ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | basd2a12 |
|---|---|
| Clone Library Name | barley_pub |
>DHGY_CUCSA (P13443) Glycerate dehydrogenase (EC 1.1.1.29) (NADH-dependent| hydroxypyruvate reductase) (HPR) (GDH) Length = 382 Score = 343 bits (880), Expect = 2e-94 Identities = 166/189 (87%), Positives = 181/189 (95%) Frame = +2 Query: 2 PHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFL 181 P+LFVGNLLKGQTVGVIGAGRIGSAYARMM+EGFKMNLIYFDLYQSTRLEKFVTAYG+FL Sbjct: 155 PNLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGEFL 214 Query: 182 KANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRG 361 KANGE PVTW+RASSM+EVLREADVISLHPVLDKTT+HL+N E L MKK+A+L+N SRG Sbjct: 215 KANGEAPVTWRRASSMDEVLREADVISLHPVLDKTTFHLVNKESLKAMKKDAILINCSRG 274 Query: 362 PVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMAT 541 PVIDE ALV+HL+ NPMFRVGLDVFEDEPYMKPGLA+MKNA++VPHIASASKWTREGMAT Sbjct: 275 PVIDEAALVDHLRDNPMFRVGLDVFEDEPYMKPGLADMKNAIIVPHIASASKWTREGMAT 334 Query: 542 LAALNVLGK 568 LAALNVLGK Sbjct: 335 LAALNVLGK 343
>GYAR_THELI (Q9C4M5) Glyoxylate reductase (EC 1.1.1.26) (Glycolate reductase)| Length = 331 Score = 136 bits (343), Expect = 4e-32 Identities = 79/188 (42%), Positives = 111/188 (59%), Gaps = 1/188 (0%) Frame = +2 Query: 2 PHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTA-YGQF 178 P +F+G LKG+T+G++G GRIG A A+ +GF M +IY+ + E+ + A Y F Sbjct: 140 PLMFLGYGLKGKTLGIVGFGRIGQALAKRA-KGFGMKIIYYSRTRKPEAEEEIGAEYVDF 198 Query: 179 LKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASR 358 E +L+E+D ISLH L K TYH+I + L +MK A+L+N SR Sbjct: 199 -----------------ETLLKESDFISLHVPLTKETYHMIGEKELKLMKPNAILINTSR 241 Query: 359 GPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 538 G V+D AL++ LK + GLDVFE+EPY L ++KN V+ PHI SA+ REGMA Sbjct: 242 GAVVDTNALIKALKEGWIAGAGLDVFEEEPYYNEELFKLKNVVLAPHIGSATHEAREGMA 301 Query: 539 TLAALNVL 562 L A N++ Sbjct: 302 ELVAKNLI 309
>GYAR_PYRHO (O58320) Glyoxylate reductase (EC 1.1.1.26) (Glycolate reductase)| Length = 334 Score = 135 bits (341), Expect = 6e-32 Identities = 77/187 (41%), Positives = 110/187 (58%) Frame = +2 Query: 2 PHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFL 181 P F+G + G+T+G+IG GRIG A A+ +GF M ++Y+ + +E+ + A Sbjct: 140 PKWFLGYDVYGKTIGIIGLGRIGQAIAKRA-KGFNMRILYYSRTRKEEVERELNA----- 193 Query: 182 KANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRG 361 +E++LRE+D + L L + TYHLIN ERL +MKK A+L+N +RG Sbjct: 194 -----------EFKPLEDLLRESDFVVLAVPLTRETYHLINEERLKLMKKTAILINIARG 242 Query: 362 PVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMAT 541 V+D ALV+ LK + GLDVFE+EPY L ++ N V+ PHI SAS REGMA Sbjct: 243 KVVDTNALVKALKEGWIAGAGLDVFEEEPYYNEELFKLDNVVLTPHIGSASFGAREGMAE 302 Query: 542 LAALNVL 562 L A N++ Sbjct: 303 LVAKNLI 309
>GYAR_PYRAB (Q9UYR1) Glyoxylate reductase (EC 1.1.1.26) (Glycolate reductase)| Length = 335 Score = 134 bits (338), Expect = 1e-31 Identities = 76/187 (40%), Positives = 109/187 (58%) Frame = +2 Query: 2 PHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFL 181 P F+G + G+T+G+IG GRIG A A+ GF M ++Y+ + +EK + A Sbjct: 141 PKWFLGYDVYGKTIGIIGFGRIGQAIAKRA-RGFDMRILYYSRTRKPEVEKELNA----- 194 Query: 182 KANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRG 361 ++E+LRE+D + L L+K TYH+IN ERL MMK+ A+L+N +RG Sbjct: 195 -----------EFKPLDELLRESDFVVLAVPLNKETYHMINEERLKMMKRTAILINVARG 243 Query: 362 PVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMAT 541 VID AL++ LK + GLDV+E+EPY L + N V+ PHI SA+ REGMA Sbjct: 244 KVIDTKALIKALKEGWIAGAGLDVYEEEPYYNEELFSLDNVVLTPHIGSATFGAREGMAK 303 Query: 542 LAALNVL 562 L A N++ Sbjct: 304 LVAENLI 310
>GYAR_PYRKO (Q5JEZ2) Glyoxylate reductase (EC 1.1.1.26) (Glycolate reductase)| Length = 333 Score = 131 bits (329), Expect = 2e-30 Identities = 76/187 (40%), Positives = 108/187 (57%) Frame = +2 Query: 2 PHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFL 181 P F+G + G+T+G++G GRIG A AR GF M ++Y+ + EK + A Sbjct: 140 PRWFLGYDVYGKTIGIVGFGRIGQAVARRA-RGFGMRILYYSRSRKPEAEKELGA----- 193 Query: 182 KANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRG 361 S+E++LRE+D + L L K T ++IN ERL +MKK A+LVN +RG Sbjct: 194 -----------EFRSLEDLLRESDFVVLAVPLTKETQYMINEERLRLMKKTAILVNIARG 242 Query: 362 PVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMAT 541 V+D AL++ LK + GLDV+E+EPY L +KN V+ PHI SA+ REGMA Sbjct: 243 KVVDTKALMKALKEGWIAGAGLDVYEEEPYYNEELFSLKNVVLAPHIGSATYGAREGMAE 302 Query: 542 LAALNVL 562 L A N++ Sbjct: 303 LVARNLI 309
>GYAR_PYRFU (Q8U3Y2) Glyoxylate reductase (EC 1.1.1.26) (Glycolate reductase)| Length = 336 Score = 128 bits (321), Expect = 1e-29 Identities = 75/187 (40%), Positives = 107/187 (57%) Frame = +2 Query: 2 PHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFL 181 P F+G L G+T+G++G GRIG A AR +GF M ++Y+ + ++ EK + A Sbjct: 140 PKWFLGYELYGKTIGIVGFGRIGQAIARRA-KGFNMRILYYSRTRKSQAEKELGA----- 193 Query: 182 KANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRG 361 +EEVL+E+D + L L K T ++IN ERL +MK A+LVN +RG Sbjct: 194 -----------EYRPLEEVLKESDFVILAVPLTKETMYMINEERLKLMKPTAILVNIARG 242 Query: 362 PVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMAT 541 V+D AL++ LK + GLDVFE+EPY L + N V+ PHI SA+ RE MA Sbjct: 243 KVVDTKALIKALKEGWIAGAGLDVFEEEPYYNEELFSLDNVVLTPHIGSATFEAREAMAE 302 Query: 542 LAALNVL 562 L A N++ Sbjct: 303 LVARNLI 309
>GYAR_AERPE (Q9YAW4) Glyoxylate reductase (EC 1.1.1.26) (Glycolate reductase)| Length = 335 Score = 115 bits (288), Expect = 9e-26 Identities = 72/189 (38%), Positives = 107/189 (56%), Gaps = 2/189 (1%) Frame = +2 Query: 2 PHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFL 181 P + +G L+G+T+G++G GRIGS A + + F M +IY + +EK + A Sbjct: 141 PMMMLGVELRGKTLGILGMGRIGSRVAEIG-KAFGMRIIYHSRSRKREIEKELGA----- 194 Query: 182 KANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRG 361 S+E++LRE+D++S+H L T HLI L +MKK A+LVN RG Sbjct: 195 -----------EYRSLEDLLRESDILSIHLPLTDETRHLIGESELKLMKKTAILVNTGRG 243 Query: 362 PVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPG--LAEMKNAVVVPHIASASKWTREGM 535 ++D ALV+ L+ + LDVFE+EP + P L KN V+ PH ASA++ TR M Sbjct: 244 AIVDTGALVKALREGWIAAAALDVFEEEP-LNPNHPLTAFKNVVLAPHAASATRETRLRM 302 Query: 536 ATLAALNVL 562 A +AA N++ Sbjct: 303 AMMAAENLV 311
>TKRA_ECOLI (P37666) 2-ketogluconate reductase (EC 1.1.1.215) (2KR)| (2-ketoaldonate reductase) Length = 324 Score = 105 bits (261), Expect = 1e-22 Identities = 65/177 (36%), Positives = 91/177 (51%), Gaps = 1/177 (0%) Frame = +2 Query: 35 QTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWK 214 +T+G++G GRIG A A+ GF M ++Y E+ A Sbjct: 146 KTLGIVGMGRIGMALAQRAHFGFNMPILYNARRHHKEAEERFNA---------------- 189 Query: 215 RASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEH 394 R ++ +L+E+D + L L T+HL E+ A MK A+ +NA RGPV+DE AL+ Sbjct: 190 RYCDLDTLLQESDFVCLILPLTDETHHLFGAEQFAKMKSSAIFINAGRGPVVDENALIAA 249 Query: 395 LKANPMFRVGLDVFEDEPY-MKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVL 562 L+ + GLDVFE EP + L M N V VPHI SA+ TR GMA A N++ Sbjct: 250 LQKGEIHAAGLDVFEQEPLSVDSPLLSMANVVAVPHIGSATHETRYGMAACAVDNLI 306
>TKRA_ECO57 (P58220) 2-ketogluconate reductase (EC 1.1.1.215) (2KR)| (2-ketoaldonate reductase) Length = 324 Score = 105 bits (261), Expect = 1e-22 Identities = 65/177 (36%), Positives = 91/177 (51%), Gaps = 1/177 (0%) Frame = +2 Query: 35 QTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWK 214 +T+G++G GRIG A A+ GF M ++Y E+ A Sbjct: 146 KTLGIVGMGRIGMALAQRAHFGFNMPILYNARRHHKEAEERFNA---------------- 189 Query: 215 RASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEH 394 R ++ +L+E+D + L L T+HL E+ A MK A+ +NA RGPV+DE AL+ Sbjct: 190 RYCDLDTLLQESDFVCLILPLTDETHHLFGAEQFAKMKSSAIFINAGRGPVVDENALIAA 249 Query: 395 LKANPMFRVGLDVFEDEPY-MKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVL 562 L+ + GLDVFE EP + L M N V VPHI SA+ TR GMA A N++ Sbjct: 250 LQKGEIHAAGLDVFEQEPLSVDSPLLSMANVVAVPHIGSATHETRYGMAACAVDNLI 306
>TKRA_ENTAG (P58000) 2-ketogluconate reductase (EC 1.1.1.215) (2KR)| (2-ketoaldonate reductase) Length = 323 Score = 102 bits (255), Expect = 6e-22 Identities = 64/175 (36%), Positives = 92/175 (52%), Gaps = 1/175 (0%) Frame = +2 Query: 41 VGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRA 220 +G++G GRIG A A+ GF M ++Y E A + Sbjct: 147 MGILGMGRIGLALAQRAHHGFGMPILYNARKHHEEAESRFNA----------------QY 190 Query: 221 SSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLK 400 ++ +LRE+D + + L + T+H+I E+LA MK A+L+NA RGPV+DE AL+ LK Sbjct: 191 CDLDTLLRESDFLCISLPLTEQTHHMIGREQLAKMKPSAILINAGRGPVVDEQALIAALK 250 Query: 401 ANPMFRVGLDVFEDEPY-MKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVL 562 + GLDVFE EP + L + N V +PHI SA+ TR GMA A N++ Sbjct: 251 DKTIHAAGLDVFEQEPLPVDSELLTLPNVVALPHIGSATHETRYGMARDAVDNLI 305
>SERA_METTH (O27051) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 525 Score = 101 bits (252), Expect = 1e-21 Identities = 63/180 (35%), Positives = 98/180 (54%) Frame = +2 Query: 11 FVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKAN 190 F+G L G+T+G+IG GRIGS + + F M+++ +D Y S +A Sbjct: 134 FMGIELNGKTLGIIGMGRIGSQVV-VRTKAFGMDIMVYDPYISK-------------EAA 179 Query: 191 GEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVI 370 E VT + +E +LRE+D++++H L T HLI+ + +MK A +VN +RG +I Sbjct: 180 EEMGVT---VTDLETLLRESDIVTIHVPLTPETRHLISEDEFKLMKDTAFIVNCARGGII 236 Query: 371 DEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAA 550 DE AL LK + LDVFE+EP L E++N V+ PHI +++ + A + A Sbjct: 237 DEDALYRALKDGEIAGAALDVFEEEPPEGSPLLELENVVLTPHIGASTSEAQRDAAIIVA 296
>SERA_METJA (Q58424) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 524 Score = 96.7 bits (239), Expect = 4e-20 Identities = 60/180 (33%), Positives = 93/180 (51%) Frame = +2 Query: 11 FVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKAN 190 F G L G+T+GVIG GRIG + + F MN+I +D Y + + + Sbjct: 132 FKGIELYGKTLGVIGLGRIGQQVVKRA-KAFGMNIIGYDPYIPKEVAESMGV-------- 182 Query: 191 GEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVI 370 + + E+ + AD I+LH L T H+I E++A+MKK A++VN +RG +I Sbjct: 183 -------ELVDDINELCKRADFITLHVPLTPKTRHIIGREQIALMKKNAIIVNCARGGLI 235 Query: 371 DEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAA 550 DE AL E LK + LDVFE+EP L + N + PH ++++ ++ T+ A Sbjct: 236 DEKALYEALKEGKIRAAALDVFEEEPPKDNPLLTLDNVIGTPHQGASTEEAQKAAGTIVA 295
>YEAA_SCHPO (O14075) Putative 2-hydroxyacid dehydrogenase UNK4.10 (EC 1.-.-.-)| Length = 334 Score = 96.3 bits (238), Expect = 5e-20 Identities = 58/177 (32%), Positives = 95/177 (53%) Frame = +2 Query: 29 KGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVT 208 +G+T+G++G G IG A+ F M ++Y + T L + +F+ Sbjct: 155 EGKTLGILGLGGIGKTMAKRA-RAFDMKIVY---HNRTPLPEEEAEGAEFV--------- 201 Query: 209 WKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALV 388 S +++L ++DV+SL+ L+ T H+I MK+ V+VN +RG V+DE ALV Sbjct: 202 -----SFDDLLAKSDVLSLNLPLNAHTRHIIGKPEFQKMKRGIVIVNTARGAVMDEAALV 256 Query: 389 EHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNV 559 E L ++ GLDVFE+EP + PGL E + +++PH+ + S T+ M +NV Sbjct: 257 EALDEGIVYSAGLDVFEEEPKIHPGLLENEKVILLPHLGTNSLETQYKMECAVLMNV 313
>YN14_YEAST (P53839) Putative 2-hydroxyacid dehydrogenase YNL274C (EC 1.-.-.-)| Length = 350 Score = 95.9 bits (237), Expect = 7e-20 Identities = 62/177 (35%), Positives = 93/177 (52%), Gaps = 1/177 (0%) Frame = +2 Query: 29 KGQTVGVIGAGRIGSAYA-RMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPV 205 +G+TVG++G GRIG R+ GF+ N IY + +Q E+ Y F Sbjct: 162 EGKTVGILGLGRIGRCILERLKPFGFE-NFIYHNRHQLPSEEEHGCEYVGF--------- 211 Query: 206 TWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVAL 385 EE L+ +D++S++ L+ T+HLIN E + MK V+VN +RG VIDE A+ Sbjct: 212 --------EEFLKRSDIVSVNVPLNHNTHHLINAETIEKMKDGVVIVNTARGAVIDEQAM 263 Query: 386 VEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALN 556 + L++ + GLDVFE EP + L M + +PH+ + S TR+ M L N Sbjct: 264 TDALRSGKIRSAGLDVFEYEPKISKELLSMSQVLGLPHMGTHSVETRKKMEELVVEN 320
>TKRA_BACSU (O32264) Probable 2-ketogluconate reductase (EC 1.1.1.215) (2KR)| Length = 325 Score = 94.4 bits (233), Expect = 2e-19 Identities = 58/177 (32%), Positives = 88/177 (49%), Gaps = 1/177 (0%) Frame = +2 Query: 35 QTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWK 214 QT+G+IG GRIG AR GF M ++Y + ++ E + Sbjct: 149 QTLGIIGMGRIGEQAARRAKFGFDMEVLYHNRHRKQETEDSIGV---------------- 192 Query: 215 RASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEH 394 + + ++ +L ++D I L L TYH+I +MK A+ VN SRG +DE AL+ Sbjct: 193 KYAELDTLLEQSDFILLITPLTDETYHMIGEREFKLMKNSAIFVNISRGKTVDEKALIRA 252 Query: 395 LKANPMFRVGLDVFEDEPYMKPG-LAEMKNAVVVPHIASASKWTREGMATLAALNVL 562 L+ + GLDV+E EP + L ++ N ++PHI SA+ R M AA N+L Sbjct: 253 LQEGWIRGAGLDVYEKEPVTQDNPLLQLDNVTLLPHIGSATAKVRFNMCKQAAENML 309
>SERA_BACSU (P35136) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 525 Score = 92.8 bits (229), Expect = 6e-19 Identities = 60/184 (32%), Positives = 94/184 (51%) Frame = +2 Query: 11 FVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKAN 190 +VG+ L G+T+G++G GRIGS A+ F M + FD + + K + Sbjct: 131 YVGSELYGKTLGIVGLGRIGSEIAQRR-GAFGMTVHVFDPFLTEERAKKIGV-------- 181 Query: 191 GEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVI 370 + + EEVL AD+I++H L K T L+N E +A KK L+N +RG +I Sbjct: 182 --------NSRTFEEVLESADIITVHTPLTKETKGLLNKETIAKTKKGVRLINCARGGII 233 Query: 371 DEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAA 550 DE AL+E L+ + LDVFE EP + L + + PH+ +++K + +A + Sbjct: 234 DEAALLEALENGHVAGAALDVFEVEPPVDNKLVDHPLVIATPHLGASTKEAQLNVAAQVS 293 Query: 551 LNVL 562 VL Sbjct: 294 EEVL 297
>CTBP1_RAT (Q9Z2F5) C-terminal-binding protein 1 (EC 1.1.1.-) (CtBP1)| (C-terminal-binding protein 3) (CtBP3) (50 kDa BFA-dependent ADP-ribosylation substrate) (BARS-50) Length = 430 Score = 89.0 bits (219), Expect = 9e-18 Identities = 58/180 (32%), Positives = 97/180 (53%), Gaps = 2/180 (1%) Frame = +2 Query: 26 LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPV 205 ++G+T+G+IG GR+G A A + + F N++++D Y S +E+ A G Q Sbjct: 161 IRGETLGIIGLGRVGQAVA-LRAKAFGFNVLFYDPYLSDGIER----------ALGLQ-- 207 Query: 206 TWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVAL 385 R S+++++L +D ++LH L++ +HLIN + M++ A LVN +RG ++DE AL Sbjct: 208 ---RVSTLQDLLFHSDCVTLHCGLNEHNHHLINDFTVKQMRQGAFLVNTARGGLVDEKAL 264 Query: 386 VEHLKANPMFRVGLDVFEDEP--YMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNV 559 + LK + LDV E EP + + L + N + PH A S+ M AA + Sbjct: 265 AQALKEGRIRGAALDVHESEPFSFSQGPLKDAPNLICTPHAAWYSEQASIEMREEAAREI 324
