ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
menu 
| Clone Name | basd25c14 |
|---|---|
| Clone Library Name | barley_pub |
>APK1B_ARATH (P46573) Protein kinase APK1B, chloroplast precursor (EC 2.7.11.1)| Length = 412 Score = 154 bits (390), Expect = 1e-37 Identities = 72/94 (76%), Positives = 82/94 (87%) Frame = +1 Query: 271 EKEILQSSNLRKFTFSELKSCTRNFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIV 450 E EILQS NL+ FTF+ELK+ TRNFR DS+LGEGGFGSVFKGWIDE+T T KPGTG+++ Sbjct: 45 EGEILQSPNLKSFTFAELKAATRNFRPDSVLGEGGFGSVFKGWIDEQTLTASKPGTGVVI 104 Query: 451 AVKKLKLDSFQGHKEWLAEVNYLGQLSHPNLVKL 552 AVKKL D +QGH+EWLAEVNYLGQ SHPNLVKL Sbjct: 105 AVKKLNQDGWQGHQEWLAEVNYLGQFSHPNLVKL 138
>NAK_ARATH (P43293) Probable serine/threonine-protein kinase NAK (EC 2.7.11.1)| Length = 389 Score = 147 bits (372), Expect = 1e-35 Identities = 66/94 (70%), Positives = 80/94 (85%) Frame = +1 Query: 271 EKEILQSSNLRKFTFSELKSCTRNFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIV 450 E EILQ++NL+ F+ SELKS TRNFR DS++GEGGFG VFKGWIDE + P KPGTG+++ Sbjct: 44 EGEILQNANLKNFSLSELKSATRNFRPDSVVGEGGFGCVFKGWIDESSLAPSKPGTGIVI 103 Query: 451 AVKKLKLDSFQGHKEWLAEVNYLGQLSHPNLVKL 552 AVK+L + FQGH+EWLAE+NYLGQL HPNLVKL Sbjct: 104 AVKRLNQEGFQGHREWLAEINYLGQLDHPNLVKL 137
>APK1A_ARATH (Q06548) Protein kinase APK1A, chloroplast precursor (EC 2.7.11.1)| Length = 410 Score = 145 bits (365), Expect = 1e-34 Identities = 67/94 (71%), Positives = 80/94 (85%) Frame = +1 Query: 271 EKEILQSSNLRKFTFSELKSCTRNFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIV 450 E EILQS NL+ F+F+ELKS TRNFR DS+LGEGGFG VFKGWIDE++ T +PGTG+++ Sbjct: 44 EGEILQSPNLKSFSFAELKSATRNFRPDSVLGEGGFGCVFKGWIDEKSLTASRPGTGLVI 103 Query: 451 AVKKLKLDSFQGHKEWLAEVNYLGQLSHPNLVKL 552 AVKKL D +QGH+EWLAEVNYLGQ SH +LVKL Sbjct: 104 AVKKLNQDGWQGHQEWLAEVNYLGQFSHRHLVKL 137
>CX32_ARATH (P27450) Probable serine/threonine-protein kinase Cx32, chloroplast| precursor (EC 2.7.11.1) Length = 419 Score = 115 bits (288), Expect = 8e-26 Identities = 50/92 (54%), Positives = 71/92 (77%) Frame = +1 Query: 277 EILQSSNLRKFTFSELKSCTRNFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAV 456 ++L+S NL+ + F +LK+ T+NF+ DS+LG+GGFG V++GW+D T P + G+GMIVA+ Sbjct: 64 KLLESPNLKVYNFLDLKTATKNFKPDSMLGQGGFGKVYRGWVDATTLAPSRVGSGMIVAI 123 Query: 457 KKLKLDSFQGHKEWLAEVNYLGQLSHPNLVKL 552 K+L +S QG EW +EVN+LG LSH NLVKL Sbjct: 124 KRLNSESVQGFAEWRSEVNFLGMLSHRNLVKL 155
>PBS1_ARATH (Q9FE20) Serine/threonine-protein kinase PBS1 (EC 2.7.11.1)| (AvrPphB susceptible protein 1) Length = 456 Score = 75.5 bits (184), Expect = 9e-14 Identities = 40/82 (48%), Positives = 50/82 (60%) Frame = +1 Query: 307 FTFSELKSCTRNFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQG 486 F F EL + T NF D+ LGEGGFG V+KG +D TG +VAVK+L + QG Sbjct: 74 FAFRELAAATMNFHPDTFLGEGGFGRVYKGRLD---------STGQVVAVKQLDRNGLQG 124 Query: 487 HKEWLAEVNYLGQLSHPNLVKL 552 ++E+L EV L L HPNLV L Sbjct: 125 NREFLVEVLMLSLLHHPNLVNL 146
>RLCK7_ARATH (Q9LQQ8) Probable serine/threonine-protein kinase RLCKVII (EC| 2.7.11.1) Length = 423 Score = 72.0 bits (175), Expect = 1e-12 Identities = 39/82 (47%), Positives = 49/82 (59%) Frame = +1 Query: 307 FTFSELKSCTRNFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQG 486 FTF EL T NFR+D LGEGGFG VFKG I++ +VA+K+L + QG Sbjct: 91 FTFQELAEATGNFRSDCFLGEGGFGKVFKGTIEK---------LDQVVAIKQLDRNGVQG 141 Query: 487 HKEWLAEVNYLGQLSHPNLVKL 552 +E++ EV L HPNLVKL Sbjct: 142 IREFVVEVLTLSLADHPNLVKL 163
>BRI1_LYCPE (Q8L899) Systemin receptor SR160 precursor (EC 2.7.11.1)| (Brassinosteroid LRR receptor kinase) Length = 1207 Score = 67.0 bits (162), Expect = 3e-11 Identities = 36/85 (42%), Positives = 50/85 (58%) Frame = +1 Query: 298 LRKFTFSELKSCTRNFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDS 477 LRK TF++L T F DSL+G GGFG V+K + + G +VA+KKL S Sbjct: 873 LRKLTFADLLEATNGFHNDSLVGSGGFGDVYKAQLKD----------GSVVAIKKLIHVS 922 Query: 478 FQGHKEWLAEVNYLGQLSHPNLVKL 552 QG +E+ AE+ +G++ H NLV L Sbjct: 923 GQGDREFTAEMETIGKIKHRNLVPL 947
>BRI1_LYCES (Q8GUQ5) Brassinosteroid LRR receptor kinase precursor (EC 2.7.11.1)| (tBRI1) (Altered brassinolide sensitivity 1) (Systemin receptor SR160) Length = 1207 Score = 67.0 bits (162), Expect = 3e-11 Identities = 36/85 (42%), Positives = 50/85 (58%) Frame = +1 Query: 298 LRKFTFSELKSCTRNFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDS 477 LRK TF++L T F DSL+G GGFG V+K + + G +VA+KKL S Sbjct: 873 LRKLTFADLLEATNGFHNDSLVGSGGFGDVYKAQLKD----------GSVVAIKKLIHVS 922 Query: 478 FQGHKEWLAEVNYLGQLSHPNLVKL 552 QG +E+ AE+ +G++ H NLV L Sbjct: 923 GQGDREFTAEMETIGKIKHRNLVPL 947
>BRI1_ARATH (O22476) BRASSINOSTEROID INSENSITIVE 1 precursor (EC 2.7.11.1)| (AtBRI1) (Brassinosteroid LRR receptor kinase) Length = 1196 Score = 66.6 bits (161), Expect = 4e-11 Identities = 36/85 (42%), Positives = 50/85 (58%) Frame = +1 Query: 298 LRKFTFSELKSCTRNFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDS 477 LRK TF++L T F DSL+G GGFG V+K + + G VA+KKL S Sbjct: 868 LRKLTFADLLQATNGFHNDSLIGSGGFGDVYKAILKD----------GSAVAIKKLIHVS 917 Query: 478 FQGHKEWLAEVNYLGQLSHPNLVKL 552 QG +E++AE+ +G++ H NLV L Sbjct: 918 GQGDREFMAEMETIGKIKHRNLVPL 942
>BRL3_ARATH (Q9LJF3) Serine/threonine-protein kinase BRI1-like 3 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 3) Length = 1164 Score = 65.9 bits (159), Expect = 7e-11 Identities = 35/85 (41%), Positives = 49/85 (57%) Frame = +1 Query: 298 LRKFTFSELKSCTRNFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDS 477 LRK TF+ L T F DS++G GGFG V+K K G +VA+KKL + Sbjct: 843 LRKLTFAHLLEATNGFSADSMIGSGGFGDVYK----------AKLADGSVVAIKKLIQVT 892 Query: 478 FQGHKEWLAEVNYLGQLSHPNLVKL 552 QG +E++AE+ +G++ H NLV L Sbjct: 893 GQGDREFMAEMETIGKIKHRNLVPL 917
>BRL2_ARATH (Q9ZPS9) Serine/threonine-protein kinase BRI1-like 2 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 2) (Protein VASCULAR HIGHWAY 1) Length = 1143 Score = 63.2 bits (152), Expect = 5e-10 Identities = 36/85 (42%), Positives = 48/85 (56%) Frame = +1 Query: 298 LRKFTFSELKSCTRNFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDS 477 LRK FS+L T F S++G GGFG VFK + + G VA+KKL S Sbjct: 823 LRKLKFSQLIEATNGFSAASMIGHGGFGEVFKATLKD----------GSSVAIKKLIRLS 872 Query: 478 FQGHKEWLAEVNYLGQLSHPNLVKL 552 QG +E++AE+ LG++ H NLV L Sbjct: 873 CQGDREFMAEMETLGKIKHRNLVPL 897
>BRL1_ARATH (Q9ZWC8) Serine/threonine-protein kinase BRI1-like 1 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 1) Length = 1166 Score = 62.4 bits (150), Expect = 8e-10 Identities = 32/85 (37%), Positives = 50/85 (58%) Frame = +1 Query: 298 LRKFTFSELKSCTRNFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDS 477 LRK TF+ L T F ++++G GGFG V+K + + G +VA+KKL + Sbjct: 844 LRKLTFAHLLEATNGFSAETMVGSGGFGEVYKAQLRD----------GSVVAIKKLIRIT 893 Query: 478 FQGHKEWLAEVNYLGQLSHPNLVKL 552 QG +E++AE+ +G++ H NLV L Sbjct: 894 GQGDREFMAEMETIGKIKHRNLVPL 918
>EXS_ARATH (Q9LYN8) Leucine-rich repeat receptor protein kinase EXS precursor| (EC 2.7.11.1) (Extra sporogenous cells protein) (EXCESS MICROSPOROCYTES1 protein) Length = 1192 Score = 57.0 bits (136), Expect = 3e-08 Identities = 32/85 (37%), Positives = 49/85 (57%) Frame = +1 Query: 298 LRKFTFSELKSCTRNFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDS 477 L K ++ T +F +++G+GGFG+V+K + PG VAVKKL Sbjct: 902 LLKVRLGDIVEATDHFSKKNIIGDGGFGTVYKACL---------PGE-KTVAVKKLSEAK 951 Query: 478 FQGHKEWLAEVNYLGQLSHPNLVKL 552 QG++E++AE+ LG++ HPNLV L Sbjct: 952 TQGNREFMAEMETLGKVKHPNLVSL 976
>NORK_MEDTR (Q8L4H4) Nodulation receptor kinase precursor (EC 2.7.11.1) (Does| not make infections protein 2) (Symbiosis receptor-like kinase) (MtSYMRK) Length = 925 Score = 56.6 bits (135), Expect = 5e-08 Identities = 33/90 (36%), Positives = 51/90 (56%) Frame = +1 Query: 283 LQSSNLRKFTFSELKSCTRNFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKK 462 ++S +++ FT ++ T ++T L+GEGGFGSV++G +D+ G VAVK Sbjct: 578 IKSVSVKPFTLEYIEQATEQYKT--LIGEGGFGSVYRGTLDD----------GQEVAVKV 625 Query: 463 LKLDSFQGHKEWLAEVNYLGQLSHPNLVKL 552 S QG +E+ E+N L + H NLV L Sbjct: 626 RSSTSTQGTREFDNELNLLSAIQHENLVPL 655
>NORK_PEA (Q8LKZ1) Nodulation receptor kinase precursor (EC 2.7.11.1)| Length = 924 Score = 56.2 bits (134), Expect = 6e-08 Identities = 33/90 (36%), Positives = 51/90 (56%) Frame = +1 Query: 283 LQSSNLRKFTFSELKSCTRNFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKK 462 ++S +++ FT ++ T ++T L+GEGGFGSV++G +D+ G VAVK Sbjct: 577 IKSVSVKPFTLEYIELATEKYKT--LIGEGGFGSVYRGTLDD----------GQEVAVKV 624 Query: 463 LKLDSFQGHKEWLAEVNYLGQLSHPNLVKL 552 S QG +E+ E+N L + H NLV L Sbjct: 625 RSATSTQGTREFDNELNLLSAIQHENLVPL 654
>SIRK_ARATH (O64483) Senescence-induced receptor-like serine/threonine-protein| kinase precursor (FLG22-induced receptor-like kinase 1) Length = 876 Score = 54.3 bits (129), Expect = 2e-07 Identities = 34/84 (40%), Positives = 49/84 (58%) Frame = +1 Query: 301 RKFTFSELKSCTRNFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSF 480 R F +SE+ + T NF + ++G+GGFG V+ G I+ G VAVK L +S Sbjct: 562 RYFKYSEVVNITNNF--ERVIGKGGFGKVYHGVIN-----------GEQVAVKVLSEESA 608 Query: 481 QGHKEWLAEVNYLGQLSHPNLVKL 552 QG+KE+ AEV+ L ++ H NL L Sbjct: 609 QGYKEFRAEVDLLMRVHHTNLTSL 632
>PSKR_ARATH (Q9ZVR7) Putative phytosulfokine receptor precursor (EC 2.7.11.1)| (Phytosulfokine LRR receptor kinase) Length = 1008 Score = 53.1 bits (126), Expect = 5e-07 Identities = 32/91 (35%), Positives = 49/91 (53%) Frame = +1 Query: 280 ILQSSNLRKFTFSELKSCTRNFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVK 459 +L SN ++ ++ +L T +F +++G GGFG V+K + + G VA+K Sbjct: 713 VLFQSNDKELSYDDLLDSTNSFDQANIIGCGGFGMVYKATLPD----------GKKVAIK 762 Query: 460 KLKLDSFQGHKEWLAEVNYLGQLSHPNLVKL 552 KL D Q +E+ AEV L + HPNLV L Sbjct: 763 KLSGDCGQIEREFEAEVETLSRAQHPNLVLL 793
>BAK1_ARATH (Q94F62) BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1| precursor (EC 2.7.11.1) (BRI1-associated receptor kinase 1) (Somatic embryogenesis receptor-like kinase 3) Length = 615 Score = 52.4 bits (124), Expect = 9e-07 Identities = 30/86 (34%), Positives = 49/86 (56%), Gaps = 1/86 (1%) Frame = +1 Query: 298 LRKFTFSELKSCTRNFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDS 477 L++F+ EL+ + NF ++LG GGFG V+KG + + G +VAVK+LK + Sbjct: 274 LKRFSLRELQVASDNFSNKNILGRGGFGKVYKGRLAD----------GTLVAVKRLKEER 323 Query: 478 FQGHK-EWLAEVNYLGQLSHPNLVKL 552 QG + ++ EV + H NL++L Sbjct: 324 TQGGELQFQTEVEMISMAVHRNLLRL 349
>KPRO_MAIZE (P17801) Putative receptor protein kinase ZmPK1 precursor (EC| 2.7.11.1) Length = 817 Score = 50.1 bits (118), Expect = 4e-06 Identities = 30/88 (34%), Positives = 54/88 (61%) Frame = +1 Query: 289 SSNLRKFTFSELKSCTRNFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLK 468 +SN R++++ EL TR F+ + LG G G+V+KG +++ VAVKKL+ Sbjct: 518 TSNFRRYSYRELVKATRKFKVE--LGRGESGTVYKGVLEDDRH----------VAVKKLE 565 Query: 469 LDSFQGHKEWLAEVNYLGQLSHPNLVKL 552 + QG + + AE++ +G+++H NLV++ Sbjct: 566 -NVRQGKEVFQAELSVIGRINHMNLVRI 592
>SRK6_BRAOE (Q09092) Putative serine/threonine-protein kinase receptor| precursor (EC 2.7.11.1) (S-receptor kinase) (SRK) Length = 849 Score = 48.9 bits (115), Expect = 9e-06 Identities = 28/73 (38%), Positives = 42/73 (57%) Frame = +1 Query: 334 TRNFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEWLAEVN 513 T NF + + LG+GGFG V+KG + + G +AVK+L S QG E++ EV Sbjct: 525 TENFSSCNKLGQGGFGIVYKGRLLD----------GKEIAVKRLSKTSVQGTDEFMNEVT 574 Query: 514 YLGQLSHPNLVKL 552 + +L H NLV++ Sbjct: 575 LIARLQHINLVQV 587
>RYK_AVIR3 (P33497) Tyrosine-protein kinase transforming protein RYK (EC| 2.7.10.1) Length = 442 Score = 47.8 bits (112), Expect = 2e-05 Identities = 28/67 (41%), Positives = 40/67 (59%), Gaps = 2/67 (2%) Frame = +1 Query: 358 LLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGH--KEWLAEVNYLGQLS 531 +LGEG FGSV +G + + TP K VAVK +KLD+F +E+L+E + Sbjct: 50 VLGEGEFGSVMEGRLSQPEGTPQK------VAVKTMKLDNFSHREIEEFLSEAACIKDFD 103 Query: 532 HPNLVKL 552 HPN++KL Sbjct: 104 HPNVIKL 110
>TMK1_ARATH (P43298) Putative receptor protein kinase TMK1 precursor (EC| 2.7.11.1) Length = 942 Score = 47.4 bits (111), Expect = 3e-05 Identities = 28/77 (36%), Positives = 43/77 (55%) Frame = +1 Query: 322 LKSCTRNFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEWL 501 L+S T NF +D++LG GGFG V+KG + + T VK ++A K G E+ Sbjct: 581 LRSVTNNFSSDNILGSGGFGVVYKGELHDGTKIAVKRMENGVIAGK--------GFAEFK 632 Query: 502 AEVNYLGQLSHPNLVKL 552 +E+ L ++ H +LV L Sbjct: 633 SEIAVLTKVRHRHLVTL 649
>PSKR_DAUCA (Q8LPB4) Phytosulfokine receptor precursor (EC 2.7.11.1)| (Phytosulfokine LRR receptor kinase) Length = 1021 Score = 47.0 bits (110), Expect = 4e-05 Identities = 27/83 (32%), Positives = 44/83 (53%) Frame = +1 Query: 304 KFTFSELKSCTRNFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQ 483 + + ++ T +F +++G GGFG V+K + + G VA+K+L D+ Q Sbjct: 730 ELSLDDILKSTSSFNQANIIGCGGFGLVYKATLPD----------GTKVAIKRLSGDTGQ 779 Query: 484 GHKEWLAEVNYLGQLSHPNLVKL 552 +E+ AEV L + HPNLV L Sbjct: 780 MDREFQAEVETLSRAQHPNLVHL 802
>IRAK4_HUMAN (Q9NWZ3) Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1)| (IRAK-4) (NY-REN-64 antigen) Length = 460 Score = 47.0 bits (110), Expect = 4e-05 Identities = 31/102 (30%), Positives = 53/102 (51%), Gaps = 8/102 (7%) Frame = +1 Query: 271 EKEILQSSNLR--KFTFSELKSCTRNFRTDSL------LGEGGFGSVFKGWIDERTFTPV 426 E + L+ S+ R F+F ELK+ T NF + +GEGGFG V+KG+++ T Sbjct: 154 ENKSLEVSDTRFHSFSFYELKNVTNNFDERPISVGGNKMGEGGFGVVYKGYVNNTTVAVK 213 Query: 427 KPGTGMIVAVKKLKLDSFQGHKEWLAEVNYLGQLSHPNLVKL 552 K + + ++LK +++ E+ + + H NLV+L Sbjct: 214 KLAAMVDITTEELK-------QQFDQEIKVMAKCQHENLVEL 248
>CRI4_MAIZE (O24585) Putative receptor protein kinase CRINKLY4 precursor (EC| 2.7.11.1) Length = 901 Score = 46.6 bits (109), Expect = 5e-05 Identities = 30/96 (31%), Positives = 51/96 (53%), Gaps = 2/96 (2%) Frame = +1 Query: 271 EKEILQSSNLRKFTFSELKSCTRNFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIV 450 + E L+ ++F++ EL+ T F DS +G+G F VFKG + + G +V Sbjct: 481 DMEDLKIRRAQEFSYEELEQATGGFSEDSQVGKGSFSCVFKGILRD----------GTVV 530 Query: 451 AVKKL--KLDSFQGHKEWLAEVNYLGQLSHPNLVKL 552 AVK+ D + KE+ E++ L +L+H +L+ L Sbjct: 531 AVKRAIKASDVKKSSKEFHNELDLLSRLNHAHLLNL 566
>IRAK4_MOUSE (Q8R4K2) Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1)| (IRAK-4) Length = 459 Score = 46.2 bits (108), Expect = 6e-05 Identities = 31/98 (31%), Positives = 51/98 (52%), Gaps = 8/98 (8%) Frame = +1 Query: 283 LQSSNLR--KFTFSELKSCTRNFRTD------SLLGEGGFGSVFKGWIDERTFTPVKPGT 438 ++SS+ R F+F ELKS T NF + +GEGGFG V+KG ++ K G Sbjct: 158 VESSDTRFHSFSFHELKSITNNFDEQPASAGGNRMGEGGFGVVYKGCVNNTIVAVKKLGA 217 Query: 439 GMIVAVKKLKLDSFQGHKEWLAEVNYLGQLSHPNLVKL 552 + ++ ++LK +++ E+ + H NLV+L Sbjct: 218 MVEISTEELK-------QQFDQEIKVMATCQHENLVEL 248
>MERTK_HUMAN (Q12866) Proto-oncogene tyrosine-protein kinase MER precursor (EC| 2.7.10.1) (C-mer) (Receptor tyrosine kinase MerTK) Length = 999 Score = 45.8 bits (107), Expect = 8e-05 Identities = 27/67 (40%), Positives = 42/67 (62%), Gaps = 2/67 (2%) Frame = +1 Query: 358 LLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLD--SFQGHKEWLAEVNYLGQLS 531 +LGEG FGSV +G + + + GT + VAVK +KLD S + +E+L+E + S Sbjct: 592 ILGEGEFGSVMEGNLKQ------EDGTSLKVAVKTMKLDNSSHREIEEFLSEAACMKDFS 645 Query: 532 HPNLVKL 552 HPN+++L Sbjct: 646 HPNVIRL 652
>MERTK_MOUSE (Q60805) Proto-oncogene tyrosine-protein kinase MER precursor (EC| 2.7.10.1) (C-mer) (Receptor tyrosine kinase MerTK) Length = 994 Score = 45.8 bits (107), Expect = 8e-05 Identities = 26/67 (38%), Positives = 41/67 (61%), Gaps = 2/67 (2%) Frame = +1 Query: 358 LLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGH--KEWLAEVNYLGQLS 531 +LGEG FGSV +G + + + GT VAVK +KLD+F +E+L+E + + Sbjct: 587 VLGEGEFGSVMEGNLKQ------EDGTSQKVAVKTMKLDNFSQREIEEFLSEAACMKDFN 640 Query: 532 HPNLVKL 552 HPN+++L Sbjct: 641 HPNVIRL 647
>MERTK_RAT (P57097) Proto-oncogene tyrosine-protein kinase MER precursor (EC| 2.7.10.1) (C-mer) (Receptor tyrosine kinase MerTK) Length = 994 Score = 45.1 bits (105), Expect = 1e-04 Identities = 26/67 (38%), Positives = 42/67 (62%), Gaps = 2/67 (2%) Frame = +1 Query: 358 LLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSF--QGHKEWLAEVNYLGQLS 531 +LGEG FGSV +G + + + GT VAVK +KLD+F + +E+L+E + + Sbjct: 587 VLGEGEFGSVMEGNLKQ------EDGTSQKVAVKTMKLDNFSLREIEEFLSEAACMKDFN 640 Query: 532 HPNLVKL 552 HPN+++L Sbjct: 641 HPNVIRL 647
