ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | basd19o21 |
|---|---|
| Clone Library Name | barley_pub |
>ASPRX_ORYSA (P42211) Aspartic proteinase precursor (EC 3.4.23.-)| Length = 496 Score = 229 bits (585), Expect = 3e-60 Identities = 118/178 (66%), Positives = 137/178 (76%) Frame = +3 Query: 24 LGVTCLWILSCALLLGGACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHS 203 L TCLW LSCALLL A SDG LR+NL+KKRLDKE LTAAKLA+Q +LL++ Sbjct: 8 LVTTCLWALSCALLLH-ASSDGFLRVNLNKKRLDKEDLTAAKLAQQGNRLLKT------- 59 Query: 204 LGLSGDDIVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHH 383 G S D VPL +YL+TQY+G IG+G+PPQNFTVIFDTGSSNLWVPS+KCYFSIACYLH Sbjct: 60 -GSSDSDPVPLVDYLNTQYYGVIGLGSPPQNFTVIFDTGSSNLWVPSAKCYFSIACYLHS 118 Query: 384 XXXXXXXXXXXXNGETCTISYGSGSIAGFFSEDSVLVGELVVKNQKFIETTREASPTF 557 +GETC I+YGSG+I+GFFS+D+VLVG+LVVKNQKFIE TRE S TF Sbjct: 119 RYNSKKSSSYKADGETCKITYGSGAISGFFSKDNVLVGDLVVKNQKFIEATRETSVTF 176
>ASPR1_ORYSA (Q42456) Aspartic proteinase oryzasin-1 precursor (EC 3.4.23.-)| Length = 509 Score = 177 bits (448), Expect = 2e-44 Identities = 91/166 (54%), Positives = 114/166 (68%), Gaps = 1/166 (0%) Frame = +3 Query: 63 LLGGACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHSLGLSGD-DIVPLD 239 LL + ++GL+RI L K+ +D+ + AA+L+ +E G+ G G+ DIV L Sbjct: 19 LLPASAAEGLVRIALKKRPIDENSRVAARLSGEEGARRLGLRGANSLGGGGGEGDIVALK 78 Query: 240 NYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXXXXXXX 419 NY++ QYFGEIGVGTPPQ FTVIFDTGSSNLWVPS+KCYFSIAC+ H Sbjct: 79 NYMNAQYFGEIGVGTPPQKFTVIFDTGSSNLWVPSAKCYFSIACFFHSRYKSGQSSTYQK 138 Query: 420 NGETCTISYGSGSIAGFFSEDSVLVGELVVKNQKFIETTREASPTF 557 NG+ I YG+GSIAGFFSEDSV VG+LVVK+Q+FIE T+E TF Sbjct: 139 NGKPAAIQYGTGSIAGFFSEDSVTVGDLVVKDQEFIEATKEPGLTF 184
>ASPR_HORVU (P42210) Phytepsin precursor (EC 3.4.23.40) (Aspartic proteinase)| [Contains: Phytepsin 32 kDa subunit; Phytepsin 29 kDa subunit; Phytepsin 16 kDa subunit; Phytepsin 11 kDa subunit] Length = 508 Score = 173 bits (439), Expect = 3e-43 Identities = 94/178 (52%), Positives = 117/178 (65%), Gaps = 5/178 (2%) Frame = +3 Query: 39 LWILSCALLL-----GGACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHS 203 L +L+ LLL + ++GL+RI L K+ +D+ + A L+ E + L S G+ Sbjct: 8 LALLAAVLLLQTVLPAASEAEGLVRIALKKRPIDRNSRVATGLSGGEEQPLLS--GANPL 65 Query: 204 LGLSGDDIVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHH 383 DIV L NY++ QYFGEIGVGTPPQ FTVIFDTGSSNLWVPS+KCYFSIACYLH Sbjct: 66 RSEEEGDIVALKNYMNAQYFGEIGVGTPPQKFTVIFDTGSSNLWVPSAKCYFSIACYLHS 125 Query: 384 XXXXXXXXXXXXNGETCTISYGSGSIAGFFSEDSVLVGELVVKNQKFIETTREASPTF 557 NG+ I YG+GSIAG+FSEDSV VG+LVVK+Q+FIE T+E TF Sbjct: 126 RYKAGASSTYKKNGKPAAIQYGTGSIAGYFSEDSVTVGDLVVKDQEFIEATKEPGITF 183
>ASPR_CUCPE (O04057) Aspartic proteinase precursor (EC 3.4.23.-)| Length = 513 Score = 164 bits (416), Expect = 1e-40 Identities = 87/178 (48%), Positives = 117/178 (65%), Gaps = 4/178 (2%) Frame = +3 Query: 36 CLWILSCALLLGGACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRS---DDGSRHSL 206 CL++L ++ A +DGLLR+ L K +LD E AA++ ++ ++L++ + +L Sbjct: 12 CLFLLVSFNIVSSASNDGLLRVGLKKIKLDPENRLAARVESKDAEILKAAFRKYNPKGNL 71 Query: 207 GLSGD-DIVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHH 383 G S D DIV L NYLD QY+GEI +GTPPQ FTVIFDTGSSNLWV +C FS+AC+ H Sbjct: 72 GESSDTDIVALKNYLDAQYYGEIAIGTPPQKFTVIFDTGSSNLWV-LCECLFSVACHFHA 130 Query: 384 XXXXXXXXXXXXNGETCTISYGSGSIAGFFSEDSVLVGELVVKNQKFIETTREASPTF 557 NG + +I YG+G+++GFFS D+V VG+LVVK Q FIE TRE S TF Sbjct: 131 RYKSSRSSSYKKNGTSASIRYGTGAVSGFFSYDNVKVGDLVVKEQVFIEATREPSLTF 188
>CYPR1_CYNCA (P40782) Cyprosin precursor (EC 3.4.23.-) (Fragment)| Length = 473 Score = 154 bits (388), Expect = 2e-37 Identities = 72/132 (54%), Positives = 91/132 (68%), Gaps = 6/132 (4%) Frame = +3 Query: 180 SDDGSRHSLGLSGD------DIVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVP 341 +D +R G+ G+ +++ L NY+D QYFGEIG+GTPPQ FTVIFDTGSSNLWVP Sbjct: 19 NDANARRKYGVRGNFRDSDGELIALKNYMDAQYFGEIGIGTPPQKFTVIFDTGSSNLWVP 78 Query: 342 SSKCYFSIACYLHHXXXXXXXXXXXXNGETCTISYGSGSIAGFFSEDSVLVGELVVKNQK 521 SSKCYFS+AC H NG++ I YG+GSI+GFFS+DSV +G+L+VK Q Sbjct: 79 SSKCYFSVACLFHSKYRSTDSTTYKKNGKSAAIQYGTGSISGFFSQDSVKLGDLLVKEQD 138 Query: 522 FIETTREASPTF 557 FIE T+E TF Sbjct: 139 FIEATKEPGITF 150
>CATD_CLUHA (Q9DEX3) Cathepsin D precursor (EC 3.4.23.5)| Length = 396 Score = 127 bits (318), Expect = 3e-29 Identities = 69/163 (42%), Positives = 96/163 (58%), Gaps = 4/163 (2%) Frame = +3 Query: 81 SDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHSLGLSGDDIVP---LDNYLD 251 SD ++RI L K R + TL+ + L ++ LL + +H+ G + L NY+D Sbjct: 16 SDAIVRIPLKKFRSIRRTLSDSGLNVEQ--LLAGTNSLQHNQGFPSSNAPTPETLKNYMD 73 Query: 252 TQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFS-IACYLHHXXXXXXXXXXXXNGE 428 QY+GEIG+GTP Q FTV+FDTGSSNLW+PS C F+ IAC LHH NG Sbjct: 74 AQYYGEIGLGTPVQMFTVVFDTGSSNLWLPSIHCSFTDIACLLHHKYNGAKSSTYVKNGT 133 Query: 429 TCTISYGSGSIAGFFSEDSVLVGELVVKNQKFIETTREASPTF 557 I YGSGS++G+ S+DS +G++VV+ Q F E ++ F Sbjct: 134 EFAIQYGSGSLSGYLSQDSCTIGDIVVEKQLFGEAIKQPGVAF 176
>CATD_CHICK (Q05744) Cathepsin D precursor (EC 3.4.23.5) [Contains: Cathepsin D| light chain; Cathepsin D heavy chain] Length = 398 Score = 124 bits (312), Expect = 1e-28 Identities = 58/109 (53%), Positives = 72/109 (66%), Gaps = 1/109 (0%) Frame = +3 Query: 234 LDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCY-FSIACYLHHXXXXXXXXX 410 L NY+D QY+GEIG+GTPPQ FTV+FDTGSSNLWVPS C+ IAC LHH Sbjct: 70 LKNYMDAQYYGEIGIGTPPQKFTVVFDTGSSNLWVPSVHCHLLDIACLLHHKYDASKSST 129 Query: 411 XXXNGETCTISYGSGSIAGFFSEDSVLVGELVVKNQKFIETTREASPTF 557 NG I YG+GS++GF S+D+V +G L +KNQ F E ++ TF Sbjct: 130 YVENGTEFAIHYGTGSLSGFLSQDTVTLGNLKIKNQIFGEAVKQPGITF 178
>CARP_NEUCR (Q01294) Vacuolar protease A precursor (EC 3.4.23.-)| Length = 396 Score = 122 bits (305), Expect = 9e-28 Identities = 73/182 (40%), Positives = 103/182 (56%), Gaps = 11/182 (6%) Frame = +3 Query: 45 ILSCALLLGGACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSR---HSLGL- 212 +L+ A+LLG A + G+ + L K L E L + + Q L + G R H+ + Sbjct: 5 LLTAAMLLGSAQA-GVHTMKLKKVPL-AEQLESVPIDVQVQHLGQKYTGLRTESHTQAMF 62 Query: 213 -------SGDDIVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIAC 371 SG+ VP+ N+++ QYF EI +GTPPQ F V+ DTGSSNLWVPSS+C SIAC Sbjct: 63 KATDAQVSGNHPVPITNFMNAQYFSEITIGTPPQTFKVVLDTGSSNLWVPSSQC-GSIAC 121 Query: 372 YLHHXXXXXXXXXXXXNGETCTISYGSGSIAGFFSEDSVLVGELVVKNQKFIETTREASP 551 YLH+ NG + I YGSGS++GF S+D + +G++ + +Q F E T E Sbjct: 122 YLHNKYESSESSTYKKNGTSFKIEYGSGSLSGFVSQDRMTIGDITINDQLFAEATSEPGL 181 Query: 552 TF 557 F Sbjct: 182 AF 183
>CARP_YEAST (P07267) Saccharopepsin precursor (EC 3.4.23.25) (Aspartate| protease) (Proteinase A) (Proteinase YSCA) Length = 405 Score = 117 bits (292), Expect = 3e-26 Identities = 62/146 (42%), Positives = 82/146 (56%) Frame = +3 Query: 120 LDKETLTAAKLARQETKLLRSDDGSRHSLGLSGDDIVPLDNYLDTQYFGEIGVGTPPQNF 299 L ++ LT + A E R H G VPL NYL+ QY+ +I +GTPPQNF Sbjct: 50 LGQKYLTQFEKANPEVVFSRE-----HPFFTEGGHDVPLTNYLNAQYYTDITLGTPPQNF 104 Query: 300 TVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXXXXXXXNGETCTISYGSGSIAGFFSE 479 VI DTGSSNLWVPS++C S+AC+LH NG I YG+GS+ G+ S+ Sbjct: 105 KVILDTGSSNLWVPSNEC-GSLACFLHSKYDHEASSSYKANGTEFAIQYGTGSLEGYISQ 163 Query: 480 DSVLVGELVVKNQKFIETTREASPTF 557 D++ +G+L + Q F E T E TF Sbjct: 164 DTLSIGDLTIPKQDFAEATSEPGLTF 189
>CATEA_XENLA (Q805F3) Cathepsin E-A precursor (EC 3.4.23.34)| Length = 397 Score = 116 bits (291), Expect = 4e-26 Identities = 71/169 (42%), Positives = 97/169 (57%), Gaps = 3/169 (1%) Frame = +3 Query: 60 LLLGGACSDGLLRINLSKKRLDKETLTA-AKLARQETKLLRSDDGSRHSLGLSGDDIV-- 230 LLL GL+R+ L +++ ++TL KL+ T+ + D +++ S D Sbjct: 7 LLLFATLVYGLIRVPLKRQKSIRKTLKEKGKLSHIWTQ--QGIDMVQYTDSCSNDQAPSE 64 Query: 231 PLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXXXX 410 PL NY+D +YFGEI VGTPPQNFTVIFDTGSSNLWVPS C S AC H Sbjct: 65 PLINYMDVEYFGEISVGTPPQNFTVIFDTGSSNLWVPSVYC-ISQACAQHDRFQPQLSST 123 Query: 411 XXXNGETCTISYGSGSIAGFFSEDSVLVGELVVKNQKFIETTREASPTF 557 NG ++ YG+GS++G D+V V ++V+NQ+F E+ E TF Sbjct: 124 YESNGNNFSLQYGTGSLSGVIGIDAVTVEGILVQNQQFGESVSEPGSTF 172
>NAPSA_HUMAN (O96009) Napsin-A precursor (EC 3.4.23.-) (Napsin-1) (NAPA)| (TA01/TA02) (Aspartyl protease 4) (Asp 4) (ASP4) Length = 420 Score = 116 bits (291), Expect = 4e-26 Identities = 57/111 (51%), Positives = 68/111 (61%), Gaps = 1/111 (0%) Frame = +3 Query: 228 VPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKC-YFSIACYLHHXXXXXXX 404 VPL NY D QYFGEIG+GTPPQNFTV FDTGSSNLWVPS +C +FS+ C+LHH Sbjct: 68 VPLSNYRDVQYFGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRFDPKAS 127 Query: 405 XXXXXNGETCTISYGSGSIAGFFSEDSVLVGELVVKNQKFIETTREASPTF 557 NG I YG+G + G SED + +G + + F E E S F Sbjct: 128 SSFQANGTKFAIQYGTGRVDGILSEDKLTIGGIKGASVIFGEALWEPSLVF 178
>CATD_RAT (P24268) Cathepsin D precursor (EC 3.4.23.5) [Contains: Cathepsin D| 12 kDa light chain; Cathepsin D 9 kDa light chain; Cathepsin D 34 kDa heavy chain; Cathepsin D 30 kDa heavy chain] Length = 407 Score = 116 bits (290), Expect = 5e-26 Identities = 73/179 (40%), Positives = 99/179 (55%), Gaps = 13/179 (7%) Frame = +3 Query: 60 LLLG--GACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHSLGLSGDDIVP 233 L+LG A S L+RI L K + T+T ++ L+ +++S+ S P Sbjct: 9 LILGLLDASSSALIRIPLRKFTSIRRTMT--EVGGSVEDLILKGPITKYSMQSSPRTKEP 66 Query: 234 ----LDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKC-YFSIACYLHHXXXXX 398 L NYLD QY+GEIG+GTPPQ FTV+FDTGSSNLWVPS C IAC++HH Sbjct: 67 VSELLKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSD 126 Query: 399 XXXXXXXNGETCTISYGSGSIAGFFSEDSVLV------GELVVKNQKFIETTREASPTF 557 NG + I YGSGS++G+ S+D+V V G + V+ Q F E T++ F Sbjct: 127 KSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGVVF 185
>NAPSA_MOUSE (O09043) Napsin-A precursor (EC 3.4.23.-) (Kidney-derived aspartic| protease-like protein) (KDAP-1) (KAP) Length = 419 Score = 115 bits (289), Expect = 6e-26 Identities = 64/156 (41%), Positives = 87/156 (55%), Gaps = 3/156 (1%) Frame = +3 Query: 39 LWILSCALLLGGACSDG--LLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHSLGL 212 L +L LLLG + L+R+ L + L L Q +L SR S Sbjct: 4 LLLLLLCLLLGNLEPEEAKLIRVPLQRIHLGHRILNPLNGWEQLAEL------SRTSTSG 57 Query: 213 SGDDIVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKC-YFSIACYLHHXX 389 VPL +++TQYFG IG+GTPPQNFTV+FDTGSSNLWVPS++C +FS+AC+ HH Sbjct: 58 GNPSFVPLSKFMNTQYFGTIGLGTPPQNFTVVFDTGSSNLWVPSTRCHFFSLACWFHHRF 117 Query: 390 XXXXXXXXXXNGETCTISYGSGSIAGFFSEDSVLVG 497 NG I YG+G ++G S+D++ +G Sbjct: 118 NPKASSSFRPNGTKFAIQYGTGRLSGILSQDNLTIG 153
>CATD_HUMAN (P07339) Cathepsin D precursor (EC 3.4.23.5) [Contains: Cathepsin D| light chain; Cathepsin D heavy chain] Length = 412 Score = 115 bits (288), Expect = 8e-26 Identities = 72/187 (38%), Positives = 100/187 (53%), Gaps = 16/187 (8%) Frame = +3 Query: 45 ILSCALLLGGACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHSLGLSGDD 224 +L AL L A + L+RI L K + T++ ++ L+ S++S + Sbjct: 6 LLPLALCLLAAPASALVRIPLHKFTSIRRTMS--EVGGSVEDLIAKGPVSKYSQAVPAVT 63 Query: 225 IVP----LDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKC-YFSIACYLHHXX 389 P L NY+D QY+GEIG+GTPPQ FTV+FDTGSSNLWVPS C IAC++HH Sbjct: 64 EGPIPEVLKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKY 123 Query: 390 XXXXXXXXXXNGETCTISYGSGSIAGFFSEDSVLV-----------GELVVKNQKFIETT 536 NG + I YGSGS++G+ S+D+V V G + V+ Q F E T Sbjct: 124 NSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCQSASSASALGGVKVERQVFGEAT 183 Query: 537 REASPTF 557 ++ TF Sbjct: 184 KQPGITF 190
