ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | basd27h17 |
|---|---|
| Clone Library Name | barley_pub |
>MYH9_MOUSE (Q8VDD5) Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle| myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A) Length = 1959 Score = 57.8 bits (138), Expect = 3e-08 Identities = 50/201 (24%), Positives = 86/201 (42%), Gaps = 8/201 (3%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKW-------- 160 E L S+ +K L ++L ++ ELE + A Q+E S RE + Sbjct: 1117 EDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVSILKKTLE 1176 Query: 161 DAYKTYSADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKL 340 D KT+ A E+ QKH+ +E L+Q + K K E+E+ L N ++ L Sbjct: 1177 DEAKTHEAQIQEMRQKHSQAVEELADQLEQTKRVKATLEKAKQTLENERGELAN-EVKAL 1235 Query: 341 TQNVSKSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQ 520 Q S KKV+ Q+LQ+ +S+ + + + LDS+T + D Sbjct: 1236 LQGKGDSEHKRKKVEAQLQELQVKFSEGERVRTELADKVTKLQVELDSVTGLLSQSDSKS 1295 Query: 521 APSTASVNPAQQQLREPSGIM 583 + T + + QL++ ++ Sbjct: 1296 SKLTKDFSALESQLQDTQELL 1316 Score = 46.6 bits (109), Expect = 6e-05 Identities = 38/149 (25%), Positives = 72/149 (48%), Gaps = 6/149 (4%) Frame = +2 Query: 11 LTSKMQEHANLVHEKDQL---EQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYS 181 L +K++ N + +D+L E +L +VR++ AA + E S + A K Sbjct: 829 LFTKVKPLLNSIRHEDELLAKEAELTKVREKHLAAENRLTEMETMQS----QLMAEKLQL 884 Query: 182 ADQLEVAQK---HAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNV 352 +QL+ + A EL +++A Q+L+E + +V EE E+ + + K+ QN+ Sbjct: 885 QEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQYLQAEKKKMQQNI 944 Query: 353 SKSAEMEKKVQDLEQKLQLAYSKSDEQAK 439 + E ++ + QKLQL ++ + K Sbjct: 945 QELEEQLEEEESARQKLQLEKVTTEAKLK 973 Score = 43.5 bits (101), Expect = 5e-04 Identities = 44/218 (20%), Positives = 103/218 (47%), Gaps = 26/218 (11%) Frame = +2 Query: 11 LTSKMQEHANLVHEKDQLEQQLLEVRK-------ELEAAYRTIANQEEQASVREIKWDAY 169 L ++ E + E+++ + L +++ +LE R Q ++ K + Sbjct: 996 LEDRVAEFTTNLMEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGD 1055 Query: 170 KTYSADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEES---EKLALVNTQLNKL 340 T +DQ+ Q AEL++Q++ +++LQ A + + A+++ +K+ + TQ+++L Sbjct: 1056 STDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELETQISEL 1115 Query: 341 TQNVSKSA----EMEKKVQDLEQKLQLAYSKSDE-----QAKDAVVSTRSREFSL----- 478 +++ + EK+ +DL ++L+ ++ ++ A+ + S R +E S+ Sbjct: 1116 QEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVSILKKTL 1175 Query: 479 --DSLTPQNKEQDLSQAPSTASVNPAQQQLREPSGIMA 586 ++ T + + Q++ Q S A V QL + + A Sbjct: 1176 EDEAKTHEAQIQEMRQKHSQA-VEELADQLEQTKRVKA 1212
>MYH9_RAT (Q62812) Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle| myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A) Length = 1960 Score = 56.6 bits (135), Expect = 6e-08 Identities = 47/186 (25%), Positives = 82/186 (44%), Gaps = 8/186 (4%) Frame = +2 Query: 50 EKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKW--------DAYKTYSADQLEVAQ 205 +K L ++L ++ ELE + A Q+E S RE + D KT+ A E+ Q Sbjct: 1132 QKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVSILKKTLEDEAKTHEAQIQEMRQ 1191 Query: 206 KHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEMEKKVQ 385 KH+ +E L+Q + K K E+E+ L N ++ L Q S KKV+ Sbjct: 1192 KHSQAVEELAEQLEQTKRVKATLEKAKQTLENERGELAN-EVKALLQGKGDSEHKRKKVE 1250 Query: 386 DLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQAPSTASVNPAQQQLR 565 Q+LQ+ +S+ + + + LDS+T + D + T + + QL+ Sbjct: 1251 AQLQELQVKFSEGERVRTELADKVSKLQVELDSVTGLLNQSDSKSSKLTKDFSALESQLQ 1310 Query: 566 EPSGIM 583 + ++ Sbjct: 1311 DTQELL 1316 Score = 47.8 bits (112), Expect = 3e-05 Identities = 47/212 (22%), Positives = 94/212 (44%), Gaps = 27/212 (12%) Frame = +2 Query: 11 LTSKMQEHANLVHEKDQL---EQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYS 181 L +K++ N + +D+L E +L +VR++ AA + E S + A K Sbjct: 829 LFTKVKPLLNSIRHEDELLAKEAELTKVREKHLAAENRLTEMETMQS----QLMAEKLQL 884 Query: 182 ADQLEVAQK---HAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNV 352 +QL+ + A EL +++A Q+L+E + +V EE E+ + + K+ QN+ Sbjct: 885 QEQLQAKTELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQYLQAEKKKMQQNI 944 Query: 353 SKSAEMEKKVQDLEQKLQLAYSKSDEQAK-------------------DAVVSTRSREFS 475 + E ++ + QKLQL ++ + K ++ R EF+ Sbjct: 945 QELEEQLEEEESARQKLQLEKVTTEAKLKKLEEDQIIMEDQNCKLAKEKKLLEDRVAEFT 1004 Query: 476 LDSLTPQNKEQDLSQAPS--TASVNPAQQQLR 565 D + + K + L++ + A + +++LR Sbjct: 1005 TDLMEEEEKSKSLAKLKNKHEAMITDLEERLR 1036 Score = 43.9 bits (102), Expect = 4e-04 Identities = 44/218 (20%), Positives = 104/218 (47%), Gaps = 26/218 (11%) Frame = +2 Query: 11 LTSKMQEHANLVHEKDQLEQQLLEVRK-------ELEAAYRTIANQEEQASVREIKWDAY 169 L ++ E + E+++ + L +++ +LE R Q ++ K + Sbjct: 996 LEDRVAEFTTDLMEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGD 1055 Query: 170 KTYSADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEES---EKLALVNTQLNKL 340 T +DQ+ Q AEL++Q++ +++LQ A + + A+++ +K+ + TQ+++L Sbjct: 1056 STDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELETQISEL 1115 Query: 341 TQNVSKSA----EMEKKVQDLEQKLQLAYSKSDE-----QAKDAVVSTRSREFSL----- 478 +++ + EK+ +DL ++L+ ++ ++ A+ + S R +E S+ Sbjct: 1116 QEDLESERACRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVSILKKTL 1175 Query: 479 --DSLTPQNKEQDLSQAPSTASVNPAQQQLREPSGIMA 586 ++ T + + Q++ Q S A V +QL + + A Sbjct: 1176 EDEAKTHEAQIQEMRQKHSQA-VEELAEQLEQTKRVKA 1212
>EEA1_HUMAN (Q15075) Early endosome antigen 1 (Endosome-associated protein| p162) (Zinc finger FYVE domain-containing protein 2) Length = 1411 Score = 55.1 bits (131), Expect = 2e-07 Identities = 54/196 (27%), Positives = 91/196 (46%), Gaps = 7/196 (3%) Frame = +2 Query: 2 NEALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYS 181 NE SK A L H+KD QQL + L A+ ++ + S K +A + Sbjct: 326 NEESVSKKNIQATL-HQKDLDCQQL---QSRLSASETSLHRIHVELSE---KGEATQKLK 378 Query: 182 ADQLEVAQKHAAELEVQVSALDQQLQEAEIH---YKNKVAEESEKLALVNTQLNKLTQNV 352 + EV K+ L+ + L QQ +E E H ++++ + KL QL + + Sbjct: 379 EELSEVETKYQ-HLKAEFKQLQQQREEKEQHGLQLQSEINQLHSKLLETERQLGEAHGRL 437 Query: 353 SKSAEME-KKVQDLEQK---LQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQ 520 + ++ +K+ D EQ+ LQL S+ +EQ K+ V ++ + LD Q++EQ Q Sbjct: 438 KEQRQLSSEKLMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQ 497 Query: 521 APSTASVNPAQQQLRE 568 +TA + AQ L + Sbjct: 498 QSTTAKLREAQNDLEQ 513 Score = 38.5 bits (88), Expect = 0.017 Identities = 43/195 (22%), Positives = 93/195 (47%), Gaps = 7/195 (3%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSA 184 ++L + + L E + +++QL++ + L+ + Q+ Q ++ E+K + + Sbjct: 917 KSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKE--EQQLQGNINELKQSSEQ--KK 972 Query: 185 DQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSA 364 Q+E Q +Q + L+ +LQ+ ++A E EK+++ L N KS Sbjct: 973 KQIEALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKEKISV-------LQNNYEKSQ 1025 Query: 365 EMEKKVQD--LEQKLQLAYSKSDEQAKDAVVSTRSREF--SLDSLTPQNK-EQDLSQAPS 529 E K++Q ++ +L ++ D ++ + +S + + + + QNK Q+L A + Sbjct: 1026 ETFKQLQSDFYGRESELLATRQDLKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKA 1085 Query: 530 TASVNPA--QQQLRE 568 T + A +QQL+E Sbjct: 1086 TLEQDSAKKEQQLQE 1100 Score = 37.0 bits (84), Expect = 0.050 Identities = 37/150 (24%), Positives = 66/150 (44%), Gaps = 6/150 (4%) Frame = +2 Query: 8 ALTSKMQEHANLVHEKDQLEQQLL-EVRKELEAAYRTIANQEEQASVREIKWDAYKTYSA 184 A + +Q H + Q +QQ L ++ +L+ + +++E S E K Y Sbjct: 660 AQRADLQNHLDTAQNALQDKQQELNKITTQLDQVTAKLQDKQEHCSQLE---SHLKEYKE 716 Query: 185 DQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSA 364 L + QK ELE Q+ L+ E + K + ++ ++ +NT L +SK Sbjct: 717 KYLSLEQK-TEELEGQIKKLEADSLEVKAS-KEQALQDLQQQRQLNTDLELRATELSKQL 774 Query: 365 EMEKKV-----QDLEQKLQLAYSKSDEQAK 439 EMEK++ DL++K + S + K Sbjct: 775 EMEKEIVSSTRLDLQKKSEALESIKQKLTK 804 Score = 35.4 bits (80), Expect = 0.14 Identities = 45/194 (23%), Positives = 79/194 (40%), Gaps = 26/194 (13%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQQ--------------LLEVRKELEAAYRTIANQEEQAS 142 E L K+ L H+ D+ +QQ L E + +LE R I +++++ Sbjct: 467 EQLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGDKDQKIQ 526 Query: 143 VREIKWDAYKTYSADQLEVAQKHAAELEVQVSALD------QQLQEAEIHYKNKVAEESE 304 E A S + + + +K +L ++ A + QLQE KN +E Sbjct: 527 NLE----ALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQE-----KNHTLQE-- 575 Query: 305 KLALVNTQLNKLTQNVSKSAEMEKKVQD------LEQKLQLAYSKSDEQAKDAVVSTRSR 466 Q+ +LT+ + +E K+ Q+ EQK L A+D V+S + Sbjct: 576 -------QVTQLTEKLKNQSESHKQAQENLHDQVQEQKAHL------RAAQDRVLSLETS 622 Query: 467 EFSLDSLTPQNKEQ 508 L+S ++KE+ Sbjct: 623 VNELNSQLNESKEK 636
>EEA1_MOUSE (Q8BL66) Early endosome antigen 1| Length = 1411 Score = 54.3 bits (129), Expect = 3e-07 Identities = 53/195 (27%), Positives = 92/195 (47%), Gaps = 6/195 (3%) Frame = +2 Query: 2 NEALTSKMQEHANLVHEKD----QLEQQLLEVRKELEAAYRTIANQEEQAS-VREIKWDA 166 NE S+ A+L H++D QL+ +L L+ A ++ + E A +RE + Sbjct: 326 NEESASRKTLQASL-HQRDLDCQQLQARLTASESSLQRAQGELSEKAEAAQKLREELREV 384 Query: 167 YKTYSADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQ 346 T ++EV Q E + L Q + +++H K + E +L + +L + Q Sbjct: 385 ESTRQHLKVEVKQLQQQREEKEQHGLQLQGEVSQLHCK--LLETERQLGEAHGRLKEQRQ 442 Query: 347 NVS-KSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQA 523 S K E E++V DL+ KL S+ +EQ K+ V ++ + L+ Q++EQ Q Sbjct: 443 LSSEKLMEKEQQVADLQLKL----SRLEEQLKEKVTNSTELQHQLEKSKQQHQEQQALQQ 498 Query: 524 PSTASVNPAQQQLRE 568 +TA + AQ L + Sbjct: 499 SATAKLREAQNDLEQ 513 Score = 32.0 bits (71), Expect = 1.6 Identities = 46/190 (24%), Positives = 80/190 (42%), Gaps = 19/190 (10%) Frame = +2 Query: 53 KDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYK-TYSADQLEVAQKHAAELEV 229 K QL+ Q KE E +++ ++E + +I+ ++ K S Q + QK E ++ Sbjct: 898 KHQLQVQAESALKEQEDLKKSLEKEKETSQQLKIELNSVKGEVSQAQNTLKQKEKDEQQL 957 Query: 230 QVSALDQQLQEAEIHYKNKVAEESEKLALVNTQL---NKLTQNVSKSAE----------- 367 Q ++Q Q AE K A + E V+ + NKL Q S++A+ Sbjct: 958 Q-GTINQLKQSAEQKKKQIEALQGEVKNAVSQKTVLENKLQQQSSQAAQELAAEKGKLSA 1016 Query: 368 ----MEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQAPSTA 535 EK DL+Q Y K E +++TR S++ +E +S Sbjct: 1017 LQSNYEKCQADLKQLQSDLYGKESE-----LLATRQDLKSVEEKLTLAQEDLISNRNQIG 1071 Query: 536 SVNPAQQQLR 565 + N + Q+L+ Sbjct: 1072 NQNKSIQELQ 1081 Score = 30.0 bits (66), Expect = 6.1 Identities = 26/130 (20%), Positives = 60/130 (46%), Gaps = 3/130 (2%) Frame = +2 Query: 26 QEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQ 205 + H L ++ ++L+E +++ ++ EEQ + T QLE ++ Sbjct: 432 EAHGRLKEQRQLSSEKLMEKEQQVADLQLKLSRLEEQLKEKVTN----STELQHQLEKSK 487 Query: 206 KHAAELEVQVSALDQQLQEAEIHYKN---KVAEESEKLALVNTQLNKLTQNVSKSAEMEK 376 + E + + +L+EA+ + ++ ++ +K+ + L K ++VS +EK Sbjct: 488 QQHQEQQALQQSATAKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKGKESVSL---LEK 544 Query: 377 KVQDLEQKLQ 406 + +DL K+Q Sbjct: 545 EREDLYAKIQ 554
>MYH9_CHICK (P14105) Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle| myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A) Length = 1959 Score = 53.5 bits (127), Expect = 5e-07 Identities = 48/201 (23%), Positives = 84/201 (41%), Gaps = 8/201 (3%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKW-------- 160 E L S+ +K L ++L ++ ELE + A Q+E S RE + Sbjct: 1118 EDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVTVLKKTLE 1177 Query: 161 DAYKTYSADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKL 340 D KT+ A E+ QKH+ +E L+Q + K K A ESE+ L N ++ L Sbjct: 1178 DEAKTHEAQIQEMRQKHSQAIEELAEQLEQTKRVKANLEKAKQALESERAELSN-EVKVL 1236 Query: 341 TQNVSKSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQ 520 Q + KKV Q+LQ+ +++ + + + LD++T + D Sbjct: 1237 LQGKGDAEHKRKKVDAQLQELQVKFTEGERVKTELAERVNKLQVELDNVTGLLNQSDSKS 1296 Query: 521 APSTASVNPAQQQLREPSGIM 583 + + QL++ ++ Sbjct: 1297 IKLAKDFSALESQLQDTQELL 1317 Score = 43.1 bits (100), Expect = 7e-04 Identities = 31/126 (24%), Positives = 64/126 (50%), Gaps = 1/126 (0%) Frame = +2 Query: 65 EQQLLEVRKELEAAYRTIANQEE-QASVREIKWDAYKTYSADQLEVAQKHAAELEVQVSA 241 E++L++V+++ AA ++ E QA + K + A+ A+ A E+ +++A Sbjct: 851 EEELIKVKEKQLAAENRLSEMETFQAQLMAEKMQLQEQLQAEAELCAE--AEEIRARLTA 908 Query: 242 LDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEMEKKVQDLEQKLQLAYSK 421 Q+L+E + +V EE E+ + + K+ QN+ + E ++ + QKLQL Sbjct: 909 KKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVT 968 Query: 422 SDEQAK 439 ++ + K Sbjct: 969 TEAKLK 974 Score = 42.4 bits (98), Expect = 0.001 Identities = 41/201 (20%), Positives = 102/201 (50%), Gaps = 19/201 (9%) Frame = +2 Query: 11 LTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQ 190 LT + ++ +L K++ E + ++ + L + QE + + R+++ D+ + DQ Sbjct: 1008 LTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQ--RQELEKTRRKLEGDSSDLH--DQ 1063 Query: 191 LEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEES---EKLALVNTQLNKLTQNVSKS 361 + Q AEL++Q+S +++LQ A + + A+++ +K+ + +Q+ +L +++ Sbjct: 1064 IAELQAQIAELKIQLSKKEEELQAALARVEEEAAQKNMALKKIRELESQITELQEDLESE 1123 Query: 362 A----EMEKKVQDLEQKLQLAYSKSDE-----QAKDAVVSTRSREFSL-------DSLTP 493 + EK+ +DL ++L+ ++ ++ A+ + S R +E ++ ++ T Sbjct: 1124 RASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVTVLKKTLEDEAKTH 1183 Query: 494 QNKEQDLSQAPSTASVNPAQQ 556 + + Q++ Q S A A+Q Sbjct: 1184 EAQIQEMRQKHSQAIEELAEQ 1204 Score = 38.9 bits (89), Expect = 0.013 Identities = 38/179 (21%), Positives = 90/179 (50%), Gaps = 10/179 (5%) Frame = +2 Query: 62 LEQQLLEVRKELEAAYRTI--ANQEEQASVREIKWDAYKTYSADQLEVAQKHAAELEVQV 235 +E +++++++EL AA R A QE EI S+ + +A + LE ++ Sbjct: 1678 MEAEMIQLQEELAAAERAKRQAQQERDELADEI------ANSSGKGALAMEEKRRLEARI 1731 Query: 236 SALDQQLQEAEIHYK---NKVAEESEKLALVNTQLNKLTQNVSKSA----EMEKKVQDLE 394 + L+++L+E + + + +++ + + ++ +N LN N K+ +ME++ ++L+ Sbjct: 1732 AQLEEELEEEQGNTEIINDRLKKANLQIDQMNADLNAERSNAQKNENARQQMERQNKELK 1791 Query: 395 QKLQLAYSKSDEQAKDAVVSTRSREFSL-DSLTPQNKEQDLSQAPSTASVNPAQQQLRE 568 KLQ S + K + + ++ L + L + KE+ ++ V A+++L++ Sbjct: 1792 LKLQEMESAVKSKYKATITALEAKIVQLEEQLDMETKERQ----AASKQVRRAEKKLKD 1846 Score = 37.0 bits (84), Expect = 0.050 Identities = 41/176 (23%), Positives = 76/176 (43%), Gaps = 9/176 (5%) Frame = +2 Query: 2 NEALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYS 181 +++ + K+ + + + + Q Q+LL+ L+ ++ T Q E K Sbjct: 1292 SDSKSIKLAKDFSALESQLQDTQELLQEETRLKLSFSTKLKQTEDE----------KNAL 1341 Query: 182 ADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKN-----KVAEESEKLALVNTQLNKLTQ 346 +QLE ++ LE Q+S L QQ EA + ++AEE++K + L LTQ Sbjct: 1342 KEQLEEEEEAKRNLEKQISVLQQQAVEARKKMDDGLGCLEIAEEAKK--KLQKDLESLTQ 1399 Query: 347 ----NVSKSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNK 502 ++ ++EK L+Q+L D Q + V + ++ D L + K Sbjct: 1400 RYEEKIAAYDKLEKTKTRLQQELDDIAVDLDHQ-RQTVSNLEKKQKKFDQLLAEEK 1454
>MYH9_HUMAN (P35579) Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle| myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A) Length = 1959 Score = 52.8 bits (125), Expect = 9e-07 Identities = 47/201 (23%), Positives = 86/201 (42%), Gaps = 8/201 (3%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIK--------W 160 E L S+ +K L ++L ++ ELE + A Q+E S RE + Sbjct: 1117 EDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLE 1176 Query: 161 DAYKTYSADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKL 340 + KT+ A E+ QKH+ +E L+Q + K K E+E+ L N ++ L Sbjct: 1177 EEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELAN-EVKVL 1235 Query: 341 TQNVSKSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQ 520 Q S KKV+ Q+LQ+ +++ + + + LD++T + D Sbjct: 1236 LQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKS 1295 Query: 521 APSTASVNPAQQQLREPSGIM 583 + T + + QL++ ++ Sbjct: 1296 SKLTKDFSALESQLQDTQELL 1316 Score = 43.5 bits (101), Expect = 5e-04 Identities = 41/186 (22%), Positives = 91/186 (48%) Frame = +2 Query: 11 LTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQ 190 LT + ++ +L K++ E + ++ + L + QE + + R+++ D+ T +DQ Sbjct: 1007 LTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQ--RQELEKTRRKLEGDS--TDLSDQ 1062 Query: 191 LEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEM 370 + Q AEL++Q++ +++LQ A +A E+ A N L K+ + S+ +E+ Sbjct: 1063 IAELQAQIAELKMQLAKKEEELQAA-------LARVEEEAAQKNMALKKIRELESQISEL 1115 Query: 371 EKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQAPSTASVNPA 550 + +DLE + + + +K+++Q +D + + L+ Q ++ VN Sbjct: 1116 Q---EDLESE-RASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNIL 1171 Query: 551 QQQLRE 568 ++ L E Sbjct: 1172 KKTLEE 1177 Score = 43.1 bits (100), Expect = 7e-04 Identities = 33/128 (25%), Positives = 63/128 (49%), Gaps = 3/128 (2%) Frame = +2 Query: 65 EQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQK---HAAELEVQV 235 E++L++VR++ AA + E S + A K +QL+ + A EL ++ Sbjct: 850 EEELVKVREKQLAAENRLTEMETLQS----QLMAEKLQLQEQLQAETELCAEAEELRARL 905 Query: 236 SALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEMEKKVQDLEQKLQLAY 415 +A Q+L+E + +V EE E+ + + K+ QN+ + E ++ + QKLQL Sbjct: 906 TAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEK 965 Query: 416 SKSDEQAK 439 ++ + K Sbjct: 966 VTTEAKLK 973
>SMC4_HUMAN (Q9NTJ3) Structural maintenance of chromosomes 4-like 1 protein| (Chromosome-associated polypeptide C) (hCAP-C) (XCAP-C homolog) Length = 1288 Score = 48.9 bits (115), Expect = 1e-05 Identities = 45/188 (23%), Positives = 85/188 (45%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSA 184 E T+ +Q L+ +++ L Q+ KELEA A +++ + E A+KT Sbjct: 819 EKFTASIQR---LIEQEEYLNVQV----KELEANVLATAPDKKKQKLLEENVSAFKT--- 868 Query: 185 DQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSA 364 + + + A ++E +V L + E H K+ + +KL +N QL++ ++K+ Sbjct: 869 -EYDAVAEKAGKVEAEVKRLHNTIVEINNH---KLKAQQDKLDKINKQLDECASAITKAQ 924 Query: 365 EMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQAPSTASVN 544 K QK Q + +++++ KD E +D LT + K + A + N Sbjct: 925 VAIKTADRNLQKAQDSVLRTEKEIKDT-------EKEVDDLTAELKSLEDKAAEVVKNTN 977 Query: 545 PAQQQLRE 568 A++ L E Sbjct: 978 AAEESLPE 985
>CN145_HUMAN (Q6ZU80) Protein C14orf145| Length = 623 Score = 48.1 bits (113), Expect = 2e-05 Identities = 53/184 (28%), Positives = 88/184 (47%), Gaps = 15/184 (8%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLE-------QQLLEVRKELEAAYRTIANQEEQASVREIKWD 163 + LT K + ++ EKD+L+ QQ+ +RKEL A QEE+ +E K Sbjct: 148 DELTGKNNQ---ILKEKDELKTQLYAALQQIENLRKELNDVLTKRALQEEELHSKEEKLR 204 Query: 164 AYKTYSAD-QLEVAQK----HAAELEV-QVSALDQQLQEAEIHYKNKVAEESEKLALVNT 325 K++ AD +LEV H E E+ + S + Q++ + H + ++AE + A Sbjct: 205 DIKSHQADLELEVKNSLDTIHRLESELKKQSKIQSQMKVEKAHLEEEIAELKKSQA---- 260 Query: 326 QLNKLTQNVSKSAEMEKKVQDLEQ-KLQLAYSKSDEQ-AKDAVVSTRSREFSLDSLTPQN 499 Q+ +K EM++ ++DL + LA ++E+ AK AV+ L LT Q Sbjct: 261 ------QDKAKLLEMQESIKDLSAIRADLANKLAEEERAKKAVLK------DLSDLTAQA 308 Query: 500 KEQD 511 K +D Sbjct: 309 KSRD 312 Score = 39.3 bits (90), Expect = 0.010 Identities = 44/196 (22%), Positives = 86/196 (43%), Gaps = 4/196 (2%) Frame = +2 Query: 8 ALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSAD 187 A+ S+++E + KD+ + L ++E R + N E+Q + D Sbjct: 12 AMASELEEVKRCMERKDKEKAHLAS---QVENLTRELENGEKQ-----------QLQMLD 57 Query: 188 QLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAE 367 +L+ Q H E + D Q+ E H AE++ K A L++L Q+ + E Sbjct: 58 RLKEIQNHFDTCEAERKHADLQISELTRH-----AEDATKQA--ERYLSELQQSEALKEE 110 Query: 368 MEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQN----KEQDLSQAPSTA 535 EK+ +DL+ K Q + + + K + + ++D LT +N KE+D + A Sbjct: 111 AEKRREDLKLKAQESIRQWKLKHKKLERALEKQSETVDELTGKNNQILKEKDELKTQLYA 170 Query: 536 SVNPAQQQLREPSGIM 583 ++ + +E + ++ Sbjct: 171 ALQQIENLRKELNDVL 186 Score = 34.7 bits (78), Expect = 0.25 Identities = 32/146 (21%), Positives = 68/146 (46%), Gaps = 10/146 (6%) Frame = +2 Query: 35 ANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASV-------REIKWDAYKTYSADQL 193 AN + E+++ ++ +L+ +L A ++ EE A++ R++ K ++ Sbjct: 284 ANKLAEEERAKKAVLKDLSDLTAQAKS--RDEETATIITQLKLERDVHQRELKDLTSSLQ 341 Query: 194 EVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAE--ESEKLALVNT-QLNKLTQNVSKSA 364 V KH ++ + ++ EAE H + AE E + +A ++ QL KL + Sbjct: 342 SVKTKHEQNIQELMKHFKKEKSEAENHIRTLKAESLEEKNMAKIHRGQLEKLKSQCDRLT 401 Query: 365 EMEKKVQDLEQKLQLAYSKSDEQAKD 442 E + ++ +KL+L Y +Q ++ Sbjct: 402 EELTQNENENKKLKLKYQCLKDQLEE 427
>RAD50_THEMA (Q9X1X1) Probable DNA double-strand break repair rad50 ATPase| Length = 852 Score = 48.1 bits (113), Expect = 2e-05 Identities = 44/181 (24%), Positives = 80/181 (44%), Gaps = 19/181 (10%) Frame = +2 Query: 20 KMQEHANLVHEK--------DQLEQQLLEVRKELEAAYRTIANQEEQASVRE-------- 151 K++E + + +K Q+E QL E++ E+EA T+ Q E+ + Sbjct: 534 KIEEERHSISQKITAADVQISQIENQLKEIKGEIEAKRETLKEQREEMDQLKSDFFDRLR 593 Query: 152 ---IKWDAYKTYSADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVN 322 I ++ ++ ++++ A+K +E ++ L++ L+E E V+E+ EK V Sbjct: 594 KIGIGFEEFRILVKEEVKDAEKELGVVETEIRLLEESLKELESENVRDVSEDYEK---VR 650 Query: 323 TQLNKLTQNVSKSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNK 502 QL L+Q +S DLE+K + + + T RE L SL + K Sbjct: 651 NQLEALSQEIS----------DLERK--------EGRLNHLIEETLRRERELKSLEKKLK 692 Query: 503 E 505 E Sbjct: 693 E 693
>RAD50_PYRAB (Q9UZC8) DNA double-strand break repair rad50 ATPase| Length = 880 Score = 47.4 bits (111), Expect = 4e-05 Identities = 40/164 (24%), Positives = 78/164 (47%), Gaps = 7/164 (4%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKW-DAYKTYS 181 E K E E +L+ +L + + EL+ A+ +A+ E + +E K D ++ Sbjct: 599 EEFHDKYVEAKKSESELRELKNKLEKEKTELDQAFEMLADVENEIEEKEAKLKDLESKFN 658 Query: 182 ADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKN------KVAEESEKLALVNTQLNKLT 343 ++ E ++ +LE +VS+L +L+E + + K+ EE E+ ++ KL Sbjct: 659 EEEYEEKRERLVKLEREVSSLTARLEELKKSVEQIKATLRKLKEEKEEREKAKLEIKKLE 718 Query: 344 QNVSKSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFS 475 + +SK V+DL +K++ + + EQA + + S FS Sbjct: 719 KALSK-------VEDLRKKIKDYKTLAKEQALNRISEIASEIFS 755
>MYSA_DROME (P05661) Myosin heavy chain, muscle| Length = 1962 Score = 46.6 bits (109), Expect = 6e-05 Identities = 44/188 (23%), Positives = 82/188 (43%) Frame = +2 Query: 2 NEALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYS 181 +E L ++A++ K +LE +L + +L+ N EE+A + DA + Sbjct: 1709 HEQLNEVSAQNASISAAKRKLESELQTLHSDLDELLNEAKNSEEKAKKAMV--DAARL-- 1764 Query: 182 ADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKS 361 AD+L Q HA E AL+QQ++E ++ L + N L Sbjct: 1765 ADELRAEQDHAQTQEKLRKALEQQIKELQVR-------------LDEAEANALKGGKKAI 1811 Query: 362 AEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQAPSTASV 541 ++E++V++LE +L + DA + R E + L+ Q++E + V Sbjct: 1812 QKLEQRVRELENEL----DGEQRRHADAQKNLRKSERRVKELSFQSEEDRKNHERMQDLV 1867 Query: 542 NPAQQQLR 565 + QQ+++ Sbjct: 1868 DKLQQKIK 1875
>MRCKA_RAT (O54874) Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1)| (CDC42-binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) Length = 1732 Score = 46.2 bits (108), Expect = 8e-05 Identities = 53/209 (25%), Positives = 99/209 (47%), Gaps = 25/209 (11%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQQLLE---VRKELEAAYRTIANQEEQASVREIKWDAYKT 175 ++L ++++ V E + LEQQL E VR+EL+ A+R I E+Q KT Sbjct: 490 KSLKEEIEKLRKQVAEVNHLEQQLEEANSVRRELDDAFRQIKAFEKQ----------IKT 539 Query: 176 YSADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVA-----EESEKLALVNTQLNKL 340 ++ E+ K + ++ ++L++A H + K+A E +E+L ++TQ KL Sbjct: 540 LQQEREEL-NKELVQASERLKNQSKELKDA--HCQRKLAMQEFMEINERLTELHTQKQKL 596 Query: 341 TQNVSKSAE----MEKKVQDLEQKLQLAYSKSD-----------EQAKDAVVSTRSREFS 475 ++V E + +K + L Q+L+ A E +KD + +SR +S Sbjct: 597 ARHVRDKEEEVDLVMQKAESLRQELRRAERAKKELEVHTEALIAEASKDRKLREQSRHYS 656 Query: 476 --LDSLTPQNKEQDLSQAPSTASVNPAQQ 556 L++ K++ +S +P S+ Q+ Sbjct: 657 KQLENELEGLKQKQISYSPGICSIEHQQE 685 Score = 37.4 bits (85), Expect = 0.038 Identities = 28/120 (23%), Positives = 56/120 (46%), Gaps = 6/120 (5%) Frame = +2 Query: 59 QLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKHAAELEVQVS 238 ++ ++L E+ + + R + ++EE+ + K ++ + +L A++ ELEV Sbjct: 581 EINERLTELHTQKQKLARHVRDKEEEVDLVMQKAESLR----QELRRAERAKKELEVHTE 636 Query: 239 AL------DQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEMEKKVQDLEQK 400 AL D++L+E HY ++ E E L + ++ E+ K DLE+K Sbjct: 637 ALIAEASKDRKLREQSRHYSKQLENELEGLKQKQISYSPGICSIEHQQEITKLKTDLEKK 696
>LVA_DROME (Q8MSS1) Protein lava lamp| Length = 2779 Score = 46.2 bits (108), Expect = 8e-05 Identities = 51/207 (24%), Positives = 99/207 (47%), Gaps = 20/207 (9%) Frame = +2 Query: 5 EALTSKMQEHANLV--------------HEKDQLEQQLLEVRKELEAAYRTIANQEEQAS 142 + LTS++QE LV H +QL+QQ+ ++ ++L+A + N E + + Sbjct: 1105 QELTSQLQEQQELVKQKEEVEREPIVDNHRVEQLQQQVSKLNEDLKA--KIHLNLENRDA 1162 Query: 143 VREIKWDAYKTYSADQLEVAQKHAAELE---VQVSALDQQLQEAEIHYKNKVAEES---E 304 +R++K +Q ++ Q+ AEL+ + L ++ QEA+ E S E Sbjct: 1163 LRQLKQQI-----QEQEQLIQERDAELQDANLVSKELRRERQEADQEVFQLGQENSRLRE 1217 Query: 305 KLALVNTQLNKLTQNVSKSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDS 484 +++ + +++ L Q V+ E V+DL ++L+ A SK E++K+ + + SL Sbjct: 1218 EISKLQEEIHNLGQRVN---EEPTAVEDLRRQLE-AKSKKFEKSKELIKLRNATIQSLQR 1273 Query: 485 LTPQNKEQDLSQAPSTASVNPAQQQLR 565 Q ++ S+ + A +QLR Sbjct: 1274 ELQQLQQDQDSEVEHVRNARAAHEQLR 1300 Score = 38.5 bits (88), Expect = 0.017 Identities = 35/164 (21%), Positives = 73/164 (44%), Gaps = 5/164 (3%) Frame = +2 Query: 32 HANLVHEKDQLEQ--QLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYS---ADQLE 196 +A HE+ +LE+ ++ +R+E+ R+ A E ++ + ++ S A+ L+ Sbjct: 1291 NARAAHEQLRLEKDAEITALRQEILKLERSRAAGEGDDTITKTSHQLLESQSQQQAESLQ 1350 Query: 197 VAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEMEK 376 VA++ +L VQ++A +Q Y + A +A + T + + + A + Sbjct: 1351 VAERELQQLRVQLTAAQEQHALLAQQYASDKANFEMTIARLETLHEGIQAKLQEDASYIE 1410 Query: 377 KVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQ 508 ++ +LQ + +EQA + + + L Q KEQ Sbjct: 1411 SLEAQNTELQARSAALEEQAASQANQQAASQDKVQILEQQLKEQ 1454 Score = 36.2 bits (82), Expect = 0.085 Identities = 49/206 (23%), Positives = 83/206 (40%), Gaps = 17/206 (8%) Frame = +2 Query: 2 NEALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYS 181 +E + +K+QE A+ + + LE Q E++ A A+Q Q + + K Sbjct: 1395 HEGIQAKLQEDASYI---ESLEAQNTELQARSAALEEQAASQANQQAASQDK-------- 1443 Query: 182 ADQLEVAQKHAAELEVQVSALDQQLQE-------------AEIHYKNKVAEES-EKLALV 319 LE K E E Q DQQLQE ++ AEES ++LA + Sbjct: 1444 VQILEQQLKEQREQEEQKRQQDQQLQERFYELGQREQAQSRQLELLTSEAEESRQQLAGL 1503 Query: 320 NTQLNKLT---QNVSKSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLT 490 T+ L ++ +A+ E++ + +LA + K+A + R R+ L Sbjct: 1504 RTEYESLLAKHSQLTATAQAEREQMSSHSQEELAELRQQLDVKEADLH-RQRQVYDAKLA 1562 Query: 491 PQNKEQDLSQAPSTASVNPAQQQLRE 568 + E D + + V A + RE Sbjct: 1563 AKATELDELECDLNSHVERAAAETRE 1588 Score = 35.0 bits (79), Expect = 0.19 Identities = 42/193 (21%), Positives = 79/193 (40%), Gaps = 21/193 (10%) Frame = +2 Query: 2 NEALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYS 181 +EA + Q A L + +L QL +++ E + +A Q K Sbjct: 357 SEAAHTDAQVSAELAKQLQELTNQLADLQATNEELRQQVAAQA-------------KLQV 403 Query: 182 ADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNV--- 352 D E+ + ELE ++A +LQE K+ +A ++E+LA T+LN L N+ Sbjct: 404 TD--EIVSQRLEELEATIAAQLLELQE----QKSAMAAQNEELAEKTTELNVLNVNLRLL 457 Query: 353 ------------------SKSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSL 478 S+ + K++Q+ Q+L+L ++++ + + E L Sbjct: 458 EEKLAQSSRSKPLFLEDHSEDSAASKQMQEDLQQLKLKLDETNKANIKLKLKCKQAEKKL 517 Query: 479 DSLTPQNKEQDLS 517 Q+ +Q L+ Sbjct: 518 QKFQSQDGQQQLA 530 Score = 32.7 bits (73), Expect = 0.94 Identities = 40/193 (20%), Positives = 85/193 (44%), Gaps = 11/193 (5%) Frame = +2 Query: 23 MQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVA 202 + E+ L + +L+ + +R+EL+ + E +A + + D+ + QL+ Sbjct: 830 LAEYEQLNAQNAELKAVISRLRQELDELRESYP--ETEAPLAIVGSDSQREDEILQLQSQ 887 Query: 203 QKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEMEKKV 382 + A L+ + QQ++E K E+E+L LV Q ++TQ +S + ++ + Sbjct: 888 LEDARSLQAEQR---QQIEEQVDQIKELRQTEAEQLQLVARQSAEITQLQLQSEQFDQLL 944 Query: 383 --QDLEQKLQLAYSKSDEQAKDAVVSTRSREFS-LDSLTPQNKEQDLSQAPST------- 532 +++ + QL + +A + E S L +L + K+Q + + Sbjct: 945 NSKEMSHEKQLEQQTRIRRELEARAESLEGELSILQTLVAEQKQQLIESVSESEHALNLK 1004 Query: 533 -ASVNPAQQQLRE 568 + AQ++LRE Sbjct: 1005 MLELQSAQEELRE 1017 Score = 32.3 bits (72), Expect = 1.2 Identities = 44/191 (23%), Positives = 80/191 (41%), Gaps = 2/191 (1%) Frame = +2 Query: 2 NEALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYS 181 +E + ++ + +VH K ++E+ + E + E NQE Q ++K Sbjct: 2293 DEQMAQLQEKESEIVHLKQRIEELMREDQTEKLVFEILTKNQELQLLRMQVKQLEEDKED 2352 Query: 182 ADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKS 361 K E ++ +L QQLQ+ E+S+ + +L L +V S Sbjct: 2353 QQVSAAPPKDDGETVEKLKSLCQQLQQ----------EKSD----MEEELRVLNNHVLSS 2398 Query: 362 AEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQD--LSQAPSTA 535 E+E +++ + LQL K+ ++ R SL+ L QN Q+ Q P + Sbjct: 2399 LELEDRMK--QTLLQL-------DTKNIEITELRR--SLEILQSQNLGQNSAAEQIPDLS 2447 Query: 536 SVNPAQQQLRE 568 ++N +QL E Sbjct: 2448 AINQQWEQLVE 2458
>MRCKG_HUMAN (Q6DT37) Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1)| (CDC42-binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma Length = 1551 Score = 45.8 bits (107), Expect = 1e-04 Identities = 44/177 (24%), Positives = 86/177 (48%), Gaps = 13/177 (7%) Frame = +2 Query: 29 EHANLVHEKDQLEQQLLEVRKELEAAYRTIAN----QEE------QASVREIKWDAYKTY 178 + ++L E D+L ++L E R L+A + + QEE +A RE + Sbjct: 483 QDSDLRQELDRLHRELAEGRAGLQAQEQELCRAQGQQEELLQRLQEAQEREAATASQTRA 542 Query: 179 SADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESE-KLALVNTQLNKL--TQN 349 + QLE A+ ELE QVS+L +Q+ + + ++ ++ E S+ K ++ N + + Sbjct: 543 LSSQLEEARAAQRELEAQVSSLSRQVTQLQGQWEQRLEESSQAKTIHTASETNGMGPPEG 602 Query: 350 VSKSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQ 520 + A++ K+V L ++L+ A+S ++A+ + L S + E +L+Q Sbjct: 603 GPQEAQLRKEVAALREQLEQAHSHRRSGKEEALCQLQEENRRL-SREQERLEAELAQ 658
>MYSP_SARSC (Q9BMM8) Paramyosin| Length = 876 Score = 45.8 bits (107), Expect = 1e-04 Identities = 43/194 (22%), Positives = 92/194 (47%), Gaps = 14/194 (7%) Frame = +2 Query: 17 SKMQEHANLVHEKDQLEQQLLEVRKELEAAYR---TIANQEE------QASVREIKWDAY 169 S++ + +HE++ ++L R+EL AAY+ T+ QEE A + +++ D Y Sbjct: 438 SQLNDAHRRIHEQEIEIKRLENEREELSAAYKEAETLRKQEEAKNQRLTAELAQVRHD-Y 496 Query: 170 KTYSADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQN 349 + A + E + + ++++ L+ +L EAE K ++A +K T+L +L+ + Sbjct: 497 EKRLAQKEEEIEALRKQYQIEIEQLNMRLAEAEAKLKTEIARLKKKYQAQITEL-ELSLD 555 Query: 350 VSKSAEMEKKVQDLEQKLQLA-----YSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDL 514 + A ++ + +Q LQ+ Y + Q + AV + +L + +EQ + Sbjct: 556 AANKANIDLQKTIKKQALQITELQAHYDEVHRQLQQAVDQLGVTQRRCQALQAELEEQRI 615 Query: 515 SQAPSTASVNPAQQ 556 + + + A+Q Sbjct: 616 ALEQANRAKRQAEQ 629 Score = 36.2 bits (82), Expect = 0.085 Identities = 25/77 (32%), Positives = 41/77 (53%) Frame = +2 Query: 203 QKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEMEKKV 382 ++ AEL++QV +L ++L+EAE V E ++K +L KL ++V E E+ Sbjct: 57 EREKAELQIQVMSLSERLEEAE-GSSESVVEMNKKRDSELAKLRKLLEDV--HLESEETA 113 Query: 383 QDLEQKLQLAYSKSDEQ 433 L QK Q A + +Q Sbjct: 114 HHLRQKHQAAIQEMQDQ 130 Score = 32.7 bits (73), Expect = 0.94 Identities = 42/165 (25%), Positives = 73/165 (44%), Gaps = 10/165 (6%) Frame = +2 Query: 2 NEALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIAN--------QEEQASVREIK 157 ++ L S+ + + EK +L+ Q++ + + LE A + + E A +R++ Sbjct: 43 SDDLESEREMRQRIEREKAELQIQVMSLSERLEEAEGSSESVVEMNKKRDSELAKLRKLL 102 Query: 158 WDAYKTYSADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKL-ALVNTQLN 334 D + + QKH A ++ LD Q+Q+A KNK +E +K A V L Sbjct: 103 EDVHLESEETAHHLRQKHQAAIQEMQDQLD-QVQKA----KNKSDKEKQKFQAEVFELLA 157 Query: 335 KL-TQNVSKSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSR 466 +L T N K M K V+ LE + K +E + + T + Sbjct: 158 QLETANKEKLTAM-KTVEKLEYTVHELNIKIEEINRTVIELTSQK 201 Score = 32.0 bits (71), Expect = 1.6 Identities = 37/158 (23%), Positives = 61/158 (38%), Gaps = 12/158 (7%) Frame = +2 Query: 2 NEALTSKMQEHA----NLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAY 169 N L ++ EH N H K QL QQL + + LE R A+ E Sbjct: 208 NTELIKEVHEHKMQLDNANHLKQQLAQQLEDTKHRLEEEERKRASLEN------------ 255 Query: 170 KTYSADQLEVAQKHAAELEVQVSALDQQL---QEAEIHYKNKVAEESEKLALVNTQLNKL 340 HA LEV++ +L QL EA + + ++ + + A ++ Sbjct: 256 -------------HAHTLEVELESLKVQLDEESEARLELERQLTKANGDAASWKSKYEAE 302 Query: 341 TQNVSKSAE-----MEKKVQDLEQKLQLAYSKSDEQAK 439 Q + E M +K+ + E++L+ +K AK Sbjct: 303 LQAHADEVEELRRKMAQKISEYEEQLEALLNKCSSLAK 340
>SMC2_XENLA (P50533) Structural maintenance of chromosome 2| (Chromosome-associated protein E) (Chromosome assembly protein XCAP-E) Length = 1203 Score = 45.4 bits (106), Expect = 1e-04 Identities = 37/149 (24%), Positives = 68/149 (45%), Gaps = 7/149 (4%) Frame = +2 Query: 44 VHEKDQLEQQLLEVRKELEAAYRTIANQEEQASV---REIKWDAYKTYSADQ-LEVAQKH 211 + E ++ + EV+K+ E ++ + ++ + A RE+K K +A + + + K Sbjct: 753 IEESEETLKNTKEVQKKAEEKFKVLEHKMKNAEAERERELKEAQQKLDTAKKKADASNKK 812 Query: 212 AAELEVQVSALDQQLQEA---EIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEMEKKV 382 E + +V AL +L+E + YK ++ E + Q + + VSK+ E KK Sbjct: 813 MKEKQQEVDALVLELEELKREQTTYKQQIETVDEAMKAYQEQADSMASEVSKNKEAVKKA 872 Query: 383 QDLEQKLQLAYSKSDEQAKDAVVSTRSRE 469 QD +LA K D + T+S E Sbjct: 873 QD-----ELAKQKEIIMGHDKEIKTKSSE 896 Score = 43.9 bits (102), Expect = 4e-04 Identities = 50/205 (24%), Positives = 96/205 (46%), Gaps = 10/205 (4%) Frame = +2 Query: 2 NEALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYS 181 N ++ ++QE ++ E E +L EV KEL T+ N E+ + +W+ K+ Sbjct: 672 NASVLVRLQELKDVQDELKAKETELQEVEKEL----MTLKNTVERYRQLKQQWE-MKSEE 726 Query: 182 AD--QLEVAQKHAAELEVQVSALDQQLQEAEIHYKN-----KVAEESEKLALVNTQLNKL 340 A+ Q ++ Q + + ++ +L Q ++E+E KN K AEE K+ L Sbjct: 727 AELLQTKLQQSSYHKQQEELDSLKQTIEESEETLKNTKEVQKKAEEKFKV------LEHK 780 Query: 341 TQNVSKSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLT---PQNKEQD 511 +N AE E+++++ +QKL A K+D K + ++ +D+L + K + Sbjct: 781 MKNA--EAERERELKEAQQKLDTAKKKADASNK----KMKEKQQEVDALVLELEELKREQ 834 Query: 512 LSQAPSTASVNPAQQQLREPSGIMA 586 + +V+ A + +E + MA Sbjct: 835 TTYKQQIETVDEAMKAYQEQADSMA 859
>MYH11_CHICK (P10587) Myosin-11 (Myosin heavy chain, gizzard smooth muscle)| Length = 1978 Score = 45.4 bits (106), Expect = 1e-04 Identities = 45/201 (22%), Positives = 78/201 (38%), Gaps = 8/201 (3%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYK---- 172 E L S+ +K L ++L ++ ELE T A Q+E + RE + K Sbjct: 1130 EDLESEKAARNKAEKQKRDLSEELEALKTELEDTLDTTATQQELRAKREQEVTVLKRALE 1189 Query: 173 ----TYSADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKL 340 T+ A E+ QKH +E L+Q + K K E + L N ++ L Sbjct: 1190 EETRTHEAQVQEMRQKHTQAVEELTEQLEQFKRAKANLDKTKQTLEKDNADLAN-EIRSL 1248 Query: 341 TQNVSKSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQ 520 +Q +KK++ Q LQ YS + + + ++++T E + Sbjct: 1249 SQAKQDVEHKKKKLEVQLQDLQSKYSDGERVRTELNEKVHKLQIEVENVTSLLNEAESKN 1308 Query: 521 APSTASVNPAQQQLREPSGIM 583 T V QL++ ++ Sbjct: 1309 IKLTKDVATLGSQLQDTQELL 1329 Score = 39.3 bits (90), Expect = 0.010 Identities = 38/177 (21%), Positives = 76/177 (42%), Gaps = 7/177 (3%) Frame = +2 Query: 11 LTSKMQEHANLVHEKDQL-------EQQLLEVRKELEAAYRTIANQEEQASVREIKWDAY 169 L K+Q L E +++ +Q+L E+ E+EA + +Q + K Sbjct: 897 LQEKLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARIEEEEERSQQLQAEKKKMQQQ 956 Query: 170 KTYSADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQN 349 +QLE + A Q+LQ ++ K+ + + + ++ Q NKLT+ Sbjct: 957 MLDLEEQLE-----------EEEAARQKLQLEKVTADGKIKKMEDDILIMEDQNNKLTK- 1004 Query: 350 VSKSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQ 520 + +E++V DL L ++ +E+AK+ E + L + K+++ S+ Sbjct: 1005 --ERKLLEERVSDLTTNL----AEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSR 1055 Score = 37.7 bits (86), Expect = 0.029 Identities = 36/195 (18%), Positives = 80/195 (41%), Gaps = 7/195 (3%) Frame = +2 Query: 5 EALTSKMQEHANLVHEK-DQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYS 181 E +K+ + L+ E+ L L E ++ + + E S E++ + Sbjct: 996 EDQNNKLTKERKLLEERVSDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSR 1055 Query: 182 ADQLEVAQK---HAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNV 352 + ++ +K +++L Q++ L Q+ E + K E LA + + ++ + Sbjct: 1056 QELEKIKRKLEGESSDLHEQIAELQAQIAELKAQLAKKEEELQAALARLEDETSQKNNAL 1115 Query: 353 SKSAEMEKKVQDLEQKLQ---LAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQA 523 K E+E + DL++ L+ A +K+++Q +D + + L+ Q +A Sbjct: 1116 KKIRELESHISDLQEDLESEKAARNKAEKQKRDLSEELEALKTELEDTLDTTATQQELRA 1175 Query: 524 PSTASVNPAQQQLRE 568 V ++ L E Sbjct: 1176 KREQEVTVLKRALEE 1190 Score = 35.0 bits (79), Expect = 0.19 Identities = 38/155 (24%), Positives = 72/155 (46%), Gaps = 9/155 (5%) Frame = +2 Query: 2 NEALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYS 181 N+ L ++M++ LV KD + + + ELE + RT+ Q E+ + + + Sbjct: 1511 NKMLKAEMED---LVSSKDDVGKNV----HELEKSKRTLEQQVEEMKTQLEELE------ 1557 Query: 182 ADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALV-----NTQLNKLTQ 346 D+L+ A+ LEV + A+ Q E ++ +++ EE + L T+L + Sbjct: 1558 -DELQAAEDAKLRLEVNMQAMKSQF-ERDLQARDEQNEEKRRQLLKQLHEHETELEDERK 1615 Query: 347 NVSKSAEMEKK----VQDLEQKLQLAYSKSDEQAK 439 + +A +KK V+DLE ++ A +E K Sbjct: 1616 QRALAAAAKKKLEVDVKDLESQVDSANKAREEAIK 1650
>ROCK2_BOVIN (Q28021) Rho-associated protein kinase 2 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 2) (p164 ROCK-2) Length = 1388 Score = 45.1 bits (105), Expect = 2e-04 Identities = 45/186 (24%), Positives = 88/186 (47%), Gaps = 7/186 (3%) Frame = +2 Query: 26 QEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQ 205 QE+ +L+ K LE+Q E+RKE + A + ++Q + YKT Q+ + Sbjct: 829 QENNHLLEMKMSLEKQNAELRKERQDADGQMKELQDQLEAEQYFSTLYKT----QVRELK 884 Query: 206 KHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSK----SAEME 373 + E L Q+ QE + ++ +A + E + L +L +++++ E E Sbjct: 885 EECEEKTKLCKELQQKKQELQ-DERDSLAAQLE-ITLTKADSEQLARSIAEEQYSDLEKE 942 Query: 374 KKVQDLEQKLQLAYSKSDEQAKDAVVST---RSREFSLDSLTPQNKEQDLSQAPSTASVN 544 K +++LE K +A K + KDA +++ +R + D N++++L+ + Sbjct: 943 KIMKELEIKEMMARHKQELTEKDATIASLEETNRTLTSDVANLANEKEELNN-----KLK 997 Query: 545 PAQQQL 562 AQ+QL Sbjct: 998 EAQEQL 1003
>MFP1_LYCES (P93203) MAR binding filament-like protein 1| Length = 697 Score = 44.7 bits (104), Expect = 2e-04 Identities = 48/193 (24%), Positives = 79/193 (40%), Gaps = 22/193 (11%) Frame = +2 Query: 5 EALTSKMQEHAN-LVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYS 181 E++ +K+++ + V K Q E +LL R++ R +E QA V ++K S Sbjct: 140 ESMKNKLKDKEDAFVSMKKQFESELLSEREDRNKLIRR-EGEERQALVNQLKSAKTTVIS 198 Query: 182 ADQ-LEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLT----- 343 Q L+ +K A +L+ ++ L L + K E EKL L+ K+T Sbjct: 199 LGQELQNEKKLAEDLKFEIKGLQNDLMNTKEDKKKLQEELKEKLDLIQVLEEKITLLTTE 258 Query: 344 ---------QNVSKSAEMEKKVQDLEQKLQ------LAYSKSDEQAKDAVVSTRSREFSL 478 N SK AE E +V L Q + + ++ KD + R RE L Sbjct: 259 IKDKEVSLRSNTSKLAEKESEVNSLSDMYQQSQDQLMNLTSEIKELKDE-IQKRERELEL 317 Query: 479 DSLTPQNKEQDLS 517 ++ N L+ Sbjct: 318 KCVSEDNLNVQLN 330 Score = 29.6 bits (65), Expect = 7.9 Identities = 37/162 (22%), Positives = 66/162 (40%), Gaps = 25/162 (15%) Frame = +2 Query: 2 NEALTSKMQEHANLVHEKDQLEQQLLEV-------RKELEAAYRTIANQEEQASVREIKW 160 NE + + E + +D L+ +L+ V R EL+ + EE+ E + Sbjct: 501 NEEMHTMSDELVAVSENRDSLQTELVNVYKKREHTRNELKQEKTIVRTLEEELKFLESQI 560 Query: 161 DAYKTYS---ADQLEVAQKHAAELEVQVSALDQQLQ-----------EAEIHYKNKVAEE 298 K D+LE A + E+ V AL ++L+ E E+H + V+E+ Sbjct: 561 TREKELRKSLEDELEKATESLDEINRNVLALAEELELATSRNSSLEDEREVH-RQSVSEQ 619 Query: 299 SEKLALVNTQL---NKLTQNVSKSAE-MEKKVQDLEQKLQLA 412 + L + L + K E +EK+ + LE ++ A Sbjct: 620 KQISQEAQENLEDAHSLVMKLGKERESLEKRAKKLEDEMAAA 661
>MYSN_DROME (Q99323) Myosin heavy chain, non-muscle (Zipper protein) (Myosin II)| (Non-muscle MHC) Length = 2057 Score = 44.7 bits (104), Expect = 2e-04 Identities = 34/149 (22%), Positives = 73/149 (48%), Gaps = 1/149 (0%) Frame = +2 Query: 5 EALTSKMQEHAN-LVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYS 181 E S++QE L E + + QL E + AA ++ +N E Q + + + + Sbjct: 1356 ERARSELQEKCTKLQQEAENITNQLEEAELKASAAVKSASNMESQLTEAQ---QLLEEET 1412 Query: 182 ADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKS 361 +L ++ K ++E + AL +QL+E + +N KLA V TQ+ ++ + + Sbjct: 1413 RQKLGLSSK-LRQIESEKEALQEQLEEDDEAKRNY----ERKLAEVTTQMQEIKKKAEED 1467 Query: 362 AEMEKKVQDLEQKLQLAYSKSDEQAKDAV 448 A++ K++++ +++L + Q K+ + Sbjct: 1468 ADLAKELEEGKKRLNKDIEALERQVKELI 1496
>MYSP_BLOTA (Q8MUF6) Paramyosin (Allergen Blo t 11)| Length = 875 Score = 44.7 bits (104), Expect = 2e-04 Identities = 45/198 (22%), Positives = 92/198 (46%), Gaps = 14/198 (7%) Frame = +2 Query: 17 SKMQEHANLVHEKDQLEQQLLEVRKELEAAYR---TIANQEE------QASVREIKWDAY 169 S++ + +HE++ ++L R+EL AAY+ T+ QEE A + + + D Y Sbjct: 438 SQLNDAHRRIHEQEIEIKRLENEREELAAAYKEAETLRKQEEAKNQRLTAELAQTRHD-Y 496 Query: 170 KTYSADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQN 349 + A + E + + ++++ L+ +L EAE K +VA +K T+L +L+ + Sbjct: 497 EKRLAQKEEEIEALRKQYQIEIEQLNMRLAEAEAKLKTEVARLKKKYQAQITEL-ELSLD 555 Query: 350 VSKSAEMEKKVQDLEQKLQLA-----YSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDL 514 + A ++ + +Q LQ+ Y + Q + AV + +LT + +E + Sbjct: 556 AANKANIDLQKTIKKQALQITGLQAHYDEVHRQLQQAVDQLGVTQRRCQALTAELEEMRV 615 Query: 515 SQAPSTASVNPAQQQLRE 568 + + + A+Q E Sbjct: 616 NLEQALRAKRAAEQMHEE 633 Score = 34.3 bits (77), Expect = 0.32 Identities = 41/177 (23%), Positives = 74/177 (41%), Gaps = 9/177 (5%) Frame = +2 Query: 2 NEALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIAN--------QEEQASVREIK 157 +E L S+ + + EK + QL+ + + LE + + E A +R++ Sbjct: 43 SEDLESERELRQRVEREKSDITVQLMNLTERLEETEGSSESVTEMNKKRDSELAKLRKLL 102 Query: 158 WDAYKTYSADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNK 337 D + + QKH A ++ LD Q+Q+A KNK +E +K +L Sbjct: 103 EDVHMESEETAHHLRQKHQAAIQEMQDQLD-QVQKA----KNKSDKEKQKFQAEVFELLA 157 Query: 338 LTQNVSKSAEM-EKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKE 505 + +K + +K V+ LE + K +E + V T R+ L+ +N E Sbjct: 158 QVETANKDKLVAQKTVEKLEYTVHELNIKIEEINRTVVEVTAHRQ----RLSQENSE 210
