>SMG1_MOUSE (Q8BKX6) Serine/threonine-protein kinase SMG1 (EC 2.7.11.1) (SMG-1)|
          Length = 3658

 Score = 32.3 bits (72), Expect = 0.77
 Identities = 27/89 (30%), Positives = 40/89 (44%)
 Frame = +1

Query: 103  PDVSGMIRLSHGEAYLPHDKGNGAVATRLASNKSSYLLAGFGQTTTSQDVSRFLGALSTS 282
            P  S ++ L    A     +GN ++ATRL +  S   L   G+TTT+QD+ +    LST 
Sbjct: 1414 PIRSHLMELGLTAAKFARKRGNVSLATRLLAQCSEVQL---GKTTTAQDLVQHFKKLSTQ 1470

Query: 283  PDKTERTLENGSFKPNIDARLNDLKLTLG 369
                E+      + P +D     L  T G
Sbjct: 1471 GQVDEK------WGPELDIEKTKLLYTAG 1493

>SMG1_HUMAN (Q96Q15) Serine/threonine-protein kinase SMG1 (EC 2.7.11.1) (SMG-1)|
            (hSMG-1) (Lambda/iota protein kinase C-interacting
            protein) (Lambda-interacting protein) (61E3.4)
          Length = 3657

 Score = 32.3 bits (72), Expect = 0.77
 Identities = 27/89 (30%), Positives = 40/89 (44%)
 Frame = +1

Query: 103  PDVSGMIRLSHGEAYLPHDKGNGAVATRLASNKSSYLLAGFGQTTTSQDVSRFLGALSTS 282
            P  S ++ L    A     +GN ++ATRL +  S   L   G+TTT+QD+ +    LST 
Sbjct: 1412 PIRSHLMELGLTAAKFARKRGNVSLATRLLAQCSEVQL---GKTTTAQDLVQHFKKLSTQ 1468

Query: 283  PDKTERTLENGSFKPNIDARLNDLKLTLG 369
                E+      + P +D     L  T G
Sbjct: 1469 GQVDEK------WGPELDIEKTKLLYTAG 1491

>HEMH_CHLTR (O84492) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme|
           synthetase)
          Length = 314

 Score = 31.6 bits (70), Expect = 1.3
 Identities = 16/30 (53%), Positives = 19/30 (63%)
 Frame = +1

Query: 205 SYLLAGFGQTTTSQDVSRFLGALSTSPDKT 294
           +YLLA FG   TSQ++  FL AL T  D T
Sbjct: 3   TYLLANFGGPRTSQEIVSFLQALLTDRDVT 32

>ASPM_SHEEP (P62297) Abnormal spindle-like microcephaly-associated protein|
            homolog (Fragment)
          Length = 3374

 Score = 31.6 bits (70), Expect = 1.3
 Identities = 22/73 (30%), Positives = 35/73 (47%)
 Frame = +2

Query: 80   RLQAQYCGRMSLG*SG*AMVKHICLMIKAMVLLRLGWLQTSPAIFLLALVKQLLRRMSHV 259
            RLQA + GR +         +++C  I+A  +L+  W      +  L L K ++R  +H+
Sbjct: 1478 RLQAAFRGRRA---------RNLCKQIRAACVLQSCWRMRQDRLRFLNLKKNIIRLQAHI 1528

Query: 260  SWVHCQLLQTKQK 298
                 Q LQT QK
Sbjct: 1529 R--RRQQLQTYQK 1539

>CP3AE_CAVPO (Q64417) Cytochrome P450 3A14 (EC 1.14.14.1) (CYPIIIA14)|
          Length = 503

 Score = 31.2 bits (69), Expect = 1.7
 Identities = 27/87 (31%), Positives = 42/87 (48%), Gaps = 11/87 (12%)
 Frame = +1

Query: 226 GQTTTSQDVSRFLGALSTSPD-------KTERTLENGSFKPNIDA--RLNDLKLTLGPEL 378
           G  TTS  +S  + +L+T PD       + ++TL N +F P  D    +  L + +   L
Sbjct: 306 GYETTSSTLSFIMYSLATHPDVQKKLQQEIDKTLPNKAF-PTYDVMMEMEYLDMVVNETL 364

