ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | basd14a11 |
|---|---|
| Clone Library Name | barley_pub |
>COPB2_DROME (O62621) Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP)| Length = 914 Score = 121 bits (303), Expect = 2e-27 Identities = 65/201 (32%), Positives = 114/201 (56%) Frame = +2 Query: 41 LEEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEA 220 LE+V F+AH+ +++ +AVHP+ PL+L+ + LIKLW+WEK W C R F H V Sbjct: 89 LEKVHSFEAHSDYLRCIAVHPTQPLVLTSSDDM-LIKLWNWEKMWACQRVFEGHTHYVMQ 147 Query: 221 LQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYI 400 + FNP++++ TFASA+LD K+W + TL+ G+ +DY+ GG++ Y+ Sbjct: 148 IVFNPKDNN----TFASASLDRTVKVWQLGSNFANFTLEGHEKGVNCVDYY-HGGDKPYL 202 Query: 401 ITGSLSGNARIWNLRTHKCIRVIKGTSITSGAGCSVRVVYCSPDPPLLIRTFEDDSLGLC 580 I+G+ +IW+ + C++ ++G + A C P+ P+++ ED ++ + Sbjct: 203 ISGADDRLVKIWDYQNKTCVQTLEGHAQNISAVC------FHPELPIVLTGSEDGTVRIW 256 Query: 581 NSTTFRYTNTIDFGLLRARNI 643 +S T+R +++G R I Sbjct: 257 HSGTYRLETCLNYGFERVWTI 277
>COPB2_MOUSE (O55029) Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP)| (p102) Length = 905 Score = 121 bits (303), Expect = 2e-27 Identities = 63/197 (31%), Positives = 115/197 (58%) Frame = +2 Query: 41 LEEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEA 220 LE V F+AH+ +I+ +AVHP+ P +L+ + LIKLWDW+K W+C + F H V Sbjct: 89 LERVHMFEAHSDYIRCIAVHPTQPFILTSSDDM-LIKLWDWDKKWSCSQVFEGHTHYVMQ 147 Query: 221 LQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYI 400 + NP++++ FASA+LD K+W + P TL+ G+ +DY+ GG++ Y+ Sbjct: 148 IVINPKDNN----QFASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYY-SGGDKPYL 202 Query: 401 ITGSLSGNARIWNLRTHKCIRVIKGTSITSGAGCSVRVVYCSPDPPLLIRTFEDDSLGLC 580 I+G+ +IW+ + C++ ++G + +V P+ P++I ED ++ + Sbjct: 203 ISGADDRLVKIWDYQNKTCVQTLEGHA------QNVSCASFHPELPIIITGSEDGTVRIW 256 Query: 581 NSTTFRYTNTIDFGLLR 631 +S+T+R +T+++G+ R Sbjct: 257 HSSTYRLESTLNYGMER 273
>COPB2_HUMAN (P35606) Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP)| (p102) Length = 905 Score = 121 bits (303), Expect = 2e-27 Identities = 63/197 (31%), Positives = 115/197 (58%) Frame = +2 Query: 41 LEEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEA 220 LE V F+AH+ +I+ +AVHP+ P +L+ + LIKLWDW+K W+C + F H V Sbjct: 88 LERVHMFEAHSDYIRCIAVHPTQPFILTSSDDM-LIKLWDWDKKWSCSQVFEGHTHYVMQ 146 Query: 221 LQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYI 400 + NP++++ FASA+LD K+W + P TL+ G+ +DY+ GG++ Y+ Sbjct: 147 IVINPKDNN----QFASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYY-SGGDKPYL 201 Query: 401 ITGSLSGNARIWNLRTHKCIRVIKGTSITSGAGCSVRVVYCSPDPPLLIRTFEDDSLGLC 580 I+G+ +IW+ + C++ ++G + +V P+ P++I ED ++ + Sbjct: 202 ISGADDRLVKIWDYQNKTCVQTLEGHA------QNVSCASFHPELPIIITGSEDGTVRIW 255 Query: 581 NSTTFRYTNTIDFGLLR 631 +S+T+R +T+++G+ R Sbjct: 256 HSSTYRLESTLNYGMER 272
>COPB2_BOVIN (P35605) Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP)| (p102) Length = 905 Score = 121 bits (303), Expect = 2e-27 Identities = 63/197 (31%), Positives = 115/197 (58%) Frame = +2 Query: 41 LEEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEA 220 LE V F+AH+ +I+ +AVHP+ P +L+ + LIKLWDW+K W+C + F H V Sbjct: 88 LERVHMFEAHSDYIRCIAVHPTQPFILTSSDDM-LIKLWDWDKKWSCSQVFEGHTHYVMQ 146 Query: 221 LQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYI 400 + NP++++ FASA+LD K+W + P TL+ G+ +DY+ GG++ Y+ Sbjct: 147 IVINPKDNN----QFASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYY-SGGDKPYL 201 Query: 401 ITGSLSGNARIWNLRTHKCIRVIKGTSITSGAGCSVRVVYCSPDPPLLIRTFEDDSLGLC 580 I+G+ +IW+ + C++ ++G + +V P+ P++I ED ++ + Sbjct: 202 ISGADDRLVKIWDYQNKTCVQTLEGHA------QNVSCASFHPELPIIITGSEDGTVRIW 255 Query: 581 NSTTFRYTNTIDFGLLR 631 +S+T+R +T+++G+ R Sbjct: 256 HSSTYRLESTLNYGMER 272
>COPB2_RAT (O35142) Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP)| (p102) Length = 904 Score = 119 bits (299), Expect = 6e-27 Identities = 63/197 (31%), Positives = 114/197 (57%) Frame = +2 Query: 41 LEEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEA 220 LE V F+AH+ +I+ +AVHP+ P +L+ + LIKLWDW+K W+C + F H V Sbjct: 88 LERVHMFEAHSDYIRCIAVHPTQPFILTSSDDM-LIKLWDWDKKWSCSQVFEGHTHYVMQ 146 Query: 221 LQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYI 400 + NP++++ FASA+LD K+W + P TL+ G+ +DY+ GG++ Y+ Sbjct: 147 IVINPKDNN----QFASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYY-SGGDKPYL 201 Query: 401 ITGSLSGNARIWNLRTHKCIRVIKGTSITSGAGCSVRVVYCSPDPPLLIRTFEDDSLGLC 580 I+G+ +IW+ + C++ +G + C+ P+ P++I ED ++ + Sbjct: 202 ISGADDRLVKIWDYQNKTCVQTPEGHA--QNVSCAT----FHPELPIIITGSEDGTVRIW 255 Query: 581 NSTTFRYTNTIDFGLLR 631 +S+T+R +T+++G+ R Sbjct: 256 HSSTYRLESTLNYGMER 272
>COPB2_CAEEL (Q20168) Probable coatomer subunit beta' (Beta'-coat protein)| (Beta'-COP) Length = 1000 Score = 119 bits (298), Expect = 8e-27 Identities = 62/197 (31%), Positives = 113/197 (57%) Frame = +2 Query: 41 LEEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEA 220 LE V +F+AH+ ++++L VHP+LP ++S + L+K+WDW+ W ++F H V Sbjct: 89 LERVHQFEAHSDYLRSLVVHPTLPYVISSSDDM-LVKMWDWDNKWAMKQSFEGHTHYVMQ 147 Query: 221 LQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYI 400 + NP++++ TFA+A+LD K+W +P TL+ G+ +DY+ GG + YI Sbjct: 148 IAINPKDNN----TFATASLDKTVKVWQFGSNVPNFTLEGHEKGVNCVDYY-HGGEKPYI 202 Query: 401 ITGSLSGNARIWNLRTHKCIRVIKGTSITSGAGCSVRVVYCSPDPPLLIRTFEDDSLGLC 580 I+G+ +IW+ + C++ + G + + C P+ PL+I ED ++ L Sbjct: 203 ISGADDHLVKIWDYQNKTCVQTLDGHAQNVSSVC------FHPELPLIITGSEDSTVRLW 256 Query: 581 NSTTFRYTNTIDFGLLR 631 ++ T+R +T+++GL R Sbjct: 257 HANTYRQEHTLNYGLER 273
>COPB2_YEAST (P41811) Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP)| Length = 889 Score = 113 bits (283), Expect = 4e-25 Identities = 67/198 (33%), Positives = 108/198 (54%), Gaps = 1/198 (0%) Frame = +2 Query: 44 EEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEAL 223 E+V F+AH +I+++AVHP+ P +LSG + +KLW+WE W +TF H+ V + Sbjct: 88 EKVVDFEAHPDYIRSIAVHPTKPYVLSGS-DDLTVKLWNWENNWALEQTFEGHEHFVMCV 146 Query: 224 QFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDC-QSNGLIDLDYFLPGGNEQYI 400 FNP++ S TFAS LD K+W + P TL Q G+ +DY+ P ++ Y+ Sbjct: 147 AFNPKDPS----TFASGCLDRTVKVWSLGQSTPNFTLTTGQERGVNYVDYY-PLPDKPYM 201 Query: 401 ITGSLSGNARIWNLRTHKCIRVIKGTSITSGAGCSVRVVYCSPDPPLLIRTFEDDSLGLC 580 IT S +IW+ +T C+ ++G +V P P++I ED +L + Sbjct: 202 ITASDDLTIKIWDYQTKSCVATLEGHM------SNVSFAVFHPTLPIIISGSEDGTLKIW 255 Query: 581 NSTTFRYTNTIDFGLLRA 634 NS+T++ T++ GL R+ Sbjct: 256 NSSTYKVEKTLNVGLERS 273
>COPB2_SCHPO (O42937) Probable coatomer subunit beta' (Beta'-coat protein)| (Beta'-COP) Length = 796 Score = 107 bits (267), Expect = 3e-23 Identities = 58/197 (29%), Positives = 107/197 (54%) Frame = +2 Query: 44 EEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEAL 223 E+V +F+AH +I+AL VHP+ P LL+ + IK ++W+ W C++TF H V +L Sbjct: 89 EKVTQFEAHPDYIRALVVHPTQPFLLTSSDDM-TIKCFNWDMSWKCVQTFEGHSRYVMSL 147 Query: 224 QFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYII 403 NP++ + TFAS+ LDG K+W + TL G+ ++Y+ P G++ Y+I Sbjct: 148 AINPKDTN----TFASSCLDGTVKVWSFGSSVANFTLQAHDRGVNYVNYY-PAGDKPYLI 202 Query: 404 TGSLSGNARIWNLRTHKCIRVIKGTSITSGAGCSVRVVYCSPDPPLLIRTFEDDSLGLCN 583 T ++W+ +T C+R+++G + +V + P++I ED ++ + + Sbjct: 203 TAGDDNLIKVWDYQTKACVRILEGHT------NNVSFAFFHSKFPIIISGSEDGTVKIWH 256 Query: 584 STTFRYTNTIDFGLLRA 634 + ++ + +F L RA Sbjct: 257 TLSYSLIKSYNFSLDRA 273
>HETE1_PODAN (Q00808) Vegetatible incompatibility protein HET-E-1| Length = 1356 Score = 69.7 bits (169), Expect = 7e-12 Identities = 52/185 (28%), Positives = 84/185 (45%) Frame = +2 Query: 62 KAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQN 241 + H GW+Q++ P + SG + IK+WD G TC +T H V ++ F+P Sbjct: 1048 EGHGGWVQSVVFSPDGQRVASGS-DDHTIKIWDAVSG-TCTQTLEGHGDSVWSVAFSPDG 1105 Query: 242 DSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSG 421 V AS ++DG KIWD + TL+ G + F P G Q + +GS+ G Sbjct: 1106 QRV-----ASGSIDGTIKIWDAASGTCTQTLEGHG-GWVHSVAFSPDG--QRVASGSIDG 1157 Query: 422 NARIWNLRTHKCIRVIKGTSITSGAGCSVRVVYCSPDPPLLIRTFEDDSLGLCNSTTFRY 601 +IW+ + C T G G V+ V SPD + D ++ + ++ + Sbjct: 1158 TIKIWDAASGTC------TQTLEGHGGWVQSVAFSPDGQRVASGSSDKTIKIWDTASGTC 1211 Query: 602 TNTID 616 T T++ Sbjct: 1212 TQTLE 1216 Score = 60.5 bits (145), Expect = 4e-09 Identities = 49/185 (26%), Positives = 85/185 (45%) Frame = +2 Query: 62 KAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQN 241 + H G + ++A P + SG ++ IK+WD G TC +T H +V+++ F+P Sbjct: 880 EGHGGSVWSVAFSPDRERVASGSDDK-TIKIWDAASG-TCTQTLEGHGGRVQSVAFSPDG 937 Query: 242 DSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSG 421 V AS + D KIWD + TL+ + ++ + F P G Q + +GS Sbjct: 938 QRV-----ASGSDDHTIKIWDAASGTCTQTLEGHGSSVLSV-AFSPDG--QRVASGSGDK 989 Query: 422 NARIWNLRTHKCIRVIKGTSITSGAGCSVRVVYCSPDPPLLIRTFEDDSLGLCNSTTFRY 601 +IW+ + C T G G SV V SPD + +D ++ + ++ + Sbjct: 990 TIKIWDTASGTC------TQTLEGHGGSVWSVAFSPDGQRVASGSDDKTIKIWDTASGTC 1043 Query: 602 TNTID 616 T T++ Sbjct: 1044 TQTLE 1048 Score = 56.6 bits (135), Expect = 6e-08 Identities = 49/185 (26%), Positives = 82/185 (44%) Frame = +2 Query: 62 KAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQN 241 + H G + ++A P + SG ++ IK+WD G TC +T H V+++ F+P Sbjct: 1006 EGHGGSVWSVAFSPDGQRVASGSDDK-TIKIWDTASG-TCTQTLEGHGGWVQSVVFSPDG 1063 Query: 242 DSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSG 421 V AS + D KIWD TL+ + + + F P G Q + +GS+ G Sbjct: 1064 QRV-----ASGSDDHTIKIWDAVSGTCTQTLEGHGDSVWSV-AFSPDG--QRVASGSIDG 1115 Query: 422 NARIWNLRTHKCIRVIKGTSITSGAGCSVRVVYCSPDPPLLIRTFEDDSLGLCNSTTFRY 601 +IW+ + C T G G V V SPD + D ++ + ++ + Sbjct: 1116 TIKIWDAASGTC------TQTLEGHGGWVHSVAFSPDGQRVASGSIDGTIKIWDAASGTC 1169 Query: 602 TNTID 616 T T++ Sbjct: 1170 TQTLE 1174 Score = 52.0 bits (123), Expect = 2e-06 Identities = 33/104 (31%), Positives = 50/104 (48%), Gaps = 1/104 (0%) Frame = +2 Query: 62 KAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQN 241 + H GW+Q++A P + SG ++ IK+WD G TC +T H V+++ F+P Sbjct: 1174 EGHGGWVQSVAFSPDGQRVASGSSDK-TIKIWDTASG-TCTQTLEGHGGWVQSVAFSPDG 1231 Query: 242 DSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNG-LIDLDY 370 V AS + D KIWD + TL+ S + DY Sbjct: 1232 QRV-----ASGSSDNTIKIWDTASGTCTQTLNVGSTATCLSFDY 1270 Score = 38.5 bits (88), Expect = 0.018 Identities = 24/78 (30%), Positives = 39/78 (50%), Gaps = 4/78 (5%) Frame = +2 Query: 62 KAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQ- 238 + H GW+Q++A P + SG + IK+WD G TC +T N + L F+ Sbjct: 1216 EGHGGWVQSVAFSPDGQRVASGS-SDNTIKIWDTASG-TCTQTLNV-GSTATCLSFDYTN 1272 Query: 239 ---NDSVGRTTFASAALD 283 N ++GR A+A ++ Sbjct: 1273 AYINTNIGRIQIATATME 1290
>Y2800_ANASP (Q8YTC2) Hypothetical WD-repeat protein alr2800| Length = 1258 Score = 67.0 bits (162), Expect = 5e-11 Identities = 55/195 (28%), Positives = 88/195 (45%), Gaps = 7/195 (3%) Frame = +2 Query: 50 VKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQF 229 +K H + ++A HP L S ++ IKLWD + G TCL+T H V + F Sbjct: 719 IKTLTGHEHEVFSVAFHPDGETLASASGDK-TIKLWDIQDG-TCLQTLTGHTDWVRCVAF 776 Query: 230 NPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITG 409 +P + T AS+A D K+WD+S + TL + + + + G Q + +G Sbjct: 777 SPDGN-----TLASSAADHTIKLWDVSQGKCLRTLKSHTGWVRSVAFSADG---QTLASG 828 Query: 410 SLSGNARIWNLRTHKCIRVIKGTSITSGAGCSVRVVYCSPDPPLLI-----RTFE--DDS 568 S +IWN T +C++ G + SV + SPD +L+ RT + D Sbjct: 829 SGDRTIKIWNYHTGECLKTYIGHT------NSVYSIAYSPDSKILVSGSGDRTIKLWDCQ 882 Query: 569 LGLCNSTTFRYTNTI 613 +C T +TN + Sbjct: 883 THICIKTLHGHTNEV 897 Score = 66.6 bits (161), Expect = 6e-11 Identities = 49/189 (25%), Positives = 94/189 (49%) Frame = +2 Query: 50 VKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQF 229 ++ K+H GW++++A L SG ++ IK+W++ G CL+T+ H V ++ + Sbjct: 803 LRTLKSHTGWVRSVAFSADGQTLASGSGDR-TIKIWNYHTG-ECLKTYIGHTNSVYSIAY 860 Query: 230 NPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITG 409 +P + + S + D K+WD + I TL +N + + F P G Q + Sbjct: 861 SPDSKIL-----VSGSGDRTIKLWDCQTHICIKTLHGHTNEVCSVA-FSPDG--QTLACV 912 Query: 410 SLSGNARIWNLRTHKCIRVIKGTSITSGAGCSVRVVYCSPDPPLLIRTFEDDSLGLCNST 589 SL + R+WN RT +C++ G + ++ V + SPD +L D ++ L + Sbjct: 913 SLDQSVRLWNCRTGQCLKAWYGNT-----DWALPVAF-SPDRQILASGSNDKTVKLWDWQ 966 Query: 590 TFRYTNTID 616 T +Y ++++ Sbjct: 967 TGKYISSLE 975 Score = 62.0 bits (149), Expect = 2e-09 Identities = 49/175 (28%), Positives = 77/175 (44%) Frame = +2 Query: 68 HNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDS 247 H W++ +A P L S + IKLWD +G CLRT +H V ++ F+ Sbjct: 767 HTDWVRCVAFSPDGNTLASSAADH-TIKLWDVSQG-KCLRTLKSHTGWVRSVAFSADGQ- 823 Query: 248 VGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNA 427 T AS + D KIW+ + T +N + + Y + + +++GS Sbjct: 824 ----TLASGSGDRTIKIWNYHTGECLKTYIGHTNSVYSIAY---SPDSKILVSGSGDRTI 876 Query: 428 RIWNLRTHKCIRVIKGTSITSGAGCSVRVVYCSPDPPLLIRTFEDDSLGLCNSTT 592 ++W+ +TH CI+ + G + CSV SPD L D S+ L N T Sbjct: 877 KLWDCQTHICIKTLHG---HTNEVCSVAF---SPDGQTLACVSLDQSVRLWNCRT 925 Score = 61.6 bits (148), Expect = 2e-09 Identities = 57/206 (27%), Positives = 88/206 (42%), Gaps = 6/206 (2%) Frame = +2 Query: 50 VKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQF 229 +K + + W +A P +L SG N +KLWDW+ G + + H + + F Sbjct: 929 LKAWYGNTDWALPVAFSPDRQILASGS-NDKTVKLWDWQTG-KYISSLEGHTDFIYGIAF 986 Query: 230 NPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDY-----FLPGGNEQ 394 +P + T ASA+ D ++W+IS T C L D+ F P G + Sbjct: 987 SPDSQ-----TLASASTDSSVRLWNIS------TGQCFQILLEHTDWVYAVVFHPQG--K 1033 Query: 395 YIITGSLSGNARIWNLRTHKCIRVIKGTSITSGAGCSVRVVYCSPDPPLLIRTFEDDSLG 574 I TGS ++WN+ T +C++ + S + + SPD LL D S+ Sbjct: 1034 IIATGSADCTVKLWNISTGQCLKTL------SEHSDKILGMAWSPDGQLLASASADQSVR 1087 Query: 575 LCNSTTFRYTNTIDFGLLRAR-NIVY 649 L + T R G+LR N VY Sbjct: 1088 LWDCCTGRCV-----GILRGHSNRVY 1108 Score = 58.5 bits (140), Expect = 2e-08 Identities = 50/191 (26%), Positives = 87/191 (45%), Gaps = 7/191 (3%) Frame = +2 Query: 62 KAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQN 241 + H+ W++ + P +L S G ++ +KLW G C++T H+ +V ++ F+P Sbjct: 681 RGHSNWVRFVVFSPDGEILASCGADEN-VKLWSVRDG-VCIKTLTGHEHEVFSVAFHPDG 738 Query: 242 DSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSG 421 + T ASA+ D K+WDI + TL ++ + F P GN + + + Sbjct: 739 E-----TLASASGDKTIKLWDIQDGTCLQTLTGHTD-WVRCVAFSPDGNT--LASSAADH 790 Query: 422 NARIWNLRTHKCIRVIKGTSITSGAGCSVRVVYCSPDPPLLIRTFEDDSL-------GLC 580 ++W++ KC+R +K S G VR V S D L D ++ G C Sbjct: 791 TIKLWDVSQGKCLRTLK-----SHTGW-VRSVAFSADGQTLASGSGDRTIKIWNYHTGEC 844 Query: 581 NSTTFRYTNTI 613 T +TN++ Sbjct: 845 LKTYIGHTNSV 855 Score = 57.4 bits (137), Expect = 4e-08 Identities = 37/149 (24%), Positives = 71/149 (47%), Gaps = 5/149 (3%) Frame = +2 Query: 62 KAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQN 241 + H+ + + P+ ++ + +Q +K+WDW++G CL+T H V + F+P Sbjct: 1101 RGHSNRVYSAIFSPNGEIIATCSTDQ-TVKIWDWQQG-KCLKTLTGHTNWVFDIAFSPDG 1158 Query: 242 DSVGRTTFASAALDGKAKIWDISLILPIATLDCQS-----NGLIDLDYFLPGGNEQYIIT 406 + ASA+ D +IWD++ T C L+ F P G + + + Sbjct: 1159 KIL-----ASASHDQTVRIWDVN------TGKCHHICIGHTHLVSSVAFSPDG--EVVAS 1205 Query: 407 GSLSGNARIWNLRTHKCIRVIKGTSITSG 493 GS RIWN++T +C+++++ + G Sbjct: 1206 GSQDQTVRIWNVKTGECLQILRAKRLYEG 1234
>YY46_ANASP (Q8YRI1) Hypothetical WD-repeat protein alr3466| Length = 1526 Score = 65.9 bits (159), Expect = 1e-10 Identities = 48/202 (23%), Positives = 92/202 (45%) Frame = +2 Query: 44 EEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEAL 223 +E+ K HN W+ ++ +L SG +Q ++LWD G CL+TF H ++V ++ Sbjct: 897 KELLTCKGHNSWVNSVGFSQDGKMLASGSDDQ-TVRLWDISSG-QCLKTFKGHTSRVRSV 954 Query: 224 QFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYII 403 F+P + AS + D ++WDIS + + + + + L G + Sbjct: 955 VFSPNS-----LMLASGSSDQTVRLWDISSGECLYIFQGHTGWVYSVAFNLDG---SMLA 1006 Query: 404 TGSLSGNARIWNLRTHKCIRVIKGTSITSGAGCSVRVVYCSPDPPLLIRTFEDDSLGLCN 583 TGS R+W++ + +C + +G + VR V S D +L +D ++ L + Sbjct: 1007 TGSGDQTVRLWDISSSQCFYIFQGHT------SCVRSVVFSSDGAMLASGSDDQTVRLWD 1060 Query: 584 STTFRYTNTIDFGLLRARNIVY 649 ++ T+ R++V+ Sbjct: 1061 ISSGNCLYTLQGHTSCVRSVVF 1082 Score = 58.2 bits (139), Expect = 2e-08 Identities = 43/173 (24%), Positives = 78/173 (45%) Frame = +2 Query: 59 FKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQ 238 F+ H W+ ++ +P +L SG ++ ++LWD CL TF H V ++ FNP Sbjct: 1238 FQGHTSWVNSVVFNPDGSMLASGSSDK-TVRLWDISSS-KCLHTFQGHTNWVNSVAFNPD 1295 Query: 239 NDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLS 418 + AS + D ++W+IS + T ++ + + F P G + +GS Sbjct: 1296 G-----SMLASGSGDQTVRLWEISSSKCLHTFQGHTSWVSSVT-FSPDGT--MLASGSDD 1347 Query: 419 GNARIWNLRTHKCIRVIKGTSITSGAGCSVRVVYCSPDPPLLIRTFEDDSLGL 577 R+W++ + +C+ G + G+ V SPD +L D ++ L Sbjct: 1348 QTVRLWSISSGECLYTFLGHTNWVGS------VIFSPDGAILASGSGDQTVRL 1394 Score = 58.2 bits (139), Expect = 2e-08 Identities = 38/138 (27%), Positives = 69/138 (50%) Frame = +2 Query: 62 KAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQN 241 + H ++++ P +L SGG +Q +++LWD G CL T + + V L F+P Sbjct: 1071 QGHTSCVRSVVFSPDGAMLASGGDDQ-IVRLWDISSG-NCLYTLQGYTSWVRFLVFSPNG 1128 Query: 242 DSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSG 421 T A+ + D ++WDIS + TL +N ++ F P G + +GS Sbjct: 1129 -----VTLANGSSDQIVRLWDISSKKCLYTLQGHTNW-VNAVAFSPDGAT--LASGSGDQ 1180 Query: 422 NARIWNLRTHKCIRVIKG 475 R+W++ + KC+ +++G Sbjct: 1181 TVRLWDISSSKCLYILQG 1198 Score = 57.8 bits (138), Expect = 3e-08 Identities = 36/138 (26%), Positives = 65/138 (47%) Frame = +2 Query: 62 KAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQN 241 + H W+ A+A P L SG +Q ++LWD CL H + V ++ FNP Sbjct: 1155 QGHTNWVNAVAFSPDGATLASGSGDQ-TVRLWDISSS-KCLYILQGHTSWVNSVVFNPDG 1212 Query: 242 DSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSG 421 +T AS + D ++W+I+ + T ++ + + F P G+ + +GS Sbjct: 1213 -----STLASGSSDQTVRLWEINSSKCLCTFQGHTSWVNSV-VFNPDGS--MLASGSSDK 1264 Query: 422 NARIWNLRTHKCIRVIKG 475 R+W++ + KC+ +G Sbjct: 1265 TVRLWDISSSKCLHTFQG 1282 Score = 56.2 bits (134), Expect = 8e-08 Identities = 38/145 (26%), Positives = 66/145 (45%) Frame = +2 Query: 59 FKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQ 238 F H W+ ++ P +L SG +Q ++LW G CL T H V ++ F+P Sbjct: 1364 FLGHTNWVGSVIFSPDGAILASGSGDQ-TVRLWSISSG-KCLYTLQGHNNWVGSIVFSPD 1421 Query: 239 NDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLS 418 T AS + D ++W+IS + TL N + + + G + +GS Sbjct: 1422 G-----TLLASGSDDQTVRLWNISSGECLYTLHGHINSVRSVAFSSDG---LILASGSDD 1473 Query: 419 GNARIWNLRTHKCIRVIKGTSITSG 493 ++W+++T +CI+ +K I G Sbjct: 1474 ETIKLWDVKTGECIKTLKSEKIYEG 1498
>WDS_DROME (Q9V3J8) Protein will die slowly| Length = 361 Score = 65.1 bits (157), Expect = 2e-10 Identities = 38/144 (26%), Positives = 68/144 (47%) Frame = +2 Query: 44 EEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEAL 223 + +K K H+ ++ +P L++SG ++ +++WD G CL+T AH V A+ Sbjct: 147 KSLKTLKGHSNYVFCCNFNPQSNLIVSGSFDES-VRIWDVRTG-KCLKTLPAHSDPVSAV 204 Query: 224 QFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYII 403 FN + S++ DG +IWD + + TL N + F P G +YI+ Sbjct: 205 HFNRDGSLI-----VSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNG--KYIL 257 Query: 404 TGSLSGNARIWNLRTHKCIRVIKG 475 +L ++W+ KC++ G Sbjct: 258 AATLDNTLKLWDYSKGKCLKTYTG 281 Score = 46.6 bits (109), Expect = 7e-05 Identities = 44/171 (25%), Positives = 77/171 (45%) Frame = +2 Query: 68 HNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDS 247 H + A+ P+ L S ++ LIK+W G +T + HK + + ++ + Sbjct: 71 HTKAVSAVKFSPNGEWLASSSADK-LIKIWGAYDG-KFEKTISGHKLGISDVAWSSDS-- 126 Query: 248 VGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNA 427 S + D K+W++S + TL SN + + F P N I++GS + Sbjct: 127 ---RLLVSGSDDKTLKVWELSTGKSLKTLKGHSNYVFCCN-FNPQSN--LIVSGSFDESV 180 Query: 428 RIWNLRTHKCIRVIKGTSITSGAGCSVRVVYCSPDPPLLIRTFEDDSLGLC 580 RIW++RT KC++ + S V V+ + D L++ + D GLC Sbjct: 181 RIWDVRTGKCLKTLPAHS------DPVSAVHFNRDGSLIVSSSYD---GLC 222
>WDR5_MOUSE (P61965) WD-repeat protein 5 (BMP2-induced 3-kb gene protein)| (WD-repeat protein BIG-3) Length = 334 Score = 65.1 bits (157), Expect = 2e-10 Identities = 38/142 (26%), Positives = 68/142 (47%) Frame = +2 Query: 50 VKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQF 229 +K K H+ ++ +P L++SG ++ +++WD + G CL+T AH V A+ F Sbjct: 122 LKTLKGHSNYVFCCNFNPQSNLIVSGSFDES-VRIWDVKTG-KCLKTLPAHSDPVSAVHF 179 Query: 230 NPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITG 409 N + S++ DG +IWD + + TL N + F P G +YI+ Sbjct: 180 NRDGSLI-----VSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNG--KYILAA 232 Query: 410 SLSGNARIWNLRTHKCIRVIKG 475 +L ++W+ KC++ G Sbjct: 233 TLDNTLKLWDYSKGKCLKTYTG 254 Score = 47.8 bits (112), Expect = 3e-05 Identities = 45/171 (26%), Positives = 80/171 (46%) Frame = +2 Query: 68 HNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDS 247 H + ++ P+ L S ++ LIK+W G +T + HK + + ++ ++ Sbjct: 44 HTKAVSSVKFSPNGEWLASSSADK-LIKIWGAYDG-KFEKTISGHKLGISDVAWSSDSNL 101 Query: 248 VGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNA 427 + SA+ D KIWD+S + TL SN + + F P N I++GS + Sbjct: 102 L-----VSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCN-FNPQSN--LIVSGSFDESV 153 Query: 428 RIWNLRTHKCIRVIKGTSITSGAGCSVRVVYCSPDPPLLIRTFEDDSLGLC 580 RIW+++T KC++ + S V V+ + D L++ + D GLC Sbjct: 154 RIWDVKTGKCLKTLPAHS------DPVSAVHFNRDGSLIVSSSYD---GLC 195
>WDR5_HUMAN (P61964) WD-repeat protein 5 (BMP2-induced 3-kb gene protein)| Length = 334 Score = 65.1 bits (157), Expect = 2e-10 Identities = 38/142 (26%), Positives = 68/142 (47%) Frame = +2 Query: 50 VKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQF 229 +K K H+ ++ +P L++SG ++ +++WD + G CL+T AH V A+ F Sbjct: 122 LKTLKGHSNYVFCCNFNPQSNLIVSGSFDES-VRIWDVKTG-KCLKTLPAHSDPVSAVHF 179 Query: 230 NPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITG 409 N + S++ DG +IWD + + TL N + F P G +YI+ Sbjct: 180 NRDGSLI-----VSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNG--KYILAA 232 Query: 410 SLSGNARIWNLRTHKCIRVIKG 475 +L ++W+ KC++ G Sbjct: 233 TLDNTLKLWDYSKGKCLKTYTG 254 Score = 47.8 bits (112), Expect = 3e-05 Identities = 45/171 (26%), Positives = 80/171 (46%) Frame = +2 Query: 68 HNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDS 247 H + ++ P+ L S ++ LIK+W G +T + HK + + ++ ++ Sbjct: 44 HTKAVSSVKFSPNGEWLASSSADK-LIKIWGAYDG-KFEKTISGHKLGISDVAWSSDSNL 101 Query: 248 VGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNA 427 + SA+ D KIWD+S + TL SN + + F P N I++GS + Sbjct: 102 L-----VSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCN-FNPQSN--LIVSGSFDESV 153 Query: 428 RIWNLRTHKCIRVIKGTSITSGAGCSVRVVYCSPDPPLLIRTFEDDSLGLC 580 RIW+++T KC++ + S V V+ + D L++ + D GLC Sbjct: 154 RIWDVKTGKCLKTLPAHS------DPVSAVHFNRDGSLIVSSSYD---GLC 195
>NUDF_EMENI (Q00664) Nuclear migration protein nudF| Length = 444 Score = 64.3 bits (155), Expect = 3e-10 Identities = 44/140 (31%), Positives = 64/140 (45%), Gaps = 1/140 (0%) Frame = +2 Query: 65 AHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQND 244 +H + +A HP L SG IK+WDWE G RT H V L + Q Sbjct: 112 SHRDAVTCVAFHPVFTSLASGS-EDCTIKIWDWELG-EIERTLKGHIRGVSGLDYGGQK- 168 Query: 245 SVGRTTFASAALDGKAKIWDISL-ILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSG 421 G T AS + D K+WD S I TL + + + + N+ ++I+ S G Sbjct: 169 --GNTLLASCSSDLTIKLWDPSKDYANIRTLSGHDHSVSSVRFLT--SNDNHLISASRDG 224 Query: 422 NARIWNLRTHKCIRVIKGTS 481 RIW++ T C++VIK + Sbjct: 225 TLRIWDVSTGFCVKVIKSAT 244 Score = 45.1 bits (105), Expect = 2e-04 Identities = 31/108 (28%), Positives = 49/108 (45%), Gaps = 8/108 (7%) Frame = +2 Query: 119 LSGGCNQGL-IKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAK 295 L C+ L IKLWD K + +RT + H V +++F ND+ SA+ DG + Sbjct: 172 LLASCSSDLTIKLWDPSKDYANIRTLSGHDHSVSSVRFLTSNDN----HLISASRDGTLR 227 Query: 296 IWDISLILPIATLDCQSNGLI-------DLDYFLPGGNEQYIITGSLS 418 IWD+S + + + I D + + GG +Q I +S Sbjct: 228 IWDVSTGFCVKVIKSATESWIRDVSPSFDGKWLVSGGRDQAITVWEVS 275 Score = 30.0 bits (66), Expect = 6.3 Identities = 16/63 (25%), Positives = 30/63 (47%), Gaps = 1/63 (1%) Frame = +2 Query: 50 VKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFN-AHKAKVEALQ 226 +K H+ W++ L HP L S + I+ WD + ++T + AH+ V ++ Sbjct: 342 IKTLHGHDNWVRGLVFHPGGKYLFSVS-DDKTIRCWDLSQEGRLVKTISGAHEHFVSCIR 400 Query: 227 FNP 235 + P Sbjct: 401 WAP 403
>YKY4_CAEEL (Q17963) Hypothetical WD-repeat protein C14B1.4| Length = 376 Score = 63.2 bits (152), Expect = 7e-10 Identities = 43/155 (27%), Positives = 72/155 (46%), Gaps = 6/155 (3%) Frame = +2 Query: 29 KTLGLEEV------KKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRT 190 KTL + E+ K K HN ++ +P L++SG ++ +++WD + G C++T Sbjct: 151 KTLKIFEIVTSRMTKTLKGHNNYVFCCNFNPQSSLVVSGSFDES-VRIWDVKTGM-CIKT 208 Query: 191 FNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDY 370 AH V A+ FN + AS + DG +IWD + I TL N + Sbjct: 209 LPAHSDPVSAVSFNRDGSLI-----ASGSYDGLVRIWDTANGQCIKTLVDDENPPVAFVK 263 Query: 371 FLPGGNEQYIITGSLSGNARIWNLRTHKCIRVIKG 475 F P G +YI+ +L ++W+ K ++ G Sbjct: 264 FSPNG--KYILASNLDSTLKLWDFSKGKTLKQYTG 296 Score = 49.7 bits (117), Expect = 8e-06 Identities = 42/145 (28%), Positives = 73/145 (50%), Gaps = 3/145 (2%) Frame = +2 Query: 50 VKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTF-NAHKAKVEALQ 226 +K AH+ + A++ + L+ SG + GL+++WD G C++T + V ++ Sbjct: 206 IKTLPAHSDPVSAVSFNRDGSLIASGSYD-GLVRIWDTANG-QCIKTLVDDENPPVAFVK 263 Query: 227 FNPQNDSVGRTTFASAALDGKAKIWDIS--LILPIATLDCQSNGLIDLDYFLPGGNEQYI 400 F+P G+ AS LD K+WD S L T S I ++ + GG ++I Sbjct: 264 FSPN----GKYILAS-NLDSTLKLWDFSKGKTLKQYTGHENSKYCIFANFSVTGG--KWI 316 Query: 401 ITGSLSGNARIWNLRTHKCIRVIKG 475 I+GS IWNL+T + ++ ++G Sbjct: 317 ISGSEDCKIYIWNLQTREIVQCLEG 341 Score = 38.9 bits (89), Expect = 0.014 Identities = 27/112 (24%), Positives = 51/112 (45%) Frame = +2 Query: 146 IKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPI 325 +K+W+ + C RT HK V + ++ + V SA+ D KI++I Sbjct: 111 VKIWNMDH-MICERTLTGHKLGVNDIAWSSDSRCV-----VSASDDKTLKIFEIVTSRMT 164 Query: 326 ATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNARIWNLRTHKCIRVIKGTS 481 TL +N + ++ +++GS + RIW+++T CI+ + S Sbjct: 165 KTLKGHNNYVFCCNF---NPQSSLVVSGSFDESVRIWDVKTGMCIKTLPAHS 213
>KTNB1_BRARE (Q7ZUV2) Katanin p80 WD40-containing subunit B1 homolog| Length = 694 Score = 61.2 bits (147), Expect = 3e-09 Identities = 42/177 (23%), Positives = 81/177 (45%) Frame = +2 Query: 47 EVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQ 226 ++++ AH+ + +L + S LL+ G + +W K C+ + H + V +Q Sbjct: 12 KLQEIVAHSSNVSSLVLGKSSGRLLATGGEDCRVNIWAVSKP-NCIMSLTGHTSAVGCIQ 70 Query: 227 FNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIIT 406 FN + V + +L G ++WD+ + TL + LD+ G +Y+ + Sbjct: 71 FNSSEERV-----VAGSLSGSLRLWDLEAAKILRTLMGHKASISSLDFHPMG---EYLAS 122 Query: 407 GSLSGNARIWNLRTHKCIRVIKGTSITSGAGCSVRVVYCSPDPPLLIRTFEDDSLGL 577 GS+ N ++W++R C+ KG + +VR + SPD L +D ++ L Sbjct: 123 GSVDSNIKLWDVRRKGCVFRYKGHT------QAVRCLAFSPDGKWLASASDDSTVKL 173 Score = 44.3 bits (103), Expect = 3e-04 Identities = 43/156 (27%), Positives = 70/156 (44%) Frame = +2 Query: 128 GCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDI 307 G G ++LWD E LRT HKA + +L F+P + + AS ++D K+WD+ Sbjct: 81 GSLSGSLRLWDLEAA-KILRTLMGHKASISSLDFHPMGEYL-----ASGSVDSNIKLWDV 134 Query: 308 SLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNARIWNLRTHKCIRVIKGTSIT 487 + + + L F P G +++ + S ++W+L K I + TS T Sbjct: 135 RRKGCVFRYKGHTQAVRCL-AFSPDG--KWLASASDDSTVKLWDLIAGKMI--TEFTSHT 189 Query: 488 SGAGCSVRVVYCSPDPPLLIRTFEDDSLGLCNSTTF 595 S +V VV P+ LL D ++ L + F Sbjct: 190 S----AVNVVQFHPNEYLLASGSADRTVKLWDLEKF 221 Score = 33.9 bits (76), Expect = 0.44 Identities = 18/62 (29%), Positives = 32/62 (51%) Frame = +2 Query: 50 VKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQF 229 + +F +H + + HP+ LL SG ++ +KLWD EK + + + V ++ F Sbjct: 182 ITEFTSHTSAVNVVQFHPNEYLLASGSADR-TVKLWDLEK-FNMIGSSEGETGVVRSVLF 239 Query: 230 NP 235 NP Sbjct: 240 NP 241
>UTP13_SCHPO (Q9USN3) Probable U3 small nucleolar RNA-associated protein 13 (U3| snoRNA-associated protein 13) Length = 777 Score = 60.8 bits (146), Expect = 3e-09 Identities = 38/140 (27%), Positives = 70/140 (50%) Frame = +2 Query: 50 VKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQF 229 +K KAH + + + P+ LL +GG +GL+K+WD G +F H + AL F Sbjct: 96 IKSMKAHETPVITMTIDPTNTLLATGGA-EGLVKVWD-IAGAYVTHSFRGHGGVISALCF 153 Query: 230 NPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITG 409 ++ AS A D + ++WD++ +A + S+ + L F P G+ ++++G Sbjct: 154 GKHQNT---WVLASGADDSRVRLWDLNSSRSMAVFEGHSSVIRGLT-FEPTGS--FLLSG 207 Query: 410 SLSGNARIWNLRTHKCIRVI 469 S ++WN++ +R I Sbjct: 208 SRDKTVQVWNIKKRSAVRTI 227 Score = 46.2 bits (108), Expect = 9e-05 Identities = 32/136 (23%), Positives = 63/136 (46%) Frame = +2 Query: 62 KAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQN 241 KAH+ + A+ V ++ S ++ IKLWD G + H+ V A FNP + Sbjct: 462 KAHDRDVNAIQVSKDGRIIASASQDK-TIKLWDSSTG-EVVGVLRGHRRGVWACSFNPFS 519 Query: 242 DSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSG 421 + AS + D +IW++ + TL+ + ++ L Y G +++ + G Sbjct: 520 RQL-----ASGSGDRTIRIWNVDTQQCVQTLEGHTGAILKLIYISQGTQ---VVSAAADG 571 Query: 422 NARIWNLRTHKCIRVI 469 ++W+L + +C+ + Sbjct: 572 LVKVWSLSSGECVATL 587 Score = 38.5 bits (88), Expect = 0.018 Identities = 28/113 (24%), Positives = 50/113 (44%) Frame = +2 Query: 188 TFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLD 367 T AH V A+Q + + ASA+ D K+WD S + L G+ Sbjct: 460 TIKAHDRDVNAIQVSKDGRII-----ASASQDKTIKLWDSSTGEVVGVLRGHRRGVWACS 514 Query: 368 YFLPGGNEQYIITGSLSGNARIWNLRTHKCIRVIKGTSITSGAGCSVRVVYCS 526 + + + +GS RIWN+ T +C++ ++G + G ++++Y S Sbjct: 515 F---NPFSRQLASGSGDRTIRIWNVDTQQCVQTLEGHT-----GAILKLIYIS 559 Score = 37.4 bits (85), Expect = 0.040 Identities = 34/139 (24%), Positives = 58/139 (41%) Frame = +2 Query: 44 EEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEAL 223 E V + H + A + +P L SG ++ I++W+ + C++T H + L Sbjct: 498 EVVGVLRGHRRGVWACSFNPFSRQLASGSGDR-TIRIWNVDTQ-QCVQTLEGHTGAILKL 555 Query: 224 QFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYII 403 + Q V SAA DG K+W +S +ATLD + + L G ++ Sbjct: 556 IYISQGTQV-----VSAAADGLVKVWSLSSGECVATLDNHEDRVWALASRFDG---SLLV 607 Query: 404 TGSLSGNARIWNLRTHKCI 460 +G +W T + I Sbjct: 608 SGGADAVVSVWKDVTEEYI 626
>SPG16_MOUSE (Q8K450) Sperm-associated antigen 16 protein (PF20 protein homolog)| Length = 639 Score = 56.2 bits (134), Expect = 8e-08 Identities = 41/136 (30%), Positives = 62/136 (45%) Frame = +2 Query: 68 HNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDS 247 H W+ HPS L + IKLWD KG C T H V + ++ D Sbjct: 401 HTDWLSGCCFHPSGSKLATSS-GDSTIKLWDLNKG-ECTLTLEGHNHAVWSCTWHSCGDF 458 Query: 248 VGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNA 427 V ASA+LD +KIWD++ TL ++ + +++F P N ++T S Sbjct: 459 V-----ASASLDMTSKIWDVNSERCRYTLYGHTDSVNSIEFF-PFSN--ILLTASADKTL 510 Query: 428 RIWNLRTHKCIRVIKG 475 +W+ RT KC + + G Sbjct: 511 SVWDARTGKCEQSLYG 526 Score = 35.0 bits (79), Expect = 0.20 Identities = 22/90 (24%), Positives = 39/90 (43%) Frame = +2 Query: 68 HNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDS 247 H + ++ P +LL+ ++ L +WD G C ++ H V F P+ Sbjct: 485 HTDSVNSIEFFPFSNILLTASADKTL-SVWDARTG-KCEQSLYGHMHSVNDATFTPRGHI 542 Query: 248 VGRTTFASAALDGKAKIWDISLILPIATLD 337 + AS G K+WD ++PI ++D Sbjct: 543 I-----ASCDARGVTKLWDFRKLIPIVSID 567
>TB1RB_XENLA (Q6GPC6) F-box-like/WD-repeat-containing protein TBL1XR1-B| (Transducin beta-like 1X-related homolog 1-B) (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1-B) (TBL1-related protein 1-B) Length = 522 Score = 56.2 bits (134), Expect = 8e-08 Identities = 40/156 (25%), Positives = 71/156 (45%), Gaps = 5/156 (3%) Frame = +2 Query: 26 CKTLGLEEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGL-IKLWDWEKGWTCLRTFNAH 202 CK +K F+ H + A+ P+ LL S C+ + +K+W + TC+ AH Sbjct: 342 CKLGQDRPIKTFQGHTNEVNAIKWDPTGNLLAS--CSDDMTLKIWSMKHD-TCVHDLQAH 398 Query: 203 KAKVEALQFNPQ----NDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDY 370 ++ ++++P N+ ASA+ D ++WD+ + I TL + + Sbjct: 399 NKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVA- 457 Query: 371 FLPGGNEQYIITGSLSGNARIWNLRTHKCIRVIKGT 478 F P G +Y+ +GS IWN +T + +GT Sbjct: 458 FSPDG--RYLASGSFDKCVHIWNTQTGALVHSYRGT 491
>TB1RA_XENLA (Q7SZM9) F-box-like/WD-repeat-containing protein TBL1XR1-A| (Transducin beta-like 1X-related protein 1-A) (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1-A) (TBL1-related protein 1-A) (xTBLR1) Length = 519 Score = 56.2 bits (134), Expect = 8e-08 Identities = 40/156 (25%), Positives = 71/156 (45%), Gaps = 5/156 (3%) Frame = +2 Query: 26 CKTLGLEEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGL-IKLWDWEKGWTCLRTFNAH 202 CK +K F+ H + A+ P+ LL S C+ + +K+W + TC+ AH Sbjct: 339 CKLGQDRPIKTFQGHTNEVNAIKWDPTGNLLAS--CSDDMTLKIWSMKHD-TCVHDLQAH 395 Query: 203 KAKVEALQFNPQ----NDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDY 370 ++ ++++P N+ ASA+ D ++WD+ + I TL + + Sbjct: 396 NKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVA- 454 Query: 371 FLPGGNEQYIITGSLSGNARIWNLRTHKCIRVIKGT 478 F P G +Y+ +GS IWN +T + +GT Sbjct: 455 FSPDG--RYLASGSFDKCVHIWNTQTGALVHSYRGT 488
>PRP46_YARLI (Q6C709) Pre-mRNA-splicing factor PRP46 (Pre-mRNA-processing| protein 46) Length = 472 Score = 55.5 bits (132), Expect = 1e-07 Identities = 36/130 (27%), Positives = 62/130 (47%) Frame = +2 Query: 80 IQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRT 259 ++AL V P P + SGG ++ ++K WD E +R ++ H + V +L +P D Sbjct: 208 VRALGVSPRHPYMFSGGEDK-MVKCWDLETN-KVVRHYHGHLSAVYSLDIHPTLD----- 260 Query: 260 TFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNARIWN 439 SA D A++WDI P+ L + + + + +E +IT S R+WN Sbjct: 261 VLVSAGRDAVARVWDIRTRDPVVVLSGHKSTINRVKF---QASEPQVITASADETVRLWN 317 Query: 440 LRTHKCIRVI 469 L+ K + + Sbjct: 318 LQAGKTMTTL 327 Score = 43.9 bits (102), Expect = 4e-04 Identities = 39/172 (22%), Positives = 68/172 (39%) Frame = +2 Query: 68 HNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDS 247 H GW++++ V P +G ++ IK+WD G L T H V AL +P++ Sbjct: 162 HQGWVRSVCVEPENQWFATGSADK-TIKIWDLATGKLRL-TLTGHIMGVRALGVSPRHPY 219 Query: 248 VGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNA 427 + S D K WD+ + + + LD +++ A Sbjct: 220 M-----FSGGEDKMVKCWDLETNKVVRHYHGHLSAVYSLDIH---PTLDVLVSAGRDAVA 271 Query: 428 RIWNLRTHKCIRVIKGTSITSGAGCSVRVVYCSPDPPLLIRTFEDDSLGLCN 583 R+W++RT + V+ G T + V P +I D+++ L N Sbjct: 272 RVWDIRTRDPVVVLSGHKST------INRVKFQASEPQVITASADETVRLWN 317
>WDR57_PONPY (Q5RF51) WD-repeat protein 57| Length = 357 Score = 55.1 bits (131), Expect = 2e-07 Identities = 35/148 (23%), Positives = 69/148 (46%), Gaps = 4/148 (2%) Frame = +2 Query: 44 EEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEAL 223 E VK+ K H ++ + P L+ G + G +KLWD K ++TF + +V A+ Sbjct: 142 ERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRKK-AAIQTFQ-NTYQVLAV 199 Query: 224 QFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYII 403 FN +D + S +D K+WD+ T+ ++ + L G Y++ Sbjct: 200 TFNDTSDQI-----ISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLSLSSEG---SYLL 251 Query: 404 TGSLSGNARIWNLR----THKCIRVIKG 475 + ++ R+W++R +C+++ +G Sbjct: 252 SNAMDNTVRVWDVRPFAPKERCVKIFQG 279 Score = 36.6 bits (83), Expect = 0.068 Identities = 35/154 (22%), Positives = 59/154 (38%) Frame = +2 Query: 17 PAXCKTLGLEEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFN 196 P C +L + H G + HP+ L S G ++ LI LW+ T Sbjct: 49 PPRCSSLQAP-IMLLSGHEGEVYCCKFHPNGSTLASAGFDR-LILLWNVYGDCGNYATLK 106 Query: 197 AHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFL 376 + V L +N + SA+ D +WD + L ++ ++ Y Sbjct: 107 GYSGAVMELHYNTDGSML-----FSASTDKTVAVWDSETGERVKRLKGHTS-FVNSCYPA 160 Query: 377 PGGNEQYIITGSLSGNARIWNLRTHKCIRVIKGT 478 G Q + TGS G ++W++R I+ + T Sbjct: 161 RRG-PQLVCTGSDDGTVKLWDIRKKAAIQTFQNT 193
>WDR57_HUMAN (Q96DI7) WD-repeat protein 57 (Prp8-binding protein) (hPRP8BP) (U5| snRNP-specific 40 kDa protein) (38 kDa splicing factor) Length = 357 Score = 55.1 bits (131), Expect = 2e-07 Identities = 35/148 (23%), Positives = 69/148 (46%), Gaps = 4/148 (2%) Frame = +2 Query: 44 EEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEAL 223 E VK+ K H ++ + P L+ G + G +KLWD K ++TF + +V A+ Sbjct: 142 ERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRKK-AAIQTFQ-NTYQVLAV 199 Query: 224 QFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYII 403 FN +D + S +D K+WD+ T+ ++ + L G Y++ Sbjct: 200 TFNDTSDQI-----ISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLSLSSEG---SYLL 251 Query: 404 TGSLSGNARIWNLR----THKCIRVIKG 475 + ++ R+W++R +C+++ +G Sbjct: 252 SNAMDNTVRVWDVRPFAPKERCVKIFQG 279 Score = 39.3 bits (90), Expect = 0.010 Identities = 36/154 (23%), Positives = 59/154 (38%) Frame = +2 Query: 17 PAXCKTLGLEEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFN 196 P C +L + H G + HP+ L S G ++ LI LW+ T Sbjct: 49 PPRCSSLQAP-IMLLSGHEGEVYCCKFHPNGSTLASAGFDR-LILLWNVYGDCDNYATLK 106 Query: 197 AHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFL 376 H V L +N + SA+ D +WD + L ++ ++ Y Sbjct: 107 GHSGAVMELHYNTDGSML-----FSASTDKTVAVWDSETGERVKRLKGHTS-FVNSCYPA 160 Query: 377 PGGNEQYIITGSLSGNARIWNLRTHKCIRVIKGT 478 G Q + TGS G ++W++R I+ + T Sbjct: 161 RRG-PQLVCTGSDDGTVKLWDIRKKAAIQTFQNT 193
