ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | basd21f18 |
|---|---|
| Clone Library Name | barley_pub |
>SAPKA_ORYSA (Q75H77) Serine/threonine-protein kinase SAPK10 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 10) Length = 362 Score = 276 bits (705), Expect = 2e-74 Identities = 135/137 (98%), Positives = 136/137 (99%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQL+SGVSYCHSM Sbjct: 77 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLISGVSYCHSM 136 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD Sbjct: 137 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 196 Query: 367 GKIADVWSRGVTLYVML 417 GKIADVWS GVTLYVML Sbjct: 197 GKIADVWSCGVTLYVML 213
>SAPK9_ORYSA (Q75V57) Serine/threonine-protein kinase SAPK9 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 9) Length = 361 Score = 274 bits (700), Expect = 7e-74 Identities = 134/137 (97%), Positives = 136/137 (99%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PNIIRFKEVILTPTHLAIVMEYASGGELFERIC+AGRFSEDEARFFFQQL+SGVSYCHSM Sbjct: 76 PNIIRFKEVILTPTHLAIVMEYASGGELFERICSAGRFSEDEARFFFQQLISGVSYCHSM 135 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD Sbjct: 136 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 195 Query: 367 GKIADVWSRGVTLYVML 417 GKIADVWS GVTLYVML Sbjct: 196 GKIADVWSCGVTLYVML 212
>SAPK1_ORYSA (Q75LR7) Serine/threonine-protein kinase SAPK1 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 1) Length = 342 Score = 267 bits (682), Expect = 8e-72 Identities = 128/137 (93%), Positives = 133/137 (97%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PNIIRFKEV+LTPTHLAIVMEYA+GGELFERICNAGRFSEDEARFFFQQL+SGVSYCHSM Sbjct: 58 PNIIRFKEVVLTPTHLAIVMEYAAGGELFERICNAGRFSEDEARFFFQQLISGVSYCHSM 117 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 QVCHRDLKLENTLLDGS PRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVL +KEYD Sbjct: 118 QVCHRDLKLENTLLDGSVTPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLSRKEYD 177 Query: 367 GKIADVWSRGVTLYVML 417 GK+ADVWS GVTLYVML Sbjct: 178 GKVADVWSCGVTLYVML 194
>AAIP_WHEAT (Q02066) Abscisic acid-inducible protein kinase (EC 2.7.11.1)| (Fragment) Length = 332 Score = 266 bits (679), Expect = 2e-71 Identities = 127/137 (92%), Positives = 133/137 (97%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PNIIRFKEV+LTPTHLAIVMEYASGGELF+RICNAGRFSEDE RFFFQQL+SGVSYCHSM Sbjct: 48 PNIIRFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFFQQLISGVSYCHSM 107 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 QVCHRDLKLENTLLDGS APRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVL ++EYD Sbjct: 108 QVCHRDLKLENTLLDGSVAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLSRREYD 167 Query: 367 GKIADVWSRGVTLYVML 417 GK+ADVWS GVTLYVML Sbjct: 168 GKVADVWSCGVTLYVML 184
>SAPK2_ORYSA (Q84TC6) Serine/threonine-protein kinase SAPK2 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 2) Length = 339 Score = 265 bits (676), Expect = 4e-71 Identities = 125/137 (91%), Positives = 134/137 (97%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PNI+RFKEV+LTPTHLAIVMEYA+GGELFERIC+AGRFSEDEARFFFQQL+SGVSYCHSM Sbjct: 58 PNIVRFKEVVLTPTHLAIVMEYAAGGELFERICSAGRFSEDEARFFFQQLISGVSYCHSM 117 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 Q+CHRDLKLENTLLDGS APRLKICDFGYSKSS+LHSQPKSTVGTPAYIAPEVL +KEYD Sbjct: 118 QICHRDLKLENTLLDGSIAPRLKICDFGYSKSSLLHSQPKSTVGTPAYIAPEVLARKEYD 177 Query: 367 GKIADVWSRGVTLYVML 417 GK+ADVWS GVTLYVML Sbjct: 178 GKVADVWSCGVTLYVML 194
>SAPK8_ORYSA (Q7Y0B9) Serine/threonine-protein kinase SAPK8 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 8) Length = 371 Score = 261 bits (667), Expect = 5e-70 Identities = 128/137 (93%), Positives = 131/137 (95%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PNIIRFKEVILTPTHLAIVMEYASGGELFERIC RFSEDEAR+FFQQL+SGVSYCHSM Sbjct: 87 PNIIRFKEVILTPTHLAIVMEYASGGELFERICKNVRFSEDEARYFFQQLISGVSYCHSM 146 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 QVCHRDLKLENTLLDGS APRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD Sbjct: 147 QVCHRDLKLENTLLDGSPAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 206 Query: 367 GKIADVWSRGVTLYVML 417 GK ADVWS GVTLYVM+ Sbjct: 207 GKTADVWSCGVTLYVMV 223
>ASK1_ARATH (P43291) Serine/threonine-protein kinase ASK1 (EC 2.7.11.1)| Length = 363 Score = 257 bits (657), Expect = 7e-69 Identities = 121/137 (88%), Positives = 133/137 (97%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PNIIRFKEV+LTPTHLAI MEYA+GGELFERIC+AGRFSEDEAR+FFQQL+SGVSYCH+M Sbjct: 58 PNIIRFKEVVLTPTHLAIAMEYAAGGELFERICSAGRFSEDEARYFFQQLISGVSYCHAM 117 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 Q+CHRDLKLENTLLDGS APRLKICDFGYSKSS+LHS+PKSTVGTPAYIAPEVL ++EYD Sbjct: 118 QICHRDLKLENTLLDGSPAPRLKICDFGYSKSSLLHSRPKSTVGTPAYIAPEVLSRREYD 177 Query: 367 GKIADVWSRGVTLYVML 417 GK+ADVWS GVTLYVML Sbjct: 178 GKMADVWSCGVTLYVML 194
>SAPK7_ORYSA (Q7XQP4) Serine/threonine-protein kinase SAPK7 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 7) Length = 359 Score = 254 bits (650), Expect = 4e-68 Identities = 120/137 (87%), Positives = 131/137 (95%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PNIIRFKEV++TPTHLAIVMEYA+GGELF+RICNAGRFSEDEAR+FFQQL+ GVSYCH M Sbjct: 58 PNIIRFKEVVVTPTHLAIVMEYAAGGELFDRICNAGRFSEDEARYFFQQLICGVSYCHFM 117 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 Q+CHRDLKLENTLLDGS APRLKICDFGYSKSS+LHS+PKSTVGTPAYIAPEVL ++EYD Sbjct: 118 QICHRDLKLENTLLDGSPAPRLKICDFGYSKSSLLHSKPKSTVGTPAYIAPEVLSRREYD 177 Query: 367 GKIADVWSRGVTLYVML 417 GK ADVWS GVTLYVML Sbjct: 178 GKTADVWSCGVTLYVML 194
>SAPK6_ORYSA (Q6ZI44) Serine/threonine-protein kinase SAPK6 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 6) Length = 365 Score = 253 bits (647), Expect = 1e-67 Identities = 119/137 (86%), Positives = 132/137 (96%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PNIIRFKEV+LTPTHLAIVMEYA+GGELF+RIC+AGRFSEDE+R+FFQQL+ GVSYCH M Sbjct: 58 PNIIRFKEVVLTPTHLAIVMEYAAGGELFDRICSAGRFSEDESRYFFQQLICGVSYCHFM 117 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 Q+CHRDLKLENTLLDGS APRLKICDFGYSKSS+LHS+PKSTVGTPAYIAPEVL ++EYD Sbjct: 118 QICHRDLKLENTLLDGSPAPRLKICDFGYSKSSLLHSKPKSTVGTPAYIAPEVLSRREYD 177 Query: 367 GKIADVWSRGVTLYVML 417 GK+ADVWS GVTLYVML Sbjct: 178 GKMADVWSCGVTLYVML 194
>SAPK3_ORYSA (Q75V63) Serine/threonine-protein kinase SAPK3 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 3) (Protein kinase REK) Length = 334 Score = 252 bits (644), Expect = 2e-67 Identities = 118/137 (86%), Positives = 131/137 (95%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PNIIRFKEV LTPTHLAIVMEYA+GGELFE+IC AGRFSEDEAR+FFQQL+SGVSYCHS+ Sbjct: 59 PNIIRFKEVCLTPTHLAIVMEYAAGGELFEQICTAGRFSEDEARYFFQQLISGVSYCHSL 118 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 ++CHRDLKLENTLLDGS PR+KICDFGYSKS++LHS+PKSTVGTPAYIAPEVL +KEYD Sbjct: 119 EICHRDLKLENTLLDGSPTPRVKICDFGYSKSALLHSKPKSTVGTPAYIAPEVLSRKEYD 178 Query: 367 GKIADVWSRGVTLYVML 417 GK+ADVWS GVTLYVML Sbjct: 179 GKVADVWSCGVTLYVML 195
>ASK2_ARATH (P43292) Serine/threonine-protein kinase ASK2 (EC 2.7.11.1)| Length = 353 Score = 249 bits (635), Expect = 2e-66 Identities = 119/137 (86%), Positives = 128/137 (93%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PNIIRFKEVILTPTHLAIVMEYASGGELF+RIC AGRFSE EAR+FFQQL+ GV YCHS+ Sbjct: 58 PNIIRFKEVILTPTHLAIVMEYASGGELFDRICTAGRFSEAEARYFFQQLICGVDYCHSL 117 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 Q+CHRDLKLENTLLDGS AP LKICDFGYSKSS+LHS+PKSTVGTPAYIAPEVL ++EYD Sbjct: 118 QICHRDLKLENTLLDGSPAPLLKICDFGYSKSSILHSRPKSTVGTPAYIAPEVLSRREYD 177 Query: 367 GKIADVWSRGVTLYVML 417 GK ADVWS GVTLYVML Sbjct: 178 GKHADVWSCGVTLYVML 194
>SAPK5_ORYSA (Q7XKA8) Serine/threonine-protein kinase SAPK5 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 5) Length = 370 Score = 248 bits (632), Expect = 5e-66 Identities = 117/137 (85%), Positives = 129/137 (94%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PNIIRFKEV++T HLAIVMEYA+GGELFERIC AGRF EDEAR+FFQQL+ GVSYCH+M Sbjct: 58 PNIIRFKEVVVTGRHLAIVMEYAAGGELFERICEAGRFHEDEARYFFQQLVCGVSYCHAM 117 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 Q+CHRDLKLENTLLDGS APRLKICDFGYSKSS+LHS+PKSTVGTPAYIAPEVL ++EYD Sbjct: 118 QICHRDLKLENTLLDGSPAPRLKICDFGYSKSSLLHSRPKSTVGTPAYIAPEVLSRREYD 177 Query: 367 GKIADVWSRGVTLYVML 417 GK+ADVWS GVTLYVML Sbjct: 178 GKLADVWSCGVTLYVML 194
>SAPK4_ORYSA (Q5N942) Serine/threonine-protein kinase SAPK4 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 4) Length = 360 Score = 248 bits (632), Expect = 5e-66 Identities = 117/137 (85%), Positives = 128/137 (93%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PNIIRFKEVILTPTHL IVME+A+GGELF+RIC+ GRFSEDEAR+FFQQL+ GVSYCH M Sbjct: 58 PNIIRFKEVILTPTHLMIVMEFAAGGELFDRICDRGRFSEDEARYFFQQLICGVSYCHHM 117 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 Q+CHRDLKLEN LLDGS APRLKICDFGYSKSSVLHS+PKS VGTPAYIAPEVL ++EYD Sbjct: 118 QICHRDLKLENVLLDGSPAPRLKICDFGYSKSSVLHSRPKSAVGTPAYIAPEVLSRREYD 177 Query: 367 GKIADVWSRGVTLYVML 417 GK+ADVWS GVTLYVML Sbjct: 178 GKLADVWSCGVTLYVML 194
>CIPK1_ORYSA (Q6X4A2) CIPK-like protein 1 (EC 2.7.11.1) (OsCK1)| Length = 449 Score = 137 bits (344), Expect = 1e-32 Identities = 74/144 (51%), Positives = 93/144 (64%), Gaps = 7/144 (4%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PN++R EV+ + + IV+EY +GGELFE I GR E+EAR +FQQL++ V YCHS Sbjct: 78 PNVVRLFEVMGSKARIFIVLEYVTGGELFEIIATNGRLKEEEARKYFQQLINAVDYCHSR 137 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYS-------KSSVLHSQPKSTVGTPAYIAPEV 345 V HRDLKLEN LLD S LK+ DFG S +LH +T GTP Y+APEV Sbjct: 138 GVYHRDLKLENLLLDAS--GNLKVSDFGLSALTEQVKADGLLH----TTCGTPNYVAPEV 191 Query: 346 LLKKEYDGKIADVWSRGVTLYVML 417 + + YDG AD+WS GV LYV+L Sbjct: 192 IEDRGYDGAAADIWSCGVILYVLL 215
>KIN10_ARATH (Q38997) SNF1-related protein kinase catalytic alpha subunit KIN10| (EC 2.7.11.1) (AKIN10) (AKIN alpha2) Length = 535 Score = 133 bits (335), Expect = 1e-31 Identities = 73/137 (53%), Positives = 86/137 (62%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P+IIR EVI TPT + +VMEY + GELF+ I GR EDEAR FFQQ++SGV YCH Sbjct: 100 PHIIRLYEVIETPTDIYLVMEYVNSGELFDYIVEKGRLQEDEARNFFQQIISGVEYCHRN 159 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 V HRDLK EN LLD +KI DFG S K++ G+P Y APEV+ K Y Sbjct: 160 MVVHRDLKPENLLLDSKC--NVKIADFGLSNIMRDGHFLKTSCGSPNYAAPEVISGKLYA 217 Query: 367 GKIADVWSRGVTLYVML 417 G DVWS GV LY +L Sbjct: 218 GPEVDVWSCGVILYALL 234
>CIPK1_ARATH (Q8RWC9) CBL-interacting serine/threonine-protein kinase 1 (EC| 2.7.11.1) (SOS2-like protein kinase PKS13) (SNF1-related kinase 3.16) Length = 444 Score = 132 bits (333), Expect = 2e-31 Identities = 70/144 (48%), Positives = 93/144 (64%), Gaps = 7/144 (4%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P+I+R EV+ + T + +VME +GGELF+RI + G+ +E + R FQQL+ G+SYCHS Sbjct: 78 PHIVRLHEVLASKTKINMVMELVTGGELFDRIVSNGKLTETDGRKMFQQLIDGISYCHSK 137 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYS-------KSSVLHSQPKSTVGTPAYIAPEV 345 V HRDLKLEN LLD +KI DFG S +LH +T G+P Y+APEV Sbjct: 138 GVFHRDLKLENVLLDAK--GHIKITDFGLSALPQHFRDDGLLH----TTCGSPNYVAPEV 191 Query: 346 LLKKEYDGKIADVWSRGVTLYVML 417 L + YDG +D+WS GV LYV+L Sbjct: 192 LANRGYDGAASDIWSCGVILYVIL 215
>CPK24_ARATH (Q9LDI3) CBL-interacting serine/threonine-protein kinase 24 (EC| 2.7.11.1) (SNF1-related kinase 3.11) (SALT OVERLY SENSITIVE 2 protein) Length = 446 Score = 131 bits (330), Expect = 6e-31 Identities = 69/138 (50%), Positives = 93/138 (67%), Gaps = 1/138 (0%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PNI+R EV+ +P+ + IV+E+ +GGELF+RI + GR E E+R +FQQL+ V++CH Sbjct: 69 PNIVRLYEVLASPSKIYIVLEFVTGGELFDRIVHKGRLEESESRKYFQQLVDAVAHCHCK 128 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQ-PKSTVGTPAYIAPEVLLKKEY 363 V HRDLK EN LLD T LK+ DFG S + ++T GTP Y+APEVL + Y Sbjct: 129 GVYHRDLKPENLLLD--TNGNLKVSDFGLSALPQEGVELLRTTCGTPNYVAPEVLSGQGY 186 Query: 364 DGKIADVWSRGVTLYVML 417 DG AD+WS GV L+V+L Sbjct: 187 DGSAADIWSCGVILFVIL 204
>MARK1_HUMAN (Q9P0L2) Serine/threonine-protein kinase MARK1 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 1) Length = 795 Score = 130 bits (326), Expect = 2e-30 Identities = 66/137 (48%), Positives = 87/137 (63%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PNI++ EVI T L +VMEYASGGE+F+ + GR E EAR F+Q++S V YCH Sbjct: 117 PNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQK 176 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 + HRDLK EN LLDG +KI DFG+S + ++ + G+P Y APE+ K+YD Sbjct: 177 YIVHRDLKAENLLLDGDM--NIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKYD 234 Query: 367 GKIADVWSRGVTLYVML 417 G DVWS GV LY ++ Sbjct: 235 GPEVDVWSLGVILYTLV 251
>AAPK1_PONPY (Q5RDH5) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMPK alpha-1 chain) Length = 550 Score = 129 bits (325), Expect = 2e-30 Identities = 68/137 (49%), Positives = 85/137 (62%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P+II+ +VI TP+ + +VMEY SGGELF+ IC GR E E+R FQQ+LSGV YCH Sbjct: 76 PHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRH 135 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 V HRDLK EN LLD KI DFG S +++ G+P Y APEV+ + Y Sbjct: 136 MVVHRDLKPENVLLDAHM--NAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYA 193 Query: 367 GKIADVWSRGVTLYVML 417 G D+WS GV LY +L Sbjct: 194 GPEVDIWSSGVILYALL 210
>AAPK1_HUMAN (Q13131) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMPK alpha-1 chain) Length = 550 Score = 129 bits (325), Expect = 2e-30 Identities = 68/137 (49%), Positives = 85/137 (62%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P+II+ +VI TP+ + +VMEY SGGELF+ IC GR E E+R FQQ+LSGV YCH Sbjct: 76 PHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRH 135 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 V HRDLK EN LLD KI DFG S +++ G+P Y APEV+ + Y Sbjct: 136 MVVHRDLKPENVLLDAHM--NAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYA 193 Query: 367 GKIADVWSRGVTLYVML 417 G D+WS GV LY +L Sbjct: 194 GPEVDIWSSGVILYALL 210
>AAPK1_RAT (P54645) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMPK alpha-1 chain) Length = 548 Score = 129 bits (325), Expect = 2e-30 Identities = 68/137 (49%), Positives = 85/137 (62%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P+II+ +VI TP+ + +VMEY SGGELF+ IC GR E E+R FQQ+LSGV YCH Sbjct: 74 PHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRH 133 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 V HRDLK EN LLD KI DFG S +++ G+P Y APEV+ + Y Sbjct: 134 MVVHRDLKPENVLLDAHM--NAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYA 191 Query: 367 GKIADVWSRGVTLYVML 417 G D+WS GV LY +L Sbjct: 192 GPEVDIWSSGVILYALL 208
>AAPK1_MOUSE (Q5EG47) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMPK alpha-1 chain) Length = 548 Score = 129 bits (325), Expect = 2e-30 Identities = 68/137 (49%), Positives = 85/137 (62%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P+II+ +VI TP+ + +VMEY SGGELF+ IC GR E E+R FQQ+LSGV YCH Sbjct: 74 PHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRH 133 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 V HRDLK EN LLD KI DFG S +++ G+P Y APEV+ + Y Sbjct: 134 MVVHRDLKPENVLLDAHM--NAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYA 191 Query: 367 GKIADVWSRGVTLYVML 417 G D+WS GV LY +L Sbjct: 192 GPEVDIWSSGVILYALL 208
>MARK3_MOUSE (Q03141) MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1)| (MPK-10) (ELKL motif kinase 2) Length = 753 Score = 129 bits (324), Expect = 3e-30 Identities = 65/137 (47%), Positives = 87/137 (63%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PNI++ EVI T L ++MEYASGGE+F+ + GR E EAR F+Q++S V YCH Sbjct: 113 PNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQK 172 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 ++ HRDLK EN LLD +KI DFG+S + S+ + G+P Y APE+ K+YD Sbjct: 173 RIVHRDLKAENLLLDADM--NIKIADFGFSNEFTVGSKLDTFCGSPPYAAPELFQGKKYD 230 Query: 367 GKIADVWSRGVTLYVML 417 G DVWS GV LY ++ Sbjct: 231 GPEVDVWSLGVILYTLV 247
>MARK4_MOUSE (Q8CIP4) MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1)| Length = 752 Score = 129 bits (323), Expect = 4e-30 Identities = 65/137 (47%), Positives = 86/137 (62%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PNI++ EVI T L +VMEYAS GE+F+ + + GR E EAR F+Q++S V YCH Sbjct: 116 PNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQK 175 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 + HRDLK EN LLD +KI DFG+S L S+ + G+P Y APE+ K+YD Sbjct: 176 NIVHRDLKAENLLLDAEA--NIKIADFGFSNEFTLGSKLDTFCGSPPYAAPELFQGKKYD 233 Query: 367 GKIADVWSRGVTLYVML 417 G D+WS GV LY ++ Sbjct: 234 GPEVDIWSLGVILYTLV 250
>MARK4_HUMAN (Q96L34) MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase-like 1) Length = 752 Score = 129 bits (323), Expect = 4e-30 Identities = 65/137 (47%), Positives = 86/137 (62%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PNI++ EVI T L +VMEYAS GE+F+ + + GR E EAR F+Q++S V YCH Sbjct: 116 PNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQK 175 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 + HRDLK EN LLD +KI DFG+S L S+ + G+P Y APE+ K+YD Sbjct: 176 NIVHRDLKAENLLLDAEA--NIKIADFGFSNEFTLGSKLDTFCGSPPYAAPELFQGKKYD 233 Query: 367 GKIADVWSRGVTLYVML 417 G D+WS GV LY ++ Sbjct: 234 GPEVDIWSLGVILYTLV 250
>MARK3_RAT (Q8VHF0) MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1)| Length = 797 Score = 129 bits (323), Expect = 4e-30 Identities = 65/137 (47%), Positives = 87/137 (63%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PNI++ EVI T L ++MEYASGGE+F+ + GR E EAR F+Q++S V YCH Sbjct: 113 PNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQK 172 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 ++ HRDLK EN LLD +KI DFG+S + S+ + G+P Y APE+ K+YD Sbjct: 173 RIVHRDLKAENLLLDADM--NIKITDFGFSNEFTVGSKLDTFCGSPPYAAPELFQGKKYD 230 Query: 367 GKIADVWSRGVTLYVML 417 G DVWS GV LY ++ Sbjct: 231 GPEVDVWSLGVILYTLV 247
>CPK15_ARATH (P92937) CBL-interacting serine/threonine-protein kinase 15 (EC| 2.7.11.1) (Serine/threonine-protein kinase ATPK10) (SOS2-like protein kinase PKS3) (SOS-interacting protein 2) (SNF1-related kinase 3.1) Length = 421 Score = 128 bits (322), Expect = 5e-30 Identities = 71/140 (50%), Positives = 89/140 (63%), Gaps = 3/140 (2%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PNI+ EV+ T + + VME+ GGELF ++ + G+ ED AR +FQQL+ V +CHS Sbjct: 70 PNIVELHEVMATKSKIYFVMEHVKGGELFNKV-STGKLREDVARKYFQQLVRAVDFCHSR 128 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQP---KSTVGTPAYIAPEVLLKK 357 VCHRDLK EN LLD LKI DFG S S Q +T GTPAY+APEV+ + Sbjct: 129 GVCHRDLKPENLLLD--EHGNLKISDFGLSALSDSRRQDGLLHTTCGTPAYVAPEVISRN 186 Query: 358 EYDGKIADVWSRGVTLYVML 417 YDG ADVWS GV L+V+L Sbjct: 187 GYDGFKADVWSCGVILFVLL 206
>KIN11_ARATH (P92958) SNF1-related protein kinase catalytic alpha subunit KIN11| (EC 2.7.11.1) (AKIN11) (AKIN alpha1) Length = 512 Score = 127 bits (320), Expect = 8e-30 Identities = 71/137 (51%), Positives = 84/137 (61%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P+IIR EVI T + + +VMEY GELF+ I GR EDEAR FFQQ++SGV YCH Sbjct: 78 PHIIRQYEVIETTSDIYVVMEYVKSGELFDYIVEKGRLQEDEARNFFQQIISGVEYCHRN 137 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 V HRDLK EN LLD +KI DFG S K++ G+P Y APEV+ K Y Sbjct: 138 MVVHRDLKPENLLLDSRC--NIKIADFGLSNVMRDGHFLKTSCGSPNYAAPEVISGKLYA 195 Query: 367 GKIADVWSRGVTLYVML 417 G DVWS GV LY +L Sbjct: 196 GPEVDVWSCGVILYALL 212
>AAPK2_RAT (Q09137) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMPK alpha-2 chain) Length = 552 Score = 127 bits (320), Expect = 8e-30 Identities = 69/137 (50%), Positives = 83/137 (60%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P+II+ +VI TPT +VMEY SGGELF+ IC GR E EAR FQQ+LS V YCH Sbjct: 74 PHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEVEARRLFQQILSAVDYCHRH 133 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 V HRDLK EN LLD KI DFG S +++ G+P Y APEV+ + Y Sbjct: 134 MVVHRDLKPENVLLDAQM--NAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYA 191 Query: 367 GKIADVWSRGVTLYVML 417 G D+WS GV LY +L Sbjct: 192 GPEVDIWSCGVILYALL 208
>AAPK2_PIG (Q28948) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMPK alpha-2 chain) Length = 552 Score = 127 bits (320), Expect = 8e-30 Identities = 69/137 (50%), Positives = 83/137 (60%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P+II+ +VI TPT +VMEY SGGELF+ IC GR E EAR FQQ+LS V YCH Sbjct: 74 PHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHRH 133 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 V HRDLK EN LLD KI DFG S +++ G+P Y APEV+ + Y Sbjct: 134 MVVHRDLKPENVLLDAQM--NAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYA 191 Query: 367 GKIADVWSRGVTLYVML 417 G D+WS GV LY +L Sbjct: 192 GPEVDIWSCGVILYALL 208
>AAPK2_HUMAN (P54646) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMPK alpha-2 chain) Length = 552 Score = 127 bits (319), Expect = 1e-29 Identities = 69/137 (50%), Positives = 83/137 (60%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P+II+ +VI TPT +VMEY SGGELF+ IC GR E EAR FQQ+LS V YCH Sbjct: 74 PHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHRH 133 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 V HRDLK EN LLD KI DFG S +++ G+P Y APEV+ + Y Sbjct: 134 MVVHRDLKPENVLLDAHM--NAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYA 191 Query: 367 GKIADVWSRGVTLYVML 417 G D+WS GV LY +L Sbjct: 192 GPEVDIWSCGVILYALL 208
>CPK11_ARATH (O22932) CBL-interacting serine/threonine-protein kinase 11 (EC| 2.7.11.1) (SOS2-like protein kinase PKS5) (SOS-interacting protein 4) (SNF1-related kinase 3.22) Length = 435 Score = 127 bits (318), Expect = 1e-29 Identities = 67/144 (46%), Positives = 90/144 (62%), Gaps = 7/144 (4%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PNI++ EV+ T + + ME+ GGELF +I GR SED +R +FQQL+S V YCH+ Sbjct: 80 PNIVKLHEVMATKSKIFFAMEFVKGGELFNKISKHGRLSEDLSRRYFQQLISAVGYCHAR 139 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYS-------KSSVLHSQPKSTVGTPAYIAPEV 345 V HRDLK EN L+D + LK+ DFG S +LH + GTPAY+APE+ Sbjct: 140 GVYHRDLKPENLLIDEN--GNLKVSDFGLSALTDQIRPDGLLH----TLCGTPAYVAPEI 193 Query: 346 LLKKEYDGKIADVWSRGVTLYVML 417 L KK Y+G DVWS G+ L+V++ Sbjct: 194 LSKKGYEGAKVDVWSCGIVLFVLV 217
>AAPK2_PONPY (Q5RD00) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMPK alpha-2 chain) Length = 552 Score = 127 bits (318), Expect = 1e-29 Identities = 69/137 (50%), Positives = 83/137 (60%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P+II+ +VI TPT +VMEY SGGELF+ IC GR E EAR FQQ+LS V YCH Sbjct: 74 PHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHRH 133 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 V HRDLK EN LLD KI DFG S +++ G+P Y APEV+ + Y Sbjct: 134 MVVHRDLKPENVLLDAHM--NAKIADFGLSNIMSDGEFLRTSCGSPNYAAPEVISGRLYA 191 Query: 367 GKIADVWSRGVTLYVML 417 G D+WS GV LY +L Sbjct: 192 GPEVDIWSCGVILYALL 208
