>DLL1_HUMAN (O00548) Delta-like protein 1 precursor (Drosophila Delta homolog|
           1) (Delta1) (H-Delta-1)
          Length = 723

 Score = 34.3 bits (77), Expect = 0.19
 Identities = 22/82 (26%), Positives = 30/82 (36%)
 Frame = +2

Query: 212 CASGAQQRSATCATSGHACLXXXXXXXXXXXXXXXXXXXSSTPTSPVVTCQGWIWECSRT 391
           C+S      A C   G A L                   +S+P +   TC+  + + S T
Sbjct: 409 CSSSPCSNGAKCVDLGDAYLCRCQAGFSGRHCDDNVDDCASSPCANGGTCRDGVNDFSCT 468

Query: 392 CPGSATGRAPNWPTRRCSAVRC 457
           CP   TGR  + P  RC    C
Sbjct: 469 CPPGYTGRNCSAPVSRCEHAPC 490

>DLL1_RAT (P97677) Delta-like protein 1 precursor (Drosophila Delta homolog|
           1) (Delta1)
          Length = 714

 Score = 33.5 bits (75), Expect = 0.33
 Identities = 21/82 (25%), Positives = 31/82 (37%)
 Frame = +2

Query: 212 CASGAQQRSATCATSGHACLXXXXXXXXXXXXXXXXXXXSSTPTSPVVTCQGWIWECSRT 391
           C+S      A C   G++ L                   +S+P +   TC+  + + S T
Sbjct: 408 CSSSPCSNGAKCVDLGNSYLCRCQTGFSGRYCEDNVDDCASSPCANGGTCRDSVNDFSCT 467

Query: 392 CPGSATGRAPNWPTRRCSAVRC 457
           CP   TGR  + P  RC    C
Sbjct: 468 CPPGYTGRNCSAPVSRCEHAPC 489

>PRIO_BOSTR (Q5UJG7) Major prion protein precursor (PrP) (CD230 antigen)|
          Length = 264

 Score = 33.5 bits (75), Expect = 0.33
 Identities = 19/60 (31%), Positives = 20/60 (33%)
 Frame = -1

Query: 448 GTAPPCGPIWRSPCRGSWACP*ALPNPSLACNHGRGWR*RAQQHGSGHWRWRPATGSWRQ 269
           G   P G  W  P  G W  P           HG GW    Q HG G W      G W +
Sbjct: 67  GWGQPHGGSWGQPHGGGWGQP-----------HGGGW---GQPHGGGGWGQGGTHGQWNK 112

>PRIO_TRAIM (Q5UJG3) Major prion protein precursor (PrP) (CD230 antigen)|
          Length = 264

 Score = 32.7 bits (73), Expect = 0.56
 Identities = 19/60 (31%), Positives = 20/60 (33%)
 Frame = -1

Query: 448 GTAPPCGPIWRSPCRGSWACP*ALPNPSLACNHGRGWR*RAQQHGSGHWRWRPATGSWRQ 269
           G   P G  W  P  G W  P           HG GW    Q HG G W      G W +
Sbjct: 67  GWGQPHGGGWGQPHGGGWGQP-----------HGGGW---GQPHGGGGWGQGGTHGQWNK 112

>PRIO_BOSIN (Q5UJI7) Major prion protein precursor (PrP) (CD230 antigen)|
          Length = 264

 Score = 32.7 bits (73), Expect = 0.56
 Identities = 19/60 (31%), Positives = 20/60 (33%)
 Frame = -1

Query: 448 GTAPPCGPIWRSPCRGSWACP*ALPNPSLACNHGRGWR*RAQQHGSGHWRWRPATGSWRQ 269
           G   P G  W  P  G W  P           HG GW    Q HG G W      G W +
Sbjct: 67  GWGQPHGGGWGQPHGGGWGQP-----------HGGGW---GQPHGGGGWGQGGTHGQWNK 112

>PRIO_BOSGA (Q5UJH0) Major prion protein precursor (PrP) (CD230 antigen)|
          Length = 264

 Score = 32.7 bits (73), Expect = 0.56
 Identities = 19/60 (31%), Positives = 20/60 (33%)
 Frame = -1

Query: 448 GTAPPCGPIWRSPCRGSWACP*ALPNPSLACNHGRGWR*RAQQHGSGHWRWRPATGSWRQ 269
           G   P G  W  P  G W  P           HG GW    Q HG G W      G W +
Sbjct: 67  GWGQPHGGGWGQPHGGGWGQP-----------HGGGW---GQPHGGGGWGQGGTHGQWNK 112

