ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | basd20j23 |
|---|---|
| Clone Library Name | barley_pub |
>MSK3_MEDSA (P51139) Glycogen synthase kinase-3 homolog MsK-3 (EC 2.7.11.1)| Length = 411 Score = 301 bits (770), Expect = 7e-82 Identities = 142/150 (94%), Positives = 146/150 (97%) Frame = +1 Query: 4 MRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKLY 183 MRLLDHPNVVSLKHCFFSTTEKDEL+LNLVLEYVPETV RVIRHYNKMNQRMP+IYVKLY Sbjct: 119 MRLLDHPNVVSLKHCFFSTTEKDELYLNLVLEYVPETVSRVIRHYNKMNQRMPMIYVKLY 178 Query: 184 SYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYICSR 363 SYQIC ALAYIH ++GVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYICSR Sbjct: 179 SYQICRALAYIHNSIGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYICSR 238 Query: 364 YYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 YYRAPELIFGATEYTTAIDIWSAGCVL EL Sbjct: 239 YYRAPELIFGATEYTTAIDIWSAGCVLGEL 268
>KSG1_ARATH (P43288) Shaggy-related protein kinase alpha (EC 2.7.11.1)| (ASK-alpha) Length = 405 Score = 296 bits (759), Expect = 1e-80 Identities = 138/150 (92%), Positives = 147/150 (98%) Frame = +1 Query: 4 MRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKLY 183 MRLLDHPNVVSLKHCFFSTTEKDEL+LNLVLEYVPETVHRVI+HYNK+NQRMPLIYVKLY Sbjct: 114 MRLLDHPNVVSLKHCFFSTTEKDELYLNLVLEYVPETVHRVIKHYNKLNQRMPLIYVKLY 173 Query: 184 SYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYICSR 363 +YQI AL+YIHR +GVCHRDIKPQNLLVNPHTHQ+K+CDFGSAKVLVKGEPNISYICSR Sbjct: 174 TYQIFRALSYIHRCIGVCHRDIKPQNLLVNPHTHQVKLCDFGSAKVLVKGEPNISYICSR 233 Query: 364 YYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 YYRAPELIFGATEYTTAID+WSAGCVLAEL Sbjct: 234 YYRAPELIFGATEYTTAIDVWSAGCVLAEL 263
>KSG3_ARATH (P43289) Shaggy-related protein kinase gamma (EC 2.7.11.1)| (ASK-gamma) Length = 409 Score = 295 bits (755), Expect = 4e-80 Identities = 136/150 (90%), Positives = 147/150 (98%) Frame = +1 Query: 4 MRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKLY 183 MRLLDHPNVVSLKHCFFSTTEKDEL+LNLVLEYVPETVHRVI+HYNK+NQRMPL+YVKLY Sbjct: 118 MRLLDHPNVVSLKHCFFSTTEKDELYLNLVLEYVPETVHRVIKHYNKLNQRMPLVYVKLY 177 Query: 184 SYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYICSR 363 +YQI +L+YIHR +GVCHRDIKPQNLLVNPHTHQ+K+CDFGSAKVLVKGEPNISYICSR Sbjct: 178 TYQIFRSLSYIHRCIGVCHRDIKPQNLLVNPHTHQVKLCDFGSAKVLVKGEPNISYICSR 237 Query: 364 YYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 YYRAPELIFGATEYTTAID+WSAGCVLAEL Sbjct: 238 YYRAPELIFGATEYTTAIDVWSAGCVLAEL 267
>MSK2_MEDSA (P51138) Glycogen synthase kinase-3 homolog MsK-2 (EC 2.7.11.1)| Length = 411 Score = 293 bits (749), Expect = 2e-79 Identities = 138/150 (92%), Positives = 145/150 (96%) Frame = +1 Query: 4 MRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKLY 183 MRLLDHPNVV+LKHCFFSTTEKDEL+LNLVLE+VPETVHRVIRHY+KMNQRMPLIYVKLY Sbjct: 119 MRLLDHPNVVTLKHCFFSTTEKDELYLNLVLEFVPETVHRVIRHYSKMNQRMPLIYVKLY 178 Query: 184 SYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYICSR 363 SYQIC +LAYIH VGV HRDIKPQNLLVNPHTHQLK+CDFGSAKVLVKGEPNISYICSR Sbjct: 179 SYQICRSLAYIHNCVGVSHRDIKPQNLLVNPHTHQLKLCDFGSAKVLVKGEPNISYICSR 238 Query: 364 YYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 YYRAPELIFGATEYT+AIDIWSAGCVL EL Sbjct: 239 YYRAPELIFGATEYTSAIDIWSAGCVLGEL 268
>MSK1_MEDSA (P51137) Glycogen synthase kinase-3 homolog MsK-1 (EC 2.7.11.1)| Length = 411 Score = 292 bits (748), Expect = 2e-79 Identities = 135/150 (90%), Positives = 146/150 (97%) Frame = +1 Query: 4 MRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKLY 183 MRLLDHPNVVSLKHCFFSTTEKDEL+LNLVLEYVPETVHRVI+HY+K+NQRMP+IYVKLY Sbjct: 120 MRLLDHPNVVSLKHCFFSTTEKDELYLNLVLEYVPETVHRVIKHYSKLNQRMPMIYVKLY 179 Query: 184 SYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYICSR 363 +YQI AL+YIHR +GVCHRDIKPQNLLVNPHTHQ+K+CDFGSAKVLVKGEPNISYICSR Sbjct: 180 TYQIFRALSYIHRCIGVCHRDIKPQNLLVNPHTHQVKLCDFGSAKVLVKGEPNISYICSR 239 Query: 364 YYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 YYRAPELIFGATEYTTAID+WS GCVLAEL Sbjct: 240 YYRAPELIFGATEYTTAIDVWSVGCVLAEL 269
>MSK1_TOBAC (Q40518) Shaggy-related protein kinase NtK-1 (EC 2.7.11.1)| Length = 409 Score = 291 bits (745), Expect = 5e-79 Identities = 136/150 (90%), Positives = 145/150 (96%) Frame = +1 Query: 4 MRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKLY 183 MRLLDHPNVV LKHCFFSTTEKDE++LNLVLEYVPETVHRVI+HYNK+NQRMPLI VKLY Sbjct: 118 MRLLDHPNVVCLKHCFFSTTEKDEVYLNLVLEYVPETVHRVIKHYNKLNQRMPLILVKLY 177 Query: 184 SYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYICSR 363 +YQI AL+YIH T+GVCHRDIKPQNLLVNPHTHQ+K+CDFGSAKVLVKGEPNISYICSR Sbjct: 178 TYQIFRALSYIHHTIGVCHRDIKPQNLLVNPHTHQVKLCDFGSAKVLVKGEPNISYICSR 237 Query: 364 YYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 YYRAPELIFGATEYTTAIDIWSAGCVLAEL Sbjct: 238 YYRAPELIFGATEYTTAIDIWSAGCVLAEL 267
>KSG5_ARATH (Q8VZD5) Shaggy-related protein kinase epsilon (EC 2.7.11.1)| (ASK-epsilon) Length = 410 Score = 288 bits (738), Expect = 3e-78 Identities = 135/150 (90%), Positives = 144/150 (96%) Frame = +1 Query: 4 MRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKLY 183 MRLLDHPNVVSLKHCFFSTTEKDEL+LNLVLEYVPETV+RV +HY++ NQRMP+IYVKLY Sbjct: 119 MRLLDHPNVVSLKHCFFSTTEKDELYLNLVLEYVPETVYRVSKHYSRANQRMPIIYVKLY 178 Query: 184 SYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYICSR 363 +YQIC ALAYIH VGVCHRDIKPQNLLVNPHTHQ+K+CDFGSAKVLVKGEPNISYICSR Sbjct: 179 TYQICRALAYIHGGVGVCHRDIKPQNLLVNPHTHQVKLCDFGSAKVLVKGEPNISYICSR 238 Query: 364 YYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 YYRAPELIFGATEYTT IDIWSAGCVLAEL Sbjct: 239 YYRAPELIFGATEYTTTIDIWSAGCVLAEL 268
>KSG6_ARATH (Q39010) Shaggy-related protein kinase dzeta (EC 2.7.11.1)| (ASK-dzeta) Length = 412 Score = 272 bits (696), Expect = 3e-73 Identities = 125/151 (82%), Positives = 139/151 (92%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +MRL+DHPNVVSLKHCFFSTT +DELFLNLV+EYVPET++RV++HY NQRMP+ YVKL Sbjct: 116 LMRLMDHPNVVSLKHCFFSTTTRDELFLNLVMEYVPETLYRVLKHYTSSNQRMPIFYVKL 175 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYICS 360 Y+YQI LAYIH GVCHRDIKPQNLLV+PHTHQ K+CDFGSAKVLVKGEPNISYICS Sbjct: 176 YTYQIFRGLAYIHTAPGVCHRDIKPQNLLVDPHTHQCKLCDFGSAKVLVKGEPNISYICS 235 Query: 361 RYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 RYYRAPELIFGATEYT++IDIWSAGCVLAEL Sbjct: 236 RYYRAPELIFGATEYTSSIDIWSAGCVLAEL 266
>KSG8_ARATH (Q96287) Shaggy-related protein kinase theta (EC 2.7.11.1)| (ASK-theta) Length = 472 Score = 267 bits (682), Expect = 1e-71 Identities = 123/151 (81%), Positives = 137/151 (90%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +MRL DHPNVV L+H FFSTT+KDEL+LNLVLEYVPETV+R +HY KMNQ MP+I+V+L Sbjct: 182 IMRLQDHPNVVRLRHSFFSTTDKDELYLNLVLEYVPETVYRASKHYTKMNQHMPIIFVQL 241 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYICS 360 Y+YQIC AL Y+HR VGVCHRDIKPQNLLVNP THQLKICDFGSAK+LV GEPNISYICS Sbjct: 242 YTYQICRALNYLHRVVGVCHRDIKPQNLLVNPQTHQLKICDFGSAKMLVPGEPNISYICS 301 Query: 361 RYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 RYYRAPELIFGATEYT AID+WS GCV+AEL Sbjct: 302 RYYRAPELIFGATEYTNAIDMWSGGCVMAEL 332
>KSG9_ARATH (Q39012) Shaggy-related protein kinase iota (EC 2.7.11.1)| (ASK-iota) Length = 407 Score = 266 bits (681), Expect = 1e-71 Identities = 122/151 (80%), Positives = 137/151 (90%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +MR +DHPNV+SLKHCFFSTT +DELFLNLV+EYVPET++RV+RHY NQRMP+ YVKL Sbjct: 114 LMRPMDHPNVISLKHCFFSTTSRDELFLNLVMEYVPETLYRVLRHYTSSNQRMPIFYVKL 173 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYICS 360 Y+YQI LAYIH GVCHRD+KPQNLLV+P THQ+K+CDFGSAKVLVKGEPNISYICS Sbjct: 174 YTYQIFRGLAYIHTVPGVCHRDVKPQNLLVDPLTHQVKLCDFGSAKVLVKGEPNISYICS 233 Query: 361 RYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 RYYRAPELIFGATEYT +IDIWSAGCVLAEL Sbjct: 234 RYYRAPELIFGATEYTASIDIWSAGCVLAEL 264
>KSGT_BRANA (O04160) Shaggy-related protein kinase theta (EC 2.7.11.1)| (ASK-theta) Length = 468 Score = 265 bits (678), Expect = 3e-71 Identities = 122/151 (80%), Positives = 137/151 (90%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +MRL DHPNVV L+H FFSTT+KDEL+LNLVLE+VPETV+R ++HY KMNQ MP+I V+L Sbjct: 178 IMRLQDHPNVVRLRHSFFSTTDKDELYLNLVLEFVPETVYRALKHYTKMNQHMPIILVQL 237 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYICS 360 Y+YQIC AL Y+HR VGVCHRDIKPQNLLVN HTHQLKICDFGSAK+LV GEPNISYICS Sbjct: 238 YTYQICRALNYLHRVVGVCHRDIKPQNLLVNTHTHQLKICDFGSAKMLVPGEPNISYICS 297 Query: 361 RYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 RYYRAPELIFGATEYT AID+WS GCV+AEL Sbjct: 298 RYYRAPELIFGATEYTNAIDMWSGGCVMAEL 328
>KSG4_ARATH (Q9FVS6) Shaggy-related protein kinase delta (EC 2.7.11.1)| (ASK-delta) Length = 420 Score = 265 bits (676), Expect = 5e-71 Identities = 122/151 (80%), Positives = 137/151 (90%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +M++LDHPNVV LKH F+S TE +E++LNLVLE+VPETV+R R Y++MNQ MPLIYVKL Sbjct: 126 IMQMLDHPNVVCLKHSFYSRTENEEVYLNLVLEFVPETVNRTARSYSRMNQLMPLIYVKL 185 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYICS 360 Y+YQIC LAY+H G+CHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYICS Sbjct: 186 YTYQICRGLAYLHNCCGLCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYICS 245 Query: 361 RYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 RYYRAPELIFGATEYTTAIDIWS GCV+AEL Sbjct: 246 RYYRAPELIFGATEYTTAIDIWSTGCVMAEL 276
>KSG10_ARATH (Q39019) Shaggy-related protein kinase kappa (EC 2.7.11.1)| (ASK-kappa) (AtK-1) Length = 421 Score = 264 bits (675), Expect = 7e-71 Identities = 121/151 (80%), Positives = 139/151 (92%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +M++LDHPN V+LKH FFS T+ +E++LNLVLE+VPETV+RV R Y++ NQ MPLIYVKL Sbjct: 127 IMQMLDHPNAVALKHSFFSRTDNEEVYLNLVLEFVPETVNRVARSYSRTNQLMPLIYVKL 186 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYICS 360 Y+YQIC ALAYIH + G+CHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPN+SYICS Sbjct: 187 YTYQICRALAYIHNSFGLCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNVSYICS 246 Query: 361 RYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 RYYRAPELIFGA+EYTTAIDIWS GCV+AEL Sbjct: 247 RYYRAPELIFGASEYTTAIDIWSTGCVMAEL 277
>KSG7_ARATH (Q39011) Shaggy-related protein kinase eta (EC 2.7.11.1) (ASK-eta)| (BRASSINOSTEROID-INSENSITIVE 2) (ULTRACURVATA1) Length = 380 Score = 263 bits (672), Expect = 2e-70 Identities = 121/151 (80%), Positives = 137/151 (90%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +MR++DHPNVV LKHCFFSTT KDELFLNLV+EYVPE+++RV++HY+ NQRMPL+YVKL Sbjct: 84 LMRVMDHPNVVCLKHCFFSTTSKDELFLNLVMEYVPESLYRVLKHYSSANQRMPLVYVKL 143 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYICS 360 Y YQI LAYIH GVCHRD+KPQNLLV+P THQ+KICDFGSAK LVKGE NISYICS Sbjct: 144 YMYQIFRGLAYIHNVAGVCHRDLKPQNLLVDPLTHQVKICDFGSAKQLVKGEANISYICS 203 Query: 361 RYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 R+YRAPELIFGATEYTT+IDIWSAGCVLAEL Sbjct: 204 RFYRAPELIFGATEYTTSIDIWSAGCVLAEL 234
>KSG2_ARATH (O23145) Shaggy-related protein kinase beta (EC 2.7.11.1)| (ASK-beta) Length = 431 Score = 261 bits (667), Expect = 6e-70 Identities = 119/151 (78%), Positives = 137/151 (90%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +MR+LDHPNVV LKH FFSTTEKDEL+LNLVLEYVPET++R R Y KMNQ MPLIY++L Sbjct: 146 IMRMLDHPNVVELKHSFFSTTEKDELYLNLVLEYVPETIYRASRSYTKMNQHMPLIYIQL 205 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYICS 360 Y+YQIC A+ Y+H+ VGVCHRDIKPQNLLVN TH++KICDFGSAK+L+ GEPNISYICS Sbjct: 206 YTYQICRAMNYLHQVVGVCHRDIKPQNLLVNNVTHEVKICDFGSAKMLIPGEPNISYICS 265 Query: 361 RYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 RYYRAPELIFGATEYT+AID+WS GCV+AEL Sbjct: 266 RYYRAPELIFGATEYTSAIDMWSVGCVMAEL 296
>GSK3B_MOUSE (Q9WV60) Glycogen synthase kinase-3 beta (EC 2.7.11.26) (GSK-3| beta) Length = 420 Score = 225 bits (574), Expect = 4e-59 Identities = 106/152 (69%), Positives = 133/152 (87%), Gaps = 1/152 (0%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEK-DELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVK 177 +MR LDH N+V L++ F+S+ EK DE++LNLVL+YVPETV+RV RHY++ Q +P+IYVK Sbjct: 100 IMRKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVK 159 Query: 178 LYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYIC 357 LY YQ+ +LAYIH + G+CHRDIKPQNLL++P T LK+CDFGSAK LV+GEPN+SYIC Sbjct: 160 LYMYQLFRSLAYIH-SFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYIC 218 Query: 358 SRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 SRYYRAPELIFGAT+YT++ID+WSAGCVLAEL Sbjct: 219 SRYYRAPELIFGATDYTSSIDVWSAGCVLAEL 250
>GSK3B_HUMAN (P49841) Glycogen synthase kinase-3 beta (EC 2.7.11.26) (GSK-3| beta) Length = 420 Score = 225 bits (574), Expect = 4e-59 Identities = 106/152 (69%), Positives = 133/152 (87%), Gaps = 1/152 (0%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEK-DELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVK 177 +MR LDH N+V L++ F+S+ EK DE++LNLVL+YVPETV+RV RHY++ Q +P+IYVK Sbjct: 100 IMRKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVK 159 Query: 178 LYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYIC 357 LY YQ+ +LAYIH + G+CHRDIKPQNLL++P T LK+CDFGSAK LV+GEPN+SYIC Sbjct: 160 LYMYQLFRSLAYIH-SFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYIC 218 Query: 358 SRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 SRYYRAPELIFGAT+YT++ID+WSAGCVLAEL Sbjct: 219 SRYYRAPELIFGATDYTSSIDVWSAGCVLAEL 250
>GSK3B_RAT (P18266) Glycogen synthase kinase-3 beta (EC 2.7.11.26) (GSK-3| beta) (Factor A) (FA) Length = 420 Score = 224 bits (572), Expect = 6e-59 Identities = 106/152 (69%), Positives = 133/152 (87%), Gaps = 1/152 (0%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEK-DELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVK 177 +MR LDH N+V L++ F+S+ EK DE++LNLVL+YVPETV+RV RHY++ Q +P+IYVK Sbjct: 100 IMRKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVK 159 Query: 178 LYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYIC 357 LY YQ+ +LAYIH + G+CHRDIKPQNLL++P T LK+CDFGSAK LV+GEPN+SYIC Sbjct: 160 LYMYQLFRSLAYIH-SFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYIC 218 Query: 358 SRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 SRYYRAPELIFGAT+YT++ID+WSAGCVLAEL Sbjct: 219 SRYYRAPELIFGATDYTSSIDMWSAGCVLAEL 250
>GSK3A_RAT (P18265) Glycogen synthase kinase-3 alpha (EC 2.7.11.26) (GSK-3| alpha) (Factor A) (FA) Length = 483 Score = 223 bits (569), Expect = 1e-58 Identities = 108/152 (71%), Positives = 131/152 (86%), Gaps = 1/152 (0%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEK-DELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVK 177 +MR LDH N+V L++ F+S+ EK DEL+LNLVLEYVPETV+RV RH+ K +P+IYVK Sbjct: 163 IMRKLDHCNIVRLRYFFYSSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLIIPIIYVK 222 Query: 178 LYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYIC 357 +Y YQ+ +LAYIH + GVCHRDIKPQNLLV+P T LK+CDFGSAK LV+GEPN+SYIC Sbjct: 223 VYMYQLFRSLAYIH-SQGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEPNVSYIC 281 Query: 358 SRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 SRYYRAPELIFGAT+YT++ID+WSAGCVLAEL Sbjct: 282 SRYYRAPELIFGATDYTSSIDVWSAGCVLAEL 313
>GSK3A_HUMAN (P49840) Glycogen synthase kinase-3 alpha (EC 2.7.11.26) (GSK-3| alpha) Length = 483 Score = 223 bits (569), Expect = 1e-58 Identities = 107/152 (70%), Positives = 131/152 (86%), Gaps = 1/152 (0%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEK-DELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVK 177 +MR LDH N+V L++ F+S+ EK DEL+LNLVLEYVPETV+RV RH+ K +P++YVK Sbjct: 163 IMRKLDHCNIVRLRYFFYSSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLTIPILYVK 222 Query: 178 LYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYIC 357 +Y YQ+ +LAYIH + GVCHRDIKPQNLLV+P T LK+CDFGSAK LV+GEPN+SYIC Sbjct: 223 VYMYQLFRSLAYIH-SQGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEPNVSYIC 281 Query: 358 SRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 SRYYRAPELIFGAT+YT++ID+WSAGCVLAEL Sbjct: 282 SRYYRAPELIFGATDYTSSIDVWSAGCVLAEL 313
>GSK3H_DICDI (P51136) Glycogen synthase kinase-3 homolog (EC 2.7.11.26) (GSK-3)| Length = 467 Score = 214 bits (544), Expect = 1e-55 Identities = 98/151 (64%), Positives = 129/151 (85%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +M++L+H N+VSLK+ F+ T++ DE++LNLVLEYVP+TV+RV RHY+ Q +P I+VKL Sbjct: 100 IMKMLNHINIVSLKNSFY-TSDNDEVYLNLVLEYVPDTVYRVSRHYSMSKQPVPNIFVKL 158 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYICS 360 Y YQ+C ++ YIH ++G+CHRDIKPQNLL++ T LK+CDFGSAK+L+KGE N+SYICS Sbjct: 159 YIYQLCRSINYIH-SLGICHRDIKPQNLLLDTSTSTLKLCDFGSAKILIKGETNVSYICS 217 Query: 361 RYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 R+YRAPELIFG+T YTT ID+WS GCVLAEL Sbjct: 218 RHYRAPELIFGSTNYTTTIDVWSLGCVLAEL 248
>SGG_DROME (P18431) Protein kinase shaggy (EC 2.7.11.1) (Protein zeste-white 3)| Length = 1067 Score = 211 bits (537), Expect = 7e-55 Identities = 100/152 (65%), Positives = 126/152 (82%), Gaps = 1/152 (0%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEK-DELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVK 177 +MR L+H N+V L + F+S+ EK DE+FLNLVLEY+PETV++V R Y K Q +P+ +++ Sbjct: 651 IMRKLEHCNIVKLLYFFYSSGEKRDEVFLNLVLEYIPETVYKVARQYAKTKQTIPINFIR 710 Query: 178 LYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYIC 357 LY YQ+ +LAYIH ++G+CHRDIKPQNLL++P T LK+CDFGSAK L+ GEPN+SYIC Sbjct: 711 LYMYQLFRSLAYIH-SLGICHRDIKPQNLLLDPETAVLKLCDFGSAKQLLHGEPNVSYIC 769 Query: 358 SRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 SRYYRAPELIFGA YTT ID+WSAGCVLAEL Sbjct: 770 SRYYRAPELIFGAINYTTKIDVWSAGCVLAEL 801
>GSK3_SCHPO (Q10452) Protein kinase gsk3 (EC 2.7.11.1) (Protein kinaae skp1)| Length = 387 Score = 204 bits (518), Expect = 1e-52 Identities = 95/152 (62%), Positives = 123/152 (80%), Gaps = 1/152 (0%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEK-DELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVK 177 +MR++ HPN+V L +++T + DE++LNLVLE++PET++R R Y + MP++ VK Sbjct: 76 IMRIMKHPNIVDLIAYYYTTGDNSDEVYLNLVLEFMPETIYRASRLYTRQKLSMPMLEVK 135 Query: 178 LYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYIC 357 LY YQ+ +LAYIH + G+CHRDIKPQNLL++P LK+CDFGSAK+LV GEPN+SYIC Sbjct: 136 LYIYQLLRSLAYIHAS-GICHRDIKPQNLLLDPENGILKLCDFGSAKILVAGEPNVSYIC 194 Query: 358 SRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 SRYYRAPELIFGAT+YT AIDIWS GCV+AEL Sbjct: 195 SRYYRAPELIFGATDYTHAIDIWSTGCVMAEL 226
>GSK3H_DROME (P83101) Putative glycogen synthase kinase-3 homolog (EC 2.7.11.26)| (GSK-3) (Protein gasket) Length = 501 Score = 198 bits (503), Expect = 6e-51 Identities = 90/152 (59%), Positives = 125/152 (82%), Gaps = 1/152 (0%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEK-DELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVK 177 +MR L H N+++LK FFS+ EK DE++LNLV+E++PET+++V R Y + Q +P+ +V+ Sbjct: 77 IMRKLRHDNIITLKWFFFSSGEKRDEVYLNLVMEFLPETLYKVERQYARAKQTLPVNFVR 136 Query: 178 LYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYIC 357 LY YQ+ ++ Y+H ++G CHRDIKPQN+L++ T LK+CDFGSAK L+ GEPN+SYIC Sbjct: 137 LYMYQLLRSMGYLH-SLGFCHRDIKPQNMLLDSETGVLKLCDFGSAKQLISGEPNVSYIC 195 Query: 358 SRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 SRYYRAPELIFG+T+YTT ID+WSAGCV++EL Sbjct: 196 SRYYRAPELIFGSTDYTTKIDMWSAGCVMSEL 227
>MRK1_YEAST (P50873) Serine/threonine-protein kinase MRK1 (EC 2.7.11.1)| Length = 501 Score = 192 bits (489), Expect = 3e-49 Identities = 82/150 (54%), Positives = 116/150 (77%) Frame = +1 Query: 4 MRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKLY 183 M++L HPN V L++ F+ E+DE++LNLVL+Y+P+++++ +RH+ + +MP + +K Y Sbjct: 209 MKMLCHPNTVGLQYYFYEKDEEDEVYLNLVLDYMPQSLYQRLRHFVNLKMQMPRVEIKFY 268 Query: 184 SYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYICSR 363 +YQ+ AL Y+H +CHRDIKPQNLLV+P T KICDFGSAK L +PN+SYICSR Sbjct: 269 AYQLFKALNYLHNVPRICHRDIKPQNLLVDPTTFSFKICDFGSAKCLKPDQPNVSYICSR 328 Query: 364 YYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 YYRAPEL+FGAT Y+ +D+WS+ CV+AEL Sbjct: 329 YYRAPELMFGATNYSNQVDVWSSACVIAEL 358
>MDS1_YEAST (P38615) Serine/threonine-protein kinase MDS1/RIM11 (EC 2.7.11.1)| Length = 370 Score = 190 bits (483), Expect = 1e-48 Identities = 84/151 (55%), Positives = 114/151 (75%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +M++L H N++ LK+ F+ +DE++LNL+LEY+P+++++ +RH+ M + +K Sbjct: 83 IMKMLSHINIIDLKYFFYERDSQDEIYLNLILEYMPQSLYQRLRHFVHQRTPMSRLEIKY 142 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYICS 360 Y +Q+ +L Y+H VCHRDIKPQNLLV+P T LK+CDFGSAK L EPN+SYICS Sbjct: 143 YMFQLFKSLNYLHHFANVCHRDIKPQNLLVDPETWSLKLCDFGSAKQLKPTEPNVSYICS 202 Query: 361 RYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 RYYRAPELIFGAT YT IDIWS+GCV+AEL Sbjct: 203 RYYRAPELIFGATNYTNQIDIWSSGCVMAEL 233
>GSK31_SCHPO (Q9URT9) Protein kinase gsk31 (EC 2.7.11.1)| Length = 381 Score = 187 bits (476), Expect = 8e-48 Identities = 94/153 (61%), Positives = 116/153 (75%), Gaps = 2/153 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFST--TEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYV 174 +MR + HPN++ L FF T KDE L L+LEY+PETV +R Y + + +P + + Sbjct: 69 IMRAISHPNIIKLI-AFFHTHNPSKDETHLCLLLEYMPETVFDDMRWYTRRRKSIPNLSI 127 Query: 175 KLYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYI 354 KLY++Q+ ALAY+H T GVCHRDIKPQNLLV+ T LK+CDFGSAKVLV EPN+SYI Sbjct: 128 KLYAFQLFRALAYLHST-GVCHRDIKPQNLLVDYKTGILKLCDFGSAKVLVPSEPNVSYI 186 Query: 355 CSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 CSRYYRAPEL+FGAT YTT ID+WSA CV+AEL Sbjct: 187 CSRYYRAPELVFGATHYTTKIDVWSAACVIAEL 219
>MCK1_YEAST (P21965) Protein kinase MCK1 (EC 2.7.11.1) (Meiosis and centromere| regulatory kinase) Length = 375 Score = 167 bits (424), Expect = 9e-42 Identities = 79/152 (51%), Positives = 109/152 (71%), Gaps = 1/152 (0%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKD-ELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVK 177 ++R+ DHPN+V L++ F + +D +++ +L +E +PET+ I Y MPL +++ Sbjct: 83 ILRIADHPNIVKLQYFFTHLSPQDNKVYQHLAMECLPETLQIEINRYVTNKLEMPLKHIR 142 Query: 178 LYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYIC 357 LY+YQI + Y+H +GVCHRDIKP N+LV+P T LKICDFGSAK L +P+ISYIC Sbjct: 143 LYTYQIARGMLYLHG-LGVCHRDIKPSNVLVDPETGVLKICDFGSAKKLEHNQPSISYIC 201 Query: 358 SRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 SR+YRAPELI G T+YTT IDIW GCV+ E+ Sbjct: 202 SRFYRAPELIIGCTQYTTQIDIWGLGCVMGEM 233
>KOM8_YEAST (Q12222) Probable serine/threonine-protein kinase YOL128C (EC| 2.7.11.1) Length = 375 Score = 132 bits (332), Expect = 4e-31 Identities = 66/155 (42%), Positives = 100/155 (64%), Gaps = 4/155 (2%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFS-TTEKDELFL---NLVLEYVPETVHRVIRHYNKMNQRMPLI 168 +++ + HPN+V+L+ F S T KD L N V+EY+P+T+ I Y +MP Sbjct: 89 ILQNIRHPNLVTLEFFFESHCTTKDGGHLYQKNFVMEYIPQTLSSEIHEYFDNGSKMPTK 148 Query: 169 YVKLYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNIS 348 ++KLY++QI AL +H ++ +CH D+KP N+L+ P + K+CDFGSA+ L + Sbjct: 149 HIKLYTFQILRALLTLH-SMSICHGDLKPSNILIIPSSGIAKVCDFGSAQRLDDNTELKT 207 Query: 349 YICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 Y CSR+YRAPEL+ + +YTT IDIWS GC++ E+ Sbjct: 208 YFCSRFYRAPELLLNSKDYTTQIDIWSLGCIIGEM 242
>MPK5_ARATH (Q39025) Mitogen-activated protein kinase homolog 5 (EC 2.7.11.24)| (MAP kinase 5) (AtMPK5) Length = 376 Score = 113 bits (282), Expect = 3e-25 Identities = 59/151 (39%), Positives = 92/151 (60%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 ++R L+H NVV +K ++D + + +V E + +H++IR +N + + Sbjct: 93 LLRHLEHENVVVIKDIIRPPKKEDFVDVYIVFELMDTDLHQIIRSNQSLNDD----HCQY 148 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYICS 360 + YQI L YIH + V HRD+KP NLL+N + LKI DFG A+ + E Y+ + Sbjct: 149 FLYQILRGLKYIH-SANVLHRDLKPSNLLLNSNC-DLKITDFGLARTTSETEYMTEYVVT 206 Query: 361 RYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 R+YRAPEL+ ++EYT+AID+WS GC+ AE+ Sbjct: 207 RWYRAPELLLNSSEYTSAIDVWSVGCIFAEI 237
>NTF6_TOBAC (Q40531) Mitogen-activated protein kinase homolog NTF6 (EC| 2.7.11.24) (P43) Length = 371 Score = 108 bits (271), Expect = 5e-24 Identities = 56/147 (38%), Positives = 87/147 (59%) Frame = +1 Query: 13 LDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKLYSYQ 192 +DH N++ +K ++ + +V E + +H++IR +Q + + + + YQ Sbjct: 92 MDHENIIKIKDIVRPPDREEFNDVYIVYELMDTDLHQIIRS----SQALTDDHCQYFLYQ 147 Query: 193 ICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYICSRYYR 372 + L Y+H + V HRD+KP NLL+N + LKICDFG A+ + + Y+ +R+YR Sbjct: 148 LLRGLKYVH-SANVLHRDLKPSNLLLNANC-DLKICDFGLARTTSEADFMTEYVVTRWYR 205 Query: 373 APELIFGATEYTTAIDIWSAGCVLAEL 453 APEL+ TEYT AIDIWS GC+L EL Sbjct: 206 APELLLNCTEYTAAIDIWSVGCILMEL 232
