ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | basd16h06 |
|---|---|
| Clone Library Name | barley_pub |
>TMK1_ARATH (P43298) Putative receptor protein kinase TMK1 precursor (EC| 2.7.11.1) Length = 942 Score = 77.0 bits (188), Expect = 3e-14 Identities = 42/119 (35%), Positives = 70/119 (58%), Gaps = 2/119 (1%) Frame = +1 Query: 148 LPLDFVKTITDQFSEQRILGTGAFGIVYKGIMPDGQIITVKKLAENSPIARE--KAFANE 321 + + ++++T+ FS ILG+G FG+VYKG + DG I VK++ EN IA + F +E Sbjct: 576 ISIQVLRSVTNNFSSDNILGSGGFGVVYKGELHDGTKIAVKRM-ENGVIAGKGFAEFKSE 634 Query: 322 VQNIMALHHENVVKLVGYCHEGQKKVVQNNGRYIVADIVESLLCHEYVPKGSLQKNLFE 498 + + + H ++V L+GYC +G +K LL +EY+P+G+L ++LFE Sbjct: 635 IAVLTKVRHRHLVTLLGYCLDGNEK----------------LLVYEYMPQGTLSRHLFE 677
>SRK6_BRAOE (Q09092) Putative serine/threonine-protein kinase receptor| precursor (EC 2.7.11.1) (S-receptor kinase) (SRK) Length = 849 Score = 70.1 bits (170), Expect = 4e-12 Identities = 49/133 (36%), Positives = 71/133 (53%), Gaps = 5/133 (3%) Frame = +1 Query: 148 LPLDFVKTI---TDQFSEQRILGTGAFGIVYKGIMPDGQIITVKKLAENSPIAREKAFAN 318 LPL ++T+ T+ FS LG G FGIVYKG + DG+ I VK+L++ S + F N Sbjct: 513 LPLIEMETVVKATENFSSCNKLGQGGFGIVYKGRLLDGKEIAVKRLSKTS-VQGTDEFMN 571 Query: 319 EVQNIMALHHENVVKLVGYCHEGQKKVVQNNGRYIVADIVESLLCHEYVPKGSLQKNLFE 498 EV I L H N+V+++G C EG +K +L +EY+ SL LF Sbjct: 572 EVTLIARLQHINLVQVLGCCIEGDEK----------------MLIYEYLENLSLDSYLFG 615 Query: 499 VD--TKMDWSTRF 531 +K++W+ RF Sbjct: 616 KTRRSKLNWNERF 628
>PSKR_DAUCA (Q8LPB4) Phytosulfokine receptor precursor (EC 2.7.11.1)| (Phytosulfokine LRR receptor kinase) Length = 1021 Score = 68.9 bits (167), Expect = 8e-12 Identities = 43/132 (32%), Positives = 66/132 (50%), Gaps = 3/132 (2%) Frame = +1 Query: 148 LPLDFVKTITDQFSEQRILGTGAFGIVYKGIMPDGQIITVKKLAENSPIAREKAFANEVQ 327 L LD + T F++ I+G G FG+VYK +PDG + +K+L+ ++ ++ F EV+ Sbjct: 731 LSLDDILKSTSSFNQANIIGCGGFGLVYKATLPDGTKVAIKRLSGDTG-QMDREFQAEVE 789 Query: 328 NIMALHHENVVKLVGYCHEGQKKVVQNNGRYIVADIVESLLCHEYVPKGSLQKNLFE-VD 504 + H N+V L+GYC+ K LL + Y+ GSL L E VD Sbjct: 790 TLSRAQHPNLVHLLGYCNYKNDK----------------LLIYSYMDNGSLDYWLHEKVD 833 Query: 505 --TKMDWSTRFK 534 +DW TR + Sbjct: 834 GPPSLDWKTRLR 845
>PBS1_ARATH (Q9FE20) Serine/threonine-protein kinase PBS1 (EC 2.7.11.1)| (AvrPphB susceptible protein 1) Length = 456 Score = 68.2 bits (165), Expect = 1e-11 Identities = 42/124 (33%), Positives = 63/124 (50%), Gaps = 4/124 (3%) Frame = +1 Query: 175 TDQFSEQRILGTGAFGIVYKGIMPD-GQIITVKKLAENSPIAREKAFANEVQNIMALHHE 351 T F LG G FG VYKG + GQ++ VK+L N + + F EV + LHH Sbjct: 83 TMNFHPDTFLGEGGFGRVYKGRLDSTGQVVAVKQLDRNG-LQGNREFLVEVLMLSLLHHP 141 Query: 352 NVVKLVGYCHEGQKKVVQNNGRYIVADIVESLLCHEYVPKGSLQKNLFEV---DTKMDWS 522 N+V L+GYC +G ++ LL +E++P GSL+ +L ++ +DW+ Sbjct: 142 NLVNLIGYCADGDQR----------------LLVYEFMPLGSLEDHLHDLPPDKEALDWN 185 Query: 523 TRFK 534 R K Sbjct: 186 MRMK 189
>EXS_ARATH (Q9LYN8) Leucine-rich repeat receptor protein kinase EXS precursor| (EC 2.7.11.1) (Extra sporogenous cells protein) (EXCESS MICROSPOROCYTES1 protein) Length = 1192 Score = 68.2 bits (165), Expect = 1e-11 Identities = 43/126 (34%), Positives = 64/126 (50%), Gaps = 6/126 (4%) Frame = +1 Query: 175 TDQFSEQRILGTGAFGIVYKGIMPDGQIITVKKLAENSPIAREKAFANEVQNIMALHHEN 354 TD FS++ I+G G FG VYK +P + + VKKL+E + + F E++ + + H N Sbjct: 914 TDHFSKKNIIGDGGFGTVYKACLPGEKTVAVKKLSE-AKTQGNREFMAEMETLGKVKHPN 972 Query: 355 VVKLVGYCHEGQKKVVQNNGRYIVADIVESLLCHEYVPKGSL------QKNLFEVDTKMD 516 +V L+GYC ++K LL +EY+ GSL Q + EV +D Sbjct: 973 LVSLLGYCSFSEEK----------------LLVYEYMVNGSLDHWLRNQTGMLEV---LD 1013 Query: 517 WSTRFK 534 WS R K Sbjct: 1014 WSKRLK 1019
>BRL3_ARATH (Q9LJF3) Serine/threonine-protein kinase BRI1-like 3 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 3) Length = 1164 Score = 67.8 bits (164), Expect = 2e-11 Identities = 42/124 (33%), Positives = 64/124 (51%), Gaps = 4/124 (3%) Frame = +1 Query: 175 TDQFSEQRILGTGAFGIVYKGIMPDGQIITVKKLAENSPIAREKAFANEVQNIMALHHEN 354 T+ FS ++G+G FG VYK + DG ++ +KKL + + ++ F E++ I + H N Sbjct: 855 TNGFSADSMIGSGGFGDVYKAKLADGSVVAIKKLIQVTG-QGDREFMAEMETIGKIKHRN 913 Query: 355 VVKLVGYCHEGQKKVVQNNGRYIVADIVESLLCHEYVPKGSLQKNLFEVDTK----MDWS 522 +V L+GYC G+ E LL +EY+ GSL+ L E K +DWS Sbjct: 914 LVPLLGYCKIGE----------------ERLLVYEYMKYGSLETVLHEKTKKGGIFLDWS 957 Query: 523 TRFK 534 R K Sbjct: 958 ARKK 961
>CX32_ARATH (P27450) Probable serine/threonine-protein kinase Cx32, chloroplast| precursor (EC 2.7.11.1) Length = 419 Score = 67.0 bits (162), Expect = 3e-11 Identities = 43/134 (32%), Positives = 63/134 (47%), Gaps = 10/134 (7%) Frame = +1 Query: 163 VKTITDQFSEQRILGTGAFGIVYKGIMP----------DGQIITVKKLAENSPIAREKAF 312 +KT T F +LG G FG VY+G + G I+ +K+L S + + Sbjct: 79 LKTATKNFKPDSMLGQGGFGKVYRGWVDATTLAPSRVGSGMIVAIKRLNSES-VQGFAEW 137 Query: 313 ANEVQNIMALHHENVVKLVGYCHEGQKKVVQNNGRYIVADIVESLLCHEYVPKGSLQKNL 492 +EV + L H N+VKL+GYC E + E LL +E++PKGSL+ +L Sbjct: 138 RSEVNFLGMLSHRNLVKLLGYCREDK----------------ELLLVYEFMPKGSLESHL 181 Query: 493 FEVDTKMDWSTRFK 534 F + W R K Sbjct: 182 FRRNDPFPWDLRIK 195
>BRI1_ARATH (O22476) BRASSINOSTEROID INSENSITIVE 1 precursor (EC 2.7.11.1)| (AtBRI1) (Brassinosteroid LRR receptor kinase) Length = 1196 Score = 66.6 bits (161), Expect = 4e-11 Identities = 41/123 (33%), Positives = 62/123 (50%), Gaps = 3/123 (2%) Frame = +1 Query: 175 TDQFSEQRILGTGAFGIVYKGIMPDGQIITVKKLAENSPIAREKAFANEVQNIMALHHEN 354 T+ F ++G+G FG VYK I+ DG + +KKL S ++ F E++ I + H N Sbjct: 880 TNGFHNDSLIGSGGFGDVYKAILKDGSAVAIKKLIHVSG-QGDREFMAEMETIGKIKHRN 938 Query: 355 VVKLVGYCHEGQKKVVQNNGRYIVADIVESLLCHEYVPKGSLQKNLFE---VDTKMDWST 525 +V L+GYC G E LL +E++ GSL+ L + K++WST Sbjct: 939 LVPLLGYCKVGD----------------ERLLVYEFMKYGSLEDVLHDPKKAGVKLNWST 982 Query: 526 RFK 534 R K Sbjct: 983 RRK 985
>NORK_MEDTR (Q8L4H4) Nodulation receptor kinase precursor (EC 2.7.11.1) (Does| not make infections protein 2) (Symbiosis receptor-like kinase) (MtSYMRK) Length = 925 Score = 66.6 bits (161), Expect = 4e-11 Identities = 41/138 (29%), Positives = 71/138 (51%), Gaps = 3/138 (2%) Frame = +1 Query: 124 VLSTLPKNLPLDFVKTITDQFSEQRILGTGAFGIVYKGIMPDGQIITVKKLAENSPIARE 303 + S K L++++ T+Q+ + ++G G FG VY+G + DGQ + VK + S Sbjct: 578 IKSVSVKPFTLEYIEQATEQY--KTLIGEGGFGSVYRGTLDDGQEVAVKVRSSTSTQGTR 635 Query: 304 KAFANEVQNIMALHHENVVKLVGYCHEGQKKVVQNNGRYIVADIVESLLCHEYVPKGSLQ 483 + F NE+ + A+ HEN+V L+GYC+E +++ L + ++ GSL Sbjct: 636 E-FDNELNLLSAIQHENLVPLLGYCNEYDQQI----------------LVYPFMSNGSLL 678 Query: 484 KNLFEVDTK---MDWSTR 528 L+ +K +DW TR Sbjct: 679 DRLYGEASKRKILDWPTR 696
>CRI4_MAIZE (O24585) Putative receptor protein kinase CRINKLY4 precursor (EC| 2.7.11.1) Length = 901 Score = 65.5 bits (158), Expect = 9e-11 Identities = 38/123 (30%), Positives = 65/123 (52%), Gaps = 5/123 (4%) Frame = +1 Query: 175 TDQFSEQRILGTGAFGIVYKGIMPDGQIITVKKLAENSPIAR-EKAFANEVQNIMALHHE 351 T FSE +G G+F V+KGI+ DG ++ VK+ + S + + K F NE+ + L+H Sbjct: 502 TGGFSEDSQVGKGSFSCVFKGILRDGTVVAVKRAIKASDVKKSSKEFHNELDLLSRLNHA 561 Query: 352 NVVKLVGYCHEGQKKVVQNNGRYIVADIVESLLCHEYVPKGSLQKNLFEVD----TKMDW 519 +++ L+GYC +G E LL +E++ GSL ++L D +++W Sbjct: 562 HLLNLLGYCEDGS----------------ERLLVYEFMAHGSLYQHLHGKDPNLKKRLNW 605 Query: 520 STR 528 + R Sbjct: 606 ARR 608
>NORK_PEA (Q8LKZ1) Nodulation receptor kinase precursor (EC 2.7.11.1)| Length = 924 Score = 65.1 bits (157), Expect = 1e-10 Identities = 42/139 (30%), Positives = 73/139 (52%), Gaps = 4/139 (2%) Frame = +1 Query: 124 VLSTLPKNLPLDFVKTITDQFSEQRILGTGAFGIVYKGIMPDGQIITVK-KLAENSPIAR 300 + S K L++++ T+++ + ++G G FG VY+G + DGQ + VK + A ++ R Sbjct: 577 IKSVSVKPFTLEYIELATEKY--KTLIGEGGFGSVYRGTLDDGQEVAVKVRSATSTQGTR 634 Query: 301 EKAFANEVQNIMALHHENVVKLVGYCHEGQKKVVQNNGRYIVADIVESLLCHEYVPKGSL 480 E F NE+ + A+ HEN+V L+GYC+E +++ L + ++ GSL Sbjct: 635 E--FDNELNLLSAIQHENLVPLLGYCNEYDQQI----------------LVYPFMSNGSL 676 Query: 481 QKNLFEVDTK---MDWSTR 528 L+ K +DW TR Sbjct: 677 LDRLYGEPAKRKILDWPTR 695
>RLCK7_ARATH (Q9LQQ8) Probable serine/threonine-protein kinase RLCKVII (EC| 2.7.11.1) Length = 423 Score = 64.7 bits (156), Expect = 2e-10 Identities = 40/124 (32%), Positives = 63/124 (50%), Gaps = 4/124 (3%) Frame = +1 Query: 175 TDQFSEQRILGTGAFGIVYKGIMPD-GQIITVKKLAENSPIAREKAFANEVQNIMALHHE 351 T F LG G FG V+KG + Q++ +K+L N + + F EV + H Sbjct: 100 TGNFRSDCFLGEGGFGKVFKGTIEKLDQVVAIKQLDRNG-VQGIREFVVEVLTLSLADHP 158 Query: 352 NVVKLVGYCHEGQKKVVQNNGRYIVADIVESLLCHEYVPKGSLQKNLFEVDT---KMDWS 522 N+VKL+G+C EG ++ LL +EY+P+GSL+ +L + + +DW+ Sbjct: 159 NLVKLIGFCAEGDQR----------------LLVYEYMPQGSLEDHLHVLPSGKKPLDWN 202 Query: 523 TRFK 534 TR K Sbjct: 203 TRMK 206
>BRI1_LYCES (Q8GUQ5) Brassinosteroid LRR receptor kinase precursor (EC 2.7.11.1)| (tBRI1) (Altered brassinolide sensitivity 1) (Systemin receptor SR160) Length = 1207 Score = 64.7 bits (156), Expect = 2e-10 Identities = 39/123 (31%), Positives = 62/123 (50%), Gaps = 3/123 (2%) Frame = +1 Query: 175 TDQFSEQRILGTGAFGIVYKGIMPDGQIITVKKLAENSPIAREKAFANEVQNIMALHHEN 354 T+ F ++G+G FG VYK + DG ++ +KKL S ++ F E++ I + H N Sbjct: 885 TNGFHNDSLVGSGGFGDVYKAQLKDGSVVAIKKLIHVSG-QGDREFTAEMETIGKIKHRN 943 Query: 355 VVKLVGYCHEGQKKVVQNNGRYIVADIVESLLCHEYVPKGSLQKNLFE---VDTKMDWST 525 +V L+GYC G+ E LL +EY+ GSL+ L + + K++W Sbjct: 944 LVPLLGYCKVGE----------------ERLLVYEYMKYGSLEDVLHDRKKIGIKLNWPA 987 Query: 526 RFK 534 R K Sbjct: 988 RRK 990
>BRL1_ARATH (Q9ZWC8) Serine/threonine-protein kinase BRI1-like 1 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 1) Length = 1166 Score = 64.7 bits (156), Expect = 2e-10 Identities = 40/125 (32%), Positives = 65/125 (52%), Gaps = 5/125 (4%) Frame = +1 Query: 175 TDQFSEQRILGTGAFGIVYKGIMPDGQIITVKKLAENSPIAREKAFANEVQNIMALHHEN 354 T+ FS + ++G+G FG VYK + DG ++ +KKL + ++ F E++ I + H N Sbjct: 856 TNGFSAETMVGSGGFGEVYKAQLRDGSVVAIKKLIRITG-QGDREFMAEMETIGKIKHRN 914 Query: 355 VVKLVGYCHEGQKKVVQNNGRYIVADIVESLLCHEYVPKGSLQKNLFEVDTK-----MDW 519 +V L+GYC G+ E LL +EY+ GSL+ L E +K ++W Sbjct: 915 LVPLLGYCKVGE----------------ERLLVYEYMKWGSLETVLHEKSSKKGGIYLNW 958 Query: 520 STRFK 534 + R K Sbjct: 959 AARKK 963
>BAK1_ARATH (Q94F62) BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1| precursor (EC 2.7.11.1) (BRI1-associated receptor kinase 1) (Somatic embryogenesis receptor-like kinase 3) Length = 615 Score = 63.5 bits (153), Expect = 3e-10 Identities = 42/132 (31%), Positives = 59/132 (44%), Gaps = 3/132 (2%) Frame = +1 Query: 142 KNLPLDFVKTITDQFSEQRILGTGAFGIVYKGIMPDGQIITVKKLAENSPIAREKAFANE 321 K L ++ +D FS + ILG G FG VYKG + DG ++ VK+L E E F E Sbjct: 275 KRFSLRELQVASDNFSNKNILGRGGFGKVYKGRLADGTLVAVKRLKEERTQGGELQFQTE 334 Query: 322 VQNIMALHHENVVKLVGYCHEGQKKVVQNNGRYIVADIVESLLCHEYVPKGSLQKNLF-- 495 V+ I H N+++L G+C E LL + Y+ GS+ L Sbjct: 335 VEMISMAVHRNLLRLRGFC----------------MTPTERLLVYPYMANGSVASCLRER 378 Query: 496 -EVDTKMDWSTR 528 E +DW R Sbjct: 379 PESQPPLDWPKR 390
>BRI1_LYCPE (Q8L899) Systemin receptor SR160 precursor (EC 2.7.11.1)| (Brassinosteroid LRR receptor kinase) Length = 1207 Score = 63.5 bits (153), Expect = 3e-10 Identities = 39/123 (31%), Positives = 61/123 (49%), Gaps = 3/123 (2%) Frame = +1 Query: 175 TDQFSEQRILGTGAFGIVYKGIMPDGQIITVKKLAENSPIAREKAFANEVQNIMALHHEN 354 T+ F ++G+G FG VYK + DG ++ +KKL S ++ F E++ I + H N Sbjct: 885 TNGFHNDSLVGSGGFGDVYKAQLKDGSVVAIKKLIHVSG-QGDREFTAEMETIGKIKHRN 943 Query: 355 VVKLVGYCHEGQKKVVQNNGRYIVADIVESLLCHEYVPKGSLQKNLFE---VDTKMDWST 525 +V L+GYC G+ E LL +EY+ GSL+ L + K++W Sbjct: 944 LVPLLGYCKVGE----------------ERLLVYEYMKYGSLEDVLHDRKKTGIKLNWPA 987 Query: 526 RFK 534 R K Sbjct: 988 RRK 990
>PSKR_ARATH (Q9ZVR7) Putative phytosulfokine receptor precursor (EC 2.7.11.1)| (Phytosulfokine LRR receptor kinase) Length = 1008 Score = 60.8 bits (146), Expect = 2e-09 Identities = 42/134 (31%), Positives = 63/134 (47%), Gaps = 3/134 (2%) Frame = +1 Query: 142 KNLPLDFVKTITDQFSEQRILGTGAFGIVYKGIMPDGQIITVKKLAENSPIAREKAFANE 321 K L D + T+ F + I+G G FG+VYK +PDG+ + +KKL+ + E+ F E Sbjct: 720 KELSYDDLLDSTNSFDQANIIGCGGFGMVYKATLPDGKKVAIKKLSGDCG-QIEREFEAE 778 Query: 322 VQNIMALHHENVVKLVGYCHEGQKKVVQNNGRYIVADIVESLLCHEYVPKGSLQKNLFEV 501 V+ + H N+V L G+C N R LL + Y+ GSL L E Sbjct: 779 VETLSRAQHPNLVLLRGFC-------FYKNDR---------LLIYSYMENGSLDYWLHER 822 Query: 502 D---TKMDWSTRFK 534 + + W TR + Sbjct: 823 NDGPALLKWKTRLR 836
>NAK_ARATH (P43293) Probable serine/threonine-protein kinase NAK (EC 2.7.11.1)| Length = 389 Score = 60.8 bits (146), Expect = 2e-09 Identities = 41/144 (28%), Positives = 68/144 (47%), Gaps = 13/144 (9%) Frame = +1 Query: 142 KNLPLDFVKTITDQFSEQRILGTGAFGIVYKGIMPD----------GQIITVKKLAENSP 291 KN L +K+ T F ++G G FG V+KG + + G +I VK+L + Sbjct: 54 KNFSLSELKSATRNFRPDSVVGEGGFGCVFKGWIDESSLAPSKPGTGIVIAVKRLNQEG- 112 Query: 292 IAREKAFANEVQNIMALHHENVVKLVGYCHEGQKKVVQNNGRYIVADIVESLLCHEYVPK 471 + + E+ + L H N+VKL+GYC E + + LL +E++ + Sbjct: 113 FQGHREWLAEINYLGQLDHPNLVKLIGYCLEEEHR----------------LLVYEFMTR 156 Query: 472 GSLQKNLFEVDT---KMDWSTRFK 534 GSL+ +LF T + W+TR + Sbjct: 157 GSLENHLFRRGTFYQPLSWNTRVR 180
>CLV1_ARATH (Q9SYQ8) Receptor protein kinase CLAVATA1 precursor (EC 2.7.11.1)| Length = 980 Score = 60.8 bits (146), Expect = 2e-09 Identities = 38/129 (29%), Positives = 63/129 (48%), Gaps = 2/129 (1%) Frame = +1 Query: 154 LDFV-KTITDQFSEQRILGTGAFGIVYKGIMPDGQIITVKKLAENSPIAREKAFANEVQN 330 LDF + + + E+ I+G G GIVY+G MP+ + +K+L + F E+Q Sbjct: 681 LDFKSEDVLECLKEENIIGKGGAGIVYRGSMPNNVDVAIKRLVGRGTGRSDHGFTAEIQT 740 Query: 331 IMALHHENVVKLVGYCHEGQKKVVQNNGRYIVADIVESLLCHEYVPKGSLQKNLF-EVDT 507 + + H ++V+L+GY VA+ +LL +EY+P GSL + L Sbjct: 741 LGRIRHRHIVRLLGY----------------VANKDTNLLLYEYMPNGSLGELLHGSKGG 784 Query: 508 KMDWSTRFK 534 + W TR + Sbjct: 785 HLQWETRHR 793
>APK1B_ARATH (P46573) Protein kinase APK1B, chloroplast precursor (EC 2.7.11.1)| Length = 412 Score = 59.3 bits (142), Expect = 7e-09 Identities = 41/137 (29%), Positives = 65/137 (47%), Gaps = 13/137 (9%) Frame = +1 Query: 163 VKTITDQFSEQRILGTGAFGIVYKGIMPD----------GQIITVKKLAENSPIAREKAF 312 +K T F +LG G FG V+KG + + G +I VKKL ++ ++ Sbjct: 62 LKAATRNFRPDSVLGEGGFGSVFKGWIDEQTLTASKPGTGVVIAVKKLNQDGWQGHQEWL 121 Query: 313 ANEVQNIMALHHENVVKLVGYCHEGQKKVVQNNGRYIVADIVESLLCHEYVPKGSLQKNL 492 A EV + H N+VKL+GYC E + + LL +E++P+GSL+ +L Sbjct: 122 A-EVNYLGQFSHPNLVKLIGYCLEDEHR----------------LLVYEFMPRGSLENHL 164 Query: 493 FEVDT---KMDWSTRFK 534 F + + W+ R K Sbjct: 165 FRRGSYFQPLSWTLRLK 181
>IRAK1_HUMAN (P51617) Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1)| (IRAK-1) Length = 712 Score = 59.3 bits (142), Expect = 7e-09 Identities = 44/146 (30%), Positives = 67/146 (45%), Gaps = 9/146 (6%) Frame = +1 Query: 82 PSAMSTSAGGGQPSVLSTLPKNLPLDF------VKTITDQFSEQRILGTGAFGIVYKGIM 243 PS +S G S +S L P F + T FSE+ +G G FG VY+ +M Sbjct: 172 PSPAPSSTKPGPESSVSLLQGARPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVM 231 Query: 244 PDGQIITVKKLAENSPI---AREKAFANEVQNIMALHHENVVKLVGYCHEGQKKVVQNNG 414 + + VK+L EN+ + A +++F EV+ + H N+V GYC + NG Sbjct: 232 RN-TVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQ--------NG 282 Query: 415 RYIVADIVESLLCHEYVPKGSLQKNL 492 Y L + ++P GSL+ L Sbjct: 283 FY--------CLVYGFLPNGSLEDRL 300
>SIRK_ARATH (O64483) Senescence-induced receptor-like serine/threonine-protein| kinase precursor (FLG22-induced receptor-like kinase 1) Length = 876 Score = 57.8 bits (138), Expect = 2e-08 Identities = 35/92 (38%), Positives = 51/92 (55%) Frame = +1 Query: 109 GGQPSVLSTLPKNLPLDFVKTITDQFSEQRILGTGAFGIVYKGIMPDGQIITVKKLAENS 288 G + L T + V IT+ F +R++G G FG VY G++ +G+ + VK L+E S Sbjct: 551 GERNGPLKTAKRYFKYSEVVNITNNF--ERVIGKGGFGKVYHGVI-NGEQVAVKVLSEES 607 Query: 289 PIAREKAFANEVQNIMALHHENVVKLVGYCHE 384 K F EV +M +HH N+ LVGYC+E Sbjct: 608 AQGY-KEFRAEVDLLMRVHHTNLTSLVGYCNE 638
>APK1A_ARATH (Q06548) Protein kinase APK1A, chloroplast precursor (EC 2.7.11.1)| Length = 410 Score = 57.4 bits (137), Expect = 2e-08 Identities = 40/137 (29%), Positives = 64/137 (46%), Gaps = 13/137 (9%) Frame = +1 Query: 163 VKTITDQFSEQRILGTGAFGIVYKGIMPD----------GQIITVKKLAENSPIAREKAF 312 +K+ T F +LG G FG V+KG + + G +I VKKL ++ ++ Sbjct: 61 LKSATRNFRPDSVLGEGGFGCVFKGWIDEKSLTASRPGTGLVIAVKKLNQDGWQGHQEWL 120 Query: 313 ANEVQNIMALHHENVVKLVGYCHEGQKKVVQNNGRYIVADIVESLLCHEYVPKGSLQKNL 492 A EV + H ++VKL+GYC E + + LL +E++P+GSL+ +L Sbjct: 121 A-EVNYLGQFSHRHLVKLIGYCLEDEHR----------------LLVYEFMPRGSLENHL 163 Query: 493 FE---VDTKMDWSTRFK 534 F + W R K Sbjct: 164 FRRGLYFQPLSWKLRLK 180
>KPRO_MAIZE (P17801) Putative receptor protein kinase ZmPK1 precursor (EC| 2.7.11.1) Length = 817 Score = 56.6 bits (135), Expect = 4e-08 Identities = 40/112 (35%), Positives = 55/112 (49%), Gaps = 2/112 (1%) Frame = +1 Query: 202 LGTGAFGIVYKGIMPDGQIITVKKLAENSPIAREKAFANEVQNIMALHHENVVKLVGYCH 381 LG G G VYKG++ D + + VKKL EN +E F E+ I ++H N+V++ G+C Sbjct: 540 LGRGESGTVYKGVLEDDRHVAVKKL-ENVRQGKE-VFQAELSVIGRINHMNLVRIWGFCS 597 Query: 382 EGQKKVVQNNGRYIVADIVESLLCHEYVPKGSLQKNLFEV--DTKMDWSTRF 531 EG + LL EYV GSL LF + +DW RF Sbjct: 598 EGSHR----------------LLVSEYVENGSLANILFSEGGNILLDWEGRF 633
>BRL2_ARATH (Q9ZPS9) Serine/threonine-protein kinase BRI1-like 2 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 2) (Protein VASCULAR HIGHWAY 1) Length = 1143 Score = 55.1 bits (131), Expect = 1e-07 Identities = 33/106 (31%), Positives = 54/106 (50%) Frame = +1 Query: 175 TDQFSEQRILGTGAFGIVYKGIMPDGQIITVKKLAENSPIAREKAFANEVQNIMALHHEN 354 T+ FS ++G G FG V+K + DG + +KKL S ++ F E++ + + H N Sbjct: 835 TNGFSAASMIGHGGFGEVFKATLKDGSSVAIKKLIRLS-CQGDREFMAEMETLGKIKHRN 893 Query: 355 VVKLVGYCHEGQKKVVQNNGRYIVADIVESLLCHEYVPKGSLQKNL 492 +V L+GYC G+ E LL +E++ GSL++ L Sbjct: 894 LVPLLGYCKIGE----------------ERLLVYEFMQYGSLEEVL 923
>IRAK4_MOUSE (Q8R4K2) Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1)| (IRAK-4) Length = 459 Score = 54.3 bits (129), Expect = 2e-07 Identities = 42/135 (31%), Positives = 64/135 (47%), Gaps = 11/135 (8%) Frame = +1 Query: 163 VKTITDQFSEQRI------LGTGAFGIVYKGIMPDGQIITVKKLAENSPIARE---KAFA 315 +K+IT+ F EQ +G G FG+VYKG + + I+ VKKL I+ E + F Sbjct: 173 LKSITNNFDEQPASAGGNRMGEGGFGVVYKGCV-NNTIVAVKKLGAMVEISTEELKQQFD 231 Query: 316 NEVQNIMALHHENVVKLVGYCHEGQKKVVQNNGRYIVADIVESLLCHEYVPKGSLQKNLF 495 E++ + HEN+V+L+G+ +D L + Y+P GSL L Sbjct: 232 QEIKVMATCQHENLVELLGFS----------------SDSDNLCLVYAYMPNGSLLDRLS 275 Query: 496 EVD--TKMDWSTRFK 534 +D + W TR K Sbjct: 276 CLDGTPPLSWHTRCK 290
