ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | basd27o11 |
|---|---|
| Clone Library Name | barley_pub |
>CDPK_DAUCA (P28582) Calcium-dependent protein kinase (EC 2.7.11.1) (CDPK)| Length = 532 Score = 303 bits (775), Expect = 3e-82 Identities = 142/199 (71%), Positives = 175/199 (87%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRRYGAEADIWSAG 181 ENFL +K +D+ LKATDFGLSVF + G+ +R++VGSAYYVAPEVL+R YG E DIWSAG Sbjct: 209 ENFLLSSKDKDAMLKATDFGLSVFIEEGKVYRNIVGSAYYVAPEVLRRSYGKEIDIWSAG 268 Query: 182 VILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERL 361 VILYILLSGVPPFWAENE+GIFDA+L+G IDF S+PWPS+SN AKDLV++ML QDP+ R+ Sbjct: 269 VILYILLSGVPPFWAENEKGIFDAILEGVIDFESEPWPSVSNSAKDLVRKMLTQDPRRRI 328 Query: 362 TAAEILNHPWIREDGEAPDKPLDITVISRMKQFRAMNKLKKVALKIVAESLSEEEIVGLR 541 T+A++L+HPW+RE GEA DKP+D V+SRMKQFRAMNKLK++ALK++AESLSEEEI GL+ Sbjct: 329 TSAQVLDHPWMREGGEASDKPIDSAVLSRMKQFRAMNKLKQLALKVIAESLSEEEIKGLK 388 Query: 542 EMFKSLDTDNSGTITLDEL 598 MF ++DTD SGTIT +EL Sbjct: 389 SMFANMDTDKSGTITYEEL 407
>CDPK2_ORYSA (P53683) Calcium-dependent protein kinase, isoform 2 (EC 2.7.11.1)| (CDPK 2) Length = 533 Score = 300 bits (768), Expect = 2e-81 Identities = 141/199 (70%), Positives = 172/199 (86%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRRYGAEADIWSAG 181 ENFL K E++ LKATDFGLSVF + G+ +RD+VGSAYYVAPEVL+R YG E D+WSAG Sbjct: 213 ENFLLATKEENAMLKATDFGLSVFIEEGKMYRDIVGSAYYVAPEVLRRNYGKEIDVWSAG 272 Query: 182 VILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERL 361 VILYILLSGVPPFWAE E+GIFDA+L+G IDF S PWPSIS AKDLV++ML QDPK+R+ Sbjct: 273 VILYILLSGVPPFWAETEKGIFDAILQGEIDFESQPWPSISESAKDLVRKMLTQDPKKRI 332 Query: 362 TAAEILNHPWIREDGEAPDKPLDITVISRMKQFRAMNKLKKVALKIVAESLSEEEIVGLR 541 T+A++L HPW+R DGEA DKP+D V+SRMKQFRAMNKLKK+ALK++A +L+EEEI GL+ Sbjct: 333 TSAQVLQHPWLR-DGEASDKPIDSAVLSRMKQFRAMNKLKKMALKVIASNLNEEEIKGLK 391 Query: 542 EMFKSLDTDNSGTITLDEL 598 +MF ++DTDNSGTIT +EL Sbjct: 392 QMFTNMDTDNSGTITYEEL 410
>CDPK1_ARATH (Q06850) Calcium-dependent protein kinase, isoform AK1 (EC| 2.7.11.1) (CDPK) Length = 610 Score = 297 bits (760), Expect = 2e-80 Identities = 140/199 (70%), Positives = 168/199 (84%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRRYGAEADIWSAG 181 ENFLF++K EDS LK DFGLS+FFKP + F D+VGS YYVAPEVL++RYG EAD+WSAG Sbjct: 278 ENFLFVSKHEDSLLKTIDFGLSMFFKPDDVFTDVVGSPYYVAPEVLRKRYGPEADVWSAG 337 Query: 182 VILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERL 361 VI+YILLSGVPPFWAE E+GIF+ VL G +DFSSDPWPSIS AKDLV++ML +DPK+RL Sbjct: 338 VIVYILLSGVPPFWAETEQGIFEQVLHGDLDFSSDPWPSISESAKDLVRKMLVRDPKKRL 397 Query: 362 TAAEILNHPWIREDGEAPDKPLDITVISRMKQFRAMNKLKKVALKIVAESLSEEEIVGLR 541 TA ++L HPW++ DG APDKPLD V+SRMKQF AMNK KK+AL+++AESLSEEEI GL+ Sbjct: 398 TAHQVLCHPWVQVDGVAPDKPLDSAVLSRMKQFSAMNKFKKMALRVIAESLSEEEIAGLK 457 Query: 542 EMFKSLDTDNSGTITLDEL 598 EMF +D D SG IT +EL Sbjct: 458 EMFNMIDADKSGQITFEEL 476
>CDPK_SOYBN (P28583) Calcium-dependent protein kinase SK5 (EC 2.7.11.1) (CDPK)| Length = 508 Score = 294 bits (753), Expect = 1e-79 Identities = 141/199 (70%), Positives = 168/199 (84%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRRYGAEADIWSAG 181 ENFLF ED+ LKATDFGLSVF+KPGE F D+VGS YYVAPEVL++ YG E+D+WSAG Sbjct: 162 ENFLFDTIDEDAKLKATDFGLSVFYKPGESFCDVVGSPYYVAPEVLRKLYGPESDVWSAG 221 Query: 182 VILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERL 361 VILYILLSGVPPFWAE+E GIF +L G +DF S+PWPSIS+ AKDL+++ML Q+PK RL Sbjct: 222 VILYILLSGVPPFWAESEPGIFRQILLGKLDFHSEPWPSISDSAKDLIRKMLDQNPKTRL 281 Query: 362 TAAEILNHPWIREDGEAPDKPLDITVISRMKQFRAMNKLKKVALKIVAESLSEEEIVGLR 541 TA E+L HPWI +D APDKPLD V+SR+KQF AMNKLKK+AL+++AE LSEEEI GL+ Sbjct: 282 TAHEVLRHPWIVDDNIAPDKPLDSAVLSRLKQFSAMNKLKKMALRVIAERLSEEEIGGLK 341 Query: 542 EMFKSLDTDNSGTITLDEL 598 E+FK +DTDNSGTIT DEL Sbjct: 342 ELFKMIDTDNSGTITFDEL 360
>CDPK2_MAIZE (P49101) Calcium-dependent protein kinase 2 (EC 2.7.11.1) (CDPK 2)| Length = 513 Score = 292 bits (748), Expect = 4e-79 Identities = 138/199 (69%), Positives = 168/199 (84%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRRYGAEADIWSAG 181 ENFL E++ LKATDFGLSVF + G+ +RD+VGSAYYVAPEVL+R YG E D+WSAG Sbjct: 193 ENFLLATMEENAMLKATDFGLSVFIEEGKMYRDIVGSAYYVAPEVLRRSYGKEIDVWSAG 252 Query: 182 VILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERL 361 VILYILLSGVPPFWAE E+GIFDA+L IDF S PWPSIS AKDLV++ML +DPK+RL Sbjct: 253 VILYILLSGVPPFWAEIEKGIFDAILHEEIDFESQPWPSISESAKDLVRKMLTRDPKKRL 312 Query: 362 TAAEILNHPWIREDGEAPDKPLDITVISRMKQFRAMNKLKKVALKIVAESLSEEEIVGLR 541 T+A++L H W+RE GEA DKP+D V+SRMKQFRAMNKLKK+ALK++A +L+EEEI GL+ Sbjct: 313 TSAQVLQHQWLREGGEASDKPIDSAVLSRMKQFRAMNKLKKMALKVIASNLNEEEIKGLK 372 Query: 542 EMFKSLDTDNSGTITLDEL 598 +MF ++DTDNSGTIT +EL Sbjct: 373 QMFMNMDTDNSGTITYEEL 391
>CDPK3_ORYSA (P53684) Calcium-dependent protein kinase, isoform 11 (EC 2.7.11.1)| (CDPK 11) Length = 542 Score = 291 bits (744), Expect = 1e-78 Identities = 139/199 (69%), Positives = 165/199 (82%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRRYGAEADIWSAG 181 ENFL L+K +D +KA DFGLSVFFKPG+ F +LVGS YYVAPEVL +RYG E+D+WSAG Sbjct: 207 ENFLLLDKDDDLSIKAIDFGLSVFFKPGQVFTELVGSPYYVAPEVLHKRYGPESDVWSAG 266 Query: 182 VILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERL 361 VILY+LLSGVPPFWAE ++GIFDAVLKGHIDF SDPWP IS+ AKDL+++ML P ERL Sbjct: 267 VILYVLLSGVPPFWAETQQGIFDAVLKGHIDFQSDPWPKISDSAKDLIRKMLSHCPSERL 326 Query: 362 TAAEILNHPWIREDGEAPDKPLDITVISRMKQFRAMNKLKKVALKIVAESLSEEEIVGLR 541 A E+L HPWI E+G A D+ LD +VISR+KQF AMNKLKK+AL+++AE LSEEEI GLR Sbjct: 327 KAHEVLRHPWICENGVATDQALDPSVISRLKQFSAMNKLKKLALRVIAERLSEEEIAGLR 386 Query: 542 EMFKSLDTDNSGTITLDEL 598 EMFK++DT N G IT EL Sbjct: 387 EMFKAVDTKNRGVITFGEL 405
>CDPK1_ORYSA (P53682) Calcium-dependent protein kinase, isoform 1 (EC 2.7.11.1)| (CDPK 1) Length = 534 Score = 260 bits (664), Expect = 2e-69 Identities = 122/199 (61%), Positives = 160/199 (80%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRRYGAEADIWSAG 181 ENFL L+ ++ +KA DFGLSVFF+PG+ FR++VGS YY+APEVL++RYG EADIW+AG Sbjct: 201 ENFLLLDADDEFSVKAIDFGLSVFFRPGQVFREVVGSPYYIAPEVLEKRYGPEADIWTAG 260 Query: 182 VILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERL 361 VILY+LL+GVPPFWA+ + GI++ VL G IDF S+ WP IS+ AKDL+K+ML P ERL Sbjct: 261 VILYVLLTGVPPFWADTQSGIYEKVLDGRIDFKSNRWPRISDSAKDLIKKMLCPYPSERL 320 Query: 362 TAAEILNHPWIREDGEAPDKPLDITVISRMKQFRAMNKLKKVALKIVAESLSEEEIVGLR 541 A E+L HPWI ++G A ++ LD +V+ R+KQF AMN+LKK++L+I+AE LSEEEIVGLR Sbjct: 321 KAHEVLKHPWICDNGVATNRALDPSVLPRLKQFSAMNRLKKLSLQIIAERLSEEEIVGLR 380 Query: 542 EMFKSLDTDNSGTITLDEL 598 EMFK++DT N +T EL Sbjct: 381 EMFKAMDTKNRSVVTFGEL 399
>CRK_DAUCA (P53681) CDPK-related protein kinase (EC 2.7.11.1) (PK421)| Length = 602 Score = 209 bits (533), Expect = 4e-54 Identities = 104/199 (52%), Positives = 138/199 (69%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRRYGAEADIWSAG 181 ENFLF +K EDS LKA DFGLS + KP E+ D+VGSAYYVAPEVL R Y EAD+WS G Sbjct: 280 ENFLFKSKDEDSQLKAIDFGLSDYVKPDERLNDIVGSAYYVAPEVLHRSYSTEADVWSIG 339 Query: 182 VILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERL 361 VI YILL G PFWA E GIF AVLK ++ F PWPS+S+ AKD VKR+L +DP++R+ Sbjct: 340 VISYILLCGSRPFWARTESGIFRAVLKANLSFDEPPWPSVSSEAKDFVKRLLNKDPRKRM 399 Query: 362 TAAEILNHPWIREDGEAPDKPLDITVISRMKQFRAMNKLKKVALKIVAESLSEEEIVGLR 541 TAA+ L H WI+ + PLDI V MK + + L+K AL+ ++++L+ +E+ L+ Sbjct: 400 TAAQALCHSWIKNSNDI-KFPLDILVFKLMKVYMRSSPLRKAALRALSKTLTVDELFYLK 458 Query: 542 EMFKSLDTDNSGTITLDEL 598 E F L+ +GTI+L+ + Sbjct: 459 EQFVLLEPTKNGTISLENI 477
>CDPK2_PLAF7 (Q8ICR0) Calcium-dependent protein kinase 2 (EC 2.7.11.1) (PfCDPK2)| Length = 508 Score = 171 bits (434), Expect = 1e-42 Identities = 88/200 (44%), Positives = 126/200 (63%), Gaps = 1/200 (0%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRRYGAEADIWSAG 181 ENFLF ++ +DS LK DFGLS GE G+ YYVAP+VL +Y + DIWS+G Sbjct: 195 ENFLFQSENKDSLLKIIDFGLSKNLGTGEFTTTKAGTPYYVAPQVLDGKYDKKCDIWSSG 254 Query: 182 VILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERL 361 VI+Y LL G PPF+ + + + V KG F + W SIS+ AK+L+ ++L +P ER Sbjct: 255 VIMYTLLCGYPPFYGDTDNEVLKKVKKGEFCFYENDWGSISSDAKNLITKLLTYNPNERC 314 Query: 362 TAAEILNHPWIREDGEAPDK-PLDITVISRMKQFRAMNKLKKVALKIVAESLSEEEIVGL 538 T E LNHPWI + ++ + L T++ +K F+ N+LKK+AL I+A+ L + EI L Sbjct: 315 TIEEALNHPWITQMTKSHEHVELSSTLLKNLKNFKKENELKKIALTIIAKHLCDVEINNL 374 Query: 539 REMFKSLDTDNSGTITLDEL 598 R +F +LD DNSGT++ E+ Sbjct: 375 RNIFIALDVDNSGTLSSQEI 394
>CDPK2_PLAFK (O15865) Calcium-dependent protein kinase 2 (EC 2.7.11.1) (PfCDPK2)| Length = 512 Score = 171 bits (434), Expect = 1e-42 Identities = 88/200 (44%), Positives = 126/200 (63%), Gaps = 1/200 (0%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRRYGAEADIWSAG 181 ENFLF ++ +DS LK DFGLS GE G+ YYVAP+VL +Y + DIWS+G Sbjct: 195 ENFLFQSENKDSLLKIIDFGLSKNLGTGEFTTTKAGTPYYVAPQVLDGKYDKKCDIWSSG 254 Query: 182 VILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERL 361 VI+Y LL G PPF+ + + + V KG F + W SIS+ AK+L+ ++L +P ER Sbjct: 255 VIMYTLLCGYPPFYGDTDNEVLKKVKKGEFCFYENDWGSISSDAKNLITKLLTYNPNERC 314 Query: 362 TAAEILNHPWIREDGEAPDK-PLDITVISRMKQFRAMNKLKKVALKIVAESLSEEEIVGL 538 T E LNHPWI + ++ + L T++ +K F+ N+LKK+AL I+A+ L + EI L Sbjct: 315 TIEEALNHPWITQMTKSHEHVELSSTLLKNLKNFKKENELKKIALTIIAKHLCDVEINNL 374 Query: 539 REMFKSLDTDNSGTITLDEL 598 R +F +LD DNSGT++ E+ Sbjct: 375 RNIFIALDVDNSGTLSSQEI 394
>CDPK3_PLAYO (Q7RAV5) Calcium-dependent protein kinase 3 (EC 2.7.11.1)| Length = 538 Score = 154 bits (388), Expect = 2e-37 Identities = 79/202 (39%), Positives = 123/202 (60%), Gaps = 3/202 (1%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGE-QFRDLVGSAYYVAPEVLKRRYGAEADIWSA 178 ENFLF +K +S +K DFGL+ +F + + + G+ YYVAP+VL Y + D+WSA Sbjct: 236 ENFLFYDKSTESLIKIIDFGLAAYFNDIDYEMKTKAGTPYYVAPQVLTGCYDYKCDLWSA 295 Query: 179 GVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKER 358 GV+ YI+L G PPF+ E++ I V KG +F W +IS+ AKDL+KR L D +R Sbjct: 296 GVLFYIILCGYPPFYGESDHEILSMVKKGKYNFKGKEWNNISDEAKDLIKRCLTIDSGKR 355 Query: 359 LTAAEILNHPWIREDGEA--PDKPLDITVISRMKQFRAMNKLKKVALKIVAESLSEEEIV 532 + A+E L HPW ++ + D +DI V+ K + + KL+K+A+ I+A+ ++ ++ Sbjct: 356 INASEALKHPWFKKKKGSFNLDVKMDIHVLENFKNYALLLKLQKLAMTIIAQQSNDYDLQ 415 Query: 533 GLREMFKSLDTDNSGTITLDEL 598 L+ +F LD D G IT ++L Sbjct: 416 QLKAVFLYLDEDGKGNITKNQL 437
>CDPK1_PLAFK (P62343) Calcium-dependent protein kinase 1 (EC 2.7.11.1) (PfCPK)| (PfCDPK1) Length = 523 Score = 152 bits (383), Expect = 9e-37 Identities = 83/203 (40%), Positives = 117/203 (57%), Gaps = 4/203 (1%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRRYGAEADIWSAG 181 EN L NK +K DFGLS FF + RD +G+AYY+APEVL+++Y + D+WS G Sbjct: 194 ENILLENKHSLLNIKIVDFGLSSFFSKDNKLRDRLGTAYYIAPEVLRKKYNEKCDVWSCG 253 Query: 182 VILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERL 361 VILYILL G PPF +N++ I V KG F + W +IS AK+L+K ML D +R+ Sbjct: 254 VILYILLCGYPPFGGQNDQDIIKKVEKGKYYFDFNDWKNISEEAKELIKLMLTYDYNKRI 313 Query: 362 TAAEILNHPWIREDGEAPDKPLDITV---ISRMKQFRAMNKLKKVALKIVAESLSE-EEI 529 TA E LN WI++ +K T+ +S M++F KL + A+ + L+ EE Sbjct: 314 TAKEALNSKWIKKYANNINKSDQKTLCGALSNMRKFEGSQKLAQAAILFIGSKLTTLEER 373 Query: 530 VGLREMFKSLDTDNSGTITLDEL 598 L ++FK LD + G + EL Sbjct: 374 KELTDIFKKLDKNGDGQLDKKEL 396
>CDPK1_PLAF7 (P62344) Calcium-dependent protein kinase 1 (EC 2.7.11.1)| Length = 523 Score = 152 bits (383), Expect = 9e-37 Identities = 83/203 (40%), Positives = 117/203 (57%), Gaps = 4/203 (1%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRRYGAEADIWSAG 181 EN L NK +K DFGLS FF + RD +G+AYY+APEVL+++Y + D+WS G Sbjct: 194 ENILLENKHSLLNIKIVDFGLSSFFSKDNKLRDRLGTAYYIAPEVLRKKYNEKCDVWSCG 253 Query: 182 VILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERL 361 VILYILL G PPF +N++ I V KG F + W +IS AK+L+K ML D +R+ Sbjct: 254 VILYILLCGYPPFGGQNDQDIIKKVEKGKYYFDFNDWKNISEEAKELIKLMLTYDYNKRI 313 Query: 362 TAAEILNHPWIREDGEAPDKPLDITV---ISRMKQFRAMNKLKKVALKIVAESLSE-EEI 529 TA E LN WI++ +K T+ +S M++F KL + A+ + L+ EE Sbjct: 314 TAKEALNSKWIKKYANNINKSDQKTLCGALSNMRKFEGSQKLAQAAILFIGSKLTTLEER 373 Query: 530 VGLREMFKSLDTDNSGTITLDEL 598 L ++FK LD + G + EL Sbjct: 374 KELTDIFKKLDKNGDGQLDKKEL 396
>CDPK3_PLAF7 (Q9NJU9) Calcium-dependent protein kinase 3 (EC 2.7.11.1) (PfCDPK3)| Length = 562 Score = 150 bits (380), Expect = 2e-36 Identities = 78/202 (38%), Positives = 117/202 (57%), Gaps = 3/202 (1%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGE-QFRDLVGSAYYVAPEVLKRRYGAEADIWSA 178 ENFLF + +S +K DFGL+ +F + + G+ YYVAP+VL Y + D+WS+ Sbjct: 242 ENFLFYDMTPESLIKIIDFGLASYFTHNNYEMKTKAGTPYYVAPQVLTGSYNYKCDMWSS 301 Query: 179 GVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKER 358 GV+ YILL G PPF+ E++ I V KG F W +IS AKDL+KR L D +R Sbjct: 302 GVLFYILLCGYPPFFGESDHEILSMVKKGKYQFKGKEWNNISEEAKDLIKRCLTMDADKR 361 Query: 359 LTAAEILNHPWIREDGEA--PDKPLDITVISRMKQFRAMNKLKKVALKIVAESLSEEEIV 532 + A+E L HPW ++ A D +DI V+ K + + K +K+A+ I+A+ ++ ++ Sbjct: 362 ICASEALQHPWFKKKKYAFNMDMKMDIHVLENFKNYGLLLKFQKLAMTIIAQQSNDYDVE 421 Query: 533 GLREMFKSLDTDNSGTITLDEL 598 L+ F LD D G IT ++L Sbjct: 422 KLKSTFLVLDEDGKGYITKEQL 443
>CDPK1_PLAYO (Q7RAH3) Calcium-dependent protein kinase 1 (EC 2.7.11.1)| Length = 534 Score = 150 bits (379), Expect = 3e-36 Identities = 83/203 (40%), Positives = 117/203 (57%), Gaps = 4/203 (1%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRRYGAEADIWSAG 181 EN L NK +K DFGLS FF + RD +G+AYY+APEVLK++Y + D+WS G Sbjct: 193 ENILLENKNSLLNIKIVDFGLSSFFSKDYKLRDRLGTAYYIAPEVLKKKYNEKCDVWSCG 252 Query: 182 VILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERL 361 VI+YILL G PPF +N++ I V KG F + W +IS+ AK+L+K ML D +R Sbjct: 253 VIMYILLCGYPPFGGQNDQDIIKKVEKGKYYFDFNDWKNISDEAKELIKLMLTYDYNKRC 312 Query: 362 TAAEILNHPWIREDGEAPDKPLDITV---ISRMKQFRAMNKLKKVALKIVAESLSE-EEI 529 TA E LN WI++ +K T+ +S M++F KL + A+ + L+ EE Sbjct: 313 TAEEALNSRWIKKYANNINKSDQKTLCGALSNMRKFEGSQKLAQAAILFIGSKLTTLEER 372 Query: 530 VGLREMFKSLDTDNSGTITLDEL 598 L ++FK LD + G + EL Sbjct: 373 KELTDIFKKLDKNGDGQLDKKEL 395
>CDPK4_PLAYO (Q7RJG2) Calcium-dependent protein kinase 4 (EC 2.7.11.1)| Length = 527 Score = 137 bits (346), Expect = 2e-32 Identities = 82/205 (40%), Positives = 115/205 (56%), Gaps = 6/205 (2%) Frame = +2 Query: 2 ENFLFLNK-REDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRRYGAEADIWSA 178 EN L K +ED +K DFGLS F+ ++ +D +G+AYY+AP+VL Y + DIWS Sbjct: 196 ENILLETKNKEDMIIKIIDFGLSTHFEYSKKMKDKIGTAYYIAPDVLHGTYDEKCDIWSC 255 Query: 179 GVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKER 358 GVILYILLSG PPF NE I V G F + IS+ AKDL+K+ML R Sbjct: 256 GVILYILLSGCPPFNGSNEYDILKKVETGKYTFDLPQFKKISDKAKDLIKKMLMYTSAVR 315 Query: 359 LTAAEILNHPWIR----EDGEAPDKPLDITVISRMKQFRAMNKLKKVALKIVAESLSE-E 523 ++A + L H WIR +D D P I+ +KQF++ KL + AL + L+ + Sbjct: 316 ISARDALEHEWIRLMTSKDNVNIDIPSLELSITNIKQFQSTQKLAQAALLYMGSKLTTID 375 Query: 524 EIVGLREMFKSLDTDNSGTITLDEL 598 E L ++FK +D + G + +EL Sbjct: 376 ETKELTKIFKKMDKNGDGQLDRNEL 400
>CDPK4_PLABA (P62345) Calcium-dependent protein kinase 4 (EC 2.7.11.1) (PbCDPK4)| Length = 527 Score = 137 bits (346), Expect = 2e-32 Identities = 82/205 (40%), Positives = 115/205 (56%), Gaps = 6/205 (2%) Frame = +2 Query: 2 ENFLFLNK-REDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRRYGAEADIWSA 178 EN L K +ED +K DFGLS F+ ++ +D +G+AYY+AP+VL Y + DIWS Sbjct: 196 ENILLETKNKEDMIIKIIDFGLSTHFEYSKKMKDKIGTAYYIAPDVLHGTYDEKCDIWSC 255 Query: 179 GVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKER 358 GVILYILLSG PPF NE I V G F + IS+ AKDL+K+ML R Sbjct: 256 GVILYILLSGCPPFNGSNEYDILKKVETGKYTFDLPQFKKISDKAKDLIKKMLMYTSAVR 315 Query: 359 LTAAEILNHPWIR----EDGEAPDKPLDITVISRMKQFRAMNKLKKVALKIVAESLSE-E 523 ++A + L H WIR +D D P I+ +KQF++ KL + AL + L+ + Sbjct: 316 ISARDALEHEWIRLMTSKDNVNIDIPSLELSITNIKQFQSTQKLAQAALLYMGSKLTTID 375 Query: 524 EIVGLREMFKSLDTDNSGTITLDEL 598 E L ++FK +D + G + +EL Sbjct: 376 ETKELTKIFKKMDKNGDGQLDRNEL 400
>CCAMK_MEDTR (Q6RET7) Calcium and calcium/calmodulin-dependent| serine/threonine-protein kinase DMI-3 (EC 2.7.11.17) (Does not make infections protein 3) (CCaMK DMI3) (MtCCaMK) Length = 523 Score = 136 bits (342), Expect = 5e-32 Identities = 84/219 (38%), Positives = 120/219 (54%), Gaps = 20/219 (9%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKR-RYGAEADIWSA 178 EN LFL+ R+DSPLK DFGLS + + L GS YV+PE L + + ++D+WS Sbjct: 175 ENCLFLDVRKDSPLKIMDFGLSSVEEFTDPVVGLFGSIDYVSPEALSQGKITTKSDMWSL 234 Query: 179 GVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKER 358 GVILYILLSG PPF A+N ++ G+ F W IS AK+L+ +L DP +R Sbjct: 235 GVILYILLSGYPPFIAQNNRQKQQMIMNGNFSFYEKTWKGISQPAKNLISSLLTVDPSKR 294 Query: 359 LTAAEILNHPWIREDGEAPDKPLDITVISRMKQFRAMNKLKKVALKIVAES--------- 511 +A E+L+ PW++ + +A D +D ++SR++ F A KL+ A+ V S Sbjct: 295 PSALELLSDPWVKGE-KAKDVQMDPEIVSRLQSFNARRKLRAAAIASVWSSTIFLRTKKL 353 Query: 512 --------LSEEEIVGLREMFKSL--DTDNSGTITLDEL 598 L EEEI LR FK + D DN+ +E+ Sbjct: 354 KSLVGSYDLKEEEIENLRMHFKKICADRDNATLSEFEEV 392
>CDPK4_PLAF7 (Q8IBS5) Calcium-dependent protein kinase 4 (EC 2.7.11.1)| Length = 527 Score = 135 bits (339), Expect = 1e-31 Identities = 80/205 (39%), Positives = 115/205 (56%), Gaps = 6/205 (2%) Frame = +2 Query: 2 ENFLFLNK-REDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRRYGAEADIWSA 178 EN L K +ED +K DFGLS F+ ++ +D +G+AYY+AP+VL Y + DIWS Sbjct: 196 ENILLETKNKEDMIIKIIDFGLSTHFEYSKKMKDKIGTAYYIAPDVLHGTYDEKCDIWSC 255 Query: 179 GVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKER 358 GVILYILLSG PPF NE I V G F + IS+ AKDL+K+ML R Sbjct: 256 GVILYILLSGCPPFNGSNEYDILKKVEAGKYTFDLPQFKKISDKAKDLIKKMLMYTSAVR 315 Query: 359 LTAAEILNHPWIR----EDGEAPDKPLDITVISRMKQFRAMNKLKKVALKIVAESLSE-E 523 ++A + L H WI+ +D D P I+ ++QF++ KL + AL + L+ + Sbjct: 316 ISARDALEHEWIKMMTSKDNLNIDIPSLELSIANIRQFQSTQKLAQAALLYMGSKLTTID 375 Query: 524 EIVGLREMFKSLDTDNSGTITLDEL 598 E L ++FK +D + G + +EL Sbjct: 376 ETKELTKIFKKMDKNGDGQLDRNEL 400
>CCAMK_PEA (Q6RET6) Calcium and calcium/calmodulin-dependent| serine/threonine-protein kinase (EC 2.7.11.17) (PsCCaMK) (Ps-SYM9) (Fragment) Length = 527 Score = 131 bits (330), Expect = 1e-30 Identities = 82/219 (37%), Positives = 119/219 (54%), Gaps = 20/219 (9%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKR-RYGAEADIWSA 178 EN LFL+ +DS LK DFGLS + + L GS YV+PE L + + ++D+WS Sbjct: 183 ENCLFLDVGKDSSLKIMDFGLSSVEEFTDPVVGLFGSIDYVSPEALSQGKITTKSDMWSL 242 Query: 179 GVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKER 358 GVILYILLSG PPF A+N +L G+ F W IS AK+L+ +L DP +R Sbjct: 243 GVILYILLSGYPPFIAQNNRQKQQMILNGNFSFYEKTWKGISQSAKNLISSLLTVDPAKR 302 Query: 359 LTAAEILNHPWIREDGEAPDKPLDITVISRMKQFRAMNKLKKVALKIVAES--------- 511 +A E+L+ PW++ + +A D +D ++SR+++F A KL+ A+ V S Sbjct: 303 PSAQELLSDPWVKGE-KAKDDQMDPEIVSRLQRFNARRKLRAAAIASVWSSTIFLRTKKL 361 Query: 512 --------LSEEEIVGLREMFKSL--DTDNSGTITLDEL 598 L E+EI LR FK + D DN+ +E+ Sbjct: 362 KSLVGSYDLKEDEIENLRMHFKKICADRDNATLCEFEEV 400
>KCC1A_HUMAN (Q14012) Calcium/calmodulin-dependent protein kinase type 1 (EC| 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha) Length = 370 Score = 128 bits (321), Expect = 1e-29 Identities = 67/162 (41%), Positives = 96/162 (59%), Gaps = 1/162 (0%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRR-YGAEADIWSA 178 EN L+ + EDS + +DFGLS PG G+ YVAPEVL ++ Y D WS Sbjct: 145 ENLLYYSLDEDSKIMISDFGLSKMEDPGSVLSTACGTPGYVAPEVLAQKPYSKAVDCWSI 204 Query: 179 GVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKER 358 GVI YILL G PPF+ EN+ +F+ +LK +F S W IS+ AKD ++ ++ +DP++R Sbjct: 205 GVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDFIRHLMEKDPEKR 264 Query: 359 LTAAEILNHPWIREDGEAPDKPLDITVISRMKQFRAMNKLKK 484 T + L HPWI D A DK + +V ++K+ A +K K+ Sbjct: 265 FTCEQALQHPWIAGD-TALDKNIHQSVSEQIKKNFAKSKWKQ 305
>KCC1A_RAT (Q63450) Calcium/calmodulin-dependent protein kinase type 1 (EC| 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha) Length = 374 Score = 128 bits (321), Expect = 1e-29 Identities = 67/162 (41%), Positives = 96/162 (59%), Gaps = 1/162 (0%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRR-YGAEADIWSA 178 EN L+ + EDS + +DFGLS PG G+ YVAPEVL ++ Y D WS Sbjct: 145 ENLLYYSLDEDSKIMISDFGLSKMEDPGSVLSTACGTPGYVAPEVLAQKPYSKAVDCWSI 204 Query: 179 GVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKER 358 GVI YILL G PPF+ EN+ +F+ +LK +F S W IS+ AKD ++ ++ +DP++R Sbjct: 205 GVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDFIRHLMEKDPEKR 264 Query: 359 LTAAEILNHPWIREDGEAPDKPLDITVISRMKQFRAMNKLKK 484 T + L HPWI D A DK + +V ++K+ A +K K+ Sbjct: 265 FTCEQALQHPWIAGD-TALDKNIHQSVSEQIKKNFAKSKWKQ 305
>KCC1A_MOUSE (Q91YS8) Calcium/calmodulin-dependent protein kinase type 1 (EC| 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha) Length = 374 Score = 128 bits (321), Expect = 1e-29 Identities = 67/162 (41%), Positives = 96/162 (59%), Gaps = 1/162 (0%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRR-YGAEADIWSA 178 EN L+ + EDS + +DFGLS PG G+ YVAPEVL ++ Y D WS Sbjct: 145 ENLLYYSLDEDSKIMISDFGLSKMEDPGSVLSTACGTPGYVAPEVLAQKPYSKAVDCWSI 204 Query: 179 GVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKER 358 GVI YILL G PPF+ EN+ +F+ +LK +F S W IS+ AKD ++ ++ +DP++R Sbjct: 205 GVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDFIRHLMEKDPEKR 264 Query: 359 LTAAEILNHPWIREDGEAPDKPLDITVISRMKQFRAMNKLKK 484 T + L HPWI D A DK + +V ++K+ A +K K+ Sbjct: 265 FTCEQALQHPWIAGD-TALDKNIHQSVSEQIKKNFAKSKWKQ 305
>CCAMK_LILLO (Q43531) Calcium and calcium/calmodulin-dependent| serine/threonine-protein kinase (EC 2.7.11.17) (LlCCaMK) Length = 520 Score = 126 bits (317), Expect = 4e-29 Identities = 82/216 (37%), Positives = 111/216 (51%), Gaps = 18/216 (8%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRRYGAEA-DIWSA 178 EN LFLN+ + S LK DFGLS + L GS YV+PE L +R + A D+WS Sbjct: 171 ENCLFLNQEKRSTLKIMDFGLSSVEDFTDPIVALFGSIDYVSPEALSQRQVSSASDMWSL 230 Query: 179 GVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKER 358 GVILYILLSG PPF A + +L G F W +I++ AKDL+ +L DP +R Sbjct: 231 GVILYILLSGCPPFHAPSNREKQQRILAGDFSFEEHTWKTITSSAKDLISSLLSVDPYKR 290 Query: 359 LTAAEILNHPWIREDGEAPDKPLDITVISRMKQFRAMNKLKKVALKIVAES--------- 511 TA ++L HPW+ D A + ++ V+SR++ F A KL+ A+ V S Sbjct: 291 PTANDLLKHPWVIGD-SAKQELIEPEVVSRLRSFNARRKLRAAAIASVLSSKVLLRTKKL 349 Query: 512 --------LSEEEIVGLREMFKSLDTDNSGTITLDE 595 + EE+ LR FK + N TL E Sbjct: 350 KNLLGSHDMKSEELENLRAHFKRI-CANGDNATLPE 384
>KCC2D_HUMAN (Q13557) Calcium/calmodulin-dependent protein kinase type II delta| chain (EC 2.7.11.17) (CaM-kinase II delta chain) (CaM kinase II delta subunit) (CaMK-II delta subunit) Length = 499 Score = 122 bits (307), Expect = 6e-28 Identities = 70/205 (34%), Positives = 110/205 (53%), Gaps = 7/205 (3%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQ-FRDLVGSAYYVAPEVLKRR-YGAEADIWS 175 EN L +K + + +K DFGL++ + +Q + G+ Y++PEVL++ YG D+W+ Sbjct: 140 ENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWA 199 Query: 176 AGVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKE 355 GVILYILL G PPFW E++ ++ + G DF S W +++ AKDL+ +ML +P + Sbjct: 200 CGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAK 259 Query: 356 RLTAAEILNHPWIREDGEAPDKPLDITVISRMKQFRAMNKLKKVALKIVAESLSEEEIVG 535 R+TA+E L HPWI + + +K+F A KLK I+ L+ Sbjct: 260 RITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKLKGA---ILTTMLATRNFSA 316 Query: 536 LREMFKSLD-----TDNSGTITLDE 595 + + K D T++S T DE Sbjct: 317 AKSLLKKPDGVKESTESSNTTIEDE 341
>KPSH1_BRARE (Q501V0) Serine/threonine-protein kinase H1 homolog (EC 2.7.11.1)| Length = 422 Score = 121 bits (304), Expect = 1e-27 Identities = 61/134 (45%), Positives = 84/134 (62%), Gaps = 3/134 (2%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQ--FRDLVGSAYYVAPEVLKRR-YGAEADIW 172 EN L+ + DS + TDFGL+ K G++ + G+ Y+APE+L R+ Y D+W Sbjct: 220 ENLLYYHPGADSKIMITDFGLASTRKKGDECLMKTTCGTPEYIAPEILVRKPYTNAVDMW 279 Query: 173 SAGVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPK 352 + GVI YILLSG PF +N ++ +LKG FS +PWPS+SN AKD + R+L DP Sbjct: 280 ALGVISYILLSGTMPFEDDNRMRLYRQILKGKYSFSGEPWPSVSNLAKDFIDRVLTVDPN 339 Query: 353 ERLTAAEILNHPWI 394 ERL+A + L HPWI Sbjct: 340 ERLSAGQALKHPWI 353
>KCC2A_DROME (Q00168) Calcium/calmodulin-dependent protein kinase type II alpha| chain (EC 2.7.11.17) (CaM-kinase II alpha chain) Length = 530 Score = 120 bits (302), Expect = 2e-27 Identities = 63/166 (37%), Positives = 95/166 (57%), Gaps = 2/166 (1%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQ-FRDLVGSAYYVAPEVLKRR-YGAEADIWS 175 EN L +K + + +K DFGL++ + Q + G+ Y++PEVLK+ YG DIW+ Sbjct: 140 ENLLLASKAKGAAVKLADFGLAIEVQGDHQAWFGFAGTPGYLSPEVLKKEPYGKSVDIWA 199 Query: 176 AGVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKE 355 GVILYILL G PPFW E++ ++ + G D+ S W +++ AK+L+ +ML +P + Sbjct: 200 CGVILYILLVGYPPFWDEDQHRLYSQIKAGAYDYPSPEWDTVTPEAKNLINQMLTVNPNK 259 Query: 356 RLTAAEILNHPWIREDGEAPDKPLDITVISRMKQFRAMNKLKKVAL 493 R+TAAE L HPWI + + +K+F A KLK L Sbjct: 260 RITAAEALKHPWICQRERVASVVHRQETVDCLKKFNARRKLKGAIL 305
>KCC2A_RAT (P11275) Calcium/calmodulin-dependent protein kinase type II alpha| chain (EC 2.7.11.17) (CaM-kinase II alpha chain) (CaM kinase II alpha subunit) (CaMK-II alpha subunit) Length = 478 Score = 120 bits (302), Expect = 2e-27 Identities = 63/166 (37%), Positives = 95/166 (57%), Gaps = 2/166 (1%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQ-FRDLVGSAYYVAPEVLKRR-YGAEADIWS 175 EN L +K + + +K DFGL++ + +Q + G+ Y++PEVL++ YG D+W+ Sbjct: 139 ENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDLWA 198 Query: 176 AGVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKE 355 GVILYILL G PPFW E++ ++ + G DF S W +++ AKDL+ +ML +P + Sbjct: 199 CGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSK 258 Query: 356 RLTAAEILNHPWIREDGEAPDKPLDITVISRMKQFRAMNKLKKVAL 493 R+TAAE L HPWI + +K+F A KLK L Sbjct: 259 RITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLKGAIL 304
>KCC2A_PONPY (Q5RCC4) Calcium/calmodulin-dependent protein kinase type II alpha| chain (EC 2.7.11.17) (CaM-kinase II alpha chain) (CaM kinase II alpha subunit) (CaMK-II alpha subunit) Length = 478 Score = 120 bits (302), Expect = 2e-27 Identities = 63/166 (37%), Positives = 95/166 (57%), Gaps = 2/166 (1%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQ-FRDLVGSAYYVAPEVLKRR-YGAEADIWS 175 EN L +K + + +K DFGL++ + +Q + G+ Y++PEVL++ YG D+W+ Sbjct: 139 ENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDLWA 198 Query: 176 AGVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKE 355 GVILYILL G PPFW E++ ++ + G DF S W +++ AKDL+ +ML +P + Sbjct: 199 CGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSK 258 Query: 356 RLTAAEILNHPWIREDGEAPDKPLDITVISRMKQFRAMNKLKKVAL 493 R+TAAE L HPWI + +K+F A KLK L Sbjct: 259 RITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLKGAIL 304
