>VILI3_ARATH (O81645) Villin-3|
          Length = 966

 Score =  241 bits (615), Expect = 2e-63
 Identities = 124/228 (54%), Positives = 153/228 (67%), Gaps = 2/228 (0%)
 Frame = +1

Query: 22   ARXGTXXSAFWFALDGKQSYTSKPIMQDTIVRDPHLYAFSIRKGRLEVTEIFNFCQDDLL 201
            A+ GT  S+FWFAL GKQ++TSK +  +T VRDPHL++FS  +G+ +V EI NF QDDLL
Sbjct: 591  AKEGTESSSFWFALGGKQNFTSKKVSSET-VRDPHLFSFSFNRGKFQVEEIHNFDQDDLL 649

Query: 202  TEDLMILDTHGEVFIWIGQCVEPKEKQKAFDIGQKYIEHAMSIEDLSPYVPLYKVSEGNE 381
            TE++ +LDTH EVF+W+GQCV+PKEKQ AF+IGQ+YI  A S+E LSP VPLYK++EGNE
Sbjct: 650  TEEMHLLDTHAEVFVWVGQCVDPKEKQTAFEIGQRYINLAGSLEGLSPKVPLYKITEGNE 709

Query: 382  PCFFKTYFSWDSTKSVIHGNSFQKKLSLLFGLRSEVIWGASRSSGNGGPTQRXXXXXXXX 561
            PCFF TYFSWDSTK+ + GNS+QKK +LL G    V      SSGN GP QR        
Sbjct: 710  PCFFTTYFSWDSTKATVQGNSYQKKAALLLGTHHVV--EDQSSSGNQGPRQRAAALAALT 767

Query: 562  XXFNPSSQQKQVNDSRPPSSGD--GPTQRXXXXXXXXXXXFNPSPQQK 699
              FN SS  +  + SR  S+G   GP QR           FN SP  K
Sbjct: 768  SAFN-SSSGRTSSPSRDRSNGSQGGPRQR-AEALAALTSAFNSSPSSK 813



 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 39/159 (24%), Positives = 72/159 (45%), Gaps = 4/159 (2%)
 Frame = +1

Query: 49  FWFALDGKQSYTSKPIMQDTIVRD---PHLYAFSIRKGRLEVTEIFNFCQDDLLTEDLMI 219
           FW    G      K   +D I+ +   P LY  SI  G++E  +  +  +  L      +
Sbjct: 227 FWVLFGGFAPIARKVASEDEIIPETTPPKLY--SIADGQVESID-GDLSKSMLENNKCYL 283

Query: 220 LDTHGEVFIWIGQCVEPKEKQKAFDIGQKYIEHAMSIEDLSPYVPLYKVSEGNEPCFFKT 399
           LD   E+FIW+G+  + +E++ A    + ++    + E+      + +V +G EP  FK+
Sbjct: 284 LDCGSEIFIWVGRVTQVEERKTAIQAAEDFV----ASENRPKATRITRVIQGYEPHSFKS 339

Query: 400 YF-SWDSTKSVIHGNSFQKKLSLLFGLRSEVIWGASRSS 513
            F SW S  +       + K++ L   +   + G S+S+
Sbjct: 340 NFDSWPSGSATPANEEGRGKVAALLKQQGVGLKGLSKST 378

>VILI2_ARATH (O81644) Villin-2|
          Length = 976

 Score =  238 bits (606), Expect = 2e-62
 Identities = 120/234 (51%), Positives = 148/234 (63%), Gaps = 1/234 (0%)
 Frame = +1

Query: 22   ARXGTXXSAFWFALDGKQSYTSKPIMQDTIVRDPHLYAFSIRKGRLEVTEIFNFCQDDLL 201
            A+ GT  S FWFAL GKQ++TSK    +TI RDPHL++F+  +G+ +V EI+NF QDDLL
Sbjct: 589  AKEGTESSTFWFALGGKQNFTSKKASSETI-RDPHLFSFAFNRGKFQVEEIYNFAQDDLL 647

Query: 202  TEDLMILDTHGEVFIWIGQCVEPKEKQKAFDIGQKYIEHAMSIEDLSPYVPLYKVSEGNE 381
            TED+  LDTH EVF+W+GQCVEPKEKQ  F+IGQKYI+ A S+E L P VP+YK++EGNE
Sbjct: 648  TEDIYFLDTHAEVFVWVGQCVEPKEKQTVFEIGQKYIDLAGSLEGLHPKVPIYKINEGNE 707

Query: 382  PCFFKTYFSWDSTKSVIHGNSFQKKLSLLFGLRSEVIWGASRSSGNGGPTQRXXXXXXXX 561
            PCFF TYFSWD+TK+++ GNSFQKK SLLFG    V      + GN G  QR        
Sbjct: 708  PCFFTTYFSWDATKAIVQGNSFQKKASLLFGTHHVV--EDKSNGGNQGLRQRAEALAALN 765

Query: 562  XXFNPSSQQKQV-NDSRPPSSGDGPTQRXXXXXXXXXXXFNPSPQQKQVNDSRP 720
              FN SS +    +  R   S DGP QR            + S   K     RP
Sbjct: 766  SAFNSSSNRPAYSSQDRLNESHDGPRQRAEALAALSSAFNSSSSSTKSPPPPRP 819



 Score = 38.5 bits (88), Expect = 0.021
 Identities = 37/160 (23%), Positives = 70/160 (43%), Gaps = 4/160 (2%)
 Frame = +1

Query: 46  AFWFALDGKQSYTSKPIMQDTIVRD---PHLYAFSIRKGRLEVTEIFNFCQDDLLTEDLM 216
           AFW    G      K    D IV +   P LY   I  G++E  +  +  +  L      
Sbjct: 224 AFWVLFGGFAPIGRKVANDDDIVPESTPPKLYC--ITDGKMEPID-GDLSKSMLENTKCY 280

Query: 217 ILDTHGEVFIWIGQCVEPKEKQKAFDIGQKYIEHAMSIEDLSPYVPLYKVSEGNEPCFFK 396
           +LD   E++IW+G+  +  E++ A    +++    ++ E+      + +V +G E   FK
Sbjct: 281 LLDCGAEIYIWVGRVTQVDERKAASQSAEEF----LASENRPKATHVTRVIQGYESHSFK 336

Query: 397 TYF-SWDSTKSVIHGNSFQKKLSLLFGLRSEVIWGASRSS 513
           + F SW S  +       + K++ L   +   + G ++S+
Sbjct: 337 SNFDSWPSGSATPGNEEGRGKVAALLKQQGVGLKGIAKSA 376

>VILI4_ARATH (O65570) Villin-4|
          Length = 974

 Score =  154 bits (390), Expect = 2e-37
 Identities = 73/149 (48%), Positives = 102/149 (68%), Gaps = 1/149 (0%)
 Frame = +1

Query: 25   RXGTXXSAFWFALDGKQSYTSKPIMQDTIVRDPHLYAFSIRKGRLEVTEIFNFCQDDLLT 204
            + G+    FW  L GK  Y+S+ + ++   RDPHL++ +  K  L+VTEI+NF QDDL+T
Sbjct: 591  KEGSESEQFWELLGGKAEYSSQKLTKEP-ERDPHLFSCTFTKEVLKVTEIYNFTQDDLMT 649

Query: 205  EDLMILDTHGEVFIWIGQCVEPKEKQKAFDIGQKYIEHAMSIEDLSPYVPLYKVSEGNEP 384
            ED+ I+D H E+F+W+GQ V PK K  A  IG+K+IE    +E LSP  P+Y + EG EP
Sbjct: 650  EDIFIIDCHSEIFVWVGQEVVPKNKLLALTIGEKFIEKDSLLEKLSPEAPIYVIMEGGEP 709

Query: 385  CFFKTYF-SWDSTKSVIHGNSFQKKLSLL 468
             FF  +F SWDS+KS +HGNSFQ+KL ++
Sbjct: 710  SFFTRFFTSWDSSKSAMHGNSFQRKLKIV 738



 Score = 32.0 bits (71), Expect = 2.0
 Identities = 24/93 (25%), Positives = 42/93 (45%), Gaps = 1/93 (1%)
 Frame = +1

Query: 136 FSIRKGRLEVTEIFNFCQDDLLTEDLMILDTHGEVFIWIGQCVEPKEKQKAFDIGQKYIE 315
           F + KG+    E     ++ L T    ILD   EVF+W+G+     +++ A    ++ I 
Sbjct: 257 FCVEKGQANPVEGDTLKREMLDTNKCYILDCGIEVFVWMGRTTSLDDRKIASKAAEEMIR 316