>FER_HUMAN (P16591) Proto-oncogene tyrosine-protein kinase FER (EC 2.7.10.2)| (p94-FER) (c-FER) Length = 822 Score = 42.0 bits (97), Expect = 0.001 Identities = 28/66 (42%), Positives = 36/66 (54%), Gaps = 1/66 (1%) Frame = +1 Query: 358 LLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHK-EWLAEVNYLGQLSH 534 LLG+G FG V+KG + ++T VAVK K D Q K ++L E L Q H Sbjct: 568 LLGKGNFGEVYKGTLKDKT----------SVAVKTCKEDLPQELKIKFLQEAKILKQYDH 617 Query: 535 PNLVKL 552 PN+VKL Sbjct: 618 PNIVKL 623
>EPB1B_XENLA (Q91736) Ephrin type-B receptor 1-B (EC 2.7.10.1) (Tyrosine-protein| kinase receptor XELK) (Fragment) Length = 902 Score = 42.0 bits (97), Expect = 0.001 Identities = 28/92 (30%), Positives = 47/92 (51%), Gaps = 10/92 (10%) Frame = +1 Query: 307 FTFSELKSCTRNF---------RTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVK 459 FT+ + R F + + ++G G FG V+KG R P K + VA+K Sbjct: 516 FTYEDPNEAVREFAKEIDVSFVKIEEVIGAGEFGEVYKG----RLKLPSK--REISVAIK 569 Query: 460 KLKLD-SFQGHKEWLAEVNYLGQLSHPNLVKL 552 LK S + +++L+E + +GQ HPN+++L Sbjct: 570 TLKAGYSEKQRRDFLSEASIMGQFDHPNIIRL 601
>EPHB1_RAT (P09759) Ephrin type-B receptor 1 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH-2) (ELK) Length = 984 Score = 42.0 bits (97), Expect = 0.001 Identities = 28/93 (30%), Positives = 47/93 (50%), Gaps = 11/93 (11%) Frame = +1 Query: 307 FTFSELKSCTRNF---------RTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMI-VAV 456 FT+ + R F + + ++G G FG V+KG + PG I VA+ Sbjct: 598 FTYEDPNEAVREFAKEIDVSFVKIEEVIGAGEFGEVYKGRLK-------LPGKREIYVAI 650 Query: 457 KKLKLD-SFQGHKEWLAEVNYLGQLSHPNLVKL 552 K LK S + +++L+E + +GQ HPN+++L Sbjct: 651 KTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRL 683
>EPHB1_HUMAN (P54762) Ephrin type-B receptor 1 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH-2) (NET) (HEK6) (ELK) Length = 984 Score = 42.0 bits (97), Expect = 0.001 Identities = 28/93 (30%), Positives = 47/93 (50%), Gaps = 11/93 (11%) Frame = +1 Query: 307 FTFSELKSCTRNF---------RTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMI-VAV 456 FT+ + R F + + ++G G FG V+KG + PG I VA+ Sbjct: 598 FTYEDPNEAVREFAKEIDVSFVKIEEVIGAGEFGEVYKGRLK-------LPGKREIYVAI 650 Query: 457 KKLKLD-SFQGHKEWLAEVNYLGQLSHPNLVKL 552 K LK S + +++L+E + +GQ HPN+++L Sbjct: 651 KTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRL 683
>EPHB1_CHICK (Q07494) Ephrin type-B receptor 1 (EC 2.7.10.1) (Tyrosine-protein| kinase receptor EPH-2) (Tyrosine kinase CEK6 receptor) (Fragment) Length = 984 Score = 42.0 bits (97), Expect = 0.001 Identities = 28/93 (30%), Positives = 47/93 (50%), Gaps = 11/93 (11%) Frame = +1 Query: 307 FTFSELKSCTRNF---------RTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMI-VAV 456 FT+ + R F + + ++G G FG V+KG + PG I VA+ Sbjct: 598 FTYEDPNEAVREFAKEIDVSFVKIEEVIGAGEFGEVYKGRLK-------LPGKREIYVAI 650 Query: 457 KKLKLD-SFQGHKEWLAEVNYLGQLSHPNLVKL 552 K LK S + +++L+E + +GQ HPN+++L Sbjct: 651 KTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRL 683
>EPB1A_XENLA (Q91571) Ephrin type-B receptor 1-A precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor XEK) Length = 985 Score = 42.0 bits (97), Expect = 0.001 Identities = 28/92 (30%), Positives = 47/92 (51%), Gaps = 10/92 (10%) Frame = +1 Query: 307 FTFSELKSCTRNF---------RTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVK 459 FT+ + R F + + ++G G FG V+KG R P K + VA+K Sbjct: 599 FTYEDPNEAVREFAKEIDVSFVKIEEVIGAGEFGEVYKG----RLKLPSK--REISVAIK 652 Query: 460 KLKLD-SFQGHKEWLAEVNYLGQLSHPNLVKL 552 LK S + +++L+E + +GQ HPN+++L Sbjct: 653 TLKAGYSEKQRRDFLSEASIMGQFDHPNIIRL 684
>CDK2_XENLA (P23437) Cell division protein kinase 2 (EC 2.7.11.22) (CDC2| homolog Eg1 protein kinase) Length = 297 Score = 42.0 bits (97), Expect = 0.001 Identities = 28/73 (38%), Positives = 43/73 (58%), Gaps = 2/73 (2%) Frame = +1 Query: 340 NFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDS-FQGHKEW-LAEVN 513 NF+ +GEG +G V+K E TG IVA+KK++LD+ +G + E++ Sbjct: 3 NFQKVEKIGEGTYGVVYKARNRE---------TGEIVALKKIRLDTETEGVPSTAIREIS 53 Query: 514 YLGQLSHPNLVKL 552 L +L+HPN+VKL Sbjct: 54 LLKELNHPNIVKL 66
>IRAK1_MOUSE (Q62406) Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1)| (IRAK-1) (IRAK) (Pelle-like protein kinase) (mPLK) Length = 710 Score = 41.6 bits (96), Expect = 0.002 Identities = 27/82 (32%), Positives = 40/82 (48%), Gaps = 4/82 (4%) Frame = +1 Query: 313 FSELKSCTRNFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLK----LDSF 480 F E+ T NF + +GEGGFG V++ + T+ AVK+LK L+ Sbjct: 202 FCEISQGTCNFSEELRIGEGGFGCVYRAVMRNTTY-----------AVKRLKEEADLEWT 250 Query: 481 QGHKEWLAEVNYLGQLSHPNLV 546 + +L EV L + HPN+V Sbjct: 251 MVKQSFLTEVEQLSRFRHPNIV 272
>JAK2_RAT (Q62689) Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2)| (JAK-2) Length = 1132 Score = 41.6 bits (96), Expect = 0.002 Identities = 23/63 (36%), Positives = 37/63 (58%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEWLAEVNYLGQLSHPN 540 LG+G FGSV + + P++ TG +VAVKKL+ + + +++ E+ L L H N Sbjct: 855 LGKGNFGSV-----EMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEILKSLQHDN 909 Query: 541 LVK 549 +VK Sbjct: 910 IVK 912
>JAK2_HUMAN (O60674) Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2)| (JAK-2) Length = 1132 Score = 41.6 bits (96), Expect = 0.002 Identities = 23/63 (36%), Positives = 37/63 (58%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEWLAEVNYLGQLSHPN 540 LG+G FGSV + + P++ TG +VAVKKL+ + + +++ E+ L L H N Sbjct: 855 LGKGNFGSV-----EMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEILKSLQHDN 909 Query: 541 LVK 549 +VK Sbjct: 910 IVK 912
>JAK2_MOUSE (Q62120) Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2)| (JAK-2) Length = 1129 Score = 41.6 bits (96), Expect = 0.002 Identities = 23/63 (36%), Positives = 37/63 (58%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEWLAEVNYLGQLSHPN 540 LG+G FGSV + + P++ TG +VAVKKL+ + + +++ E+ L L H N Sbjct: 855 LGKGNFGSV-----EMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEILKSLQHDN 909 Query: 541 LVK 549 +VK Sbjct: 910 IVK 912
>FLK_RAT (P09760) Tyrosine-protein kinase FLK (EC 2.7.10.2) (Fragment)| Length = 323 Score = 41.6 bits (96), Expect = 0.002 Identities = 28/66 (42%), Positives = 36/66 (54%), Gaps = 1/66 (1%) Frame = +1 Query: 358 LLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHK-EWLAEVNYLGQLSH 534 LLG+G FG V+KG + ++T VAVK K D Q K ++L E L Q H Sbjct: 69 LLGKGNFGEVYKGTLKDKT----------PVAVKTCKEDLPQELKIKFLQEAKILKQYDH 118 Query: 535 PNLVKL 552 PN+VKL Sbjct: 119 PNIVKL 124
>TYK2_HUMAN (P29597) Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)| Length = 1187 Score = 41.2 bits (95), Expect = 0.002 Identities = 26/64 (40%), Positives = 33/64 (51%), Gaps = 1/64 (1%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKE-WLAEVNYLGQLSHP 537 LGEG FG V D P GTG +VAVK LK D H+ W E++ L L H Sbjct: 903 LGEGHFGKVSLYCYD-----PTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 Query: 538 NLVK 549 +++K Sbjct: 958 HIIK 961
>CC2H3_TRYBB (P54666) Cell division control protein 2 homolog 3 (EC 2.7.11.22)| Length = 311 Score = 40.8 bits (94), Expect = 0.003 Identities = 29/81 (35%), Positives = 44/81 (54%), Gaps = 2/81 (2%) Frame = +1 Query: 316 SELKSCTRNFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLD-SFQGHK 492 S LK + +LGEG +G V++ V TG IVA+KK++LD + +G Sbjct: 14 SGLKDQFDRYNRMDILGEGTYGVVYRA---------VDRATGQIVALKKVRLDRTDEGIP 64 Query: 493 EW-LAEVNYLGQLSHPNLVKL 552 + L EV+ L ++ HPN+V L Sbjct: 65 QTALREVSILQEIHHPNIVNL 85
>CDPK2_PLAF7 (Q8ICR0) Calcium-dependent protein kinase 2 (EC 2.7.11.1) (PfCDPK2)| Length = 508 Score = 40.8 bits (94), Expect = 0.003 Identities = 21/67 (31%), Positives = 34/67 (50%) Frame = +1 Query: 352 DSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEWLAEVNYLGQLS 531 D LG+G +G V+KG + T + A+K+ K D + + E+ + +L Sbjct: 74 DEKLGQGTYGCVYKG---------IDKVTNQLYAIKEEKKDRLKNINRFFQEIEIMKKLD 124 Query: 532 HPNLVKL 552 HPN+VKL Sbjct: 125 HPNIVKL 131
>TAOK3_MOUSE (Q8BYC6) Serine/threonine-protein kinase TAO3 (EC 2.7.11.1)| (Thousand and one amino acid protein 3) Length = 898 Score = 40.8 bits (94), Expect = 0.003 Identities = 23/66 (34%), Positives = 33/66 (50%), Gaps = 3/66 (4%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEW---LAEVNYLGQLS 531 +G G FG+V+ T +VAVKK+ Q H++W L EV +L QL Sbjct: 30 IGHGSFGAVYFA---------TNAHTNEVVAVKKMSYSGKQTHEKWQDILKEVKFLQQLK 80 Query: 532 HPNLVK 549 HPN ++ Sbjct: 81 HPNTIE 86
>CDPK2_PLAFK (O15865) Calcium-dependent protein kinase 2 (EC 2.7.11.1) (PfCDPK2)| Length = 512 Score = 40.8 bits (94), Expect = 0.003 Identities = 21/67 (31%), Positives = 34/67 (50%) Frame = +1 Query: 352 DSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEWLAEVNYLGQLS 531 D LG+G +G V+KG + T + A+K+ K D + + E+ + +L Sbjct: 74 DEKLGQGTYGCVYKG---------IDKVTNQLYAIKEEKKDRLKNINRFFQEIEIMKKLD 124 Query: 532 HPNLVKL 552 HPN+VKL Sbjct: 125 HPNIVKL 131
>TAOK3_RAT (Q53UA7) Serine/threonine-protein kinase TAO3 (EC 2.7.11.1)| (Thousand and one amino acid protein 3) (Jun kinase-inhibitory kinase) (JNK/SAPK-inhibitory kinase) (Axotomy-related gene 357 protein) Length = 898 Score = 40.4 bits (93), Expect = 0.003 Identities = 22/66 (33%), Positives = 33/66 (50%), Gaps = 3/66 (4%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEW---LAEVNYLGQLS 531 +G G FG+V+ T +VA+KK+ Q H++W L EV +L QL Sbjct: 30 IGHGSFGAVYFA---------TNAHTNEVVAIKKMSYSGKQTHEKWQDILKEVRFLQQLK 80 Query: 532 HPNLVK 549 HPN ++ Sbjct: 81 HPNTIE 86
>TAOK3_PONPY (Q5R4F3) Serine/threonine-protein kinase TAO3 (EC 2.7.11.1)| (Thousand and one amino acid protein 3) Length = 898 Score = 40.4 bits (93), Expect = 0.003 Identities = 22/66 (33%), Positives = 33/66 (50%), Gaps = 3/66 (4%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEW---LAEVNYLGQLS 531 +G G FG+V+ T +VA+KK+ Q H++W L EV +L QL Sbjct: 30 IGHGSFGAVYFA---------TNAHTNEVVAIKKMSYSGKQTHEKWQDILKEVKFLRQLK 80 Query: 532 HPNLVK 549 HPN ++ Sbjct: 81 HPNTIE 86
>TAOK3_HUMAN (Q9H2K8) Serine/threonine-protein kinase TAO3 (EC 2.7.11.1)| (Thousand and one amino acid protein 3) (Jun kinase-inhibitory kinase) (JNK/SAPK-inhibitory kinase) (Dendritic cell-derived protein kinase) (Cutaneous T-cell lymphoma tumor antigen H Length = 898 Score = 40.4 bits (93), Expect = 0.003 Identities = 22/66 (33%), Positives = 33/66 (50%), Gaps = 3/66 (4%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEW---LAEVNYLGQLS 531 +G G FG+V+ T +VA+KK+ Q H++W L EV +L QL Sbjct: 30 IGHGSFGAVYFA---------TNAHTSEVVAIKKMSYSGKQTHEKWQDILKEVKFLRQLK 80 Query: 532 HPNLVK 549 HPN ++ Sbjct: 81 HPNTIE 86
>CDK7_MOUSE (Q03147) Cell division protein kinase 7 (EC 2.7.11.22) (EC| 2.7.11.23) (CDK-activating kinase) (CAK) (TFIIH basal transcription factor complex kinase subunit) (39 kDa protein kinase) (P39 Mo15) (Protein-tyrosine kinase MPK-7) (CR4 protein kinas Length = 346 Score = 40.4 bits (93), Expect = 0.003 Identities = 27/83 (32%), Positives = 40/83 (48%), Gaps = 5/83 (6%) Frame = +1 Query: 319 ELKSCTRNFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEW 498 ++KS + + LGEG F +V+K T IVA+KK+KL K+ Sbjct: 4 DVKSRAKRYEKLDFLGEGQFATVYKAR---------DKNTNQIVAIKKIKLGHRSEAKDG 54 Query: 499 -----LAEVNYLGQLSHPNLVKL 552 L E+ L +LSHPN++ L Sbjct: 55 INRTALREIKLLQELSHPNIIGL 77
>CDK7_HUMAN (P50613) Cell division protein kinase 7 (EC 2.7.11.22) (EC| 2.7.11.23) (CDK-activating kinase) (CAK) (TFIIH basal transcription factor complex kinase subunit) (39 kDa protein kinase) (P39 Mo15) (STK1) (CAK1) Length = 346 Score = 40.4 bits (93), Expect = 0.003 Identities = 27/83 (32%), Positives = 40/83 (48%), Gaps = 5/83 (6%) Frame = +1 Query: 319 ELKSCTRNFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEW 498 ++KS + + LGEG F +V+K T IVA+KK+KL K+ Sbjct: 4 DVKSRAKRYEKLDFLGEGQFATVYKAR---------DKNTNQIVAIKKIKLGHRSEAKDG 54 Query: 499 -----LAEVNYLGQLSHPNLVKL 552 L E+ L +LSHPN++ L Sbjct: 55 INRTALREIKLLQELSHPNIIGL 77
>YP141_YEAST (Q03002) Putative serine/threonine-protein kinase YPL141C (EC| 2.7.11.1) Length = 865 Score = 40.0 bits (92), Expect = 0.004 Identities = 29/73 (39%), Positives = 38/73 (52%), Gaps = 7/73 (9%) Frame = +1 Query: 355 SLLGEGGFGSVFKGWIDERTFTPVKPGTGMI---VAVKKLKLDS----FQGHKEWLAEVN 513 S LGEG FG V GW + F+ T VA+K +K DS ++ + E+N Sbjct: 45 STLGEGEFGKVKLGW--PKNFSNSSNSTFDFPKQVAIKLIKRDSISNDYRKEVKIYREIN 102 Query: 514 YLGQLSHPNLVKL 552 L LSHPN+VKL Sbjct: 103 ALKHLSHPNIVKL 115
>PHO85_YEAST (P17157) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 305 Score = 40.0 bits (92), Expect = 0.004 Identities = 24/76 (31%), Positives = 42/76 (55%), Gaps = 1/76 (1%) Frame = +1 Query: 328 SCTRNFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEW-LA 504 S + F+ LG G + +V+KG + TG+ VA+K++KLDS +G + Sbjct: 2 SSSSQFKQLEKLGNGTYATVYKG---------LNKTTGVYVALKEVKLDSEEGTPSTAIR 52 Query: 505 EVNYLGQLSHPNLVKL 552 E++ + +L H N+V+L Sbjct: 53 EISLMKELKHENIVRL 68
>CDK2_MOUSE (P97377) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 346 Score = 40.0 bits (92), Expect = 0.004 Identities = 26/73 (35%), Positives = 42/73 (57%), Gaps = 2/73 (2%) Frame = +1 Query: 340 NFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDS-FQGHKEW-LAEVN 513 NF+ +GEG +G V+K TG +VA+KK++LD+ +G + E++ Sbjct: 3 NFQKVEKIGEGTYGVVYKA---------KNKLTGEVVALKKIRLDTETEGVPSTAIREIS 53 Query: 514 YLGQLSHPNLVKL 552 L +L+HPN+VKL Sbjct: 54 LLKELNHPNIVKL 66
>CDC2_RAT (P39951) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 40.0 bits (92), Expect = 0.004 Identities = 26/66 (39%), Positives = 39/66 (59%), Gaps = 2/66 (3%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQG--HKEWLAEVNYLGQLSH 534 +GEG +G V+KG RT TG IVA+KK++L+S + + E++ L +L H Sbjct: 10 IGEGTYGVVYKG--RHRT-------TGQIVAMKKIRLESEEEGVPSTAIREISLLKELRH 60 Query: 535 PNLVKL 552 PN+V L Sbjct: 61 PNIVSL 66
>CDK2_RAT (Q63699) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 40.0 bits (92), Expect = 0.004 Identities = 26/73 (35%), Positives = 42/73 (57%), Gaps = 2/73 (2%) Frame = +1 Query: 340 NFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDS-FQGHKEW-LAEVN 513 NF+ +GEG +G V+K TG +VA+KK++LD+ +G + E++ Sbjct: 3 NFQKVEKIGEGTYGVVYKA---------KNKLTGEVVALKKIRLDTETEGVPSTAIREIS 53 Query: 514 YLGQLSHPNLVKL 552 L +L+HPN+VKL Sbjct: 54 LLKELNHPNIVKL 66
>CDK2_MESAU (P48963) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 40.0 bits (92), Expect = 0.004 Identities = 26/73 (35%), Positives = 42/73 (57%), Gaps = 2/73 (2%) Frame = +1 Query: 340 NFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDS-FQGHKEW-LAEVN 513 NF+ +GEG +G V+K TG +VA+KK++LD+ +G + E++ Sbjct: 3 NFQKVEKIGEGTYGVVYKA---------KNKLTGEVVALKKIRLDTETEGVPSTAIREIS 53 Query: 514 YLGQLSHPNLVKL 552 L +L+HPN+VKL Sbjct: 54 LLKELNHPNIVKL 66
>CDK2_CRIGR (O55076) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 40.0 bits (92), Expect = 0.004 Identities = 26/73 (35%), Positives = 42/73 (57%), Gaps = 2/73 (2%) Frame = +1 Query: 340 NFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDS-FQGHKEW-LAEVN 513 NF+ +GEG +G V+K TG +VA+KK++LD+ +G + E++ Sbjct: 3 NFQKVEKIGEGTYGVVYKA---------KNKLTGEVVALKKIRLDTETEGVPSTAIREIS 53 Query: 514 YLGQLSHPNLVKL 552 L +L+HPN+VKL Sbjct: 54 LLKELNHPNIVKL 66
>CDK2_BOVIN (Q5E9Y0) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 40.0 bits (92), Expect = 0.004 Identities = 26/73 (35%), Positives = 42/73 (57%), Gaps = 2/73 (2%) Frame = +1 Query: 340 NFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDS-FQGHKEW-LAEVN 513 NF+ +GEG +G V+K TG +VA+KK++LD+ +G + E++ Sbjct: 3 NFQKVEKIGEGTYGVVYKA---------KNKLTGEVVALKKIRLDTETEGVPSTAIREIS 53 Query: 514 YLGQLSHPNLVKL 552 L +L+HPN+VKL Sbjct: 54 LLKELNHPNIVKL 66
>CDC2_RANDY (Q9W739) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) Length = 302 Score = 40.0 bits (92), Expect = 0.004 Identities = 24/66 (36%), Positives = 38/66 (57%), Gaps = 2/66 (3%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQG--HKEWLAEVNYLGQLSH 534 +GEG +G V+KG V TG IVA+KK++L++ + + E++ L +L H Sbjct: 10 IGEGTYGVVYKG---------VHKATGQIVAMKKIRLENEEEGVPSTAIREISLLKELQH 60 Query: 535 PNLVKL 552 PN+V L Sbjct: 61 PNIVCL 66
