ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | basd12c15 |
|---|---|
| Clone Library Name | barley_pub |
>CPK15_ARATH (P92937) CBL-interacting serine/threonine-protein kinase 15 (EC| 2.7.11.1) (Serine/threonine-protein kinase ATPK10) (SOS2-like protein kinase PKS3) (SOS-interacting protein 2) (SNF1-related kinase 3.1) Length = 421 Score = 157 bits (398), Expect = 2e-38 Identities = 76/124 (61%), Positives = 102/124 (82%) Frame = +1 Query: 259 MENSGKIVMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRRE 438 ME G ++M RYE+G+ LG+G F KV++A++L++ VAIK++DKE +LKVG+ EQ++RE Sbjct: 1 MEKKGSVLMLRYEVGKFLGQGTFAKVYHARHLKTGDSVAIKVIDKERILKVGMTEQIKRE 60 Query: 439 ITTMRLVAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLI 618 I+ MRL+ H +IV+LHEVMAT+SKIYFVME++KGGELF+KVS GKL E A KYFQQL+ Sbjct: 61 ISAMRLLRHPNIVELHEVMATKSKIYFVMEHVKGGELFNKVS-TGKLREDVARKYFQQLV 119 Query: 619 SAVD 630 AVD Sbjct: 120 RAVD 123
>CIPK1_ORYSA (Q6X4A2) CIPK-like protein 1 (EC 2.7.11.1) (OsCK1)| Length = 449 Score = 134 bits (337), Expect = 2e-31 Identities = 64/116 (55%), Positives = 90/116 (77%) Frame = +1 Query: 283 MGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVA 462 +G+YELGR +G+G F KV +AKN E++ VAIK++DKE V K L EQ+RREI TM+LV Sbjct: 17 VGKYELGRTIGEGTFAKVRFAKNTENDEPVAIKILDKEKVQKHRLVEQIRREICTMKLVK 76 Query: 463 HKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAVD 630 H ++V+L EVM ++++I+ V+EY+ GGELF+ ++ G+L E A KYFQQLI+AVD Sbjct: 77 HPNVVRLFEVMGSKARIFIVLEYVTGGELFEIIATNGRLKEEEARKYFQQLINAVD 132
>CPK11_ARATH (O22932) CBL-interacting serine/threonine-protein kinase 11 (EC| 2.7.11.1) (SOS2-like protein kinase PKS5) (SOS-interacting protein 4) (SNF1-related kinase 3.22) Length = 435 Score = 132 bits (333), Expect = 6e-31 Identities = 64/125 (51%), Positives = 97/125 (77%), Gaps = 1/125 (0%) Frame = +1 Query: 256 GMENSGKIVMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVL-KVGLAEQVR 432 G ++ + G+YELG+LLG GAF KV +A++ + + VA+K+++K+ +L LA ++ Sbjct: 9 GSGDNNDALFGKYELGKLLGCGAFAKVFHARDRRTGQSVAVKILNKKKLLTNPALANNIK 68 Query: 433 REITTMRLVAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQ 612 REI+ MR ++H +IV+LHEVMAT+SKI+F ME++KGGELF+K+SK G+L+E + +YFQQ Sbjct: 69 REISIMRRLSHPNIVKLHEVMATKSKIFFAMEFVKGGELFNKISKHGRLSEDLSRRYFQQ 128 Query: 613 LISAV 627 LISAV Sbjct: 129 LISAV 133
>CPK24_ARATH (Q9LDI3) CBL-interacting serine/threonine-protein kinase 24 (EC| 2.7.11.1) (SNF1-related kinase 3.11) (SALT OVERLY SENSITIVE 2 protein) Length = 446 Score = 127 bits (318), Expect = 4e-29 Identities = 57/115 (49%), Positives = 88/115 (76%) Frame = +1 Query: 283 MGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVA 462 +G+YE+GR +G+G F KV +A+N ++ VAIK+M K T+LK + +Q++REI+ M++V Sbjct: 8 VGKYEVGRTIGEGTFAKVKFARNTDTGDNVAIKIMAKSTILKNRMVDQIKREISIMKIVR 67 Query: 463 HKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 H +IV+L+EV+A+ SKIY V+E++ GGELFD++ G+L E + KYFQQL+ AV Sbjct: 68 HPNIVRLYEVLASPSKIYIVLEFVTGGELFDRIVHKGRLEESESRKYFQQLVDAV 122
>CIPK1_ARATH (Q8RWC9) CBL-interacting serine/threonine-protein kinase 1 (EC| 2.7.11.1) (SOS2-like protein kinase PKS13) (SNF1-related kinase 3.16) Length = 444 Score = 117 bits (294), Expect = 2e-26 Identities = 55/115 (47%), Positives = 81/115 (70%) Frame = +1 Query: 283 MGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVA 462 +G+YELGR LG+G FGKV +AK+ S A+K++DK + + + Q++REI T++++ Sbjct: 17 LGKYELGRTLGEGNFGKVKFAKDTVSGHSFAVKIIDKSRIADLNFSLQIKREIRTLKMLK 76 Query: 463 HKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 H IV+LHEV+A+++KI VME + GGELFD++ GKLTE K FQQLI + Sbjct: 77 HPHIVRLHEVLASKTKINMVMELVTGGELFDRIVSNGKLTETDGRKMFQQLIDGI 131
>AAPK1_HUMAN (Q13131) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMPK alpha-1 chain) Length = 550 Score = 107 bits (267), Expect = 3e-23 Identities = 50/128 (39%), Positives = 84/128 (65%) Frame = +1 Query: 247 TLEGMENSGKIVMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQ 426 T E ++ G++ +G Y LG LG G FGKV K+ + VA+K+++++ + + + + Sbjct: 3 TAEKQKHDGRVKIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGK 62 Query: 427 VRREITTMRLVAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYF 606 +RREI ++L H I++L++V++T S I+ VMEY+ GGELFD + K G+L E + + F Sbjct: 63 IRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLF 122 Query: 607 QQLISAVD 630 QQ++S VD Sbjct: 123 QQILSGVD 130
>AAPK1_PONPY (Q5RDH5) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMPK alpha-1 chain) Length = 550 Score = 107 bits (266), Expect = 4e-23 Identities = 50/128 (39%), Positives = 84/128 (65%) Frame = +1 Query: 247 TLEGMENSGKIVMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQ 426 T E ++ G++ +G Y LG LG G FGKV K+ + VA+K+++++ + + + + Sbjct: 3 TAEKQKHDGRVRIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGK 62 Query: 427 VRREITTMRLVAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYF 606 +RREI ++L H I++L++V++T S I+ VMEY+ GGELFD + K G+L E + + F Sbjct: 63 IRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLF 122 Query: 607 QQLISAVD 630 QQ++S VD Sbjct: 123 QQILSGVD 130
>KIN11_ARATH (P92958) SNF1-related protein kinase catalytic alpha subunit KIN11| (EC 2.7.11.1) (AKIN11) (AKIN alpha1) Length = 512 Score = 107 bits (266), Expect = 4e-23 Identities = 52/122 (42%), Positives = 82/122 (67%) Frame = +1 Query: 265 NSGKIVMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREIT 444 N + ++ Y+LG+ LG G+FGKV A+++ + VAIK++++ + + + E+VRREI Sbjct: 11 NGVESILPNYKLGKTLGIGSFGKVKIAEHVVTGHKVAIKILNRRKIKNMEMEEKVRREIK 70 Query: 445 TMRLVAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISA 624 +RL H I++ +EV+ T S IY VMEY+K GELFD + + G+L E A +FQQ+IS Sbjct: 71 ILRLFMHPHIIRQYEVIETTSDIYVVMEYVKSGELFDYIVEKGRLQEDEARNFFQQIISG 130 Query: 625 VD 630 V+ Sbjct: 131 VE 132
>AAPK1_RAT (P54645) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMPK alpha-1 chain) Length = 548 Score = 105 bits (263), Expect = 8e-23 Identities = 49/126 (38%), Positives = 83/126 (65%) Frame = +1 Query: 253 EGMENSGKIVMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVR 432 E ++ G++ +G Y LG LG G FGKV K+ + VA+K+++++ + + + ++R Sbjct: 3 EKQKHDGRVKIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIR 62 Query: 433 REITTMRLVAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQ 612 REI ++L H I++L++V++T S I+ VMEY+ GGELFD + K G+L E + + FQQ Sbjct: 63 REIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQ 122 Query: 613 LISAVD 630 ++S VD Sbjct: 123 ILSGVD 128
>AAPK1_MOUSE (Q5EG47) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMPK alpha-1 chain) Length = 548 Score = 105 bits (263), Expect = 8e-23 Identities = 49/126 (38%), Positives = 83/126 (65%) Frame = +1 Query: 253 EGMENSGKIVMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVR 432 E ++ G++ +G Y LG LG G FGKV K+ + VA+K+++++ + + + ++R Sbjct: 3 EKQKHDGRVKIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIR 62 Query: 433 REITTMRLVAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQ 612 REI ++L H I++L++V++T S I+ VMEY+ GGELFD + K G+L E + + FQQ Sbjct: 63 REIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQ 122 Query: 613 LISAVD 630 ++S VD Sbjct: 123 ILSGVD 128
>KIN10_ARATH (Q38997) SNF1-related protein kinase catalytic alpha subunit KIN10| (EC 2.7.11.1) (AKIN10) (AKIN alpha2) Length = 535 Score = 105 bits (261), Expect = 1e-22 Identities = 51/125 (40%), Positives = 82/125 (65%) Frame = +1 Query: 256 GMENSGKIVMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRR 435 G + + ++ Y+LGR LG G+FG+V A++ + VAIK++++ + + + E+VRR Sbjct: 30 GSRSGVESILPNYKLGRTLGIGSFGRVKIAEHALTGHKVAIKILNRRKIKNMEMEEKVRR 89 Query: 436 EITTMRLVAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQL 615 EI +RL H I++L+EV+ T + IY VMEY+ GELFD + + G+L E A +FQQ+ Sbjct: 90 EIKILRLFMHPHIIRLYEVIETPTDIYLVMEYVNSGELFDYIVEKGRLQEDEARNFFQQI 149 Query: 616 ISAVD 630 IS V+ Sbjct: 150 ISGVE 154
>AAPK2_RAT (Q09137) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMPK alpha-2 chain) Length = 552 Score = 102 bits (254), Expect = 9e-22 Identities = 46/126 (36%), Positives = 83/126 (65%) Frame = +1 Query: 253 EGMENSGKIVMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVR 432 E ++ G++ +G Y LG LG G FGKV ++ + VA+K+++++ + + + +++ Sbjct: 3 EKQKHDGRVKIGHYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIK 62 Query: 433 REITTMRLVAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQ 612 REI ++L H I++L++V++T + + VMEY+ GGELFD + K G++ E A + FQQ Sbjct: 63 REIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEVEARRLFQQ 122 Query: 613 LISAVD 630 ++SAVD Sbjct: 123 ILSAVD 128
>AAPK2_PONPY (Q5RD00) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMPK alpha-2 chain) Length = 552 Score = 102 bits (254), Expect = 9e-22 Identities = 46/126 (36%), Positives = 83/126 (65%) Frame = +1 Query: 253 EGMENSGKIVMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVR 432 E ++ G++ +G Y LG LG G FGKV ++ + VA+K+++++ + + + +++ Sbjct: 3 EKQKHDGRVKIGHYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIK 62 Query: 433 REITTMRLVAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQ 612 REI ++L H I++L++V++T + + VMEY+ GGELFD + K G++ E A + FQQ Sbjct: 63 REIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQ 122 Query: 613 LISAVD 630 ++SAVD Sbjct: 123 ILSAVD 128
>AAPK2_PIG (Q28948) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMPK alpha-2 chain) Length = 552 Score = 102 bits (254), Expect = 9e-22 Identities = 46/126 (36%), Positives = 83/126 (65%) Frame = +1 Query: 253 EGMENSGKIVMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVR 432 E ++ G++ +G Y LG LG G FGKV ++ + VA+K+++++ + + + +++ Sbjct: 3 EKQKHDGRVKIGHYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIK 62 Query: 433 REITTMRLVAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQ 612 REI ++L H I++L++V++T + + VMEY+ GGELFD + K G++ E A + FQQ Sbjct: 63 REIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQ 122 Query: 613 LISAVD 630 ++SAVD Sbjct: 123 ILSAVD 128
>AAPK2_HUMAN (P54646) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMPK alpha-2 chain) Length = 552 Score = 102 bits (254), Expect = 9e-22 Identities = 46/126 (36%), Positives = 83/126 (65%) Frame = +1 Query: 253 EGMENSGKIVMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVR 432 E ++ G++ +G Y LG LG G FGKV ++ + VA+K+++++ + + + +++ Sbjct: 3 EKQKHDGRVKIGHYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIK 62 Query: 433 REITTMRLVAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQ 612 REI ++L H I++L++V++T + + VMEY+ GGELFD + K G++ E A + FQQ Sbjct: 63 REIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQ 122 Query: 613 LISAVD 630 ++SAVD Sbjct: 123 ILSAVD 128
>AAPK2_CAEEL (Q95ZQ4) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMP-activated kinase 2) Length = 626 Score = 97.4 bits (241), Expect = 3e-20 Identities = 48/130 (36%), Positives = 80/130 (61%) Frame = +1 Query: 241 TYTLEGMENSGKIVMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLA 420 T T + E +I +G Y L LG G FGKV + + VA+K+++++ + + + Sbjct: 70 TSTKQQQELKAQIKIGHYILKETLGVGTFGKVKVGIHETTQYKVAVKILNRQKIKSLDVV 129 Query: 421 EQVRREITTMRLVAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHK 600 ++RREI + L H I++L++V++T S I+ +ME++ GGELFD + K G+L A + Sbjct: 130 GKIRREIQNLSLFRHPHIIRLYQVISTPSDIFMIMEHVSGGELFDYIVKHGRLKTAEARR 189 Query: 601 YFQQLISAVD 630 +FQQ+IS VD Sbjct: 190 FFQQIISGVD 199
>SNF1_CANAL (P52497) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 620 Score = 95.1 bits (235), Expect = 1e-19 Identities = 45/116 (38%), Positives = 85/116 (73%) Frame = +1 Query: 283 MGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVA 462 +GRY++ + LG+G+FGKV A++L + + VA+K+++++T+ K + +V REI+ +RL+ Sbjct: 50 IGRYQILKTLGEGSFGKVKLAQHLGTGQKVALKIINRKTLAKSDMQGRVEREISYLRLLR 109 Query: 463 HKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAVD 630 H I++L++V+ ++ +I V+E+ G ELFD + + GK+ E A ++FQQ+I+AV+ Sbjct: 110 HPHIIKLYDVIKSKDEIIMVIEF-AGKELFDYIVQRGKMPEDEARRFFQQIIAAVE 164
>SNF1_CANTR (O94168) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 619 Score = 94.0 bits (232), Expect = 3e-19 Identities = 44/116 (37%), Positives = 85/116 (73%) Frame = +1 Query: 283 MGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVA 462 +GRY++ + LG+G+FGKV A+++ + + VA+K+++++T+ K + +V REI+ +RL+ Sbjct: 49 IGRYQIIKTLGEGSFGKVKLAQHVGTGQKVALKIINRKTLAKSDMQGRVEREISYLRLLR 108 Query: 463 HKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAVD 630 H I++L++V+ ++ +I V+E+ G ELFD + + GK+ E A ++FQQ+I+AV+ Sbjct: 109 HPHIIKLYDVIKSKDEIIMVIEF-AGKELFDYIVQRGKMPEDEARRFFQQIIAAVE 163
>SNF1_CANGA (Q00372) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 612 Score = 92.0 bits (227), Expect = 1e-18 Identities = 43/116 (37%), Positives = 82/116 (70%) Frame = +1 Query: 283 MGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVA 462 +G Y++ + LG+G+FGKV A ++ + + VA+K+++K+ + K + ++ REI+ +RL+ Sbjct: 36 VGNYQIVKTLGEGSFGKVKLAYHVTTGQKVALKIINKKVLAKSDMQGRIEREISYLRLLR 95 Query: 463 HKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAVD 630 H I++L++V+ ++ +I V+EY G ELFD + + K++E A ++FQQ+ISAV+ Sbjct: 96 HPHIIKLYDVIKSKDEIIMVIEY-AGNELFDYIVQRNKMSEQEARRFFQQIISAVE 150
>SN1L2_MOUSE (Q8CFH6) Serine/threonine-protein kinase SNF1-like kinase 2 (EC| 2.7.11.1) (Salt-inducible kinase 2) Length = 931 Score = 92.0 bits (227), Expect = 1e-18 Identities = 47/120 (39%), Positives = 76/120 (63%) Frame = +1 Query: 271 GKIVMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTM 450 G + +G Y++ LGKG F V ++ + VAIK++DK + V L E++ RE+ M Sbjct: 13 GPVRVGFYDIEGTLGKGNFAVVKLGRHRTTKTEVAIKIIDKSQLDAVNL-EKIYREVQIM 71 Query: 451 RLVAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAVD 630 +++ H I++L++VM T+S +Y V EY K GE+FD ++ G+L E A + F Q++SAVD Sbjct: 72 KMLDHPHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVD 131
>SN1L2_PONPY (Q5REX1) Serine/threonine-protein kinase SNF1-like kinase 2 (EC| 2.7.11.1) Length = 925 Score = 91.3 bits (225), Expect = 2e-18 Identities = 47/120 (39%), Positives = 76/120 (63%) Frame = +1 Query: 271 GKIVMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTM 450 G + +G Y++ LGKG F V ++ + VAIK++DK + V L E++ RE+ M Sbjct: 13 GPVRVGFYDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKSQLDAVNL-EKIYREVQIM 71 Query: 451 RLVAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAVD 630 +++ H I++L++VM T+S +Y V EY K GE+FD ++ G+L E A + F Q++SAVD Sbjct: 72 KMLDHPHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVD 131
>SN1L2_HUMAN (Q9H0K1) Serine/threonine-protein kinase SNF1-like kinase 2 (EC| 2.7.11.1) (Qin-induced kinase) Length = 926 Score = 91.3 bits (225), Expect = 2e-18 Identities = 47/120 (39%), Positives = 76/120 (63%) Frame = +1 Query: 271 GKIVMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTM 450 G + +G Y++ LGKG F V ++ + VAIK++DK + V L E++ RE+ M Sbjct: 13 GPVRVGFYDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKSQLDAVNL-EKIYREVQIM 71 Query: 451 RLVAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAVD 630 +++ H I++L++VM T+S +Y V EY K GE+FD ++ G+L E A + F Q++SAVD Sbjct: 72 KMLDHPHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVD 131
>SNF1_YEAST (P06782) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 633 Score = 90.9 bits (224), Expect = 3e-18 Identities = 43/116 (37%), Positives = 81/116 (69%) Frame = +1 Query: 283 MGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVA 462 +G Y++ + LG+G+FGKV A + + + VA+K+++K+ + K + ++ REI+ +RL+ Sbjct: 52 IGNYQIVKTLGEGSFGKVKLAYHTTTGQKVALKIINKKVLAKSDMQGRIEREISYLRLLR 111 Query: 463 HKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAVD 630 H I++L++V+ ++ +I V+EY G ELFD + + K++E A ++FQQ+ISAV+ Sbjct: 112 HPHIIKLYDVIKSKDEIIMVIEY-AGNELFDYIVQRDKMSEQEARRFFQQIISAVE 166
>SN1L1_RAT (Q9R1U5) Serine/threonine-protein kinase SNF1-like kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase SNF1LK) (Salt-inducible protein kinase) (Protein kinase KID2) Length = 776 Score = 89.7 bits (221), Expect = 6e-18 Identities = 51/140 (36%), Positives = 84/140 (60%) Frame = +1 Query: 211 VVATRILLAVTYTLEGMENSGKIVMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMD 390 V+ + T T +G + ++ G Y++ R LGKG F V A++ + VAIK++D Sbjct: 2 VIMSEFSAVPTGTGQGQQKPLRV--GFYDVERTLGKGNFAVVKLARHRVTKTQVAIKIID 59 Query: 391 KETVLKVGLAEQVRREITTMRLVAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKA 570 K T L E++ RE+ M+L+ H +I++L++VM T+ +Y V E+ K GE+FD ++ Sbjct: 60 K-TRLDSSNLEKIYREVQLMKLLNHPNIIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSN 118 Query: 571 GKLTEGAAHKYFQQLISAVD 630 G L+E A K F Q++SAV+ Sbjct: 119 GHLSENEARKKFWQILSAVE 138
>SN1L1_HUMAN (P57059) Serine/threonine-protein kinase SNF1-like kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase SNF1LK) Length = 783 Score = 89.7 bits (221), Expect = 6e-18 Identities = 48/126 (38%), Positives = 77/126 (61%) Frame = +1 Query: 253 EGMENSGKIVMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVR 432 +G + +G Y++ R LGKG F V A++ + VAIK++DK T L E++ Sbjct: 14 QGQGQQKPLRVGFYDIERTLGKGNFAVVKLARHRVTKTQVAIKIIDK-TRLDSSNLEKIY 72 Query: 433 REITTMRLVAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQ 612 RE+ M+L+ H I++L++VM T+ +Y V E+ K GE+FD ++ G L+E A K F Q Sbjct: 73 REVQLMKLLNHPHIIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQ 132 Query: 613 LISAVD 630 ++SAV+ Sbjct: 133 ILSAVE 138
>MARK1_MOUSE (Q8VHJ5) Serine/threonine-protein kinase MARK1 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 1) (ELKL motif serine/threonine-protein kinase 3) Length = 795 Score = 89.4 bits (220), Expect = 8e-18 Identities = 46/115 (40%), Positives = 74/115 (64%) Frame = +1 Query: 283 MGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVA 462 +G Y L + +GKG F KV A+++ + R VA+K++DK T L +++ RE+ M+++ Sbjct: 57 IGNYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDK-TQLNPTSLQKLFREVRIMKILN 115 Query: 463 HKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 H +IV+L EV+ T +Y VMEY GGE+FD + G++ E A F+Q++SAV Sbjct: 116 HPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAV 170
>MARK1_HUMAN (Q9P0L2) Serine/threonine-protein kinase MARK1 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 1) Length = 795 Score = 89.4 bits (220), Expect = 8e-18 Identities = 46/115 (40%), Positives = 74/115 (64%) Frame = +1 Query: 283 MGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVA 462 +G Y L + +GKG F KV A+++ + R VA+K++DK T L +++ RE+ M+++ Sbjct: 57 IGNYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDK-TQLNPTSLQKLFREVRIMKILN 115 Query: 463 HKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 H +IV+L EV+ T +Y VMEY GGE+FD + G++ E A F+Q++SAV Sbjct: 116 HPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAV 170
>MARK1_RAT (O08678) Serine/threonine-protein kinase MARK1 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 1) Length = 793 Score = 89.4 bits (220), Expect = 8e-18 Identities = 46/115 (40%), Positives = 74/115 (64%) Frame = +1 Query: 283 MGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVA 462 +G Y L + +GKG F KV A+++ + R VA+K++DK T L +++ RE+ M+++ Sbjct: 57 IGNYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDK-TQLNPTSLQKLFREVRIMKILN 115 Query: 463 HKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 H +IV+L EV+ T +Y VMEY GGE+FD + G++ E A F+Q++SAV Sbjct: 116 HPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAV 170
>SN1L2_CHICK (Q9IA88) Serine/threonine-protein kinase SNF1-like kinase 2 (EC| 2.7.11.1) (Qin-induced kinase) Length = 798 Score = 89.4 bits (220), Expect = 8e-18 Identities = 47/116 (40%), Positives = 74/116 (63%) Frame = +1 Query: 283 MGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVA 462 +G Y++ R LGKG F V A++ + VAIK++DK T L E++ RE+ M+L+ Sbjct: 23 VGFYDIERTLGKGNFAVVKLARHRVTKTQVAIKIIDK-TRLDPSNLEKIYREVQIMKLLN 81 Query: 463 HKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAVD 630 H I++L++VM T+ +Y V E+ K GE+FD ++ G L+E A K F Q++SAV+ Sbjct: 82 HPHIIKLYQVMETKDMLYIVTEFAKNGEMFDHLTSNGHLSESEARKKFWQILSAVE 137
>MARK3_MOUSE (Q03141) MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1)| (MPK-10) (ELKL motif kinase 2) Length = 753 Score = 89.0 bits (219), Expect = 1e-17 Identities = 46/115 (40%), Positives = 74/115 (64%) Frame = +1 Query: 283 MGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVA 462 +G Y L + +GKG F KV A+++ + R VAIK++DK T L +++ RE+ M+++ Sbjct: 53 IGNYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDK-TQLNPTSLQKLFREVRIMKILN 111 Query: 463 HKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 H +IV+L EV+ T +Y +MEY GGE+FD + G++ E A F+Q++SAV Sbjct: 112 HPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAV 166
>MARK3_RAT (Q8VHF0) MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1)| Length = 797 Score = 89.0 bits (219), Expect = 1e-17 Identities = 46/115 (40%), Positives = 74/115 (64%) Frame = +1 Query: 283 MGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVA 462 +G Y L + +GKG F KV A+++ + R VAIK++DK T L +++ RE+ M+++ Sbjct: 53 IGNYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDK-TQLNPTSLQKLFREVRIMKILN 111 Query: 463 HKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 H +IV+L EV+ T +Y +MEY GGE+FD + G++ E A F+Q++SAV Sbjct: 112 HPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAV 166
>MARK2_RAT (O08679) Serine/threonine-protein kinase MARK2 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 2) (ELKL Motif Kinase) (EMK1) Length = 722 Score = 88.2 bits (217), Expect = 2e-17 Identities = 45/115 (39%), Positives = 74/115 (64%) Frame = +1 Query: 283 MGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVA 462 +G Y L + +GKG F KV A+++ + + VA+K++DK T L +++ RE+ M+++ Sbjct: 50 IGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDK-TQLNSSSLQKLFREVRIMKVLN 108 Query: 463 HKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 H +IV+L EV+ T +Y VMEY GGE+FD + G++ E A F+Q++SAV Sbjct: 109 HPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAV 163
