ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | basd20k05 |
|---|---|
| Clone Library Name | barley_pub |
>ALDR_HORVU (P23901) Aldose reductase (EC 1.1.1.21) (AR) (Aldehyde reductase)| Length = 320 Score = 154 bits (389), Expect = 1e-37 Identities = 74/157 (47%), Positives = 105/157 (66%), Gaps = 2/157 (1%) Frame = +3 Query: 6 IGVALNKVLDEGVVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IH 185 +G L ++ G+ R+DLF+TSKIWC++LAPE V A++ TL DLQLDY+DL+ IH Sbjct: 66 VGKGLKAAMEAGI-DRKDLFVTSKIWCTNLAPERVRPALENTLKDLQLDYIDLYH---IH 121 Query: 186 WPFQIKKGSELSPE--NFVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADLLAVAR 359 WPF++K G+ + PE +E DM W+ ME L G + IGV N++ KL LL A+ Sbjct: 122 WPFRLKDGAHMPPEAGEVLEFDMEGVWKEMENLVKDGLVKDIGVCNYTVTKLNRLLRSAK 181 Query: 360 VPPAVDQVECHPGWQQAKLRAFCRTNGVHFSAYAPLG 470 +PPAV Q+E HPGW+ K+ C+ +G+H +AY+PLG Sbjct: 182 IPPAVCQMEMHPGWKNDKIFEACKKHGIHVTAYSPLG 218
>6DCS_SOYBN (P26690) NAD(P)H dependent 6'-deoxychalcone synthase (EC 2.3.1.170)| Length = 315 Score = 136 bits (343), Expect = 3e-32 Identities = 71/157 (45%), Positives = 100/157 (63%), Gaps = 3/157 (1%) Frame = +3 Query: 6 IGVALNKVLDEGVVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IH 185 +G AL + + G+V R+DLF+TSK+W ++ P V A+ +L LQL+YLDL+L IH Sbjct: 65 LGEALKEAIHLGLVSRQDLFVTSKLWVTENHPHLVLPALRKSLKTLQLEYLDLYL---IH 121 Query: 186 WPFQIKKGSELSP---ENFVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADLLAVA 356 WP + G P E+ + D+ W +ME+ G +AIGVSNFS KKL +LL+VA Sbjct: 122 WPLSSQPGKFSFPIEVEDLLPFDVKGVWESMEECQKLGLTKAIGVSNFSVKKLQNLLSVA 181 Query: 357 RVPPAVDQVECHPGWQQAKLRAFCRTNGVHFSAYAPL 467 + P VDQVE + WQQ KLR FC+ NG+ +A++PL Sbjct: 182 TIRPVVDQVEMNLAWQQKKLREFCKENGIIVTAFSPL 218
>AK1A1_PIG (P50578) Alcohol dehydrogenase [NADP+] (EC 1.1.1.2) (Aldehyde| reductase) (Aldo-keto reductase family 1 member A1) Length = 324 Score = 135 bits (339), Expect = 8e-32 Identities = 73/162 (45%), Positives = 103/162 (63%), Gaps = 7/162 (4%) Frame = +3 Query: 6 IGVALNKVLDEG-VVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*I 182 IG AL + + G V RE+LF+TSK+W + PEDV A+ TL DLQL+YLDL+L+ Sbjct: 55 IGEALTETVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLM--- 111 Query: 183 HWPFQIKKGSELSPEN------FVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADL 344 HWP+ ++G P+N + TW+A+E L G RA+G+SNFS++++ D+ Sbjct: 112 HWPYAFERGDNPFPKNADGTIRYDATHYKDTWKALEALVAKGLVRALGLSNFSSRQIDDV 171 Query: 345 LAVARVPPAVDQVECHPGWQQAKLRAFCRTNGVHFSAYAPLG 470 L+VA V PAV QVECHP Q +L A C+ G+ +AY+PLG Sbjct: 172 LSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLG 213
>AK1A1_RAT (P51635) Alcohol dehydrogenase [NADP+] (EC 1.1.1.2) (Aldehyde| reductase) (Aldo-keto reductase family 1 member A1) (3-DG-reducing enzyme) Length = 324 Score = 134 bits (338), Expect = 1e-31 Identities = 72/162 (44%), Positives = 104/162 (64%), Gaps = 7/162 (4%) Frame = +3 Query: 6 IGVALNKVLDEG-VVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*I 182 IG AL + + G V RE+LF+TSK+W + PEDV A+ TL DLQL+YLDL+L+ Sbjct: 55 IGEALKESVGAGKAVPREELFVTSKLWNTKHHPEDVEPAVRKTLADLQLEYLDLYLM--- 111 Query: 183 HWPFQIKKGSELSPEN------FVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADL 344 HWP+ ++G P+N + +TW+A+E L G +A+G+SNFS++++ D+ Sbjct: 112 HWPYAFERGDNPFPKNADGTVKYDSTHYKETWKALEALVAKGLVKALGLSNFSSRQIDDV 171 Query: 345 LAVARVPPAVDQVECHPGWQQAKLRAFCRTNGVHFSAYAPLG 470 L+VA V PAV QVECHP Q +L A C+ G+ +AY+PLG Sbjct: 172 LSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLG 213
>AK1A1_CRIGR (O70473) Alcohol dehydrogenase [NADP+] (EC 1.1.1.2) (Aldehyde| reductase) (Aldo-keto reductase family 1 member A1) (Fragment) Length = 228 Score = 134 bits (336), Expect = 2e-31 Identities = 71/162 (43%), Positives = 105/162 (64%), Gaps = 7/162 (4%) Frame = +3 Query: 6 IGVALNKVLDEG-VVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*I 182 IG AL + + G V RE+LF+TSK+W + PEDV +A+ TL DLQL+YLDL+L+ Sbjct: 41 IGEALKENVGPGKAVPREELFVTSKLWNTKHHPEDVEAALRKTLADLQLEYLDLYLM--- 97 Query: 183 HWPFQIKKGSELSPEN------FVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADL 344 HWP+ ++G P+N + +TW+A+E L G +A+G+SNF+++++ D+ Sbjct: 98 HWPYAFERGDNPFPKNDDGTIRYDSTHYKETWKALEALVAKGLVKALGLSNFNSRQIDDI 157 Query: 345 LAVARVPPAVDQVECHPGWQQAKLRAFCRTNGVHFSAYAPLG 470 L+VA V PAV QVECHP Q +L A C+ G+ +AY+PLG Sbjct: 158 LSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLG 199
>ALDR_RABIT (P15122) Aldose reductase (EC 1.1.1.21) (AR) (Aldehyde reductase)| Length = 315 Score = 134 bits (336), Expect = 2e-31 Identities = 75/163 (46%), Positives = 98/163 (60%), Gaps = 8/163 (4%) Frame = +3 Query: 6 IGVALNKVLDEGVVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IH 185 +GVAL + L E VVKRE+LFI SK+WC+ V A TLNDL+LDYLDL+L IH Sbjct: 54 VGVALQEKLKEQVVKREELFIVSKLWCTSHDKSLVKGACQKTLNDLKLDYLDLYL---IH 110 Query: 186 WPFQIKKGSELSPENFV------ELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADLL 347 WP K GSE P + + D TW AME L D G ++IGVSNF+ ++ +L Sbjct: 111 WPTGFKHGSEYFPLDAAGNVIPSDTDFLDTWEAMEGLVDEGLVKSIGVSNFNHLQIERIL 170 Query: 348 --AVARVPPAVDQVECHPGWQQAKLRAFCRTNGVHFSAYAPLG 470 + PAV+Q+ECHP Q KL +C + G+ +AY+PLG Sbjct: 171 NKPGLKYKPAVNQIECHPYLTQEKLIQYCHSKGIVVTAYSPLG 213
>AK1A1_MOUSE (Q9JII6) Alcohol dehydrogenase [NADP+] (EC 1.1.1.2) (Aldehyde| reductase) (Aldo-keto reductase family 1 member A1) Length = 324 Score = 132 bits (333), Expect = 4e-31 Identities = 71/162 (43%), Positives = 103/162 (63%), Gaps = 7/162 (4%) Frame = +3 Query: 6 IGVALNKVLDEG-VVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*I 182 IG AL + + G V RE+LF+TSK+W + PEDV A+ TL DLQL+YLDL+L+ Sbjct: 55 IGEALKESVGSGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLM--- 111 Query: 183 HWPFQIKKGSELSPEN------FVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADL 344 HWP+ ++G P+N + +TW+A+E L G +A+G+SNF+++++ D+ Sbjct: 112 HWPYAFERGDNPFPKNADGTVRYDSTHYKETWKALEVLVAKGLVKALGLSNFNSRQIDDV 171 Query: 345 LAVARVPPAVDQVECHPGWQQAKLRAFCRTNGVHFSAYAPLG 470 L+VA V PAV QVECHP Q +L A C G+ +AY+PLG Sbjct: 172 LSVASVRPAVLQVECHPYLAQNELIAHCHARGLEVTAYSPLG 213
>AK1A1_HUMAN (P14550) Alcohol dehydrogenase [NADP+] (EC 1.1.1.2) (Aldehyde| reductase) (Aldo-keto reductase family 1 member A1) Length = 324 Score = 132 bits (333), Expect = 4e-31 Identities = 71/162 (43%), Positives = 104/162 (64%), Gaps = 7/162 (4%) Frame = +3 Query: 6 IGVALNKVLDEG-VVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*I 182 IG AL + + G V RE+LF+TSK+W + PEDV A+ TL DLQL+YLDL+L+ Sbjct: 55 IGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLM--- 111 Query: 183 HWPFQIKKGSELSPEN------FVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADL 344 HWP+ ++G P+N + +TW+A+E L G +A+G+SNF+++++ D+ Sbjct: 112 HWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDI 171 Query: 345 LAVARVPPAVDQVECHPGWQQAKLRAFCRTNGVHFSAYAPLG 470 L+VA V PAV QVECHP Q +L A C+ G+ +AY+PLG Sbjct: 172 LSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLG 213
>AK1C1_MACFU (Q95JH6) Aldo-keto reductase family 1 member C1 homolog (EC| 1.-.-.-) (20-alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.149) (20-alpha-HSD) (Dihydrodiol dehydrogenase 1) (DD-1) (DD1) Length = 323 Score = 132 bits (332), Expect = 5e-31 Identities = 70/163 (42%), Positives = 103/163 (63%), Gaps = 8/163 (4%) Frame = +3 Query: 6 IGVALNKVLDEGVVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IH 185 +G+A+ + +G VKRED+F TSK+WC+ PE V A++ +L +LQLDY+DL+L IH Sbjct: 61 VGLAIRSKIADGTVKREDIFYTSKLWCNSHRPEFVRPALERSLKNLQLDYVDLYL---IH 117 Query: 186 WPFQIKKGSELSPEN------FVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADLL 347 +P +K G EL P++ F +D+ TW AMEK D+G A++IGVSNF+ ++L +L Sbjct: 118 FPVSLKPGEELIPKDENGKLLFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNRRQLEMIL 177 Query: 348 --AVARVPPAVDQVECHPGWQQAKLRAFCRTNGVHFSAYAPLG 470 + P +QVECHP Q KL FC++ + AY+ LG Sbjct: 178 NKPGLKYKPVCNQVECHPYLNQRKLLDFCKSKDIVLVAYSALG 220
>ALDR_BOVIN (P16116) Aldose reductase (EC 1.1.1.21) (AR) (Aldehyde reductase)| (20-alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.149) (20-alpha-HSD) Length = 315 Score = 132 bits (331), Expect = 7e-31 Identities = 75/163 (46%), Positives = 99/163 (60%), Gaps = 8/163 (4%) Frame = +3 Query: 6 IGVALNKVLDEGVVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IH 185 +G+AL L E VVKREDLFI SK+WC+ + V A TL+DL+LDYLDL+L IH Sbjct: 54 VGLALQAKLQEQVVKREDLFIVSKLWCTYHDKDLVKGACQKTLSDLKLDYLDLYL---IH 110 Query: 186 WPFQIKKGSELSP----ENFV--ELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADLL 347 WP K G + P N + E D TW AME+L D G +AIGVSNF+ ++ +L Sbjct: 111 WPTGFKPGKDFFPLDEDGNVIPSEKDFVDTWTAMEELVDEGLVKAIGVSNFNHLQVEKIL 170 Query: 348 --AVARVPPAVDQVECHPGWQQAKLRAFCRTNGVHFSAYAPLG 470 + PAV+Q+ECHP Q KL +C + G+ +AY+PLG Sbjct: 171 NKPGLKYKPAVNQIECHPYLTQEKLIQYCNSKGIVVTAYSPLG 213
>NADO1_ORYSA (Q7G764) Probable NAD(P)H-dependent oxidoreductase 1 (EC 1.1.1.-)| Length = 321 Score = 131 bits (330), Expect = 9e-31 Identities = 75/160 (46%), Positives = 95/160 (59%), Gaps = 5/160 (3%) Frame = +3 Query: 6 IGVALNKVLDEGVV-KREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*I 182 +G A+ + + G++ R D+F+TSKIWCSDL V A TL +L +DY+DL LV Sbjct: 61 VGEAVAEAVRRGLIASRADVFVTSKIWCSDLHAGRVVPAARETLRNLGMDYVDLLLV--- 117 Query: 183 HWPFQIKKGSELSPEN----FVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADLLA 350 HWP + G+ P DM WR ME+ + G ARAIGVSNFS KKL LL+ Sbjct: 118 HWPVSLTPGNYDFPFPKEVILPSFDMEGVWRGMEECHRLGLARAIGVSNFSAKKLEQLLS 177 Query: 351 VARVPPAVDQVECHPGWQQAKLRAFCRTNGVHFSAYAPLG 470 +A V PAV+QVE +P WQQ LR CR GV Y+PLG Sbjct: 178 LAAVRPAVNQVEVNPMWQQRTLREVCRREGVQLCGYSPLG 217
>ALDR_RAT (P07943) Aldose reductase (EC 1.1.1.21) (AR) (Aldehyde reductase)| Length = 315 Score = 131 bits (330), Expect = 9e-31 Identities = 75/163 (46%), Positives = 98/163 (60%), Gaps = 8/163 (4%) Frame = +3 Query: 6 IGVALNKVLDEGVVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IH 185 +GVAL + L E VVKR+DLFI SK+WC+ V A TL+DLQLDYLDL+L IH Sbjct: 54 VGVALQEKLKEQVVKRQDLFIVSKLWCTFHDQSMVKGACQKTLSDLQLDYLDLYL---IH 110 Query: 186 WPFQIKKGSELSP----ENFV--ELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADLL 347 WP K G + P N + + D TW AME+L D G +AIGVSNF+ ++ +L Sbjct: 111 WPTGFKPGPDYFPLDASGNVIPSDTDFVDTWTAMEQLVDEGLVKAIGVSNFNPLQIERIL 170 Query: 348 --AVARVPPAVDQVECHPGWQQAKLRAFCRTNGVHFSAYAPLG 470 + PAV+Q+ECHP Q KL +C G+ +AY+PLG Sbjct: 171 NKPGLKYKPAVNQIECHPYLTQEKLIEYCHCKGIVVTAYSPLG 213
>AK1C1_PONPY (Q5REQ0) Aldo-keto reductase family 1 member C1 homolog (EC| 1.-.-.-) (20-alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.149) (20-alpha-HSD) Length = 323 Score = 131 bits (330), Expect = 9e-31 Identities = 69/163 (42%), Positives = 104/163 (63%), Gaps = 8/163 (4%) Frame = +3 Query: 6 IGVALNKVLDEGVVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IH 185 +G+A+ + +G VKRED+F TSK+WC+ PE V A++ +L +LQLDY+DL+LV H Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLV---H 117 Query: 186 WPFQIKKGSELSPEN------FVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADLL 347 +P +K G E+ P++ F +D+ TW AMEK D+G A++IGVSNF+ ++L +L Sbjct: 118 FPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNRRQLEMIL 177 Query: 348 --AVARVPPAVDQVECHPGWQQAKLRAFCRTNGVHFSAYAPLG 470 + P +QVECHP + Q KL FC++ + AY+ LG Sbjct: 178 NKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALG 220
>ALDR_MOUSE (P45376) Aldose reductase (EC 1.1.1.21) (AR) (Aldehyde reductase)| Length = 315 Score = 131 bits (329), Expect = 1e-30 Identities = 74/163 (45%), Positives = 98/163 (60%), Gaps = 8/163 (4%) Frame = +3 Query: 6 IGVALNKVLDEGVVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IH 185 +GVAL + L E VVKR+DLFI SK+WC+ V A TL+DLQLDYLDL+L IH Sbjct: 54 VGVALQEKLKEQVVKRQDLFIVSKLWCTFHDKSMVKGAFQKTLSDLQLDYLDLYL---IH 110 Query: 186 WPFQIKKGSELSP----ENFV--ELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADLL 347 WP K G + P N + + D TW AME+L D G + IGVSNF+ ++ +L Sbjct: 111 WPTGFKPGPDYFPLDASGNVIPSDTDFVDTWTAMEQLVDEGLVKTIGVSNFNPLQIERIL 170 Query: 348 --AVARVPPAVDQVECHPGWQQAKLRAFCRTNGVHFSAYAPLG 470 + PAV+Q+ECHP Q KL +C + G+ +AY+PLG Sbjct: 171 NKPGLKYKPAVNQIECHPYLTQEKLIEYCHSKGIVVTAYSPLG 213