>CCD46_HUMAN (Q8N8E3) Coiled-coil domain-containing protein 46| Length = 955 Score = 44.3 bits (103), Expect = 3e-04 Identities = 44/188 (23%), Positives = 82/188 (43%), Gaps = 20/188 (10%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQ-------QLLEVRKELEAAYRT----IANQEEQASVRE 151 EA S +Q L+ EK +LE+ +L EV+ ++ + + E+ + + Sbjct: 423 EAENSNLQRQ-KLIQEKAELERCYQITCSELQEVKARRNTLHKEKDHLVNDYEQNMKLLQ 481 Query: 152 IKWDA----YKTYSADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALV 319 K+DA K A A ELE V L QQLQE+E+ K ++ ++ K + Sbjct: 482 TKYDADINLLKQEHALSASKASSMIEELEQNVCQLKQQLQESELQRKQQLRDQENKFQME 541 Query: 320 NTQLNKLTQNVSK--SAEMEKKVQDLEQKL---QLAYSKSDEQAKDAVVSTRSREFSLDS 484 + L + + + +E++K +D ++K+ + A + +EQ R + D+ Sbjct: 542 KSHLKHIYEKKAHDLQSELDKGKEDTQKKIHKFEEALKEKEEQLTRVTEVQRLQAQQADA 601 Query: 485 LTPQNKEQ 508 + K Q Sbjct: 602 ALEEFKRQ 609
>SDCG8_HUMAN (Q86SQ7) Serologically defined colon cancer antigen 8 (Centrosomal| colon cancer autoantigen protein) (hCCCAP) (Antigen NY-CO-8) Length = 713 Score = 44.3 bits (103), Expect = 3e-04 Identities = 42/181 (23%), Positives = 75/181 (41%), Gaps = 24/181 (13%) Frame = +2 Query: 50 EKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKHAAELEV 229 EKD +++++ + R+ + + ++ Q + K K + +QLE Q A E+ Sbjct: 389 EKDMMKKEITKEREYMGSKMLILSQNIAQLEAQVEKVTKEKISAINQLEEIQSQLASREM 448 Query: 230 QVSA----LDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSK-SAEMEKKVQDLE 394 V+ + QL + + E E A N L Q + K E+++ Q LE Sbjct: 449 DVTKVCGEMRYQLNKTNMEKDEAEKEHREFRAKTNRDLEIKDQEIEKLRIELDESKQHLE 508 Query: 395 QKLQLAYSKSDE-------------------QAKDAVVSTRSREFSLDSLTPQNKEQDLS 517 Q+ Q A +E Q KD++ + S+E +L Q +EQ+L+ Sbjct: 509 QEQQKAALAREECLRLTELLGESEHQLHLTRQEKDSIQQSFSKEAKAQALQAQQREQELT 568 Query: 518 Q 520 Q Sbjct: 569 Q 569
>MD1L1_MOUSE (Q9WTX8) Mitotic spindle assembly checkpoint protein MAD1 (Mitotic| arrest deficient-like protein 1) (MAD1-like 1) Length = 717 Score = 43.9 bits (102), Expect = 4e-04 Identities = 45/147 (30%), Positives = 72/147 (48%), Gaps = 3/147 (2%) Frame = +2 Query: 20 KMQEHANLVHEK--DQLEQQLLEVRKELEAAYRTIANQEEQ-ASVREIKWDAYKTYSADQ 190 ++QE EK +QLE+ L ++ L+A + + QE+ AS RE+ S Q Sbjct: 112 QLQECEATAEEKMREQLERHRL-CKQNLDAVSQQLREQEDSLASAREMISSLKGRVSELQ 170 Query: 191 LEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEM 370 L A + +VQV L+ + QE K ++ + K N ++ +L + + AE Sbjct: 171 LS-----AMDQKVQVKRLESEKQEL----KEQLELQQRKWQEANQKIQELQASQDERAEH 221 Query: 371 EKKVQDLEQKLQLAYSKSDEQAKDAVV 451 E+K++DLEQKL L Q +DA V Sbjct: 222 EQKIKDLEQKLCL-------QEQDAAV 241
>CL190_DROME (Q9VJE5) Restin homolog (Cytoplasmic linker protein 190)| (Microtubule-binding protein 190) (d-CLIP-190) Length = 1690 Score = 43.9 bits (102), Expect = 4e-04 Identities = 48/201 (23%), Positives = 95/201 (47%), Gaps = 23/201 (11%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSA 184 E +T + +E + + E+ + EQ+L E K L T+ Q E S K +A + +S Sbjct: 495 EKMTIQQKEVESRIAEQLEEEQRLRENVKYLNEQIATL--QSELVS----KDEALEKFSL 548 Query: 185 DQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKL-------- 340 + + + ELE+ ++Q QEA+ + K+AE+S ++ ++++L L Sbjct: 549 SECGI-ENLRRELELLKEENEKQAQEAQAEFTRKLAEKSVEVLRLSSELQNLKATSDSLE 607 Query: 341 TQNVSKSAEME----------KKVQDLEQKL-----QLAYSKSDEQAKDAVVSTRSREFS 475 ++ V+K+ E E +++++L Q+L QL K+D A D ++ + Sbjct: 608 SERVNKTDECEILQTEVRMRDEQIRELNQQLDEVTTQLNVQKADSSALDDMLRLQKEGTE 667 Query: 476 LDSLTPQNKEQDLSQAPSTAS 538 S + E++L Q+ A+ Sbjct: 668 EKSTLLEKTEKELVQSKEQAA 688 Score = 43.5 bits (101), Expect = 5e-04 Identities = 42/187 (22%), Positives = 75/187 (40%) Frame = +2 Query: 8 ALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSAD 187 AL +E ++ EK+Q QQL E E+A + + Q EQ + +A Sbjct: 798 ALEELKKEKETIIKEKEQELQQLQSKSAESESALKVVQVQLEQ----------LQQQAAA 847 Query: 188 QLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAE 367 E K A+L ++S L Q +E + K+ + K + L + KS Sbjct: 848 SGEEGSKTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSGH 907 Query: 368 MEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQAPSTASVNP 547 + +++ L+ ++ + D T+ E + +L NKE A S A + Sbjct: 908 LLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEKVNKE----YAESRAEASD 963 Query: 548 AQQQLRE 568 Q +++E Sbjct: 964 LQDKVKE 970 Score = 41.6 bits (96), Expect = 0.002 Identities = 47/197 (23%), Positives = 86/197 (43%), Gaps = 6/197 (3%) Frame = +2 Query: 5 EALTSKMQEHA--NLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTY 178 E L +M E+A + EK+ +EQQL + ELE + E + ++EIK A T Sbjct: 711 EKLVREMTENAINQIQLEKESIEQQLALKQNELEDFQK--KQSESEVHLQEIK--AQNTQ 766 Query: 179 SADQLEVAQKHAAELEVQVSALDQQLQEAEI-HYKNKVAEE---SEKLALVNTQLNKLTQ 346 +L E + L QQL++ + H K + A E EK ++ + +L Q Sbjct: 767 KDFEL-------VESGESLKKLQQQLEQKTLGHEKLQAALEELKKEKETIIKEKEQELQQ 819 Query: 347 NVSKSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQAP 526 SKSAE E ++ ++ +L+ ++ ++ + + L Q +E Sbjct: 820 LQSKSAESESALKVVQVQLEQLQQQAAASGEEGSKTVAKLHDEISQLKSQAEETQSELKS 879 Query: 527 STASVNPAQQQLREPSG 577 + +++ +QL +G Sbjct: 880 TQSNLEAKSKQLEAANG 896 Score = 32.7 bits (73), Expect = 0.94 Identities = 38/161 (23%), Positives = 67/161 (41%), Gaps = 13/161 (8%) Frame = +2 Query: 2 NEALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKW-DAYKTY 178 N AL +E+A E L+ ++ E+ L A + + + K+ D T Sbjct: 944 NAALEKVNKEYAESRAEASDLQDKVKEITDTLHAELQAERSSSSALHTKLSKFSDEIATG 1003 Query: 179 SADQLEVAQKHAAEL---EVQVSALDQQLQE---------AEIHYKNKVAEESEKLALVN 322 + A + E+ E ++ L QQLQ+ AE K K EES K L Sbjct: 1004 HKELTSKADAWSQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKEKSFEESIK-NLQE 1062 Query: 323 TQLNKLTQNVSKSAEMEKKVQDLEQKLQLAYSKSDEQAKDA 445 T+N+ S + ++DL+++L++ ++ + K A Sbjct: 1063 EVTKAKTENLELSTGTQTTIKDLQERLEITNAELQHKEKMA 1103 Score = 31.2 bits (69), Expect = 2.7 Identities = 38/177 (21%), Positives = 78/177 (44%), Gaps = 9/177 (5%) Frame = +2 Query: 80 EVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKHAAELEVQVSALDQQLQ 259 ++++ LE + ++E+ AS K KT + ++VA + + ++S + + LQ Sbjct: 1084 DLQERLEITNAELQHKEKMASEDAQKIADLKTL-VEAIQVANANISATNAELSTVLEVLQ 1142 Query: 260 EAEIHYKNKVAEESEKLALVNTQL---------NKLTQNVSKSAEMEKKVQDLEQKLQLA 412 AE N + E E A +N++ +L + + E +KK ++LE+KL+ A Sbjct: 1143 -AEKSETNHIFELFEMEADMNSERLIEKVTGIKEELKETHLQLDERQKKFEELEEKLKQA 1201 Query: 413 YSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQAPSTASVNPAQQQLREPSGIM 583 + +++ S L + +E S V ++++RE S I+ Sbjct: 1202 QQSEQKLQQESQTSKE----KLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSII 1254
>RRBP1_MOUSE (Q99PL5) Ribosome-binding protein 1 (Ribosome receptor protein)| (mRRp) Length = 1605 Score = 43.9 bits (102), Expect = 4e-04 Identities = 52/200 (26%), Positives = 88/200 (44%), Gaps = 15/200 (7%) Frame = +2 Query: 14 TSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQL 193 TS+++ N E +L Q+L +V KEL +E+Q E K Sbjct: 1016 TSQVESKQNT--ELAKLRQELSKVNKELVEKSEASRQEEQQRKALEAK------------ 1061 Query: 194 EVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEME 373 AA E QV L +E+E + ++ E + +L T L + K+ E + Sbjct: 1062 ------AATFEKQVLQLQASHKESEEALQKRLEEVTRELCRAQTSHANLRADAEKAQEQQ 1115 Query: 374 KKVQDLEQKLQLA----YSKSDE-----------QAKDAVVSTRSREFSLDSLTPQNKEQ 508 ++V +L KLQ + SK +E +A+++ ++ R R S+++L + Q Sbjct: 1116 QRVAELHSKLQSSEVEVKSKCEELSSLHGQLKEARAENSQLTERIR--SIEALLEAGQAQ 1173 Query: 509 DLSQAPSTASVNPAQQQLRE 568 D +QA S A N Q +L+E Sbjct: 1174 D-TQA-SHAEANQQQTRLKE 1191
>MYH8_MOUSE (P13542) Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal)| (MyHC-perinatal) Length = 1937 Score = 43.9 bits (102), Expect = 4e-04 Identities = 47/207 (22%), Positives = 90/207 (43%), Gaps = 19/207 (9%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKW-------- 160 E + ++ A ++ L ++L E+ + LE A + Q E RE ++ Sbjct: 1123 EEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVEMNKKRETEFQKLRRDLE 1182 Query: 161 DAYKTYSADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKL 340 +A + A + +KHA V+ L +Q+ + K K+ +E +L + L+ Sbjct: 1183 EATLQHEATAAALRKKHADS----VAELGEQIDNLQ-RVKQKLEKEKSELKMEIDDLSSN 1237 Query: 341 TQNVSKS-AEMEKKVQDLEQKLQLAYSKSDEQ--------AKDAVVSTRSREFS--LDSL 487 + ++K+ +EK + LE ++ SK +EQ A+ A + T + E+S LD Sbjct: 1238 AEAIAKAKGNLEKMCRTLEDQVSELKSKEEEQQRLINELTAQRARLQTEAGEYSRQLDEK 1297 Query: 488 TPQNKEQDLSQAPSTASVNPAQQQLRE 568 + S+ ST + ++QL E Sbjct: 1298 DALVSQLSRSKQASTQQIEELKRQLEE 1324 Score = 41.6 bits (96), Expect = 0.002 Identities = 44/196 (22%), Positives = 90/196 (45%), Gaps = 10/196 (5%) Frame = +2 Query: 11 LTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQ 190 L ++Q A+ + + ++ +QL++ + +LEA + + + E + A K D+ Sbjct: 890 LQLQVQSEADSLADAEERCEQLIKNKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDE 949 Query: 191 LEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEM 370 +K +LE+ ++ ++++ E NKV +E++A ++ + KLT+ E Sbjct: 950 CSELKKDIDDLELTLAKVEKEKHATE----NKVKNLTEEMAGLDENIAKLTKEKKALQEA 1005 Query: 371 EKKV-------QDLEQKLQLAYSKSDEQAKDAVVS-TRSREFSLDSLTPQNK-EQDLSQA 523 ++ +D L A +K ++Q D S + ++ +D + K E DL A Sbjct: 1006 HQQTLDDLQAEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLA 1065 Query: 524 -PSTASVNPAQQQLRE 568 ST + +QQL E Sbjct: 1066 QESTMDIENDKQQLDE 1081 Score = 35.8 bits (81), Expect = 0.11 Identities = 43/212 (20%), Positives = 88/212 (41%), Gaps = 32/212 (15%) Frame = +2 Query: 29 EHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQK 208 ++ +L++ K +LE + +++ E+E + N EE+A ++ DA A++L+ Q Sbjct: 1722 QNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKA--KKAITDA--AMMAEELKKEQD 1777 Query: 209 HAAELE-----------------------------VQVSALDQQLQEAEIHYKNKV---A 292 +A LE Q+ L+ +++E E +N+ A Sbjct: 1778 TSAHLERMKKNMEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNA 1837 Query: 293 EESEKLALVNTQLNKLTQNVSKSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREF 472 E + L ++ +LT + + ++QDL KLQ QA++A + + Sbjct: 1838 EAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLA 1897 Query: 473 SLDSLTPQNKEQDLSQAPSTASVNPAQQQLRE 568 L + +E + + + VN + + RE Sbjct: 1898 KFRKLQHELEEAEERADIAESQVNKLRVKSRE 1929
>MYH3_HUMAN (P11055) Myosin heavy chain, fast skeletal muscle, embryonic (Muscle| embryonic myosin heavy chain) (SMHCE) Length = 1940 Score = 43.9 bits (102), Expect = 4e-04 Identities = 50/217 (23%), Positives = 91/217 (41%), Gaps = 33/217 (15%) Frame = +2 Query: 2 NEALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYS 181 NE + ++ +L+H K +LE L++++ E+E A R N EE+A ++ DA Sbjct: 1711 NERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKA--KKAITDA--AMM 1766 Query: 182 ADQLEVAQKHAAELE-----------------------------VQVSALDQQLQEAEIH 274 A++L+ Q +A LE Q+ L+ +++E E Sbjct: 1767 AEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEFE 1826 Query: 275 YKNKVAEESEKLALVNTQLNKLTQNVSKSAEMEKKV---QDLEQKLQLAYSKSDEQAKDA 445 + + + +E + + ++ + +S E K V QDL KLQ+ QA++A Sbjct: 1827 LEGEQKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEEA 1886 Query: 446 VVSTRSREFSLDSLTPQNKEQ-DLSQAPSTASVNPAQ 553 + LT K Q +L +A A + +Q Sbjct: 1887 DEQANAH------LTKFRKAQHELEEAEERADIAESQ 1917 Score = 31.6 bits (70), Expect = 2.1 Identities = 50/217 (23%), Positives = 89/217 (41%), Gaps = 9/217 (4%) Frame = +2 Query: 11 LTSKMQEHANLVHEKD----QLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTY 178 LT E + EKD QL++ + +++A +A + K + Sbjct: 1566 LTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNE 1625 Query: 179 SADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEE---SEKLALVNTQLNKLTQN 349 QL A + AAE + ++ QL++ ++H + + + E+LA+V + N L Sbjct: 1626 IEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLL--- 1682 Query: 350 VSKSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSL--TPQNKEQDLSQA 523 AE+E+ LEQ + A ++++ D+ + SL T + E DL Q Sbjct: 1683 ---QAEVEELRATLEQ-TERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQL 1738 Query: 524 PSTASVNPAQQQLREPSGIMAFKFILGVALLVSSLRR 634 S V A + R A K I A++ L++ Sbjct: 1739 QS--EVEDASRDARNAEE-KAKKAITDAAMMAEELKK 1772
>MYSP_ONCVO (Q02171) Paramyosin| Length = 879 Score = 43.9 bits (102), Expect = 4e-04 Identities = 43/200 (21%), Positives = 99/200 (49%), Gaps = 11/200 (5%) Frame = +2 Query: 2 NEALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYS 181 N +T + + NL K++LE +L + +L+ A + + +E+A+ + A + Sbjct: 643 NGRITDLVSINNNLTAIKNKLETELSTAQADLDEATKELHAADERAN----RALADAARA 698 Query: 182 ADQLEVAQKHAAE-------LEVQVSALDQQLQEAE----IHYKNKVAEESEKLALVNTQ 328 +QL Q+H+ + LE QV L Q+QEAE + K +A+ ++ + T Sbjct: 699 VEQLHEEQEHSMKIDALRKSLEEQVKQLQVQIQEAEAAALLGGKRVIAKLETRIRDLETA 758 Query: 329 LNKLTQNVSKSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQ 508 L++ T+ + E + ++ +++++ + DE+ K V++ + + L+ L Q ++ Sbjct: 759 LDEETR---RHKETQGALRKKDRRIKEVQMQVDEEHKMFVMAQDTADRLLEKLNIQKRQL 815 Query: 509 DLSQAPSTASVNPAQQQLRE 568 +++ + A++ ++ RE Sbjct: 816 GEAESLTMANLQRVRRYQRE 835 Score = 40.8 bits (94), Expect = 0.003 Identities = 44/202 (21%), Positives = 87/202 (43%), Gaps = 14/202 (6%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSA 184 E ++ E +N V + ++ L + R+ L+A + + V+ K A Sbjct: 182 ERFEAQTIELSNKVEDLNRHVNDLAQQRQRLQAENNDLLKEIHDQKVQLDNLQHVKYQLA 241 Query: 185 DQLEVAQKHAAELEVQVSALDQQLQEAEIHYKN----------KVAEESEKLALVNTQLN 334 QLE A++ + E + S L QL + ++ + AE KLAL NT++ Sbjct: 242 QQLEEARRRLEDAERERSQLQAQLHQVQLELDSVRTALDEESAARAEAEHKLALANTEIT 301 Query: 335 KLTQNVSKSAEM-EKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKE-- 505 + + ++V+DL +K+ ++ +EQ + + E + L + + Sbjct: 302 QWKSKFDAEVALHHEEVEDLRKKMLQKQAEYEEQIEIMLQKISQLEKAKSRLQSEVEVLI 361 Query: 506 QDLSQAPST-ASVNPAQQQLRE 568 DL +A +T A + A++QL + Sbjct: 362 VDLEKAQNTIAILERAKEQLEK 383
>ROCK2_HUMAN (O75116) Rho-associated protein kinase 2 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2) Length = 1388 Score = 43.5 bits (101), Expect = 5e-04 Identities = 40/171 (23%), Positives = 84/171 (49%), Gaps = 7/171 (4%) Frame = +2 Query: 26 QEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQ 205 QE+ +L+ K LE+Q E+RKE + A + ++Q + YKT +L+ Sbjct: 829 QENNHLMEMKMNLEKQNAELRKERQDADGQMKELQDQLEAEQYFSTLYKT-QVRELKEEC 887 Query: 206 KHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSK----SAEME 373 + +L ++ Q+LQ+ ++ +A + E + L +L +++++ E E Sbjct: 888 EEKTKLGKELQQKKQELQDE----RDSLAAQLE-ITLTKADSEQLARSIAEEQYSDLEKE 942 Query: 374 KKVQDLEQKLQLAYSKSDEQAKDAVVST---RSREFSLDSLTPQNKEQDLS 517 K +++LE K +A K + KDA +++ +R + D N++++L+ Sbjct: 943 KIMKELEIKEMMARHKQELTEKDATIASLEETNRTLTSDVANLANEKEELN 993 Score = 30.8 bits (68), Expect = 3.6 Identities = 36/169 (21%), Positives = 73/169 (43%), Gaps = 8/169 (4%) Frame = +2 Query: 2 NEALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYS 181 N LTS + ANL +EK++L +L +V+++L ++E+ S IK K Sbjct: 975 NRTLTSDV---ANLANEKEELNNKLKDVQEQLSRL------KDEEISAAAIKAQFEKQLL 1025 Query: 182 ADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLAL-VNTQLNKLTQNVSK 358 ++ + A ++ + ++ + +E+ KL + + ++ KLTQ + K Sbjct: 1026 TER--TLKTQAVNKLAEIMNRKEPVKRGNDTDVRRKEKENRKLHMELKSEREKLTQQMIK 1083 Query: 359 SA----EMEKKVQDLEQ---KLQLAYSKSDEQAKDAVVSTRSREFSLDS 484 EM+ ++ + Q +LQ+ D + ++ LDS Sbjct: 1084 YQKELNEMQAQIAEESQIRIELQMTLDSKDSDIEQLRSQLQALHIGLDS 1132
>MYH4_MOUSE (Q5SX39) Myosin-4 (Myosin heavy chain, skeletal muscle, fetal)| Length = 1939 Score = 43.5 bits (101), Expect = 5e-04 Identities = 49/209 (23%), Positives = 87/209 (41%), Gaps = 19/209 (9%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKW-------- 160 E + ++ A ++ L ++L E+ + LE A + Q E RE ++ Sbjct: 1124 EEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLE 1183 Query: 161 DAYKTYSADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKL 340 +A + A + +KHA V+ L +Q+ + K K+ +E +L + L Sbjct: 1184 EATLQHEATAAALRKKHADS----VAELGEQIDNLQ-RVKQKLEKEKSELKMEIDDLASN 1238 Query: 341 TQNVSKS-AEMEKKVQDLEQKLQLAYSKSDEQ--------AKDAVVSTRSREFS--LDSL 487 + VSK+ +EK + LE +L +K +EQ + A + T S EFS LD Sbjct: 1239 METVSKAKGNLEKMCRTLEDQLSEVKTKEEEQQRLINELSTQKARLHTESGEFSRQLDEK 1298 Query: 488 TPQNKEQDLSQAPSTASVNPAQQQLREPS 574 + + T + ++QL E S Sbjct: 1299 DAMVSQLSRGKQAFTQQIEELKRQLEEES 1327 Score = 40.4 bits (93), Expect = 0.004 Identities = 44/196 (22%), Positives = 89/196 (45%), Gaps = 10/196 (5%) Frame = +2 Query: 11 LTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQ 190 L ++Q A+ + + ++ QL++ + +LEA + + + E + A K D+ Sbjct: 891 LQLQVQAEADGLADAEERCDQLIKTKIQLEAKIKELTERAEDEEEINAELTAKKRKLEDE 950 Query: 191 LEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEM 370 +K +LE+ ++ ++++ E NKV +E++A ++ + KLT+ E Sbjct: 951 CSELKKDIDDLELTLAKVEKEKHATE----NKVKNLTEEMAGLDENIAKLTKEKKALQEA 1006 Query: 371 EKKV-------QDLEQKLQLAYSKSDEQAKDAVVS-TRSREFSLDSLTPQNK-EQDLSQA 523 ++ +D L A +K ++Q D S + ++ +D + K E DL A Sbjct: 1007 HQQTLDDLQAEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLA 1066 Query: 524 -PSTASVNPAQQQLRE 568 ST + +QQL E Sbjct: 1067 QESTMDIENDKQQLDE 1082 Score = 33.1 bits (74), Expect = 0.72 Identities = 38/173 (21%), Positives = 76/173 (43%), Gaps = 35/173 (20%) Frame = +2 Query: 29 EHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQK 208 ++ +L++ K +LE + +++ E+E + N EE+A ++ DA A++L+ Q Sbjct: 1723 QNTSLINTKKKLETDISQIQGEMEDIVQEARNAEEKA--KKAITDA--AMMAEELKKEQD 1778 Query: 209 HAAELEVQVSALDQ----------------------QLQEAEIHYK---NKVAEESEK-- 307 +A LE ++Q Q+Q+ E + N+V E ++ Sbjct: 1779 TSAHLERMKKNMEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELENEVENEQKRNI 1838 Query: 308 -----LALVNTQLNKLTQNVSKSAEMEKKVQDLEQKLQL---AYSKSDEQAKD 442 L ++ +LT + + ++QDL KLQ AY + E+A++ Sbjct: 1839 EAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQTKVKAYKRQAEEAEE 1891
>SPO15_SCHPO (Q10411) Sporulation-specific protein 15| Length = 1957 Score = 43.5 bits (101), Expect = 5e-04 Identities = 38/187 (20%), Positives = 80/187 (42%) Frame = +2 Query: 2 NEALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYS 181 NE L ++ + + QL E EL+ + RTI +Q A + ++ Sbjct: 345 NEKLEKLLRNTIGSLKDSRTSNSQLEEEMVELKESNRTIHSQLTDAESKLSSFEQENKSL 404 Query: 182 ADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKS 361 ++ Q + + + V + QL+EA ++ +A + KLA +N++ + + + Sbjct: 405 KGSIDEYQNNLSSKDKMVKQVSSQLEEA----RSSLAHATGKLAEINSERDFQNKKI--- 457 Query: 362 AEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQAPSTASV 541 K + +EQ L+ + S + K+ ++ L++L Q KEQ + +S+ Sbjct: 458 ----KDFEKIEQDLRACLNSSSNELKEKSALIDKKDQELNNLREQIKEQKKVSESTQSSL 513 Query: 542 NPAQQQL 562 Q+ + Sbjct: 514 QSLQRDI 520
>MRCKG_MOUSE (Q80UW5) Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1)| (CDC42-binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma Length = 1551 Score = 43.5 bits (101), Expect = 5e-04 Identities = 39/153 (25%), Positives = 66/153 (43%), Gaps = 10/153 (6%) Frame = +2 Query: 41 LVHEKDQLEQQLLEVRKELEAAYRTIAN-QEEQASVREIKWDAYKTYSA---------DQ 190 L EKD+L+Q+L E + L + Q Q + W+A + +A Q Sbjct: 488 LQQEKDRLQQELTEAQAALRVQDAELCQAQNRQEEFLQRLWEAQEREAAAASQIQALNSQ 547 Query: 191 LEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEM 370 LE A ELE QV+ L Q++ + K + ++ A T + S+ A++ Sbjct: 548 LEEAWVVRRELEGQVTTLSQEVTRLQGQCKQESSQAKTVHAAPETNGIGSPEGQSQEAQL 607 Query: 371 EKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSRE 469 K+V L ++L+ A S+ K+ V+ E Sbjct: 608 RKEVAALREQLEHACSQGISVGKEEVLCRLQEE 640
>MYH10_RAT (Q9JLT0) Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle| myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B) Length = 1976 Score = 43.1 bits (100), Expect = 7e-04 Identities = 44/190 (23%), Positives = 84/190 (44%), Gaps = 12/190 (6%) Frame = +2 Query: 50 EKDQLEQQLLEVRKELEAAYRTIANQEE-----QASVREIKW---DAYKTYSADQLEVAQ 205 +K L ++L ++ ELE T A Q+E + V E+K D K + A ++ Q Sbjct: 1140 QKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEDETKNHEAQIQDMRQ 1199 Query: 206 KHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLN---KLTQNVSKSAEMEK 376 +HA LE L +QL++A+ +K + + + L N +L K+ Q V +E ++ Sbjct: 1200 RHATALE----ELSEQLEQAK-RFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKR 1254 Query: 377 KVQDLE-QKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQAPSTASVNPAQ 553 K D + Q+L S+ D + + LD+++ +E + + Sbjct: 1255 KKLDAQVQELHAKVSEGDRLRVELAEKANKLQNELDNVSTLLEEAEKKGMKFAKDAAGLE 1314 Query: 554 QQLREPSGIM 583 QL++ ++ Sbjct: 1315 SQLQDTQELL 1324 Score = 40.0 bits (92), Expect = 0.006 Identities = 44/181 (24%), Positives = 78/181 (43%), Gaps = 7/181 (3%) Frame = +2 Query: 41 LVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKH--- 211 L+ EK +LE ++ ++ +ELE + ++ ++ D T A + AQK Sbjct: 1727 LLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNTELAAERSAAQKSDNA 1786 Query: 212 AAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQL-NKLTQNVSKSAEMEKKVQD 388 +LE Q L +LQE E K+K L QL +L Q + A K V+ Sbjct: 1787 RQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRR 1846 Query: 389 LEQKLQLAYSKSDEQAKDAVVSTRSREFS---LDSLTPQNKEQDLSQAPSTASVNPAQQQ 559 E+KL+ + + +++ + A E + + L Q +E + + AS Q++ Sbjct: 1847 TEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRE 1906 Query: 560 L 562 L Sbjct: 1907 L 1907 Score = 37.0 bits (84), Expect = 0.050 Identities = 45/179 (25%), Positives = 80/179 (44%), Gaps = 3/179 (1%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSA 184 + L +++ + + D QQL KEL+A QE + +V+ K+ A T SA Sbjct: 1767 DTLNTELAAERSAAQKSDNARQQLERQNKELKAKL-----QELEGAVKS-KFKA--TISA 1818 Query: 185 DQLEVAQKHAAELEVQVSALDQQLQE--AEIHYKNKVAEESE-KLALVNTQLNKLTQNVS 355 LE ++ L++QL++ E NK+ +E KL + Q+ ++ Sbjct: 1819 ------------LEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHAD 1866 Query: 356 KSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQAPST 532 + E +K ++L+ +++E+A A S R + LD T N + LS+ ST Sbjct: 1867 QYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEAN--EGLSREVST 1923 Score = 35.0 bits (79), Expect = 0.19 Identities = 43/188 (22%), Positives = 81/188 (43%), Gaps = 15/188 (7%) Frame = +2 Query: 50 EKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKHAAELEV 229 E + E + L + + LE A A +E + ++++ D S+ + K+ ELE Sbjct: 1477 EAREKETKALSLARALEEALE--AKEEFERQNKQLRADMEDLMSSK--DDVGKNVHELEK 1532 Query: 230 QVSALDQQLQE-----AEIHYKNKVAEESEKLALVNTQLNKL----------TQNVSKSA 364 AL+QQ++E E+ + + E+++ VN Q K QN K Sbjct: 1533 SKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKR 1592 Query: 365 EMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQAPSTASVN 544 + K+V++LE +L+ +Q AV S + E L L Q + + ++ + Sbjct: 1593 LLLKQVRELEAELE----DERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLR 1648 Query: 545 PAQQQLRE 568 Q Q+++ Sbjct: 1649 KLQAQMKD 1656 Score = 33.1 bits (74), Expect = 0.72 Identities = 30/144 (20%), Positives = 60/144 (41%) Frame = +2 Query: 50 EKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKHAAELEV 229 + ++ ++ LL+ +ELEA Q A + K + Q+E A K E+ Sbjct: 1586 QNEEKKRLLLKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIK 1645 Query: 230 QVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEMEKKVQDLEQKLQL 409 Q+ L Q+++ + + A E A KL ++ ++++++ E+ + Sbjct: 1646 QLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRH 1705 Query: 410 AYSKSDEQAKDAVVSTRSREFSLD 481 A + DE A + S + LD Sbjct: 1706 AEQERDELADEIANSASGKSALLD 1729
>MYH10_MOUSE (Q61879) Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle| myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B) Length = 1976 Score = 43.1 bits (100), Expect = 7e-04 Identities = 44/190 (23%), Positives = 84/190 (44%), Gaps = 12/190 (6%) Frame = +2 Query: 50 EKDQLEQQLLEVRKELEAAYRTIANQEE-----QASVREIKW---DAYKTYSADQLEVAQ 205 +K L ++L ++ ELE T A Q+E + V E+K D K + A ++ Q Sbjct: 1140 QKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEDETKNHEAQIQDMRQ 1199 Query: 206 KHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLN---KLTQNVSKSAEMEK 376 +HA LE L +QL++A+ +K + + + L N +L K+ Q V +E ++ Sbjct: 1200 RHATALE----ELSEQLEQAK-RFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKR 1254 Query: 377 KVQDLE-QKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQAPSTASVNPAQ 553 K D + Q+L S+ D + + LD+++ +E + + Sbjct: 1255 KKLDAQVQELHAKVSEGDRLRVELAEKANKLQNELDNVSTLLEEAEKKGIKFAKDAAGLE 1314 Query: 554 QQLREPSGIM 583 QL++ ++ Sbjct: 1315 SQLQDTQELL 1324 Score = 40.0 bits (92), Expect = 0.006 Identities = 44/181 (24%), Positives = 78/181 (43%), Gaps = 7/181 (3%) Frame = +2 Query: 41 LVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKH--- 211 L+ EK +LE ++ ++ +ELE + ++ ++ D T A + AQK Sbjct: 1727 LLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNTELAAERSAAQKSDNA 1786 Query: 212 AAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQL-NKLTQNVSKSAEMEKKVQD 388 +LE Q L +LQE E K+K L QL +L Q + A K V+ Sbjct: 1787 RQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRR 1846 Query: 389 LEQKLQLAYSKSDEQAKDAVVSTRSREFS---LDSLTPQNKEQDLSQAPSTASVNPAQQQ 559 E+KL+ + + +++ + A E + + L Q +E + + AS Q++ Sbjct: 1847 TEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRE 1906 Query: 560 L 562 L Sbjct: 1907 L 1907 Score = 37.0 bits (84), Expect = 0.050 Identities = 45/179 (25%), Positives = 80/179 (44%), Gaps = 3/179 (1%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSA 184 + L +++ + + D QQL KEL+A QE + +V+ K+ A T SA Sbjct: 1767 DTLNTELAAERSAAQKSDNARQQLERQNKELKAKL-----QELEGAVKS-KFKA--TISA 1818 Query: 185 DQLEVAQKHAAELEVQVSALDQQLQE--AEIHYKNKVAEESE-KLALVNTQLNKLTQNVS 355 LE ++ L++QL++ E NK+ +E KL + Q+ ++ Sbjct: 1819 ------------LEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHAD 1866 Query: 356 KSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQAPST 532 + E +K ++L+ +++E+A A S R + LD T N + LS+ ST Sbjct: 1867 QYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEAN--EGLSREVST 1923 Score = 35.0 bits (79), Expect = 0.19 Identities = 43/188 (22%), Positives = 81/188 (43%), Gaps = 15/188 (7%) Frame = +2 Query: 50 EKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKHAAELEV 229 E + E + L + + LE A A +E + ++++ D S+ + K+ ELE Sbjct: 1477 EAREKETKALSLARALEEALE--AKEEFERQNKQLRADMEDLMSSK--DDVGKNVHELEK 1532 Query: 230 QVSALDQQLQE-----AEIHYKNKVAEESEKLALVNTQLNKL----------TQNVSKSA 364 AL+QQ++E E+ + + E+++ VN Q K QN K Sbjct: 1533 SKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKR 1592 Query: 365 EMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQAPSTASVN 544 + K+V++LE +L+ +Q AV S + E L L Q + + ++ + Sbjct: 1593 LLLKQVRELEAELE----DERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLR 1648 Query: 545 PAQQQLRE 568 Q Q+++ Sbjct: 1649 KLQAQMKD 1656 Score = 33.1 bits (74), Expect = 0.72 Identities = 30/144 (20%), Positives = 60/144 (41%) Frame = +2 Query: 50 EKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKHAAELEV 229 + ++ ++ LL+ +ELEA Q A + K + Q+E A K E+ Sbjct: 1586 QNEEKKRLLLKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIK 1645 Query: 230 QVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEMEKKVQDLEQKLQL 409 Q+ L Q+++ + + A E A KL ++ ++++++ E+ + Sbjct: 1646 QLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRH 1705 Query: 410 AYSKSDEQAKDAVVSTRSREFSLD 481 A + DE A + S + LD Sbjct: 1706 AEQERDELADEIANSASGKSALLD 1729
>ROCK2_RAT (Q62868) Rho-associated protein kinase 2 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 2) (p164 ROCK-2) (RhoA-binding kinase 2) (p150 ROK-alpha) (ROKalpha) Length = 1379 Score = 43.1 bits (100), Expect = 7e-04 Identities = 40/171 (23%), Positives = 83/171 (48%), Gaps = 7/171 (4%) Frame = +2 Query: 26 QEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQ 205 QE+ +L+ K LE+Q E+RKE + A + ++Q + YKT +L+ Sbjct: 820 QENNHLMEMKMNLEKQNAELRKERQDADGQMKELQDQLEAEQYFSTLYKT-QVRELKEEN 878 Query: 206 KHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSK----SAEME 373 + +L ++ Q LQ+ ++ +A + E + L +L +++++ E E Sbjct: 879 EEKTKLCKELQQKKQDLQDE----RDSLAAQLE-ITLTKADSEQLARSIAEEQYSDLEKE 933 Query: 374 KKVQDLEQKLQLAYSKSDEQAKDAVVST---RSREFSLDSLTPQNKEQDLS 517 K +++LE K +A K + KDA +++ +R + D N++++L+ Sbjct: 934 KIMKELEIKEMMARHKQELTEKDATIASLEETNRTLTSDVANLANEKEELN 984
>CN145_MOUSE (Q8BI22) Protein C14orf145 homolog| Length = 524 Score = 43.1 bits (100), Expect = 7e-04 Identities = 49/188 (26%), Positives = 93/188 (49%), Gaps = 15/188 (7%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLE-------QQLLEVRKELEAAYRTIANQEEQASVREIKWD 163 E L +++ + E+D+L+ QQ+ +RKEL A QEE+ +E K + Sbjct: 6 ETLVQLTEKNNQFIKERDELKSQLCAALQQIENLRKELNDVLSKRALQEEELHCKEKKLN 65 Query: 164 AYKTYSAD-QLEVAQK----HAAELEVQVSALDQ-QLQEAEIHYKNKVAEESEKLALVNT 325 +++ A+ +LEV H E E++ + Q Q++ +IH + ++ E L + Sbjct: 66 DIESHQAELELEVKNSLDTIHRLENELKRQSKSQSQIKAEKIHLEEEITE------LKKS 119 Query: 326 QLNKLTQNVSKSAEMEKKVQDLEQ-KLQLAYSKSDEQ-AKDAVVSTRSREFSLDSLTPQN 499 Q +Q+ K EM++ ++DL + LA ++E+ AK AV R+ S + ++ Sbjct: 120 Q----SQDKVKLLEMQESIKDLSAIRADLANKLAEEEKAKKAVF----RDLSELTAQVKS 171 Query: 500 KEQDLSQA 523 KE++ + A Sbjct: 172 KEEETATA 179 Score = 34.7 bits (78), Expect = 0.25 Identities = 35/153 (22%), Positives = 64/153 (41%), Gaps = 12/153 (7%) Frame = +2 Query: 35 ANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASV-------REIKWDAYKTYSADQL 193 AN + E+++ ++ + EL A ++ +EE A+ R++ + S+ Sbjct: 145 ANKLAEEEKAKKAVFRDLSELTAQVKS--KEEETATAITQLKLERDVHQRELEDLSSSLE 202 Query: 194 EVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNT---QLNKLTQNVSKSA 364 V KH ++ + ++ EAE H + AE E + QL KL K Sbjct: 203 SVKLKHEQNIQELMKHFKKEKSEAESHIRMLKAESLEDKNMAKAHLGQLEKLKSQCEKLT 262 Query: 365 EMEKKVQDLEQKLQLAYS--KSDEQAKDAVVST 457 E ++ +KL+L Y K + K+ +ST Sbjct: 263 EELTHTENENKKLKLKYQSLKEELDKKEKYIST 295
>GOGA1_HUMAN (Q92805) Golgin subfamily A member 1 (Golgin-97)| Length = 767 Score = 42.7 bits (99), Expect = 0.001 Identities = 37/167 (22%), Positives = 72/167 (43%), Gaps = 4/167 (2%) Frame = +2 Query: 11 LTSKMQE----HANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTY 178 LT+++QE NL +D++++ ++EL + +EE E + +A Sbjct: 149 LTAQLQEMKNQSMNLFQRRDEMDELEGFQQQELSKIKHMLLKKEESLGKMEQELEA---- 204 Query: 179 SADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSK 358 +L Q+ S L Q+L+E + HY + +A +K+T K Sbjct: 205 RTRELSRTQEELMNSNQMSSDLSQKLEELQRHYSTLEEQRDHVIASKTGAESKITALEQK 264 Query: 359 SAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQN 499 E++ +Q L LQ +++ E+ +D + + + SL+ QN Sbjct: 265 EQELQALIQQLSIDLQKVTAETQEK-EDVITHLQEKVASLEKRLEQN 310 Score = 31.6 bits (70), Expect = 2.1 Identities = 31/149 (20%), Positives = 68/149 (45%), Gaps = 18/149 (12%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQQLLEVRKELE----------AAYRTIANQ------EEQ 136 + L + QE +++ + LEQQ LE + LE AA +T A Q +E Sbjct: 385 QELAAANQESSHVQQQALALEQQFLERTQALEAQIVALERMRAADQTTAEQGMRQLEQEN 444 Query: 137 ASVREIKWDAYKTYSADQLEV--AQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKL 310 A+++E + + ++ Q E+ ++ ++ E+ A+ Q L+E + + + Sbjct: 445 AALKECRNEYERSLQNHQFELKKLKEEWSQREIVSVAMAQALEEVRKQREEFQQQAANLT 504 Query: 311 ALVNTQLNKLTQNVSKSAEMEKKVQDLEQ 397 A+++ + L + + E+++ LE+ Sbjct: 505 AIIDEKEQNLREKTEVLLQKEQEILQLER 533 Score = 30.4 bits (67), Expect = 4.6 Identities = 38/166 (22%), Positives = 67/166 (40%), Gaps = 1/166 (0%) Frame = +2 Query: 26 QEHAN-LVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVA 202 +EH L+ EK EQ L + R++L AA ++ A + Sbjct: 314 EEHVQELLKEKTLAEQNLEDTRQQLLAA---------------------RSSQAKAINTL 352 Query: 203 QKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEMEKKV 382 + ELE + A ++QLQ++ K VA + TQ+ +L +S+ ++++ Sbjct: 353 ETRVRELEQTLQASEEQLQQS----KGIVAAQ-------ETQIQELAAANQESSHVQQQA 401 Query: 383 QDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQ 520 LEQ+ QA +A + R + D T + + L Q Sbjct: 402 LALEQQF-----LERTQALEAQIVALERMRAADQTTAEQGMRQLEQ 442
>MYSP_DERFA (Q967Z0) Paramyosin (Allergen Der f 11) (Antigen Df642) (Fragment)| Length = 692 Score = 42.7 bits (99), Expect = 0.001 Identities = 42/194 (21%), Positives = 90/194 (46%), Gaps = 14/194 (7%) Frame = +2 Query: 17 SKMQEHANLVHEKDQLEQQLLEVRKELEAAYR---TIANQEEQ------ASVREIKWDAY 169 S++ + +HE++ ++L R EL AAY+ T+ QEE A + +++ D Y Sbjct: 352 SQLNDAHRRIHEQEIEIKRLENERDELSAAYKEAETLRKQEEAKNQRLIAELAQVRHD-Y 410 Query: 170 KTYSADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQN 349 + A + E + + ++++ L+ +L EAE K ++A +K T+L +L+ + Sbjct: 411 EKRLAQKDEEIEALRKQYQIEIEQLNMRLAEAEAKLKTEIARLKKKYQAQITEL-ELSLD 469 Query: 350 VSKSAEMEKKVQDLEQKLQLA-----YSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDL 514 + A ++ + +Q LQ+ Y + Q + AV + +L + +E + Sbjct: 470 AANKANIDLQKTIKKQALQITELQAHYDEVHRQLQQAVDQLGVTQRRCQALQAELEEMRI 529 Query: 515 SQAPSTASVNPAQQ 556 + + + A+Q Sbjct: 530 ALEQANRAKRQAEQ 543
>MYS_AEQIR (P24733) Myosin heavy chain, striated muscle| Length = 1938 Score = 42.7 bits (99), Expect = 0.001 Identities = 45/202 (22%), Positives = 99/202 (49%), Gaps = 25/202 (12%) Frame = +2 Query: 8 ALTSKMQEHANLVHEKD----QLEQQLLEVRKELEAAYRTIANQEEQASV--REI----- 154 +L SK+++ NLV + +L+ ++ E+ +ELEA A E+Q + RE+ Sbjct: 1086 SLNSKLEDEQNLVSQLQRKIKELQARIEELEEELEAERNARAKVEKQRAELNRELEELGE 1145 Query: 155 KWDAYKTYSADQLEVAQKHAAEL--------------EVQVSALDQQLQEAEIHYKNKVA 292 + D ++ Q+E+ +K AEL E Q+SAL ++ Q+A N++A Sbjct: 1146 RLDEAGGATSAQIELNKKREAELLKIRRDLEEASLQHEAQISALRKKHQDA----ANEMA 1201 Query: 293 EESEKLALVNTQLNKLTQNVSKSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREF 472 ++ ++L V ++L K ++++++ DLE Q+ ++ ++ + V+ + Sbjct: 1202 DQVDQLQKVKSKLEK------DKKDLKREMDDLES--QMTHNMKNKGCSEKVMKQFESQM 1253 Query: 473 SLDSLTPQNKEQDLSQAPSTAS 538 S + ++ ++ +++ S S Sbjct: 1254 SDLNARLEDSQRSINELQSQKS 1275 Score = 33.9 bits (76), Expect = 0.42 Identities = 39/204 (19%), Positives = 97/204 (47%), Gaps = 15/204 (7%) Frame = +2 Query: 2 NEALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYS 181 N+ + + +++ +K +LE + ++ +L+ + + +E+ ++ DA + Sbjct: 1707 NDRVNELTSQVSSVQGQKRKLEGDINAMQTDLDEMHGELKGADERC--KKAMADAARL-- 1762 Query: 182 ADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEE----SEKLALVNTQLNKLTQN 349 AD+L Q H+ ++E L+ Q++E +I A + + + +++++L Sbjct: 1763 ADELRAEQDHSNQVEKVRKNLESQVKEFQIRLDEAEASSLKGGKKMIQKLESRVHELEAE 1822 Query: 350 VS----KSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNK--EQD 511 + + AE +K ++ +++L+ ++DE K+ R +E +D L + K ++ Sbjct: 1823 LDNEQRRHAETQKNMRKADRRLKELAFQADEDRKN---QERLQEL-IDKLNAKIKTFKRQ 1878 Query: 512 LSQAPSTASVN-----PAQQQLRE 568 + +A A++N AQ +L E Sbjct: 1879 VEEAEEIAAINLAKYRKAQHELEE 1902
>YMS1_YEAST (Q05050) Hypothetical 93.3 kDa protein in TAP42-CYK2 intergenic| region Length = 843 Score = 42.4 bits (98), Expect = 0.001 Identities = 40/169 (23%), Positives = 75/169 (44%), Gaps = 6/169 (3%) Frame = +2 Query: 20 KMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEV 199 K Q L EK +L+Q L E K+ E ++ R+ + + K Y D Sbjct: 501 KKQMQQELKDEKARLDQDLEEWGKKCE---------QDITEARKEQEELLKPYHDDLANA 551 Query: 200 AQKHAAELEV--QVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEME 373 +H +E +++A +LQ+A + +K K++ L + Q N+ + K E+ Sbjct: 552 EAEHKTLVEERDEINAEISRLQDAIVDHKRKISGYGNDL---DAQKNRNIREDDKLLELG 608 Query: 374 KKVQDLEQKLQ----LAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQ 508 + + LE L + +K+ EQA+ + R ++ +DSL + K + Sbjct: 609 QTKESLESHLNDDVIILANKAKEQAELSTKEARLKQLEVDSLINERKSE 657 Score = 35.0 bits (79), Expect = 0.19 Identities = 45/235 (19%), Positives = 89/235 (37%), Gaps = 48/235 (20%) Frame = +2 Query: 2 NEALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIA---NQEEQASVREIKWD--- 163 ++ L + EH LV E+D++ ++ ++ + R I+ N + R I+ D Sbjct: 545 HDDLANAEAEHKTLVEERDEINAEISRLQDAIVDHKRKISGYGNDLDAQKNRNIREDDKL 604 Query: 164 -------------------AYKTYSADQLEVAQKHAAELEVQVSAL----DQQLQEAEIH 274 + +Q E++ K A +++V +L +L EI Sbjct: 605 LELGQTKESLESHLNDDVIILANKAKEQAELSTKEARLKQLEVDSLINERKSELNATEIE 664 Query: 275 YK-------------------NKVAEESEKLALVNTQLNKLTQNVSKSAEMEKKVQDLEQ 397 K +K+ EE K + T LTQN S +EK V+DL Sbjct: 665 LKKEKLNLLEAMKDVASARGDDKIDEEKVKKLIGMTSEEYLTQNKS----VEKNVEDLPT 720 Query: 398 KLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQAPSTASVNPAQQQL 562 +L+ + DE K+ +V ++ D + ++ ++ S ++++ Sbjct: 721 QLE-KIEEGDELKKEEIVGAETKNSGGDGVPVSTAAKEATETSSAVQTKEPEEKI 774
>HMMR_RAT (P97779) Hyaluronan-mediated motility receptor (Intracellular| hyaluronic acid-binding protein) (Receptor for hyaluronan-mediated motility) Length = 498 Score = 42.4 bits (98), Expect = 0.001 Identities = 43/190 (22%), Positives = 85/190 (44%), Gaps = 2/190 (1%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSA 184 E L + E + +++Q E+ + ++ +E ++ + ++ +EI+ + A Sbjct: 161 EQLKLALDELDAVQQKEEQSEKLVKQLEEETKSTAEQLRRLDDLLREKEIELEKRTAAHA 220 Query: 185 DQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSA 364 +AQ+ ++ + + QL+ YK+ +E E L L N L + K A Sbjct: 221 QATVIAQEKYSDTAQTLRDVTAQLES----YKSSTLKEIEDLKLENLTLQE------KVA 270 Query: 365 EMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQAPST--AS 538 EK+V+D++Q++ A S + E AK VV +L KE ++ + S+ Sbjct: 271 MAEKRVEDVQQQILTAESTNQEYAK--VVQDLQNSSTL-------KEAEIKEITSSYLEK 321 Query: 539 VNPAQQQLRE 568 + Q QLR+ Sbjct: 322 ITDLQNQLRQ 331
>MYH10_HUMAN (P35580) Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle| myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B) Length = 1976 Score = 42.4 bits (98), Expect = 0.001 Identities = 46/188 (24%), Positives = 85/188 (45%), Gaps = 15/188 (7%) Frame = +2 Query: 50 EKDQLEQQLLEVRKELEAAYRTIANQEE-----QASVREIKW---DAYKTYSADQLEVAQ 205 +K L ++L ++ ELE T A Q+E + V E+K + K + A ++ Q Sbjct: 1140 QKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQ 1199 Query: 206 KHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLN---KLTQNVSKSAEMEK 376 +HA LE L +QL++A+ +K + + + L N +L K+ Q V +E ++ Sbjct: 1200 RHATALE----ELSEQLEQAK-RFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKR 1254 Query: 377 KVQDLE-QKLQLAYSKSDEQAKDAVVSTRSREFSLD---SLTPQNKEQDLSQAPSTASVN 544 K D + Q+L S+ D + + LD +L + +++ + A AS+ Sbjct: 1255 KKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLE 1314 Query: 545 PAQQQLRE 568 Q +E Sbjct: 1315 SQLQDTQE 1322 Score = 39.7 bits (91), Expect = 0.008 Identities = 44/193 (22%), Positives = 82/193 (42%), Gaps = 7/193 (3%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSA 184 + +T+ + L+ EK +LE ++ ++ +ELE + ++ ++ D A Sbjct: 1715 DEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELA 1774 Query: 185 DQLEVAQKH---AAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQL-NKLTQNV 352 + AQK +LE Q L +LQE E K+K L QL +L Q Sbjct: 1775 AERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEA 1834 Query: 353 SKSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFS---LDSLTPQNKEQDLSQA 523 + A K V+ E+KL+ + + +++ + A E + + L Q +E + Sbjct: 1835 KERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEAT 1894 Query: 524 PSTASVNPAQQQL 562 + AS Q++L Sbjct: 1895 RANASRRKLQREL 1907 Score = 35.0 bits (79), Expect = 0.19 Identities = 43/188 (22%), Positives = 81/188 (43%), Gaps = 15/188 (7%) Frame = +2 Query: 50 EKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKHAAELEV 229 E + E + L + + LE A A +E + ++++ D S+ + K+ ELE Sbjct: 1477 EAREKETKALSLARALEEALE--AKEEFERQNKQLRADMEDLMSSK--DDVGKNVHELEK 1532 Query: 230 QVSALDQQLQE-----AEIHYKNKVAEESEKLALVNTQLNKL----------TQNVSKSA 364 AL+QQ++E E+ + + E+++ VN Q K QN K Sbjct: 1533 SKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKR 1592 Query: 365 EMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQAPSTASVN 544 + K+V++LE +L+ +Q AV S + E L L Q + + ++ + Sbjct: 1593 LLIKQVRELEAELE----DERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLR 1648 Query: 545 PAQQQLRE 568 Q Q+++ Sbjct: 1649 KLQAQMKD 1656 Score = 32.3 bits (72), Expect = 1.2 Identities = 29/144 (20%), Positives = 60/144 (41%) Frame = +2 Query: 50 EKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKHAAELEV 229 + ++ ++ L++ +ELEA Q A + K + Q+E A K E+ Sbjct: 1586 QNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIK 1645 Query: 230 QVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEMEKKVQDLEQKLQL 409 Q+ L Q+++ + + A E A KL ++ ++++++ E+ + Sbjct: 1646 QLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRH 1705 Query: 410 AYSKSDEQAKDAVVSTRSREFSLD 481 A + DE A + S + LD Sbjct: 1706 AEQERDELADEITNSASGKSALLD 1729
>PCNT_MOUSE (P48725) Pericentrin| Length = 1920 Score = 42.4 bits (98), Expect = 0.001 Identities = 37/161 (22%), Positives = 75/161 (46%), Gaps = 27/161 (16%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQQLLEVRKEL-------------------EAAYRTIANQ 127 EAL K + L+ E + L +QL + +EL EA R A Q Sbjct: 1124 EALGKKEESEQQLILELEDLRKQLEQAARELLTLKEEKSVLWNQKETLTNEAKEREAALQ 1183 Query: 128 EEQASVREIKWDAYKTYSADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEK 307 EE S+ ++W++ K ++K A L Q+ L+ +L++ + ++ A+ +E+ Sbjct: 1184 EEVESLTRVQWESRKQ--------SEKDRATLLSQMRVLESELEDQLVQHRG-CAQLAEE 1234 Query: 308 LALVNTQLNKLTQNV--------SKSAEMEKKVQDLEQKLQ 406 +A + QL L +++ ++AE + + ++ +Q++Q Sbjct: 1235 VATLKQQLAALDKHLRSQRQFMDDQAAERDDEREEFQQEIQ 1275 Score = 39.3 bits (90), Expect = 0.010 Identities = 57/240 (23%), Positives = 90/240 (37%), Gaps = 46/240 (19%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQ-------------EEQASV 145 +A QE N Q QQLL +R ELE +R+ + E + Sbjct: 638 DAFLRDAQEKHNHEQLLQQGHQQLLALRMELETKHRSELTEQLASSESRRQALLETHVAE 697 Query: 146 REIKWDA----------------YKTYSADQLEVAQKHAAELEVQVSALDQQLQEAEIHY 277 ++K +A Y AD + +H LE+ + L++QLQ+ E + Sbjct: 698 LQVKHNAEISALEKRHLSNLDELESCYVADVQTIRDEHQQALELLRAELEEQLQKKESCH 757 Query: 278 KNKVAEESEKLALVNTQLNKLTQNVSKSAEMEKKVQDLEQ------KLQLAYSKSDEQA- 436 + + +E E L Q + Q+V S ME Q +E LQ A+ + A Sbjct: 758 REMLTQELENL---KRQHAEELQSVRDSLRMEMSAQHIENGKGPAADLQGAHQQDPAMAL 814 Query: 437 ----------KDAVVSTRSREFSLDSLTPQNKEQDLSQAPSTASVNPAQQQLREPSGIMA 586 DAV+ R + L Q Q+L A T + +Q +L +P + A Sbjct: 815 HNEGHLLVEDGDAVL----RSVDAEGLLHQAGPQELGDA-HTVEMQKSQAELAKPQELQA 869
