ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | basd12p14 |
|---|---|
| Clone Library Name | barley_pub |
>S12A7_HUMAN (Q9Y666) Solute carrier family 12 member 7 (Electroneutral| potassium-chloride cotransporter 4) (K-Cl cotransporter 4) Length = 1083 Score = 95.5 bits (236), Expect = 1e-19 Identities = 47/142 (33%), Positives = 82/142 (57%), Gaps = 1/142 (0%) Frame = +3 Query: 6 EGFRSIVQTMGLGNLKPNIVVVRYPEIWRRENLTEIPSTFVSIINDCIIANKAVVIVKGL 185 +G ++Q+ GLG LK N V++ +P W++E+ FV + D A++A+++ K + Sbjct: 772 DGMSHLIQSAGLGGLKHNTVLMAWPASWKQEDNPFSWKNFVDTVRDTTAAHQALLVAKNV 831 Query: 186 DEWPNEFQR-QYGTIDLYWIVRDGGXXXXXXXXXXTKATFESCKIQVFCIAEEDTDAAEL 362 D +P +R G ID++WIV DGG + C++++F +A+ D ++ ++ Sbjct: 832 DSFPQNQERFGGGHIDVWWIVHDGGMLMLLPFLLRQHKVWRKCRMRIFTVAQVDDNSIQM 891 Query: 363 KTDVKKFLYDLRMHAEVIVVTM 428 K D++ FLY LR+ AEV VV M Sbjct: 892 KKDLQMFLYHLRISAEVEVVEM 913
>S12A7_MOUSE (Q9WVL3) Solute carrier family 12 member 7 (Electroneutral| potassium-chloride cotransporter 4) (K-Cl cotransporter 4) Length = 1083 Score = 94.7 bits (234), Expect = 2e-19 Identities = 46/142 (32%), Positives = 81/142 (57%), Gaps = 1/142 (0%) Frame = +3 Query: 6 EGFRSIVQTMGLGNLKPNIVVVRYPEIWRRENLTEIPSTFVSIINDCIIANKAVVIVKGL 185 +G ++Q+ GLG +K N V++ +PE W+ + FV + D A++A+++ K + Sbjct: 772 DGASHLIQSAGLGGMKHNTVLMAWPEAWKEADNPFSWKNFVDTVRDTTAAHQALLVAKNI 831 Query: 186 DEWPNEFQR-QYGTIDLYWIVRDGGXXXXXXXXXXTKATFESCKIQVFCIAEEDTDAAEL 362 D +P +R G ID++WIV DGG + C++++F +A+ D ++ ++ Sbjct: 832 DLFPQNQERFSDGNIDVWWIVHDGGMLMLLPFLLRQHKVWRKCRMRIFTVAQVDDNSIQM 891 Query: 363 KTDVKKFLYDLRMHAEVIVVTM 428 K D++ FLY LR+ AEV VV M Sbjct: 892 KKDLQMFLYHLRISAEVEVVEM 913
>S12A6_HUMAN (Q9UHW9) Solute carrier family 12 member 6 (Electroneutral| potassium-chloride cotransporter 3) (K-Cl cotransporter 3) Length = 1150 Score = 90.9 bits (224), Expect = 3e-18 Identities = 56/203 (27%), Positives = 96/203 (47%), Gaps = 6/203 (2%) Frame = +3 Query: 6 EGFRSIVQTMGLGNLKPNIVVVRYPEIWRRENLTEIPSTFVSIINDCIIANKAVVIVKGL 185 EG ++Q+ GLG +K N VV+ +P WR+ TF+ + A+ A+++ K + Sbjct: 837 EGISHLIQSCGLGGMKHNTVVMGWPNGWRQSEDARAWKTFIGTVRVTTAAHLALLVAKNI 896 Query: 186 DEWPNEFQR-QYGTIDLYWIVRDGGXXXXXXXXXXTKATFESCKIQVFCIAEEDTDAAEL 362 +P+ ++ G ID++WIV DGG + C I++F +A+ + ++ ++ Sbjct: 897 SFFPSNVEQFSEGNIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSIRIFTVAQLEDNSIQM 956 Query: 363 KTDVKKFLYDLRMHAEVIVVTMKXXXXXXXXXXXXAQPDDSQEAYTSAQRRISAYLSEM- 539 K D+ FLY LR+ AEV VV M D AYT + + S+M Sbjct: 957 KKDLATFLYHLRIEAEVEVVEMH---------------DSDISAYTYERTLMMEQRSQML 1001 Query: 540 ----KETTEREGRPQMVDGKQAV 596 TER+ Q+V + ++ Sbjct: 1002 RHMRLSKTERDREAQLVKDRNSM 1024
