ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | basd19l20 |
|---|---|
| Clone Library Name | barley_pub |
>KIN11_ARATH (P92958) SNF1-related protein kinase catalytic alpha subunit KIN11| (EC 2.7.11.1) (AKIN11) (AKIN alpha1) Length = 512 Score = 312 bits (800), Expect = 4e-85 Identities = 151/169 (89%), Positives = 161/169 (95%) Frame = +3 Query: 54 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 233 L NY++GKTLGIGSFGKVKIAEH+ TGHKVAIKILNRRKIKNM+MEEKV+REIKILRLFM Sbjct: 17 LPNYKLGKTLGIGSFGKVKIAEHVVTGHKVAIKILNRRKIKNMEMEEKVRREIKILRLFM 76 Query: 234 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 413 HPHIIR YEVIE +DIYVVMEYVKSGELFDYIVEKGRLQE EAR FFQQIISGV+YCHR Sbjct: 77 HPHIIRQYEVIETTSDIYVVMEYVKSGELFDYIVEKGRLQEDEARNFFQQIISGVEYCHR 136 Query: 414 NMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 NMVVHRDLKPENLLLD+ C++KIADFGLSNVMRDGHFLKTSCGSPNYAA Sbjct: 137 NMVVHRDLKPENLLLDSRCNIKIADFGLSNVMRDGHFLKTSCGSPNYAA 185
>KIN10_ARATH (Q38997) SNF1-related protein kinase catalytic alpha subunit KIN10| (EC 2.7.11.1) (AKIN10) (AKIN alpha2) Length = 535 Score = 310 bits (795), Expect = 1e-84 Identities = 149/169 (88%), Positives = 160/169 (94%) Frame = +3 Query: 54 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 233 L NY++G+TLGIGSFG+VKIAEH TGHKVAIKILNRRKIKNM+MEEKV+REIKILRLFM Sbjct: 39 LPNYKLGRTLGIGSFGRVKIAEHALTGHKVAIKILNRRKIKNMEMEEKVRREIKILRLFM 98 Query: 234 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 413 HPHIIRLYEVIE P DIY+VMEYV SGELFDYIVEKGRLQE EAR FFQQIISGV+YCHR Sbjct: 99 HPHIIRLYEVIETPTDIYLVMEYVNSGELFDYIVEKGRLQEDEARNFFQQIISGVEYCHR 158 Query: 414 NMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 NMVVHRDLKPENLLLD+ C+VKIADFGLSN+MRDGHFLKTSCGSPNYAA Sbjct: 159 NMVVHRDLKPENLLLDSKCNVKIADFGLSNIMRDGHFLKTSCGSPNYAA 207
>RKIN1_SECCE (Q02723) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 502 Score = 259 bits (662), Expect = 4e-69 Identities = 129/182 (70%), Positives = 150/182 (82%), Gaps = 3/182 (1%) Frame = +3 Query: 24 MEAGGKDGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVK 203 M+ GG+ LKNY +GK LG+G+F KV IAEH T HKVAIK+LNRR+++ +MEEK K Sbjct: 1 MDGGGEHSEALKNYYLGKILGVGTFAKVIIAEHKHTRHKVAIKVLNRRQMRAPEMEEKAK 60 Query: 204 REIKILRLFM---HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRF 374 REIKILRLF+ HPHIIR+YEVI P DI+VVMEY ++G+L DYI+EK RLQE EARR Sbjct: 61 REIKILRLFIDLIHPHIIRVYEVIVTPKDIFVVMEYCQNGDLLDYILEKRRLQEDEARRT 120 Query: 375 FQQIISGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNY 554 FQQIIS V+YCHRN VVHRDLKPENLLLD+ +VK+ADFGLSNVM DGHFLKTSCGS NY Sbjct: 121 FQQIISAVEYCHRNKVVHRDLKPENLLLDSKYNVKLADFGLSNVMHDGHFLKTSCGSLNY 180 Query: 555 AA 560 AA Sbjct: 181 AA 182
>AAPK1_RAT (P54645) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMPK alpha-1 chain) Length = 548 Score = 246 bits (629), Expect = 2e-65 Identities = 113/167 (67%), Positives = 144/167 (86%) Frame = +3 Query: 60 NYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHP 239 +Y +G TLG+G+FGKVK+ +H TGHKVA+KILNR+KI+++D+ K++REI+ L+LF HP Sbjct: 15 HYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHP 74 Query: 240 HIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNM 419 HII+LY+VI P+DI++VMEYV GELFDYI + GRL E+E+RR FQQI+SGV YCHR+M Sbjct: 75 HIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHM 134 Query: 420 VVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 VVHRDLKPEN+LLD + + KIADFGLSN+M DG FL+TSCGSPNYAA Sbjct: 135 VVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAA 181
>AAPK1_MOUSE (Q5EG47) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMPK alpha-1 chain) Length = 548 Score = 246 bits (629), Expect = 2e-65 Identities = 113/167 (67%), Positives = 144/167 (86%) Frame = +3 Query: 60 NYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHP 239 +Y +G TLG+G+FGKVK+ +H TGHKVA+KILNR+KI+++D+ K++REI+ L+LF HP Sbjct: 15 HYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHP 74 Query: 240 HIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNM 419 HII+LY+VI P+DI++VMEYV GELFDYI + GRL E+E+RR FQQI+SGV YCHR+M Sbjct: 75 HIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHM 134 Query: 420 VVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 VVHRDLKPEN+LLD + + KIADFGLSN+M DG FL+TSCGSPNYAA Sbjct: 135 VVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAA 181
>AAPK1_PONPY (Q5RDH5) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMPK alpha-1 chain) Length = 550 Score = 246 bits (629), Expect = 2e-65 Identities = 113/167 (67%), Positives = 144/167 (86%) Frame = +3 Query: 60 NYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHP 239 +Y +G TLG+G+FGKVK+ +H TGHKVA+KILNR+KI+++D+ K++REI+ L+LF HP Sbjct: 17 HYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHP 76 Query: 240 HIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNM 419 HII+LY+VI P+DI++VMEYV GELFDYI + GRL E+E+RR FQQI+SGV YCHR+M Sbjct: 77 HIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHM 136 Query: 420 VVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 VVHRDLKPEN+LLD + + KIADFGLSN+M DG FL+TSCGSPNYAA Sbjct: 137 VVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAA 183
>AAPK1_HUMAN (Q13131) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMPK alpha-1 chain) Length = 550 Score = 246 bits (629), Expect = 2e-65 Identities = 113/167 (67%), Positives = 144/167 (86%) Frame = +3 Query: 60 NYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHP 239 +Y +G TLG+G+FGKVK+ +H TGHKVA+KILNR+KI+++D+ K++REI+ L+LF HP Sbjct: 17 HYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHP 76 Query: 240 HIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNM 419 HII+LY+VI P+DI++VMEYV GELFDYI + GRL E+E+RR FQQI+SGV YCHR+M Sbjct: 77 HIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHM 136 Query: 420 VVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 VVHRDLKPEN+LLD + + KIADFGLSN+M DG FL+TSCGSPNYAA Sbjct: 137 VVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAA 183
>AAPK2_PONPY (Q5RD00) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMPK alpha-2 chain) Length = 552 Score = 246 bits (628), Expect = 3e-65 Identities = 114/167 (68%), Positives = 141/167 (84%) Frame = +3 Query: 60 NYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHP 239 +Y +G TLG+G+FGKVKI EH TGHKVA+KILNR+KI+++D+ K+KREI+ L+LF HP Sbjct: 15 HYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHP 74 Query: 240 HIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNM 419 HII+LY+VI P D ++VMEYV GELFDYI + GR++E EARR FQQI+S V YCHR+M Sbjct: 75 HIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHRHM 134 Query: 420 VVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 VVHRDLKPEN+LLD + + KIADFGLSN+M DG FL+TSCGSPNYAA Sbjct: 135 VVHRDLKPENVLLDAHMNAKIADFGLSNIMSDGEFLRTSCGSPNYAA 181
>AAPK2_HUMAN (P54646) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMPK alpha-2 chain) Length = 552 Score = 245 bits (626), Expect = 5e-65 Identities = 114/167 (68%), Positives = 141/167 (84%) Frame = +3 Query: 60 NYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHP 239 +Y +G TLG+G+FGKVKI EH TGHKVA+KILNR+KI+++D+ K+KREI+ L+LF HP Sbjct: 15 HYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHP 74 Query: 240 HIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNM 419 HII+LY+VI P D ++VMEYV GELFDYI + GR++E EARR FQQI+S V YCHR+M Sbjct: 75 HIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHRHM 134 Query: 420 VVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 VVHRDLKPEN+LLD + + KIADFGLSN+M DG FL+TSCGSPNYAA Sbjct: 135 VVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAA 181
>AAPK2_PIG (Q28948) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMPK alpha-2 chain) Length = 552 Score = 245 bits (625), Expect = 7e-65 Identities = 114/167 (68%), Positives = 140/167 (83%) Frame = +3 Query: 60 NYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHP 239 +Y +G TLG+G+FGKVKI EH TGHKVA+KILNR+KI+++D+ K+KREI+ L+LF HP Sbjct: 15 HYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHP 74 Query: 240 HIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNM 419 HII+LY+VI P D ++VMEYV GELFDYI + GR++E EARR FQQI+S V YCHR+M Sbjct: 75 HIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHRHM 134 Query: 420 VVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 VVHRDLKPEN+LLD + KIADFGLSN+M DG FL+TSCGSPNYAA Sbjct: 135 VVHRDLKPENVLLDAQMNAKIADFGLSNMMSDGEFLRTSCGSPNYAA 181
>AAPK2_RAT (Q09137) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMPK alpha-2 chain) Length = 552 Score = 244 bits (623), Expect = 1e-64 Identities = 114/167 (68%), Positives = 140/167 (83%) Frame = +3 Query: 60 NYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHP 239 +Y +G TLG+G+FGKVKI EH TGHKVA+KILNR+KI+++D+ K+KREI+ L+LF HP Sbjct: 15 HYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHP 74 Query: 240 HIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNM 419 HII+LY+VI P D ++VMEYV GELFDYI + GR++E EARR FQQI+S V YCHR+M Sbjct: 75 HIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEVEARRLFQQILSAVDYCHRHM 134 Query: 420 VVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 VVHRDLKPEN+LLD + KIADFGLSN+M DG FL+TSCGSPNYAA Sbjct: 135 VVHRDLKPENVLLDAQMNAKIADFGLSNMMSDGEFLRTSCGSPNYAA 181
>AAPK2_CAEEL (Q95ZQ4) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMP-activated kinase 2) Length = 626 Score = 242 bits (618), Expect = 5e-64 Identities = 115/167 (68%), Positives = 142/167 (85%) Frame = +3 Query: 60 NYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHP 239 +Y + +TLG+G+FGKVK+ H T +KVA+KILNR+KIK++D+ K++REI+ L LF HP Sbjct: 86 HYILKETLGVGTFGKVKVGIHETTQYKVAVKILNRQKIKSLDVVGKIRREIQNLSLFRHP 145 Query: 240 HIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNM 419 HIIRLY+VI P+DI+++ME+V GELFDYIV+ GRL+ EARRFFQQIISGV YCHR+M Sbjct: 146 HIIRLYQVISTPSDIFMIMEHVSGGELFDYIVKHGRLKTAEARRFFQQIISGVDYCHRHM 205 Query: 420 VVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 VVHRDLKPENLLLD +VKIADFGLSN+M DG FL+TSCGSPNYAA Sbjct: 206 VVHRDLKPENLLLDEQNNVKIADFGLSNIMTDGDFLRTSCGSPNYAA 252
>SNF1_CANGA (Q00372) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 612 Score = 234 bits (597), Expect = 1e-61 Identities = 111/173 (64%), Positives = 143/173 (82%) Frame = +3 Query: 42 DGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKIL 221 DG+ + NY+I KTLG GSFGKVK+A H+ TG KVA+KI+N++ + DM+ +++REI L Sbjct: 32 DGSRVGNYQIVKTLGEGSFGKVKLAYHVTTGQKVALKIINKKVLAKSDMQGRIEREISYL 91 Query: 222 RLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQ 401 RL HPHII+LY+VI++ +I +V+EY ELFDYIV++ ++ EQEARRFFQQIIS V+ Sbjct: 92 RLLRHPHIIKLYDVIKSKDEIIMVIEYA-GNELFDYIVQRNKMSEQEARRFFQQIISAVE 150 Query: 402 YCHRNMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 YCHR+ +VHRDLKPENLLLD + +VKIADFGLSN+M DG+FLKTSCGSPNYAA Sbjct: 151 YCHRHKIVHRDLKPENLLLDEHLNVKIADFGLSNIMTDGNFLKTSCGSPNYAA 203
>SNF1_YEAST (P06782) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 633 Score = 231 bits (590), Expect = 8e-61 Identities = 111/173 (64%), Positives = 141/173 (81%) Frame = +3 Query: 42 DGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKIL 221 DG + NY+I KTLG GSFGKVK+A H TG KVA+KI+N++ + DM+ +++REI L Sbjct: 48 DGAHIGNYQIVKTLGEGSFGKVKLAYHTTTGQKVALKIINKKVLAKSDMQGRIEREISYL 107 Query: 222 RLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQ 401 RL HPHII+LY+VI++ +I +V+EY ELFDYIV++ ++ EQEARRFFQQIIS V+ Sbjct: 108 RLLRHPHIIKLYDVIKSKDEIIMVIEYA-GNELFDYIVQRDKMSEQEARRFFQQIISAVE 166 Query: 402 YCHRNMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 YCHR+ +VHRDLKPENLLLD + +VKIADFGLSN+M DG+FLKTSCGSPNYAA Sbjct: 167 YCHRHKIVHRDLKPENLLLDEHLNVKIADFGLSNIMTDGNFLKTSCGSPNYAA 219
>SNF1_CANTR (O94168) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 619 Score = 229 bits (583), Expect = 5e-60 Identities = 109/171 (63%), Positives = 141/171 (82%) Frame = +3 Query: 48 NPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRL 227 N + Y+I KTLG GSFGKVK+A+H+ TG KVA+KI+NR+ + DM+ +V+REI LRL Sbjct: 47 NRIGRYQIIKTLGEGSFGKVKLAQHVGTGQKVALKIINRKTLAKSDMQGRVEREISYLRL 106 Query: 228 FMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYC 407 HPHII+LY+VI++ +I +V+E+ ELFDYIV++G++ E EARRFFQQII+ V+YC Sbjct: 107 LRHPHIIKLYDVIKSKDEIIMVIEFAGK-ELFDYIVQRGKMPEDEARRFFQQIIAAVEYC 165 Query: 408 HRNMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 HR+ +VHRDLKPENLLLD+ +VKIADFGLSN+M DG+FLKTSCGSPNYAA Sbjct: 166 HRHKIVHRDLKPENLLLDDQLNVKIADFGLSNIMTDGNFLKTSCGSPNYAA 216
>SNF1_SCHPO (O74536) SNF1-like protein kinase ssp2 (EC 2.7.11.1)| Length = 576 Score = 227 bits (578), Expect = 2e-59 Identities = 110/166 (66%), Positives = 133/166 (80%) Frame = +3 Query: 63 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 242 Y I +TLG GSFGKVK+A H KT KVA+K ++R+ +K DM +V+REI L+L HPH Sbjct: 34 YIIRETLGEGSFGKVKLATHYKTQQKVALKFISRQLLKKSDMHMRVEREISYLKLLRHPH 93 Query: 243 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 422 II+LY+VI P DI +V+EY GELFDYIVEK R+ E E RRFFQQII ++YCHR+ + Sbjct: 94 IIKLYDVITTPTDIVMVIEYA-GGELFDYIVEKKRMTEDEGRRFFQQIICAIEYCHRHKI 152 Query: 423 VHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 VHRDLKPENLLLD+N +VKIADFGLSN+M DG+FLKTSCGSPNYAA Sbjct: 153 VHRDLKPENLLLDDNLNVKIADFGLSNIMTDGNFLKTSCGSPNYAA 198
>SNF1_CANAL (P52497) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 620 Score = 226 bits (575), Expect = 4e-59 Identities = 107/177 (60%), Positives = 141/177 (79%) Frame = +3 Query: 24 MEAGGKDGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVK 203 ++ N + Y+I KTLG GSFGKVK+A+H+ TG KVA+KI+NR+ + DM+ +V+ Sbjct: 40 IDPAANPANRIGRYQILKTLGEGSFGKVKLAQHLGTGQKVALKIINRKTLAKSDMQGRVE 99 Query: 204 REIKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQ 383 REI LRL HPHII+LY+VI++ +I +V+E+ ELFDYIV++G++ E EARRFFQQ Sbjct: 100 REISYLRLLRHPHIIKLYDVIKSKDEIIMVIEFAGK-ELFDYIVQRGKMPEDEARRFFQQ 158 Query: 384 IISGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNY 554 II+ V+YCHR+ +VHRDLKPENLLLD+ +VKIADFGLSN+M DG+FLKTSCGSPNY Sbjct: 159 IIAAVEYCHRHKIVHRDLKPENLLLDDQLNVKIADFGLSNIMTDGNFLKTSCGSPNY 215
>AAPK1_CAEEL (P45894) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMP-activated kinase 1) Length = 589 Score = 207 bits (528), Expect = 1e-53 Identities = 101/167 (60%), Positives = 124/167 (74%) Frame = +3 Query: 60 NYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHP 239 N+ I +T+G G+FG VK HI+TG+ VAIKILNR ++K + K + EI L+ HP Sbjct: 23 NFVIKETIGKGAFGAVKRGTHIQTGYDVAIKILNRGRMKGLGTVNKTRNEIDNLQKLTHP 82 Query: 240 HIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNM 419 HI RL+ VI P+DI++VME V GELF YI KG L +E+RR+FQQIISGV YCH +M Sbjct: 83 HITRLFRVISTPSDIFLVMELVSGGELFSYITRKGALPIRESRRYFQQIISGVSYCHNHM 142 Query: 420 VVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 +VHRDLKPENLLLD N ++KIADFGLSN M DG L T+CGSPNYAA Sbjct: 143 IVHRDLKPENLLLDANKNIKIADFGLSNYMTDGDLLSTACGSPNYAA 189
>MARK2_RAT (O08679) Serine/threonine-protein kinase MARK2 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 2) (ELKL Motif Kinase) (EMK1) Length = 722 Score = 189 bits (481), Expect = 4e-48 Identities = 92/183 (50%), Positives = 133/183 (72%), Gaps = 1/183 (0%) Frame = +3 Query: 15 RWKMEAGGKDGNP-LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDME 191 R + A D P + NYR+ KT+G G+F KVK+A HI TG +VA+KI+++ ++ + ++ Sbjct: 36 RGRNSATSADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQ 95 Query: 192 EKVKREIKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARR 371 K+ RE++I+++ HP+I++L+EVIE +Y+VMEY GE+FDY+V GR++E+EAR Sbjct: 96 -KLFREVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARA 154 Query: 372 FFQQIISGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPN 551 F+QI+S VQYCH+ +VHRDLK ENLLLD + ++KIADFG SN G+ L T CGSP Sbjct: 155 KFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPP 214 Query: 552 YAA 560 YAA Sbjct: 215 YAA 217
>MARK2_HUMAN (Q7KZI7) Serine/threonine-protein kinase MARK2 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 2) (ELKL motif kinase) (EMK1) (PAR1 homolog) Length = 788 Score = 189 bits (481), Expect = 4e-48 Identities = 92/183 (50%), Positives = 133/183 (72%), Gaps = 1/183 (0%) Frame = +3 Query: 15 RWKMEAGGKDGNP-LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDME 191 R + A D P + NYR+ KT+G G+F KVK+A HI TG +VA+KI+++ ++ + ++ Sbjct: 36 RGRNSATSADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQ 95 Query: 192 EKVKREIKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARR 371 K+ RE++I+++ HP+I++L+EVIE +Y+VMEY GE+FDY+V GR++E+EAR Sbjct: 96 -KLFREVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARA 154 Query: 372 FFQQIISGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPN 551 F+QI+S VQYCH+ +VHRDLK ENLLLD + ++KIADFG SN G+ L T CGSP Sbjct: 155 KFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPP 214 Query: 552 YAA 560 YAA Sbjct: 215 YAA 217
>MARK1_HUMAN (Q9P0L2) Serine/threonine-protein kinase MARK1 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 1) Length = 795 Score = 189 bits (479), Expect = 6e-48 Identities = 87/167 (52%), Positives = 126/167 (75%) Frame = +3 Query: 60 NYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHP 239 NYR+ KT+G G+F KVK+A H+ TG +VA+KI+++ ++ ++ K+ RE++I+++ HP Sbjct: 59 NYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQ-KLFREVRIMKILNHP 117 Query: 240 HIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNM 419 +I++L+EVIE +Y+VMEY GE+FDY+V GR++E+EAR F+QI+S VQYCH+ Sbjct: 118 NIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKY 177 Query: 420 VVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 +VHRDLK ENLLLD + ++KIADFG SN G+ L T CGSP YAA Sbjct: 178 IVHRDLKAENLLLDGDMNIKIADFGFSNEFTVGNKLDTFCGSPPYAA 224
>MARK1_MOUSE (Q8VHJ5) Serine/threonine-protein kinase MARK1 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 1) (ELKL motif serine/threonine-protein kinase 3) Length = 795 Score = 188 bits (477), Expect = 1e-47 Identities = 87/167 (52%), Positives = 126/167 (75%) Frame = +3 Query: 60 NYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHP 239 NYR+ KT+G G+F KVK+A H+ TG +VA+KI+++ ++ ++ K+ RE++I+++ HP Sbjct: 59 NYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQ-KLFREVRIMKILNHP 117 Query: 240 HIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNM 419 +I++L+EVIE +Y+VMEY GE+FDY+V GR++E+EAR F+QI+S VQYCH+ Sbjct: 118 NIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKC 177 Query: 420 VVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 +VHRDLK ENLLLD + ++KIADFG SN G+ L T CGSP YAA Sbjct: 178 IVHRDLKAENLLLDADMNIKIADFGFSNEFTVGNKLDTFCGSPPYAA 224
>CPK24_ARATH (Q9LDI3) CBL-interacting serine/threonine-protein kinase 24 (EC| 2.7.11.1) (SNF1-related kinase 3.11) (SALT OVERLY SENSITIVE 2 protein) Length = 446 Score = 188 bits (477), Expect = 1e-47 Identities = 87/167 (52%), Positives = 125/167 (74%), Gaps = 1/167 (0%) Frame = +3 Query: 63 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 242 Y +G+T+G G+F KVK A + TG VAIKI+ + I M +++KREI I+++ HP+ Sbjct: 11 YEVGRTIGEGTFAKVKFARNTDTGDNVAIKIMAKSTILKNRMVDQIKREISIMKIVRHPN 70 Query: 243 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 422 I+RLYEV+ +P+ IY+V+E+V GELFD IV KGRL+E E+R++FQQ++ V +CH V Sbjct: 71 IVRLYEVLASPSKIYIVLEFVTGGELFDRIVHKGRLEESESRKYFQQLVDAVAHCHCKGV 130 Query: 423 VHRDLKPENLLLDNNCDVKIADFGLSNVMRDG-HFLKTSCGSPNYAA 560 HRDLKPENLLLD N ++K++DFGLS + ++G L+T+CG+PNY A Sbjct: 131 YHRDLKPENLLLDTNGNLKVSDFGLSALPQEGVELLRTTCGTPNYVA 177
>MARK1_RAT (O08678) Serine/threonine-protein kinase MARK1 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 1) Length = 793 Score = 188 bits (477), Expect = 1e-47 Identities = 87/167 (52%), Positives = 126/167 (75%) Frame = +3 Query: 60 NYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHP 239 NYR+ KT+G G+F KVK+A H+ TG +VA+KI+++ ++ ++ K+ RE++I+++ HP Sbjct: 59 NYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQ-KLFREVRIMKILNHP 117 Query: 240 HIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNM 419 +I++L+EVIE +Y+VMEY GE+FDY+V GR++E+EAR F+QI+S VQYCH+ Sbjct: 118 NIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKC 177 Query: 420 VVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 +VHRDLK ENLLLD + ++KIADFG SN G+ L T CGSP YAA Sbjct: 178 IVHRDLKAENLLLDADMNIKIADFGFSNEFTVGNKLDTFCGSPPYAA 224
>MARK3_MOUSE (Q03141) MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1)| (MPK-10) (ELKL motif kinase 2) Length = 753 Score = 187 bits (474), Expect = 2e-47 Identities = 88/167 (52%), Positives = 125/167 (74%) Frame = +3 Query: 60 NYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHP 239 NYR+ KT+G G+F KVK+A HI TG +VAIKI+++ ++ ++ K+ RE++I+++ HP Sbjct: 55 NYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQ-KLFREVRIMKILNHP 113 Query: 240 HIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNM 419 +I++L+EVIE +Y++MEY GE+FDY+V GR++E+EAR F+QI+S VQYCH+ Sbjct: 114 NIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKR 173 Query: 420 VVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 +VHRDLK ENLLLD + ++KIADFG SN G L T CGSP YAA Sbjct: 174 IVHRDLKAENLLLDADMNIKIADFGFSNEFTVGSKLDTFCGSPPYAA 220
>MARK2_MOUSE (Q05512) Serine/threonine-protein kinase MARK2 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 2) (ELKL Motif Kinase) (EMK1) Length = 776 Score = 186 bits (473), Expect = 3e-47 Identities = 91/183 (49%), Positives = 132/183 (72%), Gaps = 1/183 (0%) Frame = +3 Query: 15 RWKMEAGGKDGNP-LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDME 191 R + A D P + NYR+ KT+G G+F KVK+A HI TG +VA+KI+++ ++ + ++ Sbjct: 36 RGRNSATSADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQ 95 Query: 192 EKVKREIKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARR 371 K+ RE++I+++ HP+I++L+EVIE +Y+VMEY GE+FDY+V GR++E+EAR Sbjct: 96 -KLFREVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARA 154 Query: 372 FFQQIISGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPN 551 F+QI+ VQYCH+ +VHRDLK ENLLLD + ++KIADFG SN G+ L T CGSP Sbjct: 155 KFRQIVLHVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPP 214 Query: 552 YAA 560 YAA Sbjct: 215 YAA 217
>MARK3_RAT (Q8VHF0) MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1)| Length = 797 Score = 185 bits (470), Expect = 7e-47 Identities = 87/167 (52%), Positives = 124/167 (74%) Frame = +3 Query: 60 NYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHP 239 NYR+ KT+G G+F KVK+A HI TG +VAIKI+++ ++ ++ K+ RE++I+++ HP Sbjct: 55 NYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQ-KLFREVRIMKILNHP 113 Query: 240 HIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNM 419 +I++L+EVIE +Y++MEY GE+FDY+V GR++E+EAR F+QI+S VQYCH+ Sbjct: 114 NIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKR 173 Query: 420 VVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 +VHRDLK ENLLLD + ++KI DFG SN G L T CGSP YAA Sbjct: 174 IVHRDLKAENLLLDADMNIKITDFGFSNEFTVGSKLDTFCGSPPYAA 220
>BRSK1_HUMAN (Q8TDC3) BR serine/threonine-protein kinase 1 (EC 2.7.11.1) (SAD1| kinase) (SAD1A) Length = 794 Score = 183 bits (464), Expect = 3e-46 Identities = 90/183 (49%), Positives = 127/183 (69%) Frame = +3 Query: 9 GARWKMEAGGKDGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDM 188 G + E G+ + YR+ KTLG G G VK+ H TG KVAIKI+NR K+ + Sbjct: 32 GEEEEAEERGRHAQYVGPYRLEKTLGKGQTGLVKLGVHCITGQKVAIKIVNREKLSESVL 91 Query: 189 EEKVKREIKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEAR 368 KV+REI IL+L HPH+++L++V E +Y+V+E+V GELFDY+V+KGRL +EAR Sbjct: 92 M-KVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEAR 150 Query: 369 RFFQQIISGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSP 548 +FF+QI+S + +CH + HRDLKPENLLLD +++IADFG++++ L+TSCGSP Sbjct: 151 KFFRQIVSALDFCHSYSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSP 210 Query: 549 NYA 557 +YA Sbjct: 211 HYA 213
>NUAK1_HUMAN (O60285) NUAK family, SNF1-like kinase 1 (EC 2.7.11.1)| (AMPK-related protein kinase 5) Length = 661 Score = 182 bits (462), Expect = 6e-46 Identities = 89/166 (53%), Positives = 118/166 (71%) Frame = +3 Query: 63 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 242 Y + +TLG G++GKVK A +G VAIK + + KIK+ ++REI+I+ HPH Sbjct: 55 YELQETLGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDEQDMVHIRREIEIMSSLNHPH 114 Query: 243 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 422 II +YEV E I ++MEY GEL+DYI E+ RL E+E R FF+QI+S V YCH+N V Sbjct: 115 IISIYEVFENKDKIVIIMEYASKGELYDYISERRRLSERETRHFFRQIVSAVHYCHKNGV 174 Query: 423 VHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 VHRDLK EN+LLD+NC++KIADFGLSN+ + FL+T CGSP YA+ Sbjct: 175 VHRDLKLENILLDDNCNIKIADFGLSNLYQKDKFLQTFCGSPLYAS 220
>MARK4_MOUSE (Q8CIP4) MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1)| Length = 752 Score = 182 bits (462), Expect = 6e-46 Identities = 88/167 (52%), Positives = 123/167 (73%) Frame = +3 Query: 60 NYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHP 239 NYR+ +T+G G+F KVK+A HI TG +VAIKI+++ ++ N +K+ RE++I++ HP Sbjct: 58 NYRLLRTIGKGNFAKVKLARHILTGREVAIKIIDKTQL-NPSSLQKLFREVRIMKGLNHP 116 Query: 240 HIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNM 419 +I++L+EVIE +Y+VMEY +GE+FDY+V GR++E+EAR F+QI+S V YCH+ Sbjct: 117 NIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKN 176 Query: 420 VVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 +VHRDLK ENLLLD ++KIADFG SN G L T CGSP YAA Sbjct: 177 IVHRDLKAENLLLDAEANIKIADFGFSNEFTLGSKLDTFCGSPPYAA 223
>MARK4_HUMAN (Q96L34) MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase-like 1) Length = 752 Score = 182 bits (462), Expect = 6e-46 Identities = 88/167 (52%), Positives = 123/167 (73%) Frame = +3 Query: 60 NYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHP 239 NYR+ +T+G G+F KVK+A HI TG +VAIKI+++ ++ N +K+ RE++I++ HP Sbjct: 58 NYRLLRTIGKGNFAKVKLARHILTGREVAIKIIDKTQL-NPSSLQKLFREVRIMKGLNHP 116 Query: 240 HIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNM 419 +I++L+EVIE +Y+VMEY +GE+FDY+V GR++E+EAR F+QI+S V YCH+ Sbjct: 117 NIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKN 176 Query: 420 VVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 +VHRDLK ENLLLD ++KIADFG SN G L T CGSP YAA Sbjct: 177 IVHRDLKAENLLLDAEANIKIADFGFSNEFTLGSKLDTFCGSPPYAA 223
>BRSK2_HUMAN (Q8IWQ3) BR serine/threonine-protein kinase 2 (EC 2.7.11.1)| (Serine/threonine-protein kinase 29) (SAD1B) Length = 736 Score = 182 bits (461), Expect = 7e-46 Identities = 92/183 (50%), Positives = 128/183 (69%), Gaps = 5/183 (2%) Frame = +3 Query: 24 MEAGGKDGNP-----LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDM 188 M + GKDG + YR+ KTLG G G VK+ H T KVAIKI+NR K+ + Sbjct: 1 MTSTGKDGGAQHAQYVGPYRLEKTLGKGQTGLVKLGVHCVTCQKVAIKIVNREKLSESVL 60 Query: 189 EEKVKREIKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEAR 368 KV+REI IL+L HPH+++L++V E +Y+V+E+V GELFDY+V+KGRL +EAR Sbjct: 61 M-KVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEAR 119 Query: 369 RFFQQIISGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSP 548 +FF+QIIS + +CH + + HRDLKPENLLLD +++IADFG++++ L+TSCGSP Sbjct: 120 KFFRQIISALDFCHSHSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSP 179 Query: 549 NYA 557 +YA Sbjct: 180 HYA 182