>KCC2A_HUMAN (Q9UQM7) Calcium/calmodulin-dependent protein kinase type II alpha| chain (EC 2.7.11.17) (CaM-kinase II alpha chain) (CaM kinase II alpha subunit) (CaMK-II alpha subunit) Length = 478 Score = 120 bits (302), Expect = 2e-27 Identities = 63/166 (37%), Positives = 95/166 (57%), Gaps = 2/166 (1%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQ-FRDLVGSAYYVAPEVLKRR-YGAEADIWS 175 EN L +K + + +K DFGL++ + +Q + G+ Y++PEVL++ YG D+W+ Sbjct: 139 ENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDLWA 198 Query: 176 AGVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKE 355 GVILYILL G PPFW E++ ++ + G DF S W +++ AKDL+ +ML +P + Sbjct: 199 CGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSK 258 Query: 356 RLTAAEILNHPWIREDGEAPDKPLDITVISRMKQFRAMNKLKKVAL 493 R+TAAE L HPWI + +K+F A KLK L Sbjct: 259 RITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLKGAIL 304
>KCC2D_RAT (P15791) Calcium/calmodulin-dependent protein kinase type II delta| chain (EC 2.7.11.17) (CaM-kinase II delta chain) (CaM kinase II delta subunit) (CaMK-II delta subunit) Length = 533 Score = 120 bits (301), Expect = 3e-27 Identities = 62/166 (37%), Positives = 96/166 (57%), Gaps = 2/166 (1%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQ-FRDLVGSAYYVAPEVLKRR-YGAEADIWS 175 EN L +K + + +K DFGL++ + +Q + G+ Y++PEVL++ YG D+W+ Sbjct: 140 ENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWA 199 Query: 176 AGVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKE 355 GVILYILL G PPFW E++ ++ + G DF S W +++ AKDL+ +ML +P + Sbjct: 200 CGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAK 259 Query: 356 RLTAAEILNHPWIREDGEAPDKPLDITVISRMKQFRAMNKLKKVAL 493 R+TA+E L HPWI + + +K+F A KLK L Sbjct: 260 RITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKLKGAIL 305
>KCC2A_MOUSE (P11798) Calcium/calmodulin-dependent protein kinase type II alpha| chain (EC 2.7.11.17) (CaM-kinase II alpha chain) (CaM kinase II alpha subunit) (CaMK-II alpha subunit) Length = 478 Score = 119 bits (298), Expect = 7e-27 Identities = 65/167 (38%), Positives = 95/167 (56%), Gaps = 3/167 (1%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFR--DLVGSAYYVAPEVLKRR-YGAEADIW 172 EN L +K + + +K DFGL++ + GEQ R G+ Y++PEVL++ YG D+W Sbjct: 139 ENLLLASKLKGAAVKLADFGLAIEVE-GEQQRWFGFAGTPGYLSPEVLRKDPYGKPVDLW 197 Query: 173 SAGVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPK 352 + GVILYILL G PPFW E++ ++ + DF S W +++ AKDL+ +ML +P Sbjct: 198 ACGVILYILLVGYPPFWDEDQHRLYQQIKARAYDFPSPEWDTVTPEAKDLINKMLTINPS 257 Query: 353 ERLTAAEILNHPWIREDGEAPDKPLDITVISRMKQFRAMNKLKKVAL 493 +R+TAAE L HPWI + +K+F A KLK L Sbjct: 258 KRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLKGAIL 304
>KCC1D_HUMAN (Q8IU85) Calcium/calmodulin-dependent protein kinase type 1D (EC| 2.7.11.17) (CaM kinase ID) (CaM kinase I delta) (CaMKI-delta) (CaM-KI delta) (CaMKI delta) (Camk1D) (CamKI-like protein kinase) (CKLiK) Length = 385 Score = 119 bits (297), Expect = 9e-27 Identities = 61/162 (37%), Positives = 96/162 (59%), Gaps = 1/162 (0%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRR-YGAEADIWSA 178 EN L+ ++ E+S + +DFGLS G+ G+ YVAPEVL ++ Y D WS Sbjct: 148 ENLLYYSQDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAPEVLAQKPYSKAVDCWSI 207 Query: 179 GVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKER 358 GVI YILL G PPF+ EN+ +F+ +LK +F S W IS+ AKD ++ ++ +DP +R Sbjct: 208 GVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLMEKDPNKR 267 Query: 359 LTAAEILNHPWIREDGEAPDKPLDITVISRMKQFRAMNKLKK 484 T + HPWI D A +K + +V +++++ A +K ++ Sbjct: 268 YTCEQAARHPWIAGD-TALNKNIHESVSAQIRKNFAKSKWRQ 308
>KCC1D_MOUSE (Q8BW96) Calcium/calmodulin-dependent protein kinase type 1D (EC| 2.7.11.17) (CaM kinase ID) (CaM kinase I delta) (CaMKI-delta) (CaM-KI delta) (CaMKI delta) (Camk1D) (CamKI-like protein kinase) (CKLiK) (mCKLiK) Length = 385 Score = 118 bits (296), Expect = 1e-26 Identities = 61/162 (37%), Positives = 95/162 (58%), Gaps = 1/162 (0%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRR-YGAEADIWSA 178 EN L+ ++ E+S + +DFGLS G+ G+ YVAPEVL ++ Y D WS Sbjct: 148 ENLLYYSQDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAPEVLAQKPYSKAVDCWSI 207 Query: 179 GVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKER 358 GVI YILL G PPF+ EN+ +F+ +LK +F S W IS+ AKD ++ ++ +DP +R Sbjct: 208 GVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLMEKDPNKR 267 Query: 359 LTAAEILNHPWIREDGEAPDKPLDITVISRMKQFRAMNKLKK 484 T + HPWI D A K + +V +++++ A +K ++ Sbjct: 268 YTCEQAARHPWIAGD-TALSKNIHESVSAQIRKNFAKSKWRQ 308
>CSKP_RAT (Q62915) Peripheral plasma membrane protein CASK (EC 2.7.11.1)| (Calcium/calmodulin-dependent serine protein kinase) Length = 909 Score = 118 bits (295), Expect = 1e-26 Identities = 65/167 (38%), Positives = 95/167 (56%), Gaps = 2/167 (1%) Frame = +2 Query: 11 LFLNKREDSPLKATDFGLSVFF-KPGEQFRDLVGSAYYVAPEVLKRR-YGAEADIWSAGV 184 L +K +P+K FG+++ + G VG+ +++APEV+KR YG D+W GV Sbjct: 148 LLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMAPEVVKREPYGKPVDVWGCGV 207 Query: 185 ILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLT 364 IL+ILLSG PF+ E +F+ ++KG + W IS AKDLV+RML DP ER+T Sbjct: 208 ILFILLSGCLPFYGTKER-LFEGIIKGKYKMNPRQWSHISESAKDLVRRMLMLDPAERIT 266 Query: 365 AAEILNHPWIREDGEAPDKPLDITVISRMKQFRAMNKLKKVALKIVA 505 E LNHPW++E K + ++++F A KLK L V+ Sbjct: 267 VYEALNHPWLKERDRYAYKIHLPETVEQLRKFNARRKLKGAVLAAVS 313
>CSKP_HUMAN (O14936) Peripheral plasma membrane protein CASK (EC 2.7.11.1)| (hCASK) (Calcium/calmodulin-dependent serine protein kinase) (Lin-2 homolog) Length = 926 Score = 118 bits (295), Expect = 1e-26 Identities = 65/167 (38%), Positives = 95/167 (56%), Gaps = 2/167 (1%) Frame = +2 Query: 11 LFLNKREDSPLKATDFGLSVFF-KPGEQFRDLVGSAYYVAPEVLKRR-YGAEADIWSAGV 184 L +K +P+K FG+++ + G VG+ +++APEV+KR YG D+W GV Sbjct: 148 LLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMAPEVVKREPYGKPVDVWGCGV 207 Query: 185 ILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLT 364 IL+ILLSG PF+ E +F+ ++KG + W IS AKDLV+RML DP ER+T Sbjct: 208 ILFILLSGCLPFYGTKER-LFEGIIKGKYKMNPRQWSHISESAKDLVRRMLMLDPAERIT 266 Query: 365 AAEILNHPWIREDGEAPDKPLDITVISRMKQFRAMNKLKKVALKIVA 505 E LNHPW++E K + ++++F A KLK L V+ Sbjct: 267 VYEALNHPWLKERDRYAYKIHLPETVEQLRKFNARRKLKGAVLAAVS 313
>KCC2B_RAT (P08413) Calcium/calmodulin-dependent protein kinase type II beta| chain (EC 2.7.11.17) (CaM-kinase II beta chain) (CaM kinase II beta subunit) (CaMK-II beta subunit) Length = 542 Score = 117 bits (294), Expect = 2e-26 Identities = 61/166 (36%), Positives = 95/166 (57%), Gaps = 2/166 (1%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQ-FRDLVGSAYYVAPEVLKRR-YGAEADIWS 175 EN L +K + + +K DFGL++ + +Q + G+ Y++PEVL++ YG DIW+ Sbjct: 140 ENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEAYGKPVDIWA 199 Query: 176 AGVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKE 355 GVILYILL G PPFW E++ ++ + G DF S W +++ AK+L+ +ML +P + Sbjct: 200 CGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAK 259 Query: 356 RLTAAEILNHPWIREDGEAPDKPLDITVISRMKQFRAMNKLKKVAL 493 R+TA E L HPW+ + + +K+F A KLK L Sbjct: 260 RITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKGAIL 305
>KCC2B_MOUSE (P28652) Calcium/calmodulin-dependent protein kinase type II beta| chain (EC 2.7.11.17) (CaM-kinase II beta chain) (CaM kinase II beta subunit) (CaMK-II beta subunit) Length = 542 Score = 117 bits (294), Expect = 2e-26 Identities = 61/166 (36%), Positives = 95/166 (57%), Gaps = 2/166 (1%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQ-FRDLVGSAYYVAPEVLKRR-YGAEADIWS 175 EN L +K + + +K DFGL++ + +Q + G+ Y++PEVL++ YG DIW+ Sbjct: 140 ENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEAYGKPVDIWA 199 Query: 176 AGVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKE 355 GVILYILL G PPFW E++ ++ + G DF S W +++ AK+L+ +ML +P + Sbjct: 200 CGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAK 259 Query: 356 RLTAAEILNHPWIREDGEAPDKPLDITVISRMKQFRAMNKLKKVAL 493 R+TA E L HPW+ + + +K+F A KLK L Sbjct: 260 RITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKGAIL 305
>KCC2B_HUMAN (Q13554) Calcium/calmodulin-dependent protein kinase type II beta| chain (EC 2.7.11.17) (CaM-kinase II beta chain) (CaM kinase II beta subunit) (CaMK-II beta subunit) Length = 664 Score = 117 bits (294), Expect = 2e-26 Identities = 61/166 (36%), Positives = 95/166 (57%), Gaps = 2/166 (1%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQ-FRDLVGSAYYVAPEVLKRR-YGAEADIWS 175 EN L +K + + +K DFGL++ + +Q + G+ Y++PEVL++ YG DIW+ Sbjct: 140 ENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEAYGKPVDIWA 199 Query: 176 AGVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKE 355 GVILYILL G PPFW E++ ++ + G DF S W +++ AK+L+ +ML +P + Sbjct: 200 CGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAK 259 Query: 356 RLTAAEILNHPWIREDGEAPDKPLDITVISRMKQFRAMNKLKKVAL 493 R+TA E L HPW+ + + +K+F A KLK L Sbjct: 260 RITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKGAIL 305
>KCC4_MOUSE (P08414) Calcium/calmodulin-dependent protein kinase type IV (EC| 2.7.11.17) (CAM kinase-GR) (CaMK IV) Length = 469 Score = 117 bits (293), Expect = 3e-26 Identities = 67/172 (38%), Positives = 96/172 (55%), Gaps = 2/172 (1%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKR-RYGAEADIWSA 178 EN L+ D+PLK DFGLS + + + G+ Y APE+L+ YG E D+WS Sbjct: 164 ENLLYATPAPDAPLKIADFGLSKIVEHQVLMKTVCGTPGYCAPEILRGCAYGPEVDMWSV 223 Query: 179 GVILYILLSGVPPFWAEN-EEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKE 355 G+I YILL G PF+ E ++ +F +L F S W +S AKDLVK+++ DPK+ Sbjct: 224 GIITYILLCGFEPFYDERGDQFMFRRILNCEYYFISPWWDEVSLNAKDLVKKLIVLDPKK 283 Query: 356 RLTAAEILNHPWIREDGEAPDKPLDITVISRMKQFRAMNKLKKVALKIVAES 511 RLT + L HPW+ G+A + T ++++F A KLK +VA S Sbjct: 284 RLTTFQALQHPWV--TGKAANFVHMDTAQKKLQEFNARRKLKAAVKAVVASS 333
>KCC4_RAT (P13234) Calcium/calmodulin-dependent protein kinase type IV (EC| 2.7.11.17) (CAM kinase-GR) (CaMK IV) (Calspermin) Length = 474 Score = 117 bits (293), Expect = 3e-26 Identities = 67/172 (38%), Positives = 96/172 (55%), Gaps = 2/172 (1%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKR-RYGAEADIWSA 178 EN L+ D+PLK DFGLS + + + G+ Y APE+L+ YG E D+WS Sbjct: 164 ENLLYATPAPDAPLKIADFGLSKIVEHQVLMKTVCGTPGYCAPEILRGCAYGPEVDMWSV 223 Query: 179 GVILYILLSGVPPFWAEN-EEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKE 355 G+I YILL G PF+ E ++ +F +L F S W +S AKDLVK+++ DPK+ Sbjct: 224 GIITYILLCGFEPFYDERGDQFMFRRILNCEYYFISPWWDEVSLNAKDLVKKLIVLDPKK 283 Query: 356 RLTAAEILNHPWIREDGEAPDKPLDITVISRMKQFRAMNKLKKVALKIVAES 511 RLT + L HPW+ G+A + T ++++F A KLK +VA S Sbjct: 284 RLTTFQALQHPWV--TGKAANFVHMDTAQKKLQEFNARRKLKAAVKAVVASS 333
>KPSH1_HUMAN (P11801) Serine/threonine-protein kinase H1 (EC 2.7.11.1) (PSK-H1)| Length = 423 Score = 116 bits (291), Expect = 4e-26 Identities = 58/134 (43%), Positives = 82/134 (61%), Gaps = 3/134 (2%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQ--FRDLVGSAYYVAPEVLKRR-YGAEADIW 172 EN L+ + DS + TDFGL+ K G+ + G+ Y+APEVL R+ Y D+W Sbjct: 221 ENLLYYHPGTDSKIIITDFGLASARKKGDDCLMKTTCGTPEYIAPEVLVRKPYTNSVDMW 280 Query: 173 SAGVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPK 352 + GVI YILLSG PF +N ++ +L+G +S +PWPS+SN AKD + R+L DP Sbjct: 281 ALGVIAYILLSGTMPFEDDNRTRLYRQILRGKYSYSGEPWPSVSNLAKDFIDRLLTVDPG 340 Query: 353 ERLTAAEILNHPWI 394 R+TA + L HPW+ Sbjct: 341 ARMTALQALRHPWV 354
>KCC4_HUMAN (Q16566) Calcium/calmodulin-dependent protein kinase type IV (EC| 2.7.11.17) (CAM kinase-GR) (CaMK IV) Length = 473 Score = 116 bits (290), Expect = 6e-26 Identities = 66/172 (38%), Positives = 96/172 (55%), Gaps = 2/172 (1%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKR-RYGAEADIWSA 178 EN L+ D+PLK DFGLS + + + G+ Y APE+L+ YG E D+WS Sbjct: 168 ENLLYATPAPDAPLKIADFGLSKIVEHQVLMKTVCGTPGYCAPEILRGCAYGPEVDMWSV 227 Query: 179 GVILYILLSGVPPFWAEN-EEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKE 355 G+I YILL G PF+ E ++ +F +L F S W +S AKDLV++++ DPK+ Sbjct: 228 GIITYILLCGFEPFYDERGDQFMFRRILNCEYYFISPWWDEVSLNAKDLVRKLIVLDPKK 287 Query: 356 RLTAAEILNHPWIREDGEAPDKPLDITVISRMKQFRAMNKLKKVALKIVAES 511 RLT + L HPW+ G+A + T ++++F A KLK +VA S Sbjct: 288 RLTTFQALQHPWV--TGKAANFVHMDTAQKKLQEFNARRKLKAAVKAVVASS 337
>CSKP_MOUSE (O70589) Peripheral plasma membrane protein CASK (EC 2.7.11.1)| (Calcium/calmodulin-dependent serine protein kinase) Length = 924 Score = 115 bits (289), Expect = 7e-26 Identities = 64/167 (38%), Positives = 94/167 (56%), Gaps = 2/167 (1%) Frame = +2 Query: 11 LFLNKREDSPLKATDFGLSVFF-KPGEQFRDLVGSAYYVAPEVLKRR-YGAEADIWSAGV 184 L +K +P+K FG+++ + G VG+ +++APEV+KR YG D+W GV Sbjct: 148 LLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMAPEVVKREPYGKPVDVWGCGV 207 Query: 185 ILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLT 364 IL+ILLSG PF+ E +F+ ++KG + W IS AKDLV+RML DP ER+T Sbjct: 208 ILFILLSGCLPFYGTKER-LFEGIIKGKYKMNPRQWSHISESAKDLVRRMLMLDPAERIT 266 Query: 365 AAEILNHPWIREDGEAPDKPLDITVISRMKQFRAMNKLKKVALKIVA 505 E LNHPW++E K + ++++ A KLK L V+ Sbjct: 267 VYEALNHPWLKERDRYAYKIHLPETVEQLRKLNARRKLKGAVLAAVS 313
>KCCS_MALDO (Q07250) Calcium/calmodulin-dependent serine/threonine-protein| kinase (EC 2.7.11.17) Length = 415 Score = 114 bits (286), Expect = 2e-25 Identities = 64/168 (38%), Positives = 95/168 (56%), Gaps = 1/168 (0%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKR-RYGAEADIWSA 178 EN LFL+ DSPLK DFGLS + + L GS YV+PE L + + +++D+W+ Sbjct: 177 ENCLFLDNTVDSPLKIMDFGLSSVEEFTDPVVGLFGSIDYVSPEALSQGQVTSKSDMWAL 236 Query: 179 GVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKER 358 GVILYILLSG PPF A++ ++ G F W K L+ +L+ DP +R Sbjct: 237 GVILYILLSGYPPFIAQSNRQKQQMIMAGEFSFYEKTWKGFLCQPKQLISSLLKVDPDKR 296 Query: 359 LTAAEILNHPWIREDGEAPDKPLDITVISRMKQFRAMNKLKKVALKIV 502 +A E+L+HPW+ A + +D ++SR++ F A KL+ A+ V Sbjct: 297 PSAQELLDHPWV-VGLSAREDQMDAEIVSRLQSFNARRKLRAAAIASV 343
>KPSH1_MOUSE (Q91YA2) Serine/threonine-protein kinase H1 (EC 2.7.11.1) (PSK-H1)| Length = 423 Score = 114 bits (285), Expect = 2e-25 Identities = 57/134 (42%), Positives = 81/134 (60%), Gaps = 3/134 (2%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQ--FRDLVGSAYYVAPEVLKRR-YGAEADIW 172 EN L+ + DS + TDFGL+ K G+ + G+ Y+APEVL R+ Y D+W Sbjct: 221 ENLLYYHPGTDSKIIITDFGLASARKKGDDCLMKTTCGTPEYIAPEVLVRKPYTNSVDMW 280 Query: 173 SAGVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPK 352 + GVI YILLSG PF +N ++ +L+G + +PWPS+SN AKD + R+L DP Sbjct: 281 ALGVIAYILLSGTMPFEDDNRTRLYRQILRGKYSYLGEPWPSVSNLAKDFIDRLLTVDPG 340 Query: 353 ERLTAAEILNHPWI 394 R+TA + L HPW+ Sbjct: 341 ARMTALQALRHPWV 354
>KCC2G_HUMAN (Q13555) Calcium/calmodulin-dependent protein kinase type II gamma| chain (EC 2.7.11.17) (CaM-kinase II gamma chain) (CaM kinase II gamma subunit) (CaMK-II gamma subunit) Length = 558 Score = 114 bits (285), Expect = 2e-25 Identities = 59/166 (35%), Positives = 95/166 (57%), Gaps = 2/166 (1%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQ-FRDLVGSAYYVAPEVLKRR-YGAEADIWS 175 EN L +K + + +K DFGL++ + +Q + G+ Y++PEVL++ YG DIW+ Sbjct: 140 ENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDIWA 199 Query: 176 AGVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKE 355 GVILYILL G PPFW E++ ++ + G DF S W +++ AK+L+ +ML +P + Sbjct: 200 CGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAK 259 Query: 356 RLTAAEILNHPWIREDGEAPDKPLDITVISRMKQFRAMNKLKKVAL 493 R+TA + L HPW+ + + +++F A KLK L Sbjct: 260 RITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKLKGAIL 305
>KCC1G_RAT (Q7TNJ7) Calcium/calmodulin-dependent protein kinase type 1G (EC| 2.7.11.17) (CaM kinase IG) (CaM kinase I gamma) (CaMKI gamma) (CaMKI-gamma) (CaM-KI gamma) (CaMKIG) (CaMK-like CREB kinase III) (CLICK III) Length = 476 Score = 114 bits (285), Expect = 2e-25 Identities = 59/132 (44%), Positives = 77/132 (58%), Gaps = 1/132 (0%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRR-YGAEADIWSA 178 EN L+L E+S + TDFGLS + G G+ YVAPEVL ++ Y D WS Sbjct: 147 ENLLYLTPEENSKIMITDFGLSKMEQNGVM-STACGTPGYVAPEVLAQKPYSKAVDCWSI 205 Query: 179 GVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKER 358 GVI YILL G PPF+ E E +F+ + +G+ +F S W IS AKD + +L +DP ER Sbjct: 206 GVITYILLCGYPPFYEETESKLFEKIKEGYYEFESPFWDDISESAKDFICHLLEKDPNER 265 Query: 359 LTAAEILNHPWI 394 T + L HPWI Sbjct: 266 YTCEKALRHPWI 277
>KCC1G_HUMAN (Q96NX5) Calcium/calmodulin-dependent protein kinase type 1G (EC| 2.7.11.17) (CaM kinase IG) (CaM kinase I gamma) (CaMKI gamma) (CaMKI-gamma) (CaM-KI gamma) (CaMKIG) (CaMK-like CREB kinase III) (CLICK III) Length = 476 Score = 114 bits (285), Expect = 2e-25 Identities = 59/132 (44%), Positives = 78/132 (59%), Gaps = 1/132 (0%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRR-YGAEADIWSA 178 EN L+L E+S + TDFGLS + G G+ YVAPEVL ++ Y D WS Sbjct: 147 ENLLYLTPEENSKIMITDFGLSKMEQNGIM-STACGTPGYVAPEVLAQKPYSKAVDCWSI 205 Query: 179 GVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKER 358 GVI YILL G PPF+ E E +F+ + +G+ +F S W IS AKD + +L +DP ER Sbjct: 206 GVITYILLCGYPPFYEETESKLFEKIKEGYYEFESPFWDDISESAKDFICHLLEKDPNER 265 Query: 359 LTAAEILNHPWI 394 T + L+HPWI Sbjct: 266 YTCEKALSHPWI 277
>KCC1G_MOUSE (Q91VB2) Calcium/calmodulin-dependent protein kinase type 1G (EC| 2.7.11.17) (CaM kinase IG) (CaM kinase I gamma) (CaMKI gamma) (CaMKI-gamma) (CaM-KI gamma) (CaMKIG) (CaMK-like CREB kinase III) (CLICK III) Length = 477 Score = 114 bits (285), Expect = 2e-25 Identities = 59/132 (44%), Positives = 77/132 (58%), Gaps = 1/132 (0%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRR-YGAEADIWSA 178 EN L+L E+S + TDFGLS + G G+ YVAPEVL ++ Y D WS Sbjct: 147 ENLLYLTPEENSKIMITDFGLSKMEQNGVM-STACGTPGYVAPEVLAQKPYSKAVDCWSI 205 Query: 179 GVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKER 358 GVI YILL G PPF+ E E +F+ + +G+ +F S W IS AKD + +L +DP ER Sbjct: 206 GVITYILLCGYPPFYEETESKLFEKIKEGYYEFESPFWDDISESAKDFICHLLEKDPNER 265 Query: 359 LTAAEILNHPWI 394 T + L HPWI Sbjct: 266 YTCEKALRHPWI 277
>KCC2G_MOUSE (Q923T9) Calcium/calmodulin-dependent protein kinase type II gamma| chain (EC 2.7.11.17) (CaM-kinase II gamma chain) (CaM kinase II gamma subunit) (CaMK-II gamma subunit) Length = 529 Score = 114 bits (285), Expect = 2e-25 Identities = 59/166 (35%), Positives = 95/166 (57%), Gaps = 2/166 (1%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQ-FRDLVGSAYYVAPEVLKRR-YGAEADIWS 175 EN L +K + + +K DFGL++ + +Q + G+ Y++PEVL++ YG DIW+ Sbjct: 140 ENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDIWA 199 Query: 176 AGVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKE 355 GVILYILL G PPFW E++ ++ + G DF S W +++ AK+L+ +ML +P + Sbjct: 200 CGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAK 259 Query: 356 RLTAAEILNHPWIREDGEAPDKPLDITVISRMKQFRAMNKLKKVAL 493 R+TA + L HPW+ + + +++F A KLK L Sbjct: 260 RITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKLKGAIL 305
>KCC2G_RAT (P11730) Calcium/calmodulin-dependent protein kinase type II gamma| chain (EC 2.7.11.17) (CaM-kinase II gamma chain) (CaM kinase II gamma subunit) (CaMK-II gamma subunit) Length = 527 Score = 114 bits (285), Expect = 2e-25 Identities = 59/166 (35%), Positives = 95/166 (57%), Gaps = 2/166 (1%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQ-FRDLVGSAYYVAPEVLKRR-YGAEADIWS 175 EN L +K + + +K DFGL++ + +Q + G+ Y++PEVL++ YG DIW+ Sbjct: 140 ENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDIWA 199 Query: 176 AGVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKE 355 GVILYILL G PPFW E++ ++ + G DF S W +++ AK+L+ +ML +P + Sbjct: 200 CGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAK 259 Query: 356 RLTAAEILNHPWIREDGEAPDKPLDITVISRMKQFRAMNKLKKVAL 493 R+TA + L HPW+ + + +++F A KLK L Sbjct: 260 RITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKLKGAIL 305
>PHKG2_HUMAN (P15735) Phosphorylase b kinase gamma catalytic chain, testis/liver| isoform (EC 2.7.11.19) (PHK-gamma-T) (Phosphorylase kinase gamma subunit 2) (PSK-C3) Length = 406 Score = 112 bits (279), Expect = 1e-24 Identities = 55/137 (40%), Positives = 83/137 (60%), Gaps = 8/137 (5%) Frame = +2 Query: 29 EDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRR-------YGAEADIWSAGVI 187 ++ ++ +DFG S +PGE+ R+L G+ Y+APE+LK YG E D+W+ GVI Sbjct: 163 DNMQIRLSDFGFSCHLEPGEKLRELCGTPGYLAPEILKCSMDETHPGYGKEVDLWACGVI 222 Query: 188 LYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTA 367 L+ LL+G PPFW + + +++G FSS W S+ KDL+ R+L+ DP+ RLTA Sbjct: 223 LFTLLAGSPPFWHRRQILMLRMIMEGQYQFSSPEWDDRSSTVKDLISRLLQVDPEARLTA 282 Query: 368 AEILNHPWI-REDGEAP 415 + L HP+ R +G P Sbjct: 283 EQALQHPFFERCEGSQP 299
>PHKG1_RABIT (P00518) Phosphorylase b kinase gamma catalytic chain, skeletal| muscle isoform (EC 2.7.11.19) (Phosphorylase kinase gamma subunit 1) Length = 386 Score = 112 bits (279), Expect = 1e-24 Identities = 58/166 (34%), Positives = 88/166 (53%), Gaps = 7/166 (4%) Frame = +2 Query: 29 EDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRR-------YGAEADIWSAGVI 187 +D +K TDFG S PGE+ R++ G+ Y+APE+++ YG E D+WS GVI Sbjct: 159 DDMNIKLTDFGFSCQLDPGEKLREVCGTPSYLAPEIIECSMNDNHPGYGKEVDMWSTGVI 218 Query: 188 LYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTA 367 +Y LL+G PPFW + + ++ G+ F S W S+ KDLV R L P++R TA Sbjct: 219 MYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGSPEWDDYSDTVKDLVSRFLVVQPQKRYTA 278 Query: 368 AEILNHPWIREDGEAPDKPLDITVISRMKQFRAMNKLKKVALKIVA 505 E L HP+ ++ V+ ++ F K K + L ++A Sbjct: 279 EEALAHPFFQQ-----------YVVEEVRHFSPRGKFKVICLTVLA 313
>MAPK3_RAT (Q66H84) MAP kinase-activated protein kinase 3 (EC 2.7.11.1)| (MAPK-activated protein kinase 3) (MAPKAP kinase 3) (MAPKAPK-3) Length = 384 Score = 111 bits (278), Expect = 1e-24 Identities = 61/149 (40%), Positives = 83/149 (55%), Gaps = 7/149 (4%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQ--FRDLVGSAYYVAPEVL-KRRYGAEADIW 172 EN L+ +K +D+ LK TDFG F K Q + + YYVAPEVL +Y D+W Sbjct: 172 ENLLYTSKEKDAVLKLTDFG---FAKETTQNALQTPCYTPYYVAPEVLGPEKYDKSCDMW 228 Query: 173 SAGVILYILLSGVPPFWAENEEGIFDAVLK----GHIDFSSDPWPSISNGAKDLVKRMLR 340 S GVI+YILL G PPF++ + I + + G F W +S AK L++ +L+ Sbjct: 229 SLGVIMYILLCGFPPFYSNTGQAISPGMKRRIRLGQYGFPKPEWADVSEDAKQLIRLLLK 288 Query: 341 QDPKERLTAAEILNHPWIREDGEAPDKPL 427 DP ERLT + +NHPWI + E P PL Sbjct: 289 TDPTERLTIMQFMNHPWINQSMEVPQTPL 317
>KCC1B_RAT (O70150) Calcium/calmodulin-dependent protein kinase type 1B (EC| 2.7.11.17) (CaM kinase IB) (CaM kinase I beta) (CaMKI-beta) (CaM-KI beta) (Pregnancy up-regulated non-ubiquitously expressed CaM kinase homolog) Length = 343 Score = 111 bits (278), Expect = 1e-24 Identities = 55/135 (40%), Positives = 80/135 (59%), Gaps = 1/135 (0%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRR-YGAEADIWSA 178 EN L+ EDS + +DFGLS + G G+ YVAPE+L+++ YG D+W+ Sbjct: 140 ENLLYATPFEDSKIMVSDFGLSKI-QAGNMLGTACGTPGYVAPELLEQKPYGKAVDVWAL 198 Query: 179 GVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKER 358 GVI YILL G PPF+ E++ +F +L+ +F S W IS AKD ++ +L +DP++R Sbjct: 199 GVISYILLCGYPPFYDESDPELFSQILRASYEFDSPFWDDISESAKDFIRHLLERDPQKR 258 Query: 359 LTAAEILNHPWIRED 403 T + L H WI D Sbjct: 259 FTCQQALQHLWISGD 273
>KCC1B_MOUSE (Q9QYK9) Calcium/calmodulin-dependent protein kinase type 1B (EC| 2.7.11.17) (CaM kinase IB) (CaM kinase I beta) (CaMKI-beta) (CaM-KI beta) (Pregnancy up-regulated non-ubiquitously expressed CaM kinase homolog) Length = 343 Score = 111 bits (278), Expect = 1e-24 Identities = 55/135 (40%), Positives = 80/135 (59%), Gaps = 1/135 (0%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRR-YGAEADIWSA 178 EN L+ EDS + +DFGLS + G G+ YVAPE+L+++ YG D+W+ Sbjct: 140 ENLLYATPFEDSKIMVSDFGLSKI-QAGNMLGTACGTPGYVAPELLEQKPYGKAVDVWAL 198 Query: 179 GVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKER 358 GVI YILL G PPF+ E++ +F +L+ +F S W IS AKD ++ +L +DP++R Sbjct: 199 GVISYILLCGYPPFYDESDPELFSQILRASYEFDSPFWDDISESAKDFIRHLLERDPQKR 258 Query: 359 LTAAEILNHPWIRED 403 T + L H WI D Sbjct: 259 FTCQQALQHLWISGD 273
>KCC1B_HUMAN (Q6P2M8) Calcium/calmodulin-dependent protein kinase type 1B (EC| 2.7.11.17) (CaM kinase IB) (CaM kinase I beta) (CaMKI-beta) (CaM-KI beta) (Pregnancy up-regulated non-ubiquitously expressed CaM kinase) Length = 343 Score = 111 bits (278), Expect = 1e-24 Identities = 55/135 (40%), Positives = 80/135 (59%), Gaps = 1/135 (0%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRR-YGAEADIWSA 178 EN L+ EDS + +DFGLS + G G+ YVAPE+L+++ YG D+W+ Sbjct: 140 ENLLYATPFEDSKIMVSDFGLSKI-QAGNMLGTACGTPGYVAPELLEQKPYGKAVDVWAL 198 Query: 179 GVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKER 358 GVI YILL G PPF+ E++ +F +L+ +F S W IS AKD ++ +L +DP++R Sbjct: 199 GVISYILLCGYPPFYDESDPELFSQILRASYEFDSPFWDDISESAKDFIRHLLERDPQKR 258 Query: 359 LTAAEILNHPWIRED 403 T + L H WI D Sbjct: 259 FTCQQALRHLWISGD 273
>PHKG1_HUMAN (Q16816) Phosphorylase b kinase gamma catalytic chain, skeletal| muscle isoform (EC 2.7.11.19) (Phosphorylase kinase gamma subunit 1) Length = 386 Score = 110 bits (276), Expect = 2e-24 Identities = 57/162 (35%), Positives = 87/162 (53%), Gaps = 7/162 (4%) Frame = +2 Query: 41 LKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRR-------YGAEADIWSAGVILYIL 199 +K TDFG S +PGE+ R++ G+ Y+APE+++ YG E D+WS GVI+Y L Sbjct: 163 IKLTDFGFSCQLEPGERLREVCGTPSYLAPEIIECSMNEDHPGYGKEVDMWSTGVIMYTL 222 Query: 200 LSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEIL 379 L+G PPFW + + ++ G+ F S W S+ KDLV R L P+ R TA E L Sbjct: 223 LAGSPPFWHRKQMLMLRMIMSGNYQFGSPEWDDYSDTVKDLVSRFLVVQPQNRYTAEEAL 282 Query: 380 NHPWIREDGEAPDKPLDITVISRMKQFRAMNKLKKVALKIVA 505 HP+ ++ ++ ++ F K K +AL ++A Sbjct: 283 AHPFFQQ-----------YLVEEVRHFSPRGKFKVIALTVLA 313
>PHKG2_RAT (P31325) Phosphorylase b kinase gamma catalytic chain, testis/liver| isoform (EC 2.7.11.19) (PHK-gamma-T) (Phosphorylase kinase gamma subunit 2) Length = 406 Score = 110 bits (276), Expect = 2e-24 Identities = 52/128 (40%), Positives = 78/128 (60%), Gaps = 7/128 (5%) Frame = +2 Query: 29 EDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRR-------YGAEADIWSAGVI 187 ++ ++ +DFG S +PGE+ R+L G+ Y+APE+LK YG E D+W+ GVI Sbjct: 163 DNMQIRLSDFGFSCHLEPGEKLRELCGTPGYLAPEILKCSMDETHPGYGKEVDLWACGVI 222 Query: 188 LYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTA 367 L+ LL+G PPFW + + +++G FSS W SN KDL+ ++L+ DP RLTA Sbjct: 223 LFTLLAGSPPFWHRRQILMLRMIMEGQYQFSSPEWDDRSNTVKDLIAKLLQVDPNARLTA 282 Query: 368 AEILNHPW 391 + L HP+ Sbjct: 283 EQALQHPF 290