>CDC2_ORYLU (Q9DG98) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 40.0 bits (92), Expect = 0.004 Identities = 25/66 (37%), Positives = 38/66 (57%), Gaps = 2/66 (3%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEWLA--EVNYLGQLSH 534 +GEG +G V+KG TG +VA+KK++L+S + A EV+ L +L H Sbjct: 10 IGEGTYGVVYKGR---------HKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQELKH 60 Query: 535 PNLVKL 552 PN+V+L Sbjct: 61 PNVVRL 66
>CDC2_ORYLA (Q9DGD3) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 40.0 bits (92), Expect = 0.004 Identities = 25/66 (37%), Positives = 38/66 (57%), Gaps = 2/66 (3%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEWLA--EVNYLGQLSH 534 +GEG +G V+KG TG +VA+KK++L+S + A EV+ L +L H Sbjct: 10 IGEGTYGVVYKGR---------HKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQELKH 60 Query: 535 PNLVKL 552 PN+V+L Sbjct: 61 PNVVRL 66
>CDC2_ORYJA (Q9DGA2) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 40.0 bits (92), Expect = 0.004 Identities = 25/66 (37%), Positives = 38/66 (57%), Gaps = 2/66 (3%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEWLA--EVNYLGQLSH 534 +GEG +G V+KG TG +VA+KK++L+S + A EV+ L +L H Sbjct: 10 IGEGTYGVVYKGR---------HKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQELKH 60 Query: 535 PNLVKL 552 PN+V+L Sbjct: 61 PNVVRL 66
>CDC2_ORYCU (Q9DGA5) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 40.0 bits (92), Expect = 0.004 Identities = 25/66 (37%), Positives = 38/66 (57%), Gaps = 2/66 (3%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEWLA--EVNYLGQLSH 534 +GEG +G V+KG TG +VA+KK++L+S + A EV+ L +L H Sbjct: 10 IGEGTYGVVYKGR---------HKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQELKH 60 Query: 535 PNLVKL 552 PN+V+L Sbjct: 61 PNVVRL 66
>CDC2_CARAU (P51958) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 302 Score = 40.0 bits (92), Expect = 0.004 Identities = 26/66 (39%), Positives = 40/66 (60%), Gaps = 2/66 (3%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEWLA--EVNYLGQLSH 534 +GEG +G V+KG R T TG +VA+KK++L+S + A E++ L +L H Sbjct: 10 IGEGTYGVVYKG----RNKT-----TGQVVAMKKIRLESEEEGVPSTAVREISLLKELQH 60 Query: 535 PNLVKL 552 PN+V+L Sbjct: 61 PNVVRL 66
>CDK2_HUMAN (P24941) Cell division protein kinase 2 (EC 2.7.11.22) (p33 protein| kinase) Length = 298 Score = 39.7 bits (91), Expect = 0.006 Identities = 26/73 (35%), Positives = 42/73 (57%), Gaps = 2/73 (2%) Frame = +1 Query: 340 NFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDS-FQGHKEW-LAEVN 513 NF+ +GEG +G V+K TG +VA+KK++LD+ +G + E++ Sbjct: 3 NFQKVEKIGEGTYGVVYKAR---------NKLTGEVVALKKIRLDTETEGVPSTAIREIS 53 Query: 514 YLGQLSHPNLVKL 552 L +L+HPN+VKL Sbjct: 54 LLKELNHPNIVKL 66
>KYK2_DICDI (P18161) Tyrosine-protein kinase 2 (EC 2.7.10.2) (Fragment)| Length = 410 Score = 39.7 bits (91), Expect = 0.006 Identities = 31/99 (31%), Positives = 48/99 (48%), Gaps = 11/99 (11%) Frame = +1 Query: 283 LQSSNLRKFTFSELKSCT--RNFRTD-------SLLGEGGFGSVFKGWIDERTFTPVKPG 435 ++S ++K F ELKS R + D +GEG F V++GW Sbjct: 79 IESEKIKKTKFEELKSILGEREYIIDINDIQFIQKVGEGAFSEVWEGW-----------W 127 Query: 436 TGMIVAVKKLKL--DSFQGHKEWLAEVNYLGQLSHPNLV 546 G+ VA+KKLK+ D Q + ++ EV L + +H N+V Sbjct: 128 KGIHVAIKKLKIIGDEEQFKERFIREVQNLKKGNHQNIV 166
>EPHB3_HUMAN (P54753) Ephrin type-B receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor HEK-2) Length = 998 Score = 39.7 bits (91), Expect = 0.006 Identities = 25/93 (26%), Positives = 48/93 (51%), Gaps = 11/93 (11%) Frame = +1 Query: 307 FTFSELKSCTRNF---------RTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMI-VAV 456 FT+ + R F + + ++G G FG V +G + + PG + VA+ Sbjct: 612 FTYEDPNEAVREFAKEIDVSCVKIEEVIGAGEFGEVCRGRLKQ-------PGRREVFVAI 664 Query: 457 KKLKLD-SFQGHKEWLAEVNYLGQLSHPNLVKL 552 K LK+ + + +++L+E + +GQ HPN+++L Sbjct: 665 KTLKVGYTERQRRDFLSEASIMGQFDHPNIIRL 697
>PHO85_CANGA (Q6FKD4) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 302 Score = 39.7 bits (91), Expect = 0.006 Identities = 23/71 (32%), Positives = 40/71 (56%), Gaps = 1/71 (1%) Frame = +1 Query: 343 FRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEW-LAEVNYL 519 F+ LG G + +V+KG + TG+ VA+K++KLDS +G + E++ + Sbjct: 6 FKQLEKLGNGTYATVYKG---------LNKSTGVYVALKEVKLDSEEGTPSTAIREISLM 56 Query: 520 GQLSHPNLVKL 552 +L H N+V+L Sbjct: 57 KELKHDNIVRL 67
>FAK2_MOUSE (Q9QVP9) Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal| adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinas Length = 1009 Score = 39.7 bits (91), Expect = 0.006 Identities = 27/66 (40%), Positives = 39/66 (59%), Gaps = 1/66 (1%) Frame = +1 Query: 358 LLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKE-WLAEVNYLGQLSH 534 +LGEG FG V++G +T K G + VAVK K D Q +KE +++E + L H Sbjct: 430 ILGEGFFGEVYEG-----VYTNHK-GEKINVAVKTCKKDCTQDNKEKFMSEAVIMKNLDH 483 Query: 535 PNLVKL 552 P++VKL Sbjct: 484 PHIVKL 489
>EPHA3_BRARE (O13146) Ephrin type-A receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ZEK1) (EPH-like kinase 1) Length = 981 Score = 39.3 bits (90), Expect = 0.007 Identities = 25/72 (34%), Positives = 39/72 (54%), Gaps = 1/72 (1%) Frame = +1 Query: 340 NFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLD-SFQGHKEWLAEVNY 516 N R + ++G G FG V G R P K + VA+K LK S +++L+E + Sbjct: 625 NIRIERVIGAGEFGEVCSG----RLRLPSK--REIQVAIKSLKAGYSEHQRRDFLSEASI 678 Query: 517 LGQLSHPNLVKL 552 +GQ HPN+++L Sbjct: 679 MGQFDHPNIIRL 690
>PHO85_ASHGO (Q751E8) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 303 Score = 39.3 bits (90), Expect = 0.007 Identities = 23/71 (32%), Positives = 40/71 (56%), Gaps = 1/71 (1%) Frame = +1 Query: 343 FRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEW-LAEVNYL 519 F+ LG G + +V+KG + TG+ VA+K++KLDS +G + E++ + Sbjct: 9 FKQLERLGNGTYATVYKG---------LNKTTGLYVALKEVKLDSEEGTPSTAIREISLM 59 Query: 520 GQLSHPNLVKL 552 +L H N+V+L Sbjct: 60 KELKHENIVRL 70
>CDC2_DICDI (P34112) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) Length = 296 Score = 38.9 bits (89), Expect = 0.010 Identities = 22/64 (34%), Positives = 35/64 (54%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEWLAEVNYLGQLSHPN 540 LGEG +G V+K + TG +VA+KK++L+ L E++ L ++ HPN Sbjct: 16 LGEGTYGKVYKA---------KEKATGRMVALKKIRLEDDGVPSTALREISLLKEVPHPN 66 Query: 541 LVKL 552 +V L Sbjct: 67 VVSL 70
>NTRK3_PIG (P24786) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (GP145-TrkC) (Trk-C) Length = 825 Score = 38.5 bits (88), Expect = 0.013 Identities = 25/63 (39%), Positives = 32/63 (50%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEWLAEVNYLGQLSHPN 540 LGEG FG VF + T VK M+VAVK LK + K++ E L L H + Sbjct: 544 LGEGAFGKVFLAECYNLSPTKVK----MLVAVKALKDPTLAARKDFQREAELLTNLQHEH 599 Query: 541 LVK 549 +VK Sbjct: 600 IVK 602
>CDK3_HUMAN (Q00526) Cell division protein kinase 3 (EC 2.7.11.22)| Length = 305 Score = 38.5 bits (88), Expect = 0.013 Identities = 25/72 (34%), Positives = 40/72 (55%), Gaps = 2/72 (2%) Frame = +1 Query: 343 FRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLD-SFQGHKEW-LAEVNY 516 F+ +GEG +G V+K E TG +VA+KK++LD +G + E++ Sbjct: 4 FQKVEKIGEGTYGVVYKAKNRE---------TGQLVALKKIRLDLEMEGVPSTAIREISL 54 Query: 517 LGQLSHPNLVKL 552 L +L HPN+V+L Sbjct: 55 LKELKHPNIVRL 66
>E2AK1_SCHPO (O13889) Eukaryotic translation initiation factor 2-alpha kinase 1| (EC 2.7.11.1) (Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase) (Heme-regulated inhibitor 1) Length = 704 Score = 38.5 bits (88), Expect = 0.013 Identities = 29/91 (31%), Positives = 42/91 (46%), Gaps = 2/91 (2%) Frame = +1 Query: 283 LQSSNLRKFTFSELKSCTRNFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKK 462 L SN F + +F LLG+GG+GSV+K F G+ A+KK Sbjct: 204 LSFSNFDSFPTVQRSRYASDFEELELLGKGGYGSVYKA---RNKF------DGVEYALKK 254 Query: 463 --LKLDSFQGHKEWLAEVNYLGQLSHPNLVK 549 L+L SF E L +L+HPN+++ Sbjct: 255 IPLRLRSFSTSSNIFRESRTLARLNHPNVIR 285
>CDC2_HUMAN (P06493) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 38.5 bits (88), Expect = 0.013 Identities = 26/66 (39%), Positives = 39/66 (59%), Gaps = 2/66 (3%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEWLA--EVNYLGQLSH 534 +GEG +G V+KG R T TG +VA+KK++L+S + A E++ L +L H Sbjct: 10 IGEGTYGVVYKG----RHKT-----TGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60 Query: 535 PNLVKL 552 PN+V L Sbjct: 61 PNIVSL 66
>CDC2_BOVIN (P48734) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 38.5 bits (88), Expect = 0.013 Identities = 26/66 (39%), Positives = 39/66 (59%), Gaps = 2/66 (3%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEWLA--EVNYLGQLSH 534 +GEG +G V+KG R T TG +VA+KK++L+S + A E++ L +L H Sbjct: 10 IGEGTYGVVYKG----RHKT-----TGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60 Query: 535 PNLVKL 552 PN+V L Sbjct: 61 PNIVSL 66
>SLK_MOUSE (O54988) STE20-like serine/threonine-protein kinase (EC 2.7.11.1)| (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (mSLK) (Serine/threonine-protein kinase 2) (STE20-related kinase SMAK) (Etk4) Length = 1233 Score = 38.1 bits (87), Expect = 0.017 Identities = 20/64 (31%), Positives = 33/64 (51%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEWLAEVNYLGQLSHPN 540 LG+G FG V+K E T ++ A K + S + ++++ E++ L HPN Sbjct: 40 LGDGAFGKVYKAQNKE---------TNVLAAAKVIDTKSEEELEDYMVEIDILASCDHPN 90 Query: 541 LVKL 552 +VKL Sbjct: 91 IVKL 94
>EPHA3_MOUSE (P29319) Ephrin type-A receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ETK1) (MEK4) Length = 983 Score = 38.1 bits (87), Expect = 0.017 Identities = 24/72 (33%), Positives = 38/72 (52%), Gaps = 1/72 (1%) Frame = +1 Query: 340 NFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLD-SFQGHKEWLAEVNY 516 N D ++G G FG V G R P K VA+K LK+ + + +++L E + Sbjct: 620 NISIDKVVGAGEFGEVCSG----RLKLPSKKEIS--VAIKTLKVGYTEKQRRDFLGEASI 673 Query: 517 LGQLSHPNLVKL 552 +GQ HPN+++L Sbjct: 674 MGQFDHPNIIRL 685
>EPHA3_HUMAN (P29320) Ephrin type-A receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ETK1) (HEK) (HEK4) Length = 983 Score = 38.1 bits (87), Expect = 0.017 Identities = 24/72 (33%), Positives = 38/72 (52%), Gaps = 1/72 (1%) Frame = +1 Query: 340 NFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLD-SFQGHKEWLAEVNY 516 N D ++G G FG V G R P K VA+K LK+ + + +++L E + Sbjct: 620 NISIDKVVGAGEFGEVCSG----RLKLPSKKEIS--VAIKTLKVGYTEKQRRDFLGEASI 673 Query: 517 LGQLSHPNLVKL 552 +GQ HPN+++L Sbjct: 674 MGQFDHPNIIRL 685
>EPHA2_HUMAN (P29317) Ephrin type-A receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) Length = 976 Score = 38.1 bits (87), Expect = 0.017 Identities = 26/84 (30%), Positives = 40/84 (47%), Gaps = 1/84 (1%) Frame = +1 Query: 304 KFTFSELKSCTRNFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQ 483 KFT SC ++G G FG V+KG + + P VA+K LK + Sbjct: 603 KFTTEIHPSCVTR---QKVIGAGEFGEVYKGMLKTSSGKKEVP-----VAIKTLKAGYTE 654 Query: 484 GHK-EWLAEVNYLGQLSHPNLVKL 552 + ++L E +GQ SH N+++L Sbjct: 655 KQRVDFLGEAGIMGQFSHHNIIRL 678
>SLK_CAVPO (O55092) STE20-like serine/threonine-protein kinase (EC 2.7.11.1)| (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) Length = 1231 Score = 38.1 bits (87), Expect = 0.017 Identities = 20/64 (31%), Positives = 33/64 (51%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEWLAEVNYLGQLSHPN 540 LG+G FG V+K E T ++ A K + S + ++++ E++ L HPN Sbjct: 40 LGDGAFGKVYKAQNKE---------TNVLAAAKVIDTKSEEELEDYMVEIDILASCDHPN 90 Query: 541 LVKL 552 +VKL Sbjct: 91 IVKL 94
>RET_MOUSE (P35546) Proto-oncogene tyrosine-protein kinase receptor ret| precursor (EC 2.7.10.1) (C-ret) Length = 1115 Score = 38.1 bits (87), Expect = 0.017 Identities = 28/74 (37%), Positives = 40/74 (54%), Gaps = 2/74 (2%) Frame = +1 Query: 337 RNFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMI-VAVKKLKLDSFQGH-KEWLAEV 510 +N LGEG FG V K T +K G VAVK LK ++ Q ++ L+E Sbjct: 723 KNLVLGKTLGEGEFGKVVKA-----TAFRLKGRAGYTTVAVKMLKENASQSELRDLLSEF 777 Query: 511 NYLGQLSHPNLVKL 552 N L Q++HP+++KL Sbjct: 778 NLLKQVNHPHVIKL 791
>SLK_RAT (O08815) STE20-like serine/threonine-protein kinase (EC 2.7.11.1)| (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) Length = 1206 Score = 38.1 bits (87), Expect = 0.017 Identities = 20/64 (31%), Positives = 33/64 (51%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEWLAEVNYLGQLSHPN 540 LG+G FG V+K E T ++ A K + S + ++++ E++ L HPN Sbjct: 40 LGDGAFGKVYKAQNKE---------TNVLAAAKVIDTKSEEELEDYMVEIDILASCDHPN 90 Query: 541 LVKL 552 +VKL Sbjct: 91 IVKL 94
>CDK7_RAT (P51952) Cell division protein kinase 7 (EC 2.7.11.22) (EC| 2.7.11.23) (CDK-activating kinase) (CAK) (TFIIH basal transcription factor complex kinase subunit) (39 protein kinase) (P39 Mo15) (Fragment) Length = 329 Score = 38.1 bits (87), Expect = 0.017 Identities = 28/77 (36%), Positives = 38/77 (49%), Gaps = 5/77 (6%) Frame = +1 Query: 337 RNFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEW-----L 501 RN + D LGEG F +V+K T IVA+KK+KL K+ L Sbjct: 3 RNEKLD-FLGEGQFATVYKAR---------DKNTNQIVAIKKIKLGHRSEAKDGINRTAL 52 Query: 502 AEVNYLGQLSHPNLVKL 552 E+ L +LSHPN++ L Sbjct: 53 REIKLLQELSHPNIIGL 69
>IRAK1_HUMAN (P51617) Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1)| (IRAK-1) Length = 712 Score = 38.1 bits (87), Expect = 0.017 Identities = 25/80 (31%), Positives = 38/80 (47%), Gaps = 4/80 (5%) Frame = +1 Query: 319 ELKSCTRNFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLK----LDSFQG 486 E+ T NF + +GEGGFG V++ + + AVK+LK L+ Sbjct: 204 EISRGTHNFSEELKIGEGGFGCVYRAVM-----------RNTVYAVKRLKENADLEWTAV 252 Query: 487 HKEWLAEVNYLGQLSHPNLV 546 + +L EV L + HPN+V Sbjct: 253 KQSFLTEVEQLSRFRHPNIV 272
>EPHA3_RAT (O08680) Ephrin type-A receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor REK4) (TYRO-4) Length = 984 Score = 38.1 bits (87), Expect = 0.017 Identities = 24/72 (33%), Positives = 38/72 (52%), Gaps = 1/72 (1%) Frame = +1 Query: 340 NFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLD-SFQGHKEWLAEVNY 516 N D ++G G FG V G R P K VA+K LK+ + + +++L E + Sbjct: 621 NIAIDKVVGAGEFGEVCSG----RLKLPSKKEIS--VAIKTLKVGYTEKQRRDFLGEASI 674 Query: 517 LGQLSHPNLVKL 552 +GQ HPN+++L Sbjct: 675 MGQFDHPNIIRL 686
>ROS_HUMAN (P08922) Proto-oncogene tyrosine-protein kinase ROS precursor (EC| 2.7.10.1) (c-ros-1) Length = 2347 Score = 38.1 bits (87), Expect = 0.017 Identities = 26/66 (39%), Positives = 37/66 (56%), Gaps = 2/66 (3%) Frame = +1 Query: 358 LLGEGGFGSVFKGWIDERTFTPVKPGTGMI-VAVKKLKLDSFQGHK-EWLAEVNYLGQLS 531 LLG G FG V++G + G+G I VAVK LK S K E+L E + + + + Sbjct: 1950 LLGSGAFGEVYEG----TAVDILGVGSGEIKVAVKTLKKGSTDQEKIEFLKEAHLMSKFN 2005 Query: 532 HPNLVK 549 HPN++K Sbjct: 2006 HPNILK 2011
>EPHB4_MOUSE (P54761) Ephrin type-B receptor 4 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor MDK-2) (Developmental kinase 2) (Tyrosine kinase MYK-1) Length = 987 Score = 38.1 bits (87), Expect = 0.017 Identities = 27/92 (29%), Positives = 46/92 (50%), Gaps = 10/92 (10%) Frame = +1 Query: 307 FTFSELKSCTRNF---------RTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVK 459 FT+ + R F + + ++G G FG V +G R P K + VA+K Sbjct: 594 FTYEDPNEAVREFAKEIDVSYVKIEEVIGAGEFGEVCRG----RLKAPGKKES--CVAIK 647 Query: 460 KLKLD-SFQGHKEWLAEVNYLGQLSHPNLVKL 552 LK + + +E+L+E + +GQ HPN+++L Sbjct: 648 TLKGGYTERQRREFLSEASIMGQFEHPNIIRL 679
>EPHB4_HUMAN (P54760) Ephrin type-B receptor 4 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor HTK) Length = 987 Score = 38.1 bits (87), Expect = 0.017 Identities = 27/92 (29%), Positives = 46/92 (50%), Gaps = 10/92 (10%) Frame = +1 Query: 307 FTFSELKSCTRNF---------RTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVK 459 FT+ + R F + + ++G G FG V +G R P K + VA+K Sbjct: 594 FTYEDPNEAVREFAKEIDVSYVKIEEVIGAGEFGEVCRG----RLKAPGKKES--CVAIK 647 Query: 460 KLKLD-SFQGHKEWLAEVNYLGQLSHPNLVKL 552 LK + + +E+L+E + +GQ HPN+++L Sbjct: 648 TLKGGYTERQRREFLSEASIMGQFEHPNIIRL 679
>EPHB3_XENLA (Q91735) Ephrin type-B receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor TCK) Length = 974 Score = 38.1 bits (87), Expect = 0.017 Identities = 24/92 (26%), Positives = 44/92 (47%), Gaps = 10/92 (10%) Frame = +1 Query: 307 FTFSELKSCTRNF---------RTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVK 459 FT+ + R+F + + ++G G FG V +G + + VA+K Sbjct: 588 FTYEDPNEAVRDFAKEIDISCVKIEEVIGAGEFGEVCRGKLKQAGRRE------QFVAIK 641 Query: 460 KLKLD-SFQGHKEWLAEVNYLGQLSHPNLVKL 552 LK + Q +++L E + +GQ HPN+++L Sbjct: 642 TLKAGYTEQQRRDFLGEASIMGQFDHPNIIRL 673