>PRIO_BISBI (Q5UAF1) Major prion protein precursor (PrP) (CD230 antigen)|
          Length = 264

 Score = 32.7 bits (73), Expect = 0.56
 Identities = 19/60 (31%), Positives = 20/60 (33%)
 Frame = -1

Query: 448 GTAPPCGPIWRSPCRGSWACP*ALPNPSLACNHGRGWR*RAQQHGSGHWRWRPATGSWRQ 269
           G   P G  W  P  G W  P           HG GW    Q HG G W      G W +
Sbjct: 67  GWGQPHGGGWGQPHGGGWGQP-----------HGGGW---GQPHGGGGWGQGGTHGQWNK 112

>PRIO_AILME (Q6EH52) Major prion protein precursor (PrP) (CD230 antigen)|
          Length = 264

 Score = 32.7 bits (73), Expect = 0.56
 Identities = 19/60 (31%), Positives = 20/60 (33%)
 Frame = -1

Query: 448 GTAPPCGPIWRSPCRGSWACP*ALPNPSLACNHGRGWR*RAQQHGSGHWRWRPATGSWRQ 269
           G   P G  W  P  G W  P           HG GW    Q HG G W      G W +
Sbjct: 67  GWGQPHGGGWGQPHGGGWGQP-----------HGGGW---GQPHGGGGWGQGGTHGQWNK 112

>PRIO1_TRAST (P40242) Major prion protein 1 precursor (PrP) (Major|
           scrapie-associated fibril protein 1) (CD230 antigen)
          Length = 264

 Score = 32.7 bits (73), Expect = 0.56
 Identities = 19/60 (31%), Positives = 20/60 (33%)
 Frame = -1

Query: 448 GTAPPCGPIWRSPCRGSWACP*ALPNPSLACNHGRGWR*RAQQHGSGHWRWRPATGSWRQ 269
           G   P G  W  P  G W  P           HG GW    Q HG G W      G W +
Sbjct: 67  GWGQPHGGGWGQPHGGGWGQP-----------HGGGW---GQPHGGGGWGQGGTHGQWNK 112

>PRIO1_BOVIN (P10279) Major prion protein 1 precursor (PrP) (Major|
           scrapie-associated fibril protein 1) (CD230 antigen)
          Length = 264

 Score = 32.7 bits (73), Expect = 0.56
 Identities = 19/60 (31%), Positives = 20/60 (33%)
 Frame = -1

Query: 448 GTAPPCGPIWRSPCRGSWACP*ALPNPSLACNHGRGWR*RAQQHGSGHWRWRPATGSWRQ 269
           G   P G  W  P  G W  P           HG GW    Q HG G W      G W +
Sbjct: 67  GWGQPHGGGWGQPHGGGWGQP-----------HGGGW---GQPHGGGGWGQGGTHGQWNK 112

>DLL1_MOUSE (Q61483) Delta-like protein 1 precursor (Drosophila Delta homolog|
           1) (Delta1)
          Length = 722

 Score = 32.0 bits (71), Expect = 0.95
 Identities = 20/82 (24%), Positives = 30/82 (36%)
 Frame = +2

Query: 212 CASGAQQRSATCATSGHACLXXXXXXXXXXXXXXXXXXXSSTPTSPVVTCQGWIWECSRT 391
           C S      A C   G++ L                   +S+P +   TC+  + + S T
Sbjct: 408 CGSSPCSNGAKCVDLGNSYLCRCQAGFSGRYCEDNVDDCASSPCANGGTCRDSVNDFSCT 467

Query: 392 CPGSATGRAPNWPTRRCSAVRC 457
           CP   TG+  + P  RC    C
Sbjct: 468 CPPGYTGKNCSAPVSRCEHAPC 489

>PRIO2_TRAST (P40243) Major prion protein 2 precursor (PrP) (Major|
           scrapie-associated fibril protein 2) (CD230 antigen)
          Length = 256

 Score = 31.2 bits (69), Expect = 1.6
 Identities = 18/56 (32%), Positives = 19/56 (33%)
 Frame = -1

Query: 436 PCGPIWRSPCRGSWACP*ALPNPSLACNHGRGWR*RAQQHGSGHWRWRPATGSWRQ 269
           P G  W  P  G W  P           HG GW    Q HG G W      G W +
Sbjct: 63  PHGGGWGQPHVGGWGQP-----------HGGGW---GQPHGGGGWGQGGTHGQWNK 104