>CATEB_XENLA (Q805F2) Cathepsin E-B precursor (EC 3.4.23.34)| Length = 397 Score = 115 bits (288), Expect = 8e-26 Identities = 68/160 (42%), Positives = 92/160 (57%), Gaps = 3/160 (1%) Frame = +3 Query: 87 GLLRINLSK-KRLDKETLTAAKLARQETKLLRSDDGSRHSLGLSGDDIV--PLDNYLDTQ 257 GL+R+ L + K + K KL+ T+ + D +++ + D PL NY+D Q Sbjct: 16 GLIRVPLKRQKSIRKTPKEKGKLSHVWTQ--QGIDMVQYTDSCNNDQAPSEPLINYMDVQ 73 Query: 258 YFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXXXXXXXNGETCT 437 YFGEI +GTPPQNFTVIFDTGSSNLWVPS C S AC H+ NG + Sbjct: 74 YFGEISIGTPPQNFTVIFDTGSSNLWVPSVYC-ISPACAQHNRFQPQLSSTYESNGNNFS 132 Query: 438 ISYGSGSIAGFFSEDSVLVGELVVKNQKFIETTREASPTF 557 + YG+GS++G DSV V ++V+NQ+F E+ E TF Sbjct: 133 LQYGTGSLSGVIGIDSVTVEGILVQNQQFGESVSEPGSTF 172
>RENI_CALJA (Q9TSZ1) Renin precursor (EC 3.4.23.15) (Angiotensinogenase)| Length = 400 Score = 114 bits (284), Expect = 2e-25 Identities = 63/160 (39%), Positives = 90/160 (56%), Gaps = 1/160 (0%) Frame = +3 Query: 60 LLLGGACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHSLGLSGDDIVPLD 239 LLL G+C+ GL + KR+ + + + + + +E + + G ++ V L Sbjct: 14 LLLWGSCTFGLPTETTTFKRISLKRMPSIRESLKERGVDMARLGPERMALVNITSSVILT 73 Query: 240 NYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKC-YFSIACYLHHXXXXXXXXXXX 416 NY+DTQY+GEIG+GTPPQ F V+FDTGSSN+WVPSSKC AC H Sbjct: 74 NYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSSYK 133 Query: 417 XNGETCTISYGSGSIAGFFSEDSVLVGELVVKNQKFIETT 536 NG T+ Y +G+++GF S+D + VG + V Q F E T Sbjct: 134 HNGTELTLRYSTGTVSGFLSQDVITVGGITV-TQTFGEVT 172
>CATD_CANFA (Q4LAL9) Cathepsin D precursor (EC 3.4.23.5)| Length = 410 Score = 113 bits (282), Expect = 4e-25 Identities = 73/185 (39%), Positives = 101/185 (54%), Gaps = 14/185 (7%) Frame = +3 Query: 45 ILSCALLLGGACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHSLG---LS 215 +L L L A + L+RI L K + T+T +L L+ S+++ G ++ Sbjct: 6 LLLLVLGLLAAPAAALVRIPLHKFTSVRRTMT--ELGGPVEDLIAKGPISKYAQGAPAVT 63 Query: 216 GDDIVP-LDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKC-YFSIACYLHHXX 389 G I L NY+D QY+GEIG+GTPPQ FTV+FDTGSSNLWVPS C IAC++HH Sbjct: 64 GGPIPEMLRNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKY 123 Query: 390 XXXXXXXXXXNGETCTISYGSGSIAGFFSEDSVLV---------GELVVKNQKFIETTRE 542 NG + I YGSGS++G+ S+D+V V + V+ Q F E T++ Sbjct: 124 NSGKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSALSGLAGIKVERQTFGEATKQ 183 Query: 543 ASPTF 557 TF Sbjct: 184 PGITF 188
>RENI_CANFA (Q6DYE7) Renin precursor (EC 3.4.23.15) (Angiotensinogenase)| Length = 403 Score = 112 bits (280), Expect = 7e-25 Identities = 72/167 (43%), Positives = 90/167 (53%), Gaps = 8/167 (4%) Frame = +3 Query: 60 LLLGGACSDGL-------LRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHSLGLSG 218 L+L G+C+ GL RI L K +E+L + + R S G S Sbjct: 13 LVLWGSCTFGLPADTGAFRRIFLKKMPSIRESLKERGVDVAGLGAEWNQFTKRLSSGNST 72 Query: 219 DDIVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCY-FSIACYLHHXXXX 395 +V L NYLDTQY+GEIG+GTPPQ F V+FDTGS+NLWVPS++C AC +H Sbjct: 73 SPVV-LTNYLDTQYYGEIGIGTPPQTFKVVFDTGSANLWVPSTRCSPLYTACEIHCLYDS 131 Query: 396 XXXXXXXXNGETCTISYGSGSIAGFFSEDSVLVGELVVKNQKFIETT 536 NG T TI YGSG + GF S+D V VG + V Q F E T Sbjct: 132 SESSSYMENGTTFTIRYGSGKVKGFLSQDMVTVGGITV-TQTFGEVT 177
>ASPP_AEDAE (Q03168) Lysosomal aspartic protease precursor (EC 3.4.23.-)| Length = 387 Score = 112 bits (280), Expect = 7e-25 Identities = 56/117 (47%), Positives = 71/117 (60%), Gaps = 1/117 (0%) Frame = +3 Query: 210 LSGDDIVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYF-SIACYLHHX 386 +SG PL NYLD QY+G I +GTPPQ+F V+FDTGSSNLWVPS +C F +IAC +H+ Sbjct: 52 VSGPVPEPLSNYLDAQYYGAITIGTPPQSFKVVFDTGSSNLWVPSKECSFTNIACLMHNK 111 Query: 387 XXXXXXXXXXXNGETCTISYGSGSIAGFFSEDSVLVGELVVKNQKFIETTREASPTF 557 NG I YGSGS++G+ S D+V +G + V Q F E E F Sbjct: 112 YNAKKSSTFEKNGTAFHIQYGSGSLSGYLSTDTVGLGGVSVTKQTFAEAINEPGLVF 168
>PEPC_RAT (P04073) Gastricsin precursor (EC 3.4.23.3) (Pepsinogen C)| Length = 392 Score = 111 bits (277), Expect = 2e-24 Identities = 65/169 (38%), Positives = 88/169 (52%), Gaps = 2/169 (1%) Frame = +3 Query: 57 ALLLGGACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHSLGLSGDDIVPL 236 ALL LLR+ L K + +ET+ + + K + D G ++ G GD V Sbjct: 7 ALLCLPLLEASLLRVPLRKMKSIRETMKEQGVLKDFLKTHKYDPGQKYHFGNFGDYSVLY 66 Query: 237 DN--YLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXXXX 410 + Y+D YFGEI +GTPPQNF V+FDTGSSNLWV S C S AC H Sbjct: 67 EPMAYMDASYFGEISIGTPPQNFLVLFDTGSSNLWVSSVYCQ-SEACTTHARFNPSKSST 125 Query: 411 XXXNGETCTISYGSGSIAGFFSEDSVLVGELVVKNQKFIETTREASPTF 557 G+T ++ YG+GS+ GFF D++ V + V NQ+F + E F Sbjct: 126 YYTEGQTFSLQYGTGSLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNF 174
>CATD_PIG (P00795) Cathepsin D precursor (EC 3.4.23.5) [Contains: Cathepsin D| light chain; Cathepsin D heavy chain] Length = 345 Score = 111 bits (277), Expect = 2e-24 Identities = 56/119 (47%), Positives = 70/119 (58%), Gaps = 11/119 (9%) Frame = +3 Query: 234 LDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKC-YFSIACYLHHXXXXXXXXX 410 L NY+D QY+GEIG+GTPPQ FTV+FDTGSSNLWVPS C IAC++HH Sbjct: 7 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSGKSST 66 Query: 411 XXXNGETCTISYGSGSIAGFFSEDSVL----------VGELVVKNQKFIETTREASPTF 557 NG T I YGSGS++G+ S + VG + V+ Q F E T++ TF Sbjct: 67 YVKNGTTFAIHYGSGSLSGYLSSQDTVSVPCNSALSGVGGIKVERQTFGEATKQPGLTF 125
>RENI1_MOUSE (P06281) Renin-1 precursor (EC 3.4.23.15) (Angiotensinogenase)| (Kidney renin) Length = 402 Score = 111 bits (277), Expect = 2e-24 Identities = 57/104 (54%), Positives = 67/104 (64%), Gaps = 1/104 (0%) Frame = +3 Query: 228 VPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKC-YFSIACYLHHXXXXXXX 404 V L NYL+TQY+GEIG+GTPPQ F VIFDTGS+NLWVPS+KC +AC +H Sbjct: 74 VVLTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDS 133 Query: 405 XXXXXNGETCTISYGSGSIAGFFSEDSVLVGELVVKNQKFIETT 536 NG TI YGSG + GF S+DSV VG + V Q F E T Sbjct: 134 SSYMENGSDFTIHYGSGRVKGFLSQDSVTVGGITV-TQTFGEVT 176
>RENI_PANTR (P60016) Renin precursor (EC 3.4.23.15) (Angiotensinogenase)| Length = 406 Score = 111 bits (277), Expect = 2e-24 Identities = 65/167 (38%), Positives = 94/167 (56%), Gaps = 8/167 (4%) Frame = +3 Query: 60 LLLGGACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDG-------SRHSLGLSG 218 LLL G+C+ GL + KR+ + + + + + +E + + G R +LG + Sbjct: 14 LLLWGSCTFGLPTDTTTFKRIFLKRMPSIRESLKERGVDMARLGPEWSQPMKRLTLGNTT 73 Query: 219 DDIVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKC-YFSIACYLHHXXXX 395 ++ L NY+DTQY+GEIG+GTPPQ F V+FDTGSSN+WVPSSKC AC H Sbjct: 74 SSVI-LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDA 132 Query: 396 XXXXXXXXNGETCTISYGSGSIAGFFSEDSVLVGELVVKNQKFIETT 536 NG T+ Y +G+++GF S+D + VG + V Q F E T Sbjct: 133 SDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGGITV-TQMFGEVT 178
>RENI_MACMU (Q6DLW5) Renin precursor (EC 3.4.23.15) (Angiotensinogenase)| Length = 406 Score = 111 bits (277), Expect = 2e-24 Identities = 65/167 (38%), Positives = 94/167 (56%), Gaps = 8/167 (4%) Frame = +3 Query: 60 LLLGGACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDG-------SRHSLGLSG 218 LLL G+C+ GL + KR+ + + + + + +E + + G R +LG + Sbjct: 14 LLLWGSCTFGLPTDTTTFKRIFLKRMPSIRESLKERGVDMARLGPEWSQPMKRLALGNTT 73 Query: 219 DDIVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKC-YFSIACYLHHXXXX 395 ++ L NY+DTQY+GEIG+GTPPQ F V+FDTGSSN+WVPSSKC AC H Sbjct: 74 SSVI-LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDA 132 Query: 396 XXXXXXXXNGETCTISYGSGSIAGFFSEDSVLVGELVVKNQKFIETT 536 NG T+ Y +G+++GF S+D + VG + V Q F E T Sbjct: 133 SDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGGITV-TQMFGEVT 178
>RENI_MACFA (Q6DLS0) Renin precursor (EC 3.4.23.15) (Angiotensinogenase)| Length = 406 Score = 111 bits (277), Expect = 2e-24 Identities = 65/167 (38%), Positives = 94/167 (56%), Gaps = 8/167 (4%) Frame = +3 Query: 60 LLLGGACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDG-------SRHSLGLSG 218 LLL G+C+ GL + KR+ + + + + + +E + + G R +LG + Sbjct: 14 LLLWGSCTFGLPTDTTTFKRIFLKRMPSIRESLKERGVDMARLGPEWSQPMKRLALGNTT 73 Query: 219 DDIVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKC-YFSIACYLHHXXXX 395 ++ L NY+DTQY+GEIG+GTPPQ F V+FDTGSSN+WVPSSKC AC H Sbjct: 74 SSVI-LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDA 132 Query: 396 XXXXXXXXNGETCTISYGSGSIAGFFSEDSVLVGELVVKNQKFIETT 536 NG T+ Y +G+++GF S+D + VG + V Q F E T Sbjct: 133 SDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGGITV-TQMFGEVT 178
>RENI_HUMAN (P00797) Renin precursor (EC 3.4.23.15) (Angiotensinogenase)| Length = 406 Score = 111 bits (277), Expect = 2e-24 Identities = 65/167 (38%), Positives = 94/167 (56%), Gaps = 8/167 (4%) Frame = +3 Query: 60 LLLGGACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDG-------SRHSLGLSG 218 LLL G+C+ GL + KR+ + + + + + +E + + G R +LG + Sbjct: 14 LLLWGSCTFGLPTDTTTFKRIFLKRMPSIRESLKERGVDMARLGPEWSQPMKRLTLGNTT 73 Query: 219 DDIVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKC-YFSIACYLHHXXXX 395 ++ L NY+DTQY+GEIG+GTPPQ F V+FDTGSSN+WVPSSKC AC H Sbjct: 74 SSVI-LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDA 132 Query: 396 XXXXXXXXNGETCTISYGSGSIAGFFSEDSVLVGELVVKNQKFIETT 536 NG T+ Y +G+++GF S+D + VG + V Q F E T Sbjct: 133 SDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGGITV-TQMFGEVT 178
>PEPC_CALJA (Q9N2D3) Gastricsin precursor (EC 3.4.23.3) (Pepsinogen C)| Length = 388 Score = 110 bits (275), Expect = 3e-24 Identities = 60/156 (38%), Positives = 85/156 (54%) Frame = +3 Query: 90 LLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHSLGLSGDDIVPLDNYLDTQYFGE 269 ++++ L K + +ET+ L + K + D ++ + P+D Y+D YFGE Sbjct: 18 VVKVPLKKFKSIRETMKEKGLLWEFLKTHKHDPARKYRVSDLSVSYEPMD-YMDAAYFGE 76 Query: 270 IGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXXXXXXXNGETCTISYG 449 I +GTPPQNF V+FDTGSSNLWVPS C S AC H NG+T ++ YG Sbjct: 77 ISIGTPPQNFLVLFDTGSSNLWVPSVYCQ-SQACTSHSRFNPSASSTYSSNGQTFSLQYG 135 Query: 450 SGSIAGFFSEDSVLVGELVVKNQKFIETTREASPTF 557 SGS+ GFF D++ V + V NQ+F + E F Sbjct: 136 SGSLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNF 171
>RENI2_MOUSE (P00796) Renin-2 precursor (EC 3.4.23.15) (Angiotensinogenase)| (Submandibular gland renin) [Contains: Renin-2 heavy chain; Renin-2 light chain] Length = 401 Score = 110 bits (275), Expect = 3e-24 Identities = 56/104 (53%), Positives = 68/104 (65%), Gaps = 1/104 (0%) Frame = +3 Query: 228 VPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKC-YFSIACYLHHXXXXXXX 404 V L NYL++QY+GEIG+GTPPQ F VIFDTGS+NLWVPS+KC +AC +H Sbjct: 73 VVLTNYLNSQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDS 132 Query: 405 XXXXXNGETCTISYGSGSIAGFFSEDSVLVGELVVKNQKFIETT 536 NG+ TI YGSG + GF S+DSV VG + V Q F E T Sbjct: 133 SSYMENGDDFTIHYGSGRVKGFLSQDSVTVGGITV-TQTFGEVT 175