>ALDR_PIG (P80276) Aldose reductase (EC 1.1.1.21) (AR) (Aldehyde reductase)| Length = 315 Score = 130 bits (328), Expect = 1e-30 Identities = 75/163 (46%), Positives = 99/163 (60%), Gaps = 8/163 (4%) Frame = +3 Query: 6 IGVALNKVLDEGVVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IH 185 +G+ L + L VVKREDLFI SK+WC+D V A TTL DL+LDYLDL+L IH Sbjct: 54 VGLGLQEKLQGQVVKREDLFIVSKLWCTDHEKNLVKGACQTTLRDLKLDYLDLYL---IH 110 Query: 186 WPFQIKKGSELSP----ENFV--ELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADLL 347 WP K G + P N V E D +TW AME+L D G +AIGVSNF+ ++ +L Sbjct: 111 WPTGFKPGKDPFPLDGDGNVVPDESDFVETWEAMEELVDEGLVKAIGVSNFNHLQVEKIL 170 Query: 348 --AVARVPPAVDQVECHPGWQQAKLRAFCRTNGVHFSAYAPLG 470 + PAV+Q+E HP Q KL +C++ G+ +AY+PLG Sbjct: 171 NKPGLKYKPAVNQIEVHPYLTQEKLIEYCKSKGIVVTAYSPLG 213
>PGFS2_BOVIN (P52897) Prostaglandin-F synthase 2 (EC 1.1.1.188) (PGF synthase 2)| (PGF 2) (Prostaglandin-D2 11 reductase 2) (PGFSII) Length = 323 Score = 130 bits (328), Expect = 1e-30 Identities = 68/163 (41%), Positives = 103/163 (63%), Gaps = 8/163 (4%) Frame = +3 Query: 6 IGVALNKVLDEGVVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IH 185 +G A+ + +G VKRED+F TSK+WC+ L PE V A++ +L +LQLDY+DL++ IH Sbjct: 61 VGQAIRSKIADGTVKREDIFYTSKLWCNSLQPELVRPALEKSLQNLQLDYVDLYI---IH 117 Query: 186 WPFQIKKGSELSPEN------FVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADLL 347 P +K G++ P++ F +D+ TW A+EK D+G ++IGVSNF+ K+L +L Sbjct: 118 SPVSLKPGNKFVPKDESGKLIFDSVDLCHTWEALEKCKDAGLTKSIGVSNFNHKQLEKIL 177 Query: 348 --AVARVPPAVDQVECHPGWQQAKLRAFCRTNGVHFSAYAPLG 470 + P +QVECHP Q+KL FC+++ + AYA LG Sbjct: 178 NKPGLKYKPVCNQVECHPYLNQSKLLEFCKSHDIVLVAYAALG 220
>PGFS1_BOVIN (P05980) Prostaglandin-F synthase 1 (EC 1.1.1.188) (PGF synthase 1)| (PGF 1) (Prostaglandin-D2 11 reductase 1) (PGFSI) Length = 323 Score = 130 bits (328), Expect = 1e-30 Identities = 68/163 (41%), Positives = 103/163 (63%), Gaps = 8/163 (4%) Frame = +3 Query: 6 IGVALNKVLDEGVVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IH 185 +G A+ + +G VKRED+F TSK+WC+ L PE V A++ +L +LQLDY+DL++ IH Sbjct: 61 VGQAIRSKIADGTVKREDIFYTSKLWCNSLQPELVRPALEKSLQNLQLDYVDLYI---IH 117 Query: 186 WPFQIKKGSELSPEN------FVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADLL 347 P +K G++ P++ F +D+ TW A+EK D+G ++IGVSNF+ K+L +L Sbjct: 118 SPVSLKPGNKFVPKDESGKLIFDSVDLCHTWEALEKCKDAGLTKSIGVSNFNHKQLEKIL 177 Query: 348 --AVARVPPAVDQVECHPGWQQAKLRAFCRTNGVHFSAYAPLG 470 + P +QVECHP Q+KL FC+++ + AYA LG Sbjct: 178 NKPGLKYKPVCNQVECHPYLNQSKLLEFCKSHDIVLVAYAALG 220
>AK1C1_MACFA (Q95JH7) Aldo-keto reductase family 1 member C1 homolog (EC| 1.-.-.-) (20-alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.149) (20-alpha-HSD) (Dihydrodiol dehydrogenase 1) (DD-1) (DD1) Length = 323 Score = 130 bits (328), Expect = 1e-30 Identities = 69/163 (42%), Positives = 103/163 (63%), Gaps = 8/163 (4%) Frame = +3 Query: 6 IGVALNKVLDEGVVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IH 185 +G+A+ + +G VKRED+F TSK+WC+ PE V A++ +L +LQLDY+DL+L IH Sbjct: 61 VGLAIRSKIADGTVKREDIFYTSKLWCNSHRPEFVRPALERSLKNLQLDYVDLYL---IH 117 Query: 186 WPFQIKKGSELSPEN------FVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADLL 347 +P +K G EL P++ F +D+ TW AMEK D+G A++IGVSNF+ ++L +L Sbjct: 118 FPVSLKPGEELIPKDENGKLLFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNRRQLEMIL 177 Query: 348 --AVARVPPAVDQVECHPGWQQAKLRAFCRTNGVHFSAYAPLG 470 + P +QVECHP Q KL FC++ + A++ LG Sbjct: 178 NKPGLKYKPVCNQVECHPYLNQRKLLDFCKSKDIVLVAFSALG 220
>YDG7_SCHPO (Q10494) Probable oxidoreductase C26F1.07 in chromosome I (EC| 1.-.-.-) Length = 321 Score = 130 bits (327), Expect = 2e-30 Identities = 66/158 (41%), Positives = 98/158 (62%), Gaps = 6/158 (3%) Frame = +3 Query: 30 LDEGVVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IHWPFQIKKG 209 + E V R+D+++TSK+WC+ APE VP A++ TL DL+LDYLD +L IHWP K G Sbjct: 70 IKESGVPRKDIWVTSKLWCNAHAPEAVPKALEKTLKDLKLDYLDEYL---IHWPVSFKTG 126 Query: 210 SELSPEN------FVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADLLAVARVPPA 371 + P++ + + + +TW+AMEKL ++GK R IG+SNF+ L +L VA+V PA Sbjct: 127 EDKFPKDKDGNLIYEKNPIEETWKAMEKLLETGKVRHIGLSNFNDTNLERILKVAKVKPA 186 Query: 372 VDQVECHPGWQQAKLRAFCRTNGVHFSAYAPLGRMKVV 485 V Q+E HP Q + + G+H +AY+P G + Sbjct: 187 VHQMELHPFLPQTEFVEKHKKLGIHVTAYSPFGNQNTI 224
>DDBX_BOVIN (P52898) Dihydrodiol dehydrogenase 3 (EC 1.-.-.-) (Prostaglandin F| synthase) Length = 323 Score = 130 bits (327), Expect = 2e-30 Identities = 68/167 (40%), Positives = 105/167 (62%), Gaps = 8/167 (4%) Frame = +3 Query: 6 IGVALNKVLDEGVVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IH 185 +G A+ + +G VKRED+F TSK+W + L PE V A++ +LN+LQLDY+DL++ IH Sbjct: 61 VGQAIRSKIADGTVKREDIFYTSKLWSTSLRPELVRPALEKSLNNLQLDYVDLYI---IH 117 Query: 186 WPFQIKKGSELSPEN------FVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADLL 347 +P +K G L P + F +D+ +TW A+EK D+G ++IGVSNF+ K+L +L Sbjct: 118 FPVALKPGETLFPTDENGKPIFDSVDLCRTWEALEKCKDAGLTKSIGVSNFNHKQLEKIL 177 Query: 348 --AVARVPPAVDQVECHPGWQQAKLRAFCRTNGVHFSAYAPLGRMKV 482 + P +QVECHP + Q+KL FC+++ + AY LG ++ Sbjct: 178 NKPGLKYKPVCNQVECHPYFNQSKLLDFCKSHDIVLVAYGALGSQRL 224
>AK1C1_HUMAN (Q04828) Aldo-keto reductase family 1 member C1 (EC 1.1.1.-)| (20-alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.149) (20-alpha-HSD) (Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase) (EC 1.3.1.20) (High-affinity hepatic bile acid-binding protei Length = 323 Score = 130 bits (326), Expect = 3e-30 Identities = 68/163 (41%), Positives = 104/163 (63%), Gaps = 8/163 (4%) Frame = +3 Query: 6 IGVALNKVLDEGVVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IH 185 +G+A+ + +G VKRED+F TSK+WC+ PE V A++ +L +LQLDY+DL+L IH Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYL---IH 117 Query: 186 WPFQIKKGSELSPEN------FVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADLL 347 +P +K G E+ P++ F +D+ TW A+EK D+G A++IGVSNF+ ++L +L Sbjct: 118 FPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMIL 177 Query: 348 --AVARVPPAVDQVECHPGWQQAKLRAFCRTNGVHFSAYAPLG 470 + P +QVECHP + Q KL FC++ + AY+ LG Sbjct: 178 NKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALG 220
>NADO2_ORYSA (Q7G765) Probable NAD(P)H-dependent oxidoreductase 2 (EC 1.-.-.-)| Length = 322 Score = 129 bits (323), Expect = 6e-30 Identities = 73/147 (49%), Positives = 86/147 (58%), Gaps = 4/147 (2%) Frame = +3 Query: 42 VVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IHWPFQIKKGSELS 221 V R D+F+TSK+WCSDL V A TL +L +DY+DL LV HWP + GS Sbjct: 76 VASRADVFVTSKLWCSDLHAGRVVPAARETLRNLGMDYVDLLLV---HWPATVAPGSYDF 132 Query: 222 P----ENFVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADLLAVARVPPAVDQVEC 389 P E DM WR ME+ + G ARAIGVSNFS KKL LL+ A V PA +QVE Sbjct: 133 PFPKEEMAPAFDMEGVWRGMEECHRLGLARAIGVSNFSAKKLEQLLSFAVVRPAANQVEM 192 Query: 390 HPGWQQAKLRAFCRTNGVHFSAYAPLG 470 +P WQQ LR CR GV Y+PLG Sbjct: 193 NPMWQQRTLREVCRREGVQLCGYSPLG 219
>PE2R_RABIT (P80508) Prostaglandin-E(2) 9-reductase (EC 1.1.1.189)| (20-alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.149) (20-alpha-HSD) Length = 323 Score = 129 bits (323), Expect = 6e-30 Identities = 68/163 (41%), Positives = 103/163 (63%), Gaps = 8/163 (4%) Frame = +3 Query: 6 IGVALNKVLDEGVVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IH 185 +G+A+ + +G VKRED+F TSK+WC+ PE V +++ +L +LQLDY+DL++ IH Sbjct: 61 VGLAIRSKIADGTVKREDIFYTSKLWCTFHRPELVRPSLEDSLKNLQLDYVDLYI---IH 117 Query: 186 WPFQIKKGSELSPEN------FVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADLL 347 +P +K G E+ P + F +D+ TW AMEK D+G A++IGVSNF+ ++L +L Sbjct: 118 FPTALKPGVEIIPTDEHGKAIFDTVDICATWEAMEKCKDAGLAKSIGVSNFNRRQLEMIL 177 Query: 348 --AVARVPPAVDQVECHPGWQQAKLRAFCRTNGVHFSAYAPLG 470 + P +QVECHP Q KL FC++ G+ AY+ LG Sbjct: 178 NKPGLKYKPVCNQVECHPYLNQGKLLEFCKSKGIVLVAYSALG 220
>XYL1_PICST (P31867) NAD(P)H-dependent D-xylose reductase (EC 1.1.1.-) (XR)| Length = 318 Score = 128 bits (322), Expect = 7e-30 Identities = 75/172 (43%), Positives = 106/172 (61%), Gaps = 12/172 (6%) Frame = +3 Query: 6 IGVALNKVLDEGVVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IH 185 +G + K +DEG+VKREDLF+TSK+W + P++V A++ TL+DLQ+DY+DL L IH Sbjct: 54 VGAGVKKAIDEGIVKREDLFLTSKLWNNYHHPDNVEKALNRTLSDLQVDYVDLFL---IH 110 Query: 186 WP--FQIKKGSELSP--------ENFVELDMP--QTWRAMEKLYDSGKARAIGVSNFSTK 329 +P F+ E P +NF D+P +TW+A+EKL +GK R+IGVSNF Sbjct: 111 FPVTFKFVPLEEKYPPGFYCGKGDNFDYEDVPILETWKALEKLVKAGKIRSIGVSNFPGA 170 Query: 330 KLADLLAVARVPPAVDQVECHPGWQQAKLRAFCRTNGVHFSAYAPLGRMKVV 485 L DLL A + P+V QVE HP QQ +L F ++ G+ +AY+ G V Sbjct: 171 LLLDLLRGATIKPSVLQVEHHPYLQQPRLIEFAQSRGIAVTAYSSFGPQSFV 222
>ALDR_HUMAN (P15121) Aldose reductase (EC 1.1.1.21) (AR) (Aldehyde reductase)| Length = 315 Score = 128 bits (321), Expect = 1e-29 Identities = 74/163 (45%), Positives = 100/163 (61%), Gaps = 8/163 (4%) Frame = +3 Query: 6 IGVALNKVLDEGVVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IH 185 +GVA+ + L E VVKRE+LFI SK+WC+ V A TL+DL+LDYLDL+L IH Sbjct: 54 VGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYL---IH 110 Query: 186 WPFQIKKGSELSP----ENFVELD--MPQTWRAMEKLYDSGKARAIGVSNFSTKKLADLL 347 WP K G E P N V D + TW AME+L D G +AIG+SNF+ ++ +L Sbjct: 111 WPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMIL 170 Query: 348 --AVARVPPAVDQVECHPGWQQAKLRAFCRTNGVHFSAYAPLG 470 + PAV+Q+ECHP Q KL +C++ G+ +AY+PLG Sbjct: 171 NKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLG 213
>XYL1_PICGU (O94735) NADPH-dependent D-xylose reductase (EC 1.1.1.-) (XR)| Length = 317 Score = 126 bits (317), Expect = 3e-29 Identities = 70/172 (40%), Positives = 104/172 (60%), Gaps = 12/172 (6%) Frame = +3 Query: 6 IGVALNKVLDEGVVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IH 185 +G +N+ LDEG+V R++LF+ SK+W S P++V A+D TL+DL++DYLDL L IH Sbjct: 53 VGDGINRALDEGLVARDELFVVSKLWNSFHDPKNVEKALDKTLSDLKVDYLDLFL---IH 109 Query: 186 WP--FQIKKGSELSPENFV----------ELDMPQTWRAMEKLYDSGKARAIGVSNFSTK 329 +P F+ E P F ++ + TWRA+EKL + GK R+IG+SNFS Sbjct: 110 FPIAFKFVPFEEKYPPGFYCGDGDKFHYEDVPLIDTWRALEKLVEKGKIRSIGISNFSGA 169 Query: 330 KLADLLAVARVPPAVDQVECHPGWQQAKLRAFCRTNGVHFSAYAPLGRMKVV 485 + DLL A++ PAV Q+E HP QQ +L + ++ G+ +AY+ G V Sbjct: 170 LIQDLLRSAKIKPAVLQIEHHPYLQQPRLVEYVQSQGIAITAYSSFGPQSFV 221
>DHB5_MOUSE (P70694) Estradiol 17 beta-dehydrogenase 5 (EC 1.1.1.-)| (17-beta-HSD 5) Length = 323 Score = 126 bits (316), Expect = 4e-29 Identities = 67/163 (41%), Positives = 99/163 (60%), Gaps = 8/163 (4%) Frame = +3 Query: 6 IGVALNKVLDEGVVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IH 185 +G+A+ + +G VKRED+F TSK+WC+ PE V ++ +L LQLDY+DL+L IH Sbjct: 61 VGLAIRSKIADGTVKREDIFYTSKVWCTFHRPELVRVCLEQSLKQLQLDYVDLYL---IH 117 Query: 186 WPFQIKKGSELSPEN------FVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADLL 347 +P +K G P++ + +D+ TW AMEK D+G A++IGVSNF+ ++L +L Sbjct: 118 FPMAMKPGENYLPKDENGKLIYDAVDICDTWEAMEKCKDAGLAKSIGVSNFNRRQLEKIL 177 Query: 348 AV--ARVPPAVDQVECHPGWQQAKLRAFCRTNGVHFSAYAPLG 470 + P +QVECHP Q KL FCR+ + AY+ LG Sbjct: 178 KKPGLKYKPVCNQVECHPYLNQGKLLDFCRSKDIVLVAYSALG 220
>AK1C2_HUMAN (P52895) Aldo-keto reductase family 1 member C2 (EC 1.-.-.-)| (Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase) (EC 1.3.1.20) (Type III 3-alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.213) (3-alpha-HSD3) (Chlordecone reductase homolog HAKRD) ( Length = 323 Score = 126 bits (316), Expect = 4e-29 Identities = 68/163 (41%), Positives = 102/163 (62%), Gaps = 8/163 (4%) Frame = +3 Query: 6 IGVALNKVLDEGVVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IH 185 +G+A+ + +G VKRED+F TSK+W + PE V A++ +L +LQLDY+DL+L IH Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYL---IH 117 Query: 186 WPFQIKKGSELSPEN------FVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADLL 347 +P +K G E+ P++ F +D+ TW AMEK D+G A++IGVSNF+ + L +L Sbjct: 118 FPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMIL 177 Query: 348 --AVARVPPAVDQVECHPGWQQAKLRAFCRTNGVHFSAYAPLG 470 + P +QVECHP + Q KL FC++ + AY+ LG Sbjct: 178 NKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALG 220
