ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | basd22j12 |
|---|---|
| Clone Library Name | barley_pub |
>FKB12_VICFA (O04287) Peptidyl-prolyl isomerase FKBP12 (EC 5.2.1.8) (12 kDa| FK506-binding protein) (12 kDa FKBP) (FKBP-12) (Immunophilin FKBP12) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) Length = 112 Score = 196 bits (497), Expect = 5e-50 Identities = 88/112 (78%), Positives = 100/112 (89%) Frame = +3 Query: 57 MGIQKEILRAGTGPKPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVI 236 MG++K+I+RAGTGP P +GQ VTVHCTGYGK+GDLS+KFWSTKDPGQ PF F IG GSVI Sbjct: 1 MGVEKQIIRAGTGPNPSRGQNVTVHCTGYGKNGDLSQKFWSTKDPGQNPFTFKIGQGSVI 60 Query: 237 KGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVLSAK 392 KGWDEGV+ MQLGEVARL+C+PDYAYG+GG PAWGIQPNS L FEIEVL A+ Sbjct: 61 KGWDEGVLGMQLGEVARLRCSPDYAYGAGGFPAWGIQPNSVLEFEIEVLRAQ 112
>FKB12_ARATH (Q8LGG0) Peptidyl-prolyl isomerase FKBP12 (EC 5.2.1.8) (12 kDa| FK506-binding protein) (12 kDa FKBP) (FKBP-12) (Immunophilin FKBP12) (AtFKBP12) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) Length = 112 Score = 186 bits (471), Expect = 5e-47 Identities = 82/112 (73%), Positives = 98/112 (87%) Frame = +3 Query: 57 MGIQKEILRAGTGPKPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVI 236 MG++K+++R G GPKP GQ VTVHCTG+GKDGDLS+KFWSTKD GQ+PF+F IG G+VI Sbjct: 1 MGVEKQVIRPGNGPKPAPGQTVTVHCTGFGKDGDLSQKFWSTKDEGQKPFSFQIGKGAVI 60 Query: 237 KGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVLSAK 392 KGWDEGV+ MQ+GEVARL+C+ DYAYG+GG PAWGIQPNS L FEIEVLS + Sbjct: 61 KGWDEGVIGMQIGEVARLRCSSDYAYGAGGFPAWGIQPNSVLDFEIEVLSVQ 112
>FKBP_ASPOR (Q2U316) FK506-binding protein 1 (EC 5.2.1.8) (FKBP)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rapamycin-binding protein) Length = 116 Score = 107 bits (268), Expect = 2e-23 Identities = 56/115 (48%), Positives = 72/115 (62%), Gaps = 6/115 (5%) Frame = +3 Query: 57 MGIQKEILRAGTGPKPVKGQKVTVHCTGYGKD------GDLSKKFWSTKDPGQQPFAFNI 218 MG++++I+ G+GP P G KV++H TG+ D G K+F S++ PG+ P NI Sbjct: 1 MGVERKIITRGSGPSPASGDKVSIHYTGWIYDPKKANKGFQGKQFDSSRSPGRGPLVVNI 60 Query: 219 GLGSVIKGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVL 383 G G VIKGWDEGVM M LGE + L TPDY YG A I NS LIFE+E+L Sbjct: 61 GQGKVIKGWDEGVMQMSLGEKSTLTITPDYGYGD--KAAGKIPANSTLIFEVELL 113
>FKBP_GIBZE (Q4HZB8) FK506-binding protein 1 (EC 5.2.1.8) (FKBP) (FkbA)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rapamycin-binding protein) Length = 111 Score = 102 bits (253), Expect = 9e-22 Identities = 53/108 (49%), Positives = 68/108 (62%) Frame = +3 Query: 57 MGIQKEILRAGTGPKPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVI 236 MG++K I+ G+GP P GQKVT+ TG+ + D +K G+ F NIG+G VI Sbjct: 1 MGVEKTIITQGSGPSPQVGQKVTMEYTGWLQKEDGTKGDQFDTSVGRGDFVVNIGVGQVI 60 Query: 237 KGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEV 380 KGWDEGV M+LGE A L +PDY YG G P I PNS LIF++E+ Sbjct: 61 KGWDEGVTQMKLGEKATLHISPDYGYGPRGFPG-AIPPNSTLIFDVEL 107
>FKB12_DROME (P48375) 12 kDa FK506-binding protein (EC 5.2.1.8) (FKBP)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (Macrolide-binding protein) Length = 108 Score = 97.4 bits (241), Expect = 2e-20 Identities = 56/113 (49%), Positives = 71/113 (62%), Gaps = 1/113 (0%) Frame = +3 Query: 57 MGIQKEILRAGTGPK-PVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSV 233 MG+Q + G G P GQKVTVH TG DG KF S++D + PF F IG G V Sbjct: 1 MGVQVVPIAPGDGSTYPKNGQKVTVHYTGTLDDGT---KFDSSRDRNK-PFKFTIGKGEV 56 Query: 234 IKGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVLSAK 392 I+GWDEGV + +G+ A+L C+PDYAYGS G P I PNS L F++E+L + Sbjct: 57 IRGWDEGVAQLSVGQRAKLICSPDYAYGSRGHPG-VIPPNSTLTFDVELLKVE 108
>FKBP_SCHPO (O42993) FK506-binding protein (FKBP) (Peptidyl-prolyl cis-trans| isomerase) (PPIase) (EC 5.2.1.8) Length = 112 Score = 97.1 bits (240), Expect = 3e-20 Identities = 54/113 (47%), Positives = 74/113 (65%), Gaps = 3/113 (2%) Frame = +3 Query: 57 MGIQKEILRAGTG---PKPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLG 227 MG++K+++ +G G PKP G ++T+H TG +G KKF S+ D G PF IG+G Sbjct: 1 MGVEKQVISSGNGQDFPKP--GDRITMHYTGTLTNG---KKFDSSVDRGS-PFVCTIGVG 54 Query: 228 SVIKGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVLS 386 +I+GWDEGV M LGE A+L TPDY YG G P I PNS L+F++E+L+ Sbjct: 55 QLIRGWDEGVPKMSLGEKAKLTITPDYGYGPRGFPGL-IPPNSTLLFDVELLA 106
>FKBP4_RABIT (P27124) FK506-binding protein 4 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) (p59 protein) (HSP-binding immunophilin) (HBI) (FKBP52 protein) (52 kDa FK506-binding protein) (FKBP59) Length = 457 Score = 91.3 bits (225), Expect = 2e-18 Identities = 52/112 (46%), Positives = 71/112 (63%), Gaps = 1/112 (0%) Frame = +3 Query: 60 GIQKEILRAGTGPK-PVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVI 236 G+ K I R GTG + P+ G +V VH TG+ DG KF S+ D + F+F++G G VI Sbjct: 31 GVLKVIKREGTGTETPMIGDRVFVHYTGWLLDGT---KFDSSLDR-KDKFSFDLGKGEVI 86 Query: 237 KGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVLSAK 392 K WD V M++GE+ R+ C P+YAYGS GSP I PN+ L+FE+E+ K Sbjct: 87 KAWDIAVATMKVGELCRITCKPEYAYGSAGSPP-KIPPNATLVFEVELFEFK 137 Score = 45.1 bits (105), Expect = 1e-04 Identities = 37/120 (30%), Positives = 54/120 (45%), Gaps = 4/120 (3%) Frame = +3 Query: 39 DAEDGKMGIQKEILRAGTG-PKPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFN 215 D EDG GI + I G G +P G V V GY KD Q+ F Sbjct: 143 DDEDG--GIIRRIRTRGEGYARPNDGAIVEVALEGYYKDRLFD----------QRELRFE 190 Query: 216 IGLGSVIK---GWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVLS 386 +G G + G ++ + M+ GE + L P YA+G+ G + I P +EL +E+ + S Sbjct: 191 VGEGESLDLPCGLEKAIQRMEKGEHSILYLKPSYAFGNAGKEKFQIPPYAELKYEVHLKS 250
>FKBP_CRYNE (Q5KMG3) FK506-binding protein 1 (EC 5.2.1.8) (FKBP)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rapamycin-binding protein) Length = 108 Score = 91.3 bits (225), Expect = 2e-18 Identities = 54/110 (49%), Positives = 66/110 (60%), Gaps = 1/110 (0%) Frame = +3 Query: 57 MGIQKEILRAGTGPK-PVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSV 233 MG+ E + AG G P G VT+H G DG KF S++D G PF IG G V Sbjct: 1 MGVTVENISAGDGKTFPQPGDSVTIHYVGTLLDGS---KFDSSRDRGT-PFVCRIGQGQV 56 Query: 234 IKGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVL 383 I+GWDEGV + +G+ A L CTPDYAYG+ G P I PNS L FE+E+L Sbjct: 57 IRGWDEGVPQLSIGQKANLICTPDYAYGARGFPP-VIPPNSTLKFEVELL 105
>FKBP_CRYNV (O94746) FK506-binding protein 1 (EC 5.2.1.8) (FKBP)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rapamycin-binding protein) Length = 108 Score = 90.9 bits (224), Expect = 2e-18 Identities = 54/110 (49%), Positives = 66/110 (60%), Gaps = 1/110 (0%) Frame = +3 Query: 57 MGIQKEILRAGTGPK-PVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSV 233 MG+ E + AG G P G VT+H G DG KF S++D G PF IG G V Sbjct: 1 MGVTVENISAGDGKTFPQPGDNVTIHYVGTLLDGS---KFDSSRDRGT-PFVCRIGQGQV 56 Query: 234 IKGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVL 383 I+GWDEGV + +G+ A L CTPDYAYG+ G P I PNS L FE+E+L Sbjct: 57 IRGWDEGVPQLSVGQKANLICTPDYAYGARGFPP-VIPPNSTLKFEVELL 105
>FKB1A_EMENI (Q6KBA8) FK506-binding protein 1A (EC 5.2.1.8) (FKBP) (FkbA)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rapamycin-binding protein) Length = 108 Score = 90.9 bits (224), Expect = 2e-18 Identities = 55/113 (48%), Positives = 72/113 (63%), Gaps = 4/113 (3%) Frame = +3 Query: 57 MGIQKEILRAGTG---PKPVKGQKVTVHCTGYGKDGDLSKKFWSTKD-PGQQPFAFNIGL 224 MG++ + + G G PKP G V++H TG DG KF S++D PG F IG+ Sbjct: 1 MGVEVQRISPGDGKNFPKP--GDTVSIHYTGTLADGS---KFDSSRDRPGT--FVTQIGV 53 Query: 225 GSVIKGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVL 383 G VIKGWDEGV+ + +GE A+L CTPDYAYG+ G P I PN+ L FE+E+L Sbjct: 54 GRVIKGWDEGVLQLSVGEKAKLICTPDYAYGARGFPP-VIPPNATLTFEVELL 105
>FKB1A_ASPFU (Q4WLV6) FK506-binding protein 1A (EC 5.2.1.8) (FKBP)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rapamycin-binding protein) Length = 112 Score = 90.5 bits (223), Expect = 3e-18 Identities = 57/110 (51%), Positives = 65/110 (59%), Gaps = 1/110 (0%) Frame = +3 Query: 57 MGIQKEILRAGTGPK-PVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSV 233 MG+ KE+ G G P KG VT+H TG DG KF S+ D + PF IG G V Sbjct: 1 MGVTKELKSPGNGVDFPKKGDFVTIHYTGRLTDGS---KFDSSVDRNE-PFQTQIGTGRV 56 Query: 234 IKGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVL 383 IKGWDEGV M LGE A L TPDY YG+ G P I NS LIFE+E+L Sbjct: 57 IKGWDEGVPQMSLGEKAVLTITPDYGYGARGFPP-VIPGNSTLIFEVELL 105
>FKBP4_HUMAN (Q02790) FK506-binding protein 4 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) (p59 protein) (HSP-binding immunophilin) (HBI) (FKBP52 protein) (52 kDa FK506-binding protein) (FKBP59) Length = 458 Score = 90.1 bits (222), Expect = 4e-18 Identities = 51/112 (45%), Positives = 70/112 (62%), Gaps = 1/112 (0%) Frame = +3 Query: 60 GIQKEILRAGTGPK-PVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVI 236 G+ K I R GTG + P+ G +V VH TG+ DG KF S+ D + F+F++G G VI Sbjct: 31 GVLKVIKREGTGTEMPMIGDRVFVHYTGWLLDGT---KFDSSLDR-KDKFSFDLGKGEVI 86 Query: 237 KGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVLSAK 392 K WD + M++GEV + C P+YAYGS GSP I PN+ L+FE+E+ K Sbjct: 87 KAWDIAIATMKVGEVCHITCKPEYAYGSAGSPP-KIPPNATLVFEVELFEFK 137 Score = 48.1 bits (113), Expect = 2e-05 Identities = 41/120 (34%), Positives = 57/120 (47%), Gaps = 4/120 (3%) Frame = +3 Query: 39 DAEDGKMGIQKEILRAGTG-PKPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFN 215 + EDG GI + I G G KP +G V V GY KD K F Q+ F Sbjct: 143 EEEDG--GIIRRIQTRGEGYAKPNEGAIVEVALEGYYKD----KLF------DQRELRFE 190 Query: 216 IGLGSVIK---GWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVLS 386 IG G + G + + M+ GE + + P YA+GS G + I PN+EL +E+ + S Sbjct: 191 IGEGENLDLPYGLERAIQRMEKGEHSIVYLKPSYAFGSVGKEKFQIPPNAELKYELHLKS 250
>FKBP4_MOUSE (P30416) FK506-binding protein 4 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) (p59 protein) (HSP-binding immunophilin) (HBI) (FKBP52 protein) (52 kDa FK506-binding protein) (FKBP59) Length = 457 Score = 89.4 bits (220), Expect = 6e-18 Identities = 51/112 (45%), Positives = 70/112 (62%), Gaps = 1/112 (0%) Frame = +3 Query: 60 GIQKEILRAGTGPK-PVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVI 236 G+ K I R GTG + P+ G +V VH TG+ DG KF S+ D + F+F++G G VI Sbjct: 31 GVLKVIKREGTGTETPMIGDRVFVHYTGWLLDGT---KFDSSLDR-KDKFSFDLGKGEVI 86 Query: 237 KGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVLSAK 392 K WD V M++GEV + C P+YAYG+ GSP I PN+ L+FE+E+ K Sbjct: 87 KAWDIAVATMKVGEVCHITCKPEYAYGAAGSPP-KIPPNATLVFEVELFEFK 137 Score = 47.0 bits (110), Expect = 4e-05 Identities = 37/120 (30%), Positives = 55/120 (45%), Gaps = 4/120 (3%) Frame = +3 Query: 39 DAEDGKMGIQKEILRAGTG-PKPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFN 215 + EDG GI + I G G +P G V V GY KD Q+ F Sbjct: 143 EEEDG--GIIRRIRTRGEGYARPNDGAMVEVALEGYHKDRLFD----------QRELCFE 190 Query: 216 IGLGSVIK---GWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVLS 386 +G G + G +E + M+ GE + + P YA+GS G + I P++EL +E+ + S Sbjct: 191 VGEGESLDLPCGLEEAIQRMEKGEHSIVYLKPSYAFGSVGKERFQIPPHAELRYEVRLKS 250
>FKB1A_XENLA (O42123) FK506-binding protein 1A (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) (12 kDa FKBP) (FKBP-12) (Immunophilin FKBP12) Length = 107 Score = 88.2 bits (217), Expect = 1e-17 Identities = 51/109 (46%), Positives = 69/109 (63%), Gaps = 1/109 (0%) Frame = +3 Query: 60 GIQKEILRAGTGPK-PVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVI 236 G+Q E + G G P KGQ V VH G ++G KKF S++D + PF F IG VI Sbjct: 1 GVQVETITEGDGRTFPKKGQTVVVHYVGSLENG---KKFDSSRDRNK-PFKFIIGRCEVI 56 Query: 237 KGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVL 383 +GW+EGV M +G+ ARL C+PD+AYG+ G P I PN+ L F++E+L Sbjct: 57 RGWEEGVAQMSVGQRARLTCSPDFAYGATGHPGI-IPPNATLTFDVELL 104
>FKB1A_BOVIN (P18203) FK506-binding protein 1A (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) (12 kDa FKBP) (FKBP-12) (Immunophilin FKBP12) Length = 107 Score = 87.4 bits (215), Expect = 2e-17 Identities = 50/109 (45%), Positives = 69/109 (63%), Gaps = 1/109 (0%) Frame = +3 Query: 60 GIQKEILRAGTGPK-PVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVI 236 G+Q E + G G P +GQ VH TG +DG KKF S++D + PF F +G VI Sbjct: 1 GVQVETISPGDGRTFPKRGQTCVVHYTGMLEDG---KKFDSSRDRNK-PFKFVLGKQEVI 56 Query: 237 KGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVL 383 +GW+EGV M +G+ A+L +PDYAYG+ G P I PN+ LIF++E+L Sbjct: 57 RGWEEGVAQMSVGQRAKLTISPDYAYGATGHPGI-IPPNATLIFDVELL 104
>FKB1B_MOUSE (Q9Z2I2) FK506-binding protein 1B (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase 1B) (PPIase 1B) (Rotamase 1B) (12.6 kDa FKBP) (FKBP-12.6) (Immunophilin FKBP12.6) Length = 107 Score = 87.0 bits (214), Expect = 3e-17 Identities = 52/110 (47%), Positives = 69/110 (62%), Gaps = 1/110 (0%) Frame = +3 Query: 60 GIQKEILRAGTGPK-PVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVI 236 G++ E + G G P KGQ VH TG ++G KKF S++D + PF F IG VI Sbjct: 1 GVEIETISPGDGRTFPKKGQICVVHYTGMLQNG---KKFDSSRDRNK-PFKFRIGKQEVI 56 Query: 237 KGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVLS 386 KG++EG M LG+ A+L CTPD AYG+ G P I PN+ LIF++E+LS Sbjct: 57 KGFEEGTAQMSLGQRAKLTCTPDVAYGATGHPG-VIPPNATLIFDVELLS 105