>MMK1_MEDSA (Q07176) Mitogen-activated protein kinase homolog MMK1 (EC| 2.7.11.24) (MAP kinase MSK7) (MAP kinase ERK1) Length = 387 Score = 108 bits (269), Expect = 8e-24 Identities = 59/153 (38%), Positives = 94/153 (61%), Gaps = 2/153 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEY--VPETVHRVIRHYNKMNQRMPLIYV 174 ++R +DH NVV+++ + E+F ++ + Y + +H++IR NQ + + Sbjct: 105 LLRHMDHENVVAIRDIV--PPPQREVFNDVYIAYELMDTDLHQIIRS----NQALSEEHC 158 Query: 175 KLYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYI 354 + + YQI L YIH + V HRD+KP NLL+N + LKICDFG A+V + + Y+ Sbjct: 159 QYFLYQILRGLKYIH-SANVLHRDLKPSNLLLNANC-DLKICDFGLARVTSETDFMTEYV 216 Query: 355 CSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 +R+YRAPEL+ +++YT AID+WS GC+ EL Sbjct: 217 VTRWYRAPELLLNSSDYTAAIDVWSVGCIFMEL 249
>MPK6_ARATH (Q39026) Mitogen-activated protein kinase homolog 6 (EC 2.7.11.24)| (MAP kinase 6) (AtMPK6) Length = 395 Score = 108 bits (269), Expect = 8e-24 Identities = 56/151 (37%), Positives = 89/151 (58%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 ++R +DH N+V+++ + + E + +H++IR NQ + + + Sbjct: 113 LLRHMDHENIVAIRDIIPPPLRNAFNDVYIAYELMDTDLHQIIRS----NQALSEEHCQY 168 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYICS 360 + YQI L YIH + V HRD+KP NLL+N + LKICDFG A+V + + Y+ + Sbjct: 169 FLYQILRGLKYIH-SANVLHRDLKPSNLLLNANC-DLKICDFGLARVTSESDFMTEYVVT 226 Query: 361 RYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 R+YRAPEL+ +++YT AID+WS GC+ EL Sbjct: 227 RWYRAPELLLNSSDYTAAIDVWSVGCIFMEL 257
>MMK2_MEDSA (Q40353) Mitogen-activated protein kinase homolog MMK2 (EC| 2.7.11.24) Length = 371 Score = 107 bits (268), Expect = 1e-23 Identities = 57/151 (37%), Positives = 91/151 (60%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 ++R +DH NV+S+K +++ + +V E + +H++IR NQ M + + Sbjct: 87 LLRHMDHENVMSIKDIIRPPQKENFNHVYIVSELMDTDLHQIIRS----NQPMTDDHCRY 142 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYICS 360 + YQ+ L Y+H + V HRD+KP NLL+N + LKI DFG A+ + + Y+ + Sbjct: 143 FVYQLLRGLKYVH-SANVLHRDLKPSNLLLNANC-DLKIGDFGLARTTSETDFMTEYVVT 200 Query: 361 RYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 R+YRAPEL+ ++YT AIDIWS GC+L E+ Sbjct: 201 RWYRAPELLLNCSDYTAAIDIWSVGCILGEI 231
>MAPK_PEA (Q06060) Mitogen-activated protein kinase homolog D5 (EC 2.7.11.24)| Length = 394 Score = 107 bits (268), Expect = 1e-23 Identities = 59/153 (38%), Positives = 94/153 (61%), Gaps = 2/153 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEY--VPETVHRVIRHYNKMNQRMPLIYV 174 ++R +DH NVV+++ + E+F ++ + Y + +H++IR NQ + + Sbjct: 112 LVRHMDHENVVAIRDIV--PPPQREVFNDVYIAYELMDTDLHQIIRS----NQALSEEHC 165 Query: 175 KLYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYI 354 + + YQI L YIH + V HRD+KP NLL+N + LKICDFG A+V + + Y+ Sbjct: 166 QYFLYQILRGLKYIH-SANVLHRDLKPSNLLLNANC-DLKICDFGLARVTSETDFMTEYV 223 Query: 355 CSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 +R+YRAPEL+ +++YT AID+WS GC+ EL Sbjct: 224 VTRWYRAPELLLNSSDYTAAIDVWSVGCIFMEL 256
>NTF4_TOBAC (Q40532) Mitogen-activated protein kinase homolog NTF4 (EC| 2.7.11.24) (P45) Length = 393 Score = 107 bits (267), Expect = 1e-23 Identities = 56/151 (37%), Positives = 90/151 (59%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 ++R +DH N+V+++ + + + E + +H++IR NQ + + + Sbjct: 110 LLRHMDHENIVAIRDIIPPPQREAFNDVYIAYELMDTDLHQIIRS----NQGLSEEHCQY 165 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYICS 360 + YQI L YIH + V HRD+KP NLL+N + LKICDFG A+V + + Y+ + Sbjct: 166 FLYQILRGLKYIH-SANVLHRDLKPSNLLLNANC-DLKICDFGLARVTSETDFMTEYVVT 223 Query: 361 RYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 R+YRAPEL+ +++YT AID+WS GC+ EL Sbjct: 224 RWYRAPELLLNSSDYTAAIDVWSVGCIFMEL 254
>MPK3_ARATH (Q39023) Mitogen-activated protein kinase homolog 3 (EC 2.7.11.24)| (MAP kinase 3) (AtMPK3) Length = 370 Score = 105 bits (263), Expect = 4e-23 Identities = 53/151 (35%), Positives = 89/151 (58%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 ++R LDH N+++++ + + + E + +H++IR NQ + + + Sbjct: 88 LLRHLDHENIIAIRDVVPPPLRRQFSDVYISTELMDTDLHQIIRS----NQSLSEEHCQY 143 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYICS 360 + YQ+ L YIH + + HRD+KP NLL+N + LKICDFG A+ + + Y+ + Sbjct: 144 FLYQLLRGLKYIH-SANIIHRDLKPSNLLLNANC-DLKICDFGLARPTSENDFMTEYVVT 201 Query: 361 RYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 R+YRAPEL+ +++YT AID+WS GC+ EL Sbjct: 202 RWYRAPELLLNSSDYTAAIDVWSVGCIFMEL 232
>MPK2_ARATH (Q39022) Mitogen-activated protein kinase homolog 2 (EC 2.7.11.24)| (MAP kinase 2) (AtMPK2) Length = 376 Score = 105 bits (261), Expect = 7e-23 Identities = 59/152 (38%), Positives = 90/152 (59%), Gaps = 1/152 (0%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 ++R L H NVV+LK + ++ + LV E + +H++I K +Q + + + Sbjct: 82 LLRHLRHENVVALKDVMMANHKRSFKDVYLVYELMDTDLHQII----KSSQVLSNDHCQY 137 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVL-VKGEPNISYIC 357 + +Q+ L YIH + + HRD+KP NLLVN + LKICDFG A+ KG+ Y+ Sbjct: 138 FLFQLLRGLKYIH-SANILHRDLKPGNLLVNANC-DLKICDFGLARTSNTKGQFMTEYVV 195 Query: 358 SRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 +R+YRAPEL+ Y T+ID+WS GC+ AEL Sbjct: 196 TRWYRAPELLLCCDNYGTSIDVWSVGCIFAEL 227
>ICK_MOUSE (Q9JKV2) Serine/threonine-protein kinase ICK (EC 2.7.11.22)| (Intestinal cell kinase) (mICK) (MAK-related kinase) (MRK) Length = 629 Score = 103 bits (258), Expect = 2e-22 Identities = 57/151 (37%), Positives = 92/151 (60%), Gaps = 1/151 (0%) Frame = +1 Query: 4 MRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKLY 183 ++ L+H N+V LK E D L+ + EY+ E ++++I+ NK+ P ++ Sbjct: 54 LKKLNHANIVKLKEVI---RENDHLYF--IFEYMKENLYQLIKERNKL---FPESAIRNI 105 Query: 184 SYQICXALAYIHRTVGVCHRDIKPQNLL-VNPHTHQLKICDFGSAKVLVKGEPNISYICS 360 YQI LA+IH+ G HRD+KP+NLL + P +KI DFG A+ + P Y+ + Sbjct: 106 MYQILQGLAFIHKH-GFFHRDLKPENLLCMGPEL--VKIADFGLAREIRSRPPYTDYVST 162 Query: 361 RYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 R+YRAPE++ +T Y++ IDIW+ GC++AE+ Sbjct: 163 RWYRAPEVLLRSTNYSSPIDIWAVGCIMAEV 193
>ICK_HUMAN (Q9UPZ9) Serine/threonine-protein kinase ICK (EC 2.7.11.22)| (Intestinal cell kinase) (hICK) (MAK-related kinase) (MRK) (Laryngeal cancer kinase 2) (LCK2) Length = 632 Score = 103 bits (258), Expect = 2e-22 Identities = 57/151 (37%), Positives = 92/151 (60%), Gaps = 1/151 (0%) Frame = +1 Query: 4 MRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKLY 183 ++ L+H NVV LK E D L+ + EY+ E ++++I+ NK+ P ++ Sbjct: 54 LKKLNHANVVKLKEVI---RENDHLYF--IFEYMKENLYQLIKERNKL---FPESAIRNI 105 Query: 184 SYQICXALAYIHRTVGVCHRDIKPQNLL-VNPHTHQLKICDFGSAKVLVKGEPNISYICS 360 YQI LA+IH+ G HRD+KP+NLL + P +KI DFG A+ + P Y+ + Sbjct: 106 MYQILQGLAFIHKH-GFFHRDLKPENLLCMGPEL--VKIADFGLAREIRSKPPYTDYVST 162 Query: 361 RYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 R+YRAPE++ +T Y++ ID+W+ GC++AE+ Sbjct: 163 RWYRAPEVLLRSTNYSSPIDVWAVGCIMAEV 193
>MPK4_ARATH (Q39024) Mitogen-activated protein kinase homolog 4 (EC 2.7.11.24)| (MAP kinase 4) (AtMPK4) Length = 376 Score = 103 bits (257), Expect = 2e-22 Identities = 54/150 (36%), Positives = 89/150 (59%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +++ +DH NV+++K ++ + +V E + +H++IR NQ + + + Sbjct: 93 LLKHMDHENVIAVKDIIKPPQRENFNDVYIVYELMDTDLHQIIRS----NQPLTDDHCRF 148 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYICS 360 + YQ+ L Y+H + V HRD+KP NLL+N + LK+ DFG A+ + + Y+ + Sbjct: 149 FLYQLLRGLKYVH-SANVLHRDLKPSNLLLNANC-DLKLGDFGLARTKSETDFMTEYVVT 206 Query: 361 RYYRAPELIFGATEYTTAIDIWSAGCVLAE 450 R+YRAPEL+ +EYT AIDIWS GC+L E Sbjct: 207 RWYRAPELLLNCSEYTAAIDIWSVGCILGE 236
>ICK_RAT (Q62726) Serine/threonine-protein kinase ICK (EC 2.7.11.22)| (Intestinal cell kinase) (MAK-related kinase) (MRK) Length = 629 Score = 103 bits (257), Expect = 2e-22 Identities = 56/151 (37%), Positives = 92/151 (60%), Gaps = 1/151 (0%) Frame = +1 Query: 4 MRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKLY 183 ++ L+H N+V LK E D L+ + EY+ E ++++I+ NK+ P ++ Sbjct: 54 LKKLNHANIVKLKEVI---RENDHLYF--IFEYMKENLYQLIKERNKL---FPESAIRNI 105 Query: 184 SYQICXALAYIHRTVGVCHRDIKPQNLL-VNPHTHQLKICDFGSAKVLVKGEPNISYICS 360 YQI LA+IH+ G HRD+KP+NLL + P +KI DFG A+ + P Y+ + Sbjct: 106 MYQILQGLAFIHKH-GFFHRDLKPENLLCMGPEL--VKIADFGLAREIRSRPPYTDYVST 162 Query: 361 RYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 R+YRAPE++ +T Y++ ID+W+ GC++AE+ Sbjct: 163 RWYRAPEVLLRSTNYSSPIDVWAVGCIMAEV 193
>CDKL1_RAT (Q66HE7) Cyclin-dependent kinase-like 1 (EC 2.7.11.22)| Length = 352 Score = 102 bits (254), Expect = 4e-22 Identities = 56/152 (36%), Positives = 91/152 (59%), Gaps = 1/152 (0%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 M++ L HPN+VSL F + + L+LV EY H V+ ++ + +P VK Sbjct: 54 MLKQLKHPNLVSLLEVF-----RRKRRLHLVFEYCH---HTVLHELDRYQRGVPEPLVKN 105 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLV-KGEPNISYIC 357 ++Q A+ + H+ HRD+KP+N+L+ H+ +K+CDFG A++L G+ Y+ Sbjct: 106 ITWQTLQAVNFCHKH-NCIHRDVKPENILITKHS-VIKLCDFGFARLLTGPGDYYTDYVA 163 Query: 358 SRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 +R+YR+PEL+ G T+Y +D+W+ GCV AEL Sbjct: 164 TRWYRSPELLVGDTQYGPPVDVWAIGCVFAEL 195
>MPK1_ARATH (Q39021) Mitogen-activated protein kinase homolog 1 (EC 2.7.11.24)| (MAP kinase 1) (AtMPK1) Length = 370 Score = 102 bits (254), Expect = 4e-22 Identities = 58/152 (38%), Positives = 88/152 (57%), Gaps = 1/152 (0%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 ++R L H NV++LK + + LV E + +H++I K +Q + + + Sbjct: 82 LLRHLRHENVIALKDVMMPIHKMSFKDVYLVYELMDTDLHQII----KSSQVLSNDHCQY 137 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVL-VKGEPNISYIC 357 + +Q+ L YIH + + HRD+KP NLLVN + LKICDFG A+ KG+ Y+ Sbjct: 138 FLFQLLRGLKYIH-SANILHRDLKPGNLLVNANC-DLKICDFGLARASNTKGQFMTEYVV 195 Query: 358 SRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 +R+YRAPEL+ Y T+ID+WS GC+ AEL Sbjct: 196 TRWYRAPELLLCCDNYGTSIDVWSVGCIFAEL 227
>ERK1_CANAL (P28869) Extracellular signal-regulated kinase 1 (EC 2.7.11.24)| (ERK1) (MAP kinase 1) (MAPK 1) Length = 417 Score = 102 bits (254), Expect = 4e-22 Identities = 57/155 (36%), Positives = 89/155 (57%), Gaps = 4/155 (2%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +++ +H N++S+ + + L+ E + +HRVIR N + +++ Sbjct: 117 LLKHFNHENIISILAIQRPINYESFNEIYLIQELMETDLHRVIRTQNLSDD-----HIQY 171 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNIS---- 348 + YQ AL +H + V HRD+KP NLL+N + LKICDFG A+ + E N Sbjct: 172 FIYQTLRALKAMH-SANVLHRDLKPSNLLLNSNC-DLKICDFGLARSIASQEDNYGFMTE 229 Query: 349 YICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 Y+ +R+YRAPE++ EYTTAID+WS GC+LAE+ Sbjct: 230 YVATRWYRAPEIMLTFQEYTTAIDVWSVGCILAEM 264
>CDKL4_MOUSE (Q3TZA2) Cyclin-dependent kinase-like 4 (EC 2.7.11.22)| Length = 342 Score = 102 bits (254), Expect = 4e-22 Identities = 55/152 (36%), Positives = 93/152 (61%), Gaps = 1/152 (0%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETV-HRVIRHYNKMNQRMPLIYVK 177 M++ L HPN+V+L F + + ++LV EY T+ + + R+ N ++ + +K Sbjct: 54 MLKQLKHPNLVNLIEVF-----RRKRKMHLVFEYCDHTLLNELERNPNGVSDGV----IK 104 Query: 178 LYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYIC 357 +Q AL + H+ HRD+KP+N+L+ +KICDFG A++L+ G+ Y+ Sbjct: 105 SVLWQTLQALNFCHKH-NCIHRDVKPENILITKQG-MIKICDFGFARILIPGDAYTDYVA 162 Query: 358 SRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 +R+YRAPEL+ G T+Y +++D+W+ GCV AEL Sbjct: 163 TRWYRAPELLVGDTKYGSSVDVWAVGCVFAEL 194
>HOG1_CANAL (Q92207) Mitogen-activated protein kinase HOG1 (EC 2.7.11.24) (MAP| kinase HOG1) Length = 377 Score = 101 bits (252), Expect = 8e-22 Identities = 58/152 (38%), Positives = 92/152 (60%), Gaps = 1/152 (0%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +++ L H N+++L F S E D F+N E +HR++ Q +++ Sbjct: 73 LLKHLKHENLITLDDIFISPLE-DIYFVN---ELQGTDLHRLLNSRPLEKQ-----FIQY 123 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNIS-YIC 357 ++YQI L YIH + GV HRD+KP N+L+N + LKICDFG A++ +P ++ Y+ Sbjct: 124 FTYQIMRGLKYIH-SAGVIHRDLKPSNILINENC-DLKICDFGLARLQ---DPQMTGYVS 178 Query: 358 SRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 +RYYRAPE++ +Y T +D+WS GC+LAE+ Sbjct: 179 TRYYRAPEIMLTWQKYDTEVDLWSVGCILAEM 210
>STY1_SCHPO (Q09892) Mitogen-activated protein kinase sty1 (EC 2.7.11.24) (MAP| kinase sty1) (MAP kinase spc1) Length = 349 Score = 100 bits (249), Expect = 2e-21 Identities = 54/152 (35%), Positives = 91/152 (59%), Gaps = 1/152 (0%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +++ L H N++SL F S E + V E + +HR++ ++ + +++ Sbjct: 70 LLKHLRHENIISLSDIFISPFED----IYFVTELLGTDLHRLLT-----SRPLETQFIQY 120 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNIS-YIC 357 + YQI L ++H + GV HRD+KP N+L+N + LKICDFG A++ +P ++ Y+ Sbjct: 121 FLYQILRGLKFVH-SAGVIHRDLKPSNILINENC-DLKICDFGLARIQ---DPQMTGYVS 175 Query: 358 SRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 +RYYRAPE++ +Y +DIWSAGC+ AE+ Sbjct: 176 TRYYRAPEIMLTWQKYNVEVDIWSAGCIFAEM 207
>MOK_MOUSE (Q9WVS4) MAPK/MAK/MRK overlapping kinase (EC 2.7.11.22) (MOK| protein kinase) Length = 420 Score = 100 bits (248), Expect = 2e-21 Identities = 58/153 (37%), Positives = 88/153 (57%), Gaps = 2/153 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVK- 177 + RL HPN+++L F ++ L L+ E + ++ +IR +R PL K Sbjct: 54 LRRLNPHPNILALHEVVF---DRKSGSLALICELMDMNIYELIR-----GRRHPLSEKKI 105 Query: 178 -LYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYI 354 LY YQ+C +L ++HR G+ HRD+KP+N+LV LK+ DFGS + + +P YI Sbjct: 106 MLYMYQLCKSLDHMHRN-GIFHRDVKPENILVKQDV--LKLGDFGSCRSVYSKQPYTEYI 162 Query: 355 CSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 +R+YRAPE + YT +D+WSAGCV E+ Sbjct: 163 STRWYRAPECLLTDGFYTYKMDLWSAGCVFYEI 195
>CDKL5_HUMAN (O76039) Cyclin-dependent kinase-like 5 (EC 2.7.11.22)| (Serine/threonine-protein kinase 9) Length = 1030 Score = 100 bits (248), Expect = 2e-21 Identities = 60/153 (39%), Positives = 91/153 (59%), Gaps = 2/153 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 M+R L N+V LK F + +L+L V EYV + + ++ +M +P VK Sbjct: 63 MLRTLKQENIVELKEAF---RRRGKLYL--VFEYVEKNMLELLE---EMPNGVPPEKVKS 114 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPN--ISYI 354 Y YQ+ A+ + H+ + HRDIKP+NLL++ H LK+CDFG A+ L +G Y+ Sbjct: 115 YIYQLIKAIHWCHKN-DIVHRDIKPENLLIS-HNDVLKLCDFGFARNLSEGNNANYTEYV 172 Query: 355 CSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 +R+YR+PEL+ GA Y ++D+WS GC+L EL Sbjct: 173 ATRWYRSPELLLGAP-YGKSVDMWSVGCILGEL 204
>MPK7_ARATH (Q39027) Mitogen-activated protein kinase homolog 7 (EC 2.7.11.24)| (MAP kinase 7) (AtMPK7) Length = 368 Score = 100 bits (248), Expect = 2e-21 Identities = 55/152 (36%), Positives = 87/152 (57%), Gaps = 1/152 (0%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 ++R + H NV++LK + LV E + +H++I K +Q + + K Sbjct: 82 LLRHVRHENVIALKDVMLPANRSSFKDVYLVYELMDTDLHQII----KSSQSLSDDHCKY 137 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNIS-YIC 357 + +Q+ L Y+H + + HRD+KP NLLVN + LKICDFG A+ E ++ Y+ Sbjct: 138 FLFQLLRGLKYLH-SANILHRDLKPGNLLVNANC-DLKICDFGLARTSQGNEQFMTEYVV 195 Query: 358 SRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 +R+YRAPEL+ Y T+ID+WS GC+ AE+ Sbjct: 196 TRWYRAPELLLCCDNYGTSIDVWSVGCIFAEI 227
>MOK_HUMAN (Q9UQ07) MAPK/MAK/MRK overlapping kinase (EC 2.7.11.22) (MOK| protein kinase) (Renal tumor antigen 1) (RAGE-1) Length = 419 Score = 99.8 bits (247), Expect = 3e-21 Identities = 57/153 (37%), Positives = 87/153 (56%), Gaps = 2/153 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 + RL HPN++ L F ++ L L+ E + ++ +IR +R PL K+ Sbjct: 54 LRRLNPHPNILMLHEVVF---DRKSGSLALICELMDMNIYELIR-----GRRYPLSEKKI 105 Query: 181 --YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYI 354 Y YQ+C +L +IHR G+ HRD+KP+N+L+ LK+ DFGS + + +P YI Sbjct: 106 MHYMYQLCKSLDHIHRN-GIFHRDVKPENILIKQDV--LKLGDFGSCRSVYSKQPYTEYI 162 Query: 355 CSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 +R+YRAPE + YT +D+WSAGCV E+ Sbjct: 163 STRWYRAPECLLTDGFYTYKMDLWSAGCVFYEI 195
>CDKL1_HUMAN (Q00532) Cyclin-dependent kinase-like 1 (EC 2.7.11.22)| (Serine/threonine-protein kinase KKIALRE) (Protein kinase p42 KKIALRE) Length = 357 Score = 99.8 bits (247), Expect = 3e-21 Identities = 54/152 (35%), Positives = 90/152 (59%), Gaps = 1/152 (0%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 M++ L HPN+V+L F + + L+LV EY H V+ ++ + +P VK Sbjct: 54 MLKQLKHPNLVNLLEVF-----RRKRRLHLVFEYCD---HTVLHELDRYQRGVPEHLVKS 105 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLV-KGEPNISYIC 357 ++Q A+ + H+ HRD+KP+N+L+ H+ +K+CDFG A++L + Y+ Sbjct: 106 ITWQTLQAVNFCHKH-NCIHRDVKPENILITKHS-VIKLCDFGFARLLTGPSDYYTDYVA 163 Query: 358 SRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 +R+YR+PEL+ G T+Y +D+W+ GCV AEL Sbjct: 164 TRWYRSPELLVGDTQYGPPVDVWAIGCVFAEL 195
>HOG1_DEBHA (Q9UV50) Mitogen-activated protein kinase HOG1 (EC 2.7.11.24) (MAP| kinase HOG1) Length = 387 Score = 99.4 bits (246), Expect = 4e-21 Identities = 54/152 (35%), Positives = 90/152 (59%), Gaps = 1/152 (0%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +++ L H N+++L F S E + V E +HR++ Q +++ Sbjct: 73 LLKHLRHENLITLDDIFLSPLED----IYFVTELQGTDLHRLLTSRPLEKQ-----FIQY 123 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNIS-YIC 357 ++YQI L Y+H + GV HRD+KP N+L+N + LKICDFG A++ +P ++ Y+ Sbjct: 124 FTYQILRGLKYVH-SAGVIHRDLKPSNILINENC-DLKICDFGLARIQ---DPQMTGYVS 178 Query: 358 SRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 +RYYRAPE++ +Y T +D+WS GC+L+E+ Sbjct: 179 TRYYRAPEIMLTWQKYDTEVDLWSVGCILSEM 210
>NTF3_TOBAC (Q40517) Mitogen-activated protein kinase homolog NTF3 (EC| 2.7.11.24) (P43) Length = 372 Score = 99.4 bits (246), Expect = 4e-21 Identities = 55/152 (36%), Positives = 87/152 (57%), Gaps = 1/152 (0%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 ++R L H NV++LK + + LV E + +H++I K +Q + + + Sbjct: 82 LLRHLRHENVIALKDVMMPIHRRSFKDVYLVYELMDTDLHQII----KSSQTLSNDHCQY 137 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLV-KGEPNISYIC 357 + +Q+ L Y+H + + HRD+KP NLL+N + LKICDFG A+ K + Y+ Sbjct: 138 FLFQLLRGLKYLH-SANILHRDLKPGNLLINANC-DLKICDFGLARTSSGKDQFMTEYVV 195 Query: 358 SRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 +R+YRAPEL+ Y T+ID+WS GC+ AEL Sbjct: 196 TRWYRAPELLLCCDNYGTSIDVWSVGCIFAEL 227
>HOG1_CANGA (Q6FIU2) Mitogen-activated protein kinase HOG1 (EC 2.7.11.24) (MAP| kinase HOG1) Length = 447 Score = 99.4 bits (246), Expect = 4e-21 Identities = 56/152 (36%), Positives = 89/152 (58%), Gaps = 1/152 (0%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +++ L H N++ L+ F S E + V E +HR+++ Q +V+ Sbjct: 73 LLKHLRHENLICLQDIFLSPLED----IYFVTELQGTDLHRLLQTRPLEKQ-----FVQY 123 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNIS-YIC 357 + YQI L Y+H + GV HRD+KP N+L+N + LKICDFG A++ +P ++ Y+ Sbjct: 124 FHYQILRGLKYVH-SAGVVHRDLKPSNILINENC-DLKICDFGLARIQ---DPQMTGYVS 178 Query: 358 SRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 +RYYRAPE++ +Y +DIWSAGC+ AE+ Sbjct: 179 TRYYRAPEIMLTWQKYDVEVDIWSAGCIFAEM 210
>CDKL1_MOUSE (Q8CEQ0) Cyclin-dependent kinase-like 1 (EC 2.7.11.22)| Length = 352 Score = 99.0 bits (245), Expect = 5e-21 Identities = 54/152 (35%), Positives = 90/152 (59%), Gaps = 1/152 (0%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 M++ L HPN+V+L F + + L+LV EY H V+ ++ + +P VK Sbjct: 54 MLKQLKHPNLVNLLEVF-----RRKRRLHLVFEYCD---HTVLHELDRYQRGVPEPLVKN 105 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLV-KGEPNISYIC 357 ++Q A+ + H+ HRD+KP+N+L+ + +K+CDFG A++L G+ Y+ Sbjct: 106 ITWQTLQAVNFCHKH-NCIHRDVKPENILITKQS-AIKLCDFGFARLLTGPGDYYTDYVA 163 Query: 358 SRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 +R+YR+PEL+ G T+Y +D+W+ GCV AEL Sbjct: 164 TRWYRSPELLVGDTQYGPPVDVWAIGCVFAEL 195
>HOG1_YEAST (P32485) Mitogen-activated protein kinase HOG1 (EC 2.7.11.24) (MAP| kinase HOG1) (Osmosensing protein HOG1) Length = 435 Score = 99.0 bits (245), Expect = 5e-21 Identities = 56/152 (36%), Positives = 89/152 (58%), Gaps = 1/152 (0%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +++ L H N++ L+ F S E + V E +HR+++ Q +V+ Sbjct: 73 LLKHLRHENLICLQDIFLSPLED----IYFVTELQGTDLHRLLQTRPLEKQ-----FVQY 123 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNIS-YIC 357 + YQI L Y+H + GV HRD+KP N+L+N + LKICDFG A++ +P ++ Y+ Sbjct: 124 FLYQILRGLKYVH-SAGVIHRDLKPSNILINENC-DLKICDFGLARIQ---DPQMTGYVS 178 Query: 358 SRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 +RYYRAPE++ +Y +DIWSAGC+ AE+ Sbjct: 179 TRYYRAPEIMLTWQKYDVEVDIWSAGCIFAEM 210
>CDKL4_HUMAN (Q5MAI5) Cyclin-dependent kinase-like 4 (EC 2.7.11.22)| Length = 315 Score = 99.0 bits (245), Expect = 5e-21 Identities = 58/153 (37%), Positives = 93/153 (60%), Gaps = 2/153 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETV-HRVIRHYNKMNQRMPLIYVK 177 M++ L HPN+V+L F + + ++LV EY T+ + + R+ N + + +K Sbjct: 54 MLKQLKHPNLVNLIEVF-----RRKRKMHLVFEYCDHTLLNELERNPNGVADGV----IK 104 Query: 178 LYSYQICXALAYIHRTVGVC-HRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYI 354 +Q AL + H + C HRDIKP+N+L+ +KICDFG A++L+ G+ Y+ Sbjct: 105 SVLWQTLQALNFCH--IHNCIHRDIKPENILITKQGI-IKICDFGFAQILIPGDAYTDYV 161 Query: 355 CSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 +R+YRAPEL+ G T+Y +++DIW+ GCV AEL Sbjct: 162 ATRWYRAPELLVGDTQYGSSVDIWAIGCVFAEL 194
>CDC2D_ANTMA (Q38775) Cell division control protein 2 homolog D (EC 2.7.11.22)| (EC 2.7.11.23) Length = 312 Score = 99.0 bits (245), Expect = 5e-21 Identities = 55/153 (35%), Positives = 87/153 (56%), Gaps = 2/153 (1%) Frame = +1 Query: 1 MMRLLDH-PNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVK 177 ++R+L P+VV L ++ + L LV EY+ + + IR + + + + + VK Sbjct: 64 LLRMLSRDPHVVRLLDVKQGQNKEGKTVLYLVFEYMDTDLKKYIRSFKQTGESIAPMNVK 123 Query: 178 LYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY-I 354 YQ+C +A+ H GV HRD+KP NLL++ T LKI D G A+ ++ I Sbjct: 124 SLMYQLCKGVAFCHGH-GVLHRDLKPHNLLMDRKTMMLKIADLGLARAYTLPIKKYTHEI 182 Query: 355 CSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + +YRAPE++ GAT Y+ A+D+WS C+ AEL Sbjct: 183 LTLWYRAPEVLLGATHYSPAVDMWSVACIFAEL 215
>KSS1_YEAST (P14681) Mitogen-activated protein kinase KSS1 (EC 2.7.11.24) (MAP| kinase KSS1) (Kinase suppressor of SST2) Length = 368 Score = 98.2 bits (243), Expect = 8e-21 Identities = 57/154 (37%), Positives = 86/154 (55%), Gaps = 8/154 (5%) Frame = +1 Query: 16 DHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKLYSYQI 195 +H N++S+ + + LV E + + +VI + N + +V+ ++YQI Sbjct: 68 EHENIISILDKVRPVSIDKLNAVYLVEELMETDLQKVINNQNSGFSTLSDDHVQYFTYQI 127 Query: 196 CXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPN--------ISY 351 AL IH + V HRDIKP NLL+N + LK+CDFG A+ L + Y Sbjct: 128 LRALKSIH-SAQVIHRDIKPSNLLLNSNC-DLKVCDFGLARCLASSSDSRETLVGFMTEY 185 Query: 352 ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + +R+YRAPE++ EYTTA+DIWS GC+LAE+ Sbjct: 186 VATRWYRAPEIMLTFQEYTTAMDIWSCGCILAEM 219
>HOG1_ASHGO (Q750A9) Mitogen-activated protein kinase HOG1 (EC 2.7.11.24) (MAP| kinase HOG1) Length = 447 Score = 98.2 bits (243), Expect = 8e-21 Identities = 55/152 (36%), Positives = 89/152 (58%), Gaps = 1/152 (0%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +++ L H N++ L+ F S E + V E +HR+++ Q +++ Sbjct: 73 LLKHLRHENLICLEDIFLSPLED----IYFVTELQGTDLHRLLQTRPLEKQ-----FLQY 123 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNIS-YIC 357 + YQI L Y+H + GV HRD+KP N+L+N + LKICDFG A++ +P ++ Y+ Sbjct: 124 FLYQILRGLKYVH-SAGVIHRDLKPSNILINENC-DLKICDFGLARIQ---DPQMTGYVS 178 Query: 358 SRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 +RYYRAPE++ +Y +DIWSAGC+ AE+ Sbjct: 179 TRYYRAPEIMLTWQKYNVEVDIWSAGCIFAEM 210
>MAK_MOUSE (Q04859) Serine/threonine-protein kinase MAK (EC 2.7.11.22) (Male| germ cell-associated kinase) (Protein kinase RCK) Length = 622 Score = 98.2 bits (243), Expect = 8e-21 Identities = 56/151 (37%), Positives = 91/151 (60%), Gaps = 1/151 (0%) Frame = +1 Query: 4 MRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKLY 183 ++ L+H NV+ LK E D L+ V EY+ E ++++++ NK+ P ++ Sbjct: 54 LKKLNHANVIKLKEVI---RENDHLYF--VFEYMKENLYQLMKDRNKL---FPESVIRNI 105 Query: 184 SYQICXALAYIHRTVGVCHRDIKPQNLL-VNPHTHQLKICDFGSAKVLVKGEPNISYICS 360 YQI LA+IH+ G HRD+KP+NLL + P +KI DFG A+ L P Y+ + Sbjct: 106 MYQILQGLAFIHKH-GFFHRDMKPENLLCMGPEL--VKIADFGLARELRSQPPYTDYVST 162 Query: 361 RYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 R+YRAPE++ ++ Y++ ID+W+ G ++AEL Sbjct: 163 RWYRAPEVLLRSSVYSSPIDVWAVGSIMAEL 193