>S12A4_RABIT (Q28677) Solute carrier family 12 member 4 (Electroneutral| potassium-chloride cotransporter 1) (Erythroid K-Cl cotransporter 1) (rbKCC1) Length = 1085 Score = 90.5 bits (223), Expect = 3e-18 Identities = 59/200 (29%), Positives = 98/200 (49%), Gaps = 4/200 (2%) Frame = +3 Query: 6 EGFRSIVQTMGLGNLKPNIVVVRYPEIWRRENLTEIPSTFVSIINDCIIANKAVVIVKGL 185 EG ++Q+ GLG ++ N VV+ +P WR+ TF+ + A+ A+++ K + Sbjct: 772 EGLAHLIQSCGLGGMRHNSVVLGWPYGWRQSEDPRAWKTFIDTVRCTTAAHLALLVPKNI 831 Query: 186 DEWPNEFQRQY-GTIDLYWIVRDGGXXXXXXXXXXTKATFESCKIQVFCIAEEDTDAAEL 362 +P+ +R G ID++WIV DGG + C++++F +A+ D ++ ++ Sbjct: 832 AFYPSNHERYLEGHIDVWWIVHDGGMLMLLPFLLRQHKVWRKCRMRIFTVAQMDDNSIQM 891 Query: 363 KTDVKKFLYDLRMHAEVIVVTMKXXXXXXXXXXXXAQPDDSQEAY--TSAQRRISAYLSE 536 K D+ FLY LR+ AEV VV M D S Y T + S L + Sbjct: 892 KKDLAVFLYHLRLEAEVEVVEMH-------------NSDISAYTYERTLMMEQRSQMLRQ 938 Query: 537 MKET-TEREGRPQMVDGKQA 593 M+ T TERE Q+V + + Sbjct: 939 MRLTKTEREREAQLVKDRHS 958
>S12A4_HUMAN (Q9UP95) Solute carrier family 12 member 4 (Electroneutral| potassium-chloride cotransporter 1) (Erythroid K-Cl cotransporter 1) (hKCC1) Length = 1085 Score = 90.5 bits (223), Expect = 3e-18 Identities = 59/200 (29%), Positives = 98/200 (49%), Gaps = 4/200 (2%) Frame = +3 Query: 6 EGFRSIVQTMGLGNLKPNIVVVRYPEIWRRENLTEIPSTFVSIINDCIIANKAVVIVKGL 185 EG ++Q+ GLG ++ N VV+ +P WR+ TF+ + A+ A+++ K + Sbjct: 772 EGLAHLIQSCGLGGMRHNSVVLGWPYGWRQSEDPRAWKTFIDTVRCTTAAHLALLVPKNI 831 Query: 186 DEWPNEFQRQY-GTIDLYWIVRDGGXXXXXXXXXXTKATFESCKIQVFCIAEEDTDAAEL 362 +P+ +R G ID++WIV DGG + C++++F +A+ D ++ ++ Sbjct: 832 AFYPSNHERYLEGHIDVWWIVHDGGMLMLLPFLLRQHKVWRKCRMRIFTVAQMDDNSIQM 891 Query: 363 KTDVKKFLYDLRMHAEVIVVTMKXXXXXXXXXXXXAQPDDSQEAY--TSAQRRISAYLSE 536 K D+ FLY LR+ AEV VV M D S Y T + S L + Sbjct: 892 KKDLAVFLYHLRLEAEVEVVEMH-------------NSDISAYTYERTLMMEQRSQMLRQ 938 Query: 537 MKET-TEREGRPQMVDGKQA 593 M+ T TERE Q+V + + Sbjct: 939 MRLTKTEREREAQLVKDRHS 958
>S12A4_RAT (Q63632) Solute carrier family 12 member 4 (Electroneutral| potassium-chloride cotransporter 1) (Erythroid K-Cl cotransporter 1) (rKCC1) (Furosemide-sensitive K-Cl cotransporter) Length = 1085 Score = 89.4 bits (220), Expect = 7e-18 Identities = 58/200 (29%), Positives = 99/200 (49%), Gaps = 4/200 (2%) Frame = +3 Query: 6 EGFRSIVQTMGLGNLKPNIVVVRYPEIWRRENLTEIPSTFVSIINDCIIANKAVVIVKGL 185 EG ++Q+ GLG ++ N VV+ +P WR+ TF+ + A+ A+++ K + Sbjct: 772 EGLAHLIQSCGLGGMRHNSVVLGWPYGWRQSEDPRAWKTFIDTVRCTTAAHLALLVPKNI 831 Query: 186 DEWPNEFQRQY-GTIDLYWIVRDGGXXXXXXXXXXTKATFESCKIQVFCIAEEDTDAAEL 362 +P+ +R G ID++WIV DGG ++ C++++F +A+ D ++ ++ Sbjct: 832 AFYPSNHERYLEGHIDVWWIVHDGGMLMLLPFLLRQHKVWKKCRMRIFTVAQMDDNSIQM 891 Query: 363 KTDVKKFLYDLRMHAEVIVVTMKXXXXXXXXXXXXAQPDDSQEAY--TSAQRRISAYLSE 536 K D+ FLY LR+ AEV VV M D S Y T + S L + Sbjct: 892 KKDLAIFLYHLRLEAEVEVVEMH-------------NSDISAYTYERTLMMEQRSQMLRQ 938 Query: 537 MKET-TEREGRPQMVDGKQA 593 M+ T TER+ Q+V + + Sbjct: 939 MRLTKTERDREAQLVKDRHS 958
