ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | basd12k23 |
|---|---|
| Clone Library Name | barley_pub |
>BRI1_ARATH (O22476) BRASSINOSTEROID INSENSITIVE 1 precursor (EC 2.7.11.1)| (AtBRI1) (Brassinosteroid LRR receptor kinase) Length = 1196 Score = 97.1 bits (240), Expect = 4e-20 Identities = 46/101 (45%), Positives = 69/101 (68%) Frame = +3 Query: 348 ELSFDELKEKTDDFGSKALVGEGSYGRVYYAVLENGTHVAVKKLDTSADPEPDNEFIAQV 527 +L+F +L + T+ F + +L+G G +G VY A+L++G+ VA+KKL + D EF+A++ Sbjct: 870 KLTFADLLQATNGFHNDSLIGSGGFGDVYKAILKDGSAVAIKKL-IHVSGQGDREFMAEM 928 Query: 528 SVISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDILH 650 I ++KH + V LLGYC GD+RLL YEF GSL D+LH Sbjct: 929 ETIGKIKHRNLVPLLGYCKVGDERLLVYEFMKYGSLEDVLH 969
>BRL2_ARATH (Q9ZPS9) Serine/threonine-protein kinase BRI1-like 2 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 2) (Protein VASCULAR HIGHWAY 1) Length = 1143 Score = 95.5 bits (236), Expect = 1e-19 Identities = 44/105 (41%), Positives = 70/105 (66%) Frame = +3 Query: 339 QVPELSFDELKEKTDDFGSKALVGEGSYGRVYYAVLENGTHVAVKKLDTSADPEPDNEFI 518 Q+ +L F +L E T+ F + +++G G +G V+ A L++G+ VA+KKL + D EF+ Sbjct: 822 QLRKLKFSQLIEATNGFSAASMIGHGGFGEVFKATLKDGSSVAIKKL-IRLSCQGDREFM 880 Query: 519 AQVSVISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDILHG 653 A++ + ++KH + V LLGYC G++RLL YEF GSL ++LHG Sbjct: 881 AEMETLGKIKHRNLVPLLGYCKIGEERLLVYEFMQYGSLEEVLHG 925
>BRI1_LYCPE (Q8L899) Systemin receptor SR160 precursor (EC 2.7.11.1)| (Brassinosteroid LRR receptor kinase) Length = 1207 Score = 92.8 bits (229), Expect = 8e-19 Identities = 46/101 (45%), Positives = 67/101 (66%) Frame = +3 Query: 348 ELSFDELKEKTDDFGSKALVGEGSYGRVYYAVLENGTHVAVKKLDTSADPEPDNEFIAQV 527 +L+F +L E T+ F + +LVG G +G VY A L++G+ VA+KKL + D EF A++ Sbjct: 875 KLTFADLLEATNGFHNDSLVGSGGFGDVYKAQLKDGSVVAIKKL-IHVSGQGDREFTAEM 933 Query: 528 SVISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDILH 650 I ++KH + V LLGYC G++RLL YE+ GSL D+LH Sbjct: 934 ETIGKIKHRNLVPLLGYCKVGEERLLVYEYMKYGSLEDVLH 974
>BRI1_LYCES (Q8GUQ5) Brassinosteroid LRR receptor kinase precursor (EC 2.7.11.1)| (tBRI1) (Altered brassinolide sensitivity 1) (Systemin receptor SR160) Length = 1207 Score = 92.8 bits (229), Expect = 8e-19 Identities = 46/101 (45%), Positives = 67/101 (66%) Frame = +3 Query: 348 ELSFDELKEKTDDFGSKALVGEGSYGRVYYAVLENGTHVAVKKLDTSADPEPDNEFIAQV 527 +L+F +L E T+ F + +LVG G +G VY A L++G+ VA+KKL + D EF A++ Sbjct: 875 KLTFADLLEATNGFHNDSLVGSGGFGDVYKAQLKDGSVVAIKKL-IHVSGQGDREFTAEM 933 Query: 528 SVISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDILH 650 I ++KH + V LLGYC G++RLL YE+ GSL D+LH Sbjct: 934 ETIGKIKHRNLVPLLGYCKVGEERLLVYEYMKYGSLEDVLH 974
>BRL1_ARATH (Q9ZWC8) Serine/threonine-protein kinase BRI1-like 1 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 1) Length = 1166 Score = 90.1 bits (222), Expect = 5e-18 Identities = 44/101 (43%), Positives = 65/101 (64%) Frame = +3 Query: 348 ELSFDELKEKTDDFGSKALVGEGSYGRVYYAVLENGTHVAVKKLDTSADPEPDNEFIAQV 527 +L+F L E T+ F ++ +VG G +G VY A L +G+ VA+KKL + D EF+A++ Sbjct: 846 KLTFAHLLEATNGFSAETMVGSGGFGEVYKAQLRDGSVVAIKKL-IRITGQGDREFMAEM 904 Query: 528 SVISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDILH 650 I ++KH + V LLGYC G++RLL YE+ GSL +LH Sbjct: 905 ETIGKIKHRNLVPLLGYCKVGEERLLVYEYMKWGSLETVLH 945
>CRI4_MAIZE (O24585) Putative receptor protein kinase CRINKLY4 precursor (EC| 2.7.11.1) Length = 901 Score = 89.7 bits (221), Expect = 7e-18 Identities = 44/103 (42%), Positives = 68/103 (66%), Gaps = 1/103 (0%) Frame = +3 Query: 348 ELSFDELKEKTDDFGSKALVGEGSYGRVYYAVLENGTHVAVKKLDTSADPEPDN-EFIAQ 524 E S++EL++ T F + VG+GS+ V+ +L +GT VAVK+ ++D + + EF + Sbjct: 492 EFSYEELEQATGGFSEDSQVGKGSFSCVFKGILRDGTVVAVKRAIKASDVKKSSKEFHNE 551 Query: 525 VSVISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDILHG 653 + ++SRL H H ++LLGYC +G +RLL YEF GSL+ LHG Sbjct: 552 LDLLSRLNHAHLLNLLGYCEDGSERLLVYEFMAHGSLYQHLHG 594
>BRL3_ARATH (Q9LJF3) Serine/threonine-protein kinase BRI1-like 3 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 3) Length = 1164 Score = 88.6 bits (218), Expect = 1e-17 Identities = 43/101 (42%), Positives = 65/101 (64%) Frame = +3 Query: 348 ELSFDELKEKTDDFGSKALVGEGSYGRVYYAVLENGTHVAVKKLDTSADPEPDNEFIAQV 527 +L+F L E T+ F + +++G G +G VY A L +G+ VA+KKL + D EF+A++ Sbjct: 845 KLTFAHLLEATNGFSADSMIGSGGFGDVYKAKLADGSVVAIKKL-IQVTGQGDREFMAEM 903 Query: 528 SVISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDILH 650 I ++KH + V LLGYC G++RLL YE+ GSL +LH Sbjct: 904 ETIGKIKHRNLVPLLGYCKIGEERLLVYEYMKYGSLETVLH 944
>PBS1_ARATH (Q9FE20) Serine/threonine-protein kinase PBS1 (EC 2.7.11.1)| (AvrPphB susceptible protein 1) Length = 456 Score = 85.1 bits (209), Expect = 2e-16 Identities = 46/100 (46%), Positives = 65/100 (65%), Gaps = 1/100 (1%) Frame = +3 Query: 354 SFDELKEKTDDFGSKALVGEGSYGRVYYAVLEN-GTHVAVKKLDTSADPEPDNEFIAQVS 530 +F EL T +F +GEG +GRVY L++ G VAVK+LD + + + EF+ +V Sbjct: 75 AFRELAAATMNFHPDTFLGEGGFGRVYKGRLDSTGQVVAVKQLDRNG-LQGNREFLVEVL 133 Query: 531 VISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDILH 650 ++S L H + V+L+GYC +GDQRLL YEF +GSL D LH Sbjct: 134 MLSLLHHPNLVNLIGYCADGDQRLLVYEFMPLGSLEDHLH 173
>RLCK7_ARATH (Q9LQQ8) Probable serine/threonine-protein kinase RLCKVII (EC| 2.7.11.1) Length = 423 Score = 80.1 bits (196), Expect = 5e-15 Identities = 42/100 (42%), Positives = 60/100 (60%), Gaps = 1/100 (1%) Frame = +3 Query: 354 SFDELKEKTDDFGSKALVGEGSYGRVYYAVLENGTHV-AVKKLDTSADPEPDNEFIAQVS 530 +F EL E T +F S +GEG +G+V+ +E V A+K+LD + + EF+ +V Sbjct: 92 TFQELAEATGNFRSDCFLGEGGFGKVFKGTIEKLDQVVAIKQLDRNG-VQGIREFVVEVL 150 Query: 531 VISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDILH 650 +S H + V L+G+C EGDQRLL YE+ GSL D LH Sbjct: 151 TLSLADHPNLVKLIGFCAEGDQRLLVYEYMPQGSLEDHLH 190
>NORK_MEDTR (Q8L4H4) Nodulation receptor kinase precursor (EC 2.7.11.1) (Does| not make infections protein 2) (Symbiosis receptor-like kinase) (MtSYMRK) Length = 925 Score = 79.7 bits (195), Expect = 7e-15 Identities = 41/107 (38%), Positives = 68/107 (63%) Frame = +3 Query: 333 SIQVPELSFDELKEKTDDFGSKALVGEGSYGRVYYAVLENGTHVAVKKLDTSADPEPDNE 512 S+ V + + +++ T+ + K L+GEG +G VY L++G VAVK + +S + E Sbjct: 580 SVSVKPFTLEYIEQATEQY--KTLIGEGGFGSVYRGTLDDGQEVAVK-VRSSTSTQGTRE 636 Query: 513 FIAQVSVISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDILHG 653 F +++++S ++HE+ V LLGYC E DQ++L Y F + GSL D L+G Sbjct: 637 FDNELNLLSAIQHENLVPLLGYCNEYDQQILVYPFMSNGSLLDRLYG 683
>TMK1_ARATH (P43298) Putative receptor protein kinase TMK1 precursor (EC| 2.7.11.1) Length = 942 Score = 79.0 bits (193), Expect = 1e-14 Identities = 41/120 (34%), Positives = 73/120 (60%), Gaps = 6/120 (5%) Frame = +3 Query: 294 GFTQIGDQGKAPPSIQVPE-----LSFDELKEKTDDFGSKALVGEGSYGRVYYAVLENGT 458 G +++GD +IQ+ E +S L+ T++F S ++G G +G VY L +GT Sbjct: 558 GTSEVGD------NIQMVEAGNMLISIQVLRSVTNNFSSDNILGSGGFGVVYKGELHDGT 611 Query: 459 HVAVKKLDTSADPEPD-NEFIAQVSVISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSL 635 +AVK+++ EF ++++V+++++H H V LLGYCL+G+++LL YE+ G+L Sbjct: 612 KIAVKRMENGVIAGKGFAEFKSEIAVLTKVRHRHLVTLLGYCLDGNEKLLVYEYMPQGTL 671
>EXS_ARATH (Q9LYN8) Leucine-rich repeat receptor protein kinase EXS precursor| (EC 2.7.11.1) (Extra sporogenous cells protein) (EXCESS MICROSPOROCYTES1 protein) Length = 1192 Score = 78.6 bits (192), Expect = 2e-14 Identities = 47/152 (30%), Positives = 76/152 (50%), Gaps = 7/152 (4%) Frame = +3 Query: 201 MRRWFCCAHVDTPYEENGDEFPHSPERANGNGFTQIGDQGKAPPSIQVP-------ELSF 359 +RRW V + E + N + G + + P SI + ++ Sbjct: 848 LRRWAMTKRVKQRDDPERMEESRLKGFVDQNLYFLSGSRSREPLSINIAMFEQPLLKVRL 907 Query: 360 DELKEKTDDFGSKALVGEGSYGRVYYAVLENGTHVAVKKLDTSADPEPDNEFIAQVSVIS 539 ++ E TD F K ++G+G +G VY A L VAVKKL + A + + EF+A++ + Sbjct: 908 GDIVEATDHFSKKNIIGDGGFGTVYKACLPGEKTVAVKKL-SEAKTQGNREFMAEMETLG 966 Query: 540 RLKHEHFVDLLGYCLEGDQRLLAYEFATMGSL 635 ++KH + V LLGYC +++LL YE+ GSL Sbjct: 967 KVKHPNLVSLLGYCSFSEEKLLVYEYMVNGSL 998
>PSKR_DAUCA (Q8LPB4) Phytosulfokine receptor precursor (EC 2.7.11.1)| (Phytosulfokine LRR receptor kinase) Length = 1021 Score = 77.0 bits (188), Expect = 4e-14 Identities = 41/101 (40%), Positives = 58/101 (57%) Frame = +3 Query: 348 ELSFDELKEKTDDFGSKALVGEGSYGRVYYAVLENGTHVAVKKLDTSADPEPDNEFIAQV 527 ELS D++ + T F ++G G +G VY A L +GT VA+K+L + D EF A+V Sbjct: 730 ELSLDDILKSTSSFNQANIIGCGGFGLVYKATLPDGTKVAIKRLSGDTG-QMDREFQAEV 788 Query: 528 SVISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDILH 650 +SR +H + V LLGYC + +LL Y + GSL LH Sbjct: 789 ETLSRAQHPNLVHLLGYCNYKNDKLLIYSYMDNGSLDYWLH 829
>NORK_PEA (Q8LKZ1) Nodulation receptor kinase precursor (EC 2.7.11.1)| Length = 924 Score = 76.3 bits (186), Expect = 8e-14 Identities = 40/107 (37%), Positives = 67/107 (62%) Frame = +3 Query: 333 SIQVPELSFDELKEKTDDFGSKALVGEGSYGRVYYAVLENGTHVAVKKLDTSADPEPDNE 512 S+ V + + ++ T+ + K L+GEG +G VY L++G VAVK + ++ + E Sbjct: 579 SVSVKPFTLEYIELATEKY--KTLIGEGGFGSVYRGTLDDGQEVAVK-VRSATSTQGTRE 635 Query: 513 FIAQVSVISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDILHG 653 F +++++S ++HE+ V LLGYC E DQ++L Y F + GSL D L+G Sbjct: 636 FDNELNLLSAIQHENLVPLLGYCNEYDQQILVYPFMSNGSLLDRLYG 682
>PSKR_ARATH (Q9ZVR7) Putative phytosulfokine receptor precursor (EC 2.7.11.1)| (Phytosulfokine LRR receptor kinase) Length = 1008 Score = 74.7 bits (182), Expect = 2e-13 Identities = 50/153 (32%), Positives = 74/153 (48%) Frame = +3 Query: 192 LVIMRRWFCCAHVDTPYEENGDEFPHSPERANGNGFTQIGDQGKAPPSIQVPELSFDELK 371 L+++R VD EE+ E N +IG + ELS+D+L Sbjct: 677 LIVLRARRRSGEVDPEIEES--------ESMNRKELGEIGSKLVVLFQSNDKELSYDDLL 728 Query: 372 EKTDDFGSKALVGEGSYGRVYYAVLENGTHVAVKKLDTSADPEPDNEFIAQVSVISRLKH 551 + T+ F ++G G +G VY A L +G VA+KKL + + EF A+V +SR +H Sbjct: 729 DSTNSFDQANIIGCGGFGMVYKATLPDGKKVAIKKLSGDCG-QIEREFEAEVETLSRAQH 787 Query: 552 EHFVDLLGYCLEGDQRLLAYEFATMGSLHDILH 650 + V L G+C + RLL Y + GSL LH Sbjct: 788 PNLVLLRGFCFYKNDRLLIYSYMENGSLDYWLH 820
>SRK6_BRAOE (Q09092) Putative serine/threonine-protein kinase receptor| precursor (EC 2.7.11.1) (S-receptor kinase) (SRK) Length = 849 Score = 72.8 bits (177), Expect = 8e-13 Identities = 37/106 (34%), Positives = 67/106 (63%) Frame = +3 Query: 336 IQVPELSFDELKEKTDDFGSKALVGEGSYGRVYYAVLENGTHVAVKKLDTSADPEPDNEF 515 +++P + + + + T++F S +G+G +G VY L +G +AVK+L ++ D EF Sbjct: 511 LELPLIEMETVVKATENFSSCNKLGQGGFGIVYKGRLLDGKEIAVKRLSKTSVQGTD-EF 569 Query: 516 IAQVSVISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDILHG 653 + +V++I+RL+H + V +LG C+EGD+++L YE+ SL L G Sbjct: 570 MNEVTLIARLQHINLVQVLGCCIEGDEKMLIYEYLENLSLDSYLFG 615
>APK1A_ARATH (Q06548) Protein kinase APK1A, chloroplast precursor (EC 2.7.11.1)| Length = 410 Score = 72.0 bits (175), Expect = 1e-12 Identities = 42/121 (34%), Positives = 65/121 (53%), Gaps = 10/121 (8%) Frame = +3 Query: 315 QGKAPPSIQVPELSFDELKEKTDDFGSKALVGEGSYGRVYYAVLEN----------GTHV 464 +G+ S + SF ELK T +F +++GEG +G V+ ++ G + Sbjct: 44 EGEILQSPNLKSFSFAELKSATRNFRPDSVLGEGGFGCVFKGWIDEKSLTASRPGTGLVI 103 Query: 465 AVKKLDTSADPEPDNEFIAQVSVISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDI 644 AVKKL+ + E++A+V+ + + H H V L+GYCLE + RLL YEF GSL + Sbjct: 104 AVKKLNQDGW-QGHQEWLAEVNYLGQFSHRHLVKLIGYCLEDEHRLLVYEFMPRGSLENH 162 Query: 645 L 647 L Sbjct: 163 L 163
>IRAK1_MOUSE (Q62406) Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1)| (IRAK-1) (IRAK) (Pelle-like protein kinase) (mPLK) Length = 710 Score = 72.0 bits (175), Expect = 1e-12 Identities = 41/101 (40%), Positives = 55/101 (54%), Gaps = 3/101 (2%) Frame = +3 Query: 357 FDELKEKTDDFGSKALVGEGSYGRVYYAVLENGTHVAVKKLDTSADPE---PDNEFIAQV 527 F E+ + T +F + +GEG +G VY AV+ N T+ AVK+L AD E F+ +V Sbjct: 202 FCEISQGTCNFSEELRIGEGGFGCVYRAVMRNTTY-AVKRLKEEADLEWTMVKQSFLTEV 260 Query: 528 SVISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDILH 650 +SR +H + VD GYC E L Y F GSL D LH Sbjct: 261 EQLSRFRHPNIVDFAGYCAESGLYCLVYGFLPNGSLEDQLH 301
>NAK_ARATH (P43293) Probable serine/threonine-protein kinase NAK (EC 2.7.11.1)| Length = 389 Score = 70.1 bits (170), Expect = 5e-12 Identities = 40/121 (33%), Positives = 66/121 (54%), Gaps = 10/121 (8%) Frame = +3 Query: 315 QGKAPPSIQVPELSFDELKEKTDDFGSKALVGEGSYGRVYYAVLEN----------GTHV 464 +G+ + + S ELK T +F ++VGEG +G V+ ++ G + Sbjct: 44 EGEILQNANLKNFSLSELKSATRNFRPDSVVGEGGFGCVFKGWIDESSLAPSKPGTGIVI 103 Query: 465 AVKKLDTSADPEPDNEFIAQVSVISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDI 644 AVK+L+ + E++A+++ + +L H + V L+GYCLE + RLL YEF T GSL + Sbjct: 104 AVKRLNQEGF-QGHREWLAEINYLGQLDHPNLVKLIGYCLEEEHRLLVYEFMTRGSLENH 162 Query: 645 L 647 L Sbjct: 163 L 163
>CLV1_ARATH (Q9SYQ8) Receptor protein kinase CLAVATA1 precursor (EC 2.7.11.1)| Length = 980 Score = 70.1 bits (170), Expect = 5e-12 Identities = 36/104 (34%), Positives = 56/104 (53%), Gaps = 4/104 (3%) Frame = +3 Query: 354 SFDELKEKTDD----FGSKALVGEGSYGRVYYAVLENGTHVAVKKLDTSADPEPDNEFIA 521 +F +L K++D + ++G+G G VY + N VA+K+L D+ F A Sbjct: 677 AFQKLDFKSEDVLECLKEENIIGKGGAGIVYRGSMPNNVDVAIKRLVGRGTGRSDHGFTA 736 Query: 522 QVSVISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDILHG 653 ++ + R++H H V LLGY D LL YE+ GSL ++LHG Sbjct: 737 EIQTLGRIRHRHIVRLLGYVANKDTNLLLYEYMPNGSLGELLHG 780
>APK1B_ARATH (P46573) Protein kinase APK1B, chloroplast precursor (EC 2.7.11.1)| Length = 412 Score = 68.6 bits (166), Expect = 2e-11 Identities = 40/121 (33%), Positives = 65/121 (53%), Gaps = 10/121 (8%) Frame = +3 Query: 315 QGKAPPSIQVPELSFDELKEKTDDFGSKALVGEGSYGRVYYAVLEN----------GTHV 464 +G+ S + +F ELK T +F +++GEG +G V+ ++ G + Sbjct: 45 EGEILQSPNLKSFTFAELKAATRNFRPDSVLGEGGFGSVFKGWIDEQTLTASKPGTGVVI 104 Query: 465 AVKKLDTSADPEPDNEFIAQVSVISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDI 644 AVKKL+ + E++A+V+ + + H + V L+GYCLE + RLL YEF GSL + Sbjct: 105 AVKKLNQDGW-QGHQEWLAEVNYLGQFSHPNLVKLIGYCLEDEHRLLVYEFMPRGSLENH 163 Query: 645 L 647 L Sbjct: 164 L 164
>IRAK1_HUMAN (P51617) Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1)| (IRAK-1) Length = 712 Score = 68.2 bits (165), Expect = 2e-11 Identities = 39/99 (39%), Positives = 53/99 (53%), Gaps = 3/99 (3%) Frame = +3 Query: 363 ELKEKTDDFGSKALVGEGSYGRVYYAVLENGTHVAVKKLDTSADPE---PDNEFIAQVSV 533 E+ T +F + +GEG +G VY AV+ N T AVK+L +AD E F+ +V Sbjct: 204 EISRGTHNFSEELKIGEGGFGCVYRAVMRN-TVYAVKRLKENADLEWTAVKQSFLTEVEQ 262 Query: 534 ISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDILH 650 +SR +H + VD GYC + L Y F GSL D LH Sbjct: 263 LSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLH 301
>KPRO_MAIZE (P17801) Putative receptor protein kinase ZmPK1 precursor (EC| 2.7.11.1) Length = 817 Score = 68.2 bits (165), Expect = 2e-11 Identities = 42/98 (42%), Positives = 56/98 (57%) Frame = +3 Query: 354 SFDELKEKTDDFGSKALVGEGSYGRVYYAVLENGTHVAVKKLDTSADPEPDNEFIAQVSV 533 S+ EL + T F K +G G G VY VLE+ HVAVKKL+ + F A++SV Sbjct: 525 SYRELVKATRKF--KVELGRGESGTVYKGVLEDDRHVAVKKLENVRQGK--EVFQAELSV 580 Query: 534 ISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDIL 647 I R+ H + V + G+C EG RLL E+ GSL +IL Sbjct: 581 IGRINHMNLVRIWGFCSEGSHRLLVSEYVENGSLANIL 618
>BAK1_ARATH (Q94F62) BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1| precursor (EC 2.7.11.1) (BRI1-associated receptor kinase 1) (Somatic embryogenesis receptor-like kinase 3) Length = 615 Score = 67.8 bits (164), Expect = 3e-11 Identities = 35/103 (33%), Positives = 57/103 (55%) Frame = +3 Query: 339 QVPELSFDELKEKTDDFGSKALVGEGSYGRVYYAVLENGTHVAVKKLDTSADPEPDNEFI 518 Q+ S EL+ +D+F +K ++G G +G+VY L +GT VAVK+L + +F Sbjct: 273 QLKRFSLRELQVASDNFSNKNILGRGGFGKVYKGRLADGTLVAVKRLKEERTQGGELQFQ 332 Query: 519 AQVSVISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDIL 647 +V +IS H + + L G+C+ +RLL Y + GS+ L Sbjct: 333 TEVEMISMAVHRNLLRLRGFCMTPTERLLVYPYMANGSVASCL 375
>CX32_ARATH (P27450) Probable serine/threonine-protein kinase Cx32, chloroplast| precursor (EC 2.7.11.1) Length = 419 Score = 67.4 bits (163), Expect = 4e-11 Identities = 48/163 (29%), Positives = 75/163 (46%), Gaps = 21/163 (12%) Frame = +3 Query: 222 AHVDTPYEENGDEFPHSPERANGNGFTQ-----------IGDQGKAPPSIQVPELSFDEL 368 +H T NG EF + + Q I D GK S + +F +L Sbjct: 20 SHATTNNHSNGTEFSSTTGATTNSSVGQQSQFSDISTGIISDSGKLLESPNLKVYNFLDL 79 Query: 369 KEKTDDFGSKALVGEGSYGRVYYAVLE----------NGTHVAVKKLDTSADPEPDNEFI 518 K T +F +++G+G +G+VY ++ +G VA+K+L+ S + E+ Sbjct: 80 KTATKNFKPDSMLGQGGFGKVYRGWVDATTLAPSRVGSGMIVAIKRLN-SESVQGFAEWR 138 Query: 519 AQVSVISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDIL 647 ++V+ + L H + V LLGYC E + LL YEF GSL L Sbjct: 139 SEVNFLGMLSHRNLVKLLGYCREDKELLLVYEFMPKGSLESHL 181
>RLK5_ARATH (P47735) Receptor-like protein kinase 5 precursor (EC 2.7.11.1)| Length = 999 Score = 65.1 bits (157), Expect = 2e-10 Identities = 42/111 (37%), Positives = 56/111 (50%), Gaps = 9/111 (8%) Frame = +3 Query: 348 ELSFDELKEKTDDFGSKALVGEGSYGRVYYAVLENGTHVAVKKLDTSADPEPD------- 506 +L F E E D K ++G GS G+VY L G VAVKKL+ S D Sbjct: 671 KLHFSE-HEIADCLDEKNVIGFGSSGKVYKVELRGGEVVAVKKLNKSVKGGDDEYSSDSL 729 Query: 507 --NEFIAQVSVISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDILHG 653 + F A+V + ++H+ V L C GD +LL YE+ GSL D+LHG Sbjct: 730 NRDVFAAEVETLGTIRHKSIVRLWCCCSSGDCKLLVYEYMPNGSLADVLHG 780
>IRAK4_HUMAN (Q9NWZ3) Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1)| (IRAK-4) (NY-REN-64 antigen) Length = 460 Score = 63.2 bits (152), Expect = 7e-10 Identities = 45/134 (33%), Positives = 65/134 (48%), Gaps = 22/134 (16%) Frame = +3 Query: 312 DQGKAPPSIQVPE-------------LSFDELKEKTDDFGSKAL------VGEGSYGRVY 434 +Q PP PE SF ELK T++F + + +GEG +G VY Sbjct: 142 EQSYMPPDSSSPENKSLEVSDTRFHSFSFYELKNVTNNFDERPISVGGNKMGEGGFGVVY 201 Query: 435 YAVLENGTHVAVKKLDTSAD---PEPDNEFIAQVSVISRLKHEHFVDLLGYCLEGDQRLL 605 + N T VAVKKL D E +F ++ V+++ +HE+ V+LLG+ +GD L Sbjct: 202 KGYVNNTT-VAVKKLAAMVDITTEELKQQFDQEIKVMAKCQHENLVELLGFSSDGDDLCL 260 Query: 606 AYEFATMGSLHDIL 647 Y + GSL D L Sbjct: 261 VYVYMPNGSLLDRL 274
>SIRK_ARATH (O64483) Senescence-induced receptor-like serine/threonine-protein| kinase precursor (FLG22-induced receptor-like kinase 1) Length = 876 Score = 58.9 bits (141), Expect = 1e-08 Identities = 34/99 (34%), Positives = 58/99 (58%) Frame = +3 Query: 357 FDELKEKTDDFGSKALVGEGSYGRVYYAVLENGTHVAVKKLDTSADPEPDNEFIAQVSVI 536 + E+ T++F + ++G+G +G+VY+ V+ NG VAVK L + + EF A+V ++ Sbjct: 566 YSEVVNITNNF--ERVIGKGGFGKVYHGVI-NGEQVAVKVLSEES-AQGYKEFRAEVDLL 621 Query: 537 SRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDILHG 653 R+ H + L+GYC E + +L YE+ +L D L G Sbjct: 622 MRVHHTNLTSLVGYCNEINHMVLIYEYMANENLGDYLAG 660
>RPK1_IPONI (P93194) Receptor-like protein kinase precursor (EC 2.7.11.1)| Length = 1109 Score = 58.5 bits (140), Expect = 2e-08 Identities = 28/97 (28%), Positives = 52/97 (53%) Frame = +3 Query: 360 DELKEKTDDFGSKALVGEGSYGRVYYAVLENGTHVAVKKLDTSADPEPDNEFIAQVSVIS 539 +++ E T++ K ++G+G++G +Y A L AVKKL + + ++ I Sbjct: 807 NKVLEATENLNDKYVIGKGAHGTIYKATLSPDKVYAVKKLVFTGIKNGSVSMVREIETIG 866 Query: 540 RLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDILH 650 +++H + + L + L + L+ Y + GSLHDILH Sbjct: 867 KVRHRNLIKLEEFWLRKEYGLILYTYMENGSLHDILH 903
>IRAK4_MOUSE (Q8R4K2) Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1)| (IRAK-4) Length = 459 Score = 56.6 bits (135), Expect = 6e-08 Identities = 38/107 (35%), Positives = 56/107 (52%), Gaps = 9/107 (8%) Frame = +3 Query: 354 SFDELKEKTDDFGSKAL------VGEGSYGRVYYAVLENGTHVAVKKLDTSAD---PEPD 506 SF ELK T++F + +GEG +G VY + N T VAVKKL + E Sbjct: 169 SFHELKSITNNFDEQPASAGGNRMGEGGFGVVYKGCVNN-TIVAVKKLGAMVEISTEELK 227 Query: 507 NEFIAQVSVISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDIL 647 +F ++ V++ +HE+ V+LLG+ + D L Y + GSL D L Sbjct: 228 QQFDQEIKVMATCQHENLVELLGFSSDSDNLCLVYAYMPNGSLLDRL 274
