) Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1)| (IRAK-3) (IL-1 receptor-associated kinase M) (IRAK-M) Length = 609 Score = 37.4 bits (85), Expect = 0.019 Identities = 26/96 (27%), Positives = 42/96 (43%), Gaps = 1/96 (1%) Frame = +3 Query: 180 TDSFSMDNLVGEGTFGRVYXSQF-NDGXVLAVKKLDCTVIPFQSSDDFVELVSXISILHH 356 T F D L+GEG VY N + + K + + + F+ + + + H Sbjct: 175 TKHFHKDFLIGEGEIFEVYRVDIRNQAYAVKLFKQEKKMQLKKHWKRFLSELEVLLLFRH 234 Query: 357 PNLNELVGYCMEHGXHLLVYDFHRNGSLHDLLHLSD 464 P++ EL Y E LVY + NG+L D L ++ Sbjct: 235 PHILELAAYFTETEKLCLVYPYMSNGTLFDRLQCTN 270
>CDC2_CARAU (P51958) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 302 Score = 37.4 bits (85), Expect = 0.019 Identities = 24/81 (29%), Positives = 38/81 (46%), Gaps = 1/81 (1%) Frame = +3 Query: 183 DSFSMDNLVGEGTFGRVYXSQFND-GXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHP 359 D + +GEGT+G VY + G V+A+KK+ V +S + L HP Sbjct: 2 DDYLKIEKIGEGTYGVVYKGRNKTTGQVVAMKKIRLESEEEGVPSTAVREISLLKELQHP 61 Query: 360 NLNELVGYCMEHGXHLLVYDF 422 N+ L+ M+ LV++F Sbjct: 62 NVVRLLDVLMQESKLYLVFEF 82
>MERTK_HUMAN (Q12866) Proto-oncogene tyrosine-protein kinase MER precursor (EC| 2.7.10.1) (C-mer) (Receptor tyrosine kinase MerTK) Length = 999 Score = 37.4 bits (85), Expect = 0.019 Identities = 27/105 (25%), Positives = 46/105 (43%), Gaps = 9/105 (8%) Frame = +3 Query: 165 DLQIATDSFSMDNLVGEGTFGRVYXSQFN--DGXVL--AVKKLDCTVIPFQSSDDFVELV 332 D+ I + + ++GEG FG V DG L AVK + + ++F+ Sbjct: 579 DVVIDRNLLILGKILGEGEFGSVMEGNLKQEDGTSLKVAVKTMKLDNSSHREIEEFLSEA 638 Query: 333 SXISILHHPNLNELVGYCMEHGXH-----LLVYDFHRNGSLHDLL 452 + + HPN+ L+G C+E +++ F + G LH L Sbjct: 639 ACMKDFSHPNVIRLLGVCIEMSSQGIPKPMVILPFMKYGDLHTYL 683
>M4K3_RAT (Q924I2) Mitogen-activated protein kinase kinase kinase kinase 3| (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 3) (MEK kinase kinase 3) (MEKKK 3) (Germinal center kinase-related protein kinase) (GLK) (Fragment) Length = 862 Score = 37.4 bits (85), Expect = 0.019 Identities = 25/97 (25%), Positives = 45/97 (46%), Gaps = 4/97 (4%) Frame = +3 Query: 183 DSFSMDNLVGEGTFGRVYXSQ-FNDGXVLAVKKLDCTVIPFQSSDDFVELVSXISIL--- 350 + F + +G GT+G VY ++ N G + A+K VI + +DF + I ++ Sbjct: 3 EDFELIQRIGSGTYGDVYKARNVNTGELAAIK-----VIKLEPGEDFAVVQQEIIMMKDC 57 Query: 351 HHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLLHLS 461 H N+ G + + +F GSL D+ H++ Sbjct: 58 KHANIVAYFGSYLRRDKLWICMEFCGGGSLQDIYHVT 94
>M3K7_HUMAN (O43318) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1) Length = 606 Score = 37.4 bits (85), Expect = 0.019 Identities = 25/95 (26%), Positives = 49/95 (51%) Frame = +3 Query: 171 QIATDSFSMDNLVGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSSDDFVELVSXISIL 350 +I ++ +VG G FG V +++ V A+K+++ F+ + +S + Sbjct: 30 EIDYKEIEVEEVVGRGAFGVVCKAKWRAKDV-AIKQIESE----SERKAFIVELRQLSRV 84 Query: 351 HHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLLH 455 +HPN+ +L G C+ LV ++ GSL+++LH Sbjct: 85 NHPNIVKLYGACL--NPVCLVMEYAEGGSLYNVLH 117
>CDC2H_PLACH (Q4Y4B1) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 288 Score = 37.0 bits (84), Expect = 0.025 Identities = 26/87 (29%), Positives = 42/87 (48%), Gaps = 1/87 (1%) Frame = +3 Query: 207 VGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHPNLNELVGYC 386 +GEGT+G VY +Q +DG A+KK+ + +S + L H N+ +L Y Sbjct: 10 IGEGTYGVVYKAQNSDGESFALKKIRLEKEDEGIPSTAIREISILKELRHSNIVKL--YD 67 Query: 387 MEHGXHLLVYDF-HRNGSLHDLLHLSD 464 + H L+ F H + L L+ + D Sbjct: 68 VIHAKKRLILVFEHLDQDLKKLIDVCD 94
>CDC2H_PLABA (Q4Z6R1) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 288 Score = 37.0 bits (84), Expect = 0.025 Identities = 26/87 (29%), Positives = 42/87 (48%), Gaps = 1/87 (1%) Frame = +3 Query: 207 VGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHPNLNELVGYC 386 +GEGT+G VY +Q +DG A+KK+ + +S + L H N+ +L Y Sbjct: 10 IGEGTYGVVYKAQNSDGESFALKKIRLEKEDEGIPSTAIREISILKELRHSNIVKL--YD 67 Query: 387 MEHGXHLLVYDF-HRNGSLHDLLHLSD 464 + H L+ F H + L L+ + D Sbjct: 68 VIHAKKRLILVFEHLDQDLKKLIDVCD 94
>ABL1_HUMAN (P00519) Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2)| (p150) (c-ABL) (Abelson murine leukemia viral oncogene homolog 1) Length = 1130 Score = 37.0 bits (84), Expect = 0.025 Identities = 28/112 (25%), Positives = 51/112 (45%), Gaps = 5/112 (4%) Frame = +3 Query: 132 KPXKAIVYSVAD----LQIATDSFSMDNLVGEGTFGRVYXSQFND-GXVLAVKKLDCTVI 296 K K VY V+ ++ +M + +G G +G VY + +AVK L + Sbjct: 219 KRNKPTVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTM 278 Query: 297 PFQSSDDFVELVSXISILHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 + +F++ + + + HPNL +L+G C ++ +F G+L D L Sbjct: 279 EVE---EFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYL 327
>SSK22_YEAST (P25390) Serine/threonine-protein kinase SSK22 (EC 2.7.11.1) (MAP| kinase kinase kinase SSK22) (Suppressor of sensor kinase 22) Length = 1331 Score = 37.0 bits (84), Expect = 0.025 Identities = 25/87 (28%), Positives = 44/87 (50%), Gaps = 3/87 (3%) Frame = +3 Query: 201 NLVGEGTFGRVYXS-QFNDGXVLAVK--KLDCTVIPFQSSDDFVELVSXISILHHPNLNE 371 + +G GTFG+VY + +G +LAVK K+ T + E ++ + +L+HPN+ + Sbjct: 1038 SFIGGGTFGQVYSAINLENGEILAVKEIKIHDTTTMKKIFPLIKEEMTVLEMLNHPNIVQ 1097 Query: 372 LVGYCMEHGXHLLVYDFHRNGSLHDLL 452 G + + ++ GSL LL Sbjct: 1098 YYGVEVHRDKVNIFMEYCEGGSLASLL 1124
>ATG1_BOTCI (Q6H9I1) Serine/threonine-protein kinase ATG1 (EC 2.7.11.1)| (Autophagy-related protein 1) (Botryotinia fuckeliana putative kinase exons 1-3) Length = 952 Score = 37.0 bits (84), Expect = 0.025 Identities = 21/87 (24%), Positives = 47/87 (54%), Gaps = 2/87 (2%) Frame = +3 Query: 186 SFSMDNLVGEGTFGRVYX-SQFNDGXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHPN 362 SF+++ +G+G+F VY + G ++A+K ++ + + + D+ + + L+HP+ Sbjct: 22 SFTINEQIGKGSFATVYRGTHMPSGNLVAIKSVNLSRLNKKLKDNLYVEIEILKSLYHPH 81 Query: 363 LNELVGYCMEHGXHL-LVYDFHRNGSL 440 + L+ C E H+ L+ ++ G L Sbjct: 82 IVALID-CRESASHIHLMMEYCELGDL 107
>ABL_FSVHY (P10447) Tyrosine-protein kinase transforming protein Abl (EC| 2.7.10.2) (V-abl) Length = 439 Score = 37.0 bits (84), Expect = 0.025 Identities = 28/112 (25%), Positives = 51/112 (45%), Gaps = 5/112 (4%) Frame = +3 Query: 132 KPXKAIVYSVAD----LQIATDSFSMDNLVGEGTFGRVYXSQFND-GXVLAVKKLDCTVI 296 K K VY V+ ++ +M + +G G +G VY + +AVK L + Sbjct: 168 KRNKPTVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTM 227 Query: 297 PFQSSDDFVELVSXISILHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 + +F++ + + + HPNL +L+G C ++ +F G+L D L Sbjct: 228 EVE---EFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYL 276
>CDK2_XENLA (P23437) Cell division protein kinase 2 (EC 2.7.11.22) (CDC2| homolog Eg1 protein kinase) Length = 297 Score = 37.0 bits (84), Expect = 0.025 Identities = 21/81 (25%), Positives = 41/81 (50%), Gaps = 1/81 (1%) Frame = +3 Query: 183 DSFSMDNLVGEGTFGRVYXSQFND-GXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHP 359 ++F +GEGT+G VY ++ + G ++A+KK+ + +S + L+HP Sbjct: 2 ENFQKVEKIGEGTYGVVYKARNRETGEIVALKKIRLDTETEGVPSTAIREISLLKELNHP 61 Query: 360 NLNELVGYCMEHGXHLLVYDF 422 N+ +L+ LV++F Sbjct: 62 NIVKLLDVIHTENKLYLVFEF 82
>CC2H3_TRYBB (P54666) Cell division control protein 2 homolog 3 (EC 2.7.11.22)| Length = 311 Score = 37.0 bits (84), Expect = 0.025 Identities = 21/81 (25%), Positives = 41/81 (50%), Gaps = 1/81 (1%) Frame = +3 Query: 183 DSFSMDNLVGEGTFGRVYXSQFN-DGXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHP 359 D ++ +++GEGT+G VY + G ++A+KK+ + VS + +HHP Sbjct: 21 DRYNRMDILGEGTYGVVYRAVDRATGQIVALKKVRLDRTDEGIPQTALREVSILQEIHHP 80 Query: 360 NLNELVGYCMEHGXHLLVYDF 422 N+ L+ G L++++ Sbjct: 81 NIVNLLDVICADGKLYLIFEY 101
>FER_HUMAN (P16591) Proto-oncogene tyrosine-protein kinase FER (EC 2.7.10.2)| (p94-FER) (c-FER) Length = 822 Score = 37.0 bits (84), Expect = 0.025 Identities = 19/66 (28%), Positives = 32/66 (48%) Frame = +3 Query: 195 MDNLVGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHPNLNEL 374 + L+G+G FG VY D +AVK +P + F++ + HPN+ +L Sbjct: 565 LGELLGKGNFGEVYKGTLKDKTSVAVKTCK-EDLPQELKIKFLQEAKILKQYDHPNIVKL 623 Query: 375 VGYCME 392 +G C + Sbjct: 624 IGVCTQ 629
>KYK2_DICDI (P18161) Tyrosine-protein kinase 2 (EC 2.7.10.2) (Fragment)| Length = 410 Score = 37.0 bits (84), Expect = 0.025 Identities = 23/83 (27%), Positives = 41/83 (49%) Frame = +3 Query: 207 VGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHPNLNELVGYC 386 VGEG F V+ + G +A+KKL Q + F+ V + +H N+ +G C Sbjct: 114 VGEGAFSEVWEGWWK-GIHVAIKKLKIIGDEEQFKERFIREVQNLKKGNHQNIVMFIGAC 172 Query: 387 MEHGXHLLVYDFHRNGSLHDLLH 455 + ++ ++ GSL+++LH Sbjct: 173 YKPA--CIITEYMAGGSLYNILH 193
>NTRK3_CHICK (Q91044) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (Trk-C) Length = 827 Score = 37.0 bits (84), Expect = 0.025 Identities = 22/88 (25%), Positives = 45/88 (51%), Gaps = 6/88 (6%) Frame = +3 Query: 207 VGEGTFGRVYXSQF------NDGXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHPNLN 368 +GEG FG+V+ ++ ND ++AVK L + + DF ++ L H ++ Sbjct: 546 LGEGAFGKVFLAECYNLSPTNDKMLVAVKALKDPTLAARK--DFQREAELLTNLQHEHIV 603 Query: 369 ELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 + G C + ++V+++ ++G L+ L Sbjct: 604 KFYGVCGDGDPLIMVFEYMKHGDLNKFL 631
>YES_XIPHE (P27447) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 543 Score = 37.0 bits (84), Expect = 0.025 Identities = 28/98 (28%), Positives = 44/98 (44%) Frame = +3 Query: 171 QIATDSFSMDNLVGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSSDDFVELVSXISIL 350 +I +S +D +G+G FG V+ +N +A+K L + S + F+E + L Sbjct: 271 EIPRESLRLDVRLGQGCFGEVWMGTWNGTTKVAIKTLKPGTM---SPEAFLEEAQIMKKL 327 Query: 351 HHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLLHLSD 464 H L L E + +V +F GSL D L D Sbjct: 328 RHDKLVPLYAVVSEEPIY-IVTEFMGKGSLLDFLKEGD 364