>MYH6_MOUSE (Q02566) Myosin heavy chain, cardiac muscle alpha isoform| (MyHC-alpha) Length = 1938 Score = 42.4 bits (98), Expect = 0.001 Identities = 40/167 (23%), Positives = 78/167 (46%), Gaps = 3/167 (1%) Frame = +2 Query: 53 KDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKHAA---EL 223 K ++E++L E +E+E A R N + DA + L V +K E+ Sbjct: 1571 KAEIERKLAEKDEEMEQAKR---NHLRMVDSLQTSLDAETRSRNEALRVKKKMEGDLNEM 1627 Query: 224 EVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEMEKKVQDLEQKL 403 E+Q+S ++ EA+ H KN A L +TQL +L V + ++++ + +E++ Sbjct: 1628 EIQLSQANRIASEAQKHLKNSQAH------LKDTQL-QLDDAVHANDDLKENIAIVERRN 1680 Query: 404 QLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQAPSTASVN 544 L ++ +E + RSR+ + L ++ L + +T+ +N Sbjct: 1681 NLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLIN 1727 Score = 40.4 bits (93), Expect = 0.004 Identities = 40/181 (22%), Positives = 83/181 (45%), Gaps = 35/181 (19%) Frame = +2 Query: 29 EHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQAS---------VREIKWDA----- 166 ++ +L+++K ++E L +++ E+E A + N EE+A E+K + Sbjct: 1721 QNTSLINQKKKMESDLTQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAH 1780 Query: 167 ----------------YKTYSADQLEV--AQKHAAELEVQVSALDQQLQEAEIHYKNKVA 292 ++ A+Q+ + +K +LE +V L+ +L EAE + + A Sbjct: 1781 LERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENEL-EAE---QKRNA 1836 Query: 293 EESEKLALVNTQLNKLTQNVSKSAEMEKKVQDLEQKLQL---AYSKSDEQAKDAVVSTRS 463 E + + ++ +LT + + ++QDL KLQL AY + E+A++ + S Sbjct: 1837 ESVKGMRKSERRIKELTYQTEEDKKNLMRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLS 1896 Query: 464 R 466 + Sbjct: 1897 K 1897
>MYSP_DIRIM (P13392) Paramyosin (Fragment)| Length = 848 Score = 42.4 bits (98), Expect = 0.001 Identities = 43/200 (21%), Positives = 98/200 (49%), Gaps = 11/200 (5%) Frame = +2 Query: 2 NEALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYS 181 N +T + + NL K++LE +L + +L+ A + + +E+A+ + A + Sbjct: 616 NARITDLVSINNNLTAIKNKLETELSTAQADLDEATKELHAADERAN----RALADAARA 671 Query: 182 ADQLEVAQKHAAE-------LEVQVSALDQQLQEAE----IHYKNKVAEESEKLALVNTQ 328 +QL Q+H+ + LE QV L Q+QEAE + K +A+ ++ + T Sbjct: 672 VEQLHEEQEHSMKIDALRKSLEEQVKQLQVQIQEAEAAALLGGKRVIAKLETRIRDLETA 731 Query: 329 LNKLTQNVSKSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQ 508 L++ T+ + E + ++ +++++ + DE+ K V++ + + L+ L Q + Sbjct: 732 LDEETR---RHKETQGALRKKDRRIKEVQMQVDEEHKMFVMAQDTADRLLEKLNIQKWQL 788 Query: 509 DLSQAPSTASVNPAQQQLRE 568 +++ + A++ ++ RE Sbjct: 789 GEAESLTMANLQRVRRYQRE 808 Score = 40.8 bits (94), Expect = 0.003 Identities = 44/202 (21%), Positives = 87/202 (43%), Gaps = 14/202 (6%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSA 184 E ++ E +N V + ++ L + R+ L+A + + V+ K A Sbjct: 155 ERFEAQTIELSNKVEDLNRHVNDLAQQRQRLQAENNDLLKEIHDQKVQLDNLQHVKYQLA 214 Query: 185 DQLEVAQKHAAELEVQVSALDQQLQEAEIHYKN----------KVAEESEKLALVNTQLN 334 QLE A++ + E + S L QL + ++ + AE KLAL NT++ Sbjct: 215 QQLEEARRRLEDAERERSQLQAQLHQVQLELDSVRTALDEESAARAEAEHKLALANTEIT 274 Query: 335 KLTQNVSKSAEM-EKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKE-- 505 + + ++V+DL +K+ ++ +EQ + + E + L + + Sbjct: 275 QWKSKFDAEVALHHEEVEDLRKKMLQKQAEYEEQIEIMLQKISQLEKAKSRLQSEVEVLI 334 Query: 506 QDLSQAPST-ASVNPAQQQLRE 568 DL +A +T A + A++QL + Sbjct: 335 VDLEKAQNTIAILERAKEQLEK 356
>ARFG_ARATH (P93022) Auxin response factor 7 (Non-phototropic hypocotyl 4)| (Protein BIPOSTO) (Auxin-responsive protein IAA21/IAA23/IAA25) Length = 1164 Score = 42.0 bits (97), Expect = 0.002 Identities = 35/170 (20%), Positives = 79/170 (46%), Gaps = 10/170 (5%) Frame = +2 Query: 26 QEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQ 205 Q+H+N + Q +QQLL+ +++ + + ++Q ++++ +++S Q + Q Sbjct: 541 QQHSNNNQSQSQQQQQLLQQQQQQQLQQQHQQPLQQQTQQQQLRTQPLQSHSHPQPQQLQ 600 Query: 206 KH-AAELEV--------QVSALDQQLQEAEIHY-KNKVAEESEKLALVNTQLNKLTQNVS 355 +H +L+V Q +A Q Q+A H+ + ++ S +++ + L Q+ Sbjct: 601 QHKLQQLQVPQNQLYNGQQAAQQHQSQQASTHHLQPQLVSGSMASSVITPPSSSLNQSFQ 660 Query: 356 KSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKE 505 + + K++Q L + S+S +V+ T +L S PQ + Sbjct: 661 QQQQQSKQLQQAHHHLGASTSQS------SVIETSKSSSNLMSAPPQETQ 704
>PLCB1_RAT (P10687) 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase| beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C-beta-1) (PLC-beta-1) (PLC-I) (PLC-154) Length = 1216 Score = 42.0 bits (97), Expect = 0.002 Identities = 47/210 (22%), Positives = 99/210 (47%), Gaps = 21/210 (10%) Frame = +2 Query: 8 ALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSAD 187 AL ++M + L+ KD+ +QQLL +R+E + + + + ++++ D + + Sbjct: 996 ALDAEMTQ--KLIDLKDKQQQQLLNLRQEQYYSEKYQKREHIKLLIQKLT-DVAEECQNN 1052 Query: 188 QL----EVAQKHAAELEVQVSALDQQLQE--AEIHYKNKVAEESEKLALVNTQLNKLTQN 349 QL E+ +K EL+ +D++ QE E K+K E EK ++ + + ++ Q Sbjct: 1053 QLKKLKEICEKEKKELK---KKMDKKRQEKITEAKSKDKSQMEEEKTEMIRSYIQEVVQY 1109 Query: 350 VSKSAEMEKKVQD-------------LEQKLQLAYSKSDE-QAKDAVVSTRSREFSLDSL 487 + + E + K Q+ L++K +L E Q K + EF +++ Sbjct: 1110 IKRLEEAQSKRQEKLVEKHKEIRQQILDEKPKLQMELEQEYQDKFKRLPLEILEFVQEAM 1169 Query: 488 TPQ-NKEQDLSQAPSTASVNPAQQQLREPS 574 + +++ + AP + + +PA+ L+ PS Sbjct: 1170 KGKVSEDSNHGSAPPSLASDPAKVNLKSPS 1199
>GOGA4_HUMAN (Q13439) Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa| golgin) (Golgin-245) (Protein 72.1) Length = 2230 Score = 42.0 bits (97), Expect = 0.002 Identities = 42/161 (26%), Positives = 76/161 (47%), Gaps = 28/161 (17%) Frame = +2 Query: 53 KDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQK-HAAELEV 229 K ++++Q+ + K E I+ Q+E + V++ D K S +Q+ QK H EL Sbjct: 434 KAEMDEQIKTIEKTSEE--ERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELAR 491 Query: 230 QVSALDQQLQ--EAEIHYKNKVA---------------EESEKLALVNTQLNK---LTQN 349 + L ++LQ E E + KVA E+ E LAL +L K LT++ Sbjct: 492 KEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTES 551 Query: 350 VSKSAEMEKKVQ-------DLEQKLQLAYSKSDEQAKDAVV 451 +K +++++ + +LE L+ + ++ Q+KD V Sbjct: 552 ENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAV 592 Score = 40.4 bits (93), Expect = 0.004 Identities = 42/194 (21%), Positives = 84/194 (43%), Gaps = 20/194 (10%) Frame = +2 Query: 59 QLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKHAAELEVQVS 238 QL+Q+LL++ E + +A E Q + DA+K D ++ +K +E+E +V Sbjct: 823 QLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVK 882 Query: 239 ALDQQLQEAEIHYKNKVAEESEKLAL------------VNTQLNKLTQNVSK-------- 358 +L Q+ E+++ NK E+++++ + ++ LTQ +S Sbjct: 883 SL-TQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHIL 941 Query: 359 SAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQAPSTAS 538 + E E K ++ E+K++ K+ E + +E L +N +LSQ + Sbjct: 942 NEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKK-ELENTALELSQKEKQFN 1000 Query: 539 VNPAQQQLREPSGI 580 + +GI Sbjct: 1001 AKMLEMAQANSAGI 1014 Score = 39.3 bits (90), Expect = 0.010 Identities = 44/164 (26%), Positives = 77/164 (46%), Gaps = 15/164 (9%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSA 184 +AL ++ + L+ E+D+ ++ + LEA + + +QAS K D +++Y + Sbjct: 752 KALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASA---KLDVFQSYQS 808 Query: 185 ----------DQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLN 334 +QL Q+ +LE + L +Q+ E E K+ E L Q+ Sbjct: 809 ATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTE----LDAHKIQVQ 864 Query: 335 KLTQNVSK-SAEMEKKVQDL----EQKLQLAYSKSDEQAKDAVV 451 L Q + K ++EME+KV+ L E KL+ +K EQ K +V Sbjct: 865 DLMQQLEKQNSEMEQKVKSLTQVYESKLEDG-NKEQEQTKQILV 907 Score = 33.5 bits (75), Expect = 0.55 Identities = 35/163 (21%), Positives = 71/163 (43%), Gaps = 14/163 (8%) Frame = +2 Query: 92 ELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKHAAELEVQVSALDQQLQEAEI 271 ELEA R + ++ ++ + + QLE + ++ + +L + + + Sbjct: 1273 ELEAQLRQLTEEQNTLNISFQQ-------ATHQLEEKENQIKSMKADIESLVTEKEALQK 1325 Query: 272 HYKNKVAEESEKLALVNTQLNKLTQNVS-----KSAEMEKKVQ---------DLEQKLQL 409 N+ SEK + + +L++N++ K EKKV+ DL +LQ Sbjct: 1326 EGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQN 1385 Query: 410 AYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQAPSTAS 538 + S S+ K+A +S+ +++ + ++ QDLS T S Sbjct: 1386 SISLSE---KEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLS 1425 Score = 33.1 bits (74), Expect = 0.72 Identities = 40/180 (22%), Positives = 78/180 (43%), Gaps = 12/180 (6%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSA 184 E + S ++ L EK+ L++QL E +ELE ++++ A KT Sbjct: 300 ETIQSHKEQCTLLTSEKEALQEQLDERLQELE-------------KIKDLHM-AEKTKLI 345 Query: 185 DQLEVAQKHAAELE----VQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNV 352 QL A+ +LE + ++ +Q+ E + ++A+ ++ + TQ +L + Sbjct: 346 TQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQK 405 Query: 353 SKS-----AEMEKKV---QDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQ 508 KS E+EK + Q E+ + ++ DEQ K ++ SL + K++ Sbjct: 406 EKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQE 465
>MYH10_BOVIN (Q27991) Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle| myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B) Length = 1976 Score = 42.0 bits (97), Expect = 0.002 Identities = 43/190 (22%), Positives = 85/190 (44%), Gaps = 12/190 (6%) Frame = +2 Query: 50 EKDQLEQQLLEVRKELEAAYRTIANQEE-----QASVREIKW---DAYKTYSADQLEVAQ 205 +K L ++L ++ ELE T A Q+E + V E+K + K++ A ++ Q Sbjct: 1140 QKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKSHEAQIQDMRQ 1199 Query: 206 KHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLN---KLTQNVSKSAEMEK 376 +HA LE L +QL++A+ +K + + + L N +L K+ Q V +E ++ Sbjct: 1200 RHATALE----ELSEQLEQAK-RFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKR 1254 Query: 377 KVQDLE-QKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQAPSTASVNPAQ 553 K D + Q+L S+ D + + LD+++ +E + + Sbjct: 1255 KKLDAQVQELHAKVSEGDRLRVELAEKANKLQNELDNVSTLLEEAEKKGIKFAKDAAGLE 1314 Query: 554 QQLREPSGIM 583 QL++ ++ Sbjct: 1315 SQLQDTQELL 1324 Score = 40.0 bits (92), Expect = 0.006 Identities = 44/181 (24%), Positives = 78/181 (43%), Gaps = 7/181 (3%) Frame = +2 Query: 41 LVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKH--- 211 L+ EK +LE ++ ++ +ELE + ++ ++ D T A + AQK Sbjct: 1727 LLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNTELAAERSAAQKSDNA 1786 Query: 212 AAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQL-NKLTQNVSKSAEMEKKVQD 388 +LE Q L +LQE E K+K L QL +L Q + A K V+ Sbjct: 1787 RQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRR 1846 Query: 389 LEQKLQLAYSKSDEQAKDAVVSTRSREFS---LDSLTPQNKEQDLSQAPSTASVNPAQQQ 559 E+KL+ + + +++ + A E + + L Q +E + + AS Q++ Sbjct: 1847 TEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRE 1906 Query: 560 L 562 L Sbjct: 1907 L 1907 Score = 37.0 bits (84), Expect = 0.050 Identities = 45/179 (25%), Positives = 80/179 (44%), Gaps = 3/179 (1%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSA 184 + L +++ + + D QQL KEL+A QE + +V+ K+ A T SA Sbjct: 1767 DTLNTELAAERSAAQKSDNARQQLERQNKELKAKL-----QELEGAVKS-KFKA--TISA 1818 Query: 185 DQLEVAQKHAAELEVQVSALDQQLQE--AEIHYKNKVAEESE-KLALVNTQLNKLTQNVS 355 LE ++ L++QL++ E NK+ +E KL + Q+ ++ Sbjct: 1819 ------------LEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHAD 1866 Query: 356 KSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQAPST 532 + E +K ++L+ +++E+A A S R + LD T N + LS+ ST Sbjct: 1867 QYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEAN--EGLSREVST 1923 Score = 36.2 bits (82), Expect = 0.085 Identities = 47/210 (22%), Positives = 84/210 (40%), Gaps = 21/210 (10%) Frame = +2 Query: 2 NEALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYS 181 ++ L + A E+D+ E + E + + R + EE RE K Sbjct: 1454 DQLLAEEKNISARYAEERDRAEAEAREKETKALSLARAL---EEALEAREEAERQNKQLR 1510 Query: 182 ADQLEVAQ------KHAAELEVQVSALDQQLQE-----AEIHYKNKVAEESEKLALVNTQ 328 AD ++ K+ ELE AL+QQ++E E+ + + E+++ VN Q Sbjct: 1511 ADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQ 1570 Query: 329 LNKL----------TQNVSKSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSL 478 K QN K + K+V++LE +L+ +Q AV S + E L Sbjct: 1571 AMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELE----DERKQRALAVASKKKMEIDL 1626 Query: 479 DSLTPQNKEQDLSQAPSTASVNPAQQQLRE 568 L Q + + ++ + Q Q+++ Sbjct: 1627 KDLEAQIEAANKARDEVIKQLRKLQAQMKD 1656 Score = 35.4 bits (80), Expect = 0.14 Identities = 44/201 (21%), Positives = 88/201 (43%), Gaps = 19/201 (9%) Frame = +2 Query: 11 LTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQ 190 L + ++ NL +++ E + ++ + L+ +T QE + + R++ D T DQ Sbjct: 1015 LAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKT--RQELEKAKRKL--DGETTDLQDQ 1070 Query: 191 LEVAQKHAAELEVQVSALDQQLQEA------EIHYKN-----------KVAEESEKLALV 319 + Q EL++QV+ +++LQ A E +KN ++AE E Sbjct: 1071 IAELQAQIDELKIQVAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESE 1130 Query: 320 NTQLNKL-TQNVSKSAEMEKKVQDLEQKLQLAYSKSDEQAK-DAVVSTRSREFSLDSLTP 493 NK Q S E+E +LE L ++ + + K + V+ + ++ + Sbjct: 1131 KASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKSH 1190 Query: 494 QNKEQDLSQAPSTASVNPAQQ 556 + + QD+ Q +TA ++Q Sbjct: 1191 EAQIQDMRQRHATALEELSEQ 1211 Score = 32.3 bits (72), Expect = 1.2 Identities = 29/144 (20%), Positives = 60/144 (41%) Frame = +2 Query: 50 EKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKHAAELEV 229 + ++ ++ L++ +ELEA Q A + K + Q+E A K E+ Sbjct: 1586 QNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIK 1645 Query: 230 QVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEMEKKVQDLEQKLQL 409 Q+ L Q+++ + + A E A KL ++ ++++++ E+ + Sbjct: 1646 QLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRH 1705 Query: 410 AYSKSDEQAKDAVVSTRSREFSLD 481 A + DE A + S + LD Sbjct: 1706 AEQERDELADEIANSASGKSALLD 1729
>TPM4_MOUSE (Q6IRU2) Tropomyosin alpha-4 chain (Tropomyosin-4)| Length = 247 Score = 42.0 bits (97), Expect = 0.002 Identities = 33/122 (27%), Positives = 55/122 (45%) Frame = +2 Query: 47 HEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKHAAELE 226 H D+ +++ EV ++L + EE+A V E+K LE K+ Sbjct: 116 HITDEADRKYEEVARKLVILEGELKRAEERAEVSELK--------CGDLEEELKNVTNNL 167 Query: 227 VQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEMEKKVQDLEQKLQ 406 + A ++ E E Y+ ++ S+KL T+ + VSK +EK + DLE+KL Sbjct: 168 KSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVSK---LEKTIDDLEEKLA 224 Query: 407 LA 412 A Sbjct: 225 QA 226
>MYH3_RAT (P12847) Myosin heavy chain, fast skeletal muscle, embryonic| Length = 1940 Score = 42.0 bits (97), Expect = 0.002 Identities = 42/180 (23%), Positives = 76/180 (42%), Gaps = 32/180 (17%) Frame = +2 Query: 2 NEALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYS 181 NE + ++ +L+H K +LE L +++ E+E A R N EE+A ++ DA Sbjct: 1711 NERVQLLHTQNTSLIHTKKKLETDLTQLQSEVEDASRDARNAEEKA--KKAITDA--AMM 1766 Query: 182 ADQLEVAQKHAAELE-----------------------------VQVSALDQQLQEAEIH 274 A++L+ Q +A LE Q+ L+ +++E E Sbjct: 1767 AEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEFE 1826 Query: 275 YKNKVAEESEKLALVNTQLNKLTQNVSKSAEMEKKV---QDLEQKLQLAYSKSDEQAKDA 445 + + +E + + ++ + +S E K V QDL KLQ+ QA++A Sbjct: 1827 LEGEQKRNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEEA 1886 Score = 38.9 bits (89), Expect = 0.013 Identities = 48/199 (24%), Positives = 89/199 (44%), Gaps = 10/199 (5%) Frame = +2 Query: 2 NEALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYS 181 N+ E NL+ +++ +Q L++ + +LEA + + + E + A K Sbjct: 886 NDLQLQVQAESENLLDAEERCDQ-LIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKL 944 Query: 182 ADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKS 361 D+ +K +LE+ ++ ++++ E NKV +E+LA ++ + KLT+ Sbjct: 945 EDECSELKKDIDDLELTLAKVEKEKHATE----NKVKNLTEELAGLDETIAKLTREKKAL 1000 Query: 362 AEM-EKKVQDLEQKLQLAYSKSD-----EQAKDAVVSTRSREFSLDSLTPQNK---EQDL 514 E ++ + DL+ + S S EQ D + S+ +E L +NK E DL Sbjct: 1001 QEAHQQTLDDLQAEEDKVNSLSKLKSKLEQQVDDLESSLEQEKKLRVDLERNKRKLEGDL 1060 Query: 515 SQA-PSTASVNPAQQQLRE 568 A S + +QQL E Sbjct: 1061 KLAQESILDLENDKQQLDE 1079 Score = 32.0 bits (71), Expect = 1.6 Identities = 50/217 (23%), Positives = 89/217 (41%), Gaps = 9/217 (4%) Frame = +2 Query: 11 LTSKMQEHANLVHEKD----QLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTY 178 LT E + EKD QL++ + ++ A +A + K + Sbjct: 1566 LTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQGALDAEVRSRNEAIRLKKKMEGDLNE 1625 Query: 179 SADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEE---SEKLALVNTQLNKLTQN 349 QL A + AAE + ++ QL++ ++H + + + E+LA+V + N L Sbjct: 1626 IEIQLSHANRQAAETIKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLL--- 1682 Query: 350 VSKSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSL--TPQNKEQDLSQA 523 AE+E+ LEQ + A ++++ D+ + SL T + E DL+Q Sbjct: 1683 ---QAEVEELRATLEQ-TERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLTQL 1738 Query: 524 PSTASVNPAQQQLREPSGIMAFKFILGVALLVSSLRR 634 S V A + R A K I A++ L++ Sbjct: 1739 QS--EVEDASRDARNAEE-KAKKAITDAAMMAEELKK 1772
>MYH2_HUMAN (Q9UKX2) Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy| chain IIa) (MyHC-IIa) Length = 1941 Score = 42.0 bits (97), Expect = 0.002 Identities = 48/207 (23%), Positives = 86/207 (41%), Gaps = 19/207 (9%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKW-------- 160 E + ++ A ++ L ++L E+ + LE A + Q E RE ++ Sbjct: 1126 EEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLE 1185 Query: 161 DAYKTYSADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKL 340 +A + A + +KHA V+ L +Q+ + K K+ +E ++ + L Sbjct: 1186 EATLQHEATAATLRKKHADS----VAELGEQIDNLQ-RVKQKLEKEKSEMKMEIDDLASN 1240 Query: 341 TQNVSKS-AEMEKKVQDLEQKLQLAYSKSDEQ--------AKDAVVSTRSREFS--LDSL 487 + VSK+ +EK + LE +L SK +EQ A+ + T S EFS LD Sbjct: 1241 VETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEK 1300 Query: 488 TPQNKEQDLSQAPSTASVNPAQQQLRE 568 + + T + ++QL E Sbjct: 1301 EALVSQLSRGKQAFTQQIEELKRQLEE 1327 Score = 34.7 bits (78), Expect = 0.25 Identities = 46/217 (21%), Positives = 91/217 (41%), Gaps = 37/217 (17%) Frame = +2 Query: 29 EHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQK 208 ++ +L++ K +LE + +++ E+E + N EE+A ++ DA A++L+ Q Sbjct: 1725 QNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKA--KKAITDA--AMMAEELKKEQD 1780 Query: 209 HAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVN--TQLNKLTQNV---------- 352 +A LE ++Q +++ ++ +E+E+LAL Q+ KL V Sbjct: 1781 TSAHLERMKKNMEQTVKDLQLRL-----DEAEQLALKGGKKQIQKLEARVRELEGEVESE 1835 Query: 353 -SKSAEMEK------------------------KVQDLEQKLQLAYSKSDEQAKDAVVST 457 ++AE K ++QDL KLQ QA++A + Sbjct: 1836 QKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQS 1895 Query: 458 RSREFSLDSLTPQNKEQDLSQAPSTASVNPAQQQLRE 568 + L + +E + + + VN + + RE Sbjct: 1896 NTNLAKFRKLQHELEEAEERADIAESQVNKLRVKSRE 1932
>ROCK2_MOUSE (P70336) Rho-associated protein kinase 2 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 2) (p164 ROCK-2) Length = 1388 Score = 42.0 bits (97), Expect = 0.002 Identities = 42/186 (22%), Positives = 88/186 (47%), Gaps = 7/186 (3%) Frame = +2 Query: 26 QEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQ 205 QE+ +L+ K LE+Q E+RKE + A + ++Q + YKT +L+ Sbjct: 829 QENNHLMEMKMNLEKQNTELRKERQDADGQMKELQDQLEAEQYFSTLYKT-QVRELKEEN 887 Query: 206 KHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSK----SAEME 373 + +L ++ Q LQ+ ++ +A + E + L +L +++++ E E Sbjct: 888 EEKTKLCKELQQKKQDLQDE----RDSLAAQLE-ITLTKADSEQLARSIAEEQYSDLEKE 942 Query: 374 KKVQDLEQKLQLAYSKSDEQAKDAVVST---RSREFSLDSLTPQNKEQDLSQAPSTASVN 544 K +++LE K +A K + KD +++ +R + D N++++L+ + Sbjct: 943 KIMKELEIKEMMARHKQELTEKDTTIASLEETNRTLTSDVANLANEKEELNN-----KLK 997 Query: 545 PAQQQL 562 +Q+QL Sbjct: 998 DSQEQL 1003
>GOGA3_MOUSE (P55937) Golgin subfamily A member 3 (Golgin-160) (Male-enhanced| antigen 2) (MEA-2) Length = 1487 Score = 41.6 bits (96), Expect = 0.002 Identities = 31/169 (18%), Positives = 74/169 (43%) Frame = +2 Query: 53 KDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKHAAELEVQ 232 KDQL +L +K L++ + + + + + + + + + + AELE Sbjct: 858 KDQLINELKATKKRLDSEMKELRQELIKLQGEKKTVEVEHSRLQKDMSLVHQQMAELEGH 917 Query: 233 VSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEMEKKVQDLEQKLQLA 412 + ++ ++ E EIH ++ ++ + +AL Q E +K + + +QK++ Sbjct: 918 LQSVQKERDEMEIHLQSLKFDKEQMIALTEANETLKKQIEELQQEAKKAITEQKQKMKRL 977 Query: 413 YSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQAPSTASVNPAQQQ 559 S K+ ++ E ++ L+ + +E S+ + A +N + Q Sbjct: 978 GSDLTSAQKEMKTKHKAYENAVSILSRRLQEALASKEATDAELNQLRAQ 1026 Score = 38.5 bits (88), Expect = 0.017 Identities = 38/194 (19%), Positives = 90/194 (46%), Gaps = 1/194 (0%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSA 184 EAL +K Q +L D+L+ +L E+++E ++ I + + V E+ + K+ Sbjct: 727 EALQAKGQSLDDLHTRYDELQARLEELQREADSREDAIHFLQNEKIVLEVALQSAKS-DK 785 Query: 185 DQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSA 364 ++L+ + E + S L +QL++ N+V ++ A + Q+ K+ Sbjct: 786 EELDRGARRLEEDTEETSGLLEQLRQDLAVKSNQVEHLQQETATLRKQMQKV-------- 837 Query: 365 EMEKKVQDLEQKLQLAYSKSDEQAKDAVVS-TRSREFSLDSLTPQNKEQDLSQAPSTASV 541 K Q ++QK+ + + D +KD +++ ++ + LDS + +++ + +V Sbjct: 838 ----KEQFVQQKVMVEAYRRDATSKDQLINELKATKKRLDSEMKELRQELIKLQGEKKTV 893 Query: 542 NPAQQQLREPSGIM 583 +L++ ++ Sbjct: 894 EVEHSRLQKDMSLV 907 Score = 29.6 bits (65), Expect = 7.9 Identities = 35/184 (19%), Positives = 86/184 (46%), Gaps = 9/184 (4%) Frame = +2 Query: 41 LVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVA--QKHA 214 ++ K++ ++Q+ ++ + L+ ++ ++E+ V +K + +A ++E ++H Sbjct: 1155 VLQRKEEEDRQMKQLVQALQ-----VSLEKEKMEVNSLK----EQMAAARIEAGHNRRHF 1205 Query: 215 AELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEMEKKVQDLE 394 +++S + ++LQ E H + E ++L + Q K +Q + A+ + ++ + Sbjct: 1206 KAATLELSEVKKELQAKE-HLVQTLQAEVDELQI---QDGKHSQEI---AQFQTELAEAR 1258 Query: 395 QKLQLAYSKSDEQAKDAVVSTRSRE---FSLD----SLTPQNKEQDLSQAPSTASVNPAQ 553 +LQL K DEQ ++ E + LD + ++ DL++ + Q Sbjct: 1259 TQLQLLQKKLDEQMSQQPTGSQEMEDLKWELDQKEREIQSLKQQLDLTEQQGKKELEGTQ 1318 Query: 554 QQLR 565 Q L+ Sbjct: 1319 QTLQ 1322
>CLPB_LISMF (Q71XF9) Chaperone clpB| Length = 866 Score = 41.6 bits (96), Expect = 0.002 Identities = 36/123 (29%), Positives = 66/123 (53%), Gaps = 3/123 (2%) Frame = +2 Query: 29 EHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQK 208 E A L EKD ++ LE+ + R +A+ +E+A+ + KW++ K E+++ Sbjct: 427 EEAALKEEKDPASERRLEILQ------RELADYKEEANQMKSKWESEKN------EISK- 473 Query: 209 HAAELEVQVSALDQQLQEAEIHYK-NKVAE-ESEKLALVNTQLNKL-TQNVSKSAEMEKK 379 E+ Q+ L +L+EAE +Y NK AE K+ V +L +L +N K+A+ ++ Sbjct: 474 -IREVREQIDHLRHELEEAENNYDLNKAAELRHGKIPAVEKELLELEAENREKTAQEDRI 532 Query: 380 VQD 388 +Q+ Sbjct: 533 LQE 535
>USO1_YEAST (P25386) Intracellular protein transport protein USO1 (Int-1)| Length = 1790 Score = 41.6 bits (96), Expect = 0.002 Identities = 47/187 (25%), Positives = 86/187 (45%), Gaps = 15/187 (8%) Frame = +2 Query: 53 KDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVA--QKHAAELE 226 KD+ E Q+ ++++LE A T AN E + E+ KT + E+A + ELE Sbjct: 1049 KDEYESQISLLKEKLETA--TTANDENVNKISELT----KTREELEAELAAYKNLKNELE 1102 Query: 227 VQVSALDQQLQEA---EIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEMEKKVQDLEQ 397 ++ ++ L+E E H K + + ++ QLN L N+ +EK+ +DL Sbjct: 1103 TKLETSEKALKEVKENEEHLKEEKIQLEKEATETKQQLNSLRANLE---SLEKEHEDLAA 1159 Query: 398 KL-----QLA-----YSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQAPSTASVNP 547 +L Q+A Y++ Q D + ST+ +S+ +N E + + + S + Sbjct: 1160 QLKKYEEQIANKERQYNEEISQLNDEITSTQQEN---ESIKKKNDELE-GEVKAMKSTSE 1215 Query: 548 AQQQLRE 568 Q L++ Sbjct: 1216 EQSNLKK 1222 Score = 39.7 bits (91), Expect = 0.008 Identities = 52/220 (23%), Positives = 94/220 (42%), Gaps = 35/220 (15%) Frame = +2 Query: 14 TSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQL 193 T Q+ +L + LE++ ++ +L+ IAN+E Q + + + T + + Sbjct: 1134 TETKQQLNSLRANLESLEKEHEDLAAQLKKYEEQIANKERQYNEEISQLNDEITSTQQEN 1193 Query: 194 EVAQKHAAELEVQVSALDQ----------------QLQEAEIHYKNKVAEES--EKLALV 319 E +K ELE +V A+ LQ E+ KN+ E S E + V Sbjct: 1194 ESIKKKNDELEGEVKAMKSTSEEQSNLKKSEIDALNLQIKELKKKNETNEASLLESIKSV 1253 Query: 320 NTQLNKLTQNVSKSAEMEKKVQDLEQKLQ---------LAYSKSDEQAKDAV-VSTRSRE 469 ++ K+ + + EK+V +LE KL+ L K E+ K+ + T + Sbjct: 1254 ESETVKIKELQDECNFKEKEVSELEDKLKASEDKNSKYLELQKESEKIKEELDAKTTELK 1313 Query: 470 FSLDSLTPQNK-----EQDLSQAPSTASV--NPAQQQLRE 568 L+ +T +K E +LS+ T+S A++QL + Sbjct: 1314 IQLEKITNLSKAKEKSESELSRLKKTSSEERKNAEEQLEK 1353 Score = 38.1 bits (87), Expect = 0.022 Identities = 32/168 (19%), Positives = 69/168 (41%) Frame = +2 Query: 2 NEALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYS 181 NE L + NL EK+ + ++L+E + ++ +A E+ + + + Sbjct: 919 NENLEEMKIQCNNLSKEKEHISKELVEYKSRFQSHDNLVAKLTEKLKSLANNYKDMQAEN 978 Query: 182 ADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKS 361 ++ ++ E +Q+S L +NK+ S++ + + +N+ Sbjct: 979 ESLIKAVEESKNESSIQLSNL-----------QNKIDSMSQEKENFQIERGSIEKNIE-- 1025 Query: 362 AEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKE 505 +++K + DLEQ + SKSD + + L++ T N E Sbjct: 1026 -QLKKTISDLEQTKEEIISKSDSSKDEYESQISLLKEKLETATTANDE 1072 Score = 36.2 bits (82), Expect = 0.085 Identities = 40/164 (24%), Positives = 71/164 (43%), Gaps = 11/164 (6%) Frame = +2 Query: 11 LTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQ--ASVREIKWD------- 163 L K E + EK+ L +L E+ +EL++ + EE+ A VR+ + + Sbjct: 1619 LKDKQAEIKSNQEEKELLTSRLKELEQELDSTQQKAQKSEEERRAEVRKFQVEKSQLDEK 1678 Query: 164 --AYKTYSADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNK 337 +T D + Q + + D Q QE E K+A+E + L N++L + Sbjct: 1679 AMLLETKYNDLVNKEQAWKRDEDTVKKTTDSQRQEIE-----KLAKELDNLKAENSKLKE 1733 Query: 338 LTQNVSKSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSRE 469 ++ S+ ++ V DL++K +K + KD V S E Sbjct: 1734 ANEDRSEIDDLMLLVTDLDEK----NAKYRSKLKDLGVEISSDE 1773 Score = 35.8 bits (81), Expect = 0.11 Identities = 42/191 (21%), Positives = 75/191 (39%), Gaps = 13/191 (6%) Frame = +2 Query: 2 NEALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYS 181 NE ++ QE++ ++ LE +L+ ++ E E + I N + Sbjct: 1373 NEGSSTITQEYSEKINT---LEDELIRLQNENELKAKEIDN------------------T 1411 Query: 182 ADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALV-----------NTQ 328 +LE EL + + LQ+ + YK+K+ EKL + Q Sbjct: 1412 RSELEKVSLSNDELLEEKQNTIKSLQDEILSYKDKITRNDEKLLSIERDNKRDLESLKEQ 1471 Query: 329 LNKLTQNVSKSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSL--TPQNK 502 L ++ +K E KK+++ K + KS E K + S E L S T + Sbjct: 1472 LRAAQESKAKVEEGLKKLEEESSKEKAELEKSKEMMKKLESTIESNETELKSSMETIRKS 1531 Query: 503 EQDLSQAPSTA 535 ++ L Q+ +A Sbjct: 1532 DEKLEQSKKSA 1542
>MYSP_BRUMA (Q01202) Paramyosin| Length = 880 Score = 41.2 bits (95), Expect = 0.003 Identities = 44/202 (21%), Positives = 87/202 (43%), Gaps = 14/202 (6%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSA 184 E ++ E +N V + ++ L + R+ L+A + + V+ K A Sbjct: 182 ERFEAQTVELSNKVEDLNRHVNDLAQQRQRLQAENNDLLKEIHDQKVQLDNLQHVKYQLA 241 Query: 185 DQLEVAQKHAAELEVQVSALDQQLQEAEIHYKN----------KVAEESEKLALVNTQLN 334 QLE A++ + E + S L QL + ++ + AE KLAL NT++ Sbjct: 242 QQLEEARRRLEDAERERSQLQAQLHQVQLELDSVRTALDEESAARAEAEHKLALANTEIT 301 Query: 335 KLTQNVSKSAEM-EKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKE-- 505 + + ++V+DL +K+ ++ +EQ + + E + L + + Sbjct: 302 QWKSKFDAEVALHHEEVEDLRKKMLQKQAEYEEQIEIMLQKISQLEKAKSRLQSEVEVLI 361 Query: 506 QDLSQAPST-ASVNPAQQQLRE 568 DL +A +T A + A++QL + Sbjct: 362 VDLEKAQNTIAILERAKEQLEK 383
>P115_MYCHR (P41508) Protein P115| Length = 979 Score = 41.2 bits (95), Expect = 0.003 Identities = 41/145 (28%), Positives = 65/145 (44%), Gaps = 13/145 (8%) Frame = +2 Query: 128 EEQASVREIKWDAYKTYSA-----DQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVA 292 EE A + K D + D ++ Q ELE QV++LD+Q +A+I+ + A Sbjct: 163 EEAAGTSKYKLDKEEAQKKLIRTNDAIDKLQGAIKELERQVNSLDKQASKAKIYLEKSKA 222 Query: 293 EESEKLALVNTQLN----KLTQNVSKSAEMEKKVQDLEQKLQLAYSKSDEQA----KDAV 448 ES ++ L+ LN KL + E+E++ DLE +Q Y S Q + Sbjct: 223 LESVEVGLIVNDLNFFNEKLNNLNTSLLEVEQQRNDLELNIQ-TYESSISQTVHFKTEVE 281 Query: 449 VSTRSREFSLDSLTPQNKEQDLSQA 523 S + LD+L E +L +A Sbjct: 282 SSIQEITSKLDNLKNALSEINLQEA 306
>MD1L1_CRIGR (Q80YF0) Mitotic spindle assembly checkpoint protein MAD1 (Mitotic| arrest deficient-like protein 1) (MAD1-like 1) Length = 717 Score = 41.2 bits (95), Expect = 0.003 Identities = 37/149 (24%), Positives = 66/149 (44%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSA 184 E + +++ H D QQL E L AA TI++ + + S ++ Sbjct: 122 EKMQEQLERHRLCKQSLDAASQQLREREDGLAAARETISSLKGRVSEMQL---------- 171 Query: 185 DQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSA 364 +A + +VQV L+ + QE K ++ + K + ++ +L + + A Sbjct: 172 --------NAMDQKVQVKRLESEKQEL----KEQLELQQRKCQEASQKIQELQASQEERA 219 Query: 365 EMEKKVQDLEQKLQLAYSKSDEQAKDAVV 451 + E+K++DLEQKL L Q +DA V Sbjct: 220 DHEQKIKDLEQKLCL-------QEQDAAV 241 Score = 35.0 bits (79), Expect = 0.19 Identities = 43/167 (25%), Positives = 74/167 (44%), Gaps = 10/167 (5%) Frame = +2 Query: 50 EKDQLEQQLLEVRKELEAAYRTIA---------NQEEQASVREIKWDAYKTYSADQLEVA 202 EK Q+E R ELE A T A NQE A +R+++ + + ++++ Sbjct: 70 EKMQMELSHKRARVELERAANTSARNYEREVDRNQELLARIRQLQ--EREAAAEEKMQEQ 127 Query: 203 QKHAAELEVQVSALDQQLQEAEIHY-KNKVAEESEKLALVNTQLNKLTQNVSKSAEMEKK 379 + + + A QQL+E E + S K + QLN + Q V + +E + Sbjct: 128 LERHRLCKQSLDAASQQLREREDGLAAARETISSLKGRVSEMQLNAMDQKV-QVKRLESE 186 Query: 380 VQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQ 520 Q+L+++L+L K E ++ S+E D + K +DL Q Sbjct: 187 KQELKEQLELQQRKCQEASQKIQELQASQEERADH---EQKIKDLEQ 230
>LIPA2_HUMAN (O75334) Liprin-alpha-2 (Protein tyrosine phosphatase receptor type| f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2) Length = 1257 Score = 41.2 bits (95), Expect = 0.003 Identities = 40/143 (27%), Positives = 62/143 (43%), Gaps = 6/143 (4%) Frame = +2 Query: 8 ALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSAD 187 ALT + H N+ LE QL E +EL+ A + EE D T S + Sbjct: 419 ALTKAEETHGNIEERMRHLEGQLEEKNQELQRARQREKMNEEHNKRLSDTVDRLLTESNE 478 Query: 188 QLEV-AQKHAAELE-----VQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQN 349 +L++ ++ A LE +Q S ++ E +H K +AEE EKL ++L++L Sbjct: 479 RLQLHLKERMAALEEKNVLIQESETFRKNLEESLHDKESLAEEIEKL---RSELDQLKMR 535 Query: 350 VSKSAEMEKKVQDLEQKLQLAYS 418 E L+ +L YS Sbjct: 536 TGSLIEPTIPRTHLDTSAELRYS 558
>TPM1_BIOGL (P42636) Tropomyosin 1 (TMI) (Bg 39)| Length = 284 Score = 41.2 bits (95), Expect = 0.003 Identities = 39/162 (24%), Positives = 75/162 (46%), Gaps = 17/162 (10%) Frame = +2 Query: 5 EALTSKM----QEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYK 172 +A+ KM E N + +Q+EQ+L +V + N + + S + +D Sbjct: 2 DAIKKKMLAMKMEKENAIDRAEQMEQKLRDVEETKNKLEEEFNNLQNKFSNLQNDFDTAN 61 Query: 173 ---TYSADQLEVAQKHAAELEVQVSALDQQLQ---------EAEIHYKNKVAEESEKLAL 316 T + +LE ++KH AELE + L++++Q E + + EE+ K A Sbjct: 62 EGLTEAQTKLEASEKHVAELESDTAGLNRRIQLLEEDLERSEERLQSATEKLEEASKAAD 121 Query: 317 VNTQLNKLTQNVSKSAEMEKKVQDLEQKLQLA-YSKSDEQAK 439 + + K+ + S+S ++++ LE +L+ A Y D + K Sbjct: 122 ESERGRKVLE--SRSLADDERLDGLEAQLKEAKYIAEDAERK 161
>MRCKA_HUMAN (Q5VT25) Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1)| (CDC42-binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) (DMPK-like alpha Length = 1732 Score = 41.2 bits (95), Expect = 0.003 Identities = 43/198 (21%), Positives = 93/198 (46%), Gaps = 29/198 (14%) Frame = +2 Query: 50 EKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSA--DQLEVAQKHAAEL 223 E L++++ ++RK++ + EE +VR+ DA++ A Q++ Q+ +L Sbjct: 488 EIKNLKEEIEKLRKQVTESSHLEQQLEEANAVRQELDDAFRQIKAYEKQIKTLQQEREDL 547 Query: 224 EVQVSALDQQLQE-----AEIHYKNKVA-----EESEKLALVNTQLNKLTQNVSKSAE-- 367 ++ ++L+ + H + K+A E +E+L ++TQ KL ++V E Sbjct: 548 NKELVQASERLKNQSKELKDAHCQRKLAMQEFMEINERLTELHTQKQKLARHVRDKEEEV 607 Query: 368 --MEKKVQDLEQKLQL-----------AYSKSDEQAKDAVVSTRSREFS--LDSLTPQNK 502 + +KV+ L Q+L+ + + E +KD + +S +S L++ K Sbjct: 608 DLVMQKVESLRQELRRTERAKKELEVHTEALAAEASKDRKLREQSEHYSKQLENELEGLK 667 Query: 503 EQDLSQAPSTASVNPAQQ 556 ++ +S +P S+ Q+ Sbjct: 668 QKQISYSPGVCSIEHQQE 685 Score = 36.2 bits (82), Expect = 0.085 Identities = 27/120 (22%), Positives = 55/120 (45%), Gaps = 6/120 (5%) Frame = +2 Query: 59 QLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKHAAELEVQVS 238 ++ ++L E+ + + R + ++EE+ + K ++ + +L ++ ELEV Sbjct: 581 EINERLTELHTQKQKLARHVRDKEEEVDLVMQKVESLR----QELRRTERAKKELEVHTE 636 Query: 239 AL------DQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEMEKKVQDLEQK 400 AL D++L+E HY ++ E E L + ++ E+ K DLE+K Sbjct: 637 ALAAEASKDRKLREQSEHYSKQLENELEGLKQKQISYSPGVCSIEHQQEITKLKTDLEKK 696
>TPM4_RAT (P09495) Tropomyosin alpha-4 chain (Tropomyosin-4) (TM-4)| Length = 247 Score = 41.2 bits (95), Expect = 0.003 Identities = 32/122 (26%), Positives = 56/122 (45%) Frame = +2 Query: 47 HEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKHAAELE 226 H ++ +++ EV ++L + EE+A V E+K + LE K+ Sbjct: 116 HIAEEADRKYEEVARKLVILEGELERAEERAEVSELK--------SSDLEEELKNVTNNL 167 Query: 227 VQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEMEKKVQDLEQKLQ 406 + A ++ E E Y+ ++ S+KL T+ + VSK +EK + DLE+KL Sbjct: 168 KSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVSK---LEKTIDDLEEKLA 224 Query: 407 LA 412 A Sbjct: 225 QA 226
>MYSS_CHICK (P13538) Myosin heavy chain, skeletal muscle, adult| Length = 1938 Score = 41.2 bits (95), Expect = 0.003 Identities = 51/213 (23%), Positives = 92/213 (43%), Gaps = 38/213 (17%) Frame = +2 Query: 29 EHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQK 208 ++ +L++ K +LE +++++ E+E + N EE+A ++ DA A++L+ Q Sbjct: 1721 QNTSLINTKKKLETDIVQIQSEMEDTIQEARNAEEKA--KKAITDA--AMMAEELKKEQD 1776 Query: 209 HAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVN--TQLNKLTQNV---------- 352 +A LE +DQ +++ + +E+E+LAL QL KL V Sbjct: 1777 TSAHLERMKKNMDQTVKDLHVRL-----DEAEQLALKGGKKQLQKLEARVRELEGEVDSE 1831 Query: 353 -SKSAEMEK------------------------KVQDLEQKLQLAYSKSDEQAKDAVVST 457 +SAE K ++QDL KLQ+ QA++A Sbjct: 1832 QKRSAEAVKGVRKYERRVKELTYQCEEDRKNILRLQDLVDKLQMKVKSYKRQAEEA---- 1887 Query: 458 RSREFSLDSLTPQNK-EQDLSQAPSTASVNPAQ 553 E S +L+ K + +L +A A + +Q Sbjct: 1888 --EELSNVNLSKFRKIQHELEEAEERADIAESQ 1918 Score = 40.0 bits (92), Expect = 0.006 Identities = 43/196 (21%), Positives = 89/196 (45%), Gaps = 10/196 (5%) Frame = +2 Query: 11 LTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQ 190 L ++Q A+ + + ++ QL++ + +LEA + + + E + A K D+ Sbjct: 889 LQLQVQAEADSLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDE 948 Query: 191 LEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEM 370 +K +LE+ ++ ++++ E NKV +E++A+++ + KLT+ E Sbjct: 949 CSELKKDIDDLELTLAKVEKEKHATE----NKVKNLTEEMAVLDETIAKLTKEKKALQEA 1004 Query: 371 EKKV-------QDLEQKLQLAYSKSDEQAKDAVVS-TRSREFSLDSLTPQNK-EQDLSQA 523 ++ +D L A +K ++Q D S + ++ +D + K E DL A Sbjct: 1005 HQQTLDDLQVEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLA 1064 Query: 524 -PSTASVNPAQQQLRE 568 S + +QQL E Sbjct: 1065 HDSIMDLENDKQQLDE 1080 Score = 36.2 bits (82), Expect = 0.085 Identities = 45/188 (23%), Positives = 78/188 (41%), Gaps = 16/188 (8%) Frame = +2 Query: 2 NEALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWD-AYKTY 178 NEAL K + +L +++E QL + A + + N + +I D A +T Sbjct: 1611 NEALRLKKKMEGDL----NEMEIQLSHANRMAAEAQKNLRNTQGTLKDTQIHLDDALRTQ 1666 Query: 179 S--ADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEE-------------SEKLA 313 +Q+ + ++ A L+ +V L L++ E KVAE+ ++ + Sbjct: 1667 EDLKEQVAMVERRANLLQAEVEELRGALEQTE--RSRKVAEQELLDATERVQLLHTQNTS 1724 Query: 314 LVNTQLNKLTQNVSKSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTP 493 L+NT+ T V +EME +Q+ ++E+AK A+ L Sbjct: 1725 LINTKKKLETDIVQIQSEMEDTIQEAR--------NAEEKAKKAITDAAMMAEEL----- 1771 Query: 494 QNKEQDLS 517 KEQD S Sbjct: 1772 -KKEQDTS 1778
>MYSP_MYTGA (O96064) Paramyosin| Length = 864 Score = 41.2 bits (95), Expect = 0.003 Identities = 35/184 (19%), Positives = 84/184 (45%), Gaps = 5/184 (2%) Frame = +2 Query: 26 QEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQ 205 +++ANL E L+ L E EL+AA RTI + + + + +A + A L + Sbjct: 418 EKNANLERENAGLQNALREANNELKAANRTI----NELTALKAQLEAERDNLASALRDTE 473 Query: 206 KHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKS-AEMEKKV 382 + + E +++A L + + ++ E+ E++ + + + ++ E+E + Sbjct: 474 EALRDAEAKLAAAQAALNQLRSEMEQRLREKDEEIDSIRKSSARAIDELQRTLVEVETRY 533 Query: 383 QDLEQKLQLAYSKSDEQAKDAV--VSTRSREF--SLDSLTPQNKEQDLSQAPSTASVNPA 550 + +++ Y + + A+ + + E+ + SL +N+E +L +T ++ Sbjct: 534 KTEISRIKKKYETDIRELEGALDNANRANAEYLKQIKSLQNRNRELELQLEEATRQLDDT 593 Query: 551 QQQL 562 + QL Sbjct: 594 RNQL 597 Score = 31.6 bits (70), Expect = 2.1 Identities = 39/187 (20%), Positives = 78/187 (41%), Gaps = 10/187 (5%) Frame = +2 Query: 11 LTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQ 190 LT + L ++K ++E + ++ +L+ A N + A R + A AD+ Sbjct: 639 LTEVQLQVTALTNDKRRMEADIAAMQSDLDDAL----NGQRAAEERADRLQAEVNRLADE 694 Query: 191 LEVAQKH-------AAELEVQVSALDQQLQEAEIHYKNKVAEESEKL-ALVNTQLNKLTQ 346 L Q + +LE+++ + +L+EAE + + + KL A + N+L Sbjct: 695 LRQEQDNYKNAESLRKQLEIEIREITVRLEEAEAFAQREGKRQIAKLQARIRDLENELEA 754 Query: 347 NVSKSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNK--EQDLSQ 520 + + E + E++ + SDE + T D LT + K ++ + + Sbjct: 755 DQRRLREAAASARKFERQWKETVQASDEDRRQVAELTS----ITDQLTMKCKTYKRMIEE 810 Query: 521 APSTASV 541 A AS+ Sbjct: 811 AEDVASI 817
>MYOJ_DICDI (P54697) Myosin IJ heavy chain| Length = 2245 Score = 41.2 bits (95), Expect = 0.003 Identities = 50/233 (21%), Positives = 98/233 (42%), Gaps = 51/233 (21%) Frame = +2 Query: 14 TSKMQEHANL------VHEKDQL------EQQLLEVRKELEAAYRTIANQEEQASVREIK 157 TSK Q+ N+ + DQL EQ+ +++ +L ++ + Q E + + Sbjct: 1545 TSKQQDQFNMEIQSLRITNNDQLKSLQDYEQEKKKLKDKLSSSKQEAQQQRESIIKMDAE 1604 Query: 158 WDAYKTYSA--------------DQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAE 295 A K +S + +E + + +L Q S +D ++E E N++++ Sbjct: 1605 LSAIKQHSQWVENSFTDMKQRNQELIESSALYKQQLLQQTSTIDSTIKEKE----NEISK 1660 Query: 296 ESEKLALVNTQLNKLTQNVS--------KSAEMEKKVQDLEQKLQLAYSKSDEQAK---D 442 ++L N QL++L + ++ +S E K++ L Q+ Q S ++E +K D Sbjct: 1661 LQQQLETSNQQLHQLKEELNSMKQSNQLESTEQSKQLNQLIQENQQLKSVTNEISKQLDD 1720 Query: 443 AV--------------VSTRSREFSLDSLTPQNKEQDLSQAPSTASVNPAQQQ 559 AV + ++ L + K+Q++ Q ST + QQQ Sbjct: 1721 AVFENQKINNTIKEQEIKSKRMSVELQQHIDEGKQQEIQQLQSTIAQLKQQQQ 1773 Score = 34.7 bits (78), Expect = 0.25 Identities = 48/203 (23%), Positives = 92/203 (45%), Gaps = 20/203 (9%) Frame = +2 Query: 14 TSKMQEHANLVHEKDQLEQQLLEVRKEL-EAAYRTIANQEE---QASVREIKWDAYKTYS 181 +S+ Q A L EK QLEQ + E ++L + + + ++EE Q + E++ +K+ Sbjct: 1194 SSQFQSGAAL--EKQQLEQLVQEQSEQLIKLSSEKLGSEEEAKKQINQLELELTDHKSKL 1251 Query: 182 ADQLEVAQ-------KHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQL--- 331 QL++ + K +LE Q QE E ++K + E EK +L+ TQL Sbjct: 1252 QIQLQLTEQSNEKIKKLKGKLEEYQDEKKQLQQELERIKQSKQSVEDEKNSLI-TQLTTV 1310 Query: 332 ----NKLTQNVSKSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQ- 496 +++ NVS E ++ ++L + K + K+ R +F L+ Q Sbjct: 1311 KFESTQVSTNVSHQKEKITTLKSTIEELNKSIGKLQAEQKNKDDEIRKIQFELNDQKQQF 1370 Query: 497 -NKEQDLSQAPSTASVNPAQQQL 562 + ++ S S S++ + ++ Sbjct: 1371 TRQTKEFSDLQSQQSIDRPKSEI 1393
>RBCC1_HUMAN (Q8TDY2) RB1-inducible coiled-coil protein 1| Length = 1594 Score = 41.2 bits (95), Expect = 0.003 Identities = 41/163 (25%), Positives = 68/163 (41%), Gaps = 20/163 (12%) Frame = +2 Query: 53 KDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQL--EVAQKHAAELE 226 K LEQ+ +R E+ + I + E V + T DQ E+ +H E Sbjct: 1090 KSLLEQETENLRTEISKLNQKIQDNNENYQVGLAELRTLMTIEKDQCISELISRHEEESN 1149 Query: 227 V------QVSALDQQLQEAEIHYKNKVAE-----ESEKLALVNTQLNKLTQNVSKSAEME 373 + +V++L Q E E + K ++ E +SE AL + K+TQ K + Sbjct: 1150 ILKAELNKVTSLHNQAFEIEKNLKEQIIELQSKLDSELSALERQKDEKITQQEEKYEAII 1209 Query: 374 KKVQDLEQKLQLAYSKSDEQ-------AKDAVVSTRSREFSLD 481 + ++ QKL + + EQ KD + T +EF L+ Sbjct: 1210 QNLEKDRQKLVSSQEQDREQLIQKLNCEKDEAIQTALKEFKLE 1252
>MYO1_YEAST (P08964) Myosin-1 (Type II myosin)| Length = 1928 Score = 41.2 bits (95), Expect = 0.003 Identities = 31/130 (23%), Positives = 65/130 (50%), Gaps = 2/130 (1%) Frame = +2 Query: 38 NLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKHAA 217 +LV EKD++ ++ LEV + LE A++ I Q Q ++RE + K +S + + Q Sbjct: 935 DLVSEKDEISREKLEVAQNLEEAHQKI--QGLQETIREREATLEKLHSKNNELIKQISDL 992 Query: 218 ELEVQVSALDQQL-QEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAE-MEKKVQDL 391 ++ Q L +E+++ +N++ + + ++ +S S E ++ K+ L Sbjct: 993 NCDISKEQSSQSLIKESKLKLENEIKRLKDVINSKEEEIKSFNDKLSSSEEDLDIKLVTL 1052 Query: 392 EQKLQLAYSK 421 E+ +A S+ Sbjct: 1053 EKNCNIAMSR 1062
>MYH11_HUMAN (P35749) Myosin-11 (Myosin heavy chain, smooth muscle isoform)| (SMMHC) Length = 1972 Score = 41.2 bits (95), Expect = 0.003 Identities = 47/199 (23%), Positives = 83/199 (41%), Gaps = 11/199 (5%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYK---- 172 E L S+ +K L ++L ++ ELE + A Q+E + RE + K Sbjct: 1125 EDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALD 1184 Query: 173 ----TYSADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVN--TQLN 334 ++ A E+ QKHA +E L+Q + KNK E E L L Sbjct: 1185 EETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLG 1244 Query: 335 KLTQNVS-KSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQD 511 + Q V K ++E +VQ+L+ K ++ + D V ++ S+ + + + + Sbjct: 1245 QAKQEVEHKKKKLEAQVQELQSKCSDG-ERARAELNDKVHKLQNEVESVTGMLNEAEGKA 1303 Query: 512 LSQAPSTASVNPAQQQLRE 568 + A AS++ Q +E Sbjct: 1304 IKLAKDVASLSSQLQDTQE 1322 Score = 39.3 bits (90), Expect = 0.010 Identities = 39/189 (20%), Positives = 85/189 (44%), Gaps = 3/189 (1%) Frame = +2 Query: 11 LTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQ 190 L + ++ NL K++ E + E+ L+ ++ QE + R+++ DA + +Q Sbjct: 1015 LAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKS--RQELEKLKRKLEGDASDFH--EQ 1070 Query: 191 LEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEM 370 + Q AEL++Q++ +++LQ A +++A+++ L K E+ Sbjct: 1071 IADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNAL--------------KKIREL 1116 Query: 371 EKKVQDLEQKL---QLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQAPSTASV 541 E + DL++ L + A +K+++Q +D + + L+ Q +A V Sbjct: 1117 EGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEV 1176 Query: 542 NPAQQQLRE 568 ++ L E Sbjct: 1177 TVLKKALDE 1185 Score = 34.7 bits (78), Expect = 0.25 Identities = 35/177 (19%), Positives = 79/177 (44%), Gaps = 7/177 (3%) Frame = +2 Query: 11 LTSKMQEHANLVHEKDQL-------EQQLLEVRKELEAAYRTIANQEEQASVREIKWDAY 169 L ++Q L E +++ +Q+L E+ E+EA ++ +Q K Sbjct: 892 LQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQ 951 Query: 170 KTYSADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQN 349 +QLE + A Q+LQ ++ + K+ + +++ +++ Q NKL++ Sbjct: 952 MLDLEEQLE-----------EEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSK- 999 Query: 350 VSKSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQ 520 + +E+++ DL L ++ +E+AK+ E + L + K+++ S+ Sbjct: 1000 --ERKLLEERISDLTTNL----AEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSR 1050
