ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | basd24k23 |
|---|---|
| Clone Library Name | barley_pub |
>PHOT1_ARATH (O48963) Phototropin-1 (EC 2.7.11.1) (Non-phototropic hypocotyl| protein 1) (Root phototropism protein 1) Length = 996 Score = 248 bits (633), Expect = 1e-65 Identities = 118/187 (63%), Positives = 145/187 (77%), Gaps = 4/187 (2%) Frame = +1 Query: 28 ACLTSCRPQVFLP--EEANXXXXXXXXXXPIFFAEPMRASNSFVGTEEYIAPEIITGAGH 201 +CLTSC+PQ+ +P +E PIF AEPMRASNSFVGTEEYIAPEII+GAGH Sbjct: 810 SCLTSCKPQLLIPSIDEKKKKKQQKSQQTPIFMAEPMRASNSFVGTEEYIAPEIISGAGH 869 Query: 202 TSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLL 381 TSAVDWWALGIL+YEMLYGYTPFRGKTRQ+TF N+L KD++FPASI SL +QLI+RLL Sbjct: 870 TSAVDWWALGILMYEMLYGYTPFRGKTRQKTFTNVLQKDLKFPASIPASLQVKQLIFRLL 929 Query: 382 HRDPANRMGSYEGSNEIKQHPFFRGINWALVRGTAPPKLDAPLFSKDV--GKGMGDAAAA 555 RDP R+G +EG+NE+KQH FF+GINWAL+R T PP+L+ P+FS + G+ + D Sbjct: 930 QRDPKKRLGCFEGANEVKQHSFFKGINWALIRCTNPPELETPIFSGEAENGEKVVDPELE 989 Query: 556 DNGTDMF 576 D T++F Sbjct: 990 DLQTNVF 996
>PHOT2_ARATH (P93025) Phototropin-2 (EC 2.7.11.1) (Defective in chloroplast| avoidance protein 1) (Non phototropic hypocotyl 1-like protein 1) (NPH1-like 1) (AtKin7) Length = 915 Score = 229 bits (584), Expect = 6e-60 Identities = 112/177 (63%), Positives = 130/177 (73%) Frame = +1 Query: 34 LTSCRPQVFLPEEANXXXXXXXXXXPIFFAEPMRASNSFVGTEEYIAPEIITGAGHTSAV 213 +T+C PQ+ +P + P F AEP SNSFVGTEEYIAPEIITGAGHTSA+ Sbjct: 726 MTTCTPQLIIPAAPSKRRRSKSQPLPTFVAEPSTQSNSFVGTEEYIAPEIITGAGHTSAI 785 Query: 214 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 393 DWWALGILLYEMLYG TPFRGK RQ+TFANILHKD+ FP+SI VSL RQLI LL+RDP Sbjct: 786 DWWALGILLYEMLYGRTPFRGKNRQKTFANILHKDLTFPSSIPVSLVGRQLINTLLNRDP 845 Query: 394 ANRMGSYEGSNEIKQHPFFRGINWALVRGTAPPKLDAPLFSKDVGKGMGDAAAADNG 564 ++R+GS G+NEIKQH FFRGINW L+RG +PP LDAPL + D D+G Sbjct: 846 SSRLGSKGGANEIKQHAFFRGINWPLIRGMSPPPLDAPLSIIEKDPNAKDIKWEDDG 902
>KAD5_SCHPO (Q09831) Probable serine/threonine-protein kinase C4G8.05 (EC| 2.7.11.1) Length = 566 Score = 154 bits (388), Expect = 3e-37 Identities = 72/121 (59%), Positives = 90/121 (74%), Gaps = 3/121 (2%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKD 318 +NSFVGTEEYIAPE+I G GHTSAVDWW LGIL YEMLY TPF+GK R TF+NILHKD Sbjct: 379 TNSFVGTEEYIAPEVIKGCGHTSAVDWWTLGILFYEMLYATTPFKGKNRNMTFSNILHKD 438 Query: 319 IRFPA---SISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINWALVRGTAP 489 + FP + S+S + LI +LL +D +R+GS G+ ++K HPFF+ + WAL+R T P Sbjct: 439 VIFPEYADAPSISSLCKNLIRKLLVKDENDRLGSQAGAADVKLHPFFKNVQWALLRHTEP 498 Query: 490 P 492 P Sbjct: 499 P 499
>KPK7_ARATH (Q05999) Putative serine/threonine-protein kinase PK7 (EC 2.7.11.1)| Length = 578 Score = 150 bits (380), Expect = 3e-36 Identities = 73/139 (52%), Positives = 94/139 (67%), Gaps = 1/139 (0%) Frame = +1 Query: 109 PIFFAEPMRA-SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTR 285 P AEP A S SFVGT EY+APEII G GH SAVDWW GI LYE+L+G TPFRG Sbjct: 402 PELIAEPTSARSMSFVGTHEYLAPEIIKGEGHGSAVDWWTFGIFLYELLFGITPFRGGDN 461 Query: 286 QRTFANILHKDIRFPASISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINW 465 + T N++ + +RFP +VS AR LI LL ++P +R+ G+ EIKQHPFF+ +NW Sbjct: 462 RATLFNVVGQPLRFPEHPNVSFAARDLIRGLLVKEPQHRLAYRRGATEIKQHPFFQSVNW 521 Query: 466 ALVRGTAPPKLDAPLFSKD 522 AL+R T+PP++ P+ D Sbjct: 522 ALIRCTSPPQIPQPVKPMD 540
>NRC2_NEUCR (O42626) Serine/threonine-protein kinase nrc-2 (EC 2.7.11.1)| (Nonrepressible conidiation protein 2) Length = 623 Score = 150 bits (379), Expect = 4e-36 Identities = 72/121 (59%), Positives = 89/121 (73%), Gaps = 3/121 (2%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKD 318 +NSFVGTEEYIAPE+I G+GHTSAVDWW LGIL+YEMLYG TPF+GK R TFANIL +D Sbjct: 426 TNSFVGTEEYIAPEVIKGSGHTSAVDWWTLGILIYEMLYGTTPFKGKNRNATFANILRED 485 Query: 319 IRFP---ASISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINWALVRGTAP 489 I FP + +S + LI +LL +D R+G+ G+++IK HPFFR WAL+R P Sbjct: 486 IPFPDHAGAPQISNLCKSLIRKLLIKDENRRLGARAGASDIKTHPFFRTTQWALIRHMKP 545 Query: 490 P 492 P Sbjct: 546 P 546
>KPK1_PHAVU (P15792) Protein kinase PVPK-1 (EC 2.7.11.1)| Length = 609 Score = 150 bits (378), Expect = 5e-36 Identities = 74/146 (50%), Positives = 96/146 (65%), Gaps = 6/146 (4%) Frame = +1 Query: 109 PIFFAEPMRA-SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTR 285 P AEP A S SFVGT EY+APEII G GH SAVDWW GI LYE+L+G TPF+G Sbjct: 451 PELIAEPTNARSMSFVGTHEYLAPEIIKGEGHGSAVDWWTFGIFLYELLFGRTPFKGSAN 510 Query: 286 QRTFANILHKDIRFPASISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINW 465 + T N++ + +RFP S +VS AR LI LL ++P +R+ G+ EIKQHPFF+ +NW Sbjct: 511 RATLFNVIGQPLRFPESPTVSFAARDLIRGLLVKEPQHRLAYRRGATEIKQHPFFQNVNW 570 Query: 466 ALVRGTAPPK-----LDAPLFSKDVG 528 AL+R PP+ ++ P KD+G Sbjct: 571 ALIRCATPPEVPRQVINLPQTEKDLG 596
>G11A_ORYSA (P47997) Protein kinase G11A (EC 2.7.11.1)| Length = 589 Score = 149 bits (377), Expect = 6e-36 Identities = 72/135 (53%), Positives = 91/135 (67%), Gaps = 1/135 (0%) Frame = +1 Query: 109 PIFFAEPMRA-SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTR 285 P AEP A S SFVGT EY+APEII G GH SAVDWW GI LYE+L+G TPF+G Sbjct: 419 PELIAEPSDARSMSFVGTHEYLAPEIIKGEGHGSAVDWWTFGIFLYELLFGKTPFKGSGN 478 Query: 286 QRTFANILHKDIRFPASISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINW 465 + T N++ + +RFP VS AR LI LL ++P R+G G+ EIKQHPFF G+NW Sbjct: 479 RATLFNVIGQPLRFPEYPVVSFSARDLIRGLLVKEPQQRLGCKRGATEIKQHPFFEGVNW 538 Query: 466 ALVRGTAPPKLDAPL 510 AL+R +PP++ P+ Sbjct: 539 ALIRCASPPEVPRPV 553
>KIN82_YEAST (P25341) Probable serine/threonine-protein kinase KIN82 (EC| 2.7.11.1) Length = 720 Score = 149 bits (376), Expect = 8e-36 Identities = 66/122 (54%), Positives = 90/122 (73%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKD 318 +NSFVGTEEY+APE+I G GHT+AVDWW LGIL+YEML+G TPF+G TF+NIL KD Sbjct: 499 TNSFVGTEEYLAPEVIRGNGHTAAVDWWTLGILIYEMLFGCTPFKGDNSNETFSNILTKD 558 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINWALVRGTAPPKL 498 ++FP VS + LI +LL+++ A R+GS G+ +IK+HPFF+ + W+ +R PP + Sbjct: 559 VKFPHDKEVSKNCKDLIKKLLNKNEAKRLGSKSGAADIKRHPFFKKVQWSFLRNQDPPLI 618 Query: 499 DA 504 A Sbjct: 619 PA 620
>KN8R_YEAST (P53739) Probable serine/threonine-protein kinase YNR047W (EC| 2.7.11.1) Length = 893 Score = 145 bits (366), Expect = 1e-34 Identities = 64/128 (50%), Positives = 92/128 (71%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKD 318 +NSFVGTEEYIAPE+I G GHT+AVDWW LGIL+YEML+G+TPF+G TF NIL + Sbjct: 674 TNSFVGTEEYIAPEVIRGNGHTAAVDWWTLGILIYEMLFGFTPFKGDNTNETFTNILKNE 733 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINWALVRGTAPPKL 498 + FP + +S + LI +LL ++ + R+G G+ ++K+HPFF+ + W+L+R PP + Sbjct: 734 VSFPNNNEISRTCKDLIKKLLTKNESKRLGCKMGAADVKKHPFFKKVQWSLLRNQEPPLI 793 Query: 499 DAPLFSKD 522 P+ S+D Sbjct: 794 --PVLSED 799
>CEK1_SCHPO (P38938) Serine/threonine-protein kinase cek1 (EC 2.7.11.1)| Length = 1338 Score = 114 bits (284), Expect = 4e-25 Identities = 59/137 (43%), Positives = 81/137 (59%), Gaps = 2/137 (1%) Frame = +1 Query: 118 FAEPMRASNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTF 297 F E S F+GT +YIAPE+I G A DWW+LG +++E L+GY PF +T + F Sbjct: 847 FFENKDPSKRFIGTPDYIAPEVILGNPGIKASDWWSLGCVVFEFLFGYPPFNAETPDQVF 906 Query: 298 ANILHKDIRFPASI--SVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINWAL 471 NIL + I +PA + + S A LI RLL +PANR+G+ G EIK HPFF+ +NW Sbjct: 907 QNILARRINWPAEVFTAESSVALDLIDRLLCMNPANRLGA-NGVEEIKAHPFFKSVNWDT 965 Query: 472 VRGTAPPKLDAPLFSKD 522 + PP + P +D Sbjct: 966 ILEEDPPFVPKPFSPED 982
>YPK1_YEAST (P12688) Serine/threonine-protein kinase YPK1 (EC 2.7.11.1)| Length = 680 Score = 107 bits (267), Expect = 4e-23 Identities = 55/130 (42%), Positives = 79/130 (60%), Gaps = 2/130 (1%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKD 318 +++F GT EY+APE++ G G+T AVDWW LG+LLYEML G P+ + + + IL + Sbjct: 502 TDTFCGTPEYLAPELLLGLGYTKAVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQEP 561 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINW--ALVRGTAPP 492 + FP A+ L+ LL RDP R+G Y G++EI+ HPFF ++W L++G PP Sbjct: 562 LVFPDGF--DRDAKDLLIGLLSRDPTRRLG-YNGADEIRNHPFFSQLSWKRLLMKGYIPP 618 Query: 493 KLDAPLFSKD 522 A S D Sbjct: 619 YKPAVSNSMD 628
>PKN1_MOUSE (P70268) Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protein| kinase C-like 1) (Protein-kinase C-related kinase 1) (Protein kinase C-like PKN) (Serine-threonine protein kinase N) Length = 946 Score = 106 bits (264), Expect = 8e-23 Identities = 51/121 (42%), Positives = 78/121 (64%), Gaps = 3/121 (2%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKD 318 +++F GT E++APE++T +T AVDWW LG+LLYEML G +PF G + F +I++ + Sbjct: 776 TSTFCGTPEFLAPEVLTDTSYTRAVDWWGLGVLLYEMLVGESPFPGDDEEEVFDSIVNDE 835 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMGSYE-GSNEIKQHPFFRGINW--ALVRGTAP 489 +R+P +S A ++ RLL R+P R+GS E + ++K+ PFFR + W L R P Sbjct: 836 VRYPRFLSAE--AIGIMRRLLRRNPERRLGSTERDAEDVKKQPFFRSLGWDVLLARRLPP 893 Query: 490 P 492 P Sbjct: 894 P 894
>PKN2_HUMAN (Q16513) Serine/threonine-protein kinase N2 (EC 2.7.11.13) (Protein| kinase C-like 2) (Protein-kinase C-related kinase 2) Length = 984 Score = 105 bits (263), Expect = 1e-22 Identities = 47/111 (42%), Positives = 77/111 (69%), Gaps = 1/111 (0%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKD 318 +++F GT E++APE++T +T AVDWW LG+L+YEML G +PF G + F +I++ + Sbjct: 814 TSTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDE 873 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMGSYE-GSNEIKQHPFFRGINWA 468 +R+P +S A ++ RLL R+P R+G+ E + ++K+HPFFR I+W+ Sbjct: 874 VRYPRFLSTE--AISIMRRLLRRNPERRLGASEKDAEDVKKHPFFRLIDWS 922
>PKN1_HUMAN (Q16512) Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protein| kinase C-like 1) (Protein-kinase C-related kinase 1) (Protein kinase C-like PKN) (Serine-threonine protein kinase N) (Protein kinase PKN-alpha) Length = 942 Score = 105 bits (263), Expect = 1e-22 Identities = 51/120 (42%), Positives = 79/120 (65%), Gaps = 2/120 (1%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKD 318 +++F GT E++APE++T +T AVDWW LG+LLYEML G +PF G + F +I++ + Sbjct: 772 TSTFCGTPEFLAPEVLTDTSYTRAVDWWGLGVLLYEMLVGESPFPGDDEEEVFDSIVNDE 831 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMGSYE-GSNEIKQHPFFRGINW-ALVRGTAPP 492 +R+P +S A ++ RLL R+P R+GS E + ++K+ PFFR + W AL+ PP Sbjct: 832 VRYPRFLSAE--AIGIMRRLLRRNPERRLGSSERDAEDVKKQPFFRTLGWEALLARRLPP 889
>KS6B1_RAT (P67999) Ribosomal protein S6 kinase beta-1 (EC 2.7.11.1)| (Ribosomal protein S6 kinase I) (S6K) (p70-S6K) Length = 525 Score = 105 bits (262), Expect = 1e-22 Identities = 54/121 (44%), Positives = 78/121 (64%), Gaps = 3/121 (2%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKD 318 +++F GT EY+APEI+ +GH AVDWW+LG L+Y+ML G PF G+ R++T IL Sbjct: 250 THTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCK 309 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMGSYEG-SNEIKQHPFFRGINW--ALVRGTAP 489 + P ++ AR L+ +LL R+ A+R+G+ G + E++ HPFFR INW L R P Sbjct: 310 LNLPPYLTQE--ARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEELLARKVEP 367 Query: 490 P 492 P Sbjct: 368 P 368
>KS6B1_RABIT (P67998) Ribosomal protein S6 kinase beta-1 (EC 2.7.11.1)| (Ribosomal protein S6 kinase I) (S6K) (p70-S6K) Length = 525 Score = 105 bits (262), Expect = 1e-22 Identities = 54/121 (44%), Positives = 78/121 (64%), Gaps = 3/121 (2%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKD 318 +++F GT EY+APEI+ +GH AVDWW+LG L+Y+ML G PF G+ R++T IL Sbjct: 250 THTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCK 309 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMGSYEG-SNEIKQHPFFRGINW--ALVRGTAP 489 + P ++ AR L+ +LL R+ A+R+G+ G + E++ HPFFR INW L R P Sbjct: 310 LNLPPYLTQE--ARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEELLARKVEP 367 Query: 490 P 492 P Sbjct: 368 P 368
>KS6B1_MOUSE (Q8BSK8) Ribosomal protein S6 kinase beta-1 (EC 2.7.11.1)| (Ribosomal protein S6 kinase I) (S6K) (p70-S6K) Length = 525 Score = 105 bits (262), Expect = 1e-22 Identities = 54/121 (44%), Positives = 78/121 (64%), Gaps = 3/121 (2%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKD 318 +++F GT EY+APEI+ +GH AVDWW+LG L+Y+ML G PF G+ R++T IL Sbjct: 250 THTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCK 309 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMGSYEG-SNEIKQHPFFRGINW--ALVRGTAP 489 + P ++ AR L+ +LL R+ A+R+G+ G + E++ HPFFR INW L R P Sbjct: 310 LNLPPYLTQE--ARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEELLARKVEP 367 Query: 490 P 492 P Sbjct: 368 P 368
>KS6B1_HUMAN (P23443) Ribosomal protein S6 kinase beta-1 (EC 2.7.11.1)| (Ribosomal protein S6 kinase I) (S6K) (S6K1) (70 kDa ribosomal protein S6 kinase 1) (p70 S6 kinase alpha) (p70(S6K)-alpha) (p70-S6K) (p70-alpha) Length = 525 Score = 105 bits (262), Expect = 1e-22 Identities = 54/121 (44%), Positives = 78/121 (64%), Gaps = 3/121 (2%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKD 318 +++F GT EY+APEI+ +GH AVDWW+LG L+Y+ML G PF G+ R++T IL Sbjct: 250 THTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCK 309 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMGSYEG-SNEIKQHPFFRGINW--ALVRGTAP 489 + P ++ AR L+ +LL R+ A+R+G+ G + E++ HPFFR INW L R P Sbjct: 310 LNLPPYLTQE--ARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEELLARKVEP 367 Query: 490 P 492 P Sbjct: 368 P 368
>YPK2_YEAST (P18961) Serine/threonine-protein kinase YPK2/YKR2 (EC 2.7.11.1)| Length = 677 Score = 105 bits (261), Expect = 2e-22 Identities = 52/120 (43%), Positives = 76/120 (63%), Gaps = 2/120 (1%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKD 318 +++F GT EY+APEI+ G G+T VDWW LGILLYEM+ G P+ + + IL + Sbjct: 499 TDTFCGTPEYLAPEILLGQGYTKTVDWWTLGILLYEMMTGLPPYYDENVPVMYKKILQQP 558 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINW--ALVRGTAPP 492 + FP + A+ L+ LL RDP+ R+G G++EI+ HPFF+ I+W L++G PP Sbjct: 559 LLFPDGFDPA--AKDLLIGLLSRDPSRRLG-VNGTDEIRNHPFFKDISWKKLLLKGYIPP 615
>PKN1_RAT (Q63433) Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protein| kinase C-like 1) (Protein-kinase C-related kinase 1) (Protein kinase C-like PKN) (Serine-threonine protein kinase N) (Protease-activated kinase 1) (PAK-1) Length = 946 Score = 104 bits (260), Expect = 2e-22 Identities = 50/120 (41%), Positives = 79/120 (65%), Gaps = 2/120 (1%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKD 318 +++F GT E++APE++T +T AVDWW LG+ LYEML G +PF G + F +I++ + Sbjct: 776 TSTFCGTPEFLAPEVLTDTSYTRAVDWWGLGVFLYEMLVGESPFPGDDEEEVFDSIVNDE 835 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMGSYE-GSNEIKQHPFFRGINW-ALVRGTAPP 492 +R+P +S A ++ RLL R+P R+GS E + ++K+ PFFR ++W AL+ PP Sbjct: 836 VRYPRFLSAE--AIGIMRRLLRRNPERRLGSTERDAEDVKKQPFFRTLDWDALLARRLPP 893
>CBK1_YEAST (P53894) Serine/threonine-protein kinase CBK1 (EC 2.7.11.1) (Cell| wall biosynthesis kinase) Length = 756 Score = 104 bits (259), Expect = 3e-22 Identities = 53/119 (44%), Positives = 74/119 (62%), Gaps = 3/119 (2%) Frame = +1 Query: 145 SFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILH--KD 318 S VGT +YIAPEI G+ DWW+LG ++YE L G+ PF +T Q T+ I++ + Sbjct: 570 STVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQT 629 Query: 319 IRFPASISVSLPARQLIYRLL-HRDPANRMGSYEGSNEIKQHPFFRGINWALVRGTAPP 492 ++FP I +S A LI RLL H D R+G + G++EIK HPFFRG++W +R P Sbjct: 630 LQFPDDIHISYEAEDLIRRLLTHAD--QRLGRHGGADEIKSHPFFRGVDWNTIRQVEAP 686
>KS6A2_MOUSE (Q9WUT3) Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1)| (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (Protein-tyrosine kinase Mpk-9) (MAP kinase-activated protein kinase 1c) (M Length = 733 Score = 104 bits (259), Expect = 3e-22 Identities = 50/108 (46%), Positives = 70/108 (64%), Gaps = 1/108 (0%) Frame = +1 Query: 145 SFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIR 324 SF GT EY+APE++ GHT + DWW+ G+L++EML G PF+GK R+ T A IL + Sbjct: 218 SFCGTIEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAKLG 277 Query: 325 FPASISVSLPARQLIYRLLHRDPANRMGS-YEGSNEIKQHPFFRGINW 465 P +S A+ L+ L R+P NR+G+ +G EIK+HPFF I+W Sbjct: 278 MPQFLSAE--AQSLLRALFKRNPCNRLGAGVDGVEEIKRHPFFVTIDW 323 Score = 59.7 bits (143), Expect = 8e-09 Identities = 39/119 (32%), Positives = 62/119 (52%), Gaps = 9/119 (7%) Frame = +1 Query: 118 FAEPMRASNSFVGTEEY----IAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRG--- 276 FA+ +RA N + T Y +APE++ G+ +A D W+LGILLY ML G+TPF Sbjct: 557 FAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDAACDVWSLGILLYTMLAGFTPFANGPD 616 Query: 277 KTRQRTFANILHKDIRFPAS--ISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPF 447 T + A I S+S A+ ++ ++LH DP R+ + ++ +HP+ Sbjct: 617 DTPEEILARIGSGKYALSGGNWDSISDAAKDVVSKMLHVDPQQRLTAV----QVLKHPW 671
>PKN2_RAT (O08874) Serine/threonine-protein kinase N2 (EC 2.7.11.13) (Protein| kinase C-like 2) (Protein-kinase C-related kinase 2) (Protease-activated kinase 2) (PAK-2) (Fragment) Length = 842 Score = 103 bits (258), Expect = 4e-22 Identities = 49/121 (40%), Positives = 80/121 (66%), Gaps = 3/121 (2%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKD 318 +++F GT E++APE++T +T AVDWW LG+L+YEML G +PF G + F +I++ + Sbjct: 678 TSTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDE 737 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMGSYE-GSNEIKQHPFFRGINWA--LVRGTAP 489 +R+P +S A ++ RLL R+P R+G+ E + ++K+HPFFR +W+ L + P Sbjct: 738 VRYPRFLSTE--AISIMRRLLRRNPERRLGAGEKDAEDVKKHPFFRLTDWSALLDKKVKP 795 Query: 490 P 492 P Sbjct: 796 P 796
>KS6AA_CHICK (P18652) Ribosomal protein S6 kinase 2 alpha (EC 2.7.11.1)| (Ribosomal protein S6 kinase II alpha) (S6KII-alpha) (P90-RSK) (MAP kinase-activated protein kinase 1) (MAPK-activated protein kinase 1) (MAPKAP kinase 1) (MAPKAPK-1) Length = 752 Score = 103 bits (257), Expect = 5e-22 Identities = 49/108 (45%), Positives = 71/108 (65%), Gaps = 1/108 (0%) Frame = +1 Query: 145 SFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIR 324 SF GT EY+APE++ GH+ + DWW+ G+L++EML G PF+GK R+ T IL + Sbjct: 239 SFCGTVEYMAPEVVNRQGHSHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLG 298 Query: 325 FPASISVSLPARQLIYRLLHRDPANRMGS-YEGSNEIKQHPFFRGINW 465 P +S A+ L+ L R+PANR+GS +G+ EIK+HPF+ I+W Sbjct: 299 MPQFLSAE--AQSLLRALFKRNPANRLGSGPDGAEEIKRHPFYSTIDW 344 Score = 55.5 bits (132), Expect = 2e-07 Identities = 39/120 (32%), Positives = 61/120 (50%), Gaps = 10/120 (8%) Frame = +1 Query: 118 FAEPMRASNSFVGTEEY----IAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTR 285 FA+ +RA N + T Y +APE++ G+ D W+LG+LLY ML G TPF Sbjct: 577 FAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDEGCDIWSLGVLLYTMLAGCTPFANGPS 636 Query: 286 QRTFANILHKDIRFPASI------SVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPF 447 T IL + S+ ++S A+ L+ ++LH DP R+ + ++ QHP+ Sbjct: 637 D-TPEEILTRIGGGKFSVNGGNWDTISDVAKDLVSKMLHVDPHQRL----TAKQVLQHPW 691
>PKN2_MOUSE (Q8BWW9) Serine/threonine-protein kinase N2 (EC 2.7.11.13) (Protein| kinase C-like 2) (Protein-kinase C-related kinase 2) Length = 983 Score = 103 bits (257), Expect = 5e-22 Identities = 46/111 (41%), Positives = 76/111 (68%), Gaps = 1/111 (0%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKD 318 +++F GT E++APE++T +T AVDWW LG+L+YEML G +PF G + F +I++ + Sbjct: 813 TSTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDE 872 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMGSYE-GSNEIKQHPFFRGINWA 468 +R+P +S A ++ RLL R+P R+G+ E + ++K+HPFFR +W+ Sbjct: 873 VRYPRFLSTE--AISIMRRLLRRNPERRLGAGEKDAEDVKKHPFFRLTDWS 921
>KS6A2_HUMAN (Q15349) Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1)| (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (MAP kinase-activated protein kinase 1c) (MAPKAPK1C) Length = 733 Score = 103 bits (257), Expect = 5e-22 Identities = 56/130 (43%), Positives = 77/130 (59%), Gaps = 1/130 (0%) Frame = +1 Query: 145 SFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIR 324 SF GT EY+APE++ GHT + DWW+ G+L++EML G PF+GK R+ T A IL + Sbjct: 218 SFCGTIEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAKLG 277 Query: 325 FPASISVSLPARQLIYRLLHRDPANRMGS-YEGSNEIKQHPFFRGINWALVRGTAPPKLD 501 P +S A+ L+ L R+P NR+G+ +G EIK+HPFF I+W T K Sbjct: 278 MPQFLSGE--AQSLLRALFKRNPCNRLGAGIDGVEEIKRHPFFVTIDW----NTLYRKEI 331 Query: 502 APLFSKDVGK 531 P F VG+ Sbjct: 332 KPPFKPAVGR 341 Score = 59.3 bits (142), Expect = 1e-08 Identities = 39/119 (32%), Positives = 62/119 (52%), Gaps = 9/119 (7%) Frame = +1 Query: 118 FAEPMRASNSFVGTEEY----IAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRG--- 276 FA+ +RA N + T Y +APE++ G+ +A D W+LGILLY ML G+TPF Sbjct: 557 FAKQLRAGNGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLGILLYTMLAGFTPFANGPD 616 Query: 277 KTRQRTFANILHKDIRFPAS--ISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPF 447 T + A I S+S A+ ++ ++LH DP R+ + ++ +HP+ Sbjct: 617 DTPEEILARIGSGKYALSGGNWDSISDAAKDVVSKMLHVDPHQRLTAM----QVLKHPW 671
>GAD8_SCHPO (Q9P7J8) Serine/threonine-protein kinase gad8 (EC 2.7.11.1)| Length = 569 Score = 103 bits (257), Expect = 5e-22 Identities = 51/109 (46%), Positives = 68/109 (62%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKD 318 +N+F GT EY+APE++ G G+T VDWW LG+LLYEM+ G PF + + IL Sbjct: 385 TNTFCGTPEYLAPELLLGHGYTKVVDWWTLGVLLYEMITGLPPFYDENINEMYRKILQDP 444 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINW 465 +RFP +I A+ L+ LL R P R+GS G+ EIK HPFF I+W Sbjct: 445 LRFPDNIDEK--AKDLLSGLLTRAPEKRLGS-GGAQEIKNHPFFDDIDW 490
>CBK1_KLULA (P31034) Serine/threonine-protein kinase CBK1 (EC 2.7.11.1)| Length = 718 Score = 102 bits (255), Expect = 9e-22 Identities = 51/118 (43%), Positives = 72/118 (61%), Gaps = 2/118 (1%) Frame = +1 Query: 145 SFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILH--KD 318 S VGT +YIAPEI G+ DWW+LG ++YE L G+ PF +T Q T+ I++ + Sbjct: 529 STVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQT 588 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINWALVRGTAPP 492 ++FP I +S A LI RLL NR+G + G++EIK HPFF G++W +R P Sbjct: 589 LQFPDDIHISYEAEDLIRRLLTHS-ENRLGRHGGADEIKAHPFFSGVDWNTIRQVEAP 645
>PKN3_MOUSE (Q8K045) Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein| kinase PKN-beta) (Protein-kinase C-related kinase 3) Length = 878 Score = 102 bits (255), Expect = 9e-22 Identities = 54/121 (44%), Positives = 73/121 (60%), Gaps = 3/121 (2%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKD 318 +++F GT E++APE++T +T AVDWW LG+LLYEML G PF G T + F I+ D Sbjct: 705 TSTFCGTPEFLAPEVLTQEAYTRAVDWWGLGVLLYEMLVGECPFPGDTEEEVFECIVSAD 764 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMGSYE-GSNEIKQHPFFRGINW--ALVRGTAP 489 + P +SV +LI +LL + P R+G+ E + EIK PFFR NW L R P Sbjct: 765 VPCPHFLSVQ--GLELIQKLLQKSPEKRLGAGERDAEEIKVQPFFRTTNWQALLARTVQP 822 Query: 490 P 492 P Sbjct: 823 P 823