>DCAK1_HUMAN (O15075) Serine/threonine-protein kinase DCAMKL1 (EC 2.7.11.1)| (Doublecortin-like and CAM kinase-like 1) Length = 740 Score = 110 bits (274), Expect = 4e-24 Identities = 60/156 (38%), Positives = 92/156 (58%), Gaps = 4/156 (2%) Frame = +2 Query: 2 ENFLFLNKREDSP-LKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRR-YGAEADIWS 175 EN L ++ S LK DFGL+ + G+ YVAPE++ YG + DIW+ Sbjct: 515 ENLLVYEHQDGSKSLKLGDFGLATIVDG--PLYTVCGTPTYVAPEIIAETGYGLKVDIWA 572 Query: 176 AGVILYILLSGVPPFWA--ENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDP 349 AGVI YILL G PPF +++E +FD +L G +DF S W ++S+ AK+L+ ML D Sbjct: 573 AGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELITMMLLVDV 632 Query: 350 KERLTAAEILNHPWIREDGEAPDKPLDITVISRMKQ 457 +R +A ++L HPW+ +DG P+ ++V ++K+ Sbjct: 633 DQRFSAVQVLEHPWVNDDG-LPENEHQLSVAGKIKK 667
>MAPK3_BOVIN (Q3SYZ2) MAP kinase-activated protein kinase 3 (EC 2.7.11.1)| (MAPK-activated protein kinase 3) (MAPKAP kinase 3) (MAPKAPK-3) Length = 384 Score = 110 bits (274), Expect = 4e-24 Identities = 61/149 (40%), Positives = 83/149 (55%), Gaps = 7/149 (4%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQ--FRDLVGSAYYVAPEVL-KRRYGAEADIW 172 EN L+ +K +D+ LK TDFG F K Q + + YYVAPEVL +Y D+W Sbjct: 172 ENLLYTSKDKDAVLKLTDFG---FAKETTQNALQTPCYTPYYVAPEVLGPEKYDKSCDMW 228 Query: 173 SAGVILYILLSGVPPFWAENEEGIFDAVLK----GHIDFSSDPWPSISNGAKDLVKRMLR 340 S GVI+YILL G PPF++ + I + + G F S W +S AK L++ +L+ Sbjct: 229 SLGVIMYILLCGFPPFYSNTGQAISPGMKRRIRLGQYGFPSPEWSEVSEDAKQLIRLLLK 288 Query: 341 QDPKERLTAAEILNHPWIREDGEAPDKPL 427 DP ERLT + +NHPWI + P PL Sbjct: 289 TDPTERLTITQFMNHPWINQSMVVPQTPL 317
>MAPK3_HUMAN (Q16644) MAP kinase-activated protein kinase 3 (EC 2.7.11.1)| (MAPK-activated protein kinase 3) (MAPKAP kinase 3) (MAPKAPK-3) (Chromosome 3p kinase) (3pK) Length = 382 Score = 109 bits (273), Expect = 5e-24 Identities = 60/149 (40%), Positives = 83/149 (55%), Gaps = 7/149 (4%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQ--FRDLVGSAYYVAPEVL-KRRYGAEADIW 172 EN L+ +K +D+ LK TDFG F K Q + + YYVAPEVL +Y D+W Sbjct: 170 ENLLYTSKEKDAVLKLTDFG---FAKETTQNALQTPCYTPYYVAPEVLGPEKYDKSCDMW 226 Query: 173 SAGVILYILLSGVPPFWAENEEGIFDAVLK----GHIDFSSDPWPSISNGAKDLVKRMLR 340 S GVI+YILL G PPF++ + I + + G F + W +S AK L++ +L+ Sbjct: 227 SLGVIMYILLCGFPPFYSNTGQAISPGMKRRIRLGQYGFPNPEWSEVSEDAKQLIRLLLK 286 Query: 341 QDPKERLTAAEILNHPWIREDGEAPDKPL 427 DP ERLT + +NHPWI + P PL Sbjct: 287 TDPTERLTITQFMNHPWINQSMVVPQTPL 315
>PHKG1_RAT (P13286) Phosphorylase b kinase gamma catalytic chain, skeletal| muscle isoform (EC 2.7.11.19) (Phosphorylase kinase gamma subunit 1) Length = 387 Score = 109 bits (273), Expect = 5e-24 Identities = 57/162 (35%), Positives = 86/162 (53%), Gaps = 7/162 (4%) Frame = +2 Query: 41 LKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRR-------YGAEADIWSAGVILYIL 199 +K TDFG S +PGE+ R++ G+ Y+APE+++ YG E D+WS GVI+Y L Sbjct: 163 IKLTDFGFSCQLQPGEKLREVCGTPSYLAPEIIQCSMDEGHPGYGKEVDMWSTGVIMYTL 222 Query: 200 LSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEIL 379 L+G PPFW + + ++ G F S W S+ KDLV R L P++R +A E L Sbjct: 223 LAGSPPFWHRKQMLMLRMIMDGKYQFGSPEWDDYSDTVKDLVSRFLVVQPQDRCSAEEAL 282 Query: 380 NHPWIREDGEAPDKPLDITVISRMKQFRAMNKLKKVALKIVA 505 HP+ +E V+ ++ F K K + L ++A Sbjct: 283 AHPFFQE-----------YVVEEVRHFSPRGKFKVICLTVLA 313
>PHKG1_MOUSE (P07934) Phosphorylase b kinase gamma catalytic chain, skeletal| muscle isoform (EC 2.7.11.19) (Phosphorylase kinase gamma subunit 1) Length = 387 Score = 109 bits (273), Expect = 5e-24 Identities = 57/162 (35%), Positives = 86/162 (53%), Gaps = 7/162 (4%) Frame = +2 Query: 41 LKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRR-------YGAEADIWSAGVILYIL 199 +K TDFG S +PGE+ R++ G+ Y+APE+++ YG E D+WS GVI+Y L Sbjct: 163 IKLTDFGFSCQLQPGEKLREVCGTPSYLAPEIIQCSMDDGHPGYGKEVDMWSTGVIMYTL 222 Query: 200 LSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEIL 379 L+G PPFW + + ++ G F S W S+ KDLV R L P++R +A E L Sbjct: 223 LAGSPPFWHRKQMLMLRMIMDGKYQFGSPEWDDYSDTVKDLVSRFLVVQPQDRCSAEEAL 282 Query: 380 NHPWIREDGEAPDKPLDITVISRMKQFRAMNKLKKVALKIVA 505 HP+ +E V+ ++ F K K + L ++A Sbjct: 283 AHPFFQE-----------YVVEEVRHFSPRGKFKVICLTVLA 313
>PHKG2_MOUSE (Q9DB30) Phosphorylase b kinase gamma catalytic chain, testis/liver| isoform (EC 2.7.11.19) (PHK-gamma-T) (Phosphorylase kinase gamma subunit 2) Length = 406 Score = 109 bits (272), Expect = 7e-24 Identities = 53/137 (38%), Positives = 82/137 (59%), Gaps = 8/137 (5%) Frame = +2 Query: 29 EDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRR-------YGAEADIWSAGVI 187 ++ ++ +DFG S + GE+ R+L G+ Y+APE+LK YG E D+W+ GVI Sbjct: 163 DNMQIRLSDFGFSCHLEAGEKLRELCGTPGYLAPEILKCSMDETHPGYGKEVDLWACGVI 222 Query: 188 LYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTA 367 L+ LL+G PPFW + + +++G F+S W SN KDL+ ++L+ DP+ RLTA Sbjct: 223 LFTLLAGSPPFWHRRQILMLRMIMEGQYQFTSPEWDDCSNTVKDLISKLLQVDPEARLTA 282 Query: 368 AEILNHPWI-REDGEAP 415 + L HP+ R +G P Sbjct: 283 EQALQHPFFERCEGSQP 299
>MAPK3_MOUSE (Q3UMW7) MAP kinase-activated protein kinase 3 (EC 2.7.11.1)| (MAPK-activated protein kinase 3) (MAPKAP kinase 3) (MAPKAPK-3) Length = 384 Score = 108 bits (271), Expect = 9e-24 Identities = 60/149 (40%), Positives = 83/149 (55%), Gaps = 7/149 (4%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQ--FRDLVGSAYYVAPEVL-KRRYGAEADIW 172 EN L+ +K +D+ LK TDFG F K Q + + YYVAPEVL +Y D+W Sbjct: 172 ENLLYTSKEKDAVLKLTDFG---FAKETTQNALQTPCYTPYYVAPEVLGPEKYDKSCDMW 228 Query: 173 SAGVILYILLSGVPPFWAENEEGIFDAVLK----GHIDFSSDPWPSISNGAKDLVKRMLR 340 S GVI+YILL G PPF++ + I + + G F + W +S AK L++ +L+ Sbjct: 229 SLGVIMYILLCGFPPFYSNTGQAISPGMKRRIRLGQYSFPNPEWLDVSEDAKQLIRLLLK 288 Query: 341 QDPKERLTAAEILNHPWIREDGEAPDKPL 427 DP ERLT + +NHPWI + P PL Sbjct: 289 TDPTERLTIMQFMNHPWINQSMVVPQTPL 317
>DCAK1_MOUSE (Q9JLM8) Serine/threonine-protein kinase DCAMKL1 (EC 2.7.11.1)| (Doublecortin-like and CAM kinase-like 1) Length = 756 Score = 108 bits (270), Expect = 1e-23 Identities = 59/156 (37%), Positives = 92/156 (58%), Gaps = 4/156 (2%) Frame = +2 Query: 2 ENFLFLNKREDSP-LKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRR-YGAEADIWS 175 EN L ++ S LK DFGL+ + G+ YVAPE++ YG + DIW+ Sbjct: 531 ENLLVYEHQDGSKSLKLGDFGLATIVDG--PLYTVCGTPTYVAPEIIAETGYGLKVDIWA 588 Query: 176 AGVILYILLSGVPPFWA--ENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDP 349 AGVI YILL G PPF +++E +FD +L G +DF S W ++S+ AK+L+ ML + Sbjct: 589 AGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELINMMLLVNV 648 Query: 350 KERLTAAEILNHPWIREDGEAPDKPLDITVISRMKQ 457 +R +A ++L HPW+ +DG P+ ++V ++K+ Sbjct: 649 DQRFSAVQVLEHPWVNDDG-LPENEHQLSVAGKIKK 683
>DCAK1_RAT (O08875) Serine/threonine-protein kinase DCAMKL1 (EC 2.7.11.1)| (Doublecortin-like and CAM kinase-like 1) (Calcium/calmodulin-dependent protein kinase type I-like CPG16) Length = 433 Score = 108 bits (270), Expect = 1e-23 Identities = 59/156 (37%), Positives = 92/156 (58%), Gaps = 4/156 (2%) Frame = +2 Query: 2 ENFLFLNKREDSP-LKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRR-YGAEADIWS 175 EN L ++ S LK DFGL+ + G+ YVAPE++ YG + DIW+ Sbjct: 208 ENLLVYEHQDGSKSLKLGDFGLATIVDG--PLYTVCGTPTYVAPEIIAETGYGLKVDIWA 265 Query: 176 AGVILYILLSGVPPFWA--ENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDP 349 AGVI YILL G PPF +++E +FD +L G +DF S W ++S+ AK+L+ ML + Sbjct: 266 AGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELINMMLLVNV 325 Query: 350 KERLTAAEILNHPWIREDGEAPDKPLDITVISRMKQ 457 +R +A ++L HPW+ +DG P+ ++V ++K+ Sbjct: 326 DQRFSAVQVLEHPWVNDDG-LPENEHQLSVAGKIKK 360
>MAPK2_CRILO (P49136) MAP kinase-activated protein kinase 2 (EC 2.7.11.1)| (MAPK-activated protein kinase 2) (MAPKAP kinase 2) (MAPKAPK-2) (P45-54 HSP27 kinase) (Fragment) Length = 329 Score = 108 bits (269), Expect = 2e-23 Identities = 54/147 (36%), Positives = 81/147 (55%), Gaps = 5/147 (3%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVL-KRRYGAEADIWSA 178 EN L+ +KR ++ LK TDFG + + YYVAPEVL +Y D+WS Sbjct: 119 ENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSL 178 Query: 179 GVILYILLSGVPPFWAEN----EEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQD 346 GVI+YILL G PPF++ + G+ + G +F + W +S K L++ +L+ + Sbjct: 179 GVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTE 238 Query: 347 PKERLTAAEILNHPWIREDGEAPDKPL 427 P +R+T E +NHPWI + + P PL Sbjct: 239 PTQRMTITEFMNHPWIMQSTKVPQTPL 265
>MAPK2_HUMAN (P49137) MAP kinase-activated protein kinase 2 (EC 2.7.11.1)| (MAPK-activated protein kinase 2) (MAPKAP kinase 2) (MAPKAPK-2) (MK2) Length = 400 Score = 108 bits (269), Expect = 2e-23 Identities = 54/147 (36%), Positives = 81/147 (55%), Gaps = 5/147 (3%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVL-KRRYGAEADIWSA 178 EN L+ +KR ++ LK TDFG + + YYVAPEVL +Y D+WS Sbjct: 190 ENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSL 249 Query: 179 GVILYILLSGVPPFWAEN----EEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQD 346 GVI+YILL G PPF++ + G+ + G +F + W +S K L++ +L+ + Sbjct: 250 GVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTE 309 Query: 347 PKERLTAAEILNHPWIREDGEAPDKPL 427 P +R+T E +NHPWI + + P PL Sbjct: 310 PTQRMTITEFMNHPWIMQSTKVPQTPL 336
>MAPK2_MOUSE (P49138) MAP kinase-activated protein kinase 2 (EC 2.7.11.1)| (MAPK-activated protein kinase 2) (MAPKAP kinase 2) (MAPKAPK-2) (MK2) Length = 386 Score = 108 bits (269), Expect = 2e-23 Identities = 54/147 (36%), Positives = 81/147 (55%), Gaps = 5/147 (3%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVL-KRRYGAEADIWSA 178 EN L+ +KR ++ LK TDFG + + YYVAPEVL +Y D+WS Sbjct: 176 ENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSL 235 Query: 179 GVILYILLSGVPPFWAEN----EEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQD 346 GVI+YILL G PPF++ + G+ + G +F + W +S K L++ +L+ + Sbjct: 236 GVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTE 295 Query: 347 PKERLTAAEILNHPWIREDGEAPDKPL 427 P +R+T E +NHPWI + + P PL Sbjct: 296 PTQRMTITEFMNHPWIMQSTKVPQTPL 322
>DCAK2_MOUSE (Q6PGN3) Serine/threonine-protein kinase DCAMKL2 (EC 2.7.11.1)| (Doublecortin-like and CAM kinase-like 2) Length = 756 Score = 107 bits (268), Expect = 2e-23 Identities = 56/142 (39%), Positives = 89/142 (62%), Gaps = 3/142 (2%) Frame = +2 Query: 41 LKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRR-YGAEADIWSAGVILYILLSGVPP 217 LK DFGL+ + + G+ YVAPE++ YG + D+W+AGVI YILL G PP Sbjct: 532 LKLGDFGLATVVEG--PLYTVCGTPTYVAPEIIAETGYGLKVDVWAAGVITYILLCGFPP 589 Query: 218 FWAEN--EEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHPW 391 F +EN +E +FD +L G ++F + W +I++ AK+L+ +ML+ + + R TA EIL+HPW Sbjct: 590 FRSENNLQEDLFDQILAGKLEFPAPYWDNITDSAKELISQMLQVNVEARCTAGEILSHPW 649 Query: 392 IREDGEAPDKPLDITVISRMKQ 457 + +D + + + V ++KQ Sbjct: 650 VSDDA-SQENNMQAEVTGKLKQ 670
>DAPK3_RAT (O88764) Death-associated protein kinase 3 (EC 2.7.11.1) (DAP| kinase 3) (DAP-like kinase) (Dlk) (ZIP-kinase) Length = 448 Score = 107 bits (268), Expect = 2e-23 Identities = 58/141 (41%), Positives = 85/141 (60%), Gaps = 6/141 (4%) Frame = +2 Query: 2 ENFLFLNKREDSP-LKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRR-YGAEADIWS 175 EN + L+K SP +K DFG++ + G +F+++ G+ +VAPE++ G EAD+WS Sbjct: 143 ENIMLLDKHAASPRIKLIDFGIAHRIEAGSEFKNIFGTPEFVAPEIVNYEPLGLEADMWS 202 Query: 176 AGVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKE 355 GVI YILLSG PF E ++ + + DF + + S S AKD ++R+L +DPK Sbjct: 203 IGVITYILLSGASPFLGETKQETLTNISAVNYDFDEEYFSSTSELAKDFIRRLLVKDPKR 262 Query: 356 RLTAAEILNHPWI----REDG 406 R+T A+ L H WI REDG Sbjct: 263 RMTIAQSLEHSWIKVRRREDG 283
>DAPK3_MOUSE (O54784) Death-associated protein kinase 3 (EC 2.7.11.1) (DAP| kinase 3) (DAP-like kinase) (Dlk) (ZIP-kinase) Length = 448 Score = 107 bits (268), Expect = 2e-23 Identities = 58/141 (41%), Positives = 85/141 (60%), Gaps = 6/141 (4%) Frame = +2 Query: 2 ENFLFLNKREDSP-LKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRR-YGAEADIWS 175 EN + L+K SP +K DFG++ + G +F+++ G+ +VAPE++ G EAD+WS Sbjct: 143 ENIMLLDKHAASPRIKLIDFGIAHRIEAGSEFKNIFGTPEFVAPEIVNYEPLGLEADMWS 202 Query: 176 AGVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKE 355 GVI YILLSG PF E ++ + + DF + + S S AKD ++R+L +DPK Sbjct: 203 IGVITYILLSGASPFLGETKQETLTNISAVNYDFDEEYFSSTSELAKDFIRRLLVKDPKR 262 Query: 356 RLTAAEILNHPWI----REDG 406 R+T A+ L H WI REDG Sbjct: 263 RMTIAQSLEHSWIKVRRREDG 283
>KCC1_EMENI (Q00771) Calcium/calmodulin-dependent protein kinase (EC 2.7.11.17)| (CMPK) Length = 414 Score = 107 bits (267), Expect = 3e-23 Identities = 64/183 (34%), Positives = 96/183 (52%), Gaps = 8/183 (4%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFF-KPGEQFRDLVGSAYYVAPEV-LKRRYGAEADIWS 175 EN L+L + DS L DFG++ P E + GS Y APEV LK+ +G DIWS Sbjct: 146 ENLLYLTRDLDSQLVLADFGIAKMLDNPAEVLTSMAGSFGYAAPEVMLKQGHGKAVDIWS 205 Query: 176 AGVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKE 355 GVI Y LL G PF +EN + + G + F W +S AKD + +L+ DP + Sbjct: 206 LGVITYTLLCGYSPFRSENLTDLIEECRSGRVVFHERYWKDVSKDAKDFILSLLQVDPAQ 265 Query: 356 RLTAAEILNHPWIREDGEAPDKPLDITVISRMKQFRAMNKLK------KVALKIVAESLS 517 R T+ E L HPW++ + + D ++ ++ + A ++LK K+A +I A + Sbjct: 266 RPTSEEALKHPWLKGESAS-----DRDLLPEIRAYIARSRLKRGIEIIKLANRIEALKMQ 320 Query: 518 EEE 526 EE+ Sbjct: 321 EED 323
>DCAK2_HUMAN (Q8N568) Serine/threonine-protein kinase DCAMKL2 (EC 2.7.11.1)| (Doublecortin-like and CAM kinase-like 2) Length = 766 Score = 107 bits (266), Expect = 3e-23 Identities = 56/142 (39%), Positives = 89/142 (62%), Gaps = 3/142 (2%) Frame = +2 Query: 41 LKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRR-YGAEADIWSAGVILYILLSGVPP 217 LK DFGL+ + + G+ YVAPE++ YG + DIW+AGVI YILL G PP Sbjct: 533 LKLGDFGLATVVEG--PLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCGFPP 590 Query: 218 FWAEN--EEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHPW 391 F +EN +E +FD +L G ++F + W +I++ AK+L+ +ML+ + + R TA +IL+HPW Sbjct: 591 FRSENNLQEDLFDQILAGKLEFPAPYWDNITDSAKELISQMLQVNVEARCTAGQILSHPW 650 Query: 392 IREDGEAPDKPLDITVISRMKQ 457 + +D + + + V ++KQ Sbjct: 651 VSDDA-SQENNMQAEVTGKLKQ 671
>KCC1_SCHPO (Q9P7I2) Calcium/calmodulin-dependent protein kinase type I (EC| 2.7.11.17) (CaMK-I) Length = 335 Score = 106 bits (265), Expect = 4e-23 Identities = 55/136 (40%), Positives = 80/136 (58%), Gaps = 3/136 (2%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLV--GSAYYVAPEVLKRR-YGAEADIW 172 EN L+ +K +S L DFGLS F++ + + + G+ Y+APEV +R YG D+W Sbjct: 158 ENLLYRSKDPNSDLLIADFGLSHFYEDSQYYMLMTACGTPEYMAPEVFRRTGYGKPVDMW 217 Query: 173 SAGVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPK 352 + GVI Y LLSG PF ++ + +A+L F+ W IS AKD +K+ L DP Sbjct: 218 AIGVITYFLLSGYTPFARPSQVEVIEAILANEYTFNDPCWSGISETAKDFIKKCLENDPS 277 Query: 353 ERLTAAEILNHPWIRE 400 +RLTAA+ L HP++ E Sbjct: 278 KRLTAADALKHPFLSE 293
>KPSH2_HUMAN (Q96QS6) Serine/threonine-protein kinase H2 (EC 2.7.11.1) (PSK-H2)| Length = 385 Score = 106 bits (264), Expect = 6e-23 Identities = 53/134 (39%), Positives = 85/134 (63%), Gaps = 3/134 (2%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQF--RDLVGSAYYVAPEVLKRR-YGAEADIW 172 EN L+ + E+S + TDFGL+ K + + L G+ Y+APEVL R+ Y + D+W Sbjct: 187 ENLLYYHPGEESKILITDFGLAYSGKKSGDWTMKTLCGTPEYIAPEVLLRKPYTSAVDMW 246 Query: 173 SAGVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPK 352 + GVI Y LLSG PF E++ ++ +LKG +++ +PWPSIS+ AKD + ++L + Sbjct: 247 ALGVITYALLSGFLPFDDESQTRLYRKILKGKYNYTGEPWPSISHLAKDFIDKLLILEAG 306 Query: 353 ERLTAAEILNHPWI 394 R++A + L+HPW+ Sbjct: 307 HRMSAGQALDHPWV 320
>CHK2_MOUSE (Q9Z265) Serine/threonine-protein kinase Chk2 (EC 2.7.11.1)| Length = 546 Score = 106 bits (264), Expect = 6e-23 Identities = 58/139 (41%), Positives = 76/139 (54%), Gaps = 5/139 (3%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRR----YGAEADI 169 EN L ++ ED +K TDFG S R L G+ Y+APEVL Y D Sbjct: 355 ENVLLSSQEEDCLIKITDFGQSKILGETSLMRTLCGTPTYLAPEVLVSNGTAGYSRAVDC 414 Query: 170 WSAGVILYILLSGVPPFWAENEE-GIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQD 346 WS GVIL+I LSG PPF + + D + G +F + W +S A DLVK++L D Sbjct: 415 WSLGVILFICLSGYPPFSEHKTQVSLKDQITSGKYNFIPEVWTDVSEEALDLVKKLLVVD 474 Query: 347 PKERLTAAEILNHPWIRED 403 PK RLT E LNHPW++++ Sbjct: 475 PKARLTTEEALNHPWLQDE 493
>DAPK1_MOUSE (Q80YE7) Death-associated protein kinase 1 (EC 2.7.11.1) (DAP| kinase 1) Length = 1442 Score = 104 bits (260), Expect = 2e-22 Identities = 58/165 (35%), Positives = 94/165 (56%), Gaps = 4/165 (2%) Frame = +2 Query: 2 ENFLFLNKREDSP-LKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRR-YGAEADIWS 175 EN + L++ P +K DFGL+ G +F+++ G+ +VAPE++ G EAD+WS Sbjct: 143 ENIMLLDRNVPKPRIKIIDFGLAHKIDFGNEFKNIFGTPEFVAPEIVNYEPLGLEADMWS 202 Query: 176 AGVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKE 355 GVI YILLSG PF + ++ V + DF + + + S AKD ++R+L +DPK+ Sbjct: 203 IGVITYILLSGASPFLGDTKQETLANVSAVNYDFEEEFFRNTSTLAKDFIRRLLVKDPKK 262 Query: 356 RLTAAEILNHPWI--REDGEAPDKPLDITVISRMKQFRAMNKLKK 484 R+T + L HPWI ++ +A + + + K+F A K K+ Sbjct: 263 RMTIQDSLQHPWIKPKDTQQALSRKASAVNMEKFKKFAARKKWKQ 307
>KPSH1_PINFU (Q4KTY1) Serine/threonine-protein kinase H1 homolog (EC 2.7.11.1)| Length = 415 Score = 104 bits (259), Expect = 2e-22 Identities = 53/133 (39%), Positives = 79/133 (59%), Gaps = 2/133 (1%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQF-RDLVGSAYYVAPEVLKRR-YGAEADIWS 175 EN L+ + DS + TDFGLS K E F R G+ Y+APE++ R+ Y + D+W+ Sbjct: 202 ENLLYYHPGHDSKIMITDFGLSSTRKGPENFMRTTCGTPEYIAPEIIARKPYMCQVDMWA 261 Query: 176 AGVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKE 355 GVI YILLSG PF EN+ ++ +LK ++ + W +S AKD + ++L P + Sbjct: 262 VGVITYILLSGTMPFDDENKTRLYRLILKAKYSYAGEHWKDVSAQAKDFIDKLLVVSPGD 321 Query: 356 RLTAAEILNHPWI 394 RL+AA+ L H W+ Sbjct: 322 RLSAADALKHQWL 334
>STK33_HUMAN (Q9BYT3) Serine/threonine-protein kinase 33 (EC 2.7.11.1)| Length = 514 Score = 104 bits (259), Expect = 2e-22 Identities = 53/144 (36%), Positives = 91/144 (63%), Gaps = 3/144 (2%) Frame = +2 Query: 41 LKATDFGLSVFFKPGEQ--FRDLVGSAYYVAPEVLKRR-YGAEADIWSAGVILYILLSGV 211 +K TDFGL+V + + + G+ Y+APEV+ Y + DIWS GV++Y+LL G Sbjct: 261 IKVTDFGLAVKKQSRSEAMLQATCGTPIYMAPEVISAHDYSQQCDIWSIGVVMYMLLRGE 320 Query: 212 PPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHPW 391 PPF A +EE +F+ + KG + F + W SIS+ AK ++K++++ DP R+TA E+L++ W Sbjct: 321 PPFLASSEEKLFELIRKGELHFENAVWNSISDCAKSVLKQLMKVDPAHRITAKELLDNQW 380 Query: 392 IREDGEAPDKPLDITVISRMKQFR 463 + + + +P + V+ MK+++ Sbjct: 381 LTGNKLSSVRPTN--VLEMMKEWK 402
>DAPK3_HUMAN (O43293) Death-associated protein kinase 3 (EC 2.7.11.1) (DAP| kinase 3) (DAP-like kinase) (Dlk) (ZIP-kinase) Length = 454 Score = 103 bits (257), Expect = 4e-22 Identities = 52/134 (38%), Positives = 82/134 (61%), Gaps = 2/134 (1%) Frame = +2 Query: 2 ENFLFLNKREDSP-LKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRR-YGAEADIWS 175 EN + L+K +P +K DFG++ + G +F+++ G+ +VAPE++ G EAD+WS Sbjct: 143 ENIMLLDKNVPNPRIKLIDFGIAHKIEAGNEFKNIFGTPEFVAPEIVNYEPLGLEADMWS 202 Query: 176 AGVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKE 355 GVI YILLSG PF E ++ + + DF + + + S AKD ++R+L +DPK Sbjct: 203 IGVITYILLSGASPFLGETKQETLTNISAVNYDFDEEYFSNTSELAKDFIRRLLVKDPKR 262 Query: 356 RLTAAEILNHPWIR 397 R+T A+ L H WI+ Sbjct: 263 RMTIAQSLEHSWIK 276
>MKNK1_XENTR (Q66JF3) MAP kinase-interacting serine/threonine-protein kinase 1| (EC 2.7.11.1) (MAP kinase signal-integrating kinase 1) (Mnk1) Length = 417 Score = 103 bits (256), Expect = 5e-22 Identities = 64/176 (36%), Positives = 92/176 (52%), Gaps = 29/176 (16%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLV--------GSAYYVAPEVLK----- 142 EN L K + SP+K DF L K + GSA Y+APEV++ Sbjct: 162 ENILCEFKDKVSPVKICDFDLGSGVKLNSACTPITTPELTTPCGSAEYMAPEVVEVFTEE 221 Query: 143 -RRYGAEADIWSAGVILYILLSGVPPF---------WAENE------EGIFDAVLKGHID 274 Y D+WS GVILYI+LSG PPF W E +F+++ +G + Sbjct: 222 ATFYDKRCDLWSLGVILYIMLSGYPPFVGNCGADCGWDRGEMCRVCQNKLFESIQEGKYE 281 Query: 275 FSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHPWIREDGEAPDKPLDITVI 442 F W ISN AKDL+ ++L +D KERL+AA++L HPW++ G+AP++ L ++ Sbjct: 282 FPEKDWSHISNSAKDLISKLLVRDAKERLSAAQVLQHPWLQ--GDAPERGLPTPLV 335
>DAPK1_HUMAN (P53355) Death-associated protein kinase 1 (EC 2.7.11.1) (DAP| kinase 1) Length = 1432 Score = 103 bits (256), Expect = 5e-22 Identities = 57/165 (34%), Positives = 94/165 (56%), Gaps = 4/165 (2%) Frame = +2 Query: 2 ENFLFLNKREDSP-LKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRR-YGAEADIWS 175 EN + L++ P +K DFGL+ G +F+++ G+ +VAPE++ G EAD+WS Sbjct: 143 ENIMLLDRNVPKPRIKIIDFGLAHKIDFGNEFKNIFGTPEFVAPEIVNYEPLGLEADMWS 202 Query: 176 AGVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKE 355 GVI YILLSG PF + ++ V + +F + + + S AKD ++R+L +DPK+ Sbjct: 203 IGVITYILLSGASPFLGDTKQETLANVSAVNYEFEDEYFSNTSALAKDFIRRLLVKDPKK 262 Query: 356 RLTAAEILNHPWI--REDGEAPDKPLDITVISRMKQFRAMNKLKK 484 R+T + L HPWI ++ +A + + + K+F A K K+ Sbjct: 263 RMTIQDSLQHPWIKPKDTQQALSRKASAVNMEKFKKFAARKKWKQ 307
>MKNK2_XENTR (Q66I46) MAP kinase-interacting serine/threonine-protein kinase 2| (EC 2.7.11.1) (MAP kinase signal-integrating kinase 2) (Mnk2) Length = 466 Score = 103 bits (256), Expect = 5e-22 Identities = 68/205 (33%), Positives = 100/205 (48%), Gaps = 30/205 (14%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDL--------VGSAYYVAPEVLKRR--- 148 EN L + + SP+K DF L K + GSA Y+APEV++ Sbjct: 208 ENILCESPHQVSPVKICDFDLGSGIKLNSDCSPISTPELLTPCGSAEYMAPEVVEAFNEE 267 Query: 149 ---YGAEADIWSAGVILYILLSGVPPF---------WAENE------EGIFDAVLKGHID 274 Y D+WS GVILYI+LSG PPF W E +F ++ +G + Sbjct: 268 ASIYDKRCDLWSLGVILYIMLSGYPPFVGHCGSDCGWDRGEACPACQNMLFVSIQEGKYE 327 Query: 275 FSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHPWIREDGEAPDKPLDITVI-SRM 451 F W IS+GAKDL+ ++L +D K+RL+AA++L HPW++ G APD L +I R Sbjct: 328 FPEKDWAHISSGAKDLISKLLLRDAKKRLSAAQVLQHPWVQ--GNAPDNTLPTPIILQRN 385 Query: 452 KQFRAMNKLKKVALKIVAESLSEEE 526 + + A+ + + + EE Sbjct: 386 SSAKDLTSFAAEAIAMNRQLMEREE 410
>MKNK1_BOVIN (Q58D94) MAP kinase-interacting serine/threonine-protein kinase 1| (EC 2.7.11.1) (MAP kinase signal-integrating kinase 1) (Mnk1) Length = 420 Score = 102 bits (255), Expect = 6e-22 Identities = 62/171 (36%), Positives = 90/171 (52%), Gaps = 29/171 (16%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLV--------GSAYYVAPEVLK----- 142 EN L + + SP+K DF L K + GSA Y+APEV++ Sbjct: 162 ENILCESPEKVSPVKICDFDLGSGVKLNNSCTPITTPELTTPCGSAEYMAPEVVEVFTDE 221 Query: 143 -RRYGAEADIWSAGVILYILLSGVPPF---------WAENE------EGIFDAVLKGHID 274 Y D+WS GV+LYI+LSG PPF W E +F+++ KG + Sbjct: 222 ATFYDKRCDLWSLGVVLYIMLSGYPPFVGHCGADCGWDRGEVCTVCQNKLFESIQKGKYE 281 Query: 275 FSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHPWIREDGEAPDKPL 427 F W ISN AKDL+ ++L +D K+RL+AA++L HPW++ G+AP++ L Sbjct: 282 FPDKDWAHISNEAKDLISKLLVRDAKQRLSAAQVLQHPWVQ--GQAPERGL 330
>MAPK2_DROME (P49071) MAP kinase-activated protein kinase 2 (EC 2.7.11.1)| (MAPK-activated protein kinase 2) (MAPKAP kinase 2) (MAPKAPK-2) Length = 359 Score = 102 bits (255), Expect = 6e-22 Identities = 52/147 (35%), Positives = 80/147 (54%), Gaps = 5/147 (3%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVL-KRRYGAEADIWSA 178 EN L+ + ++ LK TDFG + + + YYVAPEVL +Y DIWS Sbjct: 146 ENLLYTTTQPNATLKLTDFGFAKETFTSYTLQTPCYTPYYVAPEVLGPEKYDKSCDIWSL 205 Query: 179 GVILYILLSGVPPFWAEN----EEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQD 346 GV++YI++ G PPF++ + G+ + + G DF W ++S AKDL+K ML D Sbjct: 206 GVVMYIIMCGFPPFYSNHGLAISPGMKNRIRTGQYDFPDPEWTNVSQAAKDLIKGMLNVD 265 Query: 347 PKERLTAAEILNHPWIREDGEAPDKPL 427 P +RL +++++ WI + P PL Sbjct: 266 PSKRLRIQDVISNKWIAQYNAVPQTPL 292
>CHK2_HUMAN (O96017) Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (Cds1)| Length = 543 Score = 101 bits (252), Expect = 1e-21 Identities = 56/139 (40%), Positives = 74/139 (53%), Gaps = 5/139 (3%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVL----KRRYGAEADI 169 EN L ++ ED +K TDFG S R L G+ Y+APEVL Y D Sbjct: 351 ENVLLSSQEEDCLIKITDFGHSKILGETSLMRTLCGTPTYLAPEVLVSVGTAGYNRAVDC 410 Query: 170 WSAGVILYILLSGVPPFWAENEE-GIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQD 346 WS GVIL+I LSG PPF + + D + G +F + W +S A DLVK++L D Sbjct: 411 WSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVD 470 Query: 347 PKERLTAAEILNHPWIRED 403 PK R T E L HPW++++ Sbjct: 471 PKARFTTEEALRHPWLQDE 489
>CAKI_DROME (Q24210) Calcium/calmodulin-dependent protein kinase (EC 2.7.11.17)| (CAKI) (Peripheral plasma membrane protein CaMGUK) Length = 898 Score = 101 bits (252), Expect = 1e-21 Identities = 61/154 (39%), Positives = 88/154 (57%), Gaps = 5/154 (3%) Frame = +2 Query: 35 SPLKATDFGLSVFFKPGE----QFRDLVGSAYYVAPEVLKRR-YGAEADIWSAGVILYIL 199 +P+K FG ++ PG + VG +Y+APEV+ RR YG D+W AGV+L++L Sbjct: 156 APVKLGGFGSAIQL-PGTRETIETHGRVGCPHYMAPEVVTRRLYGKGCDVWGAGVMLHVL 214 Query: 200 LSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEIL 379 LSG PF + +V +G + F + W SIS AKDLV +ML +P RL+ E+L Sbjct: 215 LSGRLPFLGSGVR-LQQSVARGRLSFEAPEWKSISANAKDLVMKMLAANPHHRLSITEVL 273 Query: 380 NHPWIREDGEAPDKPLDITVISRMKQFRAMNKLK 481 +HPWIR+ + L TV +K++ A KLK Sbjct: 274 DHPWIRDRDKLQRTHLADTV-EELKRYNARRKLK 306
>MYLK_DICDI (P25323) Myosin light chain kinase (EC 2.7.11.18) (MLCK)| Length = 295 Score = 101 bits (252), Expect = 1e-21 Identities = 52/135 (38%), Positives = 73/135 (54%), Gaps = 1/135 (0%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRR-YGAEADIWSA 178 EN L +K + DFGLS + G+ YVAPEVL Y E D+WS Sbjct: 134 ENLLLKSKENHLEVAIADFGLSKIIGQTLVMQTACGTPSYVAPEVLNATGYDKEVDMWSI 193 Query: 179 GVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKER 358 GVI YILL G PPF+ + IF+ +++ + +F + W IS AKD + ++L D +R Sbjct: 194 GVITYILLCGFPPFYGDTVPEIFEQIMEANYEFPEEYWGGISKEAKDFIGKLLVVDVSKR 253 Query: 359 LTAAEILNHPWIRED 403 L A LNHPW++ + Sbjct: 254 LNATNALNHPWLKSN 268
>MKNK1_MOUSE (O08605) MAP kinase-interacting serine/threonine-protein kinase 1| (EC 2.7.11.1) (MAP kinase signal-integrating kinase 1) (Mnk1) Length = 427 Score = 101 bits (251), Expect = 2e-21 Identities = 61/171 (35%), Positives = 90/171 (52%), Gaps = 29/171 (16%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLV--------GSAYYVAPEVLK----- 142 EN L + + SP+K DF L K + GSA Y+APEV++ Sbjct: 174 ENILCESPEKVSPVKICDFDLGSGVKLNNSCTPITTPELTTPCGSAEYMAPEVVEVFRDE 233 Query: 143 -RRYGAEADIWSAGVILYILLSGVPPF---------WAENE------EGIFDAVLKGHID 274 Y D+WS GV+LYI+LSG PPF W E +F+++ +G + Sbjct: 234 ATFYDKRCDLWSLGVVLYIMLSGYPPFVGHCGADCGWDRGEVCRMCQNKLFESIQEGKYE 293 Query: 275 FSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHPWIREDGEAPDKPL 427 F W ISN AKDL+ ++L +D K+RL+AA++L HPW++ G+AP++ L Sbjct: 294 FPDKDWAHISNEAKDLISKLLVRDAKQRLSAAQVLQHPWVQ--GQAPERGL 342