>S12A4_MOUSE (Q9JIS8) Solute carrier family 12 member 4 (Electroneutral| potassium-chloride cotransporter 1) (Erythroid K-Cl cotransporter 1) (mKCC1) Length = 1085 Score = 89.4 bits (220), Expect = 7e-18 Identities = 58/200 (29%), Positives = 99/200 (49%), Gaps = 4/200 (2%) Frame = +3 Query: 6 EGFRSIVQTMGLGNLKPNIVVVRYPEIWRRENLTEIPSTFVSIINDCIIANKAVVIVKGL 185 EG ++Q+ GLG ++ N VV+ +P WR+ TF+ + A+ A+++ K + Sbjct: 772 EGLAHLIQSCGLGGMRHNSVVLGWPYGWRQSEDPRAWKTFIDTVRCTTAAHLALLVPKNI 831 Query: 186 DEWPNEFQRQY-GTIDLYWIVRDGGXXXXXXXXXXTKATFESCKIQVFCIAEEDTDAAEL 362 +P+ +R G ID++WIV DGG ++ C++++F +A+ D ++ ++ Sbjct: 832 AFYPSNHERYLDGHIDVWWIVHDGGMLMLLPFLLRQHKVWKKCRMRIFTVAQMDDNSIQM 891 Query: 363 KTDVKKFLYDLRMHAEVIVVTMKXXXXXXXXXXXXAQPDDSQEAY--TSAQRRISAYLSE 536 K D+ FLY LR+ AEV VV M D S Y T + S L + Sbjct: 892 KKDLAIFLYHLRLEAEVEVVEMH-------------NSDISAYTYERTLMMEQRSQMLRQ 938 Query: 537 MKET-TEREGRPQMVDGKQA 593 M+ T TER+ Q+V + + Sbjct: 939 MRLTKTERDREAQLVKDRHS 958
>S12A6_MOUSE (Q924N4) Solute carrier family 12 member 6 (Electroneutral| potassium-chloride cotransporter 3) (K-Cl cotransporter 3) Length = 1150 Score = 89.0 bits (219), Expect = 1e-17 Identities = 56/203 (27%), Positives = 95/203 (46%), Gaps = 6/203 (2%) Frame = +3 Query: 6 EGFRSIVQTMGLGNLKPNIVVVRYPEIWRRENLTEIPSTFVSIINDCIIANKAVVIVKGL 185 EG ++Q+ GLG +K N VV+ +P WR+ TF+ + A+ A+++ K + Sbjct: 837 EGISHLIQSCGLGGMKHNTVVMGWPNGWRQSEDARAWKTFIGTVRVTTAAHLALLVAKNV 896 Query: 186 DEWPNEFQR-QYGTIDLYWIVRDGGXXXXXXXXXXTKATFESCKIQVFCIAEEDTDAAEL 362 +P+ ++ G ID+ WIV DGG + C I++F +A+ + ++ ++ Sbjct: 897 SFFPSNVEQFSEGNIDVRWIVHDGGMLMLLPFLLKQHKVWRKCSIRIFTVAQLEDNSIQM 956 Query: 363 KTDVKKFLYDLRMHAEVIVVTMKXXXXXXXXXXXXAQPDDSQEAYTSAQRRISAYLSEM- 539 K D+ FLY LR+ AEV VV M D AYT + + S+M Sbjct: 957 KKDLATFLYHLRIEAEVEVVEMH---------------DSDISAYTYERTLMMEQRSQML 1001 Query: 540 ----KETTEREGRPQMVDGKQAV 596 TER+ Q+V + ++ Sbjct: 1002 RHMRLSKTERDREAQLVKDRNSM 1024
>S12A5_MOUSE (Q91V14) Solute carrier family 12 member 5 (Electroneutral| potassium-chloride cotransporter 2) (K-Cl cotransporter 2) (Neuronal K-Cl cotransporter) (mKCC2) Length = 1115 Score = 89.0 bits (219), Expect = 1e-17 Identities = 44/142 (30%), Positives = 80/142 (56%), Gaps = 1/142 (0%) Frame = +3 Query: 6 EGFRSIVQTMGLGNLKPNIVVVRYPEIWRRENLTEIPSTFVSIINDCIIANKAVVIVKGL 185 +G ++Q+ GLG L+ N V+V +P WR++ + F+ ++ + + A+++ K + Sbjct: 752 DGVSHLIQSGGLGGLQHNTVLVGWPRNWRQKEDHQTWRNFIELVRETTAGHLALLVTKNV 811 Query: 186 DEWPNEFQR-QYGTIDLYWIVRDGGXXXXXXXXXXTKATFESCKIQVFCIAEEDTDAAEL 362 +P +R G+ID++WIV DGG + CK+++F +A+ D ++ ++ Sbjct: 812 SMFPGNPERFSEGSIDVWWIVHDGGMLMLLPFLLRHHKVWRKCKMRIFTVAQMDDNSIQM 871 Query: 363 KTDVKKFLYDLRMHAEVIVVTM 428 K D+ FLY LR+ AEV VV M Sbjct: 872 KKDLTTFLYHLRITAEVEVVEM 893