>FKBP5_MOUSE (Q64378) FK506-binding protein 5 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) (51 kDa FK506-binding protein) (FKBP-51) Length = 456 Score = 87.0 bits (214), Expect = 3e-17 Identities = 53/112 (47%), Positives = 67/112 (59%), Gaps = 1/112 (0%) Frame = +3 Query: 60 GIQKEILRAGTGPK-PVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVI 236 G+ K + R GT + P+ G KV VH G DG KKF S+ D ++PFAF++G G VI Sbjct: 32 GVLKIVKRVGTSDEAPMFGDKVYVHYKGMLSDG---KKFDSSHDR-KKPFAFSLGQGQVI 87 Query: 237 KGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVLSAK 392 K WD GV M+ GE+ L C P+YAYGS G I N+ L FEIE+L K Sbjct: 88 KAWDIGVSTMKKGEICHLLCKPEYAYGSAGH-LQKIPSNATLFFEIELLDFK 138 Score = 46.2 bits (108), Expect = 6e-05 Identities = 36/124 (29%), Positives = 57/124 (45%), Gaps = 4/124 (3%) Frame = +3 Query: 60 GIQKEILRAGTG-PKPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGS-- 230 G+ + I R G G P +G V VH +G + + +D F +G G Sbjct: 147 GVIRRIKRKGEGYSNPNEGATVKVHL-----EGCCGGRTFDCRD-----VVFVVGEGEDH 196 Query: 231 -VIKGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVLSAK*CAMR 407 + G D+ ++ MQ E L P Y +G G P +GI PN+EL++E+ + S + Sbjct: 197 DIPIGIDKALVKMQREEQCILYLGPRYGFGEAGKPKFGIDPNAELMYEVTLKSFEKAKES 256 Query: 408 FMMD 419 + MD Sbjct: 257 WEMD 260
>FKB1B_HUMAN (P68106) FK506-binding protein 1B (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase 1B) (PPIase 1B) (Rotamase 1B) (12.6 kDa FKBP) (FKBP-12.6) (Immunophilin FKBP12.6) (h-FKBP-12) Length = 107 Score = 86.7 bits (213), Expect = 4e-17 Identities = 51/110 (46%), Positives = 69/110 (62%), Gaps = 1/110 (0%) Frame = +3 Query: 60 GIQKEILRAGTGPK-PVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVI 236 G++ E + G G P KGQ VH TG ++G KKF S++D + PF F IG VI Sbjct: 1 GVEIETISPGDGRTFPKKGQTCVVHYTGMLQNG---KKFDSSRDRNK-PFKFRIGKQEVI 56 Query: 237 KGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVLS 386 KG++EG M LG+ A+L CTPD AYG+ G P I PN+ LIF++E+L+ Sbjct: 57 KGFEEGAAQMSLGQRAKLTCTPDVAYGATGHPG-VIPPNATLIFDVELLN 105
>FKB1B_BOVIN (P68107) FK506-binding protein 1B (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase 1B) (PPIase 1B) (Rotamase 1B) (12.6 kDa FKBP) (FKBP-12.6) (Immunophilin FKBP12.6) Length = 107 Score = 86.7 bits (213), Expect = 4e-17 Identities = 51/110 (46%), Positives = 69/110 (62%), Gaps = 1/110 (0%) Frame = +3 Query: 60 GIQKEILRAGTGPK-PVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVI 236 G++ E + G G P KGQ VH TG ++G KKF S++D + PF F IG VI Sbjct: 1 GVEIETISPGDGRTFPKKGQTCVVHYTGMLQNG---KKFDSSRDRNK-PFKFRIGKQEVI 56 Query: 237 KGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVLS 386 KG++EG M LG+ A+L CTPD AYG+ G P I PN+ LIF++E+L+ Sbjct: 57 KGFEEGAAQMSLGQRAKLTCTPDVAYGATGHPG-VIPPNATLIFDVELLN 105
>FKB1A_RAT (Q62658) FK506-binding protein 1A (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) (12 kDa FKBP) (FKBP-12) (Immunophilin FKBP12) Length = 107 Score = 86.3 bits (212), Expect = 5e-17 Identities = 48/109 (44%), Positives = 70/109 (64%), Gaps = 1/109 (0%) Frame = +3 Query: 60 GIQKEILRAGTGPK-PVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVI 236 G+Q E + +G G P +GQ VH TG +DG KKF S++D + PF F +G VI Sbjct: 1 GVQVETISSGDGRTFPKRGQTCVVHYTGMLEDG---KKFDSSRDRNK-PFKFTLGKQEVI 56 Query: 237 KGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVL 383 +GW+EGV M +G+ A+L +PDYAYG+ G P I P++ L+F++E+L Sbjct: 57 RGWEEGVAQMSVGQRAKLIISPDYAYGATGHPGI-IPPHATLVFDVELL 104
>FKB1B_RAT (P97534) FK506-binding protein 1B (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase 1B) (PPIase 1B) (Rotamase 1B) (12.6 kDa FKBP) (FKBP-12.6) (Immunophilin FKBP12.6) Length = 107 Score = 85.9 bits (211), Expect = 7e-17 Identities = 51/110 (46%), Positives = 69/110 (62%), Gaps = 1/110 (0%) Frame = +3 Query: 60 GIQKEILRAGTGPK-PVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVI 236 G++ E + G G P KGQ VH TG ++G KKF S++D + PF F IG VI Sbjct: 1 GVEIETISPGDGRTFPKKGQICVVHYTGMLQNG---KKFDSSRDRNK-PFKFRIGKQEVI 56 Query: 237 KGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVLS 386 KG++EG M LG+ A+L CTPD AYG+ G P I PN+ LIF++E+L+ Sbjct: 57 KGFEEGAAQMSLGQRAKLTCTPDVAYGATGHPG-VIPPNATLIFDVELLN 105
>FKB59_DROME (Q9VL78) FK506-binding protein 59 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) (dFKBP59) Length = 439 Score = 85.9 bits (211), Expect = 7e-17 Identities = 52/115 (45%), Positives = 69/115 (60%), Gaps = 1/115 (0%) Frame = +3 Query: 51 GKMGIQKEILRAGTGPK-PVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLG 227 G G+ KEIL+ GTG + P G V++H TG DG S +P F F++G G Sbjct: 11 GDGGVLKEILKEGTGTETPHSGCTVSLHYTGRLVDGTEFDSSLSRNEP----FEFSLGKG 66 Query: 228 SVIKGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVLSAK 392 +VIK +D GV M+LGE L C P+YAYG+ GSP I P++ LIFE+E+L K Sbjct: 67 NVIKAFDMGVATMKLGERCFLTCAPNYAYGAAGSPP-AIPPDATLIFELEMLGWK 120 Score = 36.2 bits (82), Expect = 0.063 Identities = 31/126 (24%), Positives = 58/126 (46%), Gaps = 8/126 (6%) Frame = +3 Query: 30 WRGDA----EDGKMGIQKEILRAGTGPK-PVKGQKVTVHCTGYGKDGDLSKKFWSTKDPG 194 W+G+ +DG I + IL A + P G V H +G + + +D Sbjct: 119 WKGEDLSPNQDGS--IDRTILEASDKKRTPSDGAFVKAHISG-----SFEGRVFEDRD-- 169 Query: 195 QQPFAFNIGLGS---VIKGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELI 365 F+ G G +I G + + M +GE +R+K YA+G+ G+ + I PN+ + Sbjct: 170 ---VEFDYGEGKAIGIIDGVEIALEKMNVGETSRIKIQAKYAFGAKGNEEFKIPPNATVE 226 Query: 366 FEIEVL 383 + ++++ Sbjct: 227 YTVKLV 232
>FKB1A_RABIT (P62943) FK506-binding protein 1A (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) (12 kDa FKBP) (FKBP-12) (Immunophilin FKBP12) Length = 107 Score = 85.5 bits (210), Expect = 9e-17 Identities = 48/109 (44%), Positives = 69/109 (63%), Gaps = 1/109 (0%) Frame = +3 Query: 60 GIQKEILRAGTGPK-PVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVI 236 G+Q E + G G P +GQ VH TG +DG KKF S++D + PF F +G VI Sbjct: 1 GVQVETISPGDGRTFPKRGQTCVVHYTGMLEDG---KKFDSSRDRNK-PFKFMLGKQEVI 56 Query: 237 KGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVL 383 +GW+EGV M +G+ A+L +PDYAYG+ G P I P++ L+F++E+L Sbjct: 57 RGWEEGVAQMSVGQRAKLTISPDYAYGATGHPGI-IPPHATLVFDVELL 104
>FKB1A_HUMAN (P62942) FK506-binding protein 1A (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) (12 kDa FKBP) (FKBP-12) (Immunophilin FKBP12) Length = 107 Score = 85.5 bits (210), Expect = 9e-17 Identities = 48/109 (44%), Positives = 69/109 (63%), Gaps = 1/109 (0%) Frame = +3 Query: 60 GIQKEILRAGTGPK-PVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVI 236 G+Q E + G G P +GQ VH TG +DG KKF S++D + PF F +G VI Sbjct: 1 GVQVETISPGDGRTFPKRGQTCVVHYTGMLEDG---KKFDSSRDRNK-PFKFMLGKQEVI 56 Query: 237 KGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVL 383 +GW+EGV M +G+ A+L +PDYAYG+ G P I P++ L+F++E+L Sbjct: 57 RGWEEGVAQMSVGQRAKLTISPDYAYGATGHPGI-IPPHATLVFDVELL 104
>FKB1B_RABIT (Q8HYX6) FK506-binding protein 1B (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase 1B) (PPIase 1B) (Rotamase 1B) (12.6 kDa FKBP) (FKBP-12.6) (Immunophilin FKBP12.6) Length = 107 Score = 85.1 bits (209), Expect = 1e-16 Identities = 51/110 (46%), Positives = 68/110 (61%), Gaps = 1/110 (0%) Frame = +3 Query: 60 GIQKEILRAGTGPK-PVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVI 236 G++ E + G G P KGQ VH TG ++G KKF S++D + PF F IG VI Sbjct: 1 GVEIETISPGDGRTFPKKGQTCVVHYTGMLQNG---KKFDSSRDRNK-PFKFRIGKQEVI 56 Query: 237 KGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVLS 386 KG++EG M LG+ A+L CTPD AYG+ G P I PN+ LIF +E+L+ Sbjct: 57 KGFEEGAAQMSLGQRAKLTCTPDVAYGATGHPG-VIPPNATLIFGVELLN 105
>FKBP5_PONPY (Q5RF88) FK506-binding protein 5 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) Length = 457 Score = 85.1 bits (209), Expect = 1e-16 Identities = 52/112 (46%), Positives = 66/112 (58%), Gaps = 1/112 (0%) Frame = +3 Query: 60 GIQKEILRAGTGPK-PVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVI 236 G+ K + R G G + P+ G KV VH G +G KKF S+ D + PF F++G G VI Sbjct: 32 GVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNG---KKFDSSHDRNE-PFVFSLGKGQVI 87 Query: 237 KGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVLSAK 392 K WD GV M+ GE+ L C P+YAYGS GS I N+ L FEIE+L K Sbjct: 88 KAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP-KIPSNATLFFEIELLDFK 138 Score = 50.4 bits (119), Expect = 3e-06 Identities = 40/129 (31%), Positives = 60/129 (46%), Gaps = 4/129 (3%) Frame = +3 Query: 45 EDGKMGIQKEILRAGTG-PKPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIG 221 EDG GI + R G G P +G V +H +G + + +D AF +G Sbjct: 144 EDG--GIIRRTKRKGEGYSNPNEGATVEIHL-----EGRCGGRMFDCRD-----VAFTVG 191 Query: 222 LGS---VIKGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVLSAK 392 G + G D+ + MQ E L P Y +G G P +GI+PN+ELI+E+ + S + Sbjct: 192 EGEDHVIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFE 251 Query: 393 *CAMRFMMD 419 + MD Sbjct: 252 KAKESWEMD 260
>FKBP5_HUMAN (Q13451) FK506-binding protein 5 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) (51 kDa FK506-binding protein) (FKBP-51) (54 kDa progesterone receptor-associated immunophilin) (FKBP54) (P54) (FF1 antigen) (HSP90-bindin Length = 457 Score = 85.1 bits (209), Expect = 1e-16 Identities = 52/112 (46%), Positives = 66/112 (58%), Gaps = 1/112 (0%) Frame = +3 Query: 60 GIQKEILRAGTGPK-PVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVI 236 G+ K + R G G + P+ G KV VH G +G KKF S+ D + PF F++G G VI Sbjct: 32 GVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNG---KKFDSSHDRNE-PFVFSLGKGQVI 87 Query: 237 KGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVLSAK 392 K WD GV M+ GE+ L C P+YAYGS GS I N+ L FEIE+L K Sbjct: 88 KAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP-KIPSNATLFFEIELLDFK 138 Score = 50.4 bits (119), Expect = 3e-06 Identities = 40/129 (31%), Positives = 60/129 (46%), Gaps = 4/129 (3%) Frame = +3 Query: 45 EDGKMGIQKEILRAGTG-PKPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIG 221 EDG GI + R G G P +G V +H +G + + +D AF +G Sbjct: 144 EDG--GIIRRTKRKGEGYSNPNEGATVEIHL-----EGRCGGRMFDCRD-----VAFTVG 191 Query: 222 LGS---VIKGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVLSAK 392 G + G D+ + MQ E L P Y +G G P +GI+PN+ELI+E+ + S + Sbjct: 192 EGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFE 251 Query: 393 *CAMRFMMD 419 + MD Sbjct: 252 KAKESWEMD 260
>FKB1B_ASPFU (Q4W9R2) FK506-binding protein 1B (EC 5.2.1.8) (FKBP)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rapamycin-binding protein) Length = 120 Score = 84.3 bits (207), Expect = 2e-16 Identities = 52/118 (44%), Positives = 66/118 (55%), Gaps = 6/118 (5%) Frame = +3 Query: 57 MGIQKEILRAGTGPK-PVKGQKVTVHCTGY-----GKDGDLSKKFWSTKDPGQQPFAFNI 218 MG++K+ LR G G P G V ++ TGY D K+F S+K G P I Sbjct: 1 MGLEKQTLRMGNGKDHPQPGDPVELNYTGYLYDESNPDHHKGKEFDSSKRRG--PLKATI 58 Query: 219 GLGSVIKGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVLSAK 392 G G VI+GWDEGV M LGE A L + +YAYG G P I PN+ L+FE+E+L K Sbjct: 59 GAGDVIRGWDEGVRQMSLGEKAILTMSGEYAYGEKGFPGL-IPPNASLVFEVELLKIK 115
>FKB70_WHEAT (Q43207) 70 kDa peptidyl-prolyl isomerase (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) Length = 559 Score = 84.0 bits (206), Expect = 3e-16 Identities = 51/115 (44%), Positives = 68/115 (59%), Gaps = 1/115 (0%) Frame = +3 Query: 45 EDGKMGIQKEILRAGTG-PKPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIG 221 E GK G++K++L+ G G P G +V VH TG DG KKF S++D F F +G Sbjct: 37 EIGKQGLKKKLLKEGEGWDTPEVGDEVEVHYTGTLLDG---KKFDSSRDR-DDTFKFKLG 92 Query: 222 LGSVIKGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVLS 386 G VIKGWD+G+ M+ GE A P+ AYG GSP I N+ L F++E+LS Sbjct: 93 QGQVIKGWDQGIKTMKKGENALFTIPPELAYGESGSPP-TIPANATLQFDVELLS 146 Score = 65.5 bits (158), Expect = 1e-10 Identities = 43/110 (39%), Positives = 63/110 (57%), Gaps = 2/110 (1%) Frame = +3 Query: 63 IQKEILRAGTG-PKPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIK 239 I K++L+ G +P +G VTV TG +DG + F Q+PF F +VI+ Sbjct: 276 ILKKVLKEXEGYERPNEGAVVTVKITGKLQDGTV---FLKKGHDEQEPFEFKTDEEAVIE 332 Query: 240 GWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGI-QPNSELIFEIEVLS 386 G D V++M+ GEVA + P+YAYGS S I PNS +I+E+E++S Sbjct: 333 GLDRAVLNMKKGEVALVTIPPEYAYGSTESKQDAIVPPNSTVIYEVELVS 382 Score = 40.4 bits (93), Expect = 0.003 Identities = 36/125 (28%), Positives = 55/125 (44%), Gaps = 5/125 (4%) Frame = +3 Query: 33 RGDAEDGKMGIQKEILRAGTG-PKPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFA 209 R A+DG GI K+IL+ G P +V V +DG + K + Sbjct: 151 RDIAKDG--GIFKKILKEGDKWENPKDPDEVFVKYEARLEDGTVVSK--------SEGVE 200 Query: 210 FNIGLGSVIKGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWG----IQPNSELIFEIE 377 F + G + + V M+ GE L P Y +G G PA G + PN+ L+ ++E Sbjct: 201 FTVKDGHLCPALAKAVKTMKKGEKVLLAVKPQYGFGEMGRPAAGEGGAVPPNASLVIDLE 260 Query: 378 VLSAK 392 ++S K Sbjct: 261 LVSWK 265
>FKBP5_SAGOE (Q9XSI2) FK506-binding protein 5 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (51 kDa FK506-binding immunophilin) (FKBP-51) Length = 457 Score = 83.6 bits (205), Expect = 3e-16 Identities = 51/112 (45%), Positives = 67/112 (59%), Gaps = 1/112 (0%) Frame = +3 Query: 60 GIQKEILRAGTGPK-PVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVI 236 G+ K + R G G + P+ G KV VH G +G KKF S+ D + PF F+IG G VI Sbjct: 32 GVLKIVKRVGHGEETPMIGDKVYVHYNGKLSNG---KKFDSSHDRNE-PFVFSIGKGQVI 87 Query: 237 KGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVLSAK 392 K WD GV M+ GE+ L C P+YAYG+ GS I N+ L FE+E+L+ K Sbjct: 88 KAWDIGVSTMKKGEICHLLCKPEYAYGATGSLP-KIPSNATLFFEVELLNFK 138 Score = 51.6 bits (122), Expect = 1e-06 Identities = 40/129 (31%), Positives = 61/129 (47%), Gaps = 4/129 (3%) Frame = +3 Query: 45 EDGKMGIQKEILRAGTG-PKPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIG 221 EDG GI + R G G P +G +V +H +G + + +D AF +G Sbjct: 144 EDG--GIIRRTKRRGEGYSNPNEGARVQIHL-----EGRCGGRVFDCRD-----VAFTVG 191 Query: 222 LGS---VIKGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVLSAK 392 G + G D+ + MQ E L P Y +G G P +GI+PN+ELI+E+ + S + Sbjct: 192 EGEDHDIPIGIDKALEKMQREEQCILHLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFE 251 Query: 393 *CAMRFMMD 419 + MD Sbjct: 252 KAKESWEMD 260