>CATD_SHEEP (Q9MZS8) Cathepsin D precursor (EC 3.4.23.5) (Fragment)| Length = 365 Score = 110 bits (274), Expect = 3e-24 Identities = 55/118 (46%), Positives = 71/118 (60%), Gaps = 10/118 (8%) Frame = +3 Query: 234 LDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKC-YFSIACYLHHXXXXXXXXX 410 L NY+D QY+GEIG+GTPPQ FTV+FDTGS+NLWVPS C IAC++HH Sbjct: 46 LTNYMDAQYYGEIGIGTPPQCFTVVFDTGSANLWVPSIHCKLLDIACWVHHKYNSDKSST 105 Query: 411 XXXNGETCTISYGSGSIAGFFSEDSVLV---------GELVVKNQKFIETTREASPTF 557 NG T I YGSGS++G+ S+D+V V G + V+ Q F E ++ F Sbjct: 106 YVKNGTTFDIHYGSGSLSGYLSQDTVSVPCNPSSSSPGGVTVQRQTFGEAIKQPGVVF 163
>RENI_SHEEP (P52115) Renin precursor (EC 3.4.23.15) (Angiotensinogenase)| Length = 400 Score = 109 bits (272), Expect = 6e-24 Identities = 57/104 (54%), Positives = 65/104 (62%), Gaps = 1/104 (0%) Frame = +3 Query: 228 VPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCY-FSIACYLHHXXXXXXX 404 V L NYLDTQY+GEIG+GTPPQ F VIFDTGS+NLWVPS+KC AC +H Sbjct: 70 VVLTNYLDTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSPLYTACEIHSLYDSLES 129 Query: 405 XXXXXNGETCTISYGSGSIAGFFSEDSVLVGELVVKNQKFIETT 536 NG TI YGSG + GF S+D V VG + V Q F E T Sbjct: 130 SSYVENGTEFTIYYGSGKVKGFLSQDLVTVGGITV-TQTFGEVT 172
>PEPC_MOUSE (Q9D7R7) Gastricsin precursor (EC 3.4.23.3) (Pepsinogen C)| Length = 392 Score = 109 bits (272), Expect = 6e-24 Identities = 65/172 (37%), Positives = 90/172 (52%), Gaps = 2/172 (1%) Frame = +3 Query: 48 LSCALLLGGACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHSLGLSGDDI 227 L C LL A L+R+ L K + +ET+ + + K + D G ++ G GD Sbjct: 8 LLCLPLLEAA----LIRVPLKKMKSIRETMKEQGVLKDFLKNHKYDPGQKYHFGKFGDYS 63 Query: 228 VPLDN--YLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXX 401 V + Y+D Y+GEI +GTPPQNF V+FDTGSSNLWV S C S AC H Sbjct: 64 VLYEPMAYMDASYYGEISIGTPPQNFLVLFDTGSSNLWVSSVYCQ-SEACTTHTRYNPSK 122 Query: 402 XXXXXXNGETCTISYGSGSIAGFFSEDSVLVGELVVKNQKFIETTREASPTF 557 G+T ++ YG+GS+ GFF D++ V + V NQ+F + E F Sbjct: 123 SSTYYTQGQTFSLQYGTGSLTGFFGYDTLRVQSIQVPNQEFGLSENEPGTNF 174
>CATD_MOUSE (P18242) Cathepsin D precursor (EC 3.4.23.5)| Length = 410 Score = 108 bits (271), Expect = 8e-24 Identities = 65/180 (36%), Positives = 92/180 (51%), Gaps = 14/180 (7%) Frame = +3 Query: 60 LLLGGACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHSLGLSGDDIVP-- 233 L+LG S I + ++ T ++ L+ +++S+ S P Sbjct: 9 LILGLLASSSFAIIRIPLRKFTSIRRTMTEVGGSVEDLILKGPITKYSMQSSPKTTEPVS 68 Query: 234 --LDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKC-YFSIACYLHHXXXXXXX 404 L NYLD QY+G+IG+GTPPQ FTV+FDTGSSNLWVPS C IAC++HH Sbjct: 69 ELLKNYLDAQYYGDIGIGTPPQCFTVVFDTGSSNLWVPSIHCKILDIACWVHHKYNSDKS 128 Query: 405 XXXXXNGETCTISYGSGSIAGFFSEDSVLV---------GELVVKNQKFIETTREASPTF 557 NG + I YGSGS++G+ S+D+V V + V+ Q F E T++ F Sbjct: 129 STYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDQSKARGIKVEKQIFGEATKQPGIVF 188
>PEPC_HUMAN (P20142) Gastricsin precursor (EC 3.4.23.3) (Pepsinogen C)| Length = 388 Score = 108 bits (271), Expect = 8e-24 Identities = 64/171 (37%), Positives = 90/171 (52%) Frame = +3 Query: 45 ILSCALLLGGACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHSLGLSGDD 224 +L C LL A ++++ L K + +ET+ L + + + D ++ G Sbjct: 7 VLVCLQLLEAA----VVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVT 62 Query: 225 IVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXX 404 P+ Y+D YFGEI +GTPPQNF V+FDTGSSNLWVPS C S AC H Sbjct: 63 YEPMA-YMDAAYFGEISIGTPPQNFLVLFDTGSSNLWVPSVYCQ-SQACTSHSRFNPSES 120 Query: 405 XXXXXNGETCTISYGSGSIAGFFSEDSVLVGELVVKNQKFIETTREASPTF 557 NG+T ++ YGSGS+ GFF D++ V + V NQ+F + E F Sbjct: 121 STYSTNGQTFSLQYGSGSLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNF 171
>CARPV_CANAL (P10977) Vacuolar aspartic protease precursor (EC 3.4.23.-)| (Aspartate protease) (ACP) Length = 419 Score = 108 bits (271), Expect = 8e-24 Identities = 54/109 (49%), Positives = 66/109 (60%) Frame = +3 Query: 231 PLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXXXX 410 PL NYL+ QYF EI +GTP Q F VI DTGSSNLWVPS C S+AC+LH Sbjct: 95 PLTNYLNAQYFTEIQIGTPGQPFKVILDTGSSNLWVPSQDC-TSLACFLHAKYDHDASST 153 Query: 411 XXXNGETCTISYGSGSIAGFFSEDSVLVGELVVKNQKFIETTREASPTF 557 NG +I YGSGS+ G+ S+D + +G+LV+ Q F E T E F Sbjct: 154 YKVNGSEFSIQYGSGSMEGYISQDVLTIGDLVIPGQDFAEATSEPGLAF 202
>RENI_RAT (P08424) Renin precursor (EC 3.4.23.15) (Angiotensinogenase)| Length = 402 Score = 108 bits (270), Expect = 1e-23 Identities = 56/104 (53%), Positives = 66/104 (63%), Gaps = 1/104 (0%) Frame = +3 Query: 228 VPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKC-YFSIACYLHHXXXXXXX 404 V L NYLDTQY+GEIG+GTP Q F VIFDTGS+NLWVPS+KC AC +H+ Sbjct: 74 VVLTNYLDTQYYGEIGIGTPSQTFKVIFDTGSANLWVPSTKCGPLYTACEIHNLYDSSES 133 Query: 405 XXXXXNGETCTISYGSGSIAGFFSEDSVLVGELVVKNQKFIETT 536 NG TI YGSG + GF S+D V VG ++V Q F E T Sbjct: 134 SSYMENGTEFTIHYGSGKVKGFLSQDVVTVGGIIV-TQTFGEVT 176
>PEPA_PIG (P00791) Pepsin A precursor (EC 3.4.23.1)| Length = 386 Score = 108 bits (269), Expect = 1e-23 Identities = 63/164 (38%), Positives = 94/164 (57%), Gaps = 3/164 (1%) Frame = +3 Query: 42 WILSCALLLGGACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRH---SLGL 212 W+L +L++ C L+++ L +K+ ++ L + K + + S++ + L Sbjct: 3 WLLLLSLVVLSEC---LVKVPLVRKKSLRQNLIKNGKLKDFLKTHKHNPASKYFPEAAAL 59 Query: 213 SGDDIVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXX 392 GD+ PL+NYLDT+YFG IG+GTP Q+FTVIFDTGSSNLWVPS C S+AC H+ Sbjct: 60 IGDE--PLENYLDTEYFGTIGIGTPAQDFTVIFDTGSSNLWVPSVYC-SSLACSDHNQFN 116 Query: 393 XXXXXXXXXNGETCTISYGSGSIAGFFSEDSVLVGELVVKNQKF 524 + +I+YG+GS+ G D+V VG + NQ F Sbjct: 117 PDDSSTFEATSQELSITYGTGSMTGILGYDTVQVGGISDTNQIF 160
>PEPA4_MACFU (P27678) Pepsin A-4 precursor (EC 3.4.23.1) (Pepsin I/II)| Length = 388 Score = 108 bits (269), Expect = 1e-23 Identities = 61/164 (37%), Positives = 89/164 (54%), Gaps = 3/164 (1%) Frame = +3 Query: 42 WILSCALLLGGACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHSLGLSGD 221 W+L L+ C + ++ L +K+ + L+ L + K + S++ Sbjct: 3 WLLLLGLVALSECI--IYKVPLVRKKSLRRNLSEHGLLKDFLKKHNLNPASKYFPQAEAP 60 Query: 222 DIV---PLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXX 392 ++ PL+NYLD +YFG IG+GTP QNFTV+FDTGSSNLWVPS CY S+AC H+ Sbjct: 61 TLIDEQPLENYLDVEYFGTIGIGTPAQNFTVVFDTGSSNLWVPSVYCY-SLACMDHNLFN 119 Query: 393 XXXXXXXXXNGETCTISYGSGSIAGFFSEDSVLVGELVVKNQKF 524 +T +I+YG+GS+ G D+V VG + NQ F Sbjct: 120 PQDSSTYRATSKTVSITYGTGSMTGILGYDTVKVGGISDTNQIF 163
>CATE_RANCA (Q800A0) Cathepsin E precursor (EC 3.4.23.34)| Length = 397 Score = 107 bits (268), Expect = 2e-23 Identities = 64/160 (40%), Positives = 89/160 (55%), Gaps = 3/160 (1%) Frame = +3 Query: 87 GLLRINLSKKRLDKETLTA-AKLARQETKLLRSDDGSRHSLGLSGDDIV--PLDNYLDTQ 257 G++R+ L +++ ++ L KL+ TK + ++ + S S + PL NYLD + Sbjct: 16 GIIRVPLKRQKSMRKILKEKGKLSHLWTK--QGNEFLQLSDSCSSPETASEPLMNYLDVE 73 Query: 258 YFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXXXXXXXNGETCT 437 YFG+I +GTPPQ FTVIFDTGSSNLWVPS C S AC H+ NGE Sbjct: 74 YFGQISIGTPPQQFTVIFDTGSSNLWVPSIYC-TSQACTKHNRYRPSESTTYVSNGEAFF 132 Query: 438 ISYGSGSIAGFFSEDSVLVGELVVKNQKFIETTREASPTF 557 I YG+G++ G D V V + V++Q F E+ E TF Sbjct: 133 IQYGTGNLTGILGIDQVTVQGITVQSQTFAESVSEPGSTF 172
>PEPA1_RABIT (P28712) Pepsin II-1 precursor (EC 3.4.23.1) (Pepsin A)| Length = 387 Score = 107 bits (267), Expect = 2e-23 Identities = 54/108 (50%), Positives = 67/108 (62%) Frame = +3 Query: 234 LDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXXXXX 413 L+NYLD +YFG I +GTPPQ FTVIFDTGSSNLWVPS+ C S+AC+LH Sbjct: 67 LENYLDAEYFGTISIGTPPQEFTVIFDTGSSNLWVPSTYC-SSLACFLHKRFNPDDSSTF 125 Query: 414 XXNGETCTISYGSGSIAGFFSEDSVLVGELVVKNQKFIETTREASPTF 557 ET +I+YG+GS+ G D+V VG + NQ F + E TF Sbjct: 126 QATSETLSITYGTGSMTGILGYDTVKVGNIEDTNQIFGLSKTEPGITF 173
>CATE_CAVPO (P25796) Cathepsin E precursor (EC 3.4.23.34)| Length = 391 Score = 107 bits (267), Expect = 2e-23 Identities = 68/171 (39%), Positives = 88/171 (51%) Frame = +3 Query: 45 ILSCALLLGGACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHSLGLSGDD 224 +L LL G L R+ LS++ ++ L A Q T+L +S + + Sbjct: 6 LLLLVLLELGQAPGALHRVPLSRRESLRKKLRAQG---QLTELWKSQNLNMDQCSTIQSA 62 Query: 225 IVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXX 404 PL NYLD +YFG I +G+PPQNFTVIFDTGSSNLWVPS C S AC H Sbjct: 63 NEPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC-TSPACQTHPVFHPSLS 121 Query: 405 XXXXXNGETCTISYGSGSIAGFFSEDSVLVGELVVKNQKFIETTREASPTF 557 G + +I YG+GS+ G D V V L V Q+F E+ +E TF Sbjct: 122 STYREVGNSFSIQYGTGSLTGIIGADQVSVEGLTVVGQQFGESVQEPGKTF 172
>PEPA3_RABIT (P27822) Pepsin-3 precursor (EC 3.4.23.1) (Pepsin III) (Pepsin A)| Length = 387 Score = 107 bits (266), Expect = 3e-23 Identities = 65/164 (39%), Positives = 92/164 (56%), Gaps = 3/164 (1%) Frame = +3 Query: 42 WILSCALLLGGACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHSLGLSGD 221 W+L LL C + ++ L +K+ ++ L L + K + +++ L + Sbjct: 3 WLLLLGLLALSECI--IHKVPLVRKKSLRKNLIEKGLLKDYLKTHTPNLATKY-LPKAAF 59 Query: 222 DIVP---LDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXX 392 D VP L+NYLDT+YFG IG+GTP Q+FTVIFDTGSSNLWVPS C S AC +H+ Sbjct: 60 DSVPTETLENYLDTEYFGTIGIGTPAQDFTVIFDTGSSNLWVPSVYC-SSAACSVHNQFN 118 Query: 393 XXXXXXXXXNGETCTISYGSGSIAGFFSEDSVLVGELVVKNQKF 524 E+ +I+YG+GS+ GF D+V VG + NQ F Sbjct: 119 PEDSSTFQATSESLSITYGTGSMTGFLGYDTVKVGNIEDTNQIF 162
>PEPC_MONDO (Q689Z7) Gastricsin precursor (EC 3.4.23.3) (Pepsinogen C)| Length = 391 Score = 107 bits (266), Expect = 3e-23 Identities = 55/108 (50%), Positives = 68/108 (62%) Frame = +3 Query: 231 PLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXXXX 410 P+ NYLD+ YFGEI +GTPPQNF V+FDTGSSNLWVPS+ C S AC H+ Sbjct: 66 PITNYLDSFYFGEISIGTPPQNFLVLFDTGSSNLWVPSTYCQ-SQACSNHNRFSPSQSST 124 Query: 411 XXXNGETCTISYGSGSIAGFFSEDSVLVGELVVKNQKFIETTREASPT 554 G+T T+SYGSGS+ D+V V +VV NQ+F E+ PT Sbjct: 125 FTNGGQTYTLSYGSGSLTVVLGYDTVTVQNIVVSNQEF--GLSESEPT 170
>PEPC_MACFU (P03955) Gastricsin precursor (EC 3.4.23.3) (Pepsinogen C)| (Fragment) Length = 377 Score = 107 bits (266), Expect = 3e-23 Identities = 59/156 (37%), Positives = 84/156 (53%) Frame = +3 Query: 90 LLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHSLGLSGDDIVPLDNYLDTQYFGE 269 ++++ L K + +ET+ L + + + D ++ G P+ Y+D YFGE Sbjct: 7 VVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYHFGDLSVSYEPMA-YMDAAYFGE 65 Query: 270 IGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXXXXXXXNGETCTISYG 449 I +GTPPQNF V+FDTGSSNLWVPS C S AC H NG+T ++ YG Sbjct: 66 ISIGTPPQNFLVLFDTGSSNLWVPSVYCQ-SQACTSHSRFNPSESSTYSTNGQTFSLQYG 124 Query: 450 SGSIAGFFSEDSVLVGELVVKNQKFIETTREASPTF 557 SGS+ GFF D++ V + V NQ+F + E F Sbjct: 125 SGSLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNF 160
>PEPA2_RABIT (P27821) Pepsin II-2/3 precursor (EC 3.4.23.1) (Pepsin A)| Length = 387 Score = 106 bits (264), Expect = 5e-23 Identities = 54/108 (50%), Positives = 68/108 (62%) Frame = +3 Query: 234 LDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXXXXX 413 ++NYLD +YFG I +GTPPQ+FTVIFDTGSSNLWVPS+ C S+AC LH Sbjct: 67 MENYLDAEYFGTISIGTPPQDFTVIFDTGSSNLWVPSTYC-SSLACALHKRFNPEDSSTY 125 Query: 414 XXNGETCTISYGSGSIAGFFSEDSVLVGELVVKNQKFIETTREASPTF 557 ET +I+YG+GS+ G D+V VG + NQ F + E S TF Sbjct: 126 QGTSETLSITYGTGSMTGILGYDTVKVGSIEDTNQIFGLSKTEPSLTF 173