Query: 379 RIVYPLI--LNFAVSGDLELNGMVHPK 453
           R+ YP+   +      D E+NGM  PK
Sbjct: 365 RL-YPVTNRIERMSKKDFEINGMSFPK 390

>ASPM_BOVIN (P62285) Abnormal spindle-like microcephaly-associated protein|
            homolog (Fragment)
          Length = 3371

 Score = 30.8 bits (68), Expect = 2.2
 Identities = 22/73 (30%), Positives = 34/73 (46%)
 Frame = +2

Query: 80   RLQAQYCGRMSLG*SG*AMVKHICLMIKAMVLLRLGWLQTSPAIFLLALVKQLLRRMSHV 259
            RLQA + GR +         +++C  IKA  +L+  W      +  L L K ++R  +H+
Sbjct: 1475 RLQAAFRGRRA---------RNLCRQIKAACVLQSYWRMRQDRLRFLNLKKNIIRLQAHI 1525

Query: 260  SWVHCQLLQTKQK 298
                 Q L T QK
Sbjct: 1526 R--RRQQLHTYQK 1536

>SNF1_CANGA (Q00372) Carbon catabolite derepressing protein kinase (EC|
           2.7.11.1)
          Length = 612

 Score = 30.0 bits (66), Expect = 3.8
 Identities = 18/42 (42%), Positives = 23/42 (54%)
 Frame = -3

Query: 229 DQSQQEDSWTCLKPT*SQQHHCLYHEANMLHHGLTGSSQRHP 104
           DQS++EDS   + PT   Q     H ANML  GL  +S+  P
Sbjct: 434 DQSKEEDSTISILPTSLPQ----IHRANMLAQGLPAASKISP 471

>HEMH_CHLMU (Q9PJQ6) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme|
           synthetase)
          Length = 317

 Score = 29.6 bits (65), Expect = 5.0
 Identities = 15/29 (51%), Positives = 17/29 (58%)
 Frame = +1

Query: 208 YLLAGFGQTTTSQDVSRFLGALSTSPDKT 294
           YLLA FG    SQ++  FL AL T  D T
Sbjct: 4   YLLANFGGPRISQEIPSFLHALLTDQDVT 32

>HEMH_CHLCV (Q824K8) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme|
           synthetase)
          Length = 318

 Score = 29.3 bits (64), Expect = 6.5
 Identities = 18/43 (41%), Positives = 22/43 (51%)
 Frame = +1

Query: 202 SSYLLAGFGQTTTSQDVSRFLGALSTSPDKTERTLENGSFKPN 330
           S+YLLA FG    S D+  FL +L T  D T      G F P+
Sbjct: 3   SAYLLANFGGPRHSNDIEVFLTSLLTDRDVT------GGFLPS 39

>CP3AB_MOUSE (Q64459) Cytochrome P450 3A11 (EC 1.14.14.1) (CYPIIIA11)|
           (P-450IIIAM1) (P-450UT)
          Length = 504

 Score = 29.3 bits (64), Expect = 6.5
 Identities = 35/129 (27%), Positives = 54/129 (41%), Gaps = 11/129 (8%)
 Frame = +1

Query: 100 RPDVSGMIRLSHGEAYLPHDKGNGAVATRLASNKSSYLLAGFGQTTTSQDVSRFLGALST 279
           R D   ++  SH  +    DK +    + +     S +    G  TTS  +S  L +L+T
Sbjct: 268 RVDFLQLMMNSHNNS---KDKVSHKALSDMEITAQSIIFIFAGYETTSSTLSFTLHSLAT 324

Query: 280 SP-------DKTERTLENGSFKPNIDA--RLNDLKLTLGPELRIVYPLI--LNFAVSGDL 426
            P       D+ +  L N +  P  D    +  L + L   LR+ YP+   L      D+
Sbjct: 325 HPDIQKKLQDEIDEALPNKA-PPTYDTVMEMEYLDMVLNETLRL-YPIANRLERVCKKDV 382