>MAK_HUMAN (P20794) Serine/threonine-protein kinase MAK (EC 2.7.11.22) (Male| germ cell-associated kinase) Length = 623 Score = 97.8 bits (242), Expect = 1e-20 Identities = 55/151 (36%), Positives = 91/151 (60%), Gaps = 1/151 (0%) Frame = +1 Query: 4 MRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKLY 183 ++ L+H NV+ LK E D L+ + EY+ E ++++++ NK+ P ++ Sbjct: 54 LKKLNHANVIKLKEVI---RENDHLYF--IFEYMKENLYQLMKDRNKL---FPESVIRNI 105 Query: 184 SYQICXALAYIHRTVGVCHRDIKPQNLL-VNPHTHQLKICDFGSAKVLVKGEPNISYICS 360 YQI LA+IH+ G HRD+KP+NLL + P +KI DFG A+ L P Y+ + Sbjct: 106 MYQILQGLAFIHKH-GFFHRDMKPENLLCMGPEL--VKIADFGLARELRSQPPYTDYVST 162 Query: 361 RYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 R+YRAPE++ ++ Y++ ID+W+ G ++AEL Sbjct: 163 RWYRAPEVLLRSSVYSSPIDVWAVGSIMAEL 193
>HOG1_ZYGRO (O93982) Mitogen-activated protein kinase HOG1 (EC 2.7.11.24) (MAP| kinase HOG1) Length = 380 Score = 97.8 bits (242), Expect = 1e-20 Identities = 55/152 (36%), Positives = 89/152 (58%), Gaps = 1/152 (0%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +++ L H N++ L+ F S E + V E +HR+++ Q +V+ Sbjct: 73 LLKHLRHENLICLQDIFLSPLED----IYFVTELQGTDLHRLLQTRPLEKQ-----FVQY 123 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNIS-YIC 357 + YQI L Y+H + GV HRD+KP N+L+N + LKICDFG A++ +P ++ Y+ Sbjct: 124 FLYQILRGLKYVH-SAGVIHRDLKPSNILINENC-DLKICDFGLARIQ---DPQMTGYVS 178 Query: 358 SRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 +RYYRAPE++ +Y +DIWSAGC+ +E+ Sbjct: 179 TRYYRAPEIMLTWQKYDVEVDIWSAGCIFSEM 210
>MAK_RAT (P20793) Serine/threonine-protein kinase MAK (EC 2.7.11.22) (Male| germ cell-associated kinase) Length = 622 Score = 97.8 bits (242), Expect = 1e-20 Identities = 55/151 (36%), Positives = 91/151 (60%), Gaps = 1/151 (0%) Frame = +1 Query: 4 MRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKLY 183 ++ L+H NV+ LK E D L+ + EY+ E ++++++ NK+ P ++ Sbjct: 54 LKKLNHANVIKLKEVI---RENDHLYF--IFEYMKENLYQLMKDRNKL---FPESVIRNI 105 Query: 184 SYQICXALAYIHRTVGVCHRDIKPQNLL-VNPHTHQLKICDFGSAKVLVKGEPNISYICS 360 YQI LA+IH+ G HRD+KP+NLL + P +KI DFG A+ L P Y+ + Sbjct: 106 MYQILQGLAFIHKH-GFFHRDMKPENLLCMGPEL--VKIADFGLARELRSQPPYTDYVST 162 Query: 361 RYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 R+YRAPE++ ++ Y++ ID+W+ G ++AEL Sbjct: 163 RWYRAPEVLLRSSVYSSPIDVWAVGSIMAEL 193
>MAPK_PETHY (Q40884) Mitogen-activated protein kinase homolog 1 (EC 2.7.11.24)| (PMEK1) Length = 384 Score = 97.4 bits (241), Expect = 1e-20 Identities = 53/152 (34%), Positives = 87/152 (57%), Gaps = 1/152 (0%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 ++R L H NV++LK + + LV E + +H++I K +Q + + + Sbjct: 82 LLRHLRHENVIALKDVMMPIQRRSFKDVYLVYELMDTDLHQII----KSSQTLSNDHCQY 137 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLV-KGEPNISYIC 357 + +Q+ L Y+H + + HRD+KP NLL+N + LKICDFG A+ K + Y+ Sbjct: 138 FLFQLLRGLKYLH-SANILHRDLKPGNLLINANC-DLKICDFGLARTSSGKDQFMTEYVV 195 Query: 358 SRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 +R+YRAPEL+ Y T+ID+WS GC+ A++ Sbjct: 196 TRWYRAPELLLCCDNYGTSIDVWSVGCIFADV 227
>CPK1_CRYNE (Q8NK05) Mitogen-activated protein kinase CPK1 (EC 2.7.11.24)| (Stress-activated protein kinase CPK1) Length = 366 Score = 97.4 bits (241), Expect = 1e-20 Identities = 61/162 (37%), Positives = 89/162 (54%), Gaps = 11/162 (6%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELF--LNLVLEYVPETVHRVIRHYNKMNQRMPLIYV 174 ++R H N++S+ E E+F + LV E + +HRVIR +Q + + Sbjct: 65 LLRHFHHENIISILDLI--QPESYEVFNEVYLVQELMETDLHRVIR-----SQELSDDHC 117 Query: 175 KLYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNIS-- 348 + + YQ L +H + V HRD+KP NLL+N + LKICDFG A+ K P S Sbjct: 118 QYFVYQTLRGLKALH-SADVLHRDLKPSNLLLNANC-DLKICDFGLARSSAKPPPGTSDG 175 Query: 349 -------YICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 Y+ +R+YRAPE++ EYT AID+WS GC+LAE+ Sbjct: 176 GQGFMTEYVATRWYRAPEVMLSFQEYTKAIDLWSVGCILAEM 217
>NLK_MOUSE (O54949) Serine/threonine kinase NLK (EC 2.7.11.24) (Nemo-like| kinase) Length = 515 Score = 97.4 bits (241), Expect = 1e-20 Identities = 54/124 (43%), Positives = 77/124 (62%), Gaps = 2/124 (1%) Frame = +1 Query: 88 LVLEYVPETVHRVIRHYNKMNQRMPLIYVKLYSYQICXALAYIHRTVGVCHRDIKPQNLL 267 +V E + +H++I Q + +VK++ YQI L Y+H + G+ HRDIKP NLL Sbjct: 205 VVTELMQSDLHKII----VSPQPLSSDHVKVFLYQILRGLKYLH-SAGILHRDIKPGNLL 259 Query: 268 VNPHTHQLKICDFGSAKV--LVKGEPNISYICSRYYRAPELIFGATEYTTAIDIWSAGCV 441 VN + LKICDFG A+V L + + ++YYRAPE++ G+ Y+ AIDIWS GC+ Sbjct: 260 VNSNC-VLKICDFGLARVEELDESRHMTQEVVTQYYRAPEILMGSRHYSNAIDIWSVGCI 318 Query: 442 LAEL 453 AEL Sbjct: 319 FAEL 322
>NLK_HUMAN (Q9UBE8) Serine/threonine kinase NLK (EC 2.7.11.24) (Nemo-like| kinase) (LAK1 protein) Length = 515 Score = 97.4 bits (241), Expect = 1e-20 Identities = 54/124 (43%), Positives = 77/124 (62%), Gaps = 2/124 (1%) Frame = +1 Query: 88 LVLEYVPETVHRVIRHYNKMNQRMPLIYVKLYSYQICXALAYIHRTVGVCHRDIKPQNLL 267 +V E + +H++I Q + +VK++ YQI L Y+H + G+ HRDIKP NLL Sbjct: 205 VVTELMQSDLHKII----VSPQPLSSDHVKVFLYQILRGLKYLH-SAGILHRDIKPGNLL 259 Query: 268 VNPHTHQLKICDFGSAKV--LVKGEPNISYICSRYYRAPELIFGATEYTTAIDIWSAGCV 441 VN + LKICDFG A+V L + + ++YYRAPE++ G+ Y+ AIDIWS GC+ Sbjct: 260 VNSNC-VLKICDFGLARVEELDESRHMTQEVVTQYYRAPEILMGSRHYSNAIDIWSVGCI 318 Query: 442 LAEL 453 AEL Sbjct: 319 FAEL 322
>YRL5_CAEEL (Q09595) Putative serine/threonine-protein kinase R03D7.5 (EC| 2.7.11.1) Length = 410 Score = 96.3 bits (238), Expect = 3e-20 Identities = 54/148 (36%), Positives = 91/148 (61%), Gaps = 1/148 (0%) Frame = +1 Query: 13 LDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKLYSYQ 192 L HP + +L + F+S D++ LVL+Y+P+ + R+ + ++ KLY++Q Sbjct: 82 LFHPAISNLLY-FYSRNANDKVINCLVLDYLPQDLARL----RDQGVKFDVLDAKLYTFQ 136 Query: 193 ICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNIS-YICSRYY 369 + A++++ + + H DIKPQN++++ +LK+ DFG+A+ L E S Y +R+Y Sbjct: 137 LFCAISHL-TSKNIVHMDIKPQNVVMDRMAGRLKLADFGNARRLETNEKTGSAYQVTRFY 195 Query: 370 RAPELIFGATEYTTAIDIWSAGCVLAEL 453 R PEL+FG ++T +IDIWSA CV EL Sbjct: 196 RPPELLFGCEKFTASIDIWSATCVAFEL 223
>MAPK_FUSSO (Q00859) Mitogen-activated protein kinase (EC 2.7.11.24) (FsMAPK)| Length = 355 Score = 95.9 bits (237), Expect = 4e-20 Identities = 55/155 (35%), Positives = 85/155 (54%), Gaps = 4/155 (2%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 ++R +H N++S+ + + L+ E + +HR IR Q + + + Sbjct: 72 LLRYFNHENIISILDIQKPRNYESFNEVYLIQELMETDMHRAIR-----TQDLSDDHCQY 126 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPN----IS 348 + YQ AL +H + V HRD+KP NLL+N + LK+CDFG A+ E N Sbjct: 127 FIYQTLRALKAMH-SANVLHRDLKPSNLLLNANC-DLKVCDFGLARSAASQEDNSGFMTE 184 Query: 349 YICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 Y+ +R+YRAPE++ EYT AID+WS GC+LAE+ Sbjct: 185 YVATRWYRAPEIMLTFKEYTKAIDVWSVGCILAEM 219
>MK07_MOUSE (Q9WVS8) Mitogen-activated protein kinase 7 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 5) (ERK-5) (BMK1 kinase) Length = 806 Score = 95.9 bits (237), Expect = 4e-20 Identities = 55/157 (35%), Positives = 88/157 (56%), Gaps = 6/157 (3%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDEL-FLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVK 177 +++ H N++++K T E + +VL+ + +H++I +Q + L +V+ Sbjct: 105 ILKHFKHDNIIAIKDILKPTVPYGEFRSVYVVLDLMESDLHQIIHS----SQPLTLEHVR 160 Query: 178 LYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPN----- 342 + YQ+ L Y+H + V HRD+KP NLLVN + +LKI DFG A+ L Sbjct: 161 YFLYQLLRGLKYMH-SAQVIHRDLKPSNLLVNENC-ELKIGDFGMARGLCTSPAEHQYFM 218 Query: 343 ISYICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 Y+ +R+YRAPEL+ EYT AID+WS GC+ E+ Sbjct: 219 TEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEM 255
>CDK2_CARAU (P43450) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 95.9 bits (237), Expect = 4e-20 Identities = 59/154 (38%), Positives = 90/154 (58%), Gaps = 3/154 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +++ L+HPN+V L H T K L LV E++ + + R + +PL VK Sbjct: 54 LLKELNHPNIVKL-HDVIHTENK----LYLVFEFLHQDLKRFMDSSTVTGISLPL--VKS 106 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY--- 351 Y +Q+ LA+ H + V HRD+KPQNLL+N ++K+ DFG A+ G P +Y Sbjct: 107 YLFQLLQGLAFCH-SHRVLHRDLKPQNLLINAQG-EIKLADFGLARAF--GVPVRTYTHE 162 Query: 352 ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + + +YRAPE++ G Y+TA+DIWS GC+ AE+ Sbjct: 163 VVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEM 196
>CDKL1_BRARE (Q6AXJ9) Cyclin-dependent kinase-like 1 (EC 2.7.11.22)| Length = 350 Score = 95.9 bits (237), Expect = 4e-20 Identities = 54/152 (35%), Positives = 87/152 (57%), Gaps = 1/152 (0%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 M++ L HPN+V+L F + + L+LV EY H V+ ++ + +P VK Sbjct: 54 MLKQLKHPNLVNLMEVF-----RRKRKLHLVFEYCD---HTVLNELDRYPRGVPEHMVKS 105 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKG-EPNISYIC 357 +Q A+ + H+ HRD+KP+N+L+ H +K+CDFG A++L + + Sbjct: 106 IIWQTLQAVNFCHKQ-NCIHRDVKPENILITKH-QVIKLCDFGFARILTGPCDYYTDCVA 163 Query: 358 SRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 +R+YRAPEL+ G T+Y +D+W+ GCV AEL Sbjct: 164 TRWYRAPELLVGDTQYGPPVDVWAVGCVFAEL 195
>MK07_HUMAN (Q13164) Mitogen-activated protein kinase 7 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 5) (ERK-5) (ERK4) (BMK1 kinase) Length = 815 Score = 95.9 bits (237), Expect = 4e-20 Identities = 55/157 (35%), Positives = 88/157 (56%), Gaps = 6/157 (3%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDEL-FLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVK 177 +++ H N++++K T E + +VL+ + +H++I +Q + L +V+ Sbjct: 104 ILKHFKHDNIIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQIIHS----SQPLTLEHVR 159 Query: 178 LYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPN----- 342 + YQ+ L Y+H + V HRD+KP NLLVN + +LKI DFG A+ L Sbjct: 160 YFLYQLLRGLKYMH-SAQVIHRDLKPSNLLVNENC-ELKIGDFGMARGLCTSPAEHQYFM 217 Query: 343 ISYICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 Y+ +R+YRAPEL+ EYT AID+WS GC+ E+ Sbjct: 218 TEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEM 254
>PCTK3_RAT (O35832) Serine/threonine-protein kinase PCTAIRE-3 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 3) Length = 451 Score = 95.5 bits (236), Expect = 5e-20 Identities = 56/154 (36%), Positives = 89/154 (57%), Gaps = 3/154 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +++ L H N+V+L H T L LV EY+ + + + H + M + VK+ Sbjct: 170 LLKDLKHANIVTL-HDLIHTDRS----LTLVFEYLDSDLKQYLDHCGNL---MNMHNVKI 221 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY--- 351 + +Q+ LAY HR + HRD+KPQNLL+N +LK+ DFG A+ K P +Y Sbjct: 222 FMFQLLRGLAYCHRRK-ILHRDLKPQNLLINERG-ELKLADFGLARA--KSVPTKTYSNE 277 Query: 352 ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + + +YR P+++ G+TEY+T ID+W GC+L E+ Sbjct: 278 VVTLWYRPPDVLLGSTEYSTPIDMWGVGCILYEM 311
>CD2L6_HUMAN (Q9BWU1) Cell division cycle 2-like protein kinase 6 (EC 2.7.11.22)| (CDC2-related protein kinase 6) (Death-preventing kinase) (Cyclin-dependent kinase 11) Length = 502 Score = 95.1 bits (235), Expect = 7e-20 Identities = 57/163 (34%), Positives = 90/163 (55%), Gaps = 12/163 (7%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHY-----NKMNQRMPL 165 ++R L HPNV++L+ F S +++ + L+ +Y + +I+ + NK ++P Sbjct: 69 LLRELKHPNVIALQKVFLSHSDRK---VWLLFDYAEHDLWHIIKFHRASKANKKPMQLPR 125 Query: 166 IYVKLYSYQICXALAYIHRTVGVCHRDIKPQNLLV---NPHTHQLKICDFGSAKVLVKGE 336 VK YQI + Y+H V HRD+KP N+LV P ++KI D G A++ Sbjct: 126 SMVKSLLYQILDGIHYLHAN-WVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPL 184 Query: 337 PNIS----YICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 ++ + + +YRAPEL+ GA YT AIDIW+ GC+ AEL Sbjct: 185 KPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAEL 227
>CD2L6_MOUSE (Q8BWD8) Cell division cycle 2-like protein kinase 6 (EC 2.7.11.22)| (CDC2-related protein kinase 6) Length = 501 Score = 95.1 bits (235), Expect = 7e-20 Identities = 57/163 (34%), Positives = 90/163 (55%), Gaps = 12/163 (7%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHY-----NKMNQRMPL 165 ++R L HPNV++L+ F S +++ + L+ +Y + +I+ + NK ++P Sbjct: 69 LLRELKHPNVIALQKVFLSHSDRK---VWLLFDYAEHDLWHIIKFHRASKANKKPMQLPR 125 Query: 166 IYVKLYSYQICXALAYIHRTVGVCHRDIKPQNLLV---NPHTHQLKICDFGSAKVLVKGE 336 VK YQI + Y+H V HRD+KP N+LV P ++KI D G A++ Sbjct: 126 SMVKSLLYQILDGIHYLHAN-WVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPL 184 Query: 337 PNIS----YICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 ++ + + +YRAPEL+ GA YT AIDIW+ GC+ AEL Sbjct: 185 KPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAEL 227
>MK03_HUMAN (P27361) Mitogen-activated protein kinase 3 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 1) (ERK-1) (Insulin-stimulated MAP2 kinase) (MAP kinase 1) (MAPK 1) (p44-ERK1) (ERT2) (p44-MAPK) (Microtubule-associated protein 2 kinase) Length = 379 Score = 94.4 bits (233), Expect = 1e-19 Identities = 51/149 (34%), Positives = 88/149 (59%), Gaps = 4/149 (2%) Frame = +1 Query: 19 HPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKLYSYQIC 198 H NV+ ++ ++T + + +V + + ++++++ +Q++ ++ + YQI Sbjct: 97 HENVIGIRDILRASTLEAMRDVYIVQDLMETDLYKLLK-----SQQLSNDHICYFLYQIL 151 Query: 199 XALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNIS----YICSRY 366 L YIH + V HRD+KP NLL+N T LKICDFG A++ + Y+ +R+ Sbjct: 152 RGLKYIH-SANVLHRDLKPSNLLINT-TCDLKICDFGLARIADPEHDHTGFLTEYVATRW 209 Query: 367 YRAPELIFGATEYTTAIDIWSAGCVLAEL 453 YRAPE++ + YT +IDIWS GC+LAE+ Sbjct: 210 YRAPEIMLNSKGYTKSIDIWSVGCILAEM 238
>CDK8_HUMAN (P49336) Cell division protein kinase 8 (EC 2.7.11.22) (EC| 2.7.11.23) (Protein kinase K35) Length = 464 Score = 94.4 bits (233), Expect = 1e-19 Identities = 58/163 (35%), Positives = 89/163 (54%), Gaps = 12/163 (7%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHY-----NKMNQRMPL 165 ++R L HPNV+SL+ F S ++ + L+ +Y + +I+ + NK ++P Sbjct: 69 LLRELKHPNVISLQKVFLSHADRK---VWLLFDYAEHDLWHIIKFHRASKANKKPVQLPR 125 Query: 166 IYVKLYSYQICXALAYIHRTVGVCHRDIKPQNLLV---NPHTHQLKICDFGSAKVLVKGE 336 VK YQI + Y+H V HRD+KP N+LV P ++KI D G A++ Sbjct: 126 GMVKSLLYQILDGIHYLHAN-WVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPL 184 Query: 337 PNIS----YICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 ++ + + +YRAPEL+ GA YT AIDIW+ GC+ AEL Sbjct: 185 KPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAEL 227
>KIN28_YEAST (P06242) Serine/threonine-protein kinase KIN28 (EC 2.7.11.23)| Length = 306 Score = 93.6 bits (231), Expect = 2e-19 Identities = 57/148 (38%), Positives = 83/148 (56%), Gaps = 1/148 (0%) Frame = +1 Query: 13 LDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKLYSYQ 192 + HPNV+ L F + LNLVLE++P + VI+ + + +K + Sbjct: 61 MQHPNVIELIDIFMAYDN-----LNLVLEFLPTDLEVVIKDKSILFTPAD---IKAWMLM 112 Query: 193 ICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVL-VKGEPNISYICSRYY 369 + + HR + HRD+KP NLL +P Q+K+ DFG A+ + E S + +R+Y Sbjct: 113 TLRGVYHCHRNF-ILHRDLKPNNLLFSPDG-QIKVADFGLARAIPAPHEILTSNVVTRWY 170 Query: 370 RAPELIFGATEYTTAIDIWSAGCVLAEL 453 RAPEL+FGA YT+AIDIWS G + AEL Sbjct: 171 RAPELLFGAKHYTSAIDIWSVGVIFAEL 198
>SPK1_SCHPO (P27638) Mitogen-activated protein kinase spk1 (EC 2.7.11.24) (MAP| kinase spk1) (MAPK) Length = 372 Score = 93.6 bits (231), Expect = 2e-19 Identities = 55/155 (35%), Positives = 90/155 (58%), Gaps = 4/155 (2%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 ++R H N++S+ + ++ + +V E + ++RVIR +Q + + + Sbjct: 88 LLRHFRHENIISILDILPPPSYQELEDVYIVQELMETDLYRVIR-----SQPLSDDHCQY 142 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVK--GEPNI--S 348 ++YQI AL +H + GV HRD+KP NLL+N + LK+ DFG A+ G P Sbjct: 143 FTYQILRALKAMH-SAGVVHRDLKPSNLLLNANC-DLKVADFGLARSTTAQGGNPGFMTE 200 Query: 349 YICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 Y+ +R+YRAPE++ EY+ AID+WS GC+LAE+ Sbjct: 201 YVATRWYRAPEIMLSFREYSKAIDLWSTGCILAEM 235
>MK03_RAT (P21708) Mitogen-activated protein kinase 3 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 1) (ERK-1) (Insulin-stimulated MAP2 kinase) (MAP kinase 1) (MAPK 1) (p44-ERK1) (ERT2) (p44-MAPK) (Microtubule-associated protein 2 kinase) (MNK1) Length = 380 Score = 93.6 bits (231), Expect = 2e-19 Identities = 51/149 (34%), Positives = 87/149 (58%), Gaps = 4/149 (2%) Frame = +1 Query: 19 HPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKLYSYQIC 198 H NV+ ++ + T + + +V + + ++++++ +Q++ ++ + YQI Sbjct: 98 HENVIGIRDILRAPTLEAMRDVYIVQDLMETDLYKLLK-----SQQLSNDHICYFLYQIL 152 Query: 199 XALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNIS----YICSRY 366 L YIH + V HRD+KP NLL+N T LKICDFG A++ + Y+ +R+ Sbjct: 153 RGLKYIH-SANVLHRDLKPSNLLINT-TCDLKICDFGLARIADPEHDHTGFLTEYVATRW 210 Query: 367 YRAPELIFGATEYTTAIDIWSAGCVLAEL 453 YRAPE++ + YT +IDIWS GC+LAE+ Sbjct: 211 YRAPEIMLNSKGYTKSIDIWSVGCILAEM 239
>MK03_MOUSE (Q63844) Mitogen-activated protein kinase 3 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 1) (ERK-1) (Insulin-stimulated MAP2 kinase) (MAP kinase 1) (MAPK 1) (p44-ERK1) (ERT2) (p44-MAPK) (Microtubule-associated protein 2 kinase) (MNK1) Length = 380 Score = 93.6 bits (231), Expect = 2e-19 Identities = 51/149 (34%), Positives = 87/149 (58%), Gaps = 4/149 (2%) Frame = +1 Query: 19 HPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKLYSYQIC 198 H NV+ ++ + T + + +V + + ++++++ +Q++ ++ + YQI Sbjct: 98 HENVIGIRDILRAPTLEAMRDVYIVQDLMETDLYKLLK-----SQQLSNDHICYFLYQIL 152 Query: 199 XALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNIS----YICSRY 366 L YIH + V HRD+KP NLL+N T LKICDFG A++ + Y+ +R+ Sbjct: 153 RGLKYIH-SANVLHRDLKPSNLLINT-TCDLKICDFGLARIADPEHDHTGFLTEYVATRW 210 Query: 367 YRAPELIFGATEYTTAIDIWSAGCVLAEL 453 YRAPE++ + YT +IDIWS GC+LAE+ Sbjct: 211 YRAPEIMLNSKGYTKSIDIWSVGCILAEM 239
>PCTK3_MOUSE (Q04899) Serine/threonine-protein kinase PCTAIRE-3 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 3) Length = 451 Score = 93.6 bits (231), Expect = 2e-19 Identities = 55/154 (35%), Positives = 88/154 (57%), Gaps = 3/154 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +++ L H N+V+L H T L LV EY+ + + + H + M + VK+ Sbjct: 170 LLKDLKHANIVTL-HDLIHTDRS----LTLVFEYLDSDLKQYLDHCGNL---MNMHNVKI 221 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY--- 351 + +Q+ LAY H + HRD+KPQNLL+N +LK+ DFG A+ K P +Y Sbjct: 222 FMFQLLRGLAYCHHRK-ILHRDLKPQNLLINERG-ELKLADFGLARA--KSVPTKTYSNE 277 Query: 352 ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + + +YR P+++ G+TEY+T ID+W GC+L E+ Sbjct: 278 VVTLWYRPPDVLLGSTEYSTPIDMWGVGCILYEM 311
>CDC2A_ARATH (P24100) Cell division control protein 2 homolog A (EC 2.7.11.22)| (EC 2.7.11.23) Length = 294 Score = 93.2 bits (230), Expect = 3e-19 Identities = 55/154 (35%), Positives = 89/154 (57%), Gaps = 3/154 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +++ + H N+V L+ S E L LV EY+ + + + ++ + +I K Sbjct: 54 LLKEMQHSNIVKLQDVVHS-----EKRLYLVFEYLDLDLKKHMDSTPDFSKDLHMI--KT 106 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY--- 351 Y YQI +AY H + V HRD+KPQNLL++ T+ LK+ DFG A+ G P ++ Sbjct: 107 YLYQILRGIAYCH-SHRVLHRDLKPQNLLIDRRTNSLKLADFGLARAF--GIPVRTFTHE 163 Query: 352 ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + + +YRAPE++ G+ Y+T +DIWS GC+ AE+ Sbjct: 164 VVTLWYRAPEILLGSHHYSTPVDIWSVGCIFAEM 197
>CDC2A_ANTMA (Q38772) Cell division control protein 2 homolog A (EC 2.7.11.22)| (EC 2.7.11.23) Length = 294 Score = 93.2 bits (230), Expect = 3e-19 Identities = 55/154 (35%), Positives = 90/154 (58%), Gaps = 3/154 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +++ + H N+V L+ S E L LV EY+ + + + + +Q L VK+ Sbjct: 54 LLKEMQHGNIVRLQDVVHS-----EKRLYLVFEYLDLDLKKHMDSCPEFSQDPRL--VKM 106 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY--- 351 + YQI +AY H + V HRD+KPQNLL++ T+ LK+ DFG A+ G P ++ Sbjct: 107 FLYQILRGIAYCH-SHRVLHRDLKPQNLLIDRRTNALKLADFGLARAF--GIPVRTFTHE 163 Query: 352 ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + + +YRAPE++ G+ Y+T +D+WS GC+ AE+ Sbjct: 164 VVTLWYRAPEILLGSRHYSTPVDVWSVGCIFAEM 197
>CDC2_MAIZE (P23111) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) Length = 294 Score = 92.8 bits (229), Expect = 4e-19 Identities = 55/154 (35%), Positives = 89/154 (57%), Gaps = 3/154 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +++ ++H N+V L S E + LV EY+ + + + + + LI K Sbjct: 54 LLKEMNHGNIVRLHDVVHS-----EKRIYLVFEYLDLDLKKFMDSCPEFAKNPTLI--KS 106 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY--- 351 Y YQI +AY H + V HRD+KPQNLL++ T+ LK+ DFG A+ G P ++ Sbjct: 107 YLYQILHGVAYCH-SHRVLHRDLKPQNLLIDRRTNALKLADFGLARAF--GIPVRTFTHE 163 Query: 352 ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + + +YRAPE++ GA +Y+T +D+WS GC+ AE+ Sbjct: 164 VVTLWYRAPEILLGARQYSTPVDVWSVGCIFAEM 197
>MK01_XENLA (P26696) Mitogen-activated protein kinase 1 (EC 2.7.11.24) (Myelin| xP42 protein kinase) (Myelin basic protein kinase) (MBP kinase) (M phase MAP kinase) Length = 361 Score = 92.8 bits (229), Expect = 4e-19 Identities = 51/149 (34%), Positives = 84/149 (56%), Gaps = 4/149 (2%) Frame = +1 Query: 19 HPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKLYSYQIC 198 H N++ + + T + + +V + + ++++++ + N ++ + YQI Sbjct: 83 HENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSND-----HICYFLYQIL 137 Query: 199 XALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNIS----YICSRY 366 L YIH + V HRD+KP NLL+N T LKICDFG A+V + Y+ +R+ Sbjct: 138 RGLKYIH-SANVLHRDLKPSNLLLNT-TCDLKICDFGLARVADPDHDHTGFLTEYVATRW 195 Query: 367 YRAPELIFGATEYTTAIDIWSAGCVLAEL 453 YRAPE++ + YT +IDIWS GC+LAE+ Sbjct: 196 YRAPEIMLNSKGYTKSIDIWSVGCILAEM 224
>MK01_RAT (P63086) Mitogen-activated protein kinase 1 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 2) (ERK-2) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2) (p42-MAPK) (ERT1) Length = 357 Score = 92.8 bits (229), Expect = 4e-19 Identities = 51/149 (34%), Positives = 84/149 (56%), Gaps = 4/149 (2%) Frame = +1 Query: 19 HPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKLYSYQIC 198 H N++ + + T + + +V + + ++++++ + N ++ + YQI Sbjct: 77 HENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSND-----HICYFLYQIL 131 Query: 199 XALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNIS----YICSRY 366 L YIH + V HRD+KP NLL+N T LKICDFG A+V + Y+ +R+ Sbjct: 132 RGLKYIH-SANVLHRDLKPSNLLLNT-TCDLKICDFGLARVADPDHDHTGFLTEYVATRW 189 Query: 367 YRAPELIFGATEYTTAIDIWSAGCVLAEL 453 YRAPE++ + YT +IDIWS GC+LAE+ Sbjct: 190 YRAPEIMLNSKGYTKSIDIWSVGCILAEM 218
>MK01_MOUSE (P63085) Mitogen-activated protein kinase 1 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 2) (ERK-2) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2) (p42-MAPK) (ERT1) Length = 357 Score = 92.8 bits (229), Expect = 4e-19 Identities = 51/149 (34%), Positives = 84/149 (56%), Gaps = 4/149 (2%) Frame = +1 Query: 19 HPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKLYSYQIC 198 H N++ + + T + + +V + + ++++++ + N ++ + YQI Sbjct: 77 HENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSND-----HICYFLYQIL 131 Query: 199 XALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNIS----YICSRY 366 L YIH + V HRD+KP NLL+N T LKICDFG A+V + Y+ +R+ Sbjct: 132 RGLKYIH-SANVLHRDLKPSNLLLNT-TCDLKICDFGLARVADPDHDHTGFLTEYVATRW 189 Query: 367 YRAPELIFGATEYTTAIDIWSAGCVLAEL 453 YRAPE++ + YT +IDIWS GC+LAE+ Sbjct: 190 YRAPEIMLNSKGYTKSIDIWSVGCILAEM 218
>CDC2_CAEEL (P34556) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) Length = 332 Score = 92.8 bits (229), Expect = 4e-19 Identities = 55/154 (35%), Positives = 93/154 (60%), Gaps = 3/154 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +++ L HPNVV L+ +++ LFL + E++ + R + K ++ +PL +K Sbjct: 72 LLKELQHPNVVGLEAVIM---QENRLFL--IFEFLSFDLKRYMDQLGK-DEYLPLETLKS 125 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY--- 351 Y++QI A+ + H+ V HRD+KPQNLLV+ + +K+ DFG A+ + G P Y Sbjct: 126 YTFQILQAMCFCHQR-RVIHRDLKPQNLLVD-NNGAIKLADFGLARAI--GIPIRVYTHE 181 Query: 352 ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + + +YRAPE++ GA Y+ +D+WS GC+ AE+ Sbjct: 182 VVTLWYRAPEILMGAQRYSMGVDMWSIGCIFAEM 215
>MK01_HUMAN (P28482) Mitogen-activated protein kinase 1 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 2) (ERK-2) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2) (p42-MAPK) (ERT1) Length = 359 Score = 92.8 bits (229), Expect = 4e-19 Identities = 51/149 (34%), Positives = 84/149 (56%), Gaps = 4/149 (2%) Frame = +1 Query: 19 HPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKLYSYQIC 198 H N++ + + T + + +V + + ++++++ + N ++ + YQI Sbjct: 79 HENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSND-----HICYFLYQIL 133 Query: 199 XALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNIS----YICSRY 366 L YIH + V HRD+KP NLL+N T LKICDFG A+V + Y+ +R+ Sbjct: 134 RGLKYIH-SANVLHRDLKPSNLLLNT-TCDLKICDFGLARVADPDHDHTGFLTEYVATRW 191 Query: 367 YRAPELIFGATEYTTAIDIWSAGCVLAEL 453 YRAPE++ + YT +IDIWS GC+LAE+ Sbjct: 192 YRAPEIMLNSKGYTKSIDIWSVGCILAEM 220