>PRIO_SAISC (P40258) Major prion protein precursor (PrP) (PrP27-30) (PrP33-35C)|
           (CD230 antigen)
          Length = 260

 Score = 31.2 bits (69), Expect = 1.6
 Identities = 21/57 (36%), Positives = 22/57 (38%)
 Frame = -1

Query: 439 PPCGPIWRSPCRGSWACP*ALPNPSLACNHGRGWR*RAQQHGSGHWRWRPATGSWRQ 269
           PP G  W  P  G W  P           HG GW    Q HG G W  +P  G W Q
Sbjct: 50  PPQGGGWGQPHGGGWGQP-----------HGGGW---GQPHGGG-W-GQPHGGGWGQ 90

>PRIO_RABIT (Q95211) Major prion protein precursor (PrP) (PrP27-30) (PrP33-35C)|
           (CD230 antigen)
          Length = 252

 Score = 31.2 bits (69), Expect = 1.6
 Identities = 21/57 (36%), Positives = 22/57 (38%)
 Frame = -1

Query: 439 PPCGPIWRSPCRGSWACP*ALPNPSLACNHGRGWR*RAQQHGSGHWRWRPATGSWRQ 269
           PP G  W  P  G W  P           HG GW    Q HG G W  +P  G W Q
Sbjct: 51  PPQGGGWGQPHGGGWGQP-----------HGGGW---GQPHGGG-W-GQPHGGGWGQ 91

>PRIO_CALJA (P40247) Major prion protein precursor (PrP) (PrP27-30) (PrP33-35C)|
           (CD230 antigen)
          Length = 252

 Score = 31.2 bits (69), Expect = 1.6
 Identities = 21/57 (36%), Positives = 22/57 (38%)
 Frame = -1

Query: 439 PPCGPIWRSPCRGSWACP*ALPNPSLACNHGRGWR*RAQQHGSGHWRWRPATGSWRQ 269
           PP G  W  P  G W  P           HG GW    Q HG G W  +P  G W Q
Sbjct: 50  PPQGGGWGQPHGGGWGQP-----------HGGGW---GQPHGGG-W-GQPHGGGWGQ 90

>PRIO_ATEPA (P51446) Major prion protein precursor (PrP) (PrP27-30) (PrP33-35C)|
           (CD230 antigen)
          Length = 252

 Score = 31.2 bits (69), Expect = 1.6
 Identities = 21/57 (36%), Positives = 22/57 (38%)
 Frame = -1

Query: 439 PPCGPIWRSPCRGSWACP*ALPNPSLACNHGRGWR*RAQQHGSGHWRWRPATGSWRQ 269
           PP G  W  P  G W  P           HG GW    Q HG G W  +P  G W Q
Sbjct: 50  PPQGGGWGQPHGGGWGQP-----------HGGGW---GQPHGGG-W-GQPHGGGWGQ 90

>PRIO_CEBAP (P40249) Major prion protein precursor (PrP) (PrP27-30) (PrP33-35C)|
           (CD230 antigen)
          Length = 252

 Score = 30.8 bits (68), Expect = 2.1
 Identities = 21/57 (36%), Positives = 22/57 (38%)
 Frame = -1

Query: 439 PPCGPIWRSPCRGSWACP*ALPNPSLACNHGRGWR*RAQQHGSGHWRWRPATGSWRQ 269
           PP G  W  P  G W  P           HG GW    Q HG G W  +P  G W Q
Sbjct: 50  PPQGGGWGQPHGGGWGQP-----------HGGGW---GQPHG-GSW-GQPHGGGWGQ 90

>RX_HUMAN (Q9Y2V3) Retinal homeobox protein Rx (Retina and anterior neural|
           fold homeobox protein)
          Length = 346

 Score = 30.0 bits (66), Expect = 3.6
 Identities = 17/45 (37%), Positives = 20/45 (44%)
 Frame = -1

Query: 475 PCRLIEASHGTAPPCGPIWRSPCRGSWACP*ALPNPSLACNHGRG 341
           P + + AS+   PP  P   SP  G    P A P PS  C  G G
Sbjct: 266 PAQSLPASYTPPPPPPPFLNSPPLGPGLQPLAPPPPSYPCGPGFG 310