>CDC7_SCHPO (P41892) Cell division control protein 7 (EC 2.7.11.1)| Length = 1062 Score = 37.0 bits (84), Expect = 0.025 Identities = 22/93 (23%), Positives = 42/93 (45%), Gaps = 1/93 (1%) Frame = +3 Query: 174 IATDSFSMDNLVGEGTFGRVYXS-QFNDGXVLAVKKLDCTVIPFQSSDDFVELVSXISIL 350 I S ++ + +G+G FG VY +G +AVKK+ + + + + L Sbjct: 4 IQASSITLGDCLGKGAFGAVYRGLNIKNGETVAVKKVKLSKMLKSDLSVIKMEIDLLKNL 63 Query: 351 HHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDL 449 HPN+ + G + ++ ++ NGSL + Sbjct: 64 DHPNIVKYRGSYQTNDSLCIILEYCENGSLRSI 96
>LYN_HUMAN (P07948) Tyrosine-protein kinase Lyn (EC 2.7.10.2)| Length = 511 Score = 36.6 bits (83), Expect = 0.033 Identities = 24/94 (25%), Positives = 41/94 (43%) Frame = +3 Query: 171 QIATDSFSMDNLVGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSSDDFVELVSXISIL 350 +I +S + +G G FG V+ +N+ +AVK L + Q+ F+E + + L Sbjct: 240 EIPRESIKLVKRLGAGQFGEVWMGYYNNSTKVAVKTLKPGTMSVQA---FLEEANLMKTL 296 Query: 351 HHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 H L L ++ ++ GSL D L Sbjct: 297 QHDKLVRLYAVVTREEPIYIITEYMAKGSLLDFL 330
>DDR1_MOUSE (Q03146) Epithelial discoidin domain-containing receptor 1| precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (Protei Length = 911 Score = 36.6 bits (83), Expect = 0.033 Identities = 28/101 (27%), Positives = 46/101 (45%), Gaps = 19/101 (18%) Frame = +3 Query: 207 VGEGTFGRVYXSQFNDGX-----------------VLAVKKL--DCTVIPFQSSDDFVEL 329 +GEG FG V+ + D ++AVK L D T + +DF++ Sbjct: 614 LGEGQFGEVHLCEVEDPQDLVSSDFPISVHKGHPLLVAVKILRPDATK---NARNDFLKE 670 Query: 330 VSXISILHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 V +S L PN+ L+G C++ ++ D+ NG L+ L Sbjct: 671 VKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFL 711
>ABL1_MOUSE (P00520) Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2)| (p150) (c-ABL) (Abelson murine leukemia viral oncogene homolog 1) Length = 1123 Score = 36.6 bits (83), Expect = 0.033 Identities = 27/112 (24%), Positives = 51/112 (45%), Gaps = 5/112 (4%) Frame = +3 Query: 132 KPXKAIVYSVAD----LQIATDSFSMDNLVGEGTFGRVYXSQFND-GXVLAVKKLDCTVI 296 K K +Y V+ ++ +M + +G G +G VY + +AVK L + Sbjct: 219 KRNKPTIYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTM 278 Query: 297 PFQSSDDFVELVSXISILHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 + +F++ + + + HPNL +L+G C ++ +F G+L D L Sbjct: 279 EVE---EFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYL 327
>M3K3_ARATH (O22042) Mitogen-activated protein kinase kinase kinase 3 (EC| 2.7.11.25) (Arabidospsis NPK1-related protein kinase 3) Length = 651 Score = 36.6 bits (83), Expect = 0.033 Identities = 27/92 (29%), Positives = 43/92 (46%), Gaps = 9/92 (9%) Frame = +3 Query: 204 LVGEGTFGRVYXSQ-FNDGXVLAVKKLDCTVIPFQSSDD--------FVELVSXISILHH 356 L+G G FGRVY + G +LA+K++ + P +S + E V + L H Sbjct: 73 LIGCGAFGRVYMGMNLDSGELLAIKQV--LIAPSSASKEKTQGHIRELEEEVQLLKNLSH 130 Query: 357 PNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 PN+ +G E ++ +F GS+ LL Sbjct: 131 PNIVRYLGTVRESDSLNILMEFVPGGSISSLL 162
>JAK_DROME (Q24592) Tyrosine-protein kinase hopscotch (EC 2.7.10.2)| Length = 1177 Score = 36.6 bits (83), Expect = 0.033 Identities = 24/89 (26%), Positives = 46/89 (51%), Gaps = 6/89 (6%) Frame = +3 Query: 189 FSMDNLVGEGTFGRVYXS--QFND----GXVLAVKKLDCTVIPFQSSDDFVELVSXISIL 350 ++M+N++G G +G VY +FND +A+K L+ Q S DF + + L Sbjct: 892 YNMENMIGRGHYGTVYKGHLEFNDKDQPREQVAIKMLN----TMQVSTDFHREIGIMRTL 947 Query: 351 HHPNLNELVGYCMEHGXHLLVYDFHRNGS 437 HPN+ + + + H ++ ++ ++GS Sbjct: 948 SHPNIVKFKYWAEK--SHCIIMEYLQSGS 974
>ABL_MLVAB (P00521) Tyrosine-protein kinase transforming protein Abl (EC| 2.7.10.2) (V-abl) Length = 746 Score = 36.6 bits (83), Expect = 0.033 Identities = 27/112 (24%), Positives = 51/112 (45%), Gaps = 5/112 (4%) Frame = +3 Query: 132 KPXKAIVYSVAD----LQIATDSFSMDNLVGEGTFGRVYXSQFND-GXVLAVKKLDCTVI 296 K K +Y V+ ++ +M + +G G +G VY + +AVK L + Sbjct: 105 KRNKPTIYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTM 164 Query: 297 PFQSSDDFVELVSXISILHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 + +F++ + + + HPNL +L+G C ++ +F G+L D L Sbjct: 165 EVE---EFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYL 213
>MERTK_MOUSE (Q60805) Proto-oncogene tyrosine-protein kinase MER precursor (EC| 2.7.10.1) (C-mer) (Receptor tyrosine kinase MerTK) Length = 994 Score = 36.6 bits (83), Expect = 0.033 Identities = 26/105 (24%), Positives = 47/105 (44%), Gaps = 9/105 (8%) Frame = +3 Query: 165 DLQIATDSFSMDNLVGEGTFGRVYXSQFN--DGXV--LAVKKLDCTVIPFQSSDDFVELV 332 D+ I + + ++GEG FG V DG +AVK + + ++F+ Sbjct: 574 DVVIDRNLLVLGKVLGEGEFGSVMEGNLKQEDGTSQKVAVKTMKLDNFSQREIEEFLSEA 633 Query: 333 SXISILHHPNLNELVGYCMEHGXH-----LLVYDFHRNGSLHDLL 452 + + +HPN+ L+G C+E +++ F + G LH L Sbjct: 634 ACMKDFNHPNVIRLLGVCIELSSQGIPKPMVILPFMKYGDLHTFL 678
>M3K1_ARATH (O22040) Mitogen-activated protein kinase kinase kinase 1 (EC| 2.7.11.25) (Arabidospsis NPK1-related protein kinase 1) Length = 666 Score = 36.6 bits (83), Expect = 0.033 Identities = 28/99 (28%), Positives = 46/99 (46%), Gaps = 10/99 (10%) Frame = +3 Query: 186 SFSMDNLVGEGTFGRVYXSQ-FNDGXVLAVKKL---------DCTVIPFQSSDDFVELVS 335 S+ L+G G FG VY + G +LAVK++ + T Q ++ V+L+ Sbjct: 68 SWRKGQLIGRGAFGTVYMGMNLDSGELLAVKQVLIAANFASKEKTQAHIQELEEEVKLLK 127 Query: 336 XISILHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 +S HPN+ +G E ++ +F GS+ LL Sbjct: 128 NLS---HPNIVRYLGTVREDDTLNILLEFVPGGSISSLL 163
>EPHA3_MOUSE (P29319) Ephrin type-A receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ETK1) (MEK4) Length = 983 Score = 36.6 bits (83), Expect = 0.033 Identities = 27/102 (26%), Positives = 43/102 (42%), Gaps = 4/102 (3%) Frame = +3 Query: 171 QIATDSFSMDNLVGEGTFGRVYXSQFN----DGXVLAVKKLDCTVIPFQSSDDFVELVSX 338 ++ + S+D +VG G FG V + +A+K L Q D F+ S Sbjct: 615 ELDATNISIDKVVGAGEFGEVCSGRLKLPSKKEISVAIKTLKVGYTEKQRRD-FLGEASI 673 Query: 339 ISILHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLLHLSD 464 + HPN+ L G + ++V ++ NGSL L D Sbjct: 674 MGQFDHPNIIRLEGVVTKSKPEMIVTEYMENGSLDSFLRKHD 715
>CDC22_XENLA (P24033) Cell division control protein 2 homolog 2 (EC 2.7.11.22)| (EC 2.7.11.23) (p34 protein kinase 2) Length = 302 Score = 36.6 bits (83), Expect = 0.033 Identities = 22/81 (27%), Positives = 39/81 (48%), Gaps = 1/81 (1%) Frame = +3 Query: 183 DSFSMDNLVGEGTFGRVYXSQFN-DGXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHP 359 D ++ +GEGT+G VY + G V+A+KK+ + +S + L HP Sbjct: 2 DEYTKIEKIGEGTYGVVYKGRHKATGQVVAMKKIRLENEEEGVPSTAIREISLLKELQHP 61 Query: 360 NLNELVGYCMEHGXHLLVYDF 422 N+ L+ M+ L+++F Sbjct: 62 NIVCLLDVLMQDSRLYLIFEF 82
>CDC21_XENLA (P35567) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| (EC 2.7.11.23) (p34 protein kinase 1) Length = 302 Score = 36.6 bits (83), Expect = 0.033 Identities = 22/81 (27%), Positives = 39/81 (48%), Gaps = 1/81 (1%) Frame = +3 Query: 183 DSFSMDNLVGEGTFGRVYXSQFN-DGXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHP 359 D ++ +GEGT+G VY + G V+A+KK+ + +S + L HP Sbjct: 2 DEYTKIEKIGEGTYGVVYKGRHKATGQVVAMKKIRLENEEEGVPSTAIREISLLKELQHP 61 Query: 360 NLNELVGYCMEHGXHLLVYDF 422 N+ L+ M+ L+++F Sbjct: 62 NIVCLLDVLMQDSRLYLIFEF 82
>NTRK1_CHICK (Q91009) High affinity nerve growth factor receptor precursor (EC| 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (Trk-A) (Fragment) Length = 778 Score = 36.6 bits (83), Expect = 0.033 Identities = 21/88 (23%), Positives = 46/88 (52%), Gaps = 6/88 (6%) Frame = +3 Query: 207 VGEGTFGRVYXSQFN------DGXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHPNLN 368 +GEG FG+V+ ++ + + ++AVK L + + DF +++L H ++ Sbjct: 499 LGEGAFGKVFLAECSHLLPEQEKTLVAVKALK--EVTENARLDFQREAELLTVLQHEHIV 556 Query: 369 ELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 + G C E ++V+++ ++G L+ L Sbjct: 557 KFYGVCTEGDPLIMVFEYMKHGDLNRFL 584
>LET23_CAEEL (P24348) Receptor tyrosine-protein kinase let-23 precursor (EC| 2.7.10.1) (Lethal protein 23) Length = 1367 Score = 36.6 bits (83), Expect = 0.033 Identities = 24/92 (26%), Positives = 44/92 (47%), Gaps = 4/92 (4%) Frame = +3 Query: 195 MDNLVGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQS----SDDFVELVSXISILHHPN 362 +D +G G FG V+ + VK + + FQ+ +D+ +E + + L H N Sbjct: 931 LDKKLGAGAFGTVFAGIYYPKRAKNVK-IPVAIKVFQTDQSQTDEMLEEATNMFRLRHDN 989 Query: 363 LNELVGYCMEHGXHLLVYDFHRNGSLHDLLHL 458 L +++G+CM +V + G+L + L L Sbjct: 990 LLKIIGFCMHDDGLKIVTIYRPLGNLQNFLKL 1021
>CDK2_MOUSE (P97377) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 346 Score = 36.2 bits (82), Expect = 0.043 Identities = 22/81 (27%), Positives = 40/81 (49%), Gaps = 1/81 (1%) Frame = +3 Query: 183 DSFSMDNLVGEGTFGRVYXSQFN-DGXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHP 359 ++F +GEGT+G VY ++ G V+A+KK+ + +S + L+HP Sbjct: 2 ENFQKVEKIGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHP 61 Query: 360 NLNELVGYCMEHGXHLLVYDF 422 N+ +L+ LV++F Sbjct: 62 NIVKLLDVIHTENKLYLVFEF 82
>MARK1_RAT (O08678) Serine/threonine-protein kinase MARK1 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 1) Length = 793 Score = 36.2 bits (82), Expect = 0.043 Identities = 27/114 (23%), Positives = 49/114 (42%), Gaps = 1/114 (0%) Frame = +3 Query: 114 AXKSNTKPXKAIVYSVADLQIATDSFSMDNLVGEGTFGRVYXSQFN-DGXVLAVKKLDCT 290 + + N + + S D Q ++ + +G+G F +V ++ G +AVK +D T Sbjct: 35 SSRQNIPRCRNSITSATDEQPHIGNYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKT 94 Query: 291 VIPFQSSDDFVELVSXISILHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 + S V + IL+HPN+ +L LV ++ G + D L Sbjct: 95 QLNPTSLQKLFREVRIMKILNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYL 148
>FGFR1_XENLA (P22182) Fibroblast growth factor receptor 1 precursor (EC| 2.7.10.1) (FGFR-1) Length = 812 Score = 36.2 bits (82), Expect = 0.043 Identities = 26/102 (25%), Positives = 44/102 (43%), Gaps = 8/102 (7%) Frame = +3 Query: 171 QIATDSFSMDNLVGEGTFGRVYXSQF--------NDGXVLAVKKLDCTVIPFQSSDDFVE 326 ++A D + +GEG FG+V ++ N +AVK L SD E Sbjct: 466 EVARDRLILGKPLGEGCFGQVVMAEAIGLDKEKPNKVTKVAVKMLKSDASEKDLSDLISE 525 Query: 327 LVSXISILHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 + I H N+ L+G C + G ++ ++ G+L + L Sbjct: 526 MEMMKMIGKHKNIINLLGACTQDGPLYVIVEYTSKGNLREYL 567