>FKBP5_AOTNA (Q9XT11) FK506-binding protein 5 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (51 kDa FK506-binding immunophilin) (FKBP-51) Length = 457 Score = 83.6 bits (205), Expect = 3e-16 Identities = 52/112 (46%), Positives = 66/112 (58%), Gaps = 1/112 (0%) Frame = +3 Query: 60 GIQKEILRAGTGPK-PVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVI 236 G+ K + R G G + P+ G KV VH G +G KKF S+ D + PF F+IG G VI Sbjct: 32 GVLKIVKRVGHGEETPMIGDKVYVHYNGKLSNG---KKFDSSHDRNE-PFVFSIGKGQVI 87 Query: 237 KGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVLSAK 392 K WD GV M+ GE+ L C P+YAYG+ GS I N+ L FEIE+L K Sbjct: 88 KAWDIGVATMKKGEICHLLCKPEYAYGATGSLP-KIPSNATLFFEIELLDFK 138 Score = 51.6 bits (122), Expect = 1e-06 Identities = 40/129 (31%), Positives = 61/129 (47%), Gaps = 4/129 (3%) Frame = +3 Query: 45 EDGKMGIQKEILRAGTG-PKPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIG 221 EDG GI + R G G P +G +V +H +G + + +D AF +G Sbjct: 144 EDG--GIIRRTKRRGEGYSNPNEGARVQIHL-----EGRCGGRVFDCRD-----VAFTVG 191 Query: 222 LGS---VIKGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVLSAK 392 G + G D+ + MQ E L P Y +G G P +GI+PN+ELI+E+ + S + Sbjct: 192 EGEDHDIPIGIDKALEKMQREEQCILHLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFE 251 Query: 393 *CAMRFMMD 419 + MD Sbjct: 252 KAKESWEMD 260
>FKBP5_CERAE (Q95L05) FK506-binding protein 5 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (51 kDa FK506-binding immunophilin) (FKBP-51) Length = 457 Score = 83.2 bits (204), Expect = 5e-16 Identities = 51/112 (45%), Positives = 65/112 (58%), Gaps = 1/112 (0%) Frame = +3 Query: 60 GIQKEILRAGTGPK-PVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVI 236 G+ K + R G G + P+ G KV VH G +G KKF S+ D + PF F++G VI Sbjct: 32 GVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNG---KKFNSSHDRNE-PFVFSLGKSQVI 87 Query: 237 KGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVLSAK 392 K WD GV M+ GE+ L C P+YAYGS GS I N+ L FEIE+L K Sbjct: 88 KAWDIGVATMKKGEICHLLCKPEYAYGSAGSVP-KIPSNATLFFEIELLDFK 138 Score = 51.6 bits (122), Expect = 1e-06 Identities = 40/129 (31%), Positives = 61/129 (47%), Gaps = 4/129 (3%) Frame = +3 Query: 45 EDGKMGIQKEILRAGTG-PKPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIG 221 EDG GI + R G G P +G V +H +G ++ + +D AF +G Sbjct: 144 EDG--GIIRRTKRKGEGYSNPNEGATVEIHL-----EGRCGERMFDCRD-----VAFTVG 191 Query: 222 LGS---VIKGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVLSAK 392 G + G D+ + MQ E L P Y +G G P +GI+PN+ELI+E+ + S + Sbjct: 192 EGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFE 251 Query: 393 *CAMRFMMD 419 + MD Sbjct: 252 KAKESWEMD 260
>FKB1A_MOUSE (P26883) FK506-binding protein 1A (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) (12 kDa FKBP) (FKBP-12) (Immunophilin FKBP12) Length = 107 Score = 82.4 bits (202), Expect = 8e-16 Identities = 47/109 (43%), Positives = 68/109 (62%), Gaps = 1/109 (0%) Frame = +3 Query: 60 GIQKEILRAGTGPK-PVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVI 236 G+Q E + G G P +GQ VH TG +DG KKF S++D + PF F +G VI Sbjct: 1 GVQVETISPGDGRTFPKRGQTCVVHYTGMLEDG---KKFDSSRDRNK-PFKFTLGKQEVI 56 Query: 237 KGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVL 383 +GW+EGV M +G+ A+L + DYAYG+ G P I P++ L+F++E+L Sbjct: 57 RGWEEGVAQMSVGQRAKLIISSDYAYGATGHPGI-IPPHATLVFDVELL 104
>FKBP_YARLI (Q6CF41) FK506-binding protein 1 (EC 5.2.1.8) (FKBP)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rapamycin-binding protein) Length = 108 Score = 82.4 bits (202), Expect = 8e-16 Identities = 48/110 (43%), Positives = 68/110 (61%), Gaps = 1/110 (0%) Frame = +3 Query: 57 MGIQKEILRAGTGPK-PVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSV 233 MG+ + L+ G G P KG VT+H G ++G +KF S++D G+ PF IG+G V Sbjct: 1 MGVTVKQLQPGDGKTYPKKGDAVTIHYVGTLENG---QKFDSSRDRGE-PFKTTIGVGDV 56 Query: 234 IKGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVL 383 I+GWDEGV + LGE + L + DY YG G P I PN+ L+F++E+L Sbjct: 57 IRGWDEGVPKLSLGERSVLTISGDYGYGERGFPGL-IPPNATLVFDVELL 105
>FKBP5_SAIBB (Q9XSH5) FK506-binding protein 5 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (51 kDa FK506-binding immunophilin) (FKBP-51) Length = 457 Score = 81.6 bits (200), Expect = 1e-15 Identities = 50/112 (44%), Positives = 66/112 (58%), Gaps = 1/112 (0%) Frame = +3 Query: 60 GIQKEILRAGTGPK-PVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVI 236 G+ K + R G G + P+ G +V VH G +G KKF S+ D + PF F+IG G VI Sbjct: 32 GVLKIVKRVGHGEETPMIGDRVYVHYNGKLANG---KKFDSSHDRNE-PFVFSIGKGQVI 87 Query: 237 KGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVLSAK 392 K WD GV M+ GE+ L C P+YAYG+ GS I N+ L FE+E+L K Sbjct: 88 KAWDIGVATMKKGEICHLLCKPEYAYGATGSLP-KIPSNATLFFEVELLDFK 138 Score = 51.6 bits (122), Expect = 1e-06 Identities = 40/129 (31%), Positives = 61/129 (47%), Gaps = 4/129 (3%) Frame = +3 Query: 45 EDGKMGIQKEILRAGTG-PKPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIG 221 EDG GI + R G G P +G +V +H +G + + +D AF +G Sbjct: 144 EDG--GIIRRTKRRGEGYSNPNEGARVQIHL-----EGRCGGRVFDCRD-----VAFTVG 191 Query: 222 LGS---VIKGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVLSAK 392 G + G D+ + MQ E L P Y +G G P +GI+PN+ELI+E+ + S + Sbjct: 192 EGEDHDIPIGIDKALEKMQREEQCILHLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFE 251 Query: 393 *CAMRFMMD 419 + MD Sbjct: 252 KAKESWEMD 260
>FKBP3_BOVIN (P26884) FK506-binding protein 3 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) (25 kDa FKBP) (FKBP-25) (Rapamycin-selective 25 kDa immunophilin) Length = 224 Score = 81.6 bits (200), Expect = 1e-15 Identities = 45/117 (38%), Positives = 67/117 (57%), Gaps = 4/117 (3%) Frame = +3 Query: 45 EDGKMGIQKEILRAGTGPK-PVKGQKVTVHCTGYGKDG---DLSKKFWSTKDPGQQPFAF 212 ++G K +L+ G P KG V TG +DG D + + S K +P +F Sbjct: 105 DEGPPKYTKSVLKKGDKTNFPKKGDVVHCWYTGTLQDGTVFDTNIQTSSKKKKNAKPLSF 164 Query: 213 NIGLGSVIKGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVL 383 +G+G VI+GWDE ++ M GE ARL+ P++AYG G P I PN++LIFE+E++ Sbjct: 165 KVGIGKVIRGWDEALLTMSKGEKARLEIEPEWAYGKKGQPDAKIPPNAKLIFEVELV 221
>FKBP3_RABIT (O46638) FK506-binding protein 3 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) (25 kDa FKBP) (FKBP-25) (Rapamycin-selective 25 kDa immunophilin) (Fragment) Length = 223 Score = 81.3 bits (199), Expect = 2e-15 Identities = 45/117 (38%), Positives = 67/117 (57%), Gaps = 4/117 (3%) Frame = +3 Query: 45 EDGKMGIQKEILRAGTGPK-PVKGQKVTVHCTGYGKDG---DLSKKFWSTKDPGQQPFAF 212 ++G K +L+ G P KG V TG +DG D + + S K +P +F Sbjct: 104 DEGPPKYTKSVLKKGDKTNFPKKGDVVHCWYTGTLQDGTVFDTNIQTSSKKKKNAKPLSF 163 Query: 213 NIGLGSVIKGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVL 383 +G+G VI+GWDE ++ M GE ARL+ P++AYG G P I PN++LIFE+E++ Sbjct: 164 KVGVGKVIRGWDEALLTMSKGEKARLEIEPEWAYGKKGQPDAKIPPNAKLIFEVELV 220
>FKBP3_MOUSE (Q62446) FK506-binding protein 3 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) (25 kDa FKBP) (FKBP-25) (Rapamycin-selective 25 kDa immunophilin) Length = 224 Score = 80.9 bits (198), Expect = 2e-15 Identities = 46/117 (39%), Positives = 66/117 (56%), Gaps = 4/117 (3%) Frame = +3 Query: 45 EDGKMGIQKEILRAGTGPK-PVKGQKVTVHCTGYGKDG---DLSKKFWSTKDPGQQPFAF 212 ++G K IL+ G P KG V TG DG D + + S K +P +F Sbjct: 105 DEGPPKYTKSILKKGDKTNFPKKGDVVHCWYTGTLPDGTVFDTNIQTSSKKKKNAKPLSF 164 Query: 213 NIGLGSVIKGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVL 383 +G+G VI+GWDE ++ M GE ARL+ P++AYG G P I PN++LIFE+E++ Sbjct: 165 KVGVGKVIRGWDEALLTMSKGEKARLEIEPEWAYGKKGQPDAKIPPNTKLIFEVELV 221
>FKBP_CANGA (Q6FMA3) FK506-binding protein 1 (EC 5.2.1.8) (FKBP)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rapamycin-binding protein) Length = 114 Score = 80.5 bits (197), Expect = 3e-15 Identities = 49/109 (44%), Positives = 66/109 (60%), Gaps = 1/109 (0%) Frame = +3 Query: 60 GIQKEILRAGTGPK-PVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVI 236 G++ + L G G P +G VT+H TG ++G +KF S+ D G PF NIG+G VI Sbjct: 8 GVKIDRLSPGDGKTFPKQGDLVTIHYTGTLENG---QKFDSSVDRGS-PFQCNIGVGQVI 63 Query: 237 KGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVL 383 KGWD G+ + +GE ARL YAYG G P I PN+ LIF++E+L Sbjct: 64 KGWDAGIPKLSVGEKARLTIPGPYAYGPRGFPGL-IPPNATLIFDVELL 111
>FKBP_YEAST (P20081) FK506-binding protein 1 (FKBP) (Peptidyl-prolyl cis-trans| isomerase) (PPIase) (EC 5.2.1.8) (Rapamycin-binding protein) Length = 114 Score = 78.2 bits (191), Expect = 1e-14 Identities = 45/94 (47%), Positives = 58/94 (61%) Frame = +3 Query: 102 PVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIKGWDEGVMDMQLGEV 281 P G VT+H TG ++G +KF S+ D G PF NIG+G VIKGWD G+ + +GE Sbjct: 23 PKTGDLVTIHYTGTLENG---QKFDSSVDRGS-PFQCNIGVGQVIKGWDVGIPKLSVGEK 78 Query: 282 ARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVL 383 ARL YAYG G P I PNS L+F++E+L Sbjct: 79 ARLTIPGPYAYGPRGFPGL-IPPNSTLVFDVELL 111
>FKBP3_HUMAN (Q00688) FK506-binding protein 3 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) (25 kDa FKBP) (FKBP-25) (Rapamycin-selective 25 kDa immunophilin) Length = 224 Score = 78.2 bits (191), Expect = 1e-14 Identities = 43/117 (36%), Positives = 66/117 (56%), Gaps = 4/117 (3%) Frame = +3 Query: 45 EDGKMGIQKEILRAGTGPK-PVKGQKVTVHCTGYGKDG---DLSKKFWSTKDPGQQPFAF 212 ++G K +L+ G P KG V TG +DG D + + + K +P +F Sbjct: 105 DEGPPKYTKSVLKKGDKTNFPKKGDVVHCWYTGTLQDGTVFDTNIQTSAKKKKNAKPLSF 164 Query: 213 NIGLGSVIKGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVL 383 +G+G VI+GWDE ++ M GE ARL+ P++AYG G P I PN++L FE+E++ Sbjct: 165 KVGVGKVIRGWDEALLTMSKGEKARLEIEPEWAYGKKGQPDAKIPPNAKLTFEVELV 221
>FKB1B_NEUCR (Q6M981) FK506-binding protein 1B (EC 5.2.1.8) (FKBP)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rapamycin-binding protein) Length = 110 Score = 77.4 bits (189), Expect = 2e-14 Identities = 43/106 (40%), Positives = 60/106 (56%) Frame = +3 Query: 57 MGIQKEILRAGTGPKPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVI 236 MG+ K AGTGP+P GQ V + TG+ KD + G+ F IG+G +I Sbjct: 1 MGVNKITHVAGTGPQPEAGQTVVIEYTGWLKDSSQADGK-GADSIGRGDFVTQIGVGRLI 59 Query: 237 KGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEI 374 +GWDE V+ M++GE A L + DY YG G I PN++LIF++ Sbjct: 60 RGWDEAVLKMKVGEKATLDISSDYGYGERGFHG-HIPPNADLIFDV 104
>FKBP_KLULA (Q6CX30) FK506-binding protein 1 (EC 5.2.1.8) (FKBP)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rapamycin-binding protein) Length = 114 Score = 77.0 bits (188), Expect = 3e-14 Identities = 49/109 (44%), Positives = 64/109 (58%), Gaps = 5/109 (4%) Frame = +3 Query: 72 EILRAGTG-----PKPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVI 236 +ILR G PKP G VT+H TG ++G +KF S+ D G PF NIG+G VI Sbjct: 10 QILRLSPGDSTNFPKP--GDLVTIHYTGTLENG---QKFDSSVDRGS-PFQCNIGVGQVI 63 Query: 237 KGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVL 383 KGWD + + +GE ARL YAYG G P I PN+ L+F++E+L Sbjct: 64 KGWDAAIPKLSVGEKARLTIPGPYAYGPRGFPGL-IPPNATLVFDVELL 111
>FKB70_ARATH (Q38931) 70 kDa peptidyl-prolyl isomerase (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (Peptidylprolyl isomerase ROF1) Length = 551 Score = 75.9 bits (185), Expect = 7e-14 Identities = 47/117 (40%), Positives = 68/117 (58%), Gaps = 1/117 (0%) Frame = +3 Query: 36 GDAEDGKMGIQKEILRAGTGPK-PVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAF 212 G+ ++ + G++K++L+ G G + P G +V VH TG DG KF S++D PF F Sbjct: 31 GEEKEIQQGLKKKLLKEGEGYETPENGDEVEVHYTGTLLDGT---KFDSSRDRAT-PFKF 86 Query: 213 NIGLGSVIKGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVL 383 +G G VIKGWD G+ M+ GE A + AYG GSP I N+ L F++E+L Sbjct: 87 TLGQGQVIKGWDIGIKTMKKGENAVFTIPAELAYGESGSPP-TIPANATLQFDVELL 142 Score = 55.5 bits (132), Expect = 1e-07 Identities = 36/111 (32%), Positives = 58/111 (52%), Gaps = 3/111 (2%) Frame = +3 Query: 63 IQKEILRAGTG-PKPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIK 239 + K++L+ G G +P +G V V G +DG + K ++PF F V+ Sbjct: 273 VVKKVLKEGDGYERPNEGAVVKVKLIGKLQDGTVFLK--KGHGENEEPFEFKTDEEQVVD 330 Query: 240 GWDEGVMDMQLGEVARLKCTPDYAYGSGGS--PAWGIQPNSELIFEIEVLS 386 G D VM M+ GEVA + P+YA+GS S + PNS + +E+++L+ Sbjct: 331 GLDRAVMKMKKGEVALVTIDPEYAFGSNESQQELAVVPPNSTVTYEVDLLT 381 Score = 31.2 bits (69), Expect = 2.0 Identities = 19/65 (29%), Positives = 28/65 (43%), Gaps = 4/65 (6%) Frame = +3 Query: 210 FNIGLGSVIKGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPA----WGIQPNSELIFEIE 377 F + G + V M+ GE L P Y +G G PA + PN+ L +E Sbjct: 198 FTVKDGHFCPALTKAVKTMKKGEKVLLTVKPQYGFGEKGKPASAGEGAVPPNATLEINLE 257 Query: 378 VLSAK 392 ++S K Sbjct: 258 LVSWK 262
>FKBP_DEBHA (Q6BX45) FK506-binding protein 1 (EC 5.2.1.8) (FKBP)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rapamycin-binding protein) Length = 112 Score = 75.5 bits (184), Expect = 9e-14 Identities = 48/110 (43%), Positives = 66/110 (60%), Gaps = 3/110 (2%) Frame = +3 Query: 66 QKEILRAGTG---PKPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVI 236 Q EIL+ G G PKP G VT+H TG ++G KKF S++D G+ PF IG+G VI Sbjct: 8 QVEILQEGDGKTFPKP--GDLVTIHYTGTLENG---KKFDSSRDRGK-PFQCTIGVGQVI 61 Query: 237 KGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVLS 386 GWD G+ + +G A+L AYG G P I PN+ L+F++E+L+ Sbjct: 62 VGWDTGIPKLSVGSRAKLSIPGHEAYGDRGFPGL-IPPNATLLFDVELLN 110
>FKBP4_USTMA (Q4PIN7) FK506-binding protein 4 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) Length = 375 Score = 75.1 bits (183), Expect = 1e-13 Identities = 45/111 (40%), Positives = 61/111 (54%) Frame = +3 Query: 60 GIQKEILRAGTGPKPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIK 239 G+ E AG+GP GQKV + G +G + + S K PF F +G G VIK Sbjct: 272 GLVIEEKSAGSGPPCKAGQKVGMRYVGKLTNGKVFDQCTSGK-----PFYFKLGKGEVIK 326 Query: 240 GWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVLSAK 392 GWDEGV M++G RL C P AYG+ P GI NS L+F+++++ K Sbjct: 327 GWDEGVKGMRVGAERRLTCPPKLAYGNQKIP--GIPANSTLVFDVKLVEIK 375