>EPHB3_MOUSE (P54754) Ephrin type-B receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor MDK-5) (Developmental kinase 5) (SEK-4) Length = 993 Score = 38.1 bits (87), Expect = 0.017 Identities = 25/93 (26%), Positives = 47/93 (50%), Gaps = 11/93 (11%) Frame = +1 Query: 307 FTFSELKSCTRNF---------RTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMI-VAV 456 FT+ + R F + + ++G G FG V +G + PG + VA+ Sbjct: 607 FTYEDPNEAVREFAKEIDVSCVKIEEVIGAGEFGEVCRGRLK-------LPGRREVFVAI 659 Query: 457 KKLKLD-SFQGHKEWLAEVNYLGQLSHPNLVKL 552 K LK+ + + +++L+E + +GQ HPN+++L Sbjct: 660 KTLKVGYTERQRRDFLSEASIMGQFDHPNIIRL 692
>SLK_HUMAN (Q9H2G2) STE20-like serine/threonine-protein kinase (EC 2.7.11.1)| (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (hSLK) (Serine/threonine-protein kinase 2) (CTCL tumor antigen se20-9) Length = 1235 Score = 38.1 bits (87), Expect = 0.017 Identities = 20/64 (31%), Positives = 33/64 (51%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEWLAEVNYLGQLSHPN 540 LG+G FG V+K E T ++ A K + S + ++++ E++ L HPN Sbjct: 40 LGDGAFGKVYKAQNKE---------TSVLAAAKVIDTKSEEELEDYMVEIDILASCDHPN 90 Query: 541 LVKL 552 +VKL Sbjct: 91 IVKL 94
>PHO85_YARLI (Q6C7U8) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 294 Score = 38.1 bits (87), Expect = 0.017 Identities = 24/65 (36%), Positives = 38/65 (58%), Gaps = 1/65 (1%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEW-LAEVNYLGQLSHP 537 LGEG + +V+KG RT TG +VA+K++ LDS +G + E++ + +L H Sbjct: 13 LGEGTYATVYKG--RNRT-------TGQLVALKEINLDSEEGTPSTAIREISLMKELKHE 63 Query: 538 NLVKL 552 N+V L Sbjct: 64 NIVTL 68
>CDC2_MOUSE (P11440) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 38.1 bits (87), Expect = 0.017 Identities = 25/66 (37%), Positives = 38/66 (57%), Gaps = 2/66 (3%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQG--HKEWLAEVNYLGQLSH 534 +GEG +G V+KG R TG IVA+KK++L+S + + E++ L +L H Sbjct: 10 IGEGTYGVVYKG--RHRV-------TGQIVAMKKIRLESEEEGVPSTAIREISLLKELRH 60 Query: 535 PNLVKL 552 PN+V L Sbjct: 61 PNIVSL 66
>CDK7_CARAU (P51953) Cell division protein kinase 7 (EC 2.7.11.22) (EC| 2.7.11.23) (40 kDa protein kinase) (P40 MO15) (CDC2/CDK2,4-activating kinase) Length = 344 Score = 37.7 bits (86), Expect = 0.022 Identities = 27/83 (32%), Positives = 43/83 (51%), Gaps = 5/83 (6%) Frame = +1 Query: 319 ELKSCTRNFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEW 498 ++KS + + LGEG F +V+K ++T T IVA+KK+K+ K+ Sbjct: 4 DVKSRAKLYEKLDFLGEGQFATVYKA--RDKT-------TNTIVAIKKIKVGHRTEAKDG 54 Query: 499 -----LAEVNYLGQLSHPNLVKL 552 L E+ L +LSHPN++ L Sbjct: 55 INRTALREIKLLQELSHPNIIGL 77
>EPHA1_HUMAN (P21709) Ephrin type-A receptor 1 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH) Length = 976 Score = 37.7 bits (86), Expect = 0.022 Identities = 24/69 (34%), Positives = 38/69 (55%), Gaps = 2/69 (2%) Frame = +1 Query: 352 DSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEW--LAEVNYLGQ 525 D+++GEG FG V++G + + VA+K LK D+ G + W L E +GQ Sbjct: 627 DTVIGEGEFGEVYRGTL------RLPSQDCKTVAIKTLK-DTSPGGQWWNFLREATIMGQ 679 Query: 526 LSHPNLVKL 552 SHP+++ L Sbjct: 680 FSHPHILHL 688
>IRAK3_HUMAN (Q9Y616) Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1)| (IRAK-3) (IL-1 receptor-associated kinase M) (IRAK-M) Length = 596 Score = 37.7 bits (86), Expect = 0.022 Identities = 31/98 (31%), Positives = 46/98 (46%), Gaps = 4/98 (4%) Frame = +1 Query: 271 EKEILQSSNLRKFTFSELKSCTRNFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIV 450 EK +L S++ +F + TRNF D L+GEG V++ I T+ Sbjct: 144 EKGVLLKSSI---SFQNIIEGTRNFHKDFLIGEGEIFEVYRVEIQNLTY----------- 189 Query: 451 AVKKLKLD-SFQGHKEW---LAEVNYLGQLSHPNLVKL 552 AVK K + Q K W L+E+ L HPN+++L Sbjct: 190 AVKLFKQEKKMQCKKHWKRFLSELEVLLLFHHPNILEL 227
>CDK7_XENLA (P20911) Cell division protein kinase 7 (EC 2.7.11.22) (EC| 2.7.11.23) (40 kDa protein kinase) (P40 MO15) (CDC2/CDK2,4-activating kinase) Length = 352 Score = 37.7 bits (86), Expect = 0.022 Identities = 26/83 (31%), Positives = 43/83 (51%), Gaps = 5/83 (6%) Frame = +1 Query: 319 ELKSCTRNFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKL----DSFQG 486 +++S + + LGEG F +V+K T IVA+KK+KL ++ G Sbjct: 10 DVRSRAKQYEKLDFLGEGQFATVYKAR---------DKNTDRIVAIKKIKLGHRAEANDG 60 Query: 487 -HKEWLAEVNYLGQLSHPNLVKL 552 ++ L E+ L +LSHPN++ L Sbjct: 61 INRTALREIKLLQELSHPNIIGL 83
>PHO85_KLULA (Q92241) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 304 Score = 37.7 bits (86), Expect = 0.022 Identities = 22/71 (30%), Positives = 40/71 (56%), Gaps = 1/71 (1%) Frame = +1 Query: 343 FRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEW-LAEVNYL 519 F+ +G G + +V+KG + TG+ VA+K++KLDS +G + E++ + Sbjct: 7 FKQLEKVGNGTYATVYKG---------LNKTTGVYVALKEVKLDSEEGTPSTAIREISLM 57 Query: 520 GQLSHPNLVKL 552 +L H N+V+L Sbjct: 58 KELKHDNIVRL 68
>EPHA3_CHICK (P29318) Ephrin type-A receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ETK1) (CEK4) Length = 983 Score = 37.4 bits (85), Expect = 0.028 Identities = 24/72 (33%), Positives = 37/72 (51%), Gaps = 1/72 (1%) Frame = +1 Query: 340 NFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLD-SFQGHKEWLAEVNY 516 N D ++G G FG V G R P K VA+K LK + + +++L E + Sbjct: 620 NISIDKVVGAGEFGEVCSG----RLKLPSKKEIS--VAIKTLKAGYTEKQRRDFLGEASI 673 Query: 517 LGQLSHPNLVKL 552 +GQ HPN+++L Sbjct: 674 MGQFDHPNIIRL 685
>TAOK3_CHICK (Q9I9E0) Serine/threonine-protein kinase TAO3 (EC 2.7.11.1)| (Thousand and one amino acid protein 3) (Kinase from chicken) Length = 898 Score = 37.4 bits (85), Expect = 0.028 Identities = 21/66 (31%), Positives = 33/66 (50%), Gaps = 3/66 (4%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEW---LAEVNYLGQLS 531 +G G FG+V+ T +VAVKK+ Q +++W + EV +L QL Sbjct: 30 IGHGSFGAVYFA---------TNSHTNEVVAVKKMSYSGKQTNEKWQDIIKEVKFLQQLK 80 Query: 532 HPNLVK 549 HPN ++ Sbjct: 81 HPNTIE 86
>TAOK3_XENLA (Q6DD27) Serine/threonine-protein kinase TAO3 (EC 2.7.11.1)| (Thousand and one amino acid protein 3) Length = 896 Score = 37.4 bits (85), Expect = 0.028 Identities = 22/66 (33%), Positives = 33/66 (50%), Gaps = 3/66 (4%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEW---LAEVNYLGQLS 531 +G G FG+V+ T IVAVKK+ Q +++W + EV +L QL Sbjct: 30 IGHGSFGAVYFA---------TNSTTNEIVAVKKMSYSGKQMNEKWQDIIKEVKFLQQLK 80 Query: 532 HPNLVK 549 HPN ++ Sbjct: 81 HPNTIE 86
>PO2F2_HUMAN (P09086) POU domain, class 2, transcription factor 2| (Octamer-binding transcription factor 2) (Oct-2) (OTF-2) (Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2) Length = 478 Score = 37.4 bits (85), Expect = 0.028 Identities = 19/51 (37%), Positives = 28/51 (54%), Gaps = 4/51 (7%) Frame = -1 Query: 402 DPPLEDGAEAPLPEQAVSPEVPRATFQLT----EGELAEVGRLQDLLLAPG 262 DP + APLP Q P +P+A LT G++ ++ +LQ L+L PG Sbjct: 66 DPSGDSAPAAPLPPQPAQPHLPQAQLMLTGSQLAGDIQQLLQLQQLVLVPG 116
>EPHB3_CHICK (Q07498) Ephrin type-B receptor 3 (EC 2.7.10.1) (Tyrosine-protein| kinase receptor CEK10) (Fragment) Length = 988 Score = 37.4 bits (85), Expect = 0.028 Identities = 26/93 (27%), Positives = 46/93 (49%), Gaps = 11/93 (11%) Frame = +1 Query: 307 FTFSELKSCTRNF---------RTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMI-VAV 456 FT+ + R F + + ++G G FG V +G + PG I VA+ Sbjct: 602 FTYEDPNEAVREFAKEIDISCVKIEEVIGAGEFGEVCRGRLK-------LPGRREIFVAI 654 Query: 457 KKLKLD-SFQGHKEWLAEVNYLGQLSHPNLVKL 552 K LK+ + + +++L+E + +GQ HPN++ L Sbjct: 655 KTLKVGYTERQRRDFLSEASIMGQFDHPNIIHL 687
>CDC2_CHICK (P13863) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 37.4 bits (85), Expect = 0.028 Identities = 26/66 (39%), Positives = 39/66 (59%), Gaps = 2/66 (3%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEWLA--EVNYLGQLSH 534 +GEG +G V+KG R T TG +VA+KK++L+S + A E++ L +L H Sbjct: 10 IGEGTYGVVYKG----RHKT-----TGQVVAMKKIRLESEEEGVPSTAIREISLLKELHH 60 Query: 535 PNLVKL 552 PN+V L Sbjct: 61 PNIVCL 66
>CDK2_CARAU (P43450) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 37.0 bits (84), Expect = 0.037 Identities = 25/73 (34%), Positives = 41/73 (56%), Gaps = 2/73 (2%) Frame = +1 Query: 340 NFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDS-FQGHKEW-LAEVN 513 +F+ +GEG +G V+K TG VA+KK++LD+ +G + E++ Sbjct: 3 SFQKVEKIGEGTYGVVYKA---------KNKVTGETVALKKIRLDTETEGVPSTAIREIS 53 Query: 514 YLGQLSHPNLVKL 552 L +L+HPN+VKL Sbjct: 54 LLKELNHPNIVKL 66
>PEF1_SCHPO (O74456) Serine/threonine-protein kinase pef1 (EC 2.7.11.22)| (Cyclin-dependent kinase pef1) (PHO85 homolog) Length = 288 Score = 37.0 bits (84), Expect = 0.037 Identities = 23/72 (31%), Positives = 40/72 (55%), Gaps = 1/72 (1%) Frame = +1 Query: 340 NFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEW-LAEVNY 516 N++ LGEG + V+KG R TG IVA+K +++D+ +G + E++ Sbjct: 2 NYQRLEKLGEGTYAHVYKG--QNRV-------TGEIVALKVIRIDADEGTPSTAIREISL 52 Query: 517 LGQLSHPNLVKL 552 + +L HPN++ L Sbjct: 53 MKELRHPNIMSL 64
>LCK_MOUSE (P06240) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) Length = 508 Score = 37.0 bits (84), Expect = 0.037 Identities = 26/64 (40%), Positives = 32/64 (50%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEWLAEVNYLGQLSHPN 540 LG G FG V+ G+ + T VAVK LK S +LAE N + QL HP Sbjct: 250 LGAGQFGEVWMGYYNGHTK----------VAVKSLKQGSMSPDA-FLAEANLMKQLQHPR 298 Query: 541 LVKL 552 LV+L Sbjct: 299 LVRL 302
>FAK2_RAT (P70600) Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal| adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) Length = 1009 Score = 37.0 bits (84), Expect = 0.037 Identities = 26/66 (39%), Positives = 38/66 (57%), Gaps = 1/66 (1%) Frame = +1 Query: 358 LLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKE-WLAEVNYLGQLSH 534 +LGEG FG V++G +T K G + VAVK K D +KE +++E + L H Sbjct: 430 ILGEGFFGEVYEG-----VYTNHK-GEKINVAVKTCKKDCTLDNKEKFMSEAVIMKNLDH 483 Query: 535 PNLVKL 552 P++VKL Sbjct: 484 PHIVKL 489
>FAK2_HUMAN (Q14289) Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal| adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinas Length = 1009 Score = 37.0 bits (84), Expect = 0.037 Identities = 26/66 (39%), Positives = 38/66 (57%), Gaps = 1/66 (1%) Frame = +1 Query: 358 LLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKE-WLAEVNYLGQLSH 534 +LGEG FG V++G +T K G + VAVK K D +KE +++E + L H Sbjct: 430 ILGEGFFGEVYEG-----VYTNHK-GEKINVAVKTCKKDCTLDNKEKFMSEAVIMKNLDH 483 Query: 535 PNLVKL 552 P++VKL Sbjct: 484 PHIVKL 489
>PHO85_CANAL (Q9HGY5) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) (CaPHO85) Length = 326 Score = 37.0 bits (84), Expect = 0.037 Identities = 22/65 (33%), Positives = 36/65 (55%), Gaps = 1/65 (1%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEW-LAEVNYLGQLSHP 537 LGEG + +V+KG TG +VA+K++ LDS +G + E++ + +L H Sbjct: 14 LGEGTYATVYKG---------RNRATGALVALKEISLDSEEGTPSTAIREISLMKELDHE 64 Query: 538 NLVKL 552 N+V L Sbjct: 65 NIVTL 69
>M3K1_ARATH (O22040) Mitogen-activated protein kinase kinase kinase 1 (EC| 2.7.11.25) (Arabidospsis NPK1-related protein kinase 1) Length = 666 Score = 37.0 bits (84), Expect = 0.037 Identities = 24/72 (33%), Positives = 37/72 (51%), Gaps = 2/72 (2%) Frame = +1 Query: 340 NFRTDSLLGEGGFGSVFKGW-IDERTFTPVKPGTGMIVAVKKLKLDSFQGH-KEWLAEVN 513 ++R L+G G FG+V+ G +D VK +++A + Q H +E EV Sbjct: 68 SWRKGQLIGRGAFGTVYMGMNLDSGELLAVKQ---VLIAANFASKEKTQAHIQELEEEVK 124 Query: 514 YLGQLSHPNLVK 549 L LSHPN+V+ Sbjct: 125 LLKNLSHPNIVR 136
>M3K3_ARATH (O22042) Mitogen-activated protein kinase kinase kinase 3 (EC| 2.7.11.25) (Arabidospsis NPK1-related protein kinase 3) Length = 651 Score = 37.0 bits (84), Expect = 0.037 Identities = 24/71 (33%), Positives = 36/71 (50%), Gaps = 2/71 (2%) Frame = +1 Query: 343 FRTDSLLGEGGFGSVFKGW-IDERTFTPVKPGTGMIVAVKKLKLDSFQGH-KEWLAEVNY 516 +R L+G G FG V+ G +D +K +++A + QGH +E EV Sbjct: 68 WRKGELIGCGAFGRVYMGMNLDSGELLAIKQ---VLIAPSSASKEKTQGHIRELEEEVQL 124 Query: 517 LGQLSHPNLVK 549 L LSHPN+V+ Sbjct: 125 LKNLSHPNIVR 135
>CDC22_XENLA (P24033) Cell division control protein 2 homolog 2 (EC 2.7.11.22)| (EC 2.7.11.23) (p34 protein kinase 2) Length = 302 Score = 37.0 bits (84), Expect = 0.037 Identities = 23/66 (34%), Positives = 37/66 (56%), Gaps = 2/66 (3%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEWLA--EVNYLGQLSH 534 +GEG +G V+KG TG +VA+KK++L++ + A E++ L +L H Sbjct: 10 IGEGTYGVVYKGR---------HKATGQVVAMKKIRLENEEEGVPSTAIREISLLKELQH 60 Query: 535 PNLVKL 552 PN+V L Sbjct: 61 PNIVCL 66
>CDC21_XENLA (P35567) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| (EC 2.7.11.23) (p34 protein kinase 1) Length = 302 Score = 37.0 bits (84), Expect = 0.037 Identities = 23/66 (34%), Positives = 37/66 (56%), Gaps = 2/66 (3%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEWLA--EVNYLGQLSH 534 +GEG +G V+KG TG +VA+KK++L++ + A E++ L +L H Sbjct: 10 IGEGTYGVVYKGR---------HKATGQVVAMKKIRLENEEEGVPSTAIREISLLKELQH 60 Query: 535 PNLVKL 552 PN+V L Sbjct: 61 PNIVCL 66
>BUR1_KLULA (Q6CRA9) Serine/threonine-protein kinase BUR1 (EC 2.7.11.22) (EC| 2.7.11.23) Length = 645 Score = 37.0 bits (84), Expect = 0.037 Identities = 24/73 (32%), Positives = 39/73 (53%), Gaps = 2/73 (2%) Frame = +1 Query: 340 NFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEWLA--EVN 513 N+R + LG+G FG VFKG + GT VA+K++ + + + A E+ Sbjct: 54 NYREEEKLGQGTFGEVFKG---------IHLGTNRKVAIKRILVRAEKDLFPITAQREIT 104 Query: 514 YLGQLSHPNLVKL 552 L +++H N+VKL Sbjct: 105 ILKRMNHKNIVKL 117
>EPHA2_MOUSE (Q03145) Ephrin type-A receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) (MPK-5) (SEK-2) Length = 977 Score = 37.0 bits (84), Expect = 0.037 Identities = 26/84 (30%), Positives = 41/84 (48%), Gaps = 1/84 (1%) Frame = +1 Query: 304 KFTFSELKSCTRNFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQ 483 KFT SC ++G G FG V+KG + + P VA+K LK + Sbjct: 604 KFTTEIHPSCVAR---QKVIGAGEFGEVYKGTLKASSGKKEIP-----VAIKTLKAGYTE 655 Query: 484 GHK-EWLAEVNYLGQLSHPNLVKL 552 + ++L+E + +GQ SH N++ L Sbjct: 656 KQRVDFLSEASIMGQFSHHNIIPL 679
>CDC5_YEAST (P32562) Cell cycle serine/threonine-protein kinase CDC5/MSD2 (EC| 2.7.11.21) Length = 705 Score = 37.0 bits (84), Expect = 0.037 Identities = 27/89 (30%), Positives = 43/89 (48%), Gaps = 3/89 (3%) Frame = +1 Query: 292 SNLRKFTFSELKSCTRNFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVK---K 462 S L K S +K+ +++ LGEGGF F+ +K +G I A K K Sbjct: 65 SALCKTPPSLIKTRGKDYHRGHFLGEGGFARCFQ----------IKDDSGEIFAAKTVAK 114 Query: 463 LKLDSFQGHKEWLAEVNYLGQLSHPNLVK 549 + S + K+ L+E+ +SHPN+V+ Sbjct: 115 ASIKSEKTRKKLLSEIQIHKSMSHPNIVQ 143
>CDC2_PONPY (Q5RCH1) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 37.0 bits (84), Expect = 0.037 Identities = 25/66 (37%), Positives = 38/66 (57%), Gaps = 2/66 (3%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEWLA--EVNYLGQLSH 534 +GEG +G V+KG R T TG +V +KK++L+S + A E++ L +L H Sbjct: 10 IGEGTYGVVYKG----RHKT-----TGQVVTMKKIRLESEEEGVPSTAIREISLLKELRH 60 Query: 535 PNLVKL 552 PN+V L Sbjct: 61 PNIVSL 66
>STK10_MOUSE (O55098) Serine/threonine-protein kinase 10 (EC 2.7.11.1)| (Lymphocyte-oriented kinase) Length = 966 Score = 36.6 bits (83), Expect = 0.049 Identities = 26/99 (26%), Positives = 44/99 (44%), Gaps = 6/99 (6%) Frame = +1 Query: 274 KEILQSSNLRKFTFSELKSCTRNFRTDSL------LGEGGFGSVFKGWIDERTFTPVKPG 435 + IL+ S K E + R+ + + LG+G FG V+K E Sbjct: 7 RRILRLSTFEKRKSREYEHVRRDLDPNDVWEIVGELGDGAFGKVYKAKNKE--------- 57 Query: 436 TGMIVAVKKLKLDSFQGHKEWLAEVNYLGQLSHPNLVKL 552 TG + A K ++ S + ++++ E+ L HP +VKL Sbjct: 58 TGALAAAKVIETKSEEELEDYIVEIEILATCDHPYIVKL 96
>LCK_SAISC (Q95KR7) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) Length = 508 Score = 36.6 bits (83), Expect = 0.049 Identities = 26/64 (40%), Positives = 32/64 (50%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEWLAEVNYLGQLSHPN 540 LG G FG V+ G+ +E T VAVK LK S +LAE N + QL H Sbjct: 250 LGAGQFGEVWMGYYNEHTK----------VAVKSLKQGSMSPDA-FLAEANLMKQLQHKR 298 Query: 541 LVKL 552 LV+L Sbjct: 299 LVRL 302
>CDC2H_DICDI (P34117) CDC2-like serine/threonine-protein kinase CRP (EC| 2.7.11.22) (EC 2.7.11.23) Length = 292 Score = 36.6 bits (83), Expect = 0.049 Identities = 26/66 (39%), Positives = 36/66 (54%), Gaps = 2/66 (3%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEWLA--EVNYLGQLSH 534 LGEG +G V K E TG IVA+K+++LDS A E++ L +L H Sbjct: 10 LGEGTYGIVNKAKNRE---------TGEIVALKRIRLDSEDEGVPCTAIREISLLKELKH 60 Query: 535 PNLVKL 552 PN+V+L Sbjct: 61 PNIVRL 66