>NUAK1_MOUSE (Q641K5) NUAK family, SNF1-like kinase 1 (EC 2.7.11.1)| Length = 658 Score = 181 bits (459), Expect = 1e-45 Identities = 91/167 (54%), Positives = 121/167 (72%), Gaps = 1/167 (0%) Frame = +3 Query: 63 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKN-MDMEEKVKREIKILRLFMHP 239 Y + +TLG G++GKVK A +G VAIK + + KIK+ +DM ++REI+I+ HP Sbjct: 56 YELQETLGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDELDMVH-IRREIEIMSSLNHP 114 Query: 240 HIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNM 419 HII +YEV E I ++MEY GEL+DYI E+ RL E+E R FF+QI+S V YCH+N Sbjct: 115 HIISIYEVFENKDKIVIIMEYASKGELYDYISERRRLSERETRHFFRQIVSAVHYCHKNG 174 Query: 420 VVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 VVHRDLK EN+LLD+NC++KIADFGLSN+ + FL+T CGSP YA+ Sbjct: 175 VVHRDLKLENILLDDNCNIKIADFGLSNLYQKDKFLQTFCGSPLYAS 221
>SN1L2_MOUSE (Q8CFH6) Serine/threonine-protein kinase SNF1-like kinase 2 (EC| 2.7.11.1) (Salt-inducible kinase 2) Length = 931 Score = 180 bits (457), Expect = 2e-45 Identities = 88/166 (53%), Positives = 118/166 (71%) Frame = +3 Query: 63 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 242 Y I TLG G+F VK+ H T +VAIKI+++ ++ +++E K+ RE++I+++ HPH Sbjct: 20 YDIEGTLGKGNFAVVKLGRHRTTKTEVAIKIIDKSQLDAVNLE-KIYREVQIMKMLDHPH 78 Query: 243 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 422 II+LY+V+E + +Y+V EY K+GE+FDY+ GRL E EARR F QI+S V YCH V Sbjct: 79 IIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGRKV 138 Query: 423 VHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 VHRDLK ENLLLDNN ++KIADFG N + G L T CGSP YAA Sbjct: 139 VHRDLKAENLLLDNNMNIKIADFGFGNFFKTGELLATWCGSPPYAA 184
>SN1L2_HUMAN (Q9H0K1) Serine/threonine-protein kinase SNF1-like kinase 2 (EC| 2.7.11.1) (Qin-induced kinase) Length = 926 Score = 179 bits (455), Expect = 4e-45 Identities = 87/166 (52%), Positives = 118/166 (71%) Frame = +3 Query: 63 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 242 Y I TLG G+F VK+ H T +VAIKI+++ ++ +++E K+ RE++I+++ HPH Sbjct: 20 YDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKSQLDAVNLE-KIYREVQIMKMLDHPH 78 Query: 243 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 422 II+LY+V+E + +Y+V EY K+GE+FDY+ GRL E EARR F QI+S V YCH + Sbjct: 79 IIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGRKI 138 Query: 423 VHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 VHRDLK ENLLLDNN ++KIADFG N + G L T CGSP YAA Sbjct: 139 VHRDLKAENLLLDNNMNIKIADFGFGNFFKSGELLATWCGSPPYAA 184
>SN1L1_HUMAN (P57059) Serine/threonine-protein kinase SNF1-like kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase SNF1LK) Length = 783 Score = 177 bits (450), Expect = 1e-44 Identities = 84/166 (50%), Positives = 119/166 (71%) Frame = +3 Query: 63 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 242 Y I +TLG G+F VK+A H T +VAIKI+++ ++ + ++E K+ RE+++++L HPH Sbjct: 27 YDIERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTRLDSSNLE-KIYREVQLMKLLNHPH 85 Query: 243 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 422 II+LY+V+E +Y+V E+ K+GE+FDY+ G L E EAR+ F QI+S V+YCH + + Sbjct: 86 IIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQILSAVEYCHDHHI 145 Query: 423 VHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 VHRDLK ENLLLD N D+K+ADFG N + G L T CGSP YAA Sbjct: 146 VHRDLKTENLLLDGNMDIKLADFGFGNFYKSGEPLSTWCGSPPYAA 191
>CIPK1_ARATH (Q8RWC9) CBL-interacting serine/threonine-protein kinase 1 (EC| 2.7.11.1) (SOS2-like protein kinase PKS13) (SNF1-related kinase 3.16) Length = 444 Score = 177 bits (450), Expect = 1e-44 Identities = 88/185 (47%), Positives = 122/185 (65%), Gaps = 3/185 (1%) Frame = +3 Query: 15 RWKMEAGGKDGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEE 194 R + E + G L Y +G+TLG G+FGKVK A+ +GH A+KI+++ +I +++ Sbjct: 4 RQEEEKKAEKGMRLGKYELGRTLGEGNFGKVKFAKDTVSGHSFAVKIIDKSRIADLNFSL 63 Query: 195 KVKREIKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRF 374 ++KREI+ L++ HPHI+RL+EV+ + I +VME V GELFD IV G+L E + R+ Sbjct: 64 QIKREIRTLKMLKHPHIVRLHEVLASKTKINMVMELVTGGELFDRIVSNGKLTETDGRKM 123 Query: 375 FQQIISGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLSNV---MRDGHFLKTSCGS 545 FQQ+I G+ YCH V HRDLK EN+LLD +KI DFGLS + RD L T+CGS Sbjct: 124 FQQLIDGISYCHSKGVFHRDLKLENVLLDAKGHIKITDFGLSALPQHFRDDGLLHTTCGS 183 Query: 546 PNYAA 560 PNY A Sbjct: 184 PNYVA 188
>SN1L1_RAT (Q9R1U5) Serine/threonine-protein kinase SNF1-like kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase SNF1LK) (Salt-inducible protein kinase) (Protein kinase KID2) Length = 776 Score = 175 bits (443), Expect = 9e-44 Identities = 82/166 (49%), Positives = 119/166 (71%) Frame = +3 Query: 63 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 242 Y + +TLG G+F VK+A H T +VAIKI+++ ++ + ++E K+ RE+++++L HP+ Sbjct: 27 YDVERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTRLDSSNLE-KIYREVQLMKLLNHPN 85 Query: 243 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 422 II+LY+V+E +Y+V E+ K+GE+FDY+ G L E EAR+ F QI+S V+YCH + + Sbjct: 86 IIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQILSAVEYCHNHHI 145 Query: 423 VHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 VHRDLK ENLLLD N D+K+ADFG N + G L T CGSP YAA Sbjct: 146 VHRDLKTENLLLDGNMDIKLADFGFGNFYKPGEPLSTWCGSPPYAA 191
>MARK3_HUMAN (P27448) MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1)| (Cdc25C-associated protein kinase 1) (cTAK1) (C-TAK1) (Serine/threonine protein kinase p78) (Ser/Thr protein kinase PAR-1) (Protein kinase STK10) Length = 776 Score = 173 bits (439), Expect = 3e-43 Identities = 88/190 (46%), Positives = 125/190 (65%), Gaps = 23/190 (12%) Frame = +3 Query: 60 NYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHP 239 NYR+ KT+G G+F KVK+A HI TG +VAIKI+++ ++ ++ K+ RE++I+++ HP Sbjct: 55 NYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQ-KLFREVRIMKILNHP 113 Query: 240 HIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQ------------ 383 +I++L+EVIE +Y++MEY GE+FDY+V GR++E+EAR F+Q Sbjct: 114 NIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQGCQAGQTIKVQV 173 Query: 384 -----------IISGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLK 530 I+S VQYCH+ +VHRDLK ENLLLD + ++KIADFG SN G L Sbjct: 174 SFDLLSLMFTFIVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGGKLD 233 Query: 531 TSCGSPNYAA 560 T CGSP YAA Sbjct: 234 TFCGSPPYAA 243
>GIN4_YEAST (Q12263) Serine/threonine-protein kinase GIN4 (EC 2.7.11.1)| Length = 1142 Score = 173 bits (438), Expect = 3e-43 Identities = 84/185 (45%), Positives = 127/185 (68%), Gaps = 14/185 (7%) Frame = +3 Query: 48 NPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEK---------- 197 N + +++G+TLG+GS GKV++A + TG + A+K++++ ++ Sbjct: 14 NTIGPWKLGETLGLGSTGKVQLARNGSTGQEAAVKVISKAVFNTGNVSGTSIVGSTTPDA 73 Query: 198 ----VKREIKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEA 365 ++REI I++L HP+++RLY+V E D+Y+V+EY + GELF+ +VE+G L E EA Sbjct: 74 LPYGIEREIIIMKLLNHPNVLRLYDVWETNTDLYLVLEYAEKGELFNLLVERGPLPEHEA 133 Query: 366 RRFFQQIISGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGS 545 RFF+QII GV YCH +VHRDLKPENLLLD+ ++KIADFG++ + +G L+TSCGS Sbjct: 134 IRFFRQIIIGVSYCHALGIVHRDLKPENLLLDHKYNIKIADFGMAALETEGKLLETSCGS 193 Query: 546 PNYAA 560 P+YAA Sbjct: 194 PHYAA 198
>SN1L2_CHICK (Q9IA88) Serine/threonine-protein kinase SNF1-like kinase 2 (EC| 2.7.11.1) (Qin-induced kinase) Length = 798 Score = 173 bits (438), Expect = 3e-43 Identities = 83/166 (50%), Positives = 118/166 (71%) Frame = +3 Query: 63 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 242 Y I +TLG G+F VK+A H T +VAIKI+++ ++ ++E K+ RE++I++L HPH Sbjct: 26 YDIERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTRLDPSNLE-KIYREVQIMKLLNHPH 84 Query: 243 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 422 II+LY+V+E +Y+V E+ K+GE+FD++ G L E EAR+ F QI+S V+YCH + + Sbjct: 85 IIKLYQVMETKDMLYIVTEFAKNGEMFDHLTSNGHLSESEARKKFWQILSAVEYCHSHHI 144 Query: 423 VHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 VHRDLK ENLLLD N ++K+ADFG N + G L T CGSP YAA Sbjct: 145 VHRDLKTENLLLDANMNIKLADFGFGNFYKSGEPLSTWCGSPPYAA 190
>SN1L2_PONPY (Q5REX1) Serine/threonine-protein kinase SNF1-like kinase 2 (EC| 2.7.11.1) Length = 925 Score = 172 bits (437), Expect = 4e-43 Identities = 85/166 (51%), Positives = 116/166 (69%) Frame = +3 Query: 63 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 242 Y I TLG G+F VK+ H T +VAIKI+++ ++ +++E K+ RE++I+++ HPH Sbjct: 20 YDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKSQLDAVNLE-KIYREVQIMKMLDHPH 78 Query: 243 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 422 II+LY+V+E + +Y+V EY K+GE+FDY+ GRL E EARR F QI+S V YCH + Sbjct: 79 IIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGRKI 138 Query: 423 VHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 VHRDLK ENLLLDNN ++KIADF N + G L T GSP YAA Sbjct: 139 VHRDLKAENLLLDNNMNIKIADFSFGNFFKSGELLATWRGSPPYAA 184
>KCC4_YEAST (P25389) Probable serine/threonine-protein kinase KCC4 (EC| 2.7.11.1) Length = 1037 Score = 172 bits (436), Expect = 6e-43 Identities = 81/191 (42%), Positives = 129/191 (67%), Gaps = 8/191 (4%) Frame = +3 Query: 12 ARWKMEAGGKDGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMD-- 185 A + + K + + +++G+TLG GS GKV++A+H +TGH+ A+K++++ N Sbjct: 4 ANTETHSAAKPSSTIGPWKLGETLGFGSTGKVQLAQHERTGHRTAVKVISKSIFNNNGNH 63 Query: 186 ------MEEKVKREIKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGR 347 + ++REI I++L HP+++ LY+V E ++Y+++EY + GELF+ +V+ G Sbjct: 64 SNDDSVLPYNIEREIVIMKLLSHPNVLSLYDVWETNNNLYLILEYAEKGELFNLLVDHGP 123 Query: 348 LQEQEARRFFQQIISGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFL 527 L E+EA F+QII G+ YCH +VHRDLKPENLLLD+ ++KIADFG++ + D L Sbjct: 124 LPEREAINCFRQIIIGISYCHALGIVHRDLKPENLLLDSFYNIKIADFGMAALQTDADLL 183 Query: 528 KTSCGSPNYAA 560 +TSCGSP+YAA Sbjct: 184 ETSCGSPHYAA 194
>SN1L1_MOUSE (Q60670) Serine/threonine-protein kinase SNF1-like kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase SNF1LK) (HRT-20) (Myocardial SNF1-like kinase) Length = 779 Score = 172 bits (435), Expect = 8e-43 Identities = 81/166 (48%), Positives = 119/166 (71%) Frame = +3 Query: 63 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 242 Y + +TLG G+F VK+A H T +VAIKI+++ ++ + ++E K+ RE+++++L HP+ Sbjct: 27 YDVERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTRLDSSNLE-KIYREVQLMKLLNHPN 85 Query: 243 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 422 II+LY+V+E +Y+V E+ K+GE+FDY+ G L E EAR+ F QI+S V+YCH + + Sbjct: 86 IIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARQKFWQILSAVEYCHNHHI 145 Query: 423 VHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 VHRDLK ENLLLD+N D+K+ADFG N + G L T GSP YAA Sbjct: 146 VHRDLKTENLLLDSNMDIKLADFGFGNFYKPGEPLSTCVGSPPYAA 191
>CIPK1_ORYSA (Q6X4A2) CIPK-like protein 1 (EC 2.7.11.1) (OsCK1)| Length = 449 Score = 170 bits (430), Expect = 3e-42 Identities = 82/170 (48%), Positives = 123/170 (72%), Gaps = 4/170 (2%) Frame = +3 Query: 63 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 242 Y +G+T+G G+F KV+ A++ + VAIKIL++ K++ + E+++REI ++L HP+ Sbjct: 20 YELGRTIGEGTFAKVRFAKNTENDEPVAIKILDKEKVQKHRLVEQIRREICTMKLVKHPN 79 Query: 243 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 422 ++RL+EV+ + A I++V+EYV GELF+ I GRL+E+EAR++FQQ+I+ V YCH V Sbjct: 80 VVRLFEVMGSKARIFIVLEYVTGGELFEIIATNGRLKEEEARKYFQQLINAVDYCHSRGV 139 Query: 423 VHRDLKPENLLLDNNCDVKIADFGLS----NVMRDGHFLKTSCGSPNYAA 560 HRDLK ENLLLD + ++K++DFGLS V DG L T+CG+PNY A Sbjct: 140 YHRDLKLENLLLDASGNLKVSDFGLSALTEQVKADG-LLHTTCGTPNYVA 188
>CPK15_ARATH (P92937) CBL-interacting serine/threonine-protein kinase 15 (EC| 2.7.11.1) (Serine/threonine-protein kinase ATPK10) (SOS2-like protein kinase PKS3) (SOS-interacting protein 2) (SNF1-related kinase 3.1) Length = 421 Score = 168 bits (425), Expect = 1e-41 Identities = 84/169 (49%), Positives = 117/169 (69%), Gaps = 3/169 (1%) Frame = +3 Query: 63 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 242 Y +GK LG G+F KV A H+KTG VAIK++++ +I + M E++KREI +RL HP+ Sbjct: 12 YEVGKFLGQGTFAKVYHARHLKTGDSVAIKVIDKERILKVGMTEQIKREISAMRLLRHPN 71 Query: 243 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 422 I+ L+EV+ + IY VME+VK GELF+ V G+L+E AR++FQQ++ V +CH V Sbjct: 72 IVELHEVMATKSKIYFVMEHVKGGELFNK-VSTGKLREDVARKYFQQLVRAVDFCHSRGV 130 Query: 423 VHRDLKPENLLLDNNCDVKIADFG---LSNVMRDGHFLKTSCGSPNYAA 560 HRDLKPENLLLD + ++KI+DFG LS+ R L T+CG+P Y A Sbjct: 131 CHRDLKPENLLLDEHGNLKISDFGLSALSDSRRQDGLLHTTCGTPAYVA 179
>CPK11_ARATH (O22932) CBL-interacting serine/threonine-protein kinase 11 (EC| 2.7.11.1) (SOS2-like protein kinase PKS5) (SOS-interacting protein 4) (SNF1-related kinase 3.22) Length = 435 Score = 166 bits (421), Expect = 3e-41 Identities = 88/186 (47%), Positives = 121/186 (65%), Gaps = 6/186 (3%) Frame = +3 Query: 21 KMEAGGKDGNP--LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKI-KNMDME 191 ++ AG D N Y +GK LG G+F KV A +TG VA+KILN++K+ N + Sbjct: 5 EIAAGSGDNNDALFGKYELGKLLGCGAFAKVFHARDRRTGQSVAVKILNKKKLLTNPALA 64 Query: 192 EKVKREIKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARR 371 +KREI I+R HP+I++L+EV+ + I+ ME+VK GELF+ I + GRL E +RR Sbjct: 65 NNIKREISIMRRLSHPNIVKLHEVMATKSKIFFAMEFVKGGELFNKISKHGRLSEDLSRR 124 Query: 372 FFQQIISGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLS---NVMRDGHFLKTSCG 542 +FQQ+IS V YCH V HRDLKPENLL+D N ++K++DFGLS + +R L T CG Sbjct: 125 YFQQLISAVGYCHARGVYHRDLKPENLLIDENGNLKVSDFGLSALTDQIRPDGLLHTLCG 184 Query: 543 SPNYAA 560 +P Y A Sbjct: 185 TPAYVA 190
>KKK1_YEAST (P34244) Probable serine/threonine-protein kinase YKL101W (EC| 2.7.11.1) Length = 1518 Score = 154 bits (389), Expect = 2e-37 Identities = 82/202 (40%), Positives = 125/202 (61%), Gaps = 36/202 (17%) Frame = +3 Query: 63 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRK-----------------------I 173 +++GKTLG GS G+V++A++++TG AIKI+ ++K + Sbjct: 81 WKLGKTLGKGSSGRVRLAKNMETGQLAAIKIVPKKKAFVHCSNNGTVPNSYSSSMVTSNV 140 Query: 174 KNMDMEEK------------VKREIKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGE 317 + + + ++REI I++L H +++ L+EV E +++Y+V+EYV GE Sbjct: 141 SSPSIASREHSNHSQTNPYGIEREIVIMKLISHTNVMALFEVWENKSELYLVLEYVDGGE 200 Query: 318 LFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMVVHRDLKPENLLLD-NNCDVKIADFG 494 LFDY+V KG+L E+EA +F+QI+ GV YCH + HRDLKPENLLLD N +KIADFG Sbjct: 201 LFDYLVSKGKLPEREAIHYFKQIVEGVSYCHSFNICHRDLKPENLLLDKKNRRIKIADFG 260 Query: 495 LSNVMRDGHFLKTSCGSPNYAA 560 ++ + LKTSCGSP+YA+ Sbjct: 261 MAALELPNKLLKTSCGSPHYAS 282
>MELK_MOUSE (Q61846) Maternal embryonic leucine zipper kinase (EC 2.7.11.1)| (Protein kinase PK38) (mPK38) Length = 643 Score = 147 bits (371), Expect = 2e-35 Identities = 80/171 (46%), Positives = 108/171 (63%), Gaps = 2/171 (1%) Frame = +3 Query: 54 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 233 LK Y + +T+G G F KVK+A H+ TG VAIKI+++ + + D+ +VK EI L+ Sbjct: 8 LKYYELYETIGTGGFAKVKLACHVLTGEMVAIKIMDKNALGS-DLP-RVKTEIDALKSLR 65 Query: 234 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 413 H HI +LY V+E I++V+EY GELFDYI+ + RL E+E R F+QI+S V Y H Sbjct: 66 HQHICQLYHVLETKNKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQILSAVAYVHS 125 Query: 414 NMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDG--HFLKTSCGSPNYAA 560 HRDLKPENLL D N +K+ DFGL + + L+T CGS YAA Sbjct: 126 QGYAHRDLKPENLLFDENHKLKLIDFGLCAKPKGNKDYHLQTCCGSLAYAA 176
>SNRK_HUMAN (Q9NRH2) SNF-related serine/threonine-protein kinase (EC 2.7.11.1)| (SNF1-related kinase) Length = 765 Score = 146 bits (368), Expect = 4e-35 Identities = 76/178 (42%), Positives = 115/178 (64%), Gaps = 3/178 (1%) Frame = +3 Query: 36 GKDGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIK 215 G DG Y + KTLG G F VK+A H+ TG KVA+K++++ K+ + + +E++ Sbjct: 7 GYDGKIAGLYDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKLDTLATGH-LFQEVR 65 Query: 216 ILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIV--EKGRLQEQEARRFFQQII 389 ++L HP+I+RLYEVI+ +Y+++E G++FDYI+ E+G L E A+++F QI+ Sbjct: 66 CMKLVQHPNIVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEG-LNEDLAKKYFAQIV 124 Query: 390 SGVQYCHRNMVVHRDLKPENLL-LDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 + YCH+ VVHRDLKPEN++ + VK+ DFG SN + G L TSCGS Y+A Sbjct: 125 HAISYCHKLHVVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQPGKKLTTSCGSLAYSA 182
>SNRK_RAT (Q63553) SNF-related serine/threonine-protein kinase (EC 2.7.11.1)| (SNF1-related kinase) Length = 746 Score = 146 bits (368), Expect = 4e-35 Identities = 76/178 (42%), Positives = 115/178 (64%), Gaps = 3/178 (1%) Frame = +3 Query: 36 GKDGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIK 215 G DG Y + KTLG G F VK+A H+ TG KVA+K++++ K+ + + +E++ Sbjct: 7 GYDGKIAGLYDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKLDTLATGH-LFQEVR 65 Query: 216 ILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIV--EKGRLQEQEARRFFQQII 389 ++L HP+I+RLYEVI+ +Y+++E G++FDYI+ E+G L E A+++F QI+ Sbjct: 66 CMKLVQHPNIVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEG-LNEDLAKKYFAQIV 124 Query: 390 SGVQYCHRNMVVHRDLKPENLL-LDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 + YCH+ VVHRDLKPEN++ + VK+ DFG SN + G L TSCGS Y+A Sbjct: 125 HAISYCHKLHVVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQPGKKLTTSCGSLAYSA 182
>SNRK_MOUSE (Q8VDU5) SNF-related serine/threonine-protein kinase (EC 2.7.11.1)| (SNF1-related kinase) Length = 748 Score = 146 bits (368), Expect = 4e-35 Identities = 76/178 (42%), Positives = 115/178 (64%), Gaps = 3/178 (1%) Frame = +3 Query: 36 GKDGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIK 215 G DG Y + KTLG G F VK+A H+ TG KVA+K++++ K+ + + +E++ Sbjct: 7 GYDGKIAGLYDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKLDTLATGH-LFQEVR 65 Query: 216 ILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIV--EKGRLQEQEARRFFQQII 389 ++L HP+I+RLYEVI+ +Y+++E G++FDYI+ E+G L E A+++F QI+ Sbjct: 66 CMKLVQHPNIVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEG-LNEDLAKKYFAQIV 124 Query: 390 SGVQYCHRNMVVHRDLKPENLL-LDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 + YCH+ VVHRDLKPEN++ + VK+ DFG SN + G L TSCGS Y+A Sbjct: 125 HAISYCHKLHVVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQPGKKLTTSCGSLAYSA 182
>KIN1_SCHPO (P22987) Protein kinase kin1 (EC 2.7.11.1)| Length = 891 Score = 145 bits (366), Expect = 8e-35 Identities = 80/185 (43%), Positives = 109/185 (58%), Gaps = 18/185 (9%) Frame = +3 Query: 60 NYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNR-----RKIKNMDMEEKVK------- 203 NY +GKT+G GS GKVK+A H+KTG + AIKI+ R K K E K Sbjct: 124 NYVLGKTIGAGSMGKVKVAHHLKTGEQFAIKIVTRLHPDITKAKAAASAEATKAAQSEKN 183 Query: 204 ------REIKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEA 365 RE + L HP+I +V + Y+V E+V G++ DYI+ G+L+E++A Sbjct: 184 KEIRTVREAALSTLLRHPYICEARDVYITNSHYYMVFEFVDGGQMLDYIISHGKLKEKQA 243 Query: 366 RRFFQQIISGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGS 545 R+F +QI S + Y H+N VVHRDLK EN+L+ D+KI DFGLSN+ R L+T CGS Sbjct: 244 RKFVRQIGSALSYLHQNSVVHRDLKIENILISKTGDIKIIDFGLSNLYRRQSRLRTFCGS 303 Query: 546 PNYAA 560 +AA Sbjct: 304 LYFAA 308
>MELK_HUMAN (Q14680) Maternal embryonic leucine zipper kinase (EC 2.7.11.1)| (hMELK) (Protein kinase PK38) (hPK38) Length = 651 Score = 145 bits (366), Expect = 8e-35 Identities = 79/171 (46%), Positives = 108/171 (63%), Gaps = 2/171 (1%) Frame = +3 Query: 54 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 233 LK Y + +T+G G F KVK+A HI TG VAIKI+++ + + D+ ++K EI+ L+ Sbjct: 8 LKYYELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTLGS-DLP-RIKTEIEALKNLR 65 Query: 234 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 413 H HI +LY V+E I++V+EY GELFDYI+ + RL E+E R F+QI+S V Y H Sbjct: 66 HQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHS 125 Query: 414 NMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDG--HFLKTSCGSPNYAA 560 HRDLKPENLL D +K+ DFGL + + L+T CGS YAA Sbjct: 126 QGYAHRDLKPENLLFDEYHKLKLIDFGLCAKPKGNKDYHLQTCCGSLAYAA 176
>CDR2_SCHPO (P87050) Mitosis inducer protein kinase cdr2 (EC 2.7.11.1)| Length = 775 Score = 143 bits (361), Expect = 3e-34 Identities = 64/166 (38%), Positives = 108/166 (65%) Frame = +3 Query: 63 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 242 + +G +LG G ++A+H +TG +K + + +++ E+ +LRL HP+ Sbjct: 10 WELGLSLGSGGPNSSRLAKHRETGQLAVVKPIVGWSELTSSQQARIEGELVLLRLIEHPN 69 Query: 243 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 422 +++L +VI A ++VV+EY+ GELFD ++ KG EQ+ +F QI+ G++YCH+ + Sbjct: 70 VLQLIDVISAQEQLFVVVEYMPGGELFDCMLRKGSFTEQDTAKFLWQILCGLEYCHKLHI 129 Query: 423 VHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 HRDLKPENL LD + +KI +FG++++ + G L+TSCGSP+YA+ Sbjct: 130 CHRDLKPENLYLDAHGSIKIGEFGMASIQQPGKLLQTSCGSPHYAS 175
>HUNK_PANTR (Q68UT7) Hormonally up-regulated neu tumor-associated kinase (EC| 2.7.11.1) Length = 714 Score = 143 bits (360), Expect = 4e-34 Identities = 78/172 (45%), Positives = 113/172 (65%), Gaps = 5/172 (2%) Frame = +3 Query: 60 NYRIG-KTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIK-NMDMEEKVKREIKILRLFM 233 NY IG + LG GSF KV+ H+ TG KVAIK++++++ K + + + ++RE +I ++ Sbjct: 60 NYLIGSRKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIR 119 Query: 234 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 413 HP+I +L +++E Y+VME G L I EK RL+E EARR+ +Q+IS V++ HR Sbjct: 120 HPNITQLLDILETENSYYLVMELCPGGNLMHKIYEKKRLEESEARRYIRQLISAVEHLHR 179 Query: 414 NMVVHRDLKPENLLLDNNCDVKIADFGLSN---VMRDGHFLKTSCGSPNYAA 560 VVHRDLK ENLLLD + ++K+ DFGLSN ++ T CGSP YAA Sbjct: 180 AGVVHRDLKIENLLLDEDNNIKLIDFGLSNCAGILGYSDPFSTQCGSPAYAA 231
>HUNK_HUMAN (P57058) Hormonally up-regulated neu tumor-associated kinase (EC| 2.7.11.1) (Serine/threonine-protein kinase MAK-V) (B19) Length = 714 Score = 143 bits (360), Expect = 4e-34 Identities = 78/172 (45%), Positives = 113/172 (65%), Gaps = 5/172 (2%) Frame = +3 Query: 60 NYRIG-KTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIK-NMDMEEKVKREIKILRLFM 233 NY IG + LG GSF KV+ H+ TG KVAIK++++++ K + + + ++RE +I ++ Sbjct: 60 NYLIGSRKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIR 119 Query: 234 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 413 HP+I +L +++E Y+VME G L I EK RL+E EARR+ +Q+IS V++ HR Sbjct: 120 HPNITQLLDILETENSYYLVMELCPGGNLMHKIYEKKRLEESEARRYIRQLISAVEHLHR 179 Query: 414 NMVVHRDLKPENLLLDNNCDVKIADFGLSN---VMRDGHFLKTSCGSPNYAA 560 VVHRDLK ENLLLD + ++K+ DFGLSN ++ T CGSP YAA Sbjct: 180 AGVVHRDLKIENLLLDEDNNIKLIDFGLSNCAGILGYSDPFSTQCGSPAYAA 231
>MYLK_DICDI (P25323) Myosin light chain kinase (EC 2.7.11.18) (MLCK)| Length = 295 Score = 142 bits (358), Expect = 6e-34 Identities = 75/171 (43%), Positives = 110/171 (64%), Gaps = 3/171 (1%) Frame = +3 Query: 57 KNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMH 236 K Y + LG G+F V + E+ +T + AIK++N+ ++ D E+ +K E+ IL+ H Sbjct: 6 KIYEFKEELGRGAFSIVYLGENKQTKQRYAIKVINKSEL-GKDYEKNLKMEVDILKKVNH 64 Query: 237 PHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRN 416 P+II L E+ + P +Y+VME V GELFD IVEKG E +A ++I+S V Y H Sbjct: 65 PNIIALKELFDTPEKLYLVMELVTGGELFDKIVEKGSYSEADAANLVKKIVSAVGYLHGL 124 Query: 417 MVVHRDLKPENLLL---DNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 +VHRDLKPENLLL +N+ +V IADFGLS ++ ++T+CG+P+Y A Sbjct: 125 NIVHRDLKPENLLLKSKENHLEVAIADFGLSKIIGQTLVMQTACGTPSYVA 175
>HUNK_MOUSE (O88866) Hormonally up-regulated neu tumor-associated kinase (EC| 2.7.11.1) (Serine/threonine-protein kinase MAK-V) Length = 714 Score = 142 bits (357), Expect = 8e-34 Identities = 78/172 (45%), Positives = 112/172 (65%), Gaps = 5/172 (2%) Frame = +3 Query: 60 NYRIG-KTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIK-NMDMEEKVKREIKILRLFM 233 NY IG + LG GSF KV+ H+ TG KVAIK++++++ K + + + ++RE +I ++ Sbjct: 60 NYLIGSRKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIR 119 Query: 234 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 413 HP+I +L +++E Y+VME G L I EK RL E EARR+ +Q+IS V++ HR Sbjct: 120 HPNITQLLDILETENSYYLVMELCPGGNLMHKIYEKKRLDEAEARRYIRQLISAVEHLHR 179 Query: 414 NMVVHRDLKPENLLLDNNCDVKIADFGLSN---VMRDGHFLKTSCGSPNYAA 560 VVHRDLK ENLLLD + ++K+ DFGLSN ++ T CGSP YAA Sbjct: 180 AGVVHRDLKIENLLLDEDNNIKLIDFGLSNCAGILGYSDPFSTQCGSPAYAA 231
>CHK2_MOUSE (Q9Z265) Serine/threonine-protein kinase Chk2 (EC 2.7.11.1)| Length = 546 Score = 140 bits (354), Expect = 2e-33 Identities = 74/174 (42%), Positives = 112/174 (64%), Gaps = 8/174 (4%) Frame = +3 Query: 63 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKI-----KNMDMEEKVKREIKILRL 227 Y + KTLG G+ G+VK+A KT KVAIKI+++R+ + D V+ EI+IL+ Sbjct: 224 YIMSKTLGSGACGEVKMAFERKTCQKVAIKIISKRRFALGSSREADTAPSVETEIEILKK 283 Query: 228 FMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYC 407 HP II++ +V +A D Y+V+E ++ GELFD +V RL+E + +F Q++ VQY Sbjct: 284 LNHPCIIKIKDVFDAE-DYYIVLELMEGGELFDRVVGNKRLKEATCKLYFYQMLVAVQYL 342 Query: 408 HRNMVVHRDLKPENLLL---DNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 H N ++HRDLKPEN+LL + +C +KI DFG S ++ + ++T CG+P Y A Sbjct: 343 HENGIIHRDLKPENVLLSSQEEDCLIKITDFGQSKILGETSLMRTLCGTPTYLA 396
>KIN4_YEAST (Q01919) Serine/threonine-protein kinase KIN4 (EC 2.7.11.1)| Length = 800 Score = 140 bits (354), Expect = 2e-33 Identities = 83/173 (47%), Positives = 106/173 (61%), Gaps = 7/173 (4%) Frame = +3 Query: 63 YRIGKTLGIGSFGKVKI-----AEHIKTGHKVAIKILNRRKIK-NMDMEEKVKREIKILR 224 Y IG TLG G FGKVK+ + + +VAIK++ R IK + D E K+ REI L+ Sbjct: 46 YIIGSTLGEGEFGKVKLGWTKASSSNEVPKQVAIKLIRRDTIKKDADKEIKIYREINALK 105 Query: 225 LFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQY 404 HP+II L EV++ I +V+E+V GE + YI K RL+E A R F Q+ISGV Y Sbjct: 106 HLTHPNIIYLEEVLQNSKYIGIVLEFVSGGEFYKYIQRKRRLKESSACRLFAQLISGVNY 165 Query: 405 CHRNMVVHRDLKPENLLLDNNCDVKIADFGLSN-VMRDGHFLKTSCGSPNYAA 560 H +VHRDLK ENLLLD + ++ I DFG N D +KTSCGSP YAA Sbjct: 166 MHYKGLVHRDLKLENLLLDKHENLVITDFGFVNEFFEDNELMKTSCGSPCYAA 218
>CDS1_SCHPO (Q09170) Serine/threonine-protein kinase cds1 (EC 2.7.11.1)| (Checkpoint kinase cds1) Length = 460 Score = 139 bits (350), Expect = 5e-33 Identities = 67/172 (38%), Positives = 112/172 (65%), Gaps = 5/172 (2%) Frame = +3 Query: 60 NYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKV----KREIKILRL 227 +Y I +TLG G+F VK+A + +G AIKI+N+RKI E++ +REI IL+ Sbjct: 166 HYEIIRTLGSGTFAVVKLAVEVNSGKWYAIKIINKRKILLTSSEKRATEMFQREIDILKS 225 Query: 228 FMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYC 407 HP +++ +E+ E ++++VMEYV+ G+L D+++ G + EQ+ + +Q++ + + Sbjct: 226 LHHPGVVQCHEIFENDDELFIVMEYVEGGDLMDFLIANGSIDEQDCKPLLKQLLETLLHL 285 Query: 408 HRNMVVHRDLKPENLLLDNNCDVKIADFGLSNVMR-DGHFLKTSCGSPNYAA 560 H+ V HRD+KPEN+L+ N+ +KI+DFGL+ V+ G FL+T CG+ Y A Sbjct: 286 HKQGVTHRDIKPENILITNDFHLKISDFGLAKVIHGTGTFLETFCGTMGYLA 337