>MK01_BOVIN (P46196) Mitogen-activated protein kinase 1 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 2) (ERK-2) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2) (p42-MAPK) (ERT1) Length = 359 Score = 92.8 bits (229), Expect = 4e-19 Identities = 51/149 (34%), Positives = 84/149 (56%), Gaps = 4/149 (2%) Frame = +1 Query: 19 HPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKLYSYQIC 198 H N++ + + T + + +V + + ++++++ + N ++ + YQI Sbjct: 79 HENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSND-----HICYFLYQIL 133 Query: 199 XALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNIS----YICSRY 366 L YIH + V HRD+KP NLL+N T LKICDFG A+V + Y+ +R+ Sbjct: 134 RGLKYIH-SANVLHRDLKPSNLLLNT-TCDLKICDFGLARVADPDHDHTGFLTEYVATRW 191 Query: 367 YRAPELIFGATEYTTAIDIWSAGCVLAEL 453 YRAPE++ + YT +IDIWS GC+LAE+ Sbjct: 192 YRAPEIMLNSKGYTKSIDIWSVGCILAEM 220
>PCTK2_RAT (O35831) Serine/threonine-protein kinase PCTAIRE-2 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 2) Length = 523 Score = 92.4 bits (228), Expect = 5e-19 Identities = 57/154 (37%), Positives = 89/154 (57%), Gaps = 3/154 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +++ L H N+V+L H T + L LV EY+ + + + + + M + VKL Sbjct: 241 LLKDLKHANIVTL-HDIVHTDKS----LTLVFEYLDKDLKQ---YMDDCGSIMSMHNVKL 292 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY--- 351 + YQI LAY HR V HRD+KPQNLL+N +LK+ DFG A+ K P +Y Sbjct: 293 FLYQILRGLAYCHRRK-VLHRDLKPQNLLINERG-ELKLADFGLARA--KSVPTKTYSNE 348 Query: 352 ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + + +YR P+++ G++EY+T ID+W GC+ E+ Sbjct: 349 VVTLWYRPPDVLLGSSEYSTQIDMWGVGCIFFEM 382
>PCTK2_MOUSE (Q8K0D0) Serine/threonine-protein kinase PCTAIRE-2 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 2) Length = 523 Score = 92.4 bits (228), Expect = 5e-19 Identities = 57/154 (37%), Positives = 89/154 (57%), Gaps = 3/154 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +++ L H N+V+L H T + L LV EY+ + + + + + M + VKL Sbjct: 241 LLKDLKHANIVTL-HDIVHTDKS----LTLVFEYLDKDLKQ---YMDDCGNIMSMHNVKL 292 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY--- 351 + YQI LAY HR V HRD+KPQNLL+N +LK+ DFG A+ K P +Y Sbjct: 293 FLYQILRGLAYCHRRK-VLHRDLKPQNLLINERG-ELKLADFGLARA--KSVPTKTYSNE 348 Query: 352 ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + + +YR P+++ G++EY+T ID+W GC+ E+ Sbjct: 349 VVTLWYRPPDVLLGSSEYSTQIDMWGVGCIFFEM 382
>PCTK2_HUMAN (Q00537) Serine/threonine-protein kinase PCTAIRE-2 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 2) Length = 523 Score = 92.4 bits (228), Expect = 5e-19 Identities = 57/154 (37%), Positives = 89/154 (57%), Gaps = 3/154 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +++ L H N+V+L H T + L LV EY+ + + + + + M + VKL Sbjct: 241 LLKDLKHANIVTL-HDIVHTDKS----LTLVFEYLDKDLKQ---YMDDCGNIMSMHNVKL 292 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY--- 351 + YQI LAY HR V HRD+KPQNLL+N +LK+ DFG A+ K P +Y Sbjct: 293 FLYQILRGLAYCHRRK-VLHRDLKPQNLLIN-EKGELKLADFGLARA--KSVPTKTYSNE 348 Query: 352 ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + + +YR P+++ G++EY+T ID+W GC+ E+ Sbjct: 349 VVTLWYRPPDVLLGSSEYSTQIDMWGVGCIFFEM 382
>PEF1_SCHPO (O74456) Serine/threonine-protein kinase pef1 (EC 2.7.11.22)| (Cyclin-dependent kinase pef1) (PHO85 homolog) Length = 288 Score = 92.4 bits (228), Expect = 5e-19 Identities = 55/154 (35%), Positives = 92/154 (59%), Gaps = 3/154 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +M+ L HPN++SL S + E L LV EY+ + + + + Y +P VK Sbjct: 52 LMKELRHPNIMSL-----SDVLQTENKLMLVFEYMEKDLKKYMDTYGNQGA-LPPSQVKN 105 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY--- 351 ++ Q+ +++ H V HRD+KPQNLL+N +LK+ DFG A+ + G P ++ Sbjct: 106 FTQQLLKGISFCHEN-RVLHRDLKPQNLLINSRG-ELKLADFGLARSI--GIPVNTFSNE 161 Query: 352 ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + + +YRAP+++ G+ Y+T+IDIWS GC++AE+ Sbjct: 162 VVTLWYRAPDVLLGSRVYSTSIDIWSVGCIMAEM 195
>CDKL3_MOUSE (Q8BLF2) Cyclin-dependent kinase-like 3 (EC 2.7.11.22)| Length = 595 Score = 92.0 bits (227), Expect = 6e-19 Identities = 52/146 (35%), Positives = 84/146 (57%), Gaps = 1/146 (0%) Frame = +1 Query: 19 HPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKLYSYQIC 198 H N+V+L F + + ++LV E++ TV ++HY + L + Y +QI Sbjct: 59 HENLVNLIEVF-----RQKKKIHLVFEFIDHTVLDELQHYCHGLESKRL---RKYLFQIL 110 Query: 199 XALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVK-GEPNISYICSRYYRA 375 A+ Y+H + HRDIKP+N+LV+ + K+CDFG A+ L G+ Y+ +R+YRA Sbjct: 111 RAIEYLHNN-NIIHRDIKPENILVS-QSGITKLCDFGFARTLAAPGDVYTDYVATRWYRA 168 Query: 376 PELIFGATEYTTAIDIWSAGCVLAEL 453 PEL+ T Y +DIW+ GC++ E+ Sbjct: 169 PELVLKDTSYGKPVDIWALGCMIIEM 194
>PHO85_CANAL (Q9HGY5) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) (CaPHO85) Length = 326 Score = 92.0 bits (227), Expect = 6e-19 Identities = 54/154 (35%), Positives = 92/154 (59%), Gaps = 3/154 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +M+ LDH N+V+L + + L LV EY+ + + + + + + + + L VK Sbjct: 57 LMKELDHENIVTLYDVIHTENK-----LTLVFEYMDKDLKKYMEVHGQQSA-LDLKVVKS 110 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY--- 351 + +Q+ + + H V HRD+KPQNLL+N + +LK+ DFG A+ G P ++ Sbjct: 111 FMFQLLKGIMFCHDN-RVLHRDLKPQNLLIN-NKGELKLGDFGLARAF--GIPFNTFSNE 166 Query: 352 ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + + +YRAP+++ G+ YTT+IDIWSAGC+ AE+ Sbjct: 167 VVTLWYRAPDVLLGSRAYTTSIDIWSAGCIFAEM 200
>ERK1_DICDI (P42525) Extracellular signal-regulated kinase 1 (EC 2.7.11.24)| (ERK1) (MAP kinase 1) Length = 415 Score = 92.0 bits (227), Expect = 6e-19 Identities = 53/153 (34%), Positives = 84/153 (54%), Gaps = 2/153 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 ++R H N++S+K +++ + +V E + +H++I ++ + + Sbjct: 81 LLRHFKHENLISIKDILKPNSKEQFEDVYIVSELMDTDLHQIITSPQPLSDD----HCQY 136 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNI--SYI 354 + YQ+ L +IH + V HRD+KP NLL+N LKICD G A+V Y+ Sbjct: 137 FVYQMLRGLKHIH-SANVLHRDLKPSNLLINEDC-LLKICDLGLARVEDATHQGFMTEYV 194 Query: 355 CSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 +R+YRAPE+I +YT AIDIWS GC+ AEL Sbjct: 195 ATRWYRAPEVILSWNKYTKAIDIWSVGCIFAEL 227
>SUR1_CAEEL (P39745) Mitogen-activated protein kinase mpk-1 (EC 2.7.11.24) (MAP| kinase sur-1) Length = 444 Score = 92.0 bits (227), Expect = 6e-19 Identities = 52/149 (34%), Positives = 85/149 (57%), Gaps = 4/149 (2%) Frame = +1 Query: 19 HPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKLYSYQIC 198 H N+++++ S T + +V + ++++++ Q++ +V + YQI Sbjct: 151 HENIINIQEIIRSETVDSLKDIYIVQCLMETDLYKLLK-----TQKLSNDHVCYFLYQIL 205 Query: 199 XALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNIS----YICSRY 366 L YIH + V HRD+KP NLL+N T LKICDFG A+V + Y+ +R+ Sbjct: 206 RGLKYIH-SANVLHRDLKPSNLLLNT-TCDLKICDFGLARVTDPQTDHTGFLTEYVATRW 263 Query: 367 YRAPELIFGATEYTTAIDIWSAGCVLAEL 453 YRAPE++ + YT +ID+WS GC+LAE+ Sbjct: 264 YRAPEIMLNSKGYTKSIDVWSVGCILAEM 292
>PHO85_KLULA (Q92241) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 304 Score = 91.7 bits (226), Expect = 8e-19 Identities = 53/154 (34%), Positives = 88/154 (57%), Gaps = 3/154 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQR--MPLIYV 174 +M+ L H N+V L + + L LV E++ + + + + NK N + + V Sbjct: 56 LMKELKHDNIVRLFDVIHTENK-----LTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLV 110 Query: 175 KLYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVL-VKGEPNISY 351 K + +Q+ +A+ H + HRD+KPQNLL+N + QLK+ DFG A+ + S Sbjct: 111 KYFQWQLLQGVAFCHEN-RILHRDLKPQNLLIN-NRGQLKLGDFGLARAFGIPVNTFSSE 168 Query: 352 ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + + +YRAP+++ G+ Y T+IDIWS GC+LAE+ Sbjct: 169 VVTLWYRAPDVLMGSRNYCTSIDIWSCGCILAEM 202
>PCTK3_PONPY (Q5RD01) Serine/threonine-protein kinase PCTAIRE-3 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 3) Length = 472 Score = 91.7 bits (226), Expect = 8e-19 Identities = 54/154 (35%), Positives = 87/154 (56%), Gaps = 3/154 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +++ L H N+V+L H T L LV EY+ + + + H + M + VK+ Sbjct: 191 LLKNLKHANIVTL-HDLIHTDRS----LTLVFEYLDSDLKQYLDHCGNL---MSMHNVKI 242 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY--- 351 + +Q+ LAY H + HRD+KPQNLL+N +LK+ DFG A+ K P +Y Sbjct: 243 FMFQLLRGLAYCHHRK-ILHRDLKPQNLLINERG-ELKLADFGLARA--KSVPTKTYSNE 298 Query: 352 ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + + +YR P+++ G+TEY+T ID+W GC+ E+ Sbjct: 299 VVTLWYRPPDVLLGSTEYSTPIDMWGVGCIHYEM 332
>PCTK3_HUMAN (Q07002) Serine/threonine-protein kinase PCTAIRE-3 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 3) Length = 472 Score = 91.7 bits (226), Expect = 8e-19 Identities = 54/154 (35%), Positives = 87/154 (56%), Gaps = 3/154 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +++ L H N+V+L H T L LV EY+ + + + H + M + VK+ Sbjct: 191 LLKNLKHANIVTL-HDLIHTDRS----LTLVFEYLDSDLKQYLDHCGNL---MSMHNVKI 242 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY--- 351 + +Q+ LAY H + HRD+KPQNLL+N +LK+ DFG A+ K P +Y Sbjct: 243 FMFQLLRGLAYCHHRK-ILHRDLKPQNLLINERG-ELKLADFGLARA--KSVPTKTYSNE 298 Query: 352 ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + + +YR P+++ G+TEY+T ID+W GC+ E+ Sbjct: 299 VVTLWYRPPDVLLGSTEYSTPIDMWGVGCIHYEM 332
>CDK5_XENLA (P51166) Cell division protein kinase 5 (EC 2.7.11.22) (Neuronal| cyclin-dependent kinase 5) Length = 292 Score = 91.7 bits (226), Expect = 8e-19 Identities = 56/154 (36%), Positives = 87/154 (56%), Gaps = 3/154 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +++ L H N+V L S + L LV E+ + + + +++ N + VK Sbjct: 54 LLKELKHKNIVRLHDVLHSDKK-----LTLVFEFCDQDLKK---YFDSCNGDLDPEIVKS 105 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY--- 351 + YQ+ LA+ H V HRD+KPQNLL+N +LK+ DFG A+ G P Y Sbjct: 106 FMYQLLKGLAFCHSR-NVLHRDLKPQNLLIN-RNGELKLADFGLARAF--GIPVRCYSAE 161 Query: 352 ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + + +YR P+++FGA Y+T+ID+WSAGC+ AEL Sbjct: 162 VVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAEL 195
>CDKL3_RAT (Q9JM01) Cyclin-dependent kinase-like 3 (EC 2.7.11.22)| (Serine/threonine protein kinase NKIATRE) Length = 593 Score = 91.7 bits (226), Expect = 8e-19 Identities = 52/146 (35%), Positives = 84/146 (57%), Gaps = 1/146 (0%) Frame = +1 Query: 19 HPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKLYSYQIC 198 H N+V+L F + + ++LV E++ TV ++HY + L + Y +QI Sbjct: 59 HENLVNLIEVF-----RQKKKIHLVFEFIDHTVLDELQHYCHGLESKRL---RKYLFQIL 110 Query: 199 XALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVK-GEPNISYICSRYYRA 375 A+ Y+H + HRDIKP+N+LV+ + K+CDFG A+ L G+ Y+ +R+YRA Sbjct: 111 RAIEYLHNN-NIIHRDIKPENILVS-QSGITKLCDFGFARTLAAPGDVYTDYVATRWYRA 168 Query: 376 PELIFGATEYTTAIDIWSAGCVLAEL 453 PEL+ T Y +DIW+ GC++ E+ Sbjct: 169 PELVLKDTTYGKPVDIWALGCMIIEM 194
>CDK5_DROME (P48609) Cell division protein kinase 5 homolog (EC 2.7.11.22)| Length = 294 Score = 91.7 bits (226), Expect = 8e-19 Identities = 55/154 (35%), Positives = 90/154 (58%), Gaps = 3/154 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +++ L H N+V L S + L LV E+ + + + +++ +N + + + Sbjct: 54 LLKELKHKNIVRLIDVLHSDKK-----LTLVFEHCDQDLKK---YFDSLNGEIDMAVCRS 105 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY--- 351 + Q+ LA+ H + V HRD+KPQNLL+N + +LK+ DFG A+ G P Y Sbjct: 106 FMLQLLRGLAFCH-SHNVLHRDLKPQNLLINKNG-ELKLADFGLARAF--GIPVKCYSAE 161 Query: 352 ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + + +YR P+++FGA YTT+ID+WSAGC+LAEL Sbjct: 162 VVTLWYRPPDVLFGAKLYTTSIDMWSAGCILAEL 195
>CDKL3_MACFA (Q4R8T9) Cyclin-dependent kinase-like 3 (EC 2.7.11.22)| Length = 590 Score = 91.3 bits (225), Expect = 1e-18 Identities = 52/151 (34%), Positives = 86/151 (56%), Gaps = 1/151 (0%) Frame = +1 Query: 4 MRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKLY 183 ++ H N+V+L F + + ++LV E++ TV ++HY + L + Y Sbjct: 54 LKQFHHENLVNLIEVF-----RQKKKIHLVFEFIDHTVLDELQHYCHGLESKRL---RKY 105 Query: 184 SYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVK-GEPNISYICS 360 +QI A+ Y+H + HRDIKP+N+LV+ + K+CDFG A+ L G+ Y+ + Sbjct: 106 LFQILRAIDYLHSN-NIIHRDIKPENILVS-QSGITKLCDFGFARTLAAPGDIYTDYVAT 163 Query: 361 RYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 R+YRAPEL+ T Y +DIW+ GC++ E+ Sbjct: 164 RWYRAPELVLKDTSYGKPVDIWALGCMIIEM 194
>CDKL3_HUMAN (Q8IVW4) Cyclin-dependent kinase-like 3 (EC 2.7.11.22)| (Serine/threonine protein kinase NKIAMRE) Length = 592 Score = 91.3 bits (225), Expect = 1e-18 Identities = 52/151 (34%), Positives = 86/151 (56%), Gaps = 1/151 (0%) Frame = +1 Query: 4 MRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKLY 183 ++ H N+V+L F + + ++LV E++ TV ++HY + L + Y Sbjct: 54 LKQFHHENLVNLIEVF-----RQKKKIHLVFEFIDHTVLDELQHYCHGLESKRL---RKY 105 Query: 184 SYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVK-GEPNISYICS 360 +QI A+ Y+H + HRDIKP+N+LV+ + K+CDFG A+ L G+ Y+ + Sbjct: 106 LFQILRAIDYLHSN-NIIHRDIKPENILVS-QSGITKLCDFGFARTLAAPGDIYTDYVAT 163 Query: 361 RYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 R+YRAPEL+ T Y +DIW+ GC++ E+ Sbjct: 164 RWYRAPELVLKDTSYGKPVDIWALGCMIIEM 194
>MHK_ARATH (P43294) Serine/threonine-protein kinase MHK (EC 2.7.11.22)| Length = 443 Score = 91.3 bits (225), Expect = 1e-18 Identities = 55/152 (36%), Positives = 89/152 (58%), Gaps = 2/152 (1%) Frame = +1 Query: 4 MRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKLY 183 +R L+HP+++ LK E +ELF ++ E + + H K +R P ++ Sbjct: 62 LRKLNHPHIIKLKEI---VREHNELF------FIFECMDHNLYHIMKERER-PFSEGEIR 111 Query: 184 SY--QICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYIC 357 S+ Q+ LA++H+ G HRD+KP+NLLV + LKI DFG A+ + P Y+ Sbjct: 112 SFMSQMLQGLAHMHKN-GYFHRDLKPENLLVTNNI--LKIADFGLAREVASMPPYTEYVS 168 Query: 358 SRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 +R+YRAPE++ ++ YT A+D+W+ G +LAEL Sbjct: 169 TRWYRAPEVLLQSSLYTPAVDMWAVGAILAEL 200
>CDK3_HUMAN (Q00526) Cell division protein kinase 3 (EC 2.7.11.22)| Length = 305 Score = 90.9 bits (224), Expect = 1e-18 Identities = 54/154 (35%), Positives = 89/154 (57%), Gaps = 3/154 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +++ L HPN+V L + E L LV E++ + + + + + +PL +K Sbjct: 54 LLKELKHPNIVRLLDVVHN-----ERKLYLVFEFLSQDLKKYMD--STPGSELPLHLIKS 106 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY--- 351 Y +Q+ +++ H + V HRD+KPQNLL+N +K+ DFG A+ G P +Y Sbjct: 107 YLFQLLQGVSFCH-SHRVIHRDLKPQNLLIN-ELGAIKLADFGLARAF--GVPLRTYTHE 162 Query: 352 ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + + +YRAPE++ G+ YTTA+DIWS GC+ AE+ Sbjct: 163 VVTLWYRAPEILLGSKFYTTAVDIWSIGCIFAEM 196
>SLT2_YEAST (Q00772) Mitogen-activated protein kinase SLT2/MPK1 (EC 2.7.11.24)| (MAP kinase MPK1) Length = 484 Score = 90.9 bits (224), Expect = 1e-18 Identities = 55/128 (42%), Positives = 75/128 (58%), Gaps = 5/128 (3%) Frame = +1 Query: 82 LNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKLYSYQICXALAYIHRTVGVCHRDIKPQN 261 L L E + +H++I K Q + + + ++YQI L YIH + V HRD+KP N Sbjct: 104 LYLYEELMECDMHQII----KSGQPLTDAHYQSFTYQILCGLKYIH-SADVLHRDLKPGN 158 Query: 262 LLVNPHTHQLKICDFGSAKVLVKGEPNIS-----YICSRYYRAPELIFGATEYTTAIDIW 426 LLVN QLKICDFG A+ + S Y+ +R+YRAPE++ YT AID+W Sbjct: 159 LLVNADC-QLKICDFGLARGYSENPVENSQFLTEYVATRWYRAPEIMLSYQGYTKAIDVW 217 Query: 427 SAGCVLAE 450 SAGC+LAE Sbjct: 218 SAGCILAE 225
>CDK2_RAT (Q63699) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 90.9 bits (224), Expect = 1e-18 Identities = 55/154 (35%), Positives = 88/154 (57%), Gaps = 3/154 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +++ L+HPN+V L + + L LV E++ + + + + +PLI K Sbjct: 54 LLKELNHPNIVKLLDVIHTENK-----LYLVFEFLHQDLKKFMDASALTGLPLPLI--KS 106 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY--- 351 Y +Q+ LA+ H + V HRD+KPQNLL+N +K+ DFG A+ G P +Y Sbjct: 107 YLFQLLQGLAFCH-SHRVLHRDLKPQNLLINAEG-SIKLADFGLARAF--GVPVRTYTHE 162 Query: 352 ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + + +YRAPE++ G Y+TA+DIWS GC+ AE+ Sbjct: 163 VVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEM 196
>MKC1_CANAL (P43068) Mitogen-activated protein kinase MKC1 (EC 2.7.11.24) (MAP| kinase MKC1) Length = 501 Score = 90.5 bits (223), Expect = 2e-18 Identities = 54/137 (39%), Positives = 80/137 (58%), Gaps = 5/137 (3%) Frame = +1 Query: 58 TTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKLYSYQICXALAYIHRTVGVC 237 T E +E++L E + +H++IR ++ + + + + YQ+ L +IH + V Sbjct: 119 TGEFNEIYL--YEELMECDMHQIIRSGQPLSDQ----HYQSFIYQVLCGLNFIH-SADVL 171 Query: 238 HRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPN-----ISYICSRYYRAPELIFGATE 402 HRD+KP NLLVN +LKICDFG A+ + Y+ +R+YRAPE++ T Sbjct: 172 HRDLKPGNLLVNADC-ELKICDFGLARGFSENPDENAGFMTEYVATRWYRAPEIMLSFTN 230 Query: 403 YTTAIDIWSAGCVLAEL 453 YT AIDIWS GC+LAEL Sbjct: 231 YTKAIDIWSVGCILAEL 247
>ERKA_DROME (P40417) Mitogen-activated protein kinase ERK-A (EC 2.7.11.24)| (Extracellular-regulated kinase A) (Protein rolled) Length = 376 Score = 90.5 bits (223), Expect = 2e-18 Identities = 47/105 (44%), Positives = 66/105 (62%), Gaps = 4/105 (3%) Frame = +1 Query: 151 QRMPLIYVKLYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVK 330 QR+ ++ + YQI L YIH + V HRD+KP NLL+N T LKICDFG A++ Sbjct: 132 QRLSNDHICYFLYQILRGLKYIH-SANVLHRDLKPSNLLLNK-TCDLKICDFGLARIADP 189 Query: 331 GEPNIS----YICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + Y+ +R+YRAPE++ + YT +IDIWS GC+LAE+ Sbjct: 190 EHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEM 234
>CDK2_MOUSE (P97377) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 346 Score = 90.5 bits (223), Expect = 2e-18 Identities = 55/154 (35%), Positives = 88/154 (57%), Gaps = 3/154 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +++ L+HPN+V L + + L LV E++ + + + + +PLI K Sbjct: 54 LLKELNHPNIVKLLDVIHTENK-----LYLVFEFLHQDLKKFMDASALTGIPLPLI--KS 106 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY--- 351 Y +Q+ LA+ H + V HRD+KPQNLL+N +K+ DFG A+ G P +Y Sbjct: 107 YLFQLLQGLAFCH-SHRVLHRDLKPQNLLINAEG-SIKLADFGLARAF--GVPVRTYTHE 162 Query: 352 ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + + +YRAPE++ G Y+TA+DIWS GC+ AE+ Sbjct: 163 VVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEM 196
>CDK2_MESAU (P48963) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 90.5 bits (223), Expect = 2e-18 Identities = 55/156 (35%), Positives = 92/156 (58%), Gaps = 5/156 (3%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQ--RMPLIYV 174 +++ L+HPN+V L + +++L+L V E +H+ ++ + + +PL + Sbjct: 54 LLKELNHPNIVKLLDVIHT---ENKLYL------VFELLHQDLKKFMDASAVTGIPLPLI 104 Query: 175 KLYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY- 351 K Y +Q+ LA+ H + V HRD+KPQNLL+N +K+ DFG A+ G P +Y Sbjct: 105 KSYLFQLLQGLAFCH-SHRVLHRDLKPQNLLINAEG-SIKLADFGLARAF--GVPVRTYT 160 Query: 352 --ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + + +YRAPE++ G Y+TA+DIWS GC+ AE+ Sbjct: 161 HEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEM 196
>CDK2_CRIGR (O55076) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 90.5 bits (223), Expect = 2e-18 Identities = 55/154 (35%), Positives = 88/154 (57%), Gaps = 3/154 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +++ L+HPN+V L + + L LV E++ + + + + +PLI K Sbjct: 54 LLKELNHPNIVKLLDVIHTENK-----LYLVFEFLHQDLKKFMDASAVTGIPLPLI--KS 106 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY--- 351 Y +Q+ LA+ H + V HRD+KPQNLL+N +K+ DFG A+ G P +Y Sbjct: 107 YLFQLLQGLAFCH-SHRVLHRDLKPQNLLINAEG-SIKLADFGLARAF--GVPVRTYTHE 162 Query: 352 ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + + +YRAPE++ G Y+TA+DIWS GC+ AE+ Sbjct: 163 VVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEM 196
>PHO85_YARLI (Q6C7U8) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 294 Score = 90.5 bits (223), Expect = 2e-18 Identities = 55/154 (35%), Positives = 89/154 (57%), Gaps = 3/154 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +M+ L H N+V+L + + LNLV EY+ + + + + N + VK Sbjct: 56 LMKELKHENIVTLYDVIHTENK-----LNLVFEYMDKDLKKFM-DTNGNKGALETKQVKW 109 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY--- 351 + YQ+ + + H V HRD+KPQNLL+N QLK+ DFG A+ G P ++ Sbjct: 110 FMYQLLRGILFCHDN-RVLHRDLKPQNLLINAKG-QLKLADFGLARAF--GIPVNTFSNE 165 Query: 352 ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + + +YRAP+++ G+ Y+T+IDIWSAGC++AE+ Sbjct: 166 VVTLWYRAPDVLLGSRTYSTSIDIWSAGCIMAEM 199
>CDC21_ORYSA (P29618) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| Length = 294 Score = 90.5 bits (223), Expect = 2e-18 Identities = 54/154 (35%), Positives = 88/154 (57%), Gaps = 3/154 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +++ + H N+V L S E + LV EY+ + + + + + LI K Sbjct: 54 LLKEMHHGNIVRLHDVIHS-----EKRIYLVFEYLDLDLKKFMDSCPEFAKNPTLI--KS 106 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY--- 351 Y YQI +AY H + V HRD+KPQNLL++ T+ LK+ DFG A+ G P ++ Sbjct: 107 YLYQILRGVAYCH-SHRVLHRDLKPQNLLIDRRTNALKLADFGLARAF--GIPVRTFTHE 163 Query: 352 ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + + +YRAPE++ G+ +Y+T +D+WS GC+ AE+ Sbjct: 164 VVTLWYRAPEILLGSRQYSTPVDMWSVGCIFAEM 197
>KC47_ORYSA (P29620) CDC2+/CDC28-related protein kinase R2 (EC 2.7.11.22)| Length = 424 Score = 90.1 bits (222), Expect = 2e-18 Identities = 51/125 (40%), Positives = 76/125 (60%), Gaps = 1/125 (0%) Frame = +1 Query: 82 LNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKLYSYQICXALAYIHRTVGVCHRDIKPQN 261 L+LV E++ + VIR N + + K Y + LA+ H+ V HRD+KP N Sbjct: 91 LHLVFEFMETDLEAVIRDRNIV---LSPADTKSYIQMMLKGLAFCHKK-WVLHRDMKPNN 146 Query: 262 LLVNPHTHQLKICDFGSAKVLVKGEPNISY-ICSRYYRAPELIFGATEYTTAIDIWSAGC 438 LL+ QLK+ DFG A++ E N ++ + +R+YRAPEL+FG +Y +A+DIW+AGC Sbjct: 147 LLIGADG-QLKLADFGLARIFGSPERNFTHQVFARWYRAPELLFGTKQYGSAVDIWAAGC 205 Query: 439 VLAEL 453 + AEL Sbjct: 206 IFAEL 210
>CDK2_HUMAN (P24941) Cell division protein kinase 2 (EC 2.7.11.22) (p33 protein| kinase) Length = 298 Score = 90.1 bits (222), Expect = 2e-18 Identities = 55/154 (35%), Positives = 88/154 (57%), Gaps = 3/154 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +++ L+HPN+V L + + L LV E++ + + + + +PLI K Sbjct: 54 LLKELNHPNIVKLLDVIHTENK-----LYLVFEFLHQDLKKFMDASALTGIPLPLI--KS 106 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY--- 351 Y +Q+ LA+ H + V HRD+KPQNLL+N +K+ DFG A+ G P +Y Sbjct: 107 YLFQLLQGLAFCH-SHRVLHRDLKPQNLLINTEG-AIKLADFGLARAF--GVPVRTYTHE 162 Query: 352 ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + + +YRAPE++ G Y+TA+DIWS GC+ AE+ Sbjct: 163 VVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEM 196
>CDK2_BOVIN (Q5E9Y0) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 90.1 bits (222), Expect = 2e-18 Identities = 55/154 (35%), Positives = 88/154 (57%), Gaps = 3/154 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +++ L+HPN+V L + + L LV E++ + + + + +PLI K Sbjct: 54 LLKELNHPNIVKLLDVIHTENK-----LYLVFEFLHQDLKKFMDASALTGIPLPLI--KS 106 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY--- 351 Y +Q+ LA+ H + V HRD+KPQNLL+N +K+ DFG A+ G P +Y Sbjct: 107 YLFQLLQGLAFCH-SHRVLHRDLKPQNLLINADG-SIKLADFGLARAF--GVPVRTYTHE 162 Query: 352 ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + + +YRAPE++ G Y+TA+DIWS GC+ AE+ Sbjct: 163 VVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEM 196
>AL2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.11.22)| (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 7 protein) Length = 384 Score = 89.7 bits (221), Expect = 3e-18 Identities = 58/157 (36%), Positives = 90/157 (57%), Gaps = 6/157 (3%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIY--- 171 +++ L H N+V L H T E L +V E +H + Y M+Q ++ Sbjct: 101 LLKGLKHANIVLL-HDIIHTKE--------TLTFVFEYMHTDLAQY--MSQHPGGLHPHN 149 Query: 172 VKLYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY 351 V+L+ +Q+ LAYIH V HRD+KPQNLL++ H +LK+ DFG A+ K P+ +Y Sbjct: 150 VRLFMFQLLRGLAYIHHQ-HVLHRDLKPQNLLIS-HLGELKLADFGLARA--KSIPSQTY 205 Query: 352 ---ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + + +YR P+ + GATEY++ +DIW AGC+ E+ Sbjct: 206 SSEVVTLWYRPPDALLGATEYSSELDIWGAGCIFIEM 242
