ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | basd12k05 |
|---|---|
| Clone Library Name | barley_pub |
>MPK3_ARATH (Q39023) Mitogen-activated protein kinase homolog 3 (EC 2.7.11.24)| (MAP kinase 3) (AtMPK3) Length = 370 Score = 209 bits (531), Expect = 6e-54 Identities = 101/168 (60%), Positives = 127/168 (75%), Gaps = 1/168 (0%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANA 202 +Y+ ELM++DLHQ+IR+N L+ EH Q+FLYQLLR LKYIH AN+ HRDLKP N+L NA Sbjct: 115 VYISTELMDTDLHQIIRSNQSLSEEHCQYFLYQLLRGLKYIHSANIIHRDLKPSNLLLNA 174 Query: 203 DCKLKICDFGLAR-VSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCI 379 +C LKICDFGLAR S ND F T+YV TRWYRAPEL + S YT AID+WS+GCI Sbjct: 175 NCDLKICDFGLARPTSEND-----FMTEYVVTRWYRAPELLLN-SSDYTAAIDVWSVGCI 228 Query: 380 FAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYLK 523 F EL+ +PLFPGK+ VHQ+ ++T+LLGTP+ L NE A+RY++ Sbjct: 229 FMELMNRKPLFPGKDHVHQMRLLTELLGTPTESDLGFTHNEDAKRYIR 276
>MPK5_ARATH (Q39025) Mitogen-activated protein kinase homolog 5 (EC 2.7.11.24)| (MAP kinase 5) (AtMPK5) Length = 376 Score = 208 bits (529), Expect = 1e-53 Identities = 97/167 (58%), Positives = 128/167 (76%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANA 202 +Y+VFELM++DLHQ+IR+N L +H Q+FLYQ+LR LKYIH ANV HRDLKP N+L N+ Sbjct: 120 VYIVFELMDTDLHQIIRSNQSLNDDHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNS 179 Query: 203 DCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIF 382 +C LKI DFGLAR + + T+YV TRWYRAPEL + S+YT AID+WS+GCIF Sbjct: 180 NCDLKITDFGLARTT----SETEYMTEYVVTRWYRAPELLLN-SSEYTSAIDVWSVGCIF 234 Query: 383 AELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYLK 523 AE++T PLFPGK+ VHQL +IT+L+G+P +L +R+ AR+Y+K Sbjct: 235 AEIMTREPLFPGKDYVHQLKLITELIGSPDGASLEFLRSANARKYVK 281
>MPK6_ARATH (Q39026) Mitogen-activated protein kinase homolog 6 (EC 2.7.11.24)| (MAP kinase 6) (AtMPK6) Length = 395 Score = 207 bits (527), Expect = 2e-53 Identities = 99/167 (59%), Positives = 129/167 (77%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANA 202 +Y+ +ELM++DLHQ+IR+N L+ EH Q+FLYQ+LR LKYIH ANV HRDLKP N+L NA Sbjct: 140 VYIAYELMDTDLHQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNA 199 Query: 203 DCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIF 382 +C LKICDFGLARV+ + F T+YV TRWYRAPEL + S YT AID+WS+GCIF Sbjct: 200 NCDLKICDFGLARVT----SESDFMTEYVVTRWYRAPELLLN-SSDYTAAIDVWSVGCIF 254 Query: 383 AELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYLK 523 EL+ +PLFPG++ VHQL ++ +L+GTPS E L + NE A+RY++ Sbjct: 255 MELMDRKPLFPGRDHVHQLRLLMELIGTPSEEELEFL-NENAKRYIR 300
>MPK4_ARATH (Q39024) Mitogen-activated protein kinase homolog 4 (EC 2.7.11.24)| (MAP kinase 4) (AtMPK4) Length = 376 Score = 206 bits (525), Expect = 3e-53 Identities = 98/171 (57%), Positives = 127/171 (74%) Frame = +2 Query: 11 NSKXIYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNI 190 N +Y+V+ELM++DLHQ+IR+N LT +H +FFLYQLLR LKY+H ANV HRDLKP N+ Sbjct: 116 NFNDVYIVYELMDTDLHQIIRSNQPLTDDHCRFFLYQLLRGLKYVHSANVLHRDLKPSNL 175 Query: 191 LANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSI 370 L NA+C LK+ DFGLAR F T+YV TRWYRAPEL + S+YT AIDIWS+ Sbjct: 176 LLNANCDLKLGDFGLARTK----SETDFMTEYVVTRWYRAPELLLN-CSEYTAAIDIWSV 230 Query: 371 GCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYLK 523 GCI E +T PLFPGK+ VHQL +IT+L+G+P +L +R++ ARRY++ Sbjct: 231 GCILGETMTREPLFPGKDYVHQLRLITELIGSPDDSSLGFLRSDNARRYVR 281
>MMK1_MEDSA (Q07176) Mitogen-activated protein kinase homolog MMK1 (EC| 2.7.11.24) (MAP kinase MSK7) (MAP kinase ERK1) Length = 387 Score = 206 bits (523), Expect = 5e-53 Identities = 98/167 (58%), Positives = 128/167 (76%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANA 202 +Y+ +ELM++DLHQ+IR+N L+ EH Q+FLYQ+LR LKYIH ANV HRDLKP N+L NA Sbjct: 132 VYIAYELMDTDLHQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNA 191 Query: 203 DCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIF 382 +C LKICDFGLARV+ F T+YV TRWYRAPEL + S YT AID+WS+GCIF Sbjct: 192 NCDLKICDFGLARVT----SETDFMTEYVVTRWYRAPELLLN-SSDYTAAIDVWSVGCIF 246 Query: 383 AELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYLK 523 EL+ +PLFPG++ VHQL ++ +L+GTPS + L + NE A+RY++ Sbjct: 247 MELMDRKPLFPGRDHVHQLRLLMELIGTPSEDDLGFL-NENAKRYIR 292
>MAPK_PEA (Q06060) Mitogen-activated protein kinase homolog D5 (EC 2.7.11.24)| Length = 394 Score = 204 bits (520), Expect = 1e-52 Identities = 98/167 (58%), Positives = 127/167 (76%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANA 202 +Y+ +ELM++DLHQ+IR+N L+ EH Q+FLYQ+LR LKYIH ANV HRDLKP N+L NA Sbjct: 139 VYIAYELMDTDLHQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNA 198 Query: 203 DCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIF 382 +C LKICDFGLARV+ F T+YV TRWYRAPEL + S YT AID+WS+GCIF Sbjct: 199 NCDLKICDFGLARVT----SETDFMTEYVVTRWYRAPELLLN-SSDYTAAIDVWSVGCIF 253 Query: 383 AELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYLK 523 EL+ +PLFPG++ VHQL ++ +L+GTPS L + NE A+RY++ Sbjct: 254 MELMDRKPLFPGRDHVHQLRLLMELIGTPSEADLGFL-NENAKRYIR 299
>NTF4_TOBAC (Q40532) Mitogen-activated protein kinase homolog NTF4 (EC| 2.7.11.24) (P45) Length = 393 Score = 204 bits (519), Expect = 1e-52 Identities = 98/167 (58%), Positives = 126/167 (75%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANA 202 +Y+ +ELM++DLHQ+IR+N L+ EH Q+FLYQ+LR LKYIH ANV HRDLKP N+L NA Sbjct: 137 VYIAYELMDTDLHQIIRSNQGLSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNA 196 Query: 203 DCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIF 382 +C LKICDFGLARV+ F T+YV TRWYRAPEL + S YT AID+WS+GCIF Sbjct: 197 NCDLKICDFGLARVT----SETDFMTEYVVTRWYRAPELLLN-SSDYTAAIDVWSVGCIF 251 Query: 383 AELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYLK 523 EL+ +PLFPG++ VHQL ++ +L+GTP SE NE A+RY++ Sbjct: 252 MELMDRKPLFPGRDHVHQLRLLMELIGTP-SEAEMEFLNENAKRYIR 297
>ERK1_DICDI (P42525) Extracellular signal-regulated kinase 1 (EC 2.7.11.24)| (ERK1) (MAP kinase 1) Length = 415 Score = 202 bits (515), Expect = 4e-52 Identities = 96/167 (57%), Positives = 128/167 (76%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANA 202 +Y+V ELM++DLHQ+I + L+ +H Q+F+YQ+LR LK+IH ANV HRDLKP N+L N Sbjct: 108 VYIVSELMDTDLHQIITSPQPLSDDHCQYFVYQMLRGLKHIHSANVLHRDLKPSNLLINE 167 Query: 203 DCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIF 382 DC LKICD GLARV DA F T+YVATRWYRAPE+ S ++KYT AIDIWS+GCIF Sbjct: 168 DCLLKICDLGLARV--EDATHQGFMTEYVATRWYRAPEVILS-WNKYTKAIDIWSVGCIF 224 Query: 383 AELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYLK 523 AELL +PLF GK+ +HQ+ +I + +G+PS E + I NE+AR++++ Sbjct: 225 AELLGRKPLFQGKDYIHQITLIIETIGSPSEEDICNIANEQARQFIR 271
>MMK2_MEDSA (Q40353) Mitogen-activated protein kinase homolog MMK2 (EC| 2.7.11.24) Length = 371 Score = 202 bits (514), Expect = 6e-52 Identities = 95/171 (55%), Positives = 128/171 (74%) Frame = +2 Query: 11 NSKXIYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNI 190 N +Y+V ELM++DLHQ+IR+N +T +H ++F+YQLLR LKY+H ANV HRDLKP N+ Sbjct: 110 NFNHVYIVSELMDTDLHQIIRSNQPMTDDHCRYFVYQLLRGLKYVHSANVLHRDLKPSNL 169 Query: 191 LANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSI 370 L NA+C LKI DFGLAR + F T+YV TRWYRAPEL + S YT AIDIWS+ Sbjct: 170 LLNANCDLKIGDFGLARTT----SETDFMTEYVVTRWYRAPELLLN-CSDYTAAIDIWSV 224 Query: 371 GCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYLK 523 GCI E++T +PLFPG++ VHQL ++T+L+G+P +L +R+E ARRY++ Sbjct: 225 GCILGEIVTRQPLFPGRDYVHQLRLVTELIGSPDDASLGFLRSENARRYVR 275
>MAPK_FUSSO (Q00859) Mitogen-activated protein kinase (EC 2.7.11.24) (FsMAPK)| Length = 355 Score = 201 bits (511), Expect = 1e-51 Identities = 93/167 (55%), Positives = 129/167 (77%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANA 202 +Y++ ELME+D+H+ IR D L+ +H Q+F+YQ LRALK +H ANV HRDLKP N+L NA Sbjct: 99 VYLIQELMETDMHRAIRTQD-LSDDHCQYFIYQTLRALKAMHSANVLHRDLKPSNLLLNA 157 Query: 203 DCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIF 382 +C LK+CDFGLAR + + ++ F T+YVATRWYRAPE+ + F +YT AID+WS+GCI Sbjct: 158 NCDLKVCDFGLARSAASQEDNSGFMTEYVATRWYRAPEIMLT-FKEYTKAIDVWSVGCIL 216 Query: 383 AELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYLK 523 AE+L+G+PLFPGK+ HQL +I D+LGTP+ E I++ +AR Y++ Sbjct: 217 AEMLSGKPLFPGKDYHHQLTLILDVLGTPTMEDYYGIKSRRAREYIR 263
>MK07_HUMAN (Q13164) Mitogen-activated protein kinase 7 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 5) (ERK-5) (ERK4) (BMK1 kinase) Length = 815 Score = 201 bits (510), Expect = 2e-51 Identities = 98/173 (56%), Positives = 124/173 (71%), Gaps = 1/173 (0%) Frame = +2 Query: 8 GNSKXIYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKN 187 G K +YVV +LMESDLHQ+I ++ LT EH ++FLYQLLR LKY+H A V HRDLKP N Sbjct: 127 GEFKSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSN 186 Query: 188 ILANADCKLKICDFGLAR-VSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIW 364 +L N +C+LKI DFG+AR + + A F T+YVATRWYRAPEL S +YT AID+W Sbjct: 187 LLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLS-LHEYTQAIDLW 245 Query: 365 SIGCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYLK 523 S+GCIF E+L R LFPGKN VHQL +I +LGTPS + + E+ R Y++ Sbjct: 246 SVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQ 298
>SPM1_SCHPO (Q92398) Mitogen-activated protein kinase spm1 (EC 2.7.11.24) (MAP| kinase spm1) (MAP kinase pmk1) Length = 422 Score = 200 bits (508), Expect(2) = 2e-51 Identities = 99/172 (57%), Positives = 124/172 (72%), Gaps = 1/172 (0%) Frame = +2 Query: 11 NSKXIYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNI 190 N +Y+ ELME+DL+ +I++ LT H+Q F+YQ+L LKYIH ANV HRDLKP N+ Sbjct: 96 NFNEVYIYEELMEADLNAIIKSGQPLTDAHFQSFIYQILCGLKYIHSANVIHRDLKPGNL 155 Query: 191 LANADCKLKICDFGLAR-VSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWS 367 L NADC+LKICDFGLAR S N + F T+YVATRWYRAPE+ S FS Y ID+WS Sbjct: 156 LVNADCELKICDFGLARGCSENPEENPGFMTEYVATRWYRAPEIMLS-FSSYHKGIDVWS 214 Query: 368 IGCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYLK 523 +GCI AELL G PLF GK+ VHQL++I LGTP ETLS I + +A+ Y++ Sbjct: 215 VGCILAELLGGTPLFKGKDFVHQLNLILHQLGTPDEETLSHISSSRAQEYVR 266 Score = 22.3 bits (46), Expect(2) = 2e-51 Identities = 7/16 (43%), Positives = 10/16 (62%) Frame = +3 Query: 534 KKHPVPLTQKFPNADP 581 K+ P+P FP A+P Sbjct: 270 KQRPIPFETNFPKANP 285
>MK07_MOUSE (Q9WVS8) Mitogen-activated protein kinase 7 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 5) (ERK-5) (BMK1 kinase) Length = 806 Score = 199 bits (507), Expect = 4e-51 Identities = 97/173 (56%), Positives = 124/173 (71%), Gaps = 1/173 (0%) Frame = +2 Query: 8 GNSKXIYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKN 187 G + +YVV +LMESDLHQ+I ++ LT EH ++FLYQLLR LKY+H A V HRDLKP N Sbjct: 128 GEFRSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSN 187 Query: 188 ILANADCKLKICDFGLAR-VSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIW 364 +L N +C+LKI DFG+AR + + A F T+YVATRWYRAPEL S +YT AID+W Sbjct: 188 LLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLS-LHEYTQAIDLW 246 Query: 365 SIGCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYLK 523 S+GCIF E+L R LFPGKN VHQL +I +LGTPS + + E+ R Y++ Sbjct: 247 SVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQ 299
>NTF6_TOBAC (Q40531) Mitogen-activated protein kinase homolog NTF6 (EC| 2.7.11.24) (P43) Length = 371 Score = 199 bits (507), Expect = 4e-51 Identities = 95/167 (56%), Positives = 124/167 (74%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANA 202 +Y+V+ELM++DLHQ+IR++ LT +H Q+FLYQLLR LKY+H ANV HRDLKP N+L NA Sbjct: 115 VYIVYELMDTDLHQIIRSSQALTDDHCQYFLYQLLRGLKYVHSANVLHRDLKPSNLLLNA 174 Query: 203 DCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIF 382 +C LKICDFGLAR + A F T+YV TRWYRAPEL + ++YT AIDIWS+GCI Sbjct: 175 NCDLKICDFGLARTT----SEADFMTEYVVTRWYRAPELLLN-CTEYTAAIDIWSVGCIL 229 Query: 383 AELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYLK 523 EL+ PLFPG++ QL +I LLG+P L +R++ AR+Y+K Sbjct: 230 MELIKREPLFPGRDYAQQLGLIIALLGSPEDSDLGFLRSDNARKYVK 276
>MKC1_CANAL (P43068) Mitogen-activated protein kinase MKC1 (EC 2.7.11.24) (MAP| kinase MKC1) Length = 501 Score = 198 bits (504), Expect = 8e-51 Identities = 100/173 (57%), Positives = 126/173 (72%), Gaps = 1/173 (0%) Frame = +2 Query: 8 GNSKXIYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKN 187 G IY+ ELME D+HQ+IR+ L+ +HYQ F+YQ+L L +IH A+V HRDLKP N Sbjct: 120 GEFNEIYLYEELMECDMHQIIRSGQPLSDQHYQSFIYQVLCGLNFIHSADVLHRDLKPGN 179 Query: 188 ILANADCKLKICDFGLAR-VSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIW 364 +L NADC+LKICDFGLAR S N +A F T+YVATRWYRAPE+ S F+ YT AIDIW Sbjct: 180 LLVNADCELKICDFGLARGFSENPDENAGFMTEYVATRWYRAPEIMLS-FTNYTKAIDIW 238 Query: 365 SIGCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYLK 523 S+GCI AELL G+PLF GK+ V QL+ I +LGTP TL RI + +A+ Y++ Sbjct: 239 SVGCILAELLGGKPLFRGKDYVDQLNQILMILGTPPESTLQRIGSHRAQNYVR 291
>ERK1_CANAL (P28869) Extracellular signal-regulated kinase 1 (EC 2.7.11.24)| (ERK1) (MAP kinase 1) (MAPK 1) Length = 417 Score = 195 bits (495), Expect = 9e-50 Identities = 93/167 (55%), Positives = 129/167 (77%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANA 202 IY++ ELME+DLH+VIR + L+ +H Q+F+YQ LRALK +H ANV HRDLKP N+L N+ Sbjct: 144 IYLIQELMETDLHRVIRTQN-LSDDHIQYFIYQTLRALKAMHSANVLHRDLKPSNLLLNS 202 Query: 203 DCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIF 382 +C LKICDFGLAR + + F T+YVATRWYRAPE+ + F +YT AID+WS+GCI Sbjct: 203 NCDLKICDFGLARSIASQEDNYGFMTEYVATRWYRAPEIMLT-FQEYTTAIDVWSVGCIL 261 Query: 383 AELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYLK 523 AE+L+GRPLFPG++ +QL +I ++LGTP+ E I++++AR Y++ Sbjct: 262 AEMLSGRPLFPGRDYHNQLWLIMEVLGTPNMEDYYNIKSKRAREYIR 308
>SLT2_YEAST (Q00772) Mitogen-activated protein kinase SLT2/MPK1 (EC 2.7.11.24)| (MAP kinase MPK1) Length = 484 Score = 193 bits (491), Expect = 3e-49 Identities = 96/172 (55%), Positives = 123/172 (71%), Gaps = 1/172 (0%) Frame = +2 Query: 8 GNSKXIYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKN 187 G+ +Y+ ELME D+HQ+I++ LT HYQ F YQ+L LKYIH A+V HRDLKP N Sbjct: 99 GSINGLYLYEELMECDMHQIIKSGQPLTDAHYQSFTYQILCGLKYIHSADVLHRDLKPGN 158 Query: 188 ILANADCKLKICDFGLAR-VSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIW 364 +L NADC+LKICDFGLAR S N ++ F T+YVATRWYRAPE+ S + YT AID+W Sbjct: 159 LLVNADCQLKICDFGLARGYSENPVENSQFLTEYVATRWYRAPEIMLS-YQGYTKAIDVW 217 Query: 365 SIGCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYL 520 S GCI AE L G+P+F GK+ V+QL+ I +LGTP ETL RI ++ + Y+ Sbjct: 218 SAGCILAEFLGGKPIFKGKDYVNQLNQILQVLGTPPDETLRRIGSKNVQDYI 269
>CPK1_CRYNE (Q8NK05) Mitogen-activated protein kinase CPK1 (EC 2.7.11.24)| (Stress-activated protein kinase CPK1) Length = 366 Score = 191 bits (486), Expect = 1e-48 Identities = 92/172 (53%), Positives = 127/172 (73%), Gaps = 5/172 (2%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANA 202 +Y+V ELME+DLH+VIR+ + L+ +H Q+F+YQ LR LK +H A+V HRDLKP N+L NA Sbjct: 92 VYLVQELMETDLHRVIRSQE-LSDDHCQYFVYQTLRGLKALHSADVLHRDLKPSNLLLNA 150 Query: 203 DCKLKICDFGLARVSFNDAPSAI-----FWTDYVATRWYRAPELCGSFFSKYTPAIDIWS 367 +C LKICDFGLAR S P F T+YVATRWYRAPE+ S F +YT AID+WS Sbjct: 151 NCDLKICDFGLARSSAKPPPGTSDGGQGFMTEYVATRWYRAPEVMLS-FQEYTKAIDLWS 209 Query: 368 IGCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYLK 523 +GCI AE++ G+PLFPG++ HQL +I +LGTP+ + + I +++++ YL+ Sbjct: 210 VGCILAEMINGKPLFPGRDYHHQLSLILQVLGTPTMDDFNEITSQRSKDYLR 261
>NTF3_TOBAC (Q40517) Mitogen-activated protein kinase homolog NTF3 (EC| 2.7.11.24) (P43) Length = 372 Score = 191 bits (486), Expect = 1e-48 Identities = 91/169 (53%), Positives = 124/169 (73%) Frame = +2 Query: 17 KXIYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILA 196 K +Y+V+ELM++DLHQ+I+++ L+ +H Q+FL+QLLR LKY+H AN+ HRDLKP N+L Sbjct: 107 KDVYLVYELMDTDLHQIIKSSQTLSNDHCQYFLFQLLRGLKYLHSANILHRDLKPGNLLI 166 Query: 197 NADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGC 376 NA+C LKICDFGLAR S + F T+YV TRWYRAPEL Y +ID+WS+GC Sbjct: 167 NANCDLKICDFGLARTS---SGKDQFMTEYVVTRWYRAPELL-LCCDNYGTSIDVWSVGC 222 Query: 377 IFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYLK 523 IFAELL +P+FPG ++QL +I ++LG+ E + I N KAR+Y+K Sbjct: 223 IFAELLGRKPVFPGTECLNQLKLIINILGSQREEDIEFIDNPKARKYIK 271
>MPK2_ARATH (Q39022) Mitogen-activated protein kinase homolog 2 (EC 2.7.11.24)| (MAP kinase 2) (AtMPK2) Length = 376 Score = 191 bits (484), Expect = 2e-48 Identities = 91/169 (53%), Positives = 123/169 (72%) Frame = +2 Query: 17 KXIYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILA 196 K +Y+V+ELM++DLHQ+I+++ L+ +H Q+FL+QLLR LKYIH AN+ HRDLKP N+L Sbjct: 107 KDVYLVYELMDTDLHQIIKSSQVLSNDHCQYFLFQLLRGLKYIHSANILHRDLKPGNLLV 166 Query: 197 NADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGC 376 NA+C LKICDFGLAR S F T+YV TRWYRAPEL Y +ID+WS+GC Sbjct: 167 NANCDLKICDFGLARTSNTKGQ---FMTEYVVTRWYRAPELL-LCCDNYGTSIDVWSVGC 222 Query: 377 IFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYLK 523 IFAELL +P+FPG ++Q+ +I ++LG+ E L I N KA+RY++ Sbjct: 223 IFAELLGRKPVFPGTECLNQIKLIINILGSQREEDLEFIDNPKAKRYIE 271
>MK01_XENLA (P26696) Mitogen-activated protein kinase 1 (EC 2.7.11.24) (Myelin| xP42 protein kinase) (Myelin basic protein kinase) (MBP kinase) (M phase MAP kinase) Length = 361 Score = 189 bits (479), Expect(2) = 2e-48 Identities = 94/168 (55%), Positives = 123/168 (73%) Frame = +2 Query: 17 KXIYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILA 196 K +Y+V +LME+DL+++++ L+ +H +FLYQ+LR LKYIH ANV HRDLKP N+L Sbjct: 102 KDVYIVQDLMETDLYKLLKTQH-LSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLL 160 Query: 197 NADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGC 376 N C LKICDFGLARV+ D F T+YVATRWYRAPE+ + YT +IDIWS+GC Sbjct: 161 NTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLN-SKGYTKSIDIWSVGC 219 Query: 377 IFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYL 520 I AE+L+ RP+FPGK+ + QL+ I +LG+PS E L+ I N KAR YL Sbjct: 220 ILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYL 267 Score = 23.5 bits (49), Expect(2) = 2e-48 Identities = 9/15 (60%), Positives = 11/15 (73%) Frame = +3 Query: 537 KHPVPLTQKFPNADP 581 K+ VP + FPNADP Sbjct: 273 KNKVPWNRLFPNADP 287
>MK03_HUMAN (P27361) Mitogen-activated protein kinase 3 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 1) (ERK-1) (Insulin-stimulated MAP2 kinase) (MAP kinase 1) (MAPK 1) (p44-ERK1) (ERT2) (p44-MAPK) (Microtubule-associated protein 2 kinase) Length = 379 Score = 190 bits (482), Expect = 3e-48 Identities = 94/178 (52%), Positives = 128/178 (71%) Frame = +2 Query: 17 KXIYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILA 196 + +Y+V +LME+DL++++++ L+ +H +FLYQ+LR LKYIH ANV HRDLKP N+L Sbjct: 116 RDVYIVQDLMETDLYKLLKSQQ-LSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLI 174 Query: 197 NADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGC 376 N C LKICDFGLAR++ + F T+YVATRWYRAPE+ + YT +IDIWS+GC Sbjct: 175 NTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLN-SKGYTKSIDIWSVGC 233 Query: 377 IFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYLKLHAKKTSCA 550 I AE+L+ RP+FPGK+ + QL+ I +LG+PS E L+ I N KAR YL+ KT A Sbjct: 234 ILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVA 291
>MK03_RAT (P21708) Mitogen-activated protein kinase 3 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 1) (ERK-1) (Insulin-stimulated MAP2 kinase) (MAP kinase 1) (MAPK 1) (p44-ERK1) (ERT2) (p44-MAPK) (Microtubule-associated protein 2 kinase) (MNK1) Length = 380 Score = 190 bits (482), Expect = 3e-48 Identities = 94/178 (52%), Positives = 128/178 (71%) Frame = +2 Query: 17 KXIYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILA 196 + +Y+V +LME+DL++++++ L+ +H +FLYQ+LR LKYIH ANV HRDLKP N+L Sbjct: 117 RDVYIVQDLMETDLYKLLKSQQ-LSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLI 175 Query: 197 NADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGC 376 N C LKICDFGLAR++ + F T+YVATRWYRAPE+ + YT +IDIWS+GC Sbjct: 176 NTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLN-SKGYTKSIDIWSVGC 234 Query: 377 IFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYLKLHAKKTSCA 550 I AE+L+ RP+FPGK+ + QL+ I +LG+PS E L+ I N KAR YL+ KT A Sbjct: 235 ILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVA 292
>MK03_MOUSE (Q63844) Mitogen-activated protein kinase 3 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 1) (ERK-1) (Insulin-stimulated MAP2 kinase) (MAP kinase 1) (MAPK 1) (p44-ERK1) (ERT2) (p44-MAPK) (Microtubule-associated protein 2 kinase) (MNK1) Length = 380 Score = 190 bits (482), Expect = 3e-48 Identities = 94/178 (52%), Positives = 128/178 (71%) Frame = +2 Query: 17 KXIYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILA 196 + +Y+V +LME+DL++++++ L+ +H +FLYQ+LR LKYIH ANV HRDLKP N+L Sbjct: 117 RDVYIVQDLMETDLYKLLKSQQ-LSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLI 175 Query: 197 NADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGC 376 N C LKICDFGLAR++ + F T+YVATRWYRAPE+ + YT +IDIWS+GC Sbjct: 176 NTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLN-SKGYTKSIDIWSVGC 234 Query: 377 IFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYLKLHAKKTSCA 550 I AE+L+ RP+FPGK+ + QL+ I +LG+PS E L+ I N KAR YL+ KT A Sbjct: 235 ILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVA 292
>MPK1_ARATH (Q39021) Mitogen-activated protein kinase homolog 1 (EC 2.7.11.24)| (MAP kinase 1) (AtMPK1) Length = 370 Score = 189 bits (481), Expect = 4e-48 Identities = 91/169 (53%), Positives = 122/169 (72%) Frame = +2 Query: 17 KXIYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILA 196 K +Y+V+ELM++DLHQ+I+++ L+ +H Q+FL+QLLR LKYIH AN+ HRDLKP N+L Sbjct: 107 KDVYLVYELMDTDLHQIIKSSQVLSNDHCQYFLFQLLRGLKYIHSANILHRDLKPGNLLV 166 Query: 197 NADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGC 376 NA+C LKICDFGLAR S F T+YV TRWYRAPEL Y +ID+WS+GC Sbjct: 167 NANCDLKICDFGLARASNTKGQ---FMTEYVVTRWYRAPELL-LCCDNYGTSIDVWSVGC 222 Query: 377 IFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYLK 523 IFAELL +P+F G ++QL +I ++LG+ E L I N KA+RY++ Sbjct: 223 IFAELLGRKPIFQGTECLNQLKLIVNILGSQREEDLEFIDNPKAKRYIR 271
>MAPK_PETHY (Q40884) Mitogen-activated protein kinase homolog 1 (EC 2.7.11.24)| (PMEK1) Length = 384 Score = 189 bits (480), Expect = 5e-48 Identities = 89/169 (52%), Positives = 124/169 (73%) Frame = +2 Query: 17 KXIYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILA 196 K +Y+V+ELM++DLHQ+I+++ L+ +H Q+FL+QLLR LKY+H AN+ HRDLKP N+L Sbjct: 107 KDVYLVYELMDTDLHQIIKSSQTLSNDHCQYFLFQLLRGLKYLHSANILHRDLKPGNLLI 166 Query: 197 NADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGC 376 NA+C LKICDFGLAR S + F T+YV TRWYRAPEL Y +ID+WS+GC Sbjct: 167 NANCDLKICDFGLARTS---SGKDQFMTEYVVTRWYRAPELL-LCCDNYGTSIDVWSVGC 222 Query: 377 IFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYLK 523 IFA++L +P+FPG ++QL +I ++LG+ E + I N KAR+Y+K Sbjct: 223 IFADVLGRKPVFPGTECLNQLKLIINILGSQREEDIEFIDNPKARKYIK 271
>MK01_HUMAN (P28482) Mitogen-activated protein kinase 1 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 2) (ERK-2) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2) (p42-MAPK) (ERT1) Length = 359 Score = 189 bits (479), Expect = 7e-48 Identities = 94/168 (55%), Positives = 123/168 (73%) Frame = +2 Query: 17 KXIYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILA 196 K +Y+V +LME+DL+++++ L+ +H +FLYQ+LR LKYIH ANV HRDLKP N+L Sbjct: 98 KDVYIVQDLMETDLYKLLKTQH-LSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLL 156 Query: 197 NADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGC 376 N C LKICDFGLARV+ D F T+YVATRWYRAPE+ + YT +IDIWS+GC Sbjct: 157 NTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLN-SKGYTKSIDIWSVGC 215 Query: 377 IFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYL 520 I AE+L+ RP+FPGK+ + QL+ I +LG+PS E L+ I N KAR YL Sbjct: 216 ILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYL 263
>MK01_BOVIN (P46196) Mitogen-activated protein kinase 1 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 2) (ERK-2) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2) (p42-MAPK) (ERT1) Length = 359 Score = 189 bits (479), Expect = 7e-48 Identities = 94/168 (55%), Positives = 123/168 (73%) Frame = +2 Query: 17 KXIYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILA 196 K +Y+V +LME+DL+++++ L+ +H +FLYQ+LR LKYIH ANV HRDLKP N+L Sbjct: 98 KDVYIVQDLMETDLYKLLKTQH-LSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLL 156 Query: 197 NADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGC 376 N C LKICDFGLARV+ D F T+YVATRWYRAPE+ + YT +IDIWS+GC Sbjct: 157 NTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLN-SKGYTKSIDIWSVGC 215 Query: 377 IFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYL 520 I AE+L+ RP+FPGK+ + QL+ I +LG+PS E L+ I N KAR YL Sbjct: 216 ILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYL 263
>MK01_RAT (P63086) Mitogen-activated protein kinase 1 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 2) (ERK-2) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2) (p42-MAPK) (ERT1) Length = 357 Score = 189 bits (479), Expect = 7e-48 Identities = 94/168 (55%), Positives = 123/168 (73%) Frame = +2 Query: 17 KXIYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILA 196 K +Y+V +LME+DL+++++ L+ +H +FLYQ+LR LKYIH ANV HRDLKP N+L Sbjct: 96 KDVYIVQDLMETDLYKLLKTQH-LSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLL 154 Query: 197 NADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGC 376 N C LKICDFGLARV+ D F T+YVATRWYRAPE+ + YT +IDIWS+GC Sbjct: 155 NTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLN-SKGYTKSIDIWSVGC 213 Query: 377 IFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYL 520 I AE+L+ RP+FPGK+ + QL+ I +LG+PS E L+ I N KAR YL Sbjct: 214 ILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYL 261
>MK01_MOUSE (P63085) Mitogen-activated protein kinase 1 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 2) (ERK-2) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2) (p42-MAPK) (ERT1) Length = 357 Score = 189 bits (479), Expect = 7e-48 Identities = 94/168 (55%), Positives = 123/168 (73%) Frame = +2 Query: 17 KXIYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILA 196 K +Y+V +LME+DL+++++ L+ +H +FLYQ+LR LKYIH ANV HRDLKP N+L Sbjct: 96 KDVYIVQDLMETDLYKLLKTQH-LSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLL 154 Query: 197 NADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGC 376 N C LKICDFGLARV+ D F T+YVATRWYRAPE+ + YT +IDIWS+GC Sbjct: 155 NTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLN-SKGYTKSIDIWSVGC 213 Query: 377 IFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYL 520 I AE+L+ RP+FPGK+ + QL+ I +LG+PS E L+ I N KAR YL Sbjct: 214 ILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYL 261