>CHK2_HUMAN (O96017) Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (Cds1)| Length = 543 Score = 137 bits (346), Expect = 2e-32 Identities = 74/174 (42%), Positives = 110/174 (63%), Gaps = 8/174 (4%) Frame = +3 Query: 63 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKI-----KNMDMEEKVKREIKILRL 227 Y + KTLG G+ G+VK+A KT KVAIKI+++RK + D V+ EI+IL+ Sbjct: 220 YIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPALNVETEIEILKK 279 Query: 228 FMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYC 407 HP II++ +A D Y+V+E ++ GELFD +V RL+E + +F Q++ VQY Sbjct: 280 LNHPCIIKIKNFFDAE-DYYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLLAVQYL 338 Query: 408 HRNMVVHRDLKPENLLL---DNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 H N ++HRDLKPEN+LL + +C +KI DFG S ++ + ++T CG+P Y A Sbjct: 339 HENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETSLMRTLCGTPTYLA 392
>KCC1D_MOUSE (Q8BW96) Calcium/calmodulin-dependent protein kinase type 1D (EC| 2.7.11.17) (CaM kinase ID) (CaM kinase I delta) (CaMKI-delta) (CaM-KI delta) (CaMKI delta) (Camk1D) (CamKI-like protein kinase) (CKLiK) (mCKLiK) Length = 385 Score = 136 bits (342), Expect = 5e-32 Identities = 70/171 (40%), Positives = 103/171 (60%), Gaps = 3/171 (1%) Frame = +3 Query: 57 KNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMH 236 K + +TLG G+F +V +AE TG A+K + ++ +K E ++ EI +LR H Sbjct: 21 KIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGK--ESSIENEIAVLRKIKH 78 Query: 237 PHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRN 416 +I+ L ++ E+P +Y+VM+ V GELFD IVEKG E++A +Q++ V Y HR Sbjct: 79 ENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRM 138 Query: 417 MVVHRDLKPENLLL---DNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 +VHRDLKPENLL D + I+DFGLS + G + T+CG+P Y A Sbjct: 139 GIVHRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVA 189
>KCC1D_HUMAN (Q8IU85) Calcium/calmodulin-dependent protein kinase type 1D (EC| 2.7.11.17) (CaM kinase ID) (CaM kinase I delta) (CaMKI-delta) (CaM-KI delta) (CaMKI delta) (Camk1D) (CamKI-like protein kinase) (CKLiK) Length = 385 Score = 136 bits (342), Expect = 5e-32 Identities = 70/171 (40%), Positives = 103/171 (60%), Gaps = 3/171 (1%) Frame = +3 Query: 57 KNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMH 236 K + +TLG G+F +V +AE TG A+K + ++ +K E ++ EI +LR H Sbjct: 21 KIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGK--ESSIENEIAVLRKIKH 78 Query: 237 PHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRN 416 +I+ L ++ E+P +Y+VM+ V GELFD IVEKG E++A +Q++ V Y HR Sbjct: 79 ENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRM 138 Query: 417 MVVHRDLKPENLLL---DNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 +VHRDLKPENLL D + I+DFGLS + G + T+CG+P Y A Sbjct: 139 GIVHRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVA 189
>YP141_YEAST (Q03002) Putative serine/threonine-protein kinase YPL141C (EC| 2.7.11.1) Length = 865 Score = 134 bits (336), Expect = 2e-31 Identities = 80/178 (44%), Positives = 103/178 (57%), Gaps = 12/178 (6%) Frame = +3 Query: 63 YRIGKTLGIGSFGKVKIA----------EHIKTGHKVAIKILNRRKIKNMDMEE-KVKRE 209 Y +G TLG G FGKVK+ +VAIK++ R I N +E K+ RE Sbjct: 41 YILGSTLGEGEFGKVKLGWPKNFSNSSNSTFDFPKQVAIKLIKRDSISNDYRKEVKIYRE 100 Query: 210 IKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQII 389 I L+ HP+I++L EV++ I +V+EY GE + YI +K RL+E A R F Q+I Sbjct: 101 INALKHLSHPNIVKLEEVLQNSRYIGIVLEYACGGEFYKYIQKKRRLKEMNACRLFSQLI 160 Query: 390 SGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLSN-VMRDGHFLKTSCGSPNYAA 560 SGV Y H +VHRDLK ENLLLD N ++ I DFG N +KTSCGSP YAA Sbjct: 161 SGVHYIHSKGLVHRDLKLENLLLDKNENLVITDFGFVNEFCSRNELMKTSCGSPCYAA 218
>SAPK1_ORYSA (Q75LR7) Serine/threonine-protein kinase SAPK1 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 1) Length = 342 Score = 133 bits (334), Expect = 4e-31 Identities = 73/171 (42%), Positives = 98/171 (57%), Gaps = 2/171 (1%) Frame = +3 Query: 54 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 233 ++ Y + + +G G+FG K+ + T H A+K + R + ++E V+REI R Sbjct: 1 MERYEVMRDIGSGNFGVAKLVRDVATNHLFAVKFIER----GLKIDEHVQREIMNHRSLK 56 Query: 234 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 413 HP+IIR EV+ P + +VMEY GELF+ I GR E EAR FFQQ+ISGV YCH Sbjct: 57 HPNIIRFKEVVLTPTHLAIVMEYAAGGELFERICNAGRFSEDEARFFFQQLISGVSYCHS 116 Query: 414 NMVVHRDLKPENLLLDNNCD--VKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 V HRDLK EN LLD + +KI DFG S K++ G+P Y A Sbjct: 117 MQVCHRDLKLENTLLDGSVTPRLKICDFGYSKSSVLHSQPKSTVGTPAYIA 167
>KCC1A_RAT (Q63450) Calcium/calmodulin-dependent protein kinase type 1 (EC| 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha) Length = 374 Score = 132 bits (332), Expect = 7e-31 Identities = 74/187 (39%), Positives = 108/187 (57%), Gaps = 3/187 (1%) Frame = +3 Query: 9 GARWKMEAGGKDGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDM 188 G RWK +D Y LG G+F +V +AE +T VAIK + ++ ++ Sbjct: 7 GPRWKQAEDIRD-----IYDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKKALEGK-- 59 Query: 189 EEKVKREIKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEAR 368 E ++ EI +L HP+I+ L ++ E+ +Y++M+ V GELFD IVEKG E++A Sbjct: 60 EGSMENEIAVLHKIKHPNIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDAS 119 Query: 369 RFFQQIISGVQYCHRNMVVHRDLKPENLL---LDNNCDVKIADFGLSNVMRDGHFLKTSC 539 R Q++ V+Y H +VHRDLKPENLL LD + + I+DFGLS + G L T+C Sbjct: 120 RLIFQVLDAVKYLHDLGIVHRDLKPENLLYYSLDEDSKIMISDFGLSKMEDPGSVLSTAC 179 Query: 540 GSPNYAA 560 G+P Y A Sbjct: 180 GTPGYVA 186
>KCC1A_MOUSE (Q91YS8) Calcium/calmodulin-dependent protein kinase type 1 (EC| 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha) Length = 374 Score = 132 bits (332), Expect = 7e-31 Identities = 74/187 (39%), Positives = 108/187 (57%), Gaps = 3/187 (1%) Frame = +3 Query: 9 GARWKMEAGGKDGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDM 188 G RWK +D Y LG G+F +V +AE +T VAIK + ++ ++ Sbjct: 7 GPRWKQAEDIRD-----IYDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKKALEGK-- 59 Query: 189 EEKVKREIKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEAR 368 E ++ EI +L HP+I+ L ++ E+ +Y++M+ V GELFD IVEKG E++A Sbjct: 60 EGSMENEIAVLHKIKHPNIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDAS 119 Query: 369 RFFQQIISGVQYCHRNMVVHRDLKPENLL---LDNNCDVKIADFGLSNVMRDGHFLKTSC 539 R Q++ V+Y H +VHRDLKPENLL LD + + I+DFGLS + G L T+C Sbjct: 120 RLIFQVLDAVKYLHDLGIVHRDLKPENLLYYSLDEDSKIMISDFGLSKMEDPGSVLSTAC 179 Query: 540 GSPNYAA 560 G+P Y A Sbjct: 180 GTPGYVA 186
>CDR1_SCHPO (P07334) Mitosis inducer protein kinase cdr1 (EC 2.7.11.1) (Protein| kinase nim1) Length = 593 Score = 132 bits (331), Expect = 9e-31 Identities = 74/172 (43%), Positives = 103/172 (59%), Gaps = 1/172 (0%) Frame = +3 Query: 48 NPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRL 227 N + +R+GKTLG GS V++A+H KTG AIKI+ R + EI ++RL Sbjct: 7 NTIGVWRLGKTLGTGSTSCVRLAKHAKTGDLAAIKIIPIRYAS-------IGMEILMMRL 59 Query: 228 FMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYC 407 HP+I+RLY+V +Y+ +EYV GELF YI + G L E+EA + QI+ V +C Sbjct: 60 LRHPNILRLYDVWTDHQHMYLALEYVPDGELFHYIRKHGPLSEREAAHYLSQILDAVAHC 119 Query: 408 HRNMVVHRDLKPENLLLD-NNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 HR HRDLK EN+L+ N +KIADFG++ V + L+ CGS +Y A Sbjct: 120 HRFRFRHRDLKLENILIKVNEQQIKIADFGMATVEPNDSCLENYCGSLHYLA 171
>TSSK1_MOUSE (Q61241) Testis-specific serine/threonine-protein kinase 1 (EC| 2.7.11.1) (TSSK-1) (Testis-specific kinase 1) (TSK-1) (Serine/threonine-protein kinase 22A) Length = 364 Score = 131 bits (330), Expect = 1e-30 Identities = 74/174 (42%), Positives = 110/174 (63%), Gaps = 6/174 (3%) Frame = +3 Query: 57 KNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMH 236 + Y +G LG GS+ KVK A + VA+KI++R+K + +E+ + REI+IL + H Sbjct: 10 RGYIMGINLGEGSYAKVKSAYSERLKFNVAVKIIDRKKAPSDFLEKFLPREIEILAMLNH 69 Query: 237 PHIIRLYEVIE-APADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 413 I++ YE+ + +Y+VME G+L ++I +G LQE +AR+ F Q+ S ++YCH Sbjct: 70 RSIVKTYEIFATSDGKVYIVMELGVQGDLLEFIKTRGALQEDDARKKFHQLSSAIKYCHD 129 Query: 414 NMVVHRDLKPENLLLDNNCDVKIADFGLS-NVMRD--GHFL--KTSCGSPNYAA 560 VVHRDLK ENLLLD + ++K++DFG S +RD G + KT CGS YAA Sbjct: 130 LDVVHRDLKSENLLLDKDFNIKLSDFGFSKRCLRDDSGRLILSKTFCGSAAYAA 183
>KCC1A_HUMAN (Q14012) Calcium/calmodulin-dependent protein kinase type 1 (EC| 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha) Length = 370 Score = 131 bits (330), Expect = 1e-30 Identities = 74/187 (39%), Positives = 107/187 (57%), Gaps = 3/187 (1%) Frame = +3 Query: 9 GARWKMEAGGKDGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDM 188 G RWK +D Y LG G+F +V +AE +T VAIK + + ++ Sbjct: 7 GPRWKQAEDIRD-----IYDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKEALEGK-- 59 Query: 189 EEKVKREIKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEAR 368 E ++ EI +L HP+I+ L ++ E+ +Y++M+ V GELFD IVEKG E++A Sbjct: 60 EGSMENEIAVLHKIKHPNIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDAS 119 Query: 369 RFFQQIISGVQYCHRNMVVHRDLKPENLL---LDNNCDVKIADFGLSNVMRDGHFLKTSC 539 R Q++ V+Y H +VHRDLKPENLL LD + + I+DFGLS + G L T+C Sbjct: 120 RLIFQVLDAVKYLHDLGIVHRDLKPENLLYYSLDEDSKIMISDFGLSKMEDPGSVLSTAC 179 Query: 540 GSPNYAA 560 G+P Y A Sbjct: 180 GTPGYVA 186
>KIN1_YEAST (P13185) Protein kinase KIN1 (EC 2.7.11.1)| Length = 1064 Score = 130 bits (327), Expect = 3e-30 Identities = 70/195 (35%), Positives = 110/195 (56%), Gaps = 26/195 (13%) Frame = +3 Query: 54 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNR----------------------- 164 L ++ +T+G GS GKVK+A+H T A+KI+NR Sbjct: 117 LGDWEFVETVGAGSMGKVKLAKHRYTNEVCAVKIVNRATKAFLHKEQMLPPPKNEQDVLE 176 Query: 165 --RKI-KNMDMEEKVKREIKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIV 335 +K+ K + +++ RE + ++ HPHI RL+E+ Y++ EYV G+L DYI+ Sbjct: 177 RQKKLEKEISRDKRTIREASLGQILYHPHICRLFEMCTLSNHFYMLFEYVSGGQLLDYII 236 Query: 336 EKGRLQEQEARRFFQQIISGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRD 515 + G ++E +AR+F + I S + Y H N +VHRDLK EN+++ ++ ++KI DFGLSN+ Sbjct: 237 QHGSIREHQARKFARGIASALIYLHANNIVHRDLKIENIMISDSSEIKIIDFGLSNIYDS 296 Query: 516 GHFLKTSCGSPNYAA 560 L T CGS +AA Sbjct: 297 RKQLHTFCGSLYFAA 311
>SAPK2_ORYSA (Q84TC6) Serine/threonine-protein kinase SAPK2 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 2) Length = 339 Score = 130 bits (326), Expect = 3e-30 Identities = 71/171 (41%), Positives = 97/171 (56%), Gaps = 2/171 (1%) Frame = +3 Query: 54 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 233 ++ Y + K +G G+FG K+ ++T A+K + R ++E V+REI R Sbjct: 1 MERYEVIKDIGSGNFGVAKLVRDVRTKELFAVKFIER----GQKIDENVQREIMNHRSLR 56 Query: 234 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 413 HP+I+R EV+ P + +VMEY GELF+ I GR E EAR FFQQ+ISGV YCH Sbjct: 57 HPNIVRFKEVVLTPTHLAIVMEYAAGGELFERICSAGRFSEDEARFFFQQLISGVSYCHS 116 Query: 414 NMVVHRDLKPENLLLDNNC--DVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 + HRDLK EN LLD + +KI DFG S K++ G+P Y A Sbjct: 117 MQICHRDLKLENTLLDGSIAPRLKICDFGYSKSSLLHSQPKSTVGTPAYIA 167
>KIN2_YEAST (P13186) Serine/threonine-protein kinase KIN2 (EC 2.7.11.1)| Length = 1147 Score = 129 bits (324), Expect = 6e-30 Identities = 71/195 (36%), Positives = 107/195 (54%), Gaps = 26/195 (13%) Frame = +3 Query: 54 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNR----------------------- 164 L ++ +T+G GS GKVK+ +H +T IKI+NR Sbjct: 96 LGDWEFLETVGAGSMGKVKLVKHRQTKEICVIKIVNRASKAYLHKQHSLPSPKNESEILE 155 Query: 165 ---RKIKNMDMEEKVKREIKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIV 335 R K + +++ RE + ++ HPHI RL+E+ Y++ EYV G+L DYI+ Sbjct: 156 RQKRLEKEIARDKRTVREASLGQILYHPHICRLFEMCTMSNHFYMLFEYVSGGQLLDYII 215 Query: 336 EKGRLQEQEARRFFQQIISGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRD 515 + G L+E AR+F + I S +QY H N +VHRDLK EN+++ ++ ++KI DFGLSN+ Sbjct: 216 QHGSLKEHHARKFARGIASALQYLHANNIVHRDLKIENIMISSSGEIKIIDFGLSNIFDY 275 Query: 516 GHFLKTSCGSPNYAA 560 L T CGS +AA Sbjct: 276 RKQLHTFCGSLYFAA 290
>CDPK4_PLAF7 (Q8IBS5) Calcium-dependent protein kinase 4 (EC 2.7.11.1)| Length = 527 Score = 129 bits (324), Expect = 6e-30 Identities = 68/172 (39%), Positives = 105/172 (61%), Gaps = 4/172 (2%) Frame = +3 Query: 57 KNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMH 236 + Y+ K LG GSFG+V ++ TGH+ AIK+++++ +K +E + RE+++L++ H Sbjct: 67 EQYKGIKILGKGSFGEVILSRDKHTGHEYAIKVISKKHVKRKTDKESLLREVELLKMLDH 126 Query: 237 PHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRN 416 +I++LYE E Y+V + GELFD I+ + R E +A R +QI+SG+ Y H+N Sbjct: 127 INIMKLYEFFEDNNYYYLVSDVYTGGELFDEIISRKRFYEIDAARIIKQILSGITYMHKN 186 Query: 417 MVVHRDLKPENLLLD----NNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 VVHRDLKPEN+LL+ + +KI DFGLS +K G+ Y A Sbjct: 187 NVVHRDLKPENILLETKNKEDMIIKIIDFGLSTHFEYSKKMKDKIGTAYYIA 238
>CDPK4_PLAYO (Q7RJG2) Calcium-dependent protein kinase 4 (EC 2.7.11.1)| Length = 527 Score = 129 bits (323), Expect = 7e-30 Identities = 66/172 (38%), Positives = 106/172 (61%), Gaps = 4/172 (2%) Frame = +3 Query: 57 KNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMH 236 + Y+ K LG GSFG+V +++ TGH+ AIK+++++ +K ++ + RE+++L++ H Sbjct: 67 EQYKGIKILGKGSFGEVILSKDKHTGHEYAIKVISKKHVKRKTDKQSLLREVELLKMLDH 126 Query: 237 PHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRN 416 +I++LYE E Y+V + GELFD I+ + R E +A R +Q++SG+ Y H+N Sbjct: 127 INIMKLYEFFEDNNYYYLVSDVYSGGELFDEIISRKRFYEVDAARIIKQVLSGITYMHKN 186 Query: 417 MVVHRDLKPENLLLD----NNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 VVHRDLKPEN+LL+ + +KI DFGLS +K G+ Y A Sbjct: 187 NVVHRDLKPENILLETKNKEDMIIKIIDFGLSTHFEYSKKMKDKIGTAYYIA 238
>CDPK4_PLABA (P62345) Calcium-dependent protein kinase 4 (EC 2.7.11.1) (PbCDPK4)| Length = 527 Score = 129 bits (323), Expect = 7e-30 Identities = 66/172 (38%), Positives = 106/172 (61%), Gaps = 4/172 (2%) Frame = +3 Query: 57 KNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMH 236 + Y+ K LG GSFG+V +++ TGH+ AIK+++++ +K ++ + RE+++L++ H Sbjct: 67 EQYKGIKILGKGSFGEVILSKDKHTGHEYAIKVISKKHVKRKTDKQSLLREVELLKMLDH 126 Query: 237 PHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRN 416 +I++LYE E Y+V + GELFD I+ + R E +A R +Q++SG+ Y H+N Sbjct: 127 INIMKLYEFFEDNNYYYLVSDVYSGGELFDEIISRKRFYEVDAARIIKQVLSGITYMHKN 186 Query: 417 MVVHRDLKPENLLLD----NNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 VVHRDLKPEN+LL+ + +KI DFGLS +K G+ Y A Sbjct: 187 NVVHRDLKPENILLETKNKEDMIIKIIDFGLSTHFEYSKKMKDKIGTAYYIA 238
>KCC1_SCHPO (Q9P7I2) Calcium/calmodulin-dependent protein kinase type I (EC| 2.7.11.17) (CaMK-I) Length = 335 Score = 129 bits (323), Expect = 7e-30 Identities = 72/173 (41%), Positives = 103/173 (59%), Gaps = 7/173 (4%) Frame = +3 Query: 63 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRL--FMH 236 YR+G+ LG G++ V+ A HI+T A KI+N++ ++ ++ VK EI IL+ + H Sbjct: 31 YRVGRVLGGGTYATVREAVHIETNKMYAAKIMNKKMMEKK--QDFVKNEIAILKRVSYEH 88 Query: 237 PHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRN 416 P+I+ L + E ++Y++ E GELFD I KG E +A + S V+Y H N Sbjct: 89 PNILHLVDFFETVNNLYLITELATGGELFDRICAKGSFYEADAAALMRTTTSAVKYLHDN 148 Query: 417 MVVHRDLKPENLLL---DNNCDVKIADFGLSNVMRDGHF--LKTSCGSPNYAA 560 +VHRDLKPENLL D N D+ IADFGLS+ D + L T+CG+P Y A Sbjct: 149 GIVHRDLKPENLLYRSKDPNSDLLIADFGLSHFYEDSQYYMLMTACGTPEYMA 201
>TSSK1_HUMAN (Q9BXA7) Testis-specific serine/threonine-protein kinase 1 (EC| 2.7.11.1) (TSSK-1) (Testis-specific kinase 1) (TSK-1) (Serine/threonine-protein kinase 22A) Length = 367 Score = 128 bits (322), Expect = 1e-29 Identities = 74/174 (42%), Positives = 104/174 (59%), Gaps = 6/174 (3%) Frame = +3 Query: 57 KNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMH 236 + Y +G LG GS+ KVK A + VAIKI++R+K +E+ + REI+IL + H Sbjct: 10 RGYLLGINLGEGSYAKVKSAYSERLKFNVAIKIIDRKKAPADFLEKFLPREIEILAMLNH 69 Query: 237 PHIIRLYEVIEAP-ADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 413 II+ YE+ E +Y+VME G+L + I +G L E EAR+ F Q+ ++YCH Sbjct: 70 CSIIKTYEIFETSHGKVYIVMELAVQGDLLELIKTRGALHEDEARKKFHQLSLAIKYCHD 129 Query: 414 NMVVHRDLKPENLLLDNNCDVKIADFGLS-NVMRDGH----FLKTSCGSPNYAA 560 VVHRDLK +NLLLD + ++K++DF S +RD KT CGSP YAA Sbjct: 130 LDVVHRDLKCDNLLLDKDFNIKLSDFSFSKRCLRDDSGRMALSKTFCGSPAYAA 183
>DAPK2_MOUSE (Q8VDF3) Death-associated protein kinase 2 (EC 2.7.11.1) (DAP| kinase 2) (DAP-kinase-related protein 1) (DRP-1) Length = 370 Score = 128 bits (322), Expect = 1e-29 Identities = 69/173 (39%), Positives = 102/173 (58%), Gaps = 7/173 (4%) Frame = +3 Query: 63 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDM---EEKVKREIKILRLFM 233 Y IG+ LG G F VK TG + A K + +R+ + E+++RE+ ILR + Sbjct: 23 YDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVCREEIEREVSILRQVL 82 Query: 234 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 413 HP+II L++V E D+ +++E V GELFD++ +K L E+EA F +QI+ GV Y H Sbjct: 83 HPNIITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEATSFIKQILDGVNYLHT 142 Query: 414 NMVVHRDLKPEN-LLLDNNC---DVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 + H DLKPEN +LLD N +K+ DFGL++ + DG K G+P + A Sbjct: 143 KKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIEDGVEFKNIFGTPEFVA 195
>PLK4_HUMAN (O00444) Serine/threonine-protein kinase PLK4 (EC 2.7.11.21)| (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase Sak) (Serine/threonine-protein kinase 18) Length = 970 Score = 127 bits (320), Expect = 2e-29 Identities = 68/172 (39%), Positives = 105/172 (61%), Gaps = 2/172 (1%) Frame = +3 Query: 45 GNPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILR 224 G ++++++G LG GSF V AE I TG +VAIK+++++ + M ++V+ E+KI Sbjct: 6 GEKIEDFKVGNLLGKGSFAGVYRAESIHTGLEVAIKMIDKKAMYKAGMVQRVQNEVKIHC 65 Query: 225 LFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGR-LQEQEARRFFQQIISGVQ 401 HP I+ LY E +Y+V+E +GE+ Y+ + + E EAR F QII+G+ Sbjct: 66 QLKHPSILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITGML 125 Query: 402 YCHRNMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLK-TSCGSPNY 554 Y H + ++HRDL NLLL N ++KIADFGL+ ++ H T CG+PNY Sbjct: 126 YLHSHGILHRDLTLSNLLLTRNMNIKIADFGLATQLKMPHEKHYTLCGTPNY 177
>SAPK9_ORYSA (Q75V57) Serine/threonine-protein kinase SAPK9 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 9) Length = 361 Score = 127 bits (320), Expect = 2e-29 Identities = 74/168 (44%), Positives = 98/168 (58%), Gaps = 2/168 (1%) Frame = +3 Query: 63 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 242 Y + K +G G+FG ++ + +G VA+K ++R + ++E V+REI R HP+ Sbjct: 22 YELVKEIGSGNFGVARLMRNRASGDLVAVKYIDRGE----KIDENVQREIINHRSLRHPN 77 Query: 243 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 422 IIR EVI P + +VMEY GELF+ I GR E EAR FFQQ+ISGV YCH V Sbjct: 78 IIRFKEVILTPTHLAIVMEYASGGELFERICSAGRFSEDEARFFFQQLISGVSYCHSMQV 137 Query: 423 VHRDLKPENLLLDNNC--DVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 HRDLK EN LLD + +KI DFG S K++ G+P Y A Sbjct: 138 CHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIA 185
>TSSK2_HUMAN (Q96PF2) Testis-specific serine/threonine-protein kinase 2 (EC| 2.7.11.1) (TSSK-2) (Testis-specific kinase 2) (TSK-2) (Serine/threonine-protein kinase 22B) (DiGeorge syndrome protein G) Length = 358 Score = 127 bits (320), Expect = 2e-29 Identities = 74/174 (42%), Positives = 105/174 (60%), Gaps = 6/174 (3%) Frame = +3 Query: 57 KNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMH 236 K Y +G LG GS+ KVK A + VA+KI++R+K +E + RE+ IL H Sbjct: 10 KGYIVGINLGKGSYAKVKSAYSERLKFNVAVKIIDRKKTPTDFVERFLPREMDILATVNH 69 Query: 237 PHIIRLYEVIE-APADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 413 II+ YE+ E + IY++ME G+L ++I +G L E AR+ F+Q+ S V+YCH Sbjct: 70 GSIIKTYEIFETSDGRIYIIMELGVQGDLLEFIKCQGALHEDVARKMFRQLSSAVKYCHD 129 Query: 414 NMVVHRDLKPENLLLDNNCDVKIADFGLS-NVMRDGH----FLKTSCGSPNYAA 560 +VHRDLK ENLLLD + ++K++DFG S +RD + KT CGS YAA Sbjct: 130 LDIVHRDLKCENLLLDKDFNIKLSDFGFSKRCLRDSNGRIILSKTFCGSAAYAA 183
>KCC1B_RAT (O70150) Calcium/calmodulin-dependent protein kinase type 1B (EC| 2.7.11.17) (CaM kinase IB) (CaM kinase I beta) (CaMKI-beta) (CaM-KI beta) (Pregnancy up-regulated non-ubiquitously expressed CaM kinase homolog) Length = 343 Score = 127 bits (320), Expect = 2e-29 Identities = 67/169 (39%), Positives = 104/169 (61%), Gaps = 3/169 (1%) Frame = +3 Query: 63 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 242 Y I + LG G+F +V +A+ + H VA+K + ++ ++ E V+ EI +LR HP+ Sbjct: 15 YEIREKLGSGAFSEVMLAQERGSAHLVALKCIPKKALRGK--EALVENEIAVLRRISHPN 72 Query: 243 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 422 I+ L +V E+P+ +Y+ ME V GELFD I+E+G E++A Q++ V Y H + Sbjct: 73 IVALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAVSYLHSLGI 132 Query: 423 VHRDLKPENLLLD---NNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 VHRDLKPENLL + + ++DFGLS + + G+ L T+CG+P Y A Sbjct: 133 VHRDLKPENLLYATPFEDSKIMVSDFGLSKI-QAGNMLGTACGTPGYVA 180
>KCC1B_MOUSE (Q9QYK9) Calcium/calmodulin-dependent protein kinase type 1B (EC| 2.7.11.17) (CaM kinase IB) (CaM kinase I beta) (CaMKI-beta) (CaM-KI beta) (Pregnancy up-regulated non-ubiquitously expressed CaM kinase homolog) Length = 343 Score = 127 bits (320), Expect = 2e-29 Identities = 67/169 (39%), Positives = 104/169 (61%), Gaps = 3/169 (1%) Frame = +3 Query: 63 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 242 Y I + LG G+F +V +A+ + H VA+K + ++ ++ E V+ EI +LR HP+ Sbjct: 15 YEIREKLGSGAFSEVMLAQERGSAHLVALKCIPKKALRGK--EALVENEIAVLRRISHPN 72 Query: 243 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 422 I+ L +V E+P+ +Y+ ME V GELFD I+E+G E++A Q++ V Y H + Sbjct: 73 IVALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAVSYLHSLGI 132 Query: 423 VHRDLKPENLLLD---NNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 VHRDLKPENLL + + ++DFGLS + + G+ L T+CG+P Y A Sbjct: 133 VHRDLKPENLLYATPFEDSKIMVSDFGLSKI-QAGNMLGTACGTPGYVA 180
>DAPK3_HUMAN (O43293) Death-associated protein kinase 3 (EC 2.7.11.1) (DAP| kinase 3) (DAP-like kinase) (Dlk) (ZIP-kinase) Length = 454 Score = 127 bits (319), Expect = 2e-29 Identities = 65/174 (37%), Positives = 103/174 (59%), Gaps = 7/174 (4%) Frame = +3 Query: 60 NYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDM---EEKVKREIKILRLF 230 +Y +G+ LG G F V+ TG + A K + +R++ + E+++RE+ ILR Sbjct: 12 HYEMGEELGSGQFAIVRKCRQKGTGKEYAAKFIKKRRLSSSRRGVSREEIEREVNILREI 71 Query: 231 MHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCH 410 HP+II L+++ E D+ +++E V GELFD++ EK L E EA +F +QI+ GV Y H Sbjct: 72 RHPNIITLHDIFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGVHYLH 131 Query: 411 RNMVVHRDLKPEN-LLLDNNCD---VKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 + H DLKPEN +LLD N +K+ DFG+++ + G+ K G+P + A Sbjct: 132 SKRIAHFDLKPENIMLLDKNVPNPRIKLIDFGIAHKIEAGNEFKNIFGTPEFVA 185
>DAPK1_MOUSE (Q80YE7) Death-associated protein kinase 1 (EC 2.7.11.1) (DAP| kinase 1) Length = 1442 Score = 127 bits (319), Expect = 2e-29 Identities = 70/173 (40%), Positives = 101/173 (58%), Gaps = 7/173 (4%) Frame = +3 Query: 63 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDM---EEKVKREIKILRLFM 233 Y G+ LG G F VK TG + A K + +R+ K+ E ++RE+ IL+ Sbjct: 13 YDTGEELGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRGVSREDIEREVSILKEIR 72 Query: 234 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 413 HP++I L+EV E D+ +++E V GELFD++ EK L E+EA F +QI+SGV Y H Sbjct: 73 HPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQILSGVYYLHS 132 Query: 414 NMVVHRDLKPEN-LLLDNNCD---VKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 + H DLKPEN +LLD N +KI DFGL++ + G+ K G+P + A Sbjct: 133 LQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHKIDFGNEFKNIFGTPEFVA 185
>KCC1B_HUMAN (Q6P2M8) Calcium/calmodulin-dependent protein kinase type 1B (EC| 2.7.11.17) (CaM kinase IB) (CaM kinase I beta) (CaMKI-beta) (CaM-KI beta) (Pregnancy up-regulated non-ubiquitously expressed CaM kinase) Length = 343 Score = 127 bits (319), Expect = 2e-29 Identities = 67/169 (39%), Positives = 104/169 (61%), Gaps = 3/169 (1%) Frame = +3 Query: 63 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 242 Y I + LG G+F +V +A+ + H VA+K + ++ ++ E V+ EI +LR HP+ Sbjct: 15 YEIRERLGSGAFSEVVLAQERGSAHLVALKCIPKKALRGK--EALVENEIAVLRRISHPN 72 Query: 243 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 422 I+ L +V E+P+ +Y+ ME V GELFD I+E+G E++A Q++ V Y H + Sbjct: 73 IVALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAVSYLHSLGI 132 Query: 423 VHRDLKPENLLLD---NNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 VHRDLKPENLL + + ++DFGLS + + G+ L T+CG+P Y A Sbjct: 133 VHRDLKPENLLYATPFEDSKIMVSDFGLSKI-QAGNMLGTACGTPGYVA 180
>ASK2_ARATH (P43292) Serine/threonine-protein kinase ASK2 (EC 2.7.11.1)| Length = 353 Score = 127 bits (318), Expect = 3e-29 Identities = 78/172 (45%), Positives = 96/172 (55%), Gaps = 3/172 (1%) Frame = +3 Query: 54 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNR-RKIKNMDMEEKVKREIKILRLF 230 + Y + K LG G+FG ++ H T VA+K + R RKI +E V REI R Sbjct: 1 MDKYDVVKDLGAGNFGVARLLRHKDTKELVAMKYIERGRKI-----DENVAREIINHRSL 55 Query: 231 MHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCH 410 HP+IIR EVI P + +VMEY GELFD I GR E EAR FFQQ+I GV YCH Sbjct: 56 KHPNIIRFKEVILTPTHLAIVMEYASGGELFDRICTAGRFSEAEARYFFQQLICGVDYCH 115 Query: 411 RNMVVHRDLKPENLLLDNNCD--VKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 + HRDLK EN LLD + +KI DFG S K++ G+P Y A Sbjct: 116 SLQICHRDLKLENTLLDGSPAPLLKICDFGYSKSSILHSRPKSTVGTPAYIA 167
>PLK4_MOUSE (Q64702) Serine/threonine-protein kinase PLK4 (EC 2.7.11.21)| (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase Sak) (Serine/threonine-protein kinase 18) Length = 925 Score = 127 bits (318), Expect = 3e-29 Identities = 67/174 (38%), Positives = 108/174 (62%), Gaps = 4/174 (2%) Frame = +3 Query: 45 GNPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILR 224 G ++++++G LG GSF V AE I TG +VAIK+++++ + M ++V+ E+KI Sbjct: 6 GERIEDFKVGNLLGKGSFAGVYRAESIHTGLEVAIKMIDKKAMYKAGMVQRVQNEVKIHC 65 Query: 225 LFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGR-LQEQEARRFFQQIISGVQ 401 HP ++ LY E +Y+V+E +GE+ Y+ + + E+EAR F QII+G+ Sbjct: 66 QLKHPSVLELYNYFEDNNYVYLVLEMCHNGEMNRYLKNRMKPFSEREARHFMHQIITGML 125 Query: 402 YCHRNMVVHRDLKPENLLLDNNCDVKIADFGLS---NVMRDGHFLKTSCGSPNY 554 Y H + ++HRDL N+LL N ++KIADFGL+ N+ + H+ T CG+PNY Sbjct: 126 YLHSHGILHRDLTLSNILLTRNMNIKIADFGLATQLNMPHEKHY--TLCGTPNY 177
>DAPK1_HUMAN (P53355) Death-associated protein kinase 1 (EC 2.7.11.1) (DAP| kinase 1) Length = 1432 Score = 126 bits (317), Expect = 4e-29 Identities = 69/173 (39%), Positives = 101/173 (58%), Gaps = 7/173 (4%) Frame = +3 Query: 63 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDM---EEKVKREIKILRLFM 233 Y G+ LG G F VK TG + A K + +R+ K+ E ++RE+ IL+ Sbjct: 13 YDTGEELGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRGVSREDIEREVSILKEIQ 72 Query: 234 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 413 HP++I L+EV E D+ +++E V GELFD++ EK L E+EA F +QI++GV Y H Sbjct: 73 HPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQILNGVYYLHS 132 Query: 414 NMVVHRDLKPEN-LLLDNNCD---VKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 + H DLKPEN +LLD N +KI DFGL++ + G+ K G+P + A Sbjct: 133 LQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHKIDFGNEFKNIFGTPEFVA 185