>MMRN2_HUMAN (Q9H8L6) Multimerin-2 precursor (EMILIN-3) (Elastin microfibril| interface located protein 3) (Elastin microfibril interfacer 3) (EndoGlyx-1 p125/p140 subunit) Length = 949 Score = 40.8 bits (94), Expect = 0.003 Identities = 38/159 (23%), Positives = 75/159 (47%), Gaps = 15/159 (9%) Frame = +2 Query: 50 EKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKHAAELEV 229 E D L+ +L ++++ L + T A +EE+ A T D+++ + E Sbjct: 365 EPDSLQARLGQLQRNLSELHMTTARREEELQYTLEDMRATLTRHVDEIKELYSESDETFD 424 Query: 230 QVSALDQQLQEAEIHY------------KNKVAEES-EKLALVNTQLNKLTQNVSKS-AE 367 Q+S +++Q++E ++++ K+ + EE+ E++ +LN Q++ A+ Sbjct: 425 QISKVERQVEELQVNHTALRELRVILMEKSLIMEENKEEVERQLLELNLTLQHLQGGHAD 484 Query: 368 MEKKVQDLE-QKLQLAYSKSDEQAKDAVVSTRSREFSLD 481 + K V+D QKL L E +DA + + SLD Sbjct: 485 LIKYVKDCNCQKLYLDLDVIREGQRDATRALEETQVSLD 523
>AKAP9_HUMAN (Q99996) A-kinase anchor protein 9 (Protein kinase A-anchoring| protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Hyperion protein) (Yotiao protei Length = 3911 Score = 40.8 bits (94), Expect = 0.003 Identities = 41/174 (23%), Positives = 84/174 (48%) Frame = +2 Query: 41 LVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKHAAE 220 L + Q + Q+LE++ EL + +EQ S ++ K+ E+AQ E Sbjct: 3126 LEYNIQQKQSQMLEMQVELSSMKDRATELQEQLSSEKMVVAELKS------ELAQTKL-E 3178 Query: 221 LEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEMEKKVQDLEQK 400 LE + A + L+E E ++ +V ++++++ L+N + L KS E++ ++ + K Sbjct: 3179 LETTLKAQHKHLKELEA-FRLEVKDKTDEVHLLN---DTLASEQKKSRELQWALEKEKAK 3234 Query: 401 LQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQAPSTASVNPAQQQL 562 L + + E+ +D +FSL+S +N + +L +N +QQ++ Sbjct: 3235 LGRSEERDKEELEDL-------KFSLESQKQRNLQLNLLLEQQKQLLNESQQKI 3281 Score = 35.8 bits (81), Expect = 0.11 Identities = 41/198 (20%), Positives = 81/198 (40%), Gaps = 13/198 (6%) Frame = +2 Query: 11 LTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVRE---IKWDAYKTYS 181 L K + + L+ K+QL++ + E +E+E + E+ V K + K + Sbjct: 2130 LKEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVRELEQALLVSADTFQKVEDRKHFG 2189 Query: 182 A----------DQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQL 331 A QL+ + E +++ L++QL++ +NK E + + Q Sbjct: 2190 AVEAKPELSLEVQLQAERDAIDRKEKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQK 2249 Query: 332 NKLTQNVSKSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQD 511 + T + + + K +D +KL LA +SD +ST+ + +E++ Sbjct: 2250 KESTTRLQELEQENKLFKDDMEKLGLAIKESD------AMSTQDQHVLFGKFAQIIQEKE 2303 Query: 512 LSQAPSTASVNPAQQQLR 565 + V QQQL+ Sbjct: 2304 VEIDQLNEQVTKLQQQLK 2321 Score = 32.3 bits (72), Expect = 1.2 Identities = 46/204 (22%), Positives = 90/204 (44%), Gaps = 25/204 (12%) Frame = +2 Query: 26 QEHANLVHEKDQL--EQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEV 199 ++H V K +L E QL R ++ + I N EEQ + ++ ++ E Sbjct: 2185 RKHFGAVEAKPELSLEVQLQAERDAIDRKEKEITNLEEQL-------EQFREELENKNEE 2237 Query: 200 AQKHAAELEVQVSALDQQLQEAEIHYKNKV-AEESEKLAL-------VNTQ-----LNKL 340 Q+ +LE+Q +LQE E +NK+ ++ EKL L ++TQ K Sbjct: 2238 VQQLHMQLEIQKKESTTRLQELE--QENKLFKDDMEKLGLAIKESDAMSTQDQHVLFGKF 2295 Query: 341 TQNVSKSA----EMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSL------T 490 Q + + ++ ++V L+Q+L++ + K+ ++ R E ++ L Sbjct: 2296 AQIIQEKEVEIDQLNEQVTKLQQQLKITTDNKVIEEKNELI--RDLETQIECLMSDQECV 2353 Query: 491 PQNKEQDLSQAPSTASVNPAQQQL 562 +N+E+++ Q + QQ+L Sbjct: 2354 KRNREEEIEQLNEV--IEKLQQEL 2375 Score = 32.0 bits (71), Expect = 1.6 Identities = 44/187 (23%), Positives = 82/187 (43%), Gaps = 4/187 (2%) Frame = +2 Query: 20 KMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEV 199 K E +L + LE+QL ++RK L+ EQA RE + D ++ +LE Sbjct: 2056 KNTELMDLRQQNQALEKQLEKMRKFLD----------EQAIDREHERDVFQQ-EIQKLEQ 2104 Query: 200 AQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAE-MEK 376 K + +++++ H K K + SE L L QL + Q ++ E +E Sbjct: 2105 QLKVVPRFQPISEHQTREVEQLANHLKEKTDKCSE-LLLSKEQLQRDIQERNEEIEKLEF 2163 Query: 377 KVQDLEQKLQLA---YSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQAPSTASVNP 547 +V++LEQ L ++ + K +++ V + E SL+ ++ + ++ Sbjct: 2164 RVRELEQALLVSADTFQKVEDRKHFGAVEAKP-ELSLEVQLQAERDAIDRKEKEITNLEE 2222 Query: 548 AQQQLRE 568 +Q RE Sbjct: 2223 QLEQFRE 2229 Score = 29.6 bits (65), Expect = 7.9 Identities = 25/123 (20%), Positives = 63/123 (51%), Gaps = 2/123 (1%) Frame = +2 Query: 65 EQQLLEVRKELEAAYR-TIANQEEQASVR-EIKWDAYKTYSADQLEVAQKHAAELEVQVS 238 E++L +++++LE +R I ++ + + + D + + ++E Q L + + Sbjct: 646 EEELSKLKEDLEIEHRINIEKLKDNLGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQN 705 Query: 239 ALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEMEKKVQDLEQKLQLAYS 418 L ++ + + ++ V +SE++ L Q+N+L + + + EK+ LEQ++Q Sbjct: 706 QLILEISKLKDLQQSLVNSKSEEMTL---QINELQKEIEILRQEEKEKGTLEQEVQELQL 762 Query: 419 KSD 427 K++ Sbjct: 763 KTE 765
>MYH6_RAT (P02563) Myosin heavy chain, cardiac muscle alpha isoform| (MyHC-alpha) Length = 1938 Score = 40.8 bits (94), Expect = 0.003 Identities = 40/167 (23%), Positives = 78/167 (46%), Gaps = 3/167 (1%) Frame = +2 Query: 53 KDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKHAA---EL 223 K ++E++L E +E+E A R N + DA + L V +K E+ Sbjct: 1570 KAEIERKLAEKDEEMEQAKR---NHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEM 1626 Query: 224 EVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEMEKKVQDLEQKL 403 E+Q+S ++ EA+ H KN A L +TQL +L V + ++++ + +E++ Sbjct: 1627 EIQLSQANRIASEAQKHLKNAQAH------LKDTQL-QLDDAVRANDDLKENIAIVERRN 1679 Query: 404 QLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQAPSTASVN 544 L ++ +E + RSR+ + L ++ L + +T+ +N Sbjct: 1680 TLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLIN 1726 Score = 38.1 bits (87), Expect = 0.022 Identities = 39/181 (21%), Positives = 83/181 (45%), Gaps = 35/181 (19%) Frame = +2 Query: 29 EHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQAS---------VREIKWDA----- 166 ++ +L+++K +++ L +++ E+E A + N EE+A E+K + Sbjct: 1720 QNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAH 1779 Query: 167 ----------------YKTYSADQLEV--AQKHAAELEVQVSALDQQLQEAEIHYKNKVA 292 ++ A+Q+ + +K +LE +V L+ +L EAE + + A Sbjct: 1780 LERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENEL-EAE---QKRNA 1835 Query: 293 EESEKLALVNTQLNKLTQNVSKSAEMEKKVQDLEQKLQL---AYSKSDEQAKDAVVSTRS 463 E + + ++ +LT + + ++QDL KLQL AY + E+A++ + S Sbjct: 1836 ESVKGMRKSERRIKELTYQTEEDKKNLVRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLS 1895 Query: 464 R 466 + Sbjct: 1896 K 1896
>MFP1_TOBAC (Q9M7J4) MAR binding filament-like protein 1-1| Length = 722 Score = 40.8 bits (94), Expect = 0.003 Identities = 42/178 (23%), Positives = 82/178 (46%), Gaps = 8/178 (4%) Frame = +2 Query: 5 EALTSKMQE-HANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKW-DAYKTY 178 E++ +K++E A V + + + +LL R ++ A +E QA V ++ + T Sbjct: 147 ESMKNKLKEKEATFVSMEKKFQSELLNER-DIRNNQLKRAGEERQALVNQLNSAKSTVTN 205 Query: 179 SADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSK 358 +L+ ++ A EL VQ+ L L + + K E EKL L+ K+T ++ Sbjct: 206 LGQELQKEKRIAEELIVQIEGLQNNLMQMKEDKKKLQEELKEKLDLIQVLQEKITLLTTE 265 Query: 359 SAEMEKKVQDLEQKLQLAYSKSD------EQAKDAVVSTRSREFSLDSLTPQNKEQDL 514 + E +Q KL S+ D ++++D +++ S E + Q +E++L Sbjct: 266 IKDKEASLQSTTSKLAEKESEVDKLSSMYQESQDQLMNLTS-EIKELKVEVQKREREL 322
>HOOK1_HUMAN (Q9UJC3) Hook homolog 1 (h-hook1) (hHK1)| Length = 728 Score = 40.8 bits (94), Expect = 0.003 Identities = 41/173 (23%), Positives = 87/173 (50%), Gaps = 8/173 (4%) Frame = +2 Query: 26 QEHANLVHEKDQLEQQ---LLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLE 196 ++H L+ EK++L +Q L E +EL + Q +Q + + A K+Y E Sbjct: 404 EKHEALLKEKERLIEQRDTLKETNEELRCS------QVQQDHLNQTDASATKSYENLAAE 457 Query: 197 VAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEE-SEKLALVNTQLNKLT--QNVSKSA- 364 + E+ +++ ++ L+ + +N+ EE E+L + ++N+L Q +SK Sbjct: 458 IMPVEYREVFIRLQHENKMLRLQQEGSENERIEELQEQLEQKHRKMNELETEQRLSKERI 517 Query: 365 -EMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQ 520 E++++++DL++ LQ SKS+ ++ + + E ++ LT ++E Q Sbjct: 518 RELQQQIEDLQKSLQEQGSKSEGESSSKL--KQKLEAHMEKLTEVHEELQKKQ 568 Score = 32.3 bits (72), Expect = 1.2 Identities = 32/135 (23%), Positives = 60/135 (44%), Gaps = 19/135 (14%) Frame = +2 Query: 59 QLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKHAAELEVQVS 238 Q E ++L +++E R I +EQ + K + +T + ++++ EL+ Q+ Sbjct: 471 QHENKMLRLQQEGSENER-IEELQEQLEQKHRKMNELET----EQRLSKERIRELQQQIE 525 Query: 239 ALDQQLQE--------AEIHYKNKVAEESEKLALVNTQLNK-----------LTQNVSKS 361 L + LQE + K K+ EKL V+ +L K + QNV K Sbjct: 526 DLQKSLQEQGSKSEGESSSKLKQKLEAHMEKLTEVHEELQKKQELIEDLQPDINQNVQKI 585 Query: 362 AEMEKKVQDLEQKLQ 406 E+E +Q ++ ++ Sbjct: 586 NELEAALQKKDEDMK 600
>CLPB_LISMO (Q8Y570) Chaperone clpB| Length = 866 Score = 40.4 bits (93), Expect = 0.004 Identities = 35/123 (28%), Positives = 66/123 (53%), Gaps = 3/123 (2%) Frame = +2 Query: 29 EHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQK 208 E A L EKD ++ LE+ + R +A+ +E+A+ + KW++ K E+++ Sbjct: 427 EEAALKEEKDPASERRLEILQ------RELADYKEEANQMKSKWESEKN------EISK- 473 Query: 209 HAAELEVQVSALDQQLQEAEIHYK-NKVAE-ESEKLALVNTQLNKL-TQNVSKSAEMEKK 379 E+ Q+ L +L+EAE +Y NK AE ++ V +L +L +N K+A+ ++ Sbjct: 474 -IREVREQIDHLRHELEEAENNYDLNKAAELRHGRIPAVEKELLELEAENREKTAQEDRI 532 Query: 380 VQD 388 +Q+ Sbjct: 533 LQE 535
>TPM2_BIOGL (P43689) Tropomyosin 2 (TMII)| Length = 284 Score = 40.4 bits (93), Expect = 0.004 Identities = 38/162 (23%), Positives = 76/162 (46%), Gaps = 17/162 (10%) Frame = +2 Query: 5 EALTSKM----QEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYK 172 +A+ KM E N + +Q+EQ++ +V + N +++ S + +D Sbjct: 2 DAIKKKMLAMKMEKENAIDRAEQMEQKVRDVEETKNKLEEEFNNLQKKFSNLQNDFDTAN 61 Query: 173 ---TYSADQLEVAQKHAAELEVQVSALDQQLQ---------EAEIHYKNKVAEESEKLAL 316 T + +LE ++KH AELE + L++++Q E + + EE+ K A Sbjct: 62 EGLTEAQTKLEASEKHVAELESDTAGLNRRIQLLEEDLERSEERLQSATEKLEEASKAAD 121 Query: 317 VNTQLNKLTQNVSKSAEMEKKVQDLEQKLQLA-YSKSDEQAK 439 + + K+ + S+S ++++ LE +L+ A Y D + K Sbjct: 122 ESERGRKVLE--SRSLADDERLDGLEAQLKEAKYIAEDAERK 161
>MYH1_HUMAN (P12882) Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1)| (Myosin heavy chain IIx/d) (MyHC-IIx/d) Length = 1939 Score = 40.4 bits (93), Expect = 0.004 Identities = 47/207 (22%), Positives = 87/207 (42%), Gaps = 19/207 (9%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKW-------- 160 E + ++ A ++ L ++L E+ + LE A + Q E RE ++ Sbjct: 1124 EEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLE 1183 Query: 161 DAYKTYSADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKL 340 +A + A + +KHA V+ L +Q+ + K K+ +E ++ + L Sbjct: 1184 EATLQHEATAATLRKKHADS----VAELGEQIDNLQ-RVKQKLEKEKSEMKMEIDDLASN 1238 Query: 341 TQNVSKS-AEMEKKVQDLEQKLQLAYSKSDEQ--------AKDAVVSTRSREFS--LDSL 487 + VSK+ +EK + LE +L +K +EQ A+ A + T S E+S LD Sbjct: 1239 METVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEK 1298 Query: 488 TPQNKEQDLSQAPSTASVNPAQQQLRE 568 + + T + ++QL E Sbjct: 1299 DTLVSQLSRGKQAFTQQIEELKRQLEE 1325 Score = 33.1 bits (74), Expect = 0.72 Identities = 39/171 (22%), Positives = 72/171 (42%), Gaps = 32/171 (18%) Frame = +2 Query: 29 EHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQK 208 ++ +L++ K +LE + +++ E+E + N EE+A ++ DA A++L+ Q Sbjct: 1723 QNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKA--KKAITDA--AMMAEELKKEQD 1778 Query: 209 HAAELEVQVSALDQ----------------------QLQEAEIHYKNKVAE-ESEKLALV 319 +A LE L+Q Q+Q+ E + E ESE+ V Sbjct: 1779 TSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNV 1838 Query: 320 NT---------QLNKLTQNVSKSAEMEKKVQDLEQKLQLAYSKSDEQAKDA 445 ++ +LT + + ++QDL KLQ QA++A Sbjct: 1839 EAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEA 1889
>TAXB1_RAT (Q66HA4) Tax1-binding protein 1 homolog (Liver regeneration-related| protein LRRG004) Length = 813 Score = 40.4 bits (93), Expect = 0.004 Identities = 40/145 (27%), Positives = 66/145 (45%) Frame = +2 Query: 26 QEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQ 205 +E ++ V+ +D+ L R E E + +A+ + + +K D KT D LE Sbjct: 375 KELSDAVNVRDKTMADLHTARLENERVKKQLADTLAELQLHAVKTDQEKT---DTLE--- 428 Query: 206 KHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEMEKKVQ 385 EL +V L +LQ A HYK K +E ++L Q+NKL+ + S + K Sbjct: 429 ---HELRREVEDLKLRLQMAADHYKEKF-KECQRL---QKQINKLSDQSASSNGVFTKRM 481 Query: 386 DLEQKLQLAYSKSDEQAKDAVVSTR 460 +QK+ A +D A + V + Sbjct: 482 GSQQKVNDASINTDPAASASAVDVK 506
>MYH3_CHICK (P02565) Myosin heavy chain, fast skeletal muscle, embryonic| Length = 1940 Score = 40.4 bits (93), Expect = 0.004 Identities = 43/196 (21%), Positives = 88/196 (44%), Gaps = 10/196 (5%) Frame = +2 Query: 11 LTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQ 190 L ++Q A+ + + ++ QL++ + +LEA + + + E + A K D+ Sbjct: 892 LQLQVQAEADGLADAEERCDQLIKTKIQLEAKIKELTERAEDEEEMNAELTAKKRKLEDE 951 Query: 191 LEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEM 370 +K +LE+ ++ ++++ E NKV +E++A ++ + KLT+ E Sbjct: 952 CSELKKDIDDLELTLAKVEKEKHATE----NKVKNLTEEMAALDETIAKLTKEKKALQEA 1007 Query: 371 EKKV-------QDLEQKLQLAYSKSDEQAKDAVVS-TRSREFSLDSLTPQNK-EQDLSQA 523 ++ +D L A +K ++Q D S + ++ +D + K E DL Sbjct: 1008 HQQTLDDLQAEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKMT 1067 Query: 524 -PSTASVNPAQQQLRE 568 ST + +QQL E Sbjct: 1068 QESTMDLENDKQQLDE 1083 Score = 38.9 bits (89), Expect = 0.013 Identities = 51/213 (23%), Positives = 91/213 (42%), Gaps = 38/213 (17%) Frame = +2 Query: 29 EHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQK 208 ++ +L++ K +LE + +++ E+E + N EE+A ++ DA A++L+ Q Sbjct: 1724 QNTSLINTKKKLESDISQIQSEMEDTIQEARNAEEKA--KKAITDA--AMMAEELKKEQD 1779 Query: 209 HAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVN--TQLNKLTQNV---------- 352 +A LE LDQ +++ + +E+E+LAL Q+ KL V Sbjct: 1780 TSAHLERMKKNLDQTVKDLQHRL-----DEAEQLALKGGKKQIQKLEARVRELEGEVDAE 1834 Query: 353 -SKSAEMEK------------------------KVQDLEQKLQLAYSKSDEQAKDAVVST 457 +SAE K ++QDL KLQ+ QA++A Sbjct: 1835 QKRSAEAVKGVRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQMKVKSYKRQAEEA---- 1890 Query: 458 RSREFSLDSLTPQNK-EQDLSQAPSTASVNPAQ 553 E S +L+ K + +L +A A + +Q Sbjct: 1891 --EELSNVNLSKFRKIQHELEEAEERADIAESQ 1921 Score = 38.5 bits (88), Expect = 0.017 Identities = 43/177 (24%), Positives = 77/177 (43%), Gaps = 20/177 (11%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKW-------- 160 E + ++ A + L ++L E+ + LE A A Q + RE ++ Sbjct: 1125 EEIEAERTSRAKAEKHRADLSRELEEISERLEEAGGATAAQIDMNKKREAEFQKMRRDLE 1184 Query: 161 DAYKTYSADQLEVAQKHA---AELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQL 331 +A + A + +KHA A++ Q+ L + K K+ +E +L + L Sbjct: 1185 EATLQHEATAAALRKKHADSTADVGEQIDNLQR--------VKQKLEKEKSELKMEIDDL 1236 Query: 332 NKLTQNVSKS-AEMEKKVQDLEQKLQLAYSKSDEQ--------AKDAVVSTRSREFS 475 ++VSK+ A +EK + LE +L +K +EQ A+ A + T S E+S Sbjct: 1237 ASNMESVSKAKANLEKMCRSLEDQLSEIKTKEEEQQRTINDISAQKARLQTESGEYS 1293 Score = 29.6 bits (65), Expect = 7.9 Identities = 30/151 (19%), Positives = 70/151 (46%), Gaps = 10/151 (6%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQQLLEVRKELE---AAYRTIANQEEQASVREIKWDAYKT 175 EA+ SK A+L K +L+ ++ ++ ++E AA + +++ +W Sbjct: 1410 EAVNSKC---ASLEKTKQRLQNEVEDLMIDVERSNAACAALDKKQKNFDKILSEWKQKYE 1466 Query: 176 YSADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVS 355 + +LE +QK + L ++ + +E+ H + E + +++ LT+ ++ Sbjct: 1467 ETQAELEASQKESRSLSTELFKMKNAYEESLDHLETLKRENKN----LQQEISDLTEQIA 1522 Query: 356 KSA----EMEKKVQDLEQ---KLQLAYSKSD 427 + E+EK + +EQ +LQ A +++ Sbjct: 1523 EGGKAIHELEKVKKQIEQEKSELQTALEEAE 1553
>RRBP1_CANFA (Q28298) Ribosome-binding protein 1 (180 kDa ribosome receptor) (RRp)| Length = 1534 Score = 40.4 bits (93), Expect = 0.004 Identities = 39/154 (25%), Positives = 64/154 (41%) Frame = +2 Query: 14 TSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQL 193 TS+++ N E +L Q+L +V KEL +E+Q E K Sbjct: 945 TSQVESKQNT--ELAKLRQELSKVSKELVEKSEAARQEEQQRKALETK------------ 990 Query: 194 EVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEME 373 A LE QV L +E+E + ++ E S +L T L + K+ E + Sbjct: 991 ------TAALEKQVLQLQASHKESEEALQKRLDEVSRELCRSQTSHASLRADAEKAQEQQ 1044 Query: 374 KKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFS 475 +++ +L KL Q+ +A V ++S E S Sbjct: 1045 QQMAELHSKL---------QSSEAEVKSKSEELS 1069 Score = 37.4 bits (85), Expect = 0.038 Identities = 43/198 (21%), Positives = 87/198 (43%), Gaps = 10/198 (5%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQL---EQQLLEVRKELEAAYRTIAN--QEEQASVREIKWDAY 169 E K + A K QL EQ++ V+ +EA+YR Q+ Q +R ++ Sbjct: 861 ELAAEKAKAAAGEAKVKKQLVAREQEITAVQARIEASYREHVKEVQQLQGKIRTLQ---- 916 Query: 170 KTYSADQLEVA-QKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQ 346 +QLE A L+ + S L L +A ++K ++ +LA + +L+K+++ Sbjct: 917 -----EQLENGPNTQLARLQQENSILRDALNQATSQVESK---QNTELAKLRQELSKVSK 968 Query: 347 NVSKSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFS----LDSLTPQNKEQDL 514 + + +E ++ + + L+ + ++Q S + E + LD ++ + Sbjct: 969 ELVEKSEAARQEEQQRKALETKTAALEKQVLQLQASHKESEEALQKRLDEVSRELCRSQT 1028 Query: 515 SQAPSTASVNPAQQQLRE 568 S A A AQ+Q ++ Sbjct: 1029 SHASLRADAEKAQEQQQQ 1046 Score = 32.3 bits (72), Expect = 1.2 Identities = 31/126 (24%), Positives = 59/126 (46%), Gaps = 2/126 (1%) Frame = +2 Query: 65 EQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKHAAELEVQVSA- 241 EQ +E++ +LE T+ ++EQA R++ + + S+ A + AELE S Sbjct: 1409 EQDPVELKAQLERTEATL--EDEQALRRKLTAEFQEAQSS-----ACRLQAELEKLRSTG 1461 Query: 242 -LDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEMEKKVQDLEQKLQLAYS 418 L+ E K ++ +E + + + KL + + + E K +D +KLQ Sbjct: 1462 PLESSAAEEATQLKERLEKEKKLTSDLGHAATKLQELLKTTQEQLAKERDTVKKLQEQLD 1521 Query: 419 KSDEQA 436 K+D+ + Sbjct: 1522 KTDDSS 1527
>KTN1_CHICK (Q90631) Kinectin| Length = 1364 Score = 40.4 bits (93), Expect = 0.004 Identities = 45/184 (24%), Positives = 77/184 (41%), Gaps = 3/184 (1%) Frame = +2 Query: 17 SKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSAD-QL 193 S + E ++HEKD ++ V + L+A +AN+E+ K +A K + QL Sbjct: 797 SLVDELQKVIHEKDG---KIKSVEELLQAEILKVANKEKTVQALTQKIEALKEEVGNSQL 853 Query: 194 EVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEME 373 E+ ++ + QV L L+ E K A EK + + +L A++ Sbjct: 854 EMEKQ--VSITSQVKELQTLLKGKENQVKTMEALLEEKEKEIVQKGERLKGQQDTVAQLT 911 Query: 374 KKVQDLEQK--LQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQAPSTASVNP 547 KVQ+LEQ+ QL + Q +D R E + L +E++ A + Sbjct: 912 SKVQELEQQNLQQLQQVPAASQVQDLESRLRGEEEQISKLKAVLEEKEREIASQVKQLQT 971 Query: 548 AQQQ 559 Q + Sbjct: 972 MQSE 975 Score = 29.6 bits (65), Expect = 7.9 Identities = 30/140 (21%), Positives = 61/140 (43%), Gaps = 1/140 (0%) Frame = +2 Query: 11 LTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQ 190 L Q+ A LV+E + +L + + + A + +A + Q E +W+ Sbjct: 442 LNKLRQDCARLVNELGEKNSKLQQEELQKKNAEQAVAQLKVQQQEAERRWE--------- 492 Query: 191 LEVAQKHAAELEVQVSALDQQLQEAEIHYKNK-VAEESEKLALVNTQLNKLTQNVSKSAE 367 E++V + + + A+ +NK VA+++E + + +KLT V + Sbjct: 493 ---------EIQVYLRKRTAEHEAAQQDVQNKLVAKDNE----IQSLHSKLTDMVVSKQQ 539 Query: 368 MEKKVQDLEQKLQLAYSKSD 427 +E+++ L + Q SK D Sbjct: 540 LEQRMLQLIESEQKRASKED 559
>NUF1_YEAST (P32380) Protein NUF1 (Spindle poly body spacer protein SPC110)| Length = 944 Score = 40.4 bits (93), Expect = 0.004 Identities = 46/203 (22%), Positives = 92/203 (45%), Gaps = 15/203 (7%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSA 184 E SK + +L + QLE L ++K + +TI + E ++ + IK Sbjct: 427 EETVSKDERIIDLQKKVKQLENDLFVIKKT-HSESKTITDNELESKDKLIK------ILE 479 Query: 185 DQLEVAQKHAAELEVQVSALDQQLQEAEIHY----------KNKVAEESEKLALVNTQL- 331 + L+VAQ+ +++E ++L+E E +Y K + E+ LA N+QL Sbjct: 480 NDLKVAQEKYSKME-------KELKEREFNYKISESKLEDEKTTLNEKISNLAAENSQLK 532 Query: 332 NKLTQNVSKSAEM----EKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQN 499 NK+ N + + M EK+++ L + ++ Y +S + ++D + + R + + Sbjct: 533 NKIEDNSTATHHMKENYEKQLESLRKDIE-EYKESAKDSEDKIEELKIRIAENSAKVSEK 591 Query: 500 KEQDLSQAPSTASVNPAQQQLRE 568 + +D+ Q S +L+E Sbjct: 592 RSKDIKQKDEQISDLTQNLKLQE 614 Score = 39.3 bits (90), Expect = 0.010 Identities = 47/199 (23%), Positives = 85/199 (42%), Gaps = 23/199 (11%) Frame = +2 Query: 11 LTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQ 190 L SK E NL++E ++L+ E +LE + + + + +IK D Q Sbjct: 264 LRSKEDELKNLMNELNELKSNAEEKDTQLEFKKNELRKRTNELNELKIKSDEMDL----Q 319 Query: 191 LEVAQKHAAELEVQVSALDQQLQEAEIH----------YKNKVAEESEKLALVNTQL--- 331 L+ Q + L+ +++ L+ + E KNK+AE E+++ N+QL Sbjct: 320 LKQKQNESKRLKDELNELETKFSENGSQSSAKENELKMLKNKIAELEEEISTKNSQLIAK 379 Query: 332 --------NKLTQNVSKSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSL 487 +LTQ SK + + ++ E++L+ K + + A T S++ + L Sbjct: 380 EGKLASLMAQLTQLESKLNQRDSQLGSREEELKKTNDKLQKDIRIAREETVSKDERIIDL 439 Query: 488 TPQNK--EQDLSQAPSTAS 538 + K E DL T S Sbjct: 440 QKKVKQLENDLFVIKKTHS 458
>REST_HUMAN (P30622) Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170)| (Reed-Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1) Length = 1427 Score = 40.0 bits (92), Expect = 0.006 Identities = 30/144 (20%), Positives = 69/144 (47%), Gaps = 2/144 (1%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSA 184 E L + + EKD+ E+QL++ +++LE I S + K + Sbjct: 885 EKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMN------- 937 Query: 185 DQLEVAQKHAAELEVQVSALDQQLQ--EAEIHYKNKVAEESEKLALVNTQLNKLTQNVSK 358 D+L + ++ EL+++++ ++ + I AE+S++ A ++ + Sbjct: 938 DELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEA--------AKKHEEE 989 Query: 359 SAEMEKKVQDLEQKLQLAYSKSDE 430 E+E+K+ DLE+K++ ++++ E Sbjct: 990 KKELERKLSDLEKKMETSHNQCQE 1013 Score = 30.8 bits (68), Expect = 3.6 Identities = 36/165 (21%), Positives = 68/165 (41%), Gaps = 6/165 (3%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSA 184 EAL K Q L+ E+D ++ + + + +A + ++ +A Sbjct: 355 EALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALARDGHDQHVLELEAKMDQLR 414 Query: 185 DQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSA 364 +E A + EL Q+ +++++ + +V EES + TQ KL Sbjct: 415 TMVEAADREKVELLNQLEEEKRKVEDLQF----RVEEESITKGDLETQ-TKLE------- 462 Query: 365 EMEKKVQDLEQKLQLAYSKSD------EQAKDAVVSTRSREFSLD 481 ++++LEQ L +K+D E + A VS +SR L+ Sbjct: 463 --HARIKELEQSLLFEKTKADKLQRELEDTRVATVSEKSRIMELE 505
>PLEC1_CRIGR (Q9JI55) Plectin-1 (PLTN) (PCN) (300-kDa intermediate| filament-associated protein) (IFAP300) (Fragment) Length = 4473 Score = 40.0 bits (92), Expect = 0.006 Identities = 29/132 (21%), Positives = 63/132 (47%), Gaps = 20/132 (15%) Frame = +2 Query: 53 KDQLEQQLLEVRKELEAAYRTIANQEEQASVR------------EIKWDAYKTYSADQLE 196 ++Q E++ + RK++E A R + EEQA R E + +A + A+Q Sbjct: 2023 REQAEREAAQSRKQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAA 2082 Query: 197 VAQKHAAELEV--------QVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNV 352 + QK AA+ E+ Q Q+++ + ++ E + ++++ +L +L V Sbjct: 2083 LKQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKSILDEELQRLKAEV 2142 Query: 353 SKSAEMEKKVQD 388 +++A +V++ Sbjct: 2143 TEAARQRSQVEE 2154 Score = 40.0 bits (92), Expect = 0.006 Identities = 39/151 (25%), Positives = 65/151 (43%), Gaps = 7/151 (4%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSA 184 E L +E H++ +LE +L +VR E+E + A EE++ K A Sbjct: 1660 EELARLQREATAATHKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEA 1719 Query: 185 DQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEE----SEKLALVN--TQLNKLTQ 346 D+ + AA L +Q Q AE + AE +EKLA ++ T+L + Sbjct: 1720 DRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLTEKLAAISEATRLKTEAE 1779 Query: 347 NVSKSAEME-KKVQDLEQKLQLAYSKSDEQA 436 K E E ++++ L + + +EQA Sbjct: 1780 IALKEKEAENERLRRLAEDEAFQRRRLEEQA 1810 Score = 37.7 bits (86), Expect = 0.029 Identities = 36/151 (23%), Positives = 68/151 (45%), Gaps = 4/151 (2%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSA 184 E + + + N +K ++++L +R+ EA + A Q E A ++ + Sbjct: 1325 EEVARREEAAVNAQQQKRSIQEELQHLRQSSEAEIQAKAQQVEAAERSRMRIEEEIRVVR 1384 Query: 185 DQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKL-ALVNTQLNKLTQNVSKS 361 QLE ++ E ++ AL + +EAE K + EE+E+L V + + Q ++ Sbjct: 1385 LQLETTERQRGGAEGELQALRARAEEAEAQ-KRQAQEEAERLRRQVQDESQRKRQAEAEL 1443 Query: 362 AEMEKKVQDLEQKLQLAYSKSDE---QAKDA 445 A K + Q+ Q A +E QA++A Sbjct: 1444 ALRVKAQAEAAQEKQRALQALEELRLQAEEA 1474 Score = 35.4 bits (80), Expect = 0.14 Identities = 48/187 (25%), Positives = 79/187 (42%), Gaps = 10/187 (5%) Frame = +2 Query: 47 HEKDQLEQQLLEVRKEL-EAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKHAAEL 223 H+K L+++L ++ E+ EAA + +EE SVR Q+E K A + Sbjct: 2126 HQKSILDEELQRLKAEVTEAARQRSQVEEELFSVRV------------QMEELGKLKARI 2173 Query: 224 EVQVSAL-------DQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEMEKKV 382 E + AL Q+ E E +VAEE+ +L++ + +L Q Sbjct: 2174 EAENRALILRDKDNTQRFLEEEAEKMKQVAEEAARLSVAAQEAARLRQLAE--------- 2224 Query: 383 QDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKE--QDLSQAPSTASVNPAQQ 556 +DL Q+ LA E+ + +TR + + L Q KE Q+ ++ AQQ Sbjct: 2225 EDLAQQRALAEKMLKEKMQAVQEATRLKAEA--ELLQQQKELAQEQARRLQEDKEQMAQQ 2282 Query: 557 QLREPSG 577 + E G Sbjct: 2283 LVEETQG 2289 Score = 34.7 bits (78), Expect = 0.25 Identities = 36/144 (25%), Positives = 66/144 (45%), Gaps = 2/144 (1%) Frame = +2 Query: 44 VHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKHAAEL 223 + K+Q EQ+ A R +A +EEQ RE + K+ +A++ Q+ AA Sbjct: 1885 MRSKEQAEQEA--------ARQRQLAAEEEQRR-REAEERVQKSLAAEEEAARQRKAALE 1935 Query: 224 EVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAE--MEKKVQDLEQ 397 EV+ L +++EA + E + +L L K Q K+ ++++ ++L+Q Sbjct: 1936 EVE--RLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFVVQQREEELQQ 1993 Query: 398 KLQLAYSKSDEQAKDAVVSTRSRE 469 LQ S + +A + R+ E Sbjct: 1994 TLQQEQSMLERLRGEAEAARRAAE 2017
>DESP_HUMAN (P15924) Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus| antigen) Length = 2871 Score = 40.0 bits (92), Expect = 0.006 Identities = 34/180 (18%), Positives = 72/180 (40%), Gaps = 3/180 (1%) Frame = +2 Query: 38 NLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKHAA 217 NL E L +++ ++ L + EE ++ A EV+Q+ Sbjct: 1397 NLTRENRSLSEEIKRLKNTLTQTTENLRRVEEDIQQQK----------ATGSEVSQRKQ- 1445 Query: 218 ELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEMEKKVQDLE- 394 +LEV++ + Q E + YK + + ++ + N ++ +L Q + K K ++D Sbjct: 1446 QLEVELRQVTQMRTEESVRYKQSLDDAAKTIQDKNKEIERLKQLIDKETNDRKCLEDENA 1505 Query: 395 --QKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQAPSTASVNPAQQQLRE 568 Q++Q K++ A + + + +E L L + + + Q L+E Sbjct: 1506 RLQRVQYDLQKANSSATETINKLKVQEQELTRLRIDYERVSQERTVKDQDITRFQNSLKE 1565
>RAD50_HUMAN (Q92878) DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50)| Length = 1312 Score = 40.0 bits (92), Expect = 0.006 Identities = 33/129 (25%), Positives = 61/129 (47%), Gaps = 12/129 (9%) Frame = +2 Query: 92 ELEAAYRTIANQEEQASVREIKWDAYKTYSAD--QLEVAQKHAAELEVQVSALDQQLQ-- 259 E+ +A R I E VR+ + K Y + L+ ++ A E+ Q+++ + QL Sbjct: 178 EIFSATRYIKALETLRQVRQTQGQKVKEYQMELKYLKQYKEKACEIRDQITSKEAQLTSS 237 Query: 260 -------EAEIH-YKNKVAEESEKLALVNTQLNKLTQNVSKSAEMEKKVQDLEQKLQLAY 415 E E+ KN++ E L+ + N++ S+ +MEK +LE+K++ + Sbjct: 238 KEIVKSYENELDPLKNRLKEIEHNLSKIMKLDNEIKALDSRKKQMEKDNSELEEKMEKVF 297 Query: 416 SKSDEQAKD 442 +DEQ D Sbjct: 298 QGTDEQLND 306
>CNN_DROME (P54623) Centrosomin (Protein arrow)| Length = 1320 Score = 40.0 bits (92), Expect = 0.006 Identities = 44/171 (25%), Positives = 78/171 (45%), Gaps = 6/171 (3%) Frame = +2 Query: 26 QEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQ 205 QE + QLEQ L + + L A I + EE+ V + K DQL++A Sbjct: 926 QEQLRCLDITQQLEQ-LRAINEALTADLHAIGSHEEERMVELQRQLELKNQQIDQLKLAH 984 Query: 206 K----HAAELEVQVSALDQQLQEAE-IHYKNKVAEESEKLALVNTQLNKLTQN-VSKSAE 367 + E+++ AL QQ+QE E +H ++ + + +QL KL + V + E Sbjct: 985 STLTADSQITEMELQALQQQMQEIEQLH--------ADSVETLQSQLQKLKLDAVQQLEE 1036 Query: 368 MEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQ 520 E+ ++ ++ +A + EQA+ + RS ++ Q E++L Q Sbjct: 1037 HERLHREALERDWVALTTYQEQAQQLLELQRSLDYH------QENEKELKQ 1081
>CEP2_HUMAN (Q9BV73) Centrosomal protein 2 (Centrosomal Nek2-associated protein| 1) (C-NAP1) (Centrosome protein 250) (Centrosome-associated protein CEP250) Length = 2442 Score = 40.0 bits (92), Expect = 0.006 Identities = 41/173 (23%), Positives = 85/173 (49%), Gaps = 12/173 (6%) Frame = +2 Query: 26 QEHANLVHE-KDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYS------- 181 QEH + + E KDQLEQQL + +++ ++ +E++ V + + + Sbjct: 1742 QEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSL 1801 Query: 182 ADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLN-KLTQNVSK 358 QL+ AQ+ A+ + ++ AL Q+ Q+A+ + +V E+++ L Q + L + + Sbjct: 1802 QSQLDEAQRALAQRDQELEALQQEQQQAQ-GQEERVKEKADALQGALEQAHMTLKERHGE 1860 Query: 359 SAEMEKKVQDLEQKLQL---AYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQ 508 + +++ + LE++L + +E D +R +E +L +L Q EQ Sbjct: 1861 LQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQEKALLALQQQCAEQ 1913 Score = 40.0 bits (92), Expect = 0.006 Identities = 48/202 (23%), Positives = 95/202 (47%), Gaps = 19/202 (9%) Frame = +2 Query: 11 LTSKMQEHANLVHEKDQLEQQLLEVRKELEAA--YRTIANQEEQASVRE------IKWDA 166 L + +E ++L+ +K L++Q+ +++ +L A + + QE Q +RE I+ + Sbjct: 991 LAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKEL 1050 Query: 167 YKTYSADQLEVAQKHAAELEVQ---------VSALDQQLQEAEIHYKNKVAE-ESEKLAL 316 + ++ L + +K L +Q +SAL Q +QEA+ K A+ E + + Sbjct: 1051 EREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQMELLRQEV 1110 Query: 317 VNTQLNKLTQNVSKSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQ 496 + + L Q E+E EQ+L+ + + +A + RS E L++L + Sbjct: 1111 KEKEADFLAQEAQLLEELEAS-HITEQQLRASLWAQEAKAAQLQLRLRSTESQLEALAAE 1169 Query: 497 NKEQDLSQAPS-TASVNPAQQQ 559 + + +QA + AS+ A QQ Sbjct: 1170 QQPGNQAQAQAQLASLYSALQQ 1191 Score = 38.1 bits (87), Expect = 0.022 Identities = 42/184 (22%), Positives = 83/184 (45%), Gaps = 11/184 (5%) Frame = +2 Query: 41 LVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASV-----------REIKWDAYKTYSAD 187 L +K L QQLL++ +E ++ + E+ + RE W+ T+ Sbjct: 608 LALDKVGLNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEAEKRREALWEK-NTHLEA 666 Query: 188 QLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAE 367 QL+ A++ AEL+ + + +QE + + K++E + TQL +L Q + E Sbjct: 667 QLQKAEEAGAELQADL----RDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEE 722 Query: 368 MEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQAPSTASVNP 547 + + +++K L K+ + + V R R+ + L + ++L + +S+ Sbjct: 723 VLARA--VQEKEALVREKAALEVRLQAVE-RDRQDLAEQLQGLSSAKELLE----SSLFE 775 Query: 548 AQQQ 559 AQQQ Sbjct: 776 AQQQ 779 Score = 37.4 bits (85), Expect = 0.038 Identities = 46/203 (22%), Positives = 82/203 (40%), Gaps = 28/203 (13%) Frame = +2 Query: 38 NLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKHAA 217 +L EK +LE +L E + E+EA QA E + A QLE ++ + Sbjct: 879 SLEREKMELEMRLKEQQTEMEAI---------QAQREEERTQAESALCQMQLETEKERVS 929 Query: 218 ELEV------QVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSA----- 364 LE +++ QQL+ K + +E E ++ TQL + + + ++A Sbjct: 930 LLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQHRD 989 Query: 365 -----------------EMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTP 493 +++K+V+DL K QL ++ + V + RE Sbjct: 990 DLAALQEESSSLLQDKMDLQKQVEDL--KSQLVAQDDSQRLVEQEVQEKLRE--TQEYNR 1045 Query: 494 QNKEQDLSQAPSTASVNPAQQQL 562 KE + +A T S+ +Q+L Sbjct: 1046 IQKELEREKASLTLSLMEKEQRL 1068 Score = 32.7 bits (73), Expect = 0.94 Identities = 37/150 (24%), Positives = 69/150 (46%), Gaps = 14/150 (9%) Frame = +2 Query: 38 NLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKHAA 217 ++ EK++++++L E R + EAA Q EQ + + + + E + A Sbjct: 684 DIQEEKEEIQKKLSESRHQQEAA----TTQLEQLHQEAKRQEEVLARAVQEKEALVREKA 739 Query: 218 ELEVQVSALDQQLQE-AEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEMEKKVQDLE 394 LEV++ A+++ Q+ AE A+E + +L Q V+K ++E ++Q + Sbjct: 740 ALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVIEVTK-GQLEVQIQTVT 798 Query: 395 Q------------KLQLAYSKSD-EQAKDA 445 Q KL+L +S EQ +DA Sbjct: 799 QAKEVIQGEVRCLKLELDTERSQAEQERDA 828 Score = 30.0 bits (66), Expect = 6.1 Identities = 26/86 (30%), Positives = 43/86 (50%), Gaps = 4/86 (4%) Frame = +2 Query: 188 QLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAE 367 ++E Q+H EL+ L+QQLQ KV E S L+ ++ L Q + ++ E Sbjct: 1737 EVECQQEHIHELQELKDQLEQQLQGLH----RKVGETSLLLSQREQEIVVLQQQLQEARE 1792 Query: 368 M-EKKVQDLEQKL---QLAYSKSDEQ 433 E K Q L+ +L Q A ++ D++ Sbjct: 1793 QGELKEQSLQSQLDEAQRALAQRDQE 1818
>TOLA_ECOLI (P19934) Protein tolA| Length = 421 Score = 40.0 bits (92), Expect = 0.006 Identities = 42/159 (26%), Positives = 69/159 (43%), Gaps = 4/159 (2%) Frame = +2 Query: 2 NEALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYS 181 +E K Q+ A + EK EQ+ L K+LE +A QE++ E + Sbjct: 78 DEQRKMKEQQAAEELREKQAAEQERL---KQLEK--ERLAAQEQKKQAEE---------A 123 Query: 182 ADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKS 361 A Q E+ QK A E + +A + EA+ K AEE+ K A + + + + Sbjct: 124 AKQAELKQKQAEEAAAKAAADAKAKAEADA----KAAEEAAKKAAADAKKKAEAEAAKAA 179 Query: 362 AEMEKKVQ----DLEQKLQLAYSKSDEQAKDAVVSTRSR 466 AE +KK + L++K + A + + E K A + Sbjct: 180 AEAQKKAEAAAAALKKKAEAAEAAAAEARKKAATEAAEK 218
>PLEC1_HUMAN (Q15149) Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1)| Length = 4684 Score = 40.0 bits (92), Expect = 0.006 Identities = 37/140 (26%), Positives = 65/140 (46%), Gaps = 2/140 (1%) Frame = +2 Query: 92 ELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKHAAELEVQVSALDQQLQEAEI 271 ELEAA + EE+ RE + K+ +A++ Q+ AA EV+ L +++EA Sbjct: 2103 ELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVE--RLKAKVEEARS 2160 Query: 272 HYKNKVAEESEKLALVNTQLNKLTQNVSK--SAEMEKKVQDLEQKLQLAYSKSDEQAKDA 445 + E + +L L K Q K + +++K Q+L+Q LQ S D +A Sbjct: 2161 LRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDRLRGEA 2220 Query: 446 VVSTRSREFSLDSLTPQNKE 505 + R+ E + ++ +E Sbjct: 2221 EAARRAAEEAEEARVQAERE 2240 Score = 37.4 bits (85), Expect = 0.038 Identities = 44/211 (20%), Positives = 89/211 (42%), Gaps = 23/211 (10%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSA 184 E + + + + +K ++++L ++R+ EA + A Q E A ++ + Sbjct: 1536 EEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVR 1595 Query: 185 DQLEVAQKHAAELEVQVSALDQQLQEAEIH----------YKNKVAEESEKLALVNTQL- 331 QLE ++ E ++ AL + +EAE + +V +ES++ +L Sbjct: 1596 LQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELA 1655 Query: 332 NKLTQNVSKSAEMEKKVQDLEQKLQLAYSKSD--------EQAKDAVV----STRSREFS 475 +++ + E ++ +Q LE+ L+L +++ E+A+ V + RS E Sbjct: 1656 SRVKAEAEAAREKQRALQALEE-LRLQAEEAERWLCQAEVERARQVQVALETAQRSAEAE 1714 Query: 476 LDSLTPQNKEQDLSQAPSTASVNPAQQQLRE 568 L S E+ S + A QLRE Sbjct: 1715 LQSKRASFAEKTAQLERSLQEEHVAVAQLRE 1745 Score = 35.4 bits (80), Expect = 0.14 Identities = 38/151 (25%), Positives = 63/151 (41%), Gaps = 7/151 (4%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSA 184 E L +E A ++ +LE +L +VR E+E + A EE++ K A Sbjct: 1871 EELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKAKAEEESRSTSEKSKQRLEAEA 1930 Query: 185 DQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEE----SEKLALVN--TQLNKLTQ 346 + + AA L +Q Q AE + AE +EKLA + T+L + Sbjct: 1931 GRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAE 1990 Query: 347 NVSKSAEME-KKVQDLEQKLQLAYSKSDEQA 436 K E E ++++ L + + +EQA Sbjct: 1991 IALKEKEAENERLRRLAEDEAFQRRRLEEQA 2021 Score = 34.3 bits (77), Expect = 0.32 Identities = 39/170 (22%), Positives = 78/170 (45%), Gaps = 12/170 (7%) Frame = +2 Query: 47 HEKDQLEQQLLEVRKE-LEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKHAAEL 223 H+K+ L+++L ++ E EAA + +EE SVR Q+E K A + Sbjct: 2337 HQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRV------------QMEELSKLKARI 2384 Query: 224 EVQVSAL-------DQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEMEKKV 382 E + AL Q+ + E +VAEE+ +L++ + +L Q + ++ + Sbjct: 2385 EAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRAL 2444 Query: 383 QD--LEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSL--TPQNKEQDLSQ 520 + L++K+Q A ++ +A + + +E + + ++KEQ Q Sbjct: 2445 AEKMLKEKMQ-AVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQ 2493
>SDCG8_MOUSE (Q80UF4) Serologically defined colon cancer antigen 8 (Centrosomal| colon cancer autoantigen protein) (mCCCAP) Length = 717 Score = 39.7 bits (91), Expect = 0.008 Identities = 39/181 (21%), Positives = 72/181 (39%), Gaps = 24/181 (13%) Frame = +2 Query: 50 EKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKHAAELEV 229 EK+ +++++ R++ E+ ++ + + K KT + LE Q H A E+ Sbjct: 393 EKEMIKKEVAREREDAESKMLILSQNIAKLEAQVEKVTREKTAAVSHLEEIQNHVASQEM 452 Query: 230 QVSA----LDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSK-SAEMEKKVQDLE 394 V+ + QL + ++ E E A + L Q + K E+ + Q +E Sbjct: 453 DVTKVCGEMRFQLNKTKMEKDEVEKEHREYKAKSHKDLEMKVQEIEKLRLELSESEQHVE 512 Query: 395 QKLQLAYSKSDE-------------------QAKDAVVSTRSREFSLDSLTPQNKEQDLS 517 Q+ Q A E KD++ + S E +L Q +EQ+L+ Sbjct: 513 QEQQKAARARQECLRVTELLGEAERQLHLTRLEKDSIQQSFSNEAKAQALQAQQREQELT 572 Query: 518 Q 520 Q Sbjct: 573 Q 573
>MYSP2_DROME (P35416) Paramyosin, short form (Miniparamyosin)| Length = 640 Score = 39.7 bits (91), Expect = 0.008 Identities = 49/225 (21%), Positives = 94/225 (41%), Gaps = 35/225 (15%) Frame = +2 Query: 11 LTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYR---TIANQEEQASVR-------EIKW 160 L + + ++A L +L EVR L++A R T+ Q E+A+ R + Sbjct: 355 LQATLDQYAVAQRRLAGLNGELEEVRSHLDSANRAKRTVELQYEEAASRINELTTANVSL 414 Query: 161 DAYKTYSADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKN---KVAEESEKLALVNT-- 325 + K+ +L V E+ ++ D++ Q+ ++ K+ +V EE E++ + T Sbjct: 415 VSIKSKLEQELSVVASDYEEVSKELRISDERYQKVQVELKHVVEQVHEEQERIVKLETIK 474 Query: 326 -----------------QLNKLTQNVSKSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVS 454 +LN + + +++E +++DLE +L+ + E K Sbjct: 475 KSLEVEVKNLSIRLEEVELNAVAGSKRIISKLEARIRDLELELEEEKRRHAETIKILRKK 534 Query: 455 TRSREFSLDSLTPQNKEQDLSQ---APSTASVNPAQQQLREPSGI 580 R+ + L K L Q STA +N ++QL E G+ Sbjct: 535 ERTVKEVLVQCEEDQKNLILLQDALDKSTAKINIYRRQLSEQEGV 579
>MYH11_MOUSE (O08638) Myosin-11 (Myosin heavy chain, smooth muscle isoform)| (SMMHC) Length = 1972 Score = 39.7 bits (91), Expect = 0.008 Identities = 42/189 (22%), Positives = 85/189 (44%), Gaps = 3/189 (1%) Frame = +2 Query: 11 LTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQ 190 L + ++ NL K + E + E+ L+ ++ QE + R+++ DA + +Q Sbjct: 1015 LAEEEEKAKNLTKLKSKHESMISELEVRLKKEEKS--RQELEKLKRKLEGDASDFH--EQ 1070 Query: 191 LEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEM 370 + Q AEL++Q++ +++LQ A +A E++A N L K+ E+ Sbjct: 1071 IADLQAQIAELKMQLAKKEEELQAA-------LARLDEEIAQKNNALKKIR-------EL 1116 Query: 371 EKKVQDLEQKL---QLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQAPSTASV 541 E + DL++ L + A +K+++Q +D + + L+ Q +A V Sbjct: 1117 EGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEV 1176 Query: 542 NPAQQQLRE 568 ++ L E Sbjct: 1177 TVLKKALDE 1185 Score = 38.5 bits (88), Expect = 0.017 Identities = 43/192 (22%), Positives = 80/192 (41%), Gaps = 4/192 (2%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSA 184 E L S + L EK +LE ++ ++ +ELE + ++ ++ + A Sbjct: 1715 EELASSLSGRNTLQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATLQAEQLSNELA 1774 Query: 185 DQLEVAQKHAA---ELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVS 355 + AQK+ + +LE Q L +LQE E K K+ +A + ++ +L + V Sbjct: 1775 TERSTAQKNESARQQLERQNKELRSKLQEVEGAVKAKL---KSTVAALEAKIAQLEEQVE 1831 Query: 356 KSA-EMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQAPST 532 + A E + + L+QK D++ K+ ++ + Q KEQ Sbjct: 1832 QEAREKQAATKSLKQK--------DKKLKEVLLQVEDER----KMAEQYKEQ---AEKGN 1876 Query: 533 ASVNPAQQQLRE 568 V ++QL E Sbjct: 1877 TKVKQLKRQLEE 1888 Score = 37.7 bits (86), Expect = 0.029 Identities = 51/217 (23%), Positives = 94/217 (43%), Gaps = 8/217 (3%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSA 184 E L S+ +K L ++L ++ ELE + A Q+E + RE Sbjct: 1125 EDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKRE----------- 1173 Query: 185 DQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSA 364 ++ V +K L+ + + + Q+QE + V E +E+L Q + N+ KS Sbjct: 1174 QEVTVLKK---ALDEETRSHEAQVQEMRQKHTQAVEELTEQL----EQFKRAKANLDKSK 1226 Query: 365 E-MEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSR-EFSLDSLTPQNKEQDLSQAPSTAS 538 + +EK+ DL +L++ QAK V + + E L L + + + ++A + Sbjct: 1227 QTLEKENADLAGELRVL-----GQAKQEVEHKKKKLEVQLQDLQSKCSDGERARAELSDK 1281 Query: 539 VNPAQQQLREPSGIM------AFKFILGVALLVSSLR 631 V+ Q ++ +G++ A K VA L S L+ Sbjct: 1282 VHKLQNEVESVTGMLNEAEGKAIKLAKDVASLGSQLQ 1318 Score = 33.9 bits (76), Expect = 0.42 Identities = 30/163 (18%), Positives = 74/163 (45%), Gaps = 10/163 (6%) Frame = +2 Query: 11 LTSKMQEHANLVHEKDQL-------EQQLLEVRKELEAAYRTIANQEEQASVREIKWDAY 169 L ++Q L E +++ +Q+L E+ E+EA ++ +Q K Sbjct: 892 LQEQLQAETELYAESEEMRVRLAAKKQELEEILHEMEARLEEEEDRRQQLQAERKKMAQQ 951 Query: 170 KTYSADQLEVAQKHAAELEVQVSALDQQLQEAE---IHYKNKVAEESEKLALVNTQLNKL 340 +QLE + +L+++ + ++++ E + ++ ++ S++ L+ +++ L Sbjct: 952 MLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDDILVMDDQNSKLSKERKLLEERVSDL 1011 Query: 341 TQNVSKSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSRE 469 T N+++ E K + L+ K + S+ + + K S + E Sbjct: 1012 TTNLAEEEEKAKNLTKLKSKHESMISELEVRLKKEEKSRQELE 1054