>TBL1R_MOUSE (Q8BHJ5) F-box-like/WD-repeat protein TBL1XR1 (Transducin beta-like| 1X-related protein 1) (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1) (TBL1-related protein 1) Length = 514 Score = 55.1 bits (131), Expect = 2e-07 Identities = 39/156 (25%), Positives = 71/156 (45%), Gaps = 5/156 (3%) Frame = +2 Query: 26 CKTLGLEEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGL-IKLWDWEKGWTCLRTFNAH 202 CK +K F+ H + A+ P+ LL S C+ + +K+W ++ C+ AH Sbjct: 334 CKLGQDRPIKTFQGHTNEVNAIKWDPTGNLLAS--CSDDMTLKIWSMKQD-NCVHDLQAH 390 Query: 203 KAKVEALQFNPQ----NDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDY 370 ++ ++++P N+ ASA+ D ++WD+ + I TL + + Sbjct: 391 NKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVA- 449 Query: 371 FLPGGNEQYIITGSLSGNARIWNLRTHKCIRVIKGT 478 F P G +Y+ +GS IWN +T + +GT Sbjct: 450 FSPDG--RYLASGSFDKCVHIWNTQTGALVHSYRGT 483
>TBL1R_HUMAN (Q9BZK7) F-box-like/WD-repeat protein TBL1XR1 (Transducin beta-like| 1X-related protein 1) (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1) (TBL1-related protein 1) Length = 514 Score = 55.1 bits (131), Expect = 2e-07 Identities = 39/156 (25%), Positives = 71/156 (45%), Gaps = 5/156 (3%) Frame = +2 Query: 26 CKTLGLEEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGL-IKLWDWEKGWTCLRTFNAH 202 CK +K F+ H + A+ P+ LL S C+ + +K+W ++ C+ AH Sbjct: 334 CKLGQDRPIKTFQGHTNEVNAIKWDPTGNLLAS--CSDDMTLKIWSMKQD-NCVHDLQAH 390 Query: 203 KAKVEALQFNPQ----NDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDY 370 ++ ++++P N+ ASA+ D ++WD+ + I TL + + Sbjct: 391 NKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVA- 449 Query: 371 FLPGGNEQYIITGSLSGNARIWNLRTHKCIRVIKGT 478 F P G +Y+ +GS IWN +T + +GT Sbjct: 450 FSPDG--RYLASGSFDKCVHIWNTQTGALVHSYRGT 483
>WDR57_MOUSE (Q6PE01) WD-repeat protein 57| Length = 358 Score = 54.7 bits (130), Expect = 2e-07 Identities = 35/148 (23%), Positives = 69/148 (46%), Gaps = 4/148 (2%) Frame = +2 Query: 44 EEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEAL 223 E VK+ K H ++ + P L+ G + G +KLWD K ++TF + +V A+ Sbjct: 143 ERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRKK-AAVQTFQ-NTYQVLAV 200 Query: 224 QFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYII 403 FN +D + S +D K+WD+ T+ ++ + L G Y++ Sbjct: 201 TFNDTSDQI-----ISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLSLSSEG---SYLL 252 Query: 404 TGSLSGNARIWNLR----THKCIRVIKG 475 + ++ R+W++R +C+++ +G Sbjct: 253 SNAMDNTVRVWDVRPFAPKERCVKIFQG 280 Score = 38.9 bits (89), Expect = 0.014 Identities = 35/154 (22%), Positives = 59/154 (38%) Frame = +2 Query: 17 PAXCKTLGLEEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFN 196 P C +L + H G + HP+ L S G ++ LI LW+ T Sbjct: 50 PPRCSSLQAP-IMLLSGHEGEVYCCKFHPNGSTLASAGFDR-LILLWNVYGDCDNYATLK 107 Query: 197 AHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFL 376 H V L +N + SA+ D +WD + L ++ ++ Y Sbjct: 108 GHSGAVMELHYNTDGSML-----FSASTDKTVAVWDSETGERVKRLKGHTS-FVNSCYPA 161 Query: 377 PGGNEQYIITGSLSGNARIWNLRTHKCIRVIKGT 478 G Q + TGS G ++W++R ++ + T Sbjct: 162 RRG-PQLVCTGSDDGTVKLWDIRKKAAVQTFQNT 194
>FBXW7_HUMAN (Q969H0) F-box/WD-repeat protein 7 (F-box and WD-40 domain protein| 7) (F-box protein FBX30) (hCdc4) (Archipelago homolog) (hAgo) (SEL-10) Length = 707 Score = 54.7 bits (130), Expect = 2e-07 Identities = 38/143 (26%), Positives = 65/143 (45%), Gaps = 1/143 (0%) Frame = +2 Query: 68 HNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDS 247 H ++ + +H + G +++WD E G CL H A V +Q++ Sbjct: 460 HTSTVRCMHLHEKRVV---SGSRDATLRVWDIETG-QCLHVLMGHVAAVRCVQYD----- 510 Query: 248 VGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNA 427 GR S A D K+WD + TL +N + L + + ++++GSL + Sbjct: 511 -GRRV-VSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF-----DGIHVVSGSLDTSI 563 Query: 428 RIWNLRTHKCIRVIKG-TSITSG 493 R+W++ T CI + G S+TSG Sbjct: 564 RVWDVETGNCIHTLTGHQSLTSG 586 Score = 42.7 bits (99), Expect = 0.001 Identities = 34/128 (26%), Positives = 60/128 (46%), Gaps = 3/128 (2%) Frame = +2 Query: 146 IKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPI 325 I++WD E G C+ T H++ ++ D++ S D KIWDI + Sbjct: 563 IRVWDVETG-NCIHTLTGHQSLTSGMELK---DNI----LVSGNADSTVKIWDIKTGQCL 614 Query: 326 ATL---DCQSNGLIDLDYFLPGGNEQYIITGSLSGNARIWNLRTHKCIRVIKGTSITSGA 496 TL + + + L + N+ ++IT S G ++W+L+T + IR + +T + Sbjct: 615 QTLQGPNKHQSAVTCLQF-----NKNFVITSSDDGTVKLWDLKTGEFIRNL----VTLES 665 Query: 497 GCSVRVVY 520 G S VV+ Sbjct: 666 GGSGGVVW 673 Score = 37.7 bits (86), Expect = 0.030 Identities = 28/116 (24%), Positives = 52/116 (44%) Frame = +2 Query: 128 GCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDI 307 G + +K+W G CLRT H V + Q D++ S + D K+W+ Sbjct: 397 GSDDNTLKVWSAVTG-KCLRTLVGHTGGVWSSQMR---DNI----IISGSTDRTLKVWNA 448 Query: 308 SLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNARIWNLRTHKCIRVIKG 475 I TL ++ + + +E+ +++GS R+W++ T +C+ V+ G Sbjct: 449 ETGECIHTLYGHTSTVRCMHL-----HEKRVVSGSRDATLRVWDIETGQCLHVLMG 499
>PKWA_THECU (P49695) Probable serine/threonine-protein kinase pkwA (EC| 2.7.11.1) Length = 742 Score = 54.7 bits (130), Expect = 2e-07 Identities = 45/159 (28%), Positives = 72/159 (45%) Frame = +2 Query: 116 LLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAK 295 LL+GG LI +WD G L T H V A+ F+P AS + D + Sbjct: 473 LLAGGSGDKLIHVWDVASGDE-LHTLEGHTDWVRAVAFSPDG-----ALLASGSDDATVR 526 Query: 296 IWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNARIWNLRTHKCIRVIKG 475 +WD++ A + ++ ++D+ F P G+ + +GS G AR+WN+ T V+KG Sbjct: 527 LWDVAAAEERAVFEGHTHYVLDIA-FSPDGS--MVASGSRDGTARLWNVATGTEHAVLKG 583 Query: 476 TSITSGAGCSVRVVYCSPDPPLLIRTFEDDSLGLCNSTT 592 + V V SPD ++ D ++ L + T Sbjct: 584 HT------DYVYAVAFSPDGSMVASGSRDGTIRLWDVAT 616 Score = 47.4 bits (111), Expect = 4e-05 Identities = 31/91 (34%), Positives = 48/91 (52%), Gaps = 2/91 (2%) Frame = +2 Query: 44 EEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDW--EKGWTCLRTFNAHKAKVE 217 E + F+ H W++A+A P LL SG ++ I+LWD ++ T T H V Sbjct: 659 EALHTFEGHTDWVRAVAFSPDGALLASGSDDR-TIRLWDVAAQEEHT---TLEGHTEPVH 714 Query: 218 ALQFNPQNDSVGRTTFASAALDGKAKIWDIS 310 ++ F+P+ TT ASA+ DG +IW I+ Sbjct: 715 SVAFHPEG-----TTLASASEDGTIRIWPIA 740
>FBXW7_MOUSE (Q8VBV4) F-box/WD-repeat protein 7 (F-box and WD-40 domain protein| 7) (F-box protein FBW7) (F-box protein Fbxw6) (F-box-WD40 repeat protein 6) (SEL-10) Length = 629 Score = 54.7 bits (130), Expect = 2e-07 Identities = 38/143 (26%), Positives = 65/143 (45%), Gaps = 1/143 (0%) Frame = +2 Query: 68 HNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDS 247 H ++ + +H + G +++WD E G CL H A V +Q++ Sbjct: 382 HTSTVRCMHLHEKRVV---SGSRDATLRVWDIETG-QCLHVLMGHVAAVRCVQYD----- 432 Query: 248 VGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNA 427 GR S A D K+WD + TL +N + L + + ++++GSL + Sbjct: 433 -GRRV-VSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF-----DGIHVVSGSLDTSI 485 Query: 428 RIWNLRTHKCIRVIKG-TSITSG 493 R+W++ T CI + G S+TSG Sbjct: 486 RVWDVETGNCIHTLTGHQSLTSG 508 Score = 49.7 bits (117), Expect = 8e-06 Identities = 29/118 (24%), Positives = 57/118 (48%) Frame = +2 Query: 128 GCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDI 307 G ++K+WD E TCL T H +V +LQF+ + S +LD ++WD+ Sbjct: 439 GAYDFMVKVWDPETE-TCLHTLQGHTNRVYSLQFDGIH-------VVSGSLDTSIRVWDV 490 Query: 308 SLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNARIWNLRTHKCIRVIKGTS 481 I TL + ++ + +++G+ +IW+++T +C++ ++G S Sbjct: 491 ETGNCIHTLTGHQSLTSGMEL-----KDNILVSGNADSTVKIWDIKTGQCLQTLQGPS 543 Score = 43.5 bits (101), Expect = 6e-04 Identities = 35/128 (27%), Positives = 60/128 (46%), Gaps = 3/128 (2%) Frame = +2 Query: 146 IKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPI 325 I++WD E G C+ T H++ ++ D++ S D KIWDI + Sbjct: 485 IRVWDVETG-NCIHTLTGHQSLTSGMELK---DNI----LVSGNADSTVKIWDIKTGQCL 536 Query: 326 ATLDCQS---NGLIDLDYFLPGGNEQYIITGSLSGNARIWNLRTHKCIRVIKGTSITSGA 496 TL S + + L + N+ ++IT S G ++W+L+T + IR + +T + Sbjct: 537 QTLQGPSKHQSAVTCLQF-----NKNFVITSSDDGTVKLWDLKTGEFIRNL----VTLES 587 Query: 497 GCSVRVVY 520 G S VV+ Sbjct: 588 GGSGGVVW 595 Score = 37.7 bits (86), Expect = 0.030 Identities = 28/116 (24%), Positives = 52/116 (44%) Frame = +2 Query: 128 GCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDI 307 G + +K+W G CLRT H V + Q D++ S + D K+W+ Sbjct: 319 GSDDNTLKVWSAVTG-KCLRTLVGHTGGVWSSQMR---DNI----IISGSTDRTLKVWNA 370 Query: 308 SLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNARIWNLRTHKCIRVIKG 475 I TL ++ + + +E+ +++GS R+W++ T +C+ V+ G Sbjct: 371 ETGECIHTLYGHTSTVRCMHL-----HEKRVVSGSRDATLRVWDIETGQCLHVLMG 421
>DIP2_YEAST (Q12220) DOM34-interacting protein 2 (U3 small nucleolar| RNA-associated protein 12) (U3 snoRNA-associated protein 12) Length = 943 Score = 54.3 bits (129), Expect = 3e-07 Identities = 38/115 (33%), Positives = 58/115 (50%) Frame = +2 Query: 116 LLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAK 295 LL+ G G+IK+WD T L FN HKA + LQF D G T S + D Sbjct: 93 LLAVGYADGVIKVWDLMSK-TVLLNFNGHKAAITLLQF----DGTG-TRLISGSKDSNII 146 Query: 296 IWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNARIWNLRTHKCI 460 +WD L+ + +S+ ++ G E ++I+ S G ++W+L+TH+CI Sbjct: 147 VWD--LVGEVGLYKLRSHKDSITGFWCQG--EDWLISTSKDGMIKLWDLKTHQCI 197 Score = 32.7 bits (73), Expect = 0.98 Identities = 10/29 (34%), Positives = 21/29 (72%) Frame = +2 Query: 386 NEQYIITGSLSGNARIWNLRTHKCIRVIK 472 ++ ++ + +G+ +IWN++THKCIR + Sbjct: 401 DDNKLLATASNGSLKIWNIKTHKCIRTFE 429
>MSI1_ARATH (O22467) WD-40 repeat protein MSI1 (Protein MULTICOPY SUPPRESSOR OF| IRA 1) (Protein medicis) Length = 424 Score = 54.3 bits (129), Expect = 3e-07 Identities = 36/117 (30%), Positives = 61/117 (52%) Frame = +2 Query: 50 VKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQF 229 V+ AH+ + LA +P +++ G +KL+D K T L TF++HK +V + + Sbjct: 266 VQSVVAHSMEVNCLAFNPFNEWVVATGSTDKTVKLFDLRKLSTALHTFDSHKEEVFQVGW 325 Query: 230 NPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYI 400 NP+N+ T AS L + +WD+S I T++ +G +L F+ GG+ I Sbjct: 326 NPKNE----TILASCCLGRRLMVWDLSRIDEEQTVEDAEDGPPEL-LFIHGGHTSKI 377
>TAF5_HUMAN (Q15542) Transcription initiation factor TFIID subunit 5| (Transcription initiation factor TFIID 100 kDa subunit) (TAF(II)100) (TAFII-100) (TAFII100) Length = 800 Score = 54.3 bits (129), Expect = 3e-07 Identities = 34/132 (25%), Positives = 63/132 (47%) Frame = +2 Query: 44 EEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEAL 223 + ++ F H + HP+ + +G ++ ++LWD G C+R F HK + +L Sbjct: 618 QPLRIFAGHLADVNCTRFHPNSNYVATGSADR-TVRLWDVLNG-NCVRIFTGHKGPIHSL 675 Query: 224 QFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYII 403 F+P GR A+ A DG+ +WDI L + L ++ + L + G + + Sbjct: 676 TFSPN----GR-FLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDG---EILA 727 Query: 404 TGSLSGNARIWN 439 +GS+ R+W+ Sbjct: 728 SGSMDNTVRLWD 739 Score = 52.8 bits (125), Expect = 9e-07 Identities = 37/143 (25%), Positives = 59/143 (41%) Frame = +2 Query: 47 EVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQ 226 E+K H+G + + P LLS G ++LW + +TCL + H V Q Sbjct: 535 ELKILYGHSGPVYGASFSPDRNYLLSSS-EDGTVRLWSLQT-FTCLVGYKGHNYPVWDTQ 592 Query: 227 FNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIIT 406 F+P F S D A++W P+ + L D++ N Y+ T Sbjct: 593 FSPYG-----YYFVSGGHDRVARLWATDHYQPLRIF---AGHLADVNCTRFHPNSNYVAT 644 Query: 407 GSLSGNARIWNLRTHKCIRVIKG 475 GS R+W++ C+R+ G Sbjct: 645 GSADRTVRLWDVLNGNCVRIFTG 667 Score = 40.4 bits (93), Expect = 0.005 Identities = 47/188 (25%), Positives = 83/188 (44%), Gaps = 1/188 (0%) Frame = +2 Query: 59 FKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQ 238 +K HN + P +SGG ++ + +LW + + LR F H A V +F+P Sbjct: 581 YKGHNYPVWDTQFSPYGYYFVSGGHDR-VARLWATDH-YQPLRIFAGHLADVNCTRFHPN 638 Query: 239 NDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLS 418 ++ V A+ + D ++WD+ L + G I F P G +++ TG+ Sbjct: 639 SNYV-----ATGSADRTVRLWDV-LNGNCVRIFTGHKGPIHSLTFSPNG--RFLATGATD 690 Query: 419 GNARIWNLRTHKCIRVIKGTSITSGAGCSVRVVYCSPDPPLLIRTFEDDSLGLCNS-TTF 595 G +W++ + +KG + T CS+R S D +L D+++ L ++ F Sbjct: 691 GRVLLWDIGHGLMVGELKGHTDTV---CSLRF---SRDGEILASGSMDNTVRLWDAIKAF 744 Query: 596 RYTNTIDF 619 T DF Sbjct: 745 EDLETDDF 752
>TAF5_MOUSE (Q8C092) Transcription initiation factor TFIID subunit 5| (Transcription initiation factor TFIID 100 kDa subunit) (TAF(II)100) (TAFII-100) (TAFII100) Length = 801 Score = 54.3 bits (129), Expect = 3e-07 Identities = 34/132 (25%), Positives = 63/132 (47%) Frame = +2 Query: 44 EEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEAL 223 + ++ F H + HP+ + +G ++ ++LWD G C+R F HK + +L Sbjct: 619 QPLRIFAGHLADVNCTRYHPNSNYVATGSADR-TVRLWDVLNG-NCVRIFTGHKGPIHSL 676 Query: 224 QFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYII 403 F+P GR A+ A DG+ +WDI L + L ++ + L + G + + Sbjct: 677 TFSPN----GR-FLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDG---EILA 728 Query: 404 TGSLSGNARIWN 439 +GS+ R+W+ Sbjct: 729 SGSMDNTVRLWD 740 Score = 53.1 bits (126), Expect = 7e-07 Identities = 37/143 (25%), Positives = 59/143 (41%) Frame = +2 Query: 47 EVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQ 226 E+K H+G + + P LLS G ++LW + +TCL + H V Q Sbjct: 536 ELKILYGHSGPVYGASFSPDRNYLLSSS-EDGTVRLWSLQT-FTCLVGYKGHNYPVWDTQ 593 Query: 227 FNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIIT 406 F+P F S D A++W P+ + L D++ N Y+ T Sbjct: 594 FSPYG-----YYFVSGGHDRVARLWATDHYQPLRIF---AGHLADVNCTRYHPNSNYVAT 645 Query: 407 GSLSGNARIWNLRTHKCIRVIKG 475 GS R+W++ C+R+ G Sbjct: 646 GSADRTVRLWDVLNGNCVRIFTG 668 Score = 39.7 bits (91), Expect = 0.008 Identities = 46/188 (24%), Positives = 83/188 (44%), Gaps = 1/188 (0%) Frame = +2 Query: 59 FKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQ 238 +K HN + P +SGG ++ + +LW + + LR F H A V +++P Sbjct: 582 YKGHNYPVWDTQFSPYGYYFVSGGHDR-VARLWATDH-YQPLRIFAGHLADVNCTRYHPN 639 Query: 239 NDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLS 418 ++ V A+ + D ++WD+ L + G I F P G +++ TG+ Sbjct: 640 SNYV-----ATGSADRTVRLWDV-LNGNCVRIFTGHKGPIHSLTFSPNG--RFLATGATD 691 Query: 419 GNARIWNLRTHKCIRVIKGTSITSGAGCSVRVVYCSPDPPLLIRTFEDDSLGLCNST-TF 595 G +W++ + +KG + T CS+R S D +L D+++ L ++ F Sbjct: 692 GRVLLWDIGHGLMVGELKGHTDTV---CSLRF---SRDGEILASGSMDNTVRLWDAVKAF 745 Query: 596 RYTNTIDF 619 T DF Sbjct: 746 EDLETDDF 753
>PRP46_CANGA (Q6FJZ9) Pre-mRNA-splicing factor PRP46 (Pre-mRNA-processing| protein 46) Length = 427 Score = 53.9 bits (128), Expect = 4e-07 Identities = 40/136 (29%), Positives = 67/136 (49%) Frame = +2 Query: 62 KAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQN 241 KAH+ ++ LA+ P + S ++ +K WD EK T +R ++ H + V + +P Sbjct: 155 KAHDMTVRDLAISNRHPYMFSVSEDK-TVKCWDLEKN-TAIRNYHGHLSGVHTVDIHPTV 212 Query: 242 DSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSG 421 D V +A D K+WDI LP+ TL G I LP + +I+ S+ Sbjct: 213 DVV-----VTAGRDSVVKVWDIRTRLPVMTLP-GHKGPITKVRCLP--VDPQVISSSVDA 264 Query: 422 NARIWNLRTHKCIRVI 469 + R+W+L K ++V+ Sbjct: 265 SIRLWDLVAGKSMKVL 280
>COPA_HUMAN (P53621) Coatomer subunit alpha (Alpha-coat protein) (Alpha-COP)| (HEPCOP) (HEP-COP) [Contains: Xenin (Xenopsin-related peptide); Proxenin] Length = 1224 Score = 53.5 bits (127), Expect = 5e-07 Identities = 39/143 (27%), Positives = 67/143 (46%), Gaps = 3/143 (2%) Frame = +2 Query: 56 KFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNP 235 KF+ + ++ L+ HP P +L+ + G+I+LWD+ + T + F+ H V + F+ Sbjct: 4 KFETKSARVKGLSFHPKRPWILT-SLHNGVIQLWDY-RMCTLIDKFDEHDGPVRGIDFHK 61 Query: 236 QNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLP---GGNEQYIIT 406 Q + F S D K K+W+ L + TL L LDY +I++ Sbjct: 62 Q-----QPLFVSGGDDYKIKVWNYKLRRCLFTL------LGHLDYIRTTFFHHEYPWILS 110 Query: 407 GSLSGNARIWNLRTHKCIRVIKG 475 S R+WN ++ C+ V+ G Sbjct: 111 ASDDQTIRVWNWQSRTCVCVLTG 133 Score = 42.7 bits (99), Expect = 0.001 Identities = 38/172 (22%), Positives = 62/172 (36%), Gaps = 45/172 (26%) Frame = +2 Query: 50 VKKFKAHNGWIQALAVHPSLPLLLSGG--------------------------------- 130 + KF H+G ++ + H PL +SGG Sbjct: 44 IDKFDEHDGPVRGIDFHKQQPLFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHH 103 Query: 131 --------CNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDG 286 + I++W+W+ TC+ H V QF+P D V SA+LD Sbjct: 104 EYPWILSASDDQTIRVWNWQSR-TCVCVLTGHNHYVMCAQFHPTEDLV-----VSASLDQ 157 Query: 287 KAKIWDISLI----LPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNAR 430 ++WDIS + L ++ G+ +D F G ++ L G+ R Sbjct: 158 TVRVWDISGLRKKNLSPGAVESDVRGITGVDLF---GTTDAVVKHVLEGHDR 206 Score = 36.2 bits (82), Expect = 0.088 Identities = 22/85 (25%), Positives = 42/85 (49%), Gaps = 2/85 (2%) Frame = +2 Query: 62 KAHNGWIQALAVHPSLPLLLSGGCNQGLIKLW--DWEKGWTCLRTFNAHKAKVEALQFNP 235 + H+ + A HP++PL++S G + +K+W + K W + T H V F+P Sbjct: 202 EGHDRGVNWAAFHPTMPLIVS-GADDRQVKIWRMNESKAWE-VDTCRGHYNNVSCAVFHP 259 Query: 236 QNDSVGRTTFASAALDGKAKIWDIS 310 + + + S + D ++WD+S Sbjct: 260 RQELI-----LSNSEDKSIRVWDMS 279
>COPA_BOVIN (Q27954) Coatomer subunit alpha (Alpha-coat protein) (Alpha-COP)| (HEPCOP) (HEP-COP) [Contains: Xenin (Xenopsin-related peptide); Proxenin] Length = 1224 Score = 53.5 bits (127), Expect = 5e-07 Identities = 39/143 (27%), Positives = 67/143 (46%), Gaps = 3/143 (2%) Frame = +2 Query: 56 KFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNP 235 KF+ + ++ L+ HP P +L+ + G+I+LWD+ + T + F+ H V + F+ Sbjct: 4 KFETKSARVKGLSFHPKRPWILT-SLHNGVIQLWDY-RMCTLIDKFDEHDGPVRGIDFHK 61 Query: 236 QNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLP---GGNEQYIIT 406 Q + F S D K K+W+ L + TL L LDY +I++ Sbjct: 62 Q-----QPLFVSGGDDYKIKVWNYKLRRCLFTL------LGHLDYIRTTFFHHEYPWILS 110 Query: 407 GSLSGNARIWNLRTHKCIRVIKG 475 S R+WN ++ C+ V+ G Sbjct: 111 ASDDQTIRVWNWQSRTCVCVLTG 133 Score = 43.1 bits (100), Expect = 7e-04 Identities = 38/172 (22%), Positives = 62/172 (36%), Gaps = 45/172 (26%) Frame = +2 Query: 50 VKKFKAHNGWIQALAVHPSLPLLLSGG--------------------------------- 130 + KF H+G ++ + H PL +SGG Sbjct: 44 IDKFDEHDGPVRGIDFHKQQPLFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHH 103 Query: 131 --------CNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDG 286 + I++W+W+ TC+ H V QF+P D V SA+LD Sbjct: 104 EYPWILSASDDQTIRVWNWQSR-TCVCVLTGHNHYVMCAQFHPSEDLV-----VSASLDQ 157 Query: 287 KAKIWDISLI----LPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNAR 430 ++WDIS + L ++ G+ +D F G ++ L G+ R Sbjct: 158 TVRVWDISGLRKKNLSPGAVESDVRGITGVDLF---GTTDAVVKHVLEGHDR 206 Score = 36.2 bits (82), Expect = 0.088 Identities = 22/85 (25%), Positives = 42/85 (49%), Gaps = 2/85 (2%) Frame = +2 Query: 62 KAHNGWIQALAVHPSLPLLLSGGCNQGLIKLW--DWEKGWTCLRTFNAHKAKVEALQFNP 235 + H+ + A HP++PL++S G + +K+W + K W + T H V F+P Sbjct: 202 EGHDRGVNWAAFHPTMPLIVS-GADDRQVKIWRMNESKAWE-VDTCRGHYNNVSCAVFHP 259 Query: 236 QNDSVGRTTFASAALDGKAKIWDIS 310 + + + S + D ++WD+S Sbjct: 260 RQELI-----LSNSEDKSIRVWDMS 279
>TBLX_MOUSE (Q9QXE7) F-box-like/WD-repeat protein TBL1X (Transducin beta-like| 1X protein) Length = 527 Score = 53.5 bits (127), Expect = 5e-07 Identities = 37/148 (25%), Positives = 68/148 (45%), Gaps = 5/148 (3%) Frame = +2 Query: 50 VKKFKAHNGWIQALAVHPSLPLLLSGGCNQGL-IKLWDWEKGWTCLRTFNAHKAKVEALQ 226 VK F+ H + A+ PS LL S C+ + +K+W ++ C+ AH ++ ++ Sbjct: 355 VKTFQGHTNEVNAIKWDPSGMLLAS--CSDDMTLKIWSMKQD-ACVHDLQAHSKEIYTIK 411 Query: 227 FNPQNDSVGRTT----FASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQ 394 ++P + ASA+ D ++WD+ + I TL + + F P G + Sbjct: 412 WSPTGPATSNPNSNIMLASASFDSTVRLWDVERGVCIHTLTKHQEPVYSVA-FSPDG--K 468 Query: 395 YIITGSLSGNARIWNLRTHKCIRVIKGT 478 Y+ +GS IWN ++ + +GT Sbjct: 469 YLASGSFDKCVHIWNTQSGSLVHSYRGT 496
>PF20_CHLRE (P93107) Flagellar WD-repeat protein PF20| Length = 606 Score = 53.5 bits (127), Expect = 5e-07 Identities = 53/212 (25%), Positives = 86/212 (40%), Gaps = 7/212 (3%) Frame = +2 Query: 14 PPAXCKTLGLEEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTF 193 P A K L L K FK H + LA+HP+ P+L++ ++ K+W G + Sbjct: 309 PAAPVKMLSLN--KTFKGHLLSVANLALHPTKPILVTASDDKTW-KMWHMPGG-DLIMCG 364 Query: 194 NAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYF 373 HK V + F+P T AS D KIWD + T + + + Sbjct: 365 EGHKDWVAGVDFHPAG-----TCLASGGGDSAVKIWDFEKQRCVTTFTDHKQAIWSVRFH 419 Query: 374 LPGGNEQYIITGSLSGNARIWNLRTHKCIRVIKG----TSITSGAGCSVRVVYCSPDPPL 541 G + + +GSL R+W+L KC ++G + + S + S D + Sbjct: 420 HLG---EVVASGSLDHTVRLWDLPAGKCRMALRGHVDSVNDLAWQPFSSSLATASSDKTV 476 Query: 542 LIRTFEDDSLGLCNSTTFRYTNT---IDFGLL 628 + D GLC T + + N+ + F +L Sbjct: 477 SV---WDARAGLCTQTYYGHQNSCNGVSFNIL 505 Score = 35.8 bits (81), Expect = 0.12 Identities = 23/92 (25%), Positives = 40/92 (43%) Frame = +2 Query: 62 KAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQN 241 + H + LA P L + ++ + +WD G C +T+ H+ + FN Sbjct: 449 RGHVDSVNDLAWQPFSSSLATASSDK-TVSVWDARAG-LCTQTYYGHQNSCNGVSFN--- 503 Query: 242 DSVGRTTFASAALDGKAKIWDISLILPIATLD 337 + T AS DG K+WD + +AT++ Sbjct: 504 --ILGTQLASTDADGVVKLWDTRMTAEVATIN 533
>TAF5_DROME (P49846) Transcription initiation factor TFIID subunit 5| (Transcription initiation factor TFIID 85 kDa subunit) (p85) (TAFII-80) Length = 704 Score = 53.1 bits (126), Expect = 7e-07 Identities = 51/197 (25%), Positives = 85/197 (43%), Gaps = 7/197 (3%) Frame = +2 Query: 44 EEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQ-GLIKLWDWEKGWTCLRTFNAHKAKVEA 220 E + H G + A P + LLLS C++ I+LW W+C+ T+ H V Sbjct: 441 EVTRSLMGHTGPVYRCAFAPEMNLLLS--CSEDSTIRLWSLLT-WSCVVTYRGHVYPVWD 497 Query: 221 LQFNPQNDSVGRTTFASAALDGKAKIW--DISLILPIATLDCQSNGLIDLDYFLPGGNEQ 394 ++F P F S + D A++W D + L + L D+D N Sbjct: 498 VRFAPHG-----YYFVSCSYDKTARLWATDSNQALRVFV-----GHLSDVDCVQFHPNSN 547 Query: 395 YIITGSLSGNARIWNLRTHKCIRVIKG----TSITSGAGCSVRVVYCSPDPPLLIRTFED 562 Y+ TGS R+W+ T + +R++ G S + + C + S D ++I + Sbjct: 548 YVATGSSDRTVRLWDNMTGQSVRLMTGHKGSVSSLAFSACGRYLASGSVDHNIIIWDLSN 607 Query: 563 DSLGLCNSTTFRYTNTI 613 SL +T R+T+T+ Sbjct: 608 GSL---VTTLLRHTSTV 621
>KTNB1_ARATH (Q8H0T9) Katanin p80 WD40-containing subunit B1 homolog 1| Length = 837 Score = 52.8 bits (125), Expect = 9e-07 Identities = 45/173 (26%), Positives = 78/173 (45%) Frame = +2 Query: 47 EVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQ 226 ++++F AH+ + L + +L G + LW K L + H + ++++ Sbjct: 8 KLQEFVAHSAAVNCLKIGRKSSRVLVTGGEDHKVNLWAIGKPNAILSLYG-HSSGIDSVT 66 Query: 227 FNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIIT 406 F+ V A+ A G K+WD+ + TL + I +D F P G ++ + Sbjct: 67 FDASEVLV-----AAGAASGTIKLWDLEEAKIVRTLTGHRSNCISVD-FHPFG--EFFAS 118 Query: 407 GSLSGNARIWNLRTHKCIRVIKGTSITSGAGCSVRVVYCSPDPPLLIRTFEDD 565 GSL N +IW++R CI KG T G V V+ +PD ++ ED+ Sbjct: 119 GSLDTNLKIWDIRKKGCIHTYKGH--TRG----VNVLRFTPDGRWVVSGGEDN 165 Score = 47.8 bits (112), Expect = 3e-05 Identities = 43/168 (25%), Positives = 63/168 (37%), Gaps = 3/168 (1%) Frame = +2 Query: 8 GXPPAXCKTLGLEE---VKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWT 178 G K LEE V+ H ++ HP SG + L K+WD K Sbjct: 77 GAASGTIKLWDLEEAKIVRTLTGHRSNCISVDFHPFGEFFASGSLDTNL-KIWDIRKKG- 134 Query: 179 CLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLI 358 C+ T+ H V L+F P V S D K+WD++ + + Sbjct: 135 CIHTYKGHTRGVNVLRFTPDGRWV-----VSGGEDNIVKVWDLTAGKLLTEFKSHEGQIQ 189 Query: 359 DLDYFLPGGNEQYIITGSLSGNARIWNLRTHKCIRVIKGTSITSGAGC 502 LD+ +E + TGS + W+L T + I G T+G C Sbjct: 190 SLDFH---PHEFLLATGSADRTVKFWDLETFELIG--SGGPETAGVRC 232 Score = 38.9 bits (89), Expect = 0.014 Identities = 23/65 (35%), Positives = 34/65 (52%) Frame = +2 Query: 56 KFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNP 235 +FK+H G IQ+L HP LL +G ++ +K WD E + + + A V L FNP Sbjct: 180 EFKSHEGQIQSLDFHPHEFLLATGSADR-TVKFWDLET-FELIGSGGPETAGVRCLSFNP 237 Query: 236 QNDSV 250 +V Sbjct: 238 DGKTV 242
>YH92_CAEEL (Q23256) Hypothetical WD-repeat protein ZC302.2| Length = 501 Score = 52.4 bits (124), Expect = 1e-06 Identities = 39/144 (27%), Positives = 60/144 (41%) Frame = +2 Query: 146 IKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPI 325 +K++D G CLRT H V FNPQ+ + ASA D ++WD L + Sbjct: 279 VKIFDVISG-ACLRTMRGHTNYVFCCSFNPQSSLI-----ASAGFDETVRVWDFKTGLCV 332 Query: 326 ATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNARIWNLRTHKCIRVIKGTSITSGAGCS 505 + S+ + + Y G + T S G R+W+ + C++ + T Sbjct: 333 KCIPAHSDPITSISYNHDGNT---MATSSYDGCIRVWDAASGSCLKTLVDTD-----HAP 384 Query: 506 VRVVYCSPDPPLLIRTFEDDSLGL 577 V V SP+ L+ D SL L Sbjct: 385 VTFVCFSPNGKYLLSAQLDSSLKL 408 Score = 33.5 bits (75), Expect = 0.57 Identities = 20/101 (19%), Positives = 48/101 (47%) Frame = +2 Query: 173 WTCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNG 352 ++ ++T + H V ++F+ +G + + D + K+W+ + + TL G Sbjct: 203 FSLVKTISGHTKSVSVIKFSYCGKYLG-----TGSADKQIKVWNTVDMTYLQTLASHQLG 257 Query: 353 LIDLDYFLPGGNEQYIITGSLSGNARIWNLRTHKCIRVIKG 475 + D + N Q+I + S +I+++ + C+R ++G Sbjct: 258 INDFSW---SSNSQFIASASDDTTVKIFDVISGACLRTMRG 295
>POF1_SCHPO (P87053) F-box/WD-repeat protein pof1 (Skp1-binding protein 1)| Length = 605 Score = 52.4 bits (124), Expect = 1e-06 Identities = 45/169 (26%), Positives = 77/169 (45%), Gaps = 2/169 (1%) Frame = +2 Query: 62 KAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQN 241 + H G + ++ + L+LSG + IK+W E TCL TF+AH V++L Sbjct: 389 RGHTGPVNSVRIIRDRGLVLSGS-DDSTIKIWSLETN-TCLHTFSAHIGPVQSL------ 440 Query: 242 DSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSG 421 ++ + S +LDG K WDI + TL G+ ++ + +I+G+ G Sbjct: 441 -ALADSRLFSCSLDGTIKQWDIEKKKCVHTLFGHIEGVWEI-----AADHLRLISGAHDG 494 Query: 422 NARIWNLRTHKCIRVIKGTS--ITSGAGCSVRVVYCSPDPPLLIRTFED 562 ++W +C+ +K S +TS A VV S D + + F + Sbjct: 495 VVKVW--EACECVHTLKNHSEPVTSVALGDCEVVSGSEDGKIYLWLFNN 541 Score = 48.5 bits (114), Expect = 2e-05 Identities = 36/144 (25%), Positives = 65/144 (45%), Gaps = 13/144 (9%) Frame = +2 Query: 158 DWEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLD 337 +W G + H V LQ + R AS + D ++W+++ +A L+ Sbjct: 258 NWRHGRCRQVVLSGHSDGVMCLQ-------LVRNILASGSYDATIRLWNLATFQQVALLE 310 Query: 338 CQSNGLIDLDYFLPGGNEQYIITGSLSGNARIWNLRTHKCIRVIKG------------TS 481 S+G+ L + ++ +I+GS+ RIWN RT +CI ++ G T Sbjct: 311 GHSSGVTCLQF-----DQCKLISGSMDKTIRIWNYRTSECISILHGHTDSVLCLTFDSTL 365 Query: 482 ITSG-AGCSVRVVYCSPDPPLLIR 550 + SG A C+V++ + S + +R Sbjct: 366 LVSGSADCTVKLWHFSGGKRITLR 389
>GBB3_CANFA (P79147) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 3 (Transducin beta chain 3) Length = 340 Score = 52.4 bits (124), Expect = 1e-06 Identities = 35/141 (24%), Positives = 65/141 (46%), Gaps = 2/141 (1%) Frame = +2 Query: 59 FKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQ 238 F H G +LAV P L +SG C+ KLWD +G TC +TF H++ + A+ F P Sbjct: 180 FVGHTGDCMSLAVSPDFKLFISGACDAS-AKLWDVREG-TCRQTFTGHESDINAICFFPN 237 Query: 239 NDSVGRTTFASAALDGKAKIWDISLILPIATLDCQS--NGLIDLDYFLPGGNEQYIITGS 412 +++ + + D +++D+ + +S G+ + + L G + + G Sbjct: 238 GEAI-----CTGSDDASCRLFDLRADQELTAYSDESIICGITSVAFSLSG---RLLFAGY 289 Query: 413 LSGNARIWNLRTHKCIRVIKG 475 N IW+ + + ++ G Sbjct: 290 DDFNCNIWDSMKGERVGILSG 310 Score = 33.1 bits (74), Expect = 0.75 Identities = 22/90 (24%), Positives = 41/90 (45%) Frame = +2 Query: 185 RTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDL 364 RT H AK+ A+ + + SA+ DGK +WD + + +S+ ++ Sbjct: 49 RTLRGHLAKIYAMHW-----ATDSKLLVSASQDGKLIVWDTYTTNKVHAIPLRSSWVMTC 103 Query: 365 DYFLPGGNEQYIITGSLSGNARIWNLRTHK 454 Y P GN ++ G L I++L++ + Sbjct: 104 AY-APSGN--FVACGGLDNMCSIYSLKSRE 130
>FBXW7_DROME (Q9VZF4) F-box/WD-repeat protein 7 (F-box and WD-40 domain protein 7)| (Protein archipelago) Length = 1326 Score = 52.0 bits (123), Expect = 2e-06 Identities = 37/149 (24%), Positives = 67/149 (44%), Gaps = 1/149 (0%) Frame = +2 Query: 50 VKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQF 229 V + H ++ + +H S + G +++WD E+G +CL H A V +Q+ Sbjct: 1068 VHTLQGHTSTVRCMHLHGSKVV---SGSRDATLRVWDIEQG-SCLHVLVGHLAAVRCVQY 1123 Query: 230 NPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITG 409 + + S A D KIW + TL +N + L + + ++++G Sbjct: 1124 DGK-------LIVSGAYDYMVKIWHPERQECLHTLQGHTNRVYSLQF-----DGLHVVSG 1171 Query: 410 SLSGNARIWNLRTHKCIRVIKG-TSITSG 493 SL + R+W++ T C + G S+TSG Sbjct: 1172 SLDTSIRVWDVETGNCKHTLMGHQSLTSG 1200 Score = 42.4 bits (98), Expect = 0.001 Identities = 27/122 (22%), Positives = 56/122 (45%), Gaps = 2/122 (1%) Frame = +2 Query: 116 LLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAK 295 L+ G ++K+W E+ CL T H +V +LQF+ + S +LD + Sbjct: 1127 LIVSGAYDYMVKIWHPERQ-ECLHTLQGHTNRVYSLQFDGLH-------VVSGSLDTSIR 1178 Query: 296 IWDISLILPIATLDCQSNGLIDLDYFLPGGN--EQYIITGSLSGNARIWNLRTHKCIRVI 469 +WD+ T +C+ L+ G + +++G+ ++W++ T +C++ + Sbjct: 1179 VWDVE------TGNCKHT-LMGHQSLTSGMELRQNILVSGNADSTVKVWDITTGQCLQTL 1231 Query: 470 KG 475 G Sbjct: 1232 SG 1233
>PRP46_ASPFU (Q4WT34) Pre-mRNA-splicing factor prp46 (Pre-mRNA-processing| protein 46) Length = 453 Score = 52.0 bits (123), Expect = 2e-06 Identities = 39/134 (29%), Positives = 62/134 (46%) Frame = +2 Query: 68 HNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDS 247 H ++ LAV P P L S G ++ ++K WD E +R ++ H + V L +P+ D Sbjct: 185 HISTVRGLAVSPRHPYLFSCGEDK-MVKCWDLETN-KVIRHYHGHLSGVYTLALHPRLDL 242 Query: 248 VGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNA 427 + + DG A++WD+ I L + DL + IITGSL Sbjct: 243 L-----VTGGRDGVARVWDMRTRSNIHVLSGHKGTVADLKC---QEADPQIITGSLDATV 294 Query: 428 RIWNLRTHKCIRVI 469 R+W+L K + V+ Sbjct: 295 RLWDLAAGKTMGVL 308 Score = 50.1 bits (118), Expect = 6e-06 Identities = 38/142 (26%), Positives = 62/142 (43%) Frame = +2 Query: 50 VKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQF 229 ++ H GW+++LAV P+ SG ++ IK+W+ G L T H + V L Sbjct: 137 MRVISGHLGWVRSLAVEPNNEWFASGAGDR-TIKIWNLATGALRL-TLTGHISTVRGLAV 194 Query: 230 NPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITG 409 +P++ + S D K WD+ I +G+ L ++TG Sbjct: 195 SPRHPYL-----FSCGEDKMVKCWDLETNKVIRHYHGHLSGVYTLALH---PRLDLLVTG 246 Query: 410 SLSGNARIWNLRTHKCIRVIKG 475 G AR+W++RT I V+ G Sbjct: 247 GRDGVARVWDMRTRSNIHVLSG 268 Score = 37.4 bits (85), Expect = 0.040 Identities = 27/106 (25%), Positives = 42/106 (39%) Frame = +2 Query: 158 DWEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLD 337 DW W +R + H V +L P N+ FAS A D KIW+++ TL Sbjct: 129 DWHPPWKLMRVISGHLGWVRSLAVEPNNE-----WFASGAGDRTIKIWNLATGALRLTL- 182 Query: 338 CQSNGLIDLDYFLPGGNEQYIITGSLSGNARIWNLRTHKCIRVIKG 475 + + + Y+ + + W+L T+K IR G Sbjct: 183 --TGHISTVRGLAVSPRHPYLFSCGEDKMVKCWDLETNKVIRHYHG 226
>LIS1_DROME (Q7KNS3) Lissencephaly-1 homolog (Lissencephaly1) (Dlis1) (DLis-1)| Length = 411 Score = 52.0 bits (123), Expect = 2e-06 Identities = 39/155 (25%), Positives = 69/155 (44%), Gaps = 15/155 (9%) Frame = +2 Query: 50 VKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQF 229 VK + H W++ + VH + + N I++W C H+ VE + + Sbjct: 228 VKTYTGHREWVRMVRVHIEGSIFATCS-NDQTIRVW-LTNSKDCKVELRDHEHTVECIAW 285 Query: 230 NPQ------NDSVGRTT---------FASAALDGKAKIWDISLILPIATLDCQSNGLIDL 364 P+ N++ G AS + D +IWD+S+ L + TL N + L Sbjct: 286 APEAAASAINEAAGADNKKGHHQGPFLASGSRDKTIRIWDVSVGLCLLTLSGHDNWVRGL 345 Query: 365 DYFLPGGNEQYIITGSLSGNARIWNLRTHKCIRVI 469 F PGG +Y+++ S R+W+LR +C++ + Sbjct: 346 A-FHPGG--KYLVSASDDKTIRVWDLRNKRCMKTL 377 Score = 46.6 bits (109), Expect = 7e-05 Identities = 28/90 (31%), Positives = 46/90 (51%), Gaps = 1/90 (1%) Frame = +2 Query: 44 EEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGL-IKLWDWEKGWTCLRTFNAHKAKVEA 220 E + K H +Q +A LL S C+ L IKLWD+++ + C++T + H V + Sbjct: 141 EYERSLKGHTDSVQDVAFDAQGKLLAS--CSADLSIKLWDFQQSYECIKTMHGHDHNVSS 198 Query: 221 LQFNPQNDSVGRTTFASAALDGKAKIWDIS 310 + F P D V SA+ D K+W+++ Sbjct: 199 VAFVPAGDYV-----LSASRDRTIKMWEVA 223 Score = 44.3 bits (103), Expect = 3e-04 Identities = 32/116 (27%), Positives = 51/116 (43%) Frame = +2 Query: 98 HPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAA 277 H P L SG ++ I++WD G CL T + H V L F+P G SA+ Sbjct: 306 HHQGPFLASGSRDK-TIRIWDVSVG-LCLLTLSGHDNWVRGLAFHP-----GGKYLVSAS 358 Query: 278 LDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNARIWNLR 445 D ++WD+ + TL + +D+ Y+I+GS+ ++W R Sbjct: 359 DDKTIRVWDLRNKRCMKTLYAHQHFCTSIDFHKA---HPYVISGSVDQTVKVWECR 411 Score = 44.3 bits (103), Expect = 3e-04 Identities = 33/137 (24%), Positives = 60/137 (43%), Gaps = 1/137 (0%) Frame = +2 Query: 68 HNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDS 247 H I + HP L++S I++WD+E G R+ H V+ + F+ Q Sbjct: 107 HRASITRVIFHPIFALMVSAS-EDATIRIWDFETG-EYERSLKGHTDSVQDVAFDAQGKL 164 Query: 248 VGRTTFASAALDGKAKIWDISLILP-IATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGN 424 + AS + D K+WD I T+ + + + F+P G+ Y+++ S Sbjct: 165 L-----ASCSADLSIKLWDFQQSYECIKTMHGHDHNVSSVA-FVPAGD--YVLSASRDRT 216 Query: 425 ARIWNLRTHKCIRVIKG 475 ++W + T C++ G Sbjct: 217 IKMWEVATGYCVKTYTG 233
>Y143_SYNY3 (P74442) Hypothetical WD-repeat protein slr0143| Length = 1191 Score = 52.0 bits (123), Expect = 2e-06 Identities = 34/120 (28%), Positives = 62/120 (51%) Frame = +2 Query: 80 IQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRT 259 I+++++HP+LP L +G QG + LW+++ T +R+ AH ++ LQ++P + Sbjct: 1000 IRSVSLHPTLPQLAAGD-EQGNLTLWNFD--GTLIRSIVAHGDRLNQLQYSPNGKYL--- 1053 Query: 260 TFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNARIWN 439 SA +G AKIW + L L + + +D + Q+I T + G R+W+ Sbjct: 1054 --LSAGREGTAKIWSVEGQL----LHTLKSDPLPIDQIAISPDSQWIATAASDGMVRLWD 1107 Score = 40.8 bits (94), Expect = 0.004 Identities = 32/133 (24%), Positives = 56/133 (42%), Gaps = 4/133 (3%) Frame = +2 Query: 50 VKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQF 229 ++ K H + +++ P +L S ++ ++LW W G T L H V+ QF Sbjct: 635 LQTLKGHQDSVYSVSFSPDGEILASTSRDR-TVRLWHWRSGKT-LAVLGGHTKSVDDAQF 692 Query: 230 NPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYF----LPGGNEQY 397 +P T S DG+ ++WD+ L + GL ++ +F P GN Sbjct: 693 SPDGQ-----TLVSVCRDGQIRLWDLDGNL------IRQFGLPEVAFFGVNWHPNGN--L 739 Query: 398 IITGSLSGNARIW 436 + + G R+W Sbjct: 740 LAVAADDGTVRLW 752
>TBL1X_HUMAN (O60907) F-box-like/WD-repeat protein TBL1X (Transducin beta-like| 1X protein) (Transducin-beta-like 1, X-linked) (SMAP55) Length = 526 Score = 52.0 bits (123), Expect = 2e-06 Identities = 37/148 (25%), Positives = 67/148 (45%), Gaps = 5/148 (3%) Frame = +2 Query: 50 VKKFKAHNGWIQALAVHPSLPLLLSGGCNQGL-IKLWDWEKGWTCLRTFNAHKAKVEALQ 226 VK F+ H + A+ PS LL S C+ + +K+W ++ C+ AH ++ ++ Sbjct: 354 VKTFQGHTNEVNAIKWDPSGMLLAS--CSDDMTLKIWSMKQE-VCIHDLQAHNKEIYTIK 410 Query: 227 FNPQNDSVGRTT----FASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQ 394 ++P + ASA+ D ++WDI + TL + + F P G + Sbjct: 411 WSPTGPATSNPNSNIMLASASFDSTVRLWDIERGVCTHTLTKHQEPVYSVA-FSPDG--K 467 Query: 395 YIITGSLSGNARIWNLRTHKCIRVIKGT 478 Y+ +GS IWN ++ + +GT Sbjct: 468 YLASGSFDKCVHIWNTQSGNLVHSYRGT 495
>GBB_DICDI (P36408) Guanine nucleotide-binding protein beta subunit| Length = 347 Score = 52.0 bits (123), Expect = 2e-06 Identities = 26/87 (29%), Positives = 47/87 (54%) Frame = +2 Query: 47 EVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQ 226 ++ +F HNG + +++V P +SG C+ KLWD G C++TF H+A + A+Q Sbjct: 183 KITEFSDHNGDVMSVSVSPDKNYFISGACD-ATAKLWDLRSG-KCVQTFTGHEADINAVQ 240 Query: 227 FNPQNDSVGRTTFASAALDGKAKIWDI 307 + P +F + + D +++DI Sbjct: 241 YFPNG-----LSFGTGSDDASCRLFDI 262 Score = 38.9 bits (89), Expect = 0.014 Identities = 28/149 (18%), Positives = 58/149 (38%), Gaps = 2/149 (1%) Frame = +2 Query: 35 LGLEEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQ--GLIKLWDWEKGWTCLRTFNAHKA 208 L +V + W+ A P+ + GG + + L E+ R N+H Sbjct: 92 LTTNKVHAIPLRSSWVMTCAYSPTANFVACGGLDNICSIYNLRSREQPIRVCRELNSHTG 151 Query: 209 KVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGN 388 + +F V +++ D +WD+ I + ++ + + Sbjct: 152 YLSCCRFLNDRQIV------TSSGDMTCILWDVENGTKITEFSDHNGDVMSVSV---SPD 202 Query: 389 EQYIITGSLSGNARIWNLRTHKCIRVIKG 475 + Y I+G+ A++W+LR+ KC++ G Sbjct: 203 KNYFISGACDATAKLWDLRSGKCVQTFTG 231 Score = 37.4 bits (85), Expect = 0.040 Identities = 32/134 (23%), Positives = 57/134 (42%) Frame = +2 Query: 53 KKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFN 232 ++ +H G++ ++ S G + LWD E G T + F+ H V ++ + Sbjct: 144 RELNSHTGYLSCCRFLNDRQIVTSSGDMTCI--LWDVENG-TKITEFSDHNGDVMSVSVS 200 Query: 233 PQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGS 412 P + F S A D AK+WD+ + T + + YF P G TGS Sbjct: 201 PD-----KNYFISGACDATAKLWDLRSGKCVQTFTGHEADINAVQYF-PNGLS--FGTGS 252 Query: 413 LSGNARIWNLRTHK 454 + R++++R + Sbjct: 253 DDASCRLFDIRADR 266 Score = 31.2 bits (69), Expect = 2.8 Identities = 23/90 (25%), Positives = 39/90 (43%) Frame = +2 Query: 185 RTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDL 364 R H AK+ A+ + N SA+ DGK +WD + + +S+ ++ Sbjct: 56 RNLKGHLAKIYAMHWAEDN-----VHLVSASQDGKLLVWDGLTTNKVHAIPLRSSWVMTC 110 Query: 365 DYFLPGGNEQYIITGSLSGNARIWNLRTHK 454 Y P N ++ G L I+NLR+ + Sbjct: 111 AY-SPTAN--FVACGGLDNICSIYNLRSRE 137
>GBB3_RAT (P52287) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 3 (Transducin beta chain 3) Length = 340 Score = 52.0 bits (123), Expect = 2e-06 Identities = 37/138 (26%), Positives = 65/138 (47%), Gaps = 2/138 (1%) Frame = +2 Query: 59 FKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQ 238 F H G +LAV P L +SG C+ KLWD +G TC +TF H++ + A+ F P Sbjct: 180 FVGHTGDCMSLAVSPDYKLFISGACDAS-AKLWDVREG-TCRQTFTGHESDINAICFFPN 237 Query: 239 NDSVGRTTFASAALDGKAKIWDISLILPIATLDCQS--NGLIDLDYFLPGGNEQYIITGS 412 +++ + + D +++D+ + +S G+ + + L G + + G Sbjct: 238 GEAI-----CTGSDDASCRLFDLRADQELTAYSHESIICGITSVAFSLSG---RLLFAGY 289 Query: 413 LSGNARIWNLRTHKCIRV 466 N +W+ + KC RV Sbjct: 290 DDFNCNVWD--SLKCERV 305 Score = 33.1 bits (74), Expect = 0.75 Identities = 22/90 (24%), Positives = 41/90 (45%) Frame = +2 Query: 185 RTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDL 364 RT H AK+ A+ + + SA+ DGK +WD + + +S+ ++ Sbjct: 49 RTLRGHLAKIYAMHW-----ATDSKLLVSASQDGKLIVWDTYTTNKVHAIPLRSSWVMTC 103 Query: 365 DYFLPGGNEQYIITGSLSGNARIWNLRTHK 454 Y P GN ++ G L I++L++ + Sbjct: 104 AY-APSGN--FVACGGLDNMCSIYSLKSRE 130