Query: 316 HAMSIEDLSPYVPLYKVSEGNEPCFFKTYF-SW 411
            +       P   + ++ EG E   F++ F SW
Sbjct: 317 SSE-----RPKSQMIRIIEGFETVPFRSKFESW 344

>VILI1_ARATH (O81643) Villin-1|
          Length = 910

 Score =  127 bits (319), Expect = 3e-29
 Identities = 67/165 (40%), Positives = 96/165 (58%)
 Frame = +1

Query: 25   RXGTXXSAFWFALDGKQSYTSKPIMQDTIVRDPHLYAFSIRKGRLEVTEIFNFCQDDLLT 204
            R G     FW  L GK  Y  +  M+  I  +PHL+  S     L+V EI+NF QDDL T
Sbjct: 589  REGNETDTFWNLLGGKSEYPKEKEMRKQI-EEPHLFTCSCSSDVLKVKEIYNFVQDDLTT 647

Query: 205  EDLMILDTHGEVFIWIGQCVEPKEKQKAFDIGQKYIEHAMSIEDLSPYVPLYKVSEGNEP 384
            ED+ +LD   EV++WIG     K K++A  +G K++E  +  E L+   P+Y V+EG+EP
Sbjct: 648  EDVFLLDCQSEVYVWIGSNSNIKSKEEALTLGLKFLEMDILEEGLTMRTPVYVVTEGHEP 707

Query: 385  CFFKTYFSWDSTKSVIHGNSFQKKLSLLFGLRSEVIWGASRSSGN 519
             FF  +F W   K+ +HGNSF++KL+ L G ++       RSSG+
Sbjct: 708  PFFTRFFEWVPEKANMHGNSFERKLASLKGKKT----STKRSSGS 748



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 30/110 (27%), Positives = 55/110 (50%), Gaps = 2/110 (1%)
 Frame = +1

Query: 148 KGRLEVTEIFNFCQDDLLTEDLMILDTHGEVFIWIGQCVEPKEKQKAFDIGQKYIEHAMS 327
           KG L  T   +  +D L      +LD H EVF+W+G+     E++ +    ++++     
Sbjct: 261 KGNLHPTGTSSLDKDMLEKNKCYMLDCHSEVFVWMGRNTSLTERKTSISSSEEFLRK--- 317

Query: 328 IEDLSPYVPLYKVSEGNEPCFFKTYFS-WDSTK-SVIHGNSFQKKLSLLF 471
            E  S    L  ++EG E   F+++F+ W S + S+   N  ++K++ LF
Sbjct: 318 -EGRSTTTSLVLLTEGLENARFRSFFNKWPSDRWSLAFYNEGREKVAALF 366



 Score = 29.6 bits (65), Expect = 9.8
 Identities = 14/39 (35%), Positives = 23/39 (58%)
 Frame = +1

Query: 181 FCQDDLLTEDLMILDTHGEVFIWIGQCVEPKEKQKAFDI 297
           F +  L  +D+ ILDT  +VF++ G     +EK KA ++
Sbjct: 156 FLRSSLNHDDVFILDTASKVFLFAGCNSSTQEKAKAMEV 194

>VILI_MOUSE (Q62468) Villin-1|
          Length = 826

 Score = 84.0 bits (206), Expect = 4e-16
 Identities = 51/139 (36%), Positives = 73/139 (52%), Gaps = 7/139 (5%)
 Frame = +1

Query: 31  GTXXSAFWFALDGKQSYTS-KPIMQDTIVRDPHLYAFSIRKGRLEVTEIFNFCQDDLLTE 207
           G   + FW AL GK  Y + K + ++  V  P L+  S + GR   TEIF+F QDDL  E
Sbjct: 587 GQEPANFWMALGGKAPYANTKRLQEENQVITPRLFECSNQTGRFLATEIFDFNQDDLEEE 646

Query: 208 DLMILDTHGEVFIWIGQCVEPKEKQKAFDIGQKYIEHAMSIEDLSPYVPLYKVSEGNEPC 387
           D+ +LD   +VF WIG+    +EK+ A    Q+Y++      DL    P+  V +G+EP 
Sbjct: 647 DVFLLDVWDQVFFWIGKHANEEEKKAAATTVQEYLKTHPGNRDLE--TPIIVVKQGHEPP 704

Query: 388 FFKTY------FSWDSTKS 426
            F  +      F W +TKS
Sbjct: 705 TFTGWFLAWDPFKWSNTKS 723

>VILI_HUMAN (P09327) Villin-1|
          Length = 826

 Score = 84.0 bits (206), Expect = 4e-16
 Identities = 50/139 (35%), Positives = 74/139 (53%), Gaps = 7/139 (5%)
 Frame = +1

Query: 31  GTXXSAFWFALDGKQSYTS-KPIMQDTIVRDPHLYAFSIRKGRLEVTEIFNFCQDDLLTE 207
           G   + FW AL GK  Y + K + ++ +V  P L+  S + GR   TEI +F QDDL  +
Sbjct: 587 GQEPANFWMALGGKAPYANTKRLQEENLVITPRLFECSNKTGRFLATEIPDFNQDDLEED 646

Query: 208 DLMILDTHGEVFIWIGQCVEPKEKQKAFDIGQKYIEHAMSIEDLSPYVPLYKVSEGNEPC 387
           D+ +LD   +VF WIG+    +EK+ A    Q+Y++   S  D  P  P+  V +G+EP 
Sbjct: 647 DVFLLDVWDQVFFWIGKHANEEEKKAAATTAQEYLKTHPSGRD--PETPIIVVKQGHEPP 704

Query: 388 FFKTY------FSWDSTKS 426
            F  +      F W +TKS
Sbjct: 705 TFTGWFLAWDPFKWSNTKS 723

>VILI_CHICK (P02640) Villin-1|
          Length = 826

 Score = 81.6 bits (200), Expect = 2e-15
 Identities = 48/134 (35%), Positives = 68/134 (50%), Gaps = 2/134 (1%)
 Frame = +1

Query: 19  IARXGTXXSAFWFALDGKQSYT-SKPIMQDTIVRDPHLYAFSIRKGRLEVTEIFNFCQDD 195
           +   G     FW AL GK SY  SK + ++     P L+  S + GR   TEI +F QDD
Sbjct: 584 VVAEGQEPPEFWVALGGKTSYANSKRLQEENPSVPPRLFECSNKTGRFLATEIVDFTQDD 643

Query: 196 LLTEDLMILDTHGEVFIWIGQCVEPKEKQKAFDIGQKYIEHAMSIEDLSPYVPLYKVSEG 375
           L   D+ +LDT  ++F WIG+     EK+ A +  Q+Y+       DL    P+  V +G
Sbjct: 644 LDENDVYLLDTWDQIFFWIGKGANESEKEAAAETAQEYLRSHPGSRDLD--TPIIVVKQG 701

Query: 376 NEPCFFKTYF-SWD 414
            EP  F  +F +WD
Sbjct: 702 FEPPTFTGWFMAWD 715



 Score = 35.0 bits (79), Expect = 0.23
 Identities = 28/96 (29%), Positives = 44/96 (45%), Gaps = 3/96 (3%)
 Frame = +1

Query: 127 LYAFSIRKGRLEVTEIF--NFCQDDLLTEDLMILDTHG-EVFIWIGQCVEPKEKQKAFDI 297
           LY  S   G L + E+      QD L  ED  ILD  G ++F+W G+    +EKQ+A   
Sbjct: 255 LYHVSDASGNLVIQEVAIRPLTQDMLQHEDCYILDQAGLKIFVWKGKNANKEEKQQAMSR 314

Query: 298 GQKYIEHAMSIEDLSPYVPLYKVSEGNEPCFFKTYF 405
              +I+    +   S    +   ++G+E   F+  F
Sbjct: 315 ALGFIKAKNYLASTS----VETENDGSESAVFRQLF 346

>GELS_CHICK (O93510) Gelsolin precursor (Actin-depolymerizing factor) (ADF)|
            (Brevin) (Homogenin)
          Length = 778

 Score = 80.9 bits (198), Expect = 4e-15
 Identities = 48/126 (38%), Positives = 71/126 (56%), Gaps = 4/126 (3%)
 Frame = +1

Query: 49   FWFALDGKQSYTSKPIMQDTIVR--DPHLYAFSIRKGRLEVTEI-FNFCQDDLLTEDLMI 219
            FW AL GK  Y + P ++D  +    P L+A S + GR  + E+  +  QDDL T+D+MI
Sbjct: 637  FWVALGGKAPYRTSPRLKDKKMDAYPPRLFACSNKSGRFTIEEVPGDLTQDDLATDDVMI 696