>NTRK2_RAT (Q63604) BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB/GP95-TrkB) (Trk-B) Length = 821 Score = 52.0 bits (123), Expect = 2e-06 Identities = 31/94 (32%), Positives = 50/94 (53%), Gaps = 8/94 (8%) Frame = +3 Query: 396 KALVGEGSYGRVYYAVLEN------GTHVAVKKLDTSADPEPDNEFIAQVSVISRLKHEH 557 K +GEG++G+V+ A N VAVK L ++D +F + +++ L+HEH Sbjct: 540 KRELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKDASD-NARKDFHREAELLTNLQHEH 598 Query: 558 FVDLLGYCLEGDQRLLAYEFATMGSLHDIL--HG 653 V G C+EGD ++ +E+ G L+ L HG Sbjct: 599 IVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHG 632
>NTRK2_MOUSE (P15209) BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB/GP95-TrkB) (Trk-B) Length = 821 Score = 52.0 bits (123), Expect = 2e-06 Identities = 31/94 (32%), Positives = 50/94 (53%), Gaps = 8/94 (8%) Frame = +3 Query: 396 KALVGEGSYGRVYYAVLEN------GTHVAVKKLDTSADPEPDNEFIAQVSVISRLKHEH 557 K +GEG++G+V+ A N VAVK L ++D +F + +++ L+HEH Sbjct: 540 KRELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKDASD-NARKDFHREAELLTNLQHEH 598 Query: 558 FVDLLGYCLEGDQRLLAYEFATMGSLHDIL--HG 653 V G C+EGD ++ +E+ G L+ L HG Sbjct: 599 IVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHG 632
>NTRK2_CHICK (Q91987) BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (Trk-B) Length = 818 Score = 52.0 bits (123), Expect = 2e-06 Identities = 31/94 (32%), Positives = 50/94 (53%), Gaps = 8/94 (8%) Frame = +3 Query: 396 KALVGEGSYGRVYYAVLEN------GTHVAVKKLDTSADPEPDNEFIAQVSVISRLKHEH 557 K +GEG++G+V+ A N VAVK L ++D +F + +++ L+HEH Sbjct: 537 KRELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKDASD-NARKDFHREAELLTNLQHEH 595 Query: 558 FVDLLGYCLEGDQRLLAYEFATMGSLHDIL--HG 653 V G C+EGD ++ +E+ G L+ L HG Sbjct: 596 IVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHG 629
>NTRK2_HUMAN (Q16620) BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB) (Trk-B) Length = 822 Score = 52.0 bits (123), Expect = 2e-06 Identities = 31/94 (32%), Positives = 50/94 (53%), Gaps = 8/94 (8%) Frame = +3 Query: 396 KALVGEGSYGRVYYAVLEN------GTHVAVKKLDTSADPEPDNEFIAQVSVISRLKHEH 557 K +GEG++G+V+ A N VAVK L ++D +F + +++ L+HEH Sbjct: 541 KRELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKDASD-NARKDFHREAELLTNLQHEH 599 Query: 558 FVDLLGYCLEGDQRLLAYEFATMGSLHDIL--HG 653 V G C+EGD ++ +E+ G L+ L HG Sbjct: 600 IVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHG 633
>SRK2_SPOLA (P42688) Tyrosine-protein kinase SRK2 (EC 2.7.10.2) (Fragment)| Length = 362 Score = 51.6 bits (122), Expect = 2e-06 Identities = 31/108 (28%), Positives = 48/108 (44%) Frame = +3 Query: 330 PSIQVPELSFDELKEKTDDFGSKALVGEGSYGRVYYAVLENGTHVAVKKLDTSADPEPDN 509 P I + + D + D +G G +G VY + N T VAVK L A Sbjct: 76 PQIDLSHKTKDMWEISRDSITLIRKLGAGQFGEVYQGLWNNSTPVAVKTL--KAGTMQPA 133 Query: 510 EFIAQVSVISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDILHG 653 F+A+ ++ +L+H + L C +G+ + E + GSL D L G Sbjct: 134 AFLAEAQIMKKLRHPKLIQLYAVCTQGEPVYIITELMSKGSLLDYLQG 181
>ROR1_DROME (Q24488) Tyrosine-protein kinase transmembrane receptor Ror| precursor (EC 2.7.10.1) (dRor) Length = 685 Score = 51.6 bits (122), Expect = 2e-06 Identities = 27/85 (31%), Positives = 47/85 (55%), Gaps = 4/85 (4%) Frame = +3 Query: 405 VGEGSYGRVYYAVL----ENGTHVAVKKLDTSADPEPDNEFIAQVSVISRLKHEHFVDLL 572 +GEG++G+VY L + VA+K L +A + +F ++ +IS LKH++ V +L Sbjct: 416 LGEGAFGKVYKGQLLQPNKTTITVAIKALKENASVKTQQDFKREIELISDLKHQNIVCIL 475 Query: 573 GYCLEGDQRLLAYEFATMGSLHDIL 647 G L + + +E+ G LH+ L Sbjct: 476 GVVLNKEPYCMLFEYMANGDLHEFL 500
>M3K10_HUMAN (Q02779) Mitogen-activated protein kinase kinase kinase 10 (EC| 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST) Length = 954 Score = 51.6 bits (122), Expect = 2e-06 Identities = 39/114 (34%), Positives = 58/114 (50%), Gaps = 4/114 (3%) Frame = +3 Query: 324 APPSIQVP-ELSFDELKEKTDDFGSKALVGEGSYGRVYYAVLENGTHVAVK--KLDTSAD 494 AP +Q+P E+ F EL+ + ++G G +G+VY A L G VAVK +LD D Sbjct: 83 APAGLQLPQEIPFHELQ-------LEEIIGVGGFGKVYRA-LWRGEEVAVKAARLDPEKD 134 Query: 495 PEPDNEFIAQVS-VISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDILHG 653 P E + Q + + L+H + + L G CL L E+A G+L +L G Sbjct: 135 PAVTAEQVCQEARLFGALQHPNIIALRGACLNPPHLCLVMEYARGGALSRVLAG 188
>INSRR_CAVPO (P14617) Insulin receptor-related protein precursor (EC 2.7.10.1)| (IRR) (IR-related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain] Length = 1300 Score = 51.6 bits (122), Expect = 2e-06 Identities = 35/125 (28%), Positives = 56/125 (44%), Gaps = 6/125 (4%) Frame = +3 Query: 279 RANGNGFTQIGDQGKAPPSIQVPELSFDELKEKTDDFGSKALVGEGSYGRVYYAVL---- 446 + NG +T + + + + +P DE + + +G+GS+G VY V Sbjct: 947 KRNGTLYTSVNPEYLSASDMYIP----DEWEVPREQISIIRELGQGSFGMVYEGVAKGLE 1002 Query: 447 --ENGTHVAVKKLDTSADPEPDNEFIAQVSVISRLKHEHFVDLLGYCLEGDQRLLAYEFA 620 E T VA+K ++ A P EF+ + SV+ + H V LLG +G L+ E Sbjct: 1003 AGEESTPVALKTVNELASPRERIEFLKEASVMKAFQCHHVVRLLGVVSQGQPTLVIMELM 1062 Query: 621 TMGSL 635 T G L Sbjct: 1063 TRGDL 1067
>ABL1_MOUSE (P00520) Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2)| (p150) (c-ABL) (Abelson murine leukemia viral oncogene homolog 1) Length = 1123 Score = 51.6 bits (122), Expect = 2e-06 Identities = 35/107 (32%), Positives = 51/107 (47%), Gaps = 1/107 (0%) Frame = +3 Query: 330 PSIQVPELSFDELKEKTDDFGSKALVGEGSYGRVYYAVLEN-GTHVAVKKLDTSADPEPD 506 P+I ++D+ + + D K +G G YG VY V + VAVK L D Sbjct: 223 PTIYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTL--KEDTMEV 280 Query: 507 NEFIAQVSVISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDIL 647 EF+ + +V+ +KH + V LLG C + EF T G+L D L Sbjct: 281 EEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYL 327
>STK4_HUMAN (Q13043) Serine/threonine-protein kinase 4 (EC 2.7.11.1)| (STE20-like kinase MST1) (MST-1) (Mammalian STE20-like protein kinase 1) (Serine/threonine-protein kinase Krs-2) Length = 487 Score = 51.6 bits (122), Expect = 2e-06 Identities = 34/113 (30%), Positives = 58/113 (51%), Gaps = 2/113 (1%) Frame = +3 Query: 315 QGKAPPSIQVPELSFDELKEKTDD-FGSKALVGEGSYGRVYYAV-LENGTHVAVKKLDTS 488 Q + PP Q+ +L D L ++ ++ F +GEGSYG VY A+ E G VA+K++ Sbjct: 5 QLRNPPRRQLKKLDEDSLTKQPEEVFDVLEKLGEGSYGSVYKAIHKETGQIVAIKQVPVE 64 Query: 489 ADPEPDNEFIAQVSVISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDIL 647 +D + E I ++S++ + H V G + + E+ GS+ DI+ Sbjct: 65 SDLQ---EIIKEISIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDII 114
>ABL_MLVAB (P00521) Tyrosine-protein kinase transforming protein Abl (EC| 2.7.10.2) (V-abl) Length = 746 Score = 51.6 bits (122), Expect = 2e-06 Identities = 35/107 (32%), Positives = 51/107 (47%), Gaps = 1/107 (0%) Frame = +3 Query: 330 PSIQVPELSFDELKEKTDDFGSKALVGEGSYGRVYYAVLEN-GTHVAVKKLDTSADPEPD 506 P+I ++D+ + + D K +G G YG VY V + VAVK L D Sbjct: 109 PTIYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTL--KEDTMEV 166 Query: 507 NEFIAQVSVISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDIL 647 EF+ + +V+ +KH + V LLG C + EF T G+L D L Sbjct: 167 EEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYL 213
>ABL_FSVHY (P10447) Tyrosine-protein kinase transforming protein Abl (EC| 2.7.10.2) (V-abl) Length = 439 Score = 51.2 bits (121), Expect = 3e-06 Identities = 34/107 (31%), Positives = 51/107 (47%), Gaps = 1/107 (0%) Frame = +3 Query: 330 PSIQVPELSFDELKEKTDDFGSKALVGEGSYGRVYYAVLEN-GTHVAVKKLDTSADPEPD 506 P++ ++D+ + + D K +G G YG VY V + VAVK L D Sbjct: 172 PTVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTL--KEDTMEV 229 Query: 507 NEFIAQVSVISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDIL 647 EF+ + +V+ +KH + V LLG C + EF T G+L D L Sbjct: 230 EEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYL 276
>ABL1_HUMAN (P00519) Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2)| (p150) (c-ABL) (Abelson murine leukemia viral oncogene homolog 1) Length = 1130 Score = 51.2 bits (121), Expect = 3e-06 Identities = 34/107 (31%), Positives = 51/107 (47%), Gaps = 1/107 (0%) Frame = +3 Query: 330 PSIQVPELSFDELKEKTDDFGSKALVGEGSYGRVYYAVLEN-GTHVAVKKLDTSADPEPD 506 P++ ++D+ + + D K +G G YG VY V + VAVK L D Sbjct: 223 PTVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTL--KEDTMEV 280 Query: 507 NEFIAQVSVISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDIL 647 EF+ + +V+ +KH + V LLG C + EF T G+L D L Sbjct: 281 EEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYL 327
>BYR2_SCHPO (P28829) Protein kinase byr2 (EC 2.7.11.25) (Protein kinase ste8)| (MAPK kinase kinase) (MAPKKK) Length = 659 Score = 51.2 bits (121), Expect = 3e-06 Identities = 45/165 (27%), Positives = 73/165 (44%), Gaps = 25/165 (15%) Frame = +3 Query: 228 VDTPYEENGDE----FPHSPERANGNGFTQIGDQGKAPPSIQVPEL---------SFDEL 368 V+ Y+ NG+E + E A+GN G +P I+ P + L Sbjct: 324 VEPLYQSNGNEKSSKYNVFSESAHGNHQVLSFSPGSSPSFIEQPSPISPTSTTSEDTNTL 383 Query: 369 KEKTDDFGSK----ALVGEGSYGRVYYAV-LENGTHVAVKKLDTSADPEPDNE------- 512 +E TDD K AL+G GS+G+VY + +G +AVK++ + E + Sbjct: 384 EEDTDDQSIKWIRGALIGSGSFGQVYLGMNASSGELMAVKQVILDSVSESKDRHAKLLDA 443 Query: 513 FIAQVSVISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDIL 647 +++++ L HEH V LG L D + E+ GS+ +L Sbjct: 444 LAGEIALLQELSHEHIVQYLGSNLNSDHLNIFLEYVPGGSVAGLL 488
>ROS_CHICK (P08941) Proto-oncogene tyrosine-protein kinase ROS precursor (EC| 2.7.10.1) (c-ros-1) Length = 2311 Score = 50.8 bits (120), Expect = 3e-06 Identities = 31/98 (31%), Positives = 47/98 (47%), Gaps = 7/98 (7%) Frame = +3 Query: 381 DDFGSKALVGEGSYGRVYYA----VLENGT---HVAVKKLDTSADPEPDNEFIAQVSVIS 539 D L+G G++G VY +L +G+ VAVK L A + +EF+ + ++S Sbjct: 1959 DKLNLHKLLGSGAFGEVYEGTALDILADGSGESRVAVKTLKRGATDQEKSEFLKEAHLMS 2018 Query: 540 RLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDILHG 653 + H H + LLG CL + + L E G L L G Sbjct: 2019 KFDHPHILKLLGVCLLNEPQYLILELMEGGDLLSYLRG 2056
>RET_HUMAN (P07949) Proto-oncogene tyrosine-protein kinase receptor ret| precursor (EC 2.7.10.1) (C-ret) Length = 1114 Score = 50.8 bits (120), Expect = 3e-06 Identities = 36/114 (31%), Positives = 54/114 (47%), Gaps = 11/114 (9%) Frame = +3 Query: 339 QVPELSFDELKEKTDDFGSKALV-----GEGSYGRVYYAVL------ENGTHVAVKKLDT 485 QV +F L++ +F K LV GEG +G+V A T VAVK L Sbjct: 703 QVSVDAFKILEDPKWEFPRKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKE 762 Query: 486 SADPEPDNEFIAQVSVISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDIL 647 +A P + +++ +V+ ++ H H + L G C + LL E+A GSL L Sbjct: 763 NASPSELRDLLSEFNVLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFL 816
>ROS_AVISU (P00529) Tyrosine-protein kinase transforming protein ros (EC| 2.7.10.1) Length = 402 Score = 50.8 bits (120), Expect = 3e-06 Identities = 31/98 (31%), Positives = 47/98 (47%), Gaps = 7/98 (7%) Frame = +3 Query: 381 DDFGSKALVGEGSYGRVYYA----VLENGT---HVAVKKLDTSADPEPDNEFIAQVSVIS 539 D L+G G++G VY +L +G+ VAVK L A + +EF+ + ++S Sbjct: 96 DKLNLHKLLGSGAFGEVYEGTALDILADGSGESRVAVKTLKRGATDQEKSEFLKEAHLMS 155 Query: 540 RLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDILHG 653 + H H + LLG CL + + L E G L L G Sbjct: 156 KFDHPHILKLLGVCLLNEPQYLILELMEGGDLLSYLRG 193
>M3K7_HUMAN (O43318) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1) Length = 606 Score = 50.1 bits (118), Expect = 6e-06 Identities = 36/124 (29%), Positives = 68/124 (54%) Frame = +3 Query: 282 ANGNGFTQIGDQGKAPPSIQVPELSFDELKEKTDDFGSKALVGEGSYGRVYYAVLENGTH 461 A+ + + G+ +AP + L+F+E+ K + + +VG G++G V A Sbjct: 7 ASSSSSSSAGEMIEAPSQV----LNFEEIDYK--EIEVEEVVGRGAFGVVCKAKWR-AKD 59 Query: 462 VAVKKLDTSADPEPDNEFIAQVSVISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHD 641 VA+K++++ ++ + FI ++ +SR+ H + V L G CL + L E+A GSL++ Sbjct: 60 VAIKQIESESERKA---FIVELRQLSRVNHPNIVKLYGACL--NPVCLVMEYAEGGSLYN 114 Query: 642 ILHG 653 +LHG Sbjct: 115 VLHG 118
>M3K7_DROME (Q9V3Q6) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (TGF-beta-activated kinase 1) (dTAK1) Length = 678 Score = 49.7 bits (117), Expect = 8e-06 Identities = 39/103 (37%), Positives = 51/103 (49%), Gaps = 3/103 (2%) Frame = +3 Query: 354 SFDELKEKTDDFGSKAL---VGEGSYGRVYYAVLENGTHVAVKKLDTSADPEPDNEFIAQ 524 S D L+ DF L VG GSYG V AV + VAVK+ SA+ + + + Sbjct: 5 SLDALQAAYVDFSEITLREKVGHGSYGVVCKAVWRDKL-VAVKEFFASAEQK---DIEKE 60 Query: 525 VSVISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDILHG 653 V +SR+KH + + L G L EFA GSLH+ LHG Sbjct: 61 VKQLSRVKHPNIIALHGISSYQQATYLIMEFAEGGSLHNFLHG 103
>TIE1_HUMAN (P35590) Tyrosine-protein kinase receptor Tie-1 precursor (EC| 2.7.10.1) Length = 1138 Score = 49.7 bits (117), Expect = 8e-06 Identities = 32/110 (29%), Positives = 57/110 (51%), Gaps = 4/110 (3%) Frame = +3 Query: 330 PSIQVPELSFDELKEKTDDFGSKALVGEGSYGRVYYAVLENG---THVAVKKLDTSADPE 500 P +Q LS+ L+ +D + L+GEG++G+V A+++ + A+K L A Sbjct: 822 PKLQPEPLSYPVLE--WEDITFEDLIGEGNFGQVIRAMIKKDGLKMNAAIKMLKEYASEN 879 Query: 501 PDNEFIAQVSVISRLKHE-HFVDLLGYCLEGDQRLLAYEFATMGSLHDIL 647 +F ++ V+ +L H + ++LLG C +A E+A G+L D L Sbjct: 880 DHRDFAGELEVLCKLGHHPNIINLLGACKNRGYLYIAIEYAPYGNLLDFL 929
>CTR1_ARATH (Q05609) Serine/threonine-protein kinase CTR1 (EC 2.7.11.1)| Length = 821 Score = 49.7 bits (117), Expect = 8e-06 Identities = 32/101 (31%), Positives = 54/101 (53%), Gaps = 1/101 (0%) Frame = +3 Query: 351 LSFDELKEKTDDFGSKALVGEGSYGRVYYAVLENGTHVAVKKL-DTSADPEPDNEFIAQV 527 L D++ D K +G GS+G V+ A +G+ VAVK L + E NEF+ +V Sbjct: 539 LDGDDMDIPWCDLNIKEKIGAGSFGTVHRAEW-HGSDVAVKILMEQDFHAERVNEFLREV 597 Query: 528 SVISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDILH 650 +++ RL+H + V +G + + E+ + GSL+ +LH Sbjct: 598 AIMKRLRHPNIVLFMGAVTQPPNLSIVTEYLSRGSLYRLLH 638
>DDR2_MOUSE (Q62371) Discoidin domain-containing receptor 2 precursor (EC| 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen) Length = 854 Score = 49.3 bits (116), Expect = 1e-05 Identities = 43/166 (25%), Positives = 69/166 (41%), Gaps = 23/166 (13%) Frame = +3 Query: 219 CAHVDTPYEENGDE-FPHSPERANGNGFTQIGDQGKAPPSIQVPELSFDELKEKTDDFGS 395 C+ V P + NG E PH E N G P++ + LS ++ ++F Sbjct: 503 CSGVVKPAQPNGPEGVPHYAEADIVNLQGVTGGNTYCVPAVTMDLLSGKDVA--VEEFPR 560 Query: 396 KAL-----VGEGSYGRVYYAVLENGTH-----------------VAVKKLDTSADPEPDN 509 K L +GEG +G V+ +E VAVK L A+ N Sbjct: 561 KLLAFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARN 620 Query: 510 EFIAQVSVISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDIL 647 +F+ ++ ++SRLK + + LL C+ D + E+ G L+ L Sbjct: 621 DFLKEIKIMSRLKDPNIIRLLAVCITEDPLCMITEYMENGDLNQFL 666
>ITK_MOUSE (Q03526) Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2)| (T-cell-specific kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (Kinase TLK) Length = 625 Score = 48.9 bits (115), Expect = 1e-05 Identities = 29/81 (35%), Positives = 38/81 (46%) Frame = +3 Query: 405 VGEGSYGRVYYAVLENGTHVAVKKLDTSADPEPDNEFIAQVSVISRLKHEHFVDLLGYCL 584 +G G +G V+ N VA+K + A E D FI + V+ +L H V L G CL Sbjct: 374 IGSGQFGLVHLGYWLNKDKVAIKTIQEGAMSEED--FIEEAEVMMKLSHPKLVQLYGVCL 431 Query: 585 EGDQRLLAYEFATMGSLHDIL 647 E L +EF G L D L Sbjct: 432 EQAPICLVFEFMEHGCLSDYL 452
>DDR2_HUMAN (Q16832) Discoidin domain-containing receptor 2 precursor (EC| 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen) Length = 855 Score = 48.9 bits (115), Expect = 1e-05 Identities = 42/166 (25%), Positives = 70/166 (42%), Gaps = 23/166 (13%) Frame = +3 Query: 219 CAHVDTPYEENGDE-FPHSPERANGNGFTQIGDQGKAPPSIQVPELSFDELKEKTDDFGS 395 C+ V P + +G E PH E N G + P++ + LS ++ ++F Sbjct: 503 CSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVA--VEEFPR 560 Query: 396 KAL-----VGEGSYGRVYYAVLENGTH-----------------VAVKKLDTSADPEPDN 509 K L +GEG +G V+ +E VAVK L A+ N Sbjct: 561 KLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARN 620 Query: 510 EFIAQVSVISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDIL 647 +F+ ++ ++SRLK + + LL C+ D + E+ G L+ L Sbjct: 621 DFLKEIKIMSRLKDPNIIHLLSVCITDDPLCMITEYMENGDLNQFL 666
>NTRK3_PIG (P24786) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (GP145-TrkC) (Trk-C) Length = 825 Score = 48.5 bits (114), Expect = 2e-05 Identities = 31/100 (31%), Positives = 49/100 (49%), Gaps = 7/100 (7%) Frame = +3 Query: 375 KTDDFGSKALVGEGSYGRVYYAVLENGTHVAVKKL---DTSADPE--PDNEFIAQVSVIS 539 K D K +GEG++G+V+ A N + VK L DP +F + +++ Sbjct: 534 KRRDIVLKRELGEGAFGKVFLAECYNLSPTKVKMLVAVKALKDPTLAARKDFQREAELLT 593 Query: 540 RLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDIL--HG 653 L+HEH V G C +GD ++ +E+ G L+ L HG Sbjct: 594 NLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHG 633
>DDR1_MOUSE (Q03146) Epithelial discoidin domain-containing receptor 1| precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (Protei Length = 911 Score = 48.1 bits (113), Expect = 2e-05 Identities = 36/130 (27%), Positives = 55/130 (42%), Gaps = 17/130 (13%) Frame = +3 Query: 309 GDQGKAPPSIQVPELSFDELKEKTDDFGSKALVGEGSYGRVYYAVLEN-----------G 455 G G PP + P KEK +GEG +G V+ +E+ Sbjct: 592 GAVGDGPPRVDFPRSRL-RFKEK---------LGEGQFGEVHLCEVEDPQDLVSSDFPIS 641 Query: 456 TH------VAVKKLDTSADPEPDNEFIAQVSVISRLKHEHFVDLLGYCLEGDQRLLAYEF 617 H VAVK L A N+F+ +V ++SRLK + + LLG C++ D + ++ Sbjct: 642 VHKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDY 701 Query: 618 ATMGSLHDIL 647 G L+ L Sbjct: 702 MENGDLNQFL 711
>RET_MOUSE (P35546) Proto-oncogene tyrosine-protein kinase receptor ret| precursor (EC 2.7.10.1) (C-ret) Length = 1115 Score = 48.1 bits (113), Expect = 2e-05 Identities = 35/114 (30%), Positives = 53/114 (46%), Gaps = 11/114 (9%) Frame = +3 Query: 339 QVPELSFDELKEKTDDFGSKALV-----GEGSYGRVYYAVL------ENGTHVAVKKLDT 485 QVP SF ++ +F K LV GEG +G+V A T VAVK L Sbjct: 704 QVPVDSFKIPEDPKWEFPRKNLVLGKTLGEGEFGKVVKATAFRLKGRAGYTTVAVKMLKE 763 Query: 486 SADPEPDNEFIAQVSVISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDIL 647 +A + +++ +++ ++ H H + L G C + LL E+A GSL L Sbjct: 764 NASQSELRDLLSEFNLLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFL 817
>INSRR_HUMAN (P14616) Insulin receptor-related protein precursor (EC 2.7.10.1)| (IRR) (IR-related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain] Length = 1297 Score = 48.1 bits (113), Expect = 2e-05 Identities = 29/83 (34%), Positives = 41/83 (49%), Gaps = 6/83 (7%) Frame = +3 Query: 405 VGEGSYGRVYYAVL------ENGTHVAVKKLDTSADPEPDNEFIAQVSVISRLKHEHFVD 566 +G+GS+G VY + E T VA+K ++ A P EF+ + SV+ K H V Sbjct: 985 LGQGSFGMVYEGLARGLEAGEESTPVALKTVNELASPRECIEFLKEASVMKAFKCHHVVR 1044 Query: 567 LLGYCLEGDQRLLAYEFATMGSL 635 LLG +G L+ E T G L Sbjct: 1045 LLGVVSQGQPTLVIMELMTRGDL 1067
>ITK_HUMAN (Q08881) Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2)| (T-cell-specific kinase) (Tyrosine-protein kinase Lyk) (Kinase EMT) Length = 620 Score = 48.1 bits (113), Expect = 2e-05 Identities = 29/81 (35%), Positives = 38/81 (46%) Frame = +3 Query: 405 VGEGSYGRVYYAVLENGTHVAVKKLDTSADPEPDNEFIAQVSVISRLKHEHFVDLLGYCL 584 +G G +G V+ N VA+K + A E D FI + V+ +L H V L G CL Sbjct: 369 IGSGQFGLVHLGYWLNKDKVAIKTIREGAMSEED--FIEEAEVMMKLSHPKLVQLYGVCL 426 Query: 585 EGDQRLLAYEFATMGSLHDIL 647 E L +EF G L D L Sbjct: 427 EQAPICLVFEFMEHGCLSDYL 447
>IGF1R_BOVIN (Q05688) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] (F Length = 640 Score = 48.1 bits (113), Expect = 2e-05 Identities = 36/133 (27%), Positives = 56/133 (42%), Gaps = 6/133 (4%) Frame = +3 Query: 267 HSPERANGNGFTQIGDQGKAPPSIQVPELSFDELKEKTDDFGSKALVGEGSYGRVYYAVL 446 +S NG + + + + + VP DE + + +G+GS+G VY V Sbjct: 236 NSSRLGNGVLYASVNPEYFSAADVYVP----DEWEVAREKITMSRELGQGSFGMVYEGVA 291 Query: 447 ------ENGTHVAVKKLDTSADPEPDNEFIAQVSVISRLKHEHFVDLLGYCLEGDQRLLA 608 E T VA+K ++ +A EF+ + SV+ H V LLG +G L+ Sbjct: 292 KGVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVI 351 Query: 609 YEFATMGSLHDIL 647 E T G L L Sbjct: 352 MELMTRGDLKSYL 364