>EPHA3_CHICK (P29318) Ephrin type-A receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ETK1) (CEK4) Length = 983 Score = 36.2 bits (82), Expect = 0.043 Identities = 27/102 (26%), Positives = 43/102 (42%), Gaps = 4/102 (3%) Frame = +3 Query: 171 QIATDSFSMDNLVGEGTFGRVYXSQFN----DGXVLAVKKLDCTVIPFQSSDDFVELVSX 338 ++ + S+D +VG G FG V + +A+K L Q D F+ S Sbjct: 615 ELDASNISIDKVVGAGEFGEVCSGRLKLPSKKEISVAIKTLKAGYTEKQRRD-FLGEASI 673 Query: 339 ISILHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLLHLSD 464 + HPN+ L G + ++V ++ NGSL L D Sbjct: 674 MGQFDHPNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLRKHD 715
>CDC2H_PLAVI (Q9XZD6) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (Pvcrk2) Length = 288 Score = 36.2 bits (82), Expect = 0.043 Identities = 25/86 (29%), Positives = 40/86 (46%) Frame = +3 Query: 207 VGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHPNLNELVGYC 386 +GEGT+G VY +Q N G A+KK+ + +S + L H N+ +L Sbjct: 10 IGEGTYGVVYKAQNNYGETFALKKIRLEKEDEGIPSTAIREISILKELKHSNIVKLYDVI 69 Query: 387 MEHGXHLLVYDFHRNGSLHDLLHLSD 464 +LV++ H + L LL + D Sbjct: 70 HTKKRLILVFE-HLDQDLKKLLDVCD 94
>CDC2H_PLAKH (O96821) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 288 Score = 36.2 bits (82), Expect = 0.043 Identities = 25/86 (29%), Positives = 40/86 (46%) Frame = +3 Query: 207 VGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHPNLNELVGYC 386 +GEGT+G VY +Q N G A+KK+ + +S + L H N+ +L Sbjct: 10 IGEGTYGVVYKAQNNYGETFALKKIRLEKEDEGIPSTAIREISILKELKHSNIVKLYDVI 69 Query: 387 MEHGXHLLVYDFHRNGSLHDLLHLSD 464 +LV++ H + L LL + D Sbjct: 70 HTKKRLILVFE-HLDQDLKKLLDVCD 94
>ROR1_HUMAN (Q01973) Tyrosine-protein kinase transmembrane receptor ROR1| precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1) Length = 937 Score = 36.2 bits (82), Expect = 0.043 Identities = 23/87 (26%), Positives = 43/87 (49%), Gaps = 5/87 (5%) Frame = +3 Query: 207 VGEGTFGRVYXSQF-----NDGXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHPNLNE 371 +GE FG++Y + ++A+K L P Q +F + S ++ LHHPN+ Sbjct: 479 LGECAFGKIYKGHLYLPGMDHAQLVAIKTLKDYNNP-QQWMEFQQEASLMAELHHPNIVC 537 Query: 372 LVGYCMEHGXHLLVYDFHRNGSLHDLL 452 L+G + +++++ G LH+ L Sbjct: 538 LLGAVTQEQPVCMLFEYINQGDLHEFL 564
>CDK2_RAT (Q63699) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 36.2 bits (82), Expect = 0.043 Identities = 22/81 (27%), Positives = 40/81 (49%), Gaps = 1/81 (1%) Frame = +3 Query: 183 DSFSMDNLVGEGTFGRVYXSQFN-DGXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHP 359 ++F +GEGT+G VY ++ G V+A+KK+ + +S + L+HP Sbjct: 2 ENFQKVEKIGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHP 61 Query: 360 NLNELVGYCMEHGXHLLVYDF 422 N+ +L+ LV++F Sbjct: 62 NIVKLLDVIHTENKLYLVFEF 82
>CDK2_HUMAN (P24941) Cell division protein kinase 2 (EC 2.7.11.22) (p33 protein| kinase) Length = 298 Score = 36.2 bits (82), Expect = 0.043 Identities = 22/81 (27%), Positives = 40/81 (49%), Gaps = 1/81 (1%) Frame = +3 Query: 183 DSFSMDNLVGEGTFGRVYXSQFN-DGXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHP 359 ++F +GEGT+G VY ++ G V+A+KK+ + +S + L+HP Sbjct: 2 ENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHP 61 Query: 360 NLNELVGYCMEHGXHLLVYDF 422 N+ +L+ LV++F Sbjct: 62 NIVKLLDVIHTENKLYLVFEF 82
>CDK2_CRIGR (O55076) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 36.2 bits (82), Expect = 0.043 Identities = 22/81 (27%), Positives = 40/81 (49%), Gaps = 1/81 (1%) Frame = +3 Query: 183 DSFSMDNLVGEGTFGRVYXSQFN-DGXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHP 359 ++F +GEGT+G VY ++ G V+A+KK+ + +S + L+HP Sbjct: 2 ENFQKVEKIGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHP 61 Query: 360 NLNELVGYCMEHGXHLLVYDF 422 N+ +L+ LV++F Sbjct: 62 NIVKLLDVIHTENKLYLVFEF 82
>CDK2_BOVIN (Q5E9Y0) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 36.2 bits (82), Expect = 0.043 Identities = 22/81 (27%), Positives = 40/81 (49%), Gaps = 1/81 (1%) Frame = +3 Query: 183 DSFSMDNLVGEGTFGRVYXSQFN-DGXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHP 359 ++F +GEGT+G VY ++ G V+A+KK+ + +S + L+HP Sbjct: 2 ENFQKVEKIGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHP 61 Query: 360 NLNELVGYCMEHGXHLLVYDF 422 N+ +L+ LV++F Sbjct: 62 NIVKLLDVIHTENKLYLVFEF 82
>MARK1_MOUSE (Q8VHJ5) Serine/threonine-protein kinase MARK1 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 1) (ELKL motif serine/threonine-protein kinase 3) Length = 795 Score = 36.2 bits (82), Expect = 0.043 Identities = 27/114 (23%), Positives = 49/114 (42%), Gaps = 1/114 (0%) Frame = +3 Query: 114 AXKSNTKPXKAIVYSVADLQIATDSFSMDNLVGEGTFGRVYXSQFN-DGXVLAVKKLDCT 290 + + N + + S D Q ++ + +G+G F +V ++ G +AVK +D T Sbjct: 35 SSRQNIPRCRNSITSATDEQPHIGNYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKT 94 Query: 291 VIPFQSSDDFVELVSXISILHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 + S V + IL+HPN+ +L LV ++ G + D L Sbjct: 95 QLNPTSLQKLFREVRIMKILNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYL 148
>MARK1_HUMAN (Q9P0L2) Serine/threonine-protein kinase MARK1 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 1) Length = 795 Score = 36.2 bits (82), Expect = 0.043 Identities = 27/114 (23%), Positives = 49/114 (42%), Gaps = 1/114 (0%) Frame = +3 Query: 114 AXKSNTKPXKAIVYSVADLQIATDSFSMDNLVGEGTFGRVYXSQFN-DGXVLAVKKLDCT 290 + + N + + S D Q ++ + +G+G F +V ++ G +AVK +D T Sbjct: 35 SSRQNIPRCRNSITSATDEQPHIGNYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKT 94 Query: 291 VIPFQSSDDFVELVSXISILHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 + S V + IL+HPN+ +L LV ++ G + D L Sbjct: 95 QLNPTSLQKLFREVRIMKILNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYL 148
>LCK_MOUSE (P06240) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) Length = 508 Score = 36.2 bits (82), Expect = 0.043 Identities = 24/94 (25%), Positives = 43/94 (45%) Frame = +3 Query: 171 QIATDSFSMDNLVGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSSDDFVELVSXISIL 350 ++ ++ + +G G FG V+ +N +AVK L + S D F+ + + L Sbjct: 238 EVPRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSM---SPDAFLAEANLMKQL 294 Query: 351 HHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 HP L L + +++ ++ NGSL D L Sbjct: 295 QHPRLVRLYAVVTQEPIYIIT-EYMENGSLVDFL 327
>NTRK2_RAT (Q63604) BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB/GP95-TrkB) (Trk-B) Length = 821 Score = 35.8 bits (81), Expect = 0.056 Identities = 27/115 (23%), Positives = 54/115 (46%), Gaps = 15/115 (13%) Frame = +3 Query: 153 YSVADLQIATDSF----SMDNLV-----GEGTFGRVYXSQF------NDGXVLAVKKLDC 287 + + + Q+ D+F N+V GEG FG+V+ ++ D ++AVK L Sbjct: 516 FGITNSQLKPDTFVQHIKRHNIVLKRELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKD 575 Query: 288 TVIPFQSSDDFVELVSXISILHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 + DF ++ L H ++ + G C+E ++V+++ ++G L+ L Sbjct: 576 A--SDNARKDFHREAELLTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFL 628
>NTRK2_MOUSE (P15209) BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB/GP95-TrkB) (Trk-B) Length = 821 Score = 35.8 bits (81), Expect = 0.056 Identities = 27/115 (23%), Positives = 54/115 (46%), Gaps = 15/115 (13%) Frame = +3 Query: 153 YSVADLQIATDSF----SMDNLV-----GEGTFGRVYXSQF------NDGXVLAVKKLDC 287 + + + Q+ D+F N+V GEG FG+V+ ++ D ++AVK L Sbjct: 516 FGITNSQLKPDTFVQHIKRHNIVLKRELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKD 575 Query: 288 TVIPFQSSDDFVELVSXISILHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 + DF ++ L H ++ + G C+E ++V+++ ++G L+ L Sbjct: 576 A--SDNARKDFHREAELLTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFL 628
>ABL2_HUMAN (P42684) Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine| leukemia viral oncogene homolog 2) (Tyrosine kinase ARG) Length = 1182 Score = 35.8 bits (81), Expect = 0.056 Identities = 28/112 (25%), Positives = 52/112 (46%), Gaps = 5/112 (4%) Frame = +3 Query: 132 KPXKAIVYSVADL----QIATDSFSMDNLVGEGTFGRVYXSQFND-GXVLAVKKLDCTVI 296 K K VY V+ + ++ +M + +G G +G VY + +AVK L + Sbjct: 265 KCNKPTVYGVSPIHDKWEMERTDITMKHKLGGGQYGEVYVGVWKKYSLTVAVKTLKEDTM 324 Query: 297 PFQSSDDFVELVSXISILHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 + +F++ + + + HPNL +L+G C +V ++ G+L D L Sbjct: 325 EVE---EFLKEAAVMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYL 373
>CPK24_ARATH (Q9LDI3) CBL-interacting serine/threonine-protein kinase 24 (EC| 2.7.11.1) (SNF1-related kinase 3.11) (SALT OVERLY SENSITIVE 2 protein) Length = 446 Score = 35.8 bits (81), Expect = 0.056 Identities = 23/88 (26%), Positives = 41/88 (46%), Gaps = 2/88 (2%) Frame = +3 Query: 189 FSMDNLVGEGTFGRVYXSQFND-GXVLAVKKL-DCTVIPFQSSDDFVELVSXISILHHPN 362 + + +GEGTF +V ++ D G +A+K + T++ + D +S + I+ HPN Sbjct: 11 YEVGRTIGEGTFAKVKFARNTDTGDNVAIKIMAKSTILKNRMVDQIKREISIMKIVRHPN 70 Query: 363 LNELVGYCMEHGXHLLVYDFHRNGSLHD 446 + L +V +F G L D Sbjct: 71 IVRLYEVLASPSKIYIVLEFVTGGELFD 98
>TESK1_HUMAN (Q15569) Dual specificity testis-specific protein kinase 1 (EC| 2.7.12.1) (Testicular protein kinase 1) Length = 626 Score = 35.8 bits (81), Expect = 0.056 Identities = 23/90 (25%), Positives = 39/90 (43%) Frame = +3 Query: 183 DSFSMDNLVGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHPN 362 D F +G G F VY + + V K++ +P + E V ++ L HPN Sbjct: 55 DDFHCAEKIGAGFFSEVYKVRHRQSGQVMVLKMN--KLPSNRGNTLRE-VQLMNRLRHPN 111 Query: 363 LNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 + +G C+ G + ++ G+L LL Sbjct: 112 ILRFMGVCVHQGQLHALTEYMNGGTLEQLL 141