>GBB3_MOUSE (Q61011) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 3 (Transducin beta chain 3) Length = 340 Score = 52.0 bits (123), Expect = 2e-06 Identities = 37/138 (26%), Positives = 65/138 (47%), Gaps = 2/138 (1%) Frame = +2 Query: 59 FKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQ 238 F H G +LAV P L +SG C+ KLWD +G TC +TF H++ + A+ F P Sbjct: 180 FVGHTGDCMSLAVSPDYKLFISGACDAS-AKLWDVREG-TCRQTFTGHESDINAICFFPN 237 Query: 239 NDSVGRTTFASAALDGKAKIWDISLILPIATLDCQS--NGLIDLDYFLPGGNEQYIITGS 412 +++ + + D +++D+ + +S G+ + + L G + + G Sbjct: 238 GEAI-----CTGSDDASCRLFDLRADQELTAYSQESIICGITSVAFSLSG---RLLFAGY 289 Query: 413 LSGNARIWNLRTHKCIRV 466 N +W+ + KC RV Sbjct: 290 DDFNCNVWD--SLKCERV 305 Score = 35.0 bits (79), Expect = 0.20 Identities = 23/90 (25%), Positives = 41/90 (45%) Frame = +2 Query: 185 RTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDL 364 RT H AK+ A+ + + SA+ DGK +WD + + +S+ ++ Sbjct: 49 RTLRGHLAKIYAMHW-----ATDSKLLVSASQDGKLIVWDTYTTNKVHAIPLRSSWVMTC 103 Query: 365 DYFLPGGNEQYIITGSLSGNARIWNLRTHK 454 Y P GN ++ G L I+NL++ + Sbjct: 104 AY-APSGN--FVACGGLDNMCSIYNLKSRE 130
>EBI_DROME (Q95RJ9) F-box-like/WD repeat protein ebi| Length = 700 Score = 51.6 bits (122), Expect = 2e-06 Identities = 38/150 (25%), Positives = 68/150 (45%), Gaps = 5/150 (3%) Frame = +2 Query: 44 EEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGL-IKLWDWEKGWTCLRTFNAHKAKVEA 220 E +K FK H + A+ P LL S C+ + +K+W + C AH ++ Sbjct: 525 EPIKTFKGHTNEVNAIKWCPQGQLLAS--CSDDMTLKIWSMNRD-RCCHDLQAHSKEIYT 581 Query: 221 LQFNPQ----NDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGN 388 ++++P N+ ASA+ D ++WD+ I TL + + + F P G Sbjct: 582 IKWSPTGPGTNNPNTNLILASASFDSTVRLWDVERGSCIHTLTKHTEPVYSVA-FSPDG- 639 Query: 389 EQYIITGSLSGNARIWNLRTHKCIRVIKGT 478 +++ +GS IW+ +T + + KGT Sbjct: 640 -KHLASGSFDKCVHIWSTQTGQLVHSYKGT 668 Score = 32.7 bits (73), Expect = 0.98 Identities = 28/100 (28%), Positives = 39/100 (39%), Gaps = 16/100 (16%) Frame = +2 Query: 185 RTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDL 364 R H+++V +NP D + AS + D A+IWD+S + SN L+ Sbjct: 349 RVLRGHESEVFICAWNPSRDLL-----ASGSGDSTARIWDMS------DANTNSNQLVLR 397 Query: 365 DYFLPGGNE----------------QYIITGSLSGNARIW 436 GG E + TGS G ARIW Sbjct: 398 HCIQKGGAEVPSNKDVTSLDWNCDGSLLATGSYDGYARIW 437
>GBB3_HUMAN (P16520) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 3 (Transducin beta chain 3) Length = 340 Score = 51.6 bits (122), Expect = 2e-06 Identities = 34/141 (24%), Positives = 65/141 (46%), Gaps = 2/141 (1%) Frame = +2 Query: 59 FKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQ 238 F H G +LAV P L +SG C+ KLWD +G TC +TF H++ + A+ F P Sbjct: 180 FVGHTGDCMSLAVSPDFNLFISGACDAS-AKLWDVREG-TCRQTFTGHESDINAICFFPN 237 Query: 239 NDSVGRTTFASAALDGKAKIWDISLILPIATLDCQS--NGLIDLDYFLPGGNEQYIITGS 412 +++ + + D +++D+ + +S G+ + + L G + + G Sbjct: 238 GEAI-----CTGSDDASCRLFDLRADQELICFSHESIICGITSVAFSLSG---RLLFAGY 289 Query: 413 LSGNARIWNLRTHKCIRVIKG 475 N +W+ + + ++ G Sbjct: 290 DDFNCNVWDSMKSERVGILSG 310
>GRWD1_RAT (Q5XI13) Glutamate-rich WD repeat-containing protein 1| Length = 445 Score = 51.2 bits (121), Expect = 3e-06 Identities = 44/145 (30%), Positives = 66/145 (45%), Gaps = 7/145 (4%) Frame = +2 Query: 41 LEEVKKFKAHNGWIQALAVHPSLP-LLLSGGCNQGLIKLWDWEKG--WTC-LRTFNAHKA 208 ++ + F H G AL P +P LL+G C + I LW G W R F H Sbjct: 203 VKPIFSFAGHMGEGFALDWSPRVPGRLLTGDCQKN-IHLWTPTDGGSWNVDQRPFVGHTR 261 Query: 209 KVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLI---LPIATLDCQSNGLIDLDYFLP 379 VE LQ++P D+V FAS + D +IWDI + T +G D++ Sbjct: 262 SVEDLQWSPTEDTV----FASCSADASIRIWDIRAAPGKACMLTTAAAHDG--DVNVISW 315 Query: 380 GGNEQYIITGSLSGNARIWNLRTHK 454 E ++++G G ++W+LR K Sbjct: 316 SRREPFLLSGGDDGTLKVWDLRQFK 340
>KMHB_DICDI (P90648) Myosin heavy chain kinase B (EC 2.7.11.7) (MHCK B)| Length = 732 Score = 51.2 bits (121), Expect = 3e-06 Identities = 36/149 (24%), Positives = 66/149 (44%) Frame = +2 Query: 29 KTLGLEEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKA 208 K+ +E V+ K H G ++++ + L G + IK+WD +K C+ T H Sbjct: 488 KSQNMECVQTLKGHEGPVESICYNDQY---LFSGSSDHSIKVWDLKK-LRCIFTLEGHDK 543 Query: 209 KVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGN 388 V + N + S + D K+WD+ + TL+ + + L + Sbjct: 544 PVHTVLLNDKY-------LFSGSSDKTIKVWDLKTLECKYTLESHARAVKTLCI-----S 591 Query: 389 EQYIITGSLSGNARIWNLRTHKCIRVIKG 475 QY+ +GS ++W+L+T +C +KG Sbjct: 592 GQYLFSGSNDKTIKVWDLKTFRCNYTLKG 620
>GRWD1_MOUSE (Q810D6) Glutamate-rich WD repeat-containing protein 1 (Protein| A301) Length = 446 Score = 51.2 bits (121), Expect = 3e-06 Identities = 45/148 (30%), Positives = 70/148 (47%), Gaps = 10/148 (6%) Frame = +2 Query: 41 LEEVKKFKAHNGWIQALAVHPSLP-LLLSGGCNQGLIKLWDWEKG--WTC-LRTFNAHKA 208 ++ + F H G AL P +P LL+G C + + LW +G W R F H Sbjct: 204 IKPIFSFAGHMGEGFALDWSPRVPGRLLTGDCQKN-VHLWTPTEGGSWNVDQRPFVGHTR 262 Query: 209 KVEALQFNPQNDSVGRTTFASAALDGKAKIWDI------SLILPIATLDCQSNGLIDLDY 370 VE LQ++P D+V FAS + D +IWDI + +L AT +G D++ Sbjct: 263 SVEDLQWSPTEDTV----FASCSADASIRIWDIRAAPGKACMLTTAT---AHDG--DVNV 313 Query: 371 FLPGGNEQYIITGSLSGNARIWNLRTHK 454 E ++++G G ++W+LR K Sbjct: 314 ISWSRREPFLLSGGDDGALKVWDLRQFK 341
>PRP46_EMENI (Q5BE22) Pre-mRNA-splicing factor prp46 (Pre-mRNA-processing| protein 46) Length = 452 Score = 51.2 bits (121), Expect = 3e-06 Identities = 37/134 (27%), Positives = 63/134 (47%) Frame = +2 Query: 68 HNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDS 247 H ++ LAV P P L S G ++ ++K WD E +R ++ H + V L +P+ D Sbjct: 184 HISTVRGLAVSPRHPYLFSCGEDK-MVKCWDLETN-KVIRHYHGHLSGVYTLALHPRLDL 241 Query: 248 VGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNA 427 + + DG A++WD+ I L + + D+ + +ITGSL Sbjct: 242 L-----VTGGRDGVARVWDMRTRSNIHVLSGHTGTVADVQC---QEADPQVITGSLDATV 293 Query: 428 RIWNLRTHKCIRVI 469 R+W+L K + V+ Sbjct: 294 RLWDLAAGKTMGVL 307 Score = 50.4 bits (119), Expect = 5e-06 Identities = 44/166 (26%), Positives = 70/166 (42%) Frame = +2 Query: 50 VKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQF 229 ++ H GW+++LAV P+ SG ++ IK+W+ G L T H + V L Sbjct: 136 MRVISGHLGWVRSLAVEPNNEWFASGAGDR-TIKIWNLATGALRL-TLTGHISTVRGLAV 193 Query: 230 NPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITG 409 +P++ + S D K WD+ I +G+ L ++TG Sbjct: 194 SPRHPYL-----FSCGEDKMVKCWDLETNKVIRHYHGHLSGVYTLALH---PRLDLLVTG 245 Query: 410 SLSGNARIWNLRTHKCIRVIKGTSITSGAGCSVRVVYCSPDPPLLI 547 G AR+W++RT I V+ G + T V V C P +I Sbjct: 246 GRDGVARVWDMRTRSNIHVLSGHTGT------VADVQCQEADPQVI 285 Score = 35.8 bits (81), Expect = 0.12 Identities = 26/106 (24%), Positives = 42/106 (39%) Frame = +2 Query: 158 DWEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLD 337 +W W +R + H V +L P N+ FAS A D KIW+++ TL Sbjct: 128 EWHAPWKLMRVISGHLGWVRSLAVEPNNE-----WFASGAGDRTIKIWNLATGALRLTL- 181 Query: 338 CQSNGLIDLDYFLPGGNEQYIITGSLSGNARIWNLRTHKCIRVIKG 475 + + + Y+ + + W+L T+K IR G Sbjct: 182 --TGHISTVRGLAVSPRHPYLFSCGEDKMVKCWDLETNKVIRHYHG 225
>PRP17_YEAST (P40968) Pre-mRNA-splicing factor PRP17 (Cell division control| protein 40) Length = 455 Score = 50.8 bits (120), Expect = 3e-06 Identities = 27/85 (31%), Positives = 39/85 (45%) Frame = +2 Query: 50 VKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQF 229 ++ + H AL P L+ G N IK+WD+ + CLR F H ++AL+F Sbjct: 155 IRNYPGHPEGTTALKFLPKTGHLILSGGNDHTIKIWDFYHDYECLRDFQGHNKPIKALRF 214 Query: 230 NPQNDSVGRTTFASAALDGKAKIWD 304 S F S++ D KIWD Sbjct: 215 TEDCQS-----FLSSSFDRSVKIWD 234
>TBL1Y_HUMAN (Q9BQ87) F-box-like/WD-repeat protein TBL1Y (Transducin beta-like| 1Y protein) (Transducin-beta-like 1, Y-linked) Length = 522 Score = 50.8 bits (120), Expect = 3e-06 Identities = 36/148 (24%), Positives = 67/148 (45%), Gaps = 5/148 (3%) Frame = +2 Query: 50 VKKFKAHNGWIQALAVHPSLPLLLSGGCNQGL-IKLWDWEKGWTCLRTFNAHKAKVEALQ 226 VK F+ H + A+ PS LL S C+ + +K+W ++ C+ AH ++ ++ Sbjct: 352 VKTFQGHTNEVNAIKWDPSGMLLAS--CSDDMTLKIWSMKQD-ACVHDLQAHSKEIYTIK 408 Query: 227 FNPQNDSVGRTT----FASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQ 394 ++P + ASA+ D ++WD+ + TL + + F P G + Sbjct: 409 WSPTGPATSNPNSSIMLASASFDSTVRLWDVEQGVCTHTLMKHQEPVYSVA-FSPDG--K 465 Query: 395 YIITGSLSGNARIWNLRTHKCIRVIKGT 478 Y+ +GS IWN ++ + +GT Sbjct: 466 YLASGSFDKYVHIWNTQSGSLVHSYQGT 493
>GBLP_LEIMA (Q25306) Guanine nucleotide-binding protein beta subunit-like| protein (Antigen LACK) Length = 312 Score = 50.8 bits (120), Expect = 3e-06 Identities = 41/179 (22%), Positives = 75/179 (41%) Frame = +2 Query: 56 KFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNP 235 + + H G++ +++ + L+ ++ I++WD G C R F H V A+ F+P Sbjct: 60 RLEGHTGFVSCVSLAHATDYALTASWDRS-IRMWDLRNG-QCQRKFLKHTKDVLAVAFSP 117 Query: 236 QNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSL 415 + + SA D ++W+++ L + F P +++GS Sbjct: 118 DDRLI-----VSAGRDNVIRVWNVAGECMHEFLRDGHEDWVSSICFSPSLEHPIVVSGSW 172 Query: 416 SGNARIWNLRTHKCIRVIKGTSITSGAGCSVRVVYCSPDPPLLIRTFEDDSLGLCNSTT 592 ++WN+ KC R +KG S V V SPD L +D + L + +T Sbjct: 173 DNTIKVWNVNGGKCERTLKGHS------NYVSTVTVSPDGSLCASGGKDGAALLWDLST 225
>GBLP_LEIIN (P62884) Guanine nucleotide-binding protein beta subunit-like| protein (Antigen LACK) (LiP36) (p36Li) Length = 312 Score = 50.8 bits (120), Expect = 3e-06 Identities = 41/179 (22%), Positives = 75/179 (41%) Frame = +2 Query: 56 KFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNP 235 + + H G++ +++ + L+ ++ I++WD G C R F H V A+ F+P Sbjct: 60 RLEGHTGFVSCVSLAHATDYALTASWDRS-IRMWDLRNG-QCQRKFLKHTKDVLAVAFSP 117 Query: 236 QNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSL 415 + + SA D ++W+++ L + F P +++GS Sbjct: 118 DDRLI-----VSAGRDNVIRVWNVAGECMHEFLRDGHEDWVSSICFSPSLEHPIVVSGSW 172 Query: 416 SGNARIWNLRTHKCIRVIKGTSITSGAGCSVRVVYCSPDPPLLIRTFEDDSLGLCNSTT 592 ++WN+ KC R +KG S V V SPD L +D + L + +T Sbjct: 173 DNTIKVWNVNGGKCERTLKGHS------NYVSTVTVSPDGSLCASGGKDGAALLWDLST 225
>GBLP_LEICH (P62883) Guanine nucleotide-binding protein beta subunit-like| protein (Antigen LACK) Length = 312 Score = 50.8 bits (120), Expect = 3e-06 Identities = 41/179 (22%), Positives = 75/179 (41%) Frame = +2 Query: 56 KFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNP 235 + + H G++ +++ + L+ ++ I++WD G C R F H V A+ F+P Sbjct: 60 RLEGHTGFVSCVSLAHATDYALTASWDRS-IRMWDLRNG-QCQRKFLKHTKDVLAVAFSP 117 Query: 236 QNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSL 415 + + SA D ++W+++ L + F P +++GS Sbjct: 118 DDRLI-----VSAGRDNVIRVWNVAGECMHEFLRDGHEDWVSSICFSPSLEHPIVVSGSW 172 Query: 416 SGNARIWNLRTHKCIRVIKGTSITSGAGCSVRVVYCSPDPPLLIRTFEDDSLGLCNSTT 592 ++WN+ KC R +KG S V V SPD L +D + L + +T Sbjct: 173 DNTIKVWNVNGGKCERTLKGHS------NYVSTVTVSPDGSLCASGGKDGAALLWDLST 225
>HAT2_SCHPO (O94244) Histone acetyltransferase type B subunit 2 (EC 2.3.1.48)| Length = 430 Score = 50.4 bits (119), Expect = 5e-06 Identities = 36/129 (27%), Positives = 61/129 (47%) Frame = +2 Query: 44 EEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEAL 223 E K +AH+ I A+A++P LL+ + LWD + L T H+ +V L Sbjct: 272 EAPKVIQAHSKAINAVAINPFNDYLLATASADKTVALWDLRNPYQRLHTLEGHEDEVYGL 331 Query: 224 QFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYII 403 +++P ++ + AS++ D + IWD+ I T + +G +L F+ GG+ I Sbjct: 332 EWSPHDEPI----LASSSTDRRVCIWDLEKIGEEQTPEDAEDGSPEL-LFMHGGHTNRIS 386 Query: 404 TGSLSGNAR 430 S N R Sbjct: 387 EFSWCPNER 395 Score = 29.6 bits (65), Expect = 8.3 Identities = 33/142 (23%), Positives = 60/142 (42%), Gaps = 14/142 (9%) Frame = +2 Query: 62 KAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWE-KGWTCLRT--------FNAHKAKV 214 K H L +P+LP L+ G +I LWD + + +T T ++ H V Sbjct: 179 KGHTAEGFGLCWNPNLPGNLATGAEDQVICLWDVQTQSFTSSETKVISPIAKYHRHTDIV 238 Query: 215 EALQFNPQNDSVGRTTFASAALDGKAKIWDISL-----ILPIATLDCQSNGLIDLDYFLP 379 +QF+PQ++++ AS + D +I D L + ++ + ++ F Sbjct: 239 NDVQFHPQHEAL----LASVSDDCTLQIHDTRLNPEEEAPKVIQAHSKAINAVAINPF-- 292 Query: 380 GGNEQYIITGSLSGNARIWNLR 445 N+ + T S +W+LR Sbjct: 293 --NDYLLATASADKTVALWDLR 312
>MSI1_LYCES (O22466) WD-40 repeat protein MSI1| Length = 424 Score = 50.4 bits (119), Expect = 5e-06 Identities = 34/117 (29%), Positives = 57/117 (48%) Frame = +2 Query: 50 VKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQF 229 ++ AH + LA +P +++ G +KL+D K T L T + HK +V + + Sbjct: 266 IQSVVAHQSEVNCLAFNPFNEWVVATGSTDKTVKLFDLRKISTALHTLDCHKEEVFQVGW 325 Query: 230 NPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYI 400 NP+N+ T AS L + +WD+S I T + +G +L F+ GG+ I Sbjct: 326 NPKNE----TILASCCLGRRLMVWDLSRIDEEQTPEDAEDGPPEL-LFIHGGHTSKI 377 Score = 44.7 bits (104), Expect = 2e-04 Identities = 36/144 (25%), Positives = 64/144 (44%), Gaps = 3/144 (2%) Frame = +2 Query: 20 AXCKTLGLEEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTC--LRTF 193 A K LE ++ FK H G ++ +A H L + + +WD +++ Sbjct: 210 ATPKNKALEAMQIFKVHEGVVEDVAWHLRHEYLFGSVGDDQYLHVWDLRTPSVTKPIQSV 269 Query: 194 NAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLI-LPIATLDCQSNGLIDLDY 370 AH+++V L FNP N+ V A+ + D K++D+ I + TLDC + + + Sbjct: 270 VAHQSEVNCLAFNPFNEWV----VATGSTDKTVKLFDLRKISTALHTLDCHKEEVFQVGW 325 Query: 371 FLPGGNEQYIITGSLSGNARIWNL 442 NE + + L +W+L Sbjct: 326 --NPKNETILASCCLGRRLMVWDL 347
>TAF5_YEAST (P38129) Transcription initiation factor TFIID subunit 5| (TBP-associated factor 5) (TBP-associated factor 90 kDa) (TAFII-90) Length = 798 Score = 50.1 bits (118), Expect = 6e-06 Identities = 38/141 (26%), Positives = 63/141 (44%) Frame = +2 Query: 53 KKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFN 232 K H+G + + + P LLSG ++ ++LW + T L ++ H V + F+ Sbjct: 519 KTLVGHSGTVYSTSFSPDNKYLLSGSEDK-TVRLWSMDTH-TALVSYKGHNHPVWDVSFS 576 Query: 233 PQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGS 412 P FA+A+ D A++W I P+ N +D F P G Y+ TGS Sbjct: 577 PLGHY-----FATASHDQTARLWSCDHIYPLRIFAGHLND-VDCVSFHPNGC--YVFTGS 628 Query: 413 LSGNARIWNLRTHKCIRVIKG 475 R+W++ T +R+ G Sbjct: 629 SDKTCRMWDVSTGDSVRLFLG 649 Score = 29.6 bits (65), Expect = 8.3 Identities = 20/88 (22%), Positives = 37/88 (42%) Frame = +2 Query: 44 EEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEAL 223 + V+ F H + ++AV P LS G G+I +WD G + K + +L Sbjct: 642 DSVRLFLGHTAPVISIAVCPD-GRWLSTGSEDGIINVWDIGTGKRLKQMRGHGKNAIYSL 700 Query: 224 QFNPQNDSVGRTTFASAALDGKAKIWDI 307 ++ + + S D ++WD+ Sbjct: 701 SYSKEGN-----VLISGGADHTVRVWDL 723
>TAF73_SCHPO (O74319) Transcription initiation factor TFIID subunit taf73| (Transcription initiation factor TFIID 73 kDa subunit) (TAFII-73) Length = 642 Score = 50.1 bits (118), Expect = 6e-06 Identities = 39/146 (26%), Positives = 66/146 (45%), Gaps = 1/146 (0%) Frame = +2 Query: 68 HNGWIQALAVHPSLPLLLSGGCNQ-GLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQND 244 H + +++ P +LS C++ G +LW + T ++ + H A + +QF+P Sbjct: 402 HTRPVFGVSISPQKEFILS--CSEDGFTRLWSKDTKSTIVK-YAGHNAPIWDVQFSPFG- 457 Query: 245 SVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGN 424 FA+A+ D A++WD+ P+ N +D F P N Y+ TGS Sbjct: 458 ----YYFATASHDQTARLWDVEHAAPLRVFVGHQND-VDCVSFHP--NAAYLATGSSDHT 510 Query: 425 ARIWNLRTHKCIRVIKGTSITSGAGC 502 R+W++RT +RV A C Sbjct: 511 TRMWDVRTGGTVRVFNAHHSPVSALC 536
>PRP46_DEBHA (Q6BU94) Pre-mRNA-splicing factor PRP46 (Pre-mRNA-processing| protein 46) Length = 417 Score = 49.7 bits (117), Expect = 8e-06 Identities = 34/132 (25%), Positives = 62/132 (46%) Frame = +2 Query: 47 EVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQ 226 +++ + H G I A+A+HP L LL +GG +I++WD + T + + H++ + ++ Sbjct: 203 QIRNYHGHVGGIYAMALHPELDLLFTGG-RDSVIRVWDL-RSRTEIMVLSGHRSDITSIA 260 Query: 227 FNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIIT 406 +G ++++D ++WDI L S I L P E + + Sbjct: 261 -----SQIGDPQIITSSMDATIRLWDIRKATTQLALTHHSKS-IRLMAMHP--QEMTMCS 312 Query: 407 GSLSGNARIWNL 442 G SGN + W L Sbjct: 313 GDTSGNLKEWLL 324 Score = 40.4 bits (93), Expect = 0.005 Identities = 31/126 (24%), Positives = 56/126 (44%), Gaps = 4/126 (3%) Frame = +2 Query: 80 IQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCL----RTFNAHKAKVEALQFNPQNDS 247 +++LAV P L SG ++ +K WD E+ + L R ++ H + A+ +P+ D Sbjct: 167 VRSLAVSSRYPYLFSGSEDK-TVKCWDLERTNSLLGCQIRNYHGHVGGIYAMALHPELDL 225 Query: 248 VGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNA 427 + + D ++WD+ I L S D+ + IIT S+ Sbjct: 226 L-----FTGGRDSVIRVWDLRSRTEIMVL---SGHRSDITSIASQIGDPQIITSSMDATI 277 Query: 428 RIWNLR 445 R+W++R Sbjct: 278 RLWDIR 283 Score = 37.7 bits (86), Expect = 0.030 Identities = 40/154 (25%), Positives = 60/154 (38%), Gaps = 9/154 (5%) Frame = +2 Query: 65 AHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQND 244 AH GW+++ V P G + IK+WD T H V +L + + Sbjct: 119 AHQGWVRSCTVDPVTNKWFVTGSSDSTIKIWDL-ASLNLKATITGHIMGVRSLAVSSRYP 177 Query: 245 SVGRTTFASAALDGKAKIWDISLILPIATLDCQ---SNGLIDLDYFLPGGNE-QYIITGS 412 + S + D K WD+ + L CQ +G + Y + E + TG Sbjct: 178 YL-----FSGSEDKTVKCWDLERTNSL--LGCQIRNYHGHVGGIYAMALHPELDLLFTGG 230 Query: 413 LSGNARIWNLRTHKCIRVIKG-----TSITSGAG 499 R+W+LR+ I V+ G TSI S G Sbjct: 231 RDSVIRVWDLRSRTEIMVLSGHRSDITSIASQIG 264
>TAF5L_MOUSE (Q91WQ5) TAF5-like RNA polymerase II p300/CBP-associated| factor-associated factor 65 kDa subunit 5L (PCAF-associated factor 65 beta) (PAF65-beta) Length = 589 Score = 49.3 bits (116), Expect = 1e-05 Identities = 33/141 (23%), Positives = 65/141 (46%) Frame = +2 Query: 59 FKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQ 238 + H + + HP+ L +G ++ ++LW ++G +R F H+ V +L F+P Sbjct: 422 YAGHLADVDCVKFHPNSNYLATGSTDK-TVRLWSAQQG-NSVRLFTGHRGPVLSLSFSPN 479 Query: 239 NDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLS 418 + ASA D + K+WD++ L ++ + L + G I + S+ Sbjct: 480 GKYL-----ASAGEDQRLKLWDLASGTLFKELRGHTDSITSLAFSPDSG---LIASASMD 531 Query: 419 GNARIWNLRTHKCIRVIKGTS 481 + R+W++R+ C G+S Sbjct: 532 NSVRVWDIRSTCCNTPADGSS 552 Score = 47.0 bits (110), Expect = 5e-05 Identities = 28/86 (32%), Positives = 44/86 (51%) Frame = +2 Query: 50 VKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQF 229 V+ F H G + +L+ P+ L S G +Q L KLWD G T + H + +L F Sbjct: 461 VRLFTGHRGPVLSLSFSPNGKYLASAGEDQRL-KLWDLASG-TLFKELRGHTDSITSLAF 518 Query: 230 NPQNDSVGRTTFASAALDGKAKIWDI 307 +P + + ASA++D ++WDI Sbjct: 519 SPDSGLI-----ASASMDNSVRVWDI 539 Score = 37.0 bits (84), Expect = 0.052 Identities = 35/144 (24%), Positives = 59/144 (40%), Gaps = 1/144 (0%) Frame = +2 Query: 47 EVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGL-IKLWDWEKGWTCLRTFNAHKAKVEAL 223 E+K + H G + + LLS C++ + I+ WD +T + H V + Sbjct: 334 EMKILRGHCGPVYSTRFLADSSGLLS--CSEDMSIRYWDLGS-FTNTVLYQGHAYPVWDV 390 Query: 224 QFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYII 403 +P + FAS + D A++W P L + L D+D N Y+ Sbjct: 391 DISPFS-----LYFASGSHDRTARLWSFDRTYP---LRIYAGHLADVDCVKFHPNSNYLA 442 Query: 404 TGSLSGNARIWNLRTHKCIRVIKG 475 TGS R+W+ + +R+ G Sbjct: 443 TGSTDKTVRLWSAQQGNSVRLFTG 466
>TAF5L_HUMAN (O75529) TAF5-like RNA polymerase II p300/CBP-associated| factor-associated factor 65 kDa subunit 5L (PCAF-associated factor 65 beta) (PAF65-beta) Length = 589 Score = 49.3 bits (116), Expect = 1e-05 Identities = 33/103 (32%), Positives = 50/103 (48%) Frame = +2 Query: 50 VKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQF 229 V+ F H G + +LA P+ L S G +Q L KLWD G T + H + +L F Sbjct: 461 VRLFTGHRGPVLSLAFSPNGKYLASAGEDQRL-KLWDLASG-TLYKELRGHTDNITSLTF 518 Query: 230 NPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLI 358 +P + + ASA++D ++WDI A D S+ L+ Sbjct: 519 SPDSGLI-----ASASMDNSVRVWDIRNTYCSAPADGSSSELV 556 Score = 38.9 bits (89), Expect = 0.014 Identities = 36/144 (25%), Positives = 59/144 (40%), Gaps = 1/144 (0%) Frame = +2 Query: 47 EVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGL-IKLWDWEKGWTCLRTFNAHKAKVEAL 223 E+K + H G + + LLS C++ + I+ WD +T + H V L Sbjct: 334 EMKILRGHCGPVYSTRFLADSSGLLS--CSEDMSIRYWDLGS-FTNTVLYQGHAYPVWDL 390 Query: 224 QFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYII 403 +P + FAS + D A++W P L + L D+D N Y+ Sbjct: 391 DISPYS-----LYFASGSHDRTARLWSFDRTYP---LRIYAGHLADVDCVKFHPNSNYLA 442 Query: 404 TGSLSGNARIWNLRTHKCIRVIKG 475 TGS R+W+ + +R+ G Sbjct: 443 TGSTDKTVRLWSAQQGNSVRLFTG 466
>YJL2_YEAST (P47025) Hypothetical 80.0 kDa Trp-Asp repeats-containing protein| in ASF1-CCT7 intergenic region Length = 714 Score = 49.3 bits (116), Expect = 1e-05 Identities = 42/150 (28%), Positives = 62/150 (41%), Gaps = 17/150 (11%) Frame = +2 Query: 50 VKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTF------------ 193 V F+AH + AL++ PS L G I+ WD G CL+T Sbjct: 495 VHTFEAHTDEVTALSLDPSF---LVSGSQDRTIRQWDLRSG-KCLQTIDLSFANVLTTST 550 Query: 194 NAHKAKVEALQFNPQNDSVGRTTFASAAL-----DGKAKIWDISLILPIATLDCQSNGLI 358 N +K L + S+G AAL DG ++WD+ I TL ++ + Sbjct: 551 NVDLSKSTLLTQRNERPSIGALQSFDAALATGTKDGVVRLWDLRSGKVIRTLKGHTDAIT 610 Query: 359 DLDYFLPGGNEQYIITGSLSGNARIWNLRT 448 L + + ++TGS RIW+LRT Sbjct: 611 SLKF-----DSACLVTGSYDRTVRIWDLRT 635 Score = 40.0 bits (92), Expect = 0.006 Identities = 37/138 (26%), Positives = 56/138 (40%), Gaps = 24/138 (17%) Frame = +2 Query: 179 CLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQ----- 343 C+ TF AH +V AL +P + S + D + WD+ + T+D Sbjct: 494 CVHTFEAHTDEVTALSLDP-------SFLVSGSQDRTIRQWDLRSGKCLQTIDLSFANVL 546 Query: 344 ---SNGLIDLDYFLPGGNEQYII-----------TGSLSGNARIWNLRTHKCIRVIKG-- 475 +N + L NE+ I TG+ G R+W+LR+ K IR +KG Sbjct: 547 TTSTNVDLSKSTLLTQRNERPSIGALQSFDAALATGTKDGVVRLWDLRSGKVIRTLKGHT 606 Query: 476 ---TSITSGAGCSVRVVY 520 TS+ + C V Y Sbjct: 607 DAITSLKFDSACLVTGSY 624
>WD51B_HUMAN (Q8TC44) WD-repeat protein 51B| Length = 478 Score = 48.9 bits (115), Expect = 1e-05 Identities = 38/137 (27%), Positives = 60/137 (43%), Gaps = 1/137 (0%) Frame = +2 Query: 68 HNGWIQALAVHPSLPLLLSGGCNQG-LIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQND 244 H W++ P L++S C++ IK+WD C+ F+ + FNP Sbjct: 143 HTHWVRCAKFSPDGRLIVS--CSEDKTIKIWDTTNK-QCVNNFSDSVGFANFVDFNPSG- 198 Query: 245 SVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGN 424 T ASA D K+WD+ + + S G ++ F P GN Y+IT S G Sbjct: 199 ----TCIASAGSDQTVKVWDVRVNKLLQHYQVHSGG-VNCISFHPSGN--YLITASSDGT 251 Query: 425 ARIWNLRTHKCIRVIKG 475 +I +L + I ++G Sbjct: 252 LKILDLLEGRLIYTLQG 268 Score = 32.7 bits (73), Expect = 0.98 Identities = 21/84 (25%), Positives = 39/84 (46%) Frame = +2 Query: 50 VKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQF 229 ++ ++ H+G + ++ HPS L++ + G +K+ D +G + T H V + F Sbjct: 221 LQHYQVHSGGVNCISFHPSGNYLITAS-SDGTLKILDLLEG-RLIYTLQGHTGPVFTVSF 278 Query: 230 NPQNDSVGRTTFASAALDGKAKIW 301 S G FAS D + +W Sbjct: 279 -----SKGGELFASGGADTQVLLW 297
>GBB1_DROME (P26308) Guanine nucleotide-binding protein beta subunit 1| Length = 340 Score = 48.9 bits (115), Expect = 1e-05 Identities = 27/87 (31%), Positives = 45/87 (51%) Frame = +2 Query: 47 EVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQ 226 +V F H G + AL++ P +SG C+ KLWD +G C +TF H++ + A+ Sbjct: 176 QVTSFLGHTGDVMALSLAPQCKTFVSGACDAS-AKLWDIREG-VCKQTFPGHESDINAVT 233 Query: 227 FNPQNDSVGRTTFASAALDGKAKIWDI 307 F P + FA+ + D +++DI Sbjct: 234 FFPNGQA-----FATGSDDATCRLFDI 255 Score = 38.9 bits (89), Expect = 0.014 Identities = 27/90 (30%), Positives = 43/90 (47%) Frame = +2 Query: 185 RTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDL 364 RT H AK+ A+ + NDS SA+ DGK +WD + + +S+ ++ Sbjct: 49 RTLRGHLAKIYAMHWG--NDS---RNLVSASQDGKLIVWDSHTTNKVHAIPLRSSWVMTC 103 Query: 365 DYFLPGGNEQYIITGSLSGNARIWNLRTHK 454 Y P G+ Y+ G L I+NL+T + Sbjct: 104 AY-APSGS--YVACGGLDNMCSIYNLKTRE 130
>GBB1_BRARE (Q6PH57) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 340 Score = 48.1 bits (113), Expect = 2e-05 Identities = 25/88 (28%), Positives = 47/88 (53%) Frame = +2 Query: 44 EEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEAL 223 ++ F H G + +L++ P L +SG C+ KLWD +G C +TF H++ + A+ Sbjct: 175 QQTTTFAGHTGDVMSLSLAPDTRLFVSGACDAS-AKLWDVREG-MCRQTFTGHESDINAI 232 Query: 224 QFNPQNDSVGRTTFASAALDGKAKIWDI 307 F P ++ FA+ + D +++D+ Sbjct: 233 CFFPNGNA-----FATGSDDATCRLFDL 255 Score = 38.1 bits (87), Expect = 0.023 Identities = 26/90 (28%), Positives = 41/90 (45%) Frame = +2 Query: 185 RTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDL 364 RT H AK+ A+ + + SA+ DGK IWD + + +S+ ++ Sbjct: 49 RTLRGHLAKIYAMHWGTDS-----RLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTC 103 Query: 365 DYFLPGGNEQYIITGSLSGNARIWNLRTHK 454 Y P GN Y+ G L I+NL+T + Sbjct: 104 AY-APSGN--YVACGGLDNICSIYNLKTRE 130
>ATG16_XENTR (Q5I0B9) Autophagy-related protein 16 (APG16-like 1)| Length = 537 Score = 48.1 bits (113), Expect = 2e-05 Identities = 42/158 (26%), Positives = 72/158 (45%), Gaps = 2/158 (1%) Frame = +2 Query: 50 VKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLR--TFNAHKAKVEAL 223 V F AH+G + A+ P LL +GG ++ +KLWD G C + A + ++ Sbjct: 245 VYSFDAHDGEVNAVRFSPGSRLLATGGMDRR-VKLWD-VIGNKCEAKGSLTGSNAGITSI 302 Query: 224 QFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYII 403 +F DS G A A+ D ++IW + TL S ++ + L I+ Sbjct: 303 EF----DSAGSYLLA-ASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNAR---IV 354 Query: 404 TGSLSGNARIWNLRTHKCIRVIKGTSITSGAGCSVRVV 517 +GS ++W+LR+ CI+ + S + C+ + V Sbjct: 355 SGSHDRTLKLWDLRSKVCIKTVFAGSSCNDIVCTEQCV 392 Score = 38.5 bits (88), Expect = 0.018 Identities = 24/104 (23%), Positives = 50/104 (48%), Gaps = 2/104 (1%) Frame = +2 Query: 176 TCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDI--SLILPIATLDCQSN 349 T + +F+AH +V A++F+P G A+ +D + K+WD+ + +L + Sbjct: 243 TAVYSFDAHDGEVNAVRFSP-----GSRLLATGGMDRRVKLWDVIGNKCEAKGSLTGSNA 297 Query: 350 GLIDLDYFLPGGNEQYIITGSLSGNARIWNLRTHKCIRVIKGTS 481 G+ +++ G Y++ S +RIW + ++ + G S Sbjct: 298 GITSIEFDSAG---SYLLAASNDFASRIWTVDDYRLRHTLTGHS 338
>HAT2_CRYNE (Q5KDT9) Histone acetyltransferase type B subunit 2 (EC 2.3.1.48)| Length = 435 Score = 48.1 bits (113), Expect = 2e-05 Identities = 35/109 (32%), Positives = 50/109 (45%) Frame = +2 Query: 62 KAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQN 241 + HN I ++ PS L G + I LWD K T +F AH V L ++P + Sbjct: 283 QGHNAEINCISFAPSSEYLFLTGSSDNTIALWDLRKLSTKHHSFEAHTNDVLQLSWSPTS 342 Query: 242 DSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGN 388 FASA+ D + IWD+ I T D +G +L F+ GG+ Sbjct: 343 P----VHFASASADRRVHIWDLDAIGAEQTPDDAEDGPPEL-LFVHGGH 386 Score = 35.4 bits (80), Expect = 0.15 Identities = 24/137 (17%), Positives = 56/137 (40%), Gaps = 3/137 (2%) Frame = +2 Query: 41 LEEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRT--FNAHKAKV 214 L+ ++ + H+ ++ + HP + + G I +WD T + H A++ Sbjct: 230 LQPLRLYTGHSAYVADVEWHPKNENMFGSVSDDGQIMIWDTRSDNTAKASSQVQGHNAEI 289 Query: 215 EALQFNPQNDSVGRTTFASAALDGKAKIWDI-SLILPIATLDCQSNGLIDLDYFLPGGNE 391 + F P ++ + F + + D +WD+ L + + +N ++ L + + Sbjct: 290 NCISFAPSSEYL----FLTGSSDNTIALWDLRKLSTKHHSFEAHTNDVLQLSW--SPTSP 343 Query: 392 QYIITGSLSGNARIWNL 442 + + S IW+L Sbjct: 344 VHFASASADRRVHIWDL 360
>HAT2_ASPOR (Q2UA71) Histone acetyltransferase type B subunit 2 (EC 2.3.1.48)| Length = 436 Score = 48.1 bits (113), Expect = 2e-05 Identities = 40/125 (32%), Positives = 55/125 (44%) Frame = +2 Query: 68 HNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDS 247 H I A+A +P+ +L+ G I LWD T L T H V +L ++P +S Sbjct: 285 HRDAINAIAFNPAAETVLATGSADKSIGLWDLRNLKTKLHTLECHTDSVTSLSWHPFEES 344 Query: 248 VGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNA 427 V ASA+ D K WD+S T D +G +L F+ GG+ I S Sbjct: 345 V----LASASYDRKIMFWDLSRSGEEQTPDDAQDGPPEL-LFMHGGHTNRISDFS----- 394 Query: 428 RIWNL 442 WNL Sbjct: 395 --WNL 397 Score = 38.1 bits (87), Expect = 0.023 Identities = 37/129 (28%), Positives = 56/129 (43%), Gaps = 7/129 (5%) Frame = +2 Query: 200 HKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISL--ILPIATLDCQSN--GLIDLD 367 HK +V ++ PQN +V A+ DG+ IWD S LP T++ Q G Sbjct: 137 HKGEVNKARYQPQNPNV----IATMCTDGRVMIWDRSKHPSLPTGTVNPQMELLGHTKEG 192 Query: 368 YFLPGGNEQ--YIITGSLSGNARIWNLRTH-KCIRVIKGTSITSGAGCSVRVVYCSPDPP 538 + L +++TGS R+W+L T+ K + +K + + V V P Sbjct: 193 FGLSWSPHTAGHLVTGSEDKTVRLWDLTTYTKGNKALKPSRTYTHHSSIVNDVQYHPLHS 252 Query: 539 LLIRTFEDD 565 LI T DD Sbjct: 253 SLIGTVSDD 261
>PRP46_SCHPO (O13615) Pre-mRNA-splicing factor prp46 (Pre-mRNA-processing| protein 5) (Complexed with cdc5 protein 1) Length = 473 Score = 48.1 bits (113), Expect = 2e-05 Identities = 36/136 (26%), Positives = 62/136 (45%), Gaps = 2/136 (1%) Frame = +2 Query: 68 HNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDS 247 H ++ LAV P P L S G ++ ++K WD E +R ++ H + V AL+ +P D Sbjct: 204 HIATVRGLAVSPRHPYLFSCGEDK-MVKCWDLETN-KVIRHYHGHLSGVYALKLHPTLD- 260 Query: 248 VGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDL--DYFLPGGNEQYIITGSLSG 421 +A D A++WD+ + L + + L F P ++TGS+ Sbjct: 261 ----VLVTAGRDAVARVWDMRTRQNVHVLSGHKSTVASLAVQEFDP-----QVVTGSMDS 311 Query: 422 NARIWNLRTHKCIRVI 469 R+W+L K + + Sbjct: 312 TIRLWDLAAGKTLTTL 327 Score = 43.9 bits (102), Expect = 4e-04 Identities = 35/146 (23%), Positives = 59/146 (40%) Frame = +2 Query: 50 VKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQF 229 ++ H GW++ + V P +G ++ IK+WD G L T H A V L Sbjct: 156 MRVISGHLGWVRCVDVEPGNQWFCTGAGDR-TIKIWDLASGVLKL-TLTGHIATVRGLAV 213 Query: 230 NPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITG 409 +P++ + S D K WD+ I +G+ L ++T Sbjct: 214 SPRHPYL-----FSCGEDKMVKCWDLETNKVIRHYHGHLSGVYALKLH---PTLDVLVTA 265 Query: 410 SLSGNARIWNLRTHKCIRVIKGTSIT 487 AR+W++RT + + V+ G T Sbjct: 266 GRDAVARVWDMRTRQNVHVLSGHKST 291 Score = 35.8 bits (81), Expect = 0.12 Identities = 25/106 (23%), Positives = 41/106 (38%) Frame = +2 Query: 158 DWEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLD 337 +W WT +R + H V + P G F + A D KIWD++ + TL Sbjct: 148 EWHAPWTLMRVISGHLGWVRCVDVEP-----GNQWFCTGAGDRTIKIWDLASGVLKLTL- 201 Query: 338 CQSNGLIDLDYFLPGGNEQYIITGSLSGNARIWNLRTHKCIRVIKG 475 + + + Y+ + + W+L T+K IR G Sbjct: 202 --TGHIATVRGLAVSPRHPYLFSCGEDKMVKCWDLETNKVIRHYHG 245
>LIN53_CAEEL (P90916) Probable histone-binding protein lin-53 (Abnormal cell| lineage protein 53) Length = 417 Score = 48.1 bits (113), Expect = 2e-05 Identities = 32/120 (26%), Positives = 58/120 (48%) Frame = +2 Query: 65 AHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQND 244 AH+ + LA +P +L+ G + LWD L +F +H+ ++ +Q++P N+ Sbjct: 263 AHSAEVNCLAFNPYSEFILATGSADKTVALWDLRNLRMKLHSFESHRDEIFQVQWSPHNE 322 Query: 245 SVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGN 424 T AS+ D + +WD+S I + + +G +L F+ GG+ I S + N Sbjct: 323 ----TILASSGTDKRLHVWDLSKIGEDQSAEDAEDGPPEL-LFIHGGHTAKISDFSWNPN 377 Score = 32.7 bits (73), Expect = 0.98 Identities = 25/129 (19%), Positives = 54/129 (41%), Gaps = 1/129 (0%) Frame = +2 Query: 59 FKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQ 238 FK H ++ +A H + + + +WD T +AH A+V L FNP Sbjct: 218 FKGHESVVEDVAWHVLHDGVFGSVGDDKKLLIWDVRTS-TPGHCIDAHSAEVNCLAFNPY 276 Query: 239 NDSVGRTTFASAALDGKAKIWDI-SLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSL 415 ++ + A+ + D +WD+ +L + + + + + + + + NE + + Sbjct: 277 SEFI----LATGSADKTVALWDLRNLRMKLHSFESHRDEIFQVQW--SPHNETILASSGT 330 Query: 416 SGNARIWNL 442 +W+L Sbjct: 331 DKRLHVWDL 339
>GBB1_RAT (P54311) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 339 Score = 48.1 bits (113), Expect = 2e-05 Identities = 25/88 (28%), Positives = 47/88 (53%) Frame = +2 Query: 44 EEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEAL 223 ++ F H G + +L++ P L +SG C+ KLWD +G C +TF H++ + A+ Sbjct: 174 QQTTTFTGHTGDVMSLSLAPDTRLFVSGACDAS-AKLWDVREG-MCRQTFTGHESDINAI 231 Query: 224 QFNPQNDSVGRTTFASAALDGKAKIWDI 307 F P ++ FA+ + D +++D+ Sbjct: 232 CFFPNGNA-----FATGSDDATCRLFDL 254 Score = 38.1 bits (87), Expect = 0.023 Identities = 26/90 (28%), Positives = 41/90 (45%) Frame = +2 Query: 185 RTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDL 364 RT H AK+ A+ + + SA+ DGK IWD + + +S+ ++ Sbjct: 48 RTLRGHLAKIYAMHWGTDS-----RLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTC 102 Query: 365 DYFLPGGNEQYIITGSLSGNARIWNLRTHK 454 Y P GN Y+ G L I+NL+T + Sbjct: 103 AY-APSGN--YVACGGLDNICSIYNLKTRE 129
>GBB1_PONPY (Q5R5W8) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 339 Score = 48.1 bits (113), Expect = 2e-05 Identities = 25/88 (28%), Positives = 47/88 (53%) Frame = +2 Query: 44 EEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEAL 223 ++ F H G + +L++ P L +SG C+ KLWD +G C +TF H++ + A+ Sbjct: 174 QQTTTFTGHTGDVMSLSLAPDTRLFVSGACDAS-AKLWDVREG-MCRQTFTGHESDINAI 231 Query: 224 QFNPQNDSVGRTTFASAALDGKAKIWDI 307 F P ++ FA+ + D +++D+ Sbjct: 232 CFFPNGNA-----FATGSDDATCRLFDL 254 Score = 38.1 bits (87), Expect = 0.023 Identities = 26/90 (28%), Positives = 41/90 (45%) Frame = +2 Query: 185 RTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDL 364 RT H AK+ A+ + + SA+ DGK IWD + + +S+ ++ Sbjct: 48 RTLRGHLAKIYAMHWGTDS-----RLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTC 102 Query: 365 DYFLPGGNEQYIITGSLSGNARIWNLRTHK 454 Y P GN Y+ G L I+NL+T + Sbjct: 103 AY-APSGN--YVACGGLDNICSIYNLKTRE 129
>GBB1_MOUSE (P62874) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 339 Score = 48.1 bits (113), Expect = 2e-05 Identities = 25/88 (28%), Positives = 47/88 (53%) Frame = +2 Query: 44 EEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEAL 223 ++ F H G + +L++ P L +SG C+ KLWD +G C +TF H++ + A+ Sbjct: 174 QQTTTFTGHTGDVMSLSLAPDTRLFVSGACDAS-AKLWDVREG-MCRQTFTGHESDINAI 231 Query: 224 QFNPQNDSVGRTTFASAALDGKAKIWDI 307 F P ++ FA+ + D +++D+ Sbjct: 232 CFFPNGNA-----FATGSDDATCRLFDL 254 Score = 38.1 bits (87), Expect = 0.023 Identities = 26/90 (28%), Positives = 41/90 (45%) Frame = +2 Query: 185 RTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDL 364 RT H AK+ A+ + + SA+ DGK IWD + + +S+ ++ Sbjct: 48 RTLRGHLAKIYAMHWGTDS-----RLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTC 102 Query: 365 DYFLPGGNEQYIITGSLSGNARIWNLRTHK 454 Y P GN Y+ G L I+NL+T + Sbjct: 103 AY-APSGN--YVACGGLDNICSIYNLKTRE 129
>GBB1_HUMAN (P62873) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 339 Score = 48.1 bits (113), Expect = 2e-05 Identities = 25/88 (28%), Positives = 47/88 (53%) Frame = +2 Query: 44 EEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEAL 223 ++ F H G + +L++ P L +SG C+ KLWD +G C +TF H++ + A+ Sbjct: 174 QQTTTFTGHTGDVMSLSLAPDTRLFVSGACDAS-AKLWDVREG-MCRQTFTGHESDINAI 231 Query: 224 QFNPQNDSVGRTTFASAALDGKAKIWDI 307 F P ++ FA+ + D +++D+ Sbjct: 232 CFFPNGNA-----FATGSDDATCRLFDL 254 Score = 38.1 bits (87), Expect = 0.023 Identities = 26/90 (28%), Positives = 41/90 (45%) Frame = +2 Query: 185 RTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDL 364 RT H AK+ A+ + + SA+ DGK IWD + + +S+ ++ Sbjct: 48 RTLRGHLAKIYAMHWGTDS-----RLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTC 102 Query: 365 DYFLPGGNEQYIITGSLSGNARIWNLRTHK 454 Y P GN Y+ G L I+NL+T + Sbjct: 103 AY-APSGN--YVACGGLDNICSIYNLKTRE 129
>GBB1_CRIGR (Q6TMK6) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 339 Score = 48.1 bits (113), Expect = 2e-05 Identities = 25/88 (28%), Positives = 47/88 (53%) Frame = +2 Query: 44 EEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEAL 223 ++ F H G + +L++ P L +SG C+ KLWD +G C +TF H++ + A+ Sbjct: 174 QQTTTFTGHTGDVMSLSLAPDTRLFVSGACDAS-AKLWDVREG-MCRQTFTGHESDINAI 231 Query: 224 QFNPQNDSVGRTTFASAALDGKAKIWDI 307 F P ++ FA+ + D +++D+ Sbjct: 232 CFFPNGNA-----FATGSDDATCRLFDL 254 Score = 38.1 bits (87), Expect = 0.023 Identities = 26/90 (28%), Positives = 41/90 (45%) Frame = +2 Query: 185 RTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDL 364 RT H AK+ A+ + + SA+ DGK IWD + + +S+ ++ Sbjct: 48 RTLRGHLAKIYAMHWGTDS-----RLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTC 102 Query: 365 DYFLPGGNEQYIITGSLSGNARIWNLRTHK 454 Y P GN Y+ G L I+NL+T + Sbjct: 103 AY-APSGN--YVACGGLDNICSIYNLKTRE 129
>GBB1_CANFA (P62872) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 339 Score = 48.1 bits (113), Expect = 2e-05 Identities = 25/88 (28%), Positives = 47/88 (53%) Frame = +2 Query: 44 EEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEAL 223 ++ F H G + +L++ P L +SG C+ KLWD +G C +TF H++ + A+ Sbjct: 174 QQTTTFTGHTGDVMSLSLAPDTRLFVSGACDAS-AKLWDVREG-MCRQTFTGHESDINAI 231 Query: 224 QFNPQNDSVGRTTFASAALDGKAKIWDI 307 F P ++ FA+ + D +++D+ Sbjct: 232 CFFPNGNA-----FATGSDDATCRLFDL 254 Score = 38.1 bits (87), Expect = 0.023 Identities = 26/90 (28%), Positives = 41/90 (45%) Frame = +2 Query: 185 RTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDL 364 RT H AK+ A+ + + SA+ DGK IWD + + +S+ ++ Sbjct: 48 RTLRGHLAKIYAMHWGTDS-----RLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTC 102 Query: 365 DYFLPGGNEQYIITGSLSGNARIWNLRTHK 454 Y P GN Y+ G L I+NL+T + Sbjct: 103 AY-APSGN--YVACGGLDNICSIYNLKTRE 129
>GBB1_BOVIN (P62871) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 339 Score = 48.1 bits (113), Expect = 2e-05 Identities = 25/88 (28%), Positives = 47/88 (53%) Frame = +2 Query: 44 EEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEAL 223 ++ F H G + +L++ P L +SG C+ KLWD +G C +TF H++ + A+ Sbjct: 174 QQTTTFTGHTGDVMSLSLAPDTRLFVSGACDAS-AKLWDVREG-MCRQTFTGHESDINAI 231 Query: 224 QFNPQNDSVGRTTFASAALDGKAKIWDI 307 F P ++ FA+ + D +++D+ Sbjct: 232 CFFPNGNA-----FATGSDDATCRLFDL 254 Score = 38.1 bits (87), Expect = 0.023 Identities = 26/90 (28%), Positives = 41/90 (45%) Frame = +2 Query: 185 RTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDL 364 RT H AK+ A+ + + SA+ DGK IWD + + +S+ ++ Sbjct: 48 RTLRGHLAKIYAMHWGTDS-----RLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTC 102 Query: 365 DYFLPGGNEQYIITGSLSGNARIWNLRTHK 454 Y P GN Y+ G L I+NL+T + Sbjct: 103 AY-APSGN--YVACGGLDNICSIYNLKTRE 129