>CDK7_RAT (P51952) Cell division protein kinase 7 (EC 2.7.11.22) (EC| 2.7.11.23) (CDK-activating kinase) (CAK) (TFIIH basal transcription factor complex kinase subunit) (39 protein kinase) (P39 Mo15) (Fragment) Length = 329 Score = 89.7 bits (221), Expect = 3e-18 Identities = 52/154 (33%), Positives = 88/154 (57%), Gaps = 3/154 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +++ L HPN++ L F + ++LV +++ + +I+ + + + ++K Sbjct: 57 LLQELSHPNIIGLLDAFGHKSN-----ISLVFDFMETDLEVIIKDNSLV---LTPSHIKA 108 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY--- 351 Y L Y+H+ + HRD+KP NLL++ + LK+ DFG AK G PN +Y Sbjct: 109 YMLMTLQGLEYLHQH-WILHRDLKPNNLLLDENG-VLKLADFGLAKSF--GSPNWAYTHQ 164 Query: 352 ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + +R+YRAPEL+FGA Y +D+W+ GC+LAEL Sbjct: 165 VVTRWYRAPELLFGARMYGVGVDMWAVGCILAEL 198
>CDK7_MOUSE (Q03147) Cell division protein kinase 7 (EC 2.7.11.22) (EC| 2.7.11.23) (CDK-activating kinase) (CAK) (TFIIH basal transcription factor complex kinase subunit) (39 kDa protein kinase) (P39 Mo15) (Protein-tyrosine kinase MPK-7) (CR4 protein kinas Length = 346 Score = 89.7 bits (221), Expect = 3e-18 Identities = 52/154 (33%), Positives = 88/154 (57%), Gaps = 3/154 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +++ L HPN++ L F + ++LV +++ + +I+ + + + ++K Sbjct: 65 LLQELSHPNIIGLLDAFGHKSN-----ISLVFDFMETDLEVIIKDNSLV---LTPSHIKA 116 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY--- 351 Y L Y+H+ + HRD+KP NLL++ + LK+ DFG AK G PN +Y Sbjct: 117 YMLMTLQGLEYLHQH-WILHRDLKPNNLLLDENG-VLKLADFGLAKSF--GSPNRAYTHQ 172 Query: 352 ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + +R+YRAPEL+FGA Y +D+W+ GC+LAEL Sbjct: 173 VVTRWYRAPELLFGARMYGVGVDMWAVGCILAEL 206
>CDK7_HUMAN (P50613) Cell division protein kinase 7 (EC 2.7.11.22) (EC| 2.7.11.23) (CDK-activating kinase) (CAK) (TFIIH basal transcription factor complex kinase subunit) (39 kDa protein kinase) (P39 Mo15) (STK1) (CAK1) Length = 346 Score = 89.7 bits (221), Expect = 3e-18 Identities = 52/154 (33%), Positives = 88/154 (57%), Gaps = 3/154 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +++ L HPN++ L F + ++LV +++ + +I+ + + + ++K Sbjct: 65 LLQELSHPNIIGLLDAFGHKSN-----ISLVFDFMETDLEVIIKDNSLV---LTPSHIKA 116 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY--- 351 Y L Y+H+ + HRD+KP NLL++ + LK+ DFG AK G PN +Y Sbjct: 117 YMLMTLQGLEYLHQH-WILHRDLKPNNLLLDENG-VLKLADFGLAKSF--GSPNRAYTHQ 172 Query: 352 ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + +R+YRAPEL+FGA Y +D+W+ GC+LAEL Sbjct: 173 VVTRWYRAPELLFGARMYGVGVDMWAVGCILAEL 206
>PCTK1_MOUSE (Q04735) Serine/threonine-protein kinase PCTAIRE-1 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 1) (CRK5) Length = 496 Score = 89.7 bits (221), Expect = 3e-18 Identities = 55/154 (35%), Positives = 89/154 (57%), Gaps = 3/154 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +++ L H N+V+L TEK L LV EY+ + + + + + + + VKL Sbjct: 214 LLKDLKHANIVTLHDIIH--TEKS---LTLVFEYLDKDLKQYLDDCGNV---INMHNVKL 265 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY--- 351 + +Q+ LAY HR V HRD+KPQNLL+N +LK+ DFG A+ K P +Y Sbjct: 266 FLFQLLRGLAYCHRQK-VLHRDLKPQNLLINERG-ELKLADFGLARA--KSIPTKTYSNE 321 Query: 352 ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + + +YR P+++ G+T+Y+T ID+W GC+ E+ Sbjct: 322 VVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEM 355
>PCTK1_HUMAN (Q00536) Serine/threonine-protein kinase PCTAIRE-1 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 1) Length = 496 Score = 89.7 bits (221), Expect = 3e-18 Identities = 55/154 (35%), Positives = 89/154 (57%), Gaps = 3/154 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +++ L H N+V+L TEK L LV EY+ + + + + + + + VKL Sbjct: 214 LLKDLKHANIVTLHDIIH--TEKS---LTLVFEYLDKDLKQYLDDCGNI---INMHNVKL 265 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY--- 351 + +Q+ LAY HR V HRD+KPQNLL+N +LK+ DFG A+ K P +Y Sbjct: 266 FLFQLLRGLAYCHRQK-VLHRDLKPQNLLINERG-ELKLADFGLARA--KSIPTKTYSNE 321 Query: 352 ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + + +YR P+++ G+T+Y+T ID+W GC+ E+ Sbjct: 322 VVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEM 355
>PFTK1_MOUSE (O35495) Serine/threonine-protein kinase PFTAIRE-1 (EC 2.7.11.22)| Length = 469 Score = 89.4 bits (220), Expect = 4e-18 Identities = 58/157 (36%), Positives = 91/157 (57%), Gaps = 6/157 (3%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIY--- 171 +++ L H N+V L H T E L LV EYV H + Y M Q ++ Sbjct: 184 LLKGLKHANIVLL-HDIIHTKET----LTLVFEYV----HTDLCQY--MEQHPGGLHPDN 232 Query: 172 VKLYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY 351 VKL+ +Q+ L+YIH+ + HRD+KPQNLL++ T +LK+ DFG A+ K P+ +Y Sbjct: 233 VKLFLFQLLRGLSYIHQRY-ILHRDLKPQNLLISD-TGELKLADFGLARA--KSVPSHTY 288 Query: 352 ---ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + + +YR P+++ G+TEY+T +D+W GC+ E+ Sbjct: 289 SNEVVTLWYRPPDVLLGSTEYSTCLDMWGVGCIFVEM 325
>PFTK1_HUMAN (O94921) Serine/threonine-protein kinase PFTAIRE-1 (EC 2.7.11.22)| Length = 469 Score = 89.4 bits (220), Expect = 4e-18 Identities = 55/154 (35%), Positives = 90/154 (58%), Gaps = 3/154 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +++ L H N+V L H T E L LV EYV + ++ +K + VKL Sbjct: 184 LLKGLKHANIVLL-HDIIHTKET----LTLVFEYVHTDL---CQYMDKHPGGLHPDNVKL 235 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY--- 351 + +Q+ L+YIH+ + HRD+KPQNLL++ T +LK+ DFG A+ K P+ +Y Sbjct: 236 FLFQLLRGLSYIHQRY-ILHRDLKPQNLLISD-TGELKLADFGLARA--KSVPSHTYSNE 291 Query: 352 ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + + +YR P+++ G+TEY+T +D+W GC+ E+ Sbjct: 292 VVTLWYRPPDVLLGSTEYSTCLDMWGVGCIFVEM 325
>PHO85_ASHGO (Q751E8) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 303 Score = 89.4 bits (220), Expect = 4e-18 Identities = 53/154 (34%), Positives = 88/154 (57%), Gaps = 3/154 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVI--RHYNKMNQRMPLIYV 174 +M+ L H N+V L + + L LV E++ + + + R +M + + L V Sbjct: 58 LMKELKHENIVRLYDVIHTENK-----LTLVFEFMDNDLKKFMDSRLDREMPRGLELSLV 112 Query: 175 KLYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVL-VKGEPNISY 351 K + +Q+ +A+ H + HRD+KPQNLL+N + QLK+ DFG A+ + S Sbjct: 113 KYFQWQLLQGVAFCHEN-RILHRDLKPQNLLIN-NKGQLKLGDFGLARAFGIPVNTFSSE 170 Query: 352 ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + + +YRAP+++ G+ Y T+IDIWS GC+LAE+ Sbjct: 171 VVTLWYRAPDVLMGSRTYCTSIDIWSCGCILAEM 204
>CDC2H_THEPA (Q27032) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 298 Score = 89.4 bits (220), Expect = 4e-18 Identities = 51/152 (33%), Positives = 88/152 (57%), Gaps = 1/152 (0%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +++ L HPN+V L+ S E L LV EY+ + + +++ + + + K Sbjct: 53 LLKELHHPNIVWLRDVIHS-----EKCLTLVFEYLDQDLKKLL---DACDGGLEPTTAKS 104 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY-IC 357 + YQI ++Y H + HRD+KPQNLL+N LK+ DFG A+ + ++ + Sbjct: 105 FLYQILRGISYCHDH-RILHRDLKPQNLLIN-REGVLKLADFGLARAFAIPVRSYTHEVV 162 Query: 358 SRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + +YRAP+++ G+ +Y+TA+DIWS GC+ AE+ Sbjct: 163 TLWYRAPDVLMGSKKYSTAVDIWSVGCIFAEM 194
>CDC2H_THEAN (Q26671) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 298 Score = 89.4 bits (220), Expect = 4e-18 Identities = 51/152 (33%), Positives = 88/152 (57%), Gaps = 1/152 (0%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +++ L HPN+V L+ S E L LV EY+ + + +++ + + + K Sbjct: 53 LLKELHHPNIVWLRDVIHS-----EKCLTLVFEYLDQDLKKLL---DACDGGLEPTTAKS 104 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY-IC 357 + YQI ++Y H + HRD+KPQNLL+N LK+ DFG A+ + ++ + Sbjct: 105 FLYQILRGISYCHDH-RILHRDLKPQNLLIN-REGVLKLADFGLARAFAIPVRSYTHEVV 162 Query: 358 SRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + +YRAP+++ G+ +Y+TA+DIWS GC+ AE+ Sbjct: 163 TLWYRAPDVLMGSKKYSTAVDIWSVGCIFAEM 194
>CDK5_BOVIN (Q02399) Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein| kinase II catalytic subunit) (TPKII catalytic subunit) (Proline-directed protein kinase 33 kDa subunit) (PDPK) Length = 292 Score = 89.0 bits (219), Expect = 5e-18 Identities = 54/154 (35%), Positives = 87/154 (56%), Gaps = 3/154 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +++ L H N+V L S + L LV E+ + + + +++ N + VK Sbjct: 54 LLKELKHKNIVRLHDVLHSDKK-----LTLVFEFCDQDLKK---YFDSCNGDLDPEIVKS 105 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY--- 351 + +Q+ L + H V HRD+KPQNLL+N +LK+ DFG A+ G P Y Sbjct: 106 FLFQLLKGLGFCHSR-NVLHRDLKPQNLLIN-RNGELKLADFGLARAF--GIPVRCYSAE 161 Query: 352 ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + + +YR+P+++FGA Y+T+ID+WSAGC+ AEL Sbjct: 162 VVTLWYRSPDVLFGAKLYSTSIDMWSAGCIFAEL 195
>MK14C_DROME (P83100) Putative mitogen-activated protein kinase 14C (EC| 2.7.11.24) (MAP kinase p38c) Length = 356 Score = 89.0 bits (219), Expect = 5e-18 Identities = 54/153 (35%), Positives = 89/153 (58%), Gaps = 2/153 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELF--LNLVLEYVPETVHRVIRHYNKMNQRMPLIYV 174 +++ ++H NV+SL + F F + LV + +HR R ++RM + Sbjct: 70 LLKHMNHRNVISLLNVFHPPAHNMMEFQQVYLVTHLMDADLHRYSR-----SKRMSDQEI 124 Query: 175 KLYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYI 354 ++ YQI L YIH + GV HRD+KP N+ VN ++ +++I DFG +++ + ++ Sbjct: 125 RIILYQILRGLKYIH-SAGVVHRDLKPCNIAVNGNS-EVRILDFGLSRMCA--DKMTDHV 180 Query: 355 CSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + +Y APE+IF +YT AID+WS GC+LAEL Sbjct: 181 GTMWYLAPEIIFLRGQYTKAIDVWSVGCILAEL 213
>PHO85_YEAST (P17157) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 305 Score = 89.0 bits (219), Expect = 5e-18 Identities = 53/154 (34%), Positives = 86/154 (55%), Gaps = 3/154 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVI--RHYNKMNQRMPLIYV 174 +M+ L H N+V L + + L LV E++ + + + R + + L V Sbjct: 56 LMKELKHENIVRLYDVIHTENK-----LTLVFEFMDNDLKKYMDSRTVGNTPRGLELNLV 110 Query: 175 KLYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVL-VKGEPNISY 351 K + +Q+ LA+ H + HRD+KPQNLL+N QLK+ DFG A+ + S Sbjct: 111 KYFQWQLLQGLAFCHENK-ILHRDLKPQNLLINKRG-QLKLGDFGLARAFGIPVNTFSSE 168 Query: 352 ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + + +YRAP+++ G+ Y+T+IDIWS GC+LAE+ Sbjct: 169 VVTLWYRAPDVLMGSRTYSTSIDIWSCGCILAEM 202
>CDC2_VIGAC (Q41639) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) Length = 294 Score = 88.6 bits (218), Expect = 7e-18 Identities = 54/158 (34%), Positives = 88/158 (55%), Gaps = 7/158 (4%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLI---- 168 +++ + H N+V L+ S E L LV EY+ + + M+ + Sbjct: 54 LLKEMQHRNIVRLQDVVHS-----EKRLYLVFEYLDLDLKK------HMDSSPEFVKDPR 102 Query: 169 YVKLYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNIS 348 VK++ YQI +AY H + V HRD+KPQNLL++ T+ LK+ DFG A+ G P + Sbjct: 103 QVKMFLYQILCGIAYCH-SHRVLHRDLKPQNLLIDRRTNSLKLADFGLARAF--GIPVRT 159 Query: 349 Y---ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + + + +YRAPE++ G+ Y+T +D+WS GC+ AE+ Sbjct: 160 FTHEVVTLWYRAPEILLGSRHYSTPVDVWSVGCIFAEM 197
>CDC22_ORYSA (P29619) Cell division control protein 2 homolog 2 (EC 2.7.11.22)| Length = 292 Score = 88.6 bits (218), Expect = 7e-18 Identities = 53/154 (34%), Positives = 85/154 (55%), Gaps = 3/154 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +++ + H N+V L+ E + LV EY+ + + H + VK Sbjct: 54 LLKEMQHRNIVRLQDVVHK-----EKCIYLVFEYLDLDLKK---HMDSSPDFKNHRIVKS 105 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY--- 351 + YQI +AY H + V HRD+KPQNLL++ T+ LK+ DFG A+ G P ++ Sbjct: 106 FLYQILRGIAYCH-SHRVLHRDLKPQNLLIDRRTNSLKLADFGLARAF--GIPVRTFTHE 162 Query: 352 ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + + +YRAPE++ GA Y+T +D+WS GC+ AE+ Sbjct: 163 VVTLWYRAPEILLGARHYSTPVDMWSVGCIFAEM 196
>CDC2B_ARATH (P25859) Cell division control protein 2 homolog B (EC 2.7.11.22)| (EC 2.7.11.23) Length = 309 Score = 88.2 bits (217), Expect = 9e-18 Identities = 47/127 (37%), Positives = 73/127 (57%), Gaps = 3/127 (2%) Frame = +1 Query: 82 LNLVLEYVPETVHRVIRHYNKMNQRMPL--IYVKLYSYQICXALAYIHRTVGVCHRDIKP 255 L LV EY+ + + I Y K PL ++ +Q+C +A+ H + GV HRD+KP Sbjct: 87 LYLVFEYLDTDLKKFIDSYRKGPNPKPLEPFLIQKLMFQLCKGVAHCH-SHGVLHRDLKP 145 Query: 256 QNLLVNPHTHQLKICDFGSAKVLVKGEPNISY-ICSRYYRAPELIFGATEYTTAIDIWSA 432 QNLL+ LKI D G + + ++ I + +YRAPE++ G+T Y+T +D+WS Sbjct: 146 QNLLLVKDKELLKIADLGLGRAFTVPLKSYTHEIVTLWYRAPEVLLGSTHYSTGVDMWSV 205 Query: 433 GCVLAEL 453 GC+ AE+ Sbjct: 206 GCIFAEM 212
>CDK7_XENLA (P20911) Cell division protein kinase 7 (EC 2.7.11.22) (EC| 2.7.11.23) (40 kDa protein kinase) (P40 MO15) (CDC2/CDK2,4-activating kinase) Length = 352 Score = 88.2 bits (217), Expect = 9e-18 Identities = 51/154 (33%), Positives = 87/154 (56%), Gaps = 3/154 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +++ L HPN++ L F + ++LV +++ + +I+ + + + ++K Sbjct: 71 LLQELSHPNIIGLLDAFGHKSN-----ISLVFDFMETDLEVIIKDTSLV---LTPAHIKS 122 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY--- 351 Y L Y+H + + HRD+KP NLL++ + LK+ DFG AK G PN Y Sbjct: 123 YMLMTLQGLEYLHH-LWILHRDLKPNNLLLDENG-VLKLADFGLAKSF--GSPNRIYTHQ 178 Query: 352 ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + +R+YR+PEL+FGA Y +D+W+ GC+LAEL Sbjct: 179 VVTRWYRSPELLFGARMYGVGVDMWAVGCILAEL 212
>MK15_HUMAN (Q8TD08) Mitogen-activated protein kinase 15 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 8) Length = 544 Score = 88.2 bits (217), Expect = 9e-18 Identities = 49/152 (32%), Positives = 86/152 (56%), Gaps = 6/152 (3%) Frame = +1 Query: 16 DHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKLYSYQI 195 DHPN++SL + ++D + LV E++ ++ VIR + ++V+ YQ+ Sbjct: 69 DHPNIISLLDVIRAENDRD---IYLVFEFMDTDLNAVIRKGGLLQD----VHVRSIFYQL 121 Query: 196 CXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVL------VKGEPNISYIC 357 A ++H + V HRD KP N+L++ + +K+CDFG A+ L + + Y+ Sbjct: 122 LRATRFLH-SGHVVHRDQKPSNVLLDANC-TVKLCDFGLARSLGDLPEGPEDQAVTEYVA 179 Query: 358 SRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 +R+YRAPE++ + YT +D+WS GC+L E+ Sbjct: 180 TRWYRAPEVLLSSHRYTLGVDMWSLGCILGEM 211
>MK04_HUMAN (P31152) Mitogen-activated protein kinase 4 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 4) (ERK-4) (MAP kinase isoform p63) (p63-MAPK) Length = 557 Score = 88.2 bits (217), Expect = 9e-18 Identities = 53/161 (32%), Positives = 87/161 (54%), Gaps = 10/161 (6%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFF--STTEKDELF----LNLVLEYVPETVHRVIRHYNKMNQRMP 162 ++R LDH N+V + T + ELF +V EY+ + R++ + Sbjct: 68 IIRRLDHDNIVKVYEVLGPKGTDLQGELFKFSVAYIVQEYMETDLARLLEQGTLAEE--- 124 Query: 163 LIYVKLYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPN 342 + KL+ YQ+ L YIH + V HRD+KP N+ ++ LKI DFG A+++ + + Sbjct: 125 --HAKLFMYQLLRGLKYIH-SANVLHRDLKPANIFISTEDLVLKIGDFGLARIVDQHYSH 181 Query: 343 ISYIC----SRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 Y+ +++YR+P L+ YT AID+W+AGC+LAE+ Sbjct: 182 KGYLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCILAEM 222
>MK12_MOUSE (O08911) Mitogen-activated protein kinase 12 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 6) (ERK-6) (Stress-activated protein kinase 3) (Mitogen-activated protein kinase p38 gamma) (MAP kinase p38 gamma) Length = 367 Score = 88.2 bits (217), Expect = 9e-18 Identities = 52/152 (34%), Positives = 80/152 (52%), Gaps = 1/152 (0%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELF-LNLVLEYVPETVHRVIRHYNKMNQRMPLIYVK 177 +++ + H NV+ L F D+ LV+ ++ + ++++H R+ + Sbjct: 77 LLKHMRHENVIGLLDVFTPDESLDDFTDFYLVMPFMGTDLGKLMKHETLSEDRIQFLV-- 134 Query: 178 LYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYIC 357 YQ+ L YIH GV HRD+KP NL VN +LKI DFG A+ Y+ Sbjct: 135 ---YQMLKGLKYIH-AAGVIHRDLKPGNLAVNEDC-ELKILDFGLARQA--DSEMTGYVV 187 Query: 358 SRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 +R+YRAPE+I YT +DIWS GC++AE+ Sbjct: 188 TRWYRAPEVILNWMRYTQTVDIWSVGCIMAEM 219
>CDK5_MOUSE (P49615) Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein| kinase II catalytic subunit) (TPKII catalytic subunit) (Serine/threonine-protein kinase PSSALRE) (CRK6) Length = 292 Score = 88.2 bits (217), Expect = 9e-18 Identities = 54/154 (35%), Positives = 86/154 (55%), Gaps = 3/154 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +++ L H N+V L S + L LV E+ + + + +++ N + VK Sbjct: 54 LLKELKHKNIVRLHDVLHSDKK-----LTLVFEFCDQDLKK---YFDSCNGDLDPEIVKS 105 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY--- 351 + +Q+ L + H V HRD+KPQNLL+N +LK+ DFG A+ G P Y Sbjct: 106 FLFQLLKGLGFCHSR-NVLHRDLKPQNLLIN-RNGELKLADFGLARAF--GIPVRCYSAE 161 Query: 352 ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + + +YR P+++FGA Y+T+ID+WSAGC+ AEL Sbjct: 162 VVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAEL 195
>CDK5_HUMAN (Q00535) Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein| kinase II catalytic subunit) (TPKII catalytic subunit) (Serine/threonine-protein kinase PSSALRE) Length = 292 Score = 88.2 bits (217), Expect = 9e-18 Identities = 54/154 (35%), Positives = 86/154 (55%), Gaps = 3/154 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +++ L H N+V L S + L LV E+ + + + +++ N + VK Sbjct: 54 LLKELKHKNIVRLHDVLHSDKK-----LTLVFEFCDQDLKK---YFDSCNGDLDPEIVKS 105 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY--- 351 + +Q+ L + H V HRD+KPQNLL+N +LK+ DFG A+ G P Y Sbjct: 106 FLFQLLKGLGFCHSR-NVLHRDLKPQNLLIN-RNGELKLADFGLARAF--GIPVRCYSAE 161 Query: 352 ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + + +YR P+++FGA Y+T+ID+WSAGC+ AEL Sbjct: 162 VVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAEL 195
>CDK2_XENLA (P23437) Cell division protein kinase 2 (EC 2.7.11.22) (CDC2| homolog Eg1 protein kinase) Length = 297 Score = 88.2 bits (217), Expect = 9e-18 Identities = 54/154 (35%), Positives = 88/154 (57%), Gaps = 3/154 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +++ L+HPN+V L + + L LV E++ + + + + N + L VK Sbjct: 54 LLKELNHPNIVKLLDVIHTENK-----LYLVFEFLNQDLKKFMDGSNISG--ISLALVKS 106 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY--- 351 Y +Q+ LA+ H + V HRD+KPQNLL+N +K+ DFG A+ G P ++ Sbjct: 107 YLFQLLQGLAFCH-SHRVLHRDLKPQNLLINSDG-AIKLADFGLARAF--GVPVRTFTHE 162 Query: 352 ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + + +YRAPE++ G Y+TA+DIWS GC+ AE+ Sbjct: 163 VVTLWYRAPEILLGCKFYSTAVDIWSLGCIFAEM 196
>PHO85_DEBHA (Q6BRY2) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 330 Score = 87.8 bits (216), Expect = 1e-17 Identities = 52/154 (33%), Positives = 89/154 (57%), Gaps = 3/154 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +M+ LDH N+V+L + + L LV E++ + + + + + + L VK Sbjct: 57 LMKELDHENIVTLYDVIHTENK-----LTLVFEFMDKDLKKYMEAHGNQGA-LDLKIVKS 110 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY--- 351 + +Q+ + + H V HRD+KPQNLL+N + +LK+ DFG A+ G P ++ Sbjct: 111 FIFQLLKGIMFCHDN-RVLHRDLKPQNLLIN-NKGELKLGDFGLARAF--GIPFNTFSNE 166 Query: 352 ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + + +YRAP+++ G+ YT +IDIWSAGC+ AE+ Sbjct: 167 VVTLWYRAPDVLLGSRAYTASIDIWSAGCIFAEM 200
>MK12_RAT (Q63538) Mitogen-activated protein kinase 12 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 6) (ERK-6) (Stress-activated protein kinase 3) (Mitogen-activated protein kinase p38 gamma) (MAP kinase p38 gamma) Length = 367 Score = 87.8 bits (216), Expect = 1e-17 Identities = 52/152 (34%), Positives = 80/152 (52%), Gaps = 1/152 (0%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELF-LNLVLEYVPETVHRVIRHYNKMNQRMPLIYVK 177 +++ + H NV+ L F D+ LV+ ++ + ++++H R+ + Sbjct: 77 LLKHMRHENVIGLLDVFTPDETLDDFTDFYLVMPFMGTDLGKLMKHETLSEDRIQFLV-- 134 Query: 178 LYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYIC 357 YQ+ L YIH GV HRD+KP NL VN +LKI DFG A+ Y+ Sbjct: 135 ---YQMLKGLKYIH-AAGVIHRDLKPGNLAVNEDC-ELKILDFGLARQA--DSEMTGYVV 187 Query: 358 SRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 +R+YRAPE+I YT +DIWS GC++AE+ Sbjct: 188 TRWYRAPEVILNWMRYTQTVDIWSVGCIMAEM 219
>CDC2H_DICDI (P34117) CDC2-like serine/threonine-protein kinase CRP (EC| 2.7.11.22) (EC 2.7.11.23) Length = 292 Score = 87.8 bits (216), Expect = 1e-17 Identities = 55/154 (35%), Positives = 89/154 (57%), Gaps = 3/154 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +++ L HPN+V L H T K L LV EY+ + + + + ++ + +K Sbjct: 54 LLKELKHPNIVRL-HDVIHTERK----LTLVFEYLDQDLKKYL---DECGGEISKPTIKS 105 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY--- 351 + YQ+ +A+ H V HRD+KPQNLL+N +LK+ DFG A+ G P +Y Sbjct: 106 FMYQLLKGVAFCHDH-RVLHRDLKPQNLLIN-RKGELKLADFGLARAF--GIPVRTYSHE 161 Query: 352 ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + + +YRAP+++ G+ +Y+T IDIWSA C+ AE+ Sbjct: 162 VVTLWYRAPDVLMGSRKYSTPIDIWSALCIFAEM 195
>CDC2_VIGUN (P52389) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) Length = 294 Score = 87.8 bits (216), Expect = 1e-17 Identities = 54/158 (34%), Positives = 88/158 (55%), Gaps = 7/158 (4%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLI---- 168 +++ + H N+V L+ S E L LV EY+ + + M+ + Sbjct: 54 LLKEMQHRNIVRLQDVVHS-----EKRLYLVFEYLDLDLKK------HMDSSPEFVKDPR 102 Query: 169 YVKLYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNIS 348 VK++ YQI +AY H + V HRD+KPQNLL++ T+ LK+ DFG A+ G P + Sbjct: 103 QVKMFLYQILCGIAYCH-SHRVLHRDLKPQNLLIDRRTNSLKLADFGLARAF--GIPVRT 159 Query: 349 Y---ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + + + +YRAPE++ G+ Y+T +D+WS GC+ AE+ Sbjct: 160 FTHEVVTLWYRAPEILLGSRHYSTPVDVWSVGCLFAEM 197
>CDC2_CHERU (P93101) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) Length = 294 Score = 87.4 bits (215), Expect = 1e-17 Identities = 53/154 (34%), Positives = 87/154 (56%), Gaps = 3/154 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +++ + H N+V L+ S E L LV EY+ + + + + +I K Sbjct: 54 LLKEMQHGNIVRLQDVVHS-----EKRLYLVFEYLDLDLKKHMDSCPDFAKDPRMI--KR 106 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY--- 351 + YQI +AY H + V HRD+KPQNLL++ T+ LK+ DFG A+ G P ++ Sbjct: 107 FLYQILRGIAYCH-SHRVLHRDLKPQNLLIDRQTNALKLADFGLARAF--GIPVRTFTHE 163 Query: 352 ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + + +YRAPE++ G+ Y+T +D+WS GC+ AE+ Sbjct: 164 VVTLWYRAPEILLGSRHYSTPVDVWSVGCIFAEM 197
>PHO85_CANGA (Q6FKD4) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 302 Score = 87.4 bits (215), Expect = 1e-17 Identities = 52/154 (33%), Positives = 85/154 (55%), Gaps = 3/154 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVI--RHYNKMNQRMPLIYV 174 +M+ L H N+V L + + L LV EY+ + + + R + + + V Sbjct: 55 LMKELKHDNIVRLYDVIHTENK-----LTLVFEYMDNDLKKYMDSRTVGNAPRGLEMNLV 109 Query: 175 KLYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVL-VKGEPNISY 351 K + +Q+ LA+ H + HRD+KPQNLL+ QLK+ DFG A+ + S Sbjct: 110 KYFQWQLLEGLAFCHENK-ILHRDLKPQNLLITKRG-QLKLGDFGLARAFGIPVNTFSSE 167 Query: 352 ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + + +YRAP+++ G+ Y+T+IDIWS GC+LAE+ Sbjct: 168 VVTLWYRAPDVLMGSRTYSTSIDIWSCGCILAEM 201
>MK14B_DROME (O61443) Mitogen-activated protein kinase 14B (EC 2.7.11.24) (MAP| kinase p38b) (D-p38b) Length = 365 Score = 87.4 bits (215), Expect = 1e-17 Identities = 54/156 (34%), Positives = 84/156 (53%), Gaps = 5/156 (3%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELF----LNLVLEYVPETVHRVIRHYNKMNQRMPLI 168 +++ +DH NV+ L F D L + +V + ++ +IR Q++ Sbjct: 74 LLKHMDHENVIGLLDVFHPGQPADSLDQFQQVYMVTHLMDADLNNIIR-----TQKLSDD 128 Query: 169 YVKLYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNIS 348 +V+ YQI L YIH + GV HRD+KP N+ VN +L+I DFG A+ E ++ Sbjct: 129 HVQFLVYQILRGLKYIH-SAGVIHRDLKPSNIAVNEDC-ELRILDFGLAR---PAESEMT 183 Query: 349 -YICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 Y+ +R+YRAPE++ Y DIWS GC++AEL Sbjct: 184 GYVATRWYRAPEIMLNWMHYNQTADIWSVGCIMAEL 219
>CDC22_MEDSA (Q05006) Cell division control protein 2 homolog 2 (EC 2.7.11.22)| Length = 294 Score = 87.0 bits (214), Expect = 2e-17 Identities = 52/156 (33%), Positives = 90/156 (57%), Gaps = 5/156 (3%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKM--NQRMPLIYV 174 +++ + H N+V L+ S E L LV EY+ + + + + +QR + Sbjct: 54 LLKEMQHRNIVRLQDVVHS-----EKRLYLVFEYLDLDLKKFMDSSPEFAKDQRQ----I 104 Query: 175 KLYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY- 351 K++ YQI +AY H + V HRD+KPQNLL++ ++ +K+ DFG A+ G P ++ Sbjct: 105 KMFLYQILCGIAYCH-SHRVLHRDLKPQNLLIDRSSNAVKLADFGLARAF--GIPVRTFT 161 Query: 352 --ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + + +YRAPE++ G+ Y+T +D+WS GC+ AE+ Sbjct: 162 HEVVTLWYRAPEILLGSRHYSTPVDVWSVGCIFAEM 197
>MK14_XENLA (P47812) Mitogen-activated protein kinase 14 (EC 2.7.11.24)| (Mitogen-activated Mitogen-activated protein kinase 2) (MAP kinase 2) (MPK2) Length = 361 Score = 87.0 bits (214), Expect = 2e-17 Identities = 52/152 (34%), Positives = 82/152 (53%), Gaps = 1/152 (0%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELF-LNLVLEYVPETVHRVIRHYNKMNQRMPLIYVK 177 +++ + H NV+ L F +E + LV + ++ +++ Q++ +V+ Sbjct: 75 LLKHMKHENVIGLLDVFSPAKSFEEFNDVYLVTHLMGADLNNIVKC-----QKLTDDHVQ 129 Query: 178 LYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYIC 357 YQI L YIH + G+ HRD+KP NL VN +LKI DFG A+ E Y+ Sbjct: 130 FLIYQILRGLKYIH-SAGIIHRDLKPSNLAVNEDC-ELKILDFGLARHT--DEEMTGYVA 185 Query: 358 SRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 +R+YRAPE++ Y +DIWS GC++AEL Sbjct: 186 TRWYRAPEIMLNWMHYNQTVDIWSVGCIMAEL 217