>FKBP_ASHGO (Q754K8) FK506-binding protein 1 (EC 5.2.1.8) (FKBP)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rapamycin-binding protein) Length = 114 Score = 73.6 bits (179), Expect = 4e-13 Identities = 44/94 (46%), Positives = 56/94 (59%) Frame = +3 Query: 102 PVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIKGWDEGVMDMQLGEV 281 P G VT+H TG ++ +KF S+ D G PF NIG+G VIKGWD + + +GE Sbjct: 23 PKTGDLVTIHYTGTLEN---EQKFDSSVDRGS-PFQCNIGVGQVIKGWDVAIPKLSVGEK 78 Query: 282 ARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVL 383 ARL YAYG G P I PN+ LIFE+E+L Sbjct: 79 ARLTIPGAYAYGPRGFPGL-IPPNATLIFEVELL 111
>FKBP_NEIMB (P0A0W2) FK506-binding protein (Peptidyl-prolyl cis-trans| isomerase) (PPIase) (EC 5.2.1.8) (Rotamase) Length = 109 Score = 73.2 bits (178), Expect = 5e-13 Identities = 44/108 (40%), Positives = 66/108 (61%) Frame = +3 Query: 60 GIQKEILRAGTGPKPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIK 239 G+ E L+ G G + VKG+++TVH TG+ ++G KF S+ D +QP +G+G VIK Sbjct: 3 GLIIEDLQEGFGKEAVKGKEITVHYTGWLENGT---KFDSSLDR-RQPLTITLGVGQVIK 58 Query: 240 GWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVL 383 GWDEG M+ G +L + YG+ G+ I P++ LIFE+E+L Sbjct: 59 GWDEGFGGMKEGGKRKLTIPSEMGYGAHGA-GGVIPPHATLIFEVELL 105
>FKB1A_NEUCR (P20080) FK506-binding protein 1A (FKBP) (Peptidyl-prolyl cis-trans| isomerase) (PPIase) (EC 5.2.1.8) Length = 120 Score = 73.2 bits (178), Expect = 5e-13 Identities = 47/113 (41%), Positives = 64/113 (56%), Gaps = 2/113 (1%) Frame = +3 Query: 60 GIQKEILRAGTGPKPVK-GQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVI 236 G+Q E+ + G G + + G V VH G G KKF ++ D G+ P F +G G VI Sbjct: 8 GLQIEVQQEGQGTRETRRGDNVDVHYKGVLTSG---KKFDASYDRGE-PLNFTVGQGQVI 63 Query: 237 KGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQP-NSELIFEIEVLSAK 392 KGWDEG++ M++GE +L P AYG+ GI P NS LIFE E++ K Sbjct: 64 KGWDEGLLGMKIGEKRKLTIAPHLAYGN--RAVGGIIPANSTLIFETELVGIK 114
>FKBP_NEIMA (P56989) FK506-binding protein (Peptidyl-prolyl cis-trans| isomerase) (PPIase) (EC 5.2.1.8) (Rotamase) Length = 109 Score = 72.4 bits (176), Expect = 8e-13 Identities = 43/104 (41%), Positives = 64/104 (61%) Frame = +3 Query: 72 EILRAGTGPKPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIKGWDE 251 E L+ G G + VKG+++TVH TG+ ++G KF S+ D +QP +G+G VIKGWDE Sbjct: 7 EDLQEGFGKEAVKGKEITVHYTGWLENGT---KFDSSLDR-RQPLTITLGVGQVIKGWDE 62 Query: 252 GVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVL 383 G M+ G +L + YG+ G+ I P++ LIFE+E+L Sbjct: 63 GFGGMKEGGKRKLTIPSEMGYGARGA-GGVIPPHATLIFEVELL 105
>FKBP2_CRYNE (Q5KGT9) FK506-binding protein 2 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) Length = 141 Score = 72.4 bits (176), Expect = 8e-13 Identities = 43/99 (43%), Positives = 58/99 (58%), Gaps = 1/99 (1%) Frame = +3 Query: 99 KPVKGQKVTVHCTG-YGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIKGWDEGVMDMQLG 275 K KG ++++H TG KDG KF S+ D + PF F +G G VIKGWD+G++DM + Sbjct: 41 KSRKGDRLSMHYTGTLAKDGS---KFDSSLDRNR-PFEFTLGAGQVIKGWDQGLLDMCIS 96 Query: 276 EVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVLSAK 392 E +L AYG G P I P S L+FE+E+L K Sbjct: 97 EKRKLTIPSHLAYGERGHPP-VIPPQSTLVFEVELLGIK 134
>FKBP_NEIMC (P0A0W3) FK506-binding protein (Peptidyl-prolyl cis-trans| isomerase) (PPIase) (EC 5.2.1.8) (Rotamase) Length = 109 Score = 72.0 bits (175), Expect = 1e-12 Identities = 43/104 (41%), Positives = 63/104 (60%) Frame = +3 Query: 72 EILRAGTGPKPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIKGWDE 251 E L+ G + VKG+++TVH TG+ +DG KF S+ D +QP +G+G VIKGWDE Sbjct: 7 EDLQESFGKEAVKGKEITVHYTGWLEDGT---KFDSSLDR-RQPLTITLGVGQVIKGWDE 62 Query: 252 GVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVL 383 G M+ G +L + YG+ G+ I P++ LIFE+E+L Sbjct: 63 GFGGMKEGGKRKLTIPSEMGYGAHGA-GGVIPPHATLIFEVELL 105
>FKBP3_CANGA (Q6FKH7) FK506-binding protein 3 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) Length = 437 Score = 71.6 bits (174), Expect = 1e-12 Identities = 44/111 (39%), Positives = 57/111 (51%) Frame = +3 Query: 60 GIQKEILRAGTGPKPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIK 239 G+ E G GP KG +V + G K+G + K S K PF F +G G VIK Sbjct: 334 GVVIEDRTVGDGPAAKKGDRVGMRYIGKLKNGKVFDKNTSGK-----PFVFKLGRGEVIK 388 Query: 240 GWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVLSAK 392 GWD GV M +G R+ YAYG P GI NSEL F+++++S K Sbjct: 389 GWDVGVAGMSVGSERRIIIPAPYAYGKQALP--GIPANSELTFDVKLVSIK 437
>FKBP3_YEAST (P38911) FK506-binding nuclear protein (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Proline rotamase) (Nucleolar proline isomerase) (FKBP-70) Length = 411 Score = 71.2 bits (173), Expect = 2e-12 Identities = 45/111 (40%), Positives = 59/111 (53%) Frame = +3 Query: 60 GIQKEILRAGTGPKPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIK 239 GI E G GP+ +G +V + G K+G + K S K PFAF +G G VIK Sbjct: 307 GIVIEDRTIGDGPQAKRGARVGMRYIGKLKNGKVFDKNTSGK-----PFAFKLGRGEVIK 361 Query: 240 GWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVLSAK 392 GWD GV M +G R+ YAYG P GI NSEL F+++++S K Sbjct: 362 GWDIGVAGMSVGGERRIIIPAPYAYGKQALP--GIPANSELTFDVKLVSMK 410
>FKBP4_CANGA (Q6FK71) FK506-binding protein 4 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) Length = 398 Score = 70.1 bits (170), Expect = 4e-12 Identities = 45/111 (40%), Positives = 58/111 (52%) Frame = +3 Query: 60 GIQKEILRAGTGPKPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIK 239 G+ E + G GPK KG KV + G K+G + K S K PF F + G VIK Sbjct: 295 GVIIEDRKIGEGPKAKKGSKVGMRYIGKLKNGKVFDKNTSGK-----PFYFKLHRGEVIK 349 Query: 240 GWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVLSAK 392 GWD GV M +G R+ YAYG P GI NSEL F+++++S K Sbjct: 350 GWDIGVTGMAIGGERRIVIPAPYAYGKQTLP--GIPANSELTFDVKLVSLK 398
>FKBP2_YEAST (P32472) FK506-binding protein 2 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (FKBP-13) (FKBP-15) Length = 135 Score = 69.7 bits (169), Expect = 5e-12 Identities = 45/119 (37%), Positives = 64/119 (53%) Frame = +3 Query: 36 GDAEDGKMGIQKEILRAGTGPKPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFN 215 G D ++GI K I K + G KV VH TG + F S+ G P AF Sbjct: 18 GSLSDLEIGIIKRIPVEDCLIKAMPGDKVKVHYTGSLLES--GTVFDSSYSRGS-PIAFE 74 Query: 216 IGLGSVIKGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVLSAK 392 +G+G VIKGWD+GV M +GE +L+ AYG G P I P+++L+F++E++ K Sbjct: 75 LGVGRVIKGWDQGVAGMCVGEKRKLQIPSSLAYGERGVPG-VIPPSADLVFDVELVDVK 132
>FKBP3_KLULA (Q6CWE8) FK506-binding protein 3 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) Length = 418 Score = 69.3 bits (168), Expect = 7e-12 Identities = 46/111 (41%), Positives = 57/111 (51%) Frame = +3 Query: 60 GIQKEILRAGTGPKPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIK 239 GI E G G KG KV + G K+G + K S K PF FN+G G VIK Sbjct: 315 GIIIEDRVTGKGKACKKGSKVGMRYIGKLKNGKVFDKNTSGK-----PFVFNLGRGEVIK 369 Query: 240 GWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVLSAK 392 GWD GV M +G R+ YAYG P GI NSEL F+++++S K Sbjct: 370 GWDIGVAGMAVGGERRIVIPAPYAYGKQALP--GIPANSELTFDVKLVSLK 418
>FKBP4_YEAST (Q06205) FK506-binding protein 4 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) Length = 392 Score = 68.9 bits (167), Expect = 9e-12 Identities = 45/111 (40%), Positives = 59/111 (53%) Frame = +3 Query: 60 GIQKEILRAGTGPKPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIK 239 GI E G GP KG +V + G K+G + K +TK +PF F +G G VIK Sbjct: 289 GIIIEDRVTGKGPHAKKGTRVGMRYVGKLKNGKVFDK--NTKG---KPFVFKLGQGEVIK 343 Query: 240 GWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVLSAK 392 GWD GV M +G R+ YAYG P GI NSEL F+++++S K Sbjct: 344 GWDIGVAGMAVGGERRIVIPAPYAYGKQALP--GIPANSELTFDVKLVSMK 392
>FKBP4_SPOFR (Q26486) 46 kDa FK506-binding nuclear protein (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) Length = 412 Score = 68.9 bits (167), Expect = 9e-12 Identities = 43/112 (38%), Positives = 62/112 (55%), Gaps = 1/112 (0%) Frame = +3 Query: 60 GIQKEILRAGTGPKPVKGQKVTVHCTGYGKDGDLSKKFWS-TKDPGQQPFAFNIGLGSVI 236 G+ E L+ G+GP G+ V V+ G K + K F + K PG F F +G VI Sbjct: 307 GVSIEDLKVGSGPVAKAGKVVMVYYEGRLKQNN--KMFDNCVKGPG---FKFRLGSKEVI 361 Query: 237 KGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVLSAK 392 GWD G+ M++G ++ C P AYG+ GSP I PNS L+FE+++ + K Sbjct: 362 SGWDVGIAGMKVGGKRKIVCPPAMAYGAKGSPP-VIPPNSTLVFEVDLKNVK 412
>FKBP2_YARLI (Q6CGG3) FK506-binding protein 2 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) Length = 144 Score = 68.9 bits (167), Expect = 9e-12 Identities = 45/111 (40%), Positives = 63/111 (56%) Frame = +3 Query: 54 KMGIQKEILRAGTGPKPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSV 233 ++GI K+I K KG V+VH TG +DG + F S+ + GQ P F +G G V Sbjct: 29 QIGILKKISPEECTQKARKGDTVSVHYTGKLEDGTV---FDSSVERGQ-PIQFPLGTGRV 84 Query: 234 IKGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVLS 386 I GWD+G++ M +GE +L P AYG G+ I P+S LIF E++S Sbjct: 85 IPGWDQGILGMCVGEKRKLTIPPHLAYGKQGA-GRVIPPDSTLIFTTELVS 134
>FKBP2_PODAN (Q86ZF2) FK506-binding protein 2 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) Length = 185 Score = 67.4 bits (163), Expect = 3e-11 Identities = 40/92 (43%), Positives = 51/92 (55%) Frame = +3 Query: 108 KGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIKGWDEGVMDMQLGEVAR 287 KG K+ VH G K +KF S+ D Q PF+F +G G VIKGWDEG++DM +GE Sbjct: 40 KGDKINVHYKGTLKSN--GEKFDSSYDR-QSPFSFKLGAGMVIKGWDEGLVDMCIGEKRT 96 Query: 288 LKCTPDYAYGSGGSPAWGIQPNSELIFEIEVL 383 L P Y YG I S L+FE E++ Sbjct: 97 LTIGPSYGYGDRN--VGPIPAGSTLVFETELV 126
>FKBP4_ASPOR (Q2UN37) FK506-binding protein 4 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) Length = 470 Score = 67.4 bits (163), Expect = 3e-11 Identities = 41/111 (36%), Positives = 57/111 (51%) Frame = +3 Query: 60 GIQKEILRAGTGPKPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIK 239 G++ + + G GP G V + G +DG K + G+ PF F +G G VIK Sbjct: 367 GVKIDDKKLGKGPAAKAGNTVAMRYIGKLEDG----KVFDANKKGK-PFTFKLGKGEVIK 421 Query: 240 GWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVLSAK 392 GWD GV M +G R+ P AYG P GI NS+LIF++++L K Sbjct: 422 GWDIGVAGMAVGGERRISIPPHLAYGKKALP--GIPGNSKLIFDVKLLEIK 470
>FKBP4_ASPFU (Q4WMV5) FK506-binding protein 4 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) Length = 489 Score = 67.0 bits (162), Expect = 3e-11 Identities = 40/111 (36%), Positives = 57/111 (51%) Frame = +3 Query: 60 GIQKEILRAGTGPKPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIK 239 G++ + + G GP G V + G +DG K + G+ PF F +G G VIK Sbjct: 386 GVKIDDKKLGKGPAAKAGNTVAMRYIGKLEDG----KVFDANKKGK-PFTFKLGKGEVIK 440 Query: 240 GWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVLSAK 392 GWD G+ M +G R+ P AYG P GI NS+LIF++++L K Sbjct: 441 GWDIGIAGMAVGGERRITIPPHLAYGKKALP--GIPANSKLIFDVKLLEIK 489
>FKBP4_NEUCR (Q7SCN0) FK506-binding protein 4 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) Length = 467 Score = 67.0 bits (162), Expect = 3e-11 Identities = 44/111 (39%), Positives = 58/111 (52%) Frame = +3 Query: 60 GIQKEILRAGTGPKPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIK 239 G+ + + GTG G +V + G ++G K F S K PF+F +G G VIK Sbjct: 364 GVTIDDRKVGTGRAAKNGDRVGMRYIGKLQNG---KVFDSNKKGA--PFSFKLGKGEVIK 418 Query: 240 GWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVLSAK 392 GWD GV M +G RL AYGS P GI PNS LIF++++L K Sbjct: 419 GWDIGVAGMAVGGERRLTIPAHLAYGSRALP--GIPPNSTLIFDVKLLEIK 467
>FKBP3_ASHGO (Q756V1) FK506-binding protein 3 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) Length = 418 Score = 66.2 bits (160), Expect = 6e-11 Identities = 43/111 (38%), Positives = 57/111 (51%) Frame = +3 Query: 60 GIQKEILRAGTGPKPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIK 239 G+ E G+G KG +V + G K+G + K S K PF F +G G VIK Sbjct: 315 GVVIEDRVVGSGKAAKKGARVGMRYIGKLKNGKVFDKNTSGK-----PFVFKLGHGEVIK 369 Query: 240 GWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVLSAK 392 GWD GV M +G R+ YAYG P GI NSEL F+++++S K Sbjct: 370 GWDIGVAGMAVGGERRIVIPAAYAYGKQALP--GIPANSELTFDVKLVSLK 418
>FKBP3_YARLI (Q6C4C9) FK506-binding protein 3 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) Length = 407 Score = 66.2 bits (160), Expect = 6e-11 Identities = 41/111 (36%), Positives = 59/111 (53%) Frame = +3 Query: 60 GIQKEILRAGTGPKPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIK 239 G++ E G GP G KV V G +G K + + G+ PF F++G G VI+ Sbjct: 304 GVKIEDRTVGEGPSAKVGSKVGVRYVGKLANG----KVFDSNSKGK-PFYFSVGKGEVIR 358 Query: 240 GWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVLSAK 392 GWD GV M++ R+ P AYG P GI PNS+L F+++V++ K Sbjct: 359 GWDIGVQGMKVKGERRIIIPPGMAYGKQKLP--GIPPNSQLTFDVKVVNIK 407
>FKBP3_ARATH (Q9SCY2) FKBP-type peptidyl-prolyl cis-trans isomerase 3,| chloroplast precursor (EC 5.2.1.8) (PPIase) (Rotamase) (AtFKBP13) (FK506-binding protein 1) Length = 208 Score = 64.7 bits (156), Expect = 2e-10 Identities = 42/109 (38%), Positives = 59/109 (54%), Gaps = 10/109 (9%) Frame = +3 Query: 87 GTGPKPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIKGWDEGVM-- 260 G GP+ VKGQ + H G ++G K F S+ + G+ P F IG+G VIKGWD+G++ Sbjct: 101 GYGPEAVKGQLIKAHYVGKLENG---KVFDSSYNRGK-PLTFRIGVGEVIKGWDQGILGS 156 Query: 261 ----DMQLGEVARLKCTPDYAYGSGGSPAWG----IQPNSELIFEIEVL 383 M G L+ P+ AYG G+ G I P S L+F+IE + Sbjct: 157 DGIPPMLTGGKRTLRIPPELAYGDRGAGCKGGSCLIPPASVLLFDIEYI 205