>RBBP7_BRARE (Q7ZTY4) Histone-binding protein RBBP7 (Retinoblastoma-binding| protein 7) (RBBP-7) Length = 426 Score = 48.1 bits (113), Expect = 2e-05 Identities = 32/120 (26%), Positives = 57/120 (47%) Frame = +2 Query: 65 AHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQND 244 AH + L+ +P +L+ G + LWD L +F +HK ++ +Q++P N+ Sbjct: 271 AHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNE 330 Query: 245 SVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGN 424 T AS+ D + +WD+S I + + +G +L F+ GG+ I S + N Sbjct: 331 ----TILASSGTDRRLNVWDLSKIGEEQSAEDAEDGPPEL-LFIHGGHTAKISDFSWNPN 385 Score = 34.3 bits (77), Expect = 0.34 Identities = 25/131 (19%), Positives = 54/131 (41%), Gaps = 3/131 (2%) Frame = +2 Query: 59 FKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCL--RTFNAHKAKVEALQFN 232 F H ++ ++ H L + + +WD T + +AH A+V L FN Sbjct: 223 FTGHTAVVEDVSWHLLHESLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFN 282 Query: 233 PQNDSVGRTTFASAALDGKAKIWDI-SLILPIATLDCQSNGLIDLDYFLPGGNEQYIITG 409 P ++ + A+ + D +WD+ +L L + + + + + + + NE + + Sbjct: 283 PYSEFI----LATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQW--SPHNETILASS 336 Query: 410 SLSGNARIWNL 442 +W+L Sbjct: 337 GTDRRLNVWDL 347
>YZLL_CAEEL (Q93847) Hypothetical WD-repeat protein K04G11.4| Length = 395 Score = 48.1 bits (113), Expect = 2e-05 Identities = 44/189 (23%), Positives = 82/189 (43%) Frame = +2 Query: 50 VKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQF 229 VK K H ++ +PS L+ SG ++ I++W G T + + H+ V ++ F Sbjct: 183 VKTLKGHTNYVFCCCFNPSGTLIASGSFDE-TIRIWCARNGNT-IFSIPGHEDPVSSVCF 240 Query: 230 NPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITG 409 N AS + DG +IWD + + TL + + I F P G +YI+ Sbjct: 241 NRDG-----AYLASGSYDGIVRIWDSTTGTCVKTLIDEEHPPITHVKFSPNG--KYILAS 293 Query: 410 SLSGNARIWNLRTHKCIRVIKGTSITSGAGCSVRVVYCSPDPPLLIRTFEDDSLGLCNST 589 +L+ ++W+ ++ +RV+K + + V + ++ ED + + N Sbjct: 294 NLNNTLKLWD---YQKLRVLKEYTGHENSKYCVAANFSVTGGKWIVSGSEDHKVYIWNLQ 350 Query: 590 TFRYTNTID 616 T T+D Sbjct: 351 TREILQTLD 359 Score = 43.5 bits (101), Expect = 6e-04 Identities = 30/122 (24%), Positives = 60/122 (49%), Gaps = 3/122 (2%) Frame = +2 Query: 119 LSGGCNQGLIKLWDWEKGWTCLRT-FNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAK 295 L+ G G++++WD G TC++T + + ++F+P G+ AS L+ K Sbjct: 247 LASGSYDGIVRIWDSTTG-TCVKTLIDEEHPPITHVKFSPN----GKYILAS-NLNNTLK 300 Query: 296 IWDISLILPIATLDCQSNG--LIDLDYFLPGGNEQYIITGSLSGNARIWNLRTHKCIRVI 469 +WD + + N + ++ + GG ++I++GS IWNL+T + ++ + Sbjct: 301 LWDYQKLRVLKEYTGHENSKYCVAANFSVTGG--KWIVSGSEDHKVYIWNLQTREILQTL 358 Query: 470 KG 475 G Sbjct: 359 DG 360 Score = 40.0 bits (92), Expect = 0.006 Identities = 31/120 (25%), Positives = 48/120 (40%), Gaps = 11/120 (9%) Frame = +2 Query: 143 LIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILP 322 L+K++D G C++T H V FNP T AS + D +IW Sbjct: 171 LVKVFDVSSG-RCVKTLKGHTNYVFCCCFNPSG-----TLIASGSFDETIRIW------- 217 Query: 323 IATLDCQSNGLIDLDYFLPGGNEQ-----------YIITGSLSGNARIWNLRTHKCIRVI 469 C NG + + +PG + Y+ +GS G RIW+ T C++ + Sbjct: 218 -----CARNG--NTIFSIPGHEDPVSSVCFNRDGAYLASGSYDGIVRIWDSTTGTCVKTL 270 Score = 32.7 bits (73), Expect = 0.98 Identities = 18/94 (19%), Positives = 45/94 (47%) Frame = +2 Query: 194 NAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYF 373 NAHK + ++F+P +G S + D KIW + + + + + ++ F Sbjct: 104 NAHKKSISGIKFSPDGRYMG-----SGSADCSIKIWRMDFVYEKTLMGHR----LGINEF 154 Query: 374 LPGGNEQYIITGSLSGNARIWNLRTHKCIRVIKG 475 + + I++ S +++++ + +C++ +KG Sbjct: 155 SWSSDSKLIVSCSDDKLVKVFDVSSGRCVKTLKG 188
>COPA_YEAST (P53622) Coatomer subunit alpha (Alpha-coat protein) (Alpha-COP)| Length = 1201 Score = 48.1 bits (113), Expect = 2e-05 Identities = 42/146 (28%), Positives = 65/146 (44%), Gaps = 1/146 (0%) Frame = +2 Query: 41 LEEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEA 220 ++ + KF++ + + +A HPS P +L I+LWD+ G T L F H+ V Sbjct: 1 MKMLTKFESKSTRAKGIAFHPSRPWVLV-ALFSSTIQLWDYRMG-TLLHRFEDHEGPVRG 58 Query: 221 LQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNE-QY 397 L F+P + F SA D K+W + + TL G +D + E + Sbjct: 59 LDFHPT-----QPIFVSAGDDYTIKVWSLDTNKCLYTL----TGHLDYVRTVFFHRELPW 109 Query: 398 IITGSLSGNARIWNLRTHKCIRVIKG 475 II+ S RIWN + K I + G Sbjct: 110 IISASDDQTIRIWNWQNRKEIACLTG 135 Score = 42.0 bits (97), Expect = 0.002 Identities = 38/142 (26%), Positives = 62/142 (43%) Frame = +2 Query: 56 KFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNP 235 +F+ H G ++ L HP+ P+ +S G + IK+W + CL T H V + F+ Sbjct: 48 RFEDHEGPVRGLDFHPTQPIFVSAG-DDYTIKVWSLDTN-KCLYTLTGHLDYVRTVFFHR 105 Query: 236 QNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSL 415 + + SA+ D +IW+ IA L N + F P + I++ SL Sbjct: 106 ELPWI-----ISASDDQTIRIWNWQNRKEIACL-TGHNHFVMCAQFHP--TDDLIVSASL 157 Query: 416 SGNARIWNLRTHKCIRVIKGTS 481 RIW++ + GTS Sbjct: 158 DETIRIWDISGLRKRHSAPGTS 179 Score = 37.4 bits (85), Expect = 0.040 Identities = 23/90 (25%), Positives = 42/90 (46%), Gaps = 2/90 (2%) Frame = +2 Query: 62 KAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWE--KGWTCLRTFNAHKAKVEALQFNP 235 + H + + HP+LPL++SG + +KLW K W + T H V+++ F+P Sbjct: 206 EGHTRGVNWASFHPTLPLIVSGS-DDRQVKLWRMSATKAWE-VDTCRGHTNNVDSVIFHP 263 Query: 236 QNDSVGRTTFASAALDGKAKIWDISLILPI 325 + + S D ++WD+ P+ Sbjct: 264 HQNLI-----ISVGEDKTLRVWDLDKRTPV 288
>RBBP7_RAT (Q71UF4) Histone-binding protein RBBP7 (Retinoblastoma-binding| protein 7) (RBBP-7) Length = 425 Score = 47.8 bits (112), Expect = 3e-05 Identities = 32/120 (26%), Positives = 56/120 (46%) Frame = +2 Query: 65 AHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQND 244 AH + L+ +P +L+ G + LWD L TF +HK ++ + ++P N+ Sbjct: 270 AHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHTFESHKDEIFQVHWSPHNE 329 Query: 245 SVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGN 424 T AS+ D + +WD+S I + + +G +L F+ GG+ I S + N Sbjct: 330 ----TILASSGTDRRLNVWDLSKIGEEQSAEDAEDGPPEL-LFIHGGHTAKISDFSWNPN 384 Score = 37.0 bits (84), Expect = 0.052 Identities = 27/131 (20%), Positives = 55/131 (41%), Gaps = 3/131 (2%) Frame = +2 Query: 59 FKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTF--NAHKAKVEALQFN 232 F H+ ++ +A H L + + +WD T + +AH A+V L FN Sbjct: 222 FTGHSAVVEDVAWHLLHESLFGSVADDQKLMIWDTRSNTTSKPSHLVDAHTAEVNCLSFN 281 Query: 233 PQNDSVGRTTFASAALDGKAKIWDI-SLILPIATLDCQSNGLIDLDYFLPGGNEQYIITG 409 P ++ + A+ + D +WD+ +L L + T + + + + + NE + + Sbjct: 282 PYSEFI----LATGSADKTVALWDLRNLKLKLHTFESHKDEIFQVHW--SPHNETILASS 335 Query: 410 SLSGNARIWNL 442 +W+L Sbjct: 336 GTDRRLNVWDL 346
>RBBP7_MOUSE (Q60973) Histone-binding protein RBBP7 (Retinoblastoma-binding| protein 7) (RBBP-7) (Retinoblastoma-binding protein p46) (Histone acetyltransferase type B subunit 2) Length = 425 Score = 47.8 bits (112), Expect = 3e-05 Identities = 32/120 (26%), Positives = 56/120 (46%) Frame = +2 Query: 65 AHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQND 244 AH + L+ +P +L+ G + LWD L TF +HK ++ + ++P N+ Sbjct: 270 AHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHTFESHKDEIFQVHWSPHNE 329 Query: 245 SVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGN 424 T AS+ D + +WD+S I + + +G +L F+ GG+ I S + N Sbjct: 330 ----TILASSGTDRRLNVWDLSKIGEEQSAEDAEDGPPEL-LFIHGGHTAKISDFSWNPN 384 Score = 37.0 bits (84), Expect = 0.052 Identities = 27/131 (20%), Positives = 55/131 (41%), Gaps = 3/131 (2%) Frame = +2 Query: 59 FKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTF--NAHKAKVEALQFN 232 F H+ ++ +A H L + + +WD T + +AH A+V L FN Sbjct: 222 FTGHSAVVEDVAWHLLHESLFGSVADDQKLMIWDTRSNTTSKPSHLVDAHTAEVNCLSFN 281 Query: 233 PQNDSVGRTTFASAALDGKAKIWDI-SLILPIATLDCQSNGLIDLDYFLPGGNEQYIITG 409 P ++ + A+ + D +WD+ +L L + T + + + + + NE + + Sbjct: 282 PYSEFI----LATGSADKTVALWDLRNLKLKLHTFESHKDEIFQVHW--SPHNETILASS 335 Query: 410 SLSGNARIWNL 442 +W+L Sbjct: 336 GTDRRLNVWDL 346
>RBBP7_MACFA (Q4R304) Histone-binding protein RBBP7 (Retinoblastoma-binding| protein 7) (RBBP-7) Length = 425 Score = 47.8 bits (112), Expect = 3e-05 Identities = 32/120 (26%), Positives = 56/120 (46%) Frame = +2 Query: 65 AHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQND 244 AH + L+ +P +L+ G + LWD L TF +HK ++ + ++P N+ Sbjct: 270 AHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHTFESHKDEIFQVHWSPHNE 329 Query: 245 SVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGN 424 T AS+ D + +WD+S I + + +G +L F+ GG+ I S + N Sbjct: 330 ----TILASSGTDRRLNVWDLSKIGEEQSAEDAEDGPPEL-LFIHGGHTAKISDFSWNPN 384 Score = 37.0 bits (84), Expect = 0.052 Identities = 27/131 (20%), Positives = 55/131 (41%), Gaps = 3/131 (2%) Frame = +2 Query: 59 FKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTF--NAHKAKVEALQFN 232 F H+ ++ +A H L + + +WD T + +AH A+V L FN Sbjct: 222 FTGHSAVVEDVAWHLLHESLFGSVADDQKLMIWDTRSNTTSKPSHLVDAHTAEVNCLSFN 281 Query: 233 PQNDSVGRTTFASAALDGKAKIWDI-SLILPIATLDCQSNGLIDLDYFLPGGNEQYIITG 409 P ++ + A+ + D +WD+ +L L + T + + + + + NE + + Sbjct: 282 PYSEFI----LATGSADKTVALWDLRNLKLKLHTFESHKDEIFQVHW--SPHNETILASS 335 Query: 410 SLSGNARIWNL 442 +W+L Sbjct: 336 GTDRRLNVWDL 346
>RBBP7_HUMAN (Q16576) Histone-binding protein RBBP7 (Retinoblastoma-binding| protein 7) (RBBP-7) (Retinoblastoma-binding protein p46) (Histone acetyltransferase type B subunit 2) Length = 425 Score = 47.8 bits (112), Expect = 3e-05 Identities = 32/120 (26%), Positives = 56/120 (46%) Frame = +2 Query: 65 AHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQND 244 AH + L+ +P +L+ G + LWD L TF +HK ++ + ++P N+ Sbjct: 270 AHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHTFESHKDEIFQVHWSPHNE 329 Query: 245 SVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGN 424 T AS+ D + +WD+S I + + +G +L F+ GG+ I S + N Sbjct: 330 ----TILASSGTDRRLNVWDLSKIGEEQSAEDAEDGPPEL-LFIHGGHTAKISDFSWNPN 384 Score = 37.0 bits (84), Expect = 0.052 Identities = 27/131 (20%), Positives = 55/131 (41%), Gaps = 3/131 (2%) Frame = +2 Query: 59 FKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTF--NAHKAKVEALQFN 232 F H+ ++ +A H L + + +WD T + +AH A+V L FN Sbjct: 222 FTGHSAVVEDVAWHLLHESLFGSVADDQKLMIWDTRSNTTSKPSHLVDAHTAEVNCLSFN 281 Query: 233 PQNDSVGRTTFASAALDGKAKIWDI-SLILPIATLDCQSNGLIDLDYFLPGGNEQYIITG 409 P ++ + A+ + D +WD+ +L L + T + + + + + NE + + Sbjct: 282 PYSEFI----LATGSADKTVALWDLRNLKLKLHTFESHKDEIFQVHW--SPHNETILASS 335 Query: 410 SLSGNARIWNL 442 +W+L Sbjct: 336 GTDRRLNVWDL 346
>RBBP7_BOVIN (Q3SWX8) Histone-binding protein RBBP7 (Retinoblastoma-binding| protein 7) (RBBP-7) Length = 425 Score = 47.8 bits (112), Expect = 3e-05 Identities = 32/120 (26%), Positives = 56/120 (46%) Frame = +2 Query: 65 AHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQND 244 AH + L+ +P +L+ G + LWD L TF +HK ++ + ++P N+ Sbjct: 270 AHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHTFESHKDEIFQVHWSPHNE 329 Query: 245 SVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGN 424 T AS+ D + +WD+S I + + +G +L F+ GG+ I S + N Sbjct: 330 ----TILASSGTDRRLNVWDLSKIGEEQSAEDAEDGPPEL-LFIHGGHTAKISDFSWNPN 384 Score = 37.0 bits (84), Expect = 0.052 Identities = 27/131 (20%), Positives = 55/131 (41%), Gaps = 3/131 (2%) Frame = +2 Query: 59 FKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTF--NAHKAKVEALQFN 232 F H+ ++ +A H L + + +WD T + +AH A+V L FN Sbjct: 222 FTGHSAVVEDVAWHLLHESLFGSVADDQKLMIWDTRSNTTSKPSHLVDAHTAEVNCLSFN 281 Query: 233 PQNDSVGRTTFASAALDGKAKIWDI-SLILPIATLDCQSNGLIDLDYFLPGGNEQYIITG 409 P ++ + A+ + D +WD+ +L L + T + + + + + NE + + Sbjct: 282 PYSEFI----LATGSADKTVALWDLRNLKLKLHTFESHKDEIFQVHW--SPHNETILASS 335 Query: 410 SLSGNARIWNL 442 +W+L Sbjct: 336 GTDRRLNVWDL 346
>MET30_YEAST (P39014) F-box protein MET30 (Methionine requiring protein 30) (E3| ubiquitin ligase complex SCF(Met30) subunit MET30) Length = 640 Score = 47.8 bits (112), Expect = 3e-05 Identities = 34/108 (31%), Positives = 50/108 (46%) Frame = +2 Query: 158 DWEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLD 337 +W KG ++ F H V LQFN + + + D IWD+ I L Sbjct: 287 NWRKGHCRIQEFKGHMDGVLTLQFNYR-------LLFTGSYDSTIGIWDLFTGKLIRRLS 339 Query: 338 CQSNGLIDLDYFLPGGNEQYIITGSLSGNARIWNLRTHKCIRVIKGTS 481 S+G+ L YF +++ +ITGSL R+WN T +CI +G S Sbjct: 340 GHSDGVKTL-YF----DDRKLITGSLDKTIRVWNYITGECISTYRGHS 382 Score = 40.4 bits (93), Expect = 0.005 Identities = 37/180 (20%), Positives = 64/180 (35%), Gaps = 42/180 (23%) Frame = +2 Query: 62 KAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEAL------ 223 + H W+ + +HP S + I++WD +CL+ F H +V+ + Sbjct: 418 RGHTEWVNCVKLHPKSFSCFSCS-DDTTIRMWDIRTN-SCLKVFRGHVGQVQKIIPLTIK 475 Query: 224 ------------QFNPQNDSVGR------------------------TTFASAALDGKAK 295 +PQ+D T S LD K Sbjct: 476 DVENLATDNTSDGSSPQDDPTMTDGADESDTPSNEQETVLDENIPYPTHLLSCGLDNTIK 535 Query: 296 IWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNARIWNLRTHKCIRVIKG 475 +WD+ I T G+ D+ + II+GS G+ ++W+L++ KC+ G Sbjct: 536 LWDVKTGKCIRTQFGHVEGVWDI-----AADNFRIISGSHDGSIKVWDLQSGKCMHTFNG 590
>CAF1_DROME (Q24572) Probable histone-binding protein Caf1 (Chromatin assembly| factor 1 p55 subunit) (CAF-1 p55 subunit) (dCAF-1) (Nucleosome remodeling factor 55 kDa subunit) (NURF-55) Length = 430 Score = 47.8 bits (112), Expect = 3e-05 Identities = 32/120 (26%), Positives = 57/120 (47%) Frame = +2 Query: 65 AHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQND 244 AH + L+ +P +L+ G + LWD L +F +HK ++ +Q++P N+ Sbjct: 275 AHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNE 334 Query: 245 SVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGN 424 T AS+ D + +WD+S I + + +G +L F+ GG+ I S + N Sbjct: 335 ----TILASSGTDRRLHVWDLSKIGEEQSTEDAEDGPPEL-LFIHGGHTAKISDFSWNPN 389 Score = 37.0 bits (84), Expect = 0.052 Identities = 27/131 (20%), Positives = 54/131 (41%), Gaps = 3/131 (2%) Frame = +2 Query: 59 FKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCL--RTFNAHKAKVEALQFN 232 F H ++ +A H L + + +WD T T +AH A+V L FN Sbjct: 227 FTGHTAVVEDVAWHLLHESLFGSVADDQKLMIWDTRNNNTSKPSHTVDAHTAEVNCLSFN 286 Query: 233 PQNDSVGRTTFASAALDGKAKIWDI-SLILPIATLDCQSNGLIDLDYFLPGGNEQYIITG 409 P ++ + A+ + D +WD+ +L L + + + + + + + NE + + Sbjct: 287 PYSEFI----LATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQW--SPHNETILASS 340 Query: 410 SLSGNARIWNL 442 +W+L Sbjct: 341 GTDRRLHVWDL 351
>MEP50_HUMAN (Q9BQA1) Methylosome protein 50 (MEP50 protein) (WD-repeat protein| 77) Length = 342 Score = 47.8 bits (112), Expect = 3e-05 Identities = 42/187 (22%), Positives = 80/187 (42%) Frame = +2 Query: 29 KTLGLEEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKA 208 +TL + + K++ H+ + ++V S +SG IK+WD + L ++ AH A Sbjct: 112 ETLIVSKFCKYE-HDDIVSTVSVLSSGTQAVSGS-KDICIKVWDLAQQ-VVLSSYRAHAA 168 Query: 209 KVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGN 388 +V + +P DSV F S + D + +WD P + + C + G + Sbjct: 169 QVTCVAASPHKDSV----FLSCSEDNRILLWDTRCPKPASQIGCSAPGYLPTSLAWHPQQ 224 Query: 389 EQYIITGSLSGNARIWNLRTHKCIRVIKGTSITSGAGCSVRVVYCSPDPPLLIRTFEDDS 568 + + G +G + + ++ C+ S + C +V+ P L ED S Sbjct: 225 SEVFVFGDENGTVSLVDTKSTSCV-----LSSAVHSQCVTGLVFSPHSVPFLASLSEDCS 279 Query: 569 LGLCNST 589 L + +S+ Sbjct: 280 LAVLDSS 286
>TUP1_CANAL (P56093) Transcriptional repressor TUP1| Length = 514 Score = 47.8 bits (112), Expect = 3e-05 Identities = 37/119 (31%), Positives = 56/119 (47%) Frame = +2 Query: 266 ASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNARIWNLR 445 A+ A D +IWD+S I L + LD+F P G+ +++GS + RIW+LR Sbjct: 273 ATGAEDKLIRIWDLSTKRIIKILRGHEQDIYSLDFF-PDGDR--LVSGSGDRSVRIWDLR 329 Query: 446 THKCIRVIKGTSITSGAGCSVRVVYCSPDPPLLIRTFEDDSLGLCNSTTFRYTNTIDFG 622 T +C S+T V V SPD L+ D ++ + +STT +D G Sbjct: 330 TSQC-------SLTLSIEDGVTTVAVSPDGKLIAAGSLDRTVRVWDSTTGFLVERLDSG 381 Score = 34.3 bits (77), Expect = 0.34 Identities = 32/135 (23%), Positives = 57/135 (42%), Gaps = 4/135 (2%) Frame = +2 Query: 50 VKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQF 229 +K + H I +L P L+SG ++ +++WD C T + V + Sbjct: 292 IKILRGHEQDIYSLDFFPDGDRLVSGSGDRS-VRIWDLRTS-QCSLTLSIEDG-VTTVAV 348 Query: 230 NPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDC---QSNGLIDLDYFLP-GGNEQY 397 +P + A+ +LD ++WD + + LD NG D Y + N + Sbjct: 349 SPDGKLI-----AAGSLDRTVRVWDSTTGFLVERLDSGNENGNGHEDSVYSVAFSNNGEQ 403 Query: 398 IITGSLSGNARIWNL 442 I +GSL ++W+L Sbjct: 404 IASGSLDRTVKLWHL 418
>KTNB1_MOUSE (Q8BG40) Katanin p80 WD40-containing subunit B1 (Katanin p80| subunit B1) (p80 katanin) Length = 658 Score = 47.4 bits (111), Expect = 4e-05 Identities = 43/161 (26%), Positives = 69/161 (42%), Gaps = 3/161 (1%) Frame = +2 Query: 2 VMGXPPAXCKTLGLEEVKKFKA---HNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKG 172 V G + LE K + H I +L HP + SG + IKLWD + Sbjct: 79 VAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTN-IKLWDIRRK 137 Query: 173 WTCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNG 352 C+ + H V L+F+P + ASAA D K+WD++ ++ + G Sbjct: 138 G-CVFRYRGHSQAVRCLRFSPDGKWL-----ASAADDHTVKLWDLTAGKMMSEFPGHT-G 190 Query: 353 LIDLDYFLPGGNEQYIITGSLSGNARIWNLRTHKCIRVIKG 475 +++ F P NE + +GS R W+L + + I+G Sbjct: 191 PVNVVEFHP--NEYLLASGSSDRTIRFWDLEKFQVVSCIEG 229 Score = 42.0 bits (97), Expect = 0.002 Identities = 24/64 (37%), Positives = 33/64 (51%) Frame = +2 Query: 116 LLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAK 295 L+ G G I++WD E LRT HKA + +L F+P + V AS + D K Sbjct: 77 LIVAGSQSGSIRVWDLEAA-KILRTLMGHKANICSLDFHPYGEFV-----ASGSQDTNIK 130 Query: 296 IWDI 307 +WDI Sbjct: 131 LWDI 134 Score = 32.3 bits (72), Expect = 1.3 Identities = 18/62 (29%), Positives = 30/62 (48%) Frame = +2 Query: 50 VKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQF 229 + +F H G + + HP+ LL SG ++ I+ WD EK + + V ++ F Sbjct: 182 MSEFPGHTGPVNVVEFHPNEYLLASGSSDR-TIRFWDLEK-FQVVSCIEGEPGPVRSVLF 239 Query: 230 NP 235 NP Sbjct: 240 NP 241
>RBBP4_BRARE (Q6P3H7) Histone-binding protein RBBP4 (Retinoblastoma-binding| protein 4) (RBBP-4) Length = 423 Score = 47.4 bits (111), Expect = 4e-05 Identities = 32/120 (26%), Positives = 57/120 (47%) Frame = +2 Query: 65 AHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQND 244 AH + L+ +P +L+ G + LWD L +F +HK ++ +Q++P N+ Sbjct: 270 AHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNE 329 Query: 245 SVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGN 424 T AS+ D + +WD+S I + + +G +L F+ GG+ I S + N Sbjct: 330 ----TILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPEL-LFIHGGHTAKISDFSWNPN 384 Score = 33.9 bits (76), Expect = 0.44 Identities = 25/131 (19%), Positives = 53/131 (40%), Gaps = 3/131 (2%) Frame = +2 Query: 59 FKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCL--RTFNAHKAKVEALQFN 232 F H ++ ++ H L + + +WD T +AH A+V L FN Sbjct: 222 FTGHTAVVEDVSWHLLHESLFGSVADDQKLMIWDTRSNNTSKPSHAVDAHTAEVNCLSFN 281 Query: 233 PQNDSVGRTTFASAALDGKAKIWDI-SLILPIATLDCQSNGLIDLDYFLPGGNEQYIITG 409 P ++ + A+ + D +WD+ +L L + + + + + + + NE + + Sbjct: 282 PYSEFI----LATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQW--SPHNETILASS 335 Query: 410 SLSGNARIWNL 442 +W+L Sbjct: 336 GTDRRLNVWDL 346
>SCONB_EMENI (Q00659) Sulfur metabolite repression control protein| Length = 678 Score = 47.4 bits (111), Expect = 4e-05 Identities = 30/106 (28%), Positives = 50/106 (47%) Frame = +2 Query: 158 DWEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLD 337 +W+ G ++TF H V LQF D++ A+ + D KIWD + TL Sbjct: 334 NWKYGRCSIKTFKGHTNGVMCLQFE---DNI----LATGSYDTTIKIWDTETGEELRTLR 386 Query: 338 CQSNGLIDLDYFLPGGNEQYIITGSLSGNARIWNLRTHKCIRVIKG 475 +G+ L + ++ +I+GS+ ++WN RT +CI G Sbjct: 387 GHESGIRCLQF-----DDTKLISGSMDRTIKVWNWRTGECISTYTG 427 Score = 45.8 bits (107), Expect = 1e-04 Identities = 38/147 (25%), Positives = 63/147 (42%), Gaps = 3/147 (2%) Frame = +2 Query: 44 EEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEAL 223 EE++ + H I+ L + L+SG ++ IK+W+W G C+ T+ H+ V L Sbjct: 380 EELRTLRGHESGIRCLQFDDTK--LISGSMDR-TIKVWNWRTG-ECISTYTGHRGGVIGL 435 Query: 224 QFNPQNDSVGRTTFASAALDGKAKIW---DISLILPIATLDCQSNGLIDLDYFLPGGNEQ 394 F+ + AS ++D KIW D S D + +D + + Sbjct: 436 HFDA-------SILASGSVDKTVKIWNFEDKSTFSLRGHTDWVNAVRVDT-------SSR 481 Query: 395 YIITGSLSGNARIWNLRTHKCIRVIKG 475 + + S R+W+L T CIR G Sbjct: 482 TVFSASDDCTVRLWDLDTKTCIRTFHG 508 Score = 41.6 bits (96), Expect = 0.002 Identities = 31/145 (21%), Positives = 58/145 (40%), Gaps = 7/145 (4%) Frame = +2 Query: 62 KAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEAL------ 223 + H W+ A+ V S + S + ++LWD + TC+RTF+ H +V+ + Sbjct: 465 RGHTDWVNAVRVDTSSRTVFSAS-DDCTVRLWDLDTK-TCIRTFHGHVGQVQQVVPLPRE 522 Query: 224 -QFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYI 400 +F + ++ + D S+ L QS+ +Y+ Sbjct: 523 FEFEEHDAECENDDLSTTSGDANPPSIQASMGLEPNAAYSQSSAFGTSFDNGRAAPPRYM 582 Query: 401 ITGSLSGNARIWNLRTHKCIRVIKG 475 +T +L R+W T +C+R G Sbjct: 583 VTSALDSTIRLWETTTGRCLRTFFG 607
>PRP4_HUMAN (O43172) U4/U6 small nuclear ribonucleoprotein Prp4 (U4/U6 snRNP 60| kDa protein) (WD splicing factor Prp4) (hPrp4) Length = 522 Score = 47.4 bits (111), Expect = 4e-05 Identities = 35/145 (24%), Positives = 60/145 (41%), Gaps = 7/145 (4%) Frame = +2 Query: 62 KAHNGWIQALAVHPSLPLLLS------GGCN-QGLIKLWDWEKGWTCLRTFNAHKAKVEA 220 + HN + A+ HP + L C G +KLW + + H +V Sbjct: 270 RGHNTNVGAIVFHPKSTVSLDPKDVNLASCAADGSVKLWSLDSDEP-VADIEGHTVRVAR 328 Query: 221 LQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYI 400 + ++P +G T + D ++WD+ I + S G+ D+ + G Sbjct: 329 VMWHPSGRFLGTTCY-----DRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAG-- 381 Query: 401 ITGSLSGNARIWNLRTHKCIRVIKG 475 TG L R+W+LRT +CI ++G Sbjct: 382 -TGGLDAFGRVWDLRTGRCIMFLEG 405 Score = 39.7 bits (91), Expect = 0.008 Identities = 35/142 (24%), Positives = 55/142 (38%) Frame = +2 Query: 44 EEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEAL 223 E V + H + + HPS L C +LWD E L H V + Sbjct: 314 EPVADIEGHTVRVARVMWHPS-GRFLGTTCYDRSWRLWDLEAQEEILHQ-EGHSMGVYDI 371 Query: 224 QFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYII 403 F+ G + LD ++WD+ I L+ + ++ F P G +I Sbjct: 372 AFHQDGSLAG-----TGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGIN-FSPNG--YHIA 423 Query: 404 TGSLSGNARIWNLRTHKCIRVI 469 TGS ++W+LR +C+ I Sbjct: 424 TGSGDNTCKVWDLRQRRCVYTI 445
>RBP4B_XENLA (Q6INH0) Histone-binding protein RBBP4-B (Retinoblastoma-binding| protein 4-B) (RBBP-4-B) (Retinoblastoma-binding protein p48-B) Length = 424 Score = 47.4 bits (111), Expect = 4e-05 Identities = 32/120 (26%), Positives = 57/120 (47%) Frame = +2 Query: 65 AHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQND 244 AH + L+ +P +L+ G + LWD L +F +HK ++ +Q++P N+ Sbjct: 270 AHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNE 329 Query: 245 SVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGN 424 T AS+ D + +WD+S I + + +G +L F+ GG+ I S + N Sbjct: 330 ----TILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPEL-LFIHGGHTAKISDFSWNPN 384 Score = 34.3 bits (77), Expect = 0.34 Identities = 25/131 (19%), Positives = 54/131 (41%), Gaps = 3/131 (2%) Frame = +2 Query: 59 FKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCL--RTFNAHKAKVEALQFN 232 F H ++ ++ H L + + +WD T + +AH A+V L FN Sbjct: 222 FTGHTAVVEDVSWHLLHESLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFN 281 Query: 233 PQNDSVGRTTFASAALDGKAKIWDI-SLILPIATLDCQSNGLIDLDYFLPGGNEQYIITG 409 P ++ + A+ + D +WD+ +L L + + + + + + + NE + + Sbjct: 282 PYSEFI----LATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQW--SPHNETILASS 335 Query: 410 SLSGNARIWNL 442 +W+L Sbjct: 336 GTDRRLNVWDL 346
>RBP4A_XENLA (O93377) Histone-binding protein RBBP4-A (Retinoblastoma-binding| protein 4-A) (RBBP-4-A) (Retinoblastoma-binding protein p48-A) Length = 424 Score = 47.4 bits (111), Expect = 4e-05 Identities = 32/120 (26%), Positives = 57/120 (47%) Frame = +2 Query: 65 AHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQND 244 AH + L+ +P +L+ G + LWD L +F +HK ++ +Q++P N+ Sbjct: 270 AHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNE 329 Query: 245 SVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGN 424 T AS+ D + +WD+S I + + +G +L F+ GG+ I S + N Sbjct: 330 ----TILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPEL-LFIHGGHTAKISDFSWNPN 384 Score = 34.3 bits (77), Expect = 0.34 Identities = 25/131 (19%), Positives = 54/131 (41%), Gaps = 3/131 (2%) Frame = +2 Query: 59 FKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCL--RTFNAHKAKVEALQFN 232 F H ++ ++ H L + + +WD T + +AH A+V L FN Sbjct: 222 FTGHTAVVEDVSWHLLHESLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFN 281 Query: 233 PQNDSVGRTTFASAALDGKAKIWDI-SLILPIATLDCQSNGLIDLDYFLPGGNEQYIITG 409 P ++ + A+ + D +WD+ +L L + + + + + + + NE + + Sbjct: 282 PYSEFI----LATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQW--SPHNETILASS 335 Query: 410 SLSGNARIWNL 442 +W+L Sbjct: 336 GTDRRLNVWDL 346
>RBBP4_XENTR (Q5M7K4) Histone-binding protein RBBP4 (Retinoblastoma-binding| protein 4) (RBBP-4) Length = 424 Score = 47.4 bits (111), Expect = 4e-05 Identities = 32/120 (26%), Positives = 57/120 (47%) Frame = +2 Query: 65 AHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQND 244 AH + L+ +P +L+ G + LWD L +F +HK ++ +Q++P N+ Sbjct: 270 AHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNE 329 Query: 245 SVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGN 424 T AS+ D + +WD+S I + + +G +L F+ GG+ I S + N Sbjct: 330 ----TILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPEL-LFIHGGHTAKISDFSWNPN 384 Score = 34.3 bits (77), Expect = 0.34 Identities = 25/131 (19%), Positives = 54/131 (41%), Gaps = 3/131 (2%) Frame = +2 Query: 59 FKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCL--RTFNAHKAKVEALQFN 232 F H ++ ++ H L + + +WD T + +AH A+V L FN Sbjct: 222 FTGHTAVVEDVSWHLLHESLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFN 281 Query: 233 PQNDSVGRTTFASAALDGKAKIWDI-SLILPIATLDCQSNGLIDLDYFLPGGNEQYIITG 409 P ++ + A+ + D +WD+ +L L + + + + + + + NE + + Sbjct: 282 PYSEFI----LATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQW--SPHNETILASS 335 Query: 410 SLSGNARIWNL 442 +W+L Sbjct: 336 GTDRRLNVWDL 346
>RBBP4_PONPY (Q5RF92) Histone-binding protein RBBP4 (Retinoblastoma-binding| protein 4) (RBBP-4) Length = 424 Score = 47.4 bits (111), Expect = 4e-05 Identities = 32/120 (26%), Positives = 57/120 (47%) Frame = +2 Query: 65 AHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQND 244 AH + L+ +P +L+ G + LWD L +F +HK ++ +Q++P N+ Sbjct: 270 AHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNE 329 Query: 245 SVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGN 424 T AS+ D + +WD+S I + + +G +L F+ GG+ I S + N Sbjct: 330 ----TILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPEL-LFIHGGHTAKISDFSWNPN 384 Score = 34.3 bits (77), Expect = 0.34 Identities = 25/131 (19%), Positives = 54/131 (41%), Gaps = 3/131 (2%) Frame = +2 Query: 59 FKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCL--RTFNAHKAKVEALQFN 232 F H ++ ++ H L + + +WD T + +AH A+V L FN Sbjct: 222 FTGHTAVVEDVSWHLLHESLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFN 281 Query: 233 PQNDSVGRTTFASAALDGKAKIWDI-SLILPIATLDCQSNGLIDLDYFLPGGNEQYIITG 409 P ++ + A+ + D +WD+ +L L + + + + + + + NE + + Sbjct: 282 PYSEFI----LATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQW--SPHNETILASS 335 Query: 410 SLSGNARIWNL 442 +W+L Sbjct: 336 GTDRRLNVWDL 346
>RBBP4_MOUSE (Q60972) Histone-binding protein RBBP4 (Retinoblastoma-binding| protein 4) (RBBP-4) (Retinoblastoma-binding protein p48) (Chromatin assembly factor 1 subunit C) (CAF-1 subunit C) (Chromatin assembly factor I p48 subunit) (CAF-I 48 kDa subunit) Length = 424 Score = 47.4 bits (111), Expect = 4e-05 Identities = 32/120 (26%), Positives = 57/120 (47%) Frame = +2 Query: 65 AHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQND 244 AH + L+ +P +L+ G + LWD L +F +HK ++ +Q++P N+ Sbjct: 270 AHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNE 329 Query: 245 SVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGN 424 T AS+ D + +WD+S I + + +G +L F+ GG+ I S + N Sbjct: 330 ----TILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPEL-LFIHGGHTAKISDFSWNPN 384 Score = 34.3 bits (77), Expect = 0.34 Identities = 25/131 (19%), Positives = 54/131 (41%), Gaps = 3/131 (2%) Frame = +2 Query: 59 FKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCL--RTFNAHKAKVEALQFN 232 F H ++ ++ H L + + +WD T + +AH A+V L FN Sbjct: 222 FTGHTAVVEDVSWHLLHESLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFN 281 Query: 233 PQNDSVGRTTFASAALDGKAKIWDI-SLILPIATLDCQSNGLIDLDYFLPGGNEQYIITG 409 P ++ + A+ + D +WD+ +L L + + + + + + + NE + + Sbjct: 282 PYSEFI----LATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQW--SPHNETILASS 335 Query: 410 SLSGNARIWNL 442 +W+L Sbjct: 336 GTDRRLNVWDL 346
>RBBP4_HUMAN (Q09028) Histone-binding protein RBBP4 (Retinoblastoma-binding| protein 4) (RBBP-4) (Retinoblastoma-binding protein p48) (Chromatin assembly factor 1 subunit C) (CAF-1 subunit C) (Chromatin assembly factor I p48 subunit) (CAF-I 48 kDa subunit) Length = 424 Score = 47.4 bits (111), Expect = 4e-05 Identities = 32/120 (26%), Positives = 57/120 (47%) Frame = +2 Query: 65 AHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQND 244 AH + L+ +P +L+ G + LWD L +F +HK ++ +Q++P N+ Sbjct: 270 AHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNE 329 Query: 245 SVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGN 424 T AS+ D + +WD+S I + + +G +L F+ GG+ I S + N Sbjct: 330 ----TILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPEL-LFIHGGHTAKISDFSWNPN 384 Score = 34.3 bits (77), Expect = 0.34 Identities = 25/131 (19%), Positives = 54/131 (41%), Gaps = 3/131 (2%) Frame = +2 Query: 59 FKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCL--RTFNAHKAKVEALQFN 232 F H ++ ++ H L + + +WD T + +AH A+V L FN Sbjct: 222 FTGHTAVVEDVSWHLLHESLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFN 281 Query: 233 PQNDSVGRTTFASAALDGKAKIWDI-SLILPIATLDCQSNGLIDLDYFLPGGNEQYIITG 409 P ++ + A+ + D +WD+ +L L + + + + + + + NE + + Sbjct: 282 PYSEFI----LATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQW--SPHNETILASS 335 Query: 410 SLSGNARIWNL 442 +W+L Sbjct: 336 GTDRRLNVWDL 346
>RBBP4_CHICK (Q9W7I5) Histone-binding protein RBBP4 (Retinoblastoma-binding| protein 4) (RBBP-4) (Retinoblastoma-binding protein p48) (Chromatin assembly factor 1 subunit C) (CAF-1 subunit C) (Chromatin assembly factor I p48 subunit) (CAF-I 48 kDa subunit) Length = 424 Score = 47.4 bits (111), Expect = 4e-05 Identities = 32/120 (26%), Positives = 57/120 (47%) Frame = +2 Query: 65 AHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQND 244 AH + L+ +P +L+ G + LWD L +F +HK ++ +Q++P N+ Sbjct: 270 AHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNE 329 Query: 245 SVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGN 424 T AS+ D + +WD+S I + + +G +L F+ GG+ I S + N Sbjct: 330 ----TILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPEL-LFIHGGHTAKISDFSWNPN 384 Score = 34.3 bits (77), Expect = 0.34 Identities = 25/131 (19%), Positives = 54/131 (41%), Gaps = 3/131 (2%) Frame = +2 Query: 59 FKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCL--RTFNAHKAKVEALQFN 232 F H ++ ++ H L + + +WD T + +AH A+V L FN Sbjct: 222 FTGHTAVVEDVSWHLLHESLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFN 281 Query: 233 PQNDSVGRTTFASAALDGKAKIWDI-SLILPIATLDCQSNGLIDLDYFLPGGNEQYIITG 409 P ++ + A+ + D +WD+ +L L + + + + + + + NE + + Sbjct: 282 PYSEFI----LATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQW--SPHNETILASS 335 Query: 410 SLSGNARIWNL 442 +W+L Sbjct: 336 GTDRRLNVWDL 346
>RBBP4_BOVIN (Q3MHL3) Histone-binding protein RBBP4 (Retinoblastoma-binding| protein 4) (RBBP-4) Length = 424 Score = 47.4 bits (111), Expect = 4e-05 Identities = 32/120 (26%), Positives = 57/120 (47%) Frame = +2 Query: 65 AHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQND 244 AH + L+ +P +L+ G + LWD L +F +HK ++ +Q++P N+ Sbjct: 270 AHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNE 329 Query: 245 SVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGN 424 T AS+ D + +WD+S I + + +G +L F+ GG+ I S + N Sbjct: 330 ----TILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPEL-LFIHGGHTAKISDFSWNPN 384 Score = 34.3 bits (77), Expect = 0.34 Identities = 25/131 (19%), Positives = 54/131 (41%), Gaps = 3/131 (2%) Frame = +2 Query: 59 FKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCL--RTFNAHKAKVEALQFN 232 F H ++ ++ H L + + +WD T + +AH A+V L FN Sbjct: 222 FTGHTAVVEDVSWHLLHESLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFN 281 Query: 233 PQNDSVGRTTFASAALDGKAKIWDI-SLILPIATLDCQSNGLIDLDYFLPGGNEQYIITG 409 P ++ + A+ + D +WD+ +L L + + + + + + + NE + + Sbjct: 282 PYSEFI----LATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQW--SPHNETILASS 335 Query: 410 SLSGNARIWNL 442 +W+L Sbjct: 336 GTDRRLNVWDL 346
>PRP4_PONPY (Q5NVD0) U4/U6 small nuclear ribonucleoprotein Prp4 (U4/U6 snRNP 60| kDa protein) (WD splicing factor Prp4) Length = 521 Score = 47.4 bits (111), Expect = 4e-05 Identities = 35/145 (24%), Positives = 60/145 (41%), Gaps = 7/145 (4%) Frame = +2 Query: 62 KAHNGWIQALAVHPSLPLLLS------GGCN-QGLIKLWDWEKGWTCLRTFNAHKAKVEA 220 + HN + A+ HP + L C G +KLW + + H +V Sbjct: 269 RGHNTNVGAIVFHPKSTVSLDQKDVNLASCAADGSVKLWSLDSDEP-VADIEGHTVRVAR 327 Query: 221 LQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYI 400 + ++P +G T + D ++WD+ I + S G+ D+ + G Sbjct: 328 VMWHPSGRFLGTTCY-----DRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAG-- 380 Query: 401 ITGSLSGNARIWNLRTHKCIRVIKG 475 TG L R+W+LRT +CI ++G Sbjct: 381 -TGGLDAFGRVWDLRTGRCIMFLEG 404 Score = 39.7 bits (91), Expect = 0.008 Identities = 35/142 (24%), Positives = 55/142 (38%) Frame = +2 Query: 44 EEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEAL 223 E V + H + + HPS L C +LWD E L H V + Sbjct: 313 EPVADIEGHTVRVARVMWHPS-GRFLGTTCYDRSWRLWDLEAQEEILHQ-EGHSMGVYDI 370 Query: 224 QFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYII 403 F+ G + LD ++WD+ I L+ + ++ F P G +I Sbjct: 371 AFHQDGSLAG-----TGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGIN-FSPNG--YHIA 422 Query: 404 TGSLSGNARIWNLRTHKCIRVI 469 TGS ++W+LR +C+ I Sbjct: 423 TGSGDNTCKVWDLRQRRCVYTI 444
>PRP4_MOUSE (Q9DAW6) U4/U6 small nuclear ribonucleoprotein Prp4 (U4/U6 snRNP 60| kDa protein) (WD splicing factor Prp4) Length = 521 Score = 47.4 bits (111), Expect = 4e-05 Identities = 35/145 (24%), Positives = 60/145 (41%), Gaps = 7/145 (4%) Frame = +2 Query: 62 KAHNGWIQALAVHPSLPLLLS------GGCN-QGLIKLWDWEKGWTCLRTFNAHKAKVEA 220 + HN + A+ HP + L C G +KLW + + H +V Sbjct: 269 RGHNTNVGAIVFHPKSTVSLDQKDVNLASCAADGSVKLWSLDSDEP-VADIEGHTVRVAR 327 Query: 221 LQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYI 400 + ++P +G T + D ++WD+ I + S G+ D+ + G Sbjct: 328 VMWHPSGRFLGTTCY-----DRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAG-- 380 Query: 401 ITGSLSGNARIWNLRTHKCIRVIKG 475 TG L R+W+LRT +CI ++G Sbjct: 381 -TGGLDAFGRVWDLRTGRCIMFLEG 404 Score = 39.7 bits (91), Expect = 0.008 Identities = 35/142 (24%), Positives = 55/142 (38%) Frame = +2 Query: 44 EEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEAL 223 E V + H + + HPS L C +LWD E L H V + Sbjct: 313 EPVADIEGHTVRVARVMWHPS-GRFLGTTCYDRSWRLWDLEAQEEILHQ-EGHSMGVYDI 370 Query: 224 QFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYII 403 F+ G + LD ++WD+ I L+ + ++ F P G +I Sbjct: 371 AFHQDGSLAG-----TGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGIN-FSPNG--YHIA 422 Query: 404 TGSLSGNARIWNLRTHKCIRVI 469 TGS ++W+LR +C+ I Sbjct: 423 TGSGDNTCKVWDLRQRRCVYTI 444
>KTNB1_HUMAN (Q9BVA0) Katanin p80 WD40-containing subunit B1 (Katanin p80| subunit B1) (p80 katanin) Length = 655 Score = 47.4 bits (111), Expect = 4e-05 Identities = 43/161 (26%), Positives = 69/161 (42%), Gaps = 3/161 (1%) Frame = +2 Query: 2 VMGXPPAXCKTLGLEEVKKFKA---HNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKG 172 V G + LE K + H I +L HP + SG + IKLWD + Sbjct: 79 VAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTN-IKLWDIRRK 137 Query: 173 WTCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNG 352 C+ + H V L+F+P + ASAA D K+WD++ ++ + G Sbjct: 138 G-CVFRYRGHSQAVRCLRFSPDGKWL-----ASAADDHTVKLWDLTAGKMMSEFPGHT-G 190 Query: 353 LIDLDYFLPGGNEQYIITGSLSGNARIWNLRTHKCIRVIKG 475 +++ F P NE + +GS R W+L + + I+G Sbjct: 191 PVNVVEFHP--NEYLLASGSSDRTIRFWDLEKFQVVSCIEG 229 Score = 42.0 bits (97), Expect = 0.002 Identities = 24/64 (37%), Positives = 33/64 (51%) Frame = +2 Query: 116 LLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAK 295 L+ G G I++WD E LRT HKA + +L F+P + V AS + D K Sbjct: 77 LIVAGSQSGSIRVWDLEAA-KILRTLMGHKANICSLDFHPYGEFV-----ASGSQDTNIK 130 Query: 296 IWDI 307 +WDI Sbjct: 131 LWDI 134 Score = 32.3 bits (72), Expect = 1.3 Identities = 18/62 (29%), Positives = 30/62 (48%) Frame = +2 Query: 50 VKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQF 229 + +F H G + + HP+ LL SG ++ I+ WD EK + + V ++ F Sbjct: 182 MSEFPGHTGPVNVVEFHPNEYLLASGSSDR-TIRFWDLEK-FQVVSCIEGEPGPVRSVLF 239 Query: 230 NP 235 NP Sbjct: 240 NP 241