>KS6A6_HUMAN (Q9UK32) Ribosomal protein S6 kinase alpha-6 (EC 2.7.11.1)| (S6K-alpha 6) (90 kDa ribosomal protein S6 kinase 6) (p90-RSK 6) (Ribosomal S6 kinase 4) (RSK-4) (pp90RSK4) Length = 745 Score = 102 bits (254), Expect = 1e-21 Identities = 50/107 (46%), Positives = 68/107 (63%) Frame = +1 Query: 145 SFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIR 324 SF GT EY+APE++ GH+ + DWW+ G+L++EML G PF+GK R T IL + Sbjct: 232 SFCGTVEYMAPEVVNRRGHSQSADWWSYGVLMFEMLTGTLPFQGKDRNETMNMILKAKLG 291 Query: 325 FPASISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINW 465 P +S A+ L+ L R+PANR+GS EG EIK+H FF I+W Sbjct: 292 MPQFLSAE--AQSLLRMLFKRNPANRLGS-EGVEEIKRHLFFANIDW 335 Score = 55.1 bits (131), Expect = 2e-07 Identities = 36/105 (34%), Positives = 53/105 (50%), Gaps = 10/105 (9%) Frame = +1 Query: 118 FAEPMRASNSFV----GTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTR 285 FA+ +R N + T ++APE++ G+ +A D W+LG+L Y ML GYTPF Sbjct: 568 FAKQLRGENGLLLTPCYTANFVAPEVLMQQGYDAACDIWSLGVLFYTMLAGYTPFANGPN 627 Query: 286 QRTFANILHKDIRFPASIS------VSLPARQLIYRLLHRDPANR 402 T IL + S+S +S A+ L+ +LH DP R Sbjct: 628 D-TPEEILLRIGNGKFSLSGGNWDNISDGAKDLLSHMLHMDPHQR 671
>CBK1_DEBHA (Q6BLJ9) Serine/threonine-protein kinase CBK1 (EC 2.7.11.1)| Length = 716 Score = 102 bits (253), Expect = 1e-21 Identities = 52/127 (40%), Positives = 77/127 (60%), Gaps = 2/127 (1%) Frame = +1 Query: 145 SFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILH--KD 318 S VGT +YIAPEI G+ DWW+LG +++E L G+ PF +T T+ IL+ + Sbjct: 532 STVGTPDYIAPEIFVHQGYGQECDWWSLGAIMFECLIGWPPFCSETPHETYRKILNWQET 591 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINWALVRGTAPPKL 498 ++ P I +S + LI +LL + NR+G Y G++E+K HPFFRG++W +R K+ Sbjct: 592 LQIPDDIHLSPESEDLIRKLL-TNAENRLGRYNGADELKLHPFFRGVDWDTIR-----KV 645 Query: 499 DAPLFSK 519 DAP K Sbjct: 646 DAPFIPK 652
>CBK1_ASHGO (Q754N7) Serine/threonine-protein kinase CBK1 (EC 2.7.11.1)| Length = 719 Score = 101 bits (252), Expect = 2e-21 Identities = 54/119 (45%), Positives = 73/119 (61%), Gaps = 3/119 (2%) Frame = +1 Query: 145 SFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILH--KD 318 S VGT +YIAPEI G+ DWW+LG ++YE L G+ PF +T Q T+ I++ + Sbjct: 530 STVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQT 589 Query: 319 IRFPASISVSLPARQLIYRLL-HRDPANRMGSYEGSNEIKQHPFFRGINWALVRGTAPP 492 + FP I +S A LI RLL H D R+G + G+NEIK HPFFRG++W +R P Sbjct: 590 LVFPDDIHISYEAEDLIRRLLSHAD--ERLGRH-GANEIKNHPFFRGVDWETIRQVGAP 645
>SCK2_SCHPO (Q10364) Serine/threonine-protein kinase sck2 (EC 2.7.11.1)| Length = 646 Score = 101 bits (252), Expect = 2e-21 Identities = 48/110 (43%), Positives = 75/110 (68%), Gaps = 1/110 (0%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITG-AGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHK 315 + +F GT +Y+APE+I AG+ VD+W+LG+LLYEM G++PF Q+ + NI+ Sbjct: 424 TRTFCGTTDYLAPEVILDEAGYDMMVDFWSLGVLLYEMTCGWSPFYADNTQQLYKNIVFG 483 Query: 316 DIRFPASISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINW 465 +RFP + +S+ AR LI LL+R+P +R+G++ E+ +HPFF GI+W Sbjct: 484 KVRFPRGL-LSVEARDLIKLLLNRNPKHRLGAHGDVEEVMKHPFFDGIDW 532
>SGK3_HUMAN (Q96BR1) Serine/threonine-protein kinase Sgk3 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 3) (Serum/glucocorticoid-regulated kinase-like) Length = 496 Score = 101 bits (251), Expect = 3e-21 Identities = 53/129 (41%), Positives = 74/129 (57%), Gaps = 1/129 (0%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKD 318 + +F GT EY+APE+I + + VDWW LG +LYEMLYG PF + + NILHK Sbjct: 318 TTTFCGTPEYLAPEVIRKQPYDNTVDWWCLGAVLYEMLYGLPPFYCRDVAEMYDNILHKP 377 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINWA-LVRGTAPPK 495 + VSL A ++ LL +D NR+G+ E EI+ HPFF ++WA LV+ PP Sbjct: 378 LSLRP--GVSLTAWSILEELLEKDRQNRLGAKEDFLEIQNHPFFESLSWADLVQKKIPPP 435 Query: 496 LDAPLFSKD 522 + + D Sbjct: 436 FNPNVAGPD 444
>PKN3_HUMAN (Q6P5Z2) Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein| kinase PKN-beta) (Protein-kinase C-related kinase 3) Length = 889 Score = 101 bits (251), Expect = 3e-21 Identities = 53/121 (43%), Positives = 73/121 (60%), Gaps = 3/121 (2%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKD 318 +++F GT E++APE++T +T AVDWW LG+LLYEML G PF G T + F I++ D Sbjct: 716 TSTFCGTPEFLAPEVLTQEAYTRAVDWWGLGVLLYEMLVGECPFPGDTEEEVFDCIVNMD 775 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMGSYE-GSNEIKQHPFFRGINW--ALVRGTAP 489 +P +SV + I +LL + P R+G+ E + EIK PFFR NW L R P Sbjct: 776 APYPGFLSVQ--GLEFIQKLLQKCPEKRLGAGEQDAEEIKVQPFFRTTNWQALLARTIQP 833 Query: 490 P 492 P Sbjct: 834 P 834
>CBK1_CANGA (Q6FP74) Serine/threonine-protein kinase CBK1 (EC 2.7.11.1)| Length = 773 Score = 101 bits (251), Expect = 3e-21 Identities = 50/118 (42%), Positives = 71/118 (60%), Gaps = 2/118 (1%) Frame = +1 Query: 145 SFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILH--KD 318 S VGT +YIAPEI G+ DWW+LG ++YE L G+ PF +T Q T+ I++ + Sbjct: 584 STVGTPDYIAPEIFLYQGYGQDCDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQT 643 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINWALVRGTAPP 492 ++FP + +S A LI RLL R+G G++EIK HPFFRG++W +R P Sbjct: 644 LQFPEDVHISYEAEDLIRRLLTHS-NQRLGRQGGADEIKSHPFFRGVDWNTIRQVEAP 700
>KS6AA_XENLA (P10665) Ribosomal protein S6 kinase 2 alpha (EC 2.7.11.1)| (Ribosomal protein S6 kinase II alpha) (S6KII-alpha) (P90-RSK) (MAP kinase-activated protein kinase 1) (MAPK-activated protein kinase 1) (MAPKAP kinase 1) (MAPKAPK-1) Length = 733 Score = 101 bits (251), Expect = 3e-21 Identities = 52/119 (43%), Positives = 74/119 (62%), Gaps = 3/119 (2%) Frame = +1 Query: 145 SFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIR 324 SF GT EY+APE++ GH+ + DWW+ G+L++EML G PF+GK R+ T IL + Sbjct: 221 SFCGTVEYMAPEVVNRQGHSHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLG 280 Query: 325 FPASISVSLPARQLIYRLLHRDPANRMGS-YEGSNEIKQHPFFRGINWALV--RGTAPP 492 P +S A+ L+ L R+P NR+GS EG+ EIK+ PFF I+W + R +PP Sbjct: 281 MPQFLSNE--AQSLLRALFKRNPTNRLGSAMEGAEEIKRQPFFSTIDWNKLFRREMSPP 337 Score = 62.8 bits (151), Expect = 1e-09 Identities = 41/105 (39%), Positives = 56/105 (53%), Gaps = 9/105 (8%) Frame = +1 Query: 118 FAEPMRASNSFVGTEEY----IAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFR---G 276 FA+ +RA N + T Y +APE++ G+ D W+LGILLY ML GYTPF G Sbjct: 558 FAKQLRADNGLLMTPCYTANFVAPEVLKRQGYDEGCDIWSLGILLYTMLAGYTPFANGLG 617 Query: 277 KTRQRTFANILHK--DIRFPASISVSLPARQLIYRLLHRDPANRM 405 T + A I +R +VS A+ L+ R+LH DP R+ Sbjct: 618 DTPEEILARIGSGKFTLRGGNWNTVSAAAKDLVSRMLHVDPHKRL 662
>KS6A1_RAT (Q63531) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1)| (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 735 Score = 101 bits (251), Expect = 3e-21 Identities = 49/108 (45%), Positives = 70/108 (64%), Gaps = 1/108 (0%) Frame = +1 Query: 145 SFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIR 324 SF GT EY+APE++ GHT + DWW+ G+L++EML G PF+GK R+ T IL + Sbjct: 221 SFCGTVEYMAPEVVNRQGHTHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLG 280 Query: 325 FPASISVSLPARQLIYRLLHRDPANRMGS-YEGSNEIKQHPFFRGINW 465 P +S A+ L+ L R+PANR+GS +G+ EIK+H F+ I+W Sbjct: 281 MPQFLSTE--AQSLLRALFKRNPANRLGSGPDGAEEIKRHIFYSTIDW 326 Score = 60.8 bits (146), Expect = 4e-09 Identities = 39/119 (32%), Positives = 59/119 (49%), Gaps = 9/119 (7%) Frame = +1 Query: 118 FAEPMRASNSFVGTEEY----IAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFR---G 276 FA+ +RA N + T Y +APE++ G+ D W+LG+LLY ML GYTPF Sbjct: 560 FAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDEGCDIWSLGVLLYTMLAGYTPFANGPS 619 Query: 277 KTRQRTFANILHKDIRFPAS--ISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPF 447 T + I +VS A+ L+ ++LH DP R+ + ++ QHP+ Sbjct: 620 DTPEEILTRISSGKFTLSGGNWNTVSETAKDLVSKMLHVDPHQRL----TAKQVLQHPW 674
>KS6A3_MOUSE (P18654) Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1)| (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (MAP kinase-activated protein kinase 1b) (MAPKAPK1B) Length = 740 Score = 101 bits (251), Expect = 3e-21 Identities = 49/108 (45%), Positives = 69/108 (63%), Gaps = 1/108 (0%) Frame = +1 Query: 145 SFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIR 324 SF GT EY+APE++ GHT + DWW+ G+L++EML G PF+GK R+ T IL + Sbjct: 227 SFCGTVEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLG 286 Query: 325 FPASISVSLPARQLIYRLLHRDPANRMGS-YEGSNEIKQHPFFRGINW 465 P +S A+ L+ L R+PANR+G+ +G EIK+H FF I+W Sbjct: 287 MPQFLSPE--AQSLLRMLFKRNPANRLGAGPDGVEEIKRHSFFSTIDW 332 Score = 62.4 bits (150), Expect = 1e-09 Identities = 45/139 (32%), Positives = 69/139 (49%), Gaps = 9/139 (6%) Frame = +1 Query: 118 FAEPMRASNSFVGTEEY----IAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRG--- 276 FA+ +RA N + T Y +APE++ G+ +A D W+LG+LLY ML GYTPF Sbjct: 564 FAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLGVLLYTMLTGYTPFANGPD 623 Query: 277 KTRQRTFANILHKDIRFPASI--SVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFF 450 T + A I SVS A+ L+ ++LH DP R+ + + +HP+ Sbjct: 624 DTPEEILARIGSGKFSLSGGYWNSVSDTAKDLVSKMLHVDPHQRL----TAALVLRHPWI 679 Query: 451 RGINWALVRGTAPPKLDAP 507 ++W + + DAP Sbjct: 680 --VHWDQLPQYQLNRQDAP 696
>KS6A3_HUMAN (P51812) Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1)| (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protei Length = 740 Score = 101 bits (251), Expect = 3e-21 Identities = 49/108 (45%), Positives = 69/108 (63%), Gaps = 1/108 (0%) Frame = +1 Query: 145 SFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIR 324 SF GT EY+APE++ GHT + DWW+ G+L++EML G PF+GK R+ T IL + Sbjct: 227 SFCGTVEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLG 286 Query: 325 FPASISVSLPARQLIYRLLHRDPANRMGS-YEGSNEIKQHPFFRGINW 465 P +S A+ L+ L R+PANR+G+ +G EIK+H FF I+W Sbjct: 287 MPQFLSPE--AQSLLRMLFKRNPANRLGAGPDGVEEIKRHSFFSTIDW 332 Score = 62.4 bits (150), Expect = 1e-09 Identities = 45/139 (32%), Positives = 69/139 (49%), Gaps = 9/139 (6%) Frame = +1 Query: 118 FAEPMRASNSFVGTEEY----IAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRG--- 276 FA+ +RA N + T Y +APE++ G+ +A D W+LG+LLY ML GYTPF Sbjct: 564 FAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLGVLLYTMLTGYTPFANGPD 623 Query: 277 KTRQRTFANILHKDIRFPASI--SVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFF 450 T + A I SVS A+ L+ ++LH DP R+ + + +HP+ Sbjct: 624 DTPEEILARIGSGKFSLSGGYWNSVSDTAKDLVSKMLHVDPHQRL----TAALVLRHPWI 679 Query: 451 RGINWALVRGTAPPKLDAP 507 ++W + + DAP Sbjct: 680 --VHWDQLPQYQLNRQDAP 696
>KPK1_ARATH (P42818) Serine/threonine-protein kinase AtPK1/AtPK6 (EC 2.7.11.1)| Length = 465 Score = 100 bits (250), Expect = 3e-21 Identities = 54/113 (47%), Positives = 72/113 (63%), Gaps = 4/113 (3%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPF---RGKTRQRTFANIL 309 SNS GT EY+APEI+ G GH A DWW++GILLYEML G PF +GK +Q+ I+ Sbjct: 288 SNSMCGTTEYMAPEIVRGKGHDKAADWWSVGILLYEMLTGKPPFLGSKGKIQQK----IV 343 Query: 310 HKDIRFPASISVSLPARQLIYRLLHRDPANRMGS-YEGSNEIKQHPFFRGINW 465 I+ P +S A ++ LL ++P R+GS G+ EIKQH +F+GINW Sbjct: 344 KDKIKLPQFLSNE--AHAILKGLLQKEPERRLGSGLSGAEEIKQHKWFKGINW 394
>SGK2_HUMAN (Q9HBY8) Serine/threonine-protein kinase Sgk2 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 2) Length = 427 Score = 100 bits (249), Expect = 4e-21 Identities = 49/114 (42%), Positives = 69/114 (60%) Frame = +1 Query: 124 EPMRASNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFAN 303 EP +++F GT EY+APE++ + AVDWW LG +LYEML+G PF + + + N Sbjct: 246 EPEDTTSTFCGTPEYLAPEVLRKEPYDRAVDWWCLGAVLYEMLHGLPPFYSQDVSQMYEN 305 Query: 304 ILHKDIRFPASISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINW 465 ILH+ ++ P +V+ A L+ LLH+D R+GS EIK H FF INW Sbjct: 306 ILHQPLQIPGGRTVA--ACDLLQSLLHKDQRQRLGSKADFLEIKNHVFFSPINW 357
>KS6A4_MOUSE (Q9Z2B9) Ribosomal protein S6 kinase alpha-4 (EC 2.7.11.1) (Nuclear| mitogen-and stress-activated protein kinase 2) (90 kDa ribosomal protein S6 kinase 4) (RSK-like protein kinase) (RLSK) Length = 773 Score = 100 bits (249), Expect = 4e-21 Identities = 56/135 (41%), Positives = 83/135 (61%), Gaps = 4/135 (2%) Frame = +1 Query: 115 FFAEPMRASNSFVGTEEYIAPEIITG-AGHTSAVDWWALGILLYEMLYGYTPFRGKTRQR 291 F E + SF GT EY+APEII AGH AVDWW+LGILL+E+L G +PF + + Sbjct: 186 FLTEEKERTFSFCGTIEYMAPEIIRSKAGHGKAVDWWSLGILLFELLTGASPFTLEGERN 245 Query: 292 TFANILHKDIRF--PASISVSLPARQLIYRLLHRDPANRMGS-YEGSNEIKQHPFFRGIN 462 T A + + ++ P + + A+ L+ RLL +DP R+G+ +G+ E+K HPFF+G++ Sbjct: 246 TQAEVSRRILKCSPPFPLRIGPVAQDLLQRLLCKDPKKRLGAGPQGAQEVKSHPFFQGLD 305 Query: 463 WALVRGTAPPKLDAP 507 W + A K+ AP Sbjct: 306 WWAL---AARKIPAP 317 Score = 53.5 bits (127), Expect = 6e-07 Identities = 52/151 (34%), Positives = 74/151 (49%), Gaps = 9/151 (5%) Frame = +1 Query: 121 AEPMRASNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKT---RQR 291 AEPM+ T +Y APE++ G+ + D W+LG++LY ML G PF+G + Q Sbjct: 563 AEPMQTP---CFTLQYAAPELLAQQGYDESCDLWSLGVILYMMLSGQVPFQGASGQGGQS 619 Query: 292 TFANILHK--DIRF----PASISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFR 453 A I+ K + RF A VS A++L+ LL DPA R+ EG R Sbjct: 620 QAAEIMCKIREGRFSLDGEAWQGVSEEAKELVRGLLTVDPAKRL-KLEG---------LR 669 Query: 454 GINWALVRGTAPPKLDAPLFSKDVGKGMGDA 546 +W L G+A + PL + DV + G A Sbjct: 670 SSSW-LQDGSA--RSSPPLRTPDVLESSGPA 697
>SGK2_RAT (Q8R4U9) Serine/threonine-protein kinase Sgk2 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 2) (Fragment) Length = 302 Score = 100 bits (249), Expect = 4e-21 Identities = 49/114 (42%), Positives = 69/114 (60%) Frame = +1 Query: 124 EPMRASNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFAN 303 EP +++F GT EY+APE++ + AVDWW LG +LYEML+G PF + + N Sbjct: 169 EPEETTSTFCGTPEYLAPEVLRKEPYDRAVDWWCLGAVLYEMLHGLPPFFNTDVAQMYEN 228 Query: 304 ILHKDIRFPASISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINW 465 ILH+ ++ P +V+ A L+ LLH+D R+GS E +IK H FF INW Sbjct: 229 ILHQPLQIPGGRTVA--ACDLLQGLLHKDQRQRLGSKEDFLDIKNHMFFSPINW 280
>SGK2_MOUSE (Q9QZS5) Serine/threonine-protein kinase Sgk2 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 2) Length = 367 Score = 100 bits (249), Expect = 4e-21 Identities = 49/114 (42%), Positives = 69/114 (60%) Frame = +1 Query: 124 EPMRASNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFAN 303 EP +++F GT EY+APE++ + AVDWW LG +LYEML+G PF + + N Sbjct: 186 EPEETTSTFCGTPEYLAPEVLRKEPYDRAVDWWCLGAVLYEMLHGLPPFFNTDVAQMYEN 245 Query: 304 ILHKDIRFPASISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINW 465 ILH+ ++ P +V+ A L+ LLH+D R+GS E +IK H FF INW Sbjct: 246 ILHQPLQIPGGRTVA--ACDLLQGLLHKDQRQRLGSKEDFLDIKNHMFFSPINW 297
>MAST3_HUMAN (O60307) Microtubule-associated serine/threonine-protein kinase 3| (EC 2.7.11.1) Length = 1309 Score = 100 bits (248), Expect = 6e-21 Identities = 53/121 (43%), Positives = 78/121 (64%), Gaps = 4/121 (3%) Frame = +1 Query: 154 GTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFP- 330 GT EYIAPE+I G+ VDWWA+G++LYE L G PF G T + F ++ +I +P Sbjct: 542 GTPEYIAPEVIFRQGYGKPVDWWAMGVVLYEFLVGCVPFFGDTPEELFGQVVSDEIMWPE 601 Query: 331 ASISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINWA-LVRGTAP--PKLD 501 ++ A+ LI RLL + P +R+G+ G++E+KQHPFF ++WA L+R A P+L+ Sbjct: 602 GDEALPADAQDLITRLLRQSPLDRLGT-GGTHEVKQHPFFLALDWAGLLRHKAEFVPQLE 660 Query: 502 A 504 A Sbjct: 661 A 661
>KS6A1_HUMAN (Q15418) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1)| (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 735 Score = 100 bits (248), Expect = 6e-21 Identities = 48/108 (44%), Positives = 70/108 (64%), Gaps = 1/108 (0%) Frame = +1 Query: 145 SFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIR 324 SF GT EY+APE++ GH+ + DWW+ G+L++EML G PF+GK R+ T IL + Sbjct: 221 SFCGTVEYMAPEVVNRQGHSHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLG 280 Query: 325 FPASISVSLPARQLIYRLLHRDPANRMGS-YEGSNEIKQHPFFRGINW 465 P +S A+ L+ L R+PANR+GS +G+ EIK+H F+ I+W Sbjct: 281 MPQFLSTE--AQSLLRALFKRNPANRLGSGPDGAEEIKRHVFYSTIDW 326 Score = 60.5 bits (145), Expect = 5e-09 Identities = 43/120 (35%), Positives = 63/120 (52%), Gaps = 10/120 (8%) Frame = +1 Query: 118 FAEPMRASNSFVGTEEY----IAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTR 285 FA+ +RA N + T Y +APE++ G+ D W+LGILLY ML GYTPF Sbjct: 560 FAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDEGCDIWSLGILLYTMLAGYTPFANGPS 619 Query: 286 QRTFANILHK--DIRFPAS----ISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPF 447 T IL + +F S +VS A+ L+ ++LH DP R+ + ++ QHP+ Sbjct: 620 D-TPEEILTRIGSGKFTLSGGNWNTVSETAKDLVSKMLHVDPHQRL----TAKQVLQHPW 674
>KS6AB_XENLA (P10666) Ribosomal protein S6 kinase 2 beta (EC 2.7.11.1)| (Ribosomal protein S6 kinase II beta) (S6KII-beta) (P90-RSK) Length = 629 Score = 100 bits (248), Expect = 6e-21 Identities = 51/119 (42%), Positives = 73/119 (61%), Gaps = 3/119 (2%) Frame = +1 Query: 145 SFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIR 324 SF GT EY+APE++ GH+ DWW+ G+L++EML G PF+GK R+ T IL + Sbjct: 221 SFCGTVEYMAPEVVNRQGHSHGADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLG 280 Query: 325 FPASISVSLPARQLIYRLLHRDPANRMGS-YEGSNEIKQHPFFRGINWALV--RGTAPP 492 P +S A+ L+ L R+ NR+GS EG+ E+K+HPFF I+W + R +PP Sbjct: 281 MPQFLSNE--AQSLLRALFKRNATNRLGSGVEGAEELKRHPFFSTIDWNKLYRRELSPP 337 Score = 52.0 bits (123), Expect = 2e-06 Identities = 29/70 (41%), Positives = 39/70 (55%), Gaps = 7/70 (10%) Frame = +1 Query: 118 FAEPMRASNSFVGTEEY----IAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFR---G 276 F++ +RA N + T Y +APE++ G+ D W+LGILLY ML GYTPF G Sbjct: 558 FSKQLRAENGLLMTPCYTANFVAPEVLKRQGYDEGCDIWSLGILLYTMLAGYTPFANGPG 617 Query: 277 KTRQRTFANI 306 T + A I Sbjct: 618 DTPEEILARI 627
>PK2_DICDI (P28178) Protein kinase 2 (EC 2.7.11.1)| Length = 479 Score = 99.8 bits (247), Expect = 7e-21 Identities = 48/107 (44%), Positives = 69/107 (64%) Frame = +1 Query: 145 SFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIR 324 +F GT EY+APE++ G GH AVDWW+LG LLYEML G PF + + IL+ +++ Sbjct: 309 TFCGTPEYLAPEVLNGHGHGCAVDWWSLGTLLYEMLTGLPPFYSQNVSTMYQKILNGELK 368 Query: 325 FPASISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINW 465 P IS A+ L+ LL R+ R+G+ +G E+KQHP+F+ I+W Sbjct: 369 IPTYISPE--AKSLLEGLLTREVDKRLGT-KGGGEVKQHPWFKNIDW 412
>SCK1_SCHPO (P50530) Serine/threonine-protein kinase sck1 (EC 2.7.11.1)| Length = 696 Score = 99.4 bits (246), Expect = 1e-20 Identities = 46/113 (40%), Positives = 74/113 (65%), Gaps = 1/113 (0%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIIT-GAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHK 315 +N+F GT EY+APE++ G+T VD+W+LG+L++EM G++PF Q+ + NI Sbjct: 460 TNTFCGTTEYLAPEVLLEDKGYTKQVDFWSLGVLVFEMCCGWSPFYAPDVQQMYRNIAFG 519 Query: 316 DIRFPASISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINWALV 474 +RFP + +S R + LL+R+P +R+G+ + E+K+HPFF INW L+ Sbjct: 520 KVRFPKGV-LSSEGRSFVRGLLNRNPNHRLGAVADTTELKEHPFFADINWDLL 571
>KRAC_DICDI (P54644) RAC-family serine/threonine-protein kinase homolog (EC| 2.7.11.1) Length = 444 Score = 99.4 bits (246), Expect = 1e-20 Identities = 53/123 (43%), Positives = 71/123 (57%), Gaps = 1/123 (0%) Frame = +1 Query: 127 PMRASNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANI 306 P + +F GT EY+APE++ G G+ VDWW+ G LLYEML G PF + Q + I Sbjct: 272 PTDKTGTFCGTPEYLAPEVLQGNGYGKQVDWWSFGSLLYEMLTGLPPFYNQDVQEMYRKI 331 Query: 307 LHKDIRFPASISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINW-ALVRGT 483 + + + FP IS AR L+ +LL RDP R+ N IK+HPFFR I+W L + Sbjct: 332 MMEKLSFPHFISPD--ARSLLEQLLERDPEKRLAD---PNLIKRHPFFRSIDWEQLFQKN 386 Query: 484 APP 492 PP Sbjct: 387 IPP 389
>ST38L_HUMAN (Q9Y2H1) Serine/threonine-protein kinase 38-like (EC 2.7.11.1)| (NDR2 protein kinase) (Nuclear Dbf2-related kinase 2) Length = 464 Score = 99.0 bits (245), Expect = 1e-20 Identities = 48/113 (42%), Positives = 70/113 (61%), Gaps = 2/113 (1%) Frame = +1 Query: 145 SFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILH--KD 318 S VGT +YIAPE+ G+ DWW+LG+++YEML GY PF +T Q T+ +++ + Sbjct: 282 STVGTPDYIAPEVFMQTGYNKLCDWWSLGVIMYEMLIGYPPFCSETPQETYRKVMNWKET 341 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINWALVR 477 + FP + +S A+ LI R D NR+G+ G EIK HPFF G++W +R Sbjct: 342 LVFPPEVPISEKAKDLILRFC-IDSENRIGN-SGVEEIKGHPFFEGVDWEHIR 392
>MAST2_MOUSE (Q60592) Microtubule-associated serine/threonine-protein kinase 2| (EC 2.7.11.1) Length = 1734 Score = 99.0 bits (245), Expect = 1e-20 Identities = 47/105 (44%), Positives = 66/105 (62%), Gaps = 1/105 (0%) Frame = +1 Query: 154 GTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPA 333 GT EYIAPE+I G+ VDWWA+GI+LYE L G PF G T + F ++ +I +P Sbjct: 628 GTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEIVWPE 687 Query: 334 SISVSLP-ARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINW 465 P A+ L +LLH++P R+G+ + E+KQHPFF G++W Sbjct: 688 GDDALPPDAQDLTSKLLHQNPLERLGT-SSAYEVKQHPFFMGLDW 731
>KAPC_YEAST (P05986) cAMP-dependent protein kinase type 3 (EC 2.7.11.11) (PKA| 3) Length = 398 Score = 98.6 bits (244), Expect = 2e-20 Identities = 49/138 (35%), Positives = 80/138 (57%), Gaps = 3/138 (2%) Frame = +1 Query: 154 GTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPA 333 GT +YIAPE+++ + +VDWW+ G+L+YEML GYTPF +T+ NIL+ +++FP Sbjct: 245 GTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYNSNTMKTYENILNAELKFPP 304 Query: 334 SISVSLPARQLIYRLLHRDPANRMGSYE-GSNEIKQHPFFRGINW--ALVRGTAPPKLDA 504 A+ L+ +L+ RD + R+G+ + GS ++K HP+F + W L R P Sbjct: 305 FFHPD--AQDLLKKLITRDLSERLGNLQNGSEDVKNHPWFNEVIWEKLLARYIETP---- 358 Query: 505 PLFSKDVGKGMGDAAAAD 558 + + +G GD + D Sbjct: 359 --YEPPIQQGQGDTSQFD 374
>ST38L_MOUSE (Q7TSE6) Serine/threonine-protein kinase 38-like (EC 2.7.11.1)| (NDR2 protein kinase) (Nuclear Dbf2-related kinase 2) Length = 464 Score = 98.2 bits (243), Expect = 2e-20 Identities = 48/113 (42%), Positives = 69/113 (61%), Gaps = 2/113 (1%) Frame = +1 Query: 145 SFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANIL--HKD 318 S VGT +YIAPE+ G+ DWW+LG+++YEML G+ PF +T Q T+ ++ + Sbjct: 282 STVGTPDYIAPEVFMQTGYNKLCDWWSLGVIMYEMLIGFPPFCSETPQETYRKVMSWKET 341 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINWALVR 477 + FP + VS A+ LI R D NR+G+ G EIK HPFF G++W +R Sbjct: 342 LAFPPEVPVSEKAKDLILRFC-TDSENRIGN-GGVEEIKGHPFFEGVDWGHIR 392
>SGK3_MOUSE (Q9ERE3) Serine/threonine-protein kinase Sgk3 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 3) (Serum/glucocorticoid-regulated kinase-like) (Cytokine independent survival kinase) Length = 496 Score = 98.2 bits (243), Expect = 2e-20 Identities = 51/129 (39%), Positives = 73/129 (56%), Gaps = 1/129 (0%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKD 318 + +F GT EY+APE+I + + VDWW LG +LYEMLYG PF + + NILHK Sbjct: 318 TTTFCGTPEYLAPEVIRKQPYDNTVDWWCLGAVLYEMLYGLPPFYCRDVAEMYDNILHKP 377 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINWA-LVRGTAPPK 495 + VSL A ++ LL ++ NR+G+ E EI+ HPFF ++W LV+ PP Sbjct: 378 LNLRP--GVSLTAWSILEELLEKNRQNRLGAKEDFLEIQNHPFFESLSWTDLVQKKIPPP 435 Query: 496 LDAPLFSKD 522 + + D Sbjct: 436 FNPNVAGPD 444