>S12A5_RAT (Q63633) Solute carrier family 12 member 5 (Electroneutral| potassium-chloride cotransporter 2) (K-Cl cotransporter 2) (Neuronal K-Cl cotransporter) (Furosemide-sensitive K-Cl cotransporter) (rKCC2) Length = 1116 Score = 89.0 bits (219), Expect = 1e-17 Identities = 44/142 (30%), Positives = 80/142 (56%), Gaps = 1/142 (0%) Frame = +3 Query: 6 EGFRSIVQTMGLGNLKPNIVVVRYPEIWRRENLTEIPSTFVSIINDCIIANKAVVIVKGL 185 +G ++Q+ GLG L+ N V+V +P WR++ + F+ ++ + + A+++ K + Sbjct: 752 DGVSHLIQSGGLGGLQHNTVLVGWPRNWRQKEDHQTWRNFIELVRETTAGHLALLVTKNV 811 Query: 186 DEWPNEFQR-QYGTIDLYWIVRDGGXXXXXXXXXXTKATFESCKIQVFCIAEEDTDAAEL 362 +P +R G+ID++WIV DGG + CK+++F +A+ D ++ ++ Sbjct: 812 SMFPGNPERFSEGSIDVWWIVHDGGMLMLLPFLLRHHKVWRKCKMRIFTVAQMDDNSIQM 871 Query: 363 KTDVKKFLYDLRMHAEVIVVTM 428 K D+ FLY LR+ AEV VV M Sbjct: 872 KKDLTTFLYHLRITAEVEVVEM 893
>S12A5_HUMAN (Q9H2X9) Solute carrier family 12 member 5 (Electroneutral| potassium-chloride cotransporter 2) (Erythroid K-Cl cotransporter 2) (Neuronal K-Cl cotransporter) (hKCC2) Length = 1116 Score = 89.0 bits (219), Expect = 1e-17 Identities = 44/142 (30%), Positives = 80/142 (56%), Gaps = 1/142 (0%) Frame = +3 Query: 6 EGFRSIVQTMGLGNLKPNIVVVRYPEIWRRENLTEIPSTFVSIINDCIIANKAVVIVKGL 185 +G ++Q+ GLG L+ N V+V +P WR++ + F+ ++ + + A+++ K + Sbjct: 752 DGVSHLIQSGGLGGLQHNTVLVGWPRNWRQKEDHQTWRNFIELVRETTAGHLALLVTKNV 811 Query: 186 DEWPNEFQR-QYGTIDLYWIVRDGGXXXXXXXXXXTKATFESCKIQVFCIAEEDTDAAEL 362 +P +R G+ID++WIV DGG + CK+++F +A+ D ++ ++ Sbjct: 812 SMFPGNPERFSEGSIDVWWIVHDGGMLMLLPFLLRHHKVWRKCKMRIFTVAQMDDNSIQM 871 Query: 363 KTDVKKFLYDLRMHAEVIVVTM 428 K D+ FLY LR+ AEV VV M Sbjct: 872 KKDLTTFLYHLRITAEVEVVEM 893
>YRD3_CAEEL (Q09573) Hypothetical protein K02A2.3| Length = 1020 Score = 84.7 bits (208), Expect = 2e-16 Identities = 48/187 (25%), Positives = 97/187 (51%), Gaps = 1/187 (0%) Frame = +3 Query: 21 IVQTMGLGNLKPNIVVVRYPEIWRRENLTEIPSTFVSIINDCIIANKAVVIVKGLDEWPN 200 + Q++G+G L+PN +++ +P +N E+ II+ N +++ KG+ ++P Sbjct: 714 LYQSIGIGGLRPNTILLNWPN---EKNPDELVLFAEEIIHGAANDN-CLIVTKGITDFPE 769 Query: 201 EFQRQYGTIDLYWIVRDGGXXXXXXXXXXTKATFESCKIQVFCIAEED-TDAAELKTDVK 377 +R G ID++WIV+DGG ++ C +++F ++E+D T + ++K ++ Sbjct: 770 YSERLTGFIDIWWIVQDGGILMLIAYLLRQHKVWKGCTLRIFAVSEQDSTKSEDMKAGLQ 829 Query: 378 KFLYDLRMHAEVIVVTMKXXXXXXXXXXXXAQPDDSQEAYTSAQRRISAYLSEMKETTER 557 K++Y LR+ AE+ +V + A+ + Q+ +R S YL++ E Sbjct: 830 KYIYMLRIDAELFIVDLLDMEVSDEVVEKAAEVERKQKEREEMRRSKSGYLND--GFMED 887 Query: 558 EGRPQMV 578 G+P+ V Sbjct: 888 NGKPRQV 894