Query: 220  LDTHGEVFIWIGQCVEPKEKQKAFDIGQKYIEHAMSIEDLSPYVPLYKVSEGNEPCFFKT 399
            LDT  +VF+WIG+  + +EK +A    ++YIE   +  D     P+  V +G EP  F  
Sbjct: 697  LDTWDQVFVWIGKDAQEEEKTEALKSAKRYIETDPASRD--KRTPVTLVKQGLEPPTFSG 754

Query: 400  YF-SWD 414
            +F  WD
Sbjct: 755  WFLGWD 760



 Score = 35.8 bits (81), Expect = 0.14
 Identities = 27/98 (27%), Positives = 43/98 (43%), Gaps = 5/98 (5%)
 Frame = +1

Query: 127 LYAFSIRKGRLEVTEIFN---FCQDDLLTEDLMILD--THGEVFIWIGQCVEPKEKQKAF 291
           LY  S   G + V+ + +   F Q  L TED  ILD  T G++F+W G+     E++ A 
Sbjct: 296 LYKVSNGAGNMAVSLVADENPFSQAALNTEDCFILDHGTDGKIFVWKGRSANSDERKAAL 355

Query: 292 DIGQKYIEHAMSIEDLSPYVPLYKVSEGNEPCFFKTYF 405
                +I+          +  +  + E  E   FK +F
Sbjct: 356 KTATDFIDKM----GYPKHTQVQVLPESGETPLFKQFF 389

>GELS_MOUSE (P13020) Gelsolin precursor (Actin-depolymerizing factor) (ADF)|
            (Brevin)
          Length = 780

 Score = 79.3 bits (194), Expect = 1e-14
 Identities = 48/132 (36%), Positives = 74/132 (56%), Gaps = 4/132 (3%)
 Frame = +1

Query: 31   GTXXSAFWFALDGKQSYTSKPIMQDTIV--RDPHLYAFSIRKGRLEVTEI-FNFCQDDLL 201
            G+   AFW AL GK +Y + P ++D  +    P L+A S R GR  + E+     Q+DL 
Sbjct: 633  GSEPDAFWEALGGKTAYRTSPRLKDKKMDAHPPRLFACSNRIGRFVIEEVPGELMQEDLA 692

Query: 202  TEDLMILDTHGEVFIWIGQCVEPKEKQKAFDIGQKYIEHAMSIEDLSPYVPLYKVSEGNE 381
            T+D+M+LDT  +VF+W+G+  + +EK +A    ++YIE   +  D     P+  V +G E
Sbjct: 693  TDDVMLLDTWDQVFVWVGKDSQEEEKTEALTSAKRYIETDPANRDRR--TPITVVRQGFE 750

Query: 382  PCFFKTYF-SWD 414
            P  F  +F  WD
Sbjct: 751  PPSFVGWFLGWD 762



 Score = 34.3 bits (77), Expect = 0.40
 Identities = 27/98 (27%), Positives = 42/98 (42%), Gaps = 5/98 (5%)
 Frame = +1

Query: 127 LYAFSIRKGRLEVTEIFN---FCQDDLLTEDLMILD--THGEVFIWIGQCVEPKEKQKAF 291
           LY  S   G + V+ + +   F Q  L +ED  ILD    G++F+W G+    +E++ A 
Sbjct: 298 LYKVSNGAGSMSVSLVADENPFAQGALRSEDCFILDHGRDGKIFVWKGKQANMEERKAAL 357

Query: 292 DIGQKYIEHAMSIEDLSPYVPLYKVSEGNEPCFFKTYF 405
                +I            V    + EG E   FK +F
Sbjct: 358 KTASDFISKMQYPRQTQVSV----LPEGGETPLFKQFF 391

>AVIL_HUMAN (O75366) Advillin (p92)|
          Length = 819

 Score = 79.0 bits (193), Expect = 1e-14
 Identities = 48/135 (35%), Positives = 69/135 (51%), Gaps = 2/135 (1%)
 Frame = +1

Query: 16  NIARXGTXXSAFWFALDGKQSYTS-KPIMQDTIVRDPHLYAFSIRKGRLEVTEIFNFCQD 192
           N    G   + FW  L GK  Y + K + Q+ +     L+  S + G+  VTEI +F QD
Sbjct: 580 NTVAEGQEPAEFWDLLGGKTPYANDKRLQQEILDVQSRLFECSNKTGQFVVTEITDFTQD 639

Query: 193 DLLTEDLMILDTHGEVFIWIGQCVEPKEKQKAFDIGQKYIEHAMSIEDLSPYVPLYKVSE 372
           DL   D+M+LDT  +VF+WIG      EK+ A    Q+Y+    S  D  P  P+  + +
Sbjct: 640 DLNPTDVMLLDTWDQVFLWIGAEANATEKESALATAQQYLHTHPSGRD--PDTPILIIKQ 697

Query: 373 GNEPCFFKTYF-SWD 414
           G EP  F  +F +WD
Sbjct: 698 GFEPPIFTGWFLAWD 712

>GELS_HORSE (Q28372) Gelsolin (Actin-depolymerizing factor) (ADF) (Brevin)|
          Length = 730

 Score = 79.0 bits (193), Expect = 1e-14
 Identities = 46/134 (34%), Positives = 76/134 (56%), Gaps = 4/134 (2%)
 Frame = +1

Query: 31  GTXXSAFWFALDGKQSYTSKPIMQDTIV--RDPHLYAFSIRKGRLEVTEI-FNFCQDDLL 201
           G+   +FW AL GK +Y + P ++D  +    P L+A S + GR  + E+   F Q+DL 
Sbjct: 583 GSEPDSFWEALGGKATYRTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGEFMQEDLA 642

Query: 202 TEDLMILDTHGEVFIWIGQCVEPKEKQKAFDIGQKYIEHAMSIEDLSPYVPLYKVSEGNE 381
           T+D+M+LDT  +VF+W+G+  + +EK +A    ++YI+   +  D     P+  V +G E
Sbjct: 643 TDDVMLLDTWDQVFVWVGKDSQDEEKTEALTSAKRYIDTDPAHRDRR--TPITVVKQGFE 700

Query: 382 PCFFKTYF-SWDST 420
           P  F  +F  WD +
Sbjct: 701 PPSFVGWFLGWDDS 714



 Score = 34.3 bits (77), Expect = 0.40
 Identities = 30/113 (26%), Positives = 49/113 (43%), Gaps = 11/113 (9%)
 Frame = +1

Query: 100 QDTIVRDP------HLYAFSIRKGRLEVTEIFN---FCQDDLLTEDLMILD--THGEVFI 246
           +DT+  D        LY  S   G + V+ + +   F Q  L +ED  ILD    G++F+
Sbjct: 233 EDTVKEDAANRKLAKLYKVSNGAGPMVVSLVADENPFAQGALRSEDCFILDHGKDGKIFV 292

Query: 247 WIGQCVEPKEKQKAFDIGQKYIEHAMSIEDLSPYVPLYKVSEGNEPCFFKTYF 405
           W G+    +E++ A      +I    S  D      +  + EG E   F+ +F
Sbjct: 293 WKGKQANMEERKAALKTASDFI----SKMDYPKQTQVSVLPEGGETPLFRQFF 341

>ADSV_HUMAN (Q9Y6U3) Adseverin (Scinderin)|
          Length = 715

 Score = 78.6 bits (192), Expect = 2e-14
 Identities = 48/135 (35%), Positives = 73/135 (54%), Gaps = 4/135 (2%)
 Frame = +1

Query: 31  GTXXSAFWFALDGKQSYTSKPIMQDTIVRD--PHLYAFSIRKGRLEVTEI-FNFCQDDLL 201
           G     FW +L GK+ Y + P+++ T   D  P LY  S + GR  + EI   F QDDL 
Sbjct: 583 GEEPEEFWNSLGGKKDYQTSPLLE-TQAEDHPPRLYGCSNKTGRFVIEEIPGEFTQDDLA 641

Query: 202 TEDLMILDTHGEVFIWIGQCVEPKEKQKAFDIGQKYIEHAMSIEDLSPYVPLYKVSEGNE 381
            +D+M+LD   ++FIWIG+     EK+++    + Y+E   S  D     P+  + +G+E
Sbjct: 642 EDDVMLLDAWEQIFIWIGKDANEVEKKESLKSAKMYLETDPSGRD--KRTPIVIIKQGHE 699

Query: 382 PCFFKTYF-SWDSTK 423
           P  F  +F  WDS+K
Sbjct: 700 PPTFTGWFLGWDSSK 714



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 28/99 (28%), Positives = 48/99 (48%), Gaps = 6/99 (6%)
 Frame = +1