>CTBP1_MOUSE (O88712) C-terminal-binding protein 1 (EC 1.1.1.-) (CtBP1)| Length = 440 Score = 89.0 bits (219), Expect = 9e-18 Identities = 58/180 (32%), Positives = 97/180 (53%), Gaps = 2/180 (1%) Frame = +2 Query: 26 LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPV 205 ++G+T+G+IG GR+G A A + + F N++++D Y S +E+ A G Q Sbjct: 172 IRGETLGIIGLGRVGQAVA-LRAKAFGFNVLFYDPYLSDGIER----------ALGLQ-- 218 Query: 206 TWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVAL 385 R S+++++L +D ++LH L++ +HLIN + M++ A LVN +RG ++DE AL Sbjct: 219 ---RVSTLQDLLFHSDCVTLHCGLNEHNHHLINDFTVKQMRQGAFLVNTARGGLVDEKAL 275 Query: 386 VEHLKANPMFRVGLDVFEDEP--YMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNV 559 + LK + LDV E EP + + L + N + PH A S+ M AA + Sbjct: 276 AQALKEGRIRGAALDVHESEPFSFSQGPLKDAPNLICTPHAAWYSEQASIEMREEAAREI 335
>CTBP1_HUMAN (Q13363) C-terminal-binding protein 1 (EC 1.1.1.-) (CtBP1)| Length = 440 Score = 88.6 bits (218), Expect = 1e-17 Identities = 58/180 (32%), Positives = 97/180 (53%), Gaps = 2/180 (1%) Frame = +2 Query: 26 LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPV 205 ++G+T+G+IG GR+G A A + + F N++++D Y S +E+ A G Q Sbjct: 172 IRGETLGIIGLGRVGQAVA-LRAKAFGFNVLFYDPYLSDGVER----------ALGLQ-- 218 Query: 206 TWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVAL 385 R S+++++L +D ++LH L++ +HLIN + M++ A LVN +RG ++DE AL Sbjct: 219 ---RVSTLQDLLFHSDCVTLHCGLNEHNHHLINDFTVKQMRQGAFLVNTARGGLVDEKAL 275 Query: 386 VEHLKANPMFRVGLDVFEDEP--YMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNV 559 + LK + LDV E EP + + L + N + PH A S+ M AA + Sbjct: 276 AQALKEGRIRGAALDVHESEPFSFSQGPLKDAPNLICTPHAAWYSEQASIEMREEAAREI 335
>Y1556_HAEIN (P45250) Putative 2-hydroxyacid dehydrogenase HI1556 (EC 1.-.-.-)| Length = 315 Score = 88.2 bits (217), Expect = 1e-17 Identities = 58/168 (34%), Positives = 85/168 (50%), Gaps = 5/168 (2%) Frame = +2 Query: 26 LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPV 205 ++G T+GV G G +G+ R+ M ++Y + +T + T + Sbjct: 144 VRGSTLGVFGKGCLGTEVGRLA-NAVGMKVLYAEHKDATVCREGYTPF------------ 190 Query: 206 TWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVAL 385 +EVL++AD+++LH L +TT LIN E L+ MKK A L+N RGP+IDE+AL Sbjct: 191 --------DEVLKQADIVTLHCPLTETTKDLINAETLSKMKKGAFLINTGRGPLIDELAL 242 Query: 386 VEHLKANPMFRVGLDVFEDEPYMKP-----GLAEMKNAVVVPHIASAS 514 V+ LK + LDV EP K M N ++ PHIA AS Sbjct: 243 VDALKTGHLGGAALDVMVKEPPEKDNPLILAAKTMPNLIITPHIAWAS 290
>CTBPA_XENLA (Q9YHU0) C-terminal-binding protein A (CtBP)| Length = 440 Score = 87.8 bits (216), Expect = 2e-17 Identities = 58/180 (32%), Positives = 96/180 (53%), Gaps = 2/180 (1%) Frame = +2 Query: 26 LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPV 205 ++G+T+G+IG GR+G A A + + F N+ ++D Y S +E+ A G Q Sbjct: 172 IRGETLGIIGLGRVGQAVA-LRAKTFGFNVFFYDPYLSDGIER----------ALGLQ-- 218 Query: 206 TWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVAL 385 R S+++++L +D ++LH L++ +HLIN + M++ A LVN +RG ++DE AL Sbjct: 219 ---RVSTLQDLLFHSDCVTLHCGLNEHNHHLINDFTIKQMRQGAFLVNTARGGLVDEKAL 275 Query: 386 VEHLKANPMFRVGLDVFEDEP--YMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNV 559 + LK + LDV E EP + + L + N + PH A S+ M AA + Sbjct: 276 AQALKEGRIRGAALDVHESEPFSFTQGPLKDAPNLICTPHAAWYSEQASIEMREEAAREI 335
>LDHD_LACDE (P26297) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 332 Score = 87.8 bits (216), Expect = 2e-17 Identities = 48/144 (33%), Positives = 83/144 (57%) Frame = +2 Query: 14 VGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANG 193 +G ++ Q VGV+G G IG + ++M EGF +I +D++++ LEK G ++ Sbjct: 139 IGREVRDQVVGVVGTGHIGQVFMQIM-EGFGAKVIAYDIFRNPELEK----KGYYV---- 189 Query: 194 EQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVID 373 S++++ ++ADVISLH H+IN + +A MK++ V+VN SRGP++D Sbjct: 190 ---------DSLDDLYKQADVISLHVPDVPANVHMINDKSIAKMKQDVVIVNVSRGPLVD 240 Query: 374 EVALVEHLKANPMFRVGLDVFEDE 445 A++ L + +F +DV+E E Sbjct: 241 TDAVIRGLDSGKVFGYAMDVYEGE 264
>SERA_ARATH (O04130) D-3-phosphoglycerate dehydrogenase, chloroplast precursor| (EC 1.1.1.95) (3-PGDH) Length = 624 Score = 87.4 bits (215), Expect = 3e-17 Identities = 65/186 (34%), Positives = 94/186 (50%), Gaps = 1/186 (0%) Frame = +2 Query: 11 FVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKAN 190 +VG L G+T+ V+G G++G+ AR +G M +I D Y A +A Sbjct: 214 YVGVSLVGKTLAVMGFGKVGTEVARRA-KGLGMTVISHDPY----------APADRARAL 262 Query: 191 GEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVI 370 G V S ++ + AD +SLH L T + N E + MKK L+N +RG VI Sbjct: 263 GVDLV------SFDQAISTADFVSLHMPLTPATKKVFNDETFSKMKKGVRLINVARGGVI 316 Query: 371 DEVALVEHLKANPMFRVGLDVFEDEPYMKPG-LAEMKNAVVVPHIASASKWTREGMATLA 547 DE ALV L A + + LDVF +EP K L + +N V PH+ +++K +EG+A Sbjct: 317 DEDALVRALDAGIVAQAALDVFCEEPPSKDSRLIQHENVTVTPHLGASTKEAQEGVAIEI 376 Query: 548 ALNVLG 565 A V G Sbjct: 377 AEAVAG 382
>CTBP_DROME (O46036) C-terminal-binding protein (CtBP protein) (dCtBP)| Length = 476 Score = 87.4 bits (215), Expect = 3e-17 Identities = 54/180 (30%), Positives = 93/180 (51%), Gaps = 2/180 (1%) Frame = +2 Query: 26 LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPV 205 ++G T+G++G GRIGSA A + + F N+I++D Y ++K + Sbjct: 172 IRGDTLGLVGLGRIGSAVA-LRAKAFGFNVIFYDPYLPDGIDKSLGL------------- 217 Query: 206 TWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVAL 385 R +++++L ++D +SLH L++ +HLIN + M+ A LVN +RG ++D+ L Sbjct: 218 --TRVYTLQDLLFQSDCVSLHCTLNEHNHHLINEFTIKQMRPGAFLVNTARGGLVDDETL 275 Query: 386 VEHLKANPMFRVGLDVFEDEPY--MKPGLAEMKNAVVVPHIASASKWTREGMATLAALNV 559 LK + LDV E+EPY + L + N + PH A S + + +AA + Sbjct: 276 ALALKQGRIRAAALDVHENEPYNVFQGALKDAPNLICTPHAAFFSDASATELREMAATEI 335
>DDH_ZYMMO (P30799) 2-hydroxyacid dehydrogenase homolog (EC 1.1.1.-)| Length = 331 Score = 87.0 bits (214), Expect = 3e-17 Identities = 52/144 (36%), Positives = 77/144 (53%) Frame = +2 Query: 14 VGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANG 193 +G + +TVG+IG G IGS +A +M GF N+I + + L K V Sbjct: 138 IGLDVHDKTVGIIGVGHIGSVFAHIMTHGFGANVIAYKPHPDPELAKKVGF--------- 188 Query: 194 EQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVID 373 R +S++EV+ +D+ISLH L +H+IN E LA KK LVN SRG ++D Sbjct: 189 -------RFTSLDEVIETSDIISLHCPLTPENHHMINEETLARAKKGFYLVNTSRGGLVD 241 Query: 374 EVALVEHLKANPMFRVGLDVFEDE 445 A+++ LKA + DV+E+E Sbjct: 242 TKAVIKSLKAKHLGGYAADVYEEE 265
>CTBP2_MOUSE (P56546) C-terminal-binding protein 2 (CtBP2)| Length = 445 Score = 87.0 bits (214), Expect = 3e-17 Identities = 58/187 (31%), Positives = 98/187 (52%), Gaps = 6/187 (3%) Frame = +2 Query: 26 LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPV 205 ++G+T+G+IG GR G A A + + F ++I++D Y +E+ + Sbjct: 178 IRGETLGLIGFGRTGQAVA-VRAKAFGFSVIFYDPYLQDGIERSLGV------------- 223 Query: 206 TWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVAL 385 +R +++++L ++D +SLH L++ +HLIN + M++ A LVNA+RG ++DE AL Sbjct: 224 --QRVYTLQDLLYQSDCVSLHCNLNEHNHHLINDFTIKQMRQGAFLVNAARGGLVDEKAL 281 Query: 386 VEHLKANPMFRVGLDVFEDEP--YMKPGLAEMKNAVVVPHIA----SASKWTREGMATLA 547 + LK + LDV E EP + + L + N + PH A AS RE AT Sbjct: 282 AQALKEGRIRGAALDVHESEPFSFAQGPLKDAPNLICTPHTAWYSEQASLEMREAAATEI 341 Query: 548 ALNVLGK 568 + G+ Sbjct: 342 RRAITGR 348
>CTBP2_HUMAN (P56545) C-terminal-binding protein 2 (CtBP2)| Length = 445 Score = 87.0 bits (214), Expect = 3e-17 Identities = 58/187 (31%), Positives = 98/187 (52%), Gaps = 6/187 (3%) Frame = +2 Query: 26 LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPV 205 ++G+T+G+IG GR G A A + + F ++I++D Y +E+ + Sbjct: 178 IRGETLGLIGFGRTGQAVA-VRAKAFGFSVIFYDPYLQDGIERSLGV------------- 223 Query: 206 TWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVAL 385 +R +++++L ++D +SLH L++ +HLIN + M++ A LVNA+RG ++DE AL Sbjct: 224 --QRVYTLQDLLYQSDCVSLHCNLNEHNHHLINDFTIKQMRQGAFLVNAARGGLVDEKAL 281 Query: 386 VEHLKANPMFRVGLDVFEDEP--YMKPGLAEMKNAVVVPHIA----SASKWTREGMATLA 547 + LK + LDV E EP + + L + N + PH A AS RE AT Sbjct: 282 AQALKEGRIRGAALDVHESEPFSFAQGPLKDAPNLICTPHTAWYSEQASLEMREAAATEI 341 Query: 548 ALNVLGK 568 + G+ Sbjct: 342 RRAITGR 348
>SERA_ARCFU (O29445) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 527 Score = 85.5 bits (210), Expect = 1e-16 Identities = 57/185 (30%), Positives = 95/185 (51%), Gaps = 1/185 (0%) Frame = +2 Query: 11 FVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKAN 190 F+G L+G+T GVIG GR+G A+ + +MN++ +D + S K Sbjct: 132 FMGIELRGKTAGVIGLGRVGFEVAKRC-KALEMNVLAYDPFVS--------------KER 176 Query: 191 GEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVI 370 EQ + + +L +DVI++H K T LI + MK ++VNA+RG ++ Sbjct: 177 AEQ--IGVKLVDFDTLLASSDVITVHVPRTKETIGLIGKGQFEKMKDGVIVVNAARGGIV 234 Query: 371 DEVALVEHLKANPMFRVGLDVFEDEPYMKPG-LAEMKNAVVVPHIASASKWTREGMATLA 547 DE AL E +KA + LDV+E EP L ++ N V PHIA++++ + + + Sbjct: 235 DEAALYEAIKAGKVAAAALDVYEKEPPSPDNPLLKLDNVVTTPHIAASTREAQLNVGMII 294 Query: 548 ALNVL 562 A +++ Sbjct: 295 AEDIV 299
>CTBPB_XENLA (Q9W758) C-terminal-binding protein B (TCF-3 corepressor CtBP)| (XCtBP) Length = 437 Score = 85.5 bits (210), Expect = 1e-16 Identities = 51/162 (31%), Positives = 88/162 (54%), Gaps = 2/162 (1%) Frame = +2 Query: 26 LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPV 205 ++G+T+G+IG GRIG A A + + F +I++D Y + +E+ + Sbjct: 175 IRGETLGIIGLGRIGQAVA-LRAKAFNFTVIFYDPYLADGVERSLGL------------- 220 Query: 206 TWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVAL 385 +R ++++E+L +D I+LH L++ +HLIN + M++ LVN +RG ++DE AL Sbjct: 221 --QRMATLQELLMHSDCITLHCNLNEHNHHLINDFTIKQMRQGCFLVNTARGGLVDEKAL 278 Query: 386 VEHLKANPMFRVGLDVFEDEP--YMKPGLAEMKNAVVVPHIA 505 + LK + LDV E EP + + L + N + PH A Sbjct: 279 AQALKDGRIRGAALDVHESEPFSFSQGPLKDAPNLICTPHTA 320
>PDXB_VIBVU (Q8DB36) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 377 Score = 85.1 bits (209), Expect = 1e-16 Identities = 55/161 (34%), Positives = 88/161 (54%), Gaps = 4/161 (2%) Frame = +2 Query: 35 QTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWK 214 QTVG+IGAG++GS Y + ++G + ++ D F + G++ + Sbjct: 118 QTVGIIGAGQVGS-YLQQCLQGIGIKVLIND---------------PFKQEEGDE----R 157 Query: 215 RASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVA 382 +S++ +L+EADVI+LH + + T+HLIN E L ++ + +L+NA+RGPV+D A Sbjct: 158 EFTSLDRLLQEADVITLHTPITRDGKYPTHHLINEEILNSLRADQILINAARGPVVDNQA 217 Query: 383 LVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIA 505 L L+ F LDVFE EP + L + A PH+A Sbjct: 218 LKRRLQQADGFMAALDVFEFEPEVDMELLPLL-AFATPHVA 257
>PDXB_VIBVY (Q7MIT6) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 377 Score = 84.7 bits (208), Expect = 2e-16 Identities = 54/161 (33%), Positives = 88/161 (54%), Gaps = 4/161 (2%) Frame = +2 Query: 35 QTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWK 214 QTVG++GAG++GS Y + ++G + ++ D F + G++ + Sbjct: 118 QTVGIVGAGQVGS-YLQQCLQGIGIKVLIND---------------PFKQEEGDE----R 157 Query: 215 RASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVA 382 +S++ +L+EADVI+LH + + T+HLIN E L ++ + +L+NA+RGPV+D A Sbjct: 158 EFTSLDRLLQEADVITLHTPITRDGKYPTHHLINKEILNSLRADQILINAARGPVVDNQA 217 Query: 383 LVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIA 505 L L+ F LDVFE EP + L + A PH+A Sbjct: 218 LKHRLQQADGFTAALDVFEFEPEVDMELLPLL-AFATPHVA 257
>DHGY_METEX (Q59516) Glycerate dehydrogenase (EC 1.1.1.29) (NADH-dependent| hydroxypyruvate reductase) (HPR) (GDH) (Hydroxypyruvate dehydrogenase) (Glyoxylate reductase) (HPR-A) Length = 313 Score = 84.3 bits (207), Expect = 2e-16 Identities = 56/177 (31%), Positives = 88/177 (49%), Gaps = 3/177 (1%) Frame = +2 Query: 26 LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPV 205 + G T+G+IG G +G + A+ E M ++ FD++ L Sbjct: 144 IAGSTLGIIGYGALGKSIAKRA-EALGMKVLAFDVFPQDGLV------------------ 184 Query: 206 TWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVAL 385 +E +L ++DVI+LH L T ++I E+L MK+ A+L+N +RG ++DE AL Sbjct: 185 ------DLETILTQSDVITLHVPLTPDTKNMIGAEQLKKMKRSAILINTARGGLVDEAAL 238 Query: 386 VEHLKANPMFRVGLDVFEDEPYMKPGL---AEMKNAVVVPHIASASKWTREGMATLA 547 ++ LK + G DV EP + A++ N +V PH+A ASK E M LA Sbjct: 239 LQALKDGTIGGAGFDVVAQEPPKDGNILCDADLPNLIVTPHVAWASK---EAMQILA 292
>SERA_MYCLE (O33116) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 528 Score = 84.0 bits (206), Expect = 3e-16 Identities = 59/183 (32%), Positives = 88/183 (48%) Frame = +2 Query: 11 FVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKAN 190 F G + G+TVGV+G GRIG A I F ++I +D Y A Sbjct: 134 FSGTEIFGKTVGVVGLGRIGQLVAAR-IAAFGAHVIAYDPYV----------------AP 176 Query: 191 GEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVI 370 S +++L AD IS+H T LI+ E LA K ++VNA+RG ++ Sbjct: 177 ARAAQLGIELMSFDDLLARADFISVHLPKTPETAGLIDKEALAKTKPGVIIVNAARGGLV 236 Query: 371 DEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAA 550 DEVAL + +++ + GLDVF EP L E+ VV PH+ +++ ++ T A Sbjct: 237 DEVALADAVRSGHVRAAGLDVFATEPCTDSPLFELSQVVVTPHLGASTAEAQDRAGTDVA 296 Query: 551 LNV 559 +V Sbjct: 297 ESV 299
>LDHD_LACHE (P30901) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 336 Score = 83.2 bits (204), Expect = 5e-16 Identities = 48/144 (33%), Positives = 80/144 (55%) Frame = +2 Query: 14 VGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANG 193 +G ++ Q VGV+G G IG + R+M EGF +I +D++++ LEK G ++ Sbjct: 139 IGREVRDQVVGVVGTGHIGQVFMRIM-EGFGAKVIAYDIFKNPELEK----KGYYV---- 189 Query: 194 EQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVID 373 S++++ ++ADVISLH H+IN + +A MK V+VN SRG ++D Sbjct: 190 ---------DSLDDLYKQADVISLHVPDVPANVHMINDKSIAEMKDGVVIVNCSRGRLVD 240 Query: 374 EVALVEHLKANPMFRVGLDVFEDE 445 A++ L + +F +D +EDE Sbjct: 241 TDAVIRGLDSGKIFGFVMDTYEDE 264
>DDH_HAEIN (P44501) 2-hydroxyacid dehydrogenase homolog (EC 1.1.1.-)| Length = 331 Score = 82.4 bits (202), Expect = 8e-16 Identities = 49/144 (34%), Positives = 84/144 (58%) Frame = +2 Query: 14 VGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANG 193 +G + G+TVGVIG G+IG A R++ +GF MN++ +D +++ +E+ GQ+++ Sbjct: 138 IGFNMYGRTVGVIGTGKIGIAVMRIL-KGFGMNILAYDPFKNPVVEELG---GQYVE--- 190 Query: 194 EQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVID 373 ++E+ ++ VI+LH YHL+N E A MK ++VN SRG +ID Sbjct: 191 -----------LDELYAKSHVITLHCPATPENYHLLNCEAFAKMKDGVMIVNTSRGSLID 239 Query: 374 EVALVEHLKANPMFRVGLDVFEDE 445 A ++ LK + +G+DV+E+E Sbjct: 240 TQAAIDALKQRKIGALGMDVYENE 263
>LDHD_ECOLI (P52643) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH)| (Fermentative lactate dehydrogenase) Length = 329 Score = 81.6 bits (200), Expect = 1e-15 Identities = 51/143 (35%), Positives = 72/143 (50%) Frame = +2 Query: 17 GNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGE 196 G + G+T GVIG G+IG A R++ +GF M L+ FD Y S + Y Sbjct: 139 GFTMYGKTAGVIGTGKIGVAMLRIL-KGFGMRLLAFDPYPSAAALELGVEY--------- 188 Query: 197 QPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDE 376 + + E+DVISLH L YHL+N MK ++VN SRG +ID Sbjct: 189 --------VDLPTLFSESDVISLHCPLTPENYHLLNEAAFEQMKNGVMIVNTSRGALIDS 240 Query: 377 VALVEHLKANPMFRVGLDVFEDE 445 A +E LK + +G+DV+E+E Sbjct: 241 QAAIEALKNQKIGSLGMDVYENE 263