Query: 427 ELNGMVHPK 453
           ELNG+  PK
Sbjct: 383 ELNGVYIPK 391

>CH60_CAMJR (Q5HTP2) 60 kDa chaperonin (Protein Cpn60) (groEL protein)|
          Length = 545

 Score = 29.3 bits (64), Expect = 6.5
 Identities = 32/112 (28%), Positives = 46/112 (41%), Gaps = 17/112 (15%)
 Frame = +1

Query: 73  QLQVTGS---ILRPDVSG------MIRLSHGEAYLPHDKGNGAVATRLASNKSSYLLAG- 222
           Q+Q TG    I+  D+ G      ++    G   +   K  G    R A  +   +L G 
Sbjct: 238 QIQKTGKPLLIIAEDIEGEALATLVVNKLRGVLNISAVKAPGFGDRRKAMLEDIAILTGG 297

Query: 223 ------FGQTTTSQDVSRFLGALSTSPDKTERTLENGSF-KPNIDARLNDLK 357
                  G+T  S  +     A S   DK   T+ NG+  K NIDAR+N +K
Sbjct: 298 EVISEELGRTLESATIQDLGQASSVIIDKDNTTIVNGAGEKANIDARVNQIK 349

>CH60_CAMJE (O69289) 60 kDa chaperonin (Protein Cpn60) (groEL protein)|
          Length = 545

 Score = 29.3 bits (64), Expect = 6.5
 Identities = 32/112 (28%), Positives = 46/112 (41%), Gaps = 17/112 (15%)
 Frame = +1

Query: 73  QLQVTGS---ILRPDVSG------MIRLSHGEAYLPHDKGNGAVATRLASNKSSYLLAG- 222
           Q+Q TG    I+  D+ G      ++    G   +   K  G    R A  +   +L G 
Sbjct: 238 QIQKTGKPLLIIAEDIEGEALATLVVNKLRGVLNISAVKAPGFGDRRKAMLEDIAILTGG 297

Query: 223 ------FGQTTTSQDVSRFLGALSTSPDKTERTLENGSF-KPNIDARLNDLK 357
                  G+T  S  +     A S   DK   T+ NG+  K NIDAR+N +K
Sbjct: 298 EVISEELGRTLESATIQDLGQASSVIIDKDNTTIVNGAGEKANIDARVNQIK 349

>GSPL_ECOLI (P45763) Probable general secretion pathway protein L|
          Length = 387

 Score = 29.3 bits (64), Expect = 6.5
 Identities = 20/75 (26%), Positives = 35/75 (46%)
 Frame = -3

Query: 226 QSQQEDSWTCLKPT*SQQHHCLYHEANMLHHGLTGSSQRHPAAILSL*PAAGCLLGHLKH 47
           Q QQ+++W    P   + H+  ++    L       +Q++P A+         LL HL+ 
Sbjct: 277 QQQQQETWQRYFPQIKRTHNFRFYFKQQL-------AQQYPEAVP--------LLYHLQT 321

Query: 46  FLLVYPELHISTQSY 2
            LL +PEL +   +Y
Sbjct: 322 LLLEHPELQLMEANY 336

>CP341_MOUSE (Q9JMA7) Cytochrome P450 3A41 (EC 1.14.14.1)|
          Length = 504

 Score = 28.9 bits (63), Expect = 8.5
 Identities = 32/110 (29%), Positives = 47/110 (42%), Gaps = 11/110 (10%)
 Frame = +1

Query: 157 DKGNGAVATRLASNKSSYLLAGFGQTTTSQDVSRFLGALSTSPD-------KTERTLENG 315
           DK +    + +     S +    G  TTS  +S  L  L+T PD       + + TL N 
Sbjct: 284 DKDSHKALSDMEITAQSIVFIFAGYETTSSTLSFTLYCLATHPDIQKKLQEEIDETLPNK 343