>MYSS_CYPCA (Q90339) Myosin heavy chain, fast skeletal muscle| Length = 1935 Score = 39.7 bits (91), Expect = 0.008 Identities = 47/201 (23%), Positives = 86/201 (42%), Gaps = 13/201 (6%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSA 184 E + ++ A + ++ L ++L E+ + LE A A Q E RE ++ + Sbjct: 1121 EEIEAERAARAKVEKQRADLSRELEEISERLEEAGGATAAQIEMNKKREAEFQKMRRDLE 1180 Query: 185 DQLEVAQKHAAELEVQ----VSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNV 352 + + AA L + V+ L +Q+ + K K+ +E + + L + V Sbjct: 1181 ESTLQHEATAAALRKEQADSVAELGEQIDNLQ-RVKQKLEKEKSEYKMEIDDLTSNMEAV 1239 Query: 353 SKS-AEMEKKVQDLEQKLQLAYSKSDE--------QAKDAVVSTRSREFSLDSLTPQNKE 505 +K+ A +EK + LE +L +KSDE A+ A + T + EFS Q +E Sbjct: 1240 AKAKANLEKMCRTLEDQLSEIKTKSDENVRQLNDMNAQRARLQTENGEFS-----RQLEE 1294 Query: 506 QDLSQAPSTASVNPAQQQLRE 568 ++ + T QQ+ E Sbjct: 1295 KEALVSQLTRGKQAYTQQIEE 1315 Score = 37.7 bits (86), Expect = 0.029 Identities = 52/208 (25%), Positives = 92/208 (44%), Gaps = 33/208 (15%) Frame = +2 Query: 29 EHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQK 208 ++ +L++ K +LE L++V+ E++ A + N EE+A ++ DA A++L+ Q Sbjct: 1720 QNTSLINTKKKLEADLVQVQGEVDDAVQEARNAEEKA--KKAITDA--AMMAEELKKEQD 1775 Query: 209 HAAELE-------VQVSALDQQLQEAEI-----------HYKNKVAE-----ESEK---- 307 +A LE V V L +L EAE +++V E E+E+ Sbjct: 1776 TSAHLERMKKNLEVTVKDLQHRLDEAESLAMKGGKKQLQKLESRVRELEAEVEAEQRRGA 1835 Query: 308 -----LALVNTQLNKLTQNVSKSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREF 472 + ++ +LT + + ++QDL KLQL QA++A T + Sbjct: 1836 DAVKGVRKYERRVKELTYQTEEDKKNVIRLQDLVDKLQLKVKVYKRQAEEAEEQTNTH-- 1893 Query: 473 SLDSLTPQNKEQ-DLSQAPSTASVNPAQ 553 L+ K Q +L +A A V +Q Sbjct: 1894 ----LSRYRKVQHELEEAQERADVAESQ 1917 Score = 32.7 bits (73), Expect = 0.94 Identities = 44/154 (28%), Positives = 70/154 (45%), Gaps = 5/154 (3%) Frame = +2 Query: 188 QLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKV---AEESEKLALVNTQLNKLTQNVSK 358 QL A + AAE + Q+ + QL++A++H V + E++A+V + N L Q Sbjct: 1629 QLSHANRQAAEAQKQLRNVQGQLKDAQLHLDEAVRGQEDMKEQVAMVERR-NSLMQ---- 1683 Query: 359 SAEMEKKVQDLEQKLQLAYSKSDE--QAKDAVVSTRSREFSLDSLTPQNKEQDLSQAPST 532 AE+E+ LEQ + E A + V S+ SL + T + E DL Q Sbjct: 1684 -AEIEELRAALEQTERGRKVAEQELVDASERVGLLHSQNTSLIN-TKKKLEADLVQV--Q 1739 Query: 533 ASVNPAQQQLREPSGIMAFKFILGVALLVSSLRR 634 V+ A Q+ R A K I A++ L++ Sbjct: 1740 GEVDDAVQEARNAEE-KAKKAITDAAMMAEELKK 1772
>SMC1_YEAST (P32908) Structural maintenance of chromosome 1 (DA-box protein SMC1)| Length = 1225 Score = 39.7 bits (91), Expect = 0.008 Identities = 38/172 (22%), Positives = 82/172 (47%), Gaps = 12/172 (6%) Frame = +2 Query: 20 KMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQ-EEQASVREIKWDAYKTYSADQLE 196 +++ H +L+ + +++ ++ E++K+L+ T N +E+ +++ + + + ++ Sbjct: 744 EIKYHNDLIEK--EIQPKITELKKKLDDLENTKDNLVKEKEALQNNIFKEFTSKIGFTIK 801 Query: 197 VAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVS------K 358 + H+ EL Q S QQLQ+ + +NK+ E+++L+ + K +++ K Sbjct: 802 EYENHSGELMRQQSKELQQLQKQILTVENKLQFETDRLSTTQRRYEKAQKDLENAQVEMK 861 Query: 359 SAE-----MEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQN 499 S E +E K+ +E KL+ + DE K V S D L N Sbjct: 862 SLEEQEYAIEMKIGSIESKLEEHKNHLDELQKKFVTKQSELNSSEDILEDMN 913 Score = 33.5 bits (75), Expect = 0.55 Identities = 42/179 (23%), Positives = 80/179 (44%), Gaps = 12/179 (6%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSA 184 E+L +Q V ++ E QL V + EA I ++ + KTY+ Sbjct: 334 ESLQKDLQRQKTYV---ERFETQLKVVTRSKEAFEEEIKQSARNYDKFKLNENDLKTYNC 390 Query: 185 DQLEVAQKHAAELEVQVSALDQQLQEA--EIHYKNKVAEES-----EKLAL----VNTQL 331 + + + LE +++ L+ +E E+ NK A+ S E+L++ ++TQL Sbjct: 391 LHEKYLTEGGSILEEKIAVLNNDKREIQEELERFNKRADISKRRITEELSITGEKLDTQL 450 Query: 332 NKLTQNVS-KSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKE 505 N L +++ K+A +++ +L +KLQ ++ Q D R +D L+ +E Sbjct: 451 NDLRVSLNEKNALHTERLHEL-KKLQSDIESANNQEYDLNFKLRETLVKIDDLSANQRE 508
>MLP1_YEAST (Q02455) Protein MLP1 (Myosin-like protein 1)| Length = 1875 Score = 39.7 bits (91), Expect = 0.008 Identities = 45/224 (20%), Positives = 103/224 (45%), Gaps = 38/224 (16%) Frame = +2 Query: 23 MQEHANLVH-EKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEV 199 +++H L + ++LE ++ +++ELE N+E Q + E K++ + + ++L+ Sbjct: 1290 LEKHEQLSSSDYEKLESEIENLKEELE-------NKERQGAEAEEKFNRLRRQAQERLKT 1342 Query: 200 AQKHAAELEVQVSALD-----------------QQLQEAEIHYKN-------KVAEESEK 307 ++ L QV++L ++LQ A++ N K+ E++EK Sbjct: 1343 SKLSQDSLTEQVNSLRDAKNVLENSLSEANARIEELQNAKVAQGNNQLEAIRKLQEDAEK 1402 Query: 308 LA------------LVNTQLNKLTQNVSKSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVV 451 + + +N L + ++ E +K + ++Q+LQ A S +++ +V Sbjct: 1403 ASRELQAKLEESTTSYESTINGLNEEITTLKEEIEKQRQIQQQLQ-ATSANEQNDLSNIV 1461 Query: 452 STRSREFSLDSLT-PQNKEQDLSQAPSTASVNPAQQQLREPSGI 580 + + F D + + K Q++++ + AQ++L +PS I Sbjct: 1462 ESMKKSFEEDKIKFIKEKTQEVNE-----KILEAQERLNQPSNI 1500 Score = 31.2 bits (69), Expect = 2.7 Identities = 40/166 (24%), Positives = 74/166 (44%), Gaps = 12/166 (7%) Frame = +2 Query: 26 QEHANLVHEKDQ-LEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVA 202 ++ + EK Q + +++LE ++ L NQ ++ EIK K S + EV+ Sbjct: 1470 EDKIKFIKEKTQEVNEKILEAQERL--------NQPSNINMEEIK---KKWESEHEQEVS 1518 Query: 203 QKHAAELEVQVSALDQQLQEAEIHYKNKVAE------ESEKLALVNTQLNKLTQN----V 352 QK + AL ++++ NK+ E E E V ++ + Q+ V Sbjct: 1519 QK----IREAEEALKKRIRLPTEEKINKIIERKKEELEKEFEEKVEERIKSMEQSGEIDV 1574 Query: 353 SKSAEMEKKVQDLEQKLQLAYSKS-DEQAKDAVVSTRSREFSLDSL 487 ++E KVQ+ +++L+ Y+K E+ KD S+ + D L Sbjct: 1575 VLRKQLEAKVQEKQKELENEYNKKLQEELKDVPHSSHISDDERDKL 1620 Score = 29.6 bits (65), Expect = 7.9 Identities = 17/80 (21%), Positives = 36/80 (45%) Frame = +2 Query: 20 KMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEV 199 ++Q+HA++ +L +QL + +++ + E E W + K +QL++ Sbjct: 1046 ELQKHADVSKTISELREQLHTYKGQVKTLNLSRDQLENALKENEKSWSSQKESLLEQLDL 1105 Query: 200 AQKHAAELEVQVSALDQQLQ 259 + +L Q L Q+Q Sbjct: 1106 SNSRIEDLSSQNKLLYDQIQ 1125
>MYH6_MESAU (P13539) Myosin heavy chain, cardiac muscle alpha isoform| (MyHC-alpha) Length = 1939 Score = 39.7 bits (91), Expect = 0.008 Identities = 40/181 (22%), Positives = 83/181 (45%), Gaps = 35/181 (19%) Frame = +2 Query: 29 EHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQAS---------VREIKWDA----- 166 ++ +L+++K ++E L +++ E+E A + N EE+A E+K + Sbjct: 1721 QNTSLINQKKKMEADLTQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAH 1780 Query: 167 ----------------YKTYSADQLEV--AQKHAAELEVQVSALDQQLQEAEIHYKNKVA 292 ++ A+Q+ + +K +LE +V L+ +L EAE + + A Sbjct: 1781 LERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENEL-EAE---QKRNA 1836 Query: 293 EESEKLALVNTQLNKLTQNVSKSAEMEKKVQDLEQKLQL---AYSKSDEQAKDAVVSTRS 463 E + + ++ +LT + + ++QDL KLQL AY + E+A++ + S Sbjct: 1837 ESVKGMRKSERRIKELTYQTEEDKKNLVRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLS 1896 Query: 464 R 466 + Sbjct: 1897 K 1897 Score = 39.7 bits (91), Expect = 0.008 Identities = 39/167 (23%), Positives = 78/167 (46%), Gaps = 3/167 (1%) Frame = +2 Query: 53 KDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKHAA---EL 223 K ++E++L E +E+E A R N + DA + L V +K E+ Sbjct: 1571 KAEIERKLAEKDEEMEQAKR---NHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEM 1627 Query: 224 EVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEMEKKVQDLEQKL 403 E+Q+S ++ EA+ H KN A L +TQL +L + + ++++ + +E++ Sbjct: 1628 EIQLSQANRIASEAQKHLKNAQAH------LKDTQL-QLDDALHANDDLKENIAIVERRN 1680 Query: 404 QLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQAPSTASVN 544 L ++ +E + RSR+ + L ++ L + +T+ +N Sbjct: 1681 TLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLIN 1727
>INVO_AOTTR (P24708) Involucrin| Length = 544 Score = 39.7 bits (91), Expect = 0.008 Identities = 47/192 (24%), Positives = 81/192 (42%), Gaps = 20/192 (10%) Frame = +2 Query: 56 DQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKHAAELEVQV 235 +QLE+QL E ++ E + + QE Q V+ ++ + +Q E KH +LE Q+ Sbjct: 286 EQLEKQL-EHPEQQEGQLKQLEEQEGQ--VKHLEQQEEQLKHLEQQEGQPKHPEQLEKQL 342 Query: 236 SALDQ------QLQEAEIHYKNKVAEESE------------KLALVNTQLNKLTQNVSKS 361 +Q QL+E E K+ +E + L + QL L Q + Sbjct: 343 EHPEQQEGQLKQLEEQEGQVKHLEQQEEQLKHLEQQEGQPKHLEQLEKQLEHLEQQEGQL 402 Query: 362 AEMEKKVQDLE-QKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDL-SQAPSTA 535 +E++ + LE + Q+ SK EQ + + +E L L Q + +L Q Sbjct: 403 KHLEQREEQLELPEQQVGQSKHLEQEEKQLEHPEQQEGQLKHLGKQEAQLELPEQVGQPK 462 Query: 536 SVNPAQQQLREP 571 + ++QL P Sbjct: 463 HLEQQEKQLEHP 474 Score = 37.7 bits (86), Expect = 0.029 Identities = 46/188 (24%), Positives = 76/188 (40%), Gaps = 19/188 (10%) Frame = +2 Query: 56 DQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKHAAELEVQV 235 +QLE+QL E ++ E + + QE Q V+ ++ + +Q E KH +LE Q+ Sbjct: 336 EQLEKQL-EHPEQQEGQLKQLEEQEGQ--VKHLEQQEEQLKHLEQQEGQPKHLEQLEKQL 392 Query: 236 SALDQQ--------LQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEMEKKVQDL 391 L+QQ +E ++ + +S+ L QL Q + + K+ L Sbjct: 393 EHLEQQEGQLKHLEQREEQLELPEQQVGQSKHLEQEEKQLEHPEQQEGQLKHLGKQEAQL 452 Query: 392 EQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQ--------NKEQDLSQ---APSTAS 538 E Q+ K EQ + + +E L Q +E+ L Q AP+ Sbjct: 453 ELPEQVGQPKHLEQQEKQLEHPEQQEGQLKPQEQQEGQLKGLEQQERQLEQPVFAPAPGQ 512 Query: 539 VNPAQQQL 562 V QQ L Sbjct: 513 VQGIQQAL 520 Score = 33.9 bits (76), Expect = 0.42 Identities = 37/147 (25%), Positives = 63/147 (42%), Gaps = 2/147 (1%) Frame = +2 Query: 62 LEQQL--LEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKHAAELEVQV 235 LEQQ LE+ ++ E + + QE + E + K +Q E KH + E QV Sbjct: 166 LEQQEGHLELPEQQEGQLKCLEQQEGHQELPEQQEGQLK--HLEQQEGQLKHLEQQEGQV 223 Query: 236 SALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEMEKKVQDLEQKLQLAY 415 L+QQ +++E+ + + + + L QL L + + +E + LE Q+ Sbjct: 224 KHLEQQEKQSELPEQQR--GQPKYLEQQEGQLKHLEEQKGQLKHLEHQEGQLELPEQVGQ 281 Query: 416 SKSDEQAKDAVVSTRSREFSLDSLTPQ 496 K EQ + + +E L L Q Sbjct: 282 PKHLEQLEKQLEHPEQQEGQLKQLEEQ 308
>MYH14_MOUSE (Q6URW6) Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle| myosin heavy chain IIc) (NMHC II-C) Length = 2000 Score = 39.7 bits (91), Expect = 0.008 Identities = 37/201 (18%), Positives = 86/201 (42%), Gaps = 8/201 (3%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYK---- 172 E L ++ A ++ L ++L +R ELE + Q+E S RE + K Sbjct: 1146 EDLEAERVARAKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKALE 1205 Query: 173 ----TYSADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKL 340 + E+ Q+H+ L L+Q + + K +++ E+E ++ + +L+ L Sbjct: 1206 EESRAHEVSMQELRQRHSQALVEMAEQLEQARRGKGVWEKTRLSLEAE-VSELKAELSSL 1264 Query: 341 TQNVSKSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQ 520 + + + ++++ Q++Q S S+ +A + + L+S++ E + Sbjct: 1265 QTSRQEGEQKRRRLESQLQEVQGRSSDSERARSEAAEKLQRAQAELESVSTALSEAESKA 1324 Query: 521 APSTASVNPAQQQLREPSGIM 583 ++ A+ QL + ++ Sbjct: 1325 IRLGKELSSAESQLHDTQELL 1345 Score = 32.7 bits (73), Expect = 0.94 Identities = 44/202 (21%), Positives = 80/202 (39%), Gaps = 14/202 (6%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQQLLEVRKELEAA----------YRTIANQEEQASVREI 154 E + S A + EK QLE +L ++ +ELE YR + Q E + Sbjct: 1736 EEVASGNLSKAATLEEKRQLEGRLSQLEEELEEEQNNSELLKDHYRKLVLQVESLTT--- 1792 Query: 155 KWDAYKTYSADQLEVAQKHAAELEVQVSALDQQLQE----AEIHYKNKVAEESEKLALVN 322 + A +++SA A+ +LE Q+ L +L E A K +A KLA Sbjct: 1793 ELSAERSFSAK----AESGRQQLERQIQELRARLGEEDAGARARQKMLIAALESKLAQAE 1848 Query: 323 TQLNKLTQNVSKSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNK 502 QL + ++ S ++ ++ + +++ L + A L L Q + Sbjct: 1849 EQLEQESRERILSGKLVRRAEKRLKEVVLQVDEERRVADQVRDQLEKSNLRLKQLKRQLE 1908 Query: 503 EQDLSQAPSTASVNPAQQQLRE 568 E + + + A Q++L + Sbjct: 1909 EAEEEASRAQAGRRRLQRELED 1930
>MYSP1_DROME (P35415) Paramyosin, long form| Length = 879 Score = 39.7 bits (91), Expect = 0.008 Identities = 49/225 (21%), Positives = 94/225 (41%), Gaps = 35/225 (15%) Frame = +2 Query: 11 LTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYR---TIANQEEQASVR-------EIKW 160 L + + ++A L +L EVR L++A R T+ Q E+A+ R + Sbjct: 594 LQATLDQYAVAQRRLAGLNGELEEVRSHLDSANRAKRTVELQYEEAASRINELTTANVSL 653 Query: 161 DAYKTYSADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKN---KVAEESEKLALVNT-- 325 + K+ +L V E+ ++ D++ Q+ ++ K+ +V EE E++ + T Sbjct: 654 VSIKSKLEQELSVVASDYEEVSKELRISDERYQKVQVELKHVVEQVHEEQERIVKLETIK 713 Query: 326 -----------------QLNKLTQNVSKSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVS 454 +LN + + +++E +++DLE +L+ + E K Sbjct: 714 KSLEVEVKNLSIRLEEVELNAVAGSKRIISKLEARIRDLELELEEEKRRHAETIKILRKK 773 Query: 455 TRSREFSLDSLTPQNKEQDLSQ---APSTASVNPAQQQLREPSGI 580 R+ + L K L Q STA +N ++QL E G+ Sbjct: 774 ERTVKEVLVQCEEDQKNLILLQDALDKSTAKINIYRRQLSEQEGV 818 Score = 32.3 bits (72), Expect = 1.2 Identities = 26/95 (27%), Positives = 56/95 (58%), Gaps = 3/95 (3%) Frame = +2 Query: 170 KTYSADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQN 349 ++Y+ +++ V++KH ++LEV +S L+ K+ E + + +++ ++L+Q Sbjct: 165 ESYNKEKI-VSEKHISKLEVSISELNV-----------KIEELNRTVIDISSHRSRLSQ- 211 Query: 350 VSKSAEMEKKVQDLEQKLQ-LAYSKSD--EQAKDA 445 ++ E+ K VQDL+ +L +++SKS Q +DA Sbjct: 212 --ENIELTKDVQDLKVQLDTVSFSKSQVISQLEDA 244
>MYO5B_HUMAN (Q9ULV0) Myosin-5B (Myosin Vb)| Length = 1849 Score = 39.7 bits (91), Expect = 0.008 Identities = 35/147 (23%), Positives = 67/147 (45%), Gaps = 6/147 (4%) Frame = +2 Query: 11 LTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDA-YKTYSAD 187 L + + NLV E QLEQ+ +R E+ +T ++ ++ ++ D+ Y + S Sbjct: 1061 LEEERSRYQNLVKEYSQLEQRYDNLRDEMTIIKQTPGHRRNPSNQSSLESDSNYPSISTS 1120 Query: 188 QL---EVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSK 358 ++ E A + E+ ++ +A+D + + + +V E ++ + QL K Q SK Sbjct: 1121 EIGDTEDALQQVEEIGLEKAAMDMTV---FLKLQKRVRELEQERKKLQVQLEKREQQDSK 1177 Query: 359 SAEMEKKVQ--DLEQKLQLAYSKSDEQ 433 + E DL+ LAY+ Q Sbjct: 1178 KVQAEPPQTDIDLDPNADLAYNSLKRQ 1204
>HOOK1_MOUSE (Q8BIL5) Hook homolog 1| Length = 728 Score = 39.7 bits (91), Expect = 0.008 Identities = 39/173 (22%), Positives = 87/173 (50%), Gaps = 8/173 (4%) Frame = +2 Query: 26 QEHANLVHEKDQLEQQ---LLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLE 196 ++H L+ EK++L +Q L E +EL + + +Q + + A K+Y E Sbjct: 404 EKHETLLKEKERLIEQRDTLKETNEELRCS------KAQQDHLNQADASATKSYENLAAE 457 Query: 197 VAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEE-SEKLALVNTQLNKLT--QNVSKS-- 361 + E+ +++ ++ L+ + +N+ E+ E+L + ++N+L Q +SK Sbjct: 458 IMPVEYREVFIRLQHENKMLRLQQEGTENERIEQLQEQLEQKHRKMNELETEQRLSKERI 517 Query: 362 AEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQ 520 E++++++DL++ LQ SKS+ ++ + + E ++ LT ++E Q Sbjct: 518 GELQQQIEDLQKSLQEQGSKSEGESSSKL--KQKLEAHMEKLTEVHEELQKKQ 568 Score = 31.2 bits (69), Expect = 2.7 Identities = 24/122 (19%), Positives = 59/122 (48%), Gaps = 4/122 (3%) Frame = +2 Query: 80 EVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKHAAELEVQVSALDQQLQ 259 +++++LEA + E+ ++ + + D + AQK +ELE + D+ ++ Sbjct: 545 KLKQKLEAHMEKLTEVHEELQKKQ---ELIEDLQPDISQNAQK-ISELEAALQKKDEDMK 600 Query: 260 EAEIHYKNKVAEESEKLALVNTQLNKLTQNV----SKSAEMEKKVQDLEQKLQLAYSKSD 427 E YK + + + ++ +LN + + + AE E++++ LE + ++A + Sbjct: 601 AMEERYKMYLEKARNVIKTLDPKLNPASAEIMLLRKQLAEKERRIEILESECKVAKLRDY 660 Query: 428 EQ 433 E+ Sbjct: 661 EE 662
>YQ37_SCHPO (Q10432) Hypothetical protein C188.07 in chromosome III| Length = 735 Score = 39.3 bits (90), Expect = 0.010 Identities = 31/111 (27%), Positives = 52/111 (46%), Gaps = 8/111 (7%) Frame = +2 Query: 197 VAQKHAAELEVQVSALDQQLQEAEIHYKNKVAE---ESEKLALVNTQLNKL-TQNVSKSA 364 V Q + ELE Q+S L LQE Y+N V E + EK N L+KL + V + A Sbjct: 539 VQQSRSEELEQQISKLTDNLQE----YRNTVRELKLDLEKSKKKNEDLSKLEVEKVEEIA 594 Query: 365 EMEKKVQDLEQKLQLAYSK----SDEQAKDAVVSTRSREFSLDSLTPQNKE 505 ++K++ L ++ + + S+E + ++ + + L L KE Sbjct: 595 NLKKELTHLAKQQEFGFKYVQEFSNEDLQGKLIEANEKNYKLTQLLKTQKE 645
>SMC4_CAEEL (Q20060) Structural maintenance of chromosome 4 (Protein smc-4)| Length = 1549 Score = 39.3 bits (90), Expect = 0.010 Identities = 54/245 (22%), Positives = 102/245 (41%), Gaps = 49/245 (20%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQQLLEVRKE---------------------LEAAYRTIA 121 E L E L ++ +++ QL+E R++ +E +TIA Sbjct: 794 EKLGKLRDEADELKGQEHEMDGQLIEARRKVAEMSNRLSIVTSSVQSAAPAIETLKKTIA 853 Query: 122 NQEEQASVREIKWDAYKTYSADQL--------------EVAQKHAAELEVQVSALDQQLQ 259 NQE++A+ ++K DA KT Q E A+ A + E+Q S LD + Sbjct: 854 NQEKEAA--KVKVDA-KTLEDKQKIVEELEKKRDELGEEAAKVKARQAEIQ-SKLDGIFK 909 Query: 260 EAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKS-----------AEMEKKVQDLEQKLQ 406 E ++++ E +K + + K T N+S S + +K ++ +++K + Sbjct: 910 ELVQCHRDEAKESLQKRQKLEKDIAKETANISNSGRNIAKCDENISRHDKDIEKMKKKCE 969 Query: 407 LAYSKS--DEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQAPSTASVNPAQQQLREPS-G 577 K+ DE+ K + E + L + +E Q+ +A+ + +L++ S G Sbjct: 970 ELMEKAIDDEEVKSKKETVERFEKQIKKLQTKGEEMTKKQSELSAAETKLEGELKKCSEG 1029 Query: 578 IMAFK 592 I K Sbjct: 1030 IKELK 1034
>PHP_DROME (P39769) Polyhomeotic-proximal chromatin protein| Length = 1589 Score = 39.3 bits (90), Expect = 0.010 Identities = 41/179 (22%), Positives = 78/179 (43%), Gaps = 8/179 (4%) Frame = +2 Query: 65 EQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLE------VAQKHAAELE 226 +QQ+L+ ++ L+ I Q++QA+V+ + + Q+ VAQ+ A + Sbjct: 784 KQQILQQQQMLQQQIAAIQMQQQQAAVQAQQQQQQQVSQQQQVNAQQQQAVAQQQQAVAQ 843 Query: 227 VQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEMEKKVQDLEQKLQ 406 Q +QQ Q A+ A+ + LA Q+ ++ N ++ +++ Q L +L Sbjct: 844 AQQQQREQQQQVAQAQ-----AQHQQALANATQQILQVAPNQFITSHQQQQQQQLHNQLI 898 Query: 407 LAYSKSDEQAK-DAVVSTRSREFSLDSLTPQN-KEQDLSQAPSTASVNPAQQQLREPSG 577 + QA+ A V ++++ QN +Q + Q S +QQQ SG Sbjct: 899 QQQLQQQAQAQVQAQVQAQAQQQQQQREQQQNIIQQIVVQQSGATSQQTSQQQQHHQSG 957
>MYH7_PIG (P79293) Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta)| Length = 1935 Score = 39.3 bits (90), Expect = 0.010 Identities = 40/181 (22%), Positives = 84/181 (46%), Gaps = 35/181 (19%) Frame = +2 Query: 29 EHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQAS---------VREIKWDA----- 166 ++ +L+++K ++E L +++ E+E A + N EE+A E+K + Sbjct: 1719 QNTSLINQKKKMEADLSQLQTEVEEAVQESRNAEEKAKKAITDAAMMAEELKKEQDTSAH 1778 Query: 167 ----------------YKTYSADQLEV--AQKHAAELEVQVSALDQQLQEAEIHYKNKVA 292 ++ A+Q+ + +K +LE +V L+ +L EAE + + A Sbjct: 1779 LERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENEL-EAE---QKRNA 1834 Query: 293 EESEKLALVNTQLNKLTQNVSKSAEMEKKVQDLEQKLQL---AYSKSDEQAKDAVVSTRS 463 E + + ++ +LT + + ++QDL KLQL AY++ E+A++ + S Sbjct: 1835 ESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYNRQAEEAEEQANTNLS 1894 Query: 464 R 466 + Sbjct: 1895 K 1895
>SMC2_CHICK (Q90988) Structural maintenance of chromosome 2 (Chromosome scaffold| protein ScII) Length = 1189 Score = 39.3 bits (90), Expect = 0.010 Identities = 41/171 (23%), Positives = 80/171 (46%), Gaps = 5/171 (2%) Frame = +2 Query: 65 EQQLLEVRKELEAAYRTIANQEEQASVREI---KWDAYKTYSADQLEVAQKHAAELEVQV 235 E +L +LEA + +AN + A + +W+ K+ A+ L+ + +A + Q Sbjct: 685 EDELKIKTSQLEATEKELANLKNMAEKYQHLKQQWEM-KSEEAELLQTKIQQSAYHKQQE 743 Query: 236 SALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEME--KKVQDLEQKLQL 409 L + AE K EES++ A + K +N K+AE E K++++ +QKL Sbjct: 744 DLLALKKTIAECEETLKKTEESQRKA---EEEYKALENKMKNAEAERGKEIKNAQQKLNS 800 Query: 410 AYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQAPSTASVNPAQQQL 562 A K+D+ ++ + ++ +++L + ++ QA AQQ + Sbjct: 801 AKKKADDSSR----KMKEKQQEVEALVLELEQLKQEQASYKQQSEAAQQAI 847
>MYSP_ECHGR (P35417) Paramyosin| Length = 863 Score = 39.3 bits (90), Expect = 0.010 Identities = 46/168 (27%), Positives = 76/168 (45%), Gaps = 18/168 (10%) Frame = +2 Query: 41 LVHEKDQLEQQLLEVRKELE----AAYRTIANQEEQASVREIKWDA-----YKTYSAD-- 187 L H K ++EQ+L E +ELE + RTI S E+++ + K Y A Sbjct: 477 LNHLKSEMEQRLREKDEELENLRKSTTRTIEELTTTISEMEVRFKSDMSRLKKKYEATIS 536 Query: 188 ----QLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVS 355 QL+VA K A L + AL Q++QE + A E E+ A + N L + Sbjct: 537 ELEVQLDVANKANASLNRENKALAQRVQELQ------TALEDERRAREAAESN-LQVSER 589 Query: 356 KSAEMEKKVQDLEQKLQL---AYSKSDEQAKDAVVSTRSREFSLDSLT 490 K + +V+++ +L+L A ++ + DA S+++LT Sbjct: 590 KRIALTSEVEEIRSQLELSDRARKNAESELNDANGRISELTMSVNTLT 637
>MYO3_SCHPO (O14157) Myosin type-2 heavy chain 2 (Myosin type II heavy chain 2)| Length = 2104 Score = 39.3 bits (90), Expect = 0.010 Identities = 44/213 (20%), Positives = 92/213 (43%), Gaps = 27/213 (12%) Frame = +2 Query: 11 LTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWD---AYK--- 172 LT+ +QE L HEKD L ++ +E + +++ E Q ++ + K++ A K Sbjct: 872 LTNDLQEEQALAHEKDILVER---ANSRVEVVHERLSSLENQVTIADEKYEFLYAEKQSI 928 Query: 173 -----------TYSADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAE---ESEKL 310 +Y +D +K + ++ + + +E E Y N +A+ S+ L Sbjct: 929 EEDLANKQTEISYLSDLSSTLEKKLSSIKKDEQTISSKYKELEKDYLNIMADYQHSSQHL 988 Query: 311 ALVNTQLNKLTQNVSKSAEMEKKVQDLEQKL---QLAYSKSDEQAKDAVVS----TRSRE 469 + + +N+ N+ E+ +K+ L+ +L Q +Y ++ ++ S R+ E Sbjct: 989 SNLEKAINEKNLNI---RELNEKLMRLDDELLLKQRSYDTKVQELREENASLKDQCRTYE 1045 Query: 470 FSLDSLTPQNKEQDLSQAPSTASVNPAQQQLRE 568 L SL + E + A + Q+++ E Sbjct: 1046 SQLASLVSKYSETESELNKKEAELVIFQKEITE 1078
>K2C4_HUMAN (P19013) Keratin, type II cytoskeletal 4 (Cytokeratin-4) (CK-4)| (Keratin-4) (K4) Length = 534 Score = 39.3 bits (90), Expect = 0.010 Identities = 48/233 (20%), Positives = 97/233 (41%), Gaps = 30/233 (12%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSA 184 E +K +E N ++ E + ++K+++AAY E + + + K Sbjct: 235 EDFKTKYEEEIN---KRTAAENDFVVLKKDVDAAYLNKVELEAKVDSLNDEINFLKVLYD 291 Query: 185 DQLEVAQKHAAELEVQVSA-------LDQQLQEAEIHYKNKVAEES--EKLALVNTQLNK 337 +L Q H ++ V +S LD + E Y+ ++A+ S E AL T++ + Sbjct: 292 AELSQMQTHVSDTSVVLSMDNNRNLDLDSIIAEVRAQYE-EIAQRSKAEAEALYQTKVQQ 350 Query: 338 LTQNV-----------SKSAEMEKKVQDLE----------QKLQLAYSKSDEQAKDAVVS 454 L +V S+ AE+ + +Q L Q LQ++ + ++++ ++A+ Sbjct: 351 LQISVDQHGDNLKNTKSEIAELNRMIQRLRAEIENIKKQCQTLQVSVADAEQRGENALKD 410 Query: 455 TRSREFSLDSLTPQNKEQDLSQAPSTASVNPAQQQLREPSGIMAFKFILGVAL 613 S+ L++ Q KE+ + LRE +M+ K L + + Sbjct: 411 AHSKRVELEAALQQAKEE-------------LARMLREYQELMSVKLALDIEI 450
>TPM4_PIG (P67937) Tropomyosin alpha-4 chain (Tropomyosin-4)| Length = 247 Score = 39.3 bits (90), Expect = 0.010 Identities = 31/122 (25%), Positives = 55/122 (45%) Frame = +2 Query: 47 HEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKHAAELE 226 H ++ +++ EV ++L + EE+A V E+K LE K+ Sbjct: 116 HIAEEADRKYEEVARKLVILEGELERAEERAEVSELK--------CGDLEEELKNVTNNL 167 Query: 227 VQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEMEKKVQDLEQKLQ 406 + A ++ E E Y+ ++ S+KL T+ + V+K +EK + DLE+KL Sbjct: 168 KSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAK---LEKTIDDLEEKLA 224 Query: 407 LA 412 A Sbjct: 225 QA 226
>TPM4_HUMAN (P67936) Tropomyosin alpha-4 chain (Tropomyosin-4) (TM30p1)| Length = 247 Score = 39.3 bits (90), Expect = 0.010 Identities = 31/122 (25%), Positives = 55/122 (45%) Frame = +2 Query: 47 HEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKHAAELE 226 H ++ +++ EV ++L + EE+A V E+K LE K+ Sbjct: 116 HIAEEADRKYEEVARKLVILEGELERAEERAEVSELK--------CGDLEEELKNVTNNL 167 Query: 227 VQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEMEKKVQDLEQKLQ 406 + A ++ E E Y+ ++ S+KL T+ + V+K +EK + DLE+KL Sbjct: 168 KSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAK---LEKTIDDLEEKLA 224 Query: 407 LA 412 A Sbjct: 225 QA 226
>TPM4_HORSE (P02561) Tropomyosin alpha-4 chain (Tropomyosin-4) (Platelet beta| tropomyosin) Length = 247 Score = 39.3 bits (90), Expect = 0.010 Identities = 31/122 (25%), Positives = 55/122 (45%) Frame = +2 Query: 47 HEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKHAAELE 226 H ++ +++ EV ++L + EE+A V E+K LE K+ Sbjct: 116 HIAEEADRKYEEVARKLVILEGELERAEERAEVSELK--------CGDLEEELKNVTNNL 167 Query: 227 VQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEMEKKVQDLEQKLQ 406 + A ++ E E Y+ ++ S+KL T+ + V+K +EK + DLE+KL Sbjct: 168 KSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAK---LEKTIDDLEEKLA 224 Query: 407 LA 412 A Sbjct: 225 QA 226
>CTRO_HUMAN (O14578) Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK)| (Rho-interacting, serine/threonine-protein kinase 21) Length = 2027 Score = 39.3 bits (90), Expect = 0.010 Identities = 42/169 (24%), Positives = 79/169 (46%), Gaps = 3/169 (1%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQAS-VREIKWDAYKTYS 181 + L K+++ E +L Q + + ++ E + N+E+ + +R+ K Sbjct: 639 QELQEKLEKAVKASTEATELLQNIRQAKERAERELEKLQNREDSSEGIRK------KLVE 692 Query: 182 ADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNK-LTQNVSK 358 A++LE +KH E QVSA Q E+H K K EK+ +++ Q+ K L + Sbjct: 693 AEELE--EKHR---EAQVSA-----QHLEVHLKQKEQHYEEKIKVLDNQIKKDLADKETL 742 Query: 359 SAEMEKKVQDLEQKLQ-LAYSKSDEQAKDAVVSTRSREFSLDSLTPQNK 502 M++ ++ +K + L+ K+ A D+ + RS E + L+ NK Sbjct: 743 ENMMQRHEEEAHEKGKILSEQKAMINAMDSKI--RSLEQRIVELSEANK 789
>MYH6_HUMAN (P13533) Myosin heavy chain, cardiac muscle alpha isoform| (MyHC-alpha) Length = 1939 Score = 39.3 bits (90), Expect = 0.010 Identities = 40/181 (22%), Positives = 83/181 (45%), Gaps = 35/181 (19%) Frame = +2 Query: 29 EHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQAS---------VREIKWDA----- 166 ++ +L+++K ++E L +++ E+E A + N EE+A E+K + Sbjct: 1721 QNTSLINQKKKMEADLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAH 1780 Query: 167 ----------------YKTYSADQLEV--AQKHAAELEVQVSALDQQLQEAEIHYKNKVA 292 ++ A+Q+ + +K +LE +V L+ +L EAE + + A Sbjct: 1781 LERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGEL-EAE---QKRNA 1836 Query: 293 EESEKLALVNTQLNKLTQNVSKSAEMEKKVQDLEQKLQL---AYSKSDEQAKDAVVSTRS 463 E + + ++ +LT + + ++QDL KLQL AY + E+A++ + S Sbjct: 1837 ESVKGMRKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLS 1896 Query: 464 R 466 + Sbjct: 1897 K 1897
>NUMA1_HUMAN (Q14980) Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H| antigen) Length = 2115 Score = 39.3 bits (90), Expect = 0.010 Identities = 47/198 (23%), Positives = 81/198 (40%), Gaps = 27/198 (13%) Frame = +2 Query: 8 ALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQAS------VREI----- 154 +LTS++ + ++DQ L + KE +A Q+EQAS V ++ Sbjct: 502 SLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQQQEQASQGLRHQVEQLSSSLK 561 Query: 155 -KWDAYKTYSADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESE---KLALVN 322 K K + Q Q HA +L + L+E + K A E E KL ++ Sbjct: 562 QKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQLEALEKEKAAKLEILQ 621 Query: 323 TQL-----------NKLTQNVSKSAEMEKKVQDLEQKLQLAYSKSDE-QAKDAVVSTRSR 466 QL +TQ + AE+ +KV++L+ ++ A + E QA+ A + + R Sbjct: 622 QQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLR 681 Query: 467 EFSLDSLTPQNKEQDLSQ 520 + + Q+ Q Sbjct: 682 SEQQKATEKERVAQEKDQ 699 Score = 31.6 bits (70), Expect = 2.1 Identities = 50/177 (28%), Positives = 76/177 (42%), Gaps = 4/177 (2%) Frame = +2 Query: 50 EKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKHAAELEV 229 E+ L +Q LEV EL+ A +E A+VR DA +T A+ AQ A ELEV Sbjct: 1456 ERANLGRQFLEV--ELDQAREKYV--QELAAVRA---DA-ETRLAEVQREAQSTARELEV 1507 Query: 230 QVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSK----SAEMEKKVQDLEQ 397 + + K KV EE ++ + KLT V + E K+V++L + Sbjct: 1508 MTAKYEGA--------KVKVLEERQRF---QEERQKLTAQVEQLEVFQREQTKQVEELSK 1556 Query: 398 KLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQAPSTASVNPAQQQLRE 568 KL + SD+ +K ++ L ++ Q E A +N Q QL + Sbjct: 1557 KL----ADSDQASK-------VQQQKLKAVQAQGGESQQEAQRLQAQLNELQAQLSQ 1602
>Y4393_ANASP (Q05070) Hypothetical protein alr4393 precursor| Length = 496 Score = 39.3 bits (90), Expect = 0.010 Identities = 43/179 (24%), Positives = 78/179 (43%), Gaps = 10/179 (5%) Frame = +2 Query: 14 TSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAY-KTYSADQ 190 T + + +A +Q +++L ++ +E R +AN+++ R+ K K Sbjct: 188 TERRRLYAEAKKAIEQRDRELANRQQAIEQRDRELANRQQALQQRDQKISQLDKIIQNRN 247 Query: 191 LEVAQKHAA---------ELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLT 343 LE+AQ+ ELE Q L+Q++ E +Y++ KLALV Q+ L Sbjct: 248 LEIAQREEVIAKRESRLKELETQQDYLEQEVARLEKYYQSYRDLRLGKLALVRGQV--LA 305 Query: 344 QNVSKSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQ 520 V ++ ++ Q + Q LQ A + + + + S L +TP EQ + Q Sbjct: 306 SAVIRTNQVAATRQIIIQLLQEANRNASLELSEP--GSNSANIELLRITPDRIEQLIQQ 362
>TAXB1_BOVIN (Q2KJE0) Tax1-binding protein 1 homolog| Length = 817 Score = 39.3 bits (90), Expect = 0.010 Identities = 48/186 (25%), Positives = 79/186 (42%), Gaps = 5/186 (2%) Frame = +2 Query: 26 QEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQ 205 +E ++ V+ +D+ L E E + + + + + + D KT D LE Sbjct: 375 KELSDAVNVRDKTMADLHTAHLENEKVKKQLTDALAELKLSAVNKDQEKT---DTLE--- 428 Query: 206 KHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEMEKKVQ 385 EL +V L +LQ A HYK K +E ++L Q+NKL+ + S + K Sbjct: 429 ---HELRREVEDLKLRLQMAADHYKEKF-KECQRL---QKQINKLSDQSANSNSVFTKKI 481 Query: 386 DLEQKLQLAYSKSDEQAKDAVVSTR----SREFSLDSLTP-QNKEQDLSQAPSTASVNPA 550 +QK+ A +D A + V + + E D+LT Q E A T N Sbjct: 482 GSQQKVNDASINTDPAATASTVDVKPLPSTAETDFDNLTKGQVSEMTKEIADKTEKYNKC 541 Query: 551 QQQLRE 568 +Q L++ Sbjct: 542 KQLLQD 547
>CEP57_BOVIN (Q865V0) Centrosomal protein of 57 kDa (Cep57 protein)| (Testis-specific protein 57) (Translokin) Length = 499 Score = 38.9 bits (89), Expect = 0.013 Identities = 32/80 (40%), Positives = 46/80 (57%), Gaps = 1/80 (1%) Frame = +2 Query: 221 LEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEMEKKVQDLEQK 400 LE QVS L+++ Q + H +N++ EKL L+ + NKLT + A EKK+Q+LE K Sbjct: 165 LEKQVS-LERERQHDQTHVQNQL----EKLDLLEQEYNKLT---TMQALAEKKMQELEAK 216 Query: 401 L-QLAYSKSDEQAKDAVVST 457 L Q + QAK A + T Sbjct: 217 LRQEEQERKRMQAKAAQLQT 236
>TPM_HALDV (Q9GZ71) Tropomyosin| Length = 284 Score = 38.9 bits (89), Expect = 0.013 Identities = 41/153 (26%), Positives = 71/153 (46%), Gaps = 3/153 (1%) Frame = +2 Query: 56 DQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKHAAELEVQV 235 D +++++L ++ E E A A Q EQ +R+ + K + L QK A LE Sbjct: 2 DAIKKKMLAMKMEKENAVDR-AEQNEQ-KLRDT--EEQKAKIEEDLNNLQKKCANLENDF 57 Query: 236 SALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEMEKKVQDLEQKLQLAY 415 +++QLQEA + +E V+ K+T E+++Q ++L+ A Sbjct: 58 DNVNEQLQEAMAKLETSEKRVTEMEQEVSGTTRKITLLEEDLERNEERLQTATERLEEAS 117 Query: 416 SKSDEQAKDA-VVSTRS--REFSLDSLTPQNKE 505 +DE + A V+ +RS + +D L Q KE Sbjct: 118 KAADESERGARVLESRSLADDERIDQLEAQLKE 150
>EP15_HUMAN (P42566) Epidermal growth factor receptor substrate 15 (Protein| Eps15) (AF-1p protein) Length = 896 Score = 38.9 bits (89), Expect = 0.013 Identities = 32/110 (29%), Positives = 54/110 (49%), Gaps = 12/110 (10%) Frame = +2 Query: 41 LVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSA---DQLEVAQKH 211 L +K QLE+QL EVRK+ + I++ + + + +E + Y+ A ++L Q+ Sbjct: 401 LDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQE 460 Query: 212 AAELEVQVSALDQQLQEAEIHYKNKVAE---------ESEKLALVNTQLN 334 AELE V + QL+ + H ++ E E + L N+QLN Sbjct: 461 TAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKDLENHNSQLN 510
>CALD1_HUMAN (Q05682) Caldesmon (CDM)| Length = 793 Score = 38.9 bits (89), Expect = 0.013 Identities = 40/156 (25%), Positives = 70/156 (44%), Gaps = 4/156 (2%) Frame = +2 Query: 50 EKDQLEQQLLEVRKELEAAYRTIANQEEQASVRE-IKWDAYKTYSADQ-LEVAQKHAAEL 223 E ++ E+ E ++ E R ++ A R+ IK + + Q ++ +K AAE Sbjct: 310 EAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEE 369 Query: 224 EVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQL--NKLTQNVSKSAEMEKKVQDLEQ 397 + A +++ + E +NK EE +K A+ T++ K+ Q + EKK Q E Sbjct: 370 RQRARAEEEEKAKVEEQKRNKQLEE-KKRAMQETKIKGEKVEQKIEGKWVNEKKAQ--ED 426 Query: 398 KLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKE 505 KLQ A K + K V + + D T + +E Sbjct: 427 KLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEE 462
>PLEC1_RAT (P30427) Plectin-1 (PLTN) (PCN)| Length = 4687 Score = 38.9 bits (89), Expect = 0.013 Identities = 28/132 (21%), Positives = 63/132 (47%), Gaps = 20/132 (15%) Frame = +2 Query: 53 KDQLEQQLLEVRKELEAAYRTIANQEEQASV------------REIKWDAYKTYSADQLE 196 ++Q E++ + RK++E A R + EEQA +E + +A + A+Q Sbjct: 2237 REQAEREAAQSRKQVEEAERLKQSAEEQAQAQAQAQAAAEKLRKEAEQEAARRAQAEQAA 2296 Query: 197 VAQKHAAELEV--------QVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNV 352 + QK AA+ E+ Q Q+++ + ++ E + ++++ +L +L V Sbjct: 2297 LKQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKSILDEELQRLKAEV 2356 Query: 353 SKSAEMEKKVQD 388 +++A +V++ Sbjct: 2357 TEAARQRSQVEE 2368 Score = 37.7 bits (86), Expect = 0.029 Identities = 36/151 (23%), Positives = 69/151 (45%), Gaps = 4/151 (2%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSA 184 E +T + + + +K ++++L +R+ EA + A Q E A ++ + Sbjct: 1539 EEVTRREEAAVDAQQQKRSIQEELQHLRQSSEAEIQAKAQQVEAAERSRMRIEEEIRVVR 1598 Query: 185 DQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKL-ALVNTQLNKLTQNVSKS 361 QLE ++ E ++ AL + +EAE K + EE+E+L V + + Q ++ Sbjct: 1599 LQLETTERQRGGAEDELQALRARAEEAEAQ-KRQAQEEAERLRRQVQDESQRKRQAEAEL 1657 Query: 362 AEMEKKVQDLEQKLQLAYSKSDE---QAKDA 445 A K + ++ Q A DE QA++A Sbjct: 1658 ALRVKAEAEAAREKQRALQALDELKLQAEEA 1688 Score = 35.8 bits (81), Expect = 0.11 Identities = 48/187 (25%), Positives = 79/187 (42%), Gaps = 10/187 (5%) Frame = +2 Query: 47 HEKDQLEQQLLEVRKEL-EAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKHAAEL 223 H+K L+++L ++ E+ EAA + +EE SVR Q+E K A + Sbjct: 2340 HQKSILDEELQRLKAEVTEAARQRSQVEEELFSVRV------------QMEELGKLKARI 2387 Query: 224 EVQVSAL-------DQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEMEKKV 382 E + AL Q+ E E +VAEE+ +L++ + +L Q Sbjct: 2388 EAENRALILRDKDNTQRFLEEEAEKMKQVAEEAARLSVAAQEAARLRQLAE--------- 2438 Query: 383 QDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKE--QDLSQAPSTASVNPAQQ 556 +DL Q+ LA E+ + +TR + + L Q KE Q+ ++ AQQ Sbjct: 2439 EDLAQQRALAEKMLKEKMQAVQEATRLKAEA--ELLQQQKELAQEQARRLQADKEQMAQQ 2496 Query: 557 QLREPSG 577 + E G Sbjct: 2497 LVEETQG 2503 Score = 32.0 bits (71), Expect = 1.6 Identities = 48/212 (22%), Positives = 80/212 (37%), Gaps = 16/212 (7%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSA 184 E L E ++ +LE +L +VR E+E + A EE++ K S Sbjct: 1874 EELARLQHEATAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEK-------SK 1926 Query: 185 DQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEE-------------SEKLALVN- 322 +LE EL + + L +EA H ++AEE +EKLA ++ Sbjct: 1927 QRLEAEAGRFRELAEEAARLRALAEEARRH--RELAEEDAARQRAEADGVLTEKLAAISE 1984 Query: 323 -TQLNKLTQNVSKSAEME-KKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQ 496 T+L + K E E ++++ L + + +EQA R L + Sbjct: 1985 ATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASES 2044 Query: 497 NKEQDLSQAPSTASVNPAQQQLREPSGIMAFK 592 E+ T +Q+ + IMA K Sbjct: 2045 ELERQKGLVEDT-----LRQRRQVEEEIMALK 2071
>RAD50_AERPE (Q9YFZ1) DNA double-strand break repair rad50 ATPase| Length = 919 Score = 38.9 bits (89), Expect = 0.013 Identities = 28/118 (23%), Positives = 57/118 (48%), Gaps = 7/118 (5%) Frame = +2 Query: 95 LEAAYRTIANQEEQASVREIKWDAYKTYSAD-QLEVAQKHAAELEVQVSALDQQLQEAE- 268 L++ Y T+ N E REI+ + + + + E ++ A +LE + AL ++ + E Sbjct: 203 LQSGYMTLRN-EVLGVDREIREASKRLEELEREREELERRARDLESEAKALQSEIGKLET 261 Query: 269 -----IHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEMEKKVQDLEQKLQLAYSKSD 427 ++ + + E KL +NT+L +S ++EK+ +L K LA+ ++ Sbjct: 262 MEEMLVNVTSMIRSERSKLDTINTRLRYAESKISSIDDLEKRRAELRAKASLAHEVAE 319
>PLCB1_BOVIN (P10894) 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase| beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C-beta-1) (PLC-beta-1) (PLC-I) (PLC-154) Length = 1216 Score = 38.9 bits (89), Expect = 0.013 Identities = 37/152 (24%), Positives = 76/152 (50%), Gaps = 8/152 (5%) Frame = +2 Query: 8 ALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSAD 187 AL ++M + LV KD+ +QQLL +R+E + + + + ++++ D + + Sbjct: 996 ALDAEMTQ--KLVDLKDKQQQQLLNLRQEQYYSEKYQKREHIKLLIQKLT-DVAEECQNN 1052 Query: 188 QL----EVAQKHAAELEVQVSALDQQLQE--AEIHYKNKVAEESEKLALVNTQLNKLTQN 349 QL E+ +K EL+ +D++ QE E K+K E EK ++ + + ++ Q Sbjct: 1053 QLKKLKEICEKEKKELK---KKMDKKRQEKITEAKSKDKSQMEEEKTEMIRSYIQEVVQY 1109 Query: 350 VSKSAEMEKKVQD--LEQKLQLAYSKSDEQAK 439 + + E + K Q+ +E+ ++ DE+ K Sbjct: 1110 IKRLEEAQSKRQEKLVEKHKEIRQQILDEKPK 1141
>CENPE_HUMAN (Q02224) Centromeric protein E (CENP-E protein)| Length = 2663 Score = 38.9 bits (89), Expect = 0.013 Identities = 42/155 (27%), Positives = 76/155 (49%), Gaps = 16/155 (10%) Frame = +2 Query: 11 LTSKMQEHANLVHEKDQLEQQL---------LEVRKELEAAYRTIANQEEQASVREIKWD 163 L + E V E +QL++Q+ LE+ + L A N EE SV + + + Sbjct: 1835 LKKDVNETQKKVSEMEQLKKQIKDQSLTLSKLEI-ENLNLAQELHENLEEMKSVMKERDN 1893 Query: 164 AYKTYSADQLEVAQKHAAELEVQVSALD--QQLQEAEI---HYKNKVAEESEKLALVNTQ 328 + +LE Q + E + L+ Q+L+ A + +K V + EK++ Q Sbjct: 1894 LRRVEETLKLERDQLKESLQETKARDLEIQQELKTARMLSKEHKETVDKLREKISEKTIQ 1953 Query: 329 LNKLTQNVSKSA-EMEKKVQDLEQK-LQLAYSKSD 427 ++ + +++ KS E++KK+Q+L++K LQL K D Sbjct: 1954 ISDIQKDLDKSKDELQKKIQELQKKELQLLRVKED 1988 Score = 32.0 bits (71), Expect = 1.6 Identities = 34/127 (26%), Positives = 59/127 (46%) Frame = +2 Query: 17 SKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLE 196 S MQ+ +L H D L+ Q L++++EL A+ + Q+E K + D+L Sbjct: 1752 SNMQK--DLEHSNDALKAQDLKIQEELRIAHMHLKEQQETID----KLRGIVSEKTDKLS 1805 Query: 197 VAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEMEK 376 QK +LE + L +++QE + + QL L ++V+ E +K Sbjct: 1806 NMQK---DLENSNAKLQEKIQELKAN---------------EHQLITLKKDVN---ETQK 1844 Query: 377 KVQDLEQ 397 KV ++EQ Sbjct: 1845 KVSEMEQ 1851 Score = 30.0 bits (66), Expect = 6.1 Identities = 38/200 (19%), Positives = 89/200 (44%), Gaps = 27/200 (13%) Frame = +2 Query: 2 NEALTSKMQEHANLVHEK-DQLE--------QQLLEVRKELEAAYRTIANQEEQASV--- 145 N+ L +++ L+ EK DQ++ Q+L ++ +L + +I + ++ Sbjct: 570 NQDLENELSSKVELLREKEDQIKKLQEYIDSQKLENIKMDLSYSLESIEDPKQMKQTLFD 629 Query: 146 -REIKWDAYKTYS---ADQLEVAQKHAAELEVQVSAL--DQQLQEAEIHYKNKVAEESEK 307 + DA + + ++ LE+ +K EL + D QL ++++ K K+ + EK Sbjct: 630 AETVALDAKRESAFLRSENLELKEK-MKELATTYKQMENDIQLYQSQLEAKKKMQVDLEK 688 Query: 308 -LALVNTQLNKLTQNVSKSA--------EMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTR 460 L ++ KLT + E+E K+ DL+++L +++ ++ ++ + Sbjct: 689 ELQSAFNEITKLTSLIDGKVPKDLLCNLELEGKITDLQKELNKEVEENEALREEVILLSE 748 Query: 461 SREFSLDSLTPQNKEQDLSQ 520 + + + + QD S+ Sbjct: 749 LKSLPSEVERLRKEIQDKSE 768
>RRBP1_HUMAN (Q9P2E9) Ribosome-binding protein 1 (Ribosome receptor protein) (180| kDa ribosome receptor homolog) (ES/130-related protein) Length = 1410 Score = 38.9 bits (89), Expect = 0.013 Identities = 47/201 (23%), Positives = 85/201 (42%), Gaps = 16/201 (7%) Frame = +2 Query: 14 TSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQL 193 TS+++ N E +L Q+L +V KEL + E+Q E K Sbjct: 813 TSQVESKQNA--ELAKLRQELSKVSKELVEKSEAVRQDEQQRKALEAK------------ 858 Query: 194 EVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEME 373 AA E QV L +E+E + ++ E S +L + L + K+ E + Sbjct: 859 ------AAAFEKQVLQLQASHRESEEALQKRLDEVSRELCHTQSSHASLRADAEKAQEQQ 912 Query: 374 KKVQDLEQKLQLA----YSKSDE-----------QAKDAVVSTRSREFSLDSLTPQNKEQ 508 +++ +L KLQ + SK +E +A+++ ++ R R S+++L + + Sbjct: 913 QQMAELHSKLQSSEAEVRSKCEELSGLHGQLQEARAENSQLTERIR--SIEALLEAGQAR 970 Query: 509 DLSQA-PSTASVNPAQQQLRE 568 D S A + Q +L+E Sbjct: 971 DAQDVQASQAEADQQQTRLKE 991
>REST_CHICK (O42184) Restin (Cytoplasmic linker protein 170) (CLIP-170)| Length = 1433 Score = 38.9 bits (89), Expect = 0.013 Identities = 51/213 (23%), Positives = 86/213 (40%), Gaps = 51/213 (23%) Frame = +2 Query: 35 ANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKH- 211 +NL E EQ+LL++ K L A + + E++ + + K+ T + D E AQ+ Sbjct: 803 SNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKF----TSAVDGAENAQRAM 858 Query: 212 -----------------AAELEVQVSAL-------------DQQLQEAEIHYKNKVAE-- 295 ++ELE S L +QQL EA++ +N +AE Sbjct: 859 QETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIM 918 Query: 296 -----ESEKLALVNTQLN-----------KLTQNVSKSAEMEKKVQDLEQKLQLAYSKSD 427 S +L +N +L +LT+ K+ +++K V+ QK Sbjct: 919 KSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKA-------- 970 Query: 428 EQAKDAVVSTRSREFS--LDSLTPQNKEQDLSQ 520 EQ++ + T E D LT K+ + SQ Sbjct: 971 EQSQQETLKTHQEELKKMQDQLTDMKKQMETSQ 1003 Score = 38.1 bits (87), Expect = 0.022 Identities = 47/181 (25%), Positives = 76/181 (41%), Gaps = 25/181 (13%) Frame = +2 Query: 50 EKDQLEQQLLEVRKELEAA---YRTI-ANQEEQASVREIKWDA----YKTYSADQ---LE 196 E +++ QL +++K++E + Y+ + A E++ S K DA +K D L+ Sbjct: 984 ELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMITKHDADIKGFKQNLLDAEEALK 1043 Query: 197 VAQKHAAELEVQVSALDQQ-------------LQEAEIHYKNKVAEESEKLALVNTQLNK 337 AQK ELE Q L +Q LQ E K K A EK+ + + N Sbjct: 1044 AAQKKNDELETQAEELKKQAEQAKADKRAEEVLQTMEKVTKEKDAIHQEKIETLASLENS 1103 Query: 338 LTQNVSKSAEMEK-KVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDL 514 N E++ K +L+ + +L SK ++ V +EF L K Q L Sbjct: 1104 RQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVEELKKEFEALKLAAAQKSQQL 1163 Query: 515 S 517 + Sbjct: 1164 A 1164
>CEP2_MOUSE (Q60952) Centrosomal protein 2 (Intranuclear matrix protein)| (Fragment) Length = 609 Score = 38.9 bits (89), Expect = 0.013 Identities = 40/151 (26%), Positives = 74/151 (49%), Gaps = 6/151 (3%) Frame = +2 Query: 23 MQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQ-ASVREIKWDAYKTYSADQLEV 199 +QE +L E+ + ++LLE KEL+ T+A +EE+ +RE +++ A++ + Sbjct: 255 IQEKQSLEQERQEETRRLLESLKELQL---TVAQREEEILMLREASSPSHRALPAEKPAL 311 Query: 200 AQKHA-AELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNV----SKSA 364 A ELE +AL +Q + EI ++ K + + LA ++ L + + Sbjct: 312 QPLPAQQELERLQTAL-RQTEAREIEWREKAQDLALSLAQSKASISSLQEITMFLQASVL 370 Query: 365 EMEKKVQDLEQKLQLAYSKSDEQAKDAVVST 457 E E + Q L+++L L+ +EQ ST Sbjct: 371 ERESEQQRLQEELVLSSQALEEQQSGGPHST 401