>MK06_RAT (P27704) Mitogen-activated protein kinase 6 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 3) (ERK-3) (p55-MAPK) Length = 720 Score = 87.0 bits (214), Expect = 2e-17 Identities = 56/171 (32%), Positives = 92/171 (53%), Gaps = 20/171 (11%) Frame = +1 Query: 1 MMRLLDHPNVVS-----------LKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKM 147 ++R LDH N+V L S TE + +++ V EY+ + V+ Sbjct: 68 IIRRLDHDNIVKVFEILGPSGSQLTDDVGSLTELNSVYI--VQEYMETDLANVL------ 119 Query: 148 NQRMPLI--YVKLYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKV 321 ++ PL+ + +L+ YQ+ L YIH + V HRD+KP NL +N LKI DFG A++ Sbjct: 120 -EQGPLLEEHARLFMYQLLRGLKYIH-SANVLHRDLKPANLFINTEDLVLKIGDFGLARI 177 Query: 322 LVKGEPNISY-------ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + +P+ S+ + +++YR+P L+ YT AID+W+AGC+ AE+ Sbjct: 178 M---DPHYSHKGHLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEM 225
>MK06_MOUSE (Q61532) Mitogen-activated protein kinase 6 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 3) (ERK-3) Length = 720 Score = 87.0 bits (214), Expect = 2e-17 Identities = 56/171 (32%), Positives = 92/171 (53%), Gaps = 20/171 (11%) Frame = +1 Query: 1 MMRLLDHPNVVS-----------LKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKM 147 ++R LDH N+V L S TE + +++ V EY+ + V+ Sbjct: 68 IIRRLDHDNIVKVFEILGPSGSQLTDDVGSLTELNSVYI--VQEYMETDLANVL------ 119 Query: 148 NQRMPLI--YVKLYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKV 321 ++ PL+ + +L+ YQ+ L YIH + V HRD+KP NL +N LKI DFG A++ Sbjct: 120 -EQGPLLEEHARLFMYQLLRGLKYIH-SANVLHRDLKPANLFINTEDLVLKIGDFGLARI 177 Query: 322 LVKGEPNISY-------ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + +P+ S+ + +++YR+P L+ YT AID+W+AGC+ AE+ Sbjct: 178 M---DPHYSHKGHLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEM 225
>JNK_SUBDO (Q966Y3) Stress-activated protein kinase JNK (EC 2.7.11.24)| Length = 361 Score = 87.0 bits (214), Expect = 2e-17 Identities = 52/152 (34%), Positives = 85/152 (55%), Gaps = 1/152 (0%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELF-LNLVLEYVPETVHRVIRHYNKMNQRMPLIYVK 177 +M+++DH N++ LK+ F D+ + +V+E + + RVI + RM + Sbjct: 72 LMKMVDHKNIIGLKNLFTPAKSLDDFQDVYIVMELMDANLCRVIG-IELDHDRMSYLL-- 128 Query: 178 LYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYIC 357 YQ+ + ++H + G+ HRD+KP N++V LKI DFG A+ + Y+ Sbjct: 129 ---YQLLCGIKHLH-SAGIIHRDLKPSNIVVKEDC-SLKILDFGLARTADQTFNMTPYVV 183 Query: 358 SRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 +RYYRAPE+I G +Y +DIWS GC+ AE+ Sbjct: 184 TRYYRAPEVIVG-MKYKENVDIWSVGCIFAEM 214
>JNK1_CAEEL (Q8WQG9) Stress-activated protein kinase jnk-1 (EC 2.7.11.24)| Length = 463 Score = 87.0 bits (214), Expect = 2e-17 Identities = 52/154 (33%), Positives = 86/154 (55%), Gaps = 3/154 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELF-LNLVLEYVPETVHRVIRHYNKMNQRMPLIYVK 177 +M L++H N++ + +CF + DE L +V+E + + +VI+ M L + + Sbjct: 169 LMSLVNHKNIIGILNCFTPQKKLDEFNDLYIVMELMDANLCQVIQ--------MDLDHER 220 Query: 178 L--YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY 351 L YQ+ + ++H + G+ HRD+KP N++V LKI DFG A+ ++ Y Sbjct: 221 LSYLLYQMLCGIRHLH-SAGIIHRDLKPSNIVVRSDC-TLKILDFGLARTAIEAFMMTPY 278 Query: 352 ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + +RYYRAPE+I G Y +D+WS GC+ EL Sbjct: 279 VVTRYYRAPEVILG-MGYKENVDVWSIGCIFGEL 311
>CDC2B_ANTMA (Q38773) Cell division control protein 2 homolog B (EC 2.7.11.22)| (EC 2.7.11.23) (Fragment) Length = 280 Score = 87.0 bits (214), Expect = 2e-17 Identities = 51/154 (33%), Positives = 90/154 (58%), Gaps = 3/154 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +++ + H N+V+LK E L LV EY+ + + + + +Q + + VK+ Sbjct: 41 LLKEMHHENIVNLKDVVHR-----EKRLYLVFEYLDLDLKKHMDSCPEFSQDLHM--VKM 93 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY--- 351 + QI +AY H + V HRD+KPQNLL++ ++ +K+ DFG A+ G P ++ Sbjct: 94 FLCQILRGVAYCH-SHRVLHRDLKPQNLLIDRGSNTIKLADFGLARAF--GIPVRTFTHE 150 Query: 352 ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + + +YRAPE++ G+ Y+T +D+WS GC+ AE+ Sbjct: 151 VVTLWYRAPEVLLGSRHYSTPVDVWSVGCIFAEM 184
>PMK3_CAEEL (O44514) Mitogen-activated protein kinase pmk-3 (EC 2.7.11.24) (p38| MAP kinase 3) (Stress-activated protein kinase pmk-3) Length = 474 Score = 87.0 bits (214), Expect = 2e-17 Identities = 49/154 (31%), Positives = 89/154 (57%), Gaps = 3/154 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLI-YVK 177 +++L+ H N++ + E D + +V E+ +++++++ +R+ ++K Sbjct: 171 LLQLMRHDNIICALDIYTPDEENDFRDVYVVTEFAGRSLYQILKQQRDYGRRVLTDEHIK 230 Query: 178 LYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNIS-YI 354 YQI AL YIH + + HRD+KP NL + + L I DFG A+ L K + +++ Y+ Sbjct: 231 FIIYQIIRALKYIH-SANIIHRDLKPGNLALTDDS-DLMILDFGLARSLEKKDTSLTQYV 288 Query: 355 CSRYYRAPELIFGATE-YTTAIDIWSAGCVLAEL 453 +R+YR+PE+I+ + YT D+WS GC+ AEL Sbjct: 289 QTRWYRSPEVIYWKIDSYTNLADMWSLGCIAAEL 322
>FUS3_YEAST (P16892) Mitogen-activated protein kinase FUS3 (EC 2.7.11.24) (MAP| kinase FUS3) Length = 353 Score = 87.0 bits (214), Expect = 2e-17 Identities = 48/162 (29%), Positives = 92/162 (56%), Gaps = 11/162 (6%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +++ H N++++ + + ++ + ++ E + +HRVI Q + +++ Sbjct: 62 ILKHFKHENIITIFNIQRPDSFENFNEVYIIQELMQTDLHRVIS-----TQMLSDDHIQY 116 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNIS---- 348 + YQ A+ +H + V HRD+KP NLL+N + LK+CDFG A+++ + + S Sbjct: 117 FIYQTLRAVKVLHGS-NVIHRDLKPSNLLINSNC-DLKVCDFGLARIIDESAADNSEPTG 174 Query: 349 -------YICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 Y+ +R+YRAPE++ + +Y+ A+D+WS GC+LAEL Sbjct: 175 QQSGMTEYVATRWYRAPEVMLTSAKYSRAMDVWSCGCILAEL 216
>MK08A_CYPCA (Q90327) Mitogen-activated protein kinase 8A (EC 2.7.11.24)| (Stress-activated protein kinase JNKa) (c-Jun N-terminal kinase A) Length = 427 Score = 87.0 bits (214), Expect = 2e-17 Identities = 55/154 (35%), Positives = 86/154 (55%), Gaps = 3/154 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELF-LNLVLEYVPETVHRVIRHYNKMNQRMPLIYVK 177 +M+ ++H N++ L + F S DE + LV+E + + +VI+ M L + + Sbjct: 76 LMKYVNHKNIICLLNVFTSQKTLDEFQDVYLVMELMDANLCQVIQ--------MELDHER 127 Query: 178 L--YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY 351 L YQ+ + ++H + G+ HRD+KP N++V LKI DFG A+ G Y Sbjct: 128 LSYLLYQMLCGIKHLH-SAGIIHRDLKPSNIVVKSDC-TLKILDFGLARTAATGLLMTPY 185 Query: 352 ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + +RYYRAPE+I G Y +DIWS GC+LAE+ Sbjct: 186 VVTRYYRAPEVILG-MGYQANVDIWSVGCILAEM 218
>MK06_HUMAN (Q16659) Mitogen-activated protein kinase 6 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 3) (ERK-3) (MAP kinase isoform p97) (p97-MAPK) Length = 721 Score = 87.0 bits (214), Expect = 2e-17 Identities = 56/171 (32%), Positives = 92/171 (53%), Gaps = 20/171 (11%) Frame = +1 Query: 1 MMRLLDHPNVVS-----------LKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKM 147 ++R LDH N+V L S TE + +++ V EY+ + V+ Sbjct: 68 IIRRLDHDNIVKVFEILGPSGSQLTDDVGSLTELNSVYI--VQEYMETDLANVL------ 119 Query: 148 NQRMPLI--YVKLYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKV 321 ++ PL+ + +L+ YQ+ L YIH + V HRD+KP NL +N LKI DFG A++ Sbjct: 120 -EQGPLLEEHARLFMYQLLRGLKYIH-SANVLHRDLKPANLFINTEDLVLKIGDFGLARI 177 Query: 322 LVKGEPNISY-------ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + +P+ S+ + +++YR+P L+ YT AID+W+AGC+ AE+ Sbjct: 178 M---DPHYSHKGHLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEM 225
>CDC21_MEDSA (P24923) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| (EC 2.7.11.23) (Fragment) Length = 291 Score = 87.0 bits (214), Expect = 2e-17 Identities = 53/158 (33%), Positives = 87/158 (55%), Gaps = 7/158 (4%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLI---- 168 +++ + H N+V L+ S L LV EY+ + + M+ I Sbjct: 51 LLKEMQHRNIVRLQDVVHSDKR-----LYLVFEYLDLDLKK------HMDSSPEFIKDPR 99 Query: 169 YVKLYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNIS 348 VK++ YQ+ +AY H + V HRD+KPQNLL++ T+ LK+ DFG A+ G P + Sbjct: 100 QVKMFLYQMLCGIAYCH-SHRVLHRDLKPQNLLIDRRTNSLKLADFGLARAF--GIPVRT 156 Query: 349 Y---ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + + + +YRAPE++ G+ Y+T +D+WS GC+ AE+ Sbjct: 157 FTHEVVTLWYRAPEILLGSRHYSTPVDVWSVGCIFAEM 194
>CDKL2_MOUSE (Q9QUK0) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| (Serine/threonine-protein kinase KKIAMRE) Length = 568 Score = 86.7 bits (213), Expect = 3e-17 Identities = 52/153 (33%), Positives = 92/153 (60%), Gaps = 2/153 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHY-NKMNQRMPLIYVK 177 +++ L H N+V+L +K + + LV E+V T+ ++ + N ++ ++ V+ Sbjct: 54 LLKQLRHENLVNL----LEVCKKKKRWY-LVFEFVDHTILDDLKLFPNGLDYQV----VQ 104 Query: 178 LYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVK-GEPNISYI 354 Y +QI + + H + + HRDIKP+N+LV+ + +K+CDFG A+ L GE Y+ Sbjct: 105 KYLFQIINGIGFCH-SHNIIHRDIKPENILVS-QSGVVKLCDFGFARTLAAPGEVYTDYV 162 Query: 355 CSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 +R+YRAPEL+ G +Y A+DIW+ GC++ E+ Sbjct: 163 ATRWYRAPELLVGDVKYGKAVDIWAIGCLVIEM 195
>MK12_HUMAN (P53778) Mitogen-activated protein kinase 12 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 6) (ERK-6) (ERK5) (Stress-activated protein kinase 3) (Mitogen-activated protein kinase p38 gamma) (MAP kinase p38 gamma) Length = 367 Score = 86.7 bits (213), Expect = 3e-17 Identities = 51/152 (33%), Positives = 80/152 (52%), Gaps = 1/152 (0%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELF-LNLVLEYVPETVHRVIRHYNKMNQRMPLIYVK 177 +++ + H NV+ L F D+ LV+ ++ + ++++H R+ + Sbjct: 77 LLKHMRHENVIGLLDVFTPDETLDDFTDFYLVMPFMGTDLGKLMKHEKLGEDRIQFLV-- 134 Query: 178 LYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYIC 357 YQ+ L YIH G+ HRD+KP NL VN +LKI DFG A+ Y+ Sbjct: 135 ---YQMLKGLRYIH-AAGIIHRDLKPGNLAVNEDC-ELKILDFGLARQA--DSEMTGYVV 187 Query: 358 SRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 +R+YRAPE+I YT +DIWS GC++AE+ Sbjct: 188 TRWYRAPEVILNWMRYTQTVDIWSVGCIMAEM 219
>CDK5_RAT (Q03114) Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein| kinase II catalytic subunit) (TPKII catalytic subunit) (Serine/threonine-protein kinase PSSALRE) Length = 292 Score = 86.7 bits (213), Expect = 3e-17 Identities = 54/154 (35%), Positives = 85/154 (55%), Gaps = 3/154 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +++ L H N+V L S + L LV E+ + + + +++ N + VK Sbjct: 54 LLKELKHKNIVRLHDVLHSDKK-----LTLVFEFCDQDLKK---YFDSCNGDLDPEIVKS 105 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY--- 351 +Q+ L + H V HRD+KPQNLL+N +LK+ DFG A+ G P Y Sbjct: 106 LLFQLLKGLGFCHSR-NVLHRDLKPQNLLIN-RNGELKLADFGLARAF--GIPVRCYSAE 161 Query: 352 ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + + +YR P+++FGA Y+T+ID+WSAGC+ AEL Sbjct: 162 VVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAEL 195
>CDKL2_RAT (Q5XIT0) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| Length = 507 Score = 86.7 bits (213), Expect = 3e-17 Identities = 52/153 (33%), Positives = 92/153 (60%), Gaps = 2/153 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHY-NKMNQRMPLIYVK 177 +++ L H N+V+L +K + + LV E+V T+ ++ + N ++ ++ V+ Sbjct: 54 LLKQLRHENLVNL----LEVCKKKKRWY-LVFEFVDHTILDDLKLFPNGLDYQV----VQ 104 Query: 178 LYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVK-GEPNISYI 354 Y +QI + + H + + HRDIKP+N+LV+ + +K+CDFG A+ L GE Y+ Sbjct: 105 KYLFQIINGIGFCH-SHNIIHRDIKPENILVS-QSGVVKLCDFGFARTLAAPGEVYTDYV 162 Query: 355 CSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 +R+YRAPEL+ G +Y A+DIW+ GC++ E+ Sbjct: 163 ATRWYRAPELLVGDVKYGKAVDIWAIGCLVIEM 195
>CDK2_ENTHI (Q04770) Cell division protein kinase 2 homolog (EC 2.7.11.22)| Length = 291 Score = 86.3 bits (212), Expect = 3e-17 Identities = 52/148 (35%), Positives = 83/148 (56%), Gaps = 1/148 (0%) Frame = +1 Query: 13 LDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKLYSYQ 192 L HPNVV L + ++ FL LV E+ E +++ + +K+ P+ + YQ Sbjct: 58 LKHPNVVDLYDIYL-----EDKFLYLVFEFCDEDLYQFMSRSSKI----PINETRSIVYQ 108 Query: 193 ICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVL-VKGEPNISYICSRYY 369 I LA+ H + HRD+KPQN+L+N + +K+ +FG A++ + S + + +Y Sbjct: 109 ILQGLAFCHYHQ-ILHRDMKPQNILINKNG-TIKLGEFGLARLTTINDRKYTSEVVTLWY 166 Query: 370 RAPELIFGATEYTTAIDIWSAGCVLAEL 453 RAPE++ GAT+Y AIDIWS + EL Sbjct: 167 RAPEILLGATQYGGAIDIWSTAAIFGEL 194
>CDKL2_MACFA (Q4R7T5) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| Length = 570 Score = 86.3 bits (212), Expect = 3e-17 Identities = 50/152 (32%), Positives = 86/152 (56%), Gaps = 1/152 (0%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +++ L H N+V+L +K + + LV E+V H ++ + V+ Sbjct: 54 LLKQLRHENLVNL----LEVCKKKKRWY-LVFEFVD---HTILDDLELFPNGLDYQVVQK 105 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVK-GEPNISYIC 357 Y +QI + + H + + HRDIKP+N+LV+ + +K+CDFG A+ L GE Y+ Sbjct: 106 YLFQIINGIGFCH-SHNIIHRDIKPENILVS-QSGVVKLCDFGFARTLAAPGEVYTDYVA 163 Query: 358 SRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 +R+YRAPEL+ G +Y A+D+W+ GC++ E+ Sbjct: 164 TRWYRAPELLVGDVKYGKAVDVWAIGCLVTEM 195
>MK14B_BRARE (Q9DGE1) Mitogen-activated protein kinase 14b (EC 2.7.11.24)| (Mitogen-activated protein kinase p38b) (MAP kinase p38b) (zp38b) Length = 348 Score = 86.3 bits (212), Expect = 3e-17 Identities = 51/152 (33%), Positives = 83/152 (54%), Gaps = 1/152 (0%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELF-LNLVLEYVPETVHRVIRHYNKMNQRMPLIYVK 177 +++ + H NV+ L F T + + LV + ++ +++ Q++ +V+ Sbjct: 75 LLKHMKHENVIGLLDVFSPATSLEGFNDVYLVTHLMGADLNNIVKC-----QKLTDDHVQ 129 Query: 178 LYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYIC 357 YQI AL YIH + + HRD+KP NL VN +LKI DFG A++ + Y+ Sbjct: 130 FLIYQILRALKYIH-SADIIHRDLKPSNLAVNEDC-ELKILDFGLARLT--DDEMTGYVA 185 Query: 358 SRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 +R+YRAPE++ Y +DIWS GC++AEL Sbjct: 186 TRWYRAPEIMLNWMHYNMTVDIWSVGCIMAEL 217
>CDKL2_RABIT (Q9TTK0) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| (Serine/threonine-protein kinase KKIAMRE) Length = 566 Score = 86.3 bits (212), Expect = 3e-17 Identities = 51/153 (33%), Positives = 91/153 (59%), Gaps = 2/153 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHY-NKMNQRMPLIYVK 177 +++ L H N+V+L +K + + LV E+V T+ + + N ++ ++ V+ Sbjct: 54 LLKQLRHENLVNL----LEVCKKKKRWY-LVFEFVDHTILDDLELFPNGLDDQV----VQ 104 Query: 178 LYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVK-GEPNISYI 354 Y +QI + + H + + HRDIKP+N+LV+ + +K+CDFG A+ L GE Y+ Sbjct: 105 KYLFQIINGIGFCH-SHNIIHRDIKPENILVS-QSGVVKLCDFGFARTLAAPGEVYTDYV 162 Query: 355 CSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 +R+YRAPEL+ G +Y A+D+W+ GC++ E+ Sbjct: 163 ATRWYRAPELLVGDVKYGKAVDVWAIGCLVTEM 195
>CDKL2_HUMAN (Q92772) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| (Serine/threonine-protein kinase KKIAMRE) (Protein kinase p56 KKIAMRE) Length = 493 Score = 86.3 bits (212), Expect = 3e-17 Identities = 50/152 (32%), Positives = 86/152 (56%), Gaps = 1/152 (0%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +++ L H N+V+L +K + + LV E+V H ++ + V+ Sbjct: 54 LLKQLRHENLVNL----LEVCKKKKRWY-LVFEFVD---HTILDDLELFPNGLDYQVVQK 105 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVK-GEPNISYIC 357 Y +QI + + H + + HRDIKP+N+LV+ + +K+CDFG A+ L GE Y+ Sbjct: 106 YLFQIINGIGFCH-SHNIIHRDIKPENILVS-QSGVVKLCDFGFARTLAAPGEVYTDYVA 163 Query: 358 SRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 +R+YRAPEL+ G +Y A+D+W+ GC++ E+ Sbjct: 164 TRWYRAPELLVGDVKYGKAVDVWAIGCLVTEM 195
>CDKL2_PONPY (Q5R754) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| Length = 493 Score = 85.9 bits (211), Expect = 4e-17 Identities = 50/152 (32%), Positives = 86/152 (56%), Gaps = 1/152 (0%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +++ L H N+V+L +K + + LV E+V H ++ + V+ Sbjct: 54 LLKQLRHENLVNL----LEVCKKKKRWY-LVFEFVD---HTILDDLELFPNGLDYQVVQK 105 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVK-GEPNISYIC 357 Y +QI + + H + + HRDIKP+N+LV+ + +K+CDFG A+ L GE Y+ Sbjct: 106 YLFQIINGIGFCH-SHNIIHRDIKPENILVSK-SGVVKLCDFGFARTLAAPGEVYTDYVA 163 Query: 358 SRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 +R+YRAPEL+ G +Y A+D+W+ GC++ E+ Sbjct: 164 TRWYRAPELLVGDVKYGKAVDVWAIGCLVTEM 195
>MK14A_CYPCA (Q90336) Mitogen-activated protein kinase 14a (EC 2.7.11.24)| (Mitogen-activated protein kinase p38a) (MAP kinase p38a) (cp38a) Length = 361 Score = 85.9 bits (211), Expect = 4e-17 Identities = 51/152 (33%), Positives = 82/152 (53%), Gaps = 1/152 (0%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELF-LNLVLEYVPETVHRVIRHYNKMNQRMPLIYVK 177 +++ + H NV+ L F T +E + LV + ++ +++ Q++ +V+ Sbjct: 75 LLKHMKHENVIGLLDVFTPATSLEEFNDVYLVTHLMGADLNNIVKC-----QKLTDDHVQ 129 Query: 178 LYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYIC 357 YQI L YIH + + HRD+KP NL VN +LKI DFG A+ + Y+ Sbjct: 130 FLIYQILRGLKYIH-SADIIHRDLKPSNLAVNEDC-ELKILDFGLARHT--DDEMTGYVA 185 Query: 358 SRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 +R+YRAPE++ Y +DIWS GC++AEL Sbjct: 186 TRWYRAPEIMLNWMHYNMTVDIWSVGCIMAEL 217
>MK11_HUMAN (Q15759) Mitogen-activated protein kinase 11 (EC 2.7.11.24)| (Mitogen-activated protein kinase p38 beta) (MAP kinase p38 beta) (p38b) (p38-2) (Stress-activated protein kinase 2) Length = 372 Score = 85.9 bits (211), Expect = 4e-17 Identities = 51/155 (32%), Positives = 83/155 (53%), Gaps = 4/155 (2%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELF-LNLVLEYVPETVHRVIRHYNKMNQRMPLI--- 168 +++ L H NV+ L F T ++ + LV + ++ +++ +Q L Sbjct: 74 LLKHLKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQAGAHQGARLALDE 133 Query: 169 YVKLYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNIS 348 +V+ YQ+ L YIH + G+ HRD+KP N+ VN +L+I DFG A+ E Sbjct: 134 HVQFLVYQLLRGLKYIH-SAGIIHRDLKPSNVAVNEDC-ELRILDFGLARQA--DEEMTG 189 Query: 349 YICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 Y+ +R+YRAPE++ Y +DIWS GC++AEL Sbjct: 190 YVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAEL 224
>PCTK1_RAT (Q63686) Serine/threonine-protein kinase PCTAIRE-1 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 1) Length = 496 Score = 85.9 bits (211), Expect = 4e-17 Identities = 54/154 (35%), Positives = 87/154 (56%), Gaps = 3/154 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +++ L H N+V+L TEK L LV EY+ + + + + + + + VKL Sbjct: 214 LLKDLKHANIVTLHDIIH--TEKS---LTLVFEYLDKDLKQYLDDCGNV---INMHNVKL 265 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY--- 351 + +Q+ LAY HR V HRD+KPQNLL+N +LK+ DFG A K P +Y Sbjct: 266 FLFQLLRGLAYCHRQK-VLHRDLKPQNLLINERG-ELKLADFGLA--YAKSIPTKTYSNE 321 Query: 352 ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + + +YR P+++ G+T+Y+ ID+W GC+ E+ Sbjct: 322 VVTLWYRPPDILLGSTDYSGQIDMWGVGCIFYEM 355
>MK12_BRARE (O42376) Mitogen-activated protein kinase 12 (EC 2.7.11.24)| (Stress-activated protein kinase 3) Length = 363 Score = 85.5 bits (210), Expect = 6e-17 Identities = 50/152 (32%), Positives = 80/152 (52%), Gaps = 1/152 (0%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELF-LNLVLEYVPETVHRVIRHYNKMNQRMPLIYVK 177 +++ + H NV+ L F + D LV+ ++ + ++++ +R V+ Sbjct: 75 LLKHMKHDNVIGLVDVFTADLSLDRFHDFYLVMPFMGTDLGKLMKMERLSEER-----VQ 129 Query: 178 LYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYIC 357 YQ+ L YIH G+ HRD+KP NL +N +LKI DFG A+ Y+ Sbjct: 130 YLVYQMLKGLKYIH-AAGIIHRDLKPGNLAINEEC-ELKILDFGLARQT--DSEMTGYVV 185 Query: 358 SRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 +R+YRAPE+I YT +DIWS GC++AE+ Sbjct: 186 TRWYRAPEVILSWMHYTQTVDIWSVGCIMAEM 217
>YPC2_CAEEL (Q11179) Putative serine/threonine-protein kinase C05D10.2 in| chromosome III (EC 2.7.11.24) Length = 470 Score = 85.5 bits (210), Expect = 6e-17 Identities = 48/154 (31%), Positives = 89/154 (57%), Gaps = 9/154 (5%) Frame = +1 Query: 19 HPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKLYSYQIC 198 HPNV+ L + F + ++D + L E++ +H VI+ + + ++ + Q+ Sbjct: 70 HPNVIKLYNIFRADNDRD---IYLAFEFMEADLHNVIKKGSILKD----VHKQYIMCQLF 122 Query: 199 XALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGE--------PNIS-Y 351 A+ ++H + V HRD+KP N+L++ ++K+ DFG A+ L E P+++ Y Sbjct: 123 RAIRFLH-SGNVLHRDLKPSNVLLDADC-RVKLADFGLARSLSSLEDYPEGQKMPDLTEY 180 Query: 352 ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + +R+YR+PE++ A YT +D+WS GC+LAE+ Sbjct: 181 VATRWYRSPEILLAAKRYTKGVDMWSLGCILAEM 214
>CDC28_YEAST (P00546) Cell division control protein 28 (EC 2.7.11.22)| Length = 298 Score = 85.5 bits (210), Expect = 6e-17 Identities = 55/154 (35%), Positives = 85/154 (55%), Gaps = 3/154 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +++ L N+V L S K L LV E++ + R + K +Q + VK Sbjct: 61 LLKELKDDNIVRLYDIVHSDAHK----LYLVFEFLDLDLKRYMEGIPK-DQPLGADIVKK 115 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY--- 351 + Q+C +AY H + + HRD+KPQNLL+N + LK+ DFG A+ G P +Y Sbjct: 116 FMMQLCKGIAYCH-SHRILHRDLKPQNLLINKDGN-LKLGDFGLARAF--GVPLRAYTHE 171 Query: 352 ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 I + +YRAPE++ G +Y+T +D WS GC+ AE+ Sbjct: 172 IVTLWYRAPEVLLGGKQYSTGVDTWSIGCIFAEM 205
>JNK1_ANCCA (Q9U6D2) Stress-activated protein kinase JNK-1 (EC 2.7.11.24)| Length = 376 Score = 85.1 bits (209), Expect = 7e-17 Identities = 53/154 (34%), Positives = 85/154 (55%), Gaps = 3/154 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELF-LNLVLEYVPETVHRVIRHYNKMNQRMPLIYVK 177 +M L++H N++ L + F E +E L +V+E + + +VI+ M L + + Sbjct: 76 LMNLVNHKNIIGLLNAFSPQREVEEFNDLYIVMELMDANLCQVIQ--------MDLDHER 127 Query: 178 L--YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY 351 L YQ+ + ++H + G+ HRD+KP N++V LKI DFG A+ V+ Y Sbjct: 128 LSYLLYQMLCGIKHLH-SAGIIHRDLKPSNIVVKSDC-TLKILDFGLARTAVEAFMMTPY 185 Query: 352 ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + +RYYRAPE+I G Y +D+WS GC+ EL Sbjct: 186 VVTRYYRAPEVILG-MGYGENVDVWSVGCIFGEL 218
>MK14A_DROME (O62618) Mitogen-activated protein kinase 14A (EC 2.7.11.24) (MAP| kinase p38a) (p38 MAPK) (Dp38) (D-p38a) Length = 366 Score = 85.1 bits (209), Expect = 7e-17 Identities = 53/155 (34%), Positives = 80/155 (51%), Gaps = 4/155 (2%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELF----LNLVLEYVPETVHRVIRHYNKMNQRMPLI 168 +++ +DH NV+ L F L + LV + ++ +IR Q + Sbjct: 75 LLKHMDHENVIGLLDIFHPHPANGSLENFQQVYLVTHLMDADLNNIIRM-----QHLSDD 129 Query: 169 YVKLYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNIS 348 +V+ YQI L YIH + GV HRD+KP N+ VN +L+I DFG A+ Sbjct: 130 HVQFLVYQILRGLKYIH-SAGVIHRDLKPSNIAVNEDC-ELRILDFGLARPTEN--EMTG 185 Query: 349 YICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 Y+ +R+YRAPE++ Y +DIWS GC++AEL Sbjct: 186 YVATRWYRAPEIMLNWMHYDQTVDIWSVGCIMAEL 220
>SPM1_SCHPO (Q92398) Mitogen-activated protein kinase spm1 (EC 2.7.11.24) (MAP| kinase spm1) (MAP kinase pmk1) Length = 422 Score = 85.1 bits (209), Expect = 7e-17 Identities = 48/109 (44%), Positives = 65/109 (59%), Gaps = 5/109 (4%) Frame = +1 Query: 142 KMNQRMPLIYVKLYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKV 321 K Q + + + + YQI L YIH + V HRD+KP NLLVN +LKICDFG A+ Sbjct: 116 KSGQPLTDAHFQSFIYQILCGLKYIH-SANVIHRDLKPGNLLVNADC-ELKICDFGLARG 173 Query: 322 LVKG-EPN----ISYICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + E N Y+ +R+YRAPE++ + Y ID+WS GC+LAEL Sbjct: 174 CSENPEENPGFMTEYVATRWYRAPEIMLSFSSYHKGIDVWSVGCILAEL 222
>MK14A_BRARE (Q9DGE2) Mitogen-activated protein kinase 14a (EC 2.7.11.24)| (Mitogen-activated protein kinase p38a) (MAP kinase p38a) (zp38a) Length = 361 Score = 84.7 bits (208), Expect = 1e-16 Identities = 51/152 (33%), Positives = 81/152 (53%), Gaps = 1/152 (0%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELF-LNLVLEYVPETVHRVIRHYNKMNQRMPLIYVK 177 +++ + H NV+ L F T E + LV + ++ +++ Q++ +V+ Sbjct: 75 LLKHMRHENVIGLLDVFTPATSLKEFNDVYLVTHLMGADLNNIVKC-----QKLTDDHVQ 129 Query: 178 LYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYIC 357 YQI L YIH + + HRD+KP NL VN +LKI DFG A+ + Y+ Sbjct: 130 FLIYQILRGLKYIH-SADIIHRDLKPSNLAVNEDC-ELKILDFGLARHT--DDEMTGYVA 185 Query: 358 SRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 +R+YRAPE++ Y +DIWS GC++AEL Sbjct: 186 TRWYRAPEIMLNWMHYNVTVDIWSVGCIMAEL 217