>CATD_BOVIN (P80209) Cathepsin D precursor (EC 3.4.23.5)| Length = 390 Score = 106 bits (264), Expect = 5e-23 Identities = 54/118 (45%), Positives = 69/118 (58%), Gaps = 10/118 (8%) Frame = +3 Query: 234 LDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKC-YFSIACYLHHXXXXXXXXX 410 L NY+D QY+GEIG+GTPPQ FTV+FDTGS+NLWVPS C IAC+ H Sbjct: 51 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSANLWVPSIHCKLLDIACWTHRKYNSDKSST 110 Query: 411 XXXNGETCTISYGSGSIAGFFSEDSVLV---------GELVVKNQKFIETTREASPTF 557 NG T I YGSGS++G+ S+D+V V G + V+ Q F E ++ F Sbjct: 111 YVKNGTTFDIHYGSGSLSGYLSQDTVSVPCNPSSSSPGGVTVQRQTFGEAIKQPGVVF 168
>PEPA4_RABIT (P28713) Pepsin II-4 precursor (EC 3.4.23.1) (Pepsin A)| Length = 387 Score = 105 bits (262), Expect = 9e-23 Identities = 54/108 (50%), Positives = 67/108 (62%) Frame = +3 Query: 234 LDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXXXXX 413 L+NYLD +YFG I +GTPPQ+FTVIFDTGSSNLWVPS+ C S+AC LH Sbjct: 67 LENYLDAEYFGTISIGTPPQDFTVIFDTGSSNLWVPSTYC-SSLACALHKRFNPEDSSTY 125 Query: 414 XXNGETCTISYGSGSIAGFFSEDSVLVGELVVKNQKFIETTREASPTF 557 ET +I+YG+GS+ G D+V VG + NQ F + E TF Sbjct: 126 QGTSETLSITYGTGSMTGILGYDTVKVGSIEDTNQIFGLSKTEPGLTF 173
>PEPC_SORUN (Q9GMY4) Gastricsin precursor (EC 3.4.23.3) (Pepsinogen C)| Length = 389 Score = 104 bits (259), Expect = 2e-22 Identities = 64/170 (37%), Positives = 88/170 (51%) Frame = +3 Query: 48 LSCALLLGGACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHSLGLSGDDI 227 L C LL A ++++ L K + +ETL L + + D ++ G Sbjct: 8 LVCLQLLEAA----VVKVPLKKFKSIRETLREQGLLGEFLRTHPYDPAQKYHFGDFSVAY 63 Query: 228 VPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXXX 407 P+ YLD YFGEI +GTPPQNF V+FDTGSSNLWVPS C S AC H Sbjct: 64 EPMA-YLDAAYFGEISIGTPPQNFLVLFDTGSSNLWVPSVYCQ-SQACTGHARFNPSKSS 121 Query: 408 XXXXNGETCTISYGSGSIAGFFSEDSVLVGELVVKNQKFIETTREASPTF 557 NG+T ++ YGSGS+ GFF D++ + + V +Q+F + E F Sbjct: 122 TYSTNGQTFSLQYGSGSLTGFFGYDTMTLQNIKVPHQEFGLSQNEPGENF 171
>PEPA_HUMAN (P00790) Pepsin A precursor (EC 3.4.23.1)| Length = 388 Score = 104 bits (259), Expect = 2e-22 Identities = 61/164 (37%), Positives = 88/164 (53%), Gaps = 3/164 (1%) Frame = +3 Query: 42 WILSCALLLGGACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHSLGLSGD 221 W+L L+ C + ++ L +K+ + TL+ L + K + ++ Sbjct: 3 WLLLLGLVALSECI--MYKVPLIRKKSLRRTLSERGLLKDFLKKHNLNPARKYFPQWEAP 60 Query: 222 DIV---PLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXX 392 +V PL+NYLD +YFG IG+GTP Q+FTV+FDTGSSNLWVPS C S+AC H+ Sbjct: 61 TLVDEQPLENYLDMEYFGTIGIGTPAQDFTVVFDTGSSNLWVPSVYC-SSLACTNHNRFN 119 Query: 393 XXXXXXXXXNGETCTISYGSGSIAGFFSEDSVLVGELVVKNQKF 524 ET +I+YG+GS+ G D+V VG + NQ F Sbjct: 120 PEDSSTYQSTSETVSITYGTGSMTGILGYDTVQVGGISDTNQIF 163
>CATE_MOUSE (P70269) Cathepsin E precursor (EC 3.4.23.34)| Length = 397 Score = 103 bits (258), Expect = 2e-22 Identities = 55/109 (50%), Positives = 63/109 (57%) Frame = +3 Query: 231 PLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXXXX 410 PL NYLD +YFG I +GTPPQNFTVIFDTGSSNLWVPS C S AC H Sbjct: 70 PLINYLDMEYFGTISIGTPPQNFTVIFDTGSSNLWVPSVYC-TSPACKAHPVFHPSQSDT 128 Query: 411 XXXNGETCTISYGSGSIAGFFSEDSVLVGELVVKNQKFIETTREASPTF 557 G +I YG+GS+ G D V V L V Q+F E+ +E TF Sbjct: 129 YTEVGNHFSIQYGTGSLTGIIGADQVSVEGLTVDGQQFGESVKEPGQTF 177
>PEPC_SUNMU (P81498) Gastricsin precursor (EC 3.4.23.3) (Pepsinogen C-1)| Length = 389 Score = 103 bits (257), Expect = 3e-22 Identities = 59/154 (38%), Positives = 79/154 (51%) Frame = +3 Query: 96 RINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHSLGLSGDDIVPLDNYLDTQYFGEIG 275 ++ L K + +E L L K D ++ G P+ Y+D YFGEI Sbjct: 20 KVTLKKFKSIRENLREQGLLEDFLKTNHYDPAQKYHFGDFSVAYEPMA-YMDASYFGEIS 78 Query: 276 VGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXXXXXXXNGETCTISYGSG 455 +GTPPQNF V+FDTGSSNLWVPS C S AC H NG+T ++ YGSG Sbjct: 79 IGTPPQNFLVLFDTGSSNLWVPSVYCQ-SQACTGHARFNPNQSSTYSTNGQTFSLQYGSG 137 Query: 456 SIAGFFSEDSVLVGELVVKNQKFIETTREASPTF 557 S+ GFF D++ V + V +Q+F + E F Sbjct: 138 SLTGFFGYDTMTVQNIKVPHQEFGLSQNEPGTNF 171
>PEPC_RABIT (Q9GMY2) Gastricsin precursor (EC 3.4.23.3) (Pepsinogen C)| Length = 388 Score = 103 bits (257), Expect = 3e-22 Identities = 63/170 (37%), Positives = 87/170 (51%) Frame = +3 Query: 48 LSCALLLGGACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHSLGLSGDDI 227 L C LL A ++++ L K + +ETL L ++ + D ++ G Sbjct: 8 LVCLHLLEAA----VIKVPLRKFKSIRETLKEKGLLKEFLNTHKYDPALKYRFGDFSVTY 63 Query: 228 VPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXXX 407 P+D YLD YFGEI +GTP QNF V+FDTGSSNLWVPS C S AC H+ Sbjct: 64 EPMD-YLDAAYFGEISIGTPSQNFLVLFDTGSSNLWVPSVYCQ-SEACTTHNRFNPSKSS 121 Query: 408 XXXXNGETCTISYGSGSIAGFFSEDSVLVGELVVKNQKFIETTREASPTF 557 +T ++ YGSGS+ GFF D+ + + V NQ+F + E F Sbjct: 122 TFYTYDQTFSLEYGSGSLTGFFGYDTFTIQNIEVPNQEFGLSETEPGTNF 171
>PEPA_CALJA (Q9N2D4) Pepsin A precursor (EC 3.4.23.1)| Length = 387 Score = 103 bits (257), Expect = 3e-22 Identities = 64/164 (39%), Positives = 89/164 (54%), Gaps = 3/164 (1%) Frame = +3 Query: 42 WILSCALLLGGACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHSLGLSGD 221 W+L +L+ A S+ L +++L KK+ ++ L L + K D S++ Sbjct: 3 WLLLLSLV---ALSECLYKVSLIKKKSLRKNLIEHGLLKDFLKNNTLDPASKYFPQGEAA 59 Query: 222 DIV---PLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXX 392 ++ PL NYLD +YFG IG+GTP Q FTVIFDTGSSNLWVPS C S AC H+ Sbjct: 60 TMIANQPLVNYLDMEYFGTIGIGTPAQEFTVIFDTGSSNLWVPSIYC-SSPACTNHNRFN 118 Query: 393 XXXXXXXXXNGETCTISYGSGSIAGFFSEDSVLVGELVVKNQKF 524 +T +I+YG+GS+ G D+V VG + NQ F Sbjct: 119 PQESSTYQATSQTLSIAYGTGSMTGILGYDTVQVGGIADTNQIF 162
>PEPC_RHIFE (Q9GMY3) Gastricsin precursor (EC 3.4.23.3) (Pepsinogen C)| Length = 389 Score = 103 bits (256), Expect = 4e-22 Identities = 62/171 (36%), Positives = 88/171 (51%) Frame = +3 Query: 45 ILSCALLLGGACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHSLGLSGDD 224 +L C LL ++++ L K + +ET+ L + K + D ++ Sbjct: 7 VLLCLQLLEAK----VVKVPLKKLKSLRETMKEKGLLEEFLKNHKYDPAQKYRYTDFSVA 62 Query: 225 IVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXX 404 P+ Y+D YFGEI +GTPPQNF V+FDTGSSNLWVPS C + AC H Sbjct: 63 YEPMA-YMDAAYFGEISIGTPPQNFLVLFDTGSSNLWVPSVYCQ-TQACTGHTRFNPSQS 120 Query: 405 XXXXXNGETCTISYGSGSIAGFFSEDSVLVGELVVKNQKFIETTREASPTF 557 NG+T ++ YGSGS+ GFF D++ V + V NQ+F + E F Sbjct: 121 STYSTNGQTFSLQYGSGSLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNF 171
>PEPA_MACMU (P11489) Pepsin A precursor (EC 3.4.23.1)| Length = 388 Score = 102 bits (254), Expect = 7e-22 Identities = 60/164 (36%), Positives = 87/164 (53%), Gaps = 3/164 (1%) Frame = +3 Query: 42 WILSCALLLGGACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHSLGLSGD 221 W+L L+ C + ++ L +K+ + L+ L + K + S++ Sbjct: 3 WLLLLGLVALSECI--IYKVPLVRKKSLRRNLSEHGLLKDFLKKHNRNPASKYFPQTEAP 60 Query: 222 DIV---PLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXX 392 ++ PL+NYLD +YFG IG+GTP Q+FTVIFDTGSSNLWVPS C S+AC H+ Sbjct: 61 TLIDEQPLENYLDVEYFGTIGIGTPAQDFTVIFDTGSSNLWVPSVYC-SSLACTNHNLFN 119 Query: 393 XXXXXXXXXNGETCTISYGSGSIAGFFSEDSVLVGELVVKNQKF 524 T +I+YG+GS+ G D+V VG + NQ F Sbjct: 120 PQDSSTYQSTSGTLSITYGTGSMTGILGYDTVQVGGISDTNQIF 163
>PEPA1_MACFU (P03954) Pepsin A-1 precursor (EC 3.4.23.1) (Pepsin III-3)| Length = 388 Score = 102 bits (253), Expect = 9e-22 Identities = 60/164 (36%), Positives = 87/164 (53%), Gaps = 3/164 (1%) Frame = +3 Query: 42 WILSCALLLGGACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHSLGLSGD 221 W+L L+ C + ++ L +K+ + L+ L + K + S++ Sbjct: 3 WLLLLGLVALSECI--IYKVPLVRKKSLRRNLSEHGLLKDFLKKHNLNPASKYFPQAEAP 60 Query: 222 DIV---PLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXX 392 ++ PL+NYLD +YFG IG+GTP Q+FTVIFDTGSSNLWVPS C S+AC H+ Sbjct: 61 TLIDEQPLENYLDVEYFGTIGIGTPAQDFTVIFDTGSSNLWVPSVYC-SSLACTNHNLFN 119 Query: 393 XXXXXXXXXNGETCTISYGSGSIAGFFSEDSVLVGELVVKNQKF 524 T +I+YG+GS+ G D+V VG + NQ F Sbjct: 120 PQDSSTYQSTSGTLSITYGTGSMTGILGYDTVQVGGISDTNQIF 163
>PAG2_BOVIN (Q28057) Pregnancy-associated glycoprotein 2 precursor (EC| 3.4.23.-) (PAG 2) Length = 376 Score = 102 bits (253), Expect = 9e-22 Identities = 64/161 (39%), Positives = 79/161 (49%) Frame = +3 Query: 42 WILSCALLLGGACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHSLGLSGD 221 W++ L+ A S+ ++ + L K + +ETL L + R S S Sbjct: 3 WLVLLGLV---ALSECIVILPLKKMKTLRETLREKNLLNN----FLEEQAYRLSKNDSKI 55 Query: 222 DIVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXX 401 I PL NYLDT Y G I +GTPPQ F V+FDTGS+NLWVP C S ACY H Sbjct: 56 TIHPLRNYLDTAYVGNITIGTPPQEFRVVFDTGSANLWVPCITC-TSPACYTHKTFNPQN 114 Query: 402 XXXXXXNGETCTISYGSGSIAGFFSEDSVLVGELVVKNQKF 524 G TI YGSG I GF D+V +G LV Q F Sbjct: 115 SSSFREVGSPITIFYGSGIIQGFLGSDTVRIGNLVSPEQSF 155
>PEPA_BOVIN (P00792) Pepsin A precursor (EC 3.4.23.1)| Length = 372 Score = 101 bits (252), Expect = 1e-21 Identities = 52/98 (53%), Positives = 62/98 (63%) Frame = +3 Query: 231 PLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXXXX 410 PL NYLDT+YFG IG+GTP Q+FTVIFDTGSSNLWVPS C S AC H+ Sbjct: 51 PLQNYLDTEYFGTIGIGTPAQDFTVIFDTGSSNLWVPSIYC-SSEACTNHNRFNPQDSST 109 Query: 411 XXXNGETCTISYGSGSIAGFFSEDSVLVGELVVKNQKF 524 ET +I+YG+GS+ G D+V VG + NQ F Sbjct: 110 YEATSETLSITYGTGSMTGILGYDTVQVGGISDTNQIF 147
>PEPA_RHIFE (Q9GMY7) Pepsin A precursor (EC 3.4.23.1)| Length = 386 Score = 100 bits (250), Expect = 2e-21 Identities = 60/162 (37%), Positives = 86/162 (53%), Gaps = 1/162 (0%) Frame = +3 Query: 42 WILSCALLLGGACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRH-SLGLSG 218 W+L +L+ C + ++ L KK+ ++ L L + K + S++ S Sbjct: 3 WLLLLSLVALSECY--IYKVPLVKKKSLRKNLMEQGLLQDYLKTHSINPASKYLKEAASM 60 Query: 219 DDIVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXX 398 PL+NY+D +YFG IG+GTPPQ FTVIFDTGSSNLWVPS C S AC H+ Sbjct: 61 MATQPLENYMDMEYFGTIGIGTPPQEFTVIFDTGSSNLWVPSVYC-SSPACSNHNRFNPQ 119 Query: 399 XXXXXXXNGETCTISYGSGSIAGFFSEDSVLVGELVVKNQKF 524 + +++YG+GS+ G D+V VG + NQ F Sbjct: 120 QSSTYQGTNQKLSVAYGTGSMTGILGYDTVQVGGITDTNQIF 161
>PEPA2_MACFU (P27677) Pepsin A-2/A-3 precursor (EC 3.4.23.1) (Pepsin| III-2/III-1) Length = 388 Score = 100 bits (250), Expect = 2e-21 Identities = 60/164 (36%), Positives = 87/164 (53%), Gaps = 3/164 (1%) Frame = +3 Query: 42 WILSCALLLGGACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHSLGLSGD 221 W+L L+ C + ++ L +K+ + L+ L + K + S++ Sbjct: 3 WLLLLGLVALSECI--IHKVPLVRKKSLRRNLSEHGLLKDFLKKHNFNPASKYFPQAEAP 60 Query: 222 DIV---PLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXX 392 ++ PL+NYLD +YFG IG+GTP Q+FTVIFDTGSSNLWVPS C S+AC H+ Sbjct: 61 TLIDEQPLENYLDMEYFGTIGIGTPAQDFTVIFDTGSSNLWVPSVYC-SSLACTNHNRFN 119 Query: 393 XXXXXXXXXNGETCTISYGSGSIAGFFSEDSVLVGELVVKNQKF 524 T +I+YG+GS+ G D+V VG + NQ F Sbjct: 120 PQDSSTYQSTSGTVSITYGTGSMTGILGYDTVQVGGISDTNQIF 163
>PEPE_CHICK (P16476) Embryonic pepsinogen precursor (EC 3.4.23.-)| Length = 383 Score = 100 bits (249), Expect = 3e-21 Identities = 66/173 (38%), Positives = 87/173 (50%), Gaps = 3/173 (1%) Frame = +3 Query: 48 LSCALLLGGACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHSLGLSGDDI 227 L CA+L A SDG+ R+ L + + +E L L + R D G++ Sbjct: 6 LLCAVL---ALSDGITRLPLERGKKLREILREKGLLHHFLQHHRYDIGTKFPHAFPDVLT 62 Query: 228 V---PLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXX 398 V PL N LD +Y+G I +GTPPQ+FTV+FDTGSSNLWVPS C S AC H Sbjct: 63 VVTEPLLNTLDMEYYGTISIGTPPQDFTVVFDTGSSNLWVPSVSC-TSPACQSHQMFNPS 121 Query: 399 XXXXXXXNGETCTISYGSGSIAGFFSEDSVLVGELVVKNQKFIETTREASPTF 557 G+ +I YG+G + G D+V V L+ NQ F +T E F Sbjct: 122 QSSTYKSTGQNLSIHYGTGDMEGTVGCDTVTVASLMDTNQLFGLSTSEPGQFF 174