>AKC1H_MOUSE (Q8K023) Aldo-keto reductase family 1 member C18 (EC 1.1.-.-)| (20-alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.149) (20-alpha-HSD) Length = 323 Score = 124 bits (312), Expect = 1e-28 Identities = 68/166 (40%), Positives = 102/166 (61%), Gaps = 8/166 (4%) Frame = +3 Query: 6 IGVALNKVLDEGVVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IH 185 IG A+ +++G VKRED+F TSK+W + PE V +++ +L L LDY+DL+L IH Sbjct: 61 IGQAILSKIEDGTVKREDIFYTSKLWSTSHRPELVRPSLENSLRKLNLDYVDLYL---IH 117 Query: 186 WPFQIKKGSELSPEN------FVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADLL 347 +P +K G+EL P++ F +D+ TW AMEK D+G A++IGVSNF+ ++L +L Sbjct: 118 FPVSLKPGNELLPKDEHGNLIFDTVDLCDTWEAMEKCKDAGLAKSIGVSNFNRRQLEMIL 177 Query: 348 --AVARVPPAVDQVECHPGWQQAKLRAFCRTNGVHFSAYAPLGRMK 479 + P +QVECH Q+KL A+C+ N + AY LG + Sbjct: 178 NKPGLKYKPVCNQVECHLYLNQSKLLAYCKMNDIVLVAYGALGTQR 223
>AK1C3_HUMAN (P42330) Aldo-keto reductase family 1 member C3 (EC 1.-.-.-)| (Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase) (EC 1.3.1.20) (3-alpha-hydroxysteroid dehydrogenase type 2) (EC 1.1.1.213) (3-alpha-HSD type 2) (3-alpha-HSD type II, brain) (Prost Length = 323 Score = 124 bits (311), Expect = 1e-28 Identities = 68/166 (40%), Positives = 102/166 (61%), Gaps = 8/166 (4%) Frame = +3 Query: 6 IGVALNKVLDEGVVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IH 185 +G+A+ + +G VKRED+F TSK+W + PE V A++ +L QLDY+DL+L IH Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYL---IH 117 Query: 186 WPFQIKKGSELSPEN------FVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADLL 347 P +K G ELSP + F +D+ TW AMEK D+G A++IGVSNF+ ++L +L Sbjct: 118 SPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMIL 177 Query: 348 --AVARVPPAVDQVECHPGWQQAKLRAFCRTNGVHFSAYAPLGRMK 479 + P +QVECHP + ++KL FC++ + AY+ LG + Sbjct: 178 NKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQR 223
>ALDX_SPOSA (P27800) Aldehyde reductase 1 (EC 1.1.1.2) (Aldehyde reductase I)| (Alcohol dehydrogenase [NADP+]) (ALR) Length = 322 Score = 123 bits (309), Expect = 2e-28 Identities = 68/164 (41%), Positives = 95/164 (57%), Gaps = 11/164 (6%) Frame = +3 Query: 30 LDEGVVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IHWPFQIKKG 209 + E VKREDLFITSK+W + PE V A+D TL +L L+YLDL+L IHWP Sbjct: 58 IKEAGVKREDLFITSKLWNNSHRPEQVEPALDDTLKELGLEYLDLYL---IHWPVAFPPE 114 Query: 210 SELSPENF-----------VELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADLLAVA 356 +++ F +E+ + TW+AM KL D+GK +AIGVSNF K + ++ Sbjct: 115 GDITQNLFPKANDKEVKLDLEVSLVDTWKAMVKLLDTGKVKAIGVSNFDAKMVDAIIEAT 174 Query: 357 RVPPAVDQVECHPGWQQAKLRAFCRTNGVHFSAYAPLGRMKVVA 488 V P+V+Q+E HP Q +L A + +H +AY+PLG V A Sbjct: 175 GVTPSVNQIERHPLLLQPELIAHHKAKNIHITAYSPLGNNTVGA 218
>AK1C4_HUMAN (P17516) Aldo-keto reductase family 1 member C4 (EC 1.1.1.-)| (Chlordecone reductase) (EC 1.1.1.225) (CDR) (3-alpha-hydroxysteroid dehydrogenase type I) (EC 1.1.1.50) (3-alpha-HSD1) (Dihydrodiol dehydrogenase 4) (DD4) (HAKRA) Length = 323 Score = 123 bits (309), Expect = 2e-28 Identities = 64/166 (38%), Positives = 102/166 (61%), Gaps = 8/166 (4%) Frame = +3 Query: 6 IGVALNKVLDEGVVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IH 185 +G+A+ + +G VKRED+F TSK+WC+ P+ V A++++L LQLDY+DL+L +H Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYL---LH 117 Query: 186 WPFQIKKGSELSPEN------FVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADLL 347 +P +K G P++ F +D+ TW MEK D+G A++IGVSNF+ ++L +L Sbjct: 118 FPMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMIL 177 Query: 348 --AVARVPPAVDQVECHPGWQQAKLRAFCRTNGVHFSAYAPLGRMK 479 + P +QVECHP Q+KL FC++ + A++ LG + Sbjct: 178 NKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQR 223
>AK1C3_PONPY (Q5R7C9) Aldo-keto reductase family 1 member C3 homolog (EC| 1.-.-.-) (Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase) (EC 1.3.1.20) (3-alpha-hydroxysteroid dehydrogenase type 2) (EC 1.1.1.213) (3-alpha-HSD type 2) (Prostaglandin F synthase) Length = 323 Score = 122 bits (307), Expect = 4e-28 Identities = 67/166 (40%), Positives = 102/166 (61%), Gaps = 8/166 (4%) Frame = +3 Query: 6 IGVALNKVLDEGVVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IH 185 +G+A+ + +G VKRED+F TSK+W + PE V A++ +L QLDY+DL+L IH Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYL---IH 117 Query: 186 WPFQIKKGSELSPEN------FVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADLL 347 P +K G ELSP + F +D+ TW AME+ D+G A++IGVSNF+ ++L +L Sbjct: 118 SPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEECKDAGLAKSIGVSNFNRRQLEMIL 177 Query: 348 --AVARVPPAVDQVECHPGWQQAKLRAFCRTNGVHFSAYAPLGRMK 479 + P +QVECHP + ++KL FC++ + AY+ LG + Sbjct: 178 NKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQR 223
>AKC1H_RAT (P51652) Aldo-keto reductase family 1 member C18 (EC 1.1.-.-)| (20-alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.149) (20-alpha-HSD) (HSD1) Length = 323 Score = 122 bits (306), Expect = 5e-28 Identities = 67/166 (40%), Positives = 100/166 (60%), Gaps = 8/166 (4%) Frame = +3 Query: 6 IGVALNKVLDEGVVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IH 185 IG A+ +++G VKRED+F TSK+W + PE V +++ +L L LDY+DL+L IH Sbjct: 61 IGQAIVSKIEDGTVKREDIFYTSKLWSTSHRPELVRPSLENSLRKLNLDYVDLYL---IH 117 Query: 186 WPFQIKKGSELSPEN------FVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADLL 347 +P +K G EL P++ +D+ TW AMEK D+G A++IGVSNF+ ++L +L Sbjct: 118 FPVSLKPGDELLPQDEHGNLILDTVDLCDTWEAMEKCKDAGLAKSIGVSNFNRRQLEKIL 177 Query: 348 AVARVP--PAVDQVECHPGWQQAKLRAFCRTNGVHFSAYAPLGRMK 479 + P +QVECH Q+KL A+C+ N + AY LG + Sbjct: 178 NKPGLKHRPVCNQVECHLYLNQSKLLAYCKMNDIVLVAYGALGTQR 223
>AK1C4_MACFU (Q95JH4) Aldo-keto reductase family 1 member C4 (EC 1.1.1.-)| (Chlordecone reductase) (EC 1.1.1.225) (CDR) (3-alpha-hydroxysteroid dehydrogenase type I) (EC 1.1.1.50) (3-alpha-HSD1) (Dihydrodiol dehydrogenase 4) (DD4) (DD-4) Length = 323 Score = 122 bits (306), Expect = 5e-28 Identities = 65/166 (39%), Positives = 102/166 (61%), Gaps = 8/166 (4%) Frame = +3 Query: 6 IGVALNKVLDEGVVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IH 185 +G+A+ + +G VKRED+F TSK+WC+ P+ V A++++L LQLDY+DL+L IH Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWCTFFRPQLVQPALESSLKKLQLDYVDLYL---IH 117 Query: 186 WPFQIKKGSELSPEN------FVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADLL 347 +P +K G P++ F +D+ W AMEK D+G A++IGVSNF+ ++L +L Sbjct: 118 FPMALKPGETPLPKDENGKVMFDTVDLCAIWEAMEKCKDAGLAKSIGVSNFNRRQLEMIL 177 Query: 348 --AVARVPPAVDQVECHPGWQQAKLRAFCRTNGVHFSAYAPLGRMK 479 + P +QVECHP Q+KL FC++ + A++ LG + Sbjct: 178 NNPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQR 223
>AK1C4_MACFA (Q95JH5) Aldo-keto reductase family 1 member C4 (EC 1.1.1.-)| (Chlordecone reductase) (EC 1.1.1.225) (CDR) (3-alpha-hydroxysteroid dehydrogenase type I) (EC 1.1.1.50) (3-alpha-HSD1) (Dihydrodiol dehydrogenase 4) (DD4) (DD-4) Length = 323 Score = 122 bits (306), Expect = 5e-28 Identities = 65/166 (39%), Positives = 102/166 (61%), Gaps = 8/166 (4%) Frame = +3 Query: 6 IGVALNKVLDEGVVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IH 185 +G+A+ + +G VKRED+F TSK+WC+ P+ V A++++L LQLDY+DL+L IH Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWCTFFRPQLVQPALESSLKKLQLDYVDLYL---IH 117 Query: 186 WPFQIKKGSELSPEN------FVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADLL 347 +P +K G P++ F +D+ W AMEK D+G A++IGVSNF+ ++L +L Sbjct: 118 FPMALKPGETPLPKDENGKVMFDTVDLCAIWEAMEKCKDAGLAKSIGVSNFNRRQLEMIL 177 Query: 348 --AVARVPPAVDQVECHPGWQQAKLRAFCRTNGVHFSAYAPLGRMK 479 + P +QVECHP Q+KL FC++ + A++ LG + Sbjct: 178 NNPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQR 223
>XYL1_CANTE (O74237) NAD(P)H-dependent D-xylose reductase (EC 1.1.1.-) (XR)| Length = 322 Score = 122 bits (306), Expect = 5e-28 Identities = 74/172 (43%), Positives = 105/172 (61%), Gaps = 12/172 (6%) Frame = +3 Query: 6 IGVALNKVLDEGVVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IH 185 +G + + +DEG+VKRE++F+TSK+W + P++V +A++ TL DL++DY+DL L IH Sbjct: 58 VGDGVKRAIDEGLVKREEIFLTSKLWNNYHDPKNVETALNKTLADLKVDYVDLFL---IH 114 Query: 186 WP--FQIKKGSELSP--------ENFVELDMP--QTWRAMEKLYDSGKARAIGVSNFSTK 329 +P F+ E P NFV D+P +TW+A+EKL +GK ++IGVSNF Sbjct: 115 FPIAFKFVPIEEKYPPGFYCGDGNNFVYEDVPILETWKALEKLVAAGKIKSIGVSNFPGA 174 Query: 330 KLADLLAVARVPPAVDQVECHPGWQQAKLRAFCRTNGVHFSAYAPLGRMKVV 485 L DLL A + PAV QVE HP QQ KL F + GV +AY+ G V Sbjct: 175 LLLDLLRGATIKPAVLQVEHHPYLQQPKLIEFAQKAGVTITAYSSFGPQSFV 226
>XYL1_CANSH (Q9P430) NAD(P)H-dependent D-xylose reductase (EC 1.1.1.-) (XR)| Length = 323 Score = 120 bits (301), Expect = 2e-27 Identities = 71/172 (41%), Positives = 104/172 (60%), Gaps = 12/172 (6%) Frame = +3 Query: 6 IGVALNKVLDEGVVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IH 185 +G + + +DEG+V RE++F+TSK+W + P++V +A++ TL DL++DY+DL L IH Sbjct: 59 VGEGVKRAIDEGIVTREEIFLTSKLWNNYHDPKNVETALNKTLKDLKVDYVDLFL---IH 115 Query: 186 WP--FQIKKGSELSP--------ENFVELDMP--QTWRAMEKLYDSGKARAIGVSNFSTK 329 +P F+ E P +NFV D+P +TW+A+EKL +GK R+IGVSNF Sbjct: 116 FPIAFKFVPIEEKYPPGFYCGDGDNFVYEDVPILETWKALEKLVKAGKIRSIGVSNFPGA 175 Query: 330 KLADLLAVARVPPAVDQVECHPGWQQAKLRAFCRTNGVHFSAYAPLGRMKVV 485 L DL A + PAV QVE HP QQ KL + + G+ +AY+ G V Sbjct: 176 LLLDLFRGATIKPAVLQVEHHPYLQQPKLIEYAQKVGITVTAYSSFGPQSFV 227
>XYL2_CANTR (P87039) NADPH-dependent D-xylose reductase II,III (EC 1.1.1.-)| (XR) Length = 324 Score = 119 bits (298), Expect = 4e-27 Identities = 68/167 (40%), Positives = 104/167 (62%), Gaps = 12/167 (7%) Frame = +3 Query: 6 IGVALNKVLDEGVVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IH 185 +G +N+ + EG+VKRE+LFITSK+W + P++V +A++ TL+DL LDY+DL L IH Sbjct: 60 VGEGINRAIKEGLVKREELFITSKLWNNFHDPKNVETALNKTLSDLNLDYVDLFL---IH 116 Query: 186 WP--FQIKKGSELSP--------ENFVELDMP--QTWRAMEKLYDSGKARAIGVSNFSTK 329 +P F+ E P +NF D+P TW+A+EKL ++GK ++IG+SNF+ Sbjct: 117 FPIAFKFVPIEEKYPPGFYCGDGDNFHYEDVPLLDTWKALEKLVEAGKIKSIGISNFTGA 176 Query: 330 KLADLLAVARVPPAVDQVECHPGWQQAKLRAFCRTNGVHFSAYAPLG 470 + DL+ A + PAV Q+E HP QQ KL + + G+ + Y+ G Sbjct: 177 LIYDLIRGATIKPAVLQIEHHPYLQQPKLIEYVQKAGIAITGYSSFG 223
>XYL1_CANTR (O13283) NAD(P)H-dependent D-xylose reductase I,II (EC 1.1.1.-)| (XR) Length = 324 Score = 119 bits (298), Expect = 4e-27 Identities = 68/167 (40%), Positives = 104/167 (62%), Gaps = 12/167 (7%) Frame = +3 Query: 6 IGVALNKVLDEGVVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IH 185 +G +N+ + EG+VKRE+LFITSK+W + P++V +A++ TL+DL LDY+DL L IH Sbjct: 60 VGEGINRAIKEGLVKREELFITSKLWNNFHDPKNVETALNKTLSDLNLDYVDLFL---IH 116 Query: 186 WP--FQIKKGSELSP--------ENFVELDMP--QTWRAMEKLYDSGKARAIGVSNFSTK 329 +P F+ E P +NF D+P TW+A+EKL ++GK ++IG+SNF+ Sbjct: 117 FPIAFKFVPIEEKYPPGFYCGDGDNFHYEDVPLLDTWKALEKLVEAGKIKSIGISNFTGA 176 Query: 330 KLADLLAVARVPPAVDQVECHPGWQQAKLRAFCRTNGVHFSAYAPLG 470 + DL+ A + PAV Q+E HP QQ KL + + G+ + Y+ G Sbjct: 177 LIYDLIRGATIKPAVLQIEHHPYLQQPKLIEYVQKAGIAITGYSSFG 223
>XYL1_KLULA (P49378) NAD(P)H-dependent D-xylose reductase (EC 1.1.1.-) (XR)| Length = 329 Score = 118 bits (295), Expect = 1e-26 Identities = 65/171 (38%), Positives = 97/171 (56%), Gaps = 16/171 (9%) Frame = +3 Query: 6 IGVALNKVLDEGVVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IH 185 +G +N+ + EG+VKREDL + SK+W S P++VP A++ TL+DLQLDY+D+ IH Sbjct: 58 VGQGVNRAIKEGLVKREDLVVVSKLWNSFHHPDNVPRALERTLSDLQLDYVDIFY---IH 114 Query: 186 WPFQIKK-------------GSELSPENFVE---LDMPQTWRAMEKLYDSGKARAIGVSN 317 +P K G E + +E + + TWRA+EKL D GK +++G+SN Sbjct: 115 FPLAFKPVPFDEKYPPGFYTGKEDEAKGHIEEEQVPLLDTWRALEKLVDQGKIKSLGISN 174 Query: 318 FSTKKLADLLAVARVPPAVDQVECHPGWQQAKLRAFCRTNGVHFSAYAPLG 470 FS + DLL AR+ P Q+E HP Q +L + + G+ AY+ G Sbjct: 175 FSGALIQDLLRGARIKPVALQIEHHPYLTQERLIKYVKNAGIQVVAYSSFG 225