>KTNB1_CHICK (Q5ZIU8) Katanin p80 WD40-containing subunit B1 (Katanin p80| subunit B1) (p80 katanin) Length = 657 Score = 47.0 bits (110), Expect = 5e-05 Identities = 41/181 (22%), Positives = 82/181 (45%) Frame = +2 Query: 47 EVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQ 226 ++++ AH+ + +L + S LL+ G + + +W + H +E+LQ Sbjct: 12 KLQEIVAHSSNVSSLVLGKSTGRLLATGGDDCQVNVWSVKA--QLRHELTGHTTPIESLQ 69 Query: 227 FNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIIT 406 + + + + + + G ++WD+ + TL + LD F P G+ ++ + Sbjct: 70 ISAKEELI-----VAGSQSGSIRVWDLEAAKILRTLLGHKANICSLD-FHPYGS--FVAS 121 Query: 407 GSLSGNARIWNLRTHKCIRVIKGTSITSGAGCSVRVVYCSPDPPLLIRTFEDDSLGLCNS 586 GSL + ++W++R CI K S T +VR + SPD L +D ++ L + Sbjct: 122 GSLDTDIKLWDVRRKGCI--FKYKSHTQ----AVRCLRFSPDGKWLASAADDHTVKLWDL 175 Query: 587 T 589 T Sbjct: 176 T 176 Score = 32.7 bits (73), Expect = 0.98 Identities = 19/60 (31%), Positives = 29/60 (48%) Frame = +2 Query: 56 KFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNP 235 +F H+G + + HPS LL SG ++ I+ WD EK + + V + FNP Sbjct: 183 EFTGHSGPVNVVEFHPSEYLLASGSSDR-TIRFWDLEK-FHVVSCIEEEATPVRCILFNP 240
>GBB_SCHPO (Q10282) Guanine nucleotide-binding protein beta subunit| Length = 305 Score = 47.0 bits (110), Expect = 5e-05 Identities = 43/160 (26%), Positives = 67/160 (41%), Gaps = 4/160 (2%) Frame = +2 Query: 8 GXPPAXCKTLGLEEVKKF---KAHNGWIQALAVHPSLP-LLLSGGCNQGLIKLWDWEKGW 175 G C +E+ K K H I +L PS P L ++GGC++ L KLWD + Sbjct: 123 GSGDKTCMFWDIEQAKAISVLKGHEMDIVSLDFLPSNPNLFVTGGCDK-LAKLWDLRAAY 181 Query: 176 TCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGL 355 C TF + + + ++ F P N F + A DG A+ +DI I S+ Sbjct: 182 -CCATFPGNTSDINSISFFPSN-----ADFVTGAEDGIARCFDIRASAEIFQYSSPSSSP 235 Query: 356 IDLDYFLPGGNEQYIITGSLSGNARIWNLRTHKCIRVIKG 475 I+ F G +I + +W+ + K I + G Sbjct: 236 INSVLFSKSGKLLFI---AKDKTCEVWDSISSKTITSLTG 272 Score = 38.5 bits (88), Expect = 0.018 Identities = 35/145 (24%), Positives = 55/145 (37%) Frame = +2 Query: 47 EVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQ 226 +V F+A + WI A PS + +GG N + ++D H V + Sbjct: 55 KVAFFEAPSVWIMTCAFSPSTKSIAAGGLNNFCV-VYDTSVPDADPVELVGHAGFVSCCK 113 Query: 227 FNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIIT 406 + V + + D WDI I+ L ++ LD FLP N +T Sbjct: 114 Y------VDDGHLLTGSGDKTCMFWDIEQAKAISVLKGHEMDIVSLD-FLPS-NPNLFVT 165 Query: 407 GSLSGNARIWNLRTHKCIRVIKGTS 481 G A++W+LR C G + Sbjct: 166 GGCDKLAKLWDLRAAYCCATFPGNT 190
>A16L1_MOUSE (Q8C0J2) Autophagy-related protein 16-1 (APG16-like 1)| Length = 607 Score = 47.0 bits (110), Expect = 5e-05 Identities = 44/176 (25%), Positives = 79/176 (44%), Gaps = 4/176 (2%) Frame = +2 Query: 2 VMGXPPAXCKTLGLEEVKK--FKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGW 175 +M PA K + + F AH+G + A+ P LL +GG ++ +KLW+ G Sbjct: 297 IMDTHPASGKDVRVPTTASYVFDAHDGEVNAVQFSPGSRLLATGGMDRR-VKLWE-AFGD 354 Query: 176 TC--LRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSN 349 C + + A + +++F DS G A A+ D ++IW + TL S Sbjct: 355 KCEFKGSLSGSNAGITSIEF----DSAGAYLLA-ASNDFASRIWTVDDYRLRHTLTGHSG 409 Query: 350 GLIDLDYFLPGGNEQYIITGSLSGNARIWNLRTHKCIRVIKGTSITSGAGCSVRVV 517 ++ + L I++GS ++W+LR+ CI+ + S + C+ + V Sbjct: 410 KVLSAKFLLDNAR---IVSGSHDRTLKLWDLRSKVCIKTVFAGSSCNDIVCTEQCV 462
>NLE1_BOVIN (Q58D20) Notchless homolog 1| Length = 485 Score = 47.0 bits (110), Expect = 5e-05 Identities = 32/138 (23%), Positives = 56/138 (40%) Frame = +2 Query: 62 KAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQN 241 + H W+ +++ P L SG C G I LWD G R H + AL + P + Sbjct: 153 QGHRHWVLSISWSPDGKKLASG-CKNGQILLWDPSTGKQVGRALTGHSKWITALSWEPLH 211 Query: 242 DSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSG 421 + AS++ DG ++WD + TL + + L + G + + + S Sbjct: 212 ANPECRYVASSSKDGSVRVWDTTAGRCERTLTGHAQSVTCLRW----GGDGLLYSASQDR 267 Query: 422 NARIWNLRTHKCIRVIKG 475 ++W R ++G Sbjct: 268 TIKVWRAHDGVLCRTLQG 285 Score = 33.1 bits (74), Expect = 0.75 Identities = 23/115 (20%), Positives = 48/115 (41%) Frame = +2 Query: 110 PLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGK 289 P L G + + LW + L H+A + + F+P + ASA+ D Sbjct: 341 PERLVSGSDDFTLFLWSPAEDKKPLARMTGHQALINQVVFSPDS-----RVIASASFDKS 395 Query: 290 AKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNARIWNLRTHK 454 K+WD +A+L + + + + + +++GS ++W+++ K Sbjct: 396 IKLWDGRTGKYLASLRGHVAAVYQIAW---SADSRLLVSGSSDSTLKVWDVKAQK 447
>PWP2_YEAST (P25635) Periodic tryptophan protein 2 (U3 small nucleolar| RNA-associated protein 1) (U3 snoRNA-associated protein 1) Length = 923 Score = 47.0 bits (110), Expect = 5e-05 Identities = 31/133 (23%), Positives = 61/133 (45%) Frame = +2 Query: 80 IQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRT 259 + ++V+ + L G G + +++W+ L+ H +L ++P V Sbjct: 305 VNTVSVNQTGEWLAFGSSKLGQLLVYEWQSESYILKQ-QGHFDSTNSLAYSPDGSRV--- 360 Query: 260 TFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNARIWN 439 +A+ DGK K+WDI+ +AT + ++ + + + G Q + + SL G R W+ Sbjct: 361 --VTASEDGKIKVWDITSGFCLATFEEHTSSVTAVQFAKRG---QVMFSSSLDGTVRAWD 415 Query: 440 LRTHKCIRVIKGT 478 L ++ R GT Sbjct: 416 LIRYRNFRTFTGT 428
>LIS1_BOVIN (P43033) Platelet-activating factor acetylhydrolase IB alpha| subunit (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1) Length = 409 Score = 46.6 bits (109), Expect = 7e-05 Identities = 34/136 (25%), Positives = 60/136 (44%) Frame = +2 Query: 68 HNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDS 247 H + + HP +++S IK+WD+E G RT H VE + F D Sbjct: 106 HRSPVTRVIFHPVFSVMVSAS-EDATIKVWDYETG-DFERTLKGHTDSVEDISF----DH 159 Query: 248 VGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNA 427 G+ AS + D K+WD I T+ + + + +P G+ +I++ S Sbjct: 160 SGKL-LASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVA-IMPNGD--HIVSASRDKTI 215 Query: 428 RIWNLRTHKCIRVIKG 475 ++W ++T C++ G Sbjct: 216 KMWEVQTGYCVKTFTG 231 Score = 43.9 bits (102), Expect = 4e-04 Identities = 32/112 (28%), Positives = 49/112 (43%) Frame = +2 Query: 110 PLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGK 289 P LLSG ++ IK+WD G CL T H V + F+ G S A D Sbjct: 308 PFLLSGSRDK-TIKMWDVSTGM-CLMTLVGHDNWVRGVLFHS-----GGKFILSCADDKT 360 Query: 290 AKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNARIWNLR 445 ++WD + TL+ + + LD+ Y++TGS+ ++W R Sbjct: 361 LRVWDYKNKRCMKTLNAHEHFVTSLDFHKTA---PYVVTGSVDQTVKVWECR 409 Score = 38.1 bits (87), Expect = 0.023 Identities = 21/79 (26%), Positives = 41/79 (51%) Frame = +2 Query: 68 HNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDS 247 H+ W++ + H +LS ++ L ++WD+ K C++T NAH+ V +L F+ Sbjct: 336 HDNWVRGVLFHSGGKFILSCADDKTL-RVWDY-KNKRCMKTLNAHEHFVTSLDFHKTAPY 393 Query: 248 VGRTTFASAALDGKAKIWD 304 V + ++D K+W+ Sbjct: 394 V-----VTGSVDQTVKVWE 407
>NLE1_MOUSE (Q8VEJ4) Notchless homolog 1| Length = 484 Score = 46.6 bits (109), Expect = 7e-05 Identities = 25/81 (30%), Positives = 37/81 (45%) Frame = +2 Query: 62 KAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQN 241 K H W+ +++ P L SG C G I LWD G RT H + L + P + Sbjct: 152 KGHRHWVLSISWSPDGKKLASG-CKNGQILLWDPSTGLQVGRTLTGHSKWITGLSWEPLH 210 Query: 242 DSVGRTTFASAALDGKAKIWD 304 + AS++ DG ++WD Sbjct: 211 MNPECRYVASSSKDGSVRVWD 231 Score = 33.9 bits (76), Expect = 0.44 Identities = 25/122 (20%), Positives = 51/122 (41%) Frame = +2 Query: 110 PLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGK 289 P L G + + LW + L H+A + + F+P + V ASA+ D Sbjct: 340 PERLVSGSDDFTLFLWSPAEDKKPLARMTGHQALINQVLFSPDSRIV-----ASASFDKS 394 Query: 290 AKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNARIWNLRTHKCIRVI 469 K+WD +A+L + + + + + +++GS ++W+++ K + Sbjct: 395 IKLWDGRTGKYLASLRGHVAAVYQIAW---SADSRLLVSGSSDSTLKVWDVKAQKLATDL 451 Query: 470 KG 475 G Sbjct: 452 PG 453
>MEP50_MOUSE (Q99J09) Methylosome protein 50 (MEP50 protein) (WD-repeat protein| 77) Length = 342 Score = 46.6 bits (109), Expect = 7e-05 Identities = 36/154 (23%), Positives = 65/154 (42%) Frame = +2 Query: 128 GCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDI 307 G IK+WD + L ++ AH +V + +P DSV F S + D + +WD Sbjct: 143 GSKDCCIKIWDLAQQ-VSLNSYRAHAGQVTCVAASPHKDSV----FLSCSEDSRILLWDT 197 Query: 308 SLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNARIWNLRTHKCIRVIKGTSIT 487 P + + C ++G + + + G +G+ + + + C +S Sbjct: 198 RCPKPASQMACNASGYLPTALAWHPQQSEVFVFGDENGSVSLVDTKNASCTL----SSAV 253 Query: 488 SGAGCSVRVVYCSPDPPLLIRTFEDDSLGLCNST 589 G + R+V+ PLL ED SL + +S+ Sbjct: 254 HSQGVT-RLVFSPHSVPLLTSLSEDCSLAVLDSS 286
>PRP46_CRYNE (Q5KDR4) Pre-mRNA-splicing factor PRP46 (Pre-mRNA-processing| protein 46) Length = 473 Score = 46.6 bits (109), Expect = 7e-05 Identities = 34/134 (25%), Positives = 61/134 (45%) Frame = +2 Query: 68 HNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDS 247 H I+ LAV P L S ++ ++K WD E +R ++ H + V +L +P D Sbjct: 223 HISTIRGLAVSDRHPYLFSCAEDK-MVKCWDLETN-KVIRHYHGHFSGVYSLSVHPTLD- 279 Query: 248 VGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNA 427 + D ++WD+ I TL ++ + D+ ++ II+GS+ Sbjct: 280 ----VLVTGGRDASVRVWDMRTRANIFTLTGHTSTVGDVK---TQDSDPQIISGSMDSTV 332 Query: 428 RIWNLRTHKCIRVI 469 R+W+L KC+ + Sbjct: 333 RLWDLAAGKCMNTL 346 Score = 44.3 bits (103), Expect = 3e-04 Identities = 34/142 (23%), Positives = 61/142 (42%) Frame = +2 Query: 68 HNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDS 247 H GW++A+A+ P +G ++ +IK+WD G L + H + + L + ++ Sbjct: 181 HMGWVRAVAMDPGNQWFATGAGDR-VIKIWDLASGELKL-SLTGHISTIRGLAVSDRHPY 238 Query: 248 VGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNA 427 + S A D K WD+ I +G+ L ++TG + Sbjct: 239 L-----FSCAEDKMVKCWDLETNKVIRHYHGHFSGVYSLSVH---PTLDVLVTGGRDASV 290 Query: 428 RIWNLRTHKCIRVIKGTSITSG 493 R+W++RT I + G + T G Sbjct: 291 RVWDMRTRANIFTLTGHTSTVG 312 Score = 37.0 bits (84), Expect = 0.052 Identities = 28/101 (27%), Positives = 41/101 (40%), Gaps = 1/101 (0%) Frame = +2 Query: 68 HNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDS 247 H ++ALA+HP+ S IK W +G + F H+A + L N +N Sbjct: 349 HKKSVRALAIHPTEYSFASASSGGNNIKKWKCPEG-IFVNNFVGHEAIINTLSINSEN-- 405 Query: 248 VGRTTFASAALDGKAKIWDISLILPIATL-DCQSNGLIDLD 367 S A +G +WD LP L D G +D + Sbjct: 406 ----VLFSGADNGTLTLWDYKTGLPFQHLKDIPQPGSLDAE 442 Score = 35.8 bits (81), Expect = 0.12 Identities = 18/87 (20%), Positives = 44/87 (50%) Frame = +2 Query: 50 VKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQF 229 ++ + H + +L+VHP+L +L++GG +++WD + + T H + V ++ Sbjct: 259 IRHYHGHFSGVYSLSVHPTLDVLVTGG-RDASVRVWDM-RTRANIFTLTGHTSTVGDVKT 316 Query: 230 NPQNDSVGRTTFASAALDGKAKIWDIS 310 + + S ++D ++WD++ Sbjct: 317 QDSDPQI-----ISGSMDSTVRLWDLA 338
>Y163_SYNY3 (Q55563) Hypothetical WD-repeat protein sll0163| Length = 1693 Score = 46.6 bits (109), Expect = 7e-05 Identities = 40/144 (27%), Positives = 66/144 (45%) Frame = +2 Query: 44 EEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEAL 223 E++ + H W++ + +LL+ G +LWD E L H + V Sbjct: 1128 EQLTLCQGHADWVRNAEFNCHGQILLTAS-RDGTARLWDLEGREIGL--CQGHTSWVRNA 1184 Query: 224 QFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYII 403 QF+P + + + DG A++WD+S A L N ++ + P G Q+II Sbjct: 1185 QFSPDGQWI-----VTCSADGTARLWDLSSQC-FAVLKGHQNW-VNNALWSPDG--QHII 1235 Query: 404 TGSLSGNARIWNLRTHKCIRVIKG 475 T S G AR+W+ R KC+ ++G Sbjct: 1236 TSSSDGTARVWS-RHGKCLGTLRG 1258 Score = 45.4 bits (106), Expect = 1e-04 Identities = 38/145 (26%), Positives = 64/145 (44%), Gaps = 1/145 (0%) Frame = +2 Query: 44 EEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEAL 223 EEV + H W++++ P L++ G ++W++ L H V Sbjct: 1087 EEVATLRGHEDWVRSVHFSPHHQFLVTSG-QDNTARIWNF--AGEQLTLCQGHADWVRNA 1143 Query: 224 QFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSN-GLIDLDYFLPGGNEQYI 400 +FN +A+ DG A++WD+ CQ + + F P G Q+I Sbjct: 1144 EFNCHGQ-----ILLTASRDGTARLWDLE---GREIGLCQGHTSWVRNAQFSPDG--QWI 1193 Query: 401 ITGSLSGNARIWNLRTHKCIRVIKG 475 +T S G AR+W+L + +C V+KG Sbjct: 1194 VTCSADGTARLWDL-SSQCFAVLKG 1217 Score = 38.9 bits (89), Expect = 0.014 Identities = 29/124 (23%), Positives = 57/124 (45%) Frame = +2 Query: 68 HNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDS 247 H+ W++ +P LL+ ++ +LW E C+ H+ V QF+P Sbjct: 1341 HSHWVRNAHFNPKGDRLLTVSRDK-TARLWTTEG--ECVAVLADHQGWVREGQFSPDGQW 1397 Query: 248 VGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNA 427 + + + D A++W++ L + L + ++++ + + QYI+T S G A Sbjct: 1398 I-----VTGSADKTAQLWNV-LGKKLTVLRGHQDAVLNVRF---SPDSQYIVTASKDGTA 1448 Query: 428 RIWN 439 R+WN Sbjct: 1449 RVWN 1452 Score = 38.5 bits (88), Expect = 0.018 Identities = 23/96 (23%), Positives = 48/96 (50%) Frame = +2 Query: 161 WEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDC 340 W++ + H+ V + ++P + +A+ DG A++WD+S + TL+ Sbjct: 1574 WDRSGKTVAVLYGHQGLVGTVDWSPDGQML-----VTASNDGTARLWDLS-GRELLTLEG 1627 Query: 341 QSNGLIDLDYFLPGGNEQYIITGSLSGNARIWNLRT 448 N + + F P G ++++T S G A++W ++T Sbjct: 1628 HGNWVRSAE-FSPDG--RWVLTSSADGTAKLWPVKT 1660 Score = 38.1 bits (87), Expect = 0.023 Identities = 34/134 (25%), Positives = 56/134 (41%) Frame = +2 Query: 188 TFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLD 367 T H V FNP+ D + + + D A++W D Q G + Sbjct: 1337 TLTGHSHWVRNAHFNPKGDRL-----LTVSRDKTARLWTTEGECVAVLADHQ--GWVREG 1389 Query: 368 YFLPGGNEQYIITGSLSGNARIWNLRTHKCIRVIKGTSITSGAGCSVRVVYCSPDPPLLI 547 F P G Q+I+TGS A++WN+ + K ++ G +V V SPD ++ Sbjct: 1390 QFSPDG--QWIVTGSADKTAQLWNV-------LGKKLTVLRGHQDAVLNVRFSPDSQYIV 1440 Query: 548 RTFEDDSLGLCNST 589 +D + + N+T Sbjct: 1441 TASKDGTARVWNNT 1454
>GBB1_HOMAM (O45040) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 340 Score = 46.6 bits (109), Expect = 7e-05 Identities = 25/88 (28%), Positives = 46/88 (52%) Frame = +2 Query: 44 EEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEAL 223 ++ +F H G + +L++ P++ SG C+ KLWD G C +TF H++ + A+ Sbjct: 175 QQCTQFTGHTGDVMSLSLSPNMRTFTSGACDAS-AKLWDIRDG-MCRQTFPGHESDINAV 232 Query: 224 QFNPQNDSVGRTTFASAALDGKAKIWDI 307 F P + FA+ + D +++DI Sbjct: 233 TFFPNGHA-----FATGSDDATCRLFDI 255
>GBB1_CAEEL (P17343) Guanine nucleotide-binding protein beta subunit 1| Length = 340 Score = 46.6 bits (109), Expect = 7e-05 Identities = 25/88 (28%), Positives = 45/88 (51%) Frame = +2 Query: 44 EEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEAL 223 ++ F H G + +L++ P +SG C+ KLWD G C +TF H++ + A+ Sbjct: 175 QQCTAFTGHTGDVMSLSLSPDFRTFISGACDAS-AKLWDIRDG-MCKQTFPGHESDINAV 232 Query: 224 QFNPQNDSVGRTTFASAALDGKAKIWDI 307 F P ++ FA+ + D +++DI Sbjct: 233 AFFPSGNA-----FATGSDDATCRLFDI 255
>GBB1_CAEBR (Q61ZF6) Guanine nucleotide-binding protein beta subunit 1| Length = 340 Score = 46.6 bits (109), Expect = 7e-05 Identities = 25/88 (28%), Positives = 45/88 (51%) Frame = +2 Query: 44 EEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEAL 223 ++ F H G + +L++ P +SG C+ KLWD G C +TF H++ + A+ Sbjct: 175 QQCTAFTGHTGDVMSLSLSPDFRTFISGACDAS-AKLWDIRDG-MCKQTFPGHESDINAV 232 Query: 224 QFNPQNDSVGRTTFASAALDGKAKIWDI 307 F P ++ FA+ + D +++DI Sbjct: 233 AFFPSGNA-----FATGSDDATCRLFDI 255
>A16L1_HUMAN (Q676U5) Autophagy-related protein 16-1 (APG16-like 1)| Length = 607 Score = 46.6 bits (109), Expect = 7e-05 Identities = 40/155 (25%), Positives = 72/155 (46%), Gaps = 2/155 (1%) Frame = +2 Query: 59 FKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTC--LRTFNAHKAKVEALQFN 232 F AH+G + A+ P LL +GG ++ +KLW+ G C + + A + +++F Sbjct: 318 FDAHDGEVNAVQFSPGSRLLATGGMDRR-VKLWE-VFGEKCEFKGSLSGSNAGITSIEF- 374 Query: 233 PQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGS 412 DS G A A+ D ++IW + TL S ++ + L I++GS Sbjct: 375 ---DSAGSYLLA-ASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNAR---IVSGS 427 Query: 413 LSGNARIWNLRTHKCIRVIKGTSITSGAGCSVRVV 517 ++W+LR+ CI+ + S + C+ + V Sbjct: 428 HDRTLKLWDLRSKVCIKTVFAGSSCNDIVCTEQCV 462 Score = 37.7 bits (86), Expect = 0.030 Identities = 25/104 (24%), Positives = 48/104 (46%), Gaps = 2/104 (1%) Frame = +2 Query: 176 TCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDI--SLILPIATLDCQSN 349 T L F+AH +V A+QF+P G A+ +D + K+W++ +L + Sbjct: 313 TALCVFDAHDGEVNAVQFSP-----GSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNA 367 Query: 350 GLIDLDYFLPGGNEQYIITGSLSGNARIWNLRTHKCIRVIKGTS 481 G+ +++ G Y++ S +RIW + ++ + G S Sbjct: 368 GITSIEFDSAG---SYLLAASNDFASRIWTVDDYRLRHTLTGHS 408
>RBBP7_XENTR (Q6P315) Histone-binding protein RBBP7 (Retinoblastoma-binding| protein 7) (RBBP-7) Length = 425 Score = 46.2 bits (108), Expect = 9e-05 Identities = 31/120 (25%), Positives = 56/120 (46%) Frame = +2 Query: 65 AHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQND 244 AH + L+ +P +L+ G + LWD L +F +HK ++ + ++P N+ Sbjct: 270 AHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVHWSPHNE 329 Query: 245 SVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGN 424 T AS+ D + +WD+S I + + +G +L F+ GG+ I S + N Sbjct: 330 ----TILASSGTDRRLNVWDLSKIGEEQSAEDAEDGPPEL-LFIHGGHTAKISDFSWNPN 384 Score = 36.2 bits (82), Expect = 0.088 Identities = 26/131 (19%), Positives = 55/131 (41%), Gaps = 3/131 (2%) Frame = +2 Query: 59 FKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCL--RTFNAHKAKVEALQFN 232 F H+ ++ +A H L + + +WD T + +AH A+V L FN Sbjct: 222 FTGHSAVVEDVAWHLLHESLFGSVADDQKLMIWDTRSNTTSKPSHSVDAHTAEVNCLSFN 281 Query: 233 PQNDSVGRTTFASAALDGKAKIWDI-SLILPIATLDCQSNGLIDLDYFLPGGNEQYIITG 409 P ++ + A+ + D +WD+ +L L + + + + + + + NE + + Sbjct: 282 PYSEFI----LATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVHW--SPHNETILASS 335 Query: 410 SLSGNARIWNL 442 +W+L Sbjct: 336 GTDRRLNVWDL 346
>RBBP7_XENLA (Q8AVH1) Histone-binding protein RBBP7 (Retinoblastoma-binding| protein 7) (RBBP-7) Length = 425 Score = 46.2 bits (108), Expect = 9e-05 Identities = 31/120 (25%), Positives = 56/120 (46%) Frame = +2 Query: 65 AHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQND 244 AH + L+ +P +L+ G + LWD L +F +HK ++ + ++P N+ Sbjct: 270 AHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVHWSPHNE 329 Query: 245 SVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGN 424 T AS+ D + +WD+S I + + +G +L F+ GG+ I S + N Sbjct: 330 ----TILASSGTDRRLNVWDLSKIGEEQSAEDAEDGPPEL-LFIHGGHTAKISDFSWNPN 384 Score = 36.2 bits (82), Expect = 0.088 Identities = 26/131 (19%), Positives = 55/131 (41%), Gaps = 3/131 (2%) Frame = +2 Query: 59 FKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCL--RTFNAHKAKVEALQFN 232 F H+ ++ +A H L + + +WD T + +AH A+V L FN Sbjct: 222 FTGHSAVVEDVAWHLLHESLFGSVADDQKLMIWDTRSNTTSKPSHSVDAHTAEVNCLSFN 281 Query: 233 PQNDSVGRTTFASAALDGKAKIWDI-SLILPIATLDCQSNGLIDLDYFLPGGNEQYIITG 409 P ++ + A+ + D +WD+ +L L + + + + + + + NE + + Sbjct: 282 PYSEFI----LATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVHW--SPHNETILASS 335 Query: 410 SLSGNARIWNL 442 +W+L Sbjct: 336 GTDRRLNVWDL 346
>GBB_LYMST (Q08706) Guanine nucleotide-binding protein beta subunit| Length = 341 Score = 46.2 bits (108), Expect = 9e-05 Identities = 24/88 (27%), Positives = 44/88 (50%) Frame = +2 Query: 44 EEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEAL 223 ++ F H G + +L+ P +SG C+ KLWD G C +TF+ H++ + A+ Sbjct: 176 QQTTSFTGHTGDVMSLSTSPDFRTFVSGACDAS-AKLWDVRDG-MCKQTFSGHESDINAI 233 Query: 224 QFNPQNDSVGRTTFASAALDGKAKIWDI 307 + P + FA+ + D +++DI Sbjct: 234 TYFPNGHA-----FATGSDDATCRLFDI 256 Score = 41.6 bits (96), Expect = 0.002 Identities = 41/170 (24%), Positives = 68/170 (40%) Frame = +2 Query: 53 KKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFN 232 ++ H G++ ++ S G LWD E G +F H V +L + Sbjct: 138 RELPGHTGYLSCCRFIDDNSIVTSSGDMS--CALWDIETGQQTT-SFTGHTGDVMSLSTS 194 Query: 233 PQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGS 412 P TF S A D AK+WD+ + T + + + YF P G+ TGS Sbjct: 195 PDF-----RTFVSGACDASAKLWDVRDGMCKQTFSGHESDINAITYF-PNGHA--FATGS 246 Query: 413 LSGNARIWNLRTHKCIRVIKGTSITSGAGCSVRVVYCSPDPPLLIRTFED 562 R++++R + I + +I C + V S LL+ ++D Sbjct: 247 DDATCRLFDIRADQEIGMYSHDNII----CGITSVAFSKSGRLLLGRYDD 292
>RBBP7_CHICK (Q9I8G9) Histone-binding protein RBBP7 (Retinoblastoma-binding| protein 7) (RBBP-7) (Retinoblastoma-binding protein p46) Length = 424 Score = 46.2 bits (108), Expect = 9e-05 Identities = 31/120 (25%), Positives = 56/120 (46%) Frame = +2 Query: 65 AHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQND 244 AH + L+ +P +L+ G + LWD L +F +HK ++ + ++P N+ Sbjct: 269 AHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVHWSPHNE 328 Query: 245 SVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGN 424 T AS+ D + +WD+S I + + +G +L F+ GG+ I S + N Sbjct: 329 ----TILASSGTDRRLNVWDLSKIGEEQSAEDAEDGPPEL-LFIHGGHTAKISDFSWNPN 383 Score = 36.2 bits (82), Expect = 0.088 Identities = 26/131 (19%), Positives = 55/131 (41%), Gaps = 3/131 (2%) Frame = +2 Query: 59 FKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCL--RTFNAHKAKVEALQFN 232 F H+ ++ +A H L + + +WD T + +AH A+V L FN Sbjct: 221 FTGHSAVVEDVAWHLLHESLFGSVADDQKLMIWDTRSNTTSKPSHSVDAHTAEVNCLSFN 280 Query: 233 PQNDSVGRTTFASAALDGKAKIWDI-SLILPIATLDCQSNGLIDLDYFLPGGNEQYIITG 409 P ++ + A+ + D +WD+ +L L + + + + + + + NE + + Sbjct: 281 PYSEFI----LATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVHW--SPHNETILASS 334 Query: 410 SLSGNARIWNL 442 +W+L Sbjct: 335 GTDRRLNVWDL 345
>Y2124_ANASP (Q8YV57) Hypothetical WD-repeat protein all2124| Length = 1683 Score = 46.2 bits (108), Expect = 9e-05 Identities = 37/148 (25%), Positives = 62/148 (41%) Frame = +2 Query: 50 VKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQF 229 VK K HN + + + S IKLW+ + L TF H V A+ F Sbjct: 1274 VKTLKGHNDSVWDVNFSSDGKAIASAS-RDNTIKLWN--RHGIELETFTGHSGGVYAVNF 1330 Query: 230 NPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITG 409 P ++ + ASA+LD ++W LI P+ L ++G+ + + G I T Sbjct: 1331 LPDSNII-----ASASLDNTIRLWQRPLISPLEVL-AGNSGVYAVSFLHDG---SIIATA 1381 Query: 410 SLSGNARIWNLRTHKCIRVIKGTSITSG 493 GN ++W+ + ++ + G G Sbjct: 1382 GADGNIQLWHSQDGSLLKTLPGNKAIYG 1409 Score = 43.5 bits (101), Expect = 6e-04 Identities = 29/107 (27%), Positives = 51/107 (47%) Frame = +2 Query: 119 LSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKI 298 ++ G +KLW + G L+T N H+ V +L F+P T ASA+ D K+ Sbjct: 1212 IAAGSEDKTVKLWHRQDG-KLLKTLNGHQDWVNSLSFSPDGK-----TLASASADKTIKL 1265 Query: 299 WDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNARIWN 439 W I+ + TL ++ + D+++ G + I + S ++WN Sbjct: 1266 WRIADGKLVKTLKGHNDSVWDVNFSSDG---KAIASASRDNTIKLWN 1309 Score = 42.4 bits (98), Expect = 0.001 Identities = 40/192 (20%), Positives = 80/192 (41%) Frame = +2 Query: 41 LEEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEA 220 ++E + + H + ++++ + SG ++ IKLW + RT N H+ V + Sbjct: 1062 MQERNRLEGHKDGVISISISRDGQTIASGSLDK-TIKLWS--RDGRLFRTLNGHEDAVYS 1118 Query: 221 LQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYI 400 + F+P T AS D K+W S + T+ + ++ YF P G + Sbjct: 1119 VSFSPDGQ-----TIASGGSDKTIKLWQTSDGTLLKTITGHEQTVNNV-YFSPDGKN--L 1170 Query: 401 ITGSLSGNARIWNLRTHKCIRVIKGTSITSGAGCSVRVVYCSPDPPLLIRTFEDDSLGLC 580 + S + ++W+ + + + + G S V V SPD + ED ++ L Sbjct: 1171 ASASSDHSIKLWDTTSGQLLMTLTGHS------AGVITVRFSPDGQTIAAGSEDKTVKLW 1224 Query: 581 NSTTFRYTNTID 616 + + T++ Sbjct: 1225 HRQDGKLLKTLN 1236 Score = 34.3 bits (77), Expect = 0.34 Identities = 41/172 (23%), Positives = 72/172 (41%) Frame = +2 Query: 71 NGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDSV 250 N I ++ P L+ S ++ +K+W G L+T H +V + F+P Sbjct: 1404 NKAIYGISFTPQGDLIASANADK-TVKIWRVRDG-KALKTLIGHDNEVNKVNFSPDGK-- 1459 Query: 251 GRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNAR 430 T ASA+ D K+W++S TL ++ + + F P G + I + S R Sbjct: 1460 ---TLASASRDNTVKLWNVSDGKFKKTLKGHTDEVFWVS-FSPDG--KIIASASADKTIR 1513 Query: 431 IWNLRTHKCIRVIKGTSITSGAGCSVRVVYCSPDPPLLIRTFEDDSLGLCNS 586 +W+ + I+ + + V V +PD +L T D ++ L S Sbjct: 1514 LWDSFSGNLIKSLPAHNDL------VYSVNFNPDGSMLASTSADKTVKLWRS 1559
>NLE1_PONPY (Q5RFF8) Notchless homolog 1| Length = 484 Score = 46.2 bits (108), Expect = 9e-05 Identities = 26/81 (32%), Positives = 37/81 (45%) Frame = +2 Query: 62 KAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQN 241 K H W+ +++ P L SG C G I LWD G RT H + L + P + Sbjct: 152 KGHRHWVLSISWSPDGKKLASG-CKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLH 210 Query: 242 DSVGRTTFASAALDGKAKIWD 304 + AS++ DG +IWD Sbjct: 211 ANPECRYVASSSKDGSVRIWD 231 Score = 33.9 bits (76), Expect = 0.44 Identities = 25/122 (20%), Positives = 51/122 (41%) Frame = +2 Query: 110 PLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGK 289 P L G + + LW + L H+A + + F+P + V ASA+ D Sbjct: 340 PERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIV-----ASASFDKS 394 Query: 290 AKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNARIWNLRTHKCIRVI 469 K+WD +A+L + + + + + +++GS ++W+++ K + Sbjct: 395 IKLWDGRTGKYLASLRGHVAAVYQIAW---SADSRLLVSGSSDSTLKVWDVKAQKLAMDL 451 Query: 470 KG 475 G Sbjct: 452 PG 453
>NLE1_HUMAN (Q9NVX2) Notchless homolog 1| Length = 484 Score = 46.2 bits (108), Expect = 9e-05 Identities = 26/81 (32%), Positives = 37/81 (45%) Frame = +2 Query: 62 KAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQN 241 K H W+ +++ P L SG C G I LWD G RT H + L + P + Sbjct: 152 KGHRHWVLSISWSPDGKKLASG-CKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLH 210 Query: 242 DSVGRTTFASAALDGKAKIWD 304 + AS++ DG +IWD Sbjct: 211 ANPECRYVASSSKDGSVRIWD 231 Score = 33.9 bits (76), Expect = 0.44 Identities = 25/122 (20%), Positives = 51/122 (41%) Frame = +2 Query: 110 PLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGK 289 P L G + + LW + L H+A + + F+P + V ASA+ D Sbjct: 340 PERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIV-----ASASFDKS 394 Query: 290 AKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNARIWNLRTHKCIRVI 469 K+WD +A+L + + + + + +++GS ++W+++ K + Sbjct: 395 IKLWDGRTGKYLASLRGHVAAVYQIAW---SADSRLLVSGSSDSTLKVWDVKAQKLAMDL 451 Query: 470 KG 475 G Sbjct: 452 PG 453
>WDR48_BRARE (Q6PFM9) WD-repeat protein 48| Length = 677 Score = 45.8 bits (107), Expect = 1e-04 Identities = 39/148 (26%), Positives = 68/148 (45%), Gaps = 6/148 (4%) Frame = +2 Query: 50 VKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQF 229 + + H W+ + + + L+S + +K+W+ KG+ C+ T HK V+AL + Sbjct: 68 IASMEHHTDWVNDIILCCNGKTLISASSDT-TVKVWNAHKGF-CMSTLRTHKDYVKALAY 125 Query: 230 NPQNDSVGRTTFASAALDGKAKIWDISLILPIA----TLDCQS-NGLIDLDYFLPGGNE- 391 + V ASA LD + +WD++ + + T+ S +G D Y L Sbjct: 126 AKDKELV-----ASAGLDRQIFLWDVNTLTALTASNNTVTTSSLSGNKDSIYSLAMNQTG 180 Query: 392 QYIITGSLSGNARIWNLRTHKCIRVIKG 475 II+GS R+W+ RT + +KG Sbjct: 181 TVIISGSTEKVLRVWDPRTCAKLMKLKG 208
>GRWD1_HUMAN (Q9BQ67) Glutamate-rich WD repeat-containing protein 1| Length = 446 Score = 45.8 bits (107), Expect = 1e-04 Identities = 42/146 (28%), Positives = 64/146 (43%), Gaps = 8/146 (5%) Frame = +2 Query: 41 LEEVKKFKAHNGWIQALAVHPSLP-LLLSGGCNQGLIKLWDWEKGWTC---LRTFNAHKA 208 ++ + F H G AL P + LL+G C + I LW G + R F H Sbjct: 204 MKPIFSFAGHMGEGFALDWSPRVTGRLLTGDCQKN-IHLWTPTDGGSWHVDQRPFVGHTR 262 Query: 209 KVEALQFNPQNDSVGRTTFASAALDGKAKIWDI----SLILPIATLDCQSNGLIDLDYFL 376 VE LQ++P ++V FAS + D +IWDI S + T D++ Sbjct: 263 SVEDLQWSPTENTV----FASCSADASIRIWDIRAAPSKACMLTTATAHDG---DVNVIS 315 Query: 377 PGGNEQYIITGSLSGNARIWNLRTHK 454 E ++++G G +IW+LR K Sbjct: 316 WSRREPFLLSGGDDGALKIWDLRQFK 341
>WD51B_PONPY (Q5RD06) WD-repeat protein 51B| Length = 451 Score = 45.8 bits (107), Expect = 1e-04 Identities = 36/137 (26%), Positives = 59/137 (43%), Gaps = 1/137 (0%) Frame = +2 Query: 68 HNGWIQALAVHPSLPLLLSGGCNQG-LIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQND 244 H W++ P L++S C++ IK+WD C+ F+ + FNP Sbjct: 143 HTHWVRCAKFSPDGRLIVS--CSEDKTIKIWDTTNK-QCVNNFSDSVGFANFVDFNPSG- 198 Query: 245 SVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGN 424 T ASA D K+WD+ + + S G ++ F P N Y++T S G Sbjct: 199 ----TCIASAGSDQTVKVWDVRVNKLLQHYQVHSGG-VNCISFHPSDN--YLVTASSDGT 251 Query: 425 ARIWNLRTHKCIRVIKG 475 +I +L + I ++G Sbjct: 252 LKILDLLEGRLIYTLQG 268 Score = 32.3 bits (72), Expect = 1.3 Identities = 21/84 (25%), Positives = 39/84 (46%) Frame = +2 Query: 50 VKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQF 229 ++ ++ H+G + ++ HPS L++ + G +K+ D +G + T H V + F Sbjct: 221 LQHYQVHSGGVNCISFHPSDNYLVTAS-SDGTLKILDLLEG-RLIYTLQGHTGPVFTVSF 278 Query: 230 NPQNDSVGRTTFASAALDGKAKIW 301 S G FAS D + +W Sbjct: 279 -----SKGGELFASGGADTQVLLW 297
>GBB1_XENLA (P79959) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) (XGbeta1) Length = 340 Score = 45.8 bits (107), Expect = 1e-04 Identities = 24/88 (27%), Positives = 46/88 (52%) Frame = +2 Query: 44 EEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEAL 223 ++ F H G + +L++ P +SG C+ KLWD +G C +TF H++ + A+ Sbjct: 175 QQTTTFTGHTGDVMSLSLAPDSRCFVSGACDAS-AKLWDVREG-MCRQTFTGHESDINAI 232 Query: 224 QFNPQNDSVGRTTFASAALDGKAKIWDI 307 F P ++ FA+ + D +++D+ Sbjct: 233 CFFPNGNA-----FATGSDDATCRLFDL 255 Score = 37.7 bits (86), Expect = 0.030 Identities = 26/90 (28%), Positives = 41/90 (45%) Frame = +2 Query: 185 RTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDL 364 RT H AK+ A+ + + SA+ DGK IWD + + +S+ ++ Sbjct: 49 RTLRGHLAKIYAMHWGTDS-----RLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTC 103 Query: 365 DYFLPGGNEQYIITGSLSGNARIWNLRTHK 454 Y P GN Y+ G L I+NL+T + Sbjct: 104 AY-APSGN--YVACGGLDNICPIYNLKTRE 130
>WDR48_CHICK (Q5F3K4) WD-repeat protein 48| Length = 678 Score = 45.4 bits (106), Expect = 1e-04 Identities = 38/148 (25%), Positives = 68/148 (45%), Gaps = 6/148 (4%) Frame = +2 Query: 50 VKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQF 229 + + H W+ + + + L+S + +K+W+ KG+ C+ T HK V+AL + Sbjct: 68 IASMEHHTDWVNDIVLCCNGKTLISASSDT-TVKVWNAHKGF-CMSTLRTHKDYVKALAY 125 Query: 230 NPQNDSVGRTTFASAALDGKAKIWDISLILPIA----TLDCQS-NGLIDLDYFLPGGNE- 391 + V ASA LD + +WD++ + + T+ S +G D Y L Sbjct: 126 AKDKELV-----ASAGLDRQIFLWDVNTLTALTASNNTVTTSSLSGNKDSIYSLAMNQMG 180 Query: 392 QYIITGSLSGNARIWNLRTHKCIRVIKG 475 I++GS R+W+ RT + +KG Sbjct: 181 TVIVSGSTEKVLRVWDPRTCAKLMKLKG 208
>WDR48_MACFA (Q4R2Z6) WD-repeat protein 48| Length = 622 Score = 45.4 bits (106), Expect = 1e-04 Identities = 38/148 (25%), Positives = 68/148 (45%), Gaps = 6/148 (4%) Frame = +2 Query: 50 VKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQF 229 + + H W+ + + + L+S + +K+W+ KG+ C+ T HK V+AL + Sbjct: 68 IASMEHHTDWVNDIVLCCNGKTLISASSDT-TVKVWNAHKGF-CMSTLRTHKDYVKALAY 125 Query: 230 NPQNDSVGRTTFASAALDGKAKIWDISLILPIA----TLDCQS-NGLIDLDYFLPGGN-E 391 + V ASA LD + +WD++ + + T+ S +G D Y L Sbjct: 126 AKDKELV-----ASAGLDRQIFLWDVNTLTALTASNNTVTTSSLSGNKDSIYSLAMNQLG 180 Query: 392 QYIITGSLSGNARIWNLRTHKCIRVIKG 475 I++GS R+W+ RT + +KG Sbjct: 181 TIIVSGSTEKVLRVWDPRTCAKLMKLKG 208
>LIS1_RAT (P63004) Platelet-activating factor acetylhydrolase IB alpha| subunit (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1) Length = 409 Score = 45.4 bits (106), Expect = 1e-04 Identities = 33/136 (24%), Positives = 60/136 (44%) Frame = +2 Query: 68 HNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDS 247 H + + HP +++S IK+WD+E G RT H V+ + F D Sbjct: 106 HRSPVTRVIFHPVFSVMVSAS-EDATIKVWDYETG-DFERTLKGHTDSVQDISF----DH 159 Query: 248 VGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNA 427 G+ AS + D K+WD I T+ + + + +P G+ +I++ S Sbjct: 160 SGKL-LASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVA-IMPNGD--HIVSASRDKTI 215 Query: 428 RIWNLRTHKCIRVIKG 475 ++W ++T C++ G Sbjct: 216 KMWEVQTGYCVKTFTG 231 Score = 43.9 bits (102), Expect = 4e-04 Identities = 32/112 (28%), Positives = 49/112 (43%) Frame = +2 Query: 110 PLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGK 289 P LLSG ++ IK+WD G CL T H V + F+ G S A D Sbjct: 308 PFLLSGSRDK-TIKMWDVSTGM-CLMTLVGHDNWVRGVLFHS-----GGKFILSCADDKT 360 Query: 290 AKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNARIWNLR 445 ++WD + TL+ + + LD+ Y++TGS+ ++W R Sbjct: 361 LRVWDYKNKRCMKTLNAHEHFVTSLDFHKTA---PYVVTGSVDQTVKVWECR 409 Score = 38.1 bits (87), Expect = 0.023 Identities = 21/79 (26%), Positives = 41/79 (51%) Frame = +2 Query: 68 HNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDS 247 H+ W++ + H +LS ++ L ++WD+ K C++T NAH+ V +L F+ Sbjct: 336 HDNWVRGVLFHSGGKFILSCADDKTL-RVWDY-KNKRCMKTLNAHEHFVTSLDFHKTAPY 393 Query: 248 VGRTTFASAALDGKAKIWD 304 V + ++D K+W+ Sbjct: 394 V-----VTGSVDQTVKVWE 407
>LIS1_PANTR (Q5IS43) Platelet-activating factor acetylhydrolase IB alpha| subunit (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1) Length = 409 Score = 45.4 bits (106), Expect = 1e-04 Identities = 33/136 (24%), Positives = 60/136 (44%) Frame = +2 Query: 68 HNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDS 247 H + + HP +++S IK+WD+E G RT H V+ + F D Sbjct: 106 HRSPVTRVIFHPVFSVMVSAS-EDATIKVWDYETG-DFERTLKGHTDSVQDISF----DH 159 Query: 248 VGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNA 427 G+ AS + D K+WD I T+ + + + +P G+ +I++ S Sbjct: 160 SGKL-LASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVA-IMPNGD--HIVSASRDKTI 215 Query: 428 RIWNLRTHKCIRVIKG 475 ++W ++T C++ G Sbjct: 216 KMWEVQTGYCVKTFTG 231 Score = 41.6 bits (96), Expect = 0.002 Identities = 31/112 (27%), Positives = 48/112 (42%) Frame = +2 Query: 110 PLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGK 289 P LLSG ++ IK+WD G CL T H V + F+ G S A D Sbjct: 308 PFLLSGSRDK-TIKMWDVSTGM-CLMTLVGHDNWVRGVLFHS-----GGKFILSCADDKT 360 Query: 290 AKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNARIWNLR 445 ++WD + TL+ + + LD+ Y++TG + ++W R Sbjct: 361 LRVWDYKNKRCMKTLNAHEHFVTSLDFHKTA---PYVVTGFVDQTVKVWECR 409 Score = 37.0 bits (84), Expect = 0.052 Identities = 21/79 (26%), Positives = 40/79 (50%) Frame = +2 Query: 68 HNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDS 247 H+ W++ + H +LS ++ L ++WD+ K C++T NAH+ V +L F+ Sbjct: 336 HDNWVRGVLFHSGGKFILSCADDKTL-RVWDY-KNKRCMKTLNAHEHFVTSLDFHKTAPY 393 Query: 248 VGRTTFASAALDGKAKIWD 304 V + +D K+W+ Sbjct: 394 V-----VTGFVDQTVKVWE 407
>LIS1_MOUSE (P63005) Platelet-activating factor acetylhydrolase IB alpha| subunit (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1) Length = 409 Score = 45.4 bits (106), Expect = 1e-04 Identities = 33/136 (24%), Positives = 60/136 (44%) Frame = +2 Query: 68 HNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDS 247 H + + HP +++S IK+WD+E G RT H V+ + F D Sbjct: 106 HRSPVTRVIFHPVFSVMVSAS-EDATIKVWDYETG-DFERTLKGHTDSVQDISF----DH 159 Query: 248 VGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNA 427 G+ AS + D K+WD I T+ + + + +P G+ +I++ S Sbjct: 160 SGKL-LASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVA-IMPNGD--HIVSASRDKTI 215 Query: 428 RIWNLRTHKCIRVIKG 475 ++W ++T C++ G Sbjct: 216 KMWEVQTGYCVKTFTG 231 Score = 43.9 bits (102), Expect = 4e-04 Identities = 32/112 (28%), Positives = 49/112 (43%) Frame = +2 Query: 110 PLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGK 289 P LLSG ++ IK+WD G CL T H V + F+ G S A D Sbjct: 308 PFLLSGSRDK-TIKMWDVSTGM-CLMTLVGHDNWVRGVLFHS-----GGKFILSCADDKT 360 Query: 290 AKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNARIWNLR 445 ++WD + TL+ + + LD+ Y++TGS+ ++W R Sbjct: 361 LRVWDYKNKRCMKTLNAHEHFVTSLDFHKTA---PYVVTGSVDQTVKVWECR 409 Score = 38.1 bits (87), Expect = 0.023 Identities = 21/79 (26%), Positives = 41/79 (51%) Frame = +2 Query: 68 HNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDS 247 H+ W++ + H +LS ++ L ++WD+ K C++T NAH+ V +L F+ Sbjct: 336 HDNWVRGVLFHSGGKFILSCADDKTL-RVWDY-KNKRCMKTLNAHEHFVTSLDFHKTAPY 393 Query: 248 VGRTTFASAALDGKAKIWD 304 V + ++D K+W+ Sbjct: 394 V-----VTGSVDQTVKVWE 407
>LIS1_HUMAN (P43034) Platelet-activating factor acetylhydrolase IB alpha| subunit (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1) Length = 409 Score = 45.4 bits (106), Expect = 1e-04 Identities = 33/136 (24%), Positives = 60/136 (44%) Frame = +2 Query: 68 HNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDS 247 H + + HP +++S IK+WD+E G RT H V+ + F D Sbjct: 106 HRSPVTRVIFHPVFSVMVSAS-EDATIKVWDYETG-DFERTLKGHTDSVQDISF----DH 159 Query: 248 VGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNA 427 G+ AS + D K+WD I T+ + + + +P G+ +I++ S Sbjct: 160 SGKL-LASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVA-IMPNGD--HIVSASRDKTI 215 Query: 428 RIWNLRTHKCIRVIKG 475 ++W ++T C++ G Sbjct: 216 KMWEVQTGYCVKTFTG 231 Score = 43.9 bits (102), Expect = 4e-04 Identities = 32/112 (28%), Positives = 49/112 (43%) Frame = +2 Query: 110 PLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGK 289 P LLSG ++ IK+WD G CL T H V + F+ G S A D Sbjct: 308 PFLLSGSRDK-TIKMWDVSTGM-CLMTLVGHDNWVRGVLFHS-----GGKFILSCADDKT 360 Query: 290 AKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNARIWNLR 445 ++WD + TL+ + + LD+ Y++TGS+ ++W R Sbjct: 361 LRVWDYKNKRCMKTLNAHEHFVTSLDFHKTA---PYVVTGSVDQTVKVWECR 409 Score = 38.1 bits (87), Expect = 0.023 Identities = 21/79 (26%), Positives = 41/79 (51%) Frame = +2 Query: 68 HNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDS 247 H+ W++ + H +LS ++ L ++WD+ K C++T NAH+ V +L F+ Sbjct: 336 HDNWVRGVLFHSGGKFILSCADDKTL-RVWDY-KNKRCMKTLNAHEHFVTSLDFHKTAPY 393 Query: 248 VGRTTFASAALDGKAKIWD 304 V + ++D K+W+ Sbjct: 394 V-----VTGSVDQTVKVWE 407
>RBBP7_PONPY (Q5R654) Histone-binding protein RBBP7 (Retinoblastoma-binding| protein 7) (RBBP-7) Length = 426 Score = 45.4 bits (106), Expect = 1e-04 Identities = 32/121 (26%), Positives = 57/121 (47%), Gaps = 1/121 (0%) Frame = +2 Query: 65 AHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKV-EALQFNPQN 241 AH + L+ +P +L+ G + LWD L TF +HK ++ + + ++P N Sbjct: 270 AHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHTFESHKDEIFQVVHWSPHN 329 Query: 242 DSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSG 421 + T AS+ D + +WD+S I + + +G +L F+ GG+ I S + Sbjct: 330 E----TILASSGTDRRLNVWDLSKIGEEQSAEDAEDGPPEL-LFIHGGHTAKISDFSWNP 384 Query: 422 N 424 N Sbjct: 385 N 385 Score = 40.0 bits (92), Expect = 0.006 Identities = 28/131 (21%), Positives = 57/131 (43%), Gaps = 3/131 (2%) Frame = +2 Query: 59 FKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTF--NAHKAKVEALQFN 232 F H+ ++ +A H L + + +WD T + +AH A+V L FN Sbjct: 222 FTGHSAVVEDVAWHLLHESLFGSVADDQKLMMWDTRSNTTSKPSHLVDAHTAEVNCLSFN 281 Query: 233 PQNDSVGRTTFASAALDGKAKIWDI-SLILPIATLDCQSNGLIDLDYFLPGGNEQYIITG 409 P ++ + A+ + D +WD+ +L L + T + + + + ++ P NE + + Sbjct: 282 PYSEFI----LATGSADKTVALWDLRNLKLKLHTFESHKDEIFQVVHWSP-HNETILASS 336 Query: 410 SLSGNARIWNL 442 +W+L Sbjct: 337 GTDRRLNVWDL 347