>SPK1_SCHPO (P27638) Mitogen-activated protein kinase spk1 (EC 2.7.11.24) (MAP| kinase spk1) (MAPK) Length = 372 Score = 188 bits (477), Expect = 1e-47 Identities = 91/167 (54%), Positives = 126/167 (75%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANA 202 +Y+V ELME+DL++VIR+ L+ +H Q+F YQ+LRALK +H A V HRDLKP N+L NA Sbjct: 115 VYIVQELMETDLYRVIRSQP-LSDDHCQYFTYQILRALKAMHSAGVVHRDLKPSNLLLNA 173 Query: 203 DCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIF 382 +C LK+ DFGLAR + + F T+YVATRWYRAPE+ S F +Y+ AID+WS GCI Sbjct: 174 NCDLKVADFGLARSTTAQGGNPGFMTEYVATRWYRAPEIMLS-FREYSKAIDLWSTGCIL 232 Query: 383 AELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYLK 523 AE+L+ RPLFPGK+ Q+ +I ++LGTP+ + SRI++ +AR+Y+K Sbjct: 233 AEMLSARPLFPGKDYHSQITLILNILGTPTMDDFSRIKSARARKYIK 279
>MPK7_ARATH (Q39027) Mitogen-activated protein kinase homolog 7 (EC 2.7.11.24)| (MAP kinase 7) (AtMPK7) Length = 368 Score = 187 bits (475), Expect = 2e-47 Identities = 87/169 (51%), Positives = 123/169 (72%) Frame = +2 Query: 17 KXIYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILA 196 K +Y+V+ELM++DLHQ+I+++ L+ +H ++FL+QLLR LKY+H AN+ HRDLKP N+L Sbjct: 107 KDVYLVYELMDTDLHQIIKSSQSLSDDHCKYFLFQLLRGLKYLHSANILHRDLKPGNLLV 166 Query: 197 NADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGC 376 NA+C LKICDFGLAR S + F T+YV TRWYRAPEL Y +ID+WS+GC Sbjct: 167 NANCDLKICDFGLARTSQGNEQ---FMTEYVVTRWYRAPELL-LCCDNYGTSIDVWSVGC 222 Query: 377 IFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYLK 523 IFAE+L +P+FPG ++QL +I +++G+ + I N KARR++K Sbjct: 223 IFAEILGRKPIFPGTECLNQLKLIINVVGSQQESDIRFIDNPKARRFIK 271
>SUR1_CAEEL (P39745) Mitogen-activated protein kinase mpk-1 (EC 2.7.11.24) (MAP| kinase sur-1) Length = 444 Score = 185 bits (469), Expect = 9e-47 Identities = 92/168 (54%), Positives = 122/168 (72%) Frame = +2 Query: 17 KXIYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILA 196 K IY+V LME+DL+++++ L+ +H +FLYQ+LR LKYIH ANV HRDLKP N+L Sbjct: 170 KDIYIVQCLMETDLYKLLKTQK-LSNDHVCYFLYQILRGLKYIHSANVLHRDLKPSNLLL 228 Query: 197 NADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGC 376 N C LKICDFGLARV+ F T+YVATRWYRAPE+ + YT +ID+WS+GC Sbjct: 229 NTTCDLKICDFGLARVTDPQTDHTGFLTEYVATRWYRAPEIMLN-SKGYTKSIDVWSVGC 287 Query: 377 IFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYL 520 I AE+L+ RPLFPGK+ + QL++I ++G+PS+ L I N+KAR YL Sbjct: 288 ILAEMLSNRPLFPGKHYLDQLNLILAVVGSPSNADLQCIINDKARSYL 335
>ERKA_DROME (P40417) Mitogen-activated protein kinase ERK-A (EC 2.7.11.24)| (Extracellular-regulated kinase A) (Protein rolled) Length = 376 Score = 184 bits (466), Expect = 2e-46 Identities = 91/169 (53%), Positives = 123/169 (72%) Frame = +2 Query: 17 KXIYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILA 196 + +Y+V LME+DL+++++ L+ +H +FLYQ+LR LKYIH ANV HRDLKP N+L Sbjct: 112 RDVYIVQCLMETDLYKLLKTQR-LSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLL 170 Query: 197 NADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGC 376 N C LKICDFGLAR++ + F T+YVATRWYRAPE+ + YT +IDIWS+GC Sbjct: 171 NKTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLN-SKGYTKSIDIWSVGC 229 Query: 377 IFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYLK 523 I AE+L+ RP+FPGK+ + QL+ I +LG+PS + L I NEKAR YL+ Sbjct: 230 ILAEMLSNRPIFPGKHYLDQLNHILGVLGSPSRDDLECIINEKARNYLE 278
>KSS1_YEAST (P14681) Mitogen-activated protein kinase KSS1 (EC 2.7.11.24) (MAP| kinase KSS1) (Kinase suppressor of SST2) Length = 368 Score = 183 bits (464), Expect = 4e-46 Identities = 90/174 (51%), Positives = 129/174 (74%), Gaps = 8/174 (4%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRANDD----LTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNI 190 +Y+V ELME+DL +VI + L+ +H Q+F YQ+LRALK IH A V HRD+KP N+ Sbjct: 90 VYLVEELMETDLQKVINNQNSGFSTLSDDHVQYFTYQILRALKSIHSAQVIHRDIKPSNL 149 Query: 191 LANADCKLKICDFGLAR--VSFNDAPSAI--FWTDYVATRWYRAPELCGSFFSKYTPAID 358 L N++C LK+CDFGLAR S +D+ + F T+YVATRWYRAPE+ +F +YT A+D Sbjct: 150 LLNSNCDLKVCDFGLARCLASSSDSRETLVGFMTEYVATRWYRAPEIMLTF-QEYTTAMD 208 Query: 359 IWSIGCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYL 520 IWS GCI AE+++G+PLFPG++ HQL +I ++LGTPS E ++I++++A+ Y+ Sbjct: 209 IWSCGCILAEMVSGKPLFPGRDYHHQLWLILEVLGTPSFEDFNQIKSKRAKEYI 262
>MK14B_DROME (O61443) Mitogen-activated protein kinase 14B (EC 2.7.11.24) (MAP| kinase p38b) (D-p38b) Length = 365 Score = 181 bits (460), Expect = 1e-45 Identities = 90/167 (53%), Positives = 118/167 (70%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANA 202 +Y+V LM++DL+ +IR L+ +H QF +YQ+LR LKYIH A V HRDLKP NI N Sbjct: 105 VYMVTHLMDADLNNIIRTQK-LSDDHVQFLVYQILRGLKYIHSAGVIHRDLKPSNIAVNE 163 Query: 203 DCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIF 382 DC+L+I DFGLAR P+ T YVATRWYRAPE+ ++ Y DIWS+GCI Sbjct: 164 DCELRILDFGLAR------PAESEMTGYVATRWYRAPEIMLNWMH-YNQTADIWSVGCIM 216 Query: 383 AELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYLK 523 AELLTGR LFPG + +HQL++I ++LGTP+ E +SRI +E AR Y++ Sbjct: 217 AELLTGRTLFPGTDHIHQLNLIMEVLGTPADEFMSRISSESARNYIR 263
>MK14A_DROME (O62618) Mitogen-activated protein kinase 14A (EC 2.7.11.24) (MAP| kinase p38a) (p38 MAPK) (Dp38) (D-p38a) Length = 366 Score = 178 bits (451), Expect = 1e-44 Identities = 88/171 (51%), Positives = 120/171 (70%) Frame = +2 Query: 11 NSKXIYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNI 190 N + +Y+V LM++DL+ +IR L+ +H QF +YQ+LR LKYIH A V HRDLKP NI Sbjct: 102 NFQQVYLVTHLMDADLNNIIRMQH-LSDDHVQFLVYQILRGLKYIHSAGVIHRDLKPSNI 160 Query: 191 LANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSI 370 N DC+L+I DFGLAR + N+ T YVATRWYRAPE+ ++ Y +DIWS+ Sbjct: 161 AVNEDCELRILDFGLARPTENE------MTGYVATRWYRAPEIMLNWM-HYDQTVDIWSV 213 Query: 371 GCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYLK 523 GCI AEL+T R LFPG + +HQL++I ++LGTP +E L +I +E AR Y++ Sbjct: 214 GCIMAELITRRTLFPGTDHIHQLNLIMEMLGTPPAEFLKKISSESARSYIQ 264
>FUS3_YEAST (P16892) Mitogen-activated protein kinase FUS3 (EC 2.7.11.24) (MAP| kinase FUS3) Length = 353 Score = 173 bits (438), Expect = 4e-43 Identities = 88/179 (49%), Positives = 126/179 (70%), Gaps = 8/179 (4%) Frame = +2 Query: 11 NSKXIYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNI 190 N +Y++ ELM++DLH+VI + L+ +H Q+F+YQ LRA+K +HG+NV HRDLKP N+ Sbjct: 85 NFNEVYIIQELMQTDLHRVI-STQMLSDDHIQYFIYQTLRAVKVLHGSNVIHRDLKPSNL 143 Query: 191 LANADCKLKICDFGLARV-----SFNDAPSA--IFWTDYVATRWYRAPELCGSFFSKYTP 349 L N++C LK+CDFGLAR+ + N P+ T+YVATRWYRAPE+ + +KY+ Sbjct: 144 LINSNCDLKVCDFGLARIIDESAADNSEPTGQQSGMTEYVATRWYRAPEVMLT-SAKYSR 202 Query: 350 AIDIWSIGCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSET-LSRIRNEKARRYLK 523 A+D+WS GCI AEL RP+FPG++ HQL +I ++GTP S+ L I + +AR Y+K Sbjct: 203 AMDVWSCGCILAELFLRRPIFPGRDYRHQLLLIFGIIGTPHSDNDLRCIESPRAREYIK 261
>MK14_RAT (P70618) Mitogen-activated protein kinase 14 (EC 2.7.11.24)| (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (CRK1) Length = 359 Score = 173 bits (438), Expect = 4e-43 Identities = 85/167 (50%), Positives = 116/167 (69%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANA 202 +Y+V LM +DL+ +++ LT +H QF +YQ+LR LKYIH A++ HRDLKP N+ N Sbjct: 101 VYLVTHLMGADLNNIVKCQK-LTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNE 159 Query: 203 DCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIF 382 DC+LKI DFGLAR + ++ T YVATRWYRAPE+ ++ Y +DIWS+GCI Sbjct: 160 DCELKILDFGLARHTDDE------MTGYVATRWYRAPEIMLNWM-HYNQTVDIWSVGCIM 212 Query: 383 AELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYLK 523 AELLTGR LFPG + + QL +I L+GTP +E L +I +E AR Y++ Sbjct: 213 AELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKISSESARNYIQ 259
>MK14_MOUSE (P47811) Mitogen-activated protein kinase 14 (EC 2.7.11.24)| (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (CRK1) Length = 359 Score = 173 bits (438), Expect = 4e-43 Identities = 85/167 (50%), Positives = 116/167 (69%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANA 202 +Y+V LM +DL+ +++ LT +H QF +YQ+LR LKYIH A++ HRDLKP N+ N Sbjct: 101 VYLVTHLMGADLNNIVKCQK-LTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNE 159 Query: 203 DCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIF 382 DC+LKI DFGLAR + ++ T YVATRWYRAPE+ ++ Y +DIWS+GCI Sbjct: 160 DCELKILDFGLARHTDDE------MTGYVATRWYRAPEIMLNWM-HYNQTVDIWSVGCIM 212 Query: 383 AELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYLK 523 AELLTGR LFPG + + QL +I L+GTP +E L +I +E AR Y++ Sbjct: 213 AELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKISSESARNYIQ 259
>MK14_HUMAN (Q16539) Mitogen-activated protein kinase 14 (EC 2.7.11.24)| (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (Cytokine suppressive anti-inflammatory drug-binding protein) (CSAID-binding protein) (CSBP) (MAX-interacting prote Length = 359 Score = 173 bits (438), Expect = 4e-43 Identities = 85/167 (50%), Positives = 116/167 (69%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANA 202 +Y+V LM +DL+ +++ LT +H QF +YQ+LR LKYIH A++ HRDLKP N+ N Sbjct: 101 VYLVTHLMGADLNNIVKCQK-LTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNE 159 Query: 203 DCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIF 382 DC+LKI DFGLAR + ++ T YVATRWYRAPE+ ++ Y +DIWS+GCI Sbjct: 160 DCELKILDFGLARHTDDE------MTGYVATRWYRAPEIMLNWM-HYNQTVDIWSVGCIM 212 Query: 383 AELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYLK 523 AELLTGR LFPG + + QL +I L+GTP +E L +I +E AR Y++ Sbjct: 213 AELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKISSESARNYIQ 259
>MK14_CANFA (O02812) Mitogen-activated protein kinase 14 (EC 2.7.11.24)| (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) Length = 359 Score = 172 bits (435), Expect = 8e-43 Identities = 84/167 (50%), Positives = 116/167 (69%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANA 202 +Y+V LM +DL+ +++ LT +H QF +YQ+LR LKYIH A++ HRDLKP N+ N Sbjct: 101 VYLVTHLMGADLNNIVKCQK-LTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNE 159 Query: 203 DCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIF 382 DC+LKI DFGLAR + ++ T YVATRWYRAPE+ ++ Y +DIWS+GCI Sbjct: 160 DCELKILDFGLARHTDDE------MTGYVATRWYRAPEIMLNWM-HYNQTVDIWSVGCIM 212 Query: 383 AELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYLK 523 AELLTGR LFPG + + QL +I L+GTP ++ L +I +E AR Y++ Sbjct: 213 AELLTGRTLFPGTDHIDQLKLILRLVGTPGADLLKKISSESARNYIQ 259
>MK14_XENLA (P47812) Mitogen-activated protein kinase 14 (EC 2.7.11.24)| (Mitogen-activated Mitogen-activated protein kinase 2) (MAP kinase 2) (MPK2) Length = 361 Score = 171 bits (433), Expect = 1e-42 Identities = 85/167 (50%), Positives = 113/167 (67%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANA 202 +Y+V LM +DL+ +++ LT +H QF +YQ+LR LKYIH A + HRDLKP N+ N Sbjct: 103 VYLVTHLMGADLNNIVKCQK-LTDDHVQFLIYQILRGLKYIHSAGIIHRDLKPSNLAVNE 161 Query: 203 DCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIF 382 DC+LKI DFGLAR + + T YVATRWYRAPE+ ++ Y +DIWS+GCI Sbjct: 162 DCELKILDFGLARHTDEE------MTGYVATRWYRAPEIMLNWM-HYNQTVDIWSVGCIM 214 Query: 383 AELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYLK 523 AELLTGR LFPG + + QL +I L+GTP E L +I +E AR Y++ Sbjct: 215 AELLTGRTLFPGTDHIDQLKLILRLVGTPEPELLQKISSEAARNYIQ 261
>MK14B_BRARE (Q9DGE1) Mitogen-activated protein kinase 14b (EC 2.7.11.24)| (Mitogen-activated protein kinase p38b) (MAP kinase p38b) (zp38b) Length = 348 Score = 170 bits (431), Expect = 2e-42 Identities = 84/166 (50%), Positives = 116/166 (69%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANA 202 +Y+V LM +DL+ +++ LT +H QF +YQ+LRALKYIH A++ HRDLKP N+ N Sbjct: 103 VYLVTHLMGADLNNIVKCQK-LTDDHVQFLIYQILRALKYIHSADIIHRDLKPSNLAVNE 161 Query: 203 DCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIF 382 DC+LKI DFGLAR++ ++ T YVATRWYRAPE+ ++ Y +DIWS+GCI Sbjct: 162 DCELKILDFGLARLTDDE------MTGYVATRWYRAPEIMLNWM-HYNMTVDIWSVGCIM 214 Query: 383 AELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYL 520 AELLTGR LFPG + ++QL I L GTP + +SR+ + +AR Y+ Sbjct: 215 AELLTGRTLFPGTDHINQLQQIMRLTGTPPASLISRMPSHEARNYI 260
>HOG1_ASHGO (Q750A9) Mitogen-activated protein kinase HOG1 (EC 2.7.11.24) (MAP| kinase HOG1) Length = 447 Score = 170 bits (431), Expect = 2e-42 Identities = 85/166 (51%), Positives = 113/166 (68%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANA 202 IY V EL +DLH++++ L + Q+FLYQ+LR LKY+H A V HRDLKP NIL N Sbjct: 96 IYFVTELQGTDLHRLLQTRP-LEKQFLQYFLYQILRGLKYVHSAGVIHRDLKPSNILINE 154 Query: 203 DCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIF 382 +C LKICDFGLAR+ T YV+TR+YRAPE+ + + KY +DIWS GCIF Sbjct: 155 NCDLKICDFGLARIQDPQ------MTGYVSTRYYRAPEIMLT-WQKYNVEVDIWSAGCIF 207 Query: 383 AELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYL 520 AE++ G+PLFPGK+ VHQ IITDLLG+P + + I +E +++ Sbjct: 208 AEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLKFV 253
>HOG1_YEAST (P32485) Mitogen-activated protein kinase HOG1 (EC 2.7.11.24) (MAP| kinase HOG1) (Osmosensing protein HOG1) Length = 435 Score = 170 bits (431), Expect = 2e-42 Identities = 85/166 (51%), Positives = 114/166 (68%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANA 202 IY V EL +DLH++++ L + Q+FLYQ+LR LKY+H A V HRDLKP NIL N Sbjct: 96 IYFVTELQGTDLHRLLQTRP-LEKQFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINE 154 Query: 203 DCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIF 382 +C LKICDFGLAR+ T YV+TR+YRAPE+ + + KY +DIWS GCIF Sbjct: 155 NCDLKICDFGLARIQDPQ------MTGYVSTRYYRAPEIMLT-WQKYDVEVDIWSAGCIF 207 Query: 383 AELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYL 520 AE++ G+PLFPGK+ VHQ IITDLLG+P + ++ I +E +++ Sbjct: 208 AEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVINTICSENTLKFV 253
>STY1_SCHPO (Q09892) Mitogen-activated protein kinase sty1 (EC 2.7.11.24) (MAP| kinase sty1) (MAP kinase spc1) Length = 349 Score = 166 bits (421), Expect(2) = 5e-42 Identities = 83/167 (49%), Positives = 115/167 (68%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANA 202 IY V EL+ +DLH+++ + L + Q+FLYQ+LR LK++H A V HRDLKP NIL N Sbjct: 93 IYFVTELLGTDLHRLLTSRP-LETQFIQYFLYQILRGLKFVHSAGVIHRDLKPSNILINE 151 Query: 203 DCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIF 382 +C LKICDFGLAR+ T YV+TR+YRAPE+ + + KY +DIWS GCIF Sbjct: 152 NCDLKICDFGLARIQDPQ------MTGYVSTRYYRAPEIMLT-WQKYNVEVDIWSAGCIF 204 Query: 383 AELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYLK 523 AE++ G+PLFPG++ V+Q IIT+LLGTP E + I ++ R+++ Sbjct: 205 AEMIEGKPLFPGRDHVNQFSIITELLGTPPMEVIETICSKNTLRFVQ 251 Score = 24.3 bits (51), Expect(2) = 5e-42 Identities = 9/16 (56%), Positives = 11/16 (68%) Frame = +3 Query: 534 KKHPVPLTQKFPNADP 581 +K VP +KF NADP Sbjct: 255 QKEKVPFAEKFKNADP 270
>MK14B_CYPCA (Q9I958) Mitogen-activated protein kinase 14b (EC 2.7.11.24)| (Mitogen-activated protein kinase p38b) (MAP kinase p38b) (cp38b) Length = 361 Score = 169 bits (427), Expect = 7e-42 Identities = 83/166 (50%), Positives = 115/166 (69%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANA 202 +Y+V LM +DL+ +++ LT +H QF +YQ+LR LKYIH A++ HRDLKP N+ N Sbjct: 103 VYLVTHLMGADLNNIVKCQK-LTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNE 161 Query: 203 DCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIF 382 DC+LKI DFGLAR++ ++ T YVATRWYRAPE+ ++ Y +DIWS+GCI Sbjct: 162 DCELKILDFGLARLTDDE------MTGYVATRWYRAPEIMLNWM-HYNMTVDIWSVGCIM 214 Query: 383 AELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYL 520 AELLTGR LFPG + ++QL I L GTP + +SR+ + +AR Y+ Sbjct: 215 AELLTGRTLFPGTDHINQLQQIMRLTGTPPASLISRMPSHEARNYI 260
>NLK_MOUSE (O54949) Serine/threonine kinase NLK (EC 2.7.11.24) (Nemo-like| kinase) Length = 515 Score = 169 bits (427), Expect = 7e-42 Identities = 87/155 (56%), Positives = 113/155 (72%), Gaps = 1/155 (0%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANA 202 IYVV ELM+SDLH++I + L+++H + FLYQ+LR LKY+H A + HRD+KP N+L N+ Sbjct: 203 IYVVTELMQSDLHKIIVSPQPLSSDHVKVFLYQILRGLKYLHSAGILHRDIKPGNLLVNS 262 Query: 203 DCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPE-LCGSFFSKYTPAIDIWSIGCI 379 +C LKICDFGLARV + + T V T++YRAPE L GS Y+ AIDIWS+GCI Sbjct: 263 NCVLKICDFGLARV--EELDESRHMTQEVVTQYYRAPEILMGS--RHYSNAIDIWSVGCI 318 Query: 380 FAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETL 484 FAELL R LF ++ + QLD+ITDLLGTPS E + Sbjct: 319 FAELLGRRILFQAQSPIQQLDLITDLLGTPSLEAM 353
>NLK_HUMAN (Q9UBE8) Serine/threonine kinase NLK (EC 2.7.11.24) (Nemo-like| kinase) (LAK1 protein) Length = 515 Score = 169 bits (427), Expect = 7e-42 Identities = 87/155 (56%), Positives = 113/155 (72%), Gaps = 1/155 (0%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANA 202 IYVV ELM+SDLH++I + L+++H + FLYQ+LR LKY+H A + HRD+KP N+L N+ Sbjct: 203 IYVVTELMQSDLHKIIVSPQPLSSDHVKVFLYQILRGLKYLHSAGILHRDIKPGNLLVNS 262 Query: 203 DCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPE-LCGSFFSKYTPAIDIWSIGCI 379 +C LKICDFGLARV + + T V T++YRAPE L GS Y+ AIDIWS+GCI Sbjct: 263 NCVLKICDFGLARV--EELDESRHMTQEVVTQYYRAPEILMGS--RHYSNAIDIWSVGCI 318 Query: 380 FAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETL 484 FAELL R LF ++ + QLD+ITDLLGTPS E + Sbjct: 319 FAELLGRRILFQAQSPIQQLDLITDLLGTPSLEAM 353
>HOG1_ZYGRO (O93982) Mitogen-activated protein kinase HOG1 (EC 2.7.11.24) (MAP| kinase HOG1) Length = 380 Score = 169 bits (427), Expect = 7e-42 Identities = 84/166 (50%), Positives = 114/166 (68%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANA 202 IY V EL +DLH++++ L + Q+FLYQ+LR LKY+H A V HRDLKP NIL N Sbjct: 96 IYFVTELQGTDLHRLLQTRP-LEKQFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINE 154 Query: 203 DCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIF 382 +C LKICDFGLAR+ T YV+TR+YRAPE+ + + KY +DIWS GCIF Sbjct: 155 NCDLKICDFGLARIQDPQ------MTGYVSTRYYRAPEIMLT-WQKYDVEVDIWSAGCIF 207 Query: 383 AELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYL 520 +E++ G+PLFPGK+ VHQ IITDLLG+P + ++ I +E +++ Sbjct: 208 SEMIEGKPLFPGKDHVHQFSIITDLLGSPPRDVINTICSENTLKFV 253
>HOG1_CANGA (Q6FIU2) Mitogen-activated protein kinase HOG1 (EC 2.7.11.24) (MAP| kinase HOG1) Length = 447 Score = 168 bits (426), Expect = 9e-42 Identities = 85/166 (51%), Positives = 113/166 (68%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANA 202 IY V EL +DLH++++ L + Q+F YQ+LR LKY+H A V HRDLKP NIL N Sbjct: 96 IYFVTELQGTDLHRLLQTRP-LEKQFVQYFHYQILRGLKYVHSAGVVHRDLKPSNILINE 154 Query: 203 DCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIF 382 +C LKICDFGLAR+ T YV+TR+YRAPE+ ++ KY +DIWS GCIF Sbjct: 155 NCDLKICDFGLARIQDPQM------TGYVSTRYYRAPEIMLTW-QKYDVEVDIWSAGCIF 207 Query: 383 AELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYL 520 AE++ G+PLFPGK+ VHQ IITDLLG+P S+ + I +E +++ Sbjct: 208 AEMIEGKPLFPGKDHVHQFSIITDLLGSPPSDVIDTICSENTLKFV 253
>MK14A_BRARE (Q9DGE2) Mitogen-activated protein kinase 14a (EC 2.7.11.24)| (Mitogen-activated protein kinase p38a) (MAP kinase p38a) (zp38a) Length = 361 Score = 168 bits (425), Expect = 1e-41 Identities = 84/166 (50%), Positives = 114/166 (68%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANA 202 +Y+V LM +DL+ +++ LT +H QF +YQ+LR LKYIH A++ HRDLKP N+ N Sbjct: 103 VYLVTHLMGADLNNIVKCQK-LTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNE 161 Query: 203 DCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIF 382 DC+LKI DFGLAR + ++ T YVATRWYRAPE+ ++ Y +DIWS+GCI Sbjct: 162 DCELKILDFGLARHTDDE------MTGYVATRWYRAPEIMLNWM-HYNVTVDIWSVGCIM 214 Query: 383 AELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYL 520 AELLTGR LFPG + ++QL I L GTP S +SR+ + +AR Y+ Sbjct: 215 AELLTGRTLFPGTDHINQLQQIMRLTGTPPSSLISRMPSHEARTYI 260
>MK14A_CYPCA (Q90336) Mitogen-activated protein kinase 14a (EC 2.7.11.24)| (Mitogen-activated protein kinase p38a) (MAP kinase p38a) (cp38a) Length = 361 Score = 167 bits (422), Expect = 3e-41 Identities = 83/166 (50%), Positives = 114/166 (68%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANA 202 +Y+V LM +DL+ +++ LT +H QF +YQ+LR LKYIH A++ HRDLKP N+ N Sbjct: 103 VYLVTHLMGADLNNIVKCQK-LTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNE 161 Query: 203 DCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIF 382 DC+LKI DFGLAR + ++ T YVATRWYRAPE+ ++ Y +DIWS+GCI Sbjct: 162 DCELKILDFGLARHTDDE------MTGYVATRWYRAPEIMLNWM-HYNMTVDIWSVGCIM 214 Query: 383 AELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYL 520 AELLTGR LFPG + ++QL I L GTP + +SR+ + +AR Y+ Sbjct: 215 AELLTGRTLFPGTDHINQLQQIMRLTGTPPASLISRMPSHEARTYI 260
>PMK1_CAEEL (Q17446) Mitogen-activated protein kinase pmk-1 (EC 2.7.11.24) (p38| MAP kinase 1) (Stress-activated protein kinase pmk-1) Length = 377 Score = 167 bits (422), Expect = 3e-41 Identities = 87/176 (49%), Positives = 115/176 (65%), Gaps = 3/176 (1%) Frame = +2 Query: 23 IYVVFELMESDLHQVI---RANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNIL 193 +Y V LM +DL ++ R NDD H QF +YQ+LR LKYIH A++ HRDLKP NI Sbjct: 113 VYFVSMLMGADLSNILKIQRLNDD----HIQFLVYQILRGLKYIHSADIIHRDLKPSNIA 168 Query: 194 ANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIG 373 N DC+LKI DFGLAR + ++ T YVATRWYRAPE+ ++ YT +D+WS+G Sbjct: 169 VNEDCELKILDFGLARQTDSE------MTGYVATRWYRAPEIMLNWM-HYTQTVDVWSVG 221 Query: 374 CIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYLKLHAKKT 541 CI AEL+TG+ LFPG + + QL I + GTP E L +I +E+AR Y++ K T Sbjct: 222 CILAELITGKTLFPGSDHIDQLTRIMSVTGTPDEEFLKKISSEEARNYIRNLPKMT 277
>MK14_PANTR (Q95NE7) Mitogen-activated protein kinase 14 (EC 2.7.11.24)| (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (Stress-activated protein kinase 2a) Length = 359 Score = 166 bits (420), Expect = 5e-41 Identities = 82/167 (49%), Positives = 115/167 (68%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANA 202 +Y+V LM +DL+ +++ LT +H QF +YQ+LR LKYIH A++ HRDLKP N+ N Sbjct: 101 VYLVTHLMGADLNNIVKCQK-LTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNE 159 Query: 203 DCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIF 382 DC+LKI DFGLAR + ++ T YVATRWYRAPE+ ++ Y +DIWS+GCI Sbjct: 160 DCELKILDFGLARHTDDE------MTGYVATRWYRAPEIMLNWM-HYNQTVDIWSVGCIM 212 Query: 383 AELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYLK 523 AELLTGR LFPG + ++QL I L GTP + ++R+ + +AR Y++ Sbjct: 213 AELLTGRTLFPGTDHINQLQQIMRLTGTPPAYLINRMPSHEARNYIQ 259
>HOG1_CANAL (Q92207) Mitogen-activated protein kinase HOG1 (EC 2.7.11.24) (MAP| kinase HOG1) Length = 377 Score = 166 bits (419), Expect = 6e-41 Identities = 82/167 (49%), Positives = 114/167 (68%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANA 202 IY V EL +DLH+++ + L + Q+F YQ++R LKYIH A V HRDLKP NIL N Sbjct: 96 IYFVNELQGTDLHRLLNSRP-LEKQFIQYFTYQIMRGLKYIHSAGVIHRDLKPSNILINE 154 Query: 203 DCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIF 382 +C LKICDFGLAR+ T YV+TR+YRAPE+ + + KY +D+WS+GCI Sbjct: 155 NCDLKICDFGLARLQDPQ------MTGYVSTRYYRAPEIMLT-WQKYDTEVDLWSVGCIL 207 Query: 383 AELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYLK 523 AE++ G+PLFPGK+ VHQ IIT+LLG+P ++ + I +E R+++ Sbjct: 208 AEMIEGKPLFPGKDHVHQFSIITELLGSPPADVIDTICSENTLRFVQ 254
>MK11_MOUSE (Q9WUI1) Mitogen-activated protein kinase 11 (EC 2.7.11.24)| (Mitogen-activated protein kinase p38 beta) (MAP kinase p38 beta) (p38B) Length = 364 Score = 165 bits (418), Expect = 8e-41 Identities = 82/167 (49%), Positives = 113/167 (67%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANA 202 +Y+V LM +DL+ +++ L+ EH QF +YQLLR LKYIH A + HRDLKP N+ N Sbjct: 102 VYLVTTLMGADLNNIVKCQA-LSDEHVQFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNE 160 Query: 203 DCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIF 382 DC+L+I DFGLA + + T YVATRWYRAPE+ ++ Y +DIWS+GCI Sbjct: 161 DCELRILDFGLAPQADEE------MTGYVATRWYRAPEIMLNWM-HYNQTVDIWSVGCIM 213 Query: 383 AELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYLK 523 AELL G+ LFPG + + QL I +++GTPS E L++I +E AR Y++ Sbjct: 214 AELLQGKALFPGNDYIDQLKRIMEVVGTPSPEVLAKISSEHARTYIQ 260
>HOG1_DEBHA (Q9UV50) Mitogen-activated protein kinase HOG1 (EC 2.7.11.24) (MAP| kinase HOG1) Length = 387 Score = 165 bits (417), Expect = 1e-40 Identities = 81/167 (48%), Positives = 113/167 (67%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANA 202 IY V EL +DLH+++ + L + Q+F YQ+LR LKY+H A V HRDLKP NIL N Sbjct: 96 IYFVTELQGTDLHRLLTSRP-LEKQFIQYFTYQILRGLKYVHSAGVIHRDLKPSNILINE 154 Query: 203 DCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIF 382 +C LKICDFGLAR+ T YV+TR+YRAPE+ + + KY +D+WS+GCI Sbjct: 155 NCDLKICDFGLARIQDPQ------MTGYVSTRYYRAPEIMLT-WQKYDTEVDLWSVGCIL 207 Query: 383 AELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYLK 523 +E++ G+PLFPGK+ VHQ IIT+LLG+P + + I +E R+++ Sbjct: 208 SEMIEGKPLFPGKDHVHQFSIITELLGSPPPDVIETICSENTLRFVQ 254
>KKQ1_YEAST (P36005) Probable serine/threonine-protein kinase YKL161C (EC| 2.7.11.1) Length = 433 Score = 164 bits (415), Expect = 2e-40 Identities = 84/172 (48%), Positives = 113/172 (65%), Gaps = 1/172 (0%) Frame = +2 Query: 8 GNSKXIYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKN 187 G +Y+ ELME DL Q+IR+ L H+Q F+YQ+L ALKYIH ANV H DLKPKN Sbjct: 99 GALNGVYLYEELMECDLSQIIRSEQRLEDAHFQSFIYQILCALKYIHSANVLHCDLKPKN 158 Query: 188 ILANADCKLKICDFGLA-RVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIW 364 +L N+DC+LKIC+FGL+ S N + F Y+ + WY+APE+ + + + T A+DIW Sbjct: 159 LLVNSDCQLKICNFGLSCSYSENHKVNDGFIKGYITSIWYKAPEILLN-YQECTKAVDIW 217 Query: 365 SIGCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYL 520 S GCI AELL +P+F GK+ V L+ I +LGTP ETL I ++K Y+ Sbjct: 218 STGCILAELLGRKPMFEGKDYVDHLNHILQILGTPPEETLQEIASQKVYNYI 269
>MK11_HUMAN (Q15759) Mitogen-activated protein kinase 11 (EC 2.7.11.24)| (Mitogen-activated protein kinase p38 beta) (MAP kinase p38 beta) (p38b) (p38-2) (Stress-activated protein kinase 2) Length = 372 Score = 162 bits (411), Expect = 5e-40 Identities = 82/174 (47%), Positives = 112/174 (64%), Gaps = 7/174 (4%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRANDDLTA-------EHYQFFLYQLLRALKYIHGANVFHRDLKP 181 +Y+V LM +DL+ +++ EH QF +YQLLR LKYIH A + HRDLKP Sbjct: 102 VYLVTTLMGADLNNIVKCQAGAHQGARLALDEHVQFLVYQLLRGLKYIHSAGIIHRDLKP 161 Query: 182 KNILANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDI 361 N+ N DC+L+I DFGLAR + + T YVATRWYRAPE+ ++ Y +DI Sbjct: 162 SNVAVNEDCELRILDFGLARQADEE------MTGYVATRWYRAPEIMLNWM-HYNQTVDI 214 Query: 362 WSIGCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYLK 523 WS+GCI AELL G+ LFPG + + QL I +++GTPS E L++I +E AR Y++ Sbjct: 215 WSVGCIMAELLQGKALFPGSDYIDQLKRIMEVVGTPSPEVLAKISSEHARTYIQ 268