>MARK1_RAT (O08678) Serine/threonine-protein kinase MARK1 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 1) Length = 793 Score = 127 bits (318), Expect = 1e-29 Identities = 65/137 (47%), Positives = 86/137 (62%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PNI++ EVI T L +VMEYASGGE+F+ + GR E EAR F+Q++S V YCH Sbjct: 117 PNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQK 176 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 + HRDLK EN LLD +KI DFG+S + ++ + G+P Y APE+ K+YD Sbjct: 177 CIVHRDLKAENLLLDADM--NIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKYD 234 Query: 367 GKIADVWSRGVTLYVML 417 G DVWS GV LY ++ Sbjct: 235 GPEVDVWSLGVILYTLV 251
>MARK1_MOUSE (Q8VHJ5) Serine/threonine-protein kinase MARK1 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 1) (ELKL motif serine/threonine-protein kinase 3) Length = 795 Score = 127 bits (318), Expect = 1e-29 Identities = 65/137 (47%), Positives = 86/137 (62%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PNI++ EVI T L +VMEYASGGE+F+ + GR E EAR F+Q++S V YCH Sbjct: 117 PNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQK 176 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 + HRDLK EN LLD +KI DFG+S + ++ + G+P Y APE+ K+YD Sbjct: 177 CIVHRDLKAENLLLDADM--NIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKYD 234 Query: 367 GKIADVWSRGVTLYVML 417 G DVWS GV LY ++ Sbjct: 235 GPEVDVWSLGVILYTLV 251
>MARK2_RAT (O08679) Serine/threonine-protein kinase MARK2 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 2) (ELKL Motif Kinase) (EMK1) Length = 722 Score = 126 bits (317), Expect = 2e-29 Identities = 65/137 (47%), Positives = 85/137 (62%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PNI++ EVI T L +VMEYASGGE+F+ + GR E EAR F+Q++S V YCH Sbjct: 110 PNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQK 169 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 + HRDLK EN LLD +KI DFG+S ++ + G+P Y APE+ K+YD Sbjct: 170 FIVHRDLKAENLLLDADM--NIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYD 227 Query: 367 GKIADVWSRGVTLYVML 417 G DVWS GV LY ++ Sbjct: 228 GPEVDVWSLGVILYTLV 244
>MARK2_HUMAN (Q7KZI7) Serine/threonine-protein kinase MARK2 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 2) (ELKL motif kinase) (EMK1) (PAR1 homolog) Length = 788 Score = 126 bits (317), Expect = 2e-29 Identities = 65/137 (47%), Positives = 85/137 (62%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PNI++ EVI T L +VMEYASGGE+F+ + GR E EAR F+Q++S V YCH Sbjct: 110 PNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQK 169 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 + HRDLK EN LLD +KI DFG+S ++ + G+P Y APE+ K+YD Sbjct: 170 FIVHRDLKAENLLLDADM--NIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYD 227 Query: 367 GKIADVWSRGVTLYVML 417 G DVWS GV LY ++ Sbjct: 228 GPEVDVWSLGVILYTLV 244
>AAPK2_CAEEL (Q95ZQ4) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMP-activated kinase 2) Length = 626 Score = 126 bits (316), Expect = 2e-29 Identities = 68/137 (49%), Positives = 85/137 (62%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P+IIR +VI TP+ + ++ME+ SGGELF+ I GR EAR FFQQ++SGV YCH Sbjct: 145 PHIIRLYQVISTPSDIFMIMEHVSGGELFDYIVKHGRLKTAEARRFFQQIISGVDYCHRH 204 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 V HRDLK EN LLD +KI DFG S +++ G+P Y APEV+ K Y Sbjct: 205 MVVHRDLKPENLLLDEQN--NVKIADFGLSNIMTDGDFLRTSCGSPNYAAPEVISGKLYA 262 Query: 367 GKIADVWSRGVTLYVML 417 G DVWS GV LY +L Sbjct: 263 GPEVDVWSCGVILYALL 279
>SNF1_SCHPO (O74536) SNF1-like protein kinase ssp2 (EC 2.7.11.1)| Length = 576 Score = 125 bits (313), Expect = 5e-29 Identities = 67/137 (48%), Positives = 88/137 (64%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P+II+ +VI TPT + +V+EYA GGELF+ I R +EDE R FFQQ++ + YCH Sbjct: 92 PHIIKLYDVITTPTDIVMVIEYA-GGELFDYIVEKKRMTEDEGRRFFQQIICAIEYCHRH 150 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 ++ HRDLK EN LLD + +KI DFG S + K++ G+P Y APEV+ K Y Sbjct: 151 KIVHRDLKPENLLLDDNL--NVKIADFGLSNIMTDGNFLKTSCGSPNYAAPEVINGKLYA 208 Query: 367 GKIADVWSRGVTLYVML 417 G DVWS G+ LYVML Sbjct: 209 GPEVDVWSCGIVLYVML 225
>BRSK2_HUMAN (Q8IWQ3) BR serine/threonine-protein kinase 2 (EC 2.7.11.1)| (Serine/threonine-protein kinase 29) (SAD1B) Length = 736 Score = 121 bits (304), Expect = 6e-28 Identities = 58/137 (42%), Positives = 89/137 (64%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P++++ +V +L +V+E+ SGGELF+ + GR + EAR FF+Q++S + +CHS Sbjct: 76 PHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSH 135 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 +CHRDLK EN LLD ++I DFG + V S +++ G+P Y PEV+ ++YD Sbjct: 136 SICHRDLKPENLLLDEKN--NIRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYD 193 Query: 367 GKIADVWSRGVTLYVML 417 G+ ADVWS GV L+ +L Sbjct: 194 GRKADVWSCGVILFALL 210
>MARK2_MOUSE (Q05512) Serine/threonine-protein kinase MARK2 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 2) (ELKL Motif Kinase) (EMK1) Length = 776 Score = 120 bits (301), Expect = 1e-27 Identities = 63/137 (45%), Positives = 83/137 (60%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PNI++ EVI T L +VMEYASGGE+F+ + GR E EAR F+Q++ V YCH Sbjct: 110 PNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVLHVQYCHQK 169 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 + HRDLK EN LLD +KI DFG+S ++ + G+P Y APE+ K+ D Sbjct: 170 FIVHRDLKAENLLLDADM--NIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKID 227 Query: 367 GKIADVWSRGVTLYVML 417 G DVWS GV LY ++ Sbjct: 228 GPEVDVWSLGVILYTLV 244
>BRSK1_HUMAN (Q8TDC3) BR serine/threonine-protein kinase 1 (EC 2.7.11.1) (SAD1| kinase) (SAD1A) Length = 794 Score = 120 bits (301), Expect = 1e-27 Identities = 57/137 (41%), Positives = 89/137 (64%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P++++ +V +L +V+E+ SGGELF+ + GR + EAR FF+Q++S + +CHS Sbjct: 107 PHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALDFCHSY 166 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 +CHRDLK EN LLD ++I DFG + V S +++ G+P Y PEV+ ++YD Sbjct: 167 SICHRDLKPENLLLDEKN--NIRIADFGMASLQVGDSLLETSCGSPHYACPEVIKGEKYD 224 Query: 367 GKIADVWSRGVTLYVML 417 G+ AD+WS GV L+ +L Sbjct: 225 GRRADMWSCGVILFALL 241
>SN1L1_MOUSE (Q60670) Serine/threonine-protein kinase SNF1-like kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase SNF1LK) (HRT-20) (Myocardial SNF1-like kinase) Length = 779 Score = 119 bits (299), Expect = 2e-27 Identities = 66/138 (47%), Positives = 88/138 (63%), Gaps = 1/138 (0%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PNII+ +V+ T L IV E+A GE+F+ + + G SE+EAR F Q+LS V YCH+ Sbjct: 84 PNIIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARQKFWQILSAVEYCHNH 143 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKST-VGTPAYIAPEVLLKKEY 363 + HRDLK EN LLD + +K+ DFG+ + +P ST VG+P Y APEV KEY Sbjct: 144 HIVHRDLKTENLLLDSNM--DIKLADFGFG-NFYKPGEPLSTCVGSPPYAAPEVFEGKEY 200 Query: 364 DGKIADVWSRGVTLYVML 417 +G DVWS GV LYV++ Sbjct: 201 EGPQLDVWSLGVVLYVLV 218
>SN1L1_RAT (Q9R1U5) Serine/threonine-protein kinase SNF1-like kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase SNF1LK) (Salt-inducible protein kinase) (Protein kinase KID2) Length = 776 Score = 119 bits (299), Expect = 2e-27 Identities = 65/138 (47%), Positives = 88/138 (63%), Gaps = 1/138 (0%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PNII+ +V+ T L IV E+A GE+F+ + + G SE+EAR F Q+LS V YCH+ Sbjct: 84 PNIIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQILSAVEYCHNH 143 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKST-VGTPAYIAPEVLLKKEY 363 + HRDLK EN LLDG+ +K+ DFG+ + +P ST G+P Y APEV KEY Sbjct: 144 HIVHRDLKTENLLLDGNM--DIKLADFGFG-NFYKPGEPLSTWCGSPPYAAPEVFEGKEY 200 Query: 364 DGKIADVWSRGVTLYVML 417 +G D+WS GV LYV++ Sbjct: 201 EGPQLDIWSLGVVLYVLV 218
>KKK1_YEAST (P34244) Probable serine/threonine-protein kinase YKL101W (EC| 2.7.11.1) Length = 1518 Score = 119 bits (299), Expect = 2e-27 Identities = 57/136 (41%), Positives = 87/136 (63%) Frame = +1 Query: 10 NIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSMQ 189 N++ EV + L +V+EY GGELF+ + + G+ E EA +F+Q++ GVSYCHS Sbjct: 175 NVMALFEVWENKSELYLVLEYVDGGELFDYLVSKGKLPEREAIHYFKQIVEGVSYCHSFN 234 Query: 190 VCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYDG 369 +CHRDLK EN LLD R+KI DFG + + + K++ G+P Y +PE+++ + Y G Sbjct: 235 ICHRDLKPENLLLDKKNR-RIKIADFGMAALELPNKLLKTSCGSPHYASPEIVMGRPYHG 293 Query: 370 KIADVWSRGVTLYVML 417 +DVWS G+ L+ +L Sbjct: 294 GPSDVWSCGIVLFALL 309
>SN1L2_MOUSE (Q8CFH6) Serine/threonine-protein kinase SNF1-like kinase 2 (EC| 2.7.11.1) (Salt-inducible kinase 2) Length = 931 Score = 119 bits (297), Expect = 4e-27 Identities = 61/137 (44%), Positives = 84/137 (61%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P+II+ +V+ T + L +V EYA GE+F+ + N GR +E EAR F Q+LS V YCH Sbjct: 77 PHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGR 136 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 +V HRDLK EN LLD + +KI DFG+ + G+P Y APEV ++Y+ Sbjct: 137 KVVHRDLKAENLLLDNNM--NIKIADFGFGNFFKTGELLATWCGSPPYAAPEVFEGQQYE 194 Query: 367 GKIADVWSRGVTLYVML 417 G D+WS GV LYV++ Sbjct: 195 GPQLDIWSMGVVLYVLV 211
>SN1L2_CHICK (Q9IA88) Serine/threonine-protein kinase SNF1-like kinase 2 (EC| 2.7.11.1) (Qin-induced kinase) Length = 798 Score = 118 bits (295), Expect = 6e-27 Identities = 64/138 (46%), Positives = 86/138 (62%), Gaps = 1/138 (0%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P+II+ +V+ T L IV E+A GE+F+ + + G SE EAR F Q+LS V YCHS Sbjct: 83 PHIIKLYQVMETKDMLYIVTEFAKNGEMFDHLTSNGHLSESEARKKFWQILSAVEYCHSH 142 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKST-VGTPAYIAPEVLLKKEY 363 + HRDLK EN LLD + +K+ DFG+ + +P ST G+P Y APEV KEY Sbjct: 143 HIVHRDLKTENLLLDANM--NIKLADFGFG-NFYKSGEPLSTWCGSPPYAAPEVFEGKEY 199 Query: 364 DGKIADVWSRGVTLYVML 417 +G D+WS GV LYV++ Sbjct: 200 EGPHLDIWSLGVVLYVLV 217
>AAPK1_CAEEL (P45894) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMP-activated kinase 1) Length = 589 Score = 118 bits (295), Expect = 6e-27 Identities = 64/137 (46%), Positives = 81/137 (59%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P+I R VI TP+ + +VME SGGELF I G E+R +FQQ++SGVSYCH+ Sbjct: 82 PHITRLFRVISTPSDIFLVMELVSGGELFSYITRKGALPIRESRRYFQQIISGVSYCHNH 141 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 + HRDLK EN LLD + +KI DFG S + G+P Y APE++ K Y Sbjct: 142 MIVHRDLKPENLLLDAN--KNIKIADFGLSNYMTDGDLLSTACGSPNYAAPELISNKLYV 199 Query: 367 GKIADVWSRGVTLYVML 417 G D+WS GV LY ML Sbjct: 200 GPEVDLWSCGVILYAML 216
>SN1L2_HUMAN (Q9H0K1) Serine/threonine-protein kinase SNF1-like kinase 2 (EC| 2.7.11.1) (Qin-induced kinase) Length = 926 Score = 118 bits (295), Expect = 6e-27 Identities = 60/137 (43%), Positives = 84/137 (61%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P+II+ +V+ T + L +V EYA GE+F+ + N GR +E EAR F Q+LS V YCH Sbjct: 77 PHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGR 136 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 ++ HRDLK EN LLD + +KI DFG+ + G+P Y APEV ++Y+ Sbjct: 137 KIVHRDLKAENLLLDNNM--NIKIADFGFGNFFKSGELLATWCGSPPYAAPEVFEGQQYE 194 Query: 367 GKIADVWSRGVTLYVML 417 G D+WS GV LYV++ Sbjct: 195 GPQLDIWSMGVVLYVLV 211
>SNF1_CANTR (O94168) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 619 Score = 117 bits (294), Expect = 8e-27 Identities = 65/137 (47%), Positives = 86/137 (62%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P+II+ +VI + + +V+E+A G ELF+ I G+ EDEAR FFQQ+++ V YCH Sbjct: 110 PHIIKLYDVIKSKDEIIMVIEFA-GKELFDYIVQRGKMPEDEARRFFQQIIAAVEYCHRH 168 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 ++ HRDLK EN LLD +KI DFG S + K++ G+P Y APEV+ K Y Sbjct: 169 KIVHRDLKPENLLLDDQL--NVKIADFGLSNIMTDGNFLKTSCGSPNYAAPEVISGKLYA 226 Query: 367 GKIADVWSRGVTLYVML 417 G DVWS GV LYVML Sbjct: 227 GPEVDVWSSGVILYVML 243
>SN1L1_HUMAN (P57059) Serine/threonine-protein kinase SNF1-like kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase SNF1LK) Length = 783 Score = 117 bits (294), Expect = 8e-27 Identities = 64/138 (46%), Positives = 87/138 (63%), Gaps = 1/138 (0%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P+II+ +V+ T L IV E+A GE+F+ + + G SE+EAR F Q+LS V YCH Sbjct: 84 PHIIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQILSAVEYCHDH 143 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKST-VGTPAYIAPEVLLKKEY 363 + HRDLK EN LLDG+ +K+ DFG+ + +P ST G+P Y APEV KEY Sbjct: 144 HIVHRDLKTENLLLDGNM--DIKLADFGFG-NFYKSGEPLSTWCGSPPYAAPEVFEGKEY 200 Query: 364 DGKIADVWSRGVTLYVML 417 +G D+WS GV LYV++ Sbjct: 201 EGPQLDIWSLGVVLYVLV 218
>RKIN1_SECCE (Q02723) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 502 Score = 117 bits (292), Expect = 1e-26 Identities = 67/139 (48%), Positives = 85/139 (61%), Gaps = 2/139 (1%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P+IIR EVI+TP + +VMEY G+L + I R EDEAR FQQ++S V YCH Sbjct: 75 PHIIRVYEVIVTPKDIFVVMEYCQNGDLLDYILEKRRLQEDEARRTFQQIISAVEYCHRN 134 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQP--KSTVGTPAYIAPEVLLKKE 360 +V HRDLK EN LLD +K+ DFG S+V+H K++ G+ Y APEV+ K Sbjct: 135 KVVHRDLKPENLLLDSKY--NVKLADFGL--SNVMHDGHFLKTSCGSLNYAAPEVISGKL 190 Query: 361 YDGKIADVWSRGVTLYVML 417 Y G DVWS GV LY +L Sbjct: 191 YAGPEIDVWSCGVILYALL 209
>SNF1_CANGA (Q00372) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 612 Score = 117 bits (292), Expect = 1e-26 Identities = 66/137 (48%), Positives = 85/137 (62%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P+II+ +VI + + +V+EYA G ELF+ I + SE EAR FFQQ++S V YCH Sbjct: 97 PHIIKLYDVIKSKDEIIMVIEYA-GNELFDYIVQRNKMSEQEARRFFQQIISAVEYCHRH 155 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 ++ HRDLK EN LLD +KI DFG S + K++ G+P Y APEV+ K Y Sbjct: 156 KIVHRDLKPENLLLDEHL--NVKIADFGLSNIMTDGNFLKTSCGSPNYAAPEVISGKLYA 213 Query: 367 GKIADVWSRGVTLYVML 417 G DVWS GV LYVML Sbjct: 214 GPEVDVWSCGVILYVML 230
>SNF1_YEAST (P06782) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 633 Score = 116 bits (291), Expect = 2e-26 Identities = 66/137 (48%), Positives = 85/137 (62%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P+II+ +VI + + +V+EYA G ELF+ I + SE EAR FFQQ++S V YCH Sbjct: 113 PHIIKLYDVIKSKDEIIMVIEYA-GNELFDYIVQRDKMSEQEARRFFQQIISAVEYCHRH 171 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 ++ HRDLK EN LLD +KI DFG S + K++ G+P Y APEV+ K Y Sbjct: 172 KIVHRDLKPENLLLDEHL--NVKIADFGLSNIMTDGNFLKTSCGSPNYAAPEVISGKLYA 229 Query: 367 GKIADVWSRGVTLYVML 417 G DVWS GV LYVML Sbjct: 230 GPEVDVWSCGVILYVML 246
>SN1L2_PONPY (Q5REX1) Serine/threonine-protein kinase SNF1-like kinase 2 (EC| 2.7.11.1) Length = 925 Score = 115 bits (287), Expect = 5e-26 Identities = 59/137 (43%), Positives = 83/137 (60%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P+II+ +V+ T + L +V EYA GE+F+ + N GR +E EAR F Q+LS V YCH Sbjct: 77 PHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGR 136 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 ++ HRDLK EN LLD + +KI DF + + G+P Y APEV ++Y+ Sbjct: 137 KIVHRDLKAENLLLDNNM--NIKIADFSFGNFFKSGELLATWRGSPPYAAPEVFEGQQYE 194 Query: 367 GKIADVWSRGVTLYVML 417 G D+WS GV LYV++ Sbjct: 195 GPQLDIWSMGVVLYVLV 211
>MARK3_HUMAN (P27448) MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1)| (Cdc25C-associated protein kinase 1) (cTAK1) (C-TAK1) (Serine/threonine protein kinase p78) (Ser/Thr protein kinase PAR-1) (Protein kinase STK10) Length = 776 Score = 114 bits (286), Expect = 7e-26 Identities = 64/160 (40%), Positives = 86/160 (53%), Gaps = 23/160 (14%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQ----------- 153 PNI++ EVI T L ++MEYASGGE+F+ + GR E EAR F+Q Sbjct: 113 PNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQGCQAGQTIKVQ 172 Query: 154 ------------LLSGVSYCHSMQVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHS 297 ++S V YCH ++ HRDLK EN LLD +KI DFG+S + Sbjct: 173 VSFDLLSLMFTFIVSAVQYCHQKRIVHRDLKAENLLLDADM--NIKIADFGFSNEFTVGG 230 Query: 298 QPKSTVGTPAYIAPEVLLKKEYDGKIADVWSRGVTLYVML 417 + + G+P Y APE+ K+YDG DVWS GV LY ++ Sbjct: 231 KLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLV 270
>SNF1_CANAL (P52497) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 620 Score = 114 bits (284), Expect = 1e-25 Identities = 65/138 (47%), Positives = 87/138 (63%), Gaps = 1/138 (0%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P+II+ +VI + + +V+E+A G ELF+ I G+ EDEAR FFQQ+++ V YCH Sbjct: 111 PHIIKLYDVIKSKDEIIMVIEFA-GKELFDYIVQRGKMPEDEARRFFQQIIAAVEYCHRH 169 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYI-APEVLLKKEY 363 ++ HRDLK EN LLD +KI DFG S + K++ G+P Y+ APEV+ K Y Sbjct: 170 KIVHRDLKPENLLLDDQL--NVKIADFGLSNIMTDGNFLKTSCGSPNYMPAPEVISGKLY 227 Query: 364 DGKIADVWSRGVTLYVML 417 G DVWS GV LYVML Sbjct: 228 AGPEVDVWSAGVILYVML 245
>KCC4_MOUSE (P08414) Calcium/calmodulin-dependent protein kinase type IV (EC| 2.7.11.17) (CAM kinase-GR) (CaMK IV) Length = 469 Score = 113 bits (282), Expect = 2e-25 Identities = 64/139 (46%), Positives = 85/139 (61%), Gaps = 2/139 (1%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PNII+ KE+ TPT +++V+E +GGELF+RI G +SE +AR +Q+L V+Y H Sbjct: 95 PNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDARDAVKQILEAVAYLHEN 154 Query: 187 QVCHRDLKLENTLLDGSTAP--RLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKE 360 + HRDLK EN LL + AP LKI DFG SK K+ GTP Y APE+L Sbjct: 155 GIVHRDLKPEN-LLYATPAPDAPLKIADFGLSKIVEHQVLMKTVCGTPGYCAPEILRGCA 213 Query: 361 YDGKIADVWSRGVTLYVML 417 Y G D+WS G+ Y++L Sbjct: 214 Y-GPEVDMWSVGIITYILL 231
>KCC4_HUMAN (Q16566) Calcium/calmodulin-dependent protein kinase type IV (EC| 2.7.11.17) (CAM kinase-GR) (CaMK IV) Length = 473 Score = 110 bits (276), Expect = 1e-24 Identities = 63/139 (45%), Positives = 84/139 (60%), Gaps = 2/139 (1%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PNII+ KE+ TPT +++V+E +GGELF+RI G +SE +A +Q+L V+Y H Sbjct: 99 PNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAVAYLHEN 158 Query: 187 QVCHRDLKLENTLLDGSTAP--RLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKE 360 + HRDLK EN LL + AP LKI DFG SK K+ GTP Y APE+L Sbjct: 159 GIVHRDLKPEN-LLYATPAPDAPLKIADFGLSKIVEHQVLMKTVCGTPGYCAPEILRGCA 217 Query: 361 YDGKIADVWSRGVTLYVML 417 Y G D+WS G+ Y++L Sbjct: 218 Y-GPEVDMWSVGIITYILL 235
>GIN4_YEAST (Q12263) Serine/threonine-protein kinase GIN4 (EC 2.7.11.1)| Length = 1142 Score = 110 bits (276), Expect = 1e-24 Identities = 59/137 (43%), Positives = 82/137 (59%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PN++R +V T T L +V+EYA GELF + G E EA FF+Q++ GVSYCH++ Sbjct: 91 PNVLRLYDVWETNTDLYLVLEYAEKGELFNLLVERGPLPEHEAIRFFRQIIIGVSYCHAL 150 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 + HRDLK EN LLD +KI DFG + +++ G+P Y APE++ Y Sbjct: 151 GIVHRDLKPENLLLDHKY--NIKIADFGMAALETEGKLLETSCGSPHYAAPEIVSGIPYQ 208 Query: 367 GKIADVWSRGVTLYVML 417 G +DVWS GV L+ +L Sbjct: 209 GFASDVWSCGVILFALL 225
>KCC4_RAT (P13234) Calcium/calmodulin-dependent protein kinase type IV (EC| 2.7.11.17) (CAM kinase-GR) (CaMK IV) (Calspermin) Length = 474 Score = 110 bits (276), Expect = 1e-24 Identities = 63/139 (45%), Positives = 84/139 (60%), Gaps = 2/139 (1%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PNII+ KE+ TPT +++V+E +GGELF+RI G +SE +A +Q+L V+Y H Sbjct: 95 PNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAVAYLHEN 154 Query: 187 QVCHRDLKLENTLLDGSTAP--RLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKE 360 + HRDLK EN LL + AP LKI DFG SK K+ GTP Y APE+L Sbjct: 155 GIVHRDLKPEN-LLYATPAPDAPLKIADFGLSKIVEHQVLMKTVCGTPGYCAPEILRGCA 213 Query: 361 YDGKIADVWSRGVTLYVML 417 Y G D+WS G+ Y++L Sbjct: 214 Y-GPEVDMWSVGIITYILL 231
>NUAK1_MOUSE (Q641K5) NUAK family, SNF1-like kinase 1 (EC 2.7.11.1)| Length = 658 Score = 109 bits (273), Expect = 2e-24 Identities = 59/137 (43%), Positives = 79/137 (57%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P+II EV + I+MEYAS GEL++ I R SE E R FF+Q++S V YCH Sbjct: 114 PHIISIYEVFENKDKIVIIMEYASKGELYDYISERRRLSERETRHFFRQIVSAVHYCHKN 173 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 V HRDLKLEN LLD + +KI DFG S ++ G+P Y +PE++ + Y Sbjct: 174 GVVHRDLKLENILLDDNC--NIKIADFGLSNLYQKDKFLQTFCGSPLYASPEIVNGRPYR 231 Query: 367 GKIADVWSRGVTLYVML 417 G D W+ GV LY ++ Sbjct: 232 GPEVDSWALGVLLYTLI 248
>NUAK1_HUMAN (O60285) NUAK family, SNF1-like kinase 1 (EC 2.7.11.1)| (AMPK-related protein kinase 5) Length = 661 Score = 109 bits (272), Expect = 3e-24 Identities = 59/137 (43%), Positives = 79/137 (57%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P+II EV + I+MEYAS GEL++ I R SE E R FF+Q++S V YCH Sbjct: 113 PHIISIYEVFENKDKIVIIMEYASKGELYDYISERRRLSERETRHFFRQIVSAVHYCHKN 172 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 V HRDLKLEN LLD + +KI DFG S ++ G+P Y +PE++ + Y Sbjct: 173 GVVHRDLKLENILLDDNC--NIKIADFGLSNLYQKDKFLQTFCGSPLYASPEIVNGRPYR 230 Query: 367 GKIADVWSRGVTLYVML 417 G D W+ GV LY ++ Sbjct: 231 GPEVDSWALGVLLYTLV 247
>CDR2_SCHPO (P87050) Mitosis inducer protein kinase cdr2 (EC 2.7.11.1)| Length = 775 Score = 109 bits (272), Expect = 3e-24 Identities = 50/137 (36%), Positives = 82/137 (59%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PN+++ +VI L +V+EY GGELF+ + G F+E + F Q+L G+ YCH + Sbjct: 68 PNVLQLIDVISAQEQLFVVVEYMPGGELFDCMLRKGSFTEQDTAKFLWQILCGLEYCHKL 127 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 +CHRDLK EN LD + +KI +FG + +++ G+P Y +PE+++ + YD Sbjct: 128 HICHRDLKPENLYLDAHGS--IKIGEFGMASIQQPGKLLQTSCGSPHYASPEIIMGRSYD 185 Query: 367 GKIADVWSRGVTLYVML 417 G +D+WS G+ + +L Sbjct: 186 GCASDIWSCGIIFFALL 202
>YP141_YEAST (Q03002) Putative serine/threonine-protein kinase YPL141C (EC| 2.7.11.1) Length = 865 Score = 108 bits (271), Expect = 4e-24 Identities = 60/139 (43%), Positives = 85/139 (61%), Gaps = 2/139 (1%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PNI++ +EV+ ++ IV+EYA GGE ++ I R E A F QL+SGV Y HS Sbjct: 110 PNIVKLEEVLQNSRYIGIVLEYACGGEFYKYIQKKRRLKEMNACRLFSQLISGVHYIHSK 169 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQ-PKSTVGTPAYIAPEVLLKKE- 360 + HRDLKLEN LLD + L I DFG+ ++ K++ G+P Y APE+++ E Sbjct: 170 GLVHRDLKLENLLLDKN--ENLVITDFGFVNEFCSRNELMKTSCGSPCYAAPELVISAEP 227 Query: 361 YDGKIADVWSRGVTLYVML 417 Y+ + AD+WS GV LY +L Sbjct: 228 YEARKADIWSCGVILYAIL 246
>KCC1B_RAT (O70150) Calcium/calmodulin-dependent protein kinase type 1B (EC| 2.7.11.17) (CaM kinase IB) (CaM kinase I beta) (CaMKI-beta) (CaM-KI beta) (Pregnancy up-regulated non-ubiquitously expressed CaM kinase homolog) Length = 343 Score = 107 bits (266), Expect = 1e-23 Identities = 58/138 (42%), Positives = 83/138 (60%), Gaps = 1/138 (0%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PNI+ ++V +P+HL + ME +GGELF+RI G ++E +A Q+L VSY HS+ Sbjct: 71 PNIVALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAVSYLHSL 130 Query: 187 QVCHRDLKLENTL-LDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEY 363 + HRDLK EN L ++ + DFG SK + + GTP Y+APE+L +K Y Sbjct: 131 GIVHRDLKPENLLYATPFEDSKIMVSDFGLSKIQA-GNMLGTACGTPGYVAPELLEQKPY 189 Query: 364 DGKIADVWSRGVTLYVML 417 GK DVW+ GV Y++L Sbjct: 190 -GKAVDVWALGVISYILL 206