>S12A3_RAT (P55018) Solute carrier family 12 member 3 (Thiazide-sensitive| sodium-chloride cotransporter) (Na-Cl symporter) Length = 1002 Score = 52.0 bits (123), Expect = 1e-06 Identities = 36/129 (27%), Positives = 59/129 (45%), Gaps = 23/129 (17%) Frame = +3 Query: 9 GFRSIVQTMGLGNLKPNIVVVRYPEIWRRENLTEIPSTFVSIINDCIIANKAVVIVK--- 179 G + ++Q GLG +KPNI+VV + + W+ + + ++ I++D N V I++ Sbjct: 718 GVQILMQASGLGRMKPNILVVGFKKNWQSAHPATLED-YIGILHDAFDFNYGVCIMRMRE 776 Query: 180 GL------------------DEWPNEFQRQYG--TIDLYWIVRDGGXXXXXXXXXXTKAT 299 GL ++ FQ + G TID+YW+ DGG K Sbjct: 777 GLNVSEALQTHTAPEALVQEEQTSTIFQSEQGKKTIDIYWLFDDGGLTLLIPYLLHRKKR 836 Query: 300 FESCKIQVF 326 + CKI+VF Sbjct: 837 WGKCKIRVF 845
>S12A1_RABIT (P55015) Solute carrier family 12 member 1 (Bumetanide-sensitive| sodium-(potassium)-chloride cotransporter 2) (Kidney-specific Na-K-Cl symporter) Length = 1099 Score = 51.2 bits (121), Expect = 2e-06 Identities = 26/58 (44%), Positives = 37/58 (63%) Frame = +3 Query: 6 EGFRSIVQTMGLGNLKPNIVVVRYPEIWRRENLTEIPSTFVSIINDCIIANKAVVIVK 179 +G RS++Q GLG +KPN +V+ Y + WR+ LTEI +V II+D VVIV+ Sbjct: 758 DGVRSLLQASGLGRMKPNTLVIGYKKKWRKAPLTEI-ENYVGIIHDAFDFEIGVVIVR 814 Score = 30.4 bits (67), Expect = 4.0 Identities = 10/36 (27%), Positives = 20/36 (55%) Frame = +3 Query: 219 GTIDLYWIVRDGGXXXXXXXXXXTKATFESCKIQVF 326 GTID++W+ DGG + ++ CK++++ Sbjct: 909 GTIDVWWLFDDGGLTLLIPYILTLRKKWKDCKLRIY 944
>S12A1_HUMAN (Q13621) Solute carrier family 12 member 1 (Bumetanide-sensitive| sodium-(potassium)-chloride cotransporter 2) (Kidney-specific Na-K-Cl symporter) Length = 1099 Score = 51.2 bits (121), Expect = 2e-06 Identities = 26/58 (44%), Positives = 37/58 (63%) Frame = +3 Query: 6 EGFRSIVQTMGLGNLKPNIVVVRYPEIWRRENLTEIPSTFVSIINDCIIANKAVVIVK 179 +G RS++Q GLG +KPN +V+ Y + WR+ LTEI +V II+D VVIV+ Sbjct: 758 DGVRSLLQASGLGRMKPNTLVIGYKKNWRKAPLTEI-ENYVGIIHDAFDFEIGVVIVR 814 Score = 31.2 bits (69), Expect = 2.4 Identities = 10/40 (25%), Positives = 23/40 (57%) Frame = +3 Query: 207 QRQYGTIDLYWIVRDGGXXXXXXXXXXTKATFESCKIQVF 326 +++ GTID++W+ DGG + ++ CK++++ Sbjct: 905 KQEKGTIDVWWLFDDGGLTLLIPYILTLRKKWKDCKLRIY 944
>S12A3_MOUSE (P59158) Solute carrier family 12 member 3 (Thiazide-sensitive| sodium-chloride cotransporter) (Na-Cl symporter) Length = 1002 Score = 50.8 bits (120), Expect = 3e-06 Identities = 34/129 (26%), Positives = 58/129 (44%), Gaps = 23/129 (17%) Frame = +3 Query: 9 GFRSIVQTMGLGNLKPNIVVVRYPEIWRRENLTEIPSTFVSIINDCIIANKAVVIVK--- 179 G + ++Q GLG +KPNI+VV + W+ + + ++ +++D N V +++ Sbjct: 718 GVQILMQASGLGRMKPNILVVGFKRNWQSAHPATVED-YIGVLHDAFDFNYGVCVMRMRE 776 Query: 180 GL------------------DEWPNEFQRQYG--TIDLYWIVRDGGXXXXXXXXXXTKAT 299 GL ++ FQ + G TID+YW+ DGG K Sbjct: 777 GLNVSEALQTHTTPEALIQEEQASTIFQSEQGKKTIDIYWLFDDGGLTLLIPYLLHRKKR 836 Query: 300 FESCKIQVF 326 + CKI+VF Sbjct: 837 WGKCKIRVF 845