>ABL_DROME (P00522) Tyrosine-protein kinase Abl (EC 2.7.10.2) (Abelson| protein) (D-ash) Length = 1620 Score = 48.1 bits (113), Expect = 2e-05 Identities = 32/97 (32%), Positives = 47/97 (48%), Gaps = 1/97 (1%) Frame = +3 Query: 360 DELKEKTDDFGSKALVGEGSYGRVYYAVLEN-GTHVAVKKLDTSADPEPDNEFIAQVSVI 536 DE + D K +G G YG VY AV + G VAVK L D +F+ + +++ Sbjct: 362 DEWEICRTDIMMKHKLGGGQYGEVYEAVWKRYGNTVAVKTL--KEDTMALKDFLEEAAIM 419 Query: 537 SRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDIL 647 +KH + V L+G C + EF + G+L D L Sbjct: 420 KEMKHPNLVQLIGVCTREPPFYIITEFMSHGNLLDFL 456
>M3K7_MOUSE (Q62073) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1) Length = 579 Score = 47.8 bits (112), Expect = 3e-05 Identities = 35/112 (31%), Positives = 62/112 (55%), Gaps = 2/112 (1%) Frame = +3 Query: 324 APPSIQVPE--LSFDELKEKTDDFGSKALVGEGSYGRVYYAVLENGTHVAVKKLDTSADP 497 A I+ P L+F+E+ K + + +VG G++G V A VA+K++++ ++ Sbjct: 15 ASEMIEAPSQVLNFEEIDYK--EIEVEEVVGRGAFGVVCKAKWR-AKDVAIKQIESESER 71 Query: 498 EPDNEFIAQVSVISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDILHG 653 + FI ++ +SR+ H + V L G CL + L E+A GSL+++LHG Sbjct: 72 KA---FIVELRQLSRVNHPNIVKLYGACL--NPVCLVMEYAEGGSLYNVLHG 118
>NTRK1_RAT (P35739) High affinity nerve growth factor receptor precursor (EC| 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (p140-TrkA) (Slow nerve growth factor receptor) (Trk-A) Length = 799 Score = 47.8 bits (112), Expect = 3e-05 Identities = 34/102 (33%), Positives = 52/102 (50%), Gaps = 9/102 (8%) Frame = +3 Query: 375 KTDDFGSKALVGEGSYGRVYYAVLENGTH------VAVKKL-DTSADPEPDNEFIAQVSV 533 K D K +GEG++G+V+ A N + VAVK L +TS + D F + + Sbjct: 509 KRQDIILKWELGEGAFGKVFLAECYNLLNDQDKMLVAVKALKETSENARQD--FHREAEL 566 Query: 534 ISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDIL--HG 653 ++ L+H+H V G C EG L+ +E+ G L+ L HG Sbjct: 567 LTMLQHQHIVRFFGVCTEGGPLLMVFEYMRHGDLNRFLRSHG 608
>YSK4_HUMAN (Q56UN5) SPS1/STE20-related protein kinase YSK4 (EC 2.7.11.1)| (Regulated in COPD, protein kinase) Length = 1328 Score = 47.8 bits (112), Expect = 3e-05 Identities = 29/88 (32%), Positives = 48/88 (54%), Gaps = 5/88 (5%) Frame = +3 Query: 402 LVGEGSYGRVYYAVLENGTHVAVKK--LDTSADPEPDNEFIA---QVSVISRLKHEHFVD 566 ++G+G+YG VY + G +AVK+ LDTS + E+ +V ++ LKH + V Sbjct: 1066 ILGKGAYGTVYCGLTSQGQLIAVKQVALDTSNKLAAEKEYRKLQEEVDLLKALKHVNIVA 1125 Query: 567 LLGYCLEGDQRLLAYEFATMGSLHDILH 650 LG CL+ + + EF GS+ I++ Sbjct: 1126 YLGTCLQENTVSIFMEFVPGGSISSIIN 1153
>CDC15_YEAST (P27636) Cell division control protein 15 (EC 2.7.11.1)| Length = 974 Score = 47.8 bits (112), Expect = 3e-05 Identities = 25/92 (27%), Positives = 47/92 (51%) Frame = +3 Query: 372 EKTDDFGSKALVGEGSYGRVYYAVLENGTHVAVKKLDTSADPEPDNEFIAQVSVISRLKH 551 EK+ + K ++G GSYG VY A+ ++ V K + E N+ +A++S++ L H Sbjct: 20 EKSVQYHLKQVIGRGSYGVVYKAINKHTDQVVAIKEVVYENDEELNDIMAEISLLKNLNH 79 Query: 552 EHFVDLLGYCLEGDQRLLAYEFATMGSLHDIL 647 + V G+ + + + E+ GSL ++ Sbjct: 80 NNIVKYHGFIRKSYELYILLEYCANGSLRRLI 111
>YR831_MIMIV (Q7T6Y2) Putative serine/threonine-protein kinase/receptor R831| precursor (EC 2.7.11.1) Length = 1624 Score = 47.4 bits (111), Expect = 4e-05 Identities = 30/90 (33%), Positives = 46/90 (51%), Gaps = 1/90 (1%) Frame = +3 Query: 381 DDFGSKALVGEGSYGRVYYAVLENGTHVAVKKLDTSADPEPDN-EFIAQVSVISRLKHEH 557 D+ +G GSYG V+ + G VAVKK E EF A+++ +S LKH + Sbjct: 1362 DEISIGKQIGLGSYGIVFNGKWK-GVDVAVKKFVKQKLSETQLLEFRAEMAFLSELKHSN 1420 Query: 558 FVDLLGYCLEGDQRLLAYEFATMGSLHDIL 647 V +G C++ + E+ MG+L D+L Sbjct: 1421 IVTFIGACIKKPNICIVTEYMRMGNLRDVL 1450 Score = 46.6 bits (109), Expect = 6e-05 Identities = 24/82 (29%), Positives = 45/82 (54%), Gaps = 1/82 (1%) Frame = +3 Query: 405 VGEGSYGRVYYAVLENGTHVAVKKLDTS-ADPEPDNEFIAQVSVISRLKHEHFVDLLGYC 581 +G G YG VY ++ + GT VAVK + + + + F +V +++ L+H + V + Sbjct: 792 LGTGGYGEVYKSIWK-GTEVAVKLISSKHVSKDMERSFFEEVKIMTSLRHPNVVLFMAAS 850 Query: 582 LEGDQRLLAYEFATMGSLHDIL 647 + + EF ++GSL+D+L Sbjct: 851 TKSPNMCIVMEFMSLGSLYDLL 872
>SPK1_DUGTI (P42687) Tyrosine-protein kinase SPK-1 (EC 2.7.10.2)| Length = 497 Score = 47.4 bits (111), Expect = 4e-05 Identities = 34/123 (27%), Positives = 56/123 (45%), Gaps = 2/123 (1%) Frame = +3 Query: 285 NGNGFTQIGDQGKAPPSIQVPELSFDELKEKTDDFGSKALVGEGSYGRVYYAVLENGTHV 464 NG G T I P + Q P + F +++ ++ +G G +G V+ A V Sbjct: 187 NGIGNTHIPLTDPMPDNYQ-PPVHFQDIEINRENIEILNEIGRGFFGSVHRAKWGRSYEV 245 Query: 465 AVKKLDTSADPEPDNEFIAQVSVISRLKHEHFVDLLGYCLEGDQ--RLLAYEFATMGSLH 638 A K L +S +F+ + ++ +L+H V+LLG C E L+ E+ GSL Sbjct: 246 AAKMLQSSKAER--EKFVLEAKIMHKLRHRKIVELLGVCTEPQDMPMLIIVEYMKNGSLK 303 Query: 639 DIL 647 + L Sbjct: 304 EYL 306
>IGF1R_RAT (P24062) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] Length = 1370 Score = 47.4 bits (111), Expect = 4e-05 Identities = 36/128 (28%), Positives = 55/128 (42%), Gaps = 8/128 (6%) Frame = +3 Query: 288 GNG--FTQIGDQGKAPPSIQVPELSFDELKEKTDDFGSKALVGEGSYGRVYYAVL----- 446 GNG + + + + + VP DE + + +G+GS+G VY V Sbjct: 969 GNGVLYASVNPEYFSAADVYVP----DEWEVAREKITMNRELGQGSFGMVYEGVAKGVVK 1024 Query: 447 -ENGTHVAVKKLDTSADPEPDNEFIAQVSVISRLKHEHFVDLLGYCLEGDQRLLAYEFAT 623 E T VA+K ++ +A EF+ + SV+ H V LLG +G L+ E T Sbjct: 1025 DEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMT 1084 Query: 624 MGSLHDIL 647 G L L Sbjct: 1085 RGDLKSYL 1092
>IGF1R_HUMAN (P08069) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 recepto Length = 1367 Score = 47.4 bits (111), Expect = 4e-05 Identities = 36/128 (28%), Positives = 55/128 (42%), Gaps = 8/128 (6%) Frame = +3 Query: 288 GNG--FTQIGDQGKAPPSIQVPELSFDELKEKTDDFGSKALVGEGSYGRVYYAVL----- 446 GNG + + + + + VP DE + + +G+GS+G VY V Sbjct: 968 GNGVLYASVNPEYFSAADVYVP----DEWEVAREKITMSRELGQGSFGMVYEGVAKGVVK 1023 Query: 447 -ENGTHVAVKKLDTSADPEPDNEFIAQVSVISRLKHEHFVDLLGYCLEGDQRLLAYEFAT 623 E T VA+K ++ +A EF+ + SV+ H V LLG +G L+ E T Sbjct: 1024 DEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMT 1083 Query: 624 MGSLHDIL 647 G L L Sbjct: 1084 RGDLKSYL 1091
>KYK2_DICDI (P18161) Tyrosine-protein kinase 2 (EC 2.7.10.2) (Fragment)| Length = 410 Score = 47.4 bits (111), Expect = 4e-05 Identities = 37/125 (29%), Positives = 60/125 (48%), Gaps = 10/125 (8%) Frame = +3 Query: 306 IGDQGKAPPSIQVPELSFDELKE---------KTDDFGSKALVGEGSYGRVYYAVLENGT 458 + D +A S ++ + F+ELK +D VGEG++ V+ + G Sbjct: 72 LNDIQRAIESEKIKKTKFEELKSILGEREYIIDINDIQFIQKVGEGAFSEVWEGWWK-GI 130 Query: 459 HVAVKKLDTSADPEPDNE-FIAQVSVISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSL 635 HVA+KKL D E E FI +V + + H++ V +G C + + E+ GSL Sbjct: 131 HVAIKKLKIIGDEEQFKERFIREVQNLKKGNHQNIVMFIGACYK--PACIITEYMAGGSL 188 Query: 636 HDILH 650 ++ILH Sbjct: 189 YNILH 193
>TIE1_MOUSE (Q06806) Tyrosine-protein kinase receptor Tie-1 precursor (EC| 2.7.10.1) Length = 1134 Score = 47.4 bits (111), Expect = 4e-05 Identities = 32/110 (29%), Positives = 56/110 (50%), Gaps = 4/110 (3%) Frame = +3 Query: 330 PSIQVPELSFDELKEKTDDFGSKALVGEGSYGRVYYAVLENG---THVAVKKLDTSADPE 500 P Q LS+ L+ +D + L+GEG++G+V A+++ + A+K L A Sbjct: 818 PKPQPEPLSYPVLE--WEDITFEDLIGEGNFGQVIRAMIKKDGLKMNAAIKMLKEYASEN 875 Query: 501 PDNEFIAQVSVISRLKHE-HFVDLLGYCLEGDQRLLAYEFATMGSLHDIL 647 +F ++ V+ +L H + ++LLG C +A E+A G+L D L Sbjct: 876 DHRDFAGELEVLCKLGHHPNIINLLGACENRGYLYIAIEYAPYGNLLDFL 925
>FER_HUMAN (P16591) Proto-oncogene tyrosine-protein kinase FER (EC 2.7.10.2)| (p94-FER) (c-FER) Length = 822 Score = 47.4 bits (111), Expect = 4e-05 Identities = 34/142 (23%), Positives = 61/142 (42%) Frame = +3 Query: 204 RRWFCCAHVDTPYEENGDEFPHSPERANGNGFTQIGDQGKAPPSIQVPELSFDELKEKTD 383 RR F +VD Y G F + P+ + + T+ K+ + P + + Sbjct: 502 RRHFIIQYVDNMYRFEGTGFSNIPQLIDHHYTTKQVITKKSGVVLLNPIPKDKKWILSHE 561 Query: 384 DFGSKALVGEGSYGRVYYAVLENGTHVAVKKLDTSADPEPDNEFIAQVSVISRLKHEHFV 563 D L+G+G++G VY L++ T VAVK E +F+ + ++ + H + V Sbjct: 562 DVILGELLGKGNFGEVYKGTLKDKTSVAVKTCKEDLPQELKIKFLQEAKILKQYDHPNIV 621 Query: 564 DLLGYCLEGDQRLLAYEFATMG 629 L+G C + + E + G Sbjct: 622 KLIGVCTQRQPVYIIMELVSGG 643
>IGF1R_MOUSE (Q60751) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] Length = 1373 Score = 47.4 bits (111), Expect = 4e-05 Identities = 36/128 (28%), Positives = 55/128 (42%), Gaps = 8/128 (6%) Frame = +3 Query: 288 GNG--FTQIGDQGKAPPSIQVPELSFDELKEKTDDFGSKALVGEGSYGRVYYAVL----- 446 GNG + + + + + VP DE + + +G+GS+G VY V Sbjct: 969 GNGVLYASVNPEYFSAADVYVP----DEWEVAREKITMNRELGQGSFGMVYEGVAKGVVK 1024 Query: 447 -ENGTHVAVKKLDTSADPEPDNEFIAQVSVISRLKHEHFVDLLGYCLEGDQRLLAYEFAT 623 E T VA+K ++ +A EF+ + SV+ H V LLG +G L+ E T Sbjct: 1025 DEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMT 1084 Query: 624 MGSLHDIL 647 G L L Sbjct: 1085 RGDLKSYL 1092
>MUSK_HUMAN (O15146) Muscle, skeletal receptor tyrosine protein kinase| precursor (EC 2.7.10.1) (Muscle-specific tyrosine protein kinase receptor) (Muscle-specific kinase receptor) (MuSK) Length = 869 Score = 47.0 bits (110), Expect = 5e-05 Identities = 27/87 (31%), Positives = 44/87 (50%), Gaps = 6/87 (6%) Frame = +3 Query: 405 VGEGSYGRVYYA------VLENGTHVAVKKLDTSADPEPDNEFIAQVSVISRLKHEHFVD 566 +GEG++GRV+ A E T VAVK L A + +F + ++++ + + V Sbjct: 581 IGEGAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVK 640 Query: 567 LLGYCLEGDQRLLAYEFATMGSLHDIL 647 LLG C G L +E+ G L++ L Sbjct: 641 LLGVCAVGKPMCLLFEYMAYGDLNEFL 667
>DDR1_RAT (Q63474) Epithelial discoidin domain-containing receptor 1| precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (Protein- Length = 910 Score = 47.0 bits (110), Expect = 5e-05 Identities = 35/130 (26%), Positives = 54/130 (41%), Gaps = 17/130 (13%) Frame = +3 Query: 309 GDQGKAPPSIQVPELSFDELKEKTDDFGSKALVGEGSYGRVYYAVLENGTH--------- 461 G G PP + P KEK +GEG +G V+ +E+ Sbjct: 591 GAVGDGPPRVDFPRSRL-RFKEK---------LGEGQFGEVHLCEVEDPQDLVTSDFPIS 640 Query: 462 --------VAVKKLDTSADPEPDNEFIAQVSVISRLKHEHFVDLLGYCLEGDQRLLAYEF 617 VAVK L A N+F+ +V ++SRLK + + LLG C++ D + ++ Sbjct: 641 VQKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDLNIIRLLGVCVQDDPLCMITDY 700 Query: 618 ATMGSLHDIL 647 G L+ L Sbjct: 701 MENGDLNQFL 710
>FRK_HUMAN (P42685) Tyrosine-protein kinase FRK (EC 2.7.10.2) (Nuclear| tyrosine protein kinase RAK) Length = 505 Score = 47.0 bits (110), Expect = 5e-05 Identities = 37/117 (31%), Positives = 54/117 (46%), Gaps = 7/117 (5%) Frame = +3 Query: 318 GKAPPSIQVP---ELSFDELKEKTDDFGSKALV---GEGSYGRVYYAVLENGTHVAVKKL 479 GK IQVP +LS+ + + D S L+ G G +G V+ + N T VAVK L Sbjct: 205 GKPCLKIQVPAPFDLSYKTVDQWEIDRNSIQLLKRLGSGQFGEVWEGLWNNTTPVAVKTL 264 Query: 480 DT-SADPEPDNEFIAQVSVISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDIL 647 S DP N+F+ + ++ L+H + L C D + E GSL + L Sbjct: 265 KPGSMDP---NDFLREAQIMKNLRHPKLIQLYAVCTLEDPIYIITELMRHGSLQEYL 318
>MUSK_RAT (Q62838) Muscle, skeletal receptor tyrosine protein kinase| precursor (EC 2.7.10.1) (Muscle-specific kinase receptor) (MuSK) Length = 868 Score = 47.0 bits (110), Expect = 5e-05 Identities = 27/87 (31%), Positives = 44/87 (50%), Gaps = 6/87 (6%) Frame = +3 Query: 405 VGEGSYGRVYYA------VLENGTHVAVKKLDTSADPEPDNEFIAQVSVISRLKHEHFVD 566 +GEG++GRV+ A E T VAVK L A + +F + ++++ + + V Sbjct: 580 IGEGAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVK 639 Query: 567 LLGYCLEGDQRLLAYEFATMGSLHDIL 647 LLG C G L +E+ G L++ L Sbjct: 640 LLGVCAVGKPMCLLFEYMAYGDLNEFL 666
>MUSK_MOUSE (Q61006) Muscle, skeletal receptor tyrosine protein kinase| precursor (EC 2.7.10.1) (Muscle-specific kinase receptor) (MuSK) Length = 868 Score = 47.0 bits (110), Expect = 5e-05 Identities = 27/87 (31%), Positives = 44/87 (50%), Gaps = 6/87 (6%) Frame = +3 Query: 405 VGEGSYGRVYYA------VLENGTHVAVKKLDTSADPEPDNEFIAQVSVISRLKHEHFVD 566 +GEG++GRV+ A E T VAVK L A + +F + ++++ + + V Sbjct: 580 IGEGAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVK 639 Query: 567 LLGYCLEGDQRLLAYEFATMGSLHDIL 647 LLG C G L +E+ G L++ L Sbjct: 640 LLGVCAVGKPMCLLFEYMAYGDLNEFL 666
>M3K9_HUMAN (P80192) Mitogen-activated protein kinase kinase kinase 9 (EC| 2.7.11.25) (Mixed lineage kinase 1) Length = 1104 Score = 47.0 bits (110), Expect = 5e-05 Identities = 38/118 (32%), Positives = 55/118 (46%), Gaps = 3/118 (2%) Frame = +3 Query: 309 GDQGKAPPSIQVPELSFDELKEKTDDFGSKALVGEGSYGRVYYAVLENGTHVAVK--KLD 482 G+ P IQ+ E+ F EL + ++G G +G+VY A G VAVK + D Sbjct: 125 GEDPSCYPPIQLLEIDFAELT-------LEEIIGIGGFGKVYRAFWI-GDEVAVKAARHD 176 Query: 483 TSADPEPDNEFIAQ-VSVISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDILHG 653 D E + Q + + LKH + + L G CL+ L EFA G L+ +L G Sbjct: 177 PDEDISQTIENVRQEAKLFAMLKHPNIIALRGVCLKEPNLCLVMEFARGGPLNRVLSG 234
>TRK1_LYMST (O76997) Putative neurotrophin receptor LTRK 1 precursor (EC| 2.7.10.1) Length = 794 Score = 47.0 bits (110), Expect = 5e-05 Identities = 27/92 (29%), Positives = 45/92 (48%), Gaps = 8/92 (8%) Frame = +3 Query: 402 LVGEGSYGRVYYAVLENGTH------VAVKKLDTSADPEPDNEFIAQVSVISRLKHEHFV 563 ++GEG++GRV+ + VAVK L S +F + +++ ++H + V Sbjct: 509 VIGEGAFGRVFLGTCAHLIQKNEFAIVAVKTLKGSCSDSLKRDFEREAEMLATIEHANIV 568 Query: 564 DLLGYCLEGDQRLLAYEFATMGSLHDIL--HG 653 G C E DQ ++ +EF G L+ L HG Sbjct: 569 TFYGVCTESDQWMMIFEFMENGDLNKYLRMHG 600
>NTRK1_HUMAN (P04629) High affinity nerve growth factor receptor precursor (EC| 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1 transforming tyrosine kinase protein) (p140-TrkA) (Trk-A) Length = 796 Score = 46.6 bits (109), Expect = 6e-05 Identities = 31/101 (30%), Positives = 50/101 (49%), Gaps = 8/101 (7%) Frame = +3 Query: 375 KTDDFGSKALVGEGSYGRVYYAVLEN------GTHVAVKKLDTSADPEPDNEFIAQVSVI 536 K D K +GEG++G+V+ A N VAVK L +++ +F + ++ Sbjct: 506 KRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASE-SARQDFQREAELL 564 Query: 537 SRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDIL--HG 653 + L+H+H V G C EG L+ +E+ G L+ L HG Sbjct: 565 TMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHG 605
>NTRK1_CHICK (Q91009) High affinity nerve growth factor receptor precursor (EC| 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (Trk-A) (Fragment) Length = 778 Score = 46.6 bits (109), Expect = 6e-05 Identities = 29/91 (31%), Positives = 47/91 (51%), Gaps = 8/91 (8%) Frame = +3 Query: 405 VGEGSYGRVYYAVL------ENGTHVAVKKLDTSADPEPDNEFIAQVSVISRLKHEHFVD 566 +GEG++G+V+ A + T VAVK L + +F + +++ L+HEH V Sbjct: 499 LGEGAFGKVFLAECSHLLPEQEKTLVAVKALKEVTE-NARLDFQREAELLTVLQHEHIVK 557 Query: 567 LLGYCLEGDQRLLAYEFATMGSLHDIL--HG 653 G C EGD ++ +E+ G L+ L HG Sbjct: 558 FYGVCTEGDPLIMVFEYMKHGDLNRFLRSHG 588
>MUSK_CHICK (Q8AXY6) Muscle, skeletal receptor tyrosine protein kinase| precursor (EC 2.7.10.1) (Muscle-specific tyrosine protein kinase receptor) (Muscle-specific kinase receptor) (MuSK) Length = 947 Score = 46.6 bits (109), Expect = 6e-05 Identities = 27/87 (31%), Positives = 44/87 (50%), Gaps = 6/87 (6%) Frame = +3 Query: 405 VGEGSYGRVYYA------VLENGTHVAVKKLDTSADPEPDNEFIAQVSVISRLKHEHFVD 566 +GEG++GRV+ A E T VAVK L A + +F + ++++ + + V Sbjct: 661 IGEGAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVK 720 Query: 567 LLGYCLEGDQRLLAYEFATMGSLHDIL 647 LLG C G L +E+ G L++ L Sbjct: 721 LLGVCAVGKPMCLLFEYMAYGDLNEYL 747
>NTRK3_CHICK (Q91044) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (Trk-C) Length = 827 Score = 46.6 bits (109), Expect = 6e-05 Identities = 33/103 (32%), Positives = 51/103 (49%), Gaps = 10/103 (9%) Frame = +3 Query: 375 KTDDFGSKALVGEGSYGRVYYAVLENGTH------VAVKKLDTSADPE--PDNEFIAQVS 530 K D K +GEG++G+V+ A N + VAVK L DP +F + Sbjct: 536 KRRDIVLKRELGEGAFGKVFLAECYNLSPTNDKMLVAVKALK---DPTLAARKDFQREAE 592 Query: 531 VISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDIL--HG 653 +++ L+HEH V G C +GD ++ +E+ G L+ L HG Sbjct: 593 LLTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHG 635
>DDR1_HUMAN (Q08345) Epithelial discoidin domain-containing receptor 1| precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (TRK E) Length = 913 Score = 46.6 bits (109), Expect = 6e-05 Identities = 34/130 (26%), Positives = 54/130 (41%), Gaps = 17/130 (13%) Frame = +3 Query: 309 GDQGKAPPSIQVPELSFDELKEKTDDFGSKALVGEGSYGRVYYAVLENGTH--------- 461 G G PP + P KEK +GEG +G V+ +++ Sbjct: 594 GAVGDGPPRVDFPRSRL-RFKEK---------LGEGQFGEVHLCEVDSPQDLVSLDFPLN 643 Query: 462 --------VAVKKLDTSADPEPDNEFIAQVSVISRLKHEHFVDLLGYCLEGDQRLLAYEF 617 VAVK L A N+F+ +V ++SRLK + + LLG C++ D + ++ Sbjct: 644 VRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDY 703 Query: 618 ATMGSLHDIL 647 G L+ L Sbjct: 704 MENGDLNQFL 713
>NTRK3_RAT (Q03351) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (GP145-TrkC) (Trk-C) Length = 864 Score = 46.6 bits (109), Expect = 6e-05 Identities = 33/103 (32%), Positives = 51/103 (49%), Gaps = 10/103 (9%) Frame = +3 Query: 375 KTDDFGSKALVGEGSYGRVYYAVLENGTH------VAVKKLDTSADPE--PDNEFIAQVS 530 K D K +GEG++G+V+ A N + VAVK L DP +F + Sbjct: 534 KRRDIVLKRELGEGAFGKVFLAECYNLSPTKDKMLVAVKALK---DPTLAARKDFQREAE 590 Query: 531 VISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDIL--HG 653 +++ L+HEH V G C +GD ++ +E+ G L+ L HG Sbjct: 591 LLTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHG 633
>NTRK3_HUMAN (Q16288) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (GP145-TrkC) (Trk-C) Length = 839 Score = 46.6 bits (109), Expect = 6e-05 Identities = 33/103 (32%), Positives = 51/103 (49%), Gaps = 10/103 (9%) Frame = +3 Query: 375 KTDDFGSKALVGEGSYGRVYYAVLENGTH------VAVKKLDTSADPE--PDNEFIAQVS 530 K D K +GEG++G+V+ A N + VAVK L DP +F + Sbjct: 534 KRRDIVLKRELGEGAFGKVFLAECYNLSPTKDKMLVAVKALK---DPTLAARKDFQREAE 590 Query: 531 VISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDIL--HG 653 +++ L+HEH V G C +GD ++ +E+ G L+ L HG Sbjct: 591 LLTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHG 633
>FLK_RAT (P09760) Tyrosine-protein kinase FLK (EC 2.7.10.2) (Fragment)| Length = 323 Score = 46.6 bits (109), Expect = 6e-05 Identities = 35/148 (23%), Positives = 60/148 (40%) Frame = +3 Query: 204 RRWFCCAHVDTPYEENGDEFPHSPERANGNGFTQIGDQGKAPPSIQVPELSFDELKEKTD 383 RR F VD Y G F + P+ + + T+ K+ + P + + Sbjct: 3 RRHFIIQFVDNLYRFEGTGFSNIPQLIDHHFNTKQVITKKSGVVLLNPIPKDKKWVLNHE 62 Query: 384 DFGSKALVGEGSYGRVYYAVLENGTHVAVKKLDTSADPEPDNEFIAQVSVISRLKHEHFV 563 D L+G+G++G VY L++ T VAVK E +F+ + ++ + H + V Sbjct: 63 DVSLGELLGKGNFGEVYKGTLKDKTPVAVKTCKEDLPQELKIKFLQEAKILKQYDHPNIV 122 Query: 564 DLLGYCLEGDQRLLAYEFATMGSLHDIL 647 L+G C + + E G L Sbjct: 123 KLIGVCTQRQPVYIIMELVPGGDFLSFL 150
>NTRK3_SAIBB (Q5IS82) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) Length = 825 Score = 46.6 bits (109), Expect = 6e-05 Identities = 33/103 (32%), Positives = 51/103 (49%), Gaps = 10/103 (9%) Frame = +3 Query: 375 KTDDFGSKALVGEGSYGRVYYAVLENGTH------VAVKKLDTSADPE--PDNEFIAQVS 530 K D K +GEG++G+V+ A N + VAVK L DP +F + Sbjct: 534 KRRDIVLKRELGEGAFGKVFLAECYNLSPTKDKMLVAVKALK---DPTLAARKDFQREAE 590 Query: 531 VISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDIL--HG 653 +++ L+HEH V G C +GD ++ +E+ G L+ L HG Sbjct: 591 LLTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHG 633
>NTRK3_PANTR (Q5IS37) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) Length = 825 Score = 46.6 bits (109), Expect = 6e-05 Identities = 33/103 (32%), Positives = 51/103 (49%), Gaps = 10/103 (9%) Frame = +3 Query: 375 KTDDFGSKALVGEGSYGRVYYAVLENGTH------VAVKKLDTSADPE--PDNEFIAQVS 530 K D K +GEG++G+V+ A N + VAVK L DP +F + Sbjct: 534 KRRDIVLKRELGEGAFGKVFLAECYNLSPTKDKMLVAVKALK---DPTLAARKDFQREAE 590 Query: 531 VISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDIL--HG 653 +++ L+HEH V G C +GD ++ +E+ G L+ L HG Sbjct: 591 LLTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHG 633
>NTRK3_MACFA (Q5IFJ9) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) Length = 825 Score = 46.6 bits (109), Expect = 6e-05 Identities = 33/103 (32%), Positives = 51/103 (49%), Gaps = 10/103 (9%) Frame = +3 Query: 375 KTDDFGSKALVGEGSYGRVYYAVLENGTH------VAVKKLDTSADPE--PDNEFIAQVS 530 K D K +GEG++G+V+ A N + VAVK L DP +F + Sbjct: 534 KRRDIVLKRELGEGAFGKVFLAECYNLSPTKDKMLVAVKALK---DPTLAARKDFQREAE 590 Query: 531 VISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDIL--HG 653 +++ L+HEH V G C +GD ++ +E+ G L+ L HG Sbjct: 591 LLTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHG 633