>FKBP4_EMENI (P0C1B0) FK506-binding protein 4 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) Length = 478 Score = 64.7 bits (156), Expect = 2e-10 Identities = 41/104 (39%), Positives = 54/104 (51%) Frame = +3 Query: 81 RAGTGPKPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIKGWDEGVM 260 + G GP G V + G ++G K F S K +PF F +G G VIKGWD GV Sbjct: 382 KLGKGPAAASGNTVAMRYIGKLENG---KVFDSNKKG--KPFTFKLGKGEVIKGWDIGVA 436 Query: 261 DMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVLSAK 392 M +G R+ AYG G P GI NS+LIF++++L K Sbjct: 437 GMAVGGERRITIPSHLAYGKKGVP--GIPGNSKLIFDVKLLEIK 478
>FKBP4_GIBZE (Q4INZ9) FK506-binding protein 4 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) Length = 495 Score = 64.3 bits (155), Expect = 2e-10 Identities = 45/116 (38%), Positives = 58/116 (50%), Gaps = 12/116 (10%) Frame = +3 Query: 81 RAGTGPKPVKGQKVTVHCTGYG---KDGD-LSKKFWSTKDPGQQ--------PFAFNIGL 224 + TG K V+G V G G K GD + ++ G+Q PF+F G Sbjct: 382 KPATGVKVVQGVTVDDRTVGNGRTVKSGDTVGVRYIGKLQNGKQFDANKKGKPFSFKAGK 441 Query: 225 GSVIKGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVLSAK 392 G VIKGWD GV+ M +G RL AYGS G P GI NS LIF++++L K Sbjct: 442 GQVIKGWDIGVIGMAIGGERRLTIPAHLAYGSRGLP--GIPANSTLIFDVKLLEIK 495
>FKBP2_NEUCR (O60046) FK506-binding protein 2 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (FKBP-21) (NcFKBP22) Length = 217 Score = 63.9 bits (154), Expect = 3e-10 Identities = 41/98 (41%), Positives = 54/98 (55%), Gaps = 3/98 (3%) Frame = +3 Query: 99 KPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIKGWDEGVMDMQLGE 278 K KG K+ VH G + ++F ++ D G PF+F +G G VIKGWDEG++DM +GE Sbjct: 37 KTRKGDKINVHYRGTLQSN--GQQFDASYDRGT-PFSFKLGGGQVIKGWDEGLVDMCIGE 93 Query: 279 VARLKCTPDYAYGS---GGSPAWGIQPNSELIFEIEVL 383 L P Y YG G PA S LIFE E++ Sbjct: 94 KRTLTVPPSYGYGQRSIGPIPA-----GSTLIFETELI 126
>FKB39_DROME (P54397) 39 kDa FK506-binding nuclear protein (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) Length = 357 Score = 63.9 bits (154), Expect = 3e-10 Identities = 38/98 (38%), Positives = 58/98 (59%) Frame = +3 Query: 87 GTGPKPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIKGWDEGVMDM 266 G G + +G++V+V+ G + + K + + G+ PF F +G G VIKGWD GV M Sbjct: 261 GKGEEAKQGKRVSVYYIGRLQSNN---KTFDSLLKGK-PFKFALGGGEVIKGWDVGVAGM 316 Query: 267 QLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEV 380 ++G + C P AYG+ G+P I PNS L+FE+E+ Sbjct: 317 KVGGKRVITCPPHMAYGARGAPP-KIGPNSTLVFEVEL 353
>FKBP2_EMENI (Q5ATN7) FK506-binding protein 2 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) Length = 135 Score = 63.5 bits (153), Expect = 4e-10 Identities = 40/96 (41%), Positives = 53/96 (55%), Gaps = 1/96 (1%) Frame = +3 Query: 99 KPVKGQKVTVHCTG-YGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIKGWDEGVMDMQLG 275 K KG V +H G +DG +F ++ D G PF F +G G VIKGWDEG++DM +G Sbjct: 36 KTTKGDTVKMHYRGTLAEDGS---QFDASYDRGT-PFKFKLGAGRVIKGWDEGLLDMCVG 91 Query: 276 EVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVL 383 E L P+Y YG G I + LIF+ E+L Sbjct: 92 EKRTLTIPPEYGYGDRG--IGPIPGGATLIFQTELL 125
>FKBP2_MOUSE (P45878) FK506-binding protein 2 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (13 kDa FKBP) (FKBP-13) Length = 140 Score = 63.5 bits (153), Expect = 4e-10 Identities = 36/95 (37%), Positives = 53/95 (55%) Frame = +3 Query: 99 KPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIKGWDEGVMDMQLGE 278 K KG + +H TG +DG + + P QPF F++G G VIKGWD+G++ M GE Sbjct: 43 KSRKGDVLHMHYTGKLEDGTE----FDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGE 98 Query: 279 VARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVL 383 +L + YG G+P I + L+FE+E+L Sbjct: 99 KRKLVIPSELGYGERGAPP-KIPGGATLVFEVELL 132
>FKBP2_HUMAN (P26885) FK506-binding protein 2 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (13 kDa FKBP) (FKBP-13) Length = 142 Score = 63.5 bits (153), Expect = 4e-10 Identities = 36/95 (37%), Positives = 53/95 (55%) Frame = +3 Query: 99 KPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIKGWDEGVMDMQLGE 278 K KG + +H TG +DG + + P QPF F++G G VIKGWD+G++ M GE Sbjct: 45 KSRKGDVLHMHYTGKLEDGTE----FDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGE 100 Query: 279 VARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVL 383 +L + YG G+P I + L+FE+E+L Sbjct: 101 KRKLVIPSELGYGERGAPP-KIPGGATLVFEVELL 134
>FKBPH_SCHPO (Q10175) Probable peptidyl-prolyl cis-trans isomerase C27F1.06c (EC| 5.2.1.8) (PPIase) (Rotamase) Length = 362 Score = 63.2 bits (152), Expect = 5e-10 Identities = 38/113 (33%), Positives = 63/113 (55%) Frame = +3 Query: 48 DGKMGIQKEILRAGTGPKPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLG 227 +G + +Q ++ G GP + ++V++ G +G + K + K PF FN+GL Sbjct: 257 EGNVTVQDKV--KGDGPAAKRKKRVSMRYIGRLTNGKVFDKNITGK-----PFTFNLGLE 309 Query: 228 SVIKGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVLS 386 VIKGWD G++ MQ+G + AYGS P GI NS+L+F++++L+ Sbjct: 310 EVIKGWDVGIVGMQVGGERTIHIPAAMAYGSKRLP--GIPANSDLVFDVKLLA 360
>FKBP3_CANAL (Q59VR3) FK506-binding protein 3 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) Length = 426 Score = 63.2 bits (152), Expect = 5e-10 Identities = 42/111 (37%), Positives = 57/111 (51%) Frame = +3 Query: 60 GIQKEILRAGTGPKPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIK 239 G+ E + G+G G KV + G K+G + K S K PF+F +G G IK Sbjct: 323 GVITEDRKIGSGATAKSGAKVGIRYIGKLKNGKVFDKNTSGK-----PFSFKLGKGECIK 377 Query: 240 GWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVLSAK 392 G+D GV M +G R+ P YGS P GI NSEL F+I+++S K Sbjct: 378 GFDLGVTGMAVGGERRVIIPPKMGYGSQALP--GIPANSELTFDIKLVSLK 426
>FKBP3_DEBHA (Q6BSE7) FK506-binding protein 3 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) Length = 437 Score = 62.8 bits (151), Expect = 6e-10 Identities = 41/111 (36%), Positives = 55/111 (49%) Frame = +3 Query: 60 GIQKEILRAGTGPKPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIK 239 G+ E + G G G KV + G K+G + K S K PF F +G G IK Sbjct: 334 GVVTEDRKTGKGQTAKSGNKVGIRYIGKLKNGKVFDKNTSGK-----PFVFGLGKGECIK 388 Query: 240 GWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVLSAK 392 G+D GV M +G R+ P YGS P G+ NSEL F+I+++S K Sbjct: 389 GFDLGVAGMAVGGERRVVIPPKMGYGSQALP--GLPANSELTFDIKLVSIK 437
>FKBA_ECOLI (P45523) FKBP-type peptidyl-prolyl cis-trans isomerase fkpA| precursor (EC 5.2.1.8) (PPIase) (Rotamase) Length = 270 Score = 62.8 bits (151), Expect = 6e-10 Identities = 40/111 (36%), Positives = 60/111 (54%) Frame = +3 Query: 60 GIQKEILRAGTGPKPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIK 239 G+ +++ AG G P V V+ G DG K+F ++ G+ P +F L VI Sbjct: 147 GLVYQVVEAGKGEAPKDSDTVVVNYKGTLIDG---KEFDNSYTRGE-PLSFR--LDGVIP 200 Query: 240 GWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVLSAK 392 GW EG+ +++ G +L P+ AYG G P GI PNS L+F++E+L K Sbjct: 201 GWTEGLKNIKKGGKIKLVIPPELAYGKAGVP--GIPPNSTLVFDVELLDVK 249
>FKBA_ECOL6 (P65764) FKBP-type peptidyl-prolyl cis-trans isomerase fkpA| precursor (EC 5.2.1.8) (PPIase) (Rotamase) Length = 270 Score = 62.8 bits (151), Expect = 6e-10 Identities = 40/111 (36%), Positives = 60/111 (54%) Frame = +3 Query: 60 GIQKEILRAGTGPKPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIK 239 G+ +++ AG G P V V+ G DG K+F ++ G+ P +F L VI Sbjct: 147 GLVYQVVEAGKGEAPKDSDTVVVNYKGTLIDG---KEFDNSYTRGE-PLSFR--LDGVIP 200 Query: 240 GWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVLSAK 392 GW EG+ +++ G +L P+ AYG G P GI PNS L+F++E+L K Sbjct: 201 GWTEGLKNIKKGGKIKLVIPPELAYGKAGVP--GIPPNSTLVFDVELLDVK 249
>FKBA_ECO57 (P65765) FKBP-type peptidyl-prolyl cis-trans isomerase fkpA| precursor (EC 5.2.1.8) (PPIase) (Rotamase) Length = 270 Score = 62.8 bits (151), Expect = 6e-10 Identities = 40/111 (36%), Positives = 60/111 (54%) Frame = +3 Query: 60 GIQKEILRAGTGPKPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIK 239 G+ +++ AG G P V V+ G DG K+F ++ G+ P +F L VI Sbjct: 147 GLVYQVVEAGKGEAPKDSDTVVVNYKGTLIDG---KEFDNSYTRGE-PLSFR--LDGVIP 200 Query: 240 GWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVLSAK 392 GW EG+ +++ G +L P+ AYG G P GI PNS L+F++E+L K Sbjct: 201 GWTEGLKNIKKGGKIKLVIPPELAYGKAGVP--GIPPNSTLVFDVELLDVK 249
>FKBP2_GIBZE (Q4IN00) FK506-binding protein 2 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) Length = 195 Score = 62.8 bits (151), Expect = 6e-10 Identities = 40/98 (40%), Positives = 54/98 (55%), Gaps = 3/98 (3%) Frame = +3 Query: 99 KPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIKGWDEGVMDMQLGE 278 K KG V +H G KD K+F ++ D G P +F +G G VIKGWDEG++DM +GE Sbjct: 35 KTQKGDGVHMHYRGTLKDS--GKQFDASYDRGT-PLSFKVGAGQVIKGWDEGLLDMCIGE 91 Query: 279 VARLKCTPDYAYGS---GGSPAWGIQPNSELIFEIEVL 383 L P++ YG G PA S L+FE E++ Sbjct: 92 KRVLTIPPEFGYGQRAIGPIPA-----GSTLVFETELV 124
>FKB1B_EMENI (Q5AXD5) FK506-binding protein 1B (EC 5.2.1.8) (FKBP)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rapamycin-binding protein) Length = 120 Score = 62.8 bits (151), Expect = 6e-10 Identities = 43/111 (38%), Positives = 54/111 (48%), Gaps = 6/111 (5%) Frame = +3 Query: 60 GIQKEILRAGTG-PKPVKGQKVTVHCTGYGKDGDLSKK--FWSTK---DPGQQPFAFNIG 221 G+ K ILR G G P G V + TGY D + F T+ G+ P IG Sbjct: 6 GVTKTILRPGNGRDSPHTGDTVIIDYTGYLYDDTRGENEYFMGTQFDTSQGRGPLKTEIG 65 Query: 222 LGSVIKGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEI 374 +G VI GWD+GV M LGE A L + D YG G P I P+S L+ + Sbjct: 66 VGKVILGWDKGVQQMTLGEKAILTISSDNGYGKRGFPGL-IPPDSGLVLYV 115
>MIP_COXBU (P51752) Peptidyl-prolyl cis-trans isomerase Mip precursor (EC| 5.2.1.8) (PPIase) (Rotamase) (Macrophage infectivity potentiator) Length = 230 Score = 62.8 bits (151), Expect = 6e-10 Identities = 38/111 (34%), Positives = 56/111 (50%) Frame = +3 Query: 60 GIQKEILRAGTGPKPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIK 239 G+Q ++L+AG G P +VTV+ G +G + + P P L SVIK Sbjct: 125 GLQYKVLQAGQGQSPTLNDEVTVNYEGRLINGTVFDSSYKRGQPATFP------LKSVIK 178 Query: 240 GWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVLSAK 392 GW E + M+ G + + P AYG G+P I PN LIF++ ++S K Sbjct: 179 GWQEALTRMKPGAIWEIYVPPQLAYGEQGAPG-VIGPNEALIFKVNLISVK 228
>FKBP2_ASPOR (Q2UPT7) FK506-binding protein 2 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) Length = 134 Score = 62.4 bits (150), Expect = 8e-10 Identities = 40/99 (40%), Positives = 50/99 (50%), Gaps = 4/99 (4%) Frame = +3 Query: 99 KPVKGQKVTVHCTGY----GKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIKGWDEGVMDM 266 K VKG V +H G G + D S K P F +G G VIKGWDEG++DM Sbjct: 35 KTVKGDTVQMHYKGTLQSDGSEFDSSYK-------RNSPLKFKVGSGMVIKGWDEGLLDM 87 Query: 267 QLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVL 383 +GE L P+Y YGS G I + LIFE E++ Sbjct: 88 CIGEKRTLTIPPEYGYGSRG--VGPIPGGATLIFETELV 124
>FKBP4_SCHPO (O74191) FK506-binding protein 39 kDa (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) Length = 361 Score = 62.4 bits (150), Expect = 8e-10 Identities = 39/110 (35%), Positives = 60/110 (54%) Frame = +3 Query: 54 KMGIQKEILRAGTGPKPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSV 233 K G+ ++ G+G G+KV + G ++G + K +TK +PFAF +G G V Sbjct: 256 KGGVVVTDVKTGSGASATNGKKVEMRYIGKLENGKVFDK--NTKG---KPFAFILGRGEV 310 Query: 234 IKGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVL 383 I+GWD GV MQ G ++ AYG+ P GI NS L+FE++++ Sbjct: 311 IRGWDVGVAGMQEGGERKITIPAPMAYGNQSIP--GIPKNSTLVFEVKLV 358
>MIP_LEGLO (P53605) Outer membrane protein MIP precursor (Macrophage| infectivity potentiator) (Peptidyl-prolyl cis-trans isomerase) (EC 5.2.1.8) (PPIase) (Rotamase) Length = 233 Score = 60.8 bits (146), Expect = 2e-09 Identities = 46/113 (40%), Positives = 58/113 (51%), Gaps = 2/113 (1%) Frame = +3 Query: 60 GIQKEILRAGTGPKPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIK 239 G+Q +I+ AGTG KP K VTV TG DG + F ST+ G +P F + VI Sbjct: 127 GLQYKIIDAGTGAKPGKSDTVTVEYTGTLIDGTV---FDSTEKAG-KPATFQV--SQVIP 180 Query: 240 GWDEGVMDMQLGEVARLKCTPDYAYG--SGGSPAWGIQPNSELIFEIEVLSAK 392 GW E + M G + D AYG S G P I PN LIF+I ++S K Sbjct: 181 GWTEALQLMPAGSTWEVFVPADLAYGPRSVGGP---IGPNETLIFKIHLISVK 230
>FKBP7_MOUSE (O54998) FK506-binding protein 7 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (FKBP-23) Length = 218 Score = 60.1 bits (144), Expect = 4e-09 Identities = 38/92 (41%), Positives = 49/92 (53%), Gaps = 1/92 (1%) Frame = +3 Query: 108 KGQKVTVHCTGY-GKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIKGWDEGVMDMQLGEVA 284 KG + H GY KDG SK + S P F +G+G VIKG D +MDM GE Sbjct: 48 KGDLLNAHYDGYLAKDG--SKFYCSRTQDEGHPKWFVLGVGHVIKGLDIAMMDMCPGEKR 105 Query: 285 RLKCTPDYAYGSGGSPAWGIQPNSELIFEIEV 380 ++ P +AYG G I PN+ L+FEIE+ Sbjct: 106 KVIIPPSFAYGKEGYAEGKIPPNATLMFEIEL 137
>FKB15_VICFA (Q41649) FK506-binding protein 2 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (15 kDa FKBP) (FKBP-15) Length = 151 Score = 59.7 bits (143), Expect = 5e-09 Identities = 36/92 (39%), Positives = 48/92 (52%) Frame = +3 Query: 108 KGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIKGWDEGVMDMQLGEVAR 287 KG KV VH G DG + + + P F +G G VIKGWD+G++ M LGE + Sbjct: 48 KGDKVKVHYRGKLTDGTV----FDSSFERNSPIDFELGGGQVIKGWDQGLLGMCLGEKRK 103 Query: 288 LKCTPDYAYGSGGSPAWGIQPNSELIFEIEVL 383 LK YG GSP I + LIF+ E++ Sbjct: 104 LKIPAKLGYGEQGSPP-TIPGGATLIFDTELV 134
>FKBP2_CANGA (Q6FSC1) FK506-binding protein 2 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) Length = 136 Score = 59.7 bits (143), Expect = 5e-09 Identities = 38/110 (34%), Positives = 57/110 (51%) Frame = +3 Query: 54 KMGIQKEILRAGTGPKPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSV 233 K I K+I + K + G V+VH TG + K + + +P F +G G V Sbjct: 26 KFEITKKIPISKCKLKALPGDMVSVHYTGSLAENG---KVFDSSLRRNEPIQFKLGAGQV 82 Query: 234 IKGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVL 383 I GW++G+ M LGE L P+ AYGS G+ I PN+ L F++E++ Sbjct: 83 IAGWEQGITGMCLGEKRTLHIPPELAYGSRGA-GGVIPPNAVLDFDVELV 131