>YKF4_YEAST (P35732) Hypothetical 84.0 kDa protein in NUP120-CSE4 intergenic| region Length = 738 Score = 38.5 bits (88), Expect = 0.017 Identities = 37/165 (22%), Positives = 70/165 (42%) Frame = +2 Query: 77 LEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKHAAELEVQVSALDQQL 256 LE EL+ I ++++ E K + +T + +Q E + + E E +V +D + Sbjct: 262 LENVAELKKEISDIKKDDQKSEASEEKVNEQETSAQEQEEETAEPSEENEDRVPEVDGEE 321 Query: 257 QEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEMEKKVQDLEQKLQLAYSKSDEQA 436 + E K +V EE + +L Q A E++V +E+K++++ S+ Sbjct: 322 VQEEAEKKEQVKEEEQTA-------EELEQEQDNVAAPEEEVTVVEEKVEISAVISEPPE 374 Query: 437 KDAVVSTRSREFSLDSLTPQNKEQDLSQAPSTASVNPAQQQLREP 571 A + ++ S PQ +Q Q P QQ ++P Sbjct: 375 DQANTVPQPQQQSQQPQQPQQPQQ--PQQPQQPQQQQQPQQPQQP 417 Score = 35.4 bits (80), Expect = 0.14 Identities = 43/214 (20%), Positives = 95/214 (44%), Gaps = 24/214 (11%) Frame = +2 Query: 2 NEALTSKMQEHANLVHEKDQLEQQL------LEVRKELE---AAYRTIANQEEQASVREI 154 NE L ++ Q+ EK+Q EQQ E K++E + + ++ + +++ Sbjct: 183 NEELEAQGQQAQEKNQEKEQEEQQQQEGHNNKEEHKQIEQPSLSSKKTTSRTSASQPKKM 242 Query: 155 KWDAY---KTYSADQLEVAQKHAAELEVQVSAL--DQQLQEA---EIHYKNKVAEESEKL 310 W A K + + E ++ AEL+ ++S + D Q EA +++ + A+E E+ Sbjct: 243 SWAAIATPKPKAVKKTESPLENVAELKKEISDIKKDDQKSEASEEKVNEQETSAQEQEEE 302 Query: 311 ALVNTQLNKLT------QNVSKSAEMEKKVQDLEQKL-QLAYSKSDEQAKDAVVSTRSRE 469 ++ N+ + V + AE +++V++ EQ +L + + A + V+ + Sbjct: 303 TAEPSEENEDRVPEVDGEEVQEEAEKKEQVKEEEQTAEELEQEQDNVAAPEEEVTVVEEK 362 Query: 470 FSLDSLTPQNKEQDLSQAPSTASVNPAQQQLREP 571 + ++ + E + P + QQ ++P Sbjct: 363 VEISAVISEPPEDQANTVPQPQQQSQQPQQPQQP 396
>LIPA2_MOUSE (Q8BSS9) Liprin-alpha-2 (Protein tyrosine phosphatase receptor type| f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2) Length = 1257 Score = 38.5 bits (88), Expect = 0.017 Identities = 38/143 (26%), Positives = 62/143 (43%), Gaps = 6/143 (4%) Frame = +2 Query: 8 ALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSAD 187 ALT + H N+ LE QL E +EL+ A + EE D T S + Sbjct: 419 ALTKAEERHGNIEERMRHLEGQLEEKNQELQRARQREKMNEEHNKRLSDTVDRLLTESNE 478 Query: 188 QLEV-AQKHAAELE-----VQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQN 349 +L++ ++ A LE +Q S ++ E +H K +AEE EKL ++L+++ Sbjct: 479 RLQLHLKERMAALEEKNVLIQESENFRKNLEESLHDKVSLAEEIEKL---RSELDQMKMR 535 Query: 350 VSKSAEMEKKVQDLEQKLQLAYS 418 E ++ +L YS Sbjct: 536 TGSLIEPTISRTHIDTSTELRYS 558
>TPM_HELAS (O97192) Tropomyosin (Allergen Hel as 1)| Length = 284 Score = 38.5 bits (88), Expect = 0.017 Identities = 51/216 (23%), Positives = 104/216 (48%), Gaps = 30/216 (13%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEE-----QASVREIKWDAY 169 E L + ++ A L ++ D + +QLL+ +LEA+ + A E Q ++ ++ D Sbjct: 41 EDLNNLQKKFAILENDFDSINEQLLDANTKLEASEKKNAEIESETAGLQRRIQLLEEDLE 100 Query: 170 KT-----YSADQLEVAQKHAAE-------LEVQVSALDQQLQ--EAEIHYKNKVAEESE- 304 ++ + ++LE A K A E LE + A D++L EA++ +AE++E Sbjct: 101 RSEERLQSATEKLEEASKAADESERGRKVLESRSLADDERLDGLEAQLKEAKYIAEDAER 160 Query: 305 -------KLALVNTQLNKLTQNVSKSAEMEKKVQDLEQKLQLAYS--KSDE-QAKDAVVS 454 KLA+ L + + + E K+ +LE++L++ + KS E ++A Sbjct: 161 KFDEAARKLAITEVDLERAEARLEAA---EAKILELEEELKVVGNNMKSLEISEQEASQR 217 Query: 455 TRSREFSLDSLTPQNKEQDLSQAPSTASVNPAQQQL 562 S E ++ LT + K+ + + + +V+ Q+++ Sbjct: 218 EDSYEETIRDLTQRLKDAENRASEAERTVSKLQKEV 253
>MYSP_BOOMI (Q86RN8) Paramyosin| Length = 873 Score = 38.5 bits (88), Expect = 0.017 Identities = 46/200 (23%), Positives = 88/200 (44%), Gaps = 16/200 (8%) Frame = +2 Query: 17 SKMQEHANLVHEKDQLEQQLLEVRKELEAAYR---TIANQEEQ---------ASVREIKW 160 S++ + +HE + ++L R EL AAY+ T+ QEE A VR ++ Sbjct: 436 SQLADAIRRLHEYELEIKRLENERDELAAAYKEAETLRKQEEAKCQRLTAELAQVRH-EY 494 Query: 161 DAYKTYSADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKL 340 + +++E +K + +++V L+ +L EAE K ++A +K T+L Sbjct: 495 ERRLQIKEEEIEALRK---QYQLEVEQLNMRLAEAEAKLKTEIARIKKKYQAQITELEMS 551 Query: 341 TQNVSK-SAEMEK--KVQDLE-QKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQ 508 +K + +++K K Q ++ +LQ Y + Q + + L + EQ Sbjct: 552 LDAANKQNMDLQKIIKKQAIQITELQAHYDEVHRQLQQCADQLAISQRRCQGLQAELDEQ 611 Query: 509 DLSQAPSTASVNPAQQQLRE 568 ++ + S A+Q L E Sbjct: 612 RVALESALRSKRAAEQSLEE 631
>MYH11_RABIT (P35748) Myosin-11 (Myosin heavy chain, smooth muscle isoform)| (SMMHC) Length = 1972 Score = 38.5 bits (88), Expect = 0.017 Identities = 49/202 (24%), Positives = 80/202 (39%), Gaps = 14/202 (6%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYK---- 172 E L S+ +K L ++L ++ ELE T A Q+E + RE + K Sbjct: 1125 EDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDTTATQQELRAKREQEVTVLKKALD 1184 Query: 173 ----TYSADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKL 340 ++ A E+ QKH +E L+Q + K K E E L +L L Sbjct: 1185 EETRSHEAQVQEMRQKHTQVVEELTEQLEQFKRAKANLDKTKQTLEKENADLAG-ELRVL 1243 Query: 341 TQNVSKSAEMEKKVQDLEQKLQLAYSKSDE------QAKDAVVSTRSREFSLDSLTPQNK 502 Q E+E K + LE +LQ SK + + D V ++ S+ + + + Sbjct: 1244 GQ---AKQEVEHKKKKLEVQLQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLSEAE 1300 Query: 503 EQDLSQAPSTASVNPAQQQLRE 568 + + A AS+ Q +E Sbjct: 1301 GKAIKLAKEVASLGSQLQDTQE 1322 Score = 36.6 bits (83), Expect = 0.065 Identities = 37/175 (21%), Positives = 79/175 (45%), Gaps = 9/175 (5%) Frame = +2 Query: 17 SKMQEHANLVHEK-DQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQL 193 +K+ + L+ E+ L L E ++ + + E S E++ + S +L Sbjct: 995 NKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEK-SRQEL 1053 Query: 194 EVAQK----HAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKS 361 E ++ A++L Q++ L Q+ E ++ K E LA + + ++ + K Sbjct: 1054 EKLKRKMDGEASDLHEQIADLQAQIAELKMQLAKKEEELQAALARLEDETSQKNNALKKI 1113 Query: 362 AEMEKKVQDLEQKL---QLAYSKSDEQAKDAVVSTRSREFSL-DSLTPQNKEQDL 514 E+E + DL++ L + A +K+++Q +D + + L D+L +Q+L Sbjct: 1114 RELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDTTATQQEL 1168 Score = 36.6 bits (83), Expect = 0.065 Identities = 50/227 (22%), Positives = 84/227 (37%), Gaps = 38/227 (16%) Frame = +2 Query: 11 LTSKMQEHANLVHEKDQL-------EQQLLEVRKELEAAYRTIANQEEQASVREIKWDAY 169 L ++Q L E +++ +Q+L E+ E+EA ++ +Q K Sbjct: 892 LQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQ 951 Query: 170 KTYSADQLE--------------VAQKHAAELEVQVSALDQQ----------LQEAEIHY 277 +QLE A+ +LE + +D Q L+E Sbjct: 952 MLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDDILVMDDQNNKLSKERKLLEERISDL 1011 Query: 278 KNKVAEESEKLALVNTQLNKLTQNVSKSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVST 457 +AEE EK + NK +S+ KK + Q+L+ K D +A D Sbjct: 1012 TTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKMDGEASDLHEQI 1071 Query: 458 RSREFSLDSLTPQ--NKEQDLSQA-----PSTASVNPAQQQLREPSG 577 + + L Q KE++L A T+ N A +++RE G Sbjct: 1072 ADLQAQIAELKMQLAKKEEELQAALARLEDETSQKNNALKKIRELEG 1118
>SPH_STRP1 (P50470) Immunoglobulin G-binding protein H precursor (IgG-binding| protein H) Length = 376 Score = 38.5 bits (88), Expect = 0.017 Identities = 48/201 (23%), Positives = 91/201 (45%), Gaps = 12/201 (5%) Frame = +2 Query: 20 KMQEHANLVHEKDQLEQQLLEVRKE-LEAAYR---------TIANQEEQASVREIKWDAY 169 K +H + H+K+Q EQ+ + +E LE Y+ + Q++ + ++I + Sbjct: 107 KKLDHEHKEHQKEQQEQEERQKNQEQLERKYQREVEKRYQEQLQKQQQLETEKQISEASR 166 Query: 170 KTYSADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQN 349 K+ S D LE ++ +LE + Q EAE H K K E + + L+++ Sbjct: 167 KSLSRD-LEASRAAKKDLEA-----EHQKLEAE-HQKLK-----EDKQISDASRQGLSRD 214 Query: 350 VSKSAEMEKKVQDLEQKLQLAYS--KSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQA 523 + S +K+++ QKL+ + K D+Q DA SR+ L++ KE + + Sbjct: 215 LEASRAAKKELEANHQKLEAEHQKLKEDKQISDASRQGLSRD--LEASRAAKKELEANHQ 272 Query: 524 PSTASVNPAQQQLREPSGIMA 586 A ++QL + + +A Sbjct: 273 KLEAEAKALKEQLAKQAEELA 293
>RAD50_MOUSE (P70388) DNA repair protein RAD50 (EC 3.6.-.-) (mRad50)| Length = 1312 Score = 38.5 bits (88), Expect = 0.017 Identities = 33/129 (25%), Positives = 60/129 (46%), Gaps = 12/129 (9%) Frame = +2 Query: 92 ELEAAYRTIANQEEQASVREIKWDAYKTYSAD--QLEVAQKHAAELEVQVSALDQQL--- 256 E+ +A R I + VR+ + K + L+ ++ A E+ Q+++ + QL Sbjct: 178 EIFSATRYIKALDTLRQVRQTQGQKVKECQTELKYLKQNKEKACEIRDQITSKEAQLASS 237 Query: 257 QEAEIHY-------KNKVAEESEKLALVNTQLNKLTQNVSKSAEMEKKVQDLEQKLQLAY 415 QE Y KN++ E L+ + N++ S+ +MEK +LEQK++ + Sbjct: 238 QEIVRSYEDELEPLKNRLKEIEHNLSKIMKLDNEIKALESRKKQMEKDNSELEQKMEKVF 297 Query: 416 SKSDEQAKD 442 +DEQ D Sbjct: 298 QGTDEQLND 306
>CENPF_HUMAN (P49454) CENP-F kinetochore protein (Centromere protein F) (Mitosin)| (AH antigen) Length = 3210 Score = 38.5 bits (88), Expect = 0.017 Identities = 44/215 (20%), Positives = 87/215 (40%), Gaps = 21/215 (9%) Frame = +2 Query: 11 LTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAY------- 169 L K QE + + + L KEL + N +E +E + Sbjct: 2518 LQEKEQEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEACKAKEQNLSSQVECLELE 2577 Query: 170 KTYSADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQN 349 K L+ A+ + L+ V+ L Q++++ K K+ ++ E+++ + Q+ Q Sbjct: 2578 KAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDG----KQKLEKKDEEISRLKNQIQDQEQL 2633 Query: 350 VSKSAEMEKKVQ--------------DLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSL 487 VSK +++E + Q +LEQK+Q+ SK + +D + +S +L++ Sbjct: 2634 VSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQSK-NASLQDTLEVLQSSYKNLENE 2692 Query: 488 TPQNKEQDLSQAPSTASVNPAQQQLREPSGIMAFK 592 K +S + + +L+ MA K Sbjct: 2693 LELTKMDKMSFVEKVNKMTAKETELQREMHEMAQK 2727 Score = 37.7 bits (86), Expect = 0.029 Identities = 32/127 (25%), Positives = 61/127 (48%), Gaps = 1/127 (0%) Frame = +2 Query: 26 QEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQE-EQASVREIKWDAYKTYSADQLEVA 202 QEHA L E + E + L+ + +E +++ E + ++R K D ++L+ Sbjct: 2448 QEHAALEAENSKGEVETLKAK--IEGMTQSLRGLELDVVTIRSEKEDL-----TNELQKE 2500 Query: 203 QKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEMEKKV 382 Q+ +ELE+ S+ + LQE E + S + ++ TQL +L + V+ ++ Sbjct: 2501 QERISELEIINSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEAC 2560 Query: 383 QDLEQKL 403 + EQ L Sbjct: 2561 KAKEQNL 2567 Score = 33.1 bits (74), Expect = 0.72 Identities = 36/149 (24%), Positives = 63/149 (42%), Gaps = 15/149 (10%) Frame = +2 Query: 8 ALTSKMQEHANLVHEK-------DQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDA 166 AL K +E+ L EK + E+ L ++ E E I + E ++IK Sbjct: 601 ALELKKKEYEELKEEKTLFSCWKSENEKLLTQMESEKENLQSKINHLETCLKTQQIKSHE 660 Query: 167 Y----KTYSADQ----LEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVN 322 Y +T D+ +E+ H V Q+L E+ K + +++ + + N Sbjct: 661 YNERVRTLEMDRENLSVEIRNLHNVLDSKSVEVETQKLAYMELQQKAEFSDQKHQKEIEN 720 Query: 323 TQLNKLTQNVSKSAEMEKKVQDLEQKLQL 409 L K++++ +V+DLE KLQL Sbjct: 721 MCL--------KTSQLTGQVEDLEHKLQL 741 Score = 32.3 bits (72), Expect = 1.2 Identities = 31/133 (23%), Positives = 57/133 (42%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSA 184 E + + L E ++ Q+ E+++EL +A E Q + EIK S Sbjct: 2705 EKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAG-ELQLLLEEIK------SSK 2757 Query: 185 DQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSA 364 DQL+ +EL+ + + + E E + ++AE +L + L + +K Sbjct: 2758 DQLKELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKHQALLLDTNKQY 2817 Query: 365 EMEKKVQDLEQKL 403 E+E +Q +KL Sbjct: 2818 EVE--IQTYREKL 2828
>PLCB1_HUMAN (Q9NQ66) 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase| beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C-beta-1) (PLC-beta-1) (PLC-I) (PLC-154) Length = 1216 Score = 38.5 bits (88), Expect = 0.017 Identities = 36/152 (23%), Positives = 76/152 (50%), Gaps = 8/152 (5%) Frame = +2 Query: 8 ALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSAD 187 AL ++M + L+ KD+ +QQLL +R+E + + + + ++++ D + + Sbjct: 996 ALDAEMTQ--KLIDLKDKQQQQLLNLRQEQYYSEKYQKREHIKLLIQKLT-DVAEECQNN 1052 Query: 188 QL----EVAQKHAAELEVQVSALDQQLQE--AEIHYKNKVAEESEKLALVNTQLNKLTQN 349 QL E+ +K EL+ +D++ QE E K+K E EK ++ + + ++ Q Sbjct: 1053 QLKKLKEICEKEKKELK---KKMDKKRQEKITEAKSKDKSQMEEEKTEMIRSYIQEVVQY 1109 Query: 350 VSKSAEMEKKVQD--LEQKLQLAYSKSDEQAK 439 + + E + K Q+ +E+ ++ DE+ K Sbjct: 1110 IKRLEEAQSKRQEKLVEKHKEIRQQILDEKPK 1141
>MYSP_CAEEL (P10567) Paramyosin| Length = 882 Score = 38.5 bits (88), Expect = 0.017 Identities = 42/206 (20%), Positives = 97/206 (47%), Gaps = 14/206 (6%) Frame = +2 Query: 2 NEALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYS 181 N ++ + + NL K++LE +L + +L+ + + +E+A+ + A + Sbjct: 654 NGRISDLISINNNLTSIKNKLETELSTAQADLDEVTKELHAADERAN----RALADAARA 709 Query: 182 ADQLEVAQKHAAE-------LEVQVSALDQQLQEAE----IHYKNKVAEESEKLALVNTQ 328 +QL Q+H+ + LE QV L Q+QEAE + K +A+ ++ + T Sbjct: 710 VEQLHEEQEHSMKIDALRKSLEEQVKQLQVQIQEAEAAALLGGKRVIAKLETRIRDLETA 769 Query: 329 LNKLTQNVSKSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQ 508 L++ T+ + E + ++ +++++ DE+ K+ V++ + + + L Q ++ Sbjct: 770 LDEETR---RHKETQNALRKKDRRIKEVQQLVDEEHKNFVMAQDTADRLTEKLNIQKRQL 826 Query: 509 DLSQAPSTAS---VNPAQQQLREPSG 577 S++ + + V Q +L + G Sbjct: 827 AESESVTMQNLQRVRRYQHELEDAEG 852
>SMC4_MICAR (Q9ERA5) Structural maintenance of chromosomes 4-like 1 protein| (Chromosome-associated polypeptide C) (XCAP-C homolog) (Fragment) Length = 1243 Score = 38.5 bits (88), Expect = 0.017 Identities = 35/185 (18%), Positives = 80/185 (43%), Gaps = 21/185 (11%) Frame = +2 Query: 11 LTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQ 190 + + +++ A + E+ L KELEA T A +++ + E A+K + Sbjct: 769 MRNTLEKFAASIQGLSDQEEYLTVQIKELEANVLTTAPDKKKQKLLEENVSAFK----KE 824 Query: 191 LEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKS--- 361 + + A ++E +V L + E K+ + KL ++N QL++ ++K+ Sbjct: 825 YDAVAEKAGKVEAEVKRLHDTIIEIN---NRKLKAQQNKLDMINKQLDECASAITKAQVA 881 Query: 362 ---------------AEMEKKVQDLEQK---LQLAYSKSDEQAKDAVVSTRSREFSLDSL 487 EK+++D E++ L+ +++A++ + T + E SL + Sbjct: 882 IKTADRNLIKAQDSVVRTEKEIKDTEKETNDLKAELKAIEDKAEEVIKKTNAAEESLPEI 941 Query: 488 TPQNK 502 +++ Sbjct: 942 QKEHR 946
>RAD50_DROME (Q9W252) DNA repair protein RAD50 (EC 3.6.-.-)| Length = 1318 Score = 38.5 bits (88), Expect = 0.017 Identities = 46/216 (21%), Positives = 91/216 (42%), Gaps = 34/216 (15%) Frame = +2 Query: 38 NLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSA----------- 184 +L EK ++ ++L RKELE+A + Q + + K ++ K Sbjct: 834 DLQAEKSKVSKELETERKELESAQNAVQQQMDALNRLREKKNSLKDRQIHLREGLQSLPQ 893 Query: 185 --DQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAE-------ESEKLALVNTQLNK 337 ++LE + ++S L ++Q +++ + + E ESEKLA +N++ N Sbjct: 894 LKERLEKLNSFLTTVASEISELKAKIQPLKLNLRAAIEEKERLKKSESEKLAQLNSKYNS 953 Query: 338 L------TQNVSKSAEMEKKVQDLEQKLQ-----LAYSKSDEQAKDAVVSTRSRE---FS 475 Q ++K AE K+ DL +++ + SK + +A +S ++ E Sbjct: 954 YKSTDHDIQRLNKEAEDYAKL-DLRNEIKKLDEIIMASKDKLRKLEAEISLKTDELETIK 1012 Query: 476 LDSLTPQNKEQDLSQAPSTASVNPAQQQLREPSGIM 583 + Q E+DL + + +LRE ++ Sbjct: 1013 TECSNQQTVERDLKDNRELKQLEDKEAKLRESCQVL 1048 Score = 30.8 bits (68), Expect = 3.6 Identities = 33/157 (21%), Positives = 75/157 (47%), Gaps = 6/157 (3%) Frame = +2 Query: 11 LTSKMQEHANLVH---EKDQLEQ--QLLEVRKELEAAYRTIANQEEQASVREIKWDAYKT 175 L +++E +H + D +EQ ++ EV +++EA T + + + K D + Sbjct: 374 LLKRVKEFCRELHIPIDCDLVEQPEKMGEVLRDIEAMIITKHCEITEIVEQNEKADRSRQ 433 Query: 176 YSADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVS 355 D+L + + E V+A ++Q + ++ ESE L + ++ K+ ++ Sbjct: 434 VKIDELRI---ELTKSEQSVTAQEKQRESSK--------RESETLGV---EIKKIETSMQ 479 Query: 356 KSAEMEKKVQDLEQKLQLAYSKSDEQA-KDAVVSTRS 463 ++EK++ ++ + + A D+QA KDA+ ++ Sbjct: 480 DLKKLEKEINEVNELYESATKNIDQQAIKDAIARKKA 516
>YBE7_YEAST (P34216) Protein YBL047C| Length = 1381 Score = 38.5 bits (88), Expect = 0.017 Identities = 30/134 (22%), Positives = 63/134 (47%), Gaps = 14/134 (10%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSA 184 + L K+ + E + ++ + E +L+A Y+ ++N++ + RE + + Sbjct: 768 DGLGEKISVYLTKQKELNDYQKTVEEQHAQLQAKYQDLSNKDTDLTDREKQLEERNRQIE 827 Query: 185 DQLEVAQKHAAELEVQVSAL----------DQQLQEAEIHYKNKVAEESEKLALVNTQLN 334 +Q + +H ++L+ L DQ+L+E I Y N V E SE+ +N + Sbjct: 828 EQENLYHQHVSKLQEMFDDLSQRKASFEKADQELKERNIEYANNVRELSER--QMNLAMG 885 Query: 335 KLTQN----VSKSA 364 +L ++ ++KSA Sbjct: 886 QLPEDAKDIIAKSA 899
>GOGA4_MOUSE (Q91VW5) Golgin subfamily A member 4 (tGolgin-1)| Length = 2238 Score = 38.5 bits (88), Expect = 0.017 Identities = 48/196 (24%), Positives = 88/196 (44%), Gaps = 25/196 (12%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQ-----------LEQQLLEVRKELEAAYRTIANQEEQASVRE 151 +AL ++ L+ E+D+ LE L + EL+ A + + S Sbjct: 772 KALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAR 831 Query: 152 IKWDAYKTYSADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQL 331 + AY+ +QL Q+ +LE + S L +Q+ E E H K V EE ++ Q Sbjct: 832 EQAGAYE----EQLAQMQQKVLDLETEKSLLTKQVVEMETH-KKHVCEE------LDAQR 880 Query: 332 NKLTQNVSKSAEMEKKVQDLEQKLQLAYSKSD----EQAKDAVV----------STRSRE 469 ++ Q + +E+E+KV+ L Q LQ + K+ EQA+ +++ +++E Sbjct: 881 AQVQQLERQRSELEEKVRSLAQ-LQDSQLKNSTVEKEQARQSLMEKENIILQMREEQAKE 939 Query: 470 FSLDSLTPQNKEQDLS 517 + T +KE+ +S Sbjct: 940 IEILKQTLSSKEESIS 955 Score = 37.7 bits (86), Expect = 0.029 Identities = 55/220 (25%), Positives = 100/220 (45%), Gaps = 33/220 (15%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQQL------LEVRKELEAAYRT-----------IANQEE 133 E + S ++ A L+ EK+ L++QL LE KEL A +T + Q E Sbjct: 320 ETIGSHKEQCALLLSEKEALQEQLDERLQELEKMKELHMAEKTKLITQLRDAKNLIEQLE 379 Query: 134 QAS---VREIKWDAYKTYSADQLEVAQ--KHAAELEVQVSALDQQLQEAEIHYKNKVAEE 298 Q + E K +T + E+AQ H ++ Q L +Q +++E + A E Sbjct: 380 QDKGMVITETKRQMLETLELKEDEIAQLRSHIKQMTTQGEELREQKEKSE-----RAAFE 434 Query: 299 SEKLALVNTQLNKLTQNVSKSAEMEKKVQDL-----EQKLQLAYSKSDEQAKDAVVSTRS 463 + AL Q + Q K EM+++++ + E++L+L + S + + A ++ ++ Sbjct: 435 ELEKALSTAQKTEDAQRRMK-MEMDEQMKAVERASEEERLRLQHELSRVRQEAASMAKKN 493 Query: 464 REFSLDSLTP------QNKEQDLSQAPSTASVNPAQQQLR 565 E + +L +KEQ+LS+ A Q+Q+R Sbjct: 494 SEEQVAALQKLHAEELASKEQELSRR-LEARERELQEQMR 532 Score = 35.0 bits (79), Expect = 0.19 Identities = 40/173 (23%), Positives = 83/173 (47%), Gaps = 4/173 (2%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSA 184 EA+++ ++H ++ QL+ QL E+ +++A + + EQ K+ +K + Sbjct: 1409 EAISALSKQHEE---QELQLQAQLQELSLKVDALSKEKMSALEQVDHWSNKFSEWKKKAQ 1465 Query: 185 DQLEVAQKHAAELEVQ--VSALDQQLQEAEIHY-KNKVAEESEKLALVNTQLNKLTQNVS 355 +L Q +L+ Q V A D + +E +I K + +++K + ++ Sbjct: 1466 SRLAQHQSTIKDLQAQLDVKATDAREKEEQICLLKEDLDRQNKKFECLKGEMEV------ 1519 Query: 356 KSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSL-DSLTPQNKEQD 511 + ++MEKK DLE L+ ++ E +D V + SL ++L N+++D Sbjct: 1520 RKSKMEKKECDLETALKTQTARVVE-LEDCVTQRKKEVESLNETLKNYNQQRD 1571 Score = 31.6 bits (70), Expect = 2.1 Identities = 23/83 (27%), Positives = 40/83 (48%) Frame = +2 Query: 20 KMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEV 199 K EH N + E + LE + ELE+A + ++ + + I+ K + E Sbjct: 1621 KELEHVNSSVKSRDGELKALEDKLELESAAKVELKRKAEQKIAAIR----KQLLSQMEEK 1676 Query: 200 AQKHAAELEVQVSALDQQLQEAE 268 Q++A + E ++S L QL+E E Sbjct: 1677 TQRYAKDTENRLSELSAQLKERE 1699
>SMC1A_RAT (Q9Z1M9) Structural maintenance of chromosome 1-like 1 protein| (SMC-protein) Length = 1233 Score = 38.5 bits (88), Expect = 0.017 Identities = 36/170 (21%), Positives = 77/170 (45%), Gaps = 3/170 (1%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSA 184 ++L ++ + + + D+LE+++L V K + + +E Q+ R++ + + Sbjct: 317 KSLQNRQKHYKKRKGDMDELEKEMLSVEKARQE-FEERMEEESQSQGRDLTLEENQVKKY 375 Query: 185 DQL-EVAQKHAAEL--EVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVS 355 +L E A K AA L E++ DQ+ + + + + E+E K+ Q + Sbjct: 376 HRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEERKKVETEA---------KIKQKLR 426 Query: 356 KSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKE 505 + E +K+++ LE+ + + +EQ K T E + + NKE Sbjct: 427 EIEENQKRIEKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRRIDEINKE 476
>MYO5C_HUMAN (Q9NQX4) Myosin-5C (Myosin Vc)| Length = 1742 Score = 38.5 bits (88), Expect = 0.017 Identities = 45/184 (24%), Positives = 79/184 (42%), Gaps = 17/184 (9%) Frame = +2 Query: 68 QQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKHAAELEVQVSALD 247 +++ ++ ELE A N EE K Y+ ++L QKH +ELE Q + Sbjct: 924 EKIQKLEAELEKAATHRRNYEE-------KGKRYRDAVEEKLAKLQKHNSELETQKEQIQ 976 Query: 248 QQLQEAEIHYKNK-----------VAEESEKLALVNTQLNKLTQNVSKSAE-MEKKVQDL 391 +LQE K K V +E + L+ TQ+ K + ++++++ L Sbjct: 977 LKLQEKTEELKEKMDNLTKQLFDDVQKEERQRMLLEKSFELKTQDYEKQIQSLKEEIKAL 1036 Query: 392 -EQKLQLAYSKSDEQAKD----AVVSTRSREFSLDSLTPQNKEQDLSQAPSTASVNPAQQ 556 ++K+QL + E A V+ S++ + +++ KE +L QA Q Sbjct: 1037 KDEKMQLQHLVEGEHVTSDGLKAEVARLSKQ--VKTISEFEKEIELLQAQKIDVEKHVQS 1094 Query: 557 QLRE 568 Q RE Sbjct: 1095 QKRE 1098 Score = 35.0 bits (79), Expect = 0.19 Identities = 35/152 (23%), Positives = 69/152 (45%), Gaps = 3/152 (1%) Frame = +2 Query: 26 QEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQ 205 Q+ + L +K LE +L E ++++ ++NQ ++ E + Q E+ Sbjct: 1216 QQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHRSQEEE---GTQRKALEAQNEI-- 1270 Query: 206 KHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLT---QNVSKSAEMEK 376 H E E + + Q++QEA H K + ESE + ++LT +++ + +M+ Sbjct: 1271 -HTKEKEKLIDKI-QEMQEASDHLKKQFETESEVKCNFRQEASRLTLENRDLEEELDMKD 1328 Query: 377 KVQDLEQKLQLAYSKSDEQAKDAVVSTRSREF 472 +V Q SK+ +A D S+ +E+ Sbjct: 1329 RVIKKLQDQVKTLSKTIGKANDVHSSSGPKEY 1360
>CLPB1_SYNEL (Q8DJ40) Chaperone clpB 1| Length = 871 Score = 38.5 bits (88), Expect = 0.017 Identities = 36/137 (26%), Positives = 68/137 (49%), Gaps = 9/137 (6%) Frame = +2 Query: 11 LTSKMQEHANLVHEKDQLEQQLLEVRKE--------LEAAYRTIANQEEQASVREIKWDA 166 +TSK +E + + QLE + L ++KE LE R +A+ +E+ S +W A Sbjct: 406 ITSKPEELDEIDRKILQLEMERLSLQKETSAASRDRLEKLERELADLKEEQSRLNAQWQA 465 Query: 167 YKTYSADQLEVAQKHAAELEVQVSALDQQLQEAEIHYK-NKVAEESEKLALVNTQLNKLT 343 K D+L+ ++ ++ ++ ++Q+AE +Y N+ AE + KLT Sbjct: 466 EKEV-IDRLQ-------SIKEEIEKVNIEIQQAERNYDLNRAAE---------LKYGKLT 508 Query: 344 QNVSKSAEMEKKVQDLE 394 + K AE E K+++++ Sbjct: 509 ELHKKLAEAEAKLREIQ 525
>CEP57_MOUSE (Q8CEE0) Centrosomal protein of 57 kDa (Cep57 protein)| (Testis-specific protein 57) (Translokin) Length = 500 Score = 38.5 bits (88), Expect = 0.017 Identities = 36/150 (24%), Positives = 64/150 (42%), Gaps = 17/150 (11%) Frame = +2 Query: 8 ALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSAD 187 AL + + L E+ Q E+ + + +E + + Q ++ + + + A Sbjct: 72 ALKNLQDKIRRLELERIQAEESVKTLSRETIEYKKVLDEQIQERENSKNEESKHNQELAS 131 Query: 188 QLEVAQKHAAELEVQVSALDQQLQEAEI-----------------HYKNKVAEESEKLAL 316 QL A+ LE Q+ + ++ AE+ H + V + EKL L Sbjct: 132 QLVAAENKCNLLEKQLEYMRNMIKHAEMERTSVLEKQVSLERERQHDQTHVQSQLEKLDL 191 Query: 317 VNTQLNKLTQNVSKSAEMEKKVQDLEQKLQ 406 + + NKLT + A EKK+Q+LE KL+ Sbjct: 192 LEQEYNKLT---AMQALAEKKMQELESKLR 218
>MYH7_PAPHA (P11778) Myosin heavy chain, cardiac muscle beta isoform| (MyHC-beta) (Fragment) Length = 244 Score = 38.1 bits (87), Expect = 0.022 Identities = 39/181 (21%), Positives = 83/181 (45%), Gaps = 35/181 (19%) Frame = +2 Query: 29 EHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQAS---------VREIKWDA----- 166 ++ +L+++K +++ L +++ E+E A + N EE+A E+K + Sbjct: 28 QNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAH 87 Query: 167 ----------------YKTYSADQLEV--AQKHAAELEVQVSALDQQLQEAEIHYKNKVA 292 ++ A+Q+ + +K +LE +V L+ +L EAE + + A Sbjct: 88 LERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENEL-EAE---QKRNA 143 Query: 293 EESEKLALVNTQLNKLTQNVSKSAEMEKKVQDLEQKLQL---AYSKSDEQAKDAVVSTRS 463 E + + ++ +LT + + ++QDL KLQL AY + E+A++ + S Sbjct: 144 ESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLS 203 Query: 464 R 466 + Sbjct: 204 K 204
>INVO_TARBA (P24711) Involucrin| Length = 387 Score = 38.1 bits (87), Expect = 0.022 Identities = 32/174 (18%), Positives = 74/174 (42%), Gaps = 9/174 (5%) Frame = +2 Query: 20 KMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEV 199 + + H +K Q ++ L ++E + + Q+++ +E+ + Q + Sbjct: 91 EQEVHPGKQQQKPQEQEAHLGKKQEPQGQEVHLGKQQQKTQEQEV-------HLGKQQQE 143 Query: 200 AQKHAAELEVQVSA-----LDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSA 364 Q+ LE Q+ L++QLQE E+H + ++ E +L L Q Q Sbjct: 144 LQEQEVHLEKQLQEPQEVHLEKQLQEQEVHLEKQLQEPEPELNLGKQQQEPQEQEAYLGK 203 Query: 365 EMEKKVQDLEQKLQLAYSKSDEQAKDAVV----STRSREFSLDSLTPQNKEQDL 514 + ++ + + +L L + + Q ++ + + +E L +++EQ+L Sbjct: 204 QQQELPEPQDPELHLGKQQQEPQEQEVQLEKQQEAQEQELHLGKQQQESQEQEL 257 Score = 31.2 bits (69), Expect = 2.7 Identities = 24/129 (18%), Positives = 57/129 (44%), Gaps = 4/129 (3%) Frame = +2 Query: 32 HANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKH 211 H ++ Q ++ LE ++E + + Q++++ +E+ +L+ + Sbjct: 217 HLGKQQQEPQEQEVQLEKQQEAQEQELHLGKQQQESQEQELH--------LRKLQQVPQE 268 Query: 212 AAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNV----SKSAEMEKK 379 + E+ + Q+LQE E+H ++ E E+ + Q +L + K ++ K Sbjct: 269 PQDQELHLGKQQQELQEQEVHLGKQLQEPQEQELHLGRQQQELQEEEVHLGMKEEQLLKH 328 Query: 380 VQDLEQKLQ 406 V+ E +L+ Sbjct: 329 VEQQEGQLE 337
>MYH7_RAT (P02564) Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta)| Length = 1935 Score = 38.1 bits (87), Expect = 0.022 Identities = 39/181 (21%), Positives = 83/181 (45%), Gaps = 35/181 (19%) Frame = +2 Query: 29 EHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQAS---------VREIKWDA----- 166 ++ +L+++K +++ L +++ E+E A + N EE+A E+K + Sbjct: 1719 QNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAH 1778 Query: 167 ----------------YKTYSADQLEV--AQKHAAELEVQVSALDQQLQEAEIHYKNKVA 292 ++ A+Q+ + +K +LE +V L+ +L EAE + + A Sbjct: 1779 LERMKNNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENEL-EAE---QKRNA 1834 Query: 293 EESEKLALVNTQLNKLTQNVSKSAEMEKKVQDLEQKLQL---AYSKSDEQAKDAVVSTRS 463 E + + ++ +LT + + ++QDL KLQL AY + E+A++ + S Sbjct: 1835 ESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLS 1894 Query: 464 R 466 + Sbjct: 1895 K 1895
>MYH7_HUMAN (P12883) Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta)| Length = 1935 Score = 38.1 bits (87), Expect = 0.022 Identities = 39/181 (21%), Positives = 83/181 (45%), Gaps = 35/181 (19%) Frame = +2 Query: 29 EHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQAS---------VREIKWDA----- 166 ++ +L+++K +++ L +++ E+E A + N EE+A E+K + Sbjct: 1719 QNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAH 1778 Query: 167 ----------------YKTYSADQLEV--AQKHAAELEVQVSALDQQLQEAEIHYKNKVA 292 ++ A+Q+ + +K +LE +V L+ +L EAE + + A Sbjct: 1779 LERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENEL-EAE---QKRNA 1834 Query: 293 EESEKLALVNTQLNKLTQNVSKSAEMEKKVQDLEQKLQL---AYSKSDEQAKDAVVSTRS 463 E + + ++ +LT + + ++QDL KLQL AY + E+A++ + S Sbjct: 1835 ESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLS 1894 Query: 464 R 466 + Sbjct: 1895 K 1895
>MYSC_CHICK (P29616) Myosin heavy chain, cardiac muscle isoform (Fragment)| Length = 1102 Score = 38.1 bits (87), Expect = 0.022 Identities = 44/217 (20%), Positives = 91/217 (41%), Gaps = 29/217 (13%) Frame = +2 Query: 29 EHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQAS---------VREIK-------- 157 ++ +L+++K +LE + +++ E+E + + N E++A E+K Sbjct: 885 QNTSLINQKKKLEGDISQMQNEVEESIQECRNAEQKAKKAITDAAMMAEELKKEQDTSAH 944 Query: 158 WDAYKTYSADQLEVAQKHAAELEV--------QVSALDQQLQEAEIHYKNKVAEESEK-- 307 + K ++ QK E E Q+ L+ +++E E +N++ S+ Sbjct: 945 LERMKKNMEQTIKDLQKRLDEAEQIALKGGKKQIQKLESRVRELENELENELRRNSDAQK 1004 Query: 308 -LALVNTQLNKLTQNVSKSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDS 484 ++ +LT + + ++QDL KLQL QA++A + +L Sbjct: 1005 GARKFERRIKELTYQSEEDKKNLARMQDLIDKLQLKVKSYKHQAEEA-----EAQANLYL 1059 Query: 485 LTPQNKEQDLSQAPSTASVNPAQ-QQLREPSGIMAFK 592 + ++ DL A A + +Q +LR S + K Sbjct: 1060 SKYRKQQHDLDDAEERAEIAESQVDKLRSKSRDIGMK 1096 Score = 36.6 bits (83), Expect = 0.065 Identities = 30/152 (19%), Positives = 70/152 (46%) Frame = +2 Query: 11 LTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQ 190 L ++Q + + + ++ L++ + +LEA + + + E + + K D+ Sbjct: 53 LLLQLQAEQDTLADAEERCDLLIKSKIQLEAKVKELTERVEDEEEMNSELTSKKRKLEDE 112 Query: 191 LEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEM 370 +K +LE+ ++ ++++ E NKV +E++A ++ ++KLT+ E Sbjct: 113 CSELKKDIDDLEITLAKVEKEKHATE----NKVKNLTEEMATLDENISKLTKEKKSLQEA 168 Query: 371 EKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSR 466 ++V D D QA++ V+T S+ Sbjct: 169 HQQVLD------------DLQAEEDKVNTLSK 188 Score = 33.9 bits (76), Expect = 0.42 Identities = 33/138 (23%), Positives = 61/138 (44%), Gaps = 12/138 (8%) Frame = +2 Query: 20 KMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEV 199 K+ + + + E D+L+ + +KE E + ++EQA V ++ Sbjct: 226 KLTQESVMDLENDKLQMEEKLKKKEFEMSQLNSKIEDEQAIVMQL--------------- 270 Query: 200 AQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLN------------KLT 343 QK EL+ ++ L+++L EAE + KV ++ LA +L+ +L Sbjct: 271 -QKKIKELQARIEELEEEL-EAERAARAKVEKQRSDLARELEELSERLEGAGGATAAQLE 328 Query: 344 QNVSKSAEMEKKVQDLEQ 397 N + AE K +DLE+ Sbjct: 329 MNKKREAEFLKLARDLEE 346
>TPR_HUMAN (P12270) Nucleoprotein TPR| Length = 2349 Score = 38.1 bits (87), Expect = 0.022 Identities = 47/186 (25%), Positives = 83/186 (44%), Gaps = 13/186 (6%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSA 184 +ALT K +E ++ Q ++ELEA R + E+ S +E++ Y T Sbjct: 90 KALTEKNKELEIAQDRNIAIQSQFTRTKEELEAEKRDLIRTNERLS-QELE---YLTEDV 145 Query: 185 DQL--EVAQKHAAELEVQVSALDQQLQEAEIHYKNK-VAEESEKLALVNTQLNKLTQNVS 355 +L ++ + + + E+Q+ + Q + + Y+ K + +E E L NT LN T+ + Sbjct: 146 KRLNEKLKESNTTKGELQLKLDELQASDVSVKYREKRLEQEKELLHSQNTWLN--TELKT 203 Query: 356 KSAEM-----EKKVQDLEQKLQL-----AYSKSDEQAKDAVVSTRSREFSLDSLTPQNKE 505 K+ E+ EK + LE K L S+ +EQ S + ++ L + KE Sbjct: 204 KTDELLALGREKGNEILELKCNLENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKE 263 Query: 506 QDLSQA 523 QA Sbjct: 264 AKEQQA 269 Score = 33.9 bits (76), Expect = 0.42 Identities = 29/119 (24%), Positives = 57/119 (47%), Gaps = 2/119 (1%) Frame = +2 Query: 170 KTYSADQLEVAQKHAAELEVQVSALDQQLQEAE--IHYKNKVAEESEKLALVNTQLNKLT 343 K + + EVAQ + +V L+++LQE E ++ + + + + K + +L K T Sbjct: 1207 KEIAETRFEVAQVESLRYRQRVELLERELQELEDSLNAEREKVQVTAKTMAQHEELMKKT 1266 Query: 344 QNVSKSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQ 520 + ++ E K +++ +++L+ D Q A V R+ LD L Q +LS+ Sbjct: 1267 ETMNVVMETNKMLREEKERLE-----QDLQQMQAKV----RKLELDILPLQEANAELSE 1316
>PCNT_HUMAN (O95613) Pericentrin (Pericentrin B) (Kendrin)| Length = 3336 Score = 38.1 bits (87), Expect = 0.022 Identities = 49/209 (23%), Positives = 86/209 (41%), Gaps = 21/209 (10%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQQLLEVRKELEA-------------AYRTIANQEEQASV 145 E L K LV E + L +QL + +E A A T A E A Sbjct: 1349 EVLAGKEDSEHRLVLELESLRRQLQQAAQEQAALREECTRLWSRGEATATDAEAREAALR 1408 Query: 146 REIKWDAYKTYSADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNT 325 +E++ D K S + + A+K + L Q+ L+ +L+E ++ A+++E + + Sbjct: 1409 KEVE-DLTKEQSETRKQ-AEKDRSALLSQMKILESELEE-QLSQHRGCAKQAEAVTALEQ 1465 Query: 326 QLNKLTQNV--------SKSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLD 481 Q+ L +++ ++AE E + ++ +Q++Q + + AK R Sbjct: 1466 QVASLDKHLRNQRQFMDEQAAEREHEREEFQQEIQRLEGQLRQAAKPQPWGPR------- 1518 Query: 482 SLTPQNKEQDLSQAPSTASVNPAQQQLRE 568 D QAP V QQ+LRE Sbjct: 1519 ---------DSQQAPLDGEVELLQQKLRE 1538
>CEP57_HUMAN (Q86XR8) Centrosomal protein of 57 kDa (Cep57 protein)| (Testis-specific protein 57) (Translokin) (FGF2-interacting protein) Length = 500 Score = 38.1 bits (87), Expect = 0.022 Identities = 38/144 (26%), Positives = 68/144 (47%), Gaps = 12/144 (8%) Frame = +2 Query: 62 LEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKHA--------- 214 L ++ +E +K L+ + N + + S + + + ++ + +K Sbjct: 97 LSRETIEYKKVLDEQIQERENSKNEESKHNQELTSQLLAAENKCNLLEKQLEYMRNMIKH 156 Query: 215 AELEVQVSALDQQ--LQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEMEKKVQD 388 AE+E + S L++Q L+ H + V + EKL L+ + NKLT + A EKK+Q+ Sbjct: 157 AEME-RTSVLEKQVSLERERQHDQTHVQSQLEKLDLLEQEYNKLT---TMQALAEKKMQE 212 Query: 389 LEQKL-QLAYSKSDEQAKDAVVST 457 LE KL + + QAK A + T Sbjct: 213 LEAKLHEEEQERKRMQAKAAELQT 236
>PLCB1_MOUSE (Q9Z1B3) 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase| beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C-beta-1) (PLC-beta-1) (PLC-I) (PLC-154) Length = 1216 Score = 38.1 bits (87), Expect = 0.022 Identities = 46/210 (21%), Positives = 98/210 (46%), Gaps = 21/210 (10%) Frame = +2 Query: 8 ALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSAD 187 AL ++M + L+ KD+ +QQLL +R+E + + + + ++++ D + + Sbjct: 996 ALDAEMTQ--KLIDLKDKQQQQLLNLRQEQYYSEKYQKREHIKLLIQKLT-DVAEECQNN 1052 Query: 188 QL----EVAQKHAAELEVQVSALDQQLQE--AEIHYKNKVAEESEKLALVNTQLNKLTQN 349 QL E+ +K EL+ +D++ QE E K+K E EK ++ + + ++ Q Sbjct: 1053 QLKKLKEICEKEKKELK---KKMDKKRQEKITEATSKDKSQMEEEKTEMIRSYIQEVVQY 1109 Query: 350 VSKSAEMEKKVQD-------------LEQKLQLAYSKSDE-QAKDAVVSTRSREFSLDSL 487 + + E + K Q+ L++K +L E Q K + EF +++ Sbjct: 1110 IKRLEEAQSKRQEKLVEKHNEIRQQILDEKPKLQTELEQEYQDKFKRLPLEILEFVQEAM 1169 Query: 488 TPQ-NKEQDLSQAPSTASVNPAQQQLREPS 574 + +++ + AP + + + A+ L+ PS Sbjct: 1170 KGKISEDSNHGSAPPSLASDAAKVNLKSPS 1199
>MYSP_ANISI (Q9NJA9) Paramyosin (Allergen Ani s 2)| Length = 869 Score = 38.1 bits (87), Expect = 0.022 Identities = 38/190 (20%), Positives = 92/190 (48%), Gaps = 11/190 (5%) Frame = +2 Query: 32 HANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKH 211 ++NL K++LE +L + +L+ + + +E+A+ + A + +L Q+H Sbjct: 647 NSNLTAIKNKLETELSTAQADLDEVTKELHAADERAN----RALADAARAVQELHEEQEH 702 Query: 212 AAE-------LEVQVSALDQQLQEAE----IHYKNKVAEESEKLALVNTQLNKLTQNVSK 358 + + LE QV L Q+QEAE + K +A+ ++ + L++ T+ + Sbjct: 703 SMKIDALRKSLEEQVKQLQVQIQEAEAAALLGGKRVIAKLETRIRDLEVALDEETR---R 759 Query: 359 SAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQAPSTAS 538 E + ++ +++++ + DE+ K V++ + + L+ L Q ++ ++A + + Sbjct: 760 HKETQSALRKKDRRIKEVQMQIDEEHKMFVMAQDTADRMLEKLNIQKRQLGEAEAMTMQN 819 Query: 539 VNPAQQQLRE 568 + ++ RE Sbjct: 820 LQRVRRYQRE 829
>MYH7_MESAU (P13540) Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta)| Length = 1934 Score = 38.1 bits (87), Expect = 0.022 Identities = 39/181 (21%), Positives = 83/181 (45%), Gaps = 35/181 (19%) Frame = +2 Query: 29 EHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQAS---------VREIKWDA----- 166 ++ +L+++K +++ L +++ E+E A + N EE+A E+K + Sbjct: 1718 QNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAH 1777 Query: 167 ----------------YKTYSADQLEV--AQKHAAELEVQVSALDQQLQEAEIHYKNKVA 292 ++ A+Q+ + +K +LE +V L+ +L EAE + + A Sbjct: 1778 LERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENEL-EAE---QKRNA 1833 Query: 293 EESEKLALVNTQLNKLTQNVSKSAEMEKKVQDLEQKLQL---AYSKSDEQAKDAVVSTRS 463 E + + ++ +LT + + ++QDL KLQL AY + E+A++ + S Sbjct: 1834 ESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLS 1893 Query: 464 R 466 + Sbjct: 1894 K 1894 Score = 31.2 bits (69), Expect = 2.7 Identities = 51/236 (21%), Positives = 86/236 (36%), Gaps = 47/236 (19%) Frame = +2 Query: 2 NEALTSKMQ----EHANLVHEKDQLEQQLLEVRKELEAAYRTIAN-QEEQASVREIKWDA 166 N LT+K + E + L + D LE L +V K+ A + N EE A + EI Sbjct: 932 NAELTAKKRKLEDECSELKRDIDDLELTLAKVEKDKHATENKVKNLTEEMAGLDEIIAKL 991 Query: 167 YKTYSA----------------DQLEVAQKHAAELEVQVSALDQQL-------------- 256 K A D++ K +LE QV L+ L Sbjct: 992 TKEKKALQEAHQQALDDLQAEEDKVNTLTKSKVKLEQQVDDLEGSLEQEKKVRMDLERAK 1051 Query: 257 ----------QEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEMEKKVQDLEQKLQ 406 QE+ + +N + EKL + +LN L + + ++Q ++LQ Sbjct: 1052 RKLEGDLKLTQESIMDLENDKQQLDEKLKKKDFELNALNARIEDEQALGSQLQKKLKELQ 1111 Query: 407 LAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKE--QDLSQAPSTASVNPAQQQLRE 568 + +E+ + + E L+ + +E + L +A SV + RE Sbjct: 1112 ARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKRE 1167
>PHLB2_HUMAN (Q86SQ0) Pleckstrin homology-like domain family B member 2 (Protein| LL5-beta) Length = 1253 Score = 38.1 bits (87), Expect = 0.022 Identities = 35/126 (27%), Positives = 54/126 (42%), Gaps = 16/126 (12%) Frame = +2 Query: 38 NLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQA-----SVREIKWDAYKTYSADQLEVA 202 N+V EK + + +L R++LE + Q+ Q S+RE K AD L+V Sbjct: 660 NIVGEKTKEKVKLDAEREKLERLQELYSEQKTQLDNCPESMREQLQQQLKR-DADLLDVE 718 Query: 203 QKHAAELEVQV----SALD-------QQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQN 349 KH +LE Q S LD QQL Y+ + EK++ + Q N + Q Sbjct: 719 SKHFEDLEFQQLEHESRLDEEKENLTQQLLREVAEYQRNIVSRKEKISALKKQANHIVQQ 778 Query: 350 VSKSAE 367 + + Sbjct: 779 AQREQD 784
>MYSP_SCHMA (P06198) Paramyosin| Length = 866 Score = 38.1 bits (87), Expect = 0.022 Identities = 47/192 (24%), Positives = 82/192 (42%), Gaps = 31/192 (16%) Frame = +2 Query: 2 NEALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTI----------ANQEEQASVRE 151 N+A + M+E+ NL LE L E R+ EAA + AN+ E+ Sbjct: 550 NKANANLMKENKNLSQRVKDLETFLDEERRLREAAENNLQITEHKRLQLANEIEEIRSTL 609 Query: 152 IKWDAYKTYSADQLEVAQKHAAELEVQVSAL--DQQLQEAEIHYKN---------KVAEE 298 + + ++ +LE AQ +EL +QV+ L D++ E +I K A E Sbjct: 610 ENLERLRKHAETELEEAQSRVSELTIQVNTLTNDKRRLEGDIGVMQADMDDAINAKQASE 669 Query: 299 SEKLALVNTQLN-----KLTQNVSKSAE-----MEKKVQDLEQKLQLAYSKSDEQAKDAV 448 + L N L + Q K AE +E +++++ KL+ A + + + + V Sbjct: 670 DRAIRLNNEVLRLADELRQEQGNYKHAEALRKQLEIEIREITVKLEEAEASATREGRRMV 729 Query: 449 VSTRSREFSLDS 484 ++R L+S Sbjct: 730 QKLQARVRELES 741 Score = 34.3 bits (77), Expect = 0.32 Identities = 38/151 (25%), Positives = 76/151 (50%), Gaps = 19/151 (12%) Frame = +2 Query: 35 ANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASV----REIKWDA--------YKTY 178 A L H K ++EQ+L E +ELE+ ++ E+ +V E+K+ + Y++ Sbjct: 479 AALNHLKSEMEQRLRERDEELESLRKSTTRTIEELTVTITEMEVKYKSELSRLKKRYESN 538 Query: 179 SAD---QLEVAQKHAAELEVQVSALDQQLQEAE--IHYKNKVAEESEKLALVNTQL--NK 337 AD QL+ A K A L + L Q++++ E + + ++ E +E N Q+ +K Sbjct: 539 IADLEIQLDTANKANANLMKENKNLSQRVKDLETFLDEERRLREAAEN----NLQITEHK 594 Query: 338 LTQNVSKSAEMEKKVQDLEQKLQLAYSKSDE 430 Q ++ E+ +++LE+ + A ++ +E Sbjct: 595 RLQLANEIEEIRSTLENLERLRKHAETELEE 625
>MYO6_MOUSE (Q64331) Myosin-6 (Myosin VI)| Length = 1265 Score = 38.1 bits (87), Expect = 0.022 Identities = 38/185 (20%), Positives = 72/185 (38%), Gaps = 10/185 (5%) Frame = +2 Query: 53 KDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKHAAELE-- 226 K ++ +Q+ + ++A + + ++DA S D L QK + E Sbjct: 867 KPEVNRQIKNLEISIDALMAKFTSTMMTREQIQKEYDALVKSSEDLLSALQKKKQQEEEA 926 Query: 227 -----VQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEMEKKVQDL 391 +Q ++ + E + + EE ++ L K + K E ++K Sbjct: 927 ERLRRIQEEMEKERKRREEDEERRRKEEEERRMKLEMEPKRKQEEEERKKREDDEKRIQS 986 Query: 392 EQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQ---DLSQAPSTASVNPAQQQL 562 E + QLA + +E + AV++ R+ L QN+ + D +Q PA Q Sbjct: 987 EVEAQLARQREEESQQQAVLAQECRDRELALRIAQNESELISDEAQGDMALRRGPAVQAT 1046 Query: 563 REPSG 577 + SG Sbjct: 1047 KAASG 1051
>CLPB_DEIRA (Q9RVI3) Chaperone clpB| Length = 852 Score = 38.1 bits (87), Expect = 0.022 Identities = 36/153 (23%), Positives = 68/153 (44%), Gaps = 16/153 (10%) Frame = +2 Query: 56 DQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKHAAELEVQV 235 D +++ +R LE++ I + EI+ +A K ++ +Q ++E Q+ Sbjct: 383 DLIDESAARLRMALESSPERIDQLSRRKLQLEIEREALKR---EKDVDSQNRLLDIENQL 439 Query: 236 SALDQQLQEAEIHYKNK------VAEESEKLALVNTQLNKLTQNVS----------KSAE 367 L +L E ++ + + E+ EKL V TQ+ K ++ + Sbjct: 440 KTLTDELNEVRSRWEAERGEVAALREKREKLDAVRTQIEKARRDYDLEEAARLEYGELPA 499 Query: 368 MEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSR 466 +EK VQDLE+KL+ A E ++ + + SR Sbjct: 500 LEKDVQDLEKKLKSAEFAHMEVTEEDIAAVVSR 532
>IE68_SHV21 (Q01042) Immediate-early protein| Length = 407 Score = 38.1 bits (87), Expect = 0.022 Identities = 31/153 (20%), Positives = 76/153 (49%), Gaps = 2/153 (1%) Frame = +2 Query: 80 EVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKHAAELEVQVSALDQQLQ 259 E +E EA + +E + + E + + + A++ E ++ A E E + A +++ + Sbjct: 94 EEAEEEEAEEKEAEEEEAEEAEEEAEEEEAEEAEAEEEEAEEEEAEEEEAE-EAEEEEAE 152 Query: 260 EAEIHYKNKVA-EESEKLALVNTQLNKLTQNVSKSAEMEKKVQDLEQKLQLAYSKSDEQA 436 EAE + + A EE+E+ A + + + ++ AE ++ ++ E++ + A +++E Sbjct: 153 EAEEEAEEEEAEEEAEEEAEEAEEAEEEAEEEAEEAEEAEEAEEAEEEAEEAEEEAEEAE 212 Query: 437 KDAVVSTRSREF-SLDSLTPQNKEQDLSQAPST 532 ++A + + E + + +E++ PST Sbjct: 213 EEAEEAEEAEEAEEAEEEAEEAEEEEEEAGPST 245 Score = 36.2 bits (82), Expect = 0.085 Identities = 30/142 (21%), Positives = 64/142 (45%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSA 184 EA + +E E++ E + E E E A A + E+ E + +A + + Sbjct: 105 EAEEEEAEEAEEEAEEEEAEEAEAEEEEAEEEEAEEEEAEEAEEEEAEEAEEEAEEEEAE 164 Query: 185 DQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSA 364 ++ E + A E E + ++ +EAE AEE+E+ A + + + ++ A Sbjct: 165 EEAEEEAEEAEEAEEEAEEEAEEAEEAE------EAEEAEEEAEEAEEEAEEAEEEAEEA 218 Query: 365 EMEKKVQDLEQKLQLAYSKSDE 430 E ++ ++ E++ + A + +E Sbjct: 219 EEAEEAEEAEEEAEEAEEEEEE 240
>MYSP_TAESA (Q8T305) Paramyosin| Length = 863 Score = 37.7 bits (86), Expect = 0.029 Identities = 45/168 (26%), Positives = 75/168 (44%), Gaps = 18/168 (10%) Frame = +2 Query: 41 LVHEKDQLEQQLLEVRKELE----AAYRTIANQEEQASVREIKWDA-----YKTYSAD-- 187 L H K ++EQ+L E +ELE + RTI S E+++ + K Y A Sbjct: 477 LNHLKSEMEQRLREKDEELENLRKSTTRTIEELTTTISEMEVRFKSDMSRLKKKYEATIS 536 Query: 188 ----QLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVS 355 QL+VA K A L + L Q++QE + A E E+ A + N L + Sbjct: 537 ELEVQLDVANKANANLNRENKTLAQRVQELQ------AALEDERRAREAAESN-LQVSER 589 Query: 356 KSAEMEKKVQDLEQKLQL---AYSKSDEQAKDAVVSTRSREFSLDSLT 490 K + +V+++ +L+L A ++ + DA S+++LT Sbjct: 590 KRIALASEVEEIRSQLELSDRARKNAESELNDANGRISELTLSVNTLT 637
>TPM_BOOMI (O97162) Tropomyosin| Length = 284 Score = 37.7 bits (86), Expect = 0.029 Identities = 29/130 (22%), Positives = 59/130 (45%), Gaps = 2/130 (1%) Frame = +2 Query: 20 KMQEHANLVHEK--DQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQL 193 KM EH ++ E+ D LE QL E R E A R + ++ E + + ++ Sbjct: 128 KMLEHRSITDEERMDGLEGQLKEARTMAEDADRKYDEVARKLAMVEADLER----AEERA 183 Query: 194 EVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEME 373 E + ELE ++ + L+ E+ + + +E + N+L + +++ E Sbjct: 184 ETGETKIVELEEELRVVGNNLKSLEVSEEKALQKEETYEMQIRQMTNRLQEAEARAEFAE 243 Query: 374 KKVQDLEQKL 403 + VQ L++++ Sbjct: 244 RSVQKLQKEV 253