>AK1E1_MOUSE (Q9DCT1) Aldo-keto reductase family 1 member E1 (EC 1.1.1.-)| Length = 301 Score = 117 bits (293), Expect = 2e-26 Identities = 69/163 (42%), Positives = 91/163 (55%), Gaps = 8/163 (4%) Frame = +3 Query: 6 IGVALNKVLDEGVVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IH 185 +G+ +++ + EGVVKREDLF+ SK+WC+ V +A TL L LDYLDL+L IH Sbjct: 46 VGMGISEKIKEGVVKREDLFVVSKLWCTCHKKSLVKTACTNTLEALNLDYLDLYL---IH 102 Query: 186 WPFQIKKGSELSPENFVELDMP------QTWRAMEKLYDSGKARAIGVSNFSTKKLADLL 347 WP K G + P + +P TW AME L G + +GVSNF+ ++L LL Sbjct: 103 WPMGFKPGEKDIPLDRNGKVIPSHTSFLDTWEAMEDLVFEGLVKNLGVSNFNHEQLERLL 162 Query: 348 --AVARVPPAVDQVECHPGWQQAKLRAFCRTNGVHFSAYAPLG 470 RV P +Q+ECHP Q KL FC V +AY PLG Sbjct: 163 DKPGLRVRPITNQIECHPYLNQKKLIDFCHKRNVSVTAYRPLG 205
>AK1BA_HUMAN (O60218) Aldo-keto reductase family 1 member B10 (EC 1.1.1.-)| (Aldose reductase-like) (ARL-1) (Small intestine reductase) (SI reductase) (Aldose reductase-related protein) (ARP) (hARP) Length = 316 Score = 116 bits (290), Expect = 4e-26 Identities = 66/163 (40%), Positives = 92/163 (56%), Gaps = 8/163 (4%) Frame = +3 Query: 6 IGVALNKVLDEGVVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IH 185 +G A+ + + E VKREDLFI SK+W + V A + TL DL+L YLD++L IH Sbjct: 55 VGEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYL---IH 111 Query: 186 WPFQIKKGSELSPENFV------ELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADLL 347 WP K G +L P++ + W AME+L D G +A+GVSNFS ++ LL Sbjct: 112 WPQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLL 171 Query: 348 --AVARVPPAVDQVECHPGWQQAKLRAFCRTNGVHFSAYAPLG 470 + P +QVECHP Q KL +C + G+ +AY+PLG Sbjct: 172 NKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLG 214
>ALD2_MOUSE (P45377) Aldose reductase-related protein 2 (EC 1.1.1.21) (AR)| (Aldehyde reductase) (Fibroblast growth factor-regulated protein) (FR-1 protein) Length = 315 Score = 115 bits (287), Expect = 8e-26 Identities = 64/163 (39%), Positives = 94/163 (57%), Gaps = 8/163 (4%) Frame = +3 Query: 6 IGVALNKVLDEGVVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IH 185 +G A+ + + E V+REDLFI SK+W + + + A TL DL+LDYLDL+L IH Sbjct: 54 VGEAIQEKIKEKAVQREDLFIVSKLWPTCFEKKLLKEAFQKTLTDLKLDYLDLYL---IH 110 Query: 186 WPFQIKKGSELSPEN------FVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADLL 347 WP ++ G EL P++ + + W ME+L D G +A+GVSNF+ ++ LL Sbjct: 111 WPQGLQPGKELFPKDDQGRILTSKTTFLEAWEGMEELVDQGLVKALGVSNFNHFQIERLL 170 Query: 348 --AVARVPPAVDQVECHPGWQQAKLRAFCRTNGVHFSAYAPLG 470 + P +QVECHP Q KL +C + G+ +AY+PLG Sbjct: 171 NKPGLKHKPVTNQVECHPYLTQEKLIQYCHSKGISVTAYSPLG 213
>XYL1_PACTA (P78736) NAD(P)H-dependent D-xylose reductase (EC 1.1.1.-) (XR)| Length = 318 Score = 114 bits (285), Expect = 1e-25 Identities = 67/167 (40%), Positives = 97/167 (58%), Gaps = 12/167 (7%) Frame = +3 Query: 6 IGVALNKVLDEGVVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IH 185 +G +N+ + +G+VKR+DLFITSK+W + A E+V A+ +L+D LDY DL+L+ H Sbjct: 54 VGEGINRAIKDGLVKRKDLFITSKLWNNFHAKENVKKALMKSLSDFNLDYFDLYLM---H 110 Query: 186 WPFQIK--KGSELSP--------ENFVELDMP--QTWRAMEKLYDSGKARAIGVSNFSTK 329 +P K E P + F+ D+P +TWRAME L D G ++IGVSN S Sbjct: 111 FPISFKFVPFEEKYPPGFYCGDGDKFIYEDVPIIETWRAMENLVDEGLVKSIGVSNVSGG 170 Query: 330 KLADLLAVARVPPAVDQVECHPGWQQAKLRAFCRTNGVHFSAYAPLG 470 L DL+ AR+ PA Q+E HP QQ KL + + G+ + Y+ G Sbjct: 171 LLEDLIKAARIKPASLQIEHHPYLQQNKLVEYAQLKGIVVTGYSNFG 217
>ALD2_CRIGR (O08782) Aldose reductase-related protein 2 (EC 1.1.1.21) (AR)| (Aldehyde reductase) (Aldo-keto reductase) Length = 315 Score = 114 bits (285), Expect = 1e-25 Identities = 63/163 (38%), Positives = 94/163 (57%), Gaps = 8/163 (4%) Frame = +3 Query: 6 IGVALNKVLDEGVVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IH 185 +G A+ + + E V+REDLFI SK+W + + + A TL DL+LDYLDL+L IH Sbjct: 54 VGEAIQEKIKEKAVRREDLFIVSKLWPTCFERKLLKEAFQKTLTDLKLDYLDLYL---IH 110 Query: 186 WPFQIKKGSELSPEN------FVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADLL 347 WP ++ G EL P++ ++ W ME+L D G +A+GVSNF+ ++ +L Sbjct: 111 WPQGLQPGKELFPKDDQGNVLTSKITFLDAWEVMEELVDEGLVKALGVSNFNHFQIERIL 170 Query: 348 --AVARVPPAVDQVECHPGWQQAKLRAFCRTNGVHFSAYAPLG 470 + P +QVECHP Q KL +C + G+ +AY+PLG Sbjct: 171 NKPGLKHKPVTNQVECHPYLTQEKLIEYCHSKGITVTAYSPLG 213
>ALD1_MOUSE (P21300) Aldose reductase-related protein 1 (EC 1.1.1.21) (AR)| (Aldehyde reductase) (VAS deferens androgen-dependent protein) (MVDP) (Aldo-keto reductase family 1 member B7) Length = 315 Score = 114 bits (284), Expect = 2e-25 Identities = 63/163 (38%), Positives = 93/163 (57%), Gaps = 8/163 (4%) Frame = +3 Query: 6 IGVALNKVLDEGVVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IH 185 +G A+ + + E VKREDLFI SK+W + V A TL+DL+LDYLDL+LV H Sbjct: 54 VGEAIQEKIKENAVKREDLFIVSKLWATFFEKSLVKKAFQNTLSDLKLDYLDLYLV---H 110 Query: 186 WPFQIKKGSELSPEN------FVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADLL 347 WP + G+ L P++ + W AME+L D G +A+G+SNF+ ++ LL Sbjct: 111 WPQGFQAGNALLPKDNKGKVLLSKSTFLDAWEAMEELVDQGLVKALGISNFNHFQIERLL 170 Query: 348 --AVARVPPAVDQVECHPGWQQAKLRAFCRTNGVHFSAYAPLG 470 + P +Q+E HP Q KL +C++ G+ +AY+PLG Sbjct: 171 NKPGLKHKPVTNQIESHPYLTQEKLIQYCQSKGIAVTAYSPLG 213
>DIDH_RAT (P23457) 3-alpha-hydroxysteroid dehydrogenase (EC 1.1.1.213)| (3-alpha-HSD) (Hydroxyprostaglandin dehydrogenase) Length = 322 Score = 112 bits (281), Expect = 4e-25 Identities = 60/163 (36%), Positives = 96/163 (58%), Gaps = 8/163 (4%) Frame = +3 Query: 6 IGVALNKVLDEGVVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IH 185 +G A+ +++G VKRED+F TSK+W + PE V + ++ TL QLDY+DL++ IH Sbjct: 61 VGQAIRSKIEDGTVKREDIFYTSKLWSTFHRPELVRTCLEKTLKSTQLDYVDLYI---IH 117 Query: 186 WPFQIKKGSELSPEN------FVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADLL 347 +P ++ G P + F +D+ TW AMEK D+G A++IGVSNF+ ++L +L Sbjct: 118 FPMALQPGDIFFPRDEHGKLLFETVDICDTWEAMEKCKDAGLAKSIGVSNFNCRQLERIL 177 Query: 348 --AVARVPPAVDQVECHPGWQQAKLRAFCRTNGVHFSAYAPLG 470 + P +QVECH Q+K+ +C++ + +Y LG Sbjct: 178 NKPGLKYKPVCNQVECHLYLNQSKMLDYCKSKDIILVSYCTLG 220
>AK1CD_MOUSE (Q8VC28) Aldo-keto reductase family 1 member C13 (EC 1.1.1.-)| Length = 323 Score = 112 bits (280), Expect = 5e-25 Identities = 63/166 (37%), Positives = 93/166 (56%), Gaps = 8/166 (4%) Frame = +3 Query: 6 IGVALNKVLDEGVVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IH 185 IG A+ + GVVKREDLFIT+K+WC+ PE V A++ +L LQLDY+DL++ +H Sbjct: 61 IGQAIQSKIKAGVVKREDLFITTKLWCTCFRPELVKPALEKSLKKLQLDYVDLYI---MH 117 Query: 186 WPFQIKKGSELSPEN------FVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADLL 347 +P +K G P N +D TW +E+ D+G ++IGVSNF+ ++L +L Sbjct: 118 YPVPMKSGDNDFPVNEQGKSLLDTVDFCDTWERLEECKDAGLVKSIGVSNFNHRQLERIL 177 Query: 348 --AVARVPPAVDQVECHPGWQQAKLRAFCRTNGVHFSAYAPLGRMK 479 + P +QVECH Q KL +C + + AY LG + Sbjct: 178 NKPGLKYKPVCNQVECHLYLNQRKLLDYCESKDIVLVAYGALGTQR 223
>P100_LEIMA (P22045) Probable reductase (EC 1.1.-.-)| Length = 284 Score = 112 bits (280), Expect = 5e-25 Identities = 66/150 (44%), Positives = 92/150 (61%), Gaps = 1/150 (0%) Frame = +3 Query: 45 VKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IHWPFQIKKGSE-LS 221 V RED+FIT+K+W ++ E +A + + L +DY+DL+L IHWP +G + LS Sbjct: 69 VPREDVFITTKLWNTEQGYESTLAAFEESRQKLGVDYIDLYL---IHWP----RGKDILS 121 Query: 222 PENFVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADLLAVARVPPAVDQVECHPGW 401 E LD +WRA E+LY K RAIGVSNF L D+LA+ V P V+QVE HP Sbjct: 122 KEGKKYLD---SWRAFEQLYKEKKVRAIGVSNFHIHHLEDVLAMCTVTPMVNQVELHPLN 178 Query: 402 QQAKLRAFCRTNGVHFSAYAPLGRMKVVAD 491 QA LRAFC + A++PLG+ K++++ Sbjct: 179 NQADLRAFCDAKQIKVEAWSPLGQGKLLSN 208
>CRO_RANTE (P02532) Rho crystallin| Length = 323 Score = 111 bits (278), Expect = 9e-25 Identities = 57/163 (34%), Positives = 91/163 (55%), Gaps = 8/163 (4%) Frame = +3 Query: 6 IGVALNKVLDEGVVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IH 185 IG + + +G VKRED+F T K+WC+ +PE V ++ +L D+ +DYLDL L +H Sbjct: 61 IGNGIRSKISDGTVKREDIFYTGKLWCTYFSPEMVRKGLERSLRDVGMDYLDLFL---MH 117 Query: 186 WPFQIKKGSELSPEN------FVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADLL 347 WP +K P + + +D+ TW A+E D+G R++GVSNF+ ++L +L Sbjct: 118 WPVSLKPSGASDPSDKDKPFIYDNVDLCATWEALEARKDAGLVRSLGVSNFNRRQLERIL 177 Query: 348 --AVARVPPAVDQVECHPGWQQAKLRAFCRTNGVHFSAYAPLG 470 + P +QVECH Q KL ++C++ + Y+ LG Sbjct: 178 NKPGLKYKPVCNQVECHVYLNQNKLHSYCKSKDIVLVTYSVLG 220
>AK1D1_HUMAN (P51857) 3-oxo-5-beta-steroid 4-dehydrogenase (EC 1.3.1.3)| (Delta(4)-3-ketosteroid 5-beta-reductase) (Aldo-keto reductase family 1 member D1) Length = 326 Score = 110 bits (275), Expect = 2e-24 Identities = 60/163 (36%), Positives = 96/163 (58%), Gaps = 8/163 (4%) Frame = +3 Query: 6 IGVALNKVLDEGVVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IH 185 +G A+ + + EG V+RED+F K+W ++ PE V ++ TL LQLDY+DL++ I Sbjct: 64 VGEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYI---IE 120 Query: 186 WPFQIKKGSELSPEN------FVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADLL 347 P K G E+ P + + + ++ TW AME D+G +++GVSNF+ ++L +L Sbjct: 121 VPMAFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELIL 180 Query: 348 --AVARVPPAVDQVECHPGWQQAKLRAFCRTNGVHFSAYAPLG 470 + P +QVECHP + Q KL FC+ + + +AY+PLG Sbjct: 181 NKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLG 223
>CRO_RANCA (P17264) Rho crystallin| Length = 323 Score = 110 bits (275), Expect = 2e-24 Identities = 56/163 (34%), Positives = 91/163 (55%), Gaps = 8/163 (4%) Frame = +3 Query: 6 IGVALNKVLDEGVVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IH 185 IG + + +G VKRED+F T K+WC+ +P+ V ++ +L D+ +DYLDL L +H Sbjct: 61 IGNGIRSKISDGTVKREDIFYTGKLWCTYFSPDMVRKGLERSLRDVGMDYLDLFL---MH 117 Query: 186 WPFQIKKGSELSPEN------FVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADLL 347 WP +K P + + +D+ TW A+E D+G R++GVSNF+ ++L +L Sbjct: 118 WPVSLKPSGASDPSDKDKPFIYDNVDLCATWEALEARKDAGLVRSLGVSNFNRRQLERIL 177 Query: 348 --AVARVPPAVDQVECHPGWQQAKLRAFCRTNGVHFSAYAPLG 470 + P +QVECH Q KL ++C++ + Y+ LG Sbjct: 178 NKPGLKYKPVCNQVECHVYLNQNKLHSYCKSKDIVLVTYSVLG 220
>S6PD_MALDO (P28475) NADP-dependent D-sorbitol-6-phosphate dehydrogenase (EC| 1.1.1.200) (Aldose-6-phosphate reductase [NADPH]) (NADP-S6PDH) Length = 310 Score = 109 bits (272), Expect = 5e-24 Identities = 67/165 (40%), Positives = 92/165 (55%), Gaps = 10/165 (6%) Frame = +3 Query: 6 IGVALNKVLDEGVVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IH 185 +G AL + G+VKRE+LFIT+KIW SD V A +L LQ+DYLDL+LV H Sbjct: 54 VGEALAEAFKTGLVKREELFITTKIWNSDHG--HVVEACKNSLEKLQIDYLDLYLV---H 108 Query: 186 WPFQIKKG------SELSPENFVELD----MPQTWRAMEKLYDSGKARAIGVSNFSTKKL 335 +P K S L + +++D + QTW MEK G R+IG+SN+ Sbjct: 109 YPMPTKHNAIGKTASLLGEDKVLDIDVTISLQQTWEGMEKTVSLGLVRSIGLSNYELFLT 168 Query: 336 ADLLAVARVPPAVDQVECHPGWQQAKLRAFCRTNGVHFSAYAPLG 470 D LA +++ PAV Q E HP +Q+ L FC +GV +A+ PLG Sbjct: 169 RDCLAYSKIKPAVSQFETHPYFQRDSLVKFCMKHGVLPTAHTPLG 213
>AK1D1_MOUSE (Q8VCX1) 3-oxo-5-beta-steroid 4-dehydrogenase (EC 1.3.99.6)| (Delta(4)-3-ketosteroid 5-beta-reductase) (Aldo-keto reductase family 1 member D1) Length = 325 Score = 106 bits (264), Expect = 4e-23 Identities = 57/163 (34%), Positives = 95/163 (58%), Gaps = 8/163 (4%) Frame = +3 Query: 6 IGVALNKVLDEGVVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IH 185 +G A+ + + EG VKRE++F K+W ++ P V A++ TL L+LDY+DL++ I Sbjct: 63 VGEAIREKIAEGKVKREEIFYCGKLWNTEHVPSMVLPALERTLKALKLDYIDLYI---IE 119 Query: 186 WPFQIKKGSELSPEN------FVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADLL 347 P K G E+ P + + + ++ TW A+E D+G +++GVSNF+ ++L +L Sbjct: 120 LPMAFKPGKEIYPRDENGRIIYDKTNLCATWEALEACKDAGLVKSLGVSNFNRRQLELIL 179 Query: 348 --AVARVPPAVDQVECHPGWQQAKLRAFCRTNGVHFSAYAPLG 470 + P +QVECHP + Q KL FC+ + + A++PLG Sbjct: 180 NKPGLKYKPVTNQVECHPYFTQTKLLKFCQQHDIVIVAHSPLG 222