>CDC2_HUMAN (P06493) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 35.8 bits (81), Expect = 0.056 Identities = 21/73 (28%), Positives = 35/73 (47%), Gaps = 1/73 (1%) Frame = +3 Query: 207 VGEGTFGRVYXSQFND-GXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHPNLNELVGY 383 +GEGT+G VY + G V+A+KK+ + +S + L HPN+ L Sbjct: 10 IGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDV 69 Query: 384 CMEHGXHLLVYDF 422 M+ L+++F Sbjct: 70 LMQDSRLYLIFEF 82
>CDC2_BOVIN (P48734) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 35.8 bits (81), Expect = 0.056 Identities = 21/73 (28%), Positives = 35/73 (47%), Gaps = 1/73 (1%) Frame = +3 Query: 207 VGEGTFGRVYXSQFND-GXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHPNLNELVGY 383 +GEGT+G VY + G V+A+KK+ + +S + L HPN+ L Sbjct: 10 IGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDV 69 Query: 384 CMEHGXHLLVYDF 422 M+ L+++F Sbjct: 70 LMQDSRLYLIFEF 82
>NTRK2_CHICK (Q91987) BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (Trk-B) Length = 818 Score = 35.8 bits (81), Expect = 0.056 Identities = 27/115 (23%), Positives = 54/115 (46%), Gaps = 15/115 (13%) Frame = +3 Query: 153 YSVADLQIATDSF----SMDNLV-----GEGTFGRVYXSQF------NDGXVLAVKKLDC 287 + + + Q+ D+F N+V GEG FG+V+ ++ D ++AVK L Sbjct: 513 FGITNSQLKPDTFVQHIKRHNIVLKRELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKD 572 Query: 288 TVIPFQSSDDFVELVSXISILHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 + DF ++ L H ++ + G C+E ++V+++ ++G L+ L Sbjct: 573 A--SDNARKDFHREAELLTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFL 625
>NTRK2_HUMAN (Q16620) BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB) (Trk-B) Length = 822 Score = 35.8 bits (81), Expect = 0.056 Identities = 27/115 (23%), Positives = 54/115 (46%), Gaps = 15/115 (13%) Frame = +3 Query: 153 YSVADLQIATDSF----SMDNLV-----GEGTFGRVYXSQF------NDGXVLAVKKLDC 287 + + + Q+ D+F N+V GEG FG+V+ ++ D ++AVK L Sbjct: 517 FGITNSQLKPDTFVQHIKRHNIVLKRELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKD 576 Query: 288 TVIPFQSSDDFVELVSXISILHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 + DF ++ L H ++ + G C+E ++V+++ ++G L+ L Sbjct: 577 A--SDNARKDFHREAELLTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFL 629
>LCK_AOTNA (Q5PXS1) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) Length = 508 Score = 35.8 bits (81), Expect = 0.056 Identities = 24/94 (25%), Positives = 43/94 (45%) Frame = +3 Query: 171 QIATDSFSMDNLVGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSSDDFVELVSXISIL 350 ++ ++ + +G G FG V+ +ND +AVK L + S D F+ + + L Sbjct: 238 EVPRETLKLVERLGAGQFGEVWMGYYNDHTKVAVKSLKQGSM---SPDAFLAEANLMKQL 294 Query: 351 HHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 H L L + +++ ++ NGSL D L Sbjct: 295 QHQRLVRLYAVVTQEPIYIIT-EYMENGSLVDFL 327
>EPHB1_RAT (P09759) Ephrin type-B receptor 1 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH-2) (ELK) Length = 984 Score = 35.8 bits (81), Expect = 0.056 Identities = 25/102 (24%), Positives = 43/102 (42%), Gaps = 4/102 (3%) Frame = +3 Query: 171 QIATDSFSMDNLVGEGTFGRVYXSQFN----DGXVLAVKKLDCTVIPFQSSDDFVELVSX 338 +I ++ ++G G FG VY + +A+K L Q D F+ S Sbjct: 613 EIDVSFVKIEEVIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYSEKQRRD-FLSEASI 671 Query: 339 ISILHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLLHLSD 464 + HPN+ L G + +++ +F NG+L L +D Sbjct: 672 MGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQND 713
>EPHB1_HUMAN (P54762) Ephrin type-B receptor 1 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH-2) (NET) (HEK6) (ELK) Length = 984 Score = 35.8 bits (81), Expect = 0.056 Identities = 25/102 (24%), Positives = 43/102 (42%), Gaps = 4/102 (3%) Frame = +3 Query: 171 QIATDSFSMDNLVGEGTFGRVYXSQFN----DGXVLAVKKLDCTVIPFQSSDDFVELVSX 338 +I ++ ++G G FG VY + +A+K L Q D F+ S Sbjct: 613 EIDVSFVKIEEVIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYSEKQRRD-FLSEASI 671 Query: 339 ISILHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLLHLSD 464 + HPN+ L G + +++ +F NG+L L +D Sbjct: 672 MGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQND 713
>EPHB1_CHICK (Q07494) Ephrin type-B receptor 1 (EC 2.7.10.1) (Tyrosine-protein| kinase receptor EPH-2) (Tyrosine kinase CEK6 receptor) (Fragment) Length = 984 Score = 35.8 bits (81), Expect = 0.056 Identities = 25/102 (24%), Positives = 43/102 (42%), Gaps = 4/102 (3%) Frame = +3 Query: 171 QIATDSFSMDNLVGEGTFGRVYXSQFN----DGXVLAVKKLDCTVIPFQSSDDFVELVSX 338 +I ++ ++G G FG VY + +A+K L Q D F+ S Sbjct: 613 EIDVSFVKIEEVIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYSEKQRRD-FLSEASI 671 Query: 339 ISILHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLLHLSD 464 + HPN+ L G + +++ +F NG+L L +D Sbjct: 672 MGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQND 713
>CDC2H_PLAYO (Q7RM49) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 289 Score = 35.8 bits (81), Expect = 0.056 Identities = 29/91 (31%), Positives = 46/91 (50%), Gaps = 5/91 (5%) Frame = +3 Query: 207 VGEGTFGRVYXSQFNDGXVLAVKKL----DCTVIPFQSSDDFVELVSXISILHHPNLNEL 374 +GEGT+G VY +Q +DG A+KK+ + IP S + +S + L H N+ +L Sbjct: 10 IGEGTYGVVYKAQNSDGESFALKKIRLEKEDEGIPSTVS---IREISILKELRHSNIVKL 66 Query: 375 VGYCMEHGXHLLVYDF-HRNGSLHDLLHLSD 464 Y + H L+ F H + L L+ + D Sbjct: 67 --YDVIHAKKRLILVFEHLDQDLKKLIDVCD 95
>CAD96_DROME (Q9VBW3) Tyrosine kinase receptor Cad96Ca precursor (EC 2.7.10.1)| (Cadherin 96Ca) (Tyrosine kinase receptor HD-14) Length = 773 Score = 35.8 bits (81), Expect = 0.056 Identities = 26/93 (27%), Positives = 42/93 (45%), Gaps = 6/93 (6%) Frame = +3 Query: 201 NLVGEGTFGRVYXSQF-----NDG-XVLAVKKLDCTVIPFQSSDDFVELVSXISILHHPN 362 N++GEG FG+V+ + N+G +AVK L + D EL S+ H N Sbjct: 474 NILGEGAFGQVWRCEATNINGNEGITTVAVKTLKESATEVDRKDLLSELEVMKSLEPHIN 533 Query: 363 LNELVGYCMEHGXHLLVYDFHRNGSLHDLLHLS 461 + L+G C + ++ ++ G L L S Sbjct: 534 VVHLLGCCTDKDPTFVILEYVNRGKLQTYLRSS 566
>EPHA1_MOUSE (Q60750) Ephrin type-A receptor 1 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ESK) Length = 977 Score = 35.4 bits (80), Expect = 0.073 Identities = 22/95 (23%), Positives = 41/95 (43%), Gaps = 9/95 (9%) Frame = +3 Query: 195 MDNLVGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSSDD---------FVELVSXISI 347 +D ++GEG FG VY L + DC + ++ D F+ + + Sbjct: 627 VDTVIGEGEFGEVYRG------ALRLPSQDCKTVAIKTLKDTSPDGYWWNFLREATIMGQ 680 Query: 348 LHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 +HP++ L G + +++ +F NG+L L Sbjct: 681 FNHPHILRLEGVITKRKPIMIITEFMENGALDAFL 715
>YRK_CHICK (Q02977) Proto-oncogene tyrosine-protein kinase Yrk (EC 2.7.10.2)| (p60-Yrk) (Yes-related kinase) Length = 535 Score = 35.4 bits (80), Expect = 0.073 Identities = 28/98 (28%), Positives = 43/98 (43%) Frame = +3 Query: 171 QIATDSFSMDNLVGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSSDDFVELVSXISIL 350 +I +S + +G G FG V+ +N +AVK L + S + F+E + L Sbjct: 263 EIPRESLQLLQKLGNGQFGEVWMGTWNGTTKVAVKTLKPGTM---SPEAFLEEAQIMKRL 319 Query: 351 HHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLLHLSD 464 H L +L E + +V +F GSL D L D Sbjct: 320 RHDKLVQLYAVVSEEPIY-IVTEFMSQGSLLDFLKDGD 356
>ROS_CHICK (P08941) Proto-oncogene tyrosine-protein kinase ROS precursor (EC| 2.7.10.1) (c-ros-1) Length = 2311 Score = 35.4 bits (80), Expect = 0.073 Identities = 28/112 (25%), Positives = 48/112 (42%), Gaps = 7/112 (6%) Frame = +3 Query: 126 NTKPXKAIVYSVADLQIATDSFSMDNLVGEGTFGRVYXSQFNDGXV-------LAVKKLD 284 +T P +A + S+ D ++ L+G G FG VY D +AVK L Sbjct: 1942 STLPSQAEIESLP--AFPRDKLNLHKLLGSGAFGEVYEGTALDILADGSGESRVAVKTLK 1999 Query: 285 CTVIPFQSSDDFVELVSXISILHHPNLNELVGYCMEHGXHLLVYDFHRNGSL 440 Q +F++ +S HP++ +L+G C+ + L+ + G L Sbjct: 2000 RGATD-QEKSEFLKEAHLMSKFDHPHILKLLGVCLLNEPQYLILELMEGGDL 2050
>EPB1A_XENLA (Q91571) Ephrin type-B receptor 1-A precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor XEK) Length = 985 Score = 35.4 bits (80), Expect = 0.073 Identities = 25/102 (24%), Positives = 43/102 (42%), Gaps = 4/102 (3%) Frame = +3 Query: 171 QIATDSFSMDNLVGEGTFGRVYXSQFN----DGXVLAVKKLDCTVIPFQSSDDFVELVSX 338 +I ++ ++G G FG VY + +A+K L Q D F+ S Sbjct: 614 EIDVSFVKIEEVIGAGEFGEVYKGRLKLPSKREISVAIKTLKAGYSEKQRRD-FLSEASI 672 Query: 339 ISILHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLLHLSD 464 + HPN+ L G + +++ +F NG+L L +D Sbjct: 673 MGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQND 714
>ROS_AVISU (P00529) Tyrosine-protein kinase transforming protein ros (EC| 2.7.10.1) Length = 402 Score = 35.4 bits (80), Expect = 0.073 Identities = 28/112 (25%), Positives = 48/112 (42%), Gaps = 7/112 (6%) Frame = +3 Query: 126 NTKPXKAIVYSVADLQIATDSFSMDNLVGEGTFGRVYXSQFNDGXV-------LAVKKLD 284 +T P +A + S+ D ++ L+G G FG VY D +AVK L Sbjct: 79 STLPSQAEIESLP--AFPRDKLNLHKLLGSGAFGEVYEGTALDILADGSGESRVAVKTLK 136 Query: 285 CTVIPFQSSDDFVELVSXISILHHPNLNELVGYCMEHGXHLLVYDFHRNGSL 440 Q +F++ +S HP++ +L+G C+ + L+ + G L Sbjct: 137 RGATD-QEKSEFLKEAHLMSKFDHPHILKLLGVCLLNEPQYLILELMEGGDL 187
>M3K2_ARATH (Q9FZ36) Mitogen-activated protein kinase kinase kinase 2 (EC| 2.7.11.25) (Arabidospsis NPK1-related protein kinase 2) Length = 651 Score = 35.4 bits (80), Expect = 0.073 Identities = 27/93 (29%), Positives = 44/93 (47%), Gaps = 10/93 (10%) Frame = +3 Query: 204 LVGEGTFGRVYXSQ-FNDGXVLAVKKL---------DCTVIPFQSSDDFVELVSXISILH 353 L+G G FG VY + G +LAVK++ + T Q ++ V+L+ +S Sbjct: 73 LIGRGAFGTVYMGMNLDSGELLAVKQVLITSNCASKEKTQAHIQELEEEVKLLKNLS--- 129 Query: 354 HPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 HPN+ +G E ++ +F GS+ LL Sbjct: 130 HPNIVRYLGTVREDETLNILLEFVPGGSISSLL 162
>PLK4_MOUSE (Q64702) Serine/threonine-protein kinase PLK4 (EC 2.7.11.21)| (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase Sak) (Serine/threonine-protein kinase 18) Length = 925 Score = 35.4 bits (80), Expect = 0.073 Identities = 25/92 (27%), Positives = 45/92 (48%), Gaps = 2/92 (2%) Frame = +3 Query: 183 DSFSMDNLVGEGTFGRVYXSQ-FNDGXVLAVKKLDCTVIPFQSSDDFVELVSXISI-LHH 356 + F + NL+G+G+F VY ++ + G +A+K +D + V+ I L H Sbjct: 10 EDFKVGNLLGKGSFAGVYRAESIHTGLEVAIKMIDKKAMYKAGMVQRVQNEVKIHCQLKH 69 Query: 357 PNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 P++ EL Y ++ LV + NG ++ L Sbjct: 70 PSVLELYNYFEDNNYVYLVLEMCHNGEMNRYL 101