>MYLK_CHICK (P11799) Myosin light chain kinase, smooth muscle and non-muscle| isozymes (EC 2.7.11.18) (MLCK) [Contains: Telokin] Length = 1906 Score = 101 bits (251), Expect = 2e-21 Identities = 63/184 (34%), Positives = 98/184 (53%), Gaps = 5/184 (2%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRR-YGAEADIWSA 178 EN + +NK S +K DFGL+ + + L G+ +VAPEV+ G E D+WS Sbjct: 1578 ENIMCVNKTGTS-IKLIDFGLARRLESAGSLKVLFGTPEFVAPEVINYEPIGYETDMWSI 1636 Query: 179 GVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKER 358 GVI YIL+SG+ PF +N+ V DF + + IS+ AKD + +L++D K R Sbjct: 1637 GVICYILVSGLSPFMGDNDNETLANVTSATWDFDDEAFDEISDDAKDFISNLLKKDMKSR 1696 Query: 359 LTAAEILNHPWIREDGEAPDKPLDITVIS--RMKQFRAMNKLKKV--ALKIVAESLSEEE 526 L + L HPW+++D K ++ +S RMK++ A K +K A++ + S Sbjct: 1697 LNCTQCLQHPWLQKD----TKNMEAKKLSKDRMKKYMARRKWQKTGHAVRAIGRLSSMAM 1752 Query: 527 IVGL 538 I G+ Sbjct: 1753 ISGM 1756
>MKNK1_HUMAN (Q9BUB5) MAP kinase-interacting serine/threonine-protein kinase 1| (EC 2.7.11.1) (MAP kinase signal-integrating kinase 1) (Mnk1) Length = 465 Score = 100 bits (250), Expect = 2e-21 Identities = 61/171 (35%), Positives = 90/171 (52%), Gaps = 29/171 (16%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLV--------GSAYYVAPEVLK----- 142 EN L + + SP+K DF L K + GSA Y+APEV++ Sbjct: 215 ENILCESPEKVSPVKICDFDLGSGMKLNNSCTPITTPELTTPCGSAEYMAPEVVEVFTDQ 274 Query: 143 -RRYGAEADIWSAGVILYILLSGVPPF---------WAENE------EGIFDAVLKGHID 274 Y D+WS GV+LYI+LSG PPF W E +F+++ +G + Sbjct: 275 ATFYDKRCDLWSLGVVLYIMLSGYPPFVGHCGADCGWDRGEVCRVCQNKLFESIQEGKYE 334 Query: 275 FSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHPWIREDGEAPDKPL 427 F W IS+ AKDL+ ++L +D K+RL+AA++L HPW++ G+AP+K L Sbjct: 335 FPDKDWAHISSEAKDLISKLLVRDAKQRLSAAQVLQHPWVQ--GQAPEKGL 383
>ST17A_RABIT (Q9GM70) Serine/threonine-protein kinase 17A (EC 2.7.11.1) (DAP| kinase-related apoptosis-inducing protein kinase 1) (rDRAK1) Length = 397 Score = 99.8 bits (247), Expect = 5e-21 Identities = 45/134 (33%), Positives = 81/134 (60%), Gaps = 1/134 (0%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRR-YGAEADIWSA 178 +N L ++ +K DFGLS K E+ R+++G+ YVAPE+L D+WS Sbjct: 173 QNILLTSESPLGDIKIVDFGLSRIVKNSEELREIMGTPEYVAPEILSYDPISMATDMWSI 232 Query: 179 GVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKER 358 GV+ Y++L+G+ PF +N++ F + + ++ +S + + ++S A D +K++L + P++R Sbjct: 233 GVLTYVMLTGISPFLGDNKQETFLNISQMNLSYSEEEFDTVSESAVDFIKKLLVKKPEDR 292 Query: 359 LTAAEILNHPWIRE 400 TA E L HPW+ + Sbjct: 293 ATAEECLKHPWLTQ 306
>MKNK2_HUMAN (Q9HBH9) MAP kinase-interacting serine/threonine-protein kinase 2| (EC 2.7.11.1) (MAP kinase signal-integrating kinase 2) (Mnk2) Length = 465 Score = 99.4 bits (246), Expect = 7e-21 Identities = 71/216 (32%), Positives = 104/216 (48%), Gaps = 38/216 (17%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDL--------VGSAYYVAPEVLKRR--- 148 EN L + + SP+K DF L K + GSA Y+APEV++ Sbjct: 209 ENILCEHPNQVSPVKICDFDLGSGIKLNGDCSPISTPELLTPCGSAEYMAPEVVEAFSEE 268 Query: 149 ---YGAEADIWSAGVILYILLSGVPPF---------WAENE------EGIFDAVLKGHID 274 Y D+WS GVILYILLSG PPF W E +F+++ +G + Sbjct: 269 ASIYDKRCDLWSLGVILYILLSGYPPFVGRCGSDCGWDRGEACPACQNMLFESIQEGKYE 328 Query: 275 FSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHPWIREDGEAPDKPLDITVISRMK 454 F W IS AKDL+ ++L +D K+RL+AA++L HPW++ G AP+ L ++ ++ Sbjct: 329 FPDKDWAHISCAAKDLISKLLVRDAKQRLSAAQVLQHPWVQ--GCAPENTLPTPMV--LQ 384 Query: 455 QFRAMNKLKKVALKIVA---------ESLSEEEIVG 535 + L A + +A E L+EEE G Sbjct: 385 RNSCAKDLTSFAAEAIAMNRQLAQHDEDLAEEEAAG 420
>MKNK1_RAT (Q4G050) MAP kinase-interacting serine/threonine-protein kinase 1| (EC 2.7.11.1) (MAP kinase signal-integrating kinase 1) (Mnk1) Length = 413 Score = 99.0 bits (245), Expect = 9e-21 Identities = 60/171 (35%), Positives = 89/171 (52%), Gaps = 29/171 (16%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLV--------GSAYYVAPEVLK----- 142 EN L + + SP+K DF L K + GSA Y+APEV++ Sbjct: 162 ENILCESPEKVSPVKICDFDLGSGVKLNNSCTPITTPELTTPCGSAEYMAPEVVEVFRDE 221 Query: 143 -RRYGAEADIWSAGVILYILLSGVPPF---------WAENE------EGIFDAVLKGHID 274 Y D+WS GV+LYI+LSG PPF W E +F+++ +G + Sbjct: 222 ATFYDKRCDLWSLGVVLYIMLSGYPPFVGHCGADCGWDRGEVCRMCQNKLFESIQEGKYE 281 Query: 275 FSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHPWIREDGEAPDKPL 427 F W IS AKDL+ ++L +D K+RL+AA++L HPW++ G+AP++ L Sbjct: 282 FPDKDWAHISTEAKDLISKLLVRDAKQRLSAAQVLQHPWVQ--GQAPERGL 330
>MKNK2_XENLA (Q6P431) MAP kinase-interacting serine/threonine-protein kinase 2| (EC 2.7.11.1) (MAP kinase signal-integrating kinase 2) (Mnk2) Length = 467 Score = 98.6 bits (244), Expect = 1e-20 Identities = 67/205 (32%), Positives = 98/205 (47%), Gaps = 30/205 (14%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDL--------VGSAYYVAPEVLKRR--- 148 EN L + + SP+K DF L K + GSA Y+APEV++ Sbjct: 208 ENILCESPHQVSPVKICDFDLGSGIKLNSDCSPISTPELLTPCGSAEYMAPEVVEAFNEE 267 Query: 149 ---YGAEADIWSAGVILYILLSGVPPF---------WAENE------EGIFDAVLKGHID 274 Y D+WS GVILYI+LSG PPF W E +F ++ +G + Sbjct: 268 ASIYDKRCDLWSLGVILYIMLSGYPPFVGHCGSDCGWDRGEACPACQNMLFVSIQEGKYE 327 Query: 275 FSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHPWIREDGEAPDKPLDITVI-SRM 451 F W IS GAKDL+ ++L +D K+RL+AA++L HPW++ G AP L +I R Sbjct: 328 FPEKDWAHISYGAKDLISKLLLRDAKKRLSAAQVLQHPWVQ--GNAPYNTLPTPIILQRN 385 Query: 452 KQFRAMNKLKKVALKIVAESLSEEE 526 + + A+ + + + EE Sbjct: 386 SSAKDLTSFAAEAIAMNRQLMEREE 410
>KCC1_YEAST (P27466) Calcium/calmodulin-dependent protein kinase I (EC| 2.7.11.17) Length = 446 Score = 98.2 bits (243), Expect = 2e-20 Identities = 57/135 (42%), Positives = 74/135 (54%), Gaps = 4/135 (2%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFR-DLVGSAYYVAPEVLKRR-YGAEADIWS 175 EN L+++K ++SPL DFG++ K E+ GS YVAPEVL + +G DIWS Sbjct: 165 ENLLYIDKSDESPLVVADFGIAKRLKSDEELLYKPAGSLGYVAPEVLTQDGHGKPCDIWS 224 Query: 176 AGVILYILLSGVPPFWAENEEGIFDAVLKGH--IDFSSDPWPSISNGAKDLVKRMLRQDP 349 GVI Y LL G F AE + D G + F W S+SN AK + + L DP Sbjct: 225 IGVITYTLLCGYSAFRAERVQDFLDECTTGEYPVKFHRPYWDSVSNKAKQFILKALNLDP 284 Query: 350 KERLTAAEILNHPWI 394 +R TAAE+L PWI Sbjct: 285 SKRPTAAELLEDPWI 299
>MKNK1_XENLA (Q9YGW0) MAP kinase-interacting serine/threonine-protein kinase 1| (EC 2.7.11.1) (MAP kinase signal-integrating kinase 1) (Mnk1) Length = 418 Score = 97.4 bits (241), Expect = 3e-20 Identities = 62/176 (35%), Positives = 90/176 (51%), Gaps = 29/176 (16%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLV--------GSAYYVAPEVLK----- 142 EN L K + SP+K DF L K + GSA Y+APEV++ Sbjct: 162 ENILCEFKDKVSPVKICDFDLGSGVKLNSACTTITTPELTTPCGSAEYMAPEVVEVFTEE 221 Query: 143 -RRYGAEADIWSAGVILYILLSGVPPF---------WAENE------EGIFDAVLKGHID 274 Y D+WS GVILYI+LSG PPF W E +F+++ +G + Sbjct: 222 ATFYDKRCDLWSLGVILYIMLSGYPPFVGNCGTDCGWDRGEVCRVCQNKLFESIQEGKYE 281 Query: 275 FSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHPWIREDGEAPDKPLDITVI 442 F W IS AKDL+ ++L +D KERL+A ++L HPW++ G+AP++ L ++ Sbjct: 282 FPEKDWSHISISAKDLISKLLVRDAKERLSAFQVLQHPWLQ--GDAPERGLPTPLV 335
>MYLK_BOVIN (Q28824) Myosin light chain kinase, smooth muscle (EC 2.7.11.18)| (MLCK) [Contains: Telokin] Length = 1176 Score = 97.4 bits (241), Expect = 3e-20 Identities = 62/184 (33%), Positives = 96/184 (52%), Gaps = 5/184 (2%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRR-YGAEADIWSA 178 EN + +NK + +K DFGL+ + + L G+ +VAPEV+ G D+WS Sbjct: 850 ENIMCVNKT-GTRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINYEPIGYATDMWSI 908 Query: 179 GVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKER 358 GVI YIL+SG+ PF +N+ V DF + + IS+ AKD + +L++D K R Sbjct: 909 GVICYILVSGLSPFMGDNDNETLANVTSATWDFDDEAFDEISDDAKDFISNLLKKDMKNR 968 Query: 359 LTAAEILNHPWIREDGEAPDKPLDITVIS--RMKQFRAMNKLKKV--ALKIVAESLSEEE 526 L + L HPW+ +D K ++ +S RMK++ A K +K A++ + S Sbjct: 969 LNCTQCLQHPWLMKD----TKNMEAKKLSKDRMKKYMARRKWQKTGNAVRAIGRLSSMAM 1024 Query: 527 IVGL 538 I GL Sbjct: 1025 ISGL 1028
>KIN1_SCHPO (P22987) Protein kinase kin1 (EC 2.7.11.1)| Length = 891 Score = 97.4 bits (241), Expect = 3e-20 Identities = 64/192 (33%), Positives = 98/192 (51%), Gaps = 19/192 (9%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRR--YGAEADIWS 175 EN L ++K D +K DFGLS ++ + R GS Y+ APE+L + G E D+WS Sbjct: 270 ENIL-ISKTGD--IKIIDFGLSNLYRRQSRLRTFCGSLYFAAPELLNAQPYIGPEVDVWS 326 Query: 176 AGVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKE 355 G++LY+L+ G PF +N + + KG +++ S +S+ K L+ RML DP + Sbjct: 327 FGIVLYVLVCGKVPFDDQNMSALHAKIKKGTVEYPS----YLSSDCKGLLSRMLVTDPLK 382 Query: 356 RLTAAEILNHPWIREDGEAPDK-----------PLDITVISRMKQF------RAMNKLKK 484 R T E+LNHPW+ + E P PLD +I M F + + +L K Sbjct: 383 RATLEEVLNHPWMIRNYEGPPASFAPERSPITLPLDPEIIREMNGFDFGPPEKIVRELTK 442 Query: 485 VALKIVAESLSE 520 V +SL++ Sbjct: 443 VISSEAYQSLAK 454
>MYLK_HUMAN (Q15746) Myosin light chain kinase, smooth muscle and non-muscle| isozymes (EC 2.7.11.18) (MLCK) [Contains: Telokin (Kinase-related protein) (KRP)] Length = 1914 Score = 97.1 bits (240), Expect = 4e-20 Identities = 62/184 (33%), Positives = 96/184 (52%), Gaps = 5/184 (2%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRR-YGAEADIWSA 178 EN + +NK + +K DFGL+ + + L G+ +VAPEV+ G D+WS Sbjct: 1589 ENIMCVNKT-GTRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINYEPIGYATDMWSI 1647 Query: 179 GVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKER 358 GVI YIL+SG+ PF +N+ V DF + + IS+ AKD + +L++D K R Sbjct: 1648 GVICYILVSGLSPFMGDNDNETLANVTSATWDFDDEAFDEISDDAKDFISNLLKKDMKNR 1707 Query: 359 LTAAEILNHPWIREDGEAPDKPLDITVIS--RMKQFRAMNKLKKV--ALKIVAESLSEEE 526 L + L HPW+ +D K ++ +S RMK++ A K +K A++ + S Sbjct: 1708 LDCTQCLQHPWLMKD----TKNMEAKKLSKDRMKKYMARRKWQKTGNAVRAIGRLSSMAM 1763 Query: 527 IVGL 538 I GL Sbjct: 1764 ISGL 1767
>LIN2_CAEEL (P54936) Protein lin-2 (Abnormal cell lineage protein 2)| Length = 961 Score = 97.1 bits (240), Expect = 4e-20 Identities = 57/176 (32%), Positives = 95/176 (53%), Gaps = 3/176 (1%) Frame = +2 Query: 5 NFLFLNKREDSPLKATDFGLSVFFKP--GEQFRDLVGSAYYVAPEVLKR-RYGAEADIWS 175 N + +K +PLK FG++ G VG ++APE++++ R +DIWS Sbjct: 151 NLVLASKDTSAPLKLCGFGVAKDLSEIGGSMACGRVGVPQFMAPEIVRKDRVSCSSDIWS 210 Query: 176 AGVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKE 355 +GV+L++LL+G PF + I++ +++ +D P+IS A++LV+RML DP + Sbjct: 211 SGVVLFLLLAGRLPFSGSTSD-IYERIMQTDVDVDGY-MPNISESARNLVRRMLNADPSK 268 Query: 356 RLTAAEILNHPWIREDGEAPDKPLDITVISRMKQFRAMNKLKKVALKIVAESLSEE 523 R++A E LNH WIR+ + VI +M+++ KLK L V +E Sbjct: 269 RISAKEALNHEWIRDKEHMASRKHMNDVIDQMRRYNESRKLKSNVLSAVNSGRFDE 324
>SNRK_RAT (Q63553) SNF-related serine/threonine-protein kinase (EC 2.7.11.1)| (SNF1-related kinase) Length = 746 Score = 97.1 bits (240), Expect = 4e-20 Identities = 58/150 (38%), Positives = 84/150 (56%), Gaps = 2/150 (1%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKR-RYGAEA-DIWS 175 EN +F K+ +K TDFG S F+PG++ GS Y APE+L Y A A DIWS Sbjct: 143 ENVVFFEKQ--GLVKLTDFGFSNKFQPGKKLTTSCGSLAYSAPEILLGDEYDAPAVDIWS 200 Query: 176 AGVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKE 355 GVIL++L+ G PPF N+ ++ D P +S G +DL+ RML++DPK Sbjct: 201 LGVILFMLVCGQPPFQEANDSETLTMIM----DCKYTVPPRVSAGCRDLITRMLQRDPKR 256 Query: 356 RLTAAEILNHPWIREDGEAPDKPLDITVIS 445 R + EI +HPW++ +P +I ++S Sbjct: 257 RASLEEIESHPWLQGVDPSPATKYNIPLVS 286
>MYLK_MOUSE (Q6PDN3) Myosin light chain kinase, smooth muscle and non-muscle| isozymes (EC 2.7.11.18) (MLCK) [Contains: Telokin (Kinase-related protein) (KRP)] Length = 1941 Score = 97.1 bits (240), Expect = 4e-20 Identities = 62/184 (33%), Positives = 96/184 (52%), Gaps = 5/184 (2%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRR-YGAEADIWSA 178 EN + +NK + +K DFGL+ + + L G+ +VAPEV+ G D+WS Sbjct: 1611 ENIMCVNKT-GTRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINYEPIGYATDMWSI 1669 Query: 179 GVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKER 358 GVI YIL+SG+ PF +N+ V DF + + IS+ AKD + +L++D K R Sbjct: 1670 GVICYILVSGLSPFMGDNDNETLANVTSATWDFDDEAFDEISDDAKDFISNLLKKDMKNR 1729 Query: 359 LTAAEILNHPWIREDGEAPDKPLDITVIS--RMKQFRAMNKLKKV--ALKIVAESLSEEE 526 L + L HPW+ +D K ++ +S RMK++ A K +K A++ + S Sbjct: 1730 LDCTQCLQHPWLMKD----TKNMEAKKLSKDRMKKYMARRKWQKTGNAVRAIGRLSSMAM 1785 Query: 527 IVGL 538 I GL Sbjct: 1786 ISGL 1789
>SNRK_MOUSE (Q8VDU5) SNF-related serine/threonine-protein kinase (EC 2.7.11.1)| (SNF1-related kinase) Length = 748 Score = 97.1 bits (240), Expect = 4e-20 Identities = 58/150 (38%), Positives = 84/150 (56%), Gaps = 2/150 (1%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKR-RYGAEA-DIWS 175 EN +F K+ +K TDFG S F+PG++ GS Y APE+L Y A A DIWS Sbjct: 143 ENVVFFEKQ--GLVKLTDFGFSNKFQPGKKLTTSCGSLAYSAPEILLGDEYDAPAVDIWS 200 Query: 176 AGVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKE 355 GVIL++L+ G PPF N+ ++ D P +S G +DL+ RML++DPK Sbjct: 201 LGVILFMLVCGQPPFQEANDSETLTMIM----DCKYTVPPRVSAGCRDLITRMLQRDPKR 256 Query: 356 RLTAAEILNHPWIREDGEAPDKPLDITVIS 445 R + EI +HPW++ +P +I ++S Sbjct: 257 RASLEEIESHPWLQGVDPSPATKYNIPLVS 286
>MKNK2_RAT (Q5U2N4) MAP kinase-interacting serine/threonine-protein kinase 2| (EC 2.7.11.1) (MAP kinase signal-integrating kinase 2) (Mnk2) Length = 459 Score = 96.7 bits (239), Expect = 5e-20 Identities = 62/176 (35%), Positives = 89/176 (50%), Gaps = 29/176 (16%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDL--------VGSAYYVAPEVLKRR--- 148 EN L + + SP+K DF L K + GSA Y+APEV++ Sbjct: 209 ENILCEHPNQVSPVKICDFDLGSGIKLNGDCSPISTPELLTPCGSAEYMAPEVVEAFSEE 268 Query: 149 ---YGAEADIWSAGVILYILLSGVPPF---------WAENE------EGIFDAVLKGHID 274 Y D+WS GVILYILLSG PPF W E +F+++ +G + Sbjct: 269 ASIYDKRCDLWSLGVILYILLSGYPPFVGHCGSDCGWDRGEACPACQNMLFESIQEGKYE 328 Query: 275 FSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHPWIREDGEAPDKPLDITVI 442 F W IS AKDL+ ++L +D K+RL+AA++L HPW++ G AP+ L ++ Sbjct: 329 FPDKDWSHISFAAKDLISKLLVRDAKQRLSAAQVLQHPWVQ--GCAPENTLPTPLV 382
>MKNK2_MOUSE (Q8CDB0) MAP kinase-interacting serine/threonine-protein kinase 2| (EC 2.7.11.1) (MAP kinase signal-integrating kinase 2) (Mnk2) Length = 459 Score = 96.7 bits (239), Expect = 5e-20 Identities = 62/176 (35%), Positives = 89/176 (50%), Gaps = 29/176 (16%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDL--------VGSAYYVAPEVLKRR--- 148 EN L + + SP+K DF L K + GSA Y+APEV++ Sbjct: 209 ENILCEHPNQVSPVKICDFDLGSGIKLNGDCSPISTPELLTPCGSAEYMAPEVVEAFSEE 268 Query: 149 ---YGAEADIWSAGVILYILLSGVPPF---------WAENE------EGIFDAVLKGHID 274 Y D+WS GVILYILLSG PPF W E +F+++ +G + Sbjct: 269 ASIYDKRCDLWSLGVILYILLSGYPPFVGHCGSDCGWDRGEACPACQNMLFESIQEGKYE 328 Query: 275 FSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHPWIREDGEAPDKPLDITVI 442 F W IS AKDL+ ++L +D K+RL+AA++L HPW++ G AP+ L ++ Sbjct: 329 FPDKDWSHISFAAKDLISKLLVRDAKQRLSAAQVLQHPWVQ--GCAPENTLPTPLV 382
>DAPK2_MOUSE (Q8VDF3) Death-associated protein kinase 2 (EC 2.7.11.1) (DAP| kinase 2) (DAP-kinase-related protein 1) (DRP-1) Length = 370 Score = 95.5 bits (236), Expect = 1e-19 Identities = 50/133 (37%), Positives = 78/133 (58%), Gaps = 2/133 (1%) Frame = +2 Query: 2 ENFLFLNKREDSP-LKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRR-YGAEADIWS 175 EN + L+K P +K DFGL+ + G +F+++ G+ +VAPE++ G EAD+WS Sbjct: 153 ENIMLLDKNIPIPHIKLIDFGLAHEIEDGVEFKNIFGTPEFVAPEIVNYEPLGLEADMWS 212 Query: 176 AGVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKE 355 GVI YILLSG PF + ++ + DF + + S AKD ++++L ++ ++ Sbjct: 213 IGVITYILLSGASPFLGDTKQETLANITAVSYDFDEEFFSQTSELAKDFIRKLLVKETRK 272 Query: 356 RLTAAEILNHPWI 394 RLT E L HPWI Sbjct: 273 RLTIQEALRHPWI 285
>DAPK2_HUMAN (Q9UIK4) Death-associated protein kinase 2 (EC 2.7.11.1) (DAP| kinase 2) (DAP-kinase-related protein 1) (DRP-1) Length = 370 Score = 95.5 bits (236), Expect = 1e-19 Identities = 50/133 (37%), Positives = 78/133 (58%), Gaps = 2/133 (1%) Frame = +2 Query: 2 ENFLFLNKREDSP-LKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRR-YGAEADIWS 175 EN + L+K P +K DFGL+ + G +F+++ G+ +VAPE++ G EAD+WS Sbjct: 153 ENIMLLDKNIPIPHIKLIDFGLAHEIEDGVEFKNIFGTPEFVAPEIVNYEPLGLEADMWS 212 Query: 176 AGVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKE 355 GVI YILLSG PF + ++ + DF + + S AKD ++++L ++ ++ Sbjct: 213 IGVITYILLSGASPFLGDTKQETLANITAVSYDFDEEFFSQTSELAKDFIRKLLVKETRK 272 Query: 356 RLTAAEILNHPWI 394 RLT E L HPWI Sbjct: 273 RLTIQEALRHPWI 285
>SNRK_HUMAN (Q9NRH2) SNF-related serine/threonine-protein kinase (EC 2.7.11.1)| (SNF1-related kinase) Length = 765 Score = 95.1 bits (235), Expect = 1e-19 Identities = 58/150 (38%), Positives = 82/150 (54%), Gaps = 2/150 (1%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKR-RYGAEA-DIWS 175 EN +F K+ +K TDFG S F+PG++ GS Y APE+L Y A A DIWS Sbjct: 143 ENVVFFEKQ--GLVKLTDFGFSNKFQPGKKLTTSCGSLAYSAPEILLGDEYDAPAVDIWS 200 Query: 176 AGVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKE 355 GVIL++L+ G PPF N+ ++ S +S KDL+ RML++DPK Sbjct: 201 LGVILFMLVCGQPPFQEANDSETLTMIMDCKYTVPSH----VSKECKDLITRMLQRDPKR 256 Query: 356 RLTAAEILNHPWIREDGEAPDKPLDITVIS 445 R + EI NHPW++ +P +I ++S Sbjct: 257 RASLEEIENHPWLQGVDPSPATKYNIPLVS 286
>MYLK_RABIT (P29294) Myosin light chain kinase, smooth muscle (EC 2.7.11.18)| (MLCK) [Contains: Telokin] Length = 1147 Score = 94.7 bits (234), Expect = 2e-19 Identities = 62/184 (33%), Positives = 97/184 (52%), Gaps = 5/184 (2%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRRYGAEA-DIWSA 178 EN + +NK + +K DFGL+ + + L G+ +VAPEV+ + A D+WS Sbjct: 821 ENIMCVNKT-GTRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINYEPISYATDMWSI 879 Query: 179 GVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKER 358 GVI YIL+SG+ PF +N+ V DF + + IS+ AKD + +L++D K R Sbjct: 880 GVICYILVSGLSPFMGDNDNETLANVTSATWDFDDEAFDEISDDAKDFISNLLKKDMKNR 939 Query: 359 LTAAEILNHPWIREDGEAPDKPLDITVIS--RMKQFRAMNKLKKV--ALKIVAESLSEEE 526 L + L HPW+ +D K ++ +S RMK++ A K +K A++ + S Sbjct: 940 LDCTQCLQHPWLMKD----TKNMEAKKLSKDRMKKYMARRKWQKTGNAVRAIGRLSSMAM 995 Query: 527 IVGL 538 I GL Sbjct: 996 ISGL 999
>KCC2_YEAST (P22517) Calcium/calmodulin-dependent protein kinase II (EC| 2.7.11.17) Length = 447 Score = 94.0 bits (232), Expect = 3e-19 Identities = 73/206 (35%), Positives = 105/206 (50%), Gaps = 7/206 (3%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLV----GSAYYVAPEVLKRR-YGAEAD 166 EN L+++K E+SPL DFG++ K GE+ DL+ GS YVAPEVL + +G D Sbjct: 175 ENVLYVDKSENSPLVIADFGIAKQLK-GEE--DLIYKAAGSLGYVAPEVLTQDGHGKPCD 231 Query: 167 IWSAGVILYILLSGVPPFWAENEEGIFDAVLKGH--IDFSSDPWPSISNGAKDLVKRMLR 340 IWS GVI Y LL G PF AE+ EG + + F W +IS K + + LR Sbjct: 232 IWSIGVITYTLLCGYSPFIAESVEGFMEECTASRYPVTFHMPYWDNISIDVKRFILKALR 291 Query: 341 QDPKERLTAAEILNHPWIREDGEAPDKPLDITVISRMKQFRAMNKLKKVALKIVAESLSE 520 +P +R TA E+L+ PWI + ++ +K+ ++ K + A++IV Sbjct: 292 LNPADRPTATELLDDPWI-----TSKRVETSNILPDVKKGFSLRKKLRDAIEIVK---LN 343 Query: 521 EEIVGLREMFKSLDTDNSGTITLDEL 598 I LR M+ SL D I + L Sbjct: 344 NRIKRLRNMY-SLGDDGDNDIEENSL 368
>ST17A_HUMAN (Q9UEE5) Serine/threonine-protein kinase 17A (EC 2.7.11.1) (DAP| kinase-related apoptosis-inducing protein kinase 1) Length = 414 Score = 93.6 bits (231), Expect = 4e-19 Identities = 43/134 (32%), Positives = 78/134 (58%), Gaps = 1/134 (0%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRR-YGAEADIWSA 178 +N L ++ +K DFGLS K E+ R+++G+ YVAPE+L D+WS Sbjct: 190 QNILLTSESPLGDIKIVDFGLSRILKNSEELREIMGTPEYVAPEILSYDPISMATDMWSI 249 Query: 179 GVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKER 358 GV+ Y++L+G+ PF +++ F + + ++ +S + + +S A D ++ +L + P++R Sbjct: 250 GVLTYVMLTGISPFLGNDKQETFLNISQMNLSYSEEEFDVLSESAVDFIRTLLVKKPEDR 309 Query: 359 LTAAEILNHPWIRE 400 TA E L HPW+ + Sbjct: 310 ATAEECLKHPWLTQ 323
>MYLK_SHEEP (O02827) Myosin light chain kinase, smooth muscle (EC 2.7.11.18)| (MLCK) [Contains: Telokin] (Fragment) Length = 438 Score = 93.6 bits (231), Expect = 4e-19 Identities = 61/184 (33%), Positives = 94/184 (51%), Gaps = 5/184 (2%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRR-YGAEADIWSA 178 EN + +NK + +K DFGL+ + + L G+ +VAPEV+ G D+WS Sbjct: 111 ENIMCVNKT-GTRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINYEPIGYATDMWSI 169 Query: 179 GVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKER 358 GVI YIL+SG+ PF +N+ V DF + + IS+ AKD + +L++D K R Sbjct: 170 GVICYILVSGLSPFMGDNDNETLANVTSATWDFDDEAFDEISDDAKDFISNLLKKDIKNR 229 Query: 359 LTAAEILNHPWIREDGEAPDKPLDITVIS--RMKQFRAMNKLKKV--ALKIVAESLSEEE 526 L + L HPW+ K ++ +S RMK++ A K +K A++ + S Sbjct: 230 LNCTQCLQHPWL----XXXTKNMEAKKLSKHRMKKYMARRKWQKTGNAVRAIGRLSSMAM 285 Query: 527 IVGL 538 I GL Sbjct: 286 ISGL 289
>KPK2_PLAFK (Q02595) Probable serine/threonine-protein kinase 2 (EC 2.7.11.1)| Length = 510 Score = 93.2 bits (230), Expect = 5e-19 Identities = 53/132 (40%), Positives = 74/132 (56%), Gaps = 2/132 (1%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFK-PGEQFRDLVGSAYYVAPEVLK-RRYGAEADIWS 175 EN + N + S LK DFGL+ F P R GS YVAPE+LK YG + DI+S Sbjct: 234 ENLMLENPNDPSSLKIIDFGLASFLNSPSMNMR--CGSPGYVAPEILKCASYGTKVDIFS 291 Query: 176 AGVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKE 355 GVIL+ +L G PPF N + IF ++ HI F++ W + S K+++ M ++P + Sbjct: 292 LGVILFNILCGYPPFRGNNVKEIFKKNMRCHISFNTKHWINKSESVKEIILWMCCKNPDD 351 Query: 356 RLTAAEILNHPW 391 R TA + L H W Sbjct: 352 RCTALQALGHQW 363
>KS6A1_RAT (Q63531) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1)| (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 735 Score = 92.4 bits (228), Expect = 9e-19 Identities = 48/110 (43%), Positives = 65/110 (59%), Gaps = 4/110 (3%) Frame = +2 Query: 110 SAYYVAPEVLKRR-YGAEADIWSAGVILYILLSGVPPFW---AENEEGIFDAVLKGHIDF 277 +A +VAPEVLKR+ Y DIWS GV+LY +L+G PF ++ E I + G Sbjct: 577 TANFVAPEVLKRQGYDEGCDIWSLGVLLYTMLAGYTPFANGPSDTPEEILTRISSGKFTL 636 Query: 278 SSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHPWIREDGEAPDKPL 427 S W ++S AKDLV +ML DP +RLTA ++L HPWI + + P L Sbjct: 637 SGGNWNTVSETAKDLVSKMLHVDPHQRLTAKQVLQHPWITQKDKLPQSQL 686 Score = 52.8 bits (125), Expect = 8e-07 Identities = 34/113 (30%), Positives = 60/113 (53%), Gaps = 2/113 (1%) Frame = +2 Query: 29 EDSPLKATDFGLSVFFKPGEQFR-DLVGSAYYVAPEVLKRR-YGAEADIWSAGVILYILL 202 E+ +K TDFGLS E+ G+ Y+APEV+ R+ + AD WS GV+++ +L Sbjct: 197 EEGHIKLTDFGLSKEAIDHEKKAYSFCGTVEYMAPEVVNRQGHTHSADWWSYGVLMFEML 256 Query: 203 SGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERL 361 +G PF ++ + +LK + +S A+ L++ + +++P RL Sbjct: 257 TGSLPFQGKDRKETMTLILKAKLGMPQ----FLSTEAQSLLRALFKRNPANRL 305
>MEK1_SCHPO (Q10292) Meiosis-specific serine/threonine-protein kinase mek1 (EC| 2.7.11.1) Length = 445 Score = 92.0 bits (227), Expect = 1e-18 Identities = 51/150 (34%), Positives = 77/150 (51%), Gaps = 12/150 (8%) Frame = +2 Query: 50 TDFGLSVFFKPGEQFRDLVGSAYYVAPEV--LKRR----------YGAEADIWSAGVILY 193 TDFG++ + G++ VG+ Y APE+ LK R YG E D+WS GVI++ Sbjct: 302 TDFGVARCMQKGKRLSTFVGTPEYTAPEIQRLKGRSQVEKENSSGYGKEVDLWSLGVIMF 361 Query: 194 ILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAE 373 +LLSG P +A D V + +DF W S+S AKDL+ +L+ +P +R T + Sbjct: 362 LLLSGNSPSFA-------DGVKEKQVDFRDPVWKSVSRQAKDLISNLLKTNPPDRFTVKQ 414 Query: 374 ILNHPWIREDGEAPDKPLDITVISRMKQFR 463 L+HPW K + ++ +K R Sbjct: 415 CLSHPWFARHSSRLTKLYETRILKPLKHSR 444
>MAPK5_MOUSE (O54992) MAP kinase-activated protein kinase 5 (EC 2.7.11.1)| (MAPK-activated protein kinase 5) (MAPKAP kinase 5) Length = 473 Score = 92.0 bits (227), Expect = 1e-18 Identities = 60/188 (31%), Positives = 96/188 (51%), Gaps = 33/188 (17%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVG---SAYYVAPEVLKRR-------- 148 EN LF + D+P+K DFG F +Q DL+ + YYVAP+VL+ + Sbjct: 152 ENLLFKDNSLDAPVKLCDFG----FAKVDQ-GDLMTPQFTPYYVAPQVLEAQRRHQKEKS 206 Query: 149 -----------YGAEADIWSAGVILYILLSGVPPFWAENE-----EGIFDAVLKGHIDFS 280 Y D+WS GVI+Y++L G PPF++++ + + ++ G +F Sbjct: 207 GIIPTSPTPYTYNKSCDLWSLGVIIYVMLCGYPPFYSKHHSRTIPKDMRKKIMTGSFEFP 266 Query: 281 SDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHPWIRE----DGEAPDKPL--DITVI 442 + W IS AKD+V+++L+ P+ERLT +L+HPW+ D P L D V+ Sbjct: 267 EEEWSQISEMAKDVVRKLLKVKPEERLTIEGVLDHPWLNSTEALDNVLPSAQLMMDKAVV 326 Query: 443 SRMKQFRA 466 + ++Q A Sbjct: 327 AGIQQAHA 334
>LOK_DROME (O61267) Ovarian-specific serine/threonine-protein kinase Lok (EC| 2.7.11.1) (Protein loki) (dMNK) Length = 476 Score = 92.0 bits (227), Expect = 1e-18 Identities = 51/137 (37%), Positives = 72/137 (52%), Gaps = 4/137 (2%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVL----KRRYGAEADI 169 +N L E++ LK +DFGLS F + R L G+ YVAPEVL + Y + DI Sbjct: 307 DNVLLETNDEETLLKVSDFGLSKFVQKDSVMRTLCGTPLYVAPEVLITGGREAYTKKVDI 366 Query: 170 WSAGVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDP 349 WS GV+L+ LSG PF E + KG + W S+S AK L+ +ML DP Sbjct: 367 WSLGVVLFTCLSGTLPFSDEYGTPAAQQIKKGRFAYGHPSWKSVSQRAKLLINQMLIVDP 426 Query: 350 KERLTAAEILNHPWIRE 400 + R + ++L W+R+ Sbjct: 427 ERRPSIDDVLQSSWLRD 443
>MAPK5_HUMAN (Q8IW41) MAP kinase-activated protein kinase 5 (EC 2.7.11.1)| (MAPK-activated protein kinase 5) (MAPKAP kinase 5) (p38-regulated/activated protein kinase) Length = 473 Score = 91.7 bits (226), Expect = 1e-18 Identities = 56/185 (30%), Positives = 90/185 (48%), Gaps = 30/185 (16%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRR----------- 148 EN LF + D+P+K DFG + + + YYVAP+VL+ + Sbjct: 152 ENLLFKDNSLDAPVKLCDFGFAKIDQGDLMTPQF--TPYYVAPQVLEAQRRHQKEKSGII 209 Query: 149 --------YGAEADIWSAGVILYILLSGVPPFWAENEEGIFDA-----VLKGHIDFSSDP 289 Y D+WS GVI+Y++L G PPF++++ ++ G +F + Sbjct: 210 PTSPTPYTYNKSCDLWSLGVIIYVMLCGYPPFYSKHHSRTIPKDMRRKIMTGSFEFPEEE 269 Query: 290 WPSISNGAKDLVKRMLRQDPKERLTAAEILNHPWIRE----DGEAPDKPL--DITVISRM 451 W IS AKD+V+++L+ P+ERLT +L+HPW+ D P L D V++ + Sbjct: 270 WSQISEMAKDVVRKLLKVKPEERLTIEGVLDHPWLNSTEALDNVLPSAQLMMDKAVVAGI 329 Query: 452 KQFRA 466 +Q A Sbjct: 330 QQAHA 334