>MARK2_HUMAN (Q7KZI7) Serine/threonine-protein kinase MARK2 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 2) (ELKL motif kinase) (EMK1) (PAR1 homolog) Length = 788 Score = 88.2 bits (217), Expect = 2e-17 Identities = 45/115 (39%), Positives = 74/115 (64%) Frame = +1 Query: 283 MGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVA 462 +G Y L + +GKG F KV A+++ + + VA+K++DK T L +++ RE+ M+++ Sbjct: 50 IGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDK-TQLNSSSLQKLFREVRIMKVLN 108 Query: 463 HKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 H +IV+L EV+ T +Y VMEY GGE+FD + G++ E A F+Q++SAV Sbjct: 109 HPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAV 163
>BRSK1_HUMAN (Q8TDC3) BR serine/threonine-protein kinase 1 (EC 2.7.11.1) (SAD1| kinase) (SAD1A) Length = 794 Score = 88.2 bits (217), Expect = 2e-17 Identities = 44/116 (37%), Positives = 74/116 (63%) Frame = +1 Query: 283 MGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVA 462 +G Y L + LGKG G V + + + VAIK++++E L + +V REI ++L+ Sbjct: 47 VGPYRLEKTLGKGQTGLVKLGVHCITGQKVAIKIVNREK-LSESVLMKVEREIAILKLIE 105 Query: 463 HKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAVD 630 H +++LH+V + +Y V+E++ GGELFD + K G+LT A K+F+Q++SA+D Sbjct: 106 HPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALD 161
>BRSK2_HUMAN (Q8IWQ3) BR serine/threonine-protein kinase 2 (EC 2.7.11.1)| (Serine/threonine-protein kinase 29) (SAD1B) Length = 736 Score = 87.8 bits (216), Expect = 2e-17 Identities = 45/116 (38%), Positives = 74/116 (63%) Frame = +1 Query: 283 MGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVA 462 +G Y L + LGKG G V + + + VAIK++++E L + +V REI ++L+ Sbjct: 16 VGPYRLEKTLGKGQTGLVKLGVHCVTCQKVAIKIVNREK-LSESVLMKVEREIAILKLIE 74 Query: 463 HKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAVD 630 H +++LH+V + +Y V+E++ GGELFD + K G+LT A K+F+Q+ISA+D Sbjct: 75 HPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALD 130
>SN1L1_MOUSE (Q60670) Serine/threonine-protein kinase SNF1-like kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase SNF1LK) (HRT-20) (Myocardial SNF1-like kinase) Length = 779 Score = 87.8 bits (216), Expect = 2e-17 Identities = 46/116 (39%), Positives = 75/116 (64%) Frame = +1 Query: 283 MGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVA 462 +G Y++ R LGKG F V A++ + VAIK++DK T L E++ RE+ M+L+ Sbjct: 24 VGFYDVERTLGKGNFAVVKLARHRVTKTQVAIKIIDK-TRLDSSNLEKIYREVQLMKLLN 82 Query: 463 HKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAVD 630 H +I++L++VM T+ +Y V E+ K GE+FD ++ G L+E A + F Q++SAV+ Sbjct: 83 HPNIIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARQKFWQILSAVE 138
>MARK4_MOUSE (Q8CIP4) MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1)| Length = 752 Score = 87.0 bits (214), Expect = 4e-17 Identities = 47/115 (40%), Positives = 72/115 (62%) Frame = +1 Query: 283 MGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVA 462 +G Y L R +GKG F KV A+++ + R VAIK++DK T L +++ RE+ M+ + Sbjct: 56 VGNYRLLRTIGKGNFAKVKLARHILTGREVAIKIIDK-TQLNPSSLQKLFREVRIMKGLN 114 Query: 463 HKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 H +IV+L EV+ T +Y VMEY GE+FD + G++ E A F+Q++SAV Sbjct: 115 HPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAV 169
>MARK4_HUMAN (Q96L34) MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase-like 1) Length = 752 Score = 87.0 bits (214), Expect = 4e-17 Identities = 47/115 (40%), Positives = 72/115 (62%) Frame = +1 Query: 283 MGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVA 462 +G Y L R +GKG F KV A+++ + R VAIK++DK T L +++ RE+ M+ + Sbjct: 56 VGNYRLLRTIGKGNFAKVKLARHILTGREVAIKIIDK-TQLNPSSLQKLFREVRIMKGLN 114 Query: 463 HKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 H +IV+L EV+ T +Y VMEY GE+FD + G++ E A F+Q++SAV Sbjct: 115 HPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAV 169
>AAPK1_CAEEL (P45894) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMP-activated kinase 1) Length = 589 Score = 85.1 bits (209), Expect = 2e-16 Identities = 41/123 (33%), Positives = 73/123 (59%) Frame = +1 Query: 259 MENSGKIVMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRRE 438 + +G + +G + + +GKGAFG V ++++ VAIK++++ + +G + R E Sbjct: 13 LAGTGHLKIGNFVIKETIGKGAFGAVKRGTHIQTGYDVAIKILNRGRMKGLGTVNKTRNE 72 Query: 439 ITTMRLVAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLI 618 I ++ + H I +L V++T S I+ VME + GGELF +++ G L + +YFQQ+I Sbjct: 73 IDNLQKLTHPHITRLFRVISTPSDIFLVMELVSGGELFSYITRKGALPIRESRRYFQQII 132 Query: 619 SAV 627 S V Sbjct: 133 SGV 135
>NUAK1_HUMAN (O60285) NUAK family, SNF1-like kinase 1 (EC 2.7.11.1)| (AMPK-related protein kinase 5) Length = 661 Score = 84.7 bits (208), Expect = 2e-16 Identities = 45/113 (39%), Positives = 65/113 (57%) Frame = +1 Query: 289 RYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHK 468 RYEL LGKG +GKV A S R VAIK + K+ + +RREI M + H Sbjct: 54 RYELQETLGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDEQDMVHIRREIEIMSSLNHP 113 Query: 469 SIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 I+ ++EV + KI +MEY GEL+D +S+ +L+E +F+Q++SAV Sbjct: 114 HIISIYEVFENKDKIVIIMEYASKGELYDYISERRRLSERETRHFFRQIVSAV 166
>SNF1_SCHPO (O74536) SNF1-like protein kinase ssp2 (EC 2.7.11.1)| Length = 576 Score = 84.3 bits (207), Expect = 3e-16 Identities = 41/116 (35%), Positives = 76/116 (65%) Frame = +1 Query: 283 MGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVA 462 +G Y + LG+G+FGKV A + ++ + VA+K + ++ + K + +V REI+ ++L+ Sbjct: 31 IGPYIIRETLGEGSFGKVKLATHYKTQQKVALKFISRQLLKKSDMHMRVEREISYLKLLR 90 Query: 463 HKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAVD 630 H I++L++V+ T + I V+EY GGELFD + + ++TE ++FQQ+I A++ Sbjct: 91 HPHIIKLYDVITTPTDIVMVIEY-AGGELFDYIVEKKRMTEDEGRRFFQQIICAIE 145
>NUAK1_MOUSE (Q641K5) NUAK family, SNF1-like kinase 1 (EC 2.7.11.1)| Length = 658 Score = 84.0 bits (206), Expect = 3e-16 Identities = 45/113 (39%), Positives = 65/113 (57%) Frame = +1 Query: 289 RYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHK 468 RYEL LGKG +GKV A S R VAIK + K+ + +RREI M + H Sbjct: 55 RYELQETLGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDELDMVHIRREIEIMSSLNHP 114 Query: 469 SIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 I+ ++EV + KI +MEY GEL+D +S+ +L+E +F+Q++SAV Sbjct: 115 HIISIYEVFENKDKIVIIMEYASKGELYDYISERRRLSERETRHFFRQIVSAV 167
>MARK2_MOUSE (Q05512) Serine/threonine-protein kinase MARK2 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 2) (ELKL Motif Kinase) (EMK1) Length = 776 Score = 83.6 bits (205), Expect = 4e-16 Identities = 42/112 (37%), Positives = 71/112 (63%) Frame = +1 Query: 283 MGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVA 462 +G Y L + +GKG F KV A+++ + + VA+K++DK T L +++ RE+ M+++ Sbjct: 50 IGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDK-TQLNSSSLQKLFREVRIMKVLN 108 Query: 463 HKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLI 618 H +IV+L EV+ T +Y VMEY GGE+FD + G++ E A F+Q++ Sbjct: 109 HPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIV 160
>MARK3_HUMAN (P27448) MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1)| (Cdc25C-associated protein kinase 1) (cTAK1) (C-TAK1) (Serine/threonine protein kinase p78) (Ser/Thr protein kinase PAR-1) (Protein kinase STK10) Length = 776 Score = 82.8 bits (203), Expect = 8e-16 Identities = 43/110 (39%), Positives = 69/110 (62%) Frame = +1 Query: 283 MGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVA 462 +G Y L + +GKG F KV A+++ + R VAIK++DK T L +++ RE+ M+++ Sbjct: 53 IGNYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDK-TQLNPTSLQKLFREVRIMKILN 111 Query: 463 HKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQ 612 H +IV+L EV+ T +Y +MEY GGE+FD + G++ E A F+Q Sbjct: 112 HPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQ 161
>KKK1_YEAST (P34244) Probable serine/threonine-protein kinase YKL101W (EC| 2.7.11.1) Length = 1518 Score = 82.4 bits (202), Expect = 1e-15 Identities = 49/165 (29%), Positives = 83/165 (50%), Gaps = 35/165 (21%) Frame = +1 Query: 238 VTYTLEGMENSGKIVMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKE------- 396 V+ + + + +G ++LG+ LGKG+ G+V AKN+E+ + AIK++ K+ Sbjct: 63 VSVATKSSKRKSRDTVGPWKLGKTLGKGSSGRVRLAKNMETGQLAAIKIVPKKKAFVHCS 122 Query: 397 ----------------TVLKVGLAEQ------------VRREITTMRLVAHKSIVQLHEV 492 V +A + + REI M+L++H +++ L EV Sbjct: 123 NNGTVPNSYSSSMVTSNVSSPSIASREHSNHSQTNPYGIEREIVIMKLISHTNVMALFEV 182 Query: 493 MATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 +S++Y V+EY+ GGELFD + GKL E A YF+Q++ V Sbjct: 183 WENKSELYLVLEYVDGGELFDYLVSKGKLPEREAIHYFKQIVEGV 227
>SAPK9_ORYSA (Q75V57) Serine/threonine-protein kinase SAPK9 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 9) Length = 361 Score = 82.0 bits (201), Expect = 1e-15 Identities = 45/113 (39%), Positives = 66/113 (58%) Frame = +1 Query: 289 RYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHK 468 RYEL + +G G FG +N S VA+K +D+ + E V+REI R + H Sbjct: 21 RYELVKEIGSGNFGVARLMRNRASGDLVAVKYIDRGEKID----ENVQREIINHRSLRHP 76 Query: 469 SIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 +I++ EV+ T + + VMEY GGELF+++ AG+ +E A +FQQLIS V Sbjct: 77 NIIRFKEVILTPTHLAIVMEYASGGELFERICSAGRFSEDEARFFFQQLISGV 129
>RKIN1_SECCE (Q02723) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 502 Score = 81.6 bits (200), Expect = 2e-15 Identities = 43/116 (37%), Positives = 72/116 (62%), Gaps = 3/116 (2%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRL---VA 462 Y LG++LG G F KV A++ + VAIK++++ + + E+ +REI +RL + Sbjct: 14 YYLGKILGVGTFAKVIIAEHKHTRHKVAIKVLNRRQMRAPEMEEKAKREIKILRLFIDLI 73 Query: 463 HKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAVD 630 H I++++EV+ T I+ VMEY + G+L D + + +L E A + FQQ+ISAV+ Sbjct: 74 HPHIIRVYEVIVTPKDIFVVMEYCQNGDLLDYILEKRRLQEDEARRTFQQIISAVE 129
>SAPK1_ORYSA (Q75LR7) Serine/threonine-protein kinase SAPK1 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 1) Length = 342 Score = 81.3 bits (199), Expect = 2e-15 Identities = 45/115 (39%), Positives = 70/115 (60%) Frame = +1 Query: 283 MGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVA 462 M RYE+ R +G G FG +++ +N A+K +++ LK+ E V+REI R + Sbjct: 1 MERYEVMRDIGSGNFGVAKLVRDVATNHLFAVKFIERG--LKID--EHVQREIMNHRSLK 56 Query: 463 HKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 H +I++ EV+ T + + VMEY GGELF+++ AG+ +E A +FQQLIS V Sbjct: 57 HPNIIRFKEVVLTPTHLAIVMEYAAGGELFERICNAGRFSEDEARFFFQQLISGV 111
>SNRK_HUMAN (Q9NRH2) SNF-related serine/threonine-protein kinase (EC 2.7.11.1)| (SNF1-related kinase) Length = 765 Score = 81.3 bits (199), Expect = 2e-15 Identities = 46/120 (38%), Positives = 76/120 (63%), Gaps = 1/120 (0%) Frame = +1 Query: 271 GKIVMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTM 450 GKI G Y+L + LG+G F V A+++ + VA+K++DK T L + +E+ M Sbjct: 10 GKIA-GLYDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDK-TKLDTLATGHLFQEVRCM 67 Query: 451 RLVAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGK-LTEGAAHKYFQQLISAV 627 +LV H +IV+L+EV+ T++K+Y ++E GG++FD + K + L E A KYF Q++ A+ Sbjct: 68 KLVQHPNIVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAI 127
>SNRK_RAT (Q63553) SNF-related serine/threonine-protein kinase (EC 2.7.11.1)| (SNF1-related kinase) Length = 746 Score = 81.3 bits (199), Expect = 2e-15 Identities = 46/120 (38%), Positives = 76/120 (63%), Gaps = 1/120 (0%) Frame = +1 Query: 271 GKIVMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTM 450 GKI G Y+L + LG+G F V A+++ + VA+K++DK T L + +E+ M Sbjct: 10 GKIA-GLYDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDK-TKLDTLATGHLFQEVRCM 67 Query: 451 RLVAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGK-LTEGAAHKYFQQLISAV 627 +LV H +IV+L+EV+ T++K+Y ++E GG++FD + K + L E A KYF Q++ A+ Sbjct: 68 KLVQHPNIVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAI 127
>SNRK_MOUSE (Q8VDU5) SNF-related serine/threonine-protein kinase (EC 2.7.11.1)| (SNF1-related kinase) Length = 748 Score = 81.3 bits (199), Expect = 2e-15 Identities = 46/120 (38%), Positives = 76/120 (63%), Gaps = 1/120 (0%) Frame = +1 Query: 271 GKIVMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTM 450 GKI G Y+L + LG+G F V A+++ + VA+K++DK T L + +E+ M Sbjct: 10 GKIA-GLYDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDK-TKLDTLATGHLFQEVRCM 67 Query: 451 RLVAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGK-LTEGAAHKYFQQLISAV 627 +LV H +IV+L+EV+ T++K+Y ++E GG++FD + K + L E A KYF Q++ A+ Sbjct: 68 KLVQHPNIVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAI 127
>AURKB_RAT (O55099) Serine/threonine-protein kinase 12 (EC 2.7.11.1) (Aurora-| and Ipl1-like midbody-associated protein 1) (AIM-1) (Aurora-B) Length = 343 Score = 81.3 bits (199), Expect = 2e-15 Identities = 41/126 (32%), Positives = 71/126 (56%) Frame = +1 Query: 250 LEGMENSGKIVMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQV 429 L+G ++ + +E+GR LGKG FG V+ A+ +S VA+K++ K + K G+ Q+ Sbjct: 66 LQGSQSRQPFTIDNFEIGRPLGKGKFGNVYLAREKKSRFIVALKILFKSQIEKEGVEHQL 125 Query: 430 RREITTMRLVAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQ 609 RREI + H +I+QL+ + +IY ++EY GEL+ ++ K+G E + Sbjct: 126 RREIEIQAHLKHPNILQLYNYFYDQQRIYLILEYAPRGELYKELQKSGTFDEQRTATIME 185 Query: 610 QLISAV 627 +L A+ Sbjct: 186 ELSDAL 191
>SAPK7_ORYSA (Q7XQP4) Serine/threonine-protein kinase SAPK7 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 7) Length = 359 Score = 80.5 bits (197), Expect = 4e-15 Identities = 47/115 (40%), Positives = 67/115 (58%) Frame = +1 Query: 283 MGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVA 462 M RYEL + +G G FG +N E+ VA+K + + LK+ E V REI R + Sbjct: 1 MERYELLKDIGAGNFGVARLMRNKETKELVAMKYIPRG--LKID--ENVAREIINHRSLR 56 Query: 463 HKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 H +I++ EV+ T + + VMEY GGELFD++ AG+ +E A +FQQLI V Sbjct: 57 HPNIIRFKEVVVTPTHLAIVMEYAAGGELFDRICNAGRFSEDEARYFFQQLICGV 111
>ICL1_KLULA (Q6CWQ4) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 361 Score = 79.7 bits (195), Expect = 6e-15 Identities = 38/113 (33%), Positives = 67/113 (59%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHKS 471 +E+G++LGKG FGKV+ K+ E+ A+K M+K+ +++ + +Q RRE+ HK+ Sbjct: 100 FEIGKILGKGKFGKVYCVKHRETGLICALKAMEKKEIVQYTIQKQFRREVEIQGSFKHKN 159 Query: 472 IVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAVD 630 + QL+ ++Y +MEY+ GEL+ + G L E A + Q+ +A+D Sbjct: 160 LTQLYGFFYDEKRVYLLMEYVYYGELYKFLKNNGPLNETLASYFVYQMANALD 212
>MELK_HUMAN (Q14680) Maternal embryonic leucine zipper kinase (EC 2.7.11.1)| (hMELK) (Protein kinase PK38) (hPK38) Length = 651 Score = 79.7 bits (195), Expect = 6e-15 Identities = 43/112 (38%), Positives = 67/112 (59%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHKS 471 YEL +G G F KV A ++ + VAIK+MDK T+ +++ EI ++ + H+ Sbjct: 11 YELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTLGSD--LPRIKTEIEALKNLRHQH 68 Query: 472 IVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 I QL+ V+ T +KI+ V+EY GGELFD + +L+E F+Q++SAV Sbjct: 69 ICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAV 120
>STK6_XENLA (Q91820) Serine/threonine-protein kinase Eg2 (EC 2.7.11.1) (pEg2)| (p46Eg265) Length = 407 Score = 79.3 bits (194), Expect = 8e-15 Identities = 38/112 (33%), Positives = 67/112 (59%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHKS 471 +E+GR LGKG FG V+ A+ ES +A+K++ K + K G+ Q+RRE+ + H + Sbjct: 140 FEIGRPLGKGKFGNVYLARERESKFILALKVLFKSQLEKAGVEHQLRREVEIQSHLRHPN 199 Query: 472 IVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 I++L+ S++Y +++Y GGELF ++ K + + + Y +QL A+ Sbjct: 200 ILRLYGYFHDASRVYLILDYAPGGELFRELQKCTRFDDQRSAMYIKQLAEAL 251
>ARK1_SCHPO (O59790) Serine/threonine-protein kinase ark1 (EC 2.7.11.1)| (Aurora-related kinase 1) Length = 355 Score = 79.3 bits (194), Expect = 8e-15 Identities = 39/115 (33%), Positives = 71/115 (61%) Frame = +1 Query: 283 MGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVA 462 +G +E+G+ LGKG FG+V+ AK ++ VA+K + K +++ + +QVRREI + Sbjct: 86 IGMFEIGKPLGKGKFGRVYLAKEKKTGFIVALKTLHKSELVQSKIEKQVRREIEIQSNLR 145 Query: 463 HKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 HK+I++L+ +IY ++E+ GEL+ + +A + +E A KY Q+ +A+ Sbjct: 146 HKNILRLYGHFHDEKRIYLILEFAGRGELYQHLRRAKRFSEEVASKYIFQMANAL 200
>AURKB_MOUSE (O70126) Serine/threonine-protein kinase 12 (EC 2.7.11.1)| (Aurora-related kinase 2) (Serine/threonine-protein kinase 5) (STK-1) (Aurora-B) Length = 345 Score = 79.0 bits (193), Expect = 1e-14 Identities = 40/125 (32%), Positives = 69/125 (55%) Frame = +1 Query: 253 EGMENSGKIVMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVR 432 +G +N + +E+GR LGKG FG V+ A+ +S VA+K++ K + K G+ Q+R Sbjct: 69 QGSQNKQPFTIDNFEIGRPLGKGKFGNVYLAREKKSRFIVALKILFKSQIEKEGVEHQLR 128 Query: 433 REITTMRLVAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQ 612 REI + H +I+QL+ + +IY ++EY GEL+ ++ K+ E ++ Sbjct: 129 REIEIQAHLKHPNILQLYNYFYDQQRIYLILEYAPRGELYKELQKSRTFDEQRTATIMEE 188 Query: 613 LISAV 627 L A+ Sbjct: 189 LSDAL 193
>STK6L_XENLA (Q91819) Serine/threonine-protein kinase Eg2-like (EC 2.7.11.1)| (p46XlEg22) Length = 408 Score = 79.0 bits (193), Expect = 1e-14 Identities = 38/112 (33%), Positives = 67/112 (59%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHKS 471 +E+GR LGKG FG V+ A+ ES +A+K++ K + K G+ Q+RRE+ + H + Sbjct: 140 FEIGRPLGKGKFGNVYLARERESKFILALKVLFKSQLEKAGVEHQLRREVEIQSHLRHPN 199 Query: 472 IVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 I++L+ S++Y +++Y GGELF ++ K + + + Y +QL A+ Sbjct: 200 ILRLYGYFHDASRVYLILDYAPGGELFRELQKCTRFDDQRSALYIKQLAEAL 251
>SAPKA_ORYSA (Q75H77) Serine/threonine-protein kinase SAPK10 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 10) Length = 362 Score = 79.0 bits (193), Expect = 1e-14 Identities = 43/113 (38%), Positives = 66/113 (58%) Frame = +1 Query: 289 RYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHK 468 RYEL R +G G FG ++ + VA+K +++ + E V+REI R + H Sbjct: 22 RYELVRDIGSGNFGVARLMRSRADGQLVAVKYIERGDKID----ENVQREIINHRSLRHP 77 Query: 469 SIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 +I++ EV+ T + + VMEY GGELF+++ AG+ +E A +FQQLIS V Sbjct: 78 NIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLISGV 130
>MELK_MOUSE (Q61846) Maternal embryonic leucine zipper kinase (EC 2.7.11.1)| (Protein kinase PK38) (mPK38) Length = 643 Score = 78.6 bits (192), Expect = 1e-14 Identities = 43/112 (38%), Positives = 67/112 (59%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHKS 471 YEL +G G F KV A ++ + VAIK+MDK + +V+ EI ++ + H+ Sbjct: 11 YELYETIGTGGFAKVKLACHVLTGEMVAIKIMDKNALGSD--LPRVKTEIDALKSLRHQH 68 Query: 472 IVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 I QL+ V+ T++KI+ V+EY GGELFD + +L+E F+Q++SAV Sbjct: 69 ICQLYHVLETKNKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQILSAV 120
>SAPK6_ORYSA (Q6ZI44) Serine/threonine-protein kinase SAPK6 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 6) Length = 365 Score = 78.2 bits (191), Expect = 2e-14 Identities = 45/115 (39%), Positives = 67/115 (58%) Frame = +1 Query: 283 MGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVA 462 M +YEL + +G G FG +N E+ VA+K + + LK+ E V REI R + Sbjct: 1 MEKYELLKDIGSGNFGVARLMRNRETKELVAMKYIPRG--LKID--ENVAREIINHRSLR 56 Query: 463 HKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 H +I++ EV+ T + + VMEY GGELFD++ AG+ +E + +FQQLI V Sbjct: 57 HPNIIRFKEVVLTPTHLAIVMEYAAGGELFDRICSAGRFSEDESRYFFQQLICGV 111
>ASK2_ARATH (P43292) Serine/threonine-protein kinase ASK2 (EC 2.7.11.1)| Length = 353 Score = 78.2 bits (191), Expect = 2e-14 Identities = 42/116 (36%), Positives = 67/116 (57%) Frame = +1 Query: 283 MGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVA 462 M +Y++ + LG G FG ++ ++ VA+K +++ + E V REI R + Sbjct: 1 MDKYDVVKDLGAGNFGVARLLRHKDTKELVAMKYIERGRKID----ENVAREIINHRSLK 56 Query: 463 HKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAVD 630 H +I++ EV+ T + + VMEY GGELFD++ AG+ +E A +FQQLI VD Sbjct: 57 HPNIIRFKEVILTPTHLAIVMEYASGGELFDRICTAGRFSEAEARYFFQQLICGVD 112
>AURKC_HUMAN (Q9UQB9) Serine/threonine-protein kinase 13 (EC 2.7.11.1)| (Aurora/Ipl1/Eg2 protein 2) (Aurora/Ipl1-related kinase 3) (Aurora-C) Length = 309 Score = 78.2 bits (191), Expect = 2e-14 Identities = 40/118 (33%), Positives = 69/118 (58%) Frame = +1 Query: 274 KIVMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMR 453 ++ + +E+GR LGKG FG V+ A+ ES+ VA+K++ K + K GL Q+RREI Sbjct: 37 RLTVDDFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQA 96 Query: 454 LVAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 + H +I++L+ ++Y ++EY GEL+ ++ K+ KL E ++L A+ Sbjct: 97 HLQHPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEELADAL 154
>IPL1_ASHGO (Q755C4) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 367 Score = 77.8 bits (190), Expect = 2e-14 Identities = 34/113 (30%), Positives = 65/113 (57%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHKS 471 +E+G++LGKG FG+V+ +++ES A+K M+K+ +++ + +Q RRE+ + H + Sbjct: 109 FEIGKVLGKGKFGRVYCVRHIESGFVCALKAMEKKDIIQYNIEKQFRREVEIQSSLRHPN 168 Query: 472 IVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAVD 630 + QL+ ++Y +MEY+ GEL+ + + A Y Q+ A+D Sbjct: 169 LTQLYGYFHDEKRVYLLMEYLVNGELYKHLKGRSHFNDVVASYYVYQMADALD 221