>MK15_RAT (Q9Z2A6) Mitogen-activated protein kinase 15 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 7) Length = 547 Score = 162 bits (409), Expect = 9e-40 Identities = 83/185 (44%), Positives = 116/185 (62%), Gaps = 2/185 (1%) Frame = +2 Query: 11 NSKXIYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNI 190 N + IY+VFE M++DL+ VI+ L H + YQLLRA K+IH V HRD KP N+ Sbjct: 85 NDRDIYLVFESMDTDLNAVIQKGRLLEDIHKRCIFYQLLRATKFIHSGRVIHRDQKPANV 144 Query: 191 LANADCKLKICDFGLAR--VSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIW 364 L +A C++K+CDFGLAR F + P T+YVATRWYRAPE+ S YTP +D+W Sbjct: 145 LLDAACRVKLCDFGLARSLSDFPEGPGGQALTEYVATRWYRAPEVLLS-SRWYTPGVDMW 203 Query: 365 SIGCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYLKLHAKKTS 544 S+GCI E+L G+PLFPG + HQL++I + + PS E L + ++ + L+ + Sbjct: 204 SLGCILGEMLRGQPLFPGTSTFHQLELILETIPLPSMEELQGLGSDYSALILQNLGSRPR 263 Query: 545 CALDS 559 LD+ Sbjct: 264 QTLDA 268
>MK15_HUMAN (Q8TD08) Mitogen-activated protein kinase 15 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 8) Length = 544 Score = 160 bits (404), Expect = 3e-39 Identities = 78/160 (48%), Positives = 107/160 (66%), Gaps = 2/160 (1%) Frame = +2 Query: 11 NSKXIYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNI 190 N + IY+VFE M++DL+ VIR L H + YQLLRA +++H +V HRD KP N+ Sbjct: 84 NDRDIYLVFEFMDTDLNAVIRKGGLLQDVHVRSIFYQLLRATRFLHSGHVVHRDQKPSNV 143 Query: 191 LANADCKLKICDFGLARV--SFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIW 364 L +A+C +K+CDFGLAR + P T+YVATRWYRAPE+ S +YT +D+W Sbjct: 144 LLDANCTVKLCDFGLARSLGDLPEGPEDQAVTEYVATRWYRAPEVLLS-SHRYTLGVDMW 202 Query: 365 SIGCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETL 484 S+GCI E+L GRPLFPG + +HQL++I + + PS E L Sbjct: 203 SLGCILGEMLRGRPLFPGTSTLHQLELILETIPPPSEEDL 242
>YPC2_CAEEL (Q11179) Putative serine/threonine-protein kinase C05D10.2 in| chromosome III (EC 2.7.11.24) Length = 470 Score = 159 bits (402), Expect = 6e-39 Identities = 80/187 (42%), Positives = 117/187 (62%), Gaps = 5/187 (2%) Frame = +2 Query: 11 NSKXIYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNI 190 N + IY+ FE ME+DLH VI+ L H Q+ + QL RA++++H NV HRDLKP N+ Sbjct: 84 NDRDIYLAFEFMEADLHNVIKKGSILKDVHKQYIMCQLFRAIRFLHSGNVLHRDLKPSNV 143 Query: 191 LANADCKLKICDFGLAR--VSFNDAPSAIFW---TDYVATRWYRAPELCGSFFSKYTPAI 355 L +ADC++K+ DFGLAR S D P T+YVATRWYR+PE+ + +YT + Sbjct: 144 LLDADCRVKLADFGLARSLSSLEDYPEGQKMPDLTEYVATRWYRSPEILLA-AKRYTKGV 202 Query: 356 DIWSIGCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYLKLHAK 535 D+WS+GCI AE+L GR LFPG + ++Q++ I + + PS ++ I + A L+ + Sbjct: 203 DMWSLGCILAEMLIGRALFPGSSTINQIERIMNTIAKPSRADIASIGSHYAASVLEKMPQ 262 Query: 536 KTSCALD 556 + LD Sbjct: 263 RPRKPLD 269
>MK15_MOUSE (Q80Y86) Mitogen-activated protein kinase 15 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 7) Length = 549 Score = 157 bits (398), Expect = 2e-38 Identities = 81/185 (43%), Positives = 114/185 (61%), Gaps = 2/185 (1%) Frame = +2 Query: 11 NSKXIYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNI 190 N + IY+VFE M++DL+ VI+ L H + YQLLRA K+IH V HRD KP N+ Sbjct: 85 NDRDIYLVFESMDTDLNAVIQKGRLLKDIHKRCIFYQLLRATKFIHSGRVIHRDQKPANV 144 Query: 191 LANADCKLKICDFGLARV--SFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIW 364 L ++ C++K+CDFGLAR + P T+YVATRWYRAPE+ S YTP +D+W Sbjct: 145 LLDSACRVKLCDFGLARSLGDLPEGPGGQALTEYVATRWYRAPEVLLS-SRWYTPGVDMW 203 Query: 365 SIGCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYLKLHAKKTS 544 S+GCI E+L G+PLFPG + HQL++I + PS E L + ++ + L+ + Sbjct: 204 SLGCILGEMLRGQPLFPGTSTFHQLELILKTIPLPSMEELQDLGSDYSALILQNLGSRPQ 263 Query: 545 CALDS 559 LD+ Sbjct: 264 QTLDA 268
>PMK2_CAEEL (Q8MXI4) Mitogen-activated protein kinase pmk-2 (EC 2.7.11.24) (p38| MAP kinase 2) (Stress-activated protein kinase pmk-2) Length = 419 Score = 152 bits (384), Expect = 7e-37 Identities = 85/184 (46%), Positives = 111/184 (60%), Gaps = 17/184 (9%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANA 202 +Y V LM SDL +++ LT E Q +YQ+LR LKYIH A + HRDLKP NI N Sbjct: 127 VYFVSVLMGSDLQNIMKIQR-LTDEQIQLLIYQVLRGLKYIHSAGIIHRDLKPSNIAVNE 185 Query: 203 DCKLK-----------------ICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSF 331 C++K I DFGLAR DA T YVATRWYRAPE+ ++ Sbjct: 186 RCEVKVFLSFSQLSFLILSFFKILDFGLARAQ--DAEM----TGYVATRWYRAPEIMLNW 239 Query: 332 FSKYTPAIDIWSIGCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKAR 511 YT +D+WS+GCI AEL++GRPLFPG + + QL I ++GTP E S+I++E+AR Sbjct: 240 MH-YTQTVDVWSVGCILAELVSGRPLFPGDDHIDQLTKIMSVVGTPKEEFWSKIQSEEAR 298 Query: 512 RYLK 523 Y+K Sbjct: 299 NYIK 302
>MK12_HUMAN (P53778) Mitogen-activated protein kinase 12 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 6) (ERK-6) (ERK5) (Stress-activated protein kinase 3) (Mitogen-activated protein kinase p38 gamma) (MAP kinase p38 gamma) Length = 367 Score = 151 bits (381), Expect = 2e-36 Identities = 73/166 (43%), Positives = 113/166 (68%) Frame = +2 Query: 26 YVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANAD 205 Y+V M +DL ++++ ++ L + QF +YQ+L+ L+YIH A + HRDLKP N+ N D Sbjct: 106 YLVMPFMGTDLGKLMK-HEKLGEDRIQFLVYQMLKGLRYIHAAGIIHRDLKPGNLAVNED 164 Query: 206 CKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIFA 385 C+LKI DFGLAR + ++ T YV TRWYRAPE+ ++ +YT +DIWS+GCI A Sbjct: 165 CELKILDFGLARQADSE------MTGYVVTRWYRAPEVILNWM-RYTQTVDIWSVGCIMA 217 Query: 386 ELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYLK 523 E++TG+ LF G + + QL I + GTP +E + R+++++A+ Y+K Sbjct: 218 EMITGKTLFKGSDHLDQLKEIMKVTGTPPAEFVQRLQSDEAKNYMK 263
>MK12_BRARE (O42376) Mitogen-activated protein kinase 12 (EC 2.7.11.24)| (Stress-activated protein kinase 3) Length = 363 Score = 150 bits (378), Expect = 3e-36 Identities = 76/165 (46%), Positives = 110/165 (66%) Frame = +2 Query: 26 YVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANAD 205 Y+V M +DL ++++ + L+ E Q+ +YQ+L+ LKYIH A + HRDLKP N+ N + Sbjct: 104 YLVMPFMGTDLGKLMKM-ERLSEERVQYLVYQMLKGLKYIHAAGIIHRDLKPGNLAINEE 162 Query: 206 CKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIFA 385 C+LKI DFGLAR + ++ T YV TRWYRAPE+ S+ YT +DIWS+GCI A Sbjct: 163 CELKILDFGLARQTDSE------MTGYVVTRWYRAPEVILSWM-HYTQTVDIWSVGCIMA 215 Query: 386 ELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYL 520 E+L G+PLF G + + QL I + GTPS E +++++E AR Y+ Sbjct: 216 EMLLGKPLFKGHDHLDQLMEIMKVTGTPSKEFTAKLQSEDARNYV 260
>PMK3_CAEEL (O44514) Mitogen-activated protein kinase pmk-3 (EC 2.7.11.24) (p38| MAP kinase 3) (Stress-activated protein kinase pmk-3) Length = 474 Score = 149 bits (377), Expect = 4e-36 Identities = 79/169 (46%), Positives = 103/169 (60%), Gaps = 5/169 (2%) Frame = +2 Query: 17 KXIYVVFELMESDLHQVIRANDD-----LTAEHYQFFLYQLLRALKYIHGANVFHRDLKP 181 + +YVV E L+Q+++ D LT EH +F +YQ++RALKYIH AN+ HRDLKP Sbjct: 196 RDVYVVTEFAGRSLYQILKQQRDYGRRVLTDEHIKFIIYQIIRALKYIHSANIIHRDLKP 255 Query: 182 KNILANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDI 361 N+ D L I DFGLAR S +++ T YV TRWYR+PE+ YT D+ Sbjct: 256 GNLALTDDSDLMILDFGLAR-SLEKKDTSL--TQYVQTRWYRSPEVIYWKIDSYTNLADM 312 Query: 362 WSIGCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKA 508 WS+GCI AELLTG PLFPG Q IT L G+P E L++I N+ + Sbjct: 313 WSLGCIAAELLTGEPLFPGDEPNAQYQRITQLCGSPDEELLTKIENDNS 361
>MK13_RAT (Q9WTY9) Mitogen-activated protein kinase 13 (EC 2.7.11.24)| (Stress-activated protein kinase 4) (Mitogen-activated protein kinase p38 delta) (MAP kinase p38 delta) Length = 366 Score = 149 bits (375), Expect = 7e-36 Identities = 75/171 (43%), Positives = 110/171 (64%) Frame = +2 Query: 11 NSKXIYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNI 190 N + Y+V M++DL +++ + + E Q+ +YQ+L+ LKYIH A + HRDLKP N+ Sbjct: 99 NFQDFYLVMPFMQTDLQKIMGM--EFSEEKVQYLVYQMLKGLKYIHSAGIVHRDLKPGNL 156 Query: 191 LANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSI 370 N DC+LKI DFGLAR DA T YV TRWYRAPE+ S+ Y +DIWS+ Sbjct: 157 AVNEDCELKILDFGLAR--HTDAE----MTGYVVTRWYRAPEVILSWM-HYNQTVDIWSV 209 Query: 371 GCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYLK 523 GCI AE+LTG+ LF GK+ + QL I + G P +E + +++++ A+ Y++ Sbjct: 210 GCIMAEMLTGKTLFKGKDYLDQLTQILKVTGVPGAEFVQKLKDKAAKSYIQ 260
>MK12_MOUSE (O08911) Mitogen-activated protein kinase 12 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 6) (ERK-6) (Stress-activated protein kinase 3) (Mitogen-activated protein kinase p38 gamma) (MAP kinase p38 gamma) Length = 367 Score = 149 bits (375), Expect = 7e-36 Identities = 73/166 (43%), Positives = 112/166 (67%) Frame = +2 Query: 26 YVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANAD 205 Y+V M +DL ++++ ++ L+ + QF +YQ+L+ LKYIH A V HRDLKP N+ N D Sbjct: 106 YLVMPFMGTDLGKLMK-HETLSEDRIQFLVYQMLKGLKYIHAAGVIHRDLKPGNLAVNED 164 Query: 206 CKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIFA 385 C+LKI DFGLAR + ++ T YV TRWYRAPE+ ++ +YT +DIWS+GCI A Sbjct: 165 CELKILDFGLARQADSE------MTGYVVTRWYRAPEVILNWM-RYTQTVDIWSVGCIMA 217 Query: 386 ELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYLK 523 E++TG+ LF G + + QL I + GTP E + ++++ +A+ Y++ Sbjct: 218 EMITGKILFKGNDHLDQLKEIMKITGTPPPEFVQKLQSAEAKNYME 263
>MK12_RAT (Q63538) Mitogen-activated protein kinase 12 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 6) (ERK-6) (Stress-activated protein kinase 3) (Mitogen-activated protein kinase p38 gamma) (MAP kinase p38 gamma) Length = 367 Score = 148 bits (374), Expect = 1e-35 Identities = 73/166 (43%), Positives = 112/166 (67%) Frame = +2 Query: 26 YVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANAD 205 Y+V M +DL ++++ ++ L+ + QF +YQ+L+ LKYIH A V HRDLKP N+ N D Sbjct: 106 YLVMPFMGTDLGKLMK-HETLSEDRIQFLVYQMLKGLKYIHAAGVIHRDLKPGNLAVNED 164 Query: 206 CKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIFA 385 C+LKI DFGLAR + ++ T YV TRWYRAPE+ ++ +YT +DIWS+GCI A Sbjct: 165 CELKILDFGLARQADSE------MTGYVVTRWYRAPEVILNWM-RYTQTVDIWSVGCIMA 217 Query: 386 ELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYLK 523 E++TG+ LF G + + QL I + GTP E + ++++ +A+ Y++ Sbjct: 218 EMITGKILFKGNDHLDQLKEIMKVTGTPPPEFVQKLQSAEAKNYME 263
>MK14C_DROME (P83100) Putative mitogen-activated protein kinase 14C (EC| 2.7.11.24) (MAP kinase p38c) Length = 356 Score = 147 bits (370), Expect = 3e-35 Identities = 75/175 (42%), Positives = 113/175 (64%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANA 202 +Y+V LM++DLH+ R+ ++ + + LYQ+LR LKYIH A V HRDLKP NI N Sbjct: 99 VYLVTHLMDADLHRYSRSKR-MSDQEIRIILYQILRGLKYIHSAGVVHRDLKPCNIAVNG 157 Query: 203 DCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIF 382 + +++I DFGL+R+ + TD+V T WY APE+ +YT AID+WS+GCI Sbjct: 158 NSEVRILDFGLSRMCADKM------TDHVGTMWYLAPEII-FLRGQYTKAIDVWSVGCIL 210 Query: 383 AELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYLKLHAKKTSC 547 AEL+T R LF G+N V Q+ + +++GTP+ E ++ I E++R YL+ + + C Sbjct: 211 AELITDRVLFRGENYVSQIRCLINIMGTPTREFITGISMERSRNYLEGYPLRQRC 265
>MK13_PANTR (Q9N272) Mitogen-activated protein kinase 13 (EC 2.7.11.24)| (Stress-activated protein kinase 4) Length = 365 Score = 147 bits (370), Expect = 3e-35 Identities = 76/171 (44%), Positives = 108/171 (63%) Frame = +2 Query: 11 NSKXIYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNI 190 N Y+V M++DL +++ + + E Q+ +YQ+L+ LKYIH A V HRDLKP N+ Sbjct: 99 NFHDFYLVMXFMQTDLQKIMXM--EFSEEKIQYLVYQMLKGLKYIHSAGVVHRDLKPGNL 156 Query: 191 LANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSI 370 N DC+LKI DFGLAR + DA T YV TRWYRAPE+ S+ Y +DIWS+ Sbjct: 157 AVNEDCELKILDFGLARHA--DAE----MTGYVVTRWYRAPEVILSWM-HYNQTVDIWSV 209 Query: 371 GCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYLK 523 GCI AE+LTG+ LF GK+ + QL I + G P +E + ++ + A+ Y++ Sbjct: 210 GCIMAEMLTGKTLFKGKDYLDQLTQILKVTGVPGTEFVQKLNDXAAKSYIQ 260
>MK13_HUMAN (O15264) Mitogen-activated protein kinase 13 (EC 2.7.11.24)| (Stress-activated protein kinase 4) (Mitogen-activated protein kinase p38 delta) (MAP kinase p38 delta) Length = 365 Score = 147 bits (370), Expect = 3e-35 Identities = 76/171 (44%), Positives = 109/171 (63%) Frame = +2 Query: 11 NSKXIYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNI 190 N Y+V M++DL +++ + + E Q+ +YQ+L+ LKYIH A V HRDLKP N+ Sbjct: 99 NFYDFYLVMPFMQTDLQKIMGM--EFSEEKIQYLVYQMLKGLKYIHSAGVVHRDLKPGNL 156 Query: 191 LANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSI 370 N DC+LKI DFGLAR + DA T YV TRWYRAPE+ S+ Y +DIWS+ Sbjct: 157 AVNEDCELKILDFGLARHA--DAE----MTGYVVTRWYRAPEVILSWM-HYNQTVDIWSV 209 Query: 371 GCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYLK 523 GCI AE+LTG+ LF GK+ + QL I + G P +E + ++ ++ A+ Y++ Sbjct: 210 GCIMAEMLTGKTLFKGKDYLDQLTQILKVTGVPGTEFVQKLNDKAAKSYIQ 260
>MK13_MOUSE (Q9Z1B7) Mitogen-activated protein kinase 13 (EC 2.7.11.24)| (Stress-activated protein kinase 4) (Mitogen-activated protein kinase p38 delta) (MAP kinase p38 delta) Length = 366 Score = 146 bits (368), Expect = 5e-35 Identities = 71/166 (42%), Positives = 108/166 (65%) Frame = +2 Query: 26 YVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANAD 205 Y+V M++DL +++ + + + Q+ +YQ+L+ LKYIH A + HRDLKP N+ N D Sbjct: 104 YLVMPFMQTDLQKIMGM--EFSEDKVQYLVYQMLKGLKYIHSAGIVHRDLKPGNLAVNED 161 Query: 206 CKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIFA 385 C+LKI DFGLAR + + T YV TRWYRAPE+ S+ Y +DIWS+GCI A Sbjct: 162 CELKILDFGLARHTDTE------MTGYVVTRWYRAPEVILSWM-HYNQTVDIWSVGCIMA 214 Query: 386 ELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYLK 523 E+LTG+ LF GK+ + QL I + G P +E + +++++ A+ Y++ Sbjct: 215 EMLTGKTLFKGKDYLDQLTQILKVTGVPGAEFVQKLKDKAAKSYIQ 260
>JNK1_ANCCA (Q9U6D2) Stress-activated protein kinase JNK-1 (EC 2.7.11.24)| Length = 376 Score = 145 bits (366), Expect = 8e-35 Identities = 78/171 (45%), Positives = 107/171 (62%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANA 202 +Y+V ELM+++L QVI+ DL E + LYQ+L +K++H A + HRDLKP NI+ + Sbjct: 104 LYIVMELMDANLCQVIQM--DLDHERLSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKS 161 Query: 203 DCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIF 382 DC LKI DFGLAR A A T YV TR+YRAPE+ Y +D+WS+GCIF Sbjct: 162 DCTLKILDFGLART----AVEAFMMTPYVVTRYYRAPEVI--LGMGYGENVDVWSVGCIF 215 Query: 383 AELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYLKLHAK 535 EL+ GR LFPG + + Q I +LLGTP + L+R++ R Y++ K Sbjct: 216 GELIRGRVLFPGADHIDQWTRIIELLGTPEPQFLARLQT-TVRNYVENRQK 265
>SMK1_YEAST (P41808) Sporulation-specific mitogen-activated protein kinase SMK1| (EC 2.7.11.24) (MAP kinase SMK1) Length = 388 Score = 142 bits (357), Expect = 9e-34 Identities = 78/167 (46%), Positives = 106/167 (63%), Gaps = 5/167 (2%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANA 202 +Y EL++ DL +VI ++ L+ H ++FLYQ+L LKYIH A+V HRDLKP NIL Sbjct: 117 LYCYQELIDYDLAKVIHSSVQLSEFHIKYFLYQILCGLKYIHSADVIHRDLKPGNILCTL 176 Query: 203 DCKLKICDFGLAR---VSFNDAPSAI--FWTDYVATRWYRAPELCGSFFSKYTPAIDIWS 367 + LKICDFGLAR F S + T+YVATRWYRAPEL S Y+ ++DIW+ Sbjct: 177 NGCLKICDFGLARGIHAGFFKCHSTVQPHITNYVATRWYRAPELLLS-NQPYSKSVDIWA 235 Query: 368 IGCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKA 508 +GCI AE +P+F G++ +HQ+ I +LGTP + L + KA Sbjct: 236 VGCILAEFYARKPVFMGRDSMHQIFEIIKVLGTPDKDILIKFGTIKA 282
>MK08_BRARE (Q9DGD9) Mitogen-activated protein kinase 8 (EC 2.7.11.24)| (Stress-activated protein kinase JNK1) (c-Jun N-terminal kinase 1) Length = 384 Score = 140 bits (354), Expect = 2e-33 Identities = 73/167 (43%), Positives = 107/167 (64%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANA 202 +Y+V ELM+++L QVI+ +L E + LYQ+L +K++H A + HRDLKP NI+ + Sbjct: 104 VYLVMELMDANLCQVIQM--ELDHERLSYLLYQMLCGIKHLHAAGIIHRDLKPSNIVVKS 161 Query: 203 DCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIF 382 DC LKI DFGLAR A + + T YV TR+YRAPE+ Y +D+WSIGCI Sbjct: 162 DCTLKILDFGLART----AATGLLMTPYVVTRYYRAPEVI--LGMGYQANVDVWSIGCIM 215 Query: 383 AELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYLK 523 AE++ G LFPG + + Q + + + LGTPS E + ++ N+ R Y++ Sbjct: 216 AEMVRGSVLFPGTDHIDQWNKVIEQLGTPSQEFMMKL-NQSVRTYVE 261
>JNK_DROME (P92208) Stress-activated protein kinase JNK (EC 2.7.11.24) (dJNK)| (Protein basket) Length = 372 Score = 140 bits (354), Expect = 2e-33 Identities = 76/178 (42%), Positives = 108/178 (60%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANA 202 +Y+V ELM+++L QVI+ DL + + LYQ+L +K++H A + HRDLKP NI+ A Sbjct: 102 VYLVMELMDANLCQVIQM--DLDHDRMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKA 159 Query: 203 DCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIF 382 DC LKI DFGLAR A + T YV TR+YRAPE+ YT +DIWS+GCI Sbjct: 160 DCTLKILDFGLART----AGTTFMMTPYVVTRYYRAPEVI--LGMGYTENVDIWSVGCIM 213 Query: 383 AELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYLKLHAKKTSCALD 556 E++ G LFPG + + Q + I + LGTPS + R++ R Y++ + T + D Sbjct: 214 GEMIRGGVLFPGTDHIDQWNKIIEQLGTPSPSFMQRLQ-PTVRNYVENRPRYTGYSFD 270
>MK08B_CYPCA (O42099) Mitogen-activated protein kinase 8B (EC 2.7.11.24)| (Stress-activated protein kinase JNKb) (c-Jun N-terminal kinase B) Length = 427 Score = 140 bits (353), Expect = 3e-33 Identities = 73/178 (41%), Positives = 110/178 (61%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANA 202 +Y+V ELM+++L QVI+ +L E + LYQ+L K++H A + HRDLKP NI+ + Sbjct: 104 VYLVMELMDANLCQVIQM--ELDHERLSYLLYQMLCGTKHLHSAGIIHRDLKPSNIVVKS 161 Query: 203 DCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIF 382 DC LKI DFGLAR A + + T YV TR+YRAPE+ Y +D+WS+GCI Sbjct: 162 DCTLKILDFGLART----AATGLLMTPYVVTRYYRAPEVI--LGMGYQANVDVWSVGCIM 215 Query: 383 AELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYLKLHAKKTSCALD 556 AE++ G LFPG + + Q + + + LGTPS E + ++ N+ R Y++ + T + + Sbjct: 216 AEMVRGSVLFPGSDHIDQWNKVIEQLGTPSQEFMMKL-NQSVRTYVENRPRYTGYSFE 272
>MK08A_CYPCA (Q90327) Mitogen-activated protein kinase 8A (EC 2.7.11.24)| (Stress-activated protein kinase JNKa) (c-Jun N-terminal kinase A) Length = 427 Score = 140 bits (352), Expect = 3e-33 Identities = 72/178 (40%), Positives = 112/178 (62%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANA 202 +Y+V ELM+++L QVI+ +L E + LYQ+L +K++H A + HRDLKP NI+ + Sbjct: 104 VYLVMELMDANLCQVIQM--ELDHERLSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKS 161 Query: 203 DCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIF 382 DC LKI DFGLAR A + + T YV TR+YRAPE+ Y +DIWS+GCI Sbjct: 162 DCTLKILDFGLART----AATGLLMTPYVVTRYYRAPEVI--LGMGYQANVDIWSVGCIL 215 Query: 383 AELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYLKLHAKKTSCALD 556 AE++ + LFPG++ + Q + + + LGTP+ E + ++ N+ R Y++ + T + + Sbjct: 216 AEMVRHKILFPGRDYIDQWNKVIEQLGTPTQEFMMKL-NQSVRTYVENRPRYTGYSFE 272
>JNK1_CAEEL (Q8WQG9) Stress-activated protein kinase jnk-1 (EC 2.7.11.24)| Length = 463 Score = 140 bits (352), Expect = 3e-33 Identities = 74/158 (46%), Positives = 99/158 (62%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANA 202 +Y+V ELM+++L QVI+ DL E + LYQ+L ++++H A + HRDLKP NI+ + Sbjct: 197 LYIVMELMDANLCQVIQM--DLDHERLSYLLYQMLCGIRHLHSAGIIHRDLKPSNIVVRS 254 Query: 203 DCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIF 382 DC LKI DFGLAR A A T YV TR+YRAPE+ Y +D+WSIGCIF Sbjct: 255 DCTLKILDFGLART----AIEAFMMTPYVVTRYYRAPEVI--LGMGYKENVDVWSIGCIF 308 Query: 383 AELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIR 496 EL+ GR LFPG + + Q I + LGTP L R++ Sbjct: 309 GELIRGRVLFPGGDHIDQWTRIIEQLGTPDRSFLERLQ 346
>JNK_SUBDO (Q966Y3) Stress-activated protein kinase JNK (EC 2.7.11.24)| Length = 361 Score = 137 bits (345), Expect = 2e-32 Identities = 71/151 (47%), Positives = 96/151 (63%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANA 202 +Y+V ELM+++L +VI +L + + LYQLL +K++H A + HRDLKP NI+ Sbjct: 100 VYIVMELMDANLCRVIGI--ELDHDRMSYLLYQLLCGIKHLHSAGIIHRDLKPSNIVVKE 157 Query: 203 DCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIF 382 DC LKI DFGLAR A T YV TR+YRAPE+ KY +DIWS+GCIF Sbjct: 158 DCSLKILDFGLART----ADQTFNMTPYVVTRYYRAPEVIVGM--KYKENVDIWSVGCIF 211 Query: 383 AELLTGRPLFPGKNVVHQLDIITDLLGTPSS 475 AE++ G L PGK+ + Q + +T +LGTP S Sbjct: 212 AEMIRGDILLPGKDYIDQWNKVTQVLGTPPS 242
>MK09_MOUSE (Q9WTU6) Mitogen-activated protein kinase 9 (EC 2.7.11.24)| (Stress-activated protein kinase JNK2) (c-Jun N-terminal kinase 2) Length = 423 Score = 136 bits (342), Expect = 5e-32 Identities = 72/171 (42%), Positives = 107/171 (62%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANA 202 +Y+V ELM+++L QVI +L E + LYQ+L +K++H A + HRDLKP NI+ + Sbjct: 104 VYLVMELMDANLCQVIHM--ELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKS 161 Query: 203 DCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIF 382 DC LKI DFGLAR A + T YV TR+YRAPE+ Y +DIWS+GCI Sbjct: 162 DCTLKILDFGLART----ACTNFMMTPYVVTRYYRAPEVI--LGMGYKENVDIWSVGCIM 215 Query: 383 AELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYLKLHAK 535 AE++ + LFPG++ + Q + + + LGTPS+E + +++ R Y++ K Sbjct: 216 AEMVLHKVLFPGRDYIDQWNKVIEQLGTPSAEFMKKLQ-PTVRNYVENRPK 265
>MK10_RAT (P49187) Mitogen-activated protein kinase 10 (EC 2.7.11.24)| (Stress-activated protein kinase JNK3) (c-Jun N-terminal kinase 3) (SAPK-beta) (p54-beta) Length = 464 Score = 135 bits (341), Expect = 7e-32 Identities = 71/171 (41%), Positives = 107/171 (62%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANA 202 +Y+V ELM+++L QVI+ +L E + LYQ+L A+K++H A + HRDLKP NI+ + Sbjct: 142 VYLVMELMDANLCQVIQM--ELDHERMSYLLYQMLSAIKHLHSAGIIHRDLKPSNIVVKS 199 Query: 203 DCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIF 382 DC LKI DFGLAR A ++ T YV TR+YRAPE+ Y +DIWS+GCI Sbjct: 200 DCTLKILDFGLART----AGTSFMMTPYVVTRYYRAPEVI--LGMGYKENVDIWSVGCIM 253 Query: 383 AELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYLKLHAK 535 E++ + LFPG++ + Q + + + LGTP E + +++ R Y++ K Sbjct: 254 GEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQ-PTVRNYVENRPK 303
>PCTK2_HUMAN (Q00537) Serine/threonine-protein kinase PCTAIRE-2 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 2) Length = 523 Score = 135 bits (339), Expect = 1e-31 Identities = 77/170 (45%), Positives = 106/170 (62%), Gaps = 3/170 (1%) Frame = +2 Query: 17 KXIYVVFELMESDLHQVIRANDDLTAEH-YQFFLYQLLRALKYIHGANVFHRDLKPKNIL 193 K + +VFE ++ DL Q + ++ + H + FLYQ+LR L Y H V HRDLKP+N+L Sbjct: 261 KSLTLVFEYLDKDLKQYMDDCGNIMSMHNVKLFLYQILRGLAYCHRRKVLHRDLKPQNLL 320 Query: 194 ANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPE-LCGSFFSKYTPAIDIWSI 370 N +LK+ DFGLAR P+ + ++ V T WYR P+ L GS S+Y+ ID+W + Sbjct: 321 INEKGELKLADFGLARAK--SVPTKTY-SNEVVTLWYRPPDVLLGS--SEYSTQIDMWGV 375 Query: 371 GCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRI-RNEKARRY 517 GCIF E+ +GRPLFPG V +L +I LLGTPS ET I NE+ + Y Sbjct: 376 GCIFFEMASGRPLFPGSTVEDELHLIFRLLGTPSQETWPGISSNEEFKNY 425
>MK08_XENLA (Q8QHK8) Mitogen-activated protein kinase 8 (EC 2.7.11.24)| (Stress-activated protein kinase JNK1) Length = 426 Score = 134 bits (338), Expect = 1e-31 Identities = 68/158 (43%), Positives = 101/158 (63%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANA 202 +Y+V ELM+++L QVI+ +L E + LYQ+L +K++H A + HRDLKP NI+ + Sbjct: 104 LYIVMELMDANLCQVIQM--ELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKS 161 Query: 203 DCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIF 382 DC LKI DFGLAR A ++ T YV TR+YRAPE+ Y +DIWS+GCI Sbjct: 162 DCTLKILDFGLART----AGTSFMMTPYVVTRYYRAPEVI--LGMGYKENVDIWSVGCIL 215 Query: 383 AELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIR 496 E++ G LFPG + + Q + + + LGTP +E + +++ Sbjct: 216 GEMIKGGVLFPGTDHIDQWNKVIEQLGTPCTEFMKKLQ 253
>MK10_MOUSE (Q61831) Mitogen-activated protein kinase 10 (EC 2.7.11.24)| (Stress-activated protein kinase JNK3) (c-Jun N-terminal kinase 3) (MAP kinase p49 3F12) Length = 464 Score = 133 bits (335), Expect = 3e-31 Identities = 70/171 (40%), Positives = 106/171 (61%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANA 202 +Y+V ELM+++L QVI+ +L E + LYQ+L +K++H A + HRDLKP NI+ + Sbjct: 142 VYLVMELMDANLCQVIQM--ELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKS 199 Query: 203 DCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIF 382 DC LKI DFGLAR A ++ T YV TR+YRAPE+ Y +DIWS+GCI Sbjct: 200 DCTLKILDFGLART----AGTSFMMTPYVVTRYYRAPEVI--LGMGYKENVDIWSVGCIM 253 Query: 383 AELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYLKLHAK 535 E++ + LFPG++ + Q + + + LGTP E + +++ R Y++ K Sbjct: 254 GEMVRHKILFPGRSYIDQWNKVIEQLGTPCPEFMKKLQ-PTVRNYVENRPK 303
>MK10_HUMAN (P53779) Mitogen-activated protein kinase 10 (EC 2.7.11.24)| (Stress-activated protein kinase JNK3) (c-Jun N-terminal kinase 3) (MAP kinase p49 3F12) Length = 464 Score = 133 bits (335), Expect = 3e-31 Identities = 70/171 (40%), Positives = 106/171 (61%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANA 202 +Y+V ELM+++L QVI+ +L E + LYQ+L +K++H A + HRDLKP NI+ + Sbjct: 142 VYLVMELMDANLCQVIQM--ELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKS 199 Query: 203 DCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIF 382 DC LKI DFGLAR A ++ T YV TR+YRAPE+ Y +DIWS+GCI Sbjct: 200 DCTLKILDFGLART----AGTSFMMTPYVVTRYYRAPEVI--LGMGYKENVDIWSVGCIM 253 Query: 383 AELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYLKLHAK 535 E++ + LFPG++ + Q + + + LGTP E + +++ R Y++ K Sbjct: 254 GEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQ-PTVRNYVENRPK 303
>MK08_MOUSE (Q91Y86) Mitogen-activated protein kinase 8 (EC 2.7.11.24)| (Stress-activated protein kinase JNK1) (c-Jun N-terminal kinase 1) Length = 384 Score = 133 bits (334), Expect = 4e-31 Identities = 66/158 (41%), Positives = 101/158 (63%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANA 202 +Y+V ELM+++L QVI+ +L E + LYQ+L +K++H A + HRDLKP NI+ + Sbjct: 104 VYIVMELMDANLCQVIQM--ELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKS 161 Query: 203 DCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIF 382 DC LKI DFGLAR A ++ T YV TR+YRAPE+ Y +D+WS+GCI Sbjct: 162 DCTLKILDFGLART----AGTSFMMTPYVVTRYYRAPEVI--LGMGYKENVDLWSVGCIM 215 Query: 383 AELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIR 496 E++ + LFPG++ + Q + + + LGTP E + +++ Sbjct: 216 GEMVCHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQ 253