>KCC1B_MOUSE (Q9QYK9) Calcium/calmodulin-dependent protein kinase type 1B (EC| 2.7.11.17) (CaM kinase IB) (CaM kinase I beta) (CaMKI-beta) (CaM-KI beta) (Pregnancy up-regulated non-ubiquitously expressed CaM kinase homolog) Length = 343 Score = 107 bits (266), Expect = 1e-23 Identities = 58/138 (42%), Positives = 83/138 (60%), Gaps = 1/138 (0%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PNI+ ++V +P+HL + ME +GGELF+RI G ++E +A Q+L VSY HS+ Sbjct: 71 PNIVALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAVSYLHSL 130 Query: 187 QVCHRDLKLENTL-LDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEY 363 + HRDLK EN L ++ + DFG SK + + GTP Y+APE+L +K Y Sbjct: 131 GIVHRDLKPENLLYATPFEDSKIMVSDFGLSKIQA-GNMLGTACGTPGYVAPELLEQKPY 189 Query: 364 DGKIADVWSRGVTLYVML 417 GK DVW+ GV Y++L Sbjct: 190 -GKAVDVWALGVISYILL 206
>KCC1B_HUMAN (Q6P2M8) Calcium/calmodulin-dependent protein kinase type 1B (EC| 2.7.11.17) (CaM kinase IB) (CaM kinase I beta) (CaMKI-beta) (CaM-KI beta) (Pregnancy up-regulated non-ubiquitously expressed CaM kinase) Length = 343 Score = 107 bits (266), Expect = 1e-23 Identities = 58/138 (42%), Positives = 83/138 (60%), Gaps = 1/138 (0%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PNI+ ++V +P+HL + ME +GGELF+RI G ++E +A Q+L VSY HS+ Sbjct: 71 PNIVALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAVSYLHSL 130 Query: 187 QVCHRDLKLENTL-LDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEY 363 + HRDLK EN L ++ + DFG SK + + GTP Y+APE+L +K Y Sbjct: 131 GIVHRDLKPENLLYATPFEDSKIMVSDFGLSKIQA-GNMLGTACGTPGYVAPELLEQKPY 189 Query: 364 DGKIADVWSRGVTLYVML 417 GK DVW+ GV Y++L Sbjct: 190 -GKAVDVWALGVISYILL 206
>MYLK_DICDI (P25323) Myosin light chain kinase (EC 2.7.11.18) (MLCK)| Length = 295 Score = 107 bits (266), Expect = 1e-23 Identities = 60/138 (43%), Positives = 81/138 (58%), Gaps = 1/138 (0%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PNII KE+ TP L +VME +GGELF++I G +SE +A ++++S V Y H + Sbjct: 65 PNIIALKELFDTPEKLYLVMELVTGGELFDKIVEKGSYSEADAANLVKKIVSAVGYLHGL 124 Query: 187 QVCHRDLKLENTLLDG-STAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEY 363 + HRDLK EN LL + I DFG SK ++ GTP+Y+APEVL Y Sbjct: 125 NIVHRDLKPENLLLKSKENHLEVAIADFGLSKIIGQTLVMQTACGTPSYVAPEVLNATGY 184 Query: 364 DGKIADVWSRGVTLYVML 417 D K D+WS GV Y++L Sbjct: 185 D-KEVDMWSIGVITYILL 201
>KCC1D_MOUSE (Q8BW96) Calcium/calmodulin-dependent protein kinase type 1D (EC| 2.7.11.17) (CaM kinase ID) (CaM kinase I delta) (CaMKI-delta) (CaM-KI delta) (CaMKI delta) (Camk1D) (CamKI-like protein kinase) (CKLiK) (mCKLiK) Length = 385 Score = 107 bits (266), Expect = 1e-23 Identities = 57/137 (41%), Positives = 78/137 (56%), Gaps = 1/137 (0%) Frame = +1 Query: 10 NIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSMQ 189 NI+ +++ +P HL +VM+ SGGELF+RI G ++E +A +Q+L V Y H M Sbjct: 80 NIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMG 139 Query: 190 VCHRDLKLENTL-LDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 + HRDLK EN L ++ I DFG SK + GTP Y+APEVL +K Y Sbjct: 140 IVHRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAPEVLAQKPY- 198 Query: 367 GKIADVWSRGVTLYVML 417 K D WS GV Y++L Sbjct: 199 SKAVDCWSIGVIAYILL 215
>KCC1D_HUMAN (Q8IU85) Calcium/calmodulin-dependent protein kinase type 1D (EC| 2.7.11.17) (CaM kinase ID) (CaM kinase I delta) (CaMKI-delta) (CaM-KI delta) (CaMKI delta) (Camk1D) (CamKI-like protein kinase) (CKLiK) Length = 385 Score = 107 bits (266), Expect = 1e-23 Identities = 57/137 (41%), Positives = 78/137 (56%), Gaps = 1/137 (0%) Frame = +1 Query: 10 NIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSMQ 189 NI+ +++ +P HL +VM+ SGGELF+RI G ++E +A +Q+L V Y H M Sbjct: 80 NIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMG 139 Query: 190 VCHRDLKLENTL-LDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 + HRDLK EN L ++ I DFG SK + GTP Y+APEVL +K Y Sbjct: 140 IVHRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAPEVLAQKPY- 198 Query: 367 GKIADVWSRGVTLYVML 417 K D WS GV Y++L Sbjct: 199 SKAVDCWSIGVIAYILL 215
>HUNK_PANTR (Q68UT7) Hormonally up-regulated neu tumor-associated kinase (EC| 2.7.11.1) Length = 714 Score = 106 bits (265), Expect = 2e-23 Identities = 62/140 (44%), Positives = 83/140 (59%), Gaps = 3/140 (2%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PNI + +++ T +VME GG L +I R E EAR + +QL+S V + H Sbjct: 121 PNITQLLDILETENSYYLVMELCPGGNLMHKIYEKKRLEESEARRYIRQLISAVEHLHRA 180 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVL--HSQPKST-VGTPAYIAPEVLLKK 357 V HRDLK+EN LLD +K+ DFG S + + +S P ST G+PAY APE+L +K Sbjct: 181 GVVHRDLKIENLLLDEDN--NIKLIDFGLSNCAGILGYSDPFSTQCGSPAYAAPELLARK 238 Query: 358 EYDGKIADVWSRGVTLYVML 417 +Y KI DVWS GV +Y ML Sbjct: 239 KYGPKI-DVWSIGVNMYAML 257
>HUNK_HUMAN (P57058) Hormonally up-regulated neu tumor-associated kinase (EC| 2.7.11.1) (Serine/threonine-protein kinase MAK-V) (B19) Length = 714 Score = 106 bits (265), Expect = 2e-23 Identities = 62/140 (44%), Positives = 83/140 (59%), Gaps = 3/140 (2%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PNI + +++ T +VME GG L +I R E EAR + +QL+S V + H Sbjct: 121 PNITQLLDILETENSYYLVMELCPGGNLMHKIYEKKRLEESEARRYIRQLISAVEHLHRA 180 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVL--HSQPKST-VGTPAYIAPEVLLKK 357 V HRDLK+EN LLD +K+ DFG S + + +S P ST G+PAY APE+L +K Sbjct: 181 GVVHRDLKIENLLLDEDN--NIKLIDFGLSNCAGILGYSDPFSTQCGSPAYAAPELLARK 238 Query: 358 EYDGKIADVWSRGVTLYVML 417 +Y KI DVWS GV +Y ML Sbjct: 239 KYGPKI-DVWSIGVNMYAML 257
>KIN4_YEAST (Q01919) Serine/threonine-protein kinase KIN4 (EC 2.7.11.1)| Length = 800 Score = 105 bits (263), Expect = 3e-23 Identities = 61/139 (43%), Positives = 83/139 (59%), Gaps = 2/139 (1%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PNII +EV+ ++ IV+E+ SGGE ++ I R E A F QL+SGV+Y H Sbjct: 110 PNIIYLEEVLQNSKYIGIVLEFVSGGEFYKYIQRKRRLKESSACRLFAQLISGVNYMHYK 169 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQ-PKSTVGTPAYIAPEVLLK-KE 360 + HRDLKLEN LLD L I DFG+ ++ K++ G+P Y APE+++ K Sbjct: 170 GLVHRDLKLENLLLD--KHENLVITDFGFVNEFFEDNELMKTSCGSPCYAAPELVVSTKA 227 Query: 361 YDGKIADVWSRGVTLYVML 417 Y+ + ADVWS GV LY ML Sbjct: 228 YEARKADVWSCGVILYAML 246
>HUNK_MOUSE (O88866) Hormonally up-regulated neu tumor-associated kinase (EC| 2.7.11.1) (Serine/threonine-protein kinase MAK-V) Length = 714 Score = 105 bits (263), Expect = 3e-23 Identities = 62/140 (44%), Positives = 83/140 (59%), Gaps = 3/140 (2%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PNI + +++ T +VME GG L +I R E EAR + +QL+S V + H Sbjct: 121 PNITQLLDILETENSYYLVMELCPGGNLMHKIYEKKRLDEAEARRYIRQLISAVEHLHRA 180 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVL--HSQPKST-VGTPAYIAPEVLLKK 357 V HRDLK+EN LLD +K+ DFG S + + +S P ST G+PAY APE+L +K Sbjct: 181 GVVHRDLKIENLLLDEDN--NIKLIDFGLSNCAGILGYSDPFSTQCGSPAYAAPELLARK 238 Query: 358 EYDGKIADVWSRGVTLYVML 417 +Y KI DVWS GV +Y ML Sbjct: 239 KYGPKI-DVWSIGVNMYAML 257
>KS6A5_PONPY (Q5R4K3) Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1)| Length = 802 Score = 105 bits (261), Expect = 6e-23 Identities = 62/139 (44%), Positives = 83/139 (59%), Gaps = 2/139 (1%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PNI++ EV H +VME +GGELFERI FSE EA + ++L+S VS+ H + Sbjct: 479 PNIVKLHEVFHDQLHTFLVMELLNGGELFERIKKKKHFSETEASYIMRKLVSAVSHMHDV 538 Query: 187 QVCHRDLKLENTLL-DGSTAPRLKICDFGYSKSSVLHSQP-KSTVGTPAYIAPEVLLKKE 360 V HRDLK EN L D + +KI DFG+++ +QP K+ T Y APE+L + Sbjct: 539 GVVHRDLKPENLLFTDENDNLEIKIIDFGFARPKPPDNQPLKTPCFTLHYAAPELLNQNG 598 Query: 361 YDGKIADVWSRGVTLYVML 417 YD + D+WS GV LY ML Sbjct: 599 YD-ESCDLWSLGVILYTML 616 Score = 79.0 bits (193), Expect = 4e-15 Identities = 44/140 (31%), Positives = 75/140 (53%), Gaps = 3/140 (2%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P ++ T T L ++++Y +GGELF + RF+E E + + +++ + + H + Sbjct: 112 PFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLALEHLHKL 171 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPK--STVGTPAYIAPEVLLKKE 360 + +RD+KLEN LLD + + + DFG SK V + S GT Y+AP+++ + Sbjct: 172 GIIYRDIKLENILLDSN--GHVMLTDFGLSKEFVADETERAYSFCGTIEYMAPDIVRGGD 229 Query: 361 Y-DGKIADVWSRGVTLYVML 417 K D WS GV +Y +L Sbjct: 230 SGHDKAVDWWSLGVLMYELL 249
>KPSH1_BRARE (Q501V0) Serine/threonine-protein kinase H1 homolog (EC 2.7.11.1)| Length = 422 Score = 104 bits (260), Expect = 7e-23 Identities = 59/139 (42%), Positives = 84/139 (60%), Gaps = 3/139 (2%) Frame = +1 Query: 10 NIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSMQ 189 NII+ EV T + +VME A+GGELF+RI G F+E +A Q +L GV Y H++ Sbjct: 152 NIIQLMEVFETAERVYMVMELATGGELFDRIITRGSFTERDATRVLQMVLDGVKYLHTLG 211 Query: 190 VCHRDLKLENTLLDGSTA-PRLKICDFGYSKSSVLHSQ--PKSTVGTPAYIAPEVLLKKE 360 + HRDLK EN L A ++ I DFG + + + K+T GTP YIAPE+L++K Sbjct: 212 ITHRDLKPENLLYYHPGADSKIMITDFGLASTRKKGDECLMKTTCGTPEYIAPEILVRKP 271 Query: 361 YDGKIADVWSRGVTLYVML 417 Y + D+W+ GV Y++L Sbjct: 272 YTNAV-DMWALGVISYILL 289
>CDPK1_PLAFK (P62343) Calcium-dependent protein kinase 1 (EC 2.7.11.1) (PfCPK)| (PfCDPK1) Length = 523 Score = 104 bits (260), Expect = 7e-23 Identities = 59/138 (42%), Positives = 84/138 (60%), Gaps = 1/138 (0%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PNII+ +V + +V E+ GGELFE+I N +F E +A +Q+LSG+ Y H Sbjct: 125 PNIIKLFDVFEDKKYFYLVTEFYEGGELFEQIINRHKFDECDAANIMKQILSGICYLHKH 184 Query: 187 QVCHRDLKLENTLLDGS-TAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEY 363 + HRD+K EN LL+ + +KI DFG S ++ + +GT YIAPEV L+K+Y Sbjct: 185 NIVHRDIKPENILLENKHSLLNIKIVDFGLSSFFSKDNKLRDRLGTAYYIAPEV-LRKKY 243 Query: 364 DGKIADVWSRGVTLYVML 417 + K DVWS GV LY++L Sbjct: 244 NEK-CDVWSCGVILYILL 260
>CDPK1_PLAF7 (P62344) Calcium-dependent protein kinase 1 (EC 2.7.11.1)| Length = 523 Score = 104 bits (260), Expect = 7e-23 Identities = 59/138 (42%), Positives = 84/138 (60%), Gaps = 1/138 (0%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PNII+ +V + +V E+ GGELFE+I N +F E +A +Q+LSG+ Y H Sbjct: 125 PNIIKLFDVFEDKKYFYLVTEFYEGGELFEQIINRHKFDECDAANIMKQILSGICYLHKH 184 Query: 187 QVCHRDLKLENTLLDGS-TAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEY 363 + HRD+K EN LL+ + +KI DFG S ++ + +GT YIAPEV L+K+Y Sbjct: 185 NIVHRDIKPENILLENKHSLLNIKIVDFGLSSFFSKDNKLRDRLGTAYYIAPEV-LRKKY 243 Query: 364 DGKIADVWSRGVTLYVML 417 + K DVWS GV LY++L Sbjct: 244 NEK-CDVWSCGVILYILL 260
>KCC1G_MOUSE (Q91VB2) Calcium/calmodulin-dependent protein kinase type 1G (EC| 2.7.11.17) (CaM kinase IG) (CaM kinase I gamma) (CaMKI gamma) (CaMKI-gamma) (CaM-KI gamma) (CaMKIG) (CaMK-like CREB kinase III) (CLICK III) Length = 477 Score = 104 bits (260), Expect = 7e-23 Identities = 58/137 (42%), Positives = 79/137 (57%), Gaps = 1/137 (0%) Frame = +1 Query: 10 NIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSMQ 189 NI+ +++ + TH +VM+ SGGELF+RI G ++E +A QQ+LS V Y H Sbjct: 79 NIVTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKYLHENG 138 Query: 190 VCHRDLKLENTL-LDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 + HRDLK EN L L ++ I DFG SK + + GTP Y+APEVL +K Y Sbjct: 139 IVHRDLKPENLLYLTPEENSKIMITDFGLSKME-QNGVMSTACGTPGYVAPEVLAQKPY- 196 Query: 367 GKIADVWSRGVTLYVML 417 K D WS GV Y++L Sbjct: 197 SKAVDCWSIGVITYILL 213
>CHK1_SCHPO (P34208) Serine/threonine-protein kinase chk1 (EC 2.7.11.1)| (Checkpoint kinase 1) Length = 496 Score = 104 bits (260), Expect = 7e-23 Identities = 62/143 (43%), Positives = 85/143 (59%), Gaps = 7/143 (4%) Frame = +1 Query: 10 NIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSMQ 189 NII F P +V+E+A GG+LF++I ED A+F+F QL+ G+S+ HS Sbjct: 73 NIIHFYNTAENPQWRWVVLEFAQGGDLFDKIEPDVGIDEDVAQFYFAQLMEGISFMHSKG 132 Query: 190 VCHRDLKLENTLLDGSTAPRLKICDFGYS-------KSSVLHSQPKSTVGTPAYIAPEVL 348 V HRDLK EN LLD + LKI DFG++ KS +L+ S VG+P Y APE+ Sbjct: 133 VAHRDLKPENILLDYN--GNLKISDFGFASLFSYKGKSRLLN----SPVGSPPYAAPEI- 185 Query: 349 LKKEYDGKIADVWSRGVTLYVML 417 ++YDG DVWS G+ L+ +L Sbjct: 186 -TQQYDGSKVDVWSCGIILFALL 207
>KS6A5_HUMAN (O75582) Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1) (Nuclear| mitogen-and stress-activated protein kinase 1) (90 kDa ribosomal protein S6 kinase 5) (RSK-like protein kinase) (RSKL) Length = 802 Score = 104 bits (260), Expect = 7e-23 Identities = 62/139 (44%), Positives = 83/139 (59%), Gaps = 2/139 (1%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PNI++ EV H +VME +GGELFERI FSE EA + ++L+S VS+ H + Sbjct: 479 PNIVKLHEVFHDQLHTFLVMELLNGGELFERIKKKKHFSETEASYIMRKLVSAVSHMHDV 538 Query: 187 QVCHRDLKLENTLL-DGSTAPRLKICDFGYSKSSVLHSQP-KSTVGTPAYIAPEVLLKKE 360 V HRDLK EN L D + +KI DFG+++ +QP K+ T Y APE+L + Sbjct: 539 GVVHRDLKPENLLFTDENDNLEIKIIDFGFARLKPPDNQPLKTPCFTLHYAAPELLNQNG 598 Query: 361 YDGKIADVWSRGVTLYVML 417 YD + D+WS GV LY ML Sbjct: 599 YD-ESCDLWSLGVILYTML 616 Score = 78.6 bits (192), Expect = 6e-15 Identities = 44/140 (31%), Positives = 75/140 (53%), Gaps = 3/140 (2%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P ++ T T L ++++Y +GGELF + RF+E E + + +++ + + H + Sbjct: 112 PFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLALEHLHKL 171 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPK--STVGTPAYIAPEVLLKKE 360 + +RD+KLEN LLD + + + DFG SK V + S GT Y+AP+++ + Sbjct: 172 GIIYRDIKLENILLDSN--GHVVLTDFGLSKEFVADETERAYSFCGTIEYMAPDIVRGGD 229 Query: 361 Y-DGKIADVWSRGVTLYVML 417 K D WS GV +Y +L Sbjct: 230 SGHDKAVDWWSLGVLMYELL 249
>KCC1G_RAT (Q7TNJ7) Calcium/calmodulin-dependent protein kinase type 1G (EC| 2.7.11.17) (CaM kinase IG) (CaM kinase I gamma) (CaMKI gamma) (CaMKI-gamma) (CaM-KI gamma) (CaMKIG) (CaMK-like CREB kinase III) (CLICK III) Length = 476 Score = 104 bits (260), Expect = 7e-23 Identities = 58/137 (42%), Positives = 79/137 (57%), Gaps = 1/137 (0%) Frame = +1 Query: 10 NIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSMQ 189 NI+ +++ + TH +VM+ SGGELF+RI G ++E +A QQ+LS V Y H Sbjct: 79 NIVTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKYLHENG 138 Query: 190 VCHRDLKLENTL-LDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 + HRDLK EN L L ++ I DFG SK + + GTP Y+APEVL +K Y Sbjct: 139 IVHRDLKPENLLYLTPEENSKIMITDFGLSKME-QNGVMSTACGTPGYVAPEVLAQKPY- 196 Query: 367 GKIADVWSRGVTLYVML 417 K D WS GV Y++L Sbjct: 197 SKAVDCWSIGVITYILL 213
>KK31_SCHPO (Q9HFF4) Probable serine/threonine-protein kinase C110.01 (EC| 2.7.11.1) Length = 1023 Score = 104 bits (259), Expect = 9e-23 Identities = 63/152 (41%), Positives = 86/152 (56%), Gaps = 15/152 (9%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P+I+++ + + T H IV++Y +GGELF+ I R + A F QL+SGV+Y HS Sbjct: 558 PHIVKYLDFVKTKHHFGIVLDYVNGGELFDYILARRRLEDSVACRLFAQLISGVAYLHSR 617 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYS------KSSVLHSQP-------KSTVGTPA 327 V HRDLKLEN LLD T + I DFG++ + HS P ++ G+P Sbjct: 618 GVVHRDLKLENILLD--TNRNIVIADFGFATTFGHFNTLSEHSLPTEKPDLFSTSCGSPC 675 Query: 328 YIAPEVLLKKE--YDGKIADVWSRGVTLYVML 417 Y APE++ K Y G AD+WS GV LY ML Sbjct: 676 YAAPELVNCKSGMYAGTQADIWSCGVILYAML 707
>CDPK1_PLAYO (Q7RAH3) Calcium-dependent protein kinase 1 (EC 2.7.11.1)| Length = 534 Score = 104 bits (259), Expect = 9e-23 Identities = 59/138 (42%), Positives = 84/138 (60%), Gaps = 1/138 (0%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PNII+ +V + +V E+ GGELFE+I N +F E +A +Q+LSG+ Y H Sbjct: 124 PNIIKLFDVFEDKKYFYLVTEFYEGGELFEQIINRHKFDECDAANIMKQILSGICYLHKH 183 Query: 187 QVCHRDLKLENTLLDG-STAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEY 363 + HRD+K EN LL+ ++ +KI DFG S + + +GT YIAPEV LKK+Y Sbjct: 184 NIVHRDIKPENILLENKNSLLNIKIVDFGLSSFFSKDYKLRDRLGTAYYIAPEV-LKKKY 242 Query: 364 DGKIADVWSRGVTLYVML 417 + K DVWS GV +Y++L Sbjct: 243 NEK-CDVWSCGVIMYILL 259
>DAPK3_RAT (O88764) Death-associated protein kinase 3 (EC 2.7.11.1) (DAP| kinase 3) (DAP-like kinase) (Dlk) (ZIP-kinase) Length = 448 Score = 104 bits (259), Expect = 9e-23 Identities = 56/139 (40%), Positives = 83/139 (59%), Gaps = 2/139 (1%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PNII +V T + +++E SGGELF+ + +EDEA F +Q+L GV Y HS Sbjct: 74 PNIITLHDVFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGVHYLHSK 133 Query: 187 QVCHRDLKLENTLL--DGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKE 360 ++ H DLK EN +L + +PR+K+ DFG + S+ K+ GTP ++APE+ + E Sbjct: 134 RIAHFDLKPENIMLLDKHAASPRIKLIDFGIAHRIEAGSEFKNIFGTPEFVAPEI-VNYE 192 Query: 361 YDGKIADVWSRGVTLYVML 417 G AD+WS GV Y++L Sbjct: 193 PLGLEADMWSIGVITYILL 211
>DAPK3_MOUSE (O54784) Death-associated protein kinase 3 (EC 2.7.11.1) (DAP| kinase 3) (DAP-like kinase) (Dlk) (ZIP-kinase) Length = 448 Score = 104 bits (259), Expect = 9e-23 Identities = 56/139 (40%), Positives = 83/139 (59%), Gaps = 2/139 (1%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PNII +V T + +++E SGGELF+ + +EDEA F +Q+L GV Y HS Sbjct: 74 PNIITLHDVFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGVHYLHSK 133 Query: 187 QVCHRDLKLENTLL--DGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKE 360 ++ H DLK EN +L + +PR+K+ DFG + S+ K+ GTP ++APE+ + E Sbjct: 134 RIAHFDLKPENIMLLDKHAASPRIKLIDFGIAHRIEAGSEFKNIFGTPEFVAPEI-VNYE 192 Query: 361 YDGKIADVWSRGVTLYVML 417 G AD+WS GV Y++L Sbjct: 193 PLGLEADMWSIGVITYILL 211
>KCC1G_HUMAN (Q96NX5) Calcium/calmodulin-dependent protein kinase type 1G (EC| 2.7.11.17) (CaM kinase IG) (CaM kinase I gamma) (CaMKI gamma) (CaMKI-gamma) (CaM-KI gamma) (CaMKIG) (CaMK-like CREB kinase III) (CLICK III) Length = 476 Score = 104 bits (259), Expect = 9e-23 Identities = 58/137 (42%), Positives = 79/137 (57%), Gaps = 1/137 (0%) Frame = +1 Query: 10 NIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSMQ 189 NI+ +++ + TH +VM+ SGGELF+RI G ++E +A QQ+LS V Y H Sbjct: 79 NIVTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKYLHENG 138 Query: 190 VCHRDLKLENTL-LDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 + HRDLK EN L L ++ I DFG SK + + GTP Y+APEVL +K Y Sbjct: 139 IVHRDLKPENLLYLTPEENSKIMITDFGLSKME-QNGIMSTACGTPGYVAPEVLAQKPY- 196 Query: 367 GKIADVWSRGVTLYVML 417 K D WS GV Y++L Sbjct: 197 SKAVDCWSIGVITYILL 213
>KPSH1_MOUSE (Q91YA2) Serine/threonine-protein kinase H1 (EC 2.7.11.1) (PSK-H1)| Length = 423 Score = 104 bits (259), Expect = 9e-23 Identities = 60/139 (43%), Positives = 83/139 (59%), Gaps = 3/139 (2%) Frame = +1 Query: 10 NIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSMQ 189 NII+ EV T + +VME A+GGELF+RI G F+E +A Q +L GV Y H++ Sbjct: 153 NIIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMVLDGVRYLHALG 212 Query: 190 VCHRDLKLENTL-LDGSTAPRLKICDFGYSKSSVLHSQ--PKSTVGTPAYIAPEVLLKKE 360 + HRDLK EN L T ++ I DFG + + K+T GTP YIAPEVL++K Sbjct: 213 ITHRDLKPENLLYYHPGTDSKIIITDFGLASARKKGDDCLMKTTCGTPEYIAPEVLVRKP 272 Query: 361 YDGKIADVWSRGVTLYVML 417 Y + D+W+ GV Y++L Sbjct: 273 YTNSV-DMWALGVIAYILL 290
>KPSH1_HUMAN (P11801) Serine/threonine-protein kinase H1 (EC 2.7.11.1) (PSK-H1)| Length = 423 Score = 104 bits (259), Expect = 9e-23 Identities = 60/139 (43%), Positives = 83/139 (59%), Gaps = 3/139 (2%) Frame = +1 Query: 10 NIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSMQ 189 NII+ EV T + +VME A+GGELF+RI G F+E +A Q +L GV Y H++ Sbjct: 153 NIIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMVLDGVRYLHALG 212 Query: 190 VCHRDLKLENTL-LDGSTAPRLKICDFGYSKSSVLHSQ--PKSTVGTPAYIAPEVLLKKE 360 + HRDLK EN L T ++ I DFG + + K+T GTP YIAPEVL++K Sbjct: 213 ITHRDLKPENLLYYHPGTDSKIIITDFGLASARKKGDDCLMKTTCGTPEYIAPEVLVRKP 272 Query: 361 YDGKIADVWSRGVTLYVML 417 Y + D+W+ GV Y++L Sbjct: 273 YTNSV-DMWALGVIAYILL 290
>KCC4_YEAST (P25389) Probable serine/threonine-protein kinase KCC4 (EC| 2.7.11.1) Length = 1037 Score = 103 bits (258), Expect = 1e-22 Identities = 54/137 (39%), Positives = 83/137 (60%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PN++ +V T +L +++EYA GELF + + G E EA F+Q++ G+SYCH++ Sbjct: 87 PNVLSLYDVWETNNNLYLILEYAEKGELFNLLVDHGPLPEREAINCFRQIIIGISYCHAL 146 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 + HRDLK EN LLD + +KI DFG + +++ G+P Y APE++ Y+ Sbjct: 147 GIVHRDLKPENLLLD--SFYNIKIADFGMAALQTDADLLETSCGSPHYAAPEIVSGLPYE 204 Query: 367 GKIADVWSRGVTLYVML 417 G +DVWS GV L+ +L Sbjct: 205 GFASDVWSCGVILFALL 221
>TSSK3_HUMAN (Q96PN8) Testis-specific serine/threonine-protein kinase 3 (EC| 2.7.11.1) (TSSK-3) (Testis-specific kinase 3) (TSK-3) (Serine/threonine-protein kinase 22C) Length = 268 Score = 103 bits (258), Expect = 1e-22 Identities = 60/139 (43%), Positives = 81/139 (58%), Gaps = 3/139 (2%) Frame = +1 Query: 10 NIIRFKEVILTPT-HLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 NII+ E++ + + +VME A GG++F+ + N G E A+ F+Q++ + YCH Sbjct: 69 NIIQVYEMLESADGKICLVMELAEGGDVFDCVLNGGPLPESRAKALFRQMVEAIRYCHGC 128 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSK-SSVLHSQPKST-VGTPAYIAPEVLLKKE 360 V HRDLK EN LL G LK+ DFG++K H + T G+ AY APEVL Sbjct: 129 GVAHRDLKCENALLQGF---NLKLTDFGFAKVLPKSHRELSQTFCGSTAYAAPEVLQGIP 185 Query: 361 YDGKIADVWSRGVTLYVML 417 +D K DVWS GV LYVML Sbjct: 186 HDSKKGDVWSMGVVLYVML 204
>SNRK_RAT (Q63553) SNF-related serine/threonine-protein kinase (EC 2.7.11.1)| (SNF1-related kinase) Length = 746 Score = 103 bits (258), Expect = 1e-22 Identities = 54/138 (39%), Positives = 82/138 (59%), Gaps = 1/138 (0%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGR-FSEDEARFFFQQLLSGVSYCHS 183 PNI+R EVI T T L +++E GG++F+ I +ED A+ +F Q++ +SYCH Sbjct: 73 PNIVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAISYCHK 132 Query: 184 MQVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEY 363 + V HRDLK EN + +K+ DFG+S + ++ G+ AY APE+LL EY Sbjct: 133 LHVVHRDLKPENVVFFEKQG-LVKLTDFGFSNKFQPGKKLTTSCGSLAYSAPEILLGDEY 191 Query: 364 DGKIADVWSRGVTLYVML 417 D D+WS GV L++++ Sbjct: 192 DAPAVDIWSLGVILFMLV 209
>SNRK_HUMAN (Q9NRH2) SNF-related serine/threonine-protein kinase (EC 2.7.11.1)| (SNF1-related kinase) Length = 765 Score = 103 bits (258), Expect = 1e-22 Identities = 54/138 (39%), Positives = 82/138 (59%), Gaps = 1/138 (0%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGR-FSEDEARFFFQQLLSGVSYCHS 183 PNI+R EVI T T L +++E GG++F+ I +ED A+ +F Q++ +SYCH Sbjct: 73 PNIVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAISYCHK 132 Query: 184 MQVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEY 363 + V HRDLK EN + +K+ DFG+S + ++ G+ AY APE+LL EY Sbjct: 133 LHVVHRDLKPENVVFFEKQG-LVKLTDFGFSNKFQPGKKLTTSCGSLAYSAPEILLGDEY 191 Query: 364 DGKIADVWSRGVTLYVML 417 D D+WS GV L++++ Sbjct: 192 DAPAVDIWSLGVILFMLV 209
>DAPK1_MOUSE (Q80YE7) Death-associated protein kinase 1 (EC 2.7.11.1) (DAP| kinase 1) Length = 1442 Score = 103 bits (258), Expect = 1e-22 Identities = 58/139 (41%), Positives = 85/139 (61%), Gaps = 2/139 (1%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PN+I EV T + +++E +GGELF+ + +E+EA F +Q+LSGV Y HS+ Sbjct: 74 PNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQILSGVYYLHSL 133 Query: 187 QVCHRDLKLEN-TLLDGST-APRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKE 360 Q+ H DLK EN LLD + PR+KI DFG + ++ K+ GTP ++APE+ + E Sbjct: 134 QIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHKIDFGNEFKNIFGTPEFVAPEI-VNYE 192 Query: 361 YDGKIADVWSRGVTLYVML 417 G AD+WS GV Y++L Sbjct: 193 PLGLEADMWSIGVITYILL 211