>KS6A1_MOUSE (P18653) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1)| (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 724 Score = 91.3 bits (225), Expect = 2e-18 Identities = 47/110 (42%), Positives = 65/110 (59%), Gaps = 4/110 (3%) Frame = +2 Query: 110 SAYYVAPEVLKRR-YGAEADIWSAGVILYILLSGVPPFW---AENEEGIFDAVLKGHIDF 277 +A +VAPEVLKR+ Y DIWS G++LY +L+G PF ++ E I + G Sbjct: 566 TANFVAPEVLKRQGYDEGCDIWSLGILLYTMLAGYTPFANGPSDTPEEILTRIGSGKFTL 625 Query: 278 SSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHPWIREDGEAPDKPL 427 S W ++S AKDLV +ML DP +RLTA ++L HPWI + + P L Sbjct: 626 SGGNWNTVSETAKDLVSKMLHVDPHQRLTAKQVLQHPWITQKDKLPQSQL 675 Score = 37.0 bits (84), Expect = 0.044 Identities = 30/113 (26%), Positives = 53/113 (46%), Gaps = 2/113 (1%) Frame = +2 Query: 29 EDSPLKATDFGLSVFFKPGEQFR-DLVGSAYYVAPEVLKRR-YGAEADIWSAGVILYILL 202 E+ +K TDFGLS E+ G+ Y+APEV+ R+ + AD WS GV++ Sbjct: 197 EEGHIKLTDFGLSKEAIDHEKKAYSFCGTVEYMAPEVVNRQGHTHSADWWSYGVLM---- 252 Query: 203 SGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERL 361 ++ + +LK + +S A+ L++ + +++P RL Sbjct: 253 -------GKDRKETMTLILKAKLGMPQ----FLSTEAQSLLRALFKRNPANRL 294
>KS6AA_CHICK (P18652) Ribosomal protein S6 kinase 2 alpha (EC 2.7.11.1)| (Ribosomal protein S6 kinase II alpha) (S6KII-alpha) (P90-RSK) (MAP kinase-activated protein kinase 1) (MAPK-activated protein kinase 1) (MAPKAP kinase 1) (MAPKAPK-1) Length = 752 Score = 91.3 bits (225), Expect = 2e-18 Identities = 49/119 (41%), Positives = 69/119 (57%), Gaps = 4/119 (3%) Frame = +2 Query: 110 SAYYVAPEVLKRR-YGAEADIWSAGVILYILLSGVPPFW---AENEEGIFDAVLKGHIDF 277 +A +VAPEVLKR+ Y DIWS GV+LY +L+G PF ++ E I + G Sbjct: 594 TANFVAPEVLKRQGYDEGCDIWSLGVLLYTMLAGCTPFANGPSDTPEEILTRIGGGKFSV 653 Query: 278 SSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHPWIREDGEAPDKPLDITVISRMK 454 + W +IS+ AKDLV +ML DP +RLTA ++L HPWI + P L+ + +K Sbjct: 654 NGGNWDTISDVAKDLVSKMLHVDPHQRLTAKQVLQHPWITQKDSLPQSQLNYQDVQLVK 712 Score = 55.8 bits (133), Expect = 9e-08 Identities = 39/128 (30%), Positives = 66/128 (51%), Gaps = 7/128 (5%) Frame = +2 Query: 29 EDSPLKATDFGLSVFFKPGEQFR-DLVGSAYYVAPEVLKRR-YGAEADIWSAGVILYILL 202 E+ +K TDFGLS E+ G+ Y+APEV+ R+ + AD WS GV+++ +L Sbjct: 215 EEGHIKLTDFGLSKEAIDHEKKAYSFCGTVEYMAPEVVNRQGHSHSADWWSYGVLMFEML 274 Query: 203 SGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERL-----TA 367 +G PF ++ + +LK + +S A+ L++ + +++P RL A Sbjct: 275 TGSLPFQGKDRKETMTLILKAKLGMPQ----FLSAEAQSLLRALFKRNPANRLGSGPDGA 330 Query: 368 AEILNHPW 391 EI HP+ Sbjct: 331 EEIKRHPF 338
>KS6A3_MOUSE (P18654) Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1)| (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (MAP kinase-activated protein kinase 1b) (MAPKAPK1B) Length = 740 Score = 91.3 bits (225), Expect = 2e-18 Identities = 51/111 (45%), Positives = 66/111 (59%), Gaps = 4/111 (3%) Frame = +2 Query: 110 SAYYVAPEVLKRR-YGAEADIWSAGVILYILLSGVPPFWA---ENEEGIFDAVLKGHIDF 277 +A +VAPEVLKR+ Y A DIWS GV+LY +L+G PF + E I + G Sbjct: 581 TANFVAPEVLKRQGYDAACDIWSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSL 640 Query: 278 SSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHPWIREDGEAPDKPLD 430 S W S+S+ AKDLV +ML DP +RLTAA +L HPWI + P L+ Sbjct: 641 SGGYWNSVSDTAKDLVSKMLHVDPHQRLTAALVLRHPWIVHWDQLPQYQLN 691 Score = 55.5 bits (132), Expect = 1e-07 Identities = 36/115 (31%), Positives = 61/115 (53%), Gaps = 2/115 (1%) Frame = +2 Query: 29 EDSPLKATDFGLSVFFKPGEQFR-DLVGSAYYVAPEVLKRR-YGAEADIWSAGVILYILL 202 E+ +K TDFGLS E+ G+ Y+APEV+ RR + AD WS GV+++ +L Sbjct: 203 EEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNRRGHTQSADWWSFGVLMFEML 262 Query: 203 SGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTA 367 +G PF ++ + +LK + +S A+ L++ + +++P RL A Sbjct: 263 TGTLPFQGKDRKETMTMILKAKLGMPQ----FLSPEAQSLLRMLFKRNPANRLGA 313
>KS6A3_HUMAN (P51812) Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1)| (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protei Length = 740 Score = 91.3 bits (225), Expect = 2e-18 Identities = 51/111 (45%), Positives = 66/111 (59%), Gaps = 4/111 (3%) Frame = +2 Query: 110 SAYYVAPEVLKRR-YGAEADIWSAGVILYILLSGVPPFWA---ENEEGIFDAVLKGHIDF 277 +A +VAPEVLKR+ Y A DIWS GV+LY +L+G PF + E I + G Sbjct: 581 TANFVAPEVLKRQGYDAACDIWSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSL 640 Query: 278 SSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHPWIREDGEAPDKPLD 430 S W S+S+ AKDLV +ML DP +RLTAA +L HPWI + P L+ Sbjct: 641 SGGYWNSVSDTAKDLVSKMLHVDPHQRLTAALVLRHPWIVHWDQLPQYQLN 691 Score = 55.5 bits (132), Expect = 1e-07 Identities = 36/115 (31%), Positives = 61/115 (53%), Gaps = 2/115 (1%) Frame = +2 Query: 29 EDSPLKATDFGLSVFFKPGEQFR-DLVGSAYYVAPEVLKRR-YGAEADIWSAGVILYILL 202 E+ +K TDFGLS E+ G+ Y+APEV+ RR + AD WS GV+++ +L Sbjct: 203 EEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNRRGHTQSADWWSFGVLMFEML 262 Query: 203 SGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTA 367 +G PF ++ + +LK + +S A+ L++ + +++P RL A Sbjct: 263 TGTLPFQGKDRKETMTMILKAKLGMPQ----FLSPEAQSLLRMLFKRNPANRLGA 313
>KS6A_CAEEL (Q21734) Putative ribosomal protein S6 kinase alpha (EC 2.7.11.1)| Length = 784 Score = 90.9 bits (224), Expect = 3e-18 Identities = 64/193 (33%), Positives = 97/193 (50%), Gaps = 9/193 (4%) Frame = +2 Query: 5 NFLFLNKRED-SPLKATDFGLSVFFKPGEQFRDLVGS----AYYVAPEVLKRR-YGAEAD 166 N LF K D S L+ DFG F K ++ + A +VAPEVL+++ Y D Sbjct: 577 NILFALKDGDPSSLRIVDFG---FAKQSRAENGMLMTPCYTAQFVAPEVLRKQGYDRSCD 633 Query: 167 IWSAGVILYILLSGVPPFWA---ENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRML 337 +WS GV+L+ +L+G PF + + I V G I + W +IS+ AKDLV++ML Sbjct: 634 VWSLGVLLHTMLTGCTPFAMGPNDTPDQILQRVGDGKISMTHPVWDTISDEAKDLVRKML 693 Query: 338 RQDPKERLTAAEILNHPWIREDGEAPDKPLDITVISRMKQFRAMNKLKKVALKIVAESLS 517 DP R+TA + L H WI + PD+P+ + + KVAL+ ++++ Sbjct: 694 DVDPNRRVTAKQALQHKWIGQKEALPDRPIQSEQVGELDMQNV-----KVALEQTYKAIA 748 Query: 518 EEEIVGLREMFKS 556 V LR + S Sbjct: 749 SAPSVQLRPVGSS 761 Score = 54.3 bits (129), Expect = 3e-07 Identities = 34/114 (29%), Positives = 58/114 (50%), Gaps = 2/114 (1%) Frame = +2 Query: 32 DSPLKATDFGLSVFFKPGEQFR-DLVGSAYYVAPEVLKRR-YGAEADIWSAGVILYILLS 205 D +K TDFGLS E+ G+ Y+APEV+ RR + AD WS GV+++ +L+ Sbjct: 240 DGHIKVTDFGLSKEAIDSEKKTYSFCGTVEYMAPEVINRRGHSMAADFWSLGVLMFEMLT 299 Query: 206 GVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTA 367 G PF + +LK + ++ A+ L++ + +++ + RL A Sbjct: 300 GHLPFQGRDRNDTMTQILKAKLSMPH----FLTQEAQSLLRALFKRNSQNRLGA 349
>KS6A1_HUMAN (Q15418) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1)| (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 735 Score = 90.9 bits (224), Expect = 3e-18 Identities = 46/110 (41%), Positives = 65/110 (59%), Gaps = 4/110 (3%) Frame = +2 Query: 110 SAYYVAPEVLKRR-YGAEADIWSAGVILYILLSGVPPFW---AENEEGIFDAVLKGHIDF 277 +A +VAPEVLKR+ Y DIWS G++LY +L+G PF ++ E I + G Sbjct: 577 TANFVAPEVLKRQGYDEGCDIWSLGILLYTMLAGYTPFANGPSDTPEEILTRIGSGKFTL 636 Query: 278 SSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHPWIREDGEAPDKPL 427 S W ++S AKDLV +ML DP +RLTA ++L HPW+ + + P L Sbjct: 637 SGGNWNTVSETAKDLVSKMLHVDPHQRLTAKQVLQHPWVTQKDKLPQSQL 686 Score = 53.5 bits (127), Expect = 4e-07 Identities = 34/113 (30%), Positives = 60/113 (53%), Gaps = 2/113 (1%) Frame = +2 Query: 29 EDSPLKATDFGLSVFFKPGEQFR-DLVGSAYYVAPEVLKRR-YGAEADIWSAGVILYILL 202 E+ +K TDFGLS E+ G+ Y+APEV+ R+ + AD WS GV+++ +L Sbjct: 197 EEGHIKLTDFGLSKEAIDHEKKAYSFCGTVEYMAPEVVNRQGHSHSADWWSYGVLMFEML 256 Query: 203 SGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERL 361 +G PF ++ + +LK + +S A+ L++ + +++P RL Sbjct: 257 TGSLPFQGKDRKETMTLILKAKLGMPQ----FLSTEAQSLLRALFKRNPANRL 305
>KS6A2_MOUSE (Q9WUT3) Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1)| (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (Protein-tyrosine kinase Mpk-9) (MAP kinase-activated protein kinase 1c) (M Length = 733 Score = 90.5 bits (223), Expect = 3e-18 Identities = 46/99 (46%), Positives = 63/99 (63%), Gaps = 4/99 (4%) Frame = +2 Query: 110 SAYYVAPEVLKRR-YGAEADIWSAGVILYILLSGVPPFWA---ENEEGIFDAVLKGHIDF 277 +A +VAPEVLKR+ Y A D+WS G++LY +L+G PF + E I + G Sbjct: 574 TANFVAPEVLKRQGYDAACDVWSLGILLYTMLAGFTPFANGPDDTPEEILARIGSGKYAL 633 Query: 278 SSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHPWI 394 S W SIS+ AKD+V +ML DP++RLTA ++L HPWI Sbjct: 634 SGGNWDSISDAAKDVVSKMLHVDPQQRLTAVQVLKHPWI 672 Score = 55.5 bits (132), Expect = 1e-07 Identities = 39/128 (30%), Positives = 66/128 (51%), Gaps = 7/128 (5%) Frame = +2 Query: 29 EDSPLKATDFGLSVFFKPGEQFR-DLVGSAYYVAPEVLKRR-YGAEADIWSAGVILYILL 202 E+ +K TDFGLS ++ G+ Y+APEV+ RR + AD WS GV+++ +L Sbjct: 194 EEGHIKITDFGLSKEATDHDKRAYSFCGTIEYMAPEVVNRRGHTQSADWWSFGVLMFEML 253 Query: 203 SGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAA---- 370 +G PF ++ + +LK + +S A+ L++ + +++P RL A Sbjct: 254 TGSLPFQGKDRKETMALILKAKLGMPQ----FLSAEAQSLLRALFKRNPCNRLGAGVDGV 309 Query: 371 -EILNHPW 391 EI HP+ Sbjct: 310 EEIKRHPF 317
>KS6A2_HUMAN (Q15349) Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1)| (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (MAP kinase-activated protein kinase 1c) (MAPKAPK1C) Length = 733 Score = 89.7 bits (221), Expect = 6e-18 Identities = 51/125 (40%), Positives = 71/125 (56%), Gaps = 7/125 (5%) Frame = +2 Query: 41 LKATDFGLSVFFKPGEQFRDLVGSAY---YVAPEVLKRR-YGAEADIWSAGVILYILLSG 208 ++ DFG + + G L+ Y +VAPEVLKR+ Y A DIWS G++LY +L+G Sbjct: 550 IRVCDFGFAKQLRAGNGL--LMTPCYTANFVAPEVLKRQGYDAACDIWSLGILLYTMLAG 607 Query: 209 VPPFWA---ENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEIL 379 PF + E I + G S W SIS+ AKD+V +ML DP +RLTA ++L Sbjct: 608 FTPFANGPDDTPEEILARIGSGKYALSGGNWDSISDAAKDVVSKMLHVDPHQRLTAMQVL 667 Query: 380 NHPWI 394 HPW+ Sbjct: 668 KHPWV 672 Score = 57.0 bits (136), Expect = 4e-08 Identities = 39/128 (30%), Positives = 66/128 (51%), Gaps = 7/128 (5%) Frame = +2 Query: 29 EDSPLKATDFGLSV-FFKPGEQFRDLVGSAYYVAPEVLKRR-YGAEADIWSAGVILYILL 202 E+ +K TDFGLS ++ G+ Y+APEV+ RR + AD WS GV+++ +L Sbjct: 194 EEGHIKITDFGLSKEAIDHDKRAYSFCGTIEYMAPEVVNRRGHTQSADWWSFGVLMFEML 253 Query: 203 SGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAA---- 370 +G PF ++ + +LK + +S A+ L++ + +++P RL A Sbjct: 254 TGSLPFQGKDRKETMALILKAKLGMPQ----FLSGEAQSLLRALFKRNPCNRLGAGIDGV 309 Query: 371 -EILNHPW 391 EI HP+ Sbjct: 310 EEIKRHPF 317
>KIN10_ARATH (Q38997) SNF1-related protein kinase catalytic alpha subunit KIN10| (EC 2.7.11.1) (AKIN10) (AKIN alpha2) Length = 535 Score = 89.4 bits (220), Expect = 7e-18 Identities = 51/121 (42%), Positives = 65/121 (53%), Gaps = 2/121 (1%) Frame = +2 Query: 41 LKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRRY--GAEADIWSAGVILYILLSGVP 214 +K DFGLS + G + GS Y APEV+ + G E D+WS GVILY LL G Sbjct: 179 VKIADFGLSNIMRDGHFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYALLCGTL 238 Query: 215 PFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHPWI 394 PF EN +F + G S +S GA+DL+ RML DP +R+T EI HPW Sbjct: 239 PFDDENIPNLFKKIKGGIYTLPSH----LSPGARDLIPRMLVVDPMKRVTIPEIRQHPWF 294 Query: 395 R 397 + Sbjct: 295 Q 295
>CDR1_SCHPO (P07334) Mitosis inducer protein kinase cdr1 (EC 2.7.11.1) (Protein| kinase nim1) Length = 593 Score = 88.6 bits (218), Expect = 1e-17 Identities = 61/192 (31%), Positives = 94/192 (48%), Gaps = 15/192 (7%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRR--YGAEADIWS 175 EN L K + +K DFG++ + GS +Y+APE++ + GA AD+WS Sbjct: 132 ENILI--KVNEQQIKIADFGMATVEPNDSCLENYCGSLHYLAPEIVSHKPYRGAPADVWS 189 Query: 176 AGVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKE 355 GVILY LLS PF +N + I++ + G D S SIS+ A+DL+ RML +P Sbjct: 190 CGVILYSLLSNKLPFGGQNTDVIYNKIRHGAYDLPS----SISSAAQDLLHRMLDVNPST 245 Query: 356 RLTAAEILNHPWI-------REDGEAPDKP------LDITVISRMKQFRAMNKLKKVALK 496 R+T E+ +HP++ D P P +D V+ M + KKV + Sbjct: 246 RITIPEVFSHPFLMGCTSLSSMDSTTPPTPSLSIDEIDPLVVDCMCVLWKKSSSKKVVRR 305 Query: 497 IVAESLSEEEIV 532 + ++E+ V Sbjct: 306 LQQRDDNDEKYV 317
>IPL1_ASHGO (Q755C4) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 367 Score = 87.8 bits (216), Expect = 2e-17 Identities = 43/125 (34%), Positives = 73/125 (58%), Gaps = 1/125 (0%) Frame = +2 Query: 32 DSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLK-RRYGAEADIWSAGVILYILLSG 208 ++ +K TDFG SV G + + L G+ Y++PE+++ R Y + D+W+ GV+ Y LL G Sbjct: 243 NNTIKLTDFGWSVITPKGSKRKTLCGTVDYLSPELIRSREYNEKVDVWALGVLTYELLVG 302 Query: 209 VPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHP 388 PPF E++E + +LK ++ F + A+ L+ R+L DP +R+ E+ HP Sbjct: 303 SPPFEEESKELTYKRILKRNLIFPD----HVDTEARHLISRLLEYDPGDRIPLKEVKKHP 358 Query: 389 WIRED 403 WI ++ Sbjct: 359 WIEKN 363
>KIN2_YEAST (P13186) Serine/threonine-protein kinase KIN2 (EC 2.7.11.1)| Length = 1147 Score = 87.4 bits (215), Expect = 3e-17 Identities = 58/197 (29%), Positives = 97/197 (49%), Gaps = 14/197 (7%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRR--YGAEADIWS 175 EN + + E +K DFGLS F +Q GS Y+ APE+LK + G E DIWS Sbjct: 252 ENIMISSSGE---IKIIDFGLSNIFDYRKQLHTFCGSLYFAAPELLKAQPYTGPEVDIWS 308 Query: 176 AGVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKE 355 G++LY+L+ G PF EN + + + KG +D+ S +S L+ RM+ DP Sbjct: 309 FGIVLYVLVCGKVPFDDENSSILHEKIKKGKVDYPS----HLSIEVISLLTRMIVVDPLR 364 Query: 356 RLTAAEILNHPWIRE--DGEAPD----------KPLDITVISRMKQFRAMNKLKKVALKI 499 R T ++ HPW+ D +AP + +D V+ M + ++ ++ + Sbjct: 365 RATLKNVVEHPWMNRGYDFKAPSYVPNRVPLTPEMIDSQVLKEMYRLEFIDDIEDTRRSL 424 Query: 500 VAESLSEEEIVGLREMF 550 + ++E+E + L + + Sbjct: 425 I-RLVTEKEYIQLSQEY 440
>MELK_MOUSE (Q61846) Maternal embryonic leucine zipper kinase (EC 2.7.11.1)| (Protein kinase PK38) (mPK38) Length = 643 Score = 87.0 bits (214), Expect = 4e-17 Identities = 50/142 (35%), Positives = 81/142 (57%), Gaps = 4/142 (2%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQF--RDLVGSAYYVAPEVL--KRRYGAEADI 169 EN LF E+ LK DFGL K + + + GS Y APE++ K G+EAD+ Sbjct: 136 ENLLF---DENHKLKLIDFGLCAKPKGNKDYHLQTCCGSLAYAAPELIQGKSYLGSEADV 192 Query: 170 WSAGVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDP 349 WS G++LY+L+ G PF +N ++ +++G + W +S + L+++ML+ DP Sbjct: 193 WSMGILLYVLMCGFLPFDDDNVMALYKKIMRG--KYEVPKW--LSPSSILLLQQMLQVDP 248 Query: 350 KERLTAAEILNHPWIREDGEAP 415 K+R++ +LNHPW+ +D P Sbjct: 249 KKRISMRNLLNHPWVMQDYSCP 270
>KS6A6_HUMAN (Q9UK32) Ribosomal protein S6 kinase alpha-6 (EC 2.7.11.1) (S6K-alpha| 6) (90 kDa ribosomal protein S6 kinase 6) (p90-RSK 6) (Ribosomal S6 kinase 4) (RSK-4) (pp90RSK4) Length = 745 Score = 86.7 bits (213), Expect = 5e-17 Identities = 54/159 (33%), Positives = 79/159 (49%), Gaps = 7/159 (4%) Frame = +2 Query: 110 SAYYVAPEVLKRR-YGAEADIWSAGVILYILLSGVPPFWA---ENEEGIFDAVLKGHIDF 277 +A +VAPEVL ++ Y A DIWS GV+ Y +L+G PF + E I + G Sbjct: 585 TANFVAPEVLMQQGYDAACDIWSLGVLFYTMLAGYTPFANGPNDTPEEILLRIGNGKFSL 644 Query: 278 SSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHPWIREDGEAPD---KPLDITVISR 448 S W +IS+GAKDL+ ML DP +R TA +IL H WI + P+ K D++ + + Sbjct: 645 SGGNWDNISDGAKDLLSHMLHMDPHQRYTAEQILKHSWITHRDQLPNDQPKRNDVSHVVK 704 Query: 449 MKQFRAMNKLKKVALKIVAESLSEEEIVGLREMFKSLDT 565 + L + V E ++ + R M K T Sbjct: 705 GAMVATYSALTHKTFQPVLEPVAASSLAQRRSMKKRTST 743 Score = 54.3 bits (129), Expect = 3e-07 Identities = 34/109 (31%), Positives = 58/109 (53%), Gaps = 2/109 (1%) Frame = +2 Query: 41 LKATDFGLSVFFKPGEQFR-DLVGSAYYVAPEVLKRR-YGAEADIWSAGVILYILLSGVP 214 +K TDFGLS E+ G+ Y+APEV+ RR + AD WS GV+++ +L+G Sbjct: 212 IKLTDFGLSKESVDQEKKAYSFCGTVEYMAPEVVNRRGHSQSADWWSYGVLMFEMLTGTL 271 Query: 215 PFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERL 361 PF ++ + +LK + +S A+ L++ + +++P RL Sbjct: 272 PFQGKDRNETMNMILKAKLGMPQ----FLSAEAQSLLRMLFKRNPANRL 316
>DUN1_YEAST (P39009) DNA damage response protein kinase DUN1 (EC 2.7.11.1)| Length = 513 Score = 86.7 bits (213), Expect = 5e-17 Identities = 48/125 (38%), Positives = 67/125 (53%), Gaps = 2/125 (1%) Frame = +2 Query: 32 DSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVL-KRRYGAEADIWSAGVILYILLSG 208 D +K DFGL+ F + L G+ YVAPEVL K+ Y ++ D+WSAGVILY+ L G Sbjct: 358 DIQVKIADFGLAKFTGEMQFTNTLCGTPSYVAPEVLTKKGYTSKVDLWSAGVILYVCLCG 417 Query: 209 VPPFWAE-NEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNH 385 PPF + + + +L+ F S W I + L+ +L +P ER E LNH Sbjct: 418 FPPFSDQLGPPSLKEQILQAKYAFYSPYWDKIDDSVLHLISNLLVLNPDERYNIDEALNH 477 Query: 386 PWIRE 400 PW + Sbjct: 478 PWFND 482
>MELK_HUMAN (Q14680) Maternal embryonic leucine zipper kinase (EC 2.7.11.1)| (hMELK) (Protein kinase PK38) (hPK38) Length = 651 Score = 86.7 bits (213), Expect = 5e-17 Identities = 52/142 (36%), Positives = 80/142 (56%), Gaps = 4/142 (2%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQF--RDLVGSAYYVAPEVL--KRRYGAEADI 169 EN LF E LK DFGL K + + + GS Y APE++ K G+EAD+ Sbjct: 136 ENLLF---DEYHKLKLIDFGLCAKPKGNKDYHLQTCCGSLAYAAPELIQGKSYLGSEADV 192 Query: 170 WSAGVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDP 349 WS G++LY+L+ G PF +N ++ +++G D W +S + L+++ML+ DP Sbjct: 193 WSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYDVPK--W--LSPSSILLLQQMLQVDP 248 Query: 350 KERLTAAEILNHPWIREDGEAP 415 K+R++ +LNHPWI +D P Sbjct: 249 KKRISMKNLLNHPWIMQDYNYP 270
>KCC2_SCHPO (O42844) Calcium/calmodulin-dependent protein kinase type II (EC| 2.7.11.17) (CAM kinase II) Length = 504 Score = 86.3 bits (212), Expect = 6e-17 Identities = 38/105 (36%), Positives = 60/105 (57%), Gaps = 1/105 (0%) Frame = +2 Query: 107 GSAYYVAPEVLKRR-YGAEADIWSAGVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSS 283 G+ Y APE++ Y D+W+ G +L+ +L G PPF+ EN + + V+ G +F S Sbjct: 255 GTVGYAAPEIVNDELYSKNVDMWAMGCVLHTMLCGFPPFFDENIKDLASKVVNGEFEFLS 314 Query: 284 DPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHPWIREDGEAPD 418 W IS+ AKDL+ +L DP+ER + HPWI+ + + P+ Sbjct: 315 PWWDDISDSAKDLITHLLTVDPRERYDIHQFFQHPWIKGESKMPE 359
>KCC1_METAN (O14408) Calcium/calmodulin-dependent protein kinase (EC 2.7.11.17)| Length = 382 Score = 86.3 bits (212), Expect = 6e-17 Identities = 50/164 (30%), Positives = 83/164 (50%), Gaps = 2/164 (1%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQ-FRDLVGSAYYVAPEVLKRR-YGAEADIWS 175 EN L++ + DS L DFG++ E+ + GS Y APEV++++ +G D+WS Sbjct: 146 ENLLYVTRDPDSDLVLADFGITKTLDIKEETLTTMAGSFGYAAPEVMEQKGHGKPVDMWS 205 Query: 176 AGVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKE 355 GVI Y LL G PF +EN + + F W +S AKD + +L +P++ Sbjct: 206 MGVITYTLLCGYSPFRSENLRDLLRECTAAPVPFHERYWKDVSQDAKDFILVLLVPEPEK 265 Query: 356 RLTAAEILNHPWIREDGEAPDKPLDITVISRMKQFRAMNKLKKV 487 R T+ E L H W+ + D ++ ++ +R +L++V Sbjct: 266 RWTSKEALGHIWL-----SGKNATDHNLLPELEAYRRRARLRRV 304
>MYLK2_HUMAN (Q9H1R3) Myosin light chain kinase 2, skeletal/cardiac muscle (EC| 2.7.11.18) (MLCK2) Length = 595 Score = 86.3 bits (212), Expect = 6e-17 Identities = 46/137 (33%), Positives = 79/137 (57%), Gaps = 1/137 (0%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKR-RYGAEADIWSA 178 EN L +N +K DFGL+ + P E+ + G+ +++PEV+ + + D+WS Sbjct: 409 ENILCVNTTGHL-VKIIDFGLARRYNPNEKLKVNFGTPEFLSPEVVNYDQISDKTDMWSM 467 Query: 179 GVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKER 358 GVI Y+LLSG+ PF +++ + VL G+ F + + ++S+ AKD V ++ +D + R Sbjct: 468 GVITYMLLSGLSPFLGDDDTETLNNVLSGNWYFDEETFEAVSDEAKDFVSNLIVKDQRAR 527 Query: 359 LTAAEILNHPWIREDGE 409 + AA+ L HPW+ E Sbjct: 528 MNAAQCLAHPWLNNLAE 544
>SN1L1_MOUSE (Q60670) Serine/threonine-protein kinase SNF1-like kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase SNF1LK) (HRT-20) (Myocardial SNF1-like kinase) Length = 779 Score = 86.3 bits (212), Expect = 6e-17 Identities = 48/123 (39%), Positives = 66/123 (53%), Gaps = 2/123 (1%) Frame = +2 Query: 41 LKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVL--KRRYGAEADIWSAGVILYILLSGVP 214 +K DFG F+KPGE VGS Y APEV K G + D+WS GV+LY+L+ G Sbjct: 163 IKLADFGFGNFYKPGEPLSTCVGSPPYAAPEVFEGKEYEGPQLDVWSLGVVLYVLVCGSL 222 Query: 215 PFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHPWI 394 PF N + VL+G +S + L++RML DP +R+T A+I H W+ Sbjct: 223 PFDGPNLPTLRQRVLEGRFRIPF----FMSQDCETLIRRMLVVDPAKRITIAQIRQHRWM 278 Query: 395 RED 403 + D Sbjct: 279 QAD 281
>IPL1_CANGA (Q6FV07) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 358 Score = 85.9 bits (211), Expect = 8e-17 Identities = 44/122 (36%), Positives = 71/122 (58%), Gaps = 1/122 (0%) Frame = +2 Query: 32 DSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLK-RRYGAEADIWSAGVILYILLSG 208 D+ +K DFG S+ G + + L G+ Y++PE++ R Y + D+W+ GV+ Y L+ G Sbjct: 234 DNVVKLADFGWSILNPEGSKRKTLCGTIDYLSPEMITPREYDEQVDVWALGVLAYELVVG 293 Query: 209 VPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHP 388 VPPF ++E + +LK ++F SIS AKDL+ ++L D +RL+ + HP Sbjct: 294 VPPFEENSKELTYKRILKCDLNFPE----SISKDAKDLISKLLVTDTTQRLSLTGVKTHP 349 Query: 389 WI 394 WI Sbjct: 350 WI 351
>KS6AA_XENLA (P10665) Ribosomal protein S6 kinase 2 alpha (EC 2.7.11.1)| (Ribosomal protein S6 kinase II alpha) (S6KII-alpha) (P90-RSK) (MAP kinase-activated protein kinase 1) (MAPK-activated protein kinase 1) (MAPKAP kinase 1) (MAPKAPK-1) Length = 733 Score = 85.9 bits (211), Expect = 8e-17 Identities = 51/137 (37%), Positives = 71/137 (51%), Gaps = 9/137 (6%) Frame = +2 Query: 110 SAYYVAPEVLKRR-YGAEADIWSAGVILYILLSGVPPF---WAENEEGIFDAVLKGHIDF 277 +A +VAPEVLKR+ Y DIWS G++LY +L+G PF + E I + G Sbjct: 575 TANFVAPEVLKRQGYDEGCDIWSLGILLYTMLAGYTPFANGLGDTPEEILARIGSGKFTL 634 Query: 278 SSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHPWIREDGEAPDKPLDITVISRMK- 454 W ++S AKDLV RML DP +RLTA ++L H WI + P L+ + +K Sbjct: 635 RGGNWNTVSAAAKDLVSRMLHVDPHKRLTAKQVLQHEWITKRDALPQSQLNRQDVHLVKG 694 Query: 455 ----QFRAMNKLKKVAL 493 + A+N K L Sbjct: 695 AMAATYSALNSSKPTPL 711 Score = 57.0 bits (136), Expect = 4e-08 Identities = 36/116 (31%), Positives = 63/116 (54%), Gaps = 2/116 (1%) Frame = +2 Query: 29 EDSPLKATDFGLSVFFKPGEQFR-DLVGSAYYVAPEVLKRR-YGAEADIWSAGVILYILL 202 E+ +K TDFGLS E+ G+ Y+APEV+ R+ + AD WS GV+++ +L Sbjct: 197 EEGHIKLTDFGLSKEAIDHEKKAYSFCGTVEYMAPEVVNRQGHSHSADWWSYGVLMFEML 256 Query: 203 SGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAA 370 +G PF ++ + +LK + +SN A+ L++ + +++P RL +A Sbjct: 257 TGSLPFQGKDRKETMTLILKAKLGMPQ----FLSNEAQSLLRALFKRNPTNRLGSA 308
>KS6A5_CHICK (Q5F3L1) Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1)| Length = 789 Score = 85.9 bits (211), Expect = 8e-17 Identities = 45/151 (29%), Positives = 78/151 (51%), Gaps = 9/151 (5%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQ-FRDLVGSAYYVAPEVLKRR-YGAEADIWS 175 EN LF ++ ++S +K DFG + P Q + + +Y APE+ Y D+WS Sbjct: 538 ENLLFTDETDNSEIKIIDFGFARLKPPDNQPLKTPCFTLHYAAPELFNHNGYDESCDLWS 597 Query: 176 AGVILYILLSGVPPFWAENEE-------GIFDAVLKGHIDFSSDPWPSISNGAKDLVKRM 334 GVILY +LSG PF ++++ I + KG F + W ++S AK+L++ + Sbjct: 598 LGVILYTMLSGQVPFQSQDKSLTCTSALEIMKKIKKGEFSFEGEAWKNVSEEAKELIQGL 657 Query: 335 LRQDPKERLTAAEILNHPWIREDGEAPDKPL 427 L DP +R+ + + + W+++ + PL Sbjct: 658 LTVDPNKRIKMSSLRYNEWLQDGSQLSSNPL 688 Score = 67.0 bits (162), Expect = 4e-11 Identities = 46/133 (34%), Positives = 71/133 (53%), Gaps = 11/133 (8%) Frame = +2 Query: 32 DSPLKATDFGLSVFFKPGEQFR--DLVGSAYYVAPEVLK---RRYGAEADIWSAGVILYI 196 D + TDFGLS F E R G+ Y+AP++++ + D WS GV++Y Sbjct: 178 DGHVVLTDFGLSKEFLTDENERAYSFCGTIEYMAPDIVRGGDTGHDKAVDWWSVGVLMYE 237 Query: 197 LLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWP-SISNGAKDLVKRMLRQDPKERL---- 361 LL+G PF + E+ A + I S P+P +S +KD+++R+L +DPK+RL Sbjct: 238 LLTGASPFTVDGEKN-SQAEISRRILKSEPPYPQEMSALSKDIIQRLLMKDPKKRLGCGP 296 Query: 362 -TAAEILNHPWIR 397 A EI HP+ + Sbjct: 297 TDADEIKQHPFFQ 309
>ICL1_KLULA (Q6CWQ4) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 361 Score = 85.9 bits (211), Expect = 8e-17 Identities = 42/122 (34%), Positives = 77/122 (63%), Gaps = 1/122 (0%) Frame = +2 Query: 32 DSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLK-RRYGAEADIWSAGVILYILLSG 208 ++ +K TDFG SV+ + G++ + L G+ Y++PE++K R Y + D+W+ GV+ Y LL G Sbjct: 234 NNTIKLTDFGWSVYNEDGQKRKTLCGTIDYLSPELIKSREYNNKVDVWALGVLTYELLVG 293 Query: 209 VPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHP 388 PPF + +E + +L+ + F ++S A+DL+ R+L+ +P +R+ +E+ +H Sbjct: 294 SPPFEEDTKEMTYRRILRCDLKFPL----NVSPQARDLIVRLLQFEPSKRIPLSEVKSHA 349 Query: 389 WI 394 WI Sbjct: 350 WI 351
>KS6A5_HUMAN (O75582) Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1) (Nuclear| mitogen-and stress-activated protein kinase 1) (90 kDa ribosomal protein S6 kinase 5) (RSK-like protein kinase) (RSKL) Length = 802 Score = 85.9 bits (211), Expect = 8e-17 Identities = 47/151 (31%), Positives = 77/151 (50%), Gaps = 9/151 (5%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQ-FRDLVGSAYYVAPEVLKRR-YGAEADIWS 175 EN LF ++ ++ +K DFG + P Q + + +Y APE+L + Y D+WS Sbjct: 548 ENLLFTDENDNLEIKIIDFGFARLKPPDNQPLKTPCFTLHYAAPELLNQNGYDESCDLWS 607 Query: 176 AGVILYILLSGVPPFWAENEE-------GIFDAVLKGHIDFSSDPWPSISNGAKDLVKRM 334 GVILY +LSG PF + + I + KG F + W ++S AKDL++ + Sbjct: 608 LGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFEGEAWKNVSQEAKDLIQGL 667 Query: 335 LRQDPKERLTAAEILNHPWIREDGEAPDKPL 427 L DP +RL + + + W+++ + PL Sbjct: 668 LTVDPNKRLKMSGLRYNEWLQDGSQLSSNPL 698 Score = 63.9 bits (154), Expect = 3e-10 Identities = 42/110 (38%), Positives = 62/110 (56%), Gaps = 6/110 (5%) Frame = +2 Query: 50 TDFGLSVFFKPGEQFR--DLVGSAYYVAPEVLK---RRYGAEADIWSAGVILYILLSGVP 214 TDFGLS F E R G+ Y+AP++++ + D WS GV++Y LL+G Sbjct: 194 TDFGLSKEFVADETERAYSFCGTIEYMAPDIVRGGDSGHDKAVDWWSLGVLMYELLTGAS 253 Query: 215 PFWAENEEGIFDAVLKGHIDFSSDPWP-SISNGAKDLVKRMLRQDPKERL 361 PF + E+ A + I S P+P +S AKDL++R+L +DPK+RL Sbjct: 254 PFTVDGEKN-SQAEISRRILKSEPPYPQEMSALAKDLIQRLLMKDPKKRL 302
>KS6A5_MOUSE (Q8C050) Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1) (Nuclear| mitogen-and stress-activated protein kinase 1) (90 kDa ribosomal protein S6 kinase 5) (RSK-like protein kinase) (RLSK) Length = 863 Score = 85.5 bits (210), Expect = 1e-16 Identities = 47/151 (31%), Positives = 76/151 (50%), Gaps = 9/151 (5%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQ-FRDLVGSAYYVAPEVLKRR-YGAEADIWS 175 EN LF ++ ++ +K DFG + P Q + + +Y APE+L Y D+WS Sbjct: 612 ENLLFTDENDNLEIKVIDFGFARLKPPDNQPLKTPCFTLHYAAPELLTHNGYDESCDLWS 671 Query: 176 AGVILYILLSGVPPFWAENEE-------GIFDAVLKGHIDFSSDPWPSISNGAKDLVKRM 334 GVILY +LSG PF + + I + KG F + W ++S AKDL++ + Sbjct: 672 LGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFEGEAWKNVSQEAKDLIQGL 731 Query: 335 LRQDPKERLTAAEILNHPWIREDGEAPDKPL 427 L DP +RL + + + W+++ + PL Sbjct: 732 LTVDPNKRLKMSGLRYNEWLQDGSQLSSNPL 762 Score = 64.7 bits (156), Expect = 2e-10 Identities = 46/123 (37%), Positives = 66/123 (53%), Gaps = 11/123 (8%) Frame = +2 Query: 50 TDFGLSVFFKPGEQFR--DLVGSAYYVAPEVLK---RRYGAEADIWSAGVILYILLSGVP 214 TDFGLS F E R G+ Y+AP++++ + D WS GV++Y LL+G Sbjct: 193 TDFGLSKEFVADETERAYSFCGTIEYMAPDIVRGGDSGHDKAVDWWSLGVLMYELLTGAS 252 Query: 215 PFWAENEEGIFDAVLKGHIDFSSDPWP-SISNGAKDLVKRMLRQDPKERL-----TAAEI 376 PF + E+ A + I S P+P +S AKDL++R+L +DPK+RL A EI Sbjct: 253 PFTVDGEKN-SQAEISRRILKSEPPYPQEMSTVAKDLLQRLLMKDPKKRLGCGPRDAEEI 311 Query: 377 LNH 385 H Sbjct: 312 KEH 314