>IRAK4_HUMAN (Q9NWZ3) Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1)| (IRAK-4) (NY-REN-64 antigen) Length = 460 Score = 52.8 bits (125), Expect = 6e-07 Identities = 40/135 (29%), Positives = 63/135 (46%), Gaps = 11/135 (8%) Frame = +1 Query: 163 VKTITDQFSEQRI------LGTGAFGIVYKGIMPDGQIITVKKLAENSPIARE---KAFA 315 +K +T+ F E+ I +G G FG+VYKG + + + VKKLA I E + F Sbjct: 173 LKNVTNNFDERPISVGGNKMGEGGFGVVYKGYV-NNTTVAVKKLAAMVDITTEELKQQFD 231 Query: 316 NEVQNIMALHHENVVKLVGYCHEGQKKVVQNNGRYIVADIVESLLCHEYVPKGSLQKNLF 495 E++ + HEN+V+L+G+ +G + L + Y+P GSL L Sbjct: 232 QEIKVMAKCQHENLVELLGFSSDGD----------------DLCLVYVYMPNGSLLDRLS 275 Query: 496 EVD--TKMDWSTRFK 534 +D + W R K Sbjct: 276 CLDGTPPLSWHMRCK 290
>IRAK1_MOUSE (Q62406) Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1)| (IRAK-1) (IRAK) (Pelle-like protein kinase) (mPLK) Length = 710 Score = 51.6 bits (122), Expect = 1e-06 Identities = 41/146 (28%), Positives = 65/146 (44%), Gaps = 9/146 (6%) Frame = +1 Query: 82 PSAMSTSAGGGQPSVLSTLPKNLPLDF------VKTITDQFSEQRILGTGAFGIVYKGIM 243 PS+ +S S +S L + P F + T FSE+ +G G FG VY+ +M Sbjct: 172 PSSAPSSTKSSPESPVSGLQRAHPSPFCWPFCEISQGTCNFSEELRIGEGGFGCVYRAVM 231 Query: 244 PDGQIITVKKLAENSPIAR---EKAFANEVQNIMALHHENVVKLVGYCHEGQKKVVQNNG 414 + VK+L E + + +++F EV+ + H N+V GYC E +G Sbjct: 232 RN-TTYAVKRLKEEADLEWTMVKQSFLTEVEQLSRFRHPNIVDFAGYCAE--------SG 282 Query: 415 RYIVADIVESLLCHEYVPKGSLQKNL 492 Y L + ++P GSL+ L Sbjct: 283 LY--------CLVYGFLPNGSLEDQL 300
>RLK5_ARATH (P47735) Receptor-like protein kinase 5 precursor (EC 2.7.11.1)| Length = 999 Score = 49.7 bits (117), Expect = 5e-06 Identities = 33/112 (29%), Positives = 52/112 (46%), Gaps = 9/112 (8%) Frame = +1 Query: 172 ITDQFSEQRILGTGAFGIVYKGIMPDGQIITVKKLAE---------NSPIAREKAFANEV 324 I D E+ ++G G+ G VYK + G+++ VKKL + +S FA EV Sbjct: 679 IADCLDEKNVIGFGSSGKVYKVELRGGEVVAVKKLNKSVKGGDDEYSSDSLNRDVFAAEV 738 Query: 325 QNIMALHHENVVKLVGYCHEGQKKVVQNNGRYIVADIVESLLCHEYVPKGSL 480 + + + H+++V+L C G K LL +EY+P GSL Sbjct: 739 ETLGTIRHKSIVRLWCCCSSGDCK----------------LLVYEYMPNGSL 774
>FER_HUMAN (P16591) Proto-oncogene tyrosine-protein kinase FER (EC 2.7.10.2)| (p94-FER) (c-FER) Length = 822 Score = 48.1 bits (113), Expect = 2e-05 Identities = 24/64 (37%), Positives = 34/64 (53%) Frame = +1 Query: 199 ILGTGAFGIVYKGIMPDGQIITVKKLAENSPIAREKAFANEVQNIMALHHENVVKLVGYC 378 +LG G FG VYKG + D + VK E+ P + F E + + H N+VKL+G C Sbjct: 568 LLGKGNFGEVYKGTLKDKTSVAVKTCKEDLPQELKIKFLQEAKILKQYDHPNIVKLIGVC 627 Query: 379 HEGQ 390 + Q Sbjct: 628 TQRQ 631
>YSK4_HUMAN (Q56UN5) SPS1/STE20-related protein kinase YSK4 (EC 2.7.11.1)| (Regulated in COPD, protein kinase) Length = 1328 Score = 47.8 bits (112), Expect = 2e-05 Identities = 27/70 (38%), Positives = 42/70 (60%), Gaps = 5/70 (7%) Frame = +1 Query: 184 FSEQRILGTGAFGIVYKGIMPDGQIITVKKLA--ENSPIAREKAF---ANEVQNIMALHH 348 +++ ILG GA+G VY G+ GQ+I VK++A ++ +A EK + EV + AL H Sbjct: 1061 WTKGEILGKGAYGTVYCGLTSQGQLIAVKQVALDTSNKLAAEKEYRKLQEEVDLLKALKH 1120 Query: 349 ENVVKLVGYC 378 N+V +G C Sbjct: 1121 VNIVAYLGTC 1130
>FLK_RAT (P09760) Tyrosine-protein kinase FLK (EC 2.7.10.2) (Fragment)| Length = 323 Score = 47.8 bits (112), Expect = 2e-05 Identities = 24/64 (37%), Positives = 34/64 (53%) Frame = +1 Query: 199 ILGTGAFGIVYKGIMPDGQIITVKKLAENSPIAREKAFANEVQNIMALHHENVVKLVGYC 378 +LG G FG VYKG + D + VK E+ P + F E + + H N+VKL+G C Sbjct: 69 LLGKGNFGEVYKGTLKDKTPVAVKTCKEDLPQELKIKFLQEAKILKQYDHPNIVKLIGVC 128 Query: 379 HEGQ 390 + Q Sbjct: 129 TQRQ 132
>ROS_CHICK (P08941) Proto-oncogene tyrosine-protein kinase ROS precursor (EC| 2.7.10.1) (c-ros-1) Length = 2311 Score = 46.2 bits (108), Expect = 6e-05 Identities = 30/113 (26%), Positives = 56/113 (49%), Gaps = 8/113 (7%) Frame = +1 Query: 127 LSTLPKNLPLDFVKTIT-DQFSEQRILGTGAFGIVYKG----IMPDG---QIITVKKLAE 282 +STLP ++ + D+ + ++LG+GAFG VY+G I+ DG + VK L Sbjct: 1941 VSTLPSQAEIESLPAFPRDKLNLHKLLGSGAFGEVYEGTALDILADGSGESRVAVKTLKR 2000 Query: 283 NSPIAREKAFANEVQNIMALHHENVVKLVGYCHEGQKKVVQNNGRYIVADIVE 441 + + F E + H +++KL+G C + N +Y++ +++E Sbjct: 2001 GATDQEKSEFLKEAHLMSKFDHPHILKLLGVC-------LLNEPQYLILELME 2046
>RPK1_IPONI (P93194) Receptor-like protein kinase precursor (EC 2.7.11.1)| Length = 1109 Score = 46.2 bits (108), Expect = 6e-05 Identities = 31/127 (24%), Positives = 55/127 (43%), Gaps = 2/127 (1%) Frame = +1 Query: 154 LDFVKTITDQFSEQRILGTGAFGIVYKGIMPDGQIITVKKLAENSPIAREKAFANEVQNI 333 L+ V T+ +++ ++G GA G +YK + ++ VKKL + E++ I Sbjct: 806 LNKVLEATENLNDKYVIGKGAHGTIYKATLSPDKVYAVKKLVFTGIKNGSVSMVREIETI 865 Query: 334 MALHHENVVKLVGYCHEGQKKVVQNNGRYIVADIVESLLCHEYVPKGSLQKNLFEVD--T 507 + H N++KL + + L+ + Y+ GSL L E + Sbjct: 866 GKVRHRNLIKLEEFWLRKE----------------YGLILYTYMENGSLHDILHETNPPK 909 Query: 508 KMDWSTR 528 +DWSTR Sbjct: 910 PLDWSTR 916
>ROS_AVISU (P00529) Tyrosine-protein kinase transforming protein ros (EC| 2.7.10.1) Length = 402 Score = 46.2 bits (108), Expect = 6e-05 Identities = 30/113 (26%), Positives = 56/113 (49%), Gaps = 8/113 (7%) Frame = +1 Query: 127 LSTLPKNLPLDFVKTIT-DQFSEQRILGTGAFGIVYKG----IMPDG---QIITVKKLAE 282 +STLP ++ + D+ + ++LG+GAFG VY+G I+ DG + VK L Sbjct: 78 VSTLPSQAEIESLPAFPRDKLNLHKLLGSGAFGEVYEGTALDILADGSGESRVAVKTLKR 137 Query: 283 NSPIAREKAFANEVQNIMALHHENVVKLVGYCHEGQKKVVQNNGRYIVADIVE 441 + + F E + H +++KL+G C + N +Y++ +++E Sbjct: 138 GATDQEKSEFLKEAHLMSKFDHPHILKLLGVC-------LLNEPQYLILELME 183
>ROR1_DROME (Q24488) Tyrosine-protein kinase transmembrane receptor Ror| precursor (EC 2.7.10.1) (dRor) Length = 685 Score = 46.2 bits (108), Expect = 6e-05 Identities = 26/61 (42%), Positives = 38/61 (62%), Gaps = 4/61 (6%) Frame = +1 Query: 202 LGTGAFGIVYKG--IMPDGQIITV--KKLAENSPIAREKAFANEVQNIMALHHENVVKLV 369 LG GAFG VYKG + P+ ITV K L EN+ + ++ F E++ I L H+N+V ++ Sbjct: 416 LGEGAFGKVYKGQLLQPNKTTITVAIKALKENASVKTQQDFKREIELISDLKHQNIVCIL 475 Query: 370 G 372 G Sbjct: 476 G 476
>TYK2_MOUSE (Q9R117) Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)| Length = 1180 Score = 45.8 bits (107), Expect = 7e-05 Identities = 42/148 (28%), Positives = 62/148 (41%), Gaps = 5/148 (3%) Frame = +1 Query: 64 PQXLVQPSAMSTSAGGGQPSVLSTLPKNLPLDFVKTITDQFSEQRILGTGAFGIVYKGIM 243 PQ LV SA+++ + P+V ++K I D LG G FG V Sbjct: 864 PQNLVGTSAVNSDSPASDPTVFHKR-------YLKKIRD-------LGEGHFGKVSLYCY 909 Query: 244 PD-----GQIITVKKLAENSPIAREKAFANEVQNIMALHHENVVKLVGYCHEGQKKVVQN 408 G+++ VK L E + E++ + L+HE++VK G C + +K VQ Sbjct: 910 DPTNDGTGEMVAVKALKEGCGPQLRSGWQREIEILRTLYHEHIVKYKGCCEDQGEKSVQ- 968 Query: 409 NGRYIVADIVESLLCHEYVPKGSLQKNL 492 L EYVP GSL+ L Sbjct: 969 -------------LVMEYVPLGSLRDYL 983
>XMRK_XIPMA (P13388) Melanoma receptor tyrosine-protein kinase precursor (EC| 2.7.10.1) Length = 1167 Score = 45.1 bits (105), Expect = 1e-04 Identities = 25/71 (35%), Positives = 41/71 (57%), Gaps = 5/71 (7%) Frame = +1 Query: 181 QFSEQRILGTGAFGIVYKGIM-PDGQII----TVKKLAENSPIAREKAFANEVQNIMALH 345 +F + R+LG+GAFG VYKG+ PDG+ I +K L E + + +E + ++ Sbjct: 709 EFKKDRVLGSGAFGTVYKGLWNPDGENIRIPVAIKVLREATSPKVNQEVLDEAYVMASVD 768 Query: 346 HENVVKLVGYC 378 H +V +L+G C Sbjct: 769 HPHVCRLLGIC 779
>GSK3B_RAT (P18266) Glycogen synthase kinase-3 beta (EC 2.7.11.26) (GSK-3| beta) (Factor A) (FA) Length = 420 Score = 44.7 bits (104), Expect = 2e-04 Identities = 35/128 (27%), Positives = 70/128 (54%), Gaps = 8/128 (6%) Frame = +1 Query: 37 PQCWXFSSSPQXLVQPSA-----MSTSAGGGQPSVLSTLPKNLPLDFVKTITDQFSEQRI 201 P+ F+ S + + QPSA +S G + + + P P D + ++ +++ ++ Sbjct: 5 PRTTSFAESCKPVQQPSAFGSMKVSRDKDGSKVTTVVATPGQGP-DRPQEVS--YTDTKV 61 Query: 202 LGTGAFGIVYKGIMPD-GQIITVKKLAENSPIAREKAFAN-EVQNIMALHHENVVKLVGY 375 +G G+FG+VY+ + D G+++ +KK + ++K F N E+Q + L H N+V+L + Sbjct: 62 IGNGSFGVVYQAKLCDSGELVAIKK------VLQDKRFKNRELQIMRKLDHCNIVRLRYF 115 Query: 376 CH-EGQKK 396 + G+KK Sbjct: 116 FYSSGEKK 123
>GSK3B_MOUSE (Q9WV60) Glycogen synthase kinase-3 beta (EC 2.7.11.26) (GSK-3| beta) Length = 420 Score = 44.7 bits (104), Expect = 2e-04 Identities = 35/128 (27%), Positives = 70/128 (54%), Gaps = 8/128 (6%) Frame = +1 Query: 37 PQCWXFSSSPQXLVQPSA-----MSTSAGGGQPSVLSTLPKNLPLDFVKTITDQFSEQRI 201 P+ F+ S + + QPSA +S G + + + P P D + ++ +++ ++ Sbjct: 5 PRTTSFAESCKPVQQPSAFGSMKVSRDKDGSKVTTVVATPGQGP-DRPQEVS--YTDTKV 61 Query: 202 LGTGAFGIVYKGIMPD-GQIITVKKLAENSPIAREKAFAN-EVQNIMALHHENVVKLVGY 375 +G G+FG+VY+ + D G+++ +KK + ++K F N E+Q + L H N+V+L + Sbjct: 62 IGNGSFGVVYQAKLCDSGELVAIKK------VLQDKRFKNRELQIMRKLDHCNIVRLRYF 115 Query: 376 CH-EGQKK 396 + G+KK Sbjct: 116 FYSSGEKK 123
>GSK3B_HUMAN (P49841) Glycogen synthase kinase-3 beta (EC 2.7.11.26) (GSK-3| beta) Length = 420 Score = 44.7 bits (104), Expect = 2e-04 Identities = 35/128 (27%), Positives = 70/128 (54%), Gaps = 8/128 (6%) Frame = +1 Query: 37 PQCWXFSSSPQXLVQPSA-----MSTSAGGGQPSVLSTLPKNLPLDFVKTITDQFSEQRI 201 P+ F+ S + + QPSA +S G + + + P P D + ++ +++ ++ Sbjct: 5 PRTTSFAESCKPVQQPSAFGSMKVSRDKDGSKVTTVVATPGQGP-DRPQEVS--YTDTKV 61 Query: 202 LGTGAFGIVYKGIMPD-GQIITVKKLAENSPIAREKAFAN-EVQNIMALHHENVVKLVGY 375 +G G+FG+VY+ + D G+++ +KK + ++K F N E+Q + L H N+V+L + Sbjct: 62 IGNGSFGVVYQAKLCDSGELVAIKK------VLQDKRFKNRELQIMRKLDHCNIVRLRYF 115 Query: 376 CH-EGQKK 396 + G+KK Sbjct: 116 FYSSGEKK 123
>ERBB4_HUMAN (Q15303) Receptor tyrosine-protein kinase erbB-4 precursor (EC| 2.7.10.1) (p180erbB4) (Tyrosine kinase-type cell surface receptor HER4) Length = 1308 Score = 44.3 bits (103), Expect = 2e-04 Identities = 27/87 (31%), Positives = 46/87 (52%), Gaps = 5/87 (5%) Frame = +1 Query: 133 TLPKNLPLDFVKTITDQFSEQRILGTGAFGIVYKGI-MPDGQI----ITVKKLAENSPIA 297 T P L +K + ++LG+GAFG VYKGI +P+G+ + +K L E + Sbjct: 703 TAPNQAQLRILKET--ELKRVKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPK 760 Query: 298 REKAFANEVQNIMALHHENVVKLVGYC 378 F +E + ++ H ++V+L+G C Sbjct: 761 ANVEFMDEALIMASMDHPHLVRLLGVC 787
>ERBB_AVIEU (P11273) Tyrosine-protein kinase transforming protein erbB (EC| 2.7.10.1) Length = 540 Score = 43.9 bits (102), Expect = 3e-04 Identities = 23/71 (32%), Positives = 43/71 (60%), Gaps = 5/71 (7%) Frame = +1 Query: 181 QFSEQRILGTGAFGIVYKGI-MPDGQIIT----VKKLAENSPIAREKAFANEVQNIMALH 345 +F + ++LG GAFG VYKG+ +P+G+ +T +K+L E + K +E + ++ Sbjct: 131 EFKKVKVLGFGAFGTVYKGLWIPEGEKVTIPVAIKELREATSPKANKEILDEAYVMASVD 190 Query: 346 HENVVKLVGYC 378 + +V +L+G C Sbjct: 191 NPHVCRLLGIC 201
>ERBB4_RAT (Q62956) Receptor tyrosine-protein kinase erbB-4 precursor (EC| 2.7.10.1) Length = 1308 Score = 43.9 bits (102), Expect = 3e-04 Identities = 27/87 (31%), Positives = 46/87 (52%), Gaps = 5/87 (5%) Frame = +1 Query: 133 TLPKNLPLDFVKTITDQFSEQRILGTGAFGIVYKGI-MPDGQI----ITVKKLAENSPIA 297 T P L +K + ++LG+GAFG VYKGI +P+G+ + +K L E + Sbjct: 703 TAPNQAQLRILKET--ELKRVKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPK 760 Query: 298 REKAFANEVQNIMALHHENVVKLVGYC 378 F +E + ++ H ++V+L+G C Sbjct: 761 ANVEFMDEALIMASVDHPHLVRLLGVC 787
>ERBB_ALV (P00534) Tyrosine-protein kinase transforming protein erbB (EC| 2.7.10.1) Length = 634 Score = 43.1 bits (100), Expect = 5e-04 Identities = 22/71 (30%), Positives = 43/71 (60%), Gaps = 5/71 (7%) Frame = +1 Query: 181 QFSEQRILGTGAFGIVYKGI-MPDGQ----IITVKKLAENSPIAREKAFANEVQNIMALH 345 +F + ++LG+GAFG VYKG+ +P+G+ + +K+L E + K +E + ++ Sbjct: 131 EFKKVKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVD 190 Query: 346 HENVVKLVGYC 378 + +V +L+G C Sbjct: 191 NPHVCRLLGIC 201
>INSR_XENLA (Q9PVZ4) Insulin receptor precursor (EC 2.7.10.1) (IR) (Xe-InsR)| (XTK-1b) [Contains: Insulin receptor alpha subunit; Insulin receptor beta subunit] Length = 1362 Score = 43.1 bits (100), Expect = 5e-04 Identities = 32/101 (31%), Positives = 52/101 (51%), Gaps = 6/101 (5%) Frame = +1 Query: 118 PSVLSTLPKNLPLDFVKTITDQFSEQRILGTGAFGIVYKGIMPD---GQ---IITVKKLA 279 P LS +P D + D+ + R LG G+FG+VY+GI D G+ + VK + Sbjct: 991 PEYLSASEVYIP-DEWEVPRDKINLLRELGQGSFGMVYEGIAKDIIKGEPEVRVAVKTVN 1049 Query: 280 ENSPIAREKAFANEVQNIMALHHENVVKLVGYCHEGQKKVV 402 E++ + F NE + A + +VV+L+G +GQ +V Sbjct: 1050 ESASLRERIEFLNEASVMKAFNCHHVVRLLGVVSKGQPTLV 1090
>JAK2_RAT (Q62689) Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2)| (JAK-2) Length = 1132 Score = 43.1 bits (100), Expect = 5e-04 Identities = 34/122 (27%), Positives = 60/122 (49%), Gaps = 10/122 (8%) Frame = +1 Query: 181 QFSEQRI-----LGTGAFGIV----YKGIMPD-GQIITVKKLAENSPIAREKAFANEVQN 330 QF E+ + LG G FG V Y + + G+++ VKKL ++S + F E++ Sbjct: 843 QFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKL-QHSTEEHLRDFEREIEI 901 Query: 331 IMALHHENVVKLVGYCHEGQKKVVQNNGRYIVADIVESLLCHEYVPKGSLQKNLFEVDTK 510 + +L H+N+VK G C+ ++ ++ L EY+P GSL+ L + + Sbjct: 902 LKSLQHDNIVKYKGVCYSAGRRNLR--------------LIMEYLPYGSLRDYLQKHKER 947 Query: 511 MD 516 +D Sbjct: 948 ID 949
>JAK2_HUMAN (O60674) Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2)| (JAK-2) Length = 1132 Score = 43.1 bits (100), Expect = 5e-04 Identities = 34/122 (27%), Positives = 60/122 (49%), Gaps = 10/122 (8%) Frame = +1 Query: 181 QFSEQRI-----LGTGAFGIV----YKGIMPD-GQIITVKKLAENSPIAREKAFANEVQN 330 QF E+ + LG G FG V Y + + G+++ VKKL ++S + F E++ Sbjct: 843 QFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKL-QHSTEEHLRDFEREIEI 901 Query: 331 IMALHHENVVKLVGYCHEGQKKVVQNNGRYIVADIVESLLCHEYVPKGSLQKNLFEVDTK 510 + +L H+N+VK G C+ ++ ++ L EY+P GSL+ L + + Sbjct: 902 LKSLQHDNIVKYKGVCYSAGRRNLK--------------LIMEYLPYGSLRDYLQKHKER 947 Query: 511 MD 516 +D Sbjct: 948 ID 949
>EGFR_DROME (P04412) Epidermal growth factor receptor precursor (EC 2.7.10.1)| (Egfr) (Gurken receptor) (Protein torpedo) (Drosophila relative of ERBB) Length = 1426 Score = 43.1 bits (100), Expect = 5e-04 Identities = 27/96 (28%), Positives = 50/96 (52%), Gaps = 8/96 (8%) Frame = +1 Query: 139 PKNLPLDFVKTITDQFSEQR---ILGTGAFGIVYKGI-MPDGQ----IITVKKLAENSPI 294 P N+ + K + +E R +LG GAFG VYKG+ +P+G+ + +K+L +++ Sbjct: 920 PSNIGANLCKLRIVKDAELRKGGVLGMGAFGRVYKGVWVPEGENVKIPVAIKELLKSTGA 979 Query: 295 AREKAFANEVQNIMALHHENVVKLVGYCHEGQKKVV 402 + F E + + H N++KL+ C Q ++ Sbjct: 980 ESSEEFLREAYIMASEEHVNLLKLLAVCMSSQMMLI 1015
>JAK2_MOUSE (Q62120) Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2)| (JAK-2) Length = 1129 Score = 43.1 bits (100), Expect = 5e-04 Identities = 34/122 (27%), Positives = 60/122 (49%), Gaps = 10/122 (8%) Frame = +1 Query: 181 QFSEQRI-----LGTGAFGIV----YKGIMPD-GQIITVKKLAENSPIAREKAFANEVQN 330 QF E+ + LG G FG V Y + + G+++ VKKL ++S + F E++ Sbjct: 843 QFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKL-QHSTEEHLRDFEREIEI 901 Query: 331 IMALHHENVVKLVGYCHEGQKKVVQNNGRYIVADIVESLLCHEYVPKGSLQKNLFEVDTK 510 + +L H+N+VK G C+ ++ ++ L EY+P GSL+ L + + Sbjct: 902 LKSLQHDNIVKYKGVCYSAGRRNLR--------------LIMEYLPYGSLRDYLQKHKER 947 Query: 511 MD 516 +D Sbjct: 948 ID 949
>ERBB2_MESAU (Q60553) Receptor tyrosine-protein kinase erbB-2 precursor (EC| 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) Length = 1254 Score = 42.7 bits (99), Expect = 6e-04 Identities = 25/66 (37%), Positives = 37/66 (56%), Gaps = 5/66 (7%) Frame = +1 Query: 196 RILGTGAFGIVYKGI-MPDGQ----IITVKKLAENSPIAREKAFANEVQNIMALHHENVV 360 ++LG+GAFG VYKGI +PDG+ + +K L EN+ K +E + L V Sbjct: 724 KVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGLGSPYVS 783 Query: 361 KLVGYC 378 +L+G C Sbjct: 784 RLLGIC 789
>EGFR_MOUSE (Q01279) Epidermal growth factor receptor precursor (EC 2.7.10.1)| Length = 1210 Score = 42.7 bits (99), Expect = 6e-04 Identities = 22/71 (30%), Positives = 43/71 (60%), Gaps = 5/71 (7%) Frame = +1 Query: 181 QFSEQRILGTGAFGIVYKGI-MPDGQ----IITVKKLAENSPIAREKAFANEVQNIMALH 345 +F + ++LG+GAFG VYKG+ +P+G+ + +K+L E + K +E + ++ Sbjct: 713 EFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVD 772 Query: 346 HENVVKLVGYC 378 + +V +L+G C Sbjct: 773 NPHVCRLLGIC 783
>EGFR_HUMAN (P00533) Epidermal growth factor receptor precursor (EC 2.7.10.1)| (Receptor tyrosine-protein kinase ErbB-1) Length = 1210 Score = 42.7 bits (99), Expect = 6e-04 Identities = 22/71 (30%), Positives = 43/71 (60%), Gaps = 5/71 (7%) Frame = +1 Query: 181 QFSEQRILGTGAFGIVYKGI-MPDGQ----IITVKKLAENSPIAREKAFANEVQNIMALH 345 +F + ++LG+GAFG VYKG+ +P+G+ + +K+L E + K +E + ++ Sbjct: 711 EFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVD 770 Query: 346 HENVVKLVGYC 378 + +V +L+G C Sbjct: 771 NPHVCRLLGIC 781
>ERBB_AVIER (P00535) Tyrosine-protein kinase transforming protein erbB (EC| 2.7.10.1) Length = 604 Score = 42.7 bits (99), Expect = 6e-04 Identities = 21/71 (29%), Positives = 43/71 (60%), Gaps = 5/71 (7%) Frame = +1 Query: 181 QFSEQRILGTGAFGIVYKGI-MPDGQ----IITVKKLAENSPIAREKAFANEVQNIMALH 345 +F + ++LG+GAFG +YKG+ +P+G+ + +K+L E + K +E + ++ Sbjct: 131 EFKKVKVLGSGAFGTIYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVD 190 Query: 346 HENVVKLVGYC 378 + +V +L+G C Sbjct: 191 NPHVCRLLGIC 201
>YL673_MIMIV (Q5UNT1) Putative serine/threonine-protein kinase L673 (EC| 2.7.11.1) Length = 545 Score = 42.7 bits (99), Expect = 6e-04 Identities = 31/112 (27%), Positives = 53/112 (47%), Gaps = 1/112 (0%) Frame = +1 Query: 160 FVKTITDQFSEQRILGTGAFGIVYKGIMPDGQIITVKKLAENSPIAREKAFANEVQNIMA 339 + K + Q LG+G +G VYK D Q I +KK+ S + EV N+M Sbjct: 256 YSKKTVKKIDFQNKLGSGTYGSVYKITYDDNQ-IAMKKIRNKSTFVIDSNMIREVNNLMI 314 Query: 340 LH-HENVVKLVGYCHEGQKKVVQNNGRYIVADIVESLLCHEYVPKGSLQKNL 492 L H N++ + GY + + YI D++++ L Y+ K ++ ++L Sbjct: 315 LSGHPNIINIEGYYYWDLTSTM-----YIGLDLMDTSLA-IYLTKNNISESL 360
>E2AK4_HUMAN (Q9P2K8) Eukaryotic translation initiation factor 2-alpha kinase 4| (EC 2.7.11.1) (GCN2-like protein) Length = 1649 Score = 42.7 bits (99), Expect = 6e-04 Identities = 35/111 (31%), Positives = 50/111 (45%), Gaps = 10/111 (9%) Frame = +1 Query: 61 SPQXLVQPSAMSTSAGGGQPSVLSTLPKN-LPLDFVKTITD--------QFSEQRILGTG 213 +PQ + S GGQ V + +P N LP + T +F E ++LG G Sbjct: 540 NPQPKMPLVEQSPEDSGGQDYVETVIPSNRLPSAAFFSETQRQFSRYFIEFEELQLLGKG 599 Query: 214 AFGIVYKGIMP-DGQIITVKKLAENSPIAREKAFANEVQNIMALHHENVVK 363 AFG V K DG VK++ N + + EV + LHHEN+V+ Sbjct: 600 AFGAVIKVQNKLDGCCYAVKRIPINPASRQFRRIKGEVTLLSRLHHENIVR 650