>MARK2_MOUSE (Q05512) Serine/threonine-protein kinase MARK2 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 2) (ELKL Motif Kinase) (EMK1) Length = 776 Score = 35.4 bits (80), Expect = 0.073 Identities = 34/135 (25%), Positives = 56/135 (41%), Gaps = 1/135 (0%) Frame = +3 Query: 51 PAKIERNKXXXXXXXXXXKPVAXKSNTKPXKAIVYSVADLQIATDSFSMDNLVGEGTFGR 230 P ER+ KP + KSN + S AD Q ++ + +G+G F + Sbjct: 9 PTLNERDTEQPTLGHLDSKP-SSKSNMLRGRNSATS-ADEQPHIGNYRLLKTIGKGNFAK 66 Query: 231 VYXSQ-FNDGXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHPNLNELVGYCMEHGXHL 407 V ++ G +AVK +D T + S V + +L+HPN+ +L Sbjct: 67 VKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNIVKLFEVIETEKTLY 126 Query: 408 LVYDFHRNGSLHDLL 452 LV ++ G + D L Sbjct: 127 LVMEYASGGEVFDYL 141
>CDC2_RAT (P39951) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 35.4 bits (80), Expect = 0.073 Identities = 20/73 (27%), Positives = 35/73 (47%), Gaps = 1/73 (1%) Frame = +3 Query: 207 VGEGTFGRVYXSQFND-GXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHPNLNELVGY 383 +GEGT+G VY + G ++A+KK+ + +S + L HPN+ L Sbjct: 10 IGEGTYGVVYKGRHRTTGQIVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDV 69 Query: 384 CMEHGXHLLVYDF 422 M+ L+++F Sbjct: 70 LMQDSRLYLIFEF 82
>CDC2_MOUSE (P11440) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 35.4 bits (80), Expect = 0.073 Identities = 20/73 (27%), Positives = 35/73 (47%), Gaps = 1/73 (1%) Frame = +3 Query: 207 VGEGTFGRVYXSQFN-DGXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHPNLNELVGY 383 +GEGT+G VY + G ++A+KK+ + +S + L HPN+ L Sbjct: 10 IGEGTYGVVYKGRHRVTGQIVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDV 69 Query: 384 CMEHGXHLLVYDF 422 M+ L+++F Sbjct: 70 LMQDSRLYLIFEF 82
>RET_HUMAN (P07949) Proto-oncogene tyrosine-protein kinase receptor ret| precursor (EC 2.7.10.1) (C-ret) Length = 1114 Score = 35.4 bits (80), Expect = 0.073 Identities = 27/91 (29%), Positives = 45/91 (49%), Gaps = 6/91 (6%) Frame = +3 Query: 207 VGEGTFGRVY-XSQFN-----DGXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHPNLN 368 +GEG FG+V + F+ +AVK L P + D E + + ++HP++ Sbjct: 730 LGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEF-NVLKQVNHPHVI 788 Query: 369 ELVGYCMEHGXHLLVYDFHRNGSLHDLLHLS 461 +L G C + G LL+ ++ + GSL L S Sbjct: 789 KLYGACSQDGPLLLIVEYAKYGSLRGFLRES 819
>MARK2_RAT (O08679) Serine/threonine-protein kinase MARK2 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 2) (ELKL Motif Kinase) (EMK1) Length = 722 Score = 35.4 bits (80), Expect = 0.073 Identities = 34/135 (25%), Positives = 56/135 (41%), Gaps = 1/135 (0%) Frame = +3 Query: 51 PAKIERNKXXXXXXXXXXKPVAXKSNTKPXKAIVYSVADLQIATDSFSMDNLVGEGTFGR 230 P ER+ KP + KSN + S AD Q ++ + +G+G F + Sbjct: 9 PTLNERDTEQPTLGHLDSKP-SSKSNMLRGRNSATS-ADEQPHIGNYRLLKTIGKGNFAK 66 Query: 231 VYXSQ-FNDGXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHPNLNELVGYCMEHGXHL 407 V ++ G +AVK +D T + S V + +L+HPN+ +L Sbjct: 67 VKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNIVKLFEVIETEKTLY 126 Query: 408 LVYDFHRNGSLHDLL 452 LV ++ G + D L Sbjct: 127 LVMEYASGGEVFDYL 141
>EPHA3_HUMAN (P29320) Ephrin type-A receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ETK1) (HEK) (HEK4) Length = 983 Score = 35.4 bits (80), Expect = 0.073 Identities = 27/102 (26%), Positives = 43/102 (42%), Gaps = 4/102 (3%) Frame = +3 Query: 171 QIATDSFSMDNLVGEGTFGRVYXSQFN----DGXVLAVKKLDCTVIPFQSSDDFVELVSX 338 ++ + S+D +VG G FG V + +A+K L Q D F+ S Sbjct: 615 ELDATNISIDKVVGAGEFGEVCSGRLKLPSKKEISVAIKTLKVGYTEKQRRD-FLGEASI 673 Query: 339 ISILHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLLHLSD 464 + HPN+ L G + ++V ++ NGSL L D Sbjct: 674 MGQFDHPNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLRKHD 715
>TAOK2_XENLA (Q6GPK9) Serine/threonine-protein kinase TAO2 (EC 2.7.11.1)| (Thousand and one amino acid protein 2) Length = 1025 Score = 35.4 bits (80), Expect = 0.073 Identities = 29/89 (32%), Positives = 47/89 (52%), Gaps = 5/89 (5%) Frame = +3 Query: 207 VGEGTFGRVYXSQ-FNDGXVLAVKKLDCTVIPFQSSD---DFVELVSXISILHHPNLNEL 374 +G G+FG VY ++ + V+A+KK+ + QS++ D ++ V + L HPN E Sbjct: 34 IGHGSFGAVYFARDIRNNEVVAIKKMSYS--GKQSNEKWQDIIKEVKFLQKLRHPNTIEY 91 Query: 375 VG-YCMEHGXHLLVYDFHRNGSLHDLLHL 458 G Y EH L++ + GS DLL + Sbjct: 92 KGCYLREHTAWLVME--YCLGSASDLLEV 118
>EPB1B_XENLA (Q91736) Ephrin type-B receptor 1-B (EC 2.7.10.1) (Tyrosine-protein| kinase receptor XELK) (Fragment) Length = 902 Score = 35.4 bits (80), Expect = 0.073 Identities = 25/102 (24%), Positives = 43/102 (42%), Gaps = 4/102 (3%) Frame = +3 Query: 171 QIATDSFSMDNLVGEGTFGRVYXSQFN----DGXVLAVKKLDCTVIPFQSSDDFVELVSX 338 +I ++ ++G G FG VY + +A+K L Q D F+ S Sbjct: 531 EIDVSFVKIEEVIGAGEFGEVYKGRLKLPSKREISVAIKTLKAGYSEKQRRD-FLSEASI 589 Query: 339 ISILHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLLHLSD 464 + HPN+ L G + +++ +F NG+L L +D Sbjct: 590 MGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQND 631
>CDK3_HUMAN (Q00526) Cell division protein kinase 3 (EC 2.7.11.22)| Length = 305 Score = 35.4 bits (80), Expect = 0.073 Identities = 22/81 (27%), Positives = 39/81 (48%), Gaps = 1/81 (1%) Frame = +3 Query: 183 DSFSMDNLVGEGTFGRVYXSQFND-GXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHP 359 D F +GEGT+G VY ++ + G ++A+KK+ + + +S + L HP Sbjct: 2 DMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKHP 61 Query: 360 NLNELVGYCMEHGXHLLVYDF 422 N+ L+ LV++F Sbjct: 62 NIVRLLDVVHNERKLYLVFEF 82
>LCK_SAISC (Q95KR7) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) Length = 508 Score = 35.4 bits (80), Expect = 0.073 Identities = 24/94 (25%), Positives = 43/94 (45%) Frame = +3 Query: 171 QIATDSFSMDNLVGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSSDDFVELVSXISIL 350 ++ ++ + +G G FG V+ +N+ +AVK L + S D F+ + + L Sbjct: 238 EVPRETLKLVERLGAGQFGEVWMGYYNEHTKVAVKSLKQGSM---SPDAFLAEANLMKQL 294 Query: 351 HHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 H L L E +++ ++ NGSL D L Sbjct: 295 QHKRLVRLYAVVTEEPIYIIT-EYMENGSLVDFL 327
>FYN_HUMAN (P06241) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) (Protooncogene Syn) (SLK) Length = 536 Score = 35.4 bits (80), Expect = 0.073 Identities = 25/94 (26%), Positives = 42/94 (44%) Frame = +3 Query: 171 QIATDSFSMDNLVGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSSDDFVELVSXISIL 350 +I +S + +G G FG V+ +N +A+K L + S + F+E + L Sbjct: 264 EIPRESLQLIKRLGNGQFGEVWMGTWNGNTKVAIKTLKPGTM---SPESFLEEAQIMKKL 320 Query: 351 HHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 H L +L E + +V ++ GSL D L Sbjct: 321 KHDKLVQLYAVVSEEPIY-IVTEYMNKGSLLDFL 353
>PLK4_HUMAN (O00444) Serine/threonine-protein kinase PLK4 (EC 2.7.11.21)| (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase Sak) (Serine/threonine-protein kinase 18) Length = 970 Score = 35.0 bits (79), Expect = 0.095 Identities = 25/92 (27%), Positives = 44/92 (47%), Gaps = 2/92 (2%) Frame = +3 Query: 183 DSFSMDNLVGEGTFGRVYXSQ-FNDGXVLAVKKLDCTVIPFQSSDDFVELVSXISI-LHH 356 + F + NL+G+G+F VY ++ + G +A+K +D + V+ I L H Sbjct: 10 EDFKVGNLLGKGSFAGVYRAESIHTGLEVAIKMIDKKAMYKAGMVQRVQNEVKIHCQLKH 69 Query: 357 PNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 P++ EL Y + LV + NG ++ L Sbjct: 70 PSILELYNYFEDSNYVYLVLEMCHNGEMNRYL 101
>PGFRB_MOUSE (P05622) Beta platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-beta) Length = 1098 Score = 35.0 bits (79), Expect = 0.095 Identities = 30/105 (28%), Positives = 47/105 (44%), Gaps = 10/105 (9%) Frame = +3 Query: 171 QIATDSFSMDNLVGEGTFGRVYX------SQFNDGXVLAVKKLDCTVIPFQSSDDFVELV 332 ++ D + +G G FG+V S +AVK L T S + L+ Sbjct: 593 ELPRDQLVLGRTLGSGAFGQVVEATAHGLSHSQATMKVAVKMLKSTA----RSSEKQALM 648 Query: 333 SXISILHH--PNLN--ELVGYCMEHGXHLLVYDFHRNGSLHDLLH 455 S + I+ H P+LN L+G C + G ++ ++ R G L D LH Sbjct: 649 SELKIMSHLGPHLNVVNLLGACTKGGPIYIITEYCRYGDLVDYLH 693
>PGFRB_HUMAN (P09619) Beta platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-beta) (CD140b antigen) Length = 1106 Score = 35.0 bits (79), Expect = 0.095 Identities = 30/105 (28%), Positives = 47/105 (44%), Gaps = 10/105 (9%) Frame = +3 Query: 171 QIATDSFSMDNLVGEGTFGRVYX------SQFNDGXVLAVKKLDCTVIPFQSSDDFVELV 332 ++ D + +G G FG+V S +AVK L T S + L+ Sbjct: 594 ELPRDQLVLGRTLGSGAFGQVVEATAHGLSHSQATMKVAVKMLKSTA----RSSEKQALM 649 Query: 333 SXISILHH--PNLN--ELVGYCMEHGXHLLVYDFHRNGSLHDLLH 455 S + I+ H P+LN L+G C + G ++ ++ R G L D LH Sbjct: 650 SELKIMSHLGPHLNVVNLLGACTKGGPIYIITEYCRYGDLVDYLH 694
>YES_CANFA (Q28923) Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2)| (p61-Yes) (c-Yes) Length = 538 Score = 35.0 bits (79), Expect = 0.095 Identities = 27/99 (27%), Positives = 46/99 (46%), Gaps = 1/99 (1%) Frame = +3 Query: 171 QIATDSFSMDNLVGEGTFGRVYXSQFNDGXVLAVKKLDC-TVIPFQSSDDFVELVSXISI 347 +I +S ++ +G+G FG V+ +N +A+K L T++P + F++ + Sbjct: 266 EIPRESLRLEVKLGQGCFGEVWMGTWNGTTKVAIKTLKLGTMMP----EAFLQEAQIMKK 321 Query: 348 LHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLLHLSD 464 L H L L E + +V +F GSL D L D Sbjct: 322 LRHDKLVPLYAVVSEEPIY-IVTEFMSKGSLLDFLKEGD 359
>PGFRB_CANFA (Q6QNF3) Beta platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-beta) Length = 1103 Score = 35.0 bits (79), Expect = 0.095 Identities = 30/105 (28%), Positives = 47/105 (44%), Gaps = 10/105 (9%) Frame = +3 Query: 171 QIATDSFSMDNLVGEGTFGRVYX------SQFNDGXVLAVKKLDCTVIPFQSSDDFVELV 332 ++ D + +G G FG+V S +AVK L T S + L+ Sbjct: 594 ELPRDQLVLGRTLGSGAFGQVVEATAHGLSHSQATMKVAVKMLKSTA----RSSEKQALM 649 Query: 333 SXISILHH--PNLN--ELVGYCMEHGXHLLVYDFHRNGSLHDLLH 455 S + I+ H P+LN L+G C + G ++ ++ R G L D LH Sbjct: 650 SELKIMSHLGPHLNVVNLLGACTKGGPIYIITEYCRYGDLVDYLH 694