>TPM2_DROME (P09491) Tropomyosin-2 (Tropomyosin I)| Length = 284 Score = 37.7 bits (86), Expect = 0.029 Identities = 40/157 (25%), Positives = 79/157 (50%), Gaps = 6/157 (3%) Frame = +2 Query: 53 KDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKHAAELEVQ 232 K +++ LE ++ A T NQ + A+ R K + +++ +K ++E+ Sbjct: 5 KKKMQAMKLEKDNAIDKA-DTCENQAKDANSRADKLN-------EEVRDLEKKFVQVEID 56 Query: 233 VSALDQQLQEA--EIHYKNKVAEESE-KLALVNTQLNKLTQNVSKSAEMEKKVQDLEQKL 403 + +QL++A E+ K K+ +E ++A N ++ ++ +++ KS E++ +QKL Sbjct: 57 LVTAKEQLEKANTELEEKEKLLTATESEVATQNRKVQQIEEDLEKS---EERSTTAQQKL 113 Query: 404 QLAYSKSDEQAKDA-VVSTRSR--EFSLDSLTPQNKE 505 A +DE + V+ RS+ E +D LT Q KE Sbjct: 114 LEATQSADENNRMCKVLENRSQQDEERMDQLTNQLKE 150
>MYH1_MOUSE (Q5SX40) Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1)| Length = 1942 Score = 37.7 bits (86), Expect = 0.029 Identities = 45/207 (21%), Positives = 86/207 (41%), Gaps = 19/207 (9%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKW-------- 160 E + ++ A ++ L ++L E+ + LE A + Q E RE ++ Sbjct: 1127 EEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLE 1186 Query: 161 DAYKTYSADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKL 340 +A + A + +KHA V+ L +Q+ + K K+ +E ++ + L Sbjct: 1187 EATLQHEATAATLRKKHADS----VAELGEQIDNLQ-RVKQKLEKEKSEMKMEIDDLASN 1241 Query: 341 TQNVSKS-AEMEKKVQDLEQKLQLAYSKSDEQ--------AKDAVVSTRSREFS--LDSL 487 + +SKS +EK + LE ++ +K +EQ A+ + T S E+S LD Sbjct: 1242 MEVISKSKGNLEKMCRTLEDQVSELKTKEEEQQRLINELTAQRGRLQTESGEYSRQLDEK 1301 Query: 488 TPQNKEQDLSQAPSTASVNPAQQQLRE 568 + + T + ++QL E Sbjct: 1302 DSLVSQLSRGKQAFTQQIEELKRQLEE 1328
>MOES_MOUSE (P26041) Moesin (Membrane-organizing extension spike protein)| Length = 576 Score = 37.7 bits (86), Expect = 0.029 Identities = 42/172 (24%), Positives = 72/172 (41%), Gaps = 24/172 (13%) Frame = +2 Query: 26 QEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQE---------------EQASVREIKW 160 +E L+ + Q+E+Q + ++ELE R E E+ E K Sbjct: 341 REKEELMEKLKQIEEQTKKAQQELEEQTRRALELEQERKRAQSEAEKLAKERQEAEEAK- 399 Query: 161 DAYKTYSADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKL 340 +A S DQ + ++ A+E+ +++A QL+ A +++ E +K +V L K Sbjct: 400 EALLQASRDQKKTQEQLASEM-AELTARISQLEMARKKKESEAVEWQQKAQMVQEDLEKT 458 Query: 341 ---------TQNVSKSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSRE 469 T +V++ AE E QD A ++D AKD R+ E Sbjct: 459 RAELKTAMSTPHVAEPAENEHDEQDENGAEASAELRADAMAKDRSEEERTTE 510
>CLPB_PLEBO (O87444) Chaperone clpB| Length = 873 Score = 37.7 bits (86), Expect = 0.029 Identities = 47/195 (24%), Positives = 84/195 (43%), Gaps = 10/195 (5%) Frame = +2 Query: 11 LTSKMQEHANLVHEKDQLEQQLLEVRKE--------LEAAYRTIANQEEQASVREIKWDA 166 +TSK +E + + QLE + L ++KE LE R +A+ +E S +W A Sbjct: 408 ITSKPEELDEVDRKVLQLEMERLSLQKENDAGSRDRLERLERELADFKEDQSKLNAQWQA 467 Query: 167 YKTYSADQLEVAQK-HAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLT 343 K+ D ++ ++ LE+Q + D L A K+ E + K+ +QL++ Sbjct: 468 EKSVITDLQKLKEEIDRVNLEIQQAERDYDLNRAAELKYGKLNELNRKVEETESQLSQ-- 525 Query: 344 QNVSKSAEMEKKVQDLEQKLQLAYSK-SDEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQ 520 + KS + + LE + SK + V S + LD + Q + + Q Sbjct: 526 --IQKSGATLLREEVLESDIAEIISKWTGIPVSKLVESEMQKLLQLDDVLHQ---RVIGQ 580 Query: 521 APSTASVNPAQQQLR 565 + +V+ A Q+ R Sbjct: 581 DEAVTAVSDAIQRSR 595
>MYO2_SCHPO (Q9USI6) Myosin type-2 heavy chain 1 (Myosin type II heavy chain 1)| Length = 1526 Score = 37.7 bits (86), Expect = 0.029 Identities = 26/140 (18%), Positives = 65/140 (46%), Gaps = 7/140 (5%) Frame = +2 Query: 71 QLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKHAAELEVQVSALDQ 250 +L E+ + L + N +++ ++ + K + E+++KH ++ + Sbjct: 1152 ELQEIHENLLLKVSDLENYKKKYEGLQLDLEGLKDVDTNFQELSKKHR-----DLTFNHE 1206 Query: 251 QLQEAEIHYKNKVA-------EESEKLALVNTQLNKLTQNVSKSAEMEKKVQDLEQKLQL 409 L YK K++ + S K++ + Q+N+L+ SK E+E+K+ +L + Sbjct: 1207 SLLRQSASYKEKLSLASSENKDLSNKVSSLTKQVNELSPKASKVPELERKITNLMHEYSQ 1266 Query: 410 AYSKSDEQAKDAVVSTRSRE 469 +++ + A++++R E Sbjct: 1267 LGKTFEDEKRKALIASRDNE 1286
>SNX23_HUMAN (Q96L93) Kinesin-like motor protein C20orf23 (Sorting nexin 23)| Length = 1317 Score = 37.7 bits (86), Expect = 0.029 Identities = 40/178 (22%), Positives = 76/178 (42%), Gaps = 1/178 (0%) Frame = +2 Query: 50 EKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKHAAELEV 229 E ++++Q++ RKE E I QEE R + D L +K E Sbjct: 629 ELERMQQEVETQRKETEIVQLQIRKQEESLKRRSFH---IENKLKDLLAEKEKFEEERLR 685 Query: 230 QVSALDQQLQEAEIHYKNKVAEESEKL-ALVNTQLNKLTQNVSKSAEMEKKVQDLEQKLQ 406 + ++ Q + E +V EE ++L L N + + Q + +++K+ + KL+ Sbjct: 686 EQQEIELQKKRQEEETFLRVQEELQRLKELNNNEKAEKFQIFQELDQLQKEKDEQYAKLE 745 Query: 407 LAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQAPSTASVNPAQQQLREPSGI 580 L + +EQ K+ V+ E L ++Q++ Q V +++ R+ GI Sbjct: 746 LEKKRLEEQEKEQVMLVAHLEEQL------REKQEMIQLLRRGEVQWVEEEKRDLEGI 797
>PLST_CARAU (P31393) Plasticin| Length = 453 Score = 37.7 bits (86), Expect = 0.029 Identities = 35/168 (20%), Positives = 78/168 (46%), Gaps = 1/168 (0%) Frame = +2 Query: 2 NEALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDA-YKTY 178 N+ S +++ +L + +L +L + + + + + I N+ Q +RE++ Sbjct: 85 NDRFASFIEKVRHLEQQNSKLILELGQYKDQHQGSTGRI-NELCQQEMRELRRQLELMAK 143 Query: 179 SADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSK 358 DQ++V + + AE V+ L+Q+L E K E L L ++ T Sbjct: 144 DRDQMQVERDNLAE---DVALLNQRLNEE----MGKRQEAENNLTLFRKDVDDATL---A 193 Query: 359 SAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNK 502 E+E+K++ L +++ DE+ +D VS +S++ ++ + ++ Sbjct: 194 RLELERKIESLMDEIEFLKKMHDEEIQDVQVSVQSQQMKMEVMETSSR 241
>PKHA6_HUMAN (Q9Y2H5) Pleckstrin homology domain-containing family A member 6| (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3) Length = 1048 Score = 37.7 bits (86), Expect = 0.029 Identities = 31/134 (23%), Positives = 61/134 (45%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSA 184 + L K+ E +V E+D+L QQL ++ LE+A + E + AY Sbjct: 531 DKLLGKLCEQNKVVREQDRLVQQLRAEKESLESALMGTHQELEMFGSQ----PAYPEKLR 586 Query: 185 DQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSA 364 + + Q + V++S L + I Y++ +E S + QLN TQN + Sbjct: 587 HKKDSLQNQLINIRVELSQATTALTNSTIEYEHLESEVSALHDDLWEQLNLDTQNEVLNR 646 Query: 365 EMEKKVQDLEQKLQ 406 +++K++ ++ ++ Sbjct: 647 QIQKEIWRIQDVME 660
>HOOK2_MOUSE (Q7TMK6) Hook homolog 2| Length = 716 Score = 37.7 bits (86), Expect = 0.029 Identities = 38/128 (29%), Positives = 60/128 (46%), Gaps = 6/128 (4%) Frame = +2 Query: 2 NEALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIAN-----QEEQASVREI-KWD 163 N+ALTS QE L E D+L Q E ++LEA + QE + VR++ + + Sbjct: 280 NQALTSLSQEAQALKDEMDELRQS-SERARQLEATLNSCRRRLGELQELRRQVRQLEERN 338 Query: 164 AYKTYSADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLT 343 A QLE + A L Q+ A +Q+QE + ++ + A ++EK L + Sbjct: 339 AGHAERTRQLEEELRRAGSLRAQLEAQRRQVQELQGQWQEE-AMKAEKWLFECRNLEEKC 397 Query: 344 QNVSKSAE 367 V+K E Sbjct: 398 DLVTKEKE 405
>D7_DICDI (P54682) cAMP-inducible prespore protein D7 precursor| Length = 850 Score = 37.7 bits (86), Expect = 0.029 Identities = 46/189 (24%), Positives = 86/189 (45%), Gaps = 9/189 (4%) Frame = +2 Query: 29 EHANLVHEKDQLEQ-QLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSA-DQLEVA 202 E+ + +E+D +EQ Q L+ + E A Q E A + E + DA K + DQLE+ Sbjct: 646 ENNEITNEQDAIEQAQHLQRIENGEDIDEYEAAQHEVAFLDENEQDAAKLQNEMDQLELL 705 Query: 203 QKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEMEKKV 382 + E + L QQL E E N+ ++ ++ ++ + + E +++ Sbjct: 706 LEENEEEQFSNKNL-QQLNENE----NQQQQQGQQQVQATNVEQQIVEQLKVIKEFQRQD 760 Query: 383 QDLEQKLQ----LAYSKSDEQAK---DAVVSTRSREFSLDSLTPQNKEQDLSQAPSTASV 541 Q +QK+Q Y E+A+ DA ++ +++ + D Q K+Q Q + Sbjct: 761 QQKKQKIQQENDAVYLSDVEKAQLELDAELAKNNKQENQDENLVQEKQQSPDQIKNQLKN 820 Query: 542 NPAQQQLRE 568 +QQ++E Sbjct: 821 IQHEQQIQE 829
>YBY0_YEAST (P38272) Protein YBR130C| Length = 425 Score = 37.7 bits (86), Expect = 0.029 Identities = 41/170 (24%), Positives = 81/170 (47%), Gaps = 9/170 (5%) Frame = +2 Query: 17 SKMQEHANLVHEKDQLEQQLLEVR----KELEAAYRTIANQ-EEQASVREIKWDAYKTYS 181 SK+ E+ NL+ +++ + E + KELE Y ++N+ EQ + K S Sbjct: 82 SKLLENLNLLKNENENLNSIFERKNKKLKELEKDYSELSNRYNEQKEKMDQLSKLAKNSS 141 Query: 182 ADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQN---- 349 A + ++K +EV ++L + HY +++++ +EK+ L+ +L+ N Sbjct: 142 AIEQSCSEK-LQNMEVNYNSLLESQNLYRDHYSDEISKLNEKIGLLELELSNQNLNYGSD 200 Query: 350 VSKSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQN 499 S ++++E + ++ KS E KD+ +S + SLD L Q+ Sbjct: 201 TSSNSDIELNLNKFNDSVK--DLKSLETEKDSKLS-KIITHSLDELNLQS 247
>RAD50_HALSA (Q9HRW3) DNA double-strand break repair rad50 ATPase| Length = 883 Score = 37.7 bits (86), Expect = 0.029 Identities = 25/78 (32%), Positives = 39/78 (50%), Gaps = 9/78 (11%) Frame = +2 Query: 278 KNKVAEESEKLALVNTQLNKLTQNVSKSAEM---EKKVQDLEQKLQLAYSKSDEQA---- 436 + +VAE +LA V +L+ + Q V + + E +V DLEQ+ + A + DEQA Sbjct: 474 RERVAELDAELADVEDELDAVAQRVDRGESLVAAEDRVDDLEQQRERAVERRDEQADIAD 533 Query: 437 --KDAVVSTRSREFSLDS 484 +D R R LD+ Sbjct: 534 AKRDQAAEKRDRAADLDA 551
>SMC1A_MOUSE (Q9CU62) Structural maintenance of chromosome 1-like 1 protein| (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8) Length = 1233 Score = 37.7 bits (86), Expect = 0.029 Identities = 39/170 (22%), Positives = 76/170 (44%), Gaps = 8/170 (4%) Frame = +2 Query: 20 KMQEHANLVHEK-----DQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSA 184 K +HA ++K D+LE+++L V K + + +E Q+ R++ + + Sbjct: 317 KSLQHAQKHYKKRKGDMDELEKEMLSVEKARQE-FEERMEEESQSQGRDLTLEENQVKKY 375 Query: 185 DQL-EVAQKHAAEL--EVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVS 355 +L E A K AA L E++ DQ+ + + + + E+E K+ Q + Sbjct: 376 HRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEERKKVETEA---------KIKQKLR 426 Query: 356 KSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKE 505 + E +K+++ LE+ + + +EQ K T E + + NKE Sbjct: 427 EIEENQKRIEKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRRIDEINKE 476
>MYSU_RABIT (Q99105) Myosin heavy chain, embryonic smooth muscle isoform| (Fragment) Length = 501 Score = 37.4 bits (85), Expect = 0.038 Identities = 43/181 (23%), Positives = 77/181 (42%), Gaps = 7/181 (3%) Frame = +2 Query: 41 LVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKH--- 211 L+ EK +LE ++ ++ +ELE + ++ ++ D A + AQK Sbjct: 252 LLDEKRRLEARMRQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNA 311 Query: 212 AAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQL-NKLTQNVSKSAEMEKKVQD 388 +LE Q L +LQE E K+K L QL +L Q + A K V+ Sbjct: 312 RQQLERQNKDLKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRR 371 Query: 389 LEQKLQLAYSKSDEQAKDAVVSTRSREFS---LDSLTPQNKEQDLSQAPSTASVNPAQQQ 559 E+KL+ + + +++ + A E + + L Q +E + + AS Q++ Sbjct: 372 TEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRE 431 Query: 560 L 562 L Sbjct: 432 L 432 Score = 36.6 bits (83), Expect = 0.065 Identities = 43/188 (22%), Positives = 82/188 (43%), Gaps = 15/188 (7%) Frame = +2 Query: 50 EKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKHAAELEV 229 E + E + L + + LE A A +E + ++++ D S+ + K+ ELE Sbjct: 2 EAREKETKALSLSRALEEALE--AKEEFERQNKQLRADMEDLMSSK--DDVGKNVHELEK 57 Query: 230 QVSALDQQLQE-----AEIHYKNKVAEESEKLALVNTQLNKL----------TQNVSKSA 364 AL+QQ++E E+ + + E+++ VNTQ K Q+ K Sbjct: 58 SKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNTQAMKAQFERDLQARDEQSEEKKR 117 Query: 365 EMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQAPSTASVN 544 + K+V++LE +L+ +Q AV S + E L L Q + + ++ + Sbjct: 118 LLTKQVRELEAELE----DERKQRALAVASKKKMEIDLKDLEAQIEAANKARERRVKQLR 173 Query: 545 PAQQQLRE 568 Q Q+++ Sbjct: 174 RLQAQMKD 181
>MOES_RAT (O35763) Moesin (Membrane-organizing extension spike protein)| Length = 576 Score = 37.4 bits (85), Expect = 0.038 Identities = 42/171 (24%), Positives = 71/171 (41%), Gaps = 23/171 (13%) Frame = +2 Query: 26 QEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQE---------------EQASVREIKW 160 +E L+ + Q+E+Q + ++ELE R E E+ E K Sbjct: 341 REKEELMEKLKQIEEQTKKAQQELEEQTRRALELEQERKRAQSEAEKLAKERQEAEEAK- 399 Query: 161 DAYKTYSADQLEVAQKHA---AELEVQVSALD-----QQLQEAEIHYKNKVAEESEKLAL 316 +A S DQ + ++ A AEL +VS L+ ++ + E H K ++ +E + Sbjct: 400 EALLQASRDQKKTQEQLASEMAELTARVSQLEMARKKKESEAEECHQKAQMVQEDLEKTR 459 Query: 317 VNTQLNKLTQNVSKSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSRE 469 + T +V++ AE E QD A ++D AKD R+ E Sbjct: 460 AELKTAMSTPHVAEPAENEHDEQDENGAEASAELRADAMAKDRSEEERTTE 510
>SMC4_YEAST (Q12267) Structural maintenance of chromosome 4| Length = 1418 Score = 37.4 bits (85), Expect = 0.038 Identities = 29/124 (23%), Positives = 55/124 (44%), Gaps = 6/124 (4%) Frame = +2 Query: 50 EKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKHAAELEV 229 E D++E++L E A T+ EE+ K ++ Q+ A+ A L Sbjct: 850 EVDKIERELSERENNFRVASDTVHEMEEELK----KLRDHEPDLESQISKAEMEADSLAS 905 Query: 230 QVSALDQQLQEAEIHYKNKVAEESE------KLALVNTQLNKLTQNVSKSAEMEKKVQDL 391 +++ +QQ++EAE+ Y V+++++ L + + N L E K +QD Sbjct: 906 ELTLAEQQVKEAEMAYVKAVSDKAQLNVVMKNLERLRGEYNDLQSETKTKKEKIKGLQDE 965 Query: 392 EQKL 403 K+ Sbjct: 966 IMKI 969
>GCC1_MOUSE (Q9D4H2) GRIP and coiled-coil domain-containing protein 1 (Golgi| coiled coil protein 1) Length = 778 Score = 37.4 bits (85), Expect = 0.038 Identities = 39/176 (22%), Positives = 80/176 (45%), Gaps = 22/176 (12%) Frame = +2 Query: 20 KMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEV 199 + +HA ++ E +L Q+ R++LE + +E + ++ A + Y+ADQ+E Sbjct: 239 EQSDHALMLRELQKLLQEERTQRQDLE-----LRLEETREAL------AGRAYAADQVEG 287 Query: 200 AQKHAAELEVQVSAL--------------DQQLQEAE-------IHYKNKVAEESEKLAL 316 + +L +V L D +LQE + H++ ++ +E K AL Sbjct: 288 FELQTKQLTREVEELKGELQTIRDEKNRPDPRLQELQQEAARLKSHFQAQLQQEMRKTAL 347 Query: 317 VNTQLNKLTQ-NVSKSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLD 481 QL + +Q + A +E ++ ++ + L Y K+ ++ + A+ + R LD Sbjct: 348 AEDQLRQQSQVEEQRVAALESQISEVSELLG-TYEKAKQKDQLAIQKLKERLLQLD 402
>OPTN_XENLA (Q5M7B7) Optineurin| Length = 532 Score = 37.4 bits (85), Expect = 0.038 Identities = 42/163 (25%), Positives = 70/163 (42%), Gaps = 7/163 (4%) Frame = +2 Query: 2 NEALTSK--MQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKT 175 NEA K +QE L+ ++ Q Q LE ++ L + + + Q E EIK + KT Sbjct: 283 NEAKQFKNSLQEKCILLDKRLQENQVDLEEKQSLRYSIKKLELQVESQE-SEIKLEQNKT 341 Query: 176 YSADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVA-----EESEKLALVNTQLNKL 340 E + L+V L+ + QE I KV+ E EKL + L K Sbjct: 342 ------EAEKNQLGILQVSYDKLNSEYQELRIREIEKVSKVEFNELLEKLDVCEKALAKK 395 Query: 341 TQNVSKSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSRE 469 + + EM+ K ++ ++ ++L ++ D D +RE Sbjct: 396 QFEIDEMREMDTKHEEDKETIELLRAQVDVYCADFHAERSARE 438
>K1C19_RAT (Q63279) Keratin, type I cytoskeletal 19 (Cytokeratin-19) (CK-19)| (Keratin-19) (K19) (Type I keratin Ka19) Length = 403 Score = 37.4 bits (85), Expect = 0.038 Identities = 30/123 (24%), Positives = 64/123 (52%), Gaps = 5/123 (4%) Frame = +2 Query: 53 KDQLEQQLLEVRKELEAAYRTIANQEEQASVR-----EIKWDAYKTYSADQLEVAQKHAA 217 + LE Q+ +++EL AY ++EE +++R ++ + T D ++ + + Sbjct: 200 RTDLEMQIENLKEEL--AYLKKNHEEEISALRSQVGGQVSVEVDSTPGIDLAKILSEMRS 257 Query: 218 ELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEMEKKVQDLEQ 397 + E ++ ++AE Y ++ E + ++A+ TQ+ N ++ E+ +KVQDLE Sbjct: 258 QYEAMA---EKNRKDAEAWYLTQIDELNTQVAVHTTQIQI---NKTEVTELRRKVQDLEI 311 Query: 398 KLQ 406 +LQ Sbjct: 312 ELQ 314
>GRAP1_MOUSE (Q8VD04) GRIP1-associated protein 1 (GRASP-1) (HCMV-interacting| protein) Length = 806 Score = 37.4 bits (85), Expect = 0.038 Identities = 29/121 (23%), Positives = 60/121 (49%), Gaps = 1/121 (0%) Frame = +2 Query: 80 EVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKHAAE-LEVQVSALDQQL 256 ++++ELEAA +++A +Q ++ A DQ++ A+ L Q S L +L Sbjct: 276 KLQQELEAANQSLAELRDQRQGERLEHAAALRALQDQIQTAKTQELNMLREQTSELASEL 335 Query: 257 QEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEMEKKVQDLEQKLQLAYSKSDEQA 436 Q + Y+ + ++ + + + L ++ + + E+ ++ + L Q LQ A KS E+ Sbjct: 336 QHRQAEYEELMGQKDDLNSQLQESLRANSRLLEQLQEIGQEKEQLTQDLQEA-RKSAEKR 394 Query: 437 K 439 K Sbjct: 395 K 395
>SMC1A_HUMAN (Q14683) Structural maintenance of chromosome 1-like 1 protein| (SMC1alpha protein) (DXS423E protein) (Sb1.8) Length = 1233 Score = 37.4 bits (85), Expect = 0.038 Identities = 36/170 (21%), Positives = 76/170 (44%), Gaps = 3/170 (1%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSA 184 ++L + + + + D+LE+++L V K + + +E Q+ R++ + + Sbjct: 317 KSLQNAQKHYKKRKGDMDELEKEMLSVEKARQE-FEERMEEESQSQGRDLTLEENQVKKY 375 Query: 185 DQL-EVAQKHAAEL--EVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVS 355 +L E A K AA L E++ DQ+ + + + + E+E K+ Q + Sbjct: 376 HRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEERKKVETEA---------KIKQKLR 426 Query: 356 KSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKE 505 + E +K+++ LE+ + + +EQ K T E + + NKE Sbjct: 427 EIEENQKRIEKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRRIDEINKE 476
>SMC1A_BOVIN (O97593) Structural maintenance of chromosome 1-like 1 protein| (SMC-protein) Length = 1233 Score = 37.4 bits (85), Expect = 0.038 Identities = 36/170 (21%), Positives = 76/170 (44%), Gaps = 3/170 (1%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSA 184 ++L + + + + D+LE+++L V K + + +E Q+ R++ + + Sbjct: 317 KSLQNAQKHYKKRKGDMDELEKEMLSVEKARQE-FEERMEEESQSQGRDLTLEENQVKKY 375 Query: 185 DQL-EVAQKHAAEL--EVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVS 355 +L E A K AA L E++ DQ+ + + + + E+E K+ Q + Sbjct: 376 HRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEERKKVETEA---------KIKQKLR 426 Query: 356 KSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKE 505 + E +K+++ LE+ + + +EQ K T E + + NKE Sbjct: 427 EIEENQKRIEKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRRIDEINKE 476
>MYO5B_RAT (P70569) Myosin-5B (Myosin Vb) (Myosin heavy chain myr 6)| Length = 1846 Score = 37.4 bits (85), Expect = 0.038 Identities = 30/142 (21%), Positives = 59/142 (41%), Gaps = 1/142 (0%) Frame = +2 Query: 11 LTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQ 190 L + + NLV E QLEQ+ +R E + + + + + + T Sbjct: 1063 LEEERSRYQNLVKEYSQLEQRYENLRDEQQTPGHRKNPSNQSSLESDSNYPSISTSEIGD 1122 Query: 191 LEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSK-SAE 367 E A + E+ ++ +A+D + + + +V E ++ + QL K Q+ K E Sbjct: 1123 TEDALQQVEEIGIEKAAMDMTV---FLKLQKRVRELEQERKKLQVQLEKEQQDSKKVQVE 1179 Query: 368 MEKKVQDLEQKLQLAYSKSDEQ 433 + D++Q +AY+ Q Sbjct: 1180 QQNNGLDVDQDADIAYNSLKRQ 1201
>MOES_HUMAN (P26038) Moesin (Membrane-organizing extension spike protein)| Length = 576 Score = 37.0 bits (84), Expect = 0.050 Identities = 42/172 (24%), Positives = 71/172 (41%), Gaps = 24/172 (13%) Frame = +2 Query: 26 QEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQE---------------EQASVREIKW 160 +E L+ Q+E+Q + ++ELE R E E+ E K Sbjct: 341 REKEELMERLKQIEEQTKKAQQELEEQTRRALELEQERKRAQSEAEKLAKERQEAEEAK- 399 Query: 161 DAYKTYSADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKL 340 +A S DQ + ++ A E+ +++A QL+ A +++ E +K +V L K Sbjct: 400 EALLQASRDQKKTQEQLALEM-AELTARISQLEMARQKKESEAVEWQQKAQMVQEDLEKT 458 Query: 341 ---------TQNVSKSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSRE 469 T +V++ AE E+ QD A ++D AKD R+ E Sbjct: 459 RAELKTAMSTPHVAEPAENEQDEQDENGAEASADLRADAMAKDRSEEERTTE 510
>GOGA5_MOUSE (Q9QYE6) Golgin subfamily A member 5 (Golgin-84) (Sumiko protein)| (Ret-II protein) Length = 729 Score = 37.0 bits (84), Expect = 0.050 Identities = 42/182 (23%), Positives = 88/182 (48%), Gaps = 6/182 (3%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSA 184 EA+T ++++ + D+L+QQ+ R LE+A + + + +++A+ R ++ S Sbjct: 389 EAVTLAERKYSEEKKKVDELQQQVKLHRASLESAKQELVDYKQKAT-RILQ-------SK 440 Query: 185 DQLEVAQKHAAELEVQVSALDQQLQEAEI-HYKNKVAEESEKLALVNTQL-----NKLTQ 346 ++L + K + E S+ ++ E+ H K EE +KL QL + Q Sbjct: 441 EKLINSLKEGSSFEGLESSTASSMELEELRHEKEMQKEEIQKLMGQMHQLRSELQDMEAQ 500 Query: 347 NVSKSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQAP 526 VS++ +++QDL+ Q+A ++ +Q + + +EF + E+DL + Sbjct: 501 QVSEAESAREQLQDLQD--QIAKQRTSKQELETELERMKQEF-------RYMEEDLHRTK 551 Query: 527 ST 532 +T Sbjct: 552 NT 553
>RAD50_RAT (Q9JIL8) DNA repair protein RAD50 (EC 3.6.-.-)| Length = 1312 Score = 37.0 bits (84), Expect = 0.050 Identities = 32/129 (24%), Positives = 59/129 (45%), Gaps = 12/129 (9%) Frame = +2 Query: 92 ELEAAYRTIANQEEQASVREIKWDAYKTYSAD--QLEVAQKHAAELEVQVSALDQQLQ-- 259 E+ +A R I + VR+ + K + L ++ A E+ Q+++ + QL Sbjct: 178 EIFSATRYIKALDTLRQVRQTQGQKVKECQTELKYLRQNKEKACEIRDQITSKEAQLASS 237 Query: 260 -------EAEIH-YKNKVAEESEKLALVNTQLNKLTQNVSKSAEMEKKVQDLEQKLQLAY 415 E E+ KN++ E L+ + N++ S+ +MEK +LEQK++ + Sbjct: 238 REIVKAYENELEPLKNRLKEIEHNLSKIMRLDNEIKALDSRKKQMEKDNSELEQKMEKVF 297 Query: 416 SKSDEQAKD 442 +DEQ D Sbjct: 298 QGTDEQLND 306
>NGAP_HUMAN (Q9UJF2) Ras GTPase-activating protein nGAP (RAS protein| activator-like 1) Length = 1139 Score = 37.0 bits (84), Expect = 0.050 Identities = 42/194 (21%), Positives = 79/194 (40%), Gaps = 5/194 (2%) Frame = +2 Query: 2 NEALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYS 181 + A S ++ A V Q E+ + E + L+ A ++E ++E Sbjct: 949 DSATMSPVERTAAWVLNNGQYEEDVEETEQNLDEAKHAEKYEQEITKLKE---------- 998 Query: 182 ADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLAL----VNTQLNKLTQN 349 +L V+ + E E ++ +QQ+Q+ + YK ++ + E+L ++Q+ + Sbjct: 999 --RLRVSSRRLEEYERRLLVQEQQMQKLLLEYKARLEDSEERLRRQQEEKDSQMKSIISR 1056 Query: 350 VSKSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQAPS 529 + E KK Q + A K + + +VS S L S Q KE+ Q + Sbjct: 1057 LMAVEEELKKDHAEMQAVIDAKQKIIDAQEKRIVSLDSANTRLMSALTQVKERYSMQVRN 1116 Query: 530 TAS-VNPAQQQLRE 568 S NP + + E Sbjct: 1117 GISPTNPTKLSITE 1130
>GOGB1_HUMAN (Q14789) Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372| kDa Golgi complex-associated protein) (GCP372) Length = 3259 Score = 37.0 bits (84), Expect = 0.050 Identities = 41/150 (27%), Positives = 73/150 (48%), Gaps = 15/150 (10%) Frame = +2 Query: 2 NEALTSKMQ----EHANLVH--EKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWD 163 N+ L+ ++Q EH L + E ++ E ++L + ELE A R ++ Q + + Sbjct: 289 NQILSQQLQQMEAEHNTLRNTVETEREESKILLEKMELEVAERKLSFHNLQEEMHHL--- 345 Query: 164 AYKTYSADQLEVAQKHAAELEVQVSALDQQLQEAEIHYK-------NKVAEESEKLA-LV 319 +Q E A + AELE + SAL+Q+ +AE+ K K +E + + Sbjct: 346 ------LEQFEQAGQAQAELESRYSALEQK-HKAEMEEKTSHILSLQKTGQELQSACDAL 398 Query: 320 NTQLNKLTQNVSKSA-EMEKKVQDLEQKLQ 406 Q +KL Q+ ++ A + + +Q LE +LQ Sbjct: 399 KDQNSKLLQDKNEQAVQSAQTIQQLEDQLQ 428 Score = 34.7 bits (78), Expect = 0.25 Identities = 41/186 (22%), Positives = 77/186 (41%), Gaps = 23/186 (12%) Frame = +2 Query: 26 QEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDA----YK------- 172 + H +++ EKDQL Q+ +L+ R + + + + K DA Y+ Sbjct: 2485 ERHLSIILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVI 2544 Query: 173 ----TYSADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKL 340 + LEV + ELE + + L+++L+E+E E +E L L + Sbjct: 2545 TIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESE--------EANEDLRRSFNALQEE 2596 Query: 341 TQNVSKSAE--------MEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQ 496 Q++SK E + ++V L+++ L + + K+ V S FS Sbjct: 2597 KQDLSKEIESLKVSISQLTRQVTALQEEGTLGLYHAQLKVKEEEVHRLSALFSSSQKRIA 2656 Query: 497 NKEQDL 514 E++L Sbjct: 2657 ELEEEL 2662 Score = 34.3 bits (77), Expect = 0.32 Identities = 40/168 (23%), Positives = 67/168 (39%), Gaps = 18/168 (10%) Frame = +2 Query: 59 QLEQQLLEVRKELEAAYRT-------IANQEEQASVREIKWDAYKTYSADQLEVAQKHAA 217 QLE L E ++ Y + + Q S+ D ++L+ Q + Sbjct: 768 QLEMNLAEAERQRRLDYESQTAHDNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFS 827 Query: 218 ELEVQVSALDQQLQ--EAEI--------HYKNKVAEESEKLALVNTQLNKLTQ-NVSKSA 364 E + +L QLQ E+E+ H +KV E S+ L+ ++ K+ Q + K Sbjct: 828 EQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKR 887 Query: 365 EMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQ 508 ++E Q +E+K Q S + +V +FSL KEQ Sbjct: 888 DVETLQQTIEEKDQQVTEISFSMT-EKMVQLNEEKFSLGVEIKTLKEQ 934 Score = 32.7 bits (73), Expect = 0.94 Identities = 36/148 (24%), Positives = 67/148 (45%), Gaps = 6/148 (4%) Frame = +2 Query: 17 SKMQEHANLVHEKDQ----LEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSA 184 S +E L+ EK Q L++ + ++++ A RT+ E + + + K A Sbjct: 2005 SHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLA 2064 Query: 185 DQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKS- 361 +E +K AEL LD EA ++ N +L K Q+ +S Sbjct: 2065 QAVEHRKKAQAELASFKVLLDDTQSEA------------ARVLADNLKLKKELQSNKESV 2112 Query: 362 -AEMEKKVQDLEQKLQLAYSKSDEQAKD 442 ++M++K +DLE++L+ A K ++ K+ Sbjct: 2113 KSQMKQKDEDLERRLEQAEEKHLKEKKN 2140 Score = 32.3 bits (72), Expect = 1.2 Identities = 35/183 (19%), Positives = 82/183 (44%), Gaps = 11/183 (6%) Frame = +2 Query: 59 QLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKHAAELEVQVS 238 +++Q+L ++++LE ++ + + + + + A + + + Q+ AE + Sbjct: 249 EMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNTLRN 308 Query: 239 ALDQQLQEAEIHYKNKVAEESE-KLALVNTQ------LNKLTQNVSKSAEMEKKVQDLEQ 397 ++ + +E++I + E +E KL+ N Q L + Q AE+E + LEQ Sbjct: 309 TVETEREESKILLEKMELEVAERKLSFHNLQEEMHHLLEQFEQAGQAQAELESRYSALEQ 368 Query: 398 KLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKE--QDLSQ--APSTASVNPAQQQLR 565 K + + + + + + D+L QN + QD ++ S ++ + QL+ Sbjct: 369 KHKAEMEEKTSHILSLQKTGQELQSACDALKDQNSKLLQDKNEQAVQSAQTIQQLEDQLQ 428 Query: 566 EPS 574 + S Sbjct: 429 QKS 431 Score = 31.2 bits (69), Expect = 2.7 Identities = 43/165 (26%), Positives = 65/165 (39%), Gaps = 36/165 (21%) Frame = +2 Query: 182 ADQLEVAQKHAA-ELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNK------- 337 A+QL V K + +VQ+ D+ LQE NK+ + T LNK Sbjct: 57 AEQLVVELKDIIRQKDVQLQQKDEALQEERKAADNKIKKLKLHAKAKLTSLNKYIEEMKA 116 Query: 338 ---------------LTQNVSKSAEMEKKVQDLEQKLQ--------LAYSKSDEQAKD-A 445 L+++ S E E +++ ++ KLQ L + QA+ A Sbjct: 117 QGGTVLPTEPQSEEQLSKHDKSSTEEEMEIEKIKHKLQEKEELISTLQAQLTQAQAEQPA 176 Query: 446 VVSTRSREFSLDSLTPQNKEQDLS----QAPSTASVNPAQQQLRE 568 ST EF + Q KE+ +S Q T + AQQ +RE Sbjct: 177 QSSTEMEEFVMMKQQLQEKEEFISTLQAQLSQTQAEQAAQQVVRE 221
>LAMC_DROME (Q03427) Lamin-C (pG-IF)| Length = 621 Score = 37.0 bits (84), Expect = 0.050 Identities = 52/223 (23%), Positives = 98/223 (43%), Gaps = 25/223 (11%) Frame = +2 Query: 20 KMQEHAN-LVHEKDQLEQQLLEVRKELEAAYRTIANQEEQ-ASVRE--------IKWDAY 169 K ++ A L E ++L +QL ++RK+LEA + E Q S+RE + Sbjct: 172 KFEDQAKELALENERLRRQLDDLRKQLEAETLARVDLENQNQSLREELAFKDQVHTQELT 231 Query: 170 KTYSADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALV-NTQLNKLTQ 346 +T S Q+E+++ + L Q LQE Y+ ++ E++ L+ + ++ L Sbjct: 232 ETRSRRQIEISEIDGRLSRQYEAKLQQSLQELRDQYEGQMRINREEIELLYDNEIQNLKA 291 Query: 347 NVSKSAE-----------MEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFS--LDSL 487 +++A+ M K+ L KLQ + + +A ++ R RE LD+ Sbjct: 292 AANRAAQGSALATEEVRLMRTKIDGLNAKLQ------NLEDTNAGLNARIRELENLLDTE 345 Query: 488 TPQNKEQDLS-QAPSTASVNPAQQQLREPSGIMAFKFILGVAL 613 ++ + S +A + QL+E G+M K L + + Sbjct: 346 RQRHNQYIASLEAELQRMRDEMAHQLQEYQGLMDIKVSLDLEI 388
>HMW2_MYCPN (P75471) Cytadherence high molecular weight protein 2 (Cytadherence| accessory protein 2) Length = 1818 Score = 37.0 bits (84), Expect = 0.050 Identities = 33/137 (24%), Positives = 66/137 (48%), Gaps = 5/137 (3%) Frame = +2 Query: 2 NEALTSK---MQEH-ANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAY 169 N+ L K +Q+H NLVH K +L+Q+ + ++ I +E+ + + + Sbjct: 443 NQVLKEKHRQVQQHFQNLVHAKKKLDQKRHYLAEQKRIDEEQIFKLKEKIATE--RRELE 500 Query: 170 KTYSADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNK-LTQ 346 K Y + + QK E + ++QL++ + ++N++ E+ +L L K TQ Sbjct: 501 KLYLVKKQKQDQK-----ENDLLIFEKQLRQYQADFENEIEEKQNELFASQKSLQKSFTQ 555 Query: 347 NVSKSAEMEKKVQDLEQ 397 +K AE+ +K Q + + Sbjct: 556 LKNKEAELNQKAQKIAE 572
>MYS3_HYDAT (P39922) Myosin heavy chain, clone 203 (Fragment)| Length = 539 Score = 36.6 bits (83), Expect = 0.065 Identities = 33/166 (19%), Positives = 80/166 (48%), Gaps = 14/166 (8%) Frame = +2 Query: 113 TIANQEEQASVREIKWDAYKTYSADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVA 292 ++A E++ +E + +A K E +K EL + A ++L + +++ Sbjct: 44 SVARAEDEMRAKEEELEAAKEQLKKDAEAKKKMEEEL-TEAMAQKEKLYASLQAETDRLI 102 Query: 293 EESEKLALVNTQLNKLTQNVSKSAE-----------MEKKVQDLEQKLQLAYSKSDE-QA 436 +KL + T +KL +++++ E +E+K+Q+ E+K+ K++E Q+ Sbjct: 103 TIEDKLLNLQTVKDKLESSLNEALEKLDGEEHSVLVLEEKIQEAEEKIDELTEKTEELQS 162 Query: 437 KDAVVST--RSREFSLDSLTPQNKEQDLSQAPSTASVNPAQQQLRE 568 + + T ++R+ +D+L ++QD + + A ++L++ Sbjct: 163 NISRLETEKQNRDKQIDTLNEDIRKQDETISKMNAEKKHVDEELKD 208
>MASK_XENLA (Q9PTG8) CPEB-associated factor Maskin (Cytoplasmic polyadenylation| element-binding protein-associated factor Maskin) Length = 931 Score = 36.6 bits (83), Expect = 0.065 Identities = 29/143 (20%), Positives = 67/143 (46%), Gaps = 1/143 (0%) Frame = +2 Query: 14 TSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQL 193 T+K++ + ++ EK Q++ L + ++ + Q+E A + Y ++ Sbjct: 789 TAKLELN-KVLQEKQQVQVDLNSMETSFSELFKRLEKQKE----------ALEGYRKNE- 836 Query: 194 EVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEME 373 E +K + V++ +Q+ Q + H + K+ +E++A V ++ + + E Sbjct: 837 EALKKCVEDYLVRIKKEEQRYQALKAHAEEKLNRANEEIAHVRSKAKSEATRLQATLRKE 896 Query: 374 K-KVQDLEQKLQLAYSKSDEQAK 439 + K+Q LE+ L+ ++DE K Sbjct: 897 QMKIQSLERSLEQKSKENDELTK 919
>CCD46_MOUSE (Q5PR68) Coiled coil domain containing protein 46| Length = 954 Score = 36.6 bits (83), Expect = 0.065 Identities = 25/106 (23%), Positives = 53/106 (50%), Gaps = 5/106 (4%) Frame = +2 Query: 176 YSADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVS 355 +S ++L++ QKH AE++ + + +L+E +I YK K E E + + ++ L ++ Sbjct: 267 FSEEKLKLQQKHDAEVQKILERKNNELEELKILYKKKQTETEETIRKLEKKVQILIRDCQ 326 Query: 356 KSAE-MEKKVQDL----EQKLQLAYSKSDEQAKDAVVSTRSREFSL 478 E E ++ +L EQ + + +++ +AV +F L Sbjct: 327 VIRETKENQITELKKICEQSTESLNNDWEKKLHNAVAEMEKDKFEL 372
>SAS6_BRARE (Q7ZVT3) Spindle assembly abnormal protein 6 homolog| Length = 627 Score = 36.6 bits (83), Expect = 0.065 Identities = 35/185 (18%), Positives = 94/185 (50%) Frame = +2 Query: 29 EHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQK 208 E + + +L+QQ ++R+ELE+++ + Q+ Q V E+ + D+ + Sbjct: 221 EREKALETQSRLQQQNEQLRQELESSHHR-STQQLQTKVSEL--ETANRELIDKKYKSDS 277 Query: 209 HAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEMEKKVQD 388 +L+ ++++L+++ Q ++ + E S + + + L Q ++ A +E++++D Sbjct: 278 TIRDLKAKLTSLEEECQRSKQQVLSLRRENSALDSECHEKERLLNQLQTRVAVLEQEIKD 337 Query: 389 LEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQAPSTASVNPAQQQLRE 568 +Q + + K+ + +T+ ++ S++ ++K+ +S+ ST V ++L + Sbjct: 338 KDQLVL--------RTKEVLEATQQQKNSVEG-NAESKQLQISKLEST--VKSLSEELIK 386 Query: 569 PSGIM 583 +GI+ Sbjct: 387 ANGII 391
>RAD50_YEAST (P12753) DNA repair protein RAD50 (EC 3.6.-.-) (153 kDa protein)| Length = 1312 Score = 36.6 bits (83), Expect = 0.065 Identities = 35/143 (24%), Positives = 70/143 (48%), Gaps = 8/143 (5%) Frame = +2 Query: 38 NLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKW--DAYKTYSADQLEVAQKH 211 +L ++KD+ + L +V+ E R I + +Q +V +I D ++T + ++ K Sbjct: 922 SLKNKKDEAQSVLDKVKNE-----RDIQVRNKQKTVADINRLIDRFQTIYNEVVDFEAKG 976 Query: 212 AAELEVQVSALDQ------QLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEME 373 EL+ + L+ +L+E N+V EE KLA N + L QN+ + E++ Sbjct: 977 FDELQTTIKELELNKAQMLELKEQLDLKSNEVNEEKRKLADSNNEEKNLKQNL-ELIELK 1035 Query: 374 KKVQDLEQKLQLAYSKSDEQAKD 442 ++Q +E ++ ++ E +D Sbjct: 1036 SQLQHIESEISRLDVQNAEAERD 1058
>DMD_CANFA (O97592) Dystrophin| Length = 3680 Score = 36.6 bits (83), Expect = 0.065 Identities = 38/180 (21%), Positives = 77/180 (42%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSA 184 E S+ +E + +L +Q ++ +E+E + I QE +S+ + Y A Sbjct: 1347 ETFNSRWRELHEEAVRRQKLLEQSIQSAQEIEKSLHLI--QESLSSIDK----QLAAYIA 1400 Query: 185 DQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSA 364 D+++ AQ ++Q ++ E+ N+ E ++++ K Q+VS Sbjct: 1401 DKVDAAQMPQEAQKIQSDLTSHEISLEEMKKHNQGKETAQRVLSQIDVAQKKLQDVSMKF 1460 Query: 365 EMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQAPSTASVN 544 + +K + EQ+LQ + DE + L +L ++ EQ++ Q+ VN Sbjct: 1461 RLFQKPANFEQRLQESKMILDEV-----------KMHLPALETKSVEQEVVQSQLNHCVN 1509
>RAD50_METJA (Q58718) DNA double-strand break repair rad50 ATPase| Length = 1005 Score = 36.6 bits (83), Expect = 0.065 Identities = 32/145 (22%), Positives = 74/145 (51%), Gaps = 10/145 (6%) Frame = +2 Query: 29 EHANLVHEKDQLEQQL--LEVR-KELEAAYRTIANQEEQASVREI--KWDAYKTYSADQL 193 E+ L+ EK +E+ + LE R +L + I + + S++EI K + +++ Sbjct: 413 EYITLLQEKKSIEKNINDLETRINKLLEETKNIDIESIENSLKEIEEKKKVLENLQKEKI 472 Query: 194 EVAQKHAAELEVQVSALDQQLQEA-EIHYKNKVA----EESEKLALVNTQLNKLTQNVSK 358 E+ +K E+ ++ L + L E E+ K + +E++K+ L+N +L ++ Sbjct: 473 ELNKK-LGEINSEIKRLKKILDELKEVEGKCPLCKTPIDENKKMELINQHKTQLNNKYTE 531 Query: 359 SAEMEKKVQDLEQKLQLAYSKSDEQ 433 E+ KK++++E+ ++ + D++ Sbjct: 532 LEEINKKIREIEKDIEKLKKEIDKE 556
>MYSP_SCHJA (Q05870) Paramyosin (Antigen Sj97)| Length = 866 Score = 36.6 bits (83), Expect = 0.065 Identities = 34/156 (21%), Positives = 67/156 (42%), Gaps = 20/156 (12%) Frame = +2 Query: 2 NEALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTI----------ANQEEQASVRE 151 N+A + M+E+ NL LE L + R+ EAA + AN+ E+ Sbjct: 550 NKANANLMKENKNLAQRVKDLETFLDDERRLREAAENNLQITEHKRIQLANEVEELRSAM 609 Query: 152 IKWDAYKTYSADQLEVAQKHAAELEVQVSAL--DQQLQEAEIHYK--------NKVAEES 301 + + ++ +LE Q +EL +QV+ L D++ E +I N Sbjct: 610 ENLERLRKHAETELEETQSRVSELTIQVNTLSNDKRRLEGDIGVMQADMDDAINAKQAAE 669 Query: 302 EKLALVNTQLNKLTQNVSKSAEMEKKVQDLEQKLQL 409 ++ +N ++ +L + + E K + L ++L++ Sbjct: 670 DRATRLNNEVLRLADELRQEQENYKHAEALRKQLEI 705 Score = 32.3 bits (72), Expect = 1.2 Identities = 41/165 (24%), Positives = 81/165 (49%), Gaps = 23/165 (13%) Frame = +2 Query: 5 EALTSKMQEH----ANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASV----REIKW 160 EAL Q++ A L H K ++EQ+L E +ELE+ ++ E+ +V E+K+ Sbjct: 465 EALRDMDQKYQASQAALNHLKSEMEQRLRERDEELESLRKSTTRTIEELTVTITEMEVKY 524 Query: 161 DA--------YKTYSAD---QLEVAQKHAAELEVQVSALDQQLQEAE--IHYKNKVAEES 301 + Y++ AD QL+ K A L + L Q++++ E + + ++ E + Sbjct: 525 KSELSRLKKRYESSIADLEIQLDATNKANANLMKENKNLAQRVKDLETFLDDERRLREAA 584 Query: 302 EKLALVNTQL--NKLTQNVSKSAEMEKKVQDLEQKLQLAYSKSDE 430 E N Q+ +K Q ++ E+ +++LE+ + A ++ +E Sbjct: 585 EN----NLQITEHKRIQLANEVEELRSAMENLERLRKHAETELEE 625
>MUKB_VIBCH (Q9KRC8) Chromosome partition protein mukB (Structural maintenance of| chromosome-related protein) Length = 1491 Score = 36.6 bits (83), Expect = 0.065 Identities = 37/147 (25%), Positives = 64/147 (43%), Gaps = 6/147 (4%) Frame = +2 Query: 47 HEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKHAAELE 226 HE ++ QQL E + + A RTI+ E+ A+V + + + Q + A + +L+ Sbjct: 897 HELEEKLQQLSEAKAFIAAHGRTISELEKVAAVLDADPEQFDALE-QQYQQADQALQQLK 955 Query: 227 VQVSALDQQLQEA-EIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEMEKKVQDLEQKL 403 Q+ AL L+ Y + V ++ L KL Q S+ ++++ + +L Sbjct: 956 AQIFALSDLLERRHHFAYSDSVDLLNQSSELSEQLKAKLVQAESERTRSREELKQAQAQL 1015 Query: 404 Q-----LAYSKSDEQAKDAVVSTRSRE 469 LA KS QAK V +E Sbjct: 1016 SQYNQLLASLKSSHQAKLETVQEFKQE 1042
>PIBF1_HUMAN (Q8WXW3) Progesterone-induced-blocking factor 1| Length = 757 Score = 36.6 bits (83), Expect = 0.065 Identities = 31/155 (20%), Positives = 70/155 (45%), Gaps = 5/155 (3%) Frame = +2 Query: 20 KMQEHANLVHEKDQLEQQLLEVRKE---LEAAYRTIANQEEQASVREIKWDAYKTYSADQ 190 + + + + E+D LEQ+++E+R++ LEA++ + + S + + T Sbjct: 260 RQENYDKVKSERDALEQEVIELRRKHEILEASHMIQTKERSELSKEVVTLEQTVTLLQKD 319 Query: 191 LEVAQKHAAELEVQVSALDQQLQ--EAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSA 364 E + EL V+ + + +L+ +A++ K EE + + + K Sbjct: 320 KEYLNRQNMELSVRCAHEEDRLERLQAQLEESKKAREEMYEKYVASRDHYK--------T 371 Query: 365 EMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSRE 469 E E K+ D ++++L ++ +Q ++A RE Sbjct: 372 EYENKLHDELEQIRLKTNQEIDQLRNASREMYERE 406 Score = 33.9 bits (76), Expect = 0.42 Identities = 40/174 (22%), Positives = 81/174 (46%), Gaps = 13/174 (7%) Frame = +2 Query: 29 EHANLVHEKDQLEQQLLEVRKELEAAYRTIAN--QEEQASVREIKWDAYKTYSADQLEVA 202 E+ N +H D+LEQ L+ +E++ + E ++RE + +A ++ +A Sbjct: 372 EYENKLH--DELEQIRLKTNQEIDQLRNASREMYERENRNLREARDNAVA--EKERAVMA 427 Query: 203 QKHAAELEVQVSALDQQLQEAEIHYKNKVAE----------ESEKLALVNTQLNK-LTQN 349 +K A E Q+ LD+ +E ++ ++KV E ESE++ L+ + + LTQ Sbjct: 428 EKDALEKHDQL--LDRY-RELQLSTESKVTEFLHQSKLKSFESERVQLLQEETARNLTQC 484 Query: 350 VSKSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQD 511 + + +KK++ L ++ + S+++ + + LD KE D Sbjct: 485 QLECEKYQKKLEVLTKEFYSLQASSEKRITELQAQNSEHQARLDIYEKLEKELD 538
>MYH8_RAT (P04462) Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal)| (MyHC-perinatal) (Fragment) Length = 257 Score = 36.6 bits (83), Expect = 0.065 Identities = 44/212 (20%), Positives = 88/212 (41%), Gaps = 32/212 (15%) Frame = +2 Query: 29 EHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQK 208 ++A+L++ K +LE + +++ E+E + N EE+A ++ DA A++L+ Q Sbjct: 42 QNASLINAKKKLENDVSQLQSEVEEVIQRARNAEEKA--KKAITDA--AMMAEELKKEQD 97 Query: 209 HAAELE-----------------------------VQVSALDQQLQEAEIHYKNKV---A 292 +A LE Q+ L+ +++E E +N+ A Sbjct: 98 TSAHLERMKKNMEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNA 157 Query: 293 EESEKLALVNTQLNKLTQNVSKSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREF 472 E + L ++ +LT + + ++QDL KLQ QA++A + Sbjct: 158 EAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLA 217 Query: 473 SLDSLTPQNKEQDLSQAPSTASVNPAQQQLRE 568 L + +E + + + VN + + RE Sbjct: 218 KFRKLQHELEEAEERADIAESQVNKLRVKSRE 249
>EP15_MOUSE (P42567) Epidermal growth factor receptor substrate 15 (Protein| Eps15) (AF-1p protein) Length = 897 Score = 36.6 bits (83), Expect = 0.065 Identities = 29/115 (25%), Positives = 57/115 (49%), Gaps = 6/115 (5%) Frame = +2 Query: 41 LVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYK---TYSADQLEVAQKH 211 L +K QLE+QL EVRK+ + I++ + + + +E + +Y+ + ++L Q+ Sbjct: 401 LDEQKAQLEEQLQEVRKKCAEEAQLISSLKAEITSQESQISSYEEELLKAREELSRLQQE 460 Query: 212 AAELEVQVSALDQQLQEAEIHYKNKVAEESE---KLALVNTQLNKLTQNVSKSAE 367 A+LE V + QL+ + H + E S +L + + + + N S S + Sbjct: 461 TAQLEESVESGKAQLEPLQQHLQESQQEISSMQMRLEMKDLETDNNQSNWSSSPQ 515
>MYSP_TAESO (P35418) Paramyosin (Antigen B) (AgB)| Length = 863 Score = 36.2 bits (82), Expect = 0.085 Identities = 44/168 (26%), Positives = 74/168 (44%), Gaps = 18/168 (10%) Frame = +2 Query: 41 LVHEKDQLEQQLLEVRKELE----AAYRTIANQEEQASVREIKWDA-----YKTYSAD-- 187 L H K ++EQ+L E +ELE + RTI S E+++ + K Y A Sbjct: 477 LNHLKSEMEQRLREKDEELENLRKSTTRTIEELTTTISEMEVRFKSDMSRLKKKYEATIS 536 Query: 188 ----QLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVS 355 QL+VA K L + L Q++QE + A E E+ A + N L + Sbjct: 537 ELEVQLDVANKANVNLNRENKTLAQRVQELQ------AALEDERRAREAAESN-LQVSER 589 Query: 356 KSAEMEKKVQDLEQKLQL---AYSKSDEQAKDAVVSTRSREFSLDSLT 490 K + +V+++ +L+L A ++ + DA S+++LT Sbjct: 590 KRIALASEVEEIRSQLELSDRARKNAESELNDANGRISELTLSVNTLT 637
>AMOT_HUMAN (Q4VCS5) Angiomotin| Length = 1084 Score = 36.2 bits (82), Expect = 0.085 Identities = 42/195 (21%), Positives = 83/195 (42%), Gaps = 15/195 (7%) Frame = +2 Query: 20 KMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEV 199 + Q+H + H + Q +QQ + E +A Q AS + + D + S Q V Sbjct: 381 QQQQHHHHHHHQQQQQQQPQQQPGEAYSAMPRA--QPSSASYQPVPADPFAIVSRAQQMV 438 Query: 200 A------QKHAAELE------VQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLT 343 + ELE ++ ++ ++Q Y+N V S++ AL NKL Sbjct: 439 EILSDENRNLRQELEGCYEKVARLQKVETEIQRVSEAYENLVKSSSKREALEKAMRNKLE 498 Query: 344 QNVSKSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTR---SREFSLDSLTPQNKEQDL 514 + + + + DL ++L+ A + E+ + TR S+ F+ + + + KE+ Sbjct: 499 GEIRRMHDFNR---DLRERLETANKQLAEKEYEGSEDTRKTISQLFAKNKESQREKEKLE 555 Query: 515 SQAPSTASVNPAQQQ 559 ++ + S N Q++ Sbjct: 556 AELATARSTNEDQRR 570
>M24_STRPY (P12379) M protein, serotype 24 precursor| Length = 539 Score = 36.2 bits (82), Expect = 0.085 Identities = 33/132 (25%), Positives = 67/132 (50%), Gaps = 9/132 (6%) Frame = +2 Query: 185 DQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEE-----SEKLALVNTQLNK---- 337 D LE Q+ A + E++ + L +L+ +++ + NK ++ +E+L+ +L K Sbjct: 50 DTLEKVQERADKFEIENNTL--KLKNSDLSFNNKALKDHNDELTEELSNAKEKLRKNDKS 107 Query: 338 LTQNVSKSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLS 517 L++ SK E+E + DLE+ L+ A + S A A + T E + + + E+ L Sbjct: 108 LSEKASKIQELEARKADLEKALEGAMNFS--TADSAKIKTLEAEKAALAARKADLEKALE 165 Query: 518 QAPSTASVNPAQ 553 A + ++ + A+ Sbjct: 166 GAMNFSTADSAK 177
>MY18A_HUMAN (Q92614) Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain)| (Molecule associated with JAK3 N-terminus) (MAJN) Length = 2054 Score = 36.2 bits (82), Expect = 0.085 Identities = 31/135 (22%), Positives = 65/135 (48%), Gaps = 9/135 (6%) Frame = +2 Query: 59 QLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKHAAELE---- 226 +L +L + + LE + + N E + R + + + Q E Q+ + E Sbjct: 1434 RLTAELQDTKLHLEG--QQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDML 1491 Query: 227 -VQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKS----AEMEKKVQDL 391 + +L QQL+E ++ +A ++K+ + +L ++ SK A+++K+++DL Sbjct: 1492 LAEAFSLKQQLEEKDMD----IAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDL 1547 Query: 392 EQKLQLAYSKSDEQA 436 E K++ + DEQA Sbjct: 1548 EAKVKDQEEELDEQA 1562 Score = 32.0 bits (71), Expect = 1.6 Identities = 40/199 (20%), Positives = 89/199 (44%), Gaps = 22/199 (11%) Frame = +2 Query: 5 EALTSKMQEHAN-LVHEKDQ--------------LEQQLLEVRKELEAAYRTIANQEEQA 139 E+L S+++E+ L E+DQ L++QL + ++E+ +A +E +A Sbjct: 1842 ESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGE----LARKEAEA 1897 Query: 140 SVR--EIKWDAYKTYSADQ-----LEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEE 298 S + E++ D +A+Q L++A K +L+ +A++ +++ E ++ + Sbjct: 1898 SRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQ---AAIEDEMESDE--NEDLINSL 1952 Query: 299 SEKLALVNTQLNKLTQNVSKSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSL 478 + + + NKL + +E+E +V ++ L S + D + + S Sbjct: 1953 QDMVTKYQKRKNKLEGDSDVDSELEDRVDGVKSWLSKNKGPSKAASDDGSLKSSSPTSYW 2012 Query: 479 DSLTPQNKEQDLSQAPSTA 535 SL P + + +T+ Sbjct: 2013 KSLAPDRSDDEHDPLDNTS 2031 Score = 30.8 bits (68), Expect = 3.6 Identities = 38/196 (19%), Positives = 84/196 (42%), Gaps = 8/196 (4%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEE----QASVREIKWDAYK 172 + + S E ++ ++ + E L +V+K+L + +QEE QA ++ A Sbjct: 1514 QKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKL 1573 Query: 173 TYSADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNV 352 + + Q H+ E+E + D++++EA + K+ + +L K+ + Sbjct: 1574 RLEMEMERMRQTHSKEME----SRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKV---L 1626 Query: 353 SKSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRS----REFSLDSLTPQNKEQDLSQ 520 + E+E K+ L ++ +S+++ + + T++ + LD L + Sbjct: 1627 REKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLK--------NS 1678 Query: 521 APSTASVNPAQQQLRE 568 APS + + QL E Sbjct: 1679 APSKREIAQLKNQLEE 1694