>SNRK_MOUSE (Q8VDU5) SNF-related serine/threonine-protein kinase (EC 2.7.11.1)| (SNF1-related kinase) Length = 748 Score = 103 bits (258), Expect = 1e-22 Identities = 54/138 (39%), Positives = 82/138 (59%), Gaps = 1/138 (0%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGR-FSEDEARFFFQQLLSGVSYCHS 183 PNI+R EVI T T L +++E GG++F+ I +ED A+ +F Q++ +SYCH Sbjct: 73 PNIVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAISYCHK 132 Query: 184 MQVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEY 363 + V HRDLK EN + +K+ DFG+S + ++ G+ AY APE+LL EY Sbjct: 133 LHVVHRDLKPENVVFFEKQG-LVKLTDFGFSNKFQPGKKLTTSCGSLAYSAPEILLGDEY 191 Query: 364 DGKIADVWSRGVTLYVML 417 D D+WS GV L++++ Sbjct: 192 DAPAVDIWSLGVILFMLV 209
>SCH9_YEAST (P11792) Serine/threonine-protein kinase SCH9 (EC 2.7.11.1)| Length = 823 Score = 103 bits (257), Expect = 2e-22 Identities = 56/136 (41%), Positives = 80/136 (58%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P I+ K TPT L +V +Y SGGELF + GRFSED A+F+ +L+ + + H Sbjct: 472 PFIVGLKFSFQTPTDLYLVTDYMSGGELFWHLQKEGRFSEDRAKFYIAELVLALEHLHDN 531 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 + +RDLK EN LLD + + +CDFG SK+ L + + GT Y+APE+LL + Sbjct: 532 DIVYRDLKPENILLDAN--GNIALCDFGLSKAD-LKDRTNTFCGTTEYLAPELLLDETGY 588 Query: 367 GKIADVWSRGVTLYVM 414 K+ D WS GV ++ M Sbjct: 589 TKMVDFWSLGVLIFEM 604
>KCC1A_RAT (Q63450) Calcium/calmodulin-dependent protein kinase type 1 (EC| 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha) Length = 374 Score = 102 bits (255), Expect = 3e-22 Identities = 58/140 (41%), Positives = 80/140 (57%), Gaps = 3/140 (2%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PNI+ ++ + HL ++M+ SGGELF+RI G ++E +A Q+L V Y H + Sbjct: 76 PNIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDL 135 Query: 187 QVCHRDLKLENTL---LDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKK 357 + HRDLK EN L LD + ++ I DFG SK S + GTP Y+APEVL +K Sbjct: 136 GIVHRDLKPENLLYYSLDEDS--KIMISDFGLSKMEDPGSVLSTACGTPGYVAPEVLAQK 193 Query: 358 EYDGKIADVWSRGVTLYVML 417 Y K D WS GV Y++L Sbjct: 194 PY-SKAVDCWSIGVIAYILL 212
>KCC1A_MOUSE (Q91YS8) Calcium/calmodulin-dependent protein kinase type 1 (EC| 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha) Length = 374 Score = 102 bits (255), Expect = 3e-22 Identities = 58/140 (41%), Positives = 80/140 (57%), Gaps = 3/140 (2%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PNI+ ++ + HL ++M+ SGGELF+RI G ++E +A Q+L V Y H + Sbjct: 76 PNIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDL 135 Query: 187 QVCHRDLKLENTL---LDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKK 357 + HRDLK EN L LD + ++ I DFG SK S + GTP Y+APEVL +K Sbjct: 136 GIVHRDLKPENLLYYSLDEDS--KIMISDFGLSKMEDPGSVLSTACGTPGYVAPEVLAQK 193 Query: 358 EYDGKIADVWSRGVTLYVML 417 Y K D WS GV Y++L Sbjct: 194 PY-SKAVDCWSIGVIAYILL 212
>KCC1A_HUMAN (Q14012) Calcium/calmodulin-dependent protein kinase type 1 (EC| 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha) Length = 370 Score = 102 bits (255), Expect = 3e-22 Identities = 58/140 (41%), Positives = 80/140 (57%), Gaps = 3/140 (2%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PNI+ ++ + HL ++M+ SGGELF+RI G ++E +A Q+L V Y H + Sbjct: 76 PNIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDL 135 Query: 187 QVCHRDLKLENTL---LDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKK 357 + HRDLK EN L LD + ++ I DFG SK S + GTP Y+APEVL +K Sbjct: 136 GIVHRDLKPENLLYYSLDEDS--KIMISDFGLSKMEDPGSVLSTACGTPGYVAPEVLAQK 193 Query: 358 EYDGKIADVWSRGVTLYVML 417 Y K D WS GV Y++L Sbjct: 194 PY-SKAVDCWSIGVIAYILL 212
>TSSK3_MOUSE (Q9D2E1) Testis-specific serine/threonine-protein kinase 3 (EC| 2.7.11.1) (TSSK-3) (Testis-specific kinase 3) (TSK-3) (Serine/threonine-protein kinase 22C) Length = 268 Score = 102 bits (255), Expect = 3e-22 Identities = 58/139 (41%), Positives = 80/139 (57%), Gaps = 3/139 (2%) Frame = +1 Query: 10 NIIRFKEVILTPT-HLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 NII+ E++ + + +VME A GG++F+ + N G E A+ F+Q++ + YCH Sbjct: 69 NIIQVYEMLESADGKIYLVMELAEGGDVFDCVLNGGPLPESRAKALFRQMVEAIRYCHGC 128 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSK--SSVLHSQPKSTVGTPAYIAPEVLLKKE 360 V HRDLK EN LL G LK+ DFG++K ++ G+ AY APEVL Sbjct: 129 GVAHRDLKCENALLQGF---NLKLTDFGFAKVLPKSRRELSQTFCGSTAYAAPEVLQGIP 185 Query: 361 YDGKIADVWSRGVTLYVML 417 +D K DVWS GV LYVML Sbjct: 186 HDSKKGDVWSMGVVLYVML 204
>DAPK1_HUMAN (P53355) Death-associated protein kinase 1 (EC 2.7.11.1) (DAP| kinase 1) Length = 1432 Score = 102 bits (255), Expect = 3e-22 Identities = 57/139 (41%), Positives = 85/139 (61%), Gaps = 2/139 (1%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PN+I EV T + +++E +GGELF+ + +E+EA F +Q+L+GV Y HS+ Sbjct: 74 PNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQILNGVYYLHSL 133 Query: 187 QVCHRDLKLEN-TLLDGST-APRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKE 360 Q+ H DLK EN LLD + PR+KI DFG + ++ K+ GTP ++APE+ + E Sbjct: 134 QIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHKIDFGNEFKNIFGTPEFVAPEI-VNYE 192 Query: 361 YDGKIADVWSRGVTLYVML 417 G AD+WS GV Y++L Sbjct: 193 PLGLEADMWSIGVITYILL 211
>AKT2_RAT (P47197) RAC-beta serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta) Length = 481 Score = 102 bits (255), Expect = 3e-22 Identities = 57/138 (41%), Positives = 79/138 (57%), Gaps = 1/138 (0%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P + K T L VMEYA+GG+LF + F+ED ARF+ +++S + Y HS Sbjct: 210 PFLTALKYAFQTHDRLCFVMEYANGGDLFFHLSRERVFTEDRARFYGAEIVSALEYLHST 269 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLH-SQPKSTVGTPAYIAPEVLLKKEY 363 V +RD+KLEN +LD +KI DFG SK + + K+ GTP Y+APEVL +Y Sbjct: 270 DVVYRDIKLENLMLDKD--GHIKITDFGLSKEGISDGATMKTFCGTPEYLAPEVLEDNDY 327 Query: 364 DGKIADVWSRGVTLYVML 417 G+ D W GV +Y M+ Sbjct: 328 -GRAVDWWGLGVVMYEMM 344
>AKT1_DROME (Q8INB9) RAC serine/threonine-protein kinase (EC 2.7.11.1)| (DRAC-PK) (Akt) (Dakt1) (Protein kinase B) (PKB) Length = 611 Score = 102 bits (254), Expect = 4e-22 Identities = 55/138 (39%), Positives = 79/138 (57%), Gaps = 1/138 (0%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P +I K T L VM+Y +GGELF + + F+ED RF+ +++S + Y HS Sbjct: 324 PFLISLKYSFQTNDRLCFVMQYVNGGELFWHLSHERIFTEDRTRFYGAEIISALGYLHSQ 383 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQ-PKSTVGTPAYIAPEVLLKKEY 363 + +RDLKLEN LLD +K+ DFG K + + + K+ GTP Y+APEVL +Y Sbjct: 384 GIIYRDLKLENLLLDKD--GHIKVADFGLCKEDITYGRTTKTFCGTPEYLAPEVLDDNDY 441 Query: 364 DGKIADVWSRGVTLYVML 417 G+ D W GV +Y M+ Sbjct: 442 -GQAVDWWGTGVVMYEMI 458
>MELK_MOUSE (Q61846) Maternal embryonic leucine zipper kinase (EC 2.7.11.1)| (Protein kinase PK38) (mPK38) Length = 643 Score = 102 bits (254), Expect = 4e-22 Identities = 60/144 (41%), Positives = 84/144 (58%), Gaps = 8/144 (5%) Frame = +1 Query: 10 NIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSMQ 189 +I + V+ T + +V+EY GGELF+ I + R SE+E R F+Q+LS V+Y HS Sbjct: 68 HICQLYHVLETKNKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQILSAVAYVHSQG 127 Query: 190 VCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPK--------STVGTPAYIAPEV 345 HRDLK EN L D + +LK+ DFG L ++PK + G+ AY APE+ Sbjct: 128 YAHRDLKPENLLFDEN--HKLKLIDFG------LCAKPKGNKDYHLQTCCGSLAYAAPEL 179 Query: 346 LLKKEYDGKIADVWSRGVTLYVML 417 + K Y G ADVWS G+ LYV++ Sbjct: 180 IQGKSYLGSEADVWSMGILLYVLM 203
>KPC1_APLCA (Q16974) Calcium-dependent protein kinase C (EC 2.7.11.13) (APL I)| Length = 649 Score = 102 bits (253), Expect = 5e-22 Identities = 55/139 (39%), Positives = 80/139 (57%), Gaps = 1/139 (0%) Frame = +1 Query: 4 PPNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHS 183 PP +++ T L VMEY +GG+L RI G+F E A F+ ++ G+ Y H+ Sbjct: 378 PPFLVQLHSCFQTMDRLYFVMEYVNGGDLMYRIQQEGKFKEPVAAFYAAEIAIGLFYLHT 437 Query: 184 MQVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKST-VGTPAYIAPEVLLKKE 360 + +RDLKL+N +LD +KI DFG K +++ + T GTP YIAPE++L + Sbjct: 438 QGIVYRDLKLDNVMLDAE--GHIKIADFGMCKENIMGDKTTRTFCGTPDYIAPEIVLYQP 495 Query: 361 YDGKIADVWSRGVTLYVML 417 Y G+ D W+ GV LY ML Sbjct: 496 Y-GRSVDWWAYGVLLYEML 513
>AKT2A_XENLA (Q7ZX15) RAC-beta serine/threonine-protein kinase-A (EC 2.7.11.1)| (RAC-PK-beta-A) (Protein kinase Akt-2-A) (Protein kinase B, beta-A) (PKB beta-A) Length = 486 Score = 102 bits (253), Expect = 5e-22 Identities = 57/138 (41%), Positives = 76/138 (55%), Gaps = 1/138 (0%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P + K T L VMEYA+GGELF + F+ED ARF+ +++S + Y HS Sbjct: 215 PFLTALKYAFQTSDRLCFVMEYANGGELFFHLSRERVFTEDRARFYGAEIVSALEYLHSR 274 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKST-VGTPAYIAPEVLLKKEY 363 V +RD+KLEN +LD +KI DFG K + T GTP Y+APEVL +Y Sbjct: 275 NVVYRDIKLENLMLDKD--GHVKITDFGLCKEGITDGATMRTFCGTPEYLAPEVLEDNDY 332 Query: 364 DGKIADVWSRGVTLYVML 417 G+ D W GV +Y M+ Sbjct: 333 -GRAVDWWGLGVVMYEMM 349
>AKT2_MOUSE (Q60823) RAC-beta serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta) Length = 481 Score = 102 bits (253), Expect = 5e-22 Identities = 57/138 (41%), Positives = 78/138 (56%), Gaps = 1/138 (0%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P + K T L VMEYA+GGELF + F+ED ARF+ +++S + Y HS Sbjct: 210 PFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEDRARFYGAEIVSALEYLHSR 269 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLH-SQPKSTVGTPAYIAPEVLLKKEY 363 V +RD+KLEN +LD +KI DFG K + + K+ GTP Y+APEVL +Y Sbjct: 270 DVVYRDIKLENLMLDKD--GHIKITDFGLCKEGISDGATMKTFCGTPEYLAPEVLEDNDY 327 Query: 364 DGKIADVWSRGVTLYVML 417 G+ D W GV +Y M+ Sbjct: 328 -GRAVDWWGLGVVMYEMM 344
>DAPK3_HUMAN (O43293) Death-associated protein kinase 3 (EC 2.7.11.1) (DAP| kinase 3) (DAP-like kinase) (Dlk) (ZIP-kinase) Length = 454 Score = 101 bits (252), Expect = 6e-22 Identities = 54/139 (38%), Positives = 81/139 (58%), Gaps = 2/139 (1%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PNII ++ T + +++E SGGELF+ + +EDEA F +Q+L GV Y HS Sbjct: 74 PNIITLHDIFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGVHYLHSK 133 Query: 187 QVCHRDLKLENTLLDGSTA--PRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKE 360 ++ H DLK EN +L PR+K+ DFG + ++ K+ GTP ++APE+ + E Sbjct: 134 RIAHFDLKPENIMLLDKNVPNPRIKLIDFGIAHKIEAGNEFKNIFGTPEFVAPEI-VNYE 192 Query: 361 YDGKIADVWSRGVTLYVML 417 G AD+WS GV Y++L Sbjct: 193 PLGLEADMWSIGVITYILL 211
>AKT2B_XENLA (Q6IP76) RAC-beta serine/threonine-protein kinase-B (EC 2.7.11.1)| (RAC-PK-beta-B) (Protein kinase Akt-2-B) (Protein kinase B, beta-B) (PKB beta-B) Length = 485 Score = 101 bits (252), Expect = 6e-22 Identities = 57/138 (41%), Positives = 76/138 (55%), Gaps = 1/138 (0%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P + K T L VMEYA+GGELF + F+ED ARF+ +++S + Y HS Sbjct: 214 PFLTGLKYAFQTSDRLCFVMEYANGGELFFHLSRERVFTEDRARFYGAEIVSALEYLHSR 273 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKST-VGTPAYIAPEVLLKKEY 363 V +RD+KLEN +LD +KI DFG K + T GTP Y+APEVL +Y Sbjct: 274 NVVYRDIKLENLMLDKD--GHVKITDFGLCKEGITDGATMRTFCGTPEYLAPEVLEDNDY 331 Query: 364 DGKIADVWSRGVTLYVML 417 G+ D W GV +Y M+ Sbjct: 332 -GRAVDWWGLGVVMYEMM 348
>YP150_YEAST (Q12152) Putative serine/threonine-protein kinase YPL150W (EC| 2.7.11.1) Length = 901 Score = 101 bits (251), Expect = 8e-22 Identities = 52/137 (37%), Positives = 80/137 (58%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P I + EVI+T + + + +EY G EL++ + + R S E F Q+ V Y HSM Sbjct: 92 PYITKLYEVIVTESKVWMALEYCPGKELYDHLLSLRRISLLECGELFAQISGAVYYAHSM 151 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 HRDLKLEN LLD + K+ DFG+++ + + ++ GT Y+APE++ ++ YD Sbjct: 152 HCVHRDLKLENILLDKN--GNAKLTDFGFTRECMTKTTLETVCGTTVYMAPELIERRTYD 209 Query: 367 GKIADVWSRGVTLYVML 417 G D+WS GV LY ++ Sbjct: 210 GFKIDIWSLGVILYTLI 226
>KPC4_DROME (P83099) Putative protein kinase C, delta type homolog (EC| 2.7.11.13) Length = 643 Score = 101 bits (251), Expect = 8e-22 Identities = 55/127 (43%), Positives = 79/127 (62%), Gaps = 1/127 (0%) Frame = +1 Query: 40 TPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSMQVCHRDLKLEN 219 T +HL VMEY +GG+L I +GRFSE+ ARF+ +++SG+ + H + +RDLKL+N Sbjct: 385 TESHLFFVMEYLNGGDLMFHIQESGRFSEERARFYGAEIISGLKFLHKKGIIYRDLKLDN 444 Query: 220 TLLDGSTAPRLKICDFGYSKSSV-LHSQPKSTVGTPAYIAPEVLLKKEYDGKIADVWSRG 396 LLD ++I DFG K + L S GTP Y+APE++ ++Y+ + D WS G Sbjct: 445 VLLD--YEGHVRIADFGMCKLQIYLDKTADSFCGTPDYMAPEIIKGEKYNQNV-DWWSFG 501 Query: 397 VTLYVML 417 V LY ML Sbjct: 502 VLLYEML 508
>KAPCG_HUMAN (P22612) cAMP-dependent protein kinase, gamma-catalytic subunit (EC| 2.7.11.11) (PKA C-gamma) Length = 350 Score = 101 bits (251), Expect = 8e-22 Identities = 54/136 (39%), Positives = 82/136 (60%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P +++ + ++L +VMEY GGE+F R+ GRFSE A F+ Q++ V Y HS+ Sbjct: 101 PFLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLHSL 160 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 + HRDLK EN L+D L++ DFG++K + + + GTP Y+APE++L K Y+ Sbjct: 161 DLIHRDLKPENLLID--QQGYLQVTDFGFAKR--VKGRTWTLCGTPEYLAPEIILSKGYN 216 Query: 367 GKIADVWSRGVTLYVM 414 K D W+ GV +Y M Sbjct: 217 -KAVDWWALGVLIYEM 231
>CDR1_SCHPO (P07334) Mitosis inducer protein kinase cdr1 (EC 2.7.11.1) (Protein| kinase nim1) Length = 593 Score = 100 bits (250), Expect = 1e-21 Identities = 56/137 (40%), Positives = 77/137 (56%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PNI+R +V H+ + +EY GELF I G SE EA + Q+L V++CH Sbjct: 63 PNILRLYDVWTDHQHMYLALEYVPDGELFHYIRKHGPLSEREAAHYLSQILDAVAHCHRF 122 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 + HRDLKLEN L+ ++KI DFG + S ++ G+ Y+APE++ K Y Sbjct: 123 RFRHRDLKLENILIK-VNEQQIKIADFGMATVEPNDSCLENYCGSLHYLAPEIVSHKPYR 181 Query: 367 GKIADVWSRGVTLYVML 417 G ADVWS GV LY +L Sbjct: 182 GAPADVWSCGVILYSLL 198
>AKT1_BOVIN (Q01314) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (Protein kinase B) (PKB) Length = 480 Score = 100 bits (250), Expect = 1e-21 Identities = 59/139 (42%), Positives = 80/139 (57%), Gaps = 2/139 (1%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHS- 183 P++ K T L VMEYA+GGELF + FSED ARF+ +++S + Y HS Sbjct: 208 PSLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSE 267 Query: 184 MQVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLH-SQPKSTVGTPAYIAPEVLLKKE 360 +V +RDLKLEN +LD +KI DFG K + + K+ GTP Y+APEVL + Sbjct: 268 KEVVYRDLKLENLMLDKD--GHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLEDND 325 Query: 361 YDGKIADVWSRGVTLYVML 417 Y G+ D W GV +Y M+ Sbjct: 326 Y-GRAVDWWGLGVVMYEMM 343
>AKT3_RAT (Q63484) RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-gamma) (Protein kinase Akt-3) (Protein kinase B, gamma) (PKB gamma) Length = 454 Score = 100 bits (249), Expect = 1e-21 Identities = 56/138 (40%), Positives = 77/138 (55%), Gaps = 1/138 (0%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P + K T L VMEY +GGELF + FSED RF+ +++S + Y HS Sbjct: 206 PFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSG 265 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQP-KSTVGTPAYIAPEVLLKKEY 363 ++ +RDLKLEN +LD +KI DFG K + + K+ GTP Y+APEVL +Y Sbjct: 266 KIVYRDLKLENLMLDKD--GHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDY 323 Query: 364 DGKIADVWSRGVTLYVML 417 G+ D W GV +Y M+ Sbjct: 324 -GRAVDWWGLGVVMYEMM 340
>TSSK2_HUMAN (Q96PF2) Testis-specific serine/threonine-protein kinase 2 (EC| 2.7.11.1) (TSSK-2) (Testis-specific kinase 2) (TSK-2) (Serine/threonine-protein kinase 22B) (DiGeorge syndrome protein G) Length = 358 Score = 100 bits (249), Expect = 1e-21 Identities = 60/142 (42%), Positives = 79/142 (55%), Gaps = 6/142 (4%) Frame = +1 Query: 10 NIIRFKEVILTPT-HLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 +II+ E+ T + I+ME G+L E I G ED AR F+QL S V YCH + Sbjct: 71 SIIKTYEIFETSDGRIYIIMELGVQGDLLEFIKCQGALHEDVARKMFRQLSSAVKYCHDL 130 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQ-----PKSTVGTPAYIAPEVLL 351 + HRDLK EN LLD +K+ DFG+SK + S K+ G+ AY APEVL Sbjct: 131 DIVHRDLKCENLLLDKDF--NIKLSDFGFSKRCLRDSNGRIILSKTFCGSAAYAAPEVLQ 188 Query: 352 KKEYDGKIADVWSRGVTLYVML 417 Y K+ D+WS GV LY+M+ Sbjct: 189 SIPYQPKVYDIWSLGVILYIMV 210
>MELK_HUMAN (Q14680) Maternal embryonic leucine zipper kinase (EC 2.7.11.1)| (hMELK) (Protein kinase PK38) (hPK38) Length = 651 Score = 100 bits (249), Expect = 1e-21 Identities = 59/144 (40%), Positives = 83/144 (57%), Gaps = 8/144 (5%) Frame = +1 Query: 10 NIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSMQ 189 +I + V+ T + +V+EY GGELF+ I + R SE+E R F+Q++S V+Y HS Sbjct: 68 HICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQG 127 Query: 190 VCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPK--------STVGTPAYIAPEV 345 HRDLK EN L D +LK+ DFG L ++PK + G+ AY APE+ Sbjct: 128 YAHRDLKPENLLFD--EYHKLKLIDFG------LCAKPKGNKDYHLQTCCGSLAYAAPEL 179 Query: 346 LLKKEYDGKIADVWSRGVTLYVML 417 + K Y G ADVWS G+ LYV++ Sbjct: 180 IQGKSYLGSEADVWSMGILLYVLM 203
>AKT2_HUMAN (P31751) RAC-beta serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta) Length = 481 Score = 100 bits (249), Expect = 1e-21 Identities = 56/138 (40%), Positives = 78/138 (56%), Gaps = 1/138 (0%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P + K T L VMEYA+GGELF + F+E+ ARF+ +++S + Y HS Sbjct: 210 PFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEIVSALEYLHSR 269 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLH-SQPKSTVGTPAYIAPEVLLKKEY 363 V +RD+KLEN +LD +KI DFG K + + K+ GTP Y+APEVL +Y Sbjct: 270 DVVYRDIKLENLMLDKD--GHIKITDFGLCKEGISDGATMKTFCGTPEYLAPEVLEDNDY 327 Query: 364 DGKIADVWSRGVTLYVML 417 G+ D W GV +Y M+ Sbjct: 328 -GRAVDWWGLGVVMYEMM 344
>AKT3_MOUSE (Q9WUA6) RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-gamma) (Protein kinase Akt-3) (Protein kinase B, gamma) (PKB gamma) Length = 479 Score = 100 bits (249), Expect = 1e-21 Identities = 56/138 (40%), Positives = 77/138 (55%), Gaps = 1/138 (0%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P + K T L VMEY +GGELF + FSED RF+ +++S + Y HS Sbjct: 206 PFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSG 265 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQP-KSTVGTPAYIAPEVLLKKEY 363 ++ +RDLKLEN +LD +KI DFG K + + K+ GTP Y+APEVL +Y Sbjct: 266 KIVYRDLKLENLMLDKD--GHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDY 323 Query: 364 DGKIADVWSRGVTLYVML 417 G+ D W GV +Y M+ Sbjct: 324 -GRAVDWWGLGVVMYEMM 340
>AKT3_HUMAN (Q9Y243) RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-gamma) (Protein kinase Akt-3) (Protein kinase B, gamma) (PKB gamma) (STK-2) Length = 479 Score = 100 bits (249), Expect = 1e-21 Identities = 56/138 (40%), Positives = 77/138 (55%), Gaps = 1/138 (0%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P + K T L VMEY +GGELF + FSED RF+ +++S + Y HS Sbjct: 206 PFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSG 265 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQP-KSTVGTPAYIAPEVLLKKEY 363 ++ +RDLKLEN +LD +KI DFG K + + K+ GTP Y+APEVL +Y Sbjct: 266 KIVYRDLKLENLMLDKD--GHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDY 323 Query: 364 DGKIADVWSRGVTLYVML 417 G+ D W GV +Y M+ Sbjct: 324 -GRAVDWWGLGVVMYEMM 340
>STK33_HUMAN (Q9BYT3) Serine/threonine-protein kinase 33 (EC 2.7.11.1)| Length = 514 Score = 100 bits (248), Expect = 2e-21 Identities = 55/145 (37%), Positives = 83/145 (57%), Gaps = 9/145 (6%) Frame = +1 Query: 10 NIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSMQ 189 +II ++V TP + +VME GEL E + G FSE+E R+ Q L S ++Y H+ Sbjct: 174 HIIHLEQVFETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHNND 233 Query: 190 VCHRDLKLENTLLDGSTAP-------RLKICDFGYS--KSSVLHSQPKSTVGTPAYIAPE 342 + HRDLKLEN ++ S +K+ DFG + K S + ++T GTP Y+APE Sbjct: 234 IVHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQATCGTPIYMAPE 293 Query: 343 VLLKKEYDGKIADVWSRGVTLYVML 417 V+ +Y + D+WS GV +Y++L Sbjct: 294 VISAHDYSQQ-CDIWSIGVVMYMLL 317
>KPC1_DROME (P05130) Protein kinase C, brain isozyme (EC 2.7.11.13) (PKC)| (dPKC53E(BR)) Length = 679 Score = 100 bits (248), Expect = 2e-21 Identities = 55/139 (39%), Positives = 82/139 (58%), Gaps = 1/139 (0%) Frame = +1 Query: 4 PPNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHS 183 PP +++ T L VMEY +GG+L +I G+F E A F+ ++ +G+ + H+ Sbjct: 408 PPFLVQLHSCFQTMDRLFFVMEYVNGGDLMFQIQQFGKFKEPVAVFYAAEIAAGLFFLHT 467 Query: 184 MQVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQ-PKSTVGTPAYIAPEVLLKKE 360 + +RDLKL+N LLD +KI DFG K +++ + K+ GTP YIAPE++L + Sbjct: 468 KGILYRDLKLDNVLLDAD--GHVKIADFGMCKENIVGDKTTKTFCGTPDYIAPEIILYQP 525 Query: 361 YDGKIADVWSRGVTLYVML 417 Y GK D W+ GV LY ML Sbjct: 526 Y-GKSVDWWAYGVLLYEML 543
>CDPK2_PLAF7 (Q8ICR0) Calcium-dependent protein kinase 2 (EC 2.7.11.1) (PfCDPK2)| Length = 508 Score = 99.8 bits (247), Expect = 2e-21 Identities = 56/138 (40%), Positives = 76/138 (55%), Gaps = 1/138 (0%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PNI++ E ++ ++ME SG ELF+ I G F+E A +Q+ S + Y HS+ Sbjct: 126 PNIVKLYETYENDNYIYLIMELCSGRELFDSIIENGSFTEKNAATIMKQIFSAIFYLHSL 185 Query: 187 QVCHRDLKLENTLLDGSTAPR-LKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEY 363 + HRDLK EN L LKI DFG SK+ + GTP Y+AP+VL K Y Sbjct: 186 NIVHRDLKPENFLFQSENKDSLLKIIDFGLSKNLGTGEFTTTKAGTPYYVAPQVLDGK-Y 244 Query: 364 DGKIADVWSRGVTLYVML 417 D K D+WS GV +Y +L Sbjct: 245 DKK-CDIWSSGVIMYTLL 261
>CDPK2_PLAFK (O15865) Calcium-dependent protein kinase 2 (EC 2.7.11.1) (PfCDPK2)| Length = 512 Score = 99.8 bits (247), Expect = 2e-21 Identities = 56/138 (40%), Positives = 76/138 (55%), Gaps = 1/138 (0%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PNI++ E ++ ++ME SG ELF+ I G F+E A +Q+ S + Y HS+ Sbjct: 126 PNIVKLYETYENDNYIYLIMELCSGRELFDSIIENGSFTEKNAATIMKQIFSAIFYLHSL 185 Query: 187 QVCHRDLKLENTLLDGSTAPR-LKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEY 363 + HRDLK EN L LKI DFG SK+ + GTP Y+AP+VL K Y Sbjct: 186 NIVHRDLKPENFLFQSENKDSLLKIIDFGLSKNLGTGEFTTTKAGTPYYVAPQVLDGK-Y 244 Query: 364 DGKIADVWSRGVTLYVML 417 D K D+WS GV +Y +L Sbjct: 245 DKK-CDIWSSGVIMYTLL 261
>TSSK1_MOUSE (Q61241) Testis-specific serine/threonine-protein kinase 1 (EC| 2.7.11.1) (TSSK-1) (Testis-specific kinase 1) (TSK-1) (Serine/threonine-protein kinase 22A) Length = 364 Score = 99.4 bits (246), Expect = 3e-21 Identities = 59/142 (41%), Positives = 78/142 (54%), Gaps = 6/142 (4%) Frame = +1 Query: 10 NIIRFKEVILTPT-HLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 +I++ E+ T + IVME G+L E I G ED+AR F QL S + YCH + Sbjct: 71 SIVKTYEIFATSDGKVYIVMELGVQGDLLEFIKTRGALQEDDARKKFHQLSSAIKYCHDL 130 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQ-----PKSTVGTPAYIAPEVLL 351 V HRDLK EN LLD +K+ DFG+SK + K+ G+ AY APEVL Sbjct: 131 DVVHRDLKSENLLLDKDF--NIKLSDFGFSKRCLRDDSGRLILSKTFCGSAAYAAPEVLQ 188 Query: 352 KKEYDGKIADVWSRGVTLYVML 417 Y K+ D+WS GV LY+M+ Sbjct: 189 GIPYQPKVYDIWSLGVILYIMV 210
>TSSK1_HUMAN (Q9BXA7) Testis-specific serine/threonine-protein kinase 1 (EC| 2.7.11.1) (TSSK-1) (Testis-specific kinase 1) (TSK-1) (Serine/threonine-protein kinase 22A) Length = 367 Score = 99.0 bits (245), Expect = 4e-21 Identities = 57/125 (45%), Positives = 71/125 (56%), Gaps = 5/125 (4%) Frame = +1 Query: 58 IVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSMQVCHRDLKLENTLLDGS 237 IVME A G+L E I G EDEAR F QL + YCH + V HRDLK +N LLD Sbjct: 88 IVMELAVQGDLLELIKTRGALHEDEARKKFHQLSLAIKYCHDLDVVHRDLKCDNLLLDKD 147 Query: 238 TAPRLKICDFGYSK-----SSVLHSQPKSTVGTPAYIAPEVLLKKEYDGKIADVWSRGVT 402 +K+ DF +SK S + K+ G+PAY APEVL Y K+ D+WS GV Sbjct: 148 F--NIKLSDFSFSKRCLRDDSGRMALSKTFCGSPAYAAPEVLQGIPYQPKVYDIWSLGVI 205 Query: 403 LYVML 417 LY+M+ Sbjct: 206 LYIMV 210