>CBK1_YARLI (Q6CFS5) Serine/threonine-protein kinase CBK1 (EC 2.7.11.1)| Length = 588 Score = 98.2 bits (243), Expect = 2e-20 Identities = 52/125 (41%), Positives = 77/125 (61%), Gaps = 5/125 (4%) Frame = +1 Query: 145 SFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILH--KD 318 S VGT +YIAPEI G+ DWW+LG +++E L G+ PF + + T+ I++ + Sbjct: 415 STVGTPDYIAPEIFVHQGYGQECDWWSLGAIMFECLVGWPPFCSEQPRETYHKIINWRET 474 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINWALVRG-TAP-- 489 ++FP + +S + LI RLL NR+G G+NEIK HPFFRG++W+ +R AP Sbjct: 475 LQFPDDVHLSPESEDLIRRLL-TSSENRLGRIGGANEIKSHPFFRGVDWSSIREFNAPFV 533 Query: 490 PKLDA 504 PKL + Sbjct: 534 PKLSS 538
>KAPA_YEAST (P06244) cAMP-dependent protein kinase type 1 (EC 2.7.11.11) (PKA| 1) (CDC25-suppressing protein kinase) (PK-25) Length = 397 Score = 98.2 bits (243), Expect = 2e-20 Identities = 48/138 (34%), Positives = 81/138 (58%), Gaps = 3/138 (2%) Frame = +1 Query: 154 GTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPA 333 GT +YIAPE+++ + ++DWW+ GIL+YEML GYTPF +T+ IL+ ++RFP Sbjct: 244 GTPDYIAPEVVSTKPYNKSIDWWSFGILIYEMLAGYTPFYDSNTMKTYEKILNAELRFPP 303 Query: 334 SISVSLPARQLIYRLLHRDPANRMGSYE-GSNEIKQHPFFRGINW--ALVRGTAPPKLDA 504 + + + L+ RL+ RD + R+G+ + G+ ++K HP+F+ + W L R P Sbjct: 304 FFNEDV--KDLLSRLITRDLSQRLGNLQNGTEDVKNHPWFKEVVWEKLLSRNIETP---- 357 Query: 505 PLFSKDVGKGMGDAAAAD 558 + + +G GD + D Sbjct: 358 --YEPPIQQGQGDTSQFD 373
>KS6B2_HUMAN (Q9UBS0) Ribosomal protein S6 kinase beta-2 (EC 2.7.11.1) (S6K2)| (70 kDa ribosomal protein S6 kinase 2) (p70-S6KB) (p70 ribosomal S6 kinase beta) (p70 S6Kbeta) (p70 S6 kinase beta) (S6K-beta) (p70-beta) (S6 kinase-related kinase) (SRK) (Serin Length = 482 Score = 98.2 bits (243), Expect = 2e-20 Identities = 45/110 (40%), Positives = 72/110 (65%), Gaps = 1/110 (0%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKD 318 +++F GT EY+APEI+ +GH AVDWW+LG L+Y+ML G PF + R++T I+ Sbjct: 226 THTFCGTIEYMAPEILVRSGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGK 285 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMGSYEG-SNEIKQHPFFRGINW 465 + P ++ AR L+ + L R+P+ R+G G + ++++HPFFR +NW Sbjct: 286 LALPPYLTPD--ARDLVKKFLKRNPSQRIGGGPGDAADVQRHPFFRHMNW 333
>MAST2_HUMAN (Q6P0Q8) Microtubule-associated serine/threonine-protein kinase 2| (EC 2.7.11.1) Length = 1798 Score = 98.2 bits (243), Expect = 2e-20 Identities = 47/105 (44%), Positives = 66/105 (62%), Gaps = 1/105 (0%) Frame = +1 Query: 154 GTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPA 333 GT EYIAPE+I G+ VDWWA+GI+LYE L G PF G T + F ++ +I +P Sbjct: 687 GTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEIVWPE 746 Query: 334 SISVSLP-ARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINW 465 P A+ L +LLH++P R+G+ + E+KQHPFF G++W Sbjct: 747 GDEALPPDAQDLTSKLLHQNPLERLGT-GSAYEVKQHPFFTGLDW 790
>SCH9_YEAST (P11792) Serine/threonine-protein kinase SCH9 (EC 2.7.11.1)| Length = 823 Score = 97.4 bits (241), Expect = 4e-20 Identities = 47/129 (36%), Positives = 79/129 (61%), Gaps = 2/129 (1%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITG-AGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHK 315 +N+F GT EY+APE++ G+T VD+W+LG+L++EM G++PF + Q+ + I Sbjct: 567 TNTFCGTTEYLAPELLLDETGYTKMVDFWSLGVLIFEMCCGWSPFFAENNQKMYQKIAFG 626 Query: 316 DIRFPASISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINW-ALVRGTAPP 492 ++FP + +S R + LL+R+P +R+G+ + E++ HPFF I+W AL + PP Sbjct: 627 KVKFPRDV-LSQEGRSFVKGLLNRNPKHRLGAIDDGRELRAHPFFADIDWEALKQKKIPP 685 Query: 493 KLDAPLFSK 519 L S+ Sbjct: 686 PFKPHLVSE 694
>KS6A4_HUMAN (O75676) Ribosomal protein S6 kinase alpha-4 (EC 2.7.11.1) (Nuclear| mitogen-and stress-activated protein kinase 2) (90 kDa ribosomal protein S6 kinase 4) (Ribosomal protein kinase B) (RSKB) Length = 772 Score = 97.1 bits (240), Expect = 5e-20 Identities = 54/135 (40%), Positives = 81/135 (60%), Gaps = 4/135 (2%) Frame = +1 Query: 115 FFAEPMRASNSFVGTEEYIAPEIITG-AGHTSAVDWWALGILLYEMLYGYTPFRGKTRQR 291 F E + SF GT EY+APEII GH AVDWW+LGILL+E+L G +PF + + Sbjct: 186 FLTEEKERTFSFCGTIEYMAPEIIRSKTGHGKAVDWWSLGILLFELLTGASPFTLEGERN 245 Query: 292 TFANILHKDIRF--PASISVSLPARQLIYRLLHRDPANRMGSY-EGSNEIKQHPFFRGIN 462 T A + + ++ P + A+ L+ RLL +DP R+G+ +G+ E++ HPFF+G++ Sbjct: 246 TQAEVSRRILKCSPPFPPRIGPVAQDLLQRLLCKDPKKRLGAGPQGAQEVRNHPFFQGLD 305 Query: 463 WALVRGTAPPKLDAP 507 W + A K+ AP Sbjct: 306 WVAL---AARKIPAP 317 Score = 54.7 bits (130), Expect = 3e-07 Identities = 49/139 (35%), Positives = 70/139 (50%), Gaps = 9/139 (6%) Frame = +1 Query: 157 TEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKT---RQRTFANILHK--DI 321 T +Y APE++ G+ + D W+LG++LY ML G PF+G + Q A I+ K + Sbjct: 572 TLQYAAPELLAQQGYDESCDLWSLGVILYMMLSGQVPFQGASGQGGQSQAAEIMCKIREG 631 Query: 322 RF----PASISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINWALVRGTAP 489 RF A VS A++L+ LL DPA R+ EG RG +W L G+A Sbjct: 632 RFSLDGEAWQGVSEEAKELVRGLLTVDPAKRL-KLEG---------LRGSSW-LQDGSA- 679 Query: 490 PKLDAPLFSKDVGKGMGDA 546 + PL + DV + G A Sbjct: 680 -RSSPPLRTPDVLESSGPA 697
>KS6B2_MOUSE (Q9Z1M4) Ribosomal protein S6 kinase beta-2 (EC 2.7.11.1) (S6K-beta| 2) (70 kDa ribosomal protein S6 kinase 2) (p70-S6KB) (p70 ribosomal S6 kinase beta) (p70 S6Kbeta) (S6K2) Length = 485 Score = 97.1 bits (240), Expect = 5e-20 Identities = 50/121 (41%), Positives = 73/121 (60%), Gaps = 3/121 (2%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKD 318 +++F GT EY+APEI+ GH AVDWW+LG L+Y+ML G PF + R++T I+ Sbjct: 226 THTFCGTIEYMAPEILVRTGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIKGK 285 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMGSYEG-SNEIKQHPFFRGINW--ALVRGTAP 489 + P ++ AR L + L R+P R+G G + ++++HPFFR INW L R P Sbjct: 286 LVLPPYLTPD--ARDLAKKFLKRNPTQRIGGGLGDAADVQRHPFFRHINWDDLLARRVDP 343 Query: 490 P 492 P Sbjct: 344 P 344
>KPK19_ARATH (Q39030) Serine/threonine-protein kinase AtPK19 (EC 2.7.11.1)| (Ribosomal-protein S6 kinase homolog) Length = 471 Score = 97.1 bits (240), Expect = 5e-20 Identities = 53/113 (46%), Positives = 71/113 (62%), Gaps = 4/113 (3%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPF---RGKTRQRTFANIL 309 SNS GT EY+APEI+ G GH A DWW++GILLYEML G PF +GK +Q+ I+ Sbjct: 294 SNSMCGTTEYMAPEIVRGKGHDKAADWWSVGILLYEMLTGKPPFLGSKGKIQQK----IV 349 Query: 310 HKDIRFPASISVSLPARQLIYRLLHRDPANRMGS-YEGSNEIKQHPFFRGINW 465 I+ P +S A L+ LL ++P R+GS G+ EIK+H +F+ INW Sbjct: 350 KDKIKLPQFLSNE--AHALLKGLLQKEPERRLGSGPSGAEEIKKHKWFKAINW 400
>CBK1_PNECA (Q6TGC6) Serine/threonine-protein kinase CBK1 (EC 2.7.11.1)| Length = 507 Score = 96.7 bits (239), Expect = 6e-20 Identities = 49/118 (41%), Positives = 71/118 (60%), Gaps = 2/118 (1%) Frame = +1 Query: 145 SFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILH--KD 318 S VGT +YIAPEI T G+ DWW+LG +++E L G+ PF + T+ I++ ++ Sbjct: 330 STVGTPDYIAPEIFTQHGYGQECDWWSLGAIMFECLIGWPPFCSENAHETYRKIINWREN 389 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINWALVRGTAPP 492 + FP + +S A LI +LL R+G Y G+N+IK HPFFRG+NW +R P Sbjct: 390 LYFPEDLHLSAEAEDLIRKLL-TSADQRLGRY-GANDIKLHPFFRGVNWDTIREINAP 445
>JIL1_DROME (Q9V3I5) Chromosomal serine/threonine-protein kinase JIL-1 (EC| 2.7.11.1) Length = 1207 Score = 96.7 bits (239), Expect = 6e-20 Identities = 55/129 (42%), Positives = 83/129 (64%), Gaps = 7/129 (5%) Frame = +1 Query: 112 IFFAEPMRASNSFVGTEEYIAPEII-TGA-GHTSAVDWWALGILLYEMLYGYTPFR---G 276 I AE ++SF GT EY+APEII TG GH SAVDWW++G+L +E+L G +PF G Sbjct: 413 ILTAENEYRAHSFCGTLEYMAPEIIRTGPPGHDSAVDWWSVGVLTFELLTGASPFATSDG 472 Query: 277 KTRQRTFANILHKD-IRFPASISVSLPARQLIYRLLHRDPANRM-GSYEGSNEIKQHPFF 450 + +Q + + K+ P+S S + AR + ++L ++P R+ G++ ++EIK+HPFF Sbjct: 473 QVQQSEISRRIQKEQPMIPSSFSAN--ARDFVLKMLEKNPKRRLGGNHRDASEIKEHPFF 530 Query: 451 RGINWALVR 477 GINW +R Sbjct: 531 NGINWQELR 539 Score = 38.1 bits (87), Expect = 0.026 Identities = 29/96 (30%), Positives = 42/96 (43%), Gaps = 14/96 (14%) Frame = +1 Query: 157 TEEYIAPEIITGAG---HTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRF 327 T +Y PE++ A ++ AVD + LG LY ML G+ P+R + H ++R Sbjct: 779 TLDYAPPEMLADANLVTYSPAVDIYGLGATLYTMLVGHRPYRQNEDDVDHSAAAHHELRK 838 Query: 328 PAS-----------ISVSLPARQLIYRLLHRDPANR 402 S S R L+ L RDPA+R Sbjct: 839 RMRRGTFNQRSMRWESASPAFRHLVSWCLQRDPADR 874
>KPCE_HUMAN (Q02156) Protein kinase C epsilon type (EC 2.7.11.13)| (nPKC-epsilon) Length = 737 Score = 96.3 bits (238), Expect = 8e-20 Identities = 46/115 (40%), Positives = 70/115 (60%), Gaps = 3/115 (2%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKD 318 + +F GT +YIAPEI+ + +VDWWALG+L+YEM+ G PF F +ILH D Sbjct: 564 TTTFCGTPDYIAPEILQELEYGPSVDWWALGVLMYEMMAGQPPFEADNEDDLFESILHDD 623 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMG---SYEGSNEIKQHPFFRGINWALV 474 + +P + +S A ++ + ++P R+G S G + IKQHPFF+ I+W L+ Sbjct: 624 VLYP--VWLSKEAVSILKAFMTKNPHKRLGCVASQNGEDAIKQHPFFKEIDWVLL 676
>KAPC_ASCSU (P49673) cAMP-dependent protein kinase catalytic subunit (EC| 2.7.11.11) (PKA C) Length = 337 Score = 95.5 bits (236), Expect = 1e-19 Identities = 52/141 (36%), Positives = 79/141 (56%), Gaps = 3/141 (2%) Frame = +1 Query: 115 FFAEPMRASNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRT 294 F E + + + GT EY+APE+I GH +AVDWW+LG+L+YEM+ G PFRGKT Sbjct: 173 FAKEVIDRTWTMCGTPEYLAPEVIGNKGHDTAVDWWSLGVLIYEMMIGIPPFRGKTLDEI 232 Query: 295 FANILHKDIRFPASISVSLPARQLIYRLLHRDPANRMGSY-EGSNEIKQHPFFRGINWAL 471 + I+ +RF S L A+ L+ +LL D R+G+ +G+ ++ H +F I+W Sbjct: 233 YEKIILGKLRFTRSF--DLFAKDLVKKLLQVDRTQRLGNQKDGAADVMNHKWFTDIDWDD 290 Query: 472 VRG--TAPPKLDAPLFSKDVG 528 V+ PP + + D G Sbjct: 291 VQNMKLTPPIIPTLYSNGDTG 311
>KPCE_RAT (P09216) Protein kinase C epsilon type (EC 2.7.11.13)| (nPKC-epsilon) Length = 737 Score = 95.1 bits (235), Expect = 2e-19 Identities = 45/115 (39%), Positives = 70/115 (60%), Gaps = 3/115 (2%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKD 318 + +F GT +YIAPEI+ + +VDWWALG+L+YEM+ G PF F +ILH D Sbjct: 564 TTTFCGTPDYIAPEILQELEYGPSVDWWALGVLMYEMMAGQPPFEADNEDDLFESILHDD 623 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMG---SYEGSNEIKQHPFFRGINWALV 474 + +P + +S A ++ + ++P R+G + G + IKQHPFF+ I+W L+ Sbjct: 624 VLYP--VWLSKEAVSILKAFMTKNPHKRLGCVAAQNGEDAIKQHPFFKEIDWVLL 676
>KPCE_MOUSE (P16054) Protein kinase C epsilon type (EC 2.7.11.13)| (nPKC-epsilon) Length = 737 Score = 95.1 bits (235), Expect = 2e-19 Identities = 45/115 (39%), Positives = 70/115 (60%), Gaps = 3/115 (2%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKD 318 + +F GT +YIAPEI+ + +VDWWALG+L+YEM+ G PF F +ILH D Sbjct: 564 TTTFCGTPDYIAPEILQELEYGPSVDWWALGVLMYEMMAGQPPFEADNEDDLFESILHDD 623 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMG---SYEGSNEIKQHPFFRGINWALV 474 + +P + +S A ++ + ++P R+G + G + IKQHPFF+ I+W L+ Sbjct: 624 VLYP--VWLSKEAVSILKAFMTKNPHKRLGCVAAQNGEDAIKQHPFFKEIDWVLL 676
>KAPB_SCHPO (P40376) cAMP-dependent protein kinase catalytic subunit (EC| 2.7.11.11) Length = 512 Score = 95.1 bits (235), Expect = 2e-19 Identities = 56/155 (36%), Positives = 88/155 (56%), Gaps = 3/155 (1%) Frame = +1 Query: 118 FAEPMRASN--SFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQR 291 FA+ + SN + GT +Y+APEII+ + A DWW+LGIL++EML GY PF + + Sbjct: 345 FAKRVSTSNCCTLCGTPDYLAPEIISLKPYNKAADWWSLGILIFEMLAGYPPFYSENPMK 404 Query: 292 TFANILHKDIRFPASISVSLPARQLIYRLLHRDPANRMGSY-EGSNEIKQHPFFRGINWA 468 + NIL + +P+ S + + L+ LL RD R G+ +GS +I HP+FR I+W Sbjct: 405 LYENILEGKVNYPSYFSPA--SIDLLSHLLQRDITCRYGNLKDGSMDIIMHPWFRDISWD 462 Query: 469 LVRGTAPPKLDAPLFSKDVGKGMGDAAAADNGTDM 573 + K++ P + + GMGD++ D D+ Sbjct: 463 KI---LTRKIEVP-YVPPIQAGMGDSSQFDAYADV 493
>KPC1_DROME (P05130) Protein kinase C, brain isozyme (EC 2.7.11.13) (PKC)| (dPKC53E(BR)) Length = 679 Score = 95.1 bits (235), Expect = 2e-19 Identities = 57/156 (36%), Positives = 80/156 (51%), Gaps = 3/156 (1%) Frame = +1 Query: 133 RASNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILH 312 + + +F GT +YIAPEII + +VDWWA G+LLYEML G PF G+ + FA I Sbjct: 504 KTTKTFCGTPDYIAPEIILYQPYGKSVDWWAYGVLLYEMLVGQPPFDGEDEEELFAAITD 563 Query: 313 KDIRFPASISVSLPARQLIYRLLHRDPANRMG-SYEGSNEIKQHPFFRGINWALV--RGT 483 ++ +P S+S A++ L + P R+G G +++ HPFFR I+W + R Sbjct: 564 HNVSYPKSLSKE--AKEACKGFLTKQPNKRLGCGSSGEEDVRLHPFFRRIDWEKIENREV 621 Query: 484 APPKLDAPLFSKDVGKGMGDAAAADNGTDMF*TKKV 591 PP KDV D TD+ T KV Sbjct: 622 QPPFKPKIKHRKDVSN--FDKQFTSEKTDLTPTDKV 655
>KPC3_DROME (P13678) Protein kinase C (EC 2.7.11.13) (PKC) (dPKC98F)| Length = 634 Score = 95.1 bits (235), Expect = 2e-19 Identities = 45/120 (37%), Positives = 71/120 (59%), Gaps = 2/120 (1%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKD 318 + +F GT +YIAPEI+ + ++VDWWALG+L+YEM+ G PF F +I+H D Sbjct: 459 TTTFCGTPDYIAPEILKEQEYGASVDWWALGVLMYEMMAGQPPFEADNEDELFDSIMHDD 518 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINWALV--RGTAPP 492 + +P + +S A ++ L ++P R+G NEI++HPFF ++W + R PP Sbjct: 519 VLYP--VWLSREAVSILKGFLTKNPEQRLGCTGDENEIRKHPFFAKLDWKELEKRNIKPP 576
>AKT3_MOUSE (Q9WUA6) RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-gamma) (Protein kinase Akt-3) (Protein kinase B, gamma) (PKB gamma) Length = 479 Score = 95.1 bits (235), Expect = 2e-19 Identities = 45/108 (41%), Positives = 69/108 (63%), Gaps = 1/108 (0%) Frame = +1 Query: 145 SFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIR 324 +F GT EY+APE++ + AVDWW LG+++YEM+ G PF + ++ F IL +DI+ Sbjct: 305 TFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIK 364 Query: 325 FPASISVSLPARQLIYRLLHRDPANRM-GSYEGSNEIKQHPFFRGINW 465 FP ++S A+ L+ LL +DP R+ G + + EI +H FF G+NW Sbjct: 365 FPRTLSSD--AKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNW 410
>AKT3_HUMAN (Q9Y243) RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-gamma) (Protein kinase Akt-3) (Protein kinase B, gamma) (PKB gamma) (STK-2) Length = 479 Score = 95.1 bits (235), Expect = 2e-19 Identities = 45/108 (41%), Positives = 69/108 (63%), Gaps = 1/108 (0%) Frame = +1 Query: 145 SFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIR 324 +F GT EY+APE++ + AVDWW LG+++YEM+ G PF + ++ F IL +DI+ Sbjct: 305 TFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIK 364 Query: 325 FPASISVSLPARQLIYRLLHRDPANRM-GSYEGSNEIKQHPFFRGINW 465 FP ++S A+ L+ LL +DP R+ G + + EI +H FF G+NW Sbjct: 365 FPRTLSSD--AKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNW 410
>KPCA_MOUSE (P20444) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 95.1 bits (235), Expect = 2e-19 Identities = 50/133 (37%), Positives = 75/133 (56%), Gaps = 1/133 (0%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKD 318 + +F GT +YIAPEII + +VDWWA G+LLYEML G PF G+ F +I+ + Sbjct: 494 TRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHN 553 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMG-SYEGSNEIKQHPFFRGINWALVRGTAPPK 495 + +P S+S A + L+ + PA R+G EG ++++H FFR I+W + + Sbjct: 554 VSYPKSLSKE--AVSICKGLMTKQPAKRLGCGPEGERDVREHAFFRRIDWEKLENR---E 608 Query: 496 LDAPLFSKDVGKG 534 + P K GKG Sbjct: 609 IQPPFKPKVCGKG 621
>KPCE_RABIT (P10830) Protein kinase C epsilon type (EC 2.7.11.13)| (nPKC-epsilon) Length = 736 Score = 95.1 bits (235), Expect = 2e-19 Identities = 45/115 (39%), Positives = 70/115 (60%), Gaps = 3/115 (2%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKD 318 + +F GT +YIAPEI+ + +VDWWALG+L+YEM+ G PF F +ILH D Sbjct: 563 TTTFCGTPDYIAPEILQELEYGPSVDWWALGVLMYEMMAGQPPFEADNEDDLFESILHDD 622 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMG---SYEGSNEIKQHPFFRGINWALV 474 + +P + +S A ++ + ++P R+G + G + IKQHPFF+ I+W L+ Sbjct: 623 VLYP--VWLSKEAVSILKAFMTKNPHKRLGCVAAQNGEDAIKQHPFFKEIDWVLL 675
>KPCD_HUMAN (Q05655) Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta)| Length = 676 Score = 94.7 bits (234), Expect = 2e-19 Identities = 48/120 (40%), Positives = 71/120 (59%), Gaps = 2/120 (1%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKD 318 +++F GT +YIAPEI+ G +T +VDWW+ G+LLYEML G +PF G F +I Sbjct: 505 ASTFCGTPDYIAPEILQGLKYTFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESIRVDT 564 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINWALV--RGTAPP 492 +P I+ ++ ++ +L R+P R+G + IK HPFF+ INW L+ R PP Sbjct: 565 PHYPRWITKE--SKDILEKLFEREPTKRLGM---TGNIKIHPFFKTINWTLLEKRRLEPP 619
>KPCA_RAT (P05696) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 94.7 bits (234), Expect = 2e-19 Identities = 50/133 (37%), Positives = 75/133 (56%), Gaps = 1/133 (0%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKD 318 + +F GT +YIAPEII + +VDWWA G+LLYEML G PF G+ F +I+ + Sbjct: 494 TRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHN 553 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMG-SYEGSNEIKQHPFFRGINWALVRGTAPPK 495 + +P S+S A + L+ + PA R+G EG ++++H FFR I+W + + Sbjct: 554 VSYPKSLSKE--AVSICKGLMTKHPAKRLGCGPEGERDVREHAFFRRIDWEKLENR---E 608 Query: 496 LDAPLFSKDVGKG 534 + P K GKG Sbjct: 609 IQPPFKPKVCGKG 621
>KPCA_RABIT (P10102) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 94.7 bits (234), Expect = 2e-19 Identities = 50/133 (37%), Positives = 75/133 (56%), Gaps = 1/133 (0%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKD 318 + +F GT +YIAPEII + +VDWWA G+LLYEML G PF G+ F +I+ + Sbjct: 494 TRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHN 553 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMG-SYEGSNEIKQHPFFRGINWALVRGTAPPK 495 + +P S+S A + L+ + PA R+G EG ++++H FFR I+W + + Sbjct: 554 VSYPKSLSKE--AVSICKGLMTKHPAKRLGCGPEGERDVREHAFFRRIDWEKLENR---E 608 Query: 496 LDAPLFSKDVGKG 534 + P K GKG Sbjct: 609 IQPPFKPKVCGKG 621
>KPCA_HUMAN (P17252) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 94.7 bits (234), Expect = 2e-19 Identities = 50/133 (37%), Positives = 75/133 (56%), Gaps = 1/133 (0%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKD 318 + +F GT +YIAPEII + +VDWWA G+LLYEML G PF G+ F +I+ + Sbjct: 494 TRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHN 553 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMG-SYEGSNEIKQHPFFRGINWALVRGTAPPK 495 + +P S+S A + L+ + PA R+G EG ++++H FFR I+W + + Sbjct: 554 VSYPKSLSKE--AVSICKGLMTKHPAKRLGCGPEGERDVREHAFFRRIDWEKLENR---E 608 Query: 496 LDAPLFSKDVGKG 534 + P K GKG Sbjct: 609 IQPPFKPKVCGKG 621
>AKT1_HUMAN (P31749) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (Protein kinase B) (PKB) (C-AKT) Length = 480 Score = 94.4 bits (233), Expect = 3e-19 Identities = 49/119 (41%), Positives = 72/119 (60%), Gaps = 3/119 (2%) Frame = +1 Query: 145 SFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIR 324 +F GT EY+APE++ + AVDWW LG+++YEM+ G PF + ++ F IL ++IR Sbjct: 308 TFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIR 367 Query: 325 FPASISVSLPARQLIYRLLHRDPANRM-GSYEGSNEIKQHPFFRGINWALV--RGTAPP 492 FP ++ A+ L+ LL +DP R+ G E + EI QH FF GI W V + +PP Sbjct: 368 FPRTLGPE--AKSLLSGLLKKDPKQRLGGGSEDAKEIMQHRFFAGIVWQHVYEKKLSPP 424
>KPCD_RAT (P09215) Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta)| Length = 673 Score = 94.4 bits (233), Expect = 3e-19 Identities = 48/120 (40%), Positives = 72/120 (60%), Gaps = 2/120 (1%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKD 318 +++F GT +YIAPEI+ G ++ +VDWW+ G+LLYEML G +PF G F +I Sbjct: 503 ASTFCGTPDYIAPEILQGLKYSFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESIRVDT 562 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINWALV--RGTAPP 492 +P I+ ++ ++ +L RDPA R+G + I+ HPFF+ INW L+ R PP Sbjct: 563 PHYPRWITKE--SKDIMEKLFERDPAKRLGV---TGNIRLHPFFKTINWNLLEKRKVEPP 617
>KPCD_CANFA (Q5PU49) Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta)| Length = 674 Score = 94.4 bits (233), Expect = 3e-19 Identities = 48/122 (39%), Positives = 72/122 (59%), Gaps = 2/122 (1%) Frame = +1 Query: 133 RASNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILH 312 + +++F GT +YIAPEI+ G ++ +VDWW+ G+LLYEML G +PF G F +I Sbjct: 501 KQASTFCGTPDYIAPEILQGLKYSFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESIRV 560 Query: 313 KDIRFPASISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINWALV--RGTA 486 +P I+ ++ ++ +LL RD R+G + IK HPFF+ INW L+ R Sbjct: 561 DTPHYPRWITKE--SKDILEKLLERDTTKRLGV---TGNIKIHPFFKTINWTLLEKRAVE 615 Query: 487 PP 492 PP Sbjct: 616 PP 617
>AKT3_RAT (Q63484) RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-gamma) (Protein kinase Akt-3) (Protein kinase B, gamma) (PKB gamma) Length = 454 Score = 94.4 bits (233), Expect = 3e-19 Identities = 45/108 (41%), Positives = 68/108 (62%), Gaps = 1/108 (0%) Frame = +1 Query: 145 SFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIR 324 +F GT EY+APE++ + AVDWW LG+++YEM+ G PF + ++ F IL +DI+ Sbjct: 305 TFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIK 364 Query: 325 FPASISVSLPARQLIYRLLHRDPANRM-GSYEGSNEIKQHPFFRGINW 465 FP ++S A+ L+ LL +DP R+ G + EI +H FF G+NW Sbjct: 365 FPRTLSSD--AKSLLSGLLIKDPNKRLGGGPDDPKEIMRHSFFSGVNW 410
>ORB6_SCHPO (O13310) Serine/threonine-protein kinase orb6 (EC 2.7.11.1)| Length = 469 Score = 94.0 bits (232), Expect = 4e-19 Identities = 50/118 (42%), Positives = 72/118 (61%), Gaps = 2/118 (1%) Frame = +1 Query: 145 SFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILH--KD 318 S VGT +YIAPEI G+ DWW+LG +++E L G+ PF + T+ I++ + Sbjct: 291 STVGTPDYIAPEIFLQQGYGQDCDWWSLGAIMFECLIGWPPFCSENSHETYRKIINWRET 350 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINWALVRGTAPP 492 + FP I +S+ AR L+ RL+ D +R+G G+ EI QHPFF GI+W +R TA P Sbjct: 351 LTFPNDIHLSIEARDLMDRLM-TDSEHRLGR-GGAIEIMQHPFFTGIDWDHIRETAAP 406
>KS6A5_CHICK (Q5F3L1) Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1)| Length = 789 Score = 94.0 bits (232), Expect = 4e-19 Identities = 49/122 (40%), Positives = 74/122 (60%), Gaps = 5/122 (4%) Frame = +1 Query: 115 FFAEPMRASNSFVGTEEYIAPEIITGA--GHTSAVDWWALGILLYEMLYGYTPFRGKTRQ 288 F + + SF GT EY+AP+I+ G GH AVDWW++G+L+YE+L G +PF + Sbjct: 192 FLTDENERAYSFCGTIEYMAPDIVRGGDTGHDKAVDWWSVGVLMYELLTGASPFTVDGEK 251 Query: 289 RTFANILHKDIRF--PASISVSLPARQLIYRLLHRDPANRMG-SYEGSNEIKQHPFFRGI 459 + A I + ++ P +S ++ +I RLL +DP R+G ++EIKQHPFF+ I Sbjct: 252 NSQAEISRRILKSEPPYPQEMSALSKDIIQRLLMKDPKKRLGCGPTDADEIKQHPFFQNI 311 Query: 460 NW 465 NW Sbjct: 312 NW 313 Score = 48.5 bits (114), Expect = 2e-05 Identities = 32/92 (34%), Positives = 47/92 (51%), Gaps = 9/92 (9%) Frame = +1 Query: 157 TEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILH--KDIR-- 324 T Y APE+ G+ + D W+LG++LY ML G PF+ + + T + L K I+ Sbjct: 575 TLHYAAPELFNHNGYDESCDLWSLGVILYTMLSGQVPFQSQDKSLTCTSALEIMKKIKKG 634 Query: 325 -----FPASISVSLPARQLIYRLLHRDPANRM 405 A +VS A++LI LL DP R+ Sbjct: 635 EFSFEGEAWKNVSEEAKELIQGLLTVDPNKRI 666
>SGK1_HUMAN (O00141) Serine/threonine-protein kinase Sgk1 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 1) Length = 431 Score = 93.6 bits (231), Expect = 5e-19 Identities = 46/109 (42%), Positives = 66/109 (60%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKD 318 +++F GT EY+APE++ + VDWW LG +LYEMLYG PF + + NIL+K Sbjct: 254 TSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKP 313 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINW 465 ++ +I+ S AR L+ LL +D R+G+ + EIK H FF INW Sbjct: 314 LQLKPNITNS--ARHLLEGLLQKDRTKRLGAKDDFMEIKSHVFFSLINW 360