>CDK3_MOUSE (Q80YP0) Truncated cell division protein kinase 3 homolog| Length = 186 Score = 36.6 bits (83), Expect = 0.049 Identities = 24/72 (33%), Positives = 39/72 (54%), Gaps = 2/72 (2%) Frame = +1 Query: 343 FRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLD-SFQGHKEW-LAEVNY 516 F+ +GEG +G V+K TG +VA+KK++LD +G + E++ Sbjct: 4 FQKVEKIGEGTYGVVYKAR---------NKVTGQLVALKKIRLDLEAEGVPSTAVREISL 54 Query: 517 LGQLSHPNLVKL 552 L +L HPN++KL Sbjct: 55 LKELKHPNIIKL 66
>STK10_HUMAN (O94804) Serine/threonine-protein kinase 10 (EC 2.7.11.1)| (Lymphocyte-oriented kinase) Length = 968 Score = 36.6 bits (83), Expect = 0.049 Identities = 26/99 (26%), Positives = 44/99 (44%), Gaps = 6/99 (6%) Frame = +1 Query: 274 KEILQSSNLRKFTFSELKSCTRNFRTDSL------LGEGGFGSVFKGWIDERTFTPVKPG 435 + IL+ S K E + R+ + + LG+G FG V+K E Sbjct: 7 RRILRLSTFEKRKSREYEHVRRDLDPNEVWEIVGELGDGAFGKVYKAKNKE--------- 57 Query: 436 TGMIVAVKKLKLDSFQGHKEWLAEVNYLGQLSHPNLVKL 552 TG + A K ++ S + ++++ E+ L HP +VKL Sbjct: 58 TGALAAAKVIETKSEEELEDYIVEIEILATCDHPYIVKL 96
>RGS19_RAT (O70521) Regulator of G-protein signaling 19 (RGS19)| (G-alpha-interacting protein) (GAIP protein) Length = 216 Score = 36.2 bits (82), Expect = 0.063 Identities = 17/36 (47%), Positives = 20/36 (55%), Gaps = 3/36 (8%) Frame = -3 Query: 283 RSPSRSGESAAPT---TKNSCQKCWCQSHYCCCSWN 185 R PS S AAP+ ++N C CWC C CSWN Sbjct: 19 RPPSMSSHDAAPSGPPSRNPCCLCWCCC--CSCSWN 52
>RGS19_MOUSE (Q9CX84) Regulator of G-protein signaling 19 (RGS19)| Length = 216 Score = 36.2 bits (82), Expect = 0.063 Identities = 17/36 (47%), Positives = 20/36 (55%), Gaps = 3/36 (8%) Frame = -3 Query: 283 RSPSRSGESAAPT---TKNSCQKCWCQSHYCCCSWN 185 R PS S AAP+ ++N C CWC C CSWN Sbjct: 19 RPPSMSSHDAAPSGPPSRNPCCLCWCCC--CSCSWN 52
>CD2L5_HUMAN (Q14004) Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22)| (CDC2-related protein kinase 5) (Cholinesterase-related cell division controller) Length = 1512 Score = 36.2 bits (82), Expect = 0.063 Identities = 24/81 (29%), Positives = 41/81 (50%), Gaps = 5/81 (6%) Frame = +1 Query: 325 KSCTRNFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEW-- 498 K C F ++GEG +G V+K + TG +VA+KK++LD+ KE Sbjct: 699 KRCVDKFDIIGIIGEGTYGQVYKARDKD---------TGEMVALKKVRLDN---EKEGFP 746 Query: 499 ---LAEVNYLGQLSHPNLVKL 552 + E+ L QL+H +++ + Sbjct: 747 ITAIREIKILRQLTHQSIINM 767
>NTRK3_SAIBB (Q5IS82) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) Length = 825 Score = 36.2 bits (82), Expect = 0.063 Identities = 24/63 (38%), Positives = 32/63 (50%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEWLAEVNYLGQLSHPN 540 LGEG FG VF + +P K M+VAVK LK + K++ E L L H + Sbjct: 544 LGEGAFGKVFLA--ECYNLSPTKDK--MLVAVKALKDPTLAARKDFQREAELLTNLQHEH 599 Query: 541 LVK 549 +VK Sbjct: 600 IVK 602
>NTRK3_PANTR (Q5IS37) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) Length = 825 Score = 36.2 bits (82), Expect = 0.063 Identities = 24/63 (38%), Positives = 32/63 (50%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEWLAEVNYLGQLSHPN 540 LGEG FG VF + +P K M+VAVK LK + K++ E L L H + Sbjct: 544 LGEGAFGKVFLA--ECYNLSPTKDK--MLVAVKALKDPTLAARKDFQREAELLTNLQHEH 599 Query: 541 LVK 549 +VK Sbjct: 600 IVK 602
>NTRK3_MACFA (Q5IFJ9) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) Length = 825 Score = 36.2 bits (82), Expect = 0.063 Identities = 24/63 (38%), Positives = 32/63 (50%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEWLAEVNYLGQLSHPN 540 LGEG FG VF + +P K M+VAVK LK + K++ E L L H + Sbjct: 544 LGEGAFGKVFLA--ECYNLSPTKDK--MLVAVKALKDPTLAARKDFQREAELLTNLQHEH 599 Query: 541 LVK 549 +VK Sbjct: 600 IVK 602
>PHO85_DEBHA (Q6BRY2) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 330 Score = 36.2 bits (82), Expect = 0.063 Identities = 23/65 (35%), Positives = 37/65 (56%), Gaps = 1/65 (1%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEW-LAEVNYLGQLSHP 537 LGEG + +V+KG RT G +VA+K++ LDS +G + E++ + +L H Sbjct: 14 LGEGTYATVYKG--RNRT-------NGQLVALKEINLDSEEGTPSTAIREISLMKELDHE 64 Query: 538 NLVKL 552 N+V L Sbjct: 65 NIVTL 69
>KPEL_DROME (Q05652) Probable serine/threonine-protein kinase pelle (EC| 2.7.11.1) Length = 501 Score = 36.2 bits (82), Expect = 0.063 Identities = 23/89 (25%), Positives = 44/89 (49%), Gaps = 1/89 (1%) Frame = +1 Query: 289 SSNLRKFTFSELKSCTRNFRTDSLLGEGGFGSVFKG-WIDERTFTPVKPGTGMIVAVKKL 465 + +L + ++EL++ T + D+ LG+GGFG V++G W V + K + Sbjct: 195 AESLLEIDYAELENATDGWSPDNRLGQGGFGDVYRGKWKQLDVAIKVMNYRSPNIDQKMV 254 Query: 466 KLDSFQGHKEWLAEVNYLGQLSHPNLVKL 552 +L ++ E+ YL + H N++ L Sbjct: 255 EL------QQSYNELKYLNSIRHDNILAL 277
>TIE1_HUMAN (P35590) Tyrosine-protein kinase receptor Tie-1 precursor (EC| 2.7.10.1) Length = 1138 Score = 36.2 bits (82), Expect = 0.063 Identities = 24/69 (34%), Positives = 35/69 (50%), Gaps = 2/69 (2%) Frame = +1 Query: 352 DSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLK-LDSFQGHKEWLAEVNYLGQL 528 + L+GEG FG V + I K G M A+K LK S H+++ E+ L +L Sbjct: 842 EDLIGEGNFGQVIRAMIK-------KDGLKMNAAIKMLKEYASENDHRDFAGELEVLCKL 894 Query: 529 S-HPNLVKL 552 HPN++ L Sbjct: 895 GHHPNIINL 903
>TIE1_BOVIN (Q06805) Tyrosine-protein kinase receptor Tie-1 precursor (EC| 2.7.10.1) Length = 1136 Score = 36.2 bits (82), Expect = 0.063 Identities = 24/69 (34%), Positives = 35/69 (50%), Gaps = 2/69 (2%) Frame = +1 Query: 352 DSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLK-LDSFQGHKEWLAEVNYLGQL 528 + L+GEG FG V + I K G M A+K LK S H+++ E+ L +L Sbjct: 840 EDLIGEGNFGQVIRAMIK-------KDGLKMNAAIKMLKEYASENDHRDFAGELEVLCKL 892 Query: 529 S-HPNLVKL 552 HPN++ L Sbjct: 893 GHHPNIINL 901
>CD2L5_MOUSE (Q69ZA1) Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22)| (CDC2-related protein kinase 5) Length = 1511 Score = 36.2 bits (82), Expect = 0.063 Identities = 24/81 (29%), Positives = 41/81 (50%), Gaps = 5/81 (6%) Frame = +1 Query: 325 KSCTRNFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEW-- 498 K C F ++GEG +G V+K + TG +VA+KK++LD+ KE Sbjct: 699 KRCVDKFDIIGIIGEGTYGQVYKARDKD---------TGEMVALKKVRLDN---EKEGFP 746 Query: 499 ---LAEVNYLGQLSHPNLVKL 552 + E+ L QL+H +++ + Sbjct: 747 ITAIREIKILRQLTHQSIINM 767
>NTRK3_RAT (Q03351) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (GP145-TrkC) (Trk-C) Length = 864 Score = 36.2 bits (82), Expect = 0.063 Identities = 24/63 (38%), Positives = 32/63 (50%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEWLAEVNYLGQLSHPN 540 LGEG FG VF + +P K M+VAVK LK + K++ E L L H + Sbjct: 544 LGEGAFGKVFLA--ECYNLSPTKDK--MLVAVKALKDPTLAARKDFQREAELLTNLQHEH 599 Query: 541 LVK 549 +VK Sbjct: 600 IVK 602
>NTRK3_HUMAN (Q16288) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (GP145-TrkC) (Trk-C) Length = 839 Score = 36.2 bits (82), Expect = 0.063 Identities = 24/63 (38%), Positives = 32/63 (50%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEWLAEVNYLGQLSHPN 540 LGEG FG VF + +P K M+VAVK LK + K++ E L L H + Sbjct: 544 LGEGAFGKVFLA--ECYNLSPTKDK--MLVAVKALKDPTLAARKDFQREAELLTNLQHEH 599 Query: 541 LVK 549 +VK Sbjct: 600 IVK 602
>CDKL1_BRARE (Q6AXJ9) Cyclin-dependent kinase-like 1 (EC 2.7.11.22)| Length = 350 Score = 36.2 bits (82), Expect = 0.063 Identities = 28/68 (41%), Positives = 33/68 (48%), Gaps = 2/68 (2%) Frame = +1 Query: 355 SLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKL--KLDSFQGHKEWLAEVNYLGQL 528 S +GEG +G VFK + TG IVA+KK D K L E+ L QL Sbjct: 8 SKIGEGSYGVVFKCRNKD---------TGQIVAIKKFVESEDDPIIKKIALREIRMLKQL 58 Query: 529 SHPNLVKL 552 HPNLV L Sbjct: 59 KHPNLVNL 66
>BUR1_YEAST (P23293) Serine/threonine-protein kinase BUR1 (EC 2.7.11.22) (EC| 2.7.11.23) (Suppressor of GPA1-Vall50 mutation protein 1) (Bypass UAS requirement protein 1) Length = 657 Score = 36.2 bits (82), Expect = 0.063 Identities = 29/89 (32%), Positives = 49/89 (55%), Gaps = 4/89 (4%) Frame = +1 Query: 298 LRKFTFSELKSCT---RNFRTDSLLGEGGFGSVFKG-WIDERTFTPVKPGTGMIVAVKKL 465 LRK + ++ CT ++R D LG+G FG V+KG ++ + +K +IV+V+K Sbjct: 42 LRKRSSEKVYGCTVFQNHYREDEKLGQGTFGEVYKGIHLETQRQVAMKK---IIVSVEK- 97 Query: 466 KLDSFQGHKEWLAEVNYLGQLSHPNLVKL 552 D F + E+ L +L+H N++KL Sbjct: 98 --DLFPITAQ--REITILKRLNHKNIIKL 122
>TIE1_MOUSE (Q06806) Tyrosine-protein kinase receptor Tie-1 precursor (EC| 2.7.10.1) Length = 1134 Score = 36.2 bits (82), Expect = 0.063 Identities = 24/69 (34%), Positives = 35/69 (50%), Gaps = 2/69 (2%) Frame = +1 Query: 352 DSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLK-LDSFQGHKEWLAEVNYLGQL 528 + L+GEG FG V + I K G M A+K LK S H+++ E+ L +L Sbjct: 838 EDLIGEGNFGQVIRAMIK-------KDGLKMNAAIKMLKEYASENDHRDFAGELEVLCKL 890 Query: 529 S-HPNLVKL 552 HPN++ L Sbjct: 891 GHHPNIINL 899
>EPHA6_RAT (P54758) Ephrin type-A receptor 6 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2) Length = 1035 Score = 36.2 bits (82), Expect = 0.063 Identities = 24/70 (34%), Positives = 38/70 (54%), Gaps = 1/70 (1%) Frame = +1 Query: 346 RTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSF-QGHKEWLAEVNYLG 522 R + ++G G FG V G R TP K + VA+K LK + +++L E + +G Sbjct: 631 RIERVIGAGEFGEVCSG----RLKTPGK--REIPVAIKTLKGGHMDRQRRDFLREASIMG 684 Query: 523 QLSHPNLVKL 552 Q HPN+++L Sbjct: 685 QFDHPNIIRL 694
>EPHA6_MOUSE (Q62413) Ephrin type-A receptor 6 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2) Length = 1035 Score = 36.2 bits (82), Expect = 0.063 Identities = 24/70 (34%), Positives = 38/70 (54%), Gaps = 1/70 (1%) Frame = +1 Query: 346 RTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSF-QGHKEWLAEVNYLG 522 R + ++G G FG V G R TP K + VA+K LK + +++L E + +G Sbjct: 631 RIERVIGAGEFGEVCSG----RLKTPGK--REIPVAIKTLKGGHMDRQRRDFLREASIMG 684 Query: 523 QLSHPNLVKL 552 Q HPN+++L Sbjct: 685 QFDHPNIIRL 694
>EPHA6_HUMAN (Q9UF33) Ephrin type-A receptor 6 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2) Length = 1035 Score = 36.2 bits (82), Expect = 0.063 Identities = 24/70 (34%), Positives = 38/70 (54%), Gaps = 1/70 (1%) Frame = +1 Query: 346 RTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSF-QGHKEWLAEVNYLG 522 R + ++G G FG V G R TP K + VA+K LK + +++L E + +G Sbjct: 631 RIERVIGAGEFGEVCSG----RLKTPGK--REIPVAIKTLKGGHMDRQRRDFLREASIMG 684 Query: 523 QLSHPNLVKL 552 Q HPN+++L Sbjct: 685 QFDHPNIIRL 694
>EPHA1_MOUSE (Q60750) Ephrin type-A receptor 1 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ESK) Length = 977 Score = 36.2 bits (82), Expect = 0.063 Identities = 22/68 (32%), Positives = 38/68 (55%), Gaps = 1/68 (1%) Frame = +1 Query: 352 DSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGH-KEWLAEVNYLGQL 528 D+++GEG FG V++G + + VA+K LK S G+ +L E +GQ Sbjct: 628 DTVIGEGEFGEVYRGAL------RLPSQDCKTVAIKTLKDTSPDGYWWNFLREATIMGQF 681 Query: 529 SHPNLVKL 552 +HP++++L Sbjct: 682 NHPHILRL 689
>IKKB_HUMAN (O14920) Inhibitor of nuclear factor kappa B kinase beta subunit| (EC 2.7.11.10) (I-kappa-B-kinase beta) (IkBKB) (IKK-beta) (IKK-B) (I-kappa-B kinase 2) (IKK2) (Nuclear factor NF-kappa-B inhibitor kinase beta) (NFKBIKB) Length = 756 Score = 35.8 bits (81), Expect = 0.083 Identities = 20/63 (31%), Positives = 36/63 (57%), Gaps = 1/63 (1%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLD-SFQGHKEWLAEVNYLGQLSHP 537 LG GGFG+V + W ++ T G +A+K+ + + S + + W E+ + +L+HP Sbjct: 21 LGTGGFGNVIR-WHNQET--------GEQIAIKQCRQELSPRNRERWCLEIQIMRRLTHP 71 Query: 538 NLV 546 N+V Sbjct: 72 NVV 74
>EPHA4_MOUSE (Q03137) Ephrin type-A receptor 4 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor SEK) (MPK-3) Length = 986 Score = 35.8 bits (81), Expect = 0.083 Identities = 26/92 (28%), Positives = 44/92 (47%), Gaps = 10/92 (10%) Frame = +1 Query: 307 FTFSELKSCTRNF---------RTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVK 459 FT+ + R F + + ++G G FG V G R P K + VA+K Sbjct: 600 FTYEDPNQAVREFAKEIDASCIKIEKVIGVGEFGEVCSG----RLKVPGK--REICVAIK 653 Query: 460 KLKLD-SFQGHKEWLAEVNYLGQLSHPNLVKL 552 LK + + +++L+E + +GQ HPN++ L Sbjct: 654 TLKAGYTDKQRRDFLSEASIMGQFDHPNIIHL 685
>EPHA4_HUMAN (P54764) Ephrin type-A receptor 4 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor SEK) (Receptor protein-tyrosine kinase HEK8) Length = 986 Score = 35.8 bits (81), Expect = 0.083 Identities = 26/92 (28%), Positives = 44/92 (47%), Gaps = 10/92 (10%) Frame = +1 Query: 307 FTFSELKSCTRNF---------RTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVK 459 FT+ + R F + + ++G G FG V G R P K + VA+K Sbjct: 600 FTYEDPNQAVREFAKEIDASCIKIEKVIGVGEFGEVCSG----RLKVPGK--REICVAIK 653 Query: 460 KLKLD-SFQGHKEWLAEVNYLGQLSHPNLVKL 552 LK + + +++L+E + +GQ HPN++ L Sbjct: 654 TLKAGYTDKQRRDFLSEASIMGQFDHPNIIHL 685
>EPHA4_CHICK (Q07496) Ephrin type-A receptor 4 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor CEK8) Length = 986 Score = 35.8 bits (81), Expect = 0.083 Identities = 26/92 (28%), Positives = 44/92 (47%), Gaps = 10/92 (10%) Frame = +1 Query: 307 FTFSELKSCTRNF---------RTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVK 459 FT+ + R F + + ++G G FG V G R P K + VA+K Sbjct: 600 FTYEDPNQAVREFAKEIDASCIKIEKVIGVGEFGEVCSG----RLKVPGK--REICVAIK 653 Query: 460 KLKLD-SFQGHKEWLAEVNYLGQLSHPNLVKL 552 LK + + +++L+E + +GQ HPN++ L Sbjct: 654 TLKAGYTDKQRRDFLSEASIMGQFDHPNIIHL 685
>EPA4A_XENLA (Q91845) Ephrin type-A receptor 4-A precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor SEK-1) (xSEK-1) Length = 986 Score = 35.8 bits (81), Expect = 0.083 Identities = 26/92 (28%), Positives = 44/92 (47%), Gaps = 10/92 (10%) Frame = +1 Query: 307 FTFSELKSCTRNF---------RTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVK 459 FT+ + R F + + ++G G FG V G R P K + VA+K Sbjct: 599 FTYEDPNQAVREFAKEIDASCIKIEKVIGVGEFGEVCSG----RLKVPGK--REIYVAIK 652 Query: 460 KLKLD-SFQGHKEWLAEVNYLGQLSHPNLVKL 552 LK + + +++L+E + +GQ HPN++ L Sbjct: 653 TLKAGYTDKQRRDFLSEASIMGQFDHPNIIHL 684
>RET_HUMAN (P07949) Proto-oncogene tyrosine-protein kinase receptor ret| precursor (EC 2.7.10.1) (C-ret) Length = 1114 Score = 35.8 bits (81), Expect = 0.083 Identities = 27/74 (36%), Positives = 39/74 (52%), Gaps = 2/74 (2%) Frame = +1 Query: 337 RNFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMI-VAVKKLKLDSFQGH-KEWLAEV 510 +N LGEG FG V K T +K G VAVK LK ++ ++ L+E Sbjct: 722 KNLVLGKTLGEGEFGKVVKA-----TAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEF 776 Query: 511 NYLGQLSHPNLVKL 552 N L Q++HP+++KL Sbjct: 777 NVLKQVNHPHVIKL 790
>EPA4B_XENLA (Q91694) Ephrin type-A receptor 4-B precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor PAG) (Pagliaccio) Length = 985 Score = 35.8 bits (81), Expect = 0.083 Identities = 26/92 (28%), Positives = 44/92 (47%), Gaps = 10/92 (10%) Frame = +1 Query: 307 FTFSELKSCTRNF---------RTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVK 459 FT+ + R F + + ++G G FG V G R P K + VA+K Sbjct: 599 FTYEDPNQAVREFAKEIDASCIKIEKVIGVGEFGEVCSG----RLKVPGK--REIYVAIK 652 Query: 460 KLKLD-SFQGHKEWLAEVNYLGQLSHPNLVKL 552 LK + + +++L+E + +GQ HPN++ L Sbjct: 653 TLKAGYTDKQRRDFLSEASIMGQFDHPNIIHL 684
>CDC2C_DROME (P23573) Cell division control protein 2 cognate (EC 2.7.11.22) (EC| 2.7.11.23) Length = 314 Score = 35.8 bits (81), Expect = 0.083 Identities = 25/76 (32%), Positives = 39/76 (51%), Gaps = 5/76 (6%) Frame = +1 Query: 340 NFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEW-----LA 504 NF+ +GEG +G V+K + TG VA+KK++L+ G E + Sbjct: 7 NFQRAEKIGEGTYGIVYKARSNS---------TGQDVALKKIRLE---GETEGVPSTAIR 54 Query: 505 EVNYLGQLSHPNLVKL 552 E++ L L HPN+V+L Sbjct: 55 EISLLKNLKHPNVVQL 70
>EPHB2_MOUSE (P54763) Ephrin type-B receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH-3) (Neural kinase) (Nuk receptor tyrosine kinase) (SEK-3) Length = 994 Score = 35.4 bits (80), Expect = 0.11 Identities = 26/93 (27%), Positives = 44/93 (47%), Gaps = 11/93 (11%) Frame = +1 Query: 307 FTFSELKSCTRNF---------RTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMI-VAV 456 FT+ + R F + + ++G G FG V G + PG I VA+ Sbjct: 608 FTYEDPNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLK-------LPGKREIFVAI 660 Query: 457 KKLKLD-SFQGHKEWLAEVNYLGQLSHPNLVKL 552 K LK + + +++L+E + +GQ HPN++ L Sbjct: 661 KTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHL 693