Query: 127 LYAFSIRKGRLEVTEIFN---FCQDDLLTEDLMILDTHG---EVFIWIGQCVEPKEKQKA 288
           LY  S   G + VT +     F    LL+E+  ILD HG   ++F+W G+   P+E++ A
Sbjct: 251 LYMVSDASGSMRVTVVAEENPFSMAMLLSEECFILD-HGAAKQIFVWKGKDANPQERKAA 309

Query: 289 FDIGQKYIEHAMSIEDLSPYVPLYKVSEGNEPCFFKTYF 405
               +++++      + S    +  + EG E   FK +F
Sbjct: 310 MKTAEEFLQQM----NYSKNTQIQVLPEGGETPIFKQFF 344

>GELS_PIG (P20305) Gelsolin precursor (Actin-depolymerizing factor) (ADF)|
            (Brevin) (Fragment)
          Length = 772

 Score = 77.8 bits (190), Expect = 3e-14
 Identities = 47/132 (35%), Positives = 74/132 (56%), Gaps = 4/132 (3%)
 Frame = +1

Query: 31   GTXXSAFWFALDGKQSYTSKPIMQDTIV--RDPHLYAFSIRKGRLEVTEI-FNFCQDDLL 201
            G+   +FW AL GK +Y + P ++D  +    P L+A S + GR  V E+     Q+DL 
Sbjct: 625  GSEPDSFWEALGGKAAYRTSPRLKDKKMDAHPPRLFACSNKIGRFVVEEVPGELMQEDLA 684

Query: 202  TEDLMILDTHGEVFIWIGQCVEPKEKQKAFDIGQKYIEHAMSIEDLSPYVPLYKVSEGNE 381
            T+D+M+LDT  +VF+W+G+  + +EK +A    ++YIE   +  D     P+  V +G E
Sbjct: 685  TDDVMLLDTWDQVFVWVGKDSQEEEKTEALTSAKRYIETDPANRDRR--TPINVVKQGFE 742

Query: 382  PCFFKTYF-SWD 414
            P  F  +F  WD
Sbjct: 743  PPSFVGWFLGWD 754



 Score = 34.7 bits (78), Expect = 0.31
 Identities = 30/113 (26%), Positives = 49/113 (43%), Gaps = 11/113 (9%)
 Frame = +1

Query: 100 QDTIVRDP------HLYAFSIRKGRLEVTEIFN---FCQDDLLTEDLMILD--THGEVFI 246
           +DT+  D        LY  S   G + V+ + +   F Q  L +ED  ILD    G++F+
Sbjct: 275 EDTVKEDAANRKLAKLYKVSNGAGTMTVSLVADENPFAQGALKSEDCFILDHGKDGKIFV 334

Query: 247 WIGQCVEPKEKQKAFDIGQKYIEHAMSIEDLSPYVPLYKVSEGNEPCFFKTYF 405
           W G+    +E++ A      +I    S  +      +  + EG E   FK +F
Sbjct: 335 WKGKQANTEERKAALKTASDFI----SKMNYPKQTQVSVLPEGGETPLFKQFF 383

>AVIL_MOUSE (O88398) Advillin (p92) (Actin-binding protein DOC6)|
          Length = 819

 Score = 77.0 bits (188), Expect = 5e-14
 Identities = 46/124 (37%), Positives = 68/124 (54%), Gaps = 2/124 (1%)
 Frame = +1

Query: 49  FWFALDGKQSYTS-KPIMQDTIVRDPHLYAFSIRKGRLEVTEIFNFCQDDLLTEDLMILD 225
           FW  L GK +Y + K + Q+T+     L+  S + GR  VTE+ +F Q+DL   D+M+LD
Sbjct: 591 FWDLLGGKTAYANDKRLQQETLDVQVRLFECSNKTGRFLVTEVTDFTQEDLSPGDVMLLD 650

Query: 226 THGEVFIWIGQCVEPKEKQKAFDIGQKYIEHAMSIEDLSPYVPLYKVSEGNEPCFFKTYF 405
           T  +VF+WIG      EK+ A    Q+Y+    S  D  P  P+  + +G EP  F  +F
Sbjct: 651 TWDQVFLWIGAEANATEKKGALSTAQEYLVTHPSGRD--PDTPILIIKQGFEPPTFTGWF 708

Query: 406 -SWD 414
            +WD
Sbjct: 709 LAWD 712

>GELS_HUMAN (P06396) Gelsolin precursor (Actin-depolymerizing factor) (ADF)|
            (Brevin) (AGEL)
          Length = 782

 Score = 77.0 bits (188), Expect = 5e-14
 Identities = 46/132 (34%), Positives = 73/132 (55%), Gaps = 4/132 (3%)
 Frame = +1

Query: 31   GTXXSAFWFALDGKQSYTSKPIMQDTIV--RDPHLYAFSIRKGRLEVTEI-FNFCQDDLL 201
            G+    FW AL GK +Y + P ++D  +    P L+A S + GR  + E+     Q+DL 
Sbjct: 635  GSEPDGFWEALGGKAAYRTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLA 694

Query: 202  TEDLMILDTHGEVFIWIGQCVEPKEKQKAFDIGQKYIEHAMSIEDLSPYVPLYKVSEGNE 381
            T+D+M+LDT  +VF+W+G+  + +EK +A    ++YIE   +  D     P+  V +G E
Sbjct: 695  TDDVMLLDTWDQVFVWVGKDSQEEEKTEALTSAKRYIETDPANRDRR--TPITVVKQGFE 752

Query: 382  PCFFKTYF-SWD 414
            P  F  +F  WD
Sbjct: 753  PPSFVGWFLGWD 764



 Score = 35.8 bits (81), Expect = 0.14
 Identities = 27/98 (27%), Positives = 43/98 (43%), Gaps = 5/98 (5%)
 Frame = +1

Query: 127 LYAFSIRKGRLEVTEIFN---FCQDDLLTEDLMILD--THGEVFIWIGQCVEPKEKQKAF 291
           LY  S   G + V+ + +   F Q  L +ED  ILD    G++F+W G+    +E++ A 
Sbjct: 300 LYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQANTEERKAAL 359

Query: 292 DIGQKYIEHAMSIEDLSPYVPLYKVSEGNEPCFFKTYF 405
                +I       D      +  + EG E   FK +F
Sbjct: 360 KTASDFITKM----DYPKQTQVSVLPEGGETPLFKQFF 393

>ADSV_BOVIN (Q28046) Adseverin (Scinderin) (SC)|
          Length = 715

 Score = 75.5 bits (184), Expect = 2e-13
 Identities = 44/134 (32%), Positives = 70/134 (52%), Gaps = 3/134 (2%)
 Frame = +1

Query: 31  GTXXSAFWFALDGKQSYTSKPIMQDTIV-RDPHLYAFSIRKGRLEVTEI-FNFCQDDLLT 204
           G     FW +L GK+ Y + P+++       P LY  S + GR  + E+   F QDDL  
Sbjct: 583 GKEPEEFWNSLGGKKDYQTSPLLESQAEDHPPRLYGCSNKTGRFIIEEVPGEFTQDDLAE 642

Query: 205 EDLMILDTHGEVFIWIGQCVEPKEKQKAFDIGQKYIEHAMSIEDLSPYVPLYKVSEGNEP 384
           +D+M+LD   ++FIWIG+     EK ++    + Y+E   S  D     P+  + +G+EP
Sbjct: 643 DDVMLLDAWEQIFIWIGKDANEVEKSESLKSAKIYLETDPSGRD--KRTPIVIIKQGHEP 700

Query: 385 CFFKTYF-SWDSTK 423
             F  +F  WDS++
Sbjct: 701 PTFTGWFLGWDSSR 714



 Score = 39.3 bits (90), Expect = 0.012
 Identities = 27/99 (27%), Positives = 49/99 (49%), Gaps = 6/99 (6%)
 Frame = +1

Query: 127 LYAFSIRKGRLEVTEIFN---FCQDDLLTEDLMILDTHG---EVFIWIGQCVEPKEKQKA 288
           LY  S   G ++V+ +     F    LL+E+  ILD HG   ++F+W G+   P+E++ A
Sbjct: 251 LYMVSDASGSMKVSLVAEENPFSMAMLLSEECFILD-HGAAKQIFVWKGKDANPQERKAA 309

Query: 289 FDIGQKYIEHAMSIEDLSPYVPLYKVSEGNEPCFFKTYF 405
               +++++      + S    +  + EG E   FK +F
Sbjct: 310 MKTAEEFLQQM----NYSTNTQIQVLPEGGETPIFKQFF 344