>AURKC_HUMAN (Q9UQB9) Serine/threonine-protein kinase 13 (EC 2.7.11.1)| (Aurora/Ipl1/Eg2 protein 2) (Aurora/Ipl1-related kinase 3) (Aurora-C) Length = 309 Score = 42.4 bits (98), Expect = 8e-04 Identities = 38/148 (25%), Positives = 59/148 (39%), Gaps = 3/148 (2%) Frame = +1 Query: 58 SSPQXLVQPSAMSTSAGGGQPSVLSTLPKNLPLDFVKTITDQFSEQRILGTGAFGIVYKG 237 SSP+ +VQ + AG + T + + D F R LG G FG VY Sbjct: 2 SSPRAVVQ-LGKAQPAGEELATANQTAQQPSSPAMRRLTVDDFEIGRPLGKGKFGNVYLA 60 Query: 238 IMPDGQIITVKKLAENSPIARE---KAFANEVQNIMALHHENVVKLVGYCHEGQKKVVQN 408 + + I K+ S I +E E++ L H N+++L Y H+ ++ Sbjct: 61 RLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQHPNILRLYNYFHDARRV---- 116 Query: 409 NGRYIVADIVESLLCHEYVPKGSLQKNL 492 Y++ EY P+G L K L Sbjct: 117 ---YLIL---------EYAPRGELYKEL 132
>TXK_HUMAN (P42681) Tyrosine-protein kinase TXK (EC 2.7.10.2)| Length = 527 Score = 42.4 bits (98), Expect = 8e-04 Identities = 30/99 (30%), Positives = 49/99 (49%), Gaps = 2/99 (2%) Frame = +1 Query: 202 LGTGAFGIVYKGIMPDGQIITVKKLAENSPIAREKAFANEVQNIMALHHENVVKLVGYCH 381 +G+G FG+V+ G + +K + E S E+ F E + +M L H +V+L G C Sbjct: 277 IGSGQFGVVHLGEWRSHIQVAIKAINEGS--MSEEDFIEEAKVMMKLSHSKLVQLYGVC- 333 Query: 382 EGQKKVVQNNGRYIVADIVES--LLCHEYVPKGSLQKNL 492 +Q YIV + +E+ LL + KG L+K + Sbjct: 334 ------IQRKPLYIVTEFMENGCLLNYLRENKGKLRKEM 366
>E2AK4_MOUSE (Q9QZ05) Eukaryotic translation initiation factor 2-alpha kinase 4| (EC 2.7.11.1) (GCN2-like protein) (mGCN2) Length = 1648 Score = 42.4 bits (98), Expect = 8e-04 Identities = 36/111 (32%), Positives = 49/111 (44%), Gaps = 10/111 (9%) Frame = +1 Query: 61 SPQXLVQPSAMSTSAGGGQPSVLSTLPKN-LP-LDFVKTITDQFS-------EQRILGTG 213 +PQ + S GGQ + + +P N LP F QFS E ++LG G Sbjct: 539 NPQPKLPLVEQSPEDSGGQDYIETVIPSNQLPSAAFFSETQKQFSRYFIEFEELQLLGKG 598 Query: 214 AFGIVYKGIMP-DGQIITVKKLAENSPIAREKAFANEVQNIMALHHENVVK 363 AFG V K DG VK++ N + EV + LHHEN+V+ Sbjct: 599 AFGAVIKVQNKLDGCCYAVKRIPINPASRHFRRIKGEVTLLSRLHHENIVR 649
>ROS_HUMAN (P08922) Proto-oncogene tyrosine-protein kinase ROS precursor (EC| 2.7.10.1) (c-ros-1) Length = 2347 Score = 42.0 bits (97), Expect = 0.001 Identities = 27/88 (30%), Positives = 45/88 (51%), Gaps = 7/88 (7%) Frame = +1 Query: 199 ILGTGAFGIVYKGIMPD------GQI-ITVKKLAENSPIAREKAFANEVQNIMALHHENV 357 +LG+GAFG VY+G D G+I + VK L + S + F E + +H N+ Sbjct: 1950 LLGSGAFGEVYEGTAVDILGVGSGEIKVAVKTLKKGSTDQEKIEFLKEAHLMSKFNHPNI 2009 Query: 358 VKLVGYCHEGQKKVVQNNGRYIVADIVE 441 +K +G C + N +YI+ +++E Sbjct: 2010 LKQLGVC-------LLNEPQYIILELME 2030
>PR2_DROME (Q9I7F7) Tyrosine-protein kinase PR2 (EC 2.7.10.2)| Length = 1337 Score = 42.0 bits (97), Expect = 0.001 Identities = 27/99 (27%), Positives = 45/99 (45%), Gaps = 3/99 (3%) Frame = +1 Query: 85 SAMSTSAGGGQPSVLSTLPKNLPLDFVKTITDQFSEQRILGTGAFGIVYKGIMPDGQ--- 255 S+++ G PS + +P D + S + LGTG FGIV +G+ +G Sbjct: 107 SSLAAKNGASSPSKVPNNKHIIPADSI-------SVNKQLGTGEFGIVQQGVWSNGNERI 159 Query: 256 IITVKKLAENSPIAREKAFANEVQNIMALHHENVVKLVG 372 + +K L + F E + ++ HEN+V+L G Sbjct: 160 QVAIKCLCRERMQSNPMEFLKEAAIMHSIEHENIVRLYG 198
>ERBB2_CANFA (O18735) Receptor tyrosine-protein kinase erbB-2 precursor (EC| 2.7.10.1) (p185erbB2) (C-erbB-2) Length = 1259 Score = 41.6 bits (96), Expect = 0.001 Identities = 24/66 (36%), Positives = 37/66 (56%), Gaps = 5/66 (7%) Frame = +1 Query: 196 RILGTGAFGIVYKGI-MPDGQ----IITVKKLAENSPIAREKAFANEVQNIMALHHENVV 360 ++LG+GAFG VYKGI +PDG+ + +K L EN+ K +E + + V Sbjct: 723 KVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSPYVS 782 Query: 361 KLVGYC 378 +L+G C Sbjct: 783 RLLGIC 788
>ERBB2_RAT (P06494) Receptor tyrosine-protein kinase erbB-2 precursor (EC| 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Epidermal growth factor receptor-related protein) Length = 1257 Score = 41.6 bits (96), Expect = 0.001 Identities = 24/66 (36%), Positives = 37/66 (56%), Gaps = 5/66 (7%) Frame = +1 Query: 196 RILGTGAFGIVYKGI-MPDGQ----IITVKKLAENSPIAREKAFANEVQNIMALHHENVV 360 ++LG+GAFG VYKGI +PDG+ + +K L EN+ K +E + + V Sbjct: 726 KVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSPYVS 785 Query: 361 KLVGYC 378 +L+G C Sbjct: 786 RLLGIC 791
>MOS_ATHSQ (Q8AX02) Serine/threonine-protein kinase mos (EC 2.7.11.1) (Oocyte| maturation factor mos) (Fragment) Length = 194 Score = 41.6 bits (96), Expect = 0.001 Identities = 36/106 (33%), Positives = 53/106 (50%), Gaps = 2/106 (1%) Frame = +1 Query: 58 SSPQXLVQPSAMSTSAGGGQPSVLSTLPKNLPLDFVKTITDQFSEQRILGTGAFGIVYKG 237 SSP LV P+ G G + + LP +L + DQ +LG+G FG VYK Sbjct: 9 SSP--LVCPAKGENFFGVGNVARIRRLPPHLA--WCSIDWDQLCLLHLLGSGGFGSVYKA 64 Query: 238 IMPDGQIITVKKL--AENSPIAREKAFANEVQNIMALHHENVVKLV 369 I G + VKK+ + +A ++F E+ N+ L H NVV++V Sbjct: 65 IY-HGATVAVKKVKRCSKNHLASRQSFWAEL-NVARLGHNNVVRIV 108
>CC2H3_TRYBB (P54666) Cell division control protein 2 homolog 3 (EC 2.7.11.22)| Length = 311 Score = 41.6 bits (96), Expect = 0.001 Identities = 30/119 (25%), Positives = 56/119 (47%), Gaps = 24/119 (20%) Frame = +1 Query: 178 DQFSEQRILGTGAFGIVYKGI-MPDGQIITVKKL-AENSPIAREKAFANEVQNIMALHHE 351 D+++ ILG G +G+VY+ + GQI+ +KK+ + + + EV + +HH Sbjct: 21 DRYNRMDILGEGTYGVVYRAVDRATGQIVALKKVRLDRTDEGIPQTALREVSILQEIHHP 80 Query: 352 NVVKLVG-YCHEGQ------------KKVVQNNG--------RYIVADIVESL-LCHEY 462 N+V L+ C +G+ KK ++ G + I+ ++E L CH + Sbjct: 81 NIVNLLDVICADGKLYLIFEYVDHDLKKALEKRGGAFTGTTLKKIIYQLLEGLSFCHRH 139
>JAK1_HUMAN (P23458) Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1)| (JAK-1) Length = 1142 Score = 41.6 bits (96), Expect = 0.001 Identities = 39/131 (29%), Positives = 58/131 (44%), Gaps = 6/131 (4%) Frame = +1 Query: 118 PSVLSTLPKNLPLDFVKTITDQFSEQRI--LGTGAFGIV----YKGIMPDGQIITVKKLA 279 P ++S KN P + T ++ +RI LG G FG V Y G+ + VK L Sbjct: 841 PDIVSR-KKNQPTEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEDNTGEQVAVKSLK 899 Query: 280 ENSPIAREKAFANEVQNIMALHHENVVKLVGYCHEGQKKVVQNNGRYIVADIVESLLCHE 459 S E++ + L+HEN+VK G C E NG ++ + + S E Sbjct: 900 PESGGNHIADLKKEIEILRNLYHENIVKYKGICTED-----GGNGIKLIMEFLPSGSLKE 954 Query: 460 YVPKGSLQKNL 492 Y+PK + NL Sbjct: 955 YLPKNKNKINL 965
>IRAK2_HUMAN (O43187) Interleukin-1 receptor-associated kinase-like 2 (IRAK-2)| Length = 590 Score = 41.6 bits (96), Expect = 0.001 Identities = 25/71 (35%), Positives = 39/71 (54%), Gaps = 3/71 (4%) Frame = +1 Query: 175 TDQFSEQRILGTGAFGIVYKGIMPDGQIITVKKLAE---NSPIAREKAFANEVQNIMALH 345 TD F++ R + G F VY+G G+ KKL E +SP + E+ F E+Q + Sbjct: 207 TDDFNQNRKISQGTFADVYRGHR-HGKPFVFKKLRETACSSPGSIERFFQAELQICLRCC 265 Query: 346 HENVVKLVGYC 378 H NV+ ++G+C Sbjct: 266 HPNVLPVLGFC 276
>ERBB2_MOUSE (P70424) Receptor tyrosine-protein kinase erbB-2 precursor (EC| 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) Length = 1256 Score = 41.6 bits (96), Expect = 0.001 Identities = 24/66 (36%), Positives = 37/66 (56%), Gaps = 5/66 (7%) Frame = +1 Query: 196 RILGTGAFGIVYKGI-MPDGQ----IITVKKLAENSPIAREKAFANEVQNIMALHHENVV 360 ++LG+GAFG VYKGI +PDG+ + +K L EN+ K +E + + V Sbjct: 725 KVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSPYVS 784 Query: 361 KLVGYC 378 +L+G C Sbjct: 785 RLLGIC 790
>ERBB2_HUMAN (P04626) Receptor tyrosine-protein kinase erbB-2 precursor (EC| 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Tyrosine kinase-type cell surface receptor HER2) (MLN 19) Length = 1255 Score = 41.6 bits (96), Expect = 0.001 Identities = 24/66 (36%), Positives = 37/66 (56%), Gaps = 5/66 (7%) Frame = +1 Query: 196 RILGTGAFGIVYKGI-MPDGQ----IITVKKLAENSPIAREKAFANEVQNIMALHHENVV 360 ++LG+GAFG VYKGI +PDG+ + +K L EN+ K +E + + V Sbjct: 724 KVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSPYVS 783 Query: 361 KLVGYC 378 +L+G C Sbjct: 784 RLLGIC 789
>HTK16_HYDAT (P53356) Tyrosine-protein kinase HTK16 (EC 2.7.10.2)| Length = 757 Score = 41.2 bits (95), Expect = 0.002 Identities = 44/159 (27%), Positives = 72/159 (45%), Gaps = 4/159 (2%) Frame = +1 Query: 64 PQXLVQPSAMSTSAGGGQPSVLSTLPKNLPLDFVKTITDQFSEQRILGTGAFGIVYKGIM 243 P+ +V + + S GQ T+ N + + + F ++ LG G FG V KGI Sbjct: 447 PRPVVNHTEVPNSVNVGQKGD-QTMKNNAQQNIILKESISFGKE--LGVGEFGSVIKGIW 503 Query: 244 --PDGQIITV--KKLAENSPIAREKAFANEVQNIMALHHENVVKLVGYCHEGQKKVVQNN 411 P G+ I V K L ++ + EK F E + L+H +V L+G C +VQ Sbjct: 504 LSPGGKEINVAMKTLHKDKMVQGEKEFLREALVMSQLNHPCIVSLLGVCLGPPMILVQ-- 561 Query: 412 GRYIVADIVESLLCHEYVPKGSLQKNLFEVDTKMDWSTR 528 ++VE +Y+ Q + EVD K+ W+++ Sbjct: 562 ------ELVEMGALLDYLM--DYQPEIQEVDLKL-WASQ 591
>NTRK1_HUMAN (P04629) High affinity nerve growth factor receptor precursor (EC| 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1 transforming tyrosine kinase protein) (p140-TrkA) (Trk-A) Length = 796 Score = 41.2 bits (95), Expect = 0.002 Identities = 25/69 (36%), Positives = 38/69 (55%), Gaps = 6/69 (8%) Frame = +1 Query: 202 LGTGAFGIVY----KGIMP--DGQIITVKKLAENSPIAREKAFANEVQNIMALHHENVVK 363 LG GAFG V+ ++P D ++ VK L E S AR+ F E + + L H+++V+ Sbjct: 516 LGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQD-FQREAELLTMLQHQHIVR 574 Query: 364 LVGYCHEGQ 390 G C EG+ Sbjct: 575 FFGVCTEGR 583
>FES_HUMAN (P07332) Proto-oncogene tyrosine-protein kinase Fes/Fps (EC| 2.7.10.2) (C-Fes) Length = 822 Score = 41.2 bits (95), Expect = 0.002 Identities = 24/81 (29%), Positives = 38/81 (46%), Gaps = 1/81 (1%) Frame = +1 Query: 202 LGTGAFGIVYKG-IMPDGQIITVKKLAENSPIAREKAFANEVQNIMALHHENVVKLVGYC 378 +G G FG V+ G + D ++ VK E P + F E + + H N+V+L+G C Sbjct: 567 IGRGNFGEVFSGRLRADNTLVAVKSCRETLPPDLKAKFLQEARILKQYSHPNIVRLIGVC 626 Query: 379 HEGQKKVVQNNGRYIVADIVE 441 Q YIV ++V+ Sbjct: 627 -------TQKQPIYIVMELVQ 640
>FES_FSVST (P00543) Tyrosine-protein kinase transforming protein Fes (EC| 2.7.10.2) Length = 477 Score = 40.8 bits (94), Expect = 0.002 Identities = 24/81 (29%), Positives = 38/81 (46%), Gaps = 1/81 (1%) Frame = +1 Query: 202 LGTGAFGIVYKG-IMPDGQIITVKKLAENSPIAREKAFANEVQNIMALHHENVVKLVGYC 378 +G G FG V+ G + D ++ VK E P + F E + + H N+V+L+G C Sbjct: 222 IGRGNFGEVFSGRLRADNTLVAVKSCRETLPPDIKAKFLQEAKILKQYSHPNIVRLIGVC 281 Query: 379 HEGQKKVVQNNGRYIVADIVE 441 Q YIV ++V+ Sbjct: 282 -------TQKQPIYIVMELVQ 295
>FES_FELCA (P14238) Proto-oncogene tyrosine-protein kinase FES/FPS (EC| 2.7.10.2) (C-FES) Length = 820 Score = 40.8 bits (94), Expect = 0.002 Identities = 24/81 (29%), Positives = 38/81 (46%), Gaps = 1/81 (1%) Frame = +1 Query: 202 LGTGAFGIVYKG-IMPDGQIITVKKLAENSPIAREKAFANEVQNIMALHHENVVKLVGYC 378 +G G FG V+ G + D ++ VK E P + F E + + H N+V+L+G C Sbjct: 565 IGRGNFGEVFSGRLRADNTLVAVKSCRETLPPDIKAKFLQEAKILKQYSHPNIVRLIGVC 624 Query: 379 HEGQKKVVQNNGRYIVADIVE 441 Q YIV ++V+ Sbjct: 625 -------TQKQPIYIVMELVQ 638
>JNK1_CAEEL (Q8WQG9) Stress-activated protein kinase jnk-1 (EC 2.7.11.24)| Length = 463 Score = 40.8 bits (94), Expect = 0.002 Identities = 24/96 (25%), Positives = 52/96 (54%), Gaps = 2/96 (2%) Frame = +1 Query: 172 ITDQFSEQRILGTGAFGIVYKGI-MPDGQIITVKKLAEN-SPIAREKAFANEVQNIMALH 345 + ++ R++G+GA GIV + + +KKL+ + K E++ + ++ Sbjct: 115 VLKRYQNLRLIGSGAQGIVCSAFDTVRNEQVAIKKLSRPFQNVTHAKRAYRELKLMSLVN 174 Query: 346 HENVVKLVGYCHEGQKKVVQNNGRYIVADIVESLLC 453 H+N++ ++ C QKK+ + N YIV +++++ LC Sbjct: 175 HKNIIGILN-CFTPQKKLDEFNDLYIVMELMDANLC 209
>SGG_DROME (P18431) Protein kinase shaggy (EC 2.7.11.1) (Protein zeste-white| 3) Length = 1067 Score = 40.8 bits (94), Expect = 0.002 Identities = 20/73 (27%), Positives = 46/73 (63%), Gaps = 2/73 (2%) Frame = +1 Query: 184 FSEQRILGTGAFGIVYKGIMPD-GQIITVKKLAENSPIAREKAFAN-EVQNIMALHHENV 357 +++ +++G G+FG+V++ + D G+++ +KK + +++ F N E+Q + L H N+ Sbjct: 607 YTDTKVIGNGSFGVVFQAKLCDTGELVAIKK------VLQDRRFKNRELQIMRKLEHCNI 660 Query: 358 VKLVGYCHEGQKK 396 VKL+ + + +K Sbjct: 661 VKLLYFFYSSGEK 673
>FES_FSVGA (P00542) Tyrosine-protein kinase transforming protein Fes (EC| 2.7.10.2) Length = 609 Score = 40.8 bits (94), Expect = 0.002 Identities = 24/81 (29%), Positives = 38/81 (46%), Gaps = 1/81 (1%) Frame = +1 Query: 202 LGTGAFGIVYKG-IMPDGQIITVKKLAENSPIAREKAFANEVQNIMALHHENVVKLVGYC 378 +G G FG V+ G + D ++ VK E P + F E + + H N+V+L+G C Sbjct: 354 IGRGNFGEVFSGRLRADNTLVAVKSCRETLPPDIKAKFLQEAKILKQYSHPNIVRLIGVC 413 Query: 379 HEGQKKVVQNNGRYIVADIVE 441 Q YIV ++V+ Sbjct: 414 -------TQKQPIYIVMELVQ 427
>FPS_AVISP (P00541) Tyrosine-protein kinase transforming protein Fps (EC| 2.7.10.2) Length = 533 Score = 40.4 bits (93), Expect = 0.003 Identities = 24/81 (29%), Positives = 38/81 (46%), Gaps = 1/81 (1%) Frame = +1 Query: 202 LGTGAFGIVYKG-IMPDGQIITVKKLAENSPIAREKAFANEVQNIMALHHENVVKLVGYC 378 +G G FG V+ G + D + VK E P + F E + + +H N+V+L+G C Sbjct: 278 IGRGNFGEVFSGRLRADNTPVAVKSCRETLPPELKAKFLQEARILKQYNHPNIVRLIGVC 337 Query: 379 HEGQKKVVQNNGRYIVADIVE 441 Q YIV ++V+ Sbjct: 338 -------TQKQPIYIVMELVQ 351
>FPS_FUJSV (P00530) Tyrosine-protein kinase transforming protein FPS (EC| 2.7.10.2) Length = 873 Score = 40.4 bits (93), Expect = 0.003 Identities = 24/81 (29%), Positives = 38/81 (46%), Gaps = 1/81 (1%) Frame = +1 Query: 202 LGTGAFGIVYKG-IMPDGQIITVKKLAENSPIAREKAFANEVQNIMALHHENVVKLVGYC 378 +G G FG V+ G + D + VK E P + F E + + +H N+V+L+G C Sbjct: 618 IGRGNFGEVFSGRLRADNTPVAVKSCRETLPPELKAKFLQEARILKQCNHPNIVRLIGVC 677 Query: 379 HEGQKKVVQNNGRYIVADIVE 441 Q YIV ++V+ Sbjct: 678 -------TQKQPIYIVMELVQ 691
>BYR2_SCHPO (P28829) Protein kinase byr2 (EC 2.7.11.25) (Protein kinase ste8)| (MAPK kinase kinase) (MAPKKK) Length = 659 Score = 40.4 bits (93), Expect = 0.003 Identities = 37/129 (28%), Positives = 67/129 (51%), Gaps = 11/129 (8%) Frame = +1 Query: 19 TARXNHPQCWXFS--SSPQXLVQPSAMSTSAGGGQPSVLSTLPKNLPLDFVKTITDQFSE 192 +A NH Q FS SSP + QPS +S ++ + + +TL ++ +K I Sbjct: 345 SAHGNH-QVLSFSPGSSPSFIEQPSPISPTSTTSEDT--NTLEEDTDDQSIKWIRGA--- 398 Query: 193 QRILGTGAFGIVYKGI-MPDGQIITVKKLAENSPIAREK--------AFANEVQNIMALH 345 ++G+G+FG VY G+ G+++ VK++ +S ++ K A A E+ + L Sbjct: 399 --LIGSGSFGQVYLGMNASSGELMAVKQVILDS-VSESKDRHAKLLDALAGEIALLQELS 455 Query: 346 HENVVKLVG 372 HE++V+ +G Sbjct: 456 HEHIVQYLG 464
>ERBB3_PONPY (Q5RB22) Receptor tyrosine-protein kinase erbB-3 precursor (EC| 2.7.10.1) Length = 1342 Score = 40.4 bits (93), Expect = 0.003 Identities = 30/109 (27%), Positives = 58/109 (53%), Gaps = 5/109 (4%) Frame = +1 Query: 181 QFSEQRILGTGAFGIVYKGI-MPDGQII----TVKKLAENSPIAREKAFANEVQNIMALH 345 + + ++LG+G FG V+KG+ +P+G+ I +K + + S +A + + I +L Sbjct: 708 ELKKLKVLGSGVFGTVHKGVWIPEGESIKIPVCIKVIEDKSGRQSFQAVTDHMLAIGSLD 767 Query: 346 HENVVKLVGYCHEGQKKVVQNNGRYIVADIVESLLCHEYVPKGSLQKNL 492 H ++V+L+G C ++V +Y+ + SLL H +G+L L Sbjct: 768 HAHIVRLLGLCPGSSLQLVT---QYLP---LGSLLDHVRQHRGALGPQL 810
>RON_MOUSE (Q62190) Macrophage-stimulating protein receptor precursor (EC| 2.7.10.1) (MSP receptor) (p185-Ron) (Stem cell-derived tyrosine kinase) (CDw136 antigen) [Contains: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating prote Length = 1378 Score = 40.4 bits (93), Expect = 0.003 Identities = 25/79 (31%), Positives = 39/79 (49%), Gaps = 4/79 (5%) Frame = +1 Query: 148 LPLDFVKTITDQFSEQRILGTGAFGIVYKGIMPDGQI----ITVKKLAENSPIAREKAFA 315 +P + V TDQ ++G G FG+VY G DG +K L+ + + +AF Sbjct: 1052 IPHEQVVIHTDQ-----VIGKGHFGVVYHGEYTDGAQNQTHCAIKSLSRITEVQEVEAFL 1106 Query: 316 NEVQNIMALHHENVVKLVG 372 E + LHH N++ L+G Sbjct: 1107 REGLLMRGLHHPNILALIG 1125
>M3K7_MOUSE (Q62073) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1) Length = 579 Score = 40.4 bits (93), Expect = 0.003 Identities = 25/98 (25%), Positives = 50/98 (51%) Frame = +1 Query: 85 SAMSTSAGGGQPSVLSTLPKNLPLDFVKTITDQFSEQRILGTGAFGIVYKGIMPDGQIIT 264 ++ ++S+ S + P + L+F + + + ++G GAFG+V K + + Sbjct: 4 ASAASSSSSSSASEMIEAPSQV-LNFEEIDYKEIEVEEVVGRGAFGVVCKAKWR-AKDVA 61 Query: 265 VKKLAENSPIAREKAFANEVQNIMALHHENVVKLVGYC 378 +K++ S KAF E++ + ++H N+VKL G C Sbjct: 62 IKQIESES---ERKAFIVELRQLSRVNHPNIVKLYGAC 96
>MOS_SIBNE (Q8AX00) Serine/threonine-protein kinase mos (EC 2.7.11.1) (Oocyte| maturation factor mos) (Fragment) Length = 193 Score = 40.0 bits (92), Expect = 0.004 Identities = 35/106 (33%), Positives = 48/106 (45%), Gaps = 2/106 (1%) Frame = +1 Query: 58 SSPQXLVQPSAMSTSAGGGQPSVLSTLPKNLPLDFVKTITDQFSEQRILGTGAFGIVYKG 237 SSP LV P+ G G S + LP L + DQ +LG+G FG VYK Sbjct: 9 SSP--LVCPAKGEKFFGVGSASRIRQLPPRLA--WCSIDWDQLCLLHLLGSGGFGSVYKA 64 Query: 238 IMPDGQIIT--VKKLAENSPIAREKAFANEVQNIMALHHENVVKLV 369 + VKK ++N +R+ +A N+ L H NVV +V Sbjct: 65 TYHGATVAVKQVKKCSKNHLASRQSFWAE--LNVACLDHNNVVHIV 108
>ZYG1_CAEBR (Q621J7) Probable serine/threonine-protein kinase zyg-1 (EC| 2.7.11.1) (Zygote defective protein 1) Length = 709 Score = 40.0 bits (92), Expect = 0.004 Identities = 27/105 (25%), Positives = 47/105 (44%), Gaps = 1/105 (0%) Frame = +1 Query: 169 TITDQFSEQRILGTGAFGIVYKGIMPDGQIITVKKLAENSPIAREKAFANEVQNIMALHH 348 T F + +G G FG+VY +G+ + +KK+ + R K E++ + L H Sbjct: 8 TKLSSFQNLQQIGQGGFGVVYSAQRENGEKVAIKKIGNAASQTRIK---EEIKTMKLLRH 64 Query: 349 ENVVKLVGYCHEGQKKVVQNNGRYIVADIVESLLCHEYV-PKGSL 480 N+V+ + +N Y+V ++ E +YV KG L Sbjct: 65 RNIVQF-------YETFFENGETYLVMELCEGGSLMDYVKQKGPL 102
>ROR2_DROME (Q9V6K3) Tyrosine-protein kinase transmembrane receptor Ror2| precursor (EC 2.7.10.1) (Neurospecific receptor tyrosine kinase) Length = 724 Score = 40.0 bits (92), Expect = 0.004 Identities = 23/71 (32%), Positives = 39/71 (54%), Gaps = 6/71 (8%) Frame = +1 Query: 196 RILGTGAFGIVYK----GIMPDGQ--IITVKKLAENSPIAREKAFANEVQNIMALHHENV 357 R LG GAFG V++ G++PD + ++ VK L +++ + F E + H N+ Sbjct: 445 RSLGQGAFGRVFQARAPGLVPDQEDLLVAVKMLKDDASDQMQMDFEREACLLAEFDHPNI 504 Query: 358 VKLVGYCHEGQ 390 V+L+G C G+ Sbjct: 505 VRLLGVCALGR 515