>STK4_HUMAN (Q13043) Serine/threonine-protein kinase 4 (EC 2.7.11.1)| (STE20-like kinase MST1) (MST-1) (Mammalian STE20-like protein kinase 1) (Serine/threonine-protein kinase Krs-2) Length = 487 Score = 35.4 bits (80), Expect = 0.11 Identities = 21/63 (33%), Positives = 36/63 (57%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEWLAEVNYLGQLSHPN 540 LGEG +GSV+K + TG IVA+K++ ++S +E + E++ + Q P+ Sbjct: 36 LGEGSYGSVYKA---------IHKETGQIVAIKQVPVES--DLQEIIKEISIMQQCDSPH 84 Query: 541 LVK 549 +VK Sbjct: 85 VVK 87
>EPHB2_HUMAN (P29323) Ephrin type-B receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH-3) (DRT) (Receptor protein-tyrosine kinase HEK5) (ERK) (NY-REN-47 antigen) Length = 1055 Score = 35.4 bits (80), Expect = 0.11 Identities = 26/93 (27%), Positives = 44/93 (47%), Gaps = 11/93 (11%) Frame = +1 Query: 307 FTFSELKSCTRNF---------RTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMI-VAV 456 FT+ + R F + + ++G G FG V G + PG I VA+ Sbjct: 600 FTYEDPNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLK-------LPGKREIFVAI 652 Query: 457 KKLKLD-SFQGHKEWLAEVNYLGQLSHPNLVKL 552 K LK + + +++L+E + +GQ HPN++ L Sbjct: 653 KTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHL 685
>LCK_AOTNA (Q5PXS1) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) Length = 508 Score = 35.4 bits (80), Expect = 0.11 Identities = 25/64 (39%), Positives = 32/64 (50%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEWLAEVNYLGQLSHPN 540 LG G FG V+ G+ ++ T VAVK LK S +LAE N + QL H Sbjct: 250 LGAGQFGEVWMGYYNDHTK----------VAVKSLKQGSMSPDA-FLAEANLMKQLQHQR 298 Query: 541 LVKL 552 LV+L Sbjct: 299 LVRL 302
>CDKL4_MOUSE (Q3TZA2) Cyclin-dependent kinase-like 4 (EC 2.7.11.22)| Length = 342 Score = 35.4 bits (80), Expect = 0.11 Identities = 25/66 (37%), Positives = 31/66 (46%), Gaps = 2/66 (3%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKL--KLDSFQGHKEWLAEVNYLGQLSH 534 +GEG +G VFK +G +VA+KK D K L E+ L QL H Sbjct: 10 IGEGSYGVVFKCR---------NKSSGQVVAIKKFVESEDDRVVRKIALREIRMLKQLKH 60 Query: 535 PNLVKL 552 PNLV L Sbjct: 61 PNLVNL 66
>KIN31_CAEEL (P34265) Probable tyrosine-protein kinase kin-31 (EC 2.7.10.2)| Length = 437 Score = 35.4 bits (80), Expect = 0.11 Identities = 24/72 (33%), Positives = 36/72 (50%), Gaps = 2/72 (2%) Frame = +1 Query: 340 NFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGH--KEWLAEVN 513 N + LGEG FG V G + + + G + VAVK++K D K++L E Sbjct: 129 NIVIEKKLGEGAFGEVSSGVMKFK-----RGGRLVKVAVKQVKTDGIGKDQIKDFLMEAR 183 Query: 514 YLGQLSHPNLVK 549 + L HPN+V+ Sbjct: 184 TMRNLGHPNIVR 195
>ABL1_CAEEL (P03949) Tyrosine-protein kinase abl-1 (EC 2.7.10.2)| Length = 1224 Score = 35.4 bits (80), Expect = 0.11 Identities = 24/64 (37%), Positives = 33/64 (51%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEWLAEVNYLGQLSHPN 540 LG G +G V++G+ T +AVK LK D+ H E+LAE + L H N Sbjct: 317 LGGGQYGDVYEGYWKRHDCT---------IAVKALKEDAMPLH-EFLAEAAIMKDLHHKN 366 Query: 541 LVKL 552 LV+L Sbjct: 367 LVRL 370
>TIE2_MOUSE (Q02858) Angiopoietin-1 receptor precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen) Length = 1122 Score = 35.4 bits (80), Expect = 0.11 Identities = 23/73 (31%), Positives = 37/73 (50%), Gaps = 2/73 (2%) Frame = +1 Query: 340 NFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLK-LDSFQGHKEWLAEVNY 516 + + ++GEG FG V K I K G M A+K++K S H+++ E+ Sbjct: 821 DIKFQDVIGEGNFGQVLKARIK-------KDGLRMDAAIKRMKEYASKDDHRDFAGELEV 873 Query: 517 LGQLS-HPNLVKL 552 L +L HPN++ L Sbjct: 874 LCKLGHHPNIINL 886
>EPHB2_COTJA (Q90344) Ephrin type-B receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor QEK5) Length = 987 Score = 35.4 bits (80), Expect = 0.11 Identities = 26/93 (27%), Positives = 44/93 (47%), Gaps = 11/93 (11%) Frame = +1 Query: 307 FTFSELKSCTRNF---------RTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMI-VAV 456 FT+ + R F + + ++G G FG V G + PG I VA+ Sbjct: 601 FTYEDPNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLK-------LPGKREIFVAI 653 Query: 457 KKLKLD-SFQGHKEWLAEVNYLGQLSHPNLVKL 552 K LK + + +++L+E + +GQ HPN++ L Sbjct: 654 KTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHL 686
>TIE2_HUMAN (Q02763) Angiopoietin-1 receptor precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen) Length = 1124 Score = 35.4 bits (80), Expect = 0.11 Identities = 23/73 (31%), Positives = 37/73 (50%), Gaps = 2/73 (2%) Frame = +1 Query: 340 NFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLK-LDSFQGHKEWLAEVNY 516 + + ++GEG FG V K I K G M A+K++K S H+++ E+ Sbjct: 823 DIKFQDVIGEGNFGQVLKARIK-------KDGLRMDAAIKRMKEYASKDDHRDFAGELEV 875 Query: 517 LGQLS-HPNLVKL 552 L +L HPN++ L Sbjct: 876 LCKLGHHPNIINL 888
>IKKB_MOUSE (O88351) Inhibitor of nuclear factor kappa B kinase beta subunit| (EC 2.7.11.10) (I-kappa-B-kinase beta) (IkBKB) (IKK-beta) (IKK-B) (I-kappa-B kinase 2) (IKK2) (Nuclear factor NF-kappa-B inhibitor kinase beta) (NFKBIKB) Length = 757 Score = 35.4 bits (80), Expect = 0.11 Identities = 20/63 (31%), Positives = 35/63 (55%), Gaps = 1/63 (1%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLD-SFQGHKEWLAEVNYLGQLSHP 537 LG GGFG+V + W ++ TG +A+K+ + + S + W E+ + +L+HP Sbjct: 21 LGTGGFGNVIR-WHNQ--------ATGEQIAIKQCRQELSPKNRNRWCLEIQIMRRLNHP 71 Query: 538 NLV 546 N+V Sbjct: 72 NVV 74
>CDKL1_HUMAN (Q00532) Cyclin-dependent kinase-like 1 (EC 2.7.11.22)| (Serine/threonine-protein kinase KKIALRE) (Protein kinase p42 KKIALRE) Length = 357 Score = 35.4 bits (80), Expect = 0.11 Identities = 28/67 (41%), Positives = 34/67 (50%), Gaps = 3/67 (4%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQG---HKEWLAEVNYLGQLS 531 +GEG +G VFK + TG IVA+KK L+S K L E+ L QL Sbjct: 10 IGEGSYGVVFKCRNRD---------TGQIVAIKKF-LESEDDPVIKKIALREIRMLKQLK 59 Query: 532 HPNLVKL 552 HPNLV L Sbjct: 60 HPNLVNL 66
>NTRK3_CHICK (Q91044) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (Trk-C) Length = 827 Score = 35.4 bits (80), Expect = 0.11 Identities = 24/63 (38%), Positives = 31/63 (49%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEWLAEVNYLGQLSHPN 540 LGEG FG VF + T K M+VAVK LK + K++ E L L H + Sbjct: 546 LGEGAFGKVFLAECYNLSPTNDK----MLVAVKALKDPTLAARKDFQREAELLTNLQHEH 601 Query: 541 LVK 549 +VK Sbjct: 602 IVK 604
>EPHB2_CHICK (P28693) Ephrin type-B receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor CEK5) Length = 1004 Score = 35.4 bits (80), Expect = 0.11 Identities = 26/93 (27%), Positives = 44/93 (47%), Gaps = 11/93 (11%) Frame = +1 Query: 307 FTFSELKSCTRNF---------RTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMI-VAV 456 FT+ + R F + + ++G G FG V G + PG I VA+ Sbjct: 618 FTYEDPNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLK-------LPGKREIFVAI 670 Query: 457 KKLKLD-SFQGHKEWLAEVNYLGQLSHPNLVKL 552 K LK + + +++L+E + +GQ HPN++ L Sbjct: 671 KTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHL 703
>TIE2_BOVIN (Q06807) Angiopoietin-1 receptor precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor TIE-2) (CD202b antigen) Length = 1125 Score = 35.4 bits (80), Expect = 0.11 Identities = 23/73 (31%), Positives = 37/73 (50%), Gaps = 2/73 (2%) Frame = +1 Query: 340 NFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLK-LDSFQGHKEWLAEVNY 516 + + ++GEG FG V K I K G M A+K++K S H+++ E+ Sbjct: 824 DIKFQDVIGEGNFGQVLKARIK-------KDGLRMDAAIKRMKEYASKDDHRDFAGELEV 876 Query: 517 LGQLS-HPNLVKL 552 L +L HPN++ L Sbjct: 877 LCKLGHHPNIINL 889
>ROS_AVISU (P00529) Tyrosine-protein kinase transforming protein ros (EC| 2.7.10.1) Length = 402 Score = 35.0 bits (79), Expect = 0.14 Identities = 24/67 (35%), Positives = 36/67 (53%), Gaps = 2/67 (2%) Frame = +1 Query: 358 LLGEGGFGSVFKGWIDERTFTPVKPGTG-MIVAVKKLKLDSFQGHK-EWLAEVNYLGQLS 531 LLG G FG V++G + G+G VAVK LK + K E+L E + + + Sbjct: 103 LLGSGAFGEVYEG----TALDILADGSGESRVAVKTLKRGATDQEKSEFLKEAHLMSKFD 158 Query: 532 HPNLVKL 552 HP+++KL Sbjct: 159 HPHILKL 165
>CD2L7_HUMAN (Q9NYV4) Cell division cycle 2-related protein kinase 7 (EC| 2.7.11.22) (CDC2-related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS) Length = 1490 Score = 35.0 bits (79), Expect = 0.14 Identities = 25/81 (30%), Positives = 40/81 (49%), Gaps = 5/81 (6%) Frame = +1 Query: 325 KSCTRNFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEW-- 498 K C F ++GEG +G V+K + TG +VA+KK++LD+ KE Sbjct: 721 KRCVDKFDIIGIIGEGTYGQVYKARDKD---------TGELVALKKVRLDN---EKEGFP 768 Query: 499 ---LAEVNYLGQLSHPNLVKL 552 + E+ L QL H ++V + Sbjct: 769 ITAIREIKILRQLIHRSVVNM 789
>TAO1B_XENLA (Q7ZYJ0) Serine/threonine-protein kinase TAO1-B (EC 2.7.11.1)| (Thousand and one amino acid protein 1-B) Length = 1001 Score = 35.0 bits (79), Expect = 0.14 Identities = 20/66 (30%), Positives = 35/66 (53%), Gaps = 3/66 (4%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEW---LAEVNYLGQLS 531 +G G FG+V+ D RT +VA+KK+ Q +++W + EV +L ++ Sbjct: 34 IGHGSFGAVYFAH-DART--------SEVVAIKKMSYSGKQSNEKWQDIIKEVKFLQRIQ 84 Query: 532 HPNLVK 549 HPN ++ Sbjct: 85 HPNSIE 90
>ABL_MLVAB (P00521) Tyrosine-protein kinase transforming protein Abl (EC| 2.7.10.2) (V-abl) Length = 746 Score = 35.0 bits (79), Expect = 0.14 Identities = 23/64 (35%), Positives = 36/64 (56%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEWLAEVNYLGQLSHPN 540 LG G +G V++G + + T VAVK LK D+ + +E+L E + ++ HPN Sbjct: 134 LGGGQYGEVYEGVWKKYSLT---------VAVKTLKEDTMEV-EEFLKEAAVMKEIKHPN 183 Query: 541 LVKL 552 LV+L Sbjct: 184 LVQL 187
>ROR2_DROME (Q9V6K3) Tyrosine-protein kinase transmembrane receptor Ror2| precursor (EC 2.7.10.1) (Neurospecific receptor tyrosine kinase) Length = 724 Score = 35.0 bits (79), Expect = 0.14 Identities = 25/65 (38%), Positives = 34/65 (52%), Gaps = 1/65 (1%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLD-SFQGHKEWLAEVNYLGQLSHP 537 LG+G FG VF+ R V ++VAVK LK D S Q ++ E L + HP Sbjct: 447 LGQGAFGRVFQA----RAPGLVPDQEDLLVAVKMLKDDASDQMQMDFEREACLLAEFDHP 502 Query: 538 NLVKL 552 N+V+L Sbjct: 503 NIVRL 507
>JAK_DROME (Q24592) Tyrosine-protein kinase hopscotch (EC 2.7.10.2)| Length = 1177 Score = 35.0 bits (79), Expect = 0.14 Identities = 21/73 (28%), Positives = 39/73 (53%) Frame = +1 Query: 331 CTRNFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEWLAEV 510 C + ++++G G +G+V+KG ++ K VA+K L ++ Q ++ E+ Sbjct: 888 CRVIYNMENMIGRGHYGTVYKGHLEFND----KDQPREQVAIKML--NTMQVSTDFHREI 941 Query: 511 NYLGQLSHPNLVK 549 + LSHPN+VK Sbjct: 942 GIMRTLSHPNIVK 954
>ABL1_HUMAN (P00519) Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2)| (p150) (c-ABL) (Abelson murine leukemia viral oncogene homolog 1) Length = 1130 Score = 35.0 bits (79), Expect = 0.14 Identities = 23/64 (35%), Positives = 36/64 (56%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEWLAEVNYLGQLSHPN 540 LG G +G V++G + + T VAVK LK D+ + +E+L E + ++ HPN Sbjct: 248 LGGGQYGEVYEGVWKKYSLT---------VAVKTLKEDTMEV-EEFLKEAAVMKEIKHPN 297 Query: 541 LVKL 552 LV+L Sbjct: 298 LVQL 301
>ROS_CHICK (P08941) Proto-oncogene tyrosine-protein kinase ROS precursor (EC| 2.7.10.1) (c-ros-1) Length = 2311 Score = 35.0 bits (79), Expect = 0.14 Identities = 24/67 (35%), Positives = 36/67 (53%), Gaps = 2/67 (2%) Frame = +1 Query: 358 LLGEGGFGSVFKGWIDERTFTPVKPGTG-MIVAVKKLKLDSFQGHK-EWLAEVNYLGQLS 531 LLG G FG V++G + G+G VAVK LK + K E+L E + + + Sbjct: 1966 LLGSGAFGEVYEG----TALDILADGSGESRVAVKTLKRGATDQEKSEFLKEAHLMSKFD 2021 Query: 532 HPNLVKL 552 HP+++KL Sbjct: 2022 HPHILKL 2028
>ABL_FSVHY (P10447) Tyrosine-protein kinase transforming protein Abl (EC| 2.7.10.2) (V-abl) Length = 439 Score = 35.0 bits (79), Expect = 0.14 Identities = 23/64 (35%), Positives = 36/64 (56%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEWLAEVNYLGQLSHPN 540 LG G +G V++G + + T VAVK LK D+ + +E+L E + ++ HPN Sbjct: 197 LGGGQYGEVYEGVWKKYSLT---------VAVKTLKEDTMEV-EEFLKEAAVMKEIKHPN 246 Query: 541 LVKL 552 LV+L Sbjct: 247 LVQL 250
>RPK1_IPONI (P93194) Receptor-like protein kinase precursor (EC 2.7.11.1)| Length = 1109 Score = 35.0 bits (79), Expect = 0.14 Identities = 22/80 (27%), Positives = 40/80 (50%), Gaps = 1/80 (1%) Frame = +1 Query: 316 SELKSCTRNFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQ-GHK 492 +++ T N ++G+G G+++K T +P K + AVKKL + G Sbjct: 807 NKVLEATENLNDKYVIGKGAHGTIYKA-----TLSPDK-----VYAVKKLVFTGIKNGSV 856 Query: 493 EWLAEVNYLGQLSHPNLVKL 552 + E+ +G++ H NL+KL Sbjct: 857 SMVREIETIGKVRHRNLIKL 876
>ROR1_DROME (Q24488) Tyrosine-protein kinase transmembrane receptor Ror| precursor (EC 2.7.10.1) (dRor) Length = 685 Score = 35.0 bits (79), Expect = 0.14 Identities = 23/63 (36%), Positives = 35/63 (55%), Gaps = 1/63 (1%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLD-SFQGHKEWLAEVNYLGQLSHP 537 LGEG FG V+KG + P K T + VA+K LK + S + +++ E+ + L H Sbjct: 416 LGEGAFGKVYKG----QLLQPNK--TTITVAIKALKENASVKTQQDFKREIELISDLKHQ 469 Query: 538 NLV 546 N+V Sbjct: 470 NIV 472
>ABL1_MOUSE (P00520) Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2)| (p150) (c-ABL) (Abelson murine leukemia viral oncogene homolog 1) Length = 1123 Score = 35.0 bits (79), Expect = 0.14 Identities = 23/64 (35%), Positives = 36/64 (56%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEWLAEVNYLGQLSHPN 540 LG G +G V++G + + T VAVK LK D+ + +E+L E + ++ HPN Sbjct: 248 LGGGQYGEVYEGVWKKYSLT---------VAVKTLKEDTMEV-EEFLKEAAVMKEIKHPN 297 Query: 541 LVKL 552 LV+L Sbjct: 298 LVQL 301
>LCK_CHICK (P42683) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (Protein-tyrosine kinase C-TKL) (p56tk1) Length = 507 Score = 34.7 bits (78), Expect = 0.18 Identities = 24/64 (37%), Positives = 31/64 (48%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEWLAEVNYLGQLSHPN 540 LG G FG V+ G+ + T VA+K LK S +LAE N + L HP Sbjct: 249 LGAGQFGEVWMGFYNGHTK----------VAIKNLKQGSMSP-SAFLAEANLMKNLQHPR 297 Query: 541 LVKL 552 LV+L Sbjct: 298 LVRL 301
>CDC7_SCHPO (P41892) Cell division control protein 7 (EC 2.7.11.1)| Length = 1062 Score = 34.7 bits (78), Expect = 0.18 Identities = 25/67 (37%), Positives = 35/67 (52%), Gaps = 4/67 (5%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEWLA----EVNYLGQL 528 LG+G FG+V++G + G VAVKK+KL K L+ E++ L L Sbjct: 15 LGKGAFGAVYRG---------LNIKNGETVAVKKVKLSKML--KSDLSVIKMEIDLLKNL 63 Query: 529 SHPNLVK 549 HPN+VK Sbjct: 64 DHPNIVK 70
>EPHA7_RAT (P54759) Ephrin type-A receptor 7 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) Length = 998 Score = 34.7 bits (78), Expect = 0.18 Identities = 23/70 (32%), Positives = 38/70 (54%), Gaps = 1/70 (1%) Frame = +1 Query: 346 RTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLD-SFQGHKEWLAEVNYLG 522 + + ++G G FG V G R P K + VA+K LK+ + + +++L E + +G Sbjct: 634 KIERVIGAGEFGEVCSG----RLKLPGK--RDVAVAIKTLKVGYTEKQRRDFLCEASIMG 687 Query: 523 QLSHPNLVKL 552 Q HPN+V L Sbjct: 688 QFDHPNVVHL 697
>EPHA7_HUMAN (Q15375) Ephrin type-A receptor 7 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Receptor protein-tyrosine kinase HEK11) Length = 998 Score = 34.7 bits (78), Expect = 0.18 Identities = 23/70 (32%), Positives = 38/70 (54%), Gaps = 1/70 (1%) Frame = +1 Query: 346 RTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLD-SFQGHKEWLAEVNYLG 522 + + ++G G FG V G R P K + VA+K LK+ + + +++L E + +G Sbjct: 634 KIERVIGAGEFGEVCSG----RLKLPGK--RDVAVAIKTLKVGYTEKQRRDFLCEASIMG 687 Query: 523 QLSHPNLVKL 552 Q HPN+V L Sbjct: 688 QFDHPNVVHL 697
>PO2F2_MOUSE (Q00196) POU domain, class 2, transcription factor 2| (Octamer-binding transcription factor 2) (Oct-2) (OTF-2) (Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2) Length = 462 Score = 34.7 bits (78), Expect = 0.18 Identities = 18/51 (35%), Positives = 27/51 (52%), Gaps = 4/51 (7%) Frame = -1 Query: 402 DPPLEDGAEAPLPEQAVSPEVPRATFQLT----EGELAEVGRLQDLLLAPG 262 DP + AP P Q P +P+A LT G++ ++ +LQ L+L PG Sbjct: 66 DPSGDSAPAAPPPPQPAQPHLPQAQLMLTGSQLAGDIQQLLQLQQLVLVPG 116
>KIN4_YEAST (Q01919) Serine/threonine-protein kinase KIN4 (EC 2.7.11.1)| Length = 800 Score = 34.7 bits (78), Expect = 0.18 Identities = 23/70 (32%), Positives = 34/70 (48%), Gaps = 4/70 (5%) Frame = +1 Query: 355 SLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKE----WLAEVNYLG 522 S LGEG FG V GW + V VA+K ++ D+ + + E+N L Sbjct: 50 STLGEGEFGKVKLGWTKASSSNEVPKQ----VAIKLIRRDTIKKDADKEIKIYREINALK 105 Query: 523 QLSHPNLVKL 552 L+HPN++ L Sbjct: 106 HLTHPNIIYL 115