>MK08_HUMAN (P45983) Mitogen-activated protein kinase 8 (EC 2.7.11.24)| (Stress-activated protein kinase JNK1) (c-Jun N-terminal kinase 1) (JNK-46) Length = 427 Score = 133 bits (334), Expect = 4e-31 Identities = 66/158 (41%), Positives = 101/158 (63%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANA 202 +Y+V ELM+++L QVI+ +L E + LYQ+L +K++H A + HRDLKP NI+ + Sbjct: 104 VYIVMELMDANLCQVIQM--ELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKS 161 Query: 203 DCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIF 382 DC LKI DFGLAR A ++ T YV TR+YRAPE+ Y +D+WS+GCI Sbjct: 162 DCTLKILDFGLART----AGTSFMMTPYVVTRYYRAPEVI--LGMGYKENVDLWSVGCIM 215 Query: 383 AELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIR 496 E++ + LFPG++ + Q + + + LGTP E + +++ Sbjct: 216 GEMVCHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQ 253
>PCTK2_MOUSE (Q8K0D0) Serine/threonine-protein kinase PCTAIRE-2 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 2) Length = 523 Score = 133 bits (334), Expect = 4e-31 Identities = 75/170 (44%), Positives = 106/170 (62%), Gaps = 3/170 (1%) Frame = +2 Query: 17 KXIYVVFELMESDLHQVIRANDDLTAEH-YQFFLYQLLRALKYIHGANVFHRDLKPKNIL 193 K + +VFE ++ DL Q + ++ + H + FLYQ+LR L Y H V HRDLKP+N+L Sbjct: 261 KSLTLVFEYLDKDLKQYMDDCGNIMSMHNVKLFLYQILRGLAYCHRRKVLHRDLKPQNLL 320 Query: 194 ANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPE-LCGSFFSKYTPAIDIWSI 370 N +LK+ DFGLAR P+ + ++ V T WYR P+ L GS S+Y+ ID+W + Sbjct: 321 INERGELKLADFGLARAK--SVPTKTY-SNEVVTLWYRPPDVLLGS--SEYSTQIDMWGV 375 Query: 371 GCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRI-RNEKARRY 517 GCIF E+ +GRPLFPG V +L +I LLGTPS ET + N++ + Y Sbjct: 376 GCIFFEMASGRPLFPGSTVEDELHLIFRLLGTPSQETWPGVSSNDEFKNY 425
>CCRK_PONPY (Q5R7I7) Cell cycle-related kinase (EC 2.7.11.22)| Length = 346 Score = 132 bits (333), Expect(2) = 5e-31 Identities = 71/157 (45%), Positives = 95/157 (60%), Gaps = 1/157 (0%) Frame = +2 Query: 11 NSKXIYVVFELMESDLHQVIR-ANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKN 187 +S + FE M SDL +V+R A L + +L LL+ + + H N+ HRDLKP N Sbjct: 73 HSAGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVSFCHANNIVHRDLKPAN 132 Query: 188 ILANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWS 367 +L +A +LKI DFGLARV D +T VATRWYRAPEL +Y +D+W+ Sbjct: 133 LLISASGQLKIADFGLARVFSPDGSR--LYTHQVATRWYRAPELLYGA-RQYDQGVDLWA 189 Query: 368 IGCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSE 478 +GCI ELL G PLFPGKN + QL + +LGTP+ + Sbjct: 190 VGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQ 226 Score = 21.2 bits (43), Expect(2) = 5e-31 Identities = 9/28 (32%), Positives = 14/28 (50%) Frame = +3 Query: 498 TRRPGGTLSCMRKKHPVPLTQKFPNADP 581 T P +++ PVPL + P+A P Sbjct: 232 TELPDYNKISFKEQAPVPLEEVLPDASP 259
>CCRK_HUMAN (Q8IZL9) Cell cycle-related kinase (EC 2.7.11.22)| (Cyclin-kinase-activating kinase p42) (CDK-activating kinase p42) (CAK-kinase p42) Length = 346 Score = 132 bits (333), Expect = 6e-31 Identities = 71/151 (47%), Positives = 93/151 (61%), Gaps = 1/151 (0%) Frame = +2 Query: 29 VVFELMESDLHQVIR-ANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANAD 205 + FE M SDL +V+R A L + +L LL+ + + H N+ HRDLKP N+L +A Sbjct: 79 LAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCHANNIVHRDLKPANLLISAS 138 Query: 206 CKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIFA 385 +LKI DFGLARV D +T VATRWYRAPEL +Y +D+WS+GCI Sbjct: 139 GQLKIADFGLARVFSPDGSR--LYTHQVATRWYRAPELLYGA-RQYDQGVDLWSVGCIMG 195 Query: 386 ELLTGRPLFPGKNVVHQLDIITDLLGTPSSE 478 ELL G PLFPGKN + QL + +LGTP+ + Sbjct: 196 ELLNGSPLFPGKNDIEQLCYVLRILGTPNPQ 226
>PCTK2_RAT (O35831) Serine/threonine-protein kinase PCTAIRE-2 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 2) Length = 523 Score = 132 bits (333), Expect = 6e-31 Identities = 75/170 (44%), Positives = 105/170 (61%), Gaps = 3/170 (1%) Frame = +2 Query: 17 KXIYVVFELMESDLHQVIRANDDLTAEH-YQFFLYQLLRALKYIHGANVFHRDLKPKNIL 193 K + +VFE ++ DL Q + + + H + FLYQ+LR L Y H V HRDLKP+N+L Sbjct: 261 KSLTLVFEYLDKDLKQYMDDCGSIMSMHNVKLFLYQILRGLAYCHRRKVLHRDLKPQNLL 320 Query: 194 ANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPE-LCGSFFSKYTPAIDIWSI 370 N +LK+ DFGLAR P+ + ++ V T WYR P+ L GS S+Y+ ID+W + Sbjct: 321 INERGELKLADFGLARAK--SVPTKTY-SNEVVTLWYRPPDVLLGS--SEYSTQIDMWGV 375 Query: 371 GCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRI-RNEKARRY 517 GCIF E+ +GRPLFPG V +L +I LLGTPS ET + N++ + Y Sbjct: 376 GCIFFEMASGRPLFPGSTVEDELHLIFRLLGTPSQETWPGVSSNDEFKNY 425
>MK08_RAT (P49185) Mitogen-activated protein kinase 8 (EC 2.7.11.24)| (Stress-activated protein kinase JNK1) (c-Jun N-terminal kinase 1) (SAPK gamma) (p54 gamma) Length = 411 Score = 132 bits (332), Expect = 7e-31 Identities = 66/158 (41%), Positives = 101/158 (63%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANA 202 +Y+V ELM+++L QVI+ +L E + LYQ+L +K++H A + HRDLKP NI+ + Sbjct: 104 VYIVMELMDANLCQVIQM--ELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKS 161 Query: 203 DCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIF 382 DC LKI DFGLAR A ++ T YV TR+YRAPE+ Y +D+WS+GCI Sbjct: 162 DCTLKILDFGLART----AGTSFMMTPYVVTRYYRAPEVI--LGMGYKENVDLWSVGCIM 215 Query: 383 AELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIR 496 E++ + LFPG++ + Q + + + LGTP E + +++ Sbjct: 216 GEMVCLKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQ 253
>PCTK1_MOUSE (Q04735) Serine/threonine-protein kinase PCTAIRE-1 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 1) (CRK5) Length = 496 Score = 132 bits (331), Expect = 9e-31 Identities = 76/170 (44%), Positives = 103/170 (60%), Gaps = 3/170 (1%) Frame = +2 Query: 17 KXIYVVFELMESDLHQVIR-ANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNIL 193 K + +VFE ++ DL Q + + + + + FL+QLLR L Y H V HRDLKP+N+L Sbjct: 234 KSLTLVFEYLDKDLKQYLDDCGNVINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLL 293 Query: 194 ANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPE-LCGSFFSKYTPAIDIWSI 370 N +LK+ DFGLAR P+ + ++ V T WYR P+ L GS + Y+ ID+W + Sbjct: 294 INERGELKLADFGLARAK--SIPTKTY-SNEVVTLWYRPPDILLGS--TDYSTQIDMWGV 348 Query: 371 GCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRI-RNEKARRY 517 GCIF E+ TGRPLFPG V QL I +LGTP+ ET I NE+ R Y Sbjct: 349 GCIFYEMATGRPLFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFRTY 398
>MK06_MOUSE (Q61532) Mitogen-activated protein kinase 6 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 3) (ERK-3) Length = 720 Score = 131 bits (329), Expect = 2e-30 Identities = 71/145 (48%), Positives = 93/145 (64%), Gaps = 1/145 (0%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANA 202 +Y+V E ME+DL V+ L EH + F+YQLLR LKYIH ANV HRDLKP N+ N Sbjct: 104 VYIVQEYMETDLANVLEQGP-LLEEHARLFMYQLLRGLKYIHSANVLHRDLKPANLFINT 162 Query: 203 -DCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCI 379 D LKI DFGLAR+ ++ + T+WYR+P L S + YT AID+W+ GCI Sbjct: 163 EDLVLKIGDFGLARIMDPHYSHKGHLSEGLVTKWYRSPRLLLS-PNNYTKAIDMWAAGCI 221 Query: 380 FAELLTGRPLFPGKNVVHQLDIITD 454 FAE+LTG+ LF G + + Q+ +I D Sbjct: 222 FAEMLTGKTLFAGAHELEQMQLILD 246
>CDC2H_THEPA (Q27032) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 298 Score = 131 bits (329), Expect = 2e-30 Identities = 74/165 (44%), Positives = 103/165 (62%), Gaps = 2/165 (1%) Frame = +2 Query: 11 NSKXIYVVFELMESDLHQVIRANDD-LTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKN 187 + K + +VFE ++ DL +++ A D L + FLYQ+LR + Y H + HRDLKP+N Sbjct: 71 SEKCLTLVFEYLDQDLKKLLDACDGGLEPTTAKSFLYQILRGISYCHDHRILHRDLKPQN 130 Query: 188 ILANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPE-LCGSFFSKYTPAIDIW 364 +L N + LK+ DFGLAR S +T V T WYRAP+ L GS KY+ A+DIW Sbjct: 131 LLINREGVLKLADFGLARAFAIPVRS---YTHEVVTLWYRAPDVLMGS--KKYSTAVDIW 185 Query: 365 SIGCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRN 499 S+GCIFAE++ G PLFPG + QL I +LGTPS ++ ++ N Sbjct: 186 SVGCIFAEMINGVPLFPGISEQDQLKRIFKILGTPSVDSWPQVVN 230
>MK09_RAT (P49186) Mitogen-activated protein kinase 9 (EC 2.7.11.24)| (Stress-activated protein kinase JNK2) (c-Jun N-terminal kinase 2) (SAPK-alpha) (p54-alpha) Length = 423 Score = 130 bits (328), Expect = 2e-30 Identities = 71/171 (41%), Positives = 104/171 (60%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANA 202 +Y+V ELM+++L QVI +L E + LYQ+L +K++H A + HRDLKP NI+ + Sbjct: 104 VYLVMELMDANLCQVIHM--ELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKS 161 Query: 203 DCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIF 382 DC LKI DFGLAR A + T YV TR+YRAPE+ Y +DIWS+GCI Sbjct: 162 DCTLKILDFGLART----ACTNFMMTPYVVTRYYRAPEVI--LGMGYKENVDIWSVGCIM 215 Query: 383 AELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYLKLHAK 535 EL+ G +F G + + Q + + + LGTPS+E + +++ R Y++ K Sbjct: 216 GELVKGCVIFQGTDHIDQWNKVIEQLGTPSAEFMKKLQ-PTVRNYVENRPK 265
>MK09_CHICK (P79996) Mitogen-activated protein kinase 9 (EC 2.7.11.24)| (Stress-activated protein kinase JNK2) (c-Jun N-terminal kinase 2) Length = 382 Score = 130 bits (328), Expect = 2e-30 Identities = 71/171 (41%), Positives = 104/171 (60%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANA 202 +Y+V ELM+++L QVI +L E + LYQ+L +K++H A + HRDLKP NI+ + Sbjct: 104 VYLVMELMDANLCQVIHM--ELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKS 161 Query: 203 DCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIF 382 DC LKI DFGLAR A + T YV TR+YRAPE+ Y +DIWS+GCI Sbjct: 162 DCTLKILDFGLART----ACTNFMMTPYVVTRYYRAPEVI--LGMGYKENVDIWSVGCIM 215 Query: 383 AELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYLKLHAK 535 EL+ G +F G + + Q + + + LGTPS+E + +++ R Y++ K Sbjct: 216 GELVKGCVIFQGTDHIDQWNKVIEQLGTPSAEFMKKLQ-PTVRNYVENRPK 265
>MK09_HUMAN (P45984) Mitogen-activated protein kinase 9 (EC 2.7.11.24)| (Stress-activated protein kinase JNK2) (c-Jun N-terminal kinase 2) (JNK-55) Length = 424 Score = 130 bits (328), Expect = 2e-30 Identities = 71/171 (41%), Positives = 104/171 (60%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANA 202 +Y+V ELM+++L QVI +L E + LYQ+L +K++H A + HRDLKP NI+ + Sbjct: 104 VYLVMELMDANLCQVIHM--ELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKS 161 Query: 203 DCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIF 382 DC LKI DFGLAR A + T YV TR+YRAPE+ Y +DIWS+GCI Sbjct: 162 DCTLKILDFGLART----ACTNFMMTPYVVTRYYRAPEVI--LGMGYKENVDIWSVGCIM 215 Query: 383 AELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYLKLHAK 535 EL+ G +F G + + Q + + + LGTPS+E + +++ R Y++ K Sbjct: 216 GELVKGCVIFQGTDHIDQWNKVIEQLGTPSAEFMKKLQ-PTVRNYVENRPK 265
>PCTK1_HUMAN (Q00536) Serine/threonine-protein kinase PCTAIRE-1 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 1) Length = 496 Score = 130 bits (328), Expect = 2e-30 Identities = 76/170 (44%), Positives = 103/170 (60%), Gaps = 3/170 (1%) Frame = +2 Query: 17 KXIYVVFELMESDLHQVIRANDDLTAEH-YQFFLYQLLRALKYIHGANVFHRDLKPKNIL 193 K + +VFE ++ DL Q + ++ H + FL+QLLR L Y H V HRDLKP+N+L Sbjct: 234 KSLTLVFEYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLL 293 Query: 194 ANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPE-LCGSFFSKYTPAIDIWSI 370 N +LK+ DFGLAR P+ + ++ V T WYR P+ L GS + Y+ ID+W + Sbjct: 294 INERGELKLADFGLARAK--SIPTKTY-SNEVVTLWYRPPDILLGS--TDYSTQIDMWGV 348 Query: 371 GCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRI-RNEKARRY 517 GCIF E+ TGRPLFPG V QL I +LGTP+ ET I NE+ + Y Sbjct: 349 GCIFYEMATGRPLFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKTY 398
>CCRK_MOUSE (Q9JHU3) Cell cycle-related kinase (EC 2.7.11.22)| (Cyclin-kinase-activating kinase p42) (CDK-activating kinase p42) (CAK-kinase p42) (CDK-related protein kinase PNQLARE) Length = 346 Score = 130 bits (327), Expect(2) = 3e-30 Identities = 70/149 (46%), Positives = 92/149 (61%), Gaps = 1/149 (0%) Frame = +2 Query: 29 VVFELMESDLHQVIR-ANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANAD 205 + FE M SDL +V+R A L + +L LL+ + + H N+ HRDLKP N+L +A Sbjct: 79 LAFEFMLSDLAEVVRHAQRPLAPAQVKSYLQMLLKGVAFCHANNIVHRDLKPANLLISAS 138 Query: 206 CKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIFA 385 +LKI DFGLARV D +T VATRWYRAPEL +Y +D+W++GCI Sbjct: 139 GQLKIADFGLARVFSPDGGR--LYTHQVATRWYRAPELLYGA-RQYDQGVDLWAVGCIMG 195 Query: 386 ELLTGRPLFPGKNVVHQLDIITDLLGTPS 472 ELL G PLFPG+N + QL + +LGTPS Sbjct: 196 ELLNGSPLFPGENDIEQLCCVLRILGTPS 224 Score = 21.2 bits (43), Expect(2) = 3e-30 Identities = 9/28 (32%), Positives = 14/28 (50%) Frame = +3 Query: 498 TRRPGGTLSCMRKKHPVPLTQKFPNADP 581 T P +++ PVPL + P+A P Sbjct: 232 TELPDYNKISFKEQAPVPLEEVLPDASP 259
>CCRK_RAT (Q4KM34) Cell cycle-related kinase (EC 2.7.11.22)| Length = 346 Score = 130 bits (327), Expect = 3e-30 Identities = 70/149 (46%), Positives = 92/149 (61%), Gaps = 1/149 (0%) Frame = +2 Query: 29 VVFELMESDLHQVIR-ANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANAD 205 + FE M SDL +V+R A L + +L LL+ + + H N+ HRDLKP N+L +A Sbjct: 79 LAFEFMLSDLAEVVRHAQRPLAPAQVKSYLQMLLKGVAFCHANNIVHRDLKPANLLISAS 138 Query: 206 CKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIFA 385 +LKI DFGLARV D +T VATRWYRAPEL +Y +D+W++GCI Sbjct: 139 GQLKIADFGLARVFSPDGGR--LYTHQVATRWYRAPELLYGA-RQYDQGVDLWAVGCIMG 195 Query: 386 ELLTGRPLFPGKNVVHQLDIITDLLGTPS 472 ELL G PLFPG+N + QL + +LGTPS Sbjct: 196 ELLNGSPLFPGENDIEQLCCVLRILGTPS 224
>MK04_RAT (Q63454) Mitogen-activated protein kinase 4 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 4) (ERK-4) (MAP kinase isoform p63) (p63-MAPK) (MNK2) (Fragment) Length = 274 Score = 130 bits (327), Expect = 3e-30 Identities = 70/146 (47%), Positives = 96/146 (65%), Gaps = 1/146 (0%) Frame = +2 Query: 26 YVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNI-LANA 202 Y+V E ME+DL ++ LT EH + F+YQLLR LKYIH ANV HRDLKP NI ++ Sbjct: 76 YIVQEYMETDLACLLEQGT-LTEEHAKLFMYQLLRGLKYIHSANVLHRDLKPANIFISTE 134 Query: 203 DCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIF 382 D LKI DFGLAR++ + ++ + T+WYR+P L S + YT AID+W+ GCI Sbjct: 135 DLVLKIGDFGLARIADQHYSHKGYLSEGLVTKWYRSPRLLLS-PNNYTKAIDMWAAGCIL 193 Query: 383 AELLTGRPLFPGKNVVHQLDIITDLL 460 AE+LTG+ LF G + + Q+ +I D + Sbjct: 194 AEMLTGKMLFAGAHELEQMQLILDTI 219
>PCTK3_PONPY (Q5RD01) Serine/threonine-protein kinase PCTAIRE-3 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 3) Length = 472 Score = 130 bits (326), Expect = 4e-30 Identities = 75/176 (42%), Positives = 105/176 (59%), Gaps = 8/176 (4%) Frame = +2 Query: 17 KXIYVVFELMESDLHQVIRANDDLTAEH-YQFFLYQLLRALKYIHGANVFHRDLKPKNIL 193 + + +VFE ++SDL Q + +L + H + F++QLLR L Y H + HRDLKP+N+L Sbjct: 211 RSLTLVFEYLDSDLKQYLDHCGNLMSMHNVKIFMFQLLRGLAYCHHRKILHRDLKPQNLL 270 Query: 194 ANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPE-LCGSFFSKYTPAIDIWSI 370 N +LK+ DFGLAR P+ + ++ V T WYR P+ L GS ++Y+ ID+W + Sbjct: 271 INERGELKLADFGLARAK--SVPTKTY-SNEVVTLWYRPPDVLLGS--TEYSTPIDMWGV 325 Query: 371 GCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSET------LSRIRNEKARRYL 520 GCI E+ TGRPLFPG V +L +I LLGTP+ ET S R RYL Sbjct: 326 GCIHYEMATGRPLFPGSTVKEELHLIFRLLGTPTEETWPGVTAFSEFRTYSFPRYL 381
>CDC2H_THEAN (Q26671) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 298 Score = 130 bits (326), Expect = 4e-30 Identities = 73/165 (44%), Positives = 103/165 (62%), Gaps = 2/165 (1%) Frame = +2 Query: 11 NSKXIYVVFELMESDLHQVIRANDD-LTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKN 187 + K + +VFE ++ DL +++ A D L + FLYQ+LR + Y H + HRDLKP+N Sbjct: 71 SEKCLTLVFEYLDQDLKKLLDACDGGLEPTTAKSFLYQILRGISYCHDHRILHRDLKPQN 130 Query: 188 ILANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPE-LCGSFFSKYTPAIDIW 364 +L N + LK+ DFGLAR S +T V T WYRAP+ L GS KY+ A+DIW Sbjct: 131 LLINREGVLKLADFGLARAFAIPVRS---YTHEVVTLWYRAPDVLMGS--KKYSTAVDIW 185 Query: 365 SIGCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRN 499 S+GCIFAE++ G PLFPG + QL I +LGTP+ ++ ++ N Sbjct: 186 SVGCIFAEMINGVPLFPGISEQDQLKRIFKILGTPNVDSWPQVVN 230
>MK06_RAT (P27704) Mitogen-activated protein kinase 6 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 3) (ERK-3) (p55-MAPK) Length = 720 Score = 129 bits (325), Expect = 5e-30 Identities = 70/145 (48%), Positives = 93/145 (64%), Gaps = 1/145 (0%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANA 202 +Y+V E ME+DL V+ L EH + F+YQLLR LKYIH ANV HRDLKP N+ N Sbjct: 104 VYIVQEYMETDLANVLEQGP-LLEEHARLFMYQLLRGLKYIHSANVLHRDLKPANLFINT 162 Query: 203 -DCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCI 379 D LKI DFGLAR+ ++ + T+WYR+P L S + YT AID+W+ GCI Sbjct: 163 EDLVLKIGDFGLARIMDPHYSHKGHLSEGLVTKWYRSPRLLLS-PNNYTKAIDMWAAGCI 221 Query: 380 FAELLTGRPLFPGKNVVHQLDIITD 454 FAE+LTG+ LF G + + Q+ +I + Sbjct: 222 FAEMLTGKTLFAGAHELEQMQLILE 246
>MK06_HUMAN (Q16659) Mitogen-activated protein kinase 6 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 3) (ERK-3) (MAP kinase isoform p97) (p97-MAPK) Length = 721 Score = 129 bits (325), Expect = 5e-30 Identities = 70/145 (48%), Positives = 93/145 (64%), Gaps = 1/145 (0%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANA 202 +Y+V E ME+DL V+ L EH + F+YQLLR LKYIH ANV HRDLKP N+ N Sbjct: 104 VYIVQEYMETDLANVLEQGP-LLEEHARLFMYQLLRGLKYIHSANVLHRDLKPANLFINT 162 Query: 203 -DCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCI 379 D LKI DFGLAR+ ++ + T+WYR+P L S + YT AID+W+ GCI Sbjct: 163 EDLVLKIGDFGLARIMDPHYSHKGHLSEGLVTKWYRSPRLLLS-PNNYTKAIDMWAAGCI 221 Query: 380 FAELLTGRPLFPGKNVVHQLDIITD 454 FAE+LTG+ LF G + + Q+ +I + Sbjct: 222 FAEMLTGKTLFAGAHELEQMQLILE 246
>PCTK3_HUMAN (Q07002) Serine/threonine-protein kinase PCTAIRE-3 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 3) Length = 472 Score = 129 bits (324), Expect = 6e-30 Identities = 70/157 (44%), Positives = 100/157 (63%), Gaps = 2/157 (1%) Frame = +2 Query: 17 KXIYVVFELMESDLHQVIRANDDLTAEH-YQFFLYQLLRALKYIHGANVFHRDLKPKNIL 193 + + +VFE ++SDL Q + +L + H + F++QLLR L Y H + HRDLKP+N+L Sbjct: 211 RSLTLVFEYLDSDLKQYLDHCGNLMSMHNVKIFMFQLLRGLAYCHHRKILHRDLKPQNLL 270 Query: 194 ANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPE-LCGSFFSKYTPAIDIWSI 370 N +LK+ DFGLAR P+ + ++ V T WYR P+ L GS ++Y+ ID+W + Sbjct: 271 INERGELKLADFGLARAK--SVPTKTY-SNEVVTLWYRPPDVLLGS--TEYSTPIDMWGV 325 Query: 371 GCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSET 481 GCI E+ TGRPLFPG V +L +I LLGTP+ ET Sbjct: 326 GCIHYEMATGRPLFPGSTVKEELHLIFRLLGTPTEET 362
>MK04_HUMAN (P31152) Mitogen-activated protein kinase 4 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 4) (ERK-4) (MAP kinase isoform p63) (p63-MAPK) Length = 557 Score = 129 bits (324), Expect = 6e-30 Identities = 75/168 (44%), Positives = 102/168 (60%), Gaps = 1/168 (0%) Frame = +2 Query: 26 YVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNI-LANA 202 Y+V E ME+DL +++ L EH + F+YQLLR LKYIH ANV HRDLKP NI ++ Sbjct: 102 YIVQEYMETDLARLLEQGT-LAEEHAKLFMYQLLRGLKYIHSANVLHRDLKPANIFISTE 160 Query: 203 DCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIF 382 D LKI DFGLAR+ + ++ + T+WYR+P L S + YT AID+W+ GCI Sbjct: 161 DLVLKIGDFGLARIVDQHYSHKGYLSEGLVTKWYRSPRLLLS-PNNYTKAIDMWAAGCIL 219 Query: 383 AELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRYLKL 526 AE+LTGR LF G + + Q+ +I ET+ IR E L++ Sbjct: 220 AEMLTGRMLFAGAHELEQMQLIL--------ETIPVIREEDKDELLRV 259
>CDC2H_PLABA (Q4Z6R1) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 288 Score = 128 bits (321), Expect = 1e-29 Identities = 75/156 (48%), Positives = 98/156 (62%), Gaps = 2/156 (1%) Frame = +2 Query: 17 KXIYVVFELMESDLHQVIRANDD-LTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNIL 193 K + +VFE ++ DL ++I D L + + FL QLL + Y H V HRDLKP+N+L Sbjct: 73 KRLILVFEHLDQDLKKLIDVCDGGLESVTAKSFLLQLLNGIAYCHEHRVLHRDLKPQNLL 132 Query: 194 ANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPE-LCGSFFSKYTPAIDIWSI 370 N + +LKI DFGLAR A +T V T WYRAP+ L GS KY+ IDIWS+ Sbjct: 133 INREGELKIADFGLARAFGIPARR---YTHEVVTLWYRAPDILMGS--KKYSTPIDIWSV 187 Query: 371 GCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSE 478 GCIFAE++ GRPLFPG + QL I +LGTP+S+ Sbjct: 188 GCIFAEMVNGRPLFPGASETDQLMRIFKILGTPNSQ 223
>MK04_MOUSE (Q6P5G0) Mitogen-activated protein kinase 4 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 4) (ERK-4) Length = 583 Score = 128 bits (321), Expect = 1e-29 Identities = 69/146 (47%), Positives = 95/146 (65%), Gaps = 1/146 (0%) Frame = +2 Query: 26 YVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNI-LANA 202 Y+V E ME+DL ++ LT +H + F+YQLLR LKYIH ANV HRDLKP NI ++ Sbjct: 102 YIVQEYMETDLACLLEQGT-LTEDHAKLFMYQLLRGLKYIHSANVLHRDLKPANIFISTE 160 Query: 203 DCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIF 382 D LKI DFGLAR+ + ++ + T+WYR+P L S + YT AID+W+ GCI Sbjct: 161 DLVLKIGDFGLARIVDQHYSHKGYLSEGLVTKWYRSPRLLLS-PNNYTKAIDMWAAGCIL 219 Query: 383 AELLTGRPLFPGKNVVHQLDIITDLL 460 AE+LTG+ LF G + + Q+ +I D + Sbjct: 220 AEMLTGKMLFAGAHELEQMQLILDTI 245
>PCTK1_RAT (Q63686) Serine/threonine-protein kinase PCTAIRE-1 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 1) Length = 496 Score = 128 bits (321), Expect = 1e-29 Identities = 78/189 (41%), Positives = 107/189 (56%), Gaps = 12/189 (6%) Frame = +2 Query: 17 KXIYVVFELMESDLHQVIR-ANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNIL 193 K + +VFE ++ DL Q + + + + + FL+QLLR L Y H V HRDLKP+N+L Sbjct: 234 KSLTLVFEYLDKDLKQYLDDCGNVINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLL 293 Query: 194 ANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPE-LCGSFFSKYTPAIDIWSI 370 N +LK+ DFGLA P+ + ++ V T WYR P+ L GS + Y+ ID+W + Sbjct: 294 INERGELKLADFGLAYAK--SIPTKTY-SNEVVTLWYRPPDILLGS--TDYSGQIDMWGV 348 Query: 371 GCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRI-RNEKARRY---------L 520 GCIF E+ TGRPLFPG V QL I +LGTP+ +T I NE+ R Y L Sbjct: 349 GCIFYEMATGRPLFPGSTVEEQLHFIFRILGTPTEDTWPGILSNEEFRTYNYPKYRAEAL 408 Query: 521 KLHAKKTSC 547 HA + C Sbjct: 409 LRHAPRLEC 417
>CDC2H_PLAYO (Q7RM49) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 289 Score = 127 bits (320), Expect = 2e-29 Identities = 75/156 (48%), Positives = 98/156 (62%), Gaps = 2/156 (1%) Frame = +2 Query: 17 KXIYVVFELMESDLHQVIRANDD-LTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNIL 193 K + +VFE ++ DL ++I D L + + FL QLL + Y H V HRDLKP+N+L Sbjct: 74 KRLILVFEHLDQDLKKLIDVCDGGLESVTAKSFLLQLLNGIAYCHEHRVLHRDLKPQNLL 133 Query: 194 ANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPE-LCGSFFSKYTPAIDIWSI 370 N + +LKI DFGLAR A +T V T WYRAP+ L GS KY+ IDIWS+ Sbjct: 134 INREGELKIADFGLARAFGIPARR---YTHEVVTLWYRAPDILMGS--KKYSTPIDIWSV 188 Query: 371 GCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSE 478 GCIFAE++ GRPLFPG + QL I +LGTP+S+ Sbjct: 189 GCIFAEMVNGRPLFPGVSETDQLMRIFKILGTPNSQ 224
>MOK_MOUSE (Q9WVS4) MAPK/MAK/MRK overlapping kinase (EC 2.7.11.22) (MOK| protein kinase) Length = 420 Score = 127 bits (320), Expect = 2e-29 Identities = 64/169 (37%), Positives = 107/169 (63%), Gaps = 1/169 (0%) Frame = +2 Query: 14 SKXIYVVFELMESDLHQVIRAN-DDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNI 190 S + ++ ELM+ +++++IR L+ + ++YQL ++L ++H +FHRD+KP+NI Sbjct: 75 SGSLALICELMDMNIYELIRGRRHPLSEKKIMLYMYQLCKSLDHMHRNGIFHRDVKPENI 134 Query: 191 LANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSI 370 L D LK+ DFG R ++ P +T+Y++TRWYRAPE C YT +D+WS Sbjct: 135 LVKQDV-LKLGDFGSCRSVYSKQP----YTEYISTRWYRAPE-CLLTDGFYTYKMDLWSA 188 Query: 371 GCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRY 517 GC+F E+ + +PLFPG N + Q+ I D++GTP +TL++ + +A + Sbjct: 189 GCVFYEIASLQPLFPGVNELDQISKIHDVIGTPCQKTLTKFKQSRAMSF 237
>PCTK3_RAT (O35832) Serine/threonine-protein kinase PCTAIRE-3 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 3) Length = 451 Score = 127 bits (320), Expect = 2e-29 Identities = 76/190 (40%), Positives = 110/190 (57%), Gaps = 8/190 (4%) Frame = +2 Query: 17 KXIYVVFELMESDLHQVIRANDDLTAEH-YQFFLYQLLRALKYIHGANVFHRDLKPKNIL 193 + + +VFE ++SDL Q + +L H + F++QLLR L Y H + HRDLKP+N+L Sbjct: 190 RSLTLVFEYLDSDLKQYLDHCGNLMNMHNVKIFMFQLLRGLAYCHRRKILHRDLKPQNLL 249 Query: 194 ANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPE-LCGSFFSKYTPAIDIWSI 370 N +LK+ DFGLAR P+ + ++ V T WYR P+ L GS ++Y+ ID+W + Sbjct: 250 INERGELKLADFGLARAK--SVPTKTY-SNEVVTLWYRPPDVLLGS--TEYSTPIDMWGV 304 Query: 371 GCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSE------TLSRIRNEKARRYLKLHA 532 GCI E+ TG+PLFPG V +L +I LLGTP+ E ++S R RYL Sbjct: 305 GCILYEMATGKPLFPGSTVKEELHLIFRLLGTPTEESWPGVTSISEFRAYNFPRYLPQPL 364 Query: 533 KKTSCALDSE 562 + LD+E Sbjct: 365 LSHAPRLDTE 374
>PCTK3_MOUSE (Q04899) Serine/threonine-protein kinase PCTAIRE-3 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 3) Length = 451 Score = 127 bits (320), Expect = 2e-29 Identities = 76/190 (40%), Positives = 110/190 (57%), Gaps = 8/190 (4%) Frame = +2 Query: 17 KXIYVVFELMESDLHQVIRANDDLTAEH-YQFFLYQLLRALKYIHGANVFHRDLKPKNIL 193 + + +VFE ++SDL Q + +L H + F++QLLR L Y H + HRDLKP+N+L Sbjct: 190 RSLTLVFEYLDSDLKQYLDHCGNLMNMHNVKIFMFQLLRGLAYCHHRKILHRDLKPQNLL 249 Query: 194 ANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPE-LCGSFFSKYTPAIDIWSI 370 N +LK+ DFGLAR P+ + ++ V T WYR P+ L GS ++Y+ ID+W + Sbjct: 250 INERGELKLADFGLARAK--SVPTKTY-SNEVVTLWYRPPDVLLGS--TEYSTPIDMWGV 304 Query: 371 GCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSE------TLSRIRNEKARRYLKLHA 532 GCI E+ TG+PLFPG V +L +I LLGTP+ E ++S R RYL Sbjct: 305 GCILYEMATGKPLFPGSTVKEELHLIFRLLGTPTEESWPGVTSISEFRAYNFPRYLPQPL 364 Query: 533 KKTSCALDSE 562 + LD+E Sbjct: 365 LSHAPRLDTE 374
>CDC2H_PLACH (Q4Y4B1) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 288 Score = 127 bits (319), Expect = 2e-29 Identities = 75/156 (48%), Positives = 98/156 (62%), Gaps = 2/156 (1%) Frame = +2 Query: 17 KXIYVVFELMESDLHQVIRANDD-LTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNIL 193 K + +VFE ++ DL ++I D L + + FL QLL + Y H V HRDLKP+N+L Sbjct: 73 KRLILVFEHLDQDLKKLIDVCDGGLESVTAKSFLLQLLNGIAYCHEHRVLHRDLKPQNLL 132 Query: 194 ANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPE-LCGSFFSKYTPAIDIWSI 370 N + +LKI DFGLAR A +T V T WYRAP+ L GS KY+ IDIWS+ Sbjct: 133 INREGELKIADFGLARAFGIPARR---YTHEVVTLWYRAPDILMGS--KKYSTPIDIWSV 187 Query: 371 GCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSE 478 GCIFAE++ GRPLFPG + QL I +LGTP+S+ Sbjct: 188 GCIFAEMVNGRPLFPGVSDTDQLMRIFKILGTPNSQ 223
>PHO85_YARLI (Q6C7U8) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 294 Score = 127 bits (319), Expect = 2e-29 Identities = 74/159 (46%), Positives = 98/159 (61%), Gaps = 4/159 (2%) Frame = +2 Query: 29 VVFELMESDLHQVIRANDD---LTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILAN 199 +VFE M+ DL + + N + L + ++F+YQLLR + + H V HRDLKP+N+L N Sbjct: 80 LVFEYMDKDLKKFMDTNGNKGALETKQVKWFMYQLLRGILFCHDNRVLHRDLKPQNLLIN 139 Query: 200 ADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPE-LCGSFFSKYTPAIDIWSIGC 376 A +LK+ DFGLAR P F ++ V T WYRAP+ L GS Y+ +IDIWS GC Sbjct: 140 AKGQLKLADFGLARAF--GIPVNTF-SNEVVTLWYRAPDVLLGS--RTYSTSIDIWSAGC 194 Query: 377 IFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRI 493 I AE+ TGRPLFPG + QL I L+GTP+ T I Sbjct: 195 IMAEMFTGRPLFPGSSNDDQLQHIFKLMGTPNESTWPNI 233