>DDR1_PANTR (Q7YR43) Epithelial discoidin domain-containing receptor 1| precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (CD167a antigen) Length = 909 Score = 46.6 bits (109), Expect = 6e-05 Identities = 34/130 (26%), Positives = 54/130 (41%), Gaps = 17/130 (13%) Frame = +3 Query: 309 GDQGKAPPSIQVPELSFDELKEKTDDFGSKALVGEGSYGRVYYAVLENGTH--------- 461 G G PP + P KEK +GEG +G V+ +++ Sbjct: 590 GAVGDGPPRVDFPRSRL-RFKEK---------LGEGQFGEVHLCEVDSPQDLVSLDFPLN 639 Query: 462 --------VAVKKLDTSADPEPDNEFIAQVSVISRLKHEHFVDLLGYCLEGDQRLLAYEF 617 VAVK L A N+F+ +V ++SRLK + + LLG C++ D + ++ Sbjct: 640 VRKGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDY 699 Query: 618 ATMGSLHDIL 647 G L+ L Sbjct: 700 MENGDLNQFL 709
>TIE1_BOVIN (Q06805) Tyrosine-protein kinase receptor Tie-1 precursor (EC| 2.7.10.1) Length = 1136 Score = 46.2 bits (108), Expect = 8e-05 Identities = 27/93 (29%), Positives = 49/93 (52%), Gaps = 4/93 (4%) Frame = +3 Query: 381 DDFGSKALVGEGSYGRVYYAVLENG---THVAVKKLDTSADPEPDNEFIAQVSVISRLKH 551 +D + L+GEG++G+V A+++ + A+K L A +F ++ V+ +L H Sbjct: 835 EDITFEDLIGEGNFGQVIRAMIKKDGLKMNAAIKMLKEYASENDHRDFAGELEVLCKLGH 894 Query: 552 E-HFVDLLGYCLEGDQRLLAYEFATMGSLHDIL 647 + ++LLG C +A E+A G+L D L Sbjct: 895 HPNIINLLGACENRGYLYIAIEYAPYGNLLDFL 927
>STK_HYDAT (P17713) Tyrosine-protein kinase STK (EC 2.7.10.2) (P57-STK)| Length = 509 Score = 46.2 bits (108), Expect = 8e-05 Identities = 26/81 (32%), Positives = 40/81 (49%) Frame = +3 Query: 405 VGEGSYGRVYYAVLENGTHVAVKKLDTSADPEPDNEFIAQVSVISRLKHEHFVDLLGYCL 584 +G G +G V+ V N T VAVK L F+ + V+ +L+H+H V L C Sbjct: 246 LGAGQFGEVWAGVWNNTTQVAVKTLKPGTMSPAS--FLDEAGVMKKLRHKHLVQLYAICS 303 Query: 585 EGDQRLLAYEFATMGSLHDIL 647 + + + E+ + GSL D L Sbjct: 304 DREPIYIVTEYMSGGSLLDYL 324
>INSRR_MOUSE (Q9WTL4) Insulin receptor-related protein precursor (EC 2.7.10.1)| (IRR) (IR-related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain] Length = 1300 Score = 46.2 bits (108), Expect = 8e-05 Identities = 34/125 (27%), Positives = 54/125 (43%), Gaps = 6/125 (4%) Frame = +3 Query: 279 RANGNGFTQIGDQGKAPPSIQVPELSFDELKEKTDDFGSKALVGEGSYGRVYYAVL---- 446 + N +T + + + + VP DE + + +G+GS+G VY + Sbjct: 947 KRNSTLYTSVNPEYFSASHMYVP----DEWEVPREQIAIIRELGQGSFGMVYEGLARGLE 1002 Query: 447 --ENGTHVAVKKLDTSADPEPDNEFIAQVSVISRLKHEHFVDLLGYCLEGDQRLLAYEFA 620 E T VA+K ++ A EF+ + SV+ K H V LLG +G L+ E Sbjct: 1003 AGEESTPVALKTVNELASARERVEFLKEASVMKAFKCHHVVRLLGVVSQGQPTLVIMELM 1062 Query: 621 TMGSL 635 T G L Sbjct: 1063 TRGDL 1067
>STK3_HUMAN (Q13188) Serine/threonine-protein kinase 3 (EC 2.7.11.1)| (STE20-like kinase MST2) (MST-2) (Mammalian STE20-like protein kinase 2) (Serine/threonine-protein kinase Krs-1) Length = 491 Score = 46.2 bits (108), Expect = 8e-05 Identities = 33/114 (28%), Positives = 61/114 (53%), Gaps = 2/114 (1%) Frame = +3 Query: 312 DQGKAPPSIQVPELSFDELKEKTDD-FGSKALVGEGSYGRVYYAV-LENGTHVAVKKLDT 485 +Q AP S ++ +LS D L ++ ++ F +GEGSYG V+ A+ E+G VA+K++ Sbjct: 2 EQPPAPKS-KLKKLSEDSLTKQPEEVFDVLEKLGEGSYGSVFKAIHKESGQVVAIKQVPV 60 Query: 486 SADPEPDNEFIAQVSVISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDIL 647 +D + E I ++S++ + + V G + + E+ GS+ DI+ Sbjct: 61 ESDLQ---EIIKEISIMQQCDSPYVVKYYGSYFKNTDLWIVMEYCGAGSVSDII 111
>M3KL4_HUMAN (Q5TCX8) Mitogen-activated protein kinase kinase kinase (EC| 2.7.11.25) (Mixed lineage kinase 4) Length = 1036 Score = 46.2 bits (108), Expect = 8e-05 Identities = 31/89 (34%), Positives = 45/89 (50%), Gaps = 5/89 (5%) Frame = +3 Query: 396 KALVGEGSYGRVYYAVLENGTHVAVKKLDTSADPEPDNEFIAQ-----VSVISRLKHEHF 560 K L+G G +G+VY A + G VAVK DPE D A+ + + L+H + Sbjct: 127 KELIGAGGFGQVYRATWQ-GQEVAVKA--ARQDPEQDAAAAAESVRREARLFAMLRHPNI 183 Query: 561 VDLLGYCLEGDQRLLAYEFATMGSLHDIL 647 ++L G CL+ L EFA G+L+ L Sbjct: 184 IELRGVCLQQPHLCLVLEFARGGALNRAL 212
>PAK3_MOUSE (Q61036) Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1)| (p21-activated kinase 3) (PAK-3) (Beta-PAK) (CDC42/RAC effector kinase PAK-B) Length = 559 Score = 45.8 bits (107), Expect = 1e-04 Identities = 37/149 (24%), Positives = 70/149 (46%), Gaps = 9/149 (6%) Frame = +3 Query: 228 VDTPYEENGDEFPHSPERANGNGFTQIGDQGKAPPSIQVPEL--------SFDELKEKTD 383 + +P N ++ P S E AN + D+ + + E+ S + K+K Sbjct: 225 IASPAAPNKEDIPPSAENANSTTLYRNTDRQRKKSKMTDEEILEKLRSIVSVGDPKKKYT 284 Query: 384 DFGSKALVGEGSYGRVYYAV-LENGTHVAVKKLDTSADPEPDNEFIAQVSVISRLKHEHF 560 F +G+G+ G VY A+ + G VA+K+++ P+ + I ++ V+ K+ + Sbjct: 285 RFEK---IGQGASGTVYTALDIATGQEVAIKQMNLQQQPKKEL-IINEILVMRENKNPNI 340 Query: 561 VDLLGYCLEGDQRLLAYEFATMGSLHDIL 647 V+ L L GD+ + E+ GSL D++ Sbjct: 341 VNYLDSYLVGDELWVVMEYLAGGSLTDVV 369
>TMKL1_ARATH (P33543) Putative kinase-like protein TMKL1 precursor| Length = 674 Score = 45.8 bits (107), Expect = 1e-04 Identities = 37/136 (27%), Positives = 62/136 (45%), Gaps = 1/136 (0%) Frame = +3 Query: 246 ENGDEFPHSPERANGNGFTQIGDQGKAPPSIQVPELSFDELKEKTDDFGSKALVGEGSYG 425 E GDE E+ G G + G+ L+ D++ T K SYG Sbjct: 339 EEGDEEDEIGEKEGGEGKLVVFQGGE--------NLTLDDVLNATGQVMEKT-----SYG 385 Query: 426 RVYYAVLENGTHVAVKKLDTSADPEPDNEFIAQVSVISRLKHEHFVDLLG-YCLEGDQRL 602 VY A L +G ++A++ L + + + + + R++HE+ V L Y + ++L Sbjct: 386 TVYKAKLSDGGNIALRLLREGTCKDRSS-CLPVIRQLGRIRHENLVPLRAFYQGKRGEKL 444 Query: 603 LAYEFATMGSLHDILH 650 L Y++ SLHD+LH Sbjct: 445 LIYDYLPNISLHDLLH 460
>TIE2_BRARE (O73791) Tyrosine-protein kinase receptor Tie-2 precursor (EC| 2.7.10.1) Length = 1116 Score = 45.8 bits (107), Expect = 1e-04 Identities = 30/92 (32%), Positives = 51/92 (55%), Gaps = 4/92 (4%) Frame = +3 Query: 384 DFGSKALVGEGSYGRVYYA-VLENGTHV--AVKKLDTSADPEPDNEFIAQVSVISRL-KH 551 D + ++GEG++G+V A + ++G + AVK++ A + +F ++ V+ RL H Sbjct: 815 DIQFQDVLGEGNFGQVLKARIRKDGLRMDAAVKRMKDYASQDDHRDFAGELEVLCRLGPH 874 Query: 552 EHFVDLLGYCLEGDQRLLAYEFATMGSLHDIL 647 ++ + LLG C LA EFA G+L D L Sbjct: 875 KNIIHLLGACEHRGYLYLAIEFAPHGNLLDFL 906
>INSR_DROME (P09208) Insulin-like receptor precursor (EC 2.7.10.1) (DIR) (DInr)| (dIRH) [Contains: Insulin-like receptor alpha subunit; Insulin-like receptor beta 1 subunit; Insulin-like receptor beta 2 subunit] Length = 2144 Score = 45.4 bits (106), Expect = 1e-04 Identities = 28/89 (31%), Positives = 42/89 (47%), Gaps = 6/89 (6%) Frame = +3 Query: 399 ALVGEGSYGRVYYAVLE----NGT--HVAVKKLDTSADPEPDNEFIAQVSVISRLKHEHF 560 A +G+GS+G VY +L+ NG A+K ++ +A F+++ SV+ H Sbjct: 1375 APLGQGSFGMVYEGILKSFPPNGVDRECAIKTVNENATDRERTNFLSEASVMKEFDTYHV 1434 Query: 561 VDLLGYCLEGDQRLLAYEFATMGSLHDIL 647 V LLG C G L+ E G L L Sbjct: 1435 VRLLGVCSRGQPALVVMELMKKGDLKSYL 1463
>IGF1R_XENLA (O73798) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (xIGF-1R) (xIGFR) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] Length = 1358 Score = 45.4 bits (106), Expect = 1e-04 Identities = 28/87 (32%), Positives = 41/87 (47%), Gaps = 6/87 (6%) Frame = +3 Query: 405 VGEGSYGRVYYAVL------ENGTHVAVKKLDTSADPEPDNEFIAQVSVISRLKHEHFVD 566 +G+GS+G VY + E T VA+K ++ +A EF+ + SV+ H V Sbjct: 1001 LGQGSFGMVYEGIAKGVVKDEAETKVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVR 1060 Query: 567 LLGYCLEGDQRLLAYEFATMGSLHDIL 647 LLG +G L+ E T G L L Sbjct: 1061 LLGVVSQGQPTLVIMELMTRGDLKSYL 1087
>IRAK3_MOUSE (Q8K4B2) Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1)| (IRAK-3) (IL-1 receptor-associated kinase M) (IRAK-M) Length = 609 Score = 45.4 bits (106), Expect = 1e-04 Identities = 29/108 (26%), Positives = 50/108 (46%), Gaps = 3/108 (2%) Frame = +3 Query: 333 SIQVPELSFDELKEKTDDFGSKALVGEGSYGRVYYAVLENGTHVAVKKLDTSADPEPD-- 506 ++Q +SF + E T F L+GEG VY + N + AVK + Sbjct: 160 TLQKTPISFQSILEGTKHFHKDFLIGEGEIFEVYRVDIRNQAY-AVKLFKQEKKMQLKKH 218 Query: 507 -NEFIAQVSVISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDIL 647 F++++ V+ +H H ++L Y E ++ L Y + + G+L D L Sbjct: 219 WKRFLSELEVLLLFRHPHILELAAYFTETEKLCLVYPYMSNGTLFDRL 266
>CDKL2_RAT (Q5XIT0) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| Length = 507 Score = 45.1 bits (105), Expect = 2e-04 Identities = 31/93 (33%), Positives = 51/93 (54%), Gaps = 2/93 (2%) Frame = +3 Query: 372 EKTDDFGSKALVGEGSYGRVYYAV-LENGTHVAVKK-LDTSADPEPDNEFIAQVSVISRL 545 EK ++ G LVGEGSYG V ++G VA+KK L++ D + ++ ++ +L Sbjct: 2 EKYENLG---LVGEGSYGMVMKCRNKDSGRIVAIKKFLESDDDKMVKKIAMREIKLLKQL 58 Query: 546 KHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDI 644 +HE+ V+LL C + + L +EF L D+ Sbjct: 59 RHENLVNLLEVCKKKKRWYLVFEFVDHTILDDL 91
>CDKL2_MOUSE (Q9QUK0) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| (Serine/threonine-protein kinase KKIAMRE) Length = 568 Score = 45.1 bits (105), Expect = 2e-04 Identities = 31/93 (33%), Positives = 51/93 (54%), Gaps = 2/93 (2%) Frame = +3 Query: 372 EKTDDFGSKALVGEGSYGRVYYAV-LENGTHVAVKK-LDTSADPEPDNEFIAQVSVISRL 545 EK ++ G LVGEGSYG V ++G VA+KK L++ D + ++ ++ +L Sbjct: 2 EKYENLG---LVGEGSYGMVMKCRNKDSGRIVAIKKFLESDDDKMVKKIAMREIKLLKQL 58 Query: 546 KHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDI 644 +HE+ V+LL C + + L +EF L D+ Sbjct: 59 RHENLVNLLEVCKKKKRWYLVFEFVDHTILDDL 91
>RIPK1_MOUSE (Q60855) Receptor-interacting serine/threonine-protein kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein) Length = 656 Score = 45.1 bits (105), Expect = 2e-04 Identities = 28/102 (27%), Positives = 48/102 (47%), Gaps = 1/102 (0%) Frame = +3 Query: 345 PELSFDELKEKTDDFGSKALVGEGSYGRVYYAVLENGTHVAVKKLDTSADPEPDNEFIAQ 524 P++S D +K + D K + G +G+V + V +KK+ T + NE + + Sbjct: 3 PDMSLDNIKMASSDLLEKTDLDSGGFGKVSLCYHRSHGFVILKKVYTGPNRAEYNEVLLE 62 Query: 525 VS-VISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDIL 647 ++ RL+H V LLG +E L E+ G+L +L Sbjct: 63 EGKMMHRLRHSRVVKLLGIIIEEGNYSLVMEYMEKGNLMHVL 104
>CDKL2_RABIT (Q9TTK0) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| (Serine/threonine-protein kinase KKIAMRE) Length = 566 Score = 45.1 bits (105), Expect = 2e-04 Identities = 31/93 (33%), Positives = 51/93 (54%), Gaps = 2/93 (2%) Frame = +3 Query: 372 EKTDDFGSKALVGEGSYGRVYYAV-LENGTHVAVKK-LDTSADPEPDNEFIAQVSVISRL 545 EK ++ G LVGEGSYG V ++G VA+KK L++ D + ++ ++ +L Sbjct: 2 EKYENLG---LVGEGSYGMVMKCRNKDSGRIVAIKKFLESDDDKMVKKIAMREIKLLKQL 58 Query: 546 KHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDI 644 +HE+ V+LL C + + L +EF L D+ Sbjct: 59 RHENLVNLLEVCKKKKRWYLVFEFVDHTILDDL 91
>ABL2_HUMAN (P42684) Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine| leukemia viral oncogene homolog 2) (Tyrosine kinase ARG) Length = 1182 Score = 45.1 bits (105), Expect = 2e-04 Identities = 31/97 (31%), Positives = 45/97 (46%), Gaps = 1/97 (1%) Frame = +3 Query: 360 DELKEKTDDFGSKALVGEGSYGRVYYAVLEN-GTHVAVKKLDTSADPEPDNEFIAQVSVI 536 D+ + + D K +G G YG VY V + VAVK L D EF+ + +V+ Sbjct: 279 DKWEMERTDITMKHKLGGGQYGEVYVGVWKKYSLTVAVKTL--KEDTMEVEEFLKEAAVM 336 Query: 537 SRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDIL 647 +KH + V LLG C + E+ G+L D L Sbjct: 337 KEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYL 373
>CDKL2_PONPY (Q5R754) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| Length = 493 Score = 44.7 bits (104), Expect = 2e-04 Identities = 31/93 (33%), Positives = 50/93 (53%), Gaps = 2/93 (2%) Frame = +3 Query: 372 EKTDDFGSKALVGEGSYGRVYYAV-LENGTHVAVKK-LDTSADPEPDNEFIAQVSVISRL 545 EK ++ G LVGEGSYG V + G VA+KK L++ D + ++ ++ +L Sbjct: 2 EKYENLG---LVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQL 58 Query: 546 KHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDI 644 +HE+ V+LL C + + L +EF L D+ Sbjct: 59 RHENLVNLLEVCKKKKRWYLVFEFVDHTILDDL 91
>CDKL2_HUMAN (Q92772) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| (Serine/threonine-protein kinase KKIAMRE) (Protein kinase p56 KKIAMRE) Length = 493 Score = 44.7 bits (104), Expect = 2e-04 Identities = 31/93 (33%), Positives = 50/93 (53%), Gaps = 2/93 (2%) Frame = +3 Query: 372 EKTDDFGSKALVGEGSYGRVYYAV-LENGTHVAVKK-LDTSADPEPDNEFIAQVSVISRL 545 EK ++ G LVGEGSYG V + G VA+KK L++ D + ++ ++ +L Sbjct: 2 EKYENLG---LVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQL 58 Query: 546 KHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDI 644 +HE+ V+LL C + + L +EF L D+ Sbjct: 59 RHENLVNLLEVCKKKKRWYLVFEFVDHTILDDL 91
>LIMK1_DROME (Q8IR79) LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1) (dLIMK)| Length = 1257 Score = 44.7 bits (104), Expect = 2e-04 Identities = 23/82 (28%), Positives = 39/82 (47%) Frame = +3 Query: 405 VGEGSYGRVYYAVLENGTHVAVKKLDTSADPEPDNEFIAQVSVISRLKHEHFVDLLGYCL 584 +GEG +G+V+ V V K AD E FI +V+V+ L H H + +G Sbjct: 407 LGEGFFGKVFKVTHRQSGEVMVLKELHRADEEAQRNFIKEVAVLRLLDHRHVLKFIGVLY 466 Query: 585 EGDQRLLAYEFATMGSLHDILH 650 + + + E+ G L +++H Sbjct: 467 KDKKLHMVTEYVAGGCLKELIH 488
>CDC2_DROME (P23572) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) Length = 297 Score = 44.7 bits (104), Expect = 2e-04 Identities = 29/84 (34%), Positives = 46/84 (54%), Gaps = 2/84 (2%) Frame = +3 Query: 381 DDFGSKALVGEGSYGRVYYAVLE-NGTHVAVKKLDTSADPEP-DNEFIAQVSVISRLKHE 554 +DF +GEG+YG VY G VA+KK+ +D E + I ++S++ LKHE Sbjct: 2 EDFEKIEKIGEGTYGVVYKGRNRLTGQIVAMKKIRLESDDEGVPSTAIREISLLKELKHE 61 Query: 555 HFVDLLGYCLEGDQRLLAYEFATM 626 + V L +E ++ L +EF +M Sbjct: 62 NIVCLEDVLMEENRIYLIFEFLSM 85
>CDKL2_MACFA (Q4R7T5) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| Length = 570 Score = 44.7 bits (104), Expect = 2e-04 Identities = 31/93 (33%), Positives = 50/93 (53%), Gaps = 2/93 (2%) Frame = +3 Query: 372 EKTDDFGSKALVGEGSYGRVYYAV-LENGTHVAVKK-LDTSADPEPDNEFIAQVSVISRL 545 EK ++ G LVGEGSYG V + G VA+KK L++ D + ++ ++ +L Sbjct: 2 EKYENLG---LVGEGSYGMVVKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQL 58 Query: 546 KHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDI 644 +HE+ V+LL C + + L +EF L D+ Sbjct: 59 RHENLVNLLEVCKKKKRWYLVFEFVDHTILDDL 91
>ZYG1_CAEBR (Q621J7) Probable serine/threonine-protein kinase zyg-1 (EC| 2.7.11.1) (Zygote defective protein 1) Length = 709 Score = 44.7 bits (104), Expect = 2e-04 Identities = 27/89 (30%), Positives = 40/89 (44%) Frame = +3 Query: 375 KTDDFGSKALVGEGSYGRVYYAVLENGTHVAVKKLDTSADPEPDNEFIAQVSVISRLKHE 554 K F + +G+G +G VY A ENG VA+KK+ +A E ++ + L+H Sbjct: 9 KLSSFQNLQQIGQGGFGVVYSAQRENGEKVAIKKIGNAASQTRIKE---EIKTMKLLRHR 65 Query: 555 HFVDLLGYCLEGDQRLLAYEFATMGSLHD 641 + V E + L E GSL D Sbjct: 66 NIVQFYETFFENGETYLVMELCEGGSLMD 94
>JAK2_HUMAN (O60674) Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase| 2) (JAK-2) Length = 1132 Score = 44.7 bits (104), Expect = 2e-04 Identities = 29/101 (28%), Positives = 47/101 (46%), Gaps = 8/101 (7%) Frame = +3 Query: 369 KEKTDDFGSKALVGEGSYGRVYYAVLE--------NGTHVAVKKLDTSADPEPDNEFIAQ 524 K + +D +G+G++ +++ V + T V +K LD A F Sbjct: 539 KIRNEDLIFNESLGQGTFTKIFKGVRREVGDYGQLHETEVLLKVLD-KAHRNYSESFFEA 597 Query: 525 VSVISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDIL 647 S++S+L H+H V G C+ GD+ +L EF GSL L Sbjct: 598 ASMMSKLSHKHLVLNYGVCVCGDENILVQEFVKFGSLDTYL 638 Score = 40.4 bits (93), Expect = 0.005 Identities = 36/120 (30%), Positives = 58/120 (48%), Gaps = 14/120 (11%) Frame = +3 Query: 330 PSIQVPELSFDELKEKTD--DFGSKAL-----VGEGSYGRV----YYAVLEN-GTHVAVK 473 P++++ L F E D F + L +G+G++G V Y + +N G VAVK Sbjct: 823 PNMRIGALGFSGAFEDRDPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVK 882 Query: 474 KLDTSADPEPDNEFIAQVSVISRLKHEHFVDLLGYCLEGDQR--LLAYEFATMGSLHDIL 647 KL S + E +F ++ ++ L+H++ V G C +R L E+ GSL D L Sbjct: 883 KLQHSTE-EHLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLKLIMEYLPYGSLRDYL 941
>TIE2_HUMAN (Q02763) Angiopoietin-1 receptor precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen) Length = 1124 Score = 44.3 bits (103), Expect = 3e-04 Identities = 27/93 (29%), Positives = 52/93 (55%), Gaps = 4/93 (4%) Frame = +3 Query: 381 DDFGSKALVGEGSYGRVYYA-VLENGTHV--AVKKLDTSADPEPDNEFIAQVSVISRLKH 551 +D + ++GEG++G+V A + ++G + A+K++ A + +F ++ V+ +L H Sbjct: 822 NDIKFQDVIGEGNFGQVLKARIKKDGLRMDAAIKRMKEYASKDDHRDFAGELEVLCKLGH 881 Query: 552 E-HFVDLLGYCLEGDQRLLAYEFATMGSLHDIL 647 + ++LLG C LA E+A G+L D L Sbjct: 882 HPNIINLLGACEHRGYLYLAIEYAPHGNLLDFL 914
>INSR_AEDAE (Q93105) Insulin-like receptor precursor (EC 2.7.10.1) (MIR)| [Contains: Insulin-like receptor alpha chain; Insulin-like receptor beta chain] Length = 1390 Score = 44.3 bits (103), Expect = 3e-04 Identities = 26/87 (29%), Positives = 40/87 (45%), Gaps = 6/87 (6%) Frame = +3 Query: 405 VGEGSYGRVYYAVLEN------GTHVAVKKLDTSADPEPDNEFIAQVSVISRLKHEHFVD 566 +G+GS+G VY +L A+K ++ SA + F+ + SV+ + H V Sbjct: 1031 LGQGSFGMVYKGILTQLRGEKCNQPCAIKTVNESATAREKDSFLLEASVMKQFNTHHVVR 1090 Query: 567 LLGYCLEGDQRLLAYEFATMGSLHDIL 647 LLG +GD L+ E G L L Sbjct: 1091 LLGVVSQGDPTLVIMELMANGDLKSYL 1117
>PAK3_RAT (Q62829) Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1)| (p21-activated kinase 3) (PAK-3) (Beta-PAK) (p65-PAK) Length = 544 Score = 44.3 bits (103), Expect = 3e-04 Identities = 37/149 (24%), Positives = 70/149 (46%), Gaps = 9/149 (6%) Frame = +3 Query: 228 VDTPYEENGDEFPHSPERANGNGFTQIGDQGKAPPSIQVPEL--------SFDELKEKTD 383 + +P N + P S E AN + + D+ + + E+ S + K+K Sbjct: 210 IASPAAPNKEATPPSAENANSSTLYRNTDRQRKKSKMTDEEILEKLRSIVSVGDPKKKYT 269 Query: 384 DFGSKALVGEGSYGRVYYAV-LENGTHVAVKKLDTSADPEPDNEFIAQVSVISRLKHEHF 560 F +G+G+ G VY A+ + G VA+K+++ P+ + I ++ V+ K+ + Sbjct: 270 RFEK---IGQGASGTVYTALDIATGQEVAIKQMNLQQQPKKEL-IINEILVMRENKNPNI 325 Query: 561 VDLLGYCLEGDQRLLAYEFATMGSLHDIL 647 V+ L L GD+ + E+ GSL D++ Sbjct: 326 VNYLDSYLVGDELWVVMEYLAGGSLTDVV 354
>CDC2C_DROME (P23573) Cell division control protein 2 cognate (EC 2.7.11.22) (EC| 2.7.11.23) Length = 314 Score = 44.3 bits (103), Expect = 3e-04 Identities = 26/84 (30%), Positives = 44/84 (52%), Gaps = 2/84 (2%) Frame = +3 Query: 381 DDFGSKALVGEGSYGRVYYAVLEN-GTHVAVKKLDTSADPE-PDNEFIAQVSVISRLKHE 554 D+F +GEG+YG VY A + G VA+KK+ + E + I ++S++ LKH Sbjct: 6 DNFQRAEKIGEGTYGIVYKARSNSTGQDVALKKIRLEGETEGVPSTAIREISLLKNLKHP 65 Query: 555 HFVDLLGYCLEGDQRLLAYEFATM 626 + V L + G+ + +E+ M Sbjct: 66 NVVQLFDVVISGNNLYMIFEYLNM 89
>TIE2_MOUSE (Q02858) Angiopoietin-1 receptor precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen) Length = 1122 Score = 44.3 bits (103), Expect = 3e-04 Identities = 27/93 (29%), Positives = 52/93 (55%), Gaps = 4/93 (4%) Frame = +3 Query: 381 DDFGSKALVGEGSYGRVYYA-VLENGTHV--AVKKLDTSADPEPDNEFIAQVSVISRLKH 551 +D + ++GEG++G+V A + ++G + A+K++ A + +F ++ V+ +L H Sbjct: 820 NDIKFQDVIGEGNFGQVLKARIKKDGLRMDAAIKRMKEYASKDDHRDFAGELEVLCKLGH 879 Query: 552 E-HFVDLLGYCLEGDQRLLAYEFATMGSLHDIL 647 + ++LLG C LA E+A G+L D L Sbjct: 880 HPNIINLLGACEHRGYLYLAIEYAPHGNLLDFL 912
>TIE2_BOVIN (Q06807) Angiopoietin-1 receptor precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor TIE-2) (CD202b antigen) Length = 1125 Score = 44.3 bits (103), Expect = 3e-04 Identities = 27/93 (29%), Positives = 52/93 (55%), Gaps = 4/93 (4%) Frame = +3 Query: 381 DDFGSKALVGEGSYGRVYYA-VLENGTHV--AVKKLDTSADPEPDNEFIAQVSVISRLKH 551 +D + ++GEG++G+V A + ++G + A+K++ A + +F ++ V+ +L H Sbjct: 823 NDIKFQDVIGEGNFGQVLKARIKKDGLRMDAAIKRMKEYASKDDHRDFAGELEVLCKLGH 882 Query: 552 E-HFVDLLGYCLEGDQRLLAYEFATMGSLHDIL 647 + ++LLG C LA E+A G+L D L Sbjct: 883 HPNIINLLGACEHRGYLYLAIEYAPHGNLLDFL 915
>TAOK2_XENLA (Q6GPK9) Serine/threonine-protein kinase TAO2 (EC 2.7.11.1)| (Thousand and one amino acid protein 2) Length = 1025 Score = 43.9 bits (102), Expect = 4e-04 Identities = 33/106 (31%), Positives = 52/106 (49%), Gaps = 3/106 (2%) Frame = +3 Query: 339 QVPELSFDELKEKTDDFGSKALVGEGSYGRVYYA-VLENGTHVAVKKLDTSA--DPEPDN 509 +V EL F + EK F +G GS+G VY+A + N VA+KK+ S E Sbjct: 14 EVAELFFKDDPEKL--FADLREIGHGSFGAVYFARDIRNNEVVAIKKMSYSGKQSNEKWQ 71 Query: 510 EFIAQVSVISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDIL 647 + I +V + +L+H + ++ G L L E+ +GS D+L Sbjct: 72 DIIKEVKFLQKLRHPNTIEYKGCYLREHTAWLVMEYC-LGSASDLL 116