>AKT_MLVAT (P31748) AKT kinase transforming protein (EC 2.7.11.1)| Length = 501 Score = 98.6 bits (244), Expect = 5e-21 Identities = 59/139 (42%), Positives = 78/139 (56%), Gaps = 2/139 (1%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHS- 183 P + K T L VMEYA+GGELF + FSED ARF+ +++S + Y HS Sbjct: 229 PFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSE 288 Query: 184 MQVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLH-SQPKSTVGTPAYIAPEVLLKKE 360 V +RDLKLEN +LD +KI DFG K + + K+ GTP Y+APEVL + Sbjct: 289 KNVVYRDLKLENLMLDKD--GHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLEDND 346 Query: 361 YDGKIADVWSRGVTLYVML 417 Y G+ D W GV +Y M+ Sbjct: 347 Y-GRAVDWWGLGVVMYEMM 364
>CDPK_DAUCA (P28582) Calcium-dependent protein kinase (EC 2.7.11.1) (CDPK)| Length = 532 Score = 98.6 bits (244), Expect = 5e-21 Identities = 60/138 (43%), Positives = 79/138 (57%), Gaps = 1/138 (0%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PNI+ FK V + +VME +GGELF+RI G +SE A +Q+++ V CH M Sbjct: 140 PNIVEFKGVFEDRQSVHLVMELCAGGELFDRIIAQGHYSERAAATICRQIVNVVHVCHFM 199 Query: 187 QVCHRDLKLENTLLDGSTA-PRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEY 363 V HRDLK EN LL LK DFG S ++ VG+ Y+APEV L++ Y Sbjct: 200 GVMHRDLKPENFLLSSKDKDAMLKATDFGLSVFIEEGKVYRNIVGSAYYVAPEV-LRRSY 258 Query: 364 DGKIADVWSRGVTLYVML 417 GK D+WS GV LY++L Sbjct: 259 -GKEIDIWSAGVILYILL 275
>AKT1_RAT (P47196) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (Protein kinase B) (PKB) Length = 480 Score = 98.6 bits (244), Expect = 5e-21 Identities = 59/139 (42%), Positives = 78/139 (56%), Gaps = 2/139 (1%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHS- 183 P + K T L VMEYA+GGELF + FSED ARF+ +++S + Y HS Sbjct: 208 PFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSE 267 Query: 184 MQVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLH-SQPKSTVGTPAYIAPEVLLKKE 360 V +RDLKLEN +LD +KI DFG K + + K+ GTP Y+APEVL + Sbjct: 268 KNVVYRDLKLENLMLDKD--GHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLEDND 325 Query: 361 YDGKIADVWSRGVTLYVML 417 Y G+ D W GV +Y M+ Sbjct: 326 Y-GRAVDWWGLGVVMYEMM 343
>AKT1_MOUSE (P31750) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (AKT1 kinase) (Protein kinase B) (PKB) (C-AKT) (Thymoma viral proto-oncogene) Length = 480 Score = 98.6 bits (244), Expect = 5e-21 Identities = 59/139 (42%), Positives = 78/139 (56%), Gaps = 2/139 (1%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHS- 183 P + K T L VMEYA+GGELF + FSED ARF+ +++S + Y HS Sbjct: 208 PFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSE 267 Query: 184 MQVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLH-SQPKSTVGTPAYIAPEVLLKKE 360 V +RDLKLEN +LD +KI DFG K + + K+ GTP Y+APEVL + Sbjct: 268 KNVVYRDLKLENLMLDKD--GHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLEDND 325 Query: 361 YDGKIADVWSRGVTLYVML 417 Y G+ D W GV +Y M+ Sbjct: 326 Y-GRAVDWWGLGVVMYEMM 343
>AKT1_HUMAN (P31749) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (Protein kinase B) (PKB) (C-AKT) Length = 480 Score = 98.6 bits (244), Expect = 5e-21 Identities = 59/139 (42%), Positives = 78/139 (56%), Gaps = 2/139 (1%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHS- 183 P + K T L VMEYA+GGELF + FSED ARF+ +++S + Y HS Sbjct: 208 PFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSE 267 Query: 184 MQVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLH-SQPKSTVGTPAYIAPEVLLKKE 360 V +RDLKLEN +LD +KI DFG K + + K+ GTP Y+APEVL + Sbjct: 268 KNVVYRDLKLENLMLDKD--GHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLEDND 325 Query: 361 YDGKIADVWSRGVTLYVML 417 Y G+ D W GV +Y M+ Sbjct: 326 Y-GRAVDWWGLGVVMYEMM 343
>AKT1_XENLA (Q98TY9) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (Protein kinase Akt-1) (Protein kinase B, alpha) (PKB alpha) (xAkt) Length = 481 Score = 98.6 bits (244), Expect = 5e-21 Identities = 59/139 (42%), Positives = 78/139 (56%), Gaps = 2/139 (1%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHS- 183 P + K T L VMEYA+GGELF + FSED ARF+ +++S + Y HS Sbjct: 209 PFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERIFSEDRARFYGAEIVSALDYLHSE 268 Query: 184 MQVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLH-SQPKSTVGTPAYIAPEVLLKKE 360 V +RDLKLEN +LD +KI DFG K + + K+ GTP Y+APEVL + Sbjct: 269 KNVVYRDLKLENLMLDKD--GHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLEDND 326 Query: 361 YDGKIADVWSRGVTLYVML 417 Y G+ D W GV +Y M+ Sbjct: 327 Y-GRAVDWWGLGVVMYEMM 344
>KS6A5_CHICK (Q5F3L1) Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1)| Length = 789 Score = 98.2 bits (243), Expect = 7e-21 Identities = 59/139 (42%), Positives = 78/139 (56%), Gaps = 2/139 (1%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PN+++ EV H +VME GGEL ERI FSE EA ++L+S VS+ H + Sbjct: 469 PNVVKLHEVYHDQLHTFLVMELLKGGELLERIQKKQHFSETEASHIMRRLVSAVSHMHDV 528 Query: 187 QVCHRDLKLENTLL-DGSTAPRLKICDFGYSKSSVLHSQP-KSTVGTPAYIAPEVLLKKE 360 V HRDLK EN L D + +KI DFG+++ +QP K+ T Y APE+ Sbjct: 529 GVVHRDLKPENLLFTDETDNSEIKIIDFGFARLKPPDNQPLKTPCFTLHYAAPELFNHNG 588 Query: 361 YDGKIADVWSRGVTLYVML 417 YD + D+WS GV LY ML Sbjct: 589 YD-ESCDLWSLGVILYTML 606 Score = 79.3 bits (194), Expect = 3e-15 Identities = 44/140 (31%), Positives = 75/140 (53%), Gaps = 3/140 (2%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P ++ T T L ++++Y +GGELF + RFSE+E + + +++ + + H + Sbjct: 102 PFLVTLHYAFQTDTKLHLILDYINGGELFTHLSQRERFSENEVQIYIGEIVLALEHLHKL 161 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPK--STVGTPAYIAPEVLLKKE 360 + +RD+KLEN LLD + + DFG SK + + S GT Y+AP+++ + Sbjct: 162 GIIYRDIKLENILLDSD--GHVVLTDFGLSKEFLTDENERAYSFCGTIEYMAPDIVRGGD 219 Query: 361 Y-DGKIADVWSRGVTLYVML 417 K D WS GV +Y +L Sbjct: 220 TGHDKAVDWWSVGVLMYELL 239
>KAPB2_BOVIN (P24256) cAMP-dependent protein kinase, beta-2-catalytic subunit| (EC 2.7.11.11) (PKA C-beta-2) Length = 397 Score = 98.2 bits (243), Expect = 7e-21 Identities = 52/136 (38%), Positives = 81/136 (59%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P ++R + ++L +VMEY GGE+F + GRFSE ARF+ Q++ Y HS+ Sbjct: 148 PFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSL 207 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 + +RDLK EN L+D +++ DFG++K + + + GTP Y+APE++L K Y+ Sbjct: 208 DLIYRDLKPENLLIDHQ--GYIQVTDFGFAKR--VKGRTWTLCGTPEYLAPEIILSKGYN 263 Query: 367 GKIADVWSRGVTLYVM 414 K D W+ GV +Y M Sbjct: 264 -KAVDWWALGVLIYEM 278
>KAPCB_HUMAN (P22694) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 98.2 bits (243), Expect = 7e-21 Identities = 52/136 (38%), Positives = 81/136 (59%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P ++R + ++L +VMEY GGE+F + GRFSE ARF+ Q++ Y HS+ Sbjct: 101 PFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSL 160 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 + +RDLK EN L+D +++ DFG++K + + + GTP Y+APE++L K Y+ Sbjct: 161 DLIYRDLKPENLLIDHQ--GYIQVTDFGFAKR--VKGRTWTLCGTPEYLAPEIILSKGYN 216 Query: 367 GKIADVWSRGVTLYVM 414 K D W+ GV +Y M Sbjct: 217 -KAVDWWALGVLIYEM 231
>KAPB1_BOVIN (P05131) cAMP-dependent protein kinase, beta-1-catalytic subunit| (EC 2.7.11.11) (PKA C-beta-1) Length = 350 Score = 98.2 bits (243), Expect = 7e-21 Identities = 52/136 (38%), Positives = 81/136 (59%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P ++R + ++L +VMEY GGE+F + GRFSE ARF+ Q++ Y HS+ Sbjct: 101 PFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSL 160 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 + +RDLK EN L+D +++ DFG++K + + + GTP Y+APE++L K Y+ Sbjct: 161 DLIYRDLKPENLLIDHQ--GYIQVTDFGFAKR--VKGRTWTLCGTPEYLAPEIILSKGYN 216 Query: 367 GKIADVWSRGVTLYVM 414 K D W+ GV +Y M Sbjct: 217 -KAVDWWALGVLIYEM 231
>KPCG_RAT (P63319) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| Length = 697 Score = 97.8 bits (242), Expect = 9e-21 Identities = 55/139 (39%), Positives = 77/139 (55%), Gaps = 1/139 (0%) Frame = +1 Query: 4 PPNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHS 183 P + + TP L VMEY +GG+L I G+F E A F+ ++ G+ + H+ Sbjct: 414 PHFLTQLHSTFQTPDRLYFVMEYVTGGDLMYHIQQLGKFKEPHAAFYAAEIAIGLFFLHN 473 Query: 184 MQVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVL-HSQPKSTVGTPAYIAPEVLLKKE 360 + +RDLKL+N +LD +KI DFG K +V S ++ GTP YIAPE++ + Sbjct: 474 QGIIYRDLKLDNVMLDAE--GHIKITDFGMCKENVFPGSTTRTFCGTPDYIAPEIIAYQP 531 Query: 361 YDGKIADVWSRGVTLYVML 417 Y GK D WS GV LY ML Sbjct: 532 Y-GKSVDWWSFGVLLYEML 549
>KPCG_MOUSE (P63318) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| Length = 697 Score = 97.8 bits (242), Expect = 9e-21 Identities = 55/139 (39%), Positives = 77/139 (55%), Gaps = 1/139 (0%) Frame = +1 Query: 4 PPNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHS 183 P + + TP L VMEY +GG+L I G+F E A F+ ++ G+ + H+ Sbjct: 414 PHFLTQLHSTFQTPDRLYFVMEYVTGGDLMYHIQQLGKFKEPHAAFYAAEIAIGLFFLHN 473 Query: 184 MQVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVL-HSQPKSTVGTPAYIAPEVLLKKE 360 + +RDLKL+N +LD +KI DFG K +V S ++ GTP YIAPE++ + Sbjct: 474 QGIIYRDLKLDNVMLDAE--GHIKITDFGMCKENVFPGSTTRTFCGTPDYIAPEIIAYQP 531 Query: 361 YDGKIADVWSRGVTLYVML 417 Y GK D WS GV LY ML Sbjct: 532 Y-GKSVDWWSFGVLLYEML 549
>AKT1_CAEEL (Q17941) Serine/threonine-protein kinase akt-1 (EC 2.7.11.1)| (Protein kinase B akt-1) (PKB akt-1) Length = 541 Score = 97.8 bits (242), Expect = 9e-21 Identities = 52/124 (41%), Positives = 72/124 (58%), Gaps = 1/124 (0%) Frame = +1 Query: 49 HLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSMQVCHRDLKLENTLL 228 +L VM++A+GGELF + G FSE ARF+ +++ + Y H + +RD+KLEN LL Sbjct: 265 YLCFVMQFANGGELFTHVRKCGTFSEPRARFYGAEIVLALGYLHRCDIVYRDMKLENLLL 324 Query: 229 DGSTAPRLKICDFGYSKSSVLHSQPKST-VGTPAYIAPEVLLKKEYDGKIADVWSRGVTL 405 D +KI DFG K + ST GTP Y+APEVL +Y G+ D W GV + Sbjct: 325 DKD--GHIKIADFGLCKEEISFGDKTSTFCGTPEYLAPEVLDDHDY-GRCVDWWGVGVVM 381 Query: 406 YVML 417 Y M+ Sbjct: 382 YEMM 385
>KPCG_BOVIN (P05128) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| (Fragment) Length = 682 Score = 97.8 bits (242), Expect = 9e-21 Identities = 55/139 (39%), Positives = 77/139 (55%), Gaps = 1/139 (0%) Frame = +1 Query: 4 PPNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHS 183 P + + TP L VMEY +GG+L I G+F E A F+ ++ G+ + H+ Sbjct: 399 PHFLTQLHSTFQTPDRLYFVMEYVTGGDLMYHIQQLGKFKEPHAAFYAAEIAIGLFFLHN 458 Query: 184 MQVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVL-HSQPKSTVGTPAYIAPEVLLKKE 360 + +RDLKL+N +LD +KI DFG K +V S ++ GTP YIAPE++ + Sbjct: 459 QGIIYRDLKLDNVMLDAE--GHIKITDFGMCKENVFPGSTTRTFCGTPDYIAPEIIAYQP 516 Query: 361 YDGKIADVWSRGVTLYVML 417 Y GK D WS GV LY ML Sbjct: 517 Y-GKSVDWWSFGVLLYEML 534
>SGK2_MOUSE (Q9QZS5) Serine/threonine-protein kinase Sgk2 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 2) Length = 367 Score = 97.4 bits (241), Expect = 1e-20 Identities = 56/138 (40%), Positives = 76/138 (55%), Gaps = 1/138 (0%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P ++ + TP L V++Y +GGELF + RF E ARF+ ++ S + Y HS+ Sbjct: 94 PFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYTAEVASAIGYLHSL 153 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKST-VGTPAYIAPEVLLKKEY 363 + +RDLK EN LLD + + DFG K V + ST GTP Y+APEVL K+ Y Sbjct: 154 NIIYRDLKPENILLD--CQGHVVLTDFGLCKECVEPEETTSTFCGTPEYLAPEVLRKEPY 211 Query: 364 DGKIADVWSRGVTLYVML 417 D + D W G LY ML Sbjct: 212 D-RAVDWWCLGAVLYEML 228
>SGK2_RAT (Q8R4U9) Serine/threonine-protein kinase Sgk2 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 2) (Fragment) Length = 302 Score = 97.4 bits (241), Expect = 1e-20 Identities = 56/138 (40%), Positives = 76/138 (55%), Gaps = 1/138 (0%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P ++ + TP L V++Y +GGELF + RF E ARF+ ++ S + Y HS+ Sbjct: 77 PFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQREHRFLEPRARFYTAEVASAIGYLHSL 136 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKST-VGTPAYIAPEVLLKKEY 363 + +RDLK EN LLD + + DFG K V + ST GTP Y+APEVL K+ Y Sbjct: 137 NIIYRDLKPENILLD--CQGHVVLTDFGLCKECVEPEETTSTFCGTPEYLAPEVLRKEPY 194 Query: 364 DGKIADVWSRGVTLYVML 417 D + D W G LY ML Sbjct: 195 D-RAVDWWCLGAVLYEML 211
>CDPK3_PLAYO (Q7RAV5) Calcium-dependent protein kinase 3 (EC 2.7.11.1)| Length = 538 Score = 97.4 bits (241), Expect = 1e-20 Identities = 55/139 (39%), Positives = 81/139 (58%), Gaps = 2/139 (1%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PN+I+ E + ++M+ +GGELF++I G F E A F +Q+ S ++Y H Sbjct: 167 PNVIKLLETFEDEEQIYLIMDLCTGGELFDKIIKKGSFVEMYASFIMKQIFSVLNYLHIR 226 Query: 187 QVCHRDLKLENTLL-DGSTAPRLKICDFGYSK-SSVLHSQPKSTVGTPAYIAPEVLLKKE 360 +CHRD+K EN L D ST +KI DFG + + + + K+ GTP Y+AP+VL Sbjct: 227 NICHRDIKPENFLFYDKSTESLIKIIDFGLAAYFNDIDYEMKTKAGTPYYVAPQVLTGC- 285 Query: 361 YDGKIADVWSRGVTLYVML 417 YD K D+WS GV Y++L Sbjct: 286 YDYK-CDLWSAGVLFYIIL 303
>KAPC_CAEEL (P21137) cAMP-dependent protein kinase catalytic subunit (EC| 2.7.11.11) (PKA C) Length = 404 Score = 97.4 bits (241), Expect = 1e-20 Identities = 51/123 (41%), Positives = 78/123 (63%) Frame = +1 Query: 46 THLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSMQVCHRDLKLENTL 225 ++L +V+E+ SGGE+F + GRFSE +RF+ Q++ Y HS+ + +RDLK EN L Sbjct: 152 SNLYMVLEFISGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKPENLL 211 Query: 226 LDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYDGKIADVWSRGVTL 405 +D + LKI DFG++K + + + GTP Y+APE++L K Y+ K D W+ GV + Sbjct: 212 ID--STGYLKITDFGFAKR--VKGRTWTLCGTPEYLAPEIILSKGYN-KAVDWWALGVLI 266 Query: 406 YVM 414 Y M Sbjct: 267 YEM 269
>KAPCB_RAT (P68182) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 97.4 bits (241), Expect = 1e-20 Identities = 52/136 (38%), Positives = 81/136 (59%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P ++R + ++L +VMEY GGE+F + GRFSE ARF+ Q++ Y HS+ Sbjct: 101 PFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSL 160 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 + +RDLK EN L+D +++ DFG++K + + + GTP Y+APE++L K Y+ Sbjct: 161 DLIYRDLKPENLLIDHQ--GYIQVTDFGFAKR--VKGRTWTLCGTPEYLAPEIILSKGYN 216 Query: 367 GKIADVWSRGVTLYVM 414 K D W+ GV +Y M Sbjct: 217 -KAVDWWALGVLIYEM 231
>KAPCB_MOUSE (P68181) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 97.4 bits (241), Expect = 1e-20 Identities = 52/136 (38%), Positives = 81/136 (59%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P ++R + ++L +VMEY GGE+F + GRFSE ARF+ Q++ Y HS+ Sbjct: 101 PFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSL 160 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 + +RDLK EN L+D +++ DFG++K + + + GTP Y+APE++L K Y+ Sbjct: 161 DLIYRDLKPENLLIDHQ--GYIQVTDFGFAKR--VKGRTWTLCGTPEYLAPEIILSKGYN 216 Query: 367 GKIADVWSRGVTLYVM 414 K D W+ GV +Y M Sbjct: 217 -KAVDWWALGVLIYEM 231
>KAPCB_CRIGR (P68180) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 97.4 bits (241), Expect = 1e-20 Identities = 52/136 (38%), Positives = 81/136 (59%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P ++R + ++L +VMEY GGE+F + GRFSE ARF+ Q++ Y HS+ Sbjct: 101 PFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSL 160 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 + +RDLK EN L+D +++ DFG++K + + + GTP Y+APE++L K Y+ Sbjct: 161 DLIYRDLKPENLLIDHQ--GYIQVTDFGFAKR--VKGRTWTLCGTPEYLAPEIILSKGYN 216 Query: 367 GKIADVWSRGVTLYVM 414 K D W+ GV +Y M Sbjct: 217 -KAVDWWALGVLIYEM 231
>KIN1_SCHPO (P22987) Protein kinase kin1 (EC 2.7.11.1)| Length = 891 Score = 97.1 bits (240), Expect = 2e-20 Identities = 52/137 (37%), Positives = 80/137 (58%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P I ++V +T +H +V E+ GG++ + I + G+ E +AR F +Q+ S +SY H Sbjct: 201 PYICEARDVYITNSHYYMVFEFVDGGQMLDYIISHGKLKEKQARKFVRQIGSALSYLHQN 260 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 V HRDLK+EN L+ S +KI DFG S S+ ++ G+ + APE+L + Y Sbjct: 261 SVVHRDLKIENILI--SKTGDIKIIDFGLSNLYRRQSRLRTFCGSLYFAAPELLNAQPYI 318 Query: 367 GKIADVWSRGVTLYVML 417 G DVWS G+ LYV++ Sbjct: 319 GPEVDVWSFGIVLYVLV 335
>SGK2_HUMAN (Q9HBY8) Serine/threonine-protein kinase Sgk2 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 2) Length = 427 Score = 97.1 bits (240), Expect = 2e-20 Identities = 56/138 (40%), Positives = 75/138 (54%), Gaps = 1/138 (0%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P ++ + TP L V++Y +GGELF + RF E ARF+ ++ S + Y HS+ Sbjct: 154 PFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAIGYLHSL 213 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKST-VGTPAYIAPEVLLKKEY 363 + +RDLK EN LLD + + DFG K V ST GTP Y+APEVL K+ Y Sbjct: 214 NIIYRDLKPENILLD--CQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLRKEPY 271 Query: 364 DGKIADVWSRGVTLYVML 417 D + D W G LY ML Sbjct: 272 D-RAVDWWCLGAVLYEML 288
>KPCG_RABIT (P10829) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| (PKC-delta) Length = 697 Score = 97.1 bits (240), Expect = 2e-20 Identities = 55/139 (39%), Positives = 75/139 (53%), Gaps = 1/139 (0%) Frame = +1 Query: 4 PPNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHS 183 P + + TP L VMEY +GG+L I G+F E A F+ ++ G+ + H+ Sbjct: 414 PHFLTQLHSTFQTPDRLYFVMEYVTGGDLMYHIQQLGKFKEPHAAFYAAEIAIGLFFLHN 473 Query: 184 MQVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKST-VGTPAYIAPEVLLKKE 360 + +RDLKL+N +LD +KI DFG K +V T GTP YIAPE++ + Sbjct: 474 QGIIYRDLKLDNVMLDAE--GHIKITDFGMCKENVFPGTTTRTFCGTPDYIAPEIIAYQP 531 Query: 361 YDGKIADVWSRGVTLYVML 417 Y GK D WS GV LY ML Sbjct: 532 Y-GKSVDWWSFGVLLYEML 549
>KPCG_HUMAN (P05129) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| Length = 697 Score = 97.1 bits (240), Expect = 2e-20 Identities = 55/139 (39%), Positives = 75/139 (53%), Gaps = 1/139 (0%) Frame = +1 Query: 4 PPNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHS 183 P + + TP L VMEY +GG+L I G+F E A F+ ++ G+ + H+ Sbjct: 414 PHFLTQLHSTFQTPDRLYFVMEYVTGGDLMYHIQQLGKFKEPHAAFYAAEIAIGLFFLHN 473 Query: 184 MQVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKST-VGTPAYIAPEVLLKKE 360 + +RDLKL+N +LD +KI DFG K +V T GTP YIAPE++ + Sbjct: 474 QGIIYRDLKLDNVMLDAE--GHIKITDFGMCKENVFPGTTTRTFCGTPDYIAPEIIAYQP 531 Query: 361 YDGKIADVWSRGVTLYVML 417 Y GK D WS GV LY ML Sbjct: 532 Y-GKSVDWWSFGVLLYEML 549
>DCAK1_MOUSE (Q9JLM8) Serine/threonine-protein kinase DCAMKL1 (EC 2.7.11.1)| (Doublecortin-like and CAM kinase-like 1) Length = 756 Score = 97.1 bits (240), Expect = 2e-20 Identities = 52/141 (36%), Positives = 83/141 (58%), Gaps = 4/141 (2%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PNI+ E + PT L +VME GG+LF+ I + +++E +A L S + Y HS+ Sbjct: 462 PNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTSKYTERDASGMLYNLASAIKYLHSL 521 Query: 187 QVCHRDLKLENTLL----DGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLK 354 + HRD+K EN L+ DGS + LK+ DFG ++++ + GTP Y+APE++ + Sbjct: 522 NIVHRDIKPENLLVYEHQDGSKS--LKLGDFGL--ATIVDGPLYTVCGTPTYVAPEIIAE 577 Query: 355 KEYDGKIADVWSRGVTLYVML 417 Y K+ D+W+ GV Y++L Sbjct: 578 TGYGLKV-DIWAAGVITYILL 597
>DCAK1_HUMAN (O15075) Serine/threonine-protein kinase DCAMKL1 (EC 2.7.11.1)| (Doublecortin-like and CAM kinase-like 1) Length = 740 Score = 97.1 bits (240), Expect = 2e-20 Identities = 52/141 (36%), Positives = 83/141 (58%), Gaps = 4/141 (2%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PNI+ E + PT L +VME GG+LF+ I + +++E +A L S + Y HS+ Sbjct: 446 PNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSL 505 Query: 187 QVCHRDLKLENTLL----DGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLK 354 + HRD+K EN L+ DGS + LK+ DFG ++++ + GTP Y+APE++ + Sbjct: 506 NIVHRDIKPENLLVYEHQDGSKS--LKLGDFGL--ATIVDGPLYTVCGTPTYVAPEIIAE 561 Query: 355 KEYDGKIADVWSRGVTLYVML 417 Y K+ D+W+ GV Y++L Sbjct: 562 TGYGLKV-DIWAAGVITYILL 581
>KAPCB_PIG (P05383) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 97.1 bits (240), Expect = 2e-20 Identities = 52/136 (38%), Positives = 81/136 (59%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P ++R + ++L +VMEY GGE+F + GRFSE ARF+ Q++ Y HS+ Sbjct: 101 PFLVRLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSL 160 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 + +RDLK EN L+D +++ DFG++K + + + GTP Y+APE++L K Y+ Sbjct: 161 DLIYRDLKPENLLIDHQ--GYIQVTDFGFAKR--VKGRTWTLCGTPEYLAPEIILSKGYN 216 Query: 367 GKIADVWSRGVTLYVM 414 K D W+ GV +Y M Sbjct: 217 -KAVDWWALGVLIYEM 231
>DCAK1_RAT (O08875) Serine/threonine-protein kinase DCAMKL1 (EC 2.7.11.1)| (Doublecortin-like and CAM kinase-like 1) (Calcium/calmodulin-dependent protein kinase type I-like CPG16) Length = 433 Score = 97.1 bits (240), Expect = 2e-20 Identities = 52/141 (36%), Positives = 83/141 (58%), Gaps = 4/141 (2%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PNI+ E + PT L +VME GG+LF+ I + +++E +A L S + Y HS+ Sbjct: 139 PNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTSKYTERDASGMLYNLASAIKYLHSL 198 Query: 187 QVCHRDLKLENTLL----DGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLK 354 + HRD+K EN L+ DGS + LK+ DFG ++++ + GTP Y+APE++ + Sbjct: 199 NIVHRDIKPENLLVYEHQDGSKS--LKLGDFGL--ATIVDGPLYTVCGTPTYVAPEIIAE 254 Query: 355 KEYDGKIADVWSRGVTLYVML 417 Y K+ D+W+ GV Y++L Sbjct: 255 TGYGLKV-DIWAAGVITYILL 274
>DAPK2_MOUSE (Q8VDF3) Death-associated protein kinase 2 (EC 2.7.11.1) (DAP| kinase 2) (DAP-kinase-related protein 1) (DRP-1) Length = 370 Score = 96.7 bits (239), Expect = 2e-20 Identities = 53/139 (38%), Positives = 80/139 (57%), Gaps = 2/139 (1%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PNII +V T + +++E SGGELF+ + SE+EA F +Q+L GV+Y H+ Sbjct: 84 PNIITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEATSFIKQILDGVNYLHTK 143 Query: 187 QVCHRDLKLENTLL--DGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKE 360 ++ H DLK EN +L P +K+ DFG + + K+ GTP ++APE+ + E Sbjct: 144 KIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIEDGVEFKNIFGTPEFVAPEI-VNYE 202 Query: 361 YDGKIADVWSRGVTLYVML 417 G AD+WS GV Y++L Sbjct: 203 PLGLEADMWSIGVITYILL 221
>KKCC2_RAT (O88831) Calcium/calmodulin-dependent protein kinase kinase 2 (EC| 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-kinase kinase beta) (CaM-KK beta) (CaMKK beta) Length = 587 Score = 96.7 bits (239), Expect = 2e-20 Identities = 61/144 (42%), Positives = 84/144 (58%), Gaps = 10/144 (6%) Frame = +1 Query: 7 PNIIRFKEVILTPT--HLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCH 180 PN+++ EV+ P HL +V E + G + E + SED+ARF+FQ L+ G+ Y H Sbjct: 245 PNVVKLVEVLDDPNEDHLYMVFELVNQGPVME-VPTLKPLSEDQARFYFQDLIKGIEYLH 303 Query: 181 SMQVCHRDLKLENTLL--DGSTAPRLKICDFGYSK----SSVLHSQPKSTVGTPAYIAPE 342 ++ HRD+K N L+ DG +KI DFG S S L S +TVGTPA++APE Sbjct: 304 YQKIIHRDIKPSNLLVGEDG----HIKIADFGVSNEFKGSDALLS---NTVGTPAFMAPE 356 Query: 343 VL--LKKEYDGKIADVWSRGVTLY 408 L +K + GK DVW+ GVTLY Sbjct: 357 SLSETRKIFSGKALDVWAMGVTLY 380