>CHK1_XENLA (Q6DE87) Serine/threonine-protein kinase Chk1 (EC 2.7.11.1) (xChk1| protein) Length = 474 Score = 126 bits (317), Expect = 4e-29 Identities = 69/172 (40%), Positives = 106/172 (61%), Gaps = 3/172 (1%) Frame = +3 Query: 54 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 233 ++++ + +TLG G++G+V++A + KT VA+KI++ + D E +K+EI I R+ Sbjct: 6 VEDWDLVQTLGEGAYGEVQLAVNRKTEEAVAVKIVDMTRAA--DCPENIKKEICINRMLS 63 Query: 234 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 413 H +I+R Y Y+ +EY + GELFD I + EQ+A++FFQQ+I+GV+Y H Sbjct: 64 HTNIVRFYGHRREGNIQYLFLEYCRGGELFDRIEPDVGMPEQDAQKFFQQLIAGVEYLHS 123 Query: 414 NMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDG---HFLKTSCGSPNYAA 560 + HRD+KPENLLLD +KI+DFGL+ V R L CG+ Y A Sbjct: 124 IGITHRDIKPENLLLDERDQLKISDFGLATVFRHNGKERLLNKMCGTLPYVA 175
>TSSK2_MOUSE (O54863) Testis-specific serine/threonine-protein kinase 2 (EC| 2.7.11.1) (TSSK-2) (Testis-specific kinase 2) (TSK-2) (Serine/threonine-protein kinase 22B) Length = 357 Score = 125 bits (314), Expect = 8e-29 Identities = 75/174 (43%), Positives = 102/174 (58%), Gaps = 6/174 (3%) Frame = +3 Query: 57 KNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMH 236 K Y +G LG GS+ KVK A + VA+KI++R+K +E + RE+ IL H Sbjct: 10 KGYIVGINLGKGSYAKVKSAYSERLKFNVAVKIIDRKKTPTDFVERFLPREMDILATVNH 69 Query: 237 PHIIRLYEVIE-APADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 413 II+ YE+ E + IY+VME G+L +I +G L E + F+Q+ S V+YCH Sbjct: 70 RSIIKTYEIFETSDGRIYIVMELGVQGDLLTFIKCRGALHEDVGGKMFRQVSSAVKYCHD 129 Query: 414 NMVVHRDLKPENLLLDNNCDVKIADFGLS-NVMRDGH----FLKTSCGSPNYAA 560 VVHRDLK ENLLLD + ++K++DFG S +RDG KT CGS YAA Sbjct: 130 LDVVHRDLKCENLLLDKDFNIKLSDFGFSKGCLRDGSGRIVLSKTFCGSAAYAA 183
>SAPK7_ORYSA (Q7XQP4) Serine/threonine-protein kinase SAPK7 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 7) Length = 359 Score = 125 bits (313), Expect = 1e-28 Identities = 72/171 (42%), Positives = 97/171 (56%), Gaps = 2/171 (1%) Frame = +3 Query: 54 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 233 ++ Y + K +G G+FG ++ + +T VA+K + R + ++E V REI R Sbjct: 1 MERYELLKDIGAGNFGVARLMRNKETKELVAMKYIPR----GLKIDENVAREIINHRSLR 56 Query: 234 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 413 HP+IIR EV+ P + +VMEY GELFD I GR E EAR FFQQ+I GV YCH Sbjct: 57 HPNIIRFKEVVVTPTHLAIVMEYAAGGELFDRICNAGRFSEDEARYFFQQLICGVSYCHF 116 Query: 414 NMVVHRDLKPENLLLDNN--CDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 + HRDLK EN LLD + +KI DFG S K++ G+P Y A Sbjct: 117 MQICHRDLKLENTLLDGSPAPRLKICDFGYSKSSLLHSKPKSTVGTPAYIA 167
>KAPB_YEAST (P06245) cAMP-dependent protein kinase type 2 (EC 2.7.11.11) (PKA| 2) Length = 380 Score = 125 bits (313), Expect = 1e-28 Identities = 59/169 (34%), Positives = 104/169 (61%) Frame = +3 Query: 54 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 233 L +++I +TLG GSFG+V + + G AIK+L ++++ M E E ++L+L Sbjct: 67 LHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKQQVVKMKQVEHTNDERRMLKLVE 126 Query: 234 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 413 HP +IR++ + +I++VM+Y++ GELF + + R A+ + ++I ++Y H Sbjct: 127 HPFLIRMWGTFQDARNIFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVILALEYLHA 186 Query: 414 NMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 + +++RDLKPEN+LLD N +KI DFG + ++ + T CG+P+Y A Sbjct: 187 HNIIYRDLKPENILLDRNGHIKITDFGFAKEVQTVTW--TLCGTPDYIA 233
>DCAK1_HUMAN (O15075) Serine/threonine-protein kinase DCAMKL1 (EC 2.7.11.1)| (Doublecortin-like and CAM kinase-like 1) Length = 740 Score = 125 bits (313), Expect = 1e-28 Identities = 65/172 (37%), Positives = 103/172 (59%), Gaps = 4/172 (2%) Frame = +3 Query: 57 KNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMH 236 + Y++G+T+G G+F VK T + A+KI+ + K + E ++ E+ ILR H Sbjct: 388 ERYKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCRGK--EHMIQNEVSILRRVKH 445 Query: 237 PHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRN 416 P+I+ L E ++ P ++Y+VME VK G+LFD I + E++A + S ++Y H Sbjct: 446 PNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSL 505 Query: 417 MVVHRDLKPENLLL----DNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 +VHRD+KPENLL+ D + +K+ DFGL+ ++ DG L T CG+P Y A Sbjct: 506 NIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIV-DGP-LYTVCGTPTYVA 555
>DCAK1_MOUSE (Q9JLM8) Serine/threonine-protein kinase DCAMKL1 (EC 2.7.11.1)| (Doublecortin-like and CAM kinase-like 1) Length = 756 Score = 124 bits (312), Expect = 1e-28 Identities = 65/172 (37%), Positives = 103/172 (59%), Gaps = 4/172 (2%) Frame = +3 Query: 57 KNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMH 236 + Y++G+T+G G+F VK T + A+KI+ + K + E ++ E+ ILR H Sbjct: 404 ERYKVGRTIGDGNFAVVKECIERSTAREYALKIIKKSKCRGK--EHMIQNEVSILRRVKH 461 Query: 237 PHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRN 416 P+I+ L E ++ P ++Y+VME VK G+LFD I + E++A + S ++Y H Sbjct: 462 PNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTSKYTERDASGMLYNLASAIKYLHSL 521 Query: 417 MVVHRDLKPENLLL----DNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 +VHRD+KPENLL+ D + +K+ DFGL+ ++ DG L T CG+P Y A Sbjct: 522 NIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIV-DGP-LYTVCGTPTYVA 571
>DAPK3_RAT (O88764) Death-associated protein kinase 3 (EC 2.7.11.1) (DAP| kinase 3) (DAP-like kinase) (Dlk) (ZIP-kinase) Length = 448 Score = 124 bits (312), Expect = 1e-28 Identities = 65/174 (37%), Positives = 103/174 (59%), Gaps = 7/174 (4%) Frame = +3 Query: 60 NYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDM---EEKVKREIKILRLF 230 +Y +G+ LG G F V+ + TG + A K + +R++ + E+++RE+ ILR Sbjct: 12 HYEMGEELGSGQFAIVRKCQQKGTGMEYAAKFIKKRRLPSSRRGVSREEIEREVSILREI 71 Query: 231 MHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCH 410 HP+II L++V E D+ +++E V GELFD++ EK L E EA +F +QI+ GV Y H Sbjct: 72 RHPNIITLHDVFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGVHYLH 131 Query: 411 RNMVVHRDLKPEN-LLLDNNC---DVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 + H DLKPEN +LLD + +K+ DFG+++ + G K G+P + A Sbjct: 132 SKRIAHFDLKPENIMLLDKHAASPRIKLIDFGIAHRIEAGSEFKNIFGTPEFVA 185
>DAPK3_MOUSE (O54784) Death-associated protein kinase 3 (EC 2.7.11.1) (DAP| kinase 3) (DAP-like kinase) (Dlk) (ZIP-kinase) Length = 448 Score = 124 bits (312), Expect = 1e-28 Identities = 65/174 (37%), Positives = 103/174 (59%), Gaps = 7/174 (4%) Frame = +3 Query: 60 NYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDM---EEKVKREIKILRLF 230 +Y +G+ LG G F V+ + TG + A K + +R++ + E+++RE+ ILR Sbjct: 12 HYEMGEELGSGQFAIVRKCQQKGTGMEYAAKFIKKRRLPSSRRGVSREEIEREVSILREI 71 Query: 231 MHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCH 410 HP+II L++V E D+ +++E V GELFD++ EK L E EA +F +QI+ GV Y H Sbjct: 72 RHPNIITLHDVFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGVHYLH 131 Query: 411 RNMVVHRDLKPEN-LLLDNNC---DVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 + H DLKPEN +LLD + +K+ DFG+++ + G K G+P + A Sbjct: 132 SKRIAHFDLKPENIMLLDKHAASPRIKLIDFGIAHRIEAGSEFKNIFGTPEFVA 185
>DCAK1_RAT (O08875) Serine/threonine-protein kinase DCAMKL1 (EC 2.7.11.1)| (Doublecortin-like and CAM kinase-like 1) (Calcium/calmodulin-dependent protein kinase type I-like CPG16) Length = 433 Score = 124 bits (312), Expect = 1e-28 Identities = 65/172 (37%), Positives = 103/172 (59%), Gaps = 4/172 (2%) Frame = +3 Query: 57 KNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMH 236 + Y++G+T+G G+F VK T + A+KI+ + K + E ++ E+ ILR H Sbjct: 81 ERYKVGRTIGDGNFAVVKECIERSTAREYALKIIKKSKCRGK--EHMIQNEVSILRRVKH 138 Query: 237 PHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRN 416 P+I+ L E ++ P ++Y+VME VK G+LFD I + E++A + S ++Y H Sbjct: 139 PNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTSKYTERDASGMLYNLASAIKYLHSL 198 Query: 417 MVVHRDLKPENLLL----DNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 +VHRD+KPENLL+ D + +K+ DFGL+ ++ DG L T CG+P Y A Sbjct: 199 NIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIV-DGP-LYTVCGTPTYVA 248
>SAPK3_ORYSA (Q75V63) Serine/threonine-protein kinase SAPK3 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 3) (Protein kinase REK) Length = 334 Score = 124 bits (312), Expect = 1e-28 Identities = 74/170 (43%), Positives = 95/170 (55%), Gaps = 2/170 (1%) Frame = +3 Query: 57 KNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMH 236 + Y K LG G+FG ++ ++ VA+K + R K ++E V+REI R H Sbjct: 3 ERYEALKELGAGNFGVARLVRDKRSKELVAVKYIERGK----KIDENVQREIINHRSLRH 58 Query: 237 PHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRN 416 P+IIR EV P + +VMEY GELF+ I GR E EAR FFQQ+ISGV YCH Sbjct: 59 PNIIRFKEVCLTPTHLAIVMEYAAGGELFEQICTAGRFSEDEARYFFQQLISGVSYCHSL 118 Query: 417 MVVHRDLKPENLLLDNNCD--VKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 + HRDLK EN LLD + VKI DFG S K++ G+P Y A Sbjct: 119 EICHRDLKLENTLLDGSPTPRVKICDFGYSKSALLHSKPKSTVGTPAYIA 168
>DAPK2_HUMAN (Q9UIK4) Death-associated protein kinase 2 (EC 2.7.11.1) (DAP| kinase 2) (DAP-kinase-related protein 1) (DRP-1) Length = 370 Score = 124 bits (312), Expect = 1e-28 Identities = 67/173 (38%), Positives = 101/173 (58%), Gaps = 7/173 (4%) Frame = +3 Query: 63 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDM---EEKVKREIKILRLFM 233 Y IG+ LG G F VK TG + A K + +R+ + E+++RE+ ILR + Sbjct: 23 YDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVSREEIEREVSILRQVL 82 Query: 234 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 413 H ++I L++V E D+ +++E V GELFD++ +K L E+EA F +QI+ GV Y H Sbjct: 83 HHNVITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEATSFIKQILDGVNYLHT 142 Query: 414 NMVVHRDLKPEN-LLLDNNC---DVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 + H DLKPEN +LLD N +K+ DFGL++ + DG K G+P + A Sbjct: 143 KKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIEDGVEFKNIFGTPEFVA 195
>SAPK4_ORYSA (Q5N942) Serine/threonine-protein kinase SAPK4 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 4) Length = 360 Score = 124 bits (311), Expect = 2e-28 Identities = 71/171 (41%), Positives = 98/171 (57%), Gaps = 2/171 (1%) Frame = +3 Query: 54 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 233 ++ Y + +G G+FG ++ + +T VA+K + R ++E V REI R Sbjct: 1 MEKYEAVRDIGSGNFGVARLMRNRETRELVAVKCIER----GHRIDENVYREIINHRSLR 56 Query: 234 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 413 HP+IIR EVI P + +VME+ GELFD I ++GR E EAR FFQQ+I GV YCH Sbjct: 57 HPNIIRFKEVILTPTHLMIVMEFAAGGELFDRICDRGRFSEDEARYFFQQLICGVSYCHH 116 Query: 414 NMVVHRDLKPENLLLDNN--CDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 + HRDLK EN+LLD + +KI DFG S K++ G+P Y A Sbjct: 117 MQICHRDLKLENVLLDGSPAPRLKICDFGYSKSSVLHSRPKSAVGTPAYIA 167
>KCC4_MOUSE (P08414) Calcium/calmodulin-dependent protein kinase type IV (EC| 2.7.11.17) (CAM kinase-GR) (CaMK IV) Length = 469 Score = 124 bits (311), Expect = 2e-28 Identities = 73/179 (40%), Positives = 103/179 (57%), Gaps = 4/179 (2%) Frame = +3 Query: 36 GKDGNPLKNY-RIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREI 212 G + +PL ++ + LG G+ V + T A+K+L + K + V+ EI Sbjct: 32 GSNRDPLGDFFEVESELGRGATSIVYRCKQKGTQKPYALKVLKKTVDKKI-----VRTEI 86 Query: 213 KILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIIS 392 +L HP+II+L E+ E P +I +V+E V GELFD IVEKG E++AR +QI+ Sbjct: 87 GVLLRLSHPNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDARDAVKQILE 146 Query: 393 GVQYCHRNMVVHRDLKPENLLLDN---NCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 V Y H N +VHRDLKPENLL + +KIADFGLS ++ +KT CG+P Y A Sbjct: 147 AVAYLHENGIVHRDLKPENLLYATPAPDAPLKIADFGLSKIVEHQVLMKTVCGTPGYCA 205
>CHK1_CHICK (Q8AYC9) Serine/threonine-protein kinase Chk1 (EC 2.7.11.1)| Length = 476 Score = 124 bits (311), Expect = 2e-28 Identities = 67/172 (38%), Positives = 106/172 (61%), Gaps = 3/172 (1%) Frame = +3 Query: 54 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 233 ++++ + +TLG G++G+V++A + +T VA+KI++ ++ D E +K+EI I ++ Sbjct: 6 VEDWDLVQTLGEGAYGEVQLAVNRRTEEAVAVKIVDMKRAA--DCPENIKKEICINKMLN 63 Query: 234 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 413 H ++++ Y A Y+ +EY GELFD I + E EA+RFFQQ+I+GV Y H Sbjct: 64 HENVVKFYGHRREGATQYLFLEYCSGGELFDRIEPDIGMPEPEAQRFFQQLIAGVVYLHS 123 Query: 414 NMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDG---HFLKTSCGSPNYAA 560 + HRDLKPENLLLD ++KI+DFGL+ V + L CG+ Y A Sbjct: 124 MGITHRDLKPENLLLDERDNLKISDFGLATVFKHNGRERLLNKMCGTLPYVA 175
>KCC1_YEAST (P27466) Calcium/calmodulin-dependent protein kinase I (EC| 2.7.11.17) Length = 446 Score = 124 bits (311), Expect = 2e-28 Identities = 68/173 (39%), Positives = 105/173 (60%), Gaps = 5/173 (2%) Frame = +3 Query: 57 KNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDME-EKVKREIKILRLFM 233 K Y GKTLG G+FG V+ A++ +TG VA+KIL ++ +K ++ E + E+ IL+ Sbjct: 35 KKYVFGKTLGAGTFGVVRQAKNTETGEDVAVKILIKKALKGNKVQLEALYDELDILQRLH 94 Query: 234 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 413 HP+I+ + E+ Y++ + K GELFD I++KG+ E++A R +I+S V+Y H Sbjct: 95 HPNIVAFKDWFESKDKFYIITQLAKGGELFDRILKKGKFTEEDAVRILVEILSAVKYMHS 154 Query: 414 NMVVHRDLKPENLLLDNNCD---VKIADFGLSNVMR-DGHFLKTSCGSPNYAA 560 +VHRDLKPENLL + D + +ADFG++ ++ D L GS Y A Sbjct: 155 QNIVHRDLKPENLLYIDKSDESPLVVADFGIAKRLKSDEELLYKPAGSLGYVA 207
>SAPKA_ORYSA (Q75H77) Serine/threonine-protein kinase SAPK10 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 10) Length = 362 Score = 124 bits (311), Expect = 2e-28 Identities = 73/168 (43%), Positives = 94/168 (55%), Gaps = 2/168 (1%) Frame = +3 Query: 63 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 242 Y + + +G G+FG ++ G VA+K + R ++E V+REI R HP+ Sbjct: 23 YELVRDIGSGNFGVARLMRSRADGQLVAVKYIERGD----KIDENVQREIINHRSLRHPN 78 Query: 243 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 422 IIR EVI P + +VMEY GELF+ I GR E EAR FFQQ+ISGV YCH V Sbjct: 79 IIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLISGVSYCHSMQV 138 Query: 423 VHRDLKPENLLLDNNC--DVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 HRDLK EN LLD + +KI DFG S K++ G+P Y A Sbjct: 139 CHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIA 186
>ICL1_KLULA (Q6CWQ4) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 361 Score = 124 bits (310), Expect = 2e-28 Identities = 61/167 (36%), Positives = 99/167 (59%) Frame = +3 Query: 54 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 233 L+++ IGK LG G FGKV +H +TG A+K + +++I ++++ +RE++I F Sbjct: 97 LQDFEIGKILGKGKFGKVYCVKHRETGLICALKAMEKKEIVQYTIQKQFRREVEIQGSFK 156 Query: 234 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 413 H ++ +LY +Y++MEYV GEL+ ++ G L E A F Q+ + + Y H Sbjct: 157 HKNLTQLYGFFYDEKRVYLLMEYVYYGELYKFLKNNGPLNETLASYFVYQMANALDYMHS 216 Query: 414 NMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNY 554 ++HRD+KPEN+L+ N +K+ DFG S DG KT CG+ +Y Sbjct: 217 KNILHRDIKPENILIGFNNTIKLTDFGWSVYNEDGQKRKTLCGTIDY 263
>AURKB_RAT (O55099) Serine/threonine-protein kinase 12 (EC 2.7.11.1) (Aurora-| and Ipl1-like midbody-associated protein 1) (AIM-1) (Aurora-B) Length = 343 Score = 124 bits (310), Expect = 2e-28 Identities = 64/167 (38%), Positives = 98/167 (58%) Frame = +3 Query: 54 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 233 + N+ IG+ LG G FG V +A K+ VA+KIL + +I+ +E +++REI+I Sbjct: 77 IDNFEIGRPLGKGKFGNVYLAREKKSRFIVALKILFKSQIEKEGVEHQLRREIEIQAHLK 136 Query: 234 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 413 HP+I++LY IY+++EY GEL+ + + G EQ +++ + YCH+ Sbjct: 137 HPNILQLYNYFYDQQRIYLILEYAPRGELYKELQKSGTFDEQRTATIMEELSDALMYCHK 196 Query: 414 NMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNY 554 V+HRD+KPENLLL ++KIADFG S V KT CG+ +Y Sbjct: 197 KKVIHRDIKPENLLLGLQGELKIADFGWS-VHAPSLRRKTMCGTLDY 242
>KK31_SCHPO (Q9HFF4) Probable serine/threonine-protein kinase C110.01 (EC| 2.7.11.1) Length = 1023 Score = 123 bits (309), Expect = 3e-28 Identities = 75/192 (39%), Positives = 105/192 (54%), Gaps = 25/192 (13%) Frame = +3 Query: 60 NYRIGKTLGIGSFGKVKIAEHIKTGH--------KVAIKILNRRKIKNMDMEEKVKREIK 215 +Y +G+T+G G FGKVK+ + + +V IKI+ K ++ RE+ Sbjct: 491 SYILGRTIGTGEFGKVKLGWPLPKANSTIHRSTPQVVIKIV--LSTKQNCQTSRLMREVA 548 Query: 216 ILRLF--MHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQII 389 IL+ HPHI++ + ++ +V++YV GELFDYI+ + RL++ A R F Q+I Sbjct: 549 ILKGLGNNHPHIVKYLDFVKTKHHFGIVLDYVNGGELFDYILARRRLEDSVACRLFAQLI 608 Query: 390 SGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHF--------------- 524 SGV Y H VVHRDLK EN+LLD N ++ IADFG + GHF Sbjct: 609 SGVAYLHSRGVVHRDLKLENILLDTNRNIVIADFGFATTF--GHFNTLSEHSLPTEKPDL 666 Query: 525 LKTSCGSPNYAA 560 TSCGSP YAA Sbjct: 667 FSTSCGSPCYAA 678
>KAPCG_HUMAN (P22612) cAMP-dependent protein kinase, gamma-catalytic subunit (EC| 2.7.11.11) (PKA C-gamma) Length = 350 Score = 123 bits (308), Expect = 4e-28 Identities = 66/178 (37%), Positives = 103/178 (57%), Gaps = 6/178 (3%) Frame = +3 Query: 45 GNPLKN------YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKR 206 GNP +N + +TLG+GSFG+V + H +TG A+KILN++K+ M E + Sbjct: 31 GNPAQNTASSDQFERLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQVEHILN 90 Query: 207 EIKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQI 386 E +IL+ P +++L + + +Y+VMEYV GE+F + GR E A + Q+ Sbjct: 91 EKRILQAIDFPFLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQRVGRFSEPHACFYAAQV 150 Query: 387 ISGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 + VQY H ++HRDLKPENLL+D +++ DFG + ++ + T CG+P Y A Sbjct: 151 VLAVQYLHSLDLIHRDLKPENLLIDQQGYLQVTDFGFAKRVKGRTW--TLCGTPEYLA 206
>SAPK6_ORYSA (Q6ZI44) Serine/threonine-protein kinase SAPK6 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 6) Length = 365 Score = 123 bits (308), Expect = 4e-28 Identities = 71/171 (41%), Positives = 97/171 (56%), Gaps = 2/171 (1%) Frame = +3 Query: 54 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 233 ++ Y + K +G G+FG ++ + +T VA+K + R + ++E V REI R Sbjct: 1 MEKYELLKDIGSGNFGVARLMRNRETKELVAMKYIPR----GLKIDENVAREIINHRSLR 56 Query: 234 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 413 HP+IIR EV+ P + +VMEY GELFD I GR E E+R FFQQ+I GV YCH Sbjct: 57 HPNIIRFKEVVLTPTHLAIVMEYAAGGELFDRICSAGRFSEDESRYFFQQLICGVSYCHF 116 Query: 414 NMVVHRDLKPENLLLDNN--CDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 + HRDLK EN LLD + +KI DFG S K++ G+P Y A Sbjct: 117 MQICHRDLKLENTLLDGSPAPRLKICDFGYSKSSLLHSKPKSTVGTPAYIA 167
>KPSH1_MOUSE (Q91YA2) Serine/threonine-protein kinase H1 (EC 2.7.11.1) (PSK-H1)| Length = 423 Score = 122 bits (307), Expect = 5e-28 Identities = 73/191 (38%), Positives = 102/191 (53%), Gaps = 5/191 (2%) Frame = +3 Query: 3 PRGARWKMEAGGKDGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNM 182 PR AR D Y I +G GSF +V EH T AIK++ + K Sbjct: 77 PRRARVAKYRAKFDPRVTAKYDIKALIGRGSFSRVVRVEHRATRQPYAIKMI---ETKYR 133 Query: 183 DMEEKVKREIKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQE 362 + E + E+++LR H +II+L EV E +Y+VME GELFD I+ KG E++ Sbjct: 134 EGREVCESELRVLRRVRHANIIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERD 193 Query: 363 ARRFFQQIISGVQYCHRNMVVHRDLKPENLLL---DNNCDVKIADFGLSNVMRDGH--FL 527 A R Q ++ GV+Y H + HRDLKPENLL + + I DFGL++ + G + Sbjct: 194 ATRVLQMVLDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASARKKGDDCLM 253 Query: 528 KTSCGSPNYAA 560 KT+CG+P Y A Sbjct: 254 KTTCGTPEYIA 264
>KPSH1_HUMAN (P11801) Serine/threonine-protein kinase H1 (EC 2.7.11.1) (PSK-H1)| Length = 423 Score = 122 bits (307), Expect = 5e-28 Identities = 73/191 (38%), Positives = 102/191 (53%), Gaps = 5/191 (2%) Frame = +3 Query: 3 PRGARWKMEAGGKDGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNM 182 PR AR D Y I +G GSF +V EH T AIK++ + K Sbjct: 77 PRRARVAKYRAKFDPRVTAKYDIKALIGRGSFSRVVRVEHRATRQPYAIKMI---ETKYR 133 Query: 183 DMEEKVKREIKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQE 362 + E + E+++LR H +II+L EV E +Y+VME GELFD I+ KG E++ Sbjct: 134 EGREVCESELRVLRRVRHANIIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERD 193 Query: 363 ARRFFQQIISGVQYCHRNMVVHRDLKPENLLL---DNNCDVKIADFGLSNVMRDGH--FL 527 A R Q ++ GV+Y H + HRDLKPENLL + + I DFGL++ + G + Sbjct: 194 ATRVLQMVLDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASARKKGDDCLM 253 Query: 528 KTSCGSPNYAA 560 KT+CG+P Y A Sbjct: 254 KTTCGTPEYIA 264
>PHKG2_HUMAN (P15735) Phosphorylase b kinase gamma catalytic chain, testis/liver| isoform (EC 2.7.11.19) (PHK-gamma-T) (Phosphorylase kinase gamma subunit 2) (PSK-C3) Length = 406 Score = 122 bits (307), Expect = 5e-28 Identities = 64/166 (38%), Positives = 99/166 (59%), Gaps = 6/166 (3%) Frame = +3 Query: 81 LGIGSFGKVKIAEHIKTGHKVAIKILN----RRKIKNMD-MEEKVKREIKILRLFM-HPH 242 +G G V+ H TGH+ A+KI+ R + ++ + E +RE ILR HPH Sbjct: 30 IGRGVSSVVRRCVHRATGHEFAVKIMEVTAERLSPEQLEEVREATRRETHILRQVAGHPH 89 Query: 243 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 422 II L + E+ + +++V + ++ GELFDY+ EK L E+E R + ++ V + H N + Sbjct: 90 IITLIDSYESSSFMFLVFDLMRKGELFDYLTEKVALSEKETRSIMRSLLEAVSFLHANNI 149 Query: 423 VHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 VHRDLKPEN+LLD+N ++++DFG S + G L+ CG+P Y A Sbjct: 150 VHRDLKPENILLDDNMQIRLSDFGFSCHLEPGEKLRELCGTPGYLA 195
>STK6_XENLA (Q91820) Serine/threonine-protein kinase Eg2 (EC 2.7.11.1) (pEg2)| (p46Eg265) Length = 407 Score = 122 bits (306), Expect = 7e-28 Identities = 62/176 (35%), Positives = 105/176 (59%) Frame = +3 Query: 27 EAGGKDGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKR 206 E G K L+++ IG+ LG G FG V +A ++ +A+K+L + +++ +E +++R Sbjct: 128 EEGKKKQWCLEDFEIGRPLGKGKFGNVYLARERESKFILALKVLFKSQLEKAGVEHQLRR 187 Query: 207 EIKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQI 386 E++I HP+I+RLY + +Y++++Y GELF + + R +Q + + +Q+ Sbjct: 188 EVEIQSHLRHPNILRLYGYFHDASRVYLILDYAPGGELFRELQKCTRFDDQRSAMYIKQL 247 Query: 387 ISGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNY 554 + YCH V+HRD+KPENLLL +N ++KIADFG S V T CG+ +Y Sbjct: 248 AEALLYCHSKKVIHRDIKPENLLLGSNGELKIADFGWS-VHAPSSRRTTLCGTLDY 302
>RAD53_YEAST (P22216) Serine/threonine-protein kinase RAD53 (EC 2.7.11.1)| (Serine-protein kinase 1) Length = 821 Score = 122 bits (306), Expect = 7e-28 Identities = 68/167 (40%), Positives = 100/167 (59%), Gaps = 3/167 (1%) Frame = +3 Query: 69 IGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRK-IKNMDMEEKVKREIKILRLFMHPHI 245 I + +G G+F VK A TG A+KI+++RK I NMD V RE+++L+ HP I Sbjct: 200 IDEVVGQGAFATVKKAIERTTGKTFAVKIISKRKVIGNMD---GVTRELEVLQKLNHPRI 256 Query: 246 IRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMVV 425 +RL E Y+VME+V G+L D++ G + E R +QI++ ++Y H + Sbjct: 257 VRLKGFYEDTESYYMVMEFVSGGDLMDFVAAHGAVGEDAGREISRQILTAIKYIHSMGIS 316 Query: 426 HRDLKPENLLL--DNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 HRDLKP+N+L+ D+ VKI DFGL+ V +G F+KT CG+ Y A Sbjct: 317 HRDLKPDNILIEQDDPVLVKITDFGLAKVQGNGSFMKTFCGTLAYVA 363
>AAIP_WHEAT (Q02066) Abscisic acid-inducible protein kinase (EC 2.7.11.1)| (Fragment) Length = 332 Score = 122 bits (305), Expect = 9e-28 Identities = 70/161 (43%), Positives = 89/161 (55%), Gaps = 2/161 (1%) Frame = +3 Query: 84 GIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPHIIRLYEV 263 G G+FG K+ ++T A+K + R ++E V+REI R HP+IIR EV Sbjct: 1 GSGNFGVAKLVRDVRTKEHFAVKFIER----GHKIDEHVQREIMNHRSLKHPNIIRFKEV 56 Query: 264 IEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMVVHRDLKP 443 + P + +VMEY GELF I GR E E R FFQQ+ISGV YCH V HRDLK Sbjct: 57 VLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFFQQLISGVSYCHSMQVCHRDLKL 116 Query: 444 ENLLLDNNC--DVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 EN LLD + +KI DFG S K++ G+P Y A Sbjct: 117 ENTLLDGSVAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIA 157
>STK6L_XENLA (Q91819) Serine/threonine-protein kinase Eg2-like (EC 2.7.11.1)| (p46XlEg22) Length = 408 Score = 122 bits (305), Expect = 9e-28 Identities = 62/176 (35%), Positives = 105/176 (59%) Frame = +3 Query: 27 EAGGKDGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKR 206 E G K L+++ IG+ LG G FG V +A ++ +A+K+L + +++ +E +++R Sbjct: 128 EEGKKKQWCLEDFEIGRPLGKGKFGNVYLARERESKFILALKVLFKSQLEKAGVEHQLRR 187 Query: 207 EIKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQI 386 E++I HP+I+RLY + +Y++++Y GELF + + R +Q + + +Q+ Sbjct: 188 EVEIQSHLRHPNILRLYGYFHDASRVYLILDYAPGGELFRELQKCTRFDDQRSALYIKQL 247 Query: 387 ISGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNY 554 + YCH V+HRD+KPENLLL +N ++KIADFG S V T CG+ +Y Sbjct: 248 AEALLYCHSKKVIHRDIKPENLLLGSNGELKIADFGWS-VHAPSSRRTTLCGTLDY 302
>KCC4_RAT (P13234) Calcium/calmodulin-dependent protein kinase type IV (EC| 2.7.11.17) (CAM kinase-GR) (CaMK IV) (Calspermin) Length = 474 Score = 122 bits (305), Expect = 9e-28 Identities = 72/179 (40%), Positives = 101/179 (56%), Gaps = 4/179 (2%) Frame = +3 Query: 36 GKDGNPLKNY-RIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREI 212 G +PL ++ + LG G+ V + T A+K+L + K + V+ EI Sbjct: 32 GSKRDPLSDFFEVESELGRGATSIVYRCKQKGTQKPYALKVLKKTVDKKI-----VRTEI 86 Query: 213 KILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIIS 392 +L HP+II+L E+ E P +I +V+E V GELFD IVEKG E++A +QI+ Sbjct: 87 GVLLRLSHPNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILE 146 Query: 393 GVQYCHRNMVVHRDLKPENLLLDN---NCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 V Y H N +VHRDLKPENLL + +KIADFGLS ++ +KT CG+P Y A Sbjct: 147 AVAYLHENGIVHRDLKPENLLYATPAPDAPLKIADFGLSKIVEHQVLMKTVCGTPGYCA 205
>DCAK2_MOUSE (Q6PGN3) Serine/threonine-protein kinase DCAMKL2 (EC 2.7.11.1)| (Doublecortin-like and CAM kinase-like 2) Length = 756 Score = 121 bits (304), Expect = 1e-27 Identities = 68/173 (39%), Positives = 99/173 (57%), Gaps = 4/173 (2%) Frame = +3 Query: 54 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 233 L+ YRIGK +G G+F VK TG + A+KI++ K K E ++ E+ ILR Sbjct: 390 LEKYRIGKVIGDGNFAVVKECVDRYTGKEFALKIID--KAKCCGKEHLIENEVSILRRVK 447 Query: 234 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 413 HP+II L E +E D+++VME VK G+LFD I + E++ + + ++Y H Sbjct: 448 HPNIIMLVEEMETATDLFLVMELVKGGDLFDAITSSTKYTERDGSAMVYNLANALRYLHS 507 Query: 414 NMVVHRDLKPENLLL----DNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 +VHRD+KPENLL+ D +K+ DFGL+ V+ L T CG+P Y A Sbjct: 508 LSIVHRDIKPENLLVCEYPDGTKSLKLGDFGLATVVEGP--LYTVCGTPTYVA 558
>KAPCG_MACMU (O62846) cAMP-dependent protein kinase, gamma-catalytic subunit (EC| 2.7.11.11) (PKA C-gamma) (Fragment) Length = 208 Score = 121 bits (303), Expect = 2e-27 Identities = 63/178 (35%), Positives = 104/178 (58%), Gaps = 6/178 (3%) Frame = +3 Query: 45 GNPLKN------YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKR 206 GNP +N + KTLG GS+G+V + H +TG+ A+KIL+++K+ + E Sbjct: 30 GNPAQNTASSDQFERLKTLGTGSYGRVMLVRHRETGNHYAMKILDKQKVVRLKQVEHTLN 89 Query: 207 EIKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQI 386 E +IL+ P +++L + +++Y+VMEYV GE+F ++ GR E +A + Q+ Sbjct: 90 EKRILQAINFPFLVKLQFSFKDNSNLYLVMEYVPGGEMFSHLRRVGRFSEPQACFYAAQV 149 Query: 387 ISGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 + QY H ++HRDLKPENLL+D +++ DFG + ++ + T CG+P Y A Sbjct: 150 VLAFQYLHSLDLIHRDLKPENLLIDQQGYLQVTDFGFAKRVKGRTW--TLCGTPEYLA 205
>KPK2_PLAFK (Q02595) Probable serine/threonine-protein kinase 2 (EC 2.7.11.1)| Length = 510 Score = 121 bits (303), Expect = 2e-27 Identities = 66/169 (39%), Positives = 102/169 (60%), Gaps = 3/169 (1%) Frame = +3 Query: 63 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 242 Y + K +G GSF I +I G++V +K +++ K+K E V EI++LR MH + Sbjct: 111 YVLNKKIGKGSFSTAYIGTNILYGNRVVVKEVDKSKVK----ESNVYTEIEVLRKVMHKY 166 Query: 243 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 422 II+L E +Y+V+EY+K GELF+Y+ G EQ A++ ++++ ++ H N V Sbjct: 167 IIKLISAYEQEGFVYLVLEYLKGGELFEYLNNNGPYTEQVAKKAMKRVLIALEALHSNGV 226 Query: 423 VHRDLKPENLLLDNNCD---VKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 VHRDLK ENL+L+N D +KI DFGL++ + + + CGSP Y A Sbjct: 227 VHRDLKMENLMLENPNDPSSLKIIDFGLASFL-NSPSMNMRCGSPGYVA 274