>AURKC_MOUSE (O88445) Serine/threonine-protein kinase 13 (EC 2.7.11.1)| (Aurora/Ipl1/Eg2 protein 1) (Aurora-C) Length = 282 Score = 77.8 bits (190), Expect = 2e-14 Identities = 38/112 (33%), Positives = 69/112 (61%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHKS 471 +E+GR LG+G FG+V+ A+ E++ VA+K++ K + K GL Q+RRE+ + H++ Sbjct: 16 FEIGRPLGRGKFGRVYLARLKENHFIVALKVLFKSEIEKEGLEHQLRREVEIQAHLQHRN 75 Query: 472 IVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 I++L+ ++IY ++EY GGEL+ ++ + KL + Q+L A+ Sbjct: 76 ILRLYNYFYDDTRIYLILEYAPGGELYKELQRHQKLDQQRTATIIQELSDAL 127
>TSSK3_MOUSE (Q9D2E1) Testis-specific serine/threonine-protein kinase 3 (EC| 2.7.11.1) (TSSK-3) (Testis-specific kinase 3) (TSK-3) (Serine/threonine-protein kinase 22C) Length = 268 Score = 77.8 bits (190), Expect = 2e-14 Identities = 41/113 (36%), Positives = 70/113 (61%), Gaps = 1/113 (0%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHKS 471 Y+LG+ +G+G + KV A + + R VAIK++DK + + + RE+ +R + HK+ Sbjct: 10 YQLGKTIGEGTYSKVKEAFSKKHQRKVAIKIIDKMGGPEEFIQRFLPRELQIVRTLDHKN 69 Query: 472 IVQLHEVMATRS-KIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 I+Q++E++ + KIY VME +GG++FD V G L E A F+Q++ A+ Sbjct: 70 IIQVYEMLESADGKIYLVMELAEGGDVFDCVLNGGPLPESRAKALFRQMVEAI 122
>SAPK2_ORYSA (Q84TC6) Serine/threonine-protein kinase SAPK2 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 2) Length = 339 Score = 77.4 bits (189), Expect = 3e-14 Identities = 42/115 (36%), Positives = 67/115 (58%) Frame = +1 Query: 283 MGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVA 462 M RYE+ + +G G FG +++ + A+K +++ + E V+REI R + Sbjct: 1 MERYEVIKDIGSGNFGVAKLVRDVRTKELFAVKFIERGQKID----ENVQREIMNHRSLR 56 Query: 463 HKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 H +IV+ EV+ T + + VMEY GGELF+++ AG+ +E A +FQQLIS V Sbjct: 57 HPNIVRFKEVVLTPTHLAIVMEYAAGGELFERICSAGRFSEDEARFFFQQLISGV 111
>HUNK_PANTR (Q68UT7) Hormonally up-regulated neu tumor-associated kinase (EC| 2.7.11.1) Length = 714 Score = 77.0 bits (188), Expect = 4e-14 Identities = 43/118 (36%), Positives = 70/118 (59%), Gaps = 2/118 (1%) Frame = +1 Query: 283 MGRYELG-RLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLK-VGLAEQVRREITTMRL 456 +G Y +G R LG+G+F KV ++ + VAIK++DK+ K + + +RRE ++ Sbjct: 58 VGNYLIGSRKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQM 117 Query: 457 VAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAVD 630 + H +I QL +++ T + Y VME GG L K+ + +L E A +Y +QLISAV+ Sbjct: 118 IRHPNITQLLDILETENSYYLVMELCPGGNLMHKIYEKKRLEESEARRYIRQLISAVE 175
>HUNK_MOUSE (O88866) Hormonally up-regulated neu tumor-associated kinase (EC| 2.7.11.1) (Serine/threonine-protein kinase MAK-V) Length = 714 Score = 77.0 bits (188), Expect = 4e-14 Identities = 43/118 (36%), Positives = 70/118 (59%), Gaps = 2/118 (1%) Frame = +1 Query: 283 MGRYELG-RLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLK-VGLAEQVRREITTMRL 456 +G Y +G R LG+G+F KV ++ + VAIK++DK+ K + + +RRE ++ Sbjct: 58 VGNYLIGSRKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQM 117 Query: 457 VAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAVD 630 + H +I QL +++ T + Y VME GG L K+ + +L E A +Y +QLISAV+ Sbjct: 118 IRHPNITQLLDILETENSYYLVMELCPGGNLMHKIYEKKRLDEAEARRYIRQLISAVE 175
>HUNK_HUMAN (P57058) Hormonally up-regulated neu tumor-associated kinase (EC| 2.7.11.1) (Serine/threonine-protein kinase MAK-V) (B19) Length = 714 Score = 77.0 bits (188), Expect = 4e-14 Identities = 43/118 (36%), Positives = 70/118 (59%), Gaps = 2/118 (1%) Frame = +1 Query: 283 MGRYELG-RLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLK-VGLAEQVRREITTMRL 456 +G Y +G R LG+G+F KV ++ + VAIK++DK+ K + + +RRE ++ Sbjct: 58 VGNYLIGSRKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQM 117 Query: 457 VAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAVD 630 + H +I QL +++ T + Y VME GG L K+ + +L E A +Y +QLISAV+ Sbjct: 118 IRHPNITQLLDILETENSYYLVMELCPGGNLMHKIYEKKRLEESEARRYIRQLISAVE 175
>PK2_DICDI (P28178) Protein kinase 2 (EC 2.7.11.1)| Length = 479 Score = 76.6 bits (187), Expect = 5e-14 Identities = 35/113 (30%), Positives = 66/113 (58%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHKS 471 +EL ++GKG+FGKV K ++ A+K++ K+ ++ + E T ++ ++H Sbjct: 153 FELLNVIGKGSFGKVMQVKKKGEDKIFAMKVLRKDAIIARKQVNHTKSEKTILQCISHPF 212 Query: 472 IVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAVD 630 IV LH T+ K+Y V++++ GGELF + + G+ +E Y +++SA+D Sbjct: 213 IVNLHYAFQTKDKLYMVLDFVNGGELFFHLKREGRFSEPRVKIYAAEIVSALD 265
>SAPK3_ORYSA (Q75V63) Serine/threonine-protein kinase SAPK3 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 3) (Protein kinase REK) Length = 334 Score = 76.6 bits (187), Expect = 5e-14 Identities = 43/113 (38%), Positives = 64/113 (56%) Frame = +1 Query: 289 RYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHK 468 RYE + LG G FG ++ S VA+K +++ + E V+REI R + H Sbjct: 4 RYEALKELGAGNFGVARLVRDKRSKELVAVKYIERGKKID----ENVQREIINHRSLRHP 59 Query: 469 SIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 +I++ EV T + + VMEY GGELF+++ AG+ +E A +FQQLIS V Sbjct: 60 NIIRFKEVCLTPTHLAIVMEYAAGGELFEQICTAGRFSEDEARYFFQQLISGV 112
>KAPC_YEAST (P05986) cAMP-dependent protein kinase type 3 (EC 2.7.11.11) (PKA| 3) Length = 398 Score = 75.9 bits (185), Expect = 9e-14 Identities = 44/168 (26%), Positives = 84/168 (50%) Frame = +1 Query: 127 HSDSAMMNPPECWIMTSGRLAEVS*HI*VVATRILLAVTYTLEGMENSGKIVMGRYELGR 306 H + + P E SG+L E + + I L L+ + SGK + +++ R Sbjct: 39 HEECSSNTPVEINGRNSGKLKEEA------SAGICLVKKPMLQYRDTSGKYSLSDFQILR 92 Query: 307 LLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHKSIVQLH 486 LG G+FG+VH ++ + R A+K + K T++K+ E E + +V+H I+++ Sbjct: 93 TLGTGSFGRVHLIRSNHNGRFYALKTLKKHTIVKLKQVEHTNDERRMLSIVSHPFIIRMW 152 Query: 487 EVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAVD 630 +++ VM+Y++GGELF + K+ + A Y ++ A++ Sbjct: 153 GTFQDSQQVFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALE 200
>ASK1_ARATH (P43291) Serine/threonine-protein kinase ASK1 (EC 2.7.11.1)| Length = 363 Score = 75.9 bits (185), Expect = 9e-14 Identities = 43/115 (37%), Positives = 64/115 (55%) Frame = +1 Query: 283 MGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVA 462 M +YEL + +G G FG K S VA+K +++ + E V REI R + Sbjct: 1 MDKYELVKDIGAGNFGVARLMKVKNSKELVAMKYIERGPKID----ENVAREIINHRSLR 56 Query: 463 HKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 H +I++ EV+ T + + MEY GGELF+++ AG+ +E A +FQQLIS V Sbjct: 57 HPNIIRFKEVVLTPTHLAIAMEYAAGGELFERICSAGRFSEDEARYFFQQLISGV 111
>KAPB_YEAST (P06245) cAMP-dependent protein kinase type 2 (EC 2.7.11.11) (PKA| 2) Length = 380 Score = 75.5 bits (184), Expect = 1e-13 Identities = 38/134 (28%), Positives = 73/134 (54%) Frame = +1 Query: 229 LLAVTYTLEGMENSGKIVMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLK 408 LL + + + GK + +++ R LG G+FG+VH +++ + R AIK++ K+ V+K Sbjct: 49 LLTSQLPQKSLVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKQQVVK 108 Query: 409 VGLAEQVRREITTMRLVAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEG 588 + E E ++LV H ++++ I+ VM+Y++GGELF + K+ + Sbjct: 109 MKQVEHTNDERRMLKLVEHPFLIRMWGTFQDARNIFMVMDYIEGGELFSLLRKSQRFPNP 168 Query: 589 AAHKYFQQLISAVD 630 A Y ++I A++ Sbjct: 169 VAKFYAAEVILALE 182
>KPK1_ARATH (P42818) Serine/threonine-protein kinase AtPK1/AtPK6 (EC 2.7.11.1)| Length = 465 Score = 75.5 bits (184), Expect = 1e-13 Identities = 41/128 (32%), Positives = 76/128 (59%), Gaps = 2/128 (1%) Frame = +1 Query: 250 LEG--MENSGKIVMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAE 423 LEG ++ SG + + +E+ +++GKGAFGKV+ + E++ A+K+M K+ +++ AE Sbjct: 118 LEGDLVKVSGVVGIDDFEVMKVVGKGAFGKVYQVRKKETSEIYAMKVMRKDHIMEKNHAE 177 Query: 424 QVRREITTMRLVAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKY 603 ++ E + + H IVQL T+ ++Y V++++ GG LF ++ G E A Y Sbjct: 178 YMKAERDILTKIDHPFIVQLKYSFQTKYRLYLVLDFINGGHLFFQLYHQGLFREDLARVY 237 Query: 604 FQQLISAV 627 +++SAV Sbjct: 238 TAEIVSAV 245
>SAPK4_ORYSA (Q5N942) Serine/threonine-protein kinase SAPK4 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 4) Length = 360 Score = 75.5 bits (184), Expect = 1e-13 Identities = 42/115 (36%), Positives = 64/115 (55%) Frame = +1 Query: 283 MGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVA 462 M +YE R +G G FG +N E+ VA+K +++ + E V REI R + Sbjct: 1 MEKYEAVRDIGSGNFGVARLMRNRETRELVAVKCIERGHRID----ENVYREIINHRSLR 56 Query: 463 HKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 H +I++ EV+ T + + VME+ GGELFD++ G+ +E A +FQQLI V Sbjct: 57 HPNIIRFKEVILTPTHLMIVMEFAAGGELFDRICDRGRFSEDEARYFFQQLICGV 111
>IPL1_YEAST (P38991) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) (Increase-in-ploidy protein 1) Length = 367 Score = 75.1 bits (183), Expect = 2e-13 Identities = 35/113 (30%), Positives = 64/113 (56%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHKS 471 +ELG+ LGKG FGKV+ ++ + A+K+M+KE ++K L +Q RRE+ + H + Sbjct: 104 FELGKKLGKGKFGKVYCVRHRSTGYICALKVMEKEEIIKYNLQKQFRREVEIQTSLNHPN 163 Query: 472 IVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAVD 630 + + + ++Y +MEY+ GE++ + G + A Y Q+ +A+D Sbjct: 164 LTKSYGYFHDEKRVYLLMEYLVNGEMYKLLRLHGPFNDILASDYIYQIANALD 216
>SAPK5_ORYSA (Q7XKA8) Serine/threonine-protein kinase SAPK5 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 5) Length = 370 Score = 75.1 bits (183), Expect = 2e-13 Identities = 42/115 (36%), Positives = 64/115 (55%) Frame = +1 Query: 283 MGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVA 462 M +YE R +G G FG +N E+ VA+K +++ + E V REI R + Sbjct: 1 MEKYEPVREIGAGNFGVAKLMRNKETRELVAMKFIERGNRID----ENVFREIVNHRSLR 56 Query: 463 HKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 H +I++ EV+ T + VMEY GGELF+++ +AG+ E A +FQQL+ V Sbjct: 57 HPNIIRFKEVVVTGRHLAIVMEYAAGGELFERICEAGRFHEDEARYFFQQLVCGV 111
>KCC1_YEAST (P27466) Calcium/calmodulin-dependent protein kinase I (EC| 2.7.11.17) Length = 446 Score = 75.1 bits (183), Expect = 2e-13 Identities = 42/115 (36%), Positives = 67/115 (58%), Gaps = 2/115 (1%) Frame = +1 Query: 289 RYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVL--KVGLAEQVRREITTMRLVA 462 +Y G+ LG G FG V AKN E+ VA+K++ K+ + KV L E + E+ ++ + Sbjct: 36 KYVFGKTLGAGTFGVVRQAKNTETGEDVAVKILIKKALKGNKVQL-EALYDELDILQRLH 94 Query: 463 HKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 H +IV + ++ K Y + + KGGELFD++ K GK TE A + +++SAV Sbjct: 95 HPNIVAFKDWFESKDKFYIITQLAKGGELFDRILKKGKFTEEDAVRILVEILSAV 149
>MYLK_DICDI (P25323) Myosin light chain kinase (EC 2.7.11.18) (MLCK)| Length = 295 Score = 74.3 bits (181), Expect = 3e-13 Identities = 39/112 (34%), Positives = 67/112 (59%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHKS 471 YE LG+GAF V+ +N ++ + AIK+++K + K + ++ E+ ++ V H + Sbjct: 8 YEFKEELGRGAFSIVYLGENKQTKQRYAIKVINKSELGK-DYEKNLKMEVDILKKVNHPN 66 Query: 472 IVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 I+ L E+ T K+Y VME + GGELFDK+ + G +E A ++++SAV Sbjct: 67 IIALKELFDTPEKLYLVMELVTGGELFDKIVEKGSYSEADAANLVKKIVSAV 118
>TSSK3_HUMAN (Q96PN8) Testis-specific serine/threonine-protein kinase 3 (EC| 2.7.11.1) (TSSK-3) (Testis-specific kinase 3) (TSK-3) (Serine/threonine-protein kinase 22C) Length = 268 Score = 74.3 bits (181), Expect = 3e-13 Identities = 40/113 (35%), Positives = 69/113 (61%), Gaps = 1/113 (0%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHKS 471 Y+LG+ +G+G + KV A + + R VAIK++DK + + + RE+ +R + HK+ Sbjct: 10 YQLGKTIGEGTYSKVKEAFSKKHQRKVAIKVIDKMGGPEEFIQRFLPRELQIVRTLDHKN 69 Query: 472 IVQLHEVMATRS-KIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 I+Q++E++ + KI VME +GG++FD V G L E A F+Q++ A+ Sbjct: 70 IIQVYEMLESADGKICLVMELAEGGDVFDCVLNGGPLPESRAKALFRQMVEAI 122
>SAPK8_ORYSA (Q7Y0B9) Serine/threonine-protein kinase SAPK8 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 8) Length = 371 Score = 73.9 bits (180), Expect = 4e-13 Identities = 41/113 (36%), Positives = 65/113 (57%) Frame = +1 Query: 289 RYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHK 468 RYEL R +G G FG ++ + VA+K +++ + + V+REI R + H Sbjct: 32 RYELVRDIGSGNFGVARLMRDRRTMELVAVKYIERGEKID----DNVQREIINHRSLKHP 87 Query: 469 SIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 +I++ EV+ T + + VMEY GGELF+++ K + +E A +FQQLIS V Sbjct: 88 NIIRFKEVILTPTHLAIVMEYASGGELFERICKNVRFSEDEARYFFQQLISGV 140
>AURKB_HUMAN (Q96GD4) Serine/threonine-protein kinase 12 (EC 2.7.11.1) (Aurora-| and Ipl1-like midbody-associated protein 1) (AIM-1) (Aurora/IPL1-related kinase 2) (Aurora-related kinase 2) (STK-1) (Aurora-B) Length = 344 Score = 73.9 bits (180), Expect = 4e-13 Identities = 38/112 (33%), Positives = 65/112 (58%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHKS 471 +E+GR LGKG FG V+ A+ +S+ VA+K++ K + K G+ Q+RREI + H + Sbjct: 77 FEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLHHPN 136 Query: 472 IVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 I++L+ R +IY ++EY GEL+ ++ K+ E ++L A+ Sbjct: 137 ILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADAL 188
>KPSH1_PINFU (Q4KTY1) Serine/threonine-protein kinase H1 homolog (EC 2.7.11.1)| Length = 415 Score = 73.6 bits (179), Expect = 5e-13 Identities = 41/116 (35%), Positives = 62/116 (53%) Frame = +1 Query: 280 VMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLV 459 V +Y++ L+G+G F KV ++ + + AIKM+D+ V E E+ +R V Sbjct: 76 VTAKYDIKALIGRGNFSKVVRVEHRVTKQPYAIKMIDR-----VQGKEVFESEVAVLRRV 130 Query: 460 AHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 H I+QL EV T+ K+Y VME GGELFD++ G TE A + ++ V Sbjct: 131 KHSYIIQLIEVFETKDKVYMVMELATGGELFDRIIAKGSFTERDATRVLNMVLDGV 186
>KPSH1_MOUSE (Q91YA2) Serine/threonine-protein kinase H1 (EC 2.7.11.1) (PSK-H1)| Length = 423 Score = 73.6 bits (179), Expect = 5e-13 Identities = 41/116 (35%), Positives = 66/116 (56%) Frame = +1 Query: 280 VMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLV 459 V +Y++ L+G+G+F +V ++ + + AIKM+ ET + G E E+ +R V Sbjct: 93 VTAKYDIKALIGRGSFSRVVRVEHRATRQPYAIKMI--ETKYREG-REVCESELRVLRRV 149 Query: 460 AHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 H +I+QL EV T+ ++Y VME GGELFD++ G TE A + Q ++ V Sbjct: 150 RHANIIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMVLDGV 205
>KPSH1_HUMAN (P11801) Serine/threonine-protein kinase H1 (EC 2.7.11.1) (PSK-H1)| Length = 423 Score = 73.6 bits (179), Expect = 5e-13 Identities = 41/116 (35%), Positives = 66/116 (56%) Frame = +1 Query: 280 VMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLV 459 V +Y++ L+G+G+F +V ++ + + AIKM+ ET + G E E+ +R V Sbjct: 93 VTAKYDIKALIGRGSFSRVVRVEHRATRQPYAIKMI--ETKYREG-REVCESELRVLRRV 149 Query: 460 AHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 H +I+QL EV T+ ++Y VME GGELFD++ G TE A + Q ++ V Sbjct: 150 RHANIIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMVLDGV 205
>IPL1_CANGA (Q6FV07) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 358 Score = 73.6 bits (179), Expect = 5e-13 Identities = 37/127 (29%), Positives = 70/127 (55%) Frame = +1 Query: 247 TLEGMENSGKIVMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQ 426 +LE + K+ + +E+GR LGKG FGKV+ ++ +S A+K ++K +L+ L +Q Sbjct: 85 SLEKSTYNNKLSLKDFEVGRKLGKGKFGKVYCVRHKKSGFICALKAIEKNEILQFNLLKQ 144 Query: 427 VRREITTMRLVAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYF 606 ++RE+ + H +I++L+ ++Y +ME+ GEL+ + G + A Y Sbjct: 145 LKREVDIQLGMDHPNIIKLYAHFHDEKRVYLLMEHSINGELYKSLKNNGPFNDVLASHYI 204 Query: 607 QQLISAV 627 Q+ A+ Sbjct: 205 YQIADAL 211
>KPSH1_BRARE (Q501V0) Serine/threonine-protein kinase H1 homolog (EC 2.7.11.1)| Length = 422 Score = 73.2 bits (178), Expect = 6e-13 Identities = 41/116 (35%), Positives = 65/116 (56%) Frame = +1 Query: 280 VMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLV 459 V +Y++ L+G+G+F +V ++ + + AIKM+ ET + G E E+ +R V Sbjct: 92 VTAKYDIKALIGRGSFSRVVRVEHRSTRQPYAIKMI--ETRYREG-REVCESELCVLRRV 148 Query: 460 AHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 H +I+QL EV T ++Y VME GGELFD++ G TE A + Q ++ V Sbjct: 149 RHTNIIQLMEVFETAERVYMVMELATGGELFDRIITRGSFTERDATRVLQMVLDGV 204
>CHK1_XENLA (Q6DE87) Serine/threonine-protein kinase Chk1 (EC 2.7.11.1) (xChk1| protein) Length = 474 Score = 73.2 bits (178), Expect = 6e-13 Identities = 38/113 (33%), Positives = 67/113 (59%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHKS 471 ++L + LG+GA+G+V A N ++ VA+K++D E +++EI R+++H + Sbjct: 9 WDLVQTLGEGAYGEVQLAVNRKTEEAVAVKIVDMTRA--ADCPENIKKEICINRMLSHTN 66 Query: 472 IVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAVD 630 IV+ + + Y +EY +GGELFD++ + E A K+FQQLI+ V+ Sbjct: 67 IVRFYGHRREGNIQYLFLEYCRGGELFDRIEPDVGMPEQDAQKFFQQLIAGVE 119
>KRAC_DICDI (P54644) RAC-family serine/threonine-protein kinase homolog (EC| 2.7.11.1) Length = 444 Score = 72.8 bits (177), Expect = 8e-13 Identities = 36/123 (29%), Positives = 68/123 (55%) Frame = +1 Query: 262 ENSGKIVMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREI 441 + S K+ + +EL L+GKG+FGKV + ++ A+K++ K+ +++ E E Sbjct: 110 KKSEKVGVADFELLNLVGKGSFGKVIQVRKKDTGEVYAMKVLSKKHIVEHNEVEHTLSER 169 Query: 442 TTMRLVAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLIS 621 ++ + H +V L+ T K+YF+++Y+ GGELF + K K TE Y +++ Sbjct: 170 NILQKINHPFLVNLNYSFQTEDKLYFILDYVNGGELFYHLQKDKKFTEDRVRYYGAEIVL 229 Query: 622 AVD 630 A++ Sbjct: 230 ALE 232
>IPL1_YARLI (Q6C3J2) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 371 Score = 72.4 bits (176), Expect = 1e-12 Identities = 35/126 (27%), Positives = 69/126 (54%) Frame = +1 Query: 250 LEGMENSGKIVMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQV 429 L G+ + +E+G+ LGKG FGKV+ K+ ++ A+K M+K+ +++ + +Q Sbjct: 85 LTGITGFRNYSLDDFEIGKALGKGKFGKVYLVKDKKTGFVSALKCMEKKELVEGNVEKQF 144 Query: 430 RREITTMRLVAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQ 609 RRE+ + H ++++L + ++Y ++EY+ GEL+ + + TE A Y Sbjct: 145 RREVEIQSNLRHTNVLRLFGHFHDKDRVYLILEYVVHGELYKLLRNQKRFTESTASSYIY 204 Query: 610 QLISAV 627 Q+ A+ Sbjct: 205 QMSEAL 210
>KPK19_ARATH (Q39030) Serine/threonine-protein kinase AtPK19 (EC 2.7.11.1)| (Ribosomal-protein S6 kinase homolog) Length = 471 Score = 72.4 bits (176), Expect = 1e-12 Identities = 37/122 (30%), Positives = 72/122 (59%) Frame = +1 Query: 262 ENSGKIVMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREI 441 E SG + + +E+ +++G+GAFGKV+ + +++ A+K+M K+ +++ AE ++ E Sbjct: 130 EVSGVVGIEDFEVLKVVGQGAFGKVYQVRKKDTSEIYAMKVMRKDKIVEKNHAEYMKAER 189 Query: 442 TTMRLVAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLIS 621 + + H IVQL T+ ++Y V++++ GG LF ++ G E A Y +++S Sbjct: 190 DILTKIDHPFIVQLKYSFQTKYRLYLVLDFINGGHLFFQLYHQGLFREDLARVYTAEIVS 249 Query: 622 AV 627 AV Sbjct: 250 AV 251
>GIN4_YEAST (Q12263) Serine/threonine-protein kinase GIN4 (EC 2.7.11.1)| Length = 1142 Score = 72.0 bits (175), Expect = 1e-12 Identities = 42/130 (32%), Positives = 72/130 (55%), Gaps = 15/130 (11%) Frame = +1 Query: 283 MGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVG---------------L 417 +G ++LG LG G+ GKV A+N + + A+K++ K V G L Sbjct: 16 IGPWKLGETLGLGSTGKVQLARNGSTGQEAAVKVISK-AVFNTGNVSGTSIVGSTTPDAL 74 Query: 418 AEQVRREITTMRLVAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAH 597 + REI M+L+ H ++++L++V T + +Y V+EY + GELF+ + + G L E A Sbjct: 75 PYGIEREIIIMKLLNHPNVLRLYDVWETNTDLYLVLEYAEKGELFNLLVERGPLPEHEAI 134 Query: 598 KYFQQLISAV 627 ++F+Q+I V Sbjct: 135 RFFRQIIIGV 144
>KPSH2_HUMAN (Q96QS6) Serine/threonine-protein kinase H2 (EC 2.7.11.1) (PSK-H2)| Length = 385 Score = 71.2 bits (173), Expect = 2e-12 Identities = 41/116 (35%), Positives = 65/116 (56%) Frame = +1 Query: 280 VMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLV 459 V+ RY++ L+G G+F +V + + + AIK+M ET + G E E++ +R V Sbjct: 59 VLARYDIKALIGTGSFSRVVRVEQKTTKKPFAIKVM--ETREREG-REACVSELSVLRRV 115 Query: 460 AHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 +H+ IVQL E+ T ++Y VME GGELFD++ G TE A + Q + + Sbjct: 116 SHRYIVQLMEIFETEDQVYMVMELATGGELFDRLIAQGSFTERDAVRILQMVADGI 171
>KCC2_YEAST (P22517) Calcium/calmodulin-dependent protein kinase II (EC| 2.7.11.17) Length = 447 Score = 71.2 bits (173), Expect = 2e-12 Identities = 39/114 (34%), Positives = 65/114 (57%), Gaps = 1/114 (0%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVR-REITTMRLVAHK 468 Y GR LG G+FG V A+ L +N VAIK++ K+ + + Q+ E++ ++ ++H Sbjct: 47 YIFGRTLGAGSFGVVRQARKLSTNEDVAIKILLKKALQGNNVQLQMLYEELSILQKLSHP 106 Query: 469 SIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAVD 630 +IV + ++ K Y V + GGELFD++ GK TE A + Q++ AV+ Sbjct: 107 NIVSFKDWFESKDKFYIVTQLATGGELFDRILSRGKFTEVDAVEIIVQILGAVE 160
>TSSK4_MOUSE (Q9D411) Testis-specific serine/threonine-protein kinase 4 (EC| 2.7.11.1) (TSSK-4) (Testis-specific kinase 4) (TSK-4) Length = 328 Score = 71.2 bits (173), Expect = 2e-12 Identities = 31/108 (28%), Positives = 66/108 (61%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHKS 471 YE+G+++G G++G V+ A + VA+K++ K+ + L + + REI M+++ HK Sbjct: 25 YEVGKIIGHGSYGTVYEAYYTKQKVMVAVKIISKKKASEDYLNKFLPREIQVMKVLRHKY 84 Query: 472 IVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQL 615 ++ ++ + T S++Y ++E +GG++ + + + G E A K+F Q+ Sbjct: 85 LINFYQAIETTSRVYIILELAQGGDVLEWIQRYGACAETLAGKWFSQM 132
>KIN4_YEAST (Q01919) Serine/threonine-protein kinase KIN4 (EC 2.7.11.1)| Length = 800 Score = 70.9 bits (172), Expect = 3e-12 Identities = 43/121 (35%), Positives = 70/121 (57%), Gaps = 6/121 (4%) Frame = +1 Query: 286 GRYELGRLLGKGAFGKVH--YAKNLESN---RGVAIKMMDKETVLKVGLAE-QVRREITT 447 G Y +G LG+G FGKV + K SN + VAIK++ ++T+ K E ++ REI Sbjct: 44 GPYIIGSTLGEGEFGKVKLGWTKASSSNEVPKQVAIKLIRRDTIKKDADKEIKIYREINA 103 Query: 448 MRLVAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 ++ + H +I+ L EV+ I V+E++ GGE + + + +L E +A + F QLIS V Sbjct: 104 LKHLTHPNIIYLEEVLQNSKYIGIVLEFVSGGEFYKYIQRKRRLKESSACRLFAQLISGV 163 Query: 628 D 630 + Sbjct: 164 N 164