>AKT2_HUMAN (P31751) RAC-beta serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta) Length = 481 Score = 93.6 bits (231), Expect = 5e-19 Identities = 45/108 (41%), Positives = 67/108 (62%), Gaps = 1/108 (0%) Frame = +1 Query: 145 SFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIR 324 +F GT EY+APE++ + AVDWW LG+++YEM+ G PF + +R F IL ++IR Sbjct: 309 TFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIR 368 Query: 325 FPASISVSLPARQLIYRLLHRDPANRM-GSYEGSNEIKQHPFFRGINW 465 FP ++S A+ L+ LL +DP R+ G + E+ +H FF INW Sbjct: 369 FPRTLSPE--AKSLLAGLLKKDPKQRLGGGPSDAKEVMEHRFFLSINW 414
>KAPC_DICDI (P34099) cAMP-dependent protein kinase catalytic subunit (EC| 2.7.11.11) Length = 648 Score = 93.6 bits (231), Expect = 5e-19 Identities = 50/105 (47%), Positives = 62/105 (59%), Gaps = 1/105 (0%) Frame = +1 Query: 154 GTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPA 333 GT EY+APEII GH AVDWWALGIL++EML GY PF + IL I FP Sbjct: 493 GTPEYLAPEIIQSKGHGKAVDWWALGILIFEMLAGYPPFYDDDTFAIYNKILAGRITFPL 552 Query: 334 SISVSLPARQLIYRLLHRDPANRMGSY-EGSNEIKQHPFFRGINW 465 V A+ LI RLL D R+G+ +G+ ++K H +F INW Sbjct: 553 GFDVD--AKDLIKRLLTADRTRRLGALKDGALDVKNHRWFSDINW 595
>KS6A5_HUMAN (O75582) Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1) (Nuclear| mitogen-and stress-activated protein kinase 1) (90 kDa ribosomal protein S6 kinase 5) (RSK-like protein kinase) (RSKL) Length = 802 Score = 93.6 bits (231), Expect = 5e-19 Identities = 51/122 (41%), Positives = 75/122 (61%), Gaps = 5/122 (4%) Frame = +1 Query: 115 FFAEPMRASNSFVGTEEYIAPEIITG--AGHTSAVDWWALGILLYEMLYGYTPFRGKTRQ 288 F A+ + SF GT EY+AP+I+ G +GH AVDWW+LG+L+YE+L G +PF + Sbjct: 202 FVADETERAYSFCGTIEYMAPDIVRGGDSGHDKAVDWWSLGVLMYELLTGASPFTVDGEK 261 Query: 289 RTFANILHKDIRF--PASISVSLPARQLIYRLLHRDPANRMG-SYEGSNEIKQHPFFRGI 459 + A I + ++ P +S A+ LI RLL +DP R+G ++EIK+H FF+ I Sbjct: 262 NSQAEISRRILKSEPPYPQEMSALAKDLIQRLLMKDPKKRLGCGPRDADEIKEHLFFQKI 321 Query: 460 NW 465 NW Sbjct: 322 NW 323 Score = 50.1 bits (118), Expect = 7e-06 Identities = 32/92 (34%), Positives = 43/92 (46%), Gaps = 9/92 (9%) Frame = +1 Query: 157 TEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRT-------FANILHK 315 T Y APE++ G+ + D W+LG++LY ML G PF+ R T I Sbjct: 585 TLHYAAPELLNQNGYDESCDLWSLGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKG 644 Query: 316 DIRFPASI--SVSLPARQLIYRLLHRDPANRM 405 D F +VS A+ LI LL DP R+ Sbjct: 645 DFSFEGEAWKNVSQEAKDLIQGLLTVDPNKRL 676
>KPCT_HUMAN (Q04759) Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta)| Length = 706 Score = 93.6 bits (231), Expect = 5e-19 Identities = 45/109 (41%), Positives = 67/109 (61%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKD 318 +N+F GT +YIAPEI+ G + +VDWW+ G+LLYEML G +PF G+ + F +I + Sbjct: 536 TNTFCGTPDYIAPEILLGQKYNHSVDWWSFGVLLYEMLIGQSPFHGQDEEELFHSIRMDN 595 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINW 465 +P + A+ L+ +L R+P R+G +I+QHP FR INW Sbjct: 596 PFYPRWLEKE--AKDLLVKLFVREPEKRLGV---RGDIRQHPLFREINW 639
>AKT1_DROME (Q8INB9) RAC serine/threonine-protein kinase (EC 2.7.11.1)| (DRAC-PK) (Akt) (Dakt1) (Protein kinase B) (PKB) Length = 611 Score = 93.6 bits (231), Expect = 5e-19 Identities = 48/122 (39%), Positives = 71/122 (58%), Gaps = 2/122 (1%) Frame = +1 Query: 133 RASNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILH 312 R + +F GT EY+APE++ + AVDWW G+++YEM+ G PF + F IL Sbjct: 419 RTTKTFCGTPEYLAPEVLDDNDYGQAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLILV 478 Query: 313 KDIRFPASISVSLPARQLIYRLLHRDPANRM-GSYEGSNEIKQHPFFRGINWA-LVRGTA 486 ++++FP +I+ A+ L+ LL +DP R+ G + EI+ HPFF INW LV Sbjct: 479 EEVKFPRNITDE--AKNLLAGLLAKDPKKRLGGGKDDVKEIQAHPFFASINWTDLVLKKI 536 Query: 487 PP 492 PP Sbjct: 537 PP 538
>KAPCA_SHEEP (Q9MZD9) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 93.2 bits (230), Expect = 7e-19 Identities = 54/137 (39%), Positives = 75/137 (54%), Gaps = 1/137 (0%) Frame = +1 Query: 154 GTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPA 333 GT EY+APEII G+ AVDWWALG+L+YEM GY PF + + I+ +RFP+ Sbjct: 200 GTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPS 259 Query: 334 SISVSLPARQLIYRLLHRDPANRMGSYE-GSNEIKQHPFFRGINWALVRGTAPPKLDAPL 510 S L + L+ LL D R G+ + G N+IK H +F +W + K++AP Sbjct: 260 HFSSDL--KDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAI---YQRKVEAPF 314 Query: 511 FSKDVGKGMGDAAAADN 561 K KG GD + D+ Sbjct: 315 IPK--FKGPGDTSNFDD 329
>KAPCA_RAT (P27791) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 93.2 bits (230), Expect = 7e-19 Identities = 54/137 (39%), Positives = 75/137 (54%), Gaps = 1/137 (0%) Frame = +1 Query: 154 GTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPA 333 GT EY+APEII G+ AVDWWALG+L+YEM GY PF + + I+ +RFP+ Sbjct: 200 GTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPS 259 Query: 334 SISVSLPARQLIYRLLHRDPANRMGSYE-GSNEIKQHPFFRGINWALVRGTAPPKLDAPL 510 S L + L+ LL D R G+ + G N+IK H +F +W + K++AP Sbjct: 260 HFSSDL--KDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAI---YQRKVEAPF 314 Query: 511 FSKDVGKGMGDAAAADN 561 K KG GD + D+ Sbjct: 315 IPK--FKGPGDTSNFDD 329
>KAPCA_PIG (P36887) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 93.2 bits (230), Expect = 7e-19 Identities = 54/137 (39%), Positives = 75/137 (54%), Gaps = 1/137 (0%) Frame = +1 Query: 154 GTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPA 333 GT EY+APEII G+ AVDWWALG+L+YEM GY PF + + I+ +RFP+ Sbjct: 200 GTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPS 259 Query: 334 SISVSLPARQLIYRLLHRDPANRMGSYE-GSNEIKQHPFFRGINWALVRGTAPPKLDAPL 510 S L + L+ LL D R G+ + G N+IK H +F +W + K++AP Sbjct: 260 HFSSDL--KDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAI---YQRKVEAPF 314 Query: 511 FSKDVGKGMGDAAAADN 561 K KG GD + D+ Sbjct: 315 IPK--FKGPGDTSNFDD 329
>KAPCA_MOUSE (P05132) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 93.2 bits (230), Expect = 7e-19 Identities = 54/137 (39%), Positives = 75/137 (54%), Gaps = 1/137 (0%) Frame = +1 Query: 154 GTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPA 333 GT EY+APEII G+ AVDWWALG+L+YEM GY PF + + I+ +RFP+ Sbjct: 200 GTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPS 259 Query: 334 SISVSLPARQLIYRLLHRDPANRMGSYE-GSNEIKQHPFFRGINWALVRGTAPPKLDAPL 510 S L + L+ LL D R G+ + G N+IK H +F +W + K++AP Sbjct: 260 HFSSDL--KDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAI---YQRKVEAPF 314 Query: 511 FSKDVGKGMGDAAAADN 561 K KG GD + D+ Sbjct: 315 IPK--FKGPGDTSNFDD 329
>KAPCA_HUMAN (P17612) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 93.2 bits (230), Expect = 7e-19 Identities = 54/137 (39%), Positives = 75/137 (54%), Gaps = 1/137 (0%) Frame = +1 Query: 154 GTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPA 333 GT EY+APEII G+ AVDWWALG+L+YEM GY PF + + I+ +RFP+ Sbjct: 200 GTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPS 259 Query: 334 SISVSLPARQLIYRLLHRDPANRMGSYE-GSNEIKQHPFFRGINWALVRGTAPPKLDAPL 510 S L + L+ LL D R G+ + G N+IK H +F +W + K++AP Sbjct: 260 HFSSDL--KDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAI---YQRKVEAPF 314 Query: 511 FSKDVGKGMGDAAAADN 561 K KG GD + D+ Sbjct: 315 IPK--FKGPGDTSNFDD 329
>KAPCA_CRIGR (P25321) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 93.2 bits (230), Expect = 7e-19 Identities = 54/137 (39%), Positives = 75/137 (54%), Gaps = 1/137 (0%) Frame = +1 Query: 154 GTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPA 333 GT EY+APEII G+ AVDWWALG+L+YEM GY PF + + I+ +RFP+ Sbjct: 200 GTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPS 259 Query: 334 SISVSLPARQLIYRLLHRDPANRMGSYE-GSNEIKQHPFFRGINWALVRGTAPPKLDAPL 510 S L + L+ LL D R G+ + G N+IK H +F +W + K++AP Sbjct: 260 HFSSDL--KDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAI---YQRKVEAPF 314 Query: 511 FSKDVGKGMGDAAAADN 561 K KG GD + D+ Sbjct: 315 IPK--FKGPGDTSNFDD 329
>KAPCA_BOVIN (P00517) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 93.2 bits (230), Expect = 7e-19 Identities = 54/137 (39%), Positives = 75/137 (54%), Gaps = 1/137 (0%) Frame = +1 Query: 154 GTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPA 333 GT EY+APEII G+ AVDWWALG+L+YEM GY PF + + I+ +RFP+ Sbjct: 200 GTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPS 259 Query: 334 SISVSLPARQLIYRLLHRDPANRMGSYE-GSNEIKQHPFFRGINWALVRGTAPPKLDAPL 510 S L + L+ LL D R G+ + G N+IK H +F +W + K++AP Sbjct: 260 HFSSDL--KDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAI---YQRKVEAPF 314 Query: 511 FSKDVGKGMGDAAAADN 561 K KG GD + D+ Sbjct: 315 IPK--FKGPGDTSNFDD 329
>KPCB_MOUSE (P68404) Protein kinase C beta type (EC 2.7.11.13) (PKC-beta)| (PKC-B) Length = 672 Score = 93.2 bits (230), Expect = 7e-19 Identities = 46/110 (41%), Positives = 66/110 (60%), Gaps = 1/110 (0%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKD 318 + +F GT +YIAPEII + +VDWWA G+LLYEML G PF G+ F +I+ + Sbjct: 497 TKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHN 556 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMG-SYEGSNEIKQHPFFRGINW 465 + +P S+S A + L+ + P R+G EG +IK+H FFR I+W Sbjct: 557 VAYPKSMSKEAVA--ICKGLMTKHPGKRLGCGPEGERDIKEHAFFRYIDW 604
>KPCB_BOVIN (P05126) Protein kinase C beta type (EC 2.7.11.13) (PKC-beta)| (PKC-B) Length = 672 Score = 93.2 bits (230), Expect = 7e-19 Identities = 46/110 (41%), Positives = 66/110 (60%), Gaps = 1/110 (0%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKD 318 + +F GT +YIAPEII + +VDWWA G+LLYEML G PF G+ F +I+ + Sbjct: 497 TKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHN 556 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMG-SYEGSNEIKQHPFFRGINW 465 + +P S+S A + L+ + P R+G EG +IK+H FFR I+W Sbjct: 557 VAYPKSMSKEAVA--ICKGLITKHPGKRLGCGPEGERDIKEHAFFRYIDW 604
>KPCB_RAT (P68403) Protein kinase C beta type (EC 2.7.11.13) (PKC-beta)| (PKC-B) Length = 670 Score = 93.2 bits (230), Expect = 7e-19 Identities = 46/110 (41%), Positives = 66/110 (60%), Gaps = 1/110 (0%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKD 318 + +F GT +YIAPEII + +VDWWA G+LLYEML G PF G+ F +I+ + Sbjct: 497 TKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHN 556 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMG-SYEGSNEIKQHPFFRGINW 465 + +P S+S A + L+ + P R+G EG +IK+H FFR I+W Sbjct: 557 VAYPKSMSKEAVA--ICKGLMTKHPGKRLGCGPEGERDIKEHAFFRYIDW 604
>KPCB_HUMAN (P05771) Protein kinase C beta type (EC 2.7.11.13) (PKC-beta)| (PKC-B) Length = 670 Score = 93.2 bits (230), Expect = 7e-19 Identities = 46/110 (41%), Positives = 66/110 (60%), Gaps = 1/110 (0%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKD 318 + +F GT +YIAPEII + +VDWWA G+LLYEML G PF G+ F +I+ + Sbjct: 497 TKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHN 556 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMG-SYEGSNEIKQHPFFRGINW 465 + +P S+S A + L+ + P R+G EG +IK+H FFR I+W Sbjct: 557 VAYPKSMSKEAVA--ICKGLMTKHPGKRLGCGPEGERDIKEHAFFRYIDW 604
>AKT2B_XENLA (Q6IP76) RAC-beta serine/threonine-protein kinase-B (EC 2.7.11.1)| (RAC-PK-beta-B) (Protein kinase Akt-2-B) (Protein kinase B, beta-B) (PKB beta-B) Length = 485 Score = 93.2 bits (230), Expect = 7e-19 Identities = 48/119 (40%), Positives = 71/119 (59%), Gaps = 3/119 (2%) Frame = +1 Query: 145 SFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIR 324 +F GT EY+APE++ + AVDWW LG+++YEM+ G PF + +R F IL ++ R Sbjct: 313 TFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEETR 372 Query: 325 FPASISVSLPARQLIYRLLHRDPANRM-GSYEGSNEIKQHPFFRGINWALV--RGTAPP 492 FP ++S A+ L+ LL +DP R+ G + + E+ H FF INW V R +PP Sbjct: 373 FPRTLSPE--AKSLLAGLLKKDPKQRLGGGPDDAQEVMSHGFFASINWQDVTERKLSPP 429
>PRKX_HUMAN (P51817) Serine/threonine-protein kinase PRKX (EC 2.7.11.1)| (Protein kinase PKX1) Length = 358 Score = 93.2 bits (230), Expect = 7e-19 Identities = 52/128 (40%), Positives = 72/128 (56%), Gaps = 1/128 (0%) Frame = +1 Query: 154 GTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPA 333 GT EY+APE+I GH AVDWWALGIL++EML G+ PF + IL I FP Sbjct: 206 GTPEYLAPEVIQSKGHGRAVDWWALGILIFEMLSGFPPFFDDNPFGIYQKILAGKIDFPR 265 Query: 334 SISVSLPARQLIYRLLHRDPANRMGSYE-GSNEIKQHPFFRGINWALVRGTAPPKLDAPL 510 + + + LI +LL D R+G+ + G+N++K H +FR ++W V KL P+ Sbjct: 266 HLDFHV--KDLIKKLLVVDRTRRLGNMKNGANDVKHHRWFRSVDWEAV---PQRKLKPPI 320 Query: 511 FSKDVGKG 534 K G G Sbjct: 321 VPKIAGDG 328
>SGK1_MOUSE (Q9WVC6) Serine/threonine-protein kinase Sgk1 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 1) Length = 431 Score = 93.2 bits (230), Expect = 7e-19 Identities = 46/109 (42%), Positives = 66/109 (60%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKD 318 +++F GT EY+APE++ + VDWW LG +LYEMLYG PF + + NIL+K Sbjct: 254 TSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKP 313 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINW 465 ++ +I+ S AR L+ LL +D R+G+ + EIK H FF INW Sbjct: 314 LQLKPNITNS--ARHLLEGLLQKDRTKRLGAKDDFMEIKSHIFFSLINW 360
>AKT1_BOVIN (Q01314) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (Protein kinase B) (PKB) Length = 480 Score = 93.2 bits (230), Expect = 7e-19 Identities = 46/108 (42%), Positives = 67/108 (62%), Gaps = 1/108 (0%) Frame = +1 Query: 145 SFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIR 324 +F GT EY+APE++ + AVDWW LG+++YEM+ G PF + ++ F IL ++IR Sbjct: 308 TFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIR 367 Query: 325 FPASISVSLPARQLIYRLLHRDPANRM-GSYEGSNEIKQHPFFRGINW 465 FP ++S A+ L+ LL +DP R+ G E + EI QH FF I W Sbjct: 368 FPRTLSPE--AKSLLSGLLKKDPKQRLGGGSEDAKEIMQHRFFASIVW 413
>KPCA_BOVIN (P04409) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 93.2 bits (230), Expect = 7e-19 Identities = 49/133 (36%), Positives = 74/133 (55%), Gaps = 1/133 (0%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKD 318 + +F GT +YIAPEII + +VDWWA G+LLYEML G PF G+ F +I+ + Sbjct: 494 TRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHN 553 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMG-SYEGSNEIKQHPFFRGINWALVRGTAPPK 495 + +P S+S A + L+ + P R+G EG ++++H FFR I+W + + Sbjct: 554 VSYPKSLSKE--AVSICKGLMTKHPGKRLGCGPEGERDVREHAFFRRIDWEKLENR---E 608 Query: 496 LDAPLFSKDVGKG 534 + P K GKG Sbjct: 609 IQPPFKPKVCGKG 621
>AKT2A_XENLA (Q7ZX15) RAC-beta serine/threonine-protein kinase-A (EC 2.7.11.1)| (RAC-PK-beta-A) (Protein kinase Akt-2-A) (Protein kinase B, beta-A) (PKB beta-A) Length = 486 Score = 93.2 bits (230), Expect = 7e-19 Identities = 49/119 (41%), Positives = 70/119 (58%), Gaps = 3/119 (2%) Frame = +1 Query: 145 SFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIR 324 +F GT EY+APE++ + AVDWW LG+++YEM+ G PF + +R F IL ++IR Sbjct: 314 TFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIR 373 Query: 325 FPASISVSLPARQLIYRLLHRDPANRM-GSYEGSNEIKQHPFFRGINWALV--RGTAPP 492 FP ++S A+ L+ LL +DP R+ G + E+ H FF INW V R PP Sbjct: 374 FPRTLSPE--AKSLLAGLLKKDPKQRLGGGPNDAQEVMSHRFFVSINWQDVTERKLTPP 430
>KAPCA_CANFA (Q8MJ44) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 349 Score = 93.2 bits (230), Expect = 7e-19 Identities = 54/137 (39%), Positives = 75/137 (54%), Gaps = 1/137 (0%) Frame = +1 Query: 154 GTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPA 333 GT EY+APEII G+ AVDWWALG+L+YEM GY PF + + I+ +RFP+ Sbjct: 199 GTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPS 258 Query: 334 SISVSLPARQLIYRLLHRDPANRMGSYE-GSNEIKQHPFFRGINWALVRGTAPPKLDAPL 510 S L + L+ LL D R G+ + G N+IK H +F +W + K++AP Sbjct: 259 HFSSDL--KDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAI---YQRKVEAPF 313 Query: 511 FSKDVGKGMGDAAAADN 561 K KG GD + D+ Sbjct: 314 IPK--FKGPGDTSNFDD 328
>MAST1_MOUSE (Q9R1L5) Microtubule-associated serine/threonine-protein kinase 1| (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase) Length = 1566 Score = 92.8 bits (229), Expect = 9e-19 Identities = 47/105 (44%), Positives = 65/105 (61%), Gaps = 1/105 (0%) Frame = +1 Query: 154 GTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFP- 330 GT EYIAPE+I G+ VDWWA+GI+LYE L G PF G T + F ++ DI +P Sbjct: 550 GTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDDILWPE 609 Query: 331 ASISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINW 465 ++ A+ LI LL +P R+G+ G+ E+KQH FFR ++W Sbjct: 610 GDEALPTDAQLLISSLLQTNPLVRLGA-GGAFEVKQHSFFRDLDW 653
>PRKX_MOUSE (Q922R0) Serine/threonine-protein kinase PRKX (EC 2.7.11.1)| (PKA-related protein kinase) Length = 355 Score = 92.8 bits (229), Expect = 9e-19 Identities = 53/128 (41%), Positives = 73/128 (57%), Gaps = 1/128 (0%) Frame = +1 Query: 154 GTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPA 333 GT EY+APE+I GH AVDWWALGIL++EML G+ PF + IL I FP Sbjct: 203 GTPEYLAPEVIQSKGHGRAVDWWALGILIFEMLSGFPPFFDDNPFGIYQKILACKIDFPR 262 Query: 334 SISVSLPARQLIYRLLHRDPANRMGSYE-GSNEIKQHPFFRGINWALVRGTAPPKLDAPL 510 + + ++ LI +LL D R+G+ + G+ +IK+H +FRG+ W V KL P+ Sbjct: 263 QLDFT--SKDLIKKLLVVDRTRRLGNMKNGAEDIKRHRWFRGVEWESV---PQRKLKPPI 317 Query: 511 FSKDVGKG 534 K G G Sbjct: 318 VPKLSGDG 325
>AKT1_XENLA (Q98TY9) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (Protein kinase Akt-1) (Protein kinase B, alpha) (PKB alpha) (xAkt) Length = 481 Score = 92.8 bits (229), Expect = 9e-19 Identities = 47/109 (43%), Positives = 69/109 (63%), Gaps = 2/109 (1%) Frame = +1 Query: 145 SFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIR 324 +F GT EY+APE++ + AVDWW LG+++YEM+ G PF + ++ F IL ++IR Sbjct: 309 TFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIR 368 Query: 325 FPASISVSLP-ARQLIYRLLHRDPANRM-GSYEGSNEIKQHPFFRGINW 465 FP ++ LP A+ L+ LL +DP R+ G + + EI QH FF GI W Sbjct: 369 FPRTL---LPEAKSLLSGLLKKDPKQRLGGGPDDAKEIMQHKFFAGIVW 414
>MAST1_RAT (Q810W7) Microtubule-associated serine/threonine-protein kinase 1| (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase) Length = 1570 Score = 92.8 bits (229), Expect = 9e-19 Identities = 47/105 (44%), Positives = 65/105 (61%), Gaps = 1/105 (0%) Frame = +1 Query: 154 GTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFP- 330 GT EYIAPE+I G+ VDWWA+GI+LYE L G PF G T + F ++ DI +P Sbjct: 551 GTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDDILWPE 610 Query: 331 ASISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINW 465 ++ A+ LI LL +P R+G+ G+ E+KQH FFR ++W Sbjct: 611 GDEALPTDAQLLISSLLQTNPLVRLGA-GGAFEVKQHSFFRDLDW 654
>MAST1_HUMAN (Q9Y2H9) Microtubule-associated serine/threonine-protein kinase 1| (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase) Length = 1570 Score = 92.8 bits (229), Expect = 9e-19 Identities = 47/105 (44%), Positives = 65/105 (61%), Gaps = 1/105 (0%) Frame = +1 Query: 154 GTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFP- 330 GT EYIAPE+I G+ VDWWA+GI+LYE L G PF G T + F ++ DI +P Sbjct: 549 GTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDDILWPE 608 Query: 331 ASISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINW 465 ++ A+ LI LL +P R+G+ G+ E+KQH FFR ++W Sbjct: 609 GDEALPTEAQLLISSLLQTNPLVRLGA-GGAFEVKQHSFFRDLDW 652
>KPCD_MOUSE (P28867) Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta)| Length = 674 Score = 92.8 bits (229), Expect = 9e-19 Identities = 47/120 (39%), Positives = 72/120 (60%), Gaps = 2/120 (1%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKD 318 +++F GT +YIAPEI+ G ++ +VDWW+ G+LLYEML G +PF G F +I Sbjct: 503 ASTFCGTPDYIAPEILQGLKYSFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESIRVDT 562 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINWALV--RGTAPP 492 +P I+ ++ ++ +L RDP R+G + I+ HPFF+ INW+L+ R PP Sbjct: 563 PHYPRWITKE--SKDIMEKLFERDPDKRLGV---TGNIRIHPFFKTINWSLLEKRKVEPP 617
>PCK2_SCHPO (P36583) Protein kinase C-like 2 (EC 2.7.11.13)| Length = 1016 Score = 92.8 bits (229), Expect = 9e-19 Identities = 50/131 (38%), Positives = 78/131 (59%), Gaps = 6/131 (4%) Frame = +1 Query: 145 SFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIR 324 +F GT E++APEI+ +T +VDWWA G+L+Y+ML G +PFRG+ + F IL + Sbjct: 842 TFCGTPEFMAPEILLEQQYTRSVDWWAFGVLIYQMLLGQSPFRGEDEEEIFDAILSDEPL 901 Query: 325 FPASISVSLPARQLIYRLLHRDPANRMGS-YEGSNEIKQHPFFRGINWALV--RGTAP-- 489 +P I + + ++ +LL RDP R+GS + ++ HPFF INW + + T P Sbjct: 902 YP--IHMPRDSVSILQQLLTRDPKKRLGSGPNDAEDVMTHPFFSNINWDDIYHKRTQPPY 959 Query: 490 -PKLDAPLFSK 519 P L++P +K Sbjct: 960 IPSLNSPTDTK 970
>KPCI_PONPY (Q5R4K9) Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota)| Length = 587 Score = 92.4 bits (228), Expect = 1e-18 Identities = 51/135 (37%), Positives = 76/135 (56%), Gaps = 13/135 (9%) Frame = +1 Query: 127 PMRASNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPF---------RGK 279 P +++F GT YIAPEI+ G + +VDWWALG+L++EM+ G +PF Sbjct: 397 PGDTTSTFCGTPNYIAPEILRGEDYGFSVDWWALGVLMFEMMAGRSPFDIVGSSDNPDQN 456 Query: 280 TRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDPANRMGSY--EGSNEIKQHPFFR 453 T F IL K IR P S+SV A ++ L++DP R+G + G +I+ HPFFR Sbjct: 457 TEDYLFQVILEKQIRIPRSLSVK--AASVLKSFLNKDPKERLGCHPQTGFADIQGHPFFR 514 Query: 454 GINWALV--RGTAPP 492 ++W ++ + PP Sbjct: 515 NVDWDMMEQKQVVPP 529
>KPCI_HUMAN (P41743) Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota)| (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota) (PRKC-lambda/iota) Length = 587 Score = 92.4 bits (228), Expect = 1e-18 Identities = 51/135 (37%), Positives = 76/135 (56%), Gaps = 13/135 (9%) Frame = +1 Query: 127 PMRASNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPF---------RGK 279 P +++F GT YIAPEI+ G + +VDWWALG+L++EM+ G +PF Sbjct: 397 PGDTTSTFCGTPNYIAPEILRGEDYGFSVDWWALGVLMFEMMAGRSPFDIVGSSDNPDQN 456 Query: 280 TRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDPANRMGSY--EGSNEIKQHPFFR 453 T F IL K IR P S+SV A ++ L++DP R+G + G +I+ HPFFR Sbjct: 457 TEDYLFQVILEKQIRIPRSLSVK--AASVLKSFLNKDPKERLGCHPQTGFADIQGHPFFR 514 Query: 454 GINWALV--RGTAPP 492 ++W ++ + PP Sbjct: 515 NVDWDMMEQKQVVPP 529
>KPCB_RABIT (P05772) Protein kinase C beta type (EC 2.7.11.13) (PKC-beta)| (PKC-B) Length = 670 Score = 92.4 bits (228), Expect = 1e-18 Identities = 46/110 (41%), Positives = 65/110 (59%), Gaps = 1/110 (0%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKD 318 + +F GT +YIAPEII + +VDWWA G+LLYEML G PF G+ F +I+ + Sbjct: 497 TKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHN 556 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMG-SYEGSNEIKQHPFFRGINW 465 + +P S+S A + L+ + P R+G EG +IK H FFR I+W Sbjct: 557 VAYPKSMSKEAVA--ICKGLMTKHPGKRLGCGPEGERDIKDHAFFRYIDW 604
>SGK1_RABIT (Q9XT18) Serine/threonine-protein kinase Sgk1 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 1) Length = 431 Score = 92.4 bits (228), Expect = 1e-18 Identities = 45/109 (41%), Positives = 66/109 (60%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKD 318 +++F GT EY+APE++ + VDWW LG +LYEMLYG PF + + NIL+K Sbjct: 254 TSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKP 313 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINW 465 ++ +I+ S AR L+ LL +D R+G+ + EI+ H FF INW Sbjct: 314 LQLKPNITNS--ARHLLEGLLQKDRTKRLGAKDDFMEIRNHVFFSLINW 360