>DUN1_YEAST (P39009) DNA damage response protein kinase DUN1 (EC 2.7.11.1)| Length = 513 Score = 120 bits (302), Expect = 2e-27 Identities = 65/190 (34%), Positives = 105/190 (55%), Gaps = 24/190 (12%) Frame = +3 Query: 63 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 242 Y +GK LG G + VK A++ KTG +VA+KI + ++ + ++ + E IL HP+ Sbjct: 200 YLLGKELGAGHYALVKEAKNKKTGQQVAVKIFHAQQNDDQKKNKQFREETNILMRVQHPN 259 Query: 243 IIRLYEVIEAPADI-----YVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYC 407 I+ L + P Y+V+E + GELF+ IV K L++ E++ F+Q+++G++Y Sbjct: 260 IVNLLDSFVEPISKSQIQKYLVLEKIDDGELFERIVRKTCLRQDESKALFKQLLTGLKYL 319 Query: 408 HRNMVVHRDLKPENLLL-------------------DNNCDVKIADFGLSNVMRDGHFLK 530 H ++HRD+KPEN+LL + + VKIADFGL+ + F Sbjct: 320 HEQNIIHRDIKPENILLNITRRENPSQVQLGPWDEDEIDIQVKIADFGLAKFTGEMQFTN 379 Query: 531 TSCGSPNYAA 560 T CG+P+Y A Sbjct: 380 TLCGTPSYVA 389
>SAPK8_ORYSA (Q7Y0B9) Serine/threonine-protein kinase SAPK8 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 8) Length = 371 Score = 120 bits (302), Expect = 2e-27 Identities = 71/168 (42%), Positives = 96/168 (57%), Gaps = 2/168 (1%) Frame = +3 Query: 63 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 242 Y + + +G G+FG ++ +T VA+K + R + +++ V+REI R HP+ Sbjct: 33 YELVRDIGSGNFGVARLMRDRRTMELVAVKYIERGE----KIDDNVQREIINHRSLKHPN 88 Query: 243 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 422 IIR EVI P + +VMEY GELF+ I + R E EAR FFQQ+ISGV YCH V Sbjct: 89 IIRFKEVILTPTHLAIVMEYASGGELFERICKNVRFSEDEARYFFQQLISGVSYCHSMQV 148 Query: 423 VHRDLKPENLLLDNN--CDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 HRDLK EN LLD + +KI DFG S K++ G+P Y A Sbjct: 149 CHRDLKLENTLLDGSPAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIA 196
>AURKB_MOUSE (O70126) Serine/threonine-protein kinase 12 (EC 2.7.11.1)| (Aurora-related kinase 2) (Serine/threonine-protein kinase 5) (STK-1) (Aurora-B) Length = 345 Score = 120 bits (301), Expect = 3e-27 Identities = 63/167 (37%), Positives = 97/167 (58%) Frame = +3 Query: 54 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 233 + N+ IG+ LG G FG V +A K+ VA+KIL + +I+ +E +++REI+I Sbjct: 79 IDNFEIGRPLGKGKFGNVYLAREKKSRFIVALKILFKSQIEKEGVEHQLRREIEIQAHLK 138 Query: 234 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 413 HP+I++LY IY+++EY GEL+ + + EQ +++ + YCH+ Sbjct: 139 HPNILQLYNYFYDQQRIYLILEYAPRGELYKELQKSRTFDEQRTATIMEELSDALTYCHK 198 Query: 414 NMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNY 554 V+HRD+KPENLLL ++KIADFG S V KT CG+ +Y Sbjct: 199 KKVIHRDIKPENLLLGLQGELKIADFGWS-VHAPSLRRKTMCGTLDY 244
>LOK_DROME (O61267) Ovarian-specific serine/threonine-protein kinase Lok (EC| 2.7.11.1) (Protein loki) (dMNK) Length = 476 Score = 120 bits (301), Expect = 3e-27 Identities = 55/177 (31%), Positives = 106/177 (59%), Gaps = 9/177 (5%) Frame = +3 Query: 57 KNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIK------NMDMEEKVKREIKI 218 K Y + + LG G++G V++ +T + A+KI+ + + N ++V E KI Sbjct: 172 KTYYVNRKLGSGAYGLVRLVYDTRTCQQFAMKIVKKNMLSGARPSTNFSDPDRVLNEAKI 231 Query: 219 LRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGV 398 ++ HP ++R++++++ P +Y+V+E+++ G+L + I+ L E ++ +F Q+ V Sbjct: 232 MKNLSHPCVVRMHDIVDKPDSVYMVLEFMRGGDLLNRIISNKLLSEDISKLYFYQMCHAV 291 Query: 399 QYCHRNMVVHRDLKPENLLLDNNCD---VKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 +Y H + HRDLKP+N+LL+ N + +K++DFGLS ++ ++T CG+P Y A Sbjct: 292 KYLHDRGITHRDLKPDNVLLETNDEETLLKVSDFGLSKFVQKDSVMRTLCGTPLYVA 348
>KAPCA_BOVIN (P00517) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 120 bits (301), Expect = 3e-27 Identities = 60/162 (37%), Positives = 100/162 (61%) Frame = +3 Query: 75 KTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPHIIRL 254 KTLG GSFG+V + +H++TG+ A+KIL+++K+ + E E +IL+ P +++L Sbjct: 47 KTLGTGSFGRVMLVKHMETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKL 106 Query: 255 YEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMVVHRD 434 + +++Y+VMEYV GE+F ++ GR E AR + QI+ +Y H +++RD Sbjct: 107 EFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRD 166 Query: 435 LKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 LKPENLL+D +++ DFG + ++ + T CG+P Y A Sbjct: 167 LKPENLLIDQQGYIQVTDFGFAKRVKGRTW--TLCGTPEYLA 206
>PHKG2_MOUSE (Q9DB30) Phosphorylase b kinase gamma catalytic chain, testis/liver| isoform (EC 2.7.11.19) (PHK-gamma-T) (Phosphorylase kinase gamma subunit 2) Length = 406 Score = 120 bits (301), Expect = 3e-27 Identities = 62/166 (37%), Positives = 100/166 (60%), Gaps = 6/166 (3%) Frame = +3 Query: 81 LGIGSFGKVKIAEHIKTGHKVAIKILN----RRKIKNMD-MEEKVKREIKILRLFM-HPH 242 +G G V+ H TG + A+KI+ R ++ ++ + + +RE+ ILR HPH Sbjct: 30 IGRGVSSVVRRCVHRATGDEFAVKIMEVSAERLSLEQLEEVRDATRREMHILRQVAGHPH 89 Query: 243 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 422 II L + E+ + +++V + ++ GELFDY+ EK L E+E R + ++ V + H N + Sbjct: 90 IITLIDSYESSSFMFLVFDLMRKGELFDYLTEKVALSEKETRSIMRSLLEAVSFLHANNI 149 Query: 423 VHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 VHRDLKPEN+LLD+N ++++DFG S + G L+ CG+P Y A Sbjct: 150 VHRDLKPENILLDDNMQIRLSDFGFSCHLEAGEKLRELCGTPGYLA 195
>AURKC_HUMAN (Q9UQB9) Serine/threonine-protein kinase 13 (EC 2.7.11.1)| (Aurora/Ipl1/Eg2 protein 2) (Aurora/Ipl1-related kinase 3) (Aurora-C) Length = 309 Score = 120 bits (301), Expect = 3e-27 Identities = 62/165 (37%), Positives = 97/165 (58%) Frame = +3 Query: 60 NYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHP 239 ++ IG+ LG G FG V +A ++ VA+K+L + +I+ +E +++REI+I HP Sbjct: 42 DFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQHP 101 Query: 240 HIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNM 419 +I+RLY +Y+++EY GEL+ + + +L EQ +++ + YCH Sbjct: 102 NILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEELADALTYCHDKK 161 Query: 420 VVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNY 554 V+HRD+KPENLLL +VKIADFG S V KT CG+ +Y Sbjct: 162 VIHRDIKPENLLLGFRGEVKIADFGWS-VHTPSLRRKTMCGTLDY 205
>IPL1_ASHGO (Q755C4) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 367 Score = 120 bits (301), Expect = 3e-27 Identities = 59/183 (32%), Positives = 103/183 (56%), Gaps = 5/183 (2%) Frame = +3 Query: 21 KMEAGGKDGNPLKN-----YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMD 185 K AGG + L+N + IGK LG G FG+V HI++G A+K + ++ I + Sbjct: 90 KARAGGVPLSKLQNLKLADFEIGKVLGKGKFGRVYCVRHIESGFVCALKAMEKKDIIQYN 149 Query: 186 MEEKVKREIKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEA 365 +E++ +RE++I HP++ +LY +Y++MEY+ +GEL+ ++ + + A Sbjct: 150 IEKQFRREVEIQSSLRHPNLTQLYGYFHDEKRVYLLMEYLVNGELYKHLKGRSHFNDVVA 209 Query: 366 RRFFQQIISGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGS 545 + Q+ + Y H ++HRD+KPEN+++ N +K+ DFG S + G KT CG+ Sbjct: 210 SYYVYQMADALDYMHERNILHRDIKPENIIIGFNNTIKLTDFGWSVITPKGSKRKTLCGT 269 Query: 546 PNY 554 +Y Sbjct: 270 VDY 272
>KCC4_HUMAN (Q16566) Calcium/calmodulin-dependent protein kinase type IV (EC| 2.7.11.17) (CAM kinase-GR) (CaMK IV) Length = 473 Score = 120 bits (301), Expect = 3e-27 Identities = 69/169 (40%), Positives = 96/169 (56%), Gaps = 3/169 (1%) Frame = +3 Query: 63 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 242 + + LG G+ V + T A+K+L + K + V+ EI +L HP+ Sbjct: 46 FEVESELGRGATSIVYRCKQKGTQKPYALKVLKKTVDKKI-----VRTEIGVLLRLSHPN 100 Query: 243 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 422 II+L E+ E P +I +V+E V GELFD IVEKG E++A +QI+ V Y H N + Sbjct: 101 IIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAVAYLHENGI 160 Query: 423 VHRDLKPENLLLDN---NCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 VHRDLKPENLL + +KIADFGLS ++ +KT CG+P Y A Sbjct: 161 VHRDLKPENLLYATPAPDAPLKIADFGLSKIVEHQVLMKTVCGTPGYCA 209
>KAPB2_BOVIN (P24256) cAMP-dependent protein kinase, beta-2-catalytic subunit| (EC 2.7.11.11) (PKA C-beta-2) Length = 397 Score = 120 bits (300), Expect = 3e-27 Identities = 64/182 (35%), Positives = 106/182 (58%) Frame = +3 Query: 15 RWKMEAGGKDGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEE 194 +W+ A G L+++ KTLG GSFG+V + +H T A+KIL+++K+ + E Sbjct: 76 KWENPAPNNAG--LEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIE 133 Query: 195 KVKREIKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRF 374 E +IL+ P ++RL + +++Y+VMEYV GE+F ++ GR E AR + Sbjct: 134 HTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFY 193 Query: 375 FQQIISGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNY 554 QI+ +Y H +++RDLKPENLL+D+ +++ DFG + ++ + T CG+P Y Sbjct: 194 AAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTW--TLCGTPEY 251 Query: 555 AA 560 A Sbjct: 252 LA 253
>KAPCA_HUMAN (P17612) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 120 bits (300), Expect = 3e-27 Identities = 63/180 (35%), Positives = 106/180 (58%) Frame = +3 Query: 21 KMEAGGKDGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKV 200 K E+ ++ L + KTLG GSFG+V + +H +TG+ A+KIL+++K+ + E Sbjct: 29 KWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHT 88 Query: 201 KREIKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQ 380 E +IL+ P +++L + +++Y+VMEYV GE+F ++ GR E AR + Sbjct: 89 LNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAA 148 Query: 381 QIISGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 QI+ +Y H +++RDLKPENLL+D +++ DFG + ++ + T CG+P Y A Sbjct: 149 QIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTW--TLCGTPEYLA 206
>KAPCA_CRIGR (P25321) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 120 bits (300), Expect = 3e-27 Identities = 63/180 (35%), Positives = 107/180 (59%) Frame = +3 Query: 21 KMEAGGKDGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKV 200 K E+ ++ L ++ KTLG GSFG+V + +H +TG+ A+KIL+++K+ + E Sbjct: 29 KWESPSQNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHT 88 Query: 201 KREIKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQ 380 E +IL+ P +++L + +++Y+VMEYV GE+F ++ GR E AR + Sbjct: 89 LNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAA 148 Query: 381 QIISGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 QI+ +Y H +++RDLKPENLL+D +++ DFG + ++ + T CG+P Y A Sbjct: 149 QIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTW--TLCGTPEYLA 206
>KAPB1_BOVIN (P05131) cAMP-dependent protein kinase, beta-1-catalytic subunit| (EC 2.7.11.11) (PKA C-beta-1) Length = 350 Score = 120 bits (300), Expect = 3e-27 Identities = 64/182 (35%), Positives = 106/182 (58%) Frame = +3 Query: 15 RWKMEAGGKDGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEE 194 +W+ A G L+++ KTLG GSFG+V + +H T A+KIL+++K+ + E Sbjct: 29 KWENPAPNNAG--LEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIE 86 Query: 195 KVKREIKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRF 374 E +IL+ P ++RL + +++Y+VMEYV GE+F ++ GR E AR + Sbjct: 87 HTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFY 146 Query: 375 FQQIISGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNY 554 QI+ +Y H +++RDLKPENLL+D+ +++ DFG + ++ + T CG+P Y Sbjct: 147 AAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTW--TLCGTPEY 204 Query: 555 AA 560 A Sbjct: 205 LA 206
>PHKG2_RAT (P31325) Phosphorylase b kinase gamma catalytic chain, testis/liver| isoform (EC 2.7.11.19) (PHK-gamma-T) (Phosphorylase kinase gamma subunit 2) Length = 406 Score = 120 bits (300), Expect = 3e-27 Identities = 62/166 (37%), Positives = 100/166 (60%), Gaps = 6/166 (3%) Frame = +3 Query: 81 LGIGSFGKVKIAEHIKTGHKVAIKILN----RRKIKNMD-MEEKVKREIKILRLFM-HPH 242 +G G V+ H TG + A+KI+ R ++ ++ + + +RE+ ILR HPH Sbjct: 30 IGRGVSSVVRRCVHRATGDEFAVKIMEVSAERLSLEQLEEVRDATRREMHILRQVAGHPH 89 Query: 243 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 422 II L + E+ + +++V + ++ GELFDY+ EK L E+E R + ++ V + H N + Sbjct: 90 IITLIDSYESSSFMFLVFDLMRKGELFDYLTEKVALSEKETRSIMRSLLEAVNFLHVNNI 149 Query: 423 VHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 VHRDLKPEN+LLD+N ++++DFG S + G L+ CG+P Y A Sbjct: 150 VHRDLKPENILLDDNMQIRLSDFGFSCHLEPGEKLRELCGTPGYLA 195
>KAPC_DICDI (P34099) cAMP-dependent protein kinase catalytic subunit (EC| 2.7.11.11) Length = 648 Score = 120 bits (300), Expect = 3e-27 Identities = 59/169 (34%), Positives = 97/169 (57%) Frame = +3 Query: 54 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 233 LK ++ + LG G+FGKV + ++ K G A+K LN+ + + E + E IL Sbjct: 333 LKEFKQIRVLGTGTFGKVYLIQNTKDGCYYAMKCLNKAYVVQLKQVEHLNSEKSILSSIH 392 Query: 234 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 413 HP I+ LY+ + +Y++ EYV GE+F ++ + + A+ + +I+ +++ H+ Sbjct: 393 HPFIVNLYQAFQDEKKLYLLFEYVAGGEVFTHLRKSMKFSNSTAKFYAAEIVLALEFLHK 452 Query: 414 NMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 +V+RDLKPENLL+DN +KI DFG + + D F T CG+P Y A Sbjct: 453 QNIVYRDLKPENLLIDNQGHIKITDFGFAKRVEDRTF--TLCGTPEYLA 499
>CHK1_DROME (O61661) Serine/threonine-protein kinase grp (EC 2.7.11.1) (Protein| grapes) (Chk1 homolog) Length = 512 Score = 120 bits (300), Expect = 3e-27 Identities = 62/172 (36%), Positives = 105/172 (61%), Gaps = 3/172 (1%) Frame = +3 Query: 54 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 233 ++ + + +TLG G++G+VK+ + +TG VA+K+++ +K + D V++E+ I ++ Sbjct: 19 VEGWTLAQTLGEGAYGEVKLLINRQTGEAVAMKMVDLKK--HPDAANSVRKEVCIQKMLQ 76 Query: 234 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 413 HI+R + + Y+ +EY GELFD I + + EA+R+F Q++SG+ Y H+ Sbjct: 77 DKHILRFFGKRSQGSVEYIFLEYAAGGELFDRIEPDVGMPQHEAQRYFTQLLSGLNYLHQ 136 Query: 414 NMVVHRDLKPENLLLDNNCDVKIADFGLSNVMR---DGHFLKTSCGSPNYAA 560 + HRDLKPENLLLD + +VKI+DFG++ + R L CG+ Y A Sbjct: 137 RGIAHRDLKPENLLLDEHDNVKISDFGMATMFRCKGKERLLDKRCGTLPYVA 188
>ASK1_ARATH (P43291) Serine/threonine-protein kinase ASK1 (EC 2.7.11.1)| Length = 363 Score = 120 bits (300), Expect = 3e-27 Identities = 70/171 (40%), Positives = 94/171 (54%), Gaps = 2/171 (1%) Frame = +3 Query: 54 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 233 + Y + K +G G+FG ++ + + VA+K + R ++E V REI R Sbjct: 1 MDKYELVKDIGAGNFGVARLMKVKNSKELVAMKYIER----GPKIDENVAREIINHRSLR 56 Query: 234 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 413 HP+IIR EV+ P + + MEY GELF+ I GR E EAR FFQQ+ISGV YCH Sbjct: 57 HPNIIRFKEVVLTPTHLAIAMEYAAGGELFERICSAGRFSEDEARYFFQQLISGVSYCHA 116 Query: 414 NMVVHRDLKPENLLLDNN--CDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 + HRDLK EN LLD + +KI DFG S K++ G+P Y A Sbjct: 117 MQICHRDLKLENTLLDGSPAPRLKICDFGYSKSSLLHSRPKSTVGTPAYIA 167
>TSSK3_MOUSE (Q9D2E1) Testis-specific serine/threonine-protein kinase 3 (EC| 2.7.11.1) (TSSK-3) (Testis-specific kinase 3) (TSK-3) (Serine/threonine-protein kinase 22C) Length = 268 Score = 119 bits (299), Expect = 4e-27 Identities = 67/169 (39%), Positives = 104/169 (61%), Gaps = 3/169 (1%) Frame = +3 Query: 63 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 242 Y++GKT+G G++ KVK A K KVAIKI+++ ++ + RE++I+R H + Sbjct: 10 YQLGKTIGEGTYSKVKEAFSKKHQRKVAIKIIDKMGGPEEFIQRFLPRELQIVRTLDHKN 69 Query: 243 IIRLYEVIE-APADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNM 419 II++YE++E A IY+VME + G++FD ++ G L E A+ F+Q++ ++YCH Sbjct: 70 IIQVYEMLESADGKIYLVMELAEGGDVFDCVLNGGPLPESRAKALFRQMVEAIRYCHGCG 129 Query: 420 VVHRDLKPENLLLDNNCDVKIADFGLSNVMRDG--HFLKTSCGSPNYAA 560 V HRDLK EN LL ++K+ DFG + V+ +T CGS YAA Sbjct: 130 VAHRDLKCENALL-QGFNLKLTDFGFAKVLPKSRRELSQTFCGSTAYAA 177
>KAPCA_SHEEP (Q9MZD9) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 119 bits (299), Expect = 4e-27 Identities = 60/162 (37%), Positives = 99/162 (61%) Frame = +3 Query: 75 KTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPHIIRL 254 KTLG GSFG+V + +H +TG+ A+KIL+++K+ + E E +IL+ P +++L Sbjct: 47 KTLGTGSFGRVMLVKHTETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKL 106 Query: 255 YEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMVVHRD 434 + +++Y+VMEYV GE+F ++ GR E AR + QI+ +Y H +++RD Sbjct: 107 EFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRD 166 Query: 435 LKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 LKPENLL+D +++ DFG + ++ + T CG+P Y A Sbjct: 167 LKPENLLIDQQGYIQVTDFGFAKRVKGRTW--TLCGTPEYLA 206
>CDPK3_ORYSA (P53684) Calcium-dependent protein kinase, isoform 11 (EC 2.7.11.1)| (CDPK 11) Length = 542 Score = 119 bits (299), Expect = 4e-27 Identities = 70/180 (38%), Positives = 100/180 (55%), Gaps = 4/180 (2%) Frame = +3 Query: 33 GGKDGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREI 212 G K + ++Y IG+ LG G FG + I TG + A K + +RK+ + E V+REI Sbjct: 69 GRKTADLREHYIIGRKLGQGQFGTTYLCTEINTGCEYACKTIPKRKLITKEDVEDVRREI 128 Query: 213 KILR-LFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQII 389 +I+ L H +++ + +V E +++VME GELFD I EKG E++A + I+ Sbjct: 129 QIMHHLSGHKNVVAIKDVYEDGQAVHIVMELCAGGELFDRIQEKGHYSERKAAELIRIIV 188 Query: 390 SGVQYCHRNMVVHRDLKPENLLL---DNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 S V CH V+HRDLKPEN LL D++ +K DFGLS + G GSP Y A Sbjct: 189 SIVAMCHSLGVMHRDLKPENFLLLDKDDDLSIKAIDFGLSVFFKPGQVFTELVGSPYYVA 248
>KPSH1_PINFU (Q4KTY1) Serine/threonine-protein kinase H1 homolog (EC 2.7.11.1)| Length = 415 Score = 119 bits (299), Expect = 4e-27 Identities = 68/170 (40%), Positives = 98/170 (57%), Gaps = 4/170 (2%) Frame = +3 Query: 63 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 242 Y I +G G+F KV EH T AIK+++R + K E + E+ +LR H + Sbjct: 80 YDIKALIGRGNFSKVVRVEHRVTKQPYAIKMIDRVQGK-----EVFESEVAVLRRVKHSY 134 Query: 243 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 422 II+L EV E +Y+VME GELFD I+ KG E++A R ++ GV+Y H + Sbjct: 135 IIQLIEVFETKDKVYMVMELATGGELFDRIIAKGSFTERDATRVLNMVLDGVKYLHGLGI 194 Query: 423 VHRDLKPENLLL---DNNCDVKIADFGLSNVMR-DGHFLKTSCGSPNYAA 560 HRDLKPENLL ++ + I DFGLS+ + +F++T+CG+P Y A Sbjct: 195 THRDLKPENLLYYHPGHDSKIMITDFGLSSTRKGPENFMRTTCGTPEYIA 244
>KAPCA_PIG (P36887) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 119 bits (298), Expect = 6e-27 Identities = 60/162 (37%), Positives = 99/162 (61%) Frame = +3 Query: 75 KTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPHIIRL 254 KTLG GSFG+V + +H +TG+ A+KIL+++K+ + E E +IL+ P +++L Sbjct: 47 KTLGTGSFGRVMLVKHKETGNHFAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKL 106 Query: 255 YEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMVVHRD 434 + +++Y+VMEYV GE+F ++ GR E AR + QI+ +Y H +++RD Sbjct: 107 EYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRD 166 Query: 435 LKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 LKPENLL+D +++ DFG + ++ + T CG+P Y A Sbjct: 167 LKPENLLIDQQGYIQVTDFGFAKRVKGRTW--TLCGTPEYLA 206
>SAPK5_ORYSA (Q7XKA8) Serine/threonine-protein kinase SAPK5 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 5) Length = 370 Score = 119 bits (298), Expect = 6e-27 Identities = 70/171 (40%), Positives = 95/171 (55%), Gaps = 2/171 (1%) Frame = +3 Query: 54 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 233 ++ Y + +G G+FG K+ + +T VA+K + R ++E V REI R Sbjct: 1 MEKYEPVREIGAGNFGVAKLMRNKETRELVAMKFIERGN----RIDENVFREIVNHRSLR 56 Query: 234 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 413 HP+IIR EV+ + +VMEY GELF+ I E GR E EAR FFQQ++ GV YCH Sbjct: 57 HPNIIRFKEVVVTGRHLAIVMEYAAGGELFERICEAGRFHEDEARYFFQQLVCGVSYCHA 116 Query: 414 NMVVHRDLKPENLLLDNN--CDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 + HRDLK EN LLD + +KI DFG S K++ G+P Y A Sbjct: 117 MQICHRDLKLENTLLDGSPAPRLKICDFGYSKSSLLHSRPKSTVGTPAYIA 167
>AURKC_MOUSE (O88445) Serine/threonine-protein kinase 13 (EC 2.7.11.1)| (Aurora/Ipl1/Eg2 protein 1) (Aurora-C) Length = 282 Score = 119 bits (297), Expect = 8e-27 Identities = 61/167 (36%), Positives = 97/167 (58%) Frame = +3 Query: 54 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 233 + ++ IG+ LG G FG+V +A + VA+K+L + +I+ +E +++RE++I Sbjct: 13 INDFEIGRPLGRGKFGRVYLARLKENHFIVALKVLFKSEIEKEGLEHQLRREVEIQAHLQ 72 Query: 234 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 413 H +I+RLY IY+++EY GEL+ + +L +Q Q++ + YCH Sbjct: 73 HRNILRLYNYFYDDTRIYLILEYAPGGELYKELQRHQKLDQQRTATIIQELSDALTYCHE 132 Query: 414 NMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNY 554 V+HRD+KPENLLL N +VKI+DFG S V KT CG+ +Y Sbjct: 133 KKVIHRDIKPENLLLGLNGEVKISDFGWS-VHTPSLRRKTMCGTLDY 178
>KAPCA_CANFA (Q8MJ44) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 349 Score = 119 bits (297), Expect = 8e-27 Identities = 60/162 (37%), Positives = 99/162 (61%) Frame = +3 Query: 75 KTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPHIIRL 254 KTLG GSFG+V + +H +TG+ A+KIL+++K+ + E E +IL+ P +++L Sbjct: 46 KTLGTGSFGRVMLVKHKETGNHFAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKL 105 Query: 255 YEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMVVHRD 434 + +++Y+VMEYV GE+F ++ GR E AR + QI+ +Y H +++RD Sbjct: 106 EFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRD 165 Query: 435 LKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 LKPENLL+D +++ DFG + ++ + T CG+P Y A Sbjct: 166 LKPENLLIDQQGYIQVTDFGFAKRVKGRTW--TLCGTPEYLA 205
>KCC1G_HUMAN (Q96NX5) Calcium/calmodulin-dependent protein kinase type 1G (EC| 2.7.11.17) (CaM kinase IG) (CaM kinase I gamma) (CaMKI gamma) (CaMKI-gamma) (CaM-KI gamma) (CaMKIG) (CaMK-like CREB kinase III) (CLICK III) Length = 476 Score = 119 bits (297), Expect = 8e-27 Identities = 64/174 (36%), Positives = 101/174 (58%), Gaps = 3/174 (1%) Frame = +3 Query: 48 NPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRL 227 N K + + LG G+F +V + + TG A+K + + + ++ EI +L+ Sbjct: 18 NIRKTFIFMEVLGSGAFSEVFLVKQRLTGKLFALKCIKKSPAFR---DSSLENEIAVLKK 74 Query: 228 FMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYC 407 H +I+ L ++ E+ Y+VM+ V GELFD I+E+G E++A QQ++S V+Y Sbjct: 75 IKHENIVTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKYL 134 Query: 408 HRNMVVHRDLKPENLLL---DNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 H N +VHRDLKPENLL + N + I DFGLS + ++G + T+CG+P Y A Sbjct: 135 HENGIVHRDLKPENLLYLTPEENSKIMITDFGLSKMEQNG-IMSTACGTPGYVA 187
>TSSK3_HUMAN (Q96PN8) Testis-specific serine/threonine-protein kinase 3 (EC| 2.7.11.1) (TSSK-3) (Testis-specific kinase 3) (TSK-3) (Serine/threonine-protein kinase 22C) Length = 268 Score = 119 bits (297), Expect = 8e-27 Identities = 66/169 (39%), Positives = 104/169 (61%), Gaps = 3/169 (1%) Frame = +3 Query: 63 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 242 Y++GKT+G G++ KVK A K KVAIK++++ ++ + RE++I+R H + Sbjct: 10 YQLGKTIGEGTYSKVKEAFSKKHQRKVAIKVIDKMGGPEEFIQRFLPRELQIVRTLDHKN 69 Query: 243 IIRLYEVIE-APADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNM 419 II++YE++E A I +VME + G++FD ++ G L E A+ F+Q++ ++YCH Sbjct: 70 IIQVYEMLESADGKICLVMELAEGGDVFDCVLNGGPLPESRAKALFRQMVEAIRYCHGCG 129 Query: 420 VVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGH--FLKTSCGSPNYAA 560 V HRDLK EN LL ++K+ DFG + V+ H +T CGS YAA Sbjct: 130 VAHRDLKCENALL-QGFNLKLTDFGFAKVLPKSHRELSQTFCGSTAYAA 177
>KAPCB_PIG (P05383) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 119 bits (297), Expect = 8e-27 Identities = 64/182 (35%), Positives = 106/182 (58%) Frame = +3 Query: 15 RWKMEAGGKDGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEE 194 +W+ A G L+++ KTLG GSFG+V + +H T A+KIL+++K+ + E Sbjct: 29 KWENPAPNNAG--LEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIE 86 Query: 195 KVKREIKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRF 374 E +IL+ P ++RL + +++Y+VMEYV GE+F ++ GR E AR + Sbjct: 87 HTLNEKRILQAVNFPFLVRLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFY 146 Query: 375 FQQIISGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNY 554 QI+ +Y H +++RDLKPENLL+D+ +++ DFG + ++ + T CG+P Y Sbjct: 147 AAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTW--TLCGTPEY 204 Query: 555 AA 560 A Sbjct: 205 LA 206
>KAPCB_HUMAN (P22694) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 119 bits (297), Expect = 8e-27 Identities = 63/180 (35%), Positives = 105/180 (58%) Frame = +3 Query: 21 KMEAGGKDGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKV 200 K E ++ L+++ KTLG GSFG+V + +H T A+KIL+++K+ + E Sbjct: 29 KWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHT 88 Query: 201 KREIKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQ 380 E +IL+ P ++RL + +++Y+VMEYV GE+F ++ GR E AR + Sbjct: 89 LNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAA 148 Query: 381 QIISGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 QI+ +Y H +++RDLKPENLL+D+ +++ DFG + ++ + T CG+P Y A Sbjct: 149 QIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTW--TLCGTPEYLA 206
>KCC2D_RAT (P15791) Calcium/calmodulin-dependent protein kinase type II delta| chain (EC 2.7.11.17) (CaM-kinase II delta chain) (CaM kinase II delta subunit) (CaMK-II delta subunit) Length = 533 Score = 119 bits (297), Expect = 8e-27 Identities = 69/168 (41%), Positives = 97/168 (57%), Gaps = 4/168 (2%) Frame = +3 Query: 63 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 242 Y++ + LG G+F V+ I TG + A KI+N +K+ D +K++RE +I RL HP+ Sbjct: 14 YQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARD-HQKLEREARICRLLKHPN 72 Query: 243 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 422 I+RL++ I Y+V + V GELF+ IV + E +A QQI+ V +CH N + Sbjct: 73 IVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGI 132 Query: 423 VHRDLKPENLLL---DNNCDVKIADFGLS-NVMRDGHFLKTSCGSPNY 554 VHRDLKPENLLL VK+ADFGL+ V D G+P Y Sbjct: 133 VHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
>DCAK2_HUMAN (Q8N568) Serine/threonine-protein kinase DCAMKL2 (EC 2.7.11.1)| (Doublecortin-like and CAM kinase-like 2) Length = 766 Score = 119 bits (297), Expect = 8e-27 Identities = 66/173 (38%), Positives = 99/173 (57%), Gaps = 4/173 (2%) Frame = +3 Query: 54 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 233 L+ Y+IGK +G G+F VK TG + A+KI++ K K E ++ E+ ILR Sbjct: 391 LEKYKIGKVIGDGNFAVVKECIDRSTGKEFALKIID--KAKCCGKEHLIENEVSILRRVK 448 Query: 234 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 413 HP+II L E +E ++++VME VK G+LFD I + E++ + + ++Y H Sbjct: 449 HPNIIMLVEEMETATELFLVMELVKGGDLFDAITSSTKYTERDGSAMVYNLANALRYLHG 508 Query: 414 NMVVHRDLKPENLLL----DNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 +VHRD+KPENLL+ D +K+ DFGL+ V+ L T CG+P Y A Sbjct: 509 LSIVHRDIKPENLLVCEYPDGTKSLKLGDFGLATVVEGP--LYTVCGTPTYVA 559
>KCC1G_MOUSE (Q91VB2) Calcium/calmodulin-dependent protein kinase type 1G (EC| 2.7.11.17) (CaM kinase IG) (CaM kinase I gamma) (CaMKI gamma) (CaMKI-gamma) (CaM-KI gamma) (CaMKIG) (CaMK-like CREB kinase III) (CLICK III) Length = 477 Score = 118 bits (296), Expect = 1e-26 Identities = 64/174 (36%), Positives = 101/174 (58%), Gaps = 3/174 (1%) Frame = +3 Query: 48 NPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRL 227 N K + + LG G+F +V + + TG A+K + + + ++ EI +L+ Sbjct: 18 NIRKTFIFMEVLGSGAFSEVFLVKQRVTGKLFALKCIKKSPAFR---DSSLENEIAVLKR 74 Query: 228 FMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYC 407 H +I+ L ++ E+ Y+VM+ V GELFD I+E+G E++A QQ++S V+Y Sbjct: 75 IKHENIVTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKYL 134 Query: 408 HRNMVVHRDLKPENLLL---DNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 H N +VHRDLKPENLL + N + I DFGLS + ++G + T+CG+P Y A Sbjct: 135 HENGIVHRDLKPENLLYLTPEENSKIMITDFGLSKMEQNG-VMSTACGTPGYVA 187