>EGFR_DROME (P04412) Epidermal growth factor receptor precursor (EC 2.7.10.1)| (Egfr) (Gurken receptor) (Protein torpedo) (Drosophila relative of ERBB) Length = 1426 Score = 34.7 bits (78), Expect = 0.18 Identities = 24/71 (33%), Positives = 35/71 (49%), Gaps = 2/71 (2%) Frame = +1 Query: 346 RTDSLLGEGGFGSVFKG-WIDERTFTPVKPGTGMIVAVKK-LKLDSFQGHKEWLAEVNYL 519 R +LG G FG V+KG W+ E + VA+K+ LK + +E+L E + Sbjct: 939 RKGGVLGMGAFGRVYKGVWVPEGENVKIP------VAIKELLKSTGAESSEEFLREAYIM 992 Query: 520 GQLSHPNLVKL 552 H NL+KL Sbjct: 993 ASEEHVNLLKL 1003
>JAK3_RAT (Q63272) Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3)| (JAK-3) Length = 1100 Score = 34.7 bits (78), Expect = 0.18 Identities = 23/71 (32%), Positives = 38/71 (53%) Frame = +1 Query: 337 RNFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEWLAEVNY 516 R+ + SLLG+G FGSV + + P+ TG +VAVK+L+ + +++ E+ Sbjct: 816 RHLKYISLLGKGNFGSV-----ELCRYDPLGDNTGPLVAVKQLQHSGPEQQRDFQREIQI 870 Query: 517 LGQLSHPNLVK 549 L L +VK Sbjct: 871 LKALHCDFIVK 881
>EPHA7_CHICK (O42422) Ephrin type-A receptor 7 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor CEPHA7) (Tyrosine-protein kinase receptor CEK11) Length = 993 Score = 34.7 bits (78), Expect = 0.18 Identities = 23/70 (32%), Positives = 38/70 (54%), Gaps = 1/70 (1%) Frame = +1 Query: 346 RTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLD-SFQGHKEWLAEVNYLG 522 + + ++G G FG V G R P K + VA+K LK+ + + +++L E + +G Sbjct: 629 KIERVIGAGEFGEVCSG----RLKLPGK--RDVAVAIKTLKVGYTEKQRRDFLCEASIMG 682 Query: 523 QLSHPNLVKL 552 Q HPN+V L Sbjct: 683 QFDHPNVVHL 692
>M3K2_ARATH (Q9FZ36) Mitogen-activated protein kinase kinase kinase 2 (EC| 2.7.11.25) (Arabidospsis NPK1-related protein kinase 2) Length = 651 Score = 34.7 bits (78), Expect = 0.18 Identities = 25/77 (32%), Positives = 39/77 (50%), Gaps = 8/77 (10%) Frame = +1 Query: 343 FRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDS-------FQGH-KEW 498 +R L+G G FG+V+ G + +G ++AVK++ + S Q H +E Sbjct: 68 WRKGQLIGRGAFGTVYMG---------MNLDSGELLAVKQVLITSNCASKEKTQAHIQEL 118 Query: 499 LAEVNYLGQLSHPNLVK 549 EV L LSHPN+V+ Sbjct: 119 EEEVKLLKNLSHPNIVR 135
>E2AK2_SCHPO (Q9UTE5) Eukaryotic translation initiation factor 2-alpha kinase 2| (EC 2.7.11.1) (Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase) (Heme-regulated inhibitor 2) Length = 639 Score = 34.7 bits (78), Expect = 0.18 Identities = 29/99 (29%), Positives = 46/99 (46%), Gaps = 14/99 (14%) Frame = +1 Query: 295 NLRKFTFSEL----------KSCTRNFRTDSLLGEGGFGSVF--KGWIDERTFTPVKPGT 438 N+R+F F +L +F SLLG GGFGSV+ + ID Sbjct: 145 NVRQFRFRDLTLESWLQSRNSRYIEDFEEYSLLGRGGFGSVYHVRNKID----------- 193 Query: 439 GMIVAVKKLKLDSFQ--GHKEWLAEVNYLGQLSHPNLVK 549 G A+KK+ +FQ + + E+ L ++ HPN+++ Sbjct: 194 GAEYAMKKIN-STFQQMSYSKIFREIKCLAKMDHPNVIR 231
>TYK2_MOUSE (Q9R117) Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)| Length = 1180 Score = 34.7 bits (78), Expect = 0.18 Identities = 26/64 (40%), Positives = 30/64 (46%), Gaps = 1/64 (1%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLD-SFQGHKEWLAEVNYLGQLSHP 537 LGEG FG V D P GTG +VAVK LK Q W E+ L L H Sbjct: 896 LGEGHFGKVSLYCYD-----PTNDGTGEMVAVKALKEGCGPQLRSGWQREIEILRTLYHE 950 Query: 538 NLVK 549 ++VK Sbjct: 951 HIVK 954
>XMRK_XIPMA (P13388) Melanoma receptor tyrosine-protein kinase precursor (EC| 2.7.10.1) Length = 1167 Score = 34.3 bits (77), Expect = 0.24 Identities = 22/71 (30%), Positives = 38/71 (53%), Gaps = 1/71 (1%) Frame = +1 Query: 343 FRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLK-LDSFQGHKEWLAEVNYL 519 F+ D +LG G FG+V+KG + P + VA+K L+ S + ++E L E + Sbjct: 710 FKKDRVLGSGAFGTVYKG-----LWNPDGENIRIPVAIKVLREATSPKVNQEVLDEAYVM 764 Query: 520 GQLSHPNLVKL 552 + HP++ +L Sbjct: 765 ASVDHPHVCRL 775
>TX13B_HUMAN (Q9BXU2) Testis-expressed sequence 13B protein| Length = 312 Score = 34.3 bits (77), Expect = 0.24 Identities = 40/119 (33%), Positives = 50/119 (42%), Gaps = 4/119 (3%) Frame = -1 Query: 345 EVPRATFQL--TEGELAEVGRLQDLLLAPGSRRHRRRRTLAKSAGVSRITAAALGIVT*G 172 E ATFQL TE LAEV R +D+L R LA G + T G+ T G Sbjct: 121 ECNEATFQLQLTETSLAEVQRERDML-----RWKLFHAELAPPQGQGQATVFP-GLATAG 174 Query: 171 VGSTE--GRVDLGVPLHAGAVPHQERQRYRPVQPEPRGWLESVCCGLGAGARTGVGLAI 1 TE G + AGA + +RY P P L+ GLG G R +G + Sbjct: 175 GDWTEGAGEQEKEAVAAAGAAGGKGEERYAEAGPAPAEVLQ----GLGGGFRQPLGAIV 229
>ROR2_MOUSE (Q9Z138) Tyrosine-protein kinase transmembrane receptor ROR2| precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2) (mROR2) Length = 944 Score = 34.3 bits (77), Expect = 0.24 Identities = 25/66 (37%), Positives = 33/66 (50%), Gaps = 2/66 (3%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQG--HKEWLAEVNYLGQLSH 534 LGE FG V+KG + F P VA+K LK D +G +E+ E +L H Sbjct: 479 LGEDRFGKVYKGHL----FGPAPGEPTQAVAIKTLK-DKAEGPLREEFRQEAMLRARLQH 533 Query: 535 PNLVKL 552 PN+V L Sbjct: 534 PNIVCL 539
>STK3_MOUSE (Q9JI10) Serine/threonine-protein kinase 3 (EC 2.7.11.1)| (STE20-like kinase MST2) (MST-2) (Mammalian STE20-like protein kinase 2) Length = 497 Score = 34.3 bits (77), Expect = 0.24 Identities = 27/94 (28%), Positives = 45/94 (47%), Gaps = 1/94 (1%) Frame = +1 Query: 271 EKEILQSSNLRKFTFSEL-KSCTRNFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMI 447 E+ S L+K + L K F LGEG +GSVFK + +G + Sbjct: 2 EQPPASKSKLKKLSEDSLTKQPEEVFDVLEKLGEGSYGSVFKA---------IHKESGQV 52 Query: 448 VAVKKLKLDSFQGHKEWLAEVNYLGQLSHPNLVK 549 VA+K++ ++S +E + E++ + Q P +VK Sbjct: 53 VAIKQVPVES--DLQEIIKEISIMQQCDSPYVVK 84
>CDKL4_HUMAN (Q5MAI5) Cyclin-dependent kinase-like 4 (EC 2.7.11.22)| Length = 315 Score = 34.3 bits (77), Expect = 0.24 Identities = 28/65 (43%), Positives = 32/65 (49%), Gaps = 2/65 (3%) Frame = +1 Query: 364 GEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKL--KLDSFQGHKEWLAEVNYLGQLSHP 537 GEG +G VFK R T +G +VAVKK D K L E+ L QL HP Sbjct: 11 GEGSYGVVFKC----RNKT-----SGQVVAVKKFVESEDDPVVKKIALREIRMLKQLKHP 61 Query: 538 NLVKL 552 NLV L Sbjct: 62 NLVNL 66
>NEK7_MOUSE (Q9ES74) Serine/threonine-protein kinase Nek7 (EC 2.7.11.1)| (NimA-related protein kinase 7) Length = 302 Score = 34.3 bits (77), Expect = 0.24 Identities = 22/75 (29%), Positives = 39/75 (52%), Gaps = 5/75 (6%) Frame = +1 Query: 340 NFRTDSLLGEGGFGSVFKG--WIDERTFTPVKPGTGMIVAVKKLKLDSFQGHK---EWLA 504 NFR + +G G F V++ +D G+ VA+KK+++ K + + Sbjct: 33 NFRIEKKIGRGQFSEVYRASCLLD-----------GVPVALKKVQIFDLMDAKARADCIK 81 Query: 505 EVNYLGQLSHPNLVK 549 E++ L QL+HPN++K Sbjct: 82 EIDLLKQLNHPNVIK 96
>NEK7_HUMAN (Q8TDX7) Serine/threonine-protein kinase Nek7 (EC 2.7.11.1)| (NimA-related protein kinase 7) Length = 302 Score = 34.3 bits (77), Expect = 0.24 Identities = 22/75 (29%), Positives = 39/75 (52%), Gaps = 5/75 (6%) Frame = +1 Query: 340 NFRTDSLLGEGGFGSVFKG--WIDERTFTPVKPGTGMIVAVKKLKLDSFQGHK---EWLA 504 NFR + +G G F V++ +D G+ VA+KK+++ K + + Sbjct: 33 NFRIEKKIGRGQFSEVYRAACLLD-----------GVPVALKKVQIFDLMDAKARADCIK 81 Query: 505 EVNYLGQLSHPNLVK 549 E++ L QL+HPN++K Sbjct: 82 EIDLLKQLNHPNVIK 96
>SYMM_FUGRU (Q90YI3) Methionyl-tRNA synthetase, mitochondrial precursor (EC| 6.1.1.10) (Methionine--tRNA ligase 2) (Mitochondrial methionine--tRNA ligase) (MtMetRS) Length = 590 Score = 34.3 bits (77), Expect = 0.24 Identities = 19/52 (36%), Positives = 29/52 (55%), Gaps = 4/52 (7%) Frame = +1 Query: 388 FKGWI---DERTFTPVKPGTGMIVAVKKLKLDSFQGHK-EWLAEVNYLGQLS 531 ++GW DE TP + T + K++K+ GHK EW+ E NY+ +LS Sbjct: 161 YEGWYSTQDESFLTPSQVTTALDSTGKEIKVSLESGHKVEWMKEENYMFRLS 212
>SHARK_DROME (Q24145) Tyrosine-protein kinase shark (EC 2.7.10.2)| Length = 939 Score = 34.3 bits (77), Expect = 0.24 Identities = 24/71 (33%), Positives = 35/71 (49%), Gaps = 4/71 (5%) Frame = +1 Query: 352 DSLLGEGGFGSVFKGWIDERTFTPVKPGTG----MIVAVKKLKLDSFQGHKEWLAEVNYL 519 D +G G FGSV GW+ K G G + VA+K L D +E+L E + + Sbjct: 665 DREIGHGEFGSVHSGWLLR------KSGAGEESRLEVAIKMLS-DEHSNKQEFLREASVM 717 Query: 520 GQLSHPNLVKL 552 +L H +V+L Sbjct: 718 MRLEHKCIVRL 728
>CDC15_YEAST (P27636) Cell division control protein 15 (EC 2.7.11.1)| Length = 974 Score = 34.3 bits (77), Expect = 0.24 Identities = 17/69 (24%), Positives = 36/69 (52%) Frame = +1 Query: 343 FRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEWLAEVNYLG 522 + ++G G +G V+K + T +VA+K++ ++ + + +AE++ L Sbjct: 25 YHLKQVIGRGSYGVVYKA---------INKHTDQVVAIKEVVYENDEELNDIMAEISLLK 75 Query: 523 QLSHPNLVK 549 L+H N+VK Sbjct: 76 NLNHNNIVK 84
>CDK9_CAEEL (Q9TVL3) Probable cell division protein kinase 9 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9) Length = 478 Score = 34.3 bits (77), Expect = 0.24 Identities = 25/69 (36%), Positives = 34/69 (49%), Gaps = 5/69 (7%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEW-----LAEVNYLGQ 525 +G+G FG VFK TG +VA+KK+ +++ KE L EV L Q Sbjct: 91 IGQGTFGEVFKARCKN---------TGRMVALKKILMEN---EKEGFPITALREVKMLEQ 138 Query: 526 LSHPNLVKL 552 L HPN+ L Sbjct: 139 LKHPNITDL 147
>SRK3_SPOLA (P42689) Tyrosine-protein kinase SRK3 (EC 2.7.10.2) (Fragment)| Length = 334 Score = 34.3 bits (77), Expect = 0.24 Identities = 24/64 (37%), Positives = 36/64 (56%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEWLAEVNYLGQLSHPN 540 LG+G FG V+ G V GT VAVK LK D+ + K+++ E + ++ HPN Sbjct: 72 LGQGNFGEVWAG---------VWNGT-TAVAVKTLKPDTME-VKDFVQEAQVMKKIHHPN 120 Query: 541 LVKL 552 L++L Sbjct: 121 LLQL 124
>ABL_DROME (P00522) Tyrosine-protein kinase Abl (EC 2.7.10.2) (Abelson| protein) (D-ash) Length = 1620 Score = 34.3 bits (77), Expect = 0.24 Identities = 25/78 (32%), Positives = 37/78 (47%) Frame = +1 Query: 319 ELKSCTRNFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEW 498 E + C + LG G +G V++ V G VAVK LK D+ K++ Sbjct: 363 EWEICRTDIMMKHKLGGGQYGEVYEA---------VWKRYGNTVAVKTLKEDTM-ALKDF 412 Query: 499 LAEVNYLGQLSHPNLVKL 552 L E + ++ HPNLV+L Sbjct: 413 LEEAAIMKEMKHPNLVQL 430
>EGFR_MOUSE (Q01279) Epidermal growth factor receptor precursor (EC 2.7.10.1)| Length = 1210 Score = 34.3 bits (77), Expect = 0.24 Identities = 23/72 (31%), Positives = 39/72 (54%), Gaps = 2/72 (2%) Frame = +1 Query: 343 FRTDSLLGEGGFGSVFKG-WIDERTFTPVKPGTGMIVAVKKLK-LDSFQGHKEWLAEVNY 516 F+ +LG G FG+V+KG WI E + VA+K+L+ S + +KE L E Sbjct: 714 FKKIKVLGSGAFGTVYKGLWIPEGEKVKIP------VAIKELREATSPKANKEILDEAYV 767 Query: 517 LGQLSHPNLVKL 552 + + +P++ +L Sbjct: 768 MASVDNPHVCRL 779
>EGFR_HUMAN (P00533) Epidermal growth factor receptor precursor (EC 2.7.10.1)| (Receptor tyrosine-protein kinase ErbB-1) Length = 1210 Score = 34.3 bits (77), Expect = 0.24 Identities = 23/72 (31%), Positives = 39/72 (54%), Gaps = 2/72 (2%) Frame = +1 Query: 343 FRTDSLLGEGGFGSVFKG-WIDERTFTPVKPGTGMIVAVKKLK-LDSFQGHKEWLAEVNY 516 F+ +LG G FG+V+KG WI E + VA+K+L+ S + +KE L E Sbjct: 712 FKKIKVLGSGAFGTVYKGLWIPEGEKVKIP------VAIKELREATSPKANKEILDEAYV 765 Query: 517 LGQLSHPNLVKL 552 + + +P++ +L Sbjct: 766 MASVDNPHVCRL 777
>ERBB_ALV (P00534) Tyrosine-protein kinase transforming protein erbB (EC| 2.7.10.1) Length = 634 Score = 34.3 bits (77), Expect = 0.24 Identities = 23/72 (31%), Positives = 39/72 (54%), Gaps = 2/72 (2%) Frame = +1 Query: 343 FRTDSLLGEGGFGSVFKG-WIDERTFTPVKPGTGMIVAVKKLK-LDSFQGHKEWLAEVNY 516 F+ +LG G FG+V+KG WI E + VA+K+L+ S + +KE L E Sbjct: 132 FKKVKVLGSGAFGTVYKGLWIPEGEKVKIP------VAIKELREATSPKANKEILDEAYV 185 Query: 517 LGQLSHPNLVKL 552 + + +P++ +L Sbjct: 186 MASVDNPHVCRL 197
>STK3_HUMAN (Q13188) Serine/threonine-protein kinase 3 (EC 2.7.11.1)| (STE20-like kinase MST2) (MST-2) (Mammalian STE20-like protein kinase 2) (Serine/threonine-protein kinase Krs-1) Length = 491 Score = 33.9 bits (76), Expect = 0.31 Identities = 26/87 (29%), Positives = 43/87 (49%), Gaps = 1/87 (1%) Frame = +1 Query: 292 SNLRKFTFSEL-KSCTRNFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLK 468 S L+K + L K F LGEG +GSVFK + +G +VA+K++ Sbjct: 9 SKLKKLSEDSLTKQPEEVFDVLEKLGEGSYGSVFKA---------IHKESGQVVAIKQVP 59 Query: 469 LDSFQGHKEWLAEVNYLGQLSHPNLVK 549 ++S +E + E++ + Q P +VK Sbjct: 60 VES--DLQEIIKEISIMQQCDSPYVVK 84
>ACK1_MOUSE (O54967) Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1)| (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2) Length = 1055 Score = 33.9 bits (76), Expect = 0.31 Identities = 25/75 (33%), Positives = 37/75 (49%), Gaps = 3/75 (4%) Frame = +1 Query: 337 RNFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSF---QGHKEWLAE 507 ++ R LG+G FG V +G D G + VAVK LK D + +++ E Sbjct: 124 KDLRLLEKLGDGSFGVVRRGEWD------APAGKTVSVAVKCLKPDVLSQPEAMDDFIRE 177 Query: 508 VNYLGQLSHPNLVKL 552 VN + L H NL++L Sbjct: 178 VNAMHSLDHRNLIRL 192
>ACK1_HUMAN (Q07912) Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine| kinase non-receptor protein 2) Length = 1036 Score = 33.9 bits (76), Expect = 0.31 Identities = 25/75 (33%), Positives = 38/75 (50%), Gaps = 3/75 (4%) Frame = +1 Query: 337 RNFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSF---QGHKEWLAE 507 ++ R LG+G FG V +G D + G + VAVK LK D + +++ E Sbjct: 124 KDLRLLEKLGDGSFGVVRRGEWDAPS------GKTVSVAVKCLKPDVLSQPEAMDDFIRE 177 Query: 508 VNYLGQLSHPNLVKL 552 VN + L H NL++L Sbjct: 178 VNAMHSLDHRNLIRL 192
>LCK_HUMAN (P06239) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) (T cell-specific protein-tyrosine kinase) Length = 508 Score = 33.9 bits (76), Expect = 0.31 Identities = 25/64 (39%), Positives = 31/64 (48%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEWLAEVNYLGQLSHPN 540 LG G FG V+ G+ + T VAVK LK S +LAE N + QL H Sbjct: 250 LGAGQFGEVWMGYYNGHTK----------VAVKSLKQGSMSPDA-FLAEANLMKQLQHQR 298 Query: 541 LVKL 552 LV+L Sbjct: 299 LVRL 302
>EPHA7_MOUSE (Q61772) Ephrin type-A receptor 7 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Embryonic brain kinase) (EBK) (Developmental kinase 1) (MDK-1) Length = 998 Score = 33.9 bits (76), Expect = 0.31 Identities = 22/71 (30%), Positives = 38/71 (53%), Gaps = 2/71 (2%) Frame = +1 Query: 346 RTDSLLGEGGFGSVFKGWIDERTFTPVKPGT-GMIVAVKKLKLD-SFQGHKEWLAEVNYL 519 + + ++G G FG V G + PG + VA+K LK+ + + +++L E + + Sbjct: 634 KIERVIGAGEFGEVCSGRLK-------LPGQRDVAVAIKTLKVGYTEKQRRDFLCEASIM 686 Query: 520 GQLSHPNLVKL 552 GQ HPN+V L Sbjct: 687 GQFDHPNVVHL 697
>EPHB5_CHICK (Q07497) Ephrin type-B receptor 5 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase CEK9) Length = 1002 Score = 33.9 bits (76), Expect = 0.31 Identities = 22/73 (30%), Positives = 39/73 (53%), Gaps = 4/73 (5%) Frame = +1 Query: 346 RTDSLLGEGGFGSVFKGWID---ERTFTPVKPGTGMIVAVKKLKLD-SFQGHKEWLAEVN 513 + + ++G G FG V G + +R +T VA+K LK + + +E+L+E + Sbjct: 638 KIEEVIGSGEFGEVCFGRLKHPGKREYT---------VAIKTLKSGYTDEQRREFLSEAS 688 Query: 514 YLGQLSHPNLVKL 552 +GQ HPN++ L Sbjct: 689 IMGQFEHPNVIHL 701
>TYRO3_HUMAN (Q06418) Tyrosine-protein kinase receptor TYRO3 precursor (EC| 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase SKY) (Tyrosine-protein kinase DTK) (Protein-tyrosine kinase byk) Length = 890 Score = 33.9 bits (76), Expect = 0.31 Identities = 23/74 (31%), Positives = 38/74 (51%), Gaps = 2/74 (2%) Frame = +1 Query: 337 RNFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGH--KEWLAEV 510 + F +LG+G FGSV + + + + G+ + VAVK LK D +E+L E Sbjct: 516 QQFTLGRMLGKGEFGSVREAQLKQ------EDGSFVKVAVKMLKADIIASSDIEEFLREA 569 Query: 511 NYLGQLSHPNLVKL 552 + + HP++ KL Sbjct: 570 ACMKEFDHPHVAKL 583
>MAK_MOUSE (Q04859) Serine/threonine-protein kinase MAK (EC 2.7.11.22) (Male| germ cell-associated kinase) (Protein kinase RCK) Length = 622 Score = 33.9 bits (76), Expect = 0.31 Identities = 23/71 (32%), Positives = 38/71 (53%), Gaps = 1/71 (1%) Frame = +1 Query: 343 FRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEW-LAEVNYL 519 + T LG+G +GSV G +E +G +VA+K++K + + L EV L Sbjct: 4 YTTMKQLGDGTYGSVLMGKSNE---------SGELVAIKRMKRKFYSWDECMNLREVKSL 54 Query: 520 GQLSHPNLVKL 552 +L+H N++KL Sbjct: 55 KKLNHANVIKL 65
>KC47_ORYSA (P29620) CDC2+/CDC28-related protein kinase R2 (EC 2.7.11.22)| Length = 424 Score = 33.9 bits (76), Expect = 0.31 Identities = 22/67 (32%), Positives = 35/67 (52%), Gaps = 2/67 (2%) Frame = +1 Query: 358 LLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEW--LAEVNYLGQLS 531 +LGEG +G VFK V TG VA+KK++L ++ + L E+ L +L Sbjct: 24 VLGEGTYGVVFKA---------VDTKTGNTVAIKKIRLGKYKEGVNFTALREIKLLKELK 74 Query: 532 HPNLVKL 552 N+++L Sbjct: 75 DSNIIEL 81
>IKKB_RAT (Q9QY78) Inhibitor of nuclear factor kappa B kinase beta subunit| (EC 2.7.11.1) (I-kappa-B-kinase beta) (IkBKB) (IKK-beta) (IKK-B) (I-kappa-B kinase 2) (IKK2) (Nuclear factor NF-kappa-B inhibitor kinase beta) (NFKBIKB) Length = 757 Score = 33.9 bits (76), Expect = 0.31 Identities = 20/63 (31%), Positives = 35/63 (55%), Gaps = 1/63 (1%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLD-SFQGHKEWLAEVNYLGQLSHP 537 LG GGFG+V + W ++ T G +A+K+ + + S + W E+ + +L+HP Sbjct: 21 LGTGGFGNVIR-WHNQVT--------GEQIAIKQCRQELSPKNRDRWCLEIQIMRRLNHP 71 Query: 538 NLV 546 N+V Sbjct: 72 NVV 74