>ILPR_BRALA (O02466) Insulin-like peptide receptor precursor (EC 2.7.10.1) (ILP| receptor) [Contains: Insulin-like peptide receptor alpha chain; Insulin-like peptide receptor beta chain] Length = 1363 Score = 43.9 bits (102), Expect = 4e-04 Identities = 40/157 (25%), Positives = 60/157 (38%), Gaps = 6/157 (3%) Frame = +3 Query: 195 VIMRRWFCCAHVDTPYEENGDEFPHSPERANGNGFTQIGDQGKAPPSIQVPELSFDELKE 374 VI W+C T + P+ A+ N D P +VP ++E Sbjct: 945 VIFGIWYC-----TKKRFGDKQMPNGVLYASVNPEYMSSDDVYVPDEWEVPREKITLIRE 999 Query: 375 KTDDFGSKALVGEGSYGRVYYAVL------ENGTHVAVKKLDTSADPEPDNEFIAQVSVI 536 +G+GS+G VY E VAVK ++ SA EF+ + SV+ Sbjct: 1000 ----------LGQGSFGMVYEGEAKDVVKDEPMVSVAVKTVNESASIRERIEFLNEASVM 1049 Query: 537 SRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDIL 647 H V L+G +G L+ E +G L + L Sbjct: 1050 KTFNCHHVVKLMGVVSKGQPTLVVMELMALGDLKNYL 1086
>LTK_HUMAN (P29376) Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1)| (Protein tyrosine kinase 1) Length = 864 Score = 43.9 bits (102), Expect = 4e-04 Identities = 22/87 (25%), Positives = 43/87 (49%), Gaps = 6/87 (6%) Frame = +3 Query: 405 VGEGSYGRVYYAVL------ENGTHVAVKKLDTSADPEPDNEFIAQVSVISRLKHEHFVD 566 +G G++G VY ++ + VA+K L P+ + +F+ + +IS+ +H++ V Sbjct: 516 LGHGAFGEVYEGLVIGLPGDSSPLQVAIKTLPELCSPQDELDFLMEALIISKFRHQNIVR 575 Query: 567 LLGYCLEGDQRLLAYEFATMGSLHDIL 647 +G L RL+ E + G + L Sbjct: 576 CVGLSLRATPRLILLELMSGGDMKSFL 602
>ROR2_DROME (Q9V6K3) Tyrosine-protein kinase transmembrane receptor Ror2| precursor (EC 2.7.10.1) (Neurospecific receptor tyrosine kinase) Length = 724 Score = 43.9 bits (102), Expect = 4e-04 Identities = 28/107 (26%), Positives = 47/107 (43%), Gaps = 6/107 (5%) Frame = +3 Query: 345 PELSFDELKEKTDDFGSKALVGEGSYGRVYYAVL------ENGTHVAVKKLDTSADPEPD 506 P ++L+ D +G+G++GRV+ A + VAVK L A + Sbjct: 427 PNARLEKLEYPRGDIVYVRSLGQGAFGRVFQARAPGLVPDQEDLLVAVKMLKDDASDQMQ 486 Query: 507 NEFIAQVSVISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDIL 647 +F + +++ H + V LLG C G L +E+ G L + L Sbjct: 487 MDFEREACLLAEFDHPNIVRLLGVCALGRPMCLLFEYMAPGDLSEFL 533
>STK3_MOUSE (Q9JI10) Serine/threonine-protein kinase 3 (EC 2.7.11.1)| (STE20-like kinase MST2) (MST-2) (Mammalian STE20-like protein kinase 2) Length = 497 Score = 43.9 bits (102), Expect = 4e-04 Identities = 29/105 (27%), Positives = 56/105 (53%), Gaps = 2/105 (1%) Frame = +3 Query: 339 QVPELSFDELKEKTDD-FGSKALVGEGSYGRVYYAV-LENGTHVAVKKLDTSADPEPDNE 512 ++ +LS D L ++ ++ F +GEGSYG V+ A+ E+G VA+K++ +D + E Sbjct: 10 KLKKLSEDSLTKQPEEVFDVLEKLGEGSYGSVFKAIHKESGQVVAIKQVPVESDLQ---E 66 Query: 513 FIAQVSVISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDIL 647 I ++S++ + + V G + + E+ GS+ DI+ Sbjct: 67 IIKEISIMQQCDSPYVVKYYGSYFKNTDLWIVMEYCGAGSVSDII 111
>PAK3_PONPY (Q7YQL3) Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1)| (p21-activated kinase 3) (PAK-3) Length = 559 Score = 43.5 bits (101), Expect = 5e-04 Identities = 37/149 (24%), Positives = 70/149 (46%), Gaps = 9/149 (6%) Frame = +3 Query: 228 VDTPYEENGDEFPHSPERANGNGFTQIGDQGKAPPSIQVPEL--------SFDELKEKTD 383 + +P N + P S E AN + + D+ + + E+ S + K+K Sbjct: 225 IASPAVPNKEVTPPSAENANSSTLYRNTDRQRKKSKMTDEEILEKLRSIVSVGDPKKKYT 284 Query: 384 DFGSKALVGEGSYGRVYYAV-LENGTHVAVKKLDTSADPEPDNEFIAQVSVISRLKHEHF 560 F +G+G+ G VY A+ + G VA+K+++ P+ + I ++ V+ K+ + Sbjct: 285 RFEK---IGQGASGTVYTALDIATGQEVAIKQMNLQQQPKKEL-IINEILVMRENKNPNI 340 Query: 561 VDLLGYCLEGDQRLLAYEFATMGSLHDIL 647 V+ L L GD+ + E+ GSL D++ Sbjct: 341 VNYLDSYLVGDELWVVMEYLAGGSLTDVV 369
>PAK3_PANTR (Q7YQL4) Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1)| (p21-activated kinase 3) (PAK-3) Length = 559 Score = 43.5 bits (101), Expect = 5e-04 Identities = 37/149 (24%), Positives = 70/149 (46%), Gaps = 9/149 (6%) Frame = +3 Query: 228 VDTPYEENGDEFPHSPERANGNGFTQIGDQGKAPPSIQVPEL--------SFDELKEKTD 383 + +P N + P S E AN + + D+ + + E+ S + K+K Sbjct: 225 IASPAVPNKEVTPPSAENANSSTLYRNTDRQRKKSKMTDEEILEKLRSIVSVGDPKKKYT 284 Query: 384 DFGSKALVGEGSYGRVYYAV-LENGTHVAVKKLDTSADPEPDNEFIAQVSVISRLKHEHF 560 F +G+G+ G VY A+ + G VA+K+++ P+ + I ++ V+ K+ + Sbjct: 285 RFEK---IGQGASGTVYTALDIATGQEVAIKQMNLQQQPKKEL-IINEILVMRENKNPNI 340 Query: 561 VDLLGYCLEGDQRLLAYEFATMGSLHDIL 647 V+ L L GD+ + E+ GSL D++ Sbjct: 341 VNYLDSYLVGDELWVVMEYLAGGSLTDVV 369
>PAK3_HUMAN (O75914) Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1)| (p21-activated kinase 3) (PAK-3) (Beta-PAK) (Oligophrenin-3) Length = 559 Score = 43.5 bits (101), Expect = 5e-04 Identities = 37/149 (24%), Positives = 70/149 (46%), Gaps = 9/149 (6%) Frame = +3 Query: 228 VDTPYEENGDEFPHSPERANGNGFTQIGDQGKAPPSIQVPEL--------SFDELKEKTD 383 + +P N + P S E AN + + D+ + + E+ S + K+K Sbjct: 225 IASPAVPNKEVTPPSAENANSSTLYRNTDRQRKKSKMTDEEILEKLRSIVSVGDPKKKYT 284 Query: 384 DFGSKALVGEGSYGRVYYAV-LENGTHVAVKKLDTSADPEPDNEFIAQVSVISRLKHEHF 560 F +G+G+ G VY A+ + G VA+K+++ P+ + I ++ V+ K+ + Sbjct: 285 RFEK---IGQGASGTVYTALDIATGQEVAIKQMNLQQQPKKEL-IINEILVMRENKNPNI 340 Query: 561 VDLLGYCLEGDQRLLAYEFATMGSLHDIL 647 V+ L L GD+ + E+ GSL D++ Sbjct: 341 VNYLDSYLVGDELWVVMEYLAGGSLTDVV 369
>ERBB4_HUMAN (Q15303) Receptor tyrosine-protein kinase erbB-4 precursor (EC| 2.7.10.1) (p180erbB4) (Tyrosine kinase-type cell surface receptor HER4) Length = 1308 Score = 43.5 bits (101), Expect = 5e-04 Identities = 34/116 (29%), Positives = 56/116 (48%), Gaps = 5/116 (4%) Frame = +3 Query: 318 GKAPPSIQVPELSFDELKEKTDDFGSKALVGEGSYGRVYYAVL--ENGT---HVAVKKLD 482 G AP Q+ L ELK ++G G++G VY + E T VA+K L+ Sbjct: 702 GTAPNQAQLRILKETELKRVK-------VLGSGAFGTVYKGIWVPEGETVKIPVAIKILN 754 Query: 483 TSADPEPDNEFIAQVSVISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDILH 650 + P+ + EF+ + +++ + H H V LLG CL +L+ + G L + +H Sbjct: 755 ETTGPKANVEFMDEALIMASMDHPHLVRLLGVCLSPTIQLVT-QLMPHGCLLEYVH 809
>CSF1R_MOUSE (P09581) Macrophage colony-stimulating factor 1 receptor precursor| (CSF-1-R) (EC 2.7.10.1) (Fms proto-oncogene) (c-fms) Length = 977 Score = 43.5 bits (101), Expect = 5e-04 Identities = 37/131 (28%), Positives = 59/131 (45%), Gaps = 7/131 (5%) Frame = +3 Query: 276 ERANGNGFTQIGDQGKAPPSIQVPELSFDELKEKTDDFGSKALVGEGSYGRVYYAVL--- 446 ER GN +T I Q+P E FG +G G++G+V A Sbjct: 552 ERYEGNSYTFIDPT-------QLPYNEKWEFPRNNLQFGKT--LGAGAFGKVVEATAFGL 602 Query: 447 ---ENGTHVAVKKLDTSADPEPDNEFIAQVSVISRL-KHEHFVDLLGYCLEGDQRLLAYE 614 + VAVK L ++A + ++++ ++S L +HE+ V+LLG C G L+ E Sbjct: 603 GKEDAVLKVAVKMLKSTAHADEKEALMSELKIMSHLGQHENIVNLLGACTHGGPVLVITE 662 Query: 615 FATMGSLHDIL 647 + G L + L Sbjct: 663 YCCYGDLLNFL 673
>CSF1R_RAT (Q00495) Macrophage colony-stimulating factor 1 receptor precursor| (CSF-1-R) (EC 2.7.10.1) (Fms proto-oncogene) (c-fms) Length = 978 Score = 43.5 bits (101), Expect = 5e-04 Identities = 37/131 (28%), Positives = 59/131 (45%), Gaps = 7/131 (5%) Frame = +3 Query: 276 ERANGNGFTQIGDQGKAPPSIQVPELSFDELKEKTDDFGSKALVGEGSYGRVYYAVL--- 446 ER GN +T I Q+P E FG +G G++G+V A Sbjct: 552 ERYEGNSYTFIDPT-------QLPYNEKWEFPRNNLQFGKT--LGAGAFGKVVEATAFGL 602 Query: 447 ---ENGTHVAVKKLDTSADPEPDNEFIAQVSVISRL-KHEHFVDLLGYCLEGDQRLLAYE 614 + VAVK L ++A + ++++ ++S L +HE+ V+LLG C G L+ E Sbjct: 603 GKEDAVLKVAVKMLKSTAHADEKEALMSELKIMSHLGQHENIVNLLGACTHGGPVLVITE 662 Query: 615 FATMGSLHDIL 647 + G L + L Sbjct: 663 YCCYGDLLNFL 673
>XMRK_XIPMA (P13388) Melanoma receptor tyrosine-protein kinase precursor (EC| 2.7.10.1) Length = 1167 Score = 43.1 bits (100), Expect = 7e-04 Identities = 28/97 (28%), Positives = 51/97 (52%), Gaps = 5/97 (5%) Frame = +3 Query: 330 PSIQVPELSFDELKEKTDDFGSKALVGEGSYGRVYYAVLE-NGTH----VAVKKLDTSAD 494 PS Q P +F + ++T+ F ++G G++G VY + +G + VA+K L + Sbjct: 692 PSGQAPNQAFLRILKETE-FKKDRVLGSGAFGTVYKGLWNPDGENIRIPVAIKVLREATS 750 Query: 495 PEPDNEFIAQVSVISRLKHEHFVDLLGYCLEGDQRLL 605 P+ + E + + V++ + H H LLG CL +L+ Sbjct: 751 PKVNQEVLDEAYVMASVDHPHVCRLLGICLTSAVQLV 787
>TAOK1_RAT (O88664) Serine/threonine-protein kinase TAO1 (EC 2.7.11.1)| (Thousand and one amino acid protein 1) Length = 1001 Score = 43.1 bits (100), Expect = 7e-04 Identities = 33/106 (31%), Positives = 51/106 (48%), Gaps = 3/106 (2%) Frame = +3 Query: 339 QVPELSFDELKEKTDDFGSKALVGEGSYGRVYYA-VLENGTHVAVKKLDTSA--DPEPDN 509 ++ EL F E EK F +G GS+G VY+A + VA+KK+ S E Sbjct: 14 EIAELFFKEDPEKL--FTDLREIGHGSFGAVYFARDVRTNEVVAIKKMSYSGKQSTEKWQ 71 Query: 510 EFIAQVSVISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDIL 647 + I +V + R+KH + ++ G L L E+ +GS D+L Sbjct: 72 DIIKEVKFLQRIKHPNSIEYKGCYLREHTAWLVMEYC-LGSASDLL 116
>TAOK1_MOUSE (Q5F2E8) Serine/threonine-protein kinase TAO1 (EC 2.7.11.1)| (Thousand and one amino acid protein 1) Length = 1001 Score = 43.1 bits (100), Expect = 7e-04 Identities = 33/106 (31%), Positives = 51/106 (48%), Gaps = 3/106 (2%) Frame = +3 Query: 339 QVPELSFDELKEKTDDFGSKALVGEGSYGRVYYA-VLENGTHVAVKKLDTSA--DPEPDN 509 ++ EL F E EK F +G GS+G VY+A + VA+KK+ S E Sbjct: 14 EIAELFFKEDPEKL--FTDLREIGHGSFGAVYFARDVRTNEVVAIKKMSYSGKQSTEKWQ 71 Query: 510 EFIAQVSVISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDIL 647 + I +V + R+KH + ++ G L L E+ +GS D+L Sbjct: 72 DIIKEVKFLQRIKHPNSIEYKGCYLREHTAWLVMEYC-LGSASDLL 116
>TAOK1_HUMAN (Q7L7X3) Serine/threonine-protein kinase TAO1 (EC 2.7.11.1)| (Thousand and one amino acid protein 1) (STE20-like kinase PSK2) (Kinase from chicken homolog B) (hKFC-B) Length = 1001 Score = 43.1 bits (100), Expect = 7e-04 Identities = 33/106 (31%), Positives = 51/106 (48%), Gaps = 3/106 (2%) Frame = +3 Query: 339 QVPELSFDELKEKTDDFGSKALVGEGSYGRVYYA-VLENGTHVAVKKLDTSA--DPEPDN 509 ++ EL F E EK F +G GS+G VY+A + VA+KK+ S E Sbjct: 14 EIAELFFKEDPEKL--FTDLREIGHGSFGAVYFARDVRTNEVVAIKKMSYSGKQSTEKWQ 71 Query: 510 EFIAQVSVISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDIL 647 + I +V + R+KH + ++ G L L E+ +GS D+L Sbjct: 72 DIIKEVKFLQRIKHPNSIEYKGCYLREHTAWLVMEYC-LGSASDLL 116
>INSR_XENLA (Q9PVZ4) Insulin receptor precursor (EC 2.7.10.1) (IR) (Xe-InsR)| (XTK-1b) [Contains: Insulin receptor alpha subunit; Insulin receptor beta subunit] Length = 1362 Score = 43.1 bits (100), Expect = 7e-04 Identities = 31/102 (30%), Positives = 43/102 (42%), Gaps = 6/102 (5%) Frame = +3 Query: 360 DELKEKTDDFGSKALVGEGSYGRVYYAVL------ENGTHVAVKKLDTSADPEPDNEFIA 521 DE + D +G+GS+G VY + E VAVK ++ SA EF+ Sbjct: 1003 DEWEVPRDKINLLRELGQGSFGMVYEGIAKDIIKGEPEVRVAVKTVNESASLRERIEFLN 1062 Query: 522 QVSVISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDIL 647 + SV+ H V LLG +G L+ E G L L Sbjct: 1063 EASVMKAFNCHHVVRLLGVVSKGQPTLVIMELMAHGDLKSYL 1104
>ERBB4_RAT (Q62956) Receptor tyrosine-protein kinase erbB-4 precursor (EC| 2.7.10.1) Length = 1308 Score = 43.1 bits (100), Expect = 7e-04 Identities = 34/116 (29%), Positives = 56/116 (48%), Gaps = 5/116 (4%) Frame = +3 Query: 318 GKAPPSIQVPELSFDELKEKTDDFGSKALVGEGSYGRVYYAVL--ENGT---HVAVKKLD 482 G AP Q+ L ELK ++G G++G VY + E T VA+K L+ Sbjct: 702 GTAPNQAQLRILKETELKRVK-------VLGSGAFGTVYKGIWVPEGETVKIPVAIKILN 754 Query: 483 TSADPEPDNEFIAQVSVISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDILH 650 + P+ + EF+ + +++ + H H V LLG CL +L+ + G L + +H Sbjct: 755 ETTGPKANVEFMDEALIMASVDHPHLVRLLGVCLSPTIQLVT-QLMPHGCLLEYVH 809
>HTK16_HYDAT (P53356) Tyrosine-protein kinase HTK16 (EC 2.7.10.2)| Length = 757 Score = 42.7 bits (99), Expect = 0.001 Identities = 35/98 (35%), Positives = 49/98 (50%), Gaps = 4/98 (4%) Frame = +3 Query: 366 LKEKTDDFGSKALVGEGSYGRVYYAV-LENG---THVAVKKLDTSADPEPDNEFIAQVSV 533 LKE FG + +G G +G V + L G +VA+K L + + EF+ + V Sbjct: 480 LKESIS-FGKE--LGVGEFGSVIKGIWLSPGGKEINVAMKTLHKDKMVQGEKEFLREALV 536 Query: 534 ISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDIL 647 +S+L H V LLG CL G +L E MG+L D L Sbjct: 537 MSQLNHPCIVSLLGVCL-GPPMILVQELVEMGALLDYL 573
>TYK2_HUMAN (P29597) Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)| Length = 1187 Score = 42.7 bits (99), Expect = 0.001 Identities = 29/88 (32%), Positives = 46/88 (52%), Gaps = 7/88 (7%) Frame = +3 Query: 405 VGEGSYGRVY---YAVLENGTH--VAVKKLDTSADPEPDNEFIAQVSVISRLKHEHFVDL 569 +GEG +G+V Y +GT VAVK L P+ + + ++ ++ L HEH + Sbjct: 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 Query: 570 LGYCL-EGDQRL-LAYEFATMGSLHDIL 647 G C +G++ L L E+ +GSL D L Sbjct: 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL 990
>JAK2_MOUSE (Q62120) Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase| 2) (JAK-2) Length = 1129 Score = 42.7 bits (99), Expect = 0.001 Identities = 28/101 (27%), Positives = 47/101 (46%), Gaps = 8/101 (7%) Frame = +3 Query: 369 KEKTDDFGSKALVGEGSYGRVYYAVLE--------NGTHVAVKKLDTSADPEPDNEFIAQ 524 K + +D +G+G++ +++ V + T V +K LD A F Sbjct: 539 KIRNEDLIFNESLGQGTFTKIFKGVRREVGDYGQLHKTEVLLKVLD-KAHRNYSESFFEA 597 Query: 525 VSVISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDIL 647 S++S+L H+H V G C+ G++ +L EF GSL L Sbjct: 598 ASMMSQLSHKHLVLNYGVCVCGEENILVQEFVKFGSLDTYL 638 Score = 40.4 bits (93), Expect = 0.005 Identities = 36/120 (30%), Positives = 58/120 (48%), Gaps = 14/120 (11%) Frame = +3 Query: 330 PSIQVPELSFDELKEKTD--DFGSKAL-----VGEGSYGRV----YYAVLEN-GTHVAVK 473 P++++ L F E D F + L +G+G++G V Y + +N G VAVK Sbjct: 823 PNMRIGALGFSGAFEDRDPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVK 882 Query: 474 KLDTSADPEPDNEFIAQVSVISRLKHEHFVDLLGYCLEGDQR--LLAYEFATMGSLHDIL 647 KL S + E +F ++ ++ L+H++ V G C +R L E+ GSL D L Sbjct: 883 KLQHSTE-EHLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLRLIMEYLPYGSLRDYL 941
>INSR_HUMAN (P06213) Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220| antigen) [Contains: Insulin receptor alpha subunit; Insulin receptor beta subunit] Length = 1382 Score = 42.7 bits (99), Expect = 0.001 Identities = 35/113 (30%), Positives = 48/113 (42%), Gaps = 6/113 (5%) Frame = +3 Query: 327 PPSIQVPELSFDELKEKTDDFGSKALVGEGSYGRVYYAVL------ENGTHVAVKKLDTS 488 P S+ VP DE + + +G+GS+G VY E T VAVK ++ S Sbjct: 1007 PCSVYVP----DEWEVSREKITLLRELGQGSFGMVYEGNARDIIKGEAETRVAVKTVNES 1062 Query: 489 ADPEPDNEFIAQVSVISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDIL 647 A EF+ + SV+ H V LLG +G L+ E G L L Sbjct: 1063 ASLRERIEFLNEASVMKGFTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYL 1115
>CDC2_RANDY (Q9W739) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) Length = 302 Score = 42.7 bits (99), Expect = 0.001 Identities = 26/84 (30%), Positives = 46/84 (54%), Gaps = 2/84 (2%) Frame = +3 Query: 381 DDFGSKALVGEGSYGRVYYAVLE-NGTHVAVKKLDTSADPEP-DNEFIAQVSVISRLKHE 554 D++ +GEG+YG VY V + G VA+KK+ + E + I ++S++ L+H Sbjct: 2 DEYAKIEKIGEGTYGVVYKGVHKATGQIVAMKKIRLENEEEGVPSTAIREISLLKELQHP 61 Query: 555 HFVDLLGYCLEGDQRLLAYEFATM 626 + V LL ++ + L +EF +M Sbjct: 62 NIVCLLDVLMQDSRLYLIFEFLSM 85
>M3K3_ARATH (O22042) Mitogen-activated protein kinase kinase kinase 3 (EC| 2.7.11.25) (Arabidospsis NPK1-related protein kinase 3) Length = 651 Score = 42.7 bits (99), Expect = 0.001 Identities = 36/126 (28%), Positives = 59/126 (46%), Gaps = 10/126 (7%) Frame = +3 Query: 300 TQIGDQGKAPPSIQVPELSFDELKEKTDDFGSKA--LVGEGSYGRVYYAV-LENGTHVAV 470 ++IG K PP + P KE+ + L+G G++GRVY + L++G +A+ Sbjct: 43 SRIGLFSKPPPGLPAPR------KEEAPSIRWRKGELIGCGAFGRVYMGMNLDSGELLAI 96 Query: 471 KKL---DTSADPEPDN----EFIAQVSVISRLKHEHFVDLLGYCLEGDQRLLAYEFATMG 629 K++ +SA E E +V ++ L H + V LG E D + EF G Sbjct: 97 KQVLIAPSSASKEKTQGHIRELEEEVQLLKNLSHPNIVRYLGTVRESDSLNILMEFVPGG 156 Query: 630 SLHDIL 647 S+ +L Sbjct: 157 SISSLL 162
>KPEL_DROME (Q05652) Probable serine/threonine-protein kinase pelle (EC| 2.7.11.1) Length = 501 Score = 42.7 bits (99), Expect = 0.001 Identities = 34/151 (22%), Positives = 66/151 (43%), Gaps = 22/151 (14%) Frame = +3 Query: 249 NGDEFPHSPERANGNGFTQIGDQGKAPPSIQ----------------VPELSFDELKEKT 380 NG FP S +N N + PS++ + E+ + EL+ T Sbjct: 151 NGPPFPSSSGVSNSNNNRTSTTATEEIPSLESLGNIHISTVQRAAESLLEIDYAELENAT 210 Query: 381 DDFGSKALVGEGSYGRVYYAVLENGTHVAVKKLDTSADPEPDNEFIA------QVSVISR 542 D + +G+G +G VY + VA+K ++ + P D + + ++ ++ Sbjct: 211 DGWSPDNRLGQGGFGDVYRGKWKQ-LDVAIKVMNYRS-PNIDQKMVELQQSYNELKYLNS 268 Query: 543 LKHEHFVDLLGYCLEGDQRLLAYEFATMGSL 635 ++H++ + L GY ++G + L Y+ GSL Sbjct: 269 IRHDNILALYGYSIKGGKPCLVYQLMKGGSL 299
>CD2L5_MOUSE (Q69ZA1) Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22)| (CDC2-related protein kinase 5) Length = 1511 Score = 42.7 bits (99), Expect = 0.001 Identities = 36/122 (29%), Positives = 57/122 (46%), Gaps = 11/122 (9%) Frame = +3 Query: 237 PYEENGDEFPHSPERANGNGFTQIGDQGKAPPSIQVPELSFDELKEKTDDFGSKA----- 401 P GD+ SPE T K P I P + E+KEK D+G + Sbjct: 653 PELPGGDDLSKSPEEKK----TAAQLHSKRRPKICGPR--YGEIKEKDIDWGKRCVDKFD 706 Query: 402 ---LVGEGSYGRVYYA-VLENGTHVAVKK--LDTSADPEPDNEFIAQVSVISRLKHEHFV 563 ++GEG+YG+VY A + G VA+KK LD + P I ++ ++ +L H+ + Sbjct: 707 IIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITA-IREIKILRQLTHQSII 765 Query: 564 DL 569 ++ Sbjct: 766 NM 767
>ROR1_MOUSE (Q9Z139) Tyrosine-protein kinase transmembrane receptor ROR1| precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1) (mROR1) Length = 937 Score = 42.7 bits (99), Expect = 0.001 Identities = 24/86 (27%), Positives = 44/86 (51%), Gaps = 5/86 (5%) Frame = +3 Query: 405 VGEGSYGRVYYAVL-----ENGTHVAVKKLDTSADPEPDNEFIAQVSVISRLKHEHFVDL 569 +GE ++G++Y L ++ VA+K L +P+ EF + S+++ L H + V L Sbjct: 479 LGECTFGKIYKGHLYLPGMDHAQLVAIKTLKDYNNPQQWTEFQQEASLMAELHHPNIVCL 538 Query: 570 LGYCLEGDQRLLAYEFATMGSLHDIL 647 LG + + +E+ G LH+ L Sbjct: 539 LGAVTQEQPVCMLFEYMNQGDLHEFL 564
>SULU_CAEEL (P46549) Serine/threonine-protein kinase SULU (EC 2.7.11.1)| (Protein kinase 18) Length = 982 Score = 42.7 bits (99), Expect = 0.001 Identities = 32/104 (30%), Positives = 52/104 (50%), Gaps = 3/104 (2%) Frame = +3 Query: 345 PELSFDELKEKTDDFGSKALVGEGSYGRVYYAV-LENGTHVAVKKLDTSADP--EPDNEF 515 PE + +L+E +G GS+G VY+A +N VA+KK++ S E N+ Sbjct: 26 PEQRYQDLRE----------IGHGSFGAVYFAYDKKNEQTVAIKKMNFSGKQAVEKWNDI 75 Query: 516 IAQVSVISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDIL 647 + +VS ++ + H H VD L+ L E+ +GS DI+ Sbjct: 76 LKEVSFLNTVVHPHIVDYKACFLKDTTCWLVMEYC-IGSAADIV 118
>IRAK2_HUMAN (O43187) Interleukin-1 receptor-associated kinase-like 2 (IRAK-2)| Length = 590 Score = 42.7 bits (99), Expect = 0.001 Identities = 27/100 (27%), Positives = 45/100 (45%), Gaps = 3/100 (3%) Frame = +3 Query: 363 ELKEKTDDFGSKALVGEGSYGRVYYAVLENGTHVAVKKLDTSADPEP---DNEFIAQVSV 533 ++ + TDDF + +G++ VY +G KKL +A P + F A++ + Sbjct: 202 DVVQATDDFNQNRKISQGTFADVYRGH-RHGKPFVFKKLRETACSSPGSIERFFQAELQI 260 Query: 534 ISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDILHG 653 R H + + +LG+C Y + GSL D L G Sbjct: 261 CLRCCHPNVLPVLGFCAARQFHSFIYPYMANGSLQDRLQG 300
>JAK2_RAT (Q62689) Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase| 2) (JAK-2) Length = 1132 Score = 42.7 bits (99), Expect = 0.001 Identities = 28/101 (27%), Positives = 47/101 (46%), Gaps = 8/101 (7%) Frame = +3 Query: 369 KEKTDDFGSKALVGEGSYGRVYYAVLE--------NGTHVAVKKLDTSADPEPDNEFIAQ 524 K + +D +G+G++ +++ V + T V +K LD A F Sbjct: 539 KIRNEDLIFNESLGQGTFTKIFKGVRREVGDYGQLHETEVLLKVLD-KAHRNYSESFFEA 597 Query: 525 VSVISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDIL 647 S++S+L H+H V G C+ G++ +L EF GSL L Sbjct: 598 ASMMSQLSHKHLVLNYGVCVCGEENILVQEFVKFGSLDTYL 638 Score = 40.4 bits (93), Expect = 0.005 Identities = 36/120 (30%), Positives = 58/120 (48%), Gaps = 14/120 (11%) Frame = +3 Query: 330 PSIQVPELSFDELKEKTD--DFGSKAL-----VGEGSYGRV----YYAVLEN-GTHVAVK 473 P++++ L F E D F + L +G+G++G V Y + +N G VAVK Sbjct: 823 PNMRIGALGFSGAFEDRDPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVK 882 Query: 474 KLDTSADPEPDNEFIAQVSVISRLKHEHFVDLLGYCLEGDQR--LLAYEFATMGSLHDIL 647 KL S + E +F ++ ++ L+H++ V G C +R L E+ GSL D L Sbjct: 883 KLQHSTE-EHLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLRLIMEYLPYGSLRDYL 941
>TNI3K_RAT (Q7TQP6) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 834 Score = 42.4 bits (98), Expect = 0.001 Identities = 30/108 (27%), Positives = 52/108 (48%), Gaps = 3/108 (2%) Frame = +3 Query: 336 IQVPELSFDELKEKTDDFGSKALVGEGSYGRVYYAVLENGTHVAVKKL--DTSADPEPDN 509 +Q+ E+ F E+ +G GS+G+VY N VA+K+ +T + Sbjct: 457 LQLSEIEFHEI------------IGSGSFGKVYKGRCRNKI-VAIKRYRANTYCSKSDVD 503 Query: 510 EFIAQVSVISRLKHEHFVDLLGYCLEG-DQRLLAYEFATMGSLHDILH 650 F +VS++ +L H V +G CL+ Q + ++ + GSL +LH Sbjct: 504 MFCREVSILCQLNHPCVVQFVGACLDDPSQFAIVTQYISGGSLFSLLH 551
>INSR_MOUSE (P15208) Insulin receptor precursor (EC 2.7.10.1) (IR) [Contains:| Insulin receptor alpha subunit; Insulin receptor beta subunit] Length = 1372 Score = 42.4 bits (98), Expect = 0.001 Identities = 34/109 (31%), Positives = 47/109 (43%), Gaps = 6/109 (5%) Frame = +3 Query: 327 PPSIQVPELSFDELKEKTDDFGSKALVGEGSYGRVYYAVL------ENGTHVAVKKLDTS 488 P S+ VP DE + + +G+GS+G VY E T VAVK ++ S Sbjct: 997 PSSVYVP----DEWEVPREKITLLRELGQGSFGMVYEGNAKDIIKGEAETRVAVKTVNES 1052 Query: 489 ADPEPDNEFIAQVSVISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSL 635 A EF+ + SV+ H V LLG +G L+ E G L Sbjct: 1053 ASLRERIEFLNEASVMKGFTCHHVVRLLGVVSKGQPMLVVMELMAHGDL 1101
>KSYK_HUMAN (P43405) Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine| kinase) Length = 635 Score = 42.4 bits (98), Expect = 0.001 Identities = 28/85 (32%), Positives = 47/85 (55%), Gaps = 4/85 (4%) Frame = +3 Query: 405 VGEGSYGRV---YYAVLENGTHVAVKKLDTSA-DPEPDNEFIAQVSVISRLKHEHFVDLL 572 +G G++G V YY + + VAVK L A DP +E +A+ +V+ +L + + V ++ Sbjct: 377 LGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRMI 436 Query: 573 GYCLEGDQRLLAYEFATMGSLHDIL 647 G C E + +L E A +G L+ L Sbjct: 437 GIC-EAESWMLVMEMAELGPLNKYL 460
>PTK6_MOUSE (Q64434) Tyrosine-protein kinase 6 (EC 2.7.10.2) (SRC-related| intestinal kinase) Length = 451 Score = 42.4 bits (98), Expect = 0.001 Identities = 24/97 (24%), Positives = 47/97 (48%) Frame = +3 Query: 357 FDELKEKTDDFGSKALVGEGSYGRVYYAVLENGTHVAVKKLDTSADPEPDNEFIAQVSVI 536 +D+ + ++F +G G +G V+ A+ + HVAVK + + + F A++ + Sbjct: 181 WDDWERPREEFTLCKKLGAGYFGEVFEALWKGQVHVAVKVISRD-NLLHQHTFQAEIQAM 239 Query: 537 SRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDIL 647 +L+H+H + L GD + E G+L +L Sbjct: 240 KKLRHKHILSLYAVATAGDPVYIITELMPKGNLLQLL 276
>TNI3K_MOUSE (Q5GIG6) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 833 Score = 42.4 bits (98), Expect = 0.001 Identities = 30/108 (27%), Positives = 52/108 (48%), Gaps = 3/108 (2%) Frame = +3 Query: 336 IQVPELSFDELKEKTDDFGSKALVGEGSYGRVYYAVLENGTHVAVKKL--DTSADPEPDN 509 +Q+ E+ F E+ +G GS+G+VY N VA+K+ +T + Sbjct: 456 LQLSEIEFHEI------------IGSGSFGKVYKGRCRNKI-VAIKRYRANTYCSKSDVD 502 Query: 510 EFIAQVSVISRLKHEHFVDLLGYCLEG-DQRLLAYEFATMGSLHDILH 650 F +VS++ +L H V +G CL+ Q + ++ + GSL +LH Sbjct: 503 MFCREVSILCQLNHPCVVQFVGACLDDPSQFAIVTQYISGGSLFSLLH 550
>KSYK_MOUSE (P48025) Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine| kinase) Length = 629 Score = 42.4 bits (98), Expect = 0.001 Identities = 28/85 (32%), Positives = 47/85 (55%), Gaps = 4/85 (4%) Frame = +3 Query: 405 VGEGSYGRV---YYAVLENGTHVAVKKLDTSA-DPEPDNEFIAQVSVISRLKHEHFVDLL 572 +G G++G V YY + + VAVK L A DP +E +A+ +V+ +L + + V ++ Sbjct: 371 LGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRMI 430 Query: 573 GYCLEGDQRLLAYEFATMGSLHDIL 647 G C E + +L E A +G L+ L Sbjct: 431 GIC-EAESWMLVMEMAELGPLNKYL 454
>KSYK_PIG (Q00655) Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine| kinase) [Contains: 72 kDa tyrosine-protein kinase SYK; 40 kDa tyrosine-protein kinase SYK] Length = 628 Score = 42.4 bits (98), Expect = 0.001 Identities = 28/85 (32%), Positives = 47/85 (55%), Gaps = 4/85 (4%) Frame = +3 Query: 405 VGEGSYGRV---YYAVLENGTHVAVKKLDTSA-DPEPDNEFIAQVSVISRLKHEHFVDLL 572 +G G++G V YY + + VAVK L A DP +E +A+ +V+ +L + + V ++ Sbjct: 370 LGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRMI 429 Query: 573 GYCLEGDQRLLAYEFATMGSLHDIL 647 G C E + +L E A +G L+ L Sbjct: 430 GIC-EAESWMLVMEMAELGPLNKYL 453
>SRC2_XENLA (P13116) Tyrosine-protein kinase Src-2 (EC 2.7.10.2) (p60-Src-2)| Length = 531 Score = 42.0 bits (97), Expect = 0.002 Identities = 31/106 (29%), Positives = 48/106 (45%), Gaps = 1/106 (0%) Frame = +3 Query: 339 QVPELSFDELKEKTDDFGSKALVGEGSYGRVYYAVLENGTHVAVKKLDT-SADPEPDNEF 515 Q LS D + D + +G+G +G V+ T VA+K L + PE F Sbjct: 249 QTQGLSKDAWEIPRDSLRLELKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPE---AF 305 Query: 516 IAQVSVISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDILHG 653 + + V+ +L+HE V L E + + E+ + GSL D L G Sbjct: 306 LQEAQVMKKLRHEKLVQLYAVVSE-EPIYIVTEYMSKGSLLDFLKG 350
>SRC1_XENLA (P13115) Tyrosine-protein kinase Src-1 (EC 2.7.10.2) (p60-Src-1)| Length = 531 Score = 42.0 bits (97), Expect = 0.002 Identities = 31/106 (29%), Positives = 48/106 (45%), Gaps = 1/106 (0%) Frame = +3 Query: 339 QVPELSFDELKEKTDDFGSKALVGEGSYGRVYYAVLENGTHVAVKKLDT-SADPEPDNEF 515 Q LS D + D + +G+G +G V+ T VA+K L + PE F Sbjct: 249 QTQGLSRDAWEIPRDSLRLELKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPE---AF 305 Query: 516 IAQVSVISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDILHG 653 + + V+ +L+HE V L E + + E+ + GSL D L G Sbjct: 306 LQEAQVMKKLRHEKLVQLYAVVSE-EPIYIVTEYISKGSLLDFLKG 350
>CC2H1_TRYBB (P38973) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| Length = 301 Score = 42.0 bits (97), Expect = 0.002 Identities = 27/76 (35%), Positives = 41/76 (53%), Gaps = 2/76 (2%) Frame = +3 Query: 405 VGEGSYGRVYYA-VLENGTHVAVKKLDTSADPE-PDNEFIAQVSVISRLKHEHFVDLLGY 578 +GEGSYG V+ A + GT VAVK++ + E I ++S++ L+HE+ V LL Sbjct: 11 IGEGSYGVVFRARDVTTGTIVAVKRIRLEKEEEGVPCTAIREISILKELRHENIVRLLDV 70 Query: 579 CLEGDQRLLAYEFATM 626 C + L +E M Sbjct: 71 CHSEKRLTLVFECMEM 86
>RIPK1_HUMAN (Q13546) Receptor-interacting serine/threonine-protein kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein) Length = 671 Score = 42.0 bits (97), Expect = 0.002 Identities = 26/102 (25%), Positives = 49/102 (48%), Gaps = 1/102 (0%) Frame = +3 Query: 345 PELSFDELKEKTDDFGSKALVGEGSYGRVYYAVLENGTHVAVKKLDTSADPEPDNE-FIA 521 P++S + +K K+ DF A + G +G+V + +K + + NE + Sbjct: 3 PDMSLNVIKMKSSDFLESAELDSGGFGKVSLCFHRTQGLMIMKTVYKGPNCIEHNEALLE 62 Query: 522 QVSVISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDIL 647 + +++RL+H V LLG +E + L E+ G+L +L Sbjct: 63 EAKMMNRLRHSRVVKLLGVIIEEGKYSLVMEYMEKGNLMHVL 104
>SRK1_SPOLA (P42686) Tyrosine-protein kinase isoform SRK1 (EC 2.7.10.2)| Length = 505 Score = 42.0 bits (97), Expect = 0.002 Identities = 24/83 (28%), Positives = 38/83 (45%) Frame = +3 Query: 405 VGEGSYGRVYYAVLENGTHVAVKKLDTSADPEPDNEFIAQVSVISRLKHEHFVDLLGYCL 584 +G G +G V+ + T VAVK L EF+ + S++ RL+H + L C Sbjct: 246 LGAGQFGEVWEGLWNGTTSVAVKTLKPGTMSV--EEFLQEASIMKRLRHPKLIQLYAVCT 303 Query: 585 EGDQRLLAYEFATMGSLHDILHG 653 + + + E GSL + L G Sbjct: 304 KEEPIYIVTELMKYGSLLEYLRG 326
>INSR_RAT (P15127) Insulin receptor precursor (EC 2.7.10.1) (IR) [Contains:| Insulin receptor alpha subunit; Insulin receptor beta subunit] Length = 1383 Score = 42.0 bits (97), Expect = 0.002 Identities = 33/109 (30%), Positives = 48/109 (44%), Gaps = 6/109 (5%) Frame = +3 Query: 327 PPSIQVPELSFDELKEKTDDFGSKALVGEGSYGRVYYAVLEN------GTHVAVKKLDTS 488 P S+ VP DE + + +G+GS+G VY ++ T VAVK ++ S Sbjct: 1008 PSSVYVP----DEWEVPREKITLLRELGQGSFGMVYEGNAKDIIKGEVETRVAVKTVNES 1063 Query: 489 ADPEPDNEFIAQVSVISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSL 635 A EF+ + SV+ H V LLG +G L+ E G L Sbjct: 1064 ASLRERIEFLNEASVMKGFTCHHVVRLLGVVSKGQPTLVVMELMAHGDL 1112
>SRC64_DROME (P00528) Tyrosine-protein kinase Src64B (EC 2.7.10.2) (Dsrc64)| Length = 552 Score = 42.0 bits (97), Expect = 0.002 Identities = 22/81 (27%), Positives = 38/81 (46%) Frame = +3 Query: 405 VGEGSYGRVYYAVLENGTHVAVKKLDTSADPEPDNEFIAQVSVISRLKHEHFVDLLGYCL 584 +G G++G V+Y N VAVK L F+ + +++ + +H V L C Sbjct: 290 LGRGNFGEVFYGKWRNSIDVAVKTLREGT--MSTAAFLQEAAIMKKFRHNRLVALYAVCS 347 Query: 585 EGDQRLLAYEFATMGSLHDIL 647 + + + E+ + GSL D L Sbjct: 348 QEEPIYIVQEYMSKGSLLDFL 368
>SRC_RSVP (P00526) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 42.0 bits (97), Expect = 0.002 Identities = 30/106 (28%), Positives = 50/106 (47%), Gaps = 1/106 (0%) Frame = +3 Query: 339 QVPELSFDELKEKTDDFGSKALVGEGSYGRVYYAVLENGTHVAVKKLDT-SADPEPDNEF 515 Q L+ D + + +A +G+G +G V+ + T VA+K L + PE F Sbjct: 250 QTQGLAKDAWEIPRESLRLEAKLGQGCFGEVWMGTWNDTTRVAIKTLKPGTMSPE---AF 306 Query: 516 IAQVSVISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDILHG 653 + + V+ +L+HE V L E + + E+ + GSL D L G Sbjct: 307 LQEAQVMKKLRHEKLVQLYAVVSE-EPIYIVIEYMSKGSLLDFLKG 351
>ROR1_HUMAN (Q01973) Tyrosine-protein kinase transmembrane receptor ROR1| precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1) Length = 937 Score = 42.0 bits (97), Expect = 0.002 Identities = 24/86 (27%), Positives = 44/86 (51%), Gaps = 5/86 (5%) Frame = +3 Query: 405 VGEGSYGRVYYAVL-----ENGTHVAVKKLDTSADPEPDNEFIAQVSVISRLKHEHFVDL 569 +GE ++G++Y L ++ VA+K L +P+ EF + S+++ L H + V L Sbjct: 479 LGECAFGKIYKGHLYLPGMDHAQLVAIKTLKDYNNPQQWMEFQQEASLMAELHHPNIVCL 538 Query: 570 LGYCLEGDQRLLAYEFATMGSLHDIL 647 LG + + +E+ G LH+ L Sbjct: 539 LGAVTQEQPVCMLFEYINQGDLHEFL 564
>CD2L5_HUMAN (Q14004) Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22)| (CDC2-related protein kinase 5) (Cholinesterase-related cell division controller) Length = 1512 Score = 41.6 bits (96), Expect = 0.002 Identities = 37/122 (30%), Positives = 58/122 (47%), Gaps = 11/122 (9%) Frame = +3 Query: 237 PYEENGDEFPHSPERANGNGFTQIGDQGKAPPSIQVPELSFDELKEKTDDFGSKA----- 401 P GD+ SPE TQ+ K P I P + E KEK D+G + Sbjct: 653 PELPGGDDLSKSPEEKKTA--TQL--HSKRRPKICGPR--YGETKEKDIDWGKRCVDKFD 706 Query: 402 ---LVGEGSYGRVYYA-VLENGTHVAVKK--LDTSADPEPDNEFIAQVSVISRLKHEHFV 563 ++GEG+YG+VY A + G VA+KK LD + P I ++ ++ +L H+ + Sbjct: 707 IIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITA-IREIKILRQLTHQSII 765 Query: 564 DL 569 ++ Sbjct: 766 NM 767
>TAOK2_RAT (Q9JLS3) Serine/threonine-protein kinase TAO2 (EC 2.7.11.1)| (Thousand and one amino acid protein 2) Length = 1235 Score = 41.6 bits (96), Expect = 0.002 Identities = 33/105 (31%), Positives = 50/105 (47%), Gaps = 3/105 (2%) Frame = +3 Query: 342 VPELSFDELKEKTDDFGSKALVGEGSYGRVYYA-VLENGTHVAVKKLDTSA--DPEPDNE 512 V EL F + EK F +G GS+G VY+A + N VA+KK+ S E + Sbjct: 15 VAELFFKDDPEKL--FSDLREIGHGSFGAVYFARDVRNSEVVAIKKMSYSGKQSNEKWQD 72 Query: 513 FIAQVSVISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDIL 647 I +V + +L+H + + G L L E+ +GS D+L Sbjct: 73 IIKEVRFLQKLRHPNTIQYRGCYLREHTAWLVMEYC-LGSASDLL 116
>TAOK2_HUMAN (Q9UL54) Serine/threonine-protein kinase TAO2 (EC 2.7.11.1)| (Thousand and one amino acid protein 2) (Prostate-derived STE20-like kinase 1) (PSK-1) (Kinase from chicken homolog C) (hKFC-C) Length = 1235 Score = 41.6 bits (96), Expect = 0.002 Identities = 33/105 (31%), Positives = 50/105 (47%), Gaps = 3/105 (2%) Frame = +3 Query: 342 VPELSFDELKEKTDDFGSKALVGEGSYGRVYYA-VLENGTHVAVKKLDTSA--DPEPDNE 512 V EL F + EK F +G GS+G VY+A + N VA+KK+ S E + Sbjct: 15 VAELFFKDDPEKL--FSDLREIGHGSFGAVYFARDVRNSEVVAIKKMSYSGKQSNEKWQD 72 Query: 513 FIAQVSVISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDIL 647 I +V + +L+H + + G L L E+ +GS D+L Sbjct: 73 IIKEVRFLQKLRHPNTIQYRGCYLREHTAWLVMEYC-LGSASDLL 116
>MYO3A_HUMAN (Q8NEV4) Myosin IIIA (EC 2.7.11.1)| Length = 1616 Score = 41.6 bits (96), Expect = 0.002 Identities = 31/106 (29%), Positives = 52/106 (49%), Gaps = 7/106 (6%) Frame = +3 Query: 357 FDELKEKTDDFGSKALVGEGSYGRVYYAV-LENGTHVAVKKLDTSADPEPDNEFIAQVSV 533 FD + +D + +G+G+YG+V+ + +NG AVK LD D D E A+ ++ Sbjct: 11 FDNFPDPSDTWEITETIGKGTYGKVFKVLNKKNGQKAAVKILDPIHD--IDEEIEAEYNI 68 Query: 534 ISRLK-HEHFVDLLGYC-----LEGDQRLLAYEFATMGSLHDILHG 653 + L H + V G + GD+ L E + GS+ D++ G Sbjct: 69 LKALSDHPNVVRFYGIYFKKDKVNGDKLWLVLELCSGGSVTDLVKG 114
>TNI3K_PONPY (Q5RF15) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) Length = 617 Score = 41.6 bits (96), Expect = 0.002 Identities = 29/108 (26%), Positives = 52/108 (48%), Gaps = 3/108 (2%) Frame = +3 Query: 336 IQVPELSFDELKEKTDDFGSKALVGEGSYGRVYYAVLENGTHVAVKKL--DTSADPEPDN 509 +Q+ E+ F E+ +G GS+G+VY N VA+K+ +T + Sbjct: 457 LQLSEIEFHEI------------IGSGSFGKVYKGRCRNKI-VAIKRYRANTYCSKSDVD 503 Query: 510 EFIAQVSVISRLKHEHFVDLLGYCL-EGDQRLLAYEFATMGSLHDILH 650 F +VS++ +L H + +G CL + Q + ++ + GSL +LH Sbjct: 504 MFCREVSILCQLNHPCVIQFVGACLNDPSQFAIVTQYISGGSLFSLLH 551
>PAK2_RAT (Q64303) Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1)| (p21-activated kinase 2) (PAK-2) (Gamma-PAK) (p62-PAK) Length = 524 Score = 41.6 bits (96), Expect = 0.002 Identities = 24/82 (29%), Positives = 46/82 (56%), Gaps = 1/82 (1%) Frame = +3 Query: 405 VGEGSYGRVYYAV-LENGTHVAVKKLDTSADPEPDNEFIAQVSVISRLKHEHFVDLLGYC 581 +G+G+ G V+ A + G VA+K+++ P+ + I ++ V+ LK+ + V+ L Sbjct: 255 IGQGASGTVFTATDVALGQEVAIKQINLQKQPKKEL-IINEILVMKELKNPNIVNFLDSY 313 Query: 582 LEGDQRLLAYEFATMGSLHDIL 647 L GD+ + E+ GSL D++ Sbjct: 314 LVGDELFVVMEYLAGGSLTDVV 335
>PAK2_RABIT (Q29502) Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1)| (p21-activated kinase 2) (PAK-2) (Gamma-PAK) (p21-activated protein kinase I) (PAKI) Length = 524 Score = 41.6 bits (96), Expect = 0.002 Identities = 24/82 (29%), Positives = 46/82 (56%), Gaps = 1/82 (1%) Frame = +3 Query: 405 VGEGSYGRVYYAV-LENGTHVAVKKLDTSADPEPDNEFIAQVSVISRLKHEHFVDLLGYC 581 +G+G+ G V+ A + G VA+K+++ P+ + I ++ V+ LK+ + V+ L Sbjct: 255 IGQGASGTVFTATDVALGQEVAIKQINLQKQPKKEL-IINEILVMKELKNPNIVNFLDSY 313 Query: 582 LEGDQRLLAYEFATMGSLHDIL 647 L GD+ + E+ GSL D++ Sbjct: 314 LVGDELFVVMEYLAGGSLTDVV 335
>PAK2_MOUSE (Q8CIN4) Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1)| (p21-activated kinase 2) (PAK-2) Length = 524 Score = 41.6 bits (96), Expect = 0.002 Identities = 24/82 (29%), Positives = 46/82 (56%), Gaps = 1/82 (1%) Frame = +3 Query: 405 VGEGSYGRVYYAV-LENGTHVAVKKLDTSADPEPDNEFIAQVSVISRLKHEHFVDLLGYC 581 +G+G+ G V+ A + G VA+K+++ P+ + I ++ V+ LK+ + V+ L Sbjct: 255 IGQGASGTVFTATDVALGQEVAIKQINLQKQPKKEL-IINEILVMKELKNPNIVNFLDSY 313 Query: 582 LEGDQRLLAYEFATMGSLHDIL 647 L GD+ + E+ GSL D++ Sbjct: 314 LVGDELFVVMEYLAGGSLTDVV 335
>PAK2_HUMAN (Q13177) Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1)| (p21-activated kinase 2) (PAK-2) (PAK65) (Gamma-PAK) (S6/H4 kinase) Length = 524 Score = 41.6 bits (96), Expect = 0.002 Identities = 24/82 (29%), Positives = 46/82 (56%), Gaps = 1/82 (1%) Frame = +3 Query: 405 VGEGSYGRVYYAV-LENGTHVAVKKLDTSADPEPDNEFIAQVSVISRLKHEHFVDLLGYC 581 +G+G+ G V+ A + G VA+K+++ P+ + I ++ V+ LK+ + V+ L Sbjct: 255 IGQGASGTVFTATDVALGQEVAIKQINLQKQPKKEL-IINEILVMKELKNPNIVNFLDSY 313 Query: 582 LEGDQRLLAYEFATMGSLHDIL 647 L GD+ + E+ GSL D++ Sbjct: 314 LVGDELFVVMEYLAGGSLTDVV 335
>TAOK2_MOUSE (Q6ZQ29) Serine/threonine-protein kinase TAO2 (EC 2.7.11.1)| (Thousand and one amino acid protein 2) Length = 1055 Score = 41.6 bits (96), Expect = 0.002 Identities = 33/105 (31%), Positives = 50/105 (47%), Gaps = 3/105 (2%) Frame = +3 Query: 342 VPELSFDELKEKTDDFGSKALVGEGSYGRVYYA-VLENGTHVAVKKLDTSA--DPEPDNE 512 V EL F + EK F +G GS+G VY+A + N VA+KK+ S E + Sbjct: 15 VAELFFKDDPEKL--FSDLREIGHGSFGAVYFARDVRNSEVVAIKKMSYSGKQSNEKWQD 72 Query: 513 FIAQVSVISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDIL 647 I +V + +L+H + + G L L E+ +GS D+L Sbjct: 73 IIKEVRFLQKLRHPNTIQYRGCYLREHTAWLVMEYC-LGSASDLL 116
>TYK2_MOUSE (Q9R117) Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)| Length = 1180 Score = 41.6 bits (96), Expect = 0.002 Identities = 28/88 (31%), Positives = 44/88 (50%), Gaps = 7/88 (7%) Frame = +3 Query: 405 VGEGSYGRVY---YAVLENGTH--VAVKKLDTSADPEPDNEFIAQVSVISRLKHEHFVDL 569 +GEG +G+V Y +GT VAVK L P+ + + ++ ++ L HEH V Sbjct: 896 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKEGCGPQLRSGWQREIEILRTLYHEHIVKY 955 Query: 570 LGYCLEGDQR--LLAYEFATMGSLHDIL 647 G C + ++ L E+ +GSL D L Sbjct: 956 KGCCEDQGEKSVQLVMEYVPLGSLRDYL 983 Score = 35.0 bits (79), Expect = 0.20 Identities = 28/122 (22%), Positives = 48/122 (39%), Gaps = 22/122 (18%) Frame = +3 Query: 336 IQVPELSFDELKEKTDDFGSKALVGEGSYGRVYYAVLENGTHVAVKKLDTSADPEPDNE- 512 + + +LSF + + D+ + +G+G+ VY +L G K+D PEP Sbjct: 570 LNLSQLSFHRVHQ--DEITQLSHLGQGTRTNVYEGLLRVGGPDE-GKVDNGCPPEPGGTS 626 Query: 513 ---------------------FIAQVSVISRLKHEHFVDLLGYCLEGDQRLLAYEFATMG 629 F S++S++ H H L G C+ G + ++ EF G Sbjct: 627 GQQLRVVLKVLDPSHHDIALAFYEXASLMSQVSHMHLAFLHGVCVRGSENIIVTEFVEHG 686 Query: 630 SL 635 L Sbjct: 687 PL 688
>TNI3K_HUMAN (Q59H18) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 936 Score = 41.6 bits (96), Expect = 0.002 Identities = 29/108 (26%), Positives = 52/108 (48%), Gaps = 3/108 (2%) Frame = +3 Query: 336 IQVPELSFDELKEKTDDFGSKALVGEGSYGRVYYAVLENGTHVAVKKL--DTSADPEPDN 509 +Q+ E+ F E+ +G GS+G+VY N VA+K+ +T + Sbjct: 559 LQLSEIEFHEI------------IGSGSFGKVYKGRCRNKI-VAIKRYRANTYCSKSDVD 605 Query: 510 EFIAQVSVISRLKHEHFVDLLGYCL-EGDQRLLAYEFATMGSLHDILH 650 F +VS++ +L H + +G CL + Q + ++ + GSL +LH Sbjct: 606 MFCREVSILCQLNHPCVIQFVGACLNDPSQFAIVTQYISGGSLFSLLH 653
>SRC_RSVH1 (P25020) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 41.6 bits (96), Expect = 0.002 Identities = 30/106 (28%), Positives = 49/106 (46%), Gaps = 1/106 (0%) Frame = +3 Query: 339 QVPELSFDELKEKTDDFGSKALVGEGSYGRVYYAVLENGTHVAVKKLDT-SADPEPDNEF 515 Q L+ D + + +A +G+G +G V+ T VA+K L + PE F Sbjct: 250 QTQGLAKDAWEIPRESLRLEAKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPE---AF 306 Query: 516 IAQVSVISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDILHG 653 + + V+ +L+HE V L E + + E+ + GSL D L G Sbjct: 307 LQEAQVMKKLRHEKLVQLYAVVSE-EPIYIVIEYMSKGSLLDFLKG 351
>KSYK_RAT (Q64725) Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine| kinase) Length = 629 Score = 41.6 bits (96), Expect = 0.002 Identities = 28/85 (32%), Positives = 46/85 (54%), Gaps = 4/85 (4%) Frame = +3 Query: 405 VGEGSYGRV---YYAVLENGTHVAVKKLDTSA-DPEPDNEFIAQVSVISRLKHEHFVDLL 572 +G G++G V YY + + VAVK L A DP +E +A+ +V+ +L + + V ++ Sbjct: 371 LGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRMI 430 Query: 573 GYCLEGDQRLLAYEFATMGSLHDIL 647 G C E + +L E A G L+ L Sbjct: 431 GIC-EAESWMLVMEMAAWGPLNKYL 454
>CC2H3_TRYBB (P54666) Cell division control protein 2 homolog 3 (EC 2.7.11.22)| Length = 311 Score = 41.6 bits (96), Expect = 0.002 Identities = 28/87 (32%), Positives = 47/87 (54%), Gaps = 3/87 (3%) Frame = +3 Query: 366 LKEKTDDFGSKALVGEGSYGRVYYAV-LENGTHVAVKK--LDTSADPEPDNEFIAQVSVI 536 LK++ D + ++GEG+YG VY AV G VA+KK LD + + P + +VS++ Sbjct: 16 LKDQFDRYNRMDILGEGTYGVVYRAVDRATGQIVALKKVRLDRTDEGIPQTA-LREVSIL 74 Query: 537 SRLKHEHFVDLLGYCLEGDQRLLAYEF 617 + H + V+LL + L +E+ Sbjct: 75 QEIHHPNIVNLLDVICADGKLYLIFEY 101
>FGFR1_DROME (Q07407) Fibroblast growth factor receptor homolog 1 precursor (EC| 2.7.10.1) (Protein heartless) Length = 729 Score = 41.6 bits (96), Expect = 0.002 Identities = 25/85 (29%), Positives = 45/85 (52%), Gaps = 1/85 (1%) Frame = +3 Query: 399 ALVGEGSYGRVYYAVLENGTHVAVKKLDTSADPEPDNEFIAQVSVISRL-KHEHFVDLLG 575 A +GEG++GRV A + N VAVK + + + ++ V+ + +H + ++LLG Sbjct: 420 ATLGEGAFGRVVMAEVNNAI-VAVKMVKEGHTDDDIASLVREMEVMKIIGRHINIINLLG 478 Query: 576 YCLEGDQRLLAYEFATMGSLHDILH 650 C + + E+A G+L D L+ Sbjct: 479 CCSQNGPLYVIVEYAPHGNLKDFLY 503
>CDC2_ORYLU (Q9DG98) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 41.6 bits (96), Expect = 0.002 Identities = 26/84 (30%), Positives = 47/84 (55%), Gaps = 2/84 (2%) Frame = +3 Query: 381 DDFGSKALVGEGSYGRVYYAVLEN-GTHVAVKKLDTSADPEP-DNEFIAQVSVISRLKHE 554 +D+ +GEG+YG VY ++ G VA+KK+ ++ E + + +VS++ LKH Sbjct: 2 EDYVKIEKIGEGTYGVVYKGRHKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQELKHP 61 Query: 555 HFVDLLGYCLEGDQRLLAYEFATM 626 + V LL ++ + L +EF +M Sbjct: 62 NVVRLLDVLMQESRLYLIFEFLSM 85