>CDC22_XENLA (P24033) Cell division control protein 2 homolog 2 (EC 2.7.11.22)| (EC 2.7.11.23) (p34 protein kinase 2) Length = 302 Score = 84.7 bits (208), Expect = 1e-16 Identities = 52/154 (33%), Positives = 84/154 (54%), Gaps = 3/154 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +++ L HPN+V C +D L L+ E++ V + + Q + + VK Sbjct: 54 LLKELQHPNIV----CLLDVLMQDSR-LYLIFEFLSMDVKKYLDSIPS-GQYIDTMLVKS 107 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY--- 351 Y YQI + + H GV HRD+KPQNLL++ + +K+ DFG A+ G P Y Sbjct: 108 YLYQILQGIVFCHSR-GVLHRDLKPQNLLID-NKGVIKLADFGLARAF--GIPVRVYTHE 163 Query: 352 ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + + +YRAPE++ G+ Y+T +D+WS G + AE+ Sbjct: 164 VVTLWYRAPEVLLGSVRYSTPVDVWSVGTIFAEI 197
>MK09_MOUSE (Q9WTU6) Mitogen-activated protein kinase 9 (EC 2.7.11.24)| (Stress-activated protein kinase JNK2) (c-Jun N-terminal kinase 2) Length = 423 Score = 84.3 bits (207), Expect = 1e-16 Identities = 51/152 (33%), Positives = 85/152 (55%), Gaps = 1/152 (0%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELF-LNLVLEYVPETVHRVIRHYNKMNQRMPLIYVK 177 +++ ++H N++SL + F +E + LV+E + + +VI H ++RM + Sbjct: 76 LLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVI-HMELDHERMSYLL-- 132 Query: 178 LYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYIC 357 YQ+ + ++H + G+ HRD+KP N++V LKI DFG A+ Y+ Sbjct: 133 ---YQMLCGIKHLH-SAGIIHRDLKPSNIVVKSDC-TLKILDFGLARTACTNFMMTPYVV 187 Query: 358 SRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 +RYYRAPE+I G Y +DIWS GC++AE+ Sbjct: 188 TRYYRAPEVILG-MGYKENVDIWSVGCIMAEM 218
>MK09_CHICK (P79996) Mitogen-activated protein kinase 9 (EC 2.7.11.24)| (Stress-activated protein kinase JNK2) (c-Jun N-terminal kinase 2) Length = 382 Score = 84.0 bits (206), Expect = 2e-16 Identities = 51/152 (33%), Positives = 84/152 (55%), Gaps = 1/152 (0%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELF-LNLVLEYVPETVHRVIRHYNKMNQRMPLIYVK 177 +++ ++H N++SL + F +E + LV+E + + +VI H ++RM + Sbjct: 76 LLKCVNHKNIISLLNVFTPQKSLEEFQDVYLVMELMDANLCQVI-HMELDHERMSYLL-- 132 Query: 178 LYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYIC 357 YQ+ + ++H + G+ HRD+KP N++V LKI DFG A+ Y+ Sbjct: 133 ---YQMLCGIKHLH-SAGIIHRDLKPSNIVVKSDC-TLKILDFGLARTACTNFMMTPYVV 187 Query: 358 SRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 +RYYRAPE+I G Y +DIWS GC++ EL Sbjct: 188 TRYYRAPEVILG-MGYKENVDIWSVGCIMGEL 218
>PMK2_CAEEL (Q8MXI4) Mitogen-activated protein kinase pmk-2 (EC 2.7.11.24) (p38| MAP kinase 2) (Stress-activated protein kinase pmk-2) Length = 419 Score = 84.0 bits (206), Expect = 2e-16 Identities = 55/167 (32%), Positives = 84/167 (50%), Gaps = 16/167 (9%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 ++R L H NV+ + F T + D LN V +V + +++ K+ QR+ ++L Sbjct: 99 LLRTLQHDNVLEMIDVF--TPDPDASSLNNVY-FVSVLMGSDLQNIMKI-QRLTDEQIQL 154 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQ----------------LKICDFGS 312 YQ+ L YIH + G+ HRD+KP N+ VN KI DFG Sbjct: 155 LIYQVLRGLKYIH-SAGIIHRDLKPSNIAVNERCEVKVFLSFSQLSFLILSFFKILDFGL 213 Query: 313 AKVLVKGEPNISYICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 A+ + Y+ +R+YRAPE++ YT +D+WS GC+LAEL Sbjct: 214 ARA--QDAEMTGYVATRWYRAPEIMLNWMHYTQTVDVWSVGCILAEL 258
>MK11_MOUSE (Q9WUI1) Mitogen-activated protein kinase 11 (EC 2.7.11.24)| (Mitogen-activated protein kinase p38 beta) (MAP kinase p38 beta) (p38B) Length = 364 Score = 84.0 bits (206), Expect = 2e-16 Identities = 50/152 (32%), Positives = 81/152 (53%), Gaps = 1/152 (0%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELF-LNLVLEYVPETVHRVIRHYNKMNQRMPLIYVK 177 +++ L H NV+ L F T ++ + LV + ++ +++ Q + +V+ Sbjct: 74 LLKHLKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKC-----QALSDEHVQ 128 Query: 178 LYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYIC 357 YQ+ L YIH + G+ HRD+KP N+ VN +L+I DFG A E Y+ Sbjct: 129 FLVYQLLRGLKYIH-SAGIIHRDLKPSNVAVNEDC-ELRILDFGLAPQA--DEEMTGYVA 184 Query: 358 SRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 +R+YRAPE++ Y +DIWS GC++AEL Sbjct: 185 TRWYRAPEIMLNWMHYNQTVDIWSVGCIMAEL 216
>PRP4B_MOUSE (Q61136) Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1)| (PRP4 pre-mRNA-processing factor 4 homolog) (Pre-mRNA protein kinase) Length = 1007 Score = 84.0 bits (206), Expect = 2e-16 Identities = 51/124 (41%), Positives = 71/124 (57%) Frame = +1 Query: 82 LNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKLYSYQICXALAYIHRTVGVCHRDIKPQN 261 L LV E + + V++ Y K + + + V+ YS Q+ AL + R + H DIKP N Sbjct: 763 LCLVFEPLSMNLREVLKKYGK-DVGLHIKAVRSYSQQLFLALKLLKRC-NILHADIKPDN 820 Query: 262 LLVNPHTHQLKICDFGSAKVLVKGEPNISYICSRYYRAPELIFGATEYTTAIDIWSAGCV 441 +LVN LK+CDFGSA + + Y+ SR+YRAPE+I G + Y ID+WS GC Sbjct: 821 ILVNESKTILKLCDFGSASHVADNDIT-PYLVSRFYRAPEIIIGKS-YDYGIDMWSVGCT 878 Query: 442 LAEL 453 L EL Sbjct: 879 LYEL 882
>PRP4B_HUMAN (Q13523) Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1)| (PRP4 pre-mRNA-processing factor 4 homolog) (PRP4 kinase) Length = 1007 Score = 84.0 bits (206), Expect = 2e-16 Identities = 51/124 (41%), Positives = 71/124 (57%) Frame = +1 Query: 82 LNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKLYSYQICXALAYIHRTVGVCHRDIKPQN 261 L LV E + + V++ Y K + + + V+ YS Q+ AL + R + H DIKP N Sbjct: 763 LCLVFEPLSMNLREVLKKYGK-DVGLHIKAVRSYSQQLFLALKLLKRC-NILHADIKPDN 820 Query: 262 LLVNPHTHQLKICDFGSAKVLVKGEPNISYICSRYYRAPELIFGATEYTTAIDIWSAGCV 441 +LVN LK+CDFGSA + + Y+ SR+YRAPE+I G + Y ID+WS GC Sbjct: 821 ILVNESKTILKLCDFGSASHVADNDIT-PYLVSRFYRAPEIIIGKS-YDYGIDMWSVGCT 878 Query: 442 LAEL 453 L EL Sbjct: 879 LYEL 882
>PMK1_CAEEL (Q17446) Mitogen-activated protein kinase pmk-1 (EC 2.7.11.24) (p38| MAP kinase 1) (Stress-activated protein kinase pmk-1) Length = 377 Score = 84.0 bits (206), Expect = 2e-16 Identities = 49/155 (31%), Positives = 81/155 (52%), Gaps = 4/155 (2%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTE----KDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLI 168 ++R + H N++ L F +D F+++++ + ++ QR+ Sbjct: 85 LLRCMCHENIIDLLDVFTPNENVNDIEDVYFVSMLMGADLSNILKI--------QRLNDD 136 Query: 169 YVKLYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNIS 348 +++ YQI L YIH + + HRD+KP N+ VN +LKI DFG A+ Sbjct: 137 HIQFLVYQILRGLKYIH-SADIIHRDLKPSNIAVNEDC-ELKILDFGLARQT--DSEMTG 192 Query: 349 YICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 Y+ +R+YRAPE++ YT +D+WS GC+LAEL Sbjct: 193 YVATRWYRAPEIMLNWMHYTQTVDVWSVGCILAEL 227
>MK09_RAT (P49186) Mitogen-activated protein kinase 9 (EC 2.7.11.24)| (Stress-activated protein kinase JNK2) (c-Jun N-terminal kinase 2) (SAPK-alpha) (p54-alpha) Length = 423 Score = 83.6 bits (205), Expect = 2e-16 Identities = 51/152 (33%), Positives = 84/152 (55%), Gaps = 1/152 (0%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELF-LNLVLEYVPETVHRVIRHYNKMNQRMPLIYVK 177 +++ ++H N++SL + F +E + LV+E + + +VI H ++RM + Sbjct: 76 LLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVI-HMELDHERMSYLL-- 132 Query: 178 LYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYIC 357 YQ+ + ++H + G+ HRD+KP N++V LKI DFG A+ Y+ Sbjct: 133 ---YQMLCGIKHLH-SAGIIHRDLKPSNIVVKSDC-TLKILDFGLARTACTNFMMTPYVV 187 Query: 358 SRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 +RYYRAPE+I G Y +DIWS GC++ EL Sbjct: 188 TRYYRAPEVILG-MGYKENVDIWSVGCIMGEL 218
>MK09_HUMAN (P45984) Mitogen-activated protein kinase 9 (EC 2.7.11.24)| (Stress-activated protein kinase JNK2) (c-Jun N-terminal kinase 2) (JNK-55) Length = 424 Score = 83.6 bits (205), Expect = 2e-16 Identities = 51/152 (33%), Positives = 84/152 (55%), Gaps = 1/152 (0%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELF-LNLVLEYVPETVHRVIRHYNKMNQRMPLIYVK 177 +++ ++H N++SL + F +E + LV+E + + +VI H ++RM + Sbjct: 76 LLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVI-HMELDHERMSYLL-- 132 Query: 178 LYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYIC 357 YQ+ + ++H + G+ HRD+KP N++V LKI DFG A+ Y+ Sbjct: 133 ---YQMLCGIKHLH-SAGIIHRDLKPSNIVVKSDC-TLKILDFGLARTACTNFMMTPYVV 187 Query: 358 SRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 +RYYRAPE+I G Y +DIWS GC++ EL Sbjct: 188 TRYYRAPEVILG-MGYKENVDIWSVGCIMGEL 218
>MK14_RAT (P70618) Mitogen-activated protein kinase 14 (EC 2.7.11.24)| (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (CRK1) Length = 359 Score = 83.6 bits (205), Expect = 2e-16 Identities = 50/152 (32%), Positives = 81/152 (53%), Gaps = 1/152 (0%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELF-LNLVLEYVPETVHRVIRHYNKMNQRMPLIYVK 177 +++ + H NV+ L F +E + LV + ++ +++ Q++ +V+ Sbjct: 73 LLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKC-----QKLTDDHVQ 127 Query: 178 LYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYIC 357 YQI L YIH + + HRD+KP NL VN +LKI DFG A+ + Y+ Sbjct: 128 FLIYQILRGLKYIH-SADIIHRDLKPSNLAVNEDC-ELKILDFGLARHT--DDEMTGYVA 183 Query: 358 SRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 +R+YRAPE++ Y +DIWS GC++AEL Sbjct: 184 TRWYRAPEIMLNWMHYNQTVDIWSVGCIMAEL 215
>MK14_PANTR (Q95NE7) Mitogen-activated protein kinase 14 (EC 2.7.11.24)| (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (Stress-activated protein kinase 2a) Length = 359 Score = 83.6 bits (205), Expect = 2e-16 Identities = 50/152 (32%), Positives = 81/152 (53%), Gaps = 1/152 (0%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELF-LNLVLEYVPETVHRVIRHYNKMNQRMPLIYVK 177 +++ + H NV+ L F +E + LV + ++ +++ Q++ +V+ Sbjct: 73 LLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKC-----QKLTDDHVQ 127 Query: 178 LYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYIC 357 YQI L YIH + + HRD+KP NL VN +LKI DFG A+ + Y+ Sbjct: 128 FLIYQILRGLKYIH-SADIIHRDLKPSNLAVNEDC-ELKILDFGLARHT--DDEMTGYVA 183 Query: 358 SRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 +R+YRAPE++ Y +DIWS GC++AEL Sbjct: 184 TRWYRAPEIMLNWMHYNQTVDIWSVGCIMAEL 215
>MK14_MOUSE (P47811) Mitogen-activated protein kinase 14 (EC 2.7.11.24)| (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (CRK1) Length = 359 Score = 83.6 bits (205), Expect = 2e-16 Identities = 50/152 (32%), Positives = 81/152 (53%), Gaps = 1/152 (0%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELF-LNLVLEYVPETVHRVIRHYNKMNQRMPLIYVK 177 +++ + H NV+ L F +E + LV + ++ +++ Q++ +V+ Sbjct: 73 LLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKC-----QKLTDDHVQ 127 Query: 178 LYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYIC 357 YQI L YIH + + HRD+KP NL VN +LKI DFG A+ + Y+ Sbjct: 128 FLIYQILRGLKYIH-SADIIHRDLKPSNLAVNEDC-ELKILDFGLARHT--DDEMTGYVA 183 Query: 358 SRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 +R+YRAPE++ Y +DIWS GC++AEL Sbjct: 184 TRWYRAPEIMLNWMHYNQTVDIWSVGCIMAEL 215
>MK14_HUMAN (Q16539) Mitogen-activated protein kinase 14 (EC 2.7.11.24)| (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (Cytokine suppressive anti-inflammatory drug-binding protein) (CSAID-binding protein) (CSBP) (MAX-interacting prote Length = 359 Score = 83.6 bits (205), Expect = 2e-16 Identities = 50/152 (32%), Positives = 81/152 (53%), Gaps = 1/152 (0%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELF-LNLVLEYVPETVHRVIRHYNKMNQRMPLIYVK 177 +++ + H NV+ L F +E + LV + ++ +++ Q++ +V+ Sbjct: 73 LLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKC-----QKLTDDHVQ 127 Query: 178 LYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYIC 357 YQI L YIH + + HRD+KP NL VN +LKI DFG A+ + Y+ Sbjct: 128 FLIYQILRGLKYIH-SADIIHRDLKPSNLAVNEDC-ELKILDFGLARHT--DDEMTGYVA 183 Query: 358 SRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 +R+YRAPE++ Y +DIWS GC++AEL Sbjct: 184 TRWYRAPEIMLNWMHYNQTVDIWSVGCIMAEL 215
>MK14_CANFA (O02812) Mitogen-activated protein kinase 14 (EC 2.7.11.24)| (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) Length = 359 Score = 83.6 bits (205), Expect = 2e-16 Identities = 50/152 (32%), Positives = 81/152 (53%), Gaps = 1/152 (0%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELF-LNLVLEYVPETVHRVIRHYNKMNQRMPLIYVK 177 +++ + H NV+ L F +E + LV + ++ +++ Q++ +V+ Sbjct: 73 LLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKC-----QKLTDDHVQ 127 Query: 178 LYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYIC 357 YQI L YIH + + HRD+KP NL VN +LKI DFG A+ + Y+ Sbjct: 128 FLIYQILRGLKYIH-SADIIHRDLKPSNLAVNEDC-ELKILDFGLARHT--DDEMTGYVA 183 Query: 358 SRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 +R+YRAPE++ Y +DIWS GC++AEL Sbjct: 184 TRWYRAPEIMLNWMHYNQTVDIWSVGCIMAEL 215
>MK04_RAT (Q63454) Mitogen-activated protein kinase 4 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 4) (ERK-4) (MAP kinase isoform p63) (p63-MAPK) (MNK2) (Fragment) Length = 274 Score = 83.2 bits (204), Expect = 3e-16 Identities = 53/161 (32%), Positives = 86/161 (53%), Gaps = 10/161 (6%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFF--STTEKDELF----LNLVLEYVPETVHRVIRHYNKMNQRMP 162 ++R LDH N+V + + + ELF +V EY+ ET + + + Sbjct: 42 IIRRLDHDNIVKVYEVLGPKGSDLQGELFKFSVAYIVQEYM-ETDLACLLEQGTLTEE-- 98 Query: 163 LIYVKLYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPN 342 + KL+ YQ+ L YIH + V HRD+KP N+ ++ LKI DFG A++ + + Sbjct: 99 --HAKLFMYQLLRGLKYIH-SANVLHRDLKPANIFISTEDLVLKIGDFGLARIADQHYSH 155 Query: 343 ISYIC----SRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 Y+ +++YR+P L+ YT AID+W+AGC+LAE+ Sbjct: 156 KGYLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCILAEM 196
>CDK8_DROME (Q9VT57) Cell division protein kinase 8 (EC 2.7.11.22) (EC| 2.7.11.23) (DmCdk8) Length = 454 Score = 83.2 bits (204), Expect = 3e-16 Identities = 55/163 (33%), Positives = 87/163 (53%), Gaps = 12/163 (7%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYN-----KMNQRMPL 165 ++R L H NV++L F S ++ L+++Y + +I+ + K +P Sbjct: 69 LLRELKHQNVITLIRVFLSHNDRKVF---LLIDYAEHDLWHIIKFHRAAKATKKQVVVPR 125 Query: 166 IYVKLYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQ---LKICDFGSAKVL---V 327 VK YQI + Y+H V HRD+KP N+LV ++ +KI D G A++ + Sbjct: 126 GMVKSLLYQILDGIHYLHSN-WVLHRDLKPANILVMGDGNERGRVKIADMGFARLFNAPL 184 Query: 328 KGEPNIS-YICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 K ++ + + +YRAPEL+ GA YT AIDIW+ GC+ AEL Sbjct: 185 KPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAEL 227
>KKQ1_YEAST (P36005) Probable serine/threonine-protein kinase YKL161C (EC| 2.7.11.1) Length = 433 Score = 83.2 bits (204), Expect = 3e-16 Identities = 66/166 (39%), Positives = 88/166 (53%), Gaps = 15/166 (9%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELF-----LNLVLEYVPETVHRVIRHYNKMNQRMPL 165 + L HPN+V L F T D +F LN V Y E + + + QR+ Sbjct: 76 LRHLRGHPNIVWL----FDT---DIVFYPNGALNGVYLY-EELMECDLSQIIRSEQRLED 127 Query: 166 IYVKLYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSA-------KV- 321 + + + YQI AL YIH + V H D+KP+NLLVN QLKIC+FG + KV Sbjct: 128 AHFQSFIYQILCALKYIH-SANVLHCDLKPKNLLVNSDC-QLKICNFGLSCSYSENHKVN 185 Query: 322 --LVKGEPNISYICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 +KG YI S +Y+APE++ E T A+DIWS GC+LAEL Sbjct: 186 DGFIKG-----YITSIWYKAPEILLNYQECTKAVDIWSTGCILAEL 226
>MK04_MOUSE (Q6P5G0) Mitogen-activated protein kinase 4 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 4) (ERK-4) Length = 583 Score = 83.2 bits (204), Expect = 3e-16 Identities = 53/161 (32%), Positives = 87/161 (54%), Gaps = 10/161 (6%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFF--STTEKDELF----LNLVLEYVPETVHRVIRHYNKMNQRMP 162 ++R LDH N+V + + + ELF +V EY+ ET + + + Sbjct: 68 IIRRLDHDNIVKVYEVLGPKGSDLQGELFKFSVAYIVQEYM-ETDLACLLEQGTLTED-- 124 Query: 163 LIYVKLYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPN 342 + KL+ YQ+ L YIH + V HRD+KP N+ ++ LKI DFG A+++ + + Sbjct: 125 --HAKLFMYQLLRGLKYIH-SANVLHRDLKPANIFISTEDLVLKIGDFGLARIVDQHYSH 181 Query: 343 ISYIC----SRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 Y+ +++YR+P L+ YT AID+W+AGC+LAE+ Sbjct: 182 KGYLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCILAEM 222
>CDC2_CARAU (P51958) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 302 Score = 82.8 bits (203), Expect = 4e-16 Identities = 54/154 (35%), Positives = 84/154 (54%), Gaps = 3/154 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +++ L HPNVV L ++ L LV E++ + + + Q M + VK Sbjct: 54 LLKELQHPNVVRLLDVLMQESK-----LYLVFEFLSMDLKKYLDSIPS-GQFMDPMLVKS 107 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY--- 351 Y YQI + + H V HRD+KPQNLL++ + +K+ DFG A+ G P Y Sbjct: 108 YLYQILEGILFCHCR-RVLHRDLKPQNLLID-NKGVIKLADFGLARAF--GVPVRVYTHE 163 Query: 352 ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + + +YRAPE++ GA+ Y+T +D+WS G + AEL Sbjct: 164 VVTLWYRAPEVLLGASRYSTPVDVWSIGTIFAEL 197
>JNK_DROME (P92208) Stress-activated protein kinase JNK (EC 2.7.11.24) (dJNK)| (Protein basket) Length = 372 Score = 82.8 bits (203), Expect = 4e-16 Identities = 51/152 (33%), Positives = 85/152 (55%), Gaps = 1/152 (0%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELF-LNLVLEYVPETVHRVIRHYNKMNQRMPLIYVK 177 +M+L++H N++ L + F +E + LV+E + + +VI+ + + RM + Sbjct: 74 LMKLVNHKNIIGLLNAFTPQRNLEEFQDVYLVMELMDANLCQVIQ-MDLDHDRMSYLL-- 130 Query: 178 LYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYIC 357 YQ+ + ++H + G+ HRD+KP N++V LKI DFG A+ Y+ Sbjct: 131 ---YQMLCGIKHLH-SAGIIHRDLKPSNIVVKADC-TLKILDFGLARTAGTTFMMTPYVV 185 Query: 358 SRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 +RYYRAPE+I G YT +DIWS GC++ E+ Sbjct: 186 TRYYRAPEVILGMG-YTENVDIWSVGCIMGEM 216
>PRP4_SCHPO (Q07538) Serine/threonine-protein kinase prp4 (EC 2.7.11.1)| Length = 477 Score = 82.8 bits (203), Expect = 4e-16 Identities = 50/124 (40%), Positives = 72/124 (58%) Frame = +1 Query: 82 LNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKLYSYQICXALAYIHRTVGVCHRDIKPQN 261 L +V E + + +++ + + N + + V+LY+YQ+ AL + + V H DIKP N Sbjct: 234 LCMVFEMLSLNLRDILKKFGR-NVGLSIKAVRLYAYQMFMALDLL-KQCNVIHSDIKPDN 291 Query: 262 LLVNPHTHQLKICDFGSAKVLVKGEPNISYICSRYYRAPELIFGATEYTTAIDIWSAGCV 441 +LVN + LKICD GSA + E Y+ SR+YRAPE+I G Y+ ID WS GC Sbjct: 292 MLVNEKRNILKICDLGSASDASENEIT-PYLVSRFYRAPEIILG-FPYSCPIDTWSVGCS 349 Query: 442 LAEL 453 L EL Sbjct: 350 LYEL 353
>CCRK_HUMAN (Q8IZL9) Cell cycle-related kinase (EC 2.7.11.22)| (Cyclin-kinase-activating kinase p42) (CDK-activating kinase p42) (CAK-kinase p42) Length = 346 Score = 82.8 bits (203), Expect = 4e-16 Identities = 44/124 (35%), Positives = 70/124 (56%), Gaps = 2/124 (1%) Frame = +1 Query: 88 LVLEYVPETVHRVIRHYNKMNQRMPLIYVKLYSYQICXALAYIHRTVGVCHRDIKPQNLL 267 L E++ + V+RH + + VK Y + +A+ H + HRD+KP NLL Sbjct: 79 LAFEFMLSDLAEVVRHAQRP---LAQAQVKSYLQMLLKGVAFCHAN-NIVHRDLKPANLL 134 Query: 268 VNPHTHQLKICDFGSAKVLVKGEPNI--SYICSRYYRAPELIFGATEYTTAIDIWSAGCV 441 ++ + QLKI DFG A+V + + +R+YRAPEL++GA +Y +D+WS GC+ Sbjct: 135 ISA-SGQLKIADFGLARVFSPDGSRLYTHQVATRWYRAPELLYGARQYDQGVDLWSVGCI 193 Query: 442 LAEL 453 + EL Sbjct: 194 MGEL 197
>MK10_RAT (P49187) Mitogen-activated protein kinase 10 (EC 2.7.11.24)| (Stress-activated protein kinase JNK3) (c-Jun N-terminal kinase 3) (SAPK-beta) (p54-beta) Length = 464 Score = 82.8 bits (203), Expect = 4e-16 Identities = 51/152 (33%), Positives = 85/152 (55%), Gaps = 1/152 (0%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELF-LNLVLEYVPETVHRVIRHYNKMNQRMPLIYVK 177 +M+ ++H N++SL + F +E + LV+E + + +VI+ ++RM + Sbjct: 114 LMKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQ-MELDHERMSYLL-- 170 Query: 178 LYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYIC 357 YQ+ A+ ++H + G+ HRD+KP N++V LKI DFG A+ Y+ Sbjct: 171 ---YQMLSAIKHLH-SAGIIHRDLKPSNIVVKSDC-TLKILDFGLARTAGTSFMMTPYVV 225 Query: 358 SRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 +RYYRAPE+I G Y +DIWS GC++ E+ Sbjct: 226 TRYYRAPEVILG-MGYKENVDIWSVGCIMGEM 256
>CDC2_ORYLU (Q9DG98) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 82.8 bits (203), Expect = 4e-16 Identities = 53/154 (34%), Positives = 83/154 (53%), Gaps = 3/154 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +++ L HPNVV L + L L+ E++ + + + Q M + VK Sbjct: 54 LLQELKHPNVVRLLDVLMQESR-----LYLIFEFLSMDLKKYLDSIPS-GQYMDPMLVKS 107 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY--- 351 Y YQI + + HR V HRD+KPQNLL++ + +K+ DFG A+ G P Y Sbjct: 108 YLYQILEGIYFCHRR-RVLHRDLKPQNLLID-NKGVIKLADFGLARAF--GVPVRVYTHE 163 Query: 352 ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + + +YRAPE++ G+ Y+T +D+WS G + AEL Sbjct: 164 VVTLWYRAPEVLLGSPRYSTPVDVWSTGTIFAEL 197
>CDC2_ORYLA (Q9DGD3) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 82.8 bits (203), Expect = 4e-16 Identities = 53/154 (34%), Positives = 83/154 (53%), Gaps = 3/154 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +++ L HPNVV L + L L+ E++ + + + Q M + VK Sbjct: 54 LLQELKHPNVVRLLDVLMQESR-----LYLIFEFLSMDLKKYLDSIPS-GQYMDPMLVKS 107 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY--- 351 Y YQI + + HR V HRD+KPQNLL++ + +K+ DFG A+ G P Y Sbjct: 108 YLYQILEGIYFCHRR-RVLHRDLKPQNLLID-NKGVIKLADFGLARAF--GVPVRVYTHE 163 Query: 352 ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + + +YRAPE++ G+ Y+T +D+WS G + AEL Sbjct: 164 VVTLWYRAPEVLLGSPRYSTPVDVWSTGTIFAEL 197
>CDC2_ORYJA (Q9DGA2) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 82.8 bits (203), Expect = 4e-16 Identities = 53/154 (34%), Positives = 83/154 (53%), Gaps = 3/154 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +++ L HPNVV L + L L+ E++ + + + Q M + VK Sbjct: 54 LLQELKHPNVVRLLDVLMQESR-----LYLIFEFLSMDLKKYLDSIPS-GQYMDPMLVKS 107 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY--- 351 Y YQI + + HR V HRD+KPQNLL++ + +K+ DFG A+ G P Y Sbjct: 108 YLYQILEGIYFCHRR-RVLHRDLKPQNLLID-NKGVIKLADFGLARAF--GVPVRVYTHE 163 Query: 352 ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + + +YRAPE++ G+ Y+T +D+WS G + AEL Sbjct: 164 VVTLWYRAPEVLLGSPRYSTPVDVWSTGTIFAEL 197
>CDC2H_PLAKH (O96821) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 288 Score = 82.4 bits (202), Expect = 5e-16 Identities = 51/154 (33%), Positives = 85/154 (55%), Gaps = 3/154 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +++ L H N+V L + L LV E++ + + +++ + + + + K Sbjct: 53 ILKELKHSNIVKLYDVIHTKKR-----LILVFEHLDQDLKKLL---DVCDGGLESVTAKS 104 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY--- 351 + Q+ +AY H V HRD+KPQNLL+N +LKI DFG A+ G P Y Sbjct: 105 FLLQLLSGIAYCHEH-RVLHRDLKPQNLLIN-REGELKIADFGLARAF--GIPVRKYTHE 160 Query: 352 ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + + +YRAP+++ G+ +Y+T IDIWS GC+ AE+ Sbjct: 161 VVTLWYRAPDILMGSKKYSTPIDIWSVGCIFAEM 194
>CDC2H_PLACH (Q4Y4B1) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 288 Score = 82.4 bits (202), Expect = 5e-16 Identities = 52/154 (33%), Positives = 85/154 (55%), Gaps = 3/154 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +++ L H N+V L + L LV E++ + + ++I + + + + K Sbjct: 53 ILKELRHSNIVKLYDVIHAKKR-----LILVFEHLDQDLKKLI---DVCDGGLESVTAKS 104 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY--- 351 + Q+ +AY H V HRD+KPQNLL+N +LKI DFG A+ G P Y Sbjct: 105 FLLQLLNGIAYCHEH-RVLHRDLKPQNLLIN-REGELKIADFGLARAF--GIPARRYTHE 160 Query: 352 ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + + +YRAP+++ G+ +Y+T IDIWS GC+ AE+ Sbjct: 161 VVTLWYRAPDILMGSKKYSTPIDIWSVGCIFAEM 194
>CDC2H_PLABA (Q4Z6R1) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 288 Score = 82.4 bits (202), Expect = 5e-16 Identities = 52/154 (33%), Positives = 85/154 (55%), Gaps = 3/154 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +++ L H N+V L + L LV E++ + + ++I + + + + K Sbjct: 53 ILKELRHSNIVKLYDVIHAKKR-----LILVFEHLDQDLKKLI---DVCDGGLESVTAKS 104 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY--- 351 + Q+ +AY H V HRD+KPQNLL+N +LKI DFG A+ G P Y Sbjct: 105 FLLQLLNGIAYCHEH-RVLHRDLKPQNLLIN-REGELKIADFGLARAF--GIPARRYTHE 160 Query: 352 ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + + +YRAP+++ G+ +Y+T IDIWS GC+ AE+ Sbjct: 161 VVTLWYRAPDILMGSKKYSTPIDIWSVGCIFAEM 194
>MK14B_CYPCA (Q9I958) Mitogen-activated protein kinase 14b (EC 2.7.11.24)| (Mitogen-activated protein kinase p38b) (MAP kinase p38b) (cp38b) Length = 361 Score = 82.4 bits (202), Expect = 5e-16 Identities = 50/154 (32%), Positives = 84/154 (54%), Gaps = 3/154 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTT---EKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIY 171 +++ + H NV+ L F T ++++L V + ++ +++ Q++ + Sbjct: 75 LLKHMKHENVIGLLDAFSPATCLAGFNDVYL--VTHLMGADLNNIVKC-----QKLTDDH 127 Query: 172 VKLYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY 351 V+ YQI L YIH + + HRD+KP NL VN +LKI DFG A++ + Y Sbjct: 128 VQFLIYQILRGLKYIH-SADIIHRDLKPSNLAVNEDC-ELKILDFGLARLT--DDEMTGY 183 Query: 352 ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + +R+YRAPE++ Y +DIWS GC++AEL Sbjct: 184 VATRWYRAPEIMLNWMHYNMTVDIWSVGCIMAEL 217