>FKB22_ARATH (Q38936) FK506-binding protein 2-2 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (15 kDa FKBP) (FKBP-15-2) Length = 163 Score = 58.9 bits (141), Expect = 9e-09 Identities = 34/93 (36%), Positives = 48/93 (51%) Frame = +3 Query: 108 KGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIKGWDEGVMDMQLGEVAR 287 KG + VH G DG + + DP F F +G G VIKGWD+G++ +GE + Sbjct: 51 KGDTIKVHYRGKLTDGTVFDSSFERGDP----FEFKLGSGQVIKGWDQGLLGACVGEKRK 106 Query: 288 LKCTPDYAYGSGGSPAWGIQPNSELIFEIEVLS 386 LK YG GSP I + LIF+ E+++ Sbjct: 107 LKIPAKLGYGEQGSPP-TIPGGATLIFDTELIA 138
>FKBA_AERHY (O08437) FKBP-type peptidyl-prolyl cis-trans isomerase fkpA| precursor (EC 5.2.1.8) (PPIase) (Rotamase) Length = 268 Score = 58.9 bits (141), Expect = 9e-09 Identities = 44/123 (35%), Positives = 61/123 (49%) Frame = +3 Query: 18 AAELWRGDAEDGKMGIQKEILRAGTGPKPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQ 197 AA + + + G+Q ++ + GTG KP V VH TG DG KF S+ D G Sbjct: 141 AANAKKEGVKSTESGLQYQVEKMGTGAKPKATDIVKVHYTGTLTDG---TKFDSSVDRG- 196 Query: 198 QPFAFNIGLGSVIKGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIE 377 +P F L VI GW EGV M +G + AYG G A I N+ L+F++E Sbjct: 197 EPATF--PLNQVIPGWTEGVQLMPVGSKFKFFLPSKLAYGEHG--AGSIPANAVLVFDVE 252 Query: 378 VLS 386 +L+ Sbjct: 253 LLA 255
>FKBP2_ASPFU (Q4WHX4) FK506-binding protein 2 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) Length = 134 Score = 58.9 bits (141), Expect = 9e-09 Identities = 37/96 (38%), Positives = 47/96 (48%), Gaps = 1/96 (1%) Frame = +3 Query: 99 KPVKGQKVTVHCTG-YGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIKGWDEGVMDMQLG 275 K KG V +H G DG + QP F +G G VIKGWDEG++DM +G Sbjct: 35 KTTKGDTVHMHYRGTLAADGSEFDSSYGRN----QPLKFKLGAGRVIKGWDEGLLDMCVG 90 Query: 276 EVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVL 383 E L P+Y YG G I + LIFE E++ Sbjct: 91 EKRTLTIPPEYGYGERG--IGPIPGGATLIFETELV 124
>FKB14_MOUSE (P59024) FK506-binding protein 14 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) Length = 211 Score = 58.2 bits (139), Expect = 2e-08 Identities = 39/96 (40%), Positives = 50/96 (52%), Gaps = 2/96 (2%) Frame = +3 Query: 111 GQKVTVHCTGY-GKDGDLSKKFWST-KDPGQQPFAFNIGLGSVIKGWDEGVMDMQLGEVA 284 G + VH GY KDG L F ST K QP F +G+ V+KGWD+G+ M +GE Sbjct: 45 GDLMLVHYEGYLEKDGSL---FHSTHKHNNGQPVWFTLGILEVLKGWDQGLKGMCVGEKR 101 Query: 285 RLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVLSAK 392 +L P YG G I P S LIF I++L + Sbjct: 102 KLTVPPALGYGKEGKGK--IPPESTLIFNIDLLEIR 135
>FKBY_HAEIN (P44760) Probable FKBP-type peptidyl-prolyl cis-trans isomerase (EC| 5.2.1.8) (PPIase) (Rotamase) Length = 241 Score = 58.2 bits (139), Expect = 2e-08 Identities = 46/122 (37%), Positives = 62/122 (50%), Gaps = 1/122 (0%) Frame = +3 Query: 21 AELWRG-DAEDGKMGIQKEILRAGTGPKPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQ 197 AE +G D + + G+ +I AG G V VH TG +G K F S+ + GQ Sbjct: 119 AEFAKGKDVKTTQSGLMYKIESAGKGDTIKSTDTVKVHYTGKLPNG---KVFDSSVERGQ 175 Query: 198 QPFAFNIGLGSVIKGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIE 377 P F L VIKGW EG+ ++ G + P+ YG G+ A I PNS LIF++E Sbjct: 176 -PVEFQ--LDQVIKGWTEGLQLVKKGGKIQFVIAPELGYGEQGAGA-SIPPNSTLIFDVE 231 Query: 378 VL 383 VL Sbjct: 232 VL 233
>FKBP2_KLULA (Q6CUZ8) FK506-binding protein 2 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) Length = 140 Score = 58.2 bits (139), Expect = 2e-08 Identities = 37/95 (38%), Positives = 54/95 (56%) Frame = +3 Query: 99 KPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIKGWDEGVMDMQLGE 278 K KG V+VH TG K D + F S+ + G P F +G VI GWD+G++ M +GE Sbjct: 39 KASKGDVVSVHYTG--KLRDSGEIFDSSYNRGV-PIQFKLGYSQVISGWDQGILGMCIGE 95 Query: 279 VARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVL 383 L + YGS G+ + I P+++LIFE E++ Sbjct: 96 GRTLHIPSELGYGSRGAGS-VIPPDADLIFETELV 129
>FKBP7_PONPY (Q5RET2) FK506-binding protein 7 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) Length = 222 Score = 57.4 bits (137), Expect = 3e-08 Identities = 37/92 (40%), Positives = 48/92 (52%), Gaps = 1/92 (1%) Frame = +3 Query: 108 KGQKVTVHCTGY-GKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIKGWDEGVMDMQLGEVA 284 KG + H GY KDG SK + S P F +G+G VIKG D + DM GE Sbjct: 52 KGDLLNAHYDGYLAKDG--SKFYCSRTQNEGHPKWFVLGVGQVIKGLDIAMTDMCPGEKR 109 Query: 285 RLKCTPDYAYGSGGSPAWGIQPNSELIFEIEV 380 ++ P +AYG G I P++ LIFEIE+ Sbjct: 110 KVVIPPSFAYGKEGYAEGKIPPDATLIFEIEL 141
>FKBP6_MOUSE (Q91XW8) FK506-binding protein 6 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) (36 kDa FK506-binding protein) (FKBP-36) (Immunophilin FKBP36) Length = 327 Score = 57.4 bits (137), Expect = 3e-08 Identities = 37/111 (33%), Positives = 58/111 (52%) Frame = +3 Query: 51 GKMGIQKEILRAGTGPKPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGS 230 G G+ K+I+R GTG V V +GY + D K + + + P +G Sbjct: 34 GDRGVLKDIIREGTGDTVTPDASVLVKYSGYLEHMD---KPFDSNCFRKTPRLMKLGEDI 90 Query: 231 VIKGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVL 383 + G + G++ M+ GE+AR P YAYG+ G P I PN+ ++FEIE++ Sbjct: 91 TLWGMELGLLSMRKGELARFLFKPAYAYGTLGCPPL-IPPNATVLFEIELI 140
>FKBP6_HUMAN (O75344) FK506-binding protein 6 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) (36 kDa FK506-binding protein) (FKBP-36) (Immunophilin FKBP36) Length = 327 Score = 57.4 bits (137), Expect = 3e-08 Identities = 40/120 (33%), Positives = 59/120 (49%), Gaps = 3/120 (2%) Frame = +3 Query: 51 GKMGIQKEILRAGTGPKPVKGQKVTVHCTGYGKDGDL---SKKFWSTKDPGQQPFAFNIG 221 G G+ K+++R G G V V +GY + D S F T P +G Sbjct: 34 GDRGVLKDVIREGAGDLVAPDASVLVKYSGYLEHMDRPFDSNYFRKT------PRLMKLG 87 Query: 222 LGSVIKGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVLSAK*CA 401 + G + G++ M+ GE+AR P+YAYG+ G P I PN+ ++FEIE+L CA Sbjct: 88 EDITLWGMELGLLSMRRGELARFLFKPNYAYGTLGCPPL-IPPNTTVLFEIELLDFLDCA 146
>FKB21_ARATH (Q38935) FK506-binding protein 2-1 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (15 kDa FKBP) (FKBP-15-1) Length = 153 Score = 57.4 bits (137), Expect = 3e-08 Identities = 33/93 (35%), Positives = 47/93 (50%) Frame = +3 Query: 108 KGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIKGWDEGVMDMQLGEVAR 287 KG K+ VH G DG + + DP F +G G VI GWD+G++ +GE + Sbjct: 51 KGDKIKVHYRGKLTDGTVFDSSFERGDP----IEFELGTGQVIPGWDQGLLGACVGEKRK 106 Query: 288 LKCTPDYAYGSGGSPAWGIQPNSELIFEIEVLS 386 LK YG GSP I + LIF+ E+++ Sbjct: 107 LKIPSKLGYGDNGSPP-KIPGGATLIFDTELVA 138
>MIP_LEGPN (P69059) Outer membrane protein MIP precursor (Macrophage| infectivity potentiator) (Peptidyl-prolyl cis-trans isomerase) (EC 5.2.1.8) (PPIase) (Rotamase) Length = 233 Score = 57.0 bits (136), Expect = 3e-08 Identities = 43/113 (38%), Positives = 56/113 (49%), Gaps = 2/113 (1%) Frame = +3 Query: 60 GIQKEILRAGTGPKPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIK 239 G+Q +++ AG G KP K VTV TG DG + F ST+ G +P F + VI Sbjct: 127 GLQYKVINAGNGVKPGKSDTVTVEYTGRLIDGTV---FDSTEKTG-KPATFQV--SQVIP 180 Query: 240 GWDEGVMDMQLGEVARLKCTPDYAYG--SGGSPAWGIQPNSELIFEIEVLSAK 392 GW E + M G + AYG S G P I PN LIF+I ++S K Sbjct: 181 GWTEALQLMPAGSTWEIYVPSGLAYGPRSVGGP---IGPNETLIFKIHLISVK 230
>MIP_LEGMI (P31106) Outer membrane protein MIP precursor (Macrophage| infectivity potentiator) (Peptidyl-prolyl cis-trans isomerase) (EC 5.2.1.8) (PPIase) (Rotamase) Length = 243 Score = 57.0 bits (136), Expect = 3e-08 Identities = 44/113 (38%), Positives = 55/113 (48%), Gaps = 2/113 (1%) Frame = +3 Query: 60 GIQKEILRAGTGPKPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIK 239 G+Q IL G G KP K VTV TG DG + F ST+ G +P F + VI Sbjct: 136 GLQYNILERGDGAKPTKDDVVTVEYTGKLIDGQV---FDSTEKTG-KPATFKV--SQVIP 189 Query: 240 GWDEGVMDMQLGEVARLKCTPDYAYG--SGGSPAWGIQPNSELIFEIEVLSAK 392 GW E + M G + + AYG S G P I PN LIF+I ++S K Sbjct: 190 GWTEALQLMPAGSTWEVYIPSNLAYGPRSVGGP---IGPNETLIFKIHLISVK 239
>FKBP4_CRYNE (Q5KIJ5) FK506-binding protein 4 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) Length = 405 Score = 56.6 bits (135), Expect = 5e-08 Identities = 37/109 (33%), Positives = 59/109 (54%) Frame = +3 Query: 60 GIQKEILRAGTGPKPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIK 239 G+ E ++ G GP G+++ + G +G K+F + +PF+F +G G VI+ Sbjct: 302 GLIIEDIKIGDGPVAKTGKRLGMRYIGKLTNG---KQF--DANTSGKPFSFVLGKGEVIR 356 Query: 240 GWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVLS 386 GWDEG+ M +G RL AYG+ P GI NS L F+++++S Sbjct: 357 GWDEGLAGMAVGGERRLTIPAALAYGNQKIP--GIPKNSTLKFDVKLVS 403
>FKB14_PONPY (Q5R941) FK506-binding protein 14 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) Length = 211 Score = 56.2 bits (134), Expect = 6e-08 Identities = 38/96 (39%), Positives = 49/96 (51%), Gaps = 2/96 (2%) Frame = +3 Query: 111 GQKVTVHCTGY-GKDGDLSKKFWST-KDPGQQPFAFNIGLGSVIKGWDEGVMDMQLGEVA 284 G + VH GY KDG L F ST K QP F +G+ +KGWD+G+ M +GE Sbjct: 45 GDLMLVHYEGYLEKDGSL---FHSTHKHNNGQPIWFTLGILEALKGWDQGLKGMCVGEKR 101 Query: 285 RLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVLSAK 392 +L P YG G I P S LIF I++L + Sbjct: 102 KLIIPPALGYGKEGKGK--IPPESTLIFNIDLLEIR 135
>FKB14_HUMAN (Q9NWM8) FK506-binding protein 14 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (22 kDa FK506-binding protein) (FKBP-22) Length = 211 Score = 56.2 bits (134), Expect = 6e-08 Identities = 38/96 (39%), Positives = 49/96 (51%), Gaps = 2/96 (2%) Frame = +3 Query: 111 GQKVTVHCTGY-GKDGDLSKKFWST-KDPGQQPFAFNIGLGSVIKGWDEGVMDMQLGEVA 284 G + VH GY KDG L F ST K QP F +G+ +KGWD+G+ M +GE Sbjct: 45 GDLMLVHYEGYLEKDGSL---FHSTHKHNNGQPIWFTLGILEALKGWDQGLKGMCVGEKR 101 Query: 285 RLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVLSAK 392 +L P YG G I P S LIF I++L + Sbjct: 102 KLIIPPALGYGKEGKGK--IPPESTLIFNIDLLEIR 135
>FKBP_STRCH (P28725) FK506-binding protein (Peptidyl-prolyl cis-trans| isomerase) (PPIase) (EC 5.2.1.8) (Rotamase) Length = 124 Score = 56.2 bits (134), Expect = 6e-08 Identities = 35/101 (34%), Positives = 47/101 (46%), Gaps = 1/101 (0%) Frame = +3 Query: 87 GTGPKPVKGQKVTVHCTGYG-KDGDLSKKFWSTKDPGQQPFAFNIGLGSVIKGWDEGVMD 263 G GP GQ V+VH G G+ W+ P Q F +G G VI GWD+GV Sbjct: 27 GDGPVAQAGQTVSVHYVGVAFSTGEEFDASWNRGTPLQ----FQLGAGQVISGWDQGVQG 82 Query: 264 MQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVLS 386 M++G L AYG G+ I P LIF ++++ Sbjct: 83 MKVGGRRELIIPAHLAYGDRGAGGGKIAPGETLIFVCDLVA 123
>FKBP2_ARATH (O22870) Probable FKBP-type peptidyl-prolyl cis-trans isomerase 2,| chloroplast precursor (EC 5.2.1.8) (PPIase) (Rotamase) Length = 223 Score = 55.8 bits (133), Expect = 8e-08 Identities = 36/110 (32%), Positives = 56/110 (50%), Gaps = 3/110 (2%) Frame = +3 Query: 60 GIQKEILRAGTGPKPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIK 239 G+Q + ++ G GP P G +V + G + F S+ + G P+ F +G G VIK Sbjct: 107 GLQYKDIKVGRGPSPPVGFQVAANYVAMVPSGQI---FDSSLEKGL-PYLFRVGSGQVIK 162 Query: 240 GWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWG---IQPNSELIFEIEV 380 G DEG++ M+ G RL A+ G A G + PNS +IF++ + Sbjct: 163 GLDEGILSMKAGGKRRLYIPGPLAFPKGLVSAPGRPRVAPNSPVIFDVSL 212
>MIP_LEGPH (Q5ZXE0) Outer membrane protein MIP precursor (Macrophage| infectivity potentiator) (Peptidyl-prolyl cis-trans isomerase) (EC 5.2.1.8) (PPIase) (Rotamase) Length = 233 Score = 55.8 bits (133), Expect = 8e-08 Identities = 42/113 (37%), Positives = 56/113 (49%), Gaps = 2/113 (1%) Frame = +3 Query: 60 GIQKEILRAGTGPKPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIK 239 G+Q +++ +G G KP K VTV TG DG + F ST+ G +P F + VI Sbjct: 127 GLQYKVINSGNGVKPGKSDTVTVEYTGRLIDGTV---FDSTEKTG-KPATFQV--SQVIP 180 Query: 240 GWDEGVMDMQLGEVARLKCTPDYAYG--SGGSPAWGIQPNSELIFEIEVLSAK 392 GW E + M G + AYG S G P I PN LIF+I ++S K Sbjct: 181 GWTEALQLMPAGSTWEIYVPSGLAYGPRSVGGP---IGPNETLIFKIHLISVK 230
>FKBP_CANAL (P28870) FK506-binding protein 1 (EC 5.2.1.8) (FKBP)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rapamycin-binding protein) Length = 124 Score = 54.3 bits (129), Expect = 2e-07 Identities = 42/118 (35%), Positives = 59/118 (50%), Gaps = 12/118 (10%) Frame = +3 Query: 66 QKEILRAGTGPKPVK-GQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIKG 242 Q EI++ G K G VT+H G +G K+F S++ G+ PF +G+G VIKG Sbjct: 7 QIEIVQEGDNTTFAKPGDTVTIHYDGKLTNG---KEFDSSRKRGK-PFTCTVGVGQVIKG 62 Query: 243 WDEGVMD-----------MQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVL 383 WD + + + G A L P+ AYG G P I PN L+FE+E+L Sbjct: 63 WDISLTNNYGKGGANLPKISKGTKAILTIPPNLAYGPRGIPPI-IGPNETLVFEVELL 119
>FKBB_SHIFL (P0A9L4) FKBP-type 22 kDa peptidyl-prolyl cis-trans isomerase (EC| 5.2.1.8) (PPIase) (Rotamase) (FKBP22) Length = 205 Score = 53.9 bits (128), Expect = 3e-07 Identities = 35/108 (32%), Positives = 52/108 (48%) Frame = +3 Query: 60 GIQKEILRAGTGPKPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIK 239 G+Q ++ G G P + +V VH TG DG + + +P + P + VI Sbjct: 102 GLQFRVINQGEGAIPARTDRVRVHYTGKLIDGTVFDSSVARGEPAEFP------VNGVIP 155 Query: 240 GWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVL 383 GW E + M +G L + AYG G+ A I P S L+FE+E+L Sbjct: 156 GWIEALTLMPVGSKWELTIPQELAYGERGAGA-SIPPFSTLVFEVELL 202
>FKBB_ECOLI (P0A9L3) FKBP-type 22 kDa peptidyl-prolyl cis-trans isomerase (EC| 5.2.1.8) (PPIase) (Rotamase) (FKBP22) Length = 205 Score = 53.9 bits (128), Expect = 3e-07 Identities = 35/108 (32%), Positives = 52/108 (48%) Frame = +3 Query: 60 GIQKEILRAGTGPKPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIK 239 G+Q ++ G G P + +V VH TG DG + + +P + P + VI Sbjct: 102 GLQFRVINQGEGAIPARTDRVRVHYTGKLIDGTVFDSSVARGEPAEFP------VNGVIP 155 Query: 240 GWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVL 383 GW E + M +G L + AYG G+ A I P S L+FE+E+L Sbjct: 156 GWIEALTLMPVGSKWELTIPQELAYGERGAGA-SIPPFSTLVFEVELL 202