>PDXB_PHOLL (Q7N2B2) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 375 Score = 81.3 bits (199), Expect = 2e-15 Identities = 59/176 (33%), Positives = 94/176 (53%), Gaps = 5/176 (2%) Frame = +2 Query: 26 LKGQTVGVIGAGRIGSAYA-RMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQP 202 LK + VG++G G +GS A R+ + G + L R ++ G+ Sbjct: 114 LKDKVVGIVGVGNVGSRLAERLAVLGIRTLLC-----DPPRADR------------GDAG 156 Query: 203 VTWKRASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVI 370 W S+E++++EAD+++ H L+K+ T+HL++ E L+++ +L+NASRG VI Sbjct: 157 EFW----SLEKLVKEADILTFHTPLNKSGPYKTHHLVDVELLSVLPDNRILINASRGEVI 212 Query: 371 DEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 538 D AL+ LK RV LDV+E EP + L E+ + + PHIA +T EG A Sbjct: 213 DNQALLTALKCGKKLRVVLDVWEPEPDLSLPLLELVD-IGTPHIAG---YTLEGKA 264
>SERA_MYCTU (P0A544) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 528 Score = 81.3 bits (199), Expect = 2e-15 Identities = 59/183 (32%), Positives = 88/183 (48%) Frame = +2 Query: 11 FVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKAN 190 F G + G+TVGV+G GRIG A+ I F ++ +D Y S A Sbjct: 134 FSGTEIFGKTVGVVGLGRIGQLVAQR-IAAFGAYVVAYDPYVSP--------------AR 178 Query: 191 GEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVI 370 Q S++++L AD IS+H T LI+ E LA K ++VNA+RG ++ Sbjct: 179 AAQ--LGIELLSLDDLLARADFISVHLPKTPETAGLIDKEALAKTKPGVIIVNAARGGLV 236 Query: 371 DEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAA 550 DE AL + + + GLDVF EP L E+ VV PH+ +++ ++ T A Sbjct: 237 DEAALADAITGGHVRAAGLDVFATEPCTDSPLFELAQVVVTPHLGASTAEAQDRAGTDVA 296 Query: 551 LNV 559 +V Sbjct: 297 ESV 299
>SERA_MYCBO (P0A545) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 528 Score = 81.3 bits (199), Expect = 2e-15 Identities = 59/183 (32%), Positives = 88/183 (48%) Frame = +2 Query: 11 FVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKAN 190 F G + G+TVGV+G GRIG A+ I F ++ +D Y S A Sbjct: 134 FSGTEIFGKTVGVVGLGRIGQLVAQR-IAAFGAYVVAYDPYVSP--------------AR 178 Query: 191 GEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVI 370 Q S++++L AD IS+H T LI+ E LA K ++VNA+RG ++ Sbjct: 179 AAQ--LGIELLSLDDLLARADFISVHLPKTPETAGLIDKEALAKTKPGVIIVNAARGGLV 236 Query: 371 DEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAA 550 DE AL + + + GLDVF EP L E+ VV PH+ +++ ++ T A Sbjct: 237 DEAALADAITGGHVRAAGLDVFATEPCTDSPLFELAQVVVTPHLGASTAEAQDRAGTDVA 296 Query: 551 LNV 559 +V Sbjct: 297 ESV 299
>SERA_HAEIN (P43885) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 410 Score = 80.9 bits (198), Expect = 2e-15 Identities = 53/176 (30%), Positives = 91/176 (51%), Gaps = 6/176 (3%) Frame = +2 Query: 26 LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPV 205 ++G+ +G+IG G IGS + ++ E M++ ++D+ L Sbjct: 150 VRGKKLGIIGYGHIGSQLS-IIAESLGMDVYFYDIENKLPLGNA---------------- 192 Query: 206 TWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVAL 385 K+ S+EE+L DV+SLH +T +L+N R+A +K+ A+L+NA+RG V+D AL Sbjct: 193 --KQVRSLEELLSSCDVVSLHVPELPSTKNLMNVARIAQLKQGAILINAARGTVVDIDAL 250 Query: 386 VEHLKANPMFRVGLDVFEDEP------YMKPGLAEMKNAVVVPHIASASKWTREGM 535 + LK + +DVF EP ++ P L E N ++ PHI ++ +E + Sbjct: 251 AQALKDGKLQGAAIDVFPVEPASINEEFISP-LREFDNVILTPHIGGSTAEAQENI 305
>DHGY_HYPME (P36234) Glycerate dehydrogenase (EC 1.1.1.29) (NADH-dependent| hydroxypyruvate reductase) (HPR) (GDH) (Hydroxypyruvate dehydrogenase) (Glyoxylate reductase) Length = 321 Score = 80.1 bits (196), Expect = 4e-15 Identities = 51/179 (28%), Positives = 86/179 (48%) Frame = +2 Query: 2 PHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFL 181 P VG L +T+G+ G G IG A A+ +GF M++ YFD ++++ Sbjct: 137 PLELVGEKLDNKTLGIYGFGSIGQALAKRA-QGFDMDIDYFDTHRAS------------- 182 Query: 182 KANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRG 361 ++ E S++ +L + SL+ T + N + + + A++VN +RG Sbjct: 183 -SSDEASYQATFHDSLDSLLSVSQFFSLNAPSTPETRYFFNKATIKSLPQGAIVVNTARG 241 Query: 362 PVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 538 ++D +V L+A + G DVF EP + G ++ N + PHI SA+ RE MA Sbjct: 242 DLVDNELVVAALEAGRLAYAGFDVFAGEPNINEGYYDLPNTFLFPHIGSAATQAREDMA 300
>LDHD_TREPA (O83080) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 331 Score = 79.0 bits (193), Expect = 9e-15 Identities = 58/184 (31%), Positives = 87/184 (47%), Gaps = 14/184 (7%) Frame = +2 Query: 26 LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPV 205 L+ VG++G GRIG A AR+ +G ++ FD Y + ++++T Sbjct: 144 LRCSRVGILGTGRIGQAAARLF-KGVGAQVVGFDPYPNDAAKEWLTYV------------ 190 Query: 206 TWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVAL 385 SM+E+L +DVISLH K ++HLIN + +A MK LVN +RG VID AL Sbjct: 191 ------SMDELLSTSDVISLHMPATKDSHHLINAKTIAQMKDGVYLVNTARGAVIDSQAL 244 Query: 386 VEHLKANPMFRVGLDVFEDE-PYMKPG-------------LAEMKNAVVVPHIASASKWT 523 ++ L + LD +E E PY+ L + + PHIA ++ Sbjct: 245 LDSLDKGKIAGAALDAYEFEGPYIPKDNGNNPITDTVYARLVAHERIIYTPHIAFYTETA 304 Query: 524 REGM 535 E M Sbjct: 305 IENM 308
>SERA_SYNY3 (P73821) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 554 Score = 78.6 bits (192), Expect = 1e-14 Identities = 53/176 (30%), Positives = 86/176 (48%) Frame = +2 Query: 11 FVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKAN 190 F+G + +T+GV+G G+IGS A + + M L+ +D + S + Sbjct: 160 FIGTEVYKKTLGVVGLGKIGSHVAGVA-KAMGMKLLAYDPFISQERADQIGC-------- 210 Query: 191 GEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVI 370 ++ + EAD I+LH T +LIN E LA MK A ++N SRG +I Sbjct: 211 --------TLVDLDLLFSEADFITLHIPKTPETANLINAETLAKMKPTARIINCSRGGII 262 Query: 371 DEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 538 DE ALV ++ + LDVF EP + L E N ++ PH+ ++++ + +A Sbjct: 263 DEEALVTAIETAQIGGAALDVFAQEPLGESRLREFSNVILTPHLGASTEEAQVNVA 318
>PDXB_VIBCH (Q9KQ92) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 381 Score = 78.2 bits (191), Expect = 2e-14 Identities = 53/161 (32%), Positives = 85/161 (52%), Gaps = 4/161 (2%) Frame = +2 Query: 35 QTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWK 214 +TVG+IGAG++GS Y + G M ++ D + +A G++ + Sbjct: 118 KTVGIIGAGQVGS-YLAKCLSGIGMKVLLNDPPK---------------QAQGDE----R 157 Query: 215 RASSMEEVLREADVISLHPVLDK----TTYHLINPERLAMMKKEAVLVNASRGPVIDEVA 382 + +E +L++ADVI+LH + + T+HLI+ L ++ + +L+NA+RGPV+D A Sbjct: 158 EFTELETLLKQADVITLHTPITRGGEWPTHHLIDAAILEQLRSDQILINAARGPVVDNAA 217 Query: 383 LVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIA 505 L L+ F LDVFE EP + L + A PHIA Sbjct: 218 LKARLQQGDGFTAVLDVFEFEPQVDMELLPLL-AFATPHIA 257
>SERA_SCHPO (P87228) Putative D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95)| (3-PGDH) Length = 466 Score = 77.0 bits (188), Expect = 3e-14 Identities = 50/177 (28%), Positives = 86/177 (48%), Gaps = 13/177 (7%) Frame = +2 Query: 26 LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPV 205 ++G+T+G+IG G IGS + ++ E ++++Y+D+ L Sbjct: 193 IRGKTLGIIGYGHIGSQLS-VLAEAMGLHVVYYDILPIMPLGSA---------------- 235 Query: 206 TWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVAL 385 K+ SS+ E+L AD +SLH T ++I+ + A MK+ + L+NASRG V+D AL Sbjct: 236 --KQLSSLPELLHRADFVSLHVPASPETKNMISSKEFAAMKEGSYLINASRGTVVDIPAL 293 Query: 386 VEHLKANPMFRVGLDVFEDEP-------------YMKPGLAEMKNAVVVPHIASASK 517 V+ K+ + +DV+ EP L KN ++ PHI +++ Sbjct: 294 VDASKSGKIAGAAIDVYPSEPAGNGKDKFVDSLNSWTSELTHCKNIILTPHIGGSTE 350
>GRHPR_HUMAN (Q9UBQ7) Glyoxylate reductase/hydroxypyruvate reductase (EC| 1.1.1.79) Length = 328 Score = 77.0 bits (188), Expect = 3e-14 Identities = 61/188 (32%), Positives = 87/188 (46%), Gaps = 1/188 (0%) Frame = +2 Query: 2 PHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFL 181 P G L TVG+IG GRIG A AR + +Y + R E+ +F+ Sbjct: 143 PLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTG--RQPRPEEAAEFQAEFV 200 Query: 182 KANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRG 361 S E+ ++D I + L T L N + MK+ AV +N SRG Sbjct: 201 --------------STPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISRG 246 Query: 362 PVIDEVALVEHLKANPMFRVGLDVFEDEPY-MKPGLAEMKNAVVVPHIASASKWTREGMA 538 V+++ L + L + + GLDV EP L +KN V++PHI SA+ TR M+ Sbjct: 247 DVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIGSATHRTRNTMS 306 Query: 539 TLAALNVL 562 LAA N+L Sbjct: 307 LLAANNLL 314
>SERA_MACFA (Q60HD7) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH)| Length = 532 Score = 76.6 bits (187), Expect = 4e-14 Identities = 52/169 (30%), Positives = 83/169 (49%) Frame = +2 Query: 11 FVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKAN 190 F+G L G+T+G++G GRIG A M + F M I +D S + + Sbjct: 137 FMGTELNGKTLGILGLGRIGREVATRM-QSFGMKTIGYDPIISPEVSA----------SF 185 Query: 191 GEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVI 370 G Q + +EE+ D I++H L +T L+N A KK +VN +RG ++ Sbjct: 186 GVQQLP------LEEIWPLCDFITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGGIV 239 Query: 371 DEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASK 517 DE AL+ L++ LDVF +EP L + +N + PH+ +++K Sbjct: 240 DEGALLRALQSGQCAGAALDVFTEEPPRDRALVDHENVISCPHLGASTK 288
>SERA_HUMAN (O43175) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH)| Length = 532 Score = 76.6 bits (187), Expect = 4e-14 Identities = 52/169 (30%), Positives = 83/169 (49%) Frame = +2 Query: 11 FVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKAN 190 F+G L G+T+G++G GRIG A M + F M I +D S + + Sbjct: 137 FMGTELNGKTLGILGLGRIGREVATRM-QSFGMKTIGYDPIISPEVSA----------SF 185 Query: 191 GEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVI 370 G Q + +EE+ D I++H L +T L+N A KK +VN +RG ++ Sbjct: 186 GVQQLP------LEEIWPLCDFITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGGIV 239 Query: 371 DEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASK 517 DE AL+ L++ LDVF +EP L + +N + PH+ +++K Sbjct: 240 DEGALLRALQSGQCAGAALDVFTEEPPRDRALVDHENVISCPHLGASTK 288
>SERA_YEAST (P40054) D-3-phosphoglycerate dehydrogenase 1 (EC 1.1.1.95) (3-PGDH| 1) Length = 469 Score = 76.3 bits (186), Expect = 6e-14 Identities = 49/178 (27%), Positives = 93/178 (52%), Gaps = 14/178 (7%) Frame = +2 Query: 26 LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPV 205 ++G+T+G+IG G IGS + ++ E ++++Y+D+ + A G Sbjct: 196 VRGKTLGIIGYGHIGSQLS-VLAEAMGLHVLYYDIVT-------IMALG----------- 236 Query: 206 TWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVAL 385 T ++ S+++E+L ++D ++LH T +++ + A MK A ++NASRG V+D +L Sbjct: 237 TARQVSTLDELLNKSDFVTLHVPATPETEKMLSAPQFAAMKDGAYVINASRGTVVDIPSL 296 Query: 386 VEHLKANPMFRVGLDVFEDEPYMKPG--------------LAEMKNAVVVPHIASASK 517 ++ +KAN + LDV+ EP K G L + N ++ PHI +++ Sbjct: 297 IQAVKANKIAGAALDVYPHEP-AKNGEGSFNDELNSWTSELVSLPNIILTPHIGGSTE 353
>SER33_YEAST (P40510) D-3-phosphoglycerate dehydrogenase 2 (EC 1.1.1.95) (3-PGDH| 2) Length = 469 Score = 76.3 bits (186), Expect = 6e-14 Identities = 49/178 (27%), Positives = 93/178 (52%), Gaps = 14/178 (7%) Frame = +2 Query: 26 LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPV 205 ++G+T+G+IG G IGS + ++ E ++++Y+D+ + A G Sbjct: 196 VRGKTLGIIGYGHIGSQLS-VLAEAMGLHVLYYDIVT-------IMALG----------- 236 Query: 206 TWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVAL 385 T ++ S+++E+L ++D ++LH T +++ + A MK A ++NASRG V+D +L Sbjct: 237 TARQVSTLDELLNKSDFVTLHVPATPETEKMLSAPQFAAMKDGAYVINASRGTVVDIPSL 296 Query: 386 VEHLKANPMFRVGLDVFEDEPYMKPG--------------LAEMKNAVVVPHIASASK 517 ++ +KAN + LDV+ EP K G L + N ++ PHI +++ Sbjct: 297 IQAVKANKIAGAALDVYPHEP-AKNGEGSFNDELNSWTSELVSLPNIILTPHIGGSTE 353
>SERA_RAT (O08651) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH)| Length = 532 Score = 76.3 bits (186), Expect = 6e-14 Identities = 50/169 (29%), Positives = 83/169 (49%) Frame = +2 Query: 11 FVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKAN 190 F+G L G+T+G++G GRIG A M + F M + +D S + ++G Sbjct: 137 FMGTELNGKTLGILGLGRIGREVAARM-QAFGMKTVGYDPIISPEV---AASFGV----- 187 Query: 191 GEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVI 370 + +EE+ D I++H L +T L+N A KK +VN +RG ++ Sbjct: 188 --------QQLPLEEIWPLCDFITVHTPLLPSTTGLLNDSTFAQCKKGVRVVNCARGGIV 239 Query: 371 DEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASK 517 DE AL+ L++ LDVF +EP L + +N + PH+ +++K Sbjct: 240 DEGALLRALQSGQCAGAALDVFTEEPPRDRALVDHENVISCPHLGASTK 288
>SERA_MOUSE (Q61753) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH)| (A10) Length = 532 Score = 76.3 bits (186), Expect = 6e-14 Identities = 50/169 (29%), Positives = 83/169 (49%) Frame = +2 Query: 11 FVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKAN 190 F+G L G+T+G++G GRIG A M + F M + +D S + ++G Sbjct: 137 FMGTELNGKTLGILGLGRIGREVATRM-QSFGMKTVGYDPIISPEV---AASFGV----- 187 Query: 191 GEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVI 370 + +EE+ D I++H L +T L+N A KK +VN +RG ++ Sbjct: 188 --------QQLPLEEIWPLCDFITVHTPLLPSTTGLLNDSTFAQCKKGVRVVNCARGGIV 239 Query: 371 DEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASK 517 DE AL+ L++ LDVF +EP L + +N + PH+ +++K Sbjct: 240 DEGALLRALQSGQCAGAALDVFTEEPPRDRALVDHENVISCPHLGASTK 288
>PDXB_PSEAE (Q9I3W9) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 380 Score = 75.5 bits (184), Expect = 1e-13 Identities = 58/167 (34%), Positives = 82/167 (49%), Gaps = 4/167 (2%) Frame = +2 Query: 26 LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPV 205 L +T GV+GAG++G ++ G ++ D + R G+F+ Sbjct: 114 LAERTYGVVGAGQVGGRLVEVL-RGLGWKVLVCDPPRQAREPD-----GEFV-------- 159 Query: 206 TWKRASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVID 373 S+E +L EADVISLH L++ T HL++ RLA ++ LVNASRG V+D Sbjct: 160 ------SLERLLAEADVISLHTPLNRDGEHPTRHLLDEPRLAALRPGTWLVNASRGAVVD 213 Query: 374 EVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 514 AL L+ V LDV+E EP P LA + + PHIA S Sbjct: 214 NQALRRLLEGGADLEVALDVWEGEPQADPELA-ARCLIATPHIAGYS 259
>LDHD_STAAR (Q6GDS2) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 75.1 bits (183), Expect = 1e-13 Identities = 54/174 (31%), Positives = 86/174 (49%), Gaps = 14/174 (8%) Frame = +2 Query: 26 LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPV 205 +K TV +IG GRIG+A A++ GF + +D Y + L+ FL Sbjct: 144 VKNMTVAIIGTGRIGAATAKIYA-GFGATITAYDAYPNKDLD--------FL-------- 186 Query: 206 TWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVAL 385 T+K S++E +++AD+ISLH +K +YHL + +KK A+LVNA+RG VI+ L Sbjct: 187 TYK--DSVKEAIKDADIISLHVPANKESYHLFDKTMFDHVKKGAILVNAARGAVINTPDL 244 Query: 386 VEHLKANPMFRVGLDVFEDEPYMKPG--------------LAEMKNAVVVPHIA 505 ++ + + +D +E+E L E + +V PHIA Sbjct: 245 IDAVNDGTLLGAAIDTYENEAAYFTNDWTNKDIDDKTLLELIEHERILVTPHIA 298