>BUR1_NEUCR (Q871M9) Serine/threonine-protein kinase bur-1 (EC 2.7.11.22) (EC| 2.7.11.23) Length = 545 Score = 127 bits (318), Expect = 3e-29 Identities = 67/163 (41%), Positives = 96/163 (58%), Gaps = 9/163 (5%) Frame = +2 Query: 23 IYVVFELMESDLHQVI-RANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILAN 199 +Y+V M+ DL ++ + T + +L QLL LKY+H ++ HRD+K N+L N Sbjct: 107 VYMVTPYMDHDLSGLLDNPSVRFTEPQVKCYLLQLLEGLKYLHANHILHRDMKAANLLIN 166 Query: 200 ADCKLKICDFGLARVSFNDAPSA--------IFWTDYVATRWYRAPELCGSFFSKYTPAI 355 L+I DFGLAR D P +T V TRWYR PEL +YT AI Sbjct: 167 NKGVLQIADFGLARHYEGDIPQPGKGSGEGKRDYTSLVVTRWYRPPELL-MHLKRYTTAI 225 Query: 356 DIWSIGCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETL 484 D+W +GC+FAE+L G+P+ G++ +HQL+++ DL GTPS ET+ Sbjct: 226 DMWGVGCVFAEMLEGKPVLQGESDLHQLELVWDLCGTPSEETM 268
>MOK_HUMAN (Q9UQ07) MAPK/MAK/MRK overlapping kinase (EC 2.7.11.22) (MOK| protein kinase) (Renal tumor antigen 1) (RAGE-1) Length = 419 Score = 126 bits (317), Expect = 4e-29 Identities = 64/169 (37%), Positives = 107/169 (63%), Gaps = 1/169 (0%) Frame = +2 Query: 14 SKXIYVVFELMESDLHQVIRAND-DLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNI 190 S + ++ ELM+ +++++IR L+ + ++YQL ++L +IH +FHRD+KP+NI Sbjct: 75 SGSLALICELMDMNIYELIRGRRYPLSEKKIMHYMYQLCKSLDHIHRNGIFHRDVKPENI 134 Query: 191 LANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSI 370 L D LK+ DFG R ++ P +T+Y++TRWYRAPE C YT +D+WS Sbjct: 135 LIKQDV-LKLGDFGSCRSVYSKQP----YTEYISTRWYRAPE-CLLTDGFYTYKMDLWSA 188 Query: 371 GCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRNEKARRY 517 GC+F E+ + +PLFPG N + Q+ I D++GTP+ + L++ + +A + Sbjct: 189 GCVFYEIASLQPLFPGVNELDQISKIHDVIGTPAQKILTKFKQSRAMNF 237
>CDK3_HUMAN (Q00526) Cell division protein kinase 3 (EC 2.7.11.22)| Length = 305 Score = 126 bits (316), Expect = 5e-29 Identities = 72/160 (45%), Positives = 99/160 (61%), Gaps = 3/160 (1%) Frame = +2 Query: 11 NSKXIYVVFELMESDLHQVIRAN--DDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPK 184 N + +Y+VFE + DL + + + +L + +L+QLL+ + + H V HRDLKP+ Sbjct: 72 NERKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQLLQGVSFCHSHRVIHRDLKPQ 131 Query: 185 NILANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPE-LCGSFFSKYTPAIDI 361 N+L N +K+ DFGLAR P + T V T WYRAPE L GS F YT A+DI Sbjct: 132 NLLINELGAIKLADFGLARAF--GVPLRTY-THEVVTLWYRAPEILLGSKF--YTTAVDI 186 Query: 362 WSIGCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSET 481 WSIGCIFAE++T + LFPG + + QL I +LGTPS +T Sbjct: 187 WSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDT 226
>ICK_MOUSE (Q9JKV2) Serine/threonine-protein kinase ICK (EC 2.7.11.22)| (Intestinal cell kinase) (mICK) (MAK-related kinase) (MRK) Length = 629 Score = 125 bits (314), Expect = 9e-29 Identities = 67/150 (44%), Positives = 96/150 (64%), Gaps = 1/150 (0%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRANDDLTAEH-YQFFLYQLLRALKYIHGANVFHRDLKPKNILAN 199 +Y +FE M+ +L+Q+I+ + L E + +YQ+L+ L +IH FHRDLKP+N+L Sbjct: 75 LYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKHGFFHRDLKPENLLCM 134 Query: 200 ADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCI 379 +KI DFGLAR + P +TDYV+TRWYRAPE+ + Y+ IDIW++GCI Sbjct: 135 GPELVKIADFGLAREIRSRPP----YTDYVSTRWYRAPEVLLRS-TNYSSPIDIWAVGCI 189 Query: 380 FAELLTGRPLFPGKNVVHQLDIITDLLGTP 469 AE+ T RPLFPG + + + I +LGTP Sbjct: 190 MAEVYTLRPLFPGASEIDTIFKICQVLGTP 219
>ICK_HUMAN (Q9UPZ9) Serine/threonine-protein kinase ICK (EC 2.7.11.22)| (Intestinal cell kinase) (hICK) (MAK-related kinase) (MRK) (Laryngeal cancer kinase 2) (LCK2) Length = 632 Score = 125 bits (314), Expect = 9e-29 Identities = 66/150 (44%), Positives = 96/150 (64%), Gaps = 1/150 (0%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRANDDLTAEH-YQFFLYQLLRALKYIHGANVFHRDLKPKNILAN 199 +Y +FE M+ +L+Q+I+ + L E + +YQ+L+ L +IH FHRDLKP+N+L Sbjct: 75 LYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKHGFFHRDLKPENLLCM 134 Query: 200 ADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCI 379 +KI DFGLAR + P +TDYV+TRWYRAPE+ + Y+ ID+W++GCI Sbjct: 135 GPELVKIADFGLAREIRSKPP----YTDYVSTRWYRAPEVLLRS-TNYSSPIDVWAVGCI 189 Query: 380 FAELLTGRPLFPGKNVVHQLDIITDLLGTP 469 AE+ T RPLFPG + + + I +LGTP Sbjct: 190 MAEVYTLRPLFPGASEIDTIFKICQVLGTP 219
>ICK_RAT (Q62726) Serine/threonine-protein kinase ICK (EC 2.7.11.22)| (Intestinal cell kinase) (MAK-related kinase) (MRK) Length = 629 Score = 125 bits (313), Expect = 1e-28 Identities = 66/150 (44%), Positives = 96/150 (64%), Gaps = 1/150 (0%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRANDDLTAEH-YQFFLYQLLRALKYIHGANVFHRDLKPKNILAN 199 +Y +FE M+ +L+Q+I+ + L E + +YQ+L+ L +IH FHRDLKP+N+L Sbjct: 75 LYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKHGFFHRDLKPENLLCM 134 Query: 200 ADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCI 379 +KI DFGLAR + P +TDYV+TRWYRAPE+ + Y+ ID+W++GCI Sbjct: 135 GPELVKIADFGLAREIRSRPP----YTDYVSTRWYRAPEVLLRS-TNYSSPIDVWAVGCI 189 Query: 380 FAELLTGRPLFPGKNVVHQLDIITDLLGTP 469 AE+ T RPLFPG + + + I +LGTP Sbjct: 190 MAEVYTLRPLFPGASEIDTIFKICQVLGTP 219
>CDC2H_PLAVI (Q9XZD6) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (Pvcrk2) Length = 288 Score = 125 bits (313), Expect = 1e-28 Identities = 73/156 (46%), Positives = 97/156 (62%), Gaps = 2/156 (1%) Frame = +2 Query: 17 KXIYVVFELMESDLHQVIRANDD-LTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNIL 193 K + +VFE ++ DL +++ D L + + FL QLL + Y H V HRDLKP+N+L Sbjct: 73 KRLILVFEHLDQDLKKLLDVCDGGLESVTAKSFLLQLLSGIAYCHEHRVLHRDLKPQNLL 132 Query: 194 ANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPE-LCGSFFSKYTPAIDIWSI 370 N + +LKI DFGLAR +T V T WYRAP+ L GS KY+ ID+WS+ Sbjct: 133 INREGELKIADFGLARAFGIPVRK---YTHEVVTLWYRAPDILMGS--KKYSTPIDMWSV 187 Query: 371 GCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSE 478 GCIFAE++ GRPLFPG + QL I +LGTP+SE Sbjct: 188 GCIFAEMVNGRPLFPGVSETDQLMRIFRILGTPNSE 223
>CDKL4_MOUSE (Q3TZA2) Cyclin-dependent kinase-like 4 (EC 2.7.11.22)| Length = 342 Score = 125 bits (313), Expect = 1e-28 Identities = 68/151 (45%), Positives = 97/151 (64%), Gaps = 2/151 (1%) Frame = +2 Query: 17 KXIYVVFELMESDLHQVIRANDDLTAEHY-QFFLYQLLRALKYIHGANVFHRDLKPKNIL 193 + +++VFE + L + N + ++ + L+Q L+AL + H N HRD+KP+NIL Sbjct: 74 RKMHLVFEYCDHTLLNELERNPNGVSDGVIKSVLWQTLQALNFCHKHNCIHRDVKPENIL 133 Query: 194 ANADCKLKICDFGLARVSF-NDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSI 370 +KICDFG AR+ DA +TDYVATRWYRAPEL +KY ++D+W++ Sbjct: 134 ITKQGMIKICDFGFARILIPGDA-----YTDYVATRWYRAPELLVGD-TKYGSSVDVWAV 187 Query: 371 GCIFAELLTGRPLFPGKNVVHQLDIITDLLG 463 GC+FAELLTG+PL+PGK+ V QL +I LG Sbjct: 188 GCVFAELLTGQPLWPGKSDVDQLYLIIRTLG 218
>CDK5_XENLA (P51166) Cell division protein kinase 5 (EC 2.7.11.22) (Neuronal| cyclin-dependent kinase 5) Length = 292 Score = 124 bits (311), Expect = 2e-28 Identities = 74/159 (46%), Positives = 99/159 (62%), Gaps = 3/159 (1%) Frame = +2 Query: 11 NSKXIYVVFELMESDLHQVIRA-NDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKN 187 + K + +VFE + DL + + N DL E + F+YQLL+ L + H NV HRDLKP+N Sbjct: 72 SDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFMYQLLKGLAFCHSRNVLHRDLKPQN 131 Query: 188 ILANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSK-YTPAIDIW 364 +L N + +LK+ DFGLAR P + + V T WYR P++ F +K Y+ +ID+W Sbjct: 132 LLINRNGELKLADFGLARAF--GIPVRCYSAE-VVTLWYRPPDVL--FGAKLYSTSIDMW 186 Query: 365 SIGCIFAELL-TGRPLFPGKNVVHQLDIITDLLGTPSSE 478 S GCIFAEL GRPLFPG +V QL I LLGTP+ E Sbjct: 187 SAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEE 225
>CDC2H_PLAKH (O96821) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 288 Score = 124 bits (311), Expect = 2e-28 Identities = 73/155 (47%), Positives = 96/155 (61%), Gaps = 2/155 (1%) Frame = +2 Query: 17 KXIYVVFELMESDLHQVIRANDD-LTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNIL 193 K + +VFE ++ DL +++ D L + + FL QLL + Y H V HRDLKP+N+L Sbjct: 73 KRLILVFEHLDQDLKKLLDVCDGGLESVTAKSFLLQLLSGIAYCHEHRVLHRDLKPQNLL 132 Query: 194 ANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPE-LCGSFFSKYTPAIDIWSI 370 N + +LKI DFGLAR +T V T WYRAP+ L GS KY+ IDIWS+ Sbjct: 133 INREGELKIADFGLARAFGIPVRK---YTHEVVTLWYRAPDILMGS--KKYSTPIDIWSV 187 Query: 371 GCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSS 475 GCIFAE++ GRPLFPG + QL I +LGTP+S Sbjct: 188 GCIFAEMVNGRPLFPGVSETDQLMRIFRILGTPNS 222
>CDK5_BOVIN (Q02399) Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein| kinase II catalytic subunit) (TPKII catalytic subunit) (Proline-directed protein kinase 33 kDa subunit) (PDPK) Length = 292 Score = 124 bits (310), Expect = 3e-28 Identities = 74/159 (46%), Positives = 100/159 (62%), Gaps = 3/159 (1%) Frame = +2 Query: 11 NSKXIYVVFELMESDLHQVIRA-NDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKN 187 + K + +VFE + DL + + N DL E + FL+QLL+ L + H NV HRDLKP+N Sbjct: 72 SDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSRNVLHRDLKPQN 131 Query: 188 ILANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSK-YTPAIDIW 364 +L N + +LK+ DFGLAR P + + V T WYR+P++ F +K Y+ +ID+W Sbjct: 132 LLINRNGELKLADFGLARAF--GIPVRCYSAE-VVTLWYRSPDVL--FGAKLYSTSIDMW 186 Query: 365 SIGCIFAELL-TGRPLFPGKNVVHQLDIITDLLGTPSSE 478 S GCIFAEL GRPLFPG +V QL I LLGTP+ E Sbjct: 187 SAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEE 225
>MAK_MOUSE (Q04859) Serine/threonine-protein kinase MAK (EC 2.7.11.22) (Male| germ cell-associated kinase) (Protein kinase RCK) Length = 622 Score = 123 bits (309), Expect = 3e-28 Identities = 67/150 (44%), Positives = 96/150 (64%), Gaps = 1/150 (0%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRANDDLTAEHY-QFFLYQLLRALKYIHGANVFHRDLKPKNILAN 199 +Y VFE M+ +L+Q+++ + L E + +YQ+L+ L +IH FHRD+KP+N+L Sbjct: 75 LYFVFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHGFFHRDMKPENLLCM 134 Query: 200 ADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCI 379 +KI DFGLAR + P +TDYV+TRWYRAPE+ S Y+ ID+W++G I Sbjct: 135 GPELVKIADFGLARELRSQPP----YTDYVSTRWYRAPEVLLRS-SVYSSPIDVWAVGSI 189 Query: 380 FAELLTGRPLFPGKNVVHQLDIITDLLGTP 469 AEL T RPLFPG + V ++ I +LGTP Sbjct: 190 MAELYTFRPLFPGTSEVDEIFKICQVLGTP 219
>CDK5_MOUSE (P49615) Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein| kinase II catalytic subunit) (TPKII catalytic subunit) (Serine/threonine-protein kinase PSSALRE) (CRK6) Length = 292 Score = 123 bits (308), Expect = 4e-28 Identities = 74/159 (46%), Positives = 99/159 (62%), Gaps = 3/159 (1%) Frame = +2 Query: 11 NSKXIYVVFELMESDLHQVIRA-NDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKN 187 + K + +VFE + DL + + N DL E + FL+QLL+ L + H NV HRDLKP+N Sbjct: 72 SDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSRNVLHRDLKPQN 131 Query: 188 ILANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSK-YTPAIDIW 364 +L N + +LK+ DFGLAR P + + V T WYR P++ F +K Y+ +ID+W Sbjct: 132 LLINRNGELKLADFGLARAF--GIPVRCYSAE-VVTLWYRPPDVL--FGAKLYSTSIDMW 186 Query: 365 SIGCIFAELL-TGRPLFPGKNVVHQLDIITDLLGTPSSE 478 S GCIFAEL GRPLFPG +V QL I LLGTP+ E Sbjct: 187 SAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEE 225
>CDK5_HUMAN (Q00535) Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein| kinase II catalytic subunit) (TPKII catalytic subunit) (Serine/threonine-protein kinase PSSALRE) Length = 292 Score = 123 bits (308), Expect = 4e-28 Identities = 74/159 (46%), Positives = 99/159 (62%), Gaps = 3/159 (1%) Frame = +2 Query: 11 NSKXIYVVFELMESDLHQVIRA-NDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKN 187 + K + +VFE + DL + + N DL E + FL+QLL+ L + H NV HRDLKP+N Sbjct: 72 SDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSRNVLHRDLKPQN 131 Query: 188 ILANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSK-YTPAIDIW 364 +L N + +LK+ DFGLAR P + + V T WYR P++ F +K Y+ +ID+W Sbjct: 132 LLINRNGELKLADFGLARAF--GIPVRCYSAE-VVTLWYRPPDVL--FGAKLYSTSIDMW 186 Query: 365 SIGCIFAELL-TGRPLFPGKNVVHQLDIITDLLGTPSSE 478 S GCIFAEL GRPLFPG +V QL I LLGTP+ E Sbjct: 187 SAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEE 225
>MAK_RAT (P20793) Serine/threonine-protein kinase MAK (EC 2.7.11.22) (Male| germ cell-associated kinase) Length = 622 Score = 123 bits (308), Expect = 4e-28 Identities = 66/150 (44%), Positives = 96/150 (64%), Gaps = 1/150 (0%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRANDDLTAEHY-QFFLYQLLRALKYIHGANVFHRDLKPKNILAN 199 +Y +FE M+ +L+Q+++ + L E + +YQ+L+ L +IH FHRD+KP+N+L Sbjct: 75 LYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHGFFHRDMKPENLLCM 134 Query: 200 ADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCI 379 +KI DFGLAR + P +TDYV+TRWYRAPE+ S Y+ ID+W++G I Sbjct: 135 GPELVKIADFGLARELRSQPP----YTDYVSTRWYRAPEVLLRS-SVYSSPIDVWAVGSI 189 Query: 380 FAELLTGRPLFPGKNVVHQLDIITDLLGTP 469 AEL T RPLFPG + V ++ I +LGTP Sbjct: 190 MAELYTFRPLFPGTSEVDEIFKICQVLGTP 219
>CDKL4_HUMAN (Q5MAI5) Cyclin-dependent kinase-like 4 (EC 2.7.11.22)| Length = 315 Score = 122 bits (307), Expect = 6e-28 Identities = 69/151 (45%), Positives = 97/151 (64%), Gaps = 2/151 (1%) Frame = +2 Query: 17 KXIYVVFELMESDLHQVIRANDDLTAEHY-QFFLYQLLRALKYIHGANVFHRDLKPKNIL 193 + +++VFE + L + N + A+ + L+Q L+AL + H N HRD+KP+NIL Sbjct: 74 RKMHLVFEYCDHTLLNELERNPNGVADGVIKSVLWQTLQALNFCHIHNCIHRDIKPENIL 133 Query: 194 ANADCKLKICDFGLARVSF-NDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSI 370 +KICDFG A++ DA +TDYVATRWYRAPEL ++Y ++DIW+I Sbjct: 134 ITKQGIIKICDFGFAQILIPGDA-----YTDYVATRWYRAPELLVGD-TQYGSSVDIWAI 187 Query: 371 GCIFAELLTGRPLFPGKNVVHQLDIITDLLG 463 GC+FAELLTG+PL+PGK+ V QL +I LG Sbjct: 188 GCVFAELLTGQPLWPGKSDVDQLYLIIRTLG 218
>CDC2H_PLAFK (Q07785) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (PfPK5) Length = 288 Score = 122 bits (306), Expect = 7e-28 Identities = 71/156 (45%), Positives = 96/156 (61%), Gaps = 2/156 (1%) Frame = +2 Query: 17 KXIYVVFELMESDLHQVIRANDD-LTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNIL 193 K + +VFE ++ DL +++ + L + + FL QLL + Y H V HRDLKP+N+L Sbjct: 73 KRLVLVFEHLDQDLKKLLDVCEGGLESVTAKSFLLQLLNGIAYCHDRRVLHRDLKPQNLL 132 Query: 194 ANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPE-LCGSFFSKYTPAIDIWSI 370 N + +LKI DFGLAR +T V T WYRAP+ L GS KY+ IDIWS+ Sbjct: 133 INREGELKIADFGLARAFGIPVRK---YTHEVVTLWYRAPDVLMGS--KKYSTTIDIWSV 187 Query: 371 GCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSE 478 GCIFAE++ G PLFPG + QL I +LGTP+S+ Sbjct: 188 GCIFAEMVNGTPLFPGVSEADQLMRIFRILGTPNSK 223
>CDC2H_PLAF7 (P61075) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 288 Score = 122 bits (306), Expect = 7e-28 Identities = 71/156 (45%), Positives = 96/156 (61%), Gaps = 2/156 (1%) Frame = +2 Query: 17 KXIYVVFELMESDLHQVIRANDD-LTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNIL 193 K + +VFE ++ DL +++ + L + + FL QLL + Y H V HRDLKP+N+L Sbjct: 73 KRLVLVFEHLDQDLKKLLDVCEGGLESVTAKSFLLQLLNGIAYCHDRRVLHRDLKPQNLL 132 Query: 194 ANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPE-LCGSFFSKYTPAIDIWSI 370 N + +LKI DFGLAR +T V T WYRAP+ L GS KY+ IDIWS+ Sbjct: 133 INREGELKIADFGLARAFGIPVRK---YTHEVVTLWYRAPDVLMGS--KKYSTTIDIWSV 187 Query: 371 GCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSE 478 GCIFAE++ G PLFPG + QL I +LGTP+S+ Sbjct: 188 GCIFAEMVNGTPLFPGVSEADQLMRIFRILGTPNSK 223
>GSK3_SCHPO (Q10452) Protein kinase gsk3 (EC 2.7.11.1) (Protein kinaae skp1)| Length = 387 Score = 122 bits (306), Expect = 7e-28 Identities = 68/167 (40%), Positives = 100/167 (59%), Gaps = 7/167 (4%) Frame = +2 Query: 5 GGNSKXIYV--VFELMESDLHQVIRAND----DLTAEHYQFFLYQLLRALKYIHGANVFH 166 G NS +Y+ V E M +++ R + + ++YQLLR+L YIH + + H Sbjct: 96 GDNSDEVYLNLVLEFMPETIYRASRLYTRQKLSMPMLEVKLYIYQLLRSLAYIHASGICH 155 Query: 167 RDLKPKNILANADCK-LKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKY 343 RD+KP+N+L + + LK+CDFG A++ P+ Y+ +R+YRAPEL + Y Sbjct: 156 RDIKPQNLLLDPENGILKLCDFGSAKILVAGEPNV----SYICSRYYRAPELIFGA-TDY 210 Query: 344 TPAIDIWSIGCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETL 484 T AIDIWS GC+ AEL+ G PLFPG++ + QL I +LGTPS E + Sbjct: 211 THAIDIWSTGCVMAELMLGHPLFPGESGIDQLVEIIKILGTPSREQI 257
>MSK1_MEDSA (P51137) Glycogen synthase kinase-3 homolog MsK-1 (EC 2.7.11.1)| Length = 411 Score = 122 bits (305), Expect = 1e-27 Identities = 67/158 (42%), Positives = 98/158 (62%), Gaps = 6/158 (3%) Frame = +2 Query: 29 VVFELMESDLHQVIR----ANDDLTAEHYQFFLYQLLRALKYIHGA-NVFHRDLKPKNIL 193 +V E + +H+VI+ N + + + + YQ+ RAL YIH V HRD+KP+N+L Sbjct: 148 LVLEYVPETVHRVIKHYSKLNQRMPMIYVKLYTYQIFRALSYIHRCIGVCHRDIKPQNLL 207 Query: 194 ANADC-KLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSI 370 N ++K+CDFG A+V P+ Y+ +R+YRAPEL ++YT AID+WS+ Sbjct: 208 VNPHTHQVKLCDFGSAKVLVKGEPNI----SYICSRYYRAPELIFGA-TEYTTAIDVWSV 262 Query: 371 GCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETL 484 GC+ AELL G+PLFPG+ V QL I +LGTP+ E + Sbjct: 263 GCVLAELLLGQPLFPGERGVDQLVEIIKVLGTPTREEI 300
>CDKL1_HUMAN (Q00532) Cyclin-dependent kinase-like 1 (EC 2.7.11.22)| (Serine/threonine-protein kinase KKIALRE) (Protein kinase p42 KKIALRE) Length = 357 Score = 122 bits (305), Expect = 1e-27 Identities = 63/150 (42%), Positives = 95/150 (63%), Gaps = 1/150 (0%) Frame = +2 Query: 17 KXIYVVFELMESD-LHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNIL 193 + +++VFE + LH++ R + + +Q L+A+ + H N HRD+KP+NIL Sbjct: 74 RRLHLVFEYCDHTVLHELDRYQRGVPEHLVKSITWQTLQAVNFCHKHNCIHRDVKPENIL 133 Query: 194 ANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIG 373 +K+CDFG AR+ + ++TDYVATRWYR+PEL ++Y P +D+W+IG Sbjct: 134 ITKHSVIKLCDFGFARLLTGPSD---YYTDYVATRWYRSPELLVGD-TQYGPPVDVWAIG 189 Query: 374 CIFAELLTGRPLFPGKNVVHQLDIITDLLG 463 C+FAELL+G PL+PGK+ V QL +I LG Sbjct: 190 CVFAELLSGVPLWPGKSDVDQLYLIRKTLG 219
>CDKL5_HUMAN (O76039) Cyclin-dependent kinase-like 5 (EC 2.7.11.22)| (Serine/threonine-protein kinase 9) Length = 1030 Score = 121 bits (304), Expect = 1e-27 Identities = 61/155 (39%), Positives = 104/155 (67%), Gaps = 1/155 (0%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRANDD-LTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILAN 199 +Y+VFE +E ++ +++ + + E + ++YQL++A+ + H ++ HRD+KP+N+L + Sbjct: 85 LYLVFEYVEKNMLELLEEMPNGVPPEKVKSYIYQLIKAIHWCHKNDIVHRDIKPENLLIS 144 Query: 200 ADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCI 379 + LK+CDFG AR + ++ +A + T+YVATRWYR+PEL + Y ++D+WS+GCI Sbjct: 145 HNDVLKLCDFGFAR-NLSEGNNANY-TEYVATRWYRSPELL--LGAPYGKSVDMWSVGCI 200 Query: 380 FAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETL 484 EL G+PLFPG++ + QL I +LG SE + Sbjct: 201 LGELSDGQPLFPGESEIDQLFTIQKVLGPLPSEQM 235
>CDKL1_MOUSE (Q8CEQ0) Cyclin-dependent kinase-like 1 (EC 2.7.11.22)| Length = 352 Score = 121 bits (304), Expect = 1e-27 Identities = 63/150 (42%), Positives = 94/150 (62%), Gaps = 1/150 (0%) Frame = +2 Query: 17 KXIYVVFELMESD-LHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNIL 193 + +++VFE + LH++ R + + +Q L+A+ + H N HRD+KP+NIL Sbjct: 74 RRLHLVFEYCDHTVLHELDRYQRGVPEPLVKNITWQTLQAVNFCHKHNCIHRDVKPENIL 133 Query: 194 ANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIG 373 +K+CDFG AR+ ++TDYVATRWYR+PEL ++Y P +D+W+IG Sbjct: 134 ITKQSAIKLCDFGFARLLTGPGD---YYTDYVATRWYRSPELLVGD-TQYGPPVDVWAIG 189 Query: 374 CIFAELLTGRPLFPGKNVVHQLDIITDLLG 463 C+FAELL+G PL+PGK+ V QL +I LG Sbjct: 190 CVFAELLSGVPLWPGKSDVDQLYLIRKTLG 219
>CDKL2_RABIT (Q9TTK0) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| (Serine/threonine-protein kinase KKIAMRE) Length = 566 Score = 121 bits (303), Expect = 2e-27 Identities = 66/153 (43%), Positives = 91/153 (59%), Gaps = 4/153 (2%) Frame = +2 Query: 17 KXIYVVFELME----SDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPK 184 K Y+VFE ++ DL DD + Y L+Q++ + + H N+ HRD+KP+ Sbjct: 74 KRWYLVFEFVDHTILDDLELFPNGLDDQVVQKY---LFQIINGIGFCHSHNIIHRDIKPE 130 Query: 185 NILANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIW 364 NIL + +K+CDFG AR AP ++ TDYVATRWYRAPEL KY A+D+W Sbjct: 131 NILVSQSGVVKLCDFGFARTL--AAPGEVY-TDYVATRWYRAPELLVGDV-KYGKAVDVW 186 Query: 365 SIGCIFAELLTGRPLFPGKNVVHQLDIITDLLG 463 +IGC+ E+L G PLFPG + + QL +I LG Sbjct: 187 AIGCLVTEMLMGEPLFPGDSDIDQLYLIMRCLG 219
>PHO85_DEBHA (Q6BRY2) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 330 Score = 121 bits (303), Expect = 2e-27 Identities = 71/158 (44%), Positives = 99/158 (62%), Gaps = 7/158 (4%) Frame = +2 Query: 29 VVFELMESDLHQVIRANDD---LTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILAN 199 +VFE M+ DL + + A+ + L + + F++QLL+ + + H V HRDLKP+N+L N Sbjct: 81 LVFEFMDKDLKKYMEAHGNQGALDLKIVKSFIFQLLKGIMFCHDNRVLHRDLKPQNLLIN 140 Query: 200 ADCKLKICDFGLAR---VSFNDAPSAIFWTDYVATRWYRAPE-LCGSFFSKYTPAIDIWS 367 +LK+ DFGLAR + FN +++ V T WYRAP+ L GS YT +IDIWS Sbjct: 141 NKGELKLGDFGLARAFGIPFNT------FSNEVVTLWYRAPDVLLGS--RAYTASIDIWS 192 Query: 368 IGCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSET 481 GCIFAE+ TG+PLFPG + QL I L+GTP+ T Sbjct: 193 AGCIFAEMCTGKPLFPGTSNDDQLIKIFRLMGTPNERT 230
>KSG1_ARATH (P43288) Shaggy-related protein kinase alpha (EC 2.7.11.1)| (ASK-alpha) Length = 405 Score = 120 bits (302), Expect = 2e-27 Identities = 67/158 (42%), Positives = 98/158 (62%), Gaps = 6/158 (3%) Frame = +2 Query: 29 VVFELMESDLHQVIR----ANDDLTAEHYQFFLYQLLRALKYIHGA-NVFHRDLKPKNIL 193 +V E + +H+VI+ N + + + + YQ+ RAL YIH V HRD+KP+N+L Sbjct: 142 LVLEYVPETVHRVIKHYNKLNQRMPLIYVKLYTYQIFRALSYIHRCIGVCHRDIKPQNLL 201 Query: 194 ANADC-KLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSI 370 N ++K+CDFG A+V P+ Y+ +R+YRAPEL ++YT AID+WS Sbjct: 202 VNPHTHQVKLCDFGSAKVLVKGEPNI----SYICSRYYRAPELIFGA-TEYTTAIDVWSA 256 Query: 371 GCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETL 484 GC+ AELL G+PLFPG++ V QL I +LGTP+ E + Sbjct: 257 GCVLAELLLGQPLFPGESGVDQLVEIIKVLGTPTREEI 294
>KSG5_ARATH (Q8VZD5) Shaggy-related protein kinase epsilon (EC 2.7.11.1)| (ASK-epsilon) Length = 410 Score = 120 bits (302), Expect = 2e-27 Identities = 65/140 (46%), Positives = 90/140 (64%), Gaps = 2/140 (1%) Frame = +2 Query: 71 RANDDLTAEHYQFFLYQLLRALKYIHGA-NVFHRDLKPKNILANADC-KLKICDFGLARV 244 RAN + + + + YQ+ RAL YIHG V HRD+KP+N+L N ++K+CDFG A+V Sbjct: 165 RANQRMPIIYVKLYTYQICRALAYIHGGVGVCHRDIKPQNLLVNPHTHQVKLCDFGSAKV 224 Query: 245 SFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIFAELLTGRPLFPGKN 424 P+ Y+ +R+YRAPEL ++YT IDIWS GC+ AELL G+PLFPG++ Sbjct: 225 LVKGEPNI----SYICSRYYRAPELIFGA-TEYTTTIDIWSAGCVLAELLLGQPLFPGES 279 Query: 425 VVHQLDIITDLLGTPSSETL 484 V QL I +LGTP+ E + Sbjct: 280 GVDQLVEIIKVLGTPTREEI 299
>CDK5_RAT (Q03114) Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein| kinase II catalytic subunit) (TPKII catalytic subunit) (Serine/threonine-protein kinase PSSALRE) Length = 292 Score = 120 bits (302), Expect = 2e-27 Identities = 73/159 (45%), Positives = 98/159 (61%), Gaps = 3/159 (1%) Frame = +2 Query: 11 NSKXIYVVFELMESDLHQVIRA-NDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKN 187 + K + +VFE + DL + + N DL E + L+QLL+ L + H NV HRDLKP+N Sbjct: 72 SDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSLLFQLLKGLGFCHSRNVLHRDLKPQN 131 Query: 188 ILANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSK-YTPAIDIW 364 +L N + +LK+ DFGLAR P + + V T WYR P++ F +K Y+ +ID+W Sbjct: 132 LLINRNGELKLADFGLARAF--GIPVRCYSAE-VVTLWYRPPDVL--FGAKLYSTSIDMW 186 Query: 365 SIGCIFAELL-TGRPLFPGKNVVHQLDIITDLLGTPSSE 478 S GCIFAEL GRPLFPG +V QL I LLGTP+ E Sbjct: 187 SAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEE 225
>CDK2_XENLA (P23437) Cell division protein kinase 2 (EC 2.7.11.22) (CDC2| homolog Eg1 protein kinase) Length = 297 Score = 120 bits (302), Expect = 2e-27 Identities = 69/152 (45%), Positives = 95/152 (62%), Gaps = 3/152 (1%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRAND--DLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILA 196 +Y+VFE + DL + + ++ ++ + +L+QLL+ L + H V HRDLKP+N+L Sbjct: 76 LYLVFEFLNQDLKKFMDGSNISGISLALVKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI 135 Query: 197 NADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPE-LCGSFFSKYTPAIDIWSIG 373 N+D +K+ DFGLAR P F T V T WYRAPE L G F Y+ A+DIWS+G Sbjct: 136 NSDGAIKLADFGLARAF--GVPVRTF-THEVVTLWYRAPEILLGCKF--YSTAVDIWSLG 190 Query: 374 CIFAELLTGRPLFPGKNVVHQLDIITDLLGTP 469 CIFAE++T R LFPG + + QL I LGTP Sbjct: 191 CIFAEMITRRALFPGDSEIDQLFRIFRTLGTP 222
>KSG10_ARATH (Q39019) Shaggy-related protein kinase kappa (EC 2.7.11.1)| (ASK-kappa) (AtK-1) Length = 421 Score = 120 bits (302), Expect = 2e-27 Identities = 69/158 (43%), Positives = 99/158 (62%), Gaps = 6/158 (3%) Frame = +2 Query: 29 VVFELMESDLHQVIRA----NDDLTAEHYQFFLYQLLRALKYIHGA-NVFHRDLKPKNIL 193 +V E + +++V R+ N + + + + YQ+ RAL YIH + + HRD+KP+N+L Sbjct: 156 LVLEFVPETVNRVARSYSRTNQLMPLIYVKLYTYQICRALAYIHNSFGLCHRDIKPQNLL 215 Query: 194 ANADC-KLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSI 370 N +LKICDFG A+V P+ Y+ +R+YRAPEL S+YT AIDIWS Sbjct: 216 VNPHTHQLKICDFGSAKVLVKGEPNV----SYICSRYYRAPELIFGA-SEYTTAIDIWST 270 Query: 371 GCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETL 484 GC+ AELL G+PLFPG++ V QL I +LGTP+ E + Sbjct: 271 GCVMAELLLGQPLFPGESGVDQLVEIIKVLGTPTREEI 308
>CDC2A_ARATH (P24100) Cell division control protein 2 homolog A (EC 2.7.11.22)| (EC 2.7.11.23) Length = 294 Score = 120 bits (302), Expect = 2e-27 Identities = 69/161 (42%), Positives = 99/161 (61%), Gaps = 4/161 (2%) Frame = +2 Query: 11 NSKXIYVVFELMESDLHQVIRANDDLTAEHYQF--FLYQLLRALKYIHGANVFHRDLKPK 184 + K +Y+VFE ++ DL + + + D + + + +LYQ+LR + Y H V HRDLKP+ Sbjct: 72 SEKRLYLVFEYLDLDLKKHMDSTPDFSKDLHMIKTYLYQILRGIAYCHSHRVLHRDLKPQ 131 Query: 185 NILANADCK-LKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPE-LCGSFFSKYTPAID 358 N+L + LK+ DFGLAR P F T V T WYRAPE L GS Y+ +D Sbjct: 132 NLLIDRRTNSLKLADFGLARAF--GIPVRTF-THEVVTLWYRAPEILLGSHH--YSTPVD 186 Query: 359 IWSIGCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSET 481 IWS+GCIFAE+++ +PLFPG + + QL I ++GTP +T Sbjct: 187 IWSVGCIFAEMISQKPLFPGDSEIDQLFKIFRIMGTPYEDT 227