>KPCI_MOUSE (Q62074) Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota)| (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota) Length = 586 Score = 92.4 bits (228), Expect = 1e-18 Identities = 51/135 (37%), Positives = 76/135 (56%), Gaps = 13/135 (9%) Frame = +1 Query: 127 PMRASNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPF---------RGK 279 P +++F GT YIAPEI+ G + +VDWWALG+L++EM+ G +PF Sbjct: 396 PGDTTSTFCGTPNYIAPEILRGEDYGFSVDWWALGVLMFEMMAGRSPFDIVGSSDNPDQN 455 Query: 280 TRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDPANRMGSY--EGSNEIKQHPFFR 453 T F IL K IR P S+SV A ++ L++DP R+G + G +I+ HPFFR Sbjct: 456 TEDYLFQVILEKQIRIPRSLSVK--AASVLKSFLNKDPKERLGCHPQTGFADIQGHPFFR 513 Query: 454 GINWALV--RGTAPP 492 ++W ++ + PP Sbjct: 514 NVDWDMMEQKQVVPP 528
>KPCT_MOUSE (Q02111) Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta)| Length = 707 Score = 92.0 bits (227), Expect = 2e-18 Identities = 44/109 (40%), Positives = 67/109 (61%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKD 318 +N+F GT +YIAPEI+ G + +VDWW+ G+L+YEML G +PF G+ + F +I + Sbjct: 536 TNTFCGTPDYIAPEILLGQKYNHSVDWWSFGVLVYEMLIGQSPFHGQDEEELFHSIRMDN 595 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINW 465 +P + A+ L+ +L R+P R+G +I+QHP FR INW Sbjct: 596 PFYPRWL--EREAKDLLVKLFVREPEKRLGV---RGDIRQHPLFREINW 639
>AKT_MLVAT (P31748) AKT kinase transforming protein (EC 2.7.11.1)| Length = 501 Score = 92.0 bits (227), Expect = 2e-18 Identities = 45/108 (41%), Positives = 66/108 (61%), Gaps = 1/108 (0%) Frame = +1 Query: 145 SFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIR 324 +F GT EY+APE++ + AVDWW LG+++YEM+ G PF + ++ F IL ++IR Sbjct: 329 TFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIR 388 Query: 325 FPASISVSLPARQLIYRLLHRDPANRM-GSYEGSNEIKQHPFFRGINW 465 FP ++ A+ L+ LL +DP R+ G E + EI QH FF I W Sbjct: 389 FPRTLGPE--AKSLLSGLLKKDPTQRLGGGSEDAKEIMQHRFFANIVW 434
>AKT2_RAT (P47197) RAC-beta serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta) Length = 481 Score = 92.0 bits (227), Expect = 2e-18 Identities = 44/108 (40%), Positives = 66/108 (61%), Gaps = 1/108 (0%) Frame = +1 Query: 145 SFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIR 324 +F GT EY+APE++ + AVDWW LG+++YEM+ G PF + +R F IL ++IR Sbjct: 309 TFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIR 368 Query: 325 FPASISVSLPARQLIYRLLHRDPANRM-GSYEGSNEIKQHPFFRGINW 465 FP ++ A+ L+ LL +DP R+ G + E+ +H FF INW Sbjct: 369 FPRTLGPE--AKSLLAGLLKKDPKQRLGGGPSDAKEVMEHRFFLSINW 414
>AKT2_MOUSE (Q60823) RAC-beta serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta) Length = 481 Score = 92.0 bits (227), Expect = 2e-18 Identities = 44/108 (40%), Positives = 66/108 (61%), Gaps = 1/108 (0%) Frame = +1 Query: 145 SFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIR 324 +F GT EY+APE++ + AVDWW LG+++YEM+ G PF + +R F IL ++IR Sbjct: 309 TFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIR 368 Query: 325 FPASISVSLPARQLIYRLLHRDPANRM-GSYEGSNEIKQHPFFRGINW 465 FP ++ A+ L+ LL +DP R+ G + E+ +H FF INW Sbjct: 369 FPRTLGPE--AKSLLAGLLKKDPKQRLGGGPSDAKEVMEHRFFLSINW 414
>AKT1_RAT (P47196) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (Protein kinase B) (PKB) Length = 480 Score = 92.0 bits (227), Expect = 2e-18 Identities = 45/108 (41%), Positives = 66/108 (61%), Gaps = 1/108 (0%) Frame = +1 Query: 145 SFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIR 324 +F GT EY+APE++ + AVDWW LG+++YEM+ G PF + ++ F IL ++IR Sbjct: 308 TFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIR 367 Query: 325 FPASISVSLPARQLIYRLLHRDPANRM-GSYEGSNEIKQHPFFRGINW 465 FP ++ A+ L+ LL +DP R+ G E + EI QH FF I W Sbjct: 368 FPRTLGPE--AKSLLSGLLKKDPTQRLGGGSEDAKEIMQHRFFANIVW 413
>KPCL_MOUSE (P23298) Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta)| (PKC-L) Length = 683 Score = 91.7 bits (226), Expect = 2e-18 Identities = 48/120 (40%), Positives = 72/120 (60%), Gaps = 4/120 (3%) Frame = +1 Query: 145 SFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIR 324 +F GT +YIAPEI+ + AVDWWA+G+LLYEML G+ PF + F IL+ ++ Sbjct: 513 TFCGTPDYIAPEILQEMLYGPAVDWWAMGVLLYEMLCGHAPFEAENEDDLFEAILNDEVV 572 Query: 325 FPASISVSLPARQLIYRLLHRDPANRMGSYE--GSNEIKQHPFFRGINWALV--RGTAPP 492 +P + AR ++ + ++P R+GS G +EI +HPFF+ I+WA + R PP Sbjct: 573 YPTWLHED--ARGILKSFMTKNPTMRLGSLTQGGEHEILRHPFFKEIDWAQLNHRQLEPP 630
>KS6A5_PONPY (Q5R4K3) Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1)| Length = 802 Score = 91.7 bits (226), Expect = 2e-18 Identities = 50/122 (40%), Positives = 74/122 (60%), Gaps = 5/122 (4%) Frame = +1 Query: 115 FFAEPMRASNSFVGTEEYIAPEIITG--AGHTSAVDWWALGILLYEMLYGYTPFRGKTRQ 288 F A+ + SF GT EY+AP+I+ G +GH AVDWW+LG+L+YE+L G +PF + Sbjct: 202 FVADETERAYSFCGTIEYMAPDIVRGGDSGHDKAVDWWSLGVLMYELLTGASPFTVDGEK 261 Query: 289 RTFANILHKDIRF--PASISVSLPARQLIYRLLHRDPANRMG-SYEGSNEIKQHPFFRGI 459 + A I + ++ P +S A+ LI LL +DP R+G ++EIK+H FF+ I Sbjct: 262 NSQAEISRRILKSEPPYPQEMSALAKDLIQHLLMKDPKKRLGCGPRDADEIKEHLFFQKI 321 Query: 460 NW 465 NW Sbjct: 322 NW 323 Score = 50.4 bits (119), Expect = 5e-06 Identities = 36/109 (33%), Positives = 48/109 (44%), Gaps = 13/109 (11%) Frame = +1 Query: 118 FAEPMRASNSFVGTE----EYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTR 285 FA P N + T Y APE++ G+ + D W+LG++LY ML G PF+ R Sbjct: 568 FARPKPPDNQPLKTPCFTLHYAAPELLNQNGYDESCDLWSLGVILYTMLSGQVPFQSHDR 627 Query: 286 QRT-------FANILHKDIRFPASI--SVSLPARQLIYRLLHRDPANRM 405 T I D F +VS A+ LI LL DP R+ Sbjct: 628 SLTCTSAVEIMKKIKKGDFSFEGEAWKNVSQEAKDLIQGLLTVDPNKRL 676
>PCK1_SCHPO (P36582) Protein kinase C-like 1 (EC 2.7.11.13)| Length = 988 Score = 91.7 bits (226), Expect = 2e-18 Identities = 46/110 (41%), Positives = 69/110 (62%), Gaps = 1/110 (0%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKD 318 +++F GT E++APEI+ ++ VDWWA G+L+Y+ML G +PF+G+ + F IL + Sbjct: 821 TSTFCGTPEFMAPEILLEQQYSKDVDWWAFGVLMYQMLLGQSPFKGEDEEEIFDAILSDE 880 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMGS-YEGSNEIKQHPFFRGINW 465 FP I++ A L+ LL RDP R+GS + +NE+ HPFF I W Sbjct: 881 PLFP--INMPADAVSLLRGLLTRDPNQRLGSGPKDANEVMAHPFFASIVW 928
>KPC4_DROME (P83099) Putative protein kinase C, delta type homolog (EC| 2.7.11.13) Length = 643 Score = 91.7 bits (226), Expect = 2e-18 Identities = 50/123 (40%), Positives = 72/123 (58%), Gaps = 3/123 (2%) Frame = +1 Query: 133 RASNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILH 312 + ++SF GT +Y+APEII G + VDWW+ G+LLYEML G +PF G F +I + Sbjct: 469 KTADSFCGTPDYMAPEIIKGEKYNQNVDWWSFGVLLYEMLIGQSPFSGCDEDELFWSICN 528 Query: 313 KDIRFPASISVSLPARQLIYRLLHRDPANRMGS-YEGSNEIKQHPFFRGINWALV--RGT 483 + FP + +S A ++ LL +D R+GS Y + +I H FFR I+W L+ R Sbjct: 529 EIPWFP--VYISAEATGILKGLLEKDYTKRIGSQYSPAGDIADHIFFRPIDWGLLEKRQI 586 Query: 484 APP 492 PP Sbjct: 587 EPP 589
>KPC2_CAEEL (P90980) Protein kinase C-like 2 (EC 2.7.11.13) (PKC2)| Length = 682 Score = 91.3 bits (225), Expect = 3e-18 Identities = 50/124 (40%), Positives = 70/124 (56%), Gaps = 6/124 (4%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKD 318 + +F GT +YIAPEII + +VDWWA G+LL+EML G PF G+ F I + Sbjct: 504 TKTFCGTPDYIAPEIILYQPYGKSVDWWAYGVLLFEMLAGQPPFDGEDEDELFTAITEHN 563 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMG----SYEGSNEIKQHPFFRGINWALV--RG 480 + +P S+S A L LL ++P+ R+G S +IK+HPFFR I+W + R Sbjct: 564 VSYPKSLSKE--AVSLCKALLIKNPSKRLGCTGDDESASRDIKEHPFFRRIDWFKIETRQ 621 Query: 481 TAPP 492 PP Sbjct: 622 IQPP 625
>KDC2_DROME (P16912) Protein kinase DC2 (EC 2.7.11.1)| Length = 583 Score = 91.3 bits (225), Expect = 3e-18 Identities = 49/118 (41%), Positives = 71/118 (60%), Gaps = 2/118 (1%) Frame = +1 Query: 118 FAEPMRASN-SFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRT 294 FA+ +R + GT EYIAPEII GH AVDWWALG+L+YEML GY PF + Sbjct: 418 FAKKLRDRTWTLCGTPEYIAPEIIQSKGHNKAVDWWALGVLIYEMLVGYPPFYDEQPFGI 477 Query: 295 FANILHKDIRFPASISVSLPARQLIYRLLHRDPANRMGSYE-GSNEIKQHPFFRGINW 465 + IL I + + A+ LI +LL D R+G+ + G++++K+H +F+ +NW Sbjct: 478 YEKILSGKIEWERHMDPI--AKDLIKKLLVNDRTKRLGNMKNGADDVKRHRWFKHLNW 533
>KPCZ_RAT (P09217) Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta)| Length = 592 Score = 91.3 bits (225), Expect = 3e-18 Identities = 53/133 (39%), Positives = 75/133 (56%), Gaps = 11/133 (8%) Frame = +1 Query: 127 PMRASNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPF-------RGKTR 285 P +++F GT YIAPEI+ G + +VDWWALG+L++EM+ G +PF T Sbjct: 404 PGDTTSTFCGTPNYIAPEILRGEEYGFSVDWWALGVLMFEMMAGRSPFDIITDNPDMNTE 463 Query: 286 QRTFANILHKDIRFPASISVSLPARQLIYRLLHRDPANRMG--SYEGSNEIKQHPFFRGI 459 F IL K IR P +SV A ++ L++DP R+G G ++IK H FFR I Sbjct: 464 DYLFQVILEKPIRIPRFLSVK--ASHVLKGFLNKDPKERLGCRPQTGFSDIKSHAFFRSI 521 Query: 460 NWALV--RGTAPP 492 +W L+ + T PP Sbjct: 522 DWDLLEKKQTLPP 534
>KPCZ_MOUSE (Q02956) Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta)| Length = 592 Score = 91.3 bits (225), Expect = 3e-18 Identities = 53/133 (39%), Positives = 75/133 (56%), Gaps = 11/133 (8%) Frame = +1 Query: 127 PMRASNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPF-------RGKTR 285 P +++F GT YIAPEI+ G + +VDWWALG+L++EM+ G +PF T Sbjct: 404 PGDTTSTFCGTPNYIAPEILRGEEYGFSVDWWALGVLMFEMMAGRSPFDIITDNPDMNTE 463 Query: 286 QRTFANILHKDIRFPASISVSLPARQLIYRLLHRDPANRMG--SYEGSNEIKQHPFFRGI 459 F IL K IR P +SV A ++ L++DP R+G G ++IK H FFR I Sbjct: 464 DYLFQVILEKPIRIPRFLSVK--ASHVLKGFLNKDPKERLGCRPQTGFSDIKSHAFFRSI 521 Query: 460 NWALV--RGTAPP 492 +W L+ + T PP Sbjct: 522 DWDLLEKKQTLPP 534
>SGK1_RAT (Q06226) Serine/threonine-protein kinase Sgk1 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 1) Length = 430 Score = 90.9 bits (224), Expect = 3e-18 Identities = 44/109 (40%), Positives = 65/109 (59%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKD 318 +++F GT EY+APE++ + VDWW LG +LYEMLYG PF + + NIL+K Sbjct: 254 TSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKP 313 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINW 465 ++ +++ AR L+ LL +D R+G+ + EIK H FF INW Sbjct: 314 LQLK---NITNSARHLLEGLLQKDRTKRLGAKDDFMEIKSHIFFSLINW 359
>KAPB_YEAST (P06245) cAMP-dependent protein kinase type 2 (EC 2.7.11.11) (PKA| 2) Length = 380 Score = 90.9 bits (224), Expect = 3e-18 Identities = 50/149 (33%), Positives = 80/149 (53%), Gaps = 1/149 (0%) Frame = +1 Query: 115 FFAEPMRASNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRT 294 F E + + GT +YIAPE+IT + +VDWW+LG+L+YEML GYTPF T +T Sbjct: 214 FAKEVQTVTWTLCGTPDYIAPEVITTKPYNKSVDWWSLGVLIYEMLAGYTPFYDTTPMKT 273 Query: 295 FANILHKDIRFPASISVSLPARQLIYRLLHRDPANRMGSYE-GSNEIKQHPFFRGINWAL 471 + IL + +P + L+ +L+ D R+G+ + GS +IK HP+F + W Sbjct: 274 YEKILQGKVVYPPYFHPDVV--DLLSKLITADLTRRIGNLQSGSRDIKAHPWFSEVVWER 331 Query: 472 VRGTAPPKLDAPLFSKDVGKGMGDAAAAD 558 + ++ P + + G+GD + D Sbjct: 332 L---LAKDIETP-YEPPITSGIGDTSLFD 356
>PDPK1_RAT (O55173) 3-phosphoinositide-dependent protein kinase 1 (EC| 2.7.11.1) (Protein kinase B kinase) (PkB kinase) Length = 559 Score = 90.9 bits (224), Expect = 3e-18 Identities = 58/173 (33%), Positives = 83/173 (47%), Gaps = 6/173 (3%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKD 318 +NSFVGT +Y++PE++T + D WALG ++Y+++ G PFR F I+ + Sbjct: 242 ANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLE 301 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMG--SYEGSNEIKQHPFFRGINWALVRGTAPP 492 FP AR L+ +LL D R+G EG +K HPFF I W + PP Sbjct: 302 YDFPEKFFPK--ARDLVEKLLVLDATKRLGCEEMEGYGPLKAHPFFESITWENLHQQTPP 359 Query: 493 KLDA--PLFSKDVGKGMGDAAAADNGTDMF*TKKVDGKTCQR--CSISAVLAQ 639 KL A P S+D G+ DN F +V + C++ A L Q Sbjct: 360 KLTAYLPAMSEDDEDCYGN---YDNLLSQFGCMQVSSSSSSHSLCAVDASLPQ 409
>KS6A_CAEEL (Q21734) Putative ribosomal protein S6 kinase alpha (EC 2.7.11.1)| Length = 784 Score = 90.9 bits (224), Expect = 3e-18 Identities = 57/158 (36%), Positives = 85/158 (53%), Gaps = 14/158 (8%) Frame = +1 Query: 145 SFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIR 324 SF GT EY+APE+I GH+ A D+W+LG+L++EML G+ PF+G+ R T IL + Sbjct: 263 SFCGTVEYMAPEVINRRGHSMAADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQILKAKLS 322 Query: 325 FPASISVSLPARQLIYRLLHRDPANRMGS-YEGSNEIKQHPFFRGINWA--LVRGTAPPK 495 P ++ A+ L+ L R+ NR+G+ +G EIK+H FF I++ L + PP Sbjct: 323 MPHFLTQE--AQSLLRALFKRNSQNRLGAGPDGVEEIKRHAFFAKIDFVKLLNKEIDPPF 380 Query: 496 LDA-----------PLFSKDVGKGMGDAAAADNGTDMF 576 A P F+K K A+ NG ++F Sbjct: 381 KPALSTVDSTSYFDPEFTKRTPKDSPALPASANGHEIF 418 Score = 50.1 bits (118), Expect = 7e-06 Identities = 42/148 (28%), Positives = 69/148 (46%), Gaps = 10/148 (6%) Frame = +1 Query: 118 FAEPMRASNSFVGTE----EYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTR 285 FA+ RA N + T +++APE++ G+ + D W+LG+LL+ ML G TPF Sbjct: 597 FAKQSRAENGMLMTPCYTAQFVAPEVLRKQGYDRSCDVWSLGVLLHTMLTGCTPF-AMGP 655 Query: 286 QRTFANILHK------DIRFPASISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPF 447 T IL + + P ++S A+ L+ ++L DP R+ + + QH Sbjct: 656 NDTPDQILQRVGDGKISMTHPVWDTISDEAKDLVRKMLDVDPNRRV----TAKQALQH-- 709 Query: 448 FRGINWALVRGTAPPKLDAPLFSKDVGK 531 W + P D P+ S+ VG+ Sbjct: 710 ----KWIGQKEALP---DRPIQSEQVGE 730
>KPC1_CAEEL (P34722) Protein kinase C-like 1 (EC 2.7.11.13) (PKC)| (Tetradecanoyl phorbol acetate resistant protein 1) Length = 704 Score = 90.9 bits (224), Expect = 3e-18 Identities = 53/142 (37%), Positives = 80/142 (56%), Gaps = 1/142 (0%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKD 318 +++F GT +YI+PEII G + AVD+W+ G+L+YEML G +PF G+ F +IL++ Sbjct: 532 ASTFCGTPDYISPEIIKGQLYNEAVDFWSFGVLMYEMLVGQSPFHGEGEDELFDSILNER 591 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMGSYE-GSNEIKQHPFFRGINWALVRGTAPPK 495 FP +IS A + + L R+P R+G E I+QH FFRG++W P Sbjct: 592 PYFPKTISKE--AAKCLSALFDRNPNTRLGMPECPDGPIRQHCFFRGVDWKRFENRQVP- 648 Query: 496 LDAPLFSKDVGKGMGDAAAADN 561 P F ++ K DA+ D+ Sbjct: 649 ---PPFKPNI-KSNSDASNFDD 666
>KAPCG_HUMAN (P22612) cAMP-dependent protein kinase, gamma-catalytic subunit (EC| 2.7.11.11) (PKA C-gamma) Length = 350 Score = 90.5 bits (223), Expect = 4e-18 Identities = 52/137 (37%), Positives = 74/137 (54%), Gaps = 1/137 (0%) Frame = +1 Query: 154 GTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPA 333 GT EY+APEII G+ AVDWWALG+L+YEM G+ PF + + I+ +RFP+ Sbjct: 200 GTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAVGFPPFYADQPIQIYEKIVSGRVRFPS 259 Query: 334 SISVSLPARQLIYRLLHRDPANRMGSY-EGSNEIKQHPFFRGINWALVRGTAPPKLDAPL 510 +S L + L+ LL D R G+ G +IK H +F +W + K++AP Sbjct: 260 KLSSDL--KHLLRSLLQVDLTKRFGNLRNGVGDIKNHKWFATTSWIAI---YEKKVEAPF 314 Query: 511 FSKDVGKGMGDAAAADN 561 K G GDA+ D+ Sbjct: 315 IPKYTGP--GDASNFDD 329
>KS6A5_MOUSE (Q8C050) Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1) (Nuclear| mitogen-and stress-activated protein kinase 1) (90 kDa ribosomal protein S6 kinase 5) (RSK-like protein kinase) (RLSK) Length = 863 Score = 90.1 bits (222), Expect = 6e-18 Identities = 49/122 (40%), Positives = 72/122 (59%), Gaps = 5/122 (4%) Frame = +1 Query: 115 FFAEPMRASNSFVGTEEYIAPEIITG--AGHTSAVDWWALGILLYEMLYGYTPFRGKTRQ 288 F A+ + SF GT EY+AP+I+ G +GH AVDWW+LG+L+YE+L G +PF + Sbjct: 201 FVADETERAYSFCGTIEYMAPDIVRGGDSGHDKAVDWWSLGVLMYELLTGASPFTVDGEK 260 Query: 289 RTFANILHKDIRF--PASISVSLPARQLIYRLLHRDPANRMG-SYEGSNEIKQHPFFRGI 459 + A I + ++ P +S A+ L+ RLL +DP R+G + EIK+H FF I Sbjct: 261 NSQAEISRRILKSEPPYPQEMSTVAKDLLQRLLMKDPKKRLGCGPRDAEEIKEHLFFEKI 320 Query: 460 NW 465 W Sbjct: 321 KW 322 Score = 52.0 bits (123), Expect = 2e-06 Identities = 33/92 (35%), Positives = 44/92 (47%), Gaps = 9/92 (9%) Frame = +1 Query: 157 TEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRT-------FANILHK 315 T Y APE++T G+ + D W+LG++LY ML G PF+ R T I Sbjct: 649 TLHYAAPELLTHNGYDESCDLWSLGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKG 708 Query: 316 DIRFPASI--SVSLPARQLIYRLLHRDPANRM 405 D F +VS A+ LI LL DP R+ Sbjct: 709 DFSFEGEAWKNVSQEAKDLIQGLLTVDPNKRL 740
>KAPB2_BOVIN (P24256) cAMP-dependent protein kinase, beta-2-catalytic subunit| (EC 2.7.11.11) (PKA C-beta-2) Length = 397 Score = 90.1 bits (222), Expect = 6e-18 Identities = 52/137 (37%), Positives = 75/137 (54%), Gaps = 1/137 (0%) Frame = +1 Query: 154 GTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPA 333 GT EY+APEII G+ AVDWWALG+L+YEM GY PF + + I+ +RFP+ Sbjct: 247 GTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPS 306 Query: 334 SISVSLPARQLIYRLLHRDPANRMGSYE-GSNEIKQHPFFRGINWALVRGTAPPKLDAPL 510 S L + L+ LL D R G+ + G ++IK H +F +W + K++AP Sbjct: 307 HFSSDL--KDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAI---YQRKVEAPF 361 Query: 511 FSKDVGKGMGDAAAADN 561 K +G GD + D+ Sbjct: 362 IPK--FRGSGDTSNFDD 376
>RIM15_YEAST (P43565) Serine/threonine-protein kinase RIM15 (EC 2.7.11.1)| Length = 1770 Score = 90.1 bits (222), Expect = 6e-18 Identities = 49/143 (34%), Positives = 79/143 (55%), Gaps = 11/143 (7%) Frame = +1 Query: 112 IFFAEPMRASNSFVGTEEYIAPEIITGAGHTSA-VDWWALGILLYEMLYGYTPFRGKTRQ 288 +F+ + + + F GT +Y+APE I G G + DWW++G + +E+L GY PF +T Sbjct: 1135 LFYPDDSKQNKKFFGTPDYLAPETIEGKGEDNKQCDWWSVGCIFFELLLGYPPFHAETPD 1194 Query: 289 RTFANILHKDIRFPASIS-------VSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPF 447 F IL I++P + ++ A+ LI +LL DPA R+G+ +G EIK HP+ Sbjct: 1195 AVFKKILSGVIQWPEFKNEEEEREFLTPEAKDLIEKLLVVDPAKRLGA-KGIQEIKDHPY 1253 Query: 448 FRGINWALV---RGTAPPKLDAP 507 F+ ++W V + P +D P Sbjct: 1254 FKNVDWDHVYDEEASFVPTIDNP 1276
>PDPK1_DROME (Q9W0V1) 3-phosphoinositide-dependent protein kinase 1 (EC| 2.7.11.1) (dPDK-1) (Serine/threonine-protein kinase 61C) (dSTPK61) Length = 836 Score = 90.1 bits (222), Expect = 6e-18 Identities = 46/121 (38%), Positives = 66/121 (54%), Gaps = 3/121 (2%) Frame = +1 Query: 145 SFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIR 324 SFVGT +Y++PE++ T A D WALG ++Y+M+ G PFRG F IL + Sbjct: 469 SFVGTAQYVSPEVLQNGPITPAADLWALGCIVYQMIAGLPPFRGSNDYVIFKEILDCAVD 528 Query: 325 FPASISVSLPARQLIYRLLHRDPANRMGSYEG---SNEIKQHPFFRGINWALVRGTAPPK 495 FP A L+ +LL DP +R+G+ + I+ HPFF GI+W +R PP Sbjct: 529 FPQGFDKD--AEDLVRKLLRVDPRDRLGAQDEFGYYESIRAHPFFAGIDWQTLRQQTPPP 586 Query: 496 L 498 + Sbjct: 587 I 587
>KAPCB_RAT (P68182) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 90.1 bits (222), Expect = 6e-18 Identities = 52/137 (37%), Positives = 75/137 (54%), Gaps = 1/137 (0%) Frame = +1 Query: 154 GTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPA 333 GT EY+APEII G+ AVDWWALG+L+YEM GY PF + + I+ +RFP+ Sbjct: 200 GTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPS 259 Query: 334 SISVSLPARQLIYRLLHRDPANRMGSYE-GSNEIKQHPFFRGINWALVRGTAPPKLDAPL 510 S L + L+ LL D R G+ + G ++IK H +F +W + K++AP Sbjct: 260 HFSSDL--KDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAI---YQRKVEAPF 314 Query: 511 FSKDVGKGMGDAAAADN 561 K +G GD + D+ Sbjct: 315 IPK--FRGSGDTSNFDD 329
>KAPCB_PIG (P05383) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 90.1 bits (222), Expect = 6e-18 Identities = 52/137 (37%), Positives = 75/137 (54%), Gaps = 1/137 (0%) Frame = +1 Query: 154 GTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPA 333 GT EY+APEII G+ AVDWWALG+L+YEM GY PF + + I+ +RFP+ Sbjct: 200 GTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPS 259 Query: 334 SISVSLPARQLIYRLLHRDPANRMGSYE-GSNEIKQHPFFRGINWALVRGTAPPKLDAPL 510 S L + L+ LL D R G+ + G ++IK H +F +W + K++AP Sbjct: 260 HFSSDL--KDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAI---YQRKVEAPF 314 Query: 511 FSKDVGKGMGDAAAADN 561 K +G GD + D+ Sbjct: 315 IPK--FRGSGDTSNFDD 329
>KAPCB_MOUSE (P68181) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 90.1 bits (222), Expect = 6e-18 Identities = 52/137 (37%), Positives = 75/137 (54%), Gaps = 1/137 (0%) Frame = +1 Query: 154 GTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPA 333 GT EY+APEII G+ AVDWWALG+L+YEM GY PF + + I+ +RFP+ Sbjct: 200 GTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPS 259 Query: 334 SISVSLPARQLIYRLLHRDPANRMGSYE-GSNEIKQHPFFRGINWALVRGTAPPKLDAPL 510 S L + L+ LL D R G+ + G ++IK H +F +W + K++AP Sbjct: 260 HFSSDL--KDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAI---YQRKVEAPF 314 Query: 511 FSKDVGKGMGDAAAADN 561 K +G GD + D+ Sbjct: 315 IPK--FRGSGDTSNFDD 329
>KAPCB_HUMAN (P22694) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 90.1 bits (222), Expect = 6e-18 Identities = 52/137 (37%), Positives = 75/137 (54%), Gaps = 1/137 (0%) Frame = +1 Query: 154 GTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPA 333 GT EY+APEII G+ AVDWWALG+L+YEM GY PF + + I+ +RFP+ Sbjct: 200 GTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPS 259 Query: 334 SISVSLPARQLIYRLLHRDPANRMGSYE-GSNEIKQHPFFRGINWALVRGTAPPKLDAPL 510 S L + L+ LL D R G+ + G ++IK H +F +W + K++AP Sbjct: 260 HFSSDL--KDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAI---YQRKVEAPF 314 Query: 511 FSKDVGKGMGDAAAADN 561 K +G GD + D+ Sbjct: 315 IPK--FRGSGDTSNFDD 329
>KAPCB_CRIGR (P68180) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 90.1 bits (222), Expect = 6e-18 Identities = 52/137 (37%), Positives = 75/137 (54%), Gaps = 1/137 (0%) Frame = +1 Query: 154 GTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPA 333 GT EY+APEII G+ AVDWWALG+L+YEM GY PF + + I+ +RFP+ Sbjct: 200 GTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPS 259 Query: 334 SISVSLPARQLIYRLLHRDPANRMGSYE-GSNEIKQHPFFRGINWALVRGTAPPKLDAPL 510 S L + L+ LL D R G+ + G ++IK H +F +W + K++AP Sbjct: 260 HFSSDL--KDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAI---YQRKVEAPF 314 Query: 511 FSKDVGKGMGDAAAADN 561 K +G GD + D+ Sbjct: 315 IPK--FRGSGDTSNFDD 329
>KAPB1_BOVIN (P05131) cAMP-dependent protein kinase, beta-1-catalytic subunit| (EC 2.7.11.11) (PKA C-beta-1) Length = 350 Score = 90.1 bits (222), Expect = 6e-18 Identities = 52/137 (37%), Positives = 75/137 (54%), Gaps = 1/137 (0%) Frame = +1 Query: 154 GTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPA 333 GT EY+APEII G+ AVDWWALG+L+YEM GY PF + + I+ +RFP+ Sbjct: 200 GTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPS 259 Query: 334 SISVSLPARQLIYRLLHRDPANRMGSYE-GSNEIKQHPFFRGINWALVRGTAPPKLDAPL 510 S L + L+ LL D R G+ + G ++IK H +F +W + K++AP Sbjct: 260 HFSSDL--KDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAI---YQRKVEAPF 314 Query: 511 FSKDVGKGMGDAAAADN 561 K +G GD + D+ Sbjct: 315 IPK--FRGSGDTSNFDD 329
>KGP1A_RABIT (O77676) cGMP-dependent protein kinase 1, alpha isozyme (EC| 2.7.11.12) (CGK 1 alpha) (cGKI-alpha) Length = 670 Score = 89.7 bits (221), Expect = 8e-18 Identities = 50/122 (40%), Positives = 73/122 (59%), Gaps = 4/122 (3%) Frame = +1 Query: 145 SFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILH--KD 318 +F GT EY+APEII GH + D+W+LGIL+YE+L G PF G +T+ IL Sbjct: 516 TFCGTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDM 575 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMGSYE-GSNEIKQHPFFRGINW-ALVRGTAPP 492 I FP I+ + A LI +L +P+ R+G+ + G +I++H +F G NW L +GT P Sbjct: 576 IEFPKKIAKN--AANLIKKLCRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTP 633 Query: 493 KL 498 + Sbjct: 634 PI 635