Query: 316 SFKPNIDA--RLNDLKLTLGPELRIVYPL--ILNFAVSGDLELNGMVHPK 453
           +  P  D    +  L + L   LR+ YP+   L      D+ELNG+  PK
Sbjct: 344 A-PPTYDTVMEMEYLDMVLNETLRL-YPIGNRLERFCKKDVELNGVYIPK 391

>CP4S3_DROME (Q9VXY0) Probable cytochrome P450 4s3 (EC 1.14.-.-) (CYPIVS3)|
          Length = 495

 Score = 28.9 bits (63), Expect = 8.5
 Identities = 26/82 (31%), Positives = 39/82 (47%), Gaps = 6/82 (7%)
 Frame = +1

Query: 226 GQTTTSQDVSRFLGALSTSPDKTERTLENGSFKPNIDARLND----LKLTLGPELRIVYP 393
           G  TTS  ++  L  LS +PD  +R  E  S    ++ R  +    L+  +   LRI YP
Sbjct: 308 GHDTTSSAIAFALSLLSKNPDVQQRAFEEAS---ELEGREKESMPYLEAVIKETLRI-YP 363

Query: 394 LILNFA--VSGDLELNGMVHPK 453
            +  F+  V  DLE+  +  PK
Sbjct: 364 SVPFFSRKVLEDLEVGKLTVPK 385

>WHITE_LUCCU (Q05360) Protein white|
          Length = 677

 Score = 28.9 bits (63), Expect = 8.5
 Identities = 25/66 (37%), Positives = 31/66 (46%), Gaps = 5/66 (7%)
 Frame = -2

Query: 509 ATKLTSPFSNVNIPFGLMYF----GCTMPLSSRSPLTAKFRIKG*TILNSGP-SVSFKSL 345
           A  L +  +NV+  FG +        +M LS   PLT  F + G   LNSG   V FK L
Sbjct: 536 ALALVTLVANVSTSFGYLISCASTSTSMALSVGPPLTIPFLLFGGVFLNSGSVPVYFKWL 595

Query: 344 SRASMF 327
           S  S F
Sbjct: 596 SYFSWF 601

>ACH3_CAEEL (P54244) Acetylcholine receptor, alpha-type subunit deg-3 precursor|
          Length = 564

 Score = 28.9 bits (63), Expect = 8.5
 Identities = 25/97 (25%), Positives = 40/97 (41%), Gaps = 7/97 (7%)
 Frame = -2

Query: 509 ATKLTSPFSNVNIPFGL-------MYFGCTMPLSSRSPLTAKFRIKG*TILNSGPSVSFK 351
           +TK+ SP S + +P            F      S  SP TA+ R    ++  S    +  
Sbjct: 422 STKMASPMSTLRVPQSAGSVSEKRQSFQMIDVTSPNSPNTARSRAP--SLAPSTAKATMW 479

Query: 350 SLSRASMFGLKLPFSRVLSVLSGEVDSAPRKRETSCE 240
             + +++ G      R  +V + EVD   RKR+ S E
Sbjct: 480 EGTMSALAGTNTQLRRTSNVFNKEVDEMRRKRQCSLE 516

>DPOE1_MOUSE (Q9WVF7) DNA polymerase epsilon, catalytic subunit A (EC 2.7.7.7)|
            (DNA polymerase II subunit A)
          Length = 2283

 Score = 28.9 bits (63), Expect = 8.5
 Identities = 13/45 (28%), Positives = 26/45 (57%)
 Frame = +2

Query: 179  RLGWLQTSPAIFLLALVKQLLRRMSHVSWVHCQLLQTKQKGLLRM 313
            RLG ++  P+  L + +++  R +  + W   Q+ +T+Q GL R+
Sbjct: 1302 RLGPIREGPSTGLGSFLRKTARSIMDLPWQIIQISETRQAGLFRL 1346


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.316    0.136    0.380 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 73,559,613
Number of Sequences: 219361
Number of extensions: 1434632
Number of successful extensions: 3794
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 3731
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3793
length of database: 80,573,946
effective HSP length: 104
effective length of database: 57,760,402
effective search space used: 3754426130
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.5 bits)