>KKCC2_MOUSE (Q8C078) Calcium/calmodulin-dependent protein kinase kinase 2 (EC| 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-kinase kinase beta) (CaM-KK beta) (CaMKK beta) Length = 588 Score = 96.7 bits (239), Expect = 2e-20 Identities = 61/144 (42%), Positives = 84/144 (58%), Gaps = 10/144 (6%) Frame = +1 Query: 7 PNIIRFKEVILTPT--HLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCH 180 PN+++ EV+ P HL +V E + G + E + SED+ARF+FQ L+ G+ Y H Sbjct: 246 PNVVKLVEVLDDPNEDHLYMVFELVNQGPVME-VPTLKPLSEDQARFYFQDLIKGIEYLH 304 Query: 181 SMQVCHRDLKLENTLL--DGSTAPRLKICDFGYSK----SSVLHSQPKSTVGTPAYIAPE 342 ++ HRD+K N L+ DG +KI DFG S S L S +TVGTPA++APE Sbjct: 305 YQKIIHRDIKPSNLLVGEDG----HIKIADFGVSNEFKGSDALLS---NTVGTPAFMAPE 357 Query: 343 VL--LKKEYDGKIADVWSRGVTLY 408 L +K + GK DVW+ GVTLY Sbjct: 358 SLSETRKIFSGKALDVWAMGVTLY 381
>KKCC2_HUMAN (Q96RR4) Calcium/calmodulin-dependent protein kinase kinase 2 (EC| 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-kinase kinase beta) (CaM-KK beta) (CaMKK beta) Length = 588 Score = 96.7 bits (239), Expect = 2e-20 Identities = 61/144 (42%), Positives = 84/144 (58%), Gaps = 10/144 (6%) Frame = +1 Query: 7 PNIIRFKEVILTPT--HLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCH 180 PN+++ EV+ P HL +V E + G + E + SED+ARF+FQ L+ G+ Y H Sbjct: 246 PNVVKLVEVLDDPNEDHLYMVFELVNQGPVME-VPTLKPLSEDQARFYFQDLIKGIEYLH 304 Query: 181 SMQVCHRDLKLENTLL--DGSTAPRLKICDFGYSK----SSVLHSQPKSTVGTPAYIAPE 342 ++ HRD+K N L+ DG +KI DFG S S L S +TVGTPA++APE Sbjct: 305 YQKIIHRDIKPSNLLVGEDG----HIKIADFGVSNEFKGSDALLS---NTVGTPAFMAPE 357 Query: 343 VL--LKKEYDGKIADVWSRGVTLY 408 L +K + GK DVW+ GVTLY Sbjct: 358 SLSETRKIFSGKALDVWAMGVTLY 381
>KCC1_YEAST (P27466) Calcium/calmodulin-dependent protein kinase I (EC| 2.7.11.17) Length = 446 Score = 96.7 bits (239), Expect = 2e-20 Identities = 57/142 (40%), Positives = 81/142 (57%), Gaps = 5/142 (3%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PNI+ FK+ + I+ + A GGELF+RI G+F+E++A ++LS V Y HS Sbjct: 96 PNIVAFKDWFESKDKFYIITQLAKGGELFDRILKKGKFTEEDAVRILVEILSAVKYMHSQ 155 Query: 187 QVCHRDLKLENTL-LDGSTAPRLKICDFGYSK----SSVLHSQPKSTVGTPAYIAPEVLL 351 + HRDLK EN L +D S L + DFG +K L +P ++G Y+APEVL Sbjct: 156 NIVHRDLKPENLLYIDKSDESPLVVADFGIAKRLKSDEELLYKPAGSLG---YVAPEVLT 212 Query: 352 KKEYDGKIADVWSRGVTLYVML 417 + + GK D+WS GV Y +L Sbjct: 213 QDGH-GKPCDIWSIGVITYTLL 233
>KAPCA_MOUSE (P05132) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 96.7 bits (239), Expect = 2e-20 Identities = 51/136 (37%), Positives = 82/136 (60%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P +++ + ++L +VMEY +GGE+F + GRFSE ARF+ Q++ Y HS+ Sbjct: 101 PFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSL 160 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 + +RDLK EN L+D +++ DFG++K + + + GTP Y+APE++L K Y+ Sbjct: 161 DLIYRDLKPENLLID--QQGYIQVTDFGFAKR--VKGRTWTLCGTPEYLAPEIILSKGYN 216 Query: 367 GKIADVWSRGVTLYVM 414 K D W+ GV +Y M Sbjct: 217 -KAVDWWALGVLIYEM 231
>KCC2A_RAT (P11275) Calcium/calmodulin-dependent protein kinase type II alpha| chain (EC 2.7.11.17) (CaM-kinase II alpha chain) (CaM kinase II alpha subunit) (CaMK-II alpha subunit) Length = 478 Score = 96.3 bits (238), Expect = 3e-20 Identities = 57/139 (41%), Positives = 76/139 (54%), Gaps = 2/139 (1%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PNI+R + I H ++ + +GGELFE I +SE +A QQ+L V +CH M Sbjct: 70 PNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQM 129 Query: 187 QVCHRDLKLENTLLDGS-TAPRLKICDFGYSKSSVLHSQP-KSTVGTPAYIAPEVLLKKE 360 V HRDLK EN LL +K+ DFG + Q GTP Y++PEVL K Sbjct: 130 GVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKDP 189 Query: 361 YDGKIADVWSRGVTLYVML 417 Y GK D+W+ GV LY++L Sbjct: 190 Y-GKPVDLWACGVILYILL 207
>KCC2A_PONPY (Q5RCC4) Calcium/calmodulin-dependent protein kinase type II alpha| chain (EC 2.7.11.17) (CaM-kinase II alpha chain) (CaM kinase II alpha subunit) (CaMK-II alpha subunit) Length = 478 Score = 96.3 bits (238), Expect = 3e-20 Identities = 57/139 (41%), Positives = 76/139 (54%), Gaps = 2/139 (1%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PNI+R + I H ++ + +GGELFE I +SE +A QQ+L V +CH M Sbjct: 70 PNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQM 129 Query: 187 QVCHRDLKLENTLLDGS-TAPRLKICDFGYSKSSVLHSQP-KSTVGTPAYIAPEVLLKKE 360 V HRDLK EN LL +K+ DFG + Q GTP Y++PEVL K Sbjct: 130 GVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKDP 189 Query: 361 YDGKIADVWSRGVTLYVML 417 Y GK D+W+ GV LY++L Sbjct: 190 Y-GKPVDLWACGVILYILL 207
>KCC2A_MOUSE (P11798) Calcium/calmodulin-dependent protein kinase type II alpha| chain (EC 2.7.11.17) (CaM-kinase II alpha chain) (CaM kinase II alpha subunit) (CaMK-II alpha subunit) Length = 478 Score = 96.3 bits (238), Expect = 3e-20 Identities = 58/140 (41%), Positives = 78/140 (55%), Gaps = 3/140 (2%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PNI+R + I H ++ + +GGELFE I +SE +A QQ+L V +CH M Sbjct: 70 PNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQM 129 Query: 187 QVCHRDLKLENTLLDGS-TAPRLKICDFGYSKSSVLHSQPK--STVGTPAYIAPEVLLKK 357 V HRDLK EN LL +K+ DFG + V Q + GTP Y++PEVL K Sbjct: 130 GVVHRDLKPENLLLASKLKGAAVKLADFGLA-IEVEGEQQRWFGFAGTPGYLSPEVLRKD 188 Query: 358 EYDGKIADVWSRGVTLYVML 417 Y GK D+W+ GV LY++L Sbjct: 189 PY-GKPVDLWACGVILYILL 207
>KCC2A_HUMAN (Q9UQM7) Calcium/calmodulin-dependent protein kinase type II alpha| chain (EC 2.7.11.17) (CaM-kinase II alpha chain) (CaM kinase II alpha subunit) (CaMK-II alpha subunit) Length = 478 Score = 96.3 bits (238), Expect = 3e-20 Identities = 57/139 (41%), Positives = 76/139 (54%), Gaps = 2/139 (1%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PNI+R + I H ++ + +GGELFE I +SE +A QQ+L V +CH M Sbjct: 70 PNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQM 129 Query: 187 QVCHRDLKLENTLLDGS-TAPRLKICDFGYSKSSVLHSQP-KSTVGTPAYIAPEVLLKKE 360 V HRDLK EN LL +K+ DFG + Q GTP Y++PEVL K Sbjct: 130 GVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKDP 189 Query: 361 YDGKIADVWSRGVTLYVML 417 Y GK D+W+ GV LY++L Sbjct: 190 Y-GKPVDLWACGVILYILL 207
>DUN1_YEAST (P39009) DNA damage response protein kinase DUN1 (EC 2.7.11.1)| Length = 513 Score = 96.3 bits (238), Expect = 3e-20 Identities = 58/159 (36%), Positives = 82/159 (51%), Gaps = 22/159 (13%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLA-----IVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVS 171 PNI+ + + P + +V+E GELFERI +DE++ F+QLL+G+ Sbjct: 258 PNIVNLLDSFVEPISKSQIQKYLVLEKIDDGELFERIVRKTCLRQDESKALFKQLLTGLK 317 Query: 172 YCHSMQVCHRDLKLENTLL-----------------DGSTAPRLKICDFGYSKSSVLHSQ 300 Y H + HRD+K EN LL + ++KI DFG +K + Sbjct: 318 YLHEQNIIHRDIKPENILLNITRRENPSQVQLGPWDEDEIDIQVKIADFGLAKFTGEMQF 377 Query: 301 PKSTVGTPAYIAPEVLLKKEYDGKIADVWSRGVTLYVML 417 + GTP+Y+APEVL KK Y K+ D+WS GV LYV L Sbjct: 378 TNTLCGTPSYVAPEVLTKKGYTSKV-DLWSAGVILYVCL 415
>KPSH2_HUMAN (Q96QS6) Serine/threonine-protein kinase H2 (EC 2.7.11.1) (PSK-H2)| Length = 385 Score = 96.3 bits (238), Expect = 3e-20 Identities = 55/138 (39%), Positives = 79/138 (57%), Gaps = 3/138 (2%) Frame = +1 Query: 13 IIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSMQV 192 I++ E+ T + +VME A+GGELF+R+ G F+E +A Q + G+ Y H++Q+ Sbjct: 120 IVQLMEIFETEDQVYMVMELATGGELFDRLIAQGSFTERDAVRILQMVADGIRYLHALQI 179 Query: 193 CHRDLKLENTL-LDGSTAPRLKICDFG--YSKSSVLHSQPKSTVGTPAYIAPEVLLKKEY 363 HR+LK EN L ++ I DFG YS K+ GTP YIAPEVLL+K Y Sbjct: 180 THRNLKPENLLYYHPGEESKILITDFGLAYSGKKSGDWTMKTLCGTPEYIAPEVLLRKPY 239 Query: 364 DGKIADVWSRGVTLYVML 417 + D+W+ GV Y +L Sbjct: 240 TSAV-DMWALGVITYALL 256
>LOK_DROME (O61267) Ovarian-specific serine/threonine-protein kinase Lok (EC| 2.7.11.1) (Protein loki) (dMNK) Length = 476 Score = 96.3 bits (238), Expect = 3e-20 Identities = 52/140 (37%), Positives = 78/140 (55%), Gaps = 3/140 (2%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P ++R +++ P + +V+E+ GG+L RI + SED ++ +F Q+ V Y H Sbjct: 238 PCVVRMHDIVDKPDSVYMVLEFMRGGDLLNRIISNKLLSEDISKLYFYQMCHAVKYLHDR 297 Query: 187 QVCHRDLKLENTLLD-GSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLK--K 357 + HRDLK +N LL+ LK+ DFG SK S ++ GTP Y+APEVL+ + Sbjct: 298 GITHRDLKPDNVLLETNDEETLLKVSDFGLSKFVQKDSVMRTLCGTPLYVAPEVLITGGR 357 Query: 358 EYDGKIADVWSRGVTLYVML 417 E K D+WS GV L+ L Sbjct: 358 EAYTKKVDIWSLGVVLFTCL 377
>KAPCA_PIG (P36887) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 96.3 bits (238), Expect = 3e-20 Identities = 51/136 (37%), Positives = 81/136 (59%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P +++ + ++L +VMEY GGE+F + GRFSE ARF+ Q++ Y HS+ Sbjct: 101 PFLVKLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSL 160 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 + +RDLK EN L+D +++ DFG++K + + + GTP Y+APE++L K Y+ Sbjct: 161 DLIYRDLKPENLLID--QQGYIQVTDFGFAKR--VKGRTWTLCGTPEYLAPEIILSKGYN 216 Query: 367 GKIADVWSRGVTLYVM 414 K D W+ GV +Y M Sbjct: 217 -KAVDWWALGVLIYEM 231
>CDPK3_ORYSA (P53684) Calcium-dependent protein kinase, isoform 11 (EC 2.7.11.1)| (CDPK 11) Length = 542 Score = 96.3 bits (238), Expect = 3e-20 Identities = 60/137 (43%), Positives = 79/137 (57%), Gaps = 1/137 (0%) Frame = +1 Query: 10 NIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSMQ 189 N++ K+V + IVME +GGELF+RI G +SE +A + ++S V+ CHS+ Sbjct: 139 NVVAIKDVYEDGQAVHIVMELCAGGELFDRIQEKGHYSERKAAELIRIIVSIVAMCHSLG 198 Query: 190 VCHRDLKLEN-TLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 V HRDLK EN LLD +K DFG S VG+P Y+APEVL K+ Sbjct: 199 VMHRDLKPENFLLLDKDDDLSIKAIDFGLSVFFKPGQVFTELVGSPYYVAPEVLHKRY-- 256 Query: 367 GKIADVWSRGVTLYVML 417 G +DVWS GV LYV+L Sbjct: 257 GPESDVWSAGVILYVLL 273
>KCC2A_DROME (Q00168) Calcium/calmodulin-dependent protein kinase type II alpha| chain (EC 2.7.11.17) (CaM-kinase II alpha chain) Length = 530 Score = 96.3 bits (238), Expect = 3e-20 Identities = 56/139 (40%), Positives = 79/139 (56%), Gaps = 2/139 (1%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PNI+R + I + +V + +GGELFE I +SE +A QQ+L V++CH Sbjct: 71 PNIVRLHDSIQEENYHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVNHCHQN 130 Query: 187 QVCHRDLKLENTLL-DGSTAPRLKICDFGYS-KSSVLHSQPKSTVGTPAYIAPEVLLKKE 360 V HRDLK EN LL + +K+ DFG + + H GTP Y++PEVL K+ Sbjct: 131 GVVHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDHQAWFGFAGTPGYLSPEVLKKEP 190 Query: 361 YDGKIADVWSRGVTLYVML 417 Y GK D+W+ GV LY++L Sbjct: 191 Y-GKSVDIWACGVILYILL 208
>KAPCA_SHEEP (Q9MZD9) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 95.9 bits (237), Expect = 3e-20 Identities = 51/136 (37%), Positives = 81/136 (59%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P +++ + ++L +VMEY GGE+F + GRFSE ARF+ Q++ Y HS+ Sbjct: 101 PFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSL 160 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 + +RDLK EN L+D +++ DFG++K + + + GTP Y+APE++L K Y+ Sbjct: 161 DLIYRDLKPENLLID--QQGYIQVTDFGFAKR--VKGRTWTLCGTPEYLAPEIILSKGYN 216 Query: 367 GKIADVWSRGVTLYVM 414 K D W+ GV +Y M Sbjct: 217 -KAVDWWALGVLIYEM 231
>KAPCA_RAT (P27791) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 95.9 bits (237), Expect = 3e-20 Identities = 51/136 (37%), Positives = 81/136 (59%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P +++ + ++L +VMEY GGE+F + GRFSE ARF+ Q++ Y HS+ Sbjct: 101 PFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSL 160 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 + +RDLK EN L+D +++ DFG++K + + + GTP Y+APE++L K Y+ Sbjct: 161 DLIYRDLKPENLLID--QQGYIQVTDFGFAKR--VKGRTWTLCGTPEYLAPEIILSKGYN 216 Query: 367 GKIADVWSRGVTLYVM 414 K D W+ GV +Y M Sbjct: 217 -KAVDWWALGVLIYEM 231
>KAPCA_HUMAN (P17612) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 95.9 bits (237), Expect = 3e-20 Identities = 51/136 (37%), Positives = 81/136 (59%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P +++ + ++L +VMEY GGE+F + GRFSE ARF+ Q++ Y HS+ Sbjct: 101 PFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSL 160 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 + +RDLK EN L+D +++ DFG++K + + + GTP Y+APE++L K Y+ Sbjct: 161 DLIYRDLKPENLLID--QQGYIQVTDFGFAKR--VKGRTWTLCGTPEYLAPEIILSKGYN 216 Query: 367 GKIADVWSRGVTLYVM 414 K D W+ GV +Y M Sbjct: 217 -KAVDWWALGVLIYEM 231
>KAPCA_CRIGR (P25321) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 95.9 bits (237), Expect = 3e-20 Identities = 51/136 (37%), Positives = 81/136 (59%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P +++ + ++L +VMEY GGE+F + GRFSE ARF+ Q++ Y HS+ Sbjct: 101 PFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSL 160 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 + +RDLK EN L+D +++ DFG++K + + + GTP Y+APE++L K Y+ Sbjct: 161 DLIYRDLKPENLLID--QQGYIQVTDFGFAKR--VKGRTWTLCGTPEYLAPEIILSKGYN 216 Query: 367 GKIADVWSRGVTLYVM 414 K D W+ GV +Y M Sbjct: 217 -KAVDWWALGVLIYEM 231
>KAPCA_BOVIN (P00517) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 95.9 bits (237), Expect = 3e-20 Identities = 51/136 (37%), Positives = 81/136 (59%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P +++ + ++L +VMEY GGE+F + GRFSE ARF+ Q++ Y HS+ Sbjct: 101 PFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSL 160 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 + +RDLK EN L+D +++ DFG++K + + + GTP Y+APE++L K Y+ Sbjct: 161 DLIYRDLKPENLLID--QQGYIQVTDFGFAKR--VKGRTWTLCGTPEYLAPEIILSKGYN 216 Query: 367 GKIADVWSRGVTLYVM 414 K D W+ GV +Y M Sbjct: 217 -KAVDWWALGVLIYEM 231
>KAPCA_CANFA (Q8MJ44) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 349 Score = 95.9 bits (237), Expect = 3e-20 Identities = 51/136 (37%), Positives = 81/136 (59%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P +++ + ++L +VMEY GGE+F + GRFSE ARF+ Q++ Y HS+ Sbjct: 100 PFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSL 159 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 + +RDLK EN L+D +++ DFG++K + + + GTP Y+APE++L K Y+ Sbjct: 160 DLIYRDLKPENLLID--QQGYIQVTDFGFAKR--VKGRTWTLCGTPEYLAPEIILSKGYN 215 Query: 367 GKIADVWSRGVTLYVM 414 K D W+ GV +Y M Sbjct: 216 -KAVDWWALGVLIYEM 230
>CDPK_SOYBN (P28583) Calcium-dependent protein kinase SK5 (EC 2.7.11.1) (CDPK)| Length = 508 Score = 95.5 bits (236), Expect = 4e-20 Identities = 58/137 (42%), Positives = 77/137 (56%), Gaps = 1/137 (0%) Frame = +1 Query: 10 NIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSMQ 189 N++R + T + +VME GGELF+RI G +SE +A + ++ V CHS+ Sbjct: 94 NVVRIEGTYEDSTAVHLVMELCEGGELFDRIVQKGHYSERQAARLIKTIVEVVEACHSLG 153 Query: 190 VCHRDLKLENTLLDG-STAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 V HRDLK EN L D +LK DFG S VG+P Y+APEV L+K Y Sbjct: 154 VMHRDLKPENFLFDTIDEDAKLKATDFGLSVFYKPGESFCDVVGSPYYVAPEV-LRKLY- 211 Query: 367 GKIADVWSRGVTLYVML 417 G +DVWS GV LY++L Sbjct: 212 GPESDVWSAGVILYILL 228
>KDC2_DROME (P16912) Protein kinase DC2 (EC 2.7.11.1)| Length = 583 Score = 95.5 bits (236), Expect = 4e-20 Identities = 51/137 (37%), Positives = 82/137 (59%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P +I + ++L ++ +Y GGELF + NAG+F+ + F+ +++S + Y HS+ Sbjct: 332 PFVISLEWSTKDDSNLYMIFDYVCGGELFTYLRNAGKFTSQTSNFYAAEIVSALEYLHSL 391 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 Q+ +RDLK EN L++ LKI DFG++K L + + GTP YIAPE++ K ++ Sbjct: 392 QIVYRDLKPENLLINRD--GHLKITDFGFAKK--LRDRTWTLCGTPEYIAPEIIQSKGHN 447 Query: 367 GKIADVWSRGVTLYVML 417 K D W+ GV +Y ML Sbjct: 448 -KAVDWWALGVLIYEML 463
>AKT2_CAEEL (Q9XTG7) Serine/threonine-protein kinase akt-2 (EC 2.7.11.1)| (Protein kinase B akt-2) (PKB akt-2) Length = 528 Score = 95.5 bits (236), Expect = 4e-20 Identities = 50/124 (40%), Positives = 71/124 (57%), Gaps = 1/124 (0%) Frame = +1 Query: 49 HLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSMQVCHRDLKLENTLL 228 H+ VME+A+GGELF + FSE RF+ +++ + Y H + +RD+KLEN LL Sbjct: 252 HICFVMEFANGGELFTHLQRCKTFSEARTRFYGSEIILALGYLHHRNIVYRDMKLENLLL 311 Query: 229 DGSTAPRLKICDFGYSKSSVLHSQPKST-VGTPAYIAPEVLLKKEYDGKIADVWSRGVTL 405 D +KI DFG K + + ST GTP Y+APEV+ +YD + D W GV + Sbjct: 312 DRD--GHIKITDFGLCKEEIKYGDKTSTFCGTPEYLAPEVIEDIDYDRSV-DWWGVGVVM 368 Query: 406 YVML 417 Y M+ Sbjct: 369 YEMM 372
>CDPK3_PLAF7 (Q9NJU9) Calcium-dependent protein kinase 3 (EC 2.7.11.1) (PfCDPK3)| Length = 562 Score = 95.1 bits (235), Expect = 6e-20 Identities = 55/140 (39%), Positives = 81/140 (57%), Gaps = 3/140 (2%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PN+++ E + +VME +GGELF++I G F E A F +Q+ S ++Y H Sbjct: 173 PNVVKLLETFEDSNQIYLVMELCTGGELFDKIVKKGCFVETFASFIMKQIFSVLNYLHIR 232 Query: 187 QVCHRDLKLENTLL-DGSTAPRLKICDFGYSKSSVLHS--QPKSTVGTPAYIAPEVLLKK 357 +CHRD+K EN L D + +KI DFG + S H+ + K+ GTP Y+AP+V L Sbjct: 233 NICHRDIKPENFLFYDMTPESLIKIIDFGLA-SYFTHNNYEMKTKAGTPYYVAPQV-LTG 290 Query: 358 EYDGKIADVWSRGVTLYVML 417 Y+ K D+WS GV Y++L Sbjct: 291 SYNYK-CDMWSSGVLFYILL 309
>KS6A5_MOUSE (Q8C050) Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1) (Nuclear| mitogen-and stress-activated protein kinase 1) (90 kDa ribosomal protein S6 kinase 5) (RSK-like protein kinase) (RLSK) Length = 863 Score = 95.1 bits (235), Expect = 6e-20 Identities = 56/125 (44%), Positives = 75/125 (60%), Gaps = 2/125 (1%) Frame = +1 Query: 49 HLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSMQVCHRDLKLENTLL 228 H +VME +GGELFERI FSE EA + ++L+S VS+ H + V HRDLK EN L Sbjct: 557 HTFLVMELLNGGELFERIKRKKHFSETEASYIMRKLVSAVSHMHDVGVVHRDLKPENLLF 616 Query: 229 -DGSTAPRLKICDFGYSKSSVLHSQP-KSTVGTPAYIAPEVLLKKEYDGKIADVWSRGVT 402 D + +K+ DFG+++ +QP K+ T Y APE+L YD + D+WS GV Sbjct: 617 TDENDNLEIKVIDFGFARLKPPDNQPLKTPCFTLHYAAPELLTHNGYD-ESCDLWSLGVI 675 Query: 403 LYVML 417 LY ML Sbjct: 676 LYTML 680 Score = 78.6 bits (192), Expect = 6e-15 Identities = 44/140 (31%), Positives = 75/140 (53%), Gaps = 3/140 (2%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P ++ T T L ++++Y +GGELF + RF+E E + + +++ + + H + Sbjct: 111 PFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLALEHLHKL 170 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPK--STVGTPAYIAPEVLLKKE 360 + +RD+KLEN LLD + + + DFG SK V + S GT Y+AP+++ + Sbjct: 171 GIIYRDIKLENILLDSN--GHVVLTDFGLSKEFVADETERAYSFCGTIEYMAPDIVRGGD 228 Query: 361 Y-DGKIADVWSRGVTLYVML 417 K D WS GV +Y +L Sbjct: 229 SGHDKAVDWWSLGVLMYELL 248
>CHK1_CHICK (Q8AYC9) Serine/threonine-protein kinase Chk1 (EC 2.7.11.1)| Length = 476 Score = 95.1 bits (235), Expect = 6e-20 Identities = 57/123 (46%), Positives = 72/123 (58%), Gaps = 3/123 (2%) Frame = +1 Query: 58 IVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSMQVCHRDLKLENTLLDGS 237 + +EY SGGELF+RI E EA+ FFQQL++GV Y HSM + HRDLK EN LLD Sbjct: 82 LFLEYCSGGELFDRIEPDIGMPEPEAQRFFQQLIAGVVYLHSMGITHRDLKPENLLLD-- 139 Query: 238 TAPRLKICDFGYS---KSSVLHSQPKSTVGTPAYIAPEVLLKKEYDGKIADVWSRGVTLY 408 LKI DFG + K + GT Y+APE+L + E+ + DVW+ GV L Sbjct: 140 ERDNLKISDFGLATVFKHNGRERLLNKMCGTLPYVAPELLRRPEFRAEPVDVWACGVVLT 199 Query: 409 VML 417 ML Sbjct: 200 AML 202
>KPK1_ARATH (P42818) Serine/threonine-protein kinase AtPK1/AtPK6 (EC 2.7.11.1)| Length = 465 Score = 95.1 bits (235), Expect = 6e-20 Identities = 53/137 (38%), Positives = 81/137 (59%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P I++ K T L +V+++ +GG LF ++ + G F ED AR + +++S VS+ H Sbjct: 192 PFIVQLKYSFQTKYRLYLVLDFINGGHLFFQLYHQGLFREDLARVYTAEIVSAVSHLHEK 251 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 + HRDLK EN L+D T + + DFG +K +++ S GT Y+APE++ K +D Sbjct: 252 GIMHRDLKPENILMD--TDGHVMLTDFGLAKEFEENTRSNSMCGTTEYMAPEIVRGKGHD 309 Query: 367 GKIADVWSRGVTLYVML 417 K AD WS G+ LY ML Sbjct: 310 -KAADWWSVGILLYEML 325
>KPCA_RAT (P05696) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 94.4 bits (233), Expect = 1e-19 Identities = 53/139 (38%), Positives = 76/139 (54%), Gaps = 1/139 (0%) Frame = +1 Query: 4 PPNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHS 183 PP + + T L VMEY +GG+L I G+F E +A F+ ++ G+ + H Sbjct: 396 PPFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHK 455 Query: 184 MQVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKST-VGTPAYIAPEVLLKKE 360 + +RDLKL+N +LD + +KI DFG K ++ T GTP YIAPE++ + Sbjct: 456 RGIIYRDLKLDNVMLD--SEGHIKIADFGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQP 513 Query: 361 YDGKIADVWSRGVTLYVML 417 Y GK D W+ GV LY ML Sbjct: 514 Y-GKSVDWWAYGVLLYEML 531
>KPCA_RABIT (P10102) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 94.4 bits (233), Expect = 1e-19 Identities = 53/139 (38%), Positives = 76/139 (54%), Gaps = 1/139 (0%) Frame = +1 Query: 4 PPNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHS 183 PP + + T L VMEY +GG+L I G+F E +A F+ ++ G+ + H Sbjct: 396 PPFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHK 455 Query: 184 MQVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKST-VGTPAYIAPEVLLKKE 360 + +RDLKL+N +LD + +KI DFG K ++ T GTP YIAPE++ + Sbjct: 456 RGIIYRDLKLDNVMLD--SEGHIKIADFGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQP 513 Query: 361 YDGKIADVWSRGVTLYVML 417 Y GK D W+ GV LY ML Sbjct: 514 Y-GKSVDWWAYGVLLYEML 531
>KPCA_HUMAN (P17252) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 94.4 bits (233), Expect = 1e-19 Identities = 53/139 (38%), Positives = 76/139 (54%), Gaps = 1/139 (0%) Frame = +1 Query: 4 PPNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHS 183 PP + + T L VMEY +GG+L I G+F E +A F+ ++ G+ + H Sbjct: 396 PPFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHK 455 Query: 184 MQVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKST-VGTPAYIAPEVLLKKE 360 + +RDLKL+N +LD + +KI DFG K ++ T GTP YIAPE++ + Sbjct: 456 RGIIYRDLKLDNVMLD--SEGHIKIADFGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQP 513 Query: 361 YDGKIADVWSRGVTLYVML 417 Y GK D W+ GV LY ML Sbjct: 514 Y-GKSVDWWAYGVLLYEML 531
>KPCA_BOVIN (P04409) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 94.4 bits (233), Expect = 1e-19 Identities = 53/139 (38%), Positives = 76/139 (54%), Gaps = 1/139 (0%) Frame = +1 Query: 4 PPNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHS 183 PP + + T L VMEY +GG+L I G+F E +A F+ ++ G+ + H Sbjct: 396 PPFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHK 455 Query: 184 MQVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKST-VGTPAYIAPEVLLKKE 360 + +RDLKL+N +LD + +KI DFG K ++ T GTP YIAPE++ + Sbjct: 456 RGIIYRDLKLDNVMLD--SEGHIKIADFGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQP 513 Query: 361 YDGKIADVWSRGVTLYVML 417 Y GK D W+ GV LY ML Sbjct: 514 Y-GKSVDWWAYGVLLYEML 531
>KCC1_EMENI (Q00771) Calcium/calmodulin-dependent protein kinase (EC 2.7.11.17)| (CMPK) Length = 414 Score = 94.4 bits (233), Expect = 1e-19 Identities = 57/143 (39%), Positives = 81/143 (56%), Gaps = 6/143 (4%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P+I+ F + + IV + A+GGELF+RIC G+F+E +A +Q+L V+Y H Sbjct: 77 PHIVHFVDWFESKDKFYIVTQLATGGELFDRICEYGKFTEKDASQTIRQVLDAVNYLHQR 136 Query: 187 QVCHRDLKLENTL-LDGSTAPRLKICDFGYSK-----SSVLHSQPKSTVGTPAYIAPEVL 348 + HRDLK EN L L +L + DFG +K + VL S G+ Y APEV+ Sbjct: 137 NIVHRDLKPENLLYLTRDLDSQLVLADFGIAKMLDNPAEVL----TSMAGSFGYAAPEVM 192 Query: 349 LKKEYDGKIADVWSRGVTLYVML 417 LK+ + GK D+WS GV Y +L Sbjct: 193 LKQGH-GKAVDIWSLGVITYTLL 214