>KGP1A_HUMAN (Q13976) cGMP-dependent protein kinase 1, alpha isozyme (EC| 2.7.11.12) (CGK 1 alpha) (cGKI-alpha) Length = 670 Score = 89.7 bits (221), Expect = 8e-18 Identities = 50/122 (40%), Positives = 73/122 (59%), Gaps = 4/122 (3%) Frame = +1 Query: 145 SFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILH--KD 318 +F GT EY+APEII GH + D+W+LGIL+YE+L G PF G +T+ IL Sbjct: 516 TFCGTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDM 575 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMGSYE-GSNEIKQHPFFRGINW-ALVRGTAPP 492 I FP I+ + A LI +L +P+ R+G+ + G +I++H +F G NW L +GT P Sbjct: 576 IEFPKKIAKN--AANLIKKLCRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTP 633 Query: 493 KL 498 + Sbjct: 634 PI 635
>KGP1A_BOVIN (P00516) cGMP-dependent protein kinase 1, alpha isozyme (EC| 2.7.11.12) (CGK 1 alpha) (cGKI-alpha) Length = 670 Score = 89.7 bits (221), Expect = 8e-18 Identities = 50/122 (40%), Positives = 73/122 (59%), Gaps = 4/122 (3%) Frame = +1 Query: 145 SFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILH--KD 318 +F GT EY+APEII GH + D+W+LGIL+YE+L G PF G +T+ IL Sbjct: 516 TFCGTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDM 575 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMGSYE-GSNEIKQHPFFRGINW-ALVRGTAPP 492 I FP I+ + A LI +L +P+ R+G+ + G +I++H +F G NW L +GT P Sbjct: 576 IEFPKKIAKN--AANLIKKLCRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTP 633 Query: 493 KL 498 + Sbjct: 634 PI 635
>PDPK1_MOUSE (Q9Z2A0) 3-phosphoinositide-dependent protein kinase 1 (EC| 2.7.11.1) (mPDK1) Length = 559 Score = 89.7 bits (221), Expect = 8e-18 Identities = 49/132 (37%), Positives = 69/132 (52%), Gaps = 4/132 (3%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKD 318 +NSFVGT +Y++PE++T + D WALG ++Y+++ G PFR F I+ + Sbjct: 242 ANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLE 301 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMG--SYEGSNEIKQHPFFRGINWALVRGTAPP 492 FP AR L+ +LL D R+G EG +K HPFF I W + PP Sbjct: 302 YHFPEKFFPK--ARDLVEKLLVLDATKRLGCEEMEGYGPLKAHPFFETITWENLHQQTPP 359 Query: 493 KLDA--PLFSKD 522 KL A P S+D Sbjct: 360 KLTAYLPAMSED 371
>KPCZ_RABIT (O19111) Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta)| Length = 591 Score = 89.7 bits (221), Expect = 8e-18 Identities = 54/148 (36%), Positives = 76/148 (51%), Gaps = 9/148 (6%) Frame = +1 Query: 127 PMRASNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPF-------RGKTR 285 P +++F GT YIAPEI+ G + +VDWWALG+L++EM+ G +PF T Sbjct: 403 PGDTTSTFCGTPNYIAPEILRGEEYGFSVDWWALGVLMFEMMAGRSPFDIITDNPDMNTE 462 Query: 286 QRTFANILHKDIRFPASISVSLPARQLIYRLLHRDPANRMG--SYEGSNEIKQHPFFRGI 459 F IL K IR P +SV A ++ L++DP R+G G ++IK H FFR I Sbjct: 463 DYLFQVILEKPIRIPRFLSVK--ASHVLKGFLNKDPKERLGCRPQTGFSDIKSHAFFRSI 520 Query: 460 NWALVRGTAPPKLDAPLFSKDVGKGMGD 543 +W L+ P + D G D Sbjct: 521 DWDLLEKKQALPPFQPQITDDYGLDNSD 548
>AKT1_MOUSE (P31750) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (AKT1 kinase) (Protein kinase B) (PKB) (C-AKT) (Thymoma viral proto-oncogene) Length = 480 Score = 89.7 bits (221), Expect = 8e-18 Identities = 44/108 (40%), Positives = 65/108 (60%), Gaps = 1/108 (0%) Frame = +1 Query: 145 SFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIR 324 +F GT EY+APE++ + AVDWW LG+++YEM+ G PF + ++ F IL ++I Sbjct: 308 TFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIA 367 Query: 325 FPASISVSLPARQLIYRLLHRDPANRM-GSYEGSNEIKQHPFFRGINW 465 FP ++ A+ L+ LL +DP R+ G E + EI QH FF I W Sbjct: 368 FPRTLGPE--AKSLLSGLLKKDPTQRLGGGSEDAKEIMQHRFFANIVW 413
>STK38_HUMAN (Q15208) Serine/threonine-protein kinase 38 (EC 2.7.11.1) (NDR1| protein kinase) (Nuclear Dbf2-related kinase 1) Length = 465 Score = 89.7 bits (221), Expect = 8e-18 Identities = 44/113 (38%), Positives = 69/113 (61%), Gaps = 2/113 (1%) Frame = +1 Query: 145 SFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILH--KD 318 S VGT +YIAPE+ G+ DWW+LG+++YEML GY PF +T Q T+ +++ + Sbjct: 281 STVGTPDYIAPEVFMQTGYNKLCDWWSLGVIMYEMLIGYPPFCSETPQETYKKVMNWKET 340 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINWALVR 477 + FP + +S A+ LI R + +R+G+ G EIK + FF G++W +R Sbjct: 341 LTFPPEVPISEKAKDLILRFC-CEWEHRIGA-PGVEEIKSNSFFEGVDWEHIR 391
>MASTL_MOUSE (Q8C0P0) Microtubule-associated serine/threonine-protein kinase-like| (EC 2.7.11.1) Length = 865 Score = 89.7 bits (221), Expect = 8e-18 Identities = 47/120 (39%), Positives = 68/120 (56%), Gaps = 1/120 (0%) Frame = +1 Query: 151 VGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFP 330 +GT +Y+APE++ G H AVDWWALG+ L+E L G PF +T Q+ F NIL +DI +P Sbjct: 725 LGTPDYLAPELLLGTAHGPAVDWWALGVCLFEFLTGIPPFNDETPQQVFQNILKRDIPWP 784 Query: 331 -ASISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINWALVRGTAPPKLDAP 507 +S A+ + LL D + R G E+KQHP F ++W ++ P + P Sbjct: 785 EGEEKLSDNAQSAMDMLLTIDDSKR----AGMRELKQHPLFSEVDWENLQHQTMPFVPQP 840
>KGP1B_MOUSE (Q9Z0Z0) cGMP-dependent protein kinase 1, beta isozyme (EC| 2.7.11.12) (cGK 1 beta) (cGKI-beta) Length = 686 Score = 89.7 bits (221), Expect = 8e-18 Identities = 50/122 (40%), Positives = 73/122 (59%), Gaps = 4/122 (3%) Frame = +1 Query: 145 SFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILH--KD 318 +F GT EY+APEII GH + D+W+LGIL+YE+L G PF G +T+ IL Sbjct: 532 TFCGTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDM 591 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMGSYE-GSNEIKQHPFFRGINW-ALVRGTAPP 492 I FP I+ + A LI +L +P+ R+G+ + G +I++H +F G NW L +GT P Sbjct: 592 IEFPKKIAKN--AANLIKKLCRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTP 649 Query: 493 KL 498 + Sbjct: 650 PI 651
>KGP1B_HUMAN (P14619) cGMP-dependent protein kinase 1, beta isozyme (EC| 2.7.11.12) (cGK 1 beta) (cGKI-beta) Length = 686 Score = 89.7 bits (221), Expect = 8e-18 Identities = 50/122 (40%), Positives = 73/122 (59%), Gaps = 4/122 (3%) Frame = +1 Query: 145 SFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILH--KD 318 +F GT EY+APEII GH + D+W+LGIL+YE+L G PF G +T+ IL Sbjct: 532 TFCGTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDM 591 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMGSYE-GSNEIKQHPFFRGINW-ALVRGTAPP 492 I FP I+ + A LI +L +P+ R+G+ + G +I++H +F G NW L +GT P Sbjct: 592 IEFPKKIAKN--AANLIKKLCRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTP 649 Query: 493 KL 498 + Sbjct: 650 PI 651
>KGP1B_BOVIN (P21136) cGMP-dependent protein kinase 1, beta isozyme (EC| 2.7.11.12) (cGK 1 beta) (cGKI-beta) Length = 686 Score = 89.7 bits (221), Expect = 8e-18 Identities = 50/122 (40%), Positives = 73/122 (59%), Gaps = 4/122 (3%) Frame = +1 Query: 145 SFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILH--KD 318 +F GT EY+APEII GH + D+W+LGIL+YE+L G PF G +T+ IL Sbjct: 532 TFCGTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDM 591 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMGSYE-GSNEIKQHPFFRGINW-ALVRGTAPP 492 I FP I+ + A LI +L +P+ R+G+ + G +I++H +F G NW L +GT P Sbjct: 592 IEFPKKIAKN--AANLIKKLCRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTP 649 Query: 493 KL 498 + Sbjct: 650 PI 651
>PDPK1_HUMAN (O15530) 3-phosphoinositide-dependent protein kinase 1 (EC| 2.7.11.1) (hPDK1) Length = 556 Score = 89.4 bits (220), Expect = 1e-17 Identities = 48/132 (36%), Positives = 69/132 (52%), Gaps = 4/132 (3%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKD 318 +NSFVGT +Y++PE++T + D WALG ++Y+++ G PFR F I+ + Sbjct: 239 ANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLE 298 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMG--SYEGSNEIKQHPFFRGINWALVRGTAPP 492 FP AR L+ +LL D R+G EG +K HPFF + W + PP Sbjct: 299 YDFPEKFFPK--ARDLVEKLLVLDATKRLGCEEMEGYGPLKAHPFFESVTWENLHQQTPP 356 Query: 493 KLDA--PLFSKD 522 KL A P S+D Sbjct: 357 KLTAYLPAMSED 368
>KPCZ_HUMAN (Q05513) Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta)| Length = 592 Score = 89.4 bits (220), Expect = 1e-17 Identities = 50/125 (40%), Positives = 71/125 (56%), Gaps = 9/125 (7%) Frame = +1 Query: 127 PMRASNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPF-------RGKTR 285 P +++F GT YIAPEI+ G + +VDWWALG+L++EM+ G +PF T Sbjct: 404 PGDTTSTFCGTPNYIAPEILRGEEYGFSVDWWALGVLMFEMMAGRSPFDIITDNPDMNTE 463 Query: 286 QRTFANILHKDIRFPASISVSLPARQLIYRLLHRDPANRMG--SYEGSNEIKQHPFFRGI 459 F IL K IR P +SV A ++ L++DP R+G G ++IK H FFR I Sbjct: 464 DYLFQVILEKPIRIPRFLSVK--ASHVLKGFLNKDPKERLGCRPQTGFSDIKSHAFFRSI 521 Query: 460 NWALV 474 +W L+ Sbjct: 522 DWDLL 526
>KPC3_CAEEL (Q19266) Protein kinase C-like 3 (EC 2.7.11.13) (Atypical protein| kinase C-3) (aPKC3) Length = 597 Score = 89.4 bits (220), Expect = 1e-17 Identities = 52/133 (39%), Positives = 76/133 (57%), Gaps = 15/133 (11%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPF--------RGKTRQRT 294 +++F GT YIAPEI+ G + +VDWWALG+L++EM+ G +PF T Sbjct: 409 TSTFCGTPNYIAPEILRGDEYGFSVDWWALGVLMFEMMAGRSPFDIVGMQNSEENTEDYL 468 Query: 295 FANILHKDIRFPASISVSLPARQLIYRLLHRDPANRMGS----YEGSNEIKQHPFFRG-I 459 F IL + IR P S+SV A ++ L++DP R+G EG ++K+H FFRG I Sbjct: 469 FQIILERQIRIPRSLSVR--ASGILKGFLNKDPTERLGCKLDINEGLRDMKEHQFFRGFI 526 Query: 460 NWALV--RGTAPP 492 +W + + APP Sbjct: 527 DWEALEQKAVAPP 539
>MASTL_HUMAN (Q96GX5) Microtubule-associated serine/threonine-protein kinase-like| (EC 2.7.11.1) Length = 879 Score = 88.6 bits (218), Expect = 2e-17 Identities = 46/120 (38%), Positives = 67/120 (55%), Gaps = 1/120 (0%) Frame = +1 Query: 151 VGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFP 330 +GT +Y+APE++ G H AVDWWALG+ L+E L G PF +T Q+ F NIL +DI +P Sbjct: 739 LGTPDYLAPELLLGRAHGPAVDWWALGVCLFEFLTGIPPFNDETPQQVFQNILKRDIPWP 798 Query: 331 -ASISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINWALVRGTAPPKLDAP 507 +S A+ + LL D R G E+K+HP F ++W ++ P + P Sbjct: 799 EGEEKLSDNAQSAVEILLTIDDTKR----AGMKELKRHPLFSDVDWENLQHQTMPFIPQP 854
>KPCG_BOVIN (P05128) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| (Fragment) Length = 682 Score = 88.6 bits (218), Expect = 2e-17 Identities = 46/114 (40%), Positives = 66/114 (57%), Gaps = 1/114 (0%) Frame = +1 Query: 127 PMRASNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANI 306 P + +F GT +YIAPEII + +VDWW+ G+LLYEML G PF G+ + F I Sbjct: 493 PGSTTRTFCGTPDYIAPEIIAYQPYGKSVDWWSFGVLLYEMLAGQPPFDGEDEEELFQAI 552 Query: 307 LHKDIRFPASISVSLPARQLIYRLLHRDPANRMGS-YEGSNEIKQHPFFRGINW 465 + + + +P S+S A + L + PA R+GS +G I+ H FFR I+W Sbjct: 553 MEQTVTYPKSLSREAVA--ICKGFLTKHPAKRLGSGPDGEPTIRAHGFFRWIDW 604
>STK38_MOUSE (Q91VJ4) Serine/threonine-protein kinase 38 (EC 2.7.11.1) (NDR1| protein kinase) (Nuclear Dbf2-related kinase 1) Length = 465 Score = 88.6 bits (218), Expect = 2e-17 Identities = 45/113 (39%), Positives = 69/113 (61%), Gaps = 2/113 (1%) Frame = +1 Query: 145 SFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILH--KD 318 S VGT +YIAPE+ G+ DWW+LG+++YEML GY PF +T Q T+ +++ + Sbjct: 281 STVGTPDYIAPEVFMQTGYNKLCDWWSLGVIMYEMLIGYPPFCSETPQETYKKVMNWKET 340 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINWALVR 477 + FP + VS A+ LI R + +R+G+ G EIK + FF G++W +R Sbjct: 341 LTFPPEVPVSEKAKGLILRFC-CEWEHRIGA-PGVEEIKNNLFFEGVDWEHIR 391
>KPC1_APLCA (Q16974) Calcium-dependent protein kinase C (EC 2.7.11.13) (APL I)| Length = 649 Score = 88.6 bits (218), Expect = 2e-17 Identities = 51/134 (38%), Positives = 71/134 (52%), Gaps = 3/134 (2%) Frame = +1 Query: 133 RASNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILH 312 + + +F GT +YIAPEI+ + +VDWWA G+LLYEML G PF G+ + F +I Sbjct: 474 KTTRTFCGTPDYIAPEIVLYQPYGRSVDWWAYGVLLYEMLAGQPPFDGEDEEELFTSITD 533 Query: 313 KDIRFPASISVSLPARQLIYRLLHRDPANRMG-SYEGSNEIKQHPFFRGINWALV--RGT 483 ++ +P ++ S A L LL + PA R+G G +IK FFR I W + R Sbjct: 534 HNVSYPKAL--SREAVSLCKGLLTKTPAKRLGCGPNGERDIKDRAFFRPIQWERIELREV 591 Query: 484 APPKLDAPLFSKDV 525 PP KDV Sbjct: 592 QPPYKPRIKSRKDV 605
>KAPC_DROME (P12370) cAMP-dependent protein kinase catalytic subunit (EC| 2.7.11.11) (PKA C) Length = 352 Score = 88.2 bits (217), Expect = 2e-17 Identities = 51/137 (37%), Positives = 73/137 (53%), Gaps = 1/137 (0%) Frame = +1 Query: 154 GTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPA 333 GT EY+APEII G+ AVDWWALG+L+YEM GY PF + + I+ +RFP+ Sbjct: 202 GTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIQIYEKIVSGKVRFPS 261 Query: 334 SISVSLPARQLIYRLLHRDPANRMGSYE-GSNEIKQHPFFRGINWALVRGTAPPKLDAPL 510 L + L+ LL D R G+ + G N+IK +F +W + K++AP Sbjct: 262 HFGSDL--KDLLRNLLQVDLTKRYGNLKAGVNDIKNQKWFASTDWIAI---FQKKIEAPF 316 Query: 511 FSKDVGKGMGDAAAADN 561 + KG GD + D+ Sbjct: 317 IPR--CKGPGDTSNFDD 331
>KPCI_BRARE (Q90XF2) Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota)| (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota) (Heart and soul protein) Length = 588 Score = 87.8 bits (216), Expect = 3e-17 Identities = 50/135 (37%), Positives = 74/135 (54%), Gaps = 13/135 (9%) Frame = +1 Query: 127 PMRASNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPF---------RGK 279 P +++F GT YIAPEI+ G + +VDWWALG+L++EM+ G +PF Sbjct: 398 PGDTTSTFCGTPNYIAPEILRGEDYGFSVDWWALGVLMFEMMAGRSPFDIVGSSDNPDQN 457 Query: 280 TRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDPANRMGSY--EGSNEIKQHPFFR 453 T F IL K IR P S+SV A ++ L+++ R+G + G +I HPFFR Sbjct: 458 TEDYLFQVILEKQIRIPRSLSVK--AASVLKGFLNKESKERLGCHPQTGFADIMAHPFFR 515 Query: 454 GINWALV--RGTAPP 492 ++W L+ + PP Sbjct: 516 NVDWDLMEQKQVVPP 530
>KPCL_RAT (Q64617) Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta)| (PKC-L) Length = 683 Score = 87.8 bits (216), Expect = 3e-17 Identities = 46/120 (38%), Positives = 70/120 (58%), Gaps = 4/120 (3%) Frame = +1 Query: 145 SFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIR 324 +F GT +YIAPEI+ + AVDWWA+G+LLYEML G+ PF + F IL+ ++ Sbjct: 513 TFCGTPDYIAPEILQEMLYGPAVDWWAMGVLLYEMLCGHAPFEAENEDDLFEAILNDEVV 572 Query: 325 FPASISVSLPARQLIYRLLHRDPANRMGSYE--GSNEIKQHPFFRGINWALV--RGTAPP 492 +P + A ++ + ++P R+GS G +EI +HPFF+ I+W + R PP Sbjct: 573 YPTWLHED--ATGILKSFMTKNPTMRLGSLTQGGEHEILRHPFFKEIDWVQLNHRQLEPP 630
>KPCG_HUMAN (P05129) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| Length = 697 Score = 87.8 bits (216), Expect = 3e-17 Identities = 49/124 (39%), Positives = 69/124 (55%), Gaps = 2/124 (1%) Frame = +1 Query: 127 PMRASNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANI 306 P + +F GT +YIAPEII + +VDWW+ G+LLYEML G PF G+ + F I Sbjct: 508 PGTTTRTFCGTPDYIAPEIIAYQPYGKSVDWWSFGVLLYEMLAGQPPFDGEDEEELFQAI 567 Query: 307 LHKDIRFPASISVSLPARQLIYRLLHRDPANRMGS-YEGSNEIKQHPFFRGINW-ALVRG 480 + + + +P S+S A + L + P R+GS +G I+ H FFR I+W L R Sbjct: 568 MEQTVTYPKSLSREAVA--ICKGFLTKHPGKRLGSGPDGEPTIRAHGFFRWIDWERLERL 625 Query: 481 TAPP 492 PP Sbjct: 626 EIPP 629
>KAPC_CAEEL (P21137) cAMP-dependent protein kinase catalytic subunit (EC| 2.7.11.11) (PKA C) Length = 404 Score = 87.4 bits (215), Expect = 4e-17 Identities = 49/128 (38%), Positives = 68/128 (53%), Gaps = 1/128 (0%) Frame = +1 Query: 154 GTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPA 333 GT EY+APEII G+ AVDWWALG+L+YEM GY PF + + I+ ++FP+ Sbjct: 238 GTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVKFPS 297 Query: 334 SISVSLPARQLIYRLLHRDPANRMGSYE-GSNEIKQHPFFRGINWALVRGTAPPKLDAPL 510 S L + L+ LL D R G+ + G +IK H +F +W + K+ P Sbjct: 298 HFSNEL--KDLLKNLLQVDLTKRYGNLKNGVADIKNHKWFGSTDWIAI---YQKKITPPS 352 Query: 511 FSKDVGKG 534 FSK G Sbjct: 353 FSKGESNG 360
>KGP2_HUMAN (Q13237) cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2)| (cGKII) (Type II cGMP-dependent protein kinase) Length = 762 Score = 87.4 bits (215), Expect = 4e-17 Identities = 44/117 (37%), Positives = 68/117 (58%), Gaps = 1/117 (0%) Frame = +1 Query: 145 SFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIR 324 +F GT EY+APE+I GH +VD+W+LGIL+YE+L G PF G + T+ IL + Sbjct: 609 TFCGTPEYVAPEVILNKGHDFSVDFWSLGILVYELLTGNPPFSGVDQMMTYNLILKGIEK 668 Query: 325 FPASISVSLPARQLIYRLLHRDPANRMGSYE-GSNEIKQHPFFRGINWALVRGTAPP 492 ++ LI RL ++P R+G+ + G N+IK+H + G NW ++ + P Sbjct: 669 MDFPRKITRRPEDLIRRLCRQNPTERLGNLKNGINDIKKHRWLNGFNWEGLKARSLP 725
>KPCL_HUMAN (P24723) Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta)| (PKC-L) Length = 682 Score = 87.0 bits (214), Expect = 5e-17 Identities = 46/120 (38%), Positives = 70/120 (58%), Gaps = 4/120 (3%) Frame = +1 Query: 145 SFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIR 324 +F GT +YIAPEI+ + AVDWWA+G+LLYEML G+ PF + F IL+ ++ Sbjct: 512 TFCGTPDYIAPEILQEMLYGPAVDWWAMGVLLYEMLCGHAPFEAENEDDLFEAILNDEVV 571 Query: 325 FPASISVSLPARQLIYRLLHRDPANRMGSYE--GSNEIKQHPFFRGINWALV--RGTAPP 492 +P + A ++ + ++P R+GS G + I +HPFF+ I+WA + R PP Sbjct: 572 YPTWLHED--ATGILKSFMTKNPTMRLGSLTQGGEHAILRHPFFKEIDWAQLNHRQIEPP 629
>KPCG_RAT (P63319) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| Length = 697 Score = 87.0 bits (214), Expect = 5e-17 Identities = 45/114 (39%), Positives = 65/114 (57%), Gaps = 1/114 (0%) Frame = +1 Query: 127 PMRASNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANI 306 P + +F GT +YIAPEII + +VDWW+ G+LLYEML G PF G+ + F I Sbjct: 508 PGSTTRTFCGTPDYIAPEIIAYQPYGKSVDWWSFGVLLYEMLAGQPPFDGEDEEELFQAI 567 Query: 307 LHKDIRFPASISVSLPARQLIYRLLHRDPANRMGS-YEGSNEIKQHPFFRGINW 465 + + + +P S+S A + L + P R+GS +G I+ H FFR I+W Sbjct: 568 MEQTVTYPKSLSREAVA--ICKGFLTKHPGKRLGSGPDGEPTIRAHGFFRWIDW 619
>KPCG_RABIT (P10829) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| (PKC-delta) Length = 697 Score = 87.0 bits (214), Expect = 5e-17 Identities = 45/114 (39%), Positives = 65/114 (57%), Gaps = 1/114 (0%) Frame = +1 Query: 127 PMRASNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANI 306 P + +F GT +YIAPEII + +VDWW+ G+LLYEML G PF G+ + F I Sbjct: 508 PGTTTRTFCGTPDYIAPEIIAYQPYGKSVDWWSFGVLLYEMLAGQPPFDGEDEEELFQAI 567 Query: 307 LHKDIRFPASISVSLPARQLIYRLLHRDPANRMGS-YEGSNEIKQHPFFRGINW 465 + + + +P S+S A + L + P R+GS +G I+ H FFR I+W Sbjct: 568 MEQTVTYPKSLSREAVA--ICKGFLTKHPGKRLGSGPDGEPTIRAHGFFRWIDW 619
>KPCG_MOUSE (P63318) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| Length = 697 Score = 87.0 bits (214), Expect = 5e-17 Identities = 45/114 (39%), Positives = 65/114 (57%), Gaps = 1/114 (0%) Frame = +1 Query: 127 PMRASNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANI 306 P + +F GT +YIAPEII + +VDWW+ G+LLYEML G PF G+ + F I Sbjct: 508 PGSTTRTFCGTPDYIAPEIIAYQPYGKSVDWWSFGVLLYEMLAGQPPFDGEDEEELFQAI 567 Query: 307 LHKDIRFPASISVSLPARQLIYRLLHRDPANRMGS-YEGSNEIKQHPFFRGINW 465 + + + +P S+S A + L + P R+GS +G I+ H FFR I+W Sbjct: 568 MEQTVTYPKSLSREAVA--ICKGFLTKHPGKRLGSGPDGEPTIRAHGFFRWIDW 619
>KGP2_RAT (Q64595) cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2)| (cGKII) (Type II cGMP-dependent protein kinase) Length = 762 Score = 87.0 bits (214), Expect = 5e-17 Identities = 44/117 (37%), Positives = 68/117 (58%), Gaps = 1/117 (0%) Frame = +1 Query: 145 SFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIR 324 +F GT EY+APE+I GH +VD+W+LGIL+YE+L G PF G + T+ IL + Sbjct: 609 TFCGTPEYVAPEVILNKGHDFSVDFWSLGILVYELLTGNPPFSGIDQMMTYNLILKGIEK 668 Query: 325 FPASISVSLPARQLIYRLLHRDPANRMGSYE-GSNEIKQHPFFRGINWALVRGTAPP 492 ++ LI RL ++P R+G+ + G N+IK+H + G NW ++ + P Sbjct: 669 MDFPRKITRRPEDLIRRLCRQNPTERLGNLKNGINDIKKHRWLNGFNWEGLKARSLP 725
>KGP2_MOUSE (Q61410) cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2)| (cGKII) (Type II cGMP-dependent protein kinase) Length = 762 Score = 87.0 bits (214), Expect = 5e-17 Identities = 44/117 (37%), Positives = 68/117 (58%), Gaps = 1/117 (0%) Frame = +1 Query: 145 SFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIR 324 +F GT EY+APE+I GH +VD+W+LGIL+YE+L G PF G + T+ IL + Sbjct: 609 TFCGTPEYVAPEVILNKGHDFSVDFWSLGILVYELLTGNPPFSGIDQMMTYNLILKGIEK 668 Query: 325 FPASISVSLPARQLIYRLLHRDPANRMGSYE-GSNEIKQHPFFRGINWALVRGTAPP 492 ++ LI RL ++P R+G+ + G N+IK+H + G NW ++ + P Sbjct: 669 MDFPRKITRRPEDLIRRLCRQNPTERLGNLKNGINDIKKHRWLNGFNWEGLKARSLP 725
>AKT1_CAEEL (Q17941) Serine/threonine-protein kinase akt-1 (EC 2.7.11.1)| (Protein kinase B akt-1) (PKB akt-1) Length = 541 Score = 87.0 bits (214), Expect = 5e-17 Identities = 43/110 (39%), Positives = 67/110 (60%), Gaps = 1/110 (0%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKD 318 +++F GT EY+APE++ + VDWW +G+++YEM+ G PF K + F I+ D Sbjct: 348 TSTFCGTPEYLAPEVLDDHDYGRCVDWWGVGVVMYEMMCGRLPFYSKDHNKLFELIMAGD 407 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRM-GSYEGSNEIKQHPFFRGINW 465 +RFP+ +S AR L+ LL +DP R+ G E + EI + FFR ++W Sbjct: 408 LRFPSKLSQE--ARTLLTGLLVKDPTQRLGGGPEDALEICRADFFRTVDW 455
>KPC1B_CAEEL (P34885) Protein kinase C-like 1B (EC 2.7.11.13) (PKC1B)| Length = 707 Score = 87.0 bits (214), Expect = 5e-17 Identities = 51/143 (35%), Positives = 76/143 (53%), Gaps = 12/143 (8%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKD 318 +++F GT +YIAPEI+ + +VDWWALG+L+YEM+ G PF F IL+ D Sbjct: 534 TSTFCGTPDYIAPEILQEMEYGVSVDWWALGVLMYEMMAGQPPFEADNEDDLFEAILNDD 593 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMG---SYEGSNEIKQHPFFRGINWALV--RGT 483 + +P + +S A ++ + ++ R+G S G + I+ HPFFR I+W + R Sbjct: 594 VLYP--VWLSKEAVNILKAFMTKNAGKRLGCVVSQGGEDAIRAHPFFREIDWDALESRQV 651 Query: 484 APP-------KLDAPLFSKDVGK 531 PP K DA F D K Sbjct: 652 KPPFKPKIKSKRDANNFDSDFTK 674
>KPC1_CANAL (P43057) Protein kinase C-like 1 (EC 2.7.11.13) (PKC 1)| Length = 1097 Score = 86.7 bits (213), Expect = 6e-17 Identities = 40/110 (36%), Positives = 71/110 (64%), Gaps = 1/110 (0%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKD 318 +++F GT E++APEI+ G + +VDWWA G+LL++ML +PF+G F I + + Sbjct: 927 TSTFCGTPEFMAPEIVAGKAYDRSVDWWAFGVLLFQMLLCQSPFKGDDEDDIFNAIENDE 986 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMGS-YEGSNEIKQHPFFRGINW 465 +++P I++S ++ LL +DP+ R+GS + + EI +HP+F +N+ Sbjct: 987 VKYP--INLSRQTVLVLQALLTKDPSQRLGSGPKDAEEIMEHPYFHDVNF 1034
>KPC2_DROME (P13677) Protein kinase C, eye isozyme (EC 2.7.11.13) (PKC)| (dPKC53E(EY)) (Protein INAC) (Inactivation no after-potential C protein) (Photoreceptor-specific PKC) (Eye-PKC) Length = 700 Score = 86.3 bits (212), Expect = 8e-17 Identities = 43/112 (38%), Positives = 61/112 (54%), Gaps = 1/112 (0%) Frame = +1 Query: 133 RASNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILH 312 + + +F GT Y+APEI++ ++ A DWW+ G+LL+E + G PF G F NI Sbjct: 525 QTTRTFCGTPNYMAPEIVSYDPYSIAADWWSFGVLLFEFMAGQAPFEGDDETTVFRNIKD 584 Query: 313 KDIRFPASISVSLPARQLIYRLLHRDPANRMGSYE-GSNEIKQHPFFRGINW 465 K FP SV A +I L + P NR+G+ EI HPFFR ++W Sbjct: 585 KKAVFPKHFSVE--AMDIITSFLTKKPNNRLGAGRYARQEITTHPFFRNVDW 634
>LATS1_HUMAN (O95835) Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large| tumor suppressor homolog 1) (WARTS protein kinase) (h-warts) Length = 1130 Score = 85.1 bits (209), Expect = 2e-16 Identities = 43/112 (38%), Positives = 68/112 (60%), Gaps = 2/112 (1%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILH-- 312 ++S VGT YIAPE++ G+T DWW++G++L+EML G PF +T T +++ Sbjct: 907 AHSLVGTPNYIAPEVLLRTGYTQLCDWWSVGVILFEMLVGQPPFLAQTPLETQMKVINWQ 966 Query: 313 KDIRFPASISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINWA 468 + P +S A LI +L R P +R+G G++EIK HPFF+ I+++ Sbjct: 967 TSLHIPPQAKLSPEASDLIIKLC-RGPEDRLGK-NGADEIKAHPFFKTIDFS 1016