>PDXB_VIBPA (Q87MN8) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 377 Score = 75.1 bits (183), Expect = 1e-13 Identities = 50/161 (31%), Positives = 85/161 (52%), Gaps = 4/161 (2%) Frame = +2 Query: 35 QTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWK 214 +TVG+IGAG++GS Y ++G +N++ D + K P ++ Sbjct: 118 KTVGIIGAGQVGS-YLEKCLKGMGINVLINDPF----------------KQEAGDPRSF- 159 Query: 215 RASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVA 382 + + E++ ++D+I+LH + K T+HLI+ + L ++ + +L+NA+RGPV+D A Sbjct: 160 --TPLAELIEQSDIITLHTPITKDGLHPTHHLIDEKVLNGLRGDQILINAARGPVVDNQA 217 Query: 383 LVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIA 505 L + L F LDVFE EP + L + A PH+A Sbjct: 218 LKQRLMKQDGFTAALDVFEFEPEVDMELLPLL-AFATPHVA 257
>LDHD_STRP1 (Q99ZM2) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 74.7 bits (182), Expect = 2e-13 Identities = 50/147 (34%), Positives = 77/147 (52%), Gaps = 1/147 (0%) Frame = +2 Query: 17 GNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGE 196 G +L TV +IG GRIG A A++ +GF ++ +D+YQS K V Y + Sbjct: 140 GRVLGDMTVAIIGTGRIGLATAKIF-KGFGCKVVGYDIYQSDAA-KAVLDYKE------- 190 Query: 197 QPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDE 376 S+EE +++AD++SLH HL N + KK A+L+N +RG VI+ Sbjct: 191 ---------SVEEAIKDADLVSLHMPPTAENTHLFNSDLFKSFKKGAILMNMARGAVIET 241 Query: 377 VALVEHLKANPMFRVGLDVFEDE-PYM 454 L++ L A + G+D +E E PY+ Sbjct: 242 QDLLDALDAGLLSGAGIDTYEFEGPYI 268
>LDHD_LEUMC (P51011) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 331 Score = 74.3 bits (181), Expect = 2e-13 Identities = 54/177 (30%), Positives = 91/177 (51%), Gaps = 14/177 (7%) Frame = +2 Query: 17 GNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGE 196 G ++ QTVGVIG G IG A +++GF +I +D Y + L+ A G ++ Sbjct: 140 GREMRMQTVGVIGTGHIGRV-AINILKGFGAKVIAYDKYPNAELQ----AEGLYV----- 189 Query: 197 QPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDE 376 +++E+ +AD ISL+ +HLIN + +A MK V++NA+RG ++D Sbjct: 190 --------DTLDELYAQADAISLYVPGVPENHHLINADAIAKMKDGVVIMNAARGNLMDI 241 Query: 377 VALVEHLKANPMFRVGLDVFEDEP--YMKPGLAE------------MKNAVVVPHIA 505 A+++ L + + G+DV+E+E MK GL + +N ++ PH A Sbjct: 242 DAIIDGLNSGKISDFGMDVYENEVACSMKIGLVKNSPDAKIADLIARENVMITPHTA 298
>LDHD_STAAW (Q8NUT2) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 73.9 bits (180), Expect = 3e-13 Identities = 54/174 (31%), Positives = 85/174 (48%), Gaps = 14/174 (8%) Frame = +2 Query: 26 LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPV 205 +K TV +IG GRIG+A A++ GF + +D Y + L+ FL Sbjct: 144 VKNMTVAIIGTGRIGAATAKIYA-GFGATITAYDAYPNKDLD--------FL-------- 186 Query: 206 TWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVAL 385 T+K S++E +++AD+ISLH +K +YHL + +KK A+LVNA+RG VI+ L Sbjct: 187 TYK--DSVKEAIKDADIISLHVPANKESYHLFDKAMFDHVKKGAILVNAARGAVINTPDL 244 Query: 386 VEHLKANPMFRVGLDVFEDEPYMKPG--------------LAEMKNAVVVPHIA 505 + + + +D +E+E L E + +V PHIA Sbjct: 245 IAAVNDGTLLGAAIDTYENEAAYFTNDWTNKDIDDKTLLELIEHERILVTPHIA 298
>LDHD_STAAU (P72357) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 73.9 bits (180), Expect = 3e-13 Identities = 54/174 (31%), Positives = 85/174 (48%), Gaps = 14/174 (8%) Frame = +2 Query: 26 LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPV 205 +K TV +IG GRIG+A A++ GF + +D Y + L+ FL Sbjct: 144 VKNMTVAIIGTGRIGAATAKIYA-GFGATITAYDAYPNKDLD--------FL-------- 186 Query: 206 TWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVAL 385 T+K S++E +++AD+ISLH +K +YHL + +KK A+LVNA+RG VI+ L Sbjct: 187 TYK--DSVKEAIKDADIISLHVPANKESYHLFDKAMFDHVKKGAILVNAARGAVINTPDL 244 Query: 386 VEHLKANPMFRVGLDVFEDEPYMKPG--------------LAEMKNAVVVPHIA 505 + + + +D +E+E L E + +V PHIA Sbjct: 245 IAAVNDGTLLGAAIDTYENEAAYFTNDWTNKDIDDKTLLELIEHERILVTPHIA 298
>LDHD_STAAS (Q6G6F1) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 73.9 bits (180), Expect = 3e-13 Identities = 54/174 (31%), Positives = 85/174 (48%), Gaps = 14/174 (8%) Frame = +2 Query: 26 LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPV 205 +K TV +IG GRIG+A A++ GF + +D Y + L+ FL Sbjct: 144 VKNMTVAIIGTGRIGAATAKIYA-GFGATITAYDAYPNKDLD--------FL-------- 186 Query: 206 TWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVAL 385 T+K S++E +++AD+ISLH +K +YHL + +KK A+LVNA+RG VI+ L Sbjct: 187 TYK--DSVKEAIKDADIISLHVPANKESYHLFDKAMFDHVKKGAILVNAARGAVINTPDL 244 Query: 386 VEHLKANPMFRVGLDVFEDEPYMKPG--------------LAEMKNAVVVPHIA 505 + + + +D +E+E L E + +V PHIA Sbjct: 245 IAAVNDGTLLGAAIDTYENEAAYFTNDWTNKDIDDKTLLELIEHERILVTPHIA 298
>LDHD_STAAN (P99116) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 73.9 bits (180), Expect = 3e-13 Identities = 54/174 (31%), Positives = 85/174 (48%), Gaps = 14/174 (8%) Frame = +2 Query: 26 LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPV 205 +K TV +IG GRIG+A A++ GF + +D Y + L+ FL Sbjct: 144 VKNMTVAIIGTGRIGAATAKIYA-GFGATITAYDAYPNKDLD--------FL-------- 186 Query: 206 TWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVAL 385 T+K S++E +++AD+ISLH +K +YHL + +KK A+LVNA+RG VI+ L Sbjct: 187 TYK--DSVKEAIKDADIISLHVPANKESYHLFDKAMFDHVKKGAILVNAARGAVINTPDL 244 Query: 386 VEHLKANPMFRVGLDVFEDEPYMKPG--------------LAEMKNAVVVPHIA 505 + + + +D +E+E L E + +V PHIA Sbjct: 245 IAAVNDGTLLGAAIDTYENEAAYFTNDWTNKDIDDKTLLELIEHERILVTPHIA 298
>LDHD_STAAM (P63940) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 73.9 bits (180), Expect = 3e-13 Identities = 54/174 (31%), Positives = 85/174 (48%), Gaps = 14/174 (8%) Frame = +2 Query: 26 LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPV 205 +K TV +IG GRIG+A A++ GF + +D Y + L+ FL Sbjct: 144 VKNMTVAIIGTGRIGAATAKIYA-GFGATITAYDAYPNKDLD--------FL-------- 186 Query: 206 TWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVAL 385 T+K S++E +++AD+ISLH +K +YHL + +KK A+LVNA+RG VI+ L Sbjct: 187 TYK--DSVKEAIKDADIISLHVPANKESYHLFDKAMFDHVKKGAILVNAARGAVINTPDL 244 Query: 386 VEHLKANPMFRVGLDVFEDEPYMKPG--------------LAEMKNAVVVPHIA 505 + + + +D +E+E L E + +V PHIA Sbjct: 245 IAAVNDGTLLGAAIDTYENEAAYFTNDWTNKDIDDKTLLELIEHERILVTPHIA 298
>LDHD_STAAC (Q5HD29) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 73.9 bits (180), Expect = 3e-13 Identities = 54/174 (31%), Positives = 85/174 (48%), Gaps = 14/174 (8%) Frame = +2 Query: 26 LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPV 205 +K TV +IG GRIG+A A++ GF + +D Y + L+ FL Sbjct: 144 VKNMTVAIIGTGRIGAATAKIYA-GFGATITAYDAYPNKDLD--------FL-------- 186 Query: 206 TWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVAL 385 T+K S++E +++AD+ISLH +K +YHL + +KK A+LVNA+RG VI+ L Sbjct: 187 TYK--DSVKEAIKDADIISLHVPANKESYHLFDKAMFDHVKKGAILVNAARGAVINTPDL 244 Query: 386 VEHLKANPMFRVGLDVFEDEPYMKPG--------------LAEMKNAVVVPHIA 505 + + + +D +E+E L E + +V PHIA Sbjct: 245 IAAVNDGTLLGAAIDTYENEAAYFTNDWTNKDIDDKTLLELIEHERILVTPHIA 298
>PTXD_PSEST (O69054) Phosphonate dehydrogenase (EC 1.20.1.1) (NAD-dependent| phosphite dehydrogenase) Length = 336 Score = 73.9 bits (180), Expect = 3e-13 Identities = 58/192 (30%), Positives = 89/192 (46%), Gaps = 8/192 (4%) Frame = +2 Query: 11 FVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKAN 190 F G L TVG++G G IG A A + +G+ L Y + + L Sbjct: 138 FYGTGLDNATVGILGMGAIGLAMADRL-QGWGATLQYHE--------------AKALDTQ 182 Query: 191 GEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVI 370 EQ + ++ + E+ +D I L L+ T HL+N E LA+++ A+LVN RG V+ Sbjct: 183 TEQRLGLRQVAC-SELFASSDFILLALPLNADTQHLVNAELLALVRPGALLVNPCRGSVV 241 Query: 371 DEVALVEHLKANPMFRVGLDVFEDEPYMK--------PGLAEMKNAVVVPHIASASKWTR 526 DE A++ L+ + DVFE E + + P L N + PHI SA + R Sbjct: 242 DEAAVLAALERGQLGGYAADVFEMEDWARADRPRLIDPALLAHPNTLFTPHIGSAVRAVR 301 Query: 527 EGMATLAALNVL 562 + AA N++ Sbjct: 302 LEIERCAAQNII 313
>PDXB_PSESM (Q884R9) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 380 Score = 73.6 bits (179), Expect = 4e-13 Identities = 57/168 (33%), Positives = 87/168 (51%), Gaps = 5/168 (2%) Frame = +2 Query: 26 LKGQTVGVIGAGRIGSAY-ARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQP 202 L+ +T GV+GAG++G A + G+K+ L+ QS FV Sbjct: 114 LRQRTYGVVGAGQVGGRLIAVLKALGWKV-LVCDPPRQSAEGGDFV-------------- 158 Query: 203 VTWKRASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVI 370 S++E+L+ DVISLH LDK+ T+HL++ RL +++ A L+NASRG V+ Sbjct: 159 -------SLDEILQRCDVISLHTPLDKSGQSPTWHLLDEARLRQLRQGAWLINASRGAVV 211 Query: 371 DEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 514 D AL + + + LDV+E EP + LA++ + PHIA S Sbjct: 212 DNRALHDVMLEREDLQAVLDVWEGEPQVNVALADL-CVIGTPHIAGYS 258
>PDXB_PSEPK (Q88L20) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 380 Score = 73.6 bits (179), Expect = 4e-13 Identities = 59/171 (34%), Positives = 85/171 (49%), Gaps = 5/171 (2%) Frame = +2 Query: 17 GNLLKGQTVGVIGAGRIGSAYARMMIE-GFKMNLIYFDLYQSTRLEKFVTAYGQFLKANG 193 G L + GV+GAG +G R++ G+K+ L+ L Q+ +V Sbjct: 111 GVALPERVYGVVGAGEVGGRLVRVLHGLGWKV-LVCDPLRQAAEGGDYV----------- 158 Query: 194 EQPVTWKRASSMEEVLREADVISLHPVLDK----TTYHLINPERLAMMKKEAVLVNASRG 361 S+E +L++ DVISLH L + T+HL+ +LA ++ A LVNASRG Sbjct: 159 ----------SLETILQQCDVISLHTPLQRGGQHPTWHLLGQAQLAQLRPGAWLVNASRG 208 Query: 362 PVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 514 PV+D VAL E L LDV+E EP + LA++ + PHIA S Sbjct: 209 PVVDNVALRELLLDREDVHAVLDVWEGEPQVDLQLADL-CTLATPHIAGYS 258
>PDXB_SHEON (Q8ECR2) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 376 Score = 73.6 bits (179), Expect = 4e-13 Identities = 55/167 (32%), Positives = 83/167 (49%), Gaps = 4/167 (2%) Frame = +2 Query: 26 LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPV 205 L+G+ VG++GAG GSA A+ + E F + ++ D + +A G+ Sbjct: 115 LRGKVVGIVGAGNTGSATAKCL-EAFGIKVLLNDPIK---------------EAEGDP-- 156 Query: 206 TWKRASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVID 373 + S+E +L+EAD+ISLH + +T T HL + RL +K L+N RG VID Sbjct: 157 --RDFVSLETLLQEADIISLHVPITRTGEHKTLHLFDEARLMSLKANIWLINCCRGDVID 214 Query: 374 EVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 514 AL++ + ++ LDV+E EP P L PHIA S Sbjct: 215 NQALIKVKQQRDDLKLVLDVWEGEPNPMPELVPFAE-FATPHIAGYS 260
>LDHD_LACPL (Q88VJ2) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH)| Length = 332 Score = 73.6 bits (179), Expect = 4e-13 Identities = 47/140 (33%), Positives = 75/140 (53%) Frame = +2 Query: 26 LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPV 205 L TVGVIG GRIG A A + +GF +I +D+Y++ LEK G ++ Sbjct: 143 LNTMTVGVIGTGRIGRA-AIDIFKGFGAKVIGYDVYRNAELEK----EGMYV-------- 189 Query: 206 TWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVAL 385 +++E+ +ADVI+LH K YH++N + + MK A ++N +RG +ID L Sbjct: 190 -----DTLDELYAQADVITLHVPALKDNYHMLNADAFSKMKDGAYILNFARGTLIDSEDL 244 Query: 386 VEHLKANPMFRVGLDVFEDE 445 ++ L + + LD +E E Sbjct: 245 IKALDSGKVAGAALDTYEYE 264
>SERA_BOVIN (Q5EAD2) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH)| Length = 532 Score = 73.6 bits (179), Expect = 4e-13 Identities = 50/169 (29%), Positives = 81/169 (47%) Frame = +2 Query: 11 FVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKAN 190 F+G L G+ +G++G GRIG A M + F M I +D S + + Sbjct: 137 FMGTELNGKVLGILGLGRIGREVATRM-QSFGMKTIGYDPIISPEVSA----------SF 185 Query: 191 GEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVI 370 G Q + +E++ D I++H L +T L+N A KK +VN +RG ++ Sbjct: 186 GVQQLP------LEQIWPLCDFITVHTPLLPSTTGLLNDSTFAQCKKGVCVVNCARGGIV 239 Query: 371 DEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASK 517 DE AL+ L++ LDVF +EP L +N + PH+ +++K Sbjct: 240 DEGALLRALQSGQCAGAALDVFTEEPPRDRALVNHENVISCPHLGASTK 288
>SERA_PONPY (Q5R7M2) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH)| Length = 532 Score = 73.2 bits (178), Expect = 5e-13 Identities = 51/169 (30%), Positives = 82/169 (48%) Frame = +2 Query: 11 FVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKAN 190 F+G L G+T+G++G GRIG A M + M I +D S + + Sbjct: 137 FMGTELNGKTLGILGLGRIGREVAIRM-QSLGMKTIGYDPIISPEVSA----------SF 185 Query: 191 GEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVI 370 G Q + +EE+ D I++H L +T L+N A KK +VN +RG ++ Sbjct: 186 GVQQLP------LEEIWPLCDFITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGGIV 239 Query: 371 DEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASK 517 DE AL+ L++ LDVF +EP L + +N + PH+ +++K Sbjct: 240 DEGALLRALQSGQCAGAALDVFTEEPPRGRALVDHENVISCPHLGASTK 288
>GRHPR_MOUSE (Q91Z53) Glyoxylate reductase/hydroxypyruvate reductase (EC| 1.1.1.79) Length = 328 Score = 72.8 bits (177), Expect = 6e-13 Identities = 63/195 (32%), Positives = 87/195 (44%), Gaps = 8/195 (4%) Frame = +2 Query: 2 PHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFL 181 P G L TVG++G GRIG A AR RL+ F Q Sbjct: 143 PLWMCGYGLSQSTVGIVGLGRIGQAIAR-------------------RLKPFGV---QRF 180 Query: 182 KANGEQPVTWKRASSMEEVL------READVISLHPVLDKTTYHLINPERLAMMKKEAVL 343 G QP + A E + E+D I + L T L + + MK A+ Sbjct: 181 LYTGRQPRPQEAAEFQAEFVPIAQLAAESDFIVVSCSLTPDTMGLCSKDFFQKMKNTAIF 240 Query: 344 VNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPG--LAEMKNAVVVPHIASASK 517 +N SRG V+++ L + L + + GLDV EP + P L +KN V++PHI SA+ Sbjct: 241 INISRGDVVNQEDLYQALASGQIAAAGLDVTTPEP-LPPSHPLLTLKNCVILPHIGSATY 299 Query: 518 WTREGMATLAALNVL 562 TR M+ LAA N+L Sbjct: 300 KTRNTMSLLAANNLL 314
>LDHD_STAES (Q8CN22) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 72.8 bits (177), Expect = 6e-13 Identities = 52/175 (29%), Positives = 85/175 (48%), Gaps = 15/175 (8%) Frame = +2 Query: 26 LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPV 205 +K TV +IG GRIG+A ++ GF ++ +D Y + L FL+ Sbjct: 144 VKNMTVAIIGTGRIGAATGKIYA-GFGARVVGYDAYPNHSLS--------FLEYK----- 189 Query: 206 TWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVAL 385 ++E+ +++AD+ISLH +K ++HL + +KK AVLVNA+RG VI+ L Sbjct: 190 -----ETVEDAIKDADIISLHVPANKDSFHLFDNNMFKNVKKGAVLVNAARGAVINTPDL 244 Query: 386 VEHLKANPMFRVGLDVFE---------------DEPYMKPGLAEMKNAVVVPHIA 505 +E + + +D +E D+P + L +N +V PHIA Sbjct: 245 IEAVNNGTLSGAAIDTYENEANYFTFDCSNQTIDDPILL-DLIRNENILVTPHIA 298
>LDHD_STAEQ (Q5HLA0) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 72.8 bits (177), Expect = 6e-13 Identities = 52/175 (29%), Positives = 85/175 (48%), Gaps = 15/175 (8%) Frame = +2 Query: 26 LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPV 205 +K TV +IG GRIG+A ++ GF ++ +D Y + L FL+ Sbjct: 144 VKNMTVAIIGTGRIGAATGKIYA-GFGARVVGYDAYPNHSLS--------FLEYK----- 189 Query: 206 TWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVAL 385 ++E+ +++AD+ISLH +K ++HL + +KK AVLVNA+RG VI+ L Sbjct: 190 -----ETVEDAIKDADIISLHVPANKDSFHLFDNNMFKNVKKGAVLVNAARGAVINTPDL 244 Query: 386 VEHLKANPMFRVGLDVFE---------------DEPYMKPGLAEMKNAVVVPHIA 505 +E + + +D +E D+P + L +N +V PHIA Sbjct: 245 IEAVNNGTLSGAAIDTYENEANYFTFDCSNQTIDDPILL-DLIRNENILVTPHIA 298