>WDR48_PONPY (Q5RAW8) WD-repeat protein 48| Length = 677 Score = 45.4 bits (106), Expect = 1e-04 Identities = 38/148 (25%), Positives = 68/148 (45%), Gaps = 6/148 (4%) Frame = +2 Query: 50 VKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQF 229 + + H W+ + + + L+S + +K+W+ KG+ C+ T HK V+AL + Sbjct: 68 IASMEHHTDWVNDIVLCCNGKTLISASSDT-TVKVWNAHKGF-CMSTLRTHKDYVKALAY 125 Query: 230 NPQNDSVGRTTFASAALDGKAKIWDISLILPIA----TLDCQS-NGLIDLDYFLPGGN-E 391 + V ASA LD + +WD++ + + T+ S +G D Y L Sbjct: 126 AKDKELV-----ASAGLDRQIFLWDVNTLTALTASNNTVTTSSLSGNKDSIYSLAMNQLG 180 Query: 392 QYIITGSLSGNARIWNLRTHKCIRVIKG 475 I++GS R+W+ RT + +KG Sbjct: 181 TIIVSGSTEKVLRVWDPRTCAKLMKLKG 208
>WDR48_HUMAN (Q8TAF3) WD-repeat protein 48 (WD repeat endosomal protein) (p80)| Length = 677 Score = 45.4 bits (106), Expect = 1e-04 Identities = 38/148 (25%), Positives = 68/148 (45%), Gaps = 6/148 (4%) Frame = +2 Query: 50 VKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQF 229 + + H W+ + + + L+S + +K+W+ KG+ C+ T HK V+AL + Sbjct: 68 IASMEHHTDWVNDIVLCCNGKTLISASSDT-TVKVWNAHKGF-CMSTLRTHKDYVKALAY 125 Query: 230 NPQNDSVGRTTFASAALDGKAKIWDISLILPIA----TLDCQS-NGLIDLDYFLPGGN-E 391 + V ASA LD + +WD++ + + T+ S +G D Y L Sbjct: 126 AKDKELV-----ASAGLDRQIFLWDVNTLTALTASNNTVTTSSLSGNKDSIYSLAMNQLG 180 Query: 392 QYIITGSLSGNARIWNLRTHKCIRVIKG 475 I++GS R+W+ RT + +KG Sbjct: 181 TIIVSGSTEKVLRVWDPRTCAKLMKLKG 208
>TAF5_SCHPO (O13282) Transcription initiation factor TFIID subunit 5| (Transcription initiation factor TFIID 72 kDa subunit) (TAFII-72) Length = 643 Score = 45.1 bits (105), Expect = 2e-04 Identities = 36/138 (26%), Positives = 58/138 (42%), Gaps = 1/138 (0%) Frame = +2 Query: 65 AHNGWIQALAVHPSLPLLLSGGCNQGL-IKLWDWEKGWTCLRTFNAHKAKVEALQFNPQN 241 +H+G + P LLS C++ +LW + T L + H V + F P Sbjct: 377 SHSGPVYGTTFSPDNKYLLS--CSEDASARLWSVDTK-TALVAYKGHTGPVWDVAFGPFG 433 Query: 242 DSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSG 421 FA+A+ D A++W I P+ + L D+D N Y++TGS Sbjct: 434 HY-----FATASHDQTAQLWSCDHIYPLRVF---AGHLSDVDCVTFHPNSAYVLTGSSDK 485 Query: 422 NARIWNLRTHKCIRVIKG 475 R+W++ +RV G Sbjct: 486 TCRLWDVHRGHSVRVFNG 503 Score = 44.3 bits (103), Expect = 3e-04 Identities = 31/131 (23%), Positives = 55/131 (41%) Frame = +2 Query: 50 VKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQF 229 ++ F H + + HP+ +L+G ++ +LWD +G + +R FN H V A+ Sbjct: 456 LRVFAGHLSDVDCVTFHPNSAYVLTGSSDK-TCRLWDVHRGHS-VRVFNGHTQPVTAVAI 513 Query: 230 NPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITG 409 P T ASA +G +WDI I T+ + L + +++G Sbjct: 514 APDGH-----TMASADSEGLIHLWDIGTGRRIKTMRGHRGNIYSLSF---SRESTVLVSG 565 Query: 410 SLSGNARIWNL 442 R W++ Sbjct: 566 GSDCTVRAWDV 576
>PRP19_CAEEL (Q10051) PRP19/PSO4 homolog| Length = 492 Score = 45.1 bits (105), Expect = 2e-04 Identities = 45/180 (25%), Positives = 80/180 (44%), Gaps = 7/180 (3%) Frame = +2 Query: 14 PPAXCKTLGLEEVKKFKAHNG-------WIQALAVHPSLPLLLSGGCNQGLIKLWDWEKG 172 P KT L E+K+ +H G I AL + +L L +GG ++ ++ L+D+EK Sbjct: 185 PEGLAKTEELAELKQTASHTGIHSTGTPGITALDIKGNLSL--TGGIDKTVV-LYDYEKE 241 Query: 173 WTCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNG 352 ++TF H K+ A+ +P N T SA+ D ++W + A +D Sbjct: 242 QV-MQTFKGHNKKINAVVLHPDN-----ITAISASADSHIRVWSATDSSSKAIIDVHQAP 295 Query: 353 LIDLDYFLPGGNEQYIITGSLSGNARIWNLRTHKCIRVIKGTSITSGAGCSVRVVYCSPD 532 + D+ G YI++ S ++R+ K + + S+ G+ +V + PD Sbjct: 296 VTDISLNASG---DYILSASDDSYWAFSDIRSGKSLCKV---SVEPGSQIAVHSIEFHPD 349 Score = 34.3 bits (77), Expect = 0.34 Identities = 21/84 (25%), Positives = 37/84 (44%) Frame = +2 Query: 212 VEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNE 391 V +++F+P F + A D KIWD+ A + + + + N Sbjct: 341 VHSIEFHPDG-----LIFGTGAADAVVKIWDLKNQTVAAAFPGHTAAVRSIAF---SENG 392 Query: 392 QYIITGSLSGNARIWNLRTHKCIR 463 Y+ TGS G ++W+LR K ++ Sbjct: 393 YYLATGSEDGEVKLWDLRKLKNLK 416
>WSB1_MOUSE (O54927) WD repeat and SOCS box-containing protein 1 (WSB-1)| Length = 421 Score = 45.1 bits (105), Expect = 2e-04 Identities = 25/85 (29%), Positives = 41/85 (48%) Frame = +2 Query: 50 VKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQF 229 VK +AH W+ + A P +L S G ++ + LW+ +K +T +R H V A F Sbjct: 207 VKVLRAHQNWVYSCAFSPDCSMLCSVGASKAVF-LWNMDK-YTMIRKLEGHHHDVVACDF 264 Query: 230 NPQNDSVGRTTFASAALDGKAKIWD 304 +P A+A+ D + +WD Sbjct: 265 SPDG-----ALLATASYDTRVYVWD 284 Score = 35.4 bits (80), Expect = 0.15 Identities = 23/65 (35%), Positives = 30/65 (46%) Frame = +2 Query: 113 LLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKA 292 LLL+ G N G IK+WD G L + H V L F P G SA+ D Sbjct: 141 LLLATGLNNGRIKIWDVYTGKLLLNLVD-HIEMVRDLTFAPD----GSLLLVSASRDKTL 195 Query: 293 KIWDI 307 ++WD+ Sbjct: 196 RVWDL 200
>WDR48_MOUSE (Q8BH57) WD-repeat protein 48| Length = 676 Score = 45.1 bits (105), Expect = 2e-04 Identities = 38/148 (25%), Positives = 68/148 (45%), Gaps = 6/148 (4%) Frame = +2 Query: 50 VKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQF 229 + + H W+ + + + L+S + +K+W+ KG+ C+ T HK V+AL + Sbjct: 68 IASMEHHTDWVNDVVLCCNGKTLISASSDT-TVKVWNAHKGF-CMSTLRTHKDYVKALAY 125 Query: 230 NPQNDSVGRTTFASAALDGKAKIWDISLILPIA----TLDCQS-NGLIDLDYFLPGGN-E 391 + V ASA LD + +WD++ + + T+ S +G D Y L Sbjct: 126 AKDKELV-----ASAGLDRQIFLWDVNTLTALTASNNTVTTSSLSGNKDSIYSLAMNQLG 180 Query: 392 QYIITGSLSGNARIWNLRTHKCIRVIKG 475 I++GS R+W+ RT + +KG Sbjct: 181 TIIVSGSTEKVLRVWDPRTCAKLMKLKG 208
>YK16_YEAST (P36130) Hypothetical 74.7 kDa Trp-Asp repeats-containing protein| in DAL80-GAP1 intergenic region Length = 659 Score = 45.1 bits (105), Expect = 2e-04 Identities = 20/71 (28%), Positives = 40/71 (56%) Frame = +2 Query: 257 TTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNARIW 436 + A+ DG ++WD+ + P+ L+ ++G+ L + + + ++TGS+ + RIW Sbjct: 516 SALATGTKDGIVRLWDLRVGKPVRLLEGHTDGITSLKF-----DSEKLVTGSMDNSVRIW 570 Query: 437 NLRTHKCIRVI 469 +LRT + VI Sbjct: 571 DLRTSSILDVI 581 Score = 36.6 bits (83), Expect = 0.068 Identities = 48/215 (22%), Positives = 80/215 (37%), Gaps = 40/215 (18%) Frame = +2 Query: 47 EVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDW------------------EKG 172 +V + H + + + +L G +KLWD E Sbjct: 370 QVGELPGHLATVNCMQIDKKNYNMLITGSKDATLKLWDLNLSREIYLDHSPLKEKTEEIV 429 Query: 173 WTCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDC---- 340 C+ F HK ++ AL F+ + S + D K WD++ I LD Sbjct: 430 TPCIHNFELHKDEITALSFDSE-------ALVSGSRDKKIFHWDLTTGKCIQQLDLIFTP 482 Query: 341 -----------QSNG--LIDLDYFLPGGNEQY---IITGSLSGNARIWNLRTHKCIRVIK 472 +NG L+ + + G + Y + TG+ G R+W+LR K +R+++ Sbjct: 483 THSDIKMPARSLNNGACLLGTEAPMIGALQCYNSALATGTKDGIVRLWDLRVGKPVRLLE 542 Query: 473 G--TSITSGAGCSVRVVYCSPDPPLLIRTFEDDSL 571 G ITS S ++V S D + I S+ Sbjct: 543 GHTDGITSLKFDSEKLVTGSMDNSVRIWDLRTSSI 577
>YAGE_SCHPO (Q9UTN4) Hypothetical WD-repeat protein C12G12.14c in chromosome I| Length = 509 Score = 44.7 bits (104), Expect = 2e-04 Identities = 36/145 (24%), Positives = 64/145 (44%) Frame = +2 Query: 41 LEEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEA 220 L VK +AH ++ +A P+ ++ + G +K+W++ L+ H V+ Sbjct: 154 LNNVKIVQAHEMEVRDVAFSPNDSKFVTAS-DDGSLKVWNFHMSTEELK-LTGHGWDVKT 211 Query: 221 LQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYI 400 + ++P + AS + D K WD IATL N ++ F Y+ Sbjct: 212 VDWHPS-----KGLLASGSKDNLVKFWDPRTGTCIATLHGHKNTIMQAS-FQKNFGSNYL 265 Query: 401 ITGSLSGNARIWNLRTHKCIRVIKG 475 T S R+++LR K +RV++G Sbjct: 266 ATVSRDSTCRVFDLRAMKDVRVLRG 290 Score = 36.6 bits (83), Expect = 0.068 Identities = 30/119 (25%), Positives = 52/119 (43%) Frame = +2 Query: 119 LSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKI 298 L G G++K + E ++ AH+ +V + F+P NDS F +A+ DG K+ Sbjct: 138 LISGDGGGMVKYF--EPNLNNVKIVQAHEMEVRDVAFSP-NDS----KFVTASDDGSLKV 190 Query: 299 WDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNARIWNLRTHKCIRVIKG 475 W+ + L + +D+ G + +GS + W+ RT CI + G Sbjct: 191 WNFHMSTEELKLTGHGWDVKTVDWHPSKG---LLASGSKDNLVKFWDPRTGTCIATLHG 246
>TRCB_XENLA (Q91854) Beta-TrCP (Beta-transducin repeat-containing protein)| Length = 518 Score = 44.7 bits (104), Expect = 2e-04 Identities = 28/112 (25%), Positives = 50/112 (44%), Gaps = 2/112 (1%) Frame = +2 Query: 146 IKLWDWEKGW--TCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLIL 319 I +WD T R H+A V + F+ + SA+ D K+W+ S Sbjct: 334 IAVWDMASATDITLRRVLVGHRAAVNVVDFDDKY-------IVSASGDRTIKVWNTSTCE 386 Query: 320 PIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNARIWNLRTHKCIRVIKG 475 + TL+ G+ L Y ++ +++GS R+W++ C+RV++G Sbjct: 387 FVRTLNGHKRGIACLQY-----RDRLVVSGSSDNTIRLWDIECGACLRVLEG 433 Score = 43.1 bits (100), Expect = 7e-04 Identities = 28/89 (31%), Positives = 41/89 (46%) Frame = +2 Query: 71 NGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDSV 250 NG + +A L+ G + I+LWD E G CLR H+ V ++F+ + Sbjct: 392 NGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECG-ACLRVLEGHEELVRCIRFDNKR--- 447 Query: 251 GRTTFASAALDGKAKIWDISLILPIATLD 337 S A DGK K+WD+ +A LD Sbjct: 448 ----IVSGAYDGKIKVWDL-----VAALD 467 Score = 31.6 bits (70), Expect = 2.2 Identities = 22/86 (25%), Positives = 37/86 (43%) Frame = +2 Query: 212 VEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNE 391 V LQ++ Q S D KIWD + + L + ++ L Y +E Sbjct: 235 VYCLQYDDQK-------IVSGLRDNTIKIWDKNTLECKRVLMGHTGSVLCLQY-----DE 282 Query: 392 QYIITGSLSGNARIWNLRTHKCIRVI 469 + IITGS R+W++ T + + + Sbjct: 283 RVIITGSSDSTVRVWDVNTGEMLNTL 308
>WDR17_HUMAN (Q8IZU2) WD-repeat protein 17| Length = 1322 Score = 44.7 bits (104), Expect = 2e-04 Identities = 42/148 (28%), Positives = 65/148 (43%), Gaps = 8/148 (5%) Frame = +2 Query: 140 GLIKLWDW-EKGWTCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLI 316 G + L+D K W LR H + +F P + ++ A+A+ DG K+WDI+ + Sbjct: 372 GGVGLYDMGAKKWDFLRDLG-HVETIFDCKFKPDDPNL----LATASFDGTIKVWDINTL 426 Query: 317 LPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNARIWNLRTHKCIRVIKGTSITSGA 496 + T + L + PGG I G+ A IWN++ K I+ T+G Sbjct: 427 TAVYTSPGNEGVIYSLSW-APGG-LNCIAGGTSRNGAFIWNVQKGKIIQRFNEHG-TNGI 483 Query: 497 GC-------SVRVVYCSPDPPLLIRTFE 559 C S R+ CS D +IRT + Sbjct: 484 FCIAWSHKDSKRIATCSSDGFCIIRTID 511
>PWP2_NEUCR (Q9C270) Periodic tryptophan protein 2 homolog| Length = 899 Score = 44.3 bits (103), Expect = 3e-04 Identities = 30/128 (23%), Positives = 55/128 (42%) Frame = +2 Query: 80 IQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRT 259 I + ++ S L G G + +W+W+ L+ H + +L ++P + Sbjct: 299 IDFVTINKSGEWLAFGASKLGQLLVWEWQSESYILKQ-QGHFDSMNSLVYSPDGQRI--- 354 Query: 260 TFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNARIWN 439 + A DGK K+WD I T ++G+ ++ G + T SL G+ R W+ Sbjct: 355 --VTVADDGKIKVWDTESGFCIVTFTEHTSGITACEFSKKG---NVLFTSSLDGSIRAWD 409 Query: 440 LRTHKCIR 463 L ++ R Sbjct: 410 LIRYRNFR 417
>A16L1_PONPY (Q5RAC9) Autophagy-related protein 16-1 (APG16-like 1)| Length = 607 Score = 44.3 bits (103), Expect = 3e-04 Identities = 40/155 (25%), Positives = 71/155 (45%), Gaps = 2/155 (1%) Frame = +2 Query: 59 FKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTC--LRTFNAHKAKVEALQFN 232 F AH+G + A+ P LL +GG ++ +KLW+ G C + + A + +++F Sbjct: 318 FDAHDGEVNAVQFSPGSRLLATGGMDRR-VKLWE-VFGEKCEFKGSLSGSNAGITSIEF- 374 Query: 233 PQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGS 412 DS G A A+ D ++IW + TL S ++ + L I++GS Sbjct: 375 ---DSAGSYLLA-ASNDFASRIWTVDDSRLRHTLTGHSGKVLSAKFLLDNAR---IVSGS 427 Query: 413 LSGNARIWNLRTHKCIRVIKGTSITSGAGCSVRVV 517 + W+LR+ CI+ + S + C+ + V Sbjct: 428 HDRTLKHWDLRSKVCIKTVFAGSSCNDIVCTEQCV 462 Score = 36.6 bits (83), Expect = 0.068 Identities = 25/104 (24%), Positives = 47/104 (45%), Gaps = 2/104 (1%) Frame = +2 Query: 176 TCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDI--SLILPIATLDCQSN 349 T L F+AH +V A+QF+P G A+ +D + K+W++ +L + Sbjct: 313 TALCVFDAHDGEVNAVQFSP-----GSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNA 367 Query: 350 GLIDLDYFLPGGNEQYIITGSLSGNARIWNLRTHKCIRVIKGTS 481 G+ +++ G Y++ S +RIW + + + G S Sbjct: 368 GITSIEFDSAG---SYLLAASNDFASRIWTVDDSRLRHTLTGHS 408
>FBW1B_HUMAN (Q9UKB1) F-box/WD-repeat protein 11 (F-box/WD-repeat protein 1B)| (F-box and WD-repeats protein beta-TrCP2) Length = 542 Score = 44.3 bits (103), Expect = 3e-04 Identities = 28/112 (25%), Positives = 49/112 (43%), Gaps = 2/112 (1%) Frame = +2 Query: 146 IKLWDWEKGW--TCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLIL 319 I +WD T R H+A V + F+ + SA+ D K+W S Sbjct: 342 IAVWDMASATDITLRRVLVGHRAAVNVVDFDDKY-------IVSASGDRTIKVWSTSTCE 394 Query: 320 PIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNARIWNLRTHKCIRVIKG 475 + TL+ G+ L Y ++ +++GS R+W++ C+RV++G Sbjct: 395 FVRTLNGHKRGIACLQY-----RDRLVVSGSSDNTIRLWDIECGACLRVLEG 441 Score = 43.9 bits (102), Expect = 4e-04 Identities = 29/92 (31%), Positives = 42/92 (45%), Gaps = 4/92 (4%) Frame = +2 Query: 71 NGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDSV 250 NG + +A L+ G + I+LWD E G CLR H+ V ++F+ + Sbjct: 400 NGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECG-ACLRVLEGHEELVRCIRFDNKR--- 455 Query: 251 GRTTFASAALDGKAKIWDISLIL----PIATL 334 S A DGK K+WD+ L P +TL Sbjct: 456 ----IVSGAYDGKIKVWDLQAALDPRAPASTL 483 Score = 33.5 bits (75), Expect = 0.57 Identities = 17/67 (25%), Positives = 32/67 (47%) Frame = +2 Query: 269 SAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNARIWNLRT 448 S D KIWD + + + L + ++ L Y +E+ I+TGS R+W++ T Sbjct: 255 SGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQY-----DERVIVTGSSDSTVRVWDVNT 309 Query: 449 HKCIRVI 469 + + + Sbjct: 310 GEVLNTL 316 Score = 30.0 bits (66), Expect = 6.3 Identities = 23/81 (28%), Positives = 32/81 (39%), Gaps = 8/81 (9%) Frame = +2 Query: 128 GCNQGLIKLWDWEKGWT--------CLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALD 283 G G IK+WD + CLRT H +V LQF+ S++ D Sbjct: 459 GAYDGKIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRLQFD-------EFQIISSSHD 511 Query: 284 GKAKIWDISLILPIATLDCQS 346 IWD + P A + +S Sbjct: 512 DTILIWDFLNVPPSAQNETRS 532
>HAT2_USTMA (Q4P553) Histone acetyltransferase type B subunit 2 (EC 2.3.1.48)| Length = 485 Score = 44.3 bits (103), Expect = 3e-04 Identities = 30/111 (27%), Positives = 54/111 (48%) Frame = +2 Query: 56 KFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNP 235 + +AH G + ALA P +L G + + +WD L + +H ++ ++ ++P Sbjct: 331 RVEAHTGEVNALAFSPENENILVTGSSDKSVGVWDLRNLKVKLHSLESHTDEILSVCWSP 390 Query: 236 QNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGN 388 + T ASA+ D + +WD+S I T D +G +L F+ GG+ Sbjct: 391 HH----ATVLASASADRRVNLWDLSKIGQEQTPDDAEDGPPEL-IFVHGGH 436 Score = 32.7 bits (73), Expect = 0.98 Identities = 25/90 (27%), Positives = 43/90 (47%), Gaps = 1/90 (1%) Frame = +2 Query: 188 TFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSN-GLIDL 364 T+ H A VE + ++ ++S+ F S D + IWDI +++ G ++ Sbjct: 286 TYTGHTAIVEDVAWHNHHESL----FGSVGDDRQLLIWDIREPASAPKYRVEAHTGEVNA 341 Query: 365 DYFLPGGNEQYIITGSLSGNARIWNLRTHK 454 F P NE ++TGS + +W+LR K Sbjct: 342 LAFSPE-NENILVTGSSDKSVGVWDLRNLK 370
>GBB4_RAT (O35353) Guanine nucleotide-binding protein beta subunit 4| (Transducin beta chain 4) Length = 339 Score = 44.3 bits (103), Expect = 3e-04 Identities = 24/88 (27%), Positives = 44/88 (50%) Frame = +2 Query: 44 EEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEAL 223 ++ F H+G + +L++ P L +SG C+ KLWD G C ++F H + + A+ Sbjct: 174 QQTTTFTGHSGDVMSLSLSPDLKTFVSGACDAS-SKLWDIRDG-MCRQSFTGHISDINAV 231 Query: 224 QFNPQNDSVGRTTFASAALDGKAKIWDI 307 F P FA+ + D +++D+ Sbjct: 232 SFFPSG-----YAFATGSDDATCRLFDL 254 Score = 36.6 bits (83), Expect = 0.068 Identities = 26/90 (28%), Positives = 41/90 (45%) Frame = +2 Query: 185 RTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDL 364 RT H AK+ A+ + + SA+ DGK IWD + + +S+ ++ Sbjct: 48 RTLRGHLAKIYAMHWGYDS-----RLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTC 102 Query: 365 DYFLPGGNEQYIITGSLSGNARIWNLRTHK 454 Y P GN Y+ G L I+NL+T + Sbjct: 103 AY-APSGN--YVACGGLDNICSIYNLKTRE 129
>GBB4_MOUSE (P29387) Guanine nucleotide-binding protein beta subunit 4| (Transducin beta chain 4) Length = 339 Score = 44.3 bits (103), Expect = 3e-04 Identities = 24/88 (27%), Positives = 44/88 (50%) Frame = +2 Query: 44 EEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEAL 223 ++ F H+G + +L++ P L +SG C+ KLWD G C ++F H + + A+ Sbjct: 174 QQTTTFTGHSGDVMSLSLSPDLKTFVSGACDAS-SKLWDIRDG-MCRQSFTGHISDINAV 231 Query: 224 QFNPQNDSVGRTTFASAALDGKAKIWDI 307 F P FA+ + D +++D+ Sbjct: 232 SFFPSG-----YAFATGSDDATCRLFDL 254 Score = 36.6 bits (83), Expect = 0.068 Identities = 26/90 (28%), Positives = 41/90 (45%) Frame = +2 Query: 185 RTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDL 364 RT H AK+ A+ + + SA+ DGK IWD + + +S+ ++ Sbjct: 48 RTLRGHLAKIYAMHWGYDS-----RLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTC 102 Query: 365 DYFLPGGNEQYIITGSLSGNARIWNLRTHK 454 Y P GN Y+ G L I+NL+T + Sbjct: 103 AY-APSGN--YVACGGLDNICSIYNLKTRE 129
>SWD3_SCHPO (O43017) Set1 complex component swd3 (Set1C component swd3)| (COMPASS component swd3) (Complex proteins associated with set1 protein swd3) Length = 380 Score = 44.3 bits (103), Expect = 3e-04 Identities = 29/117 (24%), Positives = 52/117 (44%) Frame = +2 Query: 119 LSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKI 298 L+ + I++WD+EK + +R H V ++ FNP T S + D +I Sbjct: 111 LASASDDKTIRIWDFEKRCS-VRCLKGHTNYVSSIDFNPLG-----TLLVSGSWDETVRI 164 Query: 299 WDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNARIWNLRTHKCIRVI 469 W++ + L S +I + G T S G ARIW++ + +C++ + Sbjct: 165 WNLQDGTCLRMLPAHSEPIISVSISADG---TLCATASYDGMARIWDVLSGQCLKTL 218 Score = 39.3 bits (90), Expect = 0.010 Identities = 35/148 (23%), Positives = 62/148 (41%) Frame = +2 Query: 38 GLEEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVE 217 G E H + ++V P+ + + + G IK+W + T H + Sbjct: 43 GFSEYCTLFGHEKSVTCVSVSPNKRWIATSS-SDGTIKIWS-ALTFRLECTLFGHYRGIS 100 Query: 218 ALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQY 397 +++ + G ASA+ D +IWD + L +N + +D F P G Sbjct: 101 QVKW-----ATGSKYLASASDDKTIRIWDFEKRCSVRCLKGHTNYVSSID-FNPLGT--L 152 Query: 398 IITGSLSGNARIWNLRTHKCIRVIKGTS 481 +++GS RIWNL+ C+R++ S Sbjct: 153 LVSGSWDETVRIWNLQDGTCLRMLPAHS 180
>LIS1_MACFA (Q8HXX0) Platelet-activating factor acetylhydrolase IB alpha| subunit (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1) Length = 409 Score = 43.9 bits (102), Expect = 4e-04 Identities = 32/112 (28%), Positives = 49/112 (43%) Frame = +2 Query: 110 PLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGK 289 P LLSG ++ IK+WD G CL T H V + F+ G S A D Sbjct: 308 PFLLSGSRDK-TIKMWDVSTGM-CLMTLVGHDNWVRGVLFHS-----GGKFILSCADDKT 360 Query: 290 AKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNARIWNLR 445 ++WD + TL+ + + LD+ Y++TGS+ ++W R Sbjct: 361 LRVWDYKNKRCMKTLNAHEHFVTSLDFHKTA---PYVVTGSVDQTVKVWECR 409 Score = 43.1 bits (100), Expect = 7e-04 Identities = 31/136 (22%), Positives = 59/136 (43%) Frame = +2 Query: 68 HNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDS 247 H + + HP +++S IK+WD+E G RT H V+ + F D Sbjct: 106 HRSPVTRVIFHPVFSVMVSAS-EDATIKVWDYETG-DFERTLKGHTDSVQDISF----DH 159 Query: 248 VGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNA 427 G+ S + D K+WD I T+ + + + +P G+ ++++ S Sbjct: 160 SGKL-LTSCSADMTIKLWDFQGFECIRTMHGHDHNVSSVA-IMPNGD--HLVSASRDKTI 215 Query: 428 RIWNLRTHKCIRVIKG 475 ++W ++T C++ G Sbjct: 216 KMWEVQTGYCVKTFTG 231 Score = 38.1 bits (87), Expect = 0.023 Identities = 21/79 (26%), Positives = 41/79 (51%) Frame = +2 Query: 68 HNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDS 247 H+ W++ + H +LS ++ L ++WD+ K C++T NAH+ V +L F+ Sbjct: 336 HDNWVRGVLFHSGGKFILSCADDKTL-RVWDY-KNKRCMKTLNAHEHFVTSLDFHKTAPY 393 Query: 248 VGRTTFASAALDGKAKIWD 304 V + ++D K+W+ Sbjct: 394 V-----VTGSVDQTVKVWE 407
>KI21B_HUMAN (O75037) Kinesin family member 21B| Length = 1637 Score = 43.9 bits (102), Expect = 4e-04 Identities = 38/127 (29%), Positives = 54/127 (42%), Gaps = 3/127 (2%) Frame = +2 Query: 68 HNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDS 247 H I+ LA+ + L SG + G IK WD ++ + NAHK V AL F P Sbjct: 1503 HYDGIECLAIQGDI--LFSGSRDNG-IKKWDLDQQELIQQIPNAHKDWVCALAFIP---- 1555 Query: 248 VGRTTFASAALDGKAKIWDISLILPIATL---DCQSNGLIDLDYFLPGGNEQYIITGSLS 418 GR SA G K+W++ PI + D N + N ++I T S Sbjct: 1556 -GRPMLLSACRAGVIKVWNVDNFTPIGEIKGHDSPINAICT--------NAKHIFTASSD 1606 Query: 419 GNARIWN 439 ++WN Sbjct: 1607 CRVKLWN 1613 Score = 41.6 bits (96), Expect = 0.002 Identities = 24/80 (30%), Positives = 42/80 (52%) Frame = +2 Query: 65 AHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQND 244 AH W+ ALA P P+LLS C G+IK+W+ + +T + H + + A+ N ++ Sbjct: 1543 AHKDWVCALAFIPGRPMLLS-ACRAGVIKVWNVD-NFTPIGEIKGHDSPINAICTNAKH- 1599 Query: 245 SVGRTTFASAALDGKAKIWD 304 +A+ D + K+W+ Sbjct: 1600 ------IFTASSDCRVKLWN 1613
>PLRG1_MOUSE (Q922V4) Pleiotropic regulator 1| Length = 513 Score = 43.9 bits (102), Expect = 4e-04 Identities = 40/170 (23%), Positives = 69/170 (40%) Frame = +2 Query: 68 HNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDS 247 H GW++ +AV P ++G ++ IK+WD G L + H + V + + ++ Sbjct: 202 HLGWVRCIAVEPGNQWFVTGSADR-TIKIWDLASGKLKL-SLTGHISTVRGVIVSTRSPY 259 Query: 248 VGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNA 427 + S D + K WD+ I + + LD ++T S A Sbjct: 260 L-----FSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLH---PTLDVLVTCSRDSTA 311 Query: 428 RIWNLRTHKCIRVIKGTSITSGAGCSVRVVYCSPDPPLLIRTFEDDSLGL 577 RIW++RT + + SG +V V C P +I D ++ L Sbjct: 312 RIWDVRTKASVHTL------SGHTNAVATVRCQAAEPQIITGSHDTTIRL 355 Score = 41.6 bits (96), Expect = 0.002 Identities = 33/125 (26%), Positives = 54/125 (43%) Frame = +2 Query: 68 HNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDS 247 H ++ + V P L S G ++ +K WD E +R ++ H + V L +P D Sbjct: 244 HISTVRGVIVSTRSPYLFSCGEDKQ-VKCWDLEYN-KVIRHYHGHLSAVYGLDLHPTLD- 300 Query: 248 VGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNA 427 + + D A+IWD+ + TL +N + + E IITGS Sbjct: 301 ----VLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRC---QAAEPQIITGSHDTTI 353 Query: 428 RIWNL 442 R+W+L Sbjct: 354 RLWDL 358 Score = 31.6 bits (70), Expect = 2.2 Identities = 16/50 (32%), Positives = 23/50 (46%) Frame = +2 Query: 50 VKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNA 199 ++ HN I LAV+ L+ G + G + LWDW G+ R A Sbjct: 405 IQNLSGHNAIINTLAVNADGVLV--SGADNGTMHLWDWRTGYNFQRVHAA 452
>PRL1_ARATH (Q42384) PP1/PP2A phosphatases pleiotropic regulator PRL1| Length = 486 Score = 43.9 bits (102), Expect = 4e-04 Identities = 42/170 (24%), Positives = 71/170 (41%) Frame = +2 Query: 62 KAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQN 241 + H GW++++A PS +G ++ IK+WD G L T H +V L + ++ Sbjct: 173 QGHLGWVRSVAFDPSNEWFCTGSADR-TIKIWDVATGVLKL-TLTGHIEQVRGLAVSNRH 230 Query: 242 DSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSG 421 T SA D + K WD+ I + +G+ L ++TG Sbjct: 231 -----TYMFSAGDDKQVKCWDLEQNKVIRSYHGHLSGVYCLALH---PTLDVLLTGGRDS 282 Query: 422 NARIWNLRTHKCIRVIKGTSITSGAGCSVRVVYCSPDPPLLIRTFEDDSL 571 R+W++RT I + G T CS V+ P P ++ D ++ Sbjct: 283 VCRVWDIRTKMQIFALSGHDNTV---CS---VFTRPTDPQVVTGSHDTTI 326 Score = 36.6 bits (83), Expect = 0.068 Identities = 26/107 (24%), Positives = 41/107 (38%), Gaps = 1/107 (0%) Frame = +2 Query: 158 DWEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLD 337 +W W R H V ++ F+P N+ F + + D KIWD++ L Sbjct: 161 EWHAPWKNYRVIQGHLGWVRSVAFDPSNE-----WFCTGSADRTIKIWDVA----TGVLK 211 Query: 338 CQSNGLIDLDYFLPGGNEQ-YIITGSLSGNARIWNLRTHKCIRVIKG 475 G I+ L N Y+ + + W+L +K IR G Sbjct: 212 LTLTGHIEQVRGLAVSNRHTYMFSAGDDKQVKCWDLEQNKVIRSYHG 258 Score = 32.7 bits (73), Expect = 0.98 Identities = 24/97 (24%), Positives = 46/97 (47%), Gaps = 2/97 (2%) Frame = +2 Query: 50 VKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTF--NAHKAKVEAL 223 ++ + H + LA+HP+L +LL+GG + ++WD T ++ F + H V ++ Sbjct: 253 IRSYHGHLSGVYCLALHPTLDVLLTGG-RDSVCRVWDIR---TKMQIFALSGHDNTVCSV 308 Query: 224 QFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATL 334 P + V + + D K WD+ ++TL Sbjct: 309 FTRPTDPQV-----VTGSHDTTIKFWDLRYGKTMSTL 340
>PRL2_ARATH (Q39190) PP1/PP2A phosphatases pleiotropic regulator PRL2| Length = 479 Score = 43.9 bits (102), Expect = 4e-04 Identities = 36/134 (26%), Positives = 58/134 (43%) Frame = +2 Query: 68 HNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDS 247 H G ++ LAV + S G ++ +K WD E+ +R+++ H V L +P D Sbjct: 211 HIGQVRGLAVSNRHTYMFSAGDDKQ-VKCWDLEQN-KVIRSYHGHLHGVYCLALHPTLDV 268 Query: 248 VGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNA 427 V + D ++WDI + I L S D+ L + +ITGS Sbjct: 269 V-----LTGGRDSVCRVWDIRTKMQIFVLPHDS----DVFSVLARPTDPQVITGSHDSTI 319 Query: 428 RIWNLRTHKCIRVI 469 + W+LR K + I Sbjct: 320 KFWDLRYGKSMATI 333 Score = 35.4 bits (80), Expect = 0.15 Identities = 23/106 (21%), Positives = 41/106 (38%) Frame = +2 Query: 158 DWEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLD 337 +W W R H V ++ F+P N+ F + + D KIWD++ + TL Sbjct: 155 EWHAPWKNYRVLQGHLGWVRSVAFDPSNE-----WFCTGSADRTIKIWDVATGVLKLTL- 208 Query: 338 CQSNGLIDLDYFLPGGNEQYIITGSLSGNARIWNLRTHKCIRVIKG 475 + + + Y+ + + W+L +K IR G Sbjct: 209 --TGHIGQVRGLAVSNRHTYMFSAGDDKQVKCWDLEQNKVIRSYHG 252 Score = 32.0 bits (71), Expect = 1.7 Identities = 23/96 (23%), Positives = 46/96 (47%), Gaps = 1/96 (1%) Frame = +2 Query: 50 VKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTF-NAHKAKVEALQ 226 ++ + H + LA+HP+L ++L+GG + ++WD T ++ F H + V ++ Sbjct: 247 IRSYHGHLHGVYCLALHPTLDVVLTGG-RDSVCRVWDIR---TKMQIFVLPHDSDVFSVL 302 Query: 227 FNPQNDSVGRTTFASAALDGKAKIWDISLILPIATL 334 P + V + + D K WD+ +AT+ Sbjct: 303 ARPTDPQV-----ITGSHDSTIKFWDLRYGKSMATI 333
>PLRG1_RAT (Q9WUC8) Pleiotropic regulator 1| Length = 514 Score = 43.9 bits (102), Expect = 4e-04 Identities = 40/170 (23%), Positives = 69/170 (40%) Frame = +2 Query: 68 HNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDS 247 H GW++ +AV P ++G ++ IK+WD G L + H + V + + ++ Sbjct: 203 HLGWVRCIAVEPGNQWFVTGSADR-TIKIWDLASGKLKL-SLTGHISTVRGVIVSTRSPY 260 Query: 248 VGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNA 427 + S D + K WD+ I + + LD ++T S A Sbjct: 261 L-----FSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLH---PTIDVLVTCSRDSTA 312 Query: 428 RIWNLRTHKCIRVIKGTSITSGAGCSVRVVYCSPDPPLLIRTFEDDSLGL 577 RIW++RT + + SG +V V C P +I D ++ L Sbjct: 313 RIWDVRTKASVHTL------SGHTNAVATVRCQAAEPQIITGSHDTTIRL 356 Score = 41.6 bits (96), Expect = 0.002 Identities = 33/125 (26%), Positives = 54/125 (43%) Frame = +2 Query: 68 HNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDS 247 H ++ + V P L S G ++ +K WD E +R ++ H + V L +P D Sbjct: 245 HISTVRGVIVSTRSPYLFSCGEDKQ-VKCWDLEYN-KVIRHYHGHLSAVYGLDLHPTID- 301 Query: 248 VGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNA 427 + + D A+IWD+ + TL +N + + E IITGS Sbjct: 302 ----VLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRC---QAAEPQIITGSHDTTI 354 Query: 428 RIWNL 442 R+W+L Sbjct: 355 RLWDL 359 Score = 31.6 bits (70), Expect = 2.2 Identities = 16/50 (32%), Positives = 23/50 (46%) Frame = +2 Query: 50 VKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNA 199 ++ HN I LAV+ L+ G + G + LWDW G+ R A Sbjct: 406 IQNLSGHNAIINTLAVNTDGVLV--SGADNGTMHLWDWRTGYNFQRVHAA 453
>PLRG1_HUMAN (O43660) Pleiotropic regulator 1| Length = 514 Score = 43.9 bits (102), Expect = 4e-04 Identities = 40/170 (23%), Positives = 69/170 (40%) Frame = +2 Query: 68 HNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDS 247 H GW++ +AV P ++G ++ IK+WD G L + H + V + + ++ Sbjct: 203 HLGWVRCIAVEPGNQWFVTGSADR-TIKIWDLASGKLKL-SLTGHISTVRGVIVSTRSPY 260 Query: 248 VGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNA 427 + S D + K WD+ I + + LD ++T S A Sbjct: 261 L-----FSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLH---PTIDVLVTCSRDSTA 312 Query: 428 RIWNLRTHKCIRVIKGTSITSGAGCSVRVVYCSPDPPLLIRTFEDDSLGL 577 RIW++RT + + SG +V V C P +I D ++ L Sbjct: 313 RIWDVRTKASVHTL------SGHTNAVATVRCQAAEPQIITGSHDTTIRL 356 Score = 41.6 bits (96), Expect = 0.002 Identities = 33/125 (26%), Positives = 54/125 (43%) Frame = +2 Query: 68 HNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDS 247 H ++ + V P L S G ++ +K WD E +R ++ H + V L +P D Sbjct: 245 HISTVRGVIVSTRSPYLFSCGEDKQ-VKCWDLEYN-KVIRHYHGHLSAVYGLDLHPTID- 301 Query: 248 VGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNA 427 + + D A+IWD+ + TL +N + + E IITGS Sbjct: 302 ----VLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRC---QAAEPQIITGSHDTTI 354 Query: 428 RIWNL 442 R+W+L Sbjct: 355 RLWDL 359 Score = 30.4 bits (67), Expect = 4.9 Identities = 18/50 (36%), Positives = 25/50 (50%) Frame = +2 Query: 50 VKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNA 199 ++ HN I L V+ S +L+SG N G + LWDW G+ R A Sbjct: 406 IQNLSGHNAIINTLTVN-SDGVLVSGADN-GTMHLWDWRTGYNFQRVHAA 453
>FBW1A_HUMAN (Q9Y297) F-box/WD-repeat protein 1A (F-box and WD-repeats protein| beta-TrCP) (E3RSIkappaB) (pIkappaBalpha-E3 receptor subunit) Length = 605 Score = 43.9 bits (102), Expect = 4e-04 Identities = 28/112 (25%), Positives = 50/112 (44%), Gaps = 2/112 (1%) Frame = +2 Query: 146 IKLWDWEKGW--TCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLIL 319 I +WD T R H+A V + F+ + SA+ D K+W+ S Sbjct: 405 IAVWDMASPTDITLRRVLVGHRAAVNVVDFDDKY-------IVSASGDRTIKVWNTSTCE 457 Query: 320 PIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNARIWNLRTHKCIRVIKG 475 + TL+ G+ L Y ++ +++GS R+W++ C+RV++G Sbjct: 458 FVRTLNGHKRGIACLQY-----RDRLVVSGSSDNTIRLWDIECGACLRVLEG 504 Score = 43.1 bits (100), Expect = 7e-04 Identities = 28/89 (31%), Positives = 41/89 (46%) Frame = +2 Query: 71 NGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDSV 250 NG + +A L+ G + I+LWD E G CLR H+ V ++F+ + Sbjct: 463 NGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECG-ACLRVLEGHEELVRCIRFDNKR--- 518 Query: 251 GRTTFASAALDGKAKIWDISLILPIATLD 337 S A DGK K+WD+ +A LD Sbjct: 519 ----IVSGAYDGKIKVWDL-----VAALD 538 Score = 32.0 bits (71), Expect = 1.7 Identities = 22/86 (25%), Positives = 37/86 (43%) Frame = +2 Query: 212 VEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNE 391 V LQ++ Q S D KIWD + + L + ++ L Y +E Sbjct: 306 VYCLQYDDQK-------IVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQY-----DE 353 Query: 392 QYIITGSLSGNARIWNLRTHKCIRVI 469 + IITGS R+W++ T + + + Sbjct: 354 RVIITGSSDSTVRVWDVNTGEMLNTL 379
>PRP46_CANAL (Q5A7Q3) Pre-mRNA-splicing factor PRP46 (Pre-mRNA-processing| protein 46) Length = 389 Score = 43.9 bits (102), Expect = 4e-04 Identities = 41/178 (23%), Positives = 65/178 (36%), Gaps = 48/178 (26%) Frame = +2 Query: 65 AHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWE-------------------------- 166 AH GWI+A+A+ G IK+WD+E Sbjct: 83 AHQGWIRAIALDEITNKWYVTGSADSTIKIWDFENNSLKAVLTGHVLGIRSLCISKRHPY 142 Query: 167 -------KGWTC-------------LRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDG 286 K C +R+++ H V ++ +P+ D S D Sbjct: 143 LFSGGEDKSLRCWDLERSNSDAGCQIRSYHGHLGGVYSIGLHPELD-----VLFSGGKDC 197 Query: 287 KAKIWDISLILPIATLDCQSNGL--IDLDYFLPGGNEQYIITGSLSGNARIWNLRTHK 454 ++WDI + TL +N + I+ DY N+ +IT S+ G R+W+LR K Sbjct: 198 VVRVWDIRSRVEAMTLLGHTNDITSIETDY-----NDPQVITSSMDGTIRLWDLRKSK 250 Score = 39.7 bits (91), Expect = 0.008 Identities = 32/185 (17%), Positives = 77/185 (41%), Gaps = 3/185 (1%) Frame = +2 Query: 47 EVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQ 226 +++ + H G + ++ +HP L +L SGG ++++WD + T H + +++ Sbjct: 167 QIRSYHGHLGGVYSIGLHPELDVLFSGG-KDCVVRVWDIRSRVEAM-TLLGHTNDITSIE 224 Query: 227 FNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIIT 406 + + V ++++DG ++WD+ + S + + E ++ Sbjct: 225 TDYNDPQV-----ITSSMDGTIRLWDLRKSKTELLITNHSKSIRSMK---SHPKEATFVS 276 Query: 407 GSLSGNARIWNLRTHKCIRVIKGTSITSGAGCSVRVV---YCSPDPPLLIRTFEDDSLGL 577 G +G + W L + + + ++ + R++ +P L ++D L Sbjct: 277 GDSNGEIKQWLLPKGELLNEFGTSQLSPNQRDNSRIINTLAINPVTNTLFSGYDDGKLEF 336 Query: 578 CNSTT 592 N TT Sbjct: 337 YNYTT 341
>KI21B_MOUSE (Q9QXL1) Kinesin family member 21B (Kinesin-like protein KIF6)| Length = 1668 Score = 43.9 bits (102), Expect = 4e-04 Identities = 38/127 (29%), Positives = 54/127 (42%), Gaps = 3/127 (2%) Frame = +2 Query: 68 HNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDS 247 H I+ LA+ + L SG + G IK WD ++ + NAHK V AL F P Sbjct: 1505 HYDGIECLAIQGDI--LFSGSRDNG-IKKWDLDQQELIQQIPNAHKDWVCALAFVP---- 1557 Query: 248 VGRTTFASAALDGKAKIWDISLILPIATL---DCQSNGLIDLDYFLPGGNEQYIITGSLS 418 GR SA G K+W++ PI + D N + N ++I T S Sbjct: 1558 -GRPMLLSACRAGFIKVWNVDNFTPIGEIKGHDSPINAICT--------NSKHIFTASSD 1608 Query: 419 GNARIWN 439 ++WN Sbjct: 1609 CRVKLWN 1615 Score = 41.2 bits (95), Expect = 0.003 Identities = 24/80 (30%), Positives = 41/80 (51%) Frame = +2 Query: 65 AHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQND 244 AH W+ ALA P P+LLS C G IK+W+ + +T + H + + A+ N ++ Sbjct: 1545 AHKDWVCALAFVPGRPMLLS-ACRAGFIKVWNVD-NFTPIGEIKGHDSPINAICTNSKH- 1601 Query: 245 SVGRTTFASAALDGKAKIWD 304 +A+ D + K+W+ Sbjct: 1602 ------IFTASSDCRVKLWN 1615
>LIS1_CAEEL (Q9NDC9) Lissencephaly-1 homolog (Pronuclear migration abnormal| protein 1) Length = 404 Score = 43.5 bits (101), Expect = 6e-04 Identities = 28/87 (32%), Positives = 44/87 (50%), Gaps = 1/87 (1%) Frame = +2 Query: 53 KKFKAHNGWIQALAVHPSLPLLLSGGCNQGL-IKLWDWEKGWTCLRTFNAHKAKVEALQF 229 + K H + +A+ + L+S C+ L IKLWD+ + + CL++ H+ V ++ F Sbjct: 142 RTLKGHTDAVNDIAIDAAGKQLVS--CSSDLSIKLWDFGQTYDCLKSLKGHEHTVSSVTF 199 Query: 230 NPQNDSVGRTTFASAALDGKAKIWDIS 310 P D V SA+ D K WDIS Sbjct: 200 LPTGDFV-----LSASRDHTIKQWDIS 221 Score = 37.7 bits (86), Expect = 0.030 Identities = 33/151 (21%), Positives = 62/151 (41%), Gaps = 10/151 (6%) Frame = +2 Query: 50 VKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQF 229 V F+ HN W++ + + L S +Q + +W + L H+ VE +++ Sbjct: 226 VYTFRGHNDWVRMIRISNDGTLFASASLDQ-TVTVWSFATKSAKL-VLRDHEHAVECVEW 283 Query: 230 NPQN--------DSVGRTTFA--SAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLP 379 P G +T S + D K W+I+ + TL N + L + Sbjct: 284 APDTAYTNVTGQQPEGNSTHILFSGSRDRSIKAWNINTGDVLFTLLAHENWVRGLAFHPK 343 Query: 380 GGNEQYIITGSLSGNARIWNLRTHKCIRVIK 472 G +Y+I+ + R+W L +C++ I+ Sbjct: 344 G---KYLISVADDKTLRVWELSAQRCMKAIE 371 Score = 35.4 bits (80), Expect = 0.15 Identities = 20/80 (25%), Positives = 39/80 (48%) Frame = +2 Query: 65 AHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQND 244 AH W++ LA HP L+S ++ L ++W+ C++ AH+ V + F+ + Sbjct: 330 AHENWVRGLAFHPKGKYLISVADDKTL-RVWEL-SAQRCMKAIEAHEHFVSTVAFHQTSP 387 Query: 245 SVGRTTFASAALDGKAKIWD 304 V + ++D K+W+ Sbjct: 388 FV-----ITGSVDMSCKVWE 402 Score = 33.9 bits (76), Expect = 0.44 Identities = 25/110 (22%), Positives = 48/110 (43%) Frame = +2 Query: 116 LLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAK 295 +L G IK W+ G L T AH+ V L F+P+ + S A D + Sbjct: 304 ILFSGSRDRSIKAWNINTG-DVLFTLLAHENWVRGLAFHPKGKYL-----ISVADDKTLR 357 Query: 296 IWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNARIWNLR 445 +W++S + ++ + + + + ++ITGS+ + ++W R Sbjct: 358 VWELSAQRCMKAIEAHEHFVSTVAFHQ---TSPFVITGSVDMSCKVWECR 404
>WD51B_MOUSE (Q8BHD1) WD-repeat protein 51B| Length = 476 Score = 43.5 bits (101), Expect = 6e-04 Identities = 38/137 (27%), Positives = 59/137 (43%), Gaps = 1/137 (0%) Frame = +2 Query: 68 HNGWIQALAVHPSLPLLLSGGCNQG-LIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQND 244 H W++ P L++S C++ IK+WD C+ F+ + FNP Sbjct: 143 HTHWVRCAKFSPDGRLIVS--CSEDKTIKIWDTTNK-QCVNNFSDSVGFANFVDFNPNG- 198 Query: 245 SVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGN 424 T ASA D KIWDI + + S G+ L F P GN ++T S G Sbjct: 199 ----TCIASAGSDHAVKIWDIRMNKLLQHYQVHSCGVNCLS-FHPLGNS--LVTASSDGT 251 Query: 425 ARIWNLRTHKCIRVIKG 475 ++ +L + I ++G Sbjct: 252 VKMLDLIEGRLIYTLQG 268
>PRP17_MOUSE (Q9DC48) Pre-mRNA-splicing factor PRP17 (Cell division cycle 40| homolog) Length = 579 Score = 43.5 bits (101), Expect = 6e-04 Identities = 31/97 (31%), Positives = 41/97 (42%) Frame = +2 Query: 14 PPAXCKTLGLEEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTF 193 PP C L +++ + H + A+ + P LL IKLW+ CLRTF Sbjct: 270 PPEKCY-LPKKQIHVWSGHTKGVSAVRLFPLSGHLLLSCSMDCKIKLWEVYGDRRCLRTF 328 Query: 194 NAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWD 304 H V + FN T F SAA D K+WD Sbjct: 329 IGHSKAVRDICFN-----TAGTQFLSAAYDRYLKLWD 360
>HAT2_NEUCR (Q7S7N3) Histone acetyltransferase type B subunit 2 (EC 2.3.1.48)| Length = 564 Score = 43.5 bits (101), Expect = 6e-04 Identities = 29/119 (24%), Positives = 55/119 (46%) Frame = +2 Query: 68 HNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDS 247 H+ I ALA +P + +++ I +WD + + T H+ V +L+++P + Sbjct: 287 HSDAINALAFNPRVETIIATASADKTIGIWDMRNMKSKVHTLEGHQDAVTSLEWHPTESA 346 Query: 248 VGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGN 424 + S + D + WDIS + T D +G +L F+ GG+ ++ S + N Sbjct: 347 I----LGSGSYDRRLLFWDISRVGDEQTQDDAEDGPPEL-LFMHGGHTNHLADFSWNRN 400