>S12A1_RAT (P55016) Solute carrier family 12 member 1 (Bumetanide-sensitive| sodium-(potassium)-chloride cotransporter 2) (Kidney-specific Na-K-Cl symporter) Length = 1095 Score = 48.9 bits (115), Expect = 1e-05 Identities = 24/58 (41%), Positives = 37/58 (63%) Frame = +3 Query: 6 EGFRSIVQTMGLGNLKPNIVVVRYPEIWRRENLTEIPSTFVSIINDCIIANKAVVIVK 179 +G RS++Q GLG +KPN +V+ Y + WR+ L+E+ +V II+D VVIV+ Sbjct: 754 DGVRSLLQASGLGRMKPNTLVIGYKKNWRKAPLSEL-ENYVGIIHDAFDFEIGVVIVR 810 Score = 31.6 bits (70), Expect = 1.8 Identities = 26/130 (20%), Positives = 52/130 (40%), Gaps = 14/130 (10%) Frame = +3 Query: 219 GTIDLYWIVRDGGXXXXXXXXXXTKATFESCKIQVFC------IAEEDTDAAELKTDVKK 380 GTID++W+ DGG + ++ CK++++ I EE A L + + Sbjct: 905 GTIDVWWLFDDGGLTLLIPYILTLRKKWKDCKLRIYVGGKINRIEEEKISMASLLSKFRI 964 Query: 381 FLYDLRMHAEVIVVTMKXXXXXXXXXXXXAQPDDSQEAYTSAQRR--------ISAYLSE 536 D+ + ++ + K + +S + T+A++ A L Sbjct: 965 KFADIHIIGDINIKPNKESWKVFEEMIEPYRLHESHKDLTTAEKLKRESPWKITDAELEA 1024 Query: 537 MKETTEREGR 566 +KE + R+ R Sbjct: 1025 VKEKSYRQVR 1034
>S12A1_MOUSE (P55014) Solute carrier family 12 member 1 (Bumetanide-sensitive| sodium-(potassium)-chloride cotransporter 2) (BSC1) (Kidney-specific Na-K-Cl symporter) Length = 1095 Score = 48.9 bits (115), Expect = 1e-05 Identities = 24/58 (41%), Positives = 37/58 (63%) Frame = +3 Query: 6 EGFRSIVQTMGLGNLKPNIVVVRYPEIWRRENLTEIPSTFVSIINDCIIANKAVVIVK 179 +G RS++Q GLG +KPN +V+ Y + WR+ L+E+ +V II+D VVIV+ Sbjct: 754 DGVRSLLQASGLGRMKPNTLVIGYKKNWRKAPLSEL-ENYVGIIHDAFDFEIGVVIVR 810 Score = 31.6 bits (70), Expect = 1.8 Identities = 26/130 (20%), Positives = 52/130 (40%), Gaps = 14/130 (10%) Frame = +3 Query: 219 GTIDLYWIVRDGGXXXXXXXXXXTKATFESCKIQVFC------IAEEDTDAAELKTDVKK 380 GTID++W+ DGG + ++ CK++++ I EE A L + + Sbjct: 905 GTIDVWWLFDDGGLTLLIPYILTLRKKWKDCKLRIYVGGKITRIEEEKISMASLLSKFRI 964 Query: 381 FLYDLRMHAEVIVVTMKXXXXXXXXXXXXAQPDDSQEAYTSAQRR--------ISAYLSE 536 D+ + ++ + K + +S + T+A++ A L Sbjct: 965 KFADIHIIGDINIKPNKESWKVFEEMIEPYRLHESHKDLTTAEKLKRESPWKITDAELEA 1024 Query: 537 MKETTEREGR 566 +KE + R+ R Sbjct: 1025 VKEKSYRQVR 1034
>S12A3_HUMAN (P55017) Solute carrier family 12 member 3 (Thiazide-sensitive| sodium-chloride cotransporter) (Na-Cl symporter) Length = 1021 Score = 45.8 bits (107), Expect = 9e-05 Identities = 35/146 (23%), Positives = 59/146 (40%), Gaps = 40/146 (27%) Frame = +3 Query: 9 GFRSIVQTMGLGNLKPNIVVVRYPEIWRRENLTEIPSTFVSIINDCIIANKAVVIVK--- 179 G + ++Q GLG +KPNI+VV + + W+ + + ++ I++D N V +++ Sbjct: 720 GVQILMQAAGLGRMKPNILVVGFKKNWQSAHPATV-EDYIGILHDAFEFNYGVCVMRMRE 778 Query: 180 GL-----------------------------------DEWPNEFQRQYG--TIDLYWIVR 248 GL ++ FQ + G TID+YW+ Sbjct: 779 GLNVSKMMQAHINPVFDPAEDGKEASARVDPKALVKEEQATTIFQSEQGKKTIDIYWLFD 838 Query: 249 DGGXXXXXXXXXXTKATFESCKIQVF 326 DGG K + CKI+VF Sbjct: 839 DGGLTLLIPYLLGRKRRWSKCKIRVF 864