>MIPR_LYMST (Q25410) Putative molluscan insulin-related peptide(s) receptor| precursor (EC 2.7.10.1) [Contains: Putative molluscan insulin-related peptide(s) receptor alpha chain; Putative molluscan insulin-related peptide(s) receptor beta chain] Length = 1607 Score = 40.0 bits (92), Expect = 0.004 Identities = 23/74 (31%), Positives = 39/74 (52%), Gaps = 7/74 (9%) Frame = +1 Query: 202 LGTGAFGIVYKGIM------PDGQI-ITVKKLAENSPIAREKAFANEVQNIMALHHENVV 360 LG G+FG+VY+G+ P+ +I + VK + + + + + F E + H +VV Sbjct: 1043 LGQGSFGMVYEGVAKGIRDDPNEEIPVAVKTVNDRASFSDRREFLKEATTMKEFHCHHVV 1102 Query: 361 KLVGYCHEGQKKVV 402 KL+G GQ +V Sbjct: 1103 KLLGVVSTGQPALV 1116
>GCN2_SCHPO (Q9HGN1) Serine/threonine-protein kinase gcn2 (EC 2.7.11.1)| Length = 1576 Score = 40.0 bits (92), Expect = 0.004 Identities = 30/89 (33%), Positives = 37/89 (41%), Gaps = 1/89 (1%) Frame = +1 Query: 100 SAGGGQPSVLSTLPKNLPLDFVKTITDQFSEQRILGTGAFGIVYK-GIMPDGQIITVKKL 276 S GG Q ++ L + V F E LG G FG V K DG+ VKKL Sbjct: 532 SYGGQQDGIIDLLYRKS----VSRYETDFEELEFLGRGGFGEVVKVKNRIDGRFYAVKKL 587 Query: 277 AENSPIAREKAFANEVQNIMALHHENVVK 363 S EV + LHHE+VV+ Sbjct: 588 VLLSDDKENSRILREVMTLSRLHHEHVVR 616
>ILPR_BRALA (O02466) Insulin-like peptide receptor precursor (EC 2.7.10.1) (ILP| receptor) [Contains: Insulin-like peptide receptor alpha chain; Insulin-like peptide receptor beta chain] Length = 1363 Score = 40.0 bits (92), Expect = 0.004 Identities = 25/75 (33%), Positives = 42/75 (56%), Gaps = 6/75 (8%) Frame = +1 Query: 196 RILGTGAFGIVYKG----IMPDGQIITV--KKLAENSPIAREKAFANEVQNIMALHHENV 357 R LG G+FG+VY+G ++ D +++V K + E++ I F NE + + +V Sbjct: 998 RELGQGSFGMVYEGEAKDVVKDEPMVSVAVKTVNESASIRERIEFLNEASVMKTFNCHHV 1057 Query: 358 VKLVGYCHEGQKKVV 402 VKL+G +GQ +V Sbjct: 1058 VKLMGVVSKGQPTLV 1072
>NTRK2_CHICK (Q91987) BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (Trk-B) Length = 818 Score = 40.0 bits (92), Expect = 0.004 Identities = 28/76 (36%), Positives = 40/76 (52%), Gaps = 6/76 (7%) Frame = +1 Query: 193 QRILGTGAFGIVYKG----IMP--DGQIITVKKLAENSPIAREKAFANEVQNIMALHHEN 354 +R LG GAFG V+ + P D ++ VK L + S AR K F E + + L HE+ Sbjct: 537 KRELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKDASDNAR-KDFHREAELLTNLQHEH 595 Query: 355 VVKLVGYCHEGQKKVV 402 +VK G C EG ++ Sbjct: 596 IVKFYGVCVEGDPLIM 611
>ERBB3_HUMAN (P21860) Receptor tyrosine-protein kinase erbB-3 precursor (EC| 2.7.10.1) (c-erbB3) (Tyrosine kinase-type cell surface receptor HER3) Length = 1342 Score = 40.0 bits (92), Expect = 0.004 Identities = 30/104 (28%), Positives = 56/104 (53%), Gaps = 5/104 (4%) Frame = +1 Query: 196 RILGTGAFGIVYKGI-MPDGQII----TVKKLAENSPIAREKAFANEVQNIMALHHENVV 360 ++LG+G FG V+KG+ +P+G+ I +K + + S +A + + I +L H ++V Sbjct: 713 KVLGSGVFGTVHKGVWIPEGESIKIPVCIKVIEDKSGRQSFQAVTDHMLAIGSLDHAHIV 772 Query: 361 KLVGYCHEGQKKVVQNNGRYIVADIVESLLCHEYVPKGSLQKNL 492 +L+G C ++V +Y+ + SLL H +G+L L Sbjct: 773 RLLGLCPGSSLQLVT---QYLP---LGSLLDHVRQHRGALGPQL 810
>CDKL2_MACFA (Q4R7T5) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| Length = 570 Score = 40.0 bits (92), Expect = 0.004 Identities = 31/116 (26%), Positives = 58/116 (50%), Gaps = 8/116 (6%) Frame = +1 Query: 178 DQFSEQRILGTGAFGIVYKGIMPD-GQIITVKKLAENSPIAREKAFA-NEVQNIMALHHE 351 +++ ++G G++G+V K D G+I+ +KK E+ K A E++ + L HE Sbjct: 2 EKYENLGLVGEGSYGMVVKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHE 61 Query: 352 NVVKLVGYCHEGQKKVVQNNGRYIVADIVESLLCH--EYVPKG----SLQKNLFEV 501 N+V L+ C + ++ Y+V + V+ + E P G +QK LF++ Sbjct: 62 NLVNLLEVCKKKKR-------WYLVFEFVDHTILDDLELFPNGLDYQVVQKYLFQI 110
>NTRK2_HUMAN (Q16620) BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB) (Trk-B) Length = 822 Score = 40.0 bits (92), Expect = 0.004 Identities = 28/76 (36%), Positives = 40/76 (52%), Gaps = 6/76 (7%) Frame = +1 Query: 193 QRILGTGAFGIVYKG----IMP--DGQIITVKKLAENSPIAREKAFANEVQNIMALHHEN 354 +R LG GAFG V+ + P D ++ VK L + S AR K F E + + L HE+ Sbjct: 541 KRELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKDASDNAR-KDFHREAELLTNLQHEH 599 Query: 355 VVKLVGYCHEGQKKVV 402 +VK G C EG ++ Sbjct: 600 IVKFYGVCVEGDPLIM 615
>NTRK2_RAT (Q63604) BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB/GP95-TrkB) (Trk-B) Length = 821 Score = 40.0 bits (92), Expect = 0.004 Identities = 28/76 (36%), Positives = 40/76 (52%), Gaps = 6/76 (7%) Frame = +1 Query: 193 QRILGTGAFGIVYKG----IMP--DGQIITVKKLAENSPIAREKAFANEVQNIMALHHEN 354 +R LG GAFG V+ + P D ++ VK L + S AR K F E + + L HE+ Sbjct: 540 KRELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKDASDNAR-KDFHREAELLTNLQHEH 598 Query: 355 VVKLVGYCHEGQKKVV 402 +VK G C EG ++ Sbjct: 599 IVKFYGVCVEGDPLIM 614
>NTRK2_MOUSE (P15209) BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB/GP95-TrkB) (Trk-B) Length = 821 Score = 40.0 bits (92), Expect = 0.004 Identities = 28/76 (36%), Positives = 40/76 (52%), Gaps = 6/76 (7%) Frame = +1 Query: 193 QRILGTGAFGIVYKG----IMP--DGQIITVKKLAENSPIAREKAFANEVQNIMALHHEN 354 +R LG GAFG V+ + P D ++ VK L + S AR K F E + + L HE+ Sbjct: 540 KRELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKDASDNAR-KDFHREAELLTNLQHEH 598 Query: 355 VVKLVGYCHEGQKKVV 402 +VK G C EG ++ Sbjct: 599 IVKFYGVCVEGDPLIM 614
>CDKL2_PONPY (Q5R754) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| Length = 493 Score = 40.0 bits (92), Expect = 0.004 Identities = 31/116 (26%), Positives = 58/116 (50%), Gaps = 8/116 (6%) Frame = +1 Query: 178 DQFSEQRILGTGAFGIVYKGIMPD-GQIITVKKLAENSPIAREKAFA-NEVQNIMALHHE 351 +++ ++G G++G+V K D G+I+ +KK E+ K A E++ + L HE Sbjct: 2 EKYENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHE 61 Query: 352 NVVKLVGYCHEGQKKVVQNNGRYIVADIVESLLCH--EYVPKG----SLQKNLFEV 501 N+V L+ C + ++ Y+V + V+ + E P G +QK LF++ Sbjct: 62 NLVNLLEVCKKKKR-------WYLVFEFVDHTILDDLELFPNGLDYQVVQKYLFQI 110
>CDKL2_HUMAN (Q92772) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| (Serine/threonine-protein kinase KKIAMRE) (Protein kinase p56 KKIAMRE) Length = 493 Score = 40.0 bits (92), Expect = 0.004 Identities = 31/116 (26%), Positives = 58/116 (50%), Gaps = 8/116 (6%) Frame = +1 Query: 178 DQFSEQRILGTGAFGIVYKGIMPD-GQIITVKKLAENSPIAREKAFA-NEVQNIMALHHE 351 +++ ++G G++G+V K D G+I+ +KK E+ K A E++ + L HE Sbjct: 2 EKYENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHE 61 Query: 352 NVVKLVGYCHEGQKKVVQNNGRYIVADIVESLLCH--EYVPKG----SLQKNLFEV 501 N+V L+ C + ++ Y+V + V+ + E P G +QK LF++ Sbjct: 62 NLVNLLEVCKKKKR-------WYLVFEFVDHTILDDLELFPNGLDYQVVQKYLFQI 110
>FES_MOUSE (P16879) Proto-oncogene tyrosine-protein kinase Fes/Fps (EC| 2.7.10.2) (C-Fes) Length = 820 Score = 40.0 bits (92), Expect = 0.004 Identities = 24/81 (29%), Positives = 38/81 (46%), Gaps = 1/81 (1%) Frame = +1 Query: 202 LGTGAFGIVYKG-IMPDGQIITVKKLAENSPIAREKAFANEVQNIMALHHENVVKLVGYC 378 +G G FG V+ G + D + VK E P + F E + + +H N+V+L+G C Sbjct: 565 IGRGNFGEVFSGRLRADNTPVAVKSCRETLPPDLKAKFLQEARILKQYNHPNIVRLIGVC 624 Query: 379 HEGQKKVVQNNGRYIVADIVE 441 Q YIV ++V+ Sbjct: 625 -------TQKQPIYIVMELVQ 638
>CDKL2_RABIT (Q9TTK0) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| (Serine/threonine-protein kinase KKIAMRE) Length = 566 Score = 40.0 bits (92), Expect = 0.004 Identities = 31/116 (26%), Positives = 58/116 (50%), Gaps = 8/116 (6%) Frame = +1 Query: 178 DQFSEQRILGTGAFGIVYKGIMPD-GQIITVKKLAENSPIAREKAFA-NEVQNIMALHHE 351 +++ ++G G++G+V K D G+I+ +KK E+ K A E++ + L HE Sbjct: 2 EKYENLGLVGEGSYGMVMKCRNKDSGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHE 61 Query: 352 NVVKLVGYCHEGQKKVVQNNGRYIVADIVESLLCH--EYVPKG----SLQKNLFEV 501 N+V L+ C + ++ Y+V + V+ + E P G +QK LF++ Sbjct: 62 NLVNLLEVCKKKKR-------WYLVFEFVDHTILDDLELFPNGLDDQVVQKYLFQI 110
>INSR_DROME (P09208) Insulin-like receptor precursor (EC 2.7.10.1) (DIR) (DInr)| (dIRH) [Contains: Insulin-like receptor alpha subunit; Insulin-like receptor beta 1 subunit; Insulin-like receptor beta 2 subunit] Length = 2144 Score = 39.7 bits (91), Expect = 0.005 Identities = 24/73 (32%), Positives = 39/73 (53%), Gaps = 6/73 (8%) Frame = +1 Query: 202 LGTGAFGIVYKGIM----PDG--QIITVKKLAENSPIAREKAFANEVQNIMALHHENVVK 363 LG G+FG+VY+GI+ P+G + +K + EN+ F +E + +VV+ Sbjct: 1377 LGQGSFGMVYEGILKSFPPNGVDRECAIKTVNENATDRERTNFLSEASVMKEFDTYHVVR 1436 Query: 364 LVGYCHEGQKKVV 402 L+G C GQ +V Sbjct: 1437 LLGVCSRGQPALV 1449
>ERBB3_RAT (Q62799) Receptor tyrosine-protein kinase erbB-3 precursor (EC| 2.7.10.1) (c-erbB3) Length = 1339 Score = 39.7 bits (91), Expect = 0.005 Identities = 21/66 (31%), Positives = 40/66 (60%), Gaps = 5/66 (7%) Frame = +1 Query: 196 RILGTGAFGIVYKGI-MPDGQII----TVKKLAENSPIAREKAFANEVQNIMALHHENVV 360 ++LG+G FG V+KGI +P+G+ I +K + + S +A + + + +L H ++V Sbjct: 711 KVLGSGVFGTVHKGIWIPEGESIKIPVCIKVIEDKSGRQSFQAVTDHMLAVGSLDHAHIV 770 Query: 361 KLVGYC 378 +L+G C Sbjct: 771 RLLGLC 776
>ERBB3_MOUSE (Q61526) Receptor tyrosine-protein kinase erbB-3 precursor (EC| 2.7.10.1) (c-erbB3) (Glial growth factor receptor) Length = 1339 Score = 39.7 bits (91), Expect = 0.005 Identities = 21/66 (31%), Positives = 40/66 (60%), Gaps = 5/66 (7%) Frame = +1 Query: 196 RILGTGAFGIVYKGI-MPDGQII----TVKKLAENSPIAREKAFANEVQNIMALHHENVV 360 ++LG+G FG V+KGI +P+G+ I +K + + S +A + + + +L H ++V Sbjct: 711 KVLGSGVFGTVHKGIWIPEGESIKIPVCIKVIEDKSGRQSFQAVTDHMLAVGSLDHAHIV 770 Query: 361 KLVGYC 378 +L+G C Sbjct: 771 RLLGLC 776
>NTRK3_CHICK (Q91044) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (Trk-C) Length = 827 Score = 39.7 bits (91), Expect = 0.005 Identities = 26/76 (34%), Positives = 40/76 (52%), Gaps = 6/76 (7%) Frame = +1 Query: 193 QRILGTGAFGIVYKG----IMP--DGQIITVKKLAENSPIAREKAFANEVQNIMALHHEN 354 +R LG GAFG V+ + P D ++ VK L + + AR K F E + + L HE+ Sbjct: 543 KRELGEGAFGKVFLAECYNLSPTNDKMLVAVKALKDPTLAAR-KDFQREAELLTNLQHEH 601 Query: 355 VVKLVGYCHEGQKKVV 402 +VK G C +G ++ Sbjct: 602 IVKFYGVCGDGDPLIM 617
>NTRK3_SAIBB (Q5IS82) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) Length = 825 Score = 39.7 bits (91), Expect = 0.005 Identities = 26/76 (34%), Positives = 40/76 (52%), Gaps = 6/76 (7%) Frame = +1 Query: 193 QRILGTGAFGIVYKG----IMP--DGQIITVKKLAENSPIAREKAFANEVQNIMALHHEN 354 +R LG GAFG V+ + P D ++ VK L + + AR K F E + + L HE+ Sbjct: 541 KRELGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPTLAAR-KDFQREAELLTNLQHEH 599 Query: 355 VVKLVGYCHEGQKKVV 402 +VK G C +G ++ Sbjct: 600 IVKFYGVCGDGDPLIM 615
>NTRK3_PANTR (Q5IS37) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) Length = 825 Score = 39.7 bits (91), Expect = 0.005 Identities = 26/76 (34%), Positives = 40/76 (52%), Gaps = 6/76 (7%) Frame = +1 Query: 193 QRILGTGAFGIVYKG----IMP--DGQIITVKKLAENSPIAREKAFANEVQNIMALHHEN 354 +R LG GAFG V+ + P D ++ VK L + + AR K F E + + L HE+ Sbjct: 541 KRELGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPTLAAR-KDFQREAELLTNLQHEH 599 Query: 355 VVKLVGYCHEGQKKVV 402 +VK G C +G ++ Sbjct: 600 IVKFYGVCGDGDPLIM 615
>NTRK3_MACFA (Q5IFJ9) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) Length = 825 Score = 39.7 bits (91), Expect = 0.005 Identities = 26/76 (34%), Positives = 40/76 (52%), Gaps = 6/76 (7%) Frame = +1 Query: 193 QRILGTGAFGIVYKG----IMP--DGQIITVKKLAENSPIAREKAFANEVQNIMALHHEN 354 +R LG GAFG V+ + P D ++ VK L + + AR K F E + + L HE+ Sbjct: 541 KRELGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPTLAAR-KDFQREAELLTNLQHEH 599 Query: 355 VVKLVGYCHEGQKKVV 402 +VK G C +G ++ Sbjct: 600 IVKFYGVCGDGDPLIM 615
>M3K7_HUMAN (O43318) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1) Length = 606 Score = 39.7 bits (91), Expect = 0.005 Identities = 27/98 (27%), Positives = 50/98 (51%) Frame = +1 Query: 85 SAMSTSAGGGQPSVLSTLPKNLPLDFVKTITDQFSEQRILGTGAFGIVYKGIMPDGQIIT 264 SA S+S+ ++ P + L+F + + + ++G GAFG+V K + + Sbjct: 5 SAASSSSSSSAGEMIEA-PSQV-LNFEEIDYKEIEVEEVVGRGAFGVVCKAKWR-AKDVA 61 Query: 265 VKKLAENSPIAREKAFANEVQNIMALHHENVVKLVGYC 378 +K++ S KAF E++ + ++H N+VKL G C Sbjct: 62 IKQIESES---ERKAFIVELRQLSRVNHPNIVKLYGAC 96
>CDC2_RANDY (Q9W739) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) Length = 302 Score = 39.7 bits (91), Expect = 0.005 Identities = 21/66 (31%), Positives = 36/66 (54%), Gaps = 2/66 (3%) Frame = +1 Query: 178 DQFSEQRILGTGAFGIVYKGI-MPDGQIITVKKL-AENSPIAREKAFANEVQNIMALHHE 351 D++++ +G G +G+VYKG+ GQI+ +KK+ EN E+ + L H Sbjct: 2 DEYAKIEKIGEGTYGVVYKGVHKATGQIVAMKKIRLENEEEGVPSTAIREISLLKELQHP 61 Query: 352 NVVKLV 369 N+V L+ Sbjct: 62 NIVCLL 67
>TOR_DROME (P18475) Tyrosine-protein kinase receptor torso precursor (EC| 2.7.10.1) Length = 923 Score = 39.7 bits (91), Expect = 0.005 Identities = 33/103 (32%), Positives = 47/103 (45%), Gaps = 1/103 (0%) Frame = +1 Query: 193 QRILGTGAFGIVYKGIMPDGQIITVKKLAENSPIAREKAFANEVQNIMAL-HHENVVKLV 369 Q +LG GAFG+V +G+ Q + VK L + AF E+Q + A+ H N+V +V Sbjct: 478 QDVLGEGAFGLVRRGVYKKRQ-VAVKLLKDEPNDEDVYAFKCEIQMLKAVGKHPNIVGIV 536 Query: 370 GYCHEGQKKVVQNNGRYIVADIVESLLCHEYVPKGSLQKNLFE 498 GY ++ +L EY GSLQ L E Sbjct: 537 GYSTRFSNQM---------------MLLIEYCSLGSLQNFLRE 564
>NTRK3_RAT (Q03351) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (GP145-TrkC) (Trk-C) Length = 864 Score = 39.7 bits (91), Expect = 0.005 Identities = 26/76 (34%), Positives = 40/76 (52%), Gaps = 6/76 (7%) Frame = +1 Query: 193 QRILGTGAFGIVYKG----IMP--DGQIITVKKLAENSPIAREKAFANEVQNIMALHHEN 354 +R LG GAFG V+ + P D ++ VK L + + AR K F E + + L HE+ Sbjct: 541 KRELGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPTLAAR-KDFQREAELLTNLQHEH 599 Query: 355 VVKLVGYCHEGQKKVV 402 +VK G C +G ++ Sbjct: 600 IVKFYGVCGDGDPLIM 615
>NTRK3_HUMAN (Q16288) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (GP145-TrkC) (Trk-C) Length = 839 Score = 39.7 bits (91), Expect = 0.005 Identities = 26/76 (34%), Positives = 40/76 (52%), Gaps = 6/76 (7%) Frame = +1 Query: 193 QRILGTGAFGIVYKG----IMP--DGQIITVKKLAENSPIAREKAFANEVQNIMALHHEN 354 +R LG GAFG V+ + P D ++ VK L + + AR K F E + + L HE+ Sbjct: 541 KRELGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPTLAAR-KDFQREAELLTNLQHEH 599 Query: 355 VVKLVGYCHEGQKKVV 402 +VK G C +G ++ Sbjct: 600 IVKFYGVCGDGDPLIM 615
>IPL1_ASHGO (Q755C4) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 367 Score = 39.3 bits (90), Expect = 0.007 Identities = 32/106 (30%), Positives = 46/106 (43%), Gaps = 3/106 (2%) Frame = +1 Query: 184 FSEQRILGTGAFGIVYKGIMPDGQIITVKKLAENSPIAR---EKAFANEVQNIMALHHEN 354 F ++LG G FG VY + + K E I + EK F EV+ +L H N Sbjct: 109 FEIGKVLGKGKFGRVYCVRHIESGFVCALKAMEKKDIIQYNIEKQFRREVEIQSSLRHPN 168 Query: 355 VVKLVGYCHEGQKKVVQNNGRYIVADIVESLLCHEYVPKGSLQKNL 492 + +L GY H+ +K+V L EY+ G L K+L Sbjct: 169 LTQLYGYFHD-EKRV---------------YLLMEYLVNGELYKHL 198
>TNI3K_MOUSE (Q5GIG6) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 833 Score = 39.3 bits (90), Expect = 0.007 Identities = 34/109 (31%), Positives = 57/109 (52%), Gaps = 4/109 (3%) Frame = +1 Query: 199 ILGTGAFGIVYKGIMPDGQIITVKKLAENSPIAREKA--FANEVQNIMALHHENVVKLVG 372 I+G+G+FG VYKG + +I+ +K+ N+ ++ F EV + L+H VV+ VG Sbjct: 466 IIGSGSFGKVYKGRCRN-KIVAIKRYRANTYCSKSDVDMFCREVSILCQLNHPCVVQFVG 524 Query: 373 YCHE--GQKKVVQNNGRYIVADIVESLLCHEYVPKGSLQKNLFEVDTKM 513 C + Q +V +YI + SLL HE QK + ++ +K+ Sbjct: 525 ACLDDPSQFAIVT---QYISGGSLFSLL-HE-------QKRILDLQSKL 562
>TNI3K_RAT (Q7TQP6) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 834 Score = 39.3 bits (90), Expect = 0.007 Identities = 34/109 (31%), Positives = 57/109 (52%), Gaps = 4/109 (3%) Frame = +1 Query: 199 ILGTGAFGIVYKGIMPDGQIITVKKLAENSPIAREKA--FANEVQNIMALHHENVVKLVG 372 I+G+G+FG VYKG + +I+ +K+ N+ ++ F EV + L+H VV+ VG Sbjct: 467 IIGSGSFGKVYKGRCRN-KIVAIKRYRANTYCSKSDVDMFCREVSILCQLNHPCVVQFVG 525 Query: 373 YCHE--GQKKVVQNNGRYIVADIVESLLCHEYVPKGSLQKNLFEVDTKM 513 C + Q +V +YI + SLL HE QK + ++ +K+ Sbjct: 526 ACLDDPSQFAIVT---QYISGGSLFSLL-HE-------QKRILDLQSKL 563
>PHO85_DEBHA (Q6BRY2) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 330 Score = 39.3 bits (90), Expect = 0.007 Identities = 22/74 (29%), Positives = 35/74 (47%), Gaps = 1/74 (1%) Frame = +1 Query: 175 TDQFSEQRILGTGAFGIVYKGI-MPDGQIITVKKLAENSPIAREKAFANEVQNIMALHHE 351 + QF + LG G + VYKG +GQ++ +K++ +S E+ + L HE Sbjct: 5 SSQFQQLEKLGEGTYATVYKGRNRTNGQLVALKEINLDSEEGTPSTAIREISLMKELDHE 64 Query: 352 NVVKLVGYCHEGQK 393 N+V L H K Sbjct: 65 NIVTLYDVIHTENK 78
>RAF_MSV36 (P00532) Serine/threonine-protein kinase transforming protein raf| (EC 2.7.11.1) Length = 323 Score = 38.9 bits (89), Expect = 0.009 Identities = 20/67 (29%), Positives = 36/67 (53%) Frame = +1 Query: 202 LGTGAFGIVYKGIMPDGQIITVKKLAENSPIAREKAFANEVQNIMALHHENVVKLVGYCH 381 +G+G+FG VYKG + + K+ + +P + +AF NEV + H N++ +GY Sbjct: 30 IGSGSFGTVYKGKWHGDVAVKILKVVDPTP-EQLQAFRNEVAVLRKTRHVNILLFMGYMT 88 Query: 382 EGQKKVV 402 + +V Sbjct: 89 KDNLAIV 95
>RAF1_CHICK (P05625) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (RAF-1) (C-RAF) (MIL proto-oncogene serine/threonine-protein kinase) (C-MIL) Length = 647 Score = 38.9 bits (89), Expect = 0.009 Identities = 20/67 (29%), Positives = 36/67 (53%) Frame = +1 Query: 202 LGTGAFGIVYKGIMPDGQIITVKKLAENSPIAREKAFANEVQNIMALHHENVVKLVGYCH 381 +G+G+FG VYKG + + K+ + +P + +AF NEV + H N++ +GY Sbjct: 355 IGSGSFGTVYKGKWHGDVAVKILKVVDPTP-EQFQAFRNEVAVLRKTRHVNILLFMGYMT 413 Query: 382 EGQKKVV 402 + +V Sbjct: 414 KDNLAIV 420
>NTRK1_CHICK (Q91009) High affinity nerve growth factor receptor precursor (EC| 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (Trk-A) (Fragment) Length = 778 Score = 38.9 bits (89), Expect = 0.009 Identities = 25/73 (34%), Positives = 39/73 (53%), Gaps = 6/73 (8%) Frame = +1 Query: 202 LGTGAFGIVYKG----IMPDGQ--IITVKKLAENSPIAREKAFANEVQNIMALHHENVVK 363 LG GAFG V+ ++P+ + ++ VK L E + AR F E + + L HE++VK Sbjct: 499 LGEGAFGKVFLAECSHLLPEQEKTLVAVKALKEVTENARLD-FQREAELLTVLQHEHIVK 557 Query: 364 LVGYCHEGQKKVV 402 G C EG ++ Sbjct: 558 FYGVCTEGDPLIM 570
>KSG8_ARATH (Q96287) Shaggy-related protein kinase theta (EC 2.7.11.1)| (ASK-theta) Length = 472 Score = 38.9 bits (89), Expect = 0.009 Identities = 22/66 (33%), Positives = 38/66 (57%), Gaps = 2/66 (3%) Frame = +1 Query: 175 TDQFSEQRILGTGAFGIVYKG-IMPDGQIITVKKLAENSPIAREKAFANEVQNIMALH-H 348 T + QR++GTG+FG+V++ + G+ + +KK + ++K + N IM L H Sbjct: 135 TISYMAQRVVGTGSFGVVFQAKCLETGEQVAIKK------VLQDKRYKNRELQIMRLQDH 188 Query: 349 ENVVKL 366 NVV+L Sbjct: 189 PNVVRL 194