>STK6_RAT (P59241) Serine/threonine-protein kinase 6 (EC 2.7.11.1) (Aurora-A)| (ratAurA) Length = 397 Score = 70.5 bits (171), Expect = 4e-12 Identities = 54/213 (25%), Positives = 97/213 (45%), Gaps = 5/213 (2%) Frame = +1 Query: 4 AERCACIEEISSVRPRTSPPCEGPFGHLLM*ATTLPASTPPHSDSAMMNPPEC---WIMT 174 A+R C V P+ P G L LPA++ P S + NP + Sbjct: 43 AQRVLCPSNSQRVPPQAQKPVAGQKPVLKQ----LPAASGPRPASRLSNPQKSEQPQPAA 98 Query: 175 SGRLAEVS*HI*VVATRILLAVTYTLEGMENSGKI--VMGRYELGRLLGKGAFGKVHYAK 348 SG +E +++ E+S K + +++GR LGKG FG V+ A+ Sbjct: 99 SGNNSEKE--------------QTSIQKTEDSKKRQWTLEDFDIGRPLGKGKFGNVYLAR 144 Query: 349 NLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHKSIVQLHEVMATRSKIYFVME 528 +S +A+K++ K + K G+ Q+RRE+ + H +I++L+ +++Y ++E Sbjct: 145 EKQSKFILALKVLFKVQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILE 204 Query: 529 YMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 Y G ++ ++ K K E Y +L +A+ Sbjct: 205 YAPLGTVYRELQKLSKFDEQRTATYITELANAL 237
>CDS1_SCHPO (Q09170) Serine/threonine-protein kinase cds1 (EC 2.7.11.1)| (Checkpoint kinase cds1) Length = 460 Score = 70.5 bits (171), Expect = 4e-12 Identities = 39/134 (29%), Positives = 67/134 (50%), Gaps = 4/134 (2%) Frame = +1 Query: 238 VTYTLEGMENSGKIVMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVG- 414 V ++ + +N K YE+ R LG G F V A + S + AIK+++K +L Sbjct: 149 VKHSRDSQKNMIKSENSHYEIIRTLGSGTFAVVKLAVEVNSGKWYAIKIINKRKILLTSS 208 Query: 415 ---LAEQVRREITTMRLVAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTE 585 E +REI ++ + H +VQ HE+ +++ VMEY++GG+L D + G + E Sbjct: 209 EKRATEMFQREIDILKSLHHPGVVQCHEIFENDDELFIVMEYVEGGDLMDFLIANGSIDE 268 Query: 586 GAAHKYFQQLISAV 627 +QL+ + Sbjct: 269 QDCKPLLKQLLETL 282
>KPCL_HUMAN (P24723) Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta)| (PKC-L) Length = 682 Score = 70.1 bits (170), Expect = 5e-12 Identities = 40/128 (31%), Positives = 73/128 (57%), Gaps = 4/128 (3%) Frame = +1 Query: 256 GMENSGKIVMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRR 435 G+ +S ++ + +E R+LGKG+FGKV A+ E+ A+K++ K+ +L L + V Sbjct: 342 GVNSSNRLGIDNFEFIRVLGKGSFGKVMLARVKETGDLYAVKVLKKDVIL---LDDDVEC 398 Query: 436 EITTMRLVA----HKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKY 603 +T R+++ H + QL T +++FVME++ GG+L + K+ + E A Y Sbjct: 399 TMTEKRILSLARNHPFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFY 458 Query: 604 FQQLISAV 627 ++ISA+ Sbjct: 459 AAEIISAL 466
>STK6_HUMAN (O14965) Serine/threonine-protein kinase 6 (EC 2.7.11.1)| (Serine/threonine kinase 15) (Aurora/IPL1-related kinase 1) (Aurora-related kinase 1) (hARK1) (Aurora-A) (Breast-tumor-amplified kinase) Length = 403 Score = 70.1 bits (170), Expect = 5e-12 Identities = 34/112 (30%), Positives = 64/112 (57%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHKS 471 +E+GR LGKG FG V+ A+ +S +A+K++ K + K G+ Q+RRE+ + H + Sbjct: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN 192 Query: 472 IVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 I++L+ +++Y ++EY G ++ ++ K K E Y +L +A+ Sbjct: 193 ILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANAL 244
>PDPK1_HUMAN (O15530) 3-phosphoinositide-dependent protein kinase 1 (EC| 2.7.11.1) (hPDK1) Length = 556 Score = 69.7 bits (169), Expect = 7e-12 Identities = 35/113 (30%), Positives = 60/113 (53%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHKS 471 ++ G++LG+G+F V A+ L ++R AIK+++K ++K V RE M + H Sbjct: 82 FKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPF 141 Query: 472 IVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAVD 630 V+L+ K+YF + Y K GEL + K G E Y +++SA++ Sbjct: 142 FVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALE 194
>PDPK1_RAT (O55173) 3-phosphoinositide-dependent protein kinase 1 (EC| 2.7.11.1) (Protein kinase B kinase) (PkB kinase) Length = 559 Score = 69.7 bits (169), Expect = 7e-12 Identities = 35/113 (30%), Positives = 60/113 (53%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHKS 471 ++ G++LG+G+F V A+ L ++R AIK+++K ++K V RE M + H Sbjct: 85 FKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPF 144 Query: 472 IVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAVD 630 V+L+ K+YF + Y K GEL + K G E Y +++SA++ Sbjct: 145 FVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALE 197
>PDPK1_MOUSE (Q9Z2A0) 3-phosphoinositide-dependent protein kinase 1 (EC| 2.7.11.1) (mPDK1) Length = 559 Score = 69.7 bits (169), Expect = 7e-12 Identities = 35/113 (30%), Positives = 60/113 (53%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHKS 471 ++ G++LG+G+F V A+ L ++R AIK+++K ++K V RE M + H Sbjct: 85 FKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPF 144 Query: 472 IVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAVD 630 V+L+ K+YF + Y K GEL + K G E Y +++SA++ Sbjct: 145 FVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALE 197
>KAPCA_BOVIN (P00517) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 69.7 bits (169), Expect = 7e-12 Identities = 35/112 (31%), Positives = 63/112 (56%) Frame = +1 Query: 283 MGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVA 462 + ++E + LG G+FG+V K++E+ A+K++DK+ V+K+ E E ++ V Sbjct: 40 LDQFERIKTLGTGSFGRVMLVKHMETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVN 99 Query: 463 HKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLI 618 +V+L S +Y VMEY+ GGE+F + + G+ +E A Y Q++ Sbjct: 100 FPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIV 151
>KCC1B_RAT (O70150) Calcium/calmodulin-dependent protein kinase type 1B (EC| 2.7.11.17) (CaM kinase IB) (CaM kinase I beta) (CaMKI-beta) (CaM-KI beta) (Pregnancy up-regulated non-ubiquitously expressed CaM kinase homolog) Length = 343 Score = 69.7 bits (169), Expect = 7e-12 Identities = 41/112 (36%), Positives = 61/112 (54%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHKS 471 YE+ LG GAF +V A+ S VA+K + K+ + G V EI +R ++H + Sbjct: 15 YEIREKLGSGAFSEVMLAQERGSAHLVALKCIPKKALR--GKEALVENEIAVLRRISHPN 72 Query: 472 IVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 IV L +V + S +Y ME + GGELFD++ + G TE A Q++ AV Sbjct: 73 IVALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAV 124
>KCC1B_MOUSE (Q9QYK9) Calcium/calmodulin-dependent protein kinase type 1B (EC| 2.7.11.17) (CaM kinase IB) (CaM kinase I beta) (CaMKI-beta) (CaM-KI beta) (Pregnancy up-regulated non-ubiquitously expressed CaM kinase homolog) Length = 343 Score = 69.7 bits (169), Expect = 7e-12 Identities = 41/112 (36%), Positives = 61/112 (54%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHKS 471 YE+ LG GAF +V A+ S VA+K + K+ + G V EI +R ++H + Sbjct: 15 YEIREKLGSGAFSEVMLAQERGSAHLVALKCIPKKALR--GKEALVENEIAVLRRISHPN 72 Query: 472 IVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 IV L +V + S +Y ME + GGELFD++ + G TE A Q++ AV Sbjct: 73 IVALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAV 124
>CHK1_CHICK (Q8AYC9) Serine/threonine-protein kinase Chk1 (EC 2.7.11.1)| Length = 476 Score = 69.7 bits (169), Expect = 7e-12 Identities = 35/112 (31%), Positives = 65/112 (58%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHKS 471 ++L + LG+GA+G+V A N + VA+K++D + E +++EI +++ H++ Sbjct: 9 WDLVQTLGEGAYGEVQLAVNRRTEEAVAVKIVDMKRA--ADCPENIKKEICINKMLNHEN 66 Query: 472 IVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 +V+ + + Y +EY GGELFD++ + E A ++FQQLI+ V Sbjct: 67 VVKFYGHRREGATQYLFLEYCSGGELFDRIEPDIGMPEPEAQRFFQQLIAGV 118
>KCC4_YEAST (P25389) Probable serine/threonine-protein kinase KCC4 (EC| 2.7.11.1) Length = 1037 Score = 69.7 bits (169), Expect = 7e-12 Identities = 38/123 (30%), Positives = 67/123 (54%), Gaps = 8/123 (6%) Frame = +1 Query: 283 MGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVG--------LAEQVRRE 438 +G ++LG LG G+ GKV A++ + A+K++ K G L + RE Sbjct: 18 IGPWKLGETLGFGSTGKVQLAQHERTGHRTAVKVISKSIFNNNGNHSNDDSVLPYNIERE 77 Query: 439 ITTMRLVAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLI 618 I M+L++H +++ L++V T + +Y ++EY + GELF+ + G L E A F+Q+I Sbjct: 78 IVIMKLLSHPNVLSLYDVWETNNNLYLILEYAEKGELFNLLVDHGPLPEREAINCFRQII 137 Query: 619 SAV 627 + Sbjct: 138 IGI 140
>KAPA_YEAST (P06244) cAMP-dependent protein kinase type 1 (EC 2.7.11.11) (PKA| 1) (CDC25-suppressing protein kinase) (PK-25) Length = 397 Score = 69.7 bits (169), Expect = 7e-12 Identities = 34/121 (28%), Positives = 67/121 (55%) Frame = +1 Query: 268 SGKIVMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITT 447 SGK + +++ R LG G+FG+VH ++ + R A+K++ KE V+++ E E Sbjct: 79 SGKYSLQDFQILRTLGTGSFGRVHLIRSRHNGRYYAMKVLKKEIVVRLKQVEHTNDERLM 138 Query: 448 MRLVAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 + +V H I+++ +I+ +M+Y++GGELF + K+ + A Y ++ A+ Sbjct: 139 LSIVTHPFIIRMWGTFQDAQQIFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLAL 198 Query: 628 D 630 + Sbjct: 199 E 199
>AKT1_XENLA (Q98TY9) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (Protein kinase Akt-1) (Protein kinase B, alpha) (PKB alpha) (xAkt) Length = 481 Score = 69.3 bits (168), Expect = 9e-12 Identities = 39/119 (32%), Positives = 60/119 (50%) Frame = +1 Query: 274 KIVMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMR 453 K+ M +E +LLGKG FGKV K + R A+K++ KE ++ E ++ Sbjct: 145 KVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQ 204 Query: 454 LVAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAVD 630 H + L T ++ FVMEY GGELF +S+ +E A Y +++SA+D Sbjct: 205 NSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERIFSEDRARFYGAEIVSALD 263
>KS6AA_CHICK (P18652) Ribosomal protein S6 kinase 2 alpha (EC 2.7.11.1)| (Ribosomal protein S6 kinase II alpha) (S6KII-alpha) (P90-RSK) (MAP kinase-activated protein kinase 1) (MAPK-activated protein kinase 1) (MAPKAP kinase 1) (MAPKAPK-1) Length = 752 Score = 69.3 bits (168), Expect = 9e-12 Identities = 42/138 (30%), Positives = 74/138 (53%), Gaps = 3/138 (2%) Frame = +1 Query: 226 ILLAVTYTLEGMENSGKIVMGRYELGRLLGKGAFGKVHYAKNL---ESNRGVAIKMMDKE 396 ++ + T E S K ++EL ++LG+G+FGKV + + +SN A+K++ K Sbjct: 58 VVKEINITHHVKEGSEKADPSQFELLKVLGQGSFGKVFLVRKITPPDSNHLYAMKVLKKA 117 Query: 397 TVLKVGLAEQVRREITTMRLVAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGK 576 T LKV + + E + V H +V+LH T K+Y ++++++GG+LF ++SK Sbjct: 118 T-LKVRDRVRTKIERDILADVNHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVM 176 Query: 577 LTEGAAHKYFQQLISAVD 630 TE Y +L +D Sbjct: 177 FTEEDVKFYLAELALGLD 194 Score = 41.6 bits (96), Expect = 0.002 Identities = 28/113 (24%), Positives = 51/113 (45%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHKS 471 Y + +G G++ + +N A+K++DK K +E++ +R H + Sbjct: 435 YVVKEAIGVGSYSVCKRCIHKTTNMEYAVKVIDKS---KRDPSEEIE---ILLRYGQHPN 488 Query: 472 IVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAVD 630 I+ L +V +Y V E M+GGEL DK+ + +E A + V+ Sbjct: 489 IITLKDVYDDGKYVYLVTELMRGGELLDKILRQKFFSEREASSVLHTICKTVE 541
>KCC1B_HUMAN (Q6P2M8) Calcium/calmodulin-dependent protein kinase type 1B (EC| 2.7.11.17) (CaM kinase IB) (CaM kinase I beta) (CaMKI-beta) (CaM-KI beta) (Pregnancy up-regulated non-ubiquitously expressed CaM kinase) Length = 343 Score = 69.3 bits (168), Expect = 9e-12 Identities = 41/112 (36%), Positives = 61/112 (54%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHKS 471 YE+ LG GAF +V A+ S VA+K + K+ + G V EI +R ++H + Sbjct: 15 YEIRERLGSGAFSEVVLAQERGSAHLVALKCIPKKALR--GKEALVENEIAVLRRISHPN 72 Query: 472 IVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 IV L +V + S +Y ME + GGELFD++ + G TE A Q++ AV Sbjct: 73 IVALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAV 124
>KPCL_RAT (Q64617) Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta)| (PKC-L) Length = 683 Score = 68.9 bits (167), Expect = 1e-11 Identities = 39/128 (30%), Positives = 72/128 (56%), Gaps = 4/128 (3%) Frame = +1 Query: 256 GMENSGKIVMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRR 435 G+ +S + + +E R+LGKG+FGKV A+ E+ A+K++ K+ +L+ + V Sbjct: 343 GVNSSSRFGIDNFEFIRVLGKGSFGKVMLARIKETGELYAVKVLKKDVILQ---DDDVEC 399 Query: 436 EITTMRLVA----HKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKY 603 +T R+++ H + QL T +++FVME++ GG+L + K+ + E A Y Sbjct: 400 TMTEKRILSLARNHPFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFY 459 Query: 604 FQQLISAV 627 ++ISA+ Sbjct: 460 AAEIISAL 467
>KPCL_MOUSE (P23298) Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta)| (PKC-L) Length = 683 Score = 68.9 bits (167), Expect = 1e-11 Identities = 39/128 (30%), Positives = 72/128 (56%), Gaps = 4/128 (3%) Frame = +1 Query: 256 GMENSGKIVMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRR 435 G+ +S + + +E R+LGKG+FGKV A+ E+ A+K++ K+ +L+ + V Sbjct: 343 GVNSSSRFGIDNFEFIRVLGKGSFGKVMLARIKETGELYAVKVLKKDVILQ---DDDVEC 399 Query: 436 EITTMRLVA----HKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKY 603 +T R+++ H + QL T +++FVME++ GG+L + K+ + E A Y Sbjct: 400 TMTEKRILSLARNHPFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFY 459 Query: 604 FQQLISAV 627 ++ISA+ Sbjct: 460 AAEIISAL 467
>AAIP_WHEAT (Q02066) Abscisic acid-inducible protein kinase (EC 2.7.11.1)| (Fragment) Length = 332 Score = 68.9 bits (167), Expect = 1e-11 Identities = 36/105 (34%), Positives = 58/105 (55%) Frame = +1 Query: 313 GKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHKSIVQLHEV 492 G G FG +++ + A+K +++ + E V+REI R + H +I++ EV Sbjct: 1 GSGNFGVAKLVRDVRTKEHFAVKFIERGHKID----EHVQREIMNHRSLKHPNIIRFKEV 56 Query: 493 MATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 + T + + VMEY GGELF ++ AG+ +E +FQQLIS V Sbjct: 57 VLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFFQQLISGV 101
>KS6A_CAEEL (Q21734) Putative ribosomal protein S6 kinase alpha (EC 2.7.11.1)| Length = 784 Score = 68.6 bits (166), Expect = 1e-11 Identities = 37/117 (31%), Positives = 69/117 (58%), Gaps = 3/117 (2%) Frame = +1 Query: 289 RYELGRLLGKGAFGKVHYAKNL---ESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLV 459 ++EL ++LG+G+FGKV + + +S A+K++ K T LKV ++ + E + + Sbjct: 103 QFELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVLKKAT-LKVRDRQRTKLERNILAHI 161 Query: 460 AHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAVD 630 +H IV+LH T K+Y ++++++GG+LF ++SK TE Y +L A++ Sbjct: 162 SHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEDDVKFYLAELTLALE 218 Score = 43.1 bits (100), Expect = 7e-04 Identities = 31/113 (27%), Positives = 52/113 (46%), Gaps = 1/113 (0%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHKS 471 YE+ +G GA VH + + R A+K ++K + + +R H+ Sbjct: 454 YEILEKIGNGAHSVVHKCQMKATRRKYAVK------IVKKAVFDATEEVDILLRHSHHQF 507 Query: 472 IVQLHEVMATRSKIYFVMEYMKGGELFDK-VSKAGKLTEGAAHKYFQQLISAV 627 +V+L +V + IY + E +GGEL DK V+K +E L++AV Sbjct: 508 VVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAAIMANLLNAV 560
>AKT1_RAT (P47196) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (Protein kinase B) (PKB) Length = 480 Score = 68.6 bits (166), Expect = 1e-11 Identities = 38/119 (31%), Positives = 60/119 (50%) Frame = +1 Query: 274 KIVMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMR 453 ++ M +E +LLGKG FGKV K + R A+K++ KE ++ E ++ Sbjct: 144 RVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQ 203 Query: 454 LVAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAVD 630 H + L T ++ FVMEY GGELF +S+ +E A Y +++SA+D Sbjct: 204 NSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALD 262
>AKT1_MOUSE (P31750) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (AKT1 kinase) (Protein kinase B) (PKB) (C-AKT) (Thymoma viral proto-oncogene) Length = 480 Score = 68.6 bits (166), Expect = 1e-11 Identities = 38/119 (31%), Positives = 60/119 (50%) Frame = +1 Query: 274 KIVMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMR 453 ++ M +E +LLGKG FGKV K + R A+K++ KE ++ E ++ Sbjct: 144 RVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQ 203 Query: 454 LVAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAVD 630 H + L T ++ FVMEY GGELF +S+ +E A Y +++SA+D Sbjct: 204 NSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALD 262
>AKT1_HUMAN (P31749) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (Protein kinase B) (PKB) (C-AKT) Length = 480 Score = 68.6 bits (166), Expect = 1e-11 Identities = 38/119 (31%), Positives = 60/119 (50%) Frame = +1 Query: 274 KIVMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMR 453 ++ M +E +LLGKG FGKV K + R A+K++ KE ++ E ++ Sbjct: 144 RVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQ 203 Query: 454 LVAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAVD 630 H + L T ++ FVMEY GGELF +S+ +E A Y +++SA+D Sbjct: 204 NSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALD 262
>AKT_MLVAT (P31748) AKT kinase transforming protein (EC 2.7.11.1)| Length = 501 Score = 68.6 bits (166), Expect = 1e-11 Identities = 38/119 (31%), Positives = 60/119 (50%) Frame = +1 Query: 274 KIVMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMR 453 ++ M +E +LLGKG FGKV K + R A+K++ KE ++ E ++ Sbjct: 165 RVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQ 224 Query: 454 LVAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAVD 630 H + L T ++ FVMEY GGELF +S+ +E A Y +++SA+D Sbjct: 225 NSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALD 283
>KS6A3_MOUSE (P18654) Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1)| (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (MAP kinase-activated protein kinase 1b) (MAPKAPK1B) Length = 740 Score = 68.6 bits (166), Expect = 1e-11 Identities = 43/136 (31%), Positives = 77/136 (56%), Gaps = 3/136 (2%) Frame = +1 Query: 232 LAVTYTLEGMENSGKIVMGRYELGRLLGKGAFGKVHYAKNL---ESNRGVAIKMMDKETV 402 +A+T+ ++ E K ++EL ++LG+G+FGKV K + ++ + A+K++ K T Sbjct: 50 IAITHHVK--EGHEKADPSQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKAT- 106 Query: 403 LKVGLAEQVRREITTMRLVAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLT 582 LKV + + E + V H IV+LH T K+Y ++++++GG+LF ++SK T Sbjct: 107 LKVRDRVRTKMERDILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFT 166 Query: 583 EGAAHKYFQQLISAVD 630 E Y +L A+D Sbjct: 167 EEDVKFYLAELALALD 182 Score = 42.0 bits (97), Expect = 0.001 Identities = 29/101 (28%), Positives = 48/101 (47%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHKS 471 YE+ +G G++ + +N A+K++DK K E++ +R H + Sbjct: 422 YEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKS---KRDPTEEIE---ILLRYGQHPN 475 Query: 472 IVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAA 594 I+ L +V +Y V E MKGGEL DK+ + +E A Sbjct: 476 IITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREA 516
>KS6A3_HUMAN (P51812) Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1)| (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protei Length = 740 Score = 68.6 bits (166), Expect = 1e-11 Identities = 43/136 (31%), Positives = 77/136 (56%), Gaps = 3/136 (2%) Frame = +1 Query: 232 LAVTYTLEGMENSGKIVMGRYELGRLLGKGAFGKVHYAKNL---ESNRGVAIKMMDKETV 402 +A+T+ ++ E K ++EL ++LG+G+FGKV K + ++ + A+K++ K T Sbjct: 50 IAITHHVK--EGHEKADPSQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKAT- 106 Query: 403 LKVGLAEQVRREITTMRLVAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLT 582 LKV + + E + V H IV+LH T K+Y ++++++GG+LF ++SK T Sbjct: 107 LKVRDRVRTKMERDILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFT 166 Query: 583 EGAAHKYFQQLISAVD 630 E Y +L A+D Sbjct: 167 EEDVKFYLAELALALD 182 Score = 42.0 bits (97), Expect = 0.001 Identities = 29/101 (28%), Positives = 48/101 (47%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHKS 471 YE+ +G G++ + +N A+K++DK K E++ +R H + Sbjct: 422 YEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKS---KRDPTEEIE---ILLRYGQHPN 475 Query: 472 IVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAA 594 I+ L +V +Y V E MKGGEL DK+ + +E A Sbjct: 476 IITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREA 516
>KAPCA_SHEEP (Q9MZD9) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 68.6 bits (166), Expect = 1e-11 Identities = 35/112 (31%), Positives = 62/112 (55%) Frame = +1 Query: 283 MGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVA 462 + ++E + LG G+FG+V K+ E+ A+K++DK+ V+K+ E E ++ V Sbjct: 40 LDQFERIKTLGTGSFGRVMLVKHTETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVN 99 Query: 463 HKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLI 618 +V+L S +Y VMEY+ GGE+F + + G+ +E A Y Q++ Sbjct: 100 FPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIV 151
>KAPCA_PIG (P36887) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 68.6 bits (166), Expect = 1e-11 Identities = 35/112 (31%), Positives = 62/112 (55%) Frame = +1 Query: 283 MGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVA 462 + ++E + LG G+FG+V K+ E+ A+K++DK+ V+K+ E E ++ V Sbjct: 40 LDQFERIKTLGTGSFGRVMLVKHKETGNHFAMKILDKQKVVKLKQIEHTLNEKRILQAVN 99 Query: 463 HKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLI 618 +V+L S +Y VMEY+ GGE+F + + G+ +E A Y Q++ Sbjct: 100 FPFLVKLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIV 151
>STK33_HUMAN (Q9BYT3) Serine/threonine-protein kinase 33 (EC 2.7.11.1)| Length = 514 Score = 68.6 bits (166), Expect = 1e-11 Identities = 42/122 (34%), Positives = 66/122 (54%), Gaps = 2/122 (1%) Frame = +1 Query: 268 SGKIVMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLA--EQVRREI 441 +G + Y GR+LGKG+FG V A + E+ AIK ++KE K G + + + RE+ Sbjct: 108 NGAAIEEIYTFGRILGKGSFGIVIEATDKETETKWAIKKVNKE---KAGSSAVKLLEREV 164 Query: 442 TTMRLVAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLIS 621 ++ V H+ I+ L +V T K+Y VME + GEL + + + G +E Q L S Sbjct: 165 NILKSVKHEHIIHLEQVFETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLAS 224 Query: 622 AV 627 A+ Sbjct: 225 AI 226