>DMD_PIG (Q5GN48) Dystrophin| Length = 3674 Score = 36.2 bits (82), Expect = 0.085 Identities = 42/183 (22%), Positives = 84/183 (45%), Gaps = 3/183 (1%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSA 184 E S+ +E + +L +Q ++ +E+E + I Q+ +S+ Y A Sbjct: 1341 ETFNSRWRELHEEAVRRQKLLEQSIQSAQEIEKSLHLI--QDSLSSIDH----QLAVYIA 1394 Query: 185 DQLEVAQ--KHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQL-NKLTQNVS 355 D+++ AQ + A +++ +++ + L+E + HY+ K E+ L +L K Q+VS Sbjct: 1395 DKVDAAQMPQEAQKIQSDLTSHEISLEEMKKHYQGK---EAAPRVLSQIELAQKKLQDVS 1451 Query: 356 KSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQAPSTA 535 + +K + EQ+LQ + DE + L +L ++ EQ++ Q+ Sbjct: 1452 MKFRLFQKPANFEQRLQESKMILDEV-----------KMHLPALEIKSVEQEVVQSQLNH 1500 Query: 536 SVN 544 VN Sbjct: 1501 CVN 1503
>MYO4_CAEEL (P02566) Myosin-4 (Myosin heavy chain B) (MHC B) (Uncoordinated| protein 54) Length = 1966 Score = 36.2 bits (82), Expect = 0.085 Identities = 35/152 (23%), Positives = 71/152 (46%), Gaps = 3/152 (1%) Frame = +2 Query: 35 ANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKHA 214 ++L K +LE ++ + +L+ N+ + A R K A T A++L Q+H+ Sbjct: 1733 SSLTSAKRKLEGEIQAIHADLDETL----NEYKAAEERSKKAIADATRLAEELRQEQEHS 1788 Query: 215 AELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEMEKKVQDLE 394 ++ L+QQL+E ++ +E+E AL + A++E++V++LE Sbjct: 1789 QHVDRLRKGLEQQLKEIQVR-----LDEAEAAALKGGK--------KVIAKLEQRVRELE 1835 Query: 395 QKL---QLAYSKSDEQAKDAVVSTRSREFSLD 481 +L Q + +++ A R +F +D Sbjct: 1836 SELDGEQRRFQDANKNLGRADRRVRELQFQVD 1867 Score = 33.9 bits (76), Expect = 0.42 Identities = 41/179 (22%), Positives = 78/179 (43%), Gaps = 17/179 (9%) Frame = +2 Query: 32 HANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKH 211 H N V K +LEQ L ++ LE R A+ ++Q K +L++AQ++ Sbjct: 1031 HQNKV--KAKLEQTLDDLEDSLEREKRARADLDKQ-----------KRKVEGELKIAQEN 1077 Query: 212 AAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEMEKKVQ-- 385 E Q L+ L++ E + + ++ ALV+ ++ S+ +E+E++++ Sbjct: 1078 IDESGRQRHDLENNLKKKESELHSVSSRLEDEQALVSKLQRQIKDGQSRISELEEELENE 1137 Query: 386 ------------DLEQKLQLAYSKSDEQ---AKDAVVSTRSREFSLDSLTPQNKEQDLS 517 DL+++L+ K DEQ V + RE L L +E +++ Sbjct: 1138 RQSRSKADRAKSDLQRELEELGEKLDEQGGATAAQVEVNKKREAELAKLRRDLEEANMN 1196 Score = 32.0 bits (71), Expect = 1.6 Identities = 46/210 (21%), Positives = 83/210 (39%), Gaps = 20/210 (9%) Frame = +2 Query: 26 QEHANLVHE-KDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVA 202 QEH+ V + LEQQL E++ L+ A A L+ Sbjct: 1785 QEHSQHVDRLRKGLEQQLKEIQVRLDEA------------------------EAAALKGG 1820 Query: 203 QKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEMEKKV 382 +K A+LE +V L+ +L + ++ + ++ L + ++ +L V + + +++ Sbjct: 1821 KKVIAKLEQRVRELESELDGEQRRFQ----DANKNLGRADRRVRELQFQVDEDKKNFERL 1876 Query: 383 QDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQD-------------LSQA 523 QDL KLQ +Q ++A LT Q ++ + S++ Sbjct: 1877 QDLIDKLQQKLKTQKKQVEEAEELANLNLQKYKQLTHQLEDAEERADQAENSLSKMRSKS 1936 Query: 524 PSTASVNPAQQQ------LREPSGIMAFKF 595 ++ASV P Q +R PS A F Sbjct: 1937 RASASVAPGLQSSASAAVIRSPSRARASDF 1966
>MAD1_SCHPO (P87169) Spindle assembly checkpoint component mad1 (Mitotic arrest| deficient protein 1) Length = 689 Score = 36.2 bits (82), Expect = 0.085 Identities = 38/137 (27%), Positives = 63/137 (45%) Frame = +2 Query: 2 NEALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYS 181 +E L +K +E A L + ++ +Q L E E+ ++NQ Q +++ + Sbjct: 136 HELLDAKWKEIAELKTQIEKNDQALSEKNHEV-----MVSNQALQ--MKDTNLTNLEKLF 188 Query: 182 ADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKS 361 AD E + EL +A +QQLQE +H N QL + + VS S Sbjct: 189 ADSREQLETKCKEL----AAAEQQLQELSVH---------------NQQLEESIKQVSSS 229 Query: 362 AEMEKKVQDLEQKLQLA 412 E+EK + EQ+LQ++ Sbjct: 230 IELEK--INAEQRLQIS 244
>INVO_HYLLA (P17941) Involucrin| Length = 522 Score = 36.2 bits (82), Expect = 0.085 Identities = 41/135 (30%), Positives = 65/135 (48%), Gaps = 12/135 (8%) Frame = +2 Query: 38 NLVHEKDQL---EQQL--LEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSAD--QLE 196 +L H+K +L E+Q+ L+ ++ E + + QE+Q + E + K QLE Sbjct: 225 HLEHQKGELQVPEEQVGQLKYLEQQEGQLKHLDQQEKQPELPEQQVGQLKHLEQQEGQLE 284 Query: 197 VAQKHAAEL---EVQVSALDQQLQEAEIHYKNKVAEESEKLALVNT--QLNKLTQNVSKS 361 + +L E QV L +QL+E E K+ EE + LV QL L Q + Sbjct: 285 HMEHQEGQLGLPEQQVGQL-KQLEEQEGQPKHLEEEEGQLKHLVQQEGQLEHLVQQERQL 343 Query: 362 AEMEKKVQDLEQKLQ 406 + E KVQ LEQ+++ Sbjct: 344 EQQEGKVQHLEQQVE 358 Score = 35.4 bits (80), Expect = 0.14 Identities = 45/189 (23%), Positives = 77/189 (40%), Gaps = 13/189 (6%) Frame = +2 Query: 44 VHEKDQLEQQLLEVR--KELEAAYRTIANQEEQAS-----VREIKWDAYKTYSADQLEVA 202 V + QLE+Q + + +E E + + QE Q R+++ K +Q Sbjct: 300 VGQLKQLEEQEGQPKHLEEEEGQLKHLVQQEGQLEHLVQQERQLEQQEGKVQHLEQQVEQ 359 Query: 203 QKHAAELEVQVSALDQQ-----LQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAE 367 KH E E Q+ L+QQ + E ++ + +E ++L L Q +L + A+ Sbjct: 360 LKHLEEQEGQLKHLEQQQGQLEVSEQQVGQPKHLEQEGKQLELPEQQEGQLKHLEKQEAQ 419 Query: 368 MEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKE-QDLSQAPSTASVN 544 +E Q Q+ K EQ + + +E L L Q + +DL Q + Sbjct: 420 LELPEQ------QVGQPKHPEQQEKQLEHPEQQEGQLKHLEQQEGQLKDLEQ--QKGQLE 471 Query: 545 PAQQQLREP 571 Q QL +P Sbjct: 472 QQQGQLEQP 480 Score = 32.0 bits (71), Expect = 1.6 Identities = 39/180 (21%), Positives = 77/180 (42%), Gaps = 13/180 (7%) Frame = +2 Query: 26 QEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVRE--------IKWDAYKTYS 181 Q+ + H + Q+EQ L+ +E E + + Q+ Q V E ++ + + Sbjct: 345 QQEGKVQHLEQQVEQ--LKHLEEQEGQLKHLEQQQGQLEVSEQQVGQPKHLEQEGKQLEL 402 Query: 182 ADQLEVAQKHAAELEVQVSALDQQL-QEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSK 358 +Q E KH + E Q+ +QQ+ Q + K E E+ QL L Q + Sbjct: 403 PEQQEGQLKHLEKQEAQLELPEQQVGQPKHPEQQEKQLEHPEQ---QEGQLKHLEQQEGQ 459 Query: 359 SAEMEKKVQDLEQKL----QLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQAP 526 ++E++ LEQ+ Q ++ + Q +D ++ +L + Q ++Q++ P Sbjct: 460 LKDLEQQKGQLEQQQGQLEQPVFAPAPGQVQDIQPVLPTKGEALLPVEQQQQKQEVQWPP 519
>HMW2_MYCGE (P47460) Cytadherence high molecular weight protein 2 (Cytadherence| accessory protein 2) Length = 1805 Score = 36.2 bits (82), Expect = 0.085 Identities = 36/162 (22%), Positives = 75/162 (46%), Gaps = 7/162 (4%) Frame = +2 Query: 50 EKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKHAAELEV 229 E D ++Q+L + + L + + + + + DA + DQL ++ +++ Sbjct: 805 EVDAIKQRLSDKHQALNMQQAELDRKTHELNNAFLNHDADQKSLQDQLATVKETQKLIDL 864 Query: 230 QVSA-LDQQLQEAE------IHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEMEKKVQD 388 + SA L++Q + AE H+ NK ++ + L Q ++ TQ K E++ D Sbjct: 865 ERSALLEKQREFAENVAGFKRHWSNKTSQLQKIYELTKKQESEQTQ---KETELKIAFSD 921 Query: 389 LEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDL 514 L++ Q+ + D++ + + + RE LD L +N + L Sbjct: 922 LQKDYQVFELQKDQEFRQ--IEAKQRE--LDKLAEKNNQVKL 959 Score = 33.9 bits (76), Expect = 0.42 Identities = 37/178 (20%), Positives = 71/178 (39%), Gaps = 4/178 (2%) Frame = +2 Query: 41 LVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKHAAE 220 L +E DQLE Q + E E YR + + + + + Y+ + DQ ++ KH + Sbjct: 200 LYNELDQLENQKRLLSIEYENTYRELVSADNELQ------NVYE--NIDQNQIQFKHQYQ 251 Query: 221 LEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEMEKKVQDLEQK 400 Y++++++ K+ L +L V K + + K+ D + Sbjct: 252 T-----------------YRDELSQLERKIQLTKQEL------VDKESALRVKIDDADFY 288 Query: 401 LQLAYSKSDEQAKDAV----VSTRSREFSLDSLTPQNKEQDLSQAPSTASVNPAQQQL 562 + ++ D+ AK ++ ++ + D L NKE+D A N Q L Sbjct: 289 INARLAELDDVAKQLSFQDGITKQNAQHVEDKLVALNKEKDRLNTQKEAFFNLRQSAL 346 Score = 31.6 bits (70), Expect = 2.1 Identities = 24/153 (15%), Positives = 65/153 (42%) Frame = +2 Query: 65 EQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKHAAELEVQVSAL 244 ++QLL+ ++ ++ R + E + + + DQ+ +K + + A Sbjct: 1293 KKQLLKAQRIVDDKNRLLKENERNLHFLSNETERKRAVLEDQISYFEKQRKQATDAILAS 1352 Query: 245 DQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEMEKKVQDLEQKLQLAYSKS 424 +++++ E + + E + +N K ++ + K+ +L++ LQ + + Sbjct: 1353 HKEVKKKEGELQKLLVELETRKTKLNNDFAKFSRQREEFENQRLKLLELQKTLQTQTNSN 1412 Query: 425 DEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQA 523 + + K S + ++ L Q KE D +++ Sbjct: 1413 NFKTKAIQEIENSYKRGMEELNFQKKEFDKNKS 1445
>ASPP2_HUMAN (Q13625) Apoptosis-stimulating of p53 protein 2 (Tumor suppressor| p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen) Length = 1128 Score = 36.2 bits (82), Expect = 0.085 Identities = 42/206 (20%), Positives = 93/206 (45%), Gaps = 12/206 (5%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSA 184 + L + ++ + ++DQ +QQ + +++L+ NQE A +++++ A K + Sbjct: 146 QQLLATKEQRLKFLKQQDQRQQQQVAEQEKLKRLKEIAENQE--AKLKKVR--ALKGH-V 200 Query: 185 DQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALV-NTQLNKLTQNVSKS 361 +Q ++ E Q++ L QQ Q + +KV E + +L ++ N +++ N S Sbjct: 201 EQKRLSNGKLVEEIEQMNNLFQQKQRELVLAVSKVEELTRQLEMLKNGRIDSHHDNQSAV 260 Query: 362 AEMEKKVQDLE--QKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKE---------Q 508 AE+++ ++L+ KL + +Q ++ + S +D + ++ Q Sbjct: 261 AELDRLYKELQLRNKLNQEQNAKLQQQRECLNKRNSEVAVMDKRVNELRDRLWKKKAALQ 320 Query: 509 DLSQAPSTASVNPAQQQLREPSGIMA 586 P ++ N QQ PS + A Sbjct: 321 QKENLPVSSDGNLPQQAASAPSRVAA 346
>GCC1_HUMAN (Q96CN9) GRIP and coiled-coil domain-containing protein 1 (Golgi| coiled coil protein 1) Length = 775 Score = 36.2 bits (82), Expect = 0.085 Identities = 36/176 (20%), Positives = 78/176 (44%), Gaps = 22/176 (12%) Frame = +2 Query: 20 KMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEV 199 + +HA ++ E +L Q+ R++LE + +E + ++ A + Y+A+Q+E Sbjct: 239 EQSDHALMLRELQKLLQEERTQRQDLE-----LRLEETREAL------AGRAYAAEQMEG 287 Query: 200 AQKHAAELEVQVSALDQQLQ---------------------EAEIHYKNKVAEESEKLAL 316 + +L +V L +LQ + H++ ++ +E K AL Sbjct: 288 FELQTKQLTREVEELKSELQAIRDEKNQPDPRLQELQEEAARLKSHFQAQLQQEMRKTAL 347 Query: 317 VNTQLNKLTQ-NVSKSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLD 481 QL + +Q + A +E ++ ++ + L Y K+ ++ + A+ + R LD Sbjct: 348 AEDQLRQQSQVEEQRVAALENQISEVSELLG-TYEKAKQKDQLAIQKLKERILQLD 402
>MY18A_MOUSE (Q9JMH9) Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain)| (Molecule associated with JAK3 N-terminus) (MAJN) Length = 2035 Score = 36.2 bits (82), Expect = 0.085 Identities = 30/135 (22%), Positives = 65/135 (48%), Gaps = 9/135 (6%) Frame = +2 Query: 59 QLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKHAAELE---- 226 +L +L + + LE + + N E + R + + + Q E Q+ + E Sbjct: 1430 RLTAELQDTKLHLEG--QQVRNHELEKKQRRFDSELSQAHEETQREKLQREKLQREKDML 1487 Query: 227 -VQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKS----AEMEKKVQDL 391 + +L QQ++E ++ +A ++K+ + +L ++ SK A+++K+++DL Sbjct: 1488 LAEAFSLKQQMEEKDLD----IAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDL 1543 Query: 392 EQKLQLAYSKSDEQA 436 E K++ + DEQA Sbjct: 1544 EAKVKDQEEELDEQA 1558 Score = 31.2 bits (69), Expect = 2.7 Identities = 37/196 (18%), Positives = 84/196 (42%), Gaps = 8/196 (4%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEE----QASVREIKWDAYK 172 + + S E ++ ++ + E L +V+K+L + +QEE QA ++ A Sbjct: 1510 QKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGSIQMLEQAKL 1569 Query: 173 TYSADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNV 352 + + Q H+ E+E + D++++EA + K+ + +L + + + Sbjct: 1570 RLEMEMERMRQTHSKEME----SRDEEVEEARQSCQKKLKQMEVQL---EEEYEDKQKAL 1622 Query: 353 SKSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRS----REFSLDSLTPQNKEQDLSQ 520 + E+E K+ L ++ +S+++ + + T++ + LD L + Sbjct: 1623 REKRELESKLSTLSDQVNQRDFESEKRLRKDLKRTKALLADAQIMLDHLK--------NN 1674 Query: 521 APSTASVNPAQQQLRE 568 APS + + QL E Sbjct: 1675 APSKREIAQLKNQLEE 1690
>INVO_MOUSE (P48997) Involucrin| Length = 467 Score = 36.2 bits (82), Expect = 0.085 Identities = 21/92 (22%), Positives = 44/92 (47%), Gaps = 1/92 (1%) Frame = +2 Query: 224 EVQVSALDQQLQEAEIHY-KNKVAEESEKLALVNTQLNKLTQNVSKSAEMEKKVQDLEQK 400 ++QV Q+LQE E+H K ++ +E + L + Q + Q + +++ Q +Q+ Sbjct: 85 QLQVKKSQQELQEQELHLEKQQLPQEPQGLLCLEQQQQQEPQMQEQHLRQQQQQQQQQQQ 144 Query: 401 LQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQ 496 Q + + Q + + + ++ D L PQ Sbjct: 145 QQQQQQQQETQEQGLCLGQKQQQQQQDMLVPQ 176
>INVO_CEBAL (P24709) Involucrin| Length = 428 Score = 36.2 bits (82), Expect = 0.085 Identities = 44/195 (22%), Positives = 79/195 (40%), Gaps = 14/195 (7%) Frame = +2 Query: 20 KMQEHANLVHEKDQLEQQL---------LEVRKELEAAYRTIANQEEQASVREIKWDAYK 172 ++ E + +QLE+QL L+ +E E + + QEEQ ++ ++ + Sbjct: 214 ELPEQVDQPKHLEQLEKQLEHPEQQEGKLKKLEEEEEQLKHLEQQEEQ--LKHLEQQEGQ 271 Query: 173 TYSADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNV 352 +Q E KH + E Q+ L+Q QE ++ + +S+ L QL Q Sbjct: 272 LEHLEQQEGELKHLEQCEGQLEHLEQ--QEGQLELPEQQVGQSKHLEQEEKQLEHPEQQE 329 Query: 353 SKSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTP--QNKEQDLSQ-- 520 + + K+ LE Q+ K EQ + + +E + + +E+ L Q Sbjct: 330 GQLKHLGKQEAQLELPEQVGQPKHLEQQEKQLEHPEQQEEQQEGQLKDLEQQERQLEQPV 389 Query: 521 -APSTASVNPAQQQL 562 AP+ QQ L Sbjct: 390 FAPAPGQAQDIQQAL 404 Score = 34.3 bits (77), Expect = 0.32 Identities = 41/182 (22%), Positives = 78/182 (42%), Gaps = 12/182 (6%) Frame = +2 Query: 62 LEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKHAAELEVQVSA 241 LEQQ ++ K LE + + E+Q E+ + +QLE +H + E ++ Sbjct: 186 LEQQEGQL-KHLEEQKGQLKHLEQQEGQLELPEQVDQPKHLEQLEKQLEHPEQQEGKLKK 244 Query: 242 LDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEMEK---KVQDLEQ----- 397 L++ +E ++ + + E+ + L QL L Q + +E+ +++ LEQ Sbjct: 245 LEE--EEEQLKHLEQQEEQLKHLEQQEGQLEHLEQQEGELKHLEQCEGQLEHLEQQEGQL 302 Query: 398 ---KLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDL-SQAPSTASVNPAQQQLR 565 + Q+ SK EQ + + +E L L Q + +L Q + ++QL Sbjct: 303 ELPEQQVGQSKHLEQEEKQLEHPEQQEGQLKHLGKQEAQLELPEQVGQPKHLEQQEKQLE 362 Query: 566 EP 571 P Sbjct: 363 HP 364
>GOGA5_RAT (Q3ZU82) Golgin subfamily A member 5 (Golgin-84)| Length = 728 Score = 36.2 bits (82), Expect = 0.085 Identities = 35/153 (22%), Positives = 71/153 (46%), Gaps = 24/153 (15%) Frame = +2 Query: 80 EVRKELEAAYRTIANQEEQASVREIKW-----------DAYKTYSADQLEVAQKHAAELE 226 E+R +++ +A ++ Q +V +++ +A + +++ + Q H Sbjct: 280 ELRAQVDDLTEAVAAKDSQLAVLKVRLQEADQVLSSRTEALEALQSEKSRIMQDHNEGSS 339 Query: 227 VQVSALD--QQLQEAEIHYKNKVAEESEKLALVNTQLNKLT---QNVS--------KSAE 367 +Q AL Q+ EA+ K + + + T+LNK+ QN++ K +E Sbjct: 340 LQNQALQTLQERHEADATLKREQESYKQMQSEFATRLNKMEVERQNLAEAVTLAERKYSE 399 Query: 368 MEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSR 466 KKV DL+Q+++L + S E AK +V + + Sbjct: 400 ERKKVDDLQQQVKL-HRSSLESAKQELVDYKQK 431
>MD1L1_HUMAN (Q9Y6D9) Mitotic spindle assembly checkpoint protein MAD1 (Mitotic| arrest deficient-like protein 1) (MAD1-like 1) (Mitotic checkpoint MAD1 protein-homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181) Length = 718 Score = 36.2 bits (82), Expect = 0.085 Identities = 43/190 (22%), Positives = 90/190 (47%), Gaps = 2/190 (1%) Frame = +2 Query: 20 KMQEHANLVHEK--DQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQL 193 ++QE EK +QLE+ + ++ L+AA + + +E+ + +A K ++ Sbjct: 112 QLQEREAGAEEKMQEQLERNR-QCQQNLDAASKRLREKEDSLAQAGETINALK----GRI 166 Query: 194 EVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEME 373 Q + E++V L+ + QE + ++ + +K N ++ +L + A+ E Sbjct: 167 SELQWSVMDQEMRVKRLESEKQELQ----EQLDLQHKKCQEANQKIQELQASQEARADHE 222 Query: 374 KKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQAPSTASVNPAQ 553 ++++DLEQKL L EQ V + +S L L E++L Q ++ Sbjct: 223 QQIKDLEQKLSL-----QEQDAAIVKNMKSELVRLPRL-----ERELKQLREESA---HL 269 Query: 554 QQLREPSGIM 583 +++RE +G++ Sbjct: 270 REMRETNGLL 279
>ZYG12_CAEEL (Q23529) Zygote defective protein 12| Length = 774 Score = 35.8 bits (81), Expect = 0.11 Identities = 44/197 (22%), Positives = 81/197 (41%), Gaps = 14/197 (7%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQ---EEQASVREIKWDAYKT 175 E L ++ +H V E + + +L+E R LE NQ +E + R + ++ Sbjct: 440 EQLEIQLIQHKEKVKELEDRKDELIEERNRLE-------NQLIFKEAVTPRSLHESMFE- 491 Query: 176 YSADQLEVAQKHAAELEVQVSALDQQLQEAE-----------IHYKNKVAEESEKLALVN 322 A L +K+ LE++ L +++QE E + KN V EE + A Sbjct: 492 --AGNLSFDEKNTLPLEIENKRLTERIQELESLEPLKGELITLKSKNGVLEEEKLFA--- 546 Query: 323 TQLNKLTQNVSKSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNK 502 + E++++++DL++ L K+ E A VV + + + + Sbjct: 547 ---------TKQIEELQQQIEDLQENL----LKNQEHASGDVVGLK-----IQLEKAEVE 588 Query: 503 EQDLSQAPSTASVNPAQ 553 Q + +A A N AQ Sbjct: 589 AQQMREAKMRAETNQAQ 605
>PKHA6_MOUSE (Q7TQG1) Pleckstrin homology domain-containing family A member 6| (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3) Length = 1173 Score = 35.8 bits (81), Expect = 0.11 Identities = 30/134 (22%), Positives = 60/134 (44%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSA 184 + L K+ E +V E+++L QQL ++ LE+A + E + AY Sbjct: 605 DKLLGKLCEQNKVVREQERLVQQLRAEKESLESALMGTHQELEMFGSQP----AYPEKLL 660 Query: 185 DQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSA 364 + E Q + V++S L + + Y+N +E S + QLN QN + Sbjct: 661 HKKESLQNQLINIRVELSQATTALTNSTVVYENLESEVSALHDELWEQLNLDIQNEVLNR 720 Query: 365 EMEKKVQDLEQKLQ 406 +++K++ ++ ++ Sbjct: 721 QIQKEIWRIQDVME 734
>PHLB2_MOUSE (Q8K1N2) Pleckstrin homology-like domain family B member 2 (Protein| LL5-beta) Length = 1249 Score = 35.8 bits (81), Expect = 0.11 Identities = 34/126 (26%), Positives = 54/126 (42%), Gaps = 16/126 (12%) Frame = +2 Query: 38 NLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQA-----SVREIKWDAYKTYSADQLEVA 202 N+V EK + + +L R++LE + Q+ Q S+RE K AD L+V Sbjct: 656 NIVGEKTKEKVKLDAEREKLERLQELYSEQKTQLDNCPESMREQLQQQLKR-DADLLDVE 714 Query: 203 QKHAAELEVQV----SALD-------QQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQN 349 KH +LE Q S LD QQL Y+ + EK++ + Q + + Q Sbjct: 715 SKHFEDLEFQQLEHESRLDEEKENLTQQLLREVAEYQRNIVARKEKISALKKQASHIVQQ 774 Query: 350 VSKSAE 367 + + Sbjct: 775 AQREQD 780
>MYS2_DICDI (P08799) Myosin-2 heavy chain, non muscle (Myosin II heavy chain, non| muscle) Length = 2116 Score = 35.8 bits (81), Expect = 0.11 Identities = 42/157 (26%), Positives = 73/157 (46%), Gaps = 4/157 (2%) Frame = +2 Query: 8 ALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTI-ANQEEQASVREIKWDAYKTYSA 184 AL + ++ +LV E D++++QL + E+ A + + A + + + E++ Sbjct: 1665 ALNASEKKIKSLVAEVDEVKEQLED---EILAKDKLVKAKRALEVELEEVR--------- 1712 Query: 185 DQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSA 364 DQLE + +ELE L ++++ + Y +V E++ KL +L + K Sbjct: 1713 DQLEEEEDSRSELEDSKRRLTTEVEDIKKKYDAEV-EQNTKLDEAKKKLTDDVDTLKKQL 1771 Query: 365 EMEKKV--QDLEQKLQLAYSKSDEQAK-DAVVSTRSR 466 E EKK + K +L D AK DA V RSR Sbjct: 1772 EDEKKKLNESERAKKRLESENEDFLAKLDAEVKNRSR 1808
>MYH8_HUMAN (P13535) Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal)| (MyHC-perinatal) Length = 1937 Score = 35.8 bits (81), Expect = 0.11 Identities = 43/212 (20%), Positives = 88/212 (41%), Gaps = 32/212 (15%) Frame = +2 Query: 29 EHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQK 208 ++ +L++ K +LE + +++ E+E + N EE+A ++ DA A++L+ Q Sbjct: 1722 QNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKA--KKAITDA--AMMAEELKKEQD 1777 Query: 209 HAAELE-----------------------------VQVSALDQQLQEAEIHYKNKV---A 292 +A LE Q+ L+ +++E E +N+ A Sbjct: 1778 TSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNA 1837 Query: 293 EESEKLALVNTQLNKLTQNVSKSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREF 472 E + L ++ +LT + + ++QDL KLQ QA++A + + Sbjct: 1838 EAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLS 1897 Query: 473 SLDSLTPQNKEQDLSQAPSTASVNPAQQQLRE 568 L + +E + + + VN + + RE Sbjct: 1898 KFRKLQHELEEAEERADIAESQVNKLRVKSRE 1929 Score = 34.7 bits (78), Expect = 0.25 Identities = 42/180 (23%), Positives = 75/180 (41%), Gaps = 9/180 (5%) Frame = +2 Query: 47 HEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKHAAELE 226 H+ D L +Q E ++ R ++ + + K++ ++LE A+K A Sbjct: 1341 HDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLA--- 1397 Query: 227 VQVSALDQQLQEAEIHYK---NKVAEESEKLALVNTQLNKLTQNVSKS----AEMEKKVQ 385 Q+LQEAE H + K A + + ++ L +V +S A ++KK + Sbjct: 1398 -------QRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQR 1450 Query: 386 DLEQKLQLAYSKSDE-QAKDAVVSTRSREFSLDSLTPQN-KEQDLSQAPSTASVNPAQQQ 559 + ++ L K +E QA+ SR S + +N E+ L Q + N QQ Sbjct: 1451 NFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQ 1510
>KIF4A_MOUSE (P33174) Chromosome-associated kinesin KIF4A (Chromokinesin)| Length = 1231 Score = 35.8 bits (81), Expect = 0.11 Identities = 42/189 (22%), Positives = 83/189 (43%), Gaps = 1/189 (0%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSA 184 EAL KM ++ N + ++ Q + K LE+ ++ ++E+ V E++ A Sbjct: 538 EALAKKMTQNDN---QLQPIQFQYQDNIKNLESEVLSLQREKEEL-VLELQTAKKDANQA 593 Query: 185 DQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKL-TQNVSKS 361 E +K ELE Q++ L ++LQE K K + E ++ +N ++ + Q V Sbjct: 594 KLSERRRKRLQELEGQIADLKKKLQEQSKLLKLKESTE-HTVSKLNQEIRMMKNQRVQLM 652 Query: 362 AEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQAPSTASV 541 +M++ + Q Q + D++ R R++ L L ++Q T Sbjct: 653 RQMKEDAEKFRQWKQ----QKDKEVIQLKERDRKRQYELLKLERNFQKQSNVLRRKTEEA 708 Query: 542 NPAQQQLRE 568 A ++L++ Sbjct: 709 AAANKRLKD 717
>PUMA_PARUN (O61308) 227 kDa spindle- and centromere-associated protein (PUMA1)| Length = 1955 Score = 35.8 bits (81), Expect = 0.11 Identities = 38/154 (24%), Positives = 62/154 (40%), Gaps = 3/154 (1%) Frame = +2 Query: 50 EKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKHAAELEV 229 EKD L Q+L +V +LE T+ ++ Q S ++ +E + E E Sbjct: 628 EKDSLAQKLADVTHKLEI--ETVRREDIQRSC---------VGHSEDVEKQRLQIIEYER 676 Query: 230 QVSALDQQLQEAEIHYKN---KVAEESEKLALVNTQLNKLTQNVSKSAEMEKKVQDLEQK 400 +V AL + E + + K KV + V T++ KLT + K+Q +Q Sbjct: 677 EVMALRRLNDELDTNVKTGQAKVTSLENSIISVQTEVTKLTT-------LNDKLQKEKQS 729 Query: 401 LQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNK 502 + + K+D R E D L +NK Sbjct: 730 IMSSKQKADTDVDLLKEKLRKLEQECDKLKEENK 763 Score = 32.3 bits (72), Expect = 1.2 Identities = 44/189 (23%), Positives = 77/189 (40%), Gaps = 25/189 (13%) Frame = +2 Query: 20 KMQEHANLVHEKDQLEQQLLEVRK---ELEAAYRTI----ANQEEQASVREIKWDAYKTY 178 K+ + LV K+QL+ + E K EL A+R N Q R + D K+ Sbjct: 1206 KLDKEVQLV--KEQLQYKSDEFHKALDELANAHRISEEGRVNAIHQLEARRFEIDDLKSR 1263 Query: 179 ---SADQLEVAQKHAAELEVQVSALDQQLQEAEIHY-KNKVAEESEKLALVNTQLNKLTQ 346 S +L Q+ + + AL+ ++ + ++ VAEE ++ + TQ+ KL Sbjct: 1264 LENSEQRLATLQQEYVNADKERGALNDAMRRFQATISRSVVAEEHVDVSTIETQMQKLMS 1323 Query: 347 NVSKSAEMEKKVQD----LEQKLQLAYSKSDEQA------KDAVVST----RSREFSLDS 484 + + +D L+ + +YS D Q ++ V+S R E L S Sbjct: 1324 RIEAIERERNEYRDSLNRLKNRCSTSYSSVDRQETVYRTFEERVISAEDERRKVELKLSS 1383 Query: 485 LTPQNKEQD 511 + K Q+ Sbjct: 1384 MKEMLKSQE 1392
>ABRA_PLAFC (P22620) 101 kDa malaria antigen (p101) (Acidic basic repeat antigen)| Length = 743 Score = 35.8 bits (81), Expect = 0.11 Identities = 36/150 (24%), Positives = 72/150 (48%), Gaps = 6/150 (4%) Frame = +2 Query: 11 LTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEE-QASVREIKWDAYKTYSAD 187 L +K ++H ++ Q+ +++EL+A Y + N ++++I ++ + Sbjct: 590 LGNKDKKHIEAINNDIQI------IKQELQAIYNELMNYTNGNKNIQQI----FQQNILE 639 Query: 188 QLEVAQKHAAELEVQVSALDQQLQEAEIHY---KNKVAEESEKLALVNTQLNKLTQNVSK 358 + Q+ E+E QV A+ +Q+ EAE+ KNK EE EK + + + + Sbjct: 640 NDVLNQETEEEMEKQVEAITKQI-EAEVDALAPKNKEEEEKEKEKEKEKEEKEKEEKEKE 698 Query: 359 SAEMEK--KVQDLEQKLQLAYSKSDEQAKD 442 E EK K ++ E+K + K +EQ ++ Sbjct: 699 EKEKEKEEKEKEKEEKEEEKKEKEEEQEEE 728
>RAD50_SULTO (Q96YR5) DNA double-strand break repair rad50 ATPase| Length = 879 Score = 35.8 bits (81), Expect = 0.11 Identities = 38/141 (26%), Positives = 65/141 (46%), Gaps = 6/141 (4%) Frame = +2 Query: 2 NEALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYS 181 NE+ K+Q+ L + K +LE ++ KE + Y I E+ +E ++ Sbjct: 194 NESENQKIQKEKELENIKRELEDLNIKEEKERKK-YEDIVKLNEEEEKKEKRY----VEL 248 Query: 182 ADQLEVAQKHAAELEVQVSALDQQLQEAE-----IHYKNKVAEESEKLALVNTQLNKLTQ 346 L + +EL +V ++ +E E I K+K+ EE EK+ ++ KL Q Sbjct: 249 ISLLNKLKDDISELREEVKDENRLREEKEKLEKDILEKDKLIEEKEKIIEAQNKI-KLAQ 307 Query: 347 NVSKSAEMEK-KVQDLEQKLQ 406 KS + K + DLE+KL+ Sbjct: 308 EKEKSLKTIKINLTDLEEKLK 328
>SPRL1_HUMAN (Q14515) SPARC-like protein 1 precursor (High endothelial venule| protein) (Hevin) (MAST 9) Length = 664 Score = 35.8 bits (81), Expect = 0.11 Identities = 32/133 (24%), Positives = 58/133 (43%) Frame = +2 Query: 113 TIANQEEQASVREIKWDAYKTYSADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVA 292 T +NQ+E + RE + + YS QL + KH+ L DQ QE + + N Sbjct: 149 TDSNQQESITKREENQEQPRNYSHHQLNRSSKHSQGLR------DQGNQEQDPNISNGEE 202 Query: 293 EESEKLALVNTQLNKLTQNVSKSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREF 472 EE ++ V T N ++ + E + K + ++SD+ +++ T+ + Sbjct: 203 EEEKEPGEVG------THNDNQERKTELPREHANSKQEEDNTQSDDILEESDQPTQVSKM 256 Query: 473 SLDSLTPQNKEQD 511 D N+EQ+ Sbjct: 257 QEDEFDQGNQEQE 269
>Y1209_CAMJE (Q9PN86) UPF0144 protein Cj1209| Length = 517 Score = 35.4 bits (80), Expect = 0.14 Identities = 29/130 (22%), Positives = 58/130 (44%) Frame = +2 Query: 53 KDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKHAAELEVQ 232 K + E++ + +K+ + ++ +E++ E K K Y L +QKH L+ Sbjct: 67 KKKYEEKTHKFQKDFNQKFDDLSKKEQKLQQEEEKLKEDKEY----LCKSQKHIQNLQSD 122 Query: 233 VSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEMEKKVQDLEQKLQLA 412 V L KNK E+ + + + LTQN +K ++K ++ +++ Sbjct: 123 VDKL-----------KNKYQEKLDDVLKILEHSTGLTQNEAKEIILKKVEENSREQIAHI 171 Query: 413 YSKSDEQAKD 442 K +E+AK+ Sbjct: 172 VRKYEEEAKN 181
>TRIPB_HUMAN (Q15643) Thyroid receptor-interacting protein 11 (TRIP-11)| (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution related gene on chromosome 14) Length = 1979 Score = 35.4 bits (80), Expect = 0.14 Identities = 37/176 (21%), Positives = 81/176 (46%), Gaps = 24/176 (13%) Frame = +2 Query: 2 NEALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYS 181 NEA + L+ E+D+L+QQ+ ++ + + T+ N + +++ +++ + ++ + Sbjct: 1194 NEAGGVNSHQFEELLQERDKLKQQVKKMEEWKQQVMTTVQNMQHESA--QLQEELHQLQA 1251 Query: 182 ADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESE-----------------KL 310 Q+ V + ++L+V + L Q ++ E KN E ++ KL Sbjct: 1252 --QVLVDSDNNSKLQVDYTGLIQSYEQNETKLKNFGQELAQVQHSIGQLCNTKDLLLGKL 1309 Query: 311 ALVNTQLNKLTQNVSKSAE--MEKKVQDLEQKLQLAYSKSDE-----QAKDAVVST 457 +++ QL+ + +SAE K + L + +L + +E Q KDA + T Sbjct: 1310 DIISPQLSSASLLTPQSAECLRASKSEVLSESSELLQQELEELRKSLQEKDATIRT 1365 Score = 32.7 bits (73), Expect = 0.94 Identities = 35/166 (21%), Positives = 72/166 (43%), Gaps = 7/166 (4%) Frame = +2 Query: 50 EKDQLEQQLLEVRKEL-EAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQK---HAA 217 EK ++E +L +K L E A + EE ++ R + A + +++ QK A Sbjct: 717 EKGEIEAELCWAKKRLLEEANKYEKTIEELSNARNLNTSALQLEHEHLIKLNQKKDMEIA 776 Query: 218 ELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQ---LNKLTQNVSKSAEMEKKVQD 388 EL+ + +D +E + + + E+ + L+N + + KL + SK E K Sbjct: 777 ELKKNIEQMDTDHKETKDVLSSSLEEQKQLTQLINKKEIFIEKLKERSSKLQEELDKYSQ 836 Query: 389 LEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQAP 526 +K ++ +E+ + ++ S + L + +E+ AP Sbjct: 837 ALRKNEILRQTIEEKDR-SLGSMKEENNHLQEELERLREEQSRTAP 881 Score = 31.6 bits (70), Expect = 2.1 Identities = 34/166 (20%), Positives = 69/166 (41%), Gaps = 15/166 (9%) Frame = +2 Query: 89 KELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKHAAELEVQVSALDQQLQEAE 268 KE A+ + ++EQ E+ S + V + + +V ++ +Q++ Sbjct: 1504 KEKALAFEQLLKEKEQGKTGELNQLLNAVKSMQEKTVVFQQERD-QVMLALKQKQMENTA 1562 Query: 269 IHYKNKVAEESEKLALVNTQLNKLTQNVSKS---------------AEMEKKVQDLEQKL 403 + +N+V +K N +L +L ++ +S A++ KKV LE+KL Sbjct: 1563 L--QNEVQRLRDKEFRSNQELERLRNHLLESEDSYTREALAAEDREAKLRKKVTVLEEKL 1620 Query: 404 QLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQAPSTASV 541 + + + + A V S + L+ ++ Q E L + S V Sbjct: 1621 VSSSNAMENASHQASVQVESLQEQLNVVSKQRDETALQLSVSQEQV 1666
>IF2_IDILO (Q5QTY8) Translation initiation factor IF-2| Length = 896 Score = 35.4 bits (80), Expect = 0.14 Identities = 35/159 (22%), Positives = 63/159 (39%) Frame = +2 Query: 50 EKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKHAAELEV 229 EK++L ++ + R++ EA R EE+ + + K DA K + E +K E E Sbjct: 156 EKEKLRKEKEKERQKAEAEKRAAMTPEEREAADKAKADAEKLKRQQEEEARKKAEKEAEA 215 Query: 230 QVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEMEKKVQDLEQKLQL 409 Q AEE+ KLA N + E +K+ Q ++ + Sbjct: 216 Q-------------------AEEARKLAEENAK--------RWEEEEQKRKQQEKEDVHF 248 Query: 410 AYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQAP 526 S + ++A+DA R+ + K+++ P Sbjct: 249 TTSSTAQEAEDAQDFDEERKSRKRGKKRRRKDEESDDTP 287
>PEA2_YEAST (P40091) Protein PEA2 (Protein PPF2)| Length = 420 Score = 35.4 bits (80), Expect = 0.14 Identities = 33/121 (27%), Positives = 58/121 (47%), Gaps = 1/121 (0%) Frame = +2 Query: 179 SADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQL-NKLTQNVS 355 S+ +LE + ++L++ + L +Q + Y ++ EKL N +L +KL N S Sbjct: 241 SSKKLEELETAFSDLQLAHNFLTKQFENDRAEY----VQDIEKLTRTNRELQDKLLNNHS 296 Query: 356 KSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQAPSTA 535 ++ EKK+ +LEQ+ +K E+A + + S+R F + S D S S Sbjct: 297 NLSKTEKKLHELEQE-----NKELEKANNKLNSSR-HNFGMSSPASSPVTWDPSSPSSVG 350 Query: 536 S 538 S Sbjct: 351 S 351
>IF2_SHISS (Q3YX73) Translation initiation factor IF-2| Length = 890 Score = 35.4 bits (80), Expect = 0.14 Identities = 42/208 (20%), Positives = 83/208 (39%), Gaps = 15/208 (7%) Frame = +2 Query: 50 EKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKHAAELEV 229 E ++ ++ + + E EAA + EQA + D D + AQ A E Sbjct: 119 EAEESAKREAQQKAEREAAEQAKREAAEQAKREAAEKDKVSNQQDDMTKNAQAEKARREQ 178 Query: 230 QVSALDQQLQEAEIHYK-----NKVAEESEKLALVNTQLNKLTQNVSKSAEMEKKVQDLE 394 + + L ++ +E E H K +VAEE+ ++A + NK T N + + Sbjct: 179 EAAELKRKAEE-EAHRKLEEEARRVAEEARRMA----EENKWTDNAEPTEDSSDYHVTTS 233 Query: 395 QKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQAPSTASV----------N 544 Q + A +SD + + R+ + + ++ E + + A+V + Sbjct: 234 QHARQAEDESDREVEGGRGRGRNAKAARPKKGNKHAESKADREEARAAVRGGKGGKRKGS 293 Query: 545 PAQQQLREPSGIMAFKFILGVALLVSSL 628 QQ ++P+ + ++G + V L Sbjct: 294 SLQQGFQKPAQAVNRDVVIGETITVGEL 321 Score = 30.8 bits (68), Expect = 3.6 Identities = 21/94 (22%), Positives = 47/94 (50%), Gaps = 3/94 (3%) Frame = +2 Query: 170 KTYSADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQN 349 +T+ + A++ AAE + Q A +Q +EAE K + +++E+ A + Q Sbjct: 89 RTFVKRDPQEAERLAAEEQAQREAEEQARREAEESAKREAQQKAEREAAEQAKREAAEQA 148 Query: 350 VSKSAEMEK---KVQDLEQKLQLAYSKSDEQAKD 442 ++AE +K + D+ + Q ++ +++A + Sbjct: 149 KREAAEKDKVSNQQDDMTKNAQAEKARREQEAAE 182
>CF060_HUMAN (Q8NB25) Protein C6orf60| Length = 1020 Score = 35.4 bits (80), Expect = 0.14 Identities = 38/208 (18%), Positives = 87/208 (41%), Gaps = 39/208 (18%) Frame = +2 Query: 2 NEALTSKMQEHANLVHEKDQLE----QQLLEVRKELEAAYR------------------- 112 NE L+ +E A L + L+ QQ+LE+ K++ A R Sbjct: 291 NERLSQLEEERAFLRSKTQSLDEEQKQQILELEKKVNEAKRTQQEYYERELKNLQSRLEE 350 Query: 113 --TIANQEEQASVREIKW-----------DAYKTYSADQLEVAQKHAAE---LEVQVSAL 244 T N+ ++ E+ W +A + Q+++ ++H + LE + L Sbjct: 351 EVTQLNEAHSKTLEELAWKHHMAIEAVHSNAIRDKKKLQMDLEEQHNKDKLNLEEDKNQL 410 Query: 245 DQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEMEKKVQDLEQKLQLAYSKS 424 Q+L+ + ++K+ ++++ + + K Q + + + +QD +++LQ Sbjct: 411 QQELENLKEVLEDKLNTANQEIGHLQDMVRKSEQGLGSAEGLIASLQDSQERLQ----NE 466 Query: 425 DEQAKDAVVSTRSREFSLDSLTPQNKEQ 508 + KD++ T+ +++ Q ++Q Sbjct: 467 LDLTKDSLKETKDALLNVEGELEQERQQ 494
>KINH_HUMAN (P33176) Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC)| Length = 963 Score = 35.4 bits (80), Expect = 0.14 Identities = 42/179 (23%), Positives = 71/179 (39%), Gaps = 21/179 (11%) Frame = +2 Query: 17 SKMQ-EHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQL 193 SKM+ E +V QLE E K++E + +A + + S E K + Y L Sbjct: 595 SKMKSEVKTMVKRCKQLESTQTESNKKMEENEKELAACQLRISQHEAKIKSLTEY----L 650 Query: 194 EVAQKHAAELEVQVSALDQQL---------QEAEIHYKNKVAEESEKLALVNTQL----- 331 + ++ +LE V AL ++L E E + NKV +E V Q+ Sbjct: 651 QNVEQKKRQLEESVDALSEELVQLRAQEKVHEMEKEHLNKVQTANEVKQAVEQQIQSHRE 710 Query: 332 ------NKLTQNVSKSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLT 490 + L V A++ +QD QK+ L + + + + + + L LT Sbjct: 711 THQKQISSLRDEVEAKAKLITDLQDQNQKMMLEQERLRVEHEKLKATDQEKSRKLHELT 769
>BRE1_ASHGO (Q757D9) Ubiquitin-protein ligase BRE1 (EC 6.3.2.-)| Length = 643 Score = 35.4 bits (80), Expect = 0.14 Identities = 51/212 (24%), Positives = 91/212 (42%), Gaps = 33/212 (15%) Frame = +2 Query: 2 NEALTSKMQE-HANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTY 178 N L+++ Q L LE+ L+ +R + +A E Q S ++ D K Sbjct: 308 NNRLSAEFQTAQETLKKHNSNLEKDLVRIRTARDELLSKVAVLEAQKSKSDMLEDLEKML 367 Query: 179 SADQLEVAQKHAAELEVQVSALDQQLQEAE------IHYKNK-----VAEES--EKLALV 319 + Q ++ + E A+ ++LQ+ E Y NK V +ES KL + Sbjct: 368 ALQQEQLKALSEHKPEPARDAVMKELQDLEKAFKELSQYSNKKYSEYVNQESLMSKLTVE 427 Query: 320 NTQLNK------------------LTQNVSKSAEMEKKVQDLEQKLQLAYSKSDEQAKDA 445 T+ ++ L++N+SKS E+ ++++D+E+ LQ +K + K Sbjct: 428 KTKADQKYFAAMRSKDSILIENKNLSKNLSKSNELIQQLKDIEKSLQ---AKIENLNKQL 484 Query: 446 VVSTRSREFSLDS-LTPQNKEQDLSQAPSTAS 538 +S + + LDS T K DL+ S A+ Sbjct: 485 HISRINEKRLLDSNKTTSLKIMDLTSQLSKAN 516
>ZRF1_MOUSE (P54103) Zuotin-related factor 1| Length = 514 Score = 35.4 bits (80), Expect = 0.14 Identities = 31/172 (18%), Positives = 75/172 (43%) Frame = +2 Query: 50 EKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQKHAAELEV 229 E++++ QQ L +KE + + I + ++ W+ + AD++++ + Sbjct: 327 EEEEVRQQALLAKKEKDIQKKAIKKERQKLRNSCKSWNHFSDNEADRVKMME-------- 378 Query: 230 QVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEMEKKVQDLEQKLQL 409 +V L +L+ A + N++ S T+ V K+A +EK+++++ ++++ Sbjct: 379 EVEKLCDRLELASLQGLNEILASS-------------TREVGKAA-LEKQIEEVNEQMRR 424 Query: 410 AYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLSQAPSTASVNPAQQQLR 565 ++D + + A + S + E DL ++ PA + R Sbjct: 425 EKEEADARMRQASKNAEKSTGGSGSGSKNWSEDDLQLLIKAVNLFPAGRNSR 476
>P85AA_XENLA (Q8UUU2) Phosphatidylinositol 3-kinase regulatory alpha subunit| (PI3-kinase p85-alpha subunit) (PtdIns-3-kinase p85-alpha) (PI3K) Length = 722 Score = 35.4 bits (80), Expect = 0.14 Identities = 30/134 (22%), Positives = 56/134 (41%), Gaps = 5/134 (3%) Frame = +2 Query: 2 NEALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYS 181 N K QE+ L + + Q++ R +EA TI EEQ +E YS Sbjct: 452 NVQFEEKNQEYDRLYEDYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQE-------KYS 504 Query: 182 ADQLEVAQKHAAELEVQ-----VSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQ 346 + +E ++ E E+Q L ++ E + K ++ E+ +K N +++K Sbjct: 505 KEYIEKFRREGNEKEIQRLLHNYEKLKSRISEI-VDSKRRLEEDLKKQTAENREIDKRMN 563 Query: 347 NVSKSAEMEKKVQD 388 ++ +K +D Sbjct: 564 SIKPDLIQLRKTRD 577
>INVO_SAGOE (P24712) Involucrin| Length = 493 Score = 35.4 bits (80), Expect = 0.14 Identities = 42/198 (21%), Positives = 79/198 (39%), Gaps = 20/198 (10%) Frame = +2 Query: 38 NLVHEKDQLE--------QQLLEVRKELEAAYRTIAN----QEEQASVREIKWDAYKTYS 181 +L HE+ QLE + L ++ K+LE + +EE+ V+ + + Sbjct: 264 HLEHEEGQLELPEQVGQPKHLEQLEKQLEHPEQQEGQLKHLEEEEGQVKHLGEQEEQLKH 323 Query: 182 ADQLEVAQKHAAELEVQVSALDQQ--------LQEAEIHYKNKVAEESEKLALVNTQLNK 337 +Q E KH + E Q+ L+QQ E ++ + +S+ L QL Sbjct: 324 LEQQEEQLKHLEQQEGQLEHLEQQEGQLKHLEQHEGQLELPEQQVGQSKHLEQEEKQLEH 383 Query: 338 LTQNVSKSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKEQDLS 517 Q + + K+ LE Q+ K EQ + + + +E + L PQ +++ Sbjct: 384 PEQQEGQLKHLGKQKAQLELTEQVGQPKHLEQQEKQLEHPQQQE---EQLKPQEQQEG-- 438 Query: 518 QAPSTASVNPAQQQLREP 571 + ++QL +P Sbjct: 439 ---QLKDLEQQERQLEQP 453
>MRCKB_RAT (Q7TT49) Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1)| (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta) Length = 1713 Score = 35.4 bits (80), Expect = 0.14 Identities = 37/183 (20%), Positives = 90/183 (49%), Gaps = 5/183 (2%) Frame = +2 Query: 20 KMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEV 199 K++EH+ ++ + E + L+V++ T+ +Q+E + +I+ + K + E+ Sbjct: 645 KLREHSESFSKQMERELETLKVKQGGRGPGATLEHQQE---ISKIRSELEKKVLFYEEEL 701 Query: 200 AQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEMEKK 379 ++ A+ + ++V + +++ E+E H ++A + E L ++ +L K + + +EME+ Sbjct: 702 VRREASHV-LEVKNVKKEVHESESH---QLALQKEVL-MLKDKLEKSKR--ERHSEMEEA 754 Query: 380 VQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKE-----QDLSQAPSTASVN 544 + ++ K + + ++ K +D LT QN++ QDL+ + + Sbjct: 755 IGAMKDKYERERAMLFDENKKLTAENEKLCSFVDKLTAQNRQLEDELQDLASKKESVAHW 814 Query: 545 PAQ 553 AQ Sbjct: 815 EAQ 817 Score = 31.6 bits (70), Expect = 2.1 Identities = 29/137 (21%), Positives = 63/137 (45%), Gaps = 6/137 (4%) Frame = +2 Query: 8 ALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIAN----QEEQASVREIKWDAYKT 175 A K + H LV ++L+ Q E++ + R + E A +R K + Sbjct: 538 ARQEKEELHKQLVEASERLKSQTKELKDAHQQRKRALQEFSELNERMAELRSQKQKVSRQ 597 Query: 176 Y--SADQLEVAQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQN 349 +++EVA + + + ++ +E E ++ VAE S++ +L + +++ Sbjct: 598 LRDKEEEMEVAMQKIDSMRQDIRKSEKSRKELEARLEDAVAEASKE-----RKLREHSES 652 Query: 350 VSKSAEMEKKVQDLEQK 400 SK +ME++++ L+ K Sbjct: 653 FSK--QMERELETLKVK 667
>CING_XENLA (Q9PTD7) Cingulin| Length = 1360 Score = 35.4 bits (80), Expect = 0.14 Identities = 45/200 (22%), Positives = 80/200 (40%), Gaps = 28/200 (14%) Frame = +2 Query: 5 EALTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSA 184 EA +M++ V ++ EQ+L V+++LE+ E Q S++ + + + Sbjct: 933 EAERKRMEDSLGEVADQ---EQELAFVKRDLESKL-----DEAQRSLKRLSLEYEELQEC 984 Query: 185 DQLEVAQKHAA-----ELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQN 349 Q E+ QK ELE Q LD+ + + N E L L+ TQL + + Sbjct: 985 YQEEMKQKDHLKKTKNELEEQKRLLDKSMDKLTRELDNMSNESRGSLQLLQTQLEEYREK 1044 Query: 350 VSK----------------------SAEMEKKVQDLEQKLQ-LAYSKSDEQAKDAVVSTR 460 K S+ M+++VQ L+ LQ L K + ++S R Sbjct: 1045 SRKEIGEAQKQAKEKTAEAERHQFNSSRMQEEVQKLKLALQELQVEKETVELDKQMISQR 1104 Query: 461 SREFSLDSLTPQNKEQDLSQ 520 + D + + + D S+ Sbjct: 1105 LQSLEQDIESKKRVQDDRSR 1124
>CING_MOUSE (P59242) Cingulin| Length = 1191 Score = 35.0 bits (79), Expect = 0.19 Identities = 32/170 (18%), Positives = 72/170 (42%), Gaps = 27/170 (15%) Frame = +2 Query: 26 QEHANLVHEKDQLEQQLLEVRKELEAAYRTIA--------NQEEQASVRE------IKWD 163 Q+HA L E+ ++ + E+++ELE N+EE + ++ ++ + Sbjct: 526 QDHAALEAERQKMSSLVRELQRELEETSEETGHWQSMFQKNKEELRATKQELLQLRMEKE 585 Query: 164 AYKTYSADQLEVAQK-------------HAAELEVQVSALDQQLQEAEIHYKNKVAEESE 304 + +++EV Q+ EL+ ++ +L+E + +N+ Sbjct: 586 EMEEELGEKMEVLQRDLEQARASTRDTHQVEELKKELRRTQGELKELQAEQQNQEVTGRH 645 Query: 305 KLALVNTQLNKLTQNVSKSAEMEKKVQDLEQKLQLAYSKSDEQAKDAVVS 454 + ++ QL L + + E+E++ L++ LQ +E +K V S Sbjct: 646 RNQVLEKQLAALREEADRGRELEQQNLQLQKTLQQLRQDCEEASKAKVAS 695
>MRCKB_HUMAN (Q9Y5S2) Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1)| (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta) Length = 1711 Score = 35.0 bits (79), Expect = 0.19 Identities = 33/162 (20%), Positives = 82/162 (50%) Frame = +2 Query: 20 KMQEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEV 199 K++EH+ ++ + E + L+V++ A T+ +Q+E + +IK + K + E+ Sbjct: 645 KLREHSENFCKQMESELEALKVKQGGRGAGATLEHQQE---ISKIKSELEKKVLFYEEEL 701 Query: 200 AQKHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEMEKK 379 ++ A+ + ++V + +++ ++E H ++A + E + ++ +L K + + EME+ Sbjct: 702 VRREASHV-LEVKNVKKEVHDSESH---QLALQKE-ILMLKDKLEKSKR--ERHNEMEEA 754 Query: 380 VQDLEQKLQLAYSKSDEQAKDAVVSTRSREFSLDSLTPQNKE 505 V ++ K + + ++ K +D LT QN++ Sbjct: 755 VGTIKDKYERERAMLFDENKKLTAENEKLCSFVDKLTAQNRQ 796 Score = 30.8 bits (68), Expect = 3.6 Identities = 28/124 (22%), Positives = 56/124 (45%) Frame = +2 Query: 26 QEHANLVHEKDQLEQQLLEVRKELEAAYRTIANQEEQASVREIKWDAYKTYSADQLEVAQ 205 Q+ + E +L +++ E+R + + R + ++EE+ V K DA + ++ A+ Sbjct: 568 QQRKLALQEFSELNERMAELRAQKQKVSRQLRDKEEEMEVATQKVDAMR----QEMRRAE 623 Query: 206 KHAAELEVQVSALDQQLQEAEIHYKNKVAEESEKLALVNTQLNKLTQNVSKSAEMEKKVQ 385 K ELE Q+ + VAE S++ +L + ++N K E E + Sbjct: 624 KLRKELEAQLD--------------DAVAEASKE-----RKLREHSENFCKQMESELEAL 664 Query: 386 DLEQ 397 ++Q Sbjct: 665 KVKQ 668
>CLPB_GLOVI (Q7NFE9) Chaperone clpB| Length = 872 Score = 35.0 bits (79), Expect = 0.19 Identities = 33/137 (24%), Positives = 67/137 (48%), Gaps = 11/137 (8%) Frame = +2 Query: 11 LTSKMQEHANLVHEKDQLEQQLLEVRKELEAAYR--------TIANQEEQASVREIKWDA 166 +TSK + + + QLE + L + KE +AA R +A+ +E+ +W A Sbjct: 408 ITSKPEALDEVDRKILQLEMERLSLAKESDAASRDRLERLEKELADLKEEQRSLNAQWQA 467 Query: 167 YKTYSADQLEVAQKHAAELEVQVSALDQQL---QEAEIHYKNKVAEESEKLALVNTQLNK 337 K DQ++ ++ ++ VQ+ ++ + AE+ Y K++E ++L + QL++ Sbjct: 468 EKDI-IDQVQAVKEEIDQVNVQIQQAERDYDLNRAAELKY-GKLSELQKRLDAADKQLSE 525 Query: 338 LTQNVSKSAEMEKKVQD 388 TQ +S E+ ++ Sbjct: 526 -TQTSGRSLLREEVTEE 541 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 77,251,443 Number of Sequences: 219361 Number of extensions: 1421200 Number of successful extensions: 7168 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 6381 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 7059 length of database: 80,573,946 effective HSP length: 107 effective length of database: 57,102,319 effective search space used: 5995743495 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