>SCK1_SCHPO (P50530) Serine/threonine-protein kinase sck1 (EC 2.7.11.1)| Length = 696 Score = 94.4 bits (233), Expect = 1e-19 Identities = 52/137 (37%), Positives = 79/137 (57%), Gaps = 1/137 (0%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P I+ K T + L ++ +Y SGGELF + + GRF E A+F+ +L+ + + H Sbjct: 363 PFIVGLKFSFQTASDLYLITDYMSGGELFWHLQHEGRFPEQRAKFYIAELVLALEHLHKH 422 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKST-VGTPAYIAPEVLLKKEY 363 + +RDLK EN LLD + +CDFG SK+++ + +T GT Y+APEVLL+ + Sbjct: 423 DIIYRDLKPENILLDAD--GHIALCDFGLSKANLSANATTNTFCGTTEYLAPEVLLEDKG 480 Query: 364 DGKIADVWSRGVTLYVM 414 K D WS GV ++ M Sbjct: 481 YTKQVDFWSLGVLVFEM 497
>SGK1_HUMAN (O00141) Serine/threonine-protein kinase Sgk1 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 1) Length = 431 Score = 94.4 bits (233), Expect = 1e-19 Identities = 53/127 (41%), Positives = 73/127 (57%), Gaps = 1/127 (0%) Frame = +1 Query: 40 TPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSMQVCHRDLKLEN 219 T L V++Y +GGELF + F E ARF+ ++ S + Y HS+ + +RDLK EN Sbjct: 168 TADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNIVYRDLKPEN 227 Query: 220 TLLDGSTAPRLKICDFGYSKSSVLHSQPKST-VGTPAYIAPEVLLKKEYDGKIADVWSRG 396 LLD + + + DFG K ++ H+ ST GTP Y+APEVL K+ YD + D W G Sbjct: 228 ILLD--SQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQPYD-RTVDWWCLG 284 Query: 397 VTLYVML 417 LY ML Sbjct: 285 AVLYEML 291
>KAPC_DROME (P12370) cAMP-dependent protein kinase catalytic subunit (EC| 2.7.11.11) (PKA C) Length = 352 Score = 94.4 bits (233), Expect = 1e-19 Identities = 49/123 (39%), Positives = 76/123 (61%) Frame = +1 Query: 46 THLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSMQVCHRDLKLENTL 225 ++L +V+EY GGE+F + GRFSE +RF+ Q++ Y H + + +RDLK EN L Sbjct: 116 SNLYMVLEYVPGGEMFSHLRKVGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLL 175 Query: 226 LDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYDGKIADVWSRGVTL 405 +D + LK+ DFG++K + + + GTP Y+APE++L K Y+ K D W+ GV + Sbjct: 176 ID--SQGYLKVTDFGFAKR--VKGRTWTLCGTPEYLAPEIILSKGYN-KAVDWWALGVLV 230 Query: 406 YVM 414 Y M Sbjct: 231 YEM 233
>KCC2_YEAST (P22517) Calcium/calmodulin-dependent protein kinase II (EC| 2.7.11.17) Length = 447 Score = 94.4 bits (233), Expect = 1e-19 Identities = 59/141 (41%), Positives = 79/141 (56%), Gaps = 4/141 (2%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PNI+ FK+ + IV + A+GGELF+RI + G+F+E +A Q+L V Y HS Sbjct: 106 PNIVSFKDWFESKDKFYIVTQLATGGELFDRILSRGKFTEVDAVEIIVQILGAVEYMHSK 165 Query: 187 QVCHRDLKLENTL-LDGSTAPRLKICDFGYSKSSVLHSQPK---STVGTPAYIAPEVLLK 354 V HRDLK EN L +D S L I DFG +K L + G+ Y+APEVL + Sbjct: 166 NVVHRDLKPENVLYVDKSENSPLVIADFGIAKQ--LKGEEDLIYKAAGSLGYVAPEVLTQ 223 Query: 355 KEYDGKIADVWSRGVTLYVML 417 + GK D+WS GV Y +L Sbjct: 224 DGH-GKPCDIWSIGVITYTLL 243
>ULK2_MOUSE (Q9QY01) Serine/threonine-protein kinase ULK2 (EC 2.7.11.1)| (Unc-51-like kinase 2) (Serine/threonine-protein kinase Unc51.2) Length = 1037 Score = 94.4 bits (233), Expect = 1e-19 Identities = 51/143 (35%), Positives = 79/143 (55%), Gaps = 7/143 (4%) Frame = +1 Query: 10 NIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSMQ 189 NI+ +V P + +VMEY +GG+L + + G SED R F Q+ + + HS Sbjct: 67 NIVALYDVQELPNSVFLVMEYCNGGDLADYLQAKGTLSEDTIRVFLHQIAAAMRILHSKG 126 Query: 190 VCHRDLKLENTLL-------DGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVL 348 + HRDLK +N LL + R+KI DFG+++ ++ + G+P Y+APEV+ Sbjct: 127 IIHRDLKPQNILLSYANRRKSNVSGIRIKIADFGFARYLHSNTMAATLCGSPMYMAPEVI 186 Query: 349 LKKEYDGKIADVWSRGVTLYVML 417 + + YD K AD+WS G +Y L Sbjct: 187 MSQHYDAK-ADLWSIGTVIYQCL 208
>KIN2_YEAST (P13186) Serine/threonine-protein kinase KIN2 (EC 2.7.11.1)| Length = 1147 Score = 94.0 bits (232), Expect = 1e-19 Identities = 49/137 (35%), Positives = 75/137 (54%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P+I R E+ H ++ EY SGG+L + I G E AR F + + S + Y H+ Sbjct: 183 PHICRLFEMCTMSNHFYMLFEYVSGGQLLDYIIQHGSLKEHHARKFARGIASALQYLHAN 242 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 + HRDLK+EN ++ S++ +KI DFG S Q + G+ + APE+L + Y Sbjct: 243 NIVHRDLKIENIMI--SSSGEIKIIDFGLSNIFDYRKQLHTFCGSLYFAAPELLKAQPYT 300 Query: 367 GKIADVWSRGVTLYVML 417 G D+WS G+ LYV++ Sbjct: 301 GPEVDIWSFGIVLYVLV 317
>CDPK4_PLAYO (Q7RJG2) Calcium-dependent protein kinase 4 (EC 2.7.11.1)| Length = 527 Score = 94.0 bits (232), Expect = 1e-19 Identities = 57/138 (41%), Positives = 77/138 (55%), Gaps = 2/138 (1%) Frame = +1 Query: 10 NIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSMQ 189 NI++ E + +V + SGGELF+ I + RF E +A +Q+LSG++Y H Sbjct: 128 NIMKLYEFFEDNNYYYLVSDVYSGGELFDEIISRKRFYEVDAARIIKQVLSGITYMHKNN 187 Query: 190 VCHRDLKLENTLLDGSTAPR--LKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEY 363 V HRDLK EN LL+ +KI DFG S + K +GT YIAP+V L Y Sbjct: 188 VVHRDLKPENILLETKNKEDMIIKIIDFGLSTHFEYSKKMKDKIGTAYYIAPDV-LHGTY 246 Query: 364 DGKIADVWSRGVTLYVML 417 D K D+WS GV LY++L Sbjct: 247 DEK-CDIWSCGVILYILL 263
>CDPK4_PLABA (P62345) Calcium-dependent protein kinase 4 (EC 2.7.11.1) (PbCDPK4)| Length = 527 Score = 94.0 bits (232), Expect = 1e-19 Identities = 57/138 (41%), Positives = 77/138 (55%), Gaps = 2/138 (1%) Frame = +1 Query: 10 NIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSMQ 189 NI++ E + +V + SGGELF+ I + RF E +A +Q+LSG++Y H Sbjct: 128 NIMKLYEFFEDNNYYYLVSDVYSGGELFDEIISRKRFYEVDAARIIKQVLSGITYMHKNN 187 Query: 190 VCHRDLKLENTLLDGSTAPR--LKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEY 363 V HRDLK EN LL+ +KI DFG S + K +GT YIAP+V L Y Sbjct: 188 VVHRDLKPENILLETKNKEDMIIKIIDFGLSTHFEYSKKMKDKIGTAYYIAPDV-LHGTY 246 Query: 364 DGKIADVWSRGVTLYVML 417 D K D+WS GV LY++L Sbjct: 247 DEK-CDIWSCGVILYILL 263
>KPCB_MOUSE (P68404) Protein kinase C beta type (EC 2.7.11.13) (PKC-beta)| (PKC-B) Length = 672 Score = 94.0 bits (232), Expect = 1e-19 Identities = 54/139 (38%), Positives = 76/139 (54%), Gaps = 1/139 (0%) Frame = +1 Query: 4 PPNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHS 183 PP + + T L VMEY +GG+L I GRF E A F+ ++ G+ + S Sbjct: 399 PPFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQS 458 Query: 184 MQVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHS-QPKSTVGTPAYIAPEVLLKKE 360 + +RDLKL+N +LD + +KI DFG K ++ K+ GTP YIAPE++ + Sbjct: 459 KGIIYRDLKLDNVMLD--SEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQP 516 Query: 361 YDGKIADVWSRGVTLYVML 417 Y GK D W+ GV LY ML Sbjct: 517 Y-GKSVDWWAFGVLLYEML 534
>KPCB_BOVIN (P05126) Protein kinase C beta type (EC 2.7.11.13) (PKC-beta)| (PKC-B) Length = 672 Score = 94.0 bits (232), Expect = 1e-19 Identities = 54/139 (38%), Positives = 76/139 (54%), Gaps = 1/139 (0%) Frame = +1 Query: 4 PPNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHS 183 PP + + T L VMEY +GG+L I GRF E A F+ ++ G+ + S Sbjct: 399 PPFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQS 458 Query: 184 MQVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHS-QPKSTVGTPAYIAPEVLLKKE 360 + +RDLKL+N +LD + +KI DFG K ++ K+ GTP YIAPE++ + Sbjct: 459 KGIIYRDLKLDNVMLD--SEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQP 516 Query: 361 YDGKIADVWSRGVTLYVML 417 Y GK D W+ GV LY ML Sbjct: 517 Y-GKSVDWWAFGVLLYEML 534
>KPCB_RAT (P68403) Protein kinase C beta type (EC 2.7.11.13) (PKC-beta)| (PKC-B) Length = 670 Score = 94.0 bits (232), Expect = 1e-19 Identities = 54/139 (38%), Positives = 76/139 (54%), Gaps = 1/139 (0%) Frame = +1 Query: 4 PPNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHS 183 PP + + T L VMEY +GG+L I GRF E A F+ ++ G+ + S Sbjct: 399 PPFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQS 458 Query: 184 MQVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHS-QPKSTVGTPAYIAPEVLLKKE 360 + +RDLKL+N +LD + +KI DFG K ++ K+ GTP YIAPE++ + Sbjct: 459 KGIIYRDLKLDNVMLD--SEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQP 516 Query: 361 YDGKIADVWSRGVTLYVML 417 Y GK D W+ GV LY ML Sbjct: 517 Y-GKSVDWWAFGVLLYEML 534
>KPCB_RABIT (P05772) Protein kinase C beta type (EC 2.7.11.13) (PKC-beta)| (PKC-B) Length = 670 Score = 94.0 bits (232), Expect = 1e-19 Identities = 54/139 (38%), Positives = 76/139 (54%), Gaps = 1/139 (0%) Frame = +1 Query: 4 PPNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHS 183 PP + + T L VMEY +GG+L I GRF E A F+ ++ G+ + S Sbjct: 399 PPFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQS 458 Query: 184 MQVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHS-QPKSTVGTPAYIAPEVLLKKE 360 + +RDLKL+N +LD + +KI DFG K ++ K+ GTP YIAPE++ + Sbjct: 459 KGIIYRDLKLDNVMLD--SEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQP 516 Query: 361 YDGKIADVWSRGVTLYVML 417 Y GK D W+ GV LY ML Sbjct: 517 Y-GKSVDWWAFGVLLYEML 534
>KPCB_HUMAN (P05771) Protein kinase C beta type (EC 2.7.11.13) (PKC-beta)| (PKC-B) Length = 670 Score = 94.0 bits (232), Expect = 1e-19 Identities = 54/139 (38%), Positives = 76/139 (54%), Gaps = 1/139 (0%) Frame = +1 Query: 4 PPNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHS 183 PP + + T L VMEY +GG+L I GRF E A F+ ++ G+ + S Sbjct: 399 PPFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQS 458 Query: 184 MQVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHS-QPKSTVGTPAYIAPEVLLKKE 360 + +RDLKL+N +LD + +KI DFG K ++ K+ GTP YIAPE++ + Sbjct: 459 KGIIYRDLKLDNVMLD--SEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQP 516 Query: 361 YDGKIADVWSRGVTLYVML 417 Y GK D W+ GV LY ML Sbjct: 517 Y-GKSVDWWAFGVLLYEML 534
>MAPK2_MOUSE (P49138) MAP kinase-activated protein kinase 2 (EC 2.7.11.1)| (MAPK-activated protein kinase 2) (MAPKAP kinase 2) (MAPKAPK-2) (MK2) Length = 386 Score = 93.6 bits (231), Expect = 2e-19 Identities = 55/126 (43%), Positives = 76/126 (60%), Gaps = 4/126 (3%) Frame = +1 Query: 52 LAIVMEYASGGELFERICNAG--RFSEDEARFFFQQLLSGVSYCHSMQVCHRDLKLENTL 225 L IVME GGELF RI + G F+E EA + + + Y HS+ + HRD+K EN L Sbjct: 120 LLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPEN-L 178 Query: 226 LDGSTAPR--LKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYDGKIADVWSRGV 399 L S P LK+ DFG++K + H+ + TP Y+APEVL ++YD K D+WS GV Sbjct: 179 LYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYD-KSCDMWSLGV 237 Query: 400 TLYVML 417 +Y++L Sbjct: 238 IMYILL 243
>DAPK2_HUMAN (Q9UIK4) Death-associated protein kinase 2 (EC 2.7.11.1) (DAP| kinase 2) (DAP-kinase-related protein 1) (DRP-1) Length = 370 Score = 93.6 bits (231), Expect = 2e-19 Identities = 51/138 (36%), Positives = 79/138 (57%), Gaps = 2/138 (1%) Frame = +1 Query: 10 NIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSMQ 189 N+I +V T + +++E SGGELF+ + SE+EA F +Q+L GV+Y H+ + Sbjct: 85 NVITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEATSFIKQILDGVNYLHTKK 144 Query: 190 VCHRDLKLENTLL--DGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEY 363 + H DLK EN +L P +K+ DFG + + K+ GTP ++APE+ + E Sbjct: 145 IAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIEDGVEFKNIFGTPEFVAPEI-VNYEP 203 Query: 364 DGKIADVWSRGVTLYVML 417 G AD+WS GV Y++L Sbjct: 204 LGLEADMWSIGVITYILL 221
>MAPK2_CRILO (P49136) MAP kinase-activated protein kinase 2 (EC 2.7.11.1)| (MAPK-activated protein kinase 2) (MAPKAP kinase 2) (MAPKAPK-2) (P45-54 HSP27 kinase) (Fragment) Length = 329 Score = 93.6 bits (231), Expect = 2e-19 Identities = 55/126 (43%), Positives = 76/126 (60%), Gaps = 4/126 (3%) Frame = +1 Query: 52 LAIVMEYASGGELFERICNAG--RFSEDEARFFFQQLLSGVSYCHSMQVCHRDLKLENTL 225 L IVME GGELF RI + G F+E EA + + + Y HS+ + HRD+K EN L Sbjct: 63 LLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPEN-L 121 Query: 226 LDGSTAPR--LKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYDGKIADVWSRGV 399 L S P LK+ DFG++K + H+ + TP Y+APEVL ++YD K D+WS GV Sbjct: 122 LYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYD-KSCDMWSLGV 180 Query: 400 TLYVML 417 +Y++L Sbjct: 181 IMYILL 186
>KPCD_HUMAN (Q05655) Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta)| Length = 676 Score = 93.6 bits (231), Expect = 2e-19 Identities = 54/127 (42%), Positives = 73/127 (57%), Gaps = 1/127 (0%) Frame = +1 Query: 40 TPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSMQVCHRDLKLEN 219 T HL VME+ +GG+L I + GRF A F+ +++ G+ + HS + +RDLKL+N Sbjct: 419 TKDHLFFVMEFLNGGDLMYHIQDKGRFELYRATFYAAEIMCGLQFLHSKGIIYRDLKLDN 478 Query: 220 TLLDGSTAPRLKICDFGYSKSSVLHSQPKST-VGTPAYIAPEVLLKKEYDGKIADVWSRG 396 LLD +KI DFG K ++ ST GTP YIAPE+L +Y + D WS G Sbjct: 479 VLLDRD--GHIKIADFGMCKENIFGESRASTFCGTPDYIAPEILQGLKYTFSV-DWWSFG 535 Query: 397 VTLYVML 417 V LY ML Sbjct: 536 VLLYEML 542
>MAPK2_HUMAN (P49137) MAP kinase-activated protein kinase 2 (EC 2.7.11.1)| (MAPK-activated protein kinase 2) (MAPKAP kinase 2) (MAPKAPK-2) (MK2) Length = 400 Score = 93.6 bits (231), Expect = 2e-19 Identities = 55/126 (43%), Positives = 76/126 (60%), Gaps = 4/126 (3%) Frame = +1 Query: 52 LAIVMEYASGGELFERICNAG--RFSEDEARFFFQQLLSGVSYCHSMQVCHRDLKLENTL 225 L IVME GGELF RI + G F+E EA + + + Y HS+ + HRD+K EN L Sbjct: 134 LLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPEN-L 192 Query: 226 LDGSTAPR--LKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYDGKIADVWSRGV 399 L S P LK+ DFG++K + H+ + TP Y+APEVL ++YD K D+WS GV Sbjct: 193 LYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYD-KSCDMWSLGV 251 Query: 400 TLYVML 417 +Y++L Sbjct: 252 IMYILL 257
>SGK1_RABIT (Q9XT18) Serine/threonine-protein kinase Sgk1 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 1) Length = 431 Score = 93.6 bits (231), Expect = 2e-19 Identities = 53/127 (41%), Positives = 73/127 (57%), Gaps = 1/127 (0%) Frame = +1 Query: 40 TPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSMQVCHRDLKLEN 219 T L V++Y +GGELF + F E ARF+ ++ S + Y HS+ + +RDLK EN Sbjct: 168 TADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNIVYRDLKPEN 227 Query: 220 TLLDGSTAPRLKICDFGYSKSSVLHSQPKST-VGTPAYIAPEVLLKKEYDGKIADVWSRG 396 LLD + + + DFG K ++ H+ ST GTP Y+APEVL K+ YD + D W G Sbjct: 228 ILLD--SQGHIVLTDFGLCKENIEHNGTTSTFCGTPEYLAPEVLHKQPYD-RTVDWWCLG 284 Query: 397 VTLYVML 417 LY ML Sbjct: 285 AVLYEML 291
>SGK1_MOUSE (Q9WVC6) Serine/threonine-protein kinase Sgk1 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 1) Length = 431 Score = 93.6 bits (231), Expect = 2e-19 Identities = 53/127 (41%), Positives = 73/127 (57%), Gaps = 1/127 (0%) Frame = +1 Query: 40 TPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSMQVCHRDLKLEN 219 T L V++Y +GGELF + F E ARF+ ++ S + Y HS+ + +RDLK EN Sbjct: 168 TADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNIVYRDLKPEN 227 Query: 220 TLLDGSTAPRLKICDFGYSKSSVLHSQPKST-VGTPAYIAPEVLLKKEYDGKIADVWSRG 396 LLD + + + DFG K ++ H+ ST GTP Y+APEVL K+ YD + D W G Sbjct: 228 ILLD--SQGHIVLTDFGLCKENIEHNGTTSTFCGTPEYLAPEVLHKQPYD-RTVDWWCLG 284 Query: 397 VTLYVML 417 LY ML Sbjct: 285 AVLYEML 291
>KPSH1_PINFU (Q4KTY1) Serine/threonine-protein kinase H1 homolog (EC 2.7.11.1)| Length = 415 Score = 93.6 bits (231), Expect = 2e-19 Identities = 55/137 (40%), Positives = 80/137 (58%), Gaps = 2/137 (1%) Frame = +1 Query: 13 IIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSMQV 192 II+ EV T + +VME A+GGELF+RI G F+E +A +L GV Y H + + Sbjct: 135 IIQLIEVFETKDKVYMVMELATGGELFDRIIAKGSFTERDATRVLNMVLDGVKYLHGLGI 194 Query: 193 CHRDLKLENTL-LDGSTAPRLKICDFGYSKS-SVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 HRDLK EN L ++ I DFG S + + ++T GTP YIAPE++ +K Y Sbjct: 195 THRDLKPENLLYYHPGHDSKIMITDFGLSSTRKGPENFMRTTCGTPEYIAPEIIARKPYM 254 Query: 367 GKIADVWSRGVTLYVML 417 ++ D+W+ GV Y++L Sbjct: 255 CQV-DMWAVGVITYILL 270
>ULK2_HUMAN (Q8IYT8) Serine/threonine-protein kinase ULK2 (EC 2.7.11.1)| (Unc-51-like kinase 2) Length = 1036 Score = 93.6 bits (231), Expect = 2e-19 Identities = 51/143 (35%), Positives = 78/143 (54%), Gaps = 7/143 (4%) Frame = +1 Query: 10 NIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSMQ 189 NI+ +V P + +VMEY +GG+L + + G SED R F Q+ + + HS Sbjct: 67 NIVALYDVQELPNSVFLVMEYCNGGDLADYLQAKGTLSEDTIRVFLHQIAAAMRILHSKG 126 Query: 190 VCHRDLKLENTLL-------DGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVL 348 + HRDLK +N LL + R+KI DFG+++ + + G+P Y+APEV+ Sbjct: 127 IIHRDLKPQNILLSYANRRKSSVSGIRIKIADFGFARYLHSNMMAATLCGSPMYMAPEVI 186 Query: 349 LKKEYDGKIADVWSRGVTLYVML 417 + + YD K AD+WS G +Y L Sbjct: 187 MSQHYDAK-ADLWSIGTVIYQCL 208
>CDPK2_MAIZE (P49101) Calcium-dependent protein kinase 2 (EC 2.7.11.1) (CDPK 2)| Length = 513 Score = 93.6 bits (231), Expect = 2e-19 Identities = 57/138 (41%), Positives = 79/138 (57%), Gaps = 1/138 (0%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PNI+ F+ +++ +VME +GGELF+RI G ++E A + +++ V+ CH M Sbjct: 124 PNIVEFRGAYEDKSNVHVVMELCAGGELFDRIIAKGHYTERAAATICRAVVNVVNICHFM 183 Query: 187 QVCHRDLKLENTLL-DGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEY 363 V HRDLK EN LL LK DFG S + VG+ Y+APEV L++ Y Sbjct: 184 GVMHRDLKPENFLLATMEENAMLKATDFGLSVFIEEGKMYRDIVGSAYYVAPEV-LRRSY 242 Query: 364 DGKIADVWSRGVTLYVML 417 GK DVWS GV LY++L Sbjct: 243 -GKEIDVWSAGVILYILL 259
>TSSK4_MOUSE (Q9D411) Testis-specific serine/threonine-protein kinase 4 (EC| 2.7.11.1) (TSSK-4) (Testis-specific kinase 4) (TSK-4) Length = 328 Score = 93.6 bits (231), Expect = 2e-19 Identities = 56/151 (37%), Positives = 83/151 (54%), Gaps = 16/151 (10%) Frame = +1 Query: 13 IIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSMQV 192 +I F + I T + + I++E A GG++ E I G +E A +F Q+ G++Y HS + Sbjct: 85 LINFYQAIETTSRVYIILELAQGGDVLEWIQRYGACAETLAGKWFSQMALGIAYLHSKGI 144 Query: 193 CHRDLKLENTLLDGSTAPRLKICDFGYSK----SSVLHSQP------------KSTVGTP 324 HRDLKLEN LLD +KI DFG++K S +HS P ++ G+ Sbjct: 145 VHRDLKLENLLLD--KRENVKISDFGFAKMVPSSQPVHSSPSYRQMNSLSHLSQTYCGSF 202 Query: 325 AYIAPEVLLKKEYDGKIADVWSRGVTLYVML 417 AY PE+LL Y+ ++D WS GV LY ++ Sbjct: 203 AYACPEILLGLPYNPFLSDTWSMGVILYTLV 233
>MAPK2_DROME (P49071) MAP kinase-activated protein kinase 2 (EC 2.7.11.1)| (MAPK-activated protein kinase 2) (MAPKAP kinase 2) (MAPKAPK-2) Length = 359 Score = 93.6 bits (231), Expect = 2e-19 Identities = 54/126 (42%), Positives = 77/126 (61%), Gaps = 4/126 (3%) Frame = +1 Query: 52 LAIVMEYASGGELFERICNA--GRFSEDEARFFFQQLLSGVSYCHSMQVCHRDLKLENTL 225 L +VME GGELF+RI + G F+E EA ++ + V Y HS + HRDLK EN L Sbjct: 90 LLVVMECMEGGELFQRIQDKADGAFTEREAAQIMHEICAAVDYLHSRDIAHRDLKPEN-L 148 Query: 226 LDGSTAPR--LKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYDGKIADVWSRGV 399 L +T P LK+ DFG++K + ++ TP Y+APEVL ++YD K D+WS GV Sbjct: 149 LYTTTQPNATLKLTDFGFAKETFTSYTLQTPCYTPYYVAPEVLGPEKYD-KSCDIWSLGV 207 Query: 400 TLYVML 417 +Y+++ Sbjct: 208 VMYIIM 213
>SGK1_RAT (Q06226) Serine/threonine-protein kinase Sgk1 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 1) Length = 430 Score = 93.6 bits (231), Expect = 2e-19 Identities = 53/127 (41%), Positives = 73/127 (57%), Gaps = 1/127 (0%) Frame = +1 Query: 40 TPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSMQVCHRDLKLEN 219 T L V++Y +GGELF + F E ARF+ ++ S + Y HS+ + +RDLK EN Sbjct: 168 TADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNIVYRDLKPEN 227 Query: 220 TLLDGSTAPRLKICDFGYSKSSVLHSQPKST-VGTPAYIAPEVLLKKEYDGKIADVWSRG 396 LLD + + + DFG K ++ H+ ST GTP Y+APEVL K+ YD + D W G Sbjct: 228 ILLD--SQGHIVLTDFGLCKENIEHNGTTSTFCGTPEYLAPEVLHKQPYD-RTVDWWCLG 284 Query: 397 VTLYVML 417 LY ML Sbjct: 285 AVLYEML 291
>CDPK4_PLAF7 (Q8IBS5) Calcium-dependent protein kinase 4 (EC 2.7.11.1)| Length = 527 Score = 93.2 bits (230), Expect = 2e-19 Identities = 56/138 (40%), Positives = 77/138 (55%), Gaps = 2/138 (1%) Frame = +1 Query: 10 NIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSMQ 189 NI++ E + +V + +GGELF+ I + RF E +A +Q+LSG++Y H Sbjct: 128 NIMKLYEFFEDNNYYYLVSDVYTGGELFDEIISRKRFYEIDAARIIKQILSGITYMHKNN 187 Query: 190 VCHRDLKLENTLLDGSTAPR--LKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEY 363 V HRDLK EN LL+ +KI DFG S + K +GT YIAP+V L Y Sbjct: 188 VVHRDLKPENILLETKNKEDMIIKIIDFGLSTHFEYSKKMKDKIGTAYYIAPDV-LHGTY 246 Query: 364 DGKIADVWSRGVTLYVML 417 D K D+WS GV LY++L Sbjct: 247 DEK-CDIWSCGVILYILL 263
>KPCT_HUMAN (Q04759) Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta)| Length = 706 Score = 93.2 bits (230), Expect = 2e-19 Identities = 53/127 (41%), Positives = 76/127 (59%), Gaps = 1/127 (0%) Frame = +1 Query: 40 TPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSMQVCHRDLKLEN 219 T +L VMEY +GG+L I + +F A F+ +++ G+ + HS + +RDLKL+N Sbjct: 450 TKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILGLQFLHSKGIVYRDLKLDN 509 Query: 220 TLLDGSTAPRLKICDFGYSKSSVLHSQPKST-VGTPAYIAPEVLLKKEYDGKIADVWSRG 396 LLD +KI DFG K ++L +T GTP YIAPE+LL ++Y+ + D WS G Sbjct: 510 ILLDKD--GHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPEILLGQKYNHSV-DWWSFG 566 Query: 397 VTLYVML 417 V LY ML Sbjct: 567 VLLYEML 573
>CHK1_USTMA (P0C198) Serine/threonine-protein kinase CHK1 (EC 2.7.11.1)| (Checkpoint kinase 1) Length = 662 Score = 93.2 bits (230), Expect = 2e-19 Identities = 58/141 (41%), Positives = 79/141 (56%), Gaps = 10/141 (7%) Frame = +1 Query: 25 KEVILTPTH-------LAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHS 183 ++++ +P+H L +V+E +GG+LF++I ED A F+FQQLL+G+ Y HS Sbjct: 127 QQMLSSPSHDQNYVPGLYMVLELGAGGDLFDKIAPDYGVEEDLAHFYFQQLLAGLEYIHS 186 Query: 184 MQVCHRDLKLENTLLDGSTAPRLKICDFGYS---KSSVLHSQPKSTVGTPAYIAPEVLLK 354 V HRD+K EN LLD LKI DFG K + G+ YIAPE + Sbjct: 187 QGVTHRDIKPENMLLDAE--GNLKIADFGLCSVYKYKGKERELTGACGSLPYIAPE-MNG 243 Query: 355 KEYDGKIADVWSRGVTLYVML 417 K Y G+ DVWS GV L+ ML Sbjct: 244 KPYRGEPVDVWSSGVVLFAML 264
>KS6A1_RAT (Q63531) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1)| (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 735 Score = 93.2 bits (230), Expect = 2e-19 Identities = 62/143 (43%), Positives = 80/143 (55%), Gaps = 6/143 (4%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PNII K+V H+ +V E GGEL ++I FSE EA F + V Y HS Sbjct: 470 PNIITLKDVYDDSKHVYLVTELMRGGELLDKILRQKFFSEREASFVLYTISKTVEYLHSQ 529 Query: 187 QVCHRDLKLENTL-LDGSTAPR-LKICDFGYSKSSVLHSQPKSTVGTPAY----IAPEVL 348 V HRDLK N L +D S P L+ICDFG++K L ++ + TP Y +APEVL Sbjct: 530 GVVHRDLKPSNILYVDESGNPECLRICDFGFAKQ--LRAE-NGLLMTPCYTANFVAPEVL 586 Query: 349 LKKEYDGKIADVWSRGVTLYVML 417 ++ YD + D+WS GV LY ML Sbjct: 587 KRQGYD-EGCDIWSLGVLLYTML 608 Score = 87.0 bits (214), Expect = 2e-17 Identities = 47/138 (34%), Positives = 80/138 (57%), Gaps = 1/138 (0%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P +++ T L +++++ GG+LF R+ F+E++ +F+ +L G+ + HS+ Sbjct: 122 PFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLHSL 181 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPK-STVGTPAYIAPEVLLKKEY 363 + +RDLK EN LLD +K+ DFG SK ++ H + S GT Y+APEV+ ++ + Sbjct: 182 GIIYRDLKPENILLD--EEGHIKLTDFGLSKEAIDHEKKAYSFCGTVEYMAPEVVNRQGH 239 Query: 364 DGKIADVWSRGVTLYVML 417 AD WS GV ++ ML Sbjct: 240 THS-ADWWSYGVLMFEML 256