>RCK1_YEAST (P38622) Serine/threonine-protein kinase RCK1 (EC 2.7.11.1)| Length = 512 Score = 85.5 bits (210), Expect = 1e-16 Identities = 43/119 (36%), Positives = 68/119 (57%), Gaps = 1/119 (0%) Frame = +2 Query: 41 LKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVL-KRRYGAEADIWSAGVILYILLSGVPP 217 +K DFGL+ + + G+ YVA EV +RY + D+WS G +L+ LL G PP Sbjct: 297 VKLMDFGLAKKLR-NNTAKTPCGTIEYVASEVFTSKRYSMKVDMWSIGCVLFTLLCGYPP 355 Query: 218 FWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHPWI 394 F+ +NE+ + + +G +F + W +IS+GAK+ V +L DP +R + LN PW+ Sbjct: 356 FYEKNEKTLLKKISRGDYEFLAPWWDNISSGAKNAVTHLLEVDPNKRYDIDDFLNDPWL 414
>ATG1_DEBHA (Q6BS08) Serine/threonine-protein kinase ATG1 (EC 2.7.11.1)| (Autophagy-related protein 1) Length = 875 Score = 85.1 bits (209), Expect = 1e-16 Identities = 49/174 (28%), Positives = 85/174 (48%), Gaps = 11/174 (6%) Frame = +2 Query: 41 LKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLK-RRYGAEADIWSAGVILYILLSGVPP 217 LK DFG + F L GS Y+APE+L+ +Y A+AD+WS G +LY + G PP Sbjct: 200 LKIADFGFARFLPSTSMAETLCGSPLYMAPEILRYEKYNAKADLWSVGAVLYEMTVGKPP 259 Query: 218 FWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHPWIR 397 F A+N + + K + + K L++ +L+ +P ER++ E N P I Sbjct: 260 FRADNHVQLLKNIEKSNDRIKFPSAAQVPESLKRLIRSLLKYNPTERVSFNEFFNDPLIV 319 Query: 398 EDGEAPDKPLDIT----------VISRMKQFRAMNKLKKVALKIVAESLSEEEI 529 D E D+PL+ + IS +K + ++ + ++ + S++++ Sbjct: 320 NDLEGNDEPLETSEMDENLFISEYISPIKLSQKSQYIEPITTEVAVKEKSKQDL 373
>KPCD1_MOUSE (Q62101) Serine/threonine-protein kinase D1 (EC 2.7.11.13) (nPKC-D1)| (Protein kinase D) (Protein kinase C mu type) (nPKC-mu) Length = 918 Score = 84.3 bits (207), Expect = 2e-16 Identities = 45/134 (33%), Positives = 72/134 (53%), Gaps = 1/134 (0%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRR-YGAEADIWSA 178 EN L + +K DFG + R +VG+ Y+APEVL+ + Y D+WS Sbjct: 716 ENVLLASADPFPQVKLCDFGFARIIGEKSFRRSVVGTPAYLAPEVLRNKGYNRSLDMWSV 775 Query: 179 GVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKER 358 GVI+Y+ LSG PF +E I D + + +PW IS+ A DL+ +L+ ++R Sbjct: 776 GVIIYVSLSGTFPF--NEDEDIHDQIQNAAFMYPPNPWKEISHEAIDLINNLLQVKMRKR 833 Query: 359 LTAAEILNHPWIRE 400 + + L+HPW+++ Sbjct: 834 YSVDKTLSHPWLQD 847
>KPCD1_HUMAN (Q15139) Serine/threonine-protein kinase D1 (EC 2.7.11.13) (nPKC-D1)| (Protein kinase D) (Protein kinase C mu type) (nPKC-mu) Length = 912 Score = 84.3 bits (207), Expect = 2e-16 Identities = 45/134 (33%), Positives = 72/134 (53%), Gaps = 1/134 (0%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRR-YGAEADIWSA 178 EN L + +K DFG + R +VG+ Y+APEVL+ + Y D+WS Sbjct: 710 ENVLLASADPFPQVKLCDFGFARIIGEKSFRRSVVGTPAYLAPEVLRNKGYNRSLDMWSV 769 Query: 179 GVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKER 358 GVI+Y+ LSG PF +E I D + + +PW IS+ A DL+ +L+ ++R Sbjct: 770 GVIIYVSLSGTFPF--NEDEDIHDQIQNAAFMYPPNPWKEISHEAIDLINNLLQVKMRKR 827 Query: 359 LTAAEILNHPWIRE 400 + + L+HPW+++ Sbjct: 828 YSVDKTLSHPWLQD 841
>SN1L1_RAT (Q9R1U5) Serine/threonine-protein kinase SNF1-like kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase SNF1LK) (Salt-inducible protein kinase) (Protein kinase KID2) Length = 776 Score = 84.3 bits (207), Expect = 2e-16 Identities = 48/123 (39%), Positives = 65/123 (52%), Gaps = 2/123 (1%) Frame = +2 Query: 41 LKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVL--KRRYGAEADIWSAGVILYILLSGVP 214 +K DFG F+KPGE GS Y APEV K G + DIWS GV+LY+L+ G Sbjct: 163 IKLADFGFGNFYKPGEPLSTWCGSPPYAAPEVFEGKEYEGPQLDIWSLGVVLYVLVCGSL 222 Query: 215 PFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHPWI 394 PF N + VL+G +S + L++RML DP +R+T A+I H W+ Sbjct: 223 PFDGPNLPTLRQRVLEGRFRIPF----FMSQDCETLIRRMLVVDPAKRITIAQIRQHRWM 278 Query: 395 RED 403 + D Sbjct: 279 QAD 281
>KS6A5_PONPY (Q5R4K3) Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1)| Length = 802 Score = 84.3 bits (207), Expect = 2e-16 Identities = 47/151 (31%), Positives = 77/151 (50%), Gaps = 9/151 (5%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQ-FRDLVGSAYYVAPEVLKRR-YGAEADIWS 175 EN LF ++ ++ +K DFG + P Q + + +Y APE+L + Y D+WS Sbjct: 548 ENLLFTDENDNLEIKIIDFGFARPKPPDNQPLKTPCFTLHYAAPELLNQNGYDESCDLWS 607 Query: 176 AGVILYILLSGVPPFWAENEE-------GIFDAVLKGHIDFSSDPWPSISNGAKDLVKRM 334 GVILY +LSG PF + + I + KG F + W ++S AKDL++ + Sbjct: 608 LGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFEGEAWKNVSQEAKDLIQGL 667 Query: 335 LRQDPKERLTAAEILNHPWIREDGEAPDKPL 427 L DP +RL + + + W+++ + PL Sbjct: 668 LTVDPNKRLKMSGLRYNEWLQDGSQLSSNPL 698 Score = 62.0 bits (149), Expect = 1e-09 Identities = 41/110 (37%), Positives = 61/110 (55%), Gaps = 6/110 (5%) Frame = +2 Query: 50 TDFGLSVFFKPGEQFR--DLVGSAYYVAPEVLK---RRYGAEADIWSAGVILYILLSGVP 214 TDFGLS F E R G+ Y+AP++++ + D WS GV++Y LL+G Sbjct: 194 TDFGLSKEFVADETERAYSFCGTIEYMAPDIVRGGDSGHDKAVDWWSLGVLMYELLTGAS 253 Query: 215 PFWAENEEGIFDAVLKGHIDFSSDPWP-SISNGAKDLVKRMLRQDPKERL 361 PF + E+ A + I S P+P +S AKDL++ +L +DPK+RL Sbjct: 254 PFTVDGEKN-SQAEISRRILKSEPPYPQEMSALAKDLIQHLLMKDPKKRL 302
>KSG1_SCHPO (Q12701) Serine/threonine-protein kinase ksg1 (EC 2.7.11.1)| Length = 592 Score = 84.3 bits (207), Expect = 2e-16 Identities = 48/106 (45%), Positives = 66/106 (62%), Gaps = 1/106 (0%) Frame = +2 Query: 77 KPGEQFRDLVGSAYYVAPEVLKRRY-GAEADIWSAGVILYILLSGVPPFWAENEEGIFDA 253 KP R VG+A YV+PEVL + G +DIW+ G IL+ +L+G PPF A NE F + Sbjct: 264 KPQAHSRSFVGTARYVSPEVLSDKIAGTASDIWAFGCILFQMLAGKPPFVAGNEYLTFQS 323 Query: 254 VLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHPW 391 +L H+ + P IS+ A DL+K++L DPK+RLT EI HP+ Sbjct: 324 IL--HLSYEIPP--DISDVASDLIKKLLVLDPKDRLTVDEIHQHPF 365
>KPCD2_HUMAN (Q9BZL6) Serine/threonine-protein kinase D2 (EC 2.7.11.13) (nPKC-D2)| Length = 878 Score = 84.3 bits (207), Expect = 2e-16 Identities = 47/134 (35%), Positives = 71/134 (52%), Gaps = 1/134 (0%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRR-YGAEADIWSA 178 EN L + +K DFG + R +VG+ Y+APEVL + Y D+WS Sbjct: 678 ENVLLASADPFPQVKLCDFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQGYNRSLDMWSV 737 Query: 179 GVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKER 358 GVI+Y+ LSG PF +E I D + + + PW IS GA DL+ +L+ ++R Sbjct: 738 GVIMYVSLSGTFPF--NEDEDINDQIQNAAFMYPASPWSHISAGAIDLINNLLQVKMRKR 795 Query: 359 LTAAEILNHPWIRE 400 + + L+HPW++E Sbjct: 796 YSVDKSLSHPWLQE 809
>KIN11_ARATH (P92958) SNF1-related protein kinase catalytic alpha subunit KIN11| (EC 2.7.11.1) (AKIN11) (AKIN alpha1) Length = 512 Score = 84.0 bits (206), Expect = 3e-16 Identities = 49/121 (40%), Positives = 64/121 (52%), Gaps = 2/121 (1%) Frame = +2 Query: 41 LKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRRY--GAEADIWSAGVILYILLSGVP 214 +K DFGLS + G + GS Y APEV+ + G E D+WS GVILY LL G Sbjct: 157 IKIADFGLSNVMRDGHFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYALLCGTL 216 Query: 215 PFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHPWI 394 PF EN +F + G S +S+ A+DL+ RML DP +R+T EI H W Sbjct: 217 PFDDENIPNLFKKIKGGIYTLPS----HLSSEARDLIPRMLIVDPVKRITIPEIRQHRWF 272 Query: 395 R 397 + Sbjct: 273 Q 273
>MYLK2_RABIT (P07313) Myosin light chain kinase 2, skeletal/cardiac muscle (EC| 2.7.11.18) (MLCK2) Length = 607 Score = 83.6 bits (205), Expect = 4e-16 Identities = 45/137 (32%), Positives = 79/137 (57%), Gaps = 1/137 (0%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKR-RYGAEADIWSA 178 EN L +N +K DFGL+ + P E+ + G+ +++PEV+ + + D+WS Sbjct: 421 ENILCVNTTGHL-VKIIDFGLARRYNPNEKLKVNFGTPEFLSPEVVNYDQISDKTDMWSL 479 Query: 179 GVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKER 358 GVI Y+LLSG+ PF +++ + VL G+ F + + ++S+ AKD V ++ ++ R Sbjct: 480 GVITYMLLSGLSPFLGDDDTETLNNVLSGNWYFDEETFEAVSDEAKDFVSNLIVKEQGAR 539 Query: 359 LTAAEILNHPWIREDGE 409 ++AA+ L HPW+ E Sbjct: 540 MSAAQCLAHPWLNNLAE 556
>CIPK1_ORYSA (Q6X4A2) CIPK-like protein 1 (EC 2.7.11.1) (OsCK1)| Length = 449 Score = 83.6 bits (205), Expect = 4e-16 Identities = 51/130 (39%), Positives = 71/130 (54%), Gaps = 5/130 (3%) Frame = +2 Query: 41 LKATDFGLSVF---FKPGEQFRDLVGSAYYVAPEVLKRRY--GAEADIWSAGVILYILLS 205 LK +DFGLS K G+ YVAPEV++ R GA ADIWS GVILY+LL+ Sbjct: 157 LKVSDFGLSALTEQVKADGLLHTTCGTPNYVAPEVIEDRGYDGAAADIWSCGVILYVLLA 216 Query: 206 GVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNH 385 G PF +N ++ + F+ W S GAK L+ R+L +P R+T ++IL Sbjct: 217 GFLPFEDDNIIALYKKI--SEAQFTCPSW--FSTGAKKLITRILDPNPTTRITISQILED 272 Query: 386 PWIREDGEAP 415 PW ++ + P Sbjct: 273 PWFKKGYKPP 282
>MYLK2_MOUSE (Q8VCR8) Myosin light chain kinase 2, skeletal/cardiac muscle (EC| 2.7.11.18) (MLCK2) (Fragment) Length = 240 Score = 83.2 bits (204), Expect = 5e-16 Identities = 45/137 (32%), Positives = 77/137 (56%), Gaps = 1/137 (0%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKR-RYGAEADIWSA 178 EN L +N +K DFGL+ + P E+ + G+ +++PEV+ + + D+WS Sbjct: 54 ENILCVNTTGHL-VKIIDFGLARRYNPNEKLKVNFGTPEFLSPEVVNYDQISDKTDMWSL 112 Query: 179 GVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKER 358 GVI Y+LLSG+ PF +++ + VL + F + + ++S+ AKD V +L +D R Sbjct: 113 GVITYMLLSGLSPFLGDDDTETLNNVLSANWYFDEETFEAVSDEAKDFVSNLLTKDQSAR 172 Query: 359 LTAAEILNHPWIREDGE 409 ++A + L HPW+ E Sbjct: 173 MSAEQCLAHPWLNNLAE 189
>STK6_MOUSE (P97477) Serine/threonine-protein kinase 6 (EC 2.7.11.1)| (Aurora-family kinase 1) (Aurora/IPL1-related kinase 1) (Ipl1- and aurora-related kinase 1) (Aurora-A) (Serine/threonine-protein kinase Ayk1) Length = 395 Score = 83.2 bits (204), Expect = 5e-16 Identities = 47/139 (33%), Positives = 75/139 (53%), Gaps = 1/139 (0%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLK-RRYGAEADIWSA 178 EN L + E LK DFG SV P + + G+ Y+ PE+++ R + + D+WS Sbjct: 251 ENLLLGSNGE---LKIADFGWSVH-APSSRRTTMCGTLDYLPPEMIEGRMHDEKVDLWSL 306 Query: 179 GVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKER 358 GV+ Y L G+PPF A + + + + F ++ GA+DL+ R+L+ + +R Sbjct: 307 GVLCYEFLVGMPPFEAHTYQETYRRISRVEFTFPD----FVTEGARDLISRLLKHNASQR 362 Query: 359 LTAAEILNHPWIREDGEAP 415 LT AE+L HPWI+ + P Sbjct: 363 LTLAEVLEHPWIKANSSKP 381
>KPCD3_MOUSE (Q8K1Y2) Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein| kinase C nu type) (nPKC-nu) Length = 889 Score = 82.8 bits (203), Expect = 7e-16 Identities = 45/134 (33%), Positives = 72/134 (53%), Gaps = 1/134 (0%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRR-YGAEADIWSA 178 EN L + +K DFG + R +VG+ Y+APEVL+ + Y D+WS Sbjct: 702 ENVLLASAEPFPQVKLCDFGFARIIGEKSFRRSVVGTPAYLAPEVLRSKGYNRSLDMWSV 761 Query: 179 GVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKER 358 GVI+Y+ LSG PF +E I D + + +PW IS+ A DL+ +L+ ++R Sbjct: 762 GVIVYVSLSGTFPF--NEDEDINDQIQNAAFMYPPNPWREISSEAIDLINNLLQVKMRKR 819 Query: 359 LTAAEILNHPWIRE 400 + + L+HPW+++ Sbjct: 820 YSVDKSLSHPWLQD 833
>STK6_RAT (P59241) Serine/threonine-protein kinase 6 (EC 2.7.11.1) (Aurora-A)| (ratAurA) Length = 397 Score = 82.8 bits (203), Expect = 7e-16 Identities = 48/139 (34%), Positives = 74/139 (53%), Gaps = 1/139 (0%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLK-RRYGAEADIWSA 178 EN L + E LK DFG SV P + L G+ Y PE+++ R + + D+WS Sbjct: 253 ENLLLGSNGE---LKIADFGWSVH-APSSRRTTLCGTLDYQPPEMIEGRMHDEKVDLWSL 308 Query: 179 GVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKER 358 GV+ Y L G+PPF A + + + + F ++ GA+DL+ R+L+ + +R Sbjct: 309 GVLCYEFLVGMPPFEAHTYQETYRRISRVEFTFPD----FVTEGARDLISRLLKHNSSQR 364 Query: 359 LTAAEILNHPWIREDGEAP 415 LT AE+L HPWI+ + P Sbjct: 365 LTLAEVLEHPWIKANSSKP 383
>KPCD3_HUMAN (O94806) Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein| kinase C nu type) (nPKC-nu) (Protein kinase EPK2) Length = 890 Score = 82.8 bits (203), Expect = 7e-16 Identities = 45/134 (33%), Positives = 71/134 (52%), Gaps = 1/134 (0%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRR-YGAEADIWSA 178 EN L + +K DFG + R +VG+ Y+APEVL+ + Y D+WS Sbjct: 703 ENVLLASAEPFPQVKLCDFGFARIIGEKSFRRSVVGTPAYLAPEVLRSKGYNRSLDMWSV 762 Query: 179 GVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKER 358 GVI+Y+ LSG PF +E I D + + +PW IS A DL+ +L+ ++R Sbjct: 763 GVIIYVSLSGTFPF--NEDEDINDQIQNAAFMYPPNPWREISGEAIDLINNLLQVKMRKR 820 Query: 359 LTAAEILNHPWIRE 400 + + L+HPW+++ Sbjct: 821 YSVDKSLSHPWLQD 834
>ATG1_CANGA (Q6FL58) Serine/threonine-protein kinase ATG1 (EC 2.7.11.1)| (Autophagy-related protein 1) Length = 942 Score = 82.8 bits (203), Expect = 7e-16 Identities = 42/122 (34%), Positives = 66/122 (54%), Gaps = 1/122 (0%) Frame = +2 Query: 41 LKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLK-RRYGAEADIWSAGVILYILLSGVPP 217 LK DFG + F L GS Y+APE+L ++Y A+AD+WS G +L+ + GVPP Sbjct: 194 LKIADFGFARFLPSTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLFEMCCGVPP 253 Query: 218 FWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHPWIR 397 F A N +F + + H + + + +G K+L+ +L DP +R+ E N+ + Sbjct: 254 FTASNHLELFKKIKRAHDEINFPEVCEVEDGLKELICSLLTFDPAKRIGFEEFFNNKIVT 313 Query: 398 ED 403 ED Sbjct: 314 ED 315
>AAPK1_RAT (P54645) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMPK alpha-1 chain) Length = 548 Score = 82.4 bits (202), Expect = 9e-16 Identities = 62/165 (37%), Positives = 80/165 (48%), Gaps = 2/165 (1%) Frame = +2 Query: 44 KATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRRY--GAEADIWSAGVILYILLSGVPP 217 K DFGLS GE R GS Y APEV+ R G E DIWS+GVILY LL G P Sbjct: 154 KIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLP 213 Query: 218 FWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHPWIR 397 F ++ +F + G PS+ + L+K ML+ DP +R T +I H W + Sbjct: 214 FDDDHVPTLFKKICDGIFYTPQYLNPSVIS----LLKHMLQVDPMKRATIKDIREHEWFK 269 Query: 398 EDGEAPDKPLDITVISRMKQFRAMNKLKKVALKIVAESLSEEEIV 532 +D P D + S M A LK+V K SEEE++ Sbjct: 270 QDLPKYLFPEDPSYSSTMIDDEA---LKEVCEKF---ECSEEEVL 308
>MYLK2_RAT (P20689) Myosin light chain kinase 2, skeletal/cardiac muscle (EC| 2.7.11.18) (MLCK2) Length = 609 Score = 82.4 bits (202), Expect = 9e-16 Identities = 44/137 (32%), Positives = 77/137 (56%), Gaps = 1/137 (0%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKR-RYGAEADIWSA 178 EN L +N +K DFGL+ + P E+ + G+ +++PEV+ + + D+WS Sbjct: 423 ENILCVNTTGHL-VKIIDFGLARRYNPNEKLKVNFGTPEFLSPEVVNYDQISDKTDMWSL 481 Query: 179 GVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKER 358 GVI Y+LLSG+ PF +++ + VL + F + + ++S+ AKD V ++ +D R Sbjct: 482 GVITYMLLSGLSPFLGDDDTETLNNVLSANWYFDEETFEAVSDEAKDFVSNLITKDQSAR 541 Query: 359 LTAAEILNHPWIREDGE 409 ++A + L HPW+ E Sbjct: 542 MSAEQCLAHPWLNNLAE 558
>KIN1_YEAST (P13185) Protein kinase KIN1 (EC 2.7.11.1)| Length = 1064 Score = 82.4 bits (202), Expect = 9e-16 Identities = 49/173 (28%), Positives = 84/173 (48%), Gaps = 14/173 (8%) Frame = +2 Query: 29 EDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRR--YGAEADIWSAGVILYILL 202 + S +K DFGLS + +Q GS Y+ APE+LK G E D+WS GV+L++L+ Sbjct: 279 DSSEIKIIDFGLSNIYDSRKQLHTFCGSLYFAAPELLKANPYTGPEVDVWSFGVVLFVLV 338 Query: 203 SGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILN 382 G PF EN + + + +G +++ +S L+ +ML DPK R T +++ Sbjct: 339 CGKVPFDDENSSVLHEKIKQGKVEYPQ----HLSIEVISLLSKMLVVDPKRRATLKQVVE 394 Query: 383 HPWIREDGEAPD------------KPLDITVISRMKQFRAMNKLKKVALKIVA 505 H W+ P + LDI V+ M + ++ +++ +V+ Sbjct: 395 HHWMVRGFNGPPPSYLPKRVPLTIEMLDINVLKEMYRLEFIDDVEETRSVLVS 447
>AAPK1_PONPY (Q5RDH5) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMPK alpha-1 chain) Length = 550 Score = 82.4 bits (202), Expect = 9e-16 Identities = 62/165 (37%), Positives = 80/165 (48%), Gaps = 2/165 (1%) Frame = +2 Query: 44 KATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRRY--GAEADIWSAGVILYILLSGVPP 217 K DFGLS GE R GS Y APEV+ R G E DIWS+GVILY LL G P Sbjct: 156 KIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLP 215 Query: 218 FWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHPWIR 397 F ++ +F + G PS+ + L+K ML+ DP +R T +I H W + Sbjct: 216 FDDDHVPTLFKKICDGIFYTPQYLNPSVIS----LLKHMLQVDPMKRATIKDIREHEWFK 271 Query: 398 EDGEAPDKPLDITVISRMKQFRAMNKLKKVALKIVAESLSEEEIV 532 +D P D + S M A LK+V K SEEE++ Sbjct: 272 QDLPKYLFPEDPSYSSTMIDDEA---LKEVCEKF---ECSEEEVL 310
>AAPK1_HUMAN (Q13131) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMPK alpha-1 chain) Length = 550 Score = 82.4 bits (202), Expect = 9e-16 Identities = 62/165 (37%), Positives = 80/165 (48%), Gaps = 2/165 (1%) Frame = +2 Query: 44 KATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRRY--GAEADIWSAGVILYILLSGVPP 217 K DFGLS GE R GS Y APEV+ R G E DIWS+GVILY LL G P Sbjct: 156 KIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLP 215 Query: 218 FWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHPWIR 397 F ++ +F + G PS+ + L+K ML+ DP +R T +I H W + Sbjct: 216 FDDDHVPTLFKKICDGIFYTPQYLNPSVIS----LLKHMLQVDPMKRATIKDIREHEWFK 271 Query: 398 EDGEAPDKPLDITVISRMKQFRAMNKLKKVALKIVAESLSEEEIV 532 +D P D + S M A LK+V K SEEE++ Sbjct: 272 QDLPKYLFPEDPSYSSTMIDDEA---LKEVCEKF---ECSEEEVL 310
>KKK1_YEAST (P34244) Probable serine/threonine-protein kinase YKL101W (EC| 2.7.11.1) Length = 1518 Score = 82.4 bits (202), Expect = 9e-16 Identities = 45/137 (32%), Positives = 80/137 (58%), Gaps = 2/137 (1%) Frame = +2 Query: 11 LFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRR--YGAEADIWSAGV 184 L L+K+ + +K DFG++ P + + GS +Y +PE++ R +G +D+WS G+ Sbjct: 245 LLLDKK-NRRIKIADFGMAALELPNKLLKTSCGSPHYASPEIVMGRPYHGGPSDVWSCGI 303 Query: 185 ILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLT 364 +L+ LL+G PF +N + + V G S+ +S+ A+DL+ ++L DP++R+T Sbjct: 304 VLFALLTGHLPFNDDNIKKLLLKVQSGKYQMPSN----LSSEARDLISKILVIDPEKRIT 359 Query: 365 AAEILNHPWIREDGEAP 415 EIL HP I++ + P Sbjct: 360 TQEILKHPLIKKYDDLP 376
>AURKC_HUMAN (Q9UQB9) Serine/threonine-protein kinase 13 (EC 2.7.11.1)| (Aurora/Ipl1/Eg2 protein 2) (Aurora/Ipl1-related kinase 3) (Aurora-C) Length = 309 Score = 81.6 bits (200), Expect = 2e-15 Identities = 45/120 (37%), Positives = 69/120 (57%), Gaps = 1/120 (0%) Frame = +2 Query: 41 LKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLK-RRYGAEADIWSAGVILYILLSGVPP 217 +K DFG SV P + + + G+ Y+ PE+++ R Y + D+W GV+ Y LL G PP Sbjct: 180 VKIADFGWSVH-TPSLRRKTMCGTLDYLPPEMIEGRTYDEKVDLWCIGVLCYELLVGYPP 238 Query: 218 FWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHPWIR 397 F + + + +LK + F S+ GA+DL+ R+LR P ERL A+IL HPW++ Sbjct: 239 FESASHSETYRRILKVDVRFPL----SMPLGARDLISRLLRYQPLERLPLAQILKHPWVQ 294
>STK6L_XENLA (Q91819) Serine/threonine-protein kinase Eg2-like (EC 2.7.11.1)| (p46XlEg22) Length = 408 Score = 81.6 bits (200), Expect = 2e-15 Identities = 49/141 (34%), Positives = 76/141 (53%), Gaps = 1/141 (0%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLK-RRYGAEADIWSA 178 EN L + E LK DFG SV P + L G+ Y+ PE+++ R + + D+WS Sbjct: 267 ENLLLGSNGE---LKIADFGWSVH-APSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSL 322 Query: 179 GVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKER 358 GV+ Y L G PPF + + + + K ++F P+ +S AKDLV ++L+ +P R Sbjct: 323 GVLCYEFLVGKPPFETDTHQETYRRISK--VEFQYPPY--VSEEAKDLVSKLLKHNPNHR 378 Query: 359 LTAAEILNHPWIREDGEAPDK 421 L +L HPWI ++ + P K Sbjct: 379 LPLKGVLEHPWIVKNSQQPKK 399
>AURKC_MOUSE (O88445) Serine/threonine-protein kinase 13 (EC 2.7.11.1)| (Aurora/Ipl1/Eg2 protein 1) (Aurora-C) Length = 282 Score = 81.3 bits (199), Expect = 2e-15 Identities = 43/121 (35%), Positives = 69/121 (57%), Gaps = 1/121 (0%) Frame = +2 Query: 41 LKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRR-YGAEADIWSAGVILYILLSGVPP 217 +K +DFG SV P + + + G+ Y+ PE++ ++ Y D+W GV+ Y LL G PP Sbjct: 153 VKISDFGWSVH-TPSLRRKTMCGTLDYLPPEMIAQKPYNEMVDLWCIGVLCYELLVGKPP 211 Query: 218 FWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHPWIR 397 F + + + + F S S+ GA+DL+ ++LR P ERL+ A++L HPW+R Sbjct: 212 FESSTSSETYRRIRQVDFKFPS----SVPAGAQDLISKLLRYHPSERLSLAQVLKHPWVR 267 Query: 398 E 400 E Sbjct: 268 E 268
>SRK1_SCHPO (O94547) Serine/threonine-protein kinase srk1 (EC 2.7.11.1)| (Sty1-regulated kinase 1) Length = 580 Score = 81.3 bits (199), Expect = 2e-15 Identities = 43/119 (36%), Positives = 62/119 (52%), Gaps = 1/119 (0%) Frame = +2 Query: 41 LKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLK-RRYGAEADIWSAGVILYILLSGVPP 217 ++ DFGLS + G+ Y APE+++ RY D+W+ G +LY +L G PP Sbjct: 304 IRLADFGLSKVVWDSHT-QTPCGTMGYTAPEIVRDERYSKGVDMWALGCVLYTILCGFPP 362 Query: 218 FWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHPWI 394 F+ E+ + V +G F S W IS AKDL+ +L DP+ R + L HPWI Sbjct: 363 FYDESISLLTKKVSRGEYSFLSPWWDDISKSAKDLISHLLTVDPESRYDIHQFLAHPWI 421
>AURKB_HUMAN (Q96GD4) Serine/threonine-protein kinase 12 (EC 2.7.11.1) (Aurora-| and Ipl1-like midbody-associated protein 1) (AIM-1) (Aurora/IPL1-related kinase 2) (Aurora-related kinase 2) (STK-1) (Aurora-B) Length = 344 Score = 81.3 bits (199), Expect = 2e-15 Identities = 47/133 (35%), Positives = 75/133 (56%), Gaps = 1/133 (0%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLK-RRYGAEADIWSA 178 EN L K E LK DFG SV P + + + G+ Y+ PE+++ R + + D+W Sbjct: 204 ENLLLGLKGE---LKIADFGWSVH-APSLRRKTMCGTLDYLPPEMIEGRMHNEKVDLWCI 259 Query: 179 GVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKER 358 GV+ Y LL G PPF + + + ++K + F + S+ GA+DL+ ++LR +P ER Sbjct: 260 GVLCYELLVGNPPFESASHNETYRRIVKVDLKFPA----SVPTGAQDLISKLLRHNPSER 315 Query: 359 LTAAEILNHPWIR 397 L A++ HPW+R Sbjct: 316 LPLAQVSAHPWVR 328
>SN1L1_HUMAN (P57059) Serine/threonine-protein kinase SNF1-like kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase SNF1LK) Length = 783 Score = 81.3 bits (199), Expect = 2e-15 Identities = 47/123 (38%), Positives = 63/123 (51%), Gaps = 2/123 (1%) Frame = +2 Query: 41 LKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVL--KRRYGAEADIWSAGVILYILLSGVP 214 +K DFG F+K GE GS Y APEV K G + DIWS GV+LY+L+ G Sbjct: 163 IKLADFGFGNFYKSGEPLSTWCGSPPYAAPEVFEGKEYEGPQLDIWSLGVVLYVLVCGSL 222 Query: 215 PFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHPWI 394 PF N + VL+G +S + L++RML DP R+T A+I H W+ Sbjct: 223 PFDGPNLPTLRQRVLEGRFRIPF----FMSQDCESLIRRMLVVDPARRITIAQIRQHRWM 278 Query: 395 RED 403 R + Sbjct: 279 RAE 281
>AAPK1_CAEEL (P45894) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMP-activated kinase 1) Length = 589 Score = 80.5 bits (197), Expect = 3e-15 Identities = 46/123 (37%), Positives = 64/123 (52%), Gaps = 2/123 (1%) Frame = +2 Query: 41 LKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRRY--GAEADIWSAGVILYILLSGVP 214 +K DFGLS + G+ GS Y APE++ + G E D+WS GVILY +L G Sbjct: 161 IKIADFGLSNYMTDGDLLSTACGSPNYAAPELISNKLYVGPEVDLWSCGVILYAMLCGTL 220 Query: 215 PFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHPWI 394 PF +N +F + G + P+ S+ A DL+ ML+ DP +R I+NH W Sbjct: 221 PFDDQNVPTLFAKIKSGRY---TVPY-SMEKQAADLISTMLQVDPVKRADVKRIVNHSWF 276 Query: 395 RED 403 R D Sbjct: 277 RID 279
>OBSCN_HUMAN (Q5VST9) Obscurin (Obscurin-myosin light chain kinase)| (Obscurin-MLCK) (Obscurin-RhoGEF) Length = 7968 Score = 80.5 bits (197), Expect = 3e-15 Identities = 46/123 (37%), Positives = 71/123 (57%), Gaps = 1/123 (0%) Frame = +2 Query: 26 REDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRRYGAEA-DIWSAGVILYILL 202 RED +K DFG + P E GS +V+PE++++ +EA DIW+ GVI Y+ L Sbjct: 6600 RED--IKICDFGFAQNITPAELQFSQYGSPEFVSPEIIQQNPVSEASDIWAMGVISYLSL 6657 Query: 203 SGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILN 382 + PF E++ VL+G + +SS +S AKD +K L++ P+ R +AA+ L+ Sbjct: 6658 TCSSPFAGESDRATLLNVLEGRVSWSSPMAAHLSEDAKDFIKATLQRAPQARPSAAQCLS 6717 Query: 383 HPW 391 HPW Sbjct: 6718 HPW 6720 Score = 57.0 bits (136), Expect = 4e-08 Identities = 40/148 (27%), Positives = 73/148 (49%), Gaps = 1/148 (0%) Frame = +2 Query: 80 PGEQFRDLVGSAYYVAPEVLKRRYGA-EADIWSAGVILYILLSGVPPFWAENEEGIFDAV 256 P ++F+D + + +APE+L+ + + DIW+ GV +I+LS P +E + + Sbjct: 7823 PSDKFKDYLET---MAPELLEGQGAVPQTDIWAIGVTAFIMLSAEYPVSSEGARDLQRGL 7879 Query: 257 LKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHPWIREDGEAPDKPLDIT 436 KG + S + +S GA ++ L P R A+ L PW+ E+G A +P +T Sbjct: 7880 RKGLVRLSRC-YAGLSGGAVAFLRSTLCAQPWGRPCASSCLQCPWLTEEGPACSRPAPVT 7938 Query: 437 VISRMKQFRAMNKLKKVALKIVAESLSE 520 + + N+ K+ AL +L++ Sbjct: 7939 FPTARLRVFVRNREKRRALLYKRHNLAQ 7966
>AAPK1_MOUSE (Q5EG47) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMPK alpha-1 chain) Length = 548 Score = 80.5 bits (197), Expect = 3e-15 Identities = 61/165 (36%), Positives = 79/165 (47%), Gaps = 2/165 (1%) Frame = +2 Query: 44 KATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRRY--GAEADIWSAGVILYILLSGVPP 217 K DFGLS GE R GS Y APEV+ R G E DIWS+GVILY LL G P Sbjct: 154 KIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLP 213 Query: 218 FWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHPWIR 397 F ++ +F + G PS+ + L+K ML+ DP +R +I H W + Sbjct: 214 FDDDHVPTLFKKICDGIFYTPQYLNPSVIS----LLKHMLQVDPMKRAAIKDIREHEWFK 269 Query: 398 EDGEAPDKPLDITVISRMKQFRAMNKLKKVALKIVAESLSEEEIV 532 +D P D + S M A LK+V K SEEE++ Sbjct: 270 QDLPKYLFPEDPSYSSTMIDDEA---LKEVCEKF---ECSEEEVL 308
>RCK2_YEAST (P38623) Serine/threonine-protein kinase RCK2 (EC 2.7.11.1) (CAM| kinase-like protein kinase CLK1) Length = 610 Score = 80.5 bits (197), Expect = 3e-15 Identities = 54/191 (28%), Positives = 89/191 (46%), Gaps = 11/191 (5%) Frame = +2 Query: 41 LKATDFGLS--VFFKPGEQFRDLVGSAYYVAPEVLK-RRYGAEADIWSAGVILYILLSGV 211 +K DFGLS +F K + G+ Y APEV+K Y + D+W G +LY +L G Sbjct: 361 VKLADFGLSKQIFSK---NTKTPCGTVGYTAPEVVKDEHYSMKVDMWGIGCVLYTMLCGF 417 Query: 212 PPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHPW 391 PPF+ E + + + + +G F W IS GAK+ V ++L +P +R + L+ PW Sbjct: 418 PPFYDEKIDTLTEKISRGEYTFLKPWWDEISAGAKNAVSKLLELEPSKRYDIDQFLDDPW 477 Query: 392 IR------EDGEAPDKPLDITV--ISRMKQFRAMNKLKKVALKIVAESLSEEEIVGLREM 547 + ++GE+ K + KQF+ + + A ++ + +G Sbjct: 478 LNTFDCLPKEGESSQKKAGTSERRHPHKKQFQLFQRDSSLLFSPAAVAMRDAFDIG--NA 535 Query: 548 FKSLDTDNSGT 580 K + D GT Sbjct: 536 VKRTEEDRMGT 546
>PLK4_HUMAN (O00444) Serine/threonine-protein kinase PLK4 (EC 2.7.11.21)| (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase Sak) (Serine/threonine-protein kinase 18) Length = 970 Score = 80.1 bits (196), Expect = 4e-15 Identities = 45/131 (34%), Positives = 75/131 (57%), Gaps = 2/131 (1%) Frame = +2 Query: 41 LKATDFGLSVFFK-PGEQFRDLVGSAYYVAPEVLKRR-YGAEADIWSAGVILYILLSGVP 214 +K DFGL+ K P E+ L G+ Y++PE+ R +G E+D+WS G + Y LL G P Sbjct: 150 IKIADFGLATQLKMPHEKHYTLCGTPNYISPEIATRSAHGLESDVWSLGCMFYTLLIGRP 209 Query: 215 PFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHPWI 394 PF + + + V+ D+ + SI AKDL+ ++LR++P +RL+ + +L+HP++ Sbjct: 210 PFDTDTVKNTLNKVVLA--DYEMPTFLSIE--AKDLIHQLLRRNPADRLSLSSVLDHPFM 265 Query: 395 REDGEAPDKPL 427 + K L Sbjct: 266 SRNSSTKSKDL 276