>CDC2_ORYLA (Q9DGD3) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 41.6 bits (96), Expect = 0.002 Identities = 26/84 (30%), Positives = 47/84 (55%), Gaps = 2/84 (2%) Frame = +3 Query: 381 DDFGSKALVGEGSYGRVYYAVLEN-GTHVAVKKLDTSADPEP-DNEFIAQVSVISRLKHE 554 +D+ +GEG+YG VY ++ G VA+KK+ ++ E + + +VS++ LKH Sbjct: 2 EDYVKIEKIGEGTYGVVYKGRHKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQELKHP 61 Query: 555 HFVDLLGYCLEGDQRLLAYEFATM 626 + V LL ++ + L +EF +M Sbjct: 62 NVVRLLDVLMQESRLYLIFEFLSM 85
>CDC2_ORYJA (Q9DGA2) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 41.6 bits (96), Expect = 0.002 Identities = 26/84 (30%), Positives = 47/84 (55%), Gaps = 2/84 (2%) Frame = +3 Query: 381 DDFGSKALVGEGSYGRVYYAVLEN-GTHVAVKKLDTSADPEP-DNEFIAQVSVISRLKHE 554 +D+ +GEG+YG VY ++ G VA+KK+ ++ E + + +VS++ LKH Sbjct: 2 EDYVKIEKIGEGTYGVVYKGRHKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQELKHP 61 Query: 555 HFVDLLGYCLEGDQRLLAYEFATM 626 + V LL ++ + L +EF +M Sbjct: 62 NVVRLLDVLMQESRLYLIFEFLSM 85
>CDC2_ORYCU (Q9DGA5) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 41.6 bits (96), Expect = 0.002 Identities = 26/84 (30%), Positives = 47/84 (55%), Gaps = 2/84 (2%) Frame = +3 Query: 381 DDFGSKALVGEGSYGRVYYAVLEN-GTHVAVKKLDTSADPEP-DNEFIAQVSVISRLKHE 554 +D+ +GEG+YG VY ++ G VA+KK+ ++ E + + +VS++ LKH Sbjct: 2 EDYVKIEKIGEGTYGVVYKGRHKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQELKHP 61 Query: 555 HFVDLLGYCLEGDQRLLAYEFATM 626 + V LL ++ + L +EF +M Sbjct: 62 NVVRLLDVLMQESRLYLIFEFLSM 85
>FLT3_HUMAN (P36888) FL cytokine receptor precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor FLT3) (Stem cell tyrosine kinase 1) (STK-1) (CD135 antigen) Length = 993 Score = 41.2 bits (95), Expect = 0.003 Identities = 29/102 (28%), Positives = 51/102 (50%), Gaps = 7/102 (6%) Frame = +3 Query: 363 ELKEKTDDFGSKALVGEGSYGRVY----YAVLENGT--HVAVKKLDTSADPEPDNEFIAQ 524 E + +FG ++G G++G+V Y + + G VAVK L AD +++ Sbjct: 604 EFPRENLEFGK--VLGSGAFGKVMNATAYGISKTGVSIQVAVKMLKEKADSSEREALMSE 661 Query: 525 VSVISRL-KHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDIL 647 + ++++L HE+ V+LLG C L +E+ G L + L Sbjct: 662 LKMMTQLGSHENIVNLLGACTLSGPIYLIFEYCCYGDLLNYL 703
>CSF1R_FELCA (P13369) Macrophage colony-stimulating factor 1 receptor precursor| (CSF-1-R) (EC 2.7.10.1) (Fms proto-oncogene) (c-fms) Length = 980 Score = 41.2 bits (95), Expect = 0.003 Identities = 36/131 (27%), Positives = 58/131 (44%), Gaps = 7/131 (5%) Frame = +3 Query: 276 ERANGNGFTQIGDQGKAPPSIQVPELSFDELKEKTDDFGSKALVGEGSYGRVYYAVL--- 446 E GN +T I Q+P E FG +G G++G+V A Sbjct: 551 ESYEGNSYTFIDPT-------QLPYNEKWEFPRNNLQFGKT--LGAGAFGKVVEATAFGL 601 Query: 447 ---ENGTHVAVKKLDTSADPEPDNEFIAQVSVISRL-KHEHFVDLLGYCLEGDQRLLAYE 614 + VAVK L ++A + ++++ ++S L +HE+ V+LLG C G L+ E Sbjct: 602 GKEDAVLKVAVKMLKSTAHADEKEALMSELKIMSHLGQHENIVNLLGACTHGGPVLVITE 661 Query: 615 FATMGSLHDIL 647 + G L + L Sbjct: 662 YCCYGDLLNFL 672
>CDK2_XENLA (P23437) Cell division protein kinase 2 (EC 2.7.11.22) (CDC2| homolog Eg1 protein kinase) Length = 297 Score = 41.2 bits (95), Expect = 0.003 Identities = 29/82 (35%), Positives = 43/82 (52%), Gaps = 3/82 (3%) Frame = +3 Query: 381 DDFGSKALVGEGSYGRVYYAV-LENGTHVAVKK--LDTSADPEPDNEFIAQVSVISRLKH 551 ++F +GEG+YG VY A E G VA+KK LDT + P I ++S++ L H Sbjct: 2 ENFQKVEKIGEGTYGVVYKARNRETGEIVALKKIRLDTETEGVPSTA-IREISLLKELNH 60 Query: 552 EHFVDLLGYCLEGDQRLLAYEF 617 + V LL ++ L +EF Sbjct: 61 PNIVKLLDVIHTENKLYLVFEF 82
>CSF1R_HUMAN (P07333) Macrophage colony-stimulating factor 1 receptor precursor| (CSF-1-R) (EC 2.7.10.1) (Fms proto-oncogene) (c-fms) (CD115 antigen) Length = 972 Score = 41.2 bits (95), Expect = 0.003 Identities = 36/131 (27%), Positives = 58/131 (44%), Gaps = 7/131 (5%) Frame = +3 Query: 276 ERANGNGFTQIGDQGKAPPSIQVPELSFDELKEKTDDFGSKALVGEGSYGRVYYAVL--- 446 E GN +T I Q+P E FG +G G++G+V A Sbjct: 554 ESYEGNSYTFIDPT-------QLPYNEKWEFPRNNLQFGKT--LGAGAFGKVVEATAFGL 604 Query: 447 ---ENGTHVAVKKLDTSADPEPDNEFIAQVSVISRL-KHEHFVDLLGYCLEGDQRLLAYE 614 + VAVK L ++A + ++++ ++S L +HE+ V+LLG C G L+ E Sbjct: 605 GKEDAVLKVAVKMLKSTAHADEKEALMSELKIMSHLGQHENIVNLLGACTHGGPVLVITE 664 Query: 615 FATMGSLHDIL 647 + G L + L Sbjct: 665 YCCYGDLLNFL 675
>CSK_CHICK (P41239) Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase)| Length = 450 Score = 41.2 bits (95), Expect = 0.003 Identities = 28/83 (33%), Positives = 44/83 (53%), Gaps = 1/83 (1%) Frame = +3 Query: 402 LVGEGSYGRVYYAVLENGTHVAVKKLDTSADPEPDNEFIAQVSVISRLKHEHFVDLLGYC 581 ++G+G +G V G VAVK + A + F+A+ SV+++L+H + V LLG Sbjct: 200 IIGKGEFGDVMLGDYR-GNKVAVKCIKNDATAQA---FLAEASVMTQLRHSNLVQLLGVI 255 Query: 582 LEGDQRL-LAYEFATMGSLHDIL 647 +E L + E+ GSL D L Sbjct: 256 VEEKSGLYIVTEYMAKGSLVDYL 278
>PAK4_MOUSE (Q8BTW9) Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1)| (p21-activated kinase 4) (PAK-4) Length = 593 Score = 41.2 bits (95), Expect = 0.003 Identities = 29/82 (35%), Positives = 44/82 (53%), Gaps = 1/82 (1%) Frame = +3 Query: 405 VGEGSYGRVYYA-VLENGTHVAVKKLDTSADPEPDNEFIAQVSVISRLKHEHFVDLLGYC 581 +GEGS G V A V +G VAVKK+D + F +V ++ +HE+ V++ Sbjct: 329 IGEGSTGIVCIATVRSSGKLVAVKKMDLRKQQRRELLF-NEVVIMRDYRHENVVEMYNSY 387 Query: 582 LEGDQRLLAYEFATMGSLHDIL 647 L GD+ + EF G+L DI+ Sbjct: 388 LVGDELWVVMEFLEGGALTDIV 409
>KFMS_FSVMD (P00545) Tyrosine-protein kinase transforming protein fms (EC| 2.7.10.1) Length = 978 Score = 41.2 bits (95), Expect = 0.003 Identities = 36/131 (27%), Positives = 58/131 (44%), Gaps = 7/131 (5%) Frame = +3 Query: 276 ERANGNGFTQIGDQGKAPPSIQVPELSFDELKEKTDDFGSKALVGEGSYGRVYYAVL--- 446 E GN +T I Q+P E FG +G G++G+V A Sbjct: 585 ESYEGNSYTFIDPT-------QLPYNEKWEFPRNNLQFGKT--LGTGAFGKVVEATAFGL 635 Query: 447 ---ENGTHVAVKKLDTSADPEPDNEFIAQVSVISRL-KHEHFVDLLGYCLEGDQRLLAYE 614 + VAVK L ++A + ++++ ++S L +HE+ V+LLG C G L+ E Sbjct: 636 GKEDAVLKVAVKMLKSTAHADEKEALMSELKIMSHLGQHENIVNLLGACTHGGPVLVITE 695 Query: 615 FATMGSLHDIL 647 + G L + L Sbjct: 696 YCCYGDLLNFL 706
>JAK3_MOUSE (Q62137) Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3)| (JAK-3) Length = 1299 Score = 41.2 bits (95), Expect = 0.003 Identities = 37/135 (27%), Positives = 64/135 (47%), Gaps = 11/135 (8%) Frame = +3 Query: 264 PHSPERAN----GNGFTQIGDQGKAPPSIQVPELSFDELKEKTDDFGSKALVGEGSYGRV 431 P E++N G T G +P + +LSF + TD G + L G GS+ ++ Sbjct: 690 PRPKEKSNLIVVRRGCTPAPAPGCSPSCCALTQLSFHTIP--TDSLGHENL-GHGSFTKI 746 Query: 432 YYA----VLENGTH---VAVKKLDTSADPEPDNEFIAQVSVISRLKHEHFVDLLGYCLEG 590 + V++ TH V +K +D S F+ S++S++ + H V L G C+ G Sbjct: 747 FRGRRREVVDGETHDSEVLLKVMD-SRHRNCMESFLEAASLMSQVSYPHLVLLHGVCMAG 805 Query: 591 DQRLLAYEFATMGSL 635 D ++ EF +G++ Sbjct: 806 DS-IMVQEFVYLGAI 819
>TXK_MOUSE (P42682) Tyrosine-protein kinase TXK (EC 2.7.10.2) (PTK-RL-18)| (Resting lymphocyte kinase) Length = 527 Score = 41.2 bits (95), Expect = 0.003 Identities = 24/81 (29%), Positives = 37/81 (45%) Frame = +3 Query: 405 VGEGSYGRVYYAVLENGTHVAVKKLDTSADPEPDNEFIAQVSVISRLKHEHFVDLLGYCL 584 +G G +G V+ VA+K ++ + E D FI + V+ +L H V L G C+ Sbjct: 277 IGSGQFGVVHLGEWRAHIPVAIKAINEGSMSEED--FIEEAKVMMKLSHSRLVQLYGVCI 334 Query: 585 EGDQRLLAYEFATMGSLHDIL 647 + + EF G L D L Sbjct: 335 QQKPLYIVTEFMENGCLLDYL 355
>NRKA_TRYBB (Q08942) Putative serine/threonine-protein kinase A (EC 2.7.11.1)| Length = 431 Score = 41.2 bits (95), Expect = 0.003 Identities = 24/85 (28%), Positives = 44/85 (51%), Gaps = 2/85 (2%) Frame = +3 Query: 393 SKALVGEGSYGRVYYA-VLENGTHVAVKKLDTSADPEPDNEFI-AQVSVISRLKHEHFVD 566 +K +VG GSYG Y A +E+G+ K +D S + D + +++ ++ H + + Sbjct: 22 NKGIVGLGSYGEAYVAESVEDGSLCVAKVMDLSKMSQRDKRYAQSEIKCLANCNHPNIIR 81 Query: 567 LLGYCLEGDQRLLAYEFATMGSLHD 641 + E D+ L+ EFA G+L + Sbjct: 82 YIEDHEENDRLLIVMEFADSGNLDE 106
>TXK_HUMAN (P42681) Tyrosine-protein kinase TXK (EC 2.7.10.2)| Length = 527 Score = 40.8 bits (94), Expect = 0.004 Identities = 23/81 (28%), Positives = 38/81 (46%) Frame = +3 Query: 405 VGEGSYGRVYYAVLENGTHVAVKKLDTSADPEPDNEFIAQVSVISRLKHEHFVDLLGYCL 584 +G G +G V+ + VA+K ++ + E D FI + V+ +L H V L G C+ Sbjct: 277 IGSGQFGVVHLGEWRSHIQVAIKAINEGSMSEED--FIEEAKVMMKLSHSKLVQLYGVCI 334 Query: 585 EGDQRLLAYEFATMGSLHDIL 647 + + EF G L + L Sbjct: 335 QRKPLYIVTEFMENGCLLNYL 355
>FGFR1_RAT (Q04589) Basic fibroblast growth factor receptor 1 precursor (EC| 2.7.10.1) (FGFR-1) (bFGF-R) (MFR) Length = 822 Score = 40.8 bits (94), Expect = 0.004 Identities = 25/90 (27%), Positives = 48/90 (53%), Gaps = 9/90 (10%) Frame = +3 Query: 405 VGEGSYGRVYYAVL--------ENGTHVAVKKLDTSADPEPDNEFIAQVSVISRL-KHEH 557 +GEG +G+V A T VAVK L + A + ++ I+++ ++ + KH++ Sbjct: 484 LGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKN 543 Query: 558 FVDLLGYCLEGDQRLLAYEFATMGSLHDIL 647 ++LLG C + + E+A+ G+L + L Sbjct: 544 IINLLGACTQDGPLYVIVEYASKGNLREYL 573
>FGFR1_MOUSE (P16092) Basic fibroblast growth factor receptor 1 precursor (EC| 2.7.10.1) (FGFR-1) (bFGF-R) (MFR) Length = 822 Score = 40.8 bits (94), Expect = 0.004 Identities = 25/90 (27%), Positives = 48/90 (53%), Gaps = 9/90 (10%) Frame = +3 Query: 405 VGEGSYGRVYYAVL--------ENGTHVAVKKLDTSADPEPDNEFIAQVSVISRL-KHEH 557 +GEG +G+V A T VAVK L + A + ++ I+++ ++ + KH++ Sbjct: 484 LGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKN 543 Query: 558 FVDLLGYCLEGDQRLLAYEFATMGSLHDIL 647 ++LLG C + + E+A+ G+L + L Sbjct: 544 IINLLGACTQDGPLYVIVEYASKGNLREYL 573
>FGFR1_HUMAN (P11362) Basic fibroblast growth factor receptor 1 precursor (EC| 2.7.10.1) (FGFR-1) (bFGF-R) (Fms-like tyrosine kinase 2) (c-fgr) (CD331 antigen) Length = 822 Score = 40.8 bits (94), Expect = 0.004 Identities = 25/90 (27%), Positives = 48/90 (53%), Gaps = 9/90 (10%) Frame = +3 Query: 405 VGEGSYGRVYYAVL--------ENGTHVAVKKLDTSADPEPDNEFIAQVSVISRL-KHEH 557 +GEG +G+V A T VAVK L + A + ++ I+++ ++ + KH++ Sbjct: 484 LGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKN 543 Query: 558 FVDLLGYCLEGDQRLLAYEFATMGSLHDIL 647 ++LLG C + + E+A+ G+L + L Sbjct: 544 IINLLGACTQDGPLYVIVEYASKGNLREYL 573
>IRAK3_HUMAN (Q9Y616) Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1)| (IRAK-3) (IL-1 receptor-associated kinase M) (IRAK-M) Length = 596 Score = 40.8 bits (94), Expect = 0.004 Identities = 28/102 (27%), Positives = 48/102 (47%), Gaps = 3/102 (2%) Frame = +3 Query: 351 LSFDELKEKTDDFGSKALVGEGSYGRVYYAVLENGTHVAVKKLDTSADPEPD---NEFIA 521 +SF + E T +F L+GEG VY ++N T+ AVK + F++ Sbjct: 153 ISFQNIIEGTRNFHKDFLIGEGEIFEVYRVEIQNLTY-AVKLFKQEKKMQCKKHWKRFLS 211 Query: 522 QVSVISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDIL 647 ++ V+ H + ++L Y E ++ L Y + G+L D L Sbjct: 212 ELEVLLLFHHPNILELAAYFTETEKFCLIYPYMRNGTLFDRL 253
>FPS_DROME (P18106) Tyrosine-protein kinase Fps85D (EC 2.7.10.2) (dFer)| Length = 1325 Score = 40.8 bits (94), Expect = 0.004 Identities = 24/86 (27%), Positives = 42/86 (48%), Gaps = 1/86 (1%) Frame = +3 Query: 381 DDFGSKALVGEGSYGRVYYAVLENGT-HVAVKKLDTSADPEPDNEFIAQVSVISRLKHEH 557 DD +G G++G VY A L++ VAVK + E +F+ + ++ + H + Sbjct: 1061 DDVVLLERIGRGNFGDVYKAKLKSTKLDVAVKTCRMTLPDEQKRKFLQEGRILKQYDHPN 1120 Query: 558 FVDLLGYCLEGDQRLLAYEFATMGSL 635 V L+G C++ ++ E GSL Sbjct: 1121 IVKLIGICVQKQPIMIVMELVLGGSL 1146
>PAK1_MOUSE (O88643) Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1)| (p21-activated kinase 1) (PAK-1) (P65-PAK) (Alpha-PAK) (CDC42/RAC effector kinase PAK-A) Length = 545 Score = 40.8 bits (94), Expect = 0.004 Identities = 30/112 (26%), Positives = 56/112 (50%), Gaps = 11/112 (9%) Frame = +3 Query: 345 PELSFDELKEKTDDFGSKA----------LVGEGSYGRVYYAV-LENGTHVAVKKLDTSA 491 P++S +E+ EK S +G+G+ G VY A+ + G VA+K+++ Sbjct: 246 PKMSDEEILEKLRSIVSVGDPKKKYTPFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQ 305 Query: 492 DPEPDNEFIAQVSVISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDIL 647 P+ + I ++ V+ K+ + V+ L L GD+ + E+ GSL D++ Sbjct: 306 QPKKEL-IINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVV 356
>PAK1_HUMAN (Q13153) Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1)| (p21-activated kinase 1) (PAK-1) (P65-PAK) (Alpha-PAK) Length = 545 Score = 40.8 bits (94), Expect = 0.004 Identities = 30/112 (26%), Positives = 56/112 (50%), Gaps = 11/112 (9%) Frame = +3 Query: 345 PELSFDELKEKTDDFGSKA----------LVGEGSYGRVYYAV-LENGTHVAVKKLDTSA 491 P++S +E+ EK S +G+G+ G VY A+ + G VA+K+++ Sbjct: 246 PKMSDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQ 305 Query: 492 DPEPDNEFIAQVSVISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDIL 647 P+ + I ++ V+ K+ + V+ L L GD+ + E+ GSL D++ Sbjct: 306 QPKKEL-IINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVV 356
>PAK1_RAT (P35465) Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1)| (p21-activated kinase 1) (PAK-1) (P68-PAK) (Alpha-PAK) (Protein kinase MUK2) Length = 544 Score = 40.8 bits (94), Expect = 0.004 Identities = 30/112 (26%), Positives = 56/112 (50%), Gaps = 11/112 (9%) Frame = +3 Query: 345 PELSFDELKEKTDDFGSKA----------LVGEGSYGRVYYAV-LENGTHVAVKKLDTSA 491 P++S +E+ EK S +G+G+ G VY A+ + G VA+K+++ Sbjct: 245 PKMSDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQ 304 Query: 492 DPEPDNEFIAQVSVISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDIL 647 P+ + I ++ V+ K+ + V+ L L GD+ + E+ GSL D++ Sbjct: 305 QPKKEL-IINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVV 355
>ABL1_CAEEL (P03949) Tyrosine-protein kinase abl-1 (EC 2.7.10.2)| Length = 1224 Score = 40.8 bits (94), Expect = 0.004 Identities = 27/82 (32%), Positives = 42/82 (51%), Gaps = 1/82 (1%) Frame = +3 Query: 405 VGEGSYGRVYYAVLE-NGTHVAVKKLDTSADPEPDNEFIAQVSVISRLKHEHFVDLLGYC 581 +G G YG VY + + +AVK L D P +EF+A+ +++ L H++ V LLG C Sbjct: 317 LGGGQYGDVYEGYWKRHDCTIAVKAL--KEDAMPLHEFLAEAAIMKDLHHKNLVRLLGVC 374 Query: 582 LEGDQRLLAYEFATMGSLHDIL 647 + EF G+L + L Sbjct: 375 THEAPFYIITEFMCNGNLLEYL 396
>CDC2_CARAU (P51958) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 302 Score = 40.8 bits (94), Expect = 0.004 Identities = 25/84 (29%), Positives = 46/84 (54%), Gaps = 2/84 (2%) Frame = +3 Query: 381 DDFGSKALVGEGSYGRVYYAVLEN-GTHVAVKKLDTSADPEP-DNEFIAQVSVISRLKHE 554 DD+ +GEG+YG VY + G VA+KK+ ++ E + + ++S++ L+H Sbjct: 2 DDYLKIEKIGEGTYGVVYKGRNKTTGQVVAMKKIRLESEEEGVPSTAVREISLLKELQHP 61 Query: 555 HFVDLLGYCLEGDQRLLAYEFATM 626 + V LL ++ + L +EF +M Sbjct: 62 NVVRLLDVLMQESKLYLVFEFLSM 85
>SRK3_SPOLA (P42689) Tyrosine-protein kinase SRK3 (EC 2.7.10.2) (Fragment)| Length = 334 Score = 40.8 bits (94), Expect = 0.004 Identities = 24/84 (28%), Positives = 41/84 (48%), Gaps = 1/84 (1%) Frame = +3 Query: 405 VGEGSYGRVYYAVLENGTHVAVKKLDTSADPEPDNEFIAQVSVISRLKHEHFVDLLGYCL 584 +G+G++G V+ V T VAVK L D +F+ + V+ ++ H + + L C Sbjct: 72 LGQGNFGEVWAGVWNGTTAVAVKTL--KPDTMEVKDFVQEAQVMKKIHHPNLLQLYAVCT 129 Query: 585 EGDQRLLAYEFATMGSLHDIL-HG 653 G+ + E GS+ + L HG Sbjct: 130 IGEPIYIVTELMKYGSMLEYLKHG 153
>PAK4_HUMAN (O96013) Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1)| (p21-activated kinase 4) (PAK-4) Length = 591 Score = 40.8 bits (94), Expect = 0.004 Identities = 29/82 (35%), Positives = 44/82 (53%), Gaps = 1/82 (1%) Frame = +3 Query: 405 VGEGSYGRVYYA-VLENGTHVAVKKLDTSADPEPDNEFIAQVSVISRLKHEHFVDLLGYC 581 +GEGS G V A V +G VAVKK+D + F +V ++ +HE+ V++ Sbjct: 327 IGEGSTGIVCIATVRSSGKLVAVKKMDLRKQQRRELLF-NEVVIMRDYQHENVVEMYNSY 385 Query: 582 LEGDQRLLAYEFATMGSLHDIL 647 L GD+ + EF G+L DI+ Sbjct: 386 LVGDELWVVMEFLEGGALTDIV 407
>FGFR1_CHICK (P21804) Basic fibroblast growth factor receptor 1 precursor (EC| 2.7.10.1) Length = 819 Score = 40.8 bits (94), Expect = 0.004 Identities = 25/90 (27%), Positives = 48/90 (53%), Gaps = 9/90 (10%) Frame = +3 Query: 405 VGEGSYGRVYYAVL--------ENGTHVAVKKLDTSADPEPDNEFIAQVSVISRL-KHEH 557 +GEG +G+V A T VAVK L + A + ++ I+++ ++ + KH++ Sbjct: 482 LGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKN 541 Query: 558 FVDLLGYCLEGDQRLLAYEFATMGSLHDIL 647 ++LLG C + + E+A+ G+L + L Sbjct: 542 IINLLGACTQDGPLYVIVEYASKGNLREYL 571
>TESK1_RAT (Q63572) Dual specificity testis-specific protein kinase 1 (EC| 2.7.12.1) (Testicular protein kinase 1) Length = 628 Score = 40.8 bits (94), Expect = 0.004 Identities = 32/132 (24%), Positives = 53/132 (40%), Gaps = 7/132 (5%) Frame = +3 Query: 273 PERANGNGFTQI-------GDQGKAPPSIQVPELSFDELKEKTDDFGSKALVGEGSYGRV 431 P R G G T + G G+ PS S + DDF +G G + V Sbjct: 7 PLRGPGPGETPVEGPGGAGGGPGRGRPSSYRALRSAVSSLARVDDFDCAEKIGAGFFSEV 66 Query: 432 YYAVLENGTHVAVKKLDTSADPEPDNEFIAQVSVISRLKHEHFVDLLGYCLEGDQRLLAY 611 Y V V K++ P + + +V +++RL+H + + +G C+ Q Sbjct: 67 YKVRHRQSGQVMVLKMNKL--PSNRSNTLREVQLMNRLRHPNILRFMGVCVHQGQLHALT 124 Query: 612 EFATMGSLHDIL 647 E+ G+L +L Sbjct: 125 EYMNGGTLEQLL 136
>CDC2H_PLAYO (Q7RM49) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 289 Score = 40.4 bits (93), Expect = 0.005 Identities = 22/72 (30%), Positives = 37/72 (51%), Gaps = 2/72 (2%) Frame = +3 Query: 405 VGEGSYGRVYYAVLENGTHVAVKKLDTSADPE--PDNEFIAQVSVISRLKHEHFVDLLGY 578 +GEG+YG VY A +G A+KK+ + E P I ++S++ L+H + V L Sbjct: 10 IGEGTYGVVYKAQNSDGESFALKKIRLEKEDEGIPSTVSIREISILKELRHSNIVKLYDV 69 Query: 579 CLEGDQRLLAYE 614 + +L +E Sbjct: 70 IHAKKRLILVFE 81
>SRC42_DROME (Q9V9J3) Tyrosine-protein kinase Src42A (EC 2.7.10.2) (Dsrc41)| Length = 517 Score = 40.4 bits (93), Expect = 0.005 Identities = 23/82 (28%), Positives = 41/82 (50%), Gaps = 1/82 (1%) Frame = +3 Query: 405 VGEGSYGRVYYAVLENGTHVAVKKLDTSA-DPEPDNEFIAQVSVISRLKHEHFVDLLGYC 581 +G G +G V+ + N T VA+K L + DP+ +F+A+ ++ +L+H + L C Sbjct: 254 LGSGQFGDVWEGLWNNTTPVAIKTLKSGTMDPK---DFLAEAQIMKKLRHTKLIQLYAVC 310 Query: 582 LEGDQRLLAYEFATMGSLHDIL 647 + + E GSL + L Sbjct: 311 TVEEPIYIITELMKHGSLLEYL 332
>PR2_DROME (Q9I7F7) Tyrosine-protein kinase PR2 (EC 2.7.10.2)| Length = 1337 Score = 40.4 bits (93), Expect = 0.005 Identities = 27/92 (29%), Positives = 41/92 (44%), Gaps = 3/92 (3%) Frame = +3 Query: 381 DDFGSKALVGEGSYGRVYYAVLENGTH---VAVKKLDTSADPEPDNEFIAQVSVISRLKH 551 D +G G +G V V NG VA+K L EF+ + +++ ++H Sbjct: 131 DSISVNKQLGTGEFGIVQQGVWSNGNERIQVAIKCLCRERMQSNPMEFLKEAAIMHSIEH 190 Query: 552 EHFVDLLGYCLEGDQRLLAYEFATMGSLHDIL 647 E+ V L G L D +L E A + SL + L Sbjct: 191 ENIVRLYGVVLATDSLMLVTELAHLRSLLECL 222
>MET_RAT (P97523) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1382 Score = 40.4 bits (93), Expect = 0.005 Identities = 23/87 (26%), Positives = 42/87 (48%), Gaps = 5/87 (5%) Frame = +3 Query: 402 LVGEGSYGRVYYAVLENGT----HVAVKKLDTSADPEPDNEFIAQVSVISRLKHEHFVDL 569 ++G G +G VY+ L + H AVK L+ D E ++F+ + ++ H + + L Sbjct: 1084 VIGRGHFGCVYHGTLLDSDGKKIHCAVKSLNRITDIEEVSQFLTEGIIMKDFSHPNVLSL 1143 Query: 570 LGYCLEGD-QRLLAYEFATMGSLHDIL 647 LG CL + L+ + G L + + Sbjct: 1144 LGICLRSEGSPLVVLPYMKHGDLRNFI 1170
>M4K3_RAT (Q924I2) Mitogen-activated protein kinase kinase kinase kinase 3| (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 3) (MEK kinase kinase 3) (MEKKK 3) (Germinal center kinase-related protein kinase) (GLK) (Fragment) Length = 862 Score = 40.4 bits (93), Expect = 0.005 Identities = 29/91 (31%), Positives = 42/91 (46%), Gaps = 1/91 (1%) Frame = +3 Query: 381 DDFGSKALVGEGSYGRVYYAVLENGTHVAVKKLDTSADPEPDNEFIAQVSVISR-LKHEH 557 +DF +G G+YG VY A N +A K+ +P D + Q ++ + KH + Sbjct: 3 EDFELIQRIGSGTYGDVYKARNVNTGELAAIKV-IKLEPGEDFAVVQQEIIMMKDCKHAN 61 Query: 558 FVDLLGYCLEGDQRLLAYEFATMGSLHDILH 650 V G L D+ + EF GSL DI H Sbjct: 62 IVAYFGSYLRRDKLWICMEFCGGGSLQDIYH 92
>M3LK7_DROME (P83104) Putative mitogen-activated protein kinase kinase kinase| 7-like (EC 2.7.11.25) Length = 393 Score = 40.4 bits (93), Expect = 0.005 Identities = 30/104 (28%), Positives = 51/104 (49%) Frame = +3 Query: 342 VPELSFDELKEKTDDFGSKALVGEGSYGRVYYAVLENGTHVAVKKLDTSADPEPDNEFIA 521 V ++ F E+K S+ +G GS G V A +N +AVK D + N Sbjct: 2 VKQVDFAEVKL------SEKFLGAGSGGAVRKATFQN-QEIAVKIFDFLEETIKKNAE-R 53 Query: 522 QVSVISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDILHG 653 +++ +S + HE+ + ++G G + L E+ GSLH+ L+G Sbjct: 54 EITHLSEIDHENVIRVIGRASNGKKDYLLMEYLEEGSLHNYLYG 97