>YPK2_YEAST (P18961) Serine/threonine-protein kinase YPK2/YKR2 (EC 2.7.11.1)| Length = 677 Score = 93.2 bits (230), Expect = 2e-19 Identities = 53/138 (38%), Positives = 78/138 (56%), Gaps = 1/138 (0%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P I+ K +P L +V+ + +GGELF + + GRFS +RF+ +LL + H + Sbjct: 402 PFIVPLKFSFQSPEKLYLVLAFINGGELFYHLQHEGRFSLARSRFYIAELLCALDSLHKL 461 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKST-VGTPAYIAPEVLLKKEY 363 V +RDLK EN LLD + +CDFG K ++ + T GTP Y+APE+LL + Y Sbjct: 462 DVIYRDLKPENILLD--YQGHIALCDFGLCKLNMKDNDKTDTFCGTPEYLAPEILLGQGY 519 Query: 364 DGKIADVWSRGVTLYVML 417 K D W+ G+ LY M+ Sbjct: 520 T-KTVDWWTLGILLYEMM 536
>KPK19_ARATH (Q39030) Serine/threonine-protein kinase AtPK19 (EC 2.7.11.1)| (Ribosomal-protein S6 kinase homolog) Length = 471 Score = 93.2 bits (230), Expect = 2e-19 Identities = 52/137 (37%), Positives = 80/137 (58%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P I++ K T L +V+++ +GG LF ++ + G F ED AR + +++S VS+ H Sbjct: 198 PFIVQLKYSFQTKYRLYLVLDFINGGHLFFQLYHQGLFREDLARVYTAEIVSAVSHLHEK 257 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 + HRDLK EN L+D + + DFG +K +++ S GT Y+APE++ K +D Sbjct: 258 GIMHRDLKPENILMD--VDGHVMLTDFGLAKEFEENTRSNSMCGTTEYMAPEIVRGKGHD 315 Query: 367 GKIADVWSRGVTLYVML 417 K AD WS G+ LY ML Sbjct: 316 -KAADWWSVGILLYEML 331
>KPCL_RAT (Q64617) Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta)| (PKC-L) Length = 683 Score = 92.8 bits (229), Expect = 3e-19 Identities = 52/127 (40%), Positives = 72/127 (56%), Gaps = 1/127 (0%) Frame = +1 Query: 40 TPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSMQVCHRDLKLEN 219 TP L VME+ +GG+L I + RF E ARF+ +++S + + H + +RDLKL+N Sbjct: 425 TPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIISALMFLHEKGIIYRDLKLDN 484 Query: 220 TLLDGSTAPRLKICDFGYSKSSVLHSQPKST-VGTPAYIAPEVLLKKEYDGKIADVWSRG 396 LLD K+ DFG K + + +T GTP YIAPE+L + Y G D W+ G Sbjct: 485 VLLDHE--GHCKLADFGMCKEGICNGVTTATFCGTPDYIAPEILQEMLY-GPAVDWWAMG 541 Query: 397 VTLYVML 417 V LY ML Sbjct: 542 VLLYEML 548
>KPCL_MOUSE (P23298) Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta)| (PKC-L) Length = 683 Score = 92.8 bits (229), Expect = 3e-19 Identities = 52/127 (40%), Positives = 72/127 (56%), Gaps = 1/127 (0%) Frame = +1 Query: 40 TPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSMQVCHRDLKLEN 219 TP L VME+ +GG+L I + RF E ARF+ +++S + + H + +RDLKL+N Sbjct: 425 TPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIISALMFLHEKGIIYRDLKLDN 484 Query: 220 TLLDGSTAPRLKICDFGYSKSSVLHSQPKST-VGTPAYIAPEVLLKKEYDGKIADVWSRG 396 LLD K+ DFG K + + +T GTP YIAPE+L + Y G D W+ G Sbjct: 485 VLLDHE--GHCKLADFGMCKEGICNGVTTATFCGTPDYIAPEILQEMLY-GPAVDWWAMG 541 Query: 397 VTLYVML 417 V LY ML Sbjct: 542 VLLYEML 548
>KS6A1_MOUSE (P18653) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1)| (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 724 Score = 92.8 bits (229), Expect = 3e-19 Identities = 61/143 (42%), Positives = 80/143 (55%), Gaps = 6/143 (4%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PNII K+V H+ +V E GGEL ++I FSE EA F + V Y HS Sbjct: 459 PNIITLKDVYDDGKHVYLVTELMRGGELLDKILRQKFFSEREASFVLHTISKTVEYLHSQ 518 Query: 187 QVCHRDLKLENTL-LDGSTAPR-LKICDFGYSKSSVLHSQPKSTVGTPAY----IAPEVL 348 V HRDLK N L +D S P L+ICDFG++K L ++ + TP Y +APEVL Sbjct: 519 GVVHRDLKPSNILYVDESGNPECLRICDFGFAKQ--LRAE-NGLLMTPCYTANFVAPEVL 575 Query: 349 LKKEYDGKIADVWSRGVTLYVML 417 ++ YD + D+WS G+ LY ML Sbjct: 576 KRQGYD-EGCDIWSLGILLYTML 597 Score = 83.2 bits (204), Expect = 2e-16 Identities = 45/134 (33%), Positives = 77/134 (57%), Gaps = 1/134 (0%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P +++ T L +++++ GG+LF R+ F+E++ +F+ +L G+ + HS+ Sbjct: 122 PFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLHSL 181 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPK-STVGTPAYIAPEVLLKKEY 363 + +RDLK EN LLD +K+ DFG SK ++ H + S GT Y+APEV+ ++ + Sbjct: 182 GIIYRDLKPENILLD--EEGHIKLTDFGLSKEAIDHEKKAYSFCGTVEYMAPEVVNRQGH 239 Query: 364 DGKIADVWSRGVTL 405 AD WS GV + Sbjct: 240 THS-ADWWSYGVLM 252
>KPCL_HUMAN (P24723) Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta)| (PKC-L) Length = 682 Score = 92.8 bits (229), Expect = 3e-19 Identities = 52/127 (40%), Positives = 72/127 (56%), Gaps = 1/127 (0%) Frame = +1 Query: 40 TPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSMQVCHRDLKLEN 219 TP L VME+ +GG+L I + RF E ARF+ +++S + + H + +RDLKL+N Sbjct: 424 TPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIISALMFLHDKGIIYRDLKLDN 483 Query: 220 TLLDGSTAPRLKICDFGYSKSSVLHSQPKST-VGTPAYIAPEVLLKKEYDGKIADVWSRG 396 LLD K+ DFG K + + +T GTP YIAPE+L + Y G D W+ G Sbjct: 484 VLLDHE--GHCKLADFGMCKEGICNGVTTATFCGTPDYIAPEILQEMLY-GPAVDWWAMG 540 Query: 397 VTLYVML 417 V LY ML Sbjct: 541 VLLYEML 547
>MYLK2_HUMAN (Q9H1R3) Myosin light chain kinase 2, skeletal/cardiac muscle (EC| 2.7.11.18) (MLCK2) Length = 595 Score = 92.8 bits (229), Expect = 3e-19 Identities = 51/137 (37%), Positives = 77/137 (56%), Gaps = 1/137 (0%) Frame = +1 Query: 10 NIIRFKEVILTPTHLAIVMEYASGGELFERICNAG-RFSEDEARFFFQQLLSGVSYCHSM 186 N+I+ I TP + + MEY GGELFERI + +E + F +Q+ G+ + H M Sbjct: 340 NLIQLYAAIETPHEIVLFMEYIEGGELFERIVDEDYHLTEVDTMVFVRQICDGILFMHKM 399 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 +V H DLK EN L +T +KI DFG ++ + + K GTP +++PEV+ + Sbjct: 400 RVLHLDLKPENILCVNTTGHLVKIIDFGLARRYNPNEKLKVNFGTPEFLSPEVVNYDQIS 459 Query: 367 GKIADVWSRGVTLYVML 417 K D+WS GV Y++L Sbjct: 460 DK-TDMWSMGVITYMLL 475
>DCAK2_MOUSE (Q6PGN3) Serine/threonine-protein kinase DCAMKL2 (EC 2.7.11.1)| (Doublecortin-like and CAM kinase-like 2) Length = 756 Score = 92.8 bits (229), Expect = 3e-19 Identities = 52/141 (36%), Positives = 83/141 (58%), Gaps = 4/141 (2%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PNII E + T T L +VME GG+LF+ I ++ +++E + L + + Y HS+ Sbjct: 449 PNIIMLVEEMETATDLFLVMELVKGGDLFDAITSSTKYTERDGSAMVYNLANALRYLHSL 508 Query: 187 QVCHRDLKLENTLL----DGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLK 354 + HRD+K EN L+ DG+ + LK+ DFG ++V+ + GTP Y+APE++ + Sbjct: 509 SIVHRDIKPENLLVCEYPDGTKS--LKLGDFGL--ATVVEGPLYTVCGTPTYVAPEIIAE 564 Query: 355 KEYDGKIADVWSRGVTLYVML 417 Y K+ DVW+ GV Y++L Sbjct: 565 TGYGLKV-DVWAAGVITYILL 584
>KCC1_METAN (O14408) Calcium/calmodulin-dependent protein kinase (EC 2.7.11.17)| Length = 382 Score = 92.4 bits (228), Expect = 4e-19 Identities = 53/139 (38%), Positives = 83/139 (59%), Gaps = 2/139 (1%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P+I++F + + IV + A+GGELF+RIC+ G+F+E +A +Q+++ V Y H Sbjct: 77 PHIVKFVDWFESRDKFYIVTQLATGGELFDRICDQGKFTEVDASQTIRQIMTAVDYLHDN 136 Query: 187 QVCHRDLKLENTL-LDGSTAPRLKICDFGYSKSSVLHSQPKSTV-GTPAYIAPEVLLKKE 360 V HRDLK EN L + L + DFG +K+ + + +T+ G+ Y APEV+ +K Sbjct: 137 DVVHRDLKPENLLYVTRDPDSDLVLADFGITKTLDIKEETLTTMAGSFGYAAPEVMEQKG 196 Query: 361 YDGKIADVWSRGVTLYVML 417 + GK D+WS GV Y +L Sbjct: 197 H-GKPVDMWSMGVITYTLL 214
>KPCD_CANFA (Q5PU49) Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta)| Length = 674 Score = 92.4 bits (228), Expect = 4e-19 Identities = 52/127 (40%), Positives = 74/127 (58%), Gaps = 1/127 (0%) Frame = +1 Query: 40 TPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSMQVCHRDLKLEN 219 T HL VME+ +GG+L I + GRF A F+ +++ G+ + H+ + +RDLKL+N Sbjct: 417 TKDHLFFVMEFLNGGDLMYHIQDKGRFELYRATFYAAEIVCGLQFLHNKGIIYRDLKLDN 476 Query: 220 TLLDGSTAPRLKICDFGYSKSSVLHSQPKST-VGTPAYIAPEVLLKKEYDGKIADVWSRG 396 +LD +KI DFG K ++ + ST GTP YIAPE+L +Y + D WS G Sbjct: 477 VMLDQD--GHIKIADFGMCKENIFGEKQASTFCGTPDYIAPEILQGLKYSFSV-DWWSFG 533 Query: 397 VTLYVML 417 V LY ML Sbjct: 534 VLLYEML 540
>ST17A_HUMAN (Q9UEE5) Serine/threonine-protein kinase 17A (EC 2.7.11.1) (DAP| kinase-related apoptosis-inducing protein kinase 1) Length = 414 Score = 92.4 bits (228), Expect = 4e-19 Identities = 57/143 (39%), Positives = 81/143 (56%), Gaps = 6/143 (4%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGR---FSEDEARFFFQQLLSGVSYC 177 P +I EV T + + +V+EYA+GGE+F++ C A R F E + + +Q+L GV + Sbjct: 119 PWVINLHEVYETASEMILVLEYAAGGEIFDQ-CVADREEAFKEKDVQRLMRQILEGVHFL 177 Query: 178 HSMQVCHRDLKLENTLLDG-STAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLK 354 H+ V H DLK +N LL S +KI DFG S+ + + +GTP Y+APE+L Sbjct: 178 HTRDVVHLDLKPQNILLTSESPLGDIKIVDFGLSRILKNSEELREIMGTPEYVAPEIL-- 235 Query: 355 KEYD--GKIADVWSRGVTLYVML 417 YD D+WS GV YVML Sbjct: 236 -SYDPISMATDMWSIGVLTYVML 257
>CDC5_YEAST (P32562) Cell cycle serine/threonine-protein kinase CDC5/MSD2 (EC| 2.7.11.21) Length = 705 Score = 92.4 bits (228), Expect = 4e-19 Identities = 55/139 (39%), Positives = 75/139 (53%), Gaps = 2/139 (1%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PNI++F + +++ I++E G L E + +E E RFF Q+ + Y HS Sbjct: 139 PNIVQFIDCFEDDSNVYILLEICPNGSLMELLKRRKVLTEPEVRFFTTQICGAIKYMHSR 198 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTV-GTPAYIAPEVLLKKEY 363 +V HRDLKL N D + LKI DFG + S+ K T+ GTP YIAPEVL+ K Sbjct: 199 RVIHRDLKLGNIFFDSNY--NLKIGDFGLAAVLANESERKYTICGTPNYIAPEVLMGKHS 256 Query: 364 DGKI-ADVWSRGVTLYVML 417 D+WS GV LY +L Sbjct: 257 GHSFEVDIWSLGVMLYALL 275
>HAL4_YEAST (P25333) Serine/threonine-protein kinase HAL4/SAT4 (EC 2.7.11.1)| (Halotolerence protein 4) Length = 603 Score = 92.4 bits (228), Expect = 4e-19 Identities = 55/125 (44%), Positives = 71/125 (56%), Gaps = 7/125 (5%) Frame = +1 Query: 61 VMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSMQVCHRDLKLENTLL--DG 234 VMEY +GG+LF + AG+ EA FF+QL+ GV Y H M VCHRDLK EN LL DG Sbjct: 402 VMEYCAGGDLFTLVVAAGKLEYMEADCFFKQLIRGVVYMHEMGVCHRDLKPENLLLTHDG 461 Query: 235 STAPRLKICDFGYSKSSVLHSQPK-----STVGTPAYIAPEVLLKKEYDGKIADVWSRGV 399 LKI DFG S+ + + G+ YIAPE +K+E+D + D+W+ GV Sbjct: 462 V----LKITDFGNSECFKMAWEKNIHLSGGVCGSSPYIAPEEYIKEEFDPRPVDIWACGV 517 Query: 400 TLYVM 414 M Sbjct: 518 IYMAM 522
>CDPK2_ORYSA (P53683) Calcium-dependent protein kinase, isoform 2 (EC 2.7.11.1)| (CDPK 2) Length = 533 Score = 92.4 bits (228), Expect = 4e-19 Identities = 57/137 (41%), Positives = 78/137 (56%), Gaps = 1/137 (0%) Frame = +1 Query: 10 NIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSMQ 189 NI+ F+ +++ +VME +GGELF+RI G +SE A + +++ V+ CH M Sbjct: 145 NIVEFRGAYEDKSNVHVVMELCAGGELFDRIIAKGHYSERAAATICRAVVNVVNICHFMG 204 Query: 190 VCHRDLKLENTLL-DGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 V HRDLK EN LL LK DFG S + VG+ Y+APEV L++ Y Sbjct: 205 VMHRDLKPENFLLATKEENAMLKATDFGLSVFIEEGKMYRDIVGSAYYVAPEV-LRRNY- 262 Query: 367 GKIADVWSRGVTLYVML 417 GK DVWS GV LY++L Sbjct: 263 GKEIDVWSAGVILYILL 279
>CHK2_MOUSE (Q9Z265) Serine/threonine-protein kinase Chk2 (EC 2.7.11.1)| Length = 546 Score = 92.4 bits (228), Expect = 4e-19 Identities = 57/140 (40%), Positives = 74/140 (52%), Gaps = 3/140 (2%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P II+ K+V + IV+E GGELF+R+ R E + +F Q+L V Y H Sbjct: 287 PCIIKIKDVFDAEDYY-IVLELMEGGELFDRVVGNKRLKEATCKLYFYQMLVAVQYLHEN 345 Query: 187 QVCHRDLKLENTLLDGSTAPRL-KICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEY 363 + HRDLK EN LL L KI DFG SK S ++ GTP Y+APEVL+ Sbjct: 346 GIIHRDLKPENVLLSSQEEDCLIKITDFGQSKILGETSLMRTLCGTPTYLAPEVLVSNGT 405 Query: 364 DG--KIADVWSRGVTLYVML 417 G + D WS GV L++ L Sbjct: 406 AGYSRAVDCWSLGVILFICL 425
>MYLK2_RABIT (P07313) Myosin light chain kinase 2, skeletal/cardiac muscle (EC| 2.7.11.18) (MLCK2) Length = 607 Score = 92.4 bits (228), Expect = 4e-19 Identities = 51/137 (37%), Positives = 77/137 (56%), Gaps = 1/137 (0%) Frame = +1 Query: 10 NIIRFKEVILTPTHLAIVMEYASGGELFERICNAG-RFSEDEARFFFQQLLSGVSYCHSM 186 N+I+ I TP + + MEY GGELFERI + +E + F +Q+ G+ + H M Sbjct: 352 NLIQLYAAIETPHEIVLFMEYIEGGELFERIVDEDYHLTEVDTMVFVRQICDGILFMHKM 411 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 +V H DLK EN L +T +KI DFG ++ + + K GTP +++PEV+ + Sbjct: 412 RVLHLDLKPENILCVNTTGHLVKIIDFGLARRYNPNEKLKVNFGTPEFLSPEVVNYDQIS 471 Query: 367 GKIADVWSRGVTLYVML 417 K D+WS GV Y++L Sbjct: 472 DK-TDMWSLGVITYMLL 487
>KPCD_MOUSE (P28867) Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta)| Length = 674 Score = 92.0 bits (227), Expect = 5e-19 Identities = 53/127 (41%), Positives = 73/127 (57%), Gaps = 1/127 (0%) Frame = +1 Query: 40 TPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSMQVCHRDLKLEN 219 T HL VME+ +GG+L I + GRF A F+ +++ G+ + HS + +RDLKL+N Sbjct: 417 TKDHLFFVMEFLNGGDLMFHIQDKGRFELYRATFYAAEIICGLQFLHSKGIIYRDLKLDN 476 Query: 220 TLLDGSTAPRLKICDFGYSKSSVLHSQPKST-VGTPAYIAPEVLLKKEYDGKIADVWSRG 396 +LD +KI DFG K ++ ST GTP YIAPE+L +Y + D WS G Sbjct: 477 VMLDRD--GHIKIADFGMCKENIFGEGRASTFCGTPDYIAPEILQGLKYSFSV-DWWSFG 533 Query: 397 VTLYVML 417 V LY ML Sbjct: 534 VLLYEML 540
>KIN1_YEAST (P13185) Protein kinase KIN1 (EC 2.7.11.1)| Length = 1064 Score = 92.0 bits (227), Expect = 5e-19 Identities = 50/137 (36%), Positives = 74/137 (54%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P+I R E+ H ++ EY SGG+L + I G E +AR F + + S + Y H+ Sbjct: 204 PHICRLFEMCTLSNHFYMLFEYVSGGQLLDYIIQHGSIREHQARKFARGIASALIYLHAN 263 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD 366 + HRDLK+EN ++ S+ +KI DFG S Q + G+ + APE+L Y Sbjct: 264 NIVHRDLKIENIMISDSS--EIKIIDFGLSNIYDSRKQLHTFCGSLYFAAPELLKANPYT 321 Query: 367 GKIADVWSRGVTLYVML 417 G DVWS GV L+V++ Sbjct: 322 GPEVDVWSFGVVLFVLV 338
>KS6A1_HUMAN (Q15418) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1)| (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 735 Score = 92.0 bits (227), Expect = 5e-19 Identities = 61/143 (42%), Positives = 80/143 (55%), Gaps = 6/143 (4%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PNII K+V H+ +V E GGEL ++I FSE EA F + V Y HS Sbjct: 470 PNIITLKDVYDDGKHVYLVTELMRGGELLDKILRQKFFSEREASFVLHTIGKTVEYLHSQ 529 Query: 187 QVCHRDLKLENTL-LDGSTAPR-LKICDFGYSKSSVLHSQPKSTVGTPAY----IAPEVL 348 V HRDLK N L +D S P L+ICDFG++K L ++ + TP Y +APEVL Sbjct: 530 GVVHRDLKPSNILYVDESGNPECLRICDFGFAKQ--LRAE-NGLLMTPCYTANFVAPEVL 586 Query: 349 LKKEYDGKIADVWSRGVTLYVML 417 ++ YD + D+WS G+ LY ML Sbjct: 587 KRQGYD-EGCDIWSLGILLYTML 608 Score = 87.4 bits (215), Expect = 1e-17 Identities = 47/138 (34%), Positives = 80/138 (57%), Gaps = 1/138 (0%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P +++ T L +++++ GG+LF R+ F+E++ +F+ +L G+ + HS+ Sbjct: 122 PFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLHSL 181 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPK-STVGTPAYIAPEVLLKKEY 363 + +RDLK EN LLD +K+ DFG SK ++ H + S GT Y+APEV+ ++ + Sbjct: 182 GIIYRDLKPENILLD--EEGHIKLTDFGLSKEAIDHEKKAYSFCGTVEYMAPEVVNRQGH 239 Query: 364 DGKIADVWSRGVTLYVML 417 AD WS GV ++ ML Sbjct: 240 SHS-ADWWSYGVLMFEML 256
>KCC2B_RAT (P08413) Calcium/calmodulin-dependent protein kinase type II beta| chain (EC 2.7.11.17) (CaM-kinase II beta chain) (CaM kinase II beta subunit) (CaMK-II beta subunit) Length = 542 Score = 91.7 bits (226), Expect = 6e-19 Identities = 56/138 (40%), Positives = 75/138 (54%), Gaps = 2/138 (1%) Frame = +1 Query: 10 NIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSMQ 189 NI+R + I +V + +GGELFE I +SE +A QQ+L V +CH M Sbjct: 72 NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMG 131 Query: 190 VCHRDLKLENTLLDGS-TAPRLKICDFGYSKSSVLHSQP-KSTVGTPAYIAPEVLLKKEY 363 V HRDLK EN LL +K+ DFG + Q GTP Y++PEVL K+ Y Sbjct: 132 VVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEAY 191 Query: 364 DGKIADVWSRGVTLYVML 417 GK D+W+ GV LY++L Sbjct: 192 -GKPVDIWACGVILYILL 208
>KCC2B_MOUSE (P28652) Calcium/calmodulin-dependent protein kinase type II beta| chain (EC 2.7.11.17) (CaM-kinase II beta chain) (CaM kinase II beta subunit) (CaMK-II beta subunit) Length = 542 Score = 91.7 bits (226), Expect = 6e-19 Identities = 56/138 (40%), Positives = 75/138 (54%), Gaps = 2/138 (1%) Frame = +1 Query: 10 NIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSMQ 189 NI+R + I +V + +GGELFE I +SE +A QQ+L V +CH M Sbjct: 72 NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMG 131 Query: 190 VCHRDLKLENTLLDGS-TAPRLKICDFGYSKSSVLHSQP-KSTVGTPAYIAPEVLLKKEY 363 V HRDLK EN LL +K+ DFG + Q GTP Y++PEVL K+ Y Sbjct: 132 VVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEAY 191 Query: 364 DGKIADVWSRGVTLYVML 417 GK D+W+ GV LY++L Sbjct: 192 -GKPVDIWACGVILYILL 208
>KPCT_MOUSE (Q02111) Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta)| Length = 707 Score = 91.7 bits (226), Expect = 6e-19 Identities = 52/127 (40%), Positives = 76/127 (59%), Gaps = 1/127 (0%) Frame = +1 Query: 40 TPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSMQVCHRDLKLEN 219 T +L VMEY +GG+L I + +F A F+ +++ G+ + HS + +RDLKL+N Sbjct: 450 TKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEVILGLQFLHSKGIVYRDLKLDN 509 Query: 220 TLLDGSTAPRLKICDFGYSKSSVLHSQPKST-VGTPAYIAPEVLLKKEYDGKIADVWSRG 396 LLD +KI DFG K ++L +T GTP YIAPE+LL ++Y+ + D WS G Sbjct: 510 ILLDRD--GHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPEILLGQKYNHSV-DWWSFG 566 Query: 397 VTLYVML 417 V +Y ML Sbjct: 567 VLVYEML 573
>KPCA_MOUSE (P20444) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 91.7 bits (226), Expect = 6e-19 Identities = 52/139 (37%), Positives = 75/139 (53%), Gaps = 1/139 (0%) Frame = +1 Query: 4 PPNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHS 183 PP + + T L VMEY +GG+L I G+F E +A F+ ++ G+ + H Sbjct: 396 PPFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHK 455 Query: 184 MQVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKST-VGTPAYIAPEVLLKKE 360 + +RDLKL N +L ++ +KI DFG K ++ T GTP YIAPE++ + Sbjct: 456 RGIIYRDLKLNNVML--NSEGHIKIADFGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQP 513 Query: 361 YDGKIADVWSRGVTLYVML 417 Y GK D W+ GV LY ML Sbjct: 514 Y-GKSVDWWAYGVLLYEML 531
>RAD53_YEAST (P22216) Serine/threonine-protein kinase RAD53 (EC 2.7.11.1)| (Serine-protein kinase 1) Length = 821 Score = 91.7 bits (226), Expect = 6e-19 Identities = 54/149 (36%), Positives = 78/149 (52%), Gaps = 12/149 (8%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P I+R K +VME+ SGG+L + + G ED R +Q+L+ + Y HSM Sbjct: 254 PRIVRLKGFYEDTESYYMVMEFVSGGDLMDFVAAHGAVGEDAGREISRQILTAIKYIHSM 313 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKK--- 357 + HRDLK +N L++ +KI DFG +K S K+ GT AY+APEV+ K Sbjct: 314 GISHRDLKPDNILIEQDDPVLVKITDFGLAKVQGNGSFMKTFCGTLAYVAPEVIRGKDTS 373 Query: 358 ----EYD-----GKIADVWSRGVTLYVML 417 EY+ + D+WS G +YV+L Sbjct: 374 VSPDEYEERNEYSSLVDMWSMGCLVYVIL 402
>KCC2B_HUMAN (Q13554) Calcium/calmodulin-dependent protein kinase type II beta| chain (EC 2.7.11.17) (CaM-kinase II beta chain) (CaM kinase II beta subunit) (CaMK-II beta subunit) Length = 664 Score = 91.7 bits (226), Expect = 6e-19 Identities = 56/138 (40%), Positives = 75/138 (54%), Gaps = 2/138 (1%) Frame = +1 Query: 10 NIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSMQ 189 NI+R + I +V + +GGELFE I +SE +A QQ+L V +CH M Sbjct: 72 NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMG 131 Query: 190 VCHRDLKLENTLLDGS-TAPRLKICDFGYSKSSVLHSQP-KSTVGTPAYIAPEVLLKKEY 363 V HRDLK EN LL +K+ DFG + Q GTP Y++PEVL K+ Y Sbjct: 132 VVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEAY 191 Query: 364 DGKIADVWSRGVTLYVML 417 GK D+W+ GV LY++L Sbjct: 192 -GKPVDIWACGVILYILL 208
>PRKX_HUMAN (P51817) Serine/threonine-protein kinase PRKX (EC 2.7.11.1)| (Protein kinase PKX1) Length = 358 Score = 91.7 bits (226), Expect = 6e-19 Identities = 48/122 (39%), Positives = 73/122 (59%) Frame = +1 Query: 52 LAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSMQVCHRDLKLENTLLD 231 L ++MEY GGELF + N GRFS F+ +++ + Y HS ++ +RDLK EN LLD Sbjct: 122 LYMLMEYVPGGELFSYLRNRGRFSSTTGLFYSAEIICAIEYLHSKEIVYRDLKPENILLD 181 Query: 232 GSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYDGKIADVWSRGVTLYV 411 +K+ DFG++K V + + GTP Y+APEV+ K + G+ D W+ G+ ++ Sbjct: 182 RD--GHIKLTDFGFAKKLV--DRTWTLCGTPEYLAPEVIQSKGH-GRAVDWWALGILIFE 236 Query: 412 ML 417 ML Sbjct: 237 ML 238
>CCAMK_LILLO (Q43531) Calcium and calcium/calmodulin-dependent| serine/threonine-protein kinase (EC 2.7.11.17) (LlCCaMK) Length = 520 Score = 91.7 bits (226), Expect = 6e-19 Identities = 53/138 (38%), Positives = 76/138 (55%), Gaps = 1/138 (0%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PN+I +V + +V+E SGGELF+RI R+SE EA QQ+ SG++ H Sbjct: 102 PNVIHLHDVYEDANGVHLVLELCSGGELFDRIVAQDRYSESEAAEVVQQIASGLAALHKS 161 Query: 187 QVCHRDLKLENTL-LDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEY 363 + HRDLK EN L L+ LKI DFG S + G+ Y++PE L +++ Sbjct: 162 TIIHRDLKPENCLFLNQEKRSTLKIMDFGLSSVEDFTDPIVALFGSIDYVSPEALSQRQV 221 Query: 364 DGKIADVWSRGVTLYVML 417 +D+WS GV LY++L Sbjct: 222 -SSASDMWSLGVILYILL 238
>KCC2D_HUMAN (Q13557) Calcium/calmodulin-dependent protein kinase type II delta| chain (EC 2.7.11.17) (CaM-kinase II delta chain) (CaM kinase II delta subunit) (CaMK-II delta subunit) Length = 499 Score = 91.7 bits (226), Expect = 6e-19 Identities = 56/139 (40%), Positives = 76/139 (54%), Gaps = 2/139 (1%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PNI+R + I +V + +GGELFE I +SE +A QQ+L V++CH Sbjct: 71 PNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLN 130 Query: 187 QVCHRDLKLENTLL-DGSTAPRLKICDFGYSKSSVLHSQP-KSTVGTPAYIAPEVLLKKE 360 + HRDLK EN LL S +K+ DFG + Q GTP Y++PEVL K Sbjct: 131 GIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDP 190 Query: 361 YDGKIADVWSRGVTLYVML 417 Y GK D+W+ GV LY++L Sbjct: 191 Y-GKPVDMWACGVILYILL 208
>SCK2_SCHPO (Q10364) Serine/threonine-protein kinase sck2 (EC 2.7.11.1)| Length = 646 Score = 91.7 bits (226), Expect = 6e-19 Identities = 51/137 (37%), Positives = 78/137 (56%), Gaps = 1/137 (0%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 P I+ + TP L +V +Y +GGELF + + RF E+ A+F+ +LL + H Sbjct: 327 PFIVALRFSFQTPKDLYLVTDYMAGGELFWHLQKSVRFPEERAKFYIAELLLALQALHKR 386 Query: 187 QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSV-LHSQPKSTVGTPAYIAPEVLLKKEY 363 + +RDLK EN LLD + +CDFG SK+++ + + ++ GT Y+APEV+L + Sbjct: 387 GIVYRDLKPENILLD--VQGHIALCDFGLSKANLSVGTTTRTFCGTTDYLAPEVILDEAG 444 Query: 364 DGKIADVWSRGVTLYVM 414 + D WS GV LY M Sbjct: 445 YDMMVDFWSLGVLLYEM 461
>KCC2D_RAT (P15791) Calcium/calmodulin-dependent protein kinase type II delta| chain (EC 2.7.11.17) (CaM-kinase II delta chain) (CaM kinase II delta subunit) (CaMK-II delta subunit) Length = 533 Score = 91.7 bits (226), Expect = 6e-19 Identities = 56/139 (40%), Positives = 76/139 (54%), Gaps = 2/139 (1%) Frame = +1 Query: 7 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLLSGVSYCHSM 186 PNI+R + I +V + +GGELFE I +SE +A QQ+L V++CH Sbjct: 71 PNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLN 130 Query: 187 QVCHRDLKLENTLL-DGSTAPRLKICDFGYSKSSVLHSQP-KSTVGTPAYIAPEVLLKKE 360 + HRDLK EN LL S +K+ DFG + Q GTP Y++PEVL K Sbjct: 131 GIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDP 190 Query: 361 YDGKIADVWSRGVTLYVML 417 Y GK D+W+ GV LY++L Sbjct: 191 Y-GKPVDMWACGVILYILL 208 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 58,682,275 Number of Sequences: 219361 Number of extensions: 1222652 Number of successful extensions: 7502 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 5470 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5770 length of database: 80,573,946 effective HSP length: 100 effective length of database: 58,637,846 effective search space used: 2228238148 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