>MOS_DENAN (Q8AX01) Serine/threonine-protein kinase mos (EC 2.7.11.1) (Oocyte| maturation factor mos) (Fragment) Length = 194 Score = 38.9 bits (89), Expect = 0.009 Identities = 34/106 (32%), Positives = 53/106 (50%), Gaps = 2/106 (1%) Frame = +1 Query: 58 SSPQXLVQPSAMSTSAGGGQPSVLSTLPKNLPLDFVKTITDQFSEQRILGTGAFGIVYKG 237 SSP LV P+ G G S + LP +L + +Q +LG+G FG VYK Sbjct: 9 SSP--LVCPAKGEKFFGVGSTSRIRRLPPHLA--WCSIDWEQLCLLNLLGSGGFGSVYKA 64 Query: 238 IMPDGQIITVKKL--AENSPIAREKAFANEVQNIMALHHENVVKLV 369 G + VK++ + +A ++F E+ N++ L H NVV++V Sbjct: 65 TY-HGATVAVKQVNRCSKNHLASRQSFWAEL-NVVRLDHNNVVRIV 108
>KSGT_BRANA (O04160) Shaggy-related protein kinase theta (EC 2.7.11.1)| (ASK-theta) Length = 468 Score = 38.9 bits (89), Expect = 0.009 Identities = 22/66 (33%), Positives = 38/66 (57%), Gaps = 2/66 (3%) Frame = +1 Query: 175 TDQFSEQRILGTGAFGIVYKG-IMPDGQIITVKKLAENSPIAREKAFANEVQNIMALH-H 348 T + QR++GTG+FG+V++ + G+ + +KK + ++K + N IM L H Sbjct: 131 TISYMAQRVVGTGSFGVVFQAKCLETGEQVAIKK------VLQDKRYKNRELQIMRLQDH 184 Query: 349 ENVVKL 366 NVV+L Sbjct: 185 PNVVRL 190
>CDKL2_RAT (Q5XIT0) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| Length = 507 Score = 38.9 bits (89), Expect = 0.009 Identities = 30/116 (25%), Positives = 58/116 (50%), Gaps = 8/116 (6%) Frame = +1 Query: 178 DQFSEQRILGTGAFGIVYKGIMPD-GQIITVKKLAENSPIAREKAFA-NEVQNIMALHHE 351 +++ ++G G++G+V K D G+I+ +KK E+ K A E++ + L HE Sbjct: 2 EKYENLGLVGEGSYGMVMKCRNKDSGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHE 61 Query: 352 NVVKLVGYCHEGQKKVVQNNGRYIVADIVESLLCHE--YVPKG----SLQKNLFEV 501 N+V L+ C + ++ Y+V + V+ + + P G +QK LF++ Sbjct: 62 NLVNLLEVCKKKKR-------WYLVFEFVDHTILDDLKLFPNGLDYQVVQKYLFQI 110
>TNI3K_HUMAN (Q59H18) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 936 Score = 38.9 bits (89), Expect = 0.009 Identities = 39/131 (29%), Positives = 66/131 (50%), Gaps = 5/131 (3%) Frame = +1 Query: 136 LPKNLPLDFVKTITD-QFSEQRILGTGAFGIVYKGIMPDGQIITVKKLAENSPIAREKA- 309 L LP F +++ +F E I+G+G+FG VYKG + +I+ +K+ N+ ++ Sbjct: 549 LRAGLPSHFHLQLSEIEFHE--IIGSGSFGKVYKGRCRN-KIVAIKRYRANTYCSKSDVD 605 Query: 310 -FANEVQNIMALHHENVVKLVGYC--HEGQKKVVQNNGRYIVADIVESLLCHEYVPKGSL 480 F EV + L+H V++ VG C Q +V +YI + SLL HE Sbjct: 606 MFCREVSILCQLNHPCVIQFVGACLNDPSQFAIVT---QYISGGSLFSLL-HE------- 654 Query: 481 QKNLFEVDTKM 513 QK + ++ +K+ Sbjct: 655 QKRILDLQSKL 665
>RAF1_RAT (P11345) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Raf-1) (C-RAF) (cRaf) Length = 648 Score = 38.9 bits (89), Expect = 0.009 Identities = 20/67 (29%), Positives = 36/67 (53%) Frame = +1 Query: 202 LGTGAFGIVYKGIMPDGQIITVKKLAENSPIAREKAFANEVQNIMALHHENVVKLVGYCH 381 +G+G+FG VYKG + + K+ + +P + +AF NEV + H N++ +GY Sbjct: 355 IGSGSFGTVYKGKWHGDVAVKILKVVDPTP-EQLQAFRNEVAVLRKTRHVNILLFMGYMT 413 Query: 382 EGQKKVV 402 + +V Sbjct: 414 KDNLAIV 420
>RAF1_MOUSE (Q99N57) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Raf-1) (C-RAF) (cRaf) Length = 648 Score = 38.9 bits (89), Expect = 0.009 Identities = 20/67 (29%), Positives = 36/67 (53%) Frame = +1 Query: 202 LGTGAFGIVYKGIMPDGQIITVKKLAENSPIAREKAFANEVQNIMALHHENVVKLVGYCH 381 +G+G+FG VYKG + + K+ + +P + +AF NEV + H N++ +GY Sbjct: 355 IGSGSFGTVYKGKWHGDVAVKILKVVDPTP-EQLQAFRNEVAVLRKTRHVNILLFMGYMT 413 Query: 382 EGQKKVV 402 + +V Sbjct: 414 KDNLAIV 420
>RAF1_HUMAN (P04049) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Raf-1) (C-RAF) (cRaf) Length = 648 Score = 38.9 bits (89), Expect = 0.009 Identities = 20/67 (29%), Positives = 36/67 (53%) Frame = +1 Query: 202 LGTGAFGIVYKGIMPDGQIITVKKLAENSPIAREKAFANEVQNIMALHHENVVKLVGYCH 381 +G+G+FG VYKG + + K+ + +P + +AF NEV + H N++ +GY Sbjct: 355 IGSGSFGTVYKGKWHGDVAVKILKVVDPTP-EQFQAFRNEVAVLRKTRHVNILLFMGYMT 413 Query: 382 EGQKKVV 402 + +V Sbjct: 414 KDNLAIV 420
>TNI3K_PONPY (Q5RF15) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) Length = 617 Score = 38.9 bits (89), Expect = 0.009 Identities = 39/131 (29%), Positives = 66/131 (50%), Gaps = 5/131 (3%) Frame = +1 Query: 136 LPKNLPLDFVKTITD-QFSEQRILGTGAFGIVYKGIMPDGQIITVKKLAENSPIAREKA- 309 L LP F +++ +F E I+G+G+FG VYKG + +I+ +K+ N+ ++ Sbjct: 447 LRAGLPSHFHLQLSEIEFHE--IIGSGSFGKVYKGRCRN-KIVAIKRYRANTYCSKSDVD 503 Query: 310 -FANEVQNIMALHHENVVKLVGYC--HEGQKKVVQNNGRYIVADIVESLLCHEYVPKGSL 480 F EV + L+H V++ VG C Q +V +YI + SLL HE Sbjct: 504 MFCREVSILCQLNHPCVIQFVGACLNDPSQFAIVT---QYISGGSLFSLL-HE------- 552 Query: 481 QKNLFEVDTKM 513 QK + ++ +K+ Sbjct: 553 QKRILDLQSKL 563
>CDKL3_MACFA (Q4R8T9) Cyclin-dependent kinase-like 3 (EC 2.7.11.22)| Length = 590 Score = 38.9 bits (89), Expect = 0.009 Identities = 31/109 (28%), Positives = 53/109 (48%), Gaps = 3/109 (2%) Frame = +1 Query: 202 LGTGAFGIVYKGIMPD-GQIITVKKLAENSPIAREKAFANEVQNIMALHHENVVKLVGYC 378 +G G++G V K + GQI+ +K E + K E++ + HHEN+V L+ Sbjct: 10 VGEGSYGTVMKCKHKNTGQIVAIKIFYERPEQSVNKIAMREIKFLKQFHHENLVNLIEVF 69 Query: 379 HEGQKKVVQNNGRYIVADIVESL--LCHEYVPKGSLQKNLFEVDTKMDW 519 QKK + +I +++ L CH K L+K LF++ +D+ Sbjct: 70 R--QKKKIHLVFEFIDHTVLDELQHYCHGLESK-RLRKYLFQILRAIDY 115
>CDKL3_HUMAN (Q8IVW4) Cyclin-dependent kinase-like 3 (EC 2.7.11.22)| (Serine/threonine protein kinase NKIAMRE) Length = 592 Score = 38.9 bits (89), Expect = 0.009 Identities = 31/109 (28%), Positives = 53/109 (48%), Gaps = 3/109 (2%) Frame = +1 Query: 202 LGTGAFGIVYKGIMPD-GQIITVKKLAENSPIAREKAFANEVQNIMALHHENVVKLVGYC 378 +G G++G V K + GQI+ +K E + K E++ + HHEN+V L+ Sbjct: 10 VGEGSYGTVMKCKHKNTGQIVAIKIFYERPEQSVNKIAMREIKFLKQFHHENLVNLIEVF 69 Query: 379 HEGQKKVVQNNGRYIVADIVESL--LCHEYVPKGSLQKNLFEVDTKMDW 519 QKK + +I +++ L CH K L+K LF++ +D+ Sbjct: 70 R--QKKKIHLVFEFIDHTVLDELQHYCHGLESK-RLRKYLFQILRAIDY 115
>CDKL2_MOUSE (Q9QUK0) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| (Serine/threonine-protein kinase KKIAMRE) Length = 568 Score = 38.9 bits (89), Expect = 0.009 Identities = 30/116 (25%), Positives = 58/116 (50%), Gaps = 8/116 (6%) Frame = +1 Query: 178 DQFSEQRILGTGAFGIVYKGIMPD-GQIITVKKLAENSPIAREKAFA-NEVQNIMALHHE 351 +++ ++G G++G+V K D G+I+ +KK E+ K A E++ + L HE Sbjct: 2 EKYENLGLVGEGSYGMVMKCRNKDSGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHE 61 Query: 352 NVVKLVGYCHEGQKKVVQNNGRYIVADIVESLLCHE--YVPKG----SLQKNLFEV 501 N+V L+ C + ++ Y+V + V+ + + P G +QK LF++ Sbjct: 62 NLVNLLEVCKKKKR-------WYLVFEFVDHTILDDLKLFPNGLDYQVVQKYLFQI 110
>MIL_AVIMH (P00531) Serine/threonine-protein kinase transforming protein mil| (EC 2.7.11.1) Length = 380 Score = 38.9 bits (89), Expect = 0.009 Identities = 20/67 (29%), Positives = 36/67 (53%) Frame = +1 Query: 202 LGTGAFGIVYKGIMPDGQIITVKKLAENSPIAREKAFANEVQNIMALHHENVVKLVGYCH 381 +G+G+FG VYKG + + K+ + +P + +AF NEV + H N++ +GY Sbjct: 88 IGSGSFGTVYKGKWHGDVAVKILKVVDPTP-EQFQAFRNEVAVLRKTRHVNILLFMGYMT 146 Query: 382 EGQKKVV 402 + +V Sbjct: 147 KDNLAIV 153
>RAF1_XENLA (P09560) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (C-RAF) Length = 638 Score = 38.9 bits (89), Expect = 0.009 Identities = 20/67 (29%), Positives = 36/67 (53%) Frame = +1 Query: 202 LGTGAFGIVYKGIMPDGQIITVKKLAENSPIAREKAFANEVQNIMALHHENVVKLVGYCH 381 +G+G+FG VYKG + + K+ + +P + +AF NEV + H N++ +GY Sbjct: 346 IGSGSFGTVYKGKWHGDVAVKILKVTDPTP-EQLQAFRNEVAVLRKTRHVNILLFMGYMT 404 Query: 382 EGQKKVV 402 + +V Sbjct: 405 KDNLAIV 411
>KPEL_DROME (Q05652) Probable serine/threonine-protein kinase pelle (EC| 2.7.11.1) Length = 501 Score = 38.9 bits (89), Expect = 0.009 Identities = 26/89 (29%), Positives = 45/89 (50%), Gaps = 7/89 (7%) Frame = +1 Query: 148 LPLDF--VKTITDQFSEQRILGTGAFGIVYKGIMPDGQIITVKKLAENSPIAREKAFA-- 315 L +D+ ++ TD +S LG G FG VY+G + +K + SP +K Sbjct: 199 LEIDYAELENATDGWSPDNRLGQGGFGDVYRGKWKQLDV-AIKVMNYRSPNIDQKMVELQ 257 Query: 316 ---NEVQNIMALHHENVVKLVGYCHEGQK 393 NE++ + ++ H+N++ L GY +G K Sbjct: 258 QSYNELKYLNSIRHDNILALYGYSIKGGK 286
>SRK2_SPOLA (P42688) Tyrosine-protein kinase SRK2 (EC 2.7.10.2) (Fragment)| Length = 362 Score = 38.5 bits (88), Expect = 0.012 Identities = 22/71 (30%), Positives = 35/71 (49%) Frame = +1 Query: 178 DQFSEQRILGTGAFGIVYKGIMPDGQIITVKKLAENSPIAREKAFANEVQNIMALHHENV 357 D + R LG G FG VY+G+ + + VK L + + AF E Q + L H + Sbjct: 93 DSITLIRKLGAGQFGEVYQGLWNNSTPVAVKTLKAGT--MQPAAFLAEAQIMKKLRHPKL 150 Query: 358 VKLVGYCHEGQ 390 ++L C +G+ Sbjct: 151 IQLYAVCTQGE 161
>RMIL_AVII1 (P10533) Serine/threonine-protein kinase transforming protein Rmil| (EC 2.7.11.1) Length = 367 Score = 38.5 bits (88), Expect = 0.012 Identities = 23/68 (33%), Positives = 37/68 (54%), Gaps = 1/68 (1%) Frame = +1 Query: 202 LGTGAFGIVYKGIMPDGQIITVKKLAENSPIARE-KAFANEVQNIMALHHENVVKLVGYC 378 +G+G+FG VYKG + VK L +P ++ +AF NEV + H N++ +GY Sbjct: 73 IGSGSFGTVYKGKWHGD--VAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYS 130 Query: 379 HEGQKKVV 402 + Q +V Sbjct: 131 TKPQLAIV 138
>RMIL_AVEVR (P27966) Serine/threonine-protein kinase transforming protein Rmil| (EC 2.7.11.1) Length = 450 Score = 38.5 bits (88), Expect = 0.012 Identities = 23/68 (33%), Positives = 37/68 (54%), Gaps = 1/68 (1%) Frame = +1 Query: 202 LGTGAFGIVYKGIMPDGQIITVKKLAENSPIARE-KAFANEVQNIMALHHENVVKLVGYC 378 +G+G+FG VYKG + VK L +P ++ +AF NEV + H N++ +GY Sbjct: 89 IGSGSFGTVYKGKWHGD--VAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYS 146 Query: 379 HEGQKKVV 402 + Q +V Sbjct: 147 TKPQLAIV 154
>CRK1_LEIME (Q06309) Cell division protein kinase 2 homolog CRK1 (EC 2.7.11.23)| Length = 301 Score = 38.5 bits (88), Expect = 0.012 Identities = 21/79 (26%), Positives = 38/79 (48%), Gaps = 2/79 (2%) Frame = +1 Query: 172 ITDQFSEQRILGTGAFGIVYKGI-MPDGQIITVKKLAENSPIAREKAFA-NEVQNIMALH 345 +T ++ Q +G G +G+VYK + +K++ +S A E+ + L Sbjct: 1 MTSRYERQEKIGEGTYGVVYKARDTSTAATVALKRIRLDSEEEGVPCTAIREISLLKELR 60 Query: 346 HENVVKLVGYCHEGQKKVV 402 HEN+VKL+ CH + + Sbjct: 61 HENIVKLLDVCHSEHRLTI 79
>NTRK1_RAT (P35739) High affinity nerve growth factor receptor precursor (EC| 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (p140-TrkA) (Slow nerve growth factor receptor) (Trk-A) Length = 799 Score = 38.5 bits (88), Expect = 0.012 Identities = 24/68 (35%), Positives = 34/68 (50%), Gaps = 6/68 (8%) Frame = +1 Query: 202 LGTGAFGIVYKGIM------PDGQIITVKKLAENSPIAREKAFANEVQNIMALHHENVVK 363 LG GAFG V+ D ++ VK L E S AR+ F E + + L H+++V+ Sbjct: 519 LGEGAFGKVFLAECYNLLNDQDKMLVAVKALKETSENARQD-FHREAELLTMLQHQHIVR 577 Query: 364 LVGYCHEG 387 G C EG Sbjct: 578 FFGVCTEG 585
>BRAF1_COTJA (P34908) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (RMIL serine/threonine-protein kinase) (c-RMIL) Length = 807 Score = 38.5 bits (88), Expect = 0.012 Identities = 23/68 (33%), Positives = 37/68 (54%), Gaps = 1/68 (1%) Frame = +1 Query: 202 LGTGAFGIVYKGIMPDGQIITVKKLAENSPIARE-KAFANEVQNIMALHHENVVKLVGYC 378 +G+G+FG VYKG + VK L +P ++ +AF NEV + H N++ +GY Sbjct: 503 IGSGSFGTVYKGKWHGD--VAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYS 560 Query: 379 HEGQKKVV 402 + Q +V Sbjct: 561 TKPQLAIV 568
>INSR_RAT (P15127) Insulin receptor precursor (EC 2.7.10.1) (IR) [Contains:| Insulin receptor alpha subunit; Insulin receptor beta subunit] Length = 1383 Score = 38.5 bits (88), Expect = 0.012 Identities = 24/75 (32%), Positives = 40/75 (53%), Gaps = 6/75 (8%) Frame = +1 Query: 196 RILGTGAFGIVYKGIMPD---GQI---ITVKKLAENSPIAREKAFANEVQNIMALHHENV 357 R LG G+FG+VY+G D G++ + VK + E++ + F NE + +V Sbjct: 1028 RELGQGSFGMVYEGNAKDIIKGEVETRVAVKTVNESASLRERIEFLNEASVMKGFTCHHV 1087 Query: 358 VKLVGYCHEGQKKVV 402 V+L+G +GQ +V Sbjct: 1088 VRLLGVVSKGQPTLV 1102
>BRAF1_CHICK (Q04982) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Rmil serine/threonine-protein kinase) (c-Rmil) Length = 806 Score = 38.5 bits (88), Expect = 0.012 Identities = 23/68 (33%), Positives = 37/68 (54%), Gaps = 1/68 (1%) Frame = +1 Query: 202 LGTGAFGIVYKGIMPDGQIITVKKLAENSPIARE-KAFANEVQNIMALHHENVVKLVGYC 378 +G+G+FG VYKG + VK L +P ++ +AF NEV + H N++ +GY Sbjct: 503 IGSGSFGTVYKGKWHGD--VAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYS 560 Query: 379 HEGQKKVV 402 + Q +V Sbjct: 561 TKPQLAIV 568
>TRK1_LYMST (O76997) Putative neurotrophin receptor LTRK 1 precursor (EC| 2.7.10.1) Length = 794 Score = 38.5 bits (88), Expect = 0.012 Identities = 25/96 (26%), Positives = 43/96 (44%), Gaps = 6/96 (6%) Frame = +1 Query: 124 VLSTLPKNLPLDFVKTITDQFSEQRILGTGAFGIVYKGIMP------DGQIITVKKLAEN 285 V +T PK + L + + R++G GAFG V+ G + I+ VK L + Sbjct: 491 VATTCPKTVRLQTILLM-------RVIGEGAFGRVFLGTCAHLIQKNEFAIVAVKTLKGS 543 Query: 286 SPIAREKAFANEVQNIMALHHENVVKLVGYCHEGQK 393 + ++ F E + + + H N+V G C E + Sbjct: 544 CSDSLKRDFEREAEMLATIEHANIVTFYGVCTESDQ 579
>ROR1_HUMAN (Q01973) Tyrosine-protein kinase transmembrane receptor ROR1| precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1) Length = 937 Score = 38.5 bits (88), Expect = 0.012 Identities = 28/82 (34%), Positives = 40/82 (48%), Gaps = 5/82 (6%) Frame = +1 Query: 142 KNLPLDFVKTITDQFSEQRILGTGAFGIVYKGI-----MPDGQIITVKKLAENSPIAREK 306 K LPL V+ F E+ LG AFG +YKG M Q++ +K L + + + Sbjct: 466 KELPLSAVR-----FMEE--LGECAFGKIYKGHLYLPGMDHAQLVAIKTLKDYNNPQQWM 518 Query: 307 AFANEVQNIMALHHENVVKLVG 372 F E + LHH N+V L+G Sbjct: 519 EFQQEASLMAELHHPNIVCLLG 540
>PHO85_YARLI (Q6C7U8) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 294 Score = 38.5 bits (88), Expect = 0.012 Identities = 22/74 (29%), Positives = 34/74 (45%), Gaps = 1/74 (1%) Frame = +1 Query: 175 TDQFSEQRILGTGAFGIVYKGI-MPDGQIITVKKLAENSPIAREKAFANEVQNIMALHHE 351 + QF + LG G + VYKG GQ++ +K++ +S E+ + L HE Sbjct: 4 SSQFQQLEKLGEGTYATVYKGRNRTTGQLVALKEINLDSEEGTPSTAIREISLMKELKHE 63 Query: 352 NVVKLVGYCHEGQK 393 N+V L H K Sbjct: 64 NIVTLYDVIHTENK 77
>7LESS_DROME (P13368) Protein sevenless (EC 2.7.10.1)| Length = 2554 Score = 38.5 bits (88), Expect = 0.012 Identities = 35/124 (28%), Positives = 52/124 (41%), Gaps = 6/124 (4%) Frame = +1 Query: 31 NHPQCWXFSSSPQXLVQPSAMSTSAGGGQPSVLSTLPKNLPLDFVKTIT-DQFSEQRILG 207 + P W S+ Q Q A+ A ST + + + I Q R LG Sbjct: 2164 SRPSIWSNLSTLQTQQQLMAVRNRA-------FSTTLSDADIALLPQINWSQLKLLRFLG 2216 Query: 208 TGAFGIVYKGIM-----PDGQIITVKKLAENSPIAREKAFANEVQNIMALHHENVVKLVG 372 +GAFG VY+G + + Q + +K L + + E E Q + HEN+V LVG Sbjct: 2217 SGAFGEVYEGQLKTEDSEEPQRVAIKSLRKGASEFAE--LLQEAQLMSNFKHENIVCLVG 2274 Query: 373 YCHE 384 C + Sbjct: 2275 ICFD 2278
>BRAF1_MOUSE (P28028) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Fragment) Length = 328 Score = 38.5 bits (88), Expect = 0.012 Identities = 23/68 (33%), Positives = 37/68 (54%), Gaps = 1/68 (1%) Frame = +1 Query: 202 LGTGAFGIVYKGIMPDGQIITVKKLAENSPIARE-KAFANEVQNIMALHHENVVKLVGYC 378 +G+G+FG VYKG + VK L +P ++ +AF NEV + H N++ +GY Sbjct: 25 IGSGSFGTVYKGKWHGD--VAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYS 82 Query: 379 HEGQKKVV 402 + Q +V Sbjct: 83 TKPQLAIV 90
>BMPR2_HUMAN (Q13873) Bone morphogenetic protein receptor type-2 precursor (EC| 2.7.11.30) (Bone morphogenetic protein receptor type II) (BMP type II receptor) (BMPR-II) Length = 1038 Score = 38.5 bits (88), Expect = 0.012 Identities = 32/107 (29%), Positives = 51/107 (47%), Gaps = 2/107 (1%) Frame = +1 Query: 178 DQFSEQRILGTGAFGIVYKGIMPDGQIITVKKLAENSPIAREKAFANE--VQNIMALHHE 351 D ++G G +G VYKG + D + + VK + A + F NE + + + H+ Sbjct: 201 DNLKLLELIGRGRYGAVYKGSL-DERPVAVKVFS----FANRQNFINEKNIYRVPLMEHD 255 Query: 352 NVVKLVGYCHEGQKKVVQNNGRYIVADIVESLLCHEYVPKGSLQKNL 492 N+ + + G ++V + GR +E LL EY P GSL K L Sbjct: 256 NIARFI----VGDERVTAD-GR------MEYLLVMEYYPNGSLCKYL 291
>BRAF1_HUMAN (P15056) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (p94) (v-Raf murine sarcoma viral oncogene homolog B1) Length = 766 Score = 38.5 bits (88), Expect = 0.012 Identities = 23/68 (33%), Positives = 37/68 (54%), Gaps = 1/68 (1%) Frame = +1 Query: 202 LGTGAFGIVYKGIMPDGQIITVKKLAENSPIARE-KAFANEVQNIMALHHENVVKLVGYC 378 +G+G+FG VYKG + VK L +P ++ +AF NEV + H N++ +GY Sbjct: 463 IGSGSFGTVYKGKWHGD--VAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYS 520 Query: 379 HEGQKKVV 402 + Q +V Sbjct: 521 TKPQLAIV 528
>TNK1_MOUSE (Q99ML2) Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2)| (Kinase of embryonic stem cells) Length = 666 Score = 38.5 bits (88), Expect = 0.012 Identities = 23/65 (35%), Positives = 37/65 (56%), Gaps = 7/65 (10%) Frame = +1 Query: 199 ILGTGAFGIVYKGI--MPDGQIITVK----KLAENSPIAREKA-FANEVQNIMALHHENV 357 +LG+G FG+V++G+ +P GQ I V ++ P+ E F EV +M L H +V Sbjct: 121 LLGSGCFGVVHRGLWTLPSGQSIPVAVKSLRVGPEGPMGTELGDFLREVSVMMKLEHPHV 180 Query: 358 VKLVG 372 ++L G Sbjct: 181 LRLHG 185
>TESK2_MOUSE (Q8VCT9) Dual specificity testis-specific protein kinase 2 (EC| 2.7.12.1) (Testicular protein kinase 2) Length = 570 Score = 38.5 bits (88), Expect = 0.012 Identities = 32/124 (25%), Positives = 57/124 (45%), Gaps = 2/124 (1%) Frame = +1 Query: 169 TITDQFSEQRILGTGAFGIVYK-GIMPDGQIITVKKLAENSPIAREKAFANEVQNIMALH 345 T D F+ ++I G+G F V+K GQ++ +K N+ + E+Q + L Sbjct: 54 TSLDDFTREKI-GSGFFSEVFKVRHRASGQVMALKM---NTLSSNRANLLKEMQLMNRLS 109 Query: 346 HENVVKLVGYC-HEGQKKVVQNNGRYIVADIVESLLCHEYVPKGSLQKNLFEVDTKMDWS 522 H N+++ +G C H+GQ + EY+ G+L++ L + D + W+ Sbjct: 110 HPNILRFMGVCVHQGQLHALT-----------------EYINSGNLEQ-LLDSDLYLPWT 151 Query: 523 TRFK 534 R K Sbjct: 152 VRVK 155
>BTK_CHICK (Q8JH64) Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton's| tyrosine kinase) Length = 657 Score = 38.5 bits (88), Expect = 0.012 Identities = 22/59 (37%), Positives = 31/59 (52%) Frame = +1 Query: 202 LGTGAFGIVYKGIMPDGQIITVKKLAENSPIAREKAFANEVQNIMALHHENVVKLVGYC 378 LGTG FG+V G + +K + E S E F +E + +M L HE +V+L G C Sbjct: 406 LGTGQFGVVKYGKWRGQYNVAIKMIREGS--MSEDEFIDEAKVMMNLSHEKLVQLYGVC 462
>PHO85_YEAST (P17157) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 305 Score = 38.1 bits (87), Expect = 0.016 Identities = 21/74 (28%), Positives = 34/74 (45%), Gaps = 1/74 (1%) Frame = +1 Query: 175 TDQFSEQRILGTGAFGIVYKGI-MPDGQIITVKKLAENSPIAREKAFANEVQNIMALHHE 351 + QF + LG G + VYKG+ G + +K++ +S E+ + L HE Sbjct: 4 SSQFKQLEKLGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHE 63 Query: 352 NVVKLVGYCHEGQK 393 N+V+L H K Sbjct: 64 NIVRLYDVIHTENK 77