>MAK_HUMAN (P20794) Serine/threonine-protein kinase MAK (EC 2.7.11.22) (Male| germ cell-associated kinase) Length = 623 Score = 120 bits (301), Expect = 3e-27 Identities = 65/150 (43%), Positives = 95/150 (63%), Gaps = 1/150 (0%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRANDDLTAEHY-QFFLYQLLRALKYIHGANVFHRDLKPKNILAN 199 +Y +FE M+ +L+Q+++ + L E + +YQ+L+ L +IH FHRD+KP+N+L Sbjct: 75 LYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHGFFHRDMKPENLLCM 134 Query: 200 ADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCI 379 +KI DFGLAR + P +TDYV+TRWYRAPE+ S Y+ ID+W++G I Sbjct: 135 GPELVKIADFGLARELRSQPP----YTDYVSTRWYRAPEVL-LRSSVYSSPIDVWAVGSI 189 Query: 380 FAELLTGRPLFPGKNVVHQLDIITDLLGTP 469 AEL RPLFPG + V ++ I +LGTP Sbjct: 190 MAELYMLRPLFPGTSEVDEIFKICQVLGTP 219
>CDKL2_MOUSE (Q9QUK0) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| (Serine/threonine-protein kinase KKIAMRE) Length = 568 Score = 120 bits (301), Expect = 3e-27 Identities = 64/150 (42%), Positives = 94/150 (62%), Gaps = 1/150 (0%) Frame = +2 Query: 17 KXIYVVFELMESDLHQVIRA-NDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNIL 193 K Y+VFE ++ + ++ + L + Q +L+Q++ + + H N+ HRD+KP+NIL Sbjct: 74 KRWYLVFEFVDHTILDDLKLFPNGLDYQVVQKYLFQIINGIGFCHSHNIIHRDIKPENIL 133 Query: 194 ANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIG 373 + +K+CDFG AR AP ++ TDYVATRWYRAPEL KY A+DIW+IG Sbjct: 134 VSQSGVVKLCDFGFARTL--AAPGEVY-TDYVATRWYRAPELLVGDV-KYGKAVDIWAIG 189 Query: 374 CIFAELLTGRPLFPGKNVVHQLDIITDLLG 463 C+ E+L G+PLFPG++ + QL I LG Sbjct: 190 CLVIEMLMGQPLFPGESDIDQLHHIMTCLG 219
>CDKL2_RAT (Q5XIT0) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| Length = 507 Score = 120 bits (301), Expect = 3e-27 Identities = 64/150 (42%), Positives = 94/150 (62%), Gaps = 1/150 (0%) Frame = +2 Query: 17 KXIYVVFELMESDLHQVIRA-NDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNIL 193 K Y+VFE ++ + ++ + L + Q +L+Q++ + + H N+ HRD+KP+NIL Sbjct: 74 KRWYLVFEFVDHTILDDLKLFPNGLDYQVVQKYLFQIINGIGFCHSHNIIHRDIKPENIL 133 Query: 194 ANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIG 373 + +K+CDFG AR AP ++ TDYVATRWYRAPEL KY A+DIW+IG Sbjct: 134 VSQSGVVKLCDFGFARTL--AAPGEVY-TDYVATRWYRAPELLVGDV-KYGKAVDIWAIG 189 Query: 374 CIFAELLTGRPLFPGKNVVHQLDIITDLLG 463 C+ E+L G+PLFPG++ + QL I LG Sbjct: 190 CLVIEMLMGQPLFPGESDIDQLHHIMTCLG 219
>MSK2_MEDSA (P51138) Glycogen synthase kinase-3 homolog MsK-2 (EC 2.7.11.1)| Length = 411 Score = 120 bits (300), Expect = 4e-27 Identities = 68/158 (43%), Positives = 96/158 (60%), Gaps = 6/158 (3%) Frame = +2 Query: 29 VVFELMESDLHQVIR----ANDDLTAEHYQFFLYQLLRALKYIHGA-NVFHRDLKPKNIL 193 +V E + +H+VIR N + + + + YQ+ R+L YIH V HRD+KP+N+L Sbjct: 147 LVLEFVPETVHRVIRHYSKMNQRMPLIYVKLYSYQICRSLAYIHNCVGVSHRDIKPQNLL 206 Query: 194 ANADC-KLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSI 370 N +LK+CDFG A+V P+ Y+ +R+YRAPEL ++YT AIDIWS Sbjct: 207 VNPHTHQLKLCDFGSAKVLVKGEPNI----SYICSRYYRAPELIFGA-TEYTSAIDIWSA 261 Query: 371 GCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETL 484 GC+ ELL G+PLFPG + V QL I +LGTP+ E + Sbjct: 262 GCVLGELLLGQPLFPGASGVDQLVEIIKVLGTPTREEI 299
>CDKL1_RAT (Q66HE7) Cyclin-dependent kinase-like 1 (EC 2.7.11.22)| Length = 352 Score = 120 bits (300), Expect = 4e-27 Identities = 63/150 (42%), Positives = 93/150 (62%), Gaps = 1/150 (0%) Frame = +2 Query: 17 KXIYVVFELMESD-LHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNIL 193 + +++VFE LH++ R + + +Q L+A+ + H N HRD+KP+NIL Sbjct: 74 RRLHLVFEYCHHTVLHELDRYQRGVPEPLVKNITWQTLQAVNFCHKHNCIHRDVKPENIL 133 Query: 194 ANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIG 373 +K+CDFG AR+ ++TDYVATRWYR+PEL ++Y P +D+W+IG Sbjct: 134 ITKHSVIKLCDFGFARLLTGPGD---YYTDYVATRWYRSPELLVGD-TQYGPPVDVWAIG 189 Query: 374 CIFAELLTGRPLFPGKNVVHQLDIITDLLG 463 C+FAELL+G PL+PGK+ V QL +I LG Sbjct: 190 CVFAELLSGVPLWPGKSDVDQLYLIRKTLG 219
>CDC2_VIGAC (Q41639) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) Length = 294 Score = 120 bits (300), Expect = 4e-27 Identities = 70/161 (43%), Positives = 98/161 (60%), Gaps = 4/161 (2%) Frame = +2 Query: 11 NSKXIYVVFELMESDLHQVIRANDDLTAEHYQ--FFLYQLLRALKYIHGANVFHRDLKPK 184 + K +Y+VFE ++ DL + + ++ + + Q FLYQ+L + Y H V HRDLKP+ Sbjct: 72 SEKRLYLVFEYLDLDLKKHMDSSPEFVKDPRQVKMFLYQILCGIAYCHSHRVLHRDLKPQ 131 Query: 185 NILANADCK-LKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPE-LCGSFFSKYTPAID 358 N+L + LK+ DFGLAR P F T V T WYRAPE L GS Y+ +D Sbjct: 132 NLLIDRRTNSLKLADFGLARAF--GIPVRTF-THEVVTLWYRAPEILLGS--RHYSTPVD 186 Query: 359 IWSIGCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSET 481 +WS+GCIFAE++ RPLFPG + + +L I +LGTP+ ET Sbjct: 187 VWSVGCIFAEMVNRRPLFPGDSEIDELFKIFRILGTPNEET 227
>KSG3_ARATH (P43289) Shaggy-related protein kinase gamma (EC 2.7.11.1)| (ASK-gamma) Length = 409 Score = 120 bits (300), Expect = 4e-27 Identities = 66/158 (41%), Positives = 98/158 (62%), Gaps = 6/158 (3%) Frame = +2 Query: 29 VVFELMESDLHQVIR----ANDDLTAEHYQFFLYQLLRALKYIHGA-NVFHRDLKPKNIL 193 +V E + +H+VI+ N + + + + YQ+ R+L YIH V HRD+KP+N+L Sbjct: 146 LVLEYVPETVHRVIKHYNKLNQRMPLVYVKLYTYQIFRSLSYIHRCIGVCHRDIKPQNLL 205 Query: 194 ANADC-KLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSI 370 N ++K+CDFG A+V P+ Y+ +R+YRAPEL ++YT AID+WS Sbjct: 206 VNPHTHQVKLCDFGSAKVLVKGEPNI----SYICSRYYRAPELIFGA-TEYTTAIDVWSA 260 Query: 371 GCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETL 484 GC+ AELL G+PLFPG++ V QL I +LGTP+ E + Sbjct: 261 GCVLAELLLGQPLFPGESGVDQLVEIIKVLGTPTREEI 298
>CDC2_DICDI (P34112) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) Length = 296 Score = 119 bits (299), Expect = 5e-27 Identities = 72/189 (38%), Positives = 104/189 (55%), Gaps = 11/189 (5%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANA 202 +Y+VFE ++ DL + + + L + + +LYQLL+ L Y HG + HRDLKP+N+L + Sbjct: 80 LYLVFEYLDQDLKKYMDSVPALCPQLIKSYLYQLLKGLAYSHGHRILHRDLKPQNLLIDR 139 Query: 203 DCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPE-LCGSFFSKYTPAIDIWSIGCI 379 LK+ DFGLAR P ++ T + T WYRAPE L GS Y+ +D+WS+GCI Sbjct: 140 QGALKLADFGLARAV--SIPVRVY-THEIVTLWYRAPEVLLGS--KSYSVPVDMWSVGCI 194 Query: 380 FAELLTGRPLFPGKNVVHQLDIITDLLGTPSS----------ETLSRIRNEKARRYLKLH 529 F E+L +PLF G + Q+ I +LGTP E +S N + Y K+ Sbjct: 195 FGEMLNKKPLFSGDCEIDQIFRIFRVLGTPDDSIWPGVTKLPEYVSTFPNWPGQPYNKIF 254 Query: 530 AKKTSCALD 556 + ALD Sbjct: 255 PRCEPLALD 263
>CDC2_CHERU (P93101) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) Length = 294 Score = 119 bits (299), Expect = 5e-27 Identities = 70/161 (43%), Positives = 96/161 (59%), Gaps = 4/161 (2%) Frame = +2 Query: 11 NSKXIYVVFELMESDLHQVIRANDDLTAEHYQF--FLYQLLRALKYIHGANVFHRDLKPK 184 + K +Y+VFE ++ DL + + + D + FLYQ+LR + Y H V HRDLKP+ Sbjct: 72 SEKRLYLVFEYLDLDLKKHMDSCPDFAKDPRMIKRFLYQILRGIAYCHSHRVLHRDLKPQ 131 Query: 185 NILANADCK-LKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPE-LCGSFFSKYTPAID 358 N+L + LK+ DFGLAR P F T V T WYRAPE L GS Y+ +D Sbjct: 132 NLLIDRQTNALKLADFGLARAF--GIPVRTF-THEVVTLWYRAPEILLGS--RHYSTPVD 186 Query: 359 IWSIGCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSET 481 +WS+GCIFAE++ +PLFPG + + +L I LGTP+ ET Sbjct: 187 VWSVGCIFAEMVNQKPLFPGDSEIDELFKIFRTLGTPNEET 227
>CDC2A_ANTMA (Q38772) Cell division control protein 2 homolog A (EC 2.7.11.22)| (EC 2.7.11.23) Length = 294 Score = 119 bits (299), Expect = 5e-27 Identities = 69/161 (42%), Positives = 99/161 (61%), Gaps = 4/161 (2%) Frame = +2 Query: 11 NSKXIYVVFELMESDLHQVIRANDDLTAEH--YQFFLYQLLRALKYIHGANVFHRDLKPK 184 + K +Y+VFE ++ DL + + + + + + + FLYQ+LR + Y H V HRDLKP+ Sbjct: 72 SEKRLYLVFEYLDLDLKKHMDSCPEFSQDPRLVKMFLYQILRGIAYCHSHRVLHRDLKPQ 131 Query: 185 NILANADCK-LKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPE-LCGSFFSKYTPAID 358 N+L + LK+ DFGLAR P F T V T WYRAPE L GS Y+ +D Sbjct: 132 NLLIDRRTNALKLADFGLARAF--GIPVRTF-THEVVTLWYRAPEILLGS--RHYSTPVD 186 Query: 359 IWSIGCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSET 481 +WS+GCIFAE++ RPLFPG + + +L I ++GTP+ ET Sbjct: 187 VWSVGCIFAEMVNQRPLFPGDSEIDELFKIFRVMGTPNEET 227
>CDC22_MEDSA (Q05006) Cell division control protein 2 homolog 2 (EC 2.7.11.22)| Length = 294 Score = 119 bits (299), Expect = 5e-27 Identities = 68/161 (42%), Positives = 97/161 (60%), Gaps = 4/161 (2%) Frame = +2 Query: 11 NSKXIYVVFELMESDLHQVIRANDDLTAEHYQF--FLYQLLRALKYIHGANVFHRDLKPK 184 + K +Y+VFE ++ DL + + ++ + + Q FLYQ+L + Y H V HRDLKP+ Sbjct: 72 SEKRLYLVFEYLDLDLKKFMDSSPEFAKDQRQIKMFLYQILCGIAYCHSHRVLHRDLKPQ 131 Query: 185 NILANADCK-LKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPE-LCGSFFSKYTPAID 358 N+L + +K+ DFGLAR P F T V T WYRAPE L GS Y+ +D Sbjct: 132 NLLIDRSSNAVKLADFGLARAF--GIPVRTF-THEVVTLWYRAPEILLGS--RHYSTPVD 186 Query: 359 IWSIGCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSET 481 +WS+GCIFAE++ RPLFPG + + +L I + GTP+ ET Sbjct: 187 VWSVGCIFAEMINQRPLFPGDSEIDELFKIFRITGTPNEET 227
>CDK2_MESAU (P48963) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 119 bits (299), Expect = 5e-27 Identities = 68/152 (44%), Positives = 94/152 (61%), Gaps = 3/152 (1%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRAN--DDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILA 196 +Y+VFEL+ DL + + A+ + + +L+QLL+ L + H V HRDLKP+N+L Sbjct: 76 LYLVFELLHQDLKKFMDASAVTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI 135 Query: 197 NADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPE-LCGSFFSKYTPAIDIWSIG 373 NA+ +K+ DFGLAR +T V T WYRAPE L G + Y+ A+DIWS+G Sbjct: 136 NAEGSIKLADFGLARAF---GVPVRTYTHEVVTLWYRAPEILLGCKY--YSTAVDIWSLG 190 Query: 374 CIFAELLTGRPLFPGKNVVHQLDIITDLLGTP 469 CIFAE++T R LFPG + + QL I LGTP Sbjct: 191 CIFAEMVTRRALFPGDSEIDQLFRIFRTLGTP 222
>CDK2_BOVIN (Q5E9Y0) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 119 bits (299), Expect = 5e-27 Identities = 68/152 (44%), Positives = 93/152 (61%), Gaps = 3/152 (1%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRAN--DDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILA 196 +Y+VFE + DL + + A+ + + +L+QLL+ L + H V HRDLKP+N+L Sbjct: 76 LYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI 135 Query: 197 NADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPE-LCGSFFSKYTPAIDIWSIG 373 NAD +K+ DFGLAR +T V T WYRAPE L G + Y+ A+DIWS+G Sbjct: 136 NADGSIKLADFGLARAF---GVPVRTYTHEVVTLWYRAPEILLGCKY--YSTAVDIWSLG 190 Query: 374 CIFAELLTGRPLFPGKNVVHQLDIITDLLGTP 469 CIFAE++T R LFPG + + QL I LGTP Sbjct: 191 CIFAEMVTRRALFPGDSEIDQLFRIFRTLGTP 222
>CDC22_ORYSA (P29619) Cell division control protein 2 homolog 2 (EC 2.7.11.22)| Length = 292 Score = 119 bits (298), Expect = 6e-27 Identities = 69/158 (43%), Positives = 97/158 (61%), Gaps = 3/158 (1%) Frame = +2 Query: 17 KXIYVVFELMESDLHQVIRANDDLTAEHY-QFFLYQLLRALKYIHGANVFHRDLKPKNIL 193 K IY+VFE ++ DL + + ++ D + FLYQ+LR + Y H V HRDLKP+N+L Sbjct: 74 KCIYLVFEYLDLDLKKHMDSSPDFKNHRIVKSFLYQILRGIAYCHSHRVLHRDLKPQNLL 133 Query: 194 ANADCK-LKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPE-LCGSFFSKYTPAIDIWS 367 + LK+ DFGLAR P F T V T WYRAPE L G+ Y+ +D+WS Sbjct: 134 IDRRTNSLKLADFGLARAF--GIPVRTF-THEVVTLWYRAPEILLGA--RHYSTPVDMWS 188 Query: 368 IGCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSET 481 +GCIFAE++ +PLFPG + + +L I ++GTP+ ET Sbjct: 189 VGCIFAEMVNQKPLFPGDSEIDELFKIFSIMGTPNEET 226
>MSK3_MEDSA (P51139) Glycogen synthase kinase-3 homolog MsK-3 (EC 2.7.11.1)| Length = 411 Score = 119 bits (298), Expect = 6e-27 Identities = 69/158 (43%), Positives = 97/158 (61%), Gaps = 6/158 (3%) Frame = +2 Query: 29 VVFELMESDLHQVIR----ANDDLTAEHYQFFLYQLLRALKYIHGA-NVFHRDLKPKNIL 193 +V E + + +VIR N + + + + YQ+ RAL YIH + V HRD+KP+N+L Sbjct: 147 LVLEYVPETVSRVIRHYNKMNQRMPMIYVKLYSYQICRALAYIHNSIGVCHRDIKPQNLL 206 Query: 194 ANADC-KLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSI 370 N +LKICDFG A+V P+ Y+ +R+YRAPEL ++YT AIDIWS Sbjct: 207 VNPHTHQLKICDFGSAKVLVKGEPNI----SYICSRYYRAPELIFGA-TEYTTAIDIWSA 261 Query: 371 GCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETL 484 GC+ ELL G+PLFPG++ V QL I +LGTP+ E + Sbjct: 262 GCVLGELLLGQPLFPGESGVDQLVEIIKVLGTPTREEI 299
>CRK1_LEIME (Q06309) Cell division protein kinase 2 homolog CRK1 (EC 2.7.11.23)| Length = 301 Score = 119 bits (298), Expect = 6e-27 Identities = 69/151 (45%), Positives = 96/151 (63%), Gaps = 2/151 (1%) Frame = +2 Query: 29 VVFELMESDLHQVI-RANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANAD 205 +VFE ++ DL + + R N +L A Q F+ LLR + + H +V HRDLKP+N+L + + Sbjct: 79 IVFEYLDLDLKKYLDRENGNLDAATIQHFMRDLLRGVAFCHQRSVLHRDLKPQNLLISRE 138 Query: 206 CKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPE-LCGSFFSKYTPAIDIWSIGCIF 382 +LK+ DFGL R SF A +T+ V T WYR P+ L GS +Y P +D+WS+GCIF Sbjct: 139 KELKLGDFGLGR-SF--AIPVRKFTNEVVTLWYRPPDVLLGSM--QYGPPVDVWSVGCIF 193 Query: 383 AELLTGRPLFPGKNVVHQLDIITDLLGTPSS 475 +E+ TG PLF GKN QL I LGTP++ Sbjct: 194 SEMATGTPLFAGKNDADQLMRIFRFLGTPNN 224
>CDC2_VIGUN (P52389) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) Length = 294 Score = 119 bits (298), Expect = 6e-27 Identities = 69/161 (42%), Positives = 98/161 (60%), Gaps = 4/161 (2%) Frame = +2 Query: 11 NSKXIYVVFELMESDLHQVIRANDDLTAEHYQ--FFLYQLLRALKYIHGANVFHRDLKPK 184 + K +Y+VFE ++ DL + + ++ + + Q FLYQ+L + Y H V HRDLKP+ Sbjct: 72 SEKRLYLVFEYLDLDLKKHMDSSPEFVKDPRQVKMFLYQILCGIAYCHSHRVLHRDLKPQ 131 Query: 185 NILANADCK-LKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPE-LCGSFFSKYTPAID 358 N+L + LK+ DFGLAR P F T V T WYRAPE L GS Y+ +D Sbjct: 132 NLLIDRRTNSLKLADFGLARAF--GIPVRTF-THEVVTLWYRAPEILLGS--RHYSTPVD 186 Query: 359 IWSIGCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSET 481 +WS+GC+FAE++ RPLFPG + + +L I +LGTP+ ET Sbjct: 187 VWSVGCLFAEMVNRRPLFPGDSEIDELFKIFRILGTPNEET 227
>MSK1_TOBAC (Q40518) Shaggy-related protein kinase NtK-1 (EC 2.7.11.1)| Length = 409 Score = 119 bits (298), Expect = 6e-27 Identities = 68/158 (43%), Positives = 97/158 (61%), Gaps = 6/158 (3%) Frame = +2 Query: 29 VVFELMESDLHQVIRANDDLTAEH----YQFFLYQLLRALKYIHGA-NVFHRDLKPKNIL 193 +V E + +H+VI+ + L + + YQ+ RAL YIH V HRD+KP+N+L Sbjct: 146 LVLEYVPETVHRVIKHYNKLNQRMPLILVKLYTYQIFRALSYIHHTIGVCHRDIKPQNLL 205 Query: 194 ANADC-KLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSI 370 N ++K+CDFG A+V P+ Y+ +R+YRAPEL ++YT AIDIWS Sbjct: 206 VNPHTHQVKLCDFGSAKVLVKGEPNI----SYICSRYYRAPELIFGA-TEYTTAIDIWSA 260 Query: 371 GCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETL 484 GC+ AELL G+PLFPG++ V QL I +LGTP+ E + Sbjct: 261 GCVLAELLLGQPLFPGESGVDQLVEIIKVLGTPTREEI 298
>AL2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.11.22)| (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 7 protein) Length = 384 Score = 119 bits (297), Expect = 8e-27 Identities = 67/153 (43%), Positives = 98/153 (64%), Gaps = 3/153 (1%) Frame = +2 Query: 32 VFELMESDLHQVIRANDD-LTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANADC 208 VFE M +DL Q + + L + + F++QLLR L YIH +V HRDLKP+N+L + Sbjct: 126 VFEYMHTDLAQYMSQHPGGLHPHNVRLFMFQLLRGLAYIHHQHVLHRDLKPQNLLISHLG 185 Query: 209 KLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPE-LCGSFFSKYTPAIDIWSIGCIFA 385 +LK+ DFGLAR PS + ++ V T WYR P+ L G+ ++Y+ +DIW GCIF Sbjct: 186 ELKLADFGLARA--KSIPSQTYSSE-VVTLWYRPPDALLGA--TEYSSELDIWGAGCIFI 240 Query: 386 ELLTGRPLFPG-KNVVHQLDIITDLLGTPSSET 481 E+ G+PLFPG N++ QL+ I ++LG P+ +T Sbjct: 241 EMFQGQPLFPGVSNILEQLEKIWEVLGVPTEDT 273
>GSK3B_MOUSE (Q9WV60) Glycogen synthase kinase-3 beta (EC 2.7.11.26) (GSK-3| beta) Length = 420 Score = 119 bits (297), Expect = 8e-27 Identities = 61/139 (43%), Positives = 87/139 (62%), Gaps = 1/139 (0%) Frame = +2 Query: 71 RANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANADCK-LKICDFGLARVS 247 RA L + + ++YQL R+L YIH + HRD+KP+N+L + D LK+CDFG A+ Sbjct: 148 RAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQL 207 Query: 248 FNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIFAELLTGRPLFPGKNV 427 P+ Y+ +R+YRAPEL + YT +ID+WS GC+ AELL G+P+FPG + Sbjct: 208 VRGEPNV----SYICSRYYRAPELIFGA-TDYTSSIDVWSAGCVLAELLLGQPIFPGDSG 262 Query: 428 VHQLDIITDLLGTPSSETL 484 V QL I +LGTP+ E + Sbjct: 263 VDQLVEIIKVLGTPTREQI 281
>GSK3B_HUMAN (P49841) Glycogen synthase kinase-3 beta (EC 2.7.11.26) (GSK-3| beta) Length = 420 Score = 119 bits (297), Expect = 8e-27 Identities = 61/139 (43%), Positives = 87/139 (62%), Gaps = 1/139 (0%) Frame = +2 Query: 71 RANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANADCK-LKICDFGLARVS 247 RA L + + ++YQL R+L YIH + HRD+KP+N+L + D LK+CDFG A+ Sbjct: 148 RAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQL 207 Query: 248 FNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIFAELLTGRPLFPGKNV 427 P+ Y+ +R+YRAPEL + YT +ID+WS GC+ AELL G+P+FPG + Sbjct: 208 VRGEPNV----SYICSRYYRAPELIFGA-TDYTSSIDVWSAGCVLAELLLGQPIFPGDSG 262 Query: 428 VHQLDIITDLLGTPSSETL 484 V QL I +LGTP+ E + Sbjct: 263 VDQLVEIIKVLGTPTREQI 281
>CC2H1_TRYCO (P54664) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| Length = 301 Score = 119 bits (297), Expect = 8e-27 Identities = 69/152 (45%), Positives = 93/152 (61%), Gaps = 2/152 (1%) Frame = +2 Query: 29 VVFELMESDLHQVI-RANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANAD 205 +VFE ME DL + + RA+ +L Q F+ LL+ +++ H NV HRDLKP N+L + + Sbjct: 79 LVFEYMEMDLKKYMDRASGNLDPATIQEFMRSLLKGVRFCHERNVLHRDLKPPNLLISRE 138 Query: 206 CKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPE-LCGSFFSKYTPAIDIWSIGCIF 382 +LK+ DFGL R +T V T WYR+P+ L GS ++Y +DIWS+GCIF Sbjct: 139 KELKLADFGLGRAFGIPVKK---YTHEVVTLWYRSPDVLLGS--TQYGTPVDIWSVGCIF 193 Query: 383 AELLTGRPLFPGKNVVHQLDIITDLLGTPSSE 478 AE+ G PLF GKN QL I LGTPSS+ Sbjct: 194 AEMAIGAPLFAGKNDADQLLRIFRFLGTPSSQ 225
>CDK2_RAT (Q63699) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 119 bits (297), Expect = 8e-27 Identities = 68/152 (44%), Positives = 93/152 (61%), Gaps = 3/152 (1%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRAN--DDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILA 196 +Y+VFE + DL + + A+ L + +L+QLL+ L + H V HRDLKP+N+L Sbjct: 76 LYLVFEFLHQDLKKFMDASALTGLPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI 135 Query: 197 NADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPE-LCGSFFSKYTPAIDIWSIG 373 NA+ +K+ DFGLAR +T V T WYRAPE L G + Y+ A+DIWS+G Sbjct: 136 NAEGSIKLADFGLARAF---GVPVRTYTHEVVTLWYRAPEILLGCKY--YSTAVDIWSLG 190 Query: 374 CIFAELLTGRPLFPGKNVVHQLDIITDLLGTP 469 CIFAE++T R LFPG + + QL I LGTP Sbjct: 191 CIFAEMVTRRALFPGDSEIDQLFRIFRTLGTP 222
>PHO85_CANAL (Q9HGY5) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) (CaPHO85) Length = 326 Score = 118 bits (296), Expect = 1e-26 Identities = 70/158 (44%), Positives = 97/158 (61%), Gaps = 7/158 (4%) Frame = +2 Query: 29 VVFELMESDLHQVIRANDDLTA---EHYQFFLYQLLRALKYIHGANVFHRDLKPKNILAN 199 +VFE M+ DL + + + +A + + F++QLL+ + + H V HRDLKP+N+L N Sbjct: 81 LVFEYMDKDLKKYMEVHGQQSALDLKVVKSFMFQLLKGIMFCHDNRVLHRDLKPQNLLIN 140 Query: 200 ADCKLKICDFGLAR---VSFNDAPSAIFWTDYVATRWYRAPE-LCGSFFSKYTPAIDIWS 367 +LK+ DFGLAR + FN +++ V T WYRAP+ L GS YT +IDIWS Sbjct: 141 NKGELKLGDFGLARAFGIPFNT------FSNEVVTLWYRAPDVLLGS--RAYTTSIDIWS 192 Query: 368 IGCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSET 481 GCIFAE+ TG+PLFPG QL I L+GTP+ T Sbjct: 193 AGCIFAEMCTGKPLFPGTANEDQLIKIFRLMGTPNERT 230
>KSG7_ARATH (Q39011) Shaggy-related protein kinase eta (EC 2.7.11.1) (ASK-eta)| (BRASSINOSTEROID-INSENSITIVE 2) (ULTRACURVATA1) Length = 380 Score = 118 bits (296), Expect = 1e-26 Identities = 67/158 (42%), Positives = 98/158 (62%), Gaps = 6/158 (3%) Frame = +2 Query: 29 VVFELMESDLHQVIR----ANDDLTAEHYQFFLYQLLRALKYIHG-ANVFHRDLKPKNIL 193 +V E + L++V++ AN + + + ++YQ+ R L YIH A V HRDLKP+N+L Sbjct: 113 LVMEYVPESLYRVLKHYSSANQRMPLVYVKLYMYQIFRGLAYIHNVAGVCHRDLKPQNLL 172 Query: 194 ANA-DCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSI 370 + ++KICDFG A+ + Y+ +R+YRAPEL ++YT +IDIWS Sbjct: 173 VDPLTHQVKICDFGSAKQLVKGEANI----SYICSRFYRAPELIFGA-TEYTTSIDIWSA 227 Query: 371 GCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETL 484 GC+ AELL G+PLFPG+N V QL I +LGTP+ E + Sbjct: 228 GCVLAELLLGQPLFPGENAVDQLVEIIKVLGTPTREEI 265
>CDK7_MOUSE (Q03147) Cell division protein kinase 7 (EC 2.7.11.22) (EC| 2.7.11.23) (CDK-activating kinase) (CAK) (TFIIH basal transcription factor complex kinase subunit) (39 kDa protein kinase) (P39 Mo15) (Protein-tyrosine kinase MPK-7) (CR4 protein kinas Length = 346 Score = 118 bits (296), Expect = 1e-26 Identities = 67/158 (42%), Positives = 94/158 (59%), Gaps = 1/158 (0%) Frame = +2 Query: 8 GNSKXIYVVFELMESDLHQVIRAND-DLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPK 184 G+ I +VF+ ME+DL +I+ N LT H + ++ L+ L+Y+H + HRDLKP Sbjct: 82 GHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPN 141 Query: 185 NILANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIW 364 N+L + + LK+ DFGLA+ SF A +T V TRWYRAPEL Y +D+W Sbjct: 142 NLLLDENGVLKLADFGLAK-SFGSPNRA--YTHQVVTRWYRAPELLFG-ARMYGVGVDMW 197 Query: 365 SIGCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSE 478 ++GCI AELL P PG + + QL I + LGTP+ E Sbjct: 198 AVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEE 235
>CDK7_HUMAN (P50613) Cell division protein kinase 7 (EC 2.7.11.22) (EC| 2.7.11.23) (CDK-activating kinase) (CAK) (TFIIH basal transcription factor complex kinase subunit) (39 kDa protein kinase) (P39 Mo15) (STK1) (CAK1) Length = 346 Score = 118 bits (296), Expect = 1e-26 Identities = 67/158 (42%), Positives = 94/158 (59%), Gaps = 1/158 (0%) Frame = +2 Query: 8 GNSKXIYVVFELMESDLHQVIRAND-DLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPK 184 G+ I +VF+ ME+DL +I+ N LT H + ++ L+ L+Y+H + HRDLKP Sbjct: 82 GHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPN 141 Query: 185 NILANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIW 364 N+L + + LK+ DFGLA+ SF A +T V TRWYRAPEL Y +D+W Sbjct: 142 NLLLDENGVLKLADFGLAK-SFGSPNRA--YTHQVVTRWYRAPELLFG-ARMYGVGVDMW 197 Query: 365 SIGCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSE 478 ++GCI AELL P PG + + QL I + LGTP+ E Sbjct: 198 AVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEE 235
>KSG6_ARATH (Q39010) Shaggy-related protein kinase dzeta (EC 2.7.11.1)| (ASK-dzeta) Length = 412 Score = 118 bits (295), Expect = 1e-26 Identities = 66/158 (41%), Positives = 98/158 (62%), Gaps = 6/158 (3%) Frame = +2 Query: 29 VVFELMESDLHQVIR----ANDDLTAEHYQFFLYQLLRALKYIHGA-NVFHRDLKPKNIL 193 +V E + L++V++ +N + + + + YQ+ R L YIH A V HRD+KP+N+L Sbjct: 145 LVMEYVPETLYRVLKHYTSSNQRMPIFYVKLYTYQIFRGLAYIHTAPGVCHRDIKPQNLL 204 Query: 194 ANADC-KLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSI 370 + + K+CDFG A+V P+ Y+ +R+YRAPEL ++YT +IDIWS Sbjct: 205 VDPHTHQCKLCDFGSAKVLVKGEPNI----SYICSRYYRAPELIFGA-TEYTSSIDIWSA 259 Query: 371 GCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETL 484 GC+ AELL G+PLFPG+N V QL I +LGTP+ E + Sbjct: 260 GCVLAELLLGQPLFPGENSVDQLVEIIKVLGTPTREEI 297
>GSK3B_RAT (P18266) Glycogen synthase kinase-3 beta (EC 2.7.11.26) (GSK-3| beta) (Factor A) (FA) Length = 420 Score = 118 bits (295), Expect = 1e-26 Identities = 61/139 (43%), Positives = 87/139 (62%), Gaps = 1/139 (0%) Frame = +2 Query: 71 RANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANADCK-LKICDFGLARVS 247 RA L + + ++YQL R+L YIH + HRD+KP+N+L + D LK+CDFG A+ Sbjct: 148 RAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQL 207 Query: 248 FNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIFAELLTGRPLFPGKNV 427 P+ Y+ +R+YRAPEL + YT +ID+WS GC+ AELL G+P+FPG + Sbjct: 208 VRGEPNV----SYICSRYYRAPELIFGA-TDYTSSIDMWSAGCVLAELLLGQPIFPGDSG 262 Query: 428 VHQLDIITDLLGTPSSETL 484 V QL I +LGTP+ E + Sbjct: 263 VDQLVEIIKVLGTPTREQI 281
>CDKL1_BRARE (Q6AXJ9) Cyclin-dependent kinase-like 1 (EC 2.7.11.22)| Length = 350 Score = 118 bits (295), Expect = 1e-26 Identities = 61/150 (40%), Positives = 94/150 (62%), Gaps = 1/150 (0%) Frame = +2 Query: 17 KXIYVVFELMESD-LHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNIL 193 + +++VFE + L+++ R + + ++Q L+A+ + H N HRD+KP+NIL Sbjct: 74 RKLHLVFEYCDHTVLNELDRYPRGVPEHMVKSIIWQTLQAVNFCHKQNCIHRDVKPENIL 133 Query: 194 ANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIG 373 +K+CDFG AR+ ++TD VATRWYRAPEL ++Y P +D+W++G Sbjct: 134 ITKHQVIKLCDFGFARILTGPCD---YYTDCVATRWYRAPELLVGD-TQYGPPVDVWAVG 189 Query: 374 CIFAELLTGRPLFPGKNVVHQLDIITDLLG 463 C+FAELL+G PL+PGK+ V QL +I LG Sbjct: 190 CVFAELLSGAPLWPGKSDVDQLYLIRKTLG 219
>PHO85_YEAST (P17157) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 305 Score = 118 bits (295), Expect = 1e-26 Identities = 68/155 (43%), Positives = 96/155 (61%), Gaps = 7/155 (4%) Frame = +2 Query: 29 VVFELMESDLHQVIRAND------DLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNI 190 +VFE M++DL + + + L ++F +QLL+ L + H + HRDLKP+N+ Sbjct: 80 LVFEFMDNDLKKYMDSRTVGNTPRGLELNLVKYFQWQLLQGLAFCHENKILHRDLKPQNL 139 Query: 191 LANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPE-LCGSFFSKYTPAIDIWS 367 L N +LK+ DFGLAR P F ++ V T WYRAP+ L GS Y+ +IDIWS Sbjct: 140 LINKRGQLKLGDFGLARAF--GIPVNTFSSE-VVTLWYRAPDVLMGS--RTYSTSIDIWS 194 Query: 368 IGCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPS 472 GCI AE++TG+PLFPG N QL +I D++GTP+ Sbjct: 195 CGCILAEMITGKPLFPGTNDEEQLKLIFDIMGTPN 229
>CDK2_CRIGR (O55076) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 118 bits (295), Expect = 1e-26 Identities = 67/152 (44%), Positives = 93/152 (61%), Gaps = 3/152 (1%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRAN--DDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILA 196 +Y+VFE + DL + + A+ + + +L+QLL+ L + H V HRDLKP+N+L Sbjct: 76 LYLVFEFLHQDLKKFMDASAVTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI 135 Query: 197 NADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPE-LCGSFFSKYTPAIDIWSIG 373 NA+ +K+ DFGLAR +T V T WYRAPE L G + Y+ A+DIWS+G Sbjct: 136 NAEGSIKLADFGLARAF---GVPVRTYTHEVVTLWYRAPEILLGCKY--YSTAVDIWSLG 190 Query: 374 CIFAELLTGRPLFPGKNVVHQLDIITDLLGTP 469 CIFAE++T R LFPG + + QL I LGTP Sbjct: 191 CIFAEMVTRRALFPGDSEIDQLFRIFRTLGTP 222
>CDK7_RAT (P51952) Cell division protein kinase 7 (EC 2.7.11.22) (EC| 2.7.11.23) (CDK-activating kinase) (CAK) (TFIIH basal transcription factor complex kinase subunit) (39 protein kinase) (P39 Mo15) (Fragment) Length = 329 Score = 117 bits (294), Expect = 2e-26 Identities = 67/158 (42%), Positives = 94/158 (59%), Gaps = 1/158 (0%) Frame = +2 Query: 8 GNSKXIYVVFELMESDLHQVIRAND-DLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPK 184 G+ I +VF+ ME+DL +I+ N LT H + ++ L+ L+Y+H + HRDLKP Sbjct: 74 GHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPN 133 Query: 185 NILANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIW 364 N+L + + LK+ DFGLA+ SF A +T V TRWYRAPEL Y +D+W Sbjct: 134 NLLLDENGVLKLADFGLAK-SFGSPNWA--YTHQVVTRWYRAPELLFG-ARMYGVGVDMW 189 Query: 365 SIGCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSE 478 ++GCI AELL P PG + + QL I + LGTP+ E Sbjct: 190 AVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEE 227