>MIP_CHLMU (Q9PJK1) Peptidyl-prolyl cis-trans isomerase Mip precursor (EC| 5.2.1.8) (PPIase) (Rotamase) Length = 243 Score = 53.5 bits (127), Expect = 4e-07 Identities = 37/109 (33%), Positives = 53/109 (48%) Frame = +3 Query: 63 IQKEILRAGTGPKPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIKG 242 +Q I++ GTG +H TG +G + KDP P L VI G Sbjct: 136 LQYRIVKEGTGRVLTGKPNALLHYTGSFINGKVFDTSEKNKDPILLP------LTKVISG 189 Query: 243 WDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVLSA 389 + +G+ M+ GEV L PD AYG+ G + PNS LIFE++++ A Sbjct: 190 FSQGMQGMREGEVRVLYIHPDLAYGTSGQ----LPPNSLLIFEVKLIEA 234
>FKBA_BUCBP (Q89A61) FKBP-type peptidyl-prolyl cis-trans isomerase fkpA (EC| 5.2.1.8) (PPIase) (Rotamase) Length = 251 Score = 53.1 bits (126), Expect = 5e-07 Identities = 43/119 (36%), Positives = 62/119 (52%) Frame = +3 Query: 27 LWRGDAEDGKMGIQKEILRAGTGPKPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPF 206 L + DA G+ I + G+G +TVH G +G+ +F ++ GQ P Sbjct: 136 LKKKDARHTSSGLVFFIKKKGSGKFLHDSDVITVHYKGSLINGN---EFDNSYKRGQ-PL 191 Query: 207 AFNIGLGSVIKGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVL 383 +F+ L SVI GW EG+ ++ G + +L P AYG G P GI NS LIFEIE++ Sbjct: 192 SFS--LDSVIPGWIEGLKYIKKGGLIKLVIPPKLAYGETGVP--GIPGNSTLIFEIELI 246
>MIP_CHLTR (P26623) Peptidyl-prolyl cis-trans isomerase Mip precursor (EC| 5.2.1.8) (PPIase) (Rotamase) (27 kDa membrane protein) (Chl-Mip) Length = 243 Score = 52.4 bits (124), Expect = 9e-07 Identities = 36/109 (33%), Positives = 53/109 (48%) Frame = +3 Query: 63 IQKEILRAGTGPKPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIKG 242 +Q +++ GTG +H TG DG + K+P P L VI G Sbjct: 136 LQYRVVKEGTGRVLSGKPTALLHYTGSFIDGKVFDSSEKNKEPILLP------LTKVIPG 189 Query: 243 WDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVLSA 389 + +G+ M+ GEV L PD AYG+ G + PNS LIFE++++ A Sbjct: 190 FSQGMQGMKEGEVRVLYIHPDLAYGTAGQ----LPPNSLLIFEVKLIEA 234
>FKBP2_DEBHA (Q6BP84) FK506-binding protein 2 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) Length = 135 Score = 51.6 bits (122), Expect = 1e-06 Identities = 31/95 (32%), Positives = 48/95 (50%) Frame = +3 Query: 99 KPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIKGWDEGVMDMQLGE 278 K G ++VH G +DG + +S QP +F +G+G VI+GWD+G+ M +GE Sbjct: 36 KSKPGDLISVHYEGKLEDGTVFDSSYSRG----QPISFQLGIGQVIQGWDQGLTRMCIGE 91 Query: 279 VARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVL 383 +L AYG G I + L+F E++ Sbjct: 92 KRKLTIPSHLAYGDRG--VGPIPAKATLVFVAELV 124
>PAS1_ARATH (Q7DMA9) Peptidyl-prolyl isomerase PASTICCINO1 (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) Length = 635 Score = 47.4 bits (111), Expect = 3e-05 Identities = 29/94 (30%), Positives = 49/94 (52%) Frame = +3 Query: 102 PVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIKGWDEGVMDMQLGEV 281 P++ +++VH G + + + + S D QP F+ G G V +G++ M GE+ Sbjct: 288 PLQDSRLSVHYKGMLLNEEKTVFYDSKIDNNDQPLEFSSGEGLVPEGFEMCTRLMLPGEI 347 Query: 282 ARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVL 383 A + C PDYAY P G+ + + +EIE+L Sbjct: 348 ALVTCPPDYAYDKFPRPP-GVSEGAHVQWEIELL 380 Score = 46.2 bits (108), Expect = 6e-05 Identities = 35/109 (32%), Positives = 47/109 (43%), Gaps = 4/109 (3%) Frame = +3 Query: 69 KEILRAGTGPK-PVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIKGW 245 K ++R G G PV G +V HCT DG + + S P +G +I G Sbjct: 36 KAVVRPGGGDSSPVDGDQVIYHCTVRTLDGVVVESTRSESGGRGVPIRDVLGNSKMILGL 95 Query: 246 DEGVMDMQLGEVARLKCTPDYAYGSGGSPA---WGIQPNSELIFEIEVL 383 EG+ M GE+A K P+ Y P + EL FEIE+L Sbjct: 96 LEGIPTMHKGEIAMFKMKPEMHYAEIDCPVSAPENFPKDDELHFEIELL 144
>MIP_TRYCR (Q09734) Macrophage infectivity potentiator precursor| (Peptidyl-prolyl cis-trans isomerase) (EC 5.2.1.8) (PPIase) (Rotamase) Length = 196 Score = 47.0 bits (110), Expect = 4e-05 Identities = 41/119 (34%), Positives = 59/119 (49%), Gaps = 1/119 (0%) Frame = +3 Query: 39 DAEDGKMGIQKEILRAGTGPK-PVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFN 215 DA G+ + + G+G + P K VH TG +DG + F S+++ G+ P F Sbjct: 60 DAVKLPSGLVFQRIARGSGKRAPAIDDKCEVHYTGRLRDGTV---FDSSRERGK-PTTFR 115 Query: 216 IGLGSVIKGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVLSAK 392 VIKGW E + M+ G+ RL D AYG G I P S L F++E++S K Sbjct: 116 PN--EVIKGWTEALQLMREGDRWRLFIPYDLAYGVTGGGGM-IPPYSPLEFDVELISIK 171
>MIP_CHLPN (Q9Z7P3) Peptidyl-prolyl cis-trans isomerase Mip precursor (EC| 5.2.1.8) (PPIase) (Rotamase) Length = 258 Score = 46.2 bits (108), Expect = 6e-05 Identities = 35/110 (31%), Positives = 56/110 (50%), Gaps = 1/110 (0%) Frame = +3 Query: 63 IQKEILRAGTGPKPVKGQ-KVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIK 239 +Q +I++ G G K + G+ +H G +G + +S+ + +P + LG I Sbjct: 144 LQYKIIKEGAG-KAISGKPSALLHYKGSFINGQV----FSSSEGNNEPIL--LPLGQTIP 196 Query: 240 GWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVLSA 389 G+ G+ M+ GE L PD AYG+ G + PNS LIFEI ++ A Sbjct: 197 GFALGMQGMKEGETRVLYIHPDLAYGTAGQ----LPPNSLLIFEINLIQA 242
>FKBP7_HUMAN (Q9Y680) FK506-binding protein 7 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (FKBP-23) Length = 259 Score = 45.1 bits (105), Expect = 1e-04 Identities = 29/74 (39%), Positives = 37/74 (50%), Gaps = 1/74 (1%) Frame = +3 Query: 108 KGQKVTVHCTGY-GKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIKGWDEGVMDMQLGEVA 284 KG + H GY KDG SK + S P F +G+G VIKG D + DM GE Sbjct: 52 KGDLLNAHYDGYLAKDG--SKFYCSRTQNEGHPKWFVLGVGQVIKGLDIAMTDMCPGEKR 109 Query: 285 RLKCTPDYAYGSGG 326 ++ P +AYG G Sbjct: 110 KVVIPPSFAYGKEG 123
>FKBP_CORGL (P42458) Probable FK506-binding protein (Peptidyl-prolyl cis-trans| isomerase) (PPIase) (EC 5.2.1.8) (Rotamase) Length = 118 Score = 45.1 bits (105), Expect = 1e-04 Identities = 35/103 (33%), Positives = 51/103 (49%), Gaps = 2/103 (1%) Frame = +3 Query: 87 GTGPKPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIKGWDEGVMDM 266 G G + G +V VH G D + ++F S+ D GQ L +I GW EG+ M Sbjct: 25 GEGAEARPGGEVEVHYVGV--DFETGEEFDSSWDRGQTS---QFPLNGLIAGWQEGIPGM 79 Query: 267 QLGEVARLKCTPDYAYGSGGS--PAWGIQPNSELIFEIEVLSA 389 ++G +L P+ AYG GS P G L+F I+++SA Sbjct: 80 KVGGRRQLTIPPEAAYGPEGSGHPLSG----RTLVFIIDLISA 118
>FKB10_MOUSE (Q61576) FK506-binding protein 10 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (65 kDa FK506-binding protein) (FKBP65) (Immunophilin FKBP65) Length = 581 Score = 43.5 bits (101), Expect = 4e-04 Identities = 36/97 (37%), Positives = 50/97 (51%), Gaps = 1/97 (1%) Frame = +3 Query: 96 PKPVK-GQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIKGWDEGVMDMQL 272 P+ V+ G V H G +DG KKF S+ D A +G+G +I G D G+M M + Sbjct: 55 PREVQMGDFVRYHYNGTFEDG---KKFDSSYDRSTL-VAIVVGVGRLITGMDRGLMGMCV 110 Query: 273 GEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVL 383 E RL P YGS G A I P++ L F++ +L Sbjct: 111 NERRRLIVPPHLGYGSIG-VAGLIPPDATLYFDVVLL 146 Score = 41.2 bits (95), Expect = 0.002 Identities = 33/117 (28%), Positives = 51/117 (43%), Gaps = 2/117 (1%) Frame = +3 Query: 39 DAEDGKMGIQKEILRAGTG--PKPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAF 212 D + K +Q E L G + V G + H G DG L +S + Sbjct: 259 DVHNPKDTVQLETLELPQGCVRRAVAGDFMRYHYNGSLMDGTLFDSSYSRN----HTYNT 314 Query: 213 NIGLGSVIKGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVL 383 +G G +I G D+G+ +GE R+ P AYG G+ I ++ LIF++ V+ Sbjct: 315 YVGQGYIIPGMDQGLQGACIGERRRITVPPHLAYGENGT-GDKIPGSAVLIFDVHVI 370 Score = 40.8 bits (94), Expect = 0.003 Identities = 22/64 (34%), Positives = 36/64 (56%) Frame = +3 Query: 195 QQPFAFNIGLGSVIKGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEI 374 + P +G VI+G D G+ M +GE +L P A+G G A G+ ++ L+FE+ Sbjct: 422 EAPQEITLGANKVIEGLDRGLQGMCVGERRQLIVPPHLAHGENG--ARGVPGSAVLLFEV 479 Query: 375 EVLS 386 E++S Sbjct: 480 ELVS 483 Score = 35.4 bits (80), Expect = 0.11 Identities = 21/56 (37%), Positives = 31/56 (55%) Frame = +3 Query: 216 IGLGSVIKGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVL 383 IG G +IKG D+G++ M GE ++ P AYG G I P + L+F + +L Sbjct: 204 IGSGWLIKGMDQGLLGMCPGEKRKIIIPPFLAYGEKGY-GTVIPPQASLVFYVLLL 258
>FKB10_HUMAN (Q96AY3) FK506-binding protein 10 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (65 kDa FK506-binding protein) (FKBP65) (Immunophilin FKBP65) Length = 582 Score = 43.5 bits (101), Expect = 4e-04 Identities = 36/97 (37%), Positives = 50/97 (51%), Gaps = 1/97 (1%) Frame = +3 Query: 96 PKPVK-GQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIKGWDEGVMDMQL 272 P+ V+ G V H G +DG KKF S+ D A +G+G +I G D G+M M + Sbjct: 56 PREVQMGDFVRYHYNGTFEDG---KKFDSSYDRNTL-VAIVVGVGRLITGMDRGLMGMCV 111 Query: 273 GEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVL 383 E RL P YGS G A I P++ L F++ +L Sbjct: 112 NERRRLIVPPHLGYGSIGL-AGLIPPDATLYFDVVLL 147 Score = 39.3 bits (90), Expect = 0.007 Identities = 22/62 (35%), Positives = 35/62 (56%) Frame = +3 Query: 201 PFAFNIGLGSVIKGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEV 380 P +G VI+G D G+ M +GE +L P A+G G A G+ ++ L+FE+E+ Sbjct: 425 PQEATLGANKVIEGLDTGLQGMCVGERRQLIVPPHLAHGESG--ARGVPGSAVLLFEVEL 482 Query: 381 LS 386 +S Sbjct: 483 VS 484 Score = 38.9 bits (89), Expect = 0.010 Identities = 33/117 (28%), Positives = 49/117 (41%), Gaps = 2/117 (1%) Frame = +3 Query: 39 DAEDGKMGIQKEILRAGTG--PKPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAF 212 D + K +Q E L G + G + H G DG L +S + Sbjct: 260 DVHNPKDAVQLETLELPPGCVRRAGAGDFMRYHYNGSLMDGTLFDSSYSRN----HTYNT 315 Query: 213 NIGLGSVIKGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVL 383 IG G +I G D+G+ +GE R+ P AYG G+ I ++ LIF + V+ Sbjct: 316 YIGQGYIIPGMDQGLQGACMGERRRITIPPHLAYGENGT-GDKIPGSAVLIFNVHVI 371 Score = 34.7 bits (78), Expect = 0.18 Identities = 19/53 (35%), Positives = 29/53 (54%) Frame = +3 Query: 216 IGLGSVIKGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEI 374 +G G +IKG D+G++ M GE ++ P AYG G I P + L+F + Sbjct: 205 VGSGWLIKGMDQGLLGMCPGERRKIIIPPFLAYGEKGY-GTVIPPQASLVFHV 256
>FKBA_BUCAI (P57599) FKBP-type peptidyl-prolyl cis-trans isomerase fkpA (EC| 5.2.1.8) (PPIase) (Rotamase) Length = 241 Score = 43.1 bits (100), Expect = 5e-04 Identities = 35/101 (34%), Positives = 51/101 (50%) Frame = +3 Query: 81 RAGTGPKPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIKGWDEGVM 260 RAG G K+TVH G +G +F ++ G+ ++ L VI GW EG+ Sbjct: 143 RAGEGEALKDETKITVHYKGTLING---LEFDNSYKRGRP---VSLRLKDVILGWKEGLK 196 Query: 261 DMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVL 383 ++ G +L P+ AYG+ GI NS LIF+IE+L Sbjct: 197 YIKKGGKIKLVIPPNLAYGT--EEVNGIPANSTLIFDIELL 235
>FKBP4_ARATH (Q9SCY3) Probable FKBP-type peptidyl-prolyl cis-trans isomerase 4,| chloroplast precursor (EC 5.2.1.8) (PPIase) (Rotamase) Length = 217 Score = 42.0 bits (97), Expect = 0.001 Identities = 32/109 (29%), Positives = 49/109 (44%), Gaps = 10/109 (9%) Frame = +3 Query: 78 LRAGTGPKPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIKGWD--- 248 L G G + +G V +H T DG L + +P IG+G VI+G D Sbjct: 101 LDVGFGDEAPRGVLVNIHYTARFADGTLFDSSYKRA----RPLTMRIGVGKVIRGLDQGI 156 Query: 249 ---EGVMDMQLGEVARLKCTPDYAYGSGGSPAW----GIQPNSELIFEI 374 EGV M++G +L+ P AYG + + I N+ L+++I Sbjct: 157 LGGEGVPPMRVGGKRKLQIPPKLAYGPEPAGCFSGDCNIPGNATLLYDI 205
>FKBP8_MOUSE (O35465) 38 kDa FK506-binding protein homolog (FKBPR38)| (FK506-binding protein 8) (muFKBP38) Length = 355 Score = 42.0 bits (97), Expect = 0.001 Identities = 34/125 (27%), Positives = 56/125 (44%) Frame = +3 Query: 18 AAELWRGDAEDGKMGIQKEILRAGTGPKPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQ 197 A E W +G + ++ + +P+KGQ VTVH ++G T+ + Sbjct: 32 APEEWLDILGNGLLRMKTLVPCPKGSSRPLKGQVVTVHLQMSLENG--------TRVQEE 83 Query: 198 QPFAFNIGLGSVIKGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIE 377 AF +G VI+ D V M +GE A + Y YG G + I P++ L E+ Sbjct: 84 PELAFTLGDCDVIQALDLSVPLMDVGETAMVTADSKYCYGPQGRSPY-IPPHAALCLEVT 142 Query: 378 VLSAK 392 + +A+ Sbjct: 143 LKTAE 147
>FKBP8_HUMAN (Q14318) 38 kDa FK506-binding protein homolog (FKBPR38)| (FK506-binding protein 8) Length = 355 Score = 41.2 bits (95), Expect = 0.002 Identities = 30/97 (30%), Positives = 45/97 (46%) Frame = +3 Query: 99 KPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIKGWDEGVMDMQLGE 278 +PVKGQ VTVH ++G T+ + F +G VI+ D V M +GE Sbjct: 59 RPVKGQVVTVHLQTSLENG--------TRVQEEPELVFTLGDCDVIQALDLSVPLMDVGE 110 Query: 279 VARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVLSA 389 A + Y YG G + I P++ L E+ + +A Sbjct: 111 TAMVTADSKYCYGPQGRSPY-IPPHAALCLEVTLKTA 146
>FKBP9_MOUSE (Q9Z247) FK506-binding protein 9 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (FKBP65RS) Length = 570 Score = 40.8 bits (94), Expect = 0.003 Identities = 30/109 (27%), Positives = 49/109 (44%) Frame = +3 Query: 57 MGIQKEILRAGTGPKPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVI 236 + I+ +++ + G + H G DG L +S F IG G VI Sbjct: 260 ISIENKVVPENCERRSQSGDFLRYHYNGTLLDGTLFDSSYSRN----HTFDTYIGQGYVI 315 Query: 237 KGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVL 383 G DEG++ + +GE R+ P YG G + I ++ L+F+I V+ Sbjct: 316 PGMDEGLLGVCIGERRRIVVPPHLGYGEKGRGS--IPGSAVLVFDIHVI 362 Score = 37.0 bits (84), Expect = 0.037 Identities = 25/92 (27%), Positives = 41/92 (44%) Frame = +3 Query: 108 KGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIKGWDEGVMDMQLGEVAR 287 KG + H DG L W+ + + +G G V+ G D G+ +M +GE Sbjct: 388 KGDYLKYHYNASLLDGTLLDSTWNLG----KTYNIVLGSGQVVLGMDMGLREMCVGEKRT 443 Query: 288 LKCTPDYAYGSGGSPAWGIQPNSELIFEIEVL 383 + P YG G + ++ L+F+IE+L Sbjct: 444 VIIPPHLGYGEAGVDG-EVPGSAVLVFDIELL 474 Score = 34.7 bits (78), Expect = 0.18 Identities = 24/88 (27%), Positives = 41/88 (46%) Frame = +3 Query: 120 VTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIKGWDEGVMDMQLGEVARLKCT 299 V H G DG L + + + + +G+G +I G D+G++ M +GE + Sbjct: 169 VRYHYNGTFLDGTL----FDSSHNRMKTYDTYVGIGWLIPGMDKGLLGMCVGEKRIITVP 224 Query: 300 PDYAYGSGGSPAWGIQPNSELIFEIEVL 383 P AYG G I + L+F++ +L Sbjct: 225 PFLAYGEEGD-GKDIPGQASLVFDVALL 251