>S12A2_MOUSE (P55012) Solute carrier family 12 member 2 (Bumetanide-sensitive| sodium-(potassium)-chloride cotransporter 1) (Basolateral Na-K-Cl symporter) Length = 1205 Score = 40.4 bits (93), Expect = 0.004 Identities = 25/73 (34%), Positives = 36/73 (49%), Gaps = 5/73 (6%) Frame = +3 Query: 189 EWPNEFQRQYG--TIDLYWIVRDGGXXXXXXXXXXTKATFESCKIQVFC---IAEEDTDA 353 E +FQ++ G TID++W+ DGG TK ++ CKI+VF I D D Sbjct: 1003 EASTQFQKKQGKNTIDVWWLFDDGGLTLLIPYLLTTKKKWKDCKIRVFIGGKINRIDHDR 1062 Query: 354 AELKTDVKKFLYD 392 + T + KF D Sbjct: 1063 RAMATLLSKFRID 1075 Score = 37.0 bits (84), Expect = 0.043 Identities = 17/64 (26%), Positives = 38/64 (59%), Gaps = 3/64 (4%) Frame = +3 Query: 6 EGFRSIVQTMGLGNLKPNIVVVRYPEIWRRENLTEIPSTFVSIINDCIIANKAVVIVK-- 179 EG + ++Q GLG +KPN +V+ + + W + ++ ++ ++++ +D VV+++ Sbjct: 858 EGAQYLMQAAGLGRMKPNTLVLGFKKDWLQADMRDV-DMYINLFHDAFDIQFGVVVIRLK 916 Query: 180 -GLD 188 GLD Sbjct: 917 EGLD 920
>S12A2_HUMAN (P55011) Solute carrier family 12 member 2 (Bumetanide-sensitive| sodium-(potassium)-chloride cotransporter 1) (Basolateral Na-K-Cl symporter) Length = 1212 Score = 40.4 bits (93), Expect = 0.004 Identities = 25/73 (34%), Positives = 36/73 (49%), Gaps = 5/73 (6%) Frame = +3 Query: 189 EWPNEFQRQYG--TIDLYWIVRDGGXXXXXXXXXXTKATFESCKIQVFC---IAEEDTDA 353 E +FQ++ G TID++W+ DGG TK ++ CKI+VF I D D Sbjct: 1010 EASTQFQKKQGKNTIDVWWLFDDGGLTLLIPYLLTTKKKWKDCKIRVFIGGKINRIDHDR 1069 Query: 354 AELKTDVKKFLYD 392 + T + KF D Sbjct: 1070 RAMATLLSKFRID 1082 Score = 37.4 bits (85), Expect = 0.033 Identities = 17/64 (26%), Positives = 38/64 (59%), Gaps = 3/64 (4%) Frame = +3 Query: 6 EGFRSIVQTMGLGNLKPNIVVVRYPEIWRRENLTEIPSTFVSIINDCIIANKAVVIVK-- 179 EG + ++Q GLG +KPN +V+ + + W + ++ ++ ++++ +D VV+++ Sbjct: 865 EGAQYLMQAAGLGRMKPNTLVLGFKKDWLQADMRDV-DMYINLFHDAFDIQYGVVVIRLK 923 Query: 180 -GLD 188 GLD Sbjct: 924 EGLD 927
>S12A2_SQUAC (P55013) Solute carrier family 12 member 2 (Bumetanide-sensitive| sodium-(potassium)-chloride cotransporter 1) (NA-K-CL symporter) (NKCC) Length = 1191 Score = 40.4 bits (93), Expect = 0.004 Identities = 24/70 (34%), Positives = 36/70 (51%), Gaps = 5/70 (7%) Frame = +3 Query: 198 NEFQRQYG--TIDLYWIVRDGGXXXXXXXXXXTKATFESCKIQVFC---IAEEDTDAAEL 362 ++FQ++ G TID++W+ DGG TK ++ CKI+VF I D D + Sbjct: 992 SQFQKKQGKGTIDVWWLFDDGGLTLLIPYLLTTKKKWKDCKIRVFIGGKINRIDHDRRTM 1051 Query: 363 KTDVKKFLYD 392 T + KF D Sbjct: 1052 ATLLSKFRID 1061 Score = 37.0 bits (84), Expect = 0.043 Identities = 15/58 (25%), Positives = 35/58 (60%) Frame = +3 Query: 6 EGFRSIVQTMGLGNLKPNIVVVRYPEIWRRENLTEIPSTFVSIINDCIIANKAVVIVK 179 EG + ++Q +GLG ++PN +V + + WR+ + ++ +++ I+D VV+++ Sbjct: 838 EGTQFLLQAVGLGRMRPNTLVFGFKKDWRQALMKDV-ENYINAIHDAFDYQYGVVVIR 894