>DTDH_MUCMU (Q01213) 4-dihydromethyl-trisporate dehydrogenase (EC 1.1.1.-)| (4-dihydromethyl-TA dehydrogenase) Length = 321 Score = 105 bits (263), Expect = 5e-23 Identities = 58/167 (34%), Positives = 93/167 (55%), Gaps = 12/167 (7%) Frame = +3 Query: 6 IGVALNKVLDEGVVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IH 185 +G +NK ++EG+VKREDLFI +K+W + + + V + D L D L+Y DL+L IH Sbjct: 57 VGRGINKAINEGLVKREDLFIVTKLWNTFHSKKHVRALFDRQLKDTGLEYFDLYL---IH 113 Query: 186 WPFQIKKGS------------ELSPENFVELDMPQTWRAMEKLYDSGKARAIGVSNFSTK 329 +P ++ + F + + + W +EK+ D+G AR IGV+NF+ + Sbjct: 114 FPVPLQYVDPATVYPPGWYVGDAKSLQFEQSPIHECWAELEKIVDAGLARNIGVANFNCQ 173 Query: 330 KLADLLAVARVPPAVDQVECHPGWQQAKLRAFCRTNGVHFSAYAPLG 470 + DLL AR+ PAV Q+E HP Q +L + + G+ +AY+ G Sbjct: 174 AILDLLTYARIKPAVLQIELHPYLPQERLVKWVKEQGIQITAYSSFG 220
>XYL1_CANPA (Q6Y0Z3) NADH-dependent D-xylose reductase (EC 1.1.1.175) (XR)| Length = 324 Score = 105 bits (261), Expect = 9e-23 Identities = 63/170 (37%), Positives = 92/170 (54%), Gaps = 15/170 (8%) Frame = +3 Query: 6 IGVALNKVLDEGVVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IH 185 +G + + + EG+VKRE+LFITSK+W S ++V A+ TL+DL LDY+DL IH Sbjct: 60 VGEGIKRAIKEGIVKREELFITSKLWNSFHDKKNVEVALMKTLSDLNLDYVDLFY---IH 116 Query: 186 WP---------------FQIKKGSELSPENFVELDMPQTWRAMEKLYDSGKARAIGVSNF 320 +P F G + S E LD TWRA+EKL D G A++IG+SNF Sbjct: 117 FPIAQKPVPIEKKYPPGFYCGDGDKWSIEEVPLLD---TWRALEKLVDQGLAKSIGISNF 173 Query: 321 STKKLADLLAVARVPPAVDQVECHPGWQQAKLRAFCRTNGVHFSAYAPLG 470 S + + DL+ + P Q+E HP Q KL + + + + + Y+ G Sbjct: 174 SAQLIYDLIRGCTIKPVALQIEHHPYLTQPKLVEYVQLHDIQITGYSSFG 223
>AK1CD_MESAU (P82809) Aldo-keto reductase family 1 member C13 (EC 1.1.1.-)| (Morphine 6-dehydrogenase) (EC 1.1.1.218) Length = 322 Score = 102 bits (255), Expect = 4e-22 Identities = 57/166 (34%), Positives = 93/166 (56%), Gaps = 8/166 (4%) Frame = +3 Query: 6 IGVALNKVLDEGVVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IH 185 IG A+ + G+VKRED+FIT+K+WC+ PE V +++ LQL+++DL + +H Sbjct: 61 IGQAIQSNIKAGIVKREDMFITTKLWCTCFQPELVRPSLEKXXXKLQLEHVDLFI---MH 117 Query: 186 WPFQIKKGSELSPEN------FVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADLL 347 +P +K G P + +D TW A+EK D+G ++IGVSNF+ ++L +L Sbjct: 118 YPVPMKAGDNDFPLDEQGKLLLDTVDFCATWEALEKXXDAGLVKSIGVSNFNMRQLERIL 177 Query: 348 --AVARVPPAVDQVECHPGWQQAKLRAFCRTNGVHFSAYAPLGRMK 479 + P +QVECH Q+KL +C++ + A+ LG + Sbjct: 178 NKPGLKYKPVCNQVECHVYNNQSKLLDYCKSKDIVLVAFGALGTQR 223
>AK1D1_RAT (P31210) 3-oxo-5-beta-steroid 4-dehydrogenase (EC 1.3.99.6)| (Delta(4)-3-ketosteroid 5-beta-reductase) (Aldo-keto reductase family 1 member D1) Length = 326 Score = 102 bits (253), Expect = 7e-22 Identities = 59/164 (35%), Positives = 94/164 (57%), Gaps = 9/164 (5%) Frame = +3 Query: 6 IGVALNKVLDEGVVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IH 185 +G A+ + + EG VKRE++F K+W +D PE V A++ TL L+LDY+DL++ I Sbjct: 63 VGEAIREKVAEGKVKREEIFYCGKLWSTDHDPEMVRPALERTLQTLKLDYIDLYI---IE 119 Query: 186 WPFQIKKGSELSPEN------FVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADLL 347 P K G E P++ + + ++ TW A+E D+G +++GVSNF+ ++L +L Sbjct: 120 MPMAFKPGEEFYPKDENGRVIYHKSNLCATWEALEACKDAGLVKSLGVSNFNRRQLEVIL 179 Query: 348 --AVARVPPAVDQVECHPGWQQAKLRAFCRTNGVHF-SAYAPLG 470 + P +QVECHP + Q KL ++ F AY+PLG Sbjct: 180 NKPGLKYKPVTNQVECHPYFTQTKLLEVSASSMTSFIVAYSPLG 223
>GCY_YEAST (P14065) GCY protein (EC 1.1.1.-)| Length = 312 Score = 102 bits (253), Expect = 7e-22 Identities = 62/172 (36%), Positives = 98/172 (56%), Gaps = 21/172 (12%) Frame = +3 Query: 18 LNKVLDEGVVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IHWPFQ 197 + + + + V RE++F+T+K+WC+ +V A+D +L L LDY+DL+L+ HWP + Sbjct: 62 VGQAIKDSGVPREEIFVTTKLWCTQHHEPEV--ALDQSLKRLGLDYVDLYLM---HWPAR 116 Query: 198 I----------------KKGS---ELSPENFVELDMPQTWRAMEKLYDSGKARAIGVSNF 320 + K GS +++ NF++ TW M++L +GK +A+GVSNF Sbjct: 117 LDPAYIKNEDILSVPTKKDGSRAVDITNWNFIK-----TWELMQELPKTGKTKAVGVSNF 171 Query: 321 STKKLADLLAVA--RVPPAVDQVECHPGWQQAKLRAFCRTNGVHFSAYAPLG 470 S L DLLA ++ PA +QVE HP Q +L FC++ G+ AY+PLG Sbjct: 172 SINNLKDLLASQGNKLTPAANQVEIHPLLPQDELINFCKSKGIVVEAYSPLG 223
>ARA1_YEAST (P38115) D-arabinose dehydrogenase [NAD(P)+] heavy chain (EC| 1.1.1.117) Length = 344 Score = 101 bits (252), Expect = 1e-21 Identities = 63/173 (36%), Positives = 100/173 (57%), Gaps = 18/173 (10%) Frame = +3 Query: 6 IGVALNKVLDEGVVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IH 185 +G A+ ++L++G +KREDLFIT+K+W + ++V +++ +L L L+Y+DL L H Sbjct: 77 VGEAIKELLEDGSIKREDLFITTKVW--PVLWDEVDRSLNESLKALGLEYVDLLLQ---H 131 Query: 186 WPFQIKK--------GSELSPEN-------FVELDMPQTWRAMEKLY---DSGKARAIGV 311 WP +K G +P + + D +T++ +EK+Y + + RAIGV Sbjct: 132 WPLCFEKIKDPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGV 191 Query: 312 SNFSTKKLADLLAVARVPPAVDQVECHPGWQQAKLRAFCRTNGVHFSAYAPLG 470 SNFS + L L+ RV P V+QVE HP Q +LR FC + + +AY+PLG Sbjct: 192 SNFSIEYLERLIKECRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLG 244
>AK1D1_RABIT (Q9TV64) 3-oxo-5-beta-steroid 4-dehydrogenase (EC 1.3.99.6)| (Delta(4)-3-ketosteroid 5-beta-reductase) (Aldo-keto reductase family 1 member D1) Length = 326 Score = 99.4 bits (246), Expect = 5e-21 Identities = 56/163 (34%), Positives = 91/163 (55%), Gaps = 8/163 (4%) Frame = +3 Query: 6 IGVALNKVLDEGVVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IH 185 +G + + EG V+RED+F K+W ++ P V ++ TL L+LDY+DL++ I Sbjct: 64 VGETFREKIAEGKVRREDIFYCGKLWATNHDPVMVRPTLERTLKVLKLDYIDLYI---IE 120 Query: 186 WPFQIKKGSELSPEN------FVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADLL 347 P K G + P + + + ++ TW A+E D+G +++GVSNF+ ++L LL Sbjct: 121 IPMAFKPGDVVYPRDENGKWLYHKTNLCATWEALEACKDAGLVKSLGVSNFNRQQLELLL 180 Query: 348 --AVARVPPAVDQVECHPGWQQAKLRAFCRTNGVHFSAYAPLG 470 + P +QVECHP + Q KL FC+ + + AY+PLG Sbjct: 181 NKPGLKHKPVCNQVECHPYFTQPKLLKFCQQHDIIIVAYSPLG 223
>GRE3_YEAST (P38715) NADPH-dependent aldose reductase GRE3 (EC 1.1.1.21)| (NADPH-dependent aldo-keto reductase GRE3) (NADPH-dependent methylglyoxal reductase GRE3) (EC 1.1.1.-) (Xylose reductase) (EC 1.1.1.-) (Genes de respuesta a estres protein 3) Length = 327 Score = 99.0 bits (245), Expect = 6e-21 Identities = 60/171 (35%), Positives = 88/171 (51%), Gaps = 16/171 (9%) Frame = +3 Query: 6 IGVALNKVLDEGVVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IH 185 +G + K + EG+V R+D+F+ SK+W + P+ V A+ TL+D+ LDYLDL+ IH Sbjct: 55 VGEGIRKAISEGLVSRKDIFVVSKLWNNFHHPDHVKLALKKTLSDMGLDYLDLYY---IH 111 Query: 186 WPFQIK--KGSELSPENF------------VELDMP--QTWRAMEKLYDSGKARAIGVSN 317 +P K E P F E +P T+RA+E+ D G ++IGVSN Sbjct: 112 FPIAFKYVPFEEKYPPGFYTGADDEKKGHITEAHVPIIDTYRALEECVDEGLIKSIGVSN 171 Query: 318 FSTKKLADLLAVARVPPAVDQVECHPGWQQAKLRAFCRTNGVHFSAYAPLG 470 F + DLL R+ P Q+E HP Q L FC+ + + AY+ G Sbjct: 172 FQGSLIQDLLRGCRIKPVALQIEHHPYLTQEHLVEFCKLHDIQVVAYSSFG 222
>XYL1_TRIRE (Q876L8) NAD(P)H-dependent D-xylose reductase (EC 1.1.1.-) (XR)| Length = 324 Score = 98.2 bits (243), Expect = 1e-20 Identities = 61/167 (36%), Positives = 87/167 (52%), Gaps = 13/167 (7%) Frame = +3 Query: 9 GVALNKVLDEGVVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IHW 188 G + + + +G+VKREDLFI SK+W + + V L D Q+DY DL LV H+ Sbjct: 57 GEGVARAIKDGLVKREDLFIVSKLWQTFHDEDKVEPITRRQLADWQIDYFDLFLV---HF 113 Query: 189 PFQIK---KGSELSPENFVE----------LDMPQTWRAMEKLYDSGKARAIGVSNFSTK 329 P ++ P F + + QTW AME+L D G AR+IGVSN+ + Sbjct: 114 PAALEYVDPSVRYPPGWFYDGKSEVRWSKTTTLQQTWGAMERLVDKGLARSIGVSNYQAQ 173 Query: 330 KLADLLAVARVPPAVDQVECHPGWQQAKLRAFCRTNGVHFSAYAPLG 470 + D L AR+ PA Q+E HP QQ L + +T G+ +AY+ G Sbjct: 174 SVYDALIYARIKPATLQIEHHPYLQQPDLVSLAQTEGIVVTAYSSFG 220
>XYL1_ASPNG (Q9P8R5) NAD(P)H-dependent D-xylose reductase (EC 1.1.1.-) (XR)| Length = 319 Score = 97.8 bits (242), Expect = 1e-20 Identities = 59/165 (35%), Positives = 86/165 (52%), Gaps = 11/165 (6%) Frame = +3 Query: 9 GVALNKVLDEGVVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IHW 188 G + + + +G+VKRE+LFI SK+W S + V L D +DY DL++V H+ Sbjct: 57 GQGIARAIKDGLVKREELFIVSKLWNSFHDGDRVEPICRKQLADWGIDYFDLYIV---HF 113 Query: 189 PFQIKK-----------GSELSPENFVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKL 335 P +K SE F + +TW AME L D AR+IG+SNFS + + Sbjct: 114 PISLKYVDPAVRYPPGWKSEKDELEFGNATIQETWTAMESLVDKKLARSIGISNFSAQLV 173 Query: 336 ADLLAVARVPPAVDQVECHPGWQQAKLRAFCRTNGVHFSAYAPLG 470 DLL AR+ PA Q+E HP Q +L + + G+ +AY+ G Sbjct: 174 MDLLRYARIRPATLQIEHHPYLTQTRLVEYAQKEGLTVTAYSSFG 218
>YPR1_YEAST (Q12458) Putative reductase 1 (EC 1.1.1.-)| Length = 312 Score = 96.3 bits (238), Expect = 4e-20 Identities = 58/167 (34%), Positives = 95/167 (56%), Gaps = 16/167 (9%) Frame = +3 Query: 18 LNKVLDEGVVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IHWPFQ 197 + + + + V RE++FIT+K+W ++ D +A++ +L L LDY+DL+L+ HWP Sbjct: 62 VGRAIKDSGVPREEIFITTKLWGTE--QRDPEAALNKSLKRLGLDYVDLYLM---HWPVP 116 Query: 198 IKK-----GSELS----PENFVELDMPQ-----TWRAMEKLYDSGKARAIGVSNFSTKKL 335 +K G+ L + V++D + TW M++L +GK +A+GVSNFS + Sbjct: 117 LKTDRVTDGNVLCIPTLEDGTVDIDTKEWNFIKTWELMQELPKTGKTKAVGVSNFSINNI 176 Query: 336 ADLLAVA--RVPPAVDQVECHPGWQQAKLRAFCRTNGVHFSAYAPLG 470 +LL +V PA +Q+E HP Q +L AFC+ G+ AY+P G Sbjct: 177 KELLESPNNKVVPATNQIEIHPLLPQDELIAFCKEKGIVVEAYSPFG 223
>YOF5_CAEEL (Q09632) Probable oxidoreductase ZK1290.5 in chromosome II (EC| 1.-.-.-) Length = 321 Score = 93.2 bits (230), Expect = 3e-19 Identities = 54/149 (36%), Positives = 80/149 (53%) Frame = +3 Query: 45 VKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IHWPFQIKKGSELSP 224 V RE++F+++K+W D E V +A T+ LQ DYLD++++ P I E Sbjct: 64 VPREEMFLSTKLWPVDCGDE-VYNAFQTSCEKLQTDYLDMYMIHMPQLPDWIVNQKETKE 122 Query: 225 ENFVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADLLAVARVPPAVDQVECHPGWQ 404 + TWR ME LY+ R+IGVSN+S + L +LL A + P +QVE HP + Sbjct: 123 K---------TWRQMELLYEDEHVRSIGVSNYSIEDLDELLEFASILPHANQVELHPWFH 173 Query: 405 QAKLRAFCRTNGVHFSAYAPLGRMKVVAD 491 QA L+ +C G+ Y PL + K + D Sbjct: 174 QADLKNYCDELGILTMGYCPLAKGKYLED 202
>MORA_PSEPU (Q02198) Morphine 6-dehydrogenase (EC 1.1.1.218) (Naloxone| reductase) Length = 295 Score = 90.1 bits (222), Expect = 3e-18 Identities = 53/142 (37%), Positives = 80/142 (56%) Frame = +3 Query: 45 VKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IHWPFQIKKGSELSP 224 V R ++F+T+K++ D E A D +L L LDY+DL+L +HWP + + Sbjct: 66 VDRAEMFVTTKLFNCDYGYERALRAFDESLGRLGLDYVDLYL---LHWPTKDWNATI--- 119 Query: 225 ENFVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADLLAVARVPPAVDQVECHPGWQ 404 Q+W+A EK+ G+ARAIGV NF +L +L+A + V PAV+Q+E HP + Sbjct: 120 ---------QSWKAAEKILGDGRARAIGVCNFLEDQLDELIAASDVVPAVNQIELHPYFA 170 Query: 405 QAKLRAFCRTNGVHFSAYAPLG 470 Q L A R G+ A++P+G Sbjct: 171 QKPLLAKNRALGIVTEAWSPIG 192
>DKGA_YERPE (Q8ZI40) 2,5-diketo-D-gluconic acid reductase A (EC 1.1.1.274)| (2,5-DKG reductase A) (2,5-DKGR A) (25DKGR-A) (AKR5C) Length = 277 Score = 86.7 bits (213), Expect = 3e-17 Identities = 52/152 (34%), Positives = 82/152 (53%) Frame = +3 Query: 18 LNKVLDEGVVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IHWPFQ 197 + K L V R++LFIT+K+W D + A++T+L LQLDY+DL+L IHWP Sbjct: 57 VGKALKAAAVARDELFITTKLWNDD--QHNPQQALETSLQKLQLDYVDLYL---IHWP-- 109 Query: 198 IKKGSELSPENFVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADLLAVARVPPAVD 377 + +++V WR + L + G R+IGV NF L L+ + P V+ Sbjct: 110 -----DPKQDHYVS-----AWRELVTLKEQGLIRSIGVCNFHIPHLQRLIDETGIAPTVN 159 Query: 378 QVECHPGWQQAKLRAFCRTNGVHFSAYAPLGR 473 Q+E HP QQ +L A+ T+ + +++PL + Sbjct: 160 QIELHPLLQQRQLHAWNATHHIATESWSPLAQ 191
>DKGA_SALTI (P58744) 2,5-diketo-D-gluconic acid reductase A (EC 1.1.1.274)| (2,5-DKG reductase A) (2,5-DKGR A) (25DKGR-A) (AKR5C) Length = 275 Score = 85.1 bits (209), Expect = 9e-17 Identities = 52/152 (34%), Positives = 80/152 (52%) Frame = +3 Query: 18 LNKVLDEGVVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IHWPFQ 197 + K L V RE+LFIT+K+W D + A+ +L LQLDYLDL+L+ HWP Sbjct: 57 VGKALKAASVAREELFITTKLWNDD--QKRPREALQESLKKLQLDYLDLYLM---HWPVP 111 Query: 198 IKKGSELSPENFVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADLLAVARVPPAVD 377 + +++V+ W+ M L G ++IGV NF L L+ VPP ++ Sbjct: 112 -------AIDHYVD-----AWKGMIALQKEGLVKSIGVCNFQIHHLQRLIDETGVPPVIN 159 Query: 378 QVECHPGWQQAKLRAFCRTNGVHFSAYAPLGR 473 Q+E HP QQ +L A T+ + +++PL + Sbjct: 160 QIELHPLMQQRQLHAXNATHKIQTESWSPLAQ 191