>CDC2H_PLAYO (Q7RM49) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 289 Score = 82.4 bits (202), Expect = 5e-16 Identities = 52/154 (33%), Positives = 85/154 (55%), Gaps = 3/154 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +++ L H N+V L + L LV E++ + + ++I + + + + K Sbjct: 54 ILKELRHSNIVKLYDVIHAKKR-----LILVFEHLDQDLKKLI---DVCDGGLESVTAKS 105 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY--- 351 + Q+ +AY H V HRD+KPQNLL+N +LKI DFG A+ G P Y Sbjct: 106 FLLQLLNGIAYCHEH-RVLHRDLKPQNLLIN-REGELKIADFGLARAF--GIPARRYTHE 161 Query: 352 ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + + +YRAP+++ G+ +Y+T IDIWS GC+ AE+ Sbjct: 162 VVTLWYRAPDILMGSKKYSTPIDIWSVGCIFAEM 195
>CDC2C_DROME (P23573) Cell division control protein 2 cognate (EC 2.7.11.22) (EC| 2.7.11.23) Length = 314 Score = 82.4 bits (202), Expect = 5e-16 Identities = 51/154 (33%), Positives = 84/154 (54%), Gaps = 3/154 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +++ L HPNVV L S L ++ EY+ + +++ +K +K Sbjct: 58 LLKNLKHPNVVQLFDVVISGNN-----LYMIFEYLNMDLKKLM---DKKKDVFTPQLIKS 109 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY--- 351 Y +QI A+ + H T + HRD+KPQNLLV+ ++K+ DFG A+ P +Y Sbjct: 110 YMHQILDAVGFCH-TNRILHRDLKPQNLLVDT-AGKIKLADFGLARAF--NVPMRAYTHE 165 Query: 352 ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + + +YRAPE++ G Y+T +DIWS GC+ +E+ Sbjct: 166 VVTLWYRAPEILLGTKFYSTGVDIWSLGCIFSEM 199
>YP62_CAEEL (Q09437) Putative serine/threonine-protein kinase B0495.2 (EC| 2.7.11.1) Length = 719 Score = 82.4 bits (202), Expect = 5e-16 Identities = 46/153 (30%), Positives = 89/153 (58%), Gaps = 3/153 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +++ +HPN+V++K + D++++ +E+V + ++ ++ N+R + K Sbjct: 407 LLKAGNHPNIVNVKEILLGSN-MDKIYM--AMEFVEHDMKSLLDTMSRRNKRFSIGEQKT 463 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPN---ISY 351 Q+ + ++H+ + + HRD+K NLL++ H LKI DFG A+ G+P S Sbjct: 464 LLQQLLSGIEHMHK-LWILHRDLKTSNLLMS-HKGILKIADFGLAREY--GDPLKKFTSI 519 Query: 352 ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAE 450 + + +YR+PEL+ G Y+T +D+WS GC++AE Sbjct: 520 VVTLWYRSPELLLGTRLYSTPVDMWSVGCIMAE 552
>CDC2_DICDI (P34112) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) Length = 296 Score = 82.4 bits (202), Expect = 5e-16 Identities = 52/155 (33%), Positives = 84/155 (54%), Gaps = 4/155 (2%) Frame = +1 Query: 1 MMRLLDHPNVVSL---KHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIY 171 +++ + HPNVVSL HC + L LV EY+ + + + + + ++ Sbjct: 58 LLKEVPHPNVVSLFDVLHC--------QNRLYLVFEYLDQDLKKYMDSVPALCPQL---- 105 Query: 172 VKLYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAK-VLVKGEPNIS 348 +K Y YQ+ LAY H + HRD+KPQNLL++ LK+ DFG A+ V + Sbjct: 106 IKSYLYQLLKGLAYSHGH-RILHRDLKPQNLLID-RQGALKLADFGLARAVSIPVRVYTH 163 Query: 349 YICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 I + +YRAPE++ G+ Y+ +D+WS GC+ E+ Sbjct: 164 EIVTLWYRAPEVLLGSKSYSVPVDMWSVGCIFGEM 198
>MK08_BRARE (Q9DGD9) Mitogen-activated protein kinase 8 (EC 2.7.11.24)| (Stress-activated protein kinase JNK1) (c-Jun N-terminal kinase 1) Length = 384 Score = 82.0 bits (201), Expect = 6e-16 Identities = 51/154 (33%), Positives = 84/154 (54%), Gaps = 3/154 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELF-LNLVLEYVPETVHRVIRHYNKMNQRMPLIYVK 177 +M+ ++H N++ L + F +E + LV+E + + +VI+ M L + + Sbjct: 76 LMKCVNHKNIIGLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQ--------MELDHER 127 Query: 178 L--YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY 351 L YQ+ + ++H G+ HRD+KP N++V LKI DFG A+ G Y Sbjct: 128 LSYLLYQMLCGIKHLH-AAGIIHRDLKPSNIVVKSDC-TLKILDFGLARTAATGLLMTPY 185 Query: 352 ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + +RYYRAPE+I G Y +D+WS GC++AE+ Sbjct: 186 VVTRYYRAPEVILG-MGYQANVDVWSIGCIMAEM 218
>CDK7_CARAU (P51953) Cell division protein kinase 7 (EC 2.7.11.22) (EC| 2.7.11.23) (40 kDa protein kinase) (P40 MO15) (CDC2/CDK2,4-activating kinase) Length = 344 Score = 82.0 bits (201), Expect = 6e-16 Identities = 54/155 (34%), Positives = 80/155 (51%), Gaps = 4/155 (2%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDEL-FLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVK 177 +++ L HPN++ L F + L F+ LE + + V+ N +K Sbjct: 65 LLQELSHPNIIGLLDAFGHKSNISLLCFMETDLEVIIKDTSLVLTPAN----------IK 114 Query: 178 LYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY-- 351 Y L Y+H + HRD+KP NLL++ + LK+ DFG AK G PN Y Sbjct: 115 AYILMSLQGLEYMHNH-WILHRDLKPNNLLLDENG-VLKLADFGLAKAF--GSPNRVYTH 170 Query: 352 -ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + +R+YRAPEL+FGA Y +D+W+ G +LAEL Sbjct: 171 QVVTRWYRAPELLFGARMYGVGVDMWAVGSILAEL 205
>CCRK_RAT (Q4KM34) Cell cycle-related kinase (EC 2.7.11.22)| Length = 346 Score = 82.0 bits (201), Expect = 6e-16 Identities = 44/124 (35%), Positives = 70/124 (56%), Gaps = 2/124 (1%) Frame = +1 Query: 88 LVLEYVPETVHRVIRHYNKMNQRMPLIYVKLYSYQICXALAYIHRTVGVCHRDIKPQNLL 267 L E++ + V+RH + + VK Y + +A+ H + HRD+KP NLL Sbjct: 79 LAFEFMLSDLAEVVRHAQRP---LAPAQVKSYLQMLLKGVAFCHAN-NIVHRDLKPANLL 134 Query: 268 VNPHTHQLKICDFGSAKVLVK--GEPNISYICSRYYRAPELIFGATEYTTAIDIWSAGCV 441 ++ + QLKI DFG A+V G + +R+YRAPEL++GA +Y +D+W+ GC+ Sbjct: 135 ISA-SGQLKIADFGLARVFSPDGGRLYTHQVATRWYRAPELLYGARQYDQGVDLWAVGCI 193 Query: 442 LAEL 453 + EL Sbjct: 194 MGEL 197
>CCRK_MOUSE (Q9JHU3) Cell cycle-related kinase (EC 2.7.11.22)| (Cyclin-kinase-activating kinase p42) (CDK-activating kinase p42) (CAK-kinase p42) (CDK-related protein kinase PNQLARE) Length = 346 Score = 82.0 bits (201), Expect = 6e-16 Identities = 44/124 (35%), Positives = 70/124 (56%), Gaps = 2/124 (1%) Frame = +1 Query: 88 LVLEYVPETVHRVIRHYNKMNQRMPLIYVKLYSYQICXALAYIHRTVGVCHRDIKPQNLL 267 L E++ + V+RH + + VK Y + +A+ H + HRD+KP NLL Sbjct: 79 LAFEFMLSDLAEVVRHAQRP---LAPAQVKSYLQMLLKGVAFCHAN-NIVHRDLKPANLL 134 Query: 268 VNPHTHQLKICDFGSAKVLVK--GEPNISYICSRYYRAPELIFGATEYTTAIDIWSAGCV 441 ++ + QLKI DFG A+V G + +R+YRAPEL++GA +Y +D+W+ GC+ Sbjct: 135 ISA-SGQLKIADFGLARVFSPDGGRLYTHQVATRWYRAPELLYGARQYDQGVDLWAVGCI 193 Query: 442 LAEL 453 + EL Sbjct: 194 MGEL 197
>SMK1_YEAST (P41808) Sporulation-specific mitogen-activated protein kinase SMK1| (EC 2.7.11.24) (MAP kinase SMK1) Length = 388 Score = 81.6 bits (200), Expect = 8e-16 Identities = 44/103 (42%), Positives = 65/103 (63%), Gaps = 9/103 (8%) Frame = +1 Query: 169 YVKLYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKG----- 333 ++K + YQI L YIH + V HRD+KP N+L + LKICDFG A+ + G Sbjct: 142 HIKYFLYQILCGLKYIH-SADVIHRDLKPGNILCTLNGC-LKICDFGLARGIHAGFFKCH 199 Query: 334 ---EPNIS-YICSRYYRAPELIFGATEYTTAIDIWSAGCVLAE 450 +P+I+ Y+ +R+YRAPEL+ Y+ ++DIW+ GC+LAE Sbjct: 200 STVQPHITNYVATRWYRAPELLLSNQPYSKSVDIWAVGCILAE 242
>MK08B_CYPCA (O42099) Mitogen-activated protein kinase 8B (EC 2.7.11.24)| (Stress-activated protein kinase JNKb) (c-Jun N-terminal kinase B) Length = 427 Score = 81.6 bits (200), Expect = 8e-16 Identities = 51/154 (33%), Positives = 84/154 (54%), Gaps = 3/154 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELF-LNLVLEYVPETVHRVIRHYNKMNQRMPLIYVK 177 +M+ ++H N++ L + F +E + LV+E + + +VI+ M L + + Sbjct: 76 LMKCVNHKNIIGLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQ--------MELDHER 127 Query: 178 L--YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY 351 L YQ+ ++H + G+ HRD+KP N++V LKI DFG A+ G Y Sbjct: 128 LSYLLYQMLCGTKHLH-SAGIIHRDLKPSNIVVKSDC-TLKILDFGLARTAATGLLMTPY 185 Query: 352 ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + +RYYRAPE+I G Y +D+WS GC++AE+ Sbjct: 186 VVTRYYRAPEVILG-MGYQANVDVWSVGCIMAEM 218
>CD2L5_MOUSE (Q69ZA1) Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22)| (CDC2-related protein kinase 5) Length = 1511 Score = 81.6 bits (200), Expect = 8e-16 Identities = 51/162 (31%), Positives = 85/162 (52%), Gaps = 11/162 (6%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTE-----KDELFLNLVLEYVPETVHRVIR----HYNKMNQ 153 ++R L H +++++K + KD+ LV EY+ + ++ H+N+ Sbjct: 755 ILRQLTHQSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNEN-- 812 Query: 154 RMPLIYVKLYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKG 333 ++K + Q+ L Y H+ HRDIK N+L+N + Q+K+ DFG A++ Sbjct: 813 -----HIKSFMRQLMEGLDYCHKK-NFLHRDIKCSNILLN-NRGQIKLADFGLARLYSSE 865 Query: 334 E--PNISYICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 E P + + + +YR PEL+ G YT AID+WS GC+L EL Sbjct: 866 ESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGEL 907
>CD2L5_HUMAN (Q14004) Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22)| (CDC2-related protein kinase 5) (Cholinesterase-related cell division controller) Length = 1512 Score = 81.6 bits (200), Expect = 8e-16 Identities = 51/162 (31%), Positives = 85/162 (52%), Gaps = 11/162 (6%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTE-----KDELFLNLVLEYVPETVHRVIR----HYNKMNQ 153 ++R L H +++++K + KD+ LV EY+ + ++ H+N+ Sbjct: 755 ILRQLTHQSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNEN-- 812 Query: 154 RMPLIYVKLYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKG 333 ++K + Q+ L Y H+ HRDIK N+L+N + Q+K+ DFG A++ Sbjct: 813 -----HIKSFMRQLMEGLDYCHKK-NFLHRDIKCSNILLN-NRGQIKLADFGLARLYSSE 865 Query: 334 E--PNISYICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 E P + + + +YR PEL+ G YT AID+WS GC+L EL Sbjct: 866 ESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGEL 907
>CDC2_ORYCU (Q9DGA5) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 81.6 bits (200), Expect = 8e-16 Identities = 52/154 (33%), Positives = 83/154 (53%), Gaps = 3/154 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +++ L HPNVV L + L L+ E++ + + + Q M + VK Sbjct: 54 LLQELKHPNVVRLLDVLMQESR-----LYLIFEFLSMDLKKYLDSIPS-GQYMDPMLVKS 107 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY--- 351 Y YQI + + HR V HRD+KPQNLL++ + +K+ DFG ++ G P Y Sbjct: 108 YLYQILEGIYFCHRR-RVLHRDLKPQNLLID-NKGVIKLADFGLSRAF--GVPVRVYTHE 163 Query: 352 ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + + +YRAPE++ G+ Y+T +D+WS G + AEL Sbjct: 164 VVTLWYRAPEVLLGSPRYSTPVDVWSTGTIFAEL 197
>BUR1_YEAST (P23293) Serine/threonine-protein kinase BUR1 (EC 2.7.11.22) (EC| 2.7.11.23) (Suppressor of GPA1-Vall50 mutation protein 1) (Bypass UAS requirement protein 1) Length = 657 Score = 81.3 bits (199), Expect = 1e-15 Identities = 54/171 (31%), Positives = 84/171 (49%), Gaps = 21/171 (12%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFF--------STTEKDELFLNLVLEYVPETVHRVIRHYNKMNQR 156 +++ L+H N++ L + + + ++L Y+ + V+ H ++N Sbjct: 110 ILKRLNHKNIIKLIEMVYDHSPDITNAASSNLHKSFYMILPYMVADLSGVL-HNPRINLE 168 Query: 157 MPLIYVKLYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGE 336 M +K QI L YIH HRDIK N+L++ H LK+ DFG A++ Sbjct: 169 M--CDIKNMMLQILEGLNYIH-CAKFMHRDIKTANILID-HNGVLKLADFGLARLYYGCP 224 Query: 337 PNISY-------------ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAE 450 PN+ Y + +R+YRAPEL+ G +YTTA+DIW GCV AE Sbjct: 225 PNLKYPGGAGSGAKYTSVVVTRWYRAPELVLGDKQYTTAVDIWGVGCVFAE 275
>CDC2H_PLAVI (Q9XZD6) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (Pvcrk2) Length = 288 Score = 81.3 bits (199), Expect = 1e-15 Identities = 50/154 (32%), Positives = 85/154 (55%), Gaps = 3/154 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +++ L H N+V L + L LV E++ + + +++ + + + + K Sbjct: 53 ILKELKHSNIVKLYDVIHTKKR-----LILVFEHLDQDLKKLL---DVCDGGLESVTAKS 104 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY--- 351 + Q+ +AY H V HRD+KPQNLL+N +LKI DFG A+ G P Y Sbjct: 105 FLLQLLSGIAYCHEH-RVLHRDLKPQNLLIN-REGELKIADFGLARAF--GIPVRKYTHE 160 Query: 352 ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + + +YRAP+++ G+ +Y+T ID+WS GC+ AE+ Sbjct: 161 VVTLWYRAPDILMGSKKYSTPIDMWSVGCIFAEM 194
>CDC2H_PLAFK (Q07785) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (PfPK5) Length = 288 Score = 81.3 bits (199), Expect = 1e-15 Identities = 51/154 (33%), Positives = 84/154 (54%), Gaps = 3/154 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +++ L H N+V L + L LV E++ + + +++ + + + K Sbjct: 53 ILKELKHSNIVKLYDVIHTKKR-----LVLVFEHLDQDLKKLL---DVCEGGLESVTAKS 104 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY--- 351 + Q+ +AY H V HRD+KPQNLL+N +LKI DFG A+ G P Y Sbjct: 105 FLLQLLNGIAYCHDR-RVLHRDLKPQNLLIN-REGELKIADFGLARAF--GIPVRKYTHE 160 Query: 352 ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + + +YRAP+++ G+ +Y+T IDIWS GC+ AE+ Sbjct: 161 VVTLWYRAPDVLMGSKKYSTTIDIWSVGCIFAEM 194
>CDC2H_PLAF7 (P61075) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 288 Score = 81.3 bits (199), Expect = 1e-15 Identities = 51/154 (33%), Positives = 84/154 (54%), Gaps = 3/154 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +++ L H N+V L + L LV E++ + + +++ + + + K Sbjct: 53 ILKELKHSNIVKLYDVIHTKKR-----LVLVFEHLDQDLKKLL---DVCEGGLESVTAKS 104 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY--- 351 + Q+ +AY H V HRD+KPQNLL+N +LKI DFG A+ G P Y Sbjct: 105 FLLQLLNGIAYCHDR-RVLHRDLKPQNLLIN-REGELKIADFGLARAF--GIPVRKYTHE 160 Query: 352 ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + + +YRAP+++ G+ +Y+T IDIWS GC+ AE+ Sbjct: 161 VVTLWYRAPDVLMGSKKYSTTIDIWSVGCIFAEM 194
>GIN4_YEAST (Q12263) Serine/threonine-protein kinase GIN4 (EC 2.7.11.1)| Length = 1142 Score = 81.3 bits (199), Expect = 1e-15 Identities = 55/160 (34%), Positives = 83/160 (51%), Gaps = 9/160 (5%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTT---------EKDELFLNLVLEYVPETVHRVIRHYNKMNQ 153 +M+LL+HPNV+ L + + T EK ELF NL++E P H IR + Sbjct: 84 IMKLLNHPNVLRLYDVWETNTDLYLVLEYAEKGELF-NLLVERGPLPEHEAIRFFR---- 138 Query: 154 RMPLIYVKLYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKG 333 QI ++Y H +G+ HRD+KP+NLL++ H + +KI DFG A + +G Sbjct: 139 ------------QIIIGVSYCH-ALGIVHRDLKPENLLLD-HKYNIKIADFGMAALETEG 184 Query: 334 EPNISYICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + + S +Y APE++ G A D+WS G +L L Sbjct: 185 KLLETSCGSPHYAAPEIVSGIPYQGFASDVWSCGVILFAL 224
>MK13_HUMAN (O15264) Mitogen-activated protein kinase 13 (EC 2.7.11.24)| (Stress-activated protein kinase 4) (Mitogen-activated protein kinase p38 delta) (MAP kinase p38 delta) Length = 365 Score = 81.3 bits (199), Expect = 1e-15 Identities = 49/152 (32%), Positives = 77/152 (50%), Gaps = 1/152 (0%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELF-LNLVLEYVPETVHRVIRHYNKMNQRMPLIYVK 177 +++ + H NV+ L F + + LV+ ++ + ++ M ++ Sbjct: 75 LLKHMQHENVIGLLDVFTPASSLRNFYDFYLVMPFMQTDLQKI------MGMEFSEEKIQ 128 Query: 178 LYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYIC 357 YQ+ L YIH + GV HRD+KP NL VN +LKI DFG A+ Y+ Sbjct: 129 YLVYQMLKGLKYIH-SAGVVHRDLKPGNLAVNEDC-ELKILDFGLARHA--DAEMTGYVV 184 Query: 358 SRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 +R+YRAPE+I Y +DIWS GC++AE+ Sbjct: 185 TRWYRAPEVILSWMHYNQTVDIWSVGCIMAEM 216
>CHK2_CAEEL (Q9U1Y5) Serine/threonine-protein kinase chk-2 (EC 2.7.11.1)| (Ce-cds-1) (Ce-chk-2) Length = 476 Score = 81.3 bits (199), Expect = 1e-15 Identities = 59/160 (36%), Positives = 88/160 (55%), Gaps = 12/160 (7%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVP--ETVHRVI-RHYNKMNQRMPLIY 171 +M+ L HPN+V++ + T K + +V+EYV E +V+ YN+M L Sbjct: 225 VMKKLSHPNIVAIYD--WITVAK---YSYMVIEYVGGGEFFSKVVDSKYNRMGLGESL-- 277 Query: 172 VKLYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQ--LKICDFGSAKVLVK----- 330 K +++Q+ A+ Y+H +VG+CHRDIKP+N+L + + LK+ DFG AK V Sbjct: 278 GKYFAFQLIDAILYLH-SVGICHRDIKPENILCSDKAERCILKLTDFGMAKNSVNRMKTR 336 Query: 331 -GEPNISYICSRYYRAPELIFG-ATEYTTAIDIWSAGCVL 444 G P+ Y APE++ EYT +DIWS GCVL Sbjct: 337 CGTPS--------YNAPEIVANEGVEYTPKVDIWSLGCVL 368
>CDC2_PONPY (Q5RCH1) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 81.3 bits (199), Expect = 1e-15 Identities = 52/154 (33%), Positives = 82/154 (53%), Gaps = 3/154 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +++ L HPN+VSL+ + L L+ E++ + + + Q M VK Sbjct: 54 LLKELRHPNIVSLQDVLMQDSR-----LYLIFEFLSMDLKKYLDSIPP-GQYMDSSLVKS 107 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY--- 351 Y YQI + + H V HRD+KPQNLL++ +K+ DFG A+ G P Y Sbjct: 108 YLYQILQGIVFCHSR-RVLHRDLKPQNLLIDDKG-TIKLADFGLARAF--GIPIRVYTHE 163 Query: 352 ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + + +YR+PE++ G+ Y+T +DIWS G + AEL Sbjct: 164 VVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAEL 197
>CDC2_HUMAN (P06493) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 81.3 bits (199), Expect = 1e-15 Identities = 52/154 (33%), Positives = 82/154 (53%), Gaps = 3/154 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +++ L HPN+VSL+ + L L+ E++ + + + Q M VK Sbjct: 54 LLKELRHPNIVSLQDVLMQDSR-----LYLIFEFLSMDLKKYLDSIPP-GQYMDSSLVKS 107 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY--- 351 Y YQI + + H V HRD+KPQNLL++ +K+ DFG A+ G P Y Sbjct: 108 YLYQILQGIVFCHSR-RVLHRDLKPQNLLIDDKG-TIKLADFGLARAF--GIPIRVYTHE 163 Query: 352 ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + + +YR+PE++ G+ Y+T +DIWS G + AEL Sbjct: 164 VVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAEL 197
>PRK1_SCHPO (O13958) Serine/threonine-protein kinase prk1 (EC 2.7.11.22)| (Suppressor of RNA polymerase B srb10) Length = 352 Score = 80.9 bits (198), Expect = 1e-15 Identities = 50/158 (31%), Positives = 87/158 (55%), Gaps = 7/158 (4%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQR-MPLIYVK 177 + R + H N+VSL KD +++V EY + ++I +++ R +P +K Sbjct: 64 LCREIQHENIVSLVQVLL----KDGT-ISMVFEYAEHDLLQIIHFHSRSRTRQIPPSILK 118 Query: 178 LYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYIC 357 +QI +AY+H + HRD+KP N+++ T ++KI D G +++ +P + + Sbjct: 119 SILWQIINGVAYLHEN-WIMHRDLKPANIMITA-TGKVKIGDLGLGRLI--RDPILPFYS 174 Query: 358 SR------YYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 S +YRAPEL+ GA +YT AID+W+ GC+ E+ Sbjct: 175 SDRVVVTIWYRAPELLLGAHDYTPAIDVWAIGCIYGEM 212
>CDC2_RAT (P39951) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 80.9 bits (198), Expect = 1e-15 Identities = 52/154 (33%), Positives = 82/154 (53%), Gaps = 3/154 (1%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 +++ L HPN+VSL+ + L L+ E++ + + + Q M VK Sbjct: 54 LLKELRHPNIVSLQDVLMQDSR-----LYLIFEFLSMDLKKYLDSIPP-GQFMDSSLVKS 107 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY--- 351 Y YQI + + H V HRD+KPQNLL++ +K+ DFG A+ G P Y Sbjct: 108 YLYQILQGIVFCHSR-RVLHRDLKPQNLLIDDKG-TIKLADFGLARAF--GIPIRVYTHE 163 Query: 352 ICSRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 + + +YR+PE++ G+ Y+T +DIWS G + AEL Sbjct: 164 VVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAEL 197
>MK08_XENLA (Q8QHK8) Mitogen-activated protein kinase 8 (EC 2.7.11.24)| (Stress-activated protein kinase JNK1) Length = 426 Score = 80.5 bits (197), Expect = 2e-15 Identities = 50/152 (32%), Positives = 83/152 (54%), Gaps = 1/152 (0%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELF-LNLVLEYVPETVHRVIRHYNKMNQRMPLIYVK 177 +M+ ++H N++ L + F +E L +V+E + + +VI+ ++RM + Sbjct: 76 LMKCVNHKNIIGLLNVFTPQKSLEEFQDLYIVMELMDANLCQVIQ-MELDHERMSYLL-- 132 Query: 178 LYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYIC 357 YQ+ + ++H + G+ HRD+KP N++V LKI DFG A+ Y+ Sbjct: 133 ---YQMLCGIKHLH-SAGIIHRDLKPSNIVVKSDC-TLKILDFGLARTAGTSFMMTPYVV 187 Query: 358 SRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 +RYYRAPE+I G Y +DIWS GC+L E+ Sbjct: 188 TRYYRAPEVILG-MGYKENVDIWSVGCILGEM 218
>CDC2C_ANTMA (Q38774) Cell division control protein 2 homolog C (EC 2.7.11.22)| (EC 2.7.11.23) Length = 305 Score = 80.5 bits (197), Expect = 2e-15 Identities = 48/145 (33%), Positives = 83/145 (57%), Gaps = 3/145 (2%) Frame = +1 Query: 28 VVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLI--YVKLYSYQICX 201 ++S++H + K L+L V EY+ + + I + K PL ++ + +Q+C Sbjct: 67 LLSVEHVDCAKNGKPLLYL--VFEYLDTDLKKFIDSHRKGPNPRPLPPQQIQSFLFQLCK 124 Query: 202 ALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY-ICSRYYRAP 378 +++ H GV HRD+KPQNLL++ LKI D G A+ + ++ I + YRAP Sbjct: 125 GVSHCHAH-GVLHRDLKPQNLLLDKDKGVLKIADLGLARAFTVPLKSYTHEIVTLSYRAP 183 Query: 379 ELIFGATEYTTAIDIWSAGCVLAEL 453 E++ G++ Y+TA+D+ S GC+ AE+ Sbjct: 184 EVLLGSSHYSTAVDMSSVGCIFAEM 208
>CDK6_MOUSE (Q64261) Cell division protein kinase 6 (EC 2.7.11.22)| (Serine/threonine-protein kinase PLSTIRE) (CRK2) Length = 326 Score = 80.5 bits (197), Expect = 2e-15 Identities = 51/151 (33%), Positives = 85/151 (56%), Gaps = 1/151 (0%) Frame = +1 Query: 4 MRLLDHPNVVSLKH-CFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 + +HPNVV L C S T++ E L LV E+V + + + + +P +K Sbjct: 68 LETFEHPNVVRLFDVCTVSRTDR-ETKLTLVFEHVDQDLTTYLDKVPEPG--VPTETIKD 124 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYICS 360 +Q+ L ++H + V HRD+KPQN+LV + Q+K+ DFG A++ S + + Sbjct: 125 MMFQLLRGLDFLH-SHRVVHRDLKPQNILVTS-SGQIKLADFGLARIYSFQMALTSVVVT 182 Query: 361 RYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 +YRAPE++ ++ Y T +D+WS GC+ AE+ Sbjct: 183 LWYRAPEVLLQSS-YATPVDLWSVGCIFAEM 212
>CDK6_HUMAN (Q00534) Cell division protein kinase 6 (EC 2.7.11.22)| (Serine/threonine-protein kinase PLSTIRE) Length = 326 Score = 80.5 bits (197), Expect = 2e-15 Identities = 51/151 (33%), Positives = 85/151 (56%), Gaps = 1/151 (0%) Frame = +1 Query: 4 MRLLDHPNVVSLKH-CFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKL 180 + +HPNVV L C S T++ E L LV E+V + + + + +P +K Sbjct: 68 LETFEHPNVVRLFDVCTVSRTDR-ETKLTLVFEHVDQDLTTYLDKVPEPG--VPTETIKD 124 Query: 181 YSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYICS 360 +Q+ L ++H + V HRD+KPQN+LV + Q+K+ DFG A++ S + + Sbjct: 125 MMFQLLRGLDFLH-SHRVVHRDLKPQNILVTS-SGQIKLADFGLARIYSFQMALTSVVVT 182 Query: 361 RYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 +YRAPE++ ++ Y T +D+WS GC+ AE+ Sbjct: 183 LWYRAPEVLLQSS-YATPVDLWSVGCIFAEM 212
>CDK4_XENLA (Q91727) Cell division protein kinase 4 (EC 2.7.11.22)| (Cyclin-dependent kinase 4) Length = 319 Score = 80.5 bits (197), Expect = 2e-15 Identities = 48/146 (32%), Positives = 76/146 (52%) Frame = +1 Query: 16 DHPNVVSLKHCFFSTTEKDELFLNLVLEYVPETVHRVIRHYNKMNQRMPLIYVKLYSYQI 195 DHPN+V L S E + LV E+V + + + +PL +K Q Sbjct: 67 DHPNIVKLMDVCASARTDRETKVTLVFEHVDQDLKTYLSKVPPPG--LPLETIKDLMKQF 124 Query: 196 CXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYICSRYYRA 375 L ++H + HRD+KP+N+LV Q+K+ DFG A++ + + +YRA Sbjct: 125 LSGLEFLHLNC-IVHRDLKPENILVTSGG-QVKLADFGLARIYSCQMALTPVVVTLWYRA 182 Query: 376 PELIFGATEYTTAIDIWSAGCVLAEL 453 PE++ +T Y T +D+WSAGC+ AE+ Sbjct: 183 PEVLLQST-YATPVDVWSAGCIFAEM 207
>CCRK_PONPY (Q5R7I7) Cell cycle-related kinase (EC 2.7.11.22)| Length = 346 Score = 80.5 bits (197), Expect = 2e-15 Identities = 42/124 (33%), Positives = 70/124 (56%), Gaps = 2/124 (1%) Frame = +1 Query: 88 LVLEYVPETVHRVIRHYNKMNQRMPLIYVKLYSYQICXALAYIHRTVGVCHRDIKPQNLL 267 L E++ + V+RH + + VK Y + +++ H + HRD+KP NLL Sbjct: 79 LAFEFMLSDLAEVVRHAQRP---LAQAQVKSYLQMLLKGVSFCHAN-NIVHRDLKPANLL 134 Query: 268 VNPHTHQLKICDFGSAKVLVKGEPNI--SYICSRYYRAPELIFGATEYTTAIDIWSAGCV 441 ++ + QLKI DFG A+V + + +R+YRAPEL++GA +Y +D+W+ GC+ Sbjct: 135 ISA-SGQLKIADFGLARVFSPDGSRLYTHQVATRWYRAPELLYGARQYDQGVDLWAVGCI 193 Query: 442 LAEL 453 + EL Sbjct: 194 MGEL 197
>MK10_MOUSE (Q61831) Mitogen-activated protein kinase 10 (EC 2.7.11.24)| (Stress-activated protein kinase JNK3) (c-Jun N-terminal kinase 3) (MAP kinase p49 3F12) Length = 464 Score = 80.5 bits (197), Expect = 2e-15 Identities = 50/152 (32%), Positives = 84/152 (55%), Gaps = 1/152 (0%) Frame = +1 Query: 1 MMRLLDHPNVVSLKHCFFSTTEKDELF-LNLVLEYVPETVHRVIRHYNKMNQRMPLIYVK 177 +M+ ++H N++SL + F +E + LV+E + + +VI+ ++RM + Sbjct: 114 LMKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQ-MELDHERMSYLL-- 170 Query: 178 LYSYQICXALAYIHRTVGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYIC 357 YQ+ + ++H + G+ HRD+KP N++V LKI DFG A+ Y+ Sbjct: 171 ---YQMLCGIKHLH-SAGIIHRDLKPSNIVVKSDC-TLKILDFGLARTAGTSFMMTPYVV 225 Query: 358 SRYYRAPELIFGATEYTTAIDIWSAGCVLAEL 453 +RYYRAPE+I G Y +DIWS GC++ E+ Sbjct: 226 TRYYRAPEVILG-MGYKENVDIWSVGCIMGEM 256 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 65,534,793 Number of Sequences: 219361 Number of extensions: 1302997 Number of successful extensions: 6280 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 4776 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4960 length of database: 80,573,946 effective HSP length: 102 effective length of database: 58,199,124 effective search space used: 2793557952 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