>LIMK1_XENLA (O42565) LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1) (xLIMK1)| Length = 615 Score = 38.1 bits (87), Expect = 0.016 Identities = 27/111 (24%), Positives = 52/111 (46%), Gaps = 1/111 (0%) Frame = +1 Query: 199 ILGTGAFGIVYKGI-MPDGQIITVKKLAENSPIAREKAFANEVQNIMALHHENVVKLVGY 375 +LG G FG K G+++ +K+L ++ F EV+ + L H +V+K +G Sbjct: 319 VLGRGCFGQAIKVTHRVTGEVMVMKELIRFDE-ETQRTFLKEVKVMRCLEHPHVLKFIGV 377 Query: 376 CHEGQKKVVQNNGRYIVADIVESLLCHEYVPKGSLQKNLFEVDTKMDWSTR 528 ++ ++ +I EY+P G+L++ + +DT W+ R Sbjct: 378 LYKDKRL------NFIT----------EYIPGGTLRRVIKSMDTHCPWNQR 412
>FLT3_MOUSE (Q00342) FL cytokine receptor precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor flk-2) (Fetal liver kinase 2) (Tyrosine-protein kinase FLT3) Length = 992 Score = 38.1 bits (87), Expect = 0.016 Identities = 25/68 (36%), Positives = 38/68 (55%), Gaps = 7/68 (10%) Frame = +1 Query: 196 RILGTGAFGIVYK----GIMPDGQII--TVKKLAENSPIAREKAFANEVQNIMAL-HHEN 354 ++LG+GAFG V GI G I VK L E + ++A +E++ + L HH+N Sbjct: 615 KVLGSGAFGRVMNATAYGISKTGVSIQVAVKMLKEKADSCEKEALMSELKMMTHLGHHDN 674 Query: 355 VVKLVGYC 378 +V L+G C Sbjct: 675 IVNLLGAC 682
>JAK1_MOUSE (P52332) Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1)| (JAK-1) Length = 1153 Score = 38.1 bits (87), Expect = 0.016 Identities = 36/123 (29%), Positives = 52/123 (42%), Gaps = 5/123 (4%) Frame = +1 Query: 139 PKNLPLDFVKTITDQFSEQRILGTGAFGIVYK-GIMPDG----QIITVKKLAENSPIARE 303 P + F+K I D LG G FG V P+G + + VK L S Sbjct: 866 PTHFEKRFLKRIRD-------LGEGHFGKVELCRYDPEGDNTGEQVAVKSLKPESGGNHI 918 Query: 304 KAFANEVQNIMALHHENVVKLVGYCHEGQKKVVQNNGRYIVADIVESLLCHEYVPKGSLQ 483 E++ + L+HEN+VK G C E NG ++ + + S EY+PK + Sbjct: 919 ADLKKEIEILRNLYHENIVKYKGICMED-----GGNGIKLIMEFLPSGSLKEYLPKNKNK 973 Query: 484 KNL 492 NL Sbjct: 974 INL 976
>KSG5_ARATH (Q8VZD5) Shaggy-related protein kinase epsilon (EC 2.7.11.1)| (ASK-epsilon) Length = 410 Score = 38.1 bits (87), Expect = 0.016 Identities = 22/66 (33%), Positives = 38/66 (57%), Gaps = 2/66 (3%) Frame = +1 Query: 175 TDQFSEQRILGTGAFGIVYKG-IMPDGQIITVKKLAENSPIAREKAFAN-EVQNIMALHH 348 T + +RI+G G+FGIV++ + G+ + +KK + ++K + N E+Q + L H Sbjct: 71 TISYMAERIVGQGSFGIVFQAKCLETGETVAIKK------VLQDKRYKNRELQTMRLLDH 124 Query: 349 ENVVKL 366 NVV L Sbjct: 125 PNVVSL 130
>BMX_HUMAN (P51813) Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2)| (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38) Length = 675 Score = 38.1 bits (87), Expect = 0.016 Identities = 22/59 (37%), Positives = 28/59 (47%) Frame = +1 Query: 202 LGTGAFGIVYKGIMPDGQIITVKKLAENSPIAREKAFANEVQNIMALHHENVVKLVGYC 378 LG+G FG+V G + VK + E S E F E Q +M L H +VK G C Sbjct: 423 LGSGQFGVVQLGKWKGQYDVAVKMIKEGS--MSEDEFFQEAQTMMKLSHPKLVKFYGVC 479
>KPCD3_HUMAN (O94806) Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein| kinase C nu type) (nPKC-nu) (Protein kinase EPK2) Length = 890 Score = 38.1 bits (87), Expect = 0.016 Identities = 23/70 (32%), Positives = 38/70 (54%), Gaps = 2/70 (2%) Frame = +1 Query: 163 VKTITDQFSEQRILGTGAFGIVYKG-IMPDGQIITVKKLAE-NSPIAREKAFANEVQNIM 336 + T+ F+++ +LG+G FGIVY G G+ + +K + + P +E NEV + Sbjct: 570 ISTVYQIFADE-VLGSGQFGIVYGGKHRKTGRDVAIKVIDKMRFPTKQESQLRNEVAILQ 628 Query: 337 ALHHENVVKL 366 LHH +V L Sbjct: 629 NLHHPGIVNL 638
>BTK_MOUSE (P35991) Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton's| tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) (Kinase EMB) Length = 658 Score = 38.1 bits (87), Expect = 0.016 Identities = 22/59 (37%), Positives = 30/59 (50%) Frame = +1 Query: 202 LGTGAFGIVYKGIMPDGQIITVKKLAENSPIAREKAFANEVQNIMALHHENVVKLVGYC 378 LGTG FG+V G + +K + E S E F E + +M L HE +V+L G C Sbjct: 407 LGTGQFGVVKYGKWRGQYDVAIKMIREGS--MSEDEFIEEAKVMMNLSHEKLVQLYGVC 463
>BTK_HUMAN (Q06187) Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton's| tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) Length = 658 Score = 38.1 bits (87), Expect = 0.016 Identities = 22/59 (37%), Positives = 30/59 (50%) Frame = +1 Query: 202 LGTGAFGIVYKGIMPDGQIITVKKLAENSPIAREKAFANEVQNIMALHHENVVKLVGYC 378 LGTG FG+V G + +K + E S E F E + +M L HE +V+L G C Sbjct: 407 LGTGQFGVVKYGKWRGQYDVAIKMIKEGS--MSEDEFIEEAKVMMNLSHEKLVQLYGVC 463
>GSK3H_DROME (P83101) Putative glycogen synthase kinase-3 homolog (EC 2.7.11.26)| (GSK-3) (Protein gasket) Length = 501 Score = 38.1 bits (87), Expect = 0.016 Identities = 16/63 (25%), Positives = 41/63 (65%), Gaps = 2/63 (3%) Frame = +1 Query: 184 FSEQRILGTGAFGIVYKG-IMPDGQIITVKKLAENSPIAREKAFAN-EVQNIMALHHENV 357 +++ +++G G+FG+V++ ++P +++ +KK + +++ F N E+Q + L H+N+ Sbjct: 33 YTDAKVVGNGSFGVVFQAKMVPSNEMVAIKK------VLQDRRFKNRELQIMRKLRHDNI 86 Query: 358 VKL 366 + L Sbjct: 87 ITL 89
>GSK31_SCHPO (Q9URT9) Protein kinase gsk31 (EC 2.7.11.1)| Length = 381 Score = 37.7 bits (86), Expect = 0.020 Identities = 21/71 (29%), Positives = 41/71 (57%), Gaps = 2/71 (2%) Frame = +1 Query: 175 TDQFSEQRILGTGAFGIVYKG-IMPDGQIITVKKLAENSPIAREKAFAN-EVQNIMALHH 348 T + R+LG+G+FG+V + ++ I VK+ + ++K + N E+Q + A+ H Sbjct: 22 TISYEPCRVLGSGSFGVVIQAKLVGTPGFIAVKR------VLQDKRYKNRELQIMRAISH 75 Query: 349 ENVVKLVGYCH 381 N++KL+ + H Sbjct: 76 PNIIKLIAFFH 86
>LET23_CAEEL (P24348) Receptor tyrosine-protein kinase let-23 precursor (EC| 2.7.10.1) (Lethal protein 23) Length = 1367 Score = 37.7 bits (86), Expect = 0.020 Identities = 23/73 (31%), Positives = 38/73 (52%), Gaps = 6/73 (8%) Frame = +1 Query: 202 LGTGAFGIVYKGIMPDGQIITVK-----KLAENSPIAREKAFANEVQNIMALHHENVVKL 366 LG GAFG V+ GI + VK K+ + ++ E N+ L H+N++K+ Sbjct: 935 LGAGAFGTVFAGIYYPKRAKNVKIPVAIKVFQTDQSQTDEML-EEATNMFRLRHDNLLKI 993 Query: 367 VGYC-HEGQKKVV 402 +G+C H+ K+V Sbjct: 994 IGFCMHDDGLKIV 1006
>KPCD3_MOUSE (Q8K1Y2) Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein| kinase C nu type) (nPKC-nu) Length = 889 Score = 37.7 bits (86), Expect = 0.020 Identities = 31/104 (29%), Positives = 53/104 (50%), Gaps = 10/104 (9%) Frame = +1 Query: 85 SAMSTSAGGGQPSVLST--------LPKNLPLDFVKTITDQFSEQRILGTGAFGIVYKG- 237 +++ TS G G+ L+T + +N+ + V I F+++ +LG+G FGIVY G Sbjct: 538 ASVCTSPGQGKDHNLATSISVSNCQVQENVDISSVYQI---FADE-VLGSGQFGIVYGGK 593 Query: 238 IMPDGQIITVKKLAE-NSPIAREKAFANEVQNIMALHHENVVKL 366 G+ + +K + + P +E NEV + LHH +V L Sbjct: 594 HRKTGRDVAIKVIDKMRFPTKQESQLRNEVAILQNLHHPGIVNL 637
>WEE1_DROME (P54350) Wee1-like protein kinase (EC 2.7.10.2) (Dwee1)| Length = 609 Score = 37.7 bits (86), Expect = 0.020 Identities = 32/113 (28%), Positives = 50/113 (44%), Gaps = 7/113 (6%) Frame = +1 Query: 91 MSTSAGGGQPSVLSTLPKNLPLDF--VKTITDQFSEQRILGTGAFGIVYKGI-MPDGQII 261 ++ AG + PK L L + +F + ++G G FG+V++ + DG I Sbjct: 206 VTEEAGDSMREIHQQAPKRLALHDTNISRFKREFMQVNVIGVGEFGVVFQCVNRLDGCIY 265 Query: 262 TVKKLAENSPIAR---EKAFANEVQNIMAL-HHENVVKLVGYCHEGQKKVVQN 408 +KK P+A EK NEV L H+NVV+ E ++QN Sbjct: 266 AIKK--SKKPVAGSSFEKRALNEVWAHAVLGKHDNVVRYYSAWAEDDHMLIQN 316
>M3K2_ARATH (Q9FZ36) Mitogen-activated protein kinase kinase kinase 2 (EC| 2.7.11.25) (Arabidospsis NPK1-related protein kinase 2) Length = 651 Score = 37.7 bits (86), Expect = 0.020 Identities = 24/73 (32%), Positives = 42/73 (57%), Gaps = 8/73 (10%) Frame = +1 Query: 196 RILGTGAFGIVYKGI-MPDGQIITVKKLAENSPIA-REKAFAN------EVQNIMALHHE 351 +++G GAFG VY G+ + G+++ VK++ S A +EK A+ EV+ + L H Sbjct: 72 QLIGRGAFGTVYMGMNLDSGELLAVKQVLITSNCASKEKTQAHIQELEEEVKLLKNLSHP 131 Query: 352 NVVKLVGYCHEGQ 390 N+V+ +G E + Sbjct: 132 NIVRYLGTVREDE 144
>CDC2H_PLACH (Q4Y4B1) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 288 Score = 37.7 bits (86), Expect = 0.020 Identities = 19/68 (27%), Positives = 32/68 (47%), Gaps = 1/68 (1%) Frame = +1 Query: 202 LGTGAFGIVYKGIMPDGQIITVKKL-AENSPIAREKAFANEVQNIMALHHENVVKLVGYC 378 +G G +G+VYK DG+ +KK+ E E+ + L H N+VKL Sbjct: 10 IGEGTYGVVYKAQNSDGESFALKKIRLEKEDEGIPSTAIREISILKELRHSNIVKLYDVI 69 Query: 379 HEGQKKVV 402 H ++ ++ Sbjct: 70 HAKKRLIL 77
>CDC2H_PLABA (Q4Z6R1) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 288 Score = 37.7 bits (86), Expect = 0.020 Identities = 19/68 (27%), Positives = 32/68 (47%), Gaps = 1/68 (1%) Frame = +1 Query: 202 LGTGAFGIVYKGIMPDGQIITVKKL-AENSPIAREKAFANEVQNIMALHHENVVKLVGYC 378 +G G +G+VYK DG+ +KK+ E E+ + L H N+VKL Sbjct: 10 IGEGTYGVVYKAQNSDGESFALKKIRLEKEDEGIPSTAIREISILKELRHSNIVKLYDVI 69 Query: 379 HEGQKKVV 402 H ++ ++ Sbjct: 70 HAKKRLIL 77
>IPL1_YEAST (P38991) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) (Increase-in-ploidy protein 1) Length = 367 Score = 37.4 bits (85), Expect = 0.027 Identities = 28/87 (32%), Positives = 39/87 (44%), Gaps = 3/87 (3%) Frame = +1 Query: 142 KNLPLDFVKTITDQFSEQRILGTGAFGIVYKGIMPDGQIITVKKLAENSPIAR---EKAF 312 K LP F D F + LG G FG VY I K+ E I + +K F Sbjct: 91 KKLP-KFKSLSLDDFELGKKLGKGKFGKVYCVRHRSTGYICALKVMEKEEIIKYNLQKQF 149 Query: 313 ANEVQNIMALHHENVVKLVGYCHEGQK 393 EV+ +L+H N+ K GY H+ ++ Sbjct: 150 RREVEIQTSLNHPNLTKSYGYFHDEKR 176
>KPCD1_MOUSE (Q62101) Serine/threonine-protein kinase D1 (EC 2.7.11.13)| (nPKC-D1) (Protein kinase D) (Protein kinase C mu type) (nPKC-mu) Length = 918 Score = 37.4 bits (85), Expect = 0.027 Identities = 24/70 (34%), Positives = 37/70 (52%), Gaps = 2/70 (2%) Frame = +1 Query: 163 VKTITDQFSEQRILGTGAFGIVYKG-IMPDGQIITVKKLAE-NSPIAREKAFANEVQNIM 336 + T+ F ++ +LG+G FGIVY G G+ + +K + + P +E NEV + Sbjct: 583 ISTVYQIFPDE-VLGSGQFGIVYGGKHRKTGRDVAIKIIDKLRFPTKQESQLRNEVAILQ 641 Query: 337 ALHHENVVKL 366 LHH VV L Sbjct: 642 NLHHPGVVNL 651
>SEA_AVIET (P23049) Tyrosine-protein kinase transforming protein SEA (EC| 2.7.10.2) Length = 370 Score = 37.4 bits (85), Expect = 0.027 Identities = 31/114 (27%), Positives = 50/114 (43%), Gaps = 16/114 (14%) Frame = +1 Query: 85 SAMSTSAGGGQPSVL----STLPKNLPLDFVKTITDQFSEQ--------RILGTGAFGIV 228 SA + +AGGG P +L S ++L + ++ + D + R++G G FG V Sbjct: 15 SAGADAAGGGSPVLLLRTTSCCLEDLRPELLEEVKDILIPEERLITHRSRVIGRGHFGSV 74 Query: 229 YKGIMPDGQI----ITVKKLAENSPIAREKAFANEVQNIMALHHENVVKLVGYC 378 Y G D + VK L + + + F E + HH V+ L+G C Sbjct: 75 YHGTYMDPLLGNLHCAVKSLHRITYLEEVEEFLREGILMKGFHHPQVLSLLGVC 128
>ATG1_KLULA (Q6CSX2) Serine/threonine-protein kinase ATG1 (EC 2.7.11.1)| (Autophagy-related protein 1) Length = 831 Score = 37.4 bits (85), Expect = 0.027 Identities = 20/73 (27%), Positives = 43/73 (58%), Gaps = 4/73 (5%) Frame = +1 Query: 163 VKTITDQFSEQRILGTGAFGIVYKGI-MPDGQIITVKKLAENSPIAREKAFAN---EVQN 330 ++ T+ +S ++ +G G+F +VYKG+ + DG+ I +K ++ S + +K N E+ Sbjct: 14 IRLPTENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVS-RSKLKNKKLLENLEVEIAI 72 Query: 331 IMALHHENVVKLV 369 + + H ++V L+ Sbjct: 73 LKKIKHPHIVGLI 85
>ROR1_MOUSE (Q9Z139) Tyrosine-protein kinase transmembrane receptor ROR1| precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1) (mROR1) Length = 937 Score = 37.4 bits (85), Expect = 0.027 Identities = 37/119 (31%), Positives = 51/119 (42%), Gaps = 13/119 (10%) Frame = +1 Query: 55 SSSPQXLVQPSAMSTSAGGGQPSVLSTL--------PKNLPLDFVKTITDQFSEQRILGT 210 SSSP QP + GQ +S L K LPL V+ F E+ LG Sbjct: 434 SSSPPVQRQPKPVR-----GQNVEMSMLNAYKPKSKAKELPLSAVR-----FMEE--LGE 481 Query: 211 GAFGIVYKGI-----MPDGQIITVKKLAENSPIAREKAFANEVQNIMALHHENVVKLVG 372 FG +YKG M Q++ +K L + + + F E + LHH N+V L+G Sbjct: 482 CTFGKIYKGHLYLPGMDHAQLVAIKTLKDYNNPQQWTEFQQEASLMAELHHPNIVCLLG 540
>BMPR2_MOUSE (O35607) Bone morphogenetic protein receptor type-2 precursor (EC| 2.7.11.30) (Bone morphogenetic protein receptor type II) (BMP type II receptor) (BMPR-II) (BRK-3) Length = 1038 Score = 37.4 bits (85), Expect = 0.027 Identities = 31/107 (28%), Positives = 51/107 (47%), Gaps = 2/107 (1%) Frame = +1 Query: 178 DQFSEQRILGTGAFGIVYKGIMPDGQIITVKKLAENSPIAREKAFANE--VQNIMALHHE 351 D ++G G +G VYKG + D + + VK + A + F NE + + + H+ Sbjct: 201 DNLKLLELIGRGRYGAVYKGSL-DERPVAVKVFS----FANRQNFINEKNIYRVPLMEHD 255 Query: 352 NVVKLVGYCHEGQKKVVQNNGRYIVADIVESLLCHEYVPKGSLQKNL 492 N+ + + G +++ + GR +E LL EY P GSL K L Sbjct: 256 NIARFI----VGDERLTAD-GR------MEYLLVMEYYPNGSLCKYL 291
>NTRK3_PIG (P24786) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (GP145-TrkC) (Trk-C) Length = 825 Score = 37.4 bits (85), Expect = 0.027 Identities = 22/75 (29%), Positives = 38/75 (50%), Gaps = 5/75 (6%) Frame = +1 Query: 193 QRILGTGAFGIVYKG----IMPDG-QIITVKKLAENSPIAREKAFANEVQNIMALHHENV 357 +R LG GAFG V+ + P +++ K ++ +A K F E + + L HE++ Sbjct: 541 KRELGEGAFGKVFLAECYNLSPTKVKMLVAVKALKDPTLAARKDFQREAELLTNLQHEHI 600 Query: 358 VKLVGYCHEGQKKVV 402 VK G C +G ++ Sbjct: 601 VKFYGVCGDGDPLIM 615
>KPCD1_HUMAN (Q15139) Serine/threonine-protein kinase D1 (EC 2.7.11.13)| (nPKC-D1) (Protein kinase D) (Protein kinase C mu type) (nPKC-mu) Length = 912 Score = 37.4 bits (85), Expect = 0.027 Identities = 24/70 (34%), Positives = 37/70 (52%), Gaps = 2/70 (2%) Frame = +1 Query: 163 VKTITDQFSEQRILGTGAFGIVYKG-IMPDGQIITVKKLAE-NSPIAREKAFANEVQNIM 336 + T+ F ++ +LG+G FGIVY G G+ + +K + + P +E NEV + Sbjct: 577 ISTVYQIFPDE-VLGSGQFGIVYGGKHRKTGRDVAIKIIDKLRFPTKQESQLRNEVAILQ 635 Query: 337 ALHHENVVKL 366 LHH VV L Sbjct: 636 NLHHPGVVNL 645
>TYK2_HUMAN (P29597) Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)| Length = 1187 Score = 37.4 bits (85), Expect = 0.027 Identities = 29/104 (27%), Positives = 44/104 (42%), Gaps = 5/104 (4%) Frame = +1 Query: 196 RILGTGAFGIVYKGIMPD-----GQIITVKKLAENSPIAREKAFANEVQNIMALHHENVV 360 R LG G FG V G+++ VK L + + E+ + L+HE+++ Sbjct: 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 Query: 361 KLVGYCHEGQKKVVQNNGRYIVADIVESLLCHEYVPKGSLQKNL 492 K G C + +K +Q L EYVP GSL+ L Sbjct: 961 KYKGCCEDQGEKSLQ--------------LVMEYVPLGSLRDYL 990
>PHO85_CANAL (Q9HGY5) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) (CaPHO85) Length = 326 Score = 37.4 bits (85), Expect = 0.027 Identities = 21/74 (28%), Positives = 34/74 (45%), Gaps = 1/74 (1%) Frame = +1 Query: 175 TDQFSEQRILGTGAFGIVYKGI-MPDGQIITVKKLAENSPIAREKAFANEVQNIMALHHE 351 + QF + LG G + VYKG G ++ +K+++ +S E+ + L HE Sbjct: 5 SSQFQQLEKLGEGTYATVYKGRNRATGALVALKEISLDSEEGTPSTAIREISLMKELDHE 64 Query: 352 NVVKLVGYCHEGQK 393 N+V L H K Sbjct: 65 NIVTLYDVIHTENK 78
>FPS_DROME (P18106) Tyrosine-protein kinase Fps85D (EC 2.7.10.2) (dFer)| Length = 1325 Score = 37.4 bits (85), Expect = 0.027 Identities = 20/64 (31%), Positives = 33/64 (51%), Gaps = 1/64 (1%) Frame = +1 Query: 202 LGTGAFGIVYKGIMPDGQI-ITVKKLAENSPIAREKAFANEVQNIMALHHENVVKLVGYC 378 +G G FG VYK + ++ + VK P +++ F E + + H N+VKL+G C Sbjct: 1069 IGRGNFGDVYKAKLKSTKLDVAVKTCRMTLPDEQKRKFLQEGRILKQYDHPNIVKLIGIC 1128 Query: 379 HEGQ 390 + Q Sbjct: 1129 VQKQ 1132
>FAK2_RAT (P70600) Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal| adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) Length = 1009 Score = 37.4 bits (85), Expect = 0.027 Identities = 21/67 (31%), Positives = 36/67 (53%), Gaps = 4/67 (5%) Frame = +1 Query: 196 RILGTGAFGIVYKGIMPDGQ----IITVKKLAENSPIAREKAFANEVQNIMALHHENVVK 363 RILG G FG VY+G+ + + + VK ++ + ++ F +E + L H ++VK Sbjct: 429 RILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKNLDHPHIVK 488 Query: 364 LVGYCHE 384 L+G E Sbjct: 489 LIGIIEE 495
>FAK2_HUMAN (Q14289) Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal| adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinas Length = 1009 Score = 37.4 bits (85), Expect = 0.027 Identities = 21/67 (31%), Positives = 36/67 (53%), Gaps = 4/67 (5%) Frame = +1 Query: 196 RILGTGAFGIVYKGIMPDGQ----IITVKKLAENSPIAREKAFANEVQNIMALHHENVVK 363 RILG G FG VY+G+ + + + VK ++ + ++ F +E + L H ++VK Sbjct: 429 RILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKNLDHPHIVK 488 Query: 364 LVGYCHE 384 L+G E Sbjct: 489 LIGIIEE 495
>ARAF_PIG (O19004) A-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (A-Raf-1) Length = 606 Score = 37.4 bits (85), Expect = 0.027 Identities = 20/59 (33%), Positives = 35/59 (59%), Gaps = 1/59 (1%) Frame = +1 Query: 202 LGTGAFGIVYKGIMPDGQIITVKKLAENSPIARE-KAFANEVQNIMALHHENVVKLVGY 375 +GTG+FG V++G + V K+A+ P A + +AF NE+Q + H N++ +G+ Sbjct: 316 IGTGSFGTVFRGRWHGDVAVKVLKVAQ--PTAEQAQAFKNEMQVLRKTRHVNILLFMGF 372
>M3K3_ARATH (O22042) Mitogen-activated protein kinase kinase kinase 3 (EC| 2.7.11.25) (Arabidospsis NPK1-related protein kinase 3) Length = 651 Score = 37.4 bits (85), Expect = 0.027 Identities = 31/106 (29%), Positives = 51/106 (48%), Gaps = 8/106 (7%) Frame = +1 Query: 199 ILGTGAFGIVYKGI-MPDGQIITVKK-LAENSPIAREKA------FANEVQNIMALHHEN 354 ++G GAFG VY G+ + G+++ +K+ L S ++EK EVQ + L H N Sbjct: 73 LIGCGAFGRVYMGMNLDSGELLAIKQVLIAPSSASKEKTQGHIRELEEEVQLLKNLSHPN 132 Query: 355 VVKLVGYCHEGQKKVVQNNGRYIVADIVESLLCHEYVPKGSLQKNL 492 +V+ +G E +D + L+ E+VP GS+ L Sbjct: 133 IVRYLGTVRE--------------SDSLNILM--EFVPGGSISSLL 162
>STK6_XENLA (Q91820) Serine/threonine-protein kinase Eg2 (EC 2.7.11.1) (pEg2)| (p46Eg265) Length = 407 Score = 37.4 bits (85), Expect = 0.027 Identities = 44/169 (26%), Positives = 63/169 (37%), Gaps = 8/169 (4%) Frame = +1 Query: 10 PLRTARXNH----PQCWXFSSSPQXLVQPSAMSTSAGGG-QPSVLSTLPKNLPLDFVKTI 174 PLR A H PQ + +PQ S + G S +PK + Sbjct: 78 PLRPATQGHQSSKPQGPNENRNPQQTSHSSTPNVEKKGSTDQGKTSAVPKEEGKKKQWCL 137 Query: 175 TDQFSEQRILGTGAFGIVYKGIMPDGQIITVKKLAENSPIAR---EKAFANEVQNIMALH 345 D F R LG G FG VY + + I K+ S + + E EV+ L Sbjct: 138 ED-FEIGRPLGKGKFGNVYLARERESKFILALKVLFKSQLEKAGVEHQLRREVEIQSHLR 196 Query: 346 HENVVKLVGYCHEGQKKVVQNNGRYIVADIVESLLCHEYVPKGSLQKNL 492 H N+++L GY H+ + Y++ D Y P G L + L Sbjct: 197 HPNILRLYGYFHDASRV-------YLILD---------YAPGGELFREL 229
>ARAF_RAT (P14056) A-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) Length = 604 Score = 37.4 bits (85), Expect = 0.027 Identities = 20/59 (33%), Positives = 35/59 (59%), Gaps = 1/59 (1%) Frame = +1 Query: 202 LGTGAFGIVYKGIMPDGQIITVKKLAENSPIARE-KAFANEVQNIMALHHENVVKLVGY 375 +GTG+FG V++G + V K+A+ P A + +AF NE+Q + H N++ +G+ Sbjct: 314 IGTGSFGTVFRGRWHGDVAVKVLKVAQ--PTAEQAQAFKNEMQVLRKTRHVNILLFMGF 370
>ARAF_MOUSE (P04627) A-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) Length = 604 Score = 37.4 bits (85), Expect = 0.027 Identities = 20/59 (33%), Positives = 35/59 (59%), Gaps = 1/59 (1%) Frame = +1 Query: 202 LGTGAFGIVYKGIMPDGQIITVKKLAENSPIARE-KAFANEVQNIMALHHENVVKLVGY 375 +GTG+FG V++G + V K+A+ P A + +AF NE+Q + H N++ +G+ Sbjct: 314 IGTGSFGTVFRGRWHGDVAVKVLKVAQ--PTAEQAQAFKNEMQVLRKTRHVNILLFMGF 370