>GBB4_HUMAN (Q9HAV0) Guanine nucleotide-binding protein beta subunit 4| (Transducin beta chain 4) Length = 339 Score = 43.5 bits (101), Expect = 6e-04 Identities = 23/88 (26%), Positives = 44/88 (50%) Frame = +2 Query: 44 EEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEAL 223 ++ F H+G + +L++ P + +SG C+ KLWD G C ++F H + + A+ Sbjct: 174 QQTTTFTGHSGDVMSLSLSPDMRTFVSGACDAS-SKLWDIRDG-MCRQSFTGHVSDINAV 231 Query: 224 QFNPQNDSVGRTTFASAALDGKAKIWDI 307 F P FA+ + D +++D+ Sbjct: 232 SFFPNG-----YAFATGSDDATCRLFDL 254 Score = 36.6 bits (83), Expect = 0.068 Identities = 26/90 (28%), Positives = 41/90 (45%) Frame = +2 Query: 185 RTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDL 364 RT H AK+ A+ + + SA+ DGK IWD + + +S+ ++ Sbjct: 48 RTLRGHLAKIYAMHWGYDS-----RLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTC 102 Query: 365 DYFLPGGNEQYIITGSLSGNARIWNLRTHK 454 Y P GN Y+ G L I+NL+T + Sbjct: 103 AY-APSGN--YVACGGLDNICSIYNLKTRE 129
>GBLP_DICDI (P46800) Guanine nucleotide-binding protein beta subunit-like| protein Length = 329 Score = 43.5 bits (101), Expect = 6e-04 Identities = 44/169 (26%), Positives = 70/169 (41%), Gaps = 6/169 (3%) Frame = +2 Query: 53 KKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFN 232 + K H+ ++Q + + LSG + L +LWD KG R F H V ++ F+ Sbjct: 64 RSLKGHSHFVQDVVISHDGQFALSGSWDNTL-RLWDITKG-VSTRLFKGHTQDVMSVAFS 121 Query: 233 PQNDSVGRTTFASAALDGKAKIWD------ISLILPIATLDCQSNGLIDLDYFLPGGNEQ 394 N + S + D K+W+ +L P A D + F P N Sbjct: 122 SDNRQI-----ISGSRDATIKVWNTLGECKFTLEGPEAHQDW-----VSCIRFSP--NTP 169 Query: 395 YIITGSLSGNARIWNLRTHKCIRVIKGTSITSGAGCSVRVVYCSPDPPL 541 I++GS +IW++++ KC ++T G V V SPD L Sbjct: 170 TIVSGSWDNKVKIWDIKSFKC-----NHTLTDHTG-YVNTVTISPDGSL 212 Score = 36.6 bits (83), Expect = 0.068 Identities = 34/194 (17%), Positives = 75/194 (38%), Gaps = 5/194 (2%) Frame = +2 Query: 47 EVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLW-----DWEKGWTCLRTFNAHKAK 211 EV HNG++ ++AV P P + + +W D R+ H Sbjct: 13 EVGSLVGHNGFVTSIAVSPENPDTIISSSRDKTVMVWQLTPTDATSPGKAHRSLKGHSHF 72 Query: 212 VEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNE 391 V+ + + S + D ++WDI+ + + ++ + + + Sbjct: 73 VQDVVISHDGQFA-----LSGSWDNTLRLWDITKGVSTRLFKGHTQDVMSVAF---SSDN 124 Query: 392 QYIITGSLSGNARIWNLRTHKCIRVIKGTSITSGAGCSVRVVYCSPDPPLLIRTFEDDSL 571 + II+GS ++WN +C ++G +R SP+ P ++ D+ + Sbjct: 125 RQIISGSRDATIKVWN-TLGECKFTLEGPEAHQDWVSCIRF---SPNTPTIVSGSWDNKV 180 Query: 572 GLCNSTTFRYTNTI 613 + + +F+ +T+ Sbjct: 181 KIWDIKSFKCNHTL 194 Score = 32.3 bits (72), Expect = 1.3 Identities = 25/93 (26%), Positives = 38/93 (40%), Gaps = 6/93 (6%) Frame = +2 Query: 47 EVKKFKA------HNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKA 208 ++K FK H G++ + + P L SGG LW+ G + + Sbjct: 184 DIKSFKCNHTLTDHTGYVNTVTISPDGSLCASGG-KDTFACLWELSSGKPLYKL--EARN 240 Query: 209 KVEALQFNPQNDSVGRTTFASAALDGKAKIWDI 307 + AL F+P + SAA D K IWD+ Sbjct: 241 TINALAFSPNK------YWLSAATDDKIIIWDL 267
>RCO1_NEUCR (P78706) Transcriptional repressor rco-1| Length = 604 Score = 43.5 bits (101), Expect = 6e-04 Identities = 29/100 (29%), Positives = 49/100 (49%) Frame = +2 Query: 17 PAXCKTLGLEEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFN 196 P+ G +K F+ H ++ ++A+ P +LSG ++G ++ WD G T L Sbjct: 507 PSSAPPKGGRCIKTFEGHRDFVLSVALTPDSQWVLSGSKDRG-VQFWDPRTGHTQLM-LQ 564 Query: 197 AHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLI 316 HK V ++ +P G FA+ + D +A+IW S I Sbjct: 565 GHKNSVISVAPSPVTGPNGVGYFATGSGDMRARIWSYSRI 604 Score = 43.1 bits (100), Expect = 7e-04 Identities = 38/138 (27%), Positives = 64/138 (46%) Frame = +2 Query: 119 LSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKI 298 L+ G LI++WD + T TF+ H+ + +L F+ GRT AS + D ++ Sbjct: 359 LATGAEDKLIRVWDIQSR-TIRNTFHGHEQDIYSLDFSRD----GRT-IASGSGDRTVRL 412 Query: 299 WDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNARIWNLRTHKCIRVIKGT 478 WDI + L + + ++Q++ GSL + R+W++R + R ++G Sbjct: 413 WDIETGQNTSVLSIEDG----VTTVAISPDKQFVAAGSLDKSVRVWDMRGYLAER-LEG- 466 Query: 479 SITSGAGCSVRVVYCSPD 532 G SV V SPD Sbjct: 467 --PDGHKDSVYSVAFSPD 482
>LIN23_CAEEL (Q09990) F-box/WD-repeat protein lin-23 (Abnormal cell lineage| protein 23) Length = 665 Score = 43.1 bits (100), Expect = 7e-04 Identities = 28/93 (30%), Positives = 39/93 (41%) Frame = +2 Query: 41 LEEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEA 220 LE V+ H I L L + G + I+LWD G CLR H+ V Sbjct: 375 LEFVRTLAGHRRGIACLQYRGRLVV---SGSSDNTIRLWDIHSG-VCLRVLEGHEELVRC 430 Query: 221 LQFNPQNDSVGRTTFASAALDGKAKIWDISLIL 319 ++F+ + S A DGK K+WD+ L Sbjct: 431 IRFDEKR-------IVSGAYDGKIKVWDLQAAL 456 Score = 42.0 bits (97), Expect = 0.002 Identities = 27/112 (24%), Positives = 50/112 (44%), Gaps = 2/112 (1%) Frame = +2 Query: 146 IKLWDW--EKGWTCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLIL 319 I +WD + T R H+A V + F+ + SA+ D K+W + + Sbjct: 324 IAVWDMVSPRDITIRRVLVGHRAAVNVVDFDDRY-------IVSASGDRTIKVWSMDTLE 376 Query: 320 PIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNARIWNLRTHKCIRVIKG 475 + TL G+ L Y + +++GS R+W++ + C+RV++G Sbjct: 377 FVRTLAGHRRGIACLQY-----RGRLVVSGSSDNTIRLWDIHSGVCLRVLEG 423 Score = 32.0 bits (71), Expect = 1.7 Identities = 18/67 (26%), Positives = 30/67 (44%) Frame = +2 Query: 269 SAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNARIWNLRT 448 S D KIWD L + ++ L Y + + II+GS R+W++ T Sbjct: 237 SGLRDNTIKIWDRKDYSCSRILSGHTGSVLCLQY-----DNRVIISGSSDATVRVWDVET 291 Query: 449 HKCIRVI 469 +CI+ + Sbjct: 292 GECIKTL 298
>WSB2_MOUSE (O54929) WD repeat and SOCS box-containing protein 2 (WSB-2) (SOCS| box-containing WD protein SWiP-2) Length = 404 Score = 43.1 bits (100), Expect = 7e-04 Identities = 44/174 (25%), Positives = 72/174 (41%), Gaps = 16/174 (9%) Frame = +2 Query: 98 HPSLP----LLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRTTF 265 HP P L+L+ G N G IK+W+ + G L + H+ V L F P G Sbjct: 115 HPQAPDVSCLILATGLNDGQIKIWEVQTG-LLLLNLSGHQDVVRDLSFTPS----GSLIL 169 Query: 266 ASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNAR----- 430 SA+ D +IWD++ +G + G+ Q++ S+S + Sbjct: 170 VSASRDKTLRIWDLN-----------KHG---KQIQVLSGHLQWVYCCSISPDCSMLCSA 215 Query: 431 -------IWNLRTHKCIRVIKGTSITSGAGCSVRVVYCSPDPPLLIRTFEDDSL 571 +W++R++ IR ++G +S C SPD LL+ D S+ Sbjct: 216 AGEKSVFLWSMRSYTLIRKLEGHQ-SSVVSCDF-----SPDSALLVTASYDTSV 263 Score = 40.0 bits (92), Expect = 0.006 Identities = 35/126 (27%), Positives = 58/126 (46%), Gaps = 4/126 (3%) Frame = +2 Query: 230 NPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITG 409 +PQ V A+ DG+ KIW++ L + L + + DL F P G+ +++ Sbjct: 115 HPQAPDVSCLILATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLS-FTPSGS-LILVSA 172 Query: 410 SLSGNARIWNLRTH-KCIRVIKGTSITSGAGCSVRVVYC---SPDPPLLIRTFEDDSLGL 577 S RIW+L H K I+V+ G ++ VYC SPD +L + S+ L Sbjct: 173 SRDKTLRIWDLNKHGKQIQVLSG---------HLQWVYCCSISPDCSMLCSAAGEKSVFL 223 Query: 578 CNSTTF 595 + ++ Sbjct: 224 WSMRSY 229
>PRP17_HUMAN (O60508) Pre-mRNA-splicing factor PRP17 (hPRP17) (Cell division| cycle 40 homolog) (EH-binding protein 3) (Ehb3) Length = 579 Score = 43.1 bits (100), Expect = 7e-04 Identities = 31/97 (31%), Positives = 41/97 (42%) Frame = +2 Query: 14 PPAXCKTLGLEEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTF 193 PP C L +++ + H + A+ + P LL IKLW+ CLRTF Sbjct: 270 PPEKCY-LPKKQIHVWSGHTKGVSAVRLFPLSGHLLLSCSMDCKIKLWEVYGERRCLRTF 328 Query: 194 NAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWD 304 H V + FN T F SAA D K+WD Sbjct: 329 IGHSKAVRDICFN-----TAGTQFLSAAYDRYLKLWD 360
>HAT2_ASPFU (Q4WEI5) Histone acetyltransferase type B subunit 2 (EC 2.3.1.48)| Length = 436 Score = 43.1 bits (100), Expect = 7e-04 Identities = 25/81 (30%), Positives = 40/81 (49%) Frame = +2 Query: 68 HNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDS 247 H I A+A +P+ +L+ G I LWD T L + +H V ++ ++P ++ Sbjct: 285 HRDAINAIAFNPAAETVLATGSADKTIGLWDLRNLKTKLHSLESHTDSVTSISWHPFEEA 344 Query: 248 VGRTTFASAALDGKAKIWDIS 310 V ASA+ D K WD+S Sbjct: 345 V----LASASYDRKIAFWDLS 361 Score = 34.3 bits (77), Expect = 0.34 Identities = 34/135 (25%), Positives = 55/135 (40%), Gaps = 13/135 (9%) Frame = +2 Query: 200 HKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLP 379 HK +V ++ PQN ++ A+ DG+ +WD S + T G ++ L Sbjct: 137 HKGEVNKARYQPQNPNI----IATMCTDGRVMVWDRSKHPSLPT------GQVNPQMELI 186 Query: 380 GGNEQ------------YIITGSLSGNARIWNLRTH-KCIRVIKGTSITSGAGCSVRVVY 520 G ++ + TGS RIW+L T+ K +++K + + V V Sbjct: 187 GHTKEGFGLSWSPHTAGQLATGSEDKTVRIWDLTTYSKGNKLLKPSRTYTHHSSIVNDVQ 246 Query: 521 CSPDPPLLIRTFEDD 565 P LI T DD Sbjct: 247 YHPLHSSLIGTVSDD 261 Score = 30.8 bits (68), Expect = 3.7 Identities = 26/122 (21%), Positives = 44/122 (36%), Gaps = 21/122 (17%) Frame = +2 Query: 68 HNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDS 247 H G + P P +++ C G + +WD K + Q NPQ + Sbjct: 137 HKGEVNKARYQPQNPNIIATMCTDGRVMVWDRSK-----------HPSLPTGQVNPQMEL 185 Query: 248 VGRT--------------TFASAALDGKAKIWDIS-------LILPIATLDCQSNGLIDL 364 +G T A+ + D +IWD++ L+ P T S+ + D+ Sbjct: 186 IGHTKEGFGLSWSPHTAGQLATGSEDKTVRIWDLTTYSKGNKLLKPSRTYTHHSSIVNDV 245 Query: 365 DY 370 Y Sbjct: 246 QY 247
>CORO_DICDI (P27133) Coronin (p55)| Length = 445 Score = 42.7 bits (99), Expect = 0.001 Identities = 35/146 (23%), Positives = 60/146 (41%), Gaps = 6/146 (4%) Frame = +2 Query: 50 VKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGW------TCLRTFNAHKAK 211 V F H + +A HP L+ I +W +G T L+T + HK K Sbjct: 72 VPLFNGHKSAVLDIAFHPFNENLVGSVSEDCNICIWGIPEGGLTDSISTPLQTLSGHKRK 131 Query: 212 VEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNE 391 V + F P D+V T+ D K WD+ + T++ S+ + ++ N Sbjct: 132 VGTISFGPVADNVAVTSSG----DFLVKTWDVEQGKNLTTVEGHSDMITSCEW---NHNG 184 Query: 392 QYIITGSLSGNARIWNLRTHKCIRVI 469 I+T AR+++ RT+ + + Sbjct: 185 SQIVTTCKDKKARVFDPRTNSIVNEV 210
>PK1IP_BOVIN (Q5EA99) p21-activated protein kinase-interacting protein 1| (PAK1-interacting protein 1) Length = 392 Score = 42.7 bits (99), Expect = 0.001 Identities = 27/80 (33%), Positives = 37/80 (46%) Frame = +2 Query: 68 HNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDS 247 HNG I L H + L+ G GLI +WD + W CL++ AHK V L +P Sbjct: 81 HNGTITCLKFHGNRHLI--SGAEDGLICVWDARR-WECLKSIRAHKGHVTFLSIHPS--- 134 Query: 248 VGRTTFASAALDGKAKIWDI 307 GR S D + W++ Sbjct: 135 -GRLAL-SVGTDKTLRTWNL 152 Score = 30.4 bits (67), Expect = 4.9 Identities = 16/43 (37%), Positives = 26/43 (60%) Frame = +2 Query: 44 EEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKG 172 E +K +AH G + L++HPS L LS G ++ L + W+ +G Sbjct: 114 ECLKSIRAHKGHVTFLSIHPSGRLALSVGTDKTL-RTWNLVEG 155
>PK1IP_XENLA (Q68FJ6) p21-activated protein kinase-interacting protein 1-like| (PAK1-interacting protein 1-like) Length = 363 Score = 42.7 bits (99), Expect = 0.001 Identities = 23/56 (41%), Positives = 32/56 (57%) Frame = +2 Query: 68 HNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNP 235 HNG I L + + LL G GLI +W+ +K W C +TF AHK +V +L +P Sbjct: 79 HNGTITCLEFYGNTHLL--SGAEDGLICVWNTKK-WECQQTFKAHKGQVLSLSIHP 131 Score = 32.3 bits (72), Expect = 1.3 Identities = 16/38 (42%), Positives = 25/38 (65%) Frame = +2 Query: 59 FKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKG 172 FKAH G + +L++HPS L LS G ++ L + W+ +G Sbjct: 117 FKAHKGQVLSLSIHPSGKLALSVGTDKTL-RTWNLVEG 153
>PRP46_ASHGO (Q75BY3) Pre-mRNA-splicing factor PRP46 (Pre-mRNA-processing| protein 46) Length = 425 Score = 42.7 bits (99), Expect = 0.001 Identities = 36/194 (18%), Positives = 75/194 (38%) Frame = +2 Query: 68 HNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDS 247 H GW++ + V P + G N I++WD G + T H V + + ++ Sbjct: 112 HTGWVRCVCVDPVDNAWFATGSNDSTIRVWDLATGKLKV-TLQGHIMTVRDICISARHPY 170 Query: 248 VGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNA 427 + SA+ D K WD+ + +G+ +D + I++ Sbjct: 171 M-----FSASQDKLVKCWDLERNTVVRDFHGTLSGVHSVDLH---PSLDLIVSAGRDSVV 222 Query: 428 RIWNLRTHKCIRVIKGTSITSGAGCSVRVVYCSPDPPLLIRTFEDDSLGLCNSTTFRYTN 607 R+W++R+ C+ + +G + V C P P ++ D ++ L + + Sbjct: 223 RVWDIRSRSCVLTL------AGHRGPINKVRCLPVDPQIVSCSTDATVKLWDLVAGKPMK 276 Query: 608 TIDFGLLRARNIVY 649 T+ R++ + Sbjct: 277 TLTHHKRNVRDLAF 290 Score = 31.6 bits (70), Expect = 2.2 Identities = 25/72 (34%), Positives = 32/72 (44%) Frame = +2 Query: 68 HNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDS 247 H G I + P P ++S + +KLWD G ++T HK V L FNP S Sbjct: 239 HRGPINKVRCLPVDPQIVSCSTD-ATVKLWDLVAGKP-MKTLTHHKRNVRDLAFNPTEFS 296 Query: 248 VGRTTFASAALD 283 FASA D Sbjct: 297 -----FASACTD 303
>PWP2_SCHPO (Q9C1X1) Periodic tryptophan protein 2 homolog| Length = 854 Score = 42.7 bits (99), Expect = 0.001 Identities = 32/117 (27%), Positives = 52/117 (44%), Gaps = 1/117 (0%) Frame = +2 Query: 128 GCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDI 307 G + G IK+WD G+ C+ TF H + V L F+ + G F+S+ LDG + WD+ Sbjct: 357 GADDGKIKVWDMNSGF-CIVTFTQHTSAVSGLCFSKR----GNVLFSSS-LDGSVRAWDL 410 Query: 308 SLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSL-SGNARIWNLRTHKCIRVIKG 475 T S P G + + GS S +W+++T + + + G Sbjct: 411 IRYRNFRTFTAPSRVQFSCIAVDPSG--EIVCAGSQDSFEIFMWSVQTGQLLETLAG 465 Score = 36.2 bits (82), Expect = 0.088 Identities = 37/148 (25%), Positives = 65/148 (43%), Gaps = 1/148 (0%) Frame = +2 Query: 71 NGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDSV 250 N ++ A HP+ LL+ G + GL +++ +T L + ++ ++ L N D + Sbjct: 254 NSKLRCAAFHPTSNLLVVG-FSSGLFGIYELPS-FTMLYQLSITQSNIDTLTVNSTGDWI 311 Query: 251 GRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNAR 430 S+ L G+ +W+ + + L L Y G Q IITG+ G + Sbjct: 312 A---IGSSKL-GQLLVWEWQSESYVLKQQSHYDALSTLQYSSDG---QRIITGADDGKIK 364 Query: 431 IWNLRTHKCI-RVIKGTSITSGAGCSVR 511 +W++ + CI + TS SG S R Sbjct: 365 VWDMNSGFCIVTFTQHTSAVSGLCFSKR 392
>PWP2_CAEEL (P91341) Periodic tryptophan protein 2 homolog| Length = 910 Score = 42.7 bits (99), Expect = 0.001 Identities = 28/120 (23%), Positives = 57/120 (47%), Gaps = 3/120 (2%) Frame = +2 Query: 119 LSGGCNQGL---IKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGK 289 L+ GC +G + +W+W+ ++ AH ++ +++P + A+ A DGK Sbjct: 330 LAIGCGKGSTAQLVVWEWQSESYVMKQ-QAHSLRITTAEYSPDG-----SLMATGAEDGK 383 Query: 290 AKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNARIWNLRTHKCIRVI 469 KIW+ T D ++G+ + + G + I++ SL G R +L+ ++ R + Sbjct: 384 VKIWNSRSSFCTVTFDEHTSGVTAVKWTQSG---RAILSASLDGTVRAHDLKRYRNFRTL 440
>WSB2_HUMAN (Q9NYS7) WD repeat and SOCS box-containing protein 2 (WSB-2) (CS| box-containing WD protein) Length = 404 Score = 42.4 bits (98), Expect = 0.001 Identities = 43/174 (24%), Positives = 73/174 (41%), Gaps = 16/174 (9%) Frame = +2 Query: 98 HPSLP----LLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRTTF 265 HP +P L+L+ G N G IK+W+ + G L + H+ V L F P G Sbjct: 115 HPQVPDVSCLVLATGLNDGQIKIWEVQTG-LLLLNLSGHQDVVRDLSFTPS----GSLIL 169 Query: 266 ASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNAR----- 430 SA+ D +IWD++ +G + G+ Q++ S+S + Sbjct: 170 VSASRDKTLRIWDLN-----------KHG---KQIQVLSGHLQWVYCCSISPDCSMLCSA 215 Query: 431 -------IWNLRTHKCIRVIKGTSITSGAGCSVRVVYCSPDPPLLIRTFEDDSL 571 +W++R++ IR ++G +S C SPD LL+ D ++ Sbjct: 216 AGEKSVFLWSMRSYTLIRKLEGHQ-SSVVSCDF-----SPDSALLVTASYDTNV 263 Score = 40.0 bits (92), Expect = 0.006 Identities = 35/126 (27%), Positives = 58/126 (46%), Gaps = 4/126 (3%) Frame = +2 Query: 230 NPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITG 409 +PQ V A+ DG+ KIW++ L + L + + DL F P G+ +++ Sbjct: 115 HPQVPDVSCLVLATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLS-FTPSGS-LILVSA 172 Query: 410 SLSGNARIWNLRTH-KCIRVIKGTSITSGAGCSVRVVYC---SPDPPLLIRTFEDDSLGL 577 S RIW+L H K I+V+ G ++ VYC SPD +L + S+ L Sbjct: 173 SRDKTLRIWDLNKHGKQIQVLSG---------HLQWVYCCSISPDCSMLCSAAGEKSVFL 223 Query: 578 CNSTTF 595 + ++ Sbjct: 224 WSMRSY 229
>STRN_RAT (P70483) Striatin| Length = 780 Score = 42.4 bits (98), Expect = 0.001 Identities = 42/203 (20%), Positives = 82/203 (40%), Gaps = 10/203 (4%) Frame = +2 Query: 14 PPAXCKTLGLEEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTF 193 P +L +E + F+AH G + + + + SGG GLI+ W + + Sbjct: 497 PAKKSTSLDVEPIYTFRAHKGPVLCVVMSSNGEQCYSGG-TDGLIQSWSTTN--PNVDPY 553 Query: 194 NAHKAKVEALQFNPQNDSVGRTTFASA-------ALDGKAKIWDISLILPIATL--DCQS 346 +++ V D+V +++A + DG ++W + + P T+ D Q Sbjct: 554 DSYDPSVLRGPLLGHTDAVWGLAYSAAHQRLLSCSADGTLRLWTTTEVAPALTVFNDNQE 613 Query: 347 NGLIDLDYFLPGGNEQYIITGSLSGNARIWNLRTHKCIRVIK-GTSITSGAGCSVRVVYC 523 G I L + +++ G I+N+ T + I ++ T+ + C + V Sbjct: 614 LG-IPASVDLVSSDPSHMVASFSKGYTSIFNMETQQRILTLESNVDSTASSSCQINRVIS 672 Query: 524 SPDPPLLIRTFEDDSLGLCNSTT 592 P P+ I ED + ++ T Sbjct: 673 HPTLPISITAHEDRHIKFYDNNT 695 Score = 36.6 bits (83), Expect = 0.068 Identities = 28/83 (33%), Positives = 42/83 (50%), Gaps = 4/83 (4%) Frame = +2 Query: 65 AHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEA----LQFN 232 AH + +LAV P+ L L G + I+LW+ E TC++ F AH+ K E + F+ Sbjct: 704 AHLEAVTSLAVDPN-GLYLMSGSHDCSIRLWNLESK-TCIQEFTAHRKKFEESIHDVAFH 761 Query: 233 PQNDSVGRTTFASAALDGKAKIW 301 P + ASA D AK++ Sbjct: 762 P-----SKCYIASAGADALAKVF 779
>SWD3_YEAST (P38123) COMPASS component SWD3 (Complex proteins associated with| SET1 protein SWD3) (Set1C component SWD3) Length = 315 Score = 42.4 bits (98), Expect = 0.001 Identities = 40/159 (25%), Positives = 70/159 (44%), Gaps = 10/159 (6%) Frame = +2 Query: 32 TLGLEEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAH--- 202 TL +K AH+ + ++ V + +LS G GLI+++D E G CL+T Sbjct: 125 TLNGSLMKTISAHSEAVVSVDVPMNDSSILSSGSYDGLIRIFDAETG-HCLKTLTYDKDW 183 Query: 203 KAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQ--SNGLI----DL 364 K + + + S +LDG KIWD + T Q G++ + Sbjct: 184 KRENGVVPISQVKFSENARYLLVKSLDGVVKIWDCIGGCVVRTFQVQPLEKGVLHHSCGM 243 Query: 365 DYFLP-GGNEQYIITGSLSGNARIWNLRTHKCIRVIKGT 478 D+ P G+ +I+G +G+ WN T ++++ G+ Sbjct: 244 DFLNPEDGSTPLVISGYENGDIYCWNSDTKSLLQLLDGS 282
>TIPD_DICDI (O15736) Protein tipD| Length = 612 Score = 42.4 bits (98), Expect = 0.001 Identities = 37/139 (26%), Positives = 64/139 (46%) Frame = +2 Query: 53 KKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFN 232 K++ HN I +A + LL +GG ++ +K+WD G A ++ V ++ F+ Sbjct: 318 KRWTGHNSEIYCMAFNSIGNLLATGGGDK-CVKVWDVISGQQKSTLLGASQSIV-SVSFS 375 Query: 233 PQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGS 412 P ++S+ T+ D A++W+ L TL G I Y N ++TGS Sbjct: 376 PNDESILGTSN-----DNSARLWNTELGRSRHTL----TGHIGKVYTGKFINSNRVVTGS 426 Query: 413 LSGNARIWNLRTHKCIRVI 469 ++W+L+ C R I Sbjct: 427 HDRTIKLWDLQKGYCTRTI 445 Score = 29.6 bits (65), Expect = 8.3 Identities = 34/146 (23%), Positives = 61/146 (41%), Gaps = 8/146 (5%) Frame = +2 Query: 119 LSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKI 298 L+ G ++ WD G + H+ ++ ++ +P N + T + D KI Sbjct: 464 LASGHVDHSVRFWDSNAGEPTQVLSSIHEGQITSITNSPTNTNQILTN----SRDHTLKI 519 Query: 299 WDISLILPIATLDCQS--NGLI-DLDYFLPGGNEQYIITGSLSGNARIWNLRTHKCIRVI 469 DI I T NGL + P G +YI +GS+ G+ IW+ K ++V+ Sbjct: 520 IDIRTFDTIRTFKDPEYRNGLNWTKASWSPDG--RYIASGSIDGSICIWDATNGKTVKVL 577 Query: 470 -----KGTSITSGAGCSVRVVYCSPD 532 G+S+ + + ++ S D Sbjct: 578 TKVHNNGSSVCCCSWSPLANIFISAD 603
>BRWD1_HUMAN (Q9NSI6) Bromodomain and WD-repeat domain-containing protein 1| (WD-repeat protein 9) Length = 2320 Score = 42.0 bits (97), Expect = 0.002 Identities = 23/104 (22%), Positives = 46/104 (44%), Gaps = 1/104 (0%) Frame = +2 Query: 128 GCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDI 307 G + L+K+W G L T H A++ + N +N T A+ + D ++W + Sbjct: 204 GSDDCLVKIWSTHNG-RLLSTLRGHSAEISDMAVNYEN-----TMIAAGSCDKIIRVWCL 257 Query: 308 SLILPIATLDCQSNGLIDLDYF-LPGGNEQYIITGSLSGNARIW 436 P+A L + + L + + G+++Y+++ G W Sbjct: 258 RTCAPVAVLQGHTGSITSLQFSPMAKGSQRYMVSTGADGTVCFW 301
>STRN3_MOUSE (Q9ERG2) Striatin-3 (Cell-cycle autoantigen SG2NA) (S/G2 antigen)| Length = 796 Score = 42.0 bits (97), Expect = 0.002 Identities = 47/208 (22%), Positives = 91/208 (43%), Gaps = 15/208 (7%) Frame = +2 Query: 14 PPAXCKTLGLEEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTF 193 P +L +E + F+AH G + +LA+ + SGG + + W W + + Sbjct: 513 PAKKSASLDVEPIYTFRAHIGPVLSLAISSNGEQCFSGGIDATI--QW-WNMPSPNVDPY 569 Query: 194 NAHKAKVEALQFNPQNDSVGRTTFA-------SAALDGKAKIWDISLILPIATLDCQSNG 352 + +++ V A D+V ++ S + DG ++W+ LP C NG Sbjct: 570 DTYESNVLAGTLVAHTDAVWGLAYSGIKNQLLSCSADGTIRLWNPQEKLPCV---CTYNG 626 Query: 353 LIDLDYFLP------GGNEQYIITGSLSGNARIWNLRTHKCIRVIKGTSITSGAGCS--V 508 D ++ +P G + +++T +G+A I++L T + + V+ + + SG S + Sbjct: 627 --DKEHGIPTSVDFIGCDPAHMVTSFNTGSAVIYDLETSQSL-VMLSSQVDSGLQSSNHI 683 Query: 509 RVVYCSPDPPLLIRTFEDDSLGLCNSTT 592 V P P+ I ED + ++ T Sbjct: 684 NRVVSHPTLPVTITAHEDRHIKFFDNKT 711 Score = 35.0 bits (79), Expect = 0.20 Identities = 51/221 (23%), Positives = 91/221 (41%), Gaps = 27/221 (12%) Frame = +2 Query: 62 KAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTC----------LRTFNAHKAK 211 ++H ++ALA HP P+L++ +KLW+ +K + TF AH Sbjct: 476 RSHFDGVRALAFHPVEPVLVTAS-EDHTLKLWNLQKTVPAKKSASLDVEPIYTFRAHIGP 534 Query: 212 VEALQFNPQNDSVGRTTFASAALDGKAKIWDI------------SLILPIATLDCQSNGL 355 V +L + S G F S +D + W++ S +L TL ++ + Sbjct: 535 VLSLAIS----SNGEQCF-SGGIDATIQWWNMPSPNVDPYDTYESNVL-AGTLVAHTDAV 588 Query: 356 IDLDYFLPGGNEQYIITGSLSGNARIWNLRTH-KCIRVIKGTSITSGAGCSVRVVYCSPD 532 L Y G + +++ S G R+WN + C+ G G SV + C D Sbjct: 589 WGLAY---SGIKNQLLSCSADGTIRLWNPQEKLPCVCTYNGDK-EHGIPTSVDFIGC--D 642 Query: 533 PPLLIRTFEDDSLGLCNSTTFR----YTNTIDFGLLRARNI 643 P ++ +F S + + T + ++ +D GL + +I Sbjct: 643 PAHMVTSFNTGSAVIYDLETSQSLVMLSSQVDSGLQSSNHI 683
>WDR47_HUMAN (O94967) WD-repeat protein 47| Length = 919 Score = 42.0 bits (97), Expect = 0.002 Identities = 50/177 (28%), Positives = 71/177 (40%), Gaps = 5/177 (2%) Frame = +2 Query: 53 KKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRT-----FNAHKAKVE 217 K+ K H G I +A P LL +G N +K+ + TC T F+ H + Sbjct: 655 KRNKHHKGSIYCVAWSPCGQLLATGS-NDKYVKVLPFNAE-TCNATGPDLEFSMHDGTIR 712 Query: 218 ALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQY 397 L F +S G ++ A D D + L + ++ L Y G Sbjct: 713 DLAFMEGPESGGAILISAGAGDCNIYTTDCQRGQGLHALSGHTGHILAL-YTWSGW---M 768 Query: 398 IITGSLSGNARIWNLRTHKCIRVIKGTSITSGAGCSVRVVYCSPDPPLLIRTFEDDS 568 I +GS R W+LR C+RV+ GT+ G G +V V P LL ED S Sbjct: 769 IASGSQDKTVRFWDLRVPSCVRVV-GTTF-HGTGSAVASVAVDPSGRLLATGQEDSS 823
>PWP2_MOUSE (Q8BU03) Periodic tryptophan protein 2 homolog| Length = 919 Score = 42.0 bits (97), Expect = 0.002 Identities = 29/128 (22%), Positives = 56/128 (43%) Frame = +2 Query: 80 IQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRT 259 + ++A++ S + G G + +W+W+ L+ H + AL ++P + Sbjct: 333 VASVAINSSGDWIAFGCSGMGQLLVWEWQSESYVLKQ-QGHFNSMVALAYSPDGQYI--- 388 Query: 260 TFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNARIWN 439 + DGK K+W+ TL S+G+ + + G I+T SL G R ++ Sbjct: 389 --VTGGDDGKVKVWNTLSGFCFVTLTEHSSGVTGVTFTTTG---HVIVTSSLDGTVRAFD 443 Query: 440 LRTHKCIR 463 L ++ R Sbjct: 444 LHRYRNFR 451 Score = 30.4 bits (67), Expect = 4.9 Identities = 26/126 (20%), Positives = 54/126 (42%) Frame = +2 Query: 80 IQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRT 259 + + A H LL++G + G+ L + + + + + + +V ++ N D + Sbjct: 291 LTSAAYHKKTHLLVTGFAS-GIFHLHELPE-FNLIHSLSISDQRVASVAINSSGDWIA-- 346 Query: 260 TFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNARIWN 439 F + + G+ +W+ + N ++ L Y G QYI+TG G ++WN Sbjct: 347 -FGCSGM-GQLLVWEWQSESYVLKQQGHFNSMVALAYSPDG---QYIVTGGDDGKVKVWN 401 Query: 440 LRTHKC 457 + C Sbjct: 402 TLSGFC 407
>PRP4_ARATH (O22212) U4/U6 small nuclear ribonucleoprotein PRP4-like protein| Length = 554 Score = 42.0 bits (97), Expect = 0.002 Identities = 26/105 (24%), Positives = 48/105 (45%) Frame = +2 Query: 161 WEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDC 340 W+ T L+TF H ++ + F+P +G T++ D ++WDI+ + + Sbjct: 325 WKTDGTLLQTFEGHLDRLARVAFHPSGKYLGTTSY-----DKTWRLWDINTGAELLLQEG 379 Query: 341 QSNGLIDLDYFLPGGNEQYIITGSLSGNARIWNLRTHKCIRVIKG 475 S + + + G + L AR+W+LRT + I V +G Sbjct: 380 HSRSVYGIAFQQDGA---LAASCGLDSLARVWDLRTGRSILVFQG 421 Score = 34.7 bits (78), Expect = 0.26 Identities = 27/103 (26%), Positives = 48/103 (46%) Frame = +2 Query: 140 GLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLIL 319 G+ KLW+ + + HK + + F+P +D + A+A+ D AK+W L Sbjct: 277 GVTKLWEMPQVTNTIAVLKDHKERATDVVFSPVDDCL-----ATASADRTAKLWKTDGTL 331 Query: 320 PIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNARIWNLRT 448 + T + + L + F P G +Y+ T S R+W++ T Sbjct: 332 -LQTFEGHLDRLARV-AFHPSG--KYLGTTSYDKTWRLWDINT 370
>GBB_LOLFO (P23232) Guanine nucleotide-binding protein beta subunit| Length = 341 Score = 42.0 bits (97), Expect = 0.002 Identities = 23/87 (26%), Positives = 44/87 (50%) Frame = +2 Query: 47 EVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQ 226 ++ F H G + +L++ P + +SG C+ KL+D G C +TF H++ + A+ Sbjct: 177 QITSFGGHTGDVMSLSLAPDMRTFVSGACDAS-AKLFDIRDG-ICKQTFTGHESDINAIT 234 Query: 227 FNPQNDSVGRTTFASAALDGKAKIWDI 307 + P FA+ + D +++DI Sbjct: 235 YFPNG-----FAFATGSDDATCRLFDI 256
>KMHA_DICDI (P42527) Myosin heavy chain kinase A (EC 2.7.11.7) (MHCK A)| Length = 1146 Score = 42.0 bits (97), Expect = 0.002 Identities = 40/143 (27%), Positives = 65/143 (45%), Gaps = 1/143 (0%) Frame = +2 Query: 44 EEVKKFKA-HNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEA 220 +E+K F+ H +I+ LA+ S L SGG N +I +WD E + L H+ V + Sbjct: 985 KEIKSFEGVHTKYIKTLAL--SGRYLFSGG-NDQIIYVWDTET-LSMLFNMQGHEDWVLS 1040 Query: 221 LQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYI 400 L + S + D KIWD+S I TL N + ++Y+ Sbjct: 1041 LHCTA-------SYLFSTSKDNVIKIWDLSNFSCIDTLKGHWNSVSSCVV-----KDRYL 1088 Query: 401 ITGSLSGNARIWNLRTHKCIRVI 469 +GS + ++W+L T +C+ I Sbjct: 1089 YSGSEDNSIKVWDLDTLECVYTI 1111 Score = 40.4 bits (93), Expect = 0.005 Identities = 29/123 (23%), Positives = 49/123 (39%), Gaps = 3/123 (2%) Frame = +2 Query: 116 LLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQ---NDSVGRTTFASAALDG 286 LL G G +++D W CL T N H+ +E++ N S T G Sbjct: 883 LLCAGYGDGTYRVFDVNDNWKCLYTVNGHRKSIESIACNSNYIFTSSPDNTIKVHIIRSG 942 Query: 287 KAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNARIWNLRTHKCIRV 466 K + +L+ ++C NE+Y+ + S ++W+L T K I+ Sbjct: 943 NTKCIE-TLVGHTGEVNCVV------------ANEKYLFSCSYDKTIKVWDLSTFKEIKS 989 Query: 467 IKG 475 +G Sbjct: 990 FEG 992
>GBLP_CAEEL (Q21215) Guanine nucleotide-binding protein beta subunit 2-like 1| Length = 324 Score = 42.0 bits (97), Expect = 0.002 Identities = 37/146 (25%), Positives = 70/146 (47%), Gaps = 3/146 (2%) Frame = +2 Query: 68 HNGWIQALAVHPSL--PLLLSGGCNQGLIKLWDWEKGWTCLRTFN-AHKAKVEALQFNPQ 238 H W+ + PS P+++S G ++ ++K+W+ G L+T + H V + +P Sbjct: 152 HTDWVSTVRFSPSNRDPVIVSAGWDK-VVKVWNL--GNCRLKTNHIGHTGYVNTVTVSPD 208 Query: 239 NDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLS 418 + AS DG+A +WD++ + TL N +I+ F P +Y + ++ Sbjct: 209 G-----SLCASGGKDGQAMLWDLNEGKHLYTL--PGNDVINAMSFSP---NRYWLCAAVG 258 Query: 419 GNARIWNLRTHKCIRVIKGTSITSGA 496 + +IW+L K I +K +SG+ Sbjct: 259 SSIKIWDLEDKKEIEELKPEIASSGS 284
>WDR47_MOUSE (Q8CGF6) WD-repeat protein 47| Length = 920 Score = 42.0 bits (97), Expect = 0.002 Identities = 50/177 (28%), Positives = 71/177 (40%), Gaps = 5/177 (2%) Frame = +2 Query: 53 KKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRT-----FNAHKAKVE 217 K+ K H G I +A P LL +G N +K+ + TC T F+ H + Sbjct: 656 KRNKHHKGSIYCVAWSPCGQLLATGS-NDKYVKVLPFNAE-TCNATGPDLEFSMHDGTIR 713 Query: 218 ALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQY 397 L F +S G ++ A D D + L + ++ L Y G Sbjct: 714 DLAFMEGPESGGAILISAGAGDCNIYTTDCQRGQGLHALSGHTGHILAL-YTWSGW---M 769 Query: 398 IITGSLSGNARIWNLRTHKCIRVIKGTSITSGAGCSVRVVYCSPDPPLLIRTFEDDS 568 I +GS R W+LR C+RV+ GT+ G G +V V P LL ED S Sbjct: 770 IASGSQDKTVRFWDLRVPSCVRVV-GTTF-HGTGSAVASVAVDPSGRLLATGQEDSS 824
>PRP46_KLULA (Q6CKE8) Pre-mRNA-splicing factor PRP46 (Pre-mRNA-processing| protein 46) Length = 434 Score = 42.0 bits (97), Expect = 0.002 Identities = 40/175 (22%), Positives = 66/175 (37%) Frame = +2 Query: 53 KKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFN 232 K H GW++ + V P + G N IK+WD G + T H V + + Sbjct: 116 KVINGHTGWVRCVCVDPVDNEWFATGSNDTTIKIWDLAAGKLKI-TLIGHVMSVRDIAIS 174 Query: 233 PQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGS 412 ++ + SA+ D K WD+ I +G+ +D + I T Sbjct: 175 KRHPYM-----FSASEDKLVKCWDLERNTAIRDFHGHLSGVHTVDVH---PSLDIIATAG 226 Query: 413 LSGNARIWNLRTHKCIRVIKGTSITSGAGCSVRVVYCSPDPPLLIRTFEDDSLGL 577 R+W++R+ I V+ G + V C P P +I D ++ L Sbjct: 227 RDAVVRLWDIRSRSEIMVLPGHK------SPINKVKCLPVDPQIISCSGDATVRL 275
>APAF_HUMAN (O14727) Apoptotic protease-activating factor 1 (Apaf-1)| Length = 1248 Score = 41.6 bits (96), Expect = 0.002 Identities = 41/140 (29%), Positives = 63/140 (45%), Gaps = 4/140 (2%) Frame = +2 Query: 140 GLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLIL 319 G +K+W+ G + F H+ V L + +D+ T F+S + D AKIW L+L Sbjct: 1065 GTVKVWNIITG-NKEKDFVCHQGTV--LSCDISHDA---TKFSSTSADKTAKIWSFDLLL 1118 Query: 320 PIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNARIWNLRT----HKCIRVIKGTSIT 487 P+ L NG + F + + TG +G RIWN+ H C + + + T Sbjct: 1119 PLHELR-GHNGCVRCSAF--SVDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAAT 1175 Query: 488 SGAGCSVRVVYCSPDPPLLI 547 G V + SPD +LI Sbjct: 1176 HGGW--VTDLCFSPDGKMLI 1193 Score = 35.8 bits (81), Expect = 0.12 Identities = 21/64 (32%), Positives = 30/64 (46%) Frame = +2 Query: 113 LLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKA 292 LLL+ G + +KLWD + C T H V +F+P + AS + DG Sbjct: 714 LLLATGSSDCFLKLWDLNQK-ECRNTMFGHTNSVNHCRFSPDD-----KLLASCSADGTL 767 Query: 293 KIWD 304 K+WD Sbjct: 768 KLWD 771
>STRN_MOUSE (O55106) Striatin| Length = 780 Score = 41.2 bits (95), Expect = 0.003 Identities = 39/203 (19%), Positives = 82/203 (40%), Gaps = 10/203 (4%) Frame = +2 Query: 14 PPAXCKTLGLEEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTF 193 P +L +E + F+AH G + + + + SGG + ++ W + + Sbjct: 497 PAKKSTSLDVEPIYTFRAHKGPVLCVVMSSNGEQCYSGGTDG---RIQSWSTTNPNVDPY 553 Query: 194 NAHKAKVEALQFNPQNDSVGRTTFASA-------ALDGKAKIWDISLILPIATL--DCQS 346 +A+ V D+V +++A + DG ++W+ + + P ++ D Q Sbjct: 554 DAYDPSVLRGPLLGHTDAVWGLAYSAAHQRLLSCSADGTLRLWNTTEVAPALSVFNDNQE 613 Query: 347 NGLIDLDYFLPGGNEQYIITGSLSGNARIWNLRTHKCIRVIK-GTSITSGAGCSVRVVYC 523 G I L + +++ G I+N+ T + + ++ TS + C + V Sbjct: 614 LG-IPASVDLVSSDPSHMVASFSKGYTSIFNMETQQRVLTLESNVDSTSSSSCQINRVIS 672 Query: 524 SPDPPLLIRTFEDDSLGLCNSTT 592 P P+ I ED + ++ T Sbjct: 673 HPTLPISITAHEDRHIKFYDNNT 695 Score = 36.6 bits (83), Expect = 0.068 Identities = 28/83 (33%), Positives = 42/83 (50%), Gaps = 4/83 (4%) Frame = +2 Query: 65 AHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEA----LQFN 232 AH + +LAV P+ L L G + I+LW+ E TC++ F AH+ K E + F+ Sbjct: 704 AHLEAVTSLAVDPN-GLYLMSGSHDCSIRLWNLESK-TCIQEFTAHRKKFEESIHDVAFH 761 Query: 233 PQNDSVGRTTFASAALDGKAKIW 301 P + ASA D AK++ Sbjct: 762 P-----SKCYIASAGADALAKVF 779
>BRWD1_MOUSE (Q921C3) Bromodomain and WD-repeat domain-containing protein 1| (WD-repeat protein 9) Length = 2304 Score = 41.2 bits (95), Expect = 0.003 Identities = 23/104 (22%), Positives = 45/104 (43%), Gaps = 1/104 (0%) Frame = +2 Query: 128 GCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDI 307 G + L+K+W G L T H A++ + N +N T A+ + D ++W + Sbjct: 204 GSDDCLVKIWSTHNG-RLLSTLRGHSAEISDMAVNYEN-----TLIAAGSCDKVIRVWCL 257 Query: 308 SLILPIATLDCQSNGLIDLDYF-LPGGNEQYIITGSLSGNARIW 436 P+A L + + L + + G ++Y+++ G W Sbjct: 258 RTCAPVAVLQGHTGSITSLQFSPMAKGPQRYMVSTGADGTVCFW 301
>PK1IP_CHICK (Q5ZKU8) p21-activated protein kinase-interacting protein 1-like| (PAK1-interacting protein 1-like) Length = 369 Score = 41.2 bits (95), Expect = 0.003 Identities = 22/56 (39%), Positives = 30/56 (53%) Frame = +2 Query: 68 HNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNP 235 HNG I L + + LL G GLI +W+ K W CL++ AHK V +L +P Sbjct: 74 HNGTITCLEFYGTAHLL--SGAEDGLICIWN-TKRWECLKSIKAHKGHVTSLSIHP 126 Score = 33.1 bits (74), Expect = 0.75 Identities = 17/43 (39%), Positives = 27/43 (62%) Frame = +2 Query: 44 EEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKG 172 E +K KAH G + +L++HPS L LS G ++ L + W+ +G Sbjct: 107 ECLKSIKAHKGHVTSLSIHPSGKLALSVGTDKTL-RTWNLVEG 148 Score = 29.6 bits (65), Expect = 8.3 Identities = 21/95 (22%), Positives = 43/95 (45%) Frame = +2 Query: 188 TFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLD 367 T +AH A + A+ N + G + D + K+ +L+ T+ C L+ Sbjct: 30 THHAHTASLSAVAVNSKYVVTGSRDESIQIYDMRKKVEHGALLQHNGTITC-------LE 82 Query: 368 YFLPGGNEQYIITGSLSGNARIWNLRTHKCIRVIK 472 ++ ++++G+ G IWN + +C++ IK Sbjct: 83 FY----GTAHLLSGAEDGLICIWNTKRWECLKSIK 113
>PRW1_SCHPO (O14021) RbAp48-related WD40-repeat protein prw1| Length = 431 Score = 41.2 bits (95), Expect = 0.003 Identities = 24/84 (28%), Positives = 39/84 (46%) Frame = +2 Query: 65 AHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQND 244 AH+G I ++A +P +L+ I LWD L T H+ V + F+P + Sbjct: 279 AHSGPIHSVAFNPHNDFILATCSTDKTIALWDLRNLNQRLHTLEGHEDIVTKISFSPHEE 338 Query: 245 SVGRTTFASAALDGKAKIWDISLI 316 + AS + D + +WD+S I Sbjct: 339 PI----LASTSADRRTLVWDLSRI 358 Score = 29.6 bits (65), Expect = 8.3 Identities = 12/41 (29%), Positives = 22/41 (53%) Frame = +2 Query: 185 RTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDI 307 R+ +AH + ++ FNP ND + A+ + D +WD+ Sbjct: 275 RSVHAHSGPIHSVAFNPHNDFI----LATCSTDKTIALWDL 311
>PEX7_MOUSE (P97865) Peroxisomal targeting signal 2 receptor (PTS2 receptor)| (Peroxin-7) Length = 318 Score = 41.2 bits (95), Expect = 0.003 Identities = 30/111 (27%), Positives = 54/111 (48%) Frame = +2 Query: 113 LLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKA 292 L++SG +Q +K+WD G L TF H++ + + ++P FASA+ D Sbjct: 122 LVVSGSWDQ-TVKVWDPTVG-NSLCTFRGHESVIYSTIWSPHIPGC----FASASGDQTL 175 Query: 293 KIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNARIWNLR 445 +IWD+ + ++ D+ NE ++TG++ + R W+LR Sbjct: 176 RIWDVKTTGVRIVIPAHQTEILSCDWCKY--NENLVVTGAVDCSLRGWDLR 224
>PEX7_CRIGR (Q8R537) Peroxisomal targeting signal 2 receptor (PTS2 receptor)| (Peroxin-7) Length = 318 Score = 41.2 bits (95), Expect = 0.003 Identities = 30/111 (27%), Positives = 54/111 (48%) Frame = +2 Query: 113 LLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKA 292 L++SG +Q +K+WD G L TF H++ + + ++P FASA+ D Sbjct: 122 LVVSGSWDQ-TVKVWDPTVG-NSLCTFRGHESVIYSTIWSPHIPGC----FASASGDQTL 175 Query: 293 KIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNARIWNLR 445 +IWD+ + ++ D+ NE ++TG++ + R W+LR Sbjct: 176 RIWDVKTAGVRIVIPAHQTEILSCDWCKY--NENLVVTGAVDCSLRGWDLR 224
>PRP46_YEAST (Q12417) Pre-mRNA-splicing factor PRP46 (Pre-mRNA-processing| protein 46) (Complexed with CEF1 protein 1) (PRP19-associated complex protein 50) (PRP nineteen-associated complex protein 50) Length = 451 Score = 41.2 bits (95), Expect = 0.003 Identities = 21/86 (24%), Positives = 42/86 (48%) Frame = +2 Query: 50 VKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQF 229 ++ + H ++ +++HP+L L+ + G +IKLWD + T HK + +Q Sbjct: 217 IRDYYGHLSGVRTVSIHPTLDLIATAG-RDSVIKLWDMRTRIPVI-TLVGHKGPINQVQC 274 Query: 230 NPQNDSVGRTTFASAALDGKAKIWDI 307 P + V S++ D ++WD+ Sbjct: 275 TPVDPQV-----VSSSTDATVRLWDV 295 Score = 40.8 bits (94), Expect = 0.004 Identities = 40/193 (20%), Positives = 82/193 (42%), Gaps = 12/193 (6%) Frame = +2 Query: 80 IQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRT 259 ++ +AV P L S ++ +K WD EK +R + H + V + +P D + Sbjct: 185 VRDVAVSDRHPYLFSVSEDK-TVKCWDLEKN-QIIRDYYGHLSGVRTVSIHPTLDLI--- 239 Query: 260 TFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNARIWN 439 A+A D K+WD+ +P+ TL G I+ P + +++ S R+W+ Sbjct: 240 --ATAGRDSVIKLWDMRTRIPVITL-VGHKGPINQVQCTP--VDPQVVSSSTDATVRLWD 294 Query: 440 LRTHKCIRV-------IKGTSI-----TSGAGCSVRVVYCSPDPPLLIRTFEDDSLGLCN 583 + K ++V ++ T++ + + C+ + L+ FE + G+ N Sbjct: 295 VVAGKTMKVLTHHKRSVRATALHPKEFSVASACTDDIRSWGLAEGSLLTNFESEKTGIIN 354 Query: 584 STTFRYTNTIDFG 622 + + + + G Sbjct: 355 TLSINQDDVLFAG 367 Score = 30.4 bits (67), Expect = 4.9 Identities = 32/145 (22%), Positives = 53/145 (36%) Frame = +2 Query: 158 DWEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLD 337 +W W R N H V + +P V F + + D K+WD++ TL Sbjct: 124 EWHAPWKLSRVINGHLGWVRCVAIDP----VDNEWFITGSNDTTMKVWDLATGKLKTTL- 178 Query: 338 CQSNGLIDLDYFLPGGNEQYIITGSLSGNARIWNLRTHKCIRVIKGTSITSGAGCSVRVV 517 + ++ + Y+ + S + W+L ++ IR G SG VR V Sbjct: 179 --AGHVMTVRDVAVSDRHPYLFSVSEDKTVKCWDLEKNQIIRDYYGH--LSG----VRTV 230 Query: 518 YCSPDPPLLIRTFEDDSLGLCNSTT 592 P L+ D + L + T Sbjct: 231 SIHPTLDLIATAGRDSVIKLWDMRT 255
>WDR24_MOUSE (Q8CFJ9) WD-repeat protein 24| Length = 790 Score = 41.2 bits (95), Expect = 0.003 Identities = 32/142 (22%), Positives = 61/142 (42%), Gaps = 5/142 (3%) Frame = +2 Query: 59 FKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQ 238 F H + + HP+ +L G G +K +D + + TF+ V +QF+ + Sbjct: 116 FTEHKRTVNKVCFHPTEAHVLLSGSQDGFMKCFDLRRK-DSVSTFSGQSESVRDVQFSIR 174 Query: 239 NDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLS 418 + TFAS +G ++WDI + NG + + P + ++ TG Sbjct: 175 D----YFTFASTFENGNVQLWDIRRPDRCERMFTAHNGPVFCCDWHP-EDRGWLATGGRD 229 Query: 419 GNARIWNLRTHK-----CIRVI 469 ++W++ TH+ C++ I Sbjct: 230 KMVKVWDMTTHRAKEIHCVQTI 251