>S12A3_PSEAM (P55019) Solute carrier family 12 member 3 (Thiazide-sensitive| sodium-chloride cotransporter) (Na-Cl symporter) Length = 1023 Score = 40.0 bits (92), Expect = 0.005 Identities = 37/178 (20%), Positives = 68/178 (38%), Gaps = 53/178 (29%) Frame = +3 Query: 9 GFRSIVQTMGLGNLKPNIVVVRYPEIWRRENLTEIPSTFVSIINDCIIANKAVVIVK--- 179 G ++Q GLG +KPN++++ + + W ++ + ++ I++D + V +++ Sbjct: 712 GVNMLLQGAGLGRIKPNVLLMGFKKDWGCDS-PQAAHHYIGILHDAFDLHYGVCVLRVKE 770 Query: 180 --------------GLDEWPNE-----------------------------FQRQYG--T 224 G D P FQ++ G T Sbjct: 771 GLDASHPPQCHVNPGFDGGPESINTVCAPACVQTSVTSSVSMDPDPQPSSVFQKKQGKKT 830 Query: 225 IDLYWIVRDGGXXXXXXXXXXTKATFESCKIQVFCIAEEDTDAAELKTD-----VKKF 383 ID+YW+ DGG + + CK++VF DTD E + + +KKF Sbjct: 831 IDIYWLSDDGGLTLLLPYLLTRRKRWAGCKVRVF--VGGDTDKKEEQKEEVLALIKKF 886
>NKCL_MANSE (Q25479) Bumetanide-sensitive sodium-(potassium)-chloride| cotransporter (Na-K-CL symporter) Length = 1060 Score = 34.7 bits (78), Expect = 0.21 Identities = 11/43 (25%), Positives = 26/43 (60%) Frame = +3 Query: 207 QRQYGTIDLYWIVRDGGXXXXXXXXXXTKATFESCKIQVFCIA 335 +++ GT+D++W+ DGG ++ + +CK+++F +A Sbjct: 877 KQESGTLDVWWLYDDGGLTILLPYIISQRSAWANCKLRIFALA 919 Score = 32.7 bits (73), Expect = 0.81 Identities = 20/63 (31%), Positives = 34/63 (53%), Gaps = 3/63 (4%) Frame = +3 Query: 9 GFRSIVQTMGLGNLKPNIVVVRYPEIWRRENLTEIPSTFVSIINDCIIANKAVVIVK--- 179 G R++VQ G+G L PN++++ Y W ++ S F ++++ AV IV+ Sbjct: 704 GARALVQGSGVGRLAPNVLLMGYKSDWTTCPANDLVSYF-NVLHTAFENRLAVAIVRVSG 762 Query: 180 GLD 188 GLD Sbjct: 763 GLD 765
>NLGN3_RAT (Q62889) Neuroligin-3 precursor (Gliotactin homolog)| Length = 848 Score = 30.0 bits (66), Expect = 5.3 Identities = 13/29 (44%), Positives = 18/29 (62%) Frame = -1 Query: 93 GAKFQGTAPQQYLASSSLGPSSEQCCGSP 7 GA GTAP++ LA+ LGP+ +C P Sbjct: 751 GAPELGTAPEEELAALQLGPTHHECEAGP 779
>NLGN3_MOUSE (Q8BYM5) Neuroligin-3 precursor (Gliotactin homolog)| Length = 825 Score = 30.0 bits (66), Expect = 5.3 Identities = 13/29 (44%), Positives = 18/29 (62%) Frame = -1 Query: 93 GAKFQGTAPQQYLASSSLGPSSEQCCGSP 7 GA GTAP++ LA+ LGP+ +C P Sbjct: 728 GAPELGTAPEEELAALQLGPTHHECEAGP 756 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 84,758,513 Number of Sequences: 219361 Number of extensions: 1626722 Number of successful extensions: 3771 Number of sequences better than 10.0: 26 Number of HSP's better than 10.0 without gapping: 3653 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 3757 length of database: 80,573,946 effective HSP length: 107 effective length of database: 57,102,319 effective search space used: 5196311029 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