>KCC1G_RAT (Q7TNJ7) Calcium/calmodulin-dependent protein kinase type 1G (EC| 2.7.11.17) (CaM kinase IG) (CaM kinase I gamma) (CaMKI gamma) (CaMKI-gamma) (CaM-KI gamma) (CaMKIG) (CaMK-like CREB kinase III) (CLICK III) Length = 476 Score = 118 bits (296), Expect = 1e-26 Identities = 64/174 (36%), Positives = 101/174 (58%), Gaps = 3/174 (1%) Frame = +3 Query: 48 NPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRL 227 N K + + LG G+F +V + + TG A+K + + + ++ EI +L+ Sbjct: 18 NIRKTFIFMEVLGSGAFSEVFLVKQRVTGKLFALKCIKKSPAFR---DSSLENEIAVLKR 74 Query: 228 FMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYC 407 H +I+ L ++ E+ Y+VM+ V GELFD I+E+G E++A QQ++S V+Y Sbjct: 75 IKHENIVTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKYL 134 Query: 408 HRNMVVHRDLKPENLLL---DNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 H N +VHRDLKPENLL + N + I DFGLS + ++G + T+CG+P Y A Sbjct: 135 HENGIVHRDLKPENLLYLTPEENSKIMITDFGLSKMEQNG-VMSTACGTPGYVA 187
>CHK1_MOUSE (O35280) Serine/threonine-protein kinase Chk1 (EC 2.7.11.1)| Length = 476 Score = 118 bits (296), Expect = 1e-26 Identities = 64/172 (37%), Positives = 106/172 (61%), Gaps = 3/172 (1%) Frame = +3 Query: 54 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 233 ++++ + +TLG G++G+V++A + T VA+KI++ ++ +D E +K+EI I ++ Sbjct: 6 VEDWDLVQTLGEGAYGEVQLAVNRITEEAVAVKIVDMKRA--IDCPENIKKEICINKMLS 63 Query: 234 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 413 H ++++ Y Y+ +EY GELFD I + EQ+A+RFF Q+++GV Y H Sbjct: 64 HENVVKFYGHRREGHIQYLFLEYCSGGELFDRIEPDIGMPEQDAQRFFHQLMAGVVYLHG 123 Query: 414 NMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGH---FLKTSCGSPNYAA 560 + HRD+KPENLLLD ++KI+DFGL+ V R + L CG+ Y A Sbjct: 124 IGITHRDIKPENLLLDERDNLKISDFGLATVFRHNNRERLLNKMCGTLPYVA 175
>KPSH1_BRARE (Q501V0) Serine/threonine-protein kinase H1 homolog (EC 2.7.11.1)| Length = 422 Score = 118 bits (295), Expect = 1e-26 Identities = 67/171 (39%), Positives = 97/171 (56%), Gaps = 5/171 (2%) Frame = +3 Query: 63 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 242 Y I +G GSF +V EH T AIK++ R + ++ E E+ +LR H + Sbjct: 96 YDIKALIGRGSFSRVVRVEHRSTRQPYAIKMIETRYREGREVCES---ELCVLRRVRHTN 152 Query: 243 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 422 II+L EV E +Y+VME GELFD I+ +G E++A R Q ++ GV+Y H + Sbjct: 153 IIQLMEVFETAERVYMVMELATGGELFDRIITRGSFTERDATRVLQMVLDGVKYLHTLGI 212 Query: 423 VHRDLKPENLLLDN---NCDVKIADFGLSNVMRDGH--FLKTSCGSPNYAA 560 HRDLKPENLL + + + I DFGL++ + G +KT+CG+P Y A Sbjct: 213 THRDLKPENLLYYHPGADSKIMITDFGLASTRKKGDECLMKTTCGTPEYIA 263
>CHK1_RAT (Q91ZN7) Serine/threonine-protein kinase Chk1 (EC 2.7.11.1)| Length = 476 Score = 118 bits (295), Expect = 1e-26 Identities = 64/172 (37%), Positives = 106/172 (61%), Gaps = 3/172 (1%) Frame = +3 Query: 54 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 233 ++++ + +TLG G++G+V++A + T VA+KI++ ++ +D E +K+EI I ++ Sbjct: 6 VEDWDLVQTLGEGAYGEVQLAVNRITEEAVAVKIVDMKRA--IDCPENIKKEICINKMLN 63 Query: 234 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 413 H ++++ Y Y+ +EY GELFD I + EQ+A+RFF Q+++GV Y H Sbjct: 64 HENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEQDAQRFFHQLMAGVVYLHG 123 Query: 414 NMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGH---FLKTSCGSPNYAA 560 + HRD+KPENLLLD ++KI+DFGL+ V R + L CG+ Y A Sbjct: 124 IGITHRDIKPENLLLDERDNLKISDFGLATVFRHNNRERLLNKMCGTLPYVA 175
>IPL1_CANGA (Q6FV07) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 358 Score = 118 bits (295), Expect = 1e-26 Identities = 59/167 (35%), Positives = 98/167 (58%) Frame = +3 Query: 54 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 233 LK++ +G+ LG G FGKV H K+G A+K + + +I ++ +++KRE+ I Sbjct: 97 LKDFEVGRKLGKGKFGKVYCVRHKKSGFICALKAIEKNEILQFNLLKQLKREVDIQLGMD 156 Query: 234 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 413 HP+II+LY +Y++ME+ +GEL+ + G + A + QI + Y H+ Sbjct: 157 HPNIIKLYAHFHDEKRVYLLMEHSINGELYKSLKNNGPFNDVLASHYIYQIADALHYMHK 216 Query: 414 NMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNY 554 ++HRD+KPEN+L+ + VK+ADFG S + +G KT CG+ +Y Sbjct: 217 KRIIHRDVKPENVLIGFDNVVKLADFGWSILNPEGSKRKTLCGTIDY 263
>ARK1_SCHPO (O59790) Serine/threonine-protein kinase ark1 (EC 2.7.11.1)| (Aurora-related kinase 1) Length = 355 Score = 118 bits (295), Expect = 1e-26 Identities = 60/164 (36%), Positives = 101/164 (61%) Frame = +3 Query: 63 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 242 + IGK LG G FG+V +A+ KTG VA+K L++ ++ +E++V+REI+I H + Sbjct: 89 FEIGKPLGKGKFGRVYLAKEKKTGFIVALKTLHKSELVQSKIEKQVRREIEIQSNLRHKN 148 Query: 243 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 422 I+RLY IY+++E+ GEL+ ++ R E+ A ++ Q+ + + Y H+ V Sbjct: 149 ILRLYGHFHDEKRIYLILEFAGRGELYQHLRRAKRFSEEVASKYIFQMANALSYLHKKHV 208 Query: 423 VHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNY 554 +HRD+KPEN+LL + ++K++DFG S V + T CG+ +Y Sbjct: 209 IHRDIKPENILLGIDGEIKLSDFGWS-VHAPSNRRTTLCGTLDY 251
>KCC2B_HUMAN (Q13554) Calcium/calmodulin-dependent protein kinase type II beta| chain (EC 2.7.11.17) (CaM-kinase II beta chain) (CaM kinase II beta subunit) (CaMK-II beta subunit) Length = 664 Score = 117 bits (294), Expect = 2e-26 Identities = 68/168 (40%), Positives = 99/168 (58%), Gaps = 4/168 (2%) Frame = +3 Query: 63 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 242 Y++ + +G G+F V+ + TGH+ A KI+N +K+ D +K++RE +I RL H + Sbjct: 14 YQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARD-HQKLEREARICRLLKHSN 72 Query: 243 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 422 I+RL++ I Y+V + V GELF+ IV + E +A QQI+ V +CH+ V Sbjct: 73 IVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGV 132 Query: 423 VHRDLKPENLLLDNNCD---VKIADFGLS-NVMRDGHFLKTSCGSPNY 554 VHRDLKPENLLL + C VK+ADFGL+ V D G+P Y Sbjct: 133 VHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
>KCC2A_DROME (Q00168) Calcium/calmodulin-dependent protein kinase type II alpha| chain (EC 2.7.11.17) (CaM-kinase II alpha chain) Length = 530 Score = 117 bits (294), Expect = 2e-26 Identities = 71/169 (42%), Positives = 98/169 (57%), Gaps = 4/169 (2%) Frame = +3 Query: 60 NYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHP 239 NY I + LG G+F VK TG + A KI+N +K+ D + K++RE +I R HP Sbjct: 13 NYDIKEELGKGAFSIVKRCVQKSTGFEFAAKIINTKKLTARDFQ-KLEREARICRKLHHP 71 Query: 240 HIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNM 419 +I+RL++ I+ Y+V + V GELF+ IV + E +A QQI+ V +CH+N Sbjct: 72 NIVRLHDSIQEENYHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVNHCHQNG 131 Query: 420 VVHRDLKPENLLLDNNCD---VKIADFGLS-NVMRDGHFLKTSCGSPNY 554 VVHRDLKPENLLL + VK+ADFGL+ V D G+P Y Sbjct: 132 VVHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDHQAWFGFAGTPGY 180
>KAPCB_RAT (P68182) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 117 bits (294), Expect = 2e-26 Identities = 61/169 (36%), Positives = 101/169 (59%) Frame = +3 Query: 54 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 233 L+++ KTLG GSFG+V + +H T A+KIL+++K+ + E E +IL+ Sbjct: 40 LEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVE 99 Query: 234 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 413 P ++RL + +++Y+VMEYV GE+F ++ GR E AR + QI+ +Y H Sbjct: 100 FPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHS 159 Query: 414 NMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 +++RDLKPENLL+D+ +++ DFG + ++ + T CG+P Y A Sbjct: 160 LDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTW--TLCGTPEYLA 206
>KAPCB_MOUSE (P68181) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 117 bits (294), Expect = 2e-26 Identities = 61/169 (36%), Positives = 101/169 (59%) Frame = +3 Query: 54 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 233 L+++ KTLG GSFG+V + +H T A+KIL+++K+ + E E +IL+ Sbjct: 40 LEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVE 99 Query: 234 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 413 P ++RL + +++Y+VMEYV GE+F ++ GR E AR + QI+ +Y H Sbjct: 100 FPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHS 159 Query: 414 NMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 +++RDLKPENLL+D+ +++ DFG + ++ + T CG+P Y A Sbjct: 160 LDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTW--TLCGTPEYLA 206
>KAPCB_CRIGR (P68180) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 117 bits (294), Expect = 2e-26 Identities = 61/169 (36%), Positives = 101/169 (59%) Frame = +3 Query: 54 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 233 L+++ KTLG GSFG+V + +H T A+KIL+++K+ + E E +IL+ Sbjct: 40 LEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVE 99 Query: 234 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 413 P ++RL + +++Y+VMEYV GE+F ++ GR E AR + QI+ +Y H Sbjct: 100 FPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHS 159 Query: 414 NMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 +++RDLKPENLL+D+ +++ DFG + ++ + T CG+P Y A Sbjct: 160 LDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTW--TLCGTPEYLA 206
>KAPCA_MOUSE (P05132) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 117 bits (294), Expect = 2e-26 Identities = 62/180 (34%), Positives = 105/180 (58%) Frame = +3 Query: 21 KMEAGGKDGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKV 200 K E ++ L + KTLG GSFG+V + +H ++G+ A+KIL+++K+ + E Sbjct: 29 KWETPSQNTAQLDQFDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHT 88 Query: 201 KREIKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQ 380 E +IL+ P +++L + +++Y+VMEYV GE+F ++ GR E AR + Sbjct: 89 LNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYAA 148 Query: 381 QIISGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 QI+ +Y H +++RDLKPENLL+D +++ DFG + ++ + T CG+P Y A Sbjct: 149 QIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTW--TLCGTPEYLA 206
>KCC2D_HUMAN (Q13557) Calcium/calmodulin-dependent protein kinase type II delta| chain (EC 2.7.11.17) (CaM-kinase II delta chain) (CaM kinase II delta subunit) (CaMK-II delta subunit) Length = 499 Score = 117 bits (294), Expect = 2e-26 Identities = 69/168 (41%), Positives = 96/168 (57%), Gaps = 4/168 (2%) Frame = +3 Query: 63 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 242 Y++ + LG G+F V+ I TG A KI+N +K+ D +K++RE +I RL HP+ Sbjct: 14 YQLFEELGKGAFSVVRRCMKIPTGQGYAAKIINTKKLSARD-HQKLEREARICRLLKHPN 72 Query: 243 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 422 I+RL++ I Y+V + V GELF+ IV + E +A QQI+ V +CH N + Sbjct: 73 IVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGI 132 Query: 423 VHRDLKPENLLL---DNNCDVKIADFGLS-NVMRDGHFLKTSCGSPNY 554 VHRDLKPENLLL VK+ADFGL+ V D G+P Y Sbjct: 133 VHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
>KCC2B_RAT (P08413) Calcium/calmodulin-dependent protein kinase type II beta| chain (EC 2.7.11.17) (CaM-kinase II beta chain) (CaM kinase II beta subunit) (CaMK-II beta subunit) Length = 542 Score = 117 bits (294), Expect = 2e-26 Identities = 68/168 (40%), Positives = 99/168 (58%), Gaps = 4/168 (2%) Frame = +3 Query: 63 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 242 Y++ + +G G+F V+ + TGH+ A KI+N +K+ D +K++RE +I RL H + Sbjct: 14 YQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARD-HQKLEREARICRLLKHSN 72 Query: 243 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 422 I+RL++ I Y+V + V GELF+ IV + E +A QQI+ V +CH+ V Sbjct: 73 IVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGV 132 Query: 423 VHRDLKPENLLLDNNCD---VKIADFGLS-NVMRDGHFLKTSCGSPNY 554 VHRDLKPENLLL + C VK+ADFGL+ V D G+P Y Sbjct: 133 VHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
>KCC2B_MOUSE (P28652) Calcium/calmodulin-dependent protein kinase type II beta| chain (EC 2.7.11.17) (CaM-kinase II beta chain) (CaM kinase II beta subunit) (CaMK-II beta subunit) Length = 542 Score = 117 bits (294), Expect = 2e-26 Identities = 68/168 (40%), Positives = 99/168 (58%), Gaps = 4/168 (2%) Frame = +3 Query: 63 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 242 Y++ + +G G+F V+ + TGH+ A KI+N +K+ D +K++RE +I RL H + Sbjct: 14 YQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARD-HQKLEREARICRLLKHSN 72 Query: 243 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 422 I+RL++ I Y+V + V GELF+ IV + E +A QQI+ V +CH+ V Sbjct: 73 IVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGV 132 Query: 423 VHRDLKPENLLLDNNCD---VKIADFGLS-NVMRDGHFLKTSCGSPNY 554 VHRDLKPENLLL + C VK+ADFGL+ V D G+P Y Sbjct: 133 VHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
>AURKB_HUMAN (Q96GD4) Serine/threonine-protein kinase 12 (EC 2.7.11.1) (Aurora-| and Ipl1-like midbody-associated protein 1) (AIM-1) (Aurora/IPL1-related kinase 2) (Aurora-related kinase 2) (STK-1) (Aurora-B) Length = 344 Score = 117 bits (294), Expect = 2e-26 Identities = 62/167 (37%), Positives = 96/167 (57%) Frame = +3 Query: 54 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 233 + ++ IG+ LG G FG V +A K+ VA+K+L + +I+ +E +++REI+I Sbjct: 74 IDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLH 133 Query: 234 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 413 HP+I+RLY IY+++EY GEL+ + + EQ +++ + YCH Sbjct: 134 HPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHG 193 Query: 414 NMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNY 554 V+HRD+KPENLLL ++KIADFG S V KT CG+ +Y Sbjct: 194 KKVIHRDIKPENLLLGLKGELKIADFGWS-VHAPSLRRKTMCGTLDY 239
>KAPCA_RAT (P27791) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 117 bits (293), Expect = 2e-26 Identities = 59/162 (36%), Positives = 99/162 (61%) Frame = +3 Query: 75 KTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPHIIRL 254 KTLG GSFG+V + +H ++G+ A+KIL+++K+ + E E +IL+ P +++L Sbjct: 47 KTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKL 106 Query: 255 YEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMVVHRD 434 + +++Y+VMEYV GE+F ++ GR E AR + QI+ +Y H +++RD Sbjct: 107 EFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRD 166 Query: 435 LKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 LKPENLL+D +++ DFG + ++ + T CG+P Y A Sbjct: 167 LKPENLLIDQQGYIQVTDFGFAKRVKGRTW--TLCGTPEYLA 206
>TSSK4_HUMAN (Q6SA08) Testis-specific serine/threonine-protein kinase 4 (EC| 2.7.11.1) (TSSK-4) (Testis-specific kinase 4) (TSK-4) (Serine/threonine-protein kinase 22E) Length = 328 Score = 117 bits (292), Expect = 3e-26 Identities = 60/181 (33%), Positives = 102/181 (56%), Gaps = 16/181 (8%) Frame = +3 Query: 63 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 242 Y +GK +G GS+G V A + K VA+KI++++K + + + + REI+++++ H + Sbjct: 25 YEVGKAIGHGSYGSVYEAFYTKQKVMVAVKIISKKKASDDYLNKFLPREIQVMKVLRHKY 84 Query: 243 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 422 +I Y IE+ + +Y+++E + G++ ++I G E A ++F Q+ G+ Y H + Sbjct: 85 LINFYRAIESTSRVYIILELAQGGDVLEWIQRYGACSEPLAGKWFSQLTLGIAYLHSKSI 144 Query: 423 VHRDLKPENLLLDNNCDVKIADFGLSNVMRD----------------GHFLKTSCGSPNY 554 VHRDLK ENLLLD +VKI+DFG + ++ H +T CGS Y Sbjct: 145 VHRDLKLENLLLDKWENVKISDFGFAKMVPSNQPVGCSPSYRQVNCFSHLSQTYCGSFAY 204 Query: 555 A 557 A Sbjct: 205 A 205
>STK6_MOUSE (P97477) Serine/threonine-protein kinase 6 (EC 2.7.11.1)| (Aurora-family kinase 1) (Aurora/IPL1-related kinase 1) (Ipl1- and aurora-related kinase 1) (Aurora-A) (Serine/threonine-protein kinase Ayk1) Length = 395 Score = 117 bits (292), Expect = 3e-26 Identities = 56/167 (33%), Positives = 100/167 (59%) Frame = +3 Query: 54 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 233 L+++ IG+ LG G FG V +A ++ +A+K+L + +++ ++E +++RE++I Sbjct: 121 LEDFDIGRPLGKGKFGNVYLARERQSKFILALKVLFKTQLEKANVEHQLRREVEIQSHLR 180 Query: 234 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 413 HP+I+RLY +Y+++EY G ++ + + + EQ + ++ + + YCH Sbjct: 181 HPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHS 240 Query: 414 NMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNY 554 V+HRD+KPENLLL +N ++KIADFG S V T CG+ +Y Sbjct: 241 KRVIHRDIKPENLLLGSNGELKIADFGWS-VHAPSSRRTTMCGTLDY 286
>TSSK4_MOUSE (Q9D411) Testis-specific serine/threonine-protein kinase 4 (EC| 2.7.11.1) (TSSK-4) (Testis-specific kinase 4) (TSK-4) Length = 328 Score = 116 bits (291), Expect = 4e-26 Identities = 60/181 (33%), Positives = 101/181 (55%), Gaps = 16/181 (8%) Frame = +3 Query: 63 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 242 Y +GK +G GS+G V A + K VA+KI++++K + + + REI+++++ H + Sbjct: 25 YEVGKIIGHGSYGTVYEAYYTKQKVMVAVKIISKKKASEDYLNKFLPREIQVMKVLRHKY 84 Query: 243 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 422 +I Y+ IE + +Y+++E + G++ ++I G E A ++F Q+ G+ Y H + Sbjct: 85 LINFYQAIETTSRVYIILELAQGGDVLEWIQRYGACAETLAGKWFSQMALGIAYLHSKGI 144 Query: 423 VHRDLKPENLLLDNNCDVKIADFGLSNVMRD----------------GHFLKTSCGSPNY 554 VHRDLK ENLLLD +VKI+DFG + ++ H +T CGS Y Sbjct: 145 VHRDLKLENLLLDKRENVKISDFGFAKMVPSSQPVHSSPSYRQMNSLSHLSQTYCGSFAY 204 Query: 555 A 557 A Sbjct: 205 A 205
>KDC2_DROME (P16912) Protein kinase DC2 (EC 2.7.11.1)| Length = 583 Score = 116 bits (291), Expect = 4e-26 Identities = 62/169 (36%), Positives = 99/169 (58%) Frame = +3 Query: 54 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 233 L +Y+I KT+G G+FG+V + + A+KIL ++ + E VK E ILR Sbjct: 271 LDDYQIIKTVGTGTFGRVCLCRDRISEKYCAMKILAMTEVIRLKQIEHVKNERNILREIR 330 Query: 234 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 413 HP +I L + +++Y++ +YV GELF Y+ G+ Q + + +I+S ++Y H Sbjct: 331 HPFVISLEWSTKDDSNLYMIFDYVCGGELFTYLRNAGKFTSQTSNFYAAEIVSALEYLHS 390 Query: 414 NMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 +V+RDLKPENLL++ + +KI DFG + +RD + T CG+P Y A Sbjct: 391 LQIVYRDLKPENLLINRDGHLKITDFGFAKKLRDRTW--TLCGTPEYIA 437
>KAPL_APLCA (P21901) Spermatozoon-associated protein kinase (EC 2.7.11.1) (SAK)| (C-APL-B) Length = 351 Score = 116 bits (291), Expect = 4e-26 Identities = 65/171 (38%), Positives = 99/171 (57%), Gaps = 2/171 (1%) Frame = +3 Query: 54 LKNYRIGKTLGIGSFGKVKIAEHIKTGHK--VAIKILNRRKIKNMDMEEKVKREIKILRL 227 ++NY + +TLG GSFG+V +++H + AIKILN+ K+ M E E +IL Sbjct: 39 IRNYTLIRTLGSGSFGRVMLSQHGGDNPQKCYAIKILNKEKVVKMKQVEHTMNEKRILLS 98 Query: 228 FMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYC 407 P ++R + ++Y+VME+V GELF + +KGRL E + Q+ +QY Sbjct: 99 IGSPFVVRCLNAFKDTTNLYMVMEFVNGGELFHLLRKKGRLPEYWCTFYAAQVTMALQYL 158 Query: 408 HRNMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 H +++RDLKPEN+LLD+ +K+ DFG ++ GH T CG+P Y A Sbjct: 159 HNCSLLYRDLKPENILLDHLGYLKVTDFGFDRRVQ-GH-TWTLCGTPQYLA 207
>KAPC_YEAST (P05986) cAMP-dependent protein kinase type 3 (EC 2.7.11.11) (PKA| 3) Length = 398 Score = 116 bits (290), Expect = 5e-26 Identities = 57/169 (33%), Positives = 96/169 (56%) Frame = +3 Query: 54 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 233 L +++I +TLG GSFG+V + G A+K L + I + E E ++L + Sbjct: 85 LSDFQILRTLGTGSFGRVHLIRSNHNGRFYALKTLKKHTIVKLKQVEHTNDERRMLSIVS 144 Query: 234 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 413 HP IIR++ + +++VM+Y++ GELF + + R A+ + ++ ++Y H Sbjct: 145 HPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHS 204 Query: 414 NMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 +++RDLKPEN+LLD N +KI DFG + + D + T CG+P+Y A Sbjct: 205 KDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVTY--TLCGTPDYIA 251
>CDPK1_PLAYO (Q7RAH3) Calcium-dependent protein kinase 1 (EC 2.7.11.1)| Length = 534 Score = 115 bits (289), Expect = 6e-26 Identities = 65/188 (34%), Positives = 112/188 (59%), Gaps = 14/188 (7%) Frame = +3 Query: 39 KDGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGH-KVAIKILNRRKI---------KNMD- 185 K+G ++Y + LG G++G+V + + K GH + AIK++ + + KN++ Sbjct: 48 KEGKIGESYFKVRKLGSGAYGEVLLCKE-KNGHSEKAIKVIKKSQFDKGRYNDDNKNIEK 106 Query: 186 MEEKVKREIKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEA 365 E++ EI +L+ HP+II+L++V E Y+V E+ + GELF+ I+ + + E +A Sbjct: 107 FHEEIYNEISLLKSLDHPNIIKLFDVFEDKKYFYLVTEFYEGGELFEQIINRHKFDECDA 166 Query: 366 RRFFQQIISGVQYCHRNMVVHRDLKPENLLLDNN---CDVKIADFGLSNVMRDGHFLKTS 536 +QI+SG+ Y H++ +VHRD+KPEN+LL+N ++KI DFGLS+ + L+ Sbjct: 167 ANIMKQILSGICYLHKHNIVHRDIKPENILLENKNSLLNIKIVDFGLSSFFSKDYKLRDR 226 Query: 537 CGSPNYAA 560 G+ Y A Sbjct: 227 LGTAYYIA 234
>STK6_RAT (P59241) Serine/threonine-protein kinase 6 (EC 2.7.11.1) (Aurora-A)| (ratAurA) Length = 397 Score = 115 bits (288), Expect = 8e-26 Identities = 59/178 (33%), Positives = 102/178 (57%) Frame = +3 Query: 21 KMEAGGKDGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKV 200 K E K L+++ IG+ LG G FG V +A ++ +A+K+L + +++ +E ++ Sbjct: 112 KTEDSKKRQWTLEDFDIGRPLGKGKFGNVYLAREKQSKFILALKVLFKVQLEKAGVEHQL 171 Query: 201 KREIKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQ 380 +RE++I HP+I+RLY +Y+++EY G ++ + + + EQ + Sbjct: 172 RREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYIT 231 Query: 381 QIISGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNY 554 ++ + + YCH V+HRD+KPENLLL +N ++KIADFG S V T CG+ +Y Sbjct: 232 ELANALSYCHSKRVIHRDIKPENLLLGSNGELKIADFGWS-VHAPSSRRTTLCGTLDY 288
>KAPA_YEAST (P06244) cAMP-dependent protein kinase type 1 (EC 2.7.11.11) (PKA| 1) (CDC25-suppressing protein kinase) (PK-25) Length = 397 Score = 115 bits (288), Expect = 8e-26 Identities = 56/169 (33%), Positives = 97/169 (57%) Frame = +3 Query: 54 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 233 L++++I +TLG GSFG+V + G A+K+L + + + E E +L + Sbjct: 84 LQDFQILRTLGTGSFGRVHLIRSRHNGRYYAMKVLKKEIVVRLKQVEHTNDERLMLSIVT 143 Query: 234 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 413 HP IIR++ + I+++M+Y++ GELF + + R A+ + ++ ++Y H Sbjct: 144 HPFIIRMWGTFQDAQQIFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHS 203 Query: 414 NMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 +++RDLKPEN+LLD N +KI DFG + + D + T CG+P+Y A Sbjct: 204 KDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVTY--TLCGTPDYIA 250
>CHK1_HUMAN (O14757) Serine/threonine-protein kinase Chk1 (EC 2.7.11.1)| Length = 476 Score = 115 bits (288), Expect = 8e-26 Identities = 63/172 (36%), Positives = 105/172 (61%), Gaps = 3/172 (1%) Frame = +3 Query: 54 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 233 ++++ + +TLG G++G+V++A + T VA+KI++ ++ +D E +K+EI I ++ Sbjct: 6 VEDWDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRA--VDCPENIKKEICINKMLN 63 Query: 234 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 413 H ++++ Y Y+ +EY GELFD I + E +A+RFF Q+++GV Y H Sbjct: 64 HENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHG 123 Query: 414 NMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGH---FLKTSCGSPNYAA 560 + HRD+KPENLLLD ++KI+DFGL+ V R + L CG+ Y A Sbjct: 124 IGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVA 175
>KAPC_DROME (P12370) cAMP-dependent protein kinase catalytic subunit (EC| 2.7.11.11) (PKA C) Length = 352 Score = 115 bits (288), Expect = 8e-26 Identities = 59/162 (36%), Positives = 97/162 (59%) Frame = +3 Query: 75 KTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPHIIRL 254 KTLG GSFG+V I +H T A+KIL+++K+ + E E +IL+ P ++ L Sbjct: 49 KTLGTGSFGRVMIVQHKPTKDYYAMKILDKQKVVKLKQVEHTLNEKRILQAIQFPFLVSL 108 Query: 255 YEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMVVHRD 434 + +++Y+V+EYV GE+F ++ + GR E +R + QI+ +Y H +++RD Sbjct: 109 RYHFKDNSNLYMVLEYVPGGEMFSHLRKVGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRD 168 Query: 435 LKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 LKPENLL+D+ +K+ DFG + ++ + T CG+P Y A Sbjct: 169 LKPENLLIDSQGYLKVTDFGFAKRVKGRTW--TLCGTPEYLA 208
>KCC1_METAN (O14408) Calcium/calmodulin-dependent protein kinase (EC 2.7.11.17)| Length = 382 Score = 115 bits (287), Expect = 1e-25 Identities = 67/170 (39%), Positives = 101/170 (59%), Gaps = 4/170 (2%) Frame = +3 Query: 63 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 242 Y+ G+TLG G++G V+ A+ KVAIKI+ ++ +K E+ V E+ +L+ HPH Sbjct: 23 YKFGRTLGAGTYGVVREADG--PSGKVAIKIILKKNVKGN--EKMVYAELDMLQRLTHPH 78 Query: 243 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 422 I++ + E+ Y+V + GELFD I ++G+ E +A + +QI++ V Y H N V Sbjct: 79 IVKFVDWFESRDKFYIVTQLATGGELFDRICDQGKFTEVDASQTIRQIMTAVDYLHDNDV 138 Query: 423 VHRDLKPENLLL---DNNCDVKIADFGLSNVMR-DGHFLKTSCGSPNYAA 560 VHRDLKPENLL D + D+ +ADFG++ + L T GS YAA Sbjct: 139 VHRDLKPENLLYVTRDPDSDLVLADFGITKTLDIKEETLTTMAGSFGYAA 188
>STK6_HUMAN (O14965) Serine/threonine-protein kinase 6 (EC 2.7.11.1)| (Serine/threonine kinase 15) (Aurora/IPL1-related kinase 1) (Aurora-related kinase 1) (hARK1) (Aurora-A) (Breast-tumor-amplified kinase) Length = 403 Score = 114 bits (285), Expect = 2e-25 Identities = 58/181 (32%), Positives = 103/181 (56%) Frame = +3 Query: 12 ARWKMEAGGKDGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDME 191 ++ K E K L+++ IG+ LG G FG V +A ++ +A+K+L + +++ +E Sbjct: 116 SKQKNEESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVE 175 Query: 192 EKVKREIKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARR 371 +++RE++I HP+I+RLY +Y+++EY G ++ + + + EQ Sbjct: 176 HQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTAT 235 Query: 372 FFQQIISGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPN 551 + ++ + + YCH V+HRD+KPENLLL + ++KIADFG S V T CG+ + Sbjct: 236 YITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS-VHAPSSRRTTLCGTLD 294 Query: 552 Y 554 Y Sbjct: 295 Y 295
>KAPC_CAEEL (P21137) cAMP-dependent protein kinase catalytic subunit (EC| 2.7.11.11) (PKA C) Length = 404 Score = 114 bits (285), Expect = 2e-25 Identities = 56/162 (34%), Positives = 99/162 (61%) Frame = +3 Query: 75 KTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPHIIRL 254 KTLG GSFG+V + +H ++G+ A+KIL+++K+ + E E +IL+ P ++ + Sbjct: 85 KTLGTGSFGRVMLVKHKQSGNYYAMKILDKQKVVKLKQVEHTLNEKRILQAIDFPFLVNM 144 Query: 255 YEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMVVHRD 434 + +++Y+V+E++ GE+F ++ GR E +R + QI+ +Y H +++RD Sbjct: 145 TFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRD 204 Query: 435 LKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 LKPENLL+D+ +KI DFG + ++ + T CG+P Y A Sbjct: 205 LKPENLLIDSTGYLKITDFGFAKRVKGRTW--TLCGTPEYLA 244
>STK33_HUMAN (Q9BYT3) Serine/threonine-protein kinase 33 (EC 2.7.11.1)| Length = 514 Score = 114 bits (285), Expect = 2e-25 Identities = 69/177 (38%), Positives = 99/177 (55%), Gaps = 11/177 (6%) Frame = +3 Query: 63 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 242 Y G+ LG GSFG V A +T K AIK +N+ K + ++ ++RE+ IL+ H H Sbjct: 116 YTFGRILGKGSFGIVIEATDKETETKWAIKKVNKEKAGSSAVK-LLEREVNILKSVKHEH 174 Query: 243 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 422 II L +V E P +Y+VME + GEL + + KG E E R Q + S + Y H N + Sbjct: 175 IIHLEQVFETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHNNDI 234 Query: 423 VHRDLKPENLLL------DN---NCDVKIADFGLS--NVMRDGHFLKTSCGSPNYAA 560 VHRDLK EN+++ DN N ++K+ DFGL+ R L+ +CG+P Y A Sbjct: 235 VHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQATCGTPIYMA 291