>CATE_RABIT (P43159) Cathepsin E precursor (EC 3.4.23.34)| Length = 396 Score = 100 bits (249), Expect = 3e-21 Identities = 53/109 (48%), Positives = 64/109 (58%) Frame = +3 Query: 231 PLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXXXX 410 PL NYLD +YFG I +G+PPQNFTVIFDT SSNLWVPS C S AC +H Sbjct: 69 PLINYLDMEYFGTISIGSPPQNFTVIFDTVSSNLWVPSVYC-TSPACQMHPQFRPSQSNT 127 Query: 411 XXXNGETCTISYGSGSIAGFFSEDSVLVGELVVKNQKFIETTREASPTF 557 G +I+YG+GS+ G D V V L V Q+F E+ +E TF Sbjct: 128 YSEVGTPFSIAYGTGSLTGIIGADQVSVQGLTVVGQQFGESVKEPGQTF 176
>PAG2_PIG (Q29079) Pregnancy-associated glycoprotein 2 precursor (EC| 3.4.23.-) (PAG 2) Length = 420 Score = 100 bits (248), Expect = 4e-21 Identities = 62/176 (35%), Positives = 90/176 (51%), Gaps = 4/176 (2%) Frame = +3 Query: 42 WILSCALLLGGACSDGLLRINLSKKRLDKETLTAAKLARQETKL----LRSDDGSRHSLG 209 W++ L+ A SD L+ I L+K + +E+L L + K + + S++S Sbjct: 3 WLVILGLV---ALSDCLVMIPLTKVKSVRESLREKGLLKNFLKEHPYNMIQNLLSKNSSH 59 Query: 210 LSGDDIVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXX 389 + PL NYLD Y G I +GTPPQ F+V+FDTGSS+LWVPS C S AC H Sbjct: 60 VQKFSYQPLRNYLDMVYVGNISIGTPPQQFSVVFDTGSSDLWVPSIYCK-SKACVTHRSF 118 Query: 390 XXXXXXXXXXNGETCTISYGSGSIAGFFSEDSVLVGELVVKNQKFIETTREASPTF 557 G++ + YGSG ++GF +D+V +G+L Q F + E F Sbjct: 119 NPSHSSTFHDRGKSIKLEYGSGKMSGFLGQDTVRIGQLTSTGQAFGLSKEETGKAF 174
>PEPA_SUNMU (P81497) Pepsin A precursor (EC 3.4.23.1)| Length = 387 Score = 99.8 bits (247), Expect = 5e-21 Identities = 62/158 (39%), Positives = 86/158 (54%), Gaps = 3/158 (1%) Frame = +3 Query: 60 LLLG-GACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHSLGLSGDDIV-- 230 LLLG A S+ L ++ L KK+ ++ L L + + S++ + ++ Sbjct: 6 LLLGLVALSECLYKVPLVKKKSLRQNLIENGLLKDFLAKHNVNPASKYFPTEAATELADQ 65 Query: 231 PLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXXXX 410 PL NY+D +YFG IG+GTPPQ FTVIFDTGSSNLWVPS C S AC H+ Sbjct: 66 PLVNYMDMEYFGTIGIGTPPQEFTVIFDTGSSNLWVPSVYC-SSPACSNHNRFNPQKSST 124 Query: 411 XXXNGETCTISYGSGSIAGFFSEDSVLVGELVVKNQKF 524 +T +I+YG+GS+ G D+V V + NQ F Sbjct: 125 FQSTSQTLSIAYGTGSMTGVLGYDTVQVAGIADTNQIF 162
>CATE_RAT (P16228) Cathepsin E precursor (EC 3.4.23.34)| Length = 398 Score = 99.8 bits (247), Expect = 5e-21 Identities = 52/109 (47%), Positives = 63/109 (57%) Frame = +3 Query: 231 PLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXXXX 410 PL NYLD +YFG + +G+P QNFTVIFDTGSSNLWVPS C S AC H Sbjct: 71 PLINYLDMEYFGTVSIGSPSQNFTVIFDTGSSNLWVPSVYC-TSPACKAHPVFHPSQSST 129 Query: 411 XXXNGETCTISYGSGSIAGFFSEDSVLVGELVVKNQKFIETTREASPTF 557 G +I YG+GS+ G D V V L V+ Q+F E+ +E TF Sbjct: 130 YMEVGNHFSIQYGTGSLTGIIGADQVSVEGLTVEGQQFGESVKEPGQTF 178
>PEPB_CANFA (Q8SQ41) Pepsin B precursor (EC 3.4.23.2)| Length = 390 Score = 99.0 bits (245), Expect = 8e-21 Identities = 61/162 (37%), Positives = 86/162 (53%), Gaps = 3/162 (1%) Frame = +3 Query: 81 SDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHSLGLSGDDIV---PLDNYLD 251 S+G+ RI L K + ++ + + ET L + L +D V P NYLD Sbjct: 14 SEGVERIILKKGKSIRQVMEERGVL--ETFLRNHPKVDPAAKYLFNNDAVAYEPFTNYLD 71 Query: 252 TQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXXXXXXXNGET 431 + YFGEI +GTPPQNF ++FDTGSSNLWVPS+ C S AC H+ + +T Sbjct: 72 SYYFGEISIGTPPQNFLILFDTGSSNLWVPSTYCQ-SQACSNHNRFNPSRSSTYQSSEQT 130 Query: 432 CTISYGSGSIAGFFSEDSVLVGELVVKNQKFIETTREASPTF 557 T++YG GS+ D+V V +V+ NQ F + E + F Sbjct: 131 YTLAYGFGSLTVLLGYDTVTVQNIVIHNQLFGMSENEPNYPF 172
>CATE_HUMAN (P14091) Cathepsin E precursor (EC 3.4.23.34)| Length = 401 Score = 98.2 bits (243), Expect = 1e-20 Identities = 54/114 (47%), Positives = 65/114 (57%), Gaps = 5/114 (4%) Frame = +3 Query: 231 PLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXXXX 410 PL NYLD +YFG I +G+PPQNFTVIFDTGSSNLWVPS C S AC H Sbjct: 69 PLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC-TSPACKTHSRFQPSQSST 127 Query: 411 XXXNGETCTISYGSGSIAGFFSEDSV-----LVGELVVKNQKFIETTREASPTF 557 G++ +I YG+GS++G D V V L V Q+F E+ E TF Sbjct: 128 YSQPGQSFSIQYGTGSLSGIIGADQVSAFATQVEGLTVVGQQFGESVTEPGQTF 181
>PEPA_SORUN (Q9GMY8) Pepsin A precursor (EC 3.4.23.1)| Length = 387 Score = 97.1 bits (240), Expect = 3e-20 Identities = 63/166 (37%), Positives = 90/166 (54%), Gaps = 5/166 (3%) Frame = +3 Query: 42 WILSCALLLGGACSDGLL-RINLSKKRLDKETLTAAKLARQETKLLRSDDGSRH----SL 206 W+L L+ A ++GL+ ++ L KK+ +++L L K + S++ + Sbjct: 3 WLLLLGLV---ALAEGLIHKVALVKKKSLRQSLWENGLLEDFLKTHSLNPASKYFPTEAT 59 Query: 207 GLSGDDIVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHX 386 LS + PL NY+D +YFG I +GTPPQ FTVIFDTGSSNLWVPS C S AC H+ Sbjct: 60 TLSANQ--PLVNYMDMEYFGTISIGTPPQEFTVIFDTGSSNLWVPSIYC-SSPACSNHNR 116 Query: 387 XXXXXXXXXXXNGETCTISYGSGSIAGFFSEDSVLVGELVVKNQKF 524 +T +I+YG+GS+ G D+V V + NQ F Sbjct: 117 FDPQKSSTFKPTSQTVSIAYGTGSMTGVLGYDTVQVAGIADTNQIF 162
>CHYM_CALJA (Q9N2D2) Chymosin precursor (EC 3.4.23.4) (Preprorennin)| Length = 381 Score = 97.1 bits (240), Expect = 3e-20 Identities = 59/161 (36%), Positives = 84/161 (52%), Gaps = 2/161 (1%) Frame = +3 Query: 81 SDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHSLGLSGDDIVP--LDNYLDT 254 + G++RI L K + + L L K + +HS + ++ L NYLD Sbjct: 16 ASGIVRIPLHKGKSLRRALKERGLLEDFLKNHQHAVSRKHS---NSREVASEFLTNYLDC 72 Query: 255 QYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXXXXXXXNGETC 434 QYFG+I +GTPPQ FTV+FDTGSS+LWVPS C S+AC HH ++ Sbjct: 73 QYFGKIYIGTPPQEFTVVFDTGSSDLWVPSVYCN-SVACQNHHRFDPSKSSTFQNMDKSL 131 Query: 435 TISYGSGSIAGFFSEDSVLVGELVVKNQKFIETTREASPTF 557 +I YG+GS+ G D+V V +V +Q +T+E F Sbjct: 132 SIQYGTGSMQGLLGYDTVTVSSIVDPHQTVGLSTQEPGDVF 172
>PAG_HORSE (Q28389) Pregnancy-associated glycoprotein precursor (EC 3.4.23.-)| (PAG) Length = 388 Score = 95.1 bits (235), Expect = 1e-19 Identities = 66/170 (38%), Positives = 84/170 (49%) Frame = +3 Query: 15 MPFLGVTCLWILSCALLLGGACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDGS 194 M + GV L LS L+ LR NL +K + KE L R KLL Sbjct: 1 MKWFGVLGLVTLSECLVTIPLVKIKSLRENLREKDMLKEYLEKYPF-RLTHKLL------ 53 Query: 195 RHSLGLSGDDIVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACY 374 H SG P+ NYLD Y G I VGTPPQ F VIFDTGS++LWVPS C S AC Sbjct: 54 -HKHADSGVAFEPMRNYLDIAYMGIISVGTPPQEFQVIFDTGSADLWVPSIYC-SSPACS 111 Query: 375 LHHXXXXXXXXXXXXNGETCTISYGSGSIAGFFSEDSVLVGELVVKNQKF 524 H+ +G+ + YG+G ++GF D++ + LV +NQ F Sbjct: 112 NHNTFNPLRSSTFVASGQPIKLIYGTGKMSGFVGYDTIKISSLVDRNQAF 161
>PEPA_CANFA (Q9GMY6) Pepsin A precursor (EC 3.4.23.1)| Length = 386 Score = 94.4 bits (233), Expect = 2e-19 Identities = 48/97 (49%), Positives = 58/97 (59%) Frame = +3 Query: 234 LDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXXXXX 413 L NY+D +YFG IG+GTPPQ FTVIFDTGSSNLWVPS C S AC H+ Sbjct: 66 LKNYMDMEYFGTIGIGTPPQEFTVIFDTGSSNLWVPSVYC-SSPACSNHNRFNPQESSTY 124 Query: 414 XXNGETCTISYGSGSIAGFFSEDSVLVGELVVKNQKF 524 +I+YG+GS+ G D+V VG + NQ F Sbjct: 125 QGTNRPVSIAYGTGSMTGILGYDTVQVGGIADTNQIF 161
>PEPA_CHICK (P00793) Pepsin A precursor (EC 3.4.23.1)| Length = 367 Score = 93.6 bits (231), Expect = 3e-19 Identities = 47/109 (43%), Positives = 63/109 (57%) Frame = +3 Query: 198 HSLGLSGDDIVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYL 377 H + + + P+ NY+D Y+G I +GTP Q+F+VIFDTGSSNLWVPS C S AC Sbjct: 39 HPVLTATESYEPMTNYMDASYYGTISIGTPQQDFSVIFDTGSSNLWVPSIYCK-SSACSN 97 Query: 378 HHXXXXXXXXXXXXNGETCTISYGSGSIAGFFSEDSVLVGELVVKNQKF 524 H ET I+YG+GS++G D+V V + V+NQ F Sbjct: 98 HKRFDPSKSSTYVSTNETVYIAYGTGSMSGILGYDTVAVSSIDVQNQIF 146
>CHYM_BOVIN (P00794) Chymosin precursor (EC 3.4.23.4) (Preprorennin)| Length = 381 Score = 92.8 bits (229), Expect = 6e-19 Identities = 63/174 (36%), Positives = 85/174 (48%) Frame = +3 Query: 36 CLWILSCALLLGGACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHSLGLS 215 CL +L L + RI L K + ++ L L + + S++S G Sbjct: 3 CLVVLLAVFALSQGAE--ITRIPLYKGKSLRKALKEHGLLEDFLQKQQYGISSKYS-GFG 59 Query: 216 GDDIVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXX 395 VPL NYLD+QYFG+I +GTPPQ FTV+FDTGSS+ WVPS C S AC H Sbjct: 60 EVASVPLTNYLDSQYFGKIYLGTPPQEFTVLFDTGSSDFWVPSIYCK-SNACKNHQRFDP 118 Query: 396 XXXXXXXXNGETCTISYGSGSIAGFFSEDSVLVGELVVKNQKFIETTREASPTF 557 G+ +I YG+GS+ G D+V V +V Q +T+E F Sbjct: 119 RKSSTFQNLGKPLSIHYGTGSMQGILGYDTVTVSNIVDIQQTVGLSTQEPGDVF 172
>CHYM_SHEEP (P18276) Chymosin precursor (EC 3.4.23.4) (Preprorennin)| Length = 381 Score = 92.4 bits (228), Expect = 8e-19 Identities = 50/110 (45%), Positives = 63/110 (57%) Frame = +3 Query: 228 VPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXXX 407 VPL NYLD+QYFG+I +GTPPQ FTV+FDTGSS+ WVPS C S AC H Sbjct: 64 VPLTNYLDSQYFGKIYLGTPPQEFTVLFDTGSSDFWVPSIYCK-SNACKNHQRFDPRKSS 122 Query: 408 XXXXNGETCTISYGSGSIAGFFSEDSVLVGELVVKNQKFIETTREASPTF 557 G+ +I YG+GS+ G D+V V +V Q +T+E F Sbjct: 123 TFQNLGKPLSIRYGTGSMQGILGYDTVTVSNIVDIQQTVGLSTQEPGDVF 172
>PEPC_CAVPO (Q64411) Gastricsin precursor (EC 3.4.23.3) (Pepsinogen C)| Length = 394 Score = 89.7 bits (221), Expect = 5e-18 Identities = 45/112 (40%), Positives = 67/112 (59%), Gaps = 2/112 (1%) Frame = +3 Query: 195 RHSLGLSGDDIVPLD--NYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIA 368 R+ L +GD V + +Y+D YFG+I +GTPPQ+F V+FDTGSSNLWVPS C S+A Sbjct: 56 RNRLAKTGDFSVLYEPMSYMDAAYFGQISLGTPPQSFQVLFDTGSSNLWVPSVYC-SSLA 114 Query: 369 CYLHHXXXXXXXXXXXXNGETCTISYGSGSIAGFFSEDSVLVGELVVKNQKF 524 C H ++ ++ YG+GS+ G F D++ + ++ V Q+F Sbjct: 115 CTTHTRFNPRDSSTYVATDQSFSLEYGTGSLTGVFGYDTMTIQDIQVPKQEF 166
>ASP3_CAEEL (P55956) Aspartic protease 3 precursor (EC 3.4.23.-)| Length = 398 Score = 87.0 bits (214), Expect = 3e-17 Identities = 47/113 (41%), Positives = 59/113 (52%), Gaps = 5/113 (4%) Frame = +3 Query: 234 LDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYF-SIACYLHHXXXXXXXXX 410 L +Y + QY+G + +GTPPQNF V+FDTGSSNLWVP + C F IAC +H+ Sbjct: 61 LSDYSNAQYYGPVTIGTPPQNFQVLFDTGSSNLWVPCANCPFGDIACRMHNRFDCKKSSS 120 Query: 411 XXXNGETCTISYGSGSIAGFFSEDSVLVGE----LVVKNQKFIETTREASPTF 557 G + I YG+GS+ G D V G KNQ T E TF Sbjct: 121 CTATGASFEIQYGTGSMKGTVDNDVVCFGHDTTYCTDKNQGLACATSEPGITF 173
>PEP2B_GADMO (P56272) Pepsin IIB (EC 3.4.23.-)| Length = 324 Score = 86.3 bits (212), Expect = 5e-17 Identities = 44/106 (41%), Positives = 61/106 (57%) Frame = +3 Query: 234 LDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXXXXX 413 + N DT+Y+G I +GTPP++F VIFDTGSSNLWV SS C + AC H+ Sbjct: 6 MKNEADTEYYGVISIGTPPESFKVIFDTGSSNLWVSSSHC-SAQACSNHNKFKPRQSSTY 64 Query: 414 XXNGETCTISYGSGSIAGFFSEDSVLVGELVVKNQKFIETTREASP 551 G+T ++YG+G + G +D+V VG NQ+ E+ E P Sbjct: 65 VETGKTVDLTYGTGGMRGILGQDTVSVGGGSDPNQELGESQTEPGP 110
>PEPAF_RABIT (P27823) Pepsin F precursor (EC 3.4.23.1)| Length = 388 Score = 83.6 bits (205), Expect = 3e-16 Identities = 44/98 (44%), Positives = 55/98 (56%) Frame = +3 Query: 231 PLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXXXX 410 PL NYLD Y G I +GTPPQ F V+ DTGS++LWVPS C S AC H+ Sbjct: 65 PLRNYLDLAYIGIISIGTPPQEFKVVLDTGSADLWVPSIYC-SSPACGKHNTFNPLLSST 123 Query: 411 XXXNGETCTISYGSGSIAGFFSEDSVLVGELVVKNQKF 524 +G I YGSG ++GF + D+V + LV Q F Sbjct: 124 FLVSGRPINIVYGSGRMSGFLAYDTVQIAGLVDVAQAF 161