>KAPCA_CANFA (Q8MJ44) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 349 Score = 68.2 bits (165), Expect = 2e-11 Identities = 35/112 (31%), Positives = 62/112 (55%) Frame = +1 Query: 283 MGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVA 462 + ++E + LG G+FG+V K+ E+ A+K++DK+ V+K+ E E ++ V Sbjct: 39 LDQFERIKTLGTGSFGRVMLVKHKETGNHFAMKILDKQKVVKLKQIEHTLNEKRILQAVN 98 Query: 463 HKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLI 618 +V+L S +Y VMEY+ GGE+F + + G+ +E A Y Q++ Sbjct: 99 FPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIV 150
>AKT2_MOUSE (Q60823) RAC-beta serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta) Length = 481 Score = 68.2 bits (165), Expect = 2e-11 Identities = 37/119 (31%), Positives = 60/119 (50%) Frame = +1 Query: 274 KIVMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMR 453 K+ M ++ +LLGKG FGKV + + R A+K++ KE ++ E ++ Sbjct: 146 KVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQ 205 Query: 454 LVAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAVD 630 H + L T ++ FVMEY GGELF +S+ TE A Y +++SA++ Sbjct: 206 NTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEDRARFYGAEIVSALE 264
>AKT1_BOVIN (Q01314) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (Protein kinase B) (PKB) Length = 480 Score = 68.2 bits (165), Expect = 2e-11 Identities = 38/119 (31%), Positives = 60/119 (50%) Frame = +1 Query: 274 KIVMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMR 453 ++ M +E +LLGKG FGKV K + A+K++ KE ++ E ++ Sbjct: 144 RVTMNEFEYVKLLGKGTFGKVILVKEKATAAYYAMKILKKEVIVAKDEVAHTLTENRVLQ 203 Query: 454 LVAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAVD 630 H S+ L T ++ FVMEY GGELF +S+ +E A Y +++SA+D Sbjct: 204 NSRHPSLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALD 262
>KPK2_PLAFK (Q02595) Probable serine/threonine-protein kinase 2 (EC 2.7.11.1)| Length = 510 Score = 68.2 bits (165), Expect = 2e-11 Identities = 37/113 (32%), Positives = 60/113 (53%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHKS 471 Y L + +GKG+F + N+ V +K +DK V + V EI +R V HK Sbjct: 111 YVLNKKIGKGSFSTAYIGTNILYGNRVVVKEVDKSKVKE----SNVYTEIEVLRKVMHKY 166 Query: 472 IVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAVD 630 I++L +Y V+EY+KGGELF+ ++ G TE A K ++++ A++ Sbjct: 167 IIKLISAYEQEGFVYLVLEYLKGGELFEYLNNNGPYTEQVAKKAMKRVLIALE 219
>DCAK1_HUMAN (O15075) Serine/threonine-protein kinase DCAMKL1 (EC 2.7.11.1)| (Doublecortin-like and CAM kinase-like 1) Length = 740 Score = 68.2 bits (165), Expect = 2e-11 Identities = 39/113 (34%), Positives = 60/113 (53%) Frame = +1 Query: 289 RYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHK 468 RY++GR +G G F V + R A+K++ K G ++ E++ +R V H Sbjct: 389 RYKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCR--GKEHMIQNEVSILRRVKHP 446 Query: 469 SIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 +IV L E M +++Y VME +KGG+LFD ++ K TE A L SA+ Sbjct: 447 NIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAI 499
>TSSK4_HUMAN (Q6SA08) Testis-specific serine/threonine-protein kinase 4 (EC| 2.7.11.1) (TSSK-4) (Testis-specific kinase 4) (TSK-4) (Serine/threonine-protein kinase 22E) Length = 328 Score = 68.2 bits (165), Expect = 2e-11 Identities = 31/108 (28%), Positives = 64/108 (59%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHKS 471 YE+G+ +G G++G V+ A + VA+K++ K+ L + + REI M+++ HK Sbjct: 25 YEVGKAIGHGSYGSVYEAFYTKQKVMVAVKIISKKKASDDYLNKFLPREIQVMKVLRHKY 84 Query: 472 IVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQL 615 ++ + + + S++Y ++E +GG++ + + + G +E A K+F QL Sbjct: 85 LINFYRAIESTSRVYIILELAQGGDVLEWIQRYGACSEPLAGKWFSQL 132
>KAPCG_HUMAN (P22612) cAMP-dependent protein kinase, gamma-catalytic subunit (EC| 2.7.11.11) (PKA C-gamma) Length = 350 Score = 68.2 bits (165), Expect = 2e-11 Identities = 35/113 (30%), Positives = 65/113 (57%) Frame = +1 Query: 289 RYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHK 468 ++E R LG G+FG+V ++ E+ A+K+++K+ V+K+ E + E ++ + Sbjct: 42 QFERLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAIDFP 101 Query: 469 SIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 +V+L S +Y VMEY+ GGE+F ++ + G+ +E A Y Q++ AV Sbjct: 102 FLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAV 154
>KAPCA_MOUSE (P05132) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 68.2 bits (165), Expect = 2e-11 Identities = 35/112 (31%), Positives = 62/112 (55%) Frame = +1 Query: 283 MGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVA 462 + +++ + LG G+FG+V K+ ES A+K++DK+ V+K+ E E ++ V Sbjct: 40 LDQFDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVN 99 Query: 463 HKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLI 618 +V+L S +Y VMEY+ GGE+F + + G+ +E A Y Q++ Sbjct: 100 FPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYAAQIV 151
>KAPCA_HUMAN (P17612) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 68.2 bits (165), Expect = 2e-11 Identities = 35/112 (31%), Positives = 62/112 (55%) Frame = +1 Query: 283 MGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVA 462 + ++E + LG G+FG+V K+ E+ A+K++DK+ V+K+ E E ++ V Sbjct: 40 LDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVN 99 Query: 463 HKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLI 618 +V+L S +Y VMEY+ GGE+F + + G+ +E A Y Q++ Sbjct: 100 FPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIV 151
>SCH9_YEAST (P11792) Serine/threonine-protein kinase SCH9 (EC 2.7.11.1)| Length = 823 Score = 68.2 bits (165), Expect = 2e-11 Identities = 47/143 (32%), Positives = 73/143 (51%), Gaps = 3/143 (2%) Frame = +1 Query: 211 VVATRILLAVTYTLEGMENSGKIVMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMD 390 VV+ IL+ TY + G +E+ RLLGKG FG+V+ K ++ R A+K++ Sbjct: 387 VVSGDILIKWTYKQTKKRHYGP---QDFEVLRLLGKGTFGQVYQVKKKDTQRIYAMKVLS 443 Query: 391 KETVLKVGLAEQVRREITTMRLVAHKS---IVQLHEVMATRSKIYFVMEYMKGGELFDKV 561 K+ ++K E + A KS IV L T + +Y V +YM GGELF + Sbjct: 444 KKVIVKKNEIAHTIGERNILVTTASKSSPFIVGLKFSFQTPTDLYLVTDYMSGGELFWHL 503 Query: 562 SKAGKLTEGAAHKYFQQLISAVD 630 K G+ +E A Y +L+ A++ Sbjct: 504 QKEGRFSEDRAKFYIAELVLALE 526
>AKT2A_XENLA (Q7ZX15) RAC-beta serine/threonine-protein kinase-A (EC 2.7.11.1)| (RAC-PK-beta-A) (Protein kinase Akt-2-A) (Protein kinase B, beta-A) (PKB beta-A) Length = 486 Score = 68.2 bits (165), Expect = 2e-11 Identities = 37/119 (31%), Positives = 60/119 (50%) Frame = +1 Query: 274 KIVMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMR 453 K+ M ++ +LLGKG FGKV + + R A+K++ KE ++ E ++ Sbjct: 151 KVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTLTESRVLQ 210 Query: 454 LVAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAVD 630 H + L T ++ FVMEY GGELF +S+ TE A Y +++SA++ Sbjct: 211 NTKHPFLTALKYAFQTSDRLCFVMEYANGGELFFHLSRERVFTEDRARFYGAEIVSALE 269
>CDR2_SCHPO (P87050) Mitosis inducer protein kinase cdr2 (EC 2.7.11.1)| Length = 775 Score = 67.8 bits (164), Expect = 3e-11 Identities = 34/116 (29%), Positives = 65/116 (56%) Frame = +1 Query: 283 MGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVA 462 +G +ELG LG G AK+ E+ + +K + + L ++ E+ +RL+ Sbjct: 7 VGPWELGLSLGSGGPNSSRLAKHRETGQLAVVKPIVGWSELTSSQQARIEGELVLLRLIE 66 Query: 463 HKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAVD 630 H +++QL +V++ + +++ V+EYM GGELFD + + G TE K+ Q++ ++ Sbjct: 67 HPNVLQLIDVISAQEQLFVVVEYMPGGELFDCMLRKGSFTEQDTAKFLWQILCGLE 122
>DCAK1_RAT (O08875) Serine/threonine-protein kinase DCAMKL1 (EC 2.7.11.1)| (Doublecortin-like and CAM kinase-like 1) (Calcium/calmodulin-dependent protein kinase type I-like CPG16) Length = 433 Score = 67.8 bits (164), Expect = 3e-11 Identities = 39/113 (34%), Positives = 60/113 (53%) Frame = +1 Query: 289 RYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHK 468 RY++GR +G G F V + R A+K++ K G ++ E++ +R V H Sbjct: 82 RYKVGRTIGDGNFAVVKECIERSTAREYALKIIKKSKCR--GKEHMIQNEVSILRRVKHP 139 Query: 469 SIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 +IV L E M +++Y VME +KGG+LFD ++ K TE A L SA+ Sbjct: 140 NIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTSKYTERDASGMLYNLASAI 192
>AKT2_HUMAN (P31751) RAC-beta serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta) Length = 481 Score = 67.8 bits (164), Expect = 3e-11 Identities = 37/119 (31%), Positives = 60/119 (50%) Frame = +1 Query: 274 KIVMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMR 453 K+ M ++ +LLGKG FGKV + + R A+K++ KE ++ E ++ Sbjct: 146 KVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQ 205 Query: 454 LVAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAVD 630 H + L T ++ FVMEY GGELF +S+ TE A Y +++SA++ Sbjct: 206 NTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEIVSALE 264
>CRK_DAUCA (P53681) CDPK-related protein kinase (EC 2.7.11.1) (PK421)| Length = 602 Score = 67.8 bits (164), Expect = 3e-11 Identities = 38/118 (32%), Positives = 65/118 (55%), Gaps = 5/118 (4%) Frame = +1 Query: 289 RYELGRLLGKGAFG---KVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMR-L 456 ++E+G +G+G FG + + K + VA+K++ K + E VRRE+ +R L Sbjct: 147 KFEVGEEVGRGHFGYTCRAKFKKGEFKGQDVAVKVIPKAKMTTAIAIEDVRREVKILRAL 206 Query: 457 VAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKV-SKAGKLTEGAAHKYFQQLISAV 627 H ++VQ ++ + +Y VME +GGEL D++ S+ GK TE A Q+++ V Sbjct: 207 TGHNNLVQFYDAFEDHTNVYVVMELCEGGELLDRILSRGGKYTEDDAKAVMIQILNVV 264
>DCAK1_MOUSE (Q9JLM8) Serine/threonine-protein kinase DCAMKL1 (EC 2.7.11.1)| (Doublecortin-like and CAM kinase-like 1) Length = 756 Score = 67.8 bits (164), Expect = 3e-11 Identities = 39/113 (34%), Positives = 60/113 (53%) Frame = +1 Query: 289 RYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHK 468 RY++GR +G G F V + R A+K++ K G ++ E++ +R V H Sbjct: 405 RYKVGRTIGDGNFAVVKECIERSTAREYALKIIKKSKCR--GKEHMIQNEVSILRRVKHP 462 Query: 469 SIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 +IV L E M +++Y VME +KGG+LFD ++ K TE A L SA+ Sbjct: 463 NIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTSKYTERDASGMLYNLASAI 515
>KAPCA_RAT (P27791) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 67.8 bits (164), Expect = 3e-11 Identities = 35/105 (33%), Positives = 58/105 (55%) Frame = +1 Query: 304 RLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHKSIVQL 483 + LG G+FG+V K+ ES A+K++DK+ V+K+ E E ++ V +V+L Sbjct: 47 KTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKL 106 Query: 484 HEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLI 618 S +Y VMEY+ GGE+F + + G+ +E A Y Q++ Sbjct: 107 EFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIV 151
>YP141_YEAST (Q03002) Putative serine/threonine-protein kinase YPL141C (EC| 2.7.11.1) Length = 865 Score = 67.4 bits (163), Expect = 3e-11 Identities = 44/128 (34%), Positives = 70/128 (54%), Gaps = 11/128 (8%) Frame = +1 Query: 277 IVMGRYELGRLLGKGAFGKVH--YAKNLESN--------RGVAIKMMDKETVLKVGLAE- 423 + G Y LG LG+G FGKV + KN ++ + VAIK++ ++++ E Sbjct: 36 VTFGPYILGSTLGEGEFGKVKLGWPKNFSNSSNSTFDFPKQVAIKLIKRDSISNDYRKEV 95 Query: 424 QVRREITTMRLVAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKY 603 ++ REI ++ ++H +IV+L EV+ I V+EY GGE + + K +L E A + Sbjct: 96 KIYREINALKHLSHPNIVKLEEVLQNSRYIGIVLEYACGGEFYKYIQKKRRLKEMNACRL 155 Query: 604 FQQLISAV 627 F QLIS V Sbjct: 156 FSQLISGV 163
>TSSK1_MOUSE (Q61241) Testis-specific serine/threonine-protein kinase 1 (EC| 2.7.11.1) (TSSK-1) (Testis-specific kinase 1) (TSK-1) (Serine/threonine-protein kinase 22A) Length = 364 Score = 67.4 bits (163), Expect = 3e-11 Identities = 41/124 (33%), Positives = 69/124 (55%), Gaps = 1/124 (0%) Frame = +1 Query: 259 MENSGKIVMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRRE 438 M+++ + Y +G LG+G++ KV A + VA+K++D++ L + + RE Sbjct: 1 MDDAAVLKRRGYIMGINLGEGSYAKVKSAYSERLKFNVAVKIIDRKKAPSDFLEKFLPRE 60 Query: 439 ITTMRLVAHKSIVQLHEVMATR-SKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQL 615 I + ++ H+SIV+ +E+ AT K+Y VME G+L + + G L E A K F QL Sbjct: 61 IEILAMLNHRSIVKTYEIFATSDGKVYIVMELGVQGDLLEFIKTRGALQEDDARKKFHQL 120 Query: 616 ISAV 627 SA+ Sbjct: 121 SSAI 124
>DAPK3_HUMAN (O43293) Death-associated protein kinase 3 (EC 2.7.11.1) (DAP| kinase 3) (DAP-like kinase) (Dlk) (ZIP-kinase) Length = 454 Score = 67.4 bits (163), Expect = 3e-11 Identities = 34/119 (28%), Positives = 66/119 (55%), Gaps = 3/119 (2%) Frame = +1 Query: 280 VMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVL--KVGLA-EQVRREITTM 450 V YE+G LG G F V + + + A K + K + + G++ E++ RE+ + Sbjct: 9 VEDHYEMGEELGSGQFAIVRKCRQKGTGKEYAAKFIKKRRLSSSRRGVSREEIEREVNIL 68 Query: 451 RLVAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 R + H +I+ LH++ ++ + ++E + GGELFD +++ LTE A ++ +Q++ V Sbjct: 69 REIRHPNIITLHDIFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGV 127
>PLK4_HUMAN (O00444) Serine/threonine-protein kinase PLK4 (EC 2.7.11.21)| (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase Sak) (Serine/threonine-protein kinase 18) Length = 970 Score = 67.0 bits (162), Expect = 4e-11 Identities = 34/113 (30%), Positives = 65/113 (57%), Gaps = 1/113 (0%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHKS 471 +++G LLGKG+F V+ A+++ + VAIKM+DK+ + K G+ ++V+ E+ + H S Sbjct: 12 FKVGNLLGKGSFAGVYRAESIHTGLEVAIKMIDKKAMYKAGMVQRVQNEVKIHCQLKHPS 71 Query: 472 IVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGK-LTEGAAHKYFQQLISAV 627 I++L+ + +Y V+E GE+ + K +E A + Q+I+ + Sbjct: 72 ILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITGM 124
>CDPK4_PLAYO (Q7RJG2) Calcium-dependent protein kinase 4 (EC 2.7.11.1)| Length = 527 Score = 67.0 bits (162), Expect = 4e-11 Identities = 34/123 (27%), Positives = 71/123 (57%) Frame = +1 Query: 259 MENSGKIVMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRRE 438 ++NS + +Y+ ++LGKG+FG+V +K+ + AIK++ K+ V + + + RE Sbjct: 58 IQNSNVVFNEQYKGIKILGKGSFGEVILSKDKHTGHEYAIKVISKKHVKRKTDKQSLLRE 117 Query: 439 ITTMRLVAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLI 618 + ++++ H +I++L+E + Y V + GGELFD++ + E A + +Q++ Sbjct: 118 VELLKMLDHINIMKLYEFFEDNNYYYLVSDVYSGGELFDEIISRKRFYEVDAARIIKQVL 177 Query: 619 SAV 627 S + Sbjct: 178 SGI 180
>CDPK4_PLABA (P62345) Calcium-dependent protein kinase 4 (EC 2.7.11.1) (PbCDPK4)| Length = 527 Score = 67.0 bits (162), Expect = 4e-11 Identities = 34/123 (27%), Positives = 71/123 (57%) Frame = +1 Query: 259 MENSGKIVMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRRE 438 ++NS + +Y+ ++LGKG+FG+V +K+ + AIK++ K+ V + + + RE Sbjct: 58 IQNSNVVFNEQYKGIKILGKGSFGEVILSKDKHTGHEYAIKVISKKHVKRKTDKQSLLRE 117 Query: 439 ITTMRLVAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLI 618 + ++++ H +I++L+E + Y V + GGELFD++ + E A + +Q++ Sbjct: 118 VELLKMLDHINIMKLYEFFEDNNYYYLVSDVYSGGELFDEIISRKRFYEVDAARIIKQVL 177 Query: 619 SAV 627 S + Sbjct: 178 SGI 180
>KS6A1_MOUSE (P18653) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1)| (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 724 Score = 67.0 bits (162), Expect = 4e-11 Identities = 42/138 (30%), Positives = 73/138 (52%), Gaps = 3/138 (2%) Frame = +1 Query: 226 ILLAVTYTLEGMENSGKIVMGRYELGRLLGKGAFGKVHYAKNL---ESNRGVAIKMMDKE 396 IL ++ T S K ++EL ++LG+G+FGKV + + +S A+K++ K Sbjct: 40 ILKEISITHHVKAGSEKADPSQFELLKVLGQGSFGKVFLVRKVTRPDSGHLYAMKVLKKA 99 Query: 397 TVLKVGLAEQVRREITTMRLVAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGK 576 T LKV + + E + V H +V+LH T K+Y ++++++GG+LF ++SK Sbjct: 100 T-LKVRDRVRTKMERDILADVNHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVM 158 Query: 577 LTEGAAHKYFQQLISAVD 630 TE Y +L +D Sbjct: 159 FTEEDVKFYLAELALGLD 176 Score = 40.8 bits (94), Expect = 0.003 Identities = 27/101 (26%), Positives = 48/101 (47%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHKS 471 Y + +G G++ + +N A+K++DK K +E++ +R H + Sbjct: 407 YVVKETIGVGSYSVCKRCVHKATNMEYAVKVIDKS---KRDPSEEIE---ILLRYGQHPN 460 Query: 472 IVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAA 594 I+ L +V +Y V E M+GGEL DK+ + +E A Sbjct: 461 IITLKDVYDDGKHVYLVTELMRGGELLDKILRQKFFSEREA 501
>AKT2_RAT (P47197) RAC-beta serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta) Length = 481 Score = 67.0 bits (162), Expect = 4e-11 Identities = 36/119 (30%), Positives = 60/119 (50%) Frame = +1 Query: 274 KIVMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMR 453 K+ M ++ +LLGKG FGKV + + R A+K++ KE ++ E ++ Sbjct: 146 KVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQ 205 Query: 454 LVAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAVD 630 H + L T ++ FVMEY GG+LF +S+ TE A Y +++SA++ Sbjct: 206 NTRHPFLTALKYAFQTHDRLCFVMEYANGGDLFFHLSRERVFTEDRARFYGAEIVSALE 264
>KAPCB_HUMAN (P22694) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 67.0 bits (162), Expect = 4e-11 Identities = 34/109 (31%), Positives = 60/109 (55%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHKS 471 +E + LG G+FG+V K+ + + A+K++DK+ V+K+ E E ++ V Sbjct: 43 FERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPF 102 Query: 472 IVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLI 618 +V+L S +Y VMEY+ GGE+F + + G+ +E A Y Q++ Sbjct: 103 LVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIV 151
>KAPB1_BOVIN (P05131) cAMP-dependent protein kinase, beta-1-catalytic subunit| (EC 2.7.11.11) (PKA C-beta-1) Length = 350 Score = 67.0 bits (162), Expect = 4e-11 Identities = 34/109 (31%), Positives = 60/109 (55%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHKS 471 +E + LG G+FG+V K+ + + A+K++DK+ V+K+ E E ++ V Sbjct: 43 FERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPF 102 Query: 472 IVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLI 618 +V+L S +Y VMEY+ GGE+F + + G+ +E A Y Q++ Sbjct: 103 LVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIV 151
>KAPB2_BOVIN (P24256) cAMP-dependent protein kinase, beta-2-catalytic subunit| (EC 2.7.11.11) (PKA C-beta-2) Length = 397 Score = 67.0 bits (162), Expect = 4e-11 Identities = 34/109 (31%), Positives = 60/109 (55%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHKS 471 +E + LG G+FG+V K+ + + A+K++DK+ V+K+ E E ++ V Sbjct: 90 FERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPF 149 Query: 472 IVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLI 618 +V+L S +Y VMEY+ GGE+F + + G+ +E A Y Q++ Sbjct: 150 LVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIV 198
>IPL1_DEBHA (Q6BVA0) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 412 Score = 67.0 bits (162), Expect = 4e-11 Identities = 35/121 (28%), Positives = 62/121 (51%) Frame = +1 Query: 268 SGKIVMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITT 447 S + + +E+G++LGKG GKV+ K+ S A+K+M K+ ++ + L + RREI Sbjct: 140 SRHMTLDDFEIGKVLGKGKLGKVYCVKHKTSGYIAALKVMAKKDLIDLKLEKNFRREIEI 199 Query: 448 MRLVAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 + H I +L+ +Y ++EY GEL+ + + + A Y Q+ A+ Sbjct: 200 QSNLIHPKISRLYGFFYDHKNVYLILEYSIHGELYHHLKVQRRFNDATASHYIYQVALAL 259 Query: 628 D 630 D Sbjct: 260 D 260
>STK6_MOUSE (P97477) Serine/threonine-protein kinase 6 (EC 2.7.11.1)| (Aurora-family kinase 1) (Aurora/IPL1-related kinase 1) (Ipl1- and aurora-related kinase 1) (Aurora-A) (Serine/threonine-protein kinase Ayk1) Length = 395 Score = 66.6 bits (161), Expect = 6e-11 Identities = 32/112 (28%), Positives = 63/112 (56%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHKS 471 +++GR LGKG FG V+ A+ +S +A+K++ K + K + Q+RRE+ + H + Sbjct: 124 FDIGRPLGKGKFGNVYLARERQSKFILALKVLFKTQLEKANVEHQLRREVEIQSHLRHPN 183 Query: 472 IVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 I++L+ +++Y ++EY G ++ ++ K K E Y +L +A+ Sbjct: 184 ILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANAL 235
>CDPK4_PLAF7 (Q8IBS5) Calcium-dependent protein kinase 4 (EC 2.7.11.1)| Length = 527 Score = 66.6 bits (161), Expect = 6e-11 Identities = 34/123 (27%), Positives = 71/123 (57%) Frame = +1 Query: 259 MENSGKIVMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRRE 438 ++NS + +Y+ ++LGKG+FG+V +++ + AIK++ K+ V + E + RE Sbjct: 58 IQNSNVVFNEQYKGIKILGKGSFGEVILSRDKHTGHEYAIKVISKKHVKRKTDKESLLRE 117 Query: 439 ITTMRLVAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLI 618 + ++++ H +I++L+E + Y V + GGELFD++ + E A + +Q++ Sbjct: 118 VELLKMLDHINIMKLYEFFEDNNYYYLVSDVYTGGELFDEIISRKRFYEIDAARIIKQIL 177 Query: 619 SAV 627 S + Sbjct: 178 SGI 180
>KCC1D_MOUSE (Q8BW96) Calcium/calmodulin-dependent protein kinase type 1D (EC| 2.7.11.17) (CaM kinase ID) (CaM kinase I delta) (CaMKI-delta) (CaM-KI delta) (CaMKI delta) (Camk1D) (CamKI-like protein kinase) (CKLiK) (mCKLiK) Length = 385 Score = 66.6 bits (161), Expect = 6e-11 Identities = 35/112 (31%), Positives = 62/112 (55%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHKS 471 +E LG GAF +V A+ + + A+K + K+ + G + EI +R + H++ Sbjct: 23 FEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALK--GKESSIENEIAVLRKIKHEN 80 Query: 472 IVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 IV L ++ + + +Y VM+ + GGELFD++ + G TE A +Q++ AV Sbjct: 81 IVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAV 132
>KCC1D_HUMAN (Q8IU85) Calcium/calmodulin-dependent protein kinase type 1D (EC| 2.7.11.17) (CaM kinase ID) (CaM kinase I delta) (CaMKI-delta) (CaM-KI delta) (CaMKI delta) (Camk1D) (CamKI-like protein kinase) (CKLiK) Length = 385 Score = 66.6 bits (161), Expect = 6e-11 Identities = 35/112 (31%), Positives = 62/112 (55%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHKS 471 +E LG GAF +V A+ + + A+K + K+ + G + EI +R + H++ Sbjct: 23 FEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALK--GKESSIENEIAVLRKIKHEN 80 Query: 472 IVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 IV L ++ + + +Y VM+ + GGELFD++ + G TE A +Q++ AV Sbjct: 81 IVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAV 132