>FKBP9_RAT (Q66H94) FK506-binding protein 9 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) Length = 570 Score = 40.4 bits (93), Expect = 0.003 Identities = 29/109 (26%), Positives = 49/109 (44%) Frame = +3 Query: 57 MGIQKEILRAGTGPKPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVI 236 + ++ +++ + G + H G DG L +S F IG G VI Sbjct: 260 ISVENKVVPESCERRSQSGDFLRYHYNGTLLDGTLFDSSYSRN----HTFDTYIGQGYVI 315 Query: 237 KGWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVL 383 G DEG++ + +GE R+ P YG G + I ++ L+F+I V+ Sbjct: 316 PGMDEGLLGVCIGERRRIVVPPHLGYGEEGRGS--IPGSAVLVFDIHVI 362 Score = 37.7 bits (86), Expect = 0.022 Identities = 25/92 (27%), Positives = 41/92 (44%) Frame = +3 Query: 108 KGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIKGWDEGVMDMQLGEVAR 287 KG + H DG L W+ + + +G G V+ G D G+ +M +GE Sbjct: 388 KGDYLKYHYNASLLDGTLLDSTWNLG----KTYNIVLGFGQVVLGMDMGLREMCVGEKRT 443 Query: 288 LKCTPDYAYGSGGSPAWGIQPNSELIFEIEVL 383 + P YG G + ++ L+F+IE+L Sbjct: 444 VIIPPHLGYGEAGVDG-EVPGSAVLVFDIELL 474 Score = 34.7 bits (78), Expect = 0.18 Identities = 24/88 (27%), Positives = 41/88 (46%) Frame = +3 Query: 120 VTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIKGWDEGVMDMQLGEVARLKCT 299 V H G DG L + + + + +G+G +I G D+G++ M +GE + Sbjct: 169 VRYHYNGTFLDGTL----FDSSHNRMKTYDTYVGIGWLIPGMDKGLLGMCVGEKRIITIP 224 Query: 300 PDYAYGSGGSPAWGIQPNSELIFEIEVL 383 P AYG G I + L+F++ +L Sbjct: 225 PFLAYGEEGD-GKDIPGQASLVFDVALL 251
>FKBP9_HUMAN (O95302) FK506-binding protein 9 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) Length = 570 Score = 40.0 bits (92), Expect = 0.004 Identities = 29/91 (31%), Positives = 42/91 (46%) Frame = +3 Query: 111 GQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIKGWDEGVMDMQLGEVARL 290 G + H G DG L +S + F IG G VI G DEG++ + +GE R+ Sbjct: 278 GDFLRYHYNGTLLDGTLFDSSYSRN----RTFDTYIGQGYVIPGMDEGLLGVCIGEKRRI 333 Query: 291 KCTPDYAYGSGGSPAWGIQPNSELIFEIEVL 383 P YG G I ++ L+F+I V+ Sbjct: 334 VVPPHLGYGEEG--RGNIPGSAVLVFDIHVI 362 Score = 37.0 bits (84), Expect = 0.037 Identities = 25/92 (27%), Positives = 41/92 (44%) Frame = +3 Query: 108 KGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIKGWDEGVMDMQLGEVAR 287 KG + H DG L W+ + + +G G V+ G D G+ +M +GE Sbjct: 388 KGDYLKYHYNASLLDGTLLDSTWNLG----KTYNIVLGSGQVVLGMDMGLREMCVGEKRT 443 Query: 288 LKCTPDYAYGSGGSPAWGIQPNSELIFEIEVL 383 + P YG G + ++ L+F+IE+L Sbjct: 444 VIIPPHLGYGEAGVDG-EVPGSAVLVFDIELL 474 Score = 35.0 bits (79), Expect = 0.14 Identities = 24/88 (27%), Positives = 41/88 (46%) Frame = +3 Query: 120 VTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIKGWDEGVMDMQLGEVARLKCT 299 V H G DG L + + + + +G+G +I G D+G++ M +GE + Sbjct: 169 VRYHYNGTFLDGTL----FDSSHNRMKTYDTYVGIGWLIPGMDKGLLGMCVGEKRIITIP 224 Query: 300 PDYAYGSGGSPAWGIQPNSELIFEIEVL 383 P AYG G I + L+F++ +L Sbjct: 225 PFLAYGEDGD-GKDIPGQASLVFDVALL 251
>FKBP_METTL (O52980) FKBP-type peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8)| (PPIase) (Rotamase) (MtFK) Length = 154 Score = 39.3 bits (90), Expect = 0.007 Identities = 23/80 (28%), Positives = 40/80 (50%), Gaps = 9/80 (11%) Frame = +3 Query: 108 KGQKVTVHCTGYGKDGDL---------SKKFWSTKDPGQQPFAFNIGLGSVIKGWDEGVM 260 KG K+ V G + GD+ + D +P F +G G +I+G++E V+ Sbjct: 7 KGVKIKVDYIGKLESGDVFDTSIEEVAKEAGIYAPDREYEPLEFVVGEGQLIQGFEEAVL 66 Query: 261 DMQLGEVARLKCTPDYAYGS 320 DM++G+ +K + AYG+ Sbjct: 67 DMEVGDEKTVKIPAEKAYGN 86
>FKBA_BUCAP (Q8K943) FKBP-type peptidyl-prolyl cis-trans isomerase fkpA (EC| 5.2.1.8) (PPIase) (Rotamase) Length = 252 Score = 38.1 bits (87), Expect = 0.017 Identities = 32/95 (33%), Positives = 46/95 (48%) Frame = +3 Query: 108 KGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIKGWDEGVMDMQLGEVAR 287 K ++TVH G +G +F S+ G+ + L VI GW EG+ ++ G + Sbjct: 164 KNAEITVHYKGSLINGT---EFDSSYKRGKP---ITLMLKDVILGWQEGLKYIKKGGKIK 217 Query: 288 LKCTPDYAYGSGGSPAWGIQPNSELIFEIEVLSAK 392 L P+ YGS I NS LIF+IE+L K Sbjct: 218 LIIPPNLGYGSNRINE--IPANSILIFDIELLDIK 250
>AIPL1_MOUSE (Q924K1) Aryl-hydrocarbon-interacting protein-like 1| Length = 328 Score = 36.6 bits (83), Expect = 0.049 Identities = 27/81 (33%), Positives = 40/81 (49%), Gaps = 2/81 (2%) Frame = +3 Query: 60 GIQKEILRAGTGPKP--VKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSV 233 G++K IL GTG P + G +VT H D + + +K GQ P + IG Sbjct: 11 GVKKTILHGGTGELPNFITGSRVTFHFRTMKCDEERTV-IDDSKQVGQ-PMSIIIGNMFK 68 Query: 234 IKGWDEGVMDMQLGEVARLKC 296 ++ W+ + M+LGEVA C Sbjct: 69 LEVWETLLTSMRLGEVAEFWC 89
>FKBP1_METJA (Q57726) Putative FKBP-type peptidyl-prolyl cis-trans isomerase| MJ0278 (EC 5.2.1.8) (PPIase) (Rotamase) Length = 157 Score = 35.8 bits (81), Expect = 0.083 Identities = 14/40 (35%), Positives = 25/40 (62%) Frame = +3 Query: 198 QPFAFNIGLGSVIKGWDEGVMDMQLGEVARLKCTPDYAYG 317 +P F +G G +I+G++E V+ M++GE + P+ YG Sbjct: 45 EPIGFIVGNGELIEGFEEAVIGMEVGEEKTVTIPPEKGYG 84
>AIPL1_RAT (Q9JLG9) Aryl-hydrocarbon-interacting protein-like 1| Length = 328 Score = 35.4 bits (80), Expect = 0.11 Identities = 28/83 (33%), Positives = 41/83 (49%), Gaps = 4/83 (4%) Frame = +3 Query: 60 GIQKEILRAGTGPKP--VKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSV 233 G++K IL GTG P + G +VT H D + + +K GQ NI +G++ Sbjct: 11 GVKKTILHGGTGELPNFITGSRVTFHFRTMKCDEERTV-IDDSKQVGQP---MNIIIGNM 66 Query: 234 IK--GWDEGVMDMQLGEVARLKC 296 K W+ + M+LGEVA C Sbjct: 67 FKLEVWETLLTSMRLGEVAEFWC 89
>FKB11_MOUSE (Q9D1M7) FK506-binding protein 11 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (19 kDa FK506-binding protein) (FKBP-19) Length = 201 Score = 35.0 bits (79), Expect = 0.14 Identities = 23/92 (25%), Positives = 43/92 (46%) Frame = +3 Query: 111 GQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIKGWDEGVMDMQLGEVARL 290 G + +H TG DG + + + P +G VI G ++ ++DM +GE R Sbjct: 57 GDTLHIHYTGSLVDGRIIDTSLT-----RDPLVIELGQKQVIPGLEQSLLDMCVGEKRRA 111 Query: 291 KCTPDYAYGSGGSPAWGIQPNSELIFEIEVLS 386 AYG G P I ++ + +++E+++ Sbjct: 112 VIPSHLAYGKRGYPP-SIPADAVVQYDVELIA 142
>FKBP2_METJA (Q58235) Putative FKBP-type peptidyl-prolyl cis-trans isomerase| MJ0825 (EC 5.2.1.8) (PPIase) (Rotamase) Length = 231 Score = 34.3 bits (77), Expect = 0.24 Identities = 27/92 (29%), Positives = 42/92 (45%), Gaps = 8/92 (8%) Frame = +3 Query: 108 KGQKVTVHCTGY--GKDGDLSKKFWSTKD----PGQ--QPFAFNIGLGSVIKGWDEGVMD 263 KG+ V + GY GK D + + + K+ P P A G G V+ G DE +++ Sbjct: 4 KGKMVKISYDGYVDGKLFDTTNEELAKKEGIYNPAMIYGPVAIFAGEGQVLPGLDEAILE 63 Query: 264 MQLGEVARLKCTPDYAYGSGGSPAWGIQPNSE 359 M +GE + P+ A+G + P SE Sbjct: 64 MDVGEEREVVLPPEKAFGKRDPSKIKLIPLSE 95
>FKB11_HUMAN (Q9NYL4) FK506-binding protein 11 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (19 kDa FK506-binding protein) (FKBP-19) Length = 201 Score = 34.3 bits (77), Expect = 0.24 Identities = 22/92 (23%), Positives = 43/92 (46%) Frame = +3 Query: 111 GQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIKGWDEGVMDMQLGEVARL 290 G + +H TG DG + + + P +G VI G ++ ++DM +GE R Sbjct: 57 GDTLHIHYTGSLVDGRIIDTSLT-----RDPLVIELGQKQVIPGLEQSLLDMCVGEKRRA 111 Query: 291 KCTPDYAYGSGGSPAWGIQPNSELIFEIEVLS 386 AYG G P + ++ + +++E+++ Sbjct: 112 IIPSHLAYGKRGFPP-SVPADAVVQYDVELIA 142
>IF122_HUMAN (Q9HBG6) Intraflagellar transport 122 homolog (WD-repeat protein| 10) Length = 1242 Score = 33.5 bits (75), Expect = 0.41 Identities = 19/51 (37%), Positives = 25/51 (49%), Gaps = 8/51 (15%) Frame = +3 Query: 87 GTGPKPVKGQKVTVHCTGYGKDG--------DLSKKFWSTKDPGQQPFAFN 215 GT +P+KG K TV+C Y KDG D S W++K G + N Sbjct: 43 GTLLQPLKGHKDTVYCVAYAKDGKRFASGSADKSVIIWTSKLEGILKYTHN 93
>FKBZ_PSEAE (P30417) Probable FKBP-type 25 kDa peptidyl-prolyl cis-trans| isomerase (EC 5.2.1.8) (PPIase) (Rotamase) Length = 227 Score = 33.5 bits (75), Expect = 0.41 Identities = 32/108 (29%), Positives = 45/108 (41%) Frame = +3 Query: 60 GIQKEILRAGTGPKPVKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIK 239 G+ LR G G +V V G DG + Q A L SVI+ Sbjct: 127 GVLVSELRRGQGNGIGAATQVHVRYRGLLADGQVFD---------QSESAEWFALDSVIE 177 Query: 240 GWDEGVMDMQLGEVARLKCTPDYAYGSGGSPAWGIQPNSELIFEIEVL 383 GW + M +G R+ AYG G+ I P++ L+FEI++L Sbjct: 178 GWRTALRAMPVGARWRVVIPSAQAYGHEGAGDL-IPPDAPLVFEIDLL 224
>SLYD_HELPY (O25748) FKBP-type peptidyl-prolyl cis-trans isomerase slyD (EC| 5.2.1.8) (PPIase) (Rotamase) Length = 185 Score = 33.1 bits (74), Expect = 0.54 Identities = 14/41 (34%), Positives = 23/41 (56%) Frame = +3 Query: 195 QQPFAFNIGLGSVIKGWDEGVMDMQLGEVARLKCTPDYAYG 317 ++P F IG +I G ++ V+ Q+GE + P+ AYG Sbjct: 34 KEPLEFIIGTNQIIAGLEKAVLKAQIGEWEEVVIAPEEAYG 74
>SLYD_HELPJ (Q9ZK89) FKBP-type peptidyl-prolyl cis-trans isomerase slyD (EC| 5.2.1.8) (PPIase) (Rotamase) Length = 185 Score = 33.1 bits (74), Expect = 0.54 Identities = 14/41 (34%), Positives = 23/41 (56%) Frame = +3 Query: 195 QQPFAFNIGLGSVIKGWDEGVMDMQLGEVARLKCTPDYAYG 317 ++P F IG +I G ++ V+ Q+GE + P+ AYG Sbjct: 34 KEPLEFIIGANQIIVGLEKAVLKAQIGEWEEIVIAPEEAYG 74
>FKBX_SHIFL (P0AEM3) FKBP-type 16 kDa peptidyl-prolyl cis-trans isomerase (EC| 5.2.1.8) (PPIase) (Rotamase) Length = 148 Score = 30.4 bits (67), Expect = 3.5 Identities = 19/66 (28%), Positives = 36/66 (54%) Frame = +3 Query: 120 VTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIKGWDEGVMDMQLGEVARLKCT 299 V VH T DG ++ ST++ G+ P F +G S+ +G ++ ++ +++G+ Sbjct: 10 VLVHFTLKLDDGTTAE---STRNNGK-PALFRLGDASLSEGLEQHLLGLKVGDKTTFSLE 65 Query: 300 PDYAYG 317 PD A+G Sbjct: 66 PDAAFG 71
>FKBX_ECOLI (P0AEM0) FKBP-type 16 kDa peptidyl-prolyl cis-trans isomerase (EC| 5.2.1.8) (PPIase) (Rotamase) Length = 148 Score = 30.4 bits (67), Expect = 3.5 Identities = 19/66 (28%), Positives = 36/66 (54%) Frame = +3 Query: 120 VTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIKGWDEGVMDMQLGEVARLKCT 299 V VH T DG ++ ST++ G+ P F +G S+ +G ++ ++ +++G+ Sbjct: 10 VLVHFTLKLDDGTTAE---STRNNGK-PALFRLGDASLSEGLEQHLLGLKVGDKTTFSLE 65 Query: 300 PDYAYG 317 PD A+G Sbjct: 66 PDAAFG 71
>FKBX_ECOL6 (P0AEM1) FKBP-type 16 kDa peptidyl-prolyl cis-trans isomerase (EC| 5.2.1.8) (PPIase) (Rotamase) Length = 148 Score = 30.4 bits (67), Expect = 3.5 Identities = 19/66 (28%), Positives = 36/66 (54%) Frame = +3 Query: 120 VTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIKGWDEGVMDMQLGEVARLKCT 299 V VH T DG ++ ST++ G+ P F +G S+ +G ++ ++ +++G+ Sbjct: 10 VLVHFTLKLDDGTTAE---STRNNGK-PALFRLGDASLSEGLEQHLLGLKVGDKTTFSLE 65 Query: 300 PDYAYG 317 PD A+G Sbjct: 66 PDAAFG 71
>FKBX_ECO57 (P0AEM2) FKBP-type 16 kDa peptidyl-prolyl cis-trans isomerase (EC| 5.2.1.8) (PPIase) (Rotamase) Length = 148 Score = 30.4 bits (67), Expect = 3.5 Identities = 19/66 (28%), Positives = 36/66 (54%) Frame = +3 Query: 120 VTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSVIKGWDEGVMDMQLGEVARLKCT 299 V VH T DG ++ ST++ G+ P F +G S+ +G ++ ++ +++G+ Sbjct: 10 VLVHFTLKLDDGTTAE---STRNNGK-PALFRLGDASLSEGLEQHLLGLKVGDKTTFSLE 65 Query: 300 PDYAYG 317 PD A+G Sbjct: 66 PDAAFG 71
>NDOC_PSEFL (O07825) Naphthalene 1,2-dioxygenase beta subunit (EC 1.14.12.12)| (Naphthalene 1,2-dioxygenase ISP beta) (Fragment) Length = 158 Score = 29.6 bits (65), Expect = 5.9 Identities = 17/44 (38%), Positives = 25/44 (56%), Gaps = 2/44 (4%) Frame = -2 Query: 371 LEYQLGV--WLNSPGWRATRSISVVWGALKTGDFTQLHVHNSLI 246 +E+QL W NSP R TR I+ V A+ D LHV ++++ Sbjct: 99 VEHQLDSQNWSNSPKLRFTRFITNVQAAMDVNDEDLLHVRSNVV 142
>LV2G_HUMAN (P01710) Ig lambda chain V-II region BO| Length = 111 Score = 29.6 bits (65), Expect = 5.9 Identities = 14/32 (43%), Positives = 17/32 (53%), Gaps = 1/32 (3%) Frame = +3 Query: 111 GQKVTVHCTGYGKD-GDLSKKFWSTKDPGQQP 203 GQ VT+ CTG D GD W + PG+ P Sbjct: 15 GQSVTISCTGTSSDVGDNKYVSWYQQHPGRAP 46
>AIP_MOUSE (O08915) AH receptor-interacting protein (AIP) (Aryl-hydrocarbon| receptor-interacting protein) Length = 330 Score = 29.3 bits (64), Expect = 7.8 Identities = 23/81 (28%), Positives = 36/81 (44%), Gaps = 2/81 (2%) Frame = +3 Query: 60 GIQKEILRAGTGPKP--VKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSV 233 GIQK +++ G G P G K T H D + S ++ G+ P +G Sbjct: 12 GIQKRVIQEGRGELPDFQDGTKATFHFRTLHSDNEGSV-IDDSRTRGK-PMELIVGKKFK 69 Query: 234 IKGWDEGVMDMQLGEVARLKC 296 + W+ V M+ GE+A+ C Sbjct: 70 LPVWETIVCTMREGEIAQFLC 90
>AIP_HUMAN (O00170) AH receptor-interacting protein (AIP) (Aryl-hydrocarbon| receptor-interacting protein) (Immunophilin homolog ARA9) (HBV-X-associated protein 2) Length = 330 Score = 29.3 bits (64), Expect = 7.8 Identities = 24/81 (29%), Positives = 35/81 (43%), Gaps = 2/81 (2%) Frame = +3 Query: 60 GIQKEILRAGTGPKP--VKGQKVTVHCTGYGKDGDLSKKFWSTKDPGQQPFAFNIGLGSV 233 GIQK +++ G G P G K T H D D ++ G+ P IG Sbjct: 12 GIQKRVIQEGRGELPDFQDGTKATFHYRTLHSD-DEGTVLDDSRARGK-PMELIIGKKFK 69 Query: 234 IKGWDEGVMDMQLGEVARLKC 296 + W+ V M+ GE+A+ C Sbjct: 70 LPVWETIVCTMREGEIAQFLC 90 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 80,974,402 Number of Sequences: 219361 Number of extensions: 1728797 Number of successful extensions: 4377 Number of sequences better than 10.0: 148 Number of HSP's better than 10.0 without gapping: 4161 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4279 length of database: 80,573,946 effective HSP length: 105 effective length of database: 57,541,041 effective search space used: 4488201198 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