>MARK3_HUMAN (P27448) MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1)| (Cdc25C-associated protein kinase 1) (cTAK1) (C-TAK1) (Serine/threonine protein kinase p78) (Ser/Thr protein kinase PAR-1) (Protein kinase STK10) Length = 776 Score = 35.0 bits (79), Expect = 0.095 Identities = 25/102 (24%), Positives = 46/102 (45%), Gaps = 1/102 (0%) Frame = +3 Query: 150 VYSVADLQIATDSFSMDNLVGEGTFGRVYXSQ-FNDGXVLAVKKLDCTVIPFQSSDDFVE 326 + S AD Q ++ + +G+G F +V ++ G +A+K +D T + S Sbjct: 43 IASCADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFR 102 Query: 327 LVSXISILHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 V + IL+HPN+ +L L+ ++ G + D L Sbjct: 103 EVRIMKILNHPNIVKLFEVIETEKTLYLIMEYASGGEVFDYL 144
>FGFR2_DROME (Q09147) Fibroblast growth factor receptor homolog 2 precursor (EC| 2.7.10.1) (Protein breathless) (dFGF-R1) Length = 1052 Score = 35.0 bits (79), Expect = 0.095 Identities = 26/106 (24%), Positives = 48/106 (45%), Gaps = 12/106 (11%) Frame = +3 Query: 171 QIATDSFSMDNLVGEGTFGRVYXSQFND--------GXVLAVKKLDCTVIPFQSSDDFVE 326 +I S+ +++GEG FGRV ++ ++AVK V + D Sbjct: 706 EIPRQQLSLGSILGEGAFGRVVMAEAEGLPRSPQLAETIVAVK----MVKEEHTDTDMAS 761 Query: 327 LVSXISIL----HHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 LV + ++ H N+ L+G C + G ++ ++ +G+L D L Sbjct: 762 LVREMEVMKMIGKHINIINLLGCCSQGGPLWVIVEYAPHGNLKDFL 807
>MARK3_MOUSE (Q03141) MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1)| (MPK-10) (ELKL motif kinase 2) Length = 753 Score = 35.0 bits (79), Expect = 0.095 Identities = 25/102 (24%), Positives = 46/102 (45%), Gaps = 1/102 (0%) Frame = +3 Query: 150 VYSVADLQIATDSFSMDNLVGEGTFGRVYXSQ-FNDGXVLAVKKLDCTVIPFQSSDDFVE 326 + S AD Q ++ + +G+G F +V ++ G +A+K +D T + S Sbjct: 43 IASCADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFR 102 Query: 327 LVSXISILHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 V + IL+HPN+ +L L+ ++ G + D L Sbjct: 103 EVRIMKILNHPNIVKLFEVIETEKTLYLIMEYASGGEVFDYL 144
>KIN28_YEAST (P06242) Serine/threonine-protein kinase KIN28 (EC 2.7.11.23)| Length = 306 Score = 35.0 bits (79), Expect = 0.095 Identities = 21/79 (26%), Positives = 38/79 (48%), Gaps = 1/79 (1%) Frame = +3 Query: 189 FSMDNLVGEGTFGRVYXS-QFNDGXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHPNL 365 ++ + VGEGT+ VY Q + G +A+K++ + + V + + HPN+ Sbjct: 7 YTKEKKVGEGTYAVVYLGCQHSTGRKIAIKEIKTSEFKDGLDMSAIREVKYLQEMQHPNV 66 Query: 366 NELVGYCMEHGXHLLVYDF 422 EL+ M + LV +F Sbjct: 67 IELIDIFMAYDNLNLVLEF 85
>CDC2_RANDY (Q9W739) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) Length = 302 Score = 35.0 bits (79), Expect = 0.095 Identities = 21/81 (25%), Positives = 38/81 (46%), Gaps = 1/81 (1%) Frame = +3 Query: 183 DSFSMDNLVGEGTFGRVYXSQFN-DGXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHP 359 D ++ +GEGT+G VY G ++A+KK+ + +S + L HP Sbjct: 2 DEYAKIEKIGEGTYGVVYKGVHKATGQIVAMKKIRLENEEEGVPSTAIREISLLKELQHP 61 Query: 360 NLNELVGYCMEHGXHLLVYDF 422 N+ L+ M+ L+++F Sbjct: 62 NIVCLLDVLMQDSRLYLIFEF 82
>MARK3_RAT (Q8VHF0) MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1)| Length = 797 Score = 35.0 bits (79), Expect = 0.095 Identities = 25/102 (24%), Positives = 46/102 (45%), Gaps = 1/102 (0%) Frame = +3 Query: 150 VYSVADLQIATDSFSMDNLVGEGTFGRVYXSQ-FNDGXVLAVKKLDCTVIPFQSSDDFVE 326 + S AD Q ++ + +G+G F +V ++ G +A+K +D T + S Sbjct: 43 IASCADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFR 102 Query: 327 LVSXISILHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 V + IL+HPN+ +L L+ ++ G + D L Sbjct: 103 EVRIMKILNHPNIVKLFEVIETEKTLYLIMEYASGGEVFDYL 144
>MARK2_HUMAN (Q7KZI7) Serine/threonine-protein kinase MARK2 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 2) (ELKL motif kinase) (EMK1) (PAR1 homolog) Length = 788 Score = 35.0 bits (79), Expect = 0.095 Identities = 25/98 (25%), Positives = 44/98 (44%), Gaps = 1/98 (1%) Frame = +3 Query: 162 ADLQIATDSFSMDNLVGEGTFGRVYXSQ-FNDGXVLAVKKLDCTVIPFQSSDDFVELVSX 338 AD Q ++ + +G+G F +V ++ G +AVK +D T + S V Sbjct: 44 ADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRI 103 Query: 339 ISILHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 + +L+HPN+ +L LV ++ G + D L Sbjct: 104 MKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYL 141
>SRC2_XENLA (P13116) Tyrosine-protein kinase Src-2 (EC 2.7.10.2) (p60-Src-2)| Length = 531 Score = 35.0 bits (79), Expect = 0.095 Identities = 25/94 (26%), Positives = 44/94 (46%) Frame = +3 Query: 171 QIATDSFSMDNLVGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSSDDFVELVSXISIL 350 +I DS ++ +G+G FG V+ +N +A+K L + S + F++ + L Sbjct: 259 EIPRDSLRLELKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTM---SPEAFLQEAQVMKKL 315 Query: 351 HHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 H L +L E + +V ++ GSL D L Sbjct: 316 RHEKLVQLYAVVSEEPIY-IVTEYMSKGSLLDFL 348
>PGFRB_RAT (Q05030) Beta platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-beta) Length = 1097 Score = 35.0 bits (79), Expect = 0.095 Identities = 30/105 (28%), Positives = 47/105 (44%), Gaps = 10/105 (9%) Frame = +3 Query: 171 QIATDSFSMDNLVGEGTFGRVYX------SQFNDGXVLAVKKLDCTVIPFQSSDDFVELV 332 ++ D + +G G FG+V S +AVK L T S + L+ Sbjct: 593 ELPRDQLVLGRTLGSGAFGQVVEATAHGLSHSQATMKVAVKMLKSTA----RSSEKQALM 648 Query: 333 SXISILHH--PNLN--ELVGYCMEHGXHLLVYDFHRNGSLHDLLH 455 S + I+ H P+LN L+G C + G ++ ++ R G L D LH Sbjct: 649 SELKIMSHLGPHLNVVNLLGACTKGGPIYIITEYCRYGDLVDYLH 693
>FYN_XIPHE (P27446) Proto-oncogene tyrosine-protein kinase FYN (EC 2.7.10.2)| (P59-FYN) Length = 536 Score = 35.0 bits (79), Expect = 0.095 Identities = 26/94 (27%), Positives = 42/94 (44%) Frame = +3 Query: 171 QIATDSFSMDNLVGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSSDDFVELVSXISIL 350 +I +S + +G G FG V+ +N +AVK L + S + F+E + L Sbjct: 264 EIPRESLQLIKRLGNGQFGEVWMGTWNGTTKVAVKTLKPGTM---SPESFLEEAQIMKKL 320 Query: 351 HHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 H L +L E + +V ++ GSL D L Sbjct: 321 RHDKLVQLYAVVSEEPIY-IVTEYMSKGSLLDFL 353
>FYN_XENLA (P13406) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 536 Score = 35.0 bits (79), Expect = 0.095 Identities = 25/94 (26%), Positives = 42/94 (44%) Frame = +3 Query: 171 QIATDSFSMDNLVGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSSDDFVELVSXISIL 350 +I +S + +G G FG V+ +N +A+K L + S + F+E + L Sbjct: 264 EIPRESLQLIKRLGNGQFGEVWMGTWNGNTKVAIKTLKPGTM---SPESFLEEAQIMKKL 320 Query: 351 HHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 H L +L E + +V ++ GSL D L Sbjct: 321 KHDKLVQLYAVVSEEPIY-IVTEYMSKGSLLDFL 353
>NTRK3_RAT (Q03351) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (GP145-TrkC) (Trk-C) Length = 864 Score = 34.7 bits (78), Expect = 0.12 Identities = 21/88 (23%), Positives = 44/88 (50%), Gaps = 6/88 (6%) Frame = +3 Query: 207 VGEGTFGRVYXSQF------NDGXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHPNLN 368 +GEG FG+V+ ++ D ++AVK L + + DF ++ L H ++ Sbjct: 544 LGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPTLAARK--DFQREAELLTNLQHEHIV 601 Query: 369 ELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 + G C + ++V+++ ++G L+ L Sbjct: 602 KFYGVCGDGDPLIMVFEYMKHGDLNKFL 629
>SRC_RSVH1 (P25020) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 34.7 bits (78), Expect = 0.12 Identities = 23/94 (24%), Positives = 45/94 (47%) Frame = +3 Query: 171 QIATDSFSMDNLVGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSSDDFVELVSXISIL 350 +I +S ++ +G+G FG V+ +N +A+K L + S + F++ + L Sbjct: 260 EIPRESLRLEAKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTM---SPEAFLQEAQVMKKL 316 Query: 351 HHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 H L +L E ++++ ++ GSL D L Sbjct: 317 RHEKLVQLYAVVSEEPIYIVI-EYMSKGSLLDFL 349
>RYK2_DROME (Q9V422) Tyrosine-protein kinase Dnt precursor (EC 2.7.10.1)| (Protein doughnut) Length = 584 Score = 34.7 bits (78), Expect = 0.12 Identities = 25/90 (27%), Positives = 44/90 (48%), Gaps = 4/90 (4%) Frame = +3 Query: 159 VADLQIATDSFSMDNLVGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSSDDFVELVSX 338 +++L + + +L+ EGTFGRVY +ND + VK TV S + L+ Sbjct: 307 ISELTVERCRVRLSSLLQEGTFGRVYRGTYNDTQDVLVK----TVAQHASQMQVLLLLQE 362 Query: 339 ISILH---HPNLNELVGYCME-HGXHLLVY 416 +L+ HP + ++G +E H ++Y Sbjct: 363 GMLLYGASHPGILSVLGVSIEDHTTPFVLY 392
>EPHB3_XENLA (Q91735) Ephrin type-B receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor TCK) Length = 974 Score = 34.7 bits (78), Expect = 0.12 Identities = 24/102 (23%), Positives = 42/102 (41%), Gaps = 4/102 (3%) Frame = +3 Query: 171 QIATDSFSMDNLVGEGTFGRVYXSQFNDGX----VLAVKKLDCTVIPFQSSDDFVELVSX 338 +I ++ ++G G FG V + +A+K L Q DF+ S Sbjct: 603 EIDISCVKIEEVIGAGEFGEVCRGKLKQAGRREQFVAIKTLKAGYTE-QQRRDFLGEASI 661 Query: 339 ISILHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLLHLSD 464 + HPN+ L G +++ +F NG+L L ++D Sbjct: 662 MGQFDHPNIIRLEGVVTRSRPVMILTEFMENGALDSFLRMND 703
>EPHA1_HUMAN (P21709) Ephrin type-A receptor 1 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH) Length = 976 Score = 34.7 bits (78), Expect = 0.12 Identities = 24/90 (26%), Positives = 41/90 (45%), Gaps = 4/90 (4%) Frame = +3 Query: 195 MDNLVGEGTFGRVYXSQF----NDGXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHPN 362 +D ++GEG FG VY D +A+K L T P +F+ + + HP+ Sbjct: 626 VDTVIGEGEFGEVYRGTLRLPSQDCKTVAIKTLKDT-SPGGQWWNFLREATIMGQFSHPH 684 Query: 363 LNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 + L G + +++ +F NG+L L Sbjct: 685 ILHLEGVVTKRKPIMIITEFMENGALDAFL 714