>DHD2_LACPA (P17584) D-2-hydroxyisocaproate dehydrogenase (EC 1.1.1.-)| (D-HICDH) Length = 333 Score = 72.0 bits (175), Expect = 1e-12 Identities = 56/180 (31%), Positives = 88/180 (48%), Gaps = 15/180 (8%) Frame = +2 Query: 11 FVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKAN 190 F+G L QTVGV+G G IG A + +GF +I +D Y Sbjct: 138 FIGKELGQQTVGVMGTGHIGQV-AIKLFKGFGAKVIAYDPYPM----------------K 180 Query: 191 GEQPVTWKRASSMEEVLREADVISLH-PVLDKTTYHLINPERLAMMKKEAVLVNASRGPV 367 G+ P S+E++ +++DVI LH P +++ T H+IN +MK A+++N +R + Sbjct: 181 GDHPDF--DYVSLEDLFKQSDVIDLHVPGIEQNT-HIINEAAFNLMKPGAIVINTARPNL 237 Query: 368 IDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAE--------------MKNAVVVPHIA 505 ID A++ +LK+ + VG+D +E E LA+ M N V+ PHIA Sbjct: 238 IDTQAMLSNLKSGKLAGVGIDTYEYETEDLLNLAKHGSFKDPLWDELLGMPNVVLSPHIA 297
>VANH_ENTFA (Q47748) D-specific alpha-keto acid dehydrogenase (EC 1.1.1.-)| (Vancomycin B-type resistance protein vanHB) Length = 323 Score = 71.2 bits (173), Expect = 2e-12 Identities = 52/178 (29%), Positives = 79/178 (44%), Gaps = 15/178 (8%) Frame = +2 Query: 17 GNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGE 196 G L+ TVGVIG G IG A + + GF ++ +D K Y Q Sbjct: 142 GKELRDMTVGVIGTGHIGQAVVKRL-RGFGCRVLAYD-----NSRKIEADYVQ------- 188 Query: 197 QPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDE 376 ++E+L+ +D+++LH L T HLI ++ MK+ A L+N RG ++D Sbjct: 189 ----------LDELLKNSDIVTLHVPLCADTRHLIGQRQIGEMKQGAFLINTGRGALVDT 238 Query: 377 VALVEHLKANPMFRVGLDVFE---------------DEPYMKPGLAEMKNAVVVPHIA 505 +LVE L + + LDV E D P++ L M N ++ PH A Sbjct: 239 GSLVEALGSGKLGGAALDVLEGEDQFVYTDCSQKVLDHPFLSQ-LLRMPNVIITPHTA 295
>PDXB_YERPS (Q668W7) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 375 Score = 71.2 bits (173), Expect = 2e-12 Identities = 59/180 (32%), Positives = 89/180 (49%), Gaps = 6/180 (3%) Frame = +2 Query: 17 GNLLKGQTVGVIGAGRIGSAY-ARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANG 193 G L+ +TVG+IG G +GS AR+ G + L R ++ G Sbjct: 111 GFQLRDKTVGIIGVGNVGSRLNARLQALGVRTLLC-----DPPRADR------------G 153 Query: 194 EQPVTWKRASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRG 361 + W +E+++READV++ H L+KT + H+ + E LA + +L+NA RG Sbjct: 154 DNEAFWP----LEKLVREADVLTFHTPLNKTGAYQSLHMADDELLAALPDGRILINACRG 209 Query: 362 PVIDEVALVEHLKANPMFRVGLDVFEDEPYMK-PGLAEMKNAVVVPHIASASKWTREGMA 538 V+D AL+ L+ V LDV+E EP + P LA + + PHIA +T EG A Sbjct: 210 AVVDNAALLRALEKGKKLSVVLDVWEPEPDLSLPLLARVD--IGTPHIAG---YTLEGKA 264
>PDXB_YERPE (Q8D0U3) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 375 Score = 71.2 bits (173), Expect = 2e-12 Identities = 59/180 (32%), Positives = 89/180 (49%), Gaps = 6/180 (3%) Frame = +2 Query: 17 GNLLKGQTVGVIGAGRIGSAY-ARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANG 193 G L+ +TVG+IG G +GS AR+ G + L R ++ G Sbjct: 111 GFQLRDKTVGIIGVGNVGSRLNARLQALGVRTLLC-----DPPRADR------------G 153 Query: 194 EQPVTWKRASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRG 361 + W +E+++READV++ H L+KT + H+ + E LA + +L+NA RG Sbjct: 154 DNEAFWP----LEKLVREADVLTFHTPLNKTGAYQSLHMADDELLAALPDGRILINACRG 209 Query: 362 PVIDEVALVEHLKANPMFRVGLDVFEDEPYMK-PGLAEMKNAVVVPHIASASKWTREGMA 538 V+D AL+ L+ V LDV+E EP + P LA + + PHIA +T EG A Sbjct: 210 AVVDNAALLRALEKGKKLSVVLDVWEPEPDLSLPLLARVD--IGTPHIAG---YTLEGKA 264
>PDXB_SALTY (P60802) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 378 Score = 70.9 bits (172), Expect = 2e-12 Identities = 54/178 (30%), Positives = 88/178 (49%), Gaps = 4/178 (2%) Frame = +2 Query: 17 GNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGE 196 G L+ +T+G++G G +GS + +E + + D ++ R ++ G F Sbjct: 111 GFSLRDRTIGIVGVGNVGSRL-QTRLEALGIRTLLCDPPRAARGDE-----GDF------ 158 Query: 197 QPVTWKRASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGP 364 +++E+++EADV++ H L K T HL + + +K A+L+NA RGP Sbjct: 159 --------RTLDELVQEADVLTFHTPLYKDGPYKTLHLADETLIRRLKPGAILINACRGP 210 Query: 365 VIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 538 V+D AL+ L A V LDV+E EP + L E + + HIA +T EG A Sbjct: 211 VVDNAALLARLNAGQPLSVVLDVWEGEPDLNVALLEAVD-IGTSHIAG---YTLEGKA 264
>PDXB_SALTI (P60801) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 378 Score = 70.9 bits (172), Expect = 2e-12 Identities = 54/178 (30%), Positives = 88/178 (49%), Gaps = 4/178 (2%) Frame = +2 Query: 17 GNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGE 196 G L+ +T+G++G G +GS + +E + + D ++ R ++ G F Sbjct: 111 GFSLRDRTIGIVGVGNVGSRL-QTRLEALGIRTLLCDPPRAARGDE-----GDF------ 158 Query: 197 QPVTWKRASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGP 364 +++E+++EADV++ H L K T HL + + +K A+L+NA RGP Sbjct: 159 --------RTLDELVQEADVLTFHTPLYKDGPYKTLHLADETLIRRLKPGAILINACRGP 210 Query: 365 VIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 538 V+D AL+ L A V LDV+E EP + L E + + HIA +T EG A Sbjct: 211 VVDNAALLARLNAGQPLSVVLDVWEGEPDLNVALLEAVD-IGTSHIAG---YTLEGKA 264
>FDH1_ORYSA (Q9SXP2) Formate dehydrogenase 1, mitochondrial precursor (EC| 1.2.1.2) (NAD-dependent formate dehydrogenase 1) (FDH 1) Length = 376 Score = 70.5 bits (171), Expect = 3e-12 Identities = 51/165 (30%), Positives = 82/165 (49%), Gaps = 2/165 (1%) Frame = +2 Query: 26 LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFD-LYQSTRLEKFVTAYGQFLKANGEQP 202 L+G+TVG +GAGRIG + + + F NL+Y D L LEK + A Sbjct: 187 LEGKTVGTVGAGRIGRLLLQRL-KPFNCNLLYHDRLKIDPELEKEIGA------------ 233 Query: 203 VTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVA 382 K ++ +L + DVI ++ L + T + N ER+A MKK ++VN +RG ++D A Sbjct: 234 ---KYEEDLDAMLPKCDVIVINTPLTEKTRGMFNKERIAKMKKGVIIVNNARGAIMDTQA 290 Query: 383 LVEHLKANPMFRVGLDVFEDEPYMKP-GLAEMKNAVVVPHIASAS 514 + + + + G DV+ +P K M N + PHI+ + Sbjct: 291 VADACSSGQVAGYGGDVWFPQPAPKDHPWRYMPNHAMTPHISGTT 335
>LDHD_PEDAC (Q59642) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 331 Score = 70.5 bits (171), Expect = 3e-12 Identities = 53/195 (27%), Positives = 94/195 (48%), Gaps = 14/195 (7%) Frame = +2 Query: 14 VGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANG 193 +G L TVGVIG GRIG A A + + F +I +D++++ LEK G ++ Sbjct: 138 IGLELNQMTVGVIGTGRIGRA-AIDIFKPFGAKVIAYDVFRNPALEK----EGMYV---- 188 Query: 194 EQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVID 373 ++EE+ ++A+VI+LH K YH+++ + M+ ++N +RG ++D Sbjct: 189 ---------DTLEELYQQANVITLHVPALKDNYHMLDEKAFGQMQDGTFILNFARGTLVD 239 Query: 374 EVALVEHLKANPMFRVGLDVFE-----------DEPYMKP---GLAEMKNAVVVPHIASA 511 AL++ L + + LD +E D+P P L +N ++ PH A Sbjct: 240 TPALLKALDSGKVAGAALDTYENEVGIFDVDHGDQPIDDPVFNDLMSRRNVMITPHAAFY 299 Query: 512 SKWTREGMATLAALN 556 ++ + M +A N Sbjct: 300 TRPAVKNMVQIALDN 314
>SERA_SHIFL (P0A9T3) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 409 Score = 70.1 bits (170), Expect = 4e-12 Identities = 50/186 (26%), Positives = 91/186 (48%), Gaps = 6/186 (3%) Frame = +2 Query: 29 KGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVT 208 +G+ +G+IG G IG+ ++ E M + ++D+ L N Q Sbjct: 149 RGKKLGIIGYGHIGTQLG-ILAESLGMYVYFYDIENKLPL------------GNATQ--- 192 Query: 209 WKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALV 388 + ++L +DV+SLH + +T +++ + +++MK ++L+NASRG V+D AL Sbjct: 193 ---VQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALC 249 Query: 389 EHLKANPMFRVGLDVFEDE------PYMKPGLAEMKNAVVVPHIASASKWTREGMATLAA 550 + L + + +DVF E P+ P L E N ++ PHI +++ +E + Sbjct: 250 DALASKHLAGAAIDVFPTEPATNSDPFTSP-LCEFDNVLLTPHIGGSTQEAQENI----G 304 Query: 551 LNVLGK 568 L V GK Sbjct: 305 LEVAGK 310
>SERA_ECOLI (P0A9T0) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 409 Score = 70.1 bits (170), Expect = 4e-12 Identities = 50/186 (26%), Positives = 91/186 (48%), Gaps = 6/186 (3%) Frame = +2 Query: 29 KGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVT 208 +G+ +G+IG G IG+ ++ E M + ++D+ L N Q Sbjct: 149 RGKKLGIIGYGHIGTQLG-ILAESLGMYVYFYDIENKLPL------------GNATQ--- 192 Query: 209 WKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALV 388 + ++L +DV+SLH + +T +++ + +++MK ++L+NASRG V+D AL Sbjct: 193 ---VQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALC 249 Query: 389 EHLKANPMFRVGLDVFEDE------PYMKPGLAEMKNAVVVPHIASASKWTREGMATLAA 550 + L + + +DVF E P+ P L E N ++ PHI +++ +E + Sbjct: 250 DALASKHLAGAAIDVFPTEPATNSDPFTSP-LCEFDNVLLTPHIGGSTQEAQENI----G 304 Query: 551 LNVLGK 568 L V GK Sbjct: 305 LEVAGK 310
>SERA_ECOL6 (P0A9T1) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 409 Score = 70.1 bits (170), Expect = 4e-12 Identities = 50/186 (26%), Positives = 91/186 (48%), Gaps = 6/186 (3%) Frame = +2 Query: 29 KGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVT 208 +G+ +G+IG G IG+ ++ E M + ++D+ L N Q Sbjct: 149 RGKKLGIIGYGHIGTQLG-ILAESLGMYVYFYDIENKLPL------------GNATQ--- 192 Query: 209 WKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALV 388 + ++L +DV+SLH + +T +++ + +++MK ++L+NASRG V+D AL Sbjct: 193 ---VQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALC 249 Query: 389 EHLKANPMFRVGLDVFEDE------PYMKPGLAEMKNAVVVPHIASASKWTREGMATLAA 550 + L + + +DVF E P+ P L E N ++ PHI +++ +E + Sbjct: 250 DALASKHLAGAAIDVFPTEPATNSDPFTSP-LCEFDNVLLTPHIGGSTQEAQENI----G 304 Query: 551 LNVLGK 568 L V GK Sbjct: 305 LEVAGK 310
>SERA_ECO57 (P0A9T2) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 409 Score = 70.1 bits (170), Expect = 4e-12 Identities = 50/186 (26%), Positives = 91/186 (48%), Gaps = 6/186 (3%) Frame = +2 Query: 29 KGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVT 208 +G+ +G+IG G IG+ ++ E M + ++D+ L N Q Sbjct: 149 RGKKLGIIGYGHIGTQLG-ILAESLGMYVYFYDIENKLPL------------GNATQ--- 192 Query: 209 WKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALV 388 + ++L +DV+SLH + +T +++ + +++MK ++L+NASRG V+D AL Sbjct: 193 ---VQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALC 249 Query: 389 EHLKANPMFRVGLDVFEDE------PYMKPGLAEMKNAVVVPHIASASKWTREGMATLAA 550 + L + + +DVF E P+ P L E N ++ PHI +++ +E + Sbjct: 250 DALASKHLAGAAIDVFPTEPATNSDPFTSP-LCEFDNVLLTPHIGGSTQEAQENI----G 304 Query: 551 LNVLGK 568 L V GK Sbjct: 305 LEVAGK 310
>LDHD_STRA5 (Q8E0N5) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 70.1 bits (170), Expect = 4e-12 Identities = 45/147 (30%), Positives = 74/147 (50%), Gaps = 1/147 (0%) Frame = +2 Query: 17 GNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGE 196 G +L TV +IG GRIG A A++ +GF +I +D+Y + + + Sbjct: 140 GRVLGNMTVAIIGTGRIGLATAKIF-KGFGCRVIGYDIYHNPMADGIL------------ 186 Query: 197 QPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDE 376 + +S+EE + EAD++SLH HL N + KK A+L+N +RG +++ Sbjct: 187 -----EYVNSVEEAVEEADLVSLHMPPTAENTHLFNLDMFKQFKKGAILMNMARGALVET 241 Query: 377 VALVEHLKANPMFRVGLDVFEDE-PYM 454 L+E L + G+D +E E PY+ Sbjct: 242 KDLLEALDQGLLEGAGIDTYEFEGPYI 268
>LDHD_LACPE (P26298) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 332 Score = 70.1 bits (170), Expect = 4e-12 Identities = 46/140 (32%), Positives = 74/140 (52%) Frame = +2 Query: 26 LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPV 205 L TVGVIG GRIG A A + +GF +I +D+Y++ LEK G ++ Sbjct: 143 LNTMTVGVIGTGRIGRA-AIDIFKGFGAKVIGYDVYRNAELEK----EGMYV-------- 189 Query: 206 TWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVAL 385 +++E+ +ADVI+LH K YH++N + + MK A ++N +RG +ID L Sbjct: 190 -----DTLDELYAQADVITLHVPALKDNYHMLNADAFSKMKDGAYILNFARGTLIDSEDL 244 Query: 386 VEHLKANPMFRVGLDVFEDE 445 ++ L + + L +E E Sbjct: 245 IKALDSGKVAGAALVTYEYE 264
>VANH_ENTFC (Q05709) D-specific alpha-keto acid dehydrogenase (EC 1.1.1.-)| (Vancomycin resistance protein vanH) Length = 322 Score = 70.1 bits (170), Expect = 4e-12 Identities = 50/177 (28%), Positives = 82/177 (46%), Gaps = 14/177 (7%) Frame = +2 Query: 17 GNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGE 196 G +L TVGV+G G+IG A + GF ++ + +S + Y F Sbjct: 141 GKVLSDMTVGVVGTGQIGKAVIERL-RGFGCKVLAYSRSRSIEVN-----YVPF------ 188 Query: 197 QPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDE 376 +E+L+ +D+++LH L+ T+++I+ E++ MK+ A L+N RGP++D Sbjct: 189 -----------DELLQNSDIVTLHVPLNTDTHYIISHEQIQRMKQGAFLINTGRGPLVDT 237 Query: 377 VALVEHLKANPMFRVGLDVFEDEP-------YMKP-------GLAEMKNAVVVPHIA 505 LV+ L+ + LDV E E KP L M N ++ PH A Sbjct: 238 YELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQFLLKLQRMPNVIITPHTA 294
>FDH_NEUCR (Q07103) Formate dehydrogenase (EC 1.2.1.2) (NAD-dependent formate| dehydrogenase) (FDH) Length = 375 Score = 69.3 bits (168), Expect = 7e-12 Identities = 51/169 (30%), Positives = 84/169 (49%), Gaps = 6/169 (3%) Frame = +2 Query: 26 LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPV 205 L+G+ VG +G GRIG R + L+Y+D YQ EK E + Sbjct: 163 LEGKVVGTVGVGRIGERVLRRLKPFDCKELLYYD-YQPLSAEK-------------EAEI 208 Query: 206 TWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVAL 385 +R + +EE+L + DV++++ L + T L N E ++ MKK + LVN +RG ++ + + Sbjct: 209 GCRRVADLEEMLAQCDVVTINCPLHEKTQGLFNKELISKMKKGSWLVNTARGAIVVKEDV 268 Query: 386 VEHLKANPMFRVGLDVFEDEPYMKP-GLAEMKNA-----VVVPHIASAS 514 E LK+ + G DV+ +P + L KN +VPH++ S Sbjct: 269 AEALKSGHLRGYGGDVWFPQPAPQDHPLRYAKNPFGGGNAMVPHMSGTS 317
>YGDH_SCHPO (O94574) Putative 2-hydroxyacid dehydrogenase C1773.17c (EC| 1.-.-.-) Length = 340 Score = 68.9 bits (167), Expect = 9e-12 Identities = 46/164 (28%), Positives = 79/164 (48%) Frame = +2 Query: 32 GQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTW 211 G+ VG+IG G IG ++A+ ++ ++Y + RLE E+ Sbjct: 159 GKRVGIIGMGAIGKSFAQKILP-LGCEIVY---HNRNRLEA------------EEEKRLG 202 Query: 212 KRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVE 391 S +E+L +DVIS++ L T+ LI+ + MK ++N +RG +I+E A ++ Sbjct: 203 ASFVSFDELLSSSDVISINCPLTPATHDLISTKEFEKMKDGVYIINTARGAIINEDAFIK 262 Query: 392 HLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWT 523 +K+ + R GLDVF +EP E + PH + +T Sbjct: 263 AIKSGKVARAGLDVFLNEPTPNKFWLECDKVTIQPHCGVYTNFT 306
>LDHD_STRA3 (Q8E6A9) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 68.6 bits (166), Expect = 1e-11 Identities = 44/147 (29%), Positives = 74/147 (50%), Gaps = 1/147 (0%) Frame = +2 Query: 17 GNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGE 196 G +L TV +IG GRIG A A++ +GF +I +D+Y + + + Sbjct: 140 GRVLGNMTVAIIGTGRIGLATAKIF-KGFGCRVIGYDIYHNPMADGIL------------ 186 Query: 197 QPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDE 376 + +S+EE + +AD++SLH HL N + KK A+L+N +RG +++ Sbjct: 187 -----EYVNSVEEAVEKADLVSLHMPPTAENTHLFNLDMFKQFKKGAILMNMARGALVET 241 Query: 377 VALVEHLKANPMFRVGLDVFEDE-PYM 454 L+E L + G+D +E E PY+ Sbjct: 242 KDLLEALDQGLLEGAGIDTYEFEGPYI 268