>CPK1_CRYNE (Q8NK05) Mitogen-activated protein kinase CPK1 (EC 2.7.11.24)| (Stress-activated protein kinase CPK1) Length = 366 Score = 37.4 bits (85), Expect = 0.027 Identities = 20/92 (21%), Positives = 45/92 (48%), Gaps = 1/92 (1%) Frame = +1 Query: 172 ITDQFSEQRILGTGAFGIVYKGI-MPDGQIITVKKLAENSPIAREKAFANEVQNIMALHH 348 + + + I+G GA+G+V G +P G + +K++ + E++ + HH Sbjct: 12 VPSTYKLEEIVGEGAYGLVVAGTHLPSGTQVAIKRITPFDHTMFCQRTLREIKLLRHFHH 71 Query: 349 ENVVKLVGYCHEGQKKVVQNNGRYIVADIVES 444 EN++ ++ +V N Y+V +++E+ Sbjct: 72 ENIISILDLIQPESYEVF--NEVYLVQELMET 101
>MOS_ATHNI (Q8QHF0) Serine/threonine-protein kinase mos (EC 2.7.11.1) (Oocyte| maturation factor mos) (Fragment) Length = 189 Score = 37.4 bits (85), Expect = 0.027 Identities = 23/59 (38%), Positives = 35/59 (59%), Gaps = 2/59 (3%) Frame = +1 Query: 199 ILGTGAFGIVYKGIMPDGQIITVKKL--AENSPIAREKAFANEVQNIMALHHENVVKLV 369 +LG+G FG VYK I G + VKK+ + +A ++F E+ N+ L H NVV++V Sbjct: 4 LLGSGGFGSVYKAIY-HGATVAVKKVKRCSKNHLASRQSFWAEL-NVARLDHNNVVRIV 60
>CDK3_HUMAN (Q00526) Cell division protein kinase 3 (EC 2.7.11.22)| Length = 305 Score = 37.4 bits (85), Expect = 0.027 Identities = 21/74 (28%), Positives = 39/74 (52%), Gaps = 2/74 (2%) Frame = +1 Query: 178 DQFSEQRILGTGAFGIVYKGIMPD-GQIITVKKLAENSPIAREKAFA-NEVQNIMALHHE 351 D F + +G G +G+VYK + GQ++ +KK+ + + + A E+ + L H Sbjct: 2 DMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKHP 61 Query: 352 NVVKLVGYCHEGQK 393 N+V+L+ H +K Sbjct: 62 NIVRLLDVVHNERK 75
>ITK_HUMAN (Q08881) Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2)| (T-cell-specific kinase) (Tyrosine-protein kinase Lyk) (Kinase EMT) Length = 620 Score = 37.0 bits (84), Expect = 0.035 Identities = 19/61 (31%), Positives = 33/61 (54%) Frame = +1 Query: 202 LGTGAFGIVYKGIMPDGQIITVKKLAENSPIAREKAFANEVQNIMALHHENVVKLVGYCH 381 +G+G FG+V+ G + + +K + E + E+ F E + +M L H +V+L G C Sbjct: 369 IGSGQFGLVHLGYWLNKDKVAIKTIREGA--MSEEDFIEEAEVMMKLSHPKLVQLYGVCL 426 Query: 382 E 384 E Sbjct: 427 E 427
>M3K10_HUMAN (Q02779) Mitogen-activated protein kinase kinase kinase 10 (EC| 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST) Length = 954 Score = 37.0 bits (84), Expect = 0.035 Identities = 29/108 (26%), Positives = 43/108 (39%), Gaps = 3/108 (2%) Frame = +1 Query: 64 PQXLVQPSAMSTSAGGGQPSVLSTLPKNLPLDFVKTITDQFSEQRILGTGAFGIVYKGIM 243 P V P A + AG LP+ +P + + I+G G FG VY+ + Sbjct: 72 PSNYVAPGAPAAPAG-------LQLPQEIPFH-------ELQLEEIIGVGGFGKVYRALW 117 Query: 244 PDGQIITVKKLA---ENSPIAREKAFANEVQNIMALHHENVVKLVGYC 378 G+ + VK E P + E + AL H N++ L G C Sbjct: 118 R-GEEVAVKAARLDPEKDPAVTAEQVCQEARLFGALQHPNIIALRGAC 164
>IGF1R_RAT (P24062) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] Length = 1370 Score = 37.0 bits (84), Expect = 0.035 Identities = 22/82 (26%), Positives = 43/82 (52%), Gaps = 7/82 (8%) Frame = +1 Query: 178 DQFSEQRILGTGAFGIVYKGIM-------PDGQIITVKKLAENSPIAREKAFANEVQNIM 336 ++ + R LG G+FG+VY+G+ P+ + + +K + E + + F NE + Sbjct: 998 EKITMNRELGQGSFGMVYEGVAKGVVKDEPETR-VAIKTVNEAASMRERIEFLNEASVMK 1056 Query: 337 ALHHENVVKLVGYCHEGQKKVV 402 + +VV+L+G +GQ +V Sbjct: 1057 EFNCHHVVRLLGVVSQGQPTLV 1078
>CDK3_MOUSE (Q80YP0) Truncated cell division protein kinase 3 homolog| Length = 186 Score = 37.0 bits (84), Expect = 0.035 Identities = 23/78 (29%), Positives = 37/78 (47%), Gaps = 6/78 (7%) Frame = +1 Query: 178 DQFSEQRILGTGAFGIVYKG-IMPDGQIITVKKL-----AENSPIAREKAFANEVQNIMA 339 D F + +G G +G+VYK GQ++ +KK+ AE P E+ + Sbjct: 2 DVFQKVEKIGEGTYGVVYKARNKVTGQLVALKKIRLDLEAEGVP----STAVREISLLKE 57 Query: 340 LHHENVVKLVGYCHEGQK 393 L H N++KL+ H +K Sbjct: 58 LKHPNIIKLLDVVHREKK 75
>MAPK_FUSSO (Q00859) Mitogen-activated protein kinase (EC 2.7.11.24) (FsMAPK)| Length = 355 Score = 37.0 bits (84), Expect = 0.035 Identities = 20/92 (21%), Positives = 47/92 (51%), Gaps = 1/92 (1%) Frame = +1 Query: 172 ITDQFSEQRILGTGAFGIVYKGI-MPDGQIITVKKLAENSPIAREKAFANEVQNIMALHH 348 +++Q+ Q ++G GA+G+V I P GQ + +KK+ E++ + +H Sbjct: 19 VSEQYDIQDVVGEGAYGVVCSAIHKPSGQKVAIKKITPFDHSMFCLRTLREMKLLRYFNH 78 Query: 349 ENVVKLVGYCHEGQKKVVQNNGRYIVADIVES 444 EN++ ++ + + N Y++ +++E+ Sbjct: 79 ENIISILDI--QKPRNYESFNEVYLIQELMET 108
>INSR_MOUSE (P15208) Insulin receptor precursor (EC 2.7.10.1) (IR) [Contains:| Insulin receptor alpha subunit; Insulin receptor beta subunit] Length = 1372 Score = 37.0 bits (84), Expect = 0.035 Identities = 24/75 (32%), Positives = 39/75 (52%), Gaps = 6/75 (8%) Frame = +1 Query: 196 RILGTGAFGIVYKGIMPD---GQI---ITVKKLAENSPIAREKAFANEVQNIMALHHENV 357 R LG G+FG+VY+G D G+ + VK + E++ + F NE + +V Sbjct: 1017 RELGQGSFGMVYEGNAKDIIKGEAETRVAVKTVNESASLRERIEFLNEASVMKGFTCHHV 1076 Query: 358 VKLVGYCHEGQKKVV 402 V+L+G +GQ +V Sbjct: 1077 VRLLGVVSKGQPMLV 1091
>MSK3_MEDSA (P51139) Glycogen synthase kinase-3 homolog MsK-3 (EC 2.7.11.1)| Length = 411 Score = 37.0 bits (84), Expect = 0.035 Identities = 20/66 (30%), Positives = 38/66 (57%), Gaps = 2/66 (3%) Frame = +1 Query: 175 TDQFSEQRILGTGAFGIVYKG-IMPDGQIITVKKLAENSPIAREKAFAN-EVQNIMALHH 348 T + +R++G G+FG+V++ + G+ + +KK + ++K + N E+Q + L H Sbjct: 71 TISYMAERVVGHGSFGVVFQAKCLETGETVAIKK------VLQDKRYKNRELQTMRLLDH 124 Query: 349 ENVVKL 366 NVV L Sbjct: 125 PNVVSL 130
>MSK1_MEDSA (P51137) Glycogen synthase kinase-3 homolog MsK-1 (EC 2.7.11.1)| Length = 411 Score = 37.0 bits (84), Expect = 0.035 Identities = 20/66 (30%), Positives = 38/66 (57%), Gaps = 2/66 (3%) Frame = +1 Query: 175 TDQFSEQRILGTGAFGIVYKG-IMPDGQIITVKKLAENSPIAREKAFAN-EVQNIMALHH 348 T + +R++G G+FG+V++ + G+ + +KK + ++K + N E+Q + L H Sbjct: 72 TISYMAERVVGHGSFGVVFQAKCLETGETVAIKK------VLQDKRYKNRELQTMRLLDH 125 Query: 349 ENVVKL 366 NVV L Sbjct: 126 PNVVSL 131
>IGF1R_MOUSE (Q60751) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] Length = 1373 Score = 37.0 bits (84), Expect = 0.035 Identities = 22/82 (26%), Positives = 43/82 (52%), Gaps = 7/82 (8%) Frame = +1 Query: 178 DQFSEQRILGTGAFGIVYKGIM-------PDGQIITVKKLAENSPIAREKAFANEVQNIM 336 ++ + R LG G+FG+VY+G+ P+ + + +K + E + + F NE + Sbjct: 998 EKITMNRELGQGSFGMVYEGVAKGVVKDEPETR-VAIKTVNEAASMRERIEFLNEASVMK 1056 Query: 337 ALHHENVVKLVGYCHEGQKKVV 402 + +VV+L+G +GQ +V Sbjct: 1057 EFNCHHVVRLLGVVSQGQPTLV 1078
>IGF1R_BOVIN (Q05688) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] (F Length = 640 Score = 37.0 bits (84), Expect = 0.035 Identities = 22/82 (26%), Positives = 43/82 (52%), Gaps = 7/82 (8%) Frame = +1 Query: 178 DQFSEQRILGTGAFGIVYKGIM-------PDGQIITVKKLAENSPIAREKAFANEVQNIM 336 ++ + R LG G+FG+VY+G+ P+ + + +K + E + + F NE + Sbjct: 270 EKITMSRELGQGSFGMVYEGVAKGVVKDEPETR-VAIKTVNEAASMRERIEFLNEASVMK 328 Query: 337 ALHHENVVKLVGYCHEGQKKVV 402 + +VV+L+G +GQ +V Sbjct: 329 EFNCHHVVRLLGVVSQGQPTLV 350
>CDK2_XENLA (P23437) Cell division protein kinase 2 (EC 2.7.11.22) (CDC2| homolog Eg1 protein kinase) Length = 297 Score = 37.0 bits (84), Expect = 0.035 Identities = 21/74 (28%), Positives = 39/74 (52%), Gaps = 2/74 (2%) Frame = +1 Query: 178 DQFSEQRILGTGAFGIVYKGIMPD-GQIITVKKLAENSPIAREKAFA-NEVQNIMALHHE 351 + F + +G G +G+VYK + G+I+ +KK+ ++ + A E+ + L+H Sbjct: 2 ENFQKVEKIGEGTYGVVYKARNRETGEIVALKKIRLDTETEGVPSTAIREISLLKELNHP 61 Query: 352 NVVKLVGYCHEGQK 393 N+VKL+ H K Sbjct: 62 NIVKLLDVIHTENK 75
>CDC7_SCHPO (P41892) Cell division control protein 7 (EC 2.7.11.1)| Length = 1062 Score = 37.0 bits (84), Expect = 0.035 Identities = 26/94 (27%), Positives = 43/94 (45%), Gaps = 15/94 (15%) Frame = +1 Query: 202 LGTGAFGIVYKGI-MPDGQIITVKKLAENSPIARE-KAFANEVQNIMALHHENVVKLVG- 372 LG GAFG VY+G+ + +G+ + VKK+ + + + E+ + L H N+VK G Sbjct: 15 LGKGAFGAVYRGLNIKNGETVAVKKVKLSKMLKSDLSVIKMEIDLLKNLDHPNIVKYRGS 74 Query: 373 ------------YCHEGQKKVVQNNGRYIVADIV 438 YC G + + N I ++V Sbjct: 75 YQTNDSLCIILEYCENGSLRSICKNFGKIPENLV 108
>TNK1_HUMAN (Q13470) Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2)| (CD38 negative kinase 1) Length = 666 Score = 37.0 bits (84), Expect = 0.035 Identities = 28/97 (28%), Positives = 53/97 (54%), Gaps = 11/97 (11%) Frame = +1 Query: 115 QPSVLSTLPKNLPLDF--VKTITDQFSEQR--ILGTGAFGIVYKGI--MPDGQIITVK-- 270 +P++ S P++LP +K + + + R +LG+G FG+V++G+ +P G+ + V Sbjct: 89 EPTLPSDSPRHLPEPEGGLKCLIPEGAVCRGELLGSGCFGVVHRGLWTLPSGKSVPVAVK 148 Query: 271 --KLAENSPIAREKA-FANEVQNIMALHHENVVKLVG 372 ++ P+ E F EV +M L H +V++L G Sbjct: 149 SLRVGPEGPMGTELGDFLREVSVMMNLEHPHVLRLHG 185
>M3K1_ARATH (O22040) Mitogen-activated protein kinase kinase kinase 1 (EC| 2.7.11.25) (Arabidospsis NPK1-related protein kinase 1) Length = 666 Score = 37.0 bits (84), Expect = 0.035 Identities = 32/107 (29%), Positives = 53/107 (49%), Gaps = 8/107 (7%) Frame = +1 Query: 196 RILGTGAFGIVYKGI-MPDGQIITVKKLAENSPIA-REKAFAN------EVQNIMALHHE 351 +++G GAFG VY G+ + G+++ VK++ + A +EK A+ EV+ + L H Sbjct: 73 QLIGRGAFGTVYMGMNLDSGELLAVKQVLIAANFASKEKTQAHIQELEEEVKLLKNLSHP 132 Query: 352 NVVKLVGYCHEGQKKVVQNNGRYIVADIVESLLCHEYVPKGSLQKNL 492 N+V+ +G E D + LL E+VP GS+ L Sbjct: 133 NIVRYLGTVRED--------------DTLNILL--EFVPGGSISSLL 163
>ARAF_HUMAN (P10398) A-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (A-raf-1) (Proto-oncogene Pks) Length = 606 Score = 37.0 bits (84), Expect = 0.035 Identities = 20/59 (33%), Positives = 34/59 (57%), Gaps = 1/59 (1%) Frame = +1 Query: 202 LGTGAFGIVYKGIMPDGQIITVKKLAENSPIARE-KAFANEVQNIMALHHENVVKLVGY 375 +GTG+FG V++G + VK L + P A + +AF NE+Q + H N++ +G+ Sbjct: 316 IGTGSFGTVFRGRWHGD--VAVKVLKVSQPTAEQAQAFKNEMQVLRKTRHVNILLFMGF 372
>IGF1R_HUMAN (P08069) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 recepto Length = 1367 Score = 37.0 bits (84), Expect = 0.035 Identities = 22/82 (26%), Positives = 43/82 (52%), Gaps = 7/82 (8%) Frame = +1 Query: 178 DQFSEQRILGTGAFGIVYKGIM-------PDGQIITVKKLAENSPIAREKAFANEVQNIM 336 ++ + R LG G+FG+VY+G+ P+ + + +K + E + + F NE + Sbjct: 997 EKITMSRELGQGSFGMVYEGVAKGVVKDEPETR-VAIKTVNEAASMRERIEFLNEASVMK 1055 Query: 337 ALHHENVVKLVGYCHEGQKKVV 402 + +VV+L+G +GQ +V Sbjct: 1056 EFNCHHVVRLLGVVSQGQPTLV 1077
>PHO85_CANGA (Q6FKD4) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 302 Score = 37.0 bits (84), Expect = 0.035 Identities = 20/74 (27%), Positives = 34/74 (45%), Gaps = 1/74 (1%) Frame = +1 Query: 175 TDQFSEQRILGTGAFGIVYKGI-MPDGQIITVKKLAENSPIAREKAFANEVQNIMALHHE 351 + QF + LG G + VYKG+ G + +K++ +S E+ + L H+ Sbjct: 3 SSQFKQLEKLGNGTYATVYKGLNKSTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHD 62 Query: 352 NVVKLVGYCHEGQK 393 N+V+L H K Sbjct: 63 NIVRLYDVIHTENK 76
>ITK_MOUSE (Q03526) Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2)| (T-cell-specific kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (Kinase TLK) Length = 625 Score = 37.0 bits (84), Expect = 0.035 Identities = 19/61 (31%), Positives = 33/61 (54%) Frame = +1 Query: 202 LGTGAFGIVYKGIMPDGQIITVKKLAENSPIAREKAFANEVQNIMALHHENVVKLVGYCH 381 +G+G FG+V+ G + + +K + E + E+ F E + +M L H +V+L G C Sbjct: 374 IGSGQFGLVHLGYWLNKDKVAIKTIQEGA--MSEEDFIEEAEVMMKLSHPKLVQLYGVCL 431 Query: 382 E 384 E Sbjct: 432 E 432
>CDC22_XENLA (P24033) Cell division control protein 2 homolog 2 (EC 2.7.11.22)| (EC 2.7.11.23) (p34 protein kinase 2) Length = 302 Score = 37.0 bits (84), Expect = 0.035 Identities = 20/66 (30%), Positives = 35/66 (53%), Gaps = 2/66 (3%) Frame = +1 Query: 178 DQFSEQRILGTGAFGIVYKG-IMPDGQIITVKKL-AENSPIAREKAFANEVQNIMALHHE 351 D++++ +G G +G+VYKG GQ++ +KK+ EN E+ + L H Sbjct: 2 DEYTKIEKIGEGTYGVVYKGRHKATGQVVAMKKIRLENEEEGVPSTAIREISLLKELQHP 61 Query: 352 NVVKLV 369 N+V L+ Sbjct: 62 NIVCLL 67
>CDC21_XENLA (P35567) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| (EC 2.7.11.23) (p34 protein kinase 1) Length = 302 Score = 37.0 bits (84), Expect = 0.035 Identities = 20/66 (30%), Positives = 35/66 (53%), Gaps = 2/66 (3%) Frame = +1 Query: 178 DQFSEQRILGTGAFGIVYKG-IMPDGQIITVKKL-AENSPIAREKAFANEVQNIMALHHE 351 D++++ +G G +G+VYKG GQ++ +KK+ EN E+ + L H Sbjct: 2 DEYTKIEKIGEGTYGVVYKGRHKATGQVVAMKKIRLENEEEGVPSTAIREISLLKELQHP 61 Query: 352 NVVKLV 369 N+V L+ Sbjct: 62 NIVCLL 67
>VGFR1_RAT (P53767) Vascular endothelial growth factor receptor 1 precursor (EC| 2.7.10.1) (VEGFR-1) (Tyrosine-protein kinase receptor FLT) (FLT-1) Length = 1336 Score = 36.6 bits (83), Expect = 0.045 Identities = 31/91 (34%), Positives = 46/91 (50%), Gaps = 12/91 (13%) Frame = +1 Query: 142 KNLPLDFVKTITDQFSEQRI-----LGTGAFGIVYK----GIM--PDGQIITVKKLAENS 288 + LP D K +F+ +R+ LG GAFG V + GI P + + VK L E + Sbjct: 811 ERLPYDASKW---EFARERLKLGKSLGRGAFGKVVQASAFGIKKSPTCRTVAVKMLKEGA 867 Query: 289 PIAREKAFANEVQNIMAL-HHENVVKLVGYC 378 + KA E++ + + HH NVV L+G C Sbjct: 868 TASEYKALMTELKILTHIGHHLNVVNLLGAC 898
>7LESS_DROVI (P20806) Protein sevenless (EC 2.7.10.1)| Length = 2594 Score = 36.6 bits (83), Expect = 0.045 Identities = 23/66 (34%), Positives = 33/66 (50%), Gaps = 5/66 (7%) Frame = +1 Query: 196 RILGTGAFGIVYKGIM-----PDGQIITVKKLAENSPIAREKAFANEVQNIMALHHENVV 360 R LG+GAFG VY+G + Q + +K L + + E E Q + HEN+V Sbjct: 2228 RFLGSGAFGEVYEGQLQAEDEAQPQRVAIKSLRKGASEFAE--LLQEAQLMSNFKHENIV 2285 Query: 361 KLVGYC 378 L+G C Sbjct: 2286 CLIGIC 2291
>TESK2_RAT (Q924U5) Dual specificity testis-specific protein kinase 2 (EC| 2.7.12.1) (Testicular protein kinase 2) Length = 570 Score = 36.6 bits (83), Expect = 0.045 Identities = 31/124 (25%), Positives = 57/124 (45%), Gaps = 2/124 (1%) Frame = +1 Query: 169 TITDQFSEQRILGTGAFGIVYK-GIMPDGQIITVKKLAENSPIAREKAFANEVQNIMALH 345 T D F+ ++I G+G F V+K GQ++ +K N+ + E+Q + L Sbjct: 54 TSLDDFTREKI-GSGFFSEVFKVRHRASGQVMALKM---NTLSSNRANLLKEMQLMNRLS 109 Query: 346 HENVVKLVGYC-HEGQKKVVQNNGRYIVADIVESLLCHEYVPKGSLQKNLFEVDTKMDWS 522 H N+++ +G C H+GQ + EY+ G+L++ L + + + W+ Sbjct: 110 HPNILRFMGVCVHQGQLHALT-----------------EYINSGNLEQ-LLDSNLYLPWT 151 Query: 523 TRFK 534 R K Sbjct: 152 VRVK 155
>MUSK_CHICK (Q8AXY6) Muscle, skeletal receptor tyrosine protein kinase| precursor (EC 2.7.10.1) (Muscle-specific tyrosine protein kinase receptor) (Muscle-specific kinase receptor) (MuSK) Length = 947 Score = 36.6 bits (83), Expect = 0.045 Identities = 26/90 (28%), Positives = 44/90 (48%), Gaps = 6/90 (6%) Frame = +1 Query: 139 PKNLPLDFVKTITDQFSEQRILGTGAFGIVYK----GIMP--DGQIITVKKLAENSPIAR 300 PK L L++ + + R +G GAFG V++ G++P ++ VK L E + Sbjct: 643 PKLLSLEYPR---NNIEYVRDIGEGAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADM 699 Query: 301 EKAFANEVQNIMALHHENVVKLVGYCHEGQ 390 + F E + + N+VKL+G C G+ Sbjct: 700 QADFQREAALMAEFDNPNIVKLLGVCAVGK 729
>KSG6_ARATH (Q39010) Shaggy-related protein kinase dzeta (EC 2.7.11.1)| (ASK-dzeta) Length = 412 Score = 36.6 bits (83), Expect = 0.045 Identities = 20/66 (30%), Positives = 39/66 (59%), Gaps = 2/66 (3%) Frame = +1 Query: 175 TDQFSEQRILGTGAFGIVYKG-IMPDGQIITVKKLAENSPIAREKAFAN-EVQNIMALHH 348 T + +R++GTG+FGIV++ + G+ + +KK + +++ + N E+Q + + H Sbjct: 69 TISYMAERVVGTGSFGIVFQAKCLETGESVAIKK------VLQDRRYKNRELQLMRLMDH 122 Query: 349 ENVVKL 366 NVV L Sbjct: 123 PNVVSL 128
>RYK_AVIR3 (P33497) Tyrosine-protein kinase transforming protein RYK (EC| 2.7.10.1) Length = 442 Score = 36.6 bits (83), Expect = 0.045 Identities = 25/68 (36%), Positives = 38/68 (55%), Gaps = 5/68 (7%) Frame = +1 Query: 196 RILGTGAFGIVYKGIM--PDG--QIITVKKLAENSPIARE-KAFANEVQNIMALHHENVV 360 ++LG G FG V +G + P+G Q + VK + ++ RE + F +E I H NV+ Sbjct: 49 KVLGEGEFGSVMEGRLSQPEGTPQKVAVKTMKLDNFSHREIEEFLSEAACIKDFDHPNVI 108 Query: 361 KLVGYCHE 384 KL+G C E Sbjct: 109 KLLGVCIE 116
>CDPK2_PLAFK (O15865) Calcium-dependent protein kinase 2 (EC 2.7.11.1) (PfCDPK2)| Length = 512 Score = 36.6 bits (83), Expect = 0.045 Identities = 23/75 (30%), Positives = 34/75 (45%) Frame = +1 Query: 142 KNLPLDFVKTITDQFSEQRILGTGAFGIVYKGIMPDGQIITVKKLAENSPIAREKAFANE 321 KNL L + D++ LG G +G VYKGI + K + + F E Sbjct: 57 KNLILCHSGKLEDKYIIDEKLGQGTYGCVYKGIDKVTNQLYAIKEEKKDRLKNINRFFQE 116 Query: 322 VQNIMALHHENVVKL 366 ++ + L H N+VKL Sbjct: 117 IEIMKKLDHPNIVKL 131
>VGFR1_MOUSE (P35969) Vascular endothelial growth factor receptor 1 precursor (EC| 2.7.10.1) (VEGFR-1) (Tyrosine-protein kinase receptor FLT) (FLT-1) (Embryonic receptor kinase 2) Length = 1333 Score = 36.6 bits (83), Expect = 0.045 Identities = 31/91 (34%), Positives = 46/91 (50%), Gaps = 12/91 (13%) Frame = +1 Query: 142 KNLPLDFVKTITDQFSEQRI-----LGTGAFGIVYK----GIM--PDGQIITVKKLAENS 288 + LP D K +F+ +R+ LG GAFG V + GI P + + VK L E + Sbjct: 812 ERLPYDASKW---EFARERLKLGKSLGRGAFGKVVQASAFGIKKSPTCRTVAVKMLKEGA 868 Query: 289 PIAREKAFANEVQNIMAL-HHENVVKLVGYC 378 + KA E++ + + HH NVV L+G C Sbjct: 869 TASEYKALMTELKILTHIGHHLNVVNLLGAC 899
>VGFR1_HUMAN (P17948) Vascular endothelial growth factor receptor 1 precursor (EC| 2.7.10.1) (VEGFR-1) (Vascular permeability factor receptor) (Tyrosine-protein kinase receptor FLT) (Flt-1) (Tyrosine-protein kinase FRT) (Fms-like tyrosine kinase 1) Length = 1338 Score = 36.6 bits (83), Expect = 0.045 Identities = 31/91 (34%), Positives = 46/91 (50%), Gaps = 12/91 (13%) Frame = +1 Query: 142 KNLPLDFVKTITDQFSEQRI-----LGTGAFGIVYK----GIM--PDGQIITVKKLAENS 288 + LP D K +F+ +R+ LG GAFG V + GI P + + VK L E + Sbjct: 811 ERLPYDASKW---EFARERLKLGKSLGRGAFGKVVQASAFGIKKSPTCRTVAVKMLKEGA 867 Query: 289 PIAREKAFANEVQNIMAL-HHENVVKLVGYC 378 + KA E++ + + HH NVV L+G C Sbjct: 868 TASEYKALMTELKILTHIGHHLNVVNLLGAC 898
>STK6_MOUSE (P97477) Serine/threonine-protein kinase 6 (EC 2.7.11.1)| (Aurora-family kinase 1) (Aurora/IPL1-related kinase 1) (Ipl1- and aurora-related kinase 1) (Aurora-A) (Serine/threonine-protein kinase Ayk1) Length = 395 Score = 36.6 bits (83), Expect = 0.045 Identities = 36/148 (24%), Positives = 56/148 (37%), Gaps = 3/148 (2%) Frame = +1 Query: 58 SSPQXLVQPSAMSTSAGGGQPSVLSTLPKNLPLDFVKTITDQFSEQRILGTGAFGIVYKG 237 ++PQ QP+A +G ++L K + + F R LG G FG VY Sbjct: 86 NNPQKNEQPAA----SGNDSEKEQASLQKTEDTKKRQWTLEDFDIGRPLGKGKFGNVYLA 141 Query: 238 IMPDGQIITVKKLAENSPIAR---EKAFANEVQNIMALHHENVVKLVGYCHEGQKKVVQN 408 + I K+ + + + E EV+ L H N+++L GY H Sbjct: 142 RERQSKFILALKVLFKTQLEKANVEHQLRREVEIQSHLRHPNILRLYGYFH--------- 192 Query: 409 NGRYIVADIVESLLCHEYVPKGSLQKNL 492 D L EY P G++ + L Sbjct: 193 -------DATRVYLILEYAPLGTVYREL 213