>KSG9_ARATH (Q39012) Shaggy-related protein kinase iota (EC 2.7.11.1)| (ASK-iota) Length = 407 Score = 117 bits (293), Expect = 2e-26 Identities = 66/158 (41%), Positives = 98/158 (62%), Gaps = 6/158 (3%) Frame = +2 Query: 29 VVFELMESDLHQVIR----ANDDLTAEHYQFFLYQLLRALKYIHGA-NVFHRDLKPKNIL 193 +V E + L++V+R +N + + + + YQ+ R L YIH V HRD+KP+N+L Sbjct: 143 LVMEYVPETLYRVLRHYTSSNQRMPIFYVKLYTYQIFRGLAYIHTVPGVCHRDVKPQNLL 202 Query: 194 ANA-DCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSI 370 + ++K+CDFG A+V P+ Y+ +R+YRAPEL ++YT +IDIWS Sbjct: 203 VDPLTHQVKLCDFGSAKVLVKGEPNI----SYICSRYYRAPELIFGA-TEYTASIDIWSA 257 Query: 371 GCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETL 484 GC+ AELL G+PLFPG+N V QL I +LGTP+ E + Sbjct: 258 GCVLAELLLGQPLFPGENSVDQLVEIIKVLGTPTREEI 295
>CDC2H_DICDI (P34117) CDC2-like serine/threonine-protein kinase CRP (EC| 2.7.11.22) (EC 2.7.11.23) Length = 292 Score = 117 bits (293), Expect = 2e-26 Identities = 66/157 (42%), Positives = 95/157 (60%), Gaps = 2/157 (1%) Frame = +2 Query: 17 KXIYVVFELMESDLHQVI-RANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNIL 193 + + +VFE ++ DL + + +++ + F+YQLL+ + + H V HRDLKP+N+L Sbjct: 74 RKLTLVFEYLDQDLKKYLDECGGEISKPTIKSFMYQLLKGVAFCHDHRVLHRDLKPQNLL 133 Query: 194 ANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPE-LCGSFFSKYTPAIDIWSI 370 N +LK+ DFGLAR + ++ V T WYRAP+ L GS KY+ IDIWS Sbjct: 134 INRKGELKLADFGLARAFGIPVRT---YSHEVVTLWYRAPDVLMGS--RKYSTPIDIWSA 188 Query: 371 GCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSET 481 CIFAE+ +GRPLFPG QL I +LGTP+ E+ Sbjct: 189 LCIFAEMASGRPLFPGSGTSDQLFRIFKILGTPNEES 225
>CDC28_CANAL (P43063) Cell division control protein 28 (EC 2.7.11.22)| Length = 317 Score = 117 bits (293), Expect = 2e-26 Identities = 66/160 (41%), Positives = 99/160 (61%), Gaps = 4/160 (2%) Frame = +2 Query: 11 NSKXIYVVFELMESDLHQVIRANDD---LTAEHYQFFLYQLLRALKYIHGANVFHRDLKP 181 +S +Y+VFE ++ DL + + + L A + F+ QL+R +K+ H V HRDLKP Sbjct: 77 DSHKLYLVFEFLDLDLKKYMESIPQGVGLGANMIKRFMNQLIRGIKHCHSHRVLHRDLKP 136 Query: 182 KNILANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPE-LCGSFFSKYTPAID 358 +N+L + + LK+ DFGLAR +F A +T V T WYRAPE L G +Y+ +D Sbjct: 137 QNLLIDKEGNLKLADFGLAR-AFGVPLRA--YTHEVVTLWYRAPEILLGG--KQYSTGVD 191 Query: 359 IWSIGCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSE 478 +WS+GCIFAE+ +PLFPG + + ++ I +LGTP+ E Sbjct: 192 MWSVGCIFAEMCNRKPLFPGDSEIDEIFRIFRILGTPNEE 231
>CC2H1_TRYBB (P38973) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| Length = 301 Score = 117 bits (293), Expect = 2e-26 Identities = 70/158 (44%), Positives = 93/158 (58%), Gaps = 2/158 (1%) Frame = +2 Query: 11 NSKXIYVVFELMESDLHQVI-RANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKN 187 + K + +VFE ME DL + + DL A Q F+ LL +++ H NV HRDLKP N Sbjct: 73 SEKRLTLVFECMEMDLKKYMDHVGGDLDAGTIQEFMRSLLSGVRFCHERNVLHRDLKPPN 132 Query: 188 ILANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPE-LCGSFFSKYTPAIDIW 364 +L + + +LK+ DFGL R P F T V T WYR+P+ L GS ++Y +DIW Sbjct: 133 LLISREKELKLADFGLGRAF--GIPVKKF-TQEVVTLWYRSPDVLLGS--TQYGTPVDIW 187 Query: 365 SIGCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSE 478 S+GCIFAE+ G PLF GKN QL I LGTP+ + Sbjct: 188 SVGCIFAEMAIGAPLFTGKNDADQLLRIFQFLGTPNRQ 225
>BUR1_GIBZE (Q4I5U9) Serine/threonine-protein kinase BUR1 (EC 2.7.11.22) (EC| 2.7.11.23) Length = 473 Score = 117 bits (293), Expect = 2e-26 Identities = 62/165 (37%), Positives = 93/165 (56%), Gaps = 9/165 (5%) Frame = +2 Query: 23 IYVVFELMESDLHQVI-RANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILAN 199 +Y+ M+ DL ++ + + ++ QLL L+Y+H + + HRD+K N+L N Sbjct: 119 VYMATPYMDHDLSGLLDNPSVQFKEPQIKCYMLQLLEGLRYLHDSRILHRDMKAANLLIN 178 Query: 200 ADCKLKICDFGLARVSFNDAPSAIF--------WTDYVATRWYRAPELCGSFFSKYTPAI 355 L+I DFGLAR P + +T V TRWYR PEL +YTPAI Sbjct: 179 NKGILQIADFGLARHYDGRTPESGVPMGEGKRDYTGLVVTRWYRPPELLLQL-RQYTPAI 237 Query: 356 DIWSIGCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSR 490 D+W +GC+F E+L G+P+ G++ QLDII DL+G+P+ E + R Sbjct: 238 DVWGVGCVFGEMLYGKPILAGESDAAQLDIIWDLMGSPNEENMPR 282
>PHO85_KLULA (Q92241) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 304 Score = 117 bits (292), Expect = 3e-26 Identities = 67/162 (41%), Positives = 98/162 (60%), Gaps = 7/162 (4%) Frame = +2 Query: 29 VVFELMESDLHQVI------RANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNI 190 +VFE M++DL + + ++ L + ++F +QLL+ + + H + HRDLKP+N+ Sbjct: 80 LVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAFCHENRILHRDLKPQNL 139 Query: 191 LANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPE-LCGSFFSKYTPAIDIWS 367 L N +LK+ DFGLAR P F ++ V T WYRAP+ L GS Y +IDIWS Sbjct: 140 LINNRGQLKLGDFGLARAF--GIPVNTFSSE-VVTLWYRAPDVLMGS--RNYCTSIDIWS 194 Query: 368 IGCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRI 493 GCI AE++ G+PLFPG N QL +I D +GTP +T ++ Sbjct: 195 CGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQV 236
>GSK3A_HUMAN (P49840) Glycogen synthase kinase-3 alpha (EC 2.7.11.26) (GSK-3| alpha) Length = 483 Score = 117 bits (292), Expect = 3e-26 Identities = 64/157 (40%), Positives = 95/157 (60%), Gaps = 5/157 (3%) Frame = +2 Query: 29 VVFELMESDLHQVIR----ANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILA 196 +V E + +++V R A + + + ++YQL R+L YIH V HRD+KP+N+L Sbjct: 193 LVLEYVPETVYRVARHFTKAKLTIPILYVKVYMYQLFRSLAYIHSQGVCHRDIKPQNLLV 252 Query: 197 NADCK-LKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIG 373 + D LK+CDFG A+ P+ Y+ +R+YRAPEL + YT +ID+WS G Sbjct: 253 DPDTAVLKLCDFGSAKQLVRGEPNV----SYICSRYYRAPELIFGA-TDYTSSIDVWSAG 307 Query: 374 CIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETL 484 C+ AELL G+P+FPG + V QL I +LGTP+ E + Sbjct: 308 CVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQI 344
>CC2H3_TRYBB (P54666) Cell division control protein 2 homolog 3 (EC 2.7.11.22)| Length = 311 Score = 117 bits (292), Expect = 3e-26 Identities = 68/151 (45%), Positives = 88/151 (58%), Gaps = 2/151 (1%) Frame = +2 Query: 23 IYVVFELMESDLHQVI-RANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILAN 199 +Y++FE ++ DL + + + T + +YQLL L + H + HRDLKP NIL Sbjct: 95 LYLIFEYVDHDLKKALEKRGGAFTGTTLKKIIYQLLEGLSFCHRHRIVHRDLKPANILVT 154 Query: 200 ADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPE-LCGSFFSKYTPAIDIWSIGC 376 D +KI DFGLAR P + T V T WYRAPE L G YTPA+D+WSIGC Sbjct: 155 TDNSVKIADFGLARAF--QIPMHTY-THEVVTLWYRAPEILLGE--KHYTPAVDMWSIGC 209 Query: 377 IFAELLTGRPLFPGKNVVHQLDIITDLLGTP 469 IFAEL G+ LF G + + QL I +LGTP Sbjct: 210 IFAELARGKVLFRGDSEIGQLFEIFQVLGTP 240
>BUR1_DEBHA (Q6BV06) Serine/threonine-protein kinase BUR1 (EC 2.7.11.22) (EC| 2.7.11.23) Length = 608 Score = 116 bits (291), Expect = 4e-26 Identities = 67/159 (42%), Positives = 88/159 (55%), Gaps = 9/159 (5%) Frame = +2 Query: 26 YVVFELMESDLHQVIR-ANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANA 202 Y V M SDL ++ N +L H + F+ QLL ++YIH HRD+K NIL + Sbjct: 125 YTVSPYMCSDLVGLLENPNINLEVSHIKCFMEQLLHGIQYIHEQMFLHRDIKAANILIDR 184 Query: 203 DCKLKICDFGLARVSFNDAPSAIF--------WTDYVATRWYRAPELCGSFFSKYTPAID 358 + LKI DFGLARV P + +T V TRWYR PEL +YT A+D Sbjct: 185 NGTLKIADFGLARVYHGSPPKFMSGPGGGERAYTGLVVTRWYRPPELLLGE-RRYTTAVD 243 Query: 359 IWSIGCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSS 475 +W IGC+F EL T +P+ GK HQ +I DL+G P+S Sbjct: 244 MWGIGCVFGELFTRKPILVGKTDSHQAQLIFDLVGPPNS 282
>BUR1_CANAL (Q9Y7W4) Serine/threonine-protein kinase BUR1 (EC 2.7.11.22) (EC| 2.7.11.23) Length = 746 Score = 116 bits (291), Expect = 4e-26 Identities = 68/163 (41%), Positives = 91/163 (55%), Gaps = 11/163 (6%) Frame = +2 Query: 26 YVVFELMESDLHQVIRANDDLTAEHYQF--FLYQLLRALKYIHGANVFHRDLKPKNILAN 199 Y V M SDL ++ N + E Q + QLL+ ++Y+H HRD+K NIL Sbjct: 130 YTVTPYMSSDLVGLLE-NPKIKLELGQIKCIMQQLLKGIQYVHNQKFLHRDIKAANILIG 188 Query: 200 ADCKLKICDFGLARVSFNDAPSAIF--------WTDYVATRWYRAPE-LCGSFFSKYTPA 352 D LKI DFGLAR+ + P +T V TRWYR PE L G KYT A Sbjct: 189 QDGVLKIADFGLARIYHGNVPRLGMGPGGGEKAYTGLVVTRWYRPPEILLGE--RKYTTA 246 Query: 353 IDIWSIGCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSET 481 +D+W IGC+FAEL TG+P+ GK+ HQ I+ +L+G+P + T Sbjct: 247 VDLWGIGCVFAELFTGKPILVGKSDSHQAQIVFELVGSPLTWT 289
>GSK3H_DICDI (P51136) Glycogen synthase kinase-3 homolog (EC 2.7.11.26) (GSK-3)| Length = 467 Score = 116 bits (291), Expect = 4e-26 Identities = 58/129 (44%), Positives = 84/129 (65%), Gaps = 2/129 (1%) Frame = +2 Query: 104 QFFLYQLLRALKYIHGANVFHRDLKPKNILANADCK-LKICDFGLARVSFNDAPSAIFWT 280 + ++YQL R++ YIH + HRD+KP+N+L + LK+CDFG A++ + Sbjct: 157 KLYIYQLCRSINYIHSLGICHRDIKPQNLLLDTSTSTLKLCDFGSAKILIKGETNV---- 212 Query: 281 DYVATRWYRAPELC-GSFFSKYTPAIDIWSIGCIFAELLTGRPLFPGKNVVHQLDIITDL 457 Y+ +R YRAPEL GS + YT ID+WS+GC+ AELL G+PLFPG+N + QL I + Sbjct: 213 SYICSRHYRAPELIFGS--TNYTTTIDVWSLGCVLAELLLGQPLFPGENGIDQLVEIIKV 270 Query: 458 LGTPSSETL 484 LGTP+ E + Sbjct: 271 LGTPTKEQI 279
>GSK3A_RAT (P18265) Glycogen synthase kinase-3 alpha (EC 2.7.11.26) (GSK-3| alpha) (Factor A) (FA) Length = 483 Score = 116 bits (291), Expect = 4e-26 Identities = 59/130 (45%), Positives = 84/130 (64%), Gaps = 1/130 (0%) Frame = +2 Query: 98 HYQFFLYQLLRALKYIHGANVFHRDLKPKNILANADCK-LKICDFGLARVSFNDAPSAIF 274 + + ++YQL R+L YIH V HRD+KP+N+L + D LK+CDFG A+ P+ Sbjct: 220 YVKVYMYQLFRSLAYIHSQGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEPNV-- 277 Query: 275 WTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIFAELLTGRPLFPGKNVVHQLDIITD 454 Y+ +R+YRAPEL + YT +ID+WS GC+ AELL G+P+FPG + V QL I Sbjct: 278 --SYICSRYYRAPELIFGA-TDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIK 334 Query: 455 LLGTPSSETL 484 +LGTP+ E + Sbjct: 335 VLGTPTREQI 344
>CDK2_CARAU (P43450) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 116 bits (291), Expect = 4e-26 Identities = 65/152 (42%), Positives = 94/152 (61%), Gaps = 3/152 (1%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRAND--DLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILA 196 +Y+VFE + DL + + ++ ++ + +L+QLL+ L + H V HRDLKP+N+L Sbjct: 76 LYLVFEFLHQDLKRFMDSSTVTGISLPLVKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI 135 Query: 197 NADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPE-LCGSFFSKYTPAIDIWSIG 373 NA ++K+ DFGLAR +T V T WYRAPE L G + Y+ A+DIWS+G Sbjct: 136 NAQGEIKLADFGLARAF---GVPVRTYTHEVVTLWYRAPEILLGCKY--YSTAVDIWSLG 190 Query: 374 CIFAELLTGRPLFPGKNVVHQLDIITDLLGTP 469 CIFAE++T + LFPG + + QL I LGTP Sbjct: 191 CIFAEMITRKALFPGDSEIDQLFRIFRTLGTP 222
>CDC2D_ANTMA (Q38775) Cell division control protein 2 homolog D (EC 2.7.11.22)| (EC 2.7.11.23) Length = 312 Score = 116 bits (290), Expect = 5e-26 Identities = 67/158 (42%), Positives = 96/158 (60%), Gaps = 6/158 (3%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRA----NDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNI 190 +Y+VFE M++DL + IR+ + + + + +YQL + + + HG V HRDLKP N+ Sbjct: 92 LYLVFEYMDTDLKKYIRSFKQTGESIAPMNVKSLMYQLCKGVAFCHGHGVLHRDLKPHNL 151 Query: 191 LANADCK-LKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPE-LCGSFFSKYTPAIDIW 364 L + LKI D GLAR +T + T WYRAPE L G+ + Y+PA+D+W Sbjct: 152 LMDRKTMMLKIADLGLARAYTLPIKK---YTHEILTLWYRAPEVLLGA--THYSPAVDMW 206 Query: 365 SIGCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSE 478 S+ CIFAEL+T + LFPG + + QL I LLGTP+ E Sbjct: 207 SVACIFAELVTQKALFPGDSELQQLLHIFRLLGTPNEE 244
>CDK2_HUMAN (P24941) Cell division protein kinase 2 (EC 2.7.11.22) (p33 protein| kinase) Length = 298 Score = 116 bits (290), Expect = 5e-26 Identities = 66/152 (43%), Positives = 93/152 (61%), Gaps = 3/152 (1%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRAN--DDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILA 196 +Y+VFE + DL + + A+ + + +L+QLL+ L + H V HRDLKP+N+L Sbjct: 76 LYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI 135 Query: 197 NADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPE-LCGSFFSKYTPAIDIWSIG 373 N + +K+ DFGLAR + +T V T WYRAPE L G + Y+ A+DIWS+G Sbjct: 136 NTEGAIKLADFGLARAFGVPVRT---YTHEVVTLWYRAPEILLGCKY--YSTAVDIWSLG 190 Query: 374 CIFAELLTGRPLFPGKNVVHQLDIITDLLGTP 469 CIFAE++T R LFPG + + QL I LGTP Sbjct: 191 CIFAEMVTRRALFPGDSEIDQLFRIFRTLGTP 222
>KC47_ORYSA (P29620) CDC2+/CDC28-related protein kinase R2 (EC 2.7.11.22)| Length = 424 Score = 116 bits (290), Expect = 5e-26 Identities = 68/152 (44%), Positives = 90/152 (59%), Gaps = 1/152 (0%) Frame = +2 Query: 23 IYVVFELMESDLHQVIR-ANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILAN 199 +++VFE ME+DL VIR N L+ + ++ +L+ L + H V HRD+KP N+L Sbjct: 91 LHLVFEFMETDLEAVIRDRNIVLSPADTKSYIQMMLKGLAFCHKKWVLHRDMKPNNLLIG 150 Query: 200 ADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCI 379 AD +LK+ DFGLAR+ +P F T V RWYRAPEL +Y A+DIW+ GCI Sbjct: 151 ADGQLKLADFGLARIF--GSPERNF-THQVFARWYRAPELLFG-TKQYGSAVDIWAAGCI 206 Query: 380 FAELLTGRPLFPGKNVVHQLDIITDLLGTPSS 475 FAELL RP G + + QL I GTP S Sbjct: 207 FAELLLRRPFLQGSSDIDQLGKIFAAFGTPKS 238
>KSG4_ARATH (Q9FVS6) Shaggy-related protein kinase delta (EC 2.7.11.1)| (ASK-delta) Length = 420 Score = 115 bits (289), Expect = 7e-26 Identities = 63/140 (45%), Positives = 88/140 (62%), Gaps = 2/140 (1%) Frame = +2 Query: 71 RANDDLTAEHYQFFLYQLLRALKYIHGA-NVFHRDLKPKNILANADC-KLKICDFGLARV 244 R N + + + + YQ+ R L Y+H + HRD+KP+N+L N +LKICDFG A+V Sbjct: 173 RMNQLMPLIYVKLYTYQICRGLAYLHNCCGLCHRDIKPQNLLVNPHTHQLKICDFGSAKV 232 Query: 245 SFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIFAELLTGRPLFPGKN 424 P+ Y+ +R+YRAPEL ++YT AIDIWS GC+ AELL G+PLFPG++ Sbjct: 233 LVKGEPNI----SYICSRYYRAPELIFGA-TEYTTAIDIWSTGCVMAELLLGQPLFPGES 287 Query: 425 VVHQLDIITDLLGTPSSETL 484 V QL I +LGTP+ E + Sbjct: 288 GVDQLVEIIKVLGTPTREEI 307
>PHO85_CANGA (Q6FKD4) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 302 Score = 115 bits (289), Expect = 7e-26 Identities = 69/158 (43%), Positives = 94/158 (59%), Gaps = 7/158 (4%) Frame = +2 Query: 29 VVFELMESDLHQVI------RANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNI 190 +VFE M++DL + + A L ++F +QLL L + H + HRDLKP+N+ Sbjct: 79 LVFEYMDNDLKKYMDSRTVGNAPRGLEMNLVKYFQWQLLEGLAFCHENKILHRDLKPQNL 138 Query: 191 LANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPE-LCGSFFSKYTPAIDIWS 367 L +LK+ DFGLAR P F ++ V T WYRAP+ L GS Y+ +IDIWS Sbjct: 139 LITKRGQLKLGDFGLARAF--GIPVNTFSSE-VVTLWYRAPDVLMGS--RTYSTSIDIWS 193 Query: 368 IGCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSET 481 GCI AE++TG+PLFPG N QL +I D +GTP+ T Sbjct: 194 CGCILAEMITGKPLFPGTNDEEQLKLIFDKMGTPNETT 231
>CDK7_XENLA (P20911) Cell division protein kinase 7 (EC 2.7.11.22) (EC| 2.7.11.23) (40 kDa protein kinase) (P40 MO15) (CDC2/CDK2,4-activating kinase) Length = 352 Score = 115 bits (289), Expect = 7e-26 Identities = 66/158 (41%), Positives = 96/158 (60%), Gaps = 1/158 (0%) Frame = +2 Query: 8 GNSKXIYVVFELMESDLHQVIRAND-DLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPK 184 G+ I +VF+ ME+DL +I+ LT H + ++ L+ L+Y+H + HRDLKP Sbjct: 88 GHKSNISLVFDFMETDLEVIIKDTSLVLTPAHIKSYMLMTLQGLEYLHHLWILHRDLKPN 147 Query: 185 NILANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIW 364 N+L + + LK+ DFGLA+ SF +P+ I+ T V TRWYR+PEL Y +D+W Sbjct: 148 NLLLDENGVLKLADFGLAK-SFG-SPNRIY-THQVVTRWYRSPELLFG-ARMYGVGVDMW 203 Query: 365 SIGCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSE 478 ++GCI AELL P PG + + QL I + LGTP+ E Sbjct: 204 AVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEE 241
>BUR1_EMENI (Q96VK3) Serine/threonine-protein kinase bur1 (EC 2.7.11.22) (EC| 2.7.11.23) (Pitalre-like kinase A) Length = 544 Score = 115 bits (289), Expect = 7e-26 Identities = 64/170 (37%), Positives = 97/170 (57%), Gaps = 10/170 (5%) Frame = +2 Query: 5 GGNSKXIYVVFELMESDLHQVIRANDDLTAE-HYQFFLYQLLRALKYIHGANVFHRDLKP 181 G +Y+VF ME DL ++ + +E + ++ QLL LKY+HG + HRD+K Sbjct: 99 GRKKPSMYMVFPYMEHDLSGLLENPEVHFSEAQIKCYMIQLLEGLKYLHGNCILHRDMKA 158 Query: 182 KNILANADCKLKICDFGLARVSFNDAP---------SAIFWTDYVATRWYRAPELCGSFF 334 N+L + L+I DFGLAR F++AP + +T V TRWYR PEL Sbjct: 159 ANLLISNQGILQIADFGLAR-PFDEAPPQPGKGAGEAKRDYTTLVVTRWYRPPELLLQL- 216 Query: 335 SKYTPAIDIWSIGCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETL 484 +YT AID+W +GC+F E+ G+P+ G + ++Q +I L+GTP+ E + Sbjct: 217 RRYTSAIDMWGVGCVFGEMFKGKPILAGNSDLNQAQLIFSLVGTPTEENM 266
>MHK_ARATH (P43294) Serine/threonine-protein kinase MHK (EC 2.7.11.22)| Length = 443 Score = 115 bits (289), Expect = 7e-26 Identities = 64/160 (40%), Positives = 99/160 (61%), Gaps = 1/160 (0%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRANDDLTAE-HYQFFLYQLLRALKYIHGANVFHRDLKPKNILAN 199 ++ +FE M+ +L+ +++ + +E + F+ Q+L+ L ++H FHRDLKP+N+L Sbjct: 83 LFFIFECMDHNLYHIMKERERPFSEGEIRSFMSQMLQGLAHMHKNGYFHRDLKPENLLVT 142 Query: 200 ADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCI 379 + LKI DFGLAR + P +T+YV+TRWYRAPE+ S YTPA+D+W++G I Sbjct: 143 NNI-LKIADFGLAREVASMPP----YTEYVSTRWYRAPEVLLQS-SLYTPAVDMWAVGAI 196 Query: 380 FAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRN 499 AEL PLFPG++ + QL I +LG P T ++ Sbjct: 197 LAELYALTPLFPGESEIDQLYKICCVLGKPDWTTFPEAKS 236
>KSG2_ARATH (O23145) Shaggy-related protein kinase beta (EC 2.7.11.1)| (ASK-beta) Length = 431 Score = 115 bits (288), Expect = 9e-26 Identities = 63/161 (39%), Positives = 96/161 (59%), Gaps = 6/161 (3%) Frame = +2 Query: 29 VVFELMESDLHQVIRA----NDDLTAEHYQFFLYQLLRALKYIHGA-NVFHRDLKPKNIL 193 +V E + +++ R+ N + + Q + YQ+ RA+ Y+H V HRD+KP+N+L Sbjct: 175 LVLEYVPETIYRASRSYTKMNQHMPLIYIQLYTYQICRAMNYLHQVVGVCHRDIKPQNLL 234 Query: 194 AN-ADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSI 370 N ++KICDFG A++ P+ Y+ +R+YRAPEL ++YT AID+WS+ Sbjct: 235 VNNVTHEVKICDFGSAKMLIPGEPNI----SYICSRYYRAPELIFGA-TEYTSAIDMWSV 289 Query: 371 GCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRI 493 GC+ AEL G PLFPG+ V QL I +LGTP+ E + + Sbjct: 290 GCVMAELFLGHPLFPGETSVDQLVEIIKILGTPAREEIKNM 330
>CDKL2_PONPY (Q5R754) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| Length = 493 Score = 115 bits (288), Expect = 9e-26 Identities = 62/150 (41%), Positives = 90/150 (60%), Gaps = 1/150 (0%) Frame = +2 Query: 17 KXIYVVFELMESDLHQVIRA-NDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNIL 193 K Y+VFE ++ + + + L + Q +L+Q++ + + H N+ HRD+KP+NIL Sbjct: 74 KRWYLVFEFVDHTILDDLELFPNGLDYQVVQKYLFQIINGIGFCHSHNIIHRDIKPENIL 133 Query: 194 ANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIG 373 + +K+CDFG AR AP ++ TDYVATRWYRAPEL KY A+D+W+IG Sbjct: 134 VSKSGVVKLCDFGFARTL--AAPGEVY-TDYVATRWYRAPELLVGDV-KYGKAVDVWAIG 189 Query: 374 CIFAELLTGRPLFPGKNVVHQLDIITDLLG 463 C+ E+ G PLFPG + + QL I LG Sbjct: 190 CLVTEMFMGEPLFPGDSDIDQLYHIMMCLG 219
>CDKL2_HUMAN (Q92772) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| (Serine/threonine-protein kinase KKIAMRE) (Protein kinase p56 KKIAMRE) Length = 493 Score = 115 bits (288), Expect = 9e-26 Identities = 62/150 (41%), Positives = 90/150 (60%), Gaps = 1/150 (0%) Frame = +2 Query: 17 KXIYVVFELMESDLHQVIRA-NDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNIL 193 K Y+VFE ++ + + + L + Q +L+Q++ + + H N+ HRD+KP+NIL Sbjct: 74 KRWYLVFEFVDHTILDDLELFPNGLDYQVVQKYLFQIINGIGFCHSHNIIHRDIKPENIL 133 Query: 194 ANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIG 373 + +K+CDFG AR AP ++ TDYVATRWYRAPEL KY A+D+W+IG Sbjct: 134 VSQSGVVKLCDFGFARTL--AAPGEVY-TDYVATRWYRAPELLVGDV-KYGKAVDVWAIG 189 Query: 374 CIFAELLTGRPLFPGKNVVHQLDIITDLLG 463 C+ E+ G PLFPG + + QL I LG Sbjct: 190 CLVTEMFMGEPLFPGDSDIDQLYHIMMCLG 219
>CDKL2_MACFA (Q4R7T5) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| Length = 570 Score = 115 bits (288), Expect = 9e-26 Identities = 62/150 (41%), Positives = 90/150 (60%), Gaps = 1/150 (0%) Frame = +2 Query: 17 KXIYVVFELMESDLHQVIRA-NDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNIL 193 K Y+VFE ++ + + + L + Q +L+Q++ + + H N+ HRD+KP+NIL Sbjct: 74 KRWYLVFEFVDHTILDDLELFPNGLDYQVVQKYLFQIINGIGFCHSHNIIHRDIKPENIL 133 Query: 194 ANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIG 373 + +K+CDFG AR AP ++ TDYVATRWYRAPEL KY A+D+W+IG Sbjct: 134 VSQSGVVKLCDFGFARTL--AAPGEVY-TDYVATRWYRAPELLVGDV-KYGKAVDVWAIG 189 Query: 374 CIFAELLTGRPLFPGKNVVHQLDIITDLLG 463 C+ E+ G PLFPG + + QL I LG Sbjct: 190 CLVTEMFMGEPLFPGDSDIDQLYHIMMCLG 219
>CD2L7_HUMAN (Q9NYV4) Cell division cycle 2-related protein kinase 7 (EC| 2.7.11.22) (CDC2-related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS) Length = 1490 Score = 115 bits (287), Expect = 1e-25 Identities = 63/149 (42%), Positives = 91/149 (61%), Gaps = 1/149 (0%) Frame = +2 Query: 26 YVVFELMESDLHQVIRAN-DDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANA 202 Y+VFE M+ DL ++ + + +H + F+ QL+ L+Y H N HRD+K NIL N Sbjct: 810 YLVFEYMDHDLMGLLESGLVHFSEDHIKSFMKQLMEGLEYCHKKNFLHRDIKCSNILLNN 869 Query: 203 DCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIF 382 ++K+ DFGLAR+ +N S + T+ V T WYR PEL +YTPAID+WS GCI Sbjct: 870 SGQIKLADFGLARL-YNSEESRPY-TNKVITLWYRPPELLLGE-ERYTPAIDVWSCGCIL 926 Query: 383 AELLTGRPLFPGKNVVHQLDIITDLLGTP 469 EL T +P+F + QL++I+ L G+P Sbjct: 927 GELFTKKPIFQANLELAQLELISRLCGSP 955
>CD2L1_HUMAN (P21127) PITSLRE serine/threonine-protein kinase CDC2L1 (EC| 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1) Length = 795 Score = 115 bits (287), Expect = 1e-25 Identities = 64/160 (40%), Positives = 93/160 (58%), Gaps = 1/160 (0%) Frame = +2 Query: 2 LGGNSKXIYVVFELMESDLHQVIRA-NDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLK 178 +G N IY+V +E DL ++ + + QLLR +K++H + HRDLK Sbjct: 505 VGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLK 564 Query: 179 PKNILANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAID 358 N+L + LK+ DFGLAR + + +T V T WYRAPEL +Y+ A+D Sbjct: 565 TSNLLLSHAGILKVGDFGLAREYGSPLKA---YTPVVVTLWYRAPELLLGA-KEYSTAVD 620 Query: 359 IWSIGCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSE 478 +WS+GCIF ELLT +PLFPGK+ + Q++ + LGTPS + Sbjct: 621 MWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEK 660
>SGG_DROME (P18431) Protein kinase shaggy (EC 2.7.11.1) (Protein zeste-white 3)| Length = 1067 Score = 115 bits (287), Expect = 1e-25 Identities = 57/142 (40%), Positives = 86/142 (60%), Gaps = 1/142 (0%) Frame = +2 Query: 62 QVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANADCK-LKICDFGLA 238 Q + + + ++YQL R+L YIH + HRD+KP+N+L + + LK+CDFG A Sbjct: 696 QYAKTKQTIPINFIRLYMYQLFRSLAYIHSLGICHRDIKPQNLLLDPETAVLKLCDFGSA 755 Query: 239 RVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIFAELLTGRPLFPG 418 + + P+ Y+ +R+YRAPEL + YT ID+WS GC+ AELL G+P+FPG Sbjct: 756 KQLLHGEPNV----SYICSRYYRAPELIFGAIN-YTTKIDVWSAGCVLAELLLGQPIFPG 810 Query: 419 KNVVHQLDIITDLLGTPSSETL 484 + V QL + +LGTP+ E + Sbjct: 811 DSGVDQLVEVIKVLGTPTREQI 832
>CDC21_MEDSA (P24923) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| (EC 2.7.11.23) (Fragment) Length = 291 Score = 114 bits (286), Expect = 2e-25 Identities = 68/161 (42%), Positives = 96/161 (59%), Gaps = 4/161 (2%) Frame = +2 Query: 11 NSKXIYVVFELMESDLHQVIRANDDLTAEHYQ--FFLYQLLRALKYIHGANVFHRDLKPK 184 + K +Y+VFE ++ DL + + ++ + + Q FLYQ+L + Y H V HRDLKP+ Sbjct: 69 SDKRLYLVFEYLDLDLKKHMDSSPEFIKDPRQVKMFLYQMLCGIAYCHSHRVLHRDLKPQ 128 Query: 185 NILANADCK-LKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPE-LCGSFFSKYTPAID 358 N+L + LK+ DFGLAR P F T V T WYRAPE L GS Y+ +D Sbjct: 129 NLLIDRRTNSLKLADFGLARAF--GIPVRTF-THEVVTLWYRAPEILLGS--RHYSTPVD 183 Query: 359 IWSIGCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSET 481 +WS+GCIFAE+ RPL PG + + +L I +LGTP+ +T Sbjct: 184 VWSVGCIFAEMANRRPLSPGDSEIDELFKIFRILGTPNEDT 224
>CDC21_ORYSA (P29618) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| Length = 294 Score = 114 bits (286), Expect = 2e-25 Identities = 67/161 (41%), Positives = 98/161 (60%), Gaps = 4/161 (2%) Frame = +2 Query: 11 NSKXIYVVFELMESDLHQVIRANDDLTAEH--YQFFLYQLLRALKYIHGANVFHRDLKPK 184 + K IY+VFE ++ DL + + + + + +LYQ+LR + Y H V HRDLKP+ Sbjct: 72 SEKRIYLVFEYLDLDLKKFMDSCPEFAKNPTLIKSYLYQILRGVAYCHSHRVLHRDLKPQ 131 Query: 185 NILANADCK-LKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPE-LCGSFFSKYTPAID 358 N+L + LK+ DFGLAR P F T V T WYRAPE L GS +Y+ +D Sbjct: 132 NLLIDRRTNALKLADFGLARAF--GIPVRTF-THEVVTLWYRAPEILLGS--RQYSTPVD 186 Query: 359 IWSIGCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSET 481 +WS+GCIFAE++ +PLFPG + + +L I +LGTP+ ++ Sbjct: 187 MWSVGCIFAEMVNQKPLFPGDSEIDELFKIFRVLGTPNEQS 227
>CD2L2_HUMAN (Q9UQ88) PITSLRE serine/threonine-protein kinase CDC2L2 (EC| 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 2) (CDK11) Length = 780 Score = 114 bits (286), Expect = 2e-25 Identities = 63/160 (39%), Positives = 93/160 (58%), Gaps = 1/160 (0%) Frame = +2 Query: 2 LGGNSKXIYVVFELMESDLHQVIRA-NDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLK 178 +G N IY+V +E DL ++ + + QLLR +K++H + HRDLK Sbjct: 490 VGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLK 549 Query: 179 PKNILANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAID 358 N+L + LK+ DFGLAR + + +T V T+WYRAPEL +Y+ A+D Sbjct: 550 TSNLLLSHAGILKVGDFGLAREYGSPLKA---YTPVVVTQWYRAPELLLGA-KEYSTAVD 605 Query: 359 IWSIGCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSE 478 +WS+GCIF ELLT +PLFPG + + Q++ + LGTPS + Sbjct: 606 MWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEK 645
>PIT1_SCHPO (O14132) Sporulation protein kinase pit1 (EC 2.7.11.1)| Length = 650 Score = 114 bits (285), Expect = 2e-25 Identities = 66/160 (41%), Positives = 101/160 (63%), Gaps = 7/160 (4%) Frame = +2 Query: 23 IYVVFELMESDLHQVI--RANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNIL- 193 +++V E ++ +L+Q+I R ND LT E Q + Q+ + L +IH FHRD+KP+NIL Sbjct: 110 LHIVMEFLDCNLYQLISTRKNDPLTLEQVQDIMRQIFKGLNHIHTNGFFHRDMKPENILI 169 Query: 194 -ANADC---KLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDI 361 +N+D +KI DFGLAR N P +T+YV+TRWYRAPEL S Y+ +DI Sbjct: 170 SSNSDSSSFNVKIADFGLAR-EINSRPP---YTEYVSTRWYRAPELL-LRDSYYSFPVDI 224 Query: 362 WSIGCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSET 481 ++ GC+ E+ T +P+FPG + QL + ++LG+P ++ Sbjct: 225 YAAGCMAFEIATLQPIFPGNDDFDQLYKMCEILGSPDEQS 264