>FDH_HORVU (Q9ZRI8) Formate dehydrogenase, mitochondrial precursor (EC| 1.2.1.2) (NAD-dependent formate dehydrogenase) (FDH) Length = 377 Score = 67.8 bits (164), Expect = 2e-11 Identities = 48/165 (29%), Positives = 82/165 (49%), Gaps = 2/165 (1%) Frame = +2 Query: 26 LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQ-STRLEKFVTAYGQFLKANGEQP 202 L+G+TVG +GAGR G + + + F NL+Y D Q + LEK + A Sbjct: 188 LEGKTVGTVGAGRYGRLLLQRL-KPFNCNLLYHDRLQINPELEKEIGA------------ 234 Query: 203 VTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVA 382 K ++ +L + DV+ ++ L + T + N E++A MKK ++VN +RG ++D A Sbjct: 235 ---KFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNARGAIMDTQA 291 Query: 383 LVEHLKANPMFRVGLDVFEDEPYMKP-GLAEMKNAVVVPHIASAS 514 + + + + G DV+ +P K M N + PHI+ + Sbjct: 292 VADACSSGHIAGYGGDVWFPQPAPKDHPWRYMPNHAMTPHISGTT 336
>PDXB_SHEVI (Q56733) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| (Fragment) Length = 274 Score = 67.8 bits (164), Expect = 2e-11 Identities = 52/167 (31%), Positives = 80/167 (47%), Gaps = 4/167 (2%) Frame = +2 Query: 26 LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPV 205 LK +TVG++GAG GSA A+ + L++ + Q + F+ Sbjct: 2 LKDKTVGIVGAGNTGSAVAKCLQAYGVTVLLHDPVIQDSDPRDFI--------------- 46 Query: 206 TWKRASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVID 373 S++E++ DVISLH + KT T++L + RL +K L+N RG VID Sbjct: 47 ------SLDELIARCDVISLHVPIIKTGEHKTWYLFDETRLNSLKPGTWLLNCCRGEVID 100 Query: 374 EVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 514 AL++ + P ++ LDV+E EP L + + PHIA S Sbjct: 101 NRALIKVKQQRPDIKLVLDVWEGEPNPMHELIPLVE-LATPHIAGYS 146
>PDXB_SHESP (Q56731) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| (Fragment) Length = 274 Score = 67.0 bits (162), Expect = 4e-11 Identities = 52/167 (31%), Positives = 80/167 (47%), Gaps = 4/167 (2%) Frame = +2 Query: 26 LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPV 205 LK +TVG++GAG GSA A+ + L++ + Q + F+ Sbjct: 2 LKDKTVGIVGAGNTGSAVAKCLQAYGVTVLLHDPVIQDSDPRDFI--------------- 46 Query: 206 TWKRASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVID 373 S++E++ DVISLH + KT T++L + RL +K+ L+N RG VID Sbjct: 47 ------SLDELIACCDVISLHVPITKTGEHKTWYLFDEARLNSLKQGTWLLNCCRGEVID 100 Query: 374 EVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 514 AL++ P ++ LDV+E EP L + + PHIA S Sbjct: 101 NQALIKVKLERPDIKLVLDVWEGEPNPMHELIPLVE-LATPHIAGYS 146
>FDH_SOLTU (Q07511) Formate dehydrogenase, mitochondrial precursor (EC| 1.2.1.2) (NAD-dependent formate dehydrogenase) (FDH) Length = 381 Score = 66.2 bits (160), Expect = 6e-11 Identities = 46/165 (27%), Positives = 83/165 (50%), Gaps = 2/165 (1%) Frame = +2 Query: 26 LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFD-LYQSTRLEKFVTAYGQFLKANGEQP 202 L+G+TVG +GAGRIG + + + F NL+Y D L + LE + A Sbjct: 192 LEGKTVGTVGAGRIGRLLLQRL-KPFNCNLLYHDRLKMDSELENQIGA------------ 238 Query: 203 VTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVA 382 K ++++L + D++ ++ L + T + + ER+A +KK ++VN +RG ++D A Sbjct: 239 ---KFEEDLDKMLSKCDIVVINTPLTEKTKGMFDKERIAKLKKGVLIVNNARGAIMDTQA 295 Query: 383 LVEHLKANPMFRVGLDVFEDEPYMKP-GLAEMKNAVVVPHIASAS 514 +V+ + + DV+ +P K M N + PHI+ + Sbjct: 296 VVDACNSGHIAGYSGDVWYPQPAPKDHPWRYMPNQAMTPHISGTT 340
>PDXB_BACTN (Q8A2E4) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 348 Score = 65.9 bits (159), Expect = 8e-11 Identities = 52/163 (31%), Positives = 83/163 (50%), Gaps = 4/163 (2%) Frame = +2 Query: 38 TVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKR 217 T+G+IG G +GS A++ + F M ++ DL R EK E +T+ Sbjct: 119 TIGIIGVGNVGSKVAKVA-QDFGMRVLLNDL---PREEK-------------EGNITF-- 159 Query: 218 ASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVAL 385 +S+E++ E D+I+ H L K TYHL + ++++ V++N SRG VI+ AL Sbjct: 160 -TSLEKIAEECDIITFHVPLYKEGKYKTYHLADGNFFRSLQRKPVVINTSRGEVIETNAL 218 Query: 386 VEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 514 +E + + +DV+E EP + L E K + PHIA S Sbjct: 219 LEAINNGIISDAVIDVWEHEPEINRELLE-KVLIGTPHIAGYS 260
>YPRB2_CORML (P0C1E9) Hypothetical protein in proB 3'region (EC 1.-.-.-)| Length = 304 Score = 65.9 bits (159), Expect = 8e-11 Identities = 43/111 (38%), Positives = 55/111 (49%), Gaps = 1/111 (0%) Frame = +2 Query: 230 EEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANP 409 E V EADV L L TY ++N E L MK AVLVN RGP+I+ LV+ L Sbjct: 175 EHVWAEADVFVLILPLTDATYQIVNAETLGKMKPSAVLVNVGRGPLINTDDLVDALNNGT 234 Query: 410 MFRVGLDVFEDEPYM-KPGLAEMKNAVVVPHIASASKWTREGMATLAALNV 559 + LDV + EP L EM N V+ PH A+ ++ R L N+ Sbjct: 235 IAGAALDVTDPEPLPDSHPLWEMDNVVITPHTANTNERIRALTGELTLRNI 285
>PDXB_WIGBR (Q8D2P6) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 378 Score = 65.5 bits (158), Expect = 1e-10 Identities = 53/170 (31%), Positives = 83/170 (48%), Gaps = 5/170 (2%) Frame = +2 Query: 20 NLLKGQTVGVIGAGRIGSAYARMMIE-GFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGE 196 +LLK +TVG++G G IG + + G K L L + + Sbjct: 113 SLLK-KTVGIVGFGNIGKCLNKKLSAIGVKTILCDPILEEKNNI---------------- 155 Query: 197 QPVTWKRASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGP 364 + S+ E+++ +D+I+LH L + T+HLIN + L +K +L+N SRG Sbjct: 156 ------KLKSLNEIVQNSDIITLHVPLTYSGKYPTWHLINKKILLDLKDNCILINTSRGS 209 Query: 365 VIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 514 VID +L+ LK RV LDV+E+EP + L + + + PHIA S Sbjct: 210 VIDNNSLLNILKEGKPIRVVLDVWENEPLICSKLLSLID-IGTPHIAGHS 258
>FDH2_ORYSA (Q67U69) Formate dehydrogenase 2, mitochondrial precursor (EC| 1.2.1.2) (NAD-dependent formate dehydrogenase 2) (FDH 2) Length = 378 Score = 65.1 bits (157), Expect = 1e-10 Identities = 48/165 (29%), Positives = 80/165 (48%), Gaps = 2/165 (1%) Frame = +2 Query: 26 LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQ-STRLEKFVTAYGQFLKANGEQP 202 L+G+TVG +GAGRIG + + + F NL+Y D + LEK + A Sbjct: 189 LEGKTVGTVGAGRIGRLLLQRL-KPFNCNLMYHDRVKIDPELEKEIGA------------ 235 Query: 203 VTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVA 382 K ++ +L + DV+ ++ L + T + N ER+A MKK +VN +RG ++D A Sbjct: 236 ---KYEEDLDAMLPKCDVVVINMPLTEKTRGMFNKERIAKMKKGVTIVNNARGAIMDTQA 292 Query: 383 LVEHLKANPMFRVGLDVFEDEPYMKP-GLAEMKNAVVVPHIASAS 514 + + + + G DV+ +P K M N + PH + + Sbjct: 293 VADACASGHVAGYGGDVWFPQPAPKDHPWRYMPNHAMTPHCSGTT 337
>Y2355_CORGL (P0C1E8) Hypothetical protein Cgl2355/cg2587 (EC 1.-.-.-)| Length = 304 Score = 64.7 bits (156), Expect = 2e-10 Identities = 42/111 (37%), Positives = 55/111 (49%), Gaps = 1/111 (0%) Frame = +2 Query: 230 EEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANP 409 E V EADV L L TY ++N E L MK AV+VN RGP+I+ LV+ L Sbjct: 175 EHVWAEADVFVLILPLTDATYQIVNAETLGKMKPSAVVVNVGRGPLINTDDLVDALNNGT 234 Query: 410 MFRVGLDVFEDEPYM-KPGLAEMKNAVVVPHIASASKWTREGMATLAALNV 559 + LDV + EP L EM N V+ PH A+ ++ R L N+ Sbjct: 235 IAGAALDVTDPEPLPDSHPLWEMDNVVITPHTANTNERIRALTGELTLRNI 285
>FDH_ARATH (Q9S7E4) Formate dehydrogenase, mitochondrial precursor (EC| 1.2.1.2) (NAD-dependent formate dehydrogenase) (FDH) Length = 384 Score = 64.3 bits (155), Expect = 2e-10 Identities = 46/165 (27%), Positives = 82/165 (49%), Gaps = 2/165 (1%) Frame = +2 Query: 26 LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFD-LYQSTRLEKFVTAYGQFLKANGEQP 202 L+G+T+G +GAGRIG + + + F NL+Y D L + LEK A Sbjct: 195 LEGKTIGTVGAGRIGKLLLQRL-KPFGCNLLYHDRLQMAPELEKETGA------------ 241 Query: 203 VTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVA 382 K + E+L + DVI ++ L + T + N E + +KK ++VN +RG +++ A Sbjct: 242 ---KFVEDLNEMLPKCDVIVINMPLTEKTRGMFNKELIGKLKKGVLIVNNARGAIMERQA 298 Query: 383 LVEHLKANPMFRVGLDVFEDEPYMKP-GLAEMKNAVVVPHIASAS 514 +V+ +++ + DV++ +P K M N + PH + + Sbjct: 299 VVDAVESGHIGGYSGDVWDPQPAPKDHPWRYMPNQAMTPHTSGTT 343
>PDXB_ERWCT (Q6D2N5) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 378 Score = 63.2 bits (152), Expect = 5e-10 Identities = 56/179 (31%), Positives = 85/179 (47%), Gaps = 5/179 (2%) Frame = +2 Query: 17 GNLLKGQTVGVIGAGRIGSAY-ARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANG 193 G L+ +TVG++G G +G R+ G K L D ++ R + G FL Sbjct: 111 GFQLRDKTVGIVGVGNVGRRLDTRLKAWGVKTLLC--DPPRADRGDA-----GDFL---- 159 Query: 194 EQPVTWKRASSMEEVLREADVISLHPVL----DKTTYHLINPERLAMMKKEAVLVNASRG 361 S+E ++R+AD+++LH L T+HL++ L +L+NA RG Sbjct: 160 ----------SLETLVRDADILTLHTPLYLDGPYRTHHLVDATVLNAFADGRILINACRG 209 Query: 362 PVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 538 PV+D AL+E L+ V LDV+E EP + L + + HIA +T EG A Sbjct: 210 PVVDNAALLEALQQGKKLSVILDVWEPEPGLSTDLLARVD-IGTAHIAG---YTLEGKA 264
>PDXB_ECOL6 (Q8FFH2) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 378 Score = 63.2 bits (152), Expect = 5e-10 Identities = 52/178 (29%), Positives = 85/178 (47%), Gaps = 4/178 (2%) Frame = +2 Query: 17 GNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGE 196 G L +TVG++G G +G + +E + + D ++ R ++ G F Sbjct: 111 GFSLHERTVGIVGVGNVGRRL-QARLEALGIKTLLCDPPRADRGDE-----GDF------ 158 Query: 197 QPVTWKRASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGP 364 S++E+++ AD+++ H L K T HL + + + +K A+L+NA RG Sbjct: 159 --------RSLDELVQHADILTFHTPLFKDGPYKTLHLADEKLIRSLKPGAILINACRGA 210 Query: 365 VIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 538 V+D AL+ L V LDV+E EP + L + K + PHIA +T EG A Sbjct: 211 VVDNTALLTCLNEGQKLSVVLDVWEGEPELNVELLK-KVDIGTPHIAG---YTLEGKA 264
>PDXB_PHOPR (Q6LNU2) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 391 Score = 63.2 bits (152), Expect = 5e-10 Identities = 49/166 (29%), Positives = 80/166 (48%), Gaps = 9/166 (5%) Frame = +2 Query: 35 QTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWK 214 +T+G+IGAG +GS Y ++ + + D + EQ + Sbjct: 118 KTIGIIGAGNVGS-YLAQCLDALGIPYLLNDPIK-------------------EQEGDTR 157 Query: 215 RASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVA 382 + S+E + + DVI++H + K T+HLIN + ++ +A+L+NA+RGPV D A Sbjct: 158 QFHSLEAIKAQCDVITVHTPITKDGEYPTHHLINEAFIDALQPDAILINAARGPVTDNQA 217 Query: 383 LVEHLKAN-----PMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIA 505 L + L+ + LDVFE EP++ L + A PHIA Sbjct: 218 LKKALQLSQSGLGKKLTAVLDVFEFEPHVDLELLPLL-AFATPHIA 262
>PDXB_SHIFL (Q83QR1) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 378 Score = 62.8 bits (151), Expect = 7e-10 Identities = 52/178 (29%), Positives = 84/178 (47%), Gaps = 4/178 (2%) Frame = +2 Query: 17 GNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGE 196 G L +TVG++G G +G + +E + + D ++ R ++ G F Sbjct: 111 GFSLHDRTVGIVGVGNVGRRL-QARLEALGIKTLLCDPPRADRGDE-----GDF------ 158 Query: 197 QPVTWKRASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGP 364 S++E+++ AD+++ H L K T HL + + + +K A+L+NA RG Sbjct: 159 --------RSLDELVQRADILTFHTPLFKDGPYKTLHLADEKLIRSLKPGAILINACRGA 210 Query: 365 VIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 538 V+D AL+ L V LDV+E EP + L K + PHIA +T EG A Sbjct: 211 VVDNTALLTCLNEGQKLSVVLDVWEGEPELNVELL-TKVDIGTPHIAG---YTLEGKA 264
>PDXB_BLOFL (Q7VRU9) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 372 Score = 62.0 bits (149), Expect = 1e-09 Identities = 49/168 (29%), Positives = 88/168 (52%), Gaps = 5/168 (2%) Frame = +2 Query: 26 LKGQTVGVIGAGRIGSA-YARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQP 202 L+ +TVG+IG G IG+ Y R+ G ++ + +D Y+S K + ++ Sbjct: 114 LRDKTVGIIGVGNIGNLLYQRLNSLG--VHTLLYDPYKS--------------KCDTDR- 156 Query: 203 VTWKRASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVI 370 ++WK S++ ++ ++D+++LH L T T+H+IN + L + ++L+N SRG V+ Sbjct: 157 MSWK---SLDILVSKSDILTLHVPLTYTGAYPTWHMINKDILDALPSNSILINTSRGAVV 213 Query: 371 DEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 514 + L+ L+ V LDV+E EP + L + + HIA S Sbjct: 214 NNDDLLAILRCGKKINVILDVWESEPKLSLPLLSYVD-IGTAHIAGYS 260
>PDXB_ECOLI (P05459) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 378 Score = 60.1 bits (144), Expect = 4e-09 Identities = 51/178 (28%), Positives = 84/178 (47%), Gaps = 4/178 (2%) Frame = +2 Query: 17 GNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGE 196 G L +TVG++G G +G + +E + + D ++ R ++ G F Sbjct: 111 GFSLYDRTVGIVGVGNVGRRL-QARLEALGIKTLLCDPPRADRGDE-----GDF------ 158 Query: 197 QPVTWKRASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGP 364 S++E+++ AD+++ H L K T HL + + + +K A+L+NA RG Sbjct: 159 --------RSLDELVQRADILTFHTPLFKDGPYKTLHLADEKLIRSLKPGAILINACRGA 210 Query: 365 VIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 538 V+D AL+ L V LDV+E EP + L + K + HIA +T EG A Sbjct: 211 VVDNTALLTCLNEGQKLSVVLDVWEGEPELNVELLK-KVDIGTSHIAG---YTLEGKA 264
>PDXB_ECO57 (Q8XCR0) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 378 Score = 59.3 bits (142), Expect = 7e-09 Identities = 51/178 (28%), Positives = 83/178 (46%), Gaps = 4/178 (2%) Frame = +2 Query: 17 GNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGE 196 G L +TVG++G G +G + +E + + D ++ ++ G F Sbjct: 111 GFSLHERTVGIVGVGNVGRR-LQARLEALGIKTLLCDPPRADCGDE-----GDF------ 158 Query: 197 QPVTWKRASSMEEVLREADVISLHPVLDK----TTYHLINPERLAMMKKEAVLVNASRGP 364 S++E+++ AD+++ H L K T HL + + + +K A+L+NA RG Sbjct: 159 --------RSLDELVQRADILTFHTPLFKDGPYKTLHLADEKLIRSLKPGAILINACRGA 210 Query: 365 VIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 538 V+D AL+ L V LDV+E EP + L K + PHIA +T EG A Sbjct: 211 VVDNTALLTCLNEGQKLSVVLDVWEGEPELNVELL-TKVDIGTPHIAG---YTLEGKA 264
>YP113_YEAST (Q02961) Putative 2-hydroxyacid dehydrogenase YPL113C (EC 1.-.-.-)| Length = 396 Score = 58.9 bits (141), Expect = 1e-08 Identities = 44/155 (28%), Positives = 75/155 (48%), Gaps = 1/155 (0%) Frame = +2 Query: 47 VIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASS 226 ++G G IG + + F M++ Y+ ++ ++K + Y ++ + P TWK A Sbjct: 222 ILGFGSIGQNIGSNLHKVFNMSIEYYK--RTGPVQKSLLDYNAKYHSDLDDPNTWKNA-- 277 Query: 227 MEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKAN 406 D+I L +T ++IN + LA K +VN RG IDE L++ L++ Sbjct: 278 --------DLIILALPSTASTNNIINRKSLAWCKDGVRIVNVGRGTCIDEDVLLDALESG 329 Query: 407 PMFRVGLDVFE-DEPYMKPGLAEMKNAVVVPHIAS 508 + GLDVF+ +E +K L + +PHI S Sbjct: 330 KVASCGLDVFKNEETRVKQELLRRWDVTALPHIGS 364
>PDXB_COXBU (Q83AR8) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 366 Score = 58.5 bits (140), Expect = 1e-08 Identities = 42/97 (43%), Positives = 55/97 (56%), Gaps = 4/97 (4%) Frame = +2 Query: 239 LREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKAN 406 L D++ LH L KT TYHLI+ L M+K +VL+NA RG VID AL L+ + Sbjct: 165 LANVDLVCLHTPLVKTGNFPTYHLIDNRFLKMLKPGSVLLNAGRGAVIDNNAL---LQCD 221 Query: 407 PMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASK 517 + LDV+E+EP + L E K + PHIA SK Sbjct: 222 HVITC-LDVWENEPTVNLQLLE-KTTIATPHIAGYSK 256