>DKGA_CORSC (P06632) 2,5-diketo-D-gluconic acid reductase A (EC 1.1.1.274)| (2,5-DKG reductase A) (2,5-DKGR A) (25DKGR-A) (AKR5C) Length = 277 Score = 83.2 bits (204), Expect = 4e-16 Identities = 50/145 (34%), Positives = 78/145 (53%) Frame = +3 Query: 45 VKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IHWPFQIKKGSELSP 224 + R+DLFIT+K+W ++ +AI +L L LD +DL+LV HWP + Sbjct: 64 IARDDLFITTKLWNDRHDGDEPAAAIAESLAKLALDQVDLYLV---HWPTP-------AA 113 Query: 225 ENFVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADLLAVARVPPAVDQVECHPGWQ 404 +N+V W M +L +G R+IGVSN L ++A V PAV+Q+E HP +Q Sbjct: 114 DNYVH-----AWEKMIELRAAGLTRSIGVSNHLVPHLERIVAATGVVPAVNQIELHPAYQ 168 Query: 405 QAKLRAFCRTNGVHFSAYAPLGRMK 479 Q ++ + + V ++ PLG+ K Sbjct: 169 QREITDWAAAHDVKIESWGPLGQGK 193
>DKGA_SALTY (Q8ZM06) 2,5-diketo-D-gluconic acid reductase A (EC 1.1.1.274)| (2,5-DKG reductase A) (2,5-DKGR A) (25DKGR-A) (AKR5C) Length = 275 Score = 82.8 bits (203), Expect = 5e-16 Identities = 51/152 (33%), Positives = 80/152 (52%) Frame = +3 Query: 18 LNKVLDEGVVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IHWPFQ 197 + K L V RE+LFIT+K+W D + A+ +L LQLDYLDL+L+ HWP Sbjct: 57 VGKALKAASVAREELFITTKLWNDD--QKRPREALQESLKKLQLDYLDLYLM---HWPVP 111 Query: 198 IKKGSELSPENFVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADLLAVARVPPAVD 377 + +++V+ W+ M L G ++IGV NF L L+ V P ++ Sbjct: 112 -------AIDHYVD-----AWKGMIALQKEGLVKSIGVCNFQIHHLQRLIDETGVTPVIN 159 Query: 378 QVECHPGWQQAKLRAFCRTNGVHFSAYAPLGR 473 Q+E HP QQ +L A+ T+ + +++PL + Sbjct: 160 QIELHPLMQQRQLHAWNATHKIQTESWSPLAQ 191
>DKGA_ECOLI (Q46857) 2,5-diketo-D-gluconic acid reductase A (EC 1.1.1.274)| (2,5-DKG reductase A) (2,5-DKGR A) (25DKGR-A) (AKR5C) Length = 275 Score = 82.4 bits (202), Expect = 6e-16 Identities = 51/152 (33%), Positives = 81/152 (53%) Frame = +3 Query: 18 LNKVLDEGVVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IHWPFQ 197 + K L V RE+LFIT+K+W D + A+ +L LQLDY+DL+L+ HWP Sbjct: 57 VGKALKNASVNREELFITTKLWNDD--HKRPREALLDSLKKLQLDYIDLYLM---HWPVP 111 Query: 198 IKKGSELSPENFVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADLLAVARVPPAVD 377 + +++VE W+ M +L G ++IGV NF L L+ V P ++ Sbjct: 112 -------AIDHYVE-----AWKGMIELQKEGLIKSIGVCNFQIHHLQRLIDETGVTPVIN 159 Query: 378 QVECHPGWQQAKLRAFCRTNGVHFSAYAPLGR 473 Q+E HP QQ +L A+ T+ + +++PL + Sbjct: 160 QIELHPLMQQRQLHAWNATHKIQTESWSPLAQ 191
>DKGA_ECO57 (Q8XBT6) 2,5-diketo-D-gluconic acid reductase A (EC 1.1.1.274)| (2,5-DKG reductase A) (2,5-DKGR A) (25DKGR-A) (AKR5C) Length = 275 Score = 82.0 bits (201), Expect = 8e-16 Identities = 52/153 (33%), Positives = 82/153 (53%), Gaps = 1/153 (0%) Frame = +3 Query: 18 LNKVLDEGVVKREDLFITSKIWCSDL-APEDVPSAIDTTLNDLQLDYLDLHLVT*IHWPF 194 + K L V RE+LFIT+K+W D P + A+ +L LQLDY+DL+L+ HWP Sbjct: 57 VGKALKNASVNREELFITTKLWNDDHNRPRE---ALLDSLKKLQLDYIDLYLM---HWPV 110 Query: 195 QIKKGSELSPENFVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADLLAVARVPPAV 374 + +++VE W+ M +L G ++IGV NF L L+ V P + Sbjct: 111 P-------AIDHYVE-----AWKGMIELQKEGLIKSIGVCNFQIHHLQRLIDETGVTPVI 158 Query: 375 DQVECHPGWQQAKLRAFCRTNGVHFSAYAPLGR 473 +Q+E HP QQ +L A+ T+ + +++PL + Sbjct: 159 NQIELHPLMQQRQLHAWNATHKIQTESWSPLAQ 191
>YJ66_YEAST (P47137) Probable oxidoreductase YJR096W (EC 1.-.-.-)| Length = 282 Score = 79.3 bits (194), Expect = 5e-15 Identities = 53/148 (35%), Positives = 81/148 (54%), Gaps = 3/148 (2%) Frame = +3 Query: 33 DEGVVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQ-LDYLDLHLVT*IHWPFQIKKG 209 D G KRE++F T+K+W S + +AI LN++ L Y+DL L IH P + G Sbjct: 67 DPGNHKREEIFYTTKLWNSQNGYKRAKAAIRQCLNEVSGLQYIDLLL---IHSPLE---G 120 Query: 210 SELSPENFVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADLL--AVARVPPAVDQV 383 S+L E TWRAM++ D G ++IGVSN+ K + +LL + P V+Q+ Sbjct: 121 SKLRLE---------TWRAMQEAVDEGLVKSIGVSNYGKKHIDELLNWPELKHKPVVNQI 171 Query: 384 ECHPGWQQAKLRAFCRTNGVHFSAYAPL 467 E P + +L +C++ G+ A+APL Sbjct: 172 EISPWIMRQELADYCKSKGLVVEAFAPL 199
>DKGB_CORSS (P15339) 2,5-diketo-D-gluconic acid reductase B (EC 1.1.1.274)| (2,5-DKG reductase B) (2,5-DKGR B) (25DKGR-B) (AKR5D) Length = 276 Score = 79.0 bits (193), Expect = 7e-15 Identities = 54/143 (37%), Positives = 75/143 (52%) Frame = +3 Query: 45 VKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IHWPFQIKKGSELSP 224 V R++L + SKI + +I +L+ L LD +DL L IHWP +P Sbjct: 65 VDRDELIVASKIPGRQHGRAEAVDSIRGSLDRLGLDVIDLQL---IHWP---------NP 112 Query: 225 ENFVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADLLAVARVPPAVDQVECHPGWQ 404 LD TWR M ++G R+IGVSNF+ L L+ V PAV+QVE HP + Sbjct: 113 SVGRWLD---TWRGMIDAREAGLVRSIGVSNFTEPMLKTLIDETGVTPAVNQVELHPYFP 169 Query: 405 QAKLRAFCRTNGVHFSAYAPLGR 473 QA LRAF +G+ +++PL R Sbjct: 170 QAALRAFHDEHGIRTESWSPLAR 192
>DKGB_ECOLI (P30863) 2,5-diketo-D-gluconic acid reductase B (EC 1.1.1.274)| (2,5-DKG reductase B) (2,5-DKGR B) (25DKGR-B) (AKR5D) Length = 267 Score = 75.9 bits (185), Expect = 6e-14 Identities = 49/160 (30%), Positives = 83/160 (51%), Gaps = 1/160 (0%) Frame = +3 Query: 15 ALNKVLDEGVVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IHWPF 194 A+ + + E V R +L+IT+KIW +L+ + + ++ +L L+ DY+DL L IHWP Sbjct: 44 AVGQAIAESGVPRHELYITTKIWIENLSKDKLIPSLKESLQKLRTDYVDLTL---IHWP- 99 Query: 195 QIKKGSELSPENFVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLAD-LLAVARVPPA 371 E+S E F++ A+ + G R IG+SNF+ + + AV A Sbjct: 100 --SPNDEVSVEEFMQ--------ALLEAKKQGLTREIGISNFTIPLMEKAIAAVGAENIA 149 Query: 372 VDQVECHPGWQQAKLRAFCRTNGVHFSAYAPLGRMKVVAD 491 +Q+E P Q K+ A+ + +G+H ++Y L K + D Sbjct: 150 TNQIELSPYLQNRKVVAWAKQHGIHITSYMTLAYGKALKD 189
>DKGB_ECO57 (Q8X7Z7) 2,5-diketo-D-gluconic acid reductase B (EC 1.1.1.274)| (2,5-DKG reductase B) (2,5-DKGR B) (25DKGR-B) (AKR5D) Length = 267 Score = 74.7 bits (182), Expect = 1e-13 Identities = 49/160 (30%), Positives = 82/160 (51%), Gaps = 1/160 (0%) Frame = +3 Query: 15 ALNKVLDEGVVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IHWPF 194 A+ + E V R +L+IT+KIW +L+ + + ++ +L L+ DY+DL L IHWP Sbjct: 44 AVGLAIAESGVPRHELYITTKIWIENLSKDKLIPSLKESLQKLRTDYVDLTL---IHWP- 99 Query: 195 QIKKGSELSPENFVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLAD-LLAVARVPPA 371 E+S E F++ A+ + G R IG+SNF+ + + AV A Sbjct: 100 --SPNDEVSVEEFMQ--------ALLEAKKEGLTREIGISNFTIPLMEKAIAAVGAENIA 149 Query: 372 VDQVECHPGWQQAKLRAFCRTNGVHFSAYAPLGRMKVVAD 491 +Q+E P Q K+ A+ + +G+H ++Y L K + D Sbjct: 150 TNQIELSPYLQNRKVVAWAKQHGIHITSYMTLAYGKALKD 189
>DKGB_SALTY (Q8ZRM7) 2,5-diketo-D-gluconic acid reductase B (EC 1.1.1.274)| (2,5-DKG reductase B) (2,5-DKGR B) (25DKGR-B) (AKR5D) Length = 267 Score = 73.6 bits (179), Expect = 3e-13 Identities = 48/160 (30%), Positives = 82/160 (51%), Gaps = 1/160 (0%) Frame = +3 Query: 15 ALNKVLDEGVVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IHWPF 194 A+ + + E V R +L+IT+KIW +L+ + + ++ +L L+ DY+DL L IHWP Sbjct: 44 AVGQAIAESGVPRNELYITTKIWIENLSKDKLIPSLKESLKKLRTDYVDLTL---IHWP- 99 Query: 195 QIKKGSELSPENFVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLAD-LLAVARVPPA 371 G +S E F++ A+ + G R IG+SNF+ + + AV A Sbjct: 100 --SPGDAVSVEEFMQ--------ALLEAKKQGLTREIGISNFTIPLMEKAIAAVGADNIA 149 Query: 372 VDQVECHPGWQQAKLRAFCRTNGVHFSAYAPLGRMKVVAD 491 +Q+E P Q K+ + + +G+H ++Y L K + D Sbjct: 150 TNQIELSPYLQNRKVVDWAKAHGIHITSYMTLAYGKALKD 189
>DKGB_SALTI (Q8Z988) 2,5-diketo-D-gluconic acid reductase B (EC 1.1.1.274)| (2,5-DKG reductase B) (2,5-DKGR B) (25DKGR-B) (AKR5D) Length = 267 Score = 73.6 bits (179), Expect = 3e-13 Identities = 48/160 (30%), Positives = 82/160 (51%), Gaps = 1/160 (0%) Frame = +3 Query: 15 ALNKVLDEGVVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IHWPF 194 A+ + + E V R +L+IT+KIW +L+ + + ++ +L L+ DY+DL L IHWP Sbjct: 44 AVGQAIAESGVPRNELYITTKIWIENLSKDKLIPSLKESLKKLRTDYVDLTL---IHWP- 99 Query: 195 QIKKGSELSPENFVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLAD-LLAVARVPPA 371 G +S E F++ A+ + G R IG+SNF+ + + AV A Sbjct: 100 --SPGDAVSVEEFMQ--------ALLEAKKQGLTREIGISNFTIPLMEKAIAAVGADHIA 149 Query: 372 VDQVECHPGWQQAKLRAFCRTNGVHFSAYAPLGRMKVVAD 491 +Q+E P Q K+ + + +G+H ++Y L K + D Sbjct: 150 TNQIELSPYLQNRKVVDWAKAHGIHITSYMTLAYGKALKD 189
>DKGB_YERPE (Q8ZH36) 2,5-diketo-D-gluconic acid reductase B (EC 1.1.1.274)| (2,5-DKG reductase B) (2,5-DKGR B) (25DKGR-B) (AKR5D) Length = 267 Score = 69.3 bits (168), Expect = 5e-12 Identities = 45/159 (28%), Positives = 81/159 (50%), Gaps = 1/159 (0%) Frame = +3 Query: 18 LNKVLDEGVVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IHWPFQ 197 + + + E + R++LFIT+KIW ++L+ + + ++ ++ L+ DY+DL L IHWP Sbjct: 45 VGQAIQESGINRDELFITTKIWIANLSKDKLIPSLRESIQKLKTDYVDLTL---IHWP-- 99 Query: 198 IKKGSELSPENFVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLAD-LLAVARVPPAV 374 SP + E+ + + + K G R IG+SNF+ + + AV A Sbjct: 100 -------SPND--EVSVAEFMSELLKAKGLGLTRQIGISNFTIDLMKQAIAAVGAEEIAT 150 Query: 375 DQVECHPGWQQAKLRAFCRTNGVHFSAYAPLGRMKVVAD 491 +Q+E P Q + F + NG+ ++Y L K +A+ Sbjct: 151 NQIELSPLLQNRNVVDFAKQNGIAVTSYMTLAYGKALAE 189
>GS69_BACSU (P80874) General stress protein 69 (EC 1.1.1.-) (GSP69) (AKR11B)| Length = 331 Score = 52.0 bits (123), Expect = 9e-07 Identities = 30/79 (37%), Positives = 45/79 (56%) Frame = +3 Query: 120 IDTTLNDLQLDYLDLHLVT*IHWPFQIKKGSELSPENFVELDMPQTWRAMEKLYDSGKAR 299 ++ +L LQ DY+DL+ V HWP + + + +T M++LYD+GK R Sbjct: 107 VENSLKRLQTDYIDLYQV---HWPDPL-------------VPIEETAEVMKELYDAGKIR 150 Query: 300 AIGVSNFSTKKLADLLAVA 356 AIGVSNFS +++ AVA Sbjct: 151 AIGVSNFSIEQMDTFRAVA 169
>YEAE_ECOLI (P76234) Hypothetical protein yeaE| Length = 284 Score = 50.1 bits (118), Expect = 3e-06 Identities = 48/157 (30%), Positives = 74/157 (47%), Gaps = 7/157 (4%) Frame = +3 Query: 24 KVLDEGVVK-REDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IHWPFQI 200 KV+ E + RE +F+ SK++ + + +A + +L L DYLDL+L +HW Sbjct: 62 KVVGEALTGLREKVFLVSKVYPWNAGGQKAINACEASLRRLNTDYLDLYL---LHW---- 114 Query: 201 KKGSELSPENFVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADLLAVARVPP---- 368 GS +T AMEKL GK R GVSN AD+ + ++P Sbjct: 115 -SGS---------FAFEETVAAMEKLIAQGKIRRWGVSNLD---YADMQELWQLPGGNQC 161 Query: 369 AVDQVECHPGWQ--QAKLRAFCRTNGVHFSAYAPLGR 473 A +QV H G + + L +C+ + AY+PL + Sbjct: 162 ATNQVLYHLGSRGIEYDLLPWCQQQQMPVMAYSPLAQ 198
>AFR_PIG (P82125) 1,5-anhydro-D-fructose reductase (EC 1.1.1.263) (AF| reductase) (Fragments) Length = 206 Score = 48.5 bits (114), Expect = 1e-05 Identities = 47/155 (30%), Positives = 60/155 (38%) Frame = +3 Query: 6 IGVALNKVLDEGVVKREDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IH 185 +GV + +DEGVV+REDLFI SK + YLDL IH Sbjct: 45 VGVGIQAKIDEGVVRREDLFIVSK----------------------KXXYLDL---XNIH 79 Query: 186 WPFQIKKGSELSPENFVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADLLAVARVP 365 WP Q K G E+D+P M I SN K Sbjct: 80 WPMQFKPG---------EVDLPVDRSGM-----------IVASNTDFKX----------- 108 Query: 366 PAVDQVECHPGWQQAKLRAFCRTNGVHFSAYAPLG 470 P +Q+E HP Q +F ++ V +AY PLG Sbjct: 109 PVTNQIESHPYLTQK--ISFXQSRNVSVTAYRPLG 141
>YDJG_ECOLI (P77256) Hypothetical oxidoreductase ydjG (EC 1.-.-.-)| Length = 326 Score = 45.4 bits (106), Expect = 8e-05 Identities = 39/166 (23%), Positives = 69/166 (41%), Gaps = 12/166 (7%) Frame = +3 Query: 6 IGVALNKVLDEGVV----------KREDLF--ITSKIWCSDLAPEDVPSAIDTTLNDLQL 149 +G AL K+ E VV ++ LF + + +L+PE + + +L L + Sbjct: 68 VGQALKKLPREQVVVETKCGIVWERKGSLFNKVGDRQLYKNLSPESIREEVAASLQRLGI 127 Query: 150 DYLDLHLVT*IHWPFQIKKGSELSPENFVELDMPQTWRAMEKLYDSGKARAIGVSNFSTK 329 DY+D+++ HW + P F + +T + +L GK RAIG +N Sbjct: 128 DYIDIYMT---HW--------QSVPPFFTPI--AETVAVLNELKSEGKIRAIGAANVDAD 174 Query: 330 KLADLLAVARVPPAVDQVECHPGWQQAKLRAFCRTNGVHFSAYAPL 467 + + L + + + +L CR NG+ Y+PL Sbjct: 175 HIREYLQYGELDIIQAKYSILDRAMENELLPLCRDNGIVVQVYSPL 220