>PAG1_PIG (Q29078) Pregnancy-associated glycoprotein 1 precursor (EC| 3.4.23.-) (PAG 1) Length = 389 Score = 82.4 bits (202), Expect = 8e-16 Identities = 55/165 (33%), Positives = 82/165 (49%), Gaps = 4/165 (2%) Frame = +3 Query: 42 WILSCALLLGGACSDGLLRINLSKKRLDKETLTAAKLA----RQETKLLRSDDGSRHSLG 209 W++ L+ A S+ L+ I L+K + +E L L ++ + G + SL Sbjct: 3 WLVILGLV---ALSECLVIIPLTKVKSIRENLREKDLLLNFLKEHPYNMIQKFGLKGSLC 59 Query: 210 LSGDDIVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXX 389 + L NYLD Y G I +GTPPQ F+VIFDT SS+LWVPS++C+ S AC H Sbjct: 60 SPKISCLRLWNYLDMVYVGNITIGTPPQLFSVIFDTASSDLWVPSNQCH-SRACVTHRSF 118 Query: 390 XXXXXXXXXXNGETCTISYGSGSIAGFFSEDSVLVGELVVKNQKF 524 + T ++ SG ++G D+V +G +NQ F Sbjct: 119 NPTLSSTFQSSNRTVKLAPHSGLVSGLLGYDTVQIGRFKSENQAF 163
>PAG1_BOVIN (Q29432) Pregnancy-associated glycoprotein 1 precursor (EC| 3.4.23.-) (PAG 1) (Pregnancy-specific protein B) (PSP-B) Length = 380 Score = 81.3 bits (199), Expect = 2e-15 Identities = 52/163 (31%), Positives = 78/163 (47%), Gaps = 2/163 (1%) Frame = +3 Query: 42 WILSCALLLGGACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHSLGLSGD 221 W++ L+ A S+ +++I L + + + ++ + L+ S + G Sbjct: 3 WLVLLGLV---AFSECIVKIPLRRLKTMRNVVSGKNMLNN---FLKEHAYSLSQISFRGS 56 Query: 222 DIV--PLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXX 395 ++ PL N D Y G I +GTPPQ F V+FDT SS+LWVPS C S AC H Sbjct: 57 NLTTHPLRNIKDLVYMGNITIGTPPQEFQVVFDTASSDLWVPSDFC-TSPACSTHVRFRH 115 Query: 396 XXXXXXXXNGETCTISYGSGSIAGFFSEDSVLVGELVVKNQKF 524 +T I+YGSG + G D+V +G LV +Q F Sbjct: 116 LQSSTFRLTNKTFRITYGSGRMKGVVVHDTVRIGNLVSTDQPF 158
>PAG1_SHEEP (Q28755) Pregnancy-associated glycoprotein 1 precursor (EC| 3.4.23.-) (PAG 1) Length = 382 Score = 80.5 bits (197), Expect = 3e-15 Identities = 54/163 (33%), Positives = 81/163 (49%), Gaps = 2/163 (1%) Frame = +3 Query: 42 WILSCALLLGGACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHSLGLSGD 221 W++ L+ A S+ +++I L + + + TL+ K+ K + S+ S S Sbjct: 3 WLVLLGLV---AFSECIVKIPLRRVKTMRNTLSGKKMLNSFLKE-HAYRLSQISFRASNL 58 Query: 222 DIVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSI--ACYLHHXXXX 395 I PL N +D Y G I +GTPPQ F V+FDTGSS+L VPS C C Sbjct: 59 TIHPLRNIMDMLYVGNITIGTPPQEFQVVFDTGSSDLLVPSINCLSPTKRPCSKQDKFKH 118 Query: 396 XXXXXXXXNGETCTISYGSGSIAGFFSEDSVLVGELVVKNQKF 524 +T I +GSG++ GF + D+V +G+LV +Q F Sbjct: 119 HQSSTFRFTNDTFRIYFGSGTMRGFVAHDTVRIGDLVSTDQPF 161
>PLM2_PLAFA (P46925) Plasmepsin-2 precursor (EC 3.4.23.39) (Aspartic| hemoglobinase II) (PFAPD) Length = 453 Score = 77.4 bits (189), Expect = 3e-14 Identities = 49/136 (36%), Positives = 70/136 (51%), Gaps = 2/136 (1%) Frame = +3 Query: 156 RQETKLLRSDDGSRHSLGLSGDDIVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLW 335 ++ L S + LG S D+I +D + + ++G+ VG Q FT I DTGS+NLW Sbjct: 107 KESVNFLNSGLTKTNYLGSSNDNIELVD-FQNIMFYGDAEVGDNQQPFTFILDTGSANLW 165 Query: 336 VPSSKCYFSIACYLHHXXXXXXXXXXXXNGETCTISYGSGSIAGFFSEDSVLVGELVVKN 515 VPS KC + C H +G ++Y SG+++GFFS+D V VG L + Sbjct: 166 VPSVKC-TTAGCLTKHLYDSSKSRTYEKDGTKVEMNYVSGTVSGFFSKDLVTVGNLSLP- 223 Query: 516 QKFIET--TREASPTF 557 KFIE T PT+ Sbjct: 224 YKFIEVIDTNGFEPTY 239
>PLM1_PLAFA (P39898) Plasmepsin-1 precursor (EC 3.4.23.38) (Aspartic| hemoglobinase I) (PfAPG) Length = 452 Score = 77.0 bits (188), Expect = 3e-14 Identities = 43/127 (33%), Positives = 68/127 (53%) Frame = +3 Query: 156 RQETKLLRSDDGSRHSLGLSGDDIVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLW 335 ++ K ++ + LG +GD + L++ + Y+GE +G Q F IFDTGS+NLW Sbjct: 106 KESLKFFKTGLTQKPHLGNAGDSVT-LNDVANVMYYGEAQIGDNKQKFAFIFDTGSANLW 164 Query: 336 VPSSKCYFSIACYLHHXXXXXXXXXXXXNGETCTISYGSGSIAGFFSEDSVLVGELVVKN 515 VPS++C +I C + +G ++Y SG+++GFFS+D V + L Sbjct: 165 VPSAQCN-TIGCKTKNLYDSNKSKTYEKDGTKVEMNYVSGTVSGFFSKDIVTIANLSFP- 222 Query: 516 QKFIETT 536 KFIE T Sbjct: 223 YKFIEVT 229
>PLM1_PLAF7 (Q7KQM4) Plasmepsin-1 precursor (EC 3.4.23.38) (Aspartic| hemoglobinase I) (PfAPG) Length = 452 Score = 77.0 bits (188), Expect = 3e-14 Identities = 43/127 (33%), Positives = 68/127 (53%) Frame = +3 Query: 156 RQETKLLRSDDGSRHSLGLSGDDIVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLW 335 ++ K ++ + LG +GD + L++ + Y+GE +G Q F IFDTGS+NLW Sbjct: 106 KESLKFFKTGLTQKPHLGNAGDSVT-LNDVANVMYYGEAQIGDNKQKFAFIFDTGSANLW 164 Query: 336 VPSSKCYFSIACYLHHXXXXXXXXXXXXNGETCTISYGSGSIAGFFSEDSVLVGELVVKN 515 VPS++C +I C + +G ++Y SG+++GFFS+D V + L Sbjct: 165 VPSAQCN-TIGCKTKNLYDSNKSKTYEKDGTKVEMNYVSGTVSGFFSKDIVTIANLSFP- 222 Query: 516 QKFIETT 536 KFIE T Sbjct: 223 YKFIEVT 229
>CARP4_RHINI (Q03700) Rhizopuspepsin-4 precursor (EC 3.4.23.21) (Aspartate| protease) Length = 398 Score = 72.4 bits (176), Expect = 8e-13 Identities = 59/180 (32%), Positives = 82/180 (45%), Gaps = 8/180 (4%) Frame = +3 Query: 33 TCLWILSCALLLGGACSDGLLRINLSKKRLDKETLTAA------KLARQETKLLRSDDGS 194 +C+ + AL + A S + + LSK K A K AR + S S Sbjct: 8 SCVALACMALAVEAAPSGKKINVPLSKNANYKPNAKRAIEKANAKYARFRSSSSSSSSSS 67 Query: 195 RHSLGLSGDDIVPL-DNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIAC 371 S G VP+ D+ D +Y+GE+ VGTP + FDTGSS+LW S+ C + Sbjct: 68 CGSAGTESSGSVPVTDDGNDIEYYGEVTVGTPGIKLKLDFDTGSSDLWFASTLCTNCGSS 127 Query: 372 YLHHXXXXXXXXXXXXNGETCTISYGSGSIA-GFFSEDSVLVGELVVKNQKFIETTREAS 548 + +G T +ISYG GS A G +D+V +G L +KNQ REAS Sbjct: 128 QTKY--DPSQSSTYAKDGRTWSISYGDGSSASGILGKDTVNLGGLKIKNQIIELAKREAS 185
>CARP5_RHINI (P43232) Rhizopuspepsin-5 precursor (EC 3.4.23.21) (Aspartate| protease) Length = 392 Score = 70.9 bits (172), Expect = 2e-12 Identities = 47/126 (37%), Positives = 62/126 (49%), Gaps = 2/126 (1%) Frame = +3 Query: 177 RSDDGSRHSLGLSGDDIVPL-DNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKC 353 RS S +S G VP+ D Y D +YFG++ VGTP + FDTGSS+LW SS C Sbjct: 57 RSTSSSSNSTSTDGIGRVPVTDYYNDIEYFGQVKVGTPGVTLKLDFDTGSSDLWFASSLC 116 Query: 354 YFSIACYLHHXXXXXXXXXXXXNGETCTISYGSGSIA-GFFSEDSVLVGELVVKNQKFIE 530 + Y +G +ISYG GS A G D+V++G L ++ Q Sbjct: 117 --TNCGYSQTKYNPNQSRTYAKDGRAWSISYGDGSSASGILGTDTVVLGGLTIQRQTIEL 174 Query: 531 TTREAS 548 REAS Sbjct: 175 ARREAS 180
>CARP_RHICH (P06026) Rhizopuspepsin precursor (EC 3.4.23.21)| Length = 393 Score = 70.5 bits (171), Expect = 3e-12 Identities = 54/179 (30%), Positives = 87/179 (48%), Gaps = 7/179 (3%) Frame = +3 Query: 33 TCLWILSCALLLGGACSDGLLRINLSK----KRLDKETLTAAKLARQETKLLRSDDGSRH 200 +C+ I + A+ + A + + I L+K K K + A + K+ S G Sbjct: 8 SCIAIAALAVAVDAAPGEKKISIPLAKNPNYKPSAKNAIQKAIAKYNKHKINTSTGGIVP 67 Query: 201 SLGLSGDDIVPLDNY-LDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYL 377 G+ VP+ +Y D +Y+G++ +GTP + F + FDTGSS+LW+ S+ C C Sbjct: 68 DAGVG---TVPMTDYGNDVEYYGQVTIGTPGKKFNLDFDTGSSDLWIASTLC---TNCGS 121 Query: 378 HHXXXX-XXXXXXXXNGETCTISYGSGSIA-GFFSEDSVLVGELVVKNQKFIETTREAS 548 +G T +ISYG GS A G ++D+V +G L++K Q REA+ Sbjct: 122 RQTKYDPKQSSTYQADGRTWSISYGDGSSASGILAKDNVNLGGLLIKGQTIELAKREAA 180
>CARP3_RHINI (Q03699) Rhizopuspepsin-3 precursor (EC 3.4.23.21) (Aspartate| protease) Length = 391 Score = 69.3 bits (168), Expect = 7e-12 Identities = 45/121 (37%), Positives = 62/121 (51%), Gaps = 2/121 (1%) Frame = +3 Query: 192 SRHSLGLSGDDIVPL-DNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIA 368 S +S G VP+ D Y D +Y+GE+ VGTP + FDTGSS+LW SS C + Sbjct: 61 SSNSTSTDGIGYVPVTDYYNDIEYYGEVTVGTPGVTLKLDFDTGSSDLWFASSLCTNCGS 120 Query: 369 CYLHHXXXXXXXXXXXXNGETCTISYGSGSIA-GFFSEDSVLVGELVVKNQKFIETTREA 545 + +G T +ISYG GS A G D+V++G L +++Q REA Sbjct: 121 SQTKY--NPNESSTYARDGRTWSISYGDGSSASGILGTDTVILGGLTIRHQTIELARREA 178 Query: 546 S 548 S Sbjct: 179 S 179
>CARP1_RHINI (P10602) Rhizopuspepsin-1 precursor (EC 3.4.23.21) (Aspartate| protease) Length = 389 Score = 68.2 bits (165), Expect = 2e-11 Identities = 52/173 (30%), Positives = 80/173 (46%), Gaps = 1/173 (0%) Frame = +3 Query: 33 TCLWILSCALLLGGACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHSLGL 212 +C+ + + L + A + + I L+K K + A L + K R GS Sbjct: 8 SCVALAAMTLAVEAAPNGKKINIPLAKNNSYKPSAKNA-LNKALAKYNRRKVGSGGITTE 66 Query: 213 SGDDIVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXX 392 + + +D D +Y+GE+ VGTP + FDTGSS++W S+ C S H Sbjct: 67 ASGSVPMVDYENDVEYYGEVTVGTPGIKLKLDFDTGSSDMWFASTLC--SSCSNSHTKYD 124 Query: 393 XXXXXXXXXNGETCTISYGSGSIA-GFFSEDSVLVGELVVKNQKFIETTREAS 548 +G T +ISYG GS A G + D+V +G L++K Q RE+S Sbjct: 125 PKKSSTYAADGRTWSISYGDGSSASGILATDNVNLGGLLIKKQTIELAKRESS 177
>CARP_RHIMI (P00799) Mucorpepsin precursor (EC 3.4.23.23) (Mucor rennin)| Length = 430 Score = 67.0 bits (162), Expect = 3e-11 Identities = 48/182 (26%), Positives = 72/182 (39%), Gaps = 13/182 (7%) Frame = +3 Query: 48 LSCALLLGGACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHSL----GLS 215 ++ A+LL A +SK+ K+ L A L K ++ G + GL Sbjct: 6 ITSAILLTAASLSLTTARPVSKQSESKDKLLALPLTSVSRKFSQTKFGQQQLAEKLAGLK 65 Query: 216 GDDIVPLDNYLDT---------QYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIA 368 D +DT +Y + +GTP Q+F ++FDTGSS+ WVP C S Sbjct: 66 PFSEAAADGSVDTPGYYDFDLEEYAIPVSIGTPGQDFLLLFDTGSSDTWVPHKGCTKSEG 125 Query: 369 CYLHHXXXXXXXXXXXXNGETCTISYGSGSIAGFFSEDSVLVGELVVKNQKFIETTREAS 548 C I+YG+G G + EDS+ +G++ V Q Sbjct: 126 CVGSRFFDPSASSTFKATNYNLNITYGTGGANGLYFEDSIAIGDITVTKQILAYVDNVRG 185 Query: 549 PT 554 PT Sbjct: 186 PT 187
>CARP_RHIPU (P09177) Mucorpepsin precursor (EC 3.4.23.23) (Mucor rennin)| Length = 427 Score = 63.9 bits (154), Expect = 3e-10 Identities = 39/129 (30%), Positives = 53/129 (41%) Frame = +3 Query: 168 KLLRSDDGSRHSLGLSGDDIVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSS 347 K DGS + GL D+ +Y + +GTP Q+F ++FDTGSS+ WVP Sbjct: 64 KAFAEGDGSVDTPGLYDFDL--------EEYAIPVSIGTPGQDFYLLFDTGSSDTWVPHK 115 Query: 348 KCYFSIACYLHHXXXXXXXXXXXXNGETCTISYGSGSIAGFFSEDSVLVGELVVKNQKFI 527 C S C I+YG+G G + DS+ VG VK Q Sbjct: 116 GCDNSEGCVGKRFFDPSSSSTFKETDYNLNITYGTGGANGIYFRDSITVGGATVKQQTLA 175 Query: 528 ETTREASPT 554 + PT Sbjct: 176 YVDNVSGPT 184
>CARP2_RHINI (P43231) Rhizopuspepsin-2 precursor (EC 3.4.23.21) (Aspartate| protease) Length = 391 Score = 63.5 bits (153), Expect = 4e-10 Identities = 55/175 (31%), Positives = 80/175 (45%), Gaps = 3/175 (1%) Frame = +3 Query: 33 TCLWILSCALLLGGACSDGLLRINLSKKRLDKETL-TAAKLARQETKLLRSDDGSRHSLG 209 +C+ + AL A S L I L+K K + A + A + R+ S +S Sbjct: 8 SCVALAFMALATEAAPSGKKLSIPLTKNTNYKPSAKNAIQKALAKYHRFRTTSSS-NSTS 66 Query: 210 LSGDDIVPL-DNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHX 386 G VP+ D Y D +Y+G++ VGTP + FDTGSS+LW S+ C + + Sbjct: 67 TEGTGSVPVTDYYNDIEYYGKVTVGTPGVTLKLDFDTGSSDLWFASTLCTNCGSSQTKY- 125 Query: 387 XXXXXXXXXXXNGETCTISYGSGSIA-GFFSEDSVLVGELVVKNQKFIETTREAS 548 +G T +ISYG GS A G D+V +G L + Q REA+ Sbjct: 126 -NPNQSSTYAKDGRTWSISYGDGSSASGILGTDTVTLGGLKITKQTIELAKREAT 179
>CARP_SYNRA (P81214) Syncephapepsin precursor (EC 3.4.23.-)| Length = 395 Score = 58.2 bits (139), Expect = 2e-08 Identities = 41/114 (35%), Positives = 57/114 (50%), Gaps = 2/114 (1%) Frame = +3 Query: 213 SGDDIVPL-DNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXX 389 SG VP+ D D +Y+ + VGTP Q+ + FDTGSS+LW S+ C +C Sbjct: 73 SGTGSVPMTDVDYDVEYYATVSVGTPAQSIKLDFDTGSSDLWFSSTLC---TSCG-SKSF 128 Query: 390 XXXXXXXXXXNGETCTISYGSGSIA-GFFSEDSVLVGELVVKNQKFIETTREAS 548 G++ ISYG GS A G + D+V +G L + Q TRE+S Sbjct: 129 DPTKSSTYKKVGKSWQISYGDGSSASGITATDNVELGGLKITGQTIELATRESS 182