>CYSZ_SALTY (P12673) Protein cysZ|
          Length = 253

 Score = 29.6 bits (65), Expect = 4.7
 Identities = 20/49 (40%), Positives = 26/49 (53%), Gaps = 1/49 (2%)
 Frame = +1

Query: 286 WLAATANGRSHAAALVNANLSRGYMPGMD-LGVLKDMPRIRDRASAKLA 429
           W+AA  NG    A  + A L+    P    LG++KD+PRI  R   KLA
Sbjct: 98  WIAAPFNGL--LAEQLEARLTGATPPDTGILGIMKDVPRIMKREWQKLA 144

>CYSZ_SALTI (Q8Z4W3) Protein cysZ|
          Length = 253

 Score = 29.6 bits (65), Expect = 4.7
 Identities = 20/49 (40%), Positives = 26/49 (53%), Gaps = 1/49 (2%)
 Frame = +1

Query: 286 WLAATANGRSHAAALVNANLSRGYMPGMD-LGVLKDMPRIRDRASAKLA 429
           W+AA  NG    A  + A L+    P    LG++KD+PRI  R   KLA
Sbjct: 98  WIAAPFNGL--LAEQLEARLTGATPPDTGILGIMKDVPRIMKREWQKLA 144

>CYSZ_SALPA (Q5PND3) Protein cysZ|
          Length = 253

 Score = 29.6 bits (65), Expect = 4.7
 Identities = 20/49 (40%), Positives = 26/49 (53%), Gaps = 1/49 (2%)
 Frame = +1

Query: 286 WLAATANGRSHAAALVNANLSRGYMPGMD-LGVLKDMPRIRDRASAKLA 429
           W+AA  NG    A  + A L+    P    LG++KD+PRI  R   KLA
Sbjct: 98  WIAAPFNGL--LAEQLEARLTGATPPDTGILGIMKDVPRIMKREWQKLA 144

>PRIO_MOUSE (P04925) Major prion protein precursor (PrP) (PrP27-30) (PrP33-35C)|
           (CD230 antigen)
          Length = 254

 Score = 29.6 bits (65), Expect = 4.7
 Identities = 20/57 (35%), Positives = 21/57 (36%)
 Frame = -1

Query: 439 PPCGPIWRSPCRGSWACP*ALPNPSLACNHGRGWR*RAQQHGSGHWRWRPATGSWRQ 269
           PP G  W  P  G W  P           HG  W    Q HG G W  +P  G W Q
Sbjct: 50  PPQGGTWGQPHGGGWGQP-----------HGGSW---GQPHG-GSW-GQPHGGGWGQ 90

>KYK1_DICDI (P18160) Non-receptor tyrosine kinase spore lysis A (EC 2.7.10.2)|
           (Tyrosine-protein kinase 1)
          Length = 1584

 Score = 29.3 bits (64), Expect = 6.2
 Identities = 19/54 (35%), Positives = 32/54 (59%), Gaps = 3/54 (5%)
 Frame = -3

Query: 497 SDTAQTISL*ADRSI-SRHCTSL--WANLALALSRILGMSLSTPKSIPGM*PRE 345
           ++++ T+S+  + ++  RHC SL   A+    LS  LG+S S+P S P   PR+
Sbjct: 632 NNSSSTLSVGGNNNLLGRHCQSLPITASTNHTLSSSLGVSFSSPSSSPKTSPRK 685

>IASPP_MOUSE (Q5I1X5) RelA-associated inhibitor (Inhibitor of ASPP protein)|
           (Protein iASPP) (PPP1R13B-like protein)
           (NFkB-interacting protein 1)
          Length = 824

 Score = 28.9 bits (63), Expect = 8.1
 Identities = 16/40 (40%), Positives = 18/40 (45%)
 Frame = +3

Query: 336 RQPLPWLHARDGFGSAQGHAQDPRQGERQIGPQGGAVP*D 455
           R P P   A DG GS  G A  PR G   +   G + P D
Sbjct: 137 RAPSPRPRAFDGAGSPHGRAPSPRPGIGPVRQPGPSTPFD 176


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 70,241,010
Number of Sequences: 219361
Number of extensions: 1364843
Number of successful extensions: 3818
Number of sequences better than 10.0: 24
Number of HSP's better than 10.0 without gapping: 3669
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3815
length of database: 80,573,946
effective HSP length: 104
effective length of database: 57,760,402
effective search space used: 3581144924
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)