>SSP1_SCHPO (P50526) Serine/threonine-protein kinase ssp1 (EC 2.7.11.1)| Length = 652 Score = 114 bits (284), Expect = 2e-25 Identities = 62/164 (37%), Positives = 100/164 (60%), Gaps = 9/164 (5%) Frame = +3 Query: 54 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRR-------KIKNMDMEEKVKREI 212 + +Y I K LG G GKVK+ T +AIKI+ + + +EKV+REI Sbjct: 132 INHYEIIKELGRGMHGKVKLGRDTVTRELLAIKIIPKTERRPKLGRANASSQKEKVRREI 191 Query: 213 KILRLFMHPHIIRLYEVIEAPAD--IYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQI 386 IL+ +HP+++RL EVI+ P+ +Y+V+EY+ GE+ + L EAR++F+ + Sbjct: 192 AILKKCVHPNVVRLREVIDDPSSTKVYLVLEYMSGGEVPWTDCDSPVLSISEARQYFRDV 251 Query: 387 ISGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDG 518 + G++Y H ++HRD+KP NLLL+++ VKI+DFG+S + G Sbjct: 252 VLGLEYLHYQGIIHRDIKPANLLLNSSNCVKISDFGVSYIANAG 295
>PRKX_HUMAN (P51817) Serine/threonine-protein kinase PRKX (EC 2.7.11.1)| (Protein kinase PKX1) Length = 358 Score = 114 bits (284), Expect = 2e-25 Identities = 57/169 (33%), Positives = 95/169 (56%) Frame = +3 Query: 54 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 233 L+++ T+G G+FG+V + + H A+K+++ + + E+ V E +L+ Sbjct: 46 LQDFDTLATVGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRLKQEQHVHNEKSVLKEVS 105 Query: 234 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 413 HP +IRL+ +Y++MEYV GELF Y+ +GR + +II ++Y H Sbjct: 106 HPFLIRLFWTWHDERFLYMLMEYVPGGELFSYLRNRGRFSSTTGLFYSAEIICAIEYLHS 165 Query: 414 NMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 +V+RDLKPEN+LLD + +K+ DFG + + D + T CG+P Y A Sbjct: 166 KEIVYRDLKPENILLDRDGHIKLTDFGFAKKLVDRTW--TLCGTPEYLA 212
>CDPK1_PLAFK (P62343) Calcium-dependent protein kinase 1 (EC 2.7.11.1) (PfCPK)| (PfCDPK1) Length = 523 Score = 114 bits (284), Expect = 2e-25 Identities = 64/190 (33%), Positives = 109/190 (57%), Gaps = 16/190 (8%) Frame = +3 Query: 39 KDGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGH-KVAIKILNRRKIKNMD---------- 185 K+G ++Y + LG G++G+V + K GH + AIK++ + + M Sbjct: 47 KEGKIGESYFKVRKLGSGAYGEVLLCRE-KHGHGEKAIKVIKKSQFDKMKYSITNKIECD 105 Query: 186 --MEEKVKREIKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQ 359 + E++ EI +L+ HP+II+L++V E Y+V E+ + GELF+ I+ + + E Sbjct: 106 DKIHEEIYNEISLLKSLDHPNIIKLFDVFEDKKYFYLVTEFYEGGELFEQIINRHKFDEC 165 Query: 360 EARRFFQQIISGVQYCHRNMVVHRDLKPENLLLDNN---CDVKIADFGLSNVMRDGHFLK 530 +A +QI+SG+ Y H++ +VHRD+KPEN+LL+N ++KI DFGLS+ + L+ Sbjct: 166 DAANIMKQILSGICYLHKHNIVHRDIKPENILLENKHSLLNIKIVDFGLSSFFSKDNKLR 225 Query: 531 TSCGSPNYAA 560 G+ Y A Sbjct: 226 DRLGTAYYIA 235
>CDPK1_PLAF7 (P62344) Calcium-dependent protein kinase 1 (EC 2.7.11.1)| Length = 523 Score = 114 bits (284), Expect = 2e-25 Identities = 64/190 (33%), Positives = 109/190 (57%), Gaps = 16/190 (8%) Frame = +3 Query: 39 KDGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGH-KVAIKILNRRKIKNMD---------- 185 K+G ++Y + LG G++G+V + K GH + AIK++ + + M Sbjct: 47 KEGKIGESYFKVRKLGSGAYGEVLLCRE-KHGHGEKAIKVIKKSQFDKMKYSITNKIECD 105 Query: 186 --MEEKVKREIKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQ 359 + E++ EI +L+ HP+II+L++V E Y+V E+ + GELF+ I+ + + E Sbjct: 106 DKIHEEIYNEISLLKSLDHPNIIKLFDVFEDKKYFYLVTEFYEGGELFEQIINRHKFDEC 165 Query: 360 EARRFFQQIISGVQYCHRNMVVHRDLKPENLLLDNN---CDVKIADFGLSNVMRDGHFLK 530 +A +QI+SG+ Y H++ +VHRD+KPEN+LL+N ++KI DFGLS+ + L+ Sbjct: 166 DAANIMKQILSGICYLHKHNIVHRDIKPENILLENKHSLLNIKIVDFGLSSFFSKDNKLR 225 Query: 531 TSCGSPNYAA 560 G+ Y A Sbjct: 226 DRLGTAYYIA 235
>IPL1_YEAST (P38991) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) (Increase-in-ploidy protein 1) Length = 367 Score = 114 bits (284), Expect = 2e-25 Identities = 53/167 (31%), Positives = 97/167 (58%) Frame = +3 Query: 54 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 233 L ++ +GK LG G FGKV H TG+ A+K++ + +I +++++ +RE++I Sbjct: 101 LDDFELGKKLGKGKFGKVYCVRHRSTGYICALKVMEKEEIIKYNLQKQFRREVEIQTSLN 160 Query: 234 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 413 HP++ + Y +Y++MEY+ +GE++ + G + A + QI + + Y H+ Sbjct: 161 HPNLTKSYGYFHDEKRVYLLMEYLVNGEMYKLLRLHGPFNDILASDYIYQIANALDYMHK 220 Query: 414 NMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNY 554 ++HRD+KPEN+L+ N +K+ DFG S + + KT CG+ +Y Sbjct: 221 KNIIHRDIKPENILIGFNNVIKLTDFGWSIINPPENRRKTVCGTIDY 267
>KCC2_YEAST (P22517) Calcium/calmodulin-dependent protein kinase II (EC| 2.7.11.17) Length = 447 Score = 113 bits (283), Expect = 3e-25 Identities = 63/172 (36%), Positives = 98/172 (56%), Gaps = 5/172 (2%) Frame = +3 Query: 60 NYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDME-EKVKREIKILRLFMH 236 NY G+TLG GSFG V+ A + T VAIKIL ++ ++ +++ + + E+ IL+ H Sbjct: 46 NYIFGRTLGAGSFGVVRQARKLSTNEDVAIKILLKKALQGNNVQLQMLYEELSILQKLSH 105 Query: 237 PHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRN 416 P+I+ + E+ Y+V + GELFD I+ +G+ E +A QI+ V+Y H Sbjct: 106 PNIVSFKDWFESKDKFYIVTQLATGGELFDRILSRGKFTEVDAVEIIVQILGAVEYMHSK 165 Query: 417 MVVHRDLKPENLLL---DNNCDVKIADFGLSNVMR-DGHFLKTSCGSPNYAA 560 VVHRDLKPEN+L N + IADFG++ ++ + + + GS Y A Sbjct: 166 NVVHRDLKPENVLYVDKSENSPLVIADFGIAKQLKGEEDLIYKAAGSLGYVA 217
>KCC2A_RAT (P11275) Calcium/calmodulin-dependent protein kinase type II alpha| chain (EC 2.7.11.17) (CaM-kinase II alpha chain) (CaM kinase II alpha subunit) (CaMK-II alpha subunit) Length = 478 Score = 112 bits (281), Expect = 5e-25 Identities = 61/151 (40%), Positives = 92/151 (60%), Gaps = 3/151 (1%) Frame = +3 Query: 57 KNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMH 236 + Y++ + LG G+F V+ + G + A KI+N +K+ D +K++RE +I RL H Sbjct: 11 EEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARD-HQKLEREARICRLLKH 69 Query: 237 PHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRN 416 P+I+RL++ I Y++ + V GELF+ IV + E +A QQI+ V +CH+ Sbjct: 70 PNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQM 129 Query: 417 MVVHRDLKPENLLLDN---NCDVKIADFGLS 500 VVHRDLKPENLLL + VK+ADFGL+ Sbjct: 130 GVVHRDLKPENLLLASKLKGAAVKLADFGLA 160
>KCC2A_PONPY (Q5RCC4) Calcium/calmodulin-dependent protein kinase type II alpha| chain (EC 2.7.11.17) (CaM-kinase II alpha chain) (CaM kinase II alpha subunit) (CaMK-II alpha subunit) Length = 478 Score = 112 bits (281), Expect = 5e-25 Identities = 61/151 (40%), Positives = 92/151 (60%), Gaps = 3/151 (1%) Frame = +3 Query: 57 KNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMH 236 + Y++ + LG G+F V+ + G + A KI+N +K+ D +K++RE +I RL H Sbjct: 11 EEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARD-HQKLEREARICRLLKH 69 Query: 237 PHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRN 416 P+I+RL++ I Y++ + V GELF+ IV + E +A QQI+ V +CH+ Sbjct: 70 PNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQM 129 Query: 417 MVVHRDLKPENLLLDN---NCDVKIADFGLS 500 VVHRDLKPENLLL + VK+ADFGL+ Sbjct: 130 GVVHRDLKPENLLLASKLKGAAVKLADFGLA 160
>KCC2A_HUMAN (Q9UQM7) Calcium/calmodulin-dependent protein kinase type II alpha| chain (EC 2.7.11.17) (CaM-kinase II alpha chain) (CaM kinase II alpha subunit) (CaMK-II alpha subunit) Length = 478 Score = 112 bits (281), Expect = 5e-25 Identities = 61/151 (40%), Positives = 92/151 (60%), Gaps = 3/151 (1%) Frame = +3 Query: 57 KNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMH 236 + Y++ + LG G+F V+ + G + A KI+N +K+ D +K++RE +I RL H Sbjct: 11 EEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARD-HQKLEREARICRLLKH 69 Query: 237 PHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRN 416 P+I+RL++ I Y++ + V GELF+ IV + E +A QQI+ V +CH+ Sbjct: 70 PNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQM 129 Query: 417 MVVHRDLKPENLLLDN---NCDVKIADFGLS 500 VVHRDLKPENLLL + VK+ADFGL+ Sbjct: 130 GVVHRDLKPENLLLASKLKGAAVKLADFGLA 160
>PHKG1_HUMAN (Q16816) Phosphorylase b kinase gamma catalytic chain, skeletal| muscle isoform (EC 2.7.11.19) (Phosphorylase kinase gamma subunit 1) Length = 386 Score = 112 bits (280), Expect = 7e-25 Identities = 61/175 (34%), Positives = 99/175 (56%), Gaps = 7/175 (4%) Frame = +3 Query: 57 KNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNM------DMEEKVKREIKI 218 +NY + LG G V+ H T + A+K+++ + ++ E +E+ I Sbjct: 17 ENYEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEVDI 76 Query: 219 LRLFM-HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISG 395 LR HP+II+L + E ++V + +K GELFDY+ EK L E+E R+ + ++ Sbjct: 77 LRKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMRALLEV 136 Query: 396 VQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 + H+ +VHRDLKPEN+LLD+N ++K+ DFG S + G L+ CG+P+Y A Sbjct: 137 ICTLHKLNIVHRDLKPENILLDDNMNIKLTDFGFSCQLEPGERLREVCGTPSYLA 191
>ULK2_HUMAN (Q8IYT8) Serine/threonine-protein kinase ULK2 (EC 2.7.11.1)| (Unc-51-like kinase 2) Length = 1036 Score = 112 bits (280), Expect = 7e-25 Identities = 63/170 (37%), Positives = 93/170 (54%), Gaps = 10/170 (5%) Frame = +3 Query: 81 LGIGSFGKVKIAEHI-KTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPHIIRLY 257 +G G+F V H KT +VAIK +N++ + + + +EIKIL+ H +I+ LY Sbjct: 15 VGHGAFAVVFRGRHRQKTDWEVAIKSINKKNLSKSQI--LLGKEIKILKELQHENIVALY 72 Query: 258 EVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMVVHRDL 437 +V E P +++VMEY G+L DY+ KG L E R F QI + ++ H ++HRDL Sbjct: 73 DVQELPNSVFLVMEYCNGGDLADYLQAKGTLSEDTIRVFLHQIAAAMRILHSKGIIHRDL 132 Query: 438 KPENLLLD---------NNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 KP+N+LL + +KIADFG + + T CGSP Y A Sbjct: 133 KPQNILLSYANRRKSSVSGIRIKIADFGFARYLHSNMMAATLCGSPMYMA 182
>KCC1_EMENI (Q00771) Calcium/calmodulin-dependent protein kinase (EC 2.7.11.17)| (CMPK) Length = 414 Score = 112 bits (280), Expect = 7e-25 Identities = 63/170 (37%), Positives = 99/170 (58%), Gaps = 4/170 (2%) Frame = +3 Query: 63 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 242 YR G+TLG G++G V+ A+ + KVA+KI+ +R ++ E V E+ +L+ HPH Sbjct: 23 YRFGRTLGAGTYGIVREADC--SSGKVAVKIILKRNVRGN--ERMVYDELDLLQKLNHPH 78 Query: 243 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 422 I+ + E+ Y+V + GELFD I E G+ E++A + +Q++ V Y H+ + Sbjct: 79 IVHFVDWFESKDKFYIVTQLATGGELFDRICEYGKFTEKDASQTIRQVLDAVNYLHQRNI 138 Query: 423 VHRDLKPENLLL---DNNCDVKIADFGLSNVM-RDGHFLKTSCGSPNYAA 560 VHRDLKPENLL D + + +ADFG++ ++ L + GS YAA Sbjct: 139 VHRDLKPENLLYLTRDLDSQLVLADFGIAKMLDNPAEVLTSMAGSFGYAA 188
>IPL1_YARLI (Q6C3J2) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 371 Score = 112 bits (280), Expect = 7e-25 Identities = 57/167 (34%), Positives = 97/167 (58%) Frame = +3 Query: 54 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 233 L ++ IGK LG G FGKV + + KTG A+K + ++++ ++E++ +RE++I Sbjct: 96 LDDFEIGKALGKGKFGKVYLVKDKKTGFVSALKCMEKKELVEGNVEKQFRREVEIQSNLR 155 Query: 234 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 413 H +++RL+ +Y+++EYV GEL+ + + R E A + Q+ + Y H Sbjct: 156 HTNVLRLFGHFHDKDRVYLILEYVVHGELYKLLRNQKRFTESTASSYIYQMSEALLYLHG 215 Query: 414 NMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNY 554 ++HRD+KPEN+LL N +KI+DFG S V + T CG+ +Y Sbjct: 216 KNIIHRDIKPENILLHFNDTIKISDFGWS-VHAPSNRRSTLCGTMDY 261
>ULK2_MOUSE (Q9QY01) Serine/threonine-protein kinase ULK2 (EC 2.7.11.1)| (Unc-51-like kinase 2) (Serine/threonine-protein kinase Unc51.2) Length = 1037 Score = 112 bits (280), Expect = 7e-25 Identities = 63/170 (37%), Positives = 93/170 (54%), Gaps = 10/170 (5%) Frame = +3 Query: 81 LGIGSFGKVKIAEHI-KTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPHIIRLY 257 +G G+F V H KT +VAIK +N++ + + + +EIKIL+ H +I+ LY Sbjct: 15 VGHGAFAVVFRGRHRQKTDWEVAIKSINKKNLSKSQI--LLGKEIKILKELQHENIVALY 72 Query: 258 EVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMVVHRDL 437 +V E P +++VMEY G+L DY+ KG L E R F QI + ++ H ++HRDL Sbjct: 73 DVQELPNSVFLVMEYCNGGDLADYLQAKGTLSEDTIRVFLHQIAAAMRILHSKGIIHRDL 132 Query: 438 KPENLLLD---------NNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 KP+N+LL + +KIADFG + + T CGSP Y A Sbjct: 133 KPQNILLSYANRRKSNVSGIRIKIADFGFARYLHSNTMAATLCGSPMYMA 182
>PHKG1_RAT (P13286) Phosphorylase b kinase gamma catalytic chain, skeletal| muscle isoform (EC 2.7.11.19) (Phosphorylase kinase gamma subunit 1) Length = 387 Score = 112 bits (279), Expect = 9e-25 Identities = 63/178 (35%), Positives = 102/178 (57%), Gaps = 7/178 (3%) Frame = +3 Query: 48 NPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRR------KIKNMDMEEKVKRE 209 N +NY + LG G V+ H T + A+KI++ + ++ E +E Sbjct: 14 NFYENYEPKEILGRGVSSVVRRCIHKPTCQEYAVKIIDITGGGSFSSEEVQELREATLKE 73 Query: 210 IKIL-RLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQI 386 + IL ++ HP+II+L + E ++V + +K GELFDY+ EK L E+E R+ + + Sbjct: 74 VDILQKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLTEKETRKIMRAL 133 Query: 387 ISGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 + V H+ +VHRDLKPEN+LLD+N ++K+ DFG S ++ G L+ CG+P+Y A Sbjct: 134 LEVVCTLHKLNIVHRDLKPENILLDDNMNIKLTDFGFSCQLQPGEKLREVCGTPSYLA 191
>YP150_YEAST (Q12152) Putative serine/threonine-protein kinase YPL150W (EC| 2.7.11.1) Length = 901 Score = 111 bits (278), Expect = 1e-24 Identities = 63/167 (37%), Positives = 90/167 (53%) Frame = +3 Query: 60 NYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHP 239 NY+I K +G GSFGKV +A H T KV +K ++ + + RE+ R F P Sbjct: 40 NYKILKQIGEGSFGKVYLALHRPTHRKVCLKTSDKN-------DPNIVREVFYHRQFDFP 92 Query: 240 HIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNM 419 +I +LYEVI + +++ +EY EL+D+++ R+ E F QI V Y H Sbjct: 93 YITKLYEVIVTESKVWMALEYCPGKELYDHLLSLRRISLLECGELFAQISGAVYYAHSMH 152 Query: 420 VVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 VHRDLK EN+LLD N + K+ DFG + L+T CG+ Y A Sbjct: 153 CVHRDLKLENILLDKNGNAKLTDFGFTRECMTKTTLETVCGTTVYMA 199
>TSSK6_MOUSE (Q925K9) Testis-specific serine/threonine-protein kinase 6 (EC| 2.7.11.1) (TSSK-6) (Small serine/threonine kinase) (Serine/threonine-protein kinase SSTK) Length = 273 Score = 111 bits (277), Expect = 2e-24 Identities = 67/169 (39%), Positives = 98/169 (57%), Gaps = 3/169 (1%) Frame = +3 Query: 63 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 242 Y++G+T+G GS+ KVK+A K VAIK+++RR+ + + + RE+ ILR HPH Sbjct: 12 YKLGRTIGEGSYSKVKVATSKKYKGTVAIKVVDRRRAPPDFVNKFLPRELSILRGVRHPH 71 Query: 243 IIRLYEVIEA-PADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNM 419 I+ ++E IE +Y+VME + +L + GR+ +AR F QI V+Y H + Sbjct: 72 IVHVFEFIEVCNGKLYIVMEAAAT-DLLQAVQRNGRIPGSQARELFSQIAGAVRYLHDHH 130 Query: 420 VVHRDLKPENLLLD-NNCDVKIADFGLSNVMRDGHFLKTS-CGSPNYAA 560 +VHRDLK EN+LL + VKI DFG L T+ CGS YA+ Sbjct: 131 LVHRDLKCENVLLSPDERRVKITDFGFGRQAHGYPDLSTTYCGSAAYAS 179
>CDPK_SOYBN (P28583) Calcium-dependent protein kinase SK5 (EC 2.7.11.1) (CDPK)| Length = 508 Score = 111 bits (277), Expect = 2e-24 Identities = 65/170 (38%), Positives = 93/170 (54%), Gaps = 4/170 (2%) Frame = +3 Query: 63 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILR-LFMHP 239 Y +G+ LG G FG +G K A K + +RK+ + E V REI+I+ L H Sbjct: 34 YEVGRKLGQGQFGTTFECTRRASGGKFACKSIPKRKLLCKEDYEDVWREIQIMHHLSEHA 93 Query: 240 HIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNM 419 +++R+ E +++VME + GELFD IV+KG E++A R + I+ V+ CH Sbjct: 94 NVVRIEGTYEDSTAVHLVMELCEGGELFDRIVQKGHYSERQAARLIKTIVEVVEACHSLG 153 Query: 420 VVHRDLKPENLL---LDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 V+HRDLKPEN L +D + +K DFGLS + G GSP Y A Sbjct: 154 VMHRDLKPENFLFDTIDEDAKLKATDFGLSVFYKPGESFCDVVGSPYYVA 203
>PRKY_HUMAN (O43930) Serine/threonine-protein kinase PRKY (EC 2.7.11.1)| Length = 277 Score = 111 bits (277), Expect = 2e-24 Identities = 55/161 (34%), Positives = 89/161 (55%) Frame = +3 Query: 78 TLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPHIIRLY 257 T+G G+FG+V + + H A+K+++ + E+ V E +L+ HP +IRL+ Sbjct: 54 TMGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRRKQEQHVHNEKSVLKEVSHPFLIRLF 113 Query: 258 EVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMVVHRDL 437 +Y++MEYV GELF Y+ +G + +II ++Y H +V+RDL Sbjct: 114 WTWHEERFLYMLMEYVPGGELFSYLRNRGHFSSTTGLFYSAEIICAIEYLHSKEIVYRDL 173 Query: 438 KPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 KPEN+LLD + +K+ DFG + + D + T CG+P Y A Sbjct: 174 KPENILLDRDGHIKLTDFGFAKKLVDRTW--TLCGTPEYLA 212
>PHKG1_MOUSE (P07934) Phosphorylase b kinase gamma catalytic chain, skeletal| muscle isoform (EC 2.7.11.19) (Phosphorylase kinase gamma subunit 1) Length = 387 Score = 111 bits (277), Expect = 2e-24 Identities = 61/175 (34%), Positives = 101/175 (57%), Gaps = 7/175 (4%) Frame = +3 Query: 57 KNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRR------KIKNMDMEEKVKREIKI 218 +NY + LG G V+ H T + A+KI++ + ++ E +E+ I Sbjct: 17 ENYEPKEILGRGVSSVVRRCIHKPTCQEYAVKIIDITGGGSFSSEEVQELREATLKEVDI 76 Query: 219 L-RLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISG 395 L ++ HP+II+L + E ++V + +K GELFDY+ EK L E+E R+ + ++ Sbjct: 77 LQKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLTEKETRKIMRALLEV 136 Query: 396 VQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 + H+ +VHRDLKPEN+LLD+N ++K+ DFG S ++ G L+ CG+P+Y A Sbjct: 137 ICTLHKLNIVHRDLKPENILLDDNMNIKLTDFGFSCQLQPGEKLREVCGTPSYLA 191
>CDPK2_MAIZE (P49101) Calcium-dependent protein kinase 2 (EC 2.7.11.1) (CDPK 2)| Length = 513 Score = 111 bits (277), Expect = 2e-24 Identities = 63/170 (37%), Positives = 94/170 (55%), Gaps = 4/170 (2%) Frame = +3 Query: 63 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILR-LFMHP 239 Y GK LG G FG + I +G + A K +++RK+ + E ++REI+I++ L P Sbjct: 65 YSFGKELGRGQFGVTYLCTEIASGRQYACKSISKRKLVSKADREDIRREIQIMQHLSGQP 124 Query: 240 HIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNM 419 +I+ E ++++VVME GELFD I+ KG E+ A + +++ V CH Sbjct: 125 NIVEFRGAYEDKSNVHVVMELCAGGELFDRIIAKGHYTERAAATICRAVVNVVNICHFMG 184 Query: 420 VVHRDLKPENLLL---DNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 V+HRDLKPEN LL + N +K DFGLS + +G + GS Y A Sbjct: 185 VMHRDLKPENFLLATMEENAMLKATDFGLSVFIEEGKMYRDIVGSAYYVA 234
>IPL1_DEBHA (Q6BVA0) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 412 Score = 110 bits (276), Expect = 2e-24 Identities = 55/169 (32%), Positives = 96/169 (56%), Gaps = 2/169 (1%) Frame = +3 Query: 54 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 233 L ++ IGK LG G GKV +H +G+ A+K++ ++ + ++ +E+ +REI+I + Sbjct: 145 LDDFEIGKVLGKGKLGKVYCVKHKTSGYIAALKVMAKKDLIDLKLEKNFRREIEIQSNLI 204 Query: 234 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 413 HP I RLY ++Y+++EY GEL+ ++ + R + A + Q+ + Y H Sbjct: 205 HPKISRLYGFFYDHKNVYLILEYSIHGELYHHLKVQRRFNDATASHYIYQVALALDYLHT 264 Query: 414 NMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLK--TSCGSPNY 554 ++HRD+KPEN+LL + +K++DFG S K T CG+ +Y Sbjct: 265 KHIIHRDIKPENILLSTDNCIKLSDFGWSVKSLPSSSTKRLTICGTLDY 313
>KCC2A_MOUSE (P11798) Calcium/calmodulin-dependent protein kinase type II alpha| chain (EC 2.7.11.17) (CaM-kinase II alpha chain) (CaM kinase II alpha subunit) (CaMK-II alpha subunit) Length = 478 Score = 110 bits (276), Expect = 2e-24 Identities = 60/151 (39%), Positives = 91/151 (60%), Gaps = 3/151 (1%) Frame = +3 Query: 57 KNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMH 236 + Y++ + LG G+F V+ + G + KI+N +K+ D +K++RE +I RL H Sbjct: 11 EEYQLFEELGKGAFSVVRRCVKVLAGQEYPAKIINTKKLSARD-HQKLEREARICRLLKH 69 Query: 237 PHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRN 416 P+I+RL++ I Y++ + V GELF+ IV + E +A QQI+ V +CH+ Sbjct: 70 PNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQM 129 Query: 417 MVVHRDLKPENLLLDN---NCDVKIADFGLS 500 VVHRDLKPENLLL + VK+ADFGL+ Sbjct: 130 GVVHRDLKPENLLLASKLKGAAVKLADFGLA 160
>CDPK2_PLAF7 (Q8ICR0) Calcium-dependent protein kinase 2 (EC 2.7.11.1) (PfCDPK2)| Length = 508 Score = 110 bits (275), Expect = 3e-24 Identities = 67/169 (39%), Positives = 94/169 (55%), Gaps = 3/169 (1%) Frame = +3 Query: 63 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 242 Y I + LG G++G V T AIK + ++KN++ + +EI+I++ HP+ Sbjct: 71 YIIDEKLGQGTYGCVYKGIDKVTNQLYAIKEEKKDRLKNIN---RFFQEIEIMKKLDHPN 127 Query: 243 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 422 I++LYE E IY++ME ELFD I+E G E+ A +QI S + Y H + Sbjct: 128 IVKLYETYENDNYIYLIMELCSGRELFDSIIENGSFTEKNAATIMKQIFSAIFYLHSLNI 187 Query: 423 VHRDLKPENLLLDN-NCD--VKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 VHRDLKPEN L + N D +KI DFGLS + G F T G+P Y A Sbjct: 188 VHRDLKPENFLFQSENKDSLLKIIDFGLSKNLGTGEFTTTKAGTPYYVA 236
>CDPK1_ORYSA (P53682) Calcium-dependent protein kinase, isoform 1 (EC 2.7.11.1)| (CDPK 1) Length = 534 Score = 110 bits (275), Expect = 3e-24 Identities = 65/180 (36%), Positives = 97/180 (53%), Gaps = 4/180 (2%) Frame = +3 Query: 33 GGKDGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREI 212 G K N + Y +G+ LG G FGK + I TG + A K + + ++ + E V+REI Sbjct: 63 GYKTPNVRELYTLGRELGQGQFGKTYLCTEISTGCQYACKTILKSNLRCVSDIEDVRREI 122 Query: 213 KILR-LFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQII 389 +I+ L +I+ + + E +++VME GELF I ++G E++A + I+ Sbjct: 123 QIMHHLSGQKNIVTIKDTYEDEQAVHIVMELCAGGELFSKIQKRGHYSERKAAELIKIIV 182 Query: 390 SGVQYCHRNMVVHRDLKPENLLL---DNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 ++ CH + V+HRDLKPEN LL D+ VK DFGLS R G + GSP Y A Sbjct: 183 GIIETCHSHGVMHRDLKPENFLLLDADDEFSVKAIDFGLSVFFRPGQVFREVVGSPYYIA 242
>POLO_DROME (P52304) Serine/threonine-protein kinase polo (EC 2.7.11.21)| Length = 576 Score = 110 bits (275), Expect = 3e-24 Identities = 62/174 (35%), Positives = 95/174 (54%), Gaps = 1/174 (0%) Frame = +3 Query: 42 DGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKIL 221 D N K Y+ + G G F K ++T A KI++++ + + +EK +EI I Sbjct: 18 DINQRKTYKRMRFFGKGGFAKCYEIIDVETDDVFAGKIVSKKLMIKHNQKEKTAQEITIH 77 Query: 222 RLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQ 401 R HP+I++ + E +IY+V+E K + + + + E E R + QII GV+ Sbjct: 78 RSLNHPNIVKFHNYFEDSQNIYIVLELCKKRSMMELHKRRKSITEFECRYYIYQIIQGVK 137 Query: 402 YCHRNMVVHRDLKPENLLLDNNCDVKIADFGL-SNVMRDGHFLKTSCGSPNYAA 560 Y H N ++HRDLK NL L++ VKI DFGL + + +G KT CG+PNY A Sbjct: 138 YLHDNRIIHRDLKLGNLFLNDLLHVKIGDFGLATRIEYEGERKKTLCGTPNYIA 191
>KAPB_SCHPO (P40376) cAMP-dependent protein kinase catalytic subunit (EC| 2.7.11.11) Length = 512 Score = 110 bits (275), Expect = 3e-24 Identities = 61/174 (35%), Positives = 98/174 (56%) Frame = +3 Query: 39 KDGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKI 218 KD ++++ +TLG GSFG+V + + AIK+L ++KI +M E E I Sbjct: 193 KDRYGIQDFNFLQTLGTGSFGRVHLVQSNHNRLYYAIKVLEKKKIVDMKQIEHTCDERYI 252 Query: 219 LRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGV 398 L HP I L+ + ++++VM++ + GELF + + R E+ A+ + ++I + Sbjct: 253 LSRVQHPFITILWGTFQDAKNLFMVMDFAEGGELFSLLRKCHRFPEKVAKFYAAEVILAL 312 Query: 399 QYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 Y H N +V+RDLKPENLLLD +KI DFG + + + T CG+P+Y A Sbjct: 313 DYLHHNQIVYRDLKPENLLLDRFGHLKIVDFGFAKRVSTSNCC-TLCGTPDYLA 365
>CDPK2_PLAFK (O15865) Calcium-dependent protein kinase 2 (EC 2.7.11.1) (PfCDPK2)| Length = 512 Score = 110 bits (275), Expect = 3e-24 Identities = 67/169 (39%), Positives = 94/169 (55%), Gaps = 3/169 (1%) Frame = +3 Query: 63 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 242 Y I + LG G++G V T AIK + ++KN++ + +EI+I++ HP+ Sbjct: 71 YIIDEKLGQGTYGCVYKGIDKVTNQLYAIKEEKKDRLKNIN---RFFQEIEIMKKLDHPN 127 Query: 243 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 422 I++LYE E IY++ME ELFD I+E G E+ A +QI S + Y H + Sbjct: 128 IVKLYETYENDNYIYLIMELCSGRELFDSIIENGSFTEKNAATIMKQIFSAIFYLHSLNI 187 Query: 423 VHRDLKPENLLLDN-NCD--VKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 VHRDLKPEN L + N D +KI DFGLS + G F T G+P Y A Sbjct: 188 VHRDLKPENFLFQSENKDSLLKIIDFGLSKNLGTGEFTTTKAGTPYYVA 236
>PLK1_MOUSE (Q07832) Serine/threonine-protein kinase PLK1 (EC 2.7.11.21)| (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13) Length = 603 Score = 110 bits (275), Expect = 3e-24 Identities = 64/174 (36%), Positives = 91/174 (52%), Gaps = 1/174 (0%) Frame = +3 Query: 42 DGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKIL 221 D + Y G+ LG G F K T A KI+ + + +EK+ EI I Sbjct: 46 DPRSRRQYVRGRFLGKGGFAKCFEISDADTKEVFAGKIVPKSLLLKPHQKEKMSMEISIH 105 Query: 222 RLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQ 401 R H H++ ++ E ++VV+E + L + + L E EAR + +QI+ G Q Sbjct: 106 RSLAHQHVVGFHDFFEDSDFVFVVLELCRRRSLLELHKRRKALTEPEARYYLRQIVLGCQ 165 Query: 402 YCHRNMVVHRDLKPENLLLDNNCDVKIADFGL-SNVMRDGHFLKTSCGSPNYAA 560 Y HRN V+HRDLK NL L+ + +VKI DFGL + V +G KT CG+PNY A Sbjct: 166 YLHRNQVIHRDLKLGNLFLNEDLEVKIGDFGLATKVEYEGERKKTLCGTPNYIA 219
>CDPK_DAUCA (P28582) Calcium-dependent protein kinase (EC 2.7.11.1) (CDPK)| Length = 532 Score = 110 bits (274), Expect = 4e-24 Identities = 66/170 (38%), Positives = 94/170 (55%), Gaps = 4/170 (2%) Frame = +3 Query: 63 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILR-LFMHP 239 Y +GK LG G FG V +G A K + +RK+ + + +E +KREI+IL+ L P Sbjct: 81 YTLGKELGRGQFGCVYQCTENSSGQLYACKSILKRKLVSKNDKEDIKREIQILQHLSGQP 140 Query: 240 HIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNM 419 +I+ V E +++VME GELFD I+ +G E+ A +QI++ V CH Sbjct: 141 NIVEFKGVFEDRQSVHLVMELCAGGELFDRIIAQGHYSERAAATICRQIVNVVHVCHFMG 200 Query: 420 VVHRDLKPENLLL---DNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 V+HRDLKPEN LL D + +K DFGLS + +G + GS Y A Sbjct: 201 VMHRDLKPENFLLSSKDKDAMLKATDFGLSVFIEEGKVYRNIVGSAYYVA 250
>PDPK1_HUMAN (O15530) 3-phosphoinositide-dependent protein kinase 1 (EC| 2.7.11.1) (hPDK1) Length = 556 Score = 109 bits (272), Expect = 6e-24 Identities = 54/151 (35%), Positives = 86/151 (56%) Frame = +3 Query: 57 KNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMH 236 ++++ GK LG GSF V +A + T + AIKIL +R I + V RE ++ H Sbjct: 80 EDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDH 139 Query: 237 PHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRN 416 P ++LY + +Y + Y K+GEL YI + G E R + +I+S ++Y H Sbjct: 140 PFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGK 199 Query: 417 MVVHRDLKPENLLLDNNCDVKIADFGLSNVM 509 ++HRDLKPEN+LL+ + ++I DFG + V+ Sbjct: 200 GIIHRDLKPENILLNEDMHIQITDFGTAKVL 230
>PHKG1_RABIT (P00518) Phosphorylase b kinase gamma catalytic chain, skeletal| muscle isoform (EC 2.7.11.19) (Phosphorylase kinase gamma subunit 1) Length = 386 Score = 109 bits (272), Expect = 6e-24 Identities = 61/175 (34%), Positives = 99/175 (56%), Gaps = 7/175 (4%) Frame = +3 Query: 57 KNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRR------KIKNMDMEEKVKREIKI 218 +NY + LG G V+ H T + A+KI++ + ++ E +E+ I Sbjct: 17 ENYEPKEILGRGVSSVVRRCIHKPTCKEYAVKIIDVTGGGSFSAEEVQELREATLKEVDI 76 Query: 219 LRLFM-HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISG 395 LR HP+II+L + E ++V + +K GELFDY+ EK L E+E R+ + ++ Sbjct: 77 LRKVSGHPNIIQLKDTYETNTFFFLVFDLMKKGELFDYLTEKVTLSEKETRKIMRALLEV 136 Query: 396 VQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 + H+ +VHRDLKPEN+LLD++ ++K+ DFG S + G L+ CG+P+Y A Sbjct: 137 ICALHKLNIVHRDLKPENILLDDDMNIKLTDFGFSCQLDPGEKLREVCGTPSYLA 191