>MUSK_RAT (Q62838) Muscle, skeletal receptor tyrosine protein kinase| precursor (EC 2.7.10.1) (Muscle-specific kinase receptor) (MuSK) Length = 868 Score = 36.6 bits (83), Expect = 0.045 Identities = 26/90 (28%), Positives = 44/90 (48%), Gaps = 6/90 (6%) Frame = +1 Query: 139 PKNLPLDFVKTITDQFSEQRILGTGAFGIVYK----GIMP--DGQIITVKKLAENSPIAR 300 PK L L++ + + R +G GAFG V++ G++P ++ VK L E + Sbjct: 562 PKLLSLEYPR---NNIEYVRDIGEGAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADM 618 Query: 301 EKAFANEVQNIMALHHENVVKLVGYCHEGQ 390 + F E + + N+VKL+G C G+ Sbjct: 619 QADFQREAALMAEFDNPNIVKLLGVCAVGK 648
>MUSK_MOUSE (Q61006) Muscle, skeletal receptor tyrosine protein kinase| precursor (EC 2.7.10.1) (Muscle-specific kinase receptor) (MuSK) Length = 868 Score = 36.6 bits (83), Expect = 0.045 Identities = 26/90 (28%), Positives = 44/90 (48%), Gaps = 6/90 (6%) Frame = +1 Query: 139 PKNLPLDFVKTITDQFSEQRILGTGAFGIVYK----GIMP--DGQIITVKKLAENSPIAR 300 PK L L++ + + R +G GAFG V++ G++P ++ VK L E + Sbjct: 562 PKLLSLEYPR---NNIEYVRDIGEGAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADM 618 Query: 301 EKAFANEVQNIMALHHENVVKLVGYCHEGQ 390 + F E + + N+VKL+G C G+ Sbjct: 619 QADFQREAALMAEFDNPNIVKLLGVCAVGK 648
>JAK1_BRARE (O12990) Tyrosine-protein kinase Jak1 (EC 2.7.10.2) (Janus kinase 1)| (Jak-1) Length = 1153 Score = 36.6 bits (83), Expect = 0.045 Identities = 24/81 (29%), Positives = 38/81 (46%) Frame = +1 Query: 250 GQIITVKKLAENSPIAREKAFANEVQNIMALHHENVVKLVGYCHEGQKKVVQNNGRYIVA 429 G+++ VK L + + E+ + L+HEN+VK G C+E GR I Sbjct: 899 GELVAVKSLKPENREEQSNNLWREIHILRELYHENIVKYKGICNE-------EGGRSI-- 949 Query: 430 DIVESLLCHEYVPKGSLQKNL 492 L E++P GSL++ L Sbjct: 950 -----KLIMEFLPAGSLKEYL 965
>LIMK1_RAT (P53669) LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1)| Length = 647 Score = 36.6 bits (83), Expect = 0.045 Identities = 27/111 (24%), Positives = 52/111 (46%), Gaps = 1/111 (0%) Frame = +1 Query: 199 ILGTGAFGIVYKGIMPD-GQIITVKKLAENSPIAREKAFANEVQNIMALHHENVVKLVGY 375 +LG G FG K + G+++ +K+L ++ F EV+ + L H NV+K +G Sbjct: 344 VLGKGCFGQAIKVTHRETGEVMVMKELIRFDE-ETQRTFLKEVKVMRCLEHPNVLKFIGV 402 Query: 376 CHEGQKKVVQNNGRYIVADIVESLLCHEYVPKGSLQKNLFEVDTKMDWSTR 528 ++ ++ +I EY+ G+L+ + +D++ WS R Sbjct: 403 LYKDKRL------NFIT----------EYIKGGTLRGIIKSMDSQYPWSQR 437
>LIMK1_MOUSE (P53668) LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1) (KIZ-1)| Length = 647 Score = 36.6 bits (83), Expect = 0.045 Identities = 27/111 (24%), Positives = 52/111 (46%), Gaps = 1/111 (0%) Frame = +1 Query: 199 ILGTGAFGIVYKGIMPD-GQIITVKKLAENSPIAREKAFANEVQNIMALHHENVVKLVGY 375 +LG G FG K + G+++ +K+L ++ F EV+ + L H NV+K +G Sbjct: 344 VLGKGCFGQAIKVTHRETGEVMVMKELIRFDE-ETQRTFLKEVKVMRCLEHPNVLKFIGV 402 Query: 376 CHEGQKKVVQNNGRYIVADIVESLLCHEYVPKGSLQKNLFEVDTKMDWSTR 528 ++ ++ +I EY+ G+L+ + +D++ WS R Sbjct: 403 LYKDKRL------NFIT----------EYIKGGTLRGIIKNMDSQYPWSQR 437
>LIMK1_HUMAN (P53667) LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1)| Length = 647 Score = 36.6 bits (83), Expect = 0.045 Identities = 27/111 (24%), Positives = 52/111 (46%), Gaps = 1/111 (0%) Frame = +1 Query: 199 ILGTGAFGIVYKGIMPD-GQIITVKKLAENSPIAREKAFANEVQNIMALHHENVVKLVGY 375 +LG G FG K + G+++ +K+L ++ F EV+ + L H NV+K +G Sbjct: 344 VLGKGCFGQAIKVTHRETGEVMVMKELIRFDE-ETQRTFLKEVKVMRCLEHPNVLKFIGV 402 Query: 376 CHEGQKKVVQNNGRYIVADIVESLLCHEYVPKGSLQKNLFEVDTKMDWSTR 528 ++ ++ +I EY+ G+L+ + +D++ WS R Sbjct: 403 LYKDKRL------NFIT----------EYIKGGTLRGIIKSMDSQYPWSQR 437
>JNK1_ANCCA (Q9U6D2) Stress-activated protein kinase JNK-1 (EC 2.7.11.24)| Length = 376 Score = 36.6 bits (83), Expect = 0.045 Identities = 25/96 (26%), Positives = 50/96 (52%), Gaps = 2/96 (2%) Frame = +1 Query: 172 ITDQFSEQRILGTGAFGIVYKGI-MPDGQIITVKKLAEN-SPIAREKAFANEVQNIMALH 345 I ++ R++G+GA GIV M + + +KKL+ + K E + ++ Sbjct: 22 ILKRYENLRLIGSGAQGIVCAATDMVTNKPVAIKKLSRPFQNVTHAKRAYREFILMNLVN 81 Query: 346 HENVVKLVGYCHEGQKKVVQNNGRYIVADIVESLLC 453 H+N++ L+ Q++V + N YIV +++++ LC Sbjct: 82 HKNIIGLLN-AFSPQREVEEFNDLYIVMELMDANLC 116
>IGF1R_XENLA (O73798) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (xIGF-1R) (xIGFR) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] Length = 1358 Score = 36.6 bits (83), Expect = 0.045 Identities = 23/81 (28%), Positives = 42/81 (51%), Gaps = 6/81 (7%) Frame = +1 Query: 178 DQFSEQRILGTGAFGIVY----KGIMPD--GQIITVKKLAENSPIAREKAFANEVQNIMA 339 ++ + R LG G+FG+VY KG++ D + +K + E + + F NE + Sbjct: 993 EKITMNRELGQGSFGMVYEGIAKGVVKDEAETKVAIKTVNEAASMRERIEFLNEASVMKE 1052 Query: 340 LHHENVVKLVGYCHEGQKKVV 402 + +VV+L+G +GQ +V Sbjct: 1053 FNCHHVVRLLGVVSQGQPTLV 1073
>MSK1_TOBAC (Q40518) Shaggy-related protein kinase NtK-1 (EC 2.7.11.1)| Length = 409 Score = 36.6 bits (83), Expect = 0.045 Identities = 21/66 (31%), Positives = 38/66 (57%), Gaps = 2/66 (3%) Frame = +1 Query: 175 TDQFSEQRILGTGAFGIVYKG-IMPDGQIITVKKLAENSPIAREKAFAN-EVQNIMALHH 348 T + +RI+G G+FG+V++ + G+ + +KK + ++K + N E+Q + L H Sbjct: 70 TISYMAERIVGQGSFGVVFQAKCLETGETVAIKK------VLQDKRYKNRELQTMRLLDH 123 Query: 349 ENVVKL 366 NVV L Sbjct: 124 PNVVCL 129
>GSK3A_RAT (P18265) Glycogen synthase kinase-3 alpha (EC 2.7.11.26) (GSK-3| alpha) (Factor A) (FA) Length = 483 Score = 36.6 bits (83), Expect = 0.045 Identities = 21/74 (28%), Positives = 46/74 (62%), Gaps = 3/74 (4%) Frame = +1 Query: 184 FSEQRILGTGAFGIVYKGIMPD-GQIITVKKLAENSPIAREKAFAN-EVQNIMALHHENV 357 +++ +++G G+FG+VY+ + + +++ +KK + ++K F N E+Q + L H N+ Sbjct: 119 YTDIKVIGNGSFGVVYQARLAETRELVAIKK------VLQDKRFKNRELQIMRKLDHCNI 172 Query: 358 VKLVGYCH-EGQKK 396 V+L + + G+KK Sbjct: 173 VRLRYFFYSSGEKK 186
>GSK3A_HUMAN (P49840) Glycogen synthase kinase-3 alpha (EC 2.7.11.26) (GSK-3| alpha) Length = 483 Score = 36.6 bits (83), Expect = 0.045 Identities = 21/74 (28%), Positives = 46/74 (62%), Gaps = 3/74 (4%) Frame = +1 Query: 184 FSEQRILGTGAFGIVYKGIMPD-GQIITVKKLAENSPIAREKAFAN-EVQNIMALHHENV 357 +++ +++G G+FG+VY+ + + +++ +KK + ++K F N E+Q + L H N+ Sbjct: 119 YTDIKVIGNGSFGVVYQARLAETRELVAIKK------VLQDKRFKNRELQIMRKLDHCNI 172 Query: 358 VKLVGYCH-EGQKK 396 V+L + + G+KK Sbjct: 173 VRLRYFFYSSGEKK 186
>MUSK_HUMAN (O15146) Muscle, skeletal receptor tyrosine protein kinase| precursor (EC 2.7.10.1) (Muscle-specific tyrosine protein kinase receptor) (Muscle-specific kinase receptor) (MuSK) Length = 869 Score = 36.6 bits (83), Expect = 0.045 Identities = 26/90 (28%), Positives = 44/90 (48%), Gaps = 6/90 (6%) Frame = +1 Query: 139 PKNLPLDFVKTITDQFSEQRILGTGAFGIVYK----GIMP--DGQIITVKKLAENSPIAR 300 PK L L++ + + R +G GAFG V++ G++P ++ VK L E + Sbjct: 563 PKLLSLEYPR---NNIEYVRDIGEGAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADM 619 Query: 301 EKAFANEVQNIMALHHENVVKLVGYCHEGQ 390 + F E + + N+VKL+G C G+ Sbjct: 620 QADFQREAALMAEFDNPNIVKLLGVCAVGK 649
>INSR_AEDAE (Q93105) Insulin-like receptor precursor (EC 2.7.10.1) (MIR)| [Contains: Insulin-like receptor alpha chain; Insulin-like receptor beta chain] Length = 1390 Score = 36.6 bits (83), Expect = 0.045 Identities = 21/73 (28%), Positives = 37/73 (50%), Gaps = 6/73 (8%) Frame = +1 Query: 202 LGTGAFGIVYKGIMPD------GQIITVKKLAENSPIAREKAFANEVQNIMALHHENVVK 363 LG G+FG+VYKGI+ Q +K + E++ + +F E + + +VV+ Sbjct: 1031 LGQGSFGMVYKGILTQLRGEKCNQPCAIKTVNESATAREKDSFLLEASVMKQFNTHHVVR 1090 Query: 364 LVGYCHEGQKKVV 402 L+G +G +V Sbjct: 1091 LLGVVSQGDPTLV 1103
>CDPK2_PLAF7 (Q8ICR0) Calcium-dependent protein kinase 2 (EC 2.7.11.1) (PfCDPK2)| Length = 508 Score = 36.6 bits (83), Expect = 0.045 Identities = 23/75 (30%), Positives = 34/75 (45%) Frame = +1 Query: 142 KNLPLDFVKTITDQFSEQRILGTGAFGIVYKGIMPDGQIITVKKLAENSPIAREKAFANE 321 KNL L + D++ LG G +G VYKGI + K + + F E Sbjct: 57 KNLILCHSGKLEDKYIIDEKLGQGTYGCVYKGIDKVTNQLYAIKEEKKDRLKNINRFFQE 116 Query: 322 VQNIMALHHENVVKL 366 ++ + L H N+VKL Sbjct: 117 IEIMKKLDHPNIVKL 131
>STK6L_XENLA (Q91819) Serine/threonine-protein kinase Eg2-like (EC 2.7.11.1)| (p46XlEg22) Length = 408 Score = 36.6 bits (83), Expect = 0.045 Identities = 29/108 (26%), Positives = 44/108 (40%), Gaps = 3/108 (2%) Frame = +1 Query: 178 DQFSEQRILGTGAFGIVYKGIMPDGQIITVKKLAENSPIAR---EKAFANEVQNIMALHH 348 + F R LG G FG VY + + I K+ S + + E EV+ L H Sbjct: 138 EDFEIGRPLGKGKFGNVYLARERESKFILALKVLFKSQLEKAGVEHQLRREVEIQSHLRH 197 Query: 349 ENVVKLVGYCHEGQKKVVQNNGRYIVADIVESLLCHEYVPKGSLQKNL 492 N+++L GY H+ + Y++ D Y P G L + L Sbjct: 198 PNILRLYGYFHDASRV-------YLILD---------YAPGGELFREL 229
>INSR_HUMAN (P06213) Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220| antigen) [Contains: Insulin receptor alpha subunit; Insulin receptor beta subunit] Length = 1382 Score = 36.6 bits (83), Expect = 0.045 Identities = 24/75 (32%), Positives = 39/75 (52%), Gaps = 6/75 (8%) Frame = +1 Query: 196 RILGTGAFGIVYKGIMPD---GQI---ITVKKLAENSPIAREKAFANEVQNIMALHHENV 357 R LG G+FG+VY+G D G+ + VK + E++ + F NE + +V Sbjct: 1027 RELGQGSFGMVYEGNARDIIKGEAETRVAVKTVNESASLRERIEFLNEASVMKGFTCHHV 1086 Query: 358 VKLVGYCHEGQKKVV 402 V+L+G +GQ +V Sbjct: 1087 VRLLGVVSKGQPTLV 1101
>BMX_MOUSE (P97504) Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2)| (Bone marrow tyrosine kinase gene in chromosome X protein homolog) Length = 651 Score = 36.6 bits (83), Expect = 0.045 Identities = 21/59 (35%), Positives = 27/59 (45%) Frame = +1 Query: 202 LGTGAFGIVYKGIMPDGQIITVKKLAENSPIAREKAFANEVQNIMALHHENVVKLVGYC 378 LG G FG+V G + VK + E + E F E Q +M L H +VK G C Sbjct: 399 LGNGQFGVVQLGQWKGQYDVAVKMIKEGA--MSEDEFFQEAQTMMKLSHPKLVKFYGVC 455
>TIE1_BOVIN (Q06805) Tyrosine-protein kinase receptor Tie-1 precursor (EC| 2.7.10.1) Length = 1136 Score = 36.2 bits (82), Expect = 0.059 Identities = 32/118 (27%), Positives = 54/118 (45%), Gaps = 4/118 (3%) Frame = +1 Query: 139 PKNLPLDFVKTITDQFSEQRILGTGAFGIVYKG-IMPDGQIIT--VKKLAENSPIAREKA 309 P+ PL++ + + + ++G G FG V + I DG + +K L E + + Sbjct: 822 PQPEPLNYPVLEWEDITFEDLIGEGNFGQVIRAMIKKDGLKMNAAIKMLKEYASENDHRD 881 Query: 310 FANEVQNIMAL-HHENVVKLVGYCHEGQKKVVQNNGRYIVADIVESLLCHEYVPKGSL 480 FA E++ + L HH N++ L+G C +N G +A EY P G+L Sbjct: 882 FAGELEVLCKLGHHPNIINLLGAC--------ENRGYLYIA--------IEYAPYGNL 923
>MOS_CHICK (P10741) Serine/threonine-protein kinase mos (EC 2.7.11.1) (Oocyte| maturation factor mos) Length = 349 Score = 36.2 bits (82), Expect = 0.059 Identities = 35/108 (32%), Positives = 56/108 (51%), Gaps = 4/108 (3%) Frame = +1 Query: 58 SSPQXLVQPSAMSTSAGGGQPSVLSTLPKNLP--LDFVKTITDQFSEQRILGTGAFGIVY 231 SSP +V P + GG PS + + LP L + D+ + LG+G FG VY Sbjct: 25 SSP--VVIPGKDGKAFLGGTPSPRT---RRLPPRLAWCSIDWDRLCLLQPLGSGGFGAVY 79 Query: 232 KGIMPDGQIITVKKLAENSP--IAREKAFANEVQNIMALHHENVVKLV 369 K G + VK++ ++S +A ++F E+ N+ L H+NVV++V Sbjct: 80 KATY-HGVTVAVKQVKKSSKNRLASRQSFWAEL-NVARLQHDNVVRVV 125
>KPCD2_HUMAN (Q9BZL6) Serine/threonine-protein kinase D2 (EC 2.7.11.13)| (nPKC-D2) Length = 878 Score = 36.2 bits (82), Expect = 0.059 Identities = 31/106 (29%), Positives = 48/106 (45%), Gaps = 2/106 (1%) Frame = +1 Query: 181 QFSEQRILGTGAFGIVYKG-IMPDGQIITVKKLAE-NSPIAREKAFANEVQNIMALHHEN 354 Q +LG+G FG+VY G G+ + VK + + P +E NEV + +L H Sbjct: 550 QIFPDEVLGSGQFGVVYGGKHRKTGRDVAVKVIDKLRFPTKQESQLRNEVAILQSLRHPG 609 Query: 355 VVKLVGYCHEGQKKVVQNNGRYIVADIVESLLCHEYVPKGSLQKNL 492 +V L +K V + D++E +L E KG L + L Sbjct: 610 IVNLECMFETPEKVFVVMEKLH--GDMLEMILSSE---KGRLPERL 650
>FUS3_YEAST (P16892) Mitogen-activated protein kinase FUS3 (EC 2.7.11.24) (MAP| kinase FUS3) Length = 353 Score = 36.2 bits (82), Expect = 0.059 Identities = 19/74 (25%), Positives = 35/74 (47%), Gaps = 1/74 (1%) Frame = +1 Query: 148 LPLDFVKTITDQFSEQRILGTGAFGIVYKGI-MPDGQIITVKKLAENSPIAREKAFANEV 324 +P V I+ F + +LG GA+G+V P G+I+ +KK+ E+ Sbjct: 1 MPKRIVYNISSDFQLKSLLGEGAYGVVCSATHKPTGEIVAIKKIEPFDKPLFALRTLREI 60 Query: 325 QNIMALHHENVVKL 366 + + HEN++ + Sbjct: 61 KILKHFKHENIITI 74
>INSRR_CAVPO (P14617) Insulin receptor-related protein precursor (EC 2.7.10.1)| (IRR) (IR-related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain] Length = 1300 Score = 36.2 bits (82), Expect = 0.059 Identities = 28/101 (27%), Positives = 46/101 (45%), Gaps = 6/101 (5%) Frame = +1 Query: 118 PSVLSTLPKNLPLDFVKTITDQFSEQRILGTGAFGIVYKGIM------PDGQIITVKKLA 279 P LS +P D + +Q S R LG G+FG+VY+G+ + + +K + Sbjct: 958 PEYLSASDMYIP-DEWEVPREQISIIRELGQGSFGMVYEGVAKGLEAGEESTPVALKTVN 1016 Query: 280 ENSPIAREKAFANEVQNIMALHHENVVKLVGYCHEGQKKVV 402 E + F E + A +VV+L+G +GQ +V Sbjct: 1017 ELASPRERIEFLKEASVMKAFQCHHVVRLLGVVSQGQPTLV 1057
>TEC_MOUSE (P24604) Tyrosine-protein kinase Tec (EC 2.7.10.2)| Length = 630 Score = 36.2 bits (82), Expect = 0.059 Identities = 32/111 (28%), Positives = 51/111 (45%), Gaps = 6/111 (5%) Frame = +1 Query: 127 LSTLPKNLPL------DFVKTITDQFSEQRILGTGAFGIVYKGIMPDGQIITVKKLAENS 288 +ST KN P D + + + R LG+G FG+V G + +K + E + Sbjct: 344 VSTKGKNAPTTAGFSYDKWEINPSELTFMRELGSGLFGVVRLGKWRAQYKVAIKAIREGA 403 Query: 289 PIAREKAFANEVQNIMALHHENVVKLVGYCHEGQKKVVQNNGRYIVADIVE 441 E+ F E + +M L H +V+L G C + QK + YIV + +E Sbjct: 404 MC--EEDFIEEAKVMMKLTHPKLVQLYGVCTQ-QKPI------YIVTEFME 445
>CDC2_PONPY (Q5RCH1) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 36.2 bits (82), Expect = 0.059 Identities = 22/89 (24%), Positives = 45/89 (50%), Gaps = 2/89 (2%) Frame = +1 Query: 178 DQFSEQRILGTGAFGIVYKG-IMPDGQIITVKKL-AENSPIAREKAFANEVQNIMALHHE 351 + +++ +G G +G+VYKG GQ++T+KK+ E+ E+ + L H Sbjct: 2 EDYTKIEKIGEGTYGVVYKGRHKTTGQVVTMKKIRLESEEEGVPSTAIREISLLKELRHP 61 Query: 352 NVVKLVGYCHEGQKKVVQNNGRYIVADIV 438 N+V L Q ++Q++ Y++ + + Sbjct: 62 NIVSL-------QDVLMQDSRLYLIFEFL 83
>M3KL4_HUMAN (Q5TCX8) Mitogen-activated protein kinase kinase kinase (EC| 2.7.11.25) (Mixed lineage kinase 4) Length = 1036 Score = 36.2 bits (82), Expect = 0.059 Identities = 23/91 (25%), Positives = 39/91 (42%), Gaps = 3/91 (3%) Frame = +1 Query: 115 QPSVLSTLPKNLPLDFVKTITDQFSEQRILGTGAFGIVYKGIMPDGQIITVKKL---AEN 285 +P+ P + P V ++ + ++G G FG VY+ GQ + VK E Sbjct: 101 RPAASPAPPPSRPSSPVHVAFERLELKELIGAGGFGQVYRATW-QGQEVAVKAARQDPEQ 159 Query: 286 SPIAREKAFANEVQNIMALHHENVVKLVGYC 378 A ++ E + L H N+++L G C Sbjct: 160 DAAAAAESVRREARLFAMLRHPNIIELRGVC 190
>KIN16_CAEEL (P34892) Receptor-like tyrosine-protein kinase kin-16 precursor (EC| 2.7.10.1) Length = 495 Score = 36.2 bits (82), Expect = 0.059 Identities = 37/149 (24%), Positives = 63/149 (42%), Gaps = 18/149 (12%) Frame = +1 Query: 106 GGGQPSVLSTLPKNLPLDFV------KTITDQFSEQRILGTGAFGIVYKGIM----PDGQ 255 G P L P N LD++ + ++ + ILG+G FG+V KGI+ P + Sbjct: 108 GDAMPEELKNRPLNDKLDYLPYKKQYEIASENLENKSILGSGNFGVVRKGILKMASPKNE 167 Query: 256 -------IITVKKLAENSPIAREKAFANEVQNIMAL-HHENVVKLVGYCHEGQKKVVQNN 411 + VK A I++ A E++ + ++ NV+ LVG +K Sbjct: 168 EEKKMRLTVAVKSAANCYDISQTSMLAAELRLMCSIGRFPNVLALVGAVTSELRK----- 222 Query: 412 GRYIVADIVESLLCHEYVPKGSLQKNLFE 498 GR ++ EY+ G ++K L + Sbjct: 223 GRLLIVT--------EYIDCGDIRKYLID 243
>M3K6_HUMAN (O95382) Mitogen-activated protein kinase kinase kinase 6 (EC| 2.7.11.25) Length = 1011 Score = 36.2 bits (82), Expect = 0.059 Identities = 25/85 (29%), Positives = 44/85 (51%), Gaps = 5/85 (5%) Frame = +1 Query: 148 LPLDFVKTITDQFSEQRILGTGAFGIVYKGIMPDGQI-ITVKKLAENSPIAREKAFANEV 324 L D+ T T E+ +LG G +G+VY G ++ I +K++ E R+ F+ + Sbjct: 362 LEFDYEYTET---GERLVLGKGTYGVVYAGRDRHTRVRIAIKEIPE-----RDSRFSQPL 413 Query: 325 QNIMALH----HENVVKLVGYCHEG 387 +ALH H+N+V+ +G +G Sbjct: 414 HEEIALHRRLRHKNIVRYLGSASQG 438
>CDC2H_PLAYO (Q7RM49) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 289 Score = 36.2 bits (82), Expect = 0.059 Identities = 19/69 (27%), Positives = 32/69 (46%), Gaps = 2/69 (2%) Frame = +1 Query: 202 LGTGAFGIVYKGIMPDGQIITVKK--LAENSPIAREKAFANEVQNIMALHHENVVKLVGY 375 +G G +G+VYK DG+ +KK L + E+ + L H N+VKL Sbjct: 10 IGEGTYGVVYKAQNSDGESFALKKIRLEKEDEGIPSTVSIREISILKELRHSNIVKLYDV 69 Query: 376 CHEGQKKVV 402 H ++ ++ Sbjct: 70 IHAKKRLIL 78
>TESK2_HUMAN (Q96S53) Dual specificity testis-specific protein kinase 2 (EC| 2.7.12.1) (Testicular protein kinase 2) Length = 571 Score = 36.2 bits (82), Expect = 0.059 Identities = 32/124 (25%), Positives = 57/124 (45%), Gaps = 2/124 (1%) Frame = +1 Query: 169 TITDQFSEQRILGTGAFGIVYK-GIMPDGQIITVKKLAENSPIAREKAFANEVQNIMALH 345 T D F+ ++I G+G F V+K GQ++ +K N+ + EVQ + L Sbjct: 54 TRLDDFTCEKI-GSGFFSEVFKVRHRASGQVMALKM---NTLSSNRANMLKEVQLMNRLS 109 Query: 346 HENVVKLVGYC-HEGQKKVVQNNGRYIVADIVESLLCHEYVPKGSLQKNLFEVDTKMDWS 522 H N+++ +G C H+GQ + EY+ G+L++ L + + + W+ Sbjct: 110 HPNILRFMGVCVHQGQLHALT-----------------EYINSGNLEQ-LLDSNLHLPWT 151 Query: 523 TRFK 534 R K Sbjct: 152 VRVK 155
>SRMS_HUMAN (Q9H3Y6) Tyrosine-protein kinase Srms (EC 2.7.10.2)| Length = 488 Score = 36.2 bits (82), Expect = 0.059 Identities = 24/92 (26%), Positives = 43/92 (46%), Gaps = 1/92 (1%) Frame = +1 Query: 118 PSVLSTLPKNLPL-DFVKTITDQFSEQRILGTGAFGIVYKGIMPDGQIITVKKLAENSPI 294 P + +P+ P D + +F+ R LG G FG V++G+ + +K + S Sbjct: 207 PLLQPCMPQKAPRQDVWERPHSEFALGRKLGEGYFGEVWEGLWLGSLPVAIKVI--KSAN 264 Query: 295 AREKAFANEVQNIMALHHENVVKLVGYCHEGQ 390 + A E+Q + L HE +++L C G+ Sbjct: 265 MKLTDLAKEIQTLKGLRHERLIRLHAVCSGGE 296
>KSG7_ARATH (Q39011) Shaggy-related protein kinase eta (EC 2.7.11.1) (ASK-eta)| (BRASSINOSTEROID-INSENSITIVE 2) (ULTRACURVATA1) Length = 380 Score = 36.2 bits (82), Expect = 0.059 Identities = 20/66 (30%), Positives = 39/66 (59%), Gaps = 2/66 (3%) Frame = +1 Query: 175 TDQFSEQRILGTGAFGIVYKG-IMPDGQIITVKKLAENSPIAREKAFAN-EVQNIMALHH 348 T + +R++GTG+FGIV++ + G+ + +KK + +++ + N E+Q + + H Sbjct: 37 TISYMAERVVGTGSFGIVFQAKCLETGETVAIKK------VLQDRRYKNRELQLMRVMDH 90 Query: 349 ENVVKL 366 NVV L Sbjct: 91 PNVVCL 96 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 74,215,453 Number of Sequences: 219361 Number of extensions: 1517878 Number of successful extensions: 5678 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 5381 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5521 length of database: 80,573,946 effective HSP length: 105 effective length of database: 57,541,041 effective search space used: 4200495993 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