>YAKC_SCHPO (Q09923) Aldo-keto reductase yakc [NADP+] (EC 1.1.1.-)| Length = 340 Score = 42.0 bits (97), Expect = 9e-04 Identities = 38/130 (29%), Positives = 57/130 (43%), Gaps = 5/130 (3%) Frame = +3 Query: 99 PEDVPSAIDTTLNDLQLDYLDLHLVT*IHWPFQIKKGSELSPENFVELDMPQTWRAMEKL 278 P+ + A+D +L L +D +DL+ V S E +E M A++K Sbjct: 101 PDYIEKALDLSLKRLGIDCIDLYYV------------HRFSGETPIEKIMG----ALKKC 144 Query: 279 YDSGKARAIGVSNFSTKKLADLLAVARVPPAVDQVECHPGWQQAK-----LRAFCRTNGV 443 ++GK R IG+S S + AV P + QVE P + + + CR N + Sbjct: 145 VEAGKIRYIGLSECSANTIRRAAAV--YPVSAVQVEYSPFSLEIERPEIGVMKACRENNI 202 Query: 444 HFSAYAPLGR 473 YAPLGR Sbjct: 203 TIVCYAPLGR 212
>IOLS_BACSU (P46336) Protein iolS (EC 1.1.1.-) (Vegetative protein 147)| (VEG147) (AKR11A) Length = 310 Score = 42.0 bits (97), Expect = 9e-04 Identities = 31/105 (29%), Positives = 54/105 (51%), Gaps = 8/105 (7%) Frame = +3 Query: 51 REDLFITSKI--------WCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IHWPFQIKK 206 RED+ I +K + D +P+ + ++D +L L DY+DL IH+P Sbjct: 76 REDVVIATKAAHRKQGNDFVFDNSPDFLKKSVDESLKRLNTDYIDLFY---IHFP----- 127 Query: 207 GSELSPENFVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLAD 341 E +P++ + A+ ++ +GK R+IGVSNFS ++L + Sbjct: 128 -DEHTPKD-------EAVNALNEMKKAGKIRSIGVSNFSLEQLKE 164
>YCCK_BACSU (P46905) Hypothetical oxidoreductase yccK (EC 1.-.-.-)| Length = 310 Score = 40.0 bits (92), Expect = 0.003 Identities = 32/126 (25%), Positives = 56/126 (44%) Frame = +3 Query: 90 DLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IHWPFQIKKGSELSPENFVELDMPQTWRAM 269 D + E + S ++ +L L+ DY+DL+ V H+P +E++ + Sbjct: 99 DNSREFLRSEVEKSLKRLKTDYIDLYYV---HFPDGKTPLAEVAG-------------TL 142 Query: 270 EKLYDSGKARAIGVSNFSTKKLADLLAVARVPPAVDQVECHPGWQQAKLRAFCRTNGVHF 449 ++L D GK +AIG SN ++L D A + + + +L +C G+ F Sbjct: 143 KELKDEGKIKAIGASNLDYQQLQDFNADGYLEVFQAEYSLIQRDAEKELLPYCEKQGISF 202 Query: 450 SAYAPL 467 Y PL Sbjct: 203 IPYFPL 208
>KCAB2_XENLA (Q9PTM5) Voltage-gated potassium channel beta-2 subunit (K(+)| channel beta-2 subunit) (Kv-beta-2) Length = 367 Score = 39.7 bits (91), Expect = 0.004 Identities = 35/138 (25%), Positives = 60/138 (43%), Gaps = 11/138 (7%) Frame = +3 Query: 12 VALNKVLDEGVVKREDLFITSKIWCSD-------LAPEDVPSAIDTTLNDLQLDYLDLHL 170 V L ++ + +R L IT+KI+ L+ + + + +L LQLDY+D+ Sbjct: 97 VVLGNIIKKKGWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLDYVDVVF 156 Query: 171 VT*IHWPFQIKKGSELSPENFVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADLLA 350 P+ M +T RAM + + G A G S +S+ ++ + + Sbjct: 157 AN--------------RPDP--NTPMEETVRAMTHVINQGMAMYWGTSRWSSMEIMEAYS 200 Query: 351 VAR----VPPAVDQVECH 392 VAR +PP +Q E H Sbjct: 201 VARQFNLIPPICEQAEYH 218
>KCAB1_CHICK (Q9PWR1) Voltage-gated potassium channel beta-1 subunit (K(+)| channel beta-1 subunit) (Kv-beta-1) Length = 401 Score = 38.5 bits (88), Expect = 0.010 Identities = 34/138 (24%), Positives = 59/138 (42%), Gaps = 11/138 (7%) Frame = +3 Query: 12 VALNKVLDEGVVKREDLFITSKIWCSD-------LAPEDVPSAIDTTLNDLQLDYLDLHL 170 V L +L + +R L IT+K++ L+ + + + +L LQL+Y+D+ Sbjct: 131 VILGNILKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLRASLQRLQLEYVDVVF 190 Query: 171 VT*IHWPFQIKKGSELSPENFVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADLLA 350 P+N M + RAM + + G A G S +S ++ + + Sbjct: 191 AN--------------RPDN--NTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIMEAYS 234 Query: 351 VAR----VPPAVDQVECH 392 VAR +PP +Q E H Sbjct: 235 VARQFNLIPPVCEQAEYH 252
>KCAB2_RAT (P62483) Voltage-gated potassium channel beta-2 subunit (K(+)| channel beta-2 subunit) (Kv-beta-2) Length = 367 Score = 38.1 bits (87), Expect = 0.013 Identities = 34/138 (24%), Positives = 60/138 (43%), Gaps = 11/138 (7%) Frame = +3 Query: 12 VALNKVLDEGVVKREDLFITSKIWCSD-------LAPEDVPSAIDTTLNDLQLDYLDLHL 170 V L ++ + +R L IT+KI+ L+ + + + +L LQL+Y+D+ Sbjct: 97 VVLGNIIKKKGWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVF 156 Query: 171 VT*IHWPFQIKKGSELSPENFVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADLLA 350 P+ M +T RAM + + G A G S +S+ ++ + + Sbjct: 157 AN--------------RPDP--NTPMEETVRAMTHVINQGMAMYWGTSRWSSMEIMEAYS 200 Query: 351 VAR----VPPAVDQVECH 392 VAR +PP +Q E H Sbjct: 201 VARQFNLIPPICEQAEYH 218
>KCAB2_MOUSE (P62482) Voltage-gated potassium channel beta-2 subunit (K(+)| channel beta-2 subunit) (Kv-beta-2) (Neuroimmune protein F5) Length = 367 Score = 38.1 bits (87), Expect = 0.013 Identities = 34/138 (24%), Positives = 60/138 (43%), Gaps = 11/138 (7%) Frame = +3 Query: 12 VALNKVLDEGVVKREDLFITSKIWCSD-------LAPEDVPSAIDTTLNDLQLDYLDLHL 170 V L ++ + +R L IT+KI+ L+ + + + +L LQL+Y+D+ Sbjct: 97 VVLGNIIKKKGWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVF 156 Query: 171 VT*IHWPFQIKKGSELSPENFVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADLLA 350 P+ M +T RAM + + G A G S +S+ ++ + + Sbjct: 157 AN--------------RPDP--NTPMEETVRAMTHVINQGMAMYWGTSRWSSMEIMEAYS 200 Query: 351 VAR----VPPAVDQVECH 392 VAR +PP +Q E H Sbjct: 201 VARQFNLIPPICEQAEYH 218
>KCAB2_BOVIN (Q27955) Voltage-gated potassium channel beta-2 subunit (K(+)| channel beta-2 subunit) (Kv-beta-2) Length = 367 Score = 38.1 bits (87), Expect = 0.013 Identities = 34/138 (24%), Positives = 60/138 (43%), Gaps = 11/138 (7%) Frame = +3 Query: 12 VALNKVLDEGVVKREDLFITSKIWCSD-------LAPEDVPSAIDTTLNDLQLDYLDLHL 170 V L ++ + +R L IT+KI+ L+ + + + +L LQL+Y+D+ Sbjct: 97 VVLGNIIKKKGWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVF 156 Query: 171 VT*IHWPFQIKKGSELSPENFVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADLLA 350 P+ M +T RAM + + G A G S +S+ ++ + + Sbjct: 157 AN--------------RPDP--NTPMEETVRAMTHVINQGMAMYWGTSRWSSMEIMEAYS 200 Query: 351 VAR----VPPAVDQVECH 392 VAR +PP +Q E H Sbjct: 201 VARQFNLIPPICEQAEYH 218
>CROB_LEPLU (P49261) Rho beta-crystallin (Fragments)| Length = 89 Score = 37.7 bits (86), Expect = 0.017 Identities = 25/68 (36%), Positives = 37/68 (54%), Gaps = 1/68 (1%) Frame = +3 Query: 141 LQLDYLDLHLVT*IHWPFQIKKGSELSPENFVELDMPQTWRAMEKLYDSGKARAIG-VSN 317 ++LDYLDL+L IH+P G ++ P N D+ TW ME L D+G + + + Sbjct: 20 IKLDYLDLYL---IHFPM----GFKVIPSN---TDIRDTWEGMEDLVDAGLVKYTSLIED 69 Query: 318 FSTKKLAD 341 KK+AD Sbjct: 70 PXVKKIAD 77
>KCAB3_XENLA (Q9PTM4) Voltage-gated potassium channel beta-3 subunit (K(+)| channel beta-3 subunit) (Kv-beta-3) Length = 401 Score = 37.7 bits (86), Expect = 0.017 Identities = 33/136 (24%), Positives = 59/136 (43%), Gaps = 11/136 (8%) Frame = +3 Query: 18 LNKVLDEGVVKREDLFITSKIWCSD-------LAPEDVPSAIDTTLNDLQLDYLDLHLVT 176 L K+L + +R +T+KI+ L+ + + + +L LQLDY+D+ Sbjct: 133 LGKILKKKEWRRSSYVVTTKIYWGGQAETERGLSRKHIIEGLRGSLERLQLDYVDIVFA- 191 Query: 177 *IHWPFQIKKGSELSPENFVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADLLAVA 356 + + P + M + RAM + + G A G S +S ++ + +VA Sbjct: 192 -----------NRMDPNS----PMEEIVRAMTFVINQGMAMYWGTSRWSAMEIMEAYSVA 236 Query: 357 R----VPPAVDQVECH 392 R +PP +Q E H Sbjct: 237 RQFNLIPPVCEQAEYH 252
>KCAB2_HUMAN (Q13303) Voltage-gated potassium channel beta-2 subunit (K(+)| channel beta-2 subunit) (Kv-beta-2) (HKvbeta2) Length = 367 Score = 37.0 bits (84), Expect = 0.029 Identities = 34/138 (24%), Positives = 59/138 (42%), Gaps = 11/138 (7%) Frame = +3 Query: 12 VALNKVLDEGVVKREDLFITSKIWCSD-------LAPEDVPSAIDTTLNDLQLDYLDLHL 170 V L ++ + +R L IT+KI+ L+ + + + +L LQL+Y+D+ Sbjct: 97 VVLGNIIKKKGWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVF 156 Query: 171 VT*IHWPFQIKKGSELSPENFVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADLLA 350 P+ M +T RAM + + G A G S +S+ ++ + + Sbjct: 157 AN--------------RPDP--NTPMEETVRAMTHVINQGMAMYWGTSRWSSMEIMEAYS 200 Query: 351 VAR----VPPAVDQVECH 392 VAR PP +Q E H Sbjct: 201 VARQFNLTPPICEQAEYH 218
>KCAB1_RAT (P63144) Voltage-gated potassium channel beta-1 subunit (K(+)| channel beta-1 subunit) (Kv-beta-1) Length = 401 Score = 36.6 bits (83), Expect = 0.038 Identities = 34/138 (24%), Positives = 59/138 (42%), Gaps = 11/138 (7%) Frame = +3 Query: 12 VALNKVLDEGVVKREDLFITSKIWCSD-------LAPEDVPSAIDTTLNDLQLDYLDLHL 170 V L ++ + +R L IT+K++ L+ + + + +L LQL+Y+D+ Sbjct: 131 VILGSIIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDV-- 188 Query: 171 VT*IHWPFQIKKGSELSPENFVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADLLA 350 F + S E V RAM + + G A G S +S ++ + + Sbjct: 189 ------VFANRPDSNTPMEEIV--------RAMTHVINQGMAMYWGTSRWSAMEIMEAYS 234 Query: 351 VAR----VPPAVDQVECH 392 VAR +PP +Q E H Sbjct: 235 VARQFNMIPPVCEQAEYH 252
>KCAB1_MOUSE (P63143) Voltage-gated potassium channel beta-1 subunit (K(+)| channel beta-1 subunit) (Kv-beta-1) Length = 401 Score = 36.6 bits (83), Expect = 0.038 Identities = 34/138 (24%), Positives = 59/138 (42%), Gaps = 11/138 (7%) Frame = +3 Query: 12 VALNKVLDEGVVKREDLFITSKIWCSD-------LAPEDVPSAIDTTLNDLQLDYLDLHL 170 V L ++ + +R L IT+K++ L+ + + + +L LQL+Y+D+ Sbjct: 131 VILGSIIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDV-- 188 Query: 171 VT*IHWPFQIKKGSELSPENFVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADLLA 350 F + S E V RAM + + G A G S +S ++ + + Sbjct: 189 ------VFANRPDSNTPMEEIV--------RAMTHVINQGMAMYWGTSRWSAMEIMEAYS 234 Query: 351 VAR----VPPAVDQVECH 392 VAR +PP +Q E H Sbjct: 235 VARQFNMIPPVCEQAEYH 252
>KCAB1_BOVIN (Q4PJK1) Voltage-gated potassium channel beta-1 subunit (K(+)| channel beta-1 subunit) (Kv-beta-1) Length = 401 Score = 36.6 bits (83), Expect = 0.038 Identities = 34/138 (24%), Positives = 59/138 (42%), Gaps = 11/138 (7%) Frame = +3 Query: 12 VALNKVLDEGVVKREDLFITSKIWCSD-------LAPEDVPSAIDTTLNDLQLDYLDLHL 170 V L ++ + +R L IT+K++ L+ + + + +L LQL+Y+D+ Sbjct: 131 VILGSIIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDV-- 188 Query: 171 VT*IHWPFQIKKGSELSPENFVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADLLA 350 F + S E V RAM + + G A G S +S ++ + + Sbjct: 189 ------VFANRPDSNTPMEEIV--------RAMTHVINQGMAMYWGTSRWSAMEIMEAYS 234 Query: 351 VAR----VPPAVDQVECH 392 VAR +PP +Q E H Sbjct: 235 VARQFNMIPPVCEQAEYH 252
>KCAB1_RABIT (Q9XT31) Voltage-gated potassium channel beta-1 subunit (K(+)| channel beta-1 subunit) (Kv-beta-1) Length = 419 Score = 36.6 bits (83), Expect = 0.038 Identities = 34/138 (24%), Positives = 59/138 (42%), Gaps = 11/138 (7%) Frame = +3 Query: 12 VALNKVLDEGVVKREDLFITSKIWCSD-------LAPEDVPSAIDTTLNDLQLDYLDLHL 170 V L ++ + +R L IT+K++ L+ + + + +L LQL+Y+D+ Sbjct: 149 VILGSIIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDV-- 206 Query: 171 VT*IHWPFQIKKGSELSPENFVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADLLA 350 F + S E V RAM + + G A G S +S ++ + + Sbjct: 207 ------VFANRPDSNTPMEEIV--------RAMTHVINQGMAMYWGTSRWSAMEIMEAYS 252 Query: 351 VAR----VPPAVDQVECH 392 VAR +PP +Q E H Sbjct: 253 VARQFNMIPPVCEQAEYH 270
>KCAB1_HUMAN (Q14722) Voltage-gated potassium channel beta-1 subunit (K(+)| channel beta-1 subunit) (Kv-beta-1) Length = 419 Score = 36.6 bits (83), Expect = 0.038 Identities = 34/138 (24%), Positives = 59/138 (42%), Gaps = 11/138 (7%) Frame = +3 Query: 12 VALNKVLDEGVVKREDLFITSKIWCSD-------LAPEDVPSAIDTTLNDLQLDYLDLHL 170 V L ++ + +R L IT+K++ L+ + + + +L LQL+Y+D+ Sbjct: 149 VILGSIIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDV-- 206 Query: 171 VT*IHWPFQIKKGSELSPENFVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADLLA 350 F + S E V RAM + + G A G S +S ++ + + Sbjct: 207 ------VFANRPDSNTPMEEIV--------RAMTHVINQGMAMYWGTSRWSAMEIMEAYS 252 Query: 351 VAR----VPPAVDQVECH 392 VAR +PP +Q E H Sbjct: 253 VARQFNMIPPVCEQAEYH 270
>KCAB1_MUSPU (Q28528) Voltage-gated potassium channel beta-1 subunit (K(+)| channel beta-1 subunit) (Kv-beta-1) Length = 408 Score = 36.6 bits (83), Expect = 0.038 Identities = 34/138 (24%), Positives = 59/138 (42%), Gaps = 11/138 (7%) Frame = +3 Query: 12 VALNKVLDEGVVKREDLFITSKIWCSD-------LAPEDVPSAIDTTLNDLQLDYLDLHL 170 V L ++ + +R L IT+K++ L+ + + + +L LQL+Y+D+ Sbjct: 138 VILGSIIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDV-- 195 Query: 171 VT*IHWPFQIKKGSELSPENFVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADLLA 350 F + S E V RAM + + G A G S +S ++ + + Sbjct: 196 ------VFANRPDSNTPMEEIV--------RAMTHVINQGMAMYWGTSRWSAMEIMEAYS 241 Query: 351 VAR----VPPAVDQVECH 392 VAR +PP +Q E H Sbjct: 242 VARQFNMIPPVCEQAEYH 259