>PK1IP_BRARE (Q6TNS2) p21-activated protein kinase-interacting protein 1-like| (PAK1-interacting protein 1-like) Length = 368 Score = 40.8 bits (94), Expect = 0.004 Identities = 24/56 (42%), Positives = 33/56 (58%) Frame = +2 Query: 68 HNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNP 235 H+G I L + + LL SGG GLI +W +K W CL+T AHK +V +L +P Sbjct: 86 HDGTISCLEFYGTSHLL-SGG-QDGLICVWSTKK-WECLKTIRAHKGQVTSLSVHP 138 Score = 36.6 bits (83), Expect = 0.068 Identities = 36/142 (25%), Positives = 63/142 (44%), Gaps = 3/142 (2%) Frame = +2 Query: 44 EEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEAL 223 E +K +AH G + +L+VHPS L LS G ++ L + W+ +G + K E + Sbjct: 119 ECLKTIRAHKGQVTSLSVHPSGKLALSVGTDKTL-RTWNLIEGRSAF--IKNIKQNAEIV 175 Query: 224 QFNPQNDS---VGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQ 394 ++P D V LD I I+ I+ L N L+ + GG+++ Sbjct: 176 LWSPDGDKYAVVVNDKVDIYTLDSATIIGTIAFTKRISCLKFLKNSLLAV-----GGDDE 230 Query: 395 YIITGSLSGNARIWNLRTHKCI 460 + RI+++ + KC+ Sbjct: 231 ---------SVRIYDVTSQKCV 243
>APAF_RAT (Q9EPV5) Apoptotic protease-activating factor 1 (Apaf-1)| Length = 1249 Score = 40.8 bits (94), Expect = 0.004 Identities = 22/65 (33%), Positives = 32/65 (49%) Frame = +2 Query: 113 LLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKA 292 LLL+ G N +KLWD + C T H V +F+P ++ AS + DG Sbjct: 714 LLLATGSNDSFLKLWDLNQK-ECRNTMFGHTNSVTHCRFSPDDE-----LLASCSADGTL 767 Query: 293 KIWDI 307 K+WD+ Sbjct: 768 KLWDV 772 Score = 35.4 bits (80), Expect = 0.15 Identities = 33/134 (24%), Positives = 56/134 (41%), Gaps = 2/134 (1%) Frame = +2 Query: 182 LRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLID 361 L AH+ +V F+ + + A+ ++D K KIWD + T + S ++ Sbjct: 650 LLDIKAHEDEVLCCAFSSDDSYI-----ATCSVDKKVKIWDSGTGKLVHTYEEHSEQ-VN 703 Query: 362 LDYFLPGGNEQYIITGSLSGNARIWNLRTHKCIRVIKGTSITSGAGCSVRVVYC--SPDP 535 +F N + TGS ++W+L +C + G + + V +C SPD Sbjct: 704 CCHFTNKSNHLLLATGSNDSFLKLWDLNQKECRNTMFGHTNS--------VTHCRFSPDD 755 Query: 536 PLLIRTFEDDSLGL 577 LL D +L L Sbjct: 756 ELLASCSADGTLKL 769
>FIE1_MAIZE (Q8VZY7) Polycomb group protein FIE1 (FERTILIZATION-INDEPENDENT| ENDOSPERM 1) Length = 461 Score = 40.8 bits (94), Expect = 0.004 Identities = 28/97 (28%), Positives = 41/97 (42%), Gaps = 3/97 (3%) Frame = +2 Query: 26 CKTLGLEEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTF---N 196 C T L+ K H G I + H S P L+ I+LW+ G C+ F Sbjct: 178 CATEKLD--KSLVGHGGSIHEIRTHASKPSLIISASKDESIRLWNVHTG-ICILVFAGAG 234 Query: 197 AHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDI 307 H+ V ++ F+P + FAS +D KIW + Sbjct: 235 GHRHDVLSVDFHPTEVGI----FASCGMDNTVKIWSM 267
>STRN3_HUMAN (Q13033) Striatin-3 (Cell-cycle autoantigen SG2NA) (S/G2 antigen)| Length = 797 Score = 40.4 bits (93), Expect = 0.005 Identities = 45/203 (22%), Positives = 86/203 (42%), Gaps = 10/203 (4%) Frame = +2 Query: 14 PPAXCKTLGLEEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTF 193 P +L +E + F+AH G + +LA+ + SGG + + W W + + Sbjct: 514 PAKKSASLDVEPIYTFRAHIGPVLSLAISSNGEQCFSGGIDATI--QW-WNMPSPSVDPY 570 Query: 194 NAHKAKVEALQFNPQNDSVGRTTFA-------SAALDGKAKIWDISLILP-IATLDCQSN 349 + ++ V A D+V ++ S + DG ++W+ LP I T + Sbjct: 571 DTYEPNVLAGTLVGHTDAVWGLAYSGIKNQLLSCSADGTVRLWNPQEKLPCICTYNGDKK 630 Query: 350 GLIDLDYFLPGGNEQYIITGSLSGNARIWNLRTHKCIRVIKGTSITSG--AGCSVRVVYC 523 I G + +++T +G+A I++L T + + VI + + SG + + V Sbjct: 631 HGIPTSVDFIGCDPAHMVTSFNTGSAVIYDLETSQSL-VILSSQVDSGLQSNNHINRVVS 689 Query: 524 SPDPPLLIRTFEDDSLGLCNSTT 592 P P+ I ED + ++ T Sbjct: 690 HPTLPVTITAHEDRHIKFFDNKT 712 Score = 32.3 bits (72), Expect = 1.3 Identities = 45/191 (23%), Positives = 76/191 (39%), Gaps = 22/191 (11%) Frame = +2 Query: 62 KAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTC----------LRTFNAHKAK 211 ++H ++ALA HP P+L++ +KLW+ +K + TF AH Sbjct: 477 RSHFDGVRALAFHPVEPVLVTAS-EDHTLKLWNLQKTVPAKKSASLDVEPIYTFRAHIGP 535 Query: 212 VEALQFNPQNDSVGRTTFASAALDGKAKIWDI-----------SLILPIATLDCQSNGLI 358 V +L + S G F S +D + W++ + TL ++ + Sbjct: 536 VLSLAIS----SNGEQCF-SGGIDATIQWWNMPSPSVDPYDTYEPNVLAGTLVGHTDAVW 590 Query: 359 DLDYFLPGGNEQYIITGSLSGNARIWNLRTH-KCIRVIKGTSITSGAGCSVRVVYCSPDP 535 L Y G + +++ S G R+WN + CI G G SV + C DP Sbjct: 591 GLAY---SGIKNQLLSCSADGTVRLWNPQEKLPCICTYNGDK-KHGIPTSVDFIGC--DP 644 Query: 536 PLLIRTFEDDS 568 ++ +F S Sbjct: 645 AHMVTSFNTGS 655
>PEX7_HUMAN (O00628) Peroxisomal targeting signal 2 receptor (PTS2 receptor)| (Peroxin-7) Length = 323 Score = 40.4 bits (93), Expect = 0.005 Identities = 31/111 (27%), Positives = 55/111 (49%) Frame = +2 Query: 113 LLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKA 292 L++SG +Q +KLWD G + L TF H++ + + ++P FASA+ D Sbjct: 127 LVVSGSWDQ-TVKLWDPTVGKS-LCTFRGHESIIYSTIWSPHIPGC----FASASGDQTL 180 Query: 293 KIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNARIWNLR 445 +IWD+ + ++ D+ NE ++TG++ + R W+LR Sbjct: 181 RIWDVKAAGVRIVIPAHQAEILSCDWCKY--NENLLVTGAVDCSLRGWDLR 229
>STRN4_HUMAN (Q9NRL3) Striatin-4 (Zinedin)| Length = 753 Score = 40.4 bits (93), Expect = 0.005 Identities = 42/198 (21%), Positives = 73/198 (36%), Gaps = 12/198 (6%) Frame = +2 Query: 35 LGLEEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLW----------DWEKGWTCL 184 L +E + F+AH G + A+A+ + SGG + I W D Sbjct: 479 LDVEPIHAFRAHRGPVLAVAMGSNSEYCYSGGAD-ACIHSWKIPDLSMDPYDGYDPSVLS 537 Query: 185 RTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILP--IATLDCQSNGLI 358 H V L F+P + + AS + DG +IWD S P + T S + Sbjct: 538 HVLEGHGDAVWGLAFSPTSQRL-----ASCSADGTVRIWDPSSSSPACLCTFPTASEHGV 592 Query: 359 DLDYFLPGGNEQYIITGSLSGNARIWNLRTHKCIRVIKGTSITSGAGCSVRVVYCSPDPP 538 +I+ SG+ ++++ + ++ S S + V P+ P Sbjct: 593 PTSVAFTSTEPAHIVASFRSGDTVLYDMEVGSALLTLE--SRGSSGPTQINQVVSHPNQP 650 Query: 539 LLIRTFEDDSLGLCNSTT 592 L I +D + ++ T Sbjct: 651 LTITAHDDRGIRFLDNRT 668
>KI21A_HUMAN (Q7Z4S6) Kinesin family member 21A (Kinesin-like protein KIF2)| (NY-REN-62 antigen) Length = 1674 Score = 40.4 bits (93), Expect = 0.005 Identities = 25/79 (31%), Positives = 39/79 (49%) Frame = +2 Query: 65 AHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQND 244 AH W+ AL V P P+LLS GC G++K+W+ + + + H + + A+ Sbjct: 1582 AHKDWVCALGVVPDHPVLLS-GCRGGILKVWNMDT-FMPVGEMKGHDSPINAI------- 1632 Query: 245 SVGRTTFASAALDGKAKIW 301 V T +AA D +IW Sbjct: 1633 CVNSTHIFTAADDRTVRIW 1651
>TUP1_KLULA (P56094) Transcriptional repressor TUP1| Length = 682 Score = 40.4 bits (93), Expect = 0.005 Identities = 23/64 (35%), Positives = 33/64 (51%) Frame = +2 Query: 266 ASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNARIWNLR 445 A+ A D +IWD+ + TL + LDYF P GN+ +++GS RIW+L Sbjct: 422 ATGAEDKLIRIWDLETKKIVMTLKGHEQDIYSLDYF-PSGNK--LVSGSGDRTVRIWDLT 478 Query: 446 THKC 457 T C Sbjct: 479 TGTC 482 Score = 34.3 bits (77), Expect = 0.34 Identities = 28/142 (19%), Positives = 61/142 (42%), Gaps = 10/142 (7%) Frame = +2 Query: 80 IQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFN------AHKAKVEALQFNPQN 241 + +AV P ++ G +++WD + G+ R + H+ V ++ F Sbjct: 492 VTTVAVSPGEGKFIAAGSLDRTVRVWDSDTGFLVERLDSENELGTGHRDSVYSVVFTRDG 551 Query: 242 DSVGRTTFASAALDGKAKIWDIS-LILPIATLDCQSNGLIDLDYFLPGG---NEQYIITG 409 V S +LD K+W+++ L + +C+ D+ L N++YI++G Sbjct: 552 KGV-----VSGSLDRSVKLWNLNGLSGQKSHAECEVTYTGHKDFVLSVATTQNDEYILSG 606 Query: 410 SLSGNARIWNLRTHKCIRVIKG 475 S W+ ++ + +++G Sbjct: 607 SKDRGVLFWDTKSGNPLLMLQG 628
>PK1IP_HUMAN (Q9NWT1) p21-activated protein kinase-interacting protein 1| (PAK1-interacting protein 1) (PAK/PLC-interacting protein 1) (hPIP1) Length = 392 Score = 40.0 bits (92), Expect = 0.006 Identities = 21/56 (37%), Positives = 31/56 (55%) Frame = +2 Query: 68 HNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNP 235 H+G I L + + L+ G GLI +WD +K W CL++ AHK +V L +P Sbjct: 81 HSGTITCLKFYGNRHLI--SGAEDGLICIWDAKK-WECLKSIKAHKGQVTFLSIHP 133 Score = 32.0 bits (71), Expect = 1.7 Identities = 17/43 (39%), Positives = 26/43 (60%) Frame = +2 Query: 44 EEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKG 172 E +K KAH G + L++HPS L LS G ++ L + W+ +G Sbjct: 114 ECLKSIKAHKGQVTFLSIHPSGKLALSVGTDKTL-RTWNLVEG 155 Score = 30.8 bits (68), Expect = 3.7 Identities = 27/102 (26%), Positives = 47/102 (46%), Gaps = 2/102 (1%) Frame = +2 Query: 173 WTCLRTF--NAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQS 346 WT + F +AH A + A+ N + G D K KI +L+ T+ C Sbjct: 30 WTLVADFTHHAHTASLSAVAVNSRFVVTGSKDETIHIYDMKKKIEHGALVHHSGTITC-- 87 Query: 347 NGLIDLDYFLPGGNEQYIITGSLSGNARIWNLRTHKCIRVIK 472 L ++ GN +++I+G+ G IW+ + +C++ IK Sbjct: 88 -----LKFY---GN-RHLISGAEDGLICIWDAKKWECLKSIK 120
>NUP43_HUMAN (Q8NFH3) Nucleoporin Nup43 (p42)| Length = 380 Score = 40.0 bits (92), Expect = 0.006 Identities = 36/161 (22%), Positives = 61/161 (37%) Frame = +2 Query: 98 HPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAA 277 HP+ +++ G G++ +WD +G + AH+A++ + F+P N + + Sbjct: 226 HPNQQHVVATGGQDGMLSIWDVRQGTMPVSLLKAHEAEMWEVHFHPSNPE----HLFTCS 281 Query: 278 LDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNARIWNLRTHKC 457 DG WD S +P + F GG ++ S+S A + Sbjct: 282 EDGSLWHWDASTDVPEKS-----------SLFHQGGRSSTFLSHSISNQANVHQ------ 324 Query: 458 IRVIKGTSITSGAGCSVRVVYCSPDPPLLIRTFEDDSLGLC 580 VI T A + + P L + T D LG C Sbjct: 325 -SVISSWLSTDPAKDRIEITSLLPSRSLSVNTL--DVLGPC 362
>CDH1_YEAST (P53197) APC/C activator protein CDH1 (CDC20 homolog 1) (Homolog of| CDC twenty 1) Length = 566 Score = 40.0 bits (92), Expect = 0.006 Identities = 35/141 (24%), Positives = 63/141 (44%), Gaps = 14/141 (9%) Frame = +2 Query: 119 LSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKI 298 L+ G N ++ +++ L TF+ HKA V+A+ ++P V T +A D + KI Sbjct: 400 LASGGNDNVVHVYEGTSKSPIL-TFDEHKAAVKAMAWSPHKRGVLATGGGTA--DRRLKI 456 Query: 299 WDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNARIWNLRTHKCIRVIK-- 472 W+++ + ++ +D S I + NE G N +W+ + I ++K Sbjct: 457 WNVNTSIKMSDID--SGSQICNMVWSKNTNELVTSHGYSKYNLTLWDCNSMDPIAILKGH 514 Query: 473 ------------GTSITSGAG 499 GT++ SGAG Sbjct: 515 SFRVLHLTLSNDGTTVVSGAG 535
>TUP1_YEAST (P16649) Glucose repression regulatory protein TUP1 (Flocculation| suppressor protein) (Repressor AER2) Length = 713 Score = 39.7 bits (91), Expect = 0.008 Identities = 23/64 (35%), Positives = 34/64 (53%) Frame = +2 Query: 266 ASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNARIWNLR 445 A+ A D +IWDI + L + LDYF P G++ +++GS RIW+LR Sbjct: 459 ATGAEDRLIRIWDIENRKIVMILQGHEQDIYSLDYF-PSGDK--LVSGSGDRTVRIWDLR 515 Query: 446 THKC 457 T +C Sbjct: 516 TGQC 519 Score = 37.0 bits (84), Expect = 0.052 Identities = 28/110 (25%), Positives = 49/110 (44%) Frame = +2 Query: 119 LSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKI 298 L+ G LI++WD E + H+ + +L + P D + S + D +I Sbjct: 458 LATGAEDRLIRIWDIENR-KIVMILQGHEQDIYSLDYFPSGDKL-----VSGSGDRTVRI 511 Query: 299 WDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNARIWNLRT 448 WD+ TL + +G+ + + G+ +YI GSL R+W+ T Sbjct: 512 WDLRTGQCSLTLSIE-DGVTTVA--VSPGDGKYIAAGSLDRAVRVWDSET 558 Score = 36.6 bits (83), Expect = 0.068 Identities = 29/147 (19%), Positives = 60/147 (40%), Gaps = 15/147 (10%) Frame = +2 Query: 80 IQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLR------TFNAHKAKVEALQFNPQN 241 + +AV P ++ G +++WD E G+ R + HK V ++ F Sbjct: 529 VTTVAVSPGDGKYIAAGSLDRAVRVWDSETGFLVERLDSENESGTGHKDSVYSVVFTRDG 588 Query: 242 DSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYF---------LPGGNEQ 394 SV S +LD K+W++ + ++G ++ Y N++ Sbjct: 589 QSV-----VSGSLDRSVKLWNLQNANNKSDSKTPNSGTCEVTYIGHKDFVLSVATTQNDE 643 Query: 395 YIITGSLSGNARIWNLRTHKCIRVIKG 475 YI++GS W+ ++ + +++G Sbjct: 644 YILSGSKDRGVLFWDKKSGNPLLMLQG 670 Score = 34.7 bits (78), Expect = 0.26 Identities = 32/132 (24%), Positives = 60/132 (45%), Gaps = 4/132 (3%) Frame = +2 Query: 62 KAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQN 241 + H I +L PS L+SG ++ +++WD G C T + V + +P + Sbjct: 482 QGHEQDIYSLDYFPSGDKLVSGSGDR-TVRIWDLRTG-QCSLTLSIEDG-VTTVAVSPGD 538 Query: 242 DSVGRTTFASAALDGKAKIWDISLILPIATLDCQSN---GLIDLDYFLPGGNE-QYIITG 409 A+ +LD ++WD + LD ++ G D Y + + Q +++G Sbjct: 539 GKY----IAAGSLDRAVRVWDSETGFLVERLDSENESGTGHKDSVYSVVFTRDGQSVVSG 594 Query: 410 SLSGNARIWNLR 445 SL + ++WNL+ Sbjct: 595 SLDRSVKLWNLQ 606
>HAT2_GIBZE (Q4I7L0) Histone acetyltransferase type B subunit 2 (EC 2.3.1.48)| Length = 423 Score = 39.7 bits (91), Expect = 0.008 Identities = 30/121 (24%), Positives = 53/121 (43%) Frame = +2 Query: 62 KAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQN 241 + H I ALA +P+ +L++ I +WD + T H V +L ++P Sbjct: 270 RGHLDAINALAFNPNSEVLVATASADKTIGIWDLRNVKEKVHTLEGHNDAVTSLAWHPTE 329 Query: 242 DSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSG 421 + SA+ D + WD+S + D Q +G +L F+ GG+ ++ S + Sbjct: 330 AGI----LGSASYDRRIIFWDLSRVGEEQLPDDQDDGPPEL-LFMHGGHTNHLADFSWNP 384 Query: 422 N 424 N Sbjct: 385 N 385
>GBB2_BOVIN (P11017) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 2 (Transducin beta chain 2) (G protein beta 2 subunit) (Fragment) Length = 326 Score = 39.7 bits (91), Expect = 0.008 Identities = 23/83 (27%), Positives = 42/83 (50%) Frame = +2 Query: 59 FKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQ 238 F H+G + +L++ P +SG C+ IKLWD + C +TF H++ + A+ F P Sbjct: 166 FAGHSGDVMSLSLAPDGRTFVSGACDAS-IKLWD-VRDSMCRQTFIGHESDINAVAFFPN 223 Query: 239 NDSVGRTTFASAALDGKAKIWDI 307 F + + D +++D+ Sbjct: 224 G-----YAFTTGSDDATCRLFDL 241 Score = 34.7 bits (78), Expect = 0.26 Identities = 24/90 (26%), Positives = 41/90 (45%) Frame = +2 Query: 185 RTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDL 364 RT H AK+ A+ + + SA+ DGK IWD + + +S+ ++ Sbjct: 35 RTLRGHLAKIYAMHWGTDS-----RLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTC 89 Query: 365 DYFLPGGNEQYIITGSLSGNARIWNLRTHK 454 Y P GN ++ G L I++L+T + Sbjct: 90 AY-APSGN--FVACGGLDNICSIYSLKTRE 116
>SCON2_NEUCR (Q01277) Sulfur controller 2 (SCON2)| Length = 650 Score = 39.7 bits (91), Expect = 0.008 Identities = 47/215 (21%), Positives = 83/215 (38%), Gaps = 33/215 (15%) Frame = +2 Query: 44 EEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEAL 223 +E K H+ W+ + V + S + IKLWD + +RT+ H V+ + Sbjct: 404 KETYCLKGHSDWVNSTHVDIKSRTVFSAS-DDTTIKLWDLDTRQV-IRTYEGHVGHVQQV 461 Query: 224 QFNPQNDSVGRTTFASAALDGKAKI-----------WDISLILPIATLDCQSNGLIDLDY 370 P A+ D + + + I + S+ L Sbjct: 462 LILPPEYEPDEEVLNGASQDNQDAMSVSSGGSGSPSMSHAQIERAGSPGSHSSSHNLLPS 521 Query: 371 FLPGGNE--------------------QYIITGSLSGNARIWNLRTHKCIRVIKG--TSI 484 LP G+E +Y +TG L R+W+ T +C+R + G + Sbjct: 522 SLPSGDEDVRHLYGSAFVADESRPLPPRYFMTGGLDSTMRLWDSATGRCLRTLFGHLEGV 581 Query: 485 TSGAGCSVRVVYCSPDPPLLIRTFEDDSLGLCNST 589 S AG ++RV+ + D +++T+E S G C++T Sbjct: 582 WSLAGDTIRVISGANDG--MVKTWEPRS-GKCDAT 613 Score = 37.0 bits (84), Expect = 0.052 Identities = 26/102 (25%), Positives = 47/102 (46%) Frame = +2 Query: 155 WDWEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATL 334 ++W+ L H+ V LQ + D++ A+ + D KIW+I I TL Sbjct: 278 YNWKNSRYKLSVLKGHENGVTCLQLD---DNI----LATGSYDTTIKIWNIETEECIRTL 330 Query: 335 DCQSNGLIDLDYFLPGGNEQYIITGSLSGNARIWNLRTHKCI 460 + G+ L + ++ +I+GSL ++WN T +C+ Sbjct: 331 VGHTAGIRALQF-----DDSKLISGSLDHTIKVWNWHTGECL 367 Score = 31.2 bits (69), Expect = 2.8 Identities = 11/30 (36%), Positives = 18/30 (60%) Frame = +2 Query: 386 NEQYIITGSLSGNARIWNLRTHKCIRVIKG 475 ++ + TGS +IWN+ T +CIR + G Sbjct: 303 DDNILATGSYDTTIKIWNIETEECIRTLVG 332
>KI21A_MOUSE (Q9QXL2) Kinesin family member 21A| Length = 1672 Score = 39.7 bits (91), Expect = 0.008 Identities = 25/79 (31%), Positives = 39/79 (49%) Frame = +2 Query: 65 AHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQND 244 AH W+ AL + P P+LLS GC G++KLW+ + + + H + + A+ Sbjct: 1580 AHKDWVCALGLVPGHPVLLS-GCRGGILKLWNVDT-FVPVGEMRGHDSPINAI------- 1630 Query: 245 SVGRTTFASAALDGKAKIW 301 V T +AA D +IW Sbjct: 1631 CVNSTHVFTAADDRTVRIW 1649 Score = 34.7 bits (78), Expect = 0.26 Identities = 34/126 (26%), Positives = 49/126 (38%), Gaps = 3/126 (2%) Frame = +2 Query: 68 HNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDS 247 H I+ALA+ L SG + G IK WD + + NAHK V AL P Sbjct: 1540 HYDGIEALAIQGDN--LFSGSRDNG-IKKWDLAQKGLLQQVPNAHKDWVCALGLVP---- 1592 Query: 248 VGRTTFASAALDGKAKIWDISLILPIATL---DCQSNGLIDLDYFLPGGNEQYIITGSLS 418 G S G K+W++ +P+ + D N + N ++ T + Sbjct: 1593 -GHPVLLSGCRGGILKLWNVDTFVPVGEMRGHDSPINAIC--------VNSTHVFTAADD 1643 Query: 419 GNARIW 436 RIW Sbjct: 1644 RTVRIW 1649
>GBB2_RAT (P54313) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 2 (Transducin beta chain 2) (G protein beta 2 subunit) Length = 339 Score = 39.7 bits (91), Expect = 0.008 Identities = 23/83 (27%), Positives = 42/83 (50%) Frame = +2 Query: 59 FKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQ 238 F H+G + +L++ P +SG C+ IKLWD + C +TF H++ + A+ F P Sbjct: 179 FAGHSGDVMSLSLAPDGRTFVSGACDAS-IKLWD-VRDSMCRQTFIGHESDINAVAFFPN 236 Query: 239 NDSVGRTTFASAALDGKAKIWDI 307 F + + D +++D+ Sbjct: 237 G-----YAFTTGSDDATCRLFDL 254 Score = 34.7 bits (78), Expect = 0.26 Identities = 24/90 (26%), Positives = 41/90 (45%) Frame = +2 Query: 185 RTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDL 364 RT H AK+ A+ + + SA+ DGK IWD + + +S+ ++ Sbjct: 48 RTLRGHLAKIYAMHWGTDS-----RLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTC 102 Query: 365 DYFLPGGNEQYIITGSLSGNARIWNLRTHK 454 Y P GN ++ G L I++L+T + Sbjct: 103 AY-APSGN--FVACGGLDNICSIYSLKTRE 129
>GBB2_MOUSE (P62880) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 2 (Transducin beta chain 2) (G protein beta 2 subunit) Length = 339 Score = 39.7 bits (91), Expect = 0.008 Identities = 23/83 (27%), Positives = 42/83 (50%) Frame = +2 Query: 59 FKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQ 238 F H+G + +L++ P +SG C+ IKLWD + C +TF H++ + A+ F P Sbjct: 179 FAGHSGDVMSLSLAPDGRTFVSGACDAS-IKLWD-VRDSMCRQTFIGHESDINAVAFFPN 236 Query: 239 NDSVGRTTFASAALDGKAKIWDI 307 F + + D +++D+ Sbjct: 237 G-----YAFTTGSDDATCRLFDL 254 Score = 34.7 bits (78), Expect = 0.26 Identities = 24/90 (26%), Positives = 41/90 (45%) Frame = +2 Query: 185 RTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDL 364 RT H AK+ A+ + + SA+ DGK IWD + + +S+ ++ Sbjct: 48 RTLRGHLAKIYAMHWGTDS-----RLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTC 102 Query: 365 DYFLPGGNEQYIITGSLSGNARIWNLRTHK 454 Y P GN ++ G L I++L+T + Sbjct: 103 AY-APSGN--FVACGGLDNICSIYSLKTRE 129
>GBB2_HUMAN (P62879) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 2 (Transducin beta chain 2) (G protein beta 2 subunit) Length = 339 Score = 39.7 bits (91), Expect = 0.008 Identities = 23/83 (27%), Positives = 42/83 (50%) Frame = +2 Query: 59 FKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQ 238 F H+G + +L++ P +SG C+ IKLWD + C +TF H++ + A+ F P Sbjct: 179 FAGHSGDVMSLSLAPDGRTFVSGACDAS-IKLWD-VRDSMCRQTFIGHESDINAVAFFPN 236 Query: 239 NDSVGRTTFASAALDGKAKIWDI 307 F + + D +++D+ Sbjct: 237 G-----YAFTTGSDDATCRLFDL 254 Score = 34.7 bits (78), Expect = 0.26 Identities = 24/90 (26%), Positives = 41/90 (45%) Frame = +2 Query: 185 RTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDL 364 RT H AK+ A+ + + SA+ DGK IWD + + +S+ ++ Sbjct: 48 RTLRGHLAKIYAMHWGTDS-----RLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTC 102 Query: 365 DYFLPGGNEQYIITGSLSGNARIWNLRTHK 454 Y P GN ++ G L I++L+T + Sbjct: 103 AY-APSGN--FVACGGLDNICSIYSLKTRE 129
>WDR24_XENLA (Q7ZX22) WD-repeat protein 24| Length = 780 Score = 39.7 bits (91), Expect = 0.008 Identities = 32/146 (21%), Positives = 62/146 (42%) Frame = +2 Query: 59 FKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQ 238 F H + + HP+ +L G G +K +D K + TF+ V +QF+ + Sbjct: 111 FTEHKRTVNKVCFHPTEVYMLLSGSQDGYMKCFDLRKK-DSVSTFSGQSESVRDVQFSIR 169 Query: 239 NDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLS 418 + TFA+ +G ++WDI + NG + + P + ++ TG Sbjct: 170 D----YFTFAATFENGNVQLWDIRRPDRCERMFTAHNGPVFCCDWHP-EDRGWLATGGRD 224 Query: 419 GNARIWNLRTHKCIRVIKGTSITSGA 496 ++W++ T++ + +I S A Sbjct: 225 KMVKVWDMNTNRAKEIYCVQTIASVA 250 Score = 30.8 bits (68), Expect = 3.7 Identities = 26/101 (25%), Positives = 44/101 (43%), Gaps = 6/101 (5%) Frame = +2 Query: 53 KKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWE----KGWTCLRTFNAHKAKVEA 220 + F AHNG + HP L+ G ++K+WD K C++T A V Sbjct: 196 RMFTAHNGPVFCCDWHPEDRGWLATGGRDKMVKVWDMNTNRAKEIYCVQTI----ASVAR 251 Query: 221 LQFNPQND-SVGRTTFASAALDGKAKIWDISL-ILPIATLD 337 +++ P+ +G S +D +WD+ +P AT + Sbjct: 252 VKWRPERKYHIGT---CSMMVDHNIYVWDVRRPFIPFATFE 289
>SWD2_YEAST (P36104) COMPASS component SWD2 (Complex proteins associated with| SET1 protein SWD2) (Set1C component SWD2) Length = 329 Score = 39.7 bits (91), Expect = 0.008 Identities = 30/99 (30%), Positives = 43/99 (43%) Frame = +2 Query: 26 CKTLGLEEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHK 205 CK L KK+ H+ A+ H + S IK + E LR F+ H Sbjct: 59 CKFLDTIASKKYGCHS----AIFTHAQNECIYSSTMKNFDIKYLNLETN-QYLRYFSGHG 113 Query: 206 AKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILP 322 A V L+ NP ND TF S++ D ++WD+ + P Sbjct: 114 ALVNDLKMNPVND-----TFLSSSYDESVRLWDLKISKP 147
>WSB1_FUGRU (Q9W5Z5) WD repeat and SOCS box-containing protein 1 (WSB-1)| Length = 427 Score = 39.3 bits (90), Expect = 0.010 Identities = 25/65 (38%), Positives = 31/65 (47%) Frame = +2 Query: 113 LLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKA 292 LLL+ G N G IK+WD G T L H V L F P G SA+ D K Sbjct: 146 LLLATGLNNGRIKIWDVYTG-TLLLNLMDHTDIVRDLTFAPD----GSLMLVSASTDKKL 200 Query: 293 KIWDI 307 ++WD+ Sbjct: 201 RVWDL 205
>DDB2_HUMAN (Q92466) DNA damage-binding protein 2 (Damage-specific DNA-binding| protein 2) (DDB p48 subunit) (DDBb) (UV-damaged DNA-binding protein 2) (UV-DDB 2) Length = 427 Score = 39.3 bits (90), Expect = 0.010 Identities = 34/135 (25%), Positives = 63/135 (46%), Gaps = 12/135 (8%) Frame = +2 Query: 86 ALAVHPSLPLLLSGGCNQGLIKLWDW--EKGWTCLRTFNAHKAKVEALQFNPQNDSVGRT 259 +LA HP+ P ++ G G I LW++ + T ++ A + L+FNP N + Sbjct: 116 SLAWHPTHPSTVAVGSKGGDIMLWNFGIKDKPTFIKGIGA-GGSITGLKFNPLNTN---- 170 Query: 260 TFASAALDGKAKIWDI--SLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNA-- 427 F +++++G ++ D +++ A+ D + LD + + ++TG GN Sbjct: 171 QFYASSMEGTTRLQDFKGNILRVFASSDTINIWFCSLDV---SASSRMVVTGDNVGNVIL 227 Query: 428 ------RIWNLRTHK 454 +WNLR HK Sbjct: 228 LNMDGKELWNLRMHK 242
>POF11_SCHPO (Q09855) F-box/WD-repeat protein pof11| Length = 506 Score = 39.3 bits (90), Expect = 0.010 Identities = 44/176 (25%), Positives = 68/176 (38%), Gaps = 5/176 (2%) Frame = +2 Query: 56 KFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNP 235 K H+G + L LL+SG + +I +WDW+ L+ + H V + Sbjct: 256 KLYGHSGSVLCLDFCRRRNLLVSGSSDSTII-IWDWQNRRP-LKVYFGHTDNVLGVV--- 310 Query: 236 QNDSVGRTTFASAALDGKAKIWDISLILPI-ATLDCQSNGLIDLDYFLPGGNEQYIITGS 412 V S++ D A++W + P A + L ++ I+T S Sbjct: 311 ----VSENYIISSSRDHTARVWRLDATSPAEACMHVLRGHLASVNSVQYSSKTGLIVTAS 366 Query: 413 LSGNARIWNLRTHKCIRVIKGTSITSGAGCSVR----VVYCSPDPPLLIRTFEDDS 568 R W++ T CIR+I G C+ +V S D L IR FE S Sbjct: 367 SDRTLRTWDITTGHCIRIIHAHQ--RGIACAQYNGKFIVSGSSD--LTIRIFEASS 418
>WDR34_MOUSE (Q5U4F6) WD-repeat protein 34| Length = 535 Score = 39.3 bits (90), Expect = 0.010 Identities = 23/79 (29%), Positives = 35/79 (44%), Gaps = 5/79 (6%) Frame = +2 Query: 80 IQALAVHPSLPLLLSGGCNQGLIKLWDWEKG-----WTCLRTFNAHKAKVEALQFNPQND 244 + LA HP+ P ++GG G + +WD + W T + H V + + P+ Sbjct: 219 VMCLAFHPTQPSHIAGGLYSGEVLVWDMSRPEDPLLWRTGLTDDTHTDPVYQVLWLPEPR 278 Query: 245 SVGRTTFASAALDGKAKIW 301 R SAA DGK +W Sbjct: 279 HSHRFQVLSAATDGKVLLW 297
>PK1IP_MOUSE (Q9DCE5) p21-activated protein kinase-interacting protein 1| (PAK1-interacting protein 1) (Putative PAK inhibitor Skb15) Length = 382 Score = 39.3 bits (90), Expect = 0.010 Identities = 21/56 (37%), Positives = 28/56 (50%) Frame = +2 Query: 68 HNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNP 235 H G + L H + L+ G G I +WD K W CL+TF AH+ V L +P Sbjct: 81 HAGTVTCLKFHGNQHLI--SGAEDGHICIWD-VKRWKCLKTFKAHRGHVTFLSIHP 133 Score = 33.1 bits (74), Expect = 0.75 Identities = 17/41 (41%), Positives = 26/41 (63%) Frame = +2 Query: 50 VKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKG 172 +K FKAH G + L++HPS L LS G ++ L + W+ +G Sbjct: 116 LKTFKAHRGHVTFLSIHPSGKLALSVGTDKTL-RTWNLIEG 155 Score = 32.0 bits (71), Expect = 1.7 Identities = 24/105 (22%), Positives = 45/105 (42%), Gaps = 2/105 (1%) Frame = +2 Query: 164 EKGWTCLRTF--NAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLD 337 ++ WT + F ++H A + L N + G D K K+ +L+ T+ Sbjct: 27 QETWTPVADFTHHSHTASLSVLASNSRYVVSGSKDETIHIYDMKRKVEHGALVHHAGTVT 86 Query: 338 CQSNGLIDLDYFLPGGNEQYIITGSLSGNARIWNLRTHKCIRVIK 472 C L Q++I+G+ G+ IW+++ KC++ K Sbjct: 87 C-----------LKFHGNQHLISGAEDGHICIWDVKRWKCLKTFK 120
>GBB_CRYPA (O14435) Guanine nucleotide-binding protein beta subunit| Length = 359 Score = 39.3 bits (90), Expect = 0.010 Identities = 22/84 (26%), Positives = 41/84 (48%) Frame = +2 Query: 56 KFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNP 235 +F H G + +++++P+ G KLWD G ++TF H++ + A+QF P Sbjct: 196 EFADHLGDVMSISLNPTNQNTFISGACDAFAKLWDIRAG-KAVQTFAGHESDINAIQFFP 254 Query: 236 QNDSVGRTTFASAALDGKAKIWDI 307 S F + + D +++DI Sbjct: 255 DGHS-----FVTGSDDATCRLFDI 273 Score = 38.9 bits (89), Expect = 0.014 Identities = 27/90 (30%), Positives = 41/90 (45%) Frame = +2 Query: 185 RTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDL 364 RT H AK+ A+ + S R SA+ DGK IWD + + +S+ ++ Sbjct: 65 RTLKGHLAKIYAMHW-----STDRRHLVSASQDGKLIIWDAYTTNKVHAIPLRSSWVMTC 119 Query: 365 DYFLPGGNEQYIITGSLSGNARIWNLRTHK 454 Y P GN Y+ G L I+NL ++ Sbjct: 120 AY-APSGN--YVACGGLDNICSIYNLNQNR 146
>PRP19_CHICK (Q5ZMA2) Pre-mRNA-splicing factor 19 (PRP19/PSO4 homolog)| Length = 505 Score = 38.9 bits (89), Expect = 0.014 Identities = 35/161 (21%), Positives = 65/161 (40%), Gaps = 4/161 (2%) Frame = +2 Query: 2 VMGXPPAXCKTLGLEEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLW---DWEKG 172 + P A C V+ +AH G + L++H + LLS +Q W D + G Sbjct: 291 IWSVPNASC-------VQVVRAHEGSVTGLSLHATGDYLLSSSDDQ----YWAFSDIQTG 339 Query: 173 WTCLR-TFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSN 349 + T + + QF+P F + +D + KIWD+ +A S Sbjct: 340 RVLTKVTDESSGCALTCAQFHPDG-----LIFGTGTMDSQIKIWDLKERTNVANFPGHSG 394 Query: 350 GLIDLDYFLPGGNEQYIITGSLSGNARIWNLRTHKCIRVIK 472 + + + N Y+ T + + ++W+LR K + ++ Sbjct: 395 PITSIAF---SENGYYLATAADDSSVKLWDLRKLKNFKTLQ 432
>SEL10_CAEEL (Q93794) F-box/WD-repeat protein sel-10 (Suppressor/enhancer of| lin-12) (Sel-10 protein) Length = 587 Score = 38.9 bits (89), Expect = 0.014 Identities = 29/157 (18%), Positives = 56/157 (35%), Gaps = 2/157 (1%) Frame = +2 Query: 50 VKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEK--GWTCLRTFNAHKAKVEAL 223 ++ HN + +L ++ SG + I++WD+ + G C+ H + + Sbjct: 411 IRTLTGHNNRVYSLLFESERSIVCSGSLDTS-IRVWDFTRPEGQECVALLQGHTSLTSGM 469 Query: 224 QFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYII 403 Q S D ++WDI + L + + L +F + Sbjct: 470 QLRGN-------ILVSCNADSHVRVWDIHEGTCVHMLSGHRSAITSLQWF----GRNMVA 518 Query: 404 TGSLSGNARIWNLRTHKCIRVIKGTSITSGAGCSVRV 514 T S G ++W++ IR + GC R+ Sbjct: 519 TSSDDGTVKLWDIERGALIRDLVTLDSGGNGGCIWRL 555 Score = 37.4 bits (85), Expect = 0.040 Identities = 30/130 (23%), Positives = 62/130 (47%), Gaps = 5/130 (3%) Frame = +2 Query: 116 LLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAK 295 ++SGG + +K+W+ G C+RT H +V +L F + R+ S +LD + Sbjct: 391 VVSGGYDF-TVKIWNAHTG-RCIRTLTGHNNRVYSLLFESE-----RSIVCSGSLDTSIR 443 Query: 296 IWDISLILPIATLDCQSNGLIDLDYFLPGGNE---QYIITGSLSGNARIWNLRTHKCIRV 466 +WD + +C + L+ L G + +++ + + R+W++ C+ + Sbjct: 444 VWDFTRP---EGQECVA--LLQGHTSLTSGMQLRGNILVSCNADSHVRVWDIHEGTCVHM 498 Query: 467 IKG--TSITS 490 + G ++ITS Sbjct: 499 LSGHRSAITS 508 Score = 37.0 bits (84), Expect = 0.052 Identities = 33/166 (19%), Positives = 67/166 (40%), Gaps = 2/166 (1%) Frame = +2 Query: 68 HNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDS 247 H G + + ++SG ++ +K+W G + L T H + V + + Sbjct: 295 HTGGVWTSQISQCGRYIVSGSTDR-TVKVWSTVDG-SLLHTLQGHTSTVRCM-------A 345 Query: 248 VGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNA 427 + + + + D ++WD+ +ATL + + + + +++G Sbjct: 346 MAGSILVTGSRDTTLRVWDVESGRHLATLHGHHAAVRCVQF-----DGTTVVSGGYDFTV 400 Query: 428 RIWNLRTHKCIRVIKG--TSITSGAGCSVRVVYCSPDPPLLIRTFE 559 +IWN T +CIR + G + S S R + CS IR ++ Sbjct: 401 KIWNAHTGRCIRTLTGHNNRVYSLLFESERSIVCSGSLDTSIRVWD 446
>GBB2_TOBAC (P93398) Guanine nucleotide-binding protein beta subunit 2| Length = 377 Score = 38.9 bits (89), Expect = 0.014 Identities = 21/80 (26%), Positives = 36/80 (45%) Frame = +2 Query: 68 HNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDS 247 H +Q++++ S P L G +LWD RTF H+ V ++F P + Sbjct: 203 HTADVQSVSISSSNPRLFVSGSCDSTARLWDTRVASRAQRTFYGHEGDVNTVKFFPDGN- 261 Query: 248 VGRTTFASAALDGKAKIWDI 307 F + + DG +++DI Sbjct: 262 ----RFGTGSDDGTCRLFDI 277
>APAF_MOUSE (O88879) Apoptotic protease-activating factor 1 (Apaf-1)| Length = 1249 Score = 38.9 bits (89), Expect = 0.014 Identities = 21/65 (32%), Positives = 32/65 (49%) Frame = +2 Query: 113 LLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKA 292 LLL+ G N +KLWD + C T H V +F+P ++ AS + DG Sbjct: 714 LLLATGSNDFFLKLWDLNQK-ECRNTMFGHTNSVNHCRFSPDDE-----LLASCSADGTL 767 Query: 293 KIWDI 307 ++WD+ Sbjct: 768 RLWDV 772 Score = 35.8 bits (81), Expect = 0.12 Identities = 34/132 (25%), Positives = 54/132 (40%) Frame = +2 Query: 182 LRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLID 361 L AH+ +V F+ + + A+ + D K KIWD + + T D S ++ Sbjct: 650 LLDIKAHEDEVLCCAFSSDDSYI-----ATCSADKKVKIWDSATGKLVHTYDEHSEQ-VN 703 Query: 362 LDYFLPGGNEQYIITGSLSGNARIWNLRTHKCIRVIKGTSITSGAGCSVRVVYCSPDPPL 541 +F N + TGS ++W+L +C + G + SV SPD L Sbjct: 704 CCHFTNSSNHLLLATGSNDFFLKLWDLNQKECRNTMFGHT------NSVNHCRFSPDDEL 757 Query: 542 LIRTFEDDSLGL 577 L D +L L Sbjct: 758 LASCSADGTLRL 769
>WDR24_CHICK (Q5ZMV9) WD-repeat protein 24| Length = 705 Score = 38.9 bits (89), Expect = 0.014 Identities = 34/162 (20%), Positives = 66/162 (40%), Gaps = 6/162 (3%) Frame = +2 Query: 59 FKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQ 238 F H + + HP+ +L G G +K +D K + TF+ V +QF+ + Sbjct: 32 FTEHKRTVNKVCFHPTEVYMLLSGSQDGYMKCFDLRKK-DSVSTFSGQSESVRDVQFSIR 90 Query: 239 NDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLS 418 + TFA+ +G ++WDI + NG + + P + ++ TG Sbjct: 91 D----YFTFAATFENGNVQLWDIRRPDRYERMFTAHNGPVFCCDWHP-EDRGWLATGGRD 145 Query: 419 GNARIWNLRTHK-----CIRVIKGTS-ITSGAGCSVRVVYCS 526 ++W++ T + C++ I + + C + CS Sbjct: 146 KMVKVWDMNTTRAKEIYCVQTIASVARVKWRPECKHHIATCS 187
>WDR39_HUMAN (O76071) WD-repeat protein 39 (Ciao 1 protein)| Length = 339 Score = 38.9 bits (89), Expect = 0.014 Identities = 46/190 (24%), Positives = 70/190 (36%), Gaps = 3/190 (1%) Frame = +2 Query: 44 EEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEAL 223 E V +H ++ + HPS LL S + + + E W C T H++ V +L Sbjct: 141 ECVSVLNSHTQDVKHVVWHPSQELLASASYDDTVKLYREEEDDWVCCATLEGHESTVWSL 200 Query: 224 QFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYII 403 F+P + AS + D +IW +LP GNEQ + Sbjct: 201 AFDPSGQRL-----ASCSDDRTVRIW---------------------RQYLP-GNEQGV- 232 Query: 404 TGSLSGNARIWNLRTHKCIRVIKG---TSITSGAGCSVRVVYCSPDPPLLIRTFEDDSLG 574 + SG+ W KCI + G +I A C + + IR F++D Sbjct: 233 --ACSGSDPSW-----KCICTLSGFHSRTIYDIAWCQLTGALATACGDDAIRVFQEDPNS 285 Query: 575 LCNSTTFRYT 604 TF T Sbjct: 286 DPQQPTFSLT 295
>TUP11_SCHPO (Q09715) Transcriptional repressor tup11| Length = 614 Score = 38.5 bits (88), Expect = 0.018 Identities = 51/220 (23%), Positives = 86/220 (39%), Gaps = 21/220 (9%) Frame = +2 Query: 29 KTLGLEEVKKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKA 208 K L E + + +++ +A P L++G IKLWD F+ H+ Sbjct: 346 KLFTLHEESPDPSRDLYVRTIAFSPDGKYLVTG-TEDRQIKLWDLSTQ-KVRYVFSGHEQ 403 Query: 209 KVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGN 388 + +L F+ + S + D A++WD+ I L+ + NG+ + N Sbjct: 404 DIYSLDFSHNGRFI-----VSGSGDRTARLWDVETGQCILKLEIE-NGVTAIAI---SPN 454 Query: 389 EQYIITGSLSGNARIWNLRTHKCIRVIKGTSI--TSGAGCSVRVVYCSPDPPLLIRTFED 562 +Q+I GSL R+W+ + GT + G SV + SPD +L+ D Sbjct: 455 DQFIAVGSLDQIIRVWS---------VSGTLVERLEGHKESVYSIAFSPDSSILLSGSLD 505 Query: 563 DSL-------------------GLCNSTTFRYTNTIDFGL 625 ++ G+C +T YT DF L Sbjct: 506 KTIKVWELQATRSVGLSAIKPEGICKAT---YTGHTDFVL 542 Score = 37.7 bits (86), Expect = 0.030 Identities = 31/105 (29%), Positives = 52/105 (49%), Gaps = 7/105 (6%) Frame = +2 Query: 29 KTLGLEEVKK-------FKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLR 187 +++GL +K + H ++ ++AV P LSG ++ + + WD + G + L Sbjct: 517 RSVGLSAIKPEGICKATYTGHTDFVLSVAVSPDSRWGLSGSKDRSM-QFWDLQTGQSYL- 574 Query: 188 TFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILP 322 T HK V ++ F+P GR FAS + D +A+IW I P Sbjct: 575 TCQGHKNSVISVCFSPD----GRQ-FASGSGDLRARIWSIDPASP 614 Score = 36.2 bits (82), Expect = 0.088 Identities = 29/122 (23%), Positives = 52/122 (42%), Gaps = 8/122 (6%) Frame = +2 Query: 119 LSGGCNQGLIKLWDWEKGWTCLRTFNAHKAK--------VEALQFNPQNDSVGRTTFASA 274 L+ GCNQ ++D + G + F H+ V + F+P + + Sbjct: 328 LATGCNQAA-NVFDVQTG---KKLFTLHEESPDPSRDLYVRTIAFSPDGKYL-----VTG 378 Query: 275 ALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNARIWNLRTHK 454 D + K+WD+S + LD+ N ++I++GS AR+W++ T + Sbjct: 379 TEDRQIKLWDLSTQKVRYVFSGHEQDIYSLDF---SHNGRFIVSGSGDRTARLWDVETGQ 435 Query: 455 CI 460 CI Sbjct: 436 CI 437
>YIRF_SCHPO (Q9P7I3) Hypothetical WD-repeat protein C664.15 in chromosome I| Length = 651 Score = 38.5 bits (88), Expect = 0.018 Identities = 19/68 (27%), Positives = 36/68 (52%) Frame = +2 Query: 266 ASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNEQYIITGSLSGNARIWNLR 445 AS +DG +IWD+ + LP+ + + + L + + ++ +GS + RIW+LR Sbjct: 510 ASGTVDGLIRIWDLRIGLPVRSFIGHTAPISSLQF-----DSNHLYSGSYDNSVRIWDLR 564 Query: 446 THKCIRVI 469 + I +I Sbjct: 565 SGSPINII 572 Score = 37.7 bits (86), Expect = 0.030 Identities = 23/87 (26%), Positives = 43/87 (49%) Frame = +2 Query: 182 LRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLID 361 ++ F AH + +L F+ T A+A+ D K+WD++ ++ + +L S+ + Sbjct: 325 VKQFQAHSEYITSLDFSHPFG-----TLATASTDKTVKVWDMAGVVYLGSLKGHSDYVSC 379 Query: 362 LDYFLPGGNEQYIITGSLSGNARIWNL 442 L + +I TGS+ R+WNL Sbjct: 380 LAI-----QDSFIATGSMDTTVRLWNL 401 Score = 36.6 bits (83), Expect = 0.068 Identities = 22/73 (30%), Positives = 35/73 (47%) Frame = +2 Query: 107 LPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDSVGRTTFASAALDG 286 L ++ G GLI++WD G +R+F H A + +LQF+ + S + D Sbjct: 505 LDAAVASGTVDGLIRIWDLRIGLP-VRSFIGHTAPISSLQFDSNH-------LYSGSYDN 556 Query: 287 KAKIWDISLILPI 325 +IWD+ PI Sbjct: 557 SVRIWDLRSGSPI 569
>TBL3_HUMAN (Q12788) WD-repeat protein SAZD (Transducin beta-like 3 protein)| Length = 519 Score = 38.5 bits (88), Expect = 0.018 Identities = 37/155 (23%), Positives = 61/155 (39%), Gaps = 21/155 (13%) Frame = +2 Query: 59 FKAHNGWIQALAVHPS-LPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNP 235 F+ G + +A HP LLL I++W + +CL AH + V +L F+ Sbjct: 33 FRGSPGVVHLVAFHPDPTRLLLFSSATDAAIRVWSLQDR-SCLAVLTAHYSAVTSLAFSA 91 Query: 236 QNDSVGRTTFASAALDGKAKIWDI-----------------SLILP---IATLDCQSNGL 355 T S+ D IWD+ +++LP ++ L +S GL Sbjct: 92 DGH-----TMLSSGRDKICIIWDLQSCQATRTVPVFESVEAAVLLPEEPVSQLGVKSPGL 146 Query: 356 IDLDYFLPGGNEQYIITGSLSGNARIWNLRTHKCI 460 YFL G++ G R+W + +C+ Sbjct: 147 ----YFLTAGDQ---------GTLRVWEAASGQCV 168 Score = 35.0 bits (79), Expect = 0.20 Identities = 17/53 (32%), Positives = 27/53 (50%) Frame = +2 Query: 386 NEQYIITGSLSGNARIWNLRTHKCIRVIKGTSITSGAGCSVRVVYCSPDPPLL 544 N++ + TGS A++W L + + V G + SGA S+ C P P L+ Sbjct: 376 NDKLLATGSQDRTAKLWALPQCQLLGVFSGHRVASGASSSLPWTRCWPRPQLM 428 Score = 32.0 bits (71), Expect = 1.7 Identities = 18/37 (48%), Positives = 24/37 (64%) Frame = +2 Query: 116 LLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQ 226 LLS G + GL+KLW + C+RT +AH+ KV LQ Sbjct: 464 LLSSG-SDGLVKLWTIKNN-ECVRTLDAHEDKVWGLQ 498
>GBB_NICPL (P93339) Guanine nucleotide-binding protein beta subunit (NpGPB1)| Length = 377 Score = 38.5 bits (88), Expect = 0.018 Identities = 21/80 (26%), Positives = 36/80 (45%) Frame = +2 Query: 68 HNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDS 247 H +Q++++ S P L G +LWD RTF H+ V ++F P + Sbjct: 203 HTADVQSVSISSSNPRLFVSGSCDTTARLWDTRVASRAQRTFYCHEGDVNTVKFFPDGN- 261 Query: 248 VGRTTFASAALDGKAKIWDI 307 F + + DG +++DI Sbjct: 262 ----RFGTGSEDGTCRLFDI 277
>GBB1_TOBAC (P93397) Guanine nucleotide-binding protein beta subunit 1| Length = 377 Score = 38.5 bits (88), Expect = 0.018 Identities = 21/80 (26%), Positives = 36/80 (45%) Frame = +2 Query: 68 HNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTFNAHKAKVEALQFNPQNDS 247 H +Q++++ S P L G +LWD RTF H+ V ++F P + Sbjct: 203 HTADVQSVSISSSNPRLFVSGSCDTTARLWDTRVASRAQRTFYGHEGDVNTVKFFPDGN- 261 Query: 248 VGRTTFASAALDGKAKIWDI 307 F + + DG +++DI Sbjct: 262 ----RFGTGSEDGTCRLFDI 277 Score = 38.1 bits (87), Expect = 0.023 Identities = 34/145 (23%), Positives = 56/145 (38%), Gaps = 7/145 (4%) Frame = +2 Query: 53 KKFKAHNGWIQALAVHPSLPLLLSGGCNQGLIKLWDWEKGWTCLRTF-------NAHKAK 211 + H G++ + P L LWD G LRT + H A Sbjct: 150 RMLSGHKGYVSSCQYVPDEDTHLITSSGDQTCVLWDITTG---LRTSVFGGEFQSGHTAD 206 Query: 212 VEALQFNPQNDSVGRTTFASAALDGKAKIWDISLILPIATLDCQSNGLIDLDYFLPGGNE 391 V+++ + N + F S + D A++WD + G ++ F P GN Sbjct: 207 VQSVSISSSNPRL----FVSGSCDTTARLWDTRVASRAQRTFYGHEGDVNTVKFFPDGNR 262 Query: 392 QYIITGSLSGNARIWNLRTHKCIRV 466 TGS G R++++RT ++V Sbjct: 263 --FGTGSEDGTCRLFDIRTEHQLQV 285 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 104,655,349 Number of Sequences: 219361 Number of extensions: 2265133 Number of successful extensions: 7510 Number of sequences better than 10.0: 429 Number of HSP's better than 10.0 without gapping: 6344 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 7151 length of database: 80,573,946 effective HSP length: 108 effective length of database: 56,882,958 effective search space used: 6257125380 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