>DDR1_PANTR (Q7YR43) Epithelial discoidin domain-containing receptor 1| precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (CD167a antigen) Length = 909 Score = 34.7 bits (78), Expect = 0.12 Identities = 27/101 (26%), Positives = 46/101 (45%), Gaps = 19/101 (18%) Frame = +3 Query: 207 VGEGTFGRVYXSQFNDGX-----------------VLAVKKL--DCTVIPFQSSDDFVEL 329 +GEG FG V+ + + ++AVK L D T + +DF++ Sbjct: 612 LGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATK---NARNDFLKE 668 Query: 330 VSXISILHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 V +S L PN+ L+G C++ ++ D+ NG L+ L Sbjct: 669 VKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFL 709
>DDR1_HUMAN (Q08345) Epithelial discoidin domain-containing receptor 1| precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (TRK E) Length = 913 Score = 34.7 bits (78), Expect = 0.12 Identities = 27/101 (26%), Positives = 46/101 (45%), Gaps = 19/101 (18%) Frame = +3 Query: 207 VGEGTFGRVYXSQFNDGX-----------------VLAVKKL--DCTVIPFQSSDDFVEL 329 +GEG FG V+ + + ++AVK L D T + +DF++ Sbjct: 616 LGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATK---NARNDFLKE 672 Query: 330 VSXISILHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 V +S L PN+ L+G C++ ++ D+ NG L+ L Sbjct: 673 VKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFL 713
>FGFR4_HUMAN (P22455) Fibroblast growth factor receptor 4 precursor (EC| 2.7.10.1) (FGFR-4) (CD334 antigen) Length = 802 Score = 34.7 bits (78), Expect = 0.12 Identities = 31/123 (25%), Positives = 52/123 (42%), Gaps = 20/123 (16%) Frame = +3 Query: 144 AIVYSVADLQIATD---SFSMDNLV-----GEGTFGRVYXSQF--------NDGXVLAVK 275 A++ + L + D F D LV GEG FG+V ++ + +AVK Sbjct: 444 ALLAGLVSLDLPLDPLWEFPRDRLVLGKPLGEGCFGQVVRAEAFGMDPARPDQASTVAVK 503 Query: 276 KLDCTVIPFQSSDDFVELVSXISIL----HHPNLNELVGYCMEHGXHLLVYDFHRNGSLH 443 L S D +LVS + ++ H N+ L+G C + G ++ + G+L Sbjct: 504 MLKDNA----SDKDLADLVSEMEVMKLIGRHKNIINLLGVCTQEGPLYVIVECAAKGNLR 559 Query: 444 DLL 452 + L Sbjct: 560 EFL 562
>CEK2_CHICK (P18460) Tyrosine kinase receptor CEK2 precursor (EC 2.7.10.1)| Length = 806 Score = 34.7 bits (78), Expect = 0.12 Identities = 25/102 (24%), Positives = 44/102 (43%), Gaps = 8/102 (7%) Frame = +3 Query: 171 QIATDSFSMDNLVGEGTFGRVYXSQF--------NDGXVLAVKKLDCTVIPFQSSDDFVE 326 ++A ++ +GEG FG+V ++ N +AVK L SD E Sbjct: 460 ELARSRLTLGKPLGEGCFGQVVMAEAIGIDKDKPNKAITVAVKMLKDDATDKDLSDLVSE 519 Query: 327 LVSXISILHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 + I H N+ L+G C + G ++ ++ G+L + L Sbjct: 520 MEMMKMIGKHKNIINLLGACTQDGPLYVLVEYASKGNLREYL 561
>CDC2H_PLAFK (Q07785) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (PfPK5) Length = 288 Score = 34.7 bits (78), Expect = 0.12 Identities = 27/87 (31%), Positives = 41/87 (47%), Gaps = 1/87 (1%) Frame = +3 Query: 207 VGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHPNLNELVGYC 386 +GEGT+G VY +Q N G A+KK+ + +S + L H N+ +L Y Sbjct: 10 IGEGTYGVVYKAQNNYGETFALKKIRLEKEDEGIPSTTIREISILKELKHSNIVKL--YD 67 Query: 387 MEHGXHLLVYDF-HRNGSLHDLLHLSD 464 + H LV F H + L LL + + Sbjct: 68 VIHTKKRLVLVFEHLDQDLKKLLDVCE 94
>CDC2H_PLAF7 (P61075) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 288 Score = 34.7 bits (78), Expect = 0.12 Identities = 27/87 (31%), Positives = 41/87 (47%), Gaps = 1/87 (1%) Frame = +3 Query: 207 VGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHPNLNELVGYC 386 +GEGT+G VY +Q N G A+KK+ + +S + L H N+ +L Y Sbjct: 10 IGEGTYGVVYKAQNNYGETFALKKIRLEKEDEGIPSTTIREISILKELKHSNIVKL--YD 67 Query: 387 MEHGXHLLVYDF-HRNGSLHDLLHLSD 464 + H LV F H + L LL + + Sbjct: 68 VIHTKKRLVLVFEHLDQDLKKLLDVCE 94
>FPS_FUJSV (P00530) Tyrosine-protein kinase transforming protein FPS (EC| 2.7.10.2) Length = 873 Score = 34.7 bits (78), Expect = 0.12 Identities = 26/117 (22%), Positives = 49/117 (41%), Gaps = 1/117 (0%) Frame = +3 Query: 105 KPVAXKSNTKPXKAIVYSVADLQIATDSFSMDNLVGEGTFGRVYXSQFN-DGXVLAVKKL 281 +P+ KS +A++ L + + +G G FG V+ + D +AVK Sbjct: 586 RPITRKSGIVLTRAVLKDKWVLN--HEDVLLGERIGRGNFGEVFSGRLRADNTPVAVKSC 643 Query: 282 DCTVIPFQSSDDFVELVSXISILHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 T+ P + F++ + +HPN+ L+G C + +V + + G L Sbjct: 644 RETLPP-ELKAKFLQEARILKQCNHPNIVRLIGVCTQKQPIYIVMELVQGGDFLSFL 699
>NTRK3_HUMAN (Q16288) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (GP145-TrkC) (Trk-C) Length = 839 Score = 34.7 bits (78), Expect = 0.12 Identities = 21/88 (23%), Positives = 44/88 (50%), Gaps = 6/88 (6%) Frame = +3 Query: 207 VGEGTFGRVYXSQF------NDGXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHPNLN 368 +GEG FG+V+ ++ D ++AVK L + + DF ++ L H ++ Sbjct: 544 LGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPTLAARK--DFQREAELLTNLQHEHIV 601 Query: 369 ELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 + G C + ++V+++ ++G L+ L Sbjct: 602 KFYGVCGDGDPLIMVFEYMKHGDLNKFL 629
>SRC1_XENLA (P13115) Tyrosine-protein kinase Src-1 (EC 2.7.10.2) (p60-Src-1)| Length = 531 Score = 34.7 bits (78), Expect = 0.12 Identities = 25/94 (26%), Positives = 44/94 (46%) Frame = +3 Query: 171 QIATDSFSMDNLVGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSSDDFVELVSXISIL 350 +I DS ++ +G+G FG V+ +N +A+K L + S + F++ + L Sbjct: 259 EIPRDSLRLELKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTM---SPEAFLQEAQVMKKL 315 Query: 351 HHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 H L +L E + +V ++ GSL D L Sbjct: 316 RHEKLVQLYAVVSEEPIY-IVTEYISKGSLLDFL 348
>NTRK3_SAIBB (Q5IS82) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) Length = 825 Score = 34.7 bits (78), Expect = 0.12 Identities = 21/88 (23%), Positives = 44/88 (50%), Gaps = 6/88 (6%) Frame = +3 Query: 207 VGEGTFGRVYXSQF------NDGXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHPNLN 368 +GEG FG+V+ ++ D ++AVK L + + DF ++ L H ++ Sbjct: 544 LGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPTLAARK--DFQREAELLTNLQHEHIV 601 Query: 369 ELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 + G C + ++V+++ ++G L+ L Sbjct: 602 KFYGVCGDGDPLIMVFEYMKHGDLNKFL 629
>NTRK3_PANTR (Q5IS37) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) Length = 825 Score = 34.7 bits (78), Expect = 0.12 Identities = 21/88 (23%), Positives = 44/88 (50%), Gaps = 6/88 (6%) Frame = +3 Query: 207 VGEGTFGRVYXSQF------NDGXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHPNLN 368 +GEG FG+V+ ++ D ++AVK L + + DF ++ L H ++ Sbjct: 544 LGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPTLAARK--DFQREAELLTNLQHEHIV 601 Query: 369 ELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 + G C + ++V+++ ++G L+ L Sbjct: 602 KFYGVCGDGDPLIMVFEYMKHGDLNKFL 629
>NTRK3_MACFA (Q5IFJ9) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) Length = 825 Score = 34.7 bits (78), Expect = 0.12 Identities = 21/88 (23%), Positives = 44/88 (50%), Gaps = 6/88 (6%) Frame = +3 Query: 207 VGEGTFGRVYXSQF------NDGXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHPNLN 368 +GEG FG+V+ ++ D ++AVK L + + DF ++ L H ++ Sbjct: 544 LGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPTLAARK--DFQREAELLTNLQHEHIV 601 Query: 369 ELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 + G C + ++V+++ ++G L+ L Sbjct: 602 KFYGVCGDGDPLIMVFEYMKHGDLNKFL 629
>YSK4_HUMAN (Q56UN5) SPS1/STE20-related protein kinase YSK4 (EC 2.7.11.1)| (Regulated in COPD, protein kinase) Length = 1328 Score = 34.3 bits (77), Expect = 0.16 Identities = 20/88 (22%), Positives = 44/88 (50%), Gaps = 4/88 (4%) Frame = +3 Query: 204 LVGEGTFGRVYXSQFNDGXVLAVKKLDC-TVIPFQSSDDFVEL---VSXISILHHPNLNE 371 ++G+G +G VY + G ++AVK++ T + ++ +L V + L H N+ Sbjct: 1066 ILGKGAYGTVYCGLTSQGQLIAVKQVALDTSNKLAAEKEYRKLQEEVDLLKALKHVNIVA 1125 Query: 372 LVGYCMEHGXHLLVYDFHRNGSLHDLLH 455 +G C++ + +F GS+ +++ Sbjct: 1126 YLGTCLQENTVSIFMEFVPGGSISSIIN 1153
>FGFR2_MOUSE (P21803) Fibroblast growth factor receptor 2 precursor (EC| 2.7.10.1) (FGFR-2) (Keratinocyte growth factor receptor) Length = 821 Score = 34.3 bits (77), Expect = 0.16 Identities = 24/98 (24%), Positives = 42/98 (42%), Gaps = 8/98 (8%) Frame = +3 Query: 183 DSFSMDNLVGEGTFGRVYXSQF--------NDGXVLAVKKLDCTVIPFQSSDDFVELVSX 338 D ++ +GEG FG+V ++ + +AVK L SD E+ Sbjct: 479 DKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMM 538 Query: 339 ISILHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 I H N+ L+G C + G ++ ++ G+L + L Sbjct: 539 KMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYL 576
>FGFR2_HUMAN (P21802) Fibroblast growth factor receptor 2 precursor (EC| 2.7.10.1) (FGFR-2) (Keratinocyte growth factor receptor 2) (CD332 antigen) Length = 821 Score = 34.3 bits (77), Expect = 0.16 Identities = 24/98 (24%), Positives = 42/98 (42%), Gaps = 8/98 (8%) Frame = +3 Query: 183 DSFSMDNLVGEGTFGRVYXSQF--------NDGXVLAVKKLDCTVIPFQSSDDFVELVSX 338 D ++ +GEG FG+V ++ + +AVK L SD E+ Sbjct: 479 DKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMM 538 Query: 339 ISILHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 I H N+ L+G C + G ++ ++ G+L + L Sbjct: 539 KMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYL 576
>BMX_HUMAN (P51813) Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2)| (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38) Length = 675 Score = 34.3 bits (77), Expect = 0.16 Identities = 27/115 (23%), Positives = 51/115 (44%) Frame = +3 Query: 108 PVAXKSNTKPXKAIVYSVADLQIATDSFSMDNLVGEGTFGRVYXSQFNDGXVLAVKKLDC 287 PV+ K+N P ++ ++ + ++ +G G FG V ++ +AVK + Sbjct: 391 PVSTKANKVPD-SVSLGNGIWELKREEITLLKELGSGQFGVVQLGKWKGQYDVAVKMIKE 449 Query: 288 TVIPFQSSDDFVELVSXISILHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 + S D+F + + L HP L + G C + +V ++ NG L + L Sbjct: 450 GSM---SEDEFFQEAQTMMKLSHPKLVKFYGVCSKEYPIYIVTEYISNGCLLNYL 501
>YES_HUMAN (P07947) Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2)| (p61-Yes) (c-Yes) Length = 542 Score = 34.3 bits (77), Expect = 0.16 Identities = 27/99 (27%), Positives = 46/99 (46%), Gaps = 1/99 (1%) Frame = +3 Query: 171 QIATDSFSMDNLVGEGTFGRVYXSQFNDGXVLAVKKL-DCTVIPFQSSDDFVELVSXISI 347 +I +S ++ +G+G FG V+ +N +A+K L T++P + F++ + Sbjct: 270 EIPRESLRLEVKLGQGCFGEVWMGTWNGTTKVAIKTLKPGTMMP----EAFLQEAQIMKK 325 Query: 348 LHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLLHLSD 464 L H L L E + +V +F GSL D L D Sbjct: 326 LRHDKLVPLYAVVSEEPIY-IVTEFMSKGSLLDFLKEGD 363