>DCAK2_HUMAN (Q8N568) Serine/threonine-protein kinase DCAMKL2 (EC 2.7.11.1)| (Doublecortin-like and CAM kinase-like 2) Length = 766 Score = 66.6 bits (161), Expect = 6e-11 Identities = 35/110 (31%), Positives = 65/110 (59%), Gaps = 2/110 (1%) Frame = +1 Query: 280 VMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLV 459 ++ +Y++G+++G G F V + + + A+K++DK G + E++ +R V Sbjct: 390 LLEKYKIGKVIGDGNFAVVKECIDRSTGKEFALKIIDKAKCC--GKEHLIENEVSILRRV 447 Query: 460 AHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTE--GAAHKY 603 H +I+ L E M T ++++ VME +KGG+LFD ++ + K TE G+A Y Sbjct: 448 KHPNIIMLVEEMETATELFLVMELVKGGDLFDAITSSTKYTERDGSAMVY 497
>CDPK3_ORYSA (P53684) Calcium-dependent protein kinase, isoform 11 (EC 2.7.11.1)| (CDPK 11) Length = 542 Score = 66.6 bits (161), Expect = 6e-11 Identities = 42/140 (30%), Positives = 69/140 (49%), Gaps = 9/140 (6%) Frame = +1 Query: 235 AVTYTLEGMENSGKIVMGR--------YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMD 390 A + G++ + V+GR Y +GR LG+G FG + + + A K + Sbjct: 52 AASILRRGLDPTSINVLGRKTADLREHYIIGRKLGQGQFGTTYLCTEINTGCEYACKTIP 111 Query: 391 KETVLKVGLAEQVRREITTMR-LVAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSK 567 K ++ E VRREI M L HK++V + +V ++ VME GGELFD++ + Sbjct: 112 KRKLITKEDVEDVRREIQIMHHLSGHKNVVAIKDVYEDGQAVHIVMELCAGGELFDRIQE 171 Query: 568 AGKLTEGAAHKYFQQLISAV 627 G +E A + + ++S V Sbjct: 172 KGHYSERKAAELIRIIVSIV 191
>KAPC_ENCCU (Q8SRK8) Probable cAMP-dependent protein kinase catalytic subunit| (EC 2.7.11.11) Length = 322 Score = 66.6 bits (161), Expect = 6e-11 Identities = 40/114 (35%), Positives = 65/114 (57%), Gaps = 2/114 (1%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGV-AIKMMDKETVLKVGLAEQVRREITTM-RLVAH 465 +E +++G GAFGKVH + S V A+KM+D +L+ LA+Q+ EI+ + R+ Sbjct: 7 FEFVKVVGVGAFGKVHLVRLKSSPTSVFAMKMLDFGEILRQRLADQLENEISILKRIYGC 66 Query: 466 KSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 + +L+ K+ +MEY+ GGELF + K G+ E A Y ++ISA+ Sbjct: 67 PFVAKLYSTDFHGGKVGLIMEYVGGGELFYWLKKCGRFDEQMARFYAAEIISAL 120
>KAPCB_RAT (P68182) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 66.6 bits (161), Expect = 6e-11 Identities = 34/109 (31%), Positives = 60/109 (55%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHKS 471 +E + LG G+FG+V K+ + + A+K++DK+ V+K+ E E ++ V Sbjct: 43 FERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVEFPF 102 Query: 472 IVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLI 618 +V+L S +Y VMEY+ GGE+F + + G+ +E A Y Q++ Sbjct: 103 LVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIV 151
>KAPCB_MOUSE (P68181) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 66.6 bits (161), Expect = 6e-11 Identities = 34/109 (31%), Positives = 60/109 (55%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHKS 471 +E + LG G+FG+V K+ + + A+K++DK+ V+K+ E E ++ V Sbjct: 43 FERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVEFPF 102 Query: 472 IVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLI 618 +V+L S +Y VMEY+ GGE+F + + G+ +E A Y Q++ Sbjct: 103 LVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIV 151
>KAPCB_CRIGR (P68180) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 66.6 bits (161), Expect = 6e-11 Identities = 34/109 (31%), Positives = 60/109 (55%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHKS 471 +E + LG G+FG+V K+ + + A+K++DK+ V+K+ E E ++ V Sbjct: 43 FERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVEFPF 102 Query: 472 IVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLI 618 +V+L S +Y VMEY+ GGE+F + + G+ +E A Y Q++ Sbjct: 103 LVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIV 151
>KAPCA_CRIGR (P25321) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 66.6 bits (161), Expect = 6e-11 Identities = 34/105 (32%), Positives = 58/105 (55%) Frame = +1 Query: 304 RLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHKSIVQL 483 + LG G+FG+V K+ E+ A+K++DK+ V+K+ E E ++ V +V+L Sbjct: 47 KTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKL 106 Query: 484 HEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLI 618 S +Y VMEY+ GGE+F + + G+ +E A Y Q++ Sbjct: 107 EFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIV 151
>DAPK3_RAT (O88764) Death-associated protein kinase 3 (EC 2.7.11.1) (DAP| kinase 3) (DAP-like kinase) (Dlk) (ZIP-kinase) Length = 448 Score = 66.6 bits (161), Expect = 6e-11 Identities = 35/119 (29%), Positives = 66/119 (55%), Gaps = 3/119 (2%) Frame = +1 Query: 280 VMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETV--LKVGLA-EQVRREITTM 450 V YE+G LG G F V + + A K + K + + G++ E++ RE++ + Sbjct: 9 VEDHYEMGEELGSGQFAIVRKCQQKGTGMEYAAKFIKKRRLPSSRRGVSREEIEREVSIL 68 Query: 451 RLVAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 R + H +I+ LH+V ++ + ++E + GGELFD +++ LTE A ++ +Q++ V Sbjct: 69 REIRHPNIITLHDVFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGV 127
>DAPK3_MOUSE (O54784) Death-associated protein kinase 3 (EC 2.7.11.1) (DAP| kinase 3) (DAP-like kinase) (Dlk) (ZIP-kinase) Length = 448 Score = 66.6 bits (161), Expect = 6e-11 Identities = 35/119 (29%), Positives = 66/119 (55%), Gaps = 3/119 (2%) Frame = +1 Query: 280 VMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETV--LKVGLA-EQVRREITTM 450 V YE+G LG G F V + + A K + K + + G++ E++ RE++ + Sbjct: 9 VEDHYEMGEELGSGQFAIVRKCQQKGTGMEYAAKFIKKRRLPSSRRGVSREEIEREVSIL 68 Query: 451 RLVAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 R + H +I+ LH+V ++ + ++E + GGELFD +++ LTE A ++ +Q++ V Sbjct: 69 REIRHPNIITLHDVFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGV 127
>PLK4_MOUSE (Q64702) Serine/threonine-protein kinase PLK4 (EC 2.7.11.21)| (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase Sak) (Serine/threonine-protein kinase 18) Length = 925 Score = 66.2 bits (160), Expect = 7e-11 Identities = 33/113 (29%), Positives = 65/113 (57%), Gaps = 1/113 (0%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHKS 471 +++G LLGKG+F V+ A+++ + VAIKM+DK+ + K G+ ++V+ E+ + H S Sbjct: 12 FKVGNLLGKGSFAGVYRAESIHTGLEVAIKMIDKKAMYKAGMVQRVQNEVKIHCQLKHPS 71 Query: 472 IVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGK-LTEGAAHKYFQQLISAV 627 +++L+ + +Y V+E GE+ + K +E A + Q+I+ + Sbjct: 72 VLELYNYFEDNNYVYLVLEMCHNGEMNRYLKNRMKPFSEREARHFMHQIITGM 124
>KS6A1_HUMAN (Q15418) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1)| (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 735 Score = 66.2 bits (160), Expect = 7e-11 Identities = 41/138 (29%), Positives = 72/138 (52%), Gaps = 3/138 (2%) Frame = +1 Query: 226 ILLAVTYTLEGMENSGKIVMGRYELGRLLGKGAFGKVHYAKNL---ESNRGVAIKMMDKE 396 +L ++ T S K +EL ++LG+G+FGKV + + +S A+K++ K Sbjct: 40 VLKEISITHHVKAGSEKADPSHFELLKVLGQGSFGKVFLVRKVTRPDSGHLYAMKVLKKA 99 Query: 397 TVLKVGLAEQVRREITTMRLVAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGK 576 T LKV + + E + V H +V+LH T K+Y ++++++GG+LF ++SK Sbjct: 100 T-LKVRDRVRTKMERDILADVNHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVM 158 Query: 577 LTEGAAHKYFQQLISAVD 630 TE Y +L +D Sbjct: 159 FTEEDVKFYLAELALGLD 176 Score = 42.0 bits (97), Expect = 0.001 Identities = 27/101 (26%), Positives = 49/101 (48%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHKS 471 Y + +G G++ + + +N A+K++DK K +E++ +R H + Sbjct: 418 YVVKETIGVGSYSECKRCVHKATNMEYAVKVIDKS---KRDPSEEIE---ILLRYGQHPN 471 Query: 472 IVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAA 594 I+ L +V +Y V E M+GGEL DK+ + +E A Sbjct: 472 IITLKDVYDDGKHVYLVTELMRGGELLDKILRQKFFSEREA 512
>CDPK_DAUCA (P28582) Calcium-dependent protein kinase (EC 2.7.11.1) (CDPK)| Length = 532 Score = 66.2 bits (160), Expect = 7e-11 Identities = 38/117 (32%), Positives = 62/117 (52%), Gaps = 1/117 (0%) Frame = +1 Query: 280 VMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMR-L 456 + G+Y LG+ LG+G FG V+ S + A K + K ++ E ++REI ++ L Sbjct: 77 IRGKYTLGKELGRGQFGCVYQCTENSSGQLYACKSILKRKLVSKNDKEDIKREIQILQHL 136 Query: 457 VAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 +IV+ V R ++ VME GGELFD++ G +E AA +Q+++ V Sbjct: 137 SGQPNIVEFKGVFEDRQSVHLVMELCAGGELFDRIIAQGHYSERAAATICRQIVNVV 193
>CHK1_HUMAN (O14757) Serine/threonine-protein kinase Chk1 (EC 2.7.11.1)| Length = 476 Score = 66.2 bits (160), Expect = 7e-11 Identities = 34/112 (30%), Positives = 65/112 (58%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHKS 471 ++L + LG+GA+G+V A N + VA+K++D + V E +++EI +++ H++ Sbjct: 9 WDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRA--VDCPENIKKEICINKMLNHEN 66 Query: 472 IVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 +V+ + + Y +EY GGELFD++ + E A ++F QL++ V Sbjct: 67 VVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGV 118
>KS6AA_XENLA (P10665) Ribosomal protein S6 kinase 2 alpha (EC 2.7.11.1)| (Ribosomal protein S6 kinase II alpha) (S6KII-alpha) (P90-RSK) (MAP kinase-activated protein kinase 1) (MAPK-activated protein kinase 1) (MAPKAP kinase 1) (MAPKAPK-1) Length = 733 Score = 65.9 bits (159), Expect = 1e-10 Identities = 39/126 (30%), Positives = 69/126 (54%), Gaps = 3/126 (2%) Frame = +1 Query: 262 ENSGKIVMGRYELGRLLGKGAFGKVHYAKNL---ESNRGVAIKMMDKETVLKVGLAEQVR 432 E S K + L ++LG+G+FGKV + + ++N+ A+K++ K T LKV + + Sbjct: 52 EGSEKADQSDFVLLKVLGQGSFGKVFLVRKITPPDANQLYAMKVLKKAT-LKVRDRVRTK 110 Query: 433 REITTMRLVAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQ 612 E + V H +V+LH T K+Y ++++++GG+LF ++SK TE Y + Sbjct: 111 MERDILADVHHPFVVRLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAE 170 Query: 613 LISAVD 630 L +D Sbjct: 171 LALGLD 176 Score = 40.0 bits (92), Expect = 0.006 Identities = 28/106 (26%), Positives = 50/106 (47%) Frame = +1 Query: 277 IVMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRL 456 + M Y + +G G++ + +N A+K++DK K +E++ R Sbjct: 411 LFMDVYTVRETIGVGSYSVCKRCVHKGTNMEYAVKVIDKT---KRDPSEEIE---ILRRY 464 Query: 457 VAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAA 594 H +I+ L +V + IY V E M+GGEL D++ + +E A Sbjct: 465 GQHPNIIALKDVYKEGNSIYVVTELMRGGELLDRILRQKFFSEREA 510
>KCC1_METAN (O14408) Calcium/calmodulin-dependent protein kinase (EC 2.7.11.17)| Length = 382 Score = 65.9 bits (159), Expect = 1e-10 Identities = 40/114 (35%), Positives = 62/114 (54%) Frame = +1 Query: 289 RYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHK 468 +Y+ GR LG G +G V A VAIK++ K+ V G + V E+ ++ + H Sbjct: 22 KYKFGRTLGAGTYGVVREADGPSGK--VAIKIILKKNVK--GNEKMVYAELDMLQRLTHP 77 Query: 469 SIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAVD 630 IV+ + +R K Y V + GGELFD++ GK TE A + +Q+++AVD Sbjct: 78 HIVKFVDWFESRDKFYIVTQLATGGELFDRICDQGKFTEVDASQTIRQIMTAVD 131
>KAPCB_PIG (P05383) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 65.9 bits (159), Expect = 1e-10 Identities = 34/109 (31%), Positives = 60/109 (55%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHKS 471 +E + LG G+FG+V K+ + + A+K++DK+ V+K+ E E ++ V Sbjct: 43 FERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPF 102 Query: 472 IVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLI 618 +V+L S +Y VMEY+ GGE+F + + G+ +E A Y Q++ Sbjct: 103 LVRLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIV 151
>AKT3_RAT (Q63484) RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-gamma) (Protein kinase Akt-3) (Protein kinase B, gamma) (PKB gamma) Length = 454 Score = 65.9 bits (159), Expect = 1e-10 Identities = 35/116 (30%), Positives = 59/116 (50%) Frame = +1 Query: 283 MGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVA 462 M ++ +LLGKG FGKV + S + A+K++ KE ++ E ++ Sbjct: 145 MNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTR 204 Query: 463 HKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAVD 630 H + L T+ ++ FVMEY+ GGELF +S+ +E Y +++SA+D Sbjct: 205 HPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALD 260
>CHK1_MOUSE (O35280) Serine/threonine-protein kinase Chk1 (EC 2.7.11.1)| Length = 476 Score = 65.9 bits (159), Expect = 1e-10 Identities = 33/112 (29%), Positives = 65/112 (58%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHKS 471 ++L + LG+GA+G+V A N + VA+K++D + + E +++EI ++++H++ Sbjct: 9 WDLVQTLGEGAYGEVQLAVNRITEEAVAVKIVDMKRA--IDCPENIKKEICINKMLSHEN 66 Query: 472 IVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 +V+ + Y +EY GGELFD++ + E A ++F QL++ V Sbjct: 67 VVKFYGHRREGHIQYLFLEYCSGGELFDRIEPDIGMPEQDAQRFFHQLMAGV 118
>KAPC_DICDI (P34099) cAMP-dependent protein kinase catalytic subunit (EC| 2.7.11.11) Length = 648 Score = 65.9 bits (159), Expect = 1e-10 Identities = 32/109 (29%), Positives = 60/109 (55%) Frame = +1 Query: 304 RLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHKSIVQL 483 R+LG G FGKV+ +N + A+K ++K V+++ E + E + + + H IV L Sbjct: 340 RVLGTGTFGKVYLIQNTKDGCYYAMKCLNKAYVVQLKQVEHLNSEKSILSSIHHPFIVNL 399 Query: 484 HEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAVD 630 ++ K+Y + EY+ GGE+F + K+ K + A Y +++ A++ Sbjct: 400 YQAFQDEKKLYLLFEYVAGGEVFTHLRKSMKFSNSTAKFYAAEIVLALE 448
>AKT3_MOUSE (Q9WUA6) RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-gamma) (Protein kinase Akt-3) (Protein kinase B, gamma) (PKB gamma) Length = 479 Score = 65.9 bits (159), Expect = 1e-10 Identities = 35/116 (30%), Positives = 59/116 (50%) Frame = +1 Query: 283 MGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVA 462 M ++ +LLGKG FGKV + S + A+K++ KE ++ E ++ Sbjct: 145 MNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTR 204 Query: 463 HKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAVD 630 H + L T+ ++ FVMEY+ GGELF +S+ +E Y +++SA+D Sbjct: 205 HPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALD 260
>AKT3_HUMAN (Q9Y243) RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-gamma) (Protein kinase Akt-3) (Protein kinase B, gamma) (PKB gamma) (STK-2) Length = 479 Score = 65.9 bits (159), Expect = 1e-10 Identities = 35/116 (30%), Positives = 59/116 (50%) Frame = +1 Query: 283 MGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVA 462 M ++ +LLGKG FGKV + S + A+K++ KE ++ E ++ Sbjct: 145 MNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTR 204 Query: 463 HKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAVD 630 H + L T+ ++ FVMEY+ GGELF +S+ +E Y +++SA+D Sbjct: 205 HPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALD 260
>KCC1A_HUMAN (Q14012) Calcium/calmodulin-dependent protein kinase type 1 (EC| 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha) Length = 370 Score = 65.5 bits (158), Expect = 1e-10 Identities = 36/112 (32%), Positives = 62/112 (55%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHKS 471 Y+ +LG GAF +V A++ + + VAIK + KE + G + EI + + H + Sbjct: 20 YDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKEAL--EGKEGSMENEIAVLHKIKHPN 77 Query: 472 IVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 IV L ++ + +Y +M+ + GGELFD++ + G TE A + Q++ AV Sbjct: 78 IVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAV 129
>IPL1_CANAL (Q59S66) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 530 Score = 65.5 bits (158), Expect = 1e-10 Identities = 34/118 (28%), Positives = 62/118 (52%) Frame = +1 Query: 274 KIVMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMR 453 ++ + +E G++LGKG G+V+ K+ +S A+K+M K ++ + L + +RREI Sbjct: 238 QLTLDDFEFGKILGKGKLGRVYCVKHKQSGLIFALKVMSKSEIMNLKLEKSLRREIEIQS 297 Query: 454 LVAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 + H +I +L+ IY ++EY GEL+ + K + A Y Q+ A+ Sbjct: 298 NLYHINITRLYSWFHDSINIYLLLEYSIEGELYTHLKKLKRFDNIMASNYIFQITQAL 355
>KS6A1_RAT (Q63531) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1)| (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 735 Score = 65.5 bits (158), Expect = 1e-10 Identities = 41/138 (29%), Positives = 72/138 (52%), Gaps = 3/138 (2%) Frame = +1 Query: 226 ILLAVTYTLEGMENSGKIVMGRYELGRLLGKGAFGKVHYAKNL---ESNRGVAIKMMDKE 396 IL ++ T S K +EL ++LG+G+FGKV + + ++ A+K++ K Sbjct: 40 ILKEISITHHVKAGSEKADPSHFELLKVLGQGSFGKVFLVRKVTRPDNGHLYAMKVLKKA 99 Query: 397 TVLKVGLAEQVRREITTMRLVAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGK 576 T LKV + + E + V H +V+LH T K+Y ++++++GG+LF ++SK Sbjct: 100 T-LKVRDRVRTKMERDILADVNHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVM 158 Query: 577 LTEGAAHKYFQQLISAVD 630 TE Y +L +D Sbjct: 159 FTEEDVKFYLAELALGLD 176 Score = 40.8 bits (94), Expect = 0.003 Identities = 27/101 (26%), Positives = 48/101 (47%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHKS 471 Y + +G G++ + +N A+K++DK K +E++ +R H + Sbjct: 418 YIVKETIGVGSYSVCKRCVHKATNMEYAVKVIDKS---KRDPSEEIE---ILLRYGQHPN 471 Query: 472 IVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAA 594 I+ L +V +Y V E M+GGEL DK+ + +E A Sbjct: 472 IITLKDVYDDSKHVYLVTELMRGGELLDKILRQKFFSEREA 512
>ZYG1_CAEBR (Q621J7) Probable serine/threonine-protein kinase zyg-1 (EC| 2.7.11.1) (Zygote defective protein 1) Length = 709 Score = 65.5 bits (158), Expect = 1e-10 Identities = 41/109 (37%), Positives = 61/109 (55%), Gaps = 3/109 (2%) Frame = +1 Query: 310 LGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAE---QVRREITTMRLVAHKSIVQ 480 +G+G FG V+ A+ E+ VAIK K+G A +++ EI TM+L+ H++IVQ Sbjct: 19 IGQGGFGVVYSAQR-ENGEKVAIK--------KIGNAASQTRIKEEIKTMKLLRHRNIVQ 69 Query: 481 LHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 +E + Y VME +GG L D V + G L + A +QLI+AV Sbjct: 70 FYETFFENGETYLVMELCEGGSLMDYVKQKGPLDDSTAVHILRQLIAAV 118
>CHK1_RAT (Q91ZN7) Serine/threonine-protein kinase Chk1 (EC 2.7.11.1)| Length = 476 Score = 65.5 bits (158), Expect = 1e-10 Identities = 33/112 (29%), Positives = 65/112 (58%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHKS 471 ++L + LG+GA+G+V A N + VA+K++D + + E +++EI +++ H++ Sbjct: 9 WDLVQTLGEGAYGEVQLAVNRITEEAVAVKIVDMKRA--IDCPENIKKEICINKMLNHEN 66 Query: 472 IVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 +V+ + + Y +EY GGELFD++ + E A ++F QL++ V Sbjct: 67 VVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEQDAQRFFHQLMAGV 118
>KIN1_SCHPO (P22987) Protein kinase kin1 (EC 2.7.11.1)| Length = 891 Score = 65.5 bits (158), Expect = 1e-10 Identities = 43/147 (29%), Positives = 73/147 (49%), Gaps = 18/147 (12%) Frame = +1 Query: 241 TYTLEGMENSGKIVMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDK--ETVLKVG 414 +Y+ + + V+G Y LG+ +G G+ GKV A +L++ AIK++ + + K Sbjct: 108 SYSADEKPRERRKVIGNYVLGKTIGAGSMGKVKVAHHLKTGEQFAIKIVTRLHPDITKAK 167 Query: 415 LA----------EQVRREITTMR------LVAHKSIVQLHEVMATRSKIYFVMEYMKGGE 546 A + +EI T+R L+ H I + +V T S Y V E++ GG+ Sbjct: 168 AAASAEATKAAQSEKNKEIRTVREAALSTLLRHPYICEARDVYITNSHYYMVFEFVDGGQ 227 Query: 547 LFDKVSKAGKLTEGAAHKYFQQLISAV 627 + D + GKL E A K+ +Q+ SA+ Sbjct: 228 MLDYIISHGKLKEKQARKFVRQIGSAL 254
>CDPK2_MAIZE (P49101) Calcium-dependent protein kinase 2 (EC 2.7.11.1) (CDPK 2)| Length = 513 Score = 65.5 bits (158), Expect = 1e-10 Identities = 37/114 (32%), Positives = 58/114 (50%), Gaps = 1/114 (0%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMR-LVAHK 468 Y G+ LG+G FG + + S R A K + K ++ E +RREI M+ L Sbjct: 65 YSFGKELGRGQFGVTYLCTEIASGRQYACKSISKRKLVSKADREDIRREIQIMQHLSGQP 124 Query: 469 SIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAVD 630 +IV+ +S ++ VME GGELFD++ G TE AA + +++ V+ Sbjct: 125 NIVEFRGAYEDKSNVHVVMELCAGGELFDRIIAKGHYTERAAATICRAVVNVVN 178
>KS6AB_XENLA (P10666) Ribosomal protein S6 kinase 2 beta (EC 2.7.11.1)| (Ribosomal protein S6 kinase II beta) (S6KII-beta) (P90-RSK) Length = 629 Score = 65.5 bits (158), Expect = 1e-10 Identities = 38/126 (30%), Positives = 69/126 (54%), Gaps = 3/126 (2%) Frame = +1 Query: 262 ENSGKIVMGRYELGRLLGKGAFGKVHYAKNL---ESNRGVAIKMMDKETVLKVGLAEQVR 432 E + K + L ++LG+G+FGKV + + ++N+ A+K++ K T LKV + + Sbjct: 52 EGAEKADQSHFVLLKVLGQGSFGKVFLVRKITPPDANQLYAMKVLKKAT-LKVRDRVRTK 110 Query: 433 REITTMRLVAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQ 612 E + V H +V+LH T K+Y ++++++GG+LF ++SK TE Y + Sbjct: 111 MERDILADVHHPFVVRLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAE 170 Query: 613 LISAVD 630 L +D Sbjct: 171 LALGLD 176 Score = 39.7 bits (91), Expect = 0.007 Identities = 27/101 (26%), Positives = 48/101 (47%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHKS 471 Y + +G G++ + +N A+K++DK K +E++ R H + Sbjct: 416 YTVRETIGVGSYSVCKRCVHKGTNMEYAVKVIDKS---KRDPSEEIE---ILRRYGQHPN 469 Query: 472 IVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAA 594 I+ L +V + IY V E M+GGEL D++ + +E A Sbjct: 470 IITLKDVYEECNSIYLVTELMRGGELLDRILRQKFFSEREA 510
>CDPK2_ORYSA (P53683) Calcium-dependent protein kinase, isoform 2 (EC 2.7.11.1)| (CDPK 2) Length = 533 Score = 65.1 bits (157), Expect = 2e-10 Identities = 36/114 (31%), Positives = 60/114 (52%), Gaps = 1/114 (0%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMR-LVAHK 468 Y LG+ LG+G FG + + S + A K + K ++ E +RREI M+ L + Sbjct: 85 YSLGKELGRGQFGVTYLCTEIASGKQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQQ 144 Query: 469 SIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAVD 630 +IV+ +S ++ VME GGELFD++ G +E AA + +++ V+ Sbjct: 145 NIVEFRGAYEDKSNVHVVMELCAGGELFDRIIAKGHYSERAAATICRAVVNVVN 198
>STK11_HUMAN (Q15831) Serine/threonine-protein kinase 11 (EC 2.7.11.1)| (Serine/threonine-protein kinase LKB1) (NY-REN-19 antigen) Length = 433 Score = 65.1 bits (157), Expect = 2e-10 Identities = 41/122 (33%), Positives = 73/122 (59%), Gaps = 5/122 (4%) Frame = +1 Query: 280 VMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAE-QVRREITTMRL 456 ++G+Y +G LLG+G++GKV + E+ A+K++ K+ + ++ E V++EI +R Sbjct: 45 LIGKYLMGDLLGEGSYGKVKEVLDSETLCRRAVKILKKKKLRRIPNGEANVKKEIQLLRR 104 Query: 457 VAHKSIVQLHEVM--ATRSKIYFVMEYMKGG--ELFDKVSKAGKLTEGAAHKYFQQLISA 624 + HK+++QL +V+ + K+Y VMEY G E+ D V + + AH YF QLI Sbjct: 105 LRHKNVIQLVDVLYNEEKQKMYMVMEYCVCGMQEMLDSVPEK-RFPVCQAHGYFCQLIDG 163 Query: 625 VD 630 ++ Sbjct: 164 LE 165