>YDHF_ECOLI (P76187) Oxidoreductase ydhF (EC 1.-.-.-)| Length = 298 Score = 35.4 bits (80), Expect = 0.084 Identities = 29/98 (29%), Positives = 45/98 (45%) Frame = +3 Query: 102 EDVPSAIDTTLNDLQLDYLDLHLVT*IHWPFQIKKGSELSPENFVELDMPQTWRAMEKLY 281 + + + + +L +L D+LDL L IH P + E++ A + L+ Sbjct: 104 DHIIKSAEQSLINLATDHLDLLL---IHRPDPLMDADEVAD-------------AFKHLH 147 Query: 282 DSGKARAIGVSNFSTKKLADLLAVARVPPAVDQVECHP 395 SGK R GVSNF+ + A L + A +QVE P Sbjct: 148 QSGKVRHFGVSNFTPAQFALLQSRLPFTLATNQVEISP 185
>YGHZ_ECOLI (Q46851) Hypothetical protein yghZ| Length = 346 Score = 35.0 bits (79), Expect = 0.11 Identities = 32/126 (25%), Positives = 60/126 (47%), Gaps = 6/126 (4%) Frame = +3 Query: 114 SAIDTTLNDLQLDYLDLHLVT*IHWPFQIKKGSELSPENFVELDMPQTWRAMEKLYDSGK 293 +++D +L + L+Y+D+ F + E +P M +T A+ SGK Sbjct: 118 ASLDQSLKRMGLEYVDI---------FYSHRVDENTP-------MEETASALAHAVQSGK 161 Query: 294 ARAIGVSNFS---TKKLADLLAVARVPPAVDQVECH--PGW-QQAKLRAFCRTNGVHFSA 455 A +G+S++S T+K+ +LL ++P + Q + W ++ L + NGV A Sbjct: 162 ALYVGISSYSPERTQKMVELLREWKIPLLIHQPSYNLLNRWVDKSGLLDTLQNNGVGCIA 221 Query: 456 YAPLGR 473 + PL + Sbjct: 222 FTPLAQ 227
>YGHZ_ECO57 (Q8X529) Hypothetical protein yghZ| Length = 346 Score = 34.7 bits (78), Expect = 0.14 Identities = 32/126 (25%), Positives = 60/126 (47%), Gaps = 6/126 (4%) Frame = +3 Query: 114 SAIDTTLNDLQLDYLDLHLVT*IHWPFQIKKGSELSPENFVELDMPQTWRAMEKLYDSGK 293 +++D +L + L+Y+D+ F + E +P M +T A+ SGK Sbjct: 118 ASLDQSLKRMGLEYVDI---------FYSHRVDENTP-------MEETASALAHAVQSGK 161 Query: 294 ARAIGVSNFS---TKKLADLLAVARVPPAVDQVECH--PGW-QQAKLRAFCRTNGVHFSA 455 A +G+S++S T+K+ +LL ++P + Q + W ++ L + NGV A Sbjct: 162 ALYVGISSYSPERTQKMVELLHEWKIPLLIHQPSYNLLNRWVDKSGLLDTLQNNGVGCIA 221 Query: 456 YAPLGR 473 + PL + Sbjct: 222 FTPLAQ 227
>TAS_SHIFL (P0A9T5) Protein tas| Length = 346 Score = 33.1 bits (74), Expect = 0.42 Identities = 24/76 (31%), Positives = 38/76 (50%), Gaps = 4/76 (5%) Frame = +3 Query: 102 EDVPSAIDTTLNDLQLDYLDLHLVT*IHWPFQ----IKKGSELSPENFVELDMPQTWRAM 269 +++ A+ +L LQ DYLDL+ V HWP + K ++ + + T A+ Sbjct: 108 KNIREALHDSLKRLQTDYLDLYQV---HWPQRPTNCFGKLGYSWTDSAPAVSLLDTLDAL 164 Query: 270 EKLYDSGKARAIGVSN 317 + +GK R IGVSN Sbjct: 165 AEYQRAGKIRYIGVSN 180
>TAS_ECOLI (P0A9T4) Protein tas| Length = 346 Score = 33.1 bits (74), Expect = 0.42 Identities = 24/76 (31%), Positives = 38/76 (50%), Gaps = 4/76 (5%) Frame = +3 Query: 102 EDVPSAIDTTLNDLQLDYLDLHLVT*IHWPFQ----IKKGSELSPENFVELDMPQTWRAM 269 +++ A+ +L LQ DYLDL+ V HWP + K ++ + + T A+ Sbjct: 108 KNIREALHDSLKRLQTDYLDLYQV---HWPQRPTNCFGKLGYSWTDSAPAVSLLDTLDAL 164 Query: 270 EKLYDSGKARAIGVSN 317 + +GK R IGVSN Sbjct: 165 AEYQRAGKIRYIGVSN 180
>A115_TOBAC (P40691) Auxin-induced protein PCNT115| Length = 307 Score = 32.0 bits (71), Expect = 0.93 Identities = 29/125 (23%), Positives = 56/125 (44%) Frame = +3 Query: 99 PEDVPSAIDTTLNDLQLDYLDLHLVT*IHWPFQIKKGSELSPENFVELDMPQTWRAMEKL 278 P V +A + +L L +D +DL+ +Q + + + +E+ + + ++KL Sbjct: 111 PAYVRAACEASLKRLDIDCIDLY--------YQHRVDTRVP----IEITVGE----LKKL 154 Query: 279 YDSGKARAIGVSNFSTKKLADLLAVARVPPAVDQVECHPGWQQAKLRAFCRTNGVHFSAY 458 + GK + IG+S S + AV + + + ++ CR G+ AY Sbjct: 155 VEEGKLKYIGLSEASASTIRRAHAVHPITAVQLEWSLWSRDVEEEIIPTCRELGIGIVAY 214 Query: 459 APLGR 473 +PLGR Sbjct: 215 SPLGR 219
>YCSN_BACSU (P42972) Hypothetical oxidoreductase ycsN (EC 1.-.-.-)| Length = 300 Score = 32.0 bits (71), Expect = 0.93 Identities = 33/129 (25%), Positives = 55/129 (42%), Gaps = 3/129 (2%) Frame = +3 Query: 114 SAIDTTLNDLQLDYLDLHLVT*IHWPFQIKKGSELSPENFVELDMPQTWRAMEKLYDSGK 293 ++++ +L +L+ DY+D+ L IH P + + PE E A + L SGK Sbjct: 108 ASVEQSLMNLRTDYIDMLL---IHRPDPL-----MDPEGVAE--------AFQALKCSGK 151 Query: 294 ARAIGVSNFSTKKLADLLAVARVPPAVDQVECHPGWQQAKLRA---FCRTNGVHFSAYAP 464 R GVSNF + L + +Q+E + L C+ + A++P Sbjct: 152 VRYFGVSNFKDHQYRMLESYLPEKLVTNQIELSAYELENMLDGTLNLCQEKRIPPMAWSP 211 Query: 465 LGRMKVVAD 491 L KV + Sbjct: 212 LAGGKVFTE 220
>Y215_ADE02 (P03291) Hypothetical protein F-215| Length = 215 Score = 31.6 bits (70), Expect = 1.2 Identities = 14/49 (28%), Positives = 23/49 (46%) Frame = -1 Query: 414 AWPAANQGGTPPDQRPEEHGPQRADRPASWSKNCLRLLREPCLNRTASP 268 +WPA+ PP P+ +R +SW K+ ++ +E C A P Sbjct: 23 SWPASPTTSPPPWSEPDAEISRRKRSSSSWPKSPIKTTQETCRRFCARP 71
>ALKE_BABBO (P40690) Aldo-keto reductase (Fragment)| Length = 285 Score = 31.2 bits (69), Expect = 1.6 Identities = 40/147 (27%), Positives = 62/147 (42%), Gaps = 22/147 (14%) Frame = +3 Query: 93 LAPEDVPSAIDTTLNDLQLDYLDLHLVT*IHWPFQ-------------IKKGSELSPENF 233 L+ +++ A+D +L+ L DY+DL +HWP + + EN Sbjct: 26 LSKDNILKAVDGSLSRLNTDYIDL---LQLHWPDRYVPMNANGDFHEVFHDTENMIDENS 82 Query: 234 VELDMPQTWRAMEKLYDSGKARAIGVSN---FSTKKLADLLAVARV-PPAVDQVECHPGW 401 V L+ A++ L GK R G+SN + T + L A V PA Q+ + Sbjct: 83 VPLE--DQLDALQTLLTQGKIRHWGLSNETPWGTLRFYKLAKQAGVAAPASVQLHYNLLC 140 Query: 402 QQAKLRAF---CR--TNGVHFSAYAPL 467 + + F CR G+ AYAPL Sbjct: 141 RNEVEKGFVELCRPQNTGIAILAYAPL 167
>KCAB3_MOUSE (P97382) Voltage-gated potassium channel beta-3 subunit (K(+)| channel beta-3 subunit) (Kv-beta-3) Length = 249 Score = 31.2 bits (69), Expect = 1.6 Identities = 25/98 (25%), Positives = 43/98 (43%), Gaps = 4/98 (4%) Frame = +3 Query: 111 PSAIDTTLNDLQLDYLDLHLVT*IHWPFQIKKGSELSPENFVELDMPQTWRAMEKLYDSG 290 P + +L+ LQL+Y+D+ + SP M + RAM + + G Sbjct: 23 PPGLQGSLDRLQLEYVDIVFA---------NRSDPNSP-------MEEIVRAMTYVINQG 66 Query: 291 KARAIGVSNFSTKKLADLLAVAR----VPPAVDQVECH 392 A G S +S ++ + ++AR +PP +Q E H Sbjct: 67 LALYWGTSRWSAAEIMEAYSMARQFNLIPPVCEQAENH 104
>ZEP1_HUMAN (P15822) Zinc finger protein 40 (Human immunodeficiency virus type I| enhancer-binding protein 1) (HIV-EP1) (Major histocompatibility complex-binding protein 1) (MBP-1) (Positive regulatory domain II-binding factor 1) (PRDII-BF1) Length = 2717 Score = 30.8 bits (68), Expect = 2.1 Identities = 15/31 (48%), Positives = 23/31 (74%) Frame = -2 Query: 440 SIGAAEGSELGLLPTRVALHLINGRRNTGHS 348 ++ A+ + LGL PT+VAL L+N ++NTG S Sbjct: 1968 TVSASNPNPLGL-PTKVALALLNSKQNTGKS 1997
>IN22_MAIZE (P49249) IN2-2 protein| Length = 306 Score = 30.0 bits (66), Expect = 3.5 Identities = 19/69 (27%), Positives = 31/69 (44%) Frame = +3 Query: 267 MEKLYDSGKARAIGVSNFSTKKLADLLAVARVPPAVDQVECHPGWQQAKLRAFCRTNGVH 446 ++KL + GK + IG+S S + AV + + + + CR G+ Sbjct: 146 LKKLVEEGKIKYIGLSEASASTIRRAHAVHPITAVQLEWSLWSRDAEEDIIPTCRELGIG 205 Query: 447 FSAYAPLGR 473 AY+PLGR Sbjct: 206 IVAYSPLGR 214
>PHP_DROME (P39769) Polyhomeotic-proximal chromatin protein| Length = 1589 Score = 30.0 bits (66), Expect = 3.5 Identities = 17/57 (29%), Positives = 27/57 (47%), Gaps = 3/57 (5%) Frame = -1 Query: 408 PAANQGGTPPDQRPEEHGPQRADRPASWS---KNCLRLLREPCLNRTASPLPARSGA 247 P +++ GTPP R + H P +RP++ S NC + R L + P + A Sbjct: 138 PTSHRHGTPPTGRRQTHTPSTPNRPSAPSTPNTNCNSIARHTSLTLEKAQNPGQQVA 194
>DNB2_ADE07 (P04497) Early E2A DNA-binding protein| Length = 517 Score = 29.6 bits (65), Expect = 4.6 Identities = 25/86 (29%), Positives = 36/86 (41%), Gaps = 1/86 (1%) Frame = -1 Query: 402 ANQGGTPPDQRPEEHGPQRADRPASWSKNCLRLLREPCLNRTASPLPARSGAY-RARQNS 226 A++GG R EH P+R AS R R P +++ PLP + Y R NS Sbjct: 2 ASRGGNQSSDRQREHTPERGMGSASHPPP--RPDRSP--SQSPPPLPPKRNTYRRVGSNS 57 Query: 225 QGSAHCLSLSERASESKLPGAGQDNP 148 + + +SE + S P P Sbjct: 58 SIESQVVLVSETSRSSLSPERSNSPP 83
>ARK72_RAT (Q8CG45) Aflatoxin B1 aldehyde reductase member 2 (EC 1.-.-.-)| (rAFAR2) Length = 367 Score = 29.6 bits (65), Expect = 4.6 Identities = 25/116 (21%), Positives = 48/116 (41%) Frame = +3 Query: 93 LAPEDVPSAIDTTLNDLQLDYLDLHLVT*IHWPFQIKKGSELSPENFVELDMPQTWRAME 272 L P+ V S ++T+L LQ +DL F + +P + +T +A + Sbjct: 122 LKPDSVRSQLETSLKRLQCPRVDL---------FYLHAPDHGTP-------IVETLQACQ 165 Query: 273 KLYDSGKARAIGVSNFSTKKLADLLAVARVPPAVDQVECHPGWQQAKLRAFCRTNG 440 +L+ GK +G+SN+++ W+ A++ C++NG Sbjct: 166 QLHQEGKFVELGLSNYAS------------------------WEVAEIYTLCKSNG 197
>KCNV2_HUMAN (Q8TDN2) Potassium voltage-gated channel subfamily V member 2| (Voltage-gated potassium channel subunit Kv8.2) Length = 545 Score = 29.3 bits (64), Expect = 6.0 Identities = 22/69 (31%), Positives = 38/69 (55%), Gaps = 1/69 (1%) Frame = +3 Query: 195 QIKKGSELSPE-NFVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADLLAVARVPPA 371 Q+++ EL + F + W MEK + S A+AIGV++ ST L ++A+A Sbjct: 225 QVEEAEELFRDMRFYGPQRRRLWNLMEKPFSSVAAKAIGVAS-STFVLVSVVALAL--NT 281 Query: 372 VDQVECHPG 398 V++++ H G Sbjct: 282 VEEMQQHSG 290
>Y2320_MYCBO (P63485) Hypothetical protein Mb2320| Length = 323 Score = 29.3 bits (64), Expect = 6.0 Identities = 36/144 (25%), Positives = 55/144 (38%), Gaps = 3/144 (2%) Frame = +3 Query: 51 REDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IHWPFQIKKGSELSPEN 230 R ++ + SK++ P + + + LQL+ + L+ IH P + S + P Sbjct: 76 RTEVVVASKVFPVAPFPAVIKNRERASARRLQLNRIPLYQ---IHQPNPVVPDSVIMP-- 130 Query: 231 FVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADLLAVARVPPAVDQVE---CHPGW 401 M L DSG A GVSN+S + A P +QV HP Sbjct: 131 -----------GMRDLLDSGDIGAAGVSNYSLARWRKADAALGRPVVSNQVHFSLAHPDA 179 Query: 402 QQAKLRAFCRTNGVHFSAYAPLGR 473 + L F AY+PL + Sbjct: 180 LE-DLVPFAELENRIVIAYSPLAQ 202
>Y2298_MYCTU (P63484) Hypothetical protein Rv2298/MT2355| Length = 323 Score = 29.3 bits (64), Expect = 6.0 Identities = 36/144 (25%), Positives = 55/144 (38%), Gaps = 3/144 (2%) Frame = +3 Query: 51 REDLFITSKIWCSDLAPEDVPSAIDTTLNDLQLDYLDLHLVT*IHWPFQIKKGSELSPEN 230 R ++ + SK++ P + + + LQL+ + L+ IH P + S + P Sbjct: 76 RTEVVVASKVFPVAPFPAVIKNRERASARRLQLNRIPLYQ---IHQPNPVVPDSVIMP-- 130 Query: 231 FVELDMPQTWRAMEKLYDSGKARAIGVSNFSTKKLADLLAVARVPPAVDQVE---CHPGW 401 M L DSG A GVSN+S + A P +QV HP Sbjct: 131 -----------GMRDLLDSGDIGAAGVSNYSLARWRKADAALGRPVVSNQVHFSLAHPDA 179 Query: 402 QQAKLRAFCRTNGVHFSAYAPLGR 473 + L F AY+PL + Sbjct: 180 LE-DLVPFAELENRIVIAYSPLAQ 202
>VGF_HUMAN (O15240) Neurosecretory protein VGF precursor| Length = 616 Score = 29.3 bits (64), Expect = 6.0 Identities = 19/49 (38%), Positives = 27/49 (55%) Frame = -1 Query: 288 LNRTASPLPARSGAYRARQNSQGSAHCLSLSERASESKLPGAGQDNPAA 142 L+R ASP PA SG+ + + A L+ + R+ LP AG+ PAA Sbjct: 90 LDRPASP-PAPSGSQQGPEEEAAEA-LLTETVRSQTHSLPAAGEPEPAA 136
>ELOA2_HUMAN (Q8IYF1) RNA polymerase II transcription factor SIII subunit A2| (Elongin A2) (EloA2) (Transcription elongation factor B polypeptide 3B) Length = 753 Score = 29.3 bits (64), Expect = 6.0 Identities = 26/93 (27%), Positives = 30/93 (32%), Gaps = 3/93 (3%) Frame = -1 Query: 414 AWPAANQGGTP--PDQRPEEHGPQRADRPASWSKNCLRLLREPCLNRTASPL-PARSGAY 244 AW P P PE R P + REP R + PA SG Y Sbjct: 109 AWGFPENATAPRSPSHSPEHRRTARRTPPGQQRPHPRSHSREPRAERKCPRIAPADSGRY 168 Query: 243 RARQNSQGSAHCLSLSERASESKLPGAGQDNPA 145 RA E A+ K PG G + A Sbjct: 169 RASPTRTAPLRMPEGPEPAAPGKQPGRGHTHAA 201
>NBN_MOUSE (Q9R207) Nibrin (Nijmegen breakage syndrome protein 1 homolog)| (Cell cycle regulatory protein p95) Length = 751 Score = 28.9 bits (63), Expect = 7.8 Identities = 14/38 (36%), Positives = 19/38 (50%) Frame = -1 Query: 264 PARSGAYRARQNSQGSAHCLSLSERASESKLPGAGQDN 151 P Y A S+ + C+ LSER E K+PG Q + Sbjct: 357 PVNMTTYVADTESEPADTCMPLSERPEEVKIPGLEQSS 394 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 68,072,887 Number of Sequences: 219361 Number of extensions: 1357480 Number of successful extensions: 4613 Number of sequences better than 10.0: 123 Number of HSP's better than 10.0 without gapping: 4315 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4456 length of database: 80,573,946 effective HSP length: 103 effective length of database: 57,979,763 effective search space used: 3478785780 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