>ADSV_MOUSE (Q60604) Adseverin (Scinderin) (Gelsolin-like protein)|
          Length = 715

 Score = 73.9 bits (180), Expect = 5e-13
 Identities = 45/135 (33%), Positives = 72/135 (53%), Gaps = 4/135 (2%)
 Frame = +1

Query: 31  GTXXSAFWFALDGKQSYTSKPIMQDTIVRD--PHLYAFSIRKGRLEVTEI-FNFCQDDLL 201
           G     FW +L G+  Y + P+++ T   D  P LY  S + GR  + E+   F QDDL 
Sbjct: 583 GKEPEEFWNSLGGRGDYQTSPLLE-TRAEDHPPRLYGCSNKTGRFIIEEVPGEFTQDDLA 641

Query: 202 TEDLMILDTHGEVFIWIGQCVEPKEKQKAFDIGQKYIEHAMSIEDLSPYVPLYKVSEGNE 381
            +D+M+LD   ++FIWIG+     EK+++    + Y+E   S  D     P+  + +G+E
Sbjct: 642 EDDVMLLDAWEQIFIWIGKDANEVEKKESVKSAKMYLETDPSGRD--KRTPIVIIKQGHE 699

Query: 382 PCFFKTYF-SWDSTK 423
           P  F  +F  WDS++
Sbjct: 700 PPTFTGWFLGWDSSR 714



 Score = 40.0 bits (92), Expect = 0.007
 Identities = 28/99 (28%), Positives = 48/99 (48%), Gaps = 6/99 (6%)
 Frame = +1

Query: 127 LYAFSIRKGRLEVTEIFN---FCQDDLLTEDLMILDTHG---EVFIWIGQCVEPKEKQKA 288
           LY  S   G ++VT +     F    LL+E+  ILD HG   ++F+W G+   P+E++ A
Sbjct: 251 LYMVSDASGSMKVTLVAEENPFSMGMLLSEECFILD-HGAAKQIFVWKGKNANPQERKTA 309

Query: 289 FDIGQKYIEHAMSIEDLSPYVPLYKVSEGNEPCFFKTYF 405
               +++++        S    +  + EG E   FK +F
Sbjct: 310 MKTAEEFLQKM----KYSTNTQIQVLPEGGETPIFKQFF 344

>GELS_HOMAM (Q27319) Gelsolin, cytoplasmic (Actin-depolymerizing factor) (ADF)|
          Length = 754

 Score = 72.4 bits (176), Expect = 1e-12
 Identities = 42/130 (32%), Positives = 73/130 (56%), Gaps = 2/130 (1%)
 Frame = +1

Query: 31  GTXXSAFWFALDGKQSYTSKPIMQDTIVRDPHLYAFSIRK-GRLEVTEIFNFCQDDLLTE 207
           G     FW  L GK  Y +   +   ++  P L+  +I   G L V E+ +F Q+DL  +
Sbjct: 601 GEEDDDFWGGLGGKGDYQTARDLDRPLLY-PRLFHCTISPAGCLRVNEMSDFAQEDLNED 659

Query: 208 DLMILDTHGEVFIWIGQCVEPKEKQKAFDIGQKYIEHAMSIEDLSPYVPLYKVSEGNEPC 387
           D+M+LD+  EV++W+GQ  + +EK+KAF + + YI+   +   L   V + ++++G EP 
Sbjct: 660 DVMVLDSGDEVYVWVGQGSDDQEKEKAFTMAENYIKTDPTERTLDATV-ILRINQGEEPA 718

Query: 388 FFKTYF-SWD 414
            F + F +W+
Sbjct: 719 AFTSIFPAWN 728



 Score = 43.1 bits (100), Expect = 9e-04
 Identities = 25/73 (34%), Positives = 36/73 (49%)
 Frame = +1

Query: 187 QDDLLTEDLMILDTHGEVFIWIGQCVEPKEKQKAFDIGQKYIEHAMSIEDLSPYVPLYKV 366
           Q  L + D  +LDT   V++WIG     KEK K+ ++   Y+E     +    Y  + +V
Sbjct: 275 QSMLDSGDCFLLDTGVGVYVWIGSGSSKKEKVKSMELAAGYMEK----KGYPTYTNVQRV 330

Query: 367 SEGNEPCFFKTYF 405
            E  EP  FK YF
Sbjct: 331 VEKAEPAVFKAYF 343

>GELS_XENLA (P14885) Gelsolin (Actin-depolymerizing factor) (ADF) (Brevin)|
           (Fragment)
          Length = 417

 Score = 72.4 bits (176), Expect = 1e-12
 Identities = 44/132 (33%), Positives = 68/132 (51%), Gaps = 3/132 (2%)
 Frame = +1

Query: 31  GTXXSAFWFALDGKQSYTSKPIMQDTI-VRDPHLYAFSIRKGRLEVTEI-FNFCQDDLLT 204
           G     FW AL GK  Y +   ++D +    P L+A S + GR  + E+     QDDL T
Sbjct: 271 GQETDDFWGALGGKADYRTSARLKDKLNAHPPRLFACSNKTGRFIIEEVPGEISQDDLAT 330

Query: 205 EDLMILDTHGEVFIWIGQCVEPKEKQKAFDIGQKYIEHAMSIEDLSPYVPLYKVSEGNE- 381
           +D+M+LDT  +V++W+G   +  EK++A     KYIE   +  D    V + K  +G E 
Sbjct: 331 DDVMLLDTWDQVYVWVGNEAQEDEKKEAIASAYKYIESDPANRDKRTPVAITK--QGFEP 388

Query: 382 PCFFKTYFSWDS 417
           P F   +  W++
Sbjct: 389 PTFIGWFLGWEA 400

>VILL_HUMAN (O15195) Villin-like protein|
          Length = 856

 Score = 71.2 bits (173), Expect = 3e-12
 Identities = 45/131 (34%), Positives = 70/131 (53%), Gaps = 2/131 (1%)
 Frame = +1

Query: 49  FWFALDGKQSYTS-KPIMQDTIVRDPHLYAFSIRKGRLEVTEIFNFCQDDLLTEDLMILD 225
           FW AL G+  Y S K + ++     P L+  S   G L + E+  F Q+DL   D+M+LD
Sbjct: 587 FWEALGGRAPYPSNKRLPEEVPSFQPRLFECSSHMGCLVLAEVGFFSQEDLDKYDIMLLD 646

Query: 226 THGEVFIWIGQCVEPKEKQKAFDIGQKYIEHAMSIEDLSPYVPLYKVSEGNE-PCFFKTY 402
           T  E+F+W+G+     E ++A   GQ+Y++   +    SP  P+  V +G+E P F   +
Sbjct: 647 TWQEIFLWLGEAA--SEWKEAVAWGQEYLKTHPA--GRSPATPIVLVKQGHEPPTFIGWF 702

Query: 403 FSWDSTKSVIH 435
           F+WD  K   H
Sbjct: 703 FTWDPYKWTSH 713

>VILL_MOUSE (Q91YD6) Villin-like protein (EF-6)|
          Length = 859

 Score = 68.6 bits (166), Expect = 2e-11
 Identities = 43/127 (33%), Positives = 70/127 (55%), Gaps = 2/127 (1%)
 Frame = +1

Query: 49  FWFALDGKQSYTS-KPIMQDTIVRDPHLYAFSIRKGRLEVTEIFNFCQDDLLTEDLMILD 225
           FW AL G+  Y S K + ++     P L+  S   G L +TE+  F Q+DL   D+M+LD
Sbjct: 587 FWEALGGRAPYPSNKRLPEEVWSIQPRLFECSSHAGCLVLTEVLFFGQEDLDKYDIMLLD 646

Query: 226 THGEVFIWIGQCVEPKEKQKAFDIGQKYIEHAMSIEDLSPYVPLYKVSEGNEPCFFKTYF 405
           T  E+F+W+G+    + K++A   G +Y+    +   L+   P++ V +G+EP  F  +F
Sbjct: 647 TCQEIFLWLGEAA-GEWKKEAVAWGLEYLRTHPAERSLA--TPIFVVKQGHEPATFTGWF 703

Query: 406 -SWDSTK 423
            +WD  K
Sbjct: 704 VTWDPYK 710

>VILI_DICDI (P36418) Protovillin (100 kDa actin-binding protein)|
          Length = 959

 Score = 63.2 bits (152), Expect = 8e-10
 Identities = 45/156 (28%), Positives = 76/156 (48%), Gaps = 8/156 (5%)
 Frame = +1