>SRC_RSVSE (P63185) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 34.3 bits (77), Expect = 0.16 Identities = 23/94 (24%), Positives = 45/94 (47%) Frame = +3 Query: 171 QIATDSFSMDNLVGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSSDDFVELVSXISIL 350 +I +S ++ +G+G FG V+ +N +A+K L + S + F++ + L Sbjct: 260 EIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTM---SPEAFLQEAQVMKKL 316 Query: 351 HHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 H L +L E ++++ ++ GSL D L Sbjct: 317 RHKKLVQLYAVVSEEPIYIVI-EYMSKGSLLDFL 349
>ICL1_KLULA (Q6CWQ4) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 361 Score = 34.3 bits (77), Expect = 0.16 Identities = 21/90 (23%), Positives = 42/90 (46%), Gaps = 2/90 (2%) Frame = +3 Query: 189 FSMDNLVGEGTFGRVYXSQFND-GXVLAVKKLD-CTVIPFQSSDDFVELVSXISILHHPN 362 F + ++G+G FG+VY + + G + A+K ++ ++ + F V H N Sbjct: 100 FEIGKILGKGKFGKVYCVKHRETGLICALKAMEKKEIVQYTIQKQFRREVEIQGSFKHKN 159 Query: 363 LNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 L +L G+ + L+ ++ G L+ L Sbjct: 160 LTQLYGFFYDEKRVYLLMEYVYYGELYKFL 189
>SN1L1_RAT (Q9R1U5) Serine/threonine-protein kinase SNF1-like kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase SNF1LK) (Salt-inducible protein kinase) (Protein kinase KID2) Length = 776 Score = 34.3 bits (77), Expect = 0.16 Identities = 23/97 (23%), Positives = 46/97 (47%), Gaps = 5/97 (5%) Frame = +3 Query: 189 FSMDNLVGEGTFGRVYXSQFN-DGXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHPNL 365 + ++ +G+G F V ++ +A+K +D T + + + V + +L+HPN+ Sbjct: 27 YDVERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTRLDSSNLEKIYREVQLMKLLNHPNI 86 Query: 366 NELVGYCMEHGXHLLVYDFHRNGSLHDLL----HLSD 464 +L +V +F +NG + D L HLS+ Sbjct: 87 IKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSE 123
>FGFR2_XENLA (Q03364) Fibroblast growth factor receptor 2 precursor (EC| 2.7.10.1) (FGFR-2) Length = 813 Score = 34.3 bits (77), Expect = 0.16 Identities = 24/106 (22%), Positives = 47/106 (44%), Gaps = 12/106 (11%) Frame = +3 Query: 171 QIATDSFSMDNLVGEGTFGRVYXSQF--------NDGXVLAVKKLDCTVIPFQSSDDFVE 326 + + D ++ +GEG FG+V ++ + +AVK L + D + Sbjct: 465 EFSRDKLTLGKPLGEGCFGQVVMAEALGIDKERPKESVTVAVKMLKDNA----TEKDLAD 520 Query: 327 LVSXISILH----HPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 LVS + ++ H N+ L+G C + G ++ ++ G+L L Sbjct: 521 LVSEMEMMKMIGKHKNIINLLGACTQGGTLYVIVEYAAKGNLRQYL 566
>CDK3_MOUSE (Q80YP0) Truncated cell division protein kinase 3 homolog| Length = 186 Score = 34.3 bits (77), Expect = 0.16 Identities = 22/81 (27%), Positives = 39/81 (48%), Gaps = 1/81 (1%) Frame = +3 Query: 183 DSFSMDNLVGEGTFGRVYXSQFN-DGXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHP 359 D F +GEGT+G VY ++ G ++A+KK+ + V +S + L HP Sbjct: 2 DVFQKVEKIGEGTYGVVYKARNKVTGQLVALKKIRLDLEAEGVPSTAVREISLLKELKHP 61 Query: 360 NLNELVGYCMEHGXHLLVYDF 422 N+ +L+ +V++F Sbjct: 62 NIIKLLDVVHREKKLYMVFEF 82
>FGFR4_RAT (Q498D6) Fibroblast growth factor receptor 4 precursor (EC| 2.7.10.1) (FGFR-4) Length = 800 Score = 34.3 bits (77), Expect = 0.16 Identities = 28/105 (26%), Positives = 46/105 (43%), Gaps = 17/105 (16%) Frame = +3 Query: 189 FSMDNLV-----GEGTFGRVY--------XSQFNDGXVLAVKKLDCTVIPFQSSDDFVEL 329 F D LV GEG FG+V S+ + +AVK L S D +L Sbjct: 460 FPRDRLVLGKPLGEGCFGQVVRAEALGMDSSRPDQTSTVAVKMLKDNA----SDKDLADL 515 Query: 330 VSXISIL----HHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 +S + ++ H N+ L+G C + G ++ ++ G+L + L Sbjct: 516 ISEMEMMKLIGRHKNIINLLGVCTQEGPLYVIVEYAAKGNLREFL 560
>CDC2_PONPY (Q5RCH1) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 34.3 bits (77), Expect = 0.16 Identities = 20/73 (27%), Positives = 34/73 (46%), Gaps = 1/73 (1%) Frame = +3 Query: 207 VGEGTFGRVYXSQFND-GXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHPNLNELVGY 383 +GEGT+G VY + G V+ +KK+ + +S + L HPN+ L Sbjct: 10 IGEGTYGVVYKGRHKTTGQVVTMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDV 69 Query: 384 CMEHGXHLLVYDF 422 M+ L+++F Sbjct: 70 LMQDSRLYLIFEF 82
>SLK_HUMAN (Q9H2G2) STE20-like serine/threonine-protein kinase (EC 2.7.11.1)| (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (hSLK) (Serine/threonine-protein kinase 2) (CTCL tumor antigen se20-9) Length = 1235 Score = 34.3 bits (77), Expect = 0.16 Identities = 19/57 (33%), Positives = 32/57 (56%) Frame = +3 Query: 207 VGEGTFGRVYXSQFNDGXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHPNLNELV 377 +G+G FG+VY +Q + VLA K+ T + D VE + ++ HPN+ +L+ Sbjct: 40 LGDGAFGKVYKAQNKETSVLAAAKVIDTKSEEELEDYMVE-IDILASCDHPNIVKLL 95
>CEK3_CHICK (P18461) Tyrosine kinase receptor CEK3 precursor (EC 2.7.10.1)| Length = 823 Score = 34.3 bits (77), Expect = 0.16 Identities = 24/98 (24%), Positives = 42/98 (42%), Gaps = 8/98 (8%) Frame = +3 Query: 183 DSFSMDNLVGEGTFGRVYXSQF--------NDGXVLAVKKLDCTVIPFQSSDDFVELVSX 338 D ++ +GEG FG+V ++ + +AVK L SD E+ Sbjct: 481 DKLTLGKPLGEGCFGQVVMAEAVGIDKDRPKEAVTVAVKMLKDDATEKDLSDLVSEMEMM 540 Query: 339 ISILHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 I H N+ L+G C + G ++ ++ G+L + L Sbjct: 541 KMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYL 578
>CDK2_CARAU (P43450) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 34.3 bits (77), Expect = 0.16 Identities = 22/81 (27%), Positives = 38/81 (46%), Gaps = 1/81 (1%) Frame = +3 Query: 183 DSFSMDNLVGEGTFGRVYXSQFN-DGXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHP 359 +SF +GEGT+G VY ++ G +A+KK+ + +S + L+HP Sbjct: 2 ESFQKVEKIGEGTYGVVYKAKNKVTGETVALKKIRLDTETEGVPSTAIREISLLKELNHP 61 Query: 360 NLNELVGYCMEHGXHLLVYDF 422 N+ +L LV++F Sbjct: 62 NIVKLHDVIHTENKLYLVFEF 82
>YES_AVISY (P00527) Tyrosine-protein kinase transforming protein YES (EC| 2.7.10.2) (Fragment) Length = 528 Score = 34.3 bits (77), Expect = 0.16 Identities = 26/95 (27%), Positives = 45/95 (47%), Gaps = 1/95 (1%) Frame = +3 Query: 171 QIATDSFSMDNLVGEGTFGRVYXSQFNDGXVLAVKKLDC-TVIPFQSSDDFVELVSXISI 347 +I +S ++ +G+G FG V+ +N +A+K L T++P + F++ + Sbjct: 261 EIPRESLRLEVKLGQGCFGEVWMGTWNGTTKVAIKTLKLGTMMP----EAFLQEAQIMKK 316 Query: 348 LHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLL 452 L H L L E + +V +F GSL D L Sbjct: 317 LRHDKLVPLYAVVSEEPIY-IVTEFMTKGSLLDFL 350
>NEK1_HUMAN (Q96PY6) Serine/threonine-protein kinase Nek1 (EC 2.7.11.1)| (NimA-related protein kinase 1) (NY-REN-55 antigen) Length = 1258 Score = 34.3 bits (77), Expect = 0.16 Identities = 18/79 (22%), Positives = 40/79 (50%), Gaps = 1/79 (1%) Frame = +3 Query: 207 VGEGTFGR-VYXSQFNDGXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHPNLNELVGY 383 +GEG+FG+ + DG +K+++ + + + ++ V+ ++ + HPN+ + Sbjct: 10 IGEGSFGKAILVKSTEDGRQYVIKEINISRMSSKEREESRREVAVLANMKHPNIVQYRES 69 Query: 384 CMEHGXHLLVYDFHRNGSL 440 E+G +V D+ G L Sbjct: 70 FEENGSLYIVMDYCEGGDL 88
>FAK2_HUMAN (Q14289) Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal| adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinas Length = 1009 Score = 34.3 bits (77), Expect = 0.16 Identities = 23/86 (26%), Positives = 43/86 (50%), Gaps = 6/86 (6%) Frame = +3 Query: 174 IATDSFSMDNLVGEGTFGRVYXSQF----NDGXVLAVK--KLDCTVIPFQSSDDFVELVS 335 IA + ++ ++GEG FG VY + + +AVK K DCT+ + + F+ Sbjct: 420 IAREDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTL---DNKEKFMSEAV 476 Query: 336 XISILHHPNLNELVGYCMEHGXHLLV 413 + L HP++ +L+G E +++ Sbjct: 477 IMKNLDHPHIVKLIGIIEEEPTWIIM 502
>AURKC_HUMAN (Q9UQB9) Serine/threonine-protein kinase 13 (EC 2.7.11.1)| (Aurora/Ipl1/Eg2 protein 2) (Aurora/Ipl1-related kinase 3) (Aurora-C) Length = 309 Score = 34.3 bits (77), Expect = 0.16 Identities = 28/107 (26%), Positives = 50/107 (46%), Gaps = 4/107 (3%) Frame = +3 Query: 156 SVADLQIATDSFSMDNLVGEGTFGRVYXSQFNDG-XVLAVKKLDCTVIPFQSSDDFVELV 332 S A ++ D F + +G+G FG VY ++ + ++A+K L + I + + +L Sbjct: 32 SPAMRRLTVDDFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEH--QLR 89 Query: 333 SXISI---LHHPNLNELVGYCMEHGXHLLVYDFHRNGSLHDLLHLSD 464 I I L HPN+ L Y + L+ ++ G L+ L S+ Sbjct: 90 REIEIQAHLQHPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSE 136
>FPS_AVISP (P00541) Tyrosine-protein kinase transforming protein Fps (EC| 2.7.10.2) Length = 533 Score = 34.3 bits (77), Expect = 0.16 Identities = 21/83 (25%), Positives = 37/83 (44%), Gaps = 1/83 (1%) Frame = +3 Query: 207 VGEGTFGRVYXSQFN-DGXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHPNLNELVGY 383 +G G FG V+ + D +AVK T+ P + F++ + +HPN+ L+G Sbjct: 278 IGRGNFGEVFSGRLRADNTPVAVKSCRETLPP-ELKAKFLQEARILKQYNHPNIVRLIGV 336 Query: 384 CMEHGXHLLVYDFHRNGSLHDLL 452 C + +V + + G L Sbjct: 337 CTQKQPIYIVMELVQGGDFLSFL 359
>CDC2C_DROME (P23573) Cell division control protein 2 cognate (EC 2.7.11.22) (EC| 2.7.11.23) Length = 314 Score = 34.3 bits (77), Expect = 0.16 Identities = 20/81 (24%), Positives = 39/81 (48%), Gaps = 1/81 (1%) Frame = +3 Query: 183 DSFSMDNLVGEGTFGRVYXSQFND-GXVLAVKKLDCTVIPFQSSDDFVELVSXISILHHP 359 D+F +GEGT+G VY ++ N G +A+KK+ + +S + L HP Sbjct: 6 DNFQRAEKIGEGTYGIVYKARSNSTGQDVALKKIRLEGETEGVPSTAIREISLLKNLKHP 65 Query: 360 NLNELVGYCMEHGXHLLVYDF 422 N+ +L + +++++ Sbjct: 66 NVVQLFDVVISGNNLYMIFEY 86 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 63,651,699 Number of Sequences: 219361 Number of extensions: 1118918 Number of successful extensions: 3460 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 3277 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 3341 length of database: 80,573,946 effective HSP length: 102 effective length of database: 58,199,124 effective search space used: 3026354448 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