>FDH_PICAN (P33677) Formate dehydrogenase (EC 1.2.1.2) (NAD-dependent formate| dehydrogenase) (FDH) Length = 361 Score = 58.2 bits (139), Expect = 2e-08 Identities = 40/144 (27%), Positives = 70/144 (48%) Frame = +2 Query: 26 LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPV 205 ++G+ + IGAGRIG ++ L+Y+D YQS L E+ V Sbjct: 161 IEGKVIATIGAGRIGYRVLERLVAFNPKELLYYD-YQS-------------LSKEAEEKV 206 Query: 206 TWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVAL 385 +R ++E++ +AD+++++ L + L+N E L KK A LVN +RG + + Sbjct: 207 GARRVHDIKELVAQADIVTINCPLHAGSKGLVNAELLKHFKKGAWLVNTARGAICVAEDV 266 Query: 386 VEHLKANPMFRVGLDVFEDEPYMK 457 +K+ + G DV+ +P K Sbjct: 267 AAAVKSGQLRGYGGDVWFPQPAPK 290
>FDH2_YEAST (Q08987) Formate dehydrogenase 2 (EC 1.2.1.2) (NAD-dependent| formate dehydrogenase 2) Length = 376 Score = 58.2 bits (139), Expect = 2e-08 Identities = 38/144 (26%), Positives = 71/144 (49%) Frame = +2 Query: 26 LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPV 205 L+ + + +GAGRIG ++ L+Y+D YQ E NG + Sbjct: 164 LEDKIISTVGAGRIGYRVLERLVAFNPKKLLYYD-YQELPAEAINRLNEASKLFNGRGDI 222 Query: 206 TWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVAL 385 +R +E+++ ++DV++++ L K + L N + ++ MK A LVN +RG + + Sbjct: 223 V-QRVEKLEDMVAQSDVVTINCPLHKDSRGLFNKKLISHMKDGAYLVNTARGAICVAEDV 281 Query: 386 VEHLKANPMFRVGLDVFEDEPYMK 457 E +K+ + G DV++ +P K Sbjct: 282 AEAVKSGKLAGYGGDVWDKQPAPK 305
>FDH1_YEAST (Q08911) Formate dehydrogenase 1 (EC 1.2.1.2) (NAD-dependent| formate dehydrogenase 1) Length = 376 Score = 58.2 bits (139), Expect = 2e-08 Identities = 38/144 (26%), Positives = 71/144 (49%) Frame = +2 Query: 26 LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPV 205 L+ + + +GAGRIG ++ L+Y+D YQ E NG + Sbjct: 164 LEDKIISTVGAGRIGYRVLERLVAFNPKKLLYYD-YQELPAEAINRLNEASKLFNGRGDI 222 Query: 206 TWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVAL 385 +R +E+++ ++DV++++ L K + L N + ++ MK A LVN +RG + + Sbjct: 223 V-QRVEKLEDMVAQSDVVTINCPLHKDSRGLFNKKLISHMKDGAYLVNTARGAICVAEDV 281 Query: 386 VEHLKANPMFRVGLDVFEDEPYMK 457 E +K+ + G DV++ +P K Sbjct: 282 AEAVKSGKLAGYGGDVWDKQPAPK 305
>FDH_PSESR (P33160) Formate dehydrogenase (EC 1.2.1.2) (NAD-dependent formate| dehydrogenase) (FDH) Length = 400 Score = 55.5 bits (132), Expect = 1e-07 Identities = 44/144 (30%), Positives = 71/144 (49%) Frame = +2 Query: 26 LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPV 205 L+ VG + AGRIG A R + F ++L Y D + RL + V E + Sbjct: 189 LEAMHVGTVAAGRIGLAVLRRLAP-FDVHLHYTDRH---RLPESVEK---------ELNL 235 Query: 206 TWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVAL 385 TW ++ E++ DV++L+ L T H+IN E L + K+ A +VN +RG + D A+ Sbjct: 236 TWH--ATREDMYPVCDVVTLNCPLHPETEHMINDETLKLFKRGAYIVNTARGKLCDRDAV 293 Query: 386 VEHLKANPMFRVGLDVFEDEPYMK 457 L++ + DV+ +P K Sbjct: 294 ARALESGRLAGYAGDVWFPQPAPK 317
>FDH_EMENI (Q03134) Probable formate dehydrogenase (EC 1.2.1.2) (NAD-dependent| formate dehydrogenase) (FDH) Length = 377 Score = 54.7 bits (130), Expect = 2e-07 Identities = 44/161 (27%), Positives = 74/161 (45%), Gaps = 17/161 (10%) Frame = +2 Query: 26 LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPV 205 L+ + VG +G GRIG R + L+Y+D YQ R E E+ + Sbjct: 158 LENKVVGTVGVGRIGERVLRRLKPFDCKELLYYD-YQPLRPEV-------------EKEI 203 Query: 206 TWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMK-----------------KE 334 +R S+EE++ + DV++++ L + T L N E ++ MK K Sbjct: 204 GARRVDSLEEMVSQCDVVTINCPLHEKTRGLFNKELISKMKPGKSALLYLIIPMLMYHKG 263 Query: 335 AVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMK 457 + LVN +RG ++ + + E LK+ + G DV+ +P K Sbjct: 264 SWLVNTARGAIVVKEDVAEALKSGHLRGYGGDVWFPQPAPK 304
>PDXB_PORGI (Q7MV70) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 377 Score = 54.3 bits (129), Expect = 2e-07 Identities = 49/177 (27%), Positives = 80/177 (45%), Gaps = 11/177 (6%) Frame = +2 Query: 17 GNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYG-QFL---- 181 G LK + +G++G G +G L++ +AYG +FL Sbjct: 119 GFSLKEKVMGIVGVGHVGG-----------------------ELKRLASAYGMEFLLCDP 155 Query: 182 -KANGEQPVTWKRASSMEEVLREADVISLHPVL----DKTTYHLINPERL-AMMKKEAVL 343 ++ EQ ++ S + E + D+IS H L TYHLI L + K +L Sbjct: 156 PRSEAEQDNSFLPLSRLVE---QCDIISFHVPLTHEDPHATYHLIGEAFLRSCADKRPIL 212 Query: 344 VNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 514 +NA RG V D AL+ +K+ + + +D +E EP + L ++ + + PHIA S Sbjct: 213 INACRGAVADTQALIRAVKSGWLQALVIDCWEGEPDIDLSLLDLAD-IATPHIAGFS 268
>YGT5_YEAST (P53100) Putative 2-hydroxyacid dehydrogenase YGL185C (EC 1.-.-.-)| Length = 379 Score = 47.4 bits (111), Expect = 3e-05 Identities = 45/184 (24%), Positives = 72/184 (39%), Gaps = 6/184 (3%) Frame = +2 Query: 29 KGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVT 208 +G+ ++G G IG A + G M + Y + + Q + Sbjct: 196 RGKKCLILGLGSIGKQVAYKLQYGLGMEIHYCKRSEDCTMS---------------QNES 240 Query: 209 WKRASSMEEVLREADVISLHPVL-----DKTTYHLINPERLAMMKKEAVLVNASRGPVID 373 WK E + A + H ++ T HLIN + L +LVN RG ++D Sbjct: 241 WKFHLLDETIY--AKLYQFHAIVVTLPGTPQTEHLINRKFLEHCNPGLILVNLGRGKILD 298 Query: 374 EVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAV-VVPHIASASKWTREGMATLAA 550 A+ + L + +GLDVF EP + + + PH+ SA+K E LA Sbjct: 299 LRAVSDALVTGRINHLGLDVFNKEPEIDEKIRSSDRLTSITPHLGSATKDVFEQSCELAL 358 Query: 551 LNVL 562 +L Sbjct: 359 TRIL 362
>G3PD_MAIZE (Q09054) Glyceraldehyde-3-phosphate dehydrogenase, cytosolic 2 (EC| 1.2.1.12) Length = 337 Score = 33.9 bits (76), Expect = 0.33 Identities = 39/163 (23%), Positives = 66/163 (40%), Gaps = 5/163 (3%) Frame = +2 Query: 41 VGVIGAGRIGSAYARMMIEGFKMNLI-----YFDLYQSTRLEKFVTAYGQFLKANGEQPV 205 +G+ G GRIG AR+ ++ + L+ + T + K+ T +GQ Sbjct: 6 IGINGFGRIGRLVARVALQSEDVELVAVNDPFITTDYMTYMFKYDTVHGQ---------- 55 Query: 206 TWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVAL 385 WK + + L+++ + L T + + NPE + + A V S G D+ Sbjct: 56 -WKHS---DIALKDSKTL-LFGEKPVTVFGIRNPEEIPWGEAGAEYVVESTGVFTDKDKA 110 Query: 386 VEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 514 HLK V +D P G+ E K V +++AS Sbjct: 111 AAHLKGGAKKVVISAPSKDAPMFVVGVNEDKYTSDVNIVSNAS 153
>YCDW_ECOLI (P75913) Putative 2-hydroxyacid dehydrogenase ycdW (EC 1.-.-.-)| Length = 325 Score = 33.5 bits (75), Expect = 0.44 Identities = 42/162 (25%), Positives = 70/162 (43%), Gaps = 2/162 (1%) Frame = +2 Query: 38 TVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKR 217 T+G++GAG +GS A+ + F L +R K F A E+ Sbjct: 151 TIGILGAGVLGSKVAQ------SLQTWRFPLRCWSRTRKSWPGVQSF--AGREE------ 196 Query: 218 ASSMEEVLREADV-ISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEH 394 + L + V I+L P +T +IN + L + A L+N +RG + E L+ Sbjct: 197 ---LSAFLSQCRVLINLLPNTPETV-GIINQQLLEKLPDGAYLLNLARGVHVVEDDLLAA 252 Query: 395 LKANPMFRVGLDVFEDEPY-MKPGLAEMKNAVVVPHIASASK 517 L + + LDVF EP + L + + PH+A+ ++ Sbjct: 253 LDSGKVKGAMLDVFNREPLPPESPLWQHPRVTITPHVAAITR 294
>G3PC_ORYSA (Q42977) Glyceraldehyde-3-phosphate dehydrogenase, cytosolic (EC| 1.2.1.12) (PP38) Length = 336 Score = 33.1 bits (74), Expect = 0.57 Identities = 38/163 (23%), Positives = 66/163 (40%), Gaps = 5/163 (3%) Frame = +2 Query: 41 VGVIGAGRIGSAYARMMIEGFKMNLI-----YFDLYQSTRLEKFVTAYGQFLKANGEQPV 205 +G+ G GRIG AR+ ++ + L+ + T + K+ T +GQ Sbjct: 5 IGINGFGRIGRLVARVALQSEDVELVAVNDPFITTDYMTYMFKYDTVHGQ---------- 54 Query: 206 TWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVAL 385 WK S ++ + ++ PV T + + NP+ + + A V S G D+ Sbjct: 55 -WKH-SDIKIKDSKTLLLGEKPV---TVFGIRNPDEIPWAEAGAEYVVESTGVFTDKEKA 109 Query: 386 VEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 514 HLK V +D P G+ E K + +++AS Sbjct: 110 AAHLKGGAKKVVISAPSKDAPMFVCGVNEDKYTSDIDIVSNAS 152
>G3PX_HORVU (P26517) Glyceraldehyde-3-phosphate dehydrogenase, cytosolic (EC| 1.2.1.12) Length = 337 Score = 32.7 bits (73), Expect = 0.74 Identities = 38/163 (23%), Positives = 63/163 (38%), Gaps = 5/163 (3%) Frame = +2 Query: 41 VGVIGAGRIGSAYARMMIEGFKMNLI-----YFDLYQSTRLEKFVTAYGQFLKANGEQPV 205 +G+ G GRIG AR+ ++ + L+ + T + K+ T +G Sbjct: 6 IGINGFGRIGRLVARVALQSDDVELVAVNDPFITTEYMTYMFKYDTVHGH---------- 55 Query: 206 TWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVAL 385 WK + ++ + D L T + + NPE + + A V S G D+ Sbjct: 56 -WKHS----DIKLKDDKTLLFGEKPVTVFGVRNPEEIPWGEAGADYVVESTGVFTDKDKA 110 Query: 386 VEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 514 HLK V +D P G+ E K V +++AS Sbjct: 111 AAHLKGGAKKVVISAPSKDAPMFVVGVNEDKYTSDVNIVSNAS 153
>G3PC_PETHY (P26520) Glyceraldehyde-3-phosphate dehydrogenase, cytosolic (EC| 1.2.1.12) Length = 337 Score = 32.7 bits (73), Expect = 0.74 Identities = 40/166 (24%), Positives = 63/166 (37%), Gaps = 18/166 (10%) Frame = +2 Query: 41 VGVIGAGRIGSAYARMMIEGFKMNLI-----YFDLYQSTRLEKFVTAYGQFLKANGEQPV 205 +G+ G GRIG AR+ ++ + L+ + + T + K+ + +GQ Sbjct: 6 IGINGFGRIGRLVARVALQRDDVELVAVNDPFISVEYMTYMFKYDSVHGQ---------- 55 Query: 206 TWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVAL 385 WK E+ + D L T + + NPE + + A V S G D+ Sbjct: 56 -WKH----HELKAKDDKTLLFGEKPVTVFGIRNPEEIPWGEAGADYVVESTGVFTDKDKA 110 Query: 386 VEHLKAN-------------PMFRVGLDVFEDEPYMKPGLAEMKNA 484 HLK PMF VG+ +E K L + NA Sbjct: 111 AAHLKGGAKKVIISAPSKDAPMFVVGV----NEKEYKSDLTVVSNA 152
>G3PC_MAIZE (P08735) Glyceraldehyde-3-phosphate dehydrogenase, cytosolic 1 (EC| 1.2.1.12) Length = 337 Score = 32.0 bits (71), Expect = 1.3 Identities = 38/163 (23%), Positives = 67/163 (41%), Gaps = 5/163 (3%) Frame = +2 Query: 41 VGVIGAGRIGSAYARMMIEGFKMNLI-----YFDLYQSTRLEKFVTAYGQFLKANGEQPV 205 +G+ G GRIG AR+ ++ + L+ + T + K+ T +G + ++ + Sbjct: 6 IGINGFGRIGRLVARVALQSEDVELVAVNDPFITTDYMTYMFKYDTVHGHWKHSD----I 61 Query: 206 TWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVAL 385 T K + ++ + PV T + + NPE + + A V S G D+ Sbjct: 62 TLKDSKTL--------LFGDKPV---TVFGIRNPEEIPWGEAGAEYVVESTGVFTDKDKA 110 Query: 386 VEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 514 HLK V +D P G+ E K V +++AS Sbjct: 111 AAHLKGGAKKVVISAPSKDAPMFVVGVNEDKYTSDVNIVSNAS 153
>RGYR_THEMA (O51934) Reverse gyrase [Includes: Helicase (EC 3.6.1.-);| Topoisomerase (EC 5.99.1.3)] Length = 1104 Score = 31.6 bits (70), Expect = 1.7 Identities = 19/67 (28%), Positives = 34/67 (50%) Frame = +2 Query: 53 GAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSME 232 G GR S YA+++ F+ +Y D Y+ R +F +LK E+ VT + +E Sbjct: 1015 GIGR-PSTYAKIVEVLFRRGYVYEDKYKRVRPTRFGVMVYSYLKERYEKYVTEETTRRLE 1073 Query: 233 EVLREAD 253 E++ + + Sbjct: 1074 EIMDKVE 1080
>FAT_DROME (P33450) Cadherin-related tumor suppressor precursor (Protein fat)| Length = 5147 Score = 31.6 bits (70), Expect = 1.7 Identities = 18/65 (27%), Positives = 33/65 (50%) Frame = +2 Query: 125 DLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLIN 304 ++ +T L++ T+ + +T RASS+ + +DV P D TTY++ Sbjct: 2546 EISTATTLDREETSVYHLTLMAQDSSITEPRASSVNLTISVSDVNDNIPKFDSTTYNVAV 2605 Query: 305 PERLA 319 PER++ Sbjct: 2606 PERIS 2610
>SAHH_SYNY3 (P74008) Adenosylhomocysteinase (EC 3.3.1.1)| (S-adenosyl-L-homocysteine hydrolase) (AdoHcyase) Length = 425 Score = 31.2 bits (69), Expect = 2.2 Identities = 31/127 (24%), Positives = 51/127 (40%), Gaps = 1/127 (0%) Frame = +2 Query: 23 LLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQP 202 LL G+T+ V G G G A M +G ++I ++ +E + + Sbjct: 211 LLAGKTIVVAGYGWCGKGVA-MRAKGMGADVIVTEISPVPAIEAAMDGF----------- 258 Query: 203 VTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPV-IDEV 379 R M E + D+ + H+I PE A+MK A++ N+ + ID Sbjct: 259 ----RVMPMAEAAHQGDIF----ITVTGNKHVIRPEHFAVMKDGAIVCNSGHFDIEIDLK 310 Query: 380 ALVEHLK 400 +L E K Sbjct: 311 SLKEQAK 317
>APBA2_PONPY (Q5RD33) Amyloid beta A4 precursor protein-binding family A member| 2 Length = 749 Score = 30.8 bits (68), Expect = 2.8 Identities = 25/100 (25%), Positives = 41/100 (41%), Gaps = 8/100 (8%) Frame = +2 Query: 149 EKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMK 328 + F AY +FL+ANG P S +E +D+I+ + + H N E ++ Sbjct: 518 QAFSVAYQEFLRANGINP----EDLSQKEY---SDIINTQEMYNDDLIHFSNSENCKELQ 570 Query: 329 KE--------AVLVNASRGPVIDEVALVEHLKANPMFRVG 424 E V+V + G ++ V L + P R G Sbjct: 571 LEKHKGEILGVVVVESGWGSILPTVILANMMNGGPAARSG 610
>APBA2_HUMAN (Q99767) Amyloid beta A4 precursor protein-binding family A member| 2 (Neuron-specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta) Length = 749 Score = 30.8 bits (68), Expect = 2.8 Identities = 25/100 (25%), Positives = 41/100 (41%), Gaps = 8/100 (8%) Frame = +2 Query: 149 EKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMK 328 + F AY +FL+ANG P S +E +D+I+ + + H N E ++ Sbjct: 518 QAFSVAYQEFLRANGINP----EDLSQKEY---SDIINTQEMYNDDLIHFSNSENCKELQ 570 Query: 329 KE--------AVLVNASRGPVIDEVALVEHLKANPMFRVG 424 E V+V + G ++ V L + P R G Sbjct: 571 LEKHKGEILGVVVVESGWGSILPTVILANMMNGGPAARSG 610
>APBA2_RAT (O35431) Amyloid beta A4 precursor protein-binding family A member| 2 (Neuron-specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta) Length = 750 Score = 30.8 bits (68), Expect = 2.8 Identities = 25/100 (25%), Positives = 41/100 (41%), Gaps = 8/100 (8%) Frame = +2 Query: 149 EKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMK 328 + F AY +FL+ANG P S +E +D+I+ + + H N E ++ Sbjct: 519 QAFSVAYQEFLRANGINP----EDLSQKEY---SDIINTQEMYNDDLIHFSNSENCKELQ 571 Query: 329 KE--------AVLVNASRGPVIDEVALVEHLKANPMFRVG 424 E V+V + G ++ V L + P R G Sbjct: 572 LEKHKGEILGVVVVESGWGSILPTVILANMMNGGPAARSG 611
>APBA2_MOUSE (P98084) Amyloid beta A4 precursor protein-binding family A member| 2 (Neuron-specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta) Length = 750 Score = 30.8 bits (68), Expect = 2.8 Identities = 25/100 (25%), Positives = 41/100 (41%), Gaps = 8/100 (8%) Frame = +2 Query: 149 EKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMK 328 + F AY +FL+ANG P S +E +D+I+ + + H N E ++ Sbjct: 519 QAFSVAYQEFLRANGINP----EDLSQKEY---SDIINTQEMYNDDLIHFSNSENCKELQ 571 Query: 329 KE--------AVLVNASRGPVIDEVALVEHLKANPMFRVG 424 E V+V + G ++ V L + P R G Sbjct: 572 LEKHKGEILGVVVVESGWGSILPTVILANMMNGGPAARSG 611
>G3PE_MAIZE (Q43247) Glyceraldehyde-3-phosphate dehydrogenase, cytosolic 3 (EC| 1.2.1.12) Length = 337 Score = 30.4 bits (67), Expect = 3.7 Identities = 37/163 (22%), Positives = 60/163 (36%), Gaps = 5/163 (3%) Frame = +2 Query: 41 VGVIGAGRIGSAYARMMIEGFKMNLI-----YFDLYQSTRLEKFVTAYGQFLKANGEQPV 205 +G+ G GRIG AR+ ++ + L+ + T + K+ T +GQ Sbjct: 6 IGINGFGRIGRLVARVALQSDDVELVAVNDPFISTDYMTYMFKYDTVHGQ---------- 55 Query: 206 TWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVAL 385 WK EV + L + + NPE + A V S G D+ Sbjct: 56 -WKH----HEVKVKDSKTLLFGEKEVAVFGCRNPEEIPWGSVGAEYVVESTGVFTDQEKA 110 Query: 386 VEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 514 HLK V +D P G+ E + + +++AS Sbjct: 111 AAHLKGGAKKVVISAPSKDAPMFVVGVNEKEYKSDINIVSNAS 153