Query: 31   GTXXSAFWFALDGKQS-------YTSKPIMQDTIVRDPHLYAFSIRKGRLEVTEIFNFCQ 189
            G   S FW +L+   S       YT    ++    +   L+  S   G  +V EI +F Q
Sbjct: 666  GDETSEFWESLETNSSLSLLKDYYTQLRTVEQE--KKTRLFQCSNNSGVFKVFEIHDFSQ 723

Query: 190  DDLLTEDLMILDTHGEVFIWIGQCVEPKEKQKAFDIGQKYIEHAMSIEDLSPYVPLYKVS 369
            DDL ++D+MILD   ++F+W+G+     EK  A +   +YI +A +        P++ + 
Sbjct: 724  DDLDSDDVMILDNQKQIFVWVGKESSDTEKLMANETALEYIMNAPTHRRDD---PIFTIQ 780

Query: 370  EGNEPCFFK-TYFSWDSTKSVIHGNSFQKKLSLLFG 474
            +G EP  F   + +W   K+    +S++ KLS + G
Sbjct: 781  DGFEPHEFTFNFHAWQVNKT--QQDSYKSKLSAILG 814



 Score = 35.0 bits (79), Expect = 0.23
 Identities = 28/90 (31%), Positives = 44/90 (48%), Gaps = 3/90 (3%)
 Frame = +1

Query: 196 LLTEDLMILDTHGEVFIWIGQCVEPKEKQKAFDIGQKYIEHAMSI--EDLSP-YVPLYKV 366
           L  E   ILD   E+++W+G       K  A D     + +AM +  ED  P + P+ K+
Sbjct: 338 LNAEFCYILDCETELYVWLG-------KASANDQRTVAMANAMDLLHEDNRPSWTPIIKM 390

Query: 367 SEGNEPCFFKTYFSWDSTKSVIHGNSFQKK 456
           ++G+E   FK  F   S    ++ N F+KK
Sbjct: 391 TQGSENTLFKDKFKKGSWGEYVNDN-FEKK 419

>FLII_MOUSE (Q9JJ28) Protein flightless-1 homolog|
          Length = 1271

 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 39/125 (31%), Positives = 60/125 (48%), Gaps = 2/125 (1%)
 Frame = +1

Query: 49   FWFALDGKQSYTSKPIMQDTIVRDPHLYAFSIRKGRLEVTE-IFNFCQDDLLTEDLMILD 225
            FW  +  ++ Y          ++   L+  S  KG   VTE   +FCQDDL  +D+M+LD
Sbjct: 1146 FWVGIGAQKPYDDDA----EYMKHTRLFRCSNEKGYFAVTEKCSDFCQDDLADDDIMLLD 1201

Query: 226  THGEVFIWIGQCVEPKEKQKAFDIGQKYIEHAMSIEDLSPYVPLYKVSEGNEP-CFFKTY 402
               EV++W+G      E + +    Q YI+H  S E   P   L  V +GNE   F + +
Sbjct: 1202 NGQEVYMWVGTQTSQVEIKLSLKACQVYIQHTRSKEHERPR-RLRLVRKGNEQRAFTRCF 1260

Query: 403  FSWDS 417
             +W +
Sbjct: 1261 HAWST 1265



 Score = 37.0 bits (84), Expect = 0.061
 Identities = 37/153 (24%), Positives = 55/153 (35%), Gaps = 20/153 (13%)
 Frame = +1

Query: 31   GTXXSAFWFALDGKQSYTSKPIMQDTIVRDPHLYAFSIRKGRLEVTEI------------ 174
            G     FW  L G+ S     +  D     P LY   +  G LE+ +I            
Sbjct: 696  GQEPPGFWDVLGGEPSEIKNHVPDDFWPPQPKLYKVGLGLGYLELPQINYKLSVEHKKRP 755

Query: 175  -------FNFCQDDLLTEDLMILDTHGEVFIWIGQCVEPKEKQKAFDIGQKYIEHAMSIE 333
                       Q  L T  + ILD   +VFIW+G+      +  A  +GQ+       + 
Sbjct: 756  KVELMPGMRLLQSLLDTRCVYILDCWSDVFIWLGRKSPRLVRAAALKLGQE----LCGML 811

Query: 334  DLSPYVPLYKVSEGNEPCFFKTYF-SWDSTKSV 429
                +  + +  EG E   FK  F +WD   +V
Sbjct: 812  HRPRHTVVSRSLEGTEAQVFKAKFKNWDDVLTV 844

>FLII_DROME (Q24020) Protein flightless-1 (Flightless-I)|
          Length = 1256

 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 40/127 (31%), Positives = 56/127 (44%), Gaps = 2/127 (1%)
 Frame = +1

Query: 49   FWFALDGKQSY-TSKPIMQDTIVRDPHLYAFSIRKGRLEVTE-IFNFCQDDLLTEDLMIL 222
            FW AL G++ Y T    M  T      L+  S  +G   V E   +FCQDDL  +D+MIL
Sbjct: 1132 FWVALGGRKPYDTDAEYMNYT-----RLFRCSNERGYYTVAEKCADFCQDDLADDDIMIL 1186

Query: 223  DTHGEVFIWIGQCVEPKEKQKAFDIGQKYIEHAMSIEDLSPYVPLYKVSEGNEPCFFKTY 402
            D    VF+W+G      E + A+   Q YI+H    +   P      +       F K +
Sbjct: 1187 DNGEHVFLWMGPRCSEVEVKLAYKSAQVYIQHMRIKQPERPRKLFLTMKNKESRRFTKCF 1246

Query: 403  FSWDSTK 423
              W + K
Sbjct: 1247 HGWSAFK 1253



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 35/148 (23%), Positives = 65/148 (43%), Gaps = 11/148 (7%)
 Frame = +1

Query: 19   IARXGTXXSAFW--FALDGKQSYTSKP----IMQDTIVRDPHLYAFSIRKGRLEVTEIF- 177
            + R G   + FW    +  +++  ++P    + +D     P LY   +  G LE+ ++  
Sbjct: 692  LERQGEESAEFWQGLGMTSEEADAAEPPKEHVPEDYQPVQPRLYQVQLGMGYLELPQVEL 751

Query: 178  ---NFCQDDLLTEDLMILDTHGEVFIWIGQCVEPKEKQKAFDIGQKYIEHAMSIEDLSPY 348
                 C   L ++ + ILD + ++F+W G+    K  +       K      ++ D   Y
Sbjct: 752  PEQKLCHTLLNSKHVYILDCYTDLFVWFGK----KSTRLVRAAAVKLSRELFNMMDRPDY 807

Query: 349  VPLYKVSEGNEPCFFKTYFS-WDSTKSV 429
              + +V EGNE   F+T F+ WD   +V
Sbjct: 808  ALVMRVPEGNEMQIFRTKFAGWDEVMAV 835

>FLII_HUMAN (Q13045) Protein flightless-1 homolog|
          Length = 1269

 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 39/125 (31%), Positives = 60/125 (48%), Gaps = 2/125 (1%)
 Frame = +1

Query: 49   FWFALDGKQSYTSKPIMQDTIVRDPHLYAFSIRKGRLEVTE-IFNFCQDDLLTEDLMILD 225
            FW  +  ++ Y          ++   L+  S  KG   VTE   +FCQDDL  +D+M+LD
Sbjct: 1144 FWVGIGAQKPYDDDA----EYMKHTRLFRCSNEKGYFAVTEKCSDFCQDDLADDDIMLLD 1199

Query: 226  THGEVFIWIGQCVEPKEKQKAFDIGQKYIEHAMSIEDLSPYVPLYKVSEGNEP-CFFKTY 402
               EV++W+G      E + +    Q YI+H  S E   P   L  V +GNE   F + +
Sbjct: 1200 NGQEVYMWVGTQTSQVEIKLSLKACQVYIQHMRSKEHERPR-RLRLVRKGNEQHAFTRCF 1258

Query: 403  FSWDS 417
             +W +
Sbjct: 1259 HAWSA 1263



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 39/153 (25%), Positives = 58/153 (37%), Gaps = 20/153 (13%)
 Frame = +1

Query: 31   GTXXSAFWFALDGKQSYTSKPIMQDTIVRDPHLYAFSIRKGRLEVTEI------------ 174
            G     FW AL G+ S   K + +D     P LY   +  G LE+ +I            
Sbjct: 696  GQELPEFWEALGGEPSEIKKHVPEDFWPPQPKLYKVGLGLGYLELPQINYKLSVEHKQRP 755