>CARP_CRYPA (P11838) Endothiapepsin precursor (EC 3.4.23.22) (Aspartate| protease) Length = 419 Score = 57.4 bits (137), Expect = 3e-08 Identities = 40/110 (36%), Positives = 56/110 (50%), Gaps = 1/110 (0%) Frame = +3 Query: 231 PLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXXXX 410 P+D+ LD Y + +GTP Q + FDTGSS+LWV SS+ S Sbjct: 98 PIDS-LDDAYITPVQIGTPAQTLNLDFDTGSSDLWVFSSETTASEVDGQTIYTPSKSTTA 156 Query: 411 XXXNGETCTISYGSG-SIAGFFSEDSVLVGELVVKNQKFIETTREASPTF 557 +G T +ISYG G S +G D+V VG L V Q +E+ ++ S +F Sbjct: 157 KLLSGATWSISYGDGSSSSGDVYTDTVSVGGLTVTGQA-VESAKKVSSSF 205
>CARP_IRPLA (P17576) Polyporopepsin (EC 3.4.23.29) (Aspartic proteinase)| Length = 340 Score = 54.3 bits (129), Expect = 2e-07 Identities = 30/106 (28%), Positives = 49/106 (46%) Frame = +3 Query: 228 VPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXXX 407 VP N L Y +GVG+P ++++ DTGSSN W+ + K Y Sbjct: 5 VPATNQL-VDYVVNVGVGSPATTYSLLVDTGSSNTWLGADKSYVK-------------TS 50 Query: 408 XXXXNGETCTISYGSGSIAGFFSEDSVLVGELVVKNQKFIETTREA 545 + +++YGSGS +G D+V +G L + Q +R++ Sbjct: 51 TSSATSDKVSVTYGSGSFSGTEYTDTVTLGSLTIPKQSIGVASRDS 96
>CARP4_CANAL (P43093) Candidapepsin-4 precursor (EC 3.4.23.24) (Aspartate| protease 4) (ACP 4) (Secreted aspartic protease 4) Length = 417 Score = 52.8 bits (125), Expect = 7e-07 Identities = 39/123 (31%), Positives = 55/123 (44%), Gaps = 9/123 (7%) Frame = +3 Query: 183 DDGSRHSLGLSGDDIVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYF- 359 DD R+ +G G V LDN + T Y +I +G+ Q +VI DTGSS+LWVP S Sbjct: 65 DDTGRNDVGKRGPVAVKLDNEIIT-YSADITIGSNNQKLSVIVDTGSSDLWVPDSNAVCI 123 Query: 360 -------SIACYLHHXXXXXXXXXXXXNGETCTISYGSGSIA-GFFSEDSVLVGELVVKN 515 C + I Y GS+A G +D+V +G + V++ Sbjct: 124 PKWPGDRGDFCKNNGSYSPAASSTSKNLNTPFEIKYADGSVAQGNLYQDTVGIGGVSVRD 183 Query: 516 QKF 524 Q F Sbjct: 184 QLF 186
>CARP6_CANAL (P43095) Candidapepsin-6 precursor (EC 3.4.23.24) (Aspartate| protease 6) (ACP 6) (Secreted aspartic protease 6) Length = 418 Score = 50.8 bits (120), Expect = 3e-06 Identities = 54/182 (29%), Positives = 75/182 (41%), Gaps = 20/182 (10%) Frame = +3 Query: 39 LWILSCALLLGGAC---SDGLLRINLSKKRL----DKETLTAAK----LARQETKLLRSD 185 L +L ALL+ A S G + ++ + KR D T + + L T++ D Sbjct: 7 LSVLRFALLIDAAPVKRSPGFVTLDFNVKRSLVVPDDPTAESKRSPLFLDLDPTQIPVDD 66 Query: 186 DGSRHSLGLSGDDIVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCY--- 356 G + G V LDN + T Y +I VG+ Q +VI DTGSS+LW+P SK Sbjct: 67 TGRNVGVDKRGPVAVKLDNEIIT-YSADITVGSNNQKLSVIVDTGSSDLWIPDSKAICIP 125 Query: 357 -----FSIACYLHHXXXXXXXXXXXXNGETCTISYGSGSIA-GFFSEDSVLVGELVVKNQ 518 C + I Y GS A G +D+V +G VKNQ Sbjct: 126 KWRGDCGDFCKNNGSYSPAASSTSKNLNTRFEIKYADGSYAKGNLYQDTVGIGGASVKNQ 185 Query: 519 KF 524 F Sbjct: 186 LF 187
>CARP_PODAN (O13340) Podosporapepsin precursor (EC 3.4.23.-)| Length = 425 Score = 48.9 bits (115), Expect = 1e-05 Identities = 32/94 (34%), Positives = 43/94 (45%), Gaps = 1/94 (1%) Frame = +3 Query: 240 NYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXXXXXXX 419 N +D Y + +GTPPQ + DTGSS+LWV SS + Sbjct: 102 NEVDIAYVTPVTIGTPPQTLMLDLDTGSSDLWVFSSLTPSNQVRGQEIYSPTKSSTSKLL 161 Query: 420 NGETCTISYGSGS-IAGFFSEDSVLVGELVVKNQ 518 +G T +I YG GS G D+ +G L VK+Q Sbjct: 162 SGHTWSIRYGDGSGSRGTVYTDNFTIGGLEVKSQ 195
>YPS3_YEAST (Q12303) Aspartic proteinase yapsin-3 precursor (EC 3.4.23.-)| Length = 508 Score = 48.1 bits (113), Expect = 2e-05 Identities = 33/105 (31%), Positives = 48/105 (45%), Gaps = 5/105 (4%) Frame = +3 Query: 258 YFGEIGVGTPPQNFTVIFDTGSSNLWVP---SSKCYFSIACYLHHXXXXXXXXXXXXN-G 425 Y E+ +GTP QN TV+ DTGS++LWVP + C + C + N Sbjct: 63 YSVELAIGTPSQNLTVLLDTGSADLWVPGKGNPYCGSVMDCDQYGVFDKTKSSTFKANKS 122 Query: 426 ETCTISYGSGSIA-GFFSEDSVLVGELVVKNQKFIETTREASPTF 557 +YG G+ A G F +D + EL + F E++ TF Sbjct: 123 SPFYAAYGDGTYAEGAFGQDKLKYNELDLSGLSF-AVANESNSTF 166
>CARP1_CANPA (P32951) Candidapepsin-1 precursor (EC 3.4.23.24) (Aspartate| protease 1) (ACP 1) Length = 402 Score = 48.1 bits (113), Expect = 2e-05 Identities = 29/97 (29%), Positives = 45/97 (46%), Gaps = 3/97 (3%) Frame = +3 Query: 258 YFGEIGVGTPPQNFTVIFDTGSSNLWVPSS--KCYFSIACYLHHXXXXXXXXXXXXNGET 431 Y ++ VG+ Q TVI DTGSS+ WV S +C + C G Sbjct: 76 YASKVSVGSNKQQQTVIIDTGSSDFWVVDSNAQCGKGVDCKSSGTFTPSSSSSYKNLGAA 135 Query: 432 CTISYGSGSIA-GFFSEDSVLVGELVVKNQKFIETTR 539 TI YG GS + G + +D+V + + + Q+ + T+ Sbjct: 136 FTIRYGDGSTSQGTWGKDTVTINGVSITGQQIADVTQ 172
>CARP_SACFI (P22929) Acid protease precursor (EC 3.4.23.-)| Length = 390 Score = 45.8 bits (107), Expect = 8e-05 Identities = 37/124 (29%), Positives = 55/124 (44%), Gaps = 3/124 (2%) Frame = +3 Query: 180 SDDGSRHSLGLSGDD--IVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKC 353 S G R +L + D + L+N Y I +GTP Q V DTGSS+LWVP Sbjct: 48 SSPGFRRNLRAASDAGVTISLENEYSF-YLTTIEIGTPGQKLQVDVDTGSSDLWVPGQGT 106 Query: 354 YFSIACYLHHXXXXXXXXXXXXNGETCTISYGSGSIA-GFFSEDSVLVGELVVKNQKFIE 530 Y H + +ISYG GS A G +++++V +G + +F + Sbjct: 107 SSLYGTYDH-----TKSTSYKKDRSGFSISYGDGSSARGDWAQETVSIGGASITGLEFGD 161 Query: 531 TTRE 542 T + Sbjct: 162 ATSQ 165
>PEPC_PIG (P30879) Gastricsin precursor (EC 3.4.23.3) (Pepsinogen C)| (Fragment) Length = 73 Score = 45.4 bits (106), Expect = 1e-04 Identities = 23/73 (31%), Positives = 40/73 (54%) Frame = +3 Query: 90 LLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHSLGLSGDDIVPLDNYLDTQYFGE 269 ++++ L K + ++ + L + K + D R+ +G + P+ YL+ YFGE Sbjct: 2 VIKVPLKKLKSIRQAMKEKGLLEEFLKTHKYDPAQRYRIGDISVALEPMA-YLEAAYFGE 60 Query: 270 IGVGTPPQNFTVI 308 I +GTPPQNF V+ Sbjct: 61 ISIGTPPQNFLVL 73
>PEPF_ASPFU (P41748) Aspergillopepsin F precursor (EC 3.4.23.18)| (Aspergillopepsin I) Length = 395 Score = 45.1 bits (105), Expect = 1e-04 Identities = 38/116 (32%), Positives = 53/116 (45%), Gaps = 1/116 (0%) Frame = +3 Query: 213 SGDDIVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXX 392 SG + + Y D++Y + VG N FDTGS++LWV SS+ S + H Sbjct: 72 SGSAVTTPEQY-DSEYLTPVKVGGTTLNLD--FDTGSADLWVFSSE--LSASQSSGHAIY 126 Query: 393 XXXXXXXXXNGETCTISYGSGSIA-GFFSEDSVLVGELVVKNQKFIETTREASPTF 557 NG T I YG GS A G +D+V VG + ++Q +E S F Sbjct: 127 KPSANAQKLNGYTWKIQYGDGSSASGDVYKDTVTVGGVTAQSQA-VEAASHISSQF 181
>CARP3_CANAL (P43092) Candidapepsin-3 precursor (EC 3.4.23.24) (Aspartate| protease 3) (ACP 3) (Secreted aspartic protease 3) Length = 398 Score = 44.7 bits (104), Expect = 2e-04 Identities = 28/101 (27%), Positives = 44/101 (43%), Gaps = 8/101 (7%) Frame = +3 Query: 258 YFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIA-------CYLHHXXXXXXXXXXX 416 Y +I VG+ Q TV+ DTGSS+LWVP S+ C Sbjct: 72 YASDITVGSNKQKLTVVIDTGSSDLWVPDSQVSCQAGQGQDPNFCKNEGTYSPSSSSSSQ 131 Query: 417 XNGETCTISYGSGSIA-GFFSEDSVLVGELVVKNQKFIETT 536 +I YG G+ + G + +D++ G + + Q+F + T Sbjct: 132 NLNSPFSIEYGDGTTSQGTWYKDTIGFGGISITKQQFADVT 172
>CARP_CANTR (Q00663) Candidapepsin precursor (EC 3.4.23.24) (Aspartate| protease) (ACP) Length = 394 Score = 44.3 bits (103), Expect = 2e-04 Identities = 31/102 (30%), Positives = 47/102 (46%), Gaps = 9/102 (8%) Frame = +3 Query: 258 YFGEIGVGTPPQNFTVIFDTGSSNLWV--PSSKCYFSIA------CYLHHXXXXXXXXXX 413 Y +I VG+ Q TV+ DTGSS+LWV ++C + + C Sbjct: 74 YAADIVVGSNQQKQTVVIDTGSSDLWVVDTDAECQVTYSGQTNNFCKQEGTFDPSSSSSA 133 Query: 414 XXNGETCTISYGS-GSIAGFFSEDSVLVGELVVKNQKFIETT 536 + +I YG S G F +D+V G + +KNQ+F + T Sbjct: 134 QNLNQDFSIEYGDLTSSQGSFYKDTVGFGGISIKNQQFADVT 175
>BACE2_HUMAN (Q9Y5Z0) Beta-secretase 2 precursor (EC 3.4.23.45) (Beta-site| APP-cleaving enzyme 2) (Aspartyl protease 1) (Asp 1) (ASP1) (Membrane-associated aspartic protease 1) (Memapsin-1) (Down region aspartic protease) Length = 518 Score = 43.9 bits (102), Expect = 3e-04 Identities = 25/79 (31%), Positives = 34/79 (43%) Frame = +3 Query: 258 YFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXXXXXXXNGETCT 437 Y+ E+ +GTPPQ ++ DTGSSN V + Y+ G T Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTP-----HSYIDTYFDTERSSTYRSKGFDVT 146 Query: 438 ISYGSGSIAGFFSEDSVLV 494 + Y GS GF ED V + Sbjct: 147 VKYTQGSWTGFVGEDLVTI 165
>MKC7_YEAST (P53379) Aspartic proteinase MKC7 precursor (EC 3.4.23.41) (Yapsin| 2) Length = 596 Score = 43.1 bits (100), Expect = 5e-04 Identities = 21/42 (50%), Positives = 29/42 (69%) Frame = +3 Query: 222 DIVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSS 347 ++V L N ++ Y E+ +GTPPQ TV+ DTGSS+LWV S Sbjct: 70 ELVELTNQ-NSFYSVELDIGTPPQKVTVLVDTGSSDLWVTGS 110
>YPS1_YEAST (P32329) Aspartic proteinase 3 precursor (EC 3.4.23.41) (Yapsin-1)| Length = 569 Score = 42.7 bits (99), Expect = 7e-04 Identities = 18/30 (60%), Positives = 23/30 (76%) Frame = +3 Query: 258 YFGEIGVGTPPQNFTVIFDTGSSNLWVPSS 347 Y ++ VGTPPQN TV+ DTGSS+LW+ S Sbjct: 83 YSVDLEVGTPPQNVTVLVDTGSSDLWIMGS 112
>PEP2_THUTO (P20140) Pepsin-2 precursor (EC 3.4.23.-) (Fragment)| Length = 72 Score = 42.4 bits (98), Expect = 9e-04 Identities = 17/33 (51%), Positives = 22/33 (66%) Frame = +3 Query: 219 DDIVPLDNYLDTQYFGEIGVGTPPQNFTVIFDT 317 D P+ N D Y+G + +GTPPQ+F VIFDT Sbjct: 40 DGTEPMTNDADLSYYGVVSIGTPPQSFKVIFDT 72
>CARP1_CANAL (P28872) Candidapepsin-1 precursor (EC 3.4.23.24) (Aspartate| protease 1) (ACP 1) (Secreted aspartic protease 1) Length = 391 Score = 42.0 bits (97), Expect = 0.001 Identities = 31/107 (28%), Positives = 44/107 (41%), Gaps = 9/107 (8%) Frame = +3 Query: 258 YFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKC--------YFSIACYLHHXXXXXXXXXX 413 Y +I +G+ Q F VI DTGSS+LWVP + + C Sbjct: 64 YAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGKGIYTPKSSTTS 123 Query: 414 XXNGETCTISYGSGSIA-GFFSEDSVLVGELVVKNQKFIETTREASP 551 G I YG GS + G +D+V G + Q F + T+ + P Sbjct: 124 QNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKTSIP 170
>CARP5_CANAL (P43094) Candidapepsin-5 precursor (EC 3.4.23.24) (Aspartate| protease 5) (ACP 5) (Secreted aspartic protease 5) Length = 418 Score = 41.2 bits (95), Expect = 0.002 Identities = 50/182 (27%), Positives = 73/182 (40%), Gaps = 20/182 (10%) Frame = +3 Query: 39 LWILSCALLLGGAC---SDGLLRINLSKKRL----DKETLTAAK----LARQETKLLRSD 185 L +L+ ALL+ A S G + ++ + KR D T+ A + L ++ + Sbjct: 7 LSVLAFALLIDAAPVKRSPGFVTLDFNVKRSLVDPDDPTVEAKRSPLFLEFTPSEFPVDE 66 Query: 186 DGSRHSLGLSGDDIVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYF-- 359 G + G V L N T Y +I VG+ Q VI DTGSS+LW+P S Sbjct: 67 TGRDGDVDKRGPVAVTLHNEAIT-YTADITVGSDNQKLNVIVDTGSSDLWIPDSNVICIP 125 Query: 360 ------SIACYLHHXXXXXXXXXXXXNGETCTISYGSGSIA-GFFSEDSVLVGELVVKNQ 518 C I YG GS A G +D+V +G + V++Q Sbjct: 126 KWRGDKGDFCKSAGSYSPASSRTSQNLNTRFDIKYGDGSYAKGKLYKDTVGIGGVSVRDQ 185 Query: 519 KF 524 F Sbjct: 186 LF 187
>CARP8_CANAL (O42778) Candidapepsin-8 precursor (EC 3.4.23.24) (Aspartate| protease 8) (ACP 8) (Secreted aspartic protease 8) Length = 405 Score = 41.2 bits (95), Expect = 0.002 Identities = 30/102 (29%), Positives = 43/102 (42%), Gaps = 9/102 (8%) Frame = +3 Query: 258 YFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIA--------CYLHHXXXXXXXXXX 413 Y I VG+ Q TVI DTGSS+LWV S + C Sbjct: 89 YAATITVGSNKQQQTVIVDTGSSDLWVVDSAAVCQVTYPGQSPTFCKQDGTYKPSSSTTS 148 Query: 414 XXNGETCTISYGSGSIA-GFFSEDSVLVGELVVKNQKFIETT 536 G+ +I Y GS + G +D++ +G + NQ+F + T Sbjct: 149 QNLGKAFSIRYEDGSSSQGTVYKDTIGLGGASITNQQFADVT 190