>DCAK2_MOUSE (Q6PGN3) Serine/threonine-protein kinase DCAMKL2 (EC 2.7.11.1)| (Doublecortin-like and CAM kinase-like 2) Length = 756 Score = 65.1 bits (157), Expect = 2e-10 Identities = 35/110 (31%), Positives = 63/110 (57%), Gaps = 2/110 (1%) Frame = +1 Query: 280 VMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLV 459 ++ +Y +G+++G G F V + + + A+K++DK G + E++ +R V Sbjct: 389 LLEKYRIGKVIGDGNFAVVKECVDRYTGKEFALKIIDKAKCC--GKEHLIENEVSILRRV 446 Query: 460 AHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTE--GAAHKY 603 H +I+ L E M T + ++ VME +KGG+LFD ++ + K TE G+A Y Sbjct: 447 KHPNIIMLVEEMETATDLFLVMELVKGGDLFDAITSSTKYTERDGSAMVY 496
>AKT2B_XENLA (Q6IP76) RAC-beta serine/threonine-protein kinase-B (EC 2.7.11.1)| (RAC-PK-beta-B) (Protein kinase Akt-2-B) (Protein kinase B, beta-B) (PKB beta-B) Length = 485 Score = 65.1 bits (157), Expect = 2e-10 Identities = 36/119 (30%), Positives = 59/119 (49%) Frame = +1 Query: 274 KIVMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMR 453 K+ M ++ +LLGKG FGKV + + A+K++ KE ++ E ++ Sbjct: 150 KVTMNDFDYLKLLGKGTFGKVILVREKATGLYYAMKILRKEVIIAKDEVAHTLTESRVLQ 209 Query: 454 LVAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAVD 630 H + L T ++ FVMEY GGELF +S+ TE A Y +++SA++ Sbjct: 210 NTKHPFLTGLKYAFQTSDRLCFVMEYANGGELFFHLSRERVFTEDRARFYGAEIVSALE 268
>SSP1_SCHPO (P50526) Serine/threonine-protein kinase ssp1 (EC 2.7.11.1)| Length = 652 Score = 65.1 bits (157), Expect = 2e-10 Identities = 42/130 (32%), Positives = 74/130 (56%), Gaps = 9/130 (6%) Frame = +1 Query: 268 SGKIVMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDK-ETVLKVGLA------EQ 426 SG+ + YE+ + LG+G GKV ++ + +AIK++ K E K+G A E+ Sbjct: 127 SGRKYINHYEIIKELGRGMHGKVKLGRDTVTRELLAIKIIPKTERRPKLGRANASSQKEK 186 Query: 427 VRREITTMRLVAHKSIVQLHEVM--ATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHK 600 VRREI ++ H ++V+L EV+ + +K+Y V+EYM GGE+ + L+ A + Sbjct: 187 VRREIAILKKCVHPNVVRLREVIDDPSSTKVYLVLEYMSGGEVPWTDCDSPVLSISEARQ 246 Query: 601 YFQQLISAVD 630 YF+ ++ ++ Sbjct: 247 YFRDVVLGLE 256
>CDPK1_ORYSA (P53682) Calcium-dependent protein kinase, isoform 1 (EC 2.7.11.1)| (CDPK 1) Length = 534 Score = 64.7 bits (156), Expect = 2e-10 Identities = 38/114 (33%), Positives = 57/114 (50%), Gaps = 1/114 (0%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMR-LVAHK 468 Y LGR LG+G FGK + + + A K + K + V E VRREI M L K Sbjct: 73 YTLGRELGQGQFGKTYLCTEISTGCQYACKTILKSNLRCVSDIEDVRREIQIMHHLSGQK 132 Query: 469 SIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAVD 630 +IV + + ++ VME GGELF K+ K G +E A + + ++ ++ Sbjct: 133 NIVTIKDTYEDEQAVHIVMELCAGGELFSKIQKRGHYSERKAAELIKIIVGIIE 186
>KS6A2_MOUSE (Q9WUT3) Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1)| (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (Protein-tyrosine kinase Mpk-9) (MAP kinase-activated protein kinase 1c) (M Length = 733 Score = 64.7 bits (156), Expect = 2e-10 Identities = 40/129 (31%), Positives = 72/129 (55%), Gaps = 3/129 (2%) Frame = +1 Query: 253 EGMENSGKIVMGRYELGRLLGKGAFGKVHYAKNL---ESNRGVAIKMMDKETVLKVGLAE 423 EG E + ++EL ++LG+G++GKV + + ++ + A+K++ K T LKV Sbjct: 49 EGFEKADP---SQFELLKVLGQGSYGKVFLVRKVTGSDAGQLYAMKVLKKAT-LKVRDRV 104 Query: 424 QVRREITTMRLVAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKY 603 + + E + V H IV+LH T K+Y ++++++GG+LF ++SK TE Y Sbjct: 105 RSKMERDILAEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFY 164 Query: 604 FQQLISAVD 630 +L A+D Sbjct: 165 LAELALALD 173 Score = 42.4 bits (98), Expect = 0.001 Identities = 28/113 (24%), Positives = 53/113 (46%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHKS 471 YE+ +G G++ + ++ A+K++DK K +E++ +R H + Sbjct: 415 YEIKEDIGVGSYSVCKRCVHKATDAEYAVKIIDKS---KRDPSEEIE---ILLRYGQHPN 468 Query: 472 IVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAVD 630 I+ L +V +Y VME M+GGEL D++ + +E A + +D Sbjct: 469 IITLKDVYDDGKYVYLVMELMRGGELLDRILRQRCFSEREASDVLYTIARTMD 521
>KS6A2_HUMAN (Q15349) Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1)| (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (MAP kinase-activated protein kinase 1c) (MAPKAPK1C) Length = 733 Score = 64.7 bits (156), Expect = 2e-10 Identities = 40/129 (31%), Positives = 71/129 (55%), Gaps = 3/129 (2%) Frame = +1 Query: 253 EGMENSGKIVMGRYELGRLLGKGAFGKVHYAKNLESNRG---VAIKMMDKETVLKVGLAE 423 EG E + ++EL ++LG+G++GKV + ++ + A+K++ K T LKV Sbjct: 49 EGFEKADP---SQFELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKAT-LKVRDRV 104 Query: 424 QVRREITTMRLVAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKY 603 + + E + V H IV+LH T K+Y ++++++GG+LF ++SK TE Y Sbjct: 105 RSKMERDILAEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFY 164 Query: 604 FQQLISAVD 630 +L A+D Sbjct: 165 LAELALALD 173 Score = 42.0 bits (97), Expect = 0.001 Identities = 28/113 (24%), Positives = 53/113 (46%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHKS 471 YE+ +G G++ + ++ A+K++DK K +E++ +R H + Sbjct: 415 YEIKEDIGVGSYSVCKRCVHKATDTEYAVKIIDKS---KRDPSEEIE---ILLRYGQHPN 468 Query: 472 IVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAVD 630 I+ L +V +Y VME M+GGEL D++ + +E A + +D Sbjct: 469 IITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMD 521
>PLK3_CAEEL (Q20845) Serine/threonine-protein kinase plk-3 (EC 2.7.11.21)| (Polo-like kinase 3) Length = 615 Score = 64.7 bits (156), Expect = 2e-10 Identities = 35/112 (31%), Positives = 55/112 (49%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHKS 471 YE G LG+G F + L+ N +A+K++ K +LK E++ RE+ R ++H++ Sbjct: 35 YEKGAFLGEGGFAHCFEFRKLDCNDRLAVKVVPKVILLKSTAREKLTREVEIHRQLSHRN 94 Query: 472 IVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 IVQ H +YF +E L + + G LTE A Y Q+ V Sbjct: 95 IVQFHHFFEDSQNVYFTLELCSKNSLMELNKQRGPLTEHEARFYTIQVAEGV 146
>AKT1_DROME (Q8INB9) RAC serine/threonine-protein kinase (EC 2.7.11.1)| (DRAC-PK) (Akt) (Dakt1) (Protein kinase B) (PKB) Length = 611 Score = 64.7 bits (156), Expect = 2e-10 Identities = 35/118 (29%), Positives = 60/118 (50%) Frame = +1 Query: 274 KIVMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMR 453 K+ + +E ++LGKG FGKV + + + AIK++ KE +++ E ++ Sbjct: 260 KVTLENFEFLKVLGKGTFGKVILCREKATAKLYAIKILKKEVIIQKDEVAHTLTESRVLK 319 Query: 454 LVAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 H ++ L T ++ FVM+Y+ GGELF +S TE Y ++ISA+ Sbjct: 320 STNHPFLISLKYSFQTNDRLCFVMQYVNGGELFWHLSHERIFTEDRTRFYGAEIISAL 377
>KAPCG_MACMU (O62846) cAMP-dependent protein kinase, gamma-catalytic subunit (EC| 2.7.11.11) (PKA C-gamma) (Fragment) Length = 208 Score = 64.3 bits (155), Expect = 3e-10 Identities = 32/112 (28%), Positives = 62/112 (55%) Frame = +1 Query: 289 RYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHK 468 ++E + LG G++G+V ++ E+ A+K++DK+ V+++ E E ++ + Sbjct: 41 QFERLKTLGTGSYGRVMLVRHRETGNHYAMKILDKQKVVRLKQVEHTLNEKRILQAINFP 100 Query: 469 SIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISA 624 +V+L S +Y VMEY+ GGE+F + + G+ +E A Y Q++ A Sbjct: 101 FLVKLQFSFKDNSNLYLVMEYVPGGEMFSHLRRVGRFSEPQACFYAAQVVLA 152
>DAPK2_MOUSE (Q8VDF3) Death-associated protein kinase 2 (EC 2.7.11.1) (DAP| kinase 2) (DAP-kinase-related protein 1) (DRP-1) Length = 370 Score = 64.3 bits (155), Expect = 3e-10 Identities = 34/116 (29%), Positives = 63/116 (54%), Gaps = 3/116 (2%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKET--VLKVGLA-EQVRREITTMRLVA 462 Y++G LG G F V + + A K + K + G+ E++ RE++ +R V Sbjct: 23 YDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVCREEIEREVSILRQVL 82 Query: 463 HKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAVD 630 H +I+ LH+V R+ + ++E + GGELFD +++ L+E A + +Q++ V+ Sbjct: 83 HPNIITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEATSFIKQILDGVN 138
>DAPK2_HUMAN (Q9UIK4) Death-associated protein kinase 2 (EC 2.7.11.1) (DAP| kinase 2) (DAP-kinase-related protein 1) (DRP-1) Length = 370 Score = 64.3 bits (155), Expect = 3e-10 Identities = 33/116 (28%), Positives = 64/116 (55%), Gaps = 3/116 (2%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKET--VLKVGLA-EQVRREITTMRLVA 462 Y++G LG G F V + + A K + K + G++ E++ RE++ +R V Sbjct: 23 YDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVSREEIEREVSILRQVL 82 Query: 463 HKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAVD 630 H +++ LH+V R+ + ++E + GGELFD +++ L+E A + +Q++ V+ Sbjct: 83 HHNVITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEATSFIKQILDGVN 138
>CHK1_DROME (O61661) Serine/threonine-protein kinase grp (EC 2.7.11.1) (Protein| grapes) (Chk1 homolog) Length = 512 Score = 64.3 bits (155), Expect = 3e-10 Identities = 35/113 (30%), Positives = 62/113 (54%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHKS 471 + L + LG+GA+G+V N ++ VA+KM+D + A VR+E+ +++ K Sbjct: 22 WTLAQTLGEGAYGEVKLLINRQTGEAVAMKMVDLKK--HPDAANSVRKEVCIQKMLQDKH 79 Query: 472 IVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAVD 630 I++ + S Y +EY GGELFD++ + + A +YF QL+S ++ Sbjct: 80 ILRFFGKRSQGSVEYIFLEYAAGGELFDRIEPDVGMPQHEAQRYFTQLLSGLN 132
>KDC2_DROME (P16912) Protein kinase DC2 (EC 2.7.11.1)| Length = 583 Score = 64.3 bits (155), Expect = 3e-10 Identities = 31/113 (27%), Positives = 62/113 (54%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHKS 471 Y++ + +G G FG+V ++ S + A+K++ V+++ E V+ E +R + H Sbjct: 274 YQIIKTVGTGTFGRVCLCRDRISEKYCAMKILAMTEVIRLKQIEHVKNERNILREIRHPF 333 Query: 472 IVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAVD 630 ++ L S +Y + +Y+ GGELF + AGK T ++ Y +++SA++ Sbjct: 334 VISLEWSTKDDSNLYMIFDYVCGGELFTYLRNAGKFTSQTSNFYAAEIVSALE 386
>CDR1_SCHPO (P07334) Mitosis inducer protein kinase cdr1 (EC 2.7.11.1) (Protein| kinase nim1) Length = 593 Score = 64.3 bits (155), Expect = 3e-10 Identities = 39/118 (33%), Positives = 63/118 (53%) Frame = +1 Query: 274 KIVMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMR 453 K +G + LG+ LG G+ V AK+ ++ AIK ++ + A + EI MR Sbjct: 6 KNTIGVWRLGKTLGTGSTSCVRLAKHAKTGDLAAIK------IIPIRYAS-IGMEILMMR 58 Query: 454 LVAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 L+ H +I++L++V +Y +EY+ GELF + K G L+E A Y Q++ AV Sbjct: 59 LLRHPNILRLYDVWTDHQHMYLALEYVPDGELFHYIRKHGPLSEREAAHYLSQILDAV 116
>KCC1G_MOUSE (Q91VB2) Calcium/calmodulin-dependent protein kinase type 1G (EC| 2.7.11.17) (CaM kinase IG) (CaM kinase I gamma) (CaMKI gamma) (CaMKI-gamma) (CaM-KI gamma) (CaMKIG) (CaMK-like CREB kinase III) (CLICK III) Length = 477 Score = 63.9 bits (154), Expect = 4e-10 Identities = 35/107 (32%), Positives = 58/107 (54%) Frame = +1 Query: 307 LLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHKSIVQLH 486 +LG GAF +V K + + A+K + K + E EI ++ + H++IV L Sbjct: 28 VLGSGAFSEVFLVKQRVTGKLFALKCIKKSPAFRDSSLEN---EIAVLKRIKHENIVTLE 84 Query: 487 EVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 ++ + + Y VM+ + GGELFD++ + G TE A QQ++SAV Sbjct: 85 DIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAV 131
>KCC1A_RAT (Q63450) Calcium/calmodulin-dependent protein kinase type 1 (EC| 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha) Length = 374 Score = 63.9 bits (154), Expect = 4e-10 Identities = 35/112 (31%), Positives = 62/112 (55%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHKS 471 Y+ +LG GAF +V A++ + + VAIK + K+ + G + EI + + H + Sbjct: 20 YDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKKAL--EGKEGSMENEIAVLHKIKHPN 77 Query: 472 IVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 IV L ++ + +Y +M+ + GGELFD++ + G TE A + Q++ AV Sbjct: 78 IVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAV 129
>KCC1A_MOUSE (Q91YS8) Calcium/calmodulin-dependent protein kinase type 1 (EC| 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha) Length = 374 Score = 63.9 bits (154), Expect = 4e-10 Identities = 35/112 (31%), Positives = 62/112 (55%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHKS 471 Y+ +LG GAF +V A++ + + VAIK + K+ + G + EI + + H + Sbjct: 20 YDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKKAL--EGKEGSMENEIAVLHKIKHPN 77 Query: 472 IVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 IV L ++ + +Y +M+ + GGELFD++ + G TE A + Q++ AV Sbjct: 78 IVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAV 129
>KS6A5_CHICK (Q5F3L1) Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1)| Length = 789 Score = 63.9 bits (154), Expect = 4e-10 Identities = 39/142 (27%), Positives = 76/142 (53%), Gaps = 8/142 (5%) Frame = +1 Query: 229 LLAVTYTLEGMENSG---KIVMGRYELGRLLGKGAFGKVHYAKNL---ESNRGVAIKMMD 390 LL VT+ L +G K+ + +EL ++LG GA+GKV + + ++ + A+K++ Sbjct: 15 LLTVTHELRNANLTGHAEKVGIENFELLKVLGTGAYGKVFLVRKVSGHDAGKLYAMKVLK 74 Query: 391 KETVL-KVGLAEQVRREITTMRLVAHKS-IVQLHEVMATRSKIYFVMEYMKGGELFDKVS 564 K T++ K E R E + + +V LH T +K++ +++Y+ GGELF +S Sbjct: 75 KATIVQKAKTTEHTRTERQVLEHIRQSPFLVTLHYAFQTDTKLHLILDYINGGELFTHLS 134 Query: 565 KAGKLTEGAAHKYFQQLISAVD 630 + + +E Y +++ A++ Sbjct: 135 QRERFSENEVQIYIGEIVLALE 156 Score = 58.5 bits (140), Expect = 2e-08 Identities = 33/107 (30%), Positives = 60/107 (56%), Gaps = 1/107 (0%) Frame = +1 Query: 310 LGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLV-AHKSIVQLH 486 LG+G+F + ++++ A+K++ K + +REIT ++L H ++V+LH Sbjct: 422 LGEGSFSICRKCLHKKTSQEYAVKIISKR------MEANTQREITALKLCEGHPNVVKLH 475 Query: 487 EVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 EV + + VME +KGGEL +++ K +E A ++L+SAV Sbjct: 476 EVYHDQLHTFLVMELLKGGELLERIQKKQHFSETEASHIMRRLVSAV 522
>KCC1G_RAT (Q7TNJ7) Calcium/calmodulin-dependent protein kinase type 1G (EC| 2.7.11.17) (CaM kinase IG) (CaM kinase I gamma) (CaMKI gamma) (CaMKI-gamma) (CaM-KI gamma) (CaMKIG) (CaMK-like CREB kinase III) (CLICK III) Length = 476 Score = 63.9 bits (154), Expect = 4e-10 Identities = 35/107 (32%), Positives = 58/107 (54%) Frame = +1 Query: 307 LLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHKSIVQLH 486 +LG GAF +V K + + A+K + K + E EI ++ + H++IV L Sbjct: 28 VLGSGAFSEVFLVKQRVTGKLFALKCIKKSPAFRDSSLEN---EIAVLKRIKHENIVTLE 84 Query: 487 EVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 ++ + + Y VM+ + GGELFD++ + G TE A QQ++SAV Sbjct: 85 DIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAV 131
>KPC2_APLCA (Q16975) Calcium-independent protein kinase C (EC 2.7.11.13) (APL| II) Length = 743 Score = 63.9 bits (154), Expect = 4e-10 Identities = 36/119 (30%), Positives = 65/119 (54%), Gaps = 1/119 (0%) Frame = +1 Query: 274 KIVMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMR 453 +I + + ++LGKG+FGKV A+ ++ AIK++ K+ +++ E E + Sbjct: 397 RISLHDFNFIKVLGKGSFGKVMLAEKKGTDEVYAIKVLKKDVIIQDDDVECTMTEKRILA 456 Query: 454 LVA-HKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 L A H + LH T+ +++FVMEY+ GG+L ++ +A K E A Y ++ A+ Sbjct: 457 LSAKHPFLTALHSSFQTKERLFFVMEYVNGGDLMFQIQRARKFDEPRARFYAAEVTLAL 515
>SGK1_RAT (Q06226) Serine/threonine-protein kinase Sgk1 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 1) Length = 430 Score = 63.5 bits (153), Expect = 5e-10 Identities = 35/109 (32%), Positives = 60/109 (55%), Gaps = 1/109 (0%) Frame = +1 Query: 304 RLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTM-RLVAHKSIVQ 480 +++GKG+FGKV A++ A+K++ K+ +LK + + E + + V H +V Sbjct: 102 KVIGKGSFGKVLLARHKAEEAFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLVG 161 Query: 481 LHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 LH T K+YFV++Y+ GGELF + + E A Y ++ SA+ Sbjct: 162 LHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASAL 210
>SGK1_RABIT (Q9XT18) Serine/threonine-protein kinase Sgk1 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 1) Length = 431 Score = 63.5 bits (153), Expect = 5e-10 Identities = 35/109 (32%), Positives = 60/109 (55%), Gaps = 1/109 (0%) Frame = +1 Query: 304 RLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTM-RLVAHKSIVQ 480 +++GKG+FGKV A++ A+K++ K+ +LK + + E + + V H +V Sbjct: 102 KVIGKGSFGKVLLARHKAEEAFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLVG 161 Query: 481 LHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 LH T K+YFV++Y+ GGELF + + E A Y ++ SA+ Sbjct: 162 LHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASAL 210
>KPC1B_CAEEL (P34885) Protein kinase C-like 1B (EC 2.7.11.13) (PKC1B)| Length = 707 Score = 63.5 bits (153), Expect = 5e-10 Identities = 36/120 (30%), Positives = 64/120 (53%), Gaps = 1/120 (0%) Frame = +1 Query: 271 GKIVMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTM 450 G + + + ++LGKG+FGKV A+ ++ AIK++ K+ +++ E E + Sbjct: 371 GTLSIHDFTFMKVLGKGSFGKVMLAERKGTDEVYAIKILKKDVIVQDDDVECTMCEKRIL 430 Query: 451 RLVA-HKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 L A H + LH T +++FVMEY+ GG+L ++ +A K E A Y ++ A+ Sbjct: 431 SLAAKHPFLTALHSSFQTSDRLFFVMEYVNGGDLMFQIQRARKFDESRARFYAAEVTCAL 490
>DAPK1_MOUSE (Q80YE7) Death-associated protein kinase 1 (EC 2.7.11.1) (DAP| kinase 1) Length = 1442 Score = 63.5 bits (153), Expect = 5e-10 Identities = 33/115 (28%), Positives = 63/115 (54%), Gaps = 3/115 (2%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVL--KVGLA-EQVRREITTMRLVA 462 Y+ G LG G F V + + A K + K + G++ E + RE++ ++ + Sbjct: 13 YDTGEELGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRGVSREDIEREVSILKEIR 72 Query: 463 HKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 H +++ LHEV ++ + ++E + GGELFD +++ LTE A ++ +Q++S V Sbjct: 73 HPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQILSGV 127
>Y31E_CAEEL (Q8MYQ1) Putative serine/threonine-protein kinase F31E3.2 (EC| 2.7.11.1) Length = 441 Score = 63.5 bits (153), Expect = 5e-10 Identities = 40/117 (34%), Positives = 65/117 (55%), Gaps = 4/117 (3%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNL-ESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLV-AH 465 + L R LG+G+FG V+ A + +S R AIKM +K ++ QV+RE + RL+ +H Sbjct: 126 FVLERQLGRGSFGVVYCASAIHDSERKFAIKMQEKREIISKRAVLQVKREASIQRLLPSH 185 Query: 466 KSIVQLHEVMATRSKIYFVMEYMKG--GELFDKVSKAGKLTEGAAHKYFQQLISAVD 630 I + + TR+ +Y +++Y G G+LF + G L+E A +L SA+D Sbjct: 186 PFIARTYSTWQTRTHLYSLLQYPTGSTGDLFSVWRQRGSLSEAAIRLIGAELASAID 242
>KCC1G_HUMAN (Q96NX5) Calcium/calmodulin-dependent protein kinase type 1G (EC| 2.7.11.17) (CaM kinase IG) (CaM kinase I gamma) (CaMKI gamma) (CaMKI-gamma) (CaM-KI gamma) (CaMKIG) (CaMK-like CREB kinase III) (CLICK III) Length = 476 Score = 63.5 bits (153), Expect = 5e-10 Identities = 35/107 (32%), Positives = 58/107 (54%) Frame = +1 Query: 307 LLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHKSIVQLH 486 +LG GAF +V K + + A+K + K + E EI ++ + H++IV L Sbjct: 28 VLGSGAFSEVFLVKQRLTGKLFALKCIKKSPAFRDSSLEN---EIAVLKKIKHENIVTLE 84 Query: 487 EVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 ++ + + Y VM+ + GGELFD++ + G TE A QQ++SAV Sbjct: 85 DIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAV 131
>PLK2_MOUSE (P53351) Serine/threonine-protein kinase PLK2 (EC 2.7.11.21)| (Polo-like kinase 1) (PLK-2) (Serine/threonine-protein kinase SNK) (Serum-inducible kinase) Length = 682 Score = 63.2 bits (152), Expect = 6e-10 Identities = 34/113 (30%), Positives = 57/113 (50%) Frame = +1 Query: 289 RYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHK 468 RY G++LGKG F K + +L +N+ A K++ V K E++ +EI RL+ HK Sbjct: 78 RYCRGKVLGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVAKPHQREKIDKEIELHRLLHHK 137 Query: 469 SIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 +VQ + + IY ++EY + + LTE Y +Q++S + Sbjct: 138 HVVQFYHYFEDKENIYILLEYCSRRSMAHILKARKVLTEPEVRYYLRQIVSGL 190
>TSSK1_HUMAN (Q9BXA7) Testis-specific serine/threonine-protein kinase 1 (EC| 2.7.11.1) (TSSK-1) (Testis-specific kinase 1) (TSK-1) (Serine/threonine-protein kinase 22A) Length = 367 Score = 63.2 bits (152), Expect = 6e-10 Identities = 40/124 (32%), Positives = 66/124 (53%), Gaps = 1/124 (0%) Frame = +1 Query: 259 MENSGKIVMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRRE 438 M+++ + Y LG LG+G++ KV A + VAIK++D++ L + + RE Sbjct: 1 MDDAAVLKRRGYLLGINLGEGSYAKVKSAYSERLKFNVAIKIIDRKKAPADFLEKFLPRE 60 Query: 439 ITTMRLVAHKSIVQLHEVMAT-RSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQL 615 I + ++ H SI++ +E+ T K+Y VME G+L + + G L E A K F QL Sbjct: 61 IEILAMLNHCSIIKTYEIFETSHGKVYIVMELAVQGDLLELIKTRGALHEDEARKKFHQL 120 Query: 616 ISAV 627 A+ Sbjct: 121 SLAI 124
>KAPC_DROME (P12370) cAMP-dependent protein kinase catalytic subunit (EC| 2.7.11.11) (PKA C) Length = 352 Score = 62.8 bits (151), Expect = 8e-10 Identities = 32/113 (28%), Positives = 60/113 (53%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHKS 471 +E + LG G+FG+V ++ + A+K++DK+ V+K+ E E ++ + Sbjct: 45 FERIKTLGTGSFGRVMIVQHKPTKDYYAMKILDKQKVVKLKQVEHTLNEKRILQAIQFPF 104 Query: 472 IVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAVD 630 +V L S +Y V+EY+ GGE+F + K G+ +E + Y Q++ A + Sbjct: 105 LVSLRYHFKDNSNLYMVLEYVPGGEMFSHLRKVGRFSEPHSRFYAAQIVLAFE 157
>SGK1_MOUSE (Q9WVC6) Serine/threonine-protein kinase Sgk1 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 1) Length = 431 Score = 62.8 bits (151), Expect = 8e-10 Identities = 35/109 (32%), Positives = 60/109 (55%), Gaps = 1/109 (0%) Frame = +1 Query: 304 RLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTM-RLVAHKSIVQ 480 +++GKG+FGKV A++ A+K++ K+ +LK + + E + + V H +V Sbjct: 102 KVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLVG 161 Query: 481 LHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 LH T K+YFV++Y+ GGELF + + E A Y ++ SA+ Sbjct: 162 LHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASAL 210
>SGK1_HUMAN (O00141) Serine/threonine-protein kinase Sgk1 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 1) Length = 431 Score = 62.8 bits (151), Expect = 8e-10 Identities = 35/109 (32%), Positives = 60/109 (55%), Gaps = 1/109 (0%) Frame = +1 Query: 304 RLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTM-RLVAHKSIVQ 480 +++GKG+FGKV A++ A+K++ K+ +LK + + E + + V H +V Sbjct: 102 KVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLVG 161 Query: 481 LHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 LH T K+YFV++Y+ GGELF + + E A Y ++ SA+ Sbjct: 162 LHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASAL 210