>KS6A4_MOUSE (Q9Z2B9) Ribosomal protein S6 kinase alpha-4 (EC 2.7.11.1) (Nuclear| mitogen-and stress-activated protein kinase 2) (90 kDa ribosomal protein S6 kinase 4) (RSK-like protein kinase) (RLSK) Length = 773 Score = 80.1 bits (196), Expect = 4e-15 Identities = 48/151 (31%), Positives = 75/151 (49%), Gaps = 10/151 (6%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFF--KPGEQFRDLVGSAYYVAPEVLKRR-YGAEADIW 172 EN L+ + +P+K DFG + P E + + Y APE+L ++ Y D+W Sbjct: 534 ENILYADDTPGAPVKIIDFGFARLRPQSPAEPMQTPCFTLQYAAPELLAQQGYDESCDLW 593 Query: 173 SAGVILYILLSGVPPFWAENEEG-------IFDAVLKGHIDFSSDPWPSISNGAKDLVKR 331 S GVILY++LSG PF + +G I + +G + W +S AK+LV+ Sbjct: 594 SLGVILYMMLSGQVPFQGASGQGGQSQAAEIMCKIREGRFSLDGEAWQGVSEEAKELVRG 653 Query: 332 MLRQDPKERLTAAEILNHPWIREDGEAPDKP 424 +L DP +RL + + W+ +DG A P Sbjct: 654 LLTVDPAKRLKLEGLRSSSWL-QDGSARSSP 683 Score = 69.3 bits (168), Expect = 8e-12 Identities = 47/126 (37%), Positives = 71/126 (56%), Gaps = 10/126 (7%) Frame = +2 Query: 50 TDFGLSVFFKPGEQFR--DLVGSAYYVAPEVLKRR--YGAEADIWSAGVILYILLSGVPP 217 TDFGLS F E+ R G+ Y+APE+++ + +G D WS G++L+ LL+G P Sbjct: 178 TDFGLSKEFLTEEKERTFSFCGTIEYMAPEIIRSKAGHGKAVDWWSLGILLFELLTGASP 237 Query: 218 FWAENEEGIFDAVLKGHIDFSSDPWP-SISNGAKDLVKRMLRQDPKERLTAA-----EIL 379 F E E A + I S P+P I A+DL++R+L +DPK+RL A E+ Sbjct: 238 FTLEGERNT-QAEVSRRILKCSPPFPLRIGPVAQDLLQRLLCKDPKKRLGAGPQGAQEVK 296 Query: 380 NHPWIR 397 +HP+ + Sbjct: 297 SHPFFQ 302
>CPK11_ARATH (O22932) CBL-interacting serine/threonine-protein kinase 11 (EC| 2.7.11.1) (SOS2-like protein kinase PKS5) (SOS-interacting protein 4) (SNF1-related kinase 3.22) Length = 435 Score = 80.1 bits (196), Expect = 4e-15 Identities = 47/131 (35%), Positives = 70/131 (53%), Gaps = 5/131 (3%) Frame = +2 Query: 29 EDSPLKATDFGLSVF---FKPGEQFRDLVGSAYYVAPEVLKRR--YGAEADIWSAGVILY 193 E+ LK +DFGLS +P L G+ YVAPE+L ++ GA+ D+WS G++L+ Sbjct: 155 ENGNLKVSDFGLSALTDQIRPDGLLHTLCGTPAYVAPEILSKKGYEGAKVDVWSCGIVLF 214 Query: 194 ILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAE 373 +L++G PF N ++ + KG F W +S K V R+L +P+ R+T E Sbjct: 215 VLVAGYLPFNDPNVMNMYKKIYKGEYRFPR--W--MSPDLKRFVSRLLDINPETRITIDE 270 Query: 374 ILNHPWIREDG 406 IL PW G Sbjct: 271 ILKDPWFVRGG 281
>MAPK2_RABIT (P49139) MAP kinase-activated protein kinase 2 (EC 2.7.11.1)| (MAPK-activated protein kinase 2) (MAPKAP kinase 2) (MAPKAPK-2) (MK2) (Fragments) Length = 330 Score = 80.1 bits (196), Expect = 4e-15 Identities = 47/147 (31%), Positives = 66/147 (44%), Gaps = 5/147 (3%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVL-KRRYGAEADIWSA 178 EN L+ +KR + LK TDFG + + YYVAPEVL +Y D+WS Sbjct: 156 ENLLYTSKRPKAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSL 215 Query: 179 GVILYILLSGVPPFWAEN----EEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQD 346 GVI+YILL G PPF++ + G+ + G +F + Sbjct: 216 GVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEXXXXXXXXXXXXXXXXXXX 275 Query: 347 PKERLTAAEILNHPWIREDGEAPDKPL 427 +T E +NHPWI + + P PL Sbjct: 276 XXXXMTITEFMNHPWIMQSTKVPQTPL 302
>SN1L2_CHICK (Q9IA88) Serine/threonine-protein kinase SNF1-like kinase 2 (EC| 2.7.11.1) (Qin-induced kinase) Length = 798 Score = 80.1 bits (196), Expect = 4e-15 Identities = 47/123 (38%), Positives = 65/123 (52%), Gaps = 2/123 (1%) Frame = +2 Query: 41 LKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVL--KRRYGAEADIWSAGVILYILLSGVP 214 +K DFG F+K GE GS Y APEV K G DIWS GV+LY+L+ G Sbjct: 162 IKLADFGFGNFYKSGEPLSTWCGSPPYAAPEVFEGKEYEGPHLDIWSLGVVLYVLVCGSL 221 Query: 215 PFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHPWI 394 PF N + VL+G P+ +S + L++RML DP +R+T ++I H W+ Sbjct: 222 PFDGPNLPTLRQRVLEGRFRI---PY-FMSEDCETLIRRMLVVDPTKRITISQIKQHKWM 277 Query: 395 RED 403 + D Sbjct: 278 QAD 280
>PLK3_HUMAN (Q9H4B4) Serine/threonine-protein kinase PLK3 (EC 2.7.11.21)| (Polo-like kinase 3) (PLK-3) (Cytokine-inducible serine/threonine-protein kinase) (FGF-inducible kinase) (Proliferation-related kinase) Length = 646 Score = 79.3 bits (194), Expect = 8e-15 Identities = 48/133 (36%), Positives = 76/133 (57%), Gaps = 2/133 (1%) Frame = +2 Query: 29 EDSPLKATDFGLSVFFKPGEQFRDLV-GSAYYVAPEVLKRR-YGAEADIWSAGVILYILL 202 E+ LK DFGL+ +P EQ + + G+ YVAPEVL R+ +G EAD+WS G ++Y LL Sbjct: 195 ENMELKVGDFGLAARLEPPEQRKKTICGTPNYVAPEVLLRQGHGPEADVWSLGCVMYTLL 254 Query: 203 SGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILN 382 G PPF + + + + + H + S+S A+ L+ +LR P++R + +IL Sbjct: 255 CGSPPFETADLKETYRCIKQVHYTLPA----SLSLPARQLLAAILRASPRDRPSIDQILR 310 Query: 383 HPWIREDGEAPDK 421 H + + G PD+ Sbjct: 311 HDFFTK-GYTPDR 322
>KS6A4_HUMAN (O75676) Ribosomal protein S6 kinase alpha-4 (EC 2.7.11.1) (Nuclear| mitogen-and stress-activated protein kinase 2) (90 kDa ribosomal protein S6 kinase 4) (Ribosomal protein kinase B) (RSKB) Length = 772 Score = 79.3 bits (194), Expect = 8e-15 Identities = 48/151 (31%), Positives = 74/151 (49%), Gaps = 10/151 (6%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFF--KPGEQFRDLVGSAYYVAPEVLKRR-YGAEADIW 172 EN L+ + +P+K DFG + PG + + Y APE+L ++ Y D+W Sbjct: 534 ENILYADDTPGAPVKIIDFGFARLRPQSPGVPMQTPCFTLQYAAPELLAQQGYDESCDLW 593 Query: 173 SAGVILYILLSGVPPFWAENEEG-------IFDAVLKGHIDFSSDPWPSISNGAKDLVKR 331 S GVILY++LSG PF + +G I + +G + W +S AK+LV+ Sbjct: 594 SLGVILYMMLSGQVPFQGASGQGGQSQAAEIMCKIREGRFSLDGEAWQGVSEEAKELVRG 653 Query: 332 MLRQDPKERLTAAEILNHPWIREDGEAPDKP 424 +L DP +RL + W+ +DG A P Sbjct: 654 LLTVDPAKRLKLEGLRGSSWL-QDGSARSSP 683 Score = 72.0 bits (175), Expect = 1e-12 Identities = 46/125 (36%), Positives = 69/125 (55%), Gaps = 9/125 (7%) Frame = +2 Query: 50 TDFGLSVFFKPGEQFR--DLVGSAYYVAPEVLKRR--YGAEADIWSAGVILYILLSGVPP 217 TDFGLS F E+ R G+ Y+APE+++ + +G D WS G++L+ LL+G P Sbjct: 178 TDFGLSKEFLTEEKERTFSFCGTIEYMAPEIIRSKTGHGKAVDWWSLGILLFELLTGASP 237 Query: 218 FWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAA-----EILN 382 F E E V + + S P I A+DL++R+L +DPK+RL A E+ N Sbjct: 238 FTLEGERNTQAEVSRRILKCSPPFPPRIGPVAQDLLQRLLCKDPKKRLGAGPQGAQEVRN 297 Query: 383 HPWIR 397 HP+ + Sbjct: 298 HPFFQ 302
>IPL1_YEAST (P38991) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) (Increase-in-ploidy protein 1) Length = 367 Score = 79.3 bits (194), Expect = 8e-15 Identities = 40/119 (33%), Positives = 69/119 (57%), Gaps = 1/119 (0%) Frame = +2 Query: 41 LKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLK-RRYGAEADIWSAGVILYILLSGVPP 217 +K TDFG S+ P + + + G+ Y++PE+++ R Y D W+ GV+ + LL+G PP Sbjct: 241 IKLTDFGWSIINPPENRRKTVCGTIDYLSPEMVESREYDHTIDAWALGVLAFELLTGAPP 300 Query: 218 FWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHPWI 394 F E ++ + + I S+ IS A+DL+ ++L+ DPK+R+ ++ HPWI Sbjct: 301 FEEEMKDTTYKRIAALDIKMPSN----ISQDAQDLILKLLKYDPKDRMRLGDVKMHPWI 355
>ATG1_BOTCI (Q6H9I1) Serine/threonine-protein kinase ATG1 (EC 2.7.11.1)| (Autophagy-related protein 1) (Botryotinia fuckeliana putative kinase exons 1-3) Length = 952 Score = 79.3 bits (194), Expect = 8e-15 Identities = 42/121 (34%), Positives = 64/121 (52%), Gaps = 1/121 (0%) Frame = +2 Query: 41 LKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLK-RRYGAEADIWSAGVILYILLSGVPP 217 LK DFG + L GS Y+APE+L+ +Y A AD+WS G +LY +++G PP Sbjct: 211 LKLADFGFARSLPSTSLAETLCGSPLYMAPEILRYEKYDARADLWSIGTVLYEMMTGRPP 270 Query: 218 FWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHPWIR 397 F A N + + K + S KD+V+R+L++ P++R+T E HP + Sbjct: 271 FKAINHVQLLQKIEKNQDEIRFPSRGIYSRDLKDIVRRLLKKKPEDRITFPEYFAHPVVT 330 Query: 398 E 400 E Sbjct: 331 E 331
>SN1L2_HUMAN (Q9H0K1) Serine/threonine-protein kinase SNF1-like kinase 2 (EC| 2.7.11.1) (Qin-induced kinase) Length = 926 Score = 79.3 bits (194), Expect = 8e-15 Identities = 51/133 (38%), Positives = 68/133 (51%), Gaps = 2/133 (1%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRRY--GAEADIWS 175 EN L N +K DFG FFK GE GS Y APEV + + G + DIWS Sbjct: 146 ENLLLDNNMN---IKIADFGFGNFFKSGELLATWCGSPPYAAPEVFEGQQYEGPQLDIWS 202 Query: 176 AGVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKE 355 GV+LY+L+ G PF + VL+G P+ +S + L++RML DP + Sbjct: 203 MGVVLYVLVCGALPFDGPTLPILRQRVLEGRFRI---PY-FMSEDCEHLIRRMLVLDPSK 258 Query: 356 RLTAAEILNHPWI 394 RLT A+I H W+ Sbjct: 259 RLTIAQIKEHKWM 271
>UNC89_CAEEL (O01761) Muscle M-line assembly protein unc-89 (Uncoordinated protein| 89) Length = 8081 Score = 79.0 bits (193), Expect = 1e-14 Identities = 48/143 (33%), Positives = 72/143 (50%), Gaps = 1/143 (0%) Frame = +2 Query: 29 EDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRR-YGAEADIWSAGVILYILLS 205 +D LK DFG + G ++ GS +V+PE+++ D+WS GV+ Y+LL+ Sbjct: 6758 QDDKLKLADFGQARRLLRGLITGEIKGSPEFVSPEIVRSYPLTLATDMWSTGVLTYVLLT 6817 Query: 206 GVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNH 385 G+ PF +N+ V F S P + S A D VK++L + P RLT E L+H Sbjct: 6818 GLSPFHGDNDNETLANV--DSCQFDSSPLGNFSYDAGDFVKKLLTEIPVSRLTVDEALDH 6875 Query: 386 PWIREDGEAPDKPLDITVISRMK 454 PWI D + +PL + K Sbjct: 6876 PWI-NDEKLKTEPLSADTLREFK 6897 Score = 39.3 bits (90), Expect = 0.009 Identities = 40/160 (25%), Positives = 71/160 (44%), Gaps = 5/160 (3%) Frame = +2 Query: 5 NFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPE--VLKRRYGAEADIWSA 178 N +F +KR +K DFG + K + + + +PE + + ++D+W Sbjct: 7906 NIMFQSKRS-WVVKLVDFGRAQ--KVSGAVKPVDFDTKWASPEFHIPETPVTVQSDMWGM 7962 Query: 179 GVILYILLSGVPPFWAE--NEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPK 352 GV+ + LL+G PF +E EE I + V+ D + P + S L++ P Sbjct: 7963 GVVTFCLLAGFHPFTSEYDREEEIKENVINVKCDPNLIP-VNASQECLSFATWALKKSPV 8021 Query: 353 ERLTAAEILNHPWIREDGEAPDKPLDITV-ISRMKQFRAM 469 R+ E L+H ++ D + I SR+++ AM Sbjct: 8022 RRMRTDEALSHKFLSSDPSMVRRRESIKYSASRLRKLAAM 8061
>PLK3_MOUSE (Q60806) Serine/threonine-protein kinase PLK3 (EC 2.7.11.21)| (Polo-like kinase 3) (PLK-3) (Cytokine-inducible serine/threonine-protein kinase) (FGF-inducible kinase) Length = 631 Score = 79.0 bits (193), Expect = 1e-14 Identities = 50/141 (35%), Positives = 78/141 (55%), Gaps = 2/141 (1%) Frame = +2 Query: 5 NFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLV-GSAYYVAPEVLKRR-YGAEADIWSA 178 NF + E LK DFGL+ +P EQ + + G+ YVAPEVL R+ +G EAD+WS Sbjct: 191 NFFITDNME---LKVGDFGLAARLEPPEQRKKTICGTPNYVAPEVLLRQGHGPEADVWSL 247 Query: 179 GVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKER 358 G ++Y LL G PPF + + + + + H + S+S A+ L+ +LR P++R Sbjct: 248 GCVMYTLLCGSPPFETADLKETYRCIKQVHYTLPA----SLSLPARQLLAAILRASPRDR 303 Query: 359 LTAAEILNHPWIREDGEAPDK 421 + +IL H + + G PD+ Sbjct: 304 PSIEQILRHDFFTK-GYTPDR 323
>PLK3_RAT (Q9R011) Serine/threonine-protein kinase PLK3 (EC 2.7.11.21)| (Polo-like kinase 3) (PLK-3) (Cytokine-inducible serine/threonine-protein kinase) (FGF-inducible kinase) (Fragment) Length = 615 Score = 79.0 bits (193), Expect = 1e-14 Identities = 50/141 (35%), Positives = 78/141 (55%), Gaps = 2/141 (1%) Frame = +2 Query: 5 NFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLV-GSAYYVAPEVLKRR-YGAEADIWSA 178 NF + E LK DFGL+ +P EQ + + G+ YVAPEVL R+ +G EAD+WS Sbjct: 159 NFFITDNME---LKVGDFGLAARLEPPEQRKKTICGTPNYVAPEVLLRQGHGPEADVWSL 215 Query: 179 GVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKER 358 G ++Y LL G PPF + + + + + H + S+S A+ L+ +LR P++R Sbjct: 216 GCVMYTLLCGSPPFETADLKETYRCIKQVHYTLPA----SLSLPARQLLAAILRASPRDR 271 Query: 359 LTAAEILNHPWIREDGEAPDK 421 + +IL H + + G PD+ Sbjct: 272 PSIEQILRHDFFTK-GYTPDR 291
>SNF1_CANTR (O94168) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 619 Score = 78.6 bits (192), Expect = 1e-14 Identities = 50/140 (35%), Positives = 70/140 (50%), Gaps = 2/140 (1%) Frame = +2 Query: 41 LKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRRY--GAEADIWSAGVILYILLSGVP 214 +K DFGLS G + GS Y APEV+ + G E D+WS+GVILY++L G Sbjct: 188 VKIADFGLSNIMTDGNFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSSGVILYVMLCGRL 247 Query: 215 PFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHPWI 394 PF E +F + G + +S GAK L+ RML +P R+T EI+ W Sbjct: 248 PFDDEFIPALFKKISNGVYTLPN----YLSPGAKHLLTRMLVVNPLNRITIHEIMEDEWF 303 Query: 395 REDGEAPDKPLDITVISRMK 454 ++D P D++ I K Sbjct: 304 KQDMPDYLLPPDLSKIKTSK 323
>PAK6_HUMAN (Q9NQU5) Serine/threonine-protein kinase PAK 6 (EC 2.7.11.1)| (p21-activated kinase 6) (PAK-6) (PAK-5) Length = 681 Score = 78.2 bits (191), Expect = 2e-14 Identities = 45/133 (33%), Positives = 74/133 (55%), Gaps = 8/133 (6%) Frame = +2 Query: 32 DSPLKATDFGLSV-FFKPGEQFRDLVGSAYYVAPEVLKRR-YGAEADIWSAGVILYILLS 205 D +K +DFG K + + LVG+ Y++APEV+ R Y E DIWS G+++ ++ Sbjct: 537 DGRVKLSDFGFCAQISKDVPKRKSLVGTPYWMAPEVISRSLYATEVDIWSLGIMVIEMVD 596 Query: 206 GVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAK------DLVKRMLRQDPKERLTA 367 G PP+++ D+ ++ P P + N K D ++RML +DP+ER TA Sbjct: 597 GEPPYFS-------DSPVQAMKRLRDSPPPKLKNSHKVSPVLRDFLERMLVRDPQERATA 649 Query: 368 AEILNHPWIREDG 406 E+L+HP++ + G Sbjct: 650 QELLDHPFLLQTG 662
>IPL1_DEBHA (Q6BVA0) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 412 Score = 78.2 bits (191), Expect = 2e-14 Identities = 43/124 (34%), Positives = 70/124 (56%), Gaps = 3/124 (2%) Frame = +2 Query: 32 DSPLKATDFGLSVFFKPGEQFRDLV--GSAYYVAPEVLK-RRYGAEADIWSAGVILYILL 202 D+ +K +DFG SV P + L G+ Y+ PE+++ + DIWS G++ Y L Sbjct: 282 DNCIKLSDFGWSVKSLPSSSTKRLTICGTLDYLPPEMIESNEHDYTVDIWSLGILCYEFL 341 Query: 203 SGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILN 382 G PPF ++ + + K + S +S+ A DL+ R+L++ PK+R+T AE++N Sbjct: 342 VGKPPFEEIDKNSTYKRIAKVDLKIPS----FLSSEATDLILRLLQKSPKKRITLAEVMN 397 Query: 383 HPWI 394 HPWI Sbjct: 398 HPWI 401
>AURKB_MOUSE (O70126) Serine/threonine-protein kinase 12 (EC 2.7.11.1)| (Aurora-related kinase 2) (Serine/threonine-protein kinase 5) (STK-1) (Aurora-B) Length = 345 Score = 78.2 bits (191), Expect = 2e-14 Identities = 42/120 (35%), Positives = 70/120 (58%), Gaps = 1/120 (0%) Frame = +2 Query: 41 LKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRRYGAE-ADIWSAGVILYILLSGVPP 217 LK DFG SV P + + + G+ Y+ PE+++ R E D+W GV+ Y L+ G PP Sbjct: 219 LKIADFGWSVH-APSLRRKTMCGTLDYLPPEMIEGRMHNEMVDLWCIGVLCYELMVGNPP 277 Query: 218 FWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHPWIR 397 F + + + ++K + F S S+ +GA+DL+ ++L+ +P +RL AE+ HPW+R Sbjct: 278 FESPSHSETYRRIVKVDLKFPS----SVPSGAQDLISKLLKHNPWQRLPLAEVAAHPWVR 333
>AAPK2_PONPY (Q5RD00) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMPK alpha-2 chain) Length = 552 Score = 77.8 bits (190), Expect = 2e-14 Identities = 47/122 (38%), Positives = 63/122 (51%), Gaps = 2/122 (1%) Frame = +2 Query: 44 KATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRRY--GAEADIWSAGVILYILLSGVPP 217 K DFGLS GE R GS Y APEV+ R G E DIWS GVILY LL G P Sbjct: 154 KIADFGLSNIMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSCGVILYALLCGTLP 213 Query: 218 FWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHPWIR 397 F E+ +F + +G + + + ++ L+ ML+ DP +R T +I H W + Sbjct: 214 FDDEHVPTLFKKI-RGGVFYIPE---YLNRSVATLLMHMLQVDPLKRATIKDIREHEWFK 269 Query: 398 ED 403 +D Sbjct: 270 QD 271
>AAPK2_PIG (Q28948) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMPK alpha-2 chain) Length = 552 Score = 77.8 bits (190), Expect = 2e-14 Identities = 47/122 (38%), Positives = 63/122 (51%), Gaps = 2/122 (1%) Frame = +2 Query: 44 KATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRRY--GAEADIWSAGVILYILLSGVPP 217 K DFGLS GE R GS Y APEV+ R G E DIWS GVILY LL G P Sbjct: 154 KIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSCGVILYALLCGTLP 213 Query: 218 FWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHPWIR 397 F E+ +F + +G + + + ++ L+ ML+ DP +R T +I H W + Sbjct: 214 FDDEHVPTLFKKI-RGGVFYIPE---YLNRSVATLLMHMLQVDPLKRATIKDIREHEWFK 269 Query: 398 ED 403 +D Sbjct: 270 QD 271
>AAPK2_HUMAN (P54646) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMPK alpha-2 chain) Length = 552 Score = 77.8 bits (190), Expect = 2e-14 Identities = 47/122 (38%), Positives = 63/122 (51%), Gaps = 2/122 (1%) Frame = +2 Query: 44 KATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRRY--GAEADIWSAGVILYILLSGVPP 217 K DFGLS GE R GS Y APEV+ R G E DIWS GVILY LL G P Sbjct: 154 KIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSCGVILYALLCGTLP 213 Query: 218 FWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHPWIR 397 F E+ +F + +G + + + ++ L+ ML+ DP +R T +I H W + Sbjct: 214 FDDEHVPTLFKKI-RGGVFYIPE---YLNRSVATLLMHMLQVDPLKRATIKDIREHEWFK 269 Query: 398 ED 403 +D Sbjct: 270 QD 271
>STK6_HUMAN (O14965) Serine/threonine-protein kinase 6 (EC 2.7.11.1)| (Serine/threonine kinase 15) (Aurora/IPL1-related kinase 1) (Aurora-related kinase 1) (hARK1) (Aurora-A) (Breast-tumor-amplified kinase) Length = 403 Score = 77.8 bits (190), Expect = 2e-14 Identities = 42/126 (33%), Positives = 66/126 (52%), Gaps = 1/126 (0%) Frame = +2 Query: 41 LKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLK-RRYGAEADIWSAGVILYILLSGVPP 217 LK DFG SV P + L G+ Y+ PE+++ R + + D+WS GV+ Y L G PP Sbjct: 270 LKIADFGWSVH-APSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPP 328 Query: 218 FWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHPWIR 397 F A + + + + F ++ GA+DL+ R+L+ +P +R E+L HPWI Sbjct: 329 FEANTYQETYKRISRVEFTFPD----FVTEGARDLISRLLKHNPSQRPMLREVLEHPWIT 384 Query: 398 EDGEAP 415 + P Sbjct: 385 ANSSKP 390
>ATG1_CANAL (Q5A649) Serine/threonine-protein kinase ATG1 (EC 2.7.11.1)| (Autophagy-related protein 1) Length = 834 Score = 77.8 bits (190), Expect = 2e-14 Identities = 43/131 (32%), Positives = 66/131 (50%), Gaps = 1/131 (0%) Frame = +2 Query: 41 LKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLK-RRYGAEADIWSAGVILYILLSGVPP 217 LK DFG + F L GS Y+APE+L+ +Y A+AD+WS G +LY + G PP Sbjct: 236 LKIADFGFARFLPSTSMAETLCGSPLYMAPEILRYEKYNAKADLWSVGAVLYEMTVGKPP 295 Query: 218 FWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHPWIR 397 F A N + + K + + K L++ +L+ +P ER++ E N I Sbjct: 296 FKAGNHIELLKNIEKANDKIKFPSAAQVPEPLKQLIRSLLKYNPTERISFNEFFNDSLIT 355 Query: 398 EDGEAPDKPLD 430 D + D+PL+ Sbjct: 356 CDLDDNDQPLE 366
>RKIN1_SECCE (Q02723) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 502 Score = 77.8 bits (190), Expect = 2e-14 Identities = 50/134 (37%), Positives = 66/134 (49%), Gaps = 2/134 (1%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRRY--GAEADIWS 175 EN L +K +K DFGLS G + GS Y APEV+ + G E D+WS Sbjct: 144 ENLLLDSKYN---VKLADFGLSNVMHDGHFLKTSCGSLNYAAPEVISGKLYAGPEIDVWS 200 Query: 176 AGVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKE 355 GVILY LL G PF +N +F + G +S+ +DL+ RML DP + Sbjct: 201 CGVILYALLCGAVPFDDDNIPNLFKKIKGGTYILPI----YLSDLVRDLISRMLIVDPMK 256 Query: 356 RLTAAEILNHPWIR 397 R+T EI H W + Sbjct: 257 RITIGEIRKHSWFQ 270
>CIPK1_ARATH (Q8RWC9) CBL-interacting serine/threonine-protein kinase 1 (EC| 2.7.11.1) (SOS2-like protein kinase PKS13) (SNF1-related kinase 3.16) Length = 444 Score = 77.8 bits (190), Expect = 2e-14 Identities = 50/124 (40%), Positives = 66/124 (53%), Gaps = 5/124 (4%) Frame = +2 Query: 41 LKATDFGLSVF---FKPGEQFRDLVGSAYYVAPEVLKRRY--GAEADIWSAGVILYILLS 205 +K TDFGLS F+ GS YVAPEVL R GA +DIWS GVILY++L+ Sbjct: 157 IKITDFGLSALPQHFRDDGLLHTTCGSPNYVAPEVLANRGYDGAASDIWSCGVILYVILT 216 Query: 206 GVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNH 385 G PF N ++ + KG D W +S GA+ ++KRML +P R+T I Sbjct: 217 GCLPFDDRNLAVLYQKICKG--DPPIPRW--LSPGARTMIKRMLDPNPVTRITVVGIKAS 272 Query: 386 PWIR 397 W + Sbjct: 273 EWFK 276
>SN1L2_MOUSE (Q8CFH6) Serine/threonine-protein kinase SNF1-like kinase 2 (EC| 2.7.11.1) (Salt-inducible kinase 2) Length = 931 Score = 77.8 bits (190), Expect = 2e-14 Identities = 50/133 (37%), Positives = 68/133 (51%), Gaps = 2/133 (1%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRRY--GAEADIWS 175 EN L N +K DFG FFK GE GS Y APEV + + G + DIWS Sbjct: 146 ENLLLDNNMN---IKIADFGFGNFFKTGELLATWCGSPPYAAPEVFEGQQYEGPQLDIWS 202 Query: 176 AGVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKE 355 GV+LY+L+ G PF + VL+G P+ +S + L++RML DP + Sbjct: 203 MGVVLYVLVCGALPFDGPTLPILRQRVLEGRFRI---PY-FMSEDCEHLIRRMLVLDPSK 258 Query: 356 RLTAAEILNHPWI 394 RL+ A+I H W+ Sbjct: 259 RLSIAQIKEHKWM 271
>RAD53_YEAST (P22216) Serine/threonine-protein kinase RAD53 (EC 2.7.11.1)| (Serine-protein kinase 1) Length = 821 Score = 77.4 bits (189), Expect = 3e-14 Identities = 44/139 (31%), Positives = 71/139 (51%), Gaps = 16/139 (11%) Frame = +2 Query: 29 EDSPL--KATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRR--------------YGAE 160 +D P+ K TDFGL+ G + G+ YVAPEV++ + Y + Sbjct: 329 QDDPVLVKITDFGLAKVQGNGSFMKTFCGTLAYVAPEVIRGKDTSVSPDEYEERNEYSSL 388 Query: 161 ADIWSAGVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLR 340 D+WS G ++Y++L+G PF ++ ++ + +G IS A+D + +L+ Sbjct: 389 VDMWSMGCLVYVILTGHLPFSGSTQDQLYKQIGRGSYHEGPLKDFRISEEARDFIDSLLQ 448 Query: 341 QDPKERLTAAEILNHPWIR 397 DP R TAA+ LNHPWI+ Sbjct: 449 VDPNNRSTAAKALNHPWIK 467
>AAPK2_RAT (Q09137) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMPK alpha-2 chain) Length = 552 Score = 77.4 bits (189), Expect = 3e-14 Identities = 47/122 (38%), Positives = 63/122 (51%), Gaps = 2/122 (1%) Frame = +2 Query: 44 KATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRRY--GAEADIWSAGVILYILLSGVPP 217 K DFGLS GE R GS Y APEV+ R G E DIWS GVILY LL G P Sbjct: 154 KIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSCGVILYALLCGTLP 213 Query: 218 FWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHPWIR 397 F E+ +F + +G + + + ++ L+ ML+ DP +R T +I H W + Sbjct: 214 FDDEHVPTLFKKI-RGGVFYIPE---YLNRSIATLLMHMLQVDPLKRATIKDIREHEWFK 269 Query: 398 ED 403 +D Sbjct: 270 QD 271
>ST17B_RAT (Q91XS8) Serine/threonine-protein kinase 17B (EC 2.7.11.1) (DAP| kinase-related apoptosis-inducing protein kinase 2) Length = 371 Score = 77.4 bits (189), Expect = 3e-14 Identities = 37/121 (30%), Positives = 73/121 (60%), Gaps = 1/121 (0%) Frame = +2 Query: 41 LKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRRYGAEA-DIWSAGVILYILLSGVPP 217 +K DFG+S + R+++G+ Y+APE+L A D+W+ G+I Y+LL+ P Sbjct: 175 IKIVDFGMSRKIGNASELREIMGTPEYLAPEILNYDPITTATDMWNIGIIAYMLLTHTSP 234 Query: 218 FWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHPWIR 397 F E+ + + + + ++D+S + + S+S A D ++ +L ++P++R TA L+H W++ Sbjct: 235 FVGEDNQETYLNISQVNVDYSEEMFSSVSQLATDFIQSLLVKNPEKRPTAESCLSHSWLQ 294 Query: 398 E 400 + Sbjct: 295 Q 295
>ST17B_MOUSE (Q8BG48) Serine/threonine-protein kinase 17B (EC 2.7.11.1) (DAP| kinase-related apoptosis-inducing protein kinase 2) Length = 372 Score = 77.4 bits (189), Expect = 3e-14 Identities = 37/121 (30%), Positives = 73/121 (60%), Gaps = 1/121 (0%) Frame = +2 Query: 41 LKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRRYGAEA-DIWSAGVILYILLSGVPP 217 +K DFG+S + R+++G+ Y+APE+L A D+W+ G+I Y+LL+ P Sbjct: 175 IKIVDFGMSRKIGNASELREIMGTPEYLAPEILNYDPITTATDMWNIGIIAYMLLTHTSP 234 Query: 218 FWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHPWIR 397 F E+ + + + + ++D+S + + S+S A D ++ +L ++P++R TA L+H W++ Sbjct: 235 FVGEDNQETYLNISQVNVDYSEEMFSSVSQLATDFIQSLLVKNPEKRPTAESCLSHSWLQ 294 Query: 398 E 400 + Sbjct: 295 Q 295
>CPK24_ARATH (Q9LDI3) CBL-interacting serine/threonine-protein kinase 24 (EC| 2.7.11.1) (SNF1-related kinase 3.11) (SALT OVERLY SENSITIVE 2 protein) Length = 446 Score = 77.4 bits (189), Expect = 3e-14 Identities = 49/122 (40%), Positives = 67/122 (54%), Gaps = 3/122 (2%) Frame = +2 Query: 41 LKATDFGLSVFFKPG-EQFRDLVGSAYYVAPEVLKRRY--GAEADIWSAGVILYILLSGV 211 LK +DFGLS + G E R G+ YVAPEVL + G+ ADIWS GVIL+++L+G Sbjct: 148 LKVSDFGLSALPQEGVELLRTTCGTPNYVAPEVLSGQGYDGSAADIWSCGVILFVILAGY 207 Query: 212 PPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHPW 391 PF + G++ + +FS PW S K L+ R+L +PK R+ I PW Sbjct: 208 LPFSETDLPGLYRKI--NAAEFSCPPW--FSAEVKFLIHRILDPNPKTRIQIQGIKKDPW 263 Query: 392 IR 397 R Sbjct: 264 FR 265
>CDS1_SCHPO (Q09170) Serine/threonine-protein kinase cds1 (EC 2.7.11.1)| (Checkpoint kinase cds1) Length = 460 Score = 77.4 bits (189), Expect = 3e-14 Identities = 48/138 (34%), Positives = 70/138 (50%), Gaps = 8/138 (5%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLS-VFFKPGEQFRDLVGSAYYVAPEVLKRR-------YGA 157 EN L N D LK +DFGL+ V G G+ Y+APEVLK + Y Sbjct: 298 ENILITN---DFHLKISDFGLAKVIHGTGTFLETFCGTMGYLAPEVLKSKNVNLDGGYDD 354 Query: 158 EADIWSAGVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRML 337 + DIWS G +LY++L+ PF + ++ + + KG IS DL+ RML Sbjct: 355 KVDIWSLGCVLYVMLTASIPFASSSQAKCIELISKGAYPIEPLLENEISEEGIDLINRML 414 Query: 338 RQDPKERLTAAEILNHPW 391 +P++R++ +E L HPW Sbjct: 415 EINPEKRISESEALQHPW 432
>ATG1_PICAN (Q8TFN2) Serine/threonine-protein kinase ATG1 (EC 2.7.11.1)| (Autophagy-related protein 1) (Peroxisome degradation deficient protein 7) Length = 804 Score = 77.0 bits (188), Expect = 4e-14 Identities = 42/131 (32%), Positives = 66/131 (50%), Gaps = 1/131 (0%) Frame = +2 Query: 41 LKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLK-RRYGAEADIWSAGVILYILLSGVPP 217 LK DFG + F L GS Y+APE+L+ +Y A+AD+WS G ++Y + G PP Sbjct: 190 LKIADFGFARFLPSTSMAETLCGSPLYMAPEILRYEKYNAKADLWSVGAVIYEMSVGKPP 249 Query: 218 FWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHPWIR 397 F A N + + K + + + + L+ +L+ +P ER+ E N P I Sbjct: 250 FRASNHVELLRKIEKSKDEITFPVSAEVPDDLVRLICGLLKANPTERMGFQEFFNDPLIV 309 Query: 398 EDGEAPDKPLD 430 D + D+PL+ Sbjct: 310 YDVQCADEPLE 320
>STK6_XENLA (Q91820) Serine/threonine-protein kinase Eg2 (EC 2.7.11.1) (pEg2)| (p46Eg265) Length = 407 Score = 77.0 bits (188), Expect = 4e-14 Identities = 50/145 (34%), Positives = 77/145 (53%), Gaps = 3/145 (2%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRRYGAEA-DIWSA 178 EN L + E LK DFG SV P + L G+ Y+ PE+++ R E D+WS Sbjct: 267 ENLLLGSNGE---LKIADFGWSVH-APSSRRTTLCGTLDYLPPEMIEGRMHDETVDLWSL 322 Query: 179 GVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKER 358 GV+ Y L G PPF + + + + K ++F P+ +S A+DLV ++L+ +P R Sbjct: 323 GVLCYEFLVGKPPFETDTHQETYRRISK--VEFQYPPY--VSEEARDLVSKLLKHNPNHR 378 Query: 359 LTAAEILNHPWIREDGE--APDKPL 427 L +L HPWI ++ + D+PL Sbjct: 379 LPLKGVLEHPWIIKNSQLKKKDEPL 403
>AAPK2_CAEEL (Q95ZQ4) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMP-activated kinase 2) Length = 626 Score = 76.6 bits (187), Expect = 5e-14 Identities = 50/157 (31%), Positives = 74/157 (47%), Gaps = 12/157 (7%) Frame = +2 Query: 29 EDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRRY--GAEADIWSAGVILYILL 202 E + +K DFGLS G+ R GS Y APEV+ + G E D+WS GVILY LL Sbjct: 220 EQNNVKIADFGLSNIMTDGDFLRTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYALL 279 Query: 203 SGVPPFWAENEEGIFDAVLKGHIDFSSDPWPS-ISNGAKDLVKRMLRQDPKERLTAAEIL 379 G PF E+ +F + G P P + +L+ ML DP +R T +++ Sbjct: 280 CGTLPFDDEHVPSLFRKIKSGVF-----PTPDFLERPIVNLLHHMLCVDPMKRATIKDVI 334 Query: 380 NHPWIRED---------GEAPDKPLDITVISRMKQFR 463 H W ++D E+ +DI + + +F+ Sbjct: 335 AHEWFQKDLPNYLFPPINESEASIVDIEAVREVTEFQ 371