>ERBB_AVIER (P00535) Tyrosine-protein kinase transforming protein erbB (EC| 2.7.10.1) Length = 604 Score = 33.9 bits (76), Expect = 0.31 Identities = 22/72 (30%), Positives = 39/72 (54%), Gaps = 2/72 (2%) Frame = +1 Query: 343 FRTDSLLGEGGFGSVFKG-WIDERTFTPVKPGTGMIVAVKKLK-LDSFQGHKEWLAEVNY 516 F+ +LG G FG+++KG WI E + VA+K+L+ S + +KE L E Sbjct: 132 FKKVKVLGSGAFGTIYKGLWIPEGEKVKIP------VAIKELREATSPKANKEILDEAYV 185 Query: 517 LGQLSHPNLVKL 552 + + +P++ +L Sbjct: 186 MASVDNPHVCRL 197
>TYRO3_RAT (P55146) Tyrosine-protein kinase receptor TYRO3 precursor (EC| 2.7.10.1) (Tyrosine-protein kinase SKY) Length = 880 Score = 33.9 bits (76), Expect = 0.31 Identities = 23/74 (31%), Positives = 38/74 (51%), Gaps = 2/74 (2%) Frame = +1 Query: 337 RNFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGH--KEWLAEV 510 + F +LG+G FGSV + + + + G+ + VAVK LK D +E+L E Sbjct: 506 QQFTLGRMLGKGEFGSVREAQLKQ------EDGSFVKVAVKMLKADIIASSDIEEFLREA 559 Query: 511 NYLGQLSHPNLVKL 552 + + HP++ KL Sbjct: 560 ACMKEFDHPHVAKL 573
>TYRO3_MOUSE (P55144) Tyrosine-protein kinase receptor TYRO3 precursor (EC| 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase DTK) (TK19-2) (Etk2/tyro3) Length = 880 Score = 33.9 bits (76), Expect = 0.31 Identities = 23/74 (31%), Positives = 38/74 (51%), Gaps = 2/74 (2%) Frame = +1 Query: 337 RNFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGH--KEWLAEV 510 + F +LG+G FGSV + + + + G+ + VAVK LK D +E+L E Sbjct: 506 QQFTLGRMLGKGEFGSVREAQLKQ------EDGSFVKVAVKMLKADIIASSDIEEFLREA 559 Query: 511 NYLGQLSHPNLVKL 552 + + HP++ KL Sbjct: 560 ACMKEFDHPHVAKL 573
>CDKL1_RAT (Q66HE7) Cyclin-dependent kinase-like 1 (EC 2.7.11.22)| Length = 352 Score = 33.9 bits (76), Expect = 0.31 Identities = 26/66 (39%), Positives = 32/66 (48%), Gaps = 2/66 (3%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKL--KLDSFQGHKEWLAEVNYLGQLSH 534 +GEG +G VFK + TG IVA+K+ D K L E+ L QL H Sbjct: 10 IGEGSYGVVFKCRNRD---------TGQIVAIKRFLETEDDPVIKKIALREIRMLKQLKH 60 Query: 535 PNLVKL 552 PNLV L Sbjct: 61 PNLVSL 66
>CDKL1_MOUSE (Q8CEQ0) Cyclin-dependent kinase-like 1 (EC 2.7.11.22)| Length = 352 Score = 33.9 bits (76), Expect = 0.31 Identities = 26/66 (39%), Positives = 32/66 (48%), Gaps = 2/66 (3%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKL--KLDSFQGHKEWLAEVNYLGQLSH 534 +GEG +G VFK + TG IVA+K+ D K L E+ L QL H Sbjct: 10 IGEGSYGVVFKCRNRD---------TGQIVAIKRFLETEDDPVIKKIALREIRMLKQLKH 60 Query: 535 PNLVKL 552 PNLV L Sbjct: 61 PNLVNL 66
>ICK_RAT (Q62726) Serine/threonine-protein kinase ICK (EC 2.7.11.22)| (Intestinal cell kinase) (MAK-related kinase) (MRK) Length = 629 Score = 33.9 bits (76), Expect = 0.31 Identities = 24/71 (33%), Positives = 37/71 (52%), Gaps = 1/71 (1%) Frame = +1 Query: 343 FRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEW-LAEVNYL 519 + T LG+G +GSV G E +G ++A+KK+K + + L EV L Sbjct: 4 YTTIKQLGDGTYGSVLLGRSIE---------SGELIAIKKMKRKFYSWEECMNLREVKSL 54 Query: 520 GQLSHPNLVKL 552 +L+H N+VKL Sbjct: 55 KKLNHANIVKL 65
>ICK_MOUSE (Q9JKV2) Serine/threonine-protein kinase ICK (EC 2.7.11.22)| (Intestinal cell kinase) (mICK) (MAK-related kinase) (MRK) Length = 629 Score = 33.9 bits (76), Expect = 0.31 Identities = 24/71 (33%), Positives = 37/71 (52%), Gaps = 1/71 (1%) Frame = +1 Query: 343 FRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEW-LAEVNYL 519 + T LG+G +GSV G E +G ++A+KK+K + + L EV L Sbjct: 4 YTTIKQLGDGTYGSVLLGRSIE---------SGELIAIKKMKRKFYSWEECMNLREVKSL 54 Query: 520 GQLSHPNLVKL 552 +L+H N+VKL Sbjct: 55 KKLNHANIVKL 65
>ABL2_HUMAN (P42684) Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine| leukemia viral oncogene homolog 2) (Tyrosine kinase ARG) Length = 1182 Score = 33.9 bits (76), Expect = 0.31 Identities = 23/64 (35%), Positives = 35/64 (54%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEWLAEVNYLGQLSHPN 540 LG G +G V+ G + + T VAVK LK D+ + +E+L E + ++ HPN Sbjct: 294 LGGGQYGEVYVGVWKKYSLT---------VAVKTLKEDTMEV-EEFLKEAAVMKEIKHPN 343 Query: 541 LVKL 552 LV+L Sbjct: 344 LVQL 347
>EPHA5_MOUSE (Q60629) Ephrin type-A receptor 5 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Brain-specific kinase) (CEK-7) Length = 877 Score = 33.5 bits (75), Expect = 0.41 Identities = 21/69 (30%), Positives = 37/69 (53%), Gaps = 2/69 (2%) Frame = +1 Query: 352 DSLLGEGGFGSVFKGWIDERTFTPVKPGTGMI-VAVKKLKLD-SFQGHKEWLAEVNYLGQ 525 + ++G G FG V G + PG + VA+K LK+ + + +++L E + +GQ Sbjct: 517 ERVIGAGEFGEVCSGCLK-------LPGKRELPVAIKTLKVGYTEKQRRDFLGEASIMGQ 569 Query: 526 LSHPNLVKL 552 HPN++ L Sbjct: 570 FDHPNIIHL 578
>IKKE_HUMAN (Q14164) Inhibitor of nuclear factor kappa-B kinase epsilon subunit| (EC 2.7.11.1) (I kappa-B kinase epsilon) (IkBKE) (IKK-epsilon) (IKK-E) (Inducible I kappa-B kinase) (IKK-i) Length = 716 Score = 33.5 bits (75), Expect = 0.41 Identities = 24/71 (33%), Positives = 35/71 (49%), Gaps = 1/71 (1%) Frame = +1 Query: 343 FRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKE-WLAEVNYL 519 + TD LLG+G SV+K +G +VAVK S+ +E + E L Sbjct: 9 WHTDDLLGQGATASVYKA---------RNKKSGELVAVKVFNTTSYLRPREVQVREFEVL 59 Query: 520 GQLSHPNLVKL 552 +L+H N+VKL Sbjct: 60 RKLNHQNIVKL 70
>EPHA5_HUMAN (P54756) Ephrin type-A receptor 5 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Receptor protein-tyrosine kinase HEK7) Length = 1037 Score = 33.5 bits (75), Expect = 0.41 Identities = 22/68 (32%), Positives = 37/68 (54%), Gaps = 1/68 (1%) Frame = +1 Query: 352 DSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLD-SFQGHKEWLAEVNYLGQL 528 + ++G G FG V G R P K + VA+K LK+ + + +++L E + +GQ Sbjct: 678 ERVIGAGEFGEVCSG----RLKLPGK--RELPVAIKTLKVGYTEKQRRDFLGEASIMGQF 731 Query: 529 SHPNLVKL 552 HPN++ L Sbjct: 732 DHPNIIHL 739
>CRK1_LEIME (Q06309) Cell division protein kinase 2 homolog CRK1 (EC 2.7.11.23)| Length = 301 Score = 33.5 bits (75), Expect = 0.41 Identities = 23/75 (30%), Positives = 36/75 (48%), Gaps = 2/75 (2%) Frame = +1 Query: 334 TRNFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEWLA--E 507 T + +GEG +G V+K T VA+K+++LDS + A E Sbjct: 2 TSRYERQEKIGEGTYGVVYKAR---------DTSTAATVALKRIRLDSEEEGVPCTAIRE 52 Query: 508 VNYLGQLSHPNLVKL 552 ++ L +L H N+VKL Sbjct: 53 ISLLKELRHENIVKL 67
>ROR2_HUMAN (Q01974) Tyrosine-protein kinase transmembrane receptor ROR2| precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2) Length = 943 Score = 33.5 bits (75), Expect = 0.41 Identities = 25/66 (37%), Positives = 33/66 (50%), Gaps = 2/66 (3%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQG--HKEWLAEVNYLGQLSH 534 LGE FG V+KG + F P VA+K LK D +G +E+ E +L H Sbjct: 479 LGEDRFGKVYKGHL----FGPAPGEQTQAVAIKTLK-DKAEGPLREEFRHEAMLRARLQH 533 Query: 535 PNLVKL 552 PN+V L Sbjct: 534 PNVVCL 539
>TAO1A_XENLA (Q6NU21) Serine/threonine-protein kinase TAO1-A (EC 2.7.11.1)| (Thousand and one amino acid protein 1-A) Length = 1001 Score = 33.5 bits (75), Expect = 0.41 Identities = 18/66 (27%), Positives = 33/66 (50%), Gaps = 3/66 (4%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEW---LAEVNYLGQLS 531 +G G FG+V+ T +VA+KK+ Q +++W + EV +L ++ Sbjct: 34 IGHGSFGAVYFAH---------DASTREVVAIKKMSYSGKQSNEKWQDIVKEVKFLQRIK 84 Query: 532 HPNLVK 549 HPN ++ Sbjct: 85 HPNSIE 90
>MAK_RAT (P20793) Serine/threonine-protein kinase MAK (EC 2.7.11.22) (Male| germ cell-associated kinase) Length = 622 Score = 33.5 bits (75), Expect = 0.41 Identities = 23/71 (32%), Positives = 38/71 (53%), Gaps = 1/71 (1%) Frame = +1 Query: 343 FRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEW-LAEVNYL 519 + T LG+G +GSV G +E +G +VA+K++K + + L EV L Sbjct: 4 YTTMRQLGDGTYGSVLMGKSNE---------SGELVAIKRMKRKFYSWDECMNLREVKSL 54 Query: 520 GQLSHPNLVKL 552 +L+H N++KL Sbjct: 55 KKLNHANVIKL 65
>NTRK1_RAT (P35739) High affinity nerve growth factor receptor precursor (EC| 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (p140-TrkA) (Slow nerve growth factor receptor) (Trk-A) Length = 799 Score = 33.5 bits (75), Expect = 0.41 Identities = 21/63 (33%), Positives = 30/63 (47%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEWLAEVNYLGQLSHPN 540 LGEG FG VF + + M+VAVK LK S +++ E L L H + Sbjct: 519 LGEGAFGKVFLA----ECYNLLNDQDKMLVAVKALKETSENARQDFHREAELLTMLQHQH 574 Query: 541 LVK 549 +V+ Sbjct: 575 IVR 577
>EPA4A_BRARE (O13148) Ephrin type-A receptor 4a (EC 2.7.10.1) (Tyrosine-protein| kinase receptor ZEK2) (EPH-like kinase 2) (Fragment) Length = 292 Score = 33.5 bits (75), Expect = 0.41 Identities = 22/66 (33%), Positives = 36/66 (54%), Gaps = 2/66 (3%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMI-VAVKKLKLD-SFQGHKEWLAEVNYLGQLSH 534 +G G FG V G + PG I VA+K LK + + +++L+E + +GQ H Sbjct: 1 IGIGEFGEVCSGRLK-------MPGKREICVAIKTLKAGYTDKQRRDFLSEASIMGQFDH 53 Query: 535 PNLVKL 552 PN+++L Sbjct: 54 PNIIRL 59
>CDC2_CAEEL (P34556) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) Length = 332 Score = 33.5 bits (75), Expect = 0.41 Identities = 23/66 (34%), Positives = 35/66 (53%), Gaps = 2/66 (3%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEWLA--EVNYLGQLSH 534 +GEG +G V+KG T +VA+KK++L+S A E++ L +L H Sbjct: 28 IGEGTYGVVYKG---------KNRRTNAMVAMKKIRLESEDEGVPSTAVREISLLKELQH 78 Query: 535 PNLVKL 552 PN+V L Sbjct: 79 PNVVGL 84
>MAK_HUMAN (P20794) Serine/threonine-protein kinase MAK (EC 2.7.11.22) (Male| germ cell-associated kinase) Length = 623 Score = 33.5 bits (75), Expect = 0.41 Identities = 23/71 (32%), Positives = 38/71 (53%), Gaps = 1/71 (1%) Frame = +1 Query: 343 FRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEW-LAEVNYL 519 + T LG+G +GSV G +E +G +VA+K++K + + L EV L Sbjct: 4 YTTMRQLGDGTYGSVLMGKSNE---------SGELVAIKRMKRKFYSWDECMNLREVKSL 54 Query: 520 GQLSHPNLVKL 552 +L+H N++KL Sbjct: 55 KKLNHANVIKL 65
>CDC2_DROME (P23572) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) Length = 297 Score = 33.5 bits (75), Expect = 0.41 Identities = 24/73 (32%), Positives = 37/73 (50%), Gaps = 2/73 (2%) Frame = +1 Query: 340 NFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQG--HKEWLAEVN 513 +F +GEG +G V+KG TG IVA+KK++L+S + E++ Sbjct: 3 DFEKIEKIGEGTYGVVYKGR---------NRLTGQIVAMKKIRLESDDEGVPSTAIREIS 53 Query: 514 YLGQLSHPNLVKL 552 L +L H N+V L Sbjct: 54 LLKELKHENIVCL 66
>ACK2_BOVIN (O02742) Activated CDC42 kinase 2 (EC 2.7.10.2) (ACK-2)| Length = 747 Score = 33.5 bits (75), Expect = 0.41 Identities = 24/67 (35%), Positives = 35/67 (52%), Gaps = 3/67 (4%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSF---QGHKEWLAEVNYLGQLS 531 LG+G FG V +G D + G + VAVK LK D + +++ EVN + L Sbjct: 132 LGDGSFGVVRRGEWDAPS------GKTVSVAVKCLKPDVLSQPEAMDDFIREVNAMHSLD 185 Query: 532 HPNLVKL 552 H NL++L Sbjct: 186 HRNLIRL 192
>HIPK4_HUMAN (Q8NE63) Homeodomain-interacting protein kinase 4 (EC 2.7.11.1)| Length = 616 Score = 33.5 bits (75), Expect = 0.41 Identities = 20/56 (35%), Positives = 31/56 (55%) Frame = +1 Query: 316 SELKSCTRNFRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQ 483 S ++S T + +LG+G FG V KGW + TG +VA+K LK D+++ Sbjct: 2 STIQSETDCYDIIEVLGKGTFGEVAKGW---------RRSTGEMVAIKILKNDAYR 48
>ICK_HUMAN (Q9UPZ9) Serine/threonine-protein kinase ICK (EC 2.7.11.22)| (Intestinal cell kinase) (hICK) (MAK-related kinase) (MRK) (Laryngeal cancer kinase 2) (LCK2) Length = 632 Score = 33.1 bits (74), Expect = 0.54 Identities = 24/71 (33%), Positives = 37/71 (52%), Gaps = 1/71 (1%) Frame = +1 Query: 343 FRTDSLLGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEW-LAEVNYL 519 + T LG+G +GSV G E +G ++A+KK+K + + L EV L Sbjct: 4 YTTIRQLGDGTYGSVLLGRSIE---------SGELIAIKKMKRKFYSWEECMNLREVKSL 54 Query: 520 GQLSHPNLVKL 552 +L+H N+VKL Sbjct: 55 KKLNHANVVKL 65
>ROR1_HUMAN (Q01973) Tyrosine-protein kinase transmembrane receptor ROR1| precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1) Length = 937 Score = 33.1 bits (74), Expect = 0.54 Identities = 22/69 (31%), Positives = 35/69 (50%), Gaps = 5/69 (7%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGT--GMIVAVKKLKLDSFQGHKEWLA---EVNYLGQ 525 LGE FG ++KG + PG +VA+K LK + ++W+ E + + + Sbjct: 479 LGECAFGKIYKGHL-------YLPGMDHAQLVAIKTLK--DYNNPQQWMEFQQEASLMAE 529 Query: 526 LSHPNLVKL 552 L HPN+V L Sbjct: 530 LHHPNIVCL 538
>TAOK2_MOUSE (Q6ZQ29) Serine/threonine-protein kinase TAO2 (EC 2.7.11.1)| (Thousand and one amino acid protein 2) Length = 1055 Score = 33.1 bits (74), Expect = 0.54 Identities = 20/66 (30%), Positives = 34/66 (51%), Gaps = 3/66 (4%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEW---LAEVNYLGQLS 531 +G G FG+V+ D R +VA+KK+ Q +++W + EV +L +L Sbjct: 34 IGHGSFGAVYFAR-DVRN--------SEVVAIKKMSYSGKQSNEKWQDIIKEVRFLQKLR 84 Query: 532 HPNLVK 549 HPN ++ Sbjct: 85 HPNTIQ 90
>BMPR2_HUMAN (Q13873) Bone morphogenetic protein receptor type-2 precursor (EC| 2.7.11.30) (Bone morphogenetic protein receptor type II) (BMP type II receptor) (BMPR-II) Length = 1038 Score = 33.1 bits (74), Expect = 0.54 Identities = 17/46 (36%), Positives = 26/46 (56%) Frame = +1 Query: 274 KEILQSSNLRKFTFSELKSCTRNFRTDSLLGEGGFGSVFKGWIDER 411 K+ L S N+ + SE N + L+G G +G+V+KG +DER Sbjct: 180 KQGLHSMNMMEAAASEPSLDLDNLKLLELIGRGRYGAVYKGSLDER 225
>TAOK1_RAT (O88664) Serine/threonine-protein kinase TAO1 (EC 2.7.11.1)| (Thousand and one amino acid protein 1) Length = 1001 Score = 33.1 bits (74), Expect = 0.54 Identities = 20/66 (30%), Positives = 34/66 (51%), Gaps = 3/66 (4%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEW---LAEVNYLGQLS 531 +G G FG+V+ D RT +VA+KK+ Q ++W + EV +L ++ Sbjct: 34 IGHGSFGAVYFAR-DVRT--------NEVVAIKKMSYSGKQSTEKWQDIIKEVKFLQRIK 84 Query: 532 HPNLVK 549 HPN ++ Sbjct: 85 HPNSIE 90
>TAOK1_MOUSE (Q5F2E8) Serine/threonine-protein kinase TAO1 (EC 2.7.11.1)| (Thousand and one amino acid protein 1) Length = 1001 Score = 33.1 bits (74), Expect = 0.54 Identities = 20/66 (30%), Positives = 34/66 (51%), Gaps = 3/66 (4%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEW---LAEVNYLGQLS 531 +G G FG+V+ D RT +VA+KK+ Q ++W + EV +L ++ Sbjct: 34 IGHGSFGAVYFAR-DVRT--------NEVVAIKKMSYSGKQSTEKWQDIIKEVKFLQRIK 84 Query: 532 HPNLVK 549 HPN ++ Sbjct: 85 HPNSIE 90
>TAOK1_HUMAN (Q7L7X3) Serine/threonine-protein kinase TAO1 (EC 2.7.11.1)| (Thousand and one amino acid protein 1) (STE20-like kinase PSK2) (Kinase from chicken homolog B) (hKFC-B) Length = 1001 Score = 33.1 bits (74), Expect = 0.54 Identities = 20/66 (30%), Positives = 34/66 (51%), Gaps = 3/66 (4%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEW---LAEVNYLGQLS 531 +G G FG+V+ D RT +VA+KK+ Q ++W + EV +L ++ Sbjct: 34 IGHGSFGAVYFAR-DVRT--------NEVVAIKKMSYSGKQSTEKWQDIIKEVKFLQRIK 84 Query: 532 HPNLVK 549 HPN ++ Sbjct: 85 HPNSIE 90
>ERBB_AVIEU (P11273) Tyrosine-protein kinase transforming protein erbB (EC| 2.7.10.1) Length = 540 Score = 33.1 bits (74), Expect = 0.54 Identities = 23/72 (31%), Positives = 39/72 (54%), Gaps = 2/72 (2%) Frame = +1 Query: 343 FRTDSLLGEGGFGSVFKG-WIDERTFTPVKPGTGMIVAVKKLK-LDSFQGHKEWLAEVNY 516 F+ +LG G FG+V+KG WI E + VA+K+L+ S + +KE L E Sbjct: 132 FKKVKVLGFGAFGTVYKGLWIPEGEKVTIP------VAIKELREATSPKANKEILDEAYV 185 Query: 517 LGQLSHPNLVKL 552 + + +P++ +L Sbjct: 186 MASVDNPHVCRL 197
>TAOK2_RAT (Q9JLS3) Serine/threonine-protein kinase TAO2 (EC 2.7.11.1)| (Thousand and one amino acid protein 2) Length = 1235 Score = 33.1 bits (74), Expect = 0.54 Identities = 20/66 (30%), Positives = 34/66 (51%), Gaps = 3/66 (4%) Frame = +1 Query: 361 LGEGGFGSVFKGWIDERTFTPVKPGTGMIVAVKKLKLDSFQGHKEW---LAEVNYLGQLS 531 +G G FG+V+ D R +VA+KK+ Q +++W + EV +L +L Sbjct: 34 IGHGSFGAVYFAR-DVRN--------SEVVAIKKMSYSGKQSNEKWQDIIKEVRFLQKLR 84 Query: 532 HPNLVK 549 HPN ++ Sbjct: 85 HPNTIQ 90 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 74,784,694 Number of Sequences: 219361 Number of extensions: 1590592 Number of successful extensions: 9144 Number of sequences better than 10.0: 453 Number of HSP's better than 10.0 without gapping: 7916 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 8884 length of database: 80,573,946 effective HSP length: 105 effective length of database: 57,541,041 effective search space used: 4488201198 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