>SGK3_MOUSE (Q9ERE3) Serine/threonine-protein kinase Sgk3 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 3) (Serum/glucocorticoid-regulated kinase-like) (Cytokine independent survival kinase) Length = 496 Score = 62.8 bits (151), Expect = 8e-10 Identities = 35/113 (30%), Positives = 61/113 (53%), Gaps = 1/113 (0%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTM-RLVAHK 468 ++ +++GKG+FGKV AK + A+K++ K+ VL + + E + + V H Sbjct: 162 FDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHP 221 Query: 469 SIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 +V LH T K+YFV++++ GGELF + + E A Y ++ SA+ Sbjct: 222 FLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEPRARFYAAEIASAL 274
>SGK3_HUMAN (Q96BR1) Serine/threonine-protein kinase Sgk3 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 3) (Serum/glucocorticoid-regulated kinase-like) Length = 496 Score = 62.8 bits (151), Expect = 8e-10 Identities = 35/113 (30%), Positives = 61/113 (53%), Gaps = 1/113 (0%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTM-RLVAHK 468 ++ +++GKG+FGKV AK + A+K++ K+ VL + + E + + V H Sbjct: 162 FDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHP 221 Query: 469 SIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 +V LH T K+YFV++++ GGELF + + E A Y ++ SA+ Sbjct: 222 FLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEHRARFYAAEIASAL 274
>KCC1_SCHPO (Q9P7I2) Calcium/calmodulin-dependent protein kinase type I (EC| 2.7.11.17) (CaMK-I) Length = 335 Score = 62.8 bits (151), Expect = 8e-10 Identities = 37/115 (32%), Positives = 63/115 (54%), Gaps = 2/115 (1%) Frame = +1 Query: 289 RYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVA-- 462 +Y +GR+LG G + V A ++E+N+ A K+M+K+ + K + V+ EI ++ V+ Sbjct: 30 KYRVGRVLGGGTYATVREAVHIETNKMYAAKIMNKKMMEKK--QDFVKNEIAILKRVSYE 87 Query: 463 HKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 H +I+ L + T + +Y + E GGELFD++ G E A + SAV Sbjct: 88 HPNILHLVDFFETVNNLYLITELATGGELFDRICAKGSFYEADAAALMRTTTSAV 142
>SGK2_HUMAN (Q9HBY8) Serine/threonine-protein kinase Sgk2 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 2) Length = 427 Score = 62.4 bits (150), Expect = 1e-09 Identities = 34/113 (30%), Positives = 61/113 (53%), Gaps = 1/113 (0%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTM-RLVAHK 468 ++ +++GKG +GKV AK A+K++ K+++LK + E + + + V H Sbjct: 95 FDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKNVRHP 154 Query: 469 SIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 +V L T K+YFV++Y+ GGELF + + + E A Y ++ SA+ Sbjct: 155 FLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAI 207
>PLK2_HUMAN (Q9NYY3) Serine/threonine-protein kinase PLK2 (EC 2.7.11.21)| (Polo-like kinase 1) (PLK-2) (Serine/threonine-protein kinase SNK) (Serum-inducible kinase) Length = 685 Score = 62.4 bits (150), Expect = 1e-09 Identities = 33/113 (29%), Positives = 57/113 (50%) Frame = +1 Query: 289 RYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHK 468 RY G++LGKG F K + +L +N+ A K++ V K E++ +EI R++ HK Sbjct: 81 RYCRGKVLGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVAKPHQREKIDKEIELHRILHHK 140 Query: 469 SIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 +VQ + + IY ++EY + + LTE Y +Q++S + Sbjct: 141 HVVQFYHYFEDKENIYILLEYCSRRSMAHILKARKVLTEPEVRYYLRQIVSGL 193
>KS6A5_HUMAN (O75582) Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1) (Nuclear| mitogen-and stress-activated protein kinase 1) (90 kDa ribosomal protein S6 kinase 5) (RSK-like protein kinase) (RSKL) Length = 802 Score = 62.4 bits (150), Expect = 1e-09 Identities = 39/142 (27%), Positives = 75/142 (52%), Gaps = 8/142 (5%) Frame = +1 Query: 229 LLAVTYTLEGMENSG---KIVMGRYELGRLLGKGAFGKVHYAKNL---ESNRGVAIKMMD 390 LL V + L +G K+ + +EL ++LG GA+GKV + + ++ + A+K++ Sbjct: 25 LLTVKHELRTANLTGHAEKVGIENFELLKVLGTGAYGKVFLVRKISGHDTGKLYAMKVLK 84 Query: 391 KETVL-KVGLAEQVRREITTMRLVAHKS-IVQLHEVMATRSKIYFVMEYMKGGELFDKVS 564 K T++ K E R E + + +V LH T +K++ +++Y+ GGELF +S Sbjct: 85 KATIVQKAKTTEHTRTERQVLEHIRQSPFLVTLHYAFQTETKLHLILDYINGGELFTHLS 144 Query: 565 KAGKLTEGAAHKYFQQLISAVD 630 + + TE Y +++ A++ Sbjct: 145 QRERFTEHEVQIYVGEIVLALE 166 Score = 62.0 bits (149), Expect = 1e-09 Identities = 35/107 (32%), Positives = 60/107 (56%), Gaps = 1/107 (0%) Frame = +1 Query: 310 LGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLV-AHKSIVQLH 486 LG+G+F + +SN+ A+K++ K + ++EIT ++L H +IV+LH Sbjct: 432 LGEGSFSICRKCVHKKSNQAFAVKIISKR------MEANTQKEITALKLCEGHPNIVKLH 485 Query: 487 EVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 EV + + VME + GGELF+++ K +E A ++L+SAV Sbjct: 486 EVFHDQLHTFLVMELLNGGELFERIKKKKHFSETEASYIMRKLVSAV 532
>DAPK1_HUMAN (P53355) Death-associated protein kinase 1 (EC 2.7.11.1) (DAP| kinase 1) Length = 1432 Score = 62.4 bits (150), Expect = 1e-09 Identities = 32/115 (27%), Positives = 63/115 (54%), Gaps = 3/115 (2%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVL--KVGLA-EQVRREITTMRLVA 462 Y+ G LG G F V + + A K + K + G++ E + RE++ ++ + Sbjct: 13 YDTGEELGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRGVSREDIEREVSILKEIQ 72 Query: 463 HKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 H +++ LHEV ++ + ++E + GGELFD +++ LTE A ++ +Q+++ V Sbjct: 73 HPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQILNGV 127
>KOK0_YEAST (Q12236) Probable serine/threonine-protein kinase YOL100W (EC| 2.7.11.1) Length = 1081 Score = 62.4 bits (150), Expect = 1e-09 Identities = 32/114 (28%), Positives = 62/114 (54%), Gaps = 1/114 (0%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHK- 468 ++ G ++G GA+ V A ++++ + A K+++KE +++ + V E T ++ + + Sbjct: 179 FKFGSVIGDGAYSTVMLATSIDTKKRYAAKVLNKEYLIRQKKVKYVSIEKTALQKLNNSP 238 Query: 469 SIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAVD 630 S+V+L S +YF++EY G+ + K G L E A Y Q+I A+D Sbjct: 239 SVVRLFSTFQDESSLYFLLEYAPNGDFLSLMKKYGSLDETCARYYAAQIIDAID 292
>KS6A5_MOUSE (Q8C050) Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1) (Nuclear| mitogen-and stress-activated protein kinase 1) (90 kDa ribosomal protein S6 kinase 5) (RSK-like protein kinase) (RLSK) Length = 863 Score = 62.4 bits (150), Expect = 1e-09 Identities = 39/142 (27%), Positives = 75/142 (52%), Gaps = 8/142 (5%) Frame = +1 Query: 229 LLAVTYTLEGMENSG---KIVMGRYELGRLLGKGAFGKVHYAKNL---ESNRGVAIKMMD 390 LL V + L +G K+ + +EL ++LG GA+GKV + + ++ + A+K++ Sbjct: 24 LLTVKHELRTANLTGHAEKVGIENFELLKVLGTGAYGKVFLVRKISGHDAGKLYAMKVLK 83 Query: 391 KETVL-KVGLAEQVRREITTMRLVAHKS-IVQLHEVMATRSKIYFVMEYMKGGELFDKVS 564 K T++ K E R E + + +V LH T +K++ +++Y+ GGELF +S Sbjct: 84 KATIVQKAKTTEHTRTERQVLEHIRQSPFLVTLHYAFQTETKLHLILDYINGGELFTHLS 143 Query: 565 KAGKLTEGAAHKYFQQLISAVD 630 + + TE Y +++ A++ Sbjct: 144 QRERFTEHEVQIYVGEIVLALE 165 Score = 33.5 bits (75), Expect = 0.53 Identities = 19/62 (30%), Positives = 35/62 (56%), Gaps = 1/62 (1%) Frame = +1 Query: 310 LGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLV-AHKSIVQLH 486 LG+G+F + ++N+ A+K++ K + ++EIT ++L H +IV+LH Sbjct: 431 LGEGSFSICRKCVHKKTNQAFAVKIISKR------MEANTQKEITALKLCEGHPNIVKLH 484 Query: 487 EV 492 EV Sbjct: 485 EV 486 Score = 33.1 bits (74), Expect = 0.70 Identities = 14/38 (36%), Positives = 24/38 (63%) Frame = +1 Query: 514 YFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 + VME + GGELF+++ + +E A ++L+SAV Sbjct: 559 FLVMELLNGGELFERIKRKKHFSETEASYIMRKLVSAV 596
>M3K2_HUMAN (Q9Y2U5) Mitogen-activated protein kinase kinase kinase 2 (EC| 2.7.11.25) (MAPK/ERK kinase kinase 2) (MEK kinase 2) (MEKK 2) Length = 619 Score = 62.4 bits (150), Expect = 1e-09 Identities = 38/119 (31%), Positives = 65/119 (54%), Gaps = 7/119 (5%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMD-----KETVLKVGLAEQVRREITTMRL 456 + LG+LLG+GAFG+V+ ++++ R +A+K + ET +V E EI ++ Sbjct: 356 WRLGKLLGQGAFGRVYLCYDVDTGRELAVKQVQFDPDSPETSKEVNALEC---EIQLLKN 412 Query: 457 VAHKSIVQLHEVMATRSK--IYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 + H+ IVQ + + + + MEYM GG + D++ G LTE KY +Q++ V Sbjct: 413 LLHERIVQYYGCLRDPQEKTLSIFMEYMPGGSIKDQLKAYGALTENVTRKYTRQILEGV 471
>PLK2_RAT (Q9R012) Serine/threonine-protein kinase PLK2 (EC 2.7.11.21)| (Polo-like kinase 1) (PLK-2) (Serine/threonine-protein kinase SNK) (Serum-inducible kinase) Length = 682 Score = 62.4 bits (150), Expect = 1e-09 Identities = 33/113 (29%), Positives = 57/113 (50%) Frame = +1 Query: 289 RYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHK 468 RY G++LGKG F K + +L +N+ A K++ V K E++ +EI R++ HK Sbjct: 78 RYCRGKVLGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVAKPHQREKIDKEIELHRILHHK 137 Query: 469 SIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 +VQ + + IY ++EY + + LTE Y +Q++S + Sbjct: 138 HVVQFYHYFEDKENIYILLEYCSRRSMAHILKARKVLTEPEVRYYLRQIVSGL 190
>KS6A5_PONPY (Q5R4K3) Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1)| Length = 802 Score = 62.0 bits (149), Expect = 1e-09 Identities = 35/107 (32%), Positives = 60/107 (56%), Gaps = 1/107 (0%) Frame = +1 Query: 310 LGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLV-AHKSIVQLH 486 LG+G+F + +SN+ A+K++ K + ++EIT ++L H +IV+LH Sbjct: 432 LGEGSFSICRKCVHKKSNQAFAVKIISKR------MEANTQKEITALKLCEGHPNIVKLH 485 Query: 487 EVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 EV + + VME + GGELF+++ K +E A ++L+SAV Sbjct: 486 EVFHDQLHTFLVMELLNGGELFERIKKKKHFSETEASYIMRKLVSAV 532 Score = 60.1 bits (144), Expect = 5e-09 Identities = 38/142 (26%), Positives = 74/142 (52%), Gaps = 8/142 (5%) Frame = +1 Query: 229 LLAVTYTLEGMENSG---KIVMGRYELGRLLGKGAFGKVHYAKNL---ESNRGVAIKMMD 390 LL V + L +G ++ + +EL ++LG GA+GKV + + ++ + A+K++ Sbjct: 25 LLTVKHELRTANLTGHAERVGIENFELLKVLGTGAYGKVFLVRKISGHDTGKLYAMKVLK 84 Query: 391 KETVL-KVGLAEQVRREITTMRLVAHKS-IVQLHEVMATRSKIYFVMEYMKGGELFDKVS 564 K T++ K E R E + +V LH T +K++ +++Y+ GGELF +S Sbjct: 85 KATIVQKAKTTEHTRTERQVLEHTRQSPFLVTLHYAFQTETKLHLILDYINGGELFTHLS 144 Query: 565 KAGKLTEGAAHKYFQQLISAVD 630 + + TE Y +++ A++ Sbjct: 145 QRERFTEHEVQIYVGEIVLALE 166
>KAPC_CAEEL (P21137) cAMP-dependent protein kinase catalytic subunit (EC| 2.7.11.11) (PKA C) Length = 404 Score = 62.0 bits (149), Expect = 1e-09 Identities = 30/109 (27%), Positives = 59/109 (54%) Frame = +1 Query: 304 RLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHKSIVQL 483 + LG G+FG+V K+ +S A+K++DK+ V+K+ E E ++ + +V + Sbjct: 85 KTLGTGSFGRVMLVKHKQSGNYYAMKILDKQKVVKLKQVEHTLNEKRILQAIDFPFLVNM 144 Query: 484 HEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAVD 630 S +Y V+E++ GGE+F + + G+ +E + Y Q++ A + Sbjct: 145 TFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFE 193
>KS6A4_MOUSE (Q9Z2B9) Ribosomal protein S6 kinase alpha-4 (EC 2.7.11.1) (Nuclear| mitogen-and stress-activated protein kinase 2) (90 kDa ribosomal protein S6 kinase 4) (RSK-like protein kinase) (RLSK) Length = 773 Score = 62.0 bits (149), Expect = 1e-09 Identities = 33/107 (30%), Positives = 59/107 (55%), Gaps = 1/107 (0%) Frame = +1 Query: 310 LGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLV-AHKSIVQLH 486 LG+G+F + +S + A+K++ + L E +RE+ +RL +H ++V LH Sbjct: 417 LGQGSFSVCRRCRQRQSGQEFAVKILSRR------LEENTQREVAALRLCQSHPNVVNLH 470 Query: 487 EVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 EV+ + Y V+E ++GGEL + + K +E A + + L+SAV Sbjct: 471 EVLHDQLHTYLVLELLRGGELLEHIRKKRLFSESEASQILRSLVSAV 517 Score = 49.7 bits (117), Expect = 7e-06 Identities = 30/124 (24%), Positives = 64/124 (51%), Gaps = 5/124 (4%) Frame = +1 Query: 274 KIVMGRYELGRLLGKGAFGKVHYAKNL---ESNRGVAIKMMDKETVL-KVGLAEQVRREI 441 K+ + + L ++LG GA+GKV + ++ + A+K++ K ++ + E R E Sbjct: 27 KVSVENFALLKVLGTGAYGKVFLVRKTGGHDAGKLYAMKVLRKAALVQRAKTQEHTRTER 86 Query: 442 TTMRLVAHKS-IVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLI 618 + + LV +V LH T +K++ +++Y+ GGE+F + + E Y +++ Sbjct: 87 SVLELVRQAPFLVTLHYAFQTDAKLHLILDYVSGGEMFTHLYQRQYFKEAEVRVYGGEIV 146 Query: 619 SAVD 630 A++ Sbjct: 147 LALE 150
>SGK2_MOUSE (Q9QZS5) Serine/threonine-protein kinase Sgk2 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 2) Length = 367 Score = 61.6 bits (148), Expect = 2e-09 Identities = 34/113 (30%), Positives = 60/113 (53%), Gaps = 1/113 (0%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTM-RLVAHK 468 ++ +++GKG +GKV AK A+K++ K+++LK + E + + V H Sbjct: 35 FDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKNKEQNHIMAERNVLLKNVRHP 94 Query: 469 SIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 +V L T K+YFV++Y+ GGELF + + + E A Y ++ SA+ Sbjct: 95 FLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYTAEVASAI 147
>AKT1_CAEEL (Q17941) Serine/threonine-protein kinase akt-1 (EC 2.7.11.1)| (Protein kinase B akt-1) (PKB akt-1) Length = 541 Score = 61.6 bits (148), Expect = 2e-09 Identities = 39/136 (28%), Positives = 70/136 (51%), Gaps = 3/136 (2%) Frame = +1 Query: 229 LLAVTYTLEGMENSGKIVMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLK 408 ++++ T E + KI M ++ ++LGKG FGKV K + + AIK++ K+ ++ Sbjct: 173 MISIADTSEAAKRD-KITMEDFDFLKVLGKGTFGKVILCKEKRTQKLYAIKILKKDVII- 230 Query: 409 VGLAEQVRREITTMRLV---AHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKL 579 E+V +T R++ H + +L + + FVM++ GGELF V K G Sbjct: 231 --AREEVAHTLTENRVLQRCKHPFLTELKYSFQEQHYLCFVMQFANGGELFTHVRKCGTF 288 Query: 580 TEGAAHKYFQQLISAV 627 +E A Y +++ A+ Sbjct: 289 SEPRARFYGAEIVLAL 304
>SGK2_RAT (Q8R4U9) Serine/threonine-protein kinase Sgk2 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 2) (Fragment) Length = 302 Score = 61.6 bits (148), Expect = 2e-09 Identities = 34/113 (30%), Positives = 60/113 (53%), Gaps = 1/113 (0%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTM-RLVAHK 468 ++ +++GKG +GKV AK A+K++ K+++LK + E + + V H Sbjct: 18 FDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKNKEQSHIMAERNVLLKNVRHP 77 Query: 469 SIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 +V L T K+YFV++Y+ GGELF + + + E A Y ++ SA+ Sbjct: 78 FLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQREHRFLEPRARFYTAEVASAI 130
>KPC1_CANAL (P43057) Protein kinase C-like 1 (EC 2.7.11.13) (PKC 1)| Length = 1097 Score = 61.6 bits (148), Expect = 2e-09 Identities = 34/101 (33%), Positives = 58/101 (57%), Gaps = 3/101 (2%) Frame = +1 Query: 274 KIVMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRRE---IT 444 K+ + ++ +LGKG FGKV A++ +++ AIK++ K+ +++ AE V+ E Sbjct: 764 KVGLDDFQFLAVLGKGNFGKVMLAESRHTSKLCAIKVLKKDFIVENDEAESVKSEKRVFL 823 Query: 445 TMRLVAHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSK 567 T H ++ LH T ++IYFVMEY+ GG+L + K Sbjct: 824 TANKEMHPFLLNLHCCFQTENRIYFVMEYISGGDLMWHIQK 864
>KS6A6_HUMAN (Q9UK32) Ribosomal protein S6 kinase alpha-6 (EC 2.7.11.1)| (S6K-alpha 6) (90 kDa ribosomal protein S6 kinase 6) (p90-RSK 6) (Ribosomal S6 kinase 4) (RSK-4) (pp90RSK4) Length = 745 Score = 61.2 bits (147), Expect = 2e-09 Identities = 36/117 (30%), Positives = 67/117 (57%), Gaps = 3/117 (2%) Frame = +1 Query: 289 RYELGRLLGKGAFGKVHYAKNL---ESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLV 459 ++EL ++LG+G+FGKV + ++ + A+K++ K + LKV + + E + V Sbjct: 72 QFELLKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLKKAS-LKVRDRVRTKMERDILVEV 130 Query: 460 AHKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAVD 630 H IV+LH T K+Y ++++++GG++F ++SK TE Y +L A+D Sbjct: 131 NHPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRLSKEVLFTEEDVKFYLAELALALD 187 Score = 45.8 bits (107), Expect = 1e-04 Identities = 32/113 (28%), Positives = 52/113 (46%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHKS 471 YEL +G G++ + +N A+K++DK K +E++ MR H + Sbjct: 426 YELKEDIGVGSYSVCKRCIHATTNMEFAVKIIDKS---KRDPSEEIE---ILMRYGQHPN 479 Query: 472 IVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAVD 630 I+ L +V +Y V + MKGGEL D++ K +E A + VD Sbjct: 480 IITLKDVFDDGRYVYLVTDLMKGGELLDRILKQKCFSEREASDILYVISKTVD 532
>CDPK3_PLAF7 (Q9NJU9) Calcium-dependent protein kinase 3 (EC 2.7.11.1) (PfCDPK3)| Length = 562 Score = 61.2 bits (147), Expect = 2e-09 Identities = 36/107 (33%), Positives = 59/107 (55%) Frame = +1 Query: 310 LGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHKSIVQLHE 489 LGKG +G V+ A + A+K++ K+ + + + R+EI M+ + H ++V+L E Sbjct: 124 LGKGTYGCVYKATDKLLKISRAVKVVSKKKLKNI---PRFRQEIDIMKNLDHPNVVKLLE 180 Query: 490 VMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAVD 630 ++IY VME GGELFDK+ K G E A +Q+ S ++ Sbjct: 181 TFEDSNQIYLVMELCTGGELFDKIVKKGCFVETFASFIMKQIFSVLN 227
>KPC3_DROME (P13678) Protein kinase C (EC 2.7.11.13) (PKC) (dPKC98F)| Length = 634 Score = 61.2 bits (147), Expect = 2e-09 Identities = 36/125 (28%), Positives = 64/125 (51%), Gaps = 1/125 (0%) Frame = +1 Query: 256 GMENSGKIVMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRR 435 G GK + + ++LGKG+FGKV A+ ++ AIK++ K+ +++ + Sbjct: 291 GETRPGKCSLLDFNFIKVLGKGSFGKVMLAEKKGTDEIYAIKVLKKDAIIQDDDVDCTMT 350 Query: 436 EITTMRLVA-HKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQ 612 E + L A H + LH T +++FVMEY+ GG+L ++ KA + A Y + Sbjct: 351 EKRILALAANHPFLTALHSCFQTPDRLFFVMEYVNGGDLMFQIQKARRFEASRAAFYAAE 410 Query: 613 LISAV 627 + A+ Sbjct: 411 VTLAL 415
>KCC2_SCHPO (O42844) Calcium/calmodulin-dependent protein kinase type II (EC| 2.7.11.17) (CAM kinase II) Length = 504 Score = 61.2 bits (147), Expect = 2e-09 Identities = 37/113 (32%), Positives = 61/113 (53%) Frame = +1 Query: 289 RYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHK 468 +Y+L LG GAF +V+ A +++ VA+K++ K + K + V +E+ MR V HK Sbjct: 64 KYQLIENLGDGAFSQVYKAYSIDRKEHVAVKVIRKYEMNKKQ-RQGVFKEVNIMRRVKHK 122 Query: 469 SIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 ++V L + + T + VME +GGELF ++ +E A Q+ AV Sbjct: 123 NVVNLFDFVETEDFYHLVMELAEGGELFHQIVNFTYFSENLARHIIIQVAEAV 175
>KPC1_APLCA (Q16974) Calcium-dependent protein kinase C (EC 2.7.11.13) (APL I)| Length = 649 Score = 61.2 bits (147), Expect = 2e-09 Identities = 35/104 (33%), Positives = 57/104 (54%), Gaps = 1/104 (0%) Frame = +1 Query: 307 LLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHKS-IVQL 483 +LGKG+FGKV A+ ++ AIK++ K+ +++ E E + L +VQL Sbjct: 325 VLGKGSFGKVVLAERKGTDELYAIKILKKDVIIQDDDVECTMIEKRVLALPDKPPFLVQL 384 Query: 484 HEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQL 615 H T ++YFVMEY+ GG+L ++ + GK E A Y ++ Sbjct: 385 HSCFQTMDRLYFVMEYVNGGDLMYRIQQEGKFKEPVAAFYAAEI 428
>KCC4_MOUSE (P08414) Calcium/calmodulin-dependent protein kinase type IV (EC| 2.7.11.17) (CAM kinase-GR) (CaMK IV) Length = 469 Score = 60.8 bits (146), Expect = 3e-09 Identities = 35/112 (31%), Positives = 63/112 (56%) Frame = +1 Query: 292 YELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMRLVAHKS 471 +E+ LG+GA V+ K + + A+K++ K K+ VR EI + ++H + Sbjct: 42 FEVESELGRGATSIVYRCKQKGTQKPYALKVLKKTVDKKI-----VRTEIGVLLRLSHPN 96 Query: 472 IVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLISAV 627 I++L E+ T ++I V+E + GGELFD++ + G +E A +Q++ AV Sbjct: 97 IIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDARDAVKQILEAV 148
>KPCE_RABIT (P10830) Protein kinase C epsilon type (EC 2.7.11.13)| (nPKC-epsilon) Length = 736 Score = 60.8 bits (146), Expect = 3e-09 Identities = 34/122 (27%), Positives = 69/122 (56%), Gaps = 4/122 (3%) Frame = +1 Query: 274 KIVMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMR 453 ++ + + ++LGKG+FGKV A+ + A+K++ K+ +L+ + V +T R Sbjct: 401 RLGLDEFNFIKVLGKGSFGKVMLAELKGKDEVYAVKVLKKDVILQ---DDDVDCTMTEKR 457 Query: 454 LVA----HKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLIS 621 ++A H + QL+ T+ +++FVMEY+ GG+L ++ ++ K E + Y ++ S Sbjct: 458 ILALARKHPYLTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTS 517 Query: 622 AV 627 A+ Sbjct: 518 AL 519
>STK11_XENLA (Q91604) Serine/threonine-protein kinase 11 (EC 2.7.11.1)| (Serine/threonine-protein kinase XEEK1) (Egg and embryo kinase 1) Length = 432 Score = 60.8 bits (146), Expect = 3e-09 Identities = 39/122 (31%), Positives = 71/122 (58%), Gaps = 5/122 (4%) Frame = +1 Query: 280 VMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAE-QVRREITTMRL 456 ++G+Y +G LLG+G++GKV + ++ A+K++ K+ + ++ E V++EI +R Sbjct: 48 LVGKYLMGDLLGEGSYGKVKEMLDSDTLCRRAVKILKKKKLRRIPNGEANVKKEIQLLRR 107 Query: 457 VAHKSIVQLHEVM--ATRSKIYFVMEYMKGG--ELFDKVSKAGKLTEGAAHKYFQQLISA 624 + H++++QL +V+ + K+Y VMEY G E+ D V AH YF QLI Sbjct: 108 LRHRNVIQLVDVLYNEEKQKMYMVMEYCVCGMQEMLDSVQDK-HFPVFQAHGYFCQLIDG 166 Query: 625 VD 630 ++ Sbjct: 167 LE 168
>KPCE_MOUSE (P16054) Protein kinase C epsilon type (EC 2.7.11.13)| (nPKC-epsilon) Length = 737 Score = 60.8 bits (146), Expect = 3e-09 Identities = 34/122 (27%), Positives = 69/122 (56%), Gaps = 4/122 (3%) Frame = +1 Query: 274 KIVMGRYELGRLLGKGAFGKVHYAKNLESNRGVAIKMMDKETVLKVGLAEQVRREITTMR 453 ++ + + ++LGKG+FGKV A+ + A+K++ K+ +L+ + V +T R Sbjct: 402 RLGLDEFNFIKVLGKGSFGKVMLAELKGKDEVYAVKVLKKDVILQ---DDDVDCTMTEKR 458 Query: 454 LVA----HKSIVQLHEVMATRSKIYFVMEYMKGGELFDKVSKAGKLTEGAAHKYFQQLIS 621 ++A H + QL+ T+ +++FVMEY+ GG+L ++ ++ K E + Y ++ S Sbjct: 459 ILALARKHPYLTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTS 518 Query: 622 AV 627 A+ Sbjct: 519 AL 520 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 96,677,167 Number of Sequences: 219361 Number of extensions: 2072650 Number of successful extensions: 7421 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 6596 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 6906 length of database: 80,573,946 effective HSP length: 107 effective length of database: 57,102,319 effective search space used: 5824436538 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