>PYRB_BUCAI (P57450) Aspartate carbamoyltransferase catalytic chain (EC| 2.1.3.2) (Aspartate transcarbamylase) (ATCase) Length = 310 Score = 30.0 bits (66), Expect = 4.8 Identities = 28/124 (22%), Positives = 55/124 (44%), Gaps = 11/124 (8%) Frame = +2 Query: 41 VGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRA 220 VG + GR + + + + FK N YF + ++ ++ ++ + WKR Sbjct: 161 VGDLKYGRTVHSLTQALAK-FKHNKFYFISPDALKMPNYIN------NMLDKKEIYWKRH 213 Query: 221 SSMEEVLREADVISLHPV----LDKTTYHLINPERLAMMKKEAVLVNASRG-------PV 367 +++EE++ E D++ + + LD T Y + + + A+L NA P Sbjct: 214 NNIEEIISEIDILYMTRIQKERLDSTEY---ANAKSKFVLRAAILKNARNNMKILHPLPR 270 Query: 368 IDEV 379 IDE+ Sbjct: 271 IDEI 274
>G3PC_ARATH (P25858) Glyceraldehyde-3-phosphate dehydrogenase, cytosolic (EC| 1.2.1.12) Length = 338 Score = 30.0 bits (66), Expect = 4.8 Identities = 35/151 (23%), Positives = 58/151 (38%), Gaps = 18/151 (11%) Frame = +2 Query: 41 VGVIGAGRIGSAYARMMIEGFKMNLI-----YFDLYQSTRLEKFVTAYGQFLKANGEQPV 205 +G+ G GRIG AR++++ + L+ + T + K+ + +GQ Sbjct: 8 IGINGFGRIGRLVARVVLQRDDVELVAVNDPFITTEYMTYMFKYDSVHGQ---------- 57 Query: 206 TWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVAL 385 WK E+ + + L T + + NPE + + A V S G D+ Sbjct: 58 -WKH----NELKIKDEKTLLFGEKPVTVFGIRNPEDIPWAEAGADYVVESTGVFTDKDKA 112 Query: 386 VEHLKAN-------------PMFRVGLDVFE 439 HLK PMF VG++ E Sbjct: 113 AAHLKGGAKKVVISAPSKDAPMFVVGVNEHE 143
>NODX_RHILV (P08888) Nodulation protein 10 (Nodulation protein X) (Probable| sugar acetylase) Length = 367 Score = 30.0 bits (66), Expect = 4.8 Identities = 22/85 (25%), Positives = 37/85 (43%), Gaps = 7/85 (8%) Frame = -1 Query: 369 ITGPRLAFTSTASFFIIASRSGFIRWYVVLSSTGCRLITSASLRTSSMLEALFHVTGCSP 190 +T + +S ASFF+ S F +V ++ L+ + L + +L+ LF+ T Sbjct: 67 VTDSYIRSSSAASFFVKRSLRIFPALFVNIAVMELALLVTGGLNVTGILQYLFYFTVYIL 126 Query: 189 LAFRNW-------PYAVTNFSSRVD 136 A R W PY ++ F D Sbjct: 127 TAARIWAVYFTYEPYTMSGFYGASD 151
>MDH_GLOVI (Q7NHJ3) Malate dehydrogenase (EC 1.1.1.37)| Length = 325 Score = 30.0 bits (66), Expect = 4.8 Identities = 11/32 (34%), Positives = 22/32 (68%) Frame = +2 Query: 41 VGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQ 136 V ++GAG +GSA A+ +I+G +++ D+ + Sbjct: 11 VSILGAGNVGSALAQRLIQGNVADVVLLDIVE 42
>SAHH_METKA (P58855) Adenosylhomocysteinase (EC 3.3.1.1)| (S-adenosyl-L-homocysteine hydrolase) (AdoHcyase) Length = 424 Score = 30.0 bits (66), Expect = 4.8 Identities = 35/136 (25%), Positives = 50/136 (36%), Gaps = 1/136 (0%) Frame = +2 Query: 23 LLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQP 202 LL G+TV V+G G G AR G N+I ++ +E + Sbjct: 209 LLAGKTVVVVGYGWCGRGIAR-RARGLGANVIVVEVDPIKAMEAIFDGF----------- 256 Query: 203 VTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPV-IDEV 379 R M+ E D+ + +I E + MK +L NA V ID+ Sbjct: 257 ----RVMPMDRAAEEGDIF----ITATGNRDVIRGEHIEKMKDGVILANAGHFDVEIDKE 308 Query: 380 ALVEHLKANPMFRVGL 427 L EH + R GL Sbjct: 309 YLEEHCEEKIDRRGGL 324
>G3PC_GINBI (Q39769) Glyceraldehyde-3-phosphate dehydrogenase, cytosolic (EC| 1.2.1.12) Length = 340 Score = 30.0 bits (66), Expect = 4.8 Identities = 42/166 (25%), Positives = 61/166 (36%), Gaps = 18/166 (10%) Frame = +2 Query: 41 VGVIGAGRIGSAYARMM-----IEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPV 205 +G+ G GRIG AR+ IE +N + T + K+ + +GQ Sbjct: 9 IGINGFGRIGRLVARVALLRDDIELVAVNDPFISTDYMTYMFKYDSVHGQ---------- 58 Query: 206 TWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVAL 385 WK+ EV + L T + NPE + + V S G D+ Sbjct: 59 -WKK----HEVKVKDSNTLLFGEKAVTVFGCRNPEEIPWGETGVEYVVESTGVFTDKEKA 113 Query: 386 VEHLKAN-------------PMFRVGLDVFEDEPYMKPGLAEMKNA 484 H+K PMF VG++ E KP LA + NA Sbjct: 114 AAHIKGGAKKVVITAPSKDAPMFVVGVNEHE----YKPDLAIVSNA 155
>WSC4_YEAST (P38739) Cell wall integrity and stress response component 4| precursor Length = 605 Score = 29.6 bits (65), Expect = 6.3 Identities = 28/116 (24%), Positives = 49/116 (42%) Frame = -1 Query: 492 TTTAFFISASPGFM*GSSSKTSRPTRNMGLALRCSTSATSSITGPRLAFTSTASFFIIAS 313 TTT+ +S S SS+ T+ T + STS T S+T TST S +I++ Sbjct: 181 TTTSTKLSTSIPTSTTSSTSTTTSTSS-------STSTTVSVTSSTSTTTSTTSSTLIST 233 Query: 312 RSGFIRWYVVLSSTGCRLITSASLRTSSMLEALFHVTGCSPLAFRNWPYAVTNFSS 145 + +++ + TS + TS+ + +P + N T F++ Sbjct: 234 STSSSSSSTPTTTSSAPISTSTTSSTSTSTSTTSPTSSSAPTSSSNTTPTSTTFTT 289
>MDH1_AQUAE (O67655) Malate dehydrogenase 1 (EC 1.1.1.37)| Length = 335 Score = 29.6 bits (65), Expect = 6.3 Identities = 17/49 (34%), Positives = 26/49 (53%) Frame = +2 Query: 35 QTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFL 181 +TV VIGAG +G A +++ N+ FDL + T + F G+ L Sbjct: 5 KTVAVIGAGNVGEHVASLILLKNLANVKMFDLPRKTEEKVFEPVKGKAL 53
>G3PC_SINAL (P04796) Glyceraldehyde-3-phosphate dehydrogenase, cytosolic (EC| 1.2.1.12) Length = 337 Score = 29.6 bits (65), Expect = 6.3 Identities = 35/151 (23%), Positives = 58/151 (38%), Gaps = 18/151 (11%) Frame = +2 Query: 41 VGVIGAGRIGSAYARMMIEGFKMNLI-----YFDLYQSTRLEKFVTAYGQFLKANGEQPV 205 +G+ G GRIG AR++++ + L+ + T + K+ + +GQ Sbjct: 7 IGINGFGRIGRLVARVILQRNDVELVAVNDPFITTEYMTYMFKYDSVHGQ---------- 56 Query: 206 TWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVAL 385 WK E+ + + L T + + NPE + + A V S G D+ Sbjct: 57 -WKH----NELKVKDEKTLLFGEKPVTVFGIRNPEDIPWGEAGADFVVESTGVFTDKDKA 111 Query: 386 VEHLKAN-------------PMFRVGLDVFE 439 HLK PMF VG++ E Sbjct: 112 AAHLKGGAKKVVISAPSKDAPMFVVGVNEHE 142
>NUOL_BUCAI (P57262) NADH-quinone oxidoreductase chain L (EC 1.6.99.5) (NADH| dehydrogenase I, chain L) (NDH-1, chain L) Length = 614 Score = 29.6 bits (65), Expect = 6.3 Identities = 13/50 (26%), Positives = 24/50 (48%) Frame = -1 Query: 405 LALRCSTSATSSITGPRLAFTSTASFFIIASRSGFIRWYVVLSSTGCRLI 256 ++ R S + I L T +F+++ + +G++RWYV G I Sbjct: 555 ISKRLSADPLNKIINYFLKVTQIFNFYLLKTSNGYVRWYVASMILGINFI 604
>GPDA_BACSK (Q5WGU2) Glycerol-3-phosphate dehydrogenase [NAD(P)+] (EC 1.1.1.94)| (NAD(P)H-dependent glycerol-3-phosphate dehydrogenase) Length = 340 Score = 29.6 bits (65), Expect = 6.3 Identities = 33/112 (29%), Positives = 52/112 (46%), Gaps = 3/112 (2%) Frame = +2 Query: 35 QTVGVIGAGRIGSAYARMMIE-GFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTW 211 Q + VIGAG GSA A ++ + G + L+ Q L + T + N E P T Sbjct: 2 QKIAVIGAGSWGSALAMVLADNGHDVRLVGRRQEQMDELNERHT--NESYLPNIELPTTI 59 Query: 212 KRASSMEEVLR--EADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRG 361 + + MEE L EA V+ + + T I P ++K +++AS+G Sbjct: 60 RGYTGMEEALGGVEAIVLVVPTKAMRETVRKIVP----YLQKAVPVIHASKG 107
>G3PC_TAXBA (Q41595) Glyceraldehyde-3-phosphate dehydrogenase, cytosolic (EC| 1.2.1.12) Length = 340 Score = 29.6 bits (65), Expect = 6.3 Identities = 36/151 (23%), Positives = 56/151 (37%), Gaps = 18/151 (11%) Frame = +2 Query: 41 VGVIGAGRIGSAYARMMIEGFKMNLI-----YFDLYQSTRLEKFVTAYGQFLKANGEQPV 205 +G+ G GRIG AR+ ++ + L+ + T L K+ + +GQ Sbjct: 9 IGINGFGRIGRLVARVALQRDDIELVAVNDPFISTESLTSLFKYDSVHGQ---------- 58 Query: 206 TWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVAL 385 WK+ EV + + L + NPE + + A V S G D+ Sbjct: 59 -WKK----HEVKVKDEKTLLFGEKHVAVFGCRNPEEIPWGEVGAEYVVESTGVFTDKDKA 113 Query: 386 VEHLKAN-------------PMFRVGLDVFE 439 HLK PMF VG++ E Sbjct: 114 AAHLKGGAKKVVISAPSKDAPMFVVGVNEHE 144
>LDH_BACSU (P13714) L-lactate dehydrogenase (EC 1.1.1.27) (L-LDH)| Length = 320 Score = 29.3 bits (64), Expect = 8.2 Identities = 24/77 (31%), Positives = 41/77 (53%), Gaps = 2/77 (2%) Frame = +2 Query: 41 VGVIGAGRIGSAYARMMI-EGFKMNLIYFDLYQSTRL-EKFVTAYGQFLKANGEQPVTWK 214 V +IGAG +GS+YA +I +G L+ D+ + + + +G KA G QPV K Sbjct: 8 VALIGAGFVGSSYAFALINQGITDELVVIDVNKEKAMGDVMDLPHG---KAFGLQPV--K 62 Query: 215 RASSMEEVLREADVISL 265 + E ++AD++ + Sbjct: 63 TSYGTYEDCKDADIVCI 79
>G3PC_PEA (P34922) Glyceraldehyde-3-phosphate dehydrogenase, cytosolic (EC| 1.2.1.12) Length = 338 Score = 29.3 bits (64), Expect = 8.2 Identities = 35/154 (22%), Positives = 62/154 (40%), Gaps = 18/154 (11%) Frame = +2 Query: 41 VGVIGAGRIGSAYARMMIEGFKMNLI-----YFDLYQSTRLEKFVTAYGQFLKANGEQPV 205 +G+ G GRIG AR+ ++ + L+ + T + K+ + +GQ Sbjct: 7 IGINGFGRIGRLVARVALKRDDVELVAVNDPFITTDYMTYMFKYDSVHGQ---------- 56 Query: 206 TWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVAL 385 WK + E +++++ + L T + NPE + A ++ S G D+ Sbjct: 57 -WK---NDELTVKDSNTL-LFGQKPVTVFAHRNPEEIPWASTGADIIVESTGVFTDKDKA 111 Query: 386 VEHLKAN-------------PMFRVGLDVFEDEP 448 HLK PMF VG++ E +P Sbjct: 112 AAHLKGGAKKVIISAPSKDAPMFVVGVNENEYKP 145
>FIP1_RAT (Q5U317) Pre-mRNA 3'-end-processing factor FIP1 (FIP1-like 1)| Length = 536 Score = 29.3 bits (64), Expect = 8.2 Identities = 11/19 (57%), Positives = 14/19 (73%) Frame = +2 Query: 407 PMFRVGLDVFEDEPYMKPG 463 P+ V LD FED+P+ KPG Sbjct: 150 PLLEVDLDSFEDKPWRKPG 168
>SYM_ANASP (Q8Z068) Methionyl-tRNA synthetase (EC 6.1.1.10) (Methionine--tRNA| ligase) (MetRS) Length = 530 Score = 29.3 bits (64), Expect = 8.2 Identities = 18/43 (41%), Positives = 22/43 (51%), Gaps = 4/43 (9%) Frame = -3 Query: 244 PEDLLHAGSPLPC----HGLLTVSFQELAICCDEFLEPCGLVQ 128 P LL AG PLP HG LT Q++ ++P GLVQ Sbjct: 281 PAMLLSAGLPLPDRVFGHGFLTKDGQKMGKSLGNTVDPVGLVQ 323
>NUP82_YEAST (P40368) Nucleoporin NUP82 (Nuclear pore protein NUP82)| Length = 713 Score = 29.3 bits (64), Expect = 8.2 Identities = 20/66 (30%), Positives = 31/66 (46%) Frame = -1 Query: 402 ALRCSTSATSSITGPRLAFTSTASFFIIASRSGFIRWYVVLSSTGCRLITSASLRTSSML 223 AL ++ S+ PR F+S I+ + IRWY VL+ + L S + +L Sbjct: 9 ALPIFQASLSASQSPRYIFSSQNGTRIVFIQDNIIRWYNVLTDS---LYHSLNFSRHLVL 65 Query: 222 EALFHV 205 + FHV Sbjct: 66 DDTFHV 71
>GID_STAAW (P64236) tRNA uridine 5-carboxymethylaminomethyl modification| enzyme gid Length = 435 Score = 29.3 bits (64), Expect = 8.2 Identities = 17/29 (58%), Positives = 19/29 (65%), Gaps = 1/29 (3%) Frame = +2 Query: 35 QTVGVIGAGRIGSAYARMMIE-GFKMNLI 118 QTV VIGAG GS A + E G K+NLI Sbjct: 3 QTVNVIGAGLAGSEAAYQLAERGIKVNLI 31
>GID_STAAS (Q6G9W2) tRNA uridine 5-carboxymethylaminomethyl modification| enzyme gid Length = 435 Score = 29.3 bits (64), Expect = 8.2 Identities = 17/29 (58%), Positives = 19/29 (65%), Gaps = 1/29 (3%) Frame = +2 Query: 35 QTVGVIGAGRIGSAYARMMIE-GFKMNLI 118 QTV VIGAG GS A + E G K+NLI Sbjct: 3 QTVNVIGAGLAGSEAAYQLAERGIKVNLI 31
>GID_STAAN (P64235) tRNA uridine 5-carboxymethylaminomethyl modification| enzyme gid Length = 435 Score = 29.3 bits (64), Expect = 8.2 Identities = 17/29 (58%), Positives = 19/29 (65%), Gaps = 1/29 (3%) Frame = +2 Query: 35 QTVGVIGAGRIGSAYARMMIE-GFKMNLI 118 QTV VIGAG GS A + E G K+NLI Sbjct: 3 QTVNVIGAGLAGSEAAYQLAERGIKVNLI 31
>GID_STAAM (P64234) tRNA uridine 5-carboxymethylaminomethyl modification| enzyme gid Length = 435 Score = 29.3 bits (64), Expect = 8.2 Identities = 17/29 (58%), Positives = 19/29 (65%), Gaps = 1/29 (3%) Frame = +2 Query: 35 QTVGVIGAGRIGSAYARMMIE-GFKMNLI 118 QTV VIGAG GS A + E G K+NLI Sbjct: 3 QTVNVIGAGLAGSEAAYQLAERGIKVNLI 31
>GID_STAAC (Q5HGI1) tRNA uridine 5-carboxymethylaminomethyl modification| enzyme gid Length = 435 Score = 29.3 bits (64), Expect = 8.2 Identities = 17/29 (58%), Positives = 19/29 (65%), Gaps = 1/29 (3%) Frame = +2 Query: 35 QTVGVIGAGRIGSAYARMMIE-GFKMNLI 118 QTV VIGAG GS A + E G K+NLI Sbjct: 3 QTVNVIGAGLAGSEAAYQLAERGIKVNLI 31
>YAAA_SCHPO (Q09801) Hypothetical protein C22G7.10 in chromosome I| Length = 344 Score = 29.3 bits (64), Expect = 8.2 Identities = 27/121 (22%), Positives = 48/121 (39%), Gaps = 22/121 (18%) Frame = +2 Query: 167 YGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDK-------------TTYHLINP 307 YG+ ++ + VT A S E+ E+D + +++ T P Sbjct: 17 YGETIEERNDG-VTVSNAKSPEQASEESDDSDIEFIIETKPGERAEPLGGSIATLGSTRP 75 Query: 308 ERLAMMKKEAV---------LVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKP 460 ++K AV L A P +D + V + +F + L+ F+D+P+ KP Sbjct: 76 SAKPQVEKTAVEVKTTEPQDLSTAETAPKVD-IDAVPTIDGKNIFEIDLESFDDKPWRKP 134 Query: 461 G 463 G Sbjct: 135 G 135
>ILVC_NEIMB (Q9JYI2) Ketol-acid reductoisomerase (EC 1.1.1.86)| (Acetohydroxy-acid isomeroreductase) (Alpha-keto-beta-hydroxylacil reductoisomerase) Length = 337 Score = 29.3 bits (64), Expect = 8.2 Identities = 32/111 (28%), Positives = 55/111 (49%) Frame = +2 Query: 20 NLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQ 199 +L+KG+TV +IG G G A+A + + +N++ L Q + +K A G +K Sbjct: 12 SLIKGKTVAIIGYGSQGHAHAANLKDS-GVNVV-IGLRQGSSWKK-AEAAGHVVK----- 63 Query: 200 PVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNA 352 ++ E +EADV+ L + D+T + + E A +K+ A L A Sbjct: 64 --------TVAEATKEADVVML-LLPDETMPAVYHAEVTANLKEGATLAFA 105
>ILVC_NEIMA (Q9JTI3) Ketol-acid reductoisomerase (EC 1.1.1.86)| (Acetohydroxy-acid isomeroreductase) (Alpha-keto-beta-hydroxylacil reductoisomerase) Length = 337 Score = 29.3 bits (64), Expect = 8.2 Identities = 32/111 (28%), Positives = 55/111 (49%) Frame = +2 Query: 20 NLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQ 199 +L+KG+TV +IG G G A+A + + +N++ L Q + +K A G +K Sbjct: 12 SLIKGKTVAIIGYGSQGHAHAANLKDS-GVNVV-IGLRQGSSWKK-AEAAGHVVK----- 63 Query: 200 PVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNA 352 ++ E +EADV+ L + D+T + + E A +K+ A L A Sbjct: 64 --------TVAEATKEADVVML-LLPDETMPAVYHAEVAANLKEGATLAFA 105
>FIP1_HUMAN (Q6UN15) Pre-mRNA 3'-end-processing factor FIP1 (FIP1-like 1)| (Factor interacting with PAP) (hFip1) (Rearranged in hypereosinophilia) Length = 594 Score = 29.3 bits (64), Expect = 8.2 Identities = 11/19 (57%), Positives = 14/19 (73%) Frame = +2 Query: 407 PMFRVGLDVFEDEPYMKPG 463 P+ V LD FED+P+ KPG Sbjct: 151 PLLEVDLDSFEDKPWRKPG 169
>CBID_SYNEL (Q8DKT8) Putative cobalt-precorrin-6A synthase [deacetylating] (EC| 2.1.1.-) Length = 367 Score = 29.3 bits (64), Expect = 8.2 Identities = 14/39 (35%), Positives = 20/39 (51%) Frame = -3 Query: 451 VRLILKNIEADTEHGVSLEVLHQCNLVDHRATARVHQHC 335 V LK +E H + + H + +D RATA +H HC Sbjct: 291 VEAALKFLERMVPHVLPEILSHIAHRIDQRATAYIHAHC 329
>FIP1_PONPY (Q5RAA7) Pre-mRNA 3'-end-processing factor FIP1 (FIP1-like 1)| Length = 588 Score = 29.3 bits (64), Expect = 8.2 Identities = 11/19 (57%), Positives = 14/19 (73%) Frame = +2 Query: 407 PMFRVGLDVFEDEPYMKPG 463 P+ V LD FED+P+ KPG Sbjct: 136 PLLEVDLDSFEDKPWRKPG 154
>FIP1_MOUSE (Q9D824) Pre-mRNA 3'-end-processing factor FIP1 (FIP1-like 1)| Length = 581 Score = 29.3 bits (64), Expect = 8.2 Identities = 11/19 (57%), Positives = 14/19 (73%) Frame = +2 Query: 407 PMFRVGLDVFEDEPYMKPG 463 P+ V LD FED+P+ KPG Sbjct: 150 PLLEVDLDSFEDKPWRKPG 168 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 83,765,229 Number of Sequences: 219361 Number of extensions: 1713754 Number of successful extensions: 6002 Number of sequences better than 10.0: 160 Number of HSP's better than 10.0 without gapping: 5688 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5863 length of database: 80,573,946 effective HSP length: 106 effective length of database: 57,321,680 effective search space used: 4757699440 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