>KPC1_NEUCR (P87253) Protein kinase C-like (EC 2.7.11.13)| Length = 1142 Score = 85.1 bits (209), Expect = 2e-16 Identities = 43/110 (39%), Positives = 66/110 (60%), Gaps = 1/110 (0%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKD 318 +++F GT E++APEI+ + AVDWWA G+L+Y+ML +PFRG+ + IL + Sbjct: 974 TSTFCGTPEFMAPEILLDKKYGRAVDWWAFGVLIYQMLLQQSPFRGEDEDEIYDAILADE 1033 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMGS-YEGSNEIKQHPFFRGINW 465 +P I + + ++ +LL R+P R+GS + EI PFFR INW Sbjct: 1034 PLYP--IHMPRDSVSILQKLLTREPDQRLGSGPTDAQEIMSQPFFRNINW 1081
>KPC1_TRIRE (Q99014) Protein kinase C-like (EC 2.7.11.13)| Length = 1139 Score = 84.7 bits (208), Expect = 2e-16 Identities = 42/110 (38%), Positives = 66/110 (60%), Gaps = 1/110 (0%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKD 318 +++F GT E++APEI+ + AVDWWA G+L+Y+ML +PFRG+ + IL + Sbjct: 971 TSTFCGTPEFMAPEILLDKKYGRAVDWWAFGVLIYQMLLQQSPFRGEDEDEIYDAILADE 1030 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMGS-YEGSNEIKQHPFFRGINW 465 +P I + + ++ +LL R+P R+GS + E+ PFFR INW Sbjct: 1031 PLYP--IHMPRDSVSILQKLLTREPDQRLGSGPTDAQEVMSQPFFRNINW 1078
>MRCKA_HUMAN (Q5VT25) Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1)| (CDC42-binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) (DMPK-like alpha Length = 1732 Score = 84.7 bits (208), Expect = 2e-16 Identities = 52/126 (41%), Positives = 76/126 (60%), Gaps = 8/126 (6%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIIT----GAG-HTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFAN 303 S+ VGT +YI+PEI+ G G + DWW+LG+ +YEMLYG TPF ++ T+ Sbjct: 234 SSVAVGTPDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGK 293 Query: 304 IL-HKD-IRFPASIS-VSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINWALV 474 I+ HK+ +FPA ++ VS A+ LI RL+ +R+G G + K+HPFF GI+W + Sbjct: 294 IMNHKERFQFPAQVTDVSENAKDLIRRLI-CSREHRLGQ-NGIEDFKKHPFFSGIDWDNI 351 Query: 475 RGTAPP 492 R P Sbjct: 352 RNCEAP 357
>COT1_NEUCR (P38679) Serine/threonine-protein kinase cot-1 (EC 2.7.11.1)| (Colonial temperature-sensitive 1) Length = 598 Score = 84.7 bits (208), Expect = 2e-16 Identities = 47/118 (39%), Positives = 70/118 (59%), Gaps = 2/118 (1%) Frame = +1 Query: 145 SFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILH--KD 318 S VGT +YIAPEI TG G++ DWW+LG +++E L G+ PF + T+ I++ Sbjct: 417 STVGTPDYIAPEIFTGHGYSFDCDWWSLGTIMFECLVGWPPFCAEDSHDTYRKIVNWRHS 476 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINWALVRGTAPP 492 + FP I++ + A LI R L + NR+G G++EIK H FFRG+ + +R P Sbjct: 477 LYFPDDITLGVDAENLI-RSLICNTENRLGR-GGAHEIKSHAFFRGVEFDSLRRIRAP 532
>KGP24_DROME (Q03043) cGMP-dependent protein kinase, isozyme 2 forms| cD4/T1/T3A/T3B (EC 2.7.11.12) (CGK) (Foraging protein) Length = 1088 Score = 84.7 bits (208), Expect = 2e-16 Identities = 47/115 (40%), Positives = 70/115 (60%), Gaps = 4/115 (3%) Frame = +1 Query: 133 RASNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILH 312 R + +F GT EY+APE+I GH + D+W+LG+L++E+L G PF G RT+ NI+ Sbjct: 930 RKTWTFCGTPEYVAPEVILNRGHDISADYWSLGVLMFELLTGTPPFTGSDPMRTY-NIIL 988 Query: 313 KD---IRFPASISVSLPARQLIYRLLHRDPANRMGSYEGS-NEIKQHPFFRGINW 465 K I FP +I+ + A LI +L +PA R+G G +EI++H +F G W Sbjct: 989 KGIDAIEFPRNITRN--ASNLIKKLCRDNPAERLGYQRGGISEIQKHKWFDGFYW 1041
>KPC2_APLCA (Q16975) Calcium-independent protein kinase C (EC 2.7.11.13) (APL| II) Length = 743 Score = 84.7 bits (208), Expect = 2e-16 Identities = 51/143 (35%), Positives = 79/143 (55%), Gaps = 13/143 (9%) Frame = +1 Query: 133 RASNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILH 312 + + +F GT +YIAPEI+ + ++VDWWALG+L+YEM+ G PF F +ILH Sbjct: 557 KLTQTFCGTPDYIAPEILQELKYDASVDWWALGVLMYEMMAGQPPFEADNEDDLFESILH 616 Query: 313 KDIRFPASISVSLPARQLIYRLLHRDPANRMG--SYEGSNE-IKQHPFF-RGINWALV-- 474 D+ +P + +S A ++ + ++PA R+G + +G + I HPFF I+W + Sbjct: 617 DDVLYP--VWLSKEAVSILKGFMTKNPAKRLGCVTTQGCEKAILVHPFFHEKIDWEALEQ 674 Query: 475 RGTAPP-------KLDAPLFSKD 522 R PP K DA F +D Sbjct: 675 RKVKPPFKPKIKNKTDANNFDRD 697
>KPC1_LYTPI (Q25378) Protein kinase C (EC 2.7.11.13)| Length = 658 Score = 84.7 bits (208), Expect = 2e-16 Identities = 44/110 (40%), Positives = 63/110 (57%), Gaps = 1/110 (0%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKD 318 + +F GT +YIAPEI+ + AVDWWA G+LLYEML G PF G+ F +I+ Sbjct: 481 TRTFCGTPDYIAPEIVAYQPYGKAVDWWAFGVLLYEMLAGQPPFDGEDEDELFQSIMEHV 540 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMGS-YEGSNEIKQHPFFRGINW 465 +P S+S + + L + P R+GS G +I++H FFR I+W Sbjct: 541 PSYPK--SMSRESVTMCKGFLTKHPGKRLGSGPTGEQDIREHQFFRRIDW 588
>KGP25_DROME (P32023) cGMP-dependent protein kinase, isozyme 2 forms cD5/T2 (EC| 2.7.11.12) (CGK) (Foraging protein) Length = 934 Score = 84.7 bits (208), Expect = 2e-16 Identities = 47/115 (40%), Positives = 70/115 (60%), Gaps = 4/115 (3%) Frame = +1 Query: 133 RASNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILH 312 R + +F GT EY+APE+I GH + D+W+LG+L++E+L G PF G RT+ NI+ Sbjct: 776 RKTWTFCGTPEYVAPEVILNRGHDISADYWSLGVLMFELLTGTPPFTGSDPMRTY-NIIL 834 Query: 313 KD---IRFPASISVSLPARQLIYRLLHRDPANRMGSYEGS-NEIKQHPFFRGINW 465 K I FP +I+ + A LI +L +PA R+G G +EI++H +F G W Sbjct: 835 KGIDAIEFPRNITRN--ASNLIKKLCRDNPAERLGYQRGGISEIQKHKWFDGFYW 887
>KPC1_COCHE (O42632) Protein kinase C-like (EC 2.7.11.13)| Length = 1174 Score = 84.7 bits (208), Expect = 2e-16 Identities = 43/110 (39%), Positives = 66/110 (60%), Gaps = 1/110 (0%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKD 318 +++F GT E++APEI+ + AVDWWA G+L+Y+ML +PFRG+ + IL + Sbjct: 1006 TSTFCGTPEFMAPEILLDKKYGRAVDWWAFGVLIYQMLLQQSPFRGEDEDEIYDAILADE 1065 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMGS-YEGSNEIKQHPFFRGINW 465 +P I + + ++ +LL R+P R+GS + EI H FFR INW Sbjct: 1066 PLYP--IHMPRDSVSILQKLLTREPEMRLGSGPTDAQEIMSHAFFRNINW 1113
>MRCKG_MOUSE (Q80UW5) Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1)| (CDC42-binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma Length = 1551 Score = 84.7 bits (208), Expect = 2e-16 Identities = 54/135 (40%), Positives = 82/135 (60%), Gaps = 11/135 (8%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIIT----GAGHTSA-VDWWALGILLYEMLYGYTPFRGKTRQRTFAN 303 S+ VGT +YI+PEI+ G GH DWW+LG+ YE+L+G TPF ++ T+ Sbjct: 228 SSVAVGTPDYISPEILQAMEEGKGHYGPQCDWWSLGVCAYELLFGETPFYAESLVETYGK 287 Query: 304 IL-HKD-IRFPASIS-VSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINW-AL 471 I+ H+D ++FPA ++ V A+ LI +LL R R+G G ++ ++HPFF G++W L Sbjct: 288 IMNHEDHLQFPADVTDVPASAQDLIRQLLCRQ-EERLGR-GGLDDFRKHPFFEGVDWERL 345 Query: 472 VRGTAP--PKLDAPL 510 TAP P+L P+ Sbjct: 346 ATSTAPYIPELRGPM 360
>CBK1_EMENI (P0C1B1) Serine/threonine-protein kinase cbk1 (EC 2.7.11.1)| Length = 884 Score = 84.3 bits (207), Expect = 3e-16 Identities = 52/157 (33%), Positives = 72/157 (45%), Gaps = 39/157 (24%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANI---- 306 + S VGT +Y+APE+I G + DWW+LG++LYE LYG+TPF + R +T I Sbjct: 610 ARSVVGTSQYMAPEVIRGHPYDGRCDWWSLGVILYECLYGFTPFASEDRHQTKLKIHRHL 669 Query: 307 --LHKDIRFPASISVSLPARQLIYRLLHR--------------------------DPANR 402 L+ + P VS A +I LL P + Sbjct: 670 QTLYFPVHRPTDKLVSADAIDVINSLLQEKEFRLSSPKYKQNDAISSKPAKCSFYKPDSS 729 Query: 403 MGSYEG-------SNEIKQHPFFRGINWALVRGTAPP 492 SY+G + +IK H FFRGINW + T+PP Sbjct: 730 NPSYQGHYVYPDDATDIKSHRFFRGINWEQIHRTSPP 766
>KPC1_ASPNG (Q00078) Protein kinase C-like (EC 2.7.11.13)| Length = 1096 Score = 84.0 bits (206), Expect = 4e-16 Identities = 42/110 (38%), Positives = 66/110 (60%), Gaps = 1/110 (0%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKD 318 +++F GT E++APEI+ + AVDWWA G+L+Y+ML +PFRG+ + IL + Sbjct: 928 TSTFCGTPEFMAPEILLDKRYGRAVDWWAFGVLIYQMLLQQSPFRGEDEDEIYDAILADE 987 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMGS-YEGSNEIKQHPFFRGINW 465 +P I + + ++ +LL R+P R+GS + E+ H FFR INW Sbjct: 988 PLYP--IHMPRDSVSILQKLLTREPELRLGSGPTDAQEVMSHAFFRNINW 1035
>KPC1_YEAST (P24583) Protein kinase C-like 1 (EC 2.7.11.13) (PKC 1)| Length = 1151 Score = 83.2 bits (204), Expect = 7e-16 Identities = 42/110 (38%), Positives = 66/110 (60%), Gaps = 1/110 (0%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKD 318 +++F GT E++APEI+ +T AVDWWA G+LLY+ML +PF G F IL + Sbjct: 981 TSTFCGTPEFMAPEILKEQEYTKAVDWWAFGVLLYQMLLCQSPFSGDDEDEVFNAILTDE 1040 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMGS-YEGSNEIKQHPFFRGINW 465 +P ++ + Q+ LL +DP R+G+ ++E+ + PFFR IN+ Sbjct: 1041 PLYPIDMAGEIV--QIFQGLLTKDPEKRLGAGPRDADEVMEEPFFRNINF 1088
>MRCKA_RAT (O54874) Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1)| (CDC42-binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) Length = 1732 Score = 83.2 bits (204), Expect = 7e-16 Identities = 51/126 (40%), Positives = 75/126 (59%), Gaps = 8/126 (6%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIIT----GAG-HTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFAN 303 S+ VGT +YI+PEI+ G G + DWW+LG+ +YEMLYG TPF ++ T+ Sbjct: 234 SSVAVGTPDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGK 293 Query: 304 IL-HKD-IRFPASIS-VSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINWALV 474 I+ HK+ +FP ++ VS A+ LI RL+ +R+G G + K+HPFF GI+W + Sbjct: 294 IMNHKERFQFPTQVTDVSENAKDLIRRLI-CSREHRLGQ-NGIEDFKKHPFFSGIDWDNI 351 Query: 475 RGTAPP 492 R P Sbjct: 352 RNCEAP 357
>GRK6_HUMAN (P43250) G protein-coupled receptor kinase 6 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK6) Length = 576 Score = 83.2 bits (204), Expect = 7e-16 Identities = 47/108 (43%), Positives = 65/108 (60%), Gaps = 3/108 (2%) Frame = +1 Query: 151 VGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPF--RGKTRQRTFANILHKDIR 324 VGT Y+APE++ +T + DWWALG LLYEM+ G +PF R K +R L K++ Sbjct: 346 VGTVGYMAPEVVKNERYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVP 405 Query: 325 FPASISVSLPARQLIYRLLHRDPANRMGSYEGS-NEIKQHPFFRGINW 465 S S AR L +LL +DPA R+G GS E+K+HP F+ +N+ Sbjct: 406 EEYSERFSPQARSLCSQLLCKDPAERLGCRGGSAREVKEHPLFKKLNF 453
>KGP1_DROME (Q03042) cGMP-dependent protein kinase, isozyme 1 (EC 2.7.11.12)| (CGK) Length = 768 Score = 82.8 bits (203), Expect = 9e-16 Identities = 50/110 (45%), Positives = 64/110 (58%), Gaps = 3/110 (2%) Frame = +1 Query: 145 SFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILH--KD 318 +F GT EY+APEII GH AVD+WALGIL++E+L G PF +T+ IL Sbjct: 615 TFCGTPEYVAPEIILNKGHDRAVDYWALGILIHELLNGTPPFSAPDPMQTYNLILKGIDM 674 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMGSYEGS-NEIKQHPFFRGINW 465 I FP I S A QLI RL P+ R+G G +IK+H +F G +W Sbjct: 675 IAFPKHI--SRWAVQLIKRLCRDVPSERLGYQTGGIQDIKKHKWFLGFDW 722
>LATS1_MOUSE (Q8BYR2) Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large| tumor suppressor homolog 1) (WARTS protein kinase) Length = 1129 Score = 82.8 bits (203), Expect = 9e-16 Identities = 43/112 (38%), Positives = 66/112 (58%), Gaps = 2/112 (1%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANIL--H 312 ++S VGT YIAPE++ G+T DWW++G++L EML G PF +T T ++ Sbjct: 906 AHSLVGTPNYIAPEVLLRTGYTQLCDWWSVGVILCEMLVGQPPFLAQTPLETQMKVIIWQ 965 Query: 313 KDIRFPASISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINWA 468 + P +S A LI +L R P +R+G G++EIK HPFF+ I+++ Sbjct: 966 TSLHIPPQAKLSPEASDLIIKLC-RGPEDRLGK-NGADEIKAHPFFKTIDFS 1015
>AKT2_CAEEL (Q9XTG7) Serine/threonine-protein kinase akt-2 (EC 2.7.11.1)| (Protein kinase B akt-2) (PKB akt-2) Length = 528 Score = 82.4 bits (202), Expect = 1e-15 Identities = 43/121 (35%), Positives = 70/121 (57%), Gaps = 3/121 (2%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKD 318 +++F GT EY+APE+I + +VDWW +G+++YEM+ G PF K + F I D Sbjct: 335 TSTFCGTPEYLAPEVIEDIDYDRSVDWWGVGVVMYEMMCGRLPFSAKENGKLFELITTCD 394 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMGS-YEGSNEIKQHPFFRGINW--ALVRGTAP 489 ++FP +S A L+ LL R PA R+G+ + + E+ + FF+ ++W L + P Sbjct: 395 LKFPNRLSPE--AVTLLSGLLERVPAKRLGAGPDDAREVSRAEFFKDVDWEATLRKEVEP 452 Query: 490 P 492 P Sbjct: 453 P 453
>GRK6_MOUSE (O70293) G protein-coupled receptor kinase 6 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK6) Length = 576 Score = 82.4 bits (202), Expect = 1e-15 Identities = 45/108 (41%), Positives = 65/108 (60%), Gaps = 3/108 (2%) Frame = +1 Query: 151 VGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPF--RGKTRQRTFANILHKDIR 324 VGT Y+APE++ +T + DWWALG LLYEM+ G +PF R K +R L K++ Sbjct: 346 VGTVGYMAPEVVRNERYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVA 405 Query: 325 FPASISVSLPARQLIYRLLHRDPANRMGSY-EGSNEIKQHPFFRGINW 465 + S AR L +LL +DPA R+G G+ E+K+HP F+ +N+ Sbjct: 406 EEYTDRFSSQARSLCSQLLSKDPAERLGCRGGGAREVKEHPLFKKLNF 453
>PSK1_SCHPO (Q12706) Serine/threonine-protein kinase psk1 (EC 2.7.11.22)| Length = 436 Score = 82.4 bits (202), Expect = 1e-15 Identities = 45/122 (36%), Positives = 68/122 (55%), Gaps = 4/122 (3%) Frame = +1 Query: 145 SFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIR 324 SFVGTEEY APEI+ + AVDWW++GIL++++L G PF +R I Sbjct: 248 SFVGTEEYCAPEILLEQPYDHAVDWWSMGILIFDLLTGSPPFTANNHKRIMEKITRAKPN 307 Query: 325 FPASISVSLPARQLIYRLLHRDPANRMGS---YEGSNEIKQHPFFRGINW-ALVRGTAPP 492 P V+ AR +I + L ++P R+G+ +G + IK+H +R I+W L + PP Sbjct: 308 IP--FYVTSDARDIINKFLKKNPKQRLGADGPEKGYDAIKKHRIYRRIDWNKLEKRMLPP 365 Query: 493 KL 498 + Sbjct: 366 PI 367
>MRCKB_RAT (Q7TT49) Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1)| (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta) Length = 1713 Score = 82.0 bits (201), Expect = 2e-15 Identities = 49/126 (38%), Positives = 73/126 (57%), Gaps = 8/126 (6%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIIT----GAG-HTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFAN 303 S+ VGT +YI+PEI+ G G + DWW+LG+ +YEMLYG TPF ++ T+ Sbjct: 233 SSVAVGTPDYISPEILQAMEDGMGKYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGK 292 Query: 304 ILHKDIR--FPASIS-VSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINWALV 474 I++ + R FP+ ++ VS A+ LI RL+ R+G G + K+H FF G+NW + Sbjct: 293 IMNHEERFQFPSHVTDVSEEAKDLIQRLI-CSRERRLGQ-NGIEDFKKHAFFEGLNWENI 350 Query: 475 RGTAPP 492 R P Sbjct: 351 RNLEAP 356
>MRCKB_MOUSE (Q7TT50) Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1)| (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta) Length = 1713 Score = 82.0 bits (201), Expect = 2e-15 Identities = 49/126 (38%), Positives = 73/126 (57%), Gaps = 8/126 (6%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIIT----GAG-HTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFAN 303 S+ VGT +YI+PEI+ G G + DWW+LG+ +YEMLYG TPF ++ T+ Sbjct: 233 SSVAVGTPDYISPEILQAMEDGMGKYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGK 292 Query: 304 ILHKDIR--FPASIS-VSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINWALV 474 I++ + R FP+ ++ VS A+ LI RL+ R+G G + K+H FF G+NW + Sbjct: 293 IMNHEERFQFPSHVTDVSEEAKDLIQRLI-CSRERRLGQ-NGIEDFKKHAFFEGLNWENI 350 Query: 475 RGTAPP 492 R P Sbjct: 351 RNLEAP 356
>ROCK2_MOUSE (P70336) Rho-associated protein kinase 2 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 2) (p164 ROCK-2) Length = 1388 Score = 82.0 bits (201), Expect = 2e-15 Identities = 55/146 (37%), Positives = 77/146 (52%), Gaps = 8/146 (5%) Frame = +1 Query: 151 VGTEEYIAPEIITGAG----HTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANIL-HK 315 VGT +YI+PE++ G + DWW++G+ L+EML G TPF + T++ I+ HK Sbjct: 251 VGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLFEMLVGDTPFYADSLVGTYSKIMDHK 310 Query: 316 D-IRFPASISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRG--INWALVRGTA 486 + + FP +S A+ LI L D R+G G EIKQHPFF+ NW +R TA Sbjct: 311 NSLCFPEDTEISKHAKNLICAFL-TDREVRLGR-NGVEEIKQHPFFKNDQWNWDNIRETA 368 Query: 487 PPKLDAPLFSKDVGKGMGDAAAADNG 564 P + P S D+ D D G Sbjct: 369 APVV--PELSSDIDSSNFDDIEDDKG 392
>ROCK2_BOVIN (Q28021) Rho-associated protein kinase 2 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 2) (p164 ROCK-2) Length = 1388 Score = 82.0 bits (201), Expect = 2e-15 Identities = 55/146 (37%), Positives = 77/146 (52%), Gaps = 8/146 (5%) Frame = +1 Query: 151 VGTEEYIAPEIITGAG----HTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANIL-HK 315 VGT +YI+PE++ G + DWW++G+ L+EML G TPF + T++ I+ HK Sbjct: 251 VGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLFEMLVGDTPFYADSLVGTYSKIMDHK 310 Query: 316 D-IRFPASISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRG--INWALVRGTA 486 + + FP +S A+ LI L D R+G G EIKQHPFF+ NW +R TA Sbjct: 311 NSLCFPEDAEISKHAKNLICAFL-TDREVRLGR-NGVEEIKQHPFFKNDQWNWDNIRETA 368 Query: 487 PPKLDAPLFSKDVGKGMGDAAAADNG 564 P + P S D+ D D G Sbjct: 369 APVV--PELSSDIDSSNFDDIEDDKG 392
>MRCKB_HUMAN (Q9Y5S2) Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1)| (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta) Length = 1711 Score = 82.0 bits (201), Expect = 2e-15 Identities = 49/126 (38%), Positives = 73/126 (57%), Gaps = 8/126 (6%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIIT----GAG-HTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFAN 303 S+ VGT +YI+PEI+ G G + DWW+LG+ +YEMLYG TPF ++ T+ Sbjct: 233 SSVAVGTPDYISPEILQAMEDGMGKYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGK 292 Query: 304 ILHKDIR--FPASIS-VSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINWALV 474 I++ + R FP+ ++ VS A+ LI RL+ R+G G + K+H FF G+NW + Sbjct: 293 IMNHEERFQFPSHVTDVSEEAKDLIQRLI-CSRERRLGQ-NGIEDFKKHAFFEGLNWENI 350 Query: 475 RGTAPP 492 R P Sbjct: 351 RNLEAP 356
>MRCKG_HUMAN (Q6DT37) Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1)| (CDC42-binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma Length = 1551 Score = 82.0 bits (201), Expect = 2e-15 Identities = 53/135 (39%), Positives = 79/135 (58%), Gaps = 11/135 (8%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIIT----GAGHTSA-VDWWALGILLYEMLYGYTPFRGKTRQRTFAN 303 S+ VGT +YI+PEI+ G GH DWW+LG+ YE+L+G TPF ++ T+ Sbjct: 228 SSVAVGTPDYISPEILQAMEEGKGHYGPQCDWWSLGVCAYELLFGETPFYAESLVETYGK 287 Query: 304 IL-HKD-IRFPASI-SVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINW-AL 471 I+ H+D ++FP + V A+ LI +LL R R+G G ++ + HPFF G++W L Sbjct: 288 IMNHEDHLQFPPDVPDVPASAQDLIRQLLCRQ-EERLGR-GGLDDFRNHPFFEGVDWERL 345 Query: 472 VRGTAP--PKLDAPL 510 TAP P+L P+ Sbjct: 346 ASSTAPYIPELRGPM 360
>LATS2_HUMAN (Q9NRM7) Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Large| tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Kinase phosphorylated during mitosis protein) (Warts-like kinase) Length = 1088 Score = 80.9 bits (198), Expect = 4e-15 Identities = 41/112 (36%), Positives = 67/112 (59%), Gaps = 2/112 (1%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILH-- 312 ++S VGT YIAPE++ G+T DWW++G++L+EML G PF T T +++ Sbjct: 870 AHSLVGTPNYIAPEVLLRKGYTQLCDWWSVGVILFEMLVGQPPFLAPTPTETQLKVINWE 929 Query: 313 KDIRFPASISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINWA 468 + PA + +S AR LI +L +R+G G++++K HPFF I+++ Sbjct: 930 NTLHIPAQVKLSPEARDLITKLC-CSADHRLGR-NGADDLKAHPFFSAIDFS 979
>KS6A1_MOUSE (P18653) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1)| (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 724 Score = 80.5 bits (197), Expect = 5e-15 Identities = 43/108 (39%), Positives = 62/108 (57%), Gaps = 1/108 (0%) Frame = +1 Query: 145 SFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIR 324 SF GT EY+APE++ GHT + DWW+ G+L+ GK R+ T IL + Sbjct: 221 SFCGTVEYMAPEVVNRQGHTHSADWWSYGVLM-----------GKDRKETMTLILKAKLG 269 Query: 325 FPASISVSLPARQLIYRLLHRDPANRMGS-YEGSNEIKQHPFFRGINW 465 P +S A+ L+ L R+PANR+GS +G+ EIK+H F+ I+W Sbjct: 270 MPQFLSTE--AQSLLRALFKRNPANRLGSGPDGAEEIKRHIFYSTIDW 315 Score = 60.5 bits (145), Expect = 5e-09 Identities = 43/120 (35%), Positives = 63/120 (52%), Gaps = 10/120 (8%) Frame = +1 Query: 118 FAEPMRASNSFVGTEEY----IAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTR 285 FA+ +RA N + T Y +APE++ G+ D W+LGILLY ML GYTPF Sbjct: 549 FAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDEGCDIWSLGILLYTMLAGYTPFANGPS 608 Query: 286 QRTFANILHK--DIRFPAS----ISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPF 447 T IL + +F S +VS A+ L+ ++LH DP R+ + ++ QHP+ Sbjct: 609 D-TPEEILTRIGSGKFTLSGGNWNTVSETAKDLVSKMLHVDPHQRL----TAKQVLQHPW 663
>ROCK2_HUMAN (O75116) Rho-associated protein kinase 2 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2) Length = 1388 Score = 80.5 bits (197), Expect = 5e-15 Identities = 54/146 (36%), Positives = 77/146 (52%), Gaps = 8/146 (5%) Frame = +1 Query: 151 VGTEEYIAPEIITGAG----HTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANIL-HK 315 VGT +YI+PE++ G + DWW++G+ LYEML G TPF + T++ I+ HK Sbjct: 251 VGTPDYISPEVLKSQGGDGFYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMDHK 310 Query: 316 D-IRFPASISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRG--INWALVRGTA 486 + + FP +S A+ LI L D R+G G EI+QHPFF+ +W +R TA Sbjct: 311 NSLCFPEDAEISKHAKNLICAFL-TDREVRLGR-NGVEEIRQHPFFKNDQWHWDNIRETA 368 Query: 487 PPKLDAPLFSKDVGKGMGDAAAADNG 564 P + P S D+ D D G Sbjct: 369 APVV--PELSSDIDSSNFDDIEDDKG 392
>GRK2_CAEEL (Q09639) G protein-coupled receptor kinase 2 (EC 2.7.11.16)| Length = 707 Score = 80.5 bits (197), Expect = 5e-15 Identities = 46/121 (38%), Positives = 71/121 (58%), Gaps = 7/121 (5%) Frame = +1 Query: 151 VGTEEYIAPEIIT-GAGHTSAVDWWALGILLYEMLYGYTPFR---GKTRQRTFANILHKD 318 VGT Y+APE++ G + S+ DW++LG +LY++L G++PFR K + L +D Sbjct: 352 VGTHGYMAPEVLAKGVAYDSSADWFSLGCMLYKLLKGHSPFRQHKSKDKNEIDKMTLTQD 411 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMGSY-EGSNEIKQHPFFRGINWALV--RGTAP 489 I P + +S R L+ LL RD +R+G +G E+K+HPFF+ ++W V R P Sbjct: 412 IELP-NEGLSKDCRDLLEGLLKRDVPDRLGCRGKGPTEVKEHPFFKDVDWQTVYLRRMTP 470 Query: 490 P 492 P Sbjct: 471 P 471
>DMPK_HUMAN (Q09013) Myotonin-protein kinase (EC 2.7.11.1) (Myotonic dystrophy| protein kinase) (MDPK) (DM-kinase) (DMK) (DMPK) (MT-PK) Length = 639 Score = 80.1 bits (196), Expect = 6e-15 Identities = 46/124 (37%), Positives = 65/124 (52%), Gaps = 10/124 (8%) Frame = +1 Query: 151 VGTEEYIAPEIITGAG-------HTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANIL 309 VGT +Y++PEI+ G + DWWALG+ YEM YG TPF + T+ I+ Sbjct: 242 VGTPDYLSPEILQAVGGGPGTGSYGPECDWWALGVFAYEMFYGQTPFYADSTAETYGKIV 301 Query: 310 H--KDIRFP-ASISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINWALVRG 480 H + + P V AR I RLL P R+G G+ + + HPFF G++W +R Sbjct: 302 HYKEHLSLPLVDEGVPEEARDFIQRLL-CPPETRLGR-GGAGDFRTHPFFFGLDWDGLRD 359 Query: 481 TAPP 492 + PP Sbjct: 360 SVPP 363
>GRK6_RAT (P97711) G protein-coupled receptor kinase 6 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK6) Length = 576 Score = 80.1 bits (196), Expect = 6e-15 Identities = 44/108 (40%), Positives = 65/108 (60%), Gaps = 3/108 (2%) Frame = +1 Query: 151 VGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPF--RGKTRQRTFANILHKDIR 324 VGT Y+APE++ +T + DWWALG LLYEM+ G +PF R K +R L K++ Sbjct: 346 VGTVGYMAPEVVKNERYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVA 405 Query: 325 FPASISVSLPARQLIYRLLHRDPANRMGSY-EGSNEIKQHPFFRGINW 465 + S AR L +L ++DPA R+G G+ E+K+HP F+ +N+ Sbjct: 406 EEYTDRFSPQARSLCSQLPNKDPAERLGCRGGGAREVKEHPLFKKLNF 453