Query: 175  -------FNFCQDDLLTEDLMILDTHGEVFIWIGQCVEPKEKQKAFDIGQKYIEHAMSIE 333
                       Q  L T  + ILD   +VFIW+G+      +  A  +GQ+       + 
Sbjct: 756  KVELMPRMRLLQSLLDTRCVYILDCWSDVFIWLGRKSPRLVRAAALKLGQE----LCGML 811

Query: 334  DLSPYVPLYKVSEGNEPCFFKTYF-SWDSTKSV 429
                +  + +  EG E   FK  F +WD   +V
Sbjct: 812  HRPRHATVSRSLEGTEAQVFKAKFKNWDDVLTV 844

>GELS_DROME (Q07171) Gelsolin precursor|
          Length = 798

 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 36/130 (27%), Positives = 61/130 (46%), Gaps = 2/130 (1%)
 Frame = +1

Query: 31   GTXXSAFWFALDGKQSYTSKPIMQDTIVRDPHLYAFSIRKGR-LEVTEIFNFCQDDLLTE 207
            G     FW  L+G+  Y          + +  L+   +  G  L+V E+  + Q+DL ++
Sbjct: 646  GAEPDEFWEELNGEGQYDRSLGDDGAPLLESRLFHCHLSSGGFLKVEEVAQYEQEDLDSD 705

Query: 208  DLMILDTHGEVFIWIGQCVEPKEKQKAFDIGQKYIEHAMSIEDLSPYVPLYKVSEGNEPC 387
            D+M+LD   E+++W+G  V  +E  K  D  + Y     +       V + +V +G EP 
Sbjct: 706  DIMLLDAGDEIYLWVGYGVSEEENGKLLDTAKLYFNLEPTARSFDT-VSIIRVPQGKEPR 764

Query: 388  FFKTYF-SWD 414
             FK  F +WD
Sbjct: 765  VFKRMFPNWD 774



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 31/115 (26%), Positives = 51/115 (44%), Gaps = 2/115 (1%)
 Frame = +1

Query: 127 LYAFSIRKGRLEVTEIFN--FCQDDLLTEDLMILDTHGEVFIWIGQCVEPKEKQKAFDIG 300
           LY  S   G+L+V  I      Q  L T +  ILDT   +F+W+G+    KEK  A    
Sbjct: 312 LYKVSDASGKLKVDIIGQKPLTQAMLDTRECFILDTGSGIFVWVGKGATQKEKTDAMAKA 371

Query: 301 QKYIEHAMSIEDLSPYVPLYKVSEGNEPCFFKTYFSWDSTKSVIHGNSFQKKLSL 465
           Q+++      +    +  ++++ EG+E   FK YF       + H    +  L +
Sbjct: 372 QEFLR----TKKYPAWTQIHRIVEGSESAPFKQYFDTWRDAGMSHSRLIRSALGI 422

>FLII_CAEEL (P34268) Protein flightless-1 homolog|
          Length = 1257

 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 40/133 (30%), Positives = 59/133 (44%), Gaps = 2/133 (1%)
 Frame = +1

Query: 31   GTXXSAFWFALDGKQSYTSKPIMQDTIVRDPHLYAFSIRKGRLEVTE-IFNFCQDDLLTE 207
            G     FW  L GK+ Y +      + V+   L+  +  KG   ++E   +FCQDDL  +
Sbjct: 1126 GEENEEFWKVLGGKKKYET----DSSFVKHTRLFRCTNEKGYFAISEKTVDFCQDDLDDD 1181

Query: 208  DLMILDTHGEVFIWIGQCVEPKEKQKAFDIGQKYIEHAMSIEDLSPYVPLYKVSEGNEPC 387
            D+MILD    VF+WIG      E + ++   Q Y        +  P   +  V  G E C
Sbjct: 1182 DIMILDNGDAVFLWIGARSSDIEAKLSYQAAQVYHASMRMKANEKPRKFMLAV-RGRESC 1240

Query: 388  -FFKTYFSWDSTK 423
             F K + +W   K
Sbjct: 1241 RFRKCFHAWSKMK 1253



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 34/131 (25%), Positives = 62/131 (47%), Gaps = 9/131 (6%)
 Frame = +1

Query: 49   FWFALDGKQSYTSKPIMQDT----IVRDPHLYAFSIRKGRLEVTEIF---NFCQDDLL-T 204
            FW AL G        I++      +     LY  +I  G LE+ ++       + D+L +
Sbjct: 713  FWQALTGNPDKPQGAIVEHVPEGFVAERKKLYKVNIGMGFLELPQVELPKGIAKQDMLGS 772

Query: 205  EDLMILDTHGEVFIWIGQCVEPKEKQKAFDIGQKYIEHAMSIEDLSPYVPLYKVSEGNEP 384
            + + +LD++ ++F+WIG+    K  +     GQK +     + D   Y  +Y+ +EG E 
Sbjct: 773  KGVFVLDSNSDIFLWIGK----KANRLLKMAGQKLVVELHQMIDRPDYAQVYRETEGEES 828

Query: 385  CFFKTYFS-WD 414
              F++ F+ WD
Sbjct: 829  MMFRSKFAGWD 839

>VILD_DICDI (Q8WQ85) Villidin|
          Length = 1704

 Score = 57.0 bits (136), Expect = 6e-08
 Identities = 38/144 (26%), Positives = 68/144 (47%), Gaps = 9/144 (6%)
 Frame = +1

Query: 19   IARXGTXXSAFWFALD---GKQSYTSKPIMQDTIVRD-----PHLYAFSIRKGRLEVTEI 174
            I + G+  + FW A +   G+Q Y +  ++Q + +       P  +  S   G +EVTE 
Sbjct: 1477 ILKEGSESNEFWSAFESTGGRQKYFNDIMIQSSSIPTSFTYKPRFFVCSNASGIVEVTEE 1536

Query: 175  FNFCQDDLLTEDLMILDTHGEVFIWIGQCVEPKEKQKAFDIGQKYIEHAMSIEDLSPYVP 354
              F QDDL    + ILD    +++WIG     + K+ + ++   +IE    +     +  
Sbjct: 1537 SPFSQDDLDIGSVCILDVQSHIYLWIGSRATHRTKRASMEVVLNFIE-TSKLGHSKEHTK 1595

Query: 355  LYKVSEGNEPCFFKTYF-SWDSTK 423
            +   +   EP  FK+YF +W ++K
Sbjct: 1596 VLIATPFEEPIGFKSYFRAWCTSK 1619

>SEVE_DICDI (P10733) Severin|
          Length = 362

 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 36/122 (29%), Positives = 55/122 (45%), Gaps = 2/122 (1%)
 Frame = +1

Query: 49  FWFALDGKQSYTSKPIMQDTIVRDPHLYAFSIRKGRLEVTEIFN--FCQDDLLTEDLMIL 222
           FW  L GK +  +K     T   +  LY  S   G L+ +E+      +  L +ED+ I+
Sbjct: 245 FWKLLGGKGAIAAKHETAPT-KSEKVLYKLSDASGSLKFSEVSRGKINKSSLKSEDVFII 303

Query: 223 DTHGEVFIWIGQCVEPKEKQKAFDIGQKYIEHAMSIEDLSPYVPLYKVSEGNEPCFFKTY 402
           D   E++ WIG    P EK+ AF    +Y+ +    E    Y P+ +V E      F+T 
Sbjct: 304 DLGNEIYTWIGSKSSPNEKKTAFSHATQYLVNNKRCE----YTPIVRVLENGTNQSFETL 359

Query: 403 FS 408
            S
Sbjct: 360 LS 361

>CAPG_HUMAN (P40121) Macrophage capping protein (Actin-regulatory protein|
           CAP-G)
          Length = 348

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 26/98 (26%), Positives = 50/98 (51%), Gaps = 5/98 (5%)
 Frame = +1

Query: 127 LYAFSIRKGRLEVTEIFN---FCQDDLLTEDLMILDTH--GEVFIWIGQCVEPKEKQKAF 291
           LY  S   G++ +T++ +   F  + L+++D  +LD    G+++IW G+    KE+Q A 
Sbjct: 251 LYKVSDATGQMNLTKVADSSPFALELLISDDCFVLDNGLCGKIYIWKGRKANEKERQAAL 310

Query: 292 DIGQKYIEHAMSIEDLSPYVPLYKVSEGNEPCFFKTYF 405
            + + +I    S    +P   +  + +G E   FK +F
Sbjct: 311 QVAEGFI----SRMQYAPNTQVEILPQGRESPIFKQFF 344

>CAPG_MOUSE (P24452) Macrophage capping protein (Myc basic motif homolog 1)|
           (Actin-capping protein GCAP39)
          Length = 352