>PDPK1_RAT (O55173) 3-phosphoinositide-dependent protein kinase 1 (EC| 2.7.11.1) (Protein kinase B kinase) (PkB kinase) Length = 559 Score = 109 bits (272), Expect = 6e-24 Identities = 54/151 (35%), Positives = 86/151 (56%) Frame = +3 Query: 57 KNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMH 236 ++++ GK LG GSF V +A + T + AIKIL +R I + V RE ++ H Sbjct: 83 EDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDH 142 Query: 237 PHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRN 416 P ++LY + +Y + Y K+GEL YI + G E R + +I+S ++Y H Sbjct: 143 PFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGK 202 Query: 417 MVVHRDLKPENLLLDNNCDVKIADFGLSNVM 509 ++HRDLKPEN+LL+ + ++I DFG + V+ Sbjct: 203 GIIHRDLKPENILLNEDMHIQITDFGTAKVL 233
>PDPK1_MOUSE (Q9Z2A0) 3-phosphoinositide-dependent protein kinase 1 (EC| 2.7.11.1) (mPDK1) Length = 559 Score = 109 bits (272), Expect = 6e-24 Identities = 54/151 (35%), Positives = 86/151 (56%) Frame = +3 Query: 57 KNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMH 236 ++++ GK LG GSF V +A + T + AIKIL +R I + V RE ++ H Sbjct: 83 EDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDH 142 Query: 237 PHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRN 416 P ++LY + +Y + Y K+GEL YI + G E R + +I+S ++Y H Sbjct: 143 PFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGK 202 Query: 417 MVVHRDLKPENLLLDNNCDVKIADFGLSNVM 509 ++HRDLKPEN+LL+ + ++I DFG + V+ Sbjct: 203 GIIHRDLKPENILLNEDMHIQITDFGTAKVL 233
>PRKX_MOUSE (Q922R0) Serine/threonine-protein kinase PRKX (EC 2.7.11.1)| (PKA-related protein kinase) Length = 355 Score = 109 bits (272), Expect = 6e-24 Identities = 59/175 (33%), Positives = 101/175 (57%), Gaps = 1/175 (0%) Frame = +3 Query: 39 KDGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKV-AIKILNRRKIKNMDMEEKVKREIK 215 K G+ L+++ T+G G+FG+V + + KTG + A+KI++ + + E+ V+ E Sbjct: 38 KAGHSLQDWDTIATVGTGTFGRVNLVKE-KTGRQYCALKIMSIPDVIRLKQEQHVQNEKA 96 Query: 216 ILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISG 395 +L+ HP +I+L +Y++ME+V GELF Y+ +GR + + +I+ Sbjct: 97 VLKEINHPFLIKLLWTGHDNRFLYMLMEFVPGGELFTYLRNRGRFSSVASVFYATEIVCA 156 Query: 396 VQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 ++Y H +V+RDLKPEN+LLD +K+ DFG + + D + T CG+P Y A Sbjct: 157 IEYLHSKEIVYRDLKPENILLDREGHIKLTDFGFAKKLVDRTW--TLCGTPEYLA 209
>CDPK2_ORYSA (P53683) Calcium-dependent protein kinase, isoform 2 (EC 2.7.11.1)| (CDPK 2) Length = 533 Score = 109 bits (272), Expect = 6e-24 Identities = 62/170 (36%), Positives = 95/170 (55%), Gaps = 4/170 (2%) Frame = +3 Query: 63 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILR-LFMHP 239 Y +GK LG G FG + I +G + A K +++RK+ + +E ++REI+I++ L Sbjct: 85 YSLGKELGRGQFGVTYLCTEIASGKQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQQ 144 Query: 240 HIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNM 419 +I+ E ++++VVME GELFD I+ KG E+ A + +++ V CH Sbjct: 145 NIVEFRGAYEDKSNVHVVMELCAGGELFDRIIAKGHYSERAAATICRAVVNVVNICHFMG 204 Query: 420 VVHRDLKPENLLL---DNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 V+HRDLKPEN LL + N +K DFGLS + +G + GS Y A Sbjct: 205 VMHRDLKPENFLLATKEENAMLKATDFGLSVFIEEGKMYRDIVGSAYYVA 254
>PLK1_HUMAN (P53350) Serine/threonine-protein kinase PLK1 (EC 2.7.11.21)| (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13) Length = 603 Score = 109 bits (272), Expect = 6e-24 Identities = 65/174 (37%), Positives = 89/174 (51%), Gaps = 1/174 (0%) Frame = +3 Query: 42 DGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKIL 221 D + Y G+ LG G F K T A KI+ + + EK+ EI I Sbjct: 46 DPRSRRRYVRGRFLGKGGFAKCFEISDADTKEVFAGKIVPKSLLLKPHQREKMSMEISIH 105 Query: 222 RLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQ 401 R H H++ + E ++VV+E + L + + L E EAR + +QI+ G Q Sbjct: 106 RSLAHQHVVGFHGFFEDNDFVFVVLELCRRRSLLELHKRRKALTEPEARYYLRQIVLGCQ 165 Query: 402 YCHRNMVVHRDLKPENLLLDNNCDVKIADFGL-SNVMRDGHFLKTSCGSPNYAA 560 Y HRN V+HRDLK NL L+ + +VKI DFGL + V DG KT CG+PNY A Sbjct: 166 YLHRNRVIHRDLKLGNLFLNEDLEVKIGDFGLATKVEYDGERKKTLCGTPNYIA 219
>FUSED_DROME (P23647) Serine/threonine-protein kinase fused (EC 2.7.11.1)| Length = 805 Score = 108 bits (271), Expect = 8e-24 Identities = 61/170 (35%), Positives = 94/170 (55%), Gaps = 1/170 (0%) Frame = +3 Query: 54 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 233 + Y + +G GSFG V A VAIK++++R +++ ++RE I Sbjct: 1 MNRYAVSSLVGQGSFGCVYKATRKDDSKVVAIKVISKRGRATKELKN-LRRECDIQARLK 59 Query: 234 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 413 HPH+I + E E+ D++VV E+ +L Y+ G + E+ ARR ++S + Y H Sbjct: 60 HPHVIEMIESFESKTDLFVVTEFALM-DLHRYLSYNGAMGEEPARRVTGHLVSALYYLHS 118 Query: 414 NMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDG-HFLKTSCGSPNYAA 560 N ++HRDLKP+N+LLD N K+ DFGL+ M G H L + G+P Y A Sbjct: 119 NRILHRDLKPQNVLLDKNMHAKLCDFGLARNMTLGTHVLTSIKGTPLYMA 168
>TSSK6_HUMAN (Q9BXA6) Testis-specific serine/threonine-protein kinase 6 (EC| 2.7.11.1) (TSSK-6) (Small serine/threonine kinase) (Serine/threonine-protein kinase SSTK) Length = 273 Score = 108 bits (270), Expect = 1e-23 Identities = 66/169 (39%), Positives = 98/169 (57%), Gaps = 3/169 (1%) Frame = +3 Query: 63 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 242 Y++G+T+G GS+ KVK+A K VAIK+++RR+ + + + RE+ ILR HPH Sbjct: 12 YKLGRTIGEGSYSKVKVATSKKYKGTVAIKVVDRRRAPPDFVNKFLPRELSILRGVRHPH 71 Query: 243 IIRLYEVIEA-PADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNM 419 I+ ++E IE +Y+VME + +L + GR+ +AR F QI V+Y H + Sbjct: 72 IVHVFEFIEVCNGKLYIVMEAAAT-DLLQAVQRNGRIPGVQARDLFAQIAGAVRYLHDHH 130 Query: 420 VVHRDLKPENLLLD-NNCDVKIADFGLSNVMRDGHFLKTS-CGSPNYAA 560 +VHRDLK EN+LL + VK+ DFG L T+ CGS YA+ Sbjct: 131 LVHRDLKCENVLLSPDERRVKLTDFGFGRQAHGYPDLSTTYCGSAAYAS 179
>PLK2_CAEEL (Q9N2L7) Serine/threonine-protein kinase plk-2 (EC 2.7.11.21)| (Polo-like kinase 2) Length = 632 Score = 108 bits (270), Expect = 1e-23 Identities = 59/173 (34%), Positives = 88/173 (50%) Frame = +3 Query: 42 DGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKIL 221 DG Y GK LG G F + TG A K++ + + +K+ +E++I Sbjct: 29 DGERKTRYEKGKFLGKGGFAHCYELRNKSTGELFAGKVVPKALLIKQYQRDKMAQEVQIH 88 Query: 222 RLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQ 401 R H ++++LY E +++Y+ +E L + + + E EAR F QI+ GV Sbjct: 89 RNLQHRNVVKLYHFFEDKSNVYITLELCPRRSLMELHKRRKAVTEPEARYFTYQIVEGVL 148 Query: 402 YCHRNMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 Y H +VHRDLK NL L++ VKI DFGL+ + KT CG+PNY A Sbjct: 149 YLHNLKIVHRDLKLGNLFLNDELQVKIGDFGLATTCDNDERKKTLCGTPNYIA 201
>KPSH2_HUMAN (Q96QS6) Serine/threonine-protein kinase H2 (EC 2.7.11.1) (PSK-H2)| Length = 385 Score = 108 bits (270), Expect = 1e-23 Identities = 63/178 (35%), Positives = 94/178 (52%), Gaps = 5/178 (2%) Frame = +3 Query: 42 DGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKIL 221 D L Y I +G GSF +V E T AIK++ R+ + E E+ +L Sbjct: 56 DPRVLARYDIKALIGTGSFSRVVRVEQKTTKKPFAIKVMETREREG---REACVSELSVL 112 Query: 222 RLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQ 401 R H +I++L E+ E +Y+VME GELFD ++ +G E++A R Q + G++ Sbjct: 113 RRVSHRYIVQLMEIFETEDQVYMVMELATGGELFDRLIAQGSFTERDAVRILQMVADGIR 172 Query: 402 YCHRNMVVHRDLKPENLLL---DNNCDVKIADFGLS-NVMRDGHF-LKTSCGSPNYAA 560 Y H + HR+LKPENLL + I DFGL+ + + G + +KT CG+P Y A Sbjct: 173 YLHALQITHRNLKPENLLYYHPGEESKILITDFGLAYSGKKSGDWTMKTLCGTPEYIA 230
>KS6A5_CHICK (Q5F3L1) Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1)| Length = 789 Score = 108 bits (270), Expect = 1e-23 Identities = 69/182 (37%), Positives = 102/182 (56%), Gaps = 8/182 (4%) Frame = +3 Query: 39 KDGNPLKNYRIG---KTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKRE 209 KD ++Y + K LG GSF + H KT + A+KI+++R ME +RE Sbjct: 405 KDSPFFQHYELDLKEKPLGEGSFSICRKCLHKKTSQEYAVKIISKR------MEANTQRE 458 Query: 210 IKILRLFM-HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQI 386 I L+L HP++++L+EV ++VME +K GEL + I +K E EA +++ Sbjct: 459 ITALKLCEGHPNVVKLHEVYHDQLHTFLVMELLKGGELLERIQKKQHFSETEASHIMRRL 518 Query: 387 ISGVQYCHRNMVVHRDLKPENLLL---DNNCDVKIADFGLSNVM-RDGHFLKTSCGSPNY 554 +S V + H VVHRDLKPENLL +N ++KI DFG + + D LKT C + +Y Sbjct: 519 VSAVSHMHDVGVVHRDLKPENLLFTDETDNSEIKIIDFGFARLKPPDNQPLKTPCFTLHY 578 Query: 555 AA 560 AA Sbjct: 579 AA 580 Score = 87.4 bits (215), Expect = 2e-17 Identities = 46/176 (26%), Positives = 97/176 (55%), Gaps = 7/176 (3%) Frame = +3 Query: 54 LKNYRIGKTLGIGSFGKVKIAEHIK---TGHKVAIKILNRRKI-KNMDMEEKVKREIKIL 221 ++N+ + K LG G++GKV + + G A+K+L + I + E + E ++L Sbjct: 36 IENFELLKVLGTGAYGKVFLVRKVSGHDAGKLYAMKVLKKATIVQKAKTTEHTRTERQVL 95 Query: 222 R-LFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGV 398 + P ++ L+ + ++++++Y+ GELF ++ ++ R E E + + +I+ + Sbjct: 96 EHIRQSPFLVTLHYAFQTDTKLHLILDYINGGELFTHLSQRERFSENEVQIYIGEIVLAL 155 Query: 399 QYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLSN--VMRDGHFLKTSCGSPNYAA 560 ++ H+ +++RD+K EN+LLD++ V + DFGLS + + + CG+ Y A Sbjct: 156 EHLHKLGIIYRDIKLENILLDSDGHVVLTDFGLSKEFLTDENERAYSFCGTIEYMA 211
>CRK_DAUCA (P53681) CDPK-related protein kinase (EC 2.7.11.1) (PK421)| Length = 602 Score = 108 bits (269), Expect = 1e-23 Identities = 64/174 (36%), Positives = 98/174 (56%), Gaps = 8/174 (4%) Frame = +3 Query: 63 YRIGKTLGIGSFG---KVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILR-LF 230 + +G+ +G G FG + K + G VA+K++ + K+ E V+RE+KILR L Sbjct: 148 FEVGEEVGRGHFGYTCRAKFKKGEFKGQDVAVKVIPKAKMTTAIAIEDVRREVKILRALT 207 Query: 231 MHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKG-RLQEQEARRFFQQIISGVQYC 407 H ++++ Y+ E ++YVVME + GEL D I+ +G + E +A+ QI++ V +C Sbjct: 208 GHNNLVQFYDAFEDHTNVYVVMELCEGGELLDRILSRGGKYTEDDAKAVMIQILNVVAFC 267 Query: 408 HRNMVVHRDLKPENLLL---DNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 H VVHRDLKPEN L D + +K DFGLS+ ++ L GS Y A Sbjct: 268 HLQGVVHRDLKPENFLFKSKDEDSQLKAIDFGLSDYVKPDERLNDIVGSAYYVA 321
>PLK2_MOUSE (P53351) Serine/threonine-protein kinase PLK2 (EC 2.7.11.21)| (Polo-like kinase 1) (PLK-2) (Serine/threonine-protein kinase SNK) (Serum-inducible kinase) Length = 682 Score = 107 bits (268), Expect = 2e-23 Identities = 54/167 (32%), Positives = 88/167 (52%), Gaps = 1/167 (0%) Frame = +3 Query: 57 KNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMH 236 K Y GK LG G F K + A KI+ ++ EK+ +EI++ RL H Sbjct: 77 KRYCRGKVLGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVAKPHQREKIDKEIELHRLLHH 136 Query: 237 PHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRN 416 H+++ Y E +IY+++EY + + + L E E R + +QI+SG++Y H Sbjct: 137 KHVVQFYHYFEDKENIYILLEYCSRRSMAHILKARKVLTEPEVRYYLRQIVSGLKYLHEQ 196 Query: 417 MVVHRDLKPENLLLDNNCDVKIADFGLSNVMRD-GHFLKTSCGSPNY 554 ++HRDLK N ++ ++K+ DFGL+ + H +T CG+PNY Sbjct: 197 EILHRDLKLGNFFINEAMELKVGDFGLAARLEPLEHRRRTICGTPNY 243
>ST17A_HUMAN (Q9UEE5) Serine/threonine-protein kinase 17A (EC 2.7.11.1) (DAP| kinase-related apoptosis-inducing protein kinase 1) Length = 414 Score = 107 bits (268), Expect = 2e-23 Identities = 60/169 (35%), Positives = 97/169 (57%), Gaps = 6/169 (3%) Frame = +3 Query: 72 GKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM-HPHII 248 G+ LG G F V+ +G + A K + +R+ K D ++ EI +L L +P +I Sbjct: 64 GRELGRGKFAVVRKCIKKDSGKEFAAKFMRKRR-KGQDCRMEIIHEIAVLELAQDNPWVI 122 Query: 249 RLYEVIEAPADIYVVMEYVKSGELFDYIV--EKGRLQEQEARRFFQQIISGVQYCHRNMV 422 L+EV E +++ +V+EY GE+FD V + +E++ +R +QI+ GV + H V Sbjct: 123 NLHEVYETASEMILVLEYAAGGEIFDQCVADREEAFKEKDVQRLMRQILEGVHFLHTRDV 182 Query: 423 VHRDLKPENLLLDNNC---DVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 VH DLKP+N+LL + D+KI DFGLS ++++ L+ G+P Y A Sbjct: 183 VHLDLKPQNILLTSESPLGDIKIVDFGLSRILKNSEELREIMGTPEYVA 231
>KCC2G_HUMAN (Q13555) Calcium/calmodulin-dependent protein kinase type II gamma| chain (EC 2.7.11.17) (CaM-kinase II gamma chain) (CaM kinase II gamma subunit) (CaMK-II gamma subunit) Length = 558 Score = 107 bits (267), Expect = 2e-23 Identities = 59/150 (39%), Positives = 91/150 (60%), Gaps = 3/150 (2%) Frame = +3 Query: 60 NYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHP 239 +Y++ + LG G+F V+ + + A KI+N +K+ D +K++RE +I RL HP Sbjct: 13 DYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARD-HQKLEREARICRLLKHP 71 Query: 240 HIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNM 419 +I+RL++ I Y+V + V GELF+ IV + E +A QI+ V + H++ Sbjct: 72 NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHD 131 Query: 420 VVHRDLKPENLLLDNNCD---VKIADFGLS 500 +VHRDLKPENLLL + C VK+ADFGL+ Sbjct: 132 IVHRDLKPENLLLASKCKGAAVKLADFGLA 161
>KCC2G_RAT (P11730) Calcium/calmodulin-dependent protein kinase type II gamma| chain (EC 2.7.11.17) (CaM-kinase II gamma chain) (CaM kinase II gamma subunit) (CaMK-II gamma subunit) Length = 527 Score = 107 bits (267), Expect = 2e-23 Identities = 59/150 (39%), Positives = 91/150 (60%), Gaps = 3/150 (2%) Frame = +3 Query: 60 NYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHP 239 +Y++ + LG G+F V+ + + A KI+N +K+ D +K++RE +I RL HP Sbjct: 13 DYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARD-HQKLEREARICRLLKHP 71 Query: 240 HIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNM 419 +I+RL++ I Y+V + V GELF+ IV + E +A QI+ V + H++ Sbjct: 72 NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHD 131 Query: 420 VVHRDLKPENLLLDNNCD---VKIADFGLS 500 +VHRDLKPENLLL + C VK+ADFGL+ Sbjct: 132 IVHRDLKPENLLLASKCKGAAVKLADFGLA 161
>PKN2_BACSU (O34507) Probable serine/threonine-protein kinase yloP (EC| 2.7.11.1) Length = 648 Score = 107 bits (267), Expect = 2e-23 Identities = 56/166 (33%), Positives = 93/166 (56%), Gaps = 2/166 (1%) Frame = +3 Query: 63 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 242 Y+I + +G G V +AE I +VAIKIL + + + +RE + HP+ Sbjct: 11 YQILRVIGGGGMANVYLAEDIILDREVAIKILRFDYANDNEFIRRFRREAQSASSLDHPN 70 Query: 243 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 422 I+ +Y++ E Y+VMEYV+ L +YI G L +EA +QI+S + + H+N + Sbjct: 71 IVSIYDLGEEDDIYYIVMEYVEGMTLKEYITANGPLHPKEALNIMEQIVSAIAHAHQNQI 130 Query: 423 VHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTS--CGSPNY 554 VHRD+KP N+L+D+ ++K+ DFG++ + T+ GS +Y Sbjct: 131 VHRDIKPHNILIDHMGNIKVTDFGIATALSSTTITHTNSVLGSVHY 176
>KCC2G_MOUSE (Q923T9) Calcium/calmodulin-dependent protein kinase type II gamma| chain (EC 2.7.11.17) (CaM-kinase II gamma chain) (CaM kinase II gamma subunit) (CaMK-II gamma subunit) Length = 529 Score = 107 bits (267), Expect = 2e-23 Identities = 59/150 (39%), Positives = 91/150 (60%), Gaps = 3/150 (2%) Frame = +3 Query: 60 NYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHP 239 +Y++ + LG G+F V+ + + A KI+N +K+ D +K++RE +I RL HP Sbjct: 13 DYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARD-HQKLEREARICRLLKHP 71 Query: 240 HIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNM 419 +I+RL++ I Y+V + V GELF+ IV + E +A QI+ V + H++ Sbjct: 72 NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHD 131 Query: 420 VVHRDLKPENLLLDNNCD---VKIADFGLS 500 +VHRDLKPENLLL + C VK+ADFGL+ Sbjct: 132 IVHRDLKPENLLLASKCKGAAVKLADFGLA 161
>ULK1_MOUSE (O70405) Serine/threonine-protein kinase ULK1 (EC 2.7.11.1)| (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1) Length = 1051 Score = 107 bits (266), Expect = 3e-23 Identities = 62/170 (36%), Positives = 90/170 (52%), Gaps = 10/170 (5%) Frame = +3 Query: 81 LGIGSFGKVKIAEHI-KTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPHIIRLY 257 +G G+F V H K +VA+K +N++ + + + +EIKIL+ H +I+ LY Sbjct: 22 IGHGAFAVVFKGRHREKHDLEVAVKCINKKNLAKS--QTLLGKEIKILKELKHENIVALY 79 Query: 258 EVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMVVHRDL 437 + E +Y+VMEY G+L DY+ L E R F QQI ++ H ++HRDL Sbjct: 80 DFQEMANSVYLVMEYCNGGDLADYLHTMRTLSEDTVRLFLQQIAGAMRLLHSKGIIHRDL 139 Query: 438 KPENLLLDN---------NCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 KP+N+LL N N VKIADFG + ++ T CGSP Y A Sbjct: 140 KPQNILLSNPGGRRANPSNIRVKIADFGFARYLQSNMMAATLCGSPMYMA 189
>PLK2_RAT (Q9R012) Serine/threonine-protein kinase PLK2 (EC 2.7.11.21)| (Polo-like kinase 1) (PLK-2) (Serine/threonine-protein kinase SNK) (Serum-inducible kinase) Length = 682 Score = 107 bits (266), Expect = 3e-23 Identities = 53/167 (31%), Positives = 88/167 (52%), Gaps = 1/167 (0%) Frame = +3 Query: 57 KNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMH 236 K Y GK LG G F K + A KI+ ++ EK+ +EI++ R+ H Sbjct: 77 KRYCRGKVLGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVAKPHQREKIDKEIELHRILHH 136 Query: 237 PHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRN 416 H+++ Y E +IY+++EY + + + L E E R + +QI+SG++Y H Sbjct: 137 KHVVQFYHYFEDKENIYILLEYCSRRSMAHILKARKVLTEPEVRYYLRQIVSGLKYLHEQ 196 Query: 417 MVVHRDLKPENLLLDNNCDVKIADFGLSNVMRD-GHFLKTSCGSPNY 554 ++HRDLK N ++ ++K+ DFGL+ + H +T CG+PNY Sbjct: 197 EILHRDLKLGNFFINEAMELKVGDFGLAARLEPLEHRRRTICGTPNY 243
>PLK1_XENLA (P70032) Serine/threonine-protein kinase PLK1 (EC 2.7.11.21)| (Polo-like kinase 1) (PLK-1) (Plx1) Length = 598 Score = 107 bits (266), Expect = 3e-23 Identities = 63/174 (36%), Positives = 91/174 (52%), Gaps = 1/174 (0%) Frame = +3 Query: 42 DGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKIL 221 D + Y G+ LG G F K +++ A KI+ + + ++K+ EI I Sbjct: 37 DPRTRRRYLRGRFLGKGGFAKCYEITDLESREVFAGKIVPKTMLLKPHQKDKMTMEIAIQ 96 Query: 222 RLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQ 401 R H H++ + E +YVV+E + L + + + E EAR + +Q ISG Q Sbjct: 97 RSLDHRHVVGFHGFFEDNDFVYVVLELCRRRSLLELHKRRKAVTEPEARYYLKQTISGCQ 156 Query: 402 YCHRNMVVHRDLKPENLLLDNNCDVKIADFGL-SNVMRDGHFLKTSCGSPNYAA 560 Y H N V+HRDLK NL L++ +VKI DFGL + V DG KT CG+PNY A Sbjct: 157 YLHSNRVIHRDLKLGNLFLNDEMEVKIGDFGLATKVEYDGERKKTLCGTPNYIA 210
>PLK2_HUMAN (Q9NYY3) Serine/threonine-protein kinase PLK2 (EC 2.7.11.21)| (Polo-like kinase 1) (PLK-2) (Serine/threonine-protein kinase SNK) (Serum-inducible kinase) Length = 685 Score = 107 bits (266), Expect = 3e-23 Identities = 53/167 (31%), Positives = 88/167 (52%), Gaps = 1/167 (0%) Frame = +3 Query: 57 KNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMH 236 K Y GK LG G F K + A KI+ ++ EK+ +EI++ R+ H Sbjct: 80 KRYCRGKVLGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVAKPHQREKIDKEIELHRILHH 139 Query: 237 PHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRN 416 H+++ Y E +IY+++EY + + + L E E R + +QI+SG++Y H Sbjct: 140 KHVVQFYHYFEDKENIYILLEYCSRRSMAHILKARKVLTEPEVRYYLRQIVSGLKYLHEQ 199 Query: 417 MVVHRDLKPENLLLDNNCDVKIADFGLSNVMRD-GHFLKTSCGSPNY 554 ++HRDLK N ++ ++K+ DFGL+ + H +T CG+PNY Sbjct: 200 EILHRDLKLGNFFINEAMELKVGDFGLAARLEPLEHRRRTICGTPNY 246
>PIM1_BRARE (Q9YHZ5) Serine/threonine-protein kinase Pim-1 (EC 2.7.11.1)| Length = 310 Score = 106 bits (265), Expect = 4e-23 Identities = 63/171 (36%), Positives = 91/171 (53%), Gaps = 15/171 (8%) Frame = +3 Query: 57 KNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDME----EKVKREIKILR 224 K Y +G LG G FG V I G KVAIK ++R +I+ V EI +L+ Sbjct: 28 KQYTMGNLLGSGGFGSVYSGHRISDGQKVAIKQISRDRIQQWSKMPGEVNPVPNEIALLQ 87 Query: 225 LFM--------HPHIIRLYEVIEAPADIYVVM--EYVKSGELFDYIVEKGRLQEQEARRF 374 H IIR+ + E P Y+++ + +LFD+I E+GRL E ARRF Sbjct: 88 SLGGGSGSVPGHRGIIRMLDWFEIPGQEYLIVFEKPQHCQDLFDFITERGRLDESLARRF 147 Query: 375 FQQIISGVQYCHRNMVVHRDLKPENLLLDNNC-DVKIADFGLSNVMRDGHF 524 +Q+I VQ+CH +VHRD+K EN+L+D D+K+ DFG ++D + Sbjct: 148 LKQVIEAVQFCHSKGIVHRDIKDENILVDTRTGDIKVIDFGSGATLKDSMY 198
>KPC4_DROME (P83099) Putative protein kinase C, delta type homolog (EC| 2.7.11.13) Length = 643 Score = 106 bits (265), Expect = 4e-23 Identities = 65/177 (36%), Positives = 101/177 (57%), Gaps = 9/177 (5%) Frame = +3 Query: 57 KNYRIGK-----TLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKIL 221 KNY + LG GSFGKV +AE T + AIK L + + D + E K+L Sbjct: 308 KNYSVDDFHFLAVLGKGSFGKVLLAELRDTTYYYAIKCLKKDVVLEDDDVDSTLIERKVL 367 Query: 222 RL-FMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGV 398 L HP++ L+ + + ++ VMEY+ G+L +I E GR E+ AR + +IISG+ Sbjct: 368 ALGTKHPYLCHLFCTFQTESHLFFVMEYLNGGDLMFHIQESGRFSEERARFYGAEIISGL 427 Query: 399 QYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTS---CGSPNYAA 560 ++ H+ +++RDLK +N+LLD V+IADFG+ + + KT+ CG+P+Y A Sbjct: 428 KFLHKKGIIYRDLKLDNVLLDYEGHVRIADFGMCKLQI--YLDKTADSFCGTPDYMA 482
>PKD1_DICDI (P34100) Developmentally-regulated protein kinase 1 (EC 2.7.11.1)| (Fragment) Length = 416 Score = 106 bits (265), Expect = 4e-23 Identities = 53/169 (31%), Positives = 85/169 (50%) Frame = +3 Query: 54 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 233 + ++ +LG GSFG K+ H +G K L R I + +E V EI I+ Sbjct: 33 ISDFNFYGSLGSGSFGTAKLCRHRGSGLFFCSKTLRRETIVHEKHKEHVNNEINIMLNIS 92 Query: 234 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 413 HP+I++ Y P I+ +MEY +LF ++ EQ + +I+ ++Y H Sbjct: 93 HPYIVKTYSTFNTPTKIHFIMEYAGKKDLFHHLRANKCFTEQTTKLIVAEIVLAIEYLHA 152 Query: 414 NMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFLKTSCGSPNYAA 560 +++RDLKPEN+L+D +K+ DFG S G + CG+ +Y A Sbjct: 153 ENIIYRDLKPENILIDEKGHIKLTDFGFSKKTVGGKNTSSVCGTFDYMA 201
>AKT2A_XENLA (Q7ZX15) RAC-beta serine/threonine-protein kinase-A (EC 2.7.11.1)| (RAC-PK-beta-A) (Protein kinase Akt-2-A) (Protein kinase B, beta-A) (PKB beta-A) Length = 486 Score = 106 bits (265), Expect = 4e-23 Identities = 64/184 (34%), Positives = 96/184 (52%), Gaps = 4/184 (2%) Frame = +3 Query: 21 KMEAGGKDGNP---LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDME 191 +M+ G+P + ++ K LG G+FGKV + TG A+KIL + I D Sbjct: 140 QMDVAMSKGHPKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEV 199 Query: 192 EKVKREIKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARR 371 E ++L+ HP + L + + VMEY GELF ++ + E AR Sbjct: 200 AHTLTESRVLQNTKHPFLTALKYAFQTSDRLCFVMEYANGGELFFHLSRERVFTEDRARF 259 Query: 372 FFQQIISGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGL-SNVMRDGHFLKTSCGSP 548 + +I+S ++Y H VV+RD+K ENL+LD + VKI DFGL + DG ++T CG+P Sbjct: 260 YGAEIVSALEYLHSRNVVYRDIKLENLMLDKDGHVKITDFGLCKEGITDGATMRTFCGTP 319 Query: 549 NYAA 560 Y A Sbjct: 320 EYLA 323
>KPCL_RAT (Q64617) Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta)| (PKC-L) Length = 683 Score = 106 bits (265), Expect = 4e-23 Identities = 65/188 (34%), Positives = 101/188 (53%), Gaps = 12/188 (6%) Frame = +3 Query: 33 GGKDGNPL----------KNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNM 182 G K+GN + N+ + LG GSFGKV +A +TG A+K+L + I Sbjct: 335 GSKEGNGIGVNSSSRFGIDNFEFIRVLGKGSFGKVMLARIKETGELYAVKVLKKDVILQD 394 Query: 183 DMEEKVKREIKILRLFM-HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQ 359 D E E +IL L HP + +L+ + P ++ VME+V G+L +I + R E Sbjct: 395 DDVECTMTEKRILSLARNHPFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEA 454 Query: 360 EARRFFQQIISGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGL-SNVMRDGHFLKTS 536 AR + +IIS + + H +++RDLK +N+LLD+ K+ADFG+ + +G T Sbjct: 455 RARFYAAEIISALMFLHEKGIIYRDLKLDNVLLDHEGHCKLADFGMCKEGICNGVTTATF 514 Query: 537 CGSPNYAA 560 CG+P+Y A Sbjct: 515 CGTPDYIA 522
>KPCL_MOUSE (P23298) Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta)| (PKC-L) Length = 683 Score = 106 bits (265), Expect = 4e-23 Identities = 65/188 (34%), Positives = 101/188 (53%), Gaps = 12/188 (6%) Frame = +3 Query: 33 GGKDGNPL----------KNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNM 182 G K+GN + N+ + LG GSFGKV +A +TG A+K+L + I Sbjct: 335 GSKEGNGIGVNSSSRFGIDNFEFIRVLGKGSFGKVMLARIKETGELYAVKVLKKDVILQD 394 Query: 183 DMEEKVKREIKILRLFM-HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQ 359 D E E +IL L HP + +L+ + P ++ VME+V G+L +I + R E Sbjct: 395 DDVECTMTEKRILSLARNHPFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEA 454 Query: 360 EARRFFQQIISGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGL-SNVMRDGHFLKTS 536 AR + +IIS + + H +++RDLK +N+LLD+ K+ADFG+ + +G T Sbjct: 455 RARFYAAEIISALMFLHEKGIIYRDLKLDNVLLDHEGHCKLADFGMCKEGICNGVTTATF 514 Query: 537 CGSPNYAA 560 CG+P+Y A Sbjct: 515 CGTPDYIA 522
>KS6A5_HUMAN (O75582) Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1) (Nuclear| mitogen-and stress-activated protein kinase 1) (90 kDa ribosomal protein S6 kinase 5) (RSK-like protein kinase) (RSKL) Length = 802 Score = 106 bits (264), Expect = 5e-23 Identities = 65/167 (38%), Positives = 96/167 (57%), Gaps = 5/167 (2%) Frame = +3 Query: 75 KTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM-HPHIIR 251 K LG GSF + H K+ A+KI+++R ME ++EI L+L HP+I++ Sbjct: 430 KPLGEGSFSICRKCVHKKSNQAFAVKIISKR------MEANTQKEITALKLCEGHPNIVK 483 Query: 252 LYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMVVHR 431 L+EV ++VME + GELF+ I +K E EA ++++S V + H VVHR Sbjct: 484 LHEVFHDQLHTFLVMELLNGGELFERIKKKKHFSETEASYIMRKLVSAVSHMHDVGVVHR 543 Query: 432 DLKPENLLL---DNNCDVKIADFGLSNVM-RDGHFLKTSCGSPNYAA 560 DLKPENLL ++N ++KI DFG + + D LKT C + +YAA Sbjct: 544 DLKPENLLFTDENDNLEIKIIDFGFARLKPPDNQPLKTPCFTLHYAA 590 Score = 91.3 bits (225), Expect = 2e-18 Identities = 50/176 (28%), Positives = 98/176 (55%), Gaps = 7/176 (3%) Frame = +3 Query: 54 LKNYRIGKTLGIGSFGKVKIAEHIK---TGHKVAIKILNRRKI-KNMDMEEKVKREIKIL 221 ++N+ + K LG G++GKV + I TG A+K+L + I + E + E ++L Sbjct: 46 IENFELLKVLGTGAYGKVFLVRKISGHDTGKLYAMKVLKKATIVQKAKTTEHTRTERQVL 105 Query: 222 R-LFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGV 398 + P ++ L+ + ++++++Y+ GELF ++ ++ R E E + + +I+ + Sbjct: 106 EHIRQSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLAL 165 Query: 399 QYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLSN--VMRDGHFLKTSCGSPNYAA 560 ++ H+ +++RD+K EN+LLD+N V + DFGLS V + + CG+ Y A Sbjct: 166 EHLHKLGIIYRDIKLENILLDSNGHVVLTDFGLSKEFVADETERAYSFCGTIEYMA 221
>KSG1_SCHPO (Q12701) Serine/threonine-protein kinase ksg1 (EC 2.7.11.1)| Length = 592 Score = 106 bits (264), Expect = 5e-23 Identities = 56/157 (35%), Positives = 88/157 (56%), Gaps = 1/157 (0%) Frame = +3 Query: 54 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 233 + +++ G+ LG GS+ V A T + AIK+L++R I E+ V E + L + Sbjct: 96 VSDFKFGEILGEGSYSTVLTATENSTKREYAIKVLDKRHIIKEKKEKYVNIEKEALCILS 155 Query: 234 -HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCH 410 HP I+L+ + ++Y V+ ++GEL DYI + GR E A+ + I+ + Y H Sbjct: 156 KHPGFIKLFYTFQDAHNLYFVLSLARNGELLDYINKLGRFNEICAQYYAALIVDSIDYMH 215 Query: 411 RNMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGH 521 V+HRDLKPEN+LLD+N KI DFG + ++ H Sbjct: 216 GRGVIHRDLKPENILLDDNMRTKITDFGSAKILNSSH 252
>AKT2_RAT (P47197) RAC-beta serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta) Length = 481 Score = 106 bits (264), Expect = 5e-23 Identities = 61/163 (37%), Positives = 88/163 (53%), Gaps = 1/163 (0%) Frame = +3 Query: 75 KTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPHIIRL 254 K LG G+FGKV + TG A+KIL + I D E ++L+ HP + L Sbjct: 156 KLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQNTRHPFLTAL 215 Query: 255 YEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMVVHRD 434 + + VMEY G+LF ++ + E AR + +I+S ++Y H VV+RD Sbjct: 216 KYAFQTHDRLCFVMEYANGGDLFFHLSRERVFTEDRARFYGAEIVSALEYLHSTDVVYRD 275 Query: 435 LKPENLLLDNNCDVKIADFGLSNV-MRDGHFLKTSCGSPNYAA 560 +K ENL+LD + +KI DFGLS + DG +KT CG+P Y A Sbjct: 276 IKLENLMLDKDGHIKITDFGLSKEGISDGATMKTFCGTPEYLA 318 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 87,838,563 Number of Sequences: 219361 Number of extensions: 1904132 Number of successful extensions: 9614 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 7550 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 7907 length of database: 80,573,946 effective HSP length: 106 effective length of database: 57,321,680 effective search space used: 4585734400 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