>LATS2_MOUSE (Q7TSJ6) Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Large| tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Kinase phosphorylated during mitosis protein) Length = 1042 Score = 79.3 bits (194), Expect = 1e-14 Identities = 40/112 (35%), Positives = 66/112 (58%), Gaps = 2/112 (1%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILH-- 312 ++S VGT YIAPE++ G+T DWW++G++L+EML G PF T T +++ Sbjct: 828 AHSLVGTPNYIAPEVLLRKGYTQLCDWWSVGVILFEMLVGQPPFLAPTPTETQLKVINWE 887 Query: 313 KDIRFPASISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINWA 468 + P + +S AR LI +L R+G +G++++K HPFF I+++ Sbjct: 888 STLHIPTQVRLSAEARDLITKLCCAADC-RLGR-DGADDLKAHPFFNTIDFS 937
>KSG1_SCHPO (Q12701) Serine/threonine-protein kinase ksg1 (EC 2.7.11.1)| Length = 592 Score = 79.3 bits (194), Expect = 1e-14 Identities = 48/123 (39%), Positives = 64/123 (52%) Frame = +1 Query: 124 EPMRASNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFAN 303 +P S SFVGT Y++PE+++ +A D WA G +L++ML G PF TF + Sbjct: 264 KPQAHSRSFVGTARYVSPEVLSDKIAGTASDIWAFGCILFQMLAGKPPFVAGNEYLTFQS 323 Query: 304 ILHKDIRFPASISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINWALVRGT 483 ILH P IS A LI +LL DP +R+ +EI QHPFF GI + Sbjct: 324 ILHLSYEIPPDISD--VASDLIKKLLVLDPKDRL----TVDEIHQHPFFNGIKFDNTLWE 377 Query: 484 APP 492 PP Sbjct: 378 LPP 380
>GRK4_RAT (P70507) G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK4) Length = 575 Score = 79.0 bits (193), Expect = 1e-14 Identities = 46/133 (34%), Positives = 77/133 (57%), Gaps = 8/133 (6%) Frame = +1 Query: 151 VGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFP 330 VGT Y+APEII+ +T + DWW LG L+YEM+ G++PFR K +++ + + ++ Sbjct: 346 VGTVGYMAPEIISHEKYTFSPDWWGLGCLIYEMIAGHSPFR-KYKEKVNREEMERRVKTE 404 Query: 331 A---SISVSLPARQLIYRLLHRDPANRMG-SYEGSNEIKQHPFFRGINWALVRGTA--PP 492 S S A+ + LL +DP+ R+G +G++ +KQHP F+ IN++ + PP Sbjct: 405 TEEYSERFSENAKSICSMLLTKDPSKRLGCQSDGASAVKQHPIFKDINFSRLEANMLDPP 464 Query: 493 KLDAP--LFSKDV 525 P ++ KD+ Sbjct: 465 FCPDPEAIYCKDI 477
>ARBK2_RAT (P26819) Beta-adrenergic receptor kinase 2 (EC 2.7.11.15)| (Beta-ARK-2) (G-protein-coupled receptor kinase 3) Length = 688 Score = 79.0 bits (193), Expect = 1e-14 Identities = 48/125 (38%), Positives = 75/125 (60%), Gaps = 11/125 (8%) Frame = +1 Query: 151 VGTEEYIAPEIIT-GAGHTSAVDWWALGILLYEMLYGYTPFR-GKTRQRTFANILHKDIR 324 VGT Y+APE++ G + S+ DW++LG +L+++L G++PFR KT+ + H+ R Sbjct: 351 VGTHGYMAPEVLQKGTCYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDK------HEIDR 404 Query: 325 FPASISVSLP------ARQLIYRLLHRDPANRMGSY-EGSNEIKQHPFFRGINWALV--R 477 +++V LP R L+ LL RD + R+G Y G+ E+K+H FF+GI+W V R Sbjct: 405 MTLTVNVQLPDAFSPELRSLLEGLLQRDVSQRLGCYGGGARELKEHIFFKGIDWQYVYLR 464 Query: 478 GTAPP 492 PP Sbjct: 465 KYPPP 469
>DMPK_MOUSE (P54265) Myotonin-protein kinase (EC 2.7.11.1) (Myotonic dystrophy| protein kinase) (MDPK) (DM-kinase) (DMK) (DMPK) (MT-PK) Length = 631 Score = 79.0 bits (193), Expect = 1e-14 Identities = 46/124 (37%), Positives = 66/124 (53%), Gaps = 10/124 (8%) Frame = +1 Query: 151 VGTEEYIAPEIITGAG-------HTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANIL 309 VGT +Y++PEI+ G + DWWALG+ YEM YG TPF + T+A I+ Sbjct: 232 VGTPDYLSPEILQAVGGGPGAGSYGPECDWWALGVFAYEMFYGQTPFYADSTAETYAKIV 291 Query: 310 H--KDIRFP-ASISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINWALVRG 480 H + + P A V A+ LI LL PA G+ + ++HPFF G++W +R Sbjct: 292 HYREHLSLPLADTVVPEEAQDLIRGLL--CPAEIRLGRGGAGDFQKHPFFFGLDWEGLRD 349 Query: 481 TAPP 492 + PP Sbjct: 350 SVPP 353
>KAPC_ENCCU (Q8SRK8) Probable cAMP-dependent protein kinase catalytic subunit| (EC 2.7.11.11) Length = 322 Score = 78.6 bits (192), Expect = 2e-14 Identities = 54/139 (38%), Positives = 73/139 (52%), Gaps = 8/139 (5%) Frame = +1 Query: 154 GTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPA 333 GT EY++PE + A D+W LG+++YEML G PF + + IL ++ FP Sbjct: 166 GTPEYMSPEKLRSEDDGRASDYWGLGVMIYEMLCGDPPFYDSSADAIYHKILESNVVFPH 225 Query: 334 SISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINWALV--RGTAPPKLDAP 507 VS AR LI LL ++ A R+G+ +G EI HPFF+GI+W V R PP + P Sbjct: 226 --YVSPVARCLITGLLDKNRATRLGT-KGICEIMGHPFFKGIDWHEVESRRIEPPFIPNP 282 Query: 508 ------LFSKDVGKGMGDA 546 L S KG DA Sbjct: 283 NTVLSSLASSGELKGTDDA 301
>ARBK2_HUMAN (P35626) Beta-adrenergic receptor kinase 2 (EC 2.7.11.15)| (Beta-ARK-2) (G-protein-coupled receptor kinase 3) Length = 688 Score = 78.2 bits (191), Expect = 2e-14 Identities = 47/129 (36%), Positives = 76/129 (58%), Gaps = 10/129 (7%) Frame = +1 Query: 151 VGTEEYIAPEIIT-GAGHTSAVDWWALGILLYEMLYGYTPFR-GKTRQRTFANILHKDIR 324 VGT Y+APE++ G + S+ DW++LG +L+++L G++PFR KT+ + H+ R Sbjct: 351 VGTHGYMAPEVLQKGTAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDK------HEIDR 404 Query: 325 FPASISVSLP------ARQLIYRLLHRDPANRMGSY-EGSNEIKQHPFFRGINWALV-RG 480 +++V LP + L+ LL RD + R+G + GS E+K+H FF+G++W V Sbjct: 405 MTLTVNVELPDTFSPELKSLLEGLLQRDVSKRLGCHGGGSQEVKEHSFFKGVDWQHVYLQ 464 Query: 481 TAPPKLDAP 507 PP L P Sbjct: 465 KYPPPLIPP 473
>ROCK1_RAT (Q63644) Rho-associated protein kinase 1 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (p150 RhoA-binding kinase ROK beta) (Liver regeneration-related protein LRRG199) Length = 1369 Score = 78.2 bits (191), Expect = 2e-14 Identities = 55/157 (35%), Positives = 80/157 (50%), Gaps = 8/157 (5%) Frame = +1 Query: 124 EPMRASNSFVGTEEYIAPEIITGAG----HTSAVDWWALGILLYEMLYGYTPFRGKTRQR 291 E M ++ VGT +YI+PE++ G + DWW++G+ LYEML G TPF + Sbjct: 226 EGMVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVG 285 Query: 292 TFANIL-HKD-IRFPASISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINW 465 T++ I+ HK+ + FP +S A+ LI L D R+G G EIK+H FF+ W Sbjct: 286 TYSKIMNHKNSLTFPDDNDISKEAKNLICAFL-TDREVRLGR-NGVEEIKRHLFFKNDQW 343 Query: 466 A--LVRGTAPPKLDAPLFSKDVGKGMGDAAAADNGTD 570 A +R T P + P S D+ D D G + Sbjct: 344 AWETLRDTVAPVV--PDLSSDIDTSNFDDLEEDKGDE 378
>ROCK1_RABIT (O77819) Rho-associated protein kinase 1 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (cAMP-dependent protein kinase ROCK-I) (CePKA) (Corneal epithelial Rho-associated-Ser/Thr kinase 1) (HEB Length = 1354 Score = 78.2 bits (191), Expect = 2e-14 Identities = 55/157 (35%), Positives = 80/157 (50%), Gaps = 8/157 (5%) Frame = +1 Query: 124 EPMRASNSFVGTEEYIAPEIITGAG----HTSAVDWWALGILLYEMLYGYTPFRGKTRQR 291 E M ++ VGT +YI+PE++ G + DWW++G+ LYEML G TPF + Sbjct: 226 EGMVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVG 285 Query: 292 TFANIL-HKD-IRFPASISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINW 465 T++ I+ HK+ + FP +S A+ LI L D R+G G EIK+H FF+ W Sbjct: 286 TYSKIMNHKNSLTFPDDNDISKEAKNLICAFL-TDREVRLGR-NGVEEIKRHLFFKNDQW 343 Query: 466 A--LVRGTAPPKLDAPLFSKDVGKGMGDAAAADNGTD 570 A +R T P + P S D+ D D G + Sbjct: 344 AWETLRDTVAPVV--PDLSSDIDTSNFDDLEEDKGDE 378
>ROCK1_MOUSE (P70335) Rho-associated protein kinase 1 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) Length = 1354 Score = 78.2 bits (191), Expect = 2e-14 Identities = 55/157 (35%), Positives = 80/157 (50%), Gaps = 8/157 (5%) Frame = +1 Query: 124 EPMRASNSFVGTEEYIAPEIITGAG----HTSAVDWWALGILLYEMLYGYTPFRGKTRQR 291 E M ++ VGT +YI+PE++ G + DWW++G+ LYEML G TPF + Sbjct: 226 EGMVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVG 285 Query: 292 TFANIL-HKD-IRFPASISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINW 465 T++ I+ HK+ + FP +S A+ LI L D R+G G EIK+H FF+ W Sbjct: 286 TYSKIMNHKNSLTFPDDNDISKEAKNLICAFL-TDREVRLGR-NGVEEIKRHLFFKNDQW 343 Query: 466 A--LVRGTAPPKLDAPLFSKDVGKGMGDAAAADNGTD 570 A +R T P + P S D+ D D G + Sbjct: 344 AWETLRDTVAPVV--PDLSSDIDTSNFDDLEEDKGDE 378
>ROCK1_HUMAN (Q13464) Rho-associated protein kinase 1 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen) Length = 1354 Score = 78.2 bits (191), Expect = 2e-14 Identities = 55/157 (35%), Positives = 80/157 (50%), Gaps = 8/157 (5%) Frame = +1 Query: 124 EPMRASNSFVGTEEYIAPEIITGAG----HTSAVDWWALGILLYEMLYGYTPFRGKTRQR 291 E M ++ VGT +YI+PE++ G + DWW++G+ LYEML G TPF + Sbjct: 226 EGMVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVG 285 Query: 292 TFANIL-HKD-IRFPASISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINW 465 T++ I+ HK+ + FP +S A+ LI L D R+G G EIK+H FF+ W Sbjct: 286 TYSKIMNHKNSLTFPDDNDISKEAKNLICAFL-TDREVRLGR-NGVEEIKRHLFFKNDQW 343 Query: 466 A--LVRGTAPPKLDAPLFSKDVGKGMGDAAAADNGTD 570 A +R T P + P S D+ D D G + Sbjct: 344 AWETLRDTVAPVV--PDLSSDIDTSNFDDLEEDKGEE 378
>ARBK2_BOVIN (P26818) Beta-adrenergic receptor kinase 2 (EC 2.7.11.15)| (Beta-ARK-2) (G-protein-coupled receptor kinase 3) Length = 688 Score = 77.4 bits (189), Expect = 4e-14 Identities = 49/129 (37%), Positives = 75/129 (58%), Gaps = 10/129 (7%) Frame = +1 Query: 151 VGTEEYIAPEIIT-GAGHTSAVDWWALGILLYEMLYGYTPFR-GKTRQRTFANILHKDIR 324 VGT Y+APE++ G + S+ DW++LG +L+++L G++PFR KT+ + H+ R Sbjct: 351 VGTHGYMAPEVLQKGTAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDK------HEIDR 404 Query: 325 FPASISVSLP------ARQLIYRLLHRDPANRMGSYEGS-NEIKQHPFFRGINWALV-RG 480 +++V LP + L+ LL RD + R+G + GS E+K H FFRGI+W V Sbjct: 405 MTLTMNVELPDVFSPELKSLLEGLLQRDVSKRLGCHGGSAQELKTHDFFRGIDWQHVYLQ 464 Query: 481 TAPPKLDAP 507 PP L P Sbjct: 465 KYPPPLIPP 473
>GRK4_MOUSE (O70291) G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK4) Length = 574 Score = 77.0 bits (188), Expect = 5e-14 Identities = 45/125 (36%), Positives = 71/125 (56%), Gaps = 6/125 (4%) Frame = +1 Query: 151 VGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFP 330 VGT Y+APEII +T + DWW LG L+YEM+ G++PFR K +++ L + ++ Sbjct: 346 VGTVGYMAPEIINHEKYTFSPDWWGLGCLIYEMIAGHSPFR-KYKEKVNREELERRVKNE 404 Query: 331 A---SISVSLPARQLIYRLLHRDPANRMG-SYEGSNEIKQHPFFRGINWALVRGTA--PP 492 S S A+ + LL +DP+ R+G +G + +KQHP F+ IN++ + PP Sbjct: 405 TEEYSERFSEDAKSICSMLLIKDPSKRLGCQRDGVSAVKQHPIFKDINFSRLEANMLDPP 464 Query: 493 KLDAP 507 + P Sbjct: 465 FIPDP 469
>DBF20_YEAST (P32328) Serine/threonine-protein kinase DBF20 (EC 2.7.11.1)| Length = 564 Score = 77.0 bits (188), Expect = 5e-14 Identities = 44/124 (35%), Positives = 74/124 (59%), Gaps = 6/124 (4%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILH-- 312 +NS VG+ +Y+A E++ G + VD+W+LG +L+E L GYTPF G + T+ N+ + Sbjct: 364 ANSMVGSPDYMALEVLEGKKYDFTVDYWSLGCMLFESLVGYTPFSGSSTNETYENLRYWK 423 Query: 313 KDIRFPAS----ISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINWALVRG 480 K +R P + + S LI RL+ DP NR+ S+E ++++ +F IN+ +R Sbjct: 424 KTLRRPRTEDRRAAFSDRTWDLITRLI-ADPINRVRSFE---QVRKMSYFAEINFETLRT 479 Query: 481 TAPP 492 ++PP Sbjct: 480 SSPP 483
>ICL1_KLULA (Q6CWQ4) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 361 Score = 76.6 bits (187), Expect = 7e-14 Identities = 41/108 (37%), Positives = 64/108 (59%) Frame = +1 Query: 118 FAEPMRASNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTF 297 + E + + GT +Y++PE+I + + VD WALG+L YE+L G PF T++ T+ Sbjct: 247 YNEDGQKRKTLCGTIDYLSPELIKSREYNNKVDVWALGVLTYELLVGSPPFEEDTKEMTY 306 Query: 298 ANILHKDIRFPASISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQH 441 IL D++FP ++VS AR LI RLL +P+ R+ +E+K H Sbjct: 307 RRILRCDLKFP--LNVSPQARDLIVRLLQFEPSKRI----PLSEVKSH 348
>AURKC_HUMAN (Q9UQB9) Serine/threonine-protein kinase 13 (EC 2.7.11.1)| (Aurora/Ipl1/Eg2 protein 2) (Aurora/Ipl1-related kinase 3) (Aurora-C) Length = 309 Score = 76.6 bits (187), Expect = 7e-14 Identities = 38/93 (40%), Positives = 52/93 (55%) Frame = +1 Query: 127 PMRASNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANI 306 P + GT +Y+ PE+I G + VD W +G+L YE+L GY PF + T+ I Sbjct: 192 PSLRRKTMCGTLDYLPPEMIEGRTYDEKVDLWCIGVLCYELLVGYPPFESASHSETYRRI 251 Query: 307 LHKDIRFPASISVSLPARQLIYRLLHRDPANRM 405 L D+RFP +S+ L AR LI RLL P R+ Sbjct: 252 LKVDVRFP--LSMPLGARDLISRLLRYQPLERL 282
>ARBK1_RAT (P26817) Beta-adrenergic receptor kinase 1 (EC 2.7.11.15)| (Beta-ARK-1) (G-protein-coupled receptor kinase 2) Length = 689 Score = 76.3 bits (186), Expect = 9e-14 Identities = 48/129 (37%), Positives = 74/129 (57%), Gaps = 10/129 (7%) Frame = +1 Query: 151 VGTEEYIAPEIIT-GAGHTSAVDWWALGILLYEMLYGYTPFR-GKTRQRTFANILHKDIR 324 VGT Y+APE++ G + S+ DW++LG +L+++L G++PFR KT+ + H+ R Sbjct: 351 VGTHGYMAPEVLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDK------HEIDR 404 Query: 325 FPASISVSLP------ARQLIYRLLHRDPANRMGSY-EGSNEIKQHPFFRGINWALV-RG 480 +++V LP R L+ LL RD R+G G+ EIK+ PFFR ++W +V Sbjct: 405 MTLTMAVELPDSFSPELRSLLEGLLQRDVNRRLGCLGRGAQEIKESPFFRSLDWQMVFLQ 464 Query: 481 TAPPKLDAP 507 PP L P Sbjct: 465 KYPPPLIPP 473
>DBF2_YEAST (P22204) Cell cycle protein kinase DBF2 (EC 2.7.11.1)| Length = 572 Score = 75.9 bits (185), Expect = 1e-13 Identities = 43/124 (34%), Positives = 69/124 (55%), Gaps = 6/124 (4%) Frame = +1 Query: 139 SNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANI---- 306 +NS VG+ +Y+A E++ G + VD+W+LG +L+E L GYTPF G + T+ N+ Sbjct: 372 ANSMVGSPDYMALEVLEGKKYDFTVDYWSLGCMLFESLVGYTPFSGSSTNETYDNLRRWK 431 Query: 307 --LHKDIRFPASISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINWALVRG 480 L + + + S LI RL+ DP NR+ S+E +K+ +F IN++ +R Sbjct: 432 QTLRRPRQSDGRAAFSDRTWDLITRLI-ADPINRLRSFE---HVKRMSYFADINFSTLRS 487 Query: 481 TAPP 492 PP Sbjct: 488 MIPP 491
>ARBK1_MOUSE (Q99MK8) Beta-adrenergic receptor kinase 1 (EC 2.7.11.15)| (Beta-ARK-1) (G-protein-coupled receptor kinase 2) Length = 689 Score = 75.9 bits (185), Expect = 1e-13 Identities = 47/129 (36%), Positives = 74/129 (57%), Gaps = 10/129 (7%) Frame = +1 Query: 151 VGTEEYIAPEIIT-GAGHTSAVDWWALGILLYEMLYGYTPFR-GKTRQRTFANILHKDIR 324 VGT Y+APE++ G + S+ DW++LG +L+++L G++PFR KT+ + H+ R Sbjct: 351 VGTHGYMAPEVLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDK------HEIDR 404 Query: 325 FPASISVSLP------ARQLIYRLLHRDPANRMGSY-EGSNEIKQHPFFRGINWALV-RG 480 +++V LP R L+ LL RD R+G G+ E+K+ PFFR ++W +V Sbjct: 405 MTLTMAVELPDSFSPELRSLLEGLLQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQ 464 Query: 481 TAPPKLDAP 507 PP L P Sbjct: 465 KYPPPLIPP 473
>ARBK1_MESAU (Q64682) Beta-adrenergic receptor kinase 1 (EC 2.7.11.15)| (Beta-ARK-1) (G-protein-coupled receptor kinase 2) Length = 689 Score = 75.9 bits (185), Expect = 1e-13 Identities = 47/129 (36%), Positives = 74/129 (57%), Gaps = 10/129 (7%) Frame = +1 Query: 151 VGTEEYIAPEIIT-GAGHTSAVDWWALGILLYEMLYGYTPFR-GKTRQRTFANILHKDIR 324 VGT Y+APE++ G + S+ DW++LG +L+++L G++PFR KT+ + H+ R Sbjct: 351 VGTHGYMAPEVLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDK------HEIDR 404 Query: 325 FPASISVSLP------ARQLIYRLLHRDPANRMGSY-EGSNEIKQHPFFRGINWALV-RG 480 +++V LP R L+ LL RD R+G G+ E+K+ PFFR ++W +V Sbjct: 405 MTLTMAVELPDSFSPELRSLLEGLLQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQ 464 Query: 481 TAPPKLDAP 507 PP L P Sbjct: 465 KYPPPLIPP 473
>ARBK1_BOVIN (P21146) Beta-adrenergic receptor kinase 1 (EC 2.7.11.15)| (Beta-ARK-1) (G-protein-coupled receptor kinase 2) Length = 689 Score = 75.9 bits (185), Expect = 1e-13 Identities = 47/129 (36%), Positives = 74/129 (57%), Gaps = 10/129 (7%) Frame = +1 Query: 151 VGTEEYIAPEIIT-GAGHTSAVDWWALGILLYEMLYGYTPFR-GKTRQRTFANILHKDIR 324 VGT Y+APE++ G + S+ DW++LG +L+++L G++PFR KT+ + H+ R Sbjct: 351 VGTHGYMAPEVLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDK------HEIDR 404 Query: 325 FPASISVSLP------ARQLIYRLLHRDPANRMGSY-EGSNEIKQHPFFRGINWALV-RG 480 +++V LP R L+ LL RD R+G G+ E+K+ PFFR ++W +V Sbjct: 405 MTLTMAVELPDSFSPELRSLLEGLLQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQ 464 Query: 481 TAPPKLDAP 507 PP L P Sbjct: 465 KYPPPLIPP 473
>GPRK1_DROME (P32865) G protein-coupled receptor kinase 1 (EC 2.7.11.16)| Length = 700 Score = 75.5 bits (184), Expect = 1e-13 Identities = 40/108 (37%), Positives = 65/108 (60%), Gaps = 3/108 (2%) Frame = +1 Query: 151 VGTEEYIAPEIIT-GAGHTSAVDWWALGILLYEMLYGYTPFR-GKTRQRTFANILHKDIR 324 VGT Y+APE+++ G + S DW++ G +LY++L G++PFR KT+ + + + + Sbjct: 352 VGTHGYMAPEVLSKGTSYDSCADWFSFGCMLYKLLKGHSPFRQHKTKDKLEIDKMTLTMN 411 Query: 325 FPASISVSLPARQLIYRLLHRDPANRMGSY-EGSNEIKQHPFFRGINW 465 S SL + L+ LL RD + R+G G++E+K H FF GI+W Sbjct: 412 VELPESFSLELKNLLEMLLQRDVSKRLGCMGNGADEVKMHNFFCGIDW 459
>IPL1_ASHGO (Q755C4) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 367 Score = 74.7 bits (182), Expect = 3e-13 Identities = 38/98 (38%), Positives = 59/98 (60%) Frame = +1 Query: 154 GTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPA 333 GT +Y++PE+I + VD WALG+L YE+L G PF ++++ T+ IL +++ FP Sbjct: 268 GTVDYLSPELIRSREYNEKVDVWALGVLTYELLVGSPPFEEESKELTYKRILKRNLIFPD 327 Query: 334 SISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPF 447 + AR LI RLL DP +R+ E+K+HP+ Sbjct: 328 HVDTE--ARHLISRLLEYDPGDRI----PLKEVKKHPW 359
>ARBK1_HUMAN (P25098) Beta-adrenergic receptor kinase 1 (EC 2.7.11.15)| (Beta-ARK-1) (G-protein coupled receptor kinase 2) Length = 689 Score = 73.9 bits (180), Expect = 4e-13 Identities = 46/129 (35%), Positives = 73/129 (56%), Gaps = 10/129 (7%) Frame = +1 Query: 151 VGTEEYIAPEIIT-GAGHTSAVDWWALGILLYEMLYGYTPFR-GKTRQRTFANILHKDIR 324 VGT Y+APE++ G + S+ DW++LG +L+++L G++PFR KT+ + H+ R Sbjct: 351 VGTHGYMAPEVLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDK------HEIDR 404 Query: 325 FPASISVSLP------ARQLIYRLLHRDPANRMGSY-EGSNEIKQHPFFRGINWALV-RG 480 +++V LP L+ LL RD R+G G+ E+K+ PFFR ++W +V Sbjct: 405 MTLTMAVELPDSFSPELHSLLEGLLQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQ 464 Query: 481 TAPPKLDAP 507 PP L P Sbjct: 465 RYPPPLIPP 473
>AURKB_HUMAN (Q96GD4) Serine/threonine-protein kinase 12 (EC 2.7.11.1) (Aurora-| and Ipl1-like midbody-associated protein 1) (AIM-1) (Aurora/IPL1-related kinase 2) (Aurora-related kinase 2) (STK-1) (Aurora-B) Length = 344 Score = 73.9 bits (180), Expect = 4e-13 Identities = 37/109 (33%), Positives = 58/109 (53%) Frame = +1 Query: 127 PMRASNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANI 306 P + GT +Y+ PE+I G H VD W +G+L YE+L G PF + T+ I Sbjct: 226 PSLRRKTMCGTLDYLPPEMIEGRMHNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRI 285 Query: 307 LHKDIRFPASISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFR 453 + D++FPAS+ A+ LI +LL +P+ R+ ++ HP+ R Sbjct: 286 VKVDLKFPASVPTG--AQDLISKLLRHNPSERL----PLAQVSAHPWVR 328
>GRK5_MOUSE (Q8VEB1) G protein-coupled receptor kinase 5 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK5) Length = 590 Score = 73.9 bits (180), Expect = 4e-13 Identities = 45/134 (33%), Positives = 73/134 (54%), Gaps = 9/134 (6%) Frame = +1 Query: 151 VGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGK----TRQRTFANILHKD 318 VGT Y+APE++ + + D+W LG L+YEM+ G +PFRG+ R+ +L + Sbjct: 346 VGTVGYMAPEVLNNQRYGLSPDYWGLGCLIYEMIEGQSPFRGRKEKVKREEVDRRVLETE 405 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMG-SYEGSNEIKQHPFFRGINWALVRG--TAP 489 + + S A+ + LL +D R+G EG+ E+K+HPFFR +N+ + P Sbjct: 406 EVYSSKFSEE--AKSICNMLLTKDSKQRLGCQEEGAAEVKRHPFFRNMNFKRLEAGMLDP 463 Query: 490 PKLDAP--LFSKDV 525 P + P ++ KDV Sbjct: 464 PFVPDPRAVYCKDV 477
>CTRO_HUMAN (O14578) Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK)| (Rho-interacting, serine/threonine-protein kinase 21) Length = 2027 Score = 73.9 bits (180), Expect = 4e-13 Identities = 45/122 (36%), Positives = 67/122 (54%), Gaps = 8/122 (6%) Frame = +1 Query: 151 VGTEEYIAPEIIT-----GAG-HTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILH 312 +GT +Y+APE++T G G + DWW++G++ YEM+YG +PF T RTF NI++ Sbjct: 258 IGTPDYMAPEVLTVMNGDGKGTYGLDCDWWSVGVIAYEMIYGRSPFAEGTSARTFNNIMN 317 Query: 313 --KDIRFPASISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRGINWALVRGTA 486 + ++FP VS LI LL +EG + HPFF I+W +R + Sbjct: 318 FQRFLKFPDDPKVSSDFLDLIQSLLCGQKERL--KFEG---LCCHPFFSKIDWNNIRNSP 372 Query: 487 PP 492 PP Sbjct: 373 PP 374
>GRK1_CAEBR (Q622Z7) G protein-coupled receptor kinase 1 (EC 2.7.11.16)| Length = 640 Score = 73.6 bits (179), Expect = 6e-13 Identities = 46/124 (37%), Positives = 64/124 (51%), Gaps = 9/124 (7%) Frame = +1 Query: 151 VGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFR---GKTRQRTFANILHKDI 321 VGT Y+APEI+ +T VDWW +G L+YEM+ G PFR K ++ + +D Sbjct: 362 VGTVGYMAPEIVKNERYTYGVDWWGVGCLIYEMIEGKAPFRQRKEKVKREEVERRVRED- 420 Query: 322 RFPASISVSLPARQLIYRLLHRDPANRMG------SYEGSNEIKQHPFFRGINWALVRGT 483 + S S AR L LLH++P R+G +G+ EI+ HPFF + A R Sbjct: 421 QEKYSEKFSEAARTLCRGLLHKEPGFRLGCRRVGKPEDGAEEIRAHPFFNTADTATGREP 480 Query: 484 APPK 495 P K Sbjct: 481 VPWK 484
>ROCK2_RAT (Q62868) Rho-associated protein kinase 2 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 2) (p164 ROCK-2) (RhoA-binding kinase 2) (p150 ROK-alpha) (ROKalpha) Length = 1379 Score = 73.2 bits (178), Expect = 7e-13 Identities = 52/146 (35%), Positives = 74/146 (50%), Gaps = 8/146 (5%) Frame = +1 Query: 151 VGTEEYIAPEIITGAG----HTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANIL-HK 315 VGT +YI+PE++ G + DWW++G+ L+EML G TPF + T++ I+ HK Sbjct: 242 VGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLFEMLVGDTPFYADSLVGTYSKIMDHK 301 Query: 316 D-IRFPASISVSLPARQLIYRLLHRDPANRMGSYEGSNEIKQHPFFRG--INWALVRGTA 486 + + FP +S A+ LI L D R+G G EIK FF+ NW +R TA Sbjct: 302 NSLCFPEDTEISKHAKNLICAFL-TDREVRLGR-NGVEEIKSASFFKNDQWNWDNIRETA 359 Query: 487 PPKLDAPLFSKDVGKGMGDAAAADNG 564 P + P S D+ D D G Sbjct: 360 APVV--PELSSDIDSSNFDDIEDDKG 383
>GRK5_RAT (Q62833) G protein-coupled receptor kinase 5 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK5) Length = 590 Score = 73.2 bits (178), Expect = 7e-13 Identities = 46/134 (34%), Positives = 73/134 (54%), Gaps = 9/134 (6%) Frame = +1 Query: 151 VGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGK----TRQRTFANILHKD 318 VGT Y+APE++ + + D+W LG L+YEM+ G +PFRG+ R+ +L + Sbjct: 346 VGTVGYMAPEVLNNQRYGLSPDYWGLGCLIYEMIEGQSPFRGRKEKVKREEVDRRVLETE 405 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMG-SYEGSNEIKQHPFFRGINWALVRG--TAP 489 + S S A+ + LL +D R+G EG+ E+K+HPFFR +N+ + P Sbjct: 406 EVY--SPKFSEEAKSICNMLLTKDSKQRLGCQEEGAAEVKRHPFFRNMNFKRLEAGMLDP 463 Query: 490 PKLDAP--LFSKDV 525 P + P ++ KDV Sbjct: 464 PFVPDPRAVYCKDV 477
>GRK5_HUMAN (P34947) G protein-coupled receptor kinase 5 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK5) Length = 590 Score = 73.2 bits (178), Expect = 7e-13 Identities = 46/134 (34%), Positives = 73/134 (54%), Gaps = 9/134 (6%) Frame = +1 Query: 151 VGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGK----TRQRTFANILHKD 318 VGT Y+APE++ + + D+W LG L+YEM+ G +PFRG+ R+ +L + Sbjct: 346 VGTVGYMAPEVLNNQRYGLSPDYWGLGCLIYEMIEGQSPFRGRKEKVKREEVDRRVLETE 405 Query: 319 IRFPASISVSLPARQLIYRLLHRDPANRMG-SYEGSNEIKQHPFFRGINWALVRG--TAP 489 + S S A+ + LL +D R+G EG+ E+K+HPFFR +N+ + P Sbjct: 406 EVY--SHKFSEEAKSICKMLLTKDAKQRLGCQEEGAAEVKRHPFFRNMNFKRLEAGMLDP 463 Query: 490 PKLDAP--LFSKDV 525 P + P ++ KDV Sbjct: 464 PFVPDPRAVYCKDV 477 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 106,386,189 Number of Sequences: 219361 Number of extensions: 2385594 Number of successful extensions: 8439 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 7436 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 7897 length of database: 80,573,946 effective HSP length: 109 effective length of database: 56,663,597 effective search space used: 7026286028 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