>SAPK9_ORYSA (Q75V57) Serine/threonine-protein kinase SAPK9 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 9) Length = 361 Score = 76.6 bits (187), Expect = 5e-14 Identities = 52/147 (35%), Positives = 74/147 (50%), Gaps = 18/147 (12%) Frame = +2 Query: 41 LKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVL-KRRY-GAEADIWSAGVILYILLSGVP 214 LK DFG S Q + VG+ Y+APEVL K+ Y G AD+WS GV LY++L G Sbjct: 157 LKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYDGKIADVWSCGVTLYVMLVGAY 216 Query: 215 PFWAENEEGIFDAVLKG--HIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHP 388 PF + F ++ + +S + IS +DL+ R+ +P R+T EI NHP Sbjct: 217 PFEDPEDPKNFRKTIQKILGVQYSIPDYVHISPECRDLITRIFVGNPASRITMPEIKNHP 276 Query: 389 W--------IREDG------EAPDKPL 427 W + +DG E PD+P+ Sbjct: 277 WFMKNIPADLMDDGMVSNQYEEPDQPM 303
>PKH1_YEAST (Q03407) Serine/threonine-protein kinase PKH1 (EC 2.7.11.1)| (3-phosphoinositide-dependent protein kinase 1) Length = 766 Score = 76.6 bits (187), Expect = 5e-14 Identities = 63/185 (34%), Positives = 92/185 (49%), Gaps = 20/185 (10%) Frame = +2 Query: 41 LKATDFGLSVFFKP-------GEQFRDL-------VGSAYYVAPEVLKRRY-GAEADIWS 175 +K TDFG + G+ + DL VG+A YV+PE+L Y + DIW+ Sbjct: 263 VKLTDFGTAKILPEEPSNTADGKPYFDLYAKSKSFVGTAEYVSPELLNDNYTDSRCDIWA 322 Query: 176 AGVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKE 355 G ILY +L+G PPF A NE F V+K F++ +P I KDLVK++L +DP + Sbjct: 323 FGCILYQMLAGKPPFKAANEYLTFQKVMKIQYAFTAG-FPQI---VKDLVKKLLVRDPND 378 Query: 356 RLTAAEILNHPWIR----EDGEA-PDKPLDITVISRMKQFRAMNKLKKVALKIVAESLSE 520 RLT +I H + EDG D P +I + AM L+KV+ ++ Sbjct: 379 RLTIKQIKAHLFFHEVNFEDGSVWDDNPPEIQPYKINAE--AMKPLQKVSESDTTVKMAN 436 Query: 521 EEIVG 535 ++ G Sbjct: 437 LQLAG 441
>CPK15_ARATH (P92937) CBL-interacting serine/threonine-protein kinase 15 (EC| 2.7.11.1) (Serine/threonine-protein kinase ATPK10) (SOS2-like protein kinase PKS3) (SOS-interacting protein 2) (SNF1-related kinase 3.1) Length = 421 Score = 76.3 bits (186), Expect = 6e-14 Identities = 47/129 (36%), Positives = 70/129 (54%), Gaps = 5/129 (3%) Frame = +2 Query: 29 EDSPLKATDFGLSVFFKPGEQ---FRDLVGSAYYVAPEVLKRRY--GAEADIWSAGVILY 193 E LK +DFGLS Q G+ YVAPEV+ R G +AD+WS GVIL+ Sbjct: 144 EHGNLKISDFGLSALSDSRRQDGLLHTTCGTPAYVAPEVISRNGYDGFKADVWSCGVILF 203 Query: 194 ILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAE 373 +LL+G PF N ++ + K + F + W ++ GAK L+KR+L +P R++ + Sbjct: 204 VLLAGYLPFRDSNLMELYKKIGKAEVKFPN--W--LAPGAKRLLKRILDPNPNTRVSTEK 259 Query: 374 ILNHPWIRE 400 I+ W R+ Sbjct: 260 IMKSSWFRK 268
>SAPK6_ORYSA (Q6ZI44) Serine/threonine-protein kinase SAPK6 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 6) Length = 365 Score = 76.3 bits (186), Expect = 6e-14 Identities = 50/160 (31%), Positives = 79/160 (49%), Gaps = 4/160 (2%) Frame = +2 Query: 41 LKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRRY--GAEADIWSAGVILYILLSGVP 214 LK DFG S + + VG+ Y+APEVL RR G AD+WS GV LY++L G Sbjct: 139 LKICDFGYSKSSLLHSKPKSTVGTPAYIAPEVLSRREYDGKMADVWSCGVTLYVMLVGAY 198 Query: 215 PFWAENEEGIFDAVLKG--HIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHP 388 PF ++ F + I + + IS + L+ R+ +P +R+T EI NHP Sbjct: 199 PFEDPDDPKNFRKTIGRIVSIQYKIPEYVHISQDCRQLLSRIFVANPAKRITIREIRNHP 258 Query: 389 WIREDGEAPDKPLDITVISRMKQFRAMNKLKKVALKIVAE 508 W + + P ++T ++ K ++ N + + + V E Sbjct: 259 WFMK-----NLPRELTEAAQAKYYKKDNSARTFSDQTVDE 293
>SN1L2_PONPY (Q5REX1) Serine/threonine-protein kinase SNF1-like kinase 2 (EC| 2.7.11.1) Length = 925 Score = 76.3 bits (186), Expect = 6e-14 Identities = 50/133 (37%), Positives = 67/133 (50%), Gaps = 2/133 (1%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRRY--GAEADIWS 175 EN L N +K DF FFK GE GS Y APEV + + G + DIWS Sbjct: 146 ENLLLDNNMN---IKIADFSFGNFFKSGELLATWRGSPPYAAPEVFEGQQYEGPQLDIWS 202 Query: 176 AGVILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKE 355 GV+LY+L+ G PF + VL+G P+ +S + L++RML DP + Sbjct: 203 MGVVLYVLVCGALPFDGPTLPILRQRVLEGRFRI---PY-FMSEDCEHLIRRMLVLDPSK 258 Query: 356 RLTAAEILNHPWI 394 RLT A+I H W+ Sbjct: 259 RLTIAQIKEHKWM 271
>CDC5_YEAST (P32562) Cell cycle serine/threonine-protein kinase CDC5/MSD2 (EC| 2.7.11.21) Length = 705 Score = 76.3 bits (186), Expect = 6e-14 Identities = 58/174 (33%), Positives = 87/174 (50%), Gaps = 11/174 (6%) Frame = +2 Query: 41 LKATDFGLS-VFFKPGEQFRDLVGSAYYVAPEVLKRRYGA---EADIWSAGVILYILLSG 208 LK DFGL+ V E+ + G+ Y+APEVL ++ E DIWS GV+LY LL G Sbjct: 218 LKIGDFGLAAVLANESERKYTICGTPNYIAPEVLMGKHSGHSFEVDIWSLGVMLYALLIG 277 Query: 209 VPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHP 388 PPF A + I++ + F D IS+ K L++ +L DP ER + EI+++ Sbjct: 278 KPPFQARDVNTIYERIKCRDFSFPRD--KPISDEGKILIRDILSLDPIERPSLTEIMDYV 335 Query: 389 WIREDGEAPDKPLDITVISRMKQFR-------AMNKLKKVALKIVAESLSEEEI 529 W R G P + TV+S F +N + ++ ES+S ++I Sbjct: 336 WFR--GTFPPS-IPSTVMSEAPNFEDIPEEQSLVNFKDCMEKSLLLESMSSDKI 386
>GIN4_YEAST (Q12263) Serine/threonine-protein kinase GIN4 (EC 2.7.11.1)| Length = 1142 Score = 75.9 bits (185), Expect = 8e-14 Identities = 48/137 (35%), Positives = 73/137 (53%), Gaps = 4/137 (2%) Frame = +2 Query: 2 ENFLFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKR--RYGAEADIWS 175 EN L +K +K DFG++ G+ GS +Y APE++ G +D+WS Sbjct: 160 ENLLLDHKYN---IKIADFGMAALETEGKLLETSCGSPHYAAPEIVSGIPYQGFASDVWS 216 Query: 176 AGVILYILLSGVPPFWAE--NEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDP 349 GVIL+ LL+G PF E N + V KG + SD IS A+DL++++L DP Sbjct: 217 CGVILFALLTGRLPFDEEDGNIRTLLLKVQKGEFEMPSDD--EISREAQDLIRKILTVDP 274 Query: 350 KERLTAAEILNHPWIRE 400 + R+ +IL HP +++ Sbjct: 275 ERRIKTRDILKHPLLQK 291
>KS6B2_HUMAN (Q9UBS0) Ribosomal protein S6 kinase beta-2 (EC 2.7.11.1) (S6K2)| (70 kDa ribosomal protein S6 kinase 2) (p70-S6KB) (p70 ribosomal S6 kinase beta) (p70 S6Kbeta) (p70 S6 kinase beta) (S6K-beta) (p70-beta) (S6 kinase-related kinase) (SRK) (Serin Length = 482 Score = 75.5 bits (184), Expect = 1e-13 Identities = 43/126 (34%), Positives = 69/126 (54%), Gaps = 7/126 (5%) Frame = +2 Query: 41 LKATDFGL-SVFFKPGEQFRDLVGSAYYVAPEVLKRR-YGAEADIWSAGVILYILLSGVP 214 +K TDFGL G G+ Y+APE+L R + D WS G ++Y +L+G P Sbjct: 208 IKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEILVRSGHNRAVDWWSLGALMYDMLTGSP 267 Query: 215 PFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERL-----TAAEIL 379 PF AEN + D +++G + P ++ A+DLVK+ L+++P +R+ AA++ Sbjct: 268 PFTAENRKKTMDKIIRGKLALP----PYLTPDARDLVKKFLKRNPSQRIGGGPGDAADVQ 323 Query: 380 NHPWIR 397 HP+ R Sbjct: 324 RHPFFR 329
>ST17B_HUMAN (O94768) Serine/threonine-protein kinase 17B (EC 2.7.11.1) (DAP| kinase-related apoptosis-inducing protein kinase 2) Length = 372 Score = 75.1 bits (183), Expect = 1e-13 Identities = 37/121 (30%), Positives = 73/121 (60%), Gaps = 1/121 (0%) Frame = +2 Query: 41 LKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRRYGAEA-DIWSAGVILYILLSGVPP 217 +K DFG+S + R+++G+ Y+APE+L A D+W+ G+I Y+LL+ P Sbjct: 175 IKIVDFGMSRKIGHACELREIMGTPEYLAPEILNYDPITTATDMWNIGIIAYMLLTHTSP 234 Query: 218 FWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHPWIR 397 F E+ + + + + ++D+S + + S+S A D ++ +L ++P++R TA L+H W++ Sbjct: 235 FVGEDNQETYLNISQVNVDYSEETFSSVSQLATDFIQSLLVKNPEKRPTAEICLSHSWLQ 294 Query: 398 E 400 + Sbjct: 295 Q 295
>PRKX_HUMAN (P51817) Serine/threonine-protein kinase PRKX (EC 2.7.11.1)| (Protein kinase PKX1) Length = 358 Score = 75.1 bits (183), Expect = 1e-13 Identities = 49/148 (33%), Positives = 81/148 (54%), Gaps = 8/148 (5%) Frame = +2 Query: 32 DSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRR-YGAEADIWSAGVILYILLSG 208 D +K TDFG + K ++ L G+ Y+APEV++ + +G D W+ G++++ +LSG Sbjct: 183 DGHIKLTDFGFAK--KLVDRTWTLCGTPEYLAPEVIQSKGHGRAVDWWALGILIFEMLSG 240 Query: 209 VPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERL-----TAAE 373 PPF+ +N GI+ +L G IDF + KDL+K++L D RL A + Sbjct: 241 FPPFFDDNPFGIYQKILAGKIDFPR----HLDFHVKDLIKKLLVVDRTRRLGNMKNGAND 296 Query: 374 ILNHPWIRE-DGEA-PDKPLDITVISRM 451 + +H W R D EA P + L ++ ++ Sbjct: 297 VKHHRWFRSVDWEAVPQRKLKPPIVPKI 324
>IPL1_YARLI (Q6C3J2) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 371 Score = 75.1 bits (183), Expect = 1e-13 Identities = 43/119 (36%), Positives = 62/119 (52%), Gaps = 1/119 (0%) Frame = +2 Query: 41 LKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRR-YGAEADIWSAGVILYILLSGVPP 217 +K +DFG SV P + L G+ Y+ PE+++ R Y D+WS G+++Y L G PP Sbjct: 236 IKISDFGWSVH-APSNRRSTLCGTMDYLPPEIVQSRPYDKNVDVWSLGILMYEFLCGAPP 294 Query: 218 FWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHPWI 394 F E G A + + P +S A DL+KRML DP +R ++ HPWI Sbjct: 295 F---EEPGGAQATYRRIVKLDLRIPPYVSADAADLIKRMLTLDPAKRFKLKDMHKHPWI 350
>ATG1_NEUCR (Q7RX99) Serine/threonine-protein kinase atg-1 (EC 2.7.11.1)| (Autophagy-related protein 1) Length = 932 Score = 75.1 bits (183), Expect = 1e-13 Identities = 39/121 (32%), Positives = 64/121 (52%), Gaps = 1/121 (0%) Frame = +2 Query: 41 LKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLK-RRYGAEADIWSAGVILYILLSGVPP 217 LK DFG + L GS Y+APE+L+ +Y A+AD+WS G +LY +++G PP Sbjct: 211 LKLADFGFARVLPSTSLAETLCGSPLYMAPEILRYEKYDAKADLWSVGTVLYEMVTGRPP 270 Query: 218 FWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHPWIR 397 F A N + + +S K L++ +L+++P ER++ ++ NHP + Sbjct: 271 FKASNHVELLRKIESSGDVIKFTRESVVSQEMKGLIRALLKKNPVERISFEDLFNHPVVT 330 Query: 398 E 400 E Sbjct: 331 E 331
>PLK4_MOUSE (Q64702) Serine/threonine-protein kinase PLK4 (EC 2.7.11.21)| (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase Sak) (Serine/threonine-protein kinase 18) Length = 925 Score = 75.1 bits (183), Expect = 1e-13 Identities = 41/129 (31%), Positives = 72/129 (55%), Gaps = 2/129 (1%) Frame = +2 Query: 41 LKATDFGLSVFFK-PGEQFRDLVGSAYYVAPEVLKRR-YGAEADIWSAGVILYILLSGVP 214 +K DFGL+ P E+ L G+ Y++PE+ R +G E+DIWS G + Y LL G P Sbjct: 150 IKIADFGLATQLNMPHEKHYTLCGTPNYISPEIATRSAHGLESDIWSLGCMFYTLLIGRP 209 Query: 215 PFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHPWI 394 PF + + + V+ + + +S A+DL+ ++LR++P +RL+ + +L+HP++ Sbjct: 210 PFDTDTVKNTLNKVVLADYEMPA----FLSREAQDLIHQLLRRNPADRLSLSSVLDHPFM 265 Query: 395 REDGEAPDK 421 + K Sbjct: 266 SRNPSPKSK 274
>SNF1_CANGA (Q00372) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 612 Score = 75.1 bits (183), Expect = 1e-13 Identities = 55/168 (32%), Positives = 79/168 (47%), Gaps = 2/168 (1%) Frame = +2 Query: 41 LKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRRY--GAEADIWSAGVILYILLSGVP 214 +K DFGLS G + GS Y APEV+ + G E D+WS GVILY++L Sbjct: 175 VKIADFGLSNIMTDGNFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYVMLCRRL 234 Query: 215 PFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHPWI 394 PF E+ +F + G +S GA DL+KRML +P R++ EI+ W Sbjct: 235 PFDDESIPVLFKNISNGVYTLPK----FLSPGASDLIKRMLIVNPLNRISIHEIMQDEWF 290 Query: 395 REDGEAPDKPLDITVISRMKQFRAMNKLKKVALKIVAESLSEEEIVGL 538 + D P D + + +QF KK + E + +E +V L Sbjct: 291 KVDLAEYLVPQD---LKQQEQFN-----KKSGNEENVEEIDDEMVVTL 330
>CHK1_SCHPO (P34208) Serine/threonine-protein kinase chk1 (EC 2.7.11.1)| (Checkpoint kinase 1) Length = 496 Score = 75.1 bits (183), Expect = 1e-13 Identities = 46/123 (37%), Positives = 66/123 (53%), Gaps = 5/123 (4%) Frame = +2 Query: 41 LKATDFGLSVFFKPGEQFRDL---VGSAYYVAPEVLKRRYGAEADIWSAGVILYILLSGV 211 LK +DFG + F + R L VGS Y APE+ ++ G++ D+WS G+IL+ LL G Sbjct: 151 LKISDFGFASLFSYKGKSRLLNSPVGSPPYAAPEITQQYDGSKVDVWSCGIILFALLLGN 210 Query: 212 PPFWAENEEGIFDAVL--KGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNH 385 P W E D +L K S PW +S GA ++ MLR DP +R + ++ H Sbjct: 211 TP-WDEAISNTGDYLLYKKQCERPSYHPWNLLSPGAYSIITGMLRSDPFKRYSVKHVVQH 269 Query: 386 PWI 394 PW+ Sbjct: 270 PWL 272
>AURKB_RAT (O55099) Serine/threonine-protein kinase 12 (EC 2.7.11.1) (Aurora-| and Ipl1-like midbody-associated protein 1) (AIM-1) (Aurora-B) Length = 343 Score = 75.1 bits (183), Expect = 1e-13 Identities = 41/120 (34%), Positives = 68/120 (56%), Gaps = 1/120 (0%) Frame = +2 Query: 41 LKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRRYGAE-ADIWSAGVILYILLSGVPP 217 LK DFG SV P + + + G+ Y+ PE+++ R E D+W GV+ Y L+ G PP Sbjct: 217 LKIADFGWSVH-APSLRRKTMCGTLDYLPPEMIEGRMHNEMVDLWCIGVLCYELMVGNPP 275 Query: 218 FWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHPWIR 397 F + + + ++K + F S S+ GAKDL+ ++L+ +P +RL ++ HPW+R Sbjct: 276 FESPSHSETYRRIVKVDLKFPS----SMPLGAKDLISKLLKHNPSQRLPLEQVSAHPWVR 331
>KGP25_DROME (P32023) cGMP-dependent protein kinase, isozyme 2 forms cD5/T2 (EC| 2.7.11.12) (CGK) (Foraging protein) Length = 934 Score = 74.7 bits (182), Expect = 2e-13 Identities = 49/133 (36%), Positives = 72/133 (54%), Gaps = 6/133 (4%) Frame = +2 Query: 11 LFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEV-LKRRYGAEADIWSAGVI 187 L LN+R +K DFG + + G + G+ YVAPEV L R + AD WS GV+ Sbjct: 753 LLLNER--GYVKLVDFGFAKKLQTGRKTWTFCGTPEYVAPEVILNRGHDISADYWSLGVL 810 Query: 188 LYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERL-- 361 ++ LL+G PPF + ++ +LKG ID P +I+ A +L+K++ R +P ERL Sbjct: 811 MFELLTGTPPFTGSDPMRTYNIILKG-IDAIEFP-RNITRNASNLIKKLCRDNPAERLGY 868 Query: 362 ---TAAEILNHPW 391 +EI H W Sbjct: 869 QRGGISEIQKHKW 881
>CHK1_USTMA (P0C198) Serine/threonine-protein kinase CHK1 (EC 2.7.11.1)| (Checkpoint kinase 1) Length = 662 Score = 74.7 bits (182), Expect = 2e-13 Identities = 46/125 (36%), Positives = 67/125 (53%), Gaps = 6/125 (4%) Frame = +2 Query: 41 LKATDFGLSVFFKPGEQFRDLVG---SAYYVAPEVLKRRY-GAEADIWSAGVILYILLSG 208 LK DFGL +K + R+L G S Y+APE+ + Y G D+WS+GV+L+ +L G Sbjct: 207 LKIADFGLCSVYKYKGKERELTGACGSLPYIAPEMNGKPYRGEPVDVWSSGVVLFAMLVG 266 Query: 209 VPPFWAE--NEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILN 382 P W E + + A G + F DPWP I A L+K+M+ P++R+T I Sbjct: 267 STP-WDEPTSRSPEYSAYRTGKL-FEYDPWPRIPQDALSLLKKMMHPTPEKRITFEGIRR 324 Query: 383 HPWIR 397 H W + Sbjct: 325 HRWFK 329
>KGP24_DROME (Q03043) cGMP-dependent protein kinase, isozyme 2 forms| cD4/T1/T3A/T3B (EC 2.7.11.12) (CGK) (Foraging protein) Length = 1088 Score = 74.7 bits (182), Expect = 2e-13 Identities = 49/133 (36%), Positives = 72/133 (54%), Gaps = 6/133 (4%) Frame = +2 Query: 11 LFLNKREDSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEV-LKRRYGAEADIWSAGVI 187 L LN+R +K DFG + + G + G+ YVAPEV L R + AD WS GV+ Sbjct: 907 LLLNER--GYVKLVDFGFAKKLQTGRKTWTFCGTPEYVAPEVILNRGHDISADYWSLGVL 964 Query: 188 LYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERL-- 361 ++ LL+G PPF + ++ +LKG ID P +I+ A +L+K++ R +P ERL Sbjct: 965 MFELLTGTPPFTGSDPMRTYNIILKG-IDAIEFP-RNITRNASNLIKKLCRDNPAERLGY 1022 Query: 362 ---TAAEILNHPW 391 +EI H W Sbjct: 1023 QRGGISEIQKHKW 1035
>KKCC2_RAT (O88831) Calcium/calmodulin-dependent protein kinase kinase 2 (EC| 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-kinase kinase beta) (CaM-KK beta) (CaMKK beta) Length = 587 Score = 74.3 bits (181), Expect = 2e-13 Identities = 48/178 (26%), Positives = 83/178 (46%), Gaps = 9/178 (5%) Frame = +2 Query: 29 EDSPLKATDFGLSVFFKPGEQF-RDLVGSAYYVAPEVLKRRY----GAEADIWSAGVILY 193 ED +K DFG+S FK + + VG+ ++APE L G D+W+ GV LY Sbjct: 321 EDGHIKIADFGVSNEFKGSDALLSNTVGTPAFMAPESLSETRKIFSGKALDVWAMGVTLY 380 Query: 194 ILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAE 373 + G PF E + + ++F P I+ KDL+ RML ++P+ R+ E Sbjct: 381 CFVFGQCPFMDERIMCLHSKIKSQALEFPDQP--DIAEDLKDLITRMLDKNPESRIVVPE 438 Query: 374 ILNHPWIREDGEAP----DKPLDITVISRMKQFRAMNKLKKVALKIVAESLSEEEIVG 535 I HPW+ G P D+ + ++ + ++ + +A I+ +++ + G Sbjct: 439 IKLHPWVTRHGAEPLPSEDENCTLVEVTEEEVENSVKHIPSLATVILVKTMIRKRSFG 496
>SNF1_SCHPO (O74536) SNF1-like protein kinase ssp2 (EC 2.7.11.1)| Length = 576 Score = 74.3 bits (181), Expect = 2e-13 Identities = 53/183 (28%), Positives = 85/183 (46%), Gaps = 10/183 (5%) Frame = +2 Query: 41 LKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRRY--GAEADIWSAGVILYILLSGVP 214 +K DFGLS G + GS Y APEV+ + G E D+WS G++LY++L G Sbjct: 170 VKIADFGLSNIMTDGNFLKTSCGSPNYAAPEVINGKLYAGPEVDVWSCGIVLYVMLVGRL 229 Query: 215 PFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHPW- 391 PF E +F V + D +S GA+ L++RM+ DP +R+T EI PW Sbjct: 230 PFDDEFIPNLFKKV-NSCVYVMPD---FLSPGAQSLIRRMIVADPMQRITIQEIRRDPWF 285 Query: 392 -------IREDGEAPDKPLDITVISRMKQFRAMNKLKKVALKIVAESLSEEEIVGLREMF 550 +R E D ++S++ + ++ + E+L +E ++E + Sbjct: 286 NVNLPDYLRPMEEVQGSYADSRIVSKLGEAMGFSE------DYIVEALRSDENNEVKEAY 339 Query: 551 KSL 559 L Sbjct: 340 NLL 342
>AAIP_WHEAT (Q02066) Abscisic acid-inducible protein kinase (EC 2.7.11.1)| (Fragment) Length = 332 Score = 74.3 bits (181), Expect = 2e-13 Identities = 45/121 (37%), Positives = 63/121 (52%), Gaps = 4/121 (3%) Frame = +2 Query: 41 LKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRRY--GAEADIWSAGVILYILLSGVP 214 LK DFG S Q + VG+ Y+APEVL RR G AD+WS GV LY++L G Sbjct: 129 LKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAY 188 Query: 215 PFWAENEEGIFDAVLKG--HIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHP 388 PF +E F + + +S + +S L+ R+ +P++R+T EI NHP Sbjct: 189 PFEDPDEPRNFRKTITRILSVQYSVPDYVRVSMDCIHLLSRIFVGNPQQRITIPEIKNHP 248 Query: 389 W 391 W Sbjct: 249 W 249
>SAPK7_ORYSA (Q7XQP4) Serine/threonine-protein kinase SAPK7 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 7) Length = 359 Score = 74.3 bits (181), Expect = 2e-13 Identities = 48/160 (30%), Positives = 78/160 (48%), Gaps = 4/160 (2%) Frame = +2 Query: 41 LKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRRY--GAEADIWSAGVILYILLSGVP 214 LK DFG S + + VG+ Y+APEVL RR G AD+WS GV LY++L G Sbjct: 139 LKICDFGYSKSSLLHSKPKSTVGTPAYIAPEVLSRREYDGKTADVWSCGVTLYVMLVGAY 198 Query: 215 PFWAENEEGIFDAVLKG--HIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHP 388 PF ++ F + I + + +S + L+ R+ +P +R+T EI NHP Sbjct: 199 PFEDPDDPKNFRKTIGRIMSIQYKIPEYVHVSQDCRQLLSRIFVANPAKRITIREIRNHP 258 Query: 389 WIREDGEAPDKPLDITVISRMKQFRAMNKLKKVALKIVAE 508 W + + P ++T ++ ++ N +++ V E Sbjct: 259 WFLK-----NLPRELTEAAQAMYYKKDNSAPTYSVQSVEE 293
>KKCC2_MOUSE (Q8C078) Calcium/calmodulin-dependent protein kinase kinase 2 (EC| 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-kinase kinase beta) (CaM-KK beta) (CaMKK beta) Length = 588 Score = 74.3 bits (181), Expect = 2e-13 Identities = 48/178 (26%), Positives = 83/178 (46%), Gaps = 9/178 (5%) Frame = +2 Query: 29 EDSPLKATDFGLSVFFKPGEQF-RDLVGSAYYVAPEVLKRRY----GAEADIWSAGVILY 193 ED +K DFG+S FK + + VG+ ++APE L G D+W+ GV LY Sbjct: 322 EDGHIKIADFGVSNEFKGSDALLSNTVGTPAFMAPESLSETRKIFSGKALDVWAMGVTLY 381 Query: 194 ILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAE 373 + G PF E + + ++F P I+ KDL+ RML ++P+ R+ E Sbjct: 382 CFVFGQCPFMDERIMCLHSKIKSQALEFPDQP--DIAEDLKDLITRMLDKNPESRIVVPE 439 Query: 374 ILNHPWIREDGEAP----DKPLDITVISRMKQFRAMNKLKKVALKIVAESLSEEEIVG 535 I HPW+ G P D+ + ++ + ++ + +A I+ +++ + G Sbjct: 440 IKLHPWVTRHGAEPLPSEDENCTLVEVTEEEVENSVKHIPSLATVILVKTMIRKRSFG 497
>KKCC2_HUMAN (Q96RR4) Calcium/calmodulin-dependent protein kinase kinase 2 (EC| 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-kinase kinase beta) (CaM-KK beta) (CaMKK beta) Length = 588 Score = 74.3 bits (181), Expect = 2e-13 Identities = 48/178 (26%), Positives = 83/178 (46%), Gaps = 9/178 (5%) Frame = +2 Query: 29 EDSPLKATDFGLSVFFKPGEQF-RDLVGSAYYVAPEVLKRRY----GAEADIWSAGVILY 193 ED +K DFG+S FK + + VG+ ++APE L G D+W+ GV LY Sbjct: 322 EDGHIKIADFGVSNEFKGSDALLSNTVGTPAFMAPESLSETRKIFSGKALDVWAMGVTLY 381 Query: 194 ILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAE 373 + G PF E + + ++F P I+ KDL+ RML ++P+ R+ E Sbjct: 382 CFVFGQCPFMDERIMCLHSKIKSQALEFPDQP--DIAEDLKDLITRMLDKNPESRIVVPE 439 Query: 374 ILNHPWIREDGEAP----DKPLDITVISRMKQFRAMNKLKKVALKIVAESLSEEEIVG 535 I HPW+ G P D+ + ++ + ++ + +A I+ +++ + G Sbjct: 440 IKLHPWVTRHGAEPLPSEDENCTLVEVTEEEVENSVKHIPSLATVILVKTMIRKRSFG 497
>SNF1_CANAL (P52497) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 620 Score = 74.3 bits (181), Expect = 2e-13 Identities = 47/124 (37%), Positives = 65/124 (52%), Gaps = 3/124 (2%) Frame = +2 Query: 41 LKATDFGLSVFFKPGEQFRDLVGSAYYV-APEVLKRRY--GAEADIWSAGVILYILLSGV 211 +K DFGLS G + GS Y+ APEV+ + G E D+WSAGVILY++L G Sbjct: 189 VKIADFGLSNIMTDGNFLKTSCGSPNYMPAPEVISGKLYAGPEVDVWSAGVILYVMLCGR 248 Query: 212 PPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHPW 391 PF E +F + G + +S GAK L+ RML +P R+T EI+ W Sbjct: 249 LPFDDEFIPALFKKISNGVYTLPN----YLSAGAKHLLTRMLVVNPLNRITIHEIMEDDW 304 Query: 392 IRED 403 ++D Sbjct: 305 FKQD 308
>SAPKA_ORYSA (Q75H77) Serine/threonine-protein kinase SAPK10 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 10) Length = 362 Score = 74.3 bits (181), Expect = 2e-13 Identities = 46/121 (38%), Positives = 65/121 (53%), Gaps = 4/121 (3%) Frame = +2 Query: 41 LKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVL-KRRY-GAEADIWSAGVILYILLSGVP 214 LK DFG S Q + VG+ Y+APEVL K+ Y G AD+WS GV LY++L G Sbjct: 158 LKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYDGKIADVWSCGVTLYVMLVGAY 217 Query: 215 PFWAENEEGIFDAVLKG--HIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHP 388 PF +E F ++ + +S + IS +DL+ R+ +P R++ EI NHP Sbjct: 218 PFEDPDEPKNFRKTIQRILGVQYSIPDYVHISPECRDLIARIFVANPATRISIPEIRNHP 277 Query: 389 W 391 W Sbjct: 278 W 278
>KS6B2_MOUSE (Q9Z1M4) Ribosomal protein S6 kinase beta-2 (EC 2.7.11.1) (S6K-beta| 2) (70 kDa ribosomal protein S6 kinase 2) (p70-S6KB) (p70 ribosomal S6 kinase beta) (p70 S6Kbeta) (S6K2) Length = 485 Score = 73.9 bits (180), Expect = 3e-13 Identities = 43/126 (34%), Positives = 68/126 (53%), Gaps = 7/126 (5%) Frame = +2 Query: 41 LKATDFGL-SVFFKPGEQFRDLVGSAYYVAPEVLKRR-YGAEADIWSAGVILYILLSGVP 214 +K TDFGL G G+ Y+APE+L R + D WS G ++Y +L+G P Sbjct: 208 IKLTDFGLCKESIHEGAITHTFCGTIEYMAPEILVRTGHNRAVDWWSLGALMYDMLTGSP 267 Query: 215 PFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERL-----TAAEIL 379 PF AEN + D ++KG + P ++ A+DL K+ L+++P +R+ AA++ Sbjct: 268 PFTAENRKKTMDKIIKGKLVLP----PYLTPDARDLAKKFLKRNPTQRIGGGLGDAADVQ 323 Query: 380 NHPWIR 397 HP+ R Sbjct: 324 RHPFFR 329
>SSP1_SCHPO (P50526) Serine/threonine-protein kinase ssp1 (EC 2.7.11.1)| Length = 652 Score = 73.9 bits (180), Expect = 3e-13 Identities = 47/154 (30%), Positives = 79/154 (51%), Gaps = 16/154 (10%) Frame = +2 Query: 41 LKATDFGLSVFFKPG------EQFRDLVGSAYYVAPEVL-------KRRYGAEADIWSAG 181 +K +DFG+S G + VG+ + APE+ + + D+W+ G Sbjct: 281 VKISDFGVSYIANAGLNEDNDVELAKTVGTPAFFAPELCWTDLDRPRPKISEAIDVWALG 340 Query: 182 VILYILLSGVPPFWAENEEGIFDAVLKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERL 361 V L+ LL G PF A E +FD ++ ++ S P I +DL+KR+L +DP++R+ Sbjct: 341 VTLFCLLFGRCPFNASMEYELFDKIVNERLNIPSTP--DIGEEGRDLLKRLLCKDPEQRI 398 Query: 362 TAAEILNHPWIREDGEAPDKPL---DITVISRMK 454 T E+ HPW + + P+K L D + +SR++ Sbjct: 399 TLVEVKLHPWTLDGLKDPEKWLQNTDPSTVSRVE 432
>DUET_HUMAN (Q9Y2A5) Serine/threonine-protein kinase Duet (EC 2.7.11.1)| (Serine/threonine kinase with Dbl- and pleckstrin homology domain) Length = 1289 Score = 73.9 bits (180), Expect = 3e-13 Identities = 41/112 (36%), Positives = 64/112 (57%), Gaps = 2/112 (1%) Frame = +2 Query: 101 LVGSAYYVAPEVLKR-RYGAEADIWSAGVILYILLSGVPPFWAENEEGIFDAVLKGHIDF 277 L+G+ + APEV++ DIWS GV+ Y++LSGV PF E++E V + F Sbjct: 1143 LLGNPEFAAPEVIQGIPVSLGTDIWSIGVLTYVMLSGVSPFLDESKEETCINVCRVDFSF 1202 Query: 278 SSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHPWIR-EDGEAPDKPLD 430 + + +SN A+D + +L++D + R TAA L HPW++ +G PLD Sbjct: 1203 PHEYFCGVSNAARDFINVILQEDFRRRPTAATCLQHPWLQPHNGSYSKIPLD 1254
>SAPK1_ORYSA (Q75LR7) Serine/threonine-protein kinase SAPK1 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 1) Length = 342 Score = 73.9 bits (180), Expect = 3e-13 Identities = 43/121 (35%), Positives = 64/121 (52%), Gaps = 4/121 (3%) Frame = +2 Query: 41 LKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVLKRRY--GAEADIWSAGVILYILLSGVP 214 LK DFG S Q + VG+ Y+APEVL R+ G AD+WS GV LY++L G Sbjct: 139 LKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLVGAY 198 Query: 215 PFWAENEEGIFDAVLKG--HIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHP 388 PF ++ F + + +S + +S + L+ R+ +P++R+T EI NHP Sbjct: 199 PFEDPDDPRNFRKTITRILSVQYSIPDYVRVSADCRHLLSRIFVGNPEQRITIPEIKNHP 258 Query: 389 W 391 W Sbjct: 259 W 259
>MARK3_RAT (Q8VHF0) MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1)| Length = 797 Score = 73.9 bits (180), Expect = 3e-13 Identities = 49/130 (37%), Positives = 68/130 (52%), Gaps = 4/130 (3%) Frame = +2 Query: 32 DSPLKATDFGLSVFFKPGEQFRDLVGSAYYVAPEVL--KRRYGAEADIWSAGVILYILLS 205 D +K TDFG S F G + GS Y APE+ K+ G E D+WS GVILY L+S Sbjct: 189 DMNIKITDFGFSNEFTVGSKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVS 248 Query: 206 GVPPFWAENEEGIFDAVLKG--HIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEIL 379 G PF +N + + + VL+G I F +S ++L+KR L +P +R T +I+ Sbjct: 249 GSLPFDGQNLKELRERVLRGKYRIPF------YMSTDCENLLKRFLVLNPVKRGTLEQIM 302 Query: 380 NHPWIREDGE 409 WI E Sbjct: 303 KDRWINAGHE 312
>TRIB2_BOVIN (Q5GLH2) Tribbles homolog 2 (TRB-2)| Length = 343 Score = 73.9 bits (180), Expect = 3e-13 Identities = 40/109 (36%), Positives = 59/109 (54%), Gaps = 3/109 (2%) Frame = +2 Query: 86 EQFRDLVGSAYYVAPEVLKRR---YGAEADIWSAGVILYILLSGVPPFWAENEEGIFDAV 256 + D G YV+PE+L G AD+WS GV+LY +L G PF +F + Sbjct: 207 DSLSDKHGCPAYVSPEILNTNGSYSGKAADVWSLGVMLYTMLVGRYPFHDIEPSSLFSKI 266 Query: 257 LKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHPWIRED 403 +G + ++S AK L++ +LR++P ERLT+ EIL+HPW D Sbjct: 267 RRGQFNIPE----TLSPKAKCLIRSILRREPSERLTSQEILDHPWFSTD 311
>TRIB2_PONPY (Q5R669) Tribbles homolog 2 (TRB-2)| Length = 343 Score = 73.6 bits (179), Expect = 4e-13 Identities = 40/109 (36%), Positives = 59/109 (54%), Gaps = 3/109 (2%) Frame = +2 Query: 86 EQFRDLVGSAYYVAPEVLKRR---YGAEADIWSAGVILYILLSGVPPFWAENEEGIFDAV 256 + D G YV+PE+L G AD+WS GV+LY +L G PF +F + Sbjct: 207 DSLSDKHGCPAYVSPEILNTSGSYSGKAADVWSLGVMLYTMLVGRYPFHDIEPSSLFSKI 266 Query: 257 LKGHIDFSSDPWPSISNGAKDLVKRMLRQDPKERLTAAEILNHPWIRED 403 +G + ++S AK L++ +LR++P ERLT+ EIL+HPW D Sbjct: 267 RRGQFNIPE----TLSPKAKCLIRSILRREPSERLTSQEILDHPWFSTD 311 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 88,151,949 Number of Sequences: 219361 Number of extensions: 1905173 Number of successful extensions: 8852 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 7392 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 7914 length of database: 80,573,946 effective HSP length: 107 effective length of database: 57,102,319 effective search space used: 5253413348 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