>PENP_PENJA (P00798) Penicillopepsin (EC 3.4.23.20) (Peptidase A)| Length = 323 Score = 40.0 bits (92), Expect = 0.004 Identities = 32/104 (30%), Positives = 47/104 (45%), Gaps = 1/104 (0%) Frame = +3 Query: 249 DTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXXXXXXXNGE 428 D +Y + +G N FDTGS++LWV S++ + H +G Sbjct: 14 DEEYITPVTIGGTTLNLN--FDTGSADLWVFSTE--LPASQQSGHSVYNPSATGKELSGY 69 Query: 429 TCTISYGSGSIA-GFFSEDSVLVGELVVKNQKFIETTREASPTF 557 T +ISYG GS A G DSV VG + Q ++ ++ S F Sbjct: 70 TWSISYGDGSSASGNVFTDSVTVGGVTAHGQA-VQAAQQISAQF 112
>PEPA_ASPAW (P17946) Aspergillopepsin A precursor (EC 3.4.23.18)| Length = 394 Score = 39.3 bits (90), Expect = 0.008 Identities = 34/104 (32%), Positives = 46/104 (44%), Gaps = 1/104 (0%) Frame = +3 Query: 249 DTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXXXXXXXNGE 428 D +Y + VG + FDTGS++LWV S + S H +G Sbjct: 82 DEEYLTPVTVGKSTLHLD--FDTGSADLWVFSDELPSSE--QTGHDLYTPSSSATKLSGY 137 Query: 429 TCTISYGSGSIA-GFFSEDSVLVGELVVKNQKFIETTREASPTF 557 T ISYG GS A G D+V VG V N++ +E + S F Sbjct: 138 TWDISYGDGSSASGDVYRDTVTVGG-VTTNKQAVEAASKISSEF 180
>CARP2_CANAL (P28871) Candidapepsin-2 precursor (EC 3.4.23.24) (Aspartate| protease 2) (ACP 2) (Secreted aspartic protease 2) Length = 398 Score = 38.5 bits (88), Expect = 0.013 Identities = 29/96 (30%), Positives = 38/96 (39%), Gaps = 9/96 (9%) Frame = +3 Query: 258 YFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIA--------CYLHHXXXXXXXXXX 413 Y +I VG+ Q VI DTGSS+LWVP + C Sbjct: 70 YAADITVGSNNQKLNVIVDTGSSDLWVPDVNVDCQVTYSDQTADFCKQKGTYDPSGSSAS 129 Query: 414 XXNGETCTISYGSGSIA-GFFSEDSVLVGELVVKNQ 518 I YG GS + G +D+V G + +KNQ Sbjct: 130 QDLNTPFKIGYGDGSSSQGTLYKDTVGFGGVSIKNQ 165
>BAR1_YEAST (P12630) Barrierpepsin precursor (EC 3.4.23.35) (Extracellular| "barrier" protein) (BAR proteinase) Length = 587 Score = 38.5 bits (88), Expect = 0.013 Identities = 25/77 (32%), Positives = 37/77 (48%) Frame = +3 Query: 135 LTAAKLARQETKLLRSDDGSRHSLGLSGDDIVPLDNYLDTQYFGEIGVGTPPQNFTVIFD 314 L A A T ++DG+ H L L + + Y + +GTP Q+ TV+FD Sbjct: 11 LILASFAIINTITALTNDGTGHLEFL-------LQHEEEMYYATTLDIGTPSQSLTVLFD 63 Query: 315 TGSSNLWVPSSKCYFSI 365 TGS++ WV S F + Sbjct: 64 TGSADFWVMDSSNPFCL 80
>CARP7_CANAL (P43096) Candidapepsin-7 precursor (EC 3.4.23.24) (Aspartate| protease 7) (ACP 7) (Secreted aspartic protease 7) Length = 588 Score = 38.1 bits (87), Expect = 0.017 Identities = 34/112 (30%), Positives = 49/112 (43%), Gaps = 8/112 (7%) Frame = +3 Query: 213 SGDDIVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPS---SKCYF---SIACY 374 +G + LDN T Y + VG+P Q V+ DTGSS+LW S S+C SI C Sbjct: 212 TGAFFLSLDN-TQTLYTATLKVGSPAQEVQVMIDTGSSDLWFISSGNSQCKVNGGSIDCD 270 Query: 375 LHHXXXXXXXXXXXXNGETCTISYGSGSIA-GFFSEDSVLVGE-LVVKNQKF 524 + N +ISY G A G +D++ + ++N F Sbjct: 271 KYGVFDKSKSSSWHDNKTDYSISYYDGDKASGTMGQDNITFADGFSIENANF 322
>PEPA_ASPSA (Q12567) Aspergillopepsin A precursor (EC 3.4.23.18)| (Aspergillopepsin I) Length = 394 Score = 37.7 bits (86), Expect = 0.022 Identities = 33/104 (31%), Positives = 46/104 (44%), Gaps = 1/104 (0%) Frame = +3 Query: 249 DTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXXXXXXXNGE 428 D +Y + VG + FDTGS++LWV S + S H +G Sbjct: 82 DEEYLTPVTVGKSTLHLD--FDTGSADLWVFSDELPSSE--QTGHDLYTPSSSATKLSGY 137 Query: 429 TCTISYGSGSIA-GFFSEDSVLVGELVVKNQKFIETTREASPTF 557 + ISYG GS A G D+V VG V N++ +E + S F Sbjct: 138 SWDISYGDGSSASGDVYRDTVTVGG-VTTNKQAVEAASKISSEF 180
>ASP2_BLAGE (P54958) Aspartic protease Bla g 2 precursor (EC 3.4.23.-)| (Allergen Bla g II) Length = 352 Score = 37.0 bits (84), Expect = 0.038 Identities = 24/95 (25%), Positives = 39/95 (41%) Frame = +3 Query: 243 YLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXXXXXXXN 422 +++TQY G +G QNF +FD+ S N+ V S +C + + Sbjct: 34 FINTQYAGITKIGN--QNFLTVFDSTSCNVVVASQECVGGACVCPNLQKYEKLKPKYISD 91 Query: 423 GETCTISYGSGSIAGFFSEDSVLVGELVVKNQKFI 527 G + +GS G EDS+ + L Q + Sbjct: 92 GNVQVKFFDTGSAVGRGIEDSLTISNLTTSQQDIV 126
>PEPA_ASPOR (Q06902) Aspergillopepsin A precursor (EC 3.4.23.18)| (Aspergillopepsin O) Length = 404 Score = 37.0 bits (84), Expect = 0.038 Identities = 32/104 (30%), Positives = 45/104 (43%), Gaps = 1/104 (0%) Frame = +3 Query: 249 DTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXXXXXXXNGE 428 D +Y + +G N FDTGS++LWV S + S H G Sbjct: 92 DIEYLTPVNIGGTTLNLD--FDTGSADLWVFSEELPKSE--QTGHDVYKPSGNASKIAGA 147 Query: 429 TCTISYGSGSIA-GFFSEDSVLVGELVVKNQKFIETTREASPTF 557 + ISYG GS A G +D+V VG + + Q +E + S F Sbjct: 148 SWDISYGDGSSASGDVYQDTVTVGGVTAQGQA-VEAASKISDQF 190
>CARP2_CANPA (P32950) Candidapepsin-2 precursor (EC 3.4.23.24) (Aspartate| protease 2) (ACP 2) Length = 412 Score = 37.0 bits (84), Expect = 0.038 Identities = 26/102 (25%), Positives = 42/102 (41%), Gaps = 4/102 (3%) Frame = +3 Query: 243 YLDTQYFG-EIGVGTPPQNFTVIFDTGSSNLWV--PSSKCYFSIACYLHHXXXXXXXXXX 413 Y + +G + VG+ Q V+ DTGSS+ WV S+ C Sbjct: 69 YFEGPSYGIRVSVGSNKQEQQVVLDTGSSDFWVVDSSASCQKGNCKQYGTFDPHSSTSFK 128 Query: 414 XXNGETCTISYG-SGSIAGFFSEDSVLVGELVVKNQKFIETT 536 +I YG S G + +D++ +G + NQ+F + T Sbjct: 129 SLGSSFRSIGYGDKSSSIGTWGQDTIYLGGTSITNQRFADVT 170
>NEP1_NEPGR (Q766C3) Aspartic proteinase nepenthesin-1 precursor (EC 3.4.23.-)| (Nepenthesin-I) Length = 437 Score = 37.0 bits (84), Expect = 0.038 Identities = 26/83 (31%), Positives = 35/83 (42%), Gaps = 1/83 (1%) Frame = +3 Query: 108 SKKRLDKETLTAAKLARQETKLLRSDDGSRHSLGLSGDDIVPLDNYL-DTQYFGEIGVGT 284 S K L K L + R +L R + L+G V Y D +Y + +GT Sbjct: 50 SGKNLTKFQLLERAIERGSRRLQRLE------AMLNGPSGVETSVYAGDGEYLMNLSIGT 103 Query: 285 PPQNFTVIFDTGSSNLWVPSSKC 353 P Q F+ I DTGS +W C Sbjct: 104 PAQPFSAIMDTGSDLIWTQCQPC 126
>BACE1_MOUSE (P56818) Beta-secretase 1 precursor (EC 3.4.23.46) (Beta-site APP| cleaving enzyme 1) (Beta-site amyloid precursor protein cleaving enzyme 1) (Aspartyl protease 2) (Asp 2) (ASP2) (Membrane-associated aspartic protease 2) (Memapsin-2) Length = 501 Score = 36.6 bits (83), Expect = 0.049 Identities = 21/60 (35%), Positives = 29/60 (48%), Gaps = 3/60 (5%) Frame = +3 Query: 168 KLLRSDDGSRHSLGLSGDDIVPLDNYLDTQ---YFGEIGVGTPPQNFTVIFDTGSSNLWV 338 +L R D G G + +DN Y+ E+ VG+PPQ ++ DTGSSN V Sbjct: 42 RLPRETDEESEEPGRRGSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAV 101
>BACE1_RAT (P56819) Beta-secretase 1 precursor (EC 3.4.23.46) (Beta-site APP| cleaving enzyme 1) (Beta-site amyloid precursor protein cleaving enzyme 1) (Aspartyl protease 2) (Asp 2) (ASP2) (Membrane-associated aspartic protease 2) (Memapsin-2) Length = 501 Score = 36.2 bits (82), Expect = 0.064 Identities = 21/60 (35%), Positives = 29/60 (48%), Gaps = 3/60 (5%) Frame = +3 Query: 168 KLLRSDDGSRHSLGLSGDDIVPLDNYLDTQ---YFGEIGVGTPPQNFTVIFDTGSSNLWV 338 +L R D G G + +DN Y+ E+ VG+PPQ ++ DTGSSN V Sbjct: 42 RLPRETDEEPEEPGRRGSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAV 101
>BACE1_HUMAN (P56817) Beta-secretase 1 precursor (EC 3.4.23.46) (Beta-site APP| cleaving enzyme 1) (Beta-site amyloid precursor protein cleaving enzyme 1) (Aspartyl protease 2) (Asp 2) (ASP2) (Membrane-associated aspartic protease 2) (Memapsin-2) Length = 501 Score = 36.2 bits (82), Expect = 0.064 Identities = 21/60 (35%), Positives = 29/60 (48%), Gaps = 3/60 (5%) Frame = +3 Query: 168 KLLRSDDGSRHSLGLSGDDIVPLDNYLDTQ---YFGEIGVGTPPQNFTVIFDTGSSNLWV 338 +L R D G G + +DN Y+ E+ VG+PPQ ++ DTGSSN V Sbjct: 42 RLPRETDEEPEEPGRRGSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAV 101
>NEP2_NEPGR (Q766C2) Aspartic proteinase nepenthesin-2 precursor (EC 3.4.23.-)| (Nepenthesin-II) Length = 438 Score = 36.2 bits (82), Expect = 0.064 Identities = 13/35 (37%), Positives = 19/35 (54%) Frame = +3 Query: 249 DTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKC 353 D +Y + +GTP +F+ I DTGS +W C Sbjct: 93 DGEYLMNVAIGTPDSSFSAIMDTGSDLIWTQCEPC 127
>PEPA_ASPNG (P55325) Aspergillopepsin A precursor (EC 3.4.23.18)| Length = 394 Score = 36.2 bits (82), Expect = 0.064 Identities = 33/109 (30%), Positives = 47/109 (43%), Gaps = 6/109 (5%) Frame = +3 Query: 249 DTQYFGEIGVGTPPQNFTVIFDTGSSNLW-----VPSSKCYFSIACYLHHXXXXXXXXXX 413 D +Y + VG + FDTGS++LW +PSS+ H Sbjct: 82 DEEYLTPVTVGKSTLHLD--FDTGSADLWGFSDELPSSE-------QTGHDLYTPSSSAT 132 Query: 414 XXNGETCTISYGSGSIA-GFFSEDSVLVGELVVKNQKFIETTREASPTF 557 +G + ISYG GS A G D+V VG V N++ +E + S F Sbjct: 133 KLSGYSWDISYGDGSSASGDVYRDTVTVGG-VTTNKQAVEAASKISSEF 180
>CHYM_FELCA (P09873) Chymosin precursor (EC 3.4.23.4) (Fragment)| Length = 54 Score = 34.7 bits (78), Expect = 0.19 Identities = 12/21 (57%), Positives = 19/21 (90%) Frame = +3 Query: 231 PLDNYLDTQYFGEIGVGTPPQ 293 PL ++LD++YFG+I +GTPP+ Sbjct: 34 PLADFLDSEYFGKIYIGTPPZ 54
>NEP1_NEPDI (P69476) Aspartic proteinase nepenthesin-1 (EC 3.4.23.-)| (Nepenthesin-I) (Fragments) Length = 164 Score = 33.9 bits (76), Expect = 0.32 Identities = 13/29 (44%), Positives = 18/29 (62%) Frame = +3 Query: 249 DTQYFGEIGVGTPPQNFTVIFDTGSSNLW 335 D +Y + +GTP Q F+ I DTGS +W Sbjct: 14 DGEYLMXLSIGTPAQPFSAIMDTGSDLIW 42
>PEPB_PIG (Q10735) Pepsin B precursor (EC 3.4.23.2) (Parapepsin I) (Fragment)| Length = 67 Score = 33.9 bits (76), Expect = 0.32 Identities = 13/19 (68%), Positives = 15/19 (78%) Frame = +3 Query: 231 PLDNYLDTQYFGEIGVGTP 287 P NYLD+ YFGEI +GTP Sbjct: 49 PFTNYLDSFYFGEISIGTP 67
>IRS2_HUMAN (Q9Y4H2) Insulin receptor substrate 2 (IRS-2)| Length = 1338 Score = 30.0 bits (66), Expect = 4.6 Identities = 18/74 (24%), Positives = 34/74 (45%) Frame = +3 Query: 144 AKLARQETKLLRSDDGSRHSLGLSGDDIVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGS 323 A+ + +++ +R GS+ S+ + ++P +YL+ + GTPP F+ G Sbjct: 733 AESSPEDSGYMRMWCGSKLSMEHADGKLLPNGDYLNVSPSDAVTTGTPPDFFSAALHPGG 792 Query: 324 SNLWVPSSKCYFSI 365 L CY S+ Sbjct: 793 EPLRGVPGCCYSSL 806
>VG26_BPMD2 (O64220) Minor tail protein Gp26| Length = 836 Score = 30.0 bits (66), Expect = 4.6 Identities = 21/84 (25%), Positives = 34/84 (40%) Frame = +2 Query: 140 SRKIGEAGDKIAEV*RWISPLSRPVR*RHSSPGQLPRHPVLWRDRCRHAAAELHSHI*HG 319 SR +G D + V W+ S V+ GQLP W D E ++ G Sbjct: 541 SRLVGVLADCVGAVAEWVGSWSSGVQQVSDFVGQLPGKIKSWFDDAGSWLIEAGKNVVQG 600 Query: 320 ELKPVGSIIEMLLFDSMLLAPQIQ 391 + +GS+I + + LA ++ Sbjct: 601 LINGIGSMISSAVSKAKELASSVK 624
>AXP1_YARLI (Q92389) Acid extracellular protease precursor (EC 3.4.23.-)| Length = 397 Score = 29.3 bits (64), Expect = 7.8 Identities = 22/93 (23%), Positives = 33/93 (35%), Gaps = 7/93 (7%) Frame = +3 Query: 267 EIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXX-------XXXXXXNG 425 ++ + Q + DTGS LWV + SIAC + G Sbjct: 62 QVQISLGGQTISASIDTGSEILWVWEND---SIACQVDQQDCDTDGSYNPKKSSTSKDTG 118 Query: 426 ETCTISYGSGSIAGFFSEDSVLVGELVVKNQKF 524 I+YG G G+ D+ ++G KF Sbjct: 119 VPFNINYGKGHADGYLYTDNAVIGGASAPGFKF 151 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 77,384,331 Number of Sequences: 219361 Number of extensions: 1541015 Number of successful extensions: 4240 Number of sequences better than 10.0: 132 Number of HSP's better than 10.0 without gapping: 4012 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4148 length of database: 80,573,946 effective HSP length: 106 effective length of database: 57,321,680 effective search space used: 4528412720 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