>STK10_HUMAN (O94804) Serine/threonine-protein kinase 10 (EC 2.7.11.1)| (Lymphocyte-oriented kinase) Length = 968 Score = 40.4 bits (93), Expect = 0.005 Identities = 22/82 (26%), Positives = 45/82 (54%), Gaps = 1/82 (1%) Frame = +3 Query: 405 VGEGSYGRVYYAV-LENGTHVAVKKLDTSADPEPDNEFIAQVSVISRLKHEHFVDLLGYC 581 +G+G++G+VY A E G A K ++T ++ E + ++I ++ +++ H + V LLG Sbjct: 42 LGDGAFGKVYKAKNKETGALAAAKVIETKSEEELE-DYIVEIEILATCDHPYIVKLLGAY 100 Query: 582 LEGDQRLLAYEFATMGSLHDIL 647 + + EF G++ I+ Sbjct: 101 YHDGKLWIMIEFCPGGAVDAIM 122
>JAK1_BRARE (O12990) Tyrosine-protein kinase Jak1 (EC 2.7.10.2) (Janus kinase 1)| (Jak-1) Length = 1153 Score = 40.4 bits (93), Expect = 0.005 Identities = 37/117 (31%), Positives = 48/117 (41%), Gaps = 8/117 (6%) Frame = +3 Query: 321 KAPPSIQ-VPELSFDELKEKTDDFGSKALVGEGSYGRVYYAVLE-----NGTHVAVKKLD 482 K PSIQ VP L D + +GEG +G+V + G VAVK L Sbjct: 849 KQNPSIQPVPMLEVDPTVFEKRFLKKIRDLGEGHFGKVELCRYDPRGDRTGELVAVKSLK 908 Query: 483 TSADPEPDNEFIAQVSVISRLKHEHFVDLLGYCLE--GDQRLLAYEFATMGSLHDIL 647 E N ++ ++ L HE+ V G C E G L EF GSL + L Sbjct: 909 PENREEQSNNLWREIHILRELYHENIVKYKGICNEEGGRSIKLIMEFLPAGSLKEYL 965 Score = 32.3 bits (72), Expect = 1.3 Identities = 27/111 (24%), Positives = 47/111 (42%), Gaps = 12/111 (10%) Frame = +3 Query: 339 QVPELSFDELKEKTDDFGSKALVGEGSYGRVYYAVLE---------NGTHVAVK---KLD 482 QV +LSFD + ++ G +G G+ +Y +L+ G VK K+ Sbjct: 566 QVSQLSFDRILKEEIVQGEH--LGRGTRTNIYAGILKPKSDDEDDLGGYSQEVKVVLKVL 623 Query: 483 TSADPEPDNEFIAQVSVISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSL 635 S + F S++ ++ H+H L G C+ + ++ EF G L Sbjct: 624 GSGHRDISLAFFETASMMRQISHKHTALLYGVCVRHQENIMVEEFVQYGPL 674
>M4K3_MOUSE (Q99JP0) Mitogen-activated protein kinase kinase kinase kinase 3| (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 3) (MEK kinase kinase 3) (MEKKK 3) (Germinal center kinase-related protein kinase) (GLK) (Fragments) Length = 681 Score = 40.4 bits (93), Expect = 0.005 Identities = 29/91 (31%), Positives = 42/91 (46%), Gaps = 1/91 (1%) Frame = +3 Query: 381 DDFGSKALVGEGSYGRVYYAVLENGTHVAVKKLDTSADPEPDNEFIAQVSVISR-LKHEH 557 +DF +G G+YG VY A N +A K+ +P D + Q ++ + KH + Sbjct: 14 EDFELIQRIGSGTYGDVYKARNVNTGELAAIKV-IKLEPGEDFAVVQQEIIMMKDCKHPN 72 Query: 558 FVDLLGYCLEGDQRLLAYEFATMGSLHDILH 650 V G L D+ + EF GSL DI H Sbjct: 73 IVAYFGSYLRRDKLWICMEFCGGGSLQDIYH 103
>MET_MOUSE (P16056) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1379 Score = 40.4 bits (93), Expect = 0.005 Identities = 23/87 (26%), Positives = 42/87 (48%), Gaps = 5/87 (5%) Frame = +3 Query: 402 LVGEGSYGRVYYAVLENGT----HVAVKKLDTSADPEPDNEFIAQVSVISRLKHEHFVDL 569 ++G G +G VY+ L + H AVK L+ D E ++F+ + ++ H + + L Sbjct: 1081 VIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIEEVSQFLTEGIIMKDFSHPNVLSL 1140 Query: 570 LGYCLEGD-QRLLAYEFATMGSLHDIL 647 LG CL + L+ + G L + + Sbjct: 1141 LGICLRSEGSPLVVLPYMKHGDLRNFI 1167
>M4K3_HUMAN (Q8IVH8) Mitogen-activated protein kinase kinase kinase kinase 3| (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 3) (MEK kinase kinase 3) (MEKKK 3) (Germinal center kinase-related protein kinase) (GLK) Length = 894 Score = 40.4 bits (93), Expect = 0.005 Identities = 29/91 (31%), Positives = 42/91 (46%), Gaps = 1/91 (1%) Frame = +3 Query: 381 DDFGSKALVGEGSYGRVYYAVLENGTHVAVKKLDTSADPEPDNEFIAQVSVISR-LKHEH 557 +DF +G G+YG VY A N +A K+ +P D + Q ++ + KH + Sbjct: 14 EDFELIQRIGSGTYGDVYKARNVNTGELAAIKV-IKLEPGEDFAVVQQEIIMMKDCKHPN 72 Query: 558 FVDLLGYCLEGDQRLLAYEFATMGSLHDILH 650 V G L D+ + EF GSL DI H Sbjct: 73 IVAYFGSYLRRDKLWICMEFCGGGSLQDIYH 103
>MIPR_LYMST (Q25410) Putative molluscan insulin-related peptide(s) receptor| precursor (EC 2.7.10.1) [Contains: Putative molluscan insulin-related peptide(s) receptor alpha chain; Putative molluscan insulin-related peptide(s) receptor beta chain] Length = 1607 Score = 40.4 bits (93), Expect = 0.005 Identities = 26/90 (28%), Positives = 39/90 (43%), Gaps = 7/90 (7%) Frame = +3 Query: 405 VGEGSYGRVYYAVLEN-------GTHVAVKKLDTSADPEPDNEFIAQVSVISRLKHEHFV 563 +G+GS+G VY V + VAVK ++ A EF+ + + + H V Sbjct: 1043 LGQGSFGMVYEGVAKGIRDDPNEEIPVAVKTVNDRASFSDRREFLKEATTMKEFHCHHVV 1102 Query: 564 DLLGYCLEGDQRLLAYEFATMGSLHDILHG 653 LLG G L+ E +G L + L G Sbjct: 1103 KLLGVVSTGQPALVIMELMALGDLKNYLRG 1132
>CDKL1_MOUSE (Q8CEQ0) Cyclin-dependent kinase-like 1 (EC 2.7.11.22)| Length = 352 Score = 40.0 bits (92), Expect = 0.006 Identities = 28/93 (30%), Positives = 48/93 (51%), Gaps = 2/93 (2%) Frame = +3 Query: 372 EKTDDFGSKALVGEGSYGRVYYAV-LENGTHVAVKK-LDTSADPEPDNEFIAQVSVISRL 545 EK + G +GEGSYG V+ + G VA+K+ L+T DP + ++ ++ +L Sbjct: 2 EKYEKIGK---IGEGSYGVVFKCRNRDTGQIVAIKRFLETEDDPVIKKIALREIRMLKQL 58 Query: 546 KHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDI 644 KH + V+LL + L +E+ LH++ Sbjct: 59 KHPNLVNLLEVFRRKRRLHLVFEYCDHTVLHEL 91
>FGFR2_DROME (Q09147) Fibroblast growth factor receptor homolog 2 precursor (EC| 2.7.10.1) (Protein breathless) (dFGF-R1) Length = 1052 Score = 40.0 bits (92), Expect = 0.006 Identities = 27/92 (29%), Positives = 45/92 (48%), Gaps = 9/92 (9%) Frame = +3 Query: 399 ALVGEGSYGRVYYAVLEN--------GTHVAVKKLDTSADPEPDNEFIAQVSVISRL-KH 551 +++GEG++GRV A E T VAVK + + ++ V+ + KH Sbjct: 716 SILGEGAFGRVVMAEAEGLPRSPQLAETIVAVKMVKEEHTDTDMASLVREMEVMKMIGKH 775 Query: 552 EHFVDLLGYCLEGDQRLLAYEFATMGSLHDIL 647 + ++LLG C +G + E+A G+L D L Sbjct: 776 INIINLLGCCSQGGPLWVIVEYAPHGNLKDFL 807
>FGFR3_HUMAN (P22607) Fibroblast growth factor receptor 3 precursor (EC| 2.7.10.1) (FGFR-3) (CD333 antigen) Length = 806 Score = 40.0 bits (92), Expect = 0.006 Identities = 24/90 (26%), Positives = 46/90 (51%), Gaps = 9/90 (10%) Frame = +3 Query: 405 VGEGSYGRVYYAVL--------ENGTHVAVKKLDTSADPEPDNEFIAQVSVISRL-KHEH 557 +GEG +G+V A VAVK L A + ++ ++++ ++ + KH++ Sbjct: 478 LGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKN 537 Query: 558 FVDLLGYCLEGDQRLLAYEFATMGSLHDIL 647 ++LLG C +G + E+A G+L + L Sbjct: 538 IINLLGACTQGGPLYVLVEYAAKGNLREFL 567
>FGFR3_MOUSE (Q61851) Fibroblast growth factor receptor 3 precursor (EC| 2.7.10.1) (FGFR-3) (Heparin-binding growth factor receptor) Length = 801 Score = 40.0 bits (92), Expect = 0.006 Identities = 24/90 (26%), Positives = 46/90 (51%), Gaps = 9/90 (10%) Frame = +3 Query: 405 VGEGSYGRVYYAVL--------ENGTHVAVKKLDTSADPEPDNEFIAQVSVISRL-KHEH 557 +GEG +G+V A VAVK L A + ++ ++++ ++ + KH++ Sbjct: 472 LGEGCFGQVVMAEAIGIDKDRTAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKN 531 Query: 558 FVDLLGYCLEGDQRLLAYEFATMGSLHDIL 647 ++LLG C +G + E+A G+L + L Sbjct: 532 IINLLGACTQGGPLYVLVEYAAKGNLREFL 561
>CDK3_MOUSE (Q80YP0) Truncated cell division protein kinase 3 homolog| Length = 186 Score = 40.0 bits (92), Expect = 0.006 Identities = 28/84 (33%), Positives = 43/84 (51%), Gaps = 3/84 (3%) Frame = +3 Query: 381 DDFGSKALVGEGSYGRVYYAVLE-NGTHVAVKK--LDTSADPEPDNEFIAQVSVISRLKH 551 D F +GEG+YG VY A + G VA+KK LD A+ P + ++S++ LKH Sbjct: 2 DVFQKVEKIGEGTYGVVYKARNKVTGQLVALKKIRLDLEAEGVPSTA-VREISLLKELKH 60 Query: 552 EHFVDLLGYCLEGDQRLLAYEFAT 623 + + LL + + +EF T Sbjct: 61 PNIIKLLDVVHREKKLYMVFEFLT 84
>SSK22_YEAST (P25390) Serine/threonine-protein kinase SSK22 (EC 2.7.11.1) (MAP| kinase kinase kinase SSK22) (Suppressor of sensor kinase 22) Length = 1331 Score = 40.0 bits (92), Expect = 0.006 Identities = 28/91 (30%), Positives = 50/91 (54%), Gaps = 5/91 (5%) Frame = +3 Query: 396 KALVGEGSYGRVYYAV-LENGTHVAVKKL---DTSADPEPDNEFIAQVSVISRLKHEHFV 563 ++ +G G++G+VY A+ LENG +AVK++ DT+ + +++V+ L H + V Sbjct: 1037 RSFIGGGTFGQVYSAINLENGEILAVKEIKIHDTTTMKKIFPLIKEEMTVLEMLNHPNIV 1096 Query: 564 DLLGYCLEGDQRLLAYEFATMGSLHDIL-HG 653 G + D+ + E+ GSL +L HG Sbjct: 1097 QYYGVEVHRDKVNIFMEYCEGGSLASLLDHG 1127
>SRK4_SPOLA (P42690) Tyrosine-protein kinase isoform SRK4 (EC 2.7.10.2)| Length = 506 Score = 40.0 bits (92), Expect = 0.006 Identities = 23/83 (27%), Positives = 38/83 (45%) Frame = +3 Query: 405 VGEGSYGRVYYAVLENGTHVAVKKLDTSADPEPDNEFIAQVSVISRLKHEHFVDLLGYCL 584 +G G +G V+ + T VAVK L EF+ + S++ +L+H + L C Sbjct: 246 LGAGQFGEVWEGLWNGTTSVAVKTLKPGT--MSIEEFLEEASIMKQLRHPKLIQLYAVCT 303 Query: 585 EGDQRLLAYEFATMGSLHDILHG 653 + + + E GSL + L G Sbjct: 304 KEEPIYIVTELMKHGSLLEYLRG 326
>PAK7_MOUSE (Q8C015) Serine/threonine-protein kinase PAK 7 (EC 2.7.11.1)| (p21-activated kinase 7) (PAK-7) (p21-activated kinase 5) Length = 719 Score = 40.0 bits (92), Expect = 0.006 Identities = 28/82 (34%), Positives = 43/82 (52%), Gaps = 1/82 (1%) Frame = +3 Query: 405 VGEGSYGRVYYAVLEN-GTHVAVKKLDTSADPEPDNEFIAQVSVISRLKHEHFVDLLGYC 581 +GEGS G V A ++ G VAVKK+D + F +V ++ H++ VD+ Sbjct: 455 IGEGSTGIVCIATEKHTGKQVAVKKMDLRKQQRRELLF-NEVVIMRDYHHDNVVDMYNSY 513 Query: 582 LEGDQRLLAYEFATMGSLHDIL 647 L GD+ + EF G+L DI+ Sbjct: 514 LVGDELWVVMEFLEGGALTDIV 535
>PAK7_HUMAN (Q9P286) Serine/threonine-protein kinase PAK 7 (EC 2.7.11.1)| (p21-activated kinase 7) (PAK-7) (PAK-5) Length = 719 Score = 40.0 bits (92), Expect = 0.006 Identities = 28/82 (34%), Positives = 43/82 (52%), Gaps = 1/82 (1%) Frame = +3 Query: 405 VGEGSYGRVYYAVLEN-GTHVAVKKLDTSADPEPDNEFIAQVSVISRLKHEHFVDLLGYC 581 +GEGS G V A ++ G VAVKK+D + F +V ++ H++ VD+ Sbjct: 455 IGEGSTGIVCIATEKHTGKQVAVKKMDLRKQQRRELLF-NEVVIMRDYHHDNVVDMYSSY 513 Query: 582 LEGDQRLLAYEFATMGSLHDIL 647 L GD+ + EF G+L DI+ Sbjct: 514 LVGDELWVVMEFLEGGALTDIV 535
>SRC_RSVPA (P31693) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 522 Score = 40.0 bits (92), Expect = 0.006 Identities = 26/85 (30%), Positives = 44/85 (51%), Gaps = 2/85 (2%) Frame = +3 Query: 405 VGEGSYGRVYYAVLENGTHVAVKKLDT-SADPEPDNEFIAQVSVISRLKHEHFVDLLGYC 581 +G+G +G V+ T VA+K L + PE F+ + V+ +L+HE V L Y Sbjct: 269 LGQGYFGEVWMGTWNGTTRVAIKTLKPGTMSPE---AFLQEAQVMKKLRHEKLVQL--YA 323 Query: 582 LEGDQRL-LAYEFATMGSLHDILHG 653 + ++ + + E+ + GSL D L G Sbjct: 324 MVSEEPIYIVIEYMSKGSLLDFLKG 348
>KPSH2_HUMAN (Q96QS6) Serine/threonine-protein kinase H2 (EC 2.7.11.1) (PSK-H2)| Length = 385 Score = 40.0 bits (92), Expect = 0.006 Identities = 25/84 (29%), Positives = 40/84 (47%) Frame = +3 Query: 396 KALVGEGSYGRVYYAVLENGTHVAVKKLDTSADPEPDNEFIAQVSVISRLKHEHFVDLLG 575 KAL+G GS+ RV + K+ + + E ++++SV+ R+ H + V L+ Sbjct: 66 KALIGTGSFSRVVRVEQKTTKKPFAIKVMETREREGREACVSELSVLRRVSHRYIVQLME 125 Query: 576 YCLEGDQRLLAYEFATMGSLHDIL 647 DQ + E AT G L D L Sbjct: 126 IFETEDQVYMVMELATGGELFDRL 149
>CDKL1_HUMAN (Q00532) Cyclin-dependent kinase-like 1 (EC 2.7.11.22)| (Serine/threonine-protein kinase KKIALRE) (Protein kinase p42 KKIALRE) Length = 357 Score = 39.7 bits (91), Expect = 0.008 Identities = 28/93 (30%), Positives = 48/93 (51%), Gaps = 2/93 (2%) Frame = +3 Query: 372 EKTDDFGSKALVGEGSYGRVYYAV-LENGTHVAVKK-LDTSADPEPDNEFIAQVSVISRL 545 EK + G +GEGSYG V+ + G VA+KK L++ DP + ++ ++ +L Sbjct: 2 EKYEKIGK---IGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQL 58 Query: 546 KHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDI 644 KH + V+LL + L +E+ LH++ Sbjct: 59 KHPNLVNLLEVFRRKRRLHLVFEYCDHTVLHEL 91
>SRC_HUMAN (P12931) Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2)| (p60-Src) (c-Src) (pp60c-src) Length = 535 Score = 39.7 bits (91), Expect = 0.008 Identities = 26/84 (30%), Positives = 41/84 (48%), Gaps = 1/84 (1%) Frame = +3 Query: 405 VGEGSYGRVYYAVLENGTHVAVKKLDT-SADPEPDNEFIAQVSVISRLKHEHFVDLLGYC 581 +G+G +G V+ T VA+K L + PE F+ + V+ +L+HE V L Sbjct: 275 LGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPE---AFLQEAQVMKKLRHEKLVQLYAVV 331 Query: 582 LEGDQRLLAYEFATMGSLHDILHG 653 E + + E+ + GSL D L G Sbjct: 332 SE-EPIYIVTEYMSKGSLLDFLKG 354
>TNIK_MOUSE (P83510) Traf2 and NCK-interacting kinase (EC 2.7.11.1) (Fragments)| Length = 916 Score = 39.7 bits (91), Expect = 0.008 Identities = 29/114 (25%), Positives = 53/114 (46%), Gaps = 8/114 (7%) Frame = +3 Query: 330 PSIQVPELSFDELKEKTDDFGSKALVGEGSYGRVYYA-VLENGTHVAVKKLDTSADPEPD 506 P+ + E+ L++ F LVG G+YG+VY ++ G A+K +D + D E Sbjct: 6 PARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTGDEE-- 63 Query: 507 NEFIAQVSVISRLK-HEHFVDLLGYCLE------GDQRLLAYEFATMGSLHDIL 647 E +++++ + H + G ++ DQ L EF GS+ D++ Sbjct: 64 EEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLI 117
>FYN_MOUSE (P39688) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 533 Score = 39.7 bits (91), Expect = 0.008 Identities = 33/128 (25%), Positives = 54/128 (42%), Gaps = 1/128 (0%) Frame = +3 Query: 267 HSPERANGNGFTQIGDQGKAPPSIQVPELSFDELKEKTDDFGSKALVGEGSYGRVYYAVL 446 H E+A+G F P Q L+ D + D + +G+G + V+ Sbjct: 229 HYSEKADGLCFNLTVVSSSCTP--QTSGLAKDAWEVARDSLFLEKKLGQGCFAEVWLGTW 286 Query: 447 ENGTHVAVKKLDT-SADPEPDNEFIAQVSVISRLKHEHFVDLLGYCLEGDQRLLAYEFAT 623 T VA+K L + PE F+ + ++ +LKH+ V L E + + E+ + Sbjct: 287 NGNTKVAIKTLKPGTMSPE---SFLEEAQIMKKLKHDKLVQLYAVVSE-EPIYIVTEYMS 342 Query: 624 MGSLHDIL 647 GSL D L Sbjct: 343 KGSLLDFL 350
>FGFR2_XENLA (Q03364) Fibroblast growth factor receptor 2 precursor (EC| 2.7.10.1) (FGFR-2) Length = 813 Score = 39.7 bits (91), Expect = 0.008 Identities = 24/90 (26%), Positives = 46/90 (51%), Gaps = 9/90 (10%) Frame = +3 Query: 405 VGEGSYGRVYYAVL--------ENGTHVAVKKLDTSADPEPDNEFIAQVSVISRL-KHEH 557 +GEG +G+V A + VAVK L +A + + ++++ ++ + KH++ Sbjct: 477 LGEGCFGQVVMAEALGIDKERPKESVTVAVKMLKDNATEKDLADLVSEMEMMKMIGKHKN 536 Query: 558 FVDLLGYCLEGDQRLLAYEFATMGSLHDIL 647 ++LLG C +G + E+A G+L L Sbjct: 537 IINLLGACTQGGTLYVIVEYAAKGNLRQYL 566
>CDC2_HUMAN (P06493) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 39.7 bits (91), Expect = 0.008 Identities = 24/84 (28%), Positives = 45/84 (53%), Gaps = 2/84 (2%) Frame = +3 Query: 381 DDFGSKALVGEGSYGRVYYAVLEN-GTHVAVKKLDTSADPEP-DNEFIAQVSVISRLKHE 554 +D+ +GEG+YG VY + G VA+KK+ ++ E + I ++S++ L+H Sbjct: 2 EDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHP 61 Query: 555 HFVDLLGYCLEGDQRLLAYEFATM 626 + V L ++ + L +EF +M Sbjct: 62 NIVSLQDVLMQDSRLYLIFEFLSM 85
>CDC2_BOVIN (P48734) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 39.7 bits (91), Expect = 0.008 Identities = 24/84 (28%), Positives = 45/84 (53%), Gaps = 2/84 (2%) Frame = +3 Query: 381 DDFGSKALVGEGSYGRVYYAVLEN-GTHVAVKKLDTSADPEP-DNEFIAQVSVISRLKHE 554 +D+ +GEG+YG VY + G VA+KK+ ++ E + I ++S++ L+H Sbjct: 2 EDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHP 61 Query: 555 HFVDLLGYCLEGDQRLLAYEFATM 626 + V L ++ + L +EF +M Sbjct: 62 NIVSLQDVLMQDSRLYLIFEFLSM 85
>CSK_RAT (P32577) Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase)| Length = 450 Score = 39.7 bits (91), Expect = 0.008 Identities = 28/82 (34%), Positives = 43/82 (52%), Gaps = 1/82 (1%) Frame = +3 Query: 405 VGEGSYGRVYYAVLENGTHVAVKKLDTSADPEPDNEFIAQVSVISRLKHEHFVDLLGYCL 584 +G+G +G V G VAVK + A + F+A+ SV+++L+H + V LLG + Sbjct: 201 IGKGEFGDVMLGDYR-GNKVAVKCIKNDATAQA---FLAEASVMTQLRHSNLVQLLGVIV 256 Query: 585 EGDQRL-LAYEFATMGSLHDIL 647 E L + E+ GSL D L Sbjct: 257 EEKGGLYIVTEYMAKGSLVDYL 278
>CSK_MOUSE (P41241) Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase)| (Protein-tyrosine kinase MPK-2) (p50CSK) Length = 450 Score = 39.7 bits (91), Expect = 0.008 Identities = 28/82 (34%), Positives = 43/82 (52%), Gaps = 1/82 (1%) Frame = +3 Query: 405 VGEGSYGRVYYAVLENGTHVAVKKLDTSADPEPDNEFIAQVSVISRLKHEHFVDLLGYCL 584 +G+G +G V G VAVK + A + F+A+ SV+++L+H + V LLG + Sbjct: 201 IGKGEFGDVMLGDYR-GNKVAVKCIKNDATAQA---FLAEASVMTQLRHSNLVQLLGVIV 256 Query: 585 EGDQRL-LAYEFATMGSLHDIL 647 E L + E+ GSL D L Sbjct: 257 EEKGGLYIVTEYMAKGSLVDYL 278
>CSK_HUMAN (P41240) Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase)| (Protein-tyrosine kinase CYL) Length = 450 Score = 39.7 bits (91), Expect = 0.008 Identities = 28/82 (34%), Positives = 43/82 (52%), Gaps = 1/82 (1%) Frame = +3 Query: 405 VGEGSYGRVYYAVLENGTHVAVKKLDTSADPEPDNEFIAQVSVISRLKHEHFVDLLGYCL 584 +G+G +G V G VAVK + A + F+A+ SV+++L+H + V LLG + Sbjct: 201 IGKGEFGDVMLGDYR-GNKVAVKCIKNDATAQA---FLAEASVMTQLRHSNLVQLLGVIV 256 Query: 585 EGDQRL-LAYEFATMGSLHDIL 647 E L + E+ GSL D L Sbjct: 257 EEKGGLYIVTEYMAKGSLVDYL 278
>TNIK_HUMAN (Q9UKE5) TRAF2 and NCK-interacting kinase (EC 2.7.11.1)| Length = 1360 Score = 39.7 bits (91), Expect = 0.008 Identities = 29/114 (25%), Positives = 53/114 (46%), Gaps = 8/114 (7%) Frame = +3 Query: 330 PSIQVPELSFDELKEKTDDFGSKALVGEGSYGRVYYA-VLENGTHVAVKKLDTSADPEPD 506 P+ + E+ L++ F LVG G+YG+VY ++ G A+K +D + D E Sbjct: 6 PARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTGDEE-- 63 Query: 507 NEFIAQVSVISRLK-HEHFVDLLGYCLE------GDQRLLAYEFATMGSLHDIL 647 E +++++ + H + G ++ DQ L EF GS+ D++ Sbjct: 64 EEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLI 117
>TESK1_MOUSE (O70146) Dual specificity testis-specific protein kinase 1 (EC| 2.7.12.1) (Testicular protein kinase 1) Length = 627 Score = 39.7 bits (91), Expect = 0.008 Identities = 27/113 (23%), Positives = 47/113 (41%) Frame = +3 Query: 309 GDQGKAPPSIQVPELSFDELKEKTDDFGSKALVGEGSYGRVYYAVLENGTHVAVKKLDTS 488 G G+ PS S + DDF +G G + VY V V K++ Sbjct: 26 GGPGRGRPSSYRALRSAVSSLARVDDFDCAEKIGAGFFSEVYKVRHRQSGQVMVLKMNKL 85 Query: 489 ADPEPDNEFIAQVSVISRLKHEHFVDLLGYCLEGDQRLLAYEFATMGSLHDIL 647 P + + +V +++RL+H + + +G C+ Q E+ G+L +L Sbjct: 86 --PSNRSNTLREVQLMNRLRHPNILRFMGVCVHQGQLHALTEYMNGGTLEQLL 136
>SRC_RSVSA (P00524) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 39.7 bits (91), Expect = 0.008 Identities = 26/84 (30%), Positives = 41/84 (48%), Gaps = 1/84 (1%) Frame = +3 Query: 405 VGEGSYGRVYYAVLENGTHVAVKKLDT-SADPEPDNEFIAQVSVISRLKHEHFVDLLGYC 581 +G+G +G V+ T VA+K L + PE F+ + V+ +L+HE V L Sbjct: 272 LGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPE---AFLQEAQVMKKLRHEKLVQLYAVV 328 Query: 582 LEGDQRLLAYEFATMGSLHDILHG 653 E + + E+ + GSL D L G Sbjct: 329 SE-EPIYIVTEYMSKGSLLDFLKG 351
>SRC_AVIST (P14085) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 556 Score = 39.7 bits (91), Expect = 0.008 Identities = 26/84 (30%), Positives = 41/84 (48%), Gaps = 1/84 (1%) Frame = +3 Query: 405 VGEGSYGRVYYAVLENGTHVAVKKLDT-SADPEPDNEFIAQVSVISRLKHEHFVDLLGYC 581 +G+G +G V+ T VA+K L + PE F+ + V+ +L+HE V L Sbjct: 272 LGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPE---AFLQEAQVMKKLRHEKLVQLYAVV 328 Query: 582 LEGDQRLLAYEFATMGSLHDILHG 653 E + + E+ + GSL D L G Sbjct: 329 SE-EPIYIVTEYMSKGSLLDFLKG 351
>SRC_AVISR (P00525) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 39.7 bits (91), Expect = 0.008 Identities = 26/84 (30%), Positives = 41/84 (48%), Gaps = 1/84 (1%) Frame = +3 Query: 405 VGEGSYGRVYYAVLENGTHVAVKKLDT-SADPEPDNEFIAQVSVISRLKHEHFVDLLGYC 581 +G+G +G V+ T VA+K L + PE F+ + V+ +L+HE V L Sbjct: 272 LGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPE---AFLQEAQVMKKLRHEKLVQLYAVV 328 Query: 582 LEGDQRLLAYEFATMGSLHDILHG 653 E + + E+ + GSL D L G Sbjct: 329 SE-EPIYIVTEYMSKGSLLDFLKG 351
>FGFR1_XENLA (P22182) Fibroblast growth factor receptor 1 precursor (EC| 2.7.10.1) (FGFR-1) Length = 812 Score = 39.7 bits (91), Expect = 0.008 Identities = 24/90 (26%), Positives = 47/90 (52%), Gaps = 9/90 (10%) Frame = +3 Query: 405 VGEGSYGRVYYAVL--------ENGTHVAVKKLDTSADPEPDNEFIAQVSVISRL-KHEH 557 +GEG +G+V A T VAVK L + A + ++ I+++ ++ + KH++ Sbjct: 478 LGEGCFGQVVMAEAIGLDKEKPNKVTKVAVKMLKSDASEKDLSDLISEMEMMKMIGKHKN 537 Query: 558 FVDLLGYCLEGDQRLLAYEFATMGSLHDIL 647 ++LLG C + + E+ + G+L + L Sbjct: 538 IINLLGACTQDGPLYVIVEYTSKGNLREYL 567 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 88,095,003 Number of Sequences: 219361 Number of extensions: 1773501 Number of successful extensions: 5812 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 5500 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5677 length of database: 80,573,946 effective HSP length: 108 effective length of database: 56,882,958 effective search space used: 6200242422 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