>CDC2C_DROME (P23573) Cell division control protein 2 cognate (EC 2.7.11.22) (EC| 2.7.11.23) Length = 314 Score = 114 bits (285), Expect = 2e-25 Identities = 65/158 (41%), Positives = 100/158 (63%), Gaps = 2/158 (1%) Frame = +2 Query: 2 LGGNSKXIYVVFELMESDLHQVI-RANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLK 178 + GN+ +Y++FE + DL +++ + D T + + +++Q+L A+ + H + HRDLK Sbjct: 75 ISGNN--LYMIFEYLNMDLKKLMDKKKDVFTPQLIKSYMHQILDAVGFCHTNRILHRDLK 132 Query: 179 PKNILANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPE-LCGSFFSKYTPAI 355 P+N+L + K+K+ DFGLAR +FN A +T V T WYRAPE L G+ F Y+ + Sbjct: 133 PQNLLVDTAGKIKLADFGLAR-AFNVPMRA--YTHEVVTLWYRAPEILLGTKF--YSTGV 187 Query: 356 DIWSIGCIFAELLTGRPLFPGKNVVHQLDIITDLLGTP 469 DIWS+GCIF+E++ R LFPG + + QL I L TP Sbjct: 188 DIWSLGCIFSEMIMRRSLFPGDSEIDQLYRIFRTLSTP 225
>GSK3H_DROME (P83101) Putative glycogen synthase kinase-3 homolog (EC 2.7.11.26)| (GSK-3) (Protein gasket) Length = 501 Score = 114 bits (285), Expect = 2e-25 Identities = 63/158 (39%), Positives = 97/158 (61%), Gaps = 6/158 (3%) Frame = +2 Query: 29 VVFELMESDLHQV----IRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILA 196 +V E + L++V RA L + ++YQLLR++ Y+H HRD+KP+N+L Sbjct: 107 LVMEFLPETLYKVERQYARAKQTLPVNFVRLYMYQLLRSMGYLHSLGFCHRDIKPQNMLL 166 Query: 197 NADCK-LKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELC-GSFFSKYTPAIDIWSI 370 +++ LK+CDFG A+ + P+ Y+ +R+YRAPEL GS + YT ID+WS Sbjct: 167 DSETGVLKLCDFGSAKQLISGEPNV----SYICSRYYRAPELIFGS--TDYTTKIDMWSA 220 Query: 371 GCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETL 484 GC+ +ELL G+ +FPG + V Q+ I ++GTP+SE L Sbjct: 221 GCVMSELLLGQLIFPGDSGVDQIVEIVKVMGTPTSEQL 258
>PFTK1_MOUSE (O35495) Serine/threonine-protein kinase PFTAIRE-1 (EC 2.7.11.22)| Length = 469 Score = 114 bits (285), Expect = 2e-25 Identities = 65/158 (41%), Positives = 100/158 (63%), Gaps = 3/158 (1%) Frame = +2 Query: 17 KXIYVVFELMESDLHQVIRANDD-LTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNIL 193 + + +VFE + +DL Q + + L ++ + FL+QLLR L YIH + HRDLKP+N+L Sbjct: 204 ETLTLVFEYVHTDLCQYMEQHPGGLHPDNVKLFLFQLLRGLSYIHQRYILHRDLKPQNLL 263 Query: 194 ANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPE-LCGSFFSKYTPAIDIWSI 370 + +LK+ DFGLAR PS + ++ V T WYR P+ L GS ++Y+ +D+W + Sbjct: 264 ISDTGELKLADFGLARA--KSVPSHTY-SNEVVTLWYRPPDVLLGS--TEYSTCLDMWGV 318 Query: 371 GCIFAELLTGRPLFPG-KNVVHQLDIITDLLGTPSSET 481 GCIF E++ G FPG K++ QL+ I +LGTP+ +T Sbjct: 319 GCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDT 356
>KSG8_ARATH (Q96287) Shaggy-related protein kinase theta (EC 2.7.11.1)| (ASK-theta) Length = 472 Score = 114 bits (285), Expect = 2e-25 Identities = 62/140 (44%), Positives = 88/140 (62%), Gaps = 2/140 (1%) Frame = +2 Query: 71 RANDDLTAEHYQFFLYQLLRALKYIHGA-NVFHRDLKPKNILANADC-KLKICDFGLARV 244 + N + Q + YQ+ RAL Y+H V HRD+KP+N+L N +LKICDFG A++ Sbjct: 229 KMNQHMPIIFVQLYTYQICRALNYLHRVVGVCHRDIKPQNLLVNPQTHQLKICDFGSAKM 288 Query: 245 SFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIFAELLTGRPLFPGKN 424 P+ Y+ +R+YRAPEL ++YT AID+WS GC+ AELL G+PLFPG++ Sbjct: 289 LVPGEPNI----SYICSRYYRAPELIFGA-TEYTNAIDMWSGGCVMAELLLGQPLFPGES 343 Query: 425 VVHQLDIITDLLGTPSSETL 484 + QL I +LGTP+ E + Sbjct: 344 GIDQLVEIIKILGTPTREEI 363
>CDK6_MOUSE (Q64261) Cell division protein kinase 6 (EC 2.7.11.22)| (Serine/threonine-protein kinase PLSTIRE) (CRK2) Length = 326 Score = 114 bits (284), Expect = 3e-25 Identities = 65/157 (41%), Positives = 91/157 (57%), Gaps = 3/157 (1%) Frame = +2 Query: 29 VVFELMESDLHQVIRANDD--LTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANA 202 +VFE ++ DL + + + E + ++QLLR L ++H V HRDLKP+NIL + Sbjct: 96 LVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTS 155 Query: 203 DCKLKICDFGLARV-SFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCI 379 ++K+ DFGLAR+ SF A T V T WYRAPE+ S Y +D+WS+GCI Sbjct: 156 SGQIKLADFGLARIYSFQMA-----LTSVVVTLWYRAPEVL--LQSSYATPVDLWSVGCI 208 Query: 380 FAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSR 490 FAE+ +PLF G + V QL I D++G P E R Sbjct: 209 FAEMFRRKPLFRGSSDVDQLGKILDIIGLPGEEDWPR 245
>PEF1_SCHPO (O74456) Serine/threonine-protein kinase pef1 (EC 2.7.11.22)| (Cyclin-dependent kinase pef1) (PHO85 homolog) Length = 288 Score = 114 bits (284), Expect = 3e-25 Identities = 70/157 (44%), Positives = 94/157 (59%), Gaps = 4/157 (2%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRANDD---LTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNIL 193 + +VFE ME DL + + + L + F QLL+ + + H V HRDLKP+N+L Sbjct: 74 LMLVFEYMEKDLKKYMDTYGNQGALPPSQVKNFTQQLLKGISFCHENRVLHRDLKPQNLL 133 Query: 194 ANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPE-LCGSFFSKYTPAIDIWSI 370 N+ +LK+ DFGLAR P F ++ V T WYRAP+ L GS Y+ +IDIWS+ Sbjct: 134 INSRGELKLADFGLARSI--GIPVNTF-SNEVVTLWYRAPDVLLGS--RVYSTSIDIWSV 188 Query: 371 GCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSET 481 GCI AE+ TGRPLF G N QL I LLGTP+ ++ Sbjct: 189 GCIMAEMATGRPLFAGSNNEDQLLKIFRLLGTPTEQS 225
>KSGT_BRANA (O04160) Shaggy-related protein kinase theta (EC 2.7.11.1)| (ASK-theta) Length = 468 Score = 114 bits (284), Expect = 3e-25 Identities = 61/129 (47%), Positives = 85/129 (65%), Gaps = 2/129 (1%) Frame = +2 Query: 104 QFFLYQLLRALKYIHGA-NVFHRDLKPKNILANADC-KLKICDFGLARVSFNDAPSAIFW 277 Q + YQ+ RAL Y+H V HRD+KP+N+L N +LKICDFG A++ P+ Sbjct: 236 QLYTYQICRALNYLHRVVGVCHRDIKPQNLLVNTHTHQLKICDFGSAKMLVPGEPNI--- 292 Query: 278 TDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIFAELLTGRPLFPGKNVVHQLDIITDL 457 Y+ +R+YRAPEL ++YT AID+WS GC+ AELL G+PLFPG++ + QL I + Sbjct: 293 -SYICSRYYRAPELIFGA-TEYTNAIDMWSGGCVMAELLLGQPLFPGESGIDQLVEIIKI 350 Query: 458 LGTPSSETL 484 LGTP+ E + Sbjct: 351 LGTPTREEI 359
>CDK5_DROME (P48609) Cell division protein kinase 5 homolog (EC 2.7.11.22)| Length = 294 Score = 114 bits (284), Expect = 3e-25 Identities = 69/160 (43%), Positives = 98/160 (61%), Gaps = 3/160 (1%) Frame = +2 Query: 11 NSKXIYVVFELMESDLHQVIRA-NDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKN 187 + K + +VFE + DL + + N ++ + F+ QLLR L + H NV HRDLKP+N Sbjct: 72 SDKKLTLVFEHCDQDLKKYFDSLNGEIDMAVCRSFMLQLLRGLAFCHSHNVLHRDLKPQN 131 Query: 188 ILANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSK-YTPAIDIW 364 +L N + +LK+ DFGLAR P + + V T WYR P++ F +K YT +ID+W Sbjct: 132 LLINKNGELKLADFGLARAF--GIPVKCYSAE-VVTLWYRPPDVL--FGAKLYTTSIDMW 186 Query: 365 SIGCIFAELL-TGRPLFPGKNVVHQLDIITDLLGTPSSET 481 S GCI AEL GRPLFPG +V+ QL I +LGTP+ ++ Sbjct: 187 SAGCILAELADAGRPLFPGSDVLDQLMKIFRVLGTPNEDS 226
>MDS1_YEAST (P38615) Serine/threonine-protein kinase MDS1/RIM11 (EC 2.7.11.1)| Length = 370 Score = 114 bits (284), Expect = 3e-25 Identities = 62/158 (39%), Positives = 97/158 (61%), Gaps = 6/158 (3%) Frame = +2 Query: 29 VVFELMESDLHQVIR----ANDDLTAEHYQFFLYQLLRALKYIHG-ANVFHRDLKPKNIL 193 ++ E M L+Q +R ++ +++++QL ++L Y+H ANV HRD+KP+N+L Sbjct: 112 LILEYMPQSLYQRLRHFVHQRTPMSRLEIKYYMFQLFKSLNYLHHFANVCHRDIKPQNLL 171 Query: 194 ANADC-KLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSI 370 + + LK+CDFG A+ P+ Y+ +R+YRAPEL + YT IDIWS Sbjct: 172 VDPETWSLKLCDFGSAKQLKPTEPNV----SYICSRYYRAPELIFGA-TNYTNQIDIWSS 226 Query: 371 GCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETL 484 GC+ AELL G+P+FPG++ + QL I +LGTPS + + Sbjct: 227 GCVMAELLLGQPMFPGESGIDQLVEIIKILGTPSKQEI 264
>CDK6_HUMAN (Q00534) Cell division protein kinase 6 (EC 2.7.11.22)| (Serine/threonine-protein kinase PLSTIRE) Length = 326 Score = 113 bits (283), Expect = 3e-25 Identities = 65/157 (41%), Positives = 91/157 (57%), Gaps = 3/157 (1%) Frame = +2 Query: 29 VVFELMESDLHQVIRANDD--LTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANA 202 +VFE ++ DL + + + E + ++QLLR L ++H V HRDLKP+NIL + Sbjct: 96 LVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTS 155 Query: 203 DCKLKICDFGLARV-SFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCI 379 ++K+ DFGLAR+ SF A T V T WYRAPE+ S Y +D+WS+GCI Sbjct: 156 SGQIKLADFGLARIYSFQMA-----LTSVVVTLWYRAPEVL--LQSSYATPVDLWSVGCI 208 Query: 380 FAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSR 490 FAE+ +PLF G + V QL I D++G P E R Sbjct: 209 FAEMFRRKPLFRGSSDVDQLGKILDVIGLPGEEDWPR 245
>PFTK1_HUMAN (O94921) Serine/threonine-protein kinase PFTAIRE-1 (EC 2.7.11.22)| Length = 469 Score = 113 bits (283), Expect = 3e-25 Identities = 65/158 (41%), Positives = 100/158 (63%), Gaps = 3/158 (1%) Frame = +2 Query: 17 KXIYVVFELMESDLHQVIRANDD-LTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNIL 193 + + +VFE + +DL Q + + L ++ + FL+QLLR L YIH + HRDLKP+N+L Sbjct: 204 ETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQLLRGLSYIHQRYILHRDLKPQNLL 263 Query: 194 ANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPE-LCGSFFSKYTPAIDIWSI 370 + +LK+ DFGLAR PS + ++ V T WYR P+ L GS ++Y+ +D+W + Sbjct: 264 ISDTGELKLADFGLARA--KSVPSHTY-SNEVVTLWYRPPDVLLGS--TEYSTCLDMWGV 318 Query: 371 GCIFAELLTGRPLFPG-KNVVHQLDIITDLLGTPSSET 481 GCIF E++ G FPG K++ QL+ I +LGTP+ +T Sbjct: 319 GCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDT 356
>CDC2_SCHPO (P04551) Cell division control protein 2 (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinse) Length = 297 Score = 113 bits (283), Expect = 3e-25 Identities = 65/158 (41%), Positives = 94/158 (59%), Gaps = 6/158 (3%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRANDDLTAEHY-----QFFLYQLLRALKYIHGANVFHRDLKPKN 187 +Y+VFE ++ DL + + + A Q F YQL+ + + H + HRDLKP+N Sbjct: 80 LYLVFEFLDMDLKKYMDRISETGATSLDPRLVQKFTYQLVNGVNFCHSRRIIHRDLKPQN 139 Query: 188 ILANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPE-LCGSFFSKYTPAIDIW 364 +L + + LK+ DFGLAR SF P + T + T WYRAPE L GS Y+ +DIW Sbjct: 140 LLIDKEGNLKLADFGLAR-SFG-VPLRNY-THEIVTLWYRAPEVLLGS--RHYSTGVDIW 194 Query: 365 SIGCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSE 478 S+GCIFAE++ PLFPG + + ++ I +LGTP+ E Sbjct: 195 SVGCIFAEMIRRSPLFPGDSEIDEIFKIFQVLGTPNEE 232
>CRK1_SCHPO (Q12126) Serine/threonine-protein kinase crk1 (EC 2.7.11.23)| (Mitotic catastrophe suppressor 6) Length = 335 Score = 112 bits (281), Expect = 6e-25 Identities = 61/157 (38%), Positives = 92/157 (58%), Gaps = 1/157 (0%) Frame = +2 Query: 29 VVFELMESDLHQVIRANDDL-TAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANAD 205 ++ E ++SDL +I+ + H + ++ LLR L +IH + HRDLKP N+L ++D Sbjct: 85 IILEFLDSDLEMLIKDKFIVFQPAHIKSWMVMLLRGLHHIHSRFILHRDLKPNNLLISSD 144 Query: 206 CKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIFA 385 LK+ DFGL+R D + + V TRWYR PEL S Y +D+WS+GCIFA Sbjct: 145 GVLKLADFGLSR----DFGTPSHMSHQVITRWYRPPELFMGCRS-YGTGVDMWSVGCIFA 199 Query: 386 ELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIR 496 EL+ P PG++ + QL++I LGTP E + ++ Sbjct: 200 ELMLRTPYLPGESDLDQLNVIFRALGTPEPEVIKSMQ 236
>CDC2B_ANTMA (Q38773) Cell division control protein 2 homolog B (EC 2.7.11.22)| (EC 2.7.11.23) (Fragment) Length = 280 Score = 112 bits (281), Expect = 6e-25 Identities = 64/158 (40%), Positives = 97/158 (61%), Gaps = 4/158 (2%) Frame = +2 Query: 17 KXIYVVFELMESDLHQVIRANDDLTAEHY--QFFLYQLLRALKYIHGANVFHRDLKPKNI 190 K +Y+VFE ++ DL + + + + + + + + FL Q+LR + Y H V HRDLKP+N+ Sbjct: 61 KRLYLVFEYLDLDLKKHMDSCPEFSQDLHMVKMFLCQILRGVAYCHSHRVLHRDLKPQNL 120 Query: 191 LANADCK-LKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPE-LCGSFFSKYTPAIDIW 364 L + +K+ DFGLAR P F T V T WYRAPE L GS Y+ +D+W Sbjct: 121 LIDRGSNTIKLADFGLARAF--GIPVRTF-THEVVTLWYRAPEVLLGS--RHYSTPVDVW 175 Query: 365 SIGCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSE 478 S+GCIFAE++ +PLFPG + + +L I ++GTP+ + Sbjct: 176 SVGCIFAEMVNQKPLFPGDSEIDELHKIFRIIGTPNED 213
>GSK31_SCHPO (Q9URT9) Protein kinase gsk31 (EC 2.7.11.1)| Length = 381 Score = 112 bits (281), Expect = 6e-25 Identities = 62/151 (41%), Positives = 85/151 (56%), Gaps = 1/151 (0%) Frame = +2 Query: 38 ELMESDLHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANADCK-L 214 E + D+ R + + + +QL RAL Y+H V HRD+KP+N+L + L Sbjct: 106 ETVFDDMRWYTRRRKSIPNLSIKLYAFQLFRALAYLHSTGVCHRDIKPQNLLVDYKTGIL 165 Query: 215 KICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIFAELL 394 K+CDFG A+V P+ Y+ +R+YRAPEL + YT ID+WS C+ AEL Sbjct: 166 KLCDFGSAKVLVPSEPNV----SYICSRYYRAPELVFGA-THYTTKIDVWSAACVIAELF 220 Query: 395 TGRPLFPGKNVVHQLDIITDLLGTPSSETLS 487 GRPLFPG + V QL I +LGTPS +S Sbjct: 221 IGRPLFPGDSSVEQLVEIIRVLGTPSYHEIS 251
>CD2L1_MOUSE (P24788) PITSLRE serine/threonine-protein kinase CDC2L1 (EC| 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) Length = 784 Score = 112 bits (281), Expect = 6e-25 Identities = 64/160 (40%), Positives = 92/160 (57%), Gaps = 1/160 (0%) Frame = +2 Query: 2 LGGNSKXIYVVFELMESDLHQVIRA-NDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLK 178 +G N IY+V +E DL ++ + + QLL +K++H + HRDLK Sbjct: 494 VGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLSGVKHLHDNWILHRDLK 553 Query: 179 PKNILANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAID 358 N+L + LK+ DFGLAR + + +T V T WYRAPEL +Y+ A+D Sbjct: 554 TSNLLLSHAGILKVGDFGLAREYGSPLKA---YTPVVVTLWYRAPELLLGA-KEYSTAVD 609 Query: 359 IWSIGCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSE 478 +WS+GCIF ELLT +PLFPGK+ + Q++ I LGTPS + Sbjct: 610 MWSVGCIFGELLTQKPLFPGKSDIDQINKIFKDLGTPSEK 649
>CDC2_RANDY (Q9W739) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) Length = 302 Score = 112 bits (281), Expect = 6e-25 Identities = 64/163 (39%), Positives = 99/163 (60%), Gaps = 4/163 (2%) Frame = +2 Query: 23 IYVVFELMESDLHQV---IRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNIL 193 +Y++FE + DL + I + L A + +LYQ+L+ + + H V HRDLKP+N+L Sbjct: 76 LYLIFEFLSMDLKKYLDSIPSGQYLEAMLVKSYLYQILQGIIFCHARRVLHRDLKPQNLL 135 Query: 194 ANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPE-LCGSFFSKYTPAIDIWSI 370 ++ +K+ DFGLAR P ++ T V T WYRAPE L GS +Y+ +D+WSI Sbjct: 136 IDSKGVIKLADFGLARAF--GIPVRVY-THEVVTLWYRAPEVLLGSV--RYSTPVDVWSI 190 Query: 371 GCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRN 499 G IFAE+ + +PLF G + + QL I++L GTP++E + + Sbjct: 191 GTIFAEIASKKPLFHGDSEIDQLFRISELWGTPNNEVWPEVES 233
>CDC2_MAIZE (P23111) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) Length = 294 Score = 112 bits (281), Expect = 6e-25 Identities = 65/161 (40%), Positives = 97/161 (60%), Gaps = 4/161 (2%) Frame = +2 Query: 11 NSKXIYVVFELMESDLHQVIRANDDLTAEH--YQFFLYQLLRALKYIHGANVFHRDLKPK 184 + K IY+VFE ++ DL + + + + + +LYQ+L + Y H V HRDLKP+ Sbjct: 72 SEKRIYLVFEYLDLDLKKFMDSCPEFAKNPTLIKSYLYQILHGVAYCHSHRVLHRDLKPQ 131 Query: 185 NILANADCK-LKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPE-LCGSFFSKYTPAID 358 N+L + LK+ DFGLAR P F T V T WYRAPE L G+ +Y+ +D Sbjct: 132 NLLIDRRTNALKLADFGLARAF--GIPVRTF-THEVVTLWYRAPEILLGA--RQYSTPVD 186 Query: 359 IWSIGCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSET 481 +WS+GCIFAE++ +PLFPG + + +L I +LGTP+ ++ Sbjct: 187 VWSVGCIFAEMVNQKPLFPGDSEIDELFKIFRILGTPNEQS 227
>BUR1_ASPFU (Q4WTN5) Serine/threonine-protein kinase bur1 (EC 2.7.11.22) (EC| 2.7.11.23) Length = 580 Score = 112 bits (281), Expect = 6e-25 Identities = 61/169 (36%), Positives = 93/169 (55%), Gaps = 9/169 (5%) Frame = +2 Query: 5 GGNSKXIYVVFELMESDLHQVIRAND-DLTAEHYQFFLYQLLRALKYIHGANVFHRDLKP 181 G +Y+V ME DL ++ + T + ++ QLL LKY+HG + HRD+K Sbjct: 99 GRKKPSMYMVTPYMEHDLSGLLENPAVNFTEPQIKCYMLQLLEGLKYLHGNRILHRDMKA 158 Query: 182 KNILANADCKLKICDFGLARVSFNDAP--------SAIFWTDYVATRWYRAPELCGSFFS 337 N+L + + L+I DFGLAR P + +T V TRWYR PEL Sbjct: 159 ANLLISNNGVLQIADFGLARPYDEPPPEPGKGGGEAKRDYTTLVVTRWYRPPELLLQL-R 217 Query: 338 KYTPAIDIWSIGCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETL 484 +YT AID+W +GC+F E+ G+P+ G + ++Q +I +L+GTP+ E + Sbjct: 218 RYTTAIDMWGVGCVFGEMFKGKPILAGSSDLNQTQLIFNLVGTPTEENM 266
>PHO85_ASHGO (Q751E8) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 303 Score = 112 bits (279), Expect = 1e-24 Identities = 66/158 (41%), Positives = 95/158 (60%), Gaps = 7/158 (4%) Frame = +2 Query: 29 VVFELMESDLHQVIRANDD------LTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNI 190 +VFE M++DL + + + D L ++F +QLL+ + + H + HRDLKP+N+ Sbjct: 82 LVFEFMDNDLKKFMDSRLDREMPRGLELSLVKYFQWQLLQGVAFCHENRILHRDLKPQNL 141 Query: 191 LANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPE-LCGSFFSKYTPAIDIWS 367 L N +LK+ DFGLAR P F ++ V T WYRAP+ L GS Y +IDIWS Sbjct: 142 LINNKGQLKLGDFGLARAF--GIPVNTFSSE-VVTLWYRAPDVLMGS--RTYCTSIDIWS 196 Query: 368 IGCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSET 481 GCI AE++ G+ LFPG N QL +I + +GTP+ +T Sbjct: 197 CGCILAEMIMGKALFPGTNDDEQLKLIFETMGTPTEQT 234
>CD2L5_MOUSE (Q69ZA1) Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22)| (CDC2-related protein kinase 5) Length = 1511 Score = 112 bits (279), Expect = 1e-24 Identities = 60/149 (40%), Positives = 87/149 (58%), Gaps = 1/149 (0%) Frame = +2 Query: 26 YVVFELMESDLHQVIRAN-DDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANA 202 Y+VFE M+ DL ++ + H + F+ QL+ L Y H N HRD+K NIL N Sbjct: 788 YLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQLMEGLDYCHKKNFLHRDIKCSNILLNN 847 Query: 203 DCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIF 382 ++K+ DFGLAR+ ++ +T+ V T WYR PEL +YTPAID+WS GCI Sbjct: 848 RGQIKLADFGLARLYSSEESRP--YTNKVITLWYRPPELLLGE-ERYTPAIDVWSCGCIL 904 Query: 383 AELLTGRPLFPGKNVVHQLDIITDLLGTP 469 EL T +P+F + QL++I+ + G+P Sbjct: 905 GELFTKKPIFQANQELAQLELISRICGSP 933
>CD2L5_HUMAN (Q14004) Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22)| (CDC2-related protein kinase 5) (Cholinesterase-related cell division controller) Length = 1512 Score = 112 bits (279), Expect = 1e-24 Identities = 60/149 (40%), Positives = 87/149 (58%), Gaps = 1/149 (0%) Frame = +2 Query: 26 YVVFELMESDLHQVIRAN-DDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNILANA 202 Y+VFE M+ DL ++ + H + F+ QL+ L Y H N HRD+K NIL N Sbjct: 788 YLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQLMEGLDYCHKKNFLHRDIKCSNILLNN 847 Query: 203 DCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIF 382 ++K+ DFGLAR+ ++ +T+ V T WYR PEL +YTPAID+WS GCI Sbjct: 848 RGQIKLADFGLARLYSSEESRP--YTNKVITLWYRPPELLLGE-ERYTPAIDVWSCGCIL 904 Query: 383 AELLTGRPLFPGKNVVHQLDIITDLLGTP 469 EL T +P+F + QL++I+ + G+P Sbjct: 905 GELFTKKPIFQANQELAQLELISRICGSP 933
>CDKL3_MOUSE (Q8BLF2) Cyclin-dependent kinase-like 3 (EC 2.7.11.22)| Length = 595 Score = 111 bits (278), Expect = 1e-24 Identities = 58/137 (42%), Positives = 86/137 (62%), Gaps = 1/137 (0%) Frame = +2 Query: 17 KXIYVVFELMESD-LHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNIL 193 K I++VFE ++ L ++ L ++ + +L+Q+LRA++Y+H N+ HRD+KP+NIL Sbjct: 73 KKIHLVFEFIDHTVLDELQHYCHGLESKRLRKYLFQILRAIEYLHNNNIIHRDIKPENIL 132 Query: 194 ANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIG 373 + K+CDFG AR AP ++ TDYVATRWYRAPEL S Y +DIW++G Sbjct: 133 VSQSGITKLCDFGFARTL--AAPGDVY-TDYVATRWYRAPELVLKDTS-YGKPVDIWALG 188 Query: 374 CIFAELLTGRPLFPGKN 424 C+ E+ TG P P + Sbjct: 189 CMIIEMATGHPFLPSSS 205
>CDC28_YEAST (P00546) Cell division control protein 28 (EC 2.7.11.22)| Length = 298 Score = 111 bits (278), Expect = 1e-24 Identities = 63/154 (40%), Positives = 93/154 (60%), Gaps = 4/154 (2%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRA---NDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNIL 193 +Y+VFE ++ DL + + + L A+ + F+ QL + + Y H + HRDLKP+N+L Sbjct: 84 LYLVFEFLDLDLKRYMEGIPKDQPLGADIVKKFMMQLCKGIAYCHSHRILHRDLKPQNLL 143 Query: 194 ANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPE-LCGSFFSKYTPAIDIWSI 370 N D LK+ DFGLAR +F A +T + T WYRAPE L G +Y+ +D WSI Sbjct: 144 INKDGNLKLGDFGLAR-AFGVPLRA--YTHEIVTLWYRAPEVLLGG--KQYSTGVDTWSI 198 Query: 371 GCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPS 472 GCIFAE+ +P+F G + + Q+ I +LGTP+ Sbjct: 199 GCIFAEMCNRKPIFSGDSEIDQIFKIFRVLGTPN 232
>CDKL3_HUMAN (Q8IVW4) Cyclin-dependent kinase-like 3 (EC 2.7.11.22)| (Serine/threonine protein kinase NKIAMRE) Length = 592 Score = 111 bits (277), Expect = 2e-24 Identities = 63/153 (41%), Positives = 91/153 (59%), Gaps = 1/153 (0%) Frame = +2 Query: 17 KXIYVVFELMESD-LHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNIL 193 K I++VFE ++ L ++ L ++ + +L+Q+LRA+ Y+H N+ HRD+KP+NIL Sbjct: 73 KKIHLVFEFIDHTVLDELQHYCHGLESKRLRKYLFQILRAIDYLHSNNIIHRDIKPENIL 132 Query: 194 ANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIG 373 + K+CDFG AR AP I+ TDYVATRWYRAPEL S Y +DIW++G Sbjct: 133 VSQSGITKLCDFGFARTL--AAPGDIY-TDYVATRWYRAPELVLKDTS-YGKPVDIWALG 188 Query: 374 CIFAELLTGRPLFPGKNVVHQLDIITDLLGTPS 472 C+ E+ TG P P + + L I +G S Sbjct: 189 CMIIEMATGNPYLPSSSDLDLLHKIVLKVGNLS 221
>CDKL3_MACFA (Q4R8T9) Cyclin-dependent kinase-like 3 (EC 2.7.11.22)| Length = 590 Score = 111 bits (277), Expect = 2e-24 Identities = 63/153 (41%), Positives = 91/153 (59%), Gaps = 1/153 (0%) Frame = +2 Query: 17 KXIYVVFELMESD-LHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNIL 193 K I++VFE ++ L ++ L ++ + +L+Q+LRA+ Y+H N+ HRD+KP+NIL Sbjct: 73 KKIHLVFEFIDHTVLDELQHYCHGLESKRLRKYLFQILRAIDYLHSNNIIHRDIKPENIL 132 Query: 194 ANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIG 373 + K+CDFG AR AP I+ TDYVATRWYRAPEL S Y +DIW++G Sbjct: 133 VSQSGITKLCDFGFARTL--AAPGDIY-TDYVATRWYRAPELVLKDTS-YGKPVDIWALG 188 Query: 374 CIFAELLTGRPLFPGKNVVHQLDIITDLLGTPS 472 C+ E+ TG P P + + L I +G S Sbjct: 189 CMIIEMATGNPYLPSSSDLDLLHKIVLKVGNLS 221
>CDC21_XENLA (P35567) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| (EC 2.7.11.23) (p34 protein kinase 1) Length = 302 Score = 111 bits (277), Expect = 2e-24 Identities = 64/166 (38%), Positives = 98/166 (59%), Gaps = 7/166 (4%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRANDDLTAEHY------QFFLYQLLRALKYIHGANVFHRDLKPK 184 +Y++FE + DL + + D + + Y + +LYQ+L+ + + H V HRDLKP+ Sbjct: 76 LYLIFEFLSMDLKKYL---DSIPSGQYIDTMLVKSYLYQILQGIVFCHSRRVLHRDLKPQ 132 Query: 185 NILANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPE-LCGSFFSKYTPAIDI 361 N+L ++ +K+ DFGLAR P ++ T V T WYRAPE L GS +Y+ +D+ Sbjct: 133 NLLIDSKGVIKLADFGLARAF--GIPVRVY-THEVVTLWYRAPEVLLGSV--RYSTPVDV 187 Query: 362 WSIGCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRN 499 WSIG IFAE+ T +PLF G + + QL I LGTP++E + + Sbjct: 188 WSIGTIFAEIATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVES 233
>BUR1_YEAST (P23293) Serine/threonine-protein kinase BUR1 (EC 2.7.11.22) (EC| 2.7.11.23) (Suppressor of GPA1-Vall50 mutation protein 1) (Bypass UAS requirement protein 1) Length = 657 Score = 111 bits (277), Expect = 2e-24 Identities = 64/165 (38%), Positives = 89/165 (53%), Gaps = 11/165 (6%) Frame = +2 Query: 17 KXIYVVFELMESDLHQVIRANDDLTAEHYQF--FLYQLLRALKYIHGANVFHRDLKPKNI 190 K Y++ M +DL V+ N + E + Q+L L YIH A HRD+K NI Sbjct: 143 KSFYMILPYMVADLSGVLH-NPRINLEMCDIKNMMLQILEGLNYIHCAKFMHRDIKTANI 201 Query: 191 LANADCKLKICDFGLARVSFNDAPSAIF---------WTDYVATRWYRAPELCGSFFSKY 343 L + + LK+ DFGLAR+ + P+ + +T V TRWYRAPEL +Y Sbjct: 202 LIDHNGVLKLADFGLARLYYGCPPNLKYPGGAGSGAKYTSVVVTRWYRAPELVLGD-KQY 260 Query: 344 TPAIDIWSIGCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSE 478 T A+DIW +GC+FAE +P+ GK + Q +I LLGTP+ E Sbjct: 261 TTAVDIWGVGCVFAEFFEKKPILQGKTDIDQGHVIFKLLGTPTEE 305
>CDKL3_RAT (Q9JM01) Cyclin-dependent kinase-like 3 (EC 2.7.11.22)| (Serine/threonine protein kinase NKIATRE) Length = 593 Score = 110 bits (275), Expect = 3e-24 Identities = 57/137 (41%), Positives = 86/137 (62%), Gaps = 1/137 (0%) Frame = +2 Query: 17 KXIYVVFELMESD-LHQVIRANDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNIL 193 K I++VFE ++ L ++ L ++ + +L+Q+LRA++Y+H N+ HRD+KP+NIL Sbjct: 73 KKIHLVFEFIDHTVLDELQHYCHGLESKRLRKYLFQILRAIEYLHNNNIIHRDIKPENIL 132 Query: 194 ANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIG 373 + K+CDFG AR AP ++ TDYVATRWYRAPEL + Y +DIW++G Sbjct: 133 VSQSGITKLCDFGFARTL--AAPGDVY-TDYVATRWYRAPELVLK-DTTYGKPVDIWALG 188 Query: 374 CIFAELLTGRPLFPGKN 424 C+ E+ TG P P + Sbjct: 189 CMIIEMATGNPYLPSSS 205
>CDC2_RAT (P39951) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 110 bits (275), Expect = 3e-24 Identities = 63/163 (38%), Positives = 97/163 (59%), Gaps = 4/163 (2%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRA---NDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNIL 193 +Y++FE + DL + + + + + + +LYQ+L+ + + H V HRDLKP+N+L Sbjct: 76 LYLIFEFLSMDLKKYLDSIPPGQFMDSSLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLL 135 Query: 194 ANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPE-LCGSFFSKYTPAIDIWSI 370 + +K+ DFGLAR P ++ T V T WYR+PE L GS ++Y+ +DIWSI Sbjct: 136 IDDKGTIKLADFGLARAF--GIPIRVY-THEVVTLWYRSPEVLLGS--ARYSTPVDIWSI 190 Query: 371 GCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRN 499 G IFAEL T +PLF G + + QL I LGTP++E + + Sbjct: 191 GTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVES 233
>CDC2_PONPY (Q5RCH1) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 110 bits (275), Expect = 3e-24 Identities = 63/163 (38%), Positives = 97/163 (59%), Gaps = 4/163 (2%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRA---NDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNIL 193 +Y++FE + DL + + + + + + +LYQ+L+ + + H V HRDLKP+N+L Sbjct: 76 LYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLL 135 Query: 194 ANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPE-LCGSFFSKYTPAIDIWSI 370 + +K+ DFGLAR P ++ T V T WYR+PE L GS ++Y+ +DIWSI Sbjct: 136 IDDKGTIKLADFGLARAF--GIPIRVY-THEVVTLWYRSPEVLLGS--ARYSTPVDIWSI 190 Query: 371 GCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRN 499 G IFAEL T +PLF G + + QL I LGTP++E + + Sbjct: 191 GTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVES 233
>CDC2_HUMAN (P06493) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 110 bits (275), Expect = 3e-24 Identities = 63/163 (38%), Positives = 97/163 (59%), Gaps = 4/163 (2%) Frame = +2 Query: 23 IYVVFELMESDLHQVIRA---NDDLTAEHYQFFLYQLLRALKYIHGANVFHRDLKPKNIL 193 +Y++FE + DL + + + + + + +LYQ+L+ + + H V HRDLKP+N+L Sbjct: 76 LYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLL 135 Query: 194 ANADCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPE-LCGSFFSKYTPAIDIWSI 370 + +K+ DFGLAR P ++ T V T WYR+PE L GS ++Y+ +DIWSI Sbjct: 136 IDDKGTIKLADFGLARAF--GIPIRVY-THEVVTLWYRSPEVLLGS--ARYSTPVDIWSI 190 Query: 371 GCIFAELLTGRPLFPGKNVVHQLDIITDLLGTPSSETLSRIRN 499 G IFAEL T +PLF G + + QL I LGTP++E + + Sbjct: 191 GTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVES 233 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 84,132,293 Number of Sequences: 219361 Number of extensions: 1850688 Number of successful extensions: 8518 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 6427 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 6731 length of database: 80,573,946 effective HSP length: 106 effective length of database: 57,321,680 effective search space used: 4986986160 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