 Score = 39.7 bits (91), Expect = 0.009
 Identities = 25/98 (25%), Positives = 46/98 (46%), Gaps = 5/98 (5%)
 Frame = +1

Query: 127 LYAFSIRKGRLEVTEIFN---FCQDDLLTEDLMILDTH--GEVFIWIGQCVEPKEKQKAF 291
           LY  S   G++ +T++ +   F  + L+ +D  +LD     +++IW G+    KE+Q A 
Sbjct: 255 LYKVSDATGQMNLTKVADSSPFASELLIPDDCFVLDNGLCAQIYIWKGRKANEKERQAAL 314

Query: 292 DIGQKYIEHAMSIEDLSPYVPLYKVSEGNEPCFFKTYF 405
            +   +I         SP   +  + +G E   FK +F
Sbjct: 315 QVADGFISRMR----YSPNTQVEILPQGRESPIFKQFF 348

>QUAI_DROME (Q23989) Villin-like protein quail|
          Length = 887

 Score = 38.9 bits (89), Expect = 0.016
 Identities = 28/92 (30%), Positives = 43/92 (46%), Gaps = 1/92 (1%)
 Frame = +1

Query: 145 RKGRLEVTEIFNFCQDDLLTEDLMILDTHGEVFIWIGQCVEPKEKQKAFDIGQKYIEHAM 324
           ++  L   EI  F Q DL ++   ILDT    ++W+G     +E+  A  I Q Y+++A 
Sbjct: 693 QQSSLRYEEILGFDQQDLSSDCTYILDTGSLTYVWLGSQAPNQERYTA--IAQSYVQNAP 750

Query: 325 SIEDLSPYVPLYKVSEGNEPCFFKTYF-SWDS 417
                     L  V +  EP  FK +F SW +
Sbjct: 751 F--GRRSATALAVVRQFQEPNVFKGFFESWQN 780

>RPOC_RHOS4 (Q3J5S9) DNA-directed RNA polymerase beta' chain (EC 2.7.7.6) (RNAP|
            beta' subunit) (Transcriptase beta' chain) (RNA
            polymerase beta' subunit)
          Length = 1415

 Score = 33.9 bits (76), Expect = 0.52
 Identities = 32/107 (29%), Positives = 47/107 (43%)
 Frame = +1

Query: 217  ILDTHGEVFIWIGQCVEPKEKQKAFDIGQKYIEHAMSIEDLSPYVPLYKVSEGNEPCFFK 396
            ILD+ GE  +  G+ V+  E     ++ QK ++H M      P + L       +   F 
Sbjct: 1262 ILDS-GETTLLKGEHVDKAELD---EVNQKAMDHGMRPAHAEPIL-LGITKASLQTRSFI 1316

Query: 397  TYFSWDSTKSVIHGNSFQKKLSLLFGLRSEVIWGASRSSGNGGPTQR 537
            +  S+  T  V+   S Q K   L GL+  VI G    +G GG T R
Sbjct: 1317 SAASFQETTRVLTEASVQGKRDKLVGLKENVIVGRLIPAGTGGATSR 1363

>S4A11_HUMAN (Q8NBS3) Sodium bicarbonate transporter-like protein 11|
           (Bicarbonate transporter-related protein 1) (Solute
           carrier family 4 member 11)
          Length = 891

 Score = 31.6 bits (70), Expect = 2.6
 Identities = 19/66 (28%), Positives = 35/66 (53%), Gaps = 2/66 (3%)
 Frame = +2

Query: 497 VHLGALVMVDPH--KGHLH*PLYHLHSIHLRSRSRLMIVGLQALVMGPLNVPLHWLLCPM 670
           +H+ AL +V+     GH++  + ++    L S    ++VGL  L+   L VPL W+  P+
Sbjct: 727 LHVRALALVEERVENGHIYDTIVNVKETRLTSLGASVLVGLSLLL---LPVPLQWIPKPV 783

Query: 671 QHSIHL 688
            + + L
Sbjct: 784 LYGLFL 789

>EXOC2_CAEEL (Q22706) Probable exocyst complex component 2 (Exocyst complex|
           component Sec5)
          Length = 884

 Score = 31.6 bits (70), Expect = 2.6
 Identities = 17/59 (28%), Positives = 31/59 (52%)
 Frame = -2

Query: 305 FWPMSNAFCFSFGSTH*PIQIKTSPCVSRIIKSSVNKSSWQKLKISVTSSLPFLIEKAY 129
           FW ++N +     ST  P  I+    +++++ + +N SSW  L   V  +LP ++ K Y
Sbjct: 439 FWKLANTY---HNSTASPDAIQRLEDINQMLTNIINVSSWLILNALVPKALPDMVLKQY 494

>SVIL_MOUSE (Q8K4L3) Supervillin (Archvillin) (p205/p250)|
          Length = 2170

 Score = 30.8 bits (68), Expect = 4.4
 Identities = 37/170 (21%), Positives = 61/170 (35%), Gaps = 38/170 (22%)
 Frame = +1

Query: 49   FWFALDGKQSYTSKPIMQDTIVRDPHLYAFSIRKGRLEVTEIFNFCQDDLLTED------ 210
            FW  L G+ SY S         ++  LY  +I    +E   ++    D L+ +D      
Sbjct: 1489 FWKLLGGQTSYQSAGDP-----KEDELYETAI----IETNCVYRLTDDKLVPDDDYWGKI 1539

Query: 211  ----------LMILDTHGEVFIWIGQCVEPKEKQKAFDIGQKYIEHAMSIE--DLSPYVP 354
                      +++ D   EV++W G+ V   +++ AF + +         E  D++P  P
Sbjct: 1540 PKCSLLQSKEVLVFDFGSEVYVWHGKEVTLAQRKIAFQLAKHLWNGTFDYENCDINPLDP 1599

Query: 355  -------------------LYKVSEGNEPCFFKTYF-SWDSTKSVIHGNS 444
                                 +V+E NE   FK  F  W   K     NS
Sbjct: 1600 GECNPLIPRKGQGRPDWAIFGRVTEHNETILFKEKFLDWTELKRPTEKNS 1649

>SYIC_YEAST (P09436) Isoleucyl-tRNA synthetase, cytoplasmic (EC 6.1.1.5)|
           (Isoleucine--tRNA ligase) (IleRS)
          Length = 1072

 Score = 30.8 bits (68), Expect = 4.4
 Identities = 13/48 (27%), Positives = 25/48 (52%)
 Frame = -1

Query: 243 KDLPVCVKNHQVFSQQIILAKIEDLGNLQSSFPN*EGIQMRISDNSIL 100
           +D   C+KN  +    ++   I+DLG      P+ EG+ ++ +D  I+
Sbjct: 332 EDNAACLKNGVISEDSVLPNAIDDLGRFTKDVPDFEGVYVKDADKLII 379

>SVIL_HUMAN (O95425) Supervillin (Archvillin) (p205/p250)|
          Length = 2214

 Score = 29.6 bits (65), Expect = 9.8
 Identities = 40/184 (21%), Positives = 71/184 (38%), Gaps = 30/184 (16%)
 Frame = +1

Query: 31   GTXXSAFWFALDGKQSYTSKPIMQD--TIVRDPHLYAFSIRKGRLEVTEI---------- 174
            G+    FW AL  +       ++QD  +    P L+  S   G    TE           
Sbjct: 1969 GSEPLGFWDALGRRDRKAYDCMLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVV 2028

Query: 175  --FNFCQDDLLTED---LMILDTHGEVFIWIGQC-VEPK-----------EKQKAFDIGQ 303
                F Q+DL +     L ++D H EV++W G   +E K           +++ A +   
Sbjct: 2029 SSMPFLQEDLYSAPQPALFLVDNHHEVYLWQGWWPIENKITGSARIRWASDRKSAMETVL 2088

Query: 304  KYIEHAMSIEDLSPYVPLYKVSEGNEPCFFKTYF-SWDSTKSVIHGNSFQKKLSLLFGLR 480
            +Y +   +++  +P    Y +  G EP  F   F SW+  + +        ++S    L 
Sbjct: 2089 QYCK-GKNLKKPAP--KSYLIHAGLEPLTFTNMFPSWEHREDIAEITEMDTEVSNQITLV 2145

Query: 481  SEVI 492
             +V+
Sbjct: 2146 EDVL 2149


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 107,791,792
Number of Sequences: 219361
Number of extensions: 2317116
Number of successful extensions: 5732
Number of sequences better than 10.0: 38
Number of HSP's better than 10.0 without gapping: 5460
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5718
length of database: 80,573,946
effective HSP length: 109
effective length of database: 56,663,597
effective search space used: 7422931207
